Protein kinase domain-containing protein
|
Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30018632 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 13
Homology
BLAST of Protein kinase domain-containing protein vs. Ensembl Human
Match: MAP3K3 (mitogen-activated protein kinase kinase kinase 3 [Source:HGNC Symbol;Acc:HGNC:6855]) HSP 1 Score: 160.229 bits (404), Expect = 1.787e-41 Identity = 98/265 (36.98%), Postives = 148/265 (55.85%), Query Frame = 3
Query: 612 FDKGSEIGSGAFGHVYKCKGSGIDTVFAVKWIELKKIG------VKCIEENINKFLPKLNHQRIIKYFGAIQ--TEDHLCIFMEYLSAGSLEDEIKRKRSLATENIIR-YSKQILEGLEFLHGNNIIHRDIKPDNILMSNGNNIKITDFGVSRSLLRTCGNVTKAETTIGTPNFTAPEVFLTSDEGPPYTVSADIWSLGATVINMITGRPPYCDCHPFAVPVKIVTT-KKLDLPDSQSMSKEMKEFIDKMLDPDPDQRSTAAQLL 1376
+ +G +G GAFG VY C A K ++ V +E I + L L H+RI++Y+G ++ E L IFMEY+ GS++D++K +L TE++ R Y++QILEG+ +LH N I+HRDIK NIL + N+K+ DFG S+ L C + T + GTP + +PEV S EG Y AD+WSLG TV+ M+T +PP+ + A KI T LP +S+ ++F+ ++ + QR +A +LL
Sbjct: 358 WRRGKLLGQGAFGRVYLCYDVDTGRELASKQVQFDPDSPETSKEVSALECEI-QLLKNLQHERIVQYYGCLRDRAEKTLTIFMEYMPGGSVKDQLKAYGAL-TESVTRKYTRQILEGMSYLHSNMIVHRDIKGANILRDSAGNVKLGDFGASKRLQTICMSGTGMRSVTGTPYWMSPEVI--SGEG--YGRKADVWSLGCTVVEMLTEKPPWAEYEAMAAIFKIATQPTNPQLPS--HISEHGRDFLRRIF-VEARQRPSAEELL 613
BLAST of Protein kinase domain-containing protein vs. Ensembl Human
Match: MAP3K3 (mitogen-activated protein kinase kinase kinase 3 [Source:HGNC Symbol;Acc:HGNC:6855]) HSP 1 Score: 160.229 bits (404), Expect = 1.919e-41 Identity = 98/265 (36.98%), Postives = 148/265 (55.85%), Query Frame = 3
Query: 612 FDKGSEIGSGAFGHVYKCKGSGIDTVFAVKWIELKKIG------VKCIEENINKFLPKLNHQRIIKYFGAIQ--TEDHLCIFMEYLSAGSLEDEIKRKRSLATENIIR-YSKQILEGLEFLHGNNIIHRDIKPDNILMSNGNNIKITDFGVSRSLLRTCGNVTKAETTIGTPNFTAPEVFLTSDEGPPYTVSADIWSLGATVINMITGRPPYCDCHPFAVPVKIVTT-KKLDLPDSQSMSKEMKEFIDKMLDPDPDQRSTAAQLL 1376
+ +G +G GAFG VY C A K ++ V +E I + L L H+RI++Y+G ++ E L IFMEY+ GS++D++K +L TE++ R Y++QILEG+ +LH N I+HRDIK NIL + N+K+ DFG S+ L C + T + GTP + +PEV S EG Y AD+WSLG TV+ M+T +PP+ + A KI T LP +S+ ++F+ ++ + QR +A +LL
Sbjct: 362 WRRGKLLGQGAFGRVYLCYDVDTGRELASKQVQFDPDSPETSKEVSALECEI-QLLKNLQHERIVQYYGCLRDRAEKTLTIFMEYMPGGSVKDQLKAYGAL-TESVTRKYTRQILEGMSYLHSNMIVHRDIKGANILRDSAGNVKLGDFGASKRLQTICMSGTGMRSVTGTPYWMSPEVI--SGEG--YGRKADVWSLGCTVVEMLTEKPPWAEYEAMAAIFKIATQPTNPQLPS--HISEHGRDFLRRIF-VEARQRPSAEELL 617
BLAST of Protein kinase domain-containing protein vs. Ensembl Human
Match: MAP3K3 (mitogen-activated protein kinase kinase kinase 3 [Source:HGNC Symbol;Acc:HGNC:6855]) HSP 1 Score: 160.614 bits (405), Expect = 2.270e-41 Identity = 98/265 (36.98%), Postives = 148/265 (55.85%), Query Frame = 3
Query: 612 FDKGSEIGSGAFGHVYKCKGSGIDTVFAVKWIELKKIG------VKCIEENINKFLPKLNHQRIIKYFGAIQ--TEDHLCIFMEYLSAGSLEDEIKRKRSLATENIIR-YSKQILEGLEFLHGNNIIHRDIKPDNILMSNGNNIKITDFGVSRSLLRTCGNVTKAETTIGTPNFTAPEVFLTSDEGPPYTVSADIWSLGATVINMITGRPPYCDCHPFAVPVKIVTT-KKLDLPDSQSMSKEMKEFIDKMLDPDPDQRSTAAQLL 1376
+ +G +G GAFG VY C A K ++ V +E I + L L H+RI++Y+G ++ E L IFMEY+ GS++D++K +L TE++ R Y++QILEG+ +LH N I+HRDIK NIL + N+K+ DFG S+ L C + T + GTP + +PEV S EG Y AD+WSLG TV+ M+T +PP+ + A KI T LP +S+ ++F+ ++ + QR +A +LL
Sbjct: 389 WRRGKLLGQGAFGRVYLCYDVDTGRELASKQVQFDPDSPETSKEVSALECEI-QLLKNLQHERIVQYYGCLRDRAEKTLTIFMEYMPGGSVKDQLKAYGAL-TESVTRKYTRQILEGMSYLHSNMIVHRDIKGANILRDSAGNVKLGDFGASKRLQTICMSGTGMRSVTGTPYWMSPEVI--SGEG--YGRKADVWSLGCTVVEMLTEKPPWAEYEAMAAIFKIATQPTNPQLPS--HISEHGRDFLRRIF-VEARQRPSAEELL 644
BLAST of Protein kinase domain-containing protein vs. Ensembl Human
Match: MAP3K3 (mitogen-activated protein kinase kinase kinase 3 [Source:HGNC Symbol;Acc:HGNC:6855]) HSP 1 Score: 160.229 bits (404), Expect = 2.567e-41 Identity = 98/265 (36.98%), Postives = 148/265 (55.85%), Query Frame = 3
Query: 612 FDKGSEIGSGAFGHVYKCKGSGIDTVFAVKWIELKKIG------VKCIEENINKFLPKLNHQRIIKYFGAIQ--TEDHLCIFMEYLSAGSLEDEIKRKRSLATENIIR-YSKQILEGLEFLHGNNIIHRDIKPDNILMSNGNNIKITDFGVSRSLLRTCGNVTKAETTIGTPNFTAPEVFLTSDEGPPYTVSADIWSLGATVINMITGRPPYCDCHPFAVPVKIVTT-KKLDLPDSQSMSKEMKEFIDKMLDPDPDQRSTAAQLL 1376
+ +G +G GAFG VY C A K ++ V +E I + L L H+RI++Y+G ++ E L IFMEY+ GS++D++K +L TE++ R Y++QILEG+ +LH N I+HRDIK NIL + N+K+ DFG S+ L C + T + GTP + +PEV S EG Y AD+WSLG TV+ M+T +PP+ + A KI T LP +S+ ++F+ ++ + QR +A +LL
Sbjct: 393 WRRGKLLGQGAFGRVYLCYDVDTGRELASKQVQFDPDSPETSKEVSALECEI-QLLKNLQHERIVQYYGCLRDRAEKTLTIFMEYMPGGSVKDQLKAYGAL-TESVTRKYTRQILEGMSYLHSNMIVHRDIKGANILRDSAGNVKLGDFGASKRLQTICMSGTGMRSVTGTPYWMSPEVI--SGEG--YGRKADVWSLGCTVVEMLTEKPPWAEYEAMAAIFKIATQPTNPQLPS--HISEHGRDFLRRIF-VEARQRPSAEELL 648
BLAST of Protein kinase domain-containing protein vs. Ensembl Human
Match: MAP3K3 (mitogen-activated protein kinase kinase kinase 3 [Source:HGNC Symbol;Acc:HGNC:6855]) HSP 1 Score: 160.229 bits (404), Expect = 2.567e-41 Identity = 98/265 (36.98%), Postives = 148/265 (55.85%), Query Frame = 3
Query: 612 FDKGSEIGSGAFGHVYKCKGSGIDTVFAVKWIELKKIG------VKCIEENINKFLPKLNHQRIIKYFGAIQ--TEDHLCIFMEYLSAGSLEDEIKRKRSLATENIIR-YSKQILEGLEFLHGNNIIHRDIKPDNILMSNGNNIKITDFGVSRSLLRTCGNVTKAETTIGTPNFTAPEVFLTSDEGPPYTVSADIWSLGATVINMITGRPPYCDCHPFAVPVKIVTT-KKLDLPDSQSMSKEMKEFIDKMLDPDPDQRSTAAQLL 1376
+ +G +G GAFG VY C A K ++ V +E I + L L H+RI++Y+G ++ E L IFMEY+ GS++D++K +L TE++ R Y++QILEG+ +LH N I+HRDIK NIL + N+K+ DFG S+ L C + T + GTP + +PEV S EG Y AD+WSLG TV+ M+T +PP+ + A KI T LP +S+ ++F+ ++ + QR +A +LL
Sbjct: 393 WRRGKLLGQGAFGRVYLCYDVDTGRELASKQVQFDPDSPETSKEVSALECEI-QLLKNLQHERIVQYYGCLRDRAEKTLTIFMEYMPGGSVKDQLKAYGAL-TESVTRKYTRQILEGMSYLHSNMIVHRDIKGANILRDSAGNVKLGDFGASKRLQTICMSGTGMRSVTGTPYWMSPEVI--SGEG--YGRKADVWSLGCTVVEMLTEKPPWAEYEAMAAIFKIATQPTNPQLPS--HISEHGRDFLRRIF-VEARQRPSAEELL 648
BLAST of Protein kinase domain-containing protein vs. Ensembl Celegans
Match: gck-1 (Germinal center kinase 1 [Source:UniProtKB/Swiss-Prot;Acc:H2L099]) HSP 1 Score: 157.918 bits (398), Expect = 4.607e-41 Identity = 101/262 (38.55%), Postives = 141/262 (53.82%), Query Frame = 3
Query: 612 FDKGSEIGSGAFGHVYKCKGSGIDTVFAVKWIELKKIG--VKCIEENINKFLPKLNHQRIIKYFGAIQTEDHLCIFMEYLSAGSLEDEIKRKRSLATENIIRYSKQILEGLEFLHGNNIIHRDIKPDNILMSNGNNIKITDFGVSRSLLRTCGNVTKAETTIGTPNFTAPEVFLTSDEGPPYTVSADIWSLGATVINMITGRPPYCDCHPFAVPVKIVTTKKLDLPDSQSMSKEMKEFIDKMLDPDPDQRSTAAQLLKLKLF 1391
F K IG G+FG VYK + V A+K I+L++ ++ I++ I + L + + Q + KYFG+ L I MEYL GS D K + L +I ++IL+GLE+LH IHRDIK N+L+S ++K+ DFGV+ L T V K T +G+P + APE+ S Y ADIWSLG T I + G PP+ D HP V I L SQ SK KEF++ L+ DP+ R +A+ LLK +
Sbjct: 14 FTKQERIGRGSFGEVYKGIDNRTGRVVAIKIIDLEQAEDEIEDIQQEI-QVLSQCDSQYVTKYFGSFLKGSKLWIIMEYLGGGSALDLTKSGK-LDESHIAVILREILKGLEYLHSERKIHRDIKAANVLVSEHGDVKVADFGVAGQLTET---VKKRITFVGSPFWMAPELIKQSS----YDYKADIWSLGITAIELANGEPPHSDLHPMRVLFLIPKNPPPVLQGSQ-WSKPFKEFVEMCLNKDPENRPSASTLLKHQFI 265
BLAST of Protein kinase domain-containing protein vs. Ensembl Celegans
Match: gck-1 (Germinal center kinase 1 [Source:UniProtKB/Swiss-Prot;Acc:H2L099]) HSP 1 Score: 157.918 bits (398), Expect = 5.023e-41 Identity = 101/262 (38.55%), Postives = 141/262 (53.82%), Query Frame = 3
Query: 612 FDKGSEIGSGAFGHVYKCKGSGIDTVFAVKWIELKKIG--VKCIEENINKFLPKLNHQRIIKYFGAIQTEDHLCIFMEYLSAGSLEDEIKRKRSLATENIIRYSKQILEGLEFLHGNNIIHRDIKPDNILMSNGNNIKITDFGVSRSLLRTCGNVTKAETTIGTPNFTAPEVFLTSDEGPPYTVSADIWSLGATVINMITGRPPYCDCHPFAVPVKIVTTKKLDLPDSQSMSKEMKEFIDKMLDPDPDQRSTAAQLLKLKLF 1391
F K IG G+FG VYK + V A+K I+L++ ++ I++ I + L + + Q + KYFG+ L I MEYL GS D K + L +I ++IL+GLE+LH IHRDIK N+L+S ++K+ DFGV+ L T V K T +G+P + APE+ S Y ADIWSLG T I + G PP+ D HP V I L SQ SK KEF++ L+ DP+ R +A+ LLK +
Sbjct: 19 FTKQERIGRGSFGEVYKGIDNRTGRVVAIKIIDLEQAEDEIEDIQQEI-QVLSQCDSQYVTKYFGSFLKGSKLWIIMEYLGGGSALDLTKSGK-LDESHIAVILREILKGLEYLHSERKIHRDIKAANVLVSEHGDVKVADFGVAGQLTET---VKKRITFVGSPFWMAPELIKQSS----YDYKADIWSLGITAIELANGEPPHSDLHPMRVLFLIPKNPPPVLQGSQ-WSKPFKEFVEMCLNKDPENRPSASTLLKHQFI 270
BLAST of Protein kinase domain-containing protein vs. Ensembl Celegans
Match: gck-1 (Germinal center kinase 1 [Source:UniProtKB/Swiss-Prot;Acc:H2L099]) HSP 1 Score: 157.918 bits (398), Expect = 6.162e-41 Identity = 101/262 (38.55%), Postives = 141/262 (53.82%), Query Frame = 3
Query: 612 FDKGSEIGSGAFGHVYKCKGSGIDTVFAVKWIELKKIG--VKCIEENINKFLPKLNHQRIIKYFGAIQTEDHLCIFMEYLSAGSLEDEIKRKRSLATENIIRYSKQILEGLEFLHGNNIIHRDIKPDNILMSNGNNIKITDFGVSRSLLRTCGNVTKAETTIGTPNFTAPEVFLTSDEGPPYTVSADIWSLGATVINMITGRPPYCDCHPFAVPVKIVTTKKLDLPDSQSMSKEMKEFIDKMLDPDPDQRSTAAQLLKLKLF 1391
F K IG G+FG VYK + V A+K I+L++ ++ I++ I + L + + Q + KYFG+ L I MEYL GS D K + L +I ++IL+GLE+LH IHRDIK N+L+S ++K+ DFGV+ L T V K T +G+P + APE+ S Y ADIWSLG T I + G PP+ D HP V I L SQ SK KEF++ L+ DP+ R +A+ LLK +
Sbjct: 34 FTKQERIGRGSFGEVYKGIDNRTGRVVAIKIIDLEQAEDEIEDIQQEI-QVLSQCDSQYVTKYFGSFLKGSKLWIIMEYLGGGSALDLTKSGK-LDESHIAVILREILKGLEYLHSERKIHRDIKAANVLVSEHGDVKVADFGVAGQLTET---VKKRITFVGSPFWMAPELIKQSS----YDYKADIWSLGITAIELANGEPPHSDLHPMRVLFLIPKNPPPVLQGSQ-WSKPFKEFVEMCLNKDPENRPSASTLLKHQFI 285
BLAST of Protein kinase domain-containing protein vs. Ensembl Celegans
Match: gck-1 (Germinal center kinase 1 [Source:UniProtKB/Swiss-Prot;Acc:H2L099]) HSP 1 Score: 157.147 bits (396), Expect = 2.592e-40 Identity = 101/262 (38.55%), Postives = 141/262 (53.82%), Query Frame = 3
Query: 612 FDKGSEIGSGAFGHVYKCKGSGIDTVFAVKWIELKKIG--VKCIEENINKFLPKLNHQRIIKYFGAIQTEDHLCIFMEYLSAGSLEDEIKRKRSLATENIIRYSKQILEGLEFLHGNNIIHRDIKPDNILMSNGNNIKITDFGVSRSLLRTCGNVTKAETTIGTPNFTAPEVFLTSDEGPPYTVSADIWSLGATVINMITGRPPYCDCHPFAVPVKIVTTKKLDLPDSQSMSKEMKEFIDKMLDPDPDQRSTAAQLLKLKLF 1391
F K IG G+FG VYK + V A+K I+L++ ++ I++ I + L + + Q + KYFG+ L I MEYL GS D K + L +I ++IL+GLE+LH IHRDIK N+L+S ++K+ DFGV+ L T V K T +G+P + APE+ S Y ADIWSLG T I + G PP+ D HP V I L SQ SK KEF++ L+ DP+ R +A+ LLK +
Sbjct: 184 FTKQERIGRGSFGEVYKGIDNRTGRVVAIKIIDLEQAEDEIEDIQQEI-QVLSQCDSQYVTKYFGSFLKGSKLWIIMEYLGGGSALDLTKSGK-LDESHIAVILREILKGLEYLHSERKIHRDIKAANVLVSEHGDVKVADFGVAGQLTET---VKKRITFVGSPFWMAPELIKQSS----YDYKADIWSLGITAIELANGEPPHSDLHPMRVLFLIPKNPPPVLQGSQ-WSKPFKEFVEMCLNKDPENRPSASTLLKHQFI 435
BLAST of Protein kinase domain-containing protein vs. Ensembl Celegans
Match: gck-1 (Germinal center kinase 1 [Source:UniProtKB/Swiss-Prot;Acc:H2L099]) HSP 1 Score: 155.992 bits (393), Expect = 2.611e-40 Identity = 102/263 (38.78%), Postives = 141/263 (53.61%), Query Frame = 3
Query: 612 FDKGSEIGSGAFGHVYKCKGSGIDTVFAVKWIELKKIG--VKCIEENINKFLPKLNHQRIIKYFGAIQTEDHLCIFMEYLSAGSLEDEIKRKRSLATENIIRYSKQILEGLEFLHGNNIIHRDIKPDNILMSNGNN-IKITDFGVSRSLLRTCGNVTKAETTIGTPNFTAPEVFLTSDEGPPYTVSADIWSLGATVINMITGRPPYCDCHPFAVPVKIVTTKKLDLPDSQSMSKEMKEFIDKMLDPDPDQRSTAAQLLKLKLF 1391
F K IG G+FG VYK + V A+K I+L++ ++ I++ I + L + + Q + KYFG+ L I MEYL GS D K + L +I ++IL+GLE+LH IHRDIK N+L+ +KI D+GV++ L V KA T +GTP F APEV Y++ ADIWSLG T I + G PP+ D HP V I L SQ SK KEF++ L+ DP+ R +A+ LLK +
Sbjct: 14 FTKQERIGRGSFGEVYKGIDNRTGRVVAIKIIDLEQAEDEIEDIQQEI-QVLSQCDSQYVTKYFGSFLKGSKLWIIMEYLGGGSALDLTKSGK-LDESHIAVILREILKGLEYLHSERKIHRDIKGANVLLDRQTAAVKICDYGVAKPL----DTVLKANTFVGTPFFMAPEVVKGE-----YSIEADIWSLGITAIELANGEPPHSDLHPMRVLFLIPKNPPPVLQGSQ-WSKPFKEFVEMCLNKDPENRPSASTLLKHQFI 264
BLAST of Protein kinase domain-containing protein vs. Ensembl Fly
Match: msn (gene:FBgn0010909 transcript:FBtr0333364) HSP 1 Score: 155.606 bits (392), Expect = 2.230e-39 Identity = 97/260 (37.31%), Postives = 138/260 (53.08%), Query Frame = 3
Query: 630 IGSGAFGHVYKCKGSGIDTVFAVKWIELKKIGVKCIEENINKFLPKLNHQRIIKYFGAI------QTEDHLCIFMEYLSAGSLEDEIK--RKRSLATENIIRYSKQILEGLEFLHGNNIIHRDIKPDNILMSNGNNIKITDFGVSRSLLRTCGNVTKAETTIGTPNFTAPEVFLTSDEGP--PYTVSADIWSLGATVINMITGRPPYCDCHPFAVPVKIVTTKKLDLPDSQSMSKEMKEFIDKMLDPDPDQRSTAAQLLK 1379
+G+G +G VYK + + + A+K +++ + + I+ IN NH+ I Y+GA +D L + MEY AGS+ D +K + +SL E I ++IL GL +LH N +IHRDIK N+L+++ +K+ DFGVS L RT G + T IGTP + APEV + DE P Y +D+WSLG T + M +PP CD HP I L S+ SK+ FID +L D QR LLK
Sbjct: 38 VGNGTYGQVYKGRHTKTGQLAAIKVMDVTEDEEEEIKLEINVLKKYSNHRNIATYYGAFIKKSPPGKDDQLWLVMEYCGAGSVTDLVKSTKGQSLKEEWIAYICREILRGLSYLHSNKVIHRDIKGQNVLLTDNAEVKLVDFGVSAQLDRTIG---RRNTFIGTPYWMAPEV-IACDENPDATYDNRSDLWSLGITALEMAESQPPLCDLHPMRALFLIPRNSPPRL-KSKKWSKKFHGFIDTVLVKDYHQRPYTENLLK 292
BLAST of Protein kinase domain-containing protein vs. Ensembl Fly
Match: msn (gene:FBgn0010909 transcript:FBtr0072956) HSP 1 Score: 155.606 bits (392), Expect = 2.437e-39 Identity = 97/260 (37.31%), Postives = 138/260 (53.08%), Query Frame = 3
Query: 630 IGSGAFGHVYKCKGSGIDTVFAVKWIELKKIGVKCIEENINKFLPKLNHQRIIKYFGAI------QTEDHLCIFMEYLSAGSLEDEIK--RKRSLATENIIRYSKQILEGLEFLHGNNIIHRDIKPDNILMSNGNNIKITDFGVSRSLLRTCGNVTKAETTIGTPNFTAPEVFLTSDEGP--PYTVSADIWSLGATVINMITGRPPYCDCHPFAVPVKIVTTKKLDLPDSQSMSKEMKEFIDKMLDPDPDQRSTAAQLLK 1379
+G+G +G VYK + + + A+K +++ + + I+ IN NH+ I Y+GA +D L + MEY AGS+ D +K + +SL E I ++IL GL +LH N +IHRDIK N+L+++ +K+ DFGVS L RT G + T IGTP + APEV + DE P Y +D+WSLG T + M +PP CD HP I L S+ SK+ FID +L D QR LLK
Sbjct: 38 VGNGTYGQVYKGRHTKTGQLAAIKVMDVTEDEEEEIKLEINVLKKYSNHRNIATYYGAFIKKSPPGKDDQLWLVMEYCGAGSVTDLVKSTKGQSLKEEWIAYICREILRGLSYLHSNKVIHRDIKGQNVLLTDNAEVKLVDFGVSAQLDRTIG---RRNTFIGTPYWMAPEV-IACDENPDATYDNRSDLWSLGITALEMAESQPPLCDLHPMRALFLIPRNSPPRL-KSKKWSKKFHGFIDTVLVKDYHQRPYTENLLK 292
BLAST of Protein kinase domain-containing protein vs. Ensembl Fly
Match: msn (gene:FBgn0010909 transcript:FBtr0333365) HSP 1 Score: 155.221 bits (391), Expect = 2.494e-39 Identity = 97/260 (37.31%), Postives = 138/260 (53.08%), Query Frame = 3
Query: 630 IGSGAFGHVYKCKGSGIDTVFAVKWIELKKIGVKCIEENINKFLPKLNHQRIIKYFGAI------QTEDHLCIFMEYLSAGSLEDEIK--RKRSLATENIIRYSKQILEGLEFLHGNNIIHRDIKPDNILMSNGNNIKITDFGVSRSLLRTCGNVTKAETTIGTPNFTAPEVFLTSDEGP--PYTVSADIWSLGATVINMITGRPPYCDCHPFAVPVKIVTTKKLDLPDSQSMSKEMKEFIDKMLDPDPDQRSTAAQLLK 1379
+G+G +G VYK + + + A+K +++ + + I+ IN NH+ I Y+GA +D L + MEY AGS+ D +K + +SL E I ++IL GL +LH N +IHRDIK N+L+++ +K+ DFGVS L RT G + T IGTP + APEV + DE P Y +D+WSLG T + M +PP CD HP I L S+ SK+ FID +L D QR LLK
Sbjct: 38 VGNGTYGQVYKGRHTKTGQLAAIKVMDVTEDEEEEIKLEINVLKKYSNHRNIATYYGAFIKKSPPGKDDQLWLVMEYCGAGSVTDLVKSTKGQSLKEEWIAYICREILRGLSYLHSNKVIHRDIKGQNVLLTDNAEVKLVDFGVSAQLDRTIG---RRNTFIGTPYWMAPEV-IACDENPDATYDNRSDLWSLGITALEMAESQPPLCDLHPMRALFLIPRNSPPRL-KSKKWSKKFHGFIDTVLVKDYHQRPYTENLLK 292
BLAST of Protein kinase domain-containing protein vs. Ensembl Fly
Match: msn (gene:FBgn0010909 transcript:FBtr0072957) HSP 1 Score: 155.221 bits (391), Expect = 2.494e-39 Identity = 97/260 (37.31%), Postives = 138/260 (53.08%), Query Frame = 3
Query: 630 IGSGAFGHVYKCKGSGIDTVFAVKWIELKKIGVKCIEENINKFLPKLNHQRIIKYFGAI------QTEDHLCIFMEYLSAGSLEDEIK--RKRSLATENIIRYSKQILEGLEFLHGNNIIHRDIKPDNILMSNGNNIKITDFGVSRSLLRTCGNVTKAETTIGTPNFTAPEVFLTSDEGP--PYTVSADIWSLGATVINMITGRPPYCDCHPFAVPVKIVTTKKLDLPDSQSMSKEMKEFIDKMLDPDPDQRSTAAQLLK 1379
+G+G +G VYK + + + A+K +++ + + I+ IN NH+ I Y+GA +D L + MEY AGS+ D +K + +SL E I ++IL GL +LH N +IHRDIK N+L+++ +K+ DFGVS L RT G + T IGTP + APEV + DE P Y +D+WSLG T + M +PP CD HP I L S+ SK+ FID +L D QR LLK
Sbjct: 38 VGNGTYGQVYKGRHTKTGQLAAIKVMDVTEDEEEEIKLEINVLKKYSNHRNIATYYGAFIKKSPPGKDDQLWLVMEYCGAGSVTDLVKSTKGQSLKEEWIAYICREILRGLSYLHSNKVIHRDIKGQNVLLTDNAEVKLVDFGVSAQLDRTIG---RRNTFIGTPYWMAPEV-IACDENPDATYDNRSDLWSLGITALEMAESQPPLCDLHPMRALFLIPRNSPPRL-KSKKWSKKFHGFIDTVLVKDYHQRPYTENLLK 292
BLAST of Protein kinase domain-containing protein vs. Ensembl Fly
Match: msn (gene:FBgn0010909 transcript:FBtr0333362) HSP 1 Score: 155.221 bits (391), Expect = 2.655e-39 Identity = 97/260 (37.31%), Postives = 138/260 (53.08%), Query Frame = 3
Query: 630 IGSGAFGHVYKCKGSGIDTVFAVKWIELKKIGVKCIEENINKFLPKLNHQRIIKYFGAI------QTEDHLCIFMEYLSAGSLEDEIK--RKRSLATENIIRYSKQILEGLEFLHGNNIIHRDIKPDNILMSNGNNIKITDFGVSRSLLRTCGNVTKAETTIGTPNFTAPEVFLTSDEGP--PYTVSADIWSLGATVINMITGRPPYCDCHPFAVPVKIVTTKKLDLPDSQSMSKEMKEFIDKMLDPDPDQRSTAAQLLK 1379
+G+G +G VYK + + + A+K +++ + + I+ IN NH+ I Y+GA +D L + MEY AGS+ D +K + +SL E I ++IL GL +LH N +IHRDIK N+L+++ +K+ DFGVS L RT G + T IGTP + APEV + DE P Y +D+WSLG T + M +PP CD HP I L S+ SK+ FID +L D QR LLK
Sbjct: 38 VGNGTYGQVYKGRHTKTGQLAAIKVMDVTEDEEEEIKLEINVLKKYSNHRNIATYYGAFIKKSPPGKDDQLWLVMEYCGAGSVTDLVKSTKGQSLKEEWIAYICREILRGLSYLHSNKVIHRDIKGQNVLLTDNAEVKLVDFGVSAQLDRTIG---RRNTFIGTPYWMAPEV-IACDENPDATYDNRSDLWSLGITALEMAESQPPLCDLHPMRALFLIPRNSPPRL-KSKKWSKKFHGFIDTVLVKDYHQRPYTENLLK 292
BLAST of Protein kinase domain-containing protein vs. Ensembl Zebrafish
Match: map3k3 (mitogen-activated protein kinase kinase kinase 3 [Source:ZFIN;Acc:ZDB-GENE-070910-1]) HSP 1 Score: 163.31 bits (412), Expect = 8.479e-43 Identity = 99/267 (37.08%), Postives = 149/267 (55.81%), Query Frame = 3
Query: 609 TFDKGSEIGSGAFGHVYKCKGSGIDTVFAVKWIELKKIG------VKCIEENINKFLPKLNHQRIIKYFGAIQ--TEDHLCIFMEYLSAGSLEDEIKRKRSLATENIIR-YSKQILEGLEFLHGNNIIHRDIKPDNILMSNGNNIKITDFGVSRSLLRTCGNVTKAETTIGTPNFTAPEVFLTSDEGPPYTVSADIWSLGATVINMITGRPPYCDCHPFAVPVKIVTT-KKLDLPDSQSMSKEMKEFIDKMLDPDPDQRSTAAQLLK 1379
T+ +G +G GAFG VY C A K + V +E I + L L+H+RI++Y+G ++ E L IFMEY+ GS++D++K +L TEN+ R Y++QILEG+ +LH N I+HRDIK NIL + N+K+ DFG S+ L C + T + GTP + +PEV S EG Y AD+WSLG TV+ M+T +PP+ + A KI T LP +S+ ++F+ + + + R +A +LL+
Sbjct: 343 TWRRGKLLGQGAFGRVYLCYDVDTGRELAAKQVHFDPASPETSKEVSALECEI-QLLKNLHHERIVQYYGCLRDHNEKTLTIFMEYMPGGSVKDQLKAYGAL-TENVTRKYTRQILEGMSYLHSNMIVHRDIKGANILRDSAGNVKLGDFGASKRLQTICMSSTGVRSVTGTPYWMSPEVI--SGEG--YGRKADVWSLGCTVVEMLTEKPPWAEFEAMAAIFKIATQPTNPQLPS--HISEHTRDFL-RCIFVEAKYRPSAEELLR 600
BLAST of Protein kinase domain-containing protein vs. Ensembl Zebrafish
Match: map3k3 (mitogen-activated protein kinase kinase kinase 3 [Source:ZFIN;Acc:ZDB-GENE-070910-1]) HSP 1 Score: 163.31 bits (412), Expect = 1.135e-42 Identity = 99/267 (37.08%), Postives = 149/267 (55.81%), Query Frame = 3
Query: 609 TFDKGSEIGSGAFGHVYKCKGSGIDTVFAVKWIELKKIG------VKCIEENINKFLPKLNHQRIIKYFGAIQ--TEDHLCIFMEYLSAGSLEDEIKRKRSLATENIIR-YSKQILEGLEFLHGNNIIHRDIKPDNILMSNGNNIKITDFGVSRSLLRTCGNVTKAETTIGTPNFTAPEVFLTSDEGPPYTVSADIWSLGATVINMITGRPPYCDCHPFAVPVKIVTT-KKLDLPDSQSMSKEMKEFIDKMLDPDPDQRSTAAQLLK 1379
T+ +G +G GAFG VY C A K + V +E I + L L+H+RI++Y+G ++ E L IFMEY+ GS++D++K +L TEN+ R Y++QILEG+ +LH N I+HRDIK NIL + N+K+ DFG S+ L C + T + GTP + +PEV S EG Y AD+WSLG TV+ M+T +PP+ + A KI T LP +S+ ++F+ + + + R +A +LL+
Sbjct: 355 TWRRGKLLGQGAFGRVYLCYDVDTGRELAAKQVHFDPASPETSKEVSALECEI-QLLKNLHHERIVQYYGCLRDHNEKTLTIFMEYMPGGSVKDQLKAYGAL-TENVTRKYTRQILEGMSYLHSNMIVHRDIKGANILRDSAGNVKLGDFGASKRLQTICMSSTGVRSVTGTPYWMSPEVI--SGEG--YGRKADVWSLGCTVVEMLTEKPPWAEFEAMAAIFKIATQPTNPQLPS--HISEHTRDFL-RCIFVEAKYRPSAEELLR 612
BLAST of Protein kinase domain-containing protein vs. Ensembl Zebrafish
Match: map3k3 (mitogen-activated protein kinase kinase kinase 3 [Source:ZFIN;Acc:ZDB-GENE-070910-1]) HSP 1 Score: 162.925 bits (411), Expect = 1.285e-42 Identity = 99/267 (37.08%), Postives = 149/267 (55.81%), Query Frame = 3
Query: 609 TFDKGSEIGSGAFGHVYKCKGSGIDTVFAVKWIELKKIG------VKCIEENINKFLPKLNHQRIIKYFGAIQ--TEDHLCIFMEYLSAGSLEDEIKRKRSLATENIIR-YSKQILEGLEFLHGNNIIHRDIKPDNILMSNGNNIKITDFGVSRSLLRTCGNVTKAETTIGTPNFTAPEVFLTSDEGPPYTVSADIWSLGATVINMITGRPPYCDCHPFAVPVKIVTT-KKLDLPDSQSMSKEMKEFIDKMLDPDPDQRSTAAQLLK 1379
T+ +G +G GAFG VY C A K + V +E I + L L+H+RI++Y+G ++ E L IFMEY+ GS++D++K +L TEN+ R Y++QILEG+ +LH N I+HRDIK NIL + N+K+ DFG S+ L C + T + GTP + +PEV S EG Y AD+WSLG TV+ M+T +PP+ + A KI T LP +S+ ++F+ + + + R +A +LL+
Sbjct: 361 TWRRGKLLGQGAFGRVYLCYDVDTGRELAAKQVHFDPASPETSKEVSALECEI-QLLKNLHHERIVQYYGCLRDHNEKTLTIFMEYMPGGSVKDQLKAYGAL-TENVTRKYTRQILEGMSYLHSNMIVHRDIKGANILRDSAGNVKLGDFGASKRLQTICMSSTGVRSVTGTPYWMSPEVI--SGEG--YGRKADVWSLGCTVVEMLTEKPPWAEFEAMAAIFKIATQPTNPQLPS--HISEHTRDFL-RCIFVEAKYRPSAEELLR 618
BLAST of Protein kinase domain-containing protein vs. Ensembl Zebrafish
Match: map3k2 (mitogen-activated protein kinase kinase kinase 2 [Source:ZFIN;Acc:ZDB-GENE-120215-96]) HSP 1 Score: 158.688 bits (400), Expect = 3.909e-41 Identity = 101/263 (38.40%), Postives = 147/263 (55.89%), Query Frame = 3
Query: 621 GSEIGSGAFGHVYKCKGSGIDTVFAVKWIELKKIG------VKCIEENINKFLPKLNHQRIIKYFGAIQT--EDHLCIFMEYLSAGSLEDEIKRKRSLATENIIR-YSKQILEGLEFLHGNNIIHRDIKPDNILMSNGNNIKITDFGVSRSLLRTCGNVTKAETTIGTPNFTAPEVFLTSDEGPPYTVSADIWSLGATVINMITGRPPYCDCHPFAVPVKIVTTK-KLDLPDSQSMSKEMKEFIDKMLDPDPDQRSTAAQLLK 1379
G +G GAFG V+ C + AVK ++ V +E I + L L H+RI++Y+G ++ E L IFMEY+ GS++D++K +L TEN+ R Y++QILEG+ +LH N I+HRDIK NIL + N+K+ DFG SR L C + T ++ GTP + +PEV S EG Y ADIWS+G TV+ M+T RPP+ + A KI T LP +S ++F+ ++ + QR A LL+
Sbjct: 365 GKLLGQGAFGRVFLCYDADTGRELAVKQVQFDPDSPETSKEVSALECEI-QLLKNLFHERIVQYYGCLRDTHEKTLSIFMEYMPGGSIKDQLKSYGAL-TENVTRKYTRQILEGVCYLHSNMIVHRDIKGANILRDSAGNVKLGDFGASRRLQTICLSGTGIKSVTGTPYWMSPEVI--SGEG--YGRKADIWSIGCTVVEMLTQRPPWAEFEAMAAIFKIATQPTNPTLP--PHVSDHCRDFLKRIFV-ETKQRPAAEDLLR 618
BLAST of Protein kinase domain-containing protein vs. Ensembl Zebrafish
Match: map3k2 (mitogen-activated protein kinase kinase kinase 2 [Source:ZFIN;Acc:ZDB-GENE-120215-96]) HSP 1 Score: 158.688 bits (400), Expect = 4.489e-41 Identity = 101/263 (38.40%), Postives = 147/263 (55.89%), Query Frame = 3
Query: 621 GSEIGSGAFGHVYKCKGSGIDTVFAVKWIELKKIG------VKCIEENINKFLPKLNHQRIIKYFGAIQT--EDHLCIFMEYLSAGSLEDEIKRKRSLATENIIR-YSKQILEGLEFLHGNNIIHRDIKPDNILMSNGNNIKITDFGVSRSLLRTCGNVTKAETTIGTPNFTAPEVFLTSDEGPPYTVSADIWSLGATVINMITGRPPYCDCHPFAVPVKIVTTK-KLDLPDSQSMSKEMKEFIDKMLDPDPDQRSTAAQLLK 1379
G +G GAFG V+ C + AVK ++ V +E I + L L H+RI++Y+G ++ E L IFMEY+ GS++D++K +L TEN+ R Y++QILEG+ +LH N I+HRDIK NIL + N+K+ DFG SR L C + T ++ GTP + +PEV S EG Y ADIWS+G TV+ M+T RPP+ + A KI T LP +S ++F+ ++ + QR A LL+
Sbjct: 357 GKLLGQGAFGRVFLCYDADTGRELAVKQVQFDPDSPETSKEVSALECEI-QLLKNLFHERIVQYYGCLRDTHEKTLSIFMEYMPGGSIKDQLKSYGAL-TENVTRKYTRQILEGVCYLHSNMIVHRDIKGANILRDSAGNVKLGDFGASRRLQTICLSGTGIKSVTGTPYWMSPEVI--SGEG--YGRKADIWSIGCTVVEMLTQRPPWAEFEAMAAIFKIATQPTNPTLP--PHVSDHCRDFLKRIFV-ETKQRPAAEDLLR 610
BLAST of Protein kinase domain-containing protein vs. Ensembl Xenopus
Match: samd8 (sterile alpha motif domain containing 8 [Source:Xenbase;Acc:XB-GENE-1012742]) HSP 1 Score: 165.236 bits (417), Expect = 3.305e-43 Identity = 100/266 (37.59%), Postives = 152/266 (57.14%), Query Frame = 3
Query: 612 FDKGSEIGSGAFGHVYKCKGSGIDTVFAVKWIELKKIG------VKCIEENINKFLPKLNHQRIIKYFGAIQT--EDHLCIFMEYLSAGSLEDEIKRKRSLATENIIR-YSKQILEGLEFLHGNNIIHRDIKPDNILMSNGNNIKITDFGVSRSLLRTCGNVTKAETTIGTPNFTAPEVFLTSDEGPPYTVSADIWSLGATVINMITGRPPYCDCHPFAVPVKIVTT-KKLDLPDSQSMSKEMKEFIDKMLDPDPDQRSTAAQLLK 1379
+ +G +G GAFG VY C A K ++ V +E I + L L+H RI++Y+G+++ E L IFMEY+ GS++D++K +L TEN+ R Y++QILEG+ +LH N I+HRDIK NIL + N+K+ DFG S+ L C + T + GTP + +PEV S EG Y AD+WSLG TV+ M+T +PP+ + A KI T LP + S++ ++F+ ++L + QR TA +L++
Sbjct: 365 WRRGKLLGQGAFGRVYLCYDVDTGRELAAKQVQFDPDSPETSKEVSALECEI-QLLKNLHHDRIVQYYGSLRDKGEKTLTIFMEYMPGGSVKDQLKAYGAL-TENVTRRYTRQILEGVSYLHSNMIVHRDIKGANILRDSAGNVKLGDFGASKRLQTICMSGTGIRSVTGTPYWMSPEVI--SGEG--YGRKADVWSLGCTVVEMLTEKPPWAEYEAMAAIFKIATQPTNPQLPP--NTSEQCRDFVKRIL-VEARQRPTAEELIR 621
BLAST of Protein kinase domain-containing protein vs. Ensembl Xenopus
Match: samd8 (sterile alpha motif domain containing 8 [Source:Xenbase;Acc:XB-GENE-1012742]) HSP 1 Score: 164.851 bits (416), Expect = 3.710e-43 Identity = 100/266 (37.59%), Postives = 152/266 (57.14%), Query Frame = 3
Query: 612 FDKGSEIGSGAFGHVYKCKGSGIDTVFAVKWIELKKIG------VKCIEENINKFLPKLNHQRIIKYFGAIQT--EDHLCIFMEYLSAGSLEDEIKRKRSLATENIIR-YSKQILEGLEFLHGNNIIHRDIKPDNILMSNGNNIKITDFGVSRSLLRTCGNVTKAETTIGTPNFTAPEVFLTSDEGPPYTVSADIWSLGATVINMITGRPPYCDCHPFAVPVKIVTT-KKLDLPDSQSMSKEMKEFIDKMLDPDPDQRSTAAQLLK 1379
+ +G +G GAFG VY C A K ++ V +E I + L L+H RI++Y+G+++ E L IFMEY+ GS++D++K +L TEN+ R Y++QILEG+ +LH N I+HRDIK NIL + N+K+ DFG S+ L C + T + GTP + +PEV S EG Y AD+WSLG TV+ M+T +PP+ + A KI T LP + S++ ++F+ ++L + QR TA +L++
Sbjct: 347 WRRGKLLGQGAFGRVYLCYDVDTGRELAAKQVQFDPDSPETSKEVSALECEI-QLLKNLHHDRIVQYYGSLRDKGEKTLTIFMEYMPGGSVKDQLKAYGAL-TENVTRRYTRQILEGVSYLHSNMIVHRDIKGANILRDSAGNVKLGDFGASKRLQTICMSGTGIRSVTGTPYWMSPEVI--SGEG--YGRKADVWSLGCTVVEMLTEKPPWAEYEAMAAIFKIATQPTNPQLPP--NTSEQCRDFVKRIL-VEARQRPTAEELIR 603
BLAST of Protein kinase domain-containing protein vs. Ensembl Xenopus
Match: MAP3K2 (mitogen-activated protein kinase kinase kinase 2 [Source:NCBI gene;Acc:100493570]) HSP 1 Score: 157.532 bits (397), Expect = 1.262e-40 Identity = 95/270 (35.19%), Postives = 152/270 (56.30%), Query Frame = 3
Query: 621 GSEIGSGAFGHVYKCKGSGIDTVFAVKWIELKKIGVKCIEENIN------KFLPKLNHQRIIKYFGAIQ--TEDHLCIFMEYLSAGSLEDEIKRKRSLATENIIRYSKQILEGLEFLHGNNIIHRDIKPDNILMSNGNNIKITDFGVSRSLLRTCGNVTKAETTIGTPNFTAPEVFLTSDEGPPYTVSADIWSLGATVINMITGRPPYCDCHPFAVPVKIVTTK-KLDLPDSQSMSKEMKEFIDKMLDPDPDQRSTAAQLLKLKLFSEFH 1403
G +G GAFG VY C + AVK ++ ++ +E +N + L L H+RI++Y+G ++ E L IFMEY+ GS++D++K +L +Y++QILEG+ +LH N I+HRDIK NIL + N+K+ DFG S+ L C + T ++ GTP + +PEV S EG Y ADIWS+G TV+ M+T +PP+ + A KI T LP +S+ ++F+ ++ + R ++ +LL+ F+++H
Sbjct: 342 GKLLGQGAFGRVYLCYDADTGRELAVKQVQFDPDSLETSKE-VNALECEIQLLKNLLHERIVQYYGCLRDSQEKTLSIFMEYMPGGSIKDQLKAYGALTEFVTRKYTRQILEGVHYLHSNMIVHRDIKGANILRDSSGNVKLGDFGASKRLQTICLSGTGMKSVTGTPYWMSPEVI--SGEG--YGRKADIWSVGCTVVEMLTEKPPWAEFEAMAAIFKIATQPTNPQLP--AHVSEHCRDFLKRIFV-EAKVRPSSEELLR-HTFAQYH 602
BLAST of Protein kinase domain-containing protein vs. Ensembl Xenopus
Match: MAP3K2 (mitogen-activated protein kinase kinase kinase 2 [Source:NCBI gene;Acc:100493570]) HSP 1 Score: 157.532 bits (397), Expect = 1.489e-40 Identity = 95/270 (35.19%), Postives = 152/270 (56.30%), Query Frame = 3
Query: 621 GSEIGSGAFGHVYKCKGSGIDTVFAVKWIELKKIGVKCIEENIN------KFLPKLNHQRIIKYFGAIQ--TEDHLCIFMEYLSAGSLEDEIKRKRSLATENIIRYSKQILEGLEFLHGNNIIHRDIKPDNILMSNGNNIKITDFGVSRSLLRTCGNVTKAETTIGTPNFTAPEVFLTSDEGPPYTVSADIWSLGATVINMITGRPPYCDCHPFAVPVKIVTTK-KLDLPDSQSMSKEMKEFIDKMLDPDPDQRSTAAQLLKLKLFSEFH 1403
G +G GAFG VY C + AVK ++ ++ +E +N + L L H+RI++Y+G ++ E L IFMEY+ GS++D++K +L +Y++QILEG+ +LH N I+HRDIK NIL + N+K+ DFG S+ L C + T ++ GTP + +PEV S EG Y ADIWS+G TV+ M+T +PP+ + A KI T LP +S+ ++F+ ++ + R ++ +LL+ F+++H
Sbjct: 370 GKLLGQGAFGRVYLCYDADTGRELAVKQVQFDPDSLETSKE-VNALECEIQLLKNLLHERIVQYYGCLRDSQEKTLSIFMEYMPGGSIKDQLKAYGALTEFVTRKYTRQILEGVHYLHSNMIVHRDIKGANILRDSSGNVKLGDFGASKRLQTICLSGTGMKSVTGTPYWMSPEVI--SGEG--YGRKADIWSVGCTVVEMLTEKPPWAEFEAMAAIFKIATQPTNPQLP--AHVSEHCRDFLKRIF-VEAKVRPSSEELLR-HTFAQYH 630
BLAST of Protein kinase domain-containing protein vs. Ensembl Xenopus
Match: elp4 (elongator acetyltransferase complex subunit 4 [Source:Xenbase;Acc:XB-GENE-991975]) HSP 1 Score: 154.066 bits (388), Expect = 2.383e-40 Identity = 102/284 (35.92%), Postives = 147/284 (51.76%), Query Frame = 3
Query: 546 MGLKCKSFCNH--RLCNTSLRKK---TFDKGSEIGSGAFGHVYKCKGSGIDTVFAVKWIELKKIGVKCIEENINKFLPKLNHQRIIKYFGAIQTEDHLCIFMEYLSAGSLEDEIK-RKRSLATENIIRYSKQILEGLEFLHGNNIIHRDIKPDNILMSNGNNIKITDFGVSRSLLRTCGNVTKAETTIGTPNFTAPEVFLTSDEGPPYTVSADIWSLGATVINMITGRPPYCDCHPFAVPVKIVTTKKLDLPDSQSMSKEMKEFIDKMLDPDPDQRSTAAQLLK 1379
M L+ SF + +L SL K+ FD ++G G++G V+K V A+K + ++ + I+E + + + ++KY+G+ L I MEY AGS+ D I+ R ++L E I + L+GLE+LH IHRDIK NIL++ + K+ DFGV+ L T + K T IGTP + APEV + Y ADIWSLG T I M G+PPY D HP I T + S E +F+ K L +P+QR+TA QLL+
Sbjct: 1 MCLRFFSFISKLKKLSEDSLTKQPEEVFDVLEKLGEGSYGSVFKAIHKESGQVVAIKQVPVESDLQEIIKEI--SIMQQCDSHYVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLTEEEIATILRSTLKGLEYLHFMRKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDT---MAKRNTVIGTPFWMAPEVI----QEIGYNCVADIWSLGITSIEMAEGKPPYADIHPMRAIFMIPTNPPPTFRKPELWSDEFTDFVKKCLVKNPEQRATATQLLQ 275
BLAST of Protein kinase domain-containing protein vs. Ensembl Mouse
Match: Map3k3 (mitogen-activated protein kinase kinase kinase 3 [Source:MGI Symbol;Acc:MGI:1346874]) HSP 1 Score: 159.458 bits (402), Expect = 2.875e-41 Identity = 98/265 (36.98%), Postives = 148/265 (55.85%), Query Frame = 3
Query: 612 FDKGSEIGSGAFGHVYKCKGSGIDTVFAVKWIELKKIG------VKCIEENINKFLPKLNHQRIIKYFGAIQ--TEDHLCIFMEYLSAGSLEDEIKRKRSLATENIIR-YSKQILEGLEFLHGNNIIHRDIKPDNILMSNGNNIKITDFGVSRSLLRTCGNVTKAETTIGTPNFTAPEVFLTSDEGPPYTVSADIWSLGATVINMITGRPPYCDCHPFAVPVKIVTT-KKLDLPDSQSMSKEMKEFIDKMLDPDPDQRSTAAQLL 1376
+ +G +G GAFG VY C A K ++ V +E I + L L H+RI++Y+G ++ E L IFMEY+ GS++D++K +L TE++ R Y++QILEG+ +LH N I+HRDIK NIL + N+K+ DFG S+ L C + T + GTP + +PEV S EG Y AD+WSLG TV+ M+T +PP+ + A KI T LP +S+ ++F+ ++ + QR +A +LL
Sbjct: 362 WRRGKLLGQGAFGRVYLCYDVDTGRELASKQVQFDPDSPETSKEVSALECEI-QLLKNLQHERIVQYYGCLRDRAEKILTIFMEYMPGGSVKDQLKAYGAL-TESVTRKYTRQILEGMSYLHSNMIVHRDIKGANILRDSAGNVKLGDFGASKRLQTICMSGTGIRSVTGTPYWMSPEVI--SGEG--YGRKADVWSLGCTVVEMLTEKPPWAEYEAMAAIFKIATQPTNPQLPS--HISEHGRDFLRRIF-VEARQRPSAEELL 617
BLAST of Protein kinase domain-containing protein vs. Ensembl Mouse
Match: Map3k2 (mitogen-activated protein kinase kinase kinase 2 [Source:MGI Symbol;Acc:MGI:1346873]) HSP 1 Score: 155.992 bits (393), Expect = 3.953e-40 Identity = 100/271 (36.90%), Postives = 151/271 (55.72%), Query Frame = 3
Query: 621 GSEIGSGAFGHVYKCKGSGIDTVFAVKWIELKKIGVKCIEENIN------KFLPKLNHQRIIKYFGAIQ--TEDHLCIFMEYLSAGSLEDEIKRKRSLATENIIR-YSKQILEGLEFLHGNNIIHRDIKPDNILMSNGNNIKITDFGVSRSLLRTCGNVTKAETTIGTPNFTAPEVFLTSDEGPPYTVSADIWSLGATVINMITGRPPYCDCHPFAVPVKIVTTK-KLDLPDSQSMSKEMKEFIDKMLDPDPDQRSTAAQLLKLKLFSEFH 1403
G +G GAFG VY C AVK ++ + +E +N + L L H+RI++Y+G ++ E L IFMEY+ GS++D++K +L TEN+ R Y++QILEG+ +LH N I+HRDIK NIL + NIK+ DFG S+ L C + T ++ GTP + +PEV S EG Y ADIWS+ TV+ M+T +PP+ + A KI T LP +S ++F+ ++ + R +A +LL+ +F +H
Sbjct: 359 GKLLGQGAFGRVYLCYDVDTGRELAVKQVQFNPESPETSKE-VNALECEIQLLKNLLHERIVQYYGCLRDPQEKTLSIFMEYMPGGSIKDQLKAYGAL-TENVTRKYTRQILEGVHYLHSNMIVHRDIKGANILRDSTGNIKLGDFGASKRLQTICLSGTGMKSVTGTPYWMSPEVI--SGEG--YGRKADIWSVACTVVEMLTEKPPWAEFEAMAAIFKIATQPTNPKLP--PHVSDYTRDFLKRIFV-EAKLRPSAEELLR-HMFVHYH 619
BLAST of Protein kinase domain-containing protein vs. Ensembl Mouse
Match: Stk3 (serine/threonine kinase 3 [Source:MGI Symbol;Acc:MGI:1928487]) HSP 1 Score: 149.443 bits (376), Expect = 1.451e-38 Identity = 97/271 (35.79%), Postives = 140/271 (51.66%), Query Frame = 3
Query: 579 RLCNTSLRKK---TFDKGSEIGSGAFGHVYKCKGSGIDTVFAVKWIELKKIGVKCIEENINKFLPKLNHQRIIKYFGAIQTEDHLCIFMEYLSAGSLEDEIK-RKRSLATENIIRYSKQILEGLEFLHGNNIIHRDIKPDNILMSNGNNIKITDFGVSRSLLRTCGNVTKAETTIGTPNFTAPEVFLTSDEGPPYTVSADIWSLGATVINMITGRPPYCDCHPFAVPVKIVTTKKLDLPDSQSMSKEMKEFIDKMLDPDPDQRSTAAQLLK 1379
+L SL K+ FD ++G G++G V+K V A+K + ++ + I+E + + + ++KY+G+ L I MEY AGS+ D I+ R ++L + I K L+GLE+LH IHRDIK NIL++ + K+ DFGV+ L T + K T IGTP + APEV + Y ADIWSLG T I M G+PPY D HP I T + S + +F+ K L P+QR+TA QLL+
Sbjct: 11 KLSEDSLTKQPEEVFDVLEKLGEGSYGSVFKAIHKESGQVVAIKQVPVESDLQEIIKEI--SIMQQCDSPYVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILKSTLKGLEYLHFMRKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDT---MAKRNTVIGTPFWMAPEVI----QEIGYNCVADIWSLGITSIEMAEGKPPYADIHPMRAIFMIPTNPPPTFRKPELWSDDFTDFVKKCLVKSPEQRATATQLLQ 272
BLAST of Protein kinase domain-containing protein vs. Ensembl Mouse
Match: Stk3 (serine/threonine kinase 3 [Source:MGI Symbol;Acc:MGI:1928487]) HSP 1 Score: 149.058 bits (375), Expect = 2.505e-38 Identity = 97/271 (35.79%), Postives = 140/271 (51.66%), Query Frame = 3
Query: 579 RLCNTSLRKK---TFDKGSEIGSGAFGHVYKCKGSGIDTVFAVKWIELKKIGVKCIEENINKFLPKLNHQRIIKYFGAIQTEDHLCIFMEYLSAGSLEDEIK-RKRSLATENIIRYSKQILEGLEFLHGNNIIHRDIKPDNILMSNGNNIKITDFGVSRSLLRTCGNVTKAETTIGTPNFTAPEVFLTSDEGPPYTVSADIWSLGATVINMITGRPPYCDCHPFAVPVKIVTTKKLDLPDSQSMSKEMKEFIDKMLDPDPDQRSTAAQLLK 1379
+L SL K+ FD ++G G++G V+K V A+K + ++ + I+E + + + ++KY+G+ L I MEY AGS+ D I+ R ++L + I K L+GLE+LH IHRDIK NIL++ + K+ DFGV+ L T + K T IGTP + APEV + Y ADIWSLG T I M G+PPY D HP I T + S + +F+ K L P+QR+TA QLL+
Sbjct: 13 KLSEDSLTKQPEEVFDVLEKLGEGSYGSVFKAIHKESGQVVAIKQVPVESDLQEIIKEI--SIMQQCDSPYVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILKSTLKGLEYLHFMRKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDT---MAKRNTVIGTPFWMAPEVI----QEIGYNCVADIWSLGITSIEMAEGKPPYADIHPMRAIFMIPTNPPPTFRKPELWSDDFTDFVKKCLVKSPEQRATATQLLQ 274
BLAST of Protein kinase domain-containing protein vs. Ensembl Mouse
Match: Stk10 (serine/threonine kinase 10 [Source:MGI Symbol;Acc:MGI:1099439]) HSP 1 Score: 152.525 bits (384), Expect = 2.704e-38 Identity = 95/259 (36.68%), Postives = 140/259 (54.05%), Query Frame = 3
Query: 627 EIGSGAFGHVYKCKGSGIDTVFAVKWIELKKIGVKCIEENINKFLPKL------NHQRIIKYFGAIQTEDHLCIFMEYLSAGSLED-EIKRKRSLATENIIRYSKQILEGLEFLHGNNIIHRDIKPDNILMSNGNNIKITDFGVSRSLLRTCGNVTKAETTIGTPNFTAPEVFL-TSDEGPPYTVSADIWSLGATVINMITGRPPYCDCHPFAVPVKIVTTKKLDLPDSQSMSKEMKEFIDKMLDPDPDQRSTAAQLLK 1379
E+G GAFG VYK K + A K IE K EE + ++ ++ +H I+K GA + L I +E+ G+++ ++ R L I +Q+LE L FLHG IIHRD+K N+LM+ +I++ DFGVS L+T + K ++ IGTP + APEV L + + PY ADIWSLG T+I M PP+ + +P V +KI + L S E ++F+ LD +P+ R +AAQLL+
Sbjct: 41 ELGDGAFGKVYKAKNKETGALAAAKVIETKS------EEELEDYIVEIEILATCDHPYIVKLLGAYYYDGKLWIMIEFCPGGAVDAIMLELDRGLTEPQIQVVCRQMLEALNFLHGKRIIHRDLKAGNVLMTLEGDIRLADFGVSAKNLKT---LQKRDSFIGTPYWMAPEVVLCETMKDAPYDYKADIWSLGITLIEMAQIEPPHHELNPMRVLLKIAKSDPPTLLTPSKWSVEFRDFLKIALDKNPETRPSAAQLLQ 290
BLAST of Protein kinase domain-containing protein vs. UniProt/SwissProt
Match: sp|O22042|M3K3_ARATH (Mitogen-activated protein kinase kinase kinase 3 OS=Arabidopsis thaliana OX=3702 GN=ANP3 PE=1 SV=1) HSP 1 Score: 162.925 bits (411), Expect = 1.477e-41 Identity = 96/275 (34.91%), Postives = 149/275 (54.18%), Query Frame = 3
Query: 612 FDKGSEIGSGAFGHVYKCKGSGIDTVFAVKWI---------ELKKIGVKCIEENINKFLPKLNHQRIIKYFGAIQTEDHLCIFMEYLSAGSLEDEIKRKRSLATENIIRYSKQILEGLEFLHGNNIIHRDIKPDNILMSNGNNIKITDFGVSRSLLRTCGNVTKAETTIGTPNFTAPEVFLTSDEGPPYTVSADIWSLGATVINMITGRPPYCDCHPFAVPVKIVTTKKLDLPDSQSMSKEMKEFIDKMLDPDPDQRSTAAQLLKLKLFSEFHQD 1409
+ KG IG GAFG VY + A+K + E + ++ +EE + + L L+H I++Y G ++ D L I ME++ GS+ +++ S II Y+KQ+L GLE+LH N I+HRDIK NIL+ N I++ DFG S+ ++ V A++ GTP + APEV L + ++ SADIWS+G TVI M TG+PP+ + + V + K P + +S E K+F+ K L +P R +A +LL+ + Q+
Sbjct: 68 WRKGELIGCGAFGRVYMGMNLDSGELLAIKQVLIAPSSASKEKTQGHIRELEEEV-QLLKNLSHPNIVRYLGTVRESDSLNILMEFVPGGSISSLLEKFGSFPEPVIIMYTKQLLLGLEYLHNNGIMHRDIKGANILVDNKGCIRLADFGASKKVVE-LATVNGAKSMKGTPYWMAPEVILQTG----HSFSADIWSVGCTVIEMATGKPPWSEQYQQFAAVLHIGRTKAHPPIPEDLSPEAKDFLMKCLHKEPSLRLSATELLQHPFVTGKRQE 336
BLAST of Protein kinase domain-containing protein vs. UniProt/SwissProt
Match: sp|Q54PX0|Y4251_DICDI (Probable serine/threonine-protein kinase DDB_G0284251 OS=Dictyostelium discoideum OX=44689 GN=DDB_G0284251 PE=3 SV=1) HSP 1 Score: 159.073 bits (401), Expect = 4.379e-41 Identity = 97/264 (36.74%), Postives = 141/264 (53.41%), Query Frame = 3
Query: 621 GSEIGSGAFGHVYKCKGSGIDTVFAVKWIELKKIGVKCIE--ENINKFLPKLNHQRIIKYFGAIQTEDHLCIFMEYLSAGSLEDEIKRKRSLATENIIRYSKQILEGLEFLHGNNIIHRDIKPDNILMSNGNNIKITDFGV-----SRSLLRTCGNVTKAETTIGTPNFTAPEVFLTSDEGPPYTVSADIWSLGATVINMITGRPPYCDCHPFAVPVKIVTTKKLDLPDSQSMSKEMKEFIDKMLDPDPDQRSTAAQLLKLKLF 1391
G +IG GAFG V+K A+K I+ KI ++ + + L KL H I+K G ++ + L +EY+ GSL D I++ L+ E I Y Q+L+GL +LH N +IHRDIK NIL++ IK+ DFGV S S LR + +GTP + APE S E + ++DIWSLG+T+I ++TG PPY P A +IV+ + P +SKE ++ + DP QR TA +LL+ +F
Sbjct: 39 GEKIGRGAFGQVFKGLNGKTGEFVAIKQIDSNKIDESSLQSVKGEVEILHKLRHNNIVKVLGVVEVQAQLNFILEYVENGSLRDVIEKFGPLSEELCIIYLYQMLQGLAYLHSNKVIHRDIKASNILITKEGVIKLADFGVASQIDSESQLRF--------SVVGTPYWMAPE----SIEISGCSSASDIWSLGSTMIELLTGNPPYYTLQPMAAMFRIVSDQHPPFPT--DISKEFLDYFQQSFKKDPTQRPTAQELLQHPIF 288
BLAST of Protein kinase domain-containing protein vs. UniProt/SwissProt
Match: sp|Q40541|NPK1_TOBAC (Mitogen-activated protein kinase kinase kinase NPK1 OS=Nicotiana tabacum OX=4097 GN=NPK1 PE=1 SV=1) HSP 1 Score: 161.77 bits (408), Expect = 4.666e-41 Identity = 96/275 (34.91%), Postives = 147/275 (53.45%), Query Frame = 3
Query: 612 FDKGSEIGSGAFGHVYKCKGSGIDTVFAVKWIELKKIG---------VKCIEENINKFLPKLNHQRIIKYFGAIQTEDHLCIFMEYLSAGSLEDEIKRKRSLATENIIRYSKQILEGLEFLHGNNIIHRDIKPDNILMSNGNNIKITDFGVSRSLLRTCGNVTKAETTIGTPNFTAPEVFLTSDEGPPYTVSADIWSLGATVINMITGRPPYCDCHPFAVPVKIVTTKKLDLPDSQSMSKEMKEFIDKMLDPDPDQRSTAAQLLKLKLFSEFHQD 1409
+ KG IG GAFG VY + A+K + + G V+ +EE +N L L+H I++Y G + L I +E++ GS+ + + S I Y+KQ+L GLE+LH N I+HRDIK NIL+ N IK+ DFG S+ ++ +T A++ GTP + APEV L + ++ SADIWS+G T+I M TG+PP+ + + + T K P + +S E K+F+ K L +P R +A+ LL+ + HQ+
Sbjct: 80 WRKGEMIGCGAFGRVYMGMNVDSGELLAIKEVSIAMNGASRERAQAHVRELEEEVN-LLKNLSHPNIVRYLGTAREAGSLNILLEFVPGGSISSLLGKFGSFPESVIRMYTKQLLLGLEYLHKNGIMHRDIKGANILVDNKGCIKLADFGASKKVVE-LATMTGAKSMKGTPYWMAPEVILQTG----HSFSADIWSVGCTIIEMATGKPPWSQQYQEVAALFHIGTTKSHPPIPEHLSAESKDFLLKCLQKEPHLRHSASNLLQHPFVTAEHQE 348
BLAST of Protein kinase domain-containing protein vs. UniProt/SwissProt
Match: sp|Q99759|M3K3_HUMAN (Mitogen-activated protein kinase kinase kinase 3 OS=Homo sapiens OX=9606 GN=MAP3K3 PE=1 SV=2) HSP 1 Score: 160.229 bits (404), Expect = 9.213e-41 Identity = 98/265 (36.98%), Postives = 148/265 (55.85%), Query Frame = 3
Query: 612 FDKGSEIGSGAFGHVYKCKGSGIDTVFAVKWIELKKIG------VKCIEENINKFLPKLNHQRIIKYFGAIQ--TEDHLCIFMEYLSAGSLEDEIKRKRSLATENIIR-YSKQILEGLEFLHGNNIIHRDIKPDNILMSNGNNIKITDFGVSRSLLRTCGNVTKAETTIGTPNFTAPEVFLTSDEGPPYTVSADIWSLGATVINMITGRPPYCDCHPFAVPVKIVTT-KKLDLPDSQSMSKEMKEFIDKMLDPDPDQRSTAAQLL 1376
+ +G +G GAFG VY C A K ++ V +E I + L L H+RI++Y+G ++ E L IFMEY+ GS++D++K +L TE++ R Y++QILEG+ +LH N I+HRDIK NIL + N+K+ DFG S+ L C + T + GTP + +PEV S EG Y AD+WSLG TV+ M+T +PP+ + A KI T LP +S+ ++F+ ++ + QR +A +LL
Sbjct: 362 WRRGKLLGQGAFGRVYLCYDVDTGRELASKQVQFDPDSPETSKEVSALECEI-QLLKNLQHERIVQYYGCLRDRAEKTLTIFMEYMPGGSVKDQLKAYGAL-TESVTRKYTRQILEGMSYLHSNMIVHRDIKGANILRDSAGNVKLGDFGASKRLQTICMSGTGMRSVTGTPYWMSPEVI--SGEG--YGRKADVWSLGCTVVEMLTEKPPWAEYEAMAAIFKIATQPTNPQLPS--HISEHGRDFLRRIF-VEARQRPSAEELL 617
BLAST of Protein kinase domain-containing protein vs. UniProt/SwissProt
Match: sp|Q61084|M3K3_MOUSE (Mitogen-activated protein kinase kinase kinase 3 OS=Mus musculus OX=10090 GN=Map3k3 PE=1 SV=1) HSP 1 Score: 159.458 bits (402), Expect = 2.011e-40 Identity = 98/265 (36.98%), Postives = 148/265 (55.85%), Query Frame = 3
Query: 612 FDKGSEIGSGAFGHVYKCKGSGIDTVFAVKWIELKKIG------VKCIEENINKFLPKLNHQRIIKYFGAIQ--TEDHLCIFMEYLSAGSLEDEIKRKRSLATENIIR-YSKQILEGLEFLHGNNIIHRDIKPDNILMSNGNNIKITDFGVSRSLLRTCGNVTKAETTIGTPNFTAPEVFLTSDEGPPYTVSADIWSLGATVINMITGRPPYCDCHPFAVPVKIVTT-KKLDLPDSQSMSKEMKEFIDKMLDPDPDQRSTAAQLL 1376
+ +G +G GAFG VY C A K ++ V +E I + L L H+RI++Y+G ++ E L IFMEY+ GS++D++K +L TE++ R Y++QILEG+ +LH N I+HRDIK NIL + N+K+ DFG S+ L C + T + GTP + +PEV S EG Y AD+WSLG TV+ M+T +PP+ + A KI T LP +S+ ++F+ ++ + QR +A +LL
Sbjct: 362 WRRGKLLGQGAFGRVYLCYDVDTGRELASKQVQFDPDSPETSKEVSALECEI-QLLKNLQHERIVQYYGCLRDRAEKILTIFMEYMPGGSVKDQLKAYGAL-TESVTRKYTRQILEGMSYLHSNMIVHRDIKGANILRDSAGNVKLGDFGASKRLQTICMSGTGIRSVTGTPYWMSPEVI--SGEG--YGRKADVWSLGCTVVEMLTEKPPWAEYEAMAAIFKIATQPTNPQLPS--HISEHGRDFLRRIF-VEARQRPSAEELL 617
BLAST of Protein kinase domain-containing protein vs. TrEMBL
Match: A0A0H3YJG2 (Slc42a-1 OS=Schmidtea mediterranea OX=79327 GN=slc42a-1 PE=2 SV=1) HSP 1 Score: 225.328 bits (573), Expect = 7.936e-60 Identity = 137/364 (37.64%), Postives = 205/364 (56.32%), Query Frame = 3
Query: 288 NGDLKKVSTLLNGAAIEYCDKDQRRPIHWACESGNIKVVKSLIKTKCDISARDKYNLSPLDIA-IKNQNXXXXXXXXXXXXXXXXXMMGLKCKSFCNHRLCNTSLRKKTFDKGSEIGSGAFGHVYKCKGSGIDTVFAVKWIELKKIGVKCIEENINKFLPKLNHQRIIKYFGAIQTEDHLCIFMEYLSAGSLEDEIKRKRSLATENIIRYSKQILEGLEFLHGNNIIHRDIKPDNILMSNGNNIKITDFGVSRSLLRTCGNVTKAETTIGTPNFTAPEVFLTSDEGPPYTVSADIWSLGATVINMITGRPPYCDCHPFAVPVKIVTTKKLDLPDSQSMSKEMKEFIDKMLDPDPDQRSTAAQLL 1376
N D+ K+ + +GAAI D PIH AC+ NI+ + L++ CD+ DK SPL IA + + + + + + + M LKC CNH+ C TS ++K I SG++G V+ SG D FAVK I + I + IE NIN F L H+RI+K+FGA +++ IFMEYL +L+ + +K+S +++ ++KQILE L FLH +IIHRDIKP+N+L+ N+K++DFG+S L ++ K GT + APE+ YT S DIWSLGAT+I + TG+PPY + A+ I TT++++ + M K + ID ML+ D +R +A +LL
Sbjct: 584 NNDIVKL-LIESGAAINVPDSLLMMPIHLACKVNNIEAAQLLMENNCDMVTLDKLKRSPLQIAETGDFENMIKLIKECQIIREIAAEMQLKCGKLCNHKFCYTSFQRKKIKNRKCIASGSYGTVFLYNESGTDRKFAVKKIPKQNIRARYIEANINDFKNLLCHERIVKHFGAFHKKENHYIFMEYLD--TLQKKKYQKKSPG--DLLLFAKQILEALSFLHERSIIHRDIKPENVLLDIDGNLKLSDFGLSLLLSSVAEDIQKEGRCCGTYCYAAPEIL----NAELYTCSVDIWSLGATMIQLCTGQPPYHNLGDGAIITVISTTREIEYKLPEYMPKYISNLIDHMLEKDQYKRLSAKKLL 938
BLAST of Protein kinase domain-containing protein vs. TrEMBL
Match: A0A453KR49 (Protein kinase domain-containing protein OS=Aegilops tauschii subsp. strangulata OX=200361 PE=3 SV=1) HSP 1 Score: 180.644 bits (457), Expect = 1.211e-47 Identity = 107/268 (39.93%), Postives = 157/268 (58.58%), Query Frame = 3
Query: 612 FDKGSEIGSGAFGHVYKCKGSGIDT--VFAVKWI---------ELKKIGVKCIEENINKFLPKLNHQRIIKYFGAIQTEDHLCIFMEYLSAGSLEDEIKRKRSLATENIIRYSKQILEGLEFLHGNNIIHRDIKPDNILMSNGNNIKITDFGVSRSLLRTCGNVTKAETTIGTPNFTAPEVFLTSDEGPPYTVSADIWSLGATVINMITGRPPYCDCHPFAVPVKIVTTKKLDLPDSQSMSKEMKEFIDKMLDPDPDQRSTAAQLLKL 1382
+ KG IGSGAFG VY G +DT + AVK + E + ++ +EE + K L L+H I++Y G ++ ED L I +E++ GS++ + + S I +Y++QIL+GLE+LH N IIHRDIK NIL+ N IK+ DFG S+ + + +T A+T GTP++ APEV + G +T SADIWS+G TVI M TG+PP+ + + V T K P + +S E K+F+ K L +P+ RS+A+ LLK
Sbjct: 102 WRKGEMIGSGAFGQVYL--GMNLDTGELLAVKQVLIGSTNATREKAQAHIRELEEEV-KLLKNLSHPNIVRYLGTVREEDTLNILLEFVPGGSIQSLLGKLGSFPEAVIRKYTRQILQGLEYLHSNAIIHRDIKGANILVDNKGCIKLADFGASKQVAK-LATMTAAKTMKGTPHWMAPEVIV----GSGHTFSADIWSVGCTVIEMATGKPPWSQQYQEVALLFHVGTTKSHPPIPEHISPEAKDFLLKCLQKEPELRSSASDLLKF 361
BLAST of Protein kinase domain-containing protein vs. TrEMBL
Match: K1PKP1 (Mitogen-activated protein kinase kinase kinase 2 OS=Crassostrea gigas OX=29159 GN=CGI_10008499 PE=4 SV=1) HSP 1 Score: 179.104 bits (453), Expect = 1.828e-47 Identity = 108/279 (38.71%), Postives = 152/279 (54.48%), Query Frame = 3
Query: 576 HRLCNTSLRKK-----TFDKGSEIGSGAFGHVYKCKGSGIDTVFAVKWIELKKIG------VKCIEENINKFLPKLNHQRIIKYFGAIQTEDHLCIFMEYLSAGSLEDEIKRKRSLATENIIR-YSKQILEGLEFLHGNNIIHRDIKPDNILMSNGNNIKITDFGVSRSLLRTCGNVTKAETTIGTPNFTAPEVFLTSDEGPPYTVSADIWSLGATVINMITGRPPYCDCHPFAVPVKIVTTKKLDLPDSQSMSKEMKEFIDKMLDPDPDQRSTAAQLL 1376
+ L + SL K + G+ +GSGAFG VY C A+K + L+++ V+ +E I+ L H+RI+ YFG Q + L IFMEYL GS++DEI + SL TEN+ R Y+KQ+LEGL +LH N I+HRDIK NIL NIK+ DFG S+ L+T + T + +GTP + APEV G Y ADIWS+G T++ M+T +PP+ + A KI K+ +S+ + + K D +P R TA LL
Sbjct: 47 YALADLSLSKSPRCPVNWKAGALLGSGAFGEVYVCHDKDTGRDLAMKVVRLEQMNAETSKEVRALENEIH-LLRNFEHERIVSYFGCAQDKQSLYIFMEYLPGGSVKDEITKYGSL-TENVSRKYTKQMLEGLAYLHKNVIVHRDIKGANILRDGNGNIKLGDFGASKR-LQTIVSATGLHSVVGTPYWMAPEVI----NGEGYGRKADIWSVGCTIVEMLTTKPPWAEFESMAALYKIAMEKRPHFTLPNHISELCHDVLSKAFDRNPSTRPTAIDLL 318
BLAST of Protein kinase domain-containing protein vs. TrEMBL
Match: A0A453KR43 (Protein kinase domain-containing protein OS=Aegilops tauschii subsp. strangulata OX=200361 PE=3 SV=1) HSP 1 Score: 180.259 bits (456), Expect = 1.864e-47 Identity = 107/267 (40.07%), Postives = 157/267 (58.80%), Query Frame = 3
Query: 612 FDKGSEIGSGAFGHVYKCKGSGIDT--VFAVKWI---------ELKKIGVKCIEENINKFLPKLNHQRIIKYFGAIQTEDHLCIFMEYLSAGSLEDEIKRKRSLATENIIRYSKQILEGLEFLHGNNIIHRDIKPDNILMSNGNNIKITDFGVSRSLLRTCGNVTKAETTIGTPNFTAPEVFLTSDEGPPYTVSADIWSLGATVINMITGRPPYCDCHPFAVPVKIVTTKKLDLPDSQSMSKEMKEFIDKMLDPDPDQRSTAAQLLK 1379
+ KG IGSGAFG VY G +DT + AVK + E + ++ +EE + K L L+H I++Y G ++ ED L I +E++ GS++ + + S I +Y++QIL+GLE+LH N IIHRDIK NIL+ N IK+ DFG S+ + + +T A+T GTP++ APEV + G +T SADIWS+G TVI M TG+PP+ + + V T K P + +S E K+F+ K L +P+ RS+A+ LLK
Sbjct: 87 WRKGEMIGSGAFGQVYL--GMNLDTGELLAVKQVLIGSTNATREKAQAHIRELEEEV-KLLKNLSHPNIVRYLGTVREEDTLNILLEFVPGGSIQSLLGKLGSFPEAVIRKYTRQILQGLEYLHSNAIIHRDIKGANILVDNKGCIKLADFGASKQVAK-LATMTAAKTMKGTPHWMAPEVIV----GSGHTFSADIWSVGCTVIEMATGKPPWSQQYQEVALLFHVGTTKSHPPIPEHISPEAKDFLLKCLQKEPELRSSASDLLK 345
BLAST of Protein kinase domain-containing protein vs. TrEMBL
Match: A0A210PFZ5 (Mitogen-activated protein kinase kinase kinase 2 OS=Mizuhopecten yessoensis OX=6573 GN=KP79_PYT24565 PE=4 SV=1) HSP 1 Score: 178.718 bits (452), Expect = 1.092e-46 Identity = 100/266 (37.59%), Postives = 149/266 (56.02%), Query Frame = 3
Query: 612 FDKGSEIGSGAFGHVYKCKGSGIDTVFAVKWIELKKIG------VKCIEENINKFLPKLNHQRIIKYFGAIQTEDHLCIFMEYLSAGSLEDEIKRKRSLATENIIR-YSKQILEGLEFLHGNNIIHRDIKPDNILMSNGNNIKITDFGVSRSLLRTCGNVTKAETTIGTPNFTAPEVFLTSDEGPPYTVSADIWSLGATVINMITGRPPYCDCHPFAVPVKIVTTKKLDLPDSQSMSKEMKEFIDKMLDPDPDQRSTAAQLLKLKL 1388
+ KG +GSG+FG V+ C AVK + L ++ V+ +E I + L H+RI+ YFG Q L IFMEY+ GS++DE+ + L TE + R Y++Q+LEGL FLH N I+HRDIK N+L NIK+ DFG S+ L C + T ++ +GTP++ APEV G Y AD+WSLG TV+ MI+G+PP+ + A KI T ++ + Q S+ +EF+ +P +R ++ LL+ +
Sbjct: 130 WKKGHRLGSGSFGEVFVCYDKDSGRELAVKQVNLNQMNAETSKEVRALENEI-QLLRNFQHERIVSYFGCHQDHSILSIFMEYMPGGSIKDELAKYGPL-TEGVTRKYTRQMLEGLAFLHKNVIVHRDIKAANVLRDLQGNIKLADFGASKRLHTIC-SATGFKSFVGTPHYMAPEVI----NGEGYGRKADVWSLGCTVVEMISGKPPWSELESMAAIYKIATAERPEFELPQRSSEFSREFLRLTFRRNPLERPSSEDLLRHRF 388
BLAST of Protein kinase domain-containing protein vs. Ensembl Cavefish
Match: map3k3 (mitogen-activated protein kinase kinase kinase 3 [Source:NCBI gene;Acc:103034596]) HSP 1 Score: 167.162 bits (422), Expect = 4.047e-44 Identity = 97/266 (36.47%), Postives = 149/266 (56.02%), Query Frame = 3
Query: 609 TFDKGSEIGSGAFGHVYKCKGSGIDTVFAVKWIELKKIG------VKCIEENINKFLPKLNHQRIIKYFGAIQ--TEDHLCIFMEYLSAGSLEDEIKRKRSLATENIIR-YSKQILEGLEFLHGNNIIHRDIKPDNILMSNGNNIKITDFGVSRSLLRTCGNVTKAETTIGTPNFTAPEVFLTSDEGPPYTVSADIWSLGATVINMITGRPPYCDCHPFAVPVKIVTTKKLDLPDSQSMSKEMKEFIDKMLDPDPDQRSTAAQLLK 1379
T+ +G +G GAFG VY C A K ++ V +E I + L L+H+RI++Y+G ++ E L IFMEY+ GS++D++K +L TEN+ R Y++QILEG+ +LH N I+HRDIK NIL + N+K+ DFG S+ L C + T + GTP + +PEV G Y AD+WSLG TV+ M+T +PP+ + A KI T + S + S++ ++FI ++ + R +A +LL+
Sbjct: 355 TWRRGKLLGQGAFGRVYLCYDVDTGRELAAKQVQFDPASPETSKEVSTLECEI-QLLKNLHHERIVQYYGCLRDHNEKTLTIFMEYMPGGSVKDQLKAYGAL-TENVTRKYTRQILEGMSYLHSNMIVHRDIKGANILRDSAGNVKLGDFGASKRLQTICMSSTGVRSVTGTPYWMSPEVI----SGDGYGRKADVWSLGCTVVEMLTEKPPWAEYEAMAAIFKIATQPTNPILPSHT-SEQTRDFIRRIF-VEAKHRPSAEELLR 612
BLAST of Protein kinase domain-containing protein vs. Ensembl Cavefish
Match: map3k3 (mitogen-activated protein kinase kinase kinase 3 [Source:NCBI gene;Acc:103034596]) HSP 1 Score: 167.162 bits (422), Expect = 4.047e-44 Identity = 97/266 (36.47%), Postives = 149/266 (56.02%), Query Frame = 3
Query: 609 TFDKGSEIGSGAFGHVYKCKGSGIDTVFAVKWIELKKIG------VKCIEENINKFLPKLNHQRIIKYFGAIQ--TEDHLCIFMEYLSAGSLEDEIKRKRSLATENIIR-YSKQILEGLEFLHGNNIIHRDIKPDNILMSNGNNIKITDFGVSRSLLRTCGNVTKAETTIGTPNFTAPEVFLTSDEGPPYTVSADIWSLGATVINMITGRPPYCDCHPFAVPVKIVTTKKLDLPDSQSMSKEMKEFIDKMLDPDPDQRSTAAQLLK 1379
T+ +G +G GAFG VY C A K ++ V +E I + L L+H+RI++Y+G ++ E L IFMEY+ GS++D++K +L TEN+ R Y++QILEG+ +LH N I+HRDIK NIL + N+K+ DFG S+ L C + T + GTP + +PEV G Y AD+WSLG TV+ M+T +PP+ + A KI T + S + S++ ++FI ++ + R +A +LL+
Sbjct: 355 TWRRGKLLGQGAFGRVYLCYDVDTGRELAAKQVQFDPASPETSKEVSTLECEI-QLLKNLHHERIVQYYGCLRDHNEKTLTIFMEYMPGGSVKDQLKAYGAL-TENVTRKYTRQILEGMSYLHSNMIVHRDIKGANILRDSAGNVKLGDFGASKRLQTICMSSTGVRSVTGTPYWMSPEVI----SGDGYGRKADVWSLGCTVVEMLTEKPPWAEYEAMAAIFKIATQPTNPILPSHT-SEQTRDFIRRIF-VEAKHRPSAEELLR 612
BLAST of Protein kinase domain-containing protein vs. Ensembl Cavefish
Match: map3k3 (mitogen-activated protein kinase kinase kinase 3 [Source:NCBI gene;Acc:103034596]) HSP 1 Score: 167.162 bits (422), Expect = 4.047e-44 Identity = 97/266 (36.47%), Postives = 149/266 (56.02%), Query Frame = 3
Query: 609 TFDKGSEIGSGAFGHVYKCKGSGIDTVFAVKWIELKKIG------VKCIEENINKFLPKLNHQRIIKYFGAIQ--TEDHLCIFMEYLSAGSLEDEIKRKRSLATENIIR-YSKQILEGLEFLHGNNIIHRDIKPDNILMSNGNNIKITDFGVSRSLLRTCGNVTKAETTIGTPNFTAPEVFLTSDEGPPYTVSADIWSLGATVINMITGRPPYCDCHPFAVPVKIVTTKKLDLPDSQSMSKEMKEFIDKMLDPDPDQRSTAAQLLK 1379
T+ +G +G GAFG VY C A K ++ V +E I + L L+H+RI++Y+G ++ E L IFMEY+ GS++D++K +L TEN+ R Y++QILEG+ +LH N I+HRDIK NIL + N+K+ DFG S+ L C + T + GTP + +PEV G Y AD+WSLG TV+ M+T +PP+ + A KI T + S + S++ ++FI ++ + R +A +LL+
Sbjct: 355 TWRRGKLLGQGAFGRVYLCYDVDTGRELAAKQVQFDPASPETSKEVSTLECEI-QLLKNLHHERIVQYYGCLRDHNEKTLTIFMEYMPGGSVKDQLKAYGAL-TENVTRKYTRQILEGMSYLHSNMIVHRDIKGANILRDSAGNVKLGDFGASKRLQTICMSSTGVRSVTGTPYWMSPEVI----SGDGYGRKADVWSLGCTVVEMLTEKPPWAEYEAMAAIFKIATQPTNPILPSHT-SEQTRDFIRRIF-VEAKHRPSAEELLR 612
BLAST of Protein kinase domain-containing protein vs. Ensembl Cavefish
Match: map3k2 (mitogen-activated protein kinase kinase kinase 2 [Source:NCBI gene;Acc:103026704]) HSP 1 Score: 158.688 bits (400), Expect = 3.502e-41 Identity = 101/263 (38.40%), Postives = 148/263 (56.27%), Query Frame = 3
Query: 621 GSEIGSGAFGHVYKCKGSGIDTVFAVKWIELKKIG------VKCIEENINKFLPKLNHQRIIKYFGAIQT--EDHLCIFMEYLSAGSLEDEIKRKRSLATENIIR-YSKQILEGLEFLHGNNIIHRDIKPDNILMSNGNNIKITDFGVSRSLLRTCGNVTKAETTIGTPNFTAPEVFLTSDEGPPYTVSADIWSLGATVINMITGRPPYCDCHPFAVPVKIVTTK-KLDLPDSQSMSKEMKEFIDKMLDPDPDQRSTAAQLLK 1379
G +G GAFG V+ C + AVK ++ V +E I + L L H+RI++Y+G ++ E L IFMEY+ GS++D++K +L TEN+ R Y++QILEG+ +LH N I+HRDIK NIL + N+K+ DFG SR L C + T ++ GTP + +PEV S EG Y ADIWS+G TV+ M+T RPP+ + A KI T LP +S ++F+ ++ + QR A +LL+
Sbjct: 362 GKLLGQGAFGRVFLCYDADTGRELAVKQVQFDPDSPETSKEVSALECEI-QLLKNLFHERIVQYYGCLRDTHERTLSIFMEYMPGGSIKDQLKSYGAL-TENVTRKYTRQILEGVCYLHSNMIVHRDIKGANILRDSAGNVKLGDFGASRRLQTICLSGTGIKSVTGTPYWMSPEVI--SGEG--YGRKADIWSVGCTVVEMLTLRPPWAEFEAMAAIFKIATQPTNPALP--AHVSDHCRDFLKRIFV-ETKQRPAAEELLR 615
BLAST of Protein kinase domain-containing protein vs. Ensembl Cavefish
Match: STK4 (serine/threonine kinase 4 [Source:HGNC Symbol;Acc:HGNC:11408]) HSP 1 Score: 155.992 bits (393), Expect = 3.577e-41 Identity = 96/278 (34.53%), Postives = 146/278 (52.52%), Query Frame = 3
Query: 579 RLCNTSLRKK---TFDKGSEIGSGAFGHVYKCKGSGIDTVFAVKWIELKKIGVKCIEENINKFLPKLNHQRIIKYFGAIQTEDHLCIFMEYLSAGSLEDEIK-RKRSLATENIIRYSKQILEGLEFLHGNNIIHRDIKPDNILMSNGNNIKITDFGVSRSLLRTCGNVTKAETTIGTPNFTAPEVFLTSDEGPPYTVSADIWSLGATVINMITGRPPYCDCHPFAVPVKIVTTKKLDLPDSQSMSKEMKEFIDKMLDPDPDQRSTAAQLLKLKLFSEF 1400
+L SL K+ FD ++G G++G V+K + A+K + ++ + I+E + + N +++Y+G+ L I MEY AGS+ D I+ R ++LA + I + L+GLE+LH IHRDIK NIL+++ K+ DFGV+ L T + K T IGTP + APEV + Y ADIWSLG T I M G+PPY D HP I T + S+ ++F+ + L +P+ R+TA QLL++ +F F
Sbjct: 19 KLSEDSLTKQPEEVFDVLEKLGEGSYGSVFKAHYKETGEIVAIKQVPVESDLQEIIKEI--SIMQQCNSPHVVRYYGSYFKNSDLWIVMEYCGAGSVSDIIRQRNKTLAEDEIAAILQSTLKGLEYLHFMRKIHRDIKAGNILLNSEGQAKLADFGVAGQLTDT---MAKRNTVIGTPFWMAPEVI----QEIGYNCVADIWSLGITAIEMAEGKPPYADIHPMRAIFMIPTNPPPTFRNPDQWSEPFRDFVSQCLVKNPENRATATQLLQVFIFVYF 287
BLAST of Protein kinase domain-containing protein vs. Ensembl Sea Lamprey
Match: map3k2 (mitogen-activated protein kinase kinase kinase 2 [Source:ZFIN;Acc:ZDB-GENE-120215-96]) HSP 1 Score: 165.622 bits (418), Expect = 2.624e-44 Identity = 96/256 (37.50%), Postives = 143/256 (55.86%), Query Frame = 3
Query: 612 FDKGSEIGSGAFGHVYKCKGSGIDTVFAVKWIELKKIGVKCIEENIN------KFLPKLNHQRIIKYFGAIQ--TEDHLCIFMEYLSAGSLEDEIKRKRSLATENIIR-YSKQILEGLEFLHGNNIIHRDIKPDNILMSNGNNIKITDFGVSRSLLRTCGNVTKAETTIGTPNFTAPEVFLTSDEGPPYTVSADIWSLGATVINMITGRPPYCDCHPFAVPVKIVTT---KKLDLPDSQSMSKEMKE-FIDKMLDP 1340
+ +G +G GAFG VY C + AVK ++ V+ +E +N + L L H+RI++YFG ++ + L IFMEY+ GS++D+++ +L TEN+ R Y++QILEG+ FLHGN I+HRDIK NIL + N+K+ DFG S+ L C T + GTP + +PEV G Y ADIWS+G TV+ M+T +PP+ + A KI T +L L S+ ++ F++ L P
Sbjct: 359 WQRGKLLGQGAFGRVYLCYDADTGRELAVKQVQFDPGSVETSKE-VNALECEIQLLKNLQHERIVQYFGCLRDPQQKTLSIFMEYMPGGSIKDQLRAYGAL-TENVTRKYTRQILEGVSFLHGNMIVHRDIKGANILRDSTGNVKLGDFGASKRLQTICSQGTAMRSVTGTPYWMSPEVI----NGEGYGRKADIWSVGCTVVEMLTEKPPWAEFEAMAAIFKIATQPTDPRLPLHASEHARDLLRRIFVEAKLRP 608
BLAST of Protein kinase domain-containing protein vs. Ensembl Sea Lamprey
Match: slka (STE20-like kinase a [Source:ZFIN;Acc:ZDB-GENE-050411-66]) HSP 1 Score: 145.206 bits (365), Expect = 1.169e-36 Identity = 92/264 (34.85%), Postives = 138/264 (52.27%), Query Frame = 3
Query: 627 EIGSGAFGHVYKCKGSGIDTVFAVKWIELKKIGVKCIEENINKFLPKL------NHQRIIKYFGAIQTEDHLCIFMEYLSAGSLED-EIKRKRSLATENIIRYSKQILEGLEFLHGNNIIHRDIKPDNILMSNGNNIKITDFGVSRSLLRTCGNVTKAETTIGTPNFTAPEVFL-TSDEGPPYTVSADIWSLGATVINMITGRPPYCDCHPFAVPVKIVTTKKLDLPDSQSMSKEMKEFIDKMLDPDPDQRSTAAQLLKLKLFS 1394
E+G GAFG VYK + + A K IE K EE + ++ ++ +H I+ A E+ L IF+E+ G+++ ++ +R LA I KQ+LE L +LH + IIHRD+K NIL++ ++K+ DFGVS RT + + ++ IGTP + APEV + + + PY ADIWSLG T+I + PP + +P V +KI L S E +F+ K LD +P+ R A QLL+ S
Sbjct: 38 ELGDGAFGKVYKAQNKESGVLAAAKVIETKS------EEELEDYMVEIEILALCDHPNIVGLLNAFYYENKLWIFIEFCPGGAVDAIMLELERGLAEPQIRVVCKQMLEALNYLHTHRIIHRDLKAGNILLTFEGDVKLADFGVSAKNTRT---LQRRDSFIGTPYWMAPEVVMCETMKDAPYDYKADIWSLGITLIELAQMEPPNHELNPMRVMLKIAKNDPPSLSFPSKWSAEFTDFLKKCLDKNPETRWNALQLLQHSFIS 292
BLAST of Protein kinase domain-containing protein vs. Ensembl Sea Lamprey
Match: stk25a (serine/threonine kinase 25a [Source:ZFIN;Acc:ZDB-GENE-041010-92]) HSP 1 Score: 137.117 bits (344), Expect = 2.015e-35 Identity = 98/266 (36.84%), Postives = 133/266 (50.00%), Query Frame = 3
Query: 603 KKTFDKGSEIGSGAFGHVYKCKGSGIDTVFAVKWIELKKIGVKCI--EENINKFLPKLNHQRIIKYFGAIQTEDHLCIFMEYLSAGSLEDEIKRKRSLATENIIRYSKQILEGLEFLHGNNIIHRDIK--PDNILMSNGNNIKITDFGVSRSLLRTCGNVTKAETTIGTPNFTAPEVFLTSDEGPPYTVSADIWSLGATVINMITGRPPYCDCHPFAVPVKIVTTKKLDLPDSQSMSKEMKEFIDKMLDPDPDQRSTAAQLLKLKL 1388
++ F K IG G+FG V+K + V A+K I+L++ + ++ I L + + + YFG+ L I MEYL GS D IK L I ++IL+GL++LH IHRDIK N+L+S ++K+ DFGV+ L T K T +GTP + APEV S Y ADIWSLG T I + G PP + HP V I L + SK KEF+D L+ DP R TA +LLK K
Sbjct: 23 EELFTKQERIGKGSFGEVFKGIDNRTKEVVAIKIIDLEEAEDEIEDIQQEIT-VLSQCDSPYVTHYFGSYLKGTKLWIIMEYLGGGSALDLIK-PGPLEEHQIATILREILKGLDYLHSERKIHRDIKGPAANVLLSEQGDVKLADFGVAGQLTDT---QIKRNTFVGTPFWMAPEVIKQSA----YDFKADIWSLGITAIELAKGEPPNSELHPMRVLFLIPKNNPPTL--EGNYSKAFKEFVDSCLNKDPQFRPTAKELLKHKF 277
BLAST of Protein kinase domain-containing protein vs. Ensembl Sea Lamprey
Match: MAP4K3 (mitogen-activated protein kinase kinase kinase kinase 3 [Source:HGNC Symbol;Acc:HGNC:6865]) HSP 1 Score: 132.494 bits (332), Expect = 1.421e-32 Identity = 79/260 (30.38%), Postives = 129/260 (49.62%), Query Frame = 3
Query: 603 KKTFDKGSEIGSGAFGHVYKCKGSGIDTVFAVKWIELKKIGVKCIEENINKFLPKLNHQRIIKYFGAIQTEDHLCIFMEYLSAGSLEDEIKRKRSLATENIIRYSKQILEGLEFLHGNNIIHRDIKPDNILMSNGNNIKITDFGVSRSLLRTCGNVTKAETTIGTPNFTAPEVFLTSDEGPPYTVSADIWSLGATVINMITGRPPYCDCHPFAVPVKIVTT--KKLDLPDSQSMSKEMKEFIDKMLDPDPDQRSTAAQLL 1376
++ F+ +GSG +G V+K + + A+K I+L+ + + + + H I+ Y+G+ D L I ME+ GSL+D L I +++ L+GL +LH +HRDIK NIL+++ ++K+ DFGVS + T + K ++ IGTP + APEV +G Y D+W++G T I + +PP D HP + + + L D Q S FI L +P +R TA ++L
Sbjct: 11 QEDFELAERLGSGTYGDVHKARNVQTGELVAIKIIKLEPGDDFSVIQQEIVMMKECKHTNIVAYYGSYLRHDKLWICMEHCGGGSLQDIYHVTGPLTERQIAYVTRETLQGLAYLHSEGKMHRDIKGANILLTDDGDVKLADFGVSAQITAT---IAKRKSFIGTPYWMAPEVAAVERKG-GYNHQCDVWAVGITAIELAELQPPMFDLHPMRALFLMSKSGFQPPKLRDKQKWSPVFHNFIKMALTKNPKKRPTAEKML 266
BLAST of Protein kinase domain-containing protein vs. Ensembl Sea Lamprey
Match: map3k19 (mitogen-activated protein kinase kinase kinase 19 [Source:ZFIN;Acc:ZDB-GENE-081104-140]) HSP 1 Score: 124.405 bits (311), Expect = 4.221e-32 Identity = 79/270 (29.26%), Postives = 134/270 (49.63%), Query Frame = 3
Query: 609 TFDKGSEIGSGAFGHVYKCKGSGIDTVFAVKWIELK--------KIGVKCIE----ENINKFLPKLNHQRIIKYFGAIQTEDHLCIFMEYLSAGSLEDEIKRKRSLATENIIRYSKQILEGLEFLHGNNIIHRDIKPDNILMSNGNNIKITDFGVSR--SLLRTCGNVTKAETTIGTPNFTAPEVFLTSDEGPPYTVSADIWSLGATVINMITGRPPYCDCHPFAVPVKIVTTKKLDLPDSQSMSKEMKEFIDKMLDPDPDQRSTAAQLL 1376
T+ KG+ +G GAFG V+ + + AVK +EL+ + G K E ++ + L L+H +++Y G + IFME++ G++ + ++ L Y Q+ GL +LHG+ ++H D+K N +++ +K+ DFG ++ +L +C + GT + APEV G Y AD+WSLG T+ M GRPP+ D P A + I + Q+ SKE +EF+++ D +R ++ +LL
Sbjct: 14 TWIKGNRLGKGAFGTVFLGL-TNQGKLIAVKELELRDAQSANGNQGGQKQSELQKLQDEVELLTTLHHPNVVEYLGTEMEGNRFSIFMEFVPGGTVAETVRGFGPLGESVCRSYIAQMTRGLAYLHGHGVMHGDVKGSNAVITPAGVVKLIDFGCAQRVALALSCHENGGLHSVHGTAYWMAPEVI----NGTGYARRADVWSLGCTLHEMAVGRPPFADMAPMAALLHIGIRNGIMPGLPQAFSKEAQEFVEQCFIRDKLKRPSSQELL 278
BLAST of Protein kinase domain-containing protein vs. Ensembl Yeast
Match: KIC1 (Protein kinase of the PAK/Ste20 family, required for cell integrity; physically interacts with Cdc31p (centrin), which is a component of the spindle pole body; part of the RAM network that regulates cellular polarity and morphogenesis [Source:SGD;Acc:S000001144]) HSP 1 Score: 141.739 bits (356), Expect = 8.887e-36 Identity = 95/263 (36.12%), Postives = 138/263 (52.47%), Query Frame = 3
Query: 612 FDKGSEIGSGAFGHVYKCKGSGIDTVFAVKWIELKKIG--VKCIEENINKFLPKLNH-QRIIKYFGAIQTEDHLCIFMEYLSAGSLEDEIKRKRSLATENIIRYSKQILEGLEFLHGNNIIHRDIKPDNILMSNGNNIKITDFGVSRSLLRTCGNVTKAETTIGTPNFTAPEVFLTSDEGPPYTVSADIWSLGATVINMITGRPPYCDCHPFAVPVKIVTTKKLDLPDSQSMSKEMKEFIDKMLDPDPDQRSTAAQLLKLKLF 1391
F + IG G FG VYK V+A+K + L V+ ++ I +FL L I +Y+G+ + L I ME+ + GSL + R + + I +++L L+ +H +N+IHRDIK N+L++N N+K+ DFGV+ + +T + +T GTP + APEV + EG Y DIWSLG T + TG PPYCD I+ +K L D +S S +KEFI LD DP +R +A LLK K
Sbjct: 23 FKRTEVIGRGKFGVVYKGYNVKTGRVYAIKVLNLDSDSDEVEDVQREI-QFLASLKQISNITRYYGSYLKDTSLWIIMEHCAGGSLRS-LLRPGKIDEKYIGVIMRELLVALKCIHKDNVIHRDIKAANVLITNEGNVKLCDFGVAAQVNQTS---LRRQTMAGTPYWMAPEVIM---EGVYYDTKVDIWSLGITTYEIATGNPPYCDVEALRAMQLIIKSKPPRLED-RSYSTSLKEFIALCLDEDPKERLSADDLLKSKFI 276
BLAST of Protein kinase domain-containing protein vs. Ensembl Yeast
Match: CDC15 (Protein kinase of the Mitotic Exit Network; localized to the spindle pole bodies at late anaphase; promotes mitotic exit by directly switching on the kinase activity of Dbf2p; required for spindle disassembly after meiosis II; relocalizes to the cytoplasm upon DNA replication stress [Source:SGD;Acc:S000000072]) HSP 1 Score: 137.502 bits (345), Expect = 2.178e-34 Identity = 98/257 (38.13%), Postives = 132/257 (51.36%), Query Frame = 3
Query: 630 IGSGAFGHVYKCKGSGIDTVFAVKWI------ELKKIGVKCIEENINKFLPKLNHQRIIKYFGAIQTEDHLCIFMEYLSAGSLEDEIKRKRSLATENIIR-YSKQILEGLEFLHGNNIIHRDIKPDNILMSNGNNIKITDFGVSRSLLRTCGNVTKAETTIGTPNFTAPEVFLTSDEGPPYTVSADIWSLGATVINMITGRPPYCDCHPFAVPVKIVTTKKLDLPDSQSMSKEMKEFIDKMLDPDPDQRSTAAQLLK 1379
IG G++G VYK D V A+K + EL I + L LNH I+KY G I+ L I +EY + GSL I R + +EN + Y Q L GL++LHG +IHRDIK NIL+S N +K+ DFGVS T N + A T GT N+ APE+ + G + +DIWSLGATV+ M+T PPY + + P S S S+ +K+F+ K + +R TA QLLK
Sbjct: 31 IGRGSYGVVYKAINKHTDQVVAIKEVVYENDEELNDIMAEI------SLLKNLNHNNIVKYHGFIRKSYELYILLEYCANGSLRRLISRSSTGLSENESKTYVTQTLLGLKYLHGEGVIHRDIKAANILLSADNTVKLADFGVS-----TIVN-SSALTLAGTLNWMAPEIL--GNRGA--STLSDIWSLGATVVEMLTKNPPYHNLTD--ANIYYAVENDTYYPPS-SFSEPLKDFLSKCFVKNMYKRPTADQLLK 268
BLAST of Protein kinase domain-containing protein vs. Ensembl Yeast
Match: STE20 (Cdc42p-activated signal transducing kinase; involved in pheromone response, pseudohyphal/invasive growth, vacuole inheritance, down-regulation of sterol uptake; GBB motif binds Ste4p; member of the PAK (p21-activated kinase) family [Source:SGD;Acc:S000000999]) HSP 1 Score: 136.732 bits (343), Expect = 3.460e-34 Identity = 90/265 (33.96%), Postives = 133/265 (50.19%), Query Frame = 3
Query: 627 EIGSGAFGHVYKCKGSGIDTVFAVKWIELKKIGVKCIEENINKFLPKLNHQRIIKYFGAIQTEDHLCIFMEYLSAGSLEDEIKRKRSLATENII-RYSKQILEGLEFLHGNNIIHRDIKPDNILMSNGNNIKITDFGVSRSLLRTCGNVT----KAETTIGTPNFTAPEVFLTSDEGPPYTVSADIWSLGATVINMITGRPPYCDCHPFAVPVKIVTTKKLDLPDSQSMSKEMKEFIDKMLDPDPDQRSTAAQLLKLKLFSEFHQ 1406
+IG GA G VY G + A+K + L+K K + N + H I+ + + + L + MEY+ GSL D + + TE I ++ L GLEFLH ++HRDIK DNIL+S +IK+TDFG C + K T +GTP + APEV + GP DIWSLG +I MI G PPY + P I T L + +++S +K+F+D L +P+ R++A +LL + +E +
Sbjct: 625 KIGQGASGGVYTAYEIGTNVSVAIKQMNLEKQPKKELIINEILVMKGSKHPNIVNFIDSYVLKGDLWVIMEYMEGGSLTDVVTH--CILTEGQIGAVCRETLSGLEFLHSKGVLHRDIKSDNILLSMEGDIKLTDFGF-------CAQINELNLKRTTMVGTPYWMAPEVVSRKEYGP----KVDIWSLGIMIIEMIEGEPPYLNETPLRALYLIATNGTPKLKEPENLSSSLKKFLDWCLCVEPEDRASATELLHDEYITEIAE 876
BLAST of Protein kinase domain-containing protein vs. Ensembl Yeast
Match: SSK22 (MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway; functionally redundant with Ssk2p; interacts with and is activated by Ssk1p; phosphorylates Pbs2p; SSK22 has a paralog, SSK2, that arose from the whole genome duplication [Source:SGD;Acc:S000000669]) HSP 1 Score: 136.346 bits (342), Expect = 6.113e-34 Identity = 95/284 (33.45%), Postives = 147/284 (51.76%), Query Frame = 3
Query: 588 NTSLRKKTFDKGSEIGSGAFGHVYKCKGSGIDTVFAVKWIE------LKKIGVKCIEENINKFLPKLNHQRIIKYFGAIQTEDHLCIFMEYLSAGSLEDEIKRKRSLATENIIR-YSKQILEGLEFLHGNNIIHRDIKPDNILMSNGNNIKITDFGVSRSLL----RTCGNV--------TKA-ETTIGTPNFTAPEVFLTSDEGPPYTVSADIWSLGATVINMITGRPPYCDC-HPFAVPVKIVTTKKLDLPDSQSMSKEMKEFIDKMLDPDPDQRSTAAQLL 1376
N S+R + K S IG G FG VY + AVK I+ +KKI I+E + L LNH I++Y+G D + IFMEY GSL + R + E + + Y+ ++LEGL +LH + ++HRDIKP+NIL+ IK DFG +R+++ RT N TK+ +GTP + APE ++ + D+W+LG V+ M TGR P+ + + +A+ + + LP+ M+ + F+++ L DP R+TA +LL
Sbjct: 1029 NVSMR---WQKRSFIGGGTFGQVYSAINLENGEILAVKEIKIHDTTTMKKI-FPLIKEEMT-VLEMLNHPNIVQYYGVEVHRDKVNIFMEYCEGGSLASLLDHGR-IEDEMVTQVYTFELLEGLAYLHQSGVVHRDIKPENILLDFNGIIKYVDFGTARTVVGSRTRTVRNAAVQDFGVETKSLNEMMGTPMYMAPET-ISGSAVKGKLGADDVWALGCVVLEMATGRRPWSNLDNEWAIMYHVAAGRIPQLPNRDEMTAAGRAFLERCLVQDPTMRATAVELL 1305
BLAST of Protein kinase domain-containing protein vs. Ensembl Yeast
Match: STE11 (Signal transducing MEK kinase; involved in pheromone response and pseudohyphal/invasive growth pathways where it phosphorylates Ste7p, and the high osmolarity response pathway, via phosphorylation of Pbs2p; regulated by Ste20p and Ste50p; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000004354]) HSP 1 Score: 127.872 bits (320), Expect = 1.804e-31 Identity = 94/302 (31.13%), Postives = 138/302 (45.70%), Query Frame = 3
Query: 606 KTFDKGSEIGSGAFGHVYKCKGSGIDTVFAVKWIELKK--IGVKC-------------------------------IEENINK-----------FLPKLNHQRIIKYFGAIQTEDHLCIFMEYLSAGSLEDEIKRKRSLATENIIRYSKQILEGLEFLHGNNIIHRDIKPDNILMSNGNNIKITDFGVSRSLLRTCGNVTKAETTIGTPNFTAPEVFLTSDEGPPYTVSADIWSLGATVINMITGRPPYCDCHPFAVPVKIVTTKKLDLPDSQSMSKEMKEFIDKMLDPDPDQRSTAAQLLK 1379
K + KG+ IGSG+FG VY + + AVK +E+K IGV +NI++ L +L+H+ I+ Y+GA Q +L IF+EY+ GS+ + I +++QIL G+ +LH NIIHRDIK NIL+ +KITDFG+S+ L K + G+ + +PEV + T ADIWS G VI M TG+ P+ D KI T ++P + E K F+ K + D R +A +LL+
Sbjct: 413 KNWLKGACIGSGSFGSVYLGMNAHTGELMAVKQVEIKNNNIGVPTDNNKQANSDENNEQEEQQEKIEDVGAVSHPKTNQNIHRKMVDALQHEMNLLKELHHENIVTYYGASQEGGNLNIFLEYVPGGSVSSMLNNYGPFEESLITNFTRQILIGVAYLHKKNIIHRDIKGANILIDIKGCVKITDFGISKKLSPLNKKQNKRASLQGSVFWMSPEVV----KQTATTAKADIWSTGCVVIEMFTGKHPFPDFSQMQAIFKIGTNTTPEIP--SWATSEGKNFLRKAFELDYQYRPSALELLQ 708
BLAST of Protein kinase domain-containing protein vs. Ensembl Nematostella
Match: EDO41410 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S4G7]) HSP 1 Score: 171.4 bits (433), Expect = 4.333e-49 Identity = 103/269 (38.29%), Postives = 151/269 (56.13%), Query Frame = 3
Query: 612 FDKGSEIGSGAFGHVYKCKGSGIDTVFAVKWIELKKIG------VKCIEENINKFLPKLNHQRIIKYFGAIQTED-HLCIFMEYLSAGSLEDEIKRKRSLATENIIRYSKQILEGLEFLHGNNIIHRDIKPDNILMSNGNNIKITDFGVSRSLLRTCGNVTKAETTIGTPNFTAPEVFLTSDEGPPYTVSADIWSLGATVINMITGRPPYCDCHPFAVPVKIVTT-KKLDLPDSQSMSKEMKEFIDKMLDPDPDQRSTAAQLLKLKLFS 1394
+ KG +G+GAFG VY C AVK IE ++ VK +E I +F+ ++RI++Y+G I+T+D H+ IFMEYL GS+ + IK+ +L +YS+QILEG+ +LH N I+HRDIK NIL N+K+ DFG S+ L+T + T + GTP + APEV G Y AD+WS+G TV+ M+T +PP+ D P A KI T + +LP +S + EF+ L + R +A +LL+ +
Sbjct: 4 WRKGKLLGAGAFGQVYMCHDLDTGRELAVKQIETGQLNSSTKNEVKALEGEI-EFMKAFRNERIVQYYG-IETDDLHIYIFMEYLPGGSIHEHIKQHGALNESLTRKYSRQILEGILYLHTNRIVHRDIKGANILRDLYGNVKLADFGASKR-LQTIRSKTGFRSVHGTPYWMAPEVI----NGEGYGRKADVWSVGCTVVEMLTTKPPWADFEPMAALFKIATQPTEPELPS--DLSVDAVEFVRSTLRMNSKSRPSADELLRFSFVT 263
BLAST of Protein kinase domain-containing protein vs. Ensembl Nematostella
Match: EDO42845 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S0A9]) HSP 1 Score: 150.599 bits (379), Expect = 6.403e-41 Identity = 96/271 (35.42%), Postives = 143/271 (52.77%), Query Frame = 3
Query: 579 RLCNTSLRK---KTFDKGSEIGSGAFGHVYKCKGSGIDTVFAVKWIELKKIGVKCIEENINKFLPKLNHQRIIKYFGAIQTEDHLCIFMEYLSAGSLEDEIK-RKRSLATENIIRYSKQILEGLEFLHGNNIIHRDIKPDNILMSNGNNIKITDFGVSRSLLRTCGNVTKAETTIGTPNFTAPEVFLTSDEGPPYTVSADIWSLGATVINMITGRPPYCDCHPFAVPVKIVTTKKLDLPDSQSMSKEMKEFIDKMLDPDPDQRSTAAQLLK 1379
+L SL + + FD ++G G++G V+K V A+K + + + I+E + + + ++KY+G+ L I MEY AGS+ D +K R ++L E I K L+GLE+LH IHRDIK NIL+++ + K+ DFGV+ L T + K T IGTP + APEV + Y ADIWSLG T + M G+PPY D HP I T D S++ K+F+ K L +P++R+TA +LL+
Sbjct: 10 KLSEESLTRPPEEVFDVLEKLGEGSYGSVFKAMHKESGQVVAIKQVPVDTDLQEIIKEI--SMMQQCDSPYVVKYYGSYFKNTDLWIVMEYCGAGSVSDLMKIRNKTLTEEEIKCVLKYTLKGLEYLHLRRKIHRDIKAGNILLNSEGHAKLADFGVAGQLTDT---MAKRNTVIGTPFWMAPEVI----QEVGYDCLADIWSLGITAMEMAEGKPPYADIHPMRAIFMIPTKPPPTFRDPGQWSEDFKDFVSKCLVKNPEERATATELLQ 271
BLAST of Protein kinase domain-containing protein vs. Ensembl Nematostella
Match: EDO40961 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S5T6]) HSP 1 Score: 144.436 bits (363), Expect = 7.935e-39 Identity = 94/266 (35.34%), Postives = 138/266 (51.88%), Query Frame = 3
Query: 612 FDKGSEIGSGAFGHVYKCKGSGIDTVFAVKWIELKKIGVKCIEENINKFLPKLNHQRIIKYFGAI------QTEDHLCIFMEYLSAGSLEDEIK--RKRSLATENIIRYSKQILEGLEFLHGNNIIHRDIKPDNILMSNGNNIKITDFGVSRSLLRTCGNVTKAETTIGTPNFTAPEVFLTSDEGP--PYTVSADIWSLGATVINMITGRPPYCDCHPFAVPVKIVTTKKLDLPDSQSMSKEMKEFIDKMLDPDPDQRSTAAQLLK 1379
FD +G+G +G V+K + + A+K +++ + + I+ IN NH+ I Y+GA +D L + ME+ AGS+ D +K R ++L E I +++L G+ LH N++IHRDIK N+L++ +K+ DFGVS L RT G + T IGTP + APEV + DE P Y D+WS+G T I M +PP CD HP I + L +S SK F++ L D R TA QLL+
Sbjct: 20 FDLVEVVGNGTYGQVHKGRHKRTGQLTAIKIMDVTEDEEEEIKLEINVLRKFSNHRNIATYYGAFIKKSLQGQDDQLWLVMEFCGAGSVTDLVKTARNKALKEEWISYICREVLNGVSHLHMNHVIHRDIKGQNVLLTESAEVKLVDFGVSAQLDRTIG---RRNTFIGTPYWMAPEV-IACDEQPDATYDNRCDMWSIGITAIEMAESQPPLCDMHPMRALFLIPRSDPPKLKSKKSWSKRFHHFVNTCLIKDYQHRPTADQLLQ 281
BLAST of Protein kinase domain-containing protein vs. Ensembl Nematostella
Match: EDO47821 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RL88]) HSP 1 Score: 143.28 bits (360), Expect = 9.675e-39 Identity = 91/276 (32.97%), Postives = 138/276 (50.00%), Query Frame = 3
Query: 612 FDKGSEIGSGAFGHVYKCKGSGIDTVFAVKWIELKKIGVKCIEENINKF------LPKLNHQRIIKYFGAIQTEDHLC---IFMEYLSAGSLEDEIKRKRSLATENIIRYSKQILEGLEFLHGNNIIHRDIKPDNILMSNGNNIKITDFGVSRSLLRTCGNVTKA---ETTIGTPNFTAPEVFLTSDEGPPYTVSADIWSLGATVINMITGRPPYCDCHPFAVPVKIVTTKKLDLPDSQSMSKEMKEFIDKMLDPDPDQRSTAAQLLKLKLFSEFH 1403
+ KG+ +G GAFG V+ + AVK +EL V E K L L H+ I++Y G +D C IFME++ GS+ +KR + RY++QIL+G+ +LH NN+IHRDIK NI++ IK+ DFG ++ + +V+K+ + GTP + APEV + G +DIWS+G TV M TG+PP+ + P + I + D +S S +F+ + D D R +A +LL+ E H
Sbjct: 5 WQKGNVLGKGAFGTVF-LGLVNTGELIAVKQVELHPNNVDAAERQYEKLQEEVGLLKSLKHKNIVQYIGTCM-DDSQCTINIFMEFVPGGSIAQALKRFGAFVEPVFRRYTRQILDGVSYLHNNNVIHRDIKGGNIMLMPNGVIKLIDFGCAKKICMVGAHVSKSNILRSMRGTPYWMAPEVIRETGHGR----KSDIWSIGCTVFEMATGQPPWSNVPPLSAIFAIGNGSPVPRLD-ESFSAAAIDFVTSCMTRDQDTRPSADELLRHDFLQEPH 273
BLAST of Protein kinase domain-containing protein vs. Ensembl Nematostella
Match: EDO31934 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SWI4]) HSP 1 Score: 141.354 bits (355), Expect = 6.744e-37 Identity = 95/261 (36.40%), Postives = 137/261 (52.49%), Query Frame = 3
Query: 603 KKTFDKGSEIGSGAFGHVYKCKGSGIDTVFAVKWIELKKIGVKCI--EENINKFLPKLNHQRIIKYFGAIQTEDHLCIFMEYLSAGSLEDEIKRKRSLATENIIRYSKQILEGLEFLHGNNIIHRDIKPDNILMSNGNNIKITDFGVSRSLLRTCGNVTKAETTIGTPNFTAPEVFLTSDEGPPYTVSADIWSLGATVINMITGRPPYCDCHPFAVPVKIVTTKKLDLPDSQSMSKEMKEFIDKMLDPDPDQRSTAAQLLK 1379
+K F K IG G+FG V+K + + V A+K I+L++ + ++ I L + + + KY G+ L I MEYL GS D +K ++ I +++L+GL++LH +HRDIK N+LMS ++K+ DFGV+ L T + K T +GTP + APEV S Y ADIWSLG T I + G PP D HP V I +L + + SK KEF+ L+ DP+ R TA +LLK
Sbjct: 8 EKLFSKLERIGKGSFGEVFKGIDNRTNEVVAIKIIDLEEAEDEIEDIQQEIT-VLSQCDSLYVTKYHGSYLKGTKLWIIMEYLGGGSALDLMKAG-NIEEFYIATILREVLKGLDYLHTEKKLHRDIKAANVLMSETGDVKLADFGVAGQLTDT---LNKRNTFVGTPFWMAPEVIKQS----AYDSKADIWSLGITAIELAKGEPPNSDLHPMRVLFLIPKNNPPEL--TGNFSKAFKEFVSLCLNKDPNDRPTAKELLK 257
BLAST of Protein kinase domain-containing protein vs. Ensembl Medaka
Match: map3k3 (mitogen-activated protein kinase kinase kinase 3 [Source:NCBI gene;Acc:101169290]) HSP 1 Score: 163.696 bits (413), Expect = 5.691e-43 Identity = 100/266 (37.59%), Postives = 150/266 (56.39%), Query Frame = 3
Query: 609 TFDKGSEIGSGAFGHVYKCKGSGIDTVFAVKWIELKKIG------VKCIEENINKFLPKLNHQRIIKYFGAIQ--TEDHLCIFMEYLSAGSLEDEIKRKRSLATENIIR-YSKQILEGLEFLHGNNIIHRDIKPDNILMSNGNNIKITDFGVSRSLLRTCGNVTKAETTIGTPNFTAPEVFLTSDEGPPYTVSADIWSLGATVINMITGRPPYCDCHPFAVPVKIVTTKKLDLPDSQSMSKEMKEFIDKMLDPDPDQRSTAAQLLK 1379
T+ +G +G GAFG VY C A K ++ V +E I + L L+H+RI++Y+G ++ +E L IFMEY+ GS++D++K +L TEN+ R Y++QILEG+ +LH N I+HRDIK NIL + N+K+ DFG S+ L C + T + GTP + +PEV S EG Y AD+WSLG TV+ M+T +PP+ + A KI T L S + S + ++FI + + R +A +LL+
Sbjct: 352 TWRRGKLLGQGAFGLVYLCYDVDTGRELAAKQVQFDPDSPETSKEVSALECEI-QLLKNLHHERIVQYYGCLRDHSEKTLTIFMEYMPGGSVKDQLKAYGAL-TENVTRKYTRQILEGMSYLHSNMIVHRDIKGANILRDSAGNVKLGDFGASKRLQTICMSGTGIRSVTGTPYWMSPEVI--SGEG--YGRKADVWSLGCTVVEMLTEKPPWAEYEAMAAIFKIATQPTNPLLPSHT-SDQARDFIHCIF-VEAKHRPSAEELLR 609
BLAST of Protein kinase domain-containing protein vs. Ensembl Medaka
Match: map3k2 (mitogen-activated protein kinase kinase kinase 2 [Source:NCBI gene;Acc:101160297]) HSP 1 Score: 160.999 bits (406), Expect = 7.828e-42 Identity = 102/263 (38.78%), Postives = 150/263 (57.03%), Query Frame = 3
Query: 621 GSEIGSGAFGHVYKCKGSGIDTVFAVKWIELKKIG------VKCIEENINKFLPKLNHQRIIKYFGAIQ--TEDHLCIFMEYLSAGSLEDEIKRKRSLATENIIR-YSKQILEGLEFLHGNNIIHRDIKPDNILMSNGNNIKITDFGVSRSLLRTCGNVTKAETTIGTPNFTAPEVFLTSDEGPPYTVSADIWSLGATVINMITGRPPYCDCHPFAVPVKIVTTK-KLDLPDSQSMSKEMKEFIDKMLDPDPDQRSTAAQLLK 1379
G +G GAFG VY C + AVK ++ V +E I + L L H+RI++Y+G ++ E L IFME++ GS++D++K +L TEN+ R Y++QILEG+ +LH N I+HRDIK NIL + N+K+ DFG SR L C + T ++ GTP + +PEV S EG Y ADIWS+G TV+ M+T RPP+ + A KI T +LP +S +EF+ ++ + QR +A +LL+
Sbjct: 392 GKLLGQGAFGRVYLCYDADTGRELAVKQVQFDPESPETSKEVSALECEI-QLLKNLCHERIVQYYGCLRDTMERTLSIFMEHMPGGSIKDQLKSYGAL-TENVTRRYTRQILEGVSYLHSNMIVHRDIKGANILRDSVGNVKLGDFGASRRLQTICLSGTGIKSVTGTPYWMSPEVI--SGEG--YGRKADIWSVGCTVVEMLTQRPPWAEFEAMAAIFKIATQPTNPELP--VHVSDHCREFLRRIFV-ETKQRPSADELLR 645
BLAST of Protein kinase domain-containing protein vs. Ensembl Medaka
Match: stk3 (serine/threonine-protein kinase 3 [Source:NCBI gene;Acc:101155570]) HSP 1 Score: 150.599 bits (379), Expect = 5.505e-39 Identity = 98/277 (35.38%), Postives = 143/277 (51.62%), Query Frame = 3
Query: 579 RLCNTSLRKK---TFDKGSEIGSGAFGHVYKCKGSGIDTVFAVKWIELKKIGVKCIEENINKFLPKLNHQRIIKYFGAIQTEDHLCIFMEYLSAGSLEDEIK-RKRSLATENIIRYSKQILEGLEFLHGNNIIHRDIKPDNILMSNGNNIKITDFGVSRSLLRTCGNVTKAETTIGTPNFTAPEVFLTSDEGPPYTVSADIWSLGATVINMITGRPPYCDCHPFAVPVKIVTTKKLDLPDSQSMSKEMKEFIDKMLDPDPDQRSTAAQLLKLKLFSE 1397
+L SL K+ FD ++G G++G V+K V A+K + ++ + I+E + + + ++KY+G+ L I MEY AGS+ D I+ R ++L + I K L+GLE+LH IHRDIK NIL++ + K+ DFGV+ L T + K T IGTP + APEV + Y ADIWSLG T I M G+PPY D HP I T + S + +F+ K L +P+QR+TA QLL+ S+
Sbjct: 13 KLSEDSLTKQPEEVFDVLEKLGEGSYGSVFKAIHKESGQVVAIKQVPVESDLQEIIKEI--SIMQQCDSPYVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILKSTLKGLEYLHFMRKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDT---MAKRNTVIGTPFWMAPEVI----QEIGYNCVADIWSLGITSIEMAEGKPPYADIHPMRAIFMIPTNPPPTFRKPELWSDDFTDFVKKCLVKNPEQRATATQLLQHPFISQ 280
BLAST of Protein kinase domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000044704.1 (serine/threonine-protein kinase 4 [Source:NCBI gene;Acc:101175466]) HSP 1 Score: 149.828 bits (377), Expect = 7.151e-39 Identity = 94/271 (34.69%), Postives = 140/271 (51.66%), Query Frame = 3
Query: 579 RLCNTSLRKK---TFDKGSEIGSGAFGHVYKCKGSGIDTVFAVKWIELKKIGVKCIEENINKFLPKLNHQRIIKYFGAIQTEDHLCIFMEYLSAGSLEDEIK-RKRSLATENIIRYSKQILEGLEFLHGNNIIHRDIKPDNILMSNGNNIKITDFGVSRSLLRTCGNVTKAETTIGTPNFTAPEVFLTSDEGPPYTVSADIWSLGATVINMITGRPPYCDCHPFAVPVKIVTTKKLDLPDSQSMSKEMKEFIDKMLDPDPDQRSTAAQLLK 1379
+L SL K+ FD ++G G++G V+K + A+K + ++ + I+E + + N +++Y+G+ L I MEY AGS+ D I+ R ++L+ E I L+GLE+LH IHRDIK NIL++ K+ DFGV+ L T + K T IGTP + APEV + Y ADIWSLG T I M G+PPY D HP I T + S+ ++F+ + L +P+ R+TA QLL+
Sbjct: 19 KLSEDSLTKQPEEVFDVLEKLGEGSYGCVFKANYKETGEIVAIKQVPVESDLQEIIKEI--SIMQQCNSPHVVRYYGSYFKNSDLWIVMEYCGAGSVSDIIRIRNKTLSEEEIATVVHSTLKGLEYLHFMRKIHRDIKAGNILLNAEGQAKLADFGVAGQLTDT---MAKRNTVIGTPFWMAPEVI----QEIGYNCVADIWSLGITAIEMAEGKPPYADIHPMRAIFMIPTNPPPTFRNPDLWSENFRDFVSQCLVKNPENRATATQLLQ 280
BLAST of Protein kinase domain-containing protein vs. Ensembl Medaka
Match: stk3 (serine/threonine-protein kinase 3 [Source:NCBI gene;Acc:101155570]) HSP 1 Score: 149.443 bits (376), Expect = 1.424e-38 Identity = 95/270 (35.19%), Postives = 140/270 (51.85%), Query Frame = 3
Query: 591 TSLRKKTFDKGSEIGSGAFGHVYKCKGSGIDTVFAVKWIELKKIGVKCIEENINKFLPKLNHQRIIKYFGAIQTEDHLCIFMEYLSAGSLEDEIK-RKRSLATENIIRYSKQILEGLEFLHGNNIIHRDIKPDNILMSNGNNIKITDFGVSRSLLRTCGNVTKAETTIGTPNFTAPEVFLTSDEGPPYTVSADIWSLGATVINMITGRPPYCDCHPFAVPVKIVTTKKLDLPDSQSMSKEMKEFIDKMLDPDPDQRSTAAQLLKLKLFSE 1397
T ++ FD ++G G++G V+K V A+K + ++ + I+E + + + ++KY+G+ L I MEY AGS+ D I+ R ++L + I K L+GLE+LH IHRDIK NIL++ + K+ DFGV+ L T + K T IGTP + APEV + Y ADIWSLG T I M G+PPY D HP I T + S + +F+ K L +P+QR+TA QLL+ S+
Sbjct: 23 TKQPEEVFDVLEKLGEGSYGSVFKAIHKESGQVVAIKQVPVESDLQEIIKEI--SIMQQCDSPYVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILKSTLKGLEYLHFMRKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDT---MAKRNTVIGTPFWMAPEVI----QEIGYNCVADIWSLGITSIEMAEGKPPYADIHPMRAIFMIPTNPPPTFRKPELWSDDFTDFVKKCLVKNPEQRATATQLLQHPFISQ 283
BLAST of Protein kinase domain-containing protein vs. Planmine SMEST
Match: SMESG000017261.1 (SMESG000017261.1) HSP 1 Score: 725.317 bits (1871), Expect = 0.000e+0 Identity = 371/382 (97.12%), Postives = 373/382 (97.64%), Query Frame = 3
Query: 264 PCLLRACKNGDLKKVSTLLNGAAIEYCDKDQRRPIHWACESGNIKVVKSLIKTKCDISARDKYNLSPLDIAIKNQNXXXXXXXXXXXXXXXXXMMGLKCKSFCNHRLCNTSLRKKTFDKGSEIGSGAFGHVYKCKGSGIDTVFAVKWIELKKIGVKCIEENINKFLPKLNHQRIIKYFGAIQTEDHLCIFMEYLSAGSLEDEIKRKRSLATENIIRYSKQILEGLEFLHGNNIIHRDIKPDNILMSNGNNIKITDFGVSRSLLRTCGNVTKAETTIGTPNFTAPEVFLTSDEGPPYTVSADIWSLGATVINMITGRPPYCDCHPFAVPVKIVTTKKLDLPDSQSMSKEMKEFIDKMLDPDPDQRSTAAQLLKLKLFSEFHQD 1409
PCLLRACKNGDLKKVST LNGAAIEYCDKDQRRPIHWACESGNIKVVKSLIKTKCDISARDK NLSPLDIAIKNQNKELVELLKAEELEQQILMMGLKCKSFCNHRLCNTSLRKKTFDKGSEIGSGAFGHVYKCKGSGIDTVFAVKWIELKKIGVKCIEENINKFLPKLNHQRIIKYFGAIQTEDHLCIFMEYLS GSLEDEIKRKRSLATENIIRYSKQILEGLEFLHGNNIIHRDIKPDNILMSNGNNIKITDFGVSRSLLRTCGNVTKAETTIGTPNFTAPEVFLTSDEGPPYTVSADIWSLGATVINMITGRPPYC CHP+AV KI TKKLDLPDSQSMSKEMKEFI+KMLDPDPDQRSTAAQLLKLKLFSEF QD
Sbjct: 190 PCLLRACKNGDLKKVSTYLNGAAIEYCDKDQRRPIHWACESGNIKVVKSLIKTKCDISARDKSNLSPLDIAIKNQNKELVELLKAEELEQQILMMGLKCKSFCNHRLCNTSLRKKTFDKGSEIGSGAFGHVYKCKGSGIDTVFAVKWIELKKIGVKCIEENINKFLPKLNHQRIIKYFGAIQTEDHLCIFMEYLSGGSLEDEIKRKRSLATENIIRYSKQILEGLEFLHGNNIIHRDIKPDNILMSNGNNIKITDFGVSRSLLRTCGNVTKAETTIGTPNFTAPEVFLTSDEGPPYTVSADIWSLGATVINMITGRPPYCGCHPYAVVKKIADTKKLDLPDSQSMSKEMKEFIEKMLDPDPDQRSTAAQLLKLKLFSEFDQD 571 HSP 2 Score: 57.3806 bits (137), Expect = 2.328e-8 Identity = 31/72 (43.06%), Postives = 45/72 (62.50%), Query Frame = 3
Query: 279 ACKNGDLKKVSTLL-NGAAIEYCDKDQRRPIHWACESGNIKVVKSLIKTKCDISARDKYNLSPLDIAIKNQN 491
AC G + V L+ + IE D+ +RPIH AC+ G+ + VK LI+ KCDI A D+ SP++IA+K+ N
Sbjct: 109 ACYQGRSEAVKLLIEHKCDIEAIDEWNQRPIHHACDQGHSEAVKLLIENKCDIEALDESGDSPMEIAVKSHN 180 HSP 3 Score: 50.0618 bits (118), Expect = 4.138e-6 Identity = 29/68 (42.65%), Postives = 38/68 (55.88%), Query Frame = 3
Query: 276 RACKNGDLKKVSTLL-NGAAIEYCDKDQRRPIHWACESGNIKVVKSLIKTKCDISARDKYNLSPLDIA 476
AC G + V L+ + IE DK RPIH+AC G+ + VK LI+ KCDI A D +N P+ A
Sbjct: 42 HACFAGHAEIVKLLIEHNCDIEALDKWNLRPIHYACYQGHSEAVKLLIEHKCDIEAFDWWNQRPIHYA 109 HSP 4 Score: 49.2914 bits (116), Expect = 7.975e-6 Identity = 28/67 (41.79%), Postives = 38/67 (56.72%), Query Frame = 3
Query: 279 ACKNGDLKKVSTLL-NGAAIEYCDKDQRRPIHWACESGNIKVVKSLIKTKCDISARDKYNLSPLDIA 476
AC G + V L+ + IE D +RPIH+AC G + VK LI+ KCDI A D++N P+ A
Sbjct: 76 ACYQGHSEAVKLLIEHKCDIEAFDWWNQRPIHYACYQGRSEAVKLLIEHKCDIEAIDEWNQRPIHHA 142 HSP 5 Score: 48.9062 bits (115), Expect = 9.896e-6 Identity = 26/69 (37.68%), Postives = 36/69 (52.17%), Query Frame = 3
Query: 270 LLRACKNGDLKKVSTLLNGAAIEYCDKDQRRPIHWACESGNIKVVKSLIKTKCDISARDKYNLSPLDIA 476
+ A K+G +E D D PIH AC +G+ ++VK LI+ CDI A DK+NL P+ A
Sbjct: 8 FINAIKSGSAVLFRRYFKEEYLERKDADLWSPIHHACFAGHAEIVKLLIEHNCDIEALDKWNLRPIHYA 76
BLAST of Protein kinase domain-containing protein vs. Planmine SMEST
Match: SMESG000017261.1 (SMESG000017261.1) HSP 1 Score: 724.931 bits (1870), Expect = 0.000e+0 Identity = 371/382 (97.12%), Postives = 373/382 (97.64%), Query Frame = 3
Query: 264 PCLLRACKNGDLKKVSTLLNGAAIEYCDKDQRRPIHWACESGNIKVVKSLIKTKCDISARDKYNLSPLDIAIKNQNXXXXXXXXXXXXXXXXXMMGLKCKSFCNHRLCNTSLRKKTFDKGSEIGSGAFGHVYKCKGSGIDTVFAVKWIELKKIGVKCIEENINKFLPKLNHQRIIKYFGAIQTEDHLCIFMEYLSAGSLEDEIKRKRSLATENIIRYSKQILEGLEFLHGNNIIHRDIKPDNILMSNGNNIKITDFGVSRSLLRTCGNVTKAETTIGTPNFTAPEVFLTSDEGPPYTVSADIWSLGATVINMITGRPPYCDCHPFAVPVKIVTTKKLDLPDSQSMSKEMKEFIDKMLDPDPDQRSTAAQLLKLKLFSEFHQD 1409
PCLLRACKNGDLKKVST LNGAAIEYCDKDQRRPIHWACESGNIKVVKSLIKTKCDISARDK NLSPLDIAIKNQNKELVELLKAEELEQQILMMGLKCKSFCNHRLCNTSLRKKTFDKGSEIGSGAFGHVYKCKGSGIDTVFAVKWIELKKIGVKCIEENINKFLPKLNHQRIIKYFGAIQTEDHLCIFMEYLS GSLEDEIKRKRSLATENIIRYSKQILEGLEFLHGNNIIHRDIKPDNILMSNGNNIKITDFGVSRSLLRTCGNVTKAETTIGTPNFTAPEVFLTSDEGPPYTVSADIWSLGATVINMITGRPPYC CHP+AV KI TKKLDLPDSQSMSKEMKEFI+KMLDPDPDQRSTAAQLLKLKLFSEF QD
Sbjct: 256 PCLLRACKNGDLKKVSTYLNGAAIEYCDKDQRRPIHWACESGNIKVVKSLIKTKCDISARDKSNLSPLDIAIKNQNKELVELLKAEELEQQILMMGLKCKSFCNHRLCNTSLRKKTFDKGSEIGSGAFGHVYKCKGSGIDTVFAVKWIELKKIGVKCIEENINKFLPKLNHQRIIKYFGAIQTEDHLCIFMEYLSGGSLEDEIKRKRSLATENIIRYSKQILEGLEFLHGNNIIHRDIKPDNILMSNGNNIKITDFGVSRSLLRTCGNVTKAETTIGTPNFTAPEVFLTSDEGPPYTVSADIWSLGATVINMITGRPPYCGCHPYAVVKKIADTKKLDLPDSQSMSKEMKEFIEKMLDPDPDQRSTAAQLLKLKLFSEFDQD 637 HSP 2 Score: 57.3806 bits (137), Expect = 2.521e-8 Identity = 31/72 (43.06%), Postives = 45/72 (62.50%), Query Frame = 3
Query: 279 ACKNGDLKKVSTLL-NGAAIEYCDKDQRRPIHWACESGNIKVVKSLIKTKCDISARDKYNLSPLDIAIKNQN 491
AC G + V L+ + IE D+ +RPIH AC+ G+ + VK LI+ KCDI A D+ SP++IA+K+ N
Sbjct: 175 ACYQGRSEAVKLLIEHKCDIEAIDEWNQRPIHHACDQGHSEAVKLLIENKCDIEALDESGDSPMEIAVKSHN 246 HSP 3 Score: 53.9138 bits (128), Expect = 2.802e-7 Identity = 30/67 (44.78%), Postives = 38/67 (56.72%), Query Frame = 3
Query: 279 ACKNGDLKKVSTLL-NGAAIEYCDKDQRRPIHWACESGNIKVVKSLIKTKCDISARDKYNLSPLDIA 476
AC G + V L+ + IE DK RRPIH AC G+ + VK LI+ CDI A D +NL P+ A
Sbjct: 76 ACDQGRSEAVKLLIEHKCDIEALDKRNRRPIHLACYQGHSEAVKLLIEHNCDIEALDVWNLRPIHYA 142 HSP 4 Score: 53.1434 bits (126), Expect = 5.170e-7 Identity = 30/68 (44.12%), Postives = 39/68 (57.35%), Query Frame = 3
Query: 276 RACKNGDLKKVSTLL-NGAAIEYCDKDQRRPIHWACESGNIKVVKSLIKTKCDISARDKYNLSPLDIA 476
AC G + V L+ + IE DK +RPIH AC+ G + VK LI+ KCDI A DK N P+ +A
Sbjct: 42 HACFAGHAEIVKLLIEHNCDIEALDKRNQRPIHLACDQGRSEAVKLLIEHKCDIEALDKRNRRPIHLA 109 HSP 5 Score: 48.9062 bits (115), Expect = 9.355e-6 Identity = 28/67 (41.79%), Postives = 38/67 (56.72%), Query Frame = 3
Query: 279 ACKNGDLKKVSTLL-NGAAIEYCDKDQRRPIHWACESGNIKVVKSLIKTKCDISARDKYNLSPLDIA 476
AC G + V L+ + IE D +RPIH+AC G + VK LI+ KCDI A D++N P+ A
Sbjct: 142 ACYQGHSEAVKLLIEHKCDIEAFDWWNQRPIHYACYQGRSEAVKLLIEHKCDIEAIDEWNQRPIHHA 208
BLAST of Protein kinase domain-containing protein vs. Planmine SMEST
Match: SMESG000017261.1 (SMESG000017261.1) HSP 1 Score: 724.546 bits (1869), Expect = 0.000e+0 Identity = 371/382 (97.12%), Postives = 373/382 (97.64%), Query Frame = 3
Query: 264 PCLLRACKNGDLKKVSTLLNGAAIEYCDKDQRRPIHWACESGNIKVVKSLIKTKCDISARDKYNLSPLDIAIKNQNXXXXXXXXXXXXXXXXXMMGLKCKSFCNHRLCNTSLRKKTFDKGSEIGSGAFGHVYKCKGSGIDTVFAVKWIELKKIGVKCIEENINKFLPKLNHQRIIKYFGAIQTEDHLCIFMEYLSAGSLEDEIKRKRSLATENIIRYSKQILEGLEFLHGNNIIHRDIKPDNILMSNGNNIKITDFGVSRSLLRTCGNVTKAETTIGTPNFTAPEVFLTSDEGPPYTVSADIWSLGATVINMITGRPPYCDCHPFAVPVKIVTTKKLDLPDSQSMSKEMKEFIDKMLDPDPDQRSTAAQLLKLKLFSEFHQD 1409
PCLLRACKNGDLKKVST LNGAAIEYCDKDQRRPIHWACESGNIKVVKSLIKTKCDISARDK NLSPLDIAIKNQNKELVELLKAEELEQQILMMGLKCKSFCNHRLCNTSLRKKTFDKGSEIGSGAFGHVYKCKGSGIDTVFAVKWIELKKIGVKCIEENINKFLPKLNHQRIIKYFGAIQTEDHLCIFMEYLS GSLEDEIKRKRSLATENIIRYSKQILEGLEFLHGNNIIHRDIKPDNILMSNGNNIKITDFGVSRSLLRTCGNVTKAETTIGTPNFTAPEVFLTSDEGPPYTVSADIWSLGATVINMITGRPPYC CHP+AV KI TKKLDLPDSQSMSKEMKEFI+KMLDPDPDQRSTAAQLLKLKLFSEF QD
Sbjct: 355 PCLLRACKNGDLKKVSTYLNGAAIEYCDKDQRRPIHWACESGNIKVVKSLIKTKCDISARDKSNLSPLDIAIKNQNKELVELLKAEELEQQILMMGLKCKSFCNHRLCNTSLRKKTFDKGSEIGSGAFGHVYKCKGSGIDTVFAVKWIELKKIGVKCIEENINKFLPKLNHQRIIKYFGAIQTEDHLCIFMEYLSGGSLEDEIKRKRSLATENIIRYSKQILEGLEFLHGNNIIHRDIKPDNILMSNGNNIKITDFGVSRSLLRTCGNVTKAETTIGTPNFTAPEVFLTSDEGPPYTVSADIWSLGATVINMITGRPPYCGCHPYAVVKKIADTKKLDLPDSQSMSKEMKEFIEKMLDPDPDQRSTAAQLLKLKLFSEFDQD 736 HSP 2 Score: 56.9954 bits (136), Expect = 3.071e-8 Identity = 31/72 (43.06%), Postives = 45/72 (62.50%), Query Frame = 3
Query: 279 ACKNGDLKKVSTLL-NGAAIEYCDKDQRRPIHWACESGNIKVVKSLIKTKCDISARDKYNLSPLDIAIKNQN 491
AC G + V L+ + IE D+ +RPIH AC+ G+ + VK LI+ KCDI A D+ SP++IA+K+ N
Sbjct: 274 ACYQGRSEAVKLLIEHKCDIEAIDEWNQRPIHHACDQGHSEAVKLLIENKCDIEALDESGDSPMEIAVKSHN 345 HSP 3 Score: 53.5286 bits (127), Expect = 4.097e-7 Identity = 30/67 (44.78%), Postives = 38/67 (56.72%), Query Frame = 3
Query: 279 ACKNGDLKKVSTLL-NGAAIEYCDKDQRRPIHWACESGNIKVVKSLIKTKCDISARDKYNLSPLDIA 476
AC +G + V L+ N IE D RRPIH AC G+ + VK LI+ CDI A D +NL P+ A
Sbjct: 175 ACYHGHSEAVKLLIENKCDIEALDWRNRRPIHLACYQGHSEAVKLLIEHNCDIEALDVWNLRPIHYA 241 HSP 4 Score: 52.7582 bits (125), Expect = 6.353e-7 Identity = 30/68 (44.12%), Postives = 39/68 (57.35%), Query Frame = 3
Query: 276 RACKNGDLKKVSTLL-NGAAIEYCDKDQRRPIHWACESGNIKVVKSLIKTKCDISARDKYNLSPLDIA 476
AC G + V L+ + IE DK +RPIH AC+ G + VK LI+ KCDI A DK N P+ +A
Sbjct: 42 HACFAGHAEIVKLLIEHNCDIEALDKRNQRPIHLACDQGRSEAVKLLIEHKCDIEALDKRNQRPIHLA 109 HSP 5 Score: 52.373 bits (124), Expect = 8.659e-7 Identity = 30/67 (44.78%), Postives = 37/67 (55.22%), Query Frame = 3
Query: 279 ACKNGDLKKVSTLL-NGAAIEYCDKDQRRPIHWACESGNIKVVKSLIKTKCDISARDKYNLSPLDIA 476
AC G + V L+ N IE D +RPIH AC G+ K VK LI KCDI A D +N P+ +A
Sbjct: 109 ACDQGHSEAVKLLIENKCDIEALDWGNQRPIHLACYYGHSKAVKLLIDHKCDIEALDWWNQRPIHLA 175 HSP 6 Score: 51.6026 bits (122), Expect = 1.366e-6 Identity = 29/67 (43.28%), Postives = 39/67 (58.21%), Query Frame = 3
Query: 279 ACKNGDLKKVSTLL-NGAAIEYCDKDQRRPIHWACESGNIKVVKSLIKTKCDISARDKYNLSPLDIA 476
AC G + V L+ + IE DK +RPIH AC+ G+ + VK LI+ KCDI A D N P+ +A
Sbjct: 76 ACDQGRSEAVKLLIEHKCDIEALDKRNQRPIHLACDQGHSEAVKLLIENKCDIEALDWGNQRPIHLA 142 HSP 7 Score: 48.9062 bits (115), Expect = 9.859e-6 Identity = 28/67 (41.79%), Postives = 38/67 (56.72%), Query Frame = 3
Query: 279 ACKNGDLKKVSTLL-NGAAIEYCDKDQRRPIHWACESGNIKVVKSLIKTKCDISARDKYNLSPLDIA 476
AC G + V L+ + IE D +RPIH+AC G + VK LI+ KCDI A D++N P+ A
Sbjct: 241 ACYQGHSEAVKLLIEHKCDIEAFDWWNQRPIHYACYQGRSEAVKLLIEHKCDIEAIDEWNQRPIHHA 307
BLAST of Protein kinase domain-containing protein vs. Planmine SMEST
Match: SMESG000032703.1 (SMESG000032703.1) HSP 1 Score: 578.941 bits (1491), Expect = 0.000e+0 Identity = 300/381 (78.74%), Postives = 330/381 (86.61%), Query Frame = 3
Query: 270 LLRACKNGDLKKVSTLLNGAAIEYCDKDQRRPIHWACESGNIKVVKSLIKTKCDISARDKYNLSPLDIAIKNQNXXXXXXXXXXXXXXXXXMMGLKCKS-FCNHRLCNTSLRKKTFDKGSEIGSGAFGHVYKCKGSGIDTVFAVKWIELKKIGVKCIEENINKFLPKLNHQRIIKYFGAIQTEDHLCIFMEYLSAGSLEDEIKRKRSLATENIIRYSKQILEGLEFLHGNNIIHRDIKPDNILMSNGNNIKITDFGVSRSLLRTCGNVTKAETTIGTPNFTAPEVFLTSDEGPPYTVSADIWSLGATVINMITGRPPYCDCHPFAVPVKIVTTKKLDLPDSQSMSKEMKEFIDKMLDPDPDQRSTAAQLLKLKLFSEFHQD 1409
LL ACK GD KKVS LLN IEYCDK +RRPIHWACESGNIK+VKSLIKTKCDI+A+DK NL PLDIAIK +NKELVE+LK EELEQQI MMGL+CK FCNHRLC TSL+ KTF KGSEIGSG FGH+YKCKGSGIDTVFA+KWIEL KI K IEENIN FLPKL H+RII+YFGAIQT+DHLCIFMEYL GSLEDEI++KR +AT+NIIRYSKQILEGLEFLHGN IIHRDIKP NILM NNIK+ DFG+SRSL+RTCG +TKA TTIGTPNFTAPEV LTSD GPPYT SADIWS+GATVINMITGRPPY CHPFAV +I T+KKL+LP+S+ MS MK FI++ML+PDPDQRSTAAQLLKLK FSEF D
Sbjct: 535 LLLACKTGDTKKVSRLLNSITIEYCDKGKRRPIHWACESGNIKIVKSLIKTKCDITAKDKDNLRPLDIAIKKENKELVEILKEEELEQQISMMGLECKPPFCNHRLCKTSLKNKTFAKGSEIGSGGFGHIYKCKGSGIDTVFAIKWIELIKISEKYIEENINTFLPKLMHKRIIRYFGAIQTKDHLCIFMEYLFKGSLEDEIEKKRFIATKNIIRYSKQILEGLEFLHGNRIIHRDIKPANILMGPENNIKLADFGISRSLMRTCGEITKAVTTIGTPNFTAPEVILTSDNGPPYTESADIWSMGATVINMITGRPPYYYCHPFAVINRISTSKKLELPESELMSDAMKGFIEEMLNPDPDQRSTAAQLLKLKFFSEFDFD 915 HSP 2 Score: 57.7658 bits (138), Expect = 2.240e-8 Identity = 28/73 (38.36%), Postives = 48/73 (65.75%), Query Frame = 3
Query: 276 RACKNGDLKKVSTLLNGAA-IEYCDKDQRRPIHWACESGNIKVVKSLIKTKCDISARDKYNLSPLDIAIKNQN 491
AC++G ++ V L++ I+ D++ +PIH AC +GNI+ +K LI C+I A DK+ SP++IA+++ N
Sbjct: 451 HACRSGHIETVKLLIDHHCDIDASDRNDWQPIHHACVAGNIETLKLLIDHYCNIEALDKFGDSPIEIAVRSCN 523 HSP 3 Score: 53.9138 bits (128), Expect = 3.287e-7 Identity = 27/67 (40.30%), Postives = 41/67 (61.19%), Query Frame = 3
Query: 279 ACKNGDLKKVSTLL-NGAAIEYCDKDQRRPIHWACESGNIKVVKSLIKTKCDISARDKYNLSPLDIA 476
AC G ++ V L+ + IE D++ RPIH+AC +G++K+VK LI CDI A D + P+ +A
Sbjct: 221 ACSAGHIEAVKLLIYHHCDIEALDQNDWRPIHYACCAGHMKIVKLLIDYHCDIDASDTNDWRPIHLA 287 HSP 4 Score: 50.0618 bits (118), Expect = 5.333e-6 Identity = 27/69 (39.13%), Postives = 41/69 (59.42%), Query Frame = 3
Query: 279 ACKNGDLKKVSTLLN-GAAIEYCDKDQRRPIHWACESGNIKVVKSLIKTKCDISARDKYNLSPLDIAIK 482
AC G +K V L++ I+ D + RPIH AC +G+I++VK LI CDI+A D + P+ A++
Sbjct: 254 ACCAGHMKIVKLLIDYHCDIDASDTNDWRPIHLACGAGHIEIVKLLIDYHCDINASDMNDNRPIHFALR 322
BLAST of Protein kinase domain-containing protein vs. Planmine SMEST
Match: SMESG000017030.1 (SMESG000017030.1) HSP 1 Score: 529.25 bits (1362), Expect = 0.000e+0 Identity = 274/378 (72.49%), Postives = 315/378 (83.33%), Query Frame = 3
Query: 270 LLRACKNGDLKKVSTLLNGAAIEYCDKDQRRPIHWACESGNIKVVKSLIKTKCDISARDKYNLSPLDIAIKNQNXXXXXXXXXXXXXXXXXMMGLKCKSFCNHRLCNTSLRKKTFDKGSEIGSGAFGHVYKCKGSGIDTVFAVKWIELKKIGVKCIEENINKFLPKLNHQRIIKYFGAIQTEDHLCIFMEYLSAGSLEDEI-KRKRSLATENIIRYSKQILEGLEFLHGNNIIHRDIKPDNILMSNGNNIKITDFGVSRSLLRTCGNVTKAETTIGTPNFTAPEVFLTSDEGPPYTVSADIWSLGATVINMITGRPPYCDCHPFAVPVKIVTTKKLDLPDSQSMSKEMKEFIDKMLDPDPDQRSTAAQLLKLKLFSEF 1400
LL ACKNGDLK VS L+NG+ IE CDK++RRPIHWACESGNI++VK LI+ KCD++ARDK +SPLDIA+KN+NKELVE+LKAEELE I MGLKCK FC+H+ CNTSLR KTF KGS IG+GAFG +YKCKGSGID VFA+KWIELKKIG K IE NIN+FL KLNH+RIIKYFGAIQ +DHLCIFMEYLS GSLEDEI KRKR + TEN I+YSKQILEGLEFLH + IIHRDIKP NIL+S+ NNIK+ DFG+SRSL+RT G TKA + +GT NFTAPEV + PYT SADIWS+GATVINMI GRPPY C P A+ KI T KKL +P SQ MS+EMK FI++ML+PDP++R TAAQLLKLKLFSEF
Sbjct: 354 LLLACKNGDLKNVSKLVNGSTIECCDKNKRRPIHWACESGNIEIVKLLIERKCDLTARDKCEMSPLDIAVKNENKELVEILKAEELELLISKMGLKCKLFCDHKFCNTSLRNKTFVKGSHIGNGAFGDIYKCKGSGIDAVFAIKWIELKKIGEKSIEGNINQFLHKLNHKRIIKYFGAIQAKDHLCIFMEYLSKGSLEDEIIKRKRPIDTENTIKYSKQILEGLEFLHSHRIIHRDIKPANILLSDENNIKLADFGISRSLMRTDGKSTKAVSGVGTFNFTAPEVIRIEIDNAPYTESADIWSVGATVINMIEGRPPYDYCDPLALIFKIATDKKLVMPHSQMMSEEMKAFIEEMLNPDPNKRPTAAQLLKLKLFSEF 731 HSP 2 Score: 55.8398 bits (133), Expect = 7.187e-8 Identity = 28/72 (38.89%), Postives = 44/72 (61.11%), Query Frame = 3
Query: 279 ACKNGDLKKVSTLL-NGAAIEYCDKDQRRPIHWACESGNIKVVKSLIKTKCDISARDKYNLSPLDIAIKNQN 491
AC +G + V L+ + IE D+D RPIH+AC G+ + +K LI+ +C+I A DK+N P+ AI ++
Sbjct: 106 ACNHGHSEAVKLLIEHKCDIEALDEDNWRPIHYACNHGHSEAIKLLIEHECNIEALDKWNQRPIHYAINKRH 177 HSP 3 Score: 50.447 bits (119), Expect = 3.420e-6 Identity = 27/67 (40.30%), Postives = 39/67 (58.21%), Query Frame = 3
Query: 279 ACKNGDLKKVSTLL-NGAAIEYCDKDQRRPIHWACESGNIKVVKSLIKTKCDISARDKYNLSPLDIA 476
AC +G + V L+ + IE D ++RPIH AC G+ + VK L + KCDI A D +N P+ +A
Sbjct: 205 ACNHGHSEAVKLLIEHKCDIEALDWQKQRPIHLACNHGHSEAVKLLTEHKCDIEALDIWNQRPIHLA 271 The following BLAST results are available for this feature:
BLAST of Protein kinase domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30018632 ID=SMED30018632|Name=Protein kinase domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=1777bpback to top protein sequence of SMED30018632-orf-1 >SMED30018632-orf-1 ID=SMED30018632-orf-1|Name=SMED30018632-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=290bp MMGLKCKSFCNHRLCNTSLRKKTFDKGSEIGSGAFGHVYKCKGSGIDTVFback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
|
