Calcitonin family peptide receptor

Overview
NameCalcitonin family peptide receptor
Smed IDSMED30018600
Length (bp)1448
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Calcitonin family peptide receptor (SMED30018600) t-SNE clustered cells

Violin plots show distribution of expression levels for Calcitonin family peptide receptor (SMED30018600) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Calcitonin family peptide receptor (SMED30018600) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Calcitonin family peptide receptor (SMED30018600) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30018600

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 9

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
head regionSMED30018600h1SMcG0008487 SmedASXL_009843SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016
whole organism asexual adult RNA-sequencing evidence
nervous systemSMED30018600h1SMcG0008487 dd_Smed_v4_13281_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30018600h1SMcG0008487 dd_Smed_v4_13281_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
muscle cellSMED30018600h1SMcG0008487 dd_Smed_v4_13281_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymaSMED30018600h1SMcG0008487 dd_Smed_v4_13281_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
non-ciliated neuronSMED30018600h1SMcG0008487 dd_Smed_v4_13281_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cilated neuronSMED30018600h1SMcG0008487 dd_Smed_v4_13281_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
head regionSMED30018600h1SMcG0008487 dd_Smed_v6_13281_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017
whole organism asexual adult RNA-sequencing evidence
head regionSMED30018600h1SMcG0008487 OX_Smed_1.0.07072ox_Smed_v2PMID:24238224
Kao et al., 2013
whole organism asexual adult RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of Calcitonin family peptide receptor vs. Ensembl Human
Match: CALCR (calcitonin receptor [Source:HGNC Symbol;Acc:HGNC:1440])

HSP 1 Score: 190.66 bits (483), Expect = 2.234e-54
Identity = 119/376 (31.65%), Postives = 195/376 (51.86%), Query Frame = 3
Query:  162 SCEAQMPPPPPTDGQ-LYCRAIYDGLLCWNYTKAGLTVEQNCPALY-DFNVSALAYKSCLPSGEWLTKGGVNQSYTDYMAC---VPKASYSIYIYF----VGYSMSIIALVISLAVLFYFKQLNCHRITLHKNMFFCNLMNSTGWLLYINVLSMHSNDSAVYS---MCQALYLIVNYTGTATYFWMLCEGLYL-LMILIFTFNKGQFIVRFCIILGWGAPLVIIILFGSLRFSVGASNLCHLDGFNNLMYIMLVPIFVTIIFNMIFMAFILGILFNKFRNHRNIEQHQGQKAAKAILILTPVMGLHSLLLLVQPDDAMWLKVHKYASALTNSLQGFLITMPFCFFNSEIHEAIKMR--RRRLQFTNK-ARLSNSRS 1241
             C  +M   P   G+  YC   +DG LCW+ T AG+   Q CP  + DF+ S    K C   G W      N+++++Y  C    P+   + Y+ +    VG+S+SI  LVISL +  +F+ L C R+TLHKNMF   ++NS   ++ I+++ +  N   V      C+ L+    Y     YFWMLCEG+YL  +I++  F + Q + R+  +LGWG PLV   +    R +V  ++ C L    +L+YI+  P+   ++ N  F+  I+ +L  K R     E H   KA KA +IL P++G+  ++   +P + M  K++ Y        QGF +   +CF N+E+   +K +  + ++Q+  +  R  ++RS
Sbjct:   54 KCYDRMQQLPAYQGEGPYCNRTWDGWLCWDDTPAGVLSYQFCPDYFPDFDPSEKVTKYCDEKGVWFKHPENNRTWSNYTMCNAFTPEKLKNAYVLYYLAIVGHSLSIFTLVISLGIFVFFRSLGCQRVTLHKNMFLTYILNSM--IIIIHLVEVVPNGELVRRDPVSCKILHFFHQYMMACNYFWMLCEGIYLHTLIVVAVFTEKQRL-RWYYLLGWGFPLVPTTIHAITR-AVYFNDNCWLSVETHLLYIIHGPVMAALVVNFFFLLNIVRVLVTKMRETHEAESHMYLKAVKATMILVPLLGIQFVVFPWRPSNKMLGKIYDYVMHSLIHFQGFFVATIYCFCNNEVQTTVKRQWAQFKIQWNQRWGRRPSNRS 425          
BLAST of Calcitonin family peptide receptor vs. Ensembl Human
Match: CALCR (calcitonin receptor [Source:HGNC Symbol;Acc:HGNC:1440])

HSP 1 Score: 190.66 bits (483), Expect = 2.234e-54
Identity = 119/376 (31.65%), Postives = 195/376 (51.86%), Query Frame = 3
Query:  162 SCEAQMPPPPPTDGQ-LYCRAIYDGLLCWNYTKAGLTVEQNCPALY-DFNVSALAYKSCLPSGEWLTKGGVNQSYTDYMAC---VPKASYSIYIYF----VGYSMSIIALVISLAVLFYFKQLNCHRITLHKNMFFCNLMNSTGWLLYINVLSMHSNDSAVYS---MCQALYLIVNYTGTATYFWMLCEGLYL-LMILIFTFNKGQFIVRFCIILGWGAPLVIIILFGSLRFSVGASNLCHLDGFNNLMYIMLVPIFVTIIFNMIFMAFILGILFNKFRNHRNIEQHQGQKAAKAILILTPVMGLHSLLLLVQPDDAMWLKVHKYASALTNSLQGFLITMPFCFFNSEIHEAIKMR--RRRLQFTNK-ARLSNSRS 1241
             C  +M   P   G+  YC   +DG LCW+ T AG+   Q CP  + DF+ S    K C   G W      N+++++Y  C    P+   + Y+ +    VG+S+SI  LVISL +  +F+ L C R+TLHKNMF   ++NS   ++ I+++ +  N   V      C+ L+    Y     YFWMLCEG+YL  +I++  F + Q + R+  +LGWG PLV   +    R +V  ++ C L    +L+YI+  P+   ++ N  F+  I+ +L  K R     E H   KA KA +IL P++G+  ++   +P + M  K++ Y        QGF +   +CF N+E+   +K +  + ++Q+  +  R  ++RS
Sbjct:   54 KCYDRMQQLPAYQGEGPYCNRTWDGWLCWDDTPAGVLSYQFCPDYFPDFDPSEKVTKYCDEKGVWFKHPENNRTWSNYTMCNAFTPEKLKNAYVLYYLAIVGHSLSIFTLVISLGIFVFFRSLGCQRVTLHKNMFLTYILNSM--IIIIHLVEVVPNGELVRRDPVSCKILHFFHQYMMACNYFWMLCEGIYLHTLIVVAVFTEKQRL-RWYYLLGWGFPLVPTTIHAITR-AVYFNDNCWLSVETHLLYIIHGPVMAALVVNFFFLLNIVRVLVTKMRETHEAESHMYLKAVKATMILVPLLGIQFVVFPWRPSNKMLGKIYDYVMHSLIHFQGFFVATIYCFCNNEVQTTVKRQWAQFKIQWNQRWGRRPSNRS 425          
BLAST of Calcitonin family peptide receptor vs. Ensembl Human
Match: CALCR (calcitonin receptor [Source:HGNC Symbol;Acc:HGNC:1440])

HSP 1 Score: 181.03 bits (458), Expect = 1.101e-50
Identity = 119/392 (30.36%), Postives = 196/392 (50.00%), Query Frame = 3
Query:  162 SCEAQMPPPPPTDGQ-LYCRAIYDGLLCWNYTKAGLTVEQNCPALY-DFNVSALAYKSCLPSGEWLTKGGVNQSYTDYMAC---VPKASYSIYIYF----VGYSMSIIALVISLAVLFYFKQLN----------------CHRITLHKNMFFCNLMNSTGWLLYINVLSMHSNDSAVYS---MCQALYLIVNYTGTATYFWMLCEGLYL-LMILIFTFNKGQFIVRFCIILGWGAPLVIIILFGSLRFSVGASNLCHLDGFNNLMYIMLVPIFVTIIFNMIFMAFILGILFNKFRNHRNIEQHQGQKAAKAILILTPVMGLHSLLLLVQPDDAMWLKVHKYASALTNSLQGFLITMPFCFFNSEIHEAIKMR--RRRLQFTNK-ARLSNSRS 1241
             C  +M   P   G+  YC   +DG LCW+ T AG+   Q CP  + DF+ S    K C   G W      N+++++Y  C    P+   + Y+ +    VG+S+SI  LVISL +  +F++L                 C R+TLHKNMF   ++NS   ++ I+++ +  N   V      C+ L+    Y     YFWMLCEG+YL  +I++  F + Q + R+  +LGWG PLV   +    R +V  ++ C L    +L+YI+  P+   ++ N  F+  I+ +L  K R     E H   KA KA +IL P++G+  ++   +P + M  K++ Y        QGF +   +CF N+E+   +K +  + ++Q+  +  R  ++RS
Sbjct:   54 KCYDRMQQLPAYQGEGPYCNRTWDGWLCWDDTPAGVLSYQFCPDYFPDFDPSEKVTKYCDEKGVWFKHPENNRTWSNYTMCNAFTPEKLKNAYVLYYLAIVGHSLSIFTLVISLGIFVFFRKLTTIFPLNWKYRKALSLGCQRVTLHKNMFLTYILNSM--IIIIHLVEVVPNGELVRRDPVSCKILHFFHQYMMACNYFWMLCEGIYLHTLIVVAVFTEKQRL-RWYYLLGWGFPLVPTTIHAITR-AVYFNDNCWLSVETHLLYIIHGPVMAALVVNFFFLLNIVRVLVTKMRETHEAESHMYLKAVKATMILVPLLGIQFVVFPWRPSNKMLGKIYDYVMHSLIHFQGFFVATIYCFCNNEVQTTVKRQWAQFKIQWNQRWGRRPSNRS 441          
BLAST of Calcitonin family peptide receptor vs. Ensembl Human
Match: CALCR (calcitonin receptor [Source:HGNC Symbol;Acc:HGNC:1440])

HSP 1 Score: 181.415 bits (459), Expect = 1.238e-50
Identity = 119/392 (30.36%), Postives = 196/392 (50.00%), Query Frame = 3
Query:  162 SCEAQMPPPPPTDGQ-LYCRAIYDGLLCWNYTKAGLTVEQNCPALY-DFNVSALAYKSCLPSGEWLTKGGVNQSYTDYMAC---VPKASYSIYIYF----VGYSMSIIALVISLAVLFYFKQLN----------------CHRITLHKNMFFCNLMNSTGWLLYINVLSMHSNDSAVYS---MCQALYLIVNYTGTATYFWMLCEGLYL-LMILIFTFNKGQFIVRFCIILGWGAPLVIIILFGSLRFSVGASNLCHLDGFNNLMYIMLVPIFVTIIFNMIFMAFILGILFNKFRNHRNIEQHQGQKAAKAILILTPVMGLHSLLLLVQPDDAMWLKVHKYASALTNSLQGFLITMPFCFFNSEIHEAIKMR--RRRLQFTNK-ARLSNSRS 1241
             C  +M   P   G+  YC   +DG LCW+ T AG+   Q CP  + DF+ S    K C   G W      N+++++Y  C    P+   + Y+ +    VG+S+SI  LVISL +  +F++L                 C R+TLHKNMF   ++NS   ++ I+++ +  N   V      C+ L+    Y     YFWMLCEG+YL  +I++  F + Q + R+  +LGWG PLV   +    R +V  ++ C L    +L+YI+  P+   ++ N  F+  I+ +L  K R     E H   KA KA +IL P++G+  ++   +P + M  K++ Y        QGF +   +CF N+E+   +K +  + ++Q+  +  R  ++RS
Sbjct:   72 KCYDRMQQLPAYQGEGPYCNRTWDGWLCWDDTPAGVLSYQFCPDYFPDFDPSEKVTKYCDEKGVWFKHPENNRTWSNYTMCNAFTPEKLKNAYVLYYLAIVGHSLSIFTLVISLGIFVFFRKLTTIFPLNWKYRKALSLGCQRVTLHKNMFLTYILNSM--IIIIHLVEVVPNGELVRRDPVSCKILHFFHQYMMACNYFWMLCEGIYLHTLIVVAVFTEKQRL-RWYYLLGWGFPLVPTTIHAITR-AVYFNDNCWLSVETHLLYIIHGPVMAALVVNFFFLLNIVRVLVTKMRETHEAESHMYLKAVKATMILVPLLGIQFVVFPWRPSNKMLGKIYDYVMHSLIHFQGFFVATIYCFCNNEVQTTVKRQWAQFKIQWNQRWGRRPSNRS 459          
BLAST of Calcitonin family peptide receptor vs. Ensembl Human
Match: CALCRL (calcitonin receptor like receptor [Source:HGNC Symbol;Acc:HGNC:16709])

HSP 1 Score: 179.104 bits (453), Expect = 3.380e-50
Identity = 121/390 (31.03%), Postives = 197/390 (50.51%), Query Frame = 3
Query:  177 MPPPPPTDGQLYCRAIYDGLLCWNYTKAGLTVEQNCPALY-DFNVSALAYKSCLPSGEWLTKGGVNQSYTDYMAC-------VPKASYSIYIYFVGYSMSIIALVISLAVLFYFKQLNCHRITLHKNMFFCNLMNSTGWLLYINVLSMHSNDSAVYSM----CQALYLIVNYTGTATYFWMLCEGLYL-LMILIFTFNKGQFIVRFCIILGWGAPLVIIILFGSLRFSVGASNLCHLDGFNNLMYIMLVPIFVTIIFNMIFMAFILGILFNKFRNHRNIEQHQGQKAAKAILILTPVMGLHSLLLLVQPDDAMWLKVHKYASALTNSLQGFLITMPFCFFNSEIHEAIKM--RRRRLQFTNKARLSNSRSKNIPRVRTPQTSLALGKSYE 1301
            M  P      +YC   +DG LCWN   AG    Q CP  + DF+ S    K C   G W      N+++T+Y  C       V  A    Y+  +G+ +SI +L+ISL + FYFK L+C RITLHKN+FF  + NS   ++++  ++   N+ A+ +     C+    I  Y     YFWMLCEG+YL  +I++  F + Q ++ +   LGWG PL+   +    R S+  ++ C +    +L+YI+  PI   ++ N+ F+  I+ +L  K +     E +   KA +A LIL P++G+  +L+  +P+  +  +V+ Y   +    QG L++  FCFFN E+   ++    + ++QF N    SNS +           S   G S++
Sbjct:   53 MQDPIQQAEGVYCNRTWDGWLCWNDVAAGTESMQLCPDYFQDFDPSEKVTKICDQDGNWFRHPASNRTWTNYTQCNVNTHEKVKTALNLFYLTIIGHGLSIASLLISLGIFFYFKSLSCQRITLHKNLFFSFVCNSVVTIIHLTAVA---NNQALVATNPVSCKVSQFIHLYLMGCNYFWMLCEGIYLHTLIVVAVFAEKQHLMWY-YFLGWGFPLIPACIHAIAR-SLYYNDNCWISSDTHLLYIIHGPICAALLVNLFFLLNIVRVLITKLKVTHQAESNLYMKAVRATLILVPLLGIEFVLIPWRPEGKIAEEVYDYIMHILMHFQGLLVSTIFCFFNGEVQAILRRNWNQYKIQFGNS--FSNSEALRSASYTVSTISDGPGYSHD 435          
BLAST of Calcitonin family peptide receptor vs. Ensembl Celegans
Match: pdfr-1 (Calcitonin receptor-like protein 1 [Source:UniProtKB/Swiss-Prot;Acc:Q09460])

HSP 1 Score: 129.413 bits (324), Expect = 2.877e-32
Identity = 100/416 (24.04%), Postives = 190/416 (45.67%), Query Frame = 3
Query:  102 SPSFMSFQNDSFDYLELERTSCEAQM------PPPPPTDGQLYCRAIYDGLLCWNYTKAGLTVEQNCPALYDFNVSALAYKSCLPSGEWLTK---------GGVNQS------YTDYMACVPKASYSIYIYFVGYSMSIIALVISLAVLFYFKQLNCHRITLHKNMFFCNLMNSTGWL-LYINVL-----SMHSNDSAVYSM------CQALYLIVNYTGTATYFWMLCEGLYLLMILIFTFNKGQFIVRFCIILGWGAPLV-----IIILFGSLRFSVGASNLCHLDGFNNLMYIMLVPIFVTIIFNMIFMAFILGILFNKFRNHRNIEQHQGQKAAKAILILTPVMGLHSLLLLV----QPDDAMWLKVHKYASALTNSLQGFLITMPFCFFNSEIHEAIKMRRRRLQFTNKAR 1223
            S S  +F N++ D LE     C+  +      P   P D +++C A YD +LCW  T A  +V   CP +   + +    K C  +G W  K         G  N +      Y D       A  +  + FVG  +S+++L++++++  YF++L   R  LH ++    LM     L LYI+++       H+N +   ++      C+ ++  + Y  T T+ WM  EG+YL   ++F F   +  +    I G+G PLV     ++++     F V      +        +I+  P    ++ N+ F+  ++ +L++K R   N  +   +K+ KA ++L P++G+ +++  +      D+ M   V  Y ++ T   QG ++   +CF N E++  +K    R +  +K++
Sbjct:   32 STSVQAF-NEAMDVLEESYPLCKKMLDHNNLFPERDPNDTRIWCNATYDTVLCWPPTPANSSVTLQCPHMKGLDPNKYIVKRCDETGRWAGKKPGHYENPWGWTNFTVCFKIDYEDAKIAQEVARNARKLEFVGLGLSLVSLILAISIFSYFRRLRVFRNLLHLHLMIAMLMVVILRLVLYIDLIFTGENGPHTNSAEGKTINTMPIVCEGMFFFLEYFKTVTFCWMFLEGIYLNNQIVFGFFNSEPKLLPYFIAGYGIPLVHTMLWLLVVLIKKDFKVERCLGSYY--LEPEFWILDGPRMAELVINLFFICNVIRVLYSKVRESNNTSEAGLKKSVKAAMMLLPLLGVPNIMQTIPFAPTRDNIMVFAVWTYTASFTYMYQGLMVASIYCFTNKEVNHVLKTFYARYRLLHKSQ 444          
BLAST of Calcitonin family peptide receptor vs. Ensembl Celegans
Match: pdfr-1 (Calcitonin receptor-like protein 1 [Source:UniProtKB/Swiss-Prot;Acc:Q09460])

HSP 1 Score: 129.413 bits (324), Expect = 2.877e-32
Identity = 100/416 (24.04%), Postives = 190/416 (45.67%), Query Frame = 3
Query:  102 SPSFMSFQNDSFDYLELERTSCEAQM------PPPPPTDGQLYCRAIYDGLLCWNYTKAGLTVEQNCPALYDFNVSALAYKSCLPSGEWLTK---------GGVNQS------YTDYMACVPKASYSIYIYFVGYSMSIIALVISLAVLFYFKQLNCHRITLHKNMFFCNLMNSTGWL-LYINVL-----SMHSNDSAVYSM------CQALYLIVNYTGTATYFWMLCEGLYLLMILIFTFNKGQFIVRFCIILGWGAPLV-----IIILFGSLRFSVGASNLCHLDGFNNLMYIMLVPIFVTIIFNMIFMAFILGILFNKFRNHRNIEQHQGQKAAKAILILTPVMGLHSLLLLV----QPDDAMWLKVHKYASALTNSLQGFLITMPFCFFNSEIHEAIKMRRRRLQFTNKAR 1223
            S S  +F N++ D LE     C+  +      P   P D +++C A YD +LCW  T A  +V   CP +   + +    K C  +G W  K         G  N +      Y D       A  +  + FVG  +S+++L++++++  YF++L   R  LH ++    LM     L LYI+++       H+N +   ++      C+ ++  + Y  T T+ WM  EG+YL   ++F F   +  +    I G+G PLV     ++++     F V      +        +I+  P    ++ N+ F+  ++ +L++K R   N  +   +K+ KA ++L P++G+ +++  +      D+ M   V  Y ++ T   QG ++   +CF N E++  +K    R +  +K++
Sbjct:   32 STSVQAF-NEAMDVLEESYPLCKKMLDHNNLFPERDPNDTRIWCNATYDTVLCWPPTPANSSVTLQCPHMKGLDPNKYIVKRCDETGRWAGKKPGHYENPWGWTNFTVCFKIDYEDAKIAQEVARNARKLEFVGLGLSLVSLILAISIFSYFRRLRVFRNLLHLHLMIAMLMVVILRLVLYIDLIFTGENGPHTNSAEGKTINTMPIVCEGMFFFLEYFKTVTFCWMFLEGIYLNNQIVFGFFNSEPKLLPYFIAGYGIPLVHTMLWLLVVLIKKDFKVERCLGSYY--LEPEFWILDGPRMAELVINLFFICNVIRVLYSKVRESNNTSEAGLKKSVKAAMMLLPLLGVPNIMQTIPFAPTRDNIMVFAVWTYTASFTYMYQGLMVASIYCFTNKEVNHVLKTFYARYRLLHKSQ 444          
BLAST of Calcitonin family peptide receptor vs. Ensembl Celegans
Match: pdfr-1 (Calcitonin receptor-like protein 1 [Source:UniProtKB/Swiss-Prot;Acc:Q09460])

HSP 1 Score: 129.028 bits (323), Expect = 4.737e-32
Identity = 100/416 (24.04%), Postives = 189/416 (45.43%), Query Frame = 3
Query:  102 SPSFMSFQNDSFDYLELERTSCEAQM------PPPPPTDGQLYCRAIYDGLLCWNYTKAGLTVEQNCPALYDFNVSALAYKSCLPSGEWLTK---------GGVN------QSYTDYMACVPKASYSIYIYFVGYSMSIIALVISLAVLFYFKQLNCHRITLHKNMFFCNLMNSTGWL-LYINVL-----SMHSNDSAVYSM------CQALYLIVNYTGTATYFWMLCEGLYLLMILIFTFNKGQFIVRFCIILGWGAPLV-----IIILFGSLRFSVGASNLCHLDGFNNLMYIMLVPIFVTIIFNMIFMAFILGILFNKFRNHRNIEQHQGQKAAKAILILTPVMGLHSLLLLV----QPDDAMWLKVHKYASALTNSLQGFLITMPFCFFNSEIHEAIKMRRRRLQFTNKAR 1223
            S S  +F N++ D LE     C+  +      P   P D +++C A YD +LCW  T A  +V   CP +   + +    K C  +G W  K         G  N        Y D       A  +  + FVG  +S+++L++++++  YF++L   R  LH ++    LM     L LYI+++       H+N +   ++      C+ ++  + Y  T T+ WM  EG+YL   ++F F   +  +    I G+G PLV     ++++     F V      +        +I+  P    ++ N+ F+  ++ +L++K R   N  +   +K+ KA ++L P++G+ +++  +      D+ M   V  Y ++ T   QG ++   +CF N E++  +K    R +  +K++
Sbjct:   32 STSVQAF-NEAMDVLEESYPLCKKMLDHNNLFPERDPNDTRIWCNATYDTVLCWPPTPANSSVTLQCPHMKGLDPNKYIVKRCDETGRWAGKKPGHYENPWGWTNFTVCFKIDYEDAKIAQEVARNARKLEFVGLGLSLVSLILAISIFSYFRRLRVFRNLLHLHLMIAMLMVVILRLVLYIDLIFTGENGPHTNSAEGKTINTMPIVCEGMFFFLEYFKTVTFCWMFLEGIYLNNQIVFGFFNSEPKLLPYFIAGYGIPLVHTMLWLLVVLIKKDFKVERCLGSYY--LEPEFWILDGPRMAELVINLFFICNVIRVLYSKVRESNNTSEAGLKKSVKAAMMLLPLLGVPNIMQTIPFAPTRDNIMVFAVWTYTASFTYMYQGLMVASIYCFTNKEVNHVLKTFYARYRLLHKSQ 444          
BLAST of Calcitonin family peptide receptor vs. Ensembl Celegans
Match: pdfr-1 (Calcitonin receptor-like protein 1 [Source:UniProtKB/Swiss-Prot;Acc:Q09460])

HSP 1 Score: 129.028 bits (323), Expect = 4.737e-32
Identity = 100/416 (24.04%), Postives = 189/416 (45.43%), Query Frame = 3
Query:  102 SPSFMSFQNDSFDYLELERTSCEAQM------PPPPPTDGQLYCRAIYDGLLCWNYTKAGLTVEQNCPALYDFNVSALAYKSCLPSGEWLTK---------GGVN------QSYTDYMACVPKASYSIYIYFVGYSMSIIALVISLAVLFYFKQLNCHRITLHKNMFFCNLMNSTGWL-LYINVL-----SMHSNDSAVYSM------CQALYLIVNYTGTATYFWMLCEGLYLLMILIFTFNKGQFIVRFCIILGWGAPLV-----IIILFGSLRFSVGASNLCHLDGFNNLMYIMLVPIFVTIIFNMIFMAFILGILFNKFRNHRNIEQHQGQKAAKAILILTPVMGLHSLLLLV----QPDDAMWLKVHKYASALTNSLQGFLITMPFCFFNSEIHEAIKMRRRRLQFTNKAR 1223
            S S  +F N++ D LE     C+  +      P   P D +++C A YD +LCW  T A  +V   CP +   + +    K C  +G W  K         G  N        Y D       A  +  + FVG  +S+++L++++++  YF++L   R  LH ++    LM     L LYI+++       H+N +   ++      C+ ++  + Y  T T+ WM  EG+YL   ++F F   +  +    I G+G PLV     ++++     F V      +        +I+  P    ++ N+ F+  ++ +L++K R   N  +   +K+ KA ++L P++G+ +++  +      D+ M   V  Y ++ T   QG ++   +CF N E++  +K    R +  +K++
Sbjct:   32 STSVQAF-NEAMDVLEESYPLCKKMLDHNNLFPERDPNDTRIWCNATYDTVLCWPPTPANSSVTLQCPHMKGLDPNKYIVKRCDETGRWAGKKPGHYENPWGWTNFTVCFKIDYEDAKIAQEVARNARKLEFVGLGLSLVSLILAISIFSYFRRLRVFRNLLHLHLMIAMLMVVILRLVLYIDLIFTGENGPHTNSAEGKTINTMPIVCEGMFFFLEYFKTVTFCWMFLEGIYLNNQIVFGFFNSEPKLLPYFIAGYGIPLVHTMLWLLVVLIKKDFKVERCLGSYY--LEPEFWILDGPRMAELVINLFFICNVIRVLYSKVRESNNTSEAGLKKSVKAAMMLLPLLGVPNIMQTIPFAPTRDNIMVFAVWTYTASFTYMYQGLMVASIYCFTNKEVNHVLKTFYARYRLLHKSQ 444          
BLAST of Calcitonin family peptide receptor vs. Ensembl Celegans
Match: pdfr-1 (Calcitonin receptor-like protein 1 [Source:UniProtKB/Swiss-Prot;Acc:Q09460])

HSP 1 Score: 129.028 bits (323), Expect = 4.767e-32
Identity = 97/408 (23.77%), Postives = 186/408 (45.59%), Query Frame = 3
Query:  126 NDSFDYLELERTSCEAQM------PPPPPTDGQLYCRAIYDGLLCWNYTKAGLTVEQNCPALYDFNVSALAYKSCLPSGEWLTK---------GGVNQS------YTDYMACVPKASYSIYIYFVGYSMSIIALVISLAVLFYFKQLNCHRITLHKNMFFCNLMNSTGWL-LYINVL-----SMHSNDSAVYSM------CQALYLIVNYTGTATYFWMLCEGLYLLMILIFTFNKGQFIVRFCIILGWGAPLV-----IIILFGSLRFSVGASNLCHLDGFNNLMYIMLVPIFVTIIFNMIFMAFILGILFNKFRNHRNIEQHQGQKAAKAILILTPVMGLHSLLLLV----QPDDAMWLKVHKYASALTNSLQGFLITMPFCFFNSEIHEAIKMRRRRLQFTNKAR 1223
            N++ D LE     C+  +      P   P D +++C A YD +LCW  T A  +V   CP +   + +    K C  +G W  K         G  N +      Y D       A  +  + FVG  +S+++L++++++  YF++L   R  LH ++    LM     L LYI+++       H+N +   ++      C+ ++  + Y  T T+ WM  EG+YL   ++F F   +  +    I G+G PLV     ++++     F V      +        +I+  P    ++ N+ F+  ++ +L++K R   N  +   +K+ KA ++L P++G+ +++  +      D+ M   V  Y ++ T   QG ++   +CF N E++  +K    R +  +K++
Sbjct:   39 NEAMDVLEESYPLCKKMLDHNNLFPERDPNDTRIWCNATYDTVLCWPPTPANSSVTLQCPHMKGLDPNKYIVKRCDETGRWAGKKPGHYENPWGWTNFTVCFKIDYEDAKIAQEVARNARKLEFVGLGLSLVSLILAISIFSYFRRLRVFRNLLHLHLMIAMLMVVILRLVLYIDLIFTGENGPHTNSAEGKTINTMPIVCEGMFFFLEYFKTVTFCWMFLEGIYLNNQIVFGFFNSEPKLLPYFIAGYGIPLVHTMLWLLVVLIKKDFKVERCLGSYY--LEPEFWILDGPRMAELVINLFFICNVIRVLYSKVRESNNTSEAGLKKSVKAAMMLLPLLGVPNIMQTIPFAPTRDNIMVFAVWTYTASFTYMYQGLMVASIYCFTNKEVNHVLKTFYARYRLLHKSQ 444          
BLAST of Calcitonin family peptide receptor vs. Ensembl Fly
Match: hec (gene:FBgn0030437 transcript:FBtr0343652)

HSP 1 Score: 156.762 bits (395), Expect = 4.003e-42
Identity = 111/347 (31.99%), Postives = 185/347 (53.31%), Query Frame = 3
Query:  198 DGQLYCRAIYDGLLCWNYTKAGLTVEQNCPALYD-FNVSALAYKSCLPSGEWLTKGGVNQSYTDYMACVPKASYSIY-----IYFVGYSMSIIALVISLAVLFYFKQLNCHRITLHKNMFFCNLMNSTGWLLYINVLSMHSNDSAVYSM-CQALYLIVNYTGTATYFWMLCEGLYLLMILIFTFNKGQFIVRFCIILGWGAPLVIIILFGSLR-FSVGASNLCHLDGFNNLMYIMLVPIFVTIIFNMIFMAFILGILFNKFRNHRNIEQHQG---QKAAKAILILTPVMGLHSLLLLVQPDDAMWLK-VHKYASALTNSLQGFLITMPFCFFNSEIHEAIKMRRRRL 1202
            + +L+C   +DG LCW  T AG  + Q CP   + FN   LA+K+CL +G W      NQ++++Y  CV             +Y  GY++S++AL+IS+ +   FK L C RI +H ++F         W+L+  ++   S   A   + C  L+L+V+Y     YFWM CEGL+L ++L+  F K   ++R+ I++ W +P+ I I++G  R FS   +  C +   +  ++I  VPI ++++ + IF+  +L ++  K   H    Q      +KA +A +IL P+ GL   LL  +PD    L   ++  S +  SLQGF+++  FCF N ++  AI+    +L
Sbjct:  115 ENRLFCPLNFDGYLCWPRTPAGTVLSQYCPDFVEGFNRKFLAHKTCLENGSWYRHPVSNQTWSNYTNCVDYEDLEFRQFINELYVKGYALSLLALLISIIIFLGFKSLRCTRIRIHVHLFASLACTCVAWILWYRLVVERSETIAENPLWCIGLHLVVHYFMLVNYFWMFCEGLHLHLVLVVVFVKDTIVMRWFIVISWFSPIPIAIVYGLARHFSSPDNKHCWITD-SLYLWIFSVPITLSLLASFIFLINVLRVIVRKL--HPQSAQPAPLAIRKAVRATIILVPLFGLQHFLLPYRPDAGTQLDHFYQMLSVVLVSLQGFVVSFLFCFANHDVTFAIRTLLNKL 458          
BLAST of Calcitonin family peptide receptor vs. Ensembl Fly
Match: hec (gene:FBgn0030437 transcript:FBtr0073753)

HSP 1 Score: 156.762 bits (395), Expect = 4.003e-42
Identity = 111/347 (31.99%), Postives = 185/347 (53.31%), Query Frame = 3
Query:  198 DGQLYCRAIYDGLLCWNYTKAGLTVEQNCPALYD-FNVSALAYKSCLPSGEWLTKGGVNQSYTDYMACVPKASYSIY-----IYFVGYSMSIIALVISLAVLFYFKQLNCHRITLHKNMFFCNLMNSTGWLLYINVLSMHSNDSAVYSM-CQALYLIVNYTGTATYFWMLCEGLYLLMILIFTFNKGQFIVRFCIILGWGAPLVIIILFGSLR-FSVGASNLCHLDGFNNLMYIMLVPIFVTIIFNMIFMAFILGILFNKFRNHRNIEQHQG---QKAAKAILILTPVMGLHSLLLLVQPDDAMWLK-VHKYASALTNSLQGFLITMPFCFFNSEIHEAIKMRRRRL 1202
            + +L+C   +DG LCW  T AG  + Q CP   + FN   LA+K+CL +G W      NQ++++Y  CV             +Y  GY++S++AL+IS+ +   FK L C RI +H ++F         W+L+  ++   S   A   + C  L+L+V+Y     YFWM CEGL+L ++L+  F K   ++R+ I++ W +P+ I I++G  R FS   +  C +   +  ++I  VPI ++++ + IF+  +L ++  K   H    Q      +KA +A +IL P+ GL   LL  +PD    L   ++  S +  SLQGF+++  FCF N ++  AI+    +L
Sbjct:  115 ENRLFCPLNFDGYLCWPRTPAGTVLSQYCPDFVEGFNRKFLAHKTCLENGSWYRHPVSNQTWSNYTNCVDYEDLEFRQFINELYVKGYALSLLALLISIIIFLGFKSLRCTRIRIHVHLFASLACTCVAWILWYRLVVERSETIAENPLWCIGLHLVVHYFMLVNYFWMFCEGLHLHLVLVVVFVKDTIVMRWFIVISWFSPIPIAIVYGLARHFSSPDNKHCWITD-SLYLWIFSVPITLSLLASFIFLINVLRVIVRKL--HPQSAQPAPLAIRKAVRATIILVPLFGLQHFLLPYRPDAGTQLDHFYQMLSVVLVSLQGFVVSFLFCFANHDVTFAIRTLLNKL 458          
BLAST of Calcitonin family peptide receptor vs. Ensembl Fly
Match: Dh31-R (gene:FBgn0052843 transcript:FBtr0087755)

HSP 1 Score: 152.91 bits (385), Expect = 5.223e-41
Identity = 118/401 (29.43%), Postives = 204/401 (50.87%), Query Frame = 3
Query:  132 SFDYLELERTSCEAQMPPP--------PPTDGQLYCRAIYDGLLCWNYTKAGLTVEQNCPA-LYDFNVSALAYKSCLPSGEWLTKGGVNQSYTDYMACVPKASYSIY-----IYFVGYSMSIIALVISLAVLFYFKQLNCHRITLHKNMFFCNLMNSTGWLLYINVLSMHSNDSAVYSM-CQALYLIVNYTGTATYFWMLCEGLYLLMILIFTFNKGQFIVRFCIILGWGAPLVIIILFGSLRFSVGA---SNLCHLDGFNNLMYIMLVPIFVTIIFNMIFMAFILGILFNKFRNHRNIEQHQGQ-----KAAKAILILTPVMGLHSLLLLVQPDDAM-WLKVHKYASALTNSLQGFLITMPFCFFNSEIHEAIKMRRRRLQFTNKARLSNSRSKNIPRVR 1262
             FD L   R +CE ++           P  +   +C   +DG LCW  T  G +  + CP  +  F+ +  A+K C   GEW      N+++++Y  CV     +       I  VGY  S++A+++SLA+L YFK L C RITLH N+F     N++ WL++  ++  +S       M C AL++ ++Y   + Y WMLCEG YL  +L+  F   + +V++ I  GWG+P ++I ++   R   G    +  C ++   N   I++VP+ +++  N++F+  I+ ++  K     +I+   G      +A +A L+L P++GL  +L   +P     W   ++  SA T S QG  + + FCF N E+   +K + R + F+N+ R ++  +  +  VR
Sbjct:   36 DFDAL---RAACETRLNASGQLAGSGGPGAEAGTHCAGTFDGWLCWPDTAVGTSAYELCPDFITGFDPARYAHKECGLDGEWFKHPLTNKTWSNYTTCVNLEDLNWRHTVNLISEVGYGTSLLAILLSLAILGYFKSLKCARITLHMNLFASFAANNSLWLVWYLLVMPNSELLHQSPMRCVALHITLHYFLLSNYSWMLCEGFYLHTVLVAAFISEKRLVKWLIAFGWGSPAIVIFVYSMARGLGGTPEDNRHCWMNQ-TNYQNILMVPVCISMFLNLLFLCNIVRVVLLKLNAPASIQGSCGPSRTVLQAFRATLLLVPLLGLQYILTPFRPAPKHPWENTYEIISAFTASFQGLCVAILFCFCNGEVIAQMKRKWRMMCFSNRPRTNSYTATQVSFVR 432          
BLAST of Calcitonin family peptide receptor vs. Ensembl Fly
Match: Dh31-R (gene:FBgn0052843 transcript:FBtr0330735)

HSP 1 Score: 151.369 bits (381), Expect = 1.881e-40
Identity = 116/397 (29.22%), Postives = 202/397 (50.88%), Query Frame = 3
Query:  132 SFDYLELERTSCEAQMPPP--------PPTDGQLYCRAIYDGLLCWNYTKAGLTVEQNCPA-LYDFNVSALAYKSCLPSGEWLTKGGVNQSYTDYMACVPKASYSIY-----IYFVGYSMSIIALVISLAVLFYFKQLNCHRITLHKNMFFCNLMNSTGWLLYINVLSMHSNDSAVYSM-CQALYLIVNYTGTATYFWMLCEGLYLLMILIFTFNKGQFIVRFCIILGWGAPLVIIILFGSLRFSVGA---SNLCHLDGFNNLMYIMLVPIFVTIIFNMIFMAFILGILFNKFRNHRNIEQHQGQ-----KAAKAILILTPVMGLHSLLLLVQPDDAM-WLKVHKYASALTNSLQGFLITMPFCFFNSEIHEAIKMRRRRLQFTNKARLSNSRSKNI 1250
             FD L   R +CE ++           P  +   +C   +DG LCW  T  G +  + CP  +  F+ +  A+K C   GEW      N+++++Y  CV     +       I  VGY  S++A+++SLA+L YFK L C RITLH N+F     N++ WL++  ++  +S       M C AL++ ++Y   + Y WMLCEG YL  +L+  F   + +V++ I  GWG+P ++I ++   R   G    +  C ++   N   I++VP+ +++  N++F+  I+ ++  K     +I+   G      +A +A L+L P++GL  +L   +P     W   ++  SA T S QG  + + FCF N E+   +K + R + F+N+ R ++  +  +
Sbjct:   36 DFDAL---RAACETRLNASGQLAGSGGPGAEAGTHCAGTFDGWLCWPDTAVGTSAYELCPDFITGFDPARYAHKECGLDGEWFKHPLTNKTWSNYTTCVNLEDLNWRHTVNLISEVGYGTSLLAILLSLAILGYFKSLKCARITLHMNLFASFAANNSLWLVWYLLVMPNSELLHQSPMRCVALHITLHYFLLSNYSWMLCEGFYLHTVLVAAFISEKRLVKWLIAFGWGSPAIVIFVYSMARGLGGTPEDNRHCWMNQ-TNYQNILMVPVCISMFLNLLFLCNIVRVVLLKLNAPASIQGSCGPSRTVLQAFRATLLLVPLLGLQYILTPFRPAPKHPWENTYEIISAFTASFQGLCVAILFCFCNGEVIAQMKRKWRMMCFSNRPRTNSYTATQV 428          
BLAST of Calcitonin family peptide receptor vs. Ensembl Fly
Match: Dh44-R2 (gene:FBgn0033744 transcript:FBtr0087936)

HSP 1 Score: 150.984 bits (380), Expect = 4.680e-40
Identity = 99/358 (27.65%), Postives = 168/358 (46.93%), Query Frame = 3
Query:  207 LYCRAIYDGLLCWNYTKAGLTVEQNCPALYD---FNVSALAYKSCLPSGEWLTKGGVNQSYTDYMAC-------------VPKASYSIYIYFVGYSMSIIALVISLAVLFYFKQLNCHRITLHKNMFFCNLMNSTGWLL--YINVLSMHSNDSAVYSMCQALYLIVNYTGTATYFWMLCEGLYLLMILIFTFNKGQFIVRFCIILGWGAPLVIIILFGSLRFSVGASNLCHLDG--FNNLM------------YIMLVPIFVTIIFNMIFMAFILGILFNKFRNHRNIEQHQGQKAAKAILILTPVMGLHSLLLLVQPDDAMWLKVHKYASALTNSLQGFLITMPFCFFNSEIHEAIK 1184
            L C + +D +LCW  T AG      C   +    ++ +  A + C P+G W         Y+DY  C              P       IY  GY +S   LV++L +   FK L C R T+H N+F   + ++  W+L  ++ V++  S+ +     C  L ++  Y     +FWM  EGLYL  +++ TF+          ++GWG P V I+++     S+  +   HL+   FN L             +I  VP  + ++ N++F+  I+ +L  K R+   +E  Q  KA+KA+L+L P+ G+  LL+L  P+  +   + +   A   S QGF + + +CF NSE+ + ++
Sbjct:   82 LQCPSSFDSVLCWPRTNAGSLAVLPCFEEFKGVHYDTTDNATRFCFPNGTW-------DHYSDYDRCHQNSGSIPVVPDFSPNVELPAIIYAGGYFLSFATLVVALIIFLSFKDLRCLRNTIHANLFLTYITSALLWILTLFLQVITTESSQAG----CITLVIMFQYFYLTNFFWMFVEGLYLYTLVVQTFSSDNISFIIYALIGWGCPAVCILVW-----SIAKAFAPHLENEHFNGLEIDCAWMRESHIDWIFKVPASLALLVNLVFLIRIMWVLITKLRSAHTLETRQYYKASKALLVLIPLFGITYLLVLTGPEQGISRNLFEAIRAFLISTQGFFVALFYCFLNSEVRQTLR 423          
BLAST of Calcitonin family peptide receptor vs. Ensembl Zebrafish
Match: calcr (calcitonin receptor [Source:ZFIN;Acc:ZDB-GENE-060503-420])

HSP 1 Score: 191.045 bits (484), Expect = 5.294e-54
Identity = 119/379 (31.40%), Postives = 205/379 (54.09%), Query Frame = 3
Query:  189 PPTDGQLYCRAIYDGLLCWNYTKAGLTVEQNCPALY-DFNVSALAYKSCLPSGEWLTKGGVNQSYTDYMACVP------KASYSIY-IYFVGYSMSIIALVISLAVLFYFKQLNCHRITLHKNMFFCNLMNSTGWLLYINVLSMHSNDSAVYS--MCQALYLIVNYTGTATYFWMLCEGLYL-LMILIFTFNKGQFIVRFCIILGWGAPLVIIILFGSLRFSVGASNLCHLDGFNNLMYIMLVPIFVTIIFNMIFMAFILGILFNKFRNHRNIEQHQGQKAAKAILILTPVMGLHSLLLLVQPDDAMWLKVHKYASALTNSLQGFLITMPFCFFNSEIHEAIKMRRRRLQFTNKARLSNSRSKNIPRVRTPQTSLALGK 1292
            P     LYC   +DG LCW+ T AG    Q CP  + DF+ +    K C  +G W      N+++++Y  C+       K +Y +Y +  VG+++SI++L+ISLA+ FYF+ L+C RITLHKN+F   ++NS      +N++++ +N   V    +C+ L+    Y     YFWMLCEG+YL  +I++  F + Q +  +  +LGWG PLV   +    R      N C +    +L+Y++  PI   ++ N+ F+  I+ +L  K R+    E +   KA +A LIL P++G+  +++  +P++ +  +++ Y   +    QG L+   FCFFN E+  A+K  R+ +Q+  KA+    R ++     T  T+ ++ +
Sbjct:  154 PYNKSGLYCNRTWDGWLCWDDTPAGTFTSQYCPNYFADFDSTEKVTKYCDETGNWFRHPETNRTWSNYTLCIAHTKDKLKMAYILYYMAIVGHALSIVSLLISLAIFFYFRSLSCQRITLHKNLFCSYVLNSA--FTIVNLITVVNNPKVVQRNPVCKVLHFFHMYMLGCNYFWMLCEGIYLHTLIVVAVFAEEQHL-HWYYLLGWGFPLVPASIHAVARKKYFDDN-CWMSVETHLLYVVHGPIMAALLVNLFFLLNIVRVLVTKLRDTHRAESNMYMKAVRATLILVPLLGIQFVIIPWRPENRLAGEIYDYIMHILMHYQGLLVATIFCFFNGEVQGALK--RQWMQY--KAQWGQRRREHCSMRSTSYTATSITE 524          
BLAST of Calcitonin family peptide receptor vs. Ensembl Zebrafish
Match: calcr (calcitonin receptor [Source:ZFIN;Acc:ZDB-GENE-060503-420])

HSP 1 Score: 191.045 bits (484), Expect = 5.294e-54
Identity = 119/379 (31.40%), Postives = 205/379 (54.09%), Query Frame = 3
Query:  189 PPTDGQLYCRAIYDGLLCWNYTKAGLTVEQNCPALY-DFNVSALAYKSCLPSGEWLTKGGVNQSYTDYMACVP------KASYSIY-IYFVGYSMSIIALVISLAVLFYFKQLNCHRITLHKNMFFCNLMNSTGWLLYINVLSMHSNDSAVYS--MCQALYLIVNYTGTATYFWMLCEGLYL-LMILIFTFNKGQFIVRFCIILGWGAPLVIIILFGSLRFSVGASNLCHLDGFNNLMYIMLVPIFVTIIFNMIFMAFILGILFNKFRNHRNIEQHQGQKAAKAILILTPVMGLHSLLLLVQPDDAMWLKVHKYASALTNSLQGFLITMPFCFFNSEIHEAIKMRRRRLQFTNKARLSNSRSKNIPRVRTPQTSLALGK 1292
            P     LYC   +DG LCW+ T AG    Q CP  + DF+ +    K C  +G W      N+++++Y  C+       K +Y +Y +  VG+++SI++L+ISLA+ FYF+ L+C RITLHKN+F   ++NS      +N++++ +N   V    +C+ L+    Y     YFWMLCEG+YL  +I++  F + Q +  +  +LGWG PLV   +    R      N C +    +L+Y++  PI   ++ N+ F+  I+ +L  K R+    E +   KA +A LIL P++G+  +++  +P++ +  +++ Y   +    QG L+   FCFFN E+  A+K  R+ +Q+  KA+    R ++     T  T+ ++ +
Sbjct:  154 PYNKSGLYCNRTWDGWLCWDDTPAGTFTSQYCPNYFADFDSTEKVTKYCDETGNWFRHPETNRTWSNYTLCIAHTKDKLKMAYILYYMAIVGHALSIVSLLISLAIFFYFRSLSCQRITLHKNLFCSYVLNSA--FTIVNLITVVNNPKVVQRNPVCKVLHFFHMYMLGCNYFWMLCEGIYLHTLIVVAVFAEEQHL-HWYYLLGWGFPLVPASIHAVARKKYFDDN-CWMSVETHLLYVVHGPIMAALLVNLFFLLNIVRVLVTKLRDTHRAESNMYMKAVRATLILVPLLGIQFVIIPWRPENRLAGEIYDYIMHILMHYQGLLVATIFCFFNGEVQGALK--RQWMQY--KAQWGQRRREHCSMRSTSYTATSITE 524          
BLAST of Calcitonin family peptide receptor vs. Ensembl Zebrafish
Match: calcr (calcitonin receptor [Source:ZFIN;Acc:ZDB-GENE-060503-420])

HSP 1 Score: 191.43 bits (485), Expect = 7.551e-54
Identity = 119/379 (31.40%), Postives = 205/379 (54.09%), Query Frame = 3
Query:  189 PPTDGQLYCRAIYDGLLCWNYTKAGLTVEQNCPALY-DFNVSALAYKSCLPSGEWLTKGGVNQSYTDYMACVP------KASYSIY-IYFVGYSMSIIALVISLAVLFYFKQLNCHRITLHKNMFFCNLMNSTGWLLYINVLSMHSNDSAVYS--MCQALYLIVNYTGTATYFWMLCEGLYL-LMILIFTFNKGQFIVRFCIILGWGAPLVIIILFGSLRFSVGASNLCHLDGFNNLMYIMLVPIFVTIIFNMIFMAFILGILFNKFRNHRNIEQHQGQKAAKAILILTPVMGLHSLLLLVQPDDAMWLKVHKYASALTNSLQGFLITMPFCFFNSEIHEAIKMRRRRLQFTNKARLSNSRSKNIPRVRTPQTSLALGK 1292
            P     LYC   +DG LCW+ T AG    Q CP  + DF+ +    K C  +G W      N+++++Y  C+       K +Y +Y +  VG+++SI++L+ISLA+ FYF+ L+C RITLHKN+F   ++NS      +N++++ +N   V    +C+ L+    Y     YFWMLCEG+YL  +I++  F + Q +  +  +LGWG PLV   +    R      N C +    +L+Y++  PI   ++ N+ F+  I+ +L  K R+    E +   KA +A LIL P++G+  +++  +P++ +  +++ Y   +    QG L+   FCFFN E+  A+K  R+ +Q+  KA+    R ++     T  T+ ++ +
Sbjct:  185 PYNKSGLYCNRTWDGWLCWDDTPAGTFTSQYCPNYFADFDSTEKVTKYCDETGNWFRHPETNRTWSNYTLCIAHTKDKLKMAYILYYMAIVGHALSIVSLLISLAIFFYFRSLSCQRITLHKNLFCSYVLNSA--FTIVNLITVVNNPKVVQRNPVCKVLHFFHMYMLGCNYFWMLCEGIYLHTLIVVAVFAEEQHL-HWYYLLGWGFPLVPASIHAVARKKYFDDN-CWMSVETHLLYVVHGPIMAALLVNLFFLLNIVRVLVTKLRDTHRAESNMYMKAVRATLILVPLLGIQFVIIPWRPENRLAGEIYDYIMHILMHYQGLLVATIFCFFNGEVQGALK--RQWMQY--KAQWGQRRREHCSMRSTSYTATSITE 555          
BLAST of Calcitonin family peptide receptor vs. Ensembl Zebrafish
Match: calcr (calcitonin receptor [Source:ZFIN;Acc:ZDB-GENE-060503-420])

HSP 1 Score: 191.43 bits (485), Expect = 7.551e-54
Identity = 119/379 (31.40%), Postives = 205/379 (54.09%), Query Frame = 3
Query:  189 PPTDGQLYCRAIYDGLLCWNYTKAGLTVEQNCPALY-DFNVSALAYKSCLPSGEWLTKGGVNQSYTDYMACVP------KASYSIY-IYFVGYSMSIIALVISLAVLFYFKQLNCHRITLHKNMFFCNLMNSTGWLLYINVLSMHSNDSAVYS--MCQALYLIVNYTGTATYFWMLCEGLYL-LMILIFTFNKGQFIVRFCIILGWGAPLVIIILFGSLRFSVGASNLCHLDGFNNLMYIMLVPIFVTIIFNMIFMAFILGILFNKFRNHRNIEQHQGQKAAKAILILTPVMGLHSLLLLVQPDDAMWLKVHKYASALTNSLQGFLITMPFCFFNSEIHEAIKMRRRRLQFTNKARLSNSRSKNIPRVRTPQTSLALGK 1292
            P     LYC   +DG LCW+ T AG    Q CP  + DF+ +    K C  +G W      N+++++Y  C+       K +Y +Y +  VG+++SI++L+ISLA+ FYF+ L+C RITLHKN+F   ++NS      +N++++ +N   V    +C+ L+    Y     YFWMLCEG+YL  +I++  F + Q +  +  +LGWG PLV   +    R      N C +    +L+Y++  PI   ++ N+ F+  I+ +L  K R+    E +   KA +A LIL P++G+  +++  +P++ +  +++ Y   +    QG L+   FCFFN E+  A+K  R+ +Q+  KA+    R ++     T  T+ ++ +
Sbjct:  185 PYNKSGLYCNRTWDGWLCWDDTPAGTFTSQYCPNYFADFDSTEKVTKYCDETGNWFRHPETNRTWSNYTLCIAHTKDKLKMAYILYYMAIVGHALSIVSLLISLAIFFYFRSLSCQRITLHKNLFCSYVLNSA--FTIVNLITVVNNPKVVQRNPVCKVLHFFHMYMLGCNYFWMLCEGIYLHTLIVVAVFAEEQHL-HWYYLLGWGFPLVPASIHAVARKKYFDDN-CWMSVETHLLYVVHGPIMAALLVNLFFLLNIVRVLVTKLRDTHRAESNMYMKAVRATLILVPLLGIQFVIIPWRPENRLAGEIYDYIMHILMHYQGLLVATIFCFFNGEVQGALK--RQWMQY--KAQWGQRRREHCSMRSTSYTATSITE 555          
BLAST of Calcitonin family peptide receptor vs. Ensembl Zebrafish
Match: calcr (calcitonin receptor [Source:ZFIN;Acc:ZDB-GENE-060503-420])

HSP 1 Score: 189.889 bits (481), Expect = 2.459e-53
Identity = 119/380 (31.32%), Postives = 204/380 (53.68%), Query Frame = 3
Query:  189 PPTDGQLYCRAIYDGLLCWNYTKAGLTVEQNCPALY-DFNVSALAYKSCLPSGEWLTKGGVNQSYTDYMACVP------KASYSIY-IYFVGYSMSIIALVISLAVLFYFKQLNCHRITLHKNMFFCNLMNSTGWLLYINVLSMHSNDSAVYS---MCQALYLIVNYTGTATYFWMLCEGLYL-LMILIFTFNKGQFIVRFCIILGWGAPLVIIILFGSLRFSVGASNLCHLDGFNNLMYIMLVPIFVTIIFNMIFMAFILGILFNKFRNHRNIEQHQGQKAAKAILILTPVMGLHSLLLLVQPDDAMWLKVHKYASALTNSLQGFLITMPFCFFNSEIHEAIKMRRRRLQFTNKARLSNSRSKNIPRVRTPQTSLALGK 1292
            P     LYC   +DG LCW+ T AG    Q CP  + DF+ +    K C  +G W      N+++++Y  C+       K +Y +Y +  VG+++SI++L+ISLA+ FYF+ L+C RITLHKN+F   ++NS      +N++++ +N   V      C+ L+    Y     YFWMLCEG+YL  +I++  F + Q +  +  +LGWG PLV   +    R      N C +    +L+Y++  PI   ++ N+ F+  I+ +L  K R+    E +   KA +A LIL P++G+  +++  +P++ +  +++ Y   +    QG L+   FCFFN E+  A+K  R+ +Q+  KA+    R ++     T  T+ ++ +
Sbjct:  192 PYNKSGLYCNRTWDGWLCWDDTPAGTFTSQYCPNYFADFDSTEKVTKYCDETGNWFRHPETNRTWSNYTLCIAHTKDKLKMAYILYYMAIVGHALSIVSLLISLAIFFYFRSLSCQRITLHKNLFCSYVLNSA--FTIVNLITVVNNPKVVQRNPISCKVLHFFHMYMLGCNYFWMLCEGIYLHTLIVVAVFAEEQHL-HWYYLLGWGFPLVPASIHAVARKKYFDDN-CWMSVETHLLYVVHGPIMAALLVNLFFLLNIVRVLVTKLRDTHRAESNMYMKAVRATLILVPLLGIQFVIIPWRPENRLAGEIYDYIMHILMHYQGLLVATIFCFFNGEVQGALK--RQWMQY--KAQWGQRRREHCSMRSTSYTATSITE 563          

HSP 2 Score: 52.7582 bits (125), Expect = 7.875e-7
Identity = 21/58 (36.21%), Postives = 31/58 (53.45%), Query Frame = 3
Query:  210 YCRAIYDGLLCWNYTKAGLTVEQNCPALYDFNVSALAYKSCLPSGEWLTKGGVNQSYT 383
            +C   +DGLLCW+ T AG    QNCP    F+      K C  SG W+    +N++++
Sbjct:   72 FCSRFWDGLLCWDETPAGTFASQNCPDYPSFDPLEKVTKYCDESGNWVHSASINKTWS 129          
BLAST of Calcitonin family peptide receptor vs. Ensembl Xenopus
Match: calcrl (calcitonin receptor like receptor [Source:NCBI gene;Acc:549647])

HSP 1 Score: 179.874 bits (455), Expect = 2.000e-50
Identity = 118/387 (30.49%), Postives = 192/387 (49.61%), Query Frame = 3
Query:  177 MPPPPPTDGQLYCRAIYDGLLCWNYTKAGLTVEQNCPALY-DFNVSALAYKSCLPSGEWLTKGGVNQSYTDYMAC-------VPKASYSIYIYFVGYSMSIIALVISLAVLFYFKQLNCHRITLHKNMFFCNLMNSTGWLLYINVLSMHSNDSAVYSM----CQALYLIVNYTGTATYFWMLCEGLYL-LMILIFTFNKGQFIVRFCIILGWGAPLVIIILFGSLRFSVGASNLCHLDGFNNLMYIMLVPIFVTIIFNMIFMAFILGILFNKFRNHRNIEQHQGQKAAKAILILTPVMGLHSLLLLVQPDDAMWLKVHKYASALTNSLQGFLITMPFCFFNSEIHEAIKMRRRRLQFTNKARLSNSRSKNIPRVRTPQTSLALGKSY 1298
            M  P       +C   +DG LCW    AG+  EQ CP  + DF+ S    K C  +G W      N+++T+Y  C       V  A    Y+  +G+ +SI +L+ISL + FYFK L+C RITLHKN+FF  + NS   ++ I  LS  +N+ A+ +     C+    I  Y     YFWMLCEG+YL  +I++  F + Q ++ +  +LGWG PL+   +    R S+  ++ C +    +L+YI+  PI   ++ N+ F+  I+ +L  K +     E +   KA +A LIL P++G+  +L   +P+  +  +++ Y   +    QG L+   FCFFN E+   +K    + +    +  ++S             S   G +Y
Sbjct:   63 MQEPANGKEGHFCNRTWDGWLCWGDVSAGVISEQRCPDYFQDFDPSEKVTKECGKNGHWFRHPDSNRTWTNYTRCNTFTHEKVKTALNLYYLTIIGHGLSIASLLISLGIFFYFKNLSCQRITLHKNLFFSFVCNS---IITIISLSAVANNQALVATNPVSCKISQFIHLYLMGCNYFWMLCEGIYLHTLIVVAVFAEKQHLMWY-YLLGWGFPLIPACIHAVAR-SLYYNDNCWISSETHLLYIIHGPICAALLVNLFFLLNIVRVLITKLKVTHQAESNLYMKAVRATLILVPLLGIEFVLFPWKPEGRIAEEIYDYVMHILMHYQGLLVATIFCFFNGEVQAVLKRHWNQYKIQFGSSFAHSEGLRSASYTVSSISEIQGTTY 444          
BLAST of Calcitonin family peptide receptor vs. Ensembl Xenopus
Match: calcrl (calcitonin receptor like receptor [Source:NCBI gene;Acc:549647])

HSP 1 Score: 159.844 bits (403), Expect = 2.490e-43
Identity = 104/320 (32.50%), Postives = 168/320 (52.50%), Query Frame = 3
Query:  177 MPPPPPTDGQLYCRAIYDGLLCWNYTKAGLTVEQNCPALY-DFNVSALAYKSCLPSGEWLTKGGVNQSYTDYMAC-------VPKASYSIYIYFVGYSMSIIALVISLAVLFYFKQLNCHRITLHKNMFFCNLMNSTGWLLYINVLSMHSNDSAVYSM----CQALYLIVNYTGTATYFWMLCEGLYL-LMILIFTFNKGQFIVRFCIILGWGAPLVIIILFGSLRFSVGASNLCHLDGFNNLMYIMLVPIFVTIIFNMIFMAFILGILFNKFRNHRNIEQHQGQKAAKAILILTPVMGLHSLLLLVQPDDAMWLKVHKY 1097
            M  P       +C   +DG LCW    AG+  EQ CP  + DF+ S    K C  +G W      N+++T+Y  C       V  A    Y+  +G+ +SI +L+ISL + FYFK L+C RITLHKN+FF  + NS   ++ I  LS  +N+ A+ +     C+    I  Y     YFWMLCEG+YL  +I++  F + Q ++ +  +LGWG PL+   +    R S+  ++ C +    +L+YI+  PI   ++ N+ F+  I+ +L  K +     E +   KA +A LIL P++G+  +L   +P+  +  +++ Y
Sbjct:   33 MQEPANGKEGHFCNRTWDGWLCWGDVSAGVISEQRCPDYFQDFDPSEKVTKECGKNGHWFRHPDSNRTWTNYTRCNTFTHEKVKTALNLYYLTIIGHGLSIASLLISLGIFFYFKNLSCQRITLHKNLFFSFVCNS---IITIISLSAVANNQALVATNPVSCKISQFIHLYLMGCNYFWMLCEGIYLHTLIVVAVFAEKQHLMWY-YLLGWGFPLIPACIHAVAR-SLYYNDNCWISSETHLLYIIHGPICAALLVNLFFLLNIVRVLITKLKVTHQAESNLYMKAVRATLILVPLLGIEFVLFPWKPEGRIAEEIYDY 347          
BLAST of Calcitonin family peptide receptor vs. Ensembl Xenopus
Match: calcrl (calcitonin receptor like receptor [Source:NCBI gene;Acc:549647])

HSP 1 Score: 159.458 bits (402), Expect = 4.278e-43
Identity = 104/320 (32.50%), Postives = 168/320 (52.50%), Query Frame = 3
Query:  177 MPPPPPTDGQLYCRAIYDGLLCWNYTKAGLTVEQNCPALY-DFNVSALAYKSCLPSGEWLTKGGVNQSYTDYMAC-------VPKASYSIYIYFVGYSMSIIALVISLAVLFYFKQLNCHRITLHKNMFFCNLMNSTGWLLYINVLSMHSNDSAVYSM----CQALYLIVNYTGTATYFWMLCEGLYL-LMILIFTFNKGQFIVRFCIILGWGAPLVIIILFGSLRFSVGASNLCHLDGFNNLMYIMLVPIFVTIIFNMIFMAFILGILFNKFRNHRNIEQHQGQKAAKAILILTPVMGLHSLLLLVQPDDAMWLKVHKY 1097
            M  P       +C   +DG LCW    AG+  EQ CP  + DF+ S    K C  +G W      N+++T+Y  C       V  A    Y+  +G+ +SI +L+ISL + FYFK L+C RITLHKN+FF  + NS   ++ I  LS  +N+ A+ +     C+    I  Y     YFWMLCEG+YL  +I++  F + Q ++ +  +LGWG PL+   +    R S+  ++ C +    +L+YI+  PI   ++ N+ F+  I+ +L  K +     E +   KA +A LIL P++G+  +L   +P+  +  +++ Y
Sbjct:   45 MQEPANGKEGHFCNRTWDGWLCWGDVSAGVISEQRCPDYFQDFDPSEKVTKECGKNGHWFRHPDSNRTWTNYTRCNTFTHEKVKTALNLYYLTIIGHGLSIASLLISLGIFFYFKNLSCQRITLHKNLFFSFVCNS---IITIISLSAVANNQALVATNPVSCKISQFIHLYLMGCNYFWMLCEGIYLHTLIVVAVFAEKQHLMWY-YLLGWGFPLIPACIHAVAR-SLYYNDNCWISSETHLLYIIHGPICAALLVNLFFLLNIVRVLITKLKVTHQAESNLYMKAVRATLILVPLLGIEFVLFPWKPEGRIAEEIYDY 359          
BLAST of Calcitonin family peptide receptor vs. Ensembl Xenopus
Match: calcrl (calcitonin receptor like receptor [Source:NCBI gene;Acc:549647])

HSP 1 Score: 153.295 bits (386), Expect = 3.257e-41
Identity = 106/326 (32.52%), Postives = 172/326 (52.76%), Query Frame = 3
Query:  207 LYCRAIYDGLLCWNYTKAGLTVEQNCPALY-DFNVSALAYKSCLPSGEWLTKGGVNQSYTDYMAC-------VPKASYSIYIYFVGYSMSIIALVISLAVLFYFKQLNCHRITLHKNMFFCNLMNSTGWLLYINVLSMHSNDSAVYSM----CQALYLIVNYTGTATYFWMLCEGLYL-LMILIFTFNKGQFIVRFCIILGWGAPLVIIILFGSLRFSVGASNLCHLDGFNNLMYIMLVPIFVTIIFNMIFMAFILGILFNKFRNHRNIEQHQGQKAAKAILILTPVMGLHSLLLLVQPDDAMWLKVHKYASALTNSLQ-GFLITM 1142
            L  +  +DG LCW    AG+  EQ CP  + DF+ S    K C  +G W      N+++T+Y  C       V  A    Y+  +G+ +SI +L+ISL + FYFK L+C RITLHKN+FF  + NS   ++ I  LS  +N+ A+ +     C+    I  Y     YFWMLCEG+YL  +I++  F + Q ++ +  +LGWG PL+   +    R S+  ++ C +    +L+YI+  PI   ++ N+ F+  I+ +L  K +     E +   KA +A LIL P++G+  +L   +P+  +  +++ Y   +    Q  FLI +
Sbjct:   45 LVTKLTWDGWLCWGDVSAGVISEQRCPDYFQDFDPSEKVTKECGKNGHWFRHPDSNRTWTNYTRCNTFTHEKVKTALNLYYLTIIGHGLSIASLLISLGIFFYFKNLSCQRITLHKNLFFSFVCNS---IITIISLSAVANNQALVATNPVSCKISQFIHLYLMGCNYFWMLCEGIYLHTLIVVAVFAEKQHLMWY-YLLGWGFPLIPACIHAVAR-SLYYNDNCWISSETHLLYIIHGPICAALLVNLFFLLNIVRVLITKLKVTHQAESNLYMKAVRATLILVPLLGIEFVLFPWKPEGRIAEEIYDYVMHILMHYQVNFLINL 365          
BLAST of Calcitonin family peptide receptor vs. Ensembl Xenopus
Match: yif1b (Yip1 interacting factor homolog B, membrane trafficking protein [Source:Xenbase;Acc:XB-GENE-922881])

HSP 1 Score: 149.443 bits (376), Expect = 7.833e-40
Identity = 103/367 (28.07%), Postives = 174/367 (47.41%), Query Frame = 3
Query:  195 TDGQLYCRAIYDGL-LCWNYTKAGLTVEQNCPALYD---FNVSALAYKSCLPSGEWLTKGGVNQSYTDYMACVPKASY--SIYIYFVGYSMSIIALVISLAVLFYFKQLNCHRITLHKNMFFCNLMNSTGWLLYINVLSMHSNDSAVYSMCQALYLIVNYTGTATYFWMLCEGLYLLMILIFTFNKGQFIVRFCIILGWGAPLVIIILF--GSLRFS-----VGASNLCHLDGFNNLMYIMLVPIFVTIIFNMIFMAFILGILFNKFRNHRNIEQHQGQKAAKAILILTPVMGLHSLLLLVQP-DDAMWLKVHKYASALTNSLQGFLITMPFCFFNSEIHEAIKMRRRRLQFTNKARLSNSRSKNIP 1253
            ++  L C A  D +  CW  T AG  V + CP  +    +N +   Y+ C  +G W  +G   Q          K  Y  +I I F+G+S+S+ AL+++  +    + + C R  +H N+    ++ +  W +    LS  ++DS V   C+ + +  NY     +FWM  EG YL   ++ T++  +      I +GW  P  II+ +  G L +       G     + D      +I   P+ + ++ N IF+  I+ IL  K R     E  Q +KA KA L+L P++G+  +L  V P +D +   V  Y ++   S QGF +++ +CF NSE+  A++ R  R Q  +  R   +R+ +IP
Sbjct:   11 SNNCLACNASIDMIGTCWPRTAAGQMVARPCPEYFQGVQYNTTGNVYRECHLNGSWAGRGDYTQCQEILKQEKTKVHYHIAIVINFLGHSISLCALLVAFILFLRLRSIRCLRNIIHWNLITAFILRNVTWFVMQLTLSHEAHDSNVV-WCRLVTIAHNYFYVTNFFWMFGEGCYLHTAIVLTYSTDKLRKWMFICIGWCIPFPIIVAWAIGKLYYDNEKCWFGKKAGVYTD------FIYQGPVILVLLINFIFLFNIVRILMTKLRASTTSETIQYRKAVKATLVLLPLLGITYMLFFVTPGEDEISRVVFIYFNSFLQSFQGFFVSVFYCFLNSEVRSAVRKRWHRWQDKHSIRARVARAMSIP 370          
BLAST of Calcitonin family peptide receptor vs. Ensembl Mouse
Match: Calcr (calcitonin receptor [Source:MGI Symbol;Acc:MGI:101950])

HSP 1 Score: 190.66 bits (483), Expect = 2.185e-54
Identity = 113/375 (30.13%), Postives = 196/375 (52.27%), Query Frame = 3
Query:  189 PPTDGQ-LYCRAIYDGLLCWNYTKAGLTVEQNCPALY-DFNVSALAYKSCLPSGEWLTKGGVNQSYTDYMACVPKASYSI-------YIYFVGYSMSIIALVISLAVLFYFKQLNCHRITLHKNMFFCNLMNSTGWLLYINVLSMHSNDSAVYS---MCQALYLIVNYTGTATYFWMLCEGLYLLMILIFTFNKGQFIVRFCIILGWGAPLVIIILFGSLRFSVGASNLCHLDGFNNLMYIMLVPIFVTIIFNMIFMAFILGILFNKFRNHRNIEQHQGQKAAKAILILTPVMGLHSLLLLVQPDDAMWLKVHKYASALTNSLQGFLITMPFCFFNSEIHEAIKMRRRRLQFT-------NKARLSNSRSKNIPR 1256
            P  +G+ LYC   +DG +CW+ T AG T  Q+CP  + DF+ +    K C  +GEW      N+++++Y  C    S  +       Y+  VG+S+SI ALV S+ + + FK L+C R+TLHK+MF   ++NS   ++ I+++ +  N   V      C+ L+ +  Y  +  YFWMLCEG+YL  +++      +  +R+  +LGWG P+V  I+    R ++  ++ C L    +L+YI+  P+ V ++ N  F+  I+ +L  K R     E +   KA KA ++L P++G+  ++   +P + +  K++ Y        QGF +   +CF N E+   + ++R+  QF         + R   +R  + PR
Sbjct:   80 PSYEGEGLYCNRTWDGWMCWDDTPAGATAYQHCPDYFPDFDTAEKVSKYCDENGEWFRHPDSNRTWSNYTLCNAFTSEKLQNAYVLYYLALVGHSLSIAALVASMLIFWIFKNLSCQRVTLHKHMFLTYILNSI--IIIIHLVEVVPNGDLVRRDPISCKVLHFLHQYMMSCNYFWMLCEGIYLHTLIVMAVFTDEQRLRWYYLLGWGFPIVPTIIHAITR-ALYYNDNCWLSAETHLLYIIHGPVMVALVVNFFFLLNIVRVLVTKMRQTHEAESYMYLKAVKATMVLVPLLGIQFVVFPWRPSNKVLGKIYDYLMHSLIHFQGFFVATIYCFCNHEVQ--VTLKRQWTQFKIQWSQRWGRRRRPTNRVVSAPR 449          
BLAST of Calcitonin family peptide receptor vs. Ensembl Mouse
Match: Calcr (calcitonin receptor [Source:MGI Symbol;Acc:MGI:101950])

HSP 1 Score: 190.66 bits (483), Expect = 2.185e-54
Identity = 113/375 (30.13%), Postives = 196/375 (52.27%), Query Frame = 3
Query:  189 PPTDGQ-LYCRAIYDGLLCWNYTKAGLTVEQNCPALY-DFNVSALAYKSCLPSGEWLTKGGVNQSYTDYMACVPKASYSI-------YIYFVGYSMSIIALVISLAVLFYFKQLNCHRITLHKNMFFCNLMNSTGWLLYINVLSMHSNDSAVYS---MCQALYLIVNYTGTATYFWMLCEGLYLLMILIFTFNKGQFIVRFCIILGWGAPLVIIILFGSLRFSVGASNLCHLDGFNNLMYIMLVPIFVTIIFNMIFMAFILGILFNKFRNHRNIEQHQGQKAAKAILILTPVMGLHSLLLLVQPDDAMWLKVHKYASALTNSLQGFLITMPFCFFNSEIHEAIKMRRRRLQFT-------NKARLSNSRSKNIPR 1256
            P  +G+ LYC   +DG +CW+ T AG T  Q+CP  + DF+ +    K C  +GEW      N+++++Y  C    S  +       Y+  VG+S+SI ALV S+ + + FK L+C R+TLHK+MF   ++NS   ++ I+++ +  N   V      C+ L+ +  Y  +  YFWMLCEG+YL  +++      +  +R+  +LGWG P+V  I+    R ++  ++ C L    +L+YI+  P+ V ++ N  F+  I+ +L  K R     E +   KA KA ++L P++G+  ++   +P + +  K++ Y        QGF +   +CF N E+   + ++R+  QF         + R   +R  + PR
Sbjct:   80 PSYEGEGLYCNRTWDGWMCWDDTPAGATAYQHCPDYFPDFDTAEKVSKYCDENGEWFRHPDSNRTWSNYTLCNAFTSEKLQNAYVLYYLALVGHSLSIAALVASMLIFWIFKNLSCQRVTLHKHMFLTYILNSI--IIIIHLVEVVPNGDLVRRDPISCKVLHFLHQYMMSCNYFWMLCEGIYLHTLIVMAVFTDEQRLRWYYLLGWGFPIVPTIIHAITR-ALYYNDNCWLSAETHLLYIIHGPVMVALVVNFFFLLNIVRVLVTKMRQTHEAESYMYLKAVKATMVLVPLLGIQFVVFPWRPSNKVLGKIYDYLMHSLIHFQGFFVATIYCFCNHEVQ--VTLKRQWTQFKIQWSQRWGRRRRPTNRVVSAPR 449          
BLAST of Calcitonin family peptide receptor vs. Ensembl Mouse
Match: Calcr (calcitonin receptor [Source:MGI Symbol;Acc:MGI:101950])

HSP 1 Score: 190.66 bits (483), Expect = 2.185e-54
Identity = 113/375 (30.13%), Postives = 196/375 (52.27%), Query Frame = 3
Query:  189 PPTDGQ-LYCRAIYDGLLCWNYTKAGLTVEQNCPALY-DFNVSALAYKSCLPSGEWLTKGGVNQSYTDYMACVPKASYSI-------YIYFVGYSMSIIALVISLAVLFYFKQLNCHRITLHKNMFFCNLMNSTGWLLYINVLSMHSNDSAVYS---MCQALYLIVNYTGTATYFWMLCEGLYLLMILIFTFNKGQFIVRFCIILGWGAPLVIIILFGSLRFSVGASNLCHLDGFNNLMYIMLVPIFVTIIFNMIFMAFILGILFNKFRNHRNIEQHQGQKAAKAILILTPVMGLHSLLLLVQPDDAMWLKVHKYASALTNSLQGFLITMPFCFFNSEIHEAIKMRRRRLQFT-------NKARLSNSRSKNIPR 1256
            P  +G+ LYC   +DG +CW+ T AG T  Q+CP  + DF+ +    K C  +GEW      N+++++Y  C    S  +       Y+  VG+S+SI ALV S+ + + FK L+C R+TLHK+MF   ++NS   ++ I+++ +  N   V      C+ L+ +  Y  +  YFWMLCEG+YL  +++      +  +R+  +LGWG P+V  I+    R ++  ++ C L    +L+YI+  P+ V ++ N  F+  I+ +L  K R     E +   KA KA ++L P++G+  ++   +P + +  K++ Y        QGF +   +CF N E+   + ++R+  QF         + R   +R  + PR
Sbjct:   80 PSYEGEGLYCNRTWDGWMCWDDTPAGATAYQHCPDYFPDFDTAEKVSKYCDENGEWFRHPDSNRTWSNYTLCNAFTSEKLQNAYVLYYLALVGHSLSIAALVASMLIFWIFKNLSCQRVTLHKHMFLTYILNSI--IIIIHLVEVVPNGDLVRRDPISCKVLHFLHQYMMSCNYFWMLCEGIYLHTLIVMAVFTDEQRLRWYYLLGWGFPIVPTIIHAITR-ALYYNDNCWLSAETHLLYIIHGPVMVALVVNFFFLLNIVRVLVTKMRQTHEAESYMYLKAVKATMVLVPLLGIQFVVFPWRPSNKVLGKIYDYLMHSLIHFQGFFVATIYCFCNHEVQ--VTLKRQWTQFKIQWSQRWGRRRRPTNRVVSAPR 449          
BLAST of Calcitonin family peptide receptor vs. Ensembl Mouse
Match: Calcr (calcitonin receptor [Source:MGI Symbol;Acc:MGI:101950])

HSP 1 Score: 183.726 bits (465), Expect = 1.780e-51
Identity = 113/411 (27.49%), Postives = 200/411 (48.66%), Query Frame = 3
Query:  189 PPTDGQ-LYCRAIYDGLLCWNYTKAGLTVEQNCPALY-DFNVSALAYKSCLPSGEWLTKGGVNQSYTDYMACVPKASYSI-------YIYFVGYSMSIIALVISLAVLFYFKQLNCHRITLHKNMFFCNLMNS------------TGWLLYINVLSMHSNDSAVYSM--------------------------CQALYLIVNYTGTATYFWMLCEGLYLLMILIFTFNKGQFIVRFCIILGWGAPLVIIILFGSLRFSVGASNLCHLDGFNNLMYIMLVPIFVTIIFNMIFMAFILGILFNKFRNHRNIEQHQGQKAAKAILILTPVMGLHSLLLLVQPDDAMWLKVHKYASALTNSLQGFLITMPFCFFNSEIHEAIKMRRRRLQFT-------NKARLSNSRSKNIPRV 1259
            P  +G+ LYC   +DG +CW+ T AG T  Q+CP  + DF+ +    K C  +GEW      N+++++Y  C    S  +       Y+  VG+S+SI ALV S+ + + FK L+C R+TLHK+MF   ++NS             G L+  + + +  +++ +++M                          C+ L+ +  Y  +  YFWMLCEG+YL  +++      +  +R+  +LGWG P+V  I+    R ++  ++ C L    +L+YI+  P+ V ++ N  F+  I+ +L  K R     E +   KA KA ++L P++G+  ++   +P + +  K++ Y        QGF +   +CF N E+   + ++R+  QF         + R   +R  + PR 
Sbjct:   80 PSYEGEGLYCNRTWDGWMCWDDTPAGATAYQHCPDYFPDFDTAEKVSKYCDENGEWFRHPDSNRTWSNYTLCNAFTSEKLQNAYVLYYLALVGHSLSIAALVASMLIFWIFKNLSCQRVTLHKHMFLTYILNSIIIIIHLVEVVPNGDLVRRDPMHIFHHNTHMWTMQWELSPPLPLSAHEGKMDPHASEVISCKVLHFLHQYMMSCNYFWMLCEGIYLHTLIVMAVFTDEQRLRWYYLLGWGFPIVPTIIHAITR-ALYYNDNCWLSAETHLLYIIHGPVMVALVVNFFFLLNIVRVLVTKMRQTHEAESYMYLKAVKATMVLVPLLGIQFVVFPWRPSNKVLGKIYDYLMHSLIHFQGFFVATIYCFCNHEVQ--VTLKRQWTQFKIQWSQRWGRRRRPTNRVVSAPRA 487          
BLAST of Calcitonin family peptide receptor vs. Ensembl Mouse
Match: Calcr (calcitonin receptor [Source:MGI Symbol;Acc:MGI:101950])

HSP 1 Score: 183.726 bits (465), Expect = 1.780e-51
Identity = 113/411 (27.49%), Postives = 200/411 (48.66%), Query Frame = 3
Query:  189 PPTDGQ-LYCRAIYDGLLCWNYTKAGLTVEQNCPALY-DFNVSALAYKSCLPSGEWLTKGGVNQSYTDYMACVPKASYSI-------YIYFVGYSMSIIALVISLAVLFYFKQLNCHRITLHKNMFFCNLMNS------------TGWLLYINVLSMHSNDSAVYSM--------------------------CQALYLIVNYTGTATYFWMLCEGLYLLMILIFTFNKGQFIVRFCIILGWGAPLVIIILFGSLRFSVGASNLCHLDGFNNLMYIMLVPIFVTIIFNMIFMAFILGILFNKFRNHRNIEQHQGQKAAKAILILTPVMGLHSLLLLVQPDDAMWLKVHKYASALTNSLQGFLITMPFCFFNSEIHEAIKMRRRRLQFT-------NKARLSNSRSKNIPRV 1259
            P  +G+ LYC   +DG +CW+ T AG T  Q+CP  + DF+ +    K C  +GEW      N+++++Y  C    S  +       Y+  VG+S+SI ALV S+ + + FK L+C R+TLHK+MF   ++NS             G L+  + + +  +++ +++M                          C+ L+ +  Y  +  YFWMLCEG+YL  +++      +  +R+  +LGWG P+V  I+    R ++  ++ C L    +L+YI+  P+ V ++ N  F+  I+ +L  K R     E +   KA KA ++L P++G+  ++   +P + +  K++ Y        QGF +   +CF N E+   + ++R+  QF         + R   +R  + PR 
Sbjct:   80 PSYEGEGLYCNRTWDGWMCWDDTPAGATAYQHCPDYFPDFDTAEKVSKYCDENGEWFRHPDSNRTWSNYTLCNAFTSEKLQNAYVLYYLALVGHSLSIAALVASMLIFWIFKNLSCQRVTLHKHMFLTYILNSIIIIIHLVEVVPNGDLVRRDPMHIFHHNTHMWTMQWELSPPLPLSAHEGKMDPHASEVISCKVLHFLHQYMMSCNYFWMLCEGIYLHTLIVMAVFTDEQRLRWYYLLGWGFPIVPTIIHAITR-ALYYNDNCWLSAETHLLYIIHGPVMVALVVNFFFLLNIVRVLVTKMRQTHEAESYMYLKAVKATMVLVPLLGIQFVVFPWRPSNKVLGKIYDYLMHSLIHFQGFFVATIYCFCNHEVQ--VTLKRQWTQFKIQWSQRWGRRRRPTNRVVSAPRA 487          
BLAST of Calcitonin family peptide receptor vs. UniProt/SwissProt
Match: sp|O08893|CALCR_CAVPO (Calcitonin receptor OS=Cavia porcellus OX=10141 GN=CALCR PE=2 SV=1)

HSP 1 Score: 194.897 bits (494), Expect = 3.487e-55
Identity = 121/402 (30.10%), Postives = 207/402 (51.49%), Query Frame = 3
Query:   93 RTRSPSFMSFQNDSFDY------LELERTSCEAQMPPPPPTDGQ-LYCRAIYDGLLCWNYTKAGLTVEQNCPALY-DFNVSALAYKSCLPSGEWLTKGGVNQSYTDYMAC---VPKASYSIYIYF----VGYSMSIIALVISLAVLFYFKQLNCHRITLHKNMFFCNLMNSTGWLLYINVLSMHSNDSAVYS---MCQALYLIVNYTGTATYFWMLCEGLYL-LMILIFTFNKGQFIVRFCIILGWGAPLVIIILFGSLRFSVGASNLCHLDGFNNLMYIMLVPIFVTIIFNMIFMAFILGILFNKFRNHRNIEQHQGQKAAKAILILTPVMGLHSLLLLVQPDDAMWLKVHKYASALTNSLQGFLITMPFCFFNSEIHEAIKMRRRRLQFTNKARLSNSRS 1241
            R+ + +F +F+ + + Y      L   +  C  +M   PP +G+  YC   +DG +CW+ T AG+   Q CP  + DF+ +    K C  SG W      N+++++Y  C    P+   + Y+ +    VG+SMSII LV+SL +  YF+ L C R+TLHKNMF   ++NS   ++ I+++ +  N   V      C+ L+    Y     YFWMLCEG+YL  +I++  FN+ + + R+  +LGWG PLV   +    R ++  ++ C +    +L+YI+  P+ V ++ N  F+  I+ +L  K R     E +   KA KA +IL P++G+  ++   +P + +  K++ Y        QGF +   +CF N+E+   +K +  + +     R     S
Sbjct:   25 RSENLTFPTFEPEPYLYSVGRKKLVDAQYRCYDRMQQLPPYEGEGPYCNRTWDGWMCWDDTPAGVLSVQLCPDYFPDFDPTEKVTKYCDESGVWFKHPENNRTWSNYTLCNAFTPEKLQNAYVLYYLAIVGHSMSIITLVVSLGIFVYFRSLGCQRVTLHKNMFLTYILNSM--IIIIHLVEVVPNGELVRKDPVSCKILHFFHQYMMACNYFWMLCEGIYLHTLIVVSVFNEAKHL-RWYYLLGWGFPLVPTTIHAITR-ALYFNDNCWISVDTHLLYIIHGPVMVALVVNFFFLLNIVRVLVTKMRETHEAESYMYLKAVKATMILVPLLGIQFVVFPWRPSNKVLGKIYDYFMHSLIHFQGFFVATIYCFCNNEVQTTLKRQWAQFKIQWNQRWGTRPS 422          
BLAST of Calcitonin family peptide receptor vs. UniProt/SwissProt
Match: sp|P79222|CALCR_RABIT (Calcitonin receptor OS=Oryctolagus cuniculus OX=9986 GN=CALCR PE=2 SV=1)

HSP 1 Score: 191.815 bits (486), Expect = 4.627e-54
Identity = 117/362 (32.32%), Postives = 191/362 (52.76%), Query Frame = 3
Query:  162 SCEAQMPPPPPTDGQ-LYCRAIYDGLLCWNYTKAGLTVEQNCPALY-DFNVSALAYKSCLPSGEWLTKGGVNQSYTDYMAC---VPKASYSIYIYF----VGYSMSIIALVISLAVLFYFKQLNCHRITLHKNMFFCNLMNSTGWLLYINVLSMHSNDSAVYS---MCQALYLIVNYTGTATYFWMLCEGLYL-LMILIFTFNKGQFIVRFCIILGWGAPLVIIILFGSLRFSVGASNLCHLDGFNNLMYIMLVPIFVTIIFNMIFMAFILGILFNKFRNHRNIEQHQGQKAAKAILILTPVMGLHSLLLLVQPDDAMWLKVHKYASALTNSLQGFLITMPFCFFNSEIHEAIKMRRRRLQF 1208
             C  +M   PP  G+  YC   +DG +CW+ T AG+   Q CP  + DF+ +    K C  +G W    G NQ++++Y  C    P+   + Y+ +    VG+S+SI  LVISL +   F+ L C R+TLHKNMF   ++NS   ++ I+++ +  N   V      C+ L+    Y  +  YFWMLCEG+YL  +I++  F K Q + R+  +LGWG PLV   +    R ++  ++ C +    +L+YI+  P+   ++ N  F+  I+ +L  K R     E H   KA KA +IL P++G+  ++   +P + +  K++ Y        QGF +   +CF N+E+   +K  R+ +QF
Sbjct:   54 KCYDRMEQLPPYQGEGPYCNRTWDGWMCWDDTPAGVLGFQYCPDYFPDFDPTEKVTKYCDETGVWFKHPGNNQTWSNYTMCNAFTPEKLQNAYVLYYLAIVGHSLSIFTLVISLGIFKCFRSLGCQRVTLHKNMFLTYILNSM--IIIIHLVEVVPNGELVRRDPVSCKVLHFFHQYMMSCNYFWMLCEGIYLHTLIVVAVFAKQQHL-RWYYLLGWGFPLVPTTIHAITR-AIYFNDNCWMSVETHLLYIIHGPVMAALVVNFFFLLNIVRVLVTKMRETLEAESHMYLKAVKATMILVPLLGIQFVVFPWRPSNKILGKIYDYLMHSLIHFQGFFVATIYCFCNNEVQTTVK--RQWVQF 409          
BLAST of Calcitonin family peptide receptor vs. UniProt/SwissProt
Match: sp|P30988|CALCR_HUMAN (Calcitonin receptor OS=Homo sapiens OX=9606 GN=CALCR PE=1 SV=3)

HSP 1 Score: 190.66 bits (483), Expect = 1.008e-53
Identity = 119/376 (31.65%), Postives = 195/376 (51.86%), Query Frame = 3
Query:  162 SCEAQMPPPPPTDGQ-LYCRAIYDGLLCWNYTKAGLTVEQNCPALY-DFNVSALAYKSCLPSGEWLTKGGVNQSYTDYMAC---VPKASYSIYIYF----VGYSMSIIALVISLAVLFYFKQLNCHRITLHKNMFFCNLMNSTGWLLYINVLSMHSNDSAVYS---MCQALYLIVNYTGTATYFWMLCEGLYL-LMILIFTFNKGQFIVRFCIILGWGAPLVIIILFGSLRFSVGASNLCHLDGFNNLMYIMLVPIFVTIIFNMIFMAFILGILFNKFRNHRNIEQHQGQKAAKAILILTPVMGLHSLLLLVQPDDAMWLKVHKYASALTNSLQGFLITMPFCFFNSEIHEAIKMR--RRRLQFTNK-ARLSNSRS 1241
             C  +M   P   G+  YC   +DG LCW+ T AG+   Q CP  + DF+ S    K C   G W      N+++++Y  C    P+   + Y+ +    VG+S+SI  LVISL +  +F+ L C R+TLHKNMF   ++NS   ++ I+++ +  N   V      C+ L+    Y     YFWMLCEG+YL  +I++  F + Q + R+  +LGWG PLV   +    R +V  ++ C L    +L+YI+  P+   ++ N  F+  I+ +L  K R     E H   KA KA +IL P++G+  ++   +P + M  K++ Y        QGF +   +CF N+E+   +K +  + ++Q+  +  R  ++RS
Sbjct:   54 KCYDRMQQLPAYQGEGPYCNRTWDGWLCWDDTPAGVLSYQFCPDYFPDFDPSEKVTKYCDEKGVWFKHPENNRTWSNYTMCNAFTPEKLKNAYVLYYLAIVGHSLSIFTLVISLGIFVFFRSLGCQRVTLHKNMFLTYILNSM--IIIIHLVEVVPNGELVRRDPVSCKILHFFHQYMMACNYFWMLCEGIYLHTLIVVAVFTEKQRL-RWYYLLGWGFPLVPTTIHAITR-AVYFNDNCWLSVETHLLYIIHGPVMAALVVNFFFLLNIVRVLVTKMRETHEAESHMYLKAVKATMILVPLLGIQFVVFPWRPSNKMLGKIYDYVMHSLIHFQGFFVATIYCFCNNEVQTTVKRQWAQFKIQWNQRWGRRPSNRS 425          
BLAST of Calcitonin family peptide receptor vs. UniProt/SwissProt
Match: sp|Q7ZXS8|CALRL_XENLA (Calcitonin gene-related peptide type 1 receptor OS=Xenopus laevis OX=8355 GN=calcrl PE=2 SV=1)

HSP 1 Score: 185.652 bits (470), Expect = 8.600e-52
Identity = 121/371 (32.61%), Postives = 195/371 (52.56%), Query Frame = 3
Query:  180 PPPPPTDGQLYCRAIYDGLLCWNYTKAGLTVEQNCPALY-DFNVSALAYKSCLPSGEWLTKGGVNQSYTDYMAC-------VPKASYSIYIYFVGYSMSIIALVISLAVLFYFKQLNCHRITLHKNMFFCNLMNSTGWLLYINVLSMHSNDSAVYS----MCQALYLIVNYTGTATYFWMLCEGLYL-LMILIFTFNKGQFIVRFCIILGWGAPLVIIILFGSLRFSVGASNLCHLDGFNNLMYIMLVPIFVTIIFNMIFMAFILGILFNKFRNHRNIEQHQGQKAAKAILILTPVMGLHSLLLLVQPDDAMWLKVHKYASALTNSLQGFLITMPFCFFNSEIHEAIKMR--RRRLQFTNKARLSNSRSKN 1247
             P    +GQ +C   +DG LCW    AG+  EQ CP  + DF+ S    K C  +G W      N+++T+Y  C       V  A    Y+  +G+ +SI +L+ISL + FYFK L+C RITLHKN+FF  + NS   ++ I  LS  +N+ A+ +    +C+    I  Y     YFWMLCEG+YL  +I++  F + Q ++ +  +LGWG PL+   +    R S+  ++ C +    +L+YI+  PI   ++ N+ F+  I+ +L  K +     E +   KA +A LIL P++G+  +L   +P+  +  +++ Y   +    QG L+   FCFFN E+   +K    + R+QF + A     RS +
Sbjct:   70 EPAHGKEGQ-FCNRTWDGWLCWGDVAAGIISEQRCPDYFQDFDPSEKVTKECGKNGHWFRHPDSNRTWTNYTRCNTFTHEKVKTALNLYYLTIIGHGLSIASLLISLGIFFYFKNLSCQRITLHKNLFFSFVCNS---IITIISLSAVANNQALVATNPVICKISQFIHLYLMGCNYFWMLCEGIYLHTLIVVAVFAEKQHLMWY-YLLGWGFPLIPACIHAVAR-SLYYNDNCWISSETHLLYIIHGPICAALLVNLFFLLNIVRVLITKLKVTHQAESNLYMKAVRATLILVPLLGIEFVLFPWKPEGRIAEEIYDYVMHILMHYQGLLVATIFCFFNGEVQAVLKRHWNQYRIQFGSFAHSEGLRSAS 434          
BLAST of Calcitonin family peptide receptor vs. UniProt/SwissProt
Match: sp|Q68EK2|CALRL_DANRE (Calcitonin gene-related peptide type 1 receptor OS=Danio rerio OX=7955 GN=calcrla PE=2 SV=1)

HSP 1 Score: 184.111 bits (466), Expect = 2.946e-51
Identity = 109/355 (30.70%), Postives = 190/355 (53.52%), Query Frame = 3
Query:  213 CRAIYDGLLCWNYTKAGLTVEQNCPALY-DFNVSALAYKSCLPSGEWLTKGGVNQSYTDYMACVPKASYS-------IYIYFVGYSMSIIALVISLAVLFYFKQLNCHRITLHKNMFFCNLMNSTGWLLYINVLSMHSNDSAVYS---MCQALYLIVNYTGTATYFWMLCEGLYL-LMILIFTFNKGQFIVRFCIILGWGAPLVIIILFGSLRFSVGASNLCHLDGFNNLMYIMLVPIFVTIIFNMIFMAFILGILFNKFRNHRNIEQHQGQKAAKAILILTPVMGLHSLLLLVQPDDAMWLKVHKYASALTNSLQGFLITMPFCFFNSEIHEAIKMR--RRRLQFTNKARLSNS 1235
            C   +DG LCW+ T+AG+T EQ+CP  + DF+ + +  K C  SG+W      N+++T++  C    +          Y+  +G+ +S+ +L ISL + F+FK L+C RITLHKN+FF  ++NS   ++++  ++  +N   V      C+    I  Y     YFWMLCEG+YL  +I++  F + Q ++ +  +LGWG PL+   +    R S   ++ C +    +L+YI+  PI   ++ N+ F+  I+ +L  K +     +     KA +A LIL P++G+  +LL  +P   +  +++ Y   +    QG L+   FCFFN E+   ++    + R+QF +    S++
Sbjct:   73 CNRTWDGWLCWDDTEAGITSEQHCPDYFQDFDPTEMVTKICTESGQWFLHPESNRTWTNFTRCNLHTTEGRRTAMNLFYLALIGHGLSLTSLFISLGIFFHFKSLSCQRITLHKNLFFSFVLNSIITIIWLTAVA--NNQELVQQNPISCKISQFIHLYIFGCNYFWMLCEGIYLHTLIVVAVFAEKQHLMWY-YLLGWGFPLIPATIHAVAR-SYYYNDNCWISSNTSLLYIIHGPICAAMLVNLFFLLNIVRVLITKLKVTHQAKSSLYMKAVRATLILVPLLGIQYVLLPYKPSGRVSAEIYDYIMHILMHYQGLLVATIFCFFNGEVQAVLRRHWNQYRIQFGSTITQSDA 423          
BLAST of Calcitonin family peptide receptor vs. TrEMBL
Match: A0A0K0PVL8 (DH31-like receptor 1 OS=Platynereis dumerilii OX=6359 PE=2 SV=1)

HSP 1 Score: 247.669 bits (631), Expect = 9.347e-74
Identity = 133/357 (37.25%), Postives = 204/357 (57.14%), Query Frame = 3
Query:  189 PPTDGQLYCRAIYDGLLCWNYTKAGLTVEQNCPALYD-FNVSALAYKSCLPSGEWLTKGGVNQSYTDYMACVPKASYS-----IYIYFVGYSMSIIALVISLAVLFYFKQLNCHRITLHKNMFFCNLMNSTGWLLYINVLSMHSND-SAVYSMCQALYLIVNYTGTATYFWMLCEGLYLLMILIFTFNKGQFIVRFCIILGWGAPLVIIILFGSLR-FSVGASNLCHLDGFNNLMYIMLVPIFVTIIFNMIFMAFILGILFNKFRNHRNIEQHQGQKAAKAILILTPVMGLHSLLLLVQPDDAM-WLKVHKYASALTNSLQGFLITMPFCFFNSEIHEAIKMR---RRRLQFTNKAR 1223
            P  + +LYC A +D   CWNYTKAG     +CP+  + F+ S  AYK C P G W      N+S+ +Y ACV   +       +YI+  GY++SI+ L++SL + FYF+QL C R+TLHKN+F   ++N   W+LY  + S+     S   + CQ L+++  Y  T  +FWM CEG YL  I++  F  G+ ++ FC I+GWGAP V  +++G+ R       N C +D  + L +I+L PI +TI+ N+ F+  I+ +L  K R   + + +Q +KA +A LIL P++GL  +LL  +P+D    L V+ + SAL  + QG  ++  FCFFN E+   +K +    R +Q     R
Sbjct:   26 PFQEDELYCNATWDEWGCWNYTKAGSRAFISCPSYKEGFDASLWAYKDCNPDGTWWLHPITNRSWANYTACVNMNALETDKRVVYIFVAGYAISIVFLLLSLIIFFYFRQLQCDRVTLHKNLFISYILNGIAWILYYTLASLDGEVLSENPAWCQFLHVVTQYFVTCNFFWMFCEGFYLHTIIVSAFTTGKTLIIFCFIVGWGAPFVSTVIYGAARGVYPSKRNECWMDE-SFLQWIVLGPILLTIVLNLFFLCNIVRVLITKLRAVNSPDTNQTRKAVRATLILIPLLGLQYILLPFRPNDGSPLLDVYLHVSALVTAFQGLFVSTIFCFFNGEVISVLKRKWGQHRLMQGNGTGR 381          
BLAST of Calcitonin family peptide receptor vs. TrEMBL
Match: R7T7Q8 (Uncharacterized protein OS=Capitella teleta OX=283909 GN=CAPTEDRAFT_221530 PE=3 SV=1)

HSP 1 Score: 233.802 bits (595), Expect = 8.662e-68
Identity = 131/380 (34.47%), Postives = 209/380 (55.00%), Query Frame = 3
Query:  186 PPPTDGQLYCRAIYDGLLCWNYTKAGLTVEQNCPALY-DFNVSALAYKSCLPSGEWLTKGGVNQSYTDYMACVPKASYS-----IYIYFVGYSMSIIALVISLAVLFYFKQLNCHRITLHKNMFFCNLMNSTGWLLYINVLSMHSNDSAVYSM-CQALYLIVNYTGTATYFWMLCEGLYLLMILIFTFNKGQFIVRFCIILGWGAPLVIIILFGSLR-FSVGASNLCHLDGFNNLMYIMLVPIFVTIIFNMIFMAFILGILFNKFRNHRNIEQHQGQKAAKAILILTPVMGLHSLLLLVQPDD-AMWLKVHKYASALTNSLQGFLITMPFCFFNSEIHEAIKMRRRRLQFTNKARLSNSRSKNIPRVRTPQTSLALGKSY 1298
            PPP DG+LYC   +D   CWNYT AG      CP+    F+ S  AY++C  +G W T    N+++++Y  CV  A  +     I ++  GY++SI+ L+ SL +  +FKQL C R+T+HK++F   + N   W+LY    +M +   A   + CQA+++I  Y  T  +FWM CEGLYL  I++  F+ G+ ++  C +LGW  P+ I  L+ + R  S   +  C L   + L +I+  PI +TI+ N IF+  I+ +L  K R+  + + +  +KA +A LIL P++GL  +L  ++P++   W +++   SA+  S QG  + + FCF N E+H  IK R       N+ R+   ++ N       QTS+A    Y
Sbjct:   23 PPPNDGRLYCDPYWDTWGCWNYTLAGTNAVIPCPSHQPGFDPSLTAYRTCSVNGTWWTHPVTNRTWSNYTTCVNHADLAKDKRVINVFIAGYTVSILFLIASLLIFTFFKQLQCDRVTIHKHLFTSYIFNGAVWILYYTTAAMDAQVQANNPVWCQAVHVITQYFVTCNFFWMFCEGLYLHTIIVVAFSTGKKLLICCYVLGWVLPIFITALYTAARALSPDEAKACWLHE-STLQWIVAGPIVLTIVINFIFLCNIVRVLVTKLRSVNSPDTNGYRKAVRATLILIPLLGLQFILFPLRPEENTTWDEIYMLVSAVVTSCQGLFVAVIFCFLNGEVHTVIKRRW------NQHRMMTQKALNPRGSFYTQTSMADPPPY 395          
BLAST of Calcitonin family peptide receptor vs. TrEMBL
Match: V4B1K4 (Uncharacterized protein OS=Lottia gigantea OX=225164 GN=LOTGIDRAFT_172709 PE=3 SV=1)

HSP 1 Score: 226.868 bits (577), Expect = 5.034e-65
Identity = 125/381 (32.81%), Postives = 213/381 (55.91%), Query Frame = 3
Query:  132 SFDYLELERTSCEAQMPPPPPTDGQLYCRAIYDGLLCWNYTKAGLTVEQNCPALYD--FNVSALAYKSCLPSGEWLTKGGVNQSYTDYMACV-PKASYSIY-IYFVGYSMSIIALVISLAVLFYFKQLNCHRITLHKNMFFCNLMNSTGWLLYINVLSMHS---NDSAVYSMCQALYLIVNYTGTATYFWMLCEGLYLLMILIFTFNKGQFIVRFCIILGWGAPLVIIILFGSLR-FSVGASNLCHLDGFNNLMYIMLVPIFVTIIFNMIFMAFILGILFNKFRNHRNIEQHQGQKAAKAILILTPVMGLHSLLLLVQPD-DAMWLKVHKYASALTNSLQGFLITMPFCFFNSEIHEAIKMRRRRLQFTNKARLSNSRSKN 1247
              +Y+E +R + E   P   P DG LYC A +D  +CW+YT AG TV Q CP  +D   N    A K C+  G WL      + +T+Y  C+  +A  S+  +Y  GY++SII L+I + +   F+QL C R+T+H+++F   ++    W++Y   + M+     D++++ +C  L+++  Y     Y WM CEG YL  +++  F K + ++   II+GW  P V  + +   R  SV  ++ C L   ++LM+ ++ P+ V++I N++F+  IL IL +K R     E HQ ++A +A+LIL P++GL  L++  +PD D   + + K  SA   S QG  + + FCFFN E+   +K +  +++ +N    S++R ++
Sbjct:   37 EINYVEQKRCN-ETIFPKGYPQDGGLYCNATFDDWMCWDYTPAGETVYQLCPIDFDTAMNPDGFAEKKCMEDGTWLRHHVSGRVWTNYTECINTEAENSVMMVYISGYALSIILLIICMVIFASFRQLKCTRVTIHQHLFLSFILAGMFWIIYYTQIPMNRQNMEDNSIWCIC--LHVVTQYLTICNYCWMFCEGFYLHTLIVLAFTKEKKLLWISIIIGWVFPTVPTVFYLGFRATSVFENSKCWLHK-SSLMWFIIGPVVVSLIVNLLFLVNILRILVSKLRAFNTNESHQNRRAVRAVLILIPLLGLQYLVIPFRPDHDPQAMHIFKLISAFLTSYQGVFVAVIFCFFNGEVITVMKRKWNQIRNSNYNPTSDNRRRS 413          
BLAST of Calcitonin family peptide receptor vs. TrEMBL
Match: A0A1S3K8Z3 (calcitonin gene-related peptide type 1 receptor isoform X2 OS=Lingula unguis OX=7574 GN=LOC106179577 PE=3 SV=1)

HSP 1 Score: 221.861 bits (564), Expect = 3.619e-63
Identity = 121/350 (34.57%), Postives = 193/350 (55.14%), Query Frame = 3
Query:  186 PPPTDGQLYCRAIYDGLLCWNYTKAGLTVEQNCPALY--DFNVSALAYKSCLPSGEWLTKGGVNQSYTDYMACVPKASYS-----IYIYFVGYSMSIIALVISLAVLFYFKQLNCHRITLHKNMFFCNLMNSTGWLLY-INVLSMHSNDSAVYSMCQALYLIVNYTGTATYFWMLCEGLYLLMILIFTFNKGQFIVRFCIILGWGAPLVIIILFGSLRFSV-GASNLCHLDGFNNLMYIMLVPIFVTIIFNMIFMAFILGILFNKFRNHRNIEQHQGQKAAKAILILTPVMGLHSLLLLVQPDDAMWLKVHKYASALTNSLQGFLITMPFCFFNSEIHEAIKMRRRRLQF 1208
            P PTDG LYC   +DG  CW+ T AG TV   CP     +++  A AYK C  +G W  +      +T Y  C+ +   +     +Y+Y  GY +S +A++ISL + F FKQL+C RIT+HKN+F   ++   GW++Y + V   H    +    CQ L+++V Y     YFWM CEGLYL  I++  F  G+ ++  C ++GWG P VI  ++ S+R  +  A++ C +   +   +I+   +  +++ N+ F+  I+ +L  K R   + + +QG+KA +A LIL P++GL  +L    P D+     +  ASA   S QGF + + +CF NSE+     +RR+  Q+
Sbjct:   73 PYPTDG-LYCYRTWDGWACWDDTPAGTTVYSPCPQYVSKEWDPLAQAYKECTSNGTWWRRPDTGAVFTKYFNCMDEEKMTENKSAVYVYLAGYGVSTLAILISLVIFFAFKQLHCDRITIHKNLFVSYVLTGVGWIIYYLKVPLDHDVIVSNPFWCQGLHVLVQYLTVCNYFWMFCEGLYLHTIIVVAFTTGKALLICCCVIGWGLPAVITFIYASVRGILRDATHECWIIN-SPYFWILNGTVAFSLLLNLAFLCNIVRVLMTKLRAVNSPDTNQGRKAVRATLILIPLLGLQFVLFPFTPSDSQTKTYYLIASAFVTSFQGFFVALIYCFLNSEVLTV--LRRKWEQY 418          
BLAST of Calcitonin family peptide receptor vs. TrEMBL
Match: A0A1S3K7X2 (calcitonin gene-related peptide type 1 receptor isoform X1 OS=Lingula unguis OX=7574 GN=LOC106179577 PE=3 SV=1)

HSP 1 Score: 221.861 bits (564), Expect = 5.125e-63
Identity = 121/350 (34.57%), Postives = 193/350 (55.14%), Query Frame = 3
Query:  186 PPPTDGQLYCRAIYDGLLCWNYTKAGLTVEQNCPALY--DFNVSALAYKSCLPSGEWLTKGGVNQSYTDYMACVPKASYS-----IYIYFVGYSMSIIALVISLAVLFYFKQLNCHRITLHKNMFFCNLMNSTGWLLY-INVLSMHSNDSAVYSMCQALYLIVNYTGTATYFWMLCEGLYLLMILIFTFNKGQFIVRFCIILGWGAPLVIIILFGSLRFSV-GASNLCHLDGFNNLMYIMLVPIFVTIIFNMIFMAFILGILFNKFRNHRNIEQHQGQKAAKAILILTPVMGLHSLLLLVQPDDAMWLKVHKYASALTNSLQGFLITMPFCFFNSEIHEAIKMRRRRLQF 1208
            P PTDG LYC   +DG  CW+ T AG TV   CP     +++  A AYK C  +G W  +      +T Y  C+ +   +     +Y+Y  GY +S +A++ISL + F FKQL+C RIT+HKN+F   ++   GW++Y + V   H    +    CQ L+++V Y     YFWM CEGLYL  I++  F  G+ ++  C ++GWG P VI  ++ S+R  +  A++ C +   +   +I+   +  +++ N+ F+  I+ +L  K R   + + +QG+KA +A LIL P++GL  +L    P D+     +  ASA   S QGF + + +CF NSE+     +RR+  Q+
Sbjct:   73 PYPTDG-LYCYRTWDGWACWDDTPAGTTVYSPCPQYVSKEWDPLAQAYKECTSNGTWWRRPDTGAVFTKYFNCMDEEKMTENKSAVYVYLAGYGVSTLAILISLVIFFAFKQLHCDRITIHKNLFVSYVLTGVGWIIYYLKVPLDHDVIVSNPFWCQGLHVLVQYLTVCNYFWMFCEGLYLHTIIVVAFTTGKALLICCCVIGWGLPAVITFIYASVRGILRDATHECWIIN-SPYFWILNGTVAFSLLLNLAFLCNIVRVLMTKLRAVNSPDTNQGRKAVRATLILIPLLGLQFVLFPFTPSDSQTKTYYLIASAFVTSFQGFFVALIYCFLNSEVLTV--LRRKWEQY 418          
BLAST of Calcitonin family peptide receptor vs. Ensembl Cavefish
Match: calcr (calcitonin receptor [Source:ZFIN;Acc:ZDB-GENE-060503-420])

HSP 1 Score: 186.808 bits (473), Expect = 1.863e-53
Identity = 116/359 (32.31%), Postives = 193/359 (53.76%), Query Frame = 3
Query:  189 PPTDGQLYCRAIYDGLLCWNYTKAGLTVEQNCPALY-DFNVSALAYKSCLPSGEWLTKGGVNQSYTDYMACVP------KASYSIY-IYFVGYSMSIIALVISLAVLFYFKQLNCHRITLHKNMFFCNLMNSTGWLLYINVLSMHSNDSAVYSM---CQALYLIVNYTGTATYFWMLCEGLYL-LMILIFTFNKGQFIVRFCIILGWGAPLVIIILFGSLRFSVGASNLCHLDGFNNLMYIMLVPIFVTIIFNMIFMAFILGILFNKFRNHRNIEQHQGQKAAKAILILTPVMGLHSLLLLVQPDDAMWLKVHKYASALTNSLQGFLITMPFCFFNSEIHEAIKMR--RRRLQFTNKAR 1223
            P     LYC   +DG LCW+ T AG    QNCP  + DF+ +  A K C  +G W      N+++++Y  C+       K +Y +Y +  VG+++SI +L+ISLA+ FYF+ L+C RITLHKN+F   ++NS      IN++ + +N   V      C+ L+    Y     YFWMLCEG+YL  +I++  F + Q +  +  +LGWG PLV   +    R      N C +    +L+Y++  PI   ++ N+ F+  I+ +L  K R+    E +   KA +A LIL P++G+  ++   +P++ +  +++ Y   +    QG L+   FCFFN E+   +K +  + ++Q+  + R
Sbjct:   40 PYNKSGLYCNRTWDGWLCWDDTPAGTYTTQNCPNYFPDFDPTEKATKYCDETGNWFRHPETNRTWSNYTHCIAYTKEKLKMAYILYYMAIVGHALSIASLLISLAIFFYFRSLSCQRITLHKNLFCSYVLNSA--FTIINLIFVVNNPKVVERNPVGCKVLHFFHMYMLGCNYFWMLCEGIYLHTLIVVAVFAEEQHL-HWYYLLGWGFPLVPASIHAVARKKYFDDN-CWMSVETHLLYVVHGPIVAALLVNLFFLLNIVRVLVTKLRDTHRAESNMYMKAVRATLILVPLLGIQFVIFPWRPENRLAGEIYDYIMHILLHYQGLLVATIFCFFNGEVQATLKRQWMQYKVQWGQRRR 394          
BLAST of Calcitonin family peptide receptor vs. Ensembl Cavefish
Match: ENSAMXT00000051776.1 (pep primary_assembly:Astyanax_mexicanus-2.0:13:4488382:4515609:1 gene:ENSAMXG00000038684.1 transcript:ENSAMXT00000051776.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 183.341 bits (464), Expect = 2.800e-52
Identity = 109/352 (30.97%), Postives = 192/352 (54.55%), Query Frame = 3
Query:  213 CRAIYDGLLCWNYTKAGLTVEQNCPA-LYDFNVSALAYKSCLPSGEWLTKGGVNQSYTDYMACVPKAS----YSIYIYF---VGYSMSIIALVISLAVLFYFKQLNCHRITLHKNMFFCNLMNSTGWLLYINVLSMHSNDSAVYSMCQALYLIVNYTGTATYFWMLCEGLYL-LMILIFTFNKGQFIVRFCIILGWGAPLVIIILFGSLRFSVGASNLCHLDGFNNLMYIMLVPIFVTIIFNMIFMAFILGILFNKFRNHRNIEQHQGQKAAKAILILTPVMGLHSLLLLVQPDDAMWLKVHKYASALTNSLQGFLITMPFCFFNSEIHEAIKMRRRRLQFTNKARLSNSRS 1241
            C   +DG LCW+Y + GLT  Q+CP   ++F+ S  A K C   G W      N+++T+Y +C    +     +I +Y+   +G+ +S+I L ISL + FYFK L+C RITLHKN+F   ++NST  +++   + +++ D    + C+    +  Y     YFWMLCEG+YL  +I++  F + Q ++ +  +LGWG PL+  ++    R S   ++ C +    +L+YI+  PI   ++ N+ F+  I+ +L  K +     E     KA +A LIL P++G+  +LL  +P+ ++  ++++Y   +  + QG L+   FCFFN E+   ++    + +      +SN  +
Sbjct:   42 CNRTWDGWLCWDYIQTGLTATQHCPDYFHNFDTSEEATKICTEDGYWFIHPESNRTWTNYTSCTKSTNEHRQVAINLYYLGLIGHGLSLIFLCISLGIFFYFKSLSCQRITLHKNLFSSFVLNSTITIIWFTAV-VNNQDLIQQTHCKVATFVHLYAFGCVYFWMLCEGIYLHTLIVVAVFAEKQHLMWY-YLLGWGFPLIPALIHAVAR-SYYFNDNCWISHNTSLLYIIHGPICAALLVNLFFLLNIVRVLITKLKVTHQAESSLYMKAVRATLILVPLLGIQFVLLPYKPEGSLSFEIYEYMMNILMNYQGLLVATIFCFFNGEVQGVLRRHWNQYRIQFGGTISNQEA 390          
BLAST of Calcitonin family peptide receptor vs. Ensembl Cavefish
Match: ENSAMXT00000037591.1 (corticotropin releasing hormone receptor 1 [Source:NCBI gene;Acc:103036295])

HSP 1 Score: 151.369 bits (381), Expect = 1.497e-40
Identity = 103/361 (28.53%), Postives = 176/361 (48.75%), Query Frame = 3
Query:  207 LYCRAIYDGL-LCWNYTKAGLTVEQNCPAL---YDFNVSALAYKSCLPSGEWLTKGGVNQSYTDYMACVPKAS-----YSIYIYFVGYSMSIIALVISLAVLFYFKQLNCHRITLHKNMFFCNLMNSTGWLLYINVLSMHSNDSAVYSMCQALYLIVNYTGTATYFWMLCEGLYLLMILIFTFNKGQFIVRFCIILGWGAPLVIII--LFGSLRFSVGASNLCHLDGFNNLMYIMLVPIFVTIIFNMIFMAFILGILFNKFRNHRNIEQHQGQKAAKAILILTPVMGLHSLLLLVQP-DDAMWLKVHKYASALTNSLQGFLITMPFCFFNSEIHEAIKMRRRRLQFTNKARLSNSRSKNIP 1253
            ++CR   DG+  CW  + AG  V + CP L     +N +   ++ CL +G W +KG  N S    +  V + S      ++ I ++G+ +S+  L+I+  +    + + C R  +H N+    ++ +  W +    +S   ++S V   C+ +  + NY   A +FWM  EG YL   ++ T++  +      I +GW  PL II+   FG L +           G     YI   P+ + ++ N IF+  I+ IL  K R     E  Q +KA KA L+L P++G+  +L  V P +D +   V  Y ++   S QGF +++ +CF NSE+  A++ R  R Q  +  R   +R+ +IP
Sbjct:   54 VFCRTSIDGIGTCWPRSMAGEMVSRPCPELLYGVRYNTTNKIFRKCLANGTWASKG--NYSQCKAILNVQRKSKLHYRIAVIINYMGHCLSLFTLLIAFTLFLRLRSIRCLRNIIHWNLISAFILRNATWFIVQLTMSPDVHESNV-PWCRLVTTLYNYFHMANFFWMFGEGCYLHTAIVLTYSTDRLKKWMFICIGWCIPLPIIVAWAFGKLYYDNEKCWFGKRAGVYT-DYIYQGPMILVLMINFIFLFNIVRILMTKLRASTTSETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDEVSQIVFIYFNSFLQSFQGFFVSVFYCFLNSEVRSAVRKRWHRWQDKHSIRTRVARAMSIP 410          
BLAST of Calcitonin family peptide receptor vs. Ensembl Cavefish
Match: pth2ra (parathyroid hormone 2 receptor [Source:NCBI gene;Acc:103034973])

HSP 1 Score: 151.754 bits (382), Expect = 8.401e-40
Identity = 99/367 (26.98%), Postives = 174/367 (47.41%), Query Frame = 3
Query:  213 CRAIYDGLLCWNYTKAGLTVEQNCPA-LYDFNVSALAYKSCLPSGEWLTKGGVNQSYTDYMACV----PKASYSIY------IYFVGYSMSIIALVISLAVLFYFKQLNCHRITLHKNMFFCNLMNSTGWLL---------------------YINVLSMHSNDSAVYSMCQALYLIVNYTGTATYFWMLCEGLYLLMILIFTF-NKGQFIVRFCIILGWGAPLVIIILFGSLRFSVGASNLCHLDGFNNLMYIMLVPIFVTIIFNMIFMAFILGILFNKFRN---HRNIEQHQGQKAAKAILILTPVMGLHSLLLLVQPD--DAMWLKVHKYASALTNSLQGFLITMPFCFFNSEIHEAIKMRRRR 1199
            C A +DGL+CW     G   +  CP  +YDFN +  AY+ C  +  WL    +N+++ +Y  C+    P     ++      +Y VGY++S  +L++++ ++ YF++L+C R  +H ++F   ++ +    +                     + N + +   D++ Y  C+   L+  Y     Y+W+L EGLYL  ++   F +  +++  F +I GWG P V +  +  +R +V  S    L    N+ +I  VPI   I  N I    I+ +L  K R     R   + Q +K AK+ L+L  V G+H ++ +  P   + +  +V  Y     NS QGF +++ +CF N E+   IK    R
Sbjct:   59 CPAEWDGLICWPRGYPGTLAKVPCPRYIYDFNHAGHAYRRCDSNSSWLLGESLNKTWANYTECIKSPGPNRERQVFFERLHIMYTVGYAVSFGSLLVAILIIGYFRRLHCTRNYIHMHLFVSFMLRAVSIFVKDRVVHTSAGLQEFDAVLMNNFTNAVDVAPVDTSQYMGCKVTVLLFIYFLATNYYWILVEGLYLHSLIFMAFLSDTKYLWGFTLI-GWGVPAVFVATWAIVRATVADSRCWELSA-GNIKWIYQVPILTAIGLNFILFVNIVRVLATKIRETNAGRYDTRKQYRKLAKSTLVLVLVFGVHYIVFVGMPHTIEGLGWEVRMYCELFFNSFQGFFVSIIYCFCNGEVQTEIKKTWTR 423          
BLAST of Calcitonin family peptide receptor vs. Ensembl Cavefish
Match: pth2ra (parathyroid hormone 2 receptor [Source:NCBI gene;Acc:103034973])

HSP 1 Score: 151.369 bits (381), Expect = 9.006e-40
Identity = 99/367 (26.98%), Postives = 174/367 (47.41%), Query Frame = 3
Query:  213 CRAIYDGLLCWNYTKAGLTVEQNCPA-LYDFNVSALAYKSCLPSGEWLTKGGVNQSYTDYMACV----PKASYSIY------IYFVGYSMSIIALVISLAVLFYFKQLNCHRITLHKNMFFCNLMNSTGWLL---------------------YINVLSMHSNDSAVYSMCQALYLIVNYTGTATYFWMLCEGLYLLMILIFTF-NKGQFIVRFCIILGWGAPLVIIILFGSLRFSVGASNLCHLDGFNNLMYIMLVPIFVTIIFNMIFMAFILGILFNKFRN---HRNIEQHQGQKAAKAILILTPVMGLHSLLLLVQPD--DAMWLKVHKYASALTNSLQGFLITMPFCFFNSEIHEAIKMRRRR 1199
            C A +DGL+CW     G   +  CP  +YDFN +  AY+ C  +  WL    +N+++ +Y  C+    P     ++      +Y VGY++S  +L++++ ++ YF++L+C R  +H ++F   ++ +    +                     + N + +   D++ Y  C+   L+  Y     Y+W+L EGLYL  ++   F +  +++  F +I GWG P V +  +  +R +V  S    L    N+ +I  VPI   I  N I    I+ +L  K R     R   + Q +K AK+ L+L  V G+H ++ +  P   + +  +V  Y     NS QGF +++ +CF N E+   IK    R
Sbjct:   49 CPAEWDGLICWPRGYPGTLAKVPCPRYIYDFNHAGHAYRRCDSNSSWLLGESLNKTWANYTECIKSPGPNRERQVFFERLHIMYTVGYAVSFGSLLVAILIIGYFRRLHCTRNYIHMHLFVSFMLRAVSIFVKDRVVHTSAGLQEFDAVLMNNFTNAVDVAPVDTSQYMGCKVTVLLFIYFLATNYYWILVEGLYLHSLIFMAFLSDTKYLWGFTLI-GWGVPAVFVATWAIVRATVADSRCWELSA-GNIKWIYQVPILTAIGLNFILFVNIVRVLATKIRETNAGRYDTRKQYRKLAKSTLVLVLVFGVHYIVFVGMPHTIEGLGWEVRMYCELFFNSFQGFFVSIIYCFCNGEVQTEIKKTWTR 413          
BLAST of Calcitonin family peptide receptor vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000542.1 (pep scaffold:Pmarinus_7.0:GL476735:164228:192153:1 gene:ENSPMAG00000000476.1 transcript:ENSPMAT00000000542.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 171.785 bits (434), Expect = 1.251e-48
Identity = 108/347 (31.12%), Postives = 184/347 (53.03%), Query Frame = 3
Query:  186 PPPTDGQLYCRAIYDGLLCWNYTKAGLTVEQNCPALY-DFNVSALAYKSCLPSGEWLTKGGVNQSYTDYMAC-------VPKASYSIYIYFVGYSMSIIALVISLAVLFYFKQLNCHRITLHKNMFFCNLMNSTGWLLYINVLSMHSNDSAVYSM---CQALYLIVNYTGTATYFWMLCEGLYL-LMILIFTFNKGQFIVRFCIILGWGAPLVIIILFGSLRFSVGASNLCHLDGFNNLMYIMLVPIFVTIIFNMIFMAFILGILFNKFRNHRNIEQHQGQKAAKAILILTPVMGLHSLLLLVQPDDAMWLKVHKYASAL--TNSLQGFLITMPFCFFNSEIHEAIK 1184
            PP +  + +C   +DG LCW  T AG    Q+CP  + DF++     K C   G+W      N+++++Y  C       +  A    Y+   G+ +SI+ L++SL + FYFK L+C RITLHKN+F   ++NS   +  I + ++ +N   V S    C+ L     Y     YFWMLCEG+YL  +I++  F + Q +  +  +LGWG P+V  ++    R ++   + C +    +L+YI+  P+   ++ N+ F+  I+ +L  K +     E     KA +A LIL P++G+  +L+  +P+  +  +++ Y   +  T+ +QGFL+   FCF N E+  A+K
Sbjct:   32 PPYSVSRKHCNRTWDGWLCWGDTMAGDVAVQHCPDYFPDFDLQEKVTKICNTDGQWFRHPDSNRTWSNYTLCNAFTADKLKMAVNLFYLAVTGHGVSILVLLVSLTIFFYFKSLSCQRITLHKNLFMSYILNSI--ITIIQLTAVANNQELVASKPVWCKVLQFFHQYMMGCNYFWMLCEGIYLHTLIVVAVFAEKQHLFWY-YLLGWGFPIVPALMHAVAR-TIYYDDNCWISSATHLLYIIHGPVVAALLVNLFFLLNIVRVLVTKLKVTHRAETSMYMKAVRATLILVPLLGIQFVLVPWKPERFV-GEIYDYIMQIFPTHLIQGFLVATIFCFCNGEVQAALK 373          
BLAST of Calcitonin family peptide receptor vs. Ensembl Sea Lamprey
Match: pth1r (parathyroid hormone 1 receptor [Source:ZFIN;Acc:ZDB-GENE-991123-8])

HSP 1 Score: 159.458 bits (402), Expect = 3.976e-44
Identity = 110/401 (27.43%), Postives = 184/401 (45.89%), Query Frame = 3
Query:  144 LELERTSCEAQMPPPPPTDGQLYCRAIYDGLLCWNYTKAGLTVEQNCPA-LYDFNVSALAYKSCLPSGEWLTKGGVNQSYTDYMACVP--------KASYSIY----IYFVGYSMSIIALVISLAVLFYFKQLNCHRITLHKNMFFCNLMNSTGWLLYINVL-------------SMHSNDSAVYSMCQALYLIVNYTGTATYFWMLCEGLYLLMILIFTFNKGQFIVRFCIILGWGAPLVIIILFGSLRFSVGASNLCHLDGFNNLMYIMLVPIFVTIIFNMIFMAFILGILFNKFRN---HRNIEQHQGQKAAKAILILTPVMGLHSLLLLVQP-DDAMWL--KVHKYASALTNSLQGFLITMPFCFFNSEIHEAIKMRRRRLQFTNK-ARLSNSRSKN 1247
            L   +T CE  +     +    +C A +DGL+CW +   G  V + CP+ +YDFN    AY+ C  +G W      N+ + +Y  C          K   SI+    +Y +GYS+S+ +L I+L +L  F++L+C R  +H ++F   ++ +    +   VL             S  +    +++ C+ +  +  Y    +YFW+L EGLYL  ++  TF+    +  F +I GWG P+V + ++ + R ++  S    L     L +I   PI   +  N +    I+ +L  K R     R   + Q +K  K+ L+L P+ G+H +L    P  D + L  ++  Y     NS QGF + + +CF N E+   +K    R        R S S S N
Sbjct:   25 LTEAKTHCEKTIHSTNASSADTHCTAEWDGLICWPWGLPGSMVREKCPSYIYDFNAHGHAYRKCESNGTW-KMSTANRLWANYSECTEFLNPHVQAKEKESIHRLSILYTIGYSVSLASLAIALCILTVFRRLHCTRNYIHMHLFVSFMLRAASIFVKDGVLYSDNELRLATPGPSPPAEAPHIFAGCRVVVTLFLYCLATSYFWVLVEGLYLYSLIFLTFSASGRLWTFALI-GWGFPVVFVFVWAAARATLANSQCWDLSA-GWLKWIYQAPILAAVAVNFVLFVNIVRVLATKLRETNAARQESRQQYRKLLKSTLVLMPLFGVHYVLFAAMPYTDVIGLAWQIQMYYEMTFNSFQGFFVAIIYCFCNGEVRGEMKKLWSRWSLDQALKRRSGSCSYN 422          
BLAST of Calcitonin family peptide receptor vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004899.1 (pep scaffold:Pmarinus_7.0:GL476767:721819:758871:-1 gene:ENSPMAG00000004402.1 transcript:ENSPMAT00000004899.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 136.346 bits (342), Expect = 8.022e-36
Identity = 90/365 (24.66%), Postives = 174/365 (47.67%), Query Frame = 3
Query:  213 CRAIYDGL-LCWNYTKAGLTVEQNCPALYD---FNVSALAYKSCLPSGEWLTKGGVNQSYTDYMACVPKASY---SIYIYFVGYSMSIIALVISLAVLFYFKQLNCHRITLHKNMFFCNLMNSTGWLLY--INVLSMHSNDSAVYSMCQALYLIVNYTGTATYFWMLCEGLYLLMILIFTFNKGQFIVRFCIILGWGAPLVIIILFGSLRF-------SVGASNLCHLDGFNNLMYIMLVPIFVTIIFNMIFMAFILGILFNKFRNHRNIEQHQ-GQKAAKAILILTPVMGLHSLLLLVQP-DDAMWLKVHKYASALTNSLQGFLITMPFCFFNSEIHEAIKMRRRRLQFTNKARLSNSRSKNIP 1253
            C A  D +  CW  ++AG TV   CP  ++   ++ S    + CL +G W  +   +       A  P + +   ++ + ++G+ +S+ AL+ +    ++ + + C R  +H ++    ++ +  WLL   I++ +   N+      C+ +  + NY     +FWM  EG YL   ++ T++  +      + +GW  P  III++  ++          G +   ++D      YI   PI + ++ N IF+  I+ IL  K R     E  Q  +KA KA L+L P++G+  +L  V P +D +   +  Y ++   S QGF +++ +CF N E+  A++ R  R    ++ +   +R+ +IP
Sbjct:   42 CNATRDEIGTCWPESEAGRTVATPCPERFNGVRYDSSKSVIRECLANGTWAQRSNYSLCKPIIDAKKPNSQHYKIALIVNYLGHCISLAALITAFGFFWWLRSIRCLRNAIHWHLVTTFILRNAAWLLLQIIDLSTQERNEP----WCRVVITVFNYFQVTNFFWMFVEGCYLHTAIVMTYSTDKLRKSIFVCIGWCIPAPIIIVWAMVKLFYEDEKCWFGKTEGKYID------YIYQGPIILVLLVNFIFLFNIVRILMTKLRASTTSETIQYSRKAVKATLVLLPLLGITYMLFFVNPGEDPVSQVIFIYVNSFLMSFQGFFVSVFYCFLNGEVRSALRKRWNRWMDNHRLQARVTRAMSIP 396          
BLAST of Calcitonin family peptide receptor vs. Ensembl Sea Lamprey
Match: ENSPMAT00000009958.1 (pep scaffold:Pmarinus_7.0:GL477206:37870:64312:-1 gene:ENSPMAG00000008983.1 transcript:ENSPMAT00000009958.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 120.553 bits (301), Expect = 1.991e-30
Identity = 88/366 (24.04%), Postives = 168/366 (45.90%), Query Frame = 3
Query:  210 YCRAIYDGL-LCWNYTKAGLTVEQNCPALYD---FNVSALAYKSCLPSGEWLTKGGVNQSYTDYMACVPKAS----YSIYIYFVGYSMSIIALVISLAVLFYFKQLNCHRITLHKNMFFCNLMNSTGWLLY--INVLSMHSNDSAVYSMCQALYLIVNYTGTATYFWMLCEGLYLLMILIFTFNKGQFIVRFCIILG-------WGAPLVIIILFGSLRFSVGASNLCHLDGFNNLMYIMLVPIFVTIIFNMIFMAFILGILFNKFRNHRNIEQHQGQKAAKAILILTPVMGLHSLLLLVQP-DDAMWLKVHKYASALTNSLQGFLITMPFCFFNSEIHEAIKMRRRRLQFTNKARLSNSRSKNIP 1253
            +C A  D +  CW  ++A   V + CP  ++   ++ S   Y+ C+    W  +   N S  + +    + S     ++ + ++G+ +S++AL+ +  + +  + + C R  +H N+    ++ +  W L   I++ +   N+      C  +  I NY     +FWM  EG YL   ++ T++  +      I +G            ++ + F   +   G +   ++D      YI   PI + ++ N IF+  I+ IL  K R     E  Q +KA KA L+L P++G+  +L  V P +D +   +  Y ++   S QGF +++ +CF N E+  AI+ R  R    +  R   +R+ +IP
Sbjct:   12 FCNATRDEIGTCWPSSEASRVVIRPCPDRFNGVQYDTSKSVYRECMADATWARRS--NYSLCEAIILSKRNSQHYKVALVVNYLGHCVSLLALMTAFTIFWCLRSIRCLRNAIHWNLMTTFILRNATWFLLQLIDLSTQERNEP----WCCIIITIFNYFQVTNFFWMFVEGCYLHTAIVMTYSTDKLRKWIFICIGWVIPAPIIIIWAMVKLHFEDEKCWFGKTPGKYID------YIYQGPIILVLLINFIFLFNIVTILMTKLRASTTSETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDEISQVIFLYVNSFLMSFQGFFVSVFYCFLNGEVRSAIRKRWHRWLDNHAIRARVTRAMSIP 365          
BLAST of Calcitonin family peptide receptor vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004243.1 (pep scaffold:Pmarinus_7.0:GL484465:15708:23345:-1 gene:ENSPMAG00000003877.1 transcript:ENSPMAT00000004243.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 106.301 bits (264), Expect = 7.885e-26
Identity = 75/314 (23.89%), Postives = 138/314 (43.95%), Query Frame = 3
Query:  117 SFQNDSFDYLELERTSCEAQMPPPPPTDGQLYCRAIYDGLLCWNYTKAGLTVEQNCPA---LYDFNVSALAYKSCLPSGEWLTKGGVNQSYTDYMACVP---------KASYSIY----IYFVGYSMSIIALVISLAVLFYFKQLNCHRITLHKNMFFCNLMNSTGWLLYINVLSMHSNDSAV-------------YSMCQALYLIVNYTGTATYFWMLCEGLYLLMILIFTFNKGQFIVRFCIILGWGAPLVIIILFGSLRFSVGASNLCHLDGFNNLMYIMLVPIFVTIIFNMIFMAFILGILFNKFRNHRN 971
            S   D+        T C+ Q+    P    +YC   +D   CW  +     V   CP+     D       Y+ C   G WLT+  V  ++ D+  C+          K  Y ++    +Y  GYS+S+ +LV+++ +L  F++L+C R  +H N+F   ++ +   LL    L+ +                   Y+ C+A ++ + Y   A YFW+L EG YL  +L       + ++ F ++LGWG P++ II +   +          ++ +  + +++  PI  +I+ N I    I+ IL +K +  ++
Sbjct:    2 SLLQDTLHRWSSYATECK-QLHDSEPFLSGVYCNRTFDHYACWPDSLPDTKVAIPCPSYLPWIDKVEGGYVYRYCTRDGTWLTQDNVTAAWRDHSECLDDENNISTEGKEMYLLHALRLVYTTGYSVSLASLVVAMGILIMFRRLHCTRNYIHMNLFASFILRAISVLLKDAALTHNYTKRPQNASDWLGYFGYEGYTGCRATHVFMQYCIGANYFWLLVEGSYLHTLLTMCVFTKKKLIAFYVLLGWGTPIMFIIPWMVSKLIYENQGCWGINTWMGIWWLIRGPILFSIVVNCILFVKIIKILLSKLKAQQS 314          
BLAST of Calcitonin family peptide receptor vs. Ensembl Nematostella
Match: EDO34537 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SP31])

HSP 1 Score: 87.0409 bits (214), Expect = 4.072e-19
Identity = 73/292 (25.00%), Postives = 136/292 (46.58%), Query Frame = 3
Query:  303 NVSALAYKSCLPSGEWLTKGGVNQSYTDYMACVPKASYSIYIYFVGYSMSIIALVISLAVLFYFKQLNCHRITLHKNMFFCNLMNSTGWLLYINVLSMHSNDSAVYSMCQALYLIVNYTGTATYFWMLCEGLYLLMILIFTFNKGQFIVRFCIILGWGAPLVIIILFGSLR-FSVGASNLCHLDGFNNLMYIMLVPIFVTIIFNMIFMAFILGILFNKFRNHRNIEQHQGQKAAKAILILTPVMGLH--SLLLLVQPDDAMWLKVHKYASALTNSLQGFLITMPFCFFNSEI 1169
            N S+  +  CL     LT   V   +TD     P+      I ++G  +S +AL+I+L +    + L+  R  +H N+     +     +L+++ ++   N       CQ +   ++Y  T  + WML EG++L + ++  F      +    I GWG P VI+ +  +++  S G  ++C L   ++ ++  + P+   I  N + +  ++  + N     +N +    +   K  L+L P++G+   S LL V  D   +    +Y  A+TNS QGFLI +    FN+E+
Sbjct:    9 NSSSDNHVECLT--HHLTSFAVLMQHTDIPLTEPEKLSLQIITYIGCGISSVALLITLVIFLSIESLSTERHRIHLNLVLALFLAQ---ILFLSGINATGNKIG----CQVVAAFLHYFYTVAFTWMLNEGVHLYLKVVKVFRIENVRLLHYYIFGWGFPAVIVGISAAIKPNSYGTESICWLSLSDDFVWAFIGPVTFIIAINCLILIVVVKTIVNSASTVKNSDHAHIRAGVKGALVLMPLLGVSWISGLLAVNKDTVFF----QYVFAITNSFQGFLIFLLHVVFNTEV 287          
BLAST of Calcitonin family peptide receptor vs. Ensembl Nematostella
Match: EDO42800 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S0A5])

HSP 1 Score: 79.7221 bits (195), Expect = 9.359e-16
Identity = 70/273 (25.64%), Postives = 134/273 (49.08%), Query Frame = 3
Query:  426 IYFVGYSMSIIALVISLAVLFYFKQLNCHRITLHKNMFFCNLMNSTGWLLYINVLSMHSNDSAVYSMCQALYLIVNYTGTATYFWMLCEGLYLLMILIFTFNKGQFIVRFCIILGWGAPLVIII--------LFGSLRFSVGASNLCHLDGFNNLMYIMLVPIFVTIIFNMIFMAFILG--ILFNKFRNHRNIEQHQGQKAAKAILILTPVMGLHSLLLLVQPDDAMWLKVHKYASALTNSLQGFLITMPFCFFNSEIHEAIKMRRRRLQFTN 1214
            I ++G  +S++   I++A    F  +   RI +  N+   NLM      L   VL    N +   ++C  +  +V +T TA++ WML EG YL  +++  FN     +R+C  + +G P ++++        L G ++  V ++N+C ++  N+++++   P+      NM+ +  ++   IL        +      + +A+AI++LTP++G+  L  L+         V  Y   + NS QGF+I +  C  NSE+  A  +R  +L+ +N
Sbjct:  445 ISYIGLILSLLGEAITVAAYLSFLNVRKDRIQIRLNLIV-NLM------LAQIVLIAGLNVTGHKTLCLVVVALVQFTYTASFCWMLVEGCYLYRVIVKVFNY-HIDLRYCYAISYGFPTLMVVAALLYAYLLTGEIQGYV-STNVCWMNYDNHVIWMFAGPVIFIATVNMLVLGCVVKEMILLPTVDPENSRTSENIRSSARAIVVLTPLLGITWLFGLLSLSGIGV--VGDYIFTILNSSQGFMIFIFHCVRNSELKAAFNLRVYQLESSN 706          
BLAST of Calcitonin family peptide receptor vs. Ensembl Nematostella
Match: EDO32467 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SV16])

HSP 1 Score: 74.7146 bits (182), Expect = 1.447e-15
Identity = 50/185 (27.03%), Postives = 92/185 (49.73%), Query Frame = 3
Query:  624 MCQALYLIVNYTGTATYFWMLCEGLYLLMILIFTFNKGQFIVRFCIILGWGAPLVIIILFGSLRFS-VGASNLCHLDGFNNLMYIMLVPIFVTIIFNMIFMAFILGILFNKFRNHRNIEQHQGQKAAKAILILTPVMGLHSL--LLLVQPDDAMWLKVHKYASALTNSLQGFLITMPFCFFNSEI 1169
            +C+ + L+++Y  +A++ WM  EG +L M ++  F      +++  I GWG P +++ +  S+  S  G    C L      ++  L P+   I+ N + ++ ++ I+     +    E  Q     K  L+L P++G+  +  LL V  +      V +Y  A++NSLQGF I +  C  NSE+
Sbjct:   17 LCRIVALMLHYLFSASFTWMCIEGFHLYMKIVTVFGAEGVKLKYYYIFGWGFPAIMVGVAASVDSSGYGTRAACWLSMDKGFIWAFLGPVVAIILVNCVILSMVVKIVMTSSASQSEPEYRQILAGVKGALVLLPLLGITWVFGLLAVTKETV----VFQYVFAISNSLQGFCIFIFQCIGNSEV 197          
BLAST of Calcitonin family peptide receptor vs. Ensembl Nematostella
Match: EDO39196 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SAS3])

HSP 1 Score: 76.6406 bits (187), Expect = 1.539e-15
Identity = 63/256 (24.61%), Postives = 122/256 (47.66%), Query Frame = 3
Query:  411 SYSIYIYFVGYSMSIIALVISLAVLFYFKQLNCHRITLHKNMFFCNLMNSTGWLLYINVLSMHSNDSAVYSMCQALYLIVNYTGTATYFWMLCEGLYLLMILIFTFNKGQFIVRFCIILGWGAPLVIIIL-FGSLRFSVGASNLCHLDGFNNLMYIMLVPIFVTIIFNMIFMAFILGILFNKFRNHRNIEQHQ--GQKAAKAILILTPVMGLHSLLLLVQPDDAMWLKVHKYASALTNSLQGFLITMPFCFFNSEI 1169
             Y  YI F+G  +SI   V+++    +   L   R+ +H N+    L      +L+I V + H       S+C ++ +++ +   + + WML EG+++  ++I  FN G+   +   ++GWG  L I      + R S   S+ C L   +  ++  + P  V I FN++ +  +L +     ++      +    +   KA + L P++GL  L   +  ++     + +Y  A+ NS+QGFLI + +C  +SE+
Sbjct:   52 DYLTYITFIGLGLSIAGCVLTILTHLFLPSLRSERVFIHINLVTAILFAQ---ILFI-VGATHREPQ---SLCLSVAVLLYFFYMSVFTWMLVEGIHIYCLVIRVFNSGRGRKKIYTVIGWGEFLSIFPSGMPAFRNSSTTSSRCWLSLESGAIWAFVAPALVVIAFNLVILFMVLRVTAVMLKDESQTSSNVCLSRALVKAFVTLLPILGLTWLFGFLAFNNKT--VMFEYLFAIFNSMQGFLIFVFYCLLSSEV 298          
BLAST of Calcitonin family peptide receptor vs. Ensembl Nematostella
Match: EDO29167 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T4E6])

HSP 1 Score: 73.9442 bits (180), Expect = 1.940e-15
Identity = 49/182 (26.92%), Postives = 95/182 (52.20%), Query Frame = 3
Query:  627 CQALYLIVNYTGTATYFWMLCEGLYLLMILIFTFNKGQFIVRFCIILGWGAPLVIIILFGSLRFS-VGASNLCHLDGFNNLMYIMLVPIFVTIIFNMIFMAFILGILFNKFRNHRNIEQHQGQKAAKAILILTPVMGLHSLLLLVQPDDAMWLKVHKYASALTNSLQGFLITMPFCFFNSEI 1169
            C+ + L ++Y  TA + WM CEG++L   +I  F+     +++  +LGWGAPL+I+I+  ++RF   G+   C +   + L++  + P+   +  N + M  ++ ++     +  ++     +   K +++L P++GL  +  L+  D+       +Y  A+ NSLQG  I    C  NSE+
Sbjct:    3 CKVVALSLHYLYTAAFAWMCCEGVHLYTKVIEVFSSEGSKMKYYYLLGWGAPLIIVIISAAIRFEHYGSEQACWISIKDGLIWAFVGPVLAIMAVNFVVMVMVIKVILASMLDLTHLMTFLYRAGLKGMVVLLPLLGLTWVFGLMAVDEKT--IAFQYIFAILNSLQGLFIFAFHCIGNSEV 182          
BLAST of Calcitonin family peptide receptor vs. Ensembl Medaka
Match: calcr (calcitonin receptor [Source:NCBI gene;Acc:101174680])

HSP 1 Score: 190.66 bits (483), Expect = 5.944e-55
Identity = 122/387 (31.52%), Postives = 205/387 (52.97%), Query Frame = 3
Query:  168 EAQMPPPPPTDGQLYCRAIYDGLLCWNYTKAGLTVEQNCPALYD-FNVSALAYKSCLPSGEWLTKGGVNQSYTDYMACVP------KASYSI-YIYFVGYSMSIIALVISLAVLFYFKQLNCHRITLHKNMFFCNLMNSTGWLLYINVLSMHSNDSAVYSM---CQALYLIVNYTGTATYFWMLCEGLYL-LMILIFTFNKGQFIVRFCIILGWGAPLVIIILFGSLRFSVGASNLCHLDGFNNLMYIMLVPIFVTIIFNMIFMAFILGILFNKFRNHRNIEQHQGQKAAKAILILTPVMGLHSLLLLVQPDDAMWLKVHKYASALTNSLQGFLITMPFCFFNSEIHEAIKMRRRRLQFTNKARLSNSRSKNIPRVRTPQTSLALGK 1292
            E     PP      +C   +DG LCW  T AG    QNCP  +D F+ +  A K C   G+W      N+++++Y  C        K++Y + Y+  VG+++SI +L+ISLA+ FYF+ L+C RITLHKN+FF  ++NS   ++Y+  +++ +N   V      C+ L+    Y     YFWMLCEG+YL  +I++  F + Q +  +  +LGWG PLV + +    R      N C +    +L+Y +  PI   ++ N+ F+  I+ +L  K R+    E +   KA +A LIL P++G+  ++   +P++ +  +V++Y   +    QG L+   FCFFN E+  A+K  R+ +Q+  K +    R  +     T  T+ ++ +
Sbjct:   30 EKMHRDPPYNKSGPFCSRNWDGWLCWEDTPAGTFAAQNCPNYFDDFDPTEKATKYCGEDGQWFRHPDTNRTWSNYTLCNENTKAKLKSAYILFYMAIVGHALSIASLLISLAIFFYFRSLSCQRITLHKNLFFSYVLNSALTIIYL--VTVVNNPEVVARNPVGCKVLHFFHMYMLGCNYFWMLCEGIYLHTLIVVAVFAEEQHL-HWYYLLGWGFPLVPVSIHAVARKKYFDDN-CWMSVETHLLYAVHGPIVAALLVNLFFLLNIIRVLVTKLRDTHRAESNMYMKAVRATLILVPLLGIQFVIFPWRPENRLAGEVYEYVMHILMHYQGLLVATIFCFFNGEVQGALK--RQWMQY--KTQWGQRRKDHCSMRSTSYTATSITE 408          
BLAST of Calcitonin family peptide receptor vs. Ensembl Medaka
Match: ENSORLT00000000113.2 (calcitonin gene-related peptide type 1 receptor [Source:NCBI gene;Acc:101172311])

HSP 1 Score: 188.734 bits (478), Expect = 4.484e-54
Identity = 115/344 (33.43%), Postives = 189/344 (54.94%), Query Frame = 3
Query:  213 CRAIYDGLLCWNYTKAGLTVEQNCPALY-DFNVSALAYKSCLPSGEWLTKGGVNQSYTDYMACVPKASYS--------IYIYFVGYSMSIIALVISLAVLFYFKQLNCHRITLHKNMFFCNLMNSTGWLLYINVLSMHSNDSAVYSMCQALYLIVNYTGTATYFWMLCEGLYL-LMILIFTFNKGQFIVRFCIILGWGAPLVIIILFGSLRFSVGASNLCHLDGFNNLMYIMLVPIFVTIIFNMIFMAFILGILFNKFRNHRNIEQHQGQKAAKAILILTPVMGLHSLLLLVQPDDAMWLKVHKYASALTNSLQGFLITMPFCFFNSEIHEAIKMRR--RRLQF 1208
            C   +DG LCW+ ++ G   EQNCP  Y DF+  A+A K C  +GEW      N+++TD+  C    ++          Y+  +G+ +S+++L++SL + FYFK L+C RITLHKN+FF  ++NS   ++ +    +   D+A    C+ L  I  YT +  YFWMLCEG+YL  +I++  F + Q ++ +  +LGWG PLV  +++   R     ++ C +    +L+YI+  PI   ++ N  F+  I+ IL  K R     E     +A +A LIL P++G+  +LL  +P D    +++ Y   +    QG L++  FCFFN E+   ++     +R+QF
Sbjct:   65 CNMTWDGWLCWDESEPG-EKEQNCPGYYKDFDTQAMATKVCTDTGEWGRHPTSNRTWTDFRNCQANVTHHGAQAAMTHFYLIMIGHGLSLVSLLMSLGIFFYFKSLSCQRITLHKNLFFSFVLNS---VVTVTWFLVQKEDTA---SCKLLSFIQMYTMSCNYFWMLCEGIYLHTLIVVAVFAEKQHLLWY-YLLGWGFPLVPAVIYSIAR-QCYYNDKCWVSPATSLLYIIHAPICAALVVNFFFLLNIVRILITKLRVTHQAESSLYMRAVRATLILIPLLGIQYVLLAYKPHDHWIAEIYLYIMNILMHHQGLLVSTIFCFFNGEVQTVLRRHWNLQRMQF 399          
BLAST of Calcitonin family peptide receptor vs. Ensembl Medaka
Match: calcrla (calcitonin receptor like receptor [Source:NCBI gene;Acc:101158808])

HSP 1 Score: 186.037 bits (471), Expect = 5.469e-53
Identity = 111/344 (32.27%), Postives = 185/344 (53.78%), Query Frame = 3
Query:  213 CRAIYDGLLCWNYTKAGLTVEQNCPALY-DFNVSALAYKSCLPSGEWLTKGGVNQSYTDYMACVPKASYS-------IYIYFVGYSMSIIALVISLAVLFYFKQLNCHRITLHKNMFFCNLMNSTGWLLYINVLSMHSNDSAVY---SMCQALYLIVNYTGTATYFWMLCEGLYL-LMILIFTFNKGQFIVRFCIILGWGAPLVIIILFGSLRFSVGASNLCHLDGFNNLMYIMLVPIFVTIIFNMIFMAFILGILFNKFRNHRNIEQHQGQKAAKAILILTPVMGLHSLLLLVQPDDAMWLKVHKYASALTNSLQGFLITMPFCFFNSEIHEAIKMRRRRLQF 1208
            C   +DG LCW+ T AG+T EQ+CP  + DF+ S +  K C  +G W      N+++T+Y  C    +          Y+  +G+ +S+++L ISLA+ F+FK L+C RITLHKN+FF  ++NS   ++++  ++  +N   V    + C+    I  Y     YFWMLCEG+YL  +I++  F + Q ++ +  +LGWG PL+   +    R S   ++ C +    +L+YI+  PI   ++ N+ F+  I+ +L  K +     E     KA +A LIL P++G+  +LL  +P   +  +++ Y   +    QG L+   FCFFN E+     +RR   Q+
Sbjct:   63 CNRTWDGWLCWDDTAAGVTSEQHCPDYFQDFDPSEMVTKICTENGHWFLHPESNRTWTNYTRCNEHTNEGRMTAMNLFYLALIGHGLSLVSLFISLAIFFHFKSLSCQRITLHKNLFFSFVLNSVITIIWLTAVA--NNQELVQRNPTSCKVSMFIHLYLFGCNYFWMLCEGIYLHTLIVVAVFAEKQHLMWY-YLLGWGFPLIPASIHAIAR-SYYYNDNCWISSKTSLLYIIHGPICAALVVNVFFLLNIVRVLITKLKVTHQAESSLYMKAVRATLILVPLLGIQYVLLPYKPGGRVSSEIYDYIMHILMHYQGLLVATIFCFFNGEVQAV--LRRHWNQY 400          
BLAST of Calcitonin family peptide receptor vs. Ensembl Medaka
Match: calcrla (calcitonin receptor like receptor [Source:NCBI gene;Acc:101158808])

HSP 1 Score: 186.037 bits (471), Expect = 6.749e-53
Identity = 111/344 (32.27%), Postives = 185/344 (53.78%), Query Frame = 3
Query:  213 CRAIYDGLLCWNYTKAGLTVEQNCPALY-DFNVSALAYKSCLPSGEWLTKGGVNQSYTDYMACVPKASYS-------IYIYFVGYSMSIIALVISLAVLFYFKQLNCHRITLHKNMFFCNLMNSTGWLLYINVLSMHSNDSAVY---SMCQALYLIVNYTGTATYFWMLCEGLYL-LMILIFTFNKGQFIVRFCIILGWGAPLVIIILFGSLRFSVGASNLCHLDGFNNLMYIMLVPIFVTIIFNMIFMAFILGILFNKFRNHRNIEQHQGQKAAKAILILTPVMGLHSLLLLVQPDDAMWLKVHKYASALTNSLQGFLITMPFCFFNSEIHEAIKMRRRRLQF 1208
            C   +DG LCW+ T AG+T EQ+CP  + DF+ S +  K C  +G W      N+++T+Y  C    +          Y+  +G+ +S+++L ISLA+ F+FK L+C RITLHKN+FF  ++NS   ++++  ++  +N   V    + C+    I  Y     YFWMLCEG+YL  +I++  F + Q ++ +  +LGWG PL+   +    R S   ++ C +    +L+YI+  PI   ++ N+ F+  I+ +L  K +     E     KA +A LIL P++G+  +LL  +P   +  +++ Y   +    QG L+   FCFFN E+     +RR   Q+
Sbjct:   77 CNRTWDGWLCWDDTAAGVTSEQHCPDYFQDFDPSEMVTKICTENGHWFLHPESNRTWTNYTRCNEHTNEGRMTAMNLFYLALIGHGLSLVSLFISLAIFFHFKSLSCQRITLHKNLFFSFVLNSVITIIWLTAVA--NNQELVQRNPTSCKVSMFIHLYLFGCNYFWMLCEGIYLHTLIVVAVFAEKQHLMWY-YLLGWGFPLIPASIHAIAR-SYYYNDNCWISSKTSLLYIIHGPICAALVVNVFFLLNIVRVLITKLKVTHQAESSLYMKAVRATLILVPLLGIQYVLLPYKPGGRVSSEIYDYIMHILMHYQGLLVATIFCFFNGEVQAV--LRRHWNQY 414          
BLAST of Calcitonin family peptide receptor vs. Ensembl Medaka
Match: calcr (calcitonin receptor [Source:NCBI gene;Acc:101174680])

HSP 1 Score: 169.474 bits (428), Expect = 5.184e-47
Identity = 115/381 (30.18%), Postives = 199/381 (52.23%), Query Frame = 3
Query:  186 PPPTDGQLYCRAIYDGLLCWNYTKAGLTVEQNCPALYD-FNVSALAYKSCLPSGEWLTKGGVNQSYTDYMACVP------KASYSI-YIYFVGYSMSIIALVISLAVLFYFKQLNCHRITLHKNMFFCNLMNSTGWLLYINVLSMHSNDSAVYSM---CQALYLIVNYTGTATYFWMLCEGLYL-LMILIFTFNKGQFIVRFCIILGWGAPLVIIILFGSLRFSVGASNLCHLDGFNNLMYIMLVPIFVTIIFNMIFMAFILGILFNKFRNHRNIEQHQGQKAAKAILILTPVMGLHSLLLLVQPDDAMWLKVHKYASALTNSLQGFLITMPFCFFNSEIHEAIKMRRRRLQFTNKARLSNSRSKNIPRVRTPQTSLALGK 1292
            PP      +C   +DG LCW  T AG    QNCP  +D F+ +  A K C   G+W      N+++++Y  C        K++Y + Y+  VG+++SI +L+ISLA+ FYF+ L+C RITLHKN+FF  ++NS   ++Y+  +++ +N   V      C+ L+    Y     YFWMLCEG+YL  +I++  F + Q +  +  +LGWG PLV + +    R      N C +    +L+Y +  PI   ++ N+ F+  I+ +L  K R+    E +   KA +A LIL P++G+  ++   +P++ +  +V++Y   +    Q  +      F N ++  A+K  R+ +Q+  K +    R  +     T  T+ ++ +
Sbjct:   49 PPYNKSGPFCSRNWDGWLCWEDTPAGTFAAQNCPNYFDDFDPTEKATKYCGEDGQWFRHPDTNRTWSNYTLCNENTKAKLKSAYILFYMAIVGHALSIASLLISLAIFFYFRSLSCQRITLHKNLFFSYVLNSALTIIYL--VTVVNNPEVVARNPVGCKVLHFFHMYMLGCNYFWMLCEGIYLHTLIVVAVFAEEQHL-HWYYLLGWGFPLVPVSIHAVARKKYFDDN-CWMSVETHLLYAVHGPIVAALLVNLFFLLNIIRVLVTKLRDTHRAESNMYMKAVRATLILVPLLGIQFVIFPWRPENRLAGEVYEYVMHILMHYQVIIY-----FVNQKVQGALK--RQWMQY--KTQWGQRRKDHCSMRSTSYTATSITE 416          
BLAST of Calcitonin family peptide receptor vs. Planmine SMEST
Match: SMESG000066855.1 (SMESG000066855.1)

HSP 1 Score: 466.848 bits (1200), Expect = 1.625e-165
Identity = 221/229 (96.51%), Postives = 226/229 (98.69%), Query Frame = 3
Query:  114 MSFQNDSFDYLELERTSCEAQMPPPPPTDGQLYCRAIYDGLLCWNYTKAGLTVEQNCPALYDFNVSALAYKSCLPSGEWLTKGGVNQSYTDYMACVPKASYSIYIYFVGYSMSIIALVISLAVLFYFKQLNCHRITLHKNMFFCNLMNSTGWLLYINVLSMHSNDSAVYSMCQALYLIVNYTGTATYFWMLCEGLYLLMILIFTFNKGQFIVRFCIILGWGAPLVIIIL 800
            MSFQNDSFDYLELERTSCEAQMPPPPPTDGQLYCRAIYDGLLCWNYTKAGLTVEQNCPALYDFNVSALAYKSCLPSGEWLTKGGVNQSYTDYMACVPKASYSIYIYFVGYSMSIIALVISLAVLFYFKQLNCHRITLHKNMFFCNLMNSTGWLLYINVLSMHSNDSAVYSMCQALYLIVNYTGTATYFWMLCEGLYLLMILIFTFNKGQFIVRFCIILGWG   +++++
Sbjct:    1 MSFQNDSFDYLELERTSCEAQMPPPPPTDGQLYCRAIYDGLLCWNYTKAGLTVEQNCPALYDFNVSALAYKSCLPSGEWLTKGGVNQSYTDYMACVPKASYSIYIYFVGYSMSIIALVISLAVLFYFKQLNCHRITLHKNMFFCNLMNSTGWLLYINVLSMHSNDSAVYSMCQALYLIVNYTGTATYFWMLCEGLYLLMILIFTFNKGQFIVRFCIILGWGEFSILLLV 229          
BLAST of Calcitonin family peptide receptor vs. Planmine SMEST
Match: SMESG000066855.1 (SMESG000066855.1)

HSP 1 Score: 445.662 bits (1145), Expect = 1.613e-156
Identity = 211/211 (100.00%), Postives = 211/211 (100.00%), Query Frame = 3
Query:  114 MSFQNDSFDYLELERTSCEAQMPPPPPTDGQLYCRAIYDGLLCWNYTKAGLTVEQNCPALYDFNVSALAYKSCLPSGEWLTKGGVNQSYTDYMACVPKASYSIYIYFVGYSMSIIALVISLAVLFYFKQLNCHRITLHKNMFFCNLMNSTGWLLYINVLSMHSNDSAVYSMCQALYLIVNYTGTATYFWMLCEGLYLLMILIFTFNKGQFI 746
            MSFQNDSFDYLELERTSCEAQMPPPPPTDGQLYCRAIYDGLLCWNYTKAGLTVEQNCPALYDFNVSALAYKSCLPSGEWLTKGGVNQSYTDYMACVPKASYSIYIYFVGYSMSIIALVISLAVLFYFKQLNCHRITLHKNMFFCNLMNSTGWLLYINVLSMHSNDSAVYSMCQALYLIVNYTGTATYFWMLCEGLYLLMILIFTFNKGQFI
Sbjct:    1 MSFQNDSFDYLELERTSCEAQMPPPPPTDGQLYCRAIYDGLLCWNYTKAGLTVEQNCPALYDFNVSALAYKSCLPSGEWLTKGGVNQSYTDYMACVPKASYSIYIYFVGYSMSIIALVISLAVLFYFKQLNCHRITLHKNMFFCNLMNSTGWLLYINVLSMHSNDSAVYSMCQALYLIVNYTGTATYFWMLCEGLYLLMILIFTFNKGQFI 211          

HSP 2 Score: 127.487 bits (319), Expect = 2.265e-33
Identity = 60/60 (100.00%), Postives = 60/60 (100.00%), Query Frame = 3
Query: 1125 GFLITMPFCFFNSEIHEAIKMRRRRLQFTNKARLSNSRSKNIPRVRTPQTSLALGKSYEI 1304
            GFLITMPFCFFNSEIHEAIKMRRRRLQFTNKARLSNSRSKNIPRVRTPQTSLALGKSYEI
Sbjct:  212 GFLITMPFCFFNSEIHEAIKMRRRRLQFTNKARLSNSRSKNIPRVRTPQTSLALGKSYEI 271          
BLAST of Calcitonin family peptide receptor vs. Planmine SMEST
Match: SMESG000066855.1 (SMESG000066855.1)

HSP 1 Score: 445.277 bits (1144), Expect = 6.323e-156
Identity = 211/213 (99.06%), Postives = 213/213 (100.00%), Query Frame = 3
Query:  114 MSFQNDSFDYLELERTSCEAQMPPPPPTDGQLYCRAIYDGLLCWNYTKAGLTVEQNCPALYDFNVSALAYKSCLPSGEWLTKGGVNQSYTDYMACVPKASYSIYIYFVGYSMSIIALVISLAVLFYFKQLNCHRITLHKNMFFCNLMNSTGWLLYINVLSMHSNDSAVYSMCQALYLIVNYTGTATYFWMLCEGLYLLMILIFTFNKGQFIVR 752
            MSFQNDSFDYLELERTSCEAQMPPPPPTDGQLYCRAIYDGLLCWNYTKAGLTVEQNCPALYDFNVSALAYKSCLPSGEWLTKGGVNQSYTDYMACVPKASYSIYIYFVGYSMSIIALVISLAVLFYFKQLNCHRITLHKNMFFCNLMNSTGWLLYINVLSMHSNDSAVYSMCQALYLIVNYTGTATYFWMLCEGLYLLMILIFTFNKGQFI++
Sbjct:    1 MSFQNDSFDYLELERTSCEAQMPPPPPTDGQLYCRAIYDGLLCWNYTKAGLTVEQNCPALYDFNVSALAYKSCLPSGEWLTKGGVNQSYTDYMACVPKASYSIYIYFVGYSMSIIALVISLAVLFYFKQLNCHRITLHKNMFFCNLMNSTGWLLYINVLSMHSNDSAVYSMCQALYLIVNYTGTATYFWMLCEGLYLLMILIFTFNKGQFILQ 213          
BLAST of Calcitonin family peptide receptor vs. Planmine SMEST
Match: SMESG000023013.1 (SMESG000023013.1)

HSP 1 Score: 241.506 bits (615), Expect = 5.692e-75
Identity = 132/354 (37.29%), Postives = 197/354 (55.65%), Query Frame = 3
Query:  189 PPTDGQLYCRAIYDGL-LCWNYTKAGLTVEQNCPALYDFNVSALAYKSCLPSGEWLTKGGVNQSYTDYMACV---PKASYSIYIYFVGYSMSIIALVISLAVLFYFKQLNCHRITLHKNMFFCNLMNSTGWLLYINVLSMHSNDSAVYSMCQALYLIVNYTGTATYFWMLCEGLYLLMILIFTFNKGQFIVRFCIILGWGAPLVIIILFGSLRFSVGASNLCHLDGFNNLMYIMLVPIFVTIIFNMIFMAFILGILFNKFRNHRNIEQHQGQKAAKAILILTPVMGLHSLLLLVQPDDAMWLKVHKYASALTNSLQGFLITMPFCFFNSEIHEAIKMRRRRLQFTNKARLSNSR 1238
            PP +G  YC A  D L  CWNYTKAG      CP L  FN +A A K C  +G W      N  +++Y  C+   P  S  +Y++F GYS+S++ L ISL + F FKQL C R+TLHKN+F C+L+N+  W+ +  V+S           CQ L++I  Y    TYFWM  EG+YL +ILI TF+KG  ++  CI+ GWG PL++  ++   R+ +     C  +  + +  I+ +P  V +  N++ + FIL  L  K  +  N E+ Q  K AKA+ IL P++GL +++  + PD+     +  Y++A+ +S QG L++   CFFN E+   I  RRR  Q +    L  +R
Sbjct:   15 PPMNGTSYCNATKDKLGTCWNYTKAGEIAFAPCPKLPGFNWNAEASKKCEINGTWYFSIEENNYWSNYSKCLQNKPNVSL-VYVFFAGYSLSVLCLSISLFIFFVFKQLRCDRVTLHKNLFMCHLINAIIWINFYVVISNGDVMQRNPIHCQILFVIATYFSVGTYFWMFSEGIYLAVILILTFHKGPILLTICIVTGWGLPLILTSIYVISRYLMEKPEKCWTEP-SKMYLILAIPNVVALGANLLILLFILKTLVTKLSHPTNREETQWSKTAKAVFILIPLLGLQNIIFFIYPDNQEVRLIQDYSTAVLSSFQGVLVSFILCFFNHEVRTII--RRRACQHSLLQPLKTTR 364          
BLAST of Calcitonin family peptide receptor vs. Planmine SMEST
Match: SMESG000006966.1 (SMESG000006966.1)

HSP 1 Score: 235.343 bits (599), Expect = 1.117e-72
Identity = 126/378 (33.33%), Postives = 213/378 (56.35%), Query Frame = 3
Query:  129 DSFDYLELERTSCEAQMPPPPPTDGQLYCRAIYDGL-LCWNYTKAGLTVEQNCPALYDFNVSALAYKSCLPSGEWLTKGGVNQSYTDYMACVPKASY--SIYIYFVGYSMSIIALVISLAVLFYFKQLNCHRITLHKNMFFCNLMNSTGWLLYINVLSMHSNDSAVYSMCQALYLIVNYTGTATYFWMLCEGLYLLMILIFTFNKG-QFIVRFCIILGWGAPLVIIILFGSLRFSVGASNLCHLDGFNNLMYIMLVPIFVTIIFNMIFMAFILGILFNKFRNHRNIEQHQGQKAAKAILILTPVMGLHSLLLLVQPDDAMWLKVHKYASALTNSLQGFLITMPFCFFNSEIHEAI---KMRRRRLQFTNKARLSNSRS 1241
            D+F+  +L + +C  Q   P P    ++C  I+D L LCWN+TK G    QNCP +  F+  A+A K C  +G W     +N+++T++  C+ K     ++YIYF GYS+S++ + ISL + FYFK+L C R+ +HKN+F   ++N+  W+ ++ ++S  +      S CQ +Y+IV +   ++YFW   EGLYL  +L+  F  G + ++  C+  GWG PL++ I + SLR+ +     C     + +  I+++P  + +I N++ +  IL IL  K  +  N EQ Q +K A+AI IL PV+G+ ++L  +  +D     + ++ +A+  S QG +++   CF N+E+  AI       RR Q     R ++ RS
Sbjct:    2 DNFEREKL-KNACLMQ---PIPNKVDIFCPPIFDDLYLCWNFTKGGSKTYQNCPDIPGFSKEAMASKKCEINGTWYIDQALNRTWTNFDPCINKVPNINAVYIYFAGYSLSVLCMAISLFIFFYFKKLQCERVFIHKNLFISYVLNAITWMTFLAIISKPTVMVHNPSYCQIIYVIVTFFNVSSYFWTFSEGLYLATVLVMAFQDGSKKLLYLCVFFGWGFPLILTIFYASLRYQLEQPEKCWTMK-SKMQNILIIPNIIALIANLVIVIVILKILLTKLWHPVNREQKQWRKTARAIFILFPVLGIQNILFFMSSEDRNVSLIQEFIAAVIISFQGTVMSFILCFCNNEVKVAILHNTAATRRFQ---TVRSTSRRS 371          
The following BLAST results are available for this feature:
BLAST of Calcitonin family peptide receptor vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
CALCR2.234e-5431.65calcitonin receptor [Source:HGNC Symbol;Acc:HGNC:1... [more]
CALCR2.234e-5431.65calcitonin receptor [Source:HGNC Symbol;Acc:HGNC:1... [more]
CALCR1.101e-5030.36calcitonin receptor [Source:HGNC Symbol;Acc:HGNC:1... [more]
CALCR1.238e-5030.36calcitonin receptor [Source:HGNC Symbol;Acc:HGNC:1... [more]
CALCRL3.380e-5031.03calcitonin receptor like receptor [Source:HGNC Sym... [more]
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BLAST of Calcitonin family peptide receptor vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
pdfr-12.877e-3224.04Calcitonin receptor-like protein 1 [Source:UniPro... [more]
pdfr-12.877e-3224.04Calcitonin receptor-like protein 1 [Source:UniPro... [more]
pdfr-14.737e-3224.04Calcitonin receptor-like protein 1 [Source:UniPro... [more]
pdfr-14.737e-3224.04Calcitonin receptor-like protein 1 [Source:UniPro... [more]
pdfr-14.767e-3223.77Calcitonin receptor-like protein 1 [Source:UniPro... [more]
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BLAST of Calcitonin family peptide receptor vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
hec4.003e-4231.99gene:FBgn0030437 transcript:FBtr0343652[more]
hec4.003e-4231.99gene:FBgn0030437 transcript:FBtr0073753[more]
Dh31-R5.223e-4129.43gene:FBgn0052843 transcript:FBtr0087755[more]
Dh31-R1.881e-4029.22gene:FBgn0052843 transcript:FBtr0330735[more]
Dh44-R24.680e-4027.65gene:FBgn0033744 transcript:FBtr0087936[more]
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BLAST of Calcitonin family peptide receptor vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
calcr5.294e-5431.40calcitonin receptor [Source:ZFIN;Acc:ZDB-GENE-0605... [more]
calcr5.294e-5431.40calcitonin receptor [Source:ZFIN;Acc:ZDB-GENE-0605... [more]
calcr7.551e-5431.40calcitonin receptor [Source:ZFIN;Acc:ZDB-GENE-0605... [more]
calcr7.551e-5431.40calcitonin receptor [Source:ZFIN;Acc:ZDB-GENE-0605... [more]
calcr2.459e-5331.32calcitonin receptor [Source:ZFIN;Acc:ZDB-GENE-0605... [more]
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BLAST of Calcitonin family peptide receptor vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
calcrl2.000e-5030.49calcitonin receptor like receptor [Source:NCBI gen... [more]
calcrl2.490e-4332.50calcitonin receptor like receptor [Source:NCBI gen... [more]
calcrl4.278e-4332.50calcitonin receptor like receptor [Source:NCBI gen... [more]
calcrl3.257e-4132.52calcitonin receptor like receptor [Source:NCBI gen... [more]
yif1b7.833e-4028.07Yip1 interacting factor homolog B, membrane traffi... [more]
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BLAST of Calcitonin family peptide receptor vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Calcr2.185e-5430.13calcitonin receptor [Source:MGI Symbol;Acc:MGI:101... [more]
Calcr2.185e-5430.13calcitonin receptor [Source:MGI Symbol;Acc:MGI:101... [more]
Calcr2.185e-5430.13calcitonin receptor [Source:MGI Symbol;Acc:MGI:101... [more]
Calcr1.780e-5127.49calcitonin receptor [Source:MGI Symbol;Acc:MGI:101... [more]
Calcr1.780e-5127.49calcitonin receptor [Source:MGI Symbol;Acc:MGI:101... [more]
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BLAST of Calcitonin family peptide receptor vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|O08893|CALCR_CAVPO3.487e-5530.10Calcitonin receptor OS=Cavia porcellus OX=10141 GN... [more]
sp|P79222|CALCR_RABIT4.627e-5432.32Calcitonin receptor OS=Oryctolagus cuniculus OX=99... [more]
sp|P30988|CALCR_HUMAN1.008e-5331.65Calcitonin receptor OS=Homo sapiens OX=9606 GN=CAL... [more]
sp|Q7ZXS8|CALRL_XENLA8.600e-5232.61Calcitonin gene-related peptide type 1 receptor OS... [more]
sp|Q68EK2|CALRL_DANRE2.946e-5130.70Calcitonin gene-related peptide type 1 receptor OS... [more]
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BLAST of Calcitonin family peptide receptor vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A0K0PVL89.347e-7437.25DH31-like receptor 1 OS=Platynereis dumerilii OX=6... [more]
R7T7Q88.662e-6834.47Uncharacterized protein OS=Capitella teleta OX=283... [more]
V4B1K45.034e-6532.81Uncharacterized protein OS=Lottia gigantea OX=2251... [more]
A0A1S3K8Z33.619e-6334.57calcitonin gene-related peptide type 1 receptor is... [more]
A0A1S3K7X25.125e-6334.57calcitonin gene-related peptide type 1 receptor is... [more]
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BLAST of Calcitonin family peptide receptor vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
calcr1.863e-5332.31calcitonin receptor [Source:ZFIN;Acc:ZDB-GENE-0605... [more]
ENSAMXT00000051776.12.800e-5230.97pep primary_assembly:Astyanax_mexicanus-2.0:13:448... [more]
ENSAMXT00000037591.11.497e-4028.53corticotropin releasing hormone receptor 1 [Source... [more]
pth2ra8.401e-4026.98parathyroid hormone 2 receptor [Source:NCBI gene;A... [more]
pth2ra9.006e-4026.98parathyroid hormone 2 receptor [Source:NCBI gene;A... [more]
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BLAST of Calcitonin family peptide receptor vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSPMAT00000000542.11.251e-4831.12pep scaffold:Pmarinus_7.0:GL476735:164228:192153:1... [more]
pth1r3.976e-4427.43parathyroid hormone 1 receptor [Source:ZFIN;Acc:ZD... [more]
ENSPMAT00000004899.18.022e-3624.66pep scaffold:Pmarinus_7.0:GL476767:721819:758871:-... [more]
ENSPMAT00000009958.11.991e-3024.04pep scaffold:Pmarinus_7.0:GL477206:37870:64312:-1 ... [more]
ENSPMAT00000004243.17.885e-2623.89pep scaffold:Pmarinus_7.0:GL484465:15708:23345:-1 ... [more]
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BLAST of Calcitonin family peptide receptor vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Calcitonin family peptide receptor vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO345374.072e-1925.00Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO428009.359e-1625.64Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO324671.447e-1527.03Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO391961.539e-1524.61Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO291671.940e-1526.92Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Calcitonin family peptide receptor vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
calcr5.944e-5531.52calcitonin receptor [Source:NCBI gene;Acc:10117468... [more]
ENSORLT00000000113.24.484e-5433.43calcitonin gene-related peptide type 1 receptor [S... [more]
calcrla5.469e-5332.27calcitonin receptor like receptor [Source:NCBI gen... [more]
calcrla6.749e-5332.27calcitonin receptor like receptor [Source:NCBI gen... [more]
calcr5.184e-4730.18calcitonin receptor [Source:NCBI gene;Acc:10117468... [more]
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BLAST of Calcitonin family peptide receptor vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000066855.11.625e-16596.51SMESG000066855.1[more]
SMESG000066855.11.613e-156100.00SMESG000066855.1[more]
SMESG000066855.16.323e-15699.06SMESG000066855.1[more]
SMESG000023013.15.692e-7537.29SMESG000023013.1[more]
SMESG000006966.11.117e-7233.33SMESG000006966.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30018600 ID=SMED30018600|Name=Calcitonin family peptide receptor|organism=Schmidtea mediterranea sexual|type=transcript|length=1448bp
GCTAAGATCAATTTCATTTTTTCCAAAGGACTTTCACAAATTCTGCCGCA
ATTTGCGCTCATAGAAAAGGTTTTCACTTGACTCAAGTTCACCGAACTCG
GTCTCCATCATTTATGTCATTTCAAAATGATAGTTTCGACTACTTGGAAC
TGGAAAGAACAAGTTGTGAGGCCCAAATGCCGCCGCCGCCTCCAACAGAT
GGTCAGTTGTATTGTCGAGCGATTTACGATGGACTGCTGTGCTGGAATTA
TACAAAAGCCGGATTGACTGTCGAACAGAATTGTCCCGCACTTTACGATT
TCAACGTGTCAGCTTTGGCCTACAAATCGTGCCTACCTTCAGGAGAATGG
CTTACGAAGGGTGGAGTCAACCAGTCATATACAGATTACATGGCCTGCGT
TCCGAAAGCAAGCTACTCAATCTACATCTACTTTGTCGGCTACTCAATGT
CTATTATTGCGCTCGTGATCTCATTGGCTGTTCTCTTTTATTTTAAACAG
CTGAATTGTCACAGAATAACTTTGCACAAAAATATGTTTTTTTGTAACCT
GATGAACTCGACGGGGTGGCTCCTCTATATCAATGTGCTCTCGATGCATT
CAAACGATTCAGCTGTATACTCAATGTGCCAAGCACTTTATCTCATTGTC
AATTACACCGGAACTGCAACTTATTTTTGGATGCTTTGTGAAGGCTTATA
TTTGTTGATGATATTAATATTCACATTCAATAAAGGCCAATTCATAGTTC
GTTTTTGTATTATTCTGGGGTGGGGAGCTCCTCTAGTAATTATCATATTG
TTTGGATCTCTGAGATTTTCAGTGGGTGCCAGCAATCTATGTCATCTTGA
TGGCTTTAATAATCTCATGTACATAATGCTGGTTCCAATTTTCGTTACGA
TAATATTTAACATGATTTTTATGGCATTTATTCTTGGAATACTTTTCAAT
AAATTTCGAAATCACCGCAATATAGAACAGCACCAAGGACAAAAGGCGGC
GAAAGCGATTTTAATTCTGACTCCGGTGATGGGACTTCATTCATTGTTGT
TGCTAGTCCAGCCGGATGATGCTATGTGGCTCAAGGTTCACAAATATGCG
TCTGCGTTAACGAATTCATTACAGGGATTTCTCATAACGATGCCTTTCTG
CTTCTTCAATAGTGAAATTCATGAAGCCATAAAGATGCGACGCCGAAGAC
TTCAGTTCACCAACAAGGCTAGATTGTCTAACAGTCGCAGCAAAAATATT
CCTAGAGTCAGAACGCCTCAAACGTCTCTTGCGCTTGGAAAATCATATGA
AATATAAATAATTGTCATGAATAGTTTTTTATTTGAGAATAGACAGAGAC
TGCACAATAAGTGAGTGTTGAGGAGTACTTGGGACGTGGAATGTTACTTT
CAATAATCTGGAATTGCGAATTTATTATTTATAGTAAATAATAAATTT
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protein sequence of SMED30018600-orf-1

>SMED30018600-orf-1 ID=SMED30018600-orf-1|Name=SMED30018600-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=398bp
MSFQNDSFDYLELERTSCEAQMPPPPPTDGQLYCRAIYDGLLCWNYTKAG
LTVEQNCPALYDFNVSALAYKSCLPSGEWLTKGGVNQSYTDYMACVPKAS
YSIYIYFVGYSMSIIALVISLAVLFYFKQLNCHRITLHKNMFFCNLMNST
GWLLYINVLSMHSNDSAVYSMCQALYLIVNYTGTATYFWMLCEGLYLLMI
LIFTFNKGQFIVRFCIILGWGAPLVIIILFGSLRFSVGASNLCHLDGFNN
LMYIMLVPIFVTIIFNMIFMAFILGILFNKFRNHRNIEQHQGQKAAKAIL
ILTPVMGLHSLLLLVQPDDAMWLKVHKYASALTNSLQGFLITMPFCFFNS
EIHEAIKMRRRRLQFTNKARLSNSRSKNIPRVRTPQTSLALGKSYEI*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000099neuron
PLANA:0000101muscle cell
PLANA:0000418head
Vocabulary: INTERPRO
TermDefinition
IPR036445GPCR_2_extracell_dom_sf
IPR001879GPCR_2_extracellular_dom
IPR017983GPCR_2_secretin-like_CS
IPR017981GPCR_2-like
IPR000832GPCR_2_secretin-like
Vocabulary: molecular function
TermDefinition
GO:0004930G-protein coupled receptor activity
GO:0004888transmembrane signaling receptor activity
GO:0004871signal transducer activity
GO:0004948calcitonin receptor activity
Vocabulary: cellular component
TermDefinition
GO:0016021integral component of membrane
GO:0016020membrane
GO:0005886plasma membrane
Vocabulary: biological process
TermDefinition
GO:0007186G-protein coupled receptor signaling pathway
GO:0007166cell surface receptor signaling pathway
GO:0007165signal transduction
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000832GPCR, family 2, secretin-likePRINTSPR00249GPCRSECRETINcoord: 253..278
score: 30.25
coord: 212..237
score: 26.4
coord: 136..160
score: 20.0
coord: 104..128
score: 36.54
coord: 174..197
score: 40.54
coord: 295..315
score: 33.74
coord: 327..348
score: 29.89
IPR000832GPCR, family 2, secretin-likePFAMPF000027tm_2coord: 104..341
e-value: 7.1E-48
score: 163.0
IPR001879GPCR, family 2, extracellular hormone receptor domainSMARTSM00008HormR_1coord: 30..104
e-value: 2.6E-11
score: 53.6
IPR001879GPCR, family 2, extracellular hormone receptor domainPFAMPF02793HRMcoord: 32..96
e-value: 6.4E-12
score: 45.6
IPR001879GPCR, family 2, extracellular hormone receptor domainPROSITEPS50227G_PROTEIN_RECEP_F2_3coord: 17..99
score: 15.709
IPR036445GPCR family 2, extracellular hormone receptor domain superfamilyGENE3DG3DSA:4.10.1240.10coord: 3..99
e-value: 2.2E-21
score: 78.1
IPR036445GPCR family 2, extracellular hormone receptor domain superfamilySUPERFAMILYSSF111418Hormone receptor domaincoord: 10..110
NoneNo IPR availableGENE3DG3DSA:1.20.1070.10coord: 100..382
e-value: 3.3E-58
score: 199.0
NoneNo IPR availablePANTHERPTHR45620:SF31DIURETIC HORMONE 31 RECEPTOR, ISOFORM Ccoord: 14..389
NoneNo IPR availablePANTHERPTHR45620FAMILY NOT NAMEDcoord: 14..389
NoneNo IPR availableCDDcd152607tmB1_NPR_B4_insect-likecoord: 103..362
e-value: 4.72391E-68
score: 214.444
NoneNo IPR availableSUPERFAMILYSSF81321Family A G protein-coupled receptor-likecoord: 95..375
NoneNo IPR availableTMHMMTMhelixcoord: 298..315
NoneNo IPR availableTMHMMTMhelixcoord: 210..232
NoneNo IPR availableTMHMMTMhelixcoord: 142..161
NoneNo IPR availableTMHMMTMhelixcoord: 330..352
NoneNo IPR availableTMHMMTMhelixcoord: 103..125
NoneNo IPR availableTMHMMTMhelixcoord: 256..278
NoneNo IPR availableTMHMMTMhelixcoord: 181..203
IPR017983GPCR, family 2, secretin-like, conserved sitePROSITEPS00649G_PROTEIN_RECEP_F2_1coord: 34..58
IPR017981GPCR, family 2-likePROSITEPS50261G_PROTEIN_RECEP_F2_4coord: 102..349
score: 32.625