Synaptotagmin 1

Overview


Name	Synaptotagmin 1
Smed ID	SMED30018598
Length (bp)	1426

Neoblast Clusters

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30018598

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 2

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication	Specimen	Lifecycle	Evidence
tail region	SMED30018598	SMESG000059797.1	SmedASXL_010374	SmedAsxl_ww_GCZZ01	PMID:27034770 Currie et al., 2016
parenchyma	SMED30018598	SMESG000059797.1	dd_Smed_v4_13680_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018

Note: Hover over icons to view figure legend

Homology

[Close]

BLAST of Synaptotagmin 1 vs. Ensembl Human
Match: SYT1 (synaptotagmin 1 [Source:HGNC Symbol;Acc:HGNC:11509])

HSP 1 Score: 195.282 bits (495), Expect = 1.013e-56
Identity = 116/271 (42.80%), Postives = 163/271 (60.15%), Query Frame = 1

Query:  289 LGKLVYAIKYFPESESLRVTVKSGHDLIKLNTGGTSDPYVKVWLKEKPKLKFETKIKRRTRNPVFNEDFTFTVSPEELPTQTLIFFFYDFDRFSKHEQIGCLMLDLGALDLSKLIEDWAELDQPSSDVNTEIPLGEICMSLKQDPDEEKLFVTILEAKGLRKHDEEDLYDPFLRLSLEEXXXXXXXXXXXXXXXXXPNPYYNEDFEFQLSAELSTKVQLVVTAFNCSNNNIKHSMPIGNIVLGPTITGSGYKHWKEIISNSKRTIVRWHGL 1101
            LGKL Y++ Y  ++  L V +    +L  L+ GGTSDPYVKV+L    K KFETK+ R+T NPVFNE FTF V   EL  +TL+   YDFDRFSKH+ IG   + +  +D   + E+W +L   S++   +  LG+IC SL+  P   KL V ILEAK L+K D   L DP++++ L + G  + KKK T  K    NPYYNE F F++  E   KVQ+VVT  +   + I  +  IG + +G   TG+  +HW ++++N +R I +WH L
Sbjct:  143 LGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVTEEWRDLQ--SAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTL-NPYYNESFSFEVPFEQIQKVQVVVTVLDY--DKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTL 408

HSP 2 Score: 63.1586 bits (152), Expect = 4.513e-10
Identity = 36/113 (31.86%), Postives = 63/113 (55.75%), Query Frame = 1

Query:  259 LKALEKP-KESLGKLVYAIKYFPESESLRVTVKSGHDLIKLNTGGTSDPYVKVWLKEKPKLKFETKIKRRTR--NPVFNEDFTFTVSPEELPTQTLIFFFYDFDRFSKHEQIG 588
            L++ EK  +E LG + ++++Y P +  L V +    +L K++ GG SDPYVK+ L +  K   + K   +    NP +NE F+F V  E++    ++    D+D+  K++ IG
Sbjct:  263 LQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIG 375

[Close]

Query:  289 LGKLVYAIKYFPESESLRVTVKSGHDLIKLNTGGTSDPYVKVWLKEKPKLKFETKIKRRTRNPVFNEDFTFTVSPEELPTQTLIFFFYDFDRFSKHEQIGCLMLDLGALDLSKLIEDWAELDQPSSDVNTEIPLGEICMSLKQDPDEEKLFVTILEAKGLRKHDEEDLYDPFLRLSLEEXXXXXXXXXXXXXXXXXPNPYYNEDFEFQLSAELSTKVQLVVTAFNCSNNNIKHSMPIGNIVLGPTITGSGYKHWKEIISNSKRTIVRWHGL 1101
            LGKL Y++ Y  ++  L V +    +L  L+ GGTSDPYVKV+L    K KFETK+ R+T NPVFNE FTF V   EL  +TL+   YDFDRFSKH+ IG   + +  +D   + E+W +L   S++   +  LG+IC SL+  P   KL V ILEAK L+K D   L DP++++ L + G  + KKK T  K    NPYYNE F F++  E   KVQ+VVT  +   + I  +  IG + +G   TG+  +HW ++++N +R I +WH L
Sbjct:  143 LGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVTEEWRDLQ--SAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTL-NPYYNESFSFEVPFEQIQKVQVVVTVLDY--DKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTL 408

HSP 2 Score: 63.1586 bits (152), Expect = 4.513e-10
Identity = 36/113 (31.86%), Postives = 63/113 (55.75%), Query Frame = 1

Query:  259 LKALEKP-KESLGKLVYAIKYFPESESLRVTVKSGHDLIKLNTGGTSDPYVKVWLKEKPKLKFETKIKRRTR--NPVFNEDFTFTVSPEELPTQTLIFFFYDFDRFSKHEQIG 588
            L++ EK  +E LG + ++++Y P +  L V +    +L K++ GG SDPYVK+ L +  K   + K   +    NP +NE F+F V  E++    ++    D+D+  K++ IG
Sbjct:  263 LQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIG 375

[Close]

Query:  289 LGKLVYAIKYFPESESLRVTVKSGHDLIKLNTGGTSDPYVKVWLKEKPKLKFETKIKRRTRNPVFNEDFTFTVSPEELPTQTLIFFFYDFDRFSKHEQIGCLMLDLGALDLSKLIEDWAELDQPSSDVNTEIPLGEICMSLKQDPDEEKLFVTILEAKGLRKHDEEDLYDPFLRLSLEEXXXXXXXXXXXXXXXXXPNPYYNEDFEFQLSAELSTKVQLVVTAFNCSNNNIKHSMPIGNIVLGPTITGSGYKHWKEIISNSKRTIVRWHGL 1101
            LGKL Y++ Y  ++  L V +    +L  L+ GGTSDPYVKV+L    K KFETK+ R+T NPVFNE FTF V   EL  +TL+   YDFDRFSKH+ IG   + +  +D   + E+W +L   S++   +  LG+IC SL+  P   KL V ILEAK L+K D   L DP++++ L + G  + KKK T  K    NPYYNE F F++  E   KVQ+VVT  +   + I  +  IG + +G   TG+  +HW ++++N +R I +WH L
Sbjct:  143 LGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVTEEWRDLQ--SAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTL-NPYYNESFSFEVPFEQIQKVQVVVTVLDY--DKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTL 408

HSP 2 Score: 63.1586 bits (152), Expect = 4.513e-10
Identity = 36/113 (31.86%), Postives = 63/113 (55.75%), Query Frame = 1

Query:  259 LKALEKP-KESLGKLVYAIKYFPESESLRVTVKSGHDLIKLNTGGTSDPYVKVWLKEKPKLKFETKIKRRTR--NPVFNEDFTFTVSPEELPTQTLIFFFYDFDRFSKHEQIG 588
            L++ EK  +E LG + ++++Y P +  L V +    +L K++ GG SDPYVK+ L +  K   + K   +    NP +NE F+F V  E++    ++    D+D+  K++ IG
Sbjct:  263 LQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIG 375

[Close]

BLAST of Synaptotagmin 1 vs. Ensembl Human
Match: SYT1 (synaptotagmin 1 [Source:HGNC Symbol;Acc:HGNC:11509])

HSP 1 Score: 194.897 bits (494), Expect = 1.404e-56
Identity = 116/271 (42.80%), Postives = 163/271 (60.15%), Query Frame = 1

Query:  289 LGKLVYAIKYFPESESLRVTVKSGHDLIKLNTGGTSDPYVKVWLKEKPKLKFETKIKRRTRNPVFNEDFTFTVSPEELPTQTLIFFFYDFDRFSKHEQIGCLMLDLGALDLSKLIEDWAELDQPSSDVNTEIPLGEICMSLKQDPDEEKLFVTILEAKGLRKHDEEDLYDPFLRLSLEEXXXXXXXXXXXXXXXXXPNPYYNEDFEFQLSAELSTKVQLVVTAFNCSNNNIKHSMPIGNIVLGPTITGSGYKHWKEIISNSKRTIVRWHGL 1101
            LGKL Y++ Y  ++  L V +    +L  L+ GGTSDPYVKV+L    K KFETK+ R+T NPVFNE FTF V   EL  +TL+   YDFDRFSKH+ IG   + +  +D   + E+W +L   S++   +  LG+IC SL+  P   KL V ILEAK L+K D   L DP++++ L + G  + KKK T  K    NPYYNE F F++  E   KVQ+VVT  +   + I  +  IG + +G   TG+  +HW ++++N +R I +WH L
Sbjct:  140 LGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVTEEWRDLQ--SAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTL-NPYYNESFSFEVPFEQIQKVQVVVTVLDY--DKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTL 405

HSP 2 Score: 62.7734 bits (151), Expect = 5.063e-10
Identity = 36/113 (31.86%), Postives = 63/113 (55.75%), Query Frame = 1

Query:  259 LKALEKP-KESLGKLVYAIKYFPESESLRVTVKSGHDLIKLNTGGTSDPYVKVWLKEKPKLKFETKIKRRTR--NPVFNEDFTFTVSPEELPTQTLIFFFYDFDRFSKHEQIG 588
            L++ EK  +E LG + ++++Y P +  L V +    +L K++ GG SDPYVK+ L +  K   + K   +    NP +NE F+F V  E++    ++    D+D+  K++ IG
Sbjct:  260 LQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIG 372

[Close]

BLAST of Synaptotagmin 1 vs. Ensembl Human
Match: SYT2 (synaptotagmin 2 [Source:HGNC Symbol;Acc:HGNC:11510])

HSP 1 Score: 193.741 bits (491), Expect = 4.445e-56
Identity = 115/272 (42.28%), Postives = 166/272 (61.03%), Query Frame = 1

Query:  286 SLGKLVYAIKYFPESESLRVTVKSGHDLIKLNTGGTSDPYVKVWLKEKPKLKFETKIKRRTRNPVFNEDFTFTVSPEELPTQTLIFFFYDFDRFSKHEQIGCLMLDLGALDLSKLIEDWAELDQPSSDVNTEIPLGEICMSLKQDPDEEKLFVTILEAKGLRKHDEEDLYDPFLRLSLEEXXXXXXXXXXXXXXXXXPNPYYNEDFEFQLSAELSTKVQLVVTAFNCSNNNIKHSMPIGNIVLGPTITGSGYKHWKEIISNSKRTIVRWHGL 1101
            +LGKL +++ Y  ++  L V V    +L  L+ GGTSDPYVKV+L    K K+ETK+ R+T NP FNE FTF V  +EL  +TL+   YDFDRFSKH+ IG + + +  +DL + IE+W +L     +   +  LG+IC SL+  P   KL V ILEAK L+K D   L DP++++ L + G  + KKK T  KK   NPY+NE F F++  E   KVQ+VVT  +   + +  +  IG I +G   TG+  +HW ++++N +R I +WH L
Sbjct:  139 NLGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVKVFLLPDKKKKYETKVHRKTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVPMNTVDLGQPIEEWRDLQGGEKEEPEK--LGDICTSLRYVPTAGKLTVCILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTVKKKTL-NPYFNESFSFEIPFEQIQKVQVVVTVLDY--DKLGKNEAIGKIFVGSNATGTELRHWSDMLANPRRPIAQWHSL 405

[Close]

BLAST of Synaptotagmin 1 vs. Ensembl Celegans
Match: snt-1 (Synaptotagmin-1 [Source:UniProtKB/Swiss-Prot;Acc:P34693])

HSP 1 Score: 193.741 bits (491), Expect = 2.665e-56
Identity = 115/271 (42.44%), Postives = 167/271 (61.62%), Query Frame = 1

Query:  289 LGKLVYAIKYFPESESLRVTVKSGHDLIKLNTGGTSDPYVKVWLKEKPKLKFETKIKRRTRNPVFNEDFTFTVSPEELPTQTLIFFFYDFDRFSKHEQIGCLMLDLGALDLSKLIEDWAELDQPSSDVNTEIPLGEICMSLKQDPDEEKLFVTILEAKGLRKHDEEDLYDPFLRLSLEEXXXXXXXXXXXXXXXXXPNPYYNEDFEFQLSAELSTKVQLVVTAFNCSNNNIKHSMPIGNIVLGPTITGSGYKHWKEIISNSKRTIVRWHGL 1101
            LG++ Y + Y  +   L VTV    DL  ++  GTSDPYVK++L  + K K ETK+ R+T NPVFNE F F V+  E+  +TL+F  YDFDRFSKH+QIG +++ LG +DL  +IE+W ++  P  D   E  LG+IC SL+  P   KL V ILEAK L+K D   L DP++++ L +GG  + KKK +  K    NPYYNE F F++  E   KV L++T  +   + +  +  IG  +LG   TG+  +HW +++++ +R I +WH L
Sbjct:  160 LGRIQYKLDYDFQQGQLTVTVIQAEDLPGMDMSGTSDPYVKLYLLPEKKKKVETKVHRKTLNPVFNETFIFKVAFNEITAKTLVFAIYDFDRFSKHDQIGQVLIPLGKIDLGAVIEEWKDIAPPPDDKEAEKSLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIVLMQGGKRLKKKKTSIKKCTL-NPYYNESFSFEVPFEQIQKVSLMITVMD--YDKLGSNDAIGRCLLGCNGTGAELRHWMDMLASPRRPIAQWHTL 427

[Close]

BLAST of Synaptotagmin 1 vs. Ensembl Celegans
Match: snt-1 (Synaptotagmin-1 [Source:UniProtKB/Swiss-Prot;Acc:P34693])

HSP 1 Score: 187.963 bits (476), Expect = 3.313e-54
Identity = 115/272 (42.28%), Postives = 166/272 (61.03%), Query Frame = 1

Query:  289 LGKLVYAIKYFPESESLRVTVKSGHDLIKLNTGGTSDPYVKVWLKEKPKLKFETKIKRRTRNPVFNEDFTFTVSPEELPTQTLIFFFYDFDRFSKHEQIGCLMLDLGALDLSKLIEDWAELDQPSSDVNTEIPLGEICMSLKQDPDEEKLFVTILEAKGLRKHDEEDLYDPFLRLSLEEXXXXXXXXXXXXXXXXXPNPYYNEDFEF-QLSAELSTKVQLVVTAFNCSNNNIKHSMPIGNIVLGPTITGSGYKHWKEIISNSKRTIVRWHGL 1101
            LG++ Y + Y  +   L VTV    DL  ++  GTSDPYVK++L  + K K ETK+ R+T NPVFNE F F V+  E+  +TL+F  YDFDRFSKH+QIG +++ LG +DL  +IE+W ++  P  D   E  LG+IC SL+  P   KL V ILEAK L+K D   L DP+++L +       +KKK T IK+ T NPY+NE F F +L      KV L++T  +   + +  +  IG  +LG   TG+  +HW +++++ +R I +WH L
Sbjct:  160 LGRIQYKLDYDFQQGQLTVTVIQAEDLPGMDMSGTSDPYVKLYLLPEKKKKVETKVHRKTLNPVFNETFIFKVAFNEITAKTLVFAIYDFDRFSKHDQIGQVLIPLGKIDLGAVIEEWKDIAPPPDDKEAEKSLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKLEMFGEDRKRLKKKKTNIKRKTLNPYFNESFVFDKLPLHKMKKVSLMITVMDY--DKLGSNDAIGRCLLGCNGTGAELRHWMDMLASPRRPIAQWHTL 429

[Close]

BLAST of Synaptotagmin 1 vs. Ensembl Celegans
Match: snt-3 (SyNapTotagmin [Source:UniProtKB/TrEMBL;Acc:Q965S5])

HSP 1 Score: 183.341 bits (464), Expect = 4.355e-54
Identity = 104/277 (37.55%), Postives = 163/277 (58.84%), Query Frame = 1

Query:  289 LGKLVYAIKYFPESESLRVTVKSGHDLIKLNTGGTSDPYVKVWLKEKPKLKFETKIKRRTRNPVFNEDFTFTVSPEELPTQTLIFFFYDFDRFSKHEQIGCLMLDLGALDLSKLIEDWAELDQPSSDVNTEIPLGEICMSLKQDPDEEKLFVTILEAKGLRKHDEEDLYDPFLRLSLEEXXXXXXXXXXXXXXXXXPNPYYNEDFEFQLSAELSTKVQLVVTAFNCSNNNIKHSMPIGNIVLGPTITGSGYKHWKEIISNSKRTIVRWHGLVEVVDN 1119
            LG+L Y + Y  +  SL V +    +L  ++ GGTSDPYVK++L    K K +TK++R++ NPVFNE FTF +   E+  QTL+   +DFDRF KH+QIG + + LG +DL+  +E    ++ P      E  LGE+C++L+  P++ KL V ++E K L+K D   L DP++++ L  G   + KKK T   K   NPYYNE F F +++E   +V L VT      + +  +  IG +++G   TG   K W ++++  +R++ +WH LV   D+
Sbjct:   16 LGRLQYKLDYDFDKNSLTVVIIQAEELPAMDLGGTSDPYVKLFLLPDKKKKLQTKVQRKSLNPVFNESFTFKIPFNEIGGQTLVLNVFDFDRFGKHDQIGQISIPLGKVDLAATLERTDLIESPP-----ENRLGEVCLALRYVPNKNKLSVVVMECKNLKKMDVLGLSDPYVKIYLMMGTKRLEKKKTTIKMKTL-NPYYNESFSFDVTSEKMQRVHLHVTV--SDYDRVGSNERIGQVIIGTCATGVALKQWNDMLATPRRSVAQWHTLVPFNDD 284

[Close]

Query:  289 LGKLVYAIKYFPESESLRVTVKSGHDLIKLNTGGTSDPYVKVWLKEKPKLKFETKIKRRTRNPVFNEDFTFTVSPEELPTQTLIFFFYDFDRFSKHEQIGCLMLDLGALDLSKLIEDWAELDQPSSDVNTEIPLGEICMSLKQDPDEEKLFVTILEAKGLRKHDEEDLYDPFLRLSLEEXXXXXXXXXXXXXXXXXPNPYYNEDFEFQLSAELSTKVQLVVTAFNCSNNNIKHSMPIGNIVLGPTITGSGYKHWKEIISNSKRTIVRWHGLVEVVDN 1119
            LG+L Y + Y  +  SL V +    +L  ++ GGTSDPYVK++L    K K +TK++R++ NPVFNE FTF +   E+  QTL+   +DFDRF KH+QIG + + LG +DL+  +E    ++ P      E  LGE+C++L+  P++ KL V ++E K L+K D   L DP++++ L  G   + KKK T   K   NPYYNE F F +++E   +V L VT      + +  +  IG +++G   TG   K W ++++  +R++ +WH LV   D+
Sbjct:   16 LGRLQYKLDYDFDKNSLTVVIIQAEELPAMDLGGTSDPYVKLFLLPDKKKKLQTKVQRKSLNPVFNESFTFKIPFNEIGGQTLVLNVFDFDRFGKHDQIGQISIPLGKVDLAATLERTDLIESPP-----ENRLGEVCLALRYVPNKNKLSVVVMECKNLKKMDVLGLSDPYVKIYLMMGTKRLEKKKTTIKMKTL-NPYYNESFSFDVTSEKMQRVHLHVTV--SDYDRVGSNERIGQVIIGTCATGVALKQWNDMLATPRRSVAQWHTLVPFNDD 284

[Close]

BLAST of Synaptotagmin 1 vs. Ensembl Celegans
Match: snt-2 (Synaptotagmin 2 [Source:UniProtKB/Swiss-Prot;Acc:K8FE10])

HSP 1 Score: 161.384 bits (407), Expect = 6.181e-45
Identity = 101/287 (35.19%), Postives = 162/287 (56.45%), Query Frame = 1

Query:  292 GKLVYAIKYFPESESLRVTVKSGHDLIKLNTGGTSDPYVKVWLKEKPKLKFETKIKRRTRNPVFNEDFTFTVSPEELPTQTLIFFFYDFDRFSKHEQIGCLMLDLGALDLSKLIEDWAELDQPSSDVNTEIPLGEICMSLKQDPDEEKLFVTILEAKGLRKHDEEDLYDPFLRLSLEEXXXXXXXXXXXXXXXXXPNPYYNEDFEFQLSAELSTKVQLVVTAFN---CSNNNIKHSMPIGNIVLG------PTITGSGYKHWKEIISNSKRTIVRWHGLVEVVDNKK 1125
            G + + ++Y  E   L VT+ S  DL  ++  G SDPYVKV++  + K KFET+I R T NP +NE F F++   EL ++TL+   YD+DR SK +++G L + L ++D     +    L +P  D   E  LG+IC S +  P    + +TI+EA+ L+K D     DP++++ L  G  ++ KKK +   K   NPYYNE F+F++   +  KV L+V+ ++    S N+      IG + LG      P IT +  + W E+++ S+R +V+WH L E ++ +K
Sbjct:   85 GNIHFRVEYDFEQSKLSVTIVSASDLPAMDRNGMSDPYVKVYVLPERKQKFETRIIRNTLNPTYNETFQFSIPFNELHSKTLMLVVYDYDRLSKDDKMGQLSVPLESIDFGITTDIERPLQKPEKDDEKECRLGDICFSTRYRPATGTVTLTIMEARNLKKMDVGGSSDPYVKIYLHHGRKLLSKKKTSRKYKTL-NPYYNESFQFKIEPHMIEKVHLIVSVWDYDKMSKNDF-----IGEVTLGSKHLNLPQITHACSEQWAEMMT-SRRPVVQWHTLQERMEKEK 364

HSP 2 Score: 83.1889 bits (204), Expect = 3.694e-17
Identity = 47/142 (33.10%), Postives = 81/142 (57.04%), Query Frame = 1

Query:  262 KALEKPKES------LGKLVYAIKYFPESESLRVTVKSGHDLIKLNTGGTSDPYVKVWLKEKPKL--KFETKIKRRTRNPVFNEDFTFTVSPEELPTQTLIFFFYDFDRFSKHEQIGCLMLDLGALDLSKLI----EDWAEL 651
            + L+KP++       LG + ++ +Y P + ++ +T+    +L K++ GG+SDPYVK++L    KL  K +T  K +T NP +NE F F + P  +    LI   +D+D+ SK++ IG + L    L+L ++     E WAE+
Sbjct:  202 RPLQKPEKDDEKECRLGDICFSTRYRPATGTVTLTIMEARNLKKMDVGGSSDPYVKIYLHHGRKLLSKKKTSRKYKTLNPYYNESFQFKIEPHMIEKVHLIVSVWDYDKMSKNDFIGEVTLGSKHLNLPQITHACSEQWAEM 343

[Close]

BLAST of Synaptotagmin 1 vs. Ensembl Fly
Match: Syt1 (gene:FBgn0004242 transcript:FBtr0077726)

HSP 1 Score: 198.749 bits (504), Expect = 8.580e-58
Identity = 118/277 (42.60%), Postives = 171/277 (61.73%), Query Frame = 1

Query:  274 KPKESLGKLVYAIKYFPESESLRVTVKSGHDLIKLNTGGTSDPYVKVWLKEKPKLKFETKIKRRTRNPVFNEDFTFTVSP-EELPTQTLIFFFYDFDRFSKHEQIGCLMLDLGALDLSKLIEDWAELDQPSSDVNTEIPLGEICMSLKQDPDEEKLFVTILEAKGLRKHDEEDLYDPFLRLSLEEXXXXXXXXXXXXXXXXXPNPYYNEDFEFQLSAELSTKVQLVVTAFNCSNNNIKHSMPIGNIVLGPTITGSGYKHWKEIISNSKRTIVRWHGL 1101
            + ++ LG+L + ++Y   S SL VTV    +L  L+ GGTSDPYVKV+L    K KFETK+ R+T +PVFNE FTF   P  +   +TL+F  +DFDRFSKH+QIG + + L  +DL++ IE+W +L     +   E  LG+IC SL+  P   KL V ILEAK L+K D   L DP++++++ + G  + KKK +  K    NPYYNE F F++  E   K+ LVVT  +   + I  S PIG  +LG   TG+  +HW +++++ +R I +WH L
Sbjct:  188 QSEQKLGRLNFKLEYDFNSNSLAVTVIQAEELPALDMGGTSDPYVKVYLLPDKKKKFETKVHRKTLSPVFNETFTFKSLPYADAMNKTLVFAIFDFDRFSKHDQIGEVKVPLCTIDLAQTIEEWRDLVSVEGEGGQE-KLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIAIMQNGKRLKKKKTSIKKCTL-NPYYNESFSFEVPFEQIQKICLVVTVVD--YDRIGTSEPIGRCILGCMGTGTELRHWSDMLASPRRPIAQWHTL 460

[Close]

BLAST of Synaptotagmin 1 vs. Ensembl Fly
Match: Syt1 (gene:FBgn0004242 transcript:FBtr0077728)

HSP 1 Score: 198.364 bits (503), Expect = 1.088e-57
Identity = 118/277 (42.60%), Postives = 171/277 (61.73%), Query Frame = 1

Query:  274 KPKESLGKLVYAIKYFPESESLRVTVKSGHDLIKLNTGGTSDPYVKVWLKEKPKLKFETKIKRRTRNPVFNEDFTFTVSP-EELPTQTLIFFFYDFDRFSKHEQIGCLMLDLGALDLSKLIEDWAELDQPSSDVNTEIPLGEICMSLKQDPDEEKLFVTILEAKGLRKHDEEDLYDPFLRLSLEEXXXXXXXXXXXXXXXXXPNPYYNEDFEFQLSAELSTKVQLVVTAFNCSNNNIKHSMPIGNIVLGPTITGSGYKHWKEIISNSKRTIVRWHGL 1101
            + ++ LG+L + ++Y   S SL VTV    +L  L+ GGTSDPYVKV+L    K KFETK+ R+T +PVFNE FTF   P  +   +TL+F  +DFDRFSKH+QIG + + L  +DL++ IE+W +L     +   E  LG+IC SL+  P   KL V ILEAK L+K D   L DP++++++ + G  + KKK +  K    NPYYNE F F++  E   K+ LVVT  +   + I  S PIG  +LG   TG+  +HW +++++ +R I +WH L
Sbjct:  186 QSEQKLGRLNFKLEYDFNSNSLAVTVIQAEELPALDMGGTSDPYVKVYLLPDKKKKFETKVHRKTLSPVFNETFTFKSLPYADAMNKTLVFAIFDFDRFSKHDQIGEVKVPLCTIDLAQTIEEWRDLVSVEGEGGQE-KLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIAIMQNGKRLKKKKTSIKKCTL-NPYYNESFSFEVPFEQIQKICLVVTVVD--YDRIGTSEPIGRCILGCMGTGTELRHWSDMLASPRRPIAQWHTL 458

[Close]

BLAST of Synaptotagmin 1 vs. Ensembl Fly
Match: Syt1 (gene:FBgn0004242 transcript:FBtr0345331)

HSP 1 Score: 198.364 bits (503), Expect = 1.088e-57
Identity = 118/277 (42.60%), Postives = 171/277 (61.73%), Query Frame = 1

Query:  274 KPKESLGKLVYAIKYFPESESLRVTVKSGHDLIKLNTGGTSDPYVKVWLKEKPKLKFETKIKRRTRNPVFNEDFTFTVSP-EELPTQTLIFFFYDFDRFSKHEQIGCLMLDLGALDLSKLIEDWAELDQPSSDVNTEIPLGEICMSLKQDPDEEKLFVTILEAKGLRKHDEEDLYDPFLRLSLEEXXXXXXXXXXXXXXXXXPNPYYNEDFEFQLSAELSTKVQLVVTAFNCSNNNIKHSMPIGNIVLGPTITGSGYKHWKEIISNSKRTIVRWHGL 1101
            + ++ LG+L + ++Y   S SL VTV    +L  L+ GGTSDPYVKV+L    K KFETK+ R+T +PVFNE FTF   P  +   +TL+F  +DFDRFSKH+QIG + + L  +DL++ IE+W +L     +   E  LG+IC SL+  P   KL V ILEAK L+K D   L DP++++++ + G  + KKK +  K    NPYYNE F F++  E   K+ LVVT  +   + I  S PIG  +LG   TG+  +HW +++++ +R I +WH L
Sbjct:  186 QSEQKLGRLNFKLEYDFNSNSLAVTVIQAEELPALDMGGTSDPYVKVYLLPDKKKKFETKVHRKTLSPVFNETFTFKSLPYADAMNKTLVFAIFDFDRFSKHDQIGEVKVPLCTIDLAQTIEEWRDLVSVEGEGGQE-KLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIAIMQNGKRLKKKKTSIKKCTL-NPYYNESFSFEVPFEQIQKICLVVTVVD--YDRIGTSEPIGRCILGCMGTGTELRHWSDMLASPRRPIAQWHTL 458

[Close]

BLAST of Synaptotagmin 1 vs. Ensembl Fly
Match: Syt1 (gene:FBgn0004242 transcript:FBtr0077727)

HSP 1 Score: 198.364 bits (503), Expect = 1.088e-57
Identity = 118/277 (42.60%), Postives = 171/277 (61.73%), Query Frame = 1

Query:  274 KPKESLGKLVYAIKYFPESESLRVTVKSGHDLIKLNTGGTSDPYVKVWLKEKPKLKFETKIKRRTRNPVFNEDFTFTVSP-EELPTQTLIFFFYDFDRFSKHEQIGCLMLDLGALDLSKLIEDWAELDQPSSDVNTEIPLGEICMSLKQDPDEEKLFVTILEAKGLRKHDEEDLYDPFLRLSLEEXXXXXXXXXXXXXXXXXPNPYYNEDFEFQLSAELSTKVQLVVTAFNCSNNNIKHSMPIGNIVLGPTITGSGYKHWKEIISNSKRTIVRWHGL 1101
            + ++ LG+L + ++Y   S SL VTV    +L  L+ GGTSDPYVKV+L    K KFETK+ R+T +PVFNE FTF   P  +   +TL+F  +DFDRFSKH+QIG + + L  +DL++ IE+W +L     +   E  LG+IC SL+  P   KL V ILEAK L+K D   L DP++++++ + G  + KKK +  K    NPYYNE F F++  E   K+ LVVT  +   + I  S PIG  +LG   TG+  +HW +++++ +R I +WH L
Sbjct:  186 QSEQKLGRLNFKLEYDFNSNSLAVTVIQAEELPALDMGGTSDPYVKVYLLPDKKKKFETKVHRKTLSPVFNETFTFKSLPYADAMNKTLVFAIFDFDRFSKHDQIGEVKVPLCTIDLAQTIEEWRDLVSVEGEGGQE-KLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIAIMQNGKRLKKKKTSIKKCTL-NPYYNESFSFEVPFEQIQKICLVVTVVD--YDRIGTSEPIGRCILGCMGTGTELRHWSDMLASPRRPIAQWHTL 458

[Close]

BLAST of Synaptotagmin 1 vs. Ensembl Fly
Match: Syt1 (gene:FBgn0004242 transcript:FBtr0343993)

HSP 1 Score: 197.208 bits (500), Expect = 3.029e-57
Identity = 117/277 (42.24%), Postives = 171/277 (61.73%), Query Frame = 1

Query:  274 KPKESLGKLVYAIKYFPESESLRVTVKSGHDLIKLNTGGTSDPYVKVWLKEKPKLKFETKIKRRTRNPVFNEDFTFTVSP-EELPTQTLIFFFYDFDRFSKHEQIGCLMLDLGALDLSKLIEDWAELDQPSSDVNTEIPLGEICMSLKQDPDEEKLFVTILEAKGLRKHDEEDLYDPFLRLSLEEXXXXXXXXXXXXXXXXXPNPYYNEDFEFQLSAELSTKVQLVVTAFNCSNNNIKHSMPIGNIVLGPTITGSGYKHWKEIISNSKRTIVRWHGL 1101
            + ++ LG+L + ++Y   S SL VTV    +L  L+ GGTSDPYVKV+L    K KFETK+ R+T +PVFNE FTF   P  +   +TL+F  +DFDRFSKH+QIG + + L  +DL++ IE+W +L     +   +  LG+IC SL+  P   KL V ILEAK L+K D   L DP++++++ + G  + KKK +  K    NPYYNE F F++  E   K+ LVVT  +   + I  S PIG  +LG   TG+  +HW +++++ +R I +WH L
Sbjct:  188 QSEQKLGRLNFKLEYDFNSNSLAVTVIQAEELPALDMGGTSDPYVKVYLLPDKKKKFETKVHRKTLSPVFNETFTFKSLPYADAMNKTLVFAIFDFDRFSKHDQIGEVKVPLCTIDLAQTIEEWRDLVSVEGEGGQK--LGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIAIMQNGKRLKKKKTSIKKCTL-NPYYNESFSFEVPFEQIQKICLVVTVVD--YDRIGTSEPIGRCILGCMGTGTELRHWSDMLASPRRPIAQWHTL 459

[Close]

BLAST of Synaptotagmin 1 vs. Ensembl Zebrafish
Match: syt1a (synaptotagmin Ia [Source:ZFIN;Acc:ZDB-GENE-040718-165])

HSP 1 Score: 194.512 bits (493), Expect = 1.372e-56
Identity = 114/271 (42.07%), Postives = 164/271 (60.52%), Query Frame = 1

Query:  289 LGKLVYAIKYFPESESLRVTVKSGHDLIKLNTGGTSDPYVKVWLKEKPKLKFETKIKRRTRNPVFNEDFTFTVSPEELPTQTLIFFFYDFDRFSKHEQIGCLMLDLGALDLSKLIEDWAELDQPSSDVNTEIPLGEICMSLKQDPDEEKLFVTILEAKGLRKHDEEDLYDPFLRLSLEEXXXXXXXXXXXXXXXXXPNPYYNEDFEFQLSAELSTKVQLVVTAFNCSNNNIKHSMPIGNIVLGPTITGSGYKHWKEIISNSKRTIVRWHGL 1101
            LGKL Y++ Y     +L V +    +L  ++ GGTSDPYVKV+L    K KFETK+ R+T NPVFNE FTF V   EL  +TL+   YDFDRFSKH+ IG + + +  +D S + E+W +L   S++   +  LG+IC SL+  P   KL V +LEAK L+K D   L DP++++ L + G  + KKK T  K    NPYYNE F F++  E   KVQ+V+T  +   + I  +  IG + +G   TG+  +HW ++++N +R I +WH L
Sbjct:  139 LGKLQYSMDYNFTENTLIVGIIQAAELPAMDMGGTSDPYVKVYLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYTELGGKTLVMTVYDFDRFSKHDAIGDVKVPMNKVDFSHVTEEWRDLQ--SAEKEEQEKLGDICFSLRYVPTAGKLTVVVLEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTL-NPYYNESFSFEVPFEQIQKVQVVITVLDY--DKIGKNDAIGKVFVGLNSTGTELRHWSDMLANPRRPIAQWHVL 404

HSP 2 Score: 64.6994 bits (156), Expect = 8.209e-11
Identity = 38/121 (31.40%), Postives = 67/121 (55.37%), Query Frame = 1

Query:  259 LKALEKP-KESLGKLVYAIKYFPESESLRVTVKSGHDLIKLNTGGTSDPYVKVWLKEKPKLKFETKIKRRTR--NPVFNEDFTFTVSPEELPTQTLIFFFYDFDRFSKHEQIGCLMLDLGA 612
            L++ EK  +E LG + ++++Y P +  L V V    +L K++ GG SDPYVK+ L +  K   + K   +    NP +NE F+F V  E++    ++    D+D+  K++ IG + + L +
Sbjct:  259 LQSAEKEEQEKLGDICFSLRYVPTAGKLTVVVLEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVITVLDYDKIGKNDAIGKVFVGLNS 379

[Close]

Query:  289 LGKLVYAIKYFPESESLRVTVKSGHDLIKLNTGGTSDPYVKVWLKEKPKLKFETKIKRRTRNPVFNEDFTFTVSPEELPTQTLIFFFYDFDRFSKHEQIGCLMLDLGALDLSKLIEDWAELDQPSSDVNTEIPLGEICMSLKQDPDEEKLFVTILEAKGLRKHDEEDLYDPFLRLSLEEXXXXXXXXXXXXXXXXXPNPYYNEDFEFQLSAELSTKVQLVVTAFNCSNNNIKHSMPIGNIVLGPTITGSGYKHWKEIISNSKRTIVRWHGL 1101
            LGKL Y++ Y     +L V +    +L  ++ GGTSDPYVKV+L    K KFETK+ R+T NPVFNE FTF V   EL  +TL+   YDFDRFSKH+ IG + + +  +D S + E+W +L   S++   +  LG+IC SL+  P   KL V +LEAK L+K D   L DP++++ L + G  + KKK T  K    NPYYNE F F++  E   KVQ+V+T  +   + I  +  IG + +G   TG+  +HW ++++N +R I +WH L
Sbjct:  139 LGKLQYSMDYNFTENTLIVGIIQAAELPAMDMGGTSDPYVKVYLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYTELGGKTLVMTVYDFDRFSKHDAIGDVKVPMNKVDFSHVTEEWRDLQ--SAEKEEQEKLGDICFSLRYVPTAGKLTVVVLEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTL-NPYYNESFSFEVPFEQIQKVQVVITVLDY--DKIGKNDAIGKVFVGLNSTGTELRHWSDMLANPRRPIAQWHVL 404

HSP 2 Score: 64.6994 bits (156), Expect = 8.209e-11
Identity = 38/121 (31.40%), Postives = 67/121 (55.37%), Query Frame = 1

Query:  259 LKALEKP-KESLGKLVYAIKYFPESESLRVTVKSGHDLIKLNTGGTSDPYVKVWLKEKPKLKFETKIKRRTR--NPVFNEDFTFTVSPEELPTQTLIFFFYDFDRFSKHEQIGCLMLDLGA 612
            L++ EK  +E LG + ++++Y P +  L V V    +L K++ GG SDPYVK+ L +  K   + K   +    NP +NE F+F V  E++    ++    D+D+  K++ IG + + L +
Sbjct:  259 LQSAEKEEQEKLGDICFSLRYVPTAGKLTVVVLEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVITVLDYDKIGKNDAIGKVFVGLNS 379

[Close]

BLAST of Synaptotagmin 1 vs. Ensembl Zebrafish
Match: syt2a (synaptotagmin IIa [Source:ZFIN;Acc:ZDB-GENE-060503-315])

HSP 1 Score: 189.119 bits (479), Expect = 1.645e-54
Identity = 108/271 (39.85%), Postives = 165/271 (60.89%), Query Frame = 1

Query:  289 LGKLVYAIKYFPESESLRVTVKSGHDLIKLNTGGTSDPYVKVWLKEKPKLKFETKIKRRTRNPVFNEDFTFTVSPEELPTQTLIFFFYDFDRFSKHEQIGCLMLDLGALDLSKLIEDWAELDQPSSDVNTEIPLGEICMSLKQDPDEEKLFVTILEAKGLRKHDEEDLYDPFLRLSLEEXXXXXXXXXXXXXXXXXPNPYYNEDFEFQLSAELSTKVQLVVTAFNCSNNNIKHSMPIGNIVLGPTITGSGYKHWKEIISNSKRTIVRWHGL 1101
            LGKL +++ Y   +  L V +    DL+ +++GGTSDPYVKV++    K K++TK+ ++T NPVFNE F F +   E+  +TL+   YDFDRFSKH+ IG + + +  LDL++ IE W +LD  S++      LG+IC+SL+  P   KL + ILEAK L+K D   L DP++++ L + G  + KKK T  K    NPYYNE F F++  +   K+Q V+T  +   + I  +  IG I +G    G+  +HW ++++N +R I +WH L
Sbjct:  148 LGKLQFSLDYDFSASQLTVGILQAADLLSMDSGGTSDPYVKVFILPDKKKKYDTKVHKKTLNPVFNETFHFKIPFTEMGGKTLVMSVYDFDRFSKHDVIGEVKIPMNTLDLAQPIEQWRDLD--SAEKEEPEKLGDICISLRYVPTAGKLTICILEAKNLKKMDVGGLSDPYVKIHLLQNGKRLKKKKTTVKKNTL-NPYYNESFSFEIPQDQMQKIQAVITVLD--YDKIGKNDAIGKIWVGSKAQGTELRHWSDMLANPRRPIAQWHPL 413

HSP 2 Score: 58.151 bits (139), Expect = 9.728e-9
Identity = 30/104 (28.85%), Postives = 55/104 (52.88%), Query Frame = 1

Query:  283 ESLGKLVYAIKYFPESESLRVTVKSGHDLIKLNTGGTSDPYVKVWLKEKPKLKFETKIKRRTR--NPVFNEDFTFTVSPEELPTQTLIFFFYDFDRFSKHEQIG 588
            E LG +  +++Y P +  L + +    +L K++ GG SDPYVK+ L +  K   + K   +    NP +NE F+F +  +++     +    D+D+  K++ IG
Sbjct:  277 EKLGDICISLRYVPTAGKLTICILEAKNLKKMDVGGLSDPYVKIHLLQNGKRLKKKKTTVKKNTLNPYYNESFSFEIPQDQMQKIQAVITVLDYDKIGKNDAIG 380

[Close]

Query:  289 LGKLVYAIKYFPESESLRVTVKSGHDLIKLNTGGTSDPYVKVWLKEKPKLKFETKIKRRTRNPVFNEDFTFTVSPEELPTQTLIFFFYDFDRFSKHEQIGCLMLDLGALDLSKLIEDWAELDQPSSDVNTEIPLGEICMSLKQDPDEEKLFVTILEAKGLRKHDEEDLYDPFLRLSLEEXXXXXXXXXXXXXXXXXPNPYYNEDFEFQLSAELSTKVQLVVTAFNCSNNNIKHSMPIGNIVLGPTITGSGYKHWKEIISNSKRTIVRWHGL 1101
            LGKL +++ Y   +  L V +    DL+ +++GGTSDPYVKV++    K K++TK+ ++T NPVFNE F F +   E+  +TL+   YDFDRFSKH+ IG + + +  LDL++ IE W +LD  S++      LG+IC+SL+  P   KL + ILEAK L+K D   L DP++++ L + G  + KKK T  K    NPYYNE F F++  +   K+Q V+T  +   + I  +  IG I +G    G+  +HW ++++N +R I +WH L
Sbjct:  148 LGKLQFSLDYDFSASQLTVGILQAADLLSMDSGGTSDPYVKVFILPDKKKKYDTKVHKKTLNPVFNETFHFKIPFTEMGGKTLVMSVYDFDRFSKHDVIGEVKIPMNTLDLAQPIEQWRDLD--SAEKEEPEKLGDICISLRYVPTAGKLTICILEAKNLKKMDVGGLSDPYVKIHLLQNGKRLKKKKTTVKKNTL-NPYYNESFSFEIPQDQMQKIQAVITVLD--YDKIGKNDAIGKIWVGSKAQGTELRHWSDMLANPRRPIAQWHPL 413

HSP 2 Score: 58.151 bits (139), Expect = 9.728e-9
Identity = 30/104 (28.85%), Postives = 55/104 (52.88%), Query Frame = 1

Query:  283 ESLGKLVYAIKYFPESESLRVTVKSGHDLIKLNTGGTSDPYVKVWLKEKPKLKFETKIKRRTR--NPVFNEDFTFTVSPEELPTQTLIFFFYDFDRFSKHEQIG 588
            E LG +  +++Y P +  L + +    +L K++ GG SDPYVK+ L +  K   + K   +    NP +NE F+F +  +++     +    D+D+  K++ IG
Sbjct:  277 EKLGDICISLRYVPTAGKLTICILEAKNLKKMDVGGLSDPYVKIHLLQNGKRLKKKKTTVKKNTLNPYYNESFSFEIPQDQMQKIQAVITVLDYDKIGKNDAIG 380

[Close]

BLAST of Synaptotagmin 1 vs. Ensembl Zebrafish
Match: syt5b (synaptotagmin Vb [Source:ZFIN;Acc:ZDB-GENE-050522-134])

HSP 1 Score: 179.104 bits (453), Expect = 5.966e-51
Identity = 104/272 (38.24%), Postives = 161/272 (59.19%), Query Frame = 1

Query:  286 SLGKLVYAIKYFPESESLRVTVKSGHDLIKLNTGGTSDPYVKVWLKEKPKLKFETKIKRRTRNPVFNEDFTFTVSPEELPTQTLIFFFYDFDRFSKHEQIGCLMLDLGALDLSKLIEDWAELDQPSSDVNTEIPLGEICMSLKQDPDEEKLFVTILEAKGLRKHDEEDLYDPFLRLSLEEXXXXXXXXXXXXXXXXXPNPYYNEDFEFQLSAELSTKVQLVVTAFNCSNNNIKHSMPIGNIVLGPTITGSGYKHWKEIISNSKRTIVRWHGL 1101
            +LGKL +++ Y      L V +    DL  ++ GGTSDPYVKV+L    K KFETK++R+   PVFNE F F +   EL  +TL+   +DFDRF KH+ IG + + +  +DL++ + +W EL+    +       G++C+SL+  P   KL V I+EAK L+K D   L DP++++ L+  G  + KKK T  K    NPY+NE F F++  E   KVQL++T ++   + +  + PIG   +G   TG G +HW ++++N +R + +WH L
Sbjct:  133 NLGKLEFSLDYNFTDAQLIVGILQAQDLAAMDIGGTSDPYVKVYLLPDKKKKFETKVQRKNLCPVFNETFIFKIPYAELGGKTLVLQVFDFDRFGKHDVIGQIKIPMNCVDLAQPLHEWRELENGEKEEEKL---GDVCISLRYVPTAGKLTVNIMEAKNLKKMDVGGLSDPYVKIVLQHNGKRLKKKKTTVKKNTL-NPYFNESFSFEVPFEQIQKVQLLITVYD--YDKLGSNDPIGKTFIGYGATGVGLRHWSDMLANPRRPVAQWHTL 398

HSP 2 Score: 65.0846 bits (157), Expect = 7.298e-11
Identity = 42/147 (28.57%), Postives = 74/147 (50.34%), Query Frame = 1

Query:  292 GKLVYAIKYFPESESLRVTVKSGHDLIKLNTGGTSDPYVKVWLKEKPKLKFETKIKRRTR--NPVFNEDFTFTVSPEELPTQTLIFFFYDFDRFSKHEQIGCLMLDLGALDLSKLIEDWAEL----DQPSSDVNTEIPLGEICMSLK 714
            G +  +++Y P +  L V +    +L K++ GG SDPYVK+ L+   K   + K   +    NP FNE F+F V  E++    L+   YD+D+   ++ IG   +  GA  +   +  W+++     +P +  +T  P  E+  +LK
Sbjct:  265 GDVCISLRYVPTAGKLTVNIMEAKNLKKMDVGGLSDPYVKIVLQHNGKRLKKKKTTVKKNTLNPYFNESFSFEVPFEQIQKVQLLITVYDYDKLGSNDPIGKTFIGYGATGVG--LRHWSDMLANPRRPVAQWHTLQPEEEVEAALK 409

[Close]

BLAST of Synaptotagmin 1 vs. Ensembl Xenopus
Match: SYT5 (synaptotagmin 5 [Source:NCBI gene;Acc:100493612])

HSP 1 Score: 206.838 bits (525), Expect = 3.390e-61
Identity = 119/277 (42.96%), Postives = 171/277 (61.73%), Query Frame = 1

Query:  271 EKPKESLGKLVYAIKYFPESESLRVTVKSGHDLIKLNTGGTSDPYVKVWLKEKPKLKFETKIKRRTRNPVFNEDFTFTVSPEELPTQTLIFFFYDFDRFSKHEQIGCLMLDLGALDLSKLIEDWAELDQPSSDVNTEIPLGEICMSLKQDPDEEKLFVTILEAKGLRKHDEEDLYDPFLRLSLEEXXXXXXXXXXXXXXXXXPNPYYNEDFEFQLSAELSTKVQLVVTAFNCSNNNIKHSMPIGNIVLGPTITGSGYKHWKEIISNSKRTIVRWHGL 1101
            EKP+E LGKL Y++ Y  ++  L V +    DL  L+ GGTSDPYVKV+L    K K+ETK+ R+T NP FNE FTF V   EL  +TL+   YDFDRFSKH+ IG + + +  +DL+ +IE+W +L   S++   +  LG+IC SL+  P   KL V +LEAK L+K D   L DP++++ L + G  + KKK T  K    NPYYNE F F++  E   KVQ+V+T  +   + +  +  IG I +G   TG+  +HW ++++N +R I +WH L
Sbjct:  130 EKPQEKLGKLQYSLDYDFQTGQLVVGIIQAADLPALDIGGTSDPYVKVYLLPDKKKKYETKVHRKTLNPTFNESFTFKVPYAELGGKTLVMSVYDFDRFSKHDAIGEVRVHMNTVDLAHVIEEWQDLQ--SAEKEEQEKLGDICFSLRYVPTAGKLTVIVLEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTL-NPYYNESFSFEVPFEQIQKVQVVLTVLDY--DKLGKNEAIGKIFVGCNATGTELRHWSDMLANPRRPIAQWHTL 401

HSP 2 Score: 65.855 bits (159), Expect = 5.202e-11
Identity = 39/121 (32.23%), Postives = 66/121 (54.55%), Query Frame = 1

Query:  259 LKALEKP-KESLGKLVYAIKYFPESESLRVTVKSGHDLIKLNTGGTSDPYVKVWLKEKPKLKFETKIKRRTR--NPVFNEDFTFTVSPEELPTQTLIFFFYDFDRFSKHEQIGCLMLDLGA 612
            L++ EK  +E LG + ++++Y P +  L V V    +L K++ GG SDPYVK+ L +  K   + K   +    NP +NE F+F V  E++    ++    D+D+  K+E IG + +   A
Sbjct:  256 LQSAEKEEQEKLGDICFSLRYVPTAGKLTVIVLEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVLTVLDYDKLGKNEAIGKIFVGCNA 376

[Close]

BLAST of Synaptotagmin 1 vs. Ensembl Xenopus
Match: SYT5 (synaptotagmin 5 [Source:NCBI gene;Acc:100493612])

HSP 1 Score: 206.838 bits (525), Expect = 4.645e-61
Identity = 119/277 (42.96%), Postives = 171/277 (61.73%), Query Frame = 1

Query:  271 EKPKESLGKLVYAIKYFPESESLRVTVKSGHDLIKLNTGGTSDPYVKVWLKEKPKLKFETKIKRRTRNPVFNEDFTFTVSPEELPTQTLIFFFYDFDRFSKHEQIGCLMLDLGALDLSKLIEDWAELDQPSSDVNTEIPLGEICMSLKQDPDEEKLFVTILEAKGLRKHDEEDLYDPFLRLSLEEXXXXXXXXXXXXXXXXXPNPYYNEDFEFQLSAELSTKVQLVVTAFNCSNNNIKHSMPIGNIVLGPTITGSGYKHWKEIISNSKRTIVRWHGL 1101
            EKP+E LGKL Y++ Y  ++  L V +    DL  L+ GGTSDPYVKV+L    K K+ETK+ R+T NP FNE FTF V   EL  +TL+   YDFDRFSKH+ IG + + +  +DL+ +IE+W +L   S++   +  LG+IC SL+  P   KL V +LEAK L+K D   L DP++++ L + G  + KKK T  K    NPYYNE F F++  E   KVQ+V+T  +   + +  +  IG I +G   TG+  +HW ++++N +R I +WH L
Sbjct:  135 EKPQEKLGKLQYSLDYDFQTGQLVVGIIQAADLPALDIGGTSDPYVKVYLLPDKKKKYETKVHRKTLNPTFNESFTFKVPYAELGGKTLVMSVYDFDRFSKHDAIGEVRVHMNTVDLAHVIEEWQDLQ--SAEKEEQEKLGDICFSLRYVPTAGKLTVIVLEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTL-NPYYNESFSFEVPFEQIQKVQVVLTVLDY--DKLGKNEAIGKIFVGCNATGTELRHWSDMLANPRRPIAQWHTL 406

HSP 2 Score: 65.855 bits (159), Expect = 5.531e-11
Identity = 39/121 (32.23%), Postives = 66/121 (54.55%), Query Frame = 1

Query:  259 LKALEKP-KESLGKLVYAIKYFPESESLRVTVKSGHDLIKLNTGGTSDPYVKVWLKEKPKLKFETKIKRRTR--NPVFNEDFTFTVSPEELPTQTLIFFFYDFDRFSKHEQIGCLMLDLGA 612
            L++ EK  +E LG + ++++Y P +  L V V    +L K++ GG SDPYVK+ L +  K   + K   +    NP +NE F+F V  E++    ++    D+D+  K+E IG + +   A
Sbjct:  261 LQSAEKEEQEKLGDICFSLRYVPTAGKLTVIVLEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVLTVLDYDKLGKNEAIGKIFVGCNA 381

[Close]

BLAST of Synaptotagmin 1 vs. Ensembl Xenopus
Match: e2f4 (E2F transcription factor 4 [Source:Xenbase;Acc:XB-GENE-482721])

HSP 1 Score: 197.593 bits (501), Expect = 1.559e-57
Identity = 119/279 (42.65%), Postives = 169/279 (60.57%), Query Frame = 1

Query:  271 EKPKE--SLGKLVYAIKYFPESESLRVTVKSGHDLIKLNTGGTSDPYVKVWLKEKPKLKFETKIKRRTRNPVFNEDFTFTVSPEELPTQTLIFFFYDFDRFSKHEQIGCLMLDLGALDLSKLIEDWAELDQPSSDVNTEIPLGEICMSLKQDPDEEKLFVTILEAKGLRKHDEEDLYDPFLRLSLEEXXXXXXXXXXXXXXXXXPNPYYNEDFEFQLSAELSTKVQLVVTAFNCSNNNIKHSMPIGNIVLGPTITGSGYKHWKEIISNSKRTIVRWHGL 1101
            E+PKE   LGKL Y++ Y  ++  L V +    +L  L+ GGTSDPYVK++L    K KFETK+ R+T NPVFNE FTF V   EL  +TL+   YDFDRFSKH+ IG + + +  +D   + E+W +L   S++   +  LG+IC SL+  P   KL V ILEAK L+K D   L DP++++ L + G  + KKK T  K    NPYYNE F F++  E   KVQ+VVT  +   + I  +  IG + +G   TG+  +HW ++++N +R I +WH L
Sbjct:  138 EQPKEVEKLGKLQYSLDYDFQNNQLMVGIIQAAELPALDMGGTSDPYVKLFLMPDKKKKFETKVHRKTLNPVFNEQFTFKVPYAELGGKTLVLTVYDFDRFSKHDVIGDVKVPMNTVDFGHVTEEWRDL--VSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTL-NPYYNESFSFEVPFEQIQKVQVVVTVLDY--DKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTL 411

HSP 2 Score: 63.1586 bits (152), Expect = 4.127e-10
Identity = 34/112 (30.36%), Postives = 62/112 (55.36%), Query Frame = 1

Query:  259 LKALEKPKESLGKLVYAIKYFPESESLRVTVKSGHDLIKLNTGGTSDPYVKVWLKEKPKLKFETKIKRRTR--NPVFNEDFTFTVSPEELPTQTLIFFFYDFDRFSKHEQIG 588
            + A ++ +E LG + ++++Y P +  L V +    +L K++ GG SDPYVK+ L +  K   + K   +    NP +NE F+F V  E++    ++    D+D+  K++ IG
Sbjct:  267 VSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIG 378

[Close]

BLAST of Synaptotagmin 1 vs. Ensembl Xenopus
Match: syt8 (synaptotagmin 8 [Source:NCBI gene;Acc:100037878])

HSP 1 Score: 184.882 bits (468), Expect = 4.041e-53
Identity = 100/276 (36.23%), Postives = 162/276 (58.70%), Query Frame = 1

Query:  283 ESLGKLVYAIKYFPESESLRVTVKSGHDLIKLNTGGTSDPYVKVWLKEKPKLKFETKIKRRTRNPVFNEDFTFTVSPEELPTQTLIFFFYDFDRFSKHEQIGCLMLDLGALDLSKLIEDWAELDQPSSDVNTEIPLGEICMSLKQDPDEEKLFVTILEAKGLRKHDEEDLYDPFLRLSLEEXXXXXXXXXXXXXXXXXPNPYYNEDFEFQLSAELSTKVQLVVTAFNCSNNNIKHSMPIGNIVLGPTITGSGYKHWKEIISNSKRTIVRWHGLVEV 1110
            E  G++ Y+++Y  ++E L V VK    L  ++ GGTSDPY  V++    + KFETK+ R+T NPVFNE F F V+ EE+P  T +   +DF+RF KH+ IG +++ LG ++L  +IEDW +L  P+     E  LG+IC SL+  P   KL + ILEAK L++ D +   DP++++ L        +KK    K     PY+NE F F +S E    + L+++ ++  ++ +  +  IG + LG   +G+  +HW +++++ +R I +WH L E 
Sbjct:  104 EYRGRVQYSLEYNFQTEELTVGVKQAAALKAMDLGGTSDPYAIVYVTNDTRKKFETKVNRKTLNPVFNESFVFKVTQEEVPRTTAVVQIFDFNRFLKHDVIGEMVIPLGEVNLQHVIEDWKDLG-PAGKTEHE-HLGDICFSLRYVPSSGKLTIIILEAKNLKRMDSDGFSDPYVKVHLALNRKKWKRKKTAVKKSTL-KPYFNESFTFDVSLEQMKNLDLIISVWD--HDKVGKNEQIGKLFLGCRASGNALRHWSDMLAHPRRPIAQWHKLQEA 374

[Close]

BLAST of Synaptotagmin 1 vs. Ensembl Xenopus
Match: luzp2 (leucine zipper protein 2 [Source:Xenbase;Acc:XB-GENE-940667])

HSP 1 Score: 180.644 bits (457), Expect = 3.232e-51
Identity = 106/266 (39.85%), Postives = 162/266 (60.90%), Query Frame = 1

Query:  304 YAIKYFPESESLRVTVKSGHDLIKLNTGGTSDPYVKVWLKEKPKLKFETKIKRRTRNPVFNEDFTFTVSPEELPTQTLIFFFYDFDRFSKHEQIGCLMLDLGALDLSKLIEDWAELDQPSSDVNTEIPLGEICMSLKQDPDEEKLFVTILEAKGLRKHDEEDLYDPFLRLSLEEXXXXXXXXXXXXXXXXXPNPYYNEDFEFQLSAELSTKVQLVVTAFNCSNNNIKHSMPIGNIVLGPTITGSGYKHWKEIISNSKRTIVRWHGL 1101
            +++ Y  ++  ++V +    +L  L+ GGTSDPYVKV+     K K ETK+ R+T NP+FNE FTF +  +EL  +TL    YDFDRFSKH+ IG + + +  +DL + IE+W +L   S++      LG+IC+SL+  P   KL V ILEAK L+K D   L DP++++ L + G  + KKK T  KK   NPY+NE F F++  E   KVQ+V+T  +   + +  +  IG I +G   +G+  +HW ++++N +R I +WH L
Sbjct:  151 FSLDYDFQNNQMQVGIIQATELPALDMGGTSDPYVKVFFLPDKKKKHETKVHRKTLNPIFNETFTFKIPYQELGGKTLCMSIYDFDRFSKHDIIGEVKVPMNTVDLGQPIEEWRDLQ--SAEKEEPEKLGDICISLRYVPTAGKLTVCILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTVKKKTL-NPYFNESFSFEIPFEQIQKVQVVITVLDY--DKLGKNEAIGKIFVGCNASGTELRHWSDMLANPRRPIAQWHPL 411

HSP 2 Score: 65.0846 bits (157), Expect = 8.894e-11
Identity = 41/121 (33.88%), Postives = 70/121 (57.85%), Query Frame = 1

Query:  259 LKALEKPK-ESLGKLVYAIKYFPESESLRVTVKSGHDLIKLNTGGTSDPYVKVWLKEKPK--LKFETKIKRRTRNPVFNEDFTFTVSPEELPTQTLIFFFYDFDRFSKHEQIGCLMLDLGA 612
            L++ EK + E LG +  +++Y P +  L V +    +L K++ GG SDPYVK+ L +  K   K +T +K++T NP FNE F+F +  E++    ++    D+D+  K+E IG + +   A
Sbjct:  266 LQSAEKEEPEKLGDICISLRYVPTAGKLTVCILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFEIPFEQIQKVQVVITVLDYDKLGKNEAIGKIFVGCNA 386

[Close]

BLAST of Synaptotagmin 1 vs. Ensembl Mouse
Match: Syt1 (synaptotagmin I [Source:MGI Symbol;Acc:MGI:99667])

HSP 1 Score: 195.282 bits (495), Expect = 6.511e-57
Identity = 116/271 (42.80%), Postives = 163/271 (60.15%), Query Frame = 1

Query:  289 LGKLVYAIKYFPESESLRVTVKSGHDLIKLNTGGTSDPYVKVWLKEKPKLKFETKIKRRTRNPVFNEDFTFTVSPEELPTQTLIFFFYDFDRFSKHEQIGCLMLDLGALDLSKLIEDWAELDQPSSDVNTEIPLGEICMSLKQDPDEEKLFVTILEAKGLRKHDEEDLYDPFLRLSLEEXXXXXXXXXXXXXXXXXPNPYYNEDFEFQLSAELSTKVQLVVTAFNCSNNNIKHSMPIGNIVLGPTITGSGYKHWKEIISNSKRTIVRWHGL 1101
            LGKL Y++ Y  ++  L V +    +L  L+ GGTSDPYVKV+L    K KFETK+ R+T NPVFNE FTF V   EL  +TL+   YDFDRFSKH+ IG   + +  +D   + E+W +L   S++   +  LG+IC SL+  P   KL V ILEAK L+K D   L DP++++ L + G  + KKK T  K    NPYYNE F F++  E   KVQ+VVT  +   + I  +  IG + +G   TG+  +HW ++++N +R I +WH L
Sbjct:  142 LGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVTEEWRDLQ--SAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTL-NPYYNESFSFEVPFEQIQKVQVVVTVLDY--DKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTL 407

HSP 2 Score: 63.1586 bits (152), Expect = 3.035e-10
Identity = 36/113 (31.86%), Postives = 63/113 (55.75%), Query Frame = 1

Query:  259 LKALEKP-KESLGKLVYAIKYFPESESLRVTVKSGHDLIKLNTGGTSDPYVKVWLKEKPKLKFETKIKRRTR--NPVFNEDFTFTVSPEELPTQTLIFFFYDFDRFSKHEQIG 588
            L++ EK  +E LG + ++++Y P +  L V +    +L K++ GG SDPYVK+ L +  K   + K   +    NP +NE F+F V  E++    ++    D+D+  K++ IG
Sbjct:  262 LQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIG 374

[Close]

Query:  289 LGKLVYAIKYFPESESLRVTVKSGHDLIKLNTGGTSDPYVKVWLKEKPKLKFETKIKRRTRNPVFNEDFTFTVSPEELPTQTLIFFFYDFDRFSKHEQIGCLMLDLGALDLSKLIEDWAELDQPSSDVNTEIPLGEICMSLKQDPDEEKLFVTILEAKGLRKHDEEDLYDPFLRLSLEEXXXXXXXXXXXXXXXXXPNPYYNEDFEFQLSAELSTKVQLVVTAFNCSNNNIKHSMPIGNIVLGPTITGSGYKHWKEIISNSKRTIVRWHGL 1101
            LGKL Y++ Y  ++  L V +    +L  L+ GGTSDPYVKV+L    K KFETK+ R+T NPVFNE FTF V   EL  +TL+   YDFDRFSKH+ IG   + +  +D   + E+W +L   S++   +  LG+IC SL+  P   KL V ILEAK L+K D   L DP++++ L + G  + KKK T  K    NPYYNE F F++  E   KVQ+VVT  +   + I  +  IG + +G   TG+  +HW ++++N +R I +WH L
Sbjct:  142 LGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVTEEWRDLQ--SAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTL-NPYYNESFSFEVPFEQIQKVQVVVTVLDY--DKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTL 407

HSP 2 Score: 63.1586 bits (152), Expect = 3.035e-10
Identity = 36/113 (31.86%), Postives = 63/113 (55.75%), Query Frame = 1

Query:  259 LKALEKP-KESLGKLVYAIKYFPESESLRVTVKSGHDLIKLNTGGTSDPYVKVWLKEKPKLKFETKIKRRTR--NPVFNEDFTFTVSPEELPTQTLIFFFYDFDRFSKHEQIG 588
            L++ EK  +E LG + ++++Y P +  L V +    +L K++ GG SDPYVK+ L +  K   + K   +    NP +NE F+F V  E++    ++    D+D+  K++ IG
Sbjct:  262 LQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIG 374

[Close]

BLAST of Synaptotagmin 1 vs. Ensembl Mouse
Match: Syt2 (synaptotagmin II [Source:MGI Symbol;Acc:MGI:99666])

HSP 1 Score: 193.356 bits (490), Expect = 3.418e-56
Identity = 115/272 (42.28%), Postives = 166/272 (61.03%), Query Frame = 1

Query:  286 SLGKLVYAIKYFPESESLRVTVKSGHDLIKLNTGGTSDPYVKVWLKEKPKLKFETKIKRRTRNPVFNEDFTFTVSPEELPTQTLIFFFYDFDRFSKHEQIGCLMLDLGALDLSKLIEDWAELDQPSSDVNTEIPLGEICMSLKQDPDEEKLFVTILEAKGLRKHDEEDLYDPFLRLSLEEXXXXXXXXXXXXXXXXXPNPYYNEDFEFQLSAELSTKVQLVVTAFNCSNNNIKHSMPIGNIVLGPTITGSGYKHWKEIISNSKRTIVRWHGL 1101
            +LGKL +++ Y  ++  L V V    +L  L+ GGTSDPYVKV+L    K K+ETK+ R+T NP FNE FTF V  +EL  +TL+   YDFDRFSKH+ IG + + +  +DL + IE+W +L     +   +  LG+IC SL+  P   KL V ILEAK L+K D   L DP++++ L + G  + KKK T  KK   NPY+NE F F++  E   KVQ+VVT  +   + +  +  IG I +G   TG+  +HW ++++N +R I +WH L
Sbjct:  142 NLGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVKVFLLPDKKKKYETKVHRKTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVPMNTVDLGQPIEEWRDLQGGEKEEPEK--LGDICTSLRYVPTAGKLTVCILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTVKKKTL-NPYFNESFSFEIPFEQIQKVQVVVTVLDY--DKLGKNEAIGKIFVGSNATGTELRHWSDMLANPRRPIAQWHSL 408

[Close]

Query:  286 SLGKLVYAIKYFPESESLRVTVKSGHDLIKLNTGGTSDPYVKVWLKEKPKLKFETKIKRRTRNPVFNEDFTFTVSPEELPTQTLIFFFYDFDRFSKHEQIGCLMLDLGALDLSKLIEDWAELDQPSSDVNTEIPLGEICMSLKQDPDEEKLFVTILEAKGLRKHDEEDLYDPFLRLSLEEXXXXXXXXXXXXXXXXXPNPYYNEDFEFQLSAELSTKVQLVVTAFNCSNNNIKHSMPIGNIVLGPTITGSGYKHWKEIISNSKRTIVRWHGL 1101
            +LGKL +++ Y  ++  L V V    +L  L+ GGTSDPYVKV+L    K K+ETK+ R+T NP FNE FTF V  +EL  +TL+   YDFDRFSKH+ IG + + +  +DL + IE+W +L     +   +  LG+IC SL+  P   KL V ILEAK L+K D   L DP++++ L + G  + KKK T  KK   NPY+NE F F++  E   KVQ+VVT  +   + +  +  IG I +G   TG+  +HW ++++N +R I +WH L
Sbjct:  142 NLGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVKVFLLPDKKKKYETKVHRKTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVPMNTVDLGQPIEEWRDLQGGEKEEPEK--LGDICTSLRYVPTAGKLTVCILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTVKKKTL-NPYFNESFSFEIPFEQIQKVQVVVTVLDY--DKLGKNEAIGKIFVGSNATGTELRHWSDMLANPRRPIAQWHSL 408

[Close]

BLAST of Synaptotagmin 1 vs. Ensembl Mouse
Match: Syt5 (synaptotagmin V [Source:MGI Symbol;Acc:MGI:1926368])

HSP 1 Score: 159.844 bits (403), Expect = 7.157e-44
Identity = 101/274 (36.86%), Postives = 159/274 (58.03%), Query Frame = 1

Query:  280 KESLGKLVYAIKYFPESESLRVTVKSGHDLIKLNTGGTSDPYVKVWLKEKPKLKFETKIKRRTRNPVFNEDFTFTVSPEELPTQTLIFFFYDFDRFSKHEQIGCLMLDLGALDLSKLIEDWAELDQPSSDVNTEIPLGEICMSLKQDPDEEKLFVTILEAKGLRKHDEEDLYDPFLRLSLEEXXXXXXXXXXXXXXXXXPNPYYNEDFEFQLSAELSTKVQLVVTAFNCSNNNIKHSMPIGNIVLGPTITGSGYKHWKEIISNSKRTIVRWHGL 1101
            K  LG+L Y++ Y  ++  L V +     L  L+ GG+SDPYV V+L    + + ETK+ R+T NP F E F F V   EL  + L+   YDFDRFS+++ IG + + + +++L + ++ W EL     +   +  LG+IC SL+  P   KL V +LEAK L+K D   L DP++++ L +GG  V KKK T  K    NPYYNE F F++  +   KVQ+ +T  +   + +  +  IG + +G  + G+G +HW ++++N +R I +WH L
Sbjct:  106 KHQLGRLQYSLDYDFQTGQLLVGILQAQGLAALDLGGSSDPYVSVYLLPDKRRRHETKVHRQTLNPHFGETFAFKVPYVELGGRVLVMAVYDFDRFSRNDAIGEVRVPMSSVNLGRPVQAWRELQVAPKEEQEK--LGDICFSLRYVPTAGKLTVIVLEAKNLKKMDVGGLSDPYVKVHLLQGGKKVRKKKTTIKKNTL-NPYYNEAFSFEVPCDQVQKVQVELTVLD--YDKLGKNEAIGRVAVGAAVGGAGLRHWADMLANPRRPIAQWHSL 374

[Close]

BLAST of Synaptotagmin 1 vs. UniProt/SwissProt
Match: sp|P41823|SY65_APLCA (Synaptotagmin-1 OS=Aplysia californica OX=6500 GN=SYT1 PE=1 SV=2)

HSP 1 Score: 213.001 bits (541), Expect = 1.257e-62
Identity = 121/279 (43.37%), Postives = 172/279 (61.65%), Query Frame = 1

Query:  274 KPKESLGKLVYAIKYFPESESLRVTVKSGHDLIKLNTGGTSDPYVKVWLKEKPKLKFETKIKRRTRNPVFNEDFTFTVSPEELPTQTLIFFFYDFDRFSKHEQIGCLMLDLGALDLSKLIEDWAELDQPSSDVNTEIPLGEICMSLKQDPDEEKLFVTILEAKGLRKHDEEDLYDPFLRLSLEEXXXXXXXXXXXXXXXXXPNPYYNEDFEFQLSAELSTKVQLVVTAFNCSNNNIKHSMPIGNIVLGPTITGSGYKHWKEIISNSKRTIVRWHGLVEV 1110
            K +  LGKL +++ Y  +   L V V    DL  ++  GTSDPYVKV+L    K K+ETK+ R+T NPVFNE FTF V   E+ ++ L F  YDFDRFSKH+QIG + + L ++DL +++EDW +L  P ++   E  LG+IC SL+  P   KL V ILEAK L+K D   L DP+++++L +G   + KKK T  K    NPY+NE F F++  E   KV L++T  +   + I  S PIG  VLG   +G+  +HW ++++N +R I +WH L EV
Sbjct:  149 KSEVKLGKLQFSLDYDFQKGELSVNVIQAADLPGMDMSGTSDPYVKVYLLPDKKKKYETKVHRKTLNPVFNESFTFKVPYAEVGSKILTFAVYDFDRFSKHDQIGQVQVPLNSIDLGRVVEDWKDLQSPDTESEKENKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIALLQGTKRLKKKKTTIKKNTL-NPYFNESFGFEVPFEQIQKVTLIITVVDY--DRIGTSEPIGRCVLGCNSSGTELRHWSDMLANPRRPIAQWHTLQEV 424

[Close]

BLAST of Synaptotagmin 1 vs. UniProt/SwissProt
Match: sp|P21521|SY65_DROME (Synaptotagmin 1 OS=Drosophila melanogaster OX=7227 GN=Syt1 PE=1 SV=3)

HSP 1 Score: 198.749 bits (504), Expect = 8.600e-57
Identity = 118/277 (42.60%), Postives = 171/277 (61.73%), Query Frame = 1

Query:  274 KPKESLGKLVYAIKYFPESESLRVTVKSGHDLIKLNTGGTSDPYVKVWLKEKPKLKFETKIKRRTRNPVFNEDFTFTVSP-EELPTQTLIFFFYDFDRFSKHEQIGCLMLDLGALDLSKLIEDWAELDQPSSDVNTEIPLGEICMSLKQDPDEEKLFVTILEAKGLRKHDEEDLYDPFLRLSLEEXXXXXXXXXXXXXXXXXPNPYYNEDFEFQLSAELSTKVQLVVTAFNCSNNNIKHSMPIGNIVLGPTITGSGYKHWKEIISNSKRTIVRWHGL 1101
            + ++ LG+L + ++Y   S SL VTV    +L  L+ GGTSDPYVKV+L    K KFETK+ R+T +PVFNE FTF   P  +   +TL+F  +DFDRFSKH+QIG + + L  +DL++ IE+W +L     +   E  LG+IC SL+  P   KL V ILEAK L+K D   L DP++++++ + G  + KKK +  K    NPYYNE F F++  E   K+ LVVT  +   + I  S PIG  +LG   TG+  +HW +++++ +R I +WH L
Sbjct:  188 QSEQKLGRLNFKLEYDFNSNSLAVTVIQAEELPALDMGGTSDPYVKVYLLPDKKKKFETKVHRKTLSPVFNETFTFKSLPYADAMNKTLVFAIFDFDRFSKHDQIGEVKVPLCTIDLAQTIEEWRDLVSVEGEGGQE-KLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIAIMQNGKRLKKKKTSIKKCTL-NPYYNESFSFEVPFEQIQKICLVVTVVD--YDRIGTSEPIGRCILGCMGTGTELRHWSDMLASPRRPIAQWHTL 460

[Close]

BLAST of Synaptotagmin 1 vs. UniProt/SwissProt
Match: sp|Q5R4J5|SYT1_PONAB (Synaptotagmin-1 OS=Pongo abelii OX=9601 GN=SYT1 PE=2 SV=1)

HSP 1 Score: 196.052 bits (497), Expect = 2.413e-56
Identity = 115/271 (42.44%), Postives = 163/271 (60.15%), Query Frame = 1

Query:  289 LGKLVYAIKYFPESESLRVTVKSGHDLIKLNTGGTSDPYVKVWLKEKPKLKFETKIKRRTRNPVFNEDFTFTVSPEELPTQTLIFFFYDFDRFSKHEQIGCLMLDLGALDLSKLIEDWAELDQPSSDVNTEIPLGEICMSLKQDPDEEKLFVTILEAKGLRKHDEEDLYDPFLRLSLEEXXXXXXXXXXXXXXXXXPNPYYNEDFEFQLSAELSTKVQLVVTAFNCSNNNIKHSMPIGNIVLGPTITGSGYKHWKEIISNSKRTIVRWHGL 1101
            LGKL Y++ Y  ++  L V +    +L  L+ GGTSDPYVKV+L    K KFETK+ R+T NPVFNE FTF V   EL  +TL+   YDFDRFSKH+ IG   + +  +D   + E+W +L   S++   +  LG+IC SL+  P   KL V ILEAK L+K D   L DP++++ L + G  + KK+ T  K    NPYYNE F F++  E   KVQ+VVT  +   + I  +  IG + +G   TG+  +HW ++++N +R I +WH L
Sbjct:  140 LGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVTEEWRDLQ--SAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKETTIKKNTL-NPYYNESFSFEVPFEQIQKVQVVVTVLDY--DKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTL 405

HSP 2 Score: 77.0258 bits (188), Expect = 7.477e-14
Identity = 41/113 (36.28%), Postives = 67/113 (59.29%), Query Frame = 1

Query:  259 LKALEKP-KESLGKLVYAIKYFPESESLRVTVKSGHDLIKLNTGGTSDPYVKVWLKEKPKL--KFETKIKRRTRNPVFNEDFTFTVSPEELPTQTLIFFFYDFDRFSKHEQIG 588
            L++ EK  +E LG + ++++Y P +  L V +    +L K++ GG SDPYVK+ L +  K   K ET IK+ T NP +NE F+F V  E++    ++    D+D+  K++ IG
Sbjct:  260 LQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKETTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIG 372

[Close]

BLAST of Synaptotagmin 1 vs. UniProt/SwissProt
Match: sp|P46096|SYT1_MOUSE (Synaptotagmin-1 OS=Mus musculus OX=10090 GN=Syt1 PE=1 SV=1)

HSP 1 Score: 195.282 bits (495), Expect = 4.554e-56
Identity = 116/271 (42.80%), Postives = 163/271 (60.15%), Query Frame = 1

Query:  289 LGKLVYAIKYFPESESLRVTVKSGHDLIKLNTGGTSDPYVKVWLKEKPKLKFETKIKRRTRNPVFNEDFTFTVSPEELPTQTLIFFFYDFDRFSKHEQIGCLMLDLGALDLSKLIEDWAELDQPSSDVNTEIPLGEICMSLKQDPDEEKLFVTILEAKGLRKHDEEDLYDPFLRLSLEEXXXXXXXXXXXXXXXXXPNPYYNEDFEFQLSAELSTKVQLVVTAFNCSNNNIKHSMPIGNIVLGPTITGSGYKHWKEIISNSKRTIVRWHGL 1101
            LGKL Y++ Y  ++  L V +    +L  L+ GGTSDPYVKV+L    K KFETK+ R+T NPVFNE FTF V   EL  +TL+   YDFDRFSKH+ IG   + +  +D   + E+W +L   S++   +  LG+IC SL+  P   KL V ILEAK L+K D   L DP++++ L + G  + KKK T  K    NPYYNE F F++  E   KVQ+VVT  +   + I  +  IG + +G   TG+  +HW ++++N +R I +WH L
Sbjct:  142 LGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVTEEWRDLQ--SAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTL-NPYYNESFSFEVPFEQIQKVQVVVTVLDY--DKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTL 407

HSP 2 Score: 63.1586 bits (152), Expect = 2.123e-9
Identity = 36/113 (31.86%), Postives = 63/113 (55.75%), Query Frame = 1

Query:  259 LKALEKP-KESLGKLVYAIKYFPESESLRVTVKSGHDLIKLNTGGTSDPYVKVWLKEKPKLKFETKIKRRTR--NPVFNEDFTFTVSPEELPTQTLIFFFYDFDRFSKHEQIG 588
            L++ EK  +E LG + ++++Y P +  L V +    +L K++ GG SDPYVK+ L +  K   + K   +    NP +NE F+F V  E++    ++    D+D+  K++ IG
Sbjct:  262 LQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIG 374

[Close]

BLAST of Synaptotagmin 1 vs. UniProt/SwissProt
Match: sp|P21579|SYT1_HUMAN (Synaptotagmin-1 OS=Homo sapiens OX=9606 GN=SYT1 PE=1 SV=1)

HSP 1 Score: 195.282 bits (495), Expect = 4.864e-56
Identity = 116/271 (42.80%), Postives = 163/271 (60.15%), Query Frame = 1

Query:  289 LGKLVYAIKYFPESESLRVTVKSGHDLIKLNTGGTSDPYVKVWLKEKPKLKFETKIKRRTRNPVFNEDFTFTVSPEELPTQTLIFFFYDFDRFSKHEQIGCLMLDLGALDLSKLIEDWAELDQPSSDVNTEIPLGEICMSLKQDPDEEKLFVTILEAKGLRKHDEEDLYDPFLRLSLEEXXXXXXXXXXXXXXXXXPNPYYNEDFEFQLSAELSTKVQLVVTAFNCSNNNIKHSMPIGNIVLGPTITGSGYKHWKEIISNSKRTIVRWHGL 1101
            LGKL Y++ Y  ++  L V +    +L  L+ GGTSDPYVKV+L    K KFETK+ R+T NPVFNE FTF V   EL  +TL+   YDFDRFSKH+ IG   + +  +D   + E+W +L   S++   +  LG+IC SL+  P   KL V ILEAK L+K D   L DP++++ L + G  + KKK T  K    NPYYNE F F++  E   KVQ+VVT  +   + I  +  IG + +G   TG+  +HW ++++N +R I +WH L
Sbjct:  143 LGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVTEEWRDLQ--SAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTL-NPYYNESFSFEVPFEQIQKVQVVVTVLDY--DKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTL 408

HSP 2 Score: 63.1586 bits (152), Expect = 2.167e-9
Identity = 36/113 (31.86%), Postives = 63/113 (55.75%), Query Frame = 1

Query:  259 LKALEKP-KESLGKLVYAIKYFPESESLRVTVKSGHDLIKLNTGGTSDPYVKVWLKEKPKLKFETKIKRRTR--NPVFNEDFTFTVSPEELPTQTLIFFFYDFDRFSKHEQIG 588
            L++ EK  +E LG + ++++Y P +  L V +    +L K++ GG SDPYVK+ L +  K   + K   +    NP +NE F+F V  E++    ++    D+D+  K++ IG
Sbjct:  263 LQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIG 375

[Close]

BLAST of Synaptotagmin 1 vs. TrEMBL
Match: A0A267E333 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig031935g3 PE=4 SV=1)

HSP 1 Score: 239.965 bits (611), Expect = 1.529e-70
Identity = 135/282 (47.87%), Postives = 182/282 (64.54%), Query Frame = 1

Query:  265 ALEKPKESLGKLVYAIKYFPESESLRVTVKSGHDLIKLNTGGTSDPYVKVWLKEKPKLKFETKIKRRTRNPVFNEDFTFTVSPEELPTQTLIFFFYDFDRFSKHEQIGCLMLDLGALDLSKLIEDWAELDQPSSDVNTEIPLGEICMSLKQDPDEEKLFVTILEAKGLRKHDEEDLYDPFLRLSLEEXXXXXXXXXXXXXXXXXPNPYYNEDFEFQLSAELSTKVQLVVTAFNCSNNNIKHSMPIGNIVLGPTITGSGYKHWKEIISNSKRTIVRWHGLVEV 1110
            A EK  E LGKL Y++ Y  +   L V V    DL  ++ GGTSDPYVKV++  + K KFETK+ R+T NPVFNE F F V   ++P++TL+F  YDFDRFSKH+QIG + L LGA+DL++LIE+W ++D P S+ +    LG+IC SL+  P   KL + ILEAK L+K D   L DP+++LSL   G  + KKK T  K    NPYYNE F F++  E   KV L+VT  +   + I  S PIG IVLG T TG+  +HW ++++N +R I +WH L E+
Sbjct:  149 AQEKEVEKLGKLQYSLDYDFQKGELSVGVIQASDLPAMDMGGTSDPYVKVYIMPEKKKKFETKVHRKTLNPVFNETFIFKVPYADVPSKTLVFAVYDFDRFSKHDQIGLIKLPLGAIDLARLIEEWKDIDPPESEDDKSNRLGDICFSLRYVPTAGKLTIVILEAKNLKKMDVGGLSDPYVKLSLMLNGKRIKKKKTTIKKCTL-NPYYNESFSFEVPFEQIQKVSLIVTVVD--YDRIGTSEPIGRIVLGCTATGAELRHWSDMLANPRRPIAQWHTLQEM 427

[Close]

BLAST of Synaptotagmin 1 vs. TrEMBL
Match: A0A267GS86 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig031935g1 PE=4 SV=1)

HSP 1 Score: 239.965 bits (611), Expect = 1.737e-70
Identity = 135/282 (47.87%), Postives = 182/282 (64.54%), Query Frame = 1

Query:  265 ALEKPKESLGKLVYAIKYFPESESLRVTVKSGHDLIKLNTGGTSDPYVKVWLKEKPKLKFETKIKRRTRNPVFNEDFTFTVSPEELPTQTLIFFFYDFDRFSKHEQIGCLMLDLGALDLSKLIEDWAELDQPSSDVNTEIPLGEICMSLKQDPDEEKLFVTILEAKGLRKHDEEDLYDPFLRLSLEEXXXXXXXXXXXXXXXXXPNPYYNEDFEFQLSAELSTKVQLVVTAFNCSNNNIKHSMPIGNIVLGPTITGSGYKHWKEIISNSKRTIVRWHGLVEV 1110
            A EK  E LGKL Y++ Y  +   L V V    DL  ++ GGTSDPYVKV++  + K KFETK+ R+T NPVFNE F F V   ++P++TL+F  YDFDRFSKH+QIG + L LGA+DL++LIE+W ++D P S+ +    LG+IC SL+  P   KL + ILEAK L+K D   L DP+++LSL   G  + KKK T  K    NPYYNE F F++  E   KV L+VT  +   + I  S PIG IVLG T TG+  +HW ++++N +R I +WH L E+
Sbjct:  149 AQEKEVEKLGKLQYSLDYDFQKGELSVGVIQASDLPAMDMGGTSDPYVKVYIMPEKKKKFETKVHRKTLNPVFNETFIFKVPYADVPSKTLVFAVYDFDRFSKHDQIGLIKLPLGAIDLARLIEEWKDIDPPESEDDKSNRLGDICFSLRYVPTAGKLTIVILEAKNLKKMDVGGLSDPYVKLSLMLNGKRIKKKKTTIKKCTL-NPYYNESFSFEVPFEQIQKVSLIVTVVD--YDRIGTSEPIGRIVLGCTATGAELRHWSDMLANPRRPIAQWHTLQEM 427

[Close]

BLAST of Synaptotagmin 1 vs. TrEMBL
Match: A0A267E6V1 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig031935g2 PE=4 SV=1)

HSP 1 Score: 238.424 bits (607), Expect = 6.572e-70
Identity = 134/280 (47.86%), Postives = 181/280 (64.64%), Query Frame = 1

Query:  271 EKPKESLGKLVYAIKYFPESESLRVTVKSGHDLIKLNTGGTSDPYVKVWLKEKPKLKFETKIKRRTRNPVFNEDFTFTVSPEELPTQTLIFFFYDFDRFSKHEQIGCLMLDLGALDLSKLIEDWAELDQPSSDVNTEIPLGEICMSLKQDPDEEKLFVTILEAKGLRKHDEEDLYDPFLRLSLEEXXXXXXXXXXXXXXXXXPNPYYNEDFEFQLSAELSTKVQLVVTAFNCSNNNIKHSMPIGNIVLGPTITGSGYKHWKEIISNSKRTIVRWHGLVEV 1110
            EK  E LGKL Y++ Y  +   L V V    DL  ++ GGTSDPYVKV++  + K KFETK+ R+T NPVFNE F F V   ++P++TL+F  YDFDRFSKH+QIG + L LGA+DL++LIE+W ++D P S+ +    LG+IC SL+  P   KL + ILEAK L+K D   L DP+++LSL   G  + KKK T  K    NPYYNE F F++  E   KV L+VT  +   + I  S PIG IVLG T TG+  +HW ++++N +R I +WH L E+
Sbjct:  151 EKEVEKLGKLQYSLDYDFQKGELSVGVIQASDLPAMDMGGTSDPYVKVYILPEKKKKFETKVHRKTLNPVFNETFIFKVPYADVPSKTLVFAVYDFDRFSKHDQIGLIKLPLGAIDLARLIEEWKDIDPPESEDDKSNRLGDICFSLRYVPTAGKLTIVILEAKNLKKMDVGGLSDPYVKLSLMLNGKRIKKKKTTIKKCTL-NPYYNESFSFEVPFEQIQKVSLIVTVVD--YDRIGTSEPIGRIVLGCTATGAELRHWSDMLANPRRPIAQWHTLQEM 427

[Close]

BLAST of Synaptotagmin 1 vs. TrEMBL
Match: A0A1D2ML67 (Synaptotagmin 1 (Fragment) OS=Orchesella cincta OX=48709 GN=Ocin01_12882 PE=4 SV=1)

HSP 1 Score: 223.402 bits (568), Expect = 1.375e-65
Identity = 128/283 (45.23%), Postives = 176/283 (62.19%), Query Frame = 1

Query:  277 PKESLGKLVYAIKYFPESESLRVTVKSGHDLIKLNTGGTSDPYVKVWLKEKPKLKFETKIKRRTRNPVFNEDFTFTVSPEELPTQTLIFFFYDFDRFSKHEQIGCLMLDLGALDLSKLIEDWAELDQPSSDVNTEIPLGEICMSLKQDPDEEKLFVTILEAKGLRKHDEEDLYDPFLRLSLEEXXXXXXXXXXXXXXXXXPNPYYNEDFEFQLSAELSTKVQLVVTAFNCSNNNIKHSMPIGNIVLGPTITGSGYKHWKEIISNSKRTIVRWHGLVEVVDNKK 1125
            P + LGKL Y ++Y   + +L+VTV    DL  L+ GGTSDPYVKV+L    K KFETK+ R+T NP+FNE F F +   +L  +TL+F  +DFDRFSKH+QIG + + L  LDL++ IEDW EL     +   E  LG+IC SL+  P   KL V ILEAK L+K D   L DP+++++L + G  + KKK +  K    NPYYNE F F++  E   KV LV+T  +   + I  S PIG +VLG   TG+  +HW +++++ +R I +WH L E  D KK
Sbjct:   32 PVQKLGKLQYRLEYDFNANNLQVTVIQAEDLPALDMGGTSDPYVKVYLLPDKKKKFETKVHRKTLNPIFNETFNFKLPYSDLMAKTLVFAIFDFDRFSKHDQIGEVKIPLCQLDLAQTIEDWKELQSVEGEGGQENKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIALMQNGKRLKKKKTSIKKCTL-NPYYNESFTFEVPFEQIQKVNLVITVVDY--DRIGTSEPIGKVVLGCNATGTELRHWSDMLASPRRPIAQWHTLKEPDDEKK 311

[Close]

BLAST of Synaptotagmin 1 vs. TrEMBL
Match: A0A267EMR3 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig002345g1 PE=4 SV=1)

HSP 1 Score: 226.483 bits (576), Expect = 1.669e-65
Identity = 126/274 (45.99%), Postives = 174/274 (63.50%), Query Frame = 1

Query:  289 LGKLVYAIKYFPESESLRVTVKSGHDLIKLNTGGTSDPYVKVWLKEKPKLKFETKIKRRTRNPVFNEDFTFTVSPEELPTQTLIFFFYDFDRFSKHEQIGCLMLDLGALDLSKLIEDWAELDQPSSDVNTEIPLGEICMSLKQDPDEEKLFVTILEAKGLRKHDEEDLYDPFLRLSLEEXXXXXXXXXXXXXXXXXPNPYYNEDFEFQLSAELSTKVQLVVTAFNCSNNNIKHSMPIGNIVLGPTITGSGYKHWKEIISNSKRTIVRWHGLVEV 1110
            LGKL Y++ Y  +   L V V    DL  ++ GGTSDPYVK ++    K KFETK+ R+T NPVFNE F F V   ++P++TL+F  YDFDRFSKH+QIG + L LG +DL+++IE+W ++D P S+ +    LG+IC SL+  P   KL + ILEAK L+K D   L DP+++LSL   G  + KKK T  K    NPYYNE F F++  E   KV L+VT  +   + I  S PIG +VLG T T +  +HW ++++N +R I +WH L E+
Sbjct:  142 LGKLQYSLDYDFQKGELSVGVIQAADLPAMDMGGTSDPYVKTYILPDKKKKFETKVHRKTLNPVFNETFVFKVPYADVPSKTLVFAIYDFDRFSKHDQIGLIKLPLGCMDLARVIEEWKDVDPPESEDDKSNKLGDICFSLRYVPTAGKLTIVILEAKNLKKMDVGGLSDPYVKLSLMMNGKRLKKKKTTIKKCTL-NPYYNESFTFEVPFEQIQKVTLIVTVVD--YDRIGTSEPIGRVVLGCTATQAELRHWSDMLANPRRPIAQWHTLQEM 412

[Close]

BLAST of Synaptotagmin 1 vs. Ensembl Cavefish
Match: ENSAMXT00000017640.2 (synaptotagmin-1-like [Source:NCBI gene;Acc:103035847])

HSP 1 Score: 201.445 bits (511), Expect = 2.539e-59
Identity = 115/273 (42.12%), Postives = 171/273 (62.64%), Query Frame = 1

Query:  292 GKLVYAIKYFPESESLRVTVKSGHDLIKLNTGGTSDPYVKVWLKEKPKLKFETKIKRRTRNPVFNEDFTFTVSPEELPTQTLIFFFYDFDRFSKHEQIGCLMLDLGALDLSKLIEDWAELDQPSSDVNTEIPLGEICMSLKQDPDEEKLFVTILEAKGLRKHDEEDLYDPFLRLSLEEXXXXXXXXXXXXXXXXXPNPYYNEDFEFQLSAELSTKVQLVVTAFNCSNNNIKHSMPIGNIVLGPTITGSGYKHWKEIISNSKRTIVRWHGLVEV 1110
            GKL+Y+++Y      + V +K   +L+ ++ GGTSDPYVKV++       FETK+ R+T NPVFNE F + +S +EL   TL+   YDF+RFSKH+ IG L L+L A+D + +IE+W +L +PS   + +  LGEIC SL+  P   KL V ILEAK L+K D     DP++++ L        KKK T++KK T NPY+NE F F +S E   KVQLV++ ++  ++ +  +  IG I LG   TG+  +HW +++SN +R + +WH L+  
Sbjct:  137 GKLLYSLEYNAARSEMAVGIKEAAELMAMDHGGTSDPYVKVYVLPSKSKTFETKVFRKTLNPVFNESFKYQISQKELGESTLVIQVYDFNRFSKHDVIGELRLELSAVDWNHVIEEWRDLSKPSK--HEQEHLGEICFSLRYVPTASKLTVVILEAKNLKKMDHGGYSDPYVKVQL-ILDKRKWKKKKTSVKKQTLNPYFNESFTFDVSFEQIQKVQLVISVWD--HDKMSRNDAIGKIFLGCDATGNQLRHWADMLSNPRRPVAQWHTLLSA 404

HSP 2 Score: 73.9442 bits (180), Expect = 7.415e-14
Identity = 47/136 (34.56%), Postives = 78/136 (57.35%), Query Frame = 1

Query:  262 KALEKP----KESLGKLVYAIKYFPESESLRVTVKSGHDLIKLNTGGTSDPYVKVW--LKEKPKLKFETKIKRRTRNPVFNEDFTFTVSPEELPTQTLIFFFYDFDRFSKHEQIGCLMLDLGALDLSKLIEDWAEL 651
            + L KP    +E LG++ ++++Y P +  L V +    +L K++ GG SDPYVKV   L ++   K +T +K++T NP FNE FTF VS E++    L+   +D D+ S+++ IG + L   A      +  WA++
Sbjct:  254 RDLSKPSKHEQEHLGEICFSLRYVPTASKLTVVILEAKNLKKMDHGGYSDPYVKVQLILDKRKWKKKKTSVKKQTLNPYFNESFTFDVSFEQIQKVQLVISVWDHDKMSRNDAIGKIFLGCDA--TGNQLRHWADM 387

[Close]

BLAST of Synaptotagmin 1 vs. Ensembl Cavefish
Match: syt1b (synaptotagmin Ib [Source:ZFIN;Acc:ZDB-GENE-060503-166])

HSP 1 Score: 195.667 bits (496), Expect = 4.481e-57
Identity = 115/279 (41.22%), Postives = 167/279 (59.86%), Query Frame = 1

Query:  271 EKPKES--LGKLVYAIKYFPESESLRVTVKSGHDLIKLNTGGTSDPYVKVWLKEKPKLKFETKIKRRTRNPVFNEDFTFTVSPEELPTQTLIFFFYDFDRFSKHEQIGCLMLDLGALDLSKLIEDWAELDQPSSDVNTEIPLGEICMSLKQDPDEEKLFVTILEAKGLRKHDEEDLYDPFLRLSLEEXXXXXXXXXXXXXXXXXPNPYYNEDFEFQLSAELSTKVQLVVTAFNCSNNNIKHSMPIGNIVLGPTITGSGYKHWKEIISNSKRTIVRWHGL 1101
            E PKE   LGKL +++ Y     SL V +    DL  ++  GTSDPYVK++L    K KFETK+ R+T NP FNE FTF V   EL  +TL+   YDFDRFSKH+ IG + + +  +D S++ E+W  L +   +   +  LG+IC+SL+  P   KL V +LEAK L+K D   L DP++++ L + G  + KKK T  K    NPYYNE F F++ +E   KVQ+VVT  +   + I  +  IG + +G   +G+  +HW ++++N +R I +WH L
Sbjct:  133 EGPKEEQKLGKLQFSLDYHFTDGSLIVGIIQAEDLAAMDMSGTSDPYVKLYLLPDKKKKFETKVHRKTLNPTFNEHFTFKVPYSELGGKTLVMTVYDFDRFSKHDAIGDVRVQMNKVDFSQVTEEWRVLQKAEKEEQEK--LGDICLSLRYVPTAGKLTVVVLEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKHTL-NPYYNESFSFEVPSEQIQKVQVVVTVLD--YDKIGKNDAIGKVFMGLHSSGTEQRHWADMLANPRRPIAQWHAL 406

HSP 2 Score: 66.2402 bits (160), Expect = 2.640e-11
Identity = 44/155 (28.39%), Postives = 77/155 (49.68%), Query Frame = 1

Query:  262 KALEKPKESLGKLVYAIKYFPESESLRVTVKSGHDLIKLNTGGTSDPYVKVWLKEKPKLKFETKIKRRTR--NPVFNEDFTFTVSPEELPTQTLIFFFYDFDRFSKHEQIGCLMLDLGA------------LDLSKLIEDWAELDQPSSDVNTEI 684
            KA ++ +E LG +  +++Y P +  L V V    +L K++ GG SDPYVK+ L +  K   + K   +    NP +NE F+F V  E++    ++    D+D+  K++ IG + + L +             +  + I  W  L +P  DV+ E+
Sbjct:  263 KAEKEEQEKLGDICLSLRYVPTAGKLTVVVLEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKHTLNPYYNESFSFEVPSEQIQKVQVVVTVLDYDKIGKNDAIGKVFMGLHSSGTEQRHWADMLANPRRPIAQWHAL-KPEEDVDAEL 416

[Close]

BLAST of Synaptotagmin 1 vs. Ensembl Cavefish
Match: syt1b (synaptotagmin Ib [Source:ZFIN;Acc:ZDB-GENE-060503-166])

HSP 1 Score: 195.282 bits (495), Expect = 4.778e-57
Identity = 115/279 (41.22%), Postives = 167/279 (59.86%), Query Frame = 1

Query:  271 EKPKES--LGKLVYAIKYFPESESLRVTVKSGHDLIKLNTGGTSDPYVKVWLKEKPKLKFETKIKRRTRNPVFNEDFTFTVSPEELPTQTLIFFFYDFDRFSKHEQIGCLMLDLGALDLSKLIEDWAELDQPSSDVNTEIPLGEICMSLKQDPDEEKLFVTILEAKGLRKHDEEDLYDPFLRLSLEEXXXXXXXXXXXXXXXXXPNPYYNEDFEFQLSAELSTKVQLVVTAFNCSNNNIKHSMPIGNIVLGPTITGSGYKHWKEIISNSKRTIVRWHGL 1101
            E PKE   LGKL +++ Y     SL V +    DL  ++  GTSDPYVK++L    K KFETK+ R+T NP FNE FTF V   EL  +TL+   YDFDRFSKH+ IG + + +  +D S++ E+W  L +   +   +  LG+IC+SL+  P   KL V +LEAK L+K D   L DP++++ L + G  + KKK T  K    NPYYNE F F++ +E   KVQ+VVT  +   + I  +  IG + +G   +G+  +HW ++++N +R I +WH L
Sbjct:  130 EGPKEEQKLGKLQFSLDYHFTDGSLIVGIIQAEDLAAMDMSGTSDPYVKLYLLPDKKKKFETKVHRKTLNPTFNEHFTFKVPYSELGGKTLVMTVYDFDRFSKHDAIGDVRVQMNKVDFSQVTEEWRVLQKAEKEEQEK--LGDICLSLRYVPTAGKLTVVVLEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKHTL-NPYYNESFSFEVPSEQIQKVQVVVTVLDY--DKIGKNDAIGKVFMGLHSSGTEQRHWADMLANPRRPIAQWHAL 403

HSP 2 Score: 66.2402 bits (160), Expect = 2.590e-11
Identity = 44/155 (28.39%), Postives = 77/155 (49.68%), Query Frame = 1

Query:  262 KALEKPKESLGKLVYAIKYFPESESLRVTVKSGHDLIKLNTGGTSDPYVKVWLKEKPKLKFETKIKRRTR--NPVFNEDFTFTVSPEELPTQTLIFFFYDFDRFSKHEQIGCLMLDLGA------------LDLSKLIEDWAELDQPSSDVNTEI 684
            KA ++ +E LG +  +++Y P +  L V V    +L K++ GG SDPYVK+ L +  K   + K   +    NP +NE F+F V  E++    ++    D+D+  K++ IG + + L +             +  + I  W  L +P  DV+ E+
Sbjct:  260 KAEKEEQEKLGDICLSLRYVPTAGKLTVVVLEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKHTLNPYYNESFSFEVPSEQIQKVQVVVTVLDYDKIGKNDAIGKVFMGLHSSGTEQRHWADMLANPRRPIAQWHAL-KPEEDVDAEL 413

[Close]

BLAST of Synaptotagmin 1 vs. Ensembl Cavefish
Match: syt1a (synaptotagmin 1 [Source:NCBI gene;Acc:103044539])

HSP 1 Score: 194.512 bits (493), Expect = 1.090e-56
Identity = 116/280 (41.43%), Postives = 167/280 (59.64%), Query Frame = 1

Query:  262 KALEKPKESLGKLVYAIKYFPESESLRVTVKSGHDLIKLNTGGTSDPYVKVWLKEKPKLKFETKIKRRTRNPVFNEDFTFTVSPEELPTQTLIFFFYDFDRFSKHEQIGCLMLDLGALDLSKLIEDWAELDQPSSDVNTEIPLGEICMSLKQDPDEEKLFVTILEAKGLRKHDEEDLYDPFLRLSLEEXXXXXXXXXXXXXXXXXPNPYYNEDFEFQLSAELSTKVQLVVTAFNCSNNNIKHSMPIGNIVLGPTITGSGYKHWKEIISNSKRTIVRWHGL 1101
            +A  K +E LGKL Y++ Y     +L V +    +L  ++ GGTSDPYVKV+L    K KFETK+ R+T NP FNE FTF V   EL  +TL+   YDFDRFSKH+ IG + + +  +D S + E+W +L   S++   +  LG+IC SL+  P   KL V ILEAK L+K D   L DP+ ++ L + G  + KKK T  K    NPYYNE F F++  E   KVQ+V+T  +   + I  +  IG + +G   +G+  +HW ++++N +R I +WH L
Sbjct:  127 EAEPKEQEKLGKLQYSLDYNFTENTLIVGIIQAAELPAMDMGGTSDPYVKVYLLPDKKKKFETKVHRKTLNPTFNEQFTFKVPYTELGGKTLVMTVYDFDRFSKHDAIGDVKVPMNKVDFSHVTEEWRDLQ--SAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYAKIHLMQNGKRLKKKKTTIKKNTL-NPYYNESFSFEVPFEQIQKVQIVITVLDY--DKIGKNDAIGKVFVGLNSSGTELRHWSDMLANPRRPIAQWHVL 401

[Close]

BLAST of Synaptotagmin 1 vs. Ensembl Cavefish
Match: syt1a (synaptotagmin 1 [Source:NCBI gene;Acc:103044539])

HSP 1 Score: 194.126 bits (492), Expect = 1.415e-56
Identity = 116/280 (41.43%), Postives = 167/280 (59.64%), Query Frame = 1

Query:  262 KALEKPKESLGKLVYAIKYFPESESLRVTVKSGHDLIKLNTGGTSDPYVKVWLKEKPKLKFETKIKRRTRNPVFNEDFTFTVSPEELPTQTLIFFFYDFDRFSKHEQIGCLMLDLGALDLSKLIEDWAELDQPSSDVNTEIPLGEICMSLKQDPDEEKLFVTILEAKGLRKHDEEDLYDPFLRLSLEEXXXXXXXXXXXXXXXXXPNPYYNEDFEFQLSAELSTKVQLVVTAFNCSNNNIKHSMPIGNIVLGPTITGSGYKHWKEIISNSKRTIVRWHGL 1101
            +A  K +E LGKL Y++ Y     +L V +    +L  ++ GGTSDPYVKV+L    K KFETK+ R+T NP FNE FTF V   EL  +TL+   YDFDRFSKH+ IG + + +  +D S + E+W +L   S++   +  LG+IC SL+  P   KL V ILEAK L+K D   L DP+ ++ L + G  + KKK T  K    NPYYNE F F++  E   KVQ+V+T  +   + I  +  IG + +G   +G+  +HW ++++N +R I +WH L
Sbjct:  130 EAEPKEQEKLGKLQYSLDYNFTENTLIVGIIQAAELPAMDMGGTSDPYVKVYLLPDKKKKFETKVHRKTLNPTFNEQFTFKVPYTELGGKTLVMTVYDFDRFSKHDAIGDVKVPMNKVDFSHVTEEWRDLQ--SAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYAKIHLMQNGKRLKKKKTTIKKNTL-NPYYNESFSFEVPFEQIQKVQIVITVLDY--DKIGKNDAIGKVFVGLNSSGTELRHWSDMLANPRRPIAQWHVL 404

[Close]

BLAST of Synaptotagmin 1 vs. Ensembl Sea Lamprey
Match: syt2a (synaptotagmin IIa [Source:ZFIN;Acc:ZDB-GENE-060503-315])

HSP 1 Score: 114.39 bits (285), Expect = 8.604e-30
Identity = 58/121 (47.93%), Postives = 79/121 (65.29%), Query Frame = 1

Query:  289 LGKLVYAIKYFPESESLRVTVKSGHDLIKLNTGGTSDPYVKVWLKEKPKLKFETKIKRRTRNPVFNEDFTFTVSPEELPTQTLIFFFYDFDRFSKHEQIGCLMLDLGALDLSKLIEDWAEL 651
            LGKL ++I Y  ++  L V V    +L  L+ GGTSDPYVK++L    K K+ETK+ R+T NPVFNE F F V   EL  +TL+   YDFDRFSKH+ IG + + +  +DL  +IE+W +L
Sbjct:   80 LGKLQFSIDYDFQNNQLTVGVIQAAELPALDMGGTSDPYVKLFLMPDKKKKYETKVHRKTLNPVFNESFVFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEVKVPMNTIDLGHVIEEWRDL 200

[Close]

BLAST of Synaptotagmin 1 vs. Ensembl Sea Lamprey
Match: SYT5 (synaptotagmin 5 [Source:HGNC Symbol;Acc:HGNC:11513])

HSP 1 Score: 114.39 bits (285), Expect = 8.966e-30
Identity = 55/128 (42.97%), Postives = 81/128 (63.28%), Query Frame = 1

Query:  286 SLGKLVYAIKYFPESESLRVTVKSGHDLIKLNTGGTSDPYVKVWLKEKPKLKFETKIKRRTRNPVFNEDFTFTVSPEELPTQTLIFFFYDFDRFSKHEQIGCLMLDLGALDLSKLIEDWAELDQPSSD 669
            +LG+L +++ Y  ++    V +    DL  ++ GG SDPYV+V+L    K KFET + R+T NP+F E FTFTV  EEL  + L+   YDFDRFS+H+ IG L + L ++DLS  +E+W +L +   D
Sbjct:   78 TLGRLQFSLDYNLKTSQFTVGILQATDLAAMDIGGMSDPYVRVYLLPHKKKKFETSVHRKTLNPIFEEKFTFTVPFEELVERVLVMVVYDFDRFSRHDIIGELRIPLSSVDLSHSVEEWRDLQKTEKD 205

[Close]

BLAST of Synaptotagmin 1 vs. Ensembl Sea Lamprey
Match: syt2a (synaptotagmin IIa [Source:ZFIN;Acc:ZDB-GENE-060503-315])

HSP 1 Score: 114.775 bits (286), Expect = 1.192e-29
Identity = 58/121 (47.93%), Postives = 79/121 (65.29%), Query Frame = 1

Query:  289 LGKLVYAIKYFPESESLRVTVKSGHDLIKLNTGGTSDPYVKVWLKEKPKLKFETKIKRRTRNPVFNEDFTFTVSPEELPTQTLIFFFYDFDRFSKHEQIGCLMLDLGALDLSKLIEDWAEL 651
            LGKL ++I Y  ++  L V V    +L  L+ GGTSDPYVK++L    K K+ETK+ R+T NPVFNE F F V   EL  +TL+   YDFDRFSKH+ IG + + +  +DL  +IE+W +L
Sbjct:   97 LGKLQFSIDYDFQNNQLTVGVIQAAELPALDMGGTSDPYVKLFLMPDKKKKYETKVHRKTLNPVFNESFVFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEVKVPMNTIDLGHVIEEWRDL 217

[Close]

BLAST of Synaptotagmin 1 vs. Ensembl Sea Lamprey
Match: SYT6 (synaptotagmin 6 [Source:HGNC Symbol;Acc:HGNC:18638])

HSP 1 Score: 95.9005 bits (237), Expect = 6.930e-23
Identity = 54/123 (43.90%), Postives = 74/123 (60.16%), Query Frame = 1

Query:  292 GKLVYAIKYFPESESLRVTVKSGHDLIKLNTGGTSDPYVKVWLKEKPKLKFETKIKRRTRNPVFNEDFTFTVSPEELPTQTLIFFFYDFDRFSKHEQIGCLMLD--LGALDLSKLIEDWAELD 654
            GKL +A+ Y  E E L V V    +L   +  GTSDPYVK++L    K K++TK+ R+T NPVF E F F V   ELP + L F  YDFDRFS+H+ IG +++D      DLS+    W +++
Sbjct:  114 GKLNFALHYDYEMEQLLVRVCRAAELPAKDFSGTSDPYVKIYLLPDRKRKYQTKVHRKTLNPVFEETFQFFVPYAELPARRLHFSVYDFDRFSRHDTIGQVVVDNLFEESDLSRETSLWRDIE 236

[Close]

BLAST of Synaptotagmin 1 vs. Ensembl Sea Lamprey
Match: SYT6 (synaptotagmin 6 [Source:HGNC Symbol;Acc:HGNC:18638])

HSP 1 Score: 97.4413 bits (241), Expect = 7.505e-23
Identity = 51/123 (41.46%), Postives = 77/123 (62.60%), Query Frame = 1

Query:  292 GKLVYAIKYFPESESLRVTVKSGHDLIKLNTGGTSDPYVKVWLKEKPKLKFETKIKRRTRNPVFNEDFTFTVSPEELPTQTLIFFFYDFDRFSKHEQIGCLMLD--LGALDLSKLIEDWAELD 654
            G++ + ++Y  E E L V +    DL   +  GTSDPYVK++L  + K K++TK+ R+T NPVF+E F F V   EL ++ L F  YDFDRFS+H+ IG +++D  L A D S+    W +++
Sbjct:  185 GRINFQVRYDYEGEQLVVKINKAVDLPAKDFSGTSDPYVKIYLLPERKRKYQTKVHRKTLNPVFDETFQFGVPYSELASRRLHFSVYDFDRFSRHDIIGTVLVDNLLEATDHSRETSIWRDIE 307

[Close]

BLAST of Synaptotagmin 1 vs. Ensembl Yeast
Match: TCB2 (ER protein involved in ER-plasma membrane tethering; one of 6 proteins (Ist2p, Scs2p, Scs22p, Tcb1p, Tcb2p, Tcb3p) that connect ER to plasma membrane (PM) and regulate PM phosphatidylinositol-4-phosphate (PI4P) levels by controlling access of Sac1p phosphatase to its substrate PI4P in the PM; contains 3 calcium and lipid binding domains; mRNA is targeted to bud; TCB2 has a paralog, TCB1, that arose from the whole genome duplication [Source:SGD;Acc:S000005031])

HSP 1 Score: 55.8398 bits (133), Expect = 9.213e-9
Identity = 43/147 (29.25%), Postives = 65/147 (44.22%), Query Frame = 1

Query:  292 GKLVYAIKYFP-------------ESESLRVTVKSGHDLIKLNTGGTSDPYVKVWLKEKPKLK-FETKIKRRTRNPVFNEDFTFTVSPEELPTQTLIFFFYDFDRFSKHEQIGCLMLDLGALDLSKLIEDWAELDQPSSDVNTEIPL 690
             KL+  + +FP              S  L++T KS  +LI +N  G SDPYV+ +L EK     F+T ++++T NP +NE  T  VS        L     D++  + +  IG  ++ L  +D             P SD    IPL
Sbjct:  957 AKLLVQVSWFPVTATELPQSDLITNSGDLKITAKSAENLIGVNKNGYSDPYVEFFLNEKSTSPFFKTAVQKKTLNPTWNESKTIEVSNR--VNDYLTINVKDYESTNSNRSIGKAVVPLSTID-------------PESDTTFNIPL 1088

[Close]

BLAST of Synaptotagmin 1 vs. Ensembl Yeast
Match: TCB3 (Cortical ER protein involved in ER-plasma membrane tethering; one of 6 proteins (Ist2p, Scs2p, Scs22p, Tcb1p, Tcb2p, Tcb3p) that connect ER to the plasma membrane (PM) and regulate PM phosphatidylinositol-4-phosphate (PI4P) levels by controlling access of Sac1p phosphatase to its substrate PI4P in the PM; localized to the bud via specific mRNA transport; non-tagged protein detected in a phosphorylated state in mitochondria; C-termini of Tcb1p, Tcb2p and Tcb3p interact [Source:SGD;Acc:S000004537])

HSP 1 Score: 55.0694 bits (131), Expect = 1.739e-8
Identity = 34/109 (31.19%), Postives = 58/109 (53.21%), Query Frame = 1

Query:  319 FPESES------LRVTVKSGHDLIKLNTGGTSDPYVKVWLKEKPKLKFETKIKRRTRNPVFNEDFTFTVSPEELPTQTLIFFFYDFDRFSKHEQIGCLMLDLGALDLSK 627
             P SES      L + + SGH L   +  G SDP+V +++ +K    F++ IK++T +PV+NED    +         +IF   D+DR   ++ +G   LD+ +L++ K
Sbjct: 1124 LPSSESVEDTGYLNIKLISGHGLKSADRNGYSDPFVHIFVNDKK--VFKSNIKKKTLDPVWNEDAKIPILSRS--KNQVIFNVLDWDRAGDNDDLGQASLDVSSLEVGK 1228

[Close]

BLAST of Synaptotagmin 1 vs. Ensembl Yeast
Match: TCB1 (Lipid-binding ER protein involved in ER-plasma membrane tethering; one of 6 proteins (Ist2p, Scs2p, Scs22p, Tcb1p, Tcb2p, Tcb3p) that connect ER to plasma membrane and regulate PI4P levels by controlling access of Sac1p phosphatase to its substrate PI4P in PM; contains 3 calcium and lipid binding domains; non-tagged protein also localizes to mitochondria; C-termini of Tcb1p, Tcb2p and Tcb3p interact; TCB1 has a paralog, TCB2, that arose from the whole genome duplication [Source:SGD;Acc:S000005612])

HSP 1 Score: 47.3654 bits (111), Expect = 3.974e-6
Identity = 36/139 (25.90%), Postives = 61/139 (43.88%), Query Frame = 1

Query:  283 ESLGKLVYAIKYFP-------------ESESLRVTVKSGHDLIKLNTGGTSDPYVKVWLKEKPKLKFETKIKRRTRNPVFNEDFTFTVSPEELPTQTLIFFFYDFDRFSKHEQIGCLMLDLGALDLSKLIEDWAELDQP 660
            E   KL+  I +FP              S  L +  +S  +LI  +  G SDPY+K ++  +    ++TK+ ++T NP +N++ T  ++        L     D+D  S  + IG   + L  +     +E   ELD P
Sbjct:  963 EGSAKLMLQISWFPIDTKQLPANDLITNSGDLTIMSRSAENLIASDLNGYSDPYLKYYINNEEDCAYKTKVVKKTLNPKWNDEGTIQINNR--LNDVLRIKVMDWDSTSADDTIGTAEIPLNKVK----VEGTTELDVP 1095

[Close]

BLAST of Synaptotagmin 1 vs. Ensembl Nematostella
Match: EDO31746 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SX17])

HSP 1 Score: 159.458 bits (402), Expect = 1.266e-44
Identity = 96/275 (34.91%), Postives = 157/275 (57.09%), Query Frame = 1

Query:  289 LGKLVYAIKYFPESESLRVTVKSGHDLIKLNTGGTSDPYVKVWLKEKPKLKFETKIKRRTRNPVFNEDFTFTVSP-EELPTQTLIFFFYDFDRFSKHEQIGCLMLDLGALDLSKLIEDWAELDQPSSD---VNTEIPLGEICMSLKQDPDEEKLFVTILEAKGLRKHDEEDLYDPFLRLSLEEXXXXXXXXXXXXXXXXXPNPYYNEDFEFQLSAELSTKVQLVVTAFNCSNNNIKHSMPIGNIVLGPTITGSGYKHWKEIISNSKRTIVRWHGL 1101
            +G++ + + Y     +L V +    D+   +  G+SDPYVK+ L    K K+ETK+ R+T NPVFNE F F   P  E+  + L+   +DFDRFS+H+ IG   L L  +DL+  I +W  L  PS      +++  LG+IC SL+  P   KL +TI+EAK L+  D     DP+++++L + G  + KKK T  K+   NPYYNE F F ++ E   +  L+++  +   + +  S  IG  V+G   +G+  +HW +++++ +R++ +WH L
Sbjct:   84 IGRINFTLDYSFTDNTLTVGIIRAEDIPAKDFSGSSDPYVKIMLLPDKKKKYETKVHRKTLNPVFNEQFVFKNIPYSEITNRILLMELFDFDRFSRHDLIGEARLPLIDVDLASNINEWRVLTPPSGSGGAGHSKSDLGDICFSLRYVPSSGKLQITIVEAKSLKSMDLTGYSDPYVKIALVQEGRKIKKKKTTVKKRTL-NPYYNETFTFTVAFEKIEQTSLIISVLDY--DRVGKSEMIGKCVVGELSSGADLRHWADMLASPRRSVAQWHTL 355

HSP 2 Score: 72.7886 bits (177), Expect = 4.963e-14
Identity = 43/127 (33.86%), Postives = 70/127 (55.12%), Query Frame = 1

Query:  280 KESLGKLVYAIKYFPESESLRVTVKSGHDLIKLNTGGTSDPYVKVWLKEKPKLKFETKIKRRTR--NPVFNEDFTFTVSPEELPTQTLIFFFYDFDRFSKHEQIG-CLMLDLGALDLSKLIEDWAEL 651
            K  LG + ++++Y P S  L++T+     L  ++  G SDPYVK+ L ++ +   + K   + R  NP +NE FTFTV+ E++   +LI    D+DR  K E IG C+   +G L     +  WA++
Sbjct:  218 KSDLGDICFSLRYVPSSGKLQITIVEAKSLKSMDLTGYSDPYVKIALVQEGRKIKKKKTTVKKRTLNPYYNETFTFTVAFEKIEQTSLIISVLDYDRVGKSEMIGKCV---VGELSSGADLRHWADM 341

[Close]

BLAST of Synaptotagmin 1 vs. Ensembl Nematostella
Match: EDO43704 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RXY7])

HSP 1 Score: 130.954 bits (328), Expect = 5.816e-35
Identity = 84/279 (30.11%), Postives = 149/279 (53.41%), Query Frame = 1

Query:  283 ESLGKLVYAIKYFPESESLRVTVKSGHDLIKLNTGGTSDPYVKVWLKEKPKLKFETKIKRRTRNPVFNEDFTFTVSPE-ELPTQTLIFFFYDFDRFSKHEQIGCLMLDLGALDLSKLIEDWAELDQPSSDVNTEIPLGEICMSLKQDPDEEKLFVTILEAKGLRKHDEEDLYDPFLRLSLEEXXXXXXXXXXXXXXXXXPNPYYNEDFEFQLSAELSTKVQLVVTAFNCSN-NNIKHSMPIGNIVLGPTITGSGYKHWKEIISNSKRTIVRWHGLVEVV 1113
            E LGK+ +++ Y+     L + V     L   +  GTSDP+VK+ L    K K ET++KR+  NPV+NE FTF   P  +L  +TL     D+DRFS+++ IG + + L  +DL  +   + +   P       +PLG++ +SL   P   ++ V +++A  L+  D     DP++++ +      + KKK T  ++   +P +NE F F +  +   K++ +   FN  + + I  +  IG ++LG   TGS  +HW E+++N ++ + +WH L + +
Sbjct:    1 EQLGKIFFSLTYYSSDSVLTLKVLKAQGLPAKDFSGTSDPFVKIMLLPDKKHKLETRVKRKNLNPVWNEVFTFEGFPHNKLMGKTLYMQVLDYDRFSRNDPIGEVEIPLENIDLGPVTLTFTKDLLPCK--KDRVPLGDLLVSLMYQPTNNRIIVVVMKANKLKAMDLTGSSDPYVKMYIMHKDRRLDKKKTTIKRRTR-DPVWNESFIFDVPLD---KIRDLTFVFNVMDYDRITQNELIGQVILGYRTTGSSLRHWTEMMNNPRKPVAQWHRLQDAL 273

HSP 2 Score: 77.411 bits (189), Expect = 5.469e-16
Identity = 44/129 (34.11%), Postives = 74/129 (57.36%), Query Frame = 1

Query:  271 EKPKESLGKLVYAIKYFPESESLRVTVKSGHDLIKLNTGGTSDPYVKVWLKEKPKL--KFETKIKRRTRNPVFNEDFTFTVSPEELPTQTLIFFFYDFDRFSKHEQIGCLMLDLGALDLSKLIEDWAEL 651
            +K +  LG L+ ++ Y P +  + V V   + L  ++  G+SDPYVK+++  K +   K +T IKRRTR+PV+NE F F V  +++   T +F   D+DR +++E IG ++  LG       +  W E+
Sbjct:  129 KKDRVPLGDLLVSLMYQPTNNRIIVVVMKANKLKAMDLTGSSDPYVKMYIMHKDRRLDKKKTTIKRRTRDPVWNESFIFDVPLDKIRDLTFVFNVMDYDRITQNELIGQVI--LGYRTTGSSLRHWTEM 255

[Close]

BLAST of Synaptotagmin 1 vs. Ensembl Nematostella
Match: EDO47762 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RKX9])

HSP 1 Score: 111.694 bits (278), Expect = 1.196e-27
Identity = 84/280 (30.00%), Postives = 150/280 (53.57%), Query Frame = 1

Query:  277 PKESLGKLVYAIKYFPESESLRVTVKSGHDL-IKLNTGGTSDPYVKVWLKEKPKLKFETKIKRRTRNPVFNEDFTFTVSPEELPTQTLIFFFYDFDRFSKHEQIGCLMLDLGALDLSKLIEDWAELDQP--SSDVNTEIPLGEICMSLKQDPDEEKLFVTILEAKGLRKHDEEDLYDPFLRLSLEEXXXXXXXXXXXXXXXXXPNPYYNEDFEFQLSAELSTKVQLVVTAFNCSNNNIKHSMPIGNIVLGPTITGSG--YKHWKEIISNSKRTIVRWHGL 1101
            P+  +G+L + I+Y    ++L VT+    +L  +  T  T DP+VK+ L  K K   +++ KR+T+ P FNE F   ++ +EL + TL F  +D  R S+   IG  M  L  ++ + + E W +L++P   S    ++ LG+I +SL   P  ++L + IL A  LR    +   DPF++++    G  V+K K T + + T NP +N+ F + ++ +      L+V+ ++ S   ++    IG ++LG  +   G   +HW E+++N ++ I  WH L
Sbjct:   26 PESHIGRLWFNIQYSTTGQNLVVTLVKARNLPSRSKTVRTCDPFVKIALLPKDKHVSQSRCKRKTKRPTFNETFYIPIAEDELDSSTLQFTVFDGYRMSQQAIIGEAMYPLIDMESTGIQELWRDLEKPIEVSQAKRKL-LGDIHISLSYYPTLDRLTIIILRAANLRTIGHKGT-DPFVKIAF-SIGNKVMKTKKTAVHQDTVNPMFNDAFNYTVTEDDLGTSSLLVSVWH-SGGGVREDKLIGRVLLGGMMYARGKECEHWTEMMTNPRKMIKYWHPL 301

[Close]

BLAST of Synaptotagmin 1 vs. Ensembl Nematostella
Match: EDO41933 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S352])

HSP 1 Score: 103.219 bits (256), Expect = 8.958e-25
Identity = 83/280 (29.64%), Postives = 135/280 (48.21%), Query Frame = 1

Query:  286 SLGKLVYAIKYFPESESLRVTVKSGHDLIKLNTGGTSDPYVKVWL----KEKPKLKFETKIKRRTRNPVFNEDFTF-TVSPEELPTQTLIFFFYDFDRFSKHEQIGCLMLDLGALDLSKLIEDWAELDQPSSDVNTEIPLGEICMSLKQDPDEEKLFVTILEAKGLRKHDEEDLYDPFLRLSLEEXXXXXXXXXXXXXXXXXPNPYYNEDFEFQLSAELSTKVQLVVTAFNCSNNNIKHSMPIGNIVLGPTITGSGYKHWKEIISNSKRTIVRWHGLVEV 1110
             LG L + ++Y      L V +     L  ++ GGTSDPYVK+ L     +  KL+  TK K  T NPVFNE  T+  ++ EE+ ++TL    +D D   +++ IG   ++L  L+ S   + +     P +  +   PLG I ++LK +     LFVT++   GL   D     DP+++  L+       K++    KK   NP +NE+F + ++     K  L VT ++      K +  IG ++L     GS  KHW +++    +   +WH L  V
Sbjct:   18 GLGLLEFTLRYQKLDSRLDVVLHDAKGLKPMDHGGTSDPYVKLHLLPGASKSNKLRSHTKYK--TLNPVFNETLTYYGITEEEISSKTLRLQVFDEDTIGRNDFIGETSINLKLLN-SNPTQTFKRSLIPKALDSPHSPLGRIQLALKYNTQRGMLFVTVMRCSGLASMDANGYSDPYVKCYLKPDPQKKSKRRTNIRKKTL-NPEFNEEFVYDIAHHELAKKSLEVTVWDYDVG--KSNDFIGGVILNINAEGSALKHWYDMLKGPNQLHTQWHTLENV 291

HSP 2 Score: 80.4925 bits (197), Expect = 8.146e-17
Identity = 44/119 (36.97%), Postives = 69/119 (57.98%), Query Frame = 1

Query:  262 KALEKPKESLGKLVYAIKYFPESESLRVTVKSGHDLIKLNTGGTSDPYVKVWLKEKP--KLKFETKIKRRTRNPVFNEDFTFTVSPEELPTQTLIFFFYDFDRFSKHEQIGCLMLDLGA 612
            KAL+ P   LG++  A+KY  +   L VTV     L  ++  G SDPYVK +LK  P  K K  T I+++T NP FNE+F + ++  EL  ++L    +D+D    ++ IG ++L++ A
Sbjct:  145 KALDSPHSPLGRIQLALKYNTQRGMLFVTVMRCSGLASMDANGYSDPYVKCYLKPDPQKKSKRRTNIRKKTLNPEFNEEFVYDIAHHELAKKSLEVTVWDYDVGKSNDFIGGVILNINA 263

[Close]

BLAST of Synaptotagmin 1 vs. Ensembl Nematostella
Match: EDO33081 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7ST78])

HSP 1 Score: 101.679 bits (252), Expect = 1.515e-24
Identity = 78/273 (28.57%), Postives = 126/273 (46.15%), Query Frame = 1

Query:  295 KLVYAIKYFPESESLRVTVKSGHDLIKLNTGGTSDPYVKVWLKEKPKLKFETKIKRRTRNPVFNEDFTFTVSPEELPTQTLIFFFYDFDRFSKHEQIGCLMLDLGALDLSKLIEDWAELDQPSSDVNTEIPLGEICMSLKQDPDEEKLFVTILEAKGLRKHDEEDL-YDPFLRLSLEEXXXXXXXXXXXXXXXXXPNPYYNEDFEFQLSAELSTKVQLVVTAFNCSNNNIKHSMPIGNIVLGPTI--TGSGYKHWKEIISNSKRTIVRWHGLV 1104
            +L +++ Y   +E L+V +     L        + PYVK+ L    K K ++  + R  NP FNEDF F+V  EEL  +TL F   DFDRFS+ + IG + L+ G                            ++  SL+  P   +L V IL+ K LR   EE    D ++++S+  GG  V K+K   +KK   NP +N+ F F +       V  V++          + + +G  V+GP +  T  G  HW +++ + +  + +WH L+
Sbjct:    5 RLCFSLNYSHYNEKLQVKLIRATRLTPKGNNVVATPYVKMCLLPDRKRKLQSTRRHRNSNPAFNEDFVFSVPAEELRMRTLKFTVCDFDRFSRQQVIGHVQLEKG----------------------------QLLFSLQYLPTACRLTVAILKGKDLRVEGEETTEIDTYVKVSMIMGGKAVKKRKTPVVKKTC-NPVFNQAFVFSMPPSYLENVSFVISVIATPKRG-GNKIHVGRAVVGPYMYSTSPGLSHWTDMLGSPRSAVAQWHSLI 247

[Close]

BLAST of Synaptotagmin 1 vs. Ensembl Medaka
Match: syt2a (synaptotagmin-2 [Source:NCBI gene;Acc:101161806])

HSP 1 Score: 207.608 bits (527), Expect = 1.368e-61
Identity = 118/271 (43.54%), Postives = 171/271 (63.10%), Query Frame = 1

Query:  289 LGKLVYAIKYFPESESLRVTVKSGHDLIKLNTGGTSDPYVKVWLKEKPKLKFETKIKRRTRNPVFNEDFTFTVSPEELPTQTLIFFFYDFDRFSKHEQIGCLMLDLGALDLSKLIEDWAELDQPSSDVNTEIPLGEICMSLKQDPDEEKLFVTILEAKGLRKHDEEDLYDPFLRLSLEEXXXXXXXXXXXXXXXXXPNPYYNEDFEFQLSAELSTKVQLVVTAFNCSNNNIKHSMPIGNIVLGPTITGSGYKHWKEIISNSKRTIVRWHGL 1101
            LGKL Y+I Y  +   L V +    DL+ +++GGTSDPYVKV++    K KF+TK+ ++T NPVFNE FTF +  +E+  +TL+   YDFDRFSKH+ IG + + +  LDL+K IE+W +LD  S+D      LG+IC+SL+  P   KL + ILEAK L+K D   L DP+++++L + G  + KKK T  K    NPYYNE F F++  E   K+Q V+T  +   + I  +  IG I +G   TG+G KHW ++++N +R I +WH L
Sbjct:  150 LGKLQYSIDYDFQENKLTVGILQAADLLSMDSGGTSDPYVKVFVLPDKKKKFDTKVHKKTLNPVFNETFTFKIPFQEMGGKTLVMSVYDFDRFSKHDVIGEIKIPMNTLDLAKPIEEWRDLD--SADQEEPEKLGDICISLRYVPTAGKLTICILEAKNLKKMDVGGLSDPYVKINLLQNGKRLKKKKTTVKKNTL-NPYYNESFSFEIPLEQMQKIQAVITVLDY--DKIGKNDAIGKIWVGSKSTGAGLKHWSDMLANPRRPIAQWHPL 415

HSP 2 Score: 58.9214 bits (141), Expect = 4.806e-9
Identity = 33/125 (26.40%), Postives = 65/125 (52.00%), Query Frame = 1

Query:  283 ESLGKLVYAIKYFPESESLRVTVKSGHDLIKLNTGGTSDPYVKVWLKEKPKLKFETKIKRRTR--NPVFNEDFTFTVSPEELPTQTLIFFFYDFDRFSKHEQIGCLMLDLGALDLSKLIEDWAEL 651
            E LG +  +++Y P +  L + +    +L K++ GG SDPYVK+ L +  K   + K   +    NP +NE F+F +  E++     +    D+D+  K++ IG +   +G+      ++ W+++
Sbjct:  279 EKLGDICISLRYVPTAGKLTICILEAKNLKKMDVGGLSDPYVKINLLQNGKRLKKKKTTVKKNTLNPYYNESFSFEIPLEQMQKIQAVITVLDYDKIGKNDAIGKIW--VGSKSTGAGLKHWSDM 401

[Close]

Query:  289 LGKLVYAIKYFPESESLRVTVKSGHDLIKLNTGGTSDPYVKVWLKEKPKLKFETKIKRRTRNPVFNEDFTFTVSPEELPTQTLIFFFYDFDRFSKHEQIGCLMLDLGALDLSKLIEDWAELDQPSSDVNTEIPLGEICMSLKQDPDEEKLFVTILEAKGLRKHDEEDLYDPFLRLSLEEXXXXXXXXXXXXXXXXXPNPYYNEDFEFQLSAELSTKVQLVVTAFNCSNNNIKHSMPIGNIVLGPTITGSGYKHWKEIISNSKRTIVRWHGL 1101
            LGKL Y+I Y  +   L V +    DL+ +++GGTSDPYVKV++    K KF+TK+ ++T NPVFNE FTF +  +E+  +TL+   YDFDRFSKH+ IG + + +  LDL+K IE+W +LD  S+D      LG+IC+SL+  P   KL + ILEAK L+K D   L DP+++++L + G  + KKK T  K    NPYYNE F F++  E   K+Q V+T  +   + I  +  IG I +G   TG+G KHW ++++N +R I +WH L
Sbjct:  150 LGKLQYSIDYDFQENKLTVGILQAADLLSMDSGGTSDPYVKVFVLPDKKKKFDTKVHKKTLNPVFNETFTFKIPFQEMGGKTLVMSVYDFDRFSKHDVIGEIKIPMNTLDLAKPIEEWRDLD--SADQEEPEKLGDICISLRYVPTAGKLTICILEAKNLKKMDVGGLSDPYVKINLLQNGKRLKKKKTTVKKNTL-NPYYNESFSFEIPLEQMQKIQAVITVLDY--DKIGKNDAIGKIWVGSKSTGAGLKHWSDMLANPRRPIAQWHPL 415

HSP 2 Score: 58.9214 bits (141), Expect = 4.806e-9
Identity = 33/125 (26.40%), Postives = 65/125 (52.00%), Query Frame = 1

Query:  283 ESLGKLVYAIKYFPESESLRVTVKSGHDLIKLNTGGTSDPYVKVWLKEKPKLKFETKIKRRTR--NPVFNEDFTFTVSPEELPTQTLIFFFYDFDRFSKHEQIGCLMLDLGALDLSKLIEDWAEL 651
            E LG +  +++Y P +  L + +    +L K++ GG SDPYVK+ L +  K   + K   +    NP +NE F+F +  E++     +    D+D+  K++ IG +   +G+      ++ W+++
Sbjct:  279 EKLGDICISLRYVPTAGKLTICILEAKNLKKMDVGGLSDPYVKINLLQNGKRLKKKKTTVKKNTLNPYYNESFSFEIPLEQMQKIQAVITVLDYDKIGKNDAIGKIW--VGSKSTGAGLKHWSDM 401

[Close]

BLAST of Synaptotagmin 1 vs. Ensembl Medaka
Match: ENSORLT00000042397.1 (synaptotagmin-2-like [Source:NCBI gene;Acc:101157206])

HSP 1 Score: 202.601 bits (514), Expect = 1.127e-59
Identity = 120/271 (44.28%), Postives = 168/271 (61.99%), Query Frame = 1

Query:  289 LGKLVYAIKYFPESESLRVTVKSGHDLIKLNTGGTSDPYVKVWLKEKPKLKFETKIKRRTRNPVFNEDFTFTVSPEELPTQTLIFFFYDFDRFSKHEQIGCLMLDLGALDLSKLIEDWAELDQPSSDVNTEIPLGEICMSLKQDPDEEKLFVTILEAKGLRKHDEEDLYDPFLRLSLEEXXXXXXXXXXXXXXXXXPNPYYNEDFEFQLSAELSTKVQLVVTAFNCSNNNIKHSMPIGNIVLGPTITGSGYKHWKEIISNSKRTIVRWHGL 1101
            LGKL Y+I+Y  E+  L V +    DL+ +++GGTSDPYV+V L    K KF+TK+ ++T NPVFNE F F V  EEL  +TL    YD+DRFSKH+ IG + L +  +DL + IE+W +L+  S+D      LG+IC+SL+  P   KL V ILEAK L+K D   L DP++++ L +GG  + KKK T  K    NPYYNE F F++  E   K+ + VT F+   + I  +  IG I +G   TG G KHW ++++N +R I +WH L
Sbjct:  148 LGKLQYSIEYDFENTKLTVGILQAADLMSMDSGGTSDPYVRVLLLPDKKKKFDTKVHKKTLNPVFNETFVFKVPYEELGGKTLCLSVYDYDRFSKHDVIGEVKLAMNTIDLGRPIEEWRDLE--SADQEEPEKLGDICISLRYVPTAGKLTVCILEAKNLKKMDACGLSDPYVKIQLLQGGKRLKKKKTTVKKNTL-NPYYNESFSFEIPLEQMQKILVAVTVFDY--DKIGKNDAIGKIFVGSKATGLGLKHWSDMLANPRRPIAQWHVL 413

[Close]

BLAST of Synaptotagmin 1 vs. Ensembl Medaka
Match: syt1a (synaptotagmin 1 [Source:NCBI gene;Acc:101166921])

HSP 1 Score: 196.823 bits (499), Expect = 1.677e-57
Identity = 117/278 (42.09%), Postives = 169/278 (60.79%), Query Frame = 1

Query:  274 KPKES--LGKLVYAIKYFPESESLRVTVKSGHDLIKLNTGGTSDPYVKVWLKEKPKLKFETKIKRRTRNPVFNEDFTFTVSPEELPTQTLIFFFYDFDRFSKHEQIGCLMLDLGALDLSKLIEDWAELDQPSSDVNTEIPLGEICMSLKQDPDEEKLFVTILEAKGLRKHDEEDLYDPFLRLSLEEXXXXXXXXXXXXXXXXXPNPYYNEDFEFQLSAELSTKVQLVVTAFNCSNNNIKHSMPIGNIVLGPTITGSGYKHWKEIISNSKRTIVRWHGL 1101
            +PKES  LGKL Y++ Y     +L V +    +L  ++ GGTSDPYVKV+L    K KFETK+ R+T NPVFNE FTF V   EL  +TL+   YDFDRFSKH+ IG + + +  +D S + E+W +L   S++   +  LG+IC SL+  P   KL V +LEAK L+K D   L DP++++ L + G  + KKK T  K    NPYYNE F F++  E   KVQ+V+T  +   + I  +  IG + +G   +G+  +HW ++++N +R I +WH L
Sbjct:  136 EPKESEKLGKLQYSLDYNFTENTLMVGIIQAAELPAMDMGGTSDPYVKVYLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYVELGGKTLVMTVYDFDRFSKHDAIGDIKVPMNKVDFSHVTEEWRDLQ--SAEKEEQEKLGDICFSLRYVPTAGKLTVVVLEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTL-NPYYNESFSFEVPFEQIQKVQIVITVLDY--DKIGKNDAIGKVFVGLNSSGTELRHWSDMLANPRRPIAQWHVL 408

[Close]

Query:  274 KPKES--LGKLVYAIKYFPESESLRVTVKSGHDLIKLNTGGTSDPYVKVWLKEKPKLKFETKIKRRTRNPVFNEDFTFTVSPEELPTQTLIFFFYDFDRFSKHEQIGCLMLDLGALDLSKLIEDWAELDQPSSDVNTEIPLGEICMSLKQDPDEEKLFVTILEAKGLRKHDEEDLYDPFLRLSLEEXXXXXXXXXXXXXXXXXPNPYYNEDFEFQLSAELSTKVQLVVTAFNCSNNNIKHSMPIGNIVLGPTITGSGYKHWKEIISNSKRTIVRWHGL 1101
            +PKES  LGKL Y++ Y     +L V +    +L  ++ GGTSDPYVKV+L    K KFETK+ R+T NPVFNE FTF V   EL  +TL+   YDFDRFSKH+ IG + + +  +D S + E+W +L   S++   +  LG+IC SL+  P   KL V +LEAK L+K D   L DP++++ L + G  + KKK T  K    NPYYNE F F++  E   KVQ+V+T  +   + I  +  IG + +G   +G+  +HW ++++N +R I +WH L
Sbjct:  136 EPKESEKLGKLQYSLDYNFTENTLMVGIIQAAELPAMDMGGTSDPYVKVYLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYVELGGKTLVMTVYDFDRFSKHDAIGDIKVPMNKVDFSHVTEEWRDLQ--SAEKEEQEKLGDICFSLRYVPTAGKLTVVVLEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTL-NPYYNESFSFEVPFEQIQKVQIVITVLDY--DKIGKNDAIGKVFVGLNSSGTELRHWSDMLANPRRPIAQWHVL 408

[Close]

BLAST of Synaptotagmin 1 vs. Planmine SMEST
Match: SMESG000059797.1 (SMESG000059797.1)

HSP 1 Score: 597.045 bits (1538), Expect = 0.000e+0
Identity = 340/342 (99.42%), Postives = 341/342 (99.71%), Query Frame = 1

Query:  100 MNTMXXXXXXXXXXXXXXXCWIMYRHFYRKKNDKIVFDXXXXXXXXXXXXXVSLKALEKPKESLGKLVYAIKYFPESESLRVTVKSGHDLIKLNTGGTSDPYVKVWLKEKPKLKFETKIKRRTRNPVFNEDFTFTVSPEELPTQTLIFFFYDFDRFSKHEQIGCLMLDLGALDLSKLIEDWAELDQPSSDVNTEIPLGEICMSLKQDPDEEKLFVTILEAKGLRKHDEEDLYDPFLRLSLEEXXXXXXXXXXXXXXXXXPNPYYNEDFEFQLSAELSTKVQLVVTAFNCSNNNIKHSMPIGNIVLGPTITGSGYKHWKEIISNSKRTIVRWHGLVEVVDNKK 1125
            MNTMILIISSILAVSIAAICWIMYRHFYRKKNDKIVFDKLEKKAAELNLEEVSLKALEKPKESLGKLVYAIKYFPESESLRVTVKSGHDLIKLNTGGTSDPYVKVWLKEKPKLKFETK+KRRTRNPVFNEDFTFTVSPEELPTQTLIFFFYDFDRFSKHEQIGCLMLDLGALDLSKLIEDWAELDQPSSDVNTEIPLGEICMSLKQDPDEEKLFVTILEAKGLRKHDEEDLYDPFLRLSLEEGGGIVIKKKFTTIKKATPNPYYNEDFEFQLSAELSTKVQLVVTAFNCSNNNIKHSMPIGNIVLGPTITGSGYKHWKEIISN KRTIVRWHGLVEVVDNKK
Sbjct:    1 MNTMILIISSILAVSIAAICWIMYRHFYRKKNDKIVFDKLEKKAAELNLEEVSLKALEKPKESLGKLVYAIKYFPESESLRVTVKSGHDLIKLNTGGTSDPYVKVWLKEKPKLKFETKVKRRTRNPVFNEDFTFTVSPEELPTQTLIFFFYDFDRFSKHEQIGCLMLDLGALDLSKLIEDWAELDQPSSDVNTEIPLGEICMSLKQDPDEEKLFVTILEAKGLRKHDEEDLYDPFLRLSLEEGGGIVIKKKFTTIKKATPNPYYNEDFEFQLSAELSTKVQLVVTAFNCSNNNIKHSMPIGNIVLGPTITGSGYKHWKEIISNPKRTIVRWHGLVEVVDNKK 342

[Close]

BLAST of Synaptotagmin 1 vs. Planmine SMEST
Match: SMESG000059797.1 (SMESG000059797.1)

HSP 1 Score: 592.038 bits (1525), Expect = 0.000e+0
Identity = 321/323 (99.38%), Postives = 322/323 (99.69%), Query Frame = 1

Query:  157 CWIMYRHFYRKKNDKIVFDXXXXXXXXXXXXXVSLKALEKPKESLGKLVYAIKYFPESESLRVTVKSGHDLIKLNTGGTSDPYVKVWLKEKPKLKFETKIKRRTRNPVFNEDFTFTVSPEELPTQTLIFFFYDFDRFSKHEQIGCLMLDLGALDLSKLIEDWAELDQPSSDVNTEIPLGEICMSLKQDPDEEKLFVTILEAKGLRKHDEEDLYDPFLRLSLEEXXXXXXXXXXXXXXXXXPNPYYNEDFEFQLSAELSTKVQLVVTAFNCSNNNIKHSMPIGNIVLGPTITGSGYKHWKEIISNSKRTIVRWHGLVEVVDNKK 1125
            CWIMYRHFYRKKNDKIVFDKLEKKAAELNLEEVSLKALEKPKESLGKLVYAIKYFPESESLRVTVKSGHDLIKLNTGGTSDPYVKVWLKEKPKLKFETK+KRRTRNPVFNEDFTFTVSPEELPTQTLIFFFYDFDRFSKHEQIGCLMLDLGALDLSKLIEDWAELDQPSSDVNTEIPLGEICMSLKQDPDEEKLFVTILEAKGLRKHDEEDLYDPFLRLSLEEGGGIVIKKKFTTIKKATPNPYYNEDFEFQLSAELSTKVQLVVTAFNCSNNNIKHSMPIGNIVLGPTITGSGYKHWKEIISN KRTIVRWHGLVEVVDNKK
Sbjct:   17 CWIMYRHFYRKKNDKIVFDKLEKKAAELNLEEVSLKALEKPKESLGKLVYAIKYFPESESLRVTVKSGHDLIKLNTGGTSDPYVKVWLKEKPKLKFETKVKRRTRNPVFNEDFTFTVSPEELPTQTLIFFFYDFDRFSKHEQIGCLMLDLGALDLSKLIEDWAELDQPSSDVNTEIPLGEICMSLKQDPDEEKLFVTILEAKGLRKHDEEDLYDPFLRLSLEEGGGIVIKKKFTTIKKATPNPYYNEDFEFQLSAELSTKVQLVVTAFNCSNNNIKHSMPIGNIVLGPTITGSGYKHWKEIISNPKRTIVRWHGLVEVVDNKK 339

[Close]

BLAST of Synaptotagmin 1 vs. Planmine SMEST
Match: SMESG000025329.1 (SMESG000025329.1)

HSP 1 Score: 226.483 bits (576), Expect = 2.578e-69
Identity = 136/283 (48.06%), Postives = 180/283 (63.60%), Query Frame = 1

Query:  271 EKPKESLGKLVYAIKYFPESESLRVTVKSGHDLIKLNTGGTSDPYVKVWLKEKPKLKFETKIKRRTRNPVFNEDFTFTVSPEELPTQTLIFFFYDFDRFSKHEQIGCLMLDLGALDLSKLIEDWAELDQPSSDVNTEIPLGEICMSLKQDPDEEKLFVTILEAKGLRKHDEEDLYDPFLRLSLEEXXXXXXXXXXXXXXXXXPNPYYNEDFEFQLSAELSTKVQLVVTAFNCSNNNIKHSMPIGNIVLGPTITGSGYKHWKEIISNSKRTIVRWHGLVEVVDN 1119
            EK    LGKL Y++ Y  +   L V V    DL  ++  GTSDPYVK++L    K KFETK+ R+  NPVFNE F F V   E+ ++TLIF  YDFDRFSKH+QIG + + LGA+DL ++IE+W EL+ P +D   E  LG+IC SL+  P   KL + ILEAK L+K D   L DP+++LSL    G  +KKK TTIKK T NPYYNE F F++  E   KV L+VT  +   + I  S PIG IVLG   TG+  +HW ++++N +R I +WH L E+ +N
Sbjct:  115 EKEDVHLGKLQYSLDYDFQKGELTVGVIQATDLPAMDMSGTSDPYVKLYLLPDKKKKFETKVHRKILNPVFNETFVFKVPFNEVASKTLIFNVYDFDRFSKHDQIGQIKVPLGAIDLGRVIEEWKELESPENDGEKENRLGDICFSLRYVPTSGKLTIVILEAKNLKKMDVGGLSDPYVKLSL-MLNGKRVKKKKTTIKKYTLNPYYNESFSFEVPFEQIQKVNLIVTVVDY--DRIGTSEPIGRIVLGCNATGAELRHWSDMLANPRRPIAQWHTLQEMPEN 394

[Close]

BLAST of Synaptotagmin 1 vs. Planmine SMEST
Match: SMESG000055143.1 (SMESG000055143.1)

HSP 1 Score: 220.705 bits (561), Expect = 6.512e-67
Identity = 132/279 (47.31%), Postives = 176/279 (63.08%), Query Frame = 1

Query:  265 ALEKPKESLGKLVYAIKYFPESESLRVTVKSGHDLIKLNTGGTSDPYVKVWLKEKPKLKFETKIKRRTRNPVFNEDFTFTVSPEELPTQTLIFFFYDFDRFSKHEQIGCLMLDLGALDLSKLIEDWAELDQPSSDVNTEIPLGEICMSLKQDPDEEKLFVTILEAKGLRKHDEEDLYDPFLRLSLEEXXXXXXXXXXXXXXXXXPNPYYNEDFEFQLSAELSTKVQLVVTAFNCSNNNIKHSMPIGNIVLGPTITGSGYKHWKEIISNSKRTIVRWHGL 1101
            A +K   +LGKL Y++ Y      L V V    DL  ++  GTSDPYVKV+L    K KFETK+ R+  NPVFNE F F +   E+ ++TL+F  +DFDRFSKH+QIG + + LG++DL K+IE+W EL  P SD   E  LG+IC SL+  P   KL + ILEAK L+K D   L DP+++LSL    G  +KKK TTIKK T NPYYNE F F++  E   KV L+VT  +   + I  S PIG +VLG   TG+  +HW ++++N +R I +WH L
Sbjct:  126 AQDKEAVNLGKLQYSLDYDFTKGELTVGVVQATDLPAMDMSGTSDPYVKVFLLPDKKKKFETKVHRKILNPVFNETFVFKIPYSEVGSKTLVFNVFDFDRFSKHDQIGQIQIPLGSVDLCKVIEEWKELGPPDSDNEKENRLGDICFSLRYVPTSGKLNIVILEAKNLKKMDVGGLSDPYVKLSL-MLNGKRVKKKKTTIKKYTLNPYYNESFSFEVPFEQIQKVNLIVTVVDY--DRIGTSEPIGRVVLGCNATGAELRHWSDMLANPRRPIAQWHTL 401

[Close]

BLAST of Synaptotagmin 1 vs. Planmine SMEST
Match: SMESG000055143.1 (SMESG000055143.1)

HSP 1 Score: 220.32 bits (560), Expect = 7.239e-67
Identity = 132/279 (47.31%), Postives = 176/279 (63.08%), Query Frame = 1

Query:  265 ALEKPKESLGKLVYAIKYFPESESLRVTVKSGHDLIKLNTGGTSDPYVKVWLKEKPKLKFETKIKRRTRNPVFNEDFTFTVSPEELPTQTLIFFFYDFDRFSKHEQIGCLMLDLGALDLSKLIEDWAELDQPSSDVNTEIPLGEICMSLKQDPDEEKLFVTILEAKGLRKHDEEDLYDPFLRLSLEEXXXXXXXXXXXXXXXXXPNPYYNEDFEFQLSAELSTKVQLVVTAFNCSNNNIKHSMPIGNIVLGPTITGSGYKHWKEIISNSKRTIVRWHGL 1101
            A +K   +LGKL Y++ Y      L V V    DL  ++  GTSDPYVKV+L    K KFETK+ R+  NPVFNE F F +   E+ ++TL+F  +DFDRFSKH+QIG + + LG++DL K+IE+W EL  P SD   E  LG+IC SL+  P   KL + ILEAK L+K D   L DP+++LSL    G  +KKK TTIKK T NPYYNE F F++  E   KV L+VT  +   + I  S PIG +VLG   TG+  +HW ++++N +R I +WH L
Sbjct:  122 AQDKEAVNLGKLQYSLDYDFTKGELTVGVVQATDLPAMDMSGTSDPYVKVFLLPDKKKKFETKVHRKILNPVFNETFVFKIPYSEVGSKTLVFNVFDFDRFSKHDQIGQIQIPLGSVDLCKVIEEWKELGPPDSDNEKENRLGDICFSLRYVPTSGKLNIVILEAKNLKKMDVGGLSDPYVKLSL-MLNGKRVKKKKTTIKKYTLNPYYNESFSFEVPFEQIQKVNLIVTVVDY--DRIGTSEPIGRVVLGCNATGAELRHWSDMLANPRRPIAQWHTL 397

The following BLAST results are available for this feature:

BLAST of Synaptotagmin 1 vs. Ensembl Human
BLAST of Synaptotagmin 1 vs. Ensembl Celegans
BLAST of Synaptotagmin 1 vs. Ensembl Fly
BLAST of Synaptotagmin 1 vs. Ensembl Zebrafish
BLAST of Synaptotagmin 1 vs. Ensembl Xenopus
BLAST of Synaptotagmin 1 vs. Ensembl Mouse
BLAST of Synaptotagmin 1 vs. UniProt/SwissProt
BLAST of Synaptotagmin 1 vs. TrEMBL
BLAST of Synaptotagmin 1 vs. Ensembl Cavefish
BLAST of Synaptotagmin 1 vs. Ensembl Sea Lamprey
BLAST of Synaptotagmin 1 vs. Ensembl Yeast
BLAST of Synaptotagmin 1 vs. Ensembl Nematostella
BLAST of Synaptotagmin 1 vs. Ensembl Medaka
BLAST of Synaptotagmin 1 vs. Planmine SMEST

BLAST of Synaptotagmin 1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
SYT1	1.013e-56	42.80	synaptotagmin 1 [Source:HGNC Symbol;Acc:HGNC:11509...	[more]
SYT1	1.013e-56	42.80	synaptotagmin 1 [Source:HGNC Symbol;Acc:HGNC:11509...	[more]
SYT1	1.013e-56	42.80	synaptotagmin 1 [Source:HGNC Symbol;Acc:HGNC:11509...	[more]
SYT1	1.404e-56	42.80	synaptotagmin 1 [Source:HGNC Symbol;Acc:HGNC:11509...	[more]
SYT2	4.445e-56	42.28	synaptotagmin 2 [Source:HGNC Symbol;Acc:HGNC:11510...	[more]

BLAST of Synaptotagmin 1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
snt-1	2.665e-56	42.44	Synaptotagmin-1 [Source:UniProtKB/Swiss-Prot;Acc:...	[more]
snt-1	3.313e-54	42.28	Synaptotagmin-1 [Source:UniProtKB/Swiss-Prot;Acc:...	[more]
snt-3	4.355e-54	37.55	SyNapTotagmin [Source:UniProtKB/TrEMBL;Acc:Q965S5...	[more]
snt-3	4.355e-54	37.55	SyNapTotagmin [Source:UniProtKB/TrEMBL;Acc:Q965S5...	[more]
snt-2	6.181e-45	35.19	Synaptotagmin 2 [Source:UniProtKB/Swiss-Prot;Acc:...	[more]

BLAST of Synaptotagmin 1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Syt1	8.580e-58	42.60	gene:FBgn0004242 transcript:FBtr0077726	[more]
Syt1	1.088e-57	42.60	gene:FBgn0004242 transcript:FBtr0077728	[more]
Syt1	1.088e-57	42.60	gene:FBgn0004242 transcript:FBtr0345331	[more]
Syt1	1.088e-57	42.60	gene:FBgn0004242 transcript:FBtr0077727	[more]
Syt1	3.029e-57	42.24	gene:FBgn0004242 transcript:FBtr0343993	[more]

BLAST of Synaptotagmin 1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
syt1a	1.372e-56	42.07	synaptotagmin Ia [Source:ZFIN;Acc:ZDB-GENE-040718-...	[more]
syt1a	1.372e-56	42.07	synaptotagmin Ia [Source:ZFIN;Acc:ZDB-GENE-040718-...	[more]
syt2a	1.645e-54	39.85	synaptotagmin IIa [Source:ZFIN;Acc:ZDB-GENE-060503...	[more]
syt2a	1.645e-54	39.85	synaptotagmin IIa [Source:ZFIN;Acc:ZDB-GENE-060503...	[more]
syt5b	5.966e-51	38.24	synaptotagmin Vb [Source:ZFIN;Acc:ZDB-GENE-050522-...	[more]

BLAST of Synaptotagmin 1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
SYT5	3.390e-61	42.96	synaptotagmin 5 [Source:NCBI gene;Acc:100493612]	[more]
SYT5	4.645e-61	42.96	synaptotagmin 5 [Source:NCBI gene;Acc:100493612]	[more]
e2f4	1.559e-57	42.65	E2F transcription factor 4 [Source:Xenbase;Acc:XB-...	[more]
syt8	4.041e-53	36.23	synaptotagmin 8 [Source:NCBI gene;Acc:100037878]	[more]
luzp2	3.232e-51	39.85	leucine zipper protein 2 [Source:Xenbase;Acc:XB-GE...	[more]

BLAST of Synaptotagmin 1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Syt1	6.511e-57	42.80	synaptotagmin I [Source:MGI Symbol;Acc:MGI:99667]	[more]
Syt1	6.511e-57	42.80	synaptotagmin I [Source:MGI Symbol;Acc:MGI:99667]	[more]
Syt2	3.418e-56	42.28	synaptotagmin II [Source:MGI Symbol;Acc:MGI:99666]	[more]
Syt2	3.418e-56	42.28	synaptotagmin II [Source:MGI Symbol;Acc:MGI:99666]	[more]
Syt5	7.157e-44	36.86	synaptotagmin V [Source:MGI Symbol;Acc:MGI:1926368...	[more]

BLAST of Synaptotagmin 1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|P41823\|SY65_APLCA	1.257e-62	43.37	Synaptotagmin-1 OS=Aplysia californica OX=6500 GN=...	[more]
sp\|P21521\|SY65_DROME	8.600e-57	42.60	Synaptotagmin 1 OS=Drosophila melanogaster OX=7227...	[more]
sp\|Q5R4J5\|SYT1_PONAB	2.413e-56	42.44	Synaptotagmin-1 OS=Pongo abelii OX=9601 GN=SYT1 PE...	[more]
sp\|P46096\|SYT1_MOUSE	4.554e-56	42.80	Synaptotagmin-1 OS=Mus musculus OX=10090 GN=Syt1 P...	[more]
sp\|P21579\|SYT1_HUMAN	4.864e-56	42.80	Synaptotagmin-1 OS=Homo sapiens OX=9606 GN=SYT1 PE...	[more]

BLAST of Synaptotagmin 1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A267E333	1.529e-70	47.87	Uncharacterized protein OS=Macrostomum lignano OX=...	[more]
A0A267GS86	1.737e-70	47.87	Uncharacterized protein OS=Macrostomum lignano OX=...	[more]
A0A267E6V1	6.572e-70	47.86	Uncharacterized protein OS=Macrostomum lignano OX=...	[more]
A0A1D2ML67	1.375e-65	45.23	Synaptotagmin 1 (Fragment) OS=Orchesella cincta OX...	[more]
A0A267EMR3	1.669e-65	45.99	Uncharacterized protein OS=Macrostomum lignano OX=...	[more]

BLAST of Synaptotagmin 1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ENSAMXT00000017640.2	2.539e-59	42.12	synaptotagmin-1-like [Source:NCBI gene;Acc:1030358...	[more]
syt1b	4.481e-57	41.22	synaptotagmin Ib [Source:ZFIN;Acc:ZDB-GENE-060503-...	[more]
syt1b	4.778e-57	41.22	synaptotagmin Ib [Source:ZFIN;Acc:ZDB-GENE-060503-...	[more]
syt1a	1.090e-56	41.43	synaptotagmin 1 [Source:NCBI gene;Acc:103044539]	[more]
syt1a	1.415e-56	41.43	synaptotagmin 1 [Source:NCBI gene;Acc:103044539]	[more]

BLAST of Synaptotagmin 1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5


Match Name	E-value	Identity	Description
syt2a	8.604e-30	47.93	synaptotagmin IIa [Source:ZFIN;Acc:ZDB-GENE-060503...	[more]
SYT5	8.966e-30	42.97	synaptotagmin 5 [Source:HGNC Symbol;Acc:HGNC:11513...	[more]
syt2a	1.192e-29	47.93	synaptotagmin IIa [Source:ZFIN;Acc:ZDB-GENE-060503...	[more]
SYT6	6.930e-23	43.90	synaptotagmin 6 [Source:HGNC Symbol;Acc:HGNC:18638...	[more]
SYT6	7.505e-23	41.46	synaptotagmin 6 [Source:HGNC Symbol;Acc:HGNC:18638...	[more]

BLAST of Synaptotagmin 1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 3


Match Name	E-value	Identity	Description
TCB2	9.213e-9	29.25	ER protein involved in ER-plasma membrane tetherin...	[more]
TCB3	1.739e-8	31.19	Cortical ER protein involved in ER-plasma membrane...	[more]
TCB1	3.974e-6	25.90	Lipid-binding ER protein involved in ER-plasma mem...	[more]

BLAST of Synaptotagmin 1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO31746	1.266e-44	34.91	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO43704	5.816e-35	30.11	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO47762	1.196e-27	30.00	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO41933	8.958e-25	29.64	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO33081	1.515e-24	28.57	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of Synaptotagmin 1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
syt2a	1.368e-61	43.54	synaptotagmin-2 [Source:NCBI gene;Acc:101161806]	[more]
syt2a	1.368e-61	43.54	synaptotagmin-2 [Source:NCBI gene;Acc:101161806]	[more]
ENSORLT00000042397.1	1.127e-59	44.28	synaptotagmin-2-like [Source:NCBI gene;Acc:1011572...	[more]
syt1a	1.677e-57	42.09	synaptotagmin 1 [Source:NCBI gene;Acc:101166921]	[more]
syt1a	1.677e-57	42.09	synaptotagmin 1 [Source:NCBI gene;Acc:101166921]	[more]

BLAST of Synaptotagmin 1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000059797.1	0.000e+0	99.42	SMESG000059797.1	[more]
SMESG000059797.1	0.000e+0	99.38	SMESG000059797.1	[more]
SMESG000025329.1	2.578e-69	48.06	SMESG000025329.1	[more]
SMESG000055143.1	6.512e-67	47.31	SMESG000055143.1	[more]
SMESG000055143.1	7.239e-67	47.31	SMESG000055143.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30018598 ID=SMED30018598|Name=Synaptotagmin 1|organism=Schmidtea mediterranea sexual|type=transcript|length=1426bp
GCCATATGCCACCTCCATGTTGCCCATAGCATAACAGTCATAATTTTTTT
TTCAAGTGTAAATCGATATATTTATAGAGGAGCACTGACACCATAAAAAA
TGAACACGATGATTCTTATTATTTCTAGTATTCTTGCTGTCAGCATTGCC
GCCATATGCTGGATCATGTACCGACACTTCTATAGAAAGAAAAACGACAA
AATAGTTTTCGATAAACTGGAGAAGAAAGCAGCAGAACTCAATTTAGAAG
AGGTCAGTTTGAAAGCGCTAGAAAAACCTAAAGAAAGTCTTGGGAAATTG
GTTTATGCAATAAAATACTTTCCTGAATCGGAATCTCTCCGAGTGACGGT
GAAATCAGGACACGATCTTATCAAGTTAAACACCGGTGGAACGTCAGATC
CATACGTGAAAGTCTGGCTTAAAGAGAAACCAAAATTAAAATTCGAAACC
AAAATCAAAAGACGGACGAGAAATCCAGTTTTCAATGAAGATTTTACATT
TACGGTATCACCCGAAGAACTTCCAACTCAAACTTTGATATTTTTTTTCT
ATGATTTTGACAGATTTTCCAAACACGAGCAAATCGGCTGTCTGATGCTA
GATTTGGGTGCATTAGATCTTAGCAAACTGATTGAAGATTGGGCTGAACT
CGATCAACCTAGCAGTGATGTCAACACGGAAATACCTTTAGGAGAAATTT
GTATGTCATTAAAACAGGATCCAGACGAAGAGAAATTATTTGTTACAATA
TTAGAAGCAAAAGGTTTAAGGAAACACGACGAAGAGGATTTATACGATCC
TTTTCTGCGTTTATCCTTAGAAGAAGGAGGAGGGATAGTCATCAAAAAGA
AGTTCACAACAATAAAAAAGGCAACTCCCAACCCATATTATAATGAGGAT
TTTGAGTTTCAACTATCCGCCGAGTTATCTACGAAAGTGCAATTGGTAGT
CACTGCATTCAATTGCAGCAATAACAACATCAAGCATAGCATGCCAATCG
GAAATATCGTTTTGGGCCCAACCATTACTGGATCTGGATATAAACATTGG
AAAGAAATTATCAGCAATTCCAAAAGAACAATTGTTCGTTGGCACGGATT
AGTCGAGGTGGTCGACAATAAAAAATGAATGATGTTATCAAAGACTGTAT
GAAACATTTATTTATCCTATGATACCTGTTTGCTGTTATTTATCAAAATA
ACCCAGTCTAGGGCCTATTAAATTATAATTTATTGACAAGTCAAATGGGG
CAGAAATTCCAACCTTTCTTTCGATTGTAGTAAGACGTTTTGAGATATGG
GATTAAAAAGGTGCTAGACCTCTTTGTGGATATCTTTGAAAAAGAACGTT
ATATCAACAGTAAGTCTTTACAGTTTTAGAAACTAAAAATTAAAAGCTTT
TAAGAGTTACTAAATGTTTCGTTCAT

protein sequence of SMED30018598-orf-1

>SMED30018598-orf-1 ID=SMED30018598-orf-1|Name=SMED30018598-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=343bp
MNTMILIISSILAVSIAAICWIMYRHFYRKKNDKIVFDKLEKKAAELNLE
EVSLKALEKPKESLGKLVYAIKYFPESESLRVTVKSGHDLIKLNTGGTSD
PYVKVWLKEKPKLKFETKIKRRTRNPVFNEDFTFTVSPEELPTQTLIFFF
YDFDRFSKHEQIGCLMLDLGALDLSKLIEDWAELDQPSSDVNTEIPLGEI
CMSLKQDPDEEKLFVTILEAKGLRKHDEEDLYDPFLRLSLEEGGGIVIKK
KFTTIKKATPNPYYNEDFEFQLSAELSTKVQLVVTAFNCSNNNIKHSMPI
GNIVLGPTITGSGYKHWKEIISNSKRTIVRWHGLVEVVDNKK*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000421	tail

Vocabulary: **INTERPRO**
Term	Definition
IPR035892	C2_domain_sf
IPR000008	C2_dom

Vocabulary: **molecular function**
Term	Definition
GO:0005515	protein binding
GO:0005544	calcium-dependent phospholipid binding

Vocabulary: **biological process**
Term	Definition
GO:0007269	neurotransmitter secretion

Vocabulary: **cellular component**
Term	Definition
GO:0008021	synaptic vesicle
GO:0016020	membrane

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
None	No IPR available	COILS	Coil	Coil	coord: 30..57
None	No IPR available	PANTHER	PTHR10024:SF227	SYNAPTOTAGMIN 1	coord: 5..336
None	No IPR available	PANTHER	PTHR10024	SYNAPTOTAGMIN	coord: 5..336
None	No IPR available	SUPERFAMILY	SSF49562	C2 domain (Calcium/lipid-binding domain, CaLB)	coord: 197..334
None	No IPR available	SUPERFAMILY	SSF49562	C2 domain (Calcium/lipid-binding domain, CaLB)	coord: 59..189
None	No IPR available	TMHMM	TMhelix		coord: 5..27
IPR000008	C2 domain	PRINTS	PR00360	C2DOMAIN	coord: 95..107 score: 58.86 coord: 146..154 score: 40.05 coord: 122..135 score: 48.17
IPR000008	C2 domain	SMART	SM00239	C2_3c	coord: 212..329 e-value: 2.1E-9 score: 47.3 coord: 79..181 e-value: 1.6E-18 score: 77.5
IPR000008	C2 domain	PFAM	PF00168	C2	coord: 212..317 e-value: 2.7E-10 score: 40.5 coord: 79..184 e-value: 6.8E-22 score: 77.7
IPR000008	C2 domain	PROSITE	PS50004	C2	coord: 212..304 score: 13.239
IPR000008	C2 domain	PROSITE	PS50004	C2	coord: 79..166 score: 16.613
IPR035892	C2 domain superfamily	GENE3D	G3DSA:2.60.40.150		coord: 52..189 e-value: 5.3E-36 score: 125.6
IPR035892	C2 domain superfamily	GENE3D	G3DSA:2.60.40.150		coord: 190..336 e-value: 1.2E-29 score: 104.8

Main menu

Synaptotagmin 1

Zeng et. al., 2018

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 2

Owlery

blazegraph-runner