slc4a-1

Overview
Nameslc4a-1 (AKN21407.1)
Smed IDSMED30018542
Length (bp)3938
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of slc4a-1 (SMED30018542) t-SNE clustered cells

Violin plots show distribution of expression levels for slc4a-1 (SMED30018542) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of slc4a-1 (SMED30018542) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for slc4a-1 (SMED30018542) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30018542

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 52

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
X1 cellSMED30018542h1SMcG0021166 SmedASXL_011532SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015
FACS sorted cell population asexual adult RNA-sequencing evidence
X1 cellSMED30018542h1SMcG0021165 SmedASXL_011532SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015
FACS sorted cell population asexual adult RNA-sequencing evidence
X1 cellSMED30018542h1SMcG0021166 SmedASXL_011532SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015
FACS sorted cell population asexual adult RNA-sequencing evidence
X1 cellSMED30018542h1SMcG0021165 SmedASXL_011532SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015
FACS sorted cell population asexual adult RNA-sequencing evidence
Smed sexual biotypeSMED30018542h1SMcG0021165 Contig49492uc_Smed_v2PMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30018542h1SMcG0021165 Contig49492newmark_estsPMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
muscle cellSMED30018542h1SMcG0021165 dd_Smed_v4_3003_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30018542h1SMcG0021165 dd_Smed_v4_3003_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
pharynxSMED30018542h1SMcG0021165 dd_Smed_v4_3003_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
nervous systemSMED30018542h1SMcG0021165 dd_Smed_v4_3003_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
gutSMED30018542h1SMcG0021165 dd_Smed_v4_3003_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30018542h1SMcG0021165 dd_Smed_v4_3003_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30018542h1SMcG0021165 dd_Smed_v4_3003_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30018542h1SMcG0021165 dd_Smed_v4_3003_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
non-ciliated neuronSMED30018542h1SMcG0021165 dd_Smed_v4_3003_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
muscle cellSMED30018542h1SMcG0021166 dd_Smed_v4_3003_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30018542h1SMcG0021166 dd_Smed_v4_3003_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
pharynxSMED30018542h1SMcG0021166 dd_Smed_v4_3003_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
nervous systemSMED30018542h1SMcG0021166 dd_Smed_v4_3003_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
gutSMED30018542h1SMcG0021166 dd_Smed_v4_3003_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30018542h1SMcG0021166 dd_Smed_v4_3003_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30018542h1SMcG0021166 dd_Smed_v4_3003_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30018542h1SMcG0021166 dd_Smed_v4_3003_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
non-ciliated neuronSMED30018542h1SMcG0021166 dd_Smed_v4_3003_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30018542h1SMcG0021166 Contig49492uc_Smed_v2PMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30018542h1SMcG0021166 Contig49492newmark_estsPMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30018542h1SMcG0021165 Contig49492uc_Smed_v2PMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30018542h1SMcG0021165 Contig49492newmark_estsPMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
muscle cellSMED30018542h1SMcG0021165 dd_Smed_v4_3003_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30018542h1SMcG0021165 dd_Smed_v4_3003_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
pharynxSMED30018542h1SMcG0021165 dd_Smed_v4_3003_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
nervous systemSMED30018542h1SMcG0021165 dd_Smed_v4_3003_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
gutSMED30018542h1SMcG0021165 dd_Smed_v4_3003_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30018542h1SMcG0021165 dd_Smed_v4_3003_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30018542h1SMcG0021165 dd_Smed_v4_3003_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30018542h1SMcG0021165 dd_Smed_v4_3003_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
non-ciliated neuronSMED30018542h1SMcG0021165 dd_Smed_v4_3003_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
muscle cellSMED30018542h1SMcG0021166 dd_Smed_v4_3003_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30018542h1SMcG0021166 dd_Smed_v4_3003_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
pharynxSMED30018542h1SMcG0021166 dd_Smed_v4_3003_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
nervous systemSMED30018542h1SMcG0021166 dd_Smed_v4_3003_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
gutSMED30018542h1SMcG0021166 dd_Smed_v4_3003_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30018542h1SMcG0021166 dd_Smed_v4_3003_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30018542h1SMcG0021166 dd_Smed_v4_3003_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30018542h1SMcG0021166 dd_Smed_v4_3003_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
non-ciliated neuronSMED30018542h1SMcG0021166 dd_Smed_v4_3003_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30018542h1SMcG0021166 Contig49492uc_Smed_v2PMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30018542h1SMcG0021166 Contig49492newmark_estsPMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
head regionSMED30018542h1SMcG0021166 OX_Smed_1.0.11823ox_Smed_v2PMID:24238224
Kao et al., 2013
whole organism asexual adult RNA-sequencing evidence
head regionSMED30018542h1SMcG0021165 OX_Smed_1.0.11823ox_Smed_v2PMID:24238224
Kao et al., 2013
whole organism asexual adult RNA-sequencing evidence
head regionSMED30018542h1SMcG0021166 OX_Smed_1.0.11823ox_Smed_v2PMID:24238224
Kao et al., 2013
whole organism asexual adult RNA-sequencing evidence
head regionSMED30018542h1SMcG0021165 OX_Smed_1.0.11823ox_Smed_v2PMID:24238224
Kao et al., 2013
whole organism asexual adult RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of slc4a-1 vs. Ensembl Human
Match: SLC4A10 (solute carrier family 4 member 10 [Source:HGNC Symbol;Acc:HGNC:13811])

HSP 1 Score: 944.11 bits (2439), Expect = 0.000e+0
Identity = 545/1152 (47.31%), Postives = 739/1152 (64.15%), Query Frame = 2
Query:  125 DEPILDRG----FQFTHYHPSEDEIEDHRSQRALYIGVHMPPDXXXXXXXXXXXXXXXXXXXXXDKKDYLTEIAEDDTEKATDPSQHVMFLLG-EDEDEE--THNLFCEMDELRLDDEGEPEWKETARWIKFEEDVEEGGERWSKPHVASLSLYSLFEVRNCITSAVNMFNVEANNFETIIEIILNKIVSEKKISPDQREKVKEMLQRKHVHLHERRHKSNAKGSQLPLIRSLADIGKKYSSKEVDKVQLQRRNSDYPTKFTRFDANXXXXXXXXXXXXXYVDKNRIDVDQCGSDNLASQKFDLHFFKKIPLGAETSNIMVGETDFLNQMVVVFIRLKEAVILGELTEVPVPTRFVFVMLGPQGSAVKNHEIGRSMATLMSDDVFHDVAYKARNLDDLLAGIDEFLSNCTVLPPAEWDPSIRIEPPKSGPIA--RKVPSMPNGAQALLTASGDGRXXXXXXXXXXXXXXASVVNKLQPVEEESHADPTLRRTGRLFGGLIEDVKRKAPFYLSDFKDAIHVQCFASFFFLYFACLTPIITFGGLLVQATGGYLGAIESILSGTIVGVVYSLFSGQPLTIMGSTGPVLVFESIVYNICERMRWDYLPFRLWIGVWIAAYLFLMVAFDLSALVRYITRFTEESFAALIALIFMVEAFKKLFLIVDYYPIDTRWNIDMIKNRTCECF----PRNATAMDAFFQKNNKPSNVYMPPMLYPVPLNSSVIDIVNNIDWQNISNYHFTWDYKKYRLICTKWGGIWTGSGCG--NYFIPDVFFFSCLLFIGTFVLSYGLKMMRNAQFFPNWVRSLISDFAVMIAISSMTLLDWSLGFHTPKLNVPAKFEPTLGYKMRGWVIPALGKNPWWTIIIAMGPALLAVILIFMDQQITAVIVNRKENKLKKGSGYHXXXXXXXXXXXXXXXXGIPWFVAATVLSINHVMSLKKESENTAPGERPVFLGCREQRVTGTIIFLVIGLSVFLTPLLKRIPMAVLYGVFLFMGVASLKGVQLMQRISLFFMPAKYQPDYIFLRYVPLRRVHXXXXXXXXXXXXXXXXXXXNVMSICFPIMVLALCFVRKGLEYLFTYNELKWLDDIMPNHKKPPQDDNENDIEKCGSTELIKMTETNLEFNSSTNKVIRSNDSGINISEEMGKTAIWKQL 3535
            +E ++DRG       TH+     E ED    R L+IGVH+P     + + +R R      + +  ++D   E   +     T PSQ V F+LG ED+DEE   H+LF E+DE+   +  + EW+ETARW+KFEEDVE+GGERWSKP+VA+LSL+SLFE+R+CI +   + ++ AN  E I +++L++ VS  +++ D R +V E L ++H H ++++  +     ++P++RS ADIGKK S                       D N+ Q    +S+ +   +KN +  +    D     K DLHF KKIP GAE SNI+VGE +FL++ VV F+RL  AV+L  L EVP+PTRF+F++LGP G   + HEIGRS+ATLM+D+VFHDVAYKA++ +DL++GIDEFL   TVLPP EWDPSIRIEPPK+ P    RK+P++PNG  A   A   G                             H+ P L+RTGR+FGGLI D+KRKAP++ SDF+DA  +QC ASF FLY AC++P+ITFGGLL +AT G + AIES+   ++ G+ YSLF GQPLTI+GSTGPVLVFE I++  C+     YL  R  IG+W A    ++VA D S+LV YITRFTEE+FA+LI +IF+ EA +KLF + + YPI+   +++++   +C C     P N T       K  + SN+             S  DI+    W+N++              C    G + G  CG  + ++PDV F+S +LF  T  LS  LK  + +++FP  VRS++SDFAV + I  M L+D+++G  +PKL VP+ F+PT     RGW +  LG NPWWT+I A+ PALL  ILIFMDQQITAVI+NRKE+KLKKG GYHLDLL+VA+++ V SI+G+PWFVAATVLSI HV SLK ESE +APGE+P FLG REQRVTG +IF+++G SVF+T +LK IPM VLYGVFL+MG +SLKG+Q   RI LF+MPAK+QPD+I+LR+VPLR+VHLFTIIQ+  L LLW+IK     +I FP+MVLAL FVRK ++ LFT  EL WLDD+MP  KK   +D E + E+   + L    E  ++     +   R + S INIS+EM KTA+W+ L
Sbjct:   20 EEAVVDRGGTRSILKTHF-----EKEDLEGHRTLFIGVHVP--LGGRKSHRRHRHRGHKHRKRDRERDSGLEDGRESPSFDT-PSQRVQFILGTEDDDEEHIPHDLFTELDEICWREGEDAEWRETARWLKFEEDVEDGGERWSKPYVATLSLHSLFELRSCILNGTVLLDMHANTLEEIADMVLDQQVSSGQLNEDVRHRVHEALMKQHHHQNQKKLTN-----RIPIVRSFADIGKKQSEP------------------NSMDKNAGQVVSPQSAPACVENKNDVSRENSTVD---FSKVDLHFMKKIPPGAEASNILVGELEFLDRTVVAFVRLSPAVLLQGLAEVPIPTRFLFILLGPLGKGQQYHEIGRSIATLMTDEVFHDVAYKAKDRNDLVSGIDEFLDQVTVLPPGEWDPSIRIEPPKNVPSQEKRKIPAVPNGTAAHGEAEPHG----------------------------GHSGPELQRTGRIFGGLILDIKRKAPYFWSDFRDAFSLQCLASFLFLYCACMSPVITFGGLLGEATEGRISAIESLFGASMTGIAYSLFGGQPLTILGSTGPVLVFEKILFKFCKEYGLSYLSLRASIGLWTATLCIILVATDASSLVCYITRFTEEAFASLICIIFIYEALEKLFELSEAYPINMHNDLELLTQYSCNCVEPHNPSNGTL------KEWRESNI-------------SASDII----WENLTVSE-----------CKSLHGEYVGRACGHDHPYVPDVLFWSVILFFSTVTLSATLKQFKTSRYFPTKVRSIVSDFAVFLTILCMVLIDYAIGIPSPKLQVPSVFKPT--RDDRGWFVTPLGPNPWWTVIAAIIPALLCTILIFMDQQITAVIINRKEHKLKKGCGYHLDLLMVAVMLGVCSIMGLPWFVAATVLSITHVNSLKLESECSAPGEQPKFLGIREQRVTGLMIFILMGSSVFMTSILKFIPMPVLYGVFLYMGASSLKGIQFFDRIKLFWMPAKHQPDFIYLRHVPLRKVHLFTIIQMSCLGLLWIIKVSRA-AIVFPMMVLALVFVRKLMDLLFTKRELSWLDDLMPESKKKKLEDAEKEEEQ---SMLAMEDEGTVQLPLEGH--YRDDPSVINISDEMSKTALWRNL 1067          
BLAST of slc4a-1 vs. Ensembl Human
Match: SLC4A10 (solute carrier family 4 member 10 [Source:HGNC Symbol;Acc:HGNC:13811])

HSP 1 Score: 942.954 bits (2436), Expect = 0.000e+0
Identity = 545/1152 (47.31%), Postives = 739/1152 (64.15%), Query Frame = 2
Query:  125 DEPILDRG----FQFTHYHPSEDEIEDHRSQRALYIGVHMPPDXXXXXXXXXXXXXXXXXXXXXDKKDYLTEIAEDDTEKATDPSQHVMFLLG-EDEDEE--THNLFCEMDELRLDDEGEPEWKETARWIKFEEDVEEGGERWSKPHVASLSLYSLFEVRNCITSAVNMFNVEANNFETIIEIILNKIVSEKKISPDQREKVKEMLQRKHVHLHERRHKSNAKGSQLPLIRSLADIGKKYSSKEVDKVQLQRRNSDYPTKFTRFDANXXXXXXXXXXXXXYVDKNRIDVDQCGSDNLASQKFDLHFFKKIPLGAETSNIMVGETDFLNQMVVVFIRLKEAVILGELTEVPVPTRFVFVMLGPQGSAVKNHEIGRSMATLMSDDVFHDVAYKARNLDDLLAGIDEFLSNCTVLPPAEWDPSIRIEPPKSGPIA--RKVPSMPNGAQALLTASGDGRXXXXXXXXXXXXXXASVVNKLQPVEEESHADPTLRRTGRLFGGLIEDVKRKAPFYLSDFKDAIHVQCFASFFFLYFACLTPIITFGGLLVQATGGYLGAIESILSGTIVGVVYSLFSGQPLTIMGSTGPVLVFESIVYNICERMRWDYLPFRLWIGVWIAAYLFLMVAFDLSALVRYITRFTEESFAALIALIFMVEAFKKLFLIVDYYPIDTRWNIDMIKNRTCECF----PRNATAMDAFFQKNNKPSNVYMPPMLYPVPLNSSVIDIVNNIDWQNISNYHFTWDYKKYRLICTKWGGIWTGSGCG--NYFIPDVFFFSCLLFIGTFVLSYGLKMMRNAQFFPNWVRSLISDFAVMIAISSMTLLDWSLGFHTPKLNVPAKFEPTLGYKMRGWVIPALGKNPWWTIIIAMGPALLAVILIFMDQQITAVIVNRKENKLKKGSGYHXXXXXXXXXXXXXXXXGIPWFVAATVLSINHVMSLKKESENTAPGERPVFLGCREQRVTGTIIFLVIGLSVFLTPLLKRIPMAVLYGVFLFMGVASLKGVQLMQRISLFFMPAKYQPDYIFLRYVPLRRVHXXXXXXXXXXXXXXXXXXXNVMSICFPIMVLALCFVRKGLEYLFTYNELKWLDDIMPNHKKPPQDDNENDIEKCGSTELIKMTETNLEFNSSTNKVIRSNDSGINISEEMGKTAIWKQL 3535
            +E ++DRG       TH+     E ED    R L+IGVH+P     + + +R R      + +  ++D   E   +     T PSQ V F+LG ED+DEE   H+LF E+DE+   +  + EW+ETARW+KFEEDVE+GGERWSKP+VA+LSL+SLFE+R+CI +   + ++ AN  E I +++L++ VS  +++ D R +V E L ++H H ++++  +     ++P++RS ADIGKK S                       D N+ Q    +S+ +   +KN +  +    D     K DLHF KKIP GAE SNI+VGE +FL++ VV F+RL  AV+L  L EVP+PTRF+F++LGP G   + HEIGRS+ATLM+D+VFHDVAYKA++ +DL++GIDEFL   TVLPP EWDPSIRIEPPK+ P    RK+P++PNG  A   A   G                             H+ P L+RTGR+FGGLI D+KRKAP++ SDF+DA  +QC ASF FLY AC++P+ITFGGLL +AT G + AIES+   ++ G+ YSLF GQPLTI+GSTGPVLVFE I++  C+     YL  R  IG+W A    ++VA D S+LV YITRFTEE+FA+LI +IF+ EA +KLF + + YPI+   +++++   +C C     P N T       K  + SN+             S  DI+    W+N++              C    G + G  CG  + ++PDV F+S +LF  T  LS  LK  + +++FP  VRS++SDFAV + I  M L+D+++G  +PKL VP+ F+PT     RGW +  LG NPWWT+I A+ PALL  ILIFMDQQITAVI+NRKE+KLKKG GYHLDLL+VA+++ V SI+G+PWFVAATVLSI HV SLK ESE +APGE+P FLG REQRVTG +IF+++G SVF+T +LK IPM VLYGVFL+MG +SLKG+Q   RI LF+MPAK+QPD+I+LR+VPLR+VHLFTIIQ+  L LLW+IK     +I FP+MVLAL FVRK ++ LFT  EL WLDD+MP  KK   +D E + E+   + L    E  ++     +   R + S INIS+EM KTA+W+ L
Sbjct:   31 EEAVVDRGGTRSILKTHF-----EKEDLEGHRTLFIGVHVP--LGGRKSHRRHRHRGHKHRKRDRERDSGLEDGRESPSFDT-PSQRVQFILGTEDDDEEHIPHDLFTELDEICWREGEDAEWRETARWLKFEEDVEDGGERWSKPYVATLSLHSLFELRSCILNGTVLLDMHANTLEEIADMVLDQQVSSGQLNEDVRHRVHEALMKQHHHQNQKKLTN-----RIPIVRSFADIGKKQSEP------------------NSMDKNAGQVVSPQSAPACVENKNDVSRENSTVD---FSKVDLHFMKKIPPGAEASNILVGELEFLDRTVVAFVRLSPAVLLQGLAEVPIPTRFLFILLGPLGKGQQYHEIGRSIATLMTDEVFHDVAYKAKDRNDLVSGIDEFLDQVTVLPPGEWDPSIRIEPPKNVPSQEKRKIPAVPNGTAAHGEAEPHG----------------------------GHSGPELQRTGRIFGGLILDIKRKAPYFWSDFRDAFSLQCLASFLFLYCACMSPVITFGGLLGEATEGRISAIESLFGASMTGIAYSLFGGQPLTILGSTGPVLVFEKILFKFCKEYGLSYLSLRASIGLWTATLCIILVATDASSLVCYITRFTEEAFASLICIIFIYEALEKLFELSEAYPINMHNDLELLTQYSCNCVEPHNPSNGTL------KEWRESNI-------------SASDII----WENLTVSE-----------CKSLHGEYVGRACGHDHPYVPDVLFWSVILFFSTVTLSATLKQFKTSRYFPTKVRSIVSDFAVFLTILCMVLIDYAIGIPSPKLQVPSVFKPT--RDDRGWFVTPLGPNPWWTVIAAIIPALLCTILIFMDQQITAVIINRKEHKLKKGCGYHLDLLMVAVMLGVCSIMGLPWFVAATVLSITHVNSLKLESECSAPGEQPKFLGIREQRVTGLMIFILMGSSVFMTSILKFIPMPVLYGVFLYMGASSLKGIQFFDRIKLFWMPAKHQPDFIYLRHVPLRKVHLFTIIQMSCLGLLWIIKVSRA-AIVFPMMVLALVFVRKLMDLLFTKRELSWLDDLMPESKKKKLEDAEKEEEQ---SMLAMEDEGTVQLPLEGH--YRDDPSVINISDEMSKTALWRNL 1078          
BLAST of slc4a-1 vs. Ensembl Human
Match: SLC4A10 (solute carrier family 4 member 10 [Source:HGNC Symbol;Acc:HGNC:13811])

HSP 1 Score: 942.954 bits (2436), Expect = 0.000e+0
Identity = 545/1152 (47.31%), Postives = 739/1152 (64.15%), Query Frame = 2
Query:  125 DEPILDRG----FQFTHYHPSEDEIEDHRSQRALYIGVHMPPDXXXXXXXXXXXXXXXXXXXXXDKKDYLTEIAEDDTEKATDPSQHVMFLLG-EDEDEE--THNLFCEMDELRLDDEGEPEWKETARWIKFEEDVEEGGERWSKPHVASLSLYSLFEVRNCITSAVNMFNVEANNFETIIEIILNKIVSEKKISPDQREKVKEMLQRKHVHLHERRHKSNAKGSQLPLIRSLADIGKKYSSKEVDKVQLQRRNSDYPTKFTRFDANXXXXXXXXXXXXXYVDKNRIDVDQCGSDNLASQKFDLHFFKKIPLGAETSNIMVGETDFLNQMVVVFIRLKEAVILGELTEVPVPTRFVFVMLGPQGSAVKNHEIGRSMATLMSDDVFHDVAYKARNLDDLLAGIDEFLSNCTVLPPAEWDPSIRIEPPKSGPIA--RKVPSMPNGAQALLTASGDGRXXXXXXXXXXXXXXASVVNKLQPVEEESHADPTLRRTGRLFGGLIEDVKRKAPFYLSDFKDAIHVQCFASFFFLYFACLTPIITFGGLLVQATGGYLGAIESILSGTIVGVVYSLFSGQPLTIMGSTGPVLVFESIVYNICERMRWDYLPFRLWIGVWIAAYLFLMVAFDLSALVRYITRFTEESFAALIALIFMVEAFKKLFLIVDYYPIDTRWNIDMIKNRTCECF----PRNATAMDAFFQKNNKPSNVYMPPMLYPVPLNSSVIDIVNNIDWQNISNYHFTWDYKKYRLICTKWGGIWTGSGCG--NYFIPDVFFFSCLLFIGTFVLSYGLKMMRNAQFFPNWVRSLISDFAVMIAISSMTLLDWSLGFHTPKLNVPAKFEPTLGYKMRGWVIPALGKNPWWTIIIAMGPALLAVILIFMDQQITAVIVNRKENKLKKGSGYHXXXXXXXXXXXXXXXXGIPWFVAATVLSINHVMSLKKESENTAPGERPVFLGCREQRVTGTIIFLVIGLSVFLTPLLKRIPMAVLYGVFLFMGVASLKGVQLMQRISLFFMPAKYQPDYIFLRYVPLRRVHXXXXXXXXXXXXXXXXXXXNVMSICFPIMVLALCFVRKGLEYLFTYNELKWLDDIMPNHKKPPQDDNENDIEKCGSTELIKMTETNLEFNSSTNKVIRSNDSGINISEEMGKTAIWKQL 3535
            +E ++DRG       TH+     E ED    R L+IGVH+P     + + +R R      + +  ++D   E   +     T PSQ V F+LG ED+DEE   H+LF E+DE+   +  + EW+ETARW+KFEEDVE+GGERWSKP+VA+LSL+SLFE+R+CI +   + ++ AN  E I +++L++ VS  +++ D R +V E L ++H H ++++  +     ++P++RS ADIGKK S                       D N+ Q    +S+ +   +KN +  +    D     K DLHF KKIP GAE SNI+VGE +FL++ VV F+RL  AV+L  L EVP+PTRF+F++LGP G   + HEIGRS+ATLM+D+VFHDVAYKA++ +DL++GIDEFL   TVLPP EWDPSIRIEPPK+ P    RK+P++PNG  A   A   G                             H+ P L+RTGR+FGGLI D+KRKAP++ SDF+DA  +QC ASF FLY AC++P+ITFGGLL +AT G + AIES+   ++ G+ YSLF GQPLTI+GSTGPVLVFE I++  C+     YL  R  IG+W A    ++VA D S+LV YITRFTEE+FA+LI +IF+ EA +KLF + + YPI+   +++++   +C C     P N T       K  + SN+             S  DI+    W+N++              C    G + G  CG  + ++PDV F+S +LF  T  LS  LK  + +++FP  VRS++SDFAV + I  M L+D+++G  +PKL VP+ F+PT     RGW +  LG NPWWT+I A+ PALL  ILIFMDQQITAVI+NRKE+KLKKG GYHLDLL+VA+++ V SI+G+PWFVAATVLSI HV SLK ESE +APGE+P FLG REQRVTG +IF+++G SVF+T +LK IPM VLYGVFL+MG +SLKG+Q   RI LF+MPAK+QPD+I+LR+VPLR+VHLFTIIQ+  L LLW+IK     +I FP+MVLAL FVRK ++ LFT  EL WLDD+MP  KK   +D E + E+   + L    E  ++     +   R + S INIS+EM KTA+W+ L
Sbjct:   20 EEAVVDRGGTRSILKTHF-----EKEDLEGHRTLFIGVHVP--LGGRKSHRRHRHRGHKHRKRDRERDSGLEDGRESPSFDT-PSQRVQFILGTEDDDEEHIPHDLFTELDEICWREGEDAEWRETARWLKFEEDVEDGGERWSKPYVATLSLHSLFELRSCILNGTVLLDMHANTLEEIADMVLDQQVSSGQLNEDVRHRVHEALMKQHHHQNQKKLTN-----RIPIVRSFADIGKKQSEP------------------NSMDKNAGQVVSPQSAPACVENKNDVSRENSTVD---FSKVDLHFMKKIPPGAEASNILVGELEFLDRTVVAFVRLSPAVLLQGLAEVPIPTRFLFILLGPLGKGQQYHEIGRSIATLMTDEVFHDVAYKAKDRNDLVSGIDEFLDQVTVLPPGEWDPSIRIEPPKNVPSQEKRKIPAVPNGTAAHGEAEPHG----------------------------GHSGPELQRTGRIFGGLILDIKRKAPYFWSDFRDAFSLQCLASFLFLYCACMSPVITFGGLLGEATEGRISAIESLFGASMTGIAYSLFGGQPLTILGSTGPVLVFEKILFKFCKEYGLSYLSLRASIGLWTATLCIILVATDASSLVCYITRFTEEAFASLICIIFIYEALEKLFELSEAYPINMHNDLELLTQYSCNCVEPHNPSNGTL------KEWRESNI-------------SASDII----WENLTVSE-----------CKSLHGEYVGRACGHDHPYVPDVLFWSVILFFSTVTLSATLKQFKTSRYFPTKVRSIVSDFAVFLTILCMVLIDYAIGIPSPKLQVPSVFKPT--RDDRGWFVTPLGPNPWWTVIAAIIPALLCTILIFMDQQITAVIINRKEHKLKKGCGYHLDLLMVAVMLGVCSIMGLPWFVAATVLSITHVNSLKLESECSAPGEQPKFLGIREQRVTGLMIFILMGSSVFMTSILKFIPMPVLYGVFLYMGASSLKGIQFFDRIKLFWMPAKHQPDFIYLRHVPLRKVHLFTIIQMSCLGLLWIIKVSRA-AIVFPMMVLALVFVRKLMDLLFTKRELSWLDDLMPESKKKKLEDAEKEEEQ---SMLAMEDEGTVQLPLEGH--YRDDPSVINISDEMSKTALWRNL 1067          
BLAST of slc4a-1 vs. Ensembl Human
Match: SLC4A10 (solute carrier family 4 member 10 [Source:HGNC Symbol;Acc:HGNC:13811])

HSP 1 Score: 939.488 bits (2427), Expect = 0.000e+0
Identity = 544/1161 (46.86%), Postives = 741/1161 (63.82%), Query Frame = 2
Query:  125 DEPILDRG----FQFTHYHPSEDEIEDHRSQRALYIGVHMPPDXXXXXXXXXXXXXXXXXXXXXDKKDYLTEIAEDDTEKATDPSQHVMFLLG-EDEDEE--THNLFCEMDELRLDDEGEPEWKETARWIKFEEDVEEGGERWSKPHVASLSLYSLFEVRNCITSAVNMFNVEANNFETIIEIILNKIVSEKKISPDQREKVKEMLQRKHVHLHERRHKSNAKGSQLPLIRSLADIGKKYSS-KEVDKVQLQRRNSDYPTKFTRFDANXXXXXXXXXXXXXYVDKNRIDVDQCGSD--------NLASQKFDLHFFKKIPLGAETSNIMVGETDFLNQMVVVFIRLKEAVILGELTEVPVPTRFVFVMLGPQGSAVKNHEIGRSMATLMSDDVFHDVAYKARNLDDLLAGIDEFLSNCTVLPPAEWDPSIRIEPPKSGPIA--RKVPSMPNGAQALLTASGDGRXXXXXXXXXXXXXXASVVNKLQPVEEESHADPTLRRTGRLFGGLIEDVKRKAPFYLSDFKDAIHVQCFASFFFLYFACLTPIITFGGLLVQATGGYLGAIESILSGTIVGVVYSLFSGQPLTIMGSTGPVLVFESIVYNICERMRWDYLPFRLWIGVWIAAYLFLMVAFDLSALVRYITRFTEESFAALIALIFMVEAFKKLFLIVDYYPIDTRWNIDMIKNRTCECF----PRNATAMDAFFQKNNKPSNVYMPPMLYPVPLNSSVIDIVNNIDWQNISNYHFTWDYKKYRLICTKWGGIWTGSGCG--NYFIPDVFFFSCLLFIGTFVLSYGLKMMRNAQFFPNWVRSLISDFAVMIAISSMTLLDWSLGFHTPKLNVPAKFEPTLGYKMRGWVIPALGKNPWWTIIIAMGPALLAVILIFMDQQITAVIVNRKENKLKKGSGYHXXXXXXXXXXXXXXXXGIPWFVAATVLSINHVMSLKKESENTAPGERPVFLGCREQRVTGTIIFLVIGLSVFLTPLLKRIPMAVLYGVFLFMGVASLKGVQLMQRISLFFMPAKYQPDYIFLRYVPLRRVHXXXXXXXXXXXXXXXXXXXNVMSICFPIMVLALCFVRKGLEYLFTYNELKWLDDIMPNHKKPPQDDNENDIEKCGSTELIKMTETNLEFNSSTNKVIRSNDSGINISEEMGKTAIWKQL 3535
            +E ++DRG       TH+     E ED    R L+IGVH+P     + + +R R      + +  ++D   E   +     T PSQ V F+LG ED+DEE   H+LF E+DE+   +  + EW+ETARW+KFEEDVE+GGERWSKP+VA+LSL+SLFE+R+CI +   + ++ AN  E I +++L++ VS  +++ D R +V E L ++H H ++++  +     ++P++RS ADIGKK S    +DK   Q  +            + S+ +     S     + +     CG          +   ++ DLHF KKIP GAE SNI+VGE +FL++ VV F+RL  AV+L  L EVP+PTRF+F++LGP G   + HEIGRS+ATLM+D+VFHDVAYKA++ +DL++GIDEFL   TVLPP EWDPSIRIEPPK+ P    RK+P++PNG  A   A   G                             H+ P L+RTGR+FGGLI D+KRKAP++ SDF+DA  +QC ASF FLY AC++P+ITFGGLL +AT G + AIES+   ++ G+ YSLF GQPLTI+GSTGPVLVFE I++  C+     YL  R  IG+W A    ++VA D S+LV YITRFTEE+FA+LI +IF+ EA +KLF + + YPI+   +++++   +C C     P N T       K  + SN+             S  DI+    W+N++              C    G + G  CG  + ++PDV F+S +LF  T  LS  LK  + +++FP  VRS++SDFAV + I  M L+D+++G  +PKL VP+ F+PT     RGW +  LG NPWWT+I A+ PALL  ILIFMDQQITAVI+NRKE+KLKKG GYHLDLL+VA+++ V SI+G+PWFVAATVLSI HV SLK ESE +APGE+P FLG REQRVTG +IF+++G SVF+T +LK IPM VLYGVFL+MG +SLKG+Q   RI LF+MPAK+QPD+I+LR+VPLR+VHLFTIIQ+  L LLW+IK     +I FP+MVLAL FVRK ++ LFT  EL WLDD+MP  KK   +D E + E+   + L    E  ++     +   R + S INIS+EM KTA+W+ L
Sbjct:   20 EEAVVDRGGTRSILKTHF-----EKEDLEGHRTLFIGVHVP--LGGRKSHRRHRHRGHKHRKRDRERDSGLEDGRESPSFDT-PSQRVQFILGTEDDDEEHIPHDLFTELDEICWREGEDAEWRETARWLKFEEDVEDGGERWSKPYVATLSLHSLFELRSCILNGTVLLDMHANTLEEIADMVLDQQVSSGQLNEDVRHRVHEALMKQHHHQNQKKLTN-----RIPIVRSFADIGKKQSEPNSMDKNAGQVVSPQSAPACVENKNDVSRENSTVDFSKGLGGQQKGHTSPCGMKQRHEKGPPHQQEREVDLHFMKKIPPGAEASNILVGELEFLDRTVVAFVRLSPAVLLQGLAEVPIPTRFLFILLGPLGKGQQYHEIGRSIATLMTDEVFHDVAYKAKDRNDLVSGIDEFLDQVTVLPPGEWDPSIRIEPPKNVPSQEKRKIPAVPNGTAAHGEAEPHG----------------------------GHSGPELQRTGRIFGGLILDIKRKAPYFWSDFRDAFSLQCLASFLFLYCACMSPVITFGGLLGEATEGRISAIESLFGASMTGIAYSLFGGQPLTILGSTGPVLVFEKILFKFCKEYGLSYLSLRASIGLWTATLCIILVATDASSLVCYITRFTEEAFASLICIIFIYEALEKLFELSEAYPINMHNDLELLTQYSCNCVEPHNPSNGTL------KEWRESNI-------------SASDII----WENLTVSE-----------CKSLHGEYVGRACGHDHPYVPDVLFWSVILFFSTVTLSATLKQFKTSRYFPTKVRSIVSDFAVFLTILCMVLIDYAIGIPSPKLQVPSVFKPT--RDDRGWFVTPLGPNPWWTVIAAIIPALLCTILIFMDQQITAVIINRKEHKLKKGCGYHLDLLMVAVMLGVCSIMGLPWFVAATVLSITHVNSLKLESECSAPGEQPKFLGIREQRVTGLMIFILMGSSVFMTSILKFIPMPVLYGVFLYMGASSLKGIQFFDRIKLFWMPAKHQPDFIYLRHVPLRKVHLFTIIQMSCLGLLWIIKVSRA-AIVFPMMVLALVFVRKLMDLLFTKRELSWLDDLMPESKKKKLEDAEKEEEQ---SMLAMEDEGTVQLPLEGH--YRDDPSVINISDEMSKTALWRNL 1097          
BLAST of slc4a-1 vs. Ensembl Human
Match: SLC4A7 (solute carrier family 4 member 7 [Source:HGNC Symbol;Acc:HGNC:11033])

HSP 1 Score: 932.169 bits (2408), Expect = 0.000e+0
Identity = 540/1151 (46.92%), Postives = 728/1151 (63.25%), Query Frame = 2
Query:  182 EIEDHRSQRALYIGVHMPPDXXXXXXXXXXXXXXXXXXXXXDKKDYLTEIAEDDTEKAT--DPSQHVMFLLG-EDEDEE--THNLFCEMDELRLDDEGEPEWKETARWIKFEEDVEEGGERWSKPHVASLSLYSLFEVRNCITSAVNMFNVEANNFETIIEIILNKIVSEKKISPDQREKVKEMLQRKHVHLHERRHKSNAKGSQLPLIRSLADIGKKYSSKEVDKVQLQRRNS--DYPTKFTRFDANXXXXXXXXXXXXXYVDKNRIDVDQCGSDNLASQKFDLHFFKKIPLGAETSNIMVGETDFLNQMVVVFIRLKEAVILGELTEVPVPTRFVFVMLGPQGSAVKNHEIGRSMATLMSDDVFHDVAYKARNLDDLLAGIDEFLSNCTVLPPAEWDPSIRIEPPKSGPIA--RKVPSMPNGAQALLTASGDGRXXXXXXXXXXXXXXASVVNKLQPVEEESHADPTLRRTGRLFGGLIEDVKRKAPFYLSDFKDAIHVQCFASFFFLYFACLTPIITFGGLLVQATGGYLGAIESILSGTIVGVVYSLFSGQPLTIMGSTGPVLVFESIVYNICERMRWDYLPFRLWIGVWIAAYLFLMVAFDLSALVRYITRFTEESFAALIALIFMVEAFKKLFLIVDYYPIDTRWNIDMIKNRTCECF--PRNATAMDAFFQKNNKPSNVYMPPMLYPVPLNSSVIDIVNNIDWQNISNYHFTWDYKKYRLICTKWGGIWTGSGCGNY--FIPDVFFFSCLLFIGTFVLSYGLKMMRNAQFFPNWVRSLISDFAVMIAISSMTLLDWSLGFHTPKLNVPAKFEPTLGYKMRGWVIPALGKNPWWTIIIAMGPALLAVILIFMDQQITAVIVNRKENKLKKGSGYHXXXXXXXXXXXXXXXXGIPWFVAATVLSINHVMSLKKESENTAPGERPVFLGCREQRVTGTIIFLVIGLSVFLTPLLKRIPMAVLYGVFLFMGVASLKGVQLMQRISLFFMPAKYQPDYIFLRYVPLRRVHXXXXXXXXXXXXXXXXXXXNVMSICFPIMVLALCFVRKGLEYLFTYNELKWLDDIMPNH----------------KKPPQDDNENDIEKCGSTELIKMTETNLEFNSSTNKVIRSNDSGINISEEMGKTAIWKQLSGGT 3547
            E E+  S RA+YIGVH+P  +  +   + R      ++ +  + D      ED  E  +   PSQ V F+LG ED+DEE   H+LF EMDEL   D  E EWKETARW+KFEEDVE+GG+RWSKP+VA+LSL+SLFE+R+CI +   M ++ A+  + I +++L+ +++  ++    RE V+E L ++H H +E+R  S     ++PL+RS ADIGKK+S        L  RN     P        NS    I  + S    + + +D            K D++F +KIP GAE SN++VGE DFL + ++ F+RL  AV+L  LTEVPVPTRF+F++LGP G A + HEIGRS+ATLM+D++FHDVAYKA++ +DLL+GIDEFL   TVLPP EWDPSIRIEPPKS P    RK+P   NG+   L  +                          P E   HA P L+RTGRLFGGLI D+KRKAPF+LSDFKDA+ +QC AS  FLY AC++P+ITFGGLL +AT G + AIES+   ++ G+ YSLF+GQPLTI+GSTGPVLVFE I+Y  C   +  YL  R  IG+W +    ++VA D S+LV YITRFTEE+FAALI +IF+ EA +KLF + + Y  +   N+D + + +C C   P  +    A ++K+N  +                     +NI W+N++              C K  G++ GS CG++  +IPDV F+  +LF  TF LS  LK  +  ++FP  VRS ISDFAV + I  M  +D+ +G  +PKL+VP KFEPT  +  RGW+I  LG NPWWT++IA  PALL  ILIFMDQQITAVI+NRKE+KLKKG+GYHLDLL+V +++ V S++G+PWFVAATVLSI+HV SLK ESE +APGE+P FLG REQRVTG +IF+++GLSVF+T +LK IPM VLYGVFL+MGV+SLKG+QL  RI LF MPAK+QPD I+LRYVPL +VH    +  +  ++L  +  ++  ++ FP+MVLAL FVRK ++  FT  EL WLDD+MP                  ++  QDD++          L+++    L+++         + S +NIS+EM KTA WK LS  T
Sbjct:   38 EKEELESHRAVYIGVHVPFSKESRRRHRHRGHKHHHRRRKDKESD-----KEDGRESPSYDTPSQRVQFILGTEDDDEEHIPHDLFTEMDELCYRDGEEYEWKETARWLKFEEDVEDGGDRWSKPYVATLSLHSLFELRSCILNGTVMLDMRASTLDEIADMVLDNMIASGQLDESIRENVREALLKRHHHQNEKRFTS-----RIPLVRSFADIGKKHSDP-----HLLERNGILASPQSAPGNLDNSKSGEIKGNGSGGSRENSTVDF----------SKVDMNFMRKIPTGAEASNVLVGEVDFLERPIIAFVRLAPAVLLTGLTEVPVPTRFLFLLLGPAGKAPQYHEIGRSIATLMTDEIFHDVAYKAKDRNDLLSGIDEFLDQVTVLPPGEWDPSIRIEPPKSVPSQEKRKIPVFHNGSTPTLGET--------------------------PKEAAHHAGPELQRTGRLFGGLILDIKRKAPFFLSDFKDALSLQCLASILFLYCACMSPVITFGGLLGEATEGRISAIESLFGASLTGIAYSLFAGQPLTILGSTGPVLVFEKILYKFCRDYQLSYLSLRTSIGLWTSFLCIVLVATDASSLVCYITRFTEEAFAALICIIFIYEALEKLFDLGETYAFNMHNNLDKLTSYSCVCTEPPNPSNETLAQWKKDNITA---------------------HNISWRNLTVSE-----------CKKLRGVFLGSACGHHGPYIPDVLFWCVILFFTTFFLSSFLKQFKTKRYFPTKVRSTISDFAVFLTIVIMVTIDYLVGVPSPKLHVPEKFEPT--HPERGWIISPLGDNPWWTLLIAAIPALLCTILIFMDQQITAVIINRKEHKLKKGAGYHLDLLMVGVMLGVCSVMGLPWFVAATVLSISHVNSLKVESECSAPGEQPKFLGIREQRVTGLMIFILMGLSVFMTSVLKFIPMPVLYGVFLYMGVSSLKGIQLFDRIKLFGMPAKHQPDLIYLRYVPLWKVH-IFTVIQLTCLVLLWVIKVSAAAVVFPMMVLALVFVRKLMDLCFTKRELSWLDDLMPESKKKKEDDKKKKEKEEAERMLQDDDDTVHLPFEGGSLLQIPVKALKYS--------VDPSIVNISDEMAKTAQWKALSMNT 1094          
BLAST of slc4a-1 vs. Ensembl Celegans
Match: abts-1 (Anion exchange protein [Source:UniProtKB/TrEMBL;Acc:B3WFV9])

HSP 1 Score: 854.744 bits (2207), Expect = 0.000e+0
Identity = 506/1089 (46.46%), Postives = 680/1089 (62.44%), Query Frame = 2
Query:  362 PSQHVMFLLGEDEDEETHNLFCEMDELRLDDEGEPEWKETARWIKFEEDVEEGGERWSKPHVASLSLYSLFEVRNCITSAVNMFNVEANNFETIIEIILNKIVSEKKISPDQREKVKEMLQRKHVHLHERRHKSNA---KGSQLPLIRSLADIGKKYS-SKEVDKVQLQRRNSDYPTKFTRFDANXXXXXXXXXXXXXYVDKNRIDVDQCGSDNLASQKFDLHFFKKIPLGAETSNIMVGETDFLNQMVVVFIRLKEAVILGELTEVPVPTRFVFVMLGPQGSAVKNHEIGRSMATLMSDDVFHDVAYKARNLDDLLAGIDEFLSNCTVLPPAEWDPSIRIEPPKSGPIARKVPSMPNGAQALLTASGDGRXXXXXXXXXXXXXXASVVNKLQPVEEE---SHA-DPTLRRTGRLFGGLIEDVKRKAPFYLSDFKDAIHVQCFASFFFLYFACLTPIITFGGLLVQATGGYLGAIESILSGTIVGVVYSLFSGQPLTIMGSTGPVLVFESIVYNICERMRWDYLPFRLWIGVWIAAYLFLMVAFDLSALVRYITRFTEESFAALIALIFMVEAFKKLFLIVDYYPIDTRWNIDMIKNRTCECFP---RNATAMDAFFQKNNKPSNVYMPPMLYPVPLNSSVIDIVNNIDWQNISNYHFTWDYKKYRLICTKWGGIWTGSGCGNYFIPDVFFFSCLLFIGTFVLSYGLKMMRNAQFFPNWVRSLISDFAVMIAISSMTLLDWSLGFHTPKLNVPAKFEPTLGYKMRGWVIPALGKNPWWTIIIAMGPALLAVILIFMDQQITAVIVNRKENKLKKGSGYHXXXXXXXXXXXXXXXXGIPWFVAATVLSINHVMSLKKESENTAPGERPVFLGCREQRVTGTIIFLVIGLSVFLTPLLKRIPMAVLYGVFLFMGVASLKGVQLMQRISLFFMPAKYQPDYIFLRYVPLRRVHXXXXXXXXXXXXXXXXXXXNVMSICFPIMVLALCFVRKGLEYLFTYNELKWLDDIMPN-HKKPPQD-----------DNENDIEKCGSTELIKMTETNLEFNSSTNKVIR-------SNDSGINISEEMGKTAIWKQLS 3538
            P   VMFLL E E+  T  LF EM EL  +     EW+ETARW+KFEEDVE+GG RWSKPHVA+LSL+SLF++R+CI +   M ++   +  +I   ++  +     +  + RE+++E+L RKHVH +E+  K+ A   KG  L  +RS++DIGK +S  K + K++      + P       A S   + +   +   V K+ I  ++       S K +LHF KK+P G E SN+++GE DFL + +  FIRLK A  LG+LTEVPVPTRF+F++LGP G   +  EIGR++ATLM+D++FHDVAY AR++DDLL GIDEFL   TVLPP EWDP+IRIEPP   P   K   +  G + L+  S                     V K+  VEEE   SH  DP L+RTG+LFGGLI D+KRKAP ++SDF DA ++QC AS  F+YF  L PI+TFGGLL +AT   + A+E++  G + GV+Y  F+GQPLTI+GSTGPVLVFE+IV++ C R    YL FR W+ VW A  +FLMV  D SALV +ITRFTEESFA LIA+IF+ EA  KL  I     +   ++ D ++   C C P   + + + D         + + +     P+  N + ID        N+++             C   GG + G+ C  + + D    S LL +GTF L+  LK MRN+ +FP+ VR L+SDFAVMIAI+SMT +D  +G +TPKLNVP+ F PT  ++ RGW IP    N WWT  +A+ PALLA ILIFMDQQIT VIVNRKENKLKKG GYHLDLLV+++ IL+   LG+P +VAATVLSINH+ SLK ESE  APGE   F+G REQRVTG + FL+IGLSV  T +L RIPM VLYGVFL+MG+++L G+QL  R  L FMP KYQPD I++R+VP+R++HLFT  QI  L LLWVIK+I   SI FPIM++ +  +RK +E  FT  +LK+LDD MP+ H +  +D           + E D E   +   +K TE +L    ++  VI+            IN+++E+  + +WK ++
Sbjct:   26 PGTRVMFLLKEKEN--TPALFTEMGELNNE-----EWRETARWVKFEEDVEQGGNRWSKPHVATLSLHSLFQLRSCIMNGHFMNDLAETDIPSIFNAVIENLEKSGDLPSENREELREILLRKHVHQYEQAKKNGAGGEKGGFLSTVRSISDIGKSFSHGKNLSKIE---EKPEGPVTSQTAGAPSGSSNQLTLPTVESVPKD-ISSEE-------SSKGNLHFLKKLPAGVEASNVLIGEVDFLTRHICCFIRLKNANQLGDLTEVPVPTRFIFLLLGPTGHGQQYREIGRAIATLMADEIFHDVAYGARDVDDLLDGIDEFLDQVTVLPPGEWDPNIRIEPPSKLPSQEKRKQI--GQELLVEPSSHKH-----------------VKKV--VEEEEIHSHGDDPALKRTGKLFGGLILDIKRKAPHFVSDFTDAFNLQCLASICFMYFGLLAPIVTFGGLLEEATHQRMAAMENLFGGALCGVIYHFFAGQPLTIVGSTGPVLVFETIVFDFCHRFGIVYLSFRFWVHVWTAVIIFLMVVTDASALVSFITRFTEESFATLIAVIFIYEAIMKLVKIKGQLDM-INYSRDFVEGGFCSCVPPIGKPSVSPDH--------ARLVIKSTGLPIAFNDTFIDYTA----ANLTD-------------CRTIGGSFDGTTC--FPLYDKLLMSILLTVGTFFLATTLKKMRNSCYFPSSVRQLLSDFAVMIAIASMTFVDIFVGVNTPKLNVPSTFRPT--WEGRGWFIPPFDANEWWTAPLAILPALLACILIFMDQQITTVIVNRKENKLKKGCGYHLDLLVLSVSILMVGFLGLPIYVAATVLSINHINSLKVESECKAPGEVAQFVGVREQRVTGIVTFLIIGLSVLATNILGRIPMPVLYGVFLYMGISALGGIQLFDRTLLLFMPMKYQPDTIYIRHVPIRKIHLFTAFQIGCLALLWVIKSIKSTSILFPIMLVVMVAIRKMMEKAFTTTDLKYLDDPMPDFHLRKKEDAKRRQSEGEAVEIEFDNENQATIHAVK-TEAHLHIPMASGNVIKIPLAAIQEPSHSINLTKEVNNSGMWKHIT 1044          
BLAST of slc4a-1 vs. Ensembl Celegans
Match: abts-1 (Anion exchange protein [Source:UniProtKB/TrEMBL;Acc:B3WFV9])

HSP 1 Score: 853.973 bits (2205), Expect = 0.000e+0
Identity = 506/1089 (46.46%), Postives = 680/1089 (62.44%), Query Frame = 2
Query:  362 PSQHVMFLLGEDEDEETHNLFCEMDELRLDDEGEPEWKETARWIKFEEDVEEGGERWSKPHVASLSLYSLFEVRNCITSAVNMFNVEANNFETIIEIILNKIVSEKKISPDQREKVKEMLQRKHVHLHERRHKSNA---KGSQLPLIRSLADIGKKYS-SKEVDKVQLQRRNSDYPTKFTRFDANXXXXXXXXXXXXXYVDKNRIDVDQCGSDNLASQKFDLHFFKKIPLGAETSNIMVGETDFLNQMVVVFIRLKEAVILGELTEVPVPTRFVFVMLGPQGSAVKNHEIGRSMATLMSDDVFHDVAYKARNLDDLLAGIDEFLSNCTVLPPAEWDPSIRIEPPKSGPIARKVPSMPNGAQALLTASGDGRXXXXXXXXXXXXXXASVVNKLQPVEEE---SHA-DPTLRRTGRLFGGLIEDVKRKAPFYLSDFKDAIHVQCFASFFFLYFACLTPIITFGGLLVQATGGYLGAIESILSGTIVGVVYSLFSGQPLTIMGSTGPVLVFESIVYNICERMRWDYLPFRLWIGVWIAAYLFLMVAFDLSALVRYITRFTEESFAALIALIFMVEAFKKLFLIVDYYPIDTRWNIDMIKNRTCECFP---RNATAMDAFFQKNNKPSNVYMPPMLYPVPLNSSVIDIVNNIDWQNISNYHFTWDYKKYRLICTKWGGIWTGSGCGNYFIPDVFFFSCLLFIGTFVLSYGLKMMRNAQFFPNWVRSLISDFAVMIAISSMTLLDWSLGFHTPKLNVPAKFEPTLGYKMRGWVIPALGKNPWWTIIIAMGPALLAVILIFMDQQITAVIVNRKENKLKKGSGYHXXXXXXXXXXXXXXXXGIPWFVAATVLSINHVMSLKKESENTAPGERPVFLGCREQRVTGTIIFLVIGLSVFLTPLLKRIPMAVLYGVFLFMGVASLKGVQLMQRISLFFMPAKYQPDYIFLRYVPLRRVHXXXXXXXXXXXXXXXXXXXNVMSICFPIMVLALCFVRKGLEYLFTYNELKWLDDIMPN-HKKPPQD-----------DNENDIEKCGSTELIKMTETNLEFNSSTNKVIR-------SNDSGINISEEMGKTAIWKQLS 3538
            P   VMFLL E E+  T  LF EM EL  +     EW+ETARW+KFEEDVE+GG RWSKPHVA+LSL+SLF++R+CI +   M ++   +  +I   ++  +     +  + RE+++E+L RKHVH +E+  K+ A   KG  L  +RS++DIGK +S  K + K++      + P       A S   + +   +   V K+ I  ++       S K +LHF KK+P G E SN+++GE DFL + +  FIRLK A  LG+LTEVPVPTRF+F++LGP G   +  EIGR++ATLM+D++FHDVAY AR++DDLL GIDEFL   TVLPP EWDP+IRIEPP   P   K   +  G + L+  S                     V K+  VEEE   SH  DP L+RTG+LFGGLI D+KRKAP ++SDF DA ++QC AS  F+YF  L PI+TFGGLL +AT   + A+E++  G + GV+Y  F+GQPLTI+GSTGPVLVFE+IV++ C R    YL FR W+ VW A  +FLMV  D SALV +ITRFTEESFA LIA+IF+ EA  KL  I     +   ++ D ++   C C P   + + + D         + + +     P+  N + ID        N+++             C   GG + G+ C  + + D    S LL +GTF L+  LK MRN+ +FP+ VR L+SDFAVMIAI+SMT +D  +G +TPKLNVP+ F PT  ++ RGW IP    N WWT  +A+ PALLA ILIFMDQQIT VIVNRKENKLKKG GYHLDLLV+++ IL+   LG+P +VAATVLSINH+ SLK ESE  APGE   F+G REQRVTG + FL+IGLSV  T +L RIPM VLYGVFL+MG+++L G+QL  R  L FMP KYQPD I++R+VP+R++HLFT  QI  L LLWVIK+I   SI FPIM++ +  +RK +E  FT  +LK+LDD MP+ H +  +D           + E D E   +   +K TE +L    ++  VI+            IN+++E+  + +WK ++
Sbjct:   68 PGTRVMFLLKEKEN--TPALFTEMGELNNE-----EWRETARWVKFEEDVEQGGNRWSKPHVATLSLHSLFQLRSCIMNGHFMNDLAETDIPSIFNAVIENLEKSGDLPSENREELREILLRKHVHQYEQAKKNGAGGEKGGFLSTVRSISDIGKSFSHGKNLSKIE---EKPEGPVTSQTAGAPSGSSNQLTLPTVESVPKD-ISSEE-------SSKGNLHFLKKLPAGVEASNVLIGEVDFLTRHICCFIRLKNANQLGDLTEVPVPTRFIFLLLGPTGHGQQYREIGRAIATLMADEIFHDVAYGARDVDDLLDGIDEFLDQVTVLPPGEWDPNIRIEPPSKLPSQEKRKQI--GQELLVEPSSHKH-----------------VKKV--VEEEEIHSHGDDPALKRTGKLFGGLILDIKRKAPHFVSDFTDAFNLQCLASICFMYFGLLAPIVTFGGLLEEATHQRMAAMENLFGGALCGVIYHFFAGQPLTIVGSTGPVLVFETIVFDFCHRFGIVYLSFRFWVHVWTAVIIFLMVVTDASALVSFITRFTEESFATLIAVIFIYEAIMKLVKIKGQLDM-INYSRDFVEGGFCSCVPPIGKPSVSPDH--------ARLVIKSTGLPIAFNDTFIDYTA----ANLTD-------------CRTIGGSFDGTTC--FPLYDKLLMSILLTVGTFFLATTLKKMRNSCYFPSSVRQLLSDFAVMIAIASMTFVDIFVGVNTPKLNVPSTFRPT--WEGRGWFIPPFDANEWWTAPLAILPALLACILIFMDQQITTVIVNRKENKLKKGCGYHLDLLVLSVSILMVGFLGLPIYVAATVLSINHINSLKVESECKAPGEVAQFVGVREQRVTGIVTFLIIGLSVLATNILGRIPMPVLYGVFLYMGISALGGIQLFDRTLLLFMPMKYQPDTIYIRHVPIRKIHLFTAFQIGCLALLWVIKSIKSTSILFPIMLVVMVAIRKMMEKAFTTTDLKYLDDPMPDFHLRKKEDAKRRQSEGEAVEIEFDNENQATIHAVK-TEAHLHIPMASGNVIKIPLAAIQEPSHSINLTKEVNNSGMWKHIT 1086          
BLAST of slc4a-1 vs. Ensembl Celegans
Match: abts-1 (Anion exchange protein [Source:UniProtKB/TrEMBL;Acc:B3WFV9])

HSP 1 Score: 831.247 bits (2146), Expect = 0.000e+0
Identity = 506/1143 (44.27%), Postives = 680/1143 (59.49%), Query Frame = 2
Query:  362 PSQHVMFLLGEDEDEETHNLFCEMDELRLDDEGEPEWKETARWIKFEEDVEEGGERWSKPHVASLSLYSLFEVRNCITSAVNMFNVEANNFETIIEIILNKIVSEKKISPDQREKVKEMLQRKHVHLHE-----------------------------------------------------RRHKSNAKGSQ----LPLIRSLADIGKKYS-SKEVDKVQLQRRNSDYPTKFTRFDANXXXXXXXXXXXXXYVDKNRIDVDQCGSDNLASQKFDLHFFKKIPLGAETSNIMVGETDFLNQMVVVFIRLKEAVILGELTEVPVPTRFVFVMLGPQGSAVKNHEIGRSMATLMSDDVFHDVAYKARNLDDLLAGIDEFLSNCTVLPPAEWDPSIRIEPPKSGPIARKVPSMPNGAQALLTASGDGRXXXXXXXXXXXXXXASVVNKLQPVEEE---SHA-DPTLRRTGRLFGGLIEDVKRKAPFYLSDFKDAIHVQCFASFFFLYFACLTPIITFGGLLVQATGGYLGAIESILSGTIVGVVYSLFSGQPLTIMGSTGPVLVFESIVYNICERMRWDYLPFRLWIGVWIAAYLFLMVAFDLSALVRYITRFTEESFAALIALIFMVEAFKKLFLIVDYYPIDTRWNIDMIKNRTCECFP---RNATAMDAFFQKNNKPSNVYMPPMLYPVPLNSSVIDIVNNIDWQNISNYHFTWDYKKYRLICTKWGGIWTGSGCGNYFIPDVFFFSCLLFIGTFVLSYGLKMMRNAQFFPNWVRSLISDFAVMIAISSMTLLDWSLGFHTPKLNVPAKFEPTLGYKMRGWVIPALGKNPWWTIIIAMGPALLAVILIFMDQQITAVIVNRKENKLKKGSGYHXXXXXXXXXXXXXXXXGIPWFVAATVLSINHVMSLKKESENTAPGERPVFLGCREQRVTGTIIFLVIGLSVFLTPLLKRIPMAVLYGVFLFMGVASLKGVQLMQRISLFFMPAKYQPDYIFLRYVPLRRVHXXXXXXXXXXXXXXXXXXXNVMSICFPIMVLALCFVRKGLEYLFTYNELKWLDDIMPN-HKKPPQD-----------DNENDIEKCGSTELIKMTETNLEFNSSTNKVIR-------SNDSGINISEEMGKTAIWKQLS 3538
            P   VMFLL E E+  T  LF EM EL  +     EW+ETARW+KFEEDVE+GG RWSKPHVA+LSL+SLF++R+CI +   M ++   +  +I   ++  +     +  + RE+++E+L RKHVH +E                                                     R+ K N  G +    L  +RS++DIGK +S  K + K++      + P       A S   + +   +   V K+ I  ++       S K +LHF KK+P G E SN+++GE DFL + +  FIRLK A  LG+LTEVPVPTRF+F++LGP G   +  EIGR++ATLM+D++FHDVAY AR++DDLL GIDEFL   TVLPP EWDP+IRIEPP   P   K   +  G + L+  S                     V K+  VEEE   SH  DP L+RTG+LFGGLI D+KRKAP ++SDF DA ++QC AS  F+YF  L PI+TFGGLL +AT   + A+E++  G + GV+Y  F+GQPLTI+GSTGPVLVFE+IV++ C R    YL FR W+ VW A  +FLMV  D SALV +ITRFTEESFA LIA+IF+ EA  KL  I     +   ++ D ++   C C P   + + + D         + + +     P+  N + ID        N+++             C   GG + G+ C  + + D    S LL +GTF L+  LK MRN+ +FP+ VR L+SDFAVMIAI+SMT +D  +G +TPKLNVP+ F PT  ++ RGW IP    N WWT  +A+ PALLA ILIFMDQQIT VIVNRKENKLKKG GYHLDLLV+++ IL+   LG+P +VAATVLSINH+ SLK ESE  APGE   F+G REQRVTG + FL+IGLSV  T +L RIPM VLYGVFL+MG+++L G+QL  R  L FMP KYQPD I++R+VP+R++HLFT  QI  L LLWVIK+I   SI FPIM++ +  +RK +E  FT  +LK+LDD MP+ H +  +D           + E D E   +   +K TE +L    ++  VI+            IN+++E+  + +WK ++
Sbjct:   68 PGTRVMFLLKEKEN--TPALFTEMGELNNE-----EWRETARWVKFEEDVEQGGNRWSKPHVATLSLHSLFQLRSCIMNGHFMNDLAETDIPSIFNAVIENLEKSGDLPSENREELREILLRKHVHQYEQPPFWAFSRWFDDLVTSSSPSTSRTSSFSSHSLSSSQQVFHECLSNILLTISIRKAKKNGAGGEKGGFLSTVRSISDIGKSFSHGKNLSKIE---EKPEGPVTSQTAGAPSGSSNQLTLPTVESVPKD-ISSEE-------SSKGNLHFLKKLPAGVEASNVLIGEVDFLTRHICCFIRLKNANQLGDLTEVPVPTRFIFLLLGPTGHGQQYREIGRAIATLMADEIFHDVAYGARDVDDLLDGIDEFLDQVTVLPPGEWDPNIRIEPPSKLPSQEKRKQI--GQELLVEPSSHKH-----------------VKKV--VEEEEIHSHGDDPALKRTGKLFGGLILDIKRKAPHFVSDFTDAFNLQCLASICFMYFGLLAPIVTFGGLLEEATHQRMAAMENLFGGALCGVIYHFFAGQPLTIVGSTGPVLVFETIVFDFCHRFGIVYLSFRFWVHVWTAVIIFLMVVTDASALVSFITRFTEESFATLIAVIFIYEAIMKLVKIKGQLDM-INYSRDFVEGGFCSCVPPIGKPSVSPDH--------ARLVIKSTGLPIAFNDTFIDYTA----ANLTD-------------CRTIGGSFDGTTC--FPLYDKLLMSILLTVGTFFLATTLKKMRNSCYFPSSVRQLLSDFAVMIAIASMTFVDIFVGVNTPKLNVPSTFRPT--WEGRGWFIPPFDANEWWTAPLAILPALLACILIFMDQQITTVIVNRKENKLKKGCGYHLDLLVLSVSILMVGFLGLPIYVAATVLSINHINSLKVESECKAPGEVAQFVGVREQRVTGIVTFLIIGLSVLATNILGRIPMPVLYGVFLYMGISALGGIQLFDRTLLLFMPMKYQPDTIYIRHVPIRKIHLFTAFQIGCLALLWVIKSIKSTSILFPIMLVVMVAIRKMMEKAFTTTDLKYLDDPMPDFHLRKKEDAKRRQSEGEAVEIEFDNENQATIHAVK-TEAHLHIPMASGNVIKIPLAAIQEPSHSINLTKEVNNSGMWKHIT 1140          
BLAST of slc4a-1 vs. Ensembl Celegans
Match: abts-3 (Anion/Bicarbonate TranSporter family [Source:UniProtKB/TrEMBL;Acc:A0A3B1E4W4])

HSP 1 Score: 175.252 bits (443), Expect = 2.613e-44
Identity = 160/543 (29.47%), Postives = 249/543 (45.86%), Query Frame = 2
Query: 1583 FGGLIEDVKRKAPFYLSDFKDAIH-----VQCFASFFFLYFACLTPIITFGGLLVQATGGYLGAIESILSGTIVGVVYSLFSGQPLTIMGSTGPVLVFESIVYNICERMRWDYLPFRLWIGVWIAAYLFLMVAFDLSALVRYITRFTEESFAALIALIFMVEAFKKLF--LIVDYYPIDTRWNIDMIKNRTCECFPRNATAMDAFFQKNNKPSNVYMPPMLYPVPLNSSVIDIVNNIDWQNISNYHFTWDYKKYRLICTKWGGIW-TGSGCGNYFIPDVFFFSCLLFIGTFVLSYGLKMMRNAQFFPNWVRSLISDFAVMIAISSMTLLDWSLGFHTPKLNVPAKFEPTLGYKMRGWVIPALGKNPWWTIIIAMGPALLAVILIFMDQQITAVIVNRKENKLKKGSGYHXXXXXXXXXXXXXXXXGIPWFVAATVLSINHVMSLKKESENTAPGE-RPVFLGCREQRVTGTIIFLVIGLSV-FLTPL-LKRIPMAVLYGVFLFMGVASLKGVQLMQRISLFFMPAKYQPDYIFLRYVPLRRVH 3178
            F GL+E+ KR+   Y SD+ D I       + F++  FLYFACL P I FG L    T G +   + I++  I G+ +SLF GQP+ I+ +T P+ ++  +++ I + + +D+L     +G++   +L L  A +L +L+++ TR  EE F+  IA+ F VE+ + +      +Y   DT   I M   R         TA++AF   +N  S                   IV NI                     T    I  TGS C      D      LL  GT  L   L   R   +     R  ++D+A+  ++  M+           K     +FE  L        +P  G        + +        L F+DQ IT+ IVN  +NKLKKG+ ++LDL VVA+L +  S+ G+PW   A   S  H+ +L    E  + G    V +  RE R+   I  ++I +S+ FL P  L+ IP +VL+G+FL+M + SL G ++ +R+ L     +  P   ++R VP R+VH
Sbjct:  418 FRGLVEEFKRRLAIYPSDYLDGIRGHKTVQKLFSTVVFLYFACLLPAIAFGVLNDDNTKGAINVRKVIIAQAIGGIFFSLFGGQPMIILLTTVPLAIYIKVIFKISQELGYDFLAMYACVGLFCQMFLILYSATELCSLMKFATRSAEEMFSLFIAIAFTVESIRAIHNSFKKNYNDCDTSA-ISMKAAR---------TALNAFKNGSNADS-------------------IVGNI---------------------TSSMSIGDTGSLCRR----DTSILYMLLMFGTLWLGLFLYNFRKTPYLTRSRREWLADYALPASVLIMSFTGSYAFSDIEKDRFNLRFEFPLIQMADVTSLPPSG------YFVCLLLGFSLSFLFFIDQNITSAIVNNNQNKLKKGTSHNLDLFVVALLNMFLSVFGLPWMHGALPHSPLHLRALADVEERVSQGHVHEVIMNVRETRLASLIAHVMILVSMFFLIPYPLQLIPTSVLHGLFLYMALTSLSGNEMFERLLLLITEQQAYPPTHYIRKVPQRKVH 900          
BLAST of slc4a-1 vs. Ensembl Celegans
Match: abts-3 (Anion/Bicarbonate TranSporter family [Source:UniProtKB/TrEMBL;Acc:A0A3B1E4W4])

HSP 1 Score: 175.252 bits (443), Expect = 4.279e-44
Identity = 159/543 (29.28%), Postives = 250/543 (46.04%), Query Frame = 2
Query: 1583 FGGLIEDVKRKAPFYLSDFKDAIH-----VQCFASFFFLYFACLTPIITFGGLLVQATGGYLGAIESILSGTIVGVVYSLFSGQPLTIMGSTGPVLVFESIVYNICERMRWDYLPFRLWIGVWIAAYLFLMVAFDLSALVRYITRFTEESFAALIALIFMVEAFKKLF--LIVDYYPIDTRWNIDMIKNRTCECFPRNATAMDAFFQKNNKPSNVYMPPMLYPVPLNSSVIDIVNNI-DWQNISNYHFTWDYKKYRLICTKWGGIWTGSGCGNYFIPDVFFFSCLLFIGTFVLSYGLKMMRNAQFFPNWVRSLISDFAVMIAISSMTLLDWSLGFHTPKLNVPAKFEPTLGYKMRGWVIPALGKNPWWTIIIAMGPALLAVILIFMDQQITAVIVNRKENKLKKGSGYHXXXXXXXXXXXXXXXXGIPWFVAATVLSINHVMSLKKESENTAPGE-RPVFLGCREQRVTGTIIFLVIGLSV-FLTPL-LKRIPMAVLYGVFLFMGVASLKGVQLMQRISLFFMPAKYQPDYIFLRYVPLRRVH 3178
            F GL+E+ KR+   Y SD+ D I       + F++  FLYFACL P I FG L    T G +   + I++  I G+ +SLF GQP+ I+ +T P+ ++  +++ I + + +D+L     +G++   +L L  A +L +L+++ TR  EE F+  IA+ F VE+ + +      +Y   DT   I M   R         TA++AF   +N  S                   IV NI    +I +                     TGS C      D      LL  GT  L   L   R   +     R  ++D+A+  ++  M+           K     +FE  L        +P  G        + +        L F+DQ IT+ IVN  +NKLKKG+ ++LDL VVA+L +  S+ G+PW   A   S  H+ +L    E  + G    V +  RE R+   I  ++I +S+ FL P  L+ IP +VL+G+FL+M + SL G ++ +R+ L     +  P   ++R VP R+VH
Sbjct:  502 FRGLVEEFKRRLAIYPSDYLDGIRGHKTVQKLFSTVVFLYFACLLPAIAFGVLNDDNTKGAINVRKVIIAQAIGGIFFSLFGGQPMIILLTTVPLAIYIKVIFKISQELGYDFLAMYACVGLFCQMFLILYSATELCSLMKFATRSAEEMFSLFIAIAFTVESIRAIHNSFKKNYNDCDTS-AISMKAAR---------TALNAFKNGSNADS-------------------IVGNITSSMSIGD---------------------TGSLCRR----DTSILYMLLMFGTLWLGLFLYNFRKTPYLTRSRREWLADYALPASVLIMSFTGSYAFSDIEKDRFNLRFEFPLIQMADVTSLPPSG------YFVCLLLGFSLSFLFFIDQNITSAIVNNNQNKLKKGTSHNLDLFVVALLNMFLSVFGLPWMHGALPHSPLHLRALADVEERVSQGHVHEVIMNVRETRLASLIAHVMILVSMFFLIPYPLQLIPTSVLHGLFLYMALTSLSGNEMFERLLLLITEQQAYPPTHYIRKVPQRKVH 984          
BLAST of slc4a-1 vs. Ensembl Fly
Match: Ndae1 (gene:FBgn0259111 transcript:FBtr0331658)

HSP 1 Score: 904.049 bits (2335), Expect = 0.000e+0
Identity = 537/1161 (46.25%), Postives = 707/1161 (60.90%), Query Frame = 2
Query:  173 SEDEIEDHRSQRALYIGVHMPPDXXXXXXXXX----------------XXXXXXXXXXXXDKKDYLTEIAEDDTEKATDPSQHVMFLLGEDEDEETH---NLFCEMDELRLDDEGEPEWKETARWIKFEEDVEEGGERWSKPHVASLSLYSLFEVRNCITSAVNMFNVEANNFETIIEIILNKIVSEKKISPDQREKVKEMLQRKHVHLHERRHKSNAKGSQLPLIRSLADIGKKYSSKEVDKVQLQRRNSDYPTKFTRFDANXXXXXXXXXXXXXYVDKNRIDVDQCGSDNLASQ--KFDLHFFKKIPLGAETSNIMVGETDFLNQMVVVFIRLKEAVILGELTEVPVPTRFVFVMLGPQGSAVKNHEIGRSMATLMSDDVFHDVAYKARNLDDLLAGIDEFLSNCTVLPPAEWDPSIRIEPPKSGP---IARKVPSMPNGAQALLTASGDGRXXXXXXXXXXXXXXASVVNKLQPVEEESHADPTLRRTGRLFGGLIEDVKRKAPFYLSDFKDAIHVQCFASFFFLYFACLTPIITFGGLLVQATGGYLGAIESILSGTIVGVVYSLFSGQPLTIMGSTGPVLVFESIVYNICERMRWDYLPFRLWIGVWIAAYLFLMVAFDLSALVRYITRFTEESFAALIALIFMVEAFKKLFLIVDYYPIDTRWNIDMIKNRTCECFPRNATAMDAFFQKNNKPSNVYMPPMLYPVPLNSSVIDIVNNIDWQNISNYHFTWDYKKYRLICTKWGGIWTGSGCGNYFIPDVFFFSCLLFIGTFVLSYGLKMMRNAQFFPNWVRSLISDFAVMIAISSMTLLDWSLGFHTPKLNVPAKFEPTLGYKMRGWVIPA-LGKNPWWTIIIAMGPALLAVILIFMDQQITAVIVNRKENKLKKGSGYHXXXXXXXXXXXXXXXXGIPWFVAATVLSINHVMSLKKESENTAPGERPVFLGCREQRVTGTIIFLVIGLSVFLTPLLKRIPMAVLYGVFLFMGVASLKGVQLMQRISLFFMPAKYQPDYIFLRYVPLRRVHXXXXXXXXXXXXXXXXXXXNVMSICFPIMVLALCFVRKGLEYLFTYNELKWLDDIMPN----------HKKPPQDDNENDIEKCGST---ELIKMTETNLEFNSSTNKVIRSNDSGINISEE-MGKTAIWKQLS 3538
            +E++ E HR+   +Y+GVH+P  R H   R++                         G    KD ++E  ++     T P+Q V F+LGED D+ TH    LF EM  L + +  E EWKETARWIKFEEDVEEGG RWSKPHVA+LSL+SLFE+R  + +   M ++EA N E + +++ + +VS   + P  ++KVK+ L R+H H HE      AK ++LP+IRSLAD+    SSK+        R +   +  T                 +    N+          L+ Q  K + HF +KIP GAE SNI+VGE DFL + +  FIRL +AV+LG+LTEVPVPTRFVF++LGP GS    HEIGR+MATLMSD++FH+VAY+AR  D LL+G+DEFL   TVLPP EWDP+IRIEPP + P   + ++ P +P                                            +  L RTGRLFGGLI D+KRKAP+Y+SD+KDA+ +QC AS+ FLYFACL+PIITFGGLL +ATG ++ A+ES++SG + G+ Y  FSGQPLTI+GSTGPVLVFESI+Y  C +M WDY+ FR WIG+W+A    ++ A D SALV YITRFTEE+FA LIA IF+ +A + + +I   +P++            C C P                          P+  N+SVID              + WD       C  + G   G  CG     +VF  S +L  GTF++S  LK  +NA FFP+ VR  ISDF+V+IAI +M+  D+SLG  T KL VP + +PTL    RGW+IP  + KNPWW+ IIA+ PALL  ILIFMDQQITAVIVNRKENKLKKG GYHLDL +++ILI + S++G+PWFVAATVLSINHV SLK ESE +APGE+P FLG REQRVT  +IFL IG+SV LTPLL  IPM VL+GVFL+MGVASLKG+Q   RI + FMPAKYQPDY+FLR VP++RVHLFT+IQ+  L++LW+IK+ +  SI FP+M++ +  +RK L+ +FT  ELK LDDIMP           HK   +D++       G+       K   T +    S NK   +    +NI +E + +TA+W+Q++
Sbjct:   26 TENDFEGHRAH-TVYVGVHVPGGRRHSQRRRKHHHSGPGGGGGGGGGGGSIGGSGSVGGGAGKDNVSEKQQEVERPVTPPAQRVQFILGEDVDDGTHVSHPLFSEMGML-VKEGDEIEWKETARWIKFEEDVEEGGNRWSKPHVATLSLHSLFELRRLLVNGSVMLDMEAQNLEVMADLVCDHMVSAGTLPPGVKDKVKDALLRRHRHQHEY-----AKKTRLPIIRSLADMRNHSSSKKKKSNSKHSRPAQNLSSITE--------------DMVKSPSNQSMARPGSGTELSEQQHKGNTHFMRKIPPGAEASNILVGEVDFLERTLSCFIRLSQAVVLGDLTEVPVPTRFVFILLGPPGSQSNFHEIGRAMATLMSDEIFHEVAYRARKRDHLLSGVDEFLDAVTVLPPGEWDPTIRIEPPAAIPSQEVRKRPPELPKEEVDEEEEE-----------------------------ARLREENGLSRTGRLFGGLINDIKRKAPWYISDYKDALSMQCVASWIFLYFACLSPIITFGGLLAEATGKHMAAMESLVSGFVCGMGYGFFSGQPLTILGSTGPVLVFESIIYEFCLKMGWDYMTFRFWIGMWVAGICIVLTAIDASALVCYITRFTEENFATLIAFIFIYKAIENVMVIGKNFPVNQ-------GIYDCVCTP--------------------------PIGSNASVIDYAK-----------YNWDS------CESYNGTLVGGDCGTPPTENVFLMSVVLCAGTFLISTVLKEFKNALFFPSIVRQYISDFSVLIAIFAMSFFDYSLGVPTQKLEVPNELKPTL--STRGWLIPPFVEKNPWWSAIIAVFPALLGTILIFMDQQITAVIVNRKENKLKKGCGYHLDLFILSILIAICSMMGLPWFVAATVLSINHVNSLKLESECSAPGEKPQFLGVREQRVTHILIFLTIGVSVLLTPLLGNIPMPVLFGVFLYMGVASLKGLQFFDRILIMFMPAKYQPDYMFLRQVPIKRVHLFTMIQLACLIILWLIKSFSQTSILFPLMLVVMIGIRKALDLVFTRRELKILDDIMPEMTKRAAADDLHKLDAEDNHHQHPPGSGAGANYNADKSGPTTIHIPLSGNKT-GTKGPTVNIPQEAVNRTAVWQQIN 1083          
BLAST of slc4a-1 vs. Ensembl Fly
Match: Ndae1 (gene:FBgn0259111 transcript:FBtr0299539)

HSP 1 Score: 903.664 bits (2334), Expect = 0.000e+0
Identity = 537/1161 (46.25%), Postives = 707/1161 (60.90%), Query Frame = 2
Query:  173 SEDEIEDHRSQRALYIGVHMPPDXXXXXXXXX----------------XXXXXXXXXXXXDKKDYLTEIAEDDTEKATDPSQHVMFLLGEDEDEETH---NLFCEMDELRLDDEGEPEWKETARWIKFEEDVEEGGERWSKPHVASLSLYSLFEVRNCITSAVNMFNVEANNFETIIEIILNKIVSEKKISPDQREKVKEMLQRKHVHLHERRHKSNAKGSQLPLIRSLADIGKKYSSKEVDKVQLQRRNSDYPTKFTRFDANXXXXXXXXXXXXXYVDKNRIDVDQCGSDNLASQ--KFDLHFFKKIPLGAETSNIMVGETDFLNQMVVVFIRLKEAVILGELTEVPVPTRFVFVMLGPQGSAVKNHEIGRSMATLMSDDVFHDVAYKARNLDDLLAGIDEFLSNCTVLPPAEWDPSIRIEPPKSGP---IARKVPSMPNGAQALLTASGDGRXXXXXXXXXXXXXXASVVNKLQPVEEESHADPTLRRTGRLFGGLIEDVKRKAPFYLSDFKDAIHVQCFASFFFLYFACLTPIITFGGLLVQATGGYLGAIESILSGTIVGVVYSLFSGQPLTIMGSTGPVLVFESIVYNICERMRWDYLPFRLWIGVWIAAYLFLMVAFDLSALVRYITRFTEESFAALIALIFMVEAFKKLFLIVDYYPIDTRWNIDMIKNRTCECFPRNATAMDAFFQKNNKPSNVYMPPMLYPVPLNSSVIDIVNNIDWQNISNYHFTWDYKKYRLICTKWGGIWTGSGCGNYFIPDVFFFSCLLFIGTFVLSYGLKMMRNAQFFPNWVRSLISDFAVMIAISSMTLLDWSLGFHTPKLNVPAKFEPTLGYKMRGWVIPA-LGKNPWWTIIIAMGPALLAVILIFMDQQITAVIVNRKENKLKKGSGYHXXXXXXXXXXXXXXXXGIPWFVAATVLSINHVMSLKKESENTAPGERPVFLGCREQRVTGTIIFLVIGLSVFLTPLLKRIPMAVLYGVFLFMGVASLKGVQLMQRISLFFMPAKYQPDYIFLRYVPLRRVHXXXXXXXXXXXXXXXXXXXNVMSICFPIMVLALCFVRKGLEYLFTYNELKWLDDIMPN----------HKKPPQDDNENDIEKCGST---ELIKMTETNLEFNSSTNKVIRSNDSGINISEE-MGKTAIWKQLS 3538
            +E++ E HR+   +Y+GVH+P  R H   R++                         G    KD ++E  ++     T P+Q V F+LGED D+ TH    LF EM  L + +  E EWKETARWIKFEEDVEEGG RWSKPHVA+LSL+SLFE+R  + +   M ++EA N E + +++ + +VS   + P  ++KVK+ L R+H H HE      AK ++LP+IRSLAD+    SSK+        R +   +  T                 +    N+          L+ Q  K + HF +KIP GAE SNI+VGE DFL + +  FIRL +AV+LG+LTEVPVPTRFVF++LGP GS    HEIGR+MATLMSD++FH+VAY+AR  D LL+G+DEFL   TVLPP EWDP+IRIEPP + P   + ++ P +P                                            +  L RTGRLFGGLI D+KRKAP+Y+SD+KDA+ +QC AS+ FLYFACL+PIITFGGLL +ATG ++ A+ES++SG + G+ Y  FSGQPLTI+GSTGPVLVFESI+Y  C +M WDY+ FR WIG+W+A    ++ A D SALV YITRFTEE+FA LIA IF+ +A + + +I   +P++            C C P                          P+  N+SVID              + WD       C  + G   G  CG     +VF  S +L  GTF++S  LK  +NA FFP+ VR  ISDF+V+IAI +M+  D+SLG  T KL VP + +PTL    RGW+IP  + KNPWW+ IIA+ PALL  ILIFMDQQITAVIVNRKENKLKKG GYHLDL +++ILI + S++G+PWFVAATVLSINHV SLK ESE +APGE+P FLG REQRVT  +IFL IG+SV LTPLL  IPM VL+GVFL+MGVASLKG+Q   RI + FMPAKYQPDY+FLR VP++RVHLFT+IQ+  L++LW+IK+ +  SI FP+M++ +  +RK L+ +FT  ELK LDDIMP           HK   +D++       G+       K   T +    S NK   +    +NI +E + +TA+W+Q++
Sbjct:   39 TENDFEGHRAH-TVYVGVHVPGGRRHSQRRRKHHHSGPGGGGGGGGGGGSIGGSGSVGGGAGKDNVSEKQQEVERPVTPPAQRVQFILGEDVDDGTHVSHPLFSEMGML-VKEGDEIEWKETARWIKFEEDVEEGGNRWSKPHVATLSLHSLFELRRLLVNGSVMLDMEAQNLEVMADLVCDHMVSAGTLPPGVKDKVKDALLRRHRHQHEY-----AKKTRLPIIRSLADMRNHSSSKKKKSNSKHSRPAQNLSSITE--------------DMVKSPSNQSMARPGSGTELSEQQHKGNTHFMRKIPPGAEASNILVGEVDFLERTLSCFIRLSQAVVLGDLTEVPVPTRFVFILLGPPGSQSNFHEIGRAMATLMSDEIFHEVAYRARKRDHLLSGVDEFLDAVTVLPPGEWDPTIRIEPPAAIPSQEVRKRPPELPKEEVDEEEEE-----------------------------ARLREENGLSRTGRLFGGLINDIKRKAPWYISDYKDALSMQCVASWIFLYFACLSPIITFGGLLAEATGKHMAAMESLVSGFVCGMGYGFFSGQPLTILGSTGPVLVFESIIYEFCLKMGWDYMTFRFWIGMWVAGICIVLTAIDASALVCYITRFTEENFATLIAFIFIYKAIENVMVIGKNFPVNQGI-------YDCVCTP--------------------------PIGSNASVIDYAK-----------YNWDS------CESYNGTLVGGDCGTPPTENVFLMSVVLCAGTFLISTVLKEFKNALFFPSIVRQYISDFSVLIAIFAMSFFDYSLGVPTQKLEVPNELKPTL--STRGWLIPPFVEKNPWWSAIIAVFPALLGTILIFMDQQITAVIVNRKENKLKKGCGYHLDLFILSILIAICSMMGLPWFVAATVLSINHVNSLKLESECSAPGEKPQFLGVREQRVTHILIFLTIGVSVLLTPLLGNIPMPVLFGVFLYMGVASLKGLQFFDRILIMFMPAKYQPDYMFLRQVPIKRVHLFTMIQLACLIILWLIKSFSQTSILFPLMLVVMIGIRKALDLVFTRRELKILDDIMPEMTKRAAADDLHKLDAEDNHHQHPPGSGAGANYNADKSGPTTIHIPLSGNKT-GTKGPTVNIPQEAVNRTAVWQQIN 1096          
BLAST of slc4a-1 vs. Ensembl Fly
Match: Ndae1 (gene:FBgn0259111 transcript:FBtr0331663)

HSP 1 Score: 902.123 bits (2330), Expect = 0.000e+0
Identity = 526/1112 (47.30%), Postives = 685/1112 (61.60%), Query Frame = 2
Query:  173 SEDEIEDHRSQRALYIGVHMPPDXXXXXXXXX----------------XXXXXXXXXXXXDKKDYLTEIAEDDTEKATDPSQHVMFLLGEDEDEETH---NLFCEMDELRLDDEGEPEWKETARWIKFEEDVEEGGERWSKPHVASLSLYSLFEVRNCITSAVNMFNVEANNFETIIEIILNKIVSEKKISPDQREKVKEMLQRKHVHLHERRHKSNAKGSQLPLIRSLADIGKKYSSKEVDKV----QLQRRNSDYPTKFTRFDANXXXXXXXXXXXXXYVDKNRIDVDQCGSDNLA-----------SQKFDLHFFKKIPLGAETSNIMVGETDFLNQMVVVFIRLKEAVILGELTEVPVPTRFVFVMLGPQGSAVKNHEIGRSMATLMSDDVFHDVAYKARNLDDLLAGIDEFLSNCTVLPPAEWDPSIRIEPPKSGP---IARKVPSMPNGAQALLTASGDGRXXXXXXXXXXXXXXASVVNKLQPVEEESHADPTLRRTGRLFGGLIEDVKRKAPFYLSDFKDAIHVQCFASFFFLYFACLTPIITFGGLLVQATGGYLGAIESILSGTIVGVVYSLFSGQPLTIMGSTGPVLVFESIVYNICERMRWDYLPFRLWIGVWIAAYLFLMVAFDLSALVRYITRFTEESFAALIALIFMVEAFKKLFLIVDYYPIDTRWNIDMIKNRTCECFPRNATAMDAFFQKNNKPSNVYMPPMLYPVPLNSSVIDIVNNIDWQNISNYHFTWDYKKYRLICTKWGGIWTGSGCGNYFIPDVFFFSCLLFIGTFVLSYGLKMMRNAQFFPNWVRSLISDFAVMIAISSMTLLDWSLGFHTPKLNVPAKFEPTLGYKMRGWVIPA-LGKNPWWTIIIAMGPALLAVILIFMDQQITAVIVNRKENKLKKGSGYHXXXXXXXXXXXXXXXXGIPWFVAATVLSINHVMSLKKESENTAPGERPVFLGCREQRVTGTIIFLVIGLSVFLTPLLKRIPMAVLYGVFLFMGVASLKGVQLMQRISLFFMPAKYQPDYIFLRYVPLRRVHXXXXXXXXXXXXXXXXXXXNVMSICFPIMVLALCFVRKGLEYLFTYNELKWLDDIMPNHKKPPQDDNENDIE 3394
            +E++ E HR+   +Y+GVH+P  R H   R++                         G    KD ++E  ++     T P+Q V F+LGED D+ TH    LF EM  L + +  E EWKETARWIKFEEDVEEGG RWSKPHVA+LSL+SLFE+R  + +   M ++EA N E + +++ + +VS   + P  ++KVK+ L R+H H HE      AK ++LP+IRSLAD+    SSK + K      L    +      TR D      S                V    + ++A             K + HF +KIP GAE SNI+VGE DFL + +  FIRL +AV+LG+LTEVPVPTRFVF++LGP GS    HEIGR+MATLMSD++FH+VAY+AR  D LL+G+DEFL   TVLPP EWDP+IRIEPP + P   + ++ P +P                                            +  L RTGRLFGGLI D+KRKAP+Y+SD+KDA+ +QC AS+ FLYFACL+PIITFGGLL +ATG ++ A+ES++SG + G+ Y  FSGQPLTI+GSTGPVLVFESI+Y  C +M WDY+ FR WIG+W+A    ++ A D SALV YITRFTEE+FA LIA IF+ +A + + +I   +P++            C C P                          P+  N+SVID              + WD       C  + G   G  CG     +VF  S +L  GTF++S  LK  +NA FFP+ VR  ISDF+V+IAI +M+  D+SLG  T KL VP + +PTL    RGW+IP  + KNPWW+ IIA+ PALL  ILIFMDQQITAVIVNRKENKLKKG GYHLDL +++ILI + S++G+PWFVAATVLSINHV SLK ESE +APGE+P FLG REQRVT  +IFL IG+SV LTPLL  IPM VL+GVFL+MGVASLKG+Q   RI + FMPAKYQPDY+FLR VP++RVHLFT+IQ+  L++LW+IK+ +  SI FP+M++ +  +RK L+ +FT  ELK LDDIMP   K    D+ + ++
Sbjct:   39 TENDFEGHRAH-TVYVGVHVPGGRRHSQRRRKHHHSGPGGGGGGGGGGGSIGGSGSVGGGAGKDNVSEKQQEVERPVTPPAQRVQFILGEDVDDGTHVSHPLFSEMGML-VKEGDEIEWKETARWIKFEEDVEEGGNRWSKPHVATLSLHSLFELRRLLVNGSVMLDMEAQNLEVMADLVCDHMVSAGTLPPGVKDKVKDALLRRHRHQHEY-----AKKTRLPIIRSLADMRNHSSSKNLGKSTPLHSLHGSAAGLDLTGTRPDQTPLYVSSKDQRGCYLAVPTEDMVKSPSNQSMARPGSGTELSEQQHKGNTHFMRKIPPGAEASNILVGEVDFLERTLSCFIRLSQAVVLGDLTEVPVPTRFVFILLGPPGSQSNFHEIGRAMATLMSDEIFHEVAYRARKRDHLLSGVDEFLDAVTVLPPGEWDPTIRIEPPAAIPSQEVRKRPPELPKEEVDEEEEE-----------------------------ARLREENGLSRTGRLFGGLINDIKRKAPWYISDYKDALSMQCVASWIFLYFACLSPIITFGGLLAEATGKHMAAMESLVSGFVCGMGYGFFSGQPLTILGSTGPVLVFESIIYEFCLKMGWDYMTFRFWIGMWVAGICIVLTAIDASALVCYITRFTEENFATLIAFIFIYKAIENVMVIGKNFPVNQ-------GIYDCVCTP--------------------------PIGSNASVIDYAK-----------YNWDS------CESYNGTLVGGDCGTPPTENVFLMSVVLCAGTFLISTVLKEFKNALFFPSIVRQYISDFSVLIAIFAMSFFDYSLGVPTQKLEVPNELKPTL--STRGWLIPPFVEKNPWWSAIIAVFPALLGTILIFMDQQITAVIVNRKENKLKKGCGYHLDLFILSILIAICSMMGLPWFVAATVLSINHVNSLKLESECSAPGEKPQFLGVREQRVTHILIFLTIGVSVLLTPLLGNIPMPVLFGVFLYMGVASLKGLQFFDRILIMFMPAKYQPDYMFLRQVPIKRVHLFTMIQLACLIILWLIKSFSQTSILFPLMLVVMIGIRKALDLVFTRRELKILDDIMPEMTKRAAADDLHKLD 1062          
BLAST of slc4a-1 vs. Ensembl Fly
Match: Ndae1 (gene:FBgn0259111 transcript:FBtr0331660)

HSP 1 Score: 899.812 bits (2324), Expect = 0.000e+0
Identity = 510/1036 (49.23%), Postives = 659/1036 (63.61%), Query Frame = 2
Query:  311 KDYLTEIAEDDTEKATDPSQHVMFLLGEDEDEETH---NLFCEMDELRLDDEGEPEWKETARWIKFEEDVEEGGERWSKPHVASLSLYSLFEVRNCITSAVNMFNVEANNFETIIEIILNKIVSEKKISPDQREKVKEMLQRKHVHLHERRHKSNAKGSQLPLIRSLADIGKKYSSKEVDKVQLQRRNS-DYPTKFTRFDANXXXXXXXXXXXXXYVDKNRIDVDQCGSDNLASQKFDLHFFKKIPLGAETSNIMVGETDFLNQMVVVFIRLKEAVILGELTEVPVPTRFVFVMLGPQGSAVKNHEIGRSMATLMSDDVFHDVAYKARNLDDLLAGIDEFLSNCTVLPPAEWDPSIRIEPPKSGP---IARKVPSMPNGAQALLTASGDGRXXXXXXXXXXXXXXASVVNKLQPVEEESHADPTLRRTGRLFGGLIEDVKRKAPFYLSDFKDAIHVQCFASFFFLYFACLTPIITFGGLLVQATGGYLGAIESILSGTIVGVVYSLFSGQPLTIMGSTGPVLVFESIVYNICERMRWDYLPFRLWIGVWIAAYLFLMVAFDLSALVRYITRFTEESFAALIALIFMVEAFKKLFLIVDYYPIDTRWNIDMIKNRTCECFPRNATAMDAFFQKNNKPSNVYMPPMLYPVPLNSSVIDIVNNIDWQNISNYHFTWDYKKYRLICTKWGGIWTGSGCGNYFIPDVFFFSCLLFIGTFVLSYGLKMMRNAQFFPNWVRSLISDFAVMIAISSMTLLDWSLGFHTPKLNVPAKFEPTLGYKMRGWVIPA-LGKNPWWTIIIAMGPALLAVILIFMDQQITAVIVNRKENKLKKGSGYHXXXXXXXXXXXXXXXXGIPWFVAATVLSINHVMSLKKESENTAPGERPVFLGCREQRVTGTIIFLVIGLSVFLTPLLKRIPMAVLYGVFLFMGVASLKGVQLMQRISLFFMPAKYQPDYIFLRYVPLRRVHXXXXXXXXXXXXXXXXXXXNVMSICFPIMVLALCFVRKGLEYLFTYNELKWLDDIMPNHKKPPQDDNENDIE 3394
            +D+  +  E+D E  T P+Q V F+LGED D+ TH    LF EM  L + +  E EWKETARWIKFEEDVEEGG RWSKPHVA+LSL+SLFE+R  + +   M ++EA N E + +++ + +VS   + P  ++KVK+ L R+H H HE      AK ++LP+IRSLAD+ + +SS + D V+     S   P   T                                      K + HF +KIP GAE SNI+VGE DFL + +  FIRL +AV+LG+LTEVPVPTRFVF++LGP GS    HEIGR+MATLMSD++FH+VAY+AR  D LL+G+DEFL   TVLPP EWDP+IRIEPP + P   + ++ P +P                                            +  L RTGRLFGGLI D+KRKAP+Y+SD+KDA+ +QC AS+ FLYFACL+PIITFGGLL +ATG ++ A+ES++SG + G+ Y  FSGQPLTI+GSTGPVLVFESI+Y  C +M WDY+ FR WIG+W+A    ++ A D SALV YITRFTEE+FA LIA IF+ +A + + +I   +P++            C C P                          P+  N+SVID              + WD       C  + G   G  CG     +VF  S +L  GTF++S  LK  +NA FFP+ VR  ISDF+V+IAI +M+  D+SLG  T KL VP + +PTL    RGW+IP  + KNPWW+ IIA+ PALL  ILIFMDQQITAVIVNRKENKLKKG GYHLDL +++ILI + S++G+PWFVAATVLSINHV SLK ESE +APGE+P FLG REQRVT  +IFL IG+SV LTPLL  IPM VL+GVFL+MGVASLKG+Q   RI + FMPAKYQPDY+FLR VP++RVHLFT+IQ+  L++LW+IK+ +  SI FP+M++ +  +RK L+ +FT  ELK LDDIMP   K    D+ + ++
Sbjct:   48 EDFTQQFTENDFE-VTPPAQRVQFILGEDVDDGTHVSHPLFSEMGML-VKEGDEIEWKETARWIKFEEDVEEGGNRWSKPHVATLSLHSLFELRRLLVNGSVMLDMEAQNLEVMADLVCDHMVSAGTLPPGVKDKVKDALLRRHRHQHEY-----AKKTRLPIIRSLADM-RNHSSSKKDMVKSPSNQSMARPGSGTELSEQ-------------------------------QHKGNTHFMRKIPPGAEASNILVGEVDFLERTLSCFIRLSQAVVLGDLTEVPVPTRFVFILLGPPGSQSNFHEIGRAMATLMSDEIFHEVAYRARKRDHLLSGVDEFLDAVTVLPPGEWDPTIRIEPPAAIPSQEVRKRPPELPKEEVDEEEEE-----------------------------ARLREENGLSRTGRLFGGLINDIKRKAPWYISDYKDALSMQCVASWIFLYFACLSPIITFGGLLAEATGKHMAAMESLVSGFVCGMGYGFFSGQPLTILGSTGPVLVFESIIYEFCLKMGWDYMTFRFWIGMWVAGICIVLTAIDASALVCYITRFTEENFATLIAFIFIYKAIENVMVIGKNFPVNQ-------GIYDCVCTP--------------------------PIGSNASVIDYAK-----------YNWDS------CESYNGTLVGGDCGTPPTENVFLMSVVLCAGTFLISTVLKEFKNALFFPSIVRQYISDFSVLIAIFAMSFFDYSLGVPTQKLEVPNELKPTL--STRGWLIPPFVEKNPWWSAIIAVFPALLGTILIFMDQQITAVIVNRKENKLKKGCGYHLDLFILSILIAICSMMGLPWFVAATVLSINHVNSLKLESECSAPGEKPQFLGVREQRVTHILIFLTIGVSVLLTPLLGNIPMPVLFGVFLYMGVASLKGLQFFDRILIMFMPAKYQPDYMFLRQVPIKRVHLFTMIQLACLIILWLIKSFSQTSILFPLMLVVMIGIRKALDLVFTRRELKILDDIMPEMTKRAAADDLHKLD 963          
BLAST of slc4a-1 vs. Ensembl Fly
Match: Ndae1 (gene:FBgn0259111 transcript:FBtr0331662)

HSP 1 Score: 899.042 bits (2322), Expect = 0.000e+0
Identity = 513/1046 (49.04%), Postives = 664/1046 (63.48%), Query Frame = 2
Query:  311 KDYLTEIAEDDTEKATDPSQHVMFLLGEDEDEETH---NLFCEMDELRLDDEGEPEWKETARWIKFEEDVEEGGERWSKPHVASLSLYSLFEVRNCITSAVNMFNVEANNFETIIEIILNKIVSEKKISPDQREKVKEMLQRKHVHLHERRHKSNAKGSQLPLIRSLADIGKKYSSKEVDKVQLQR-------RNSDYPTKFTRFDANXXXXXXXXXXXXXYVDK--NRIDVDQCGSDNLASQ--KFDLHFFKKIPLGAETSNIMVGETDFLNQMVVVFIRLKEAVILGELTEVPVPTRFVFVMLGPQGSAVKNHEIGRSMATLMSDDVFHDVAYKARNLDDLLAGIDEFLSNCTVLPPAEWDPSIRIEPPKSGP---IARKVPSMPNGAQALLTASGDGRXXXXXXXXXXXXXXASVVNKLQPVEEESHADPTLRRTGRLFGGLIEDVKRKAPFYLSDFKDAIHVQCFASFFFLYFACLTPIITFGGLLVQATGGYLGAIESILSGTIVGVVYSLFSGQPLTIMGSTGPVLVFESIVYNICERMRWDYLPFRLWIGVWIAAYLFLMVAFDLSALVRYITRFTEESFAALIALIFMVEAFKKLFLIVDYYPIDTRWNIDMIKNRTCECFPRNATAMDAFFQKNNKPSNVYMPPMLYPVPLNSSVIDIVNNIDWQNISNYHFTWDYKKYRLICTKWGGIWTGSGCGNYFIPDVFFFSCLLFIGTFVLSYGLKMMRNAQFFPNWVRSLISDFAVMIAISSMTLLDWSLGFHTPKLNVPAKFEPTLGYKMRGWVIPA-LGKNPWWTIIIAMGPALLAVILIFMDQQITAVIVNRKENKLKKGSGYHXXXXXXXXXXXXXXXXGIPWFVAATVLSINHVMSLKKESENTAPGERPVFLGCREQRVTGTIIFLVIGLSVFLTPLLKRIPMAVLYGVFLFMGVASLKGVQLMQRISLFFMPAKYQPDYIFLRYVPLRRVHXXXXXXXXXXXXXXXXXXXNVMSICFPIMVLALCFVRKGLEYLFTYNELKWLDDIMPNHKKPPQDDNENDIE 3394
            +D+  +  E+D E  T P+Q V F+LGED D+ TH    LF EM  L + +  E EWKETARWIKFEEDVEEGG RWSKPHVA+LSL+SLFE+R  + +   M ++EA N E + +++ + +VS   + P  ++KVK+ L R+H H HE      AK ++LP+IRSLAD+    SSK      L              P    +  A +      ++     V    N+          L+ Q  K + HF +KIP GAE SNI+VGE DFL + +  FIRL +AV+LG+LTEVPVPTRFVF++LGP GS    HEIGR+MATLMSD++FH+VAY+AR  D LL+G+DEFL   TVLPP EWDP+IRIEPP + P   + ++ P +P                                            +  L RTGRLFGGLI D+KRKAP+Y+SD+KDA+ +QC AS+ FLYFACL+PIITFGGLL +ATG ++ A+ES++SG + G+ Y  FSGQPLTI+GSTGPVLVFESI+Y  C +M WDY+ FR WIG+W+A    ++ A D SALV YITRFTEE+FA LIA IF+ +A + + +I   +P++            C C P                          P+  N+SVID              + WD       C  + G   G  CG     +VF  S +L  GTF++S  LK  +NA FFP+ VR  ISDF+V+IAI +M+  D+SLG  T KL VP + +PTL    RGW+IP  + KNPWW+ IIA+ PALL  ILIFMDQQITAVIVNRKENKLKKG GYHLDL +++ILI + S++G+PWFVAATVLSINHV SLK ESE +APGE+P FLG REQRVT  +IFL IG+SV LTPLL  IPM VL+GVFL+MGVASLKG+Q   RI + FMPAKYQPDY+FLR VP++RVHLFT+IQ+  L++LW+IK+ +  SI FP+M++ +  +RK L+ +FT  ELK LDDIMP   K    D+ + ++
Sbjct:   32 EDFTQQFTENDFE-VTPPAQRVQFILGEDVDDGTHVSHPLFSEMGML-VKEGDEIEWKETARWIKFEEDVEEGGNRWSKPHVATLSLHSLFELRRLLVNGSVMLDMEAQNLEVMADLVCDHMVSAGTLPPGVKDKVKDALLRRHRHQHEY-----AKKTRLPIIRSLADMRNHSSSKTDTSTHLGAIGVTTWFHAGASPQHQAQNHAQNQGRPQSQAIPKDMVKSPSNQSMARPGSGTELSEQQHKGNTHFMRKIPPGAEASNILVGEVDFLERTLSCFIRLSQAVVLGDLTEVPVPTRFVFILLGPPGSQSNFHEIGRAMATLMSDEIFHEVAYRARKRDHLLSGVDEFLDAVTVLPPGEWDPTIRIEPPAAIPSQEVRKRPPELPKEEVDEEEEE-----------------------------ARLREENGLSRTGRLFGGLINDIKRKAPWYISDYKDALSMQCVASWIFLYFACLSPIITFGGLLAEATGKHMAAMESLVSGFVCGMGYGFFSGQPLTILGSTGPVLVFESIIYEFCLKMGWDYMTFRFWIGMWVAGICIVLTAIDASALVCYITRFTEENFATLIAFIFIYKAIENVMVIGKNFPVNQ-------GIYDCVCTP--------------------------PIGSNASVIDYAK-----------YNWDS------CESYNGTLVGGDCGTPPTENVFLMSVVLCAGTFLISTVLKEFKNALFFPSIVRQYISDFSVLIAIFAMSFFDYSLGVPTQKLEVPNELKPTL--STRGWLIPPFVEKNPWWSAIIAVFPALLGTILIFMDQQITAVIVNRKENKLKKGCGYHLDLFILSILIAICSMMGLPWFVAATVLSINHVNSLKLESECSAPGEKPQFLGVREQRVTHILIFLTIGVSVLLTPLLGNIPMPVLFGVFLYMGVASLKGLQFFDRILIMFMPAKYQPDYMFLRQVPIKRVHLFTMIQLACLIILWLIKSFSQTSILFPLMLVVMIGIRKALDLVFTRRELKILDDIMPEMTKRAAADDLHKLD 989          
BLAST of slc4a-1 vs. Ensembl Zebrafish
Match: slc4a8 (solute carrier family 4 member 8 [Source:ZFIN;Acc:ZDB-GENE-131119-88])

HSP 1 Score: 939.102 bits (2426), Expect = 0.000e+0
Identity = 542/1173 (46.21%), Postives = 742/1173 (63.26%), Query Frame = 2
Query:  122 GDEPILDRG--FQFTHYHPSEDEIEDHRSQRALYIGVHMPPDXXXXXXXXXXXXXXXXXXXXXDKKDYLTEIAEDDTEKAT-----DPSQHVMFLLGEDEDEE--THNLFCEMDELRLDDEGEPEWKETARWIKFEEDVEEGGERWSKPHVASLSLYSLFEVRNCITSAVNMFNVEANNFETIIEIILNKIVSEKKISPDQREKVKEMLQRKHVHLHERRHKSNAKGSQLPLIRSLADIGKKYSSKE-VDKVQLQRRNSDYPTKFTRFDANXXXXXXXXXXXXXYVDKNRIDVDQCGSDNLASQKFDLHFFKKIPLGAETSNIMVGETDFLNQMVVVFIRLKEAVILGELTEVPVPTRFVFVMLGPQGSAVKNHEIGRSMATLMSDDVFHDVAYKARNLDDLLAGIDEFLSNCTVLPPAEWDPSIRIEPPKSGPIA--RKVPSMPNGAQALLTASGDGRXXXXXXXXXXXXXXASVVNKLQPVEEESHAD---PTLRRTGRLFGGLIEDVKRKAPFYLSDFKDAIHVQCFASFFFLYFACLTPIITFGGLLVQATGGYLGAIESILSGTIVGVVYSLFSGQPLTIMGSTGPVLVFESIVYNICERMRWDYLPFRLWIGVWIAAYLFLMVAFDLSALVRYITRFTEESFAALIALIFMVEAFKKLFLIVDYYPIDTRWNIDMIKNRTCECF----PRNATAMDAFFQKNNKPSNVYMPPMLYPVPLNSSVIDIVNNIDWQNISNYHFTWDYKKYRLICTKWGGIWTGSGCGNY--FIPDVFFFSCLLFIGTFVLSYGLKMMRNAQFFPNWVRSLISDFAVMIAISSMTLLDWSLGFHTPKLNVPAKFEPTLGYKMRGWVIPALGKNPWWTIIIAMGPALLAVILIFMDQQITAVIVNRKENKLKKGSGYHXXXXXXXXXXXXXXXXGIPWFVAATVLSINHVMSLKKESENTAPGERPVFLGCREQRVTGTIIFLVIGLSVFLTPLLKRIPMAVLYGVFLFMGVASLKGVQLMQRISLFFMPAKYQPDYIFLRYVPLRRVHXXXXXXXXXXXXXXXXXXXNVMSICFPIMVLALCFVRKGLEYLFTYNELKWLDDIMPNHK----------KPPQDDNENDIEKCGSTELIKMTETNLE---FNSSTNKVIRSNDSGINISEEMGKTAIWKQLS 3538
            G+E ++D G      + H  ++E+E HR+   L++GV MP DR      +      + +    D+        +DD  ++T      PSQ V F+LG +EDEE   H LF E+DE+ + +  + EWKETARW+KFEEDVE+GGERWSKP+VA+LSL+SLFE+R+CI +   + +++A + E I +++L K  +  ++    R KV+E L ++H H ++++     + + LP++++L +  +++S    +DK  L   +   PT  T                    D       + G  +L+  K D HF KKIP GAE SN++VGE DFL + +V F+RL  AV+L  LTEVP+PTRF+F++LGP G A + HEIGRSMAT+M+D++FHDVAYKA++  DLLAGIDEFL   TVLPP EWDPSIRIEPPK  P    RK+P +PNG                                   VEEE HA+   P L+RTGRLFGGLI D+KRKAP+YLSDFKD + +QC ASF FLY AC++P+ITFGGLL +AT G + AIES+L  ++ GV YSLF+GQPLTI+GSTGPVLVFE I++  C+     YL  R  IG+W A    L+VA D S+LV YITRFTEE+FAALI LIF+ EA +KLF + + YPI+   ++D +    C C     P N T ++ + Q+N   S V                       W N++              C    G + G  CG++  + PDV F+S +LF GTF++S  LK  + +++FP  VRS+ISDFAV + I  M L+D+ +G  + KL VP+KF+PT     RGWV+  +G+NPWWT++ A+ PALL  ILIFMDQQITAVI+NRKE+KL KG GYHLDLL+V +++ V S+LG+PWFVAATVLSI+HV SLK ESE++APGE+P FLG +EQR+TG  IFL++G SVF+T LL+ IPM VLYGVFL+MGV+SLKG+QL  R+ LF MPAK+QPD+I+LR+VPLR+VHLFT+ Q+  LVLLWVIK     +I FP+MVLAL F+RK L++ F+  EL +LDD+MP ++             Q+  E  +++ G ++     +  +E    +S      R++ S INIS+EM KT +WK L+
Sbjct:   18 GEEAVVDHGGTSSVLNIHYEKEELEGHRT---LFVGVRMPMDRPSHRHHRPHSSRHRRRS---DRMRAGGSAQDDDNSESTPGAHDTPSQRVRFILGTEEDEEHVAHELFTELDEICVKEGKDAEWKETARWLKFEEDVEDGGERWSKPYVATLSLHSLFELRSCIINGTVLLDMKAGSIEEIADLVLEKQETPHELDDSVRMKVREALLKRHHHQNDKK-----RNNLLPMVKTLTEANRRHSETHFMDKTGLAT-SPQPPTTST--------------------DIKNGATSEIGQMDLS--KVDTHFMKKIPTGAEASNVLVGELDFLERSIVAFVRLSPAVLLTGLTEVPIPTRFLFILLGPDGKAQQYHEIGRSMATIMTDEIFHDVAYKAKDRTDLLAGIDEFLDQVTVLPPGEWDPSIRIEPPKCVPSQEKRKMPGVPNGTAVT-------------------------------VEEELHAEHHGPELQRTGRLFGGLILDLKRKAPYYLSDFKDGLTLQCVASFLFLYCACMSPVITFGGLLGEATEGQISAIESLLGASMTGVAYSLFAGQPLTILGSTGPVLVFEKILFKFCKDYDLSYLSLRTCIGLWTAFLCLLLVATDASSLVCYITRFTEEAFAALICLIFIYEALEKLFYLGELYPINRHSDLDKLTLAYCRCAEPDNPSNKT-LEVWNQRNITASAV----------------------PWTNLTVTE-----------CLDLQGQFIGPSCGHHGPYTPDVLFWSSILFFGTFLMSSFLKQFKASRYFPTRVRSMISDFAVFLTIVFMVLIDYIIGVPSQKLQVPSKFKPT--RDDRGWVMNPIGRNPWWTVLAALIPALLCTILIFMDQQITAVIINRKEHKLVKGCGYHLDLLMVGVMLAVCSMLGLPWFVAATVLSISHVNSLKLESESSAPGEQPRFLGIQEQRLTGLFIFLLMGCSVFMTGLLQFIPMPVLYGVFLYMGVSSLKGIQLFDRLKLFGMPAKHQPDFIYLRHVPLRKVHLFTLTQLTCLVLLWVIKHSPA-AIVFPMMVLALVFIRKLLDFCFSKRELSYLDDLMPENRKKKLDDDSKKAEEQESQEMLVDESGESDNKDTVQIPMESKPLHSPRTPDPRTDPSDINISDEMSKTTVWKSLN 1088          
BLAST of slc4a-1 vs. Ensembl Zebrafish
Match: slc4a10a (solute carrier family 4 member 10a [Source:ZFIN;Acc:ZDB-GENE-100215-3])

HSP 1 Score: 910.212 bits (2351), Expect = 0.000e+0
Identity = 535/1160 (46.12%), Postives = 736/1160 (63.45%), Query Frame = 2
Query:  125 DEPILDRGFQFTHYHPS--EDEIEDHRSQRALYIGVHMPPDXXXXXXXXXXXXXXXXXXXXXDKKDYLTEIAEDDTEKATDPSQHVMFLLGEDEDEE--THNLFCEMDELRLDDEGEPEWKETARWIKFEEDVEEGGERWSKPHVASLSLYSLFEVRNCITSAVNMFNVEANNFETIIEIILNKIVSEKKISPDQREKVKEMLQRKHVHLHERRHKSNAKGSQLPLIRSLADIGKKYSS-KEVDK------VQLQRRNSDYPTKFTRFDANXXXXXXXXXXXXXYVDKNRIDVDQCGSDNLASQKFDLHFFKKIPLGAETSNIMVGETDFLNQMVVVFIRLKEAVILGELTEVPVPTRFVFVMLGPQGSAVKNHEIGRSMATLMSDDVFHDVAYKARNLDDLLAGIDEFLSNCTVLPPAEWDPSIRIEPPKSGPIA--RKVPSMPNGAQALLTASGDGRXXXXXXXXXXXXXXASVVNKLQPVEEESHADPTLRRTGRLFGGLIEDVKRKAPFYLSDFKDAIHVQCFASFFFLYFACLTPIITFGGLLVQATGGYLGAIESILSGTIVGVVYSLFSGQPLTIMGSTGPVLVFESIVYNICERMRWDYLPFRLWIGVWIAAYLFLMVAFDLSALVRYITRFTEESFAALIALIFMVEAFKKLFLIVDYYPIDTRWNIDMIKNRTCECF----PRNATAMDAFFQKNNKPSNVYMPPMLYPVPLNSSVIDIVNNIDWQNISNYHFTWDYKKYRLICTKWGGIWTGSGCGNY--FIPDVFFFSCLLFIGTFVLSYGLKMMRNAQFFPNWVRSLISDFAVMIAISSMTLLDWSLGFHTPKLNVPAKFEPTLGYKMRGWVIPALGKNPWWTIIIAMGPALLAVILIFMDQQITAVIVNRKENKLKKGSGYHXXXXXXXXXXXXXXXXGIPWFVAATVLSINHVMSLKKESENTAPGERPVFLGCREQRVTGTIIFLVIGLSVFLTPLLKRIPMAVLYGVFLFMGVASLKGVQLMQRISLFFMPAKYQPDYIFLRYVPLRRVHXXXXXXXXXXXXXXXXXXXNVMSICFPIMVLALCFVRKGLEYLFTYNELKWLDDIMPNHKKPPQDDNENDIEKCGSTELIKMTETNLEFNSSTNKVIRSNDSGINISEEMGKTA---IWKQLS 3538
            +E +LDRG   +  + +  ++E+E HR+   LYIGVH+P   + + + +R R H    + +  ++D  TE   +       PSQ V FLLG ++DEE   H LF E+DE+ L +  + EWKETARW+KFEEDVE+GGERWSKP+VA+LSL+SLFE+R+CI +   M ++ A++ E I +++L++  +   +  + R+K++  L ++H H ++++       +++P++RS ADIG+K S    +DK       Q Q  N++   + +R                   + + +D            K DLHF KKIP GAE SNI+VGE +FL + VV FIRL  AV+L  L EVP+ TRF+F++LGP G   + HEIGRS+ATLM+D+VFHDVAYKA+   DL+AGIDEFL   TVLPP EWDP+IRIEPPK+ P    RKVP + NG   L                                E   H  P L+RTGR+FGGL  D+KRKAP YLSD+ DA+ +QC ASF FLY AC++P+ITFGGLL +AT G + AIES+   ++ G+ YSLF+GQPLTI+GSTGPVLVFE I++  C+     YL  R+ IG+W A +  L+VA D S+LV YITRFTEE+FA+LI +IF+ EA +KL  + + YP +   +++ +   +C C     P NAT +  + +KN   S                       IDW  +       D K     C +  G + GS CG++  +IPDV F+S +LF  T  +S  LK  + +++FP  VR +ISDFAV I I +M L+D+ LG  +PKL VP  F+PT     RGW+I  LG NPWWT+I+   PALL  ILIFMDQQITAVI+NRKE+KLKKG GYHLDL VV +++ V S++G+PWFVAATVLSI+HV SLK ESE +APGE+P FLG REQR TG +IF+++G SVF+T +LK IPM VLYGVFL+MG +SL+G+Q   R+ LF MPAK+QPD+I+LR+VPLR+VH+FTIIQ+  LVLLWVIKT    +I FP+MVLAL F+RK L+++F+  +L WLDD+MP  KK   +D + +  +C   E   + +  LE +       + + S +NI++EM KT+   +WK L+
Sbjct:   29 EEAVLDRGGTRSMLNTNFEKEELEGHRT---LYIGVHVP---LGRRSHRRHRHHGHRHRKRSRERDSGTEDGRESPSYTDTPSQRVQFLLGMEDDEEHIPHALFTELDEICLKEGEDAEWKETARWLKFEEDVEDGGERWSKPYVATLSLHSLFELRSCILNGTVMLDMRASSLEEIADMVLDQHETSGPLGEEVRKKIRNALLKQHHHQNQKK-----LANRIPIVRSFADIGRKQSEPHSMDKNGQMVSPQTQPINTEGRGEGSR-------------------ENSAVDF----------SKIDLHFMKKIPPGAEASNILVGELEFLEKPVVAFIRLSPAVLLNGLAEVPITTRFLFILLGPMGKGPQYHEIGRSIATLMTDEVFHDVAYKAKERSDLVAGIDEFLDQVTVLPPGEWDPTIRIEPPKNVPSQEKRKVPPLANGGADLGEEE----------------------------EHGGHGGPELQRTGRIFGGLFLDIKRKAPHYLSDYTDALSLQCLASFLFLYCACMSPVITFGGLLGEATEGRISAIESLFGASMTGIAYSLFAGQPLTILGSTGPVLVFEKILFKFCKEYGLSYLSLRVCIGLWTAFFCLLLVATDASSLVCYITRFTEEAFASLICIIFIYEALEKLIHLGETYPFNMHNDLNKLTQYSCVCTIPKEPSNAT-LKYWEEKNITASE----------------------IDWLGL-------DVKG----CVENRGEFVGSACGHHGPYIPDVLFWSVVLFFSTVAMSSFLKEFKTSRYFPTKVRQIISDFAVFITIMTMVLIDYGLGVPSPKLQVPNVFKPT--RDDRGWIISPLGPNPWWTVIVTCIPALLCTILIFMDQQITAVIINRKEHKLKKGCGYHLDLFVVGVMLGVCSVMGLPWFVAATVLSISHVNSLKLESECSAPGEQPKFLGIREQRFTGLMIFVLMGSSVFMTSVLKHIPMPVLYGVFLYMGASSLRGIQFFDRLKLFGMPAKHQPDFIYLRHVPLRKVHMFTIIQLSCLVLLWVIKTSRA-AIVFPMMVLALVFIRKLLDFVFSKRDLSWLDDLMPESKKKKMEDAQQEENQCVLIEDEGIVQVPLEGH------YKDDPSTVNITDEMTKTSFGNVWKGLN 1077          
BLAST of slc4a-1 vs. Ensembl Zebrafish
Match: slc4a7 (solute carrier family 4 member 7 [Source:ZFIN;Acc:ZDB-GENE-140106-104])

HSP 1 Score: 909.827 bits (2350), Expect = 0.000e+0
Identity = 542/1153 (47.01%), Postives = 731/1153 (63.40%), Query Frame = 2
Query:  125 DEPILDRGFQFTHYHPSEDEIEDHRSQRALYIGVHMPPDXXXXXXXXXXXXXXXXXXXXXDKKDYLTEIAEDDTEKAT--DPSQHVMFLLG-EDEDEE--THNLFCEMDELRLDDEGEPEWKETARWIKFEEDVEEGGERWSKPHVASLSLYSLFEVRNCITSAVNMFNVEANNFETIIEIILNKIVSEKKISPDQREKVKEMLQRKHVHLHERRHKSNAKGSQLPLIRSLADIGKKYSSKEVDKVQLQRRNS--DYPTKFTRFDANXXXXXXXXXXXXXYVDKNRIDVDQCGSDNLASQKFDLHFFKKIPLGAETSNIMVGETDFLNQMVVVFIRLKEAVILGELTEVPVPTRFVFVMLGPQGSAVKNHEIGRSMATLMSDDVFHDVAYKARNLDDLLAGIDEFLSNCTVLPPAEWDPSIRIEPPKSGPIA--RKVPSMPNGAQALLTASGDGRXXXXXXXXXXXXXXASVVNKLQPVEEESHADPTLRRTGRLFGGLIEDVKRKAPFYLSDFKDAIHVQCFASFFFLYFACLTPIITFGGLLVQATGGYLGAIESILSGTIVGVVYSLFSGQPLTIMGSTGPVLVFESIVYNICERMRWDYLPFRLWIGVWIAAYLFLMVAFDLSALVRYITRFTEESFAALIALIFMVEAFKKLFLIVDYYPIDTRWNIDMIKNRTCECFPRNATAMDAFFQKNNKPSNVYMPPMLYPVPLNSSVIDIVNNIDWQNISNYHFTWDYKKYRLICTKWGGIWTGSGCGNY--FIPDVFFFSCLLFIGTFVLSYGLKMMRNAQFFPNWVRSLISDFAVMIAISSMTLLDWSLGFHTPKLNVPAKFEPTLGYKMRGWVIPALGKNPWWTIIIAMGPALLAVILIFMDQQITAVIVNRKENKLKKGSGYHXXXXXXXXXXXXXXXXGIPWFVAATVLSINHVMSLKKESENTAPGERPVFLGCREQRVTGTIIFLVIGLSVFLTPLLKRIPMAVLYGVFLFMGVASLKGVQLMQRISLFFMPAKYQPDYIFLRYVPLRRVHXXXXXXXXXXXXXXXXXXXNVMSICFPIMVLALCFVRKGLEYLFTYNELKWLDDIMPNHKKPPQDDNENDIEKCGSTELIKMTETNLEFNSSTN-----KVIR--SNDSGINISEEMGKTAIWK 3529
            DE ++D+G   ++ H +  E E+  S RA+Y+GVH+P        + RRR   +  +    +KD  +E  ED  +  T   PSQ V F+LG ED+DEE   H+LF E+DEL   D    EWKETARW+KFEEDVE+GGERWSKP+VA+LSL+SLFE+R+CI +   M ++ AN+ E I +++L+ +V+ +++    REKV++ + ++H H +E++       +++PL+RS ADIGKK+S        L  RN     P        NS       + +    + + +D            + D++F KKIP GAE SN++VGE DFL + ++ FIRL  AV+L  LTEVPVPTRF+F++LGP G   + HEIGRS+ATLM+D++FHDVAYKA++ +DLL+GIDEFL   TVLPP EWDP+IRIEPPKS P    RK+PSMPNG+                         + V+      +E  HA P L+RTGR+FGGL+ D+KRKAPFY SD +DA  +QC AS  FLY AC++P+ITFGGLL +AT   + AIES+   ++ GV +SLF+GQPLTI+GSTGPVLVFE I++  C      YLP R  IG+W A    L+VA D S+LV YITRFTEE+FAALI +IF+ EA +KLF +   YP +   +++ +   TC+C P + T      Q  N+    Y                  + I+W  ++              C    G + G  CG+   +IPDV F+S +LF  TF LS  LK  +  ++FP  VRS ISDFAV + I  M L+D+ +G  +PKL+VP +FEPT   K RGW+I  LG NP WT+  A  PALL  ILIFMDQQITAVI+NRKE+KLKKG GYHLDLLVVA+++ V SI+G+PWFVAATVLSI+HV SLK ESE +APGE+P FLG REQRVTG +IF+++GLSVF+T +LK IPM VLYGVFL+MGV+SL+G+Q   RI LF MPAK+QPD I+LRYVPL +VH    +  +  ++L  +  ++  ++ FP+MVLAL FVRK L++ FT  EL WLDD+MP  KK  +DD +   ++     +    E  + F+         K I+  ++ S +NIS+EM KTA WK
Sbjct:   43 DEAVVDQGKTSSNIH-TNFEKEELESHRAVYVGVHVP-----LGRQSRRRHRHRGHKHHRKRKDRCSE-REDGRDSPTYDTPSQRVQFILGTEDDDEEHIPHDLFTELDELCFRDGLTCEWKETARWLKFEEDVEDGGERWSKPYVATLSLHSLFELRSCILNGTVMLDMRANSIEEIADMVLDNMVASEQLDESVREKVRDAVLKRHHHQNEKK-----LSNRIPLVRSFADIGKKHSDP-----HLLERNGLLASPQSAPGILENSKSSESRINGTGGSRENSTVDF----------SRVDMNFMKKIPPGAEASNVLVGEVDFLERPIIAFIRLSPAVLLTGLTEVPVPTRFLFLLLGPFGKGAQYHEIGRSIATLMTDEIFHDVAYKAKDRNDLLSGIDEFLDQVTVLPPGEWDPTIRIEPPKSVPSQEKRKMPSMPNGSTP----------------------QSDVIK-----QEAHHAGPELQRTGRIFGGLVLDLKRKAPFYWSDVRDAFSLQCLASILFLYCACMSPVITFGGLLGEATKNNISAIESLFGASLTGVAFSLFAGQPLTILGSTGPVLVFEKILFKFCSDYGLSYLPLRTSIGLWTAFLCLLLVATDASSLVCYITRFTEEAFAALICIIFIYEALEKLFQLGKMYPFNMHDDLNNLTFYTCQCSPPSNTT-QKMEQSWNQSGFTY------------------DTINWTELNVQD-----------CRDLHGEFVGPACGHNGPYIPDVLFWSVILFFTTFFLSSFLKQFKTKRYFPTKVRSSISDFAVFLTIMIMVLVDYLVGIPSPKLHVPDRFEPT--SKNRGWLISPLGDNPTWTLFAAAIPALLCTILIFMDQQITAVIINRKEHKLKKGCGYHLDLLVVAVMLGVCSIMGLPWFVAATVLSISHVNSLKVESECSAPGEQPKFLGIREQRVTGLMIFVLMGLSVFMTSILKFIPMPVLYGVFLYMGVSSLRGIQFFDRIKLFGMPAKHQPDLIYLRYVPLWKVH-IFTLVQLTCLVLLWVIKVSAAAVVFPMMVLALVFVRKLLDFCFTKRELSWLDDLMPESKKKKEDDKKKKAKEEAQRMMEAEEEIEIPFDGGDQLEIPEKTIQISTDPSVVNISDEMAKTAAWK 1108          
BLAST of slc4a-1 vs. Ensembl Zebrafish
Match: slc4a10a (solute carrier family 4 member 10a [Source:ZFIN;Acc:ZDB-GENE-100215-3])

HSP 1 Score: 909.442 bits (2349), Expect = 0.000e+0
Identity = 535/1160 (46.12%), Postives = 736/1160 (63.45%), Query Frame = 2
Query:  125 DEPILDRGFQFTHYHPS--EDEIEDHRSQRALYIGVHMPPDXXXXXXXXXXXXXXXXXXXXXDKKDYLTEIAEDDTEKATDPSQHVMFLLGEDEDEE--THNLFCEMDELRLDDEGEPEWKETARWIKFEEDVEEGGERWSKPHVASLSLYSLFEVRNCITSAVNMFNVEANNFETIIEIILNKIVSEKKISPDQREKVKEMLQRKHVHLHERRHKSNAKGSQLPLIRSLADIGKKYSS-KEVDK------VQLQRRNSDYPTKFTRFDANXXXXXXXXXXXXXYVDKNRIDVDQCGSDNLASQKFDLHFFKKIPLGAETSNIMVGETDFLNQMVVVFIRLKEAVILGELTEVPVPTRFVFVMLGPQGSAVKNHEIGRSMATLMSDDVFHDVAYKARNLDDLLAGIDEFLSNCTVLPPAEWDPSIRIEPPKSGPIA--RKVPSMPNGAQALLTASGDGRXXXXXXXXXXXXXXASVVNKLQPVEEESHADPTLRRTGRLFGGLIEDVKRKAPFYLSDFKDAIHVQCFASFFFLYFACLTPIITFGGLLVQATGGYLGAIESILSGTIVGVVYSLFSGQPLTIMGSTGPVLVFESIVYNICERMRWDYLPFRLWIGVWIAAYLFLMVAFDLSALVRYITRFTEESFAALIALIFMVEAFKKLFLIVDYYPIDTRWNIDMIKNRTCECF----PRNATAMDAFFQKNNKPSNVYMPPMLYPVPLNSSVIDIVNNIDWQNISNYHFTWDYKKYRLICTKWGGIWTGSGCGNY--FIPDVFFFSCLLFIGTFVLSYGLKMMRNAQFFPNWVRSLISDFAVMIAISSMTLLDWSLGFHTPKLNVPAKFEPTLGYKMRGWVIPALGKNPWWTIIIAMGPALLAVILIFMDQQITAVIVNRKENKLKKGSGYHXXXXXXXXXXXXXXXXGIPWFVAATVLSINHVMSLKKESENTAPGERPVFLGCREQRVTGTIIFLVIGLSVFLTPLLKRIPMAVLYGVFLFMGVASLKGVQLMQRISLFFMPAKYQPDYIFLRYVPLRRVHXXXXXXXXXXXXXXXXXXXNVMSICFPIMVLALCFVRKGLEYLFTYNELKWLDDIMPNHKKPPQDDNENDIEKCGSTELIKMTETNLEFNSSTNKVIRSNDSGINISEEMGKTA---IWKQLS 3538
            +E +LDRG   +  + +  ++E+E HR+   LYIGVH+P   + + + +R R H    + +  ++D  TE   +       PSQ V FLLG ++DEE   H LF E+DE+ L +  + EWKETARW+KFEEDVE+GGERWSKP+VA+LSL+SLFE+R+CI +   M ++ A++ E I +++L++  +   +  + R+K++  L ++H H ++++       +++P++RS ADIG+K S    +DK       Q Q  N++   + +R                   + + +D            K DLHF KKIP GAE SNI+VGE +FL + VV FIRL  AV+L  L EVP+ TRF+F++LGP G   + HEIGRS+ATLM+D+VFHDVAYKA+   DL+AGIDEFL   TVLPP EWDP+IRIEPPK+ P    RKVP + NG   L                                E   H  P L+RTGR+FGGL  D+KRKAP YLSD+ DA+ +QC ASF FLY AC++P+ITFGGLL +AT G + AIES+   ++ G+ YSLF+GQPLTI+GSTGPVLVFE I++  C+     YL  R+ IG+W A +  L+VA D S+LV YITRFTEE+FA+LI +IF+ EA +KL  + + YP +   +++ +   +C C     P NAT +  + +KN   S                       IDW  +       D K     C +  G + GS CG++  +IPDV F+S +LF  T  +S  LK  + +++FP  VR +ISDFAV I I +M L+D+ LG  +PKL VP  F+PT     RGW+I  LG NPWWT+I+   PALL  ILIFMDQQITAVI+NRKE+KLKKG GYHLDL VV +++ V S++G+PWFVAATVLSI+HV SLK ESE +APGE+P FLG REQR TG +IF+++G SVF+T +LK IPM VLYGVFL+MG +SL+G+Q   R+ LF MPAK+QPD+I+LR+VPLR+VH+FTIIQ+  LVLLWVIKT    +I FP+MVLAL F+RK L+++F+  +L WLDD+MP  KK   +D + +  +C   E   + +  LE +       + + S +NI++EM KT+   +WK L+
Sbjct:   29 EEAVLDRGGTRSMLNTNFEKEELEGHRT---LYIGVHVP---LGRRSHRRHRHHGHRHRKRSRERDSGTEDGRESPSYTDTPSQRVQFLLGMEDDEEHIPHALFTELDEICLKEGEDAEWKETARWLKFEEDVEDGGERWSKPYVATLSLHSLFELRSCILNGTVMLDMRASSLEEIADMVLDQHETSGPLGEEVRKKIRNALLKQHHHQNQKK-----LANRIPIVRSFADIGRKQSEPHSMDKNGQMVSPQTQPINTEGRGEGSR-------------------ENSAVDFS----------KIDLHFMKKIPPGAEASNILVGELEFLEKPVVAFIRLSPAVLLNGLAEVPITTRFLFILLGPMGKGPQYHEIGRSIATLMTDEVFHDVAYKAKERSDLVAGIDEFLDQVTVLPPGEWDPTIRIEPPKNVPSQEKRKVPPLANGGADLGEEE----------------------------EHGGHGGPELQRTGRIFGGLFLDIKRKAPHYLSDYTDALSLQCLASFLFLYCACMSPVITFGGLLGEATEGRISAIESLFGASMTGIAYSLFAGQPLTILGSTGPVLVFEKILFKFCKEYGLSYLSLRVCIGLWTAFFCLLLVATDASSLVCYITRFTEEAFASLICIIFIYEALEKLIHLGETYPFNMHNDLNKLTQYSCVCTIPKEPSNAT-LKYWEEKNITASE----------------------IDWLGL-------DVKG----CVENRGEFVGSACGHHGPYIPDVLFWSVVLFFSTVAMSSFLKEFKTSRYFPTKVRQIISDFAVFITIMTMVLIDYGLGVPSPKLQVPNVFKPT--RDDRGWIISPLGPNPWWTVIVTCIPALLCTILIFMDQQITAVIINRKEHKLKKGCGYHLDLFVVGVMLGVCSVMGLPWFVAATVLSISHVNSLKLESECSAPGEQPKFLGIREQRFTGLMIFVLMGSSVFMTSVLKHIPMPVLYGVFLYMGASSLRGIQFFDRLKLFGMPAKHQPDFIYLRHVPLRKVHMFTIIQLSCLVLLWVIKTSRA-AIVFPMMVLALVFIRKLLDFVFSKRDLSWLDDLMPESKKKKMEDAQQEENQCVLIEDEGIVQVPLEGH------YKDDPSTVNITDEMTKTSFGNVWKGLN 1077          
BLAST of slc4a-1 vs. Ensembl Zebrafish
Match: slc4a10a (solute carrier family 4 member 10a [Source:ZFIN;Acc:ZDB-GENE-100215-3])

HSP 1 Score: 909.057 bits (2348), Expect = 0.000e+0
Identity = 535/1160 (46.12%), Postives = 736/1160 (63.45%), Query Frame = 2
Query:  125 DEPILDRGFQFTHYHPS--EDEIEDHRSQRALYIGVHMPPDXXXXXXXXXXXXXXXXXXXXXDKKDYLTEIAEDDTEKATDPSQHVMFLLGEDEDEE--THNLFCEMDELRLDDEGEPEWKETARWIKFEEDVEEGGERWSKPHVASLSLYSLFEVRNCITSAVNMFNVEANNFETIIEIILNKIVSEKKISPDQREKVKEMLQRKHVHLHERRHKSNAKGSQLPLIRSLADIGKKYSS-KEVDK------VQLQRRNSDYPTKFTRFDANXXXXXXXXXXXXXYVDKNRIDVDQCGSDNLASQKFDLHFFKKIPLGAETSNIMVGETDFLNQMVVVFIRLKEAVILGELTEVPVPTRFVFVMLGPQGSAVKNHEIGRSMATLMSDDVFHDVAYKARNLDDLLAGIDEFLSNCTVLPPAEWDPSIRIEPPKSGPIA--RKVPSMPNGAQALLTASGDGRXXXXXXXXXXXXXXASVVNKLQPVEEESHADPTLRRTGRLFGGLIEDVKRKAPFYLSDFKDAIHVQCFASFFFLYFACLTPIITFGGLLVQATGGYLGAIESILSGTIVGVVYSLFSGQPLTIMGSTGPVLVFESIVYNICERMRWDYLPFRLWIGVWIAAYLFLMVAFDLSALVRYITRFTEESFAALIALIFMVEAFKKLFLIVDYYPIDTRWNIDMIKNRTCECF----PRNATAMDAFFQKNNKPSNVYMPPMLYPVPLNSSVIDIVNNIDWQNISNYHFTWDYKKYRLICTKWGGIWTGSGCGNY--FIPDVFFFSCLLFIGTFVLSYGLKMMRNAQFFPNWVRSLISDFAVMIAISSMTLLDWSLGFHTPKLNVPAKFEPTLGYKMRGWVIPALGKNPWWTIIIAMGPALLAVILIFMDQQITAVIVNRKENKLKKGSGYHXXXXXXXXXXXXXXXXGIPWFVAATVLSINHVMSLKKESENTAPGERPVFLGCREQRVTGTIIFLVIGLSVFLTPLLKRIPMAVLYGVFLFMGVASLKGVQLMQRISLFFMPAKYQPDYIFLRYVPLRRVHXXXXXXXXXXXXXXXXXXXNVMSICFPIMVLALCFVRKGLEYLFTYNELKWLDDIMPNHKKPPQDDNENDIEKCGSTELIKMTETNLEFNSSTNKVIRSNDSGINISEEMGKTA---IWKQLS 3538
            +E +LDRG   +  + +  ++E+E HR+   LYIGVH+P   + + + +R R H    + +  ++D  TE   +       PSQ V FLLG ++DEE   H LF E+DE+ L +  + EWKETARW+KFEEDVE+GGERWSKP+VA+LSL+SLFE+R+CI +   M ++ A++ E I +++L++  +   +  + R+K++  L ++H H ++++       +++P++RS ADIG+K S    +DK       Q Q  N++   + +R                   + + +D            K DLHF KKIP GAE SNI+VGE +FL + VV FIRL  AV+L  L EVP+ TRF+F++LGP G   + HEIGRS+ATLM+D+VFHDVAYKA+   DL+AGIDEFL   TVLPP EWDP+IRIEPPK+ P    RKVP + NG   L                                E   H  P L+RTGR+FGGL  D+KRKAP YLSD+ DA+ +QC ASF FLY AC++P+ITFGGLL +AT G + AIES+   ++ G+ YSLF+GQPLTI+GSTGPVLVFE I++  C+     YL  R+ IG+W A +  L+VA D S+LV YITRFTEE+FA+LI +IF+ EA +KL  + + YP +   +++ +   +C C     P NAT +  + +KN   S                       IDW  +       D K     C +  G + GS CG++  +IPDV F+S +LF  T  +S  LK  + +++FP  VR +ISDFAV I I +M L+D+ LG  +PKL VP  F+PT     RGW+I  LG NPWWT+I+   PALL  ILIFMDQQITAVI+NRKE+KLKKG GYHLDL VV +++ V S++G+PWFVAATVLSI+HV SLK ESE +APGE+P FLG REQR TG +IF+++G SVF+T +LK IPM VLYGVFL+MG +SL+G+Q   R+ LF MPAK+QPD+I+LR+VPLR+VH+FTIIQ+  LVLLWVIKT    +I FP+MVLAL F+RK L+++F+  +L WLDD+MP  KK   +D + +  +C   E   + +  LE +       + + S +NI++EM KT+   +WK L+
Sbjct:   18 EEAVLDRGGTRSMLNTNFEKEELEGHRT---LYIGVHVP---LGRRSHRRHRHHGHRHRKRSRERDSGTEDGRESPSYTDTPSQRVQFLLGMEDDEEHIPHALFTELDEICLKEGEDAEWKETARWLKFEEDVEDGGERWSKPYVATLSLHSLFELRSCILNGTVMLDMRASSLEEIADMVLDQHETSGPLGEEVRKKIRNALLKQHHHQNQKK-----LANRIPIVRSFADIGRKQSEPHSMDKNGQMVSPQTQPINTEGRGEGSR-------------------ENSAVDFS----------KIDLHFMKKIPPGAEASNILVGELEFLEKPVVAFIRLSPAVLLNGLAEVPITTRFLFILLGPMGKGPQYHEIGRSIATLMTDEVFHDVAYKAKERSDLVAGIDEFLDQVTVLPPGEWDPTIRIEPPKNVPSQEKRKVPPLANGGADLGEEE----------------------------EHGGHGGPELQRTGRIFGGLFLDIKRKAPHYLSDYTDALSLQCLASFLFLYCACMSPVITFGGLLGEATEGRISAIESLFGASMTGIAYSLFAGQPLTILGSTGPVLVFEKILFKFCKEYGLSYLSLRVCIGLWTAFFCLLLVATDASSLVCYITRFTEEAFASLICIIFIYEALEKLIHLGETYPFNMHNDLNKLTQYSCVCTIPKEPSNAT-LKYWEEKNITASE----------------------IDWLGL-------DVKG----CVENRGEFVGSACGHHGPYIPDVLFWSVVLFFSTVAMSSFLKEFKTSRYFPTKVRQIISDFAVFITIMTMVLIDYGLGVPSPKLQVPNVFKPT--RDDRGWIISPLGPNPWWTVIVTCIPALLCTILIFMDQQITAVIINRKEHKLKKGCGYHLDLFVVGVMLGVCSVMGLPWFVAATVLSISHVNSLKLESECSAPGEQPKFLGIREQRFTGLMIFVLMGSSVFMTSVLKHIPMPVLYGVFLYMGASSLRGIQFFDRLKLFGMPAKHQPDFIYLRHVPLRKVHMFTIIQLSCLVLLWVIKTSRA-AIVFPMMVLALVFIRKLLDFVFSKRDLSWLDDLMPESKKKKMEDAQQEENQCVLIEDEGIVQVPLEGH------YKDDPSTVNITDEMTKTSFGNVWKGLN 1066          
BLAST of slc4a-1 vs. Ensembl Xenopus
Match: crhbp (corticotropin releasing hormone binding protein [Source:Xenbase;Acc:XB-GENE-486316])

HSP 1 Score: 947.577 bits (2448), Expect = 0.000e+0
Identity = 545/1152 (47.31%), Postives = 738/1152 (64.06%), Query Frame = 2
Query:  125 DEPILDRG--FQFTHYHPSEDEIEDHRSQRALYIGVHMPPDXXXXXXXXXXXXXXXXXXXXXDKKDYLTEIAEDDTEKATDPSQHVMFLLGEDEDEE--THNLFCEMDELRLDDEGEPEWKETARWIKFEEDVEEGGERWSKPHVASLSLYSLFEVRNCITSAVNMFNVEANNFETIIEIILNKIVSEKKISPDQREKVKEMLQRKHVHLHERRHKSNAKGSQLPLIRSLADIGKKYSSKEV-DKVQLQRRNSDYPTKFTRFDANXXXXXXXXXXXXXYVDKNRIDVDQCGSDNLASQKFDLHFFKKIPLGAETSNIMVGETDFLNQMVVVFIRLKEAVILGELTEVPVPTRFVFVMLGPQGSAVKNHEIGRSMATLMSDDVFHDVAYKARNLDDLLAGIDEFLSNCTVLPPAEWDPSIRIEPPKSGPIA--RKVPSMPNGAQALLTASGDGRXXXXXXXXXXXXXXASVVNKLQPVEEESHADPTLRRTGRLFGGLIEDVKRKAPFYLSDFKDAIHVQCFASFFFLYFACLTPIITFGGLLVQATGGYLGAIESILSGTIVGVVYSLFSGQPLTIMGSTGPVLVFESIVYNICERMRWDYLPFRLWIGVWIAAYLFLMVAFDLSALVRYITRFTEESFAALIALIFMVEAFKKLFLIVDYYPIDTRWNIDMIKNRTCECF----PRNATAMDAFFQKNNKPSNVYMPPMLYPVPLNSSVIDIVNNIDWQNISNYHFTWDYKKYRLICTKWGGIWTGSGCGNY--FIPDVFFFSCLLFIGTFVLSYGLKMMRNAQFFPNWVRSLISDFAVMIAISSMTLLDWSLGFHTPKLNVPAKFEPTLGYKMRGWVIPALGKNPWWTIIIAMGPALLAVILIFMDQQITAVIVNRKENKLKKGSGYHXXXXXXXXXXXXXXXXGIPWFVAATVLSINHVMSLKKESENTAPGERPVFLGCREQRVTGTIIFLVIGLSVFLTPLLKRIPMAVLYGVFLFMGVASLKGVQLMQRISLFFMPAKYQPDYIFLRYVPLRRVHXXXXXXXXXXXXXXXXXXXNVMSICFPIMVLALCFVRKGLEYLFTYNELKWLDDIMPNHKKPPQDDNENDIEKCGSTELIKMTE-TNLEFNSSTNKVIRSNDSGINISEEMGKTAIWKQLS 3538
            +E I+D+G      + H  ++E+E HR+   LY+GV MP   + + + +  R H +  + +   K  + E   D++     PSQ V F+LG ++DEE   H LF E+DE+ + +  + EWKETARW+KFEEDVE+GGERWSKP+VA+LSL+SLFE+R+CI +     ++ AN  E + ++IL+   S  ++  + R KVKE L +KH H  E++     + + +P++RS A++GKK S   + DK  L    S  PT  T                        +DV   GS    S   DLHF KKIP GAE SN++VGE DFL + +V F+RL  AV+L  LTEVP+PTRF+F++LGP G A + HEIGRSMAT+M+D++FHDVAYKA++  DLLAGIDEFL   TVLPP EWDPSIRIEPPK+ P    RK+P +PNG                             V  ++P  E  H+ P L+RTG +FGGL+ D+KRKAPFYLSD++DA+ +QC ASF FLY AC++P+ITFGGLL +AT G + AIES+   ++ G+ YSLF+GQPLTI+GSTGPVLVFE I++  C+     YL  R  IG+W A     +VA D S+LV YITRFTEE+FA+LI +IF+ EA +KL  + + YP++    +D +    C+C     P N T +  ++++NN                       +   +W N +              C K  G + G  CG++  + PDV F+SC+LF  TF LS  LK  + +++FP  VRS++SDFAV + I +M +LD+ +G  +PKL VP +F+PT     RGW++  +G NPWWT+   + PALL  ILIFMDQQITAVI+NRKE+KLKKG GYHLDLLVV +++ + SI+G+PWFVAATVLSI HV SLK ESE +APGE+P FLG REQRVTG +IF+++G SVF+T +LK IPM VLYGVFL+MGV+SL+G+Q   R+ LF MPAK+QPD+ +LR+VPLR+VHLFTIIQ+  LVLLWVIK     +I FP+MVLAL FVRK +++ F+  EL WLDD+MP  KK   DD +N   K    E++   E   ++    T K++ S+ S INIS+EM KT +WK LS
Sbjct:    6 EEAIVDQGGTSSVLNIHYEKEELEGHRT---LYVGVRMP---LGRQSHRHHRTHGQKHRKRDRMKGVIQEEGHDESSAHDTPSQRVQFILGTEDDEEHVPHELFTELDEICVKEGEDAEWKETARWLKFEEDVEDGGERWSKPYVATLSLHSLFELRSCIINGTVQLDMRANTIEEVADMILDHQDSANELGDNIRVKVKEALLKKHHHQIEKK-----RNNLIPMVRSFAEVGKKQSEPHLLDKNSLSV--SPQPTPST------------------------LDVKNGGSHE-NSSSVDLHFMKKIPTGAEASNVLVGELDFLERPIVAFVRLSPAVLLTGLTEVPIPTRFLFILLGPVGKAQQYHEIGRSMATIMTDEIFHDVAYKAKDRGDLLAGIDEFLDQVTVLPPGEWDPSIRIEPPKNVPSQEKRKMPGVPNGN----------------------------VCHVEPEPEPEHSGPELQRTGMIFGGLVADIKRKAPFYLSDYRDALSLQCVASFLFLYCACMSPVITFGGLLGEATEGRISAIESLFGASMTGIAYSLFAGQPLTILGSTGPVLVFEKILFKFCKEYGLSYLSLRACIGLWTAFLCIFLVATDASSLVCYITRFTEEAFASLICIIFIYEAIEKLIHLGETYPVNMHSQLDKLTLYYCKCAAPASPTNDTLL--YWRENNI---------------------TITEAEWANFTVSE-----------CNKMHGEFVGPACGHHGPYTPDVLFWSCILFFTTFALSSVLKTFKTSRYFPTKVRSMVSDFAVFLTILTMVVLDYVIGVPSPKLQVPNEFKPT--RDDRGWLVNPIGPNPWWTVFPTIIPALLCTILIFMDQQITAVIINRKEHKLKKGCGYHLDLLVVGLMLGICSIMGLPWFVAATVLSITHVNSLKLESECSAPGEQPKFLGIREQRVTGLMIFVLMGCSVFMTTVLKFIPMPVLYGVFLYMGVSSLRGIQFFDRLLLFAMPAKHQPDFSYLRHVPLRKVHLFTIIQLTCLVLLWVIKASPA-AIVFPMMVLALVFVRKVMDFCFSDRELSWLDDLMPESKKKKLDDAKN---KAKELEMLHEGEDKGVQLPLETRKLL-SDPSEINISDEMPKTTVWKALS 1050          
BLAST of slc4a-1 vs. Ensembl Xenopus
Match: tbx5 (T-box 5 [Source:Xenbase;Acc:XB-GENE-486855])

HSP 1 Score: 943.34 bits (2437), Expect = 0.000e+0
Identity = 549/1155 (47.53%), Postives = 739/1155 (63.98%), Query Frame = 2
Query:  125 DEPILDRG----FQFTHYHPSEDEIEDHRSQRALYIGVHMPPDXXXXXXXXXXXXXXXXXXXXXDKKDYLTEIAEDDTEKAT--DPSQHVMFLLG-EDEDEE--THNLFCEMDELRLDDEGEPEWKETARWIKFEEDVEEGGERWSKPHVASLSLYSLFEVRNCITSAVNMFNVEANNFETIIEIILNKIVSEKKISPDQREKVKEMLQRKHVHLHERRHKSNAKGSQLPLIRSLADIGKKYSS-KEVDKVQLQRRNSDYPTKFTRFDANXXXXXXXXXXXXXYVDKNRIDVDQCGSDNLASQKFDLHFFKKIPLGAETSNIMVGETDFLNQMVVVFIRLKEAVILGELTEVPVPTRFVFVMLGPQGSAVKNHEIGRSMATLMSDDVFHDVAYKARNLDDLLAGIDEFLSNCTVLPPAEWDPSIRIEPPKSGPIA--RKVPSMPNGAQALLTASGDGRXXXXXXXXXXXXXXASVVNKLQPVEEESHADPTLRRTGRLFGGLIEDVKRKAPFYLSDFKDAIHVQCFASFFFLYFACLTPIITFGGLLVQATGGYLGAIESILSGTIVGVVYSLFSGQPLTIMGSTGPVLVFESIVYNICERMRWDYLPFRLWIGVWIAAYLFLMVAFDLSALVRYITRFTEESFAALIALIFMVEAFKKLFLIVDYYPIDTRWNIDMIKNRTCECF----PRNATAMDAFFQKNNKPSNVYMPPMLYPVPLNSSVIDIVNNIDWQNISNYHFTWDYKKYRLICTKWGGIWTGSGCGNY--FIPDVFFFSCLLFIGTFVLSYGLKMMRNAQFFPNWVRSLISDFAVMIAISSMTLLDWSLGFHTPKLNVPAKFEPTLGYKMRGWVIPALGKNPWWTIIIAMGPALLAVILIFMDQQITAVIVNRKENKLKKGSGYHXXXXXXXXXXXXXXXXGIPWFVAATVLSINHVMSLKKESENTAPGERPVFLGCREQRVTGTIIFLVIGLSVFLTPLLKRIPMAVLYGVFLFMGVASLKGVQLMQRISLFFMPAKYQPDYIFLRYVPLRRVHXXXXXXXXXXXXXXXXXXXNVMSICFPIMVLALCFVRKGLEYLFTYNELKWLDDIMPNHKKPPQDDNENDIEKCGSTELIKMTETNLEFNSSTNKVIRSNDSGINISEEMGKTAIWKQL 3535
            +E ++DRG       TH+     E ED    R L+IGVH+P        R R R HK  K+ +           ED  E  T   PSQ V F+LG ED+DEE   H+LF E+DE+ L +  + EW+E ARW+KFEEDVE+GGERWSKP+VA+LSL+SLFE+R+CI     + ++ AN  E I ++IL++ V+  ++S D R +V E L ++H H ++++       +++P++RS ADIGKK S    +DK   Q  +                             +++ DV +  S  L   KFDLHF KKIP GAE SNI+VGE +FL++ +V F+RL  AV+L  LTEVP+P+RF+F++LGP G   + HEIGRS+ATLM+D+VFHDVAYKA++ +DL+AGIDEFL   TVLPP EWDP+IRIEPPK+ P    RK P +PNG  AL                             +P E   H+ P L RTGRLFGGL+ DVKRKAPF+ SDFKDA  +QC AS  FLY AC++P+ITFGGLL +AT G + AIES+   ++ G+ +SLF GQPLTI+GSTGPVLVFE I++  C+     YL  R  IG+W A     +VA D S+LV YITRFTEE+FAALI +IF+ EA +KLF + + YPI+   N++++   +C C     P N T    ++Q +N  +                     + I W N+     T D       C K+ G + G  CG+   ++PDV F+S +LF  T ++S  LK  + +++FP  VRS +SDFAV + I +M L+D+ +G  +PKL VP +F+PT     RGW++  LG+NPWWT++ A+ P+LL  ILIFMDQQITAVI+NRKE+KLKKG GYHLDLL+V I++ V S++G+PWFVAATVLSI HV SLK ESE +APGE+P FLG REQRVTG +IF+++G SVF+T +L+ IPM VLYGVFL+MG +SLKG+Q   RI L++MPAK+QPD+I+LR+VPLR+VHLFTIIQ+  L+LLWVIK     +I FP+MVLAL FVRK +++ FT  EL WLDD+MP  KK   +D + + E+   + L+   E  ++     N   R + S INIS+EM KT++WK L
Sbjct:   19 EEAVVDRGGTRSLLKTHF-----EKEDLEGHRTLFIGVHVPLGGRKSHRRHRHRGHKHRKRDRERDSGL-----EDGRESPTYDTPSQRVQFILGTEDDDEEHIPHDLFTELDEICLREGDDAEWREMARWLKFEEDVEDGGERWSKPYVATLSLHSLFELRSCILHGTVLLDMRANTLEEIADMILDQQVASGQLSEDVRHRVHEALLKQHHHQNQKK-----LSNRIPIVRSFADIGKKQSEPHSMDKTAGQLVSPQSAPSCI---------------------EHKNDVSRENS-TLDVTKFDLHFMKKIPPGAEASNILVGELEFLDRAIVAFVRLSPAVLLSGLTEVPIPSRFLFILLGPLGKGQQYHEIGRSIATLMTDEVFHDVAYKAKDRNDLVAGIDEFLDQVTVLPPGEWDPTIRIEPPKNVPSQEKRKTPGVPNGTAALG----------------------------EPEEHGGHSGPELERTGRLFGGLVLDVKRKAPFFWSDFKDAFSLQCLASILFLYCACMSPVITFGGLLGEATEGRISAIESLFGASMTGIAFSLFGGQPLTILGSTGPVLVFEKILFKFCKDYDLSYLSLRASIGLWTAFNCIFLVATDASSLVCYITRFTEEAFAALICIIFIYEALEKLFHLGETYPINMNNNLELLTQYSCGCMEPENPSNKTL--TYWQSSNITA---------------------SEISWNNL-----TVD------ACHKFHGDFVGRACGHEGPYVPDVLFWSVILFFATVIMSSTLKQFKTSRYFPTKVRSHVSDFAVFLTILTMVLVDFCIGIPSPKLQVPNEFKPT--RDDRGWIVNPLGRNPWWTVVAAIIPSLLCTILIFMDQQITAVIINRKEHKLKKGCGYHLDLLMVGIMLGVCSVMGLPWFVAATVLSITHVNSLKLESECSAPGEQPKFLGIREQRVTGLMIFVLMGSSVFMTRILQFIPMPVLYGVFLYMGSSSLKGIQFFDRILLYWMPAKHQPDFIYLRHVPLRKVHLFTIIQLSCLILLWVIKASRA-AIVFPMMVLALVFVRKLMDFFFTKRELSWLDDLMPESKKKKLEDAQKEEEQ---SMLVLEDEVTVQLPLEEN--FREDPSAINISDEMVKTSVWKTL 1066          
BLAST of slc4a-1 vs. Ensembl Xenopus
Match: tbx5 (T-box 5 [Source:Xenbase;Acc:XB-GENE-486855])

HSP 1 Score: 943.34 bits (2437), Expect = 0.000e+0
Identity = 549/1155 (47.53%), Postives = 739/1155 (63.98%), Query Frame = 2
Query:  125 DEPILDRG----FQFTHYHPSEDEIEDHRSQRALYIGVHMPPDXXXXXXXXXXXXXXXXXXXXXDKKDYLTEIAEDDTEKAT--DPSQHVMFLLG-EDEDEE--THNLFCEMDELRLDDEGEPEWKETARWIKFEEDVEEGGERWSKPHVASLSLYSLFEVRNCITSAVNMFNVEANNFETIIEIILNKIVSEKKISPDQREKVKEMLQRKHVHLHERRHKSNAKGSQLPLIRSLADIGKKYSS-KEVDKVQLQRRNSDYPTKFTRFDANXXXXXXXXXXXXXYVDKNRIDVDQCGSDNLASQKFDLHFFKKIPLGAETSNIMVGETDFLNQMVVVFIRLKEAVILGELTEVPVPTRFVFVMLGPQGSAVKNHEIGRSMATLMSDDVFHDVAYKARNLDDLLAGIDEFLSNCTVLPPAEWDPSIRIEPPKSGPIA--RKVPSMPNGAQALLTASGDGRXXXXXXXXXXXXXXASVVNKLQPVEEESHADPTLRRTGRLFGGLIEDVKRKAPFYLSDFKDAIHVQCFASFFFLYFACLTPIITFGGLLVQATGGYLGAIESILSGTIVGVVYSLFSGQPLTIMGSTGPVLVFESIVYNICERMRWDYLPFRLWIGVWIAAYLFLMVAFDLSALVRYITRFTEESFAALIALIFMVEAFKKLFLIVDYYPIDTRWNIDMIKNRTCECF----PRNATAMDAFFQKNNKPSNVYMPPMLYPVPLNSSVIDIVNNIDWQNISNYHFTWDYKKYRLICTKWGGIWTGSGCGNY--FIPDVFFFSCLLFIGTFVLSYGLKMMRNAQFFPNWVRSLISDFAVMIAISSMTLLDWSLGFHTPKLNVPAKFEPTLGYKMRGWVIPALGKNPWWTIIIAMGPALLAVILIFMDQQITAVIVNRKENKLKKGSGYHXXXXXXXXXXXXXXXXGIPWFVAATVLSINHVMSLKKESENTAPGERPVFLGCREQRVTGTIIFLVIGLSVFLTPLLKRIPMAVLYGVFLFMGVASLKGVQLMQRISLFFMPAKYQPDYIFLRYVPLRRVHXXXXXXXXXXXXXXXXXXXNVMSICFPIMVLALCFVRKGLEYLFTYNELKWLDDIMPNHKKPPQDDNENDIEKCGSTELIKMTETNLEFNSSTNKVIRSNDSGINISEEMGKTAIWKQL 3535
            +E ++DRG       TH+     E ED    R L+IGVH+P        R R R HK  K+ +           ED  E  T   PSQ V F+LG ED+DEE   H+LF E+DE+ L +  + EW+E ARW+KFEEDVE+GGERWSKP+VA+LSL+SLFE+R+CI     + ++ AN  E I ++IL++ V+  ++S D R +V E L ++H H ++++       +++P++RS ADIGKK S    +DK   Q  +                             +++ DV +  S  L   KFDLHF KKIP GAE SNI+VGE +FL++ +V F+RL  AV+L  LTEVP+P+RF+F++LGP G   + HEIGRS+ATLM+D+VFHDVAYKA++ +DL+AGIDEFL   TVLPP EWDP+IRIEPPK+ P    RK P +PNG  AL                             +P E   H+ P L RTGRLFGGL+ DVKRKAPF+ SDFKDA  +QC AS  FLY AC++P+ITFGGLL +AT G + AIES+   ++ G+ +SLF GQPLTI+GSTGPVLVFE I++  C+     YL  R  IG+W A     +VA D S+LV YITRFTEE+FAALI +IF+ EA +KLF + + YPI+   N++++   +C C     P N T    ++Q +N  +                     + I W N+     T D       C K+ G + G  CG+   ++PDV F+S +LF  T ++S  LK  + +++FP  VRS +SDFAV + I +M L+D+ +G  +PKL VP +F+PT     RGW++  LG+NPWWT++ A+ P+LL  ILIFMDQQITAVI+NRKE+KLKKG GYHLDLL+V I++ V S++G+PWFVAATVLSI HV SLK ESE +APGE+P FLG REQRVTG +IF+++G SVF+T +L+ IPM VLYGVFL+MG +SLKG+Q   RI L++MPAK+QPD+I+LR+VPLR+VHLFTIIQ+  L+LLWVIK     +I FP+MVLAL FVRK +++ FT  EL WLDD+MP  KK   +D + + E+   + L+   E  ++     N   R + S INIS+EM KT++WK L
Sbjct:   19 EEAVVDRGGTRSLLKTHF-----EKEDLEGHRTLFIGVHVPLGGRKSHRRHRHRGHKHRKRDRERDSGL-----EDGRESPTYDTPSQRVQFILGTEDDDEEHIPHDLFTELDEICLREGDDAEWREMARWLKFEEDVEDGGERWSKPYVATLSLHSLFELRSCILHGTVLLDMRANTLEEIADMILDQQVASGQLSEDVRHRVHEALLKQHHHQNQKK-----LSNRIPIVRSFADIGKKQSEPHSMDKTAGQLVSPQSAPSCI---------------------EHKNDVSRENS-TLDVTKFDLHFMKKIPPGAEASNILVGELEFLDRAIVAFVRLSPAVLLSGLTEVPIPSRFLFILLGPLGKGQQYHEIGRSIATLMTDEVFHDVAYKAKDRNDLVAGIDEFLDQVTVLPPGEWDPTIRIEPPKNVPSQEKRKTPGVPNGTAALG----------------------------EPEEHGGHSGPELERTGRLFGGLVLDVKRKAPFFWSDFKDAFSLQCLASILFLYCACMSPVITFGGLLGEATEGRISAIESLFGASMTGIAFSLFGGQPLTILGSTGPVLVFEKILFKFCKDYDLSYLSLRASIGLWTAFNCIFLVATDASSLVCYITRFTEEAFAALICIIFIYEALEKLFHLGETYPINMNNNLELLTQYSCGCMEPENPSNKTL--TYWQSSNITA---------------------SEISWNNL-----TVD------ACHKFHGDFVGRACGHEGPYVPDVLFWSVILFFATVIMSSTLKQFKTSRYFPTKVRSHVSDFAVFLTILTMVLVDFCIGIPSPKLQVPNEFKPT--RDDRGWIVNPLGRNPWWTVVAAIIPSLLCTILIFMDQQITAVIINRKEHKLKKGCGYHLDLLMVGIMLGVCSVMGLPWFVAATVLSITHVNSLKLESECSAPGEQPKFLGIREQRVTGLMIFVLMGSSVFMTRILQFIPMPVLYGVFLYMGSSSLKGIQFFDRILLYWMPAKHQPDFIYLRHVPLRKVHLFTIIQLSCLILLWVIKASRA-AIVFPMMVLALVFVRKLMDFFFTKRELSWLDDLMPESKKKKLEDAQKEEEQ---SMLVLEDEVTVQLPLEEN--FREDPSAINISDEMVKTSVWKTL 1066          
BLAST of slc4a-1 vs. Ensembl Xenopus
Match: crhbp (corticotropin releasing hormone binding protein [Source:Xenbase;Acc:XB-GENE-486316])

HSP 1 Score: 936.406 bits (2419), Expect = 0.000e+0
Identity = 525/1103 (47.60%), Postives = 711/1103 (64.46%), Query Frame = 2
Query:  311 KDYLTEIAEDDTEKATDPSQHVMFLLGEDEDEE--THNLFCEMDELRLDDEGEPEWKETARWIKFEEDVEEGGERWSKPHVASLSLYSLFEVRNCITSAVNMFNVEANNFETIIEIILNKIVSEKKISPDQREKVKEMLQRKHVHLHERRHKSNAKGSQLPLIRSLADIGKKYSSKEV-DKVQLQRRNSDYPTKFTRFDANXXXXXXXXXXXXXYVDKNRIDVDQCGSDNLAS---------QKFDLHFFKKIPLGAETSNIMVGETDFLNQMVVVFIRLKEAVILGELTEVPVPTRFVFVMLGPQGSAVKNHEIGRSMATLMSDDVFHDVAYKARNLDDLLAGIDEFLSNCTVLPPAEWDPSIRIEPPKSGPIA--RKVPSMPNGAQALLTASGDGRXXXXXXXXXXXXXXASVVNKLQPVEEESHADPTLRRTGRLFGGLIEDVKRKAPFYLSDFKDAIHVQCFASFFFLYFACLTPIITFGGLLVQATGGYLGAIESILSGTIVGVVYSLFSGQPLTIMGSTGPVLVFESIVYNICERMRWDYLPFRLWIGVWIAAYLFLMVAFDLSALVRYITRFTEESFAALIALIFMVEAFKKLFLIVDYYPIDTRWNIDMIKNRTCECF----PRNATAMDAFFQKNNKPSNVYMPPMLYPVPLNSSVIDIVNNIDWQNISNYHFTWDYKKYRLICTKWGGIWTGSGCGNY--FIPDVFFFSCLLFIGTFVLSYGLKMMRNAQFFPNWVRSLISDFAVMIAISSMTLLDWSLGFHTPKLNVPAKFEPTLGYKMRGWVIPALGKNPWWTIIIAMGPALLAVILIFMDQQITAVIVNRKENKLKKGSGYHXXXXXXXXXXXXXXXXGIPWFVAATVLSINHVMSLKKESENTAPGERPVFLGCREQRVTGTIIFLVIGLSVFLTPLLKRIPMAVLYGVFLFMGVASLKGVQLMQRISLFFMPAKYQPDYIFLRYVPLRRVHXXXXXXXXXXXXXXXXXXXNVMSICFPIMVLALCFVRKGLEYLFTYNELKWLDDIMPNHKKPPQDDNENDIEKC-----GSTELIKMTETNLEFNSS--TNKVIRSNDSGINISEEMGKTAIWKQLS 3538
            K  + E   D++     PSQ V F+LG ++DEE   H LF E+DE+ + +  + EWKETARW+KFEEDVE+GGERWSKP+VA+LSL+SLFE+R+CI +     ++ AN  E + ++IL+   S  ++  + R KVKE L +KH H  E++     + + +P++RS A++GKK S   + DK  L       P+     +  S            + + + +D+ +  SD  +S          K DLHF KKIP GAE SN++VGE DFL + +V F+RL  AV+L  LTEVP+PTRF+F++LGP G A + HEIGRSMAT+M+D++FHDVAYKA++  DLLAGIDEFL   TVLPP EWDPSIRIEPPK+ P    RK+P +PNG                             V  ++P  E  H+ P L+RTG +FGGL+ D+KRKAPFYLSD++DA+ +QC ASF FLY AC++P+ITFGGLL +AT G + AIES+   ++ G+ YSLF+GQPLTI+GSTGPVLVFE I++  C+     YL  R  IG+W A     +VA D S+LV YITRFTEE+FA+LI +IF+ EA +KL  + + YP++    +D +    C+C     P N T +  ++++NN                       +   +W N +              C K  G + G  CG++  + PDV F+SC+LF  TF LS  LK  + +++FP  VRS++SDFAV + I +M +LD+ +G  +PKL VP +F+PT     RGW++  +G NPWWT+   + PALL  ILIFMDQQITAVI+NRKE+KLKKG GYHLDLLVV +++ + SI+G+PWFVAATVLSI HV SLK ESE +APGE+P FLG REQRVTG +IF+++G SVF+T +LK IPM VLYGVFL+MGV+SL+G+Q   R+ LF MPAK+QPD+ +LR+VPLR+VHLFTIIQ+  LVLLWVIK     +I FP+MVLAL FVRK +++ F+  EL WLDD+MP  KK   DD +N  ++      G  + +++     +  SS   N   R + S INIS+EM KT +WK LS
Sbjct:    2 KGVIQEEGHDESSAHDTPSQRVQFILGTEDDEEHVPHELFTELDEICVKEGEDAEWKETARWLKFEEDVEDGGERWSKPYVATLSLHSLFELRSCIINGTVQLDMRANTIEEVADMILDHQDSANELGDNIRVKVKEALLKKHHHQIEKK-----RNNLIPMVRSFAEVGKKQSEPHLLDKNSLSVSPQPTPSTLDVKNGGS------------HENSSSVDLSKVMSDLHSSFYLFCCLMLSKVDLHFMKKIPTGAEASNVLVGELDFLERPIVAFVRLSPAVLLTGLTEVPIPTRFLFILLGPVGKAQQYHEIGRSMATIMTDEIFHDVAYKAKDRGDLLAGIDEFLDQVTVLPPGEWDPSIRIEPPKNVPSQEKRKMPGVPNGN----------------------------VCHVEPEPEPEHSGPELQRTGMIFGGLVADIKRKAPFYLSDYRDALSLQCVASFLFLYCACMSPVITFGGLLGEATEGRISAIESLFGASMTGIAYSLFAGQPLTILGSTGPVLVFEKILFKFCKEYGLSYLSLRACIGLWTAFLCIFLVATDASSLVCYITRFTEEAFASLICIIFIYEAIEKLIHLGETYPVNMHSQLDKLTLYYCKCAAPASPTNDTLL--YWRENNI---------------------TITEAEWANFTVSE-----------CNKMHGEFVGPACGHHGPYTPDVLFWSCILFFTTFALSSVLKTFKTSRYFPTKVRSMVSDFAVFLTILTMVVLDYVIGVPSPKLQVPNEFKPT--RDDRGWLVNPIGPNPWWTVFPTIIPALLCTILIFMDQQITAVIINRKEHKLKKGCGYHLDLLVVGLMLGICSIMGLPWFVAATVLSITHVNSLKLESECSAPGEQPKFLGIREQRVTGLMIFVLMGCSVFMTTVLKFIPMPVLYGVFLYMGVSSLRGIQFFDRLLLFAMPAKHQPDFSYLRHVPLRKVHLFTIIQLTCLVLLWVIKASPA-AIVFPMMVLALVFVRKVMDFCFSDRELSWLDDLMPESKKKKLDDAKNKAKELEMLHEGEDKGVQLPLETRKLLSSPGKNNNSRGDPSEINISDEMPKTTVWKALS 1022          
BLAST of slc4a-1 vs. Ensembl Xenopus
Match: crhbp (corticotropin releasing hormone binding protein [Source:Xenbase;Acc:XB-GENE-486316])

HSP 1 Score: 932.554 bits (2409), Expect = 0.000e+0
Identity = 522/1088 (47.98%), Postives = 699/1088 (64.25%), Query Frame = 2
Query:  311 KDYLTEIAEDDTEKATDPSQHVMFLLGEDEDEE--THNLFCEMDELRLDDEGEPEWKETARWIKFEEDVEEGGERWSKPHVASLSLYSLFEVRNCITSAVNMFNVEANNFETIIEIILNKIVSEKKISPDQREKVKEMLQRKHVHLHERRHKSNAKGSQLPLIRSLADIGKKYSSKEVDKVQLQRRNSDYPTKFTRFDANXXXXXXXXXXXXXYVDKNRIDVDQCGSDNLASQKFDLHFFKKIPLGAETSNIMVGETDFLNQMVVVFIRLKEAVILGELTEVPVPTRFVFVMLGPQGSAVKNHEIGRSMATLMSDDVFHDVAYKARNLDDLLAGIDEFLSNCTVLPPAEWDPSIRIEPPKSGPIA--RKVPSMPNGAQALLTASGDGRXXXXXXXXXXXXXXASVVNKLQPVEEESHADPTLRRTGRLFGGLIEDVKRKAPFYLSDFKDAIHVQCFASFFFLYFACLTPIITFGGLLVQATGGYLGAIESILSGTIVGVVYSLFSGQPLTIMGSTGPVLVFESIVYNICERMRWDYLPFRLWIGVWIAAYLFLMVAFDLSALVRYITRFTEESFAALIALIFMVEAFKKLFLIVDYYPIDTRWNIDMIKNRTCECF----PRNATAMDAFFQKNNKPSNVYMPPMLYPVPLNSSVIDIVNNIDWQNISNYHFTWDYKKYRLICTKWGGIWTGSGCGNY--FIPDVFFFSCLLFIGTFVLSYGLKMMRNAQFFPNWVRSLISDFAVMIAISSMTLLDWSLGFHTPKLNVPAKFEPTLGYKMRGWVIPALGKNPWWTIIIAMGPALLAVILIFMDQQITAVIVNRKENKLKKGSGYHXXXXXXXXXXXXXXXXGIPWFVAATVLSINHVMSLKKESENTAPGERPVFLGCREQRVTGTIIFLVIGLSVFLTPLLKRIPMAVLYGVFLFMGVASLKGVQLMQRISLFFMPAKYQPDYIFLRYVPLRRVHXXXXXXXXXXXXXXXXXXXNVMSICFPIMVLALCFVRKGLEYLFTYNELKWLDDIMPNHKKPPQDDNENDIEKCGSTELIKMTETNLEFNSS--TNKVIRSNDSGINISEEMGKTAIWKQLS 3538
            K  + E   D++     PSQ V F+LG ++DEE   H LF E+DE+ + +  + EWKETARW+KFEEDVE+GGERWSKP+VA+LSL+SLFE+R+CI +     ++ AN  E + ++IL+   S  ++  + R KVKE L +KH H  E++     + + +P++RS A++GKK S        L  +NS   +       N                 + +DV   GS    S   DLHF KKIP GAE SN++VGE DFL + +V F+RL  AV+L  LTEVP+PTRF+F++LGP G A + HEIGRSMAT+M+D++FHDVAYKA++  DLLAGIDEFL   TVLPP EWDPSIRIEPPK+ P    RK+P +PNG                             V  ++P  E  H+ P L+RTG +FGGL+ D+KRKAPFYLSD++DA+ +QC ASF FLY AC++P+ITFGGLL +AT G + AIES+   ++ G+ YSLF+GQPLTI+GSTGPVLVFE I++  C+     YL  R  IG+W A     +VA D S+LV YITRFTEE+FA+LI +IF+ EA +KL  + + YP++    +D +    C+C     P N T +  ++++NN                       +   +W N +              C K  G + G  CG++  + PDV F+SC+LF  TF LS  LK  + +++FP  VRS++SDFAV + I +M +LD+ +G  +PKL VP +F+PT     RGW++  +G NPWWT+   + PALL  ILIFMDQQITAVI+NRKE+KLKKG GYHLDLLVV +++ + SI+G+PWFVAATVLSI HV SLK ESE +APGE+P FLG REQRVTG +IF+++G SVF+T +LK IPM VLYGVFL+MGV+SL+G+Q   R+ LF MPAK+QPD+ +LR+VPLR+VHLFTIIQ+  LVLLWVIK     +I FP+MVLAL FVRK +++ F+  EL WLDD+MP  KK   DD+   +         ++     +  SS   N   R + S INIS+EM KT +WK LS
Sbjct:    2 KGVIQEEGHDESSAHDTPSQRVQFILGTEDDEEHVPHELFTELDEICVKEGEDAEWKETARWLKFEEDVEDGGERWSKPYVATLSLHSLFELRSCIINGTVQLDMRANTIEEVADMILDHQDSANELGDNIRVKVKEALLKKHHHQIEKK-----RNNLIPMVRSFAEVGKKQSEP-----HLLDKNSKSASCCPYLFVNKLISPT----------PSTLDVKNGGSHE-NSSSVDLHFMKKIPTGAEASNVLVGELDFLERPIVAFVRLSPAVLLTGLTEVPIPTRFLFILLGPVGKAQQYHEIGRSMATIMTDEIFHDVAYKAKDRGDLLAGIDEFLDQVTVLPPGEWDPSIRIEPPKNVPSQEKRKMPGVPNGN----------------------------VCHVEPEPEPEHSGPELQRTGMIFGGLVADIKRKAPFYLSDYRDALSLQCVASFLFLYCACMSPVITFGGLLGEATEGRISAIESLFGASMTGIAYSLFAGQPLTILGSTGPVLVFEKILFKFCKEYGLSYLSLRACIGLWTAFLCIFLVATDASSLVCYITRFTEEAFASLICIIFIYEAIEKLIHLGETYPVNMHSQLDKLTLYYCKCAAPASPTNDTLL--YWRENNI---------------------TITEAEWANFTVSE-----------CNKMHGEFVGPACGHHGPYTPDVLFWSCILFFTTFALSSVLKTFKTSRYFPTKVRSMVSDFAVFLTILTMVVLDYVIGVPSPKLQVPNEFKPT--RDDRGWLVNPIGPNPWWTVFPTIIPALLCTILIFMDQQITAVIINRKEHKLKKGCGYHLDLLVVGLMLGICSIMGLPWFVAATVLSITHVNSLKLESECSAPGEQPKFLGIREQRVTGLMIFVLMGCSVFMTTVLKFIPMPVLYGVFLYMGVSSLRGIQFFDRLLLFAMPAKHQPDFSYLRHVPLRKVHLFTIIQLTCLVLLWVIKASPA-AIVFPMMVLALVFVRKVMDFCFSDRELSWLDDLMPESKKKKLDDDCLSLSSMTPLLYFQLPLETRKLLSSPGKNNNSRGDPSEINISDEMPKTTVWKALS 1003          
BLAST of slc4a-1 vs. Ensembl Mouse
Match: Slc4a10 (solute carrier family 4, sodium bicarbonate cotransporter-like, member 10 [Source:MGI Symbol;Acc:MGI:2150150])

HSP 1 Score: 945.651 bits (2443), Expect = 0.000e+0
Identity = 546/1160 (47.07%), Postives = 746/1160 (64.31%), Query Frame = 2
Query:  125 DEPILDRG----FQFTHYHPSEDEIEDHRSQRALYIGVHMPPDXXXXXXXXXXXXXXXXXXXXXDKKDYLTEIAEDDTEKATDPSQHVMFLLG-EDEDEE--THNLFCEMDELRLDDEGEPEWKETARWIKFEEDVEEGGERWSKPHVASLSLYSLFEVRNCITSAVNMFNVEANNFETIIEIILNKIVSEKKISPDQREKVKEMLQRKHVHLHERRHKSNAKGSQLPLIRSLADIGKKYSS-KEVDKVQLQ-----------RRNSDYPTKFTRFDANXXXXXXXXXXXXXYVDKNRIDVDQCGSDNLASQKFDLHFFKKIPLGAETSNIMVGETDFLNQMVVVFIRLKEAVILGELTEVPVPTRFVFVMLGPQGSAVKNHEIGRSMATLMSDDVFHDVAYKARNLDDLLAGIDEFLSNCTVLPPAEWDPSIRIEPPKSGPIA--RKVPSMPNGAQALLTASGDGRXXXXXXXXXXXXXXASVVNKLQPVEEESHADPTLRRTGRLFGGLIEDVKRKAPFYLSDFKDAIHVQCFASFFFLYFACLTPIITFGGLLVQATGGYLGAIESILSGTIVGVVYSLFSGQPLTIMGSTGPVLVFESIVYNICERMRWDYLPFRLWIGVWIAAYLFLMVAFDLSALVRYITRFTEESFAALIALIFMVEAFKKLFLIVDYYPIDTRWNIDMIKNRTCECFPRNATAMDAFFQKNNKPSNVYMPPMLYPVPLNSSVIDIVNNIDWQNISNYHFTWDYKKYRLICTKWGGIWTGSGCGNY--FIPDVFFFSCLLFIGTFVLSYGLKMMRNAQFFPNWVRSLISDFAVMIAISSMTLLDWSLGFHTPKLNVPAKFEPTLGYKMRGWVIPALGKNPWWTIIIAMGPALLAVILIFMDQQITAVIVNRKENKLKKGSGYHXXXXXXXXXXXXXXXXGIPWFVAATVLSINHVMSLKKESENTAPGERPVFLGCREQRVTGTIIFLVIGLSVFLTPLLKRIPMAVLYGVFLFMGVASLKGVQLMQRISLFFMPAKYQPDYIFLRYVPLRRVHXXXXXXXXXXXXXXXXXXXNVMSICFPIMVLALCFVRKGLEYLFTYNELKWLDDIMPNHKKPPQDDNENDIEKCGSTELIKMTETNLEFNSSTNKVIRSNDSGINISEEMGKTAIWKQL 3535
            +E ++DRG       TH+     E ED    R L+IGVH+P     + + +R R      + +  ++D   E   +     T PSQ V F+LG ED+DEE   H+LF E+DE+   +  + EW+ETARW+KFEEDVE+GGERWSKP+VA+LSL+SLFE+R+CI +   + ++ AN  E I +++L++ VS  +++ D R +V E L ++H H ++++       +++P++RS ADIGKK S    +DK   Q              +D   + +  D +       K  +S    K R+D    G  +   ++ DLHF KKIP GAE SNI+VGE +FL++ VV F+RL  AV+L  L EVP+P+RF+F++LGP G   + HEIGRS+ATLM+D+VFHDVAYKA++ +DL++GIDEFL   TVLPP EWDPSIRIEPPK+ P    RK+P++PNG  A   A   G                             H+ P L+RTGR+FGGLI D+KRKAPF+ SDF+DA  +QC ASF FLY AC++P+ITFGGLL +AT G + AIES+   ++ G+ YSLF GQPLTI+GSTGPVLVFE I++  C+     YL  R  IG+W A    ++VA D S+LV YITRFTEE+FA+LI +IF+ EA +KLF + + YPI+   +++++   +C C   ++ + D    K  + SN+             S  DI+    W N++              C    G + G  CG+   ++PDV F+S +LF  T  +S  LK  + +++FP  VRS++SDFAV + I  M L+D+++G  +PKL VP+ F+PT     RGW +  LG NPWWTII A+ PALL  ILIFMDQQITAVI+NRKE+KLKKG GYHLDLL+VA+++ V SI+G+PWFVAATVLSI HV SLK ESE +APGE+P FLG REQRVTG +IF+++G SVF+T +LK IPM VLYGVFL+MG +SLKG+QL  RI LF+MPAK+QPD+I+LR+VPLR+VHLFT+IQ+  L LLW+IK     +I FP+MVLAL FVRK +++LFT  EL WLDD+MP  KK   +D E + E+   + L    E  ++     +   R + S INIS+EM KTA+W  L
Sbjct:   20 EEAVVDRGGTRSILKTHF-----EKEDLEGHRTLFIGVHVP--LGGRKSHRRHRHRGHKHRKRDRERDSGLEDGRESPSFDT-PSQRVQFILGTEDDDEEHLPHDLFTELDEICWREGEDAEWRETARWLKFEEDVEDGGERWSKPYVATLSLHSLFELRSCILNGTVLLDMHANTIEEIADMVLDQQVSSGQLNEDVRHRVHEALMKQHHHQNQKK-----LANRIPIVRSFADIGKKQSEPNSMDKNAGQVVSPQSAPACAENKNDVSRENSTVDFSKGLGGQQKGHTSPCGMKQRLDK---GPPHQQEREVDLHFMKKIPPGAEASNILVGELEFLDRTVVAFVRLSPAVLLQGLAEVPIPSRFLFILLGPLGKGQQYHEIGRSIATLMTDEVFHDVAYKAKDRNDLVSGIDEFLDQVTVLPPGEWDPSIRIEPPKNVPSQEKRKIPAVPNGTAAHGEAEPHG----------------------------GHSGPELQRTGRIFGGLILDIKRKAPFFWSDFRDAFSLQCLASFLFLYCACMSPVITFGGLLGEATEGRISAIESLFGASMTGIAYSLFGGQPLTILGSTGPVLVFEKILFKFCKEYGLSYLSLRASIGLWTATLCIILVATDASSLVCYITRFTEEAFASLICIIFIYEALEKLFELSETYPINMHNDLELLTQYSCNCMEPHSPSNDTL--KEWRESNL-------------SASDII----WGNLTVSE-----------CRSLHGEYVGRACGHGHPYVPDVLFWSVILFFSTVTMSATLKQFKTSRYFPTKVRSIVSDFAVFLTILCMVLIDYAIGIPSPKLQVPSVFKPT--RDDRGWFVTPLGPNPWWTIIAAIIPALLCTILIFMDQQITAVIINRKEHKLKKGCGYHLDLLMVAVMLGVCSIMGLPWFVAATVLSITHVNSLKLESECSAPGEQPKFLGIREQRVTGLMIFILMGSSVFMTSILKFIPMPVLYGVFLYMGASSLKGIQLFDRIKLFWMPAKHQPDFIYLRHVPLRKVHLFTVIQMSCLGLLWIIKVSRA-AIVFPMMVLALVFVRKLMDFLFTKRELSWLDDLMPESKKKKLEDAEKEEEQ---SMLAMEDEGTVQLPLEGH--YRDDPSVINISDEMSKTAMWGNL 1097          
BLAST of slc4a-1 vs. Ensembl Mouse
Match: Slc4a10 (solute carrier family 4, sodium bicarbonate cotransporter-like, member 10 [Source:MGI Symbol;Acc:MGI:2150150])

HSP 1 Score: 945.266 bits (2442), Expect = 0.000e+0
Identity = 545/1148 (47.47%), Postives = 742/1148 (64.63%), Query Frame = 2
Query:  125 DEPILDRG----FQFTHYHPSEDEIEDHRSQRALYIGVHMPPDXXXXXXXXXXXXXXXXXXXXXDKKDYLTEIAEDDTEKATDPSQHVMFLLG-EDEDEE--THNLFCEMDELRLDDEGEPEWKETARWIKFEEDVEEGGERWSKPHVASLSLYSLFEVRNCITSAVNMFNVEANNFETIIEIILNKIVSEKKISPDQREKVKEMLQRKHVHLHERRHKSNAKGSQLPLIRSLADIGKKYSSKEVDKVQLQRRNSDYPTKFTRFDANXXXXXXXXXXXXXYVDKNRIDVDQCGSDNLASQKFDLHFFKKIPLGAETSNIMVGETDFLNQMVVVFIRLKEAVILGELTEVPVPTRFVFVMLGPQGSAVKNHEIGRSMATLMSDDVFHDVAYKARNLDDLLAGIDEFLSNCTVLPPAEWDPSIRIEPPKSGPIA--RKVPSMPNGAQALLTASGDGRXXXXXXXXXXXXXXASVVNKLQPVEEESHADPTLRRTGRLFGGLIEDVKRKAPFYLSDFKDAIHVQCFASFFFLYFACLTPIITFGGLLVQATGGYLGAIESILSGTIVGVVYSLFSGQPLTIMGSTGPVLVFESIVYNICERMRWDYLPFRLWIGVWIAAYLFLMVAFDLSALVRYITRFTEESFAALIALIFMVEAFKKLFLIVDYYPIDTRWNIDMIKNRTCECFPRNATAMDAFFQKNNKPSNVYMPPMLYPVPLNSSVIDIVNNIDWQNISNYHFTWDYKKYRLICTKWGGIWTGSGCGNY--FIPDVFFFSCLLFIGTFVLSYGLKMMRNAQFFPNWVRSLISDFAVMIAISSMTLLDWSLGFHTPKLNVPAKFEPTLGYKMRGWVIPALGKNPWWTIIIAMGPALLAVILIFMDQQITAVIVNRKENKLKKGSGYHXXXXXXXXXXXXXXXXGIPWFVAATVLSINHVMSLKKESENTAPGERPVFLGCREQRVTGTIIFLVIGLSVFLTPLLKRIPMAVLYGVFLFMGVASLKGVQLMQRISLFFMPAKYQPDYIFLRYVPLRRVHXXXXXXXXXXXXXXXXXXXNVMSICFPIMVLALCFVRKGLEYLFTYNELKWLDDIMPNHKKPPQDDNENDIEKCGSTELIKMTETNLEFNSSTNKVIRSNDSGINISEEMGKTAIWKQL 3535
            +E ++DRG       TH+     E ED    R L+IGVH+P     + + +R R      + +  ++D   E   +     T PSQ V F+LG ED+DEE   H+LF E+DE+   +  + EW+ETARW+KFEEDVE+GGERWSKP+VA+LSL+SLFE+R+CI +   + ++ AN  E I +++L++ VS  +++ D R +V E L ++H H ++++       +++P++RS ADIGKK S            NS         D N+ Q    +S+ +   +KN +  +    D     K DLHF KKIP GAE SNI+VGE +FL++ VV F+RL  AV+L  L EVP+P+RF+F++LGP G   + HEIGRS+ATLM+D+VFHDVAYKA++ +DL++GIDEFL   TVLPP EWDPSIRIEPPK+ P    RK+P++PNG  A   A   G                             H+ P L+RTGR+FGGLI D+KRKAPF+ SDF+DA  +QC ASF FLY AC++P+ITFGGLL +AT G + AIES+   ++ G+ YSLF GQPLTI+GSTGPVLVFE I++  C+     YL  R  IG+W A    ++VA D S+LV YITRFTEE+FA+LI +IF+ EA +KLF + + YPI+   +++++   +C C   ++ + D    K  + SN+             S  DI+    W N++              C    G + G  CG+   ++PDV F+S +LF  T  +S  LK  + +++FP  VRS++SDFAV + I  M L+D+++G  +PKL VP+ F+PT     RGW +  LG NPWWTII A+ PALL  ILIFMDQQITAVI+NRKE+KLKKG GYHLDLL+VA+++ V SI+G+PWFVAATVLSI HV SLK ESE +APGE+P FLG REQRVTG +IF+++G SVF+T +LK IPM VLYGVFL+MG +SLKG+QL  RI LF+MPAK+QPD+I+LR+VPLR+VHLFT+IQ+  L LLW+IK     +I FP+MVLAL FVRK +++LFT  EL WLDD+MP  KK   +D E + E+   + L    E  ++     +   R + S INIS+EM KTA+W  L
Sbjct:   20 EEAVVDRGGTRSILKTHF-----EKEDLEGHRTLFIGVHVP--LGGRKSHRRHRHRGHKHRKRDRERDSGLEDGRESPSFDT-PSQRVQFILGTEDDDEEHLPHDLFTELDEICWREGEDAEWRETARWLKFEEDVEDGGERWSKPYVATLSLHSLFELRSCILNGTVLLDMHANTIEEIADMVLDQQVSSGQLNEDVRHRVHEALMKQHHHQNQKK-----LANRIPIVRSFADIGKKQSEP----------NS--------MDKNAGQVVSPQSAPACAENKNDVSRENSTVD---FSKVDLHFMKKIPPGAEASNILVGELEFLDRTVVAFVRLSPAVLLQGLAEVPIPSRFLFILLGPLGKGQQYHEIGRSIATLMTDEVFHDVAYKAKDRNDLVSGIDEFLDQVTVLPPGEWDPSIRIEPPKNVPSQEKRKIPAVPNGTAAHGEAEPHG----------------------------GHSGPELQRTGRIFGGLILDIKRKAPFFWSDFRDAFSLQCLASFLFLYCACMSPVITFGGLLGEATEGRISAIESLFGASMTGIAYSLFGGQPLTILGSTGPVLVFEKILFKFCKEYGLSYLSLRASIGLWTATLCIILVATDASSLVCYITRFTEEAFASLICIIFIYEALEKLFELSETYPINMHNDLELLTQYSCNCMEPHSPSNDTL--KEWRESNL-------------SASDII----WGNLTVSE-----------CRSLHGEYVGRACGHGHPYVPDVLFWSVILFFSTVTMSATLKQFKTSRYFPTKVRSIVSDFAVFLTILCMVLIDYAIGIPSPKLQVPSVFKPT--RDDRGWFVTPLGPNPWWTIIAAIIPALLCTILIFMDQQITAVIINRKEHKLKKGCGYHLDLLMVAVMLGVCSIMGLPWFVAATVLSITHVNSLKLESECSAPGEQPKFLGIREQRVTGLMIFILMGSSVFMTSILKFIPMPVLYGVFLYMGASSLKGIQLFDRIKLFWMPAKHQPDFIYLRHVPLRKVHLFTVIQMSCLGLLWIIKVSRA-AIVFPMMVLALVFVRKLMDFLFTKRELSWLDDLMPESKKKKLEDAEKEEEQ---SMLAMEDEGTVQLPLEGH--YRDDPSVINISDEMSKTAMWGNL 1067          
BLAST of slc4a-1 vs. Ensembl Mouse
Match: Slc4a10 (solute carrier family 4, sodium bicarbonate cotransporter-like, member 10 [Source:MGI Symbol;Acc:MGI:2150150])

HSP 1 Score: 944.495 bits (2440), Expect = 0.000e+0
Identity = 543/1148 (47.30%), Postives = 740/1148 (64.46%), Query Frame = 2
Query:  125 DEPILDRG----FQFTHYHPSEDEIEDHRSQRALYIGVHMPPDXXXXXXXXXXXXXXXXXXXXXDKKDYLTEIAEDDTEKATDPSQHVMFLLG-EDEDEE--THNLFCEMDELRLDDEGEPEWKETARWIKFEEDVEEGGERWSKPHVASLSLYSLFEVRNCITSAVNMFNVEANNFETIIEIILNKIVSEKKISPDQREKVKEMLQRKHVHLHERRHKSNAKGSQLPLIRSLADIGKKYSSKEVDKVQLQRRNSDYPTKFTRFDANXXXXXXXXXXXXXYVDKNRIDVDQCGSDNLASQKFDLHFFKKIPLGAETSNIMVGETDFLNQMVVVFIRLKEAVILGELTEVPVPTRFVFVMLGPQGSAVKNHEIGRSMATLMSDDVFHDVAYKARNLDDLLAGIDEFLSNCTVLPPAEWDPSIRIEPPKSGPIA--RKVPSMPNGAQALLTASGDGRXXXXXXXXXXXXXXASVVNKLQPVEEESHADPTLRRTGRLFGGLIEDVKRKAPFYLSDFKDAIHVQCFASFFFLYFACLTPIITFGGLLVQATGGYLGAIESILSGTIVGVVYSLFSGQPLTIMGSTGPVLVFESIVYNICERMRWDYLPFRLWIGVWIAAYLFLMVAFDLSALVRYITRFTEESFAALIALIFMVEAFKKLFLIVDYYPIDTRWNIDMIKNRTCECFPRNATAMDAFFQKNNKPSNVYMPPMLYPVPLNSSVIDIVNNIDWQNISNYHFTWDYKKYRLICTKWGGIWTGSGCGNY--FIPDVFFFSCLLFIGTFVLSYGLKMMRNAQFFPNWVRSLISDFAVMIAISSMTLLDWSLGFHTPKLNVPAKFEPTLGYKMRGWVIPALGKNPWWTIIIAMGPALLAVILIFMDQQITAVIVNRKENKLKKGSGYHXXXXXXXXXXXXXXXXGIPWFVAATVLSINHVMSLKKESENTAPGERPVFLGCREQRVTGTIIFLVIGLSVFLTPLLKRIPMAVLYGVFLFMGVASLKGVQLMQRISLFFMPAKYQPDYIFLRYVPLRRVHXXXXXXXXXXXXXXXXXXXNVMSICFPIMVLALCFVRKGLEYLFTYNELKWLDDIMPNHKKPPQDDNENDIEKCGSTELIKMTETNLEFNSSTNKVIRSNDSGINISEEMGKTAIWKQL 3535
            +E ++DRG       TH+     E ED    R L+IGVH+P     + + +R R      + +  ++D   E   +     T PSQ V F+LG ED+DEE   H+LF E+DE+   +  + EW+ETARW+KFEEDVE+GGERWSKP+VA+LSL+SLFE+R+CI +   + ++ AN  E I +++L++ VS  +++ D R +V E L ++H H ++++       +++P++RS ADIGKK S                       D N+ Q    +S+ +   +KN +  +    D     K DLHF KKIP GAE SNI+VGE +FL++ VV F+RL  AV+L  L EVP+P+RF+F++LGP G   + HEIGRS+ATLM+D+VFHDVAYKA++ +DL++GIDEFL   TVLPP EWDPSIRIEPPK+ P    RK+P++PNG  A   A   G                             H+ P L+RTGR+FGGLI D+KRKAPF+ SDF+DA  +QC ASF FLY AC++P+ITFGGLL +AT G + AIES+   ++ G+ YSLF GQPLTI+GSTGPVLVFE I++  C+     YL  R  IG+W A    ++VA D S+LV YITRFTEE+FA+LI +IF+ EA +KLF + + YPI+   +++++   +C C   ++ + D    K  + SN+             S  DI+    W N++              C    G + G  CG+   ++PDV F+S +LF  T  +S  LK  + +++FP  VRS++SDFAV + I  M L+D+++G  +PKL VP+ F+PT     RGW +  LG NPWWTII A+ PALL  ILIFMDQQITAVI+NRKE+KLKKG GYHLDLL+VA+++ V SI+G+PWFVAATVLSI HV SLK ESE +APGE+P FLG REQRVTG +IF+++G SVF+T +LK IPM VLYGVFL+MG +SLKG+QL  RI LF+MPAK+QPD+I+LR+VPLR+VHLFT+IQ+  L LLW+IK     +I FP+MVLAL FVRK +++LFT  EL WLDD+MP  KK   +D E + E+   + L    E  ++     +   R + S INIS+EM KTA+W  L
Sbjct:   20 EEAVVDRGGTRSILKTHF-----EKEDLEGHRTLFIGVHVP--LGGRKSHRRHRHRGHKHRKRDRERDSGLEDGRESPSFDT-PSQRVQFILGTEDDDEEHLPHDLFTELDEICWREGEDAEWRETARWLKFEEDVEDGGERWSKPYVATLSLHSLFELRSCILNGTVLLDMHANTIEEIADMVLDQQVSSGQLNEDVRHRVHEALMKQHHHQNQKK-----LANRIPIVRSFADIGKKQSEP------------------NSMDKNAGQVVSPQSAPACAENKNDVSRENSTVD---FSKVDLHFMKKIPPGAEASNILVGELEFLDRTVVAFVRLSPAVLLQGLAEVPIPSRFLFILLGPLGKGQQYHEIGRSIATLMTDEVFHDVAYKAKDRNDLVSGIDEFLDQVTVLPPGEWDPSIRIEPPKNVPSQEKRKIPAVPNGTAAHGEAEPHG----------------------------GHSGPELQRTGRIFGGLILDIKRKAPFFWSDFRDAFSLQCLASFLFLYCACMSPVITFGGLLGEATEGRISAIESLFGASMTGIAYSLFGGQPLTILGSTGPVLVFEKILFKFCKEYGLSYLSLRASIGLWTATLCIILVATDASSLVCYITRFTEEAFASLICIIFIYEALEKLFELSETYPINMHNDLELLTQYSCNCMEPHSPSNDTL--KEWRESNL-------------SASDII----WGNLTVSE-----------CRSLHGEYVGRACGHGHPYVPDVLFWSVILFFSTVTMSATLKQFKTSRYFPTKVRSIVSDFAVFLTILCMVLIDYAIGIPSPKLQVPSVFKPT--RDDRGWFVTPLGPNPWWTIIAAIIPALLCTILIFMDQQITAVIINRKEHKLKKGCGYHLDLLMVAVMLGVCSIMGLPWFVAATVLSITHVNSLKLESECSAPGEQPKFLGIREQRVTGLMIFILMGSSVFMTSILKFIPMPVLYGVFLYMGASSLKGIQLFDRIKLFWMPAKHQPDFIYLRHVPLRKVHLFTVIQMSCLGLLWIIKVSRA-AIVFPMMVLALVFVRKLMDFLFTKRELSWLDDLMPESKKKKLEDAEKEEEQ---SMLAMEDEGTVQLPLEGH--YRDDPSVINISDEMSKTAMWGNL 1067          
BLAST of slc4a-1 vs. Ensembl Mouse
Match: Slc4a7 (solute carrier family 4, sodium bicarbonate cotransporter, member 7 [Source:MGI Symbol;Acc:MGI:2443878])

HSP 1 Score: 929.472 bits (2401), Expect = 0.000e+0
Identity = 542/1159 (46.76%), Postives = 730/1159 (62.99%), Query Frame = 2
Query:  182 EIEDHRSQRALYIGVHMPPDXXXXXXXXXXXXXXXXXXXXXDKKDYLTEIAEDDTEKAT--DPSQHVMFLLG-EDEDEE--THNLFCEMDELRLDDEGEPEWKETARWIKFEEDVEEGGERWSKPHVASLSLYSLFEVRNCITSAVNMFNVEANNFETIIEIILNKIVSEKKISPDQREKVKEMLQRKHVHLHERRHKSNAKGSQLPLIRSLADIGKKYSSKEVDKVQLQRRNS--DYPTKFTRFDANXXXXXXXXXXXXXYVDKNRIDVDQ--------CGSDNLASQK--FDLHFFKKIPLGAETSNIMVGETDFLNQMVVVFIRLKEAVILGELTEVPVPTRFVFVMLGPQGSAVKNHEIGRSMATLMSDDVFHDVAYKARNLDDLLAGIDEFLSNCTVLPPAEWDPSIRIEPPKSGPIA--RKVPSMPNGAQALLTASGDGRXXXXXXXXXXXXXXASVVNKLQPVEEESHADPTLRRTGRLFGGLIEDVKRKAPFYLSDFKDAIHVQCFASFFFLYFACLTPIITFGGLLVQATGGYLGAIESILSGTIVGVVYSLFSGQPLTIMGSTGPVLVFESIVYNICERMRWDYLPFRLWIGVWIAAYLFLMVAFDLSALVRYITRFTEESFAALIALIFMVEAFKKLFLIVDYYPIDTRWNIDMIKNRTCECFPRNATAMDAFFQKNNKPSNVYMPPMLYPVPLNSSVIDIVNNIDWQNISNYHFTWDYKKYRLICTKWGGIWTGSGCGNY--FIPDVFFFSCLLFIGTFVLSYGLKMMRNAQFFPNWVRSLISDFAVMIAISSMTLLDWSLGFHTPKLNVPAKFEPTLGYKMRGWVIPALGKNPWWTIIIAMGPALLAVILIFMDQQITAVIVNRKENKLKKGSGYHXXXXXXXXXXXXXXXXGIPWFVAATVLSINHVMSLKKESENTAPGERPVFLGCREQRVTGTIIFLVIGLSVFLTPLLKRIPMAVLYGVFLFMGVASLKGVQLMQRISLFFMPAKYQPDYIFLRYVPLRRVHXXXXXXXXXXXXXXXXXXXNVMSICFPIMVLALCFVRKGLEYLFTYNELKWLDDIMPNH----------------KKPPQDDNENDIEKCGSTELIKMTETNLEFNSSTNKVIRSNDSGINISEEMGKTAIWKQLSGGT 3547
            E E+  S RA+Y+GVH+P  +  +   + R      ++ +    D      ED  E  +   PSQ V F+LG ED+DEE   H+LF EMDEL   D  E EWKETARW+KFEEDVE+GG+RWSKP+VA+LSL+SLFE+R+CI +   M ++ A+  + I +++L+ +++  ++    RE V+E L ++H H +E+R  S     ++PL+RS ADIGKK+S        L  RN     P        NS    +  + S    + + +D  +        CG+  +  +K   D++F +KIP GAE SN++VGE DFL + ++ F+RL  AV+L  LTEVPVPTRF+F++LGP G A + HEIGRS+ATLM+D++FHDVAYKA++ +DLL+GIDEFL   TVLPP EWDPSIRIEPPKS P    RK+P  PNG+ A+   S D                        P E++ HA P L+RTGRLFGGLI D+KRKAPF+LSDFKDA+ +QC AS  FLY AC++P+ITFGGLL +AT G + AIES+   ++ G+ YSLF+GQPLTI+GSTGPVLVFE I++  C      YL  R  IG+W +    ++VA D S+LV YITRFTEE+FAALI +IF+ EA +KLF + + Y  +   N+D + + TC C                +PSN          P N +    +     +NI+ Y  +W        C  + G++ GS CG +  ++PDV F+  +LF  TF LS  LK  +  ++FP  VRS ISDFAV + I  M  +D+ +G  +PKL+VP KFEPT     RGW+I  LG NPWWT++IA  PALL  ILIFMDQQITAVI+NRKE+KLKKG+GYHLDLL+V +++ V SI+G+PWFVAATVLSI+HV SLK ESE +APGE+P FLG REQRVTG +IF+++GLSVF+T +LK IPM VLYGVFL+MGV+SLKG+Q   RI LF MPAK+QPD I+LRYVPL +VH    +  +  ++L  +   +  ++ FP+MVLAL FVRK ++  FT  EL WLDD+MP                  ++  QDD +          L+++    L+++         + S +NIS+EM KTA WK LS  T
Sbjct:   33 EKEELESHRAVYVGVHVPFSKESRRRHKHRGHKHHHRRRKDKDSD-----KEDGRESPSYDTPSQRVQFILGTEDDDEEHIPHDLFTEMDELCYRDGEEYEWKETARWLKFEEDVEDGGDRWSKPYVATLSLHSLFELRSCILNGTVMLDMRASTLDEIADMVLDNMIASGQLDDSIRENVREALLKRHHHQNEKRFTS-----RIPLVRSFADIGKKHSDP-----HLLERNGILASPQSAPGNLDNSKSGEMKGNGSGGSRENSTVDFSKESASWHCSCGTLGVGLKKPAVDMNFMRKIPTGAEASNVLVGEVDFLERPIIAFVRLAPAVLLSGLTEVPVPTRFLFLLLGPAGKAPQYHEIGRSIATLMTDEIFHDVAYKAKDRNDLLSGIDEFLDQVTVLPPGEWDPSIRIEPPKSVPSQEKRKIPVFPNGSAAM---SVD-----------------------PPKEDDHHAGPELQRTGRLFGGLILDIKRKAPFFLSDFKDALSLQCLASILFLYCACMSPVITFGGLLGEATEGRISAIESLFGASLTGIAYSLFAGQPLTILGSTGPVLVFEKILFKFCRDYHLSYLSLRTSIGLWTSFLCIVLVATDASSLVCYITRFTEEAFAALICIIFIYEALEKLFHLGEIYAFNMHNNLDELTSYTCVC---------------AEPSN----------PSNET----LELWKRKNITAYSVSWGNLTVSE-CKTFHGMFVGSACGPHGPYVPDVLFWCVVLFFTTFFLSSFLKQFKTKRYFPTKVRSTISDFAVFLTIVIMVAIDYLVGIPSPKLHVPEKFEPT--DPSRGWIISPLGDNPWWTLLIAAVPALLCTILIFMDQQITAVIINRKEHKLKKGAGYHLDLLMVGVMLGVCSIMGLPWFVAATVLSISHVNSLKVESECSAPGEQPKFLGIREQRVTGLMIFILMGLSVFMTSVLKFIPMPVLYGVFLYMGVSSLKGIQFFDRIKLFGMPAKHQPDLIYLRYVPLWKVH-VFTVVQLTCLVLLWVIKASAAAVVFPMMVLALVFVRKLMDLCFTKRELSWLDDLMPESKKKKEDDKKKKEKEEAERMLQDDEDTVHLPFERGSLLQIPVKTLKYS--------IDPSVVNISDEMAKTAQWKALSMNT 1109          
BLAST of slc4a-1 vs. Ensembl Mouse
Match: Slc4a7 (solute carrier family 4, sodium bicarbonate cotransporter, member 7 [Source:MGI Symbol;Acc:MGI:2443878])

HSP 1 Score: 929.472 bits (2401), Expect = 0.000e+0
Identity = 542/1159 (46.76%), Postives = 730/1159 (62.99%), Query Frame = 2
Query:  182 EIEDHRSQRALYIGVHMPPDXXXXXXXXXXXXXXXXXXXXXDKKDYLTEIAEDDTEKAT--DPSQHVMFLLG-EDEDEE--THNLFCEMDELRLDDEGEPEWKETARWIKFEEDVEEGGERWSKPHVASLSLYSLFEVRNCITSAVNMFNVEANNFETIIEIILNKIVSEKKISPDQREKVKEMLQRKHVHLHERRHKSNAKGSQLPLIRSLADIGKKYSSKEVDKVQLQRRNS--DYPTKFTRFDANXXXXXXXXXXXXXYVDKNRIDVDQ--------CGSDNLASQK--FDLHFFKKIPLGAETSNIMVGETDFLNQMVVVFIRLKEAVILGELTEVPVPTRFVFVMLGPQGSAVKNHEIGRSMATLMSDDVFHDVAYKARNLDDLLAGIDEFLSNCTVLPPAEWDPSIRIEPPKSGPIA--RKVPSMPNGAQALLTASGDGRXXXXXXXXXXXXXXASVVNKLQPVEEESHADPTLRRTGRLFGGLIEDVKRKAPFYLSDFKDAIHVQCFASFFFLYFACLTPIITFGGLLVQATGGYLGAIESILSGTIVGVVYSLFSGQPLTIMGSTGPVLVFESIVYNICERMRWDYLPFRLWIGVWIAAYLFLMVAFDLSALVRYITRFTEESFAALIALIFMVEAFKKLFLIVDYYPIDTRWNIDMIKNRTCECFPRNATAMDAFFQKNNKPSNVYMPPMLYPVPLNSSVIDIVNNIDWQNISNYHFTWDYKKYRLICTKWGGIWTGSGCGNY--FIPDVFFFSCLLFIGTFVLSYGLKMMRNAQFFPNWVRSLISDFAVMIAISSMTLLDWSLGFHTPKLNVPAKFEPTLGYKMRGWVIPALGKNPWWTIIIAMGPALLAVILIFMDQQITAVIVNRKENKLKKGSGYHXXXXXXXXXXXXXXXXGIPWFVAATVLSINHVMSLKKESENTAPGERPVFLGCREQRVTGTIIFLVIGLSVFLTPLLKRIPMAVLYGVFLFMGVASLKGVQLMQRISLFFMPAKYQPDYIFLRYVPLRRVHXXXXXXXXXXXXXXXXXXXNVMSICFPIMVLALCFVRKGLEYLFTYNELKWLDDIMPNH----------------KKPPQDDNENDIEKCGSTELIKMTETNLEFNSSTNKVIRSNDSGINISEEMGKTAIWKQLSGGT 3547
            E E+  S RA+Y+GVH+P  +  +   + R      ++ +    D      ED  E  +   PSQ V F+LG ED+DEE   H+LF EMDEL   D  E EWKETARW+KFEEDVE+GG+RWSKP+VA+LSL+SLFE+R+CI +   M ++ A+  + I +++L+ +++  ++    RE V+E L ++H H +E+R  S     ++PL+RS ADIGKK+S        L  RN     P        NS    +  + S    + + +D  +        CG+  +  +K   D++F +KIP GAE SN++VGE DFL + ++ F+RL  AV+L  LTEVPVPTRF+F++LGP G A + HEIGRS+ATLM+D++FHDVAYKA++ +DLL+GIDEFL   TVLPP EWDPSIRIEPPKS P    RK+P  PNG+ A+   S D                        P E++ HA P L+RTGRLFGGLI D+KRKAPF+LSDFKDA+ +QC AS  FLY AC++P+ITFGGLL +AT G + AIES+   ++ G+ YSLF+GQPLTI+GSTGPVLVFE I++  C      YL  R  IG+W +    ++VA D S+LV YITRFTEE+FAALI +IF+ EA +KLF + + Y  +   N+D + + TC C                +PSN          P N +    +     +NI+ Y  +W        C  + G++ GS CG +  ++PDV F+  +LF  TF LS  LK  +  ++FP  VRS ISDFAV + I  M  +D+ +G  +PKL+VP KFEPT     RGW+I  LG NPWWT++IA  PALL  ILIFMDQQITAVI+NRKE+KLKKG+GYHLDLL+V +++ V SI+G+PWFVAATVLSI+HV SLK ESE +APGE+P FLG REQRVTG +IF+++GLSVF+T +LK IPM VLYGVFL+MGV+SLKG+Q   RI LF MPAK+QPD I+LRYVPL +VH    +  +  ++L  +   +  ++ FP+MVLAL FVRK ++  FT  EL WLDD+MP                  ++  QDD +          L+++    L+++         + S +NIS+EM KTA WK LS  T
Sbjct:   38 EKEELESHRAVYVGVHVPFSKESRRRHKHRGHKHHHRRRKDKDSD-----KEDGRESPSYDTPSQRVQFILGTEDDDEEHIPHDLFTEMDELCYRDGEEYEWKETARWLKFEEDVEDGGDRWSKPYVATLSLHSLFELRSCILNGTVMLDMRASTLDEIADMVLDNMIASGQLDDSIRENVREALLKRHHHQNEKRFTS-----RIPLVRSFADIGKKHSDP-----HLLERNGILASPQSAPGNLDNSKSGEMKGNGSGGSRENSTVDFSKESASWHCSCGTLGVGLKKPAVDMNFMRKIPTGAEASNVLVGEVDFLERPIIAFVRLAPAVLLSGLTEVPVPTRFLFLLLGPAGKAPQYHEIGRSIATLMTDEIFHDVAYKAKDRNDLLSGIDEFLDQVTVLPPGEWDPSIRIEPPKSVPSQEKRKIPVFPNGSAAM---SVD-----------------------PPKEDDHHAGPELQRTGRLFGGLILDIKRKAPFFLSDFKDALSLQCLASILFLYCACMSPVITFGGLLGEATEGRISAIESLFGASLTGIAYSLFAGQPLTILGSTGPVLVFEKILFKFCRDYHLSYLSLRTSIGLWTSFLCIVLVATDASSLVCYITRFTEEAFAALICIIFIYEALEKLFHLGEIYAFNMHNNLDELTSYTCVC---------------AEPSN----------PSNET----LELWKRKNITAYSVSWGNLTVSE-CKTFHGMFVGSACGPHGPYVPDVLFWCVVLFFTTFFLSSFLKQFKTKRYFPTKVRSTISDFAVFLTIVIMVAIDYLVGIPSPKLHVPEKFEPT--DPSRGWIISPLGDNPWWTLLIAAVPALLCTILIFMDQQITAVIINRKEHKLKKGAGYHLDLLMVGVMLGVCSIMGLPWFVAATVLSISHVNSLKVESECSAPGEQPKFLGIREQRVTGLMIFILMGLSVFMTSVLKFIPMPVLYGVFLYMGVSSLKGIQFFDRIKLFGMPAKHQPDLIYLRYVPLWKVH-VFTVVQLTCLVLLWVIKASAAAVVFPMMVLALVFVRKLMDLCFTKRELSWLDDLMPESKKKKEDDKKKKEKEEAERMLQDDEDTVHLPFERGSLLQIPVKTLKYS--------IDPSVVNISDEMAKTAQWKALSMNT 1114          
BLAST of slc4a-1 vs. UniProt/SwissProt
Match: sp|Q5DTL9|S4A10_MOUSE (Sodium-driven chloride bicarbonate exchanger OS=Mus musculus OX=10090 GN=Slc4a10 PE=1 SV=2)

HSP 1 Score: 945.651 bits (2443), Expect = 0.000e+0
Identity = 546/1160 (47.07%), Postives = 746/1160 (64.31%), Query Frame = 2
Query:  125 DEPILDRG----FQFTHYHPSEDEIEDHRSQRALYIGVHMPPDXXXXXXXXXXXXXXXXXXXXXDKKDYLTEIAEDDTEKATDPSQHVMFLLG-EDEDEE--THNLFCEMDELRLDDEGEPEWKETARWIKFEEDVEEGGERWSKPHVASLSLYSLFEVRNCITSAVNMFNVEANNFETIIEIILNKIVSEKKISPDQREKVKEMLQRKHVHLHERRHKSNAKGSQLPLIRSLADIGKKYSS-KEVDKVQLQ-----------RRNSDYPTKFTRFDANXXXXXXXXXXXXXYVDKNRIDVDQCGSDNLASQKFDLHFFKKIPLGAETSNIMVGETDFLNQMVVVFIRLKEAVILGELTEVPVPTRFVFVMLGPQGSAVKNHEIGRSMATLMSDDVFHDVAYKARNLDDLLAGIDEFLSNCTVLPPAEWDPSIRIEPPKSGPIA--RKVPSMPNGAQALLTASGDGRXXXXXXXXXXXXXXASVVNKLQPVEEESHADPTLRRTGRLFGGLIEDVKRKAPFYLSDFKDAIHVQCFASFFFLYFACLTPIITFGGLLVQATGGYLGAIESILSGTIVGVVYSLFSGQPLTIMGSTGPVLVFESIVYNICERMRWDYLPFRLWIGVWIAAYLFLMVAFDLSALVRYITRFTEESFAALIALIFMVEAFKKLFLIVDYYPIDTRWNIDMIKNRTCECFPRNATAMDAFFQKNNKPSNVYMPPMLYPVPLNSSVIDIVNNIDWQNISNYHFTWDYKKYRLICTKWGGIWTGSGCGNY--FIPDVFFFSCLLFIGTFVLSYGLKMMRNAQFFPNWVRSLISDFAVMIAISSMTLLDWSLGFHTPKLNVPAKFEPTLGYKMRGWVIPALGKNPWWTIIIAMGPALLAVILIFMDQQITAVIVNRKENKLKKGSGYHXXXXXXXXXXXXXXXXGIPWFVAATVLSINHVMSLKKESENTAPGERPVFLGCREQRVTGTIIFLVIGLSVFLTPLLKRIPMAVLYGVFLFMGVASLKGVQLMQRISLFFMPAKYQPDYIFLRYVPLRRVHXXXXXXXXXXXXXXXXXXXNVMSICFPIMVLALCFVRKGLEYLFTYNELKWLDDIMPNHKKPPQDDNENDIEKCGSTELIKMTETNLEFNSSTNKVIRSNDSGINISEEMGKTAIWKQL 3535
            +E ++DRG       TH+     E ED    R L+IGVH+P     + + +R R      + +  ++D   E   +     T PSQ V F+LG ED+DEE   H+LF E+DE+   +  + EW+ETARW+KFEEDVE+GGERWSKP+VA+LSL+SLFE+R+CI +   + ++ AN  E I +++L++ VS  +++ D R +V E L ++H H ++++       +++P++RS ADIGKK S    +DK   Q              +D   + +  D +       K  +S    K R+D    G  +   ++ DLHF KKIP GAE SNI+VGE +FL++ VV F+RL  AV+L  L EVP+P+RF+F++LGP G   + HEIGRS+ATLM+D+VFHDVAYKA++ +DL++GIDEFL   TVLPP EWDPSIRIEPPK+ P    RK+P++PNG  A   A   G                             H+ P L+RTGR+FGGLI D+KRKAPF+ SDF+DA  +QC ASF FLY AC++P+ITFGGLL +AT G + AIES+   ++ G+ YSLF GQPLTI+GSTGPVLVFE I++  C+     YL  R  IG+W A    ++VA D S+LV YITRFTEE+FA+LI +IF+ EA +KLF + + YPI+   +++++   +C C   ++ + D    K  + SN+             S  DI+    W N++              C    G + G  CG+   ++PDV F+S +LF  T  +S  LK  + +++FP  VRS++SDFAV + I  M L+D+++G  +PKL VP+ F+PT     RGW +  LG NPWWTII A+ PALL  ILIFMDQQITAVI+NRKE+KLKKG GYHLDLL+VA+++ V SI+G+PWFVAATVLSI HV SLK ESE +APGE+P FLG REQRVTG +IF+++G SVF+T +LK IPM VLYGVFL+MG +SLKG+QL  RI LF+MPAK+QPD+I+LR+VPLR+VHLFT+IQ+  L LLW+IK     +I FP+MVLAL FVRK +++LFT  EL WLDD+MP  KK   +D E + E+   + L    E  ++     +   R + S INIS+EM KTA+W  L
Sbjct:   20 EEAVVDRGGTRSILKTHF-----EKEDLEGHRTLFIGVHVP--LGGRKSHRRHRHRGHKHRKRDRERDSGLEDGRESPSFDT-PSQRVQFILGTEDDDEEHLPHDLFTELDEICWREGEDAEWRETARWLKFEEDVEDGGERWSKPYVATLSLHSLFELRSCILNGTVLLDMHANTIEEIADMVLDQQVSSGQLNEDVRHRVHEALMKQHHHQNQKK-----LANRIPIVRSFADIGKKQSEPNSMDKNAGQVVSPQSAPACAENKNDVSRENSTVDFSKGLGGQQKGHTSPCGMKQRLDK---GPPHQQEREVDLHFMKKIPPGAEASNILVGELEFLDRTVVAFVRLSPAVLLQGLAEVPIPSRFLFILLGPLGKGQQYHEIGRSIATLMTDEVFHDVAYKAKDRNDLVSGIDEFLDQVTVLPPGEWDPSIRIEPPKNVPSQEKRKIPAVPNGTAAHGEAEPHG----------------------------GHSGPELQRTGRIFGGLILDIKRKAPFFWSDFRDAFSLQCLASFLFLYCACMSPVITFGGLLGEATEGRISAIESLFGASMTGIAYSLFGGQPLTILGSTGPVLVFEKILFKFCKEYGLSYLSLRASIGLWTATLCIILVATDASSLVCYITRFTEEAFASLICIIFIYEALEKLFELSETYPINMHNDLELLTQYSCNCMEPHSPSNDTL--KEWRESNL-------------SASDII----WGNLTVSE-----------CRSLHGEYVGRACGHGHPYVPDVLFWSVILFFSTVTMSATLKQFKTSRYFPTKVRSIVSDFAVFLTILCMVLIDYAIGIPSPKLQVPSVFKPT--RDDRGWFVTPLGPNPWWTIIAAIIPALLCTILIFMDQQITAVIINRKEHKLKKGCGYHLDLLMVAVMLGVCSIMGLPWFVAATVLSITHVNSLKLESECSAPGEQPKFLGIREQRVTGLMIFILMGSSVFMTSILKFIPMPVLYGVFLYMGASSLKGIQLFDRIKLFWMPAKHQPDFIYLRHVPLRKVHLFTVIQMSCLGLLWIIKVSRA-AIVFPMMVLALVFVRKLMDFLFTKRELSWLDDLMPESKKKKLEDAEKEEEQ---SMLAMEDEGTVQLPLEGH--YRDDPSVINISDEMSKTAMWGNL 1097          
BLAST of slc4a-1 vs. UniProt/SwissProt
Match: sp|Q80ZA5|S4A10_RAT (Sodium-driven chloride bicarbonate exchanger OS=Rattus norvegicus OX=10116 GN=Slc4a10 PE=1 SV=1)

HSP 1 Score: 944.88 bits (2441), Expect = 0.000e+0
Identity = 547/1159 (47.20%), Postives = 746/1159 (64.37%), Query Frame = 2
Query:  125 DEPILDRG----FQFTHYHPSEDEIEDHRSQRALYIGVHMPPDXXXXXXXXXXXXXXXXXXXXXDKKDYLTEIAEDDTEKATDPSQHVMFLLG-EDEDEE--THNLFCEMDELRLDDEGEPEWKETARWIKFEEDVEEGGERWSKPHVASLSLYSLFEVRNCITSAVNMFNVEANNFETIIEIILNKIVSEKKISPDQREKVKEMLQRKHVHLHERRHKSNAKGSQLPLIRSLADIGKKYSS-KEVDK----------VQLQRRNSDYPTKFTRFDANXXXXXXXXXXXXXYVDKNRIDVDQCGSDNLASQKFDLHFFKKIPLGAETSNIMVGETDFLNQMVVVFIRLKEAVILGELTEVPVPTRFVFVMLGPQGSAVKNHEIGRSMATLMSDDVFHDVAYKARNLDDLLAGIDEFLSNCTVLPPAEWDPSIRIEPPKSGPIA--RKVPSMPNGAQALLTASGDGRXXXXXXXXXXXXXXASVVNKLQPVEEESHADPTLRRTGRLFGGLIEDVKRKAPFYLSDFKDAIHVQCFASFFFLYFACLTPIITFGGLLVQATGGYLGAIESILSGTIVGVVYSLFSGQPLTIMGSTGPVLVFESIVYNICERMRWDYLPFRLWIGVWIAAYLFLMVAFDLSALVRYITRFTEESFAALIALIFMVEAFKKLFLIVDYYPIDTRWNIDMIKNRTCECFPRNATAMDAFFQKNNKPSNVYMPPMLYPVPLNSSVIDIVNNIDWQNISNYHFTWDYKKYRLICTKWGGIWTGSGCGNY--FIPDVFFFSCLLFIGTFVLSYGLKMMRNAQFFPNWVRSLISDFAVMIAISSMTLLDWSLGFHTPKLNVPAKFEPTLGYKMRGWVIPALGKNPWWTIIIAMGPALLAVILIFMDQQITAVIVNRKENKLKKGSGYHXXXXXXXXXXXXXXXXGIPWFVAATVLSINHVMSLKKESENTAPGERPVFLGCREQRVTGTIIFLVIGLSVFLTPLLKRIPMAVLYGVFLFMGVASLKGVQLMQRISLFFMPAKYQPDYIFLRYVPLRRVHXXXXXXXXXXXXXXXXXXXNVMSICFPIMVLALCFVRKGLEYLFTYNELKWLDDIMPNHKKPPQDDNENDIEKCGSTELIKMTETNLEFNSSTNKVIRSNDSGINISEEMGKTAIWKQL 3535
            +E ++DRG       TH+     E ED    R L+IGVH+P     + + +R R      + +  ++D   E   +     T PSQ V F+LG ED+DEE   H+LF E+DE+   +  + EW+ETARW+KFEEDVE+GGERWSKP+VA+LSL+SLFE+R+CI +   + ++ AN  E I +++L++ VS  +++ D R +V E L ++H H  +++  +     ++P++RS ADIGKK S    +DK                 +D   + +  D +       K  +S    K R+D    G  +   ++ DLHF KKIP GAE SNI+VGE +FL++ VV F+RL  AV+L  L EVP+P+RF+F++LGP G   + HEIGRS+ATLM+D+VFHDVAYKA++ +DL++GIDEFL   TVLPP EWDPSIRIEPPK+ P    RK PS+PNG     TA+  G                       P +   H+ P L+RTGR+FGGLI D+KRKAPF+ SDF+DA  +QC ASF FLY AC++P+ITFGGLL +AT G + AIES+   ++ G+ YSLF GQPLTI+GSTGPVLVFE I++  C+     YL  R  IG+W A    ++VA D S+LV YITRFTEE+FA+LI +IF+ EA +KLF + + YPI+   +++++   +C C   ++ + D    K  + SN+             S  DI+    W N++              C    G + G  CG+   ++PDV F+S +LF  T  +S  LK  + +++FP  VRS++SDFAV + I  M L+D+++G  +PKL VP+ F+PT     RGW +  LG NPWWTII A+ PALL  ILIFMDQQITAVI+NRKE+KLKKG GYHLDLL+VA+++ V SI+G+PWFVAATVLSI HV SLK ESE +APGE+P FLG REQRVTG +IF+++G SVF+T +LK IPM VLYGVFL+MG +SLKG+QL  RI LF+MPAK+QPD+I+LR+VPLR+VHLFT+IQ+  L LLW+IK     +I FP+MVLAL FVRK +++LFT  EL WLDD+MP  KK   +D E + E+   + L    E  ++     +   R + S INIS+EM KTA+W  L
Sbjct:   20 EEAVVDRGGTRSILKTHF-----EKEDLEGHRTLFIGVHVP--LGGRKSHRRHRHRGHKHRKRDRERDSGLEDGGESPSFDT-PSQRVQFILGTEDDDEEHIPHDLFTELDEICWREGEDAEWRETARWLKFEEDVEDGGERWSKPYVATLSLHSLFELRSCILNGTVLLDMHANTLEEIADMVLDQQVSSGQLNEDVRHRVHEALMKQHHHQSQKKLTN-----RIPIVRSFADIGKKQSEPNSMDKNGQVVSPQSAPACAENKNDVSRENSTVDFSKGLGGQQKGHTSPCGMKQRLDK---GPPHQQEREVDLHFMKKIPPGAEASNILVGELEFLDRTVVAFVRLSPAVLLQGLAEVPIPSRFLFILLGPLGKGQQYHEIGRSIATLMTDEVFHDVAYKAKDRNDLVSGIDEFLDQVTVLPPGEWDPSIRIEPPKNVPSQEKRKTPSLPNG-----TAAHGG-----------------------PEQHGGHSGPELQRTGRIFGGLILDIKRKAPFFWSDFRDAFSLQCLASFLFLYCACMSPVITFGGLLGEATEGRISAIESLFGASMTGIAYSLFGGQPLTILGSTGPVLVFEKILFKFCKEYGLSYLSLRASIGLWTATLCIILVATDASSLVCYITRFTEEAFASLICIIFIYEALEKLFELSESYPINMHNDLELLTQYSCNCMEPHSPSNDTL--KEWRESNI-------------SASDII----WGNLTVSE-----------CRSLHGEYVGRACGHGHPYVPDVLFWSVILFFSTVTMSATLKQFKTSRYFPTKVRSIVSDFAVFLTILCMVLIDYAIGIPSPKLQVPSVFKPT--RDDRGWFVTPLGPNPWWTIIAAIIPALLCTILIFMDQQITAVIINRKEHKLKKGCGYHLDLLMVAVMLGVCSIMGLPWFVAATVLSITHVNSLKLESECSAPGEQPKFLGIREQRVTGLMIFILMGSSVFMTSILKFIPMPVLYGVFLYMGASSLKGIQLFDRIKLFWMPAKHQPDFIYLRHVPLRKVHLFTVIQMSCLGLLWIIKVSRA-AIVFPMMVLALVFVRKLMDFLFTKRELSWLDDLMPESKKKKLEDAEKEEEQ---SMLAMEDEGTVQLPLEGH--YRDDPSVINISDEMSKTAMWGNL 1096          
BLAST of slc4a-1 vs. UniProt/SwissProt
Match: sp|Q32LP4|S4A10_BOVIN (Sodium-driven chloride bicarbonate exchanger OS=Bos taurus OX=9913 GN=SLC4A10 PE=2 SV=1)

HSP 1 Score: 944.495 bits (2440), Expect = 0.000e+0
Identity = 545/1161 (46.94%), Postives = 743/1161 (64.00%), Query Frame = 2
Query:  125 DEPILDRG----FQFTHYHPSEDEIEDHRSQRALYIGVHMPPDXXXXXXXXXXXXXXXXXXXXXDKKDYLTEIAEDDTEKATDPSQHVMFLLG-EDEDEE--THNLFCEMDELRLDDEGEPEWKETARWIKFEEDVEEGGERWSKPHVASLSLYSLFEVRNCITSAVNMFNVEANNFETIIEIILNKIVSEKKISPDQREKVKEMLQRKHVHLHERRHKSNAKGSQLPLIRSLADIGKKYSS-KEVDKVQLQRRNSDYPTKFTRFDANXXXXXXXXXXXXXYVDKNRIDVDQCGSD--------NLASQKFDLHFFKKIPLGAETSNIMVGETDFLNQMVVVFIRLKEAVILGELTEVPVPTRFVFVMLGPQGSAVKNHEIGRSMATLMSDDVFHDVAYKARNLDDLLAGIDEFLSNCTVLPPAEWDPSIRIEPPKSGPIA--RKVPSMPNGAQALLTASGDGRXXXXXXXXXXXXXXASVVNKLQPVEEESHADPTLRRTGRLFGGLIEDVKRKAPFYLSDFKDAIHVQCFASFFFLYFACLTPIITFGGLLVQATGGYLGAIESILSGTIVGVVYSLFSGQPLTIMGSTGPVLVFESIVYNICERMRWDYLPFRLWIGVWIAAYLFLMVAFDLSALVRYITRFTEESFAALIALIFMVEAFKKLFLIVDYYPIDTRWNIDMIKNRTCECF----PRNATAMDAFFQKNNKPSNVYMPPMLYPVPLNSSVIDIVNNIDWQNISNYHFTWDYKKYRLICTKWGGIWTGSGCGNY--FIPDVFFFSCLLFIGTFVLSYGLKMMRNAQFFPNWVRSLISDFAVMIAISSMTLLDWSLGFHTPKLNVPAKFEPTLGYKMRGWVIPALGKNPWWTIIIAMGPALLAVILIFMDQQITAVIVNRKENKLKKGSGYHXXXXXXXXXXXXXXXXGIPWFVAATVLSINHVMSLKKESENTAPGERPVFLGCREQRVTGTIIFLVIGLSVFLTPLLKRIPMAVLYGVFLFMGVASLKGVQLMQRISLFFMPAKYQPDYIFLRYVPLRRVHXXXXXXXXXXXXXXXXXXXNVMSICFPIMVLALCFVRKGLEYLFTYNELKWLDDIMPNHKKPPQDDNENDIEKCGSTELIKMTETNLEFNSSTNKVIRSNDSGINISEEMGKTAIWKQL 3535
            +E ++DRG       TH+     E ED    R L+IGVH+P     + + +R R      + +  ++D   E   +     T PSQ V F+LG ED+DEE   H+LF E+DE+   +  + EW+ETARW+KFEEDVE+GGERWSKP+VA+LSL+SLFE+R+CI +   + ++ AN  E I +++L++ VS  +++ D R +V E L ++H H ++++  +     ++P++RS ADIGKK S    +DK   Q  +            + S+ +     S     + +     CG          +   ++ DLHF KKIP GAE SNI+VGE +FL++ VV F+RL  AV+L  L EVP+PTRF+F++LGP G   + HEIGRS+ATLM+D+VFHDVAYKA++ +DL++GIDEFL   TVLPP EWDPSIRIEPPK+ P    RK+P++PNG  A   A   G                             H+ P L+RTGRLFGGLI D+KRKAP++ SDF DA+ +QC ASF FLY AC++P+ITFGGLL +AT G + AIES+   ++ G+ YSLF GQPLTI+GSTGPVLVFE I++  C+     YL  R  IG+W A    ++VA D S+LV YITRFTEE+FA+LI +IF+ EA +KLF + + YPI+   +++++   +C C     P N T       K  + SN+             S  DI+    W+N++              CT   G + G  CG+   ++PDV F+S +LF  T  LS  LK  + +++FP  VRS++SDFAV + I  M L+D+++G  +PKL VP+ F+PT     RGW +  LG NPWWT+I A+ PALL  ILIFMDQQITAVI+NRKE+KLKKG GYHLDLL+VA+++ V SI+G+PWFVAATVLSI HV SLK ESE +APGE+P FLG REQRVTG +IF+++G SVF+T +LK IPM VLYGVFL+MG +SLKG+Q   RI LF+MPAK+QPD+I+LR+VPLR+VHLFT+IQ+  L LLW+IK     +I FP+MVLAL FVRK +++LFT  EL WLDD+MP  KK   +D E + E+   + L    E  ++     +   R + S INIS+EM KTA+W+ L
Sbjct:   19 EEAVVDRGGTRSILKTHF-----EKEDLEGHRTLFIGVHVP--LGGRKSHRRHRHRGHKHRKRDRERDSGLEDGRESPSFDT-PSQRVQFILGTEDDDEEHIPHDLFTELDEICWREGEDAEWRETARWLKFEEDVEDGGERWSKPYVATLSLHSLFELRSCILNGTVLLDMHANTLEEIADMVLDQQVSSGQLNEDVRHRVHEALMKQHHHQNQKKLTN-----RIPIVRSFADIGKKQSEPNSMDKNAGQVVSPQSAPACVENKNDVSRENSTVDFSKGLGGQQKGHTSPCGMKQRHEKGPPHQQDREVDLHFMKKIPPGAEASNILVGELEFLDRTVVAFVRLSPAVLLQGLAEVPIPTRFLFILLGPLGKGQQYHEIGRSIATLMTDEVFHDVAYKAKDRNDLVSGIDEFLDQVTVLPPGEWDPSIRIEPPKNVPSQEKRKIPAVPNGTAAHGEAEPHG----------------------------GHSGPELQRTGRLFGGLILDIKRKAPYFWSDFTDALSLQCLASFLFLYCACMSPVITFGGLLGEATEGRISAIESLFGASMTGIAYSLFGGQPLTILGSTGPVLVFEKILFKFCKEYGLSYLSLRASIGLWTATLCIILVATDASSLVCYITRFTEEAFASLICIIFIYEALEKLFELSEAYPINMHNDLELLTQYSCNCVEPHNPSNNTL------KEWRESNI-------------SASDII----WENLTVSE-----------CTSLHGEYVGRACGHEHPYVPDVLFWSVILFFSTVTLSATLKQFKTSRYFPTKVRSIVSDFAVFLTILCMVLIDYAIGIPSPKLQVPSVFKPT--RDDRGWFVTPLGPNPWWTVIAAIIPALLCTILIFMDQQITAVIINRKEHKLKKGCGYHLDLLMVAVMLGVCSIMGLPWFVAATVLSITHVNSLKLESECSAPGEQPKFLGIREQRVTGLMIFILMGSSVFMTSILKFIPMPVLYGVFLYMGASSLKGIQFFDRIKLFWMPAKHQPDFIYLRHVPLRKVHLFTVIQMSCLGLLWIIKVSRA-AIVFPMMVLALVFVRKLMDFLFTKRELSWLDDLMPESKKKKLEDAEKEEEQ---SMLAMEDEGTVQLPLEGH--YRDDPSVINISDEMSKTALWRNL 1096          
BLAST of slc4a-1 vs. UniProt/SwissProt
Match: sp|Q6U841|S4A10_HUMAN (Sodium-driven chloride bicarbonate exchanger OS=Homo sapiens OX=9606 GN=SLC4A10 PE=1 SV=1)

HSP 1 Score: 939.488 bits (2427), Expect = 0.000e+0
Identity = 544/1161 (46.86%), Postives = 741/1161 (63.82%), Query Frame = 2
Query:  125 DEPILDRG----FQFTHYHPSEDEIEDHRSQRALYIGVHMPPDXXXXXXXXXXXXXXXXXXXXXDKKDYLTEIAEDDTEKATDPSQHVMFLLG-EDEDEE--THNLFCEMDELRLDDEGEPEWKETARWIKFEEDVEEGGERWSKPHVASLSLYSLFEVRNCITSAVNMFNVEANNFETIIEIILNKIVSEKKISPDQREKVKEMLQRKHVHLHERRHKSNAKGSQLPLIRSLADIGKKYSS-KEVDKVQLQRRNSDYPTKFTRFDANXXXXXXXXXXXXXYVDKNRIDVDQCGSD--------NLASQKFDLHFFKKIPLGAETSNIMVGETDFLNQMVVVFIRLKEAVILGELTEVPVPTRFVFVMLGPQGSAVKNHEIGRSMATLMSDDVFHDVAYKARNLDDLLAGIDEFLSNCTVLPPAEWDPSIRIEPPKSGPIA--RKVPSMPNGAQALLTASGDGRXXXXXXXXXXXXXXASVVNKLQPVEEESHADPTLRRTGRLFGGLIEDVKRKAPFYLSDFKDAIHVQCFASFFFLYFACLTPIITFGGLLVQATGGYLGAIESILSGTIVGVVYSLFSGQPLTIMGSTGPVLVFESIVYNICERMRWDYLPFRLWIGVWIAAYLFLMVAFDLSALVRYITRFTEESFAALIALIFMVEAFKKLFLIVDYYPIDTRWNIDMIKNRTCECF----PRNATAMDAFFQKNNKPSNVYMPPMLYPVPLNSSVIDIVNNIDWQNISNYHFTWDYKKYRLICTKWGGIWTGSGCG--NYFIPDVFFFSCLLFIGTFVLSYGLKMMRNAQFFPNWVRSLISDFAVMIAISSMTLLDWSLGFHTPKLNVPAKFEPTLGYKMRGWVIPALGKNPWWTIIIAMGPALLAVILIFMDQQITAVIVNRKENKLKKGSGYHXXXXXXXXXXXXXXXXGIPWFVAATVLSINHVMSLKKESENTAPGERPVFLGCREQRVTGTIIFLVIGLSVFLTPLLKRIPMAVLYGVFLFMGVASLKGVQLMQRISLFFMPAKYQPDYIFLRYVPLRRVHXXXXXXXXXXXXXXXXXXXNVMSICFPIMVLALCFVRKGLEYLFTYNELKWLDDIMPNHKKPPQDDNENDIEKCGSTELIKMTETNLEFNSSTNKVIRSNDSGINISEEMGKTAIWKQL 3535
            +E ++DRG       TH+     E ED    R L+IGVH+P     + + +R R      + +  ++D   E   +     T PSQ V F+LG ED+DEE   H+LF E+DE+   +  + EW+ETARW+KFEEDVE+GGERWSKP+VA+LSL+SLFE+R+CI +   + ++ AN  E I +++L++ VS  +++ D R +V E L ++H H ++++  +     ++P++RS ADIGKK S    +DK   Q  +            + S+ +     S     + +     CG          +   ++ DLHF KKIP GAE SNI+VGE +FL++ VV F+RL  AV+L  L EVP+PTRF+F++LGP G   + HEIGRS+ATLM+D+VFHDVAYKA++ +DL++GIDEFL   TVLPP EWDPSIRIEPPK+ P    RK+P++PNG  A   A   G                             H+ P L+RTGR+FGGLI D+KRKAP++ SDF+DA  +QC ASF FLY AC++P+ITFGGLL +AT G + AIES+   ++ G+ YSLF GQPLTI+GSTGPVLVFE I++  C+     YL  R  IG+W A    ++VA D S+LV YITRFTEE+FA+LI +IF+ EA +KLF + + YPI+   +++++   +C C     P N T       K  + SN+             S  DI+    W+N++              C    G + G  CG  + ++PDV F+S +LF  T  LS  LK  + +++FP  VRS++SDFAV + I  M L+D+++G  +PKL VP+ F+PT     RGW +  LG NPWWT+I A+ PALL  ILIFMDQQITAVI+NRKE+KLKKG GYHLDLL+VA+++ V SI+G+PWFVAATVLSI HV SLK ESE +APGE+P FLG REQRVTG +IF+++G SVF+T +LK IPM VLYGVFL+MG +SLKG+Q   RI LF+MPAK+QPD+I+LR+VPLR+VHLFTIIQ+  L LLW+IK     +I FP+MVLAL FVRK ++ LFT  EL WLDD+MP  KK   +D E + E+   + L    E  ++     +   R + S INIS+EM KTA+W+ L
Sbjct:   20 EEAVVDRGGTRSILKTHF-----EKEDLEGHRTLFIGVHVP--LGGRKSHRRHRHRGHKHRKRDRERDSGLEDGRESPSFDT-PSQRVQFILGTEDDDEEHIPHDLFTELDEICWREGEDAEWRETARWLKFEEDVEDGGERWSKPYVATLSLHSLFELRSCILNGTVLLDMHANTLEEIADMVLDQQVSSGQLNEDVRHRVHEALMKQHHHQNQKKLTN-----RIPIVRSFADIGKKQSEPNSMDKNAGQVVSPQSAPACVENKNDVSRENSTVDFSKGLGGQQKGHTSPCGMKQRHEKGPPHQQEREVDLHFMKKIPPGAEASNILVGELEFLDRTVVAFVRLSPAVLLQGLAEVPIPTRFLFILLGPLGKGQQYHEIGRSIATLMTDEVFHDVAYKAKDRNDLVSGIDEFLDQVTVLPPGEWDPSIRIEPPKNVPSQEKRKIPAVPNGTAAHGEAEPHG----------------------------GHSGPELQRTGRIFGGLILDIKRKAPYFWSDFRDAFSLQCLASFLFLYCACMSPVITFGGLLGEATEGRISAIESLFGASMTGIAYSLFGGQPLTILGSTGPVLVFEKILFKFCKEYGLSYLSLRASIGLWTATLCIILVATDASSLVCYITRFTEEAFASLICIIFIYEALEKLFELSEAYPINMHNDLELLTQYSCNCVEPHNPSNGTL------KEWRESNI-------------SASDII----WENLTVSE-----------CKSLHGEYVGRACGHDHPYVPDVLFWSVILFFSTVTLSATLKQFKTSRYFPTKVRSIVSDFAVFLTILCMVLIDYAIGIPSPKLQVPSVFKPT--RDDRGWFVTPLGPNPWWTVIAAIIPALLCTILIFMDQQITAVIINRKEHKLKKGCGYHLDLLMVAVMLGVCSIMGLPWFVAATVLSITHVNSLKLESECSAPGEQPKFLGIREQRVTGLMIFILMGSSVFMTSILKFIPMPVLYGVFLYMGASSLKGIQFFDRIKLFWMPAKHQPDFIYLRHVPLRKVHLFTIIQMSCLGLLWIIKVSRA-AIVFPMMVLALVFVRKLMDLLFTKRELSWLDDLMPESKKKKLEDAEKEEEQ---SMLAMEDEGTVQLPLEGH--YRDDPSVINISDEMSKTALWRNL 1097          
BLAST of slc4a-1 vs. UniProt/SwissProt
Match: sp|Q8JZR6|S4A8_MOUSE (Electroneutral sodium bicarbonate exchanger 1 OS=Mus musculus OX=10090 GN=Slc4a8 PE=2 SV=1)

HSP 1 Score: 927.161 bits (2395), Expect = 0.000e+0
Identity = 544/1158 (46.98%), Postives = 735/1158 (63.47%), Query Frame = 2
Query:  125 DEPILDRGFQFT--HYHPSEDEIEDHRSQRALYIGVHMP----PDXXXXXXXXXXXXXXXXXXXXXDKKDYLTEIAEDDTEKATDPSQHVMFLLGEDEDEE--THNLFCEMDELRLDDEGEPEWKETARWIKFEEDVEEGGERWSKPHVASLSLYSLFEVRNCITSAVNMFNVEANNFETIIEIILNKIVSEKKISPDQREKVKEMLQRKHVHLHERRHKSNAKGSQLPLIRSLADIGKKYSSKEVDKVQLQRRNSDY-PTKFTRFDANXXXXXXXXXXXXXYVDKNRIDVDQCGSDNLASQKFDLHFFKKIPLGAETSNIMVGETDFLNQMVVVFIRLKEAVILGELTEVPVPTRFVFVMLGPQGSAVKNHEIGRSMATLMSDDVFHDVAYKARNLDDLLAGIDEFLSNCTVLPPAEWDPSIRIEPPKSGPIA--RKVPSMPNGAQALLTASGDGRXXXXXXXXXXXXXXASVVNKLQPVEEESHADPTLRRTGRLFGGLIEDVKRKAPFYLSDFKDAIHVQCFASFFFLYFACLTPIITFGGLLVQATGGYLGAIESILSGTIVGVVYSLFSGQPLTIMGSTGPVLVFESIVYNICERMRWDYLPFRLWIGVWIAAYLFLMVAFDLSALVRYITRFTEESFAALIALIFMVEAFKKLFLIVDYYPIDTRWNIDMIKNRTCEC-FPRNATAMDAFFQKNNKPSNVYMPPMLYPVPLNSSVIDIVNNIDWQNISNYHFTWDYKKYRLICTKWGGIWTGSGCGNY--FIPDVFFFSCLLFIGTFVLSYGLKMMRNAQFFPNWVRSLISDFAVMIAISSMTLLDWSLGFHTPKLNVPAKFEPTLGYKMRGWVIPALGKNPWWTIIIAMGPALLAVILIFMDQQITAVIVNRKENKLKKGSGYHXXXXXXXXXXXXXXXXGIPWFVAATVLSINHVMSLKKESENTAPGERPVFLGCREQRVTGTIIFLVIGLSVFLTPLLKRIPMAVLYGVFLFMGVASLKGVQLMQRISLFFMPAKYQPDYIFLRYVPLRRVHXXXXXXXXXXXXXXXXXXXNVMSICFPIMVLALCFVRKGLEYLFTYNELKWLDDIMPNHKKPPQDDNENDIEKCGSTEL------IKMTETNLEFNSSTNKVIRSNDSGINISEEMGKTAIWKQLS 3538
            +E ++D+G   T  + H  ++E+E HR+   LY+GV MP      R H+   Q+ RR     +G    ++ L  +A D       PSQ V F+LG +EDEE   H LF E+DE+ + +  + EWKETARW+KFEEDVE+GGERWSKP+VA+LSL+SLFE+R+C+ +   + ++ A++ E I ++IL++    + +S   R KV+E L +KH H +ERR     + + +P++RS A++GKK S    D   + R      P   T  +                  KN ++   C    +   K DLHF KKIP GAE SN++VGE D L++ +V F+RL  AV+L  LTEVP+PTRF+F++LGP G   + HEIGRSMAT+M+D++FHDVAYKA+  DDLLAGIDEFL   TVLPP EWDPSIRIEPPK+ P    RK+P +PNG                             V  ++P     H+ P L RTGRLFGGL+ DVKRKAP+Y SD++DA+ +QC ASF FLY AC++P+ITFGGLL +AT G + AIES+   ++ G+ YSLF+GQPLTI+GSTGPVLVFE I++  C+     YL  R  IG+W A    ++VA D S+LV YITRFTEE+FA+LI +IF+ EA +KL  + + YPI     +D +    C C  P N       + K++   N+                 +   ++W N++              C +  G + GS CG++  + PDV F+SC+LF  TF++S  LK  + +++FP  VRS++SDFAV + I +M +LD+ +G  +PKL VP  F+PT     RGW I  +G NPWWT+I A+ PALL  ILIFMDQQITAVI+NRKE+KLKKG GYHLDLL+VA+++ V SI+G+PWFVAATVLSI HV SLK ESE +APGE+P FLG REQRVTG +IF+++G SVF+T +LK IPM VLYGVFL+MGV+SL+G+Q   R+ LF MPAK+QPD+I+LR+VPLR+VHLFT++Q+  LVLLWVIK     +I FP+MVLAL FVRK ++  F+  EL WLDD+MP  KK   DD +   E+     L        +    L  +   +   R + S INIS+EM KT +WK LS
Sbjct:   19 EEAVVDQGGTSTILNIHYEKEELEGHRT---LYVGVRMPLGRQSHRHHRTHGQKHRRRGGRGKGASQGEEGLEALAHDT------PSQRVQFILGTEEDEEHVPHELFTELDEICMKEGEDAEWKETARWLKFEEDVEDGGERWSKPYVATLSLHSLFELRSCLINGSVLLDMRASSIEEISDLILDQQELLRDLSDSVRVKVREALLKKHHHQNERR-----RNNLIPIVRSFAEVGKKQS----DPHSMDRDGQTVSPQSATNLEV-----------------KNGVN---CEHSPVDLSKVDLHFMKKIPTGAEASNVLVGEVDTLDRPIVAFVRLSPAVLLSGLTEVPIPTRFLFILLGPVGKGQQYHEIGRSMATIMTDEIFHDVAYKAKERDDLLAGIDEFLDQVTVLPPGEWDPSIRIEPPKNVPSQEKRKMPGVPNGN----------------------------VCHIEPEPHGGHSGPELERTGRLFGGLVLDVKRKAPWYWSDYRDALSLQCLASFLFLYCACMSPVITFGGLLGEATEGRISAIESLFGASMTGIAYSLFAGQPLTILGSTGPVLVFEKILFKFCKDYALSYLSLRALIGLWTAFLCIVLVATDASSLVCYITRFTEEAFASLICIIFIYEAIEKLIHLAETYPIHMHSQLDHLSLYYCRCVLPENPNNHTLQYWKDH---NI-----------------LAAEVNWANLTVSE-----------CQEMHGEFMGSACGHHGPYTPDVLFWSCILFFATFIVSSTLKTFKTSRYFPTRVRSMVSDFAVFLTIFTMVVLDFLIGVPSPKLQVPNVFKPT--RDDRGWFINPIGPNPWWTVIAAIIPALLCTILIFMDQQITAVIINRKEHKLKKGCGYHLDLLMVAVMLGVCSIMGLPWFVAATVLSITHVNSLKLESECSAPGEQPKFLGIREQRVTGLMIFVLMGCSVFMTAVLKFIPMPVLYGVFLYMGVSSLQGIQFFDRLKLFGMPAKHQPDFIYLRHVPLRKVHLFTLVQLTCLVLLWVIKASPA-AIVFPMMVLALVFVRKVMDLCFSKRELSWLDDLMPESKKKKLDDAKKKEEEEAEKMLDIGGDKFPLESRKLLSSPGKSSSFRCDPSEINISDEMPKTTVWKALS 1076          
BLAST of slc4a-1 vs. TrEMBL
Match: A0A0H3YF38 (Anion exchange protein OS=Schmidtea mediterranea OX=79327 GN=slc4a-1 PE=2 SV=1)

HSP 1 Score: 2302.32 bits (5965), Expect = 0.000e+0
Identity = 1230/1230 (100.00%), Postives = 1230/1230 (100.00%), Query Frame = 2
Query:  107 MDITVGDEPILDRGFQFTHYHPSEDEIEDHRSQRALYIGVHMPPDXXXXXXXXXXXXXXXXXXXXXDKKDYLTEIAEDDTEKATDPSQHVMFLLGEDEDEETHNLFCEMDELRLDDEGEPEWKETARWIKFEEDVEEGGERWSKPHVASLSLYSLFEVRNCITSAVNMFNVEANNFETIIEIILNKIVSEKKISPDQREKVKEMLQRKHVHLHERRHKSNAKGSQLPLIRSLADIGKKYSSKEVDKVQLQRRNSDYPTKFTRFDANXXXXXXXXXXXXXYVDKNRIDVDQCGSDNLASQKFDLHFFKKIPLGAETSNIMVGETDFLNQMVVVFIRLKEAVILGELTEVPVPTRFVFVMLGPQGSAVKNHEIGRSMATLMSDDVFHDVAYKARNLDDLLAGIDEFLSNCTVLPPAEWDPSIRIEPPKSGPIARKVPSMPNGAQALLTASGDGRXXXXXXXXXXXXXXASVVNKLQPVEEESHADPTLRRTGRLFGGLIEDVKRKAPFYLSDFKDAIHVQCFASFFFLYFACLTPIITFGGLLVQATGGYLGAIESILSGTIVGVVYSLFSGQPLTIMGSTGPVLVFESIVYNICERMRWDYLPFRLWIGVWIAAYLFLMVAFDLSALVRYITRFTEESFAALIALIFMVEAFKKLFLIVDYYPIDTRWNIDMIKNRTCECFPRNATAMDAFFQKNNKPSNVYMPPMLYPVPLNSSVIDIVNNIDWQNISNYHFTWDYKKYRLICTKWGGIWTGSGCGNYFIPDVFFFSCLLFIGTFVLSYGLKMMRNAQFFPNWVRSLISDFAVMIAISSMTLLDWSLGFHTPKLNVPAKFEPTLGYKMRGWVIPALGKNPWWTIIIAMGPALLAVILIFMDQQITAVIVNRKENKLKKGSGYHXXXXXXXXXXXXXXXXGIPWFVAATVLSINHVMSLKKESENTAPGERPVFLGCREQRVTGTIIFLVIGLSVFLTPLLKRIPMAVLYGVFLFMGVASLKGVQLMQRISLFFMPAKYQPDYIFLRYVPLRRVHXXXXXXXXXXXXXXXXXXXNVMSICFPIMVLALCFVRKGLEYLFTYNELKWLDDIMPNHKKPPQDDNENDIEKCGSTELIKMTETNLEFNSSTNKVIRSNDSGINISEEMGKTAIWKQLSGGTXXXXXXXXXXXXXXXXXXDRSGNKDMESGDQGNSDNSHVQPLLNDSRESGRDNKHHYMTTPEIVVNPPSARESPELKHQNPKV 3796
            MDITVGDEPILDRGFQFTHYHPSEDEIEDHRSQRALYIGVHMPPDRIHQPTRQRRRRHKKSKQGQHDKKDYLTEIAEDDTEKATDPSQHVMFLLGEDEDEETHNLFCEMDELRLDDEGEPEWKETARWIKFEEDVEEGGERWSKPHVASLSLYSLFEVRNCITSAVNMFNVEANNFETIIEIILNKIVSEKKISPDQREKVKEMLQRKHVHLHERRHKSNAKGSQLPLIRSLADIGKKYSSKEVDKVQLQRRNSDYPTKFTRFDANSSQPSIIKSSSSIYVDKNRIDVDQCGSDNLASQKFDLHFFKKIPLGAETSNIMVGETDFLNQMVVVFIRLKEAVILGELTEVPVPTRFVFVMLGPQGSAVKNHEIGRSMATLMSDDVFHDVAYKARNLDDLLAGIDEFLSNCTVLPPAEWDPSIRIEPPKSGPIARKVPSMPNGAQALLTASGDGRGGNNNGTPSSGTGPASVVNKLQPVEEESHADPTLRRTGRLFGGLIEDVKRKAPFYLSDFKDAIHVQCFASFFFLYFACLTPIITFGGLLVQATGGYLGAIESILSGTIVGVVYSLFSGQPLTIMGSTGPVLVFESIVYNICERMRWDYLPFRLWIGVWIAAYLFLMVAFDLSALVRYITRFTEESFAALIALIFMVEAFKKLFLIVDYYPIDTRWNIDMIKNRTCECFPRNATAMDAFFQKNNKPSNVYMPPMLYPVPLNSSVIDIVNNIDWQNISNYHFTWDYKKYRLICTKWGGIWTGSGCGNYFIPDVFFFSCLLFIGTFVLSYGLKMMRNAQFFPNWVRSLISDFAVMIAISSMTLLDWSLGFHTPKLNVPAKFEPTLGYKMRGWVIPALGKNPWWTIIIAMGPALLAVILIFMDQQITAVIVNRKENKLKKGSGYHLDLLVVAILILVNSILGIPWFVAATVLSINHVMSLKKESENTAPGERPVFLGCREQRVTGTIIFLVIGLSVFLTPLLKRIPMAVLYGVFLFMGVASLKGVQLMQRISLFFMPAKYQPDYIFLRYVPLRRVHLFTIIQIILLVLLWVIKTINVMSICFPIMVLALCFVRKGLEYLFTYNELKWLDDIMPNHKKPPQDDNENDIEKCGSTELIKMTETNLEFNSSTNKVIRSNDSGINISEEMGKTAIWKQLSGGTKSGHSKNKKRKKREHNAADRSGNKDMESGDQGNSDNSHVQPLLNDSRESGRDNKHHYMTTPEIVVNPPSARESPELKHQNPKV
Sbjct:    1 MDITVGDEPILDRGFQFTHYHPSEDEIEDHRSQRALYIGVHMPPDRIHQPTRQRRRRHKKSKQGQHDKKDYLTEIAEDDTEKATDPSQHVMFLLGEDEDEETHNLFCEMDELRLDDEGEPEWKETARWIKFEEDVEEGGERWSKPHVASLSLYSLFEVRNCITSAVNMFNVEANNFETIIEIILNKIVSEKKISPDQREKVKEMLQRKHVHLHERRHKSNAKGSQLPLIRSLADIGKKYSSKEVDKVQLQRRNSDYPTKFTRFDANSSQPSIIKSSSSIYVDKNRIDVDQCGSDNLASQKFDLHFFKKIPLGAETSNIMVGETDFLNQMVVVFIRLKEAVILGELTEVPVPTRFVFVMLGPQGSAVKNHEIGRSMATLMSDDVFHDVAYKARNLDDLLAGIDEFLSNCTVLPPAEWDPSIRIEPPKSGPIARKVPSMPNGAQALLTASGDGRGGNNNGTPSSGTGPASVVNKLQPVEEESHADPTLRRTGRLFGGLIEDVKRKAPFYLSDFKDAIHVQCFASFFFLYFACLTPIITFGGLLVQATGGYLGAIESILSGTIVGVVYSLFSGQPLTIMGSTGPVLVFESIVYNICERMRWDYLPFRLWIGVWIAAYLFLMVAFDLSALVRYITRFTEESFAALIALIFMVEAFKKLFLIVDYYPIDTRWNIDMIKNRTCECFPRNATAMDAFFQKNNKPSNVYMPPMLYPVPLNSSVIDIVNNIDWQNISNYHFTWDYKKYRLICTKWGGIWTGSGCGNYFIPDVFFFSCLLFIGTFVLSYGLKMMRNAQFFPNWVRSLISDFAVMIAISSMTLLDWSLGFHTPKLNVPAKFEPTLGYKMRGWVIPALGKNPWWTIIIAMGPALLAVILIFMDQQITAVIVNRKENKLKKGSGYHLDLLVVAILILVNSILGIPWFVAATVLSINHVMSLKKESENTAPGERPVFLGCREQRVTGTIIFLVIGLSVFLTPLLKRIPMAVLYGVFLFMGVASLKGVQLMQRISLFFMPAKYQPDYIFLRYVPLRRVHLFTIIQIILLVLLWVIKTINVMSICFPIMVLALCFVRKGLEYLFTYNELKWLDDIMPNHKKPPQDDNENDIEKCGSTELIKMTETNLEFNSSTNKVIRSNDSGINISEEMGKTAIWKQLSGGTKSGHSKNKKRKKREHNAADRSGNKDMESGDQGNSDNSHVQPLLNDSRESGRDNKHHYMTTPEIVVNPPSARESPELKHQNPKV 1230          
BLAST of slc4a-1 vs. TrEMBL
Match: A0A4S2LRB5 (Anion exchange protein OS=Opisthorchis felineus OX=147828 GN=CRM22_005384 PE=3 SV=1)

HSP 1 Score: 1189.48 bits (3076), Expect = 0.000e+0
Identity = 668/1333 (50.11%), Postives = 857/1333 (64.29%), Query Frame = 2
Query:  119 VGDEPILDRGFQFTHYHPSEDEIEDHRSQRALYIGVHMPPDXXXXXXXXXXXXXXXXXXXXXDKKDYLTEIAEDDTEK-----ATDPSQHVMFLLGE-DEDEET-HNLFCEMDEL--RLDDEGEPEWKETARWIKFEEDVEEGGERWSKPHVASLSLYSLFEVRNCITSAVNMFNVEANNFETIIEIILNKIVSEKKISPDQREKVKEMLQRKHVHLHERRHK--SNAKGSQLPLIRSLADIGKKYSSKEVDKVQLQRRNSDYPTKFTRFDANXXXXXXXXXXXXXYVDKNRIDVDQCGSDNLASQKFDLHFFKKIPLGAETSNIMVGETDFLNQMVVVFIRLKEAVILGELTEVPVPTRFVFVMLGPQGSAVKNHEIGRSMATLMSDDVFHDVAYKARNLDDLLAGIDEFLSNCTVLPPAEWDPSIRIEPPKSGPI--ARKVPSMPNGAQA--------------------LLTASGDGRXXXXXXXXXXXXXXA-------------SVVNKLQPVEEESHA-------------DPTLRRTGRLFGGLIEDVKRKAPFYLSDFKDAIHVQCFASFFFLYFACLTPIITFGGLLVQATGGYLGAIESILSGTIVGVVYSLFSGQPLTIMGSTGPVLVFESIVYNICERMRWDYLPFRLWIGVWIAAYLFLMVAFDLSALVRYITRFTEESFAALIALIFMVEAFKKLFLIVDYYPIDTRWNIDMIKNRTCECF-PRNATAMDAFFQKNNKPSNVYMPPML---YPVPLNSSVID----IVNNIDWQNISNYHFTWDYKKYRLICTKWGGIWTGSGCGNYFIPDVFFFSCLLFIGTFVLSYGLKMMRNAQFFPNWVRSLISDFAVMIAISSMTLLDWSLGFHTPKLNVPAKFEPTLGYKMRGWVIPALGKNPWWTIIIAMGPALLAVILIFMDQQITAVIVNRKENKLKKGSGYHXXXXXXXXXXXXXXXXGIPWFVAATVLSINHVMSLKKESENTAPGERPVFLGCREQRVTGTIIFLVIGLSVFLTPLLKRIPMAVLYGVFLFMGVASLKGVQLMQRISLFFMPAKYQPDYIFLRYVPLRRVHXXXXXXXXXXXXXXXXXXXNVMSICFPIMVLALCFVRKGLEYLFTYNELKWLDDIMPNHKKPPQDDNENDIEKCGSTELIKMTETNLEFNSSTNKVIRSNDSGINISEEMGKTAIWKQLSGGTXXXXXXXXXXXXXXXXXXDRSGNK-----------------DMESGDQGNSDNSH--------------VQPLL------------NDSRESGRDNKHHYMTTPEIVVNPPSARESPELKHQN 3787
            + DEP++D   ++    PS+DEI  HRS+  + IG+   P                +    H  +     +   D E        DPS++VMFLLGE D DEE  H+LFCE+DEL   L   GE EW+E ARWIKFEEDVEE GERWSKPHVA+LSL+SLFE+RNC+ + V M N+EA   E I ++ LN +VSE ++ PD RE + E+L R+HVHLHER     S    S +PLIRSLADIGK+YSSKEVDK    + +    + +   D+     +   ++ +     + +     GS      K+DLHF KK+P G+ETSNI+VGET FL   + VFIRL+EAV+LG+LTEVPVPTRF+F+ LG  G+A K  EIGRSM  LMSDDVFHDVAYKA++  D LAG+DEFLS  TVLPP EWDPSIRIEPP S P   +RK  + PNG Q                      LTA GD   G       S T                SV ++ + V  E+               DP L+RTG +FGGL  D++R+AP YLSDF DA+HVQC ASF FLYFACLTPIITFGGLL QATGGYLG IESILSG +VG++YSLFSGQPLTIMGSTGPVL+FE IVY +C+R+ W YL FRLWIG W++  L +MVA DLSALV+YITRFTEESFA LIALIF++EA KK++ +  YY ++  W+   + +  C C  P N+T  D       K   V +P +      + ++++ +D    +   IDW NIS   F+WD  ++R +CT   G WTG+ C  +++PDVFF SC+LFI TF ++  LK MR + FFP  VR+ ISDF+V+IAI+  TL D+ LG HTPKL VP +F PT+GY+ RGW+IPA   NPWW+ ++A+GPAL+A ILIFMDQQITAVIVNR+ENKLKKG+GYHLDLL+V++ I++NSILGIPWFVAATVLSINHV+SLKKESE +APGERPV+LGCREQRVTG +IFL IGLSVF+T LL RIPMAVLYG+FLFMG++SL GVQ++QRI L FMP KYQPDY +LR+VPLRRVH+FT IQ+  L +LWVIK+++ ++I FPIMVLA+CF+RK L+++FT +ELKWLDDI+P  K   +  N   ++   S +++K    +     S  ++ +  +  INI+EE+ KT+IW+QLSGG      K + + K + ++      K                 D ES D G   N+               + PL             ND    G  +  H ++ P+I +NPPS   SPE  H+N
Sbjct:    7 LSDEPVVDSAARYHAGEPSQDEIAGHRSKPTMLIGL---PSTEGGAATSTLHGLSSAGSSSHRHRRRRKRVTSQDRETDPSAPPADPSEYVMFLLGECDGDEEQPHHLFCELDELWNDLTGSGETEWREAARWIKFEEDVEENGERWSKPHVATLSLFSLFELRNCLATGVMMLNLEAFTMEQIADLTLNILVSEGRVPPDLRESLTELLLRRHVHLHERHRPKLSTRAASNIPLIRSLADIGKRYSSKEVDKEITSQPSLAKISTYGGMDSLDPALAAHVAAHAQASGPSEV---MSGS---LQGKYDLHFLKKVPPGSETSNILVGETTFLPAPITVFIRLREAVLLGDLTEVPVPTRFLFIHLGVLGNAAKYREIGRSMGVLMSDDVFHDVAYKAKSRADFLAGLDEFLSAATVLPPGEWDPSIRIEPPPSIPSQDSRKTGTSPNGNQTSGQNAATVPVTQTDSVNVMEQLTAGGDRLAGLCLAAVGSATLLTQQTEDKSKGEVAKSVGSRPELVSLEALGGTGPDDAPGGHGNDPALQRTGIIFGGLARDIRRRAPHYLSDFTDALHVQCCASFIFLYFACLTPIITFGGLLSQATGGYLGTIESILSGAVVGILYSLFSGQPLTIMGSTGPVLIFEGIVYRMCQRLEWSYLSFRLWIGFWVSMMLLIMVALDLSALVKYITRFTEESFATLIALIFIIEALKKIYAVSKYYNVNLGWSPQALPHHNCTCAPPENSTDYDVLSAMYTKHPLVDVPLITSNNTQICISAADVDEAQFVSMTIDWNNISAGRFSWDSLQFRKVCTFLNGTWTGADCVPFYVPDVFFLSCILFIFTFAIAVYLKSMRTSLFFPARVRATISDFSVVIAIALTTLTDFFLGLHTPKLEVPHEFSPTVGYRRRGWIIPAFNGNPWWSALVALGPALVATILIFMDQQITAVIVNRRENKLKKGAGYHLDLLLVSVTIMINSILGIPWFVAATVLSINHVLSLKKESEASAPGERPVYLGCREQRVTGVLIFLFIGLSVFMTSLLGRIPMAVLYGIFLFMGISSLAGVQMIQRIGLIFMPIKYQPDYSYLRHVPLRRVHMFTAIQVTCLAMLWVIKSVDAVAILFPIMVLAMCFIRKALDFIFTQDELKWLDDILPGSKAKNRPRNVYRVKS--SNDVLK---DDRHLLGSGVQLEQIPEKRINIAEEVAKTSIWRQLSGGNVKDTVKPQTKTKSKDSSKRGRRRKTRDSVNADGPNPKNLGVDQESVDDGGEVNTKPVLFSIDPLGRPLSMDPLAERSTPNAPWNVGNDGLGHGAVDSSHILSMPQITINPPSTHGSPEATHRN 1325          
BLAST of slc4a-1 vs. TrEMBL
Match: G7YU35 (Anion exchange protein OS=Clonorchis sinensis OX=79923 GN=CLF_110944 PE=3 SV=1)

HSP 1 Score: 1187.94 bits (3072), Expect = 0.000e+0
Identity = 674/1340 (50.30%), Postives = 859/1340 (64.10%), Query Frame = 2
Query:  119 VGDEPILDRGFQFTHYHPSEDEIEDHRSQRALYIGVHMPPDXXXXXXXXXXXXXXXXXXXXXDKKDYLTEIAEDDTEK-----ATDPSQHVMFLLGE-DEDEET-HNLFCEMDEL--RLDDEGEPEWKETARWIKFEEDVEEGGERWSKPHVASLSLYSLFEVRNCITSAVNMFNVEANNFETIIEIILNKIVSEKKISPDQREKVKEMLQRKHVHLHERRHK--SNAKGSQLPLIRSLADIGKKYSSKEVDKVQLQRRNSDYPTKFTRFDANXXXXXXXXXXXXXYVDKNRIDVDQCGSDNLASQKFDLHFFKKIPLGAETSNIMVGETDFLNQMVVVFIRLKEAVILGELTEVPVPTRFVFVMLGPQGSAVKNHEIGRSMATLMSDDVFHDVAYKARNLDDLLAGIDEFLSNCTVLPPAEWDPSIRIEPPKSGPI--ARKVPSMPNGAQA--------------------LLTASGDGRXXXXXXXXXXXXXXA-------------SVVNKLQPVEEESHA-------------DPTLRRTGRLFGGLIEDVKRKAPFYLSDFKDAIHVQCFASFFFLYFACLTPIITFGGLLVQATGGYLGAIESILSGTIVGVVYSLFSGQPLTIMGSTGPVLVFESIVYNICERMRWDYLPFRLWIGVWIAAYLFLMVAFDLSALVRYITRFTEESFAALIALIFMVEAFKKLFLIVDYYPIDTRWNIDMIKNRTCECF-PRNATAMDAFFQKNNKPSNVYMPPMLYPVPL---NSSVIDIVN-----------NIDWQNISNYHFTWDYKKYRLICTKWGGIWTGSGCGNYFIPDVFFFSCLLFIGTFVLSYGLKMMRNAQFFPNWVRSLISDFAVMIAISSMTLLDWSLGFHTPKLNVPAKFEPTLGYKMRGWVIPALGKNPWWTIIIAMGPALLAVILIFMDQQITAVIVNRKENKLKKGSGYHXXXXXXXXXXXXXXXXGIPWFVAATVLSINHVMSLKKESENTAPGERPVFLGCREQRVTGTIIFLVIGLSVFLTPLLKRIPMAVLYGVFLFMGVASLKGVQLMQRISLFFMPAKYQPDYIFLRYVPLRRVHXXXXXXXXXXXXXXXXXXXNVMSICFPIMVLALCFVRKGLEYLFTYNELKWLDDIMPNHKKPPQDDNENDIEKCGSTELIKMTETNLEFNSSTNKVIRSNDSGINISEEMGKTAIWKQLSGGTXXXXXXXXXXXXXXXXXXDRSGNK-----------------DMESGDQGN---------SDNSHVQPLLND---------------SRESGRD--NKHHYMTTPEIVVNPPSARESPELKHQN 3787
            + DEP++D G ++    PS+DEI  HRS+  + IG+   P                +    H  +     +   D E        DPS++VMFLLGE D DEE  H+LFCE+DEL   L   GE EW+E ARWIKFEEDVEE GERWSKPHVA+LSL+SLFE+RNC+ + V M N+EA   E I ++ LN +VSE ++ PD RE + E+L R+HVHLHER     S    S +PLIRSLADIGK+YSSKEVDK    + +    + +   D      +   ++ +     + +     GS      K+DLHF KK+P G+ETSNI+VGET FL   + VFIRL+EAV+LG+LTEVPVPTRF+F+ LG  G A K  EIGRSM  LMSDDVFHDVAYKA++  D LAG+DEFLS  TVLPP EWDPSIRIEPP S P   +RK  + PNG QA                     LTA GD   G       S T                SV ++ + V  E+               DP L+RTG +FGGL  D++R+AP YLSDF DA+HVQC ASF FLYFACLTPIITFGGLL QATGGYLG IESILSG +VG++YSLFSGQPLTIMGSTGPVL+FE IVY +C+R+ W YL FRLWIG W++  L +MVA DLSALV+YITRFTEESFA LIALIF++EA KK++ +  YY ++  W+ + + +  C C  P N+T  D         S +Y    L  VPL   N++ I I              IDW NIS   F+WD  ++R +CT   G WTG+ C  +++PDVFF SC+LFI TF ++  LK MR + FFP  VR+ ISDF+V+IAI+  TL D+ LG HTPKL VP +F PT+GY+ RGW+IPA   NPWW+ ++A+GPAL+A ILIFMDQQITAVIVNR+ENKL+KG+GYHLDLL+V++ I++NSILGIPWFVAATVLSINHV+SLKKESE +APGERPV+LGCREQRVTG +IFL IGLSVF+T LL RIPMAVLYG+FLFMG++SL GVQ++QRI L  MP KYQPDY +LR+VPLRRVH+FT IQ+  L +LWVIK+++ ++I FPIMVLA+CF+RK L+++FT +ELKWLDDI+P  K   +  N   ++   S +++K    +     S  ++ +  +  INI+EE+ KT+IW+QLSGG      K++ + K + ++      K                 D ES D G          S +   +PL  D               +  SG D  +  H ++ P+I +NPPS   SPE  H+N
Sbjct:    7 LADEPVVDSGARYHASEPSQDEIAGHRSKPTMLIGL---PSTEGGAATSMLHGLSSAGSSSHRHRRRRKRVTSQDRETDPSVPPADPSEYVMFLLGECDGDEEQPHHLFCELDELWNDLSGSGETEWREAARWIKFEEDVEENGERWSKPHVATLSLFSLFELRNCLATGVMMLNLEAFTMEQIADLTLNILVSEGRVPPDLRESLTELLLRRHVHLHERHRPKLSTRAASNIPLIRSLADIGKRYSSKEVDKEITSQPSLAKISTYGGMDTLDPALAAHVAAHAQASGPSEV---MSGS---LQGKYDLHFLKKVPPGSETSNILVGETTFLPAPITVFIRLREAVLLGDLTEVPVPTRFLFIHLGVLGHAAKYREIGRSMGVLMSDDVFHDVAYKAKSRADFLAGLDEFLSAATVLPPGEWDPSIRIEPPPSIPSQDSRKTGTSPNGNQASGQNAATAPVTQTDSVNVMEQLTAGGDRLAGLCLAAVGSATLLTQQTEDKSKGEVVKSVGSRPELVSLEALGGTGPDDSPGGHGNDPALQRTGIIFGGLARDIRRRAPHYLSDFTDALHVQCCASFIFLYFACLTPIITFGGLLSQATGGYLGTIESILSGAVVGILYSLFSGQPLTIMGSTGPVLIFEGIVYRMCQRLTWSYLSFRLWIGFWVSIMLLIMVALDLSALVKYITRFTEESFATLIALIFIIEALKKIYAVSKYYNVNLGWSPEALPHHNCTCAPPENSTDYDVL-------SAMYTEHPLVDVPLITSNNTQICISAADVDEAQFVSMTIDWNNISAGRFSWDSLQFRKVCTFLNGTWTGADCVPFYVPDVFFLSCILFIFTFAIAVYLKSMRTSLFFPARVRATISDFSVVIAIALTTLTDFFLGLHTPKLEVPHEFSPTVGYRRRGWIIPAFNGNPWWSALVALGPALVATILIFMDQQITAVIVNRRENKLRKGAGYHLDLLLVSVTIMINSILGIPWFVAATVLSINHVLSLKKESEASAPGERPVYLGCREQRVTGVLIFLFIGLSVFMTSLLGRIPMAVLYGIFLFMGISSLAGVQMIQRIGLILMPIKYQPDYSYLRHVPLRRVHMFTAIQVTCLAMLWVIKSVDAVAILFPIMVLAMCFIRKALDFIFTQDELKWLDDILPGSKAKNRPRNVYRVKS--SNDVLK---DDRHLLGSGVQLEQIPEKRINIAEEVAKTSIWRQLSGGNVKDTLKSQTKTKSKDSSKRGRRRKTRDSVNADGPNPKILGVDQESVDDGGELKMKPVFFSIDPLGRPLSKDPLAERSTPNAPWDVGNDSSGHDVVDSSHILSMPQITINPPSTHGSPETTHRN 1325          
BLAST of slc4a-1 vs. TrEMBL
Match: A0A074YZZ7 (Anion exchange protein OS=Opisthorchis viverrini OX=6198 GN=T265_11066 PE=3 SV=1)

HSP 1 Score: 1177.54 bits (3045), Expect = 0.000e+0
Identity = 641/1215 (52.76%), Postives = 814/1215 (67.00%), Query Frame = 2
Query:  119 VGDEPILDRGFQFTHYHPSEDEIEDHRSQRALYIGVHMPPDXXXXXXXXXXXXXXXXXXXXXDKKDYLTEIAEDDTEK-----ATDPSQHVMFLLGE-DEDEET-HNLFCEMDEL--RLDDEGEPEWKETARWIKFEEDVEEGGERWSKPHVASLSLYSLFEVRNCITSAVNMFNVEANNFETIIEIILNKIVSEKKISPDQREKVKEMLQRKHVHLHERRHK--SNAKGSQLPLIRSLADIGKKYSSKEVDKVQLQRRNSDYPTKFTRFDANXXXXXXXXXXXXXYVDKNRIDVDQCGSDNLASQKFDLHFFKKIPLGAETSNIMVGETDFLNQMVVVFIRLKEAVILGELTEVPVPTRFVFVMLGPQGSAVKNHEIGRSMATLMSDDVFHDVAYKARNLDDLLAGIDEFLSNCTVLPPAEWDPSIRIEPPKSGPI--ARKVPSMPNGAQA--------------------LLTASGDGRXXXXXXXXXXXXXXASVVNKLQPVEEESHA--------------------------------DPTLRRTGRLFGGLIEDVKRKAPFYLSDFKDAIHVQCFASFFFLYFACLTPIITFGGLLVQATGGYLGAIESILSGTIVGVVYSLFSGQPLTIMGSTGPVLVFESIVYNICERMRWDYLPFRLWIGVWIAAYLFLMVAFDLSALVRYITRFTEESFAALIALIFMVEAFKKLFLIVDYYPIDTRWNIDMIKNRTCECF-PRNATAMDAFFQKNNKPSNVYMPPML---YPVPLNSSVID----IVNNIDWQNISNYHFTWDYKKYRLICTKWGGIWTGSGCGNYFIPDVFFFSCLLFIGTFVLSYGLKMMRNAQFFPNWVRSLISDFAVMIAISSMTLLDWSLGFHTPKLNVPAKFEPTLGYKMRGWVIPALGKNPWWTIIIAMGPALLAVILIFMDQQITAVIVNRKENKLKKGSGYHXXXXXXXXXXXXXXXXGIPWFVAATVLSINHVMSLKKESENTAPGERPVFLGCREQRVTGTIIFLVIGLSVFLTPLLKRIPMAVLYGVFLFMGVASLKGVQLMQRISLFFMPAKYQPDYIFLRYVPLRRVHXXXXXXXXXXXXXXXXXXXNVMSICFPIMVLALCFVRKGLEYLFTYNELKWLDDIMPNHKKPPQDDNENDIEKCGSTELIKMTETNLEFNSSTNKVIRSNDSGINISEEMGKTAIWKQLSGG 3544
            + DEP++D G ++    PS+DEI  HRS+  + IG+   P                +    H  +     +   D E        DPS++VMFLLGE D DEE  H+LFCE+DEL   L   GE EW+E ARWIKFEEDVEE GERWSKPHVA+L L+SLFE+RNC+ + V M N+EA   E I ++ LN +VSE ++ PD RE + E+L R+HVHLHER     S    S +PLIRSLADIGK+YSSKEVDK    + +    + +   D+     +   ++ +     + +     GS      K+DLHF KK+P G+ETSNI+VGET FL   + VFIRL+EAV+LG+LTEVPVPTRF+F+ LG  G A K  EIGRSM  LMSDDVFHDVAYKA++  D LAG+DEFLS  TVLPP EWDPSIRIEPP S P   +RK  + PNG QA                     LTA GD                 S     Q  EE+S                                  DP L+RTG +FGGL  D++R+AP YLSDF DA+HVQC ASF FLYFACLTPIITFGGLL QATGGYLG IESILSG +VG++YSLFSGQPLTIMGSTGPVL+FE IVY +C+R+ W YL FRLWIG W++  L +MVA DLSALV+YITRFTEESFA LIALIF++EA KK++ +  YY ++  W+ + + +  C C  P N+T  D       K   V +P +      + ++++ +D    +   IDW NIS   F+WD  ++R +CT   G WTG+ C  +++PDVFF SC+LFI TF ++  LK MR + FFP  VR+ ISDF+V+IAI+  TL D+ LG HTPKL VP +F PT+GY+ RGW+IPA   NPWW+ ++A+GPAL+A ILIFMDQQITAVIVNR+ENKL KG+GYHLDLL+V++ I++NSILGIPWFVAATVLSINHV+SLKKESE +APGERPV+LGCREQRVTG +IFL IGLSVF+T LL RIPMAVLYG+FLFMG++SL GVQ++QRI L FMP KYQPDY +LR+VPLRRVH+FT IQ+  LV+LWVIK+++ ++I FPIMVLA+CF+RK L+++FT +ELKWLDDI+P +K   +  N   +    S +++K    +     S  ++ +  +  INI+EE+ KT+IW+QLSGG
Sbjct:    7 LADEPVVDSGARYHASEPSQDEIAGHRSKPTMLIGL---PSTEGGAATSTLHGLSSAGSSSHRHRRRRKRVTSQDRETDPSAPPADPSEYVMFLLGECDGDEEQPHHLFCELDELWNDLSGSGETEWREAARWIKFEEDVEENGERWSKPHVATLPLFSLFELRNCLATGVMMLNLEAFTMEQIADLTLNILVSEGRVPPDLRESLTELLLRRHVHLHERHRPKLSTRAASNIPLIRSLADIGKRYSSKEVDKEITSQTSLAKISTYGGMDSLDPGLAAHVAAHAQASGPSEV---MSGS---LQGKYDLHFLKKVPPGSETSNILVGETTFLPAPITVFIRLREAVLLGDLTEVPVPTRFLFIHLGVLGHAAKYREIGRSMGVLMSDDVFHDVAYKAKSRADFLAGLDEFLSAATVLPPGEWDPSIRIEPPASIPSQDSRKTGTSPNGNQASGQNATTVPVTQTDSVNVVEQLTAGGD------RLAGLCLAAVGSATLLTQQTEEKSKGEVVKSVGSRPELVSLEALGGTGADDAPGGHGNDPALQRTGIIFGGLARDIRRRAPHYLSDFTDALHVQCCASFIFLYFACLTPIITFGGLLSQATGGYLGTIESILSGAVVGILYSLFSGQPLTIMGSTGPVLIFEGIVYRMCQRLVWSYLSFRLWIGFWVSLMLLIMVALDLSALVKYITRFTEESFATLIALIFIIEALKKIYAVSKYYKVNLGWSPEALPHHNCTCAPPENSTDYDVLSAMYTKHPLVDVPLITSNNTQICISAADVDEAQFVSMTIDWNNISAGRFSWDSLQFRKVCTFLNGTWTGADCVPFYVPDVFFLSCILFIFTFAIAVYLKSMRTSLFFPARVRATISDFSVVIAIALTTLTDFFLGLHTPKLEVPHEFSPTVGYRRRGWIIPAFNGNPWWSALVALGPALVATILIFMDQQITAVIVNRRENKLIKGAGYHLDLLLVSVTIMINSILGIPWFVAATVLSINHVLSLKKESEASAPGERPVYLGCREQRVTGVLIFLFIGLSVFMTSLLGRIPMAVLYGIFLFMGISSLAGVQMIQRIGLIFMPIKYQPDYSYLRHVPLRRVHMFTAIQVTCLVMLWVIKSVDAVAILFPIMVLAMCFIRKALDFIFTQDELKWLDDILPGNKAKNRPRNVYRVRS--SNDVLK---DDRHLLGSGLQLEQIPEKRINIAEEVAKTSIWRQLSGG 1201          
BLAST of slc4a-1 vs. TrEMBL
Match: A0A419PX98 (Anion exchange protein (Fragment) OS=Clonorchis sinensis OX=79923 GN=Slc4a4 PE=3 SV=1)

HSP 1 Score: 1167.91 bits (3020), Expect = 0.000e+0
Identity = 656/1262 (51.98%), Postives = 830/1262 (65.77%), Query Frame = 2
Query:  338 DDTEKATDPSQHVMFLLGE-DEDEET-HNLFCEMDEL--RLDDEGEPEWKETARWIKFEEDVEEGGERWSKPHVASLSLYSLFEVRNCITSAVNMFNVEANNFETIIEIILNKIVSEKKISPDQREKVKEMLQRKHVHLHERRHK--SNAKGSQLPLIRSLADIGKKYSSKEVDKVQLQRRNSDYPTKFTRFDANXXXXXXXXXXXXXYVDKNRIDVDQCGSDNLASQKFDLHFFKKIPLGAETSNIMVGETDFLNQMVVVFIRLKEAVILGELTEVPVPTRFVFVMLGPQGSAVKNHEIGRSMATLMSDDVFHDVAYKARNLDDLLAGIDEFLSNCTVLPPAEWDPSIRIEPPKSGPI--ARKVPSMPNGAQA--------------------LLTASGDGRXXXXXXXXXXXXXXA-------------SVVNKLQPVEEESHA-------------DPTLRRTGRLFGGLIEDVKRKAPFYLSDFKDAIHVQCFASFFFLYFACLTPIITFGGLLVQATGGYLGAIESILSGTIVGVVYSLFSGQPLTIMGSTGPVLVFESIVYNICERMRWDYLPFRLWIGVWIAAYLFLMVAFDLSALVRYITRFTEESFAALIALIFMVEAFKKLFLIVDYYPIDTRWNIDMIKNRTCECF-PRNATAMDAFFQKNNKPSNVYMPPMLYPVPL---NSSVIDIVN-----------NIDWQNISNYHFTWDYKKYRLICTKWGGIWTGSGCGNYFIPDVFFFSCLLFIGTFVLSYGLKMMRNAQFFPNWVRSLISDFAVMIAISSMTLLDWSLGFHTPKLNVPAKFEPTLGYKMRGWVIPALGKNPWWTIIIAMGPALLAVILIFMDQQITAVIVNRKENKLKKGSGYHXXXXXXXXXXXXXXXXGIPWFVAATVLSINHVMSLKKESENTAPGERPVFLGCREQRVTGTIIFLVIGLSVFLTPLLKRIPMAVLYGVFLFMGVASLKGVQLMQRISLFFMPAKYQPDYIFLRYVPLRRVHXXXXXXXXXXXXXXXXXXXNVMSICFPIMVLALCFVRKGLEYLFTYNELKWLDDIMPNHKKPPQDDNENDIEKCGSTELIKMTETNLEFNSSTNKVIRSNDSGINISEEMGKTAIWKQLSGGTXXXXXXXXXXXXXXXXXXDRSGNK-----------------DMESGDQGN---------SDNSHVQPLLND---------------SRESGRD--NKHHYMTTPEIVVNPPSARESPELKHQN 3787
            D +    DPS++VMFLLGE D DEE  H+LFCE+DEL   L   GE EW+E ARWIKFEEDVEE GERWSKPHVA+LSL+SLFE+RNC+ + V M N+EA   E I ++ LN +VSE ++ PD RE + E+L R+HVHLHER     S    S +PLIRSLADIGK+YSSKEVDK    + +    + +   D      +   ++ +     + +     GS      K+DLHF KK+P G+ETSNI+VGET FL   + VFIRL+EAV+LG+LTEVPVPTRF+F+ LG  G A K  EIGRSM  LMSDDVFHDVAYKA++  D LAG+DEFLS  TVLPP EWDPSIRIEPP S P   +RK  + PNG QA                     LTA GD   G       S T                SV ++ + V  E+               DP L+RTG +FGGL  D++R+AP YLSDF DA+HVQC ASF FLYFACLTPIITFGGLL QATGGYLG IESILSG +VG++YSLFSGQPLTIMGSTGPVL+FE IVY +C+R+ W YL FRLWIG W++  L +MVA DLSALV+YITRFTEESFA LIALIF++EA KK++ +  YY ++  W+ + + +  C C  P N+T  D         S +Y    L  VPL   N++ I I              IDW NIS   F+WD  ++R +CT   G WTG+ C  +++PDVFF SC+LFI TF ++  LK MR + FFP  VR+ ISDF+V+IAI+  TL D+ LG HTPKL VP +F PT+GY+ RGW+IPA   NPWW+ ++A+GPAL+A ILIFMDQQITAVIVNR+ENKL+KG+GYHLDLL+V++ I++NSILGIPWFVAATVLSINHV+SLKKESE +APGERPV+LGCREQRVTG +IFL IGLSVF+T LL RIPMAVLYG+FLFMG++SL GVQ++QRI L  MP KYQPDY +LR+VPLRRVH+FT IQ+  L +LWVIK+++ ++I FPIMVLA+CF+RK L+++FT +ELKWLDDI+P  K   +  N   ++   S +++K    +     S  ++ +  +  INI+EE+ KT+IW+QLSGG      K++ + K + ++      K                 D ES D G          S +   +PL  D               +  SG D  +  H ++ P+I +NPPS   SPE  H+N
Sbjct:   51 DPSVPPADPSEYVMFLLGECDGDEEQPHHLFCELDELWNDLSGSGETEWREAARWIKFEEDVEENGERWSKPHVATLSLFSLFELRNCLATGVMMLNLEAFTMEQIADLTLNILVSEGRVPPDLRESLTELLLRRHVHLHERHRPKLSTRAASNIPLIRSLADIGKRYSSKEVDKEITSQPSLAKISTYGGMDTLDPALAAHVAAHAQASGPSEV---MSGS---LQGKYDLHFLKKVPPGSETSNILVGETTFLPAPITVFIRLREAVLLGDLTEVPVPTRFLFIHLGVLGHAAKYREIGRSMGVLMSDDVFHDVAYKAKSRADFLAGLDEFLSAATVLPPGEWDPSIRIEPPPSIPSQDSRKTGTSPNGNQASGQNAATAPVTQTDSVNVMEQLTAGGDRLAGLCLAAVGSATLLTQQTEDKSKGEVVKSVGSRPELVSLEALGGTGPDDSPGGHGNDPALQRTGIIFGGLARDIRRRAPHYLSDFTDALHVQCCASFIFLYFACLTPIITFGGLLSQATGGYLGTIESILSGAVVGILYSLFSGQPLTIMGSTGPVLIFEGIVYRMCQRLTWSYLSFRLWIGFWVSIMLLIMVALDLSALVKYITRFTEESFATLIALIFIIEALKKIYAVSKYYNVNLGWSPEALPHHNCTCAPPENSTDYDVL-------SAMYTEHPLVDVPLITSNNTQICISAADVDEAQFVSMTIDWNNISAGRFSWDSLQFRKVCTFLNGTWTGADCVPFYVPDVFFLSCILFIFTFAIAVYLKSMRTSLFFPARVRATISDFSVVIAIALTTLTDFFLGLHTPKLEVPHEFSPTVGYRRRGWIIPAFNGNPWWSALVALGPALVATILIFMDQQITAVIVNRRENKLRKGAGYHLDLLLVSVTIMINSILGIPWFVAATVLSINHVLSLKKESEASAPGERPVYLGCREQRVTGVLIFLFIGLSVFMTSLLGRIPMAVLYGIFLFMGISSLAGVQMIQRIGLILMPIKYQPDYSYLRHVPLRRVHMFTAIQVTCLAMLWVIKSVDAVAILFPIMVLAMCFIRKALDFIFTQDELKWLDDILPGSKAKNRPRNVYRVKS--SNDVLK---DDRHLLGSGVQLEQIPEKRINIAEEVAKTSIWRQLSGGNVKDTLKSQTKTKSKDSSKRGRRRKTRDSVNADGPNPKILGVDQESVDDGGELKMKPVFFSIDPLGRPLSKDPLAERSTPNAPWDVGNDSSGHDVVDSSHILSMPQITINPPSTHGSPETTHRN 1294          
BLAST of slc4a-1 vs. Ensembl Cavefish
Match: slc4a8 (solute carrier family 4 member 8 [Source:ZFIN;Acc:ZDB-GENE-131119-88])

HSP 1 Score: 931.784 bits (2407), Expect = 0.000e+0
Identity = 542/1156 (46.89%), Postives = 734/1156 (63.49%), Query Frame = 2
Query:  125 DEPILDRG--FQFTHYHPSEDEIEDHRSQRALYIGVHMP---PDXXXXXXXXXXXXXXXXXXXXXDKKDYLTEIAEDDTEKATDPSQHVMFLLGEDEDEE--THNLFCEMDELRLDDEGEPEWKETARWIKFEEDVEEGGERWSKPHVASLSLYSLFEVRNCITSAVNMFNVEANNFETIIEIILNKIVSEKKISPDQREKVKEMLQRKHVHLHERRHKSNAKGSQLPLIRSLADIGKKYSSKEVDKVQLQRRNSDYPTKFTRFDANXXXXXXXXXXXXXYVDKNRIDVDQCGSDNLASQKFDLHFFKKIPLGAETSNIMVGETDFLNQMVVVFIRLKEAVILGELTEVPVPTRFVFVMLGPQGSAVKNHEIGRSMATLMSDDVFHDVAYKARNLDDLLAGIDEFLSNCTVLPPAEWDPSIRIEPPKSGPIA--RKVPSMPNGAQALLTASGDGRXXXXXXXXXXXXXXASVVNKLQPVEEESHAD---PTLRRTGRLFGGLIEDVKRKAPFYLSDFKDAIHVQCFASFFFLYFACLTPIITFGGLLVQATGGYLGAIESILSGTIVGVVYSLFSGQPLTIMGSTGPVLVFESIVYNICERMRWDYLPFRLWIGVWIAAYLFLMVAFDLSALVRYITRFTEESFAALIALIFMVEAFKKLFLIVDYYPIDTRWNIDMIKNRTCECF----PRNATAMDAFFQKNNKPSNVYMPPMLYPVPLNSSVIDIVNNIDWQNISNYHFTWDYKKYRLICTKWGGIWTGSGCGNY--FIPDVFFFSCLLFIGTFVLSYGLKMMRNAQFFPNWVRSLISDFAVMIAISSMTLLDWSLGFHTPKLNVPAKFEPTLGYKMRGWVIPALGKNPWWTIIIAMGPALLAVILIFMDQQITAVIVNRKENKLKKGSGYHXXXXXXXXXXXXXXXXGIPWFVAATVLSINHVMSLKKESENTAPGERPVFLGCREQRVTGTIIFLVIGLSVFLTPLLKRIPMAVLYGVFLFMGVASLKGVQLMQRISLFFMPAKYQPDYIFLRYVPLRRVHXXXXXXXXXXXXXXXXXXXNVMSICFPIMVLALCFVRKGLEYLFTYNELKWLDDIMPNHKKPPQDDNENDIEKCGSTELIKMTETNLEFNSSTNKVIRSNDSGINISEEMGKTAIWKQLS 3538
            +E ++D+G      + H  ++E+E HR+   LY+GV MP   P   H+ ++ R+R   ++     + ++               PSQ V F+LG +EDEE   H+LF E+DE+ + D  + EWKETARW+KFEEDVE+GGERWSKP+VA+LSL+SLFE+R+C+ +   + ++ A++ E I +++L+   +  ++    R KV+E L ++H H  +++     + + LP+++SL + G+K S  ++DK          P      +                 D  ++D+           K D HF KKIP GAE SN++VGE DFL + +V F+RL  AV+L  LTEVP+PTRF+F++LGP G A + HEIGRSMAT+M+D++FHDVAYKA+N  DLLAGIDEFL   TVLPP EWDPSIRIEPPK+ P    RK+P +PNG                                + PVEEE H +   P L+RTGRLFGGLI DVKRKAPFYLSDFKD I++QC ASF FLY AC++P+ITFGGLL +AT G + AIES+   ++ GV YSLF+GQPLTI+GSTGPVLVFE I++  C+     YL  R  IG+W A   FL+VA D S+LV YITRFTEE+FA+LI LIF+ EA +KL  + + YPI+   ++D +    C+C     P N T M  + ++N   S V                       W N++              C    G + G+ CG++  + PDV F+S +LF  TF LS  LK  + +++FP  VRS+ISDFAV + I  M L+D+++G  + KL VP+KF+PT     RGW+I  +G+NPWWT++ A  PALL  ILIFMDQQITAVI+NRKE+KL KG GYHLDLL+V +++ V SI+G+PWFVAATVLSI+HV SLK ESE+ APGE+P FLG REQR+TG +IFL++G SVF+T  L+ IPM VLYGVFL+MG +SLKG+Q   R+ LF MPAK+QPD+I+LR+VPLR+VHLFT+ Q+  LVLLWVIKT    +I FP+MVLAL F+RK L++ FT  EL +LDDIMP  KK   DD    +E+   +       + +   +S +    ++ S INIS+EM KT +WK LS
Sbjct:   20 EEVVVDQGGTSSVLNIHYEKEELEGHRT---LYVGVRMPMGRPSHRHRSSKHRKRERVRAGSLAPEGENTDDTTTT----SHDTPSQRVQFILGTEEDEEHVAHDLFTELDEICVKDGKDAEWKETARWLKFEEDVEDGGERWSKPYVATLSLHSLFELRSCLINGTVLLDMRADSIEEIADMVLDHQEAAHELDDSVRVKVREALLKRHHHQSDKK-----RSNLLPMVKSLTESGRKQSEPQMDKSGPATSPQPPPVSADVKNGTGQ-------------DNGQVDL----------SKVDTHFMKKIPTGAEASNVLVGELDFLERPIVAFVRLSPAVLLTGLTEVPIPTRFMFILLGPDGKAQQYHEIGRSMATIMTDEIFHDVAYKAKNRSDLLAGIDEFLDQVTVLPPGEWDPSIRIEPPKTVPSQEKRKMPGVPNGT-------------------------------VVPVEEEPHGEHHGPELQRTGRLFGGLILDVKRKAPFYLSDFKDGINLQCVASFLFLYCACMSPVITFGGLLGEATEGRISAIESLFGASMTGVAYSLFAGQPLTILGSTGPVLVFEKILFKFCKDYDLSYLSLRACIGLWTAFLCFLLVATDASSLVCYITRFTEEAFASLICLIFIYEALEKLVHLGELYPINKHSDLDKLTLTYCKCAEPDNPGNKTLM-MWSERNITASGV----------------------SWSNLTVKE-----------CLDLHGHFVGTACGHHGPYTPDVLFWSAILFFSTFFLSTFLKQFKTSRYFPTKVRSMISDFAVFLTIVFMVLIDYAIGVPSQKLQVPSKFKPT--RDDRGWLINPIGRNPWWTVLAASVPALLCTILIFMDQQITAVIINRKEHKLLKGCGYHLDLLMVGVMLAVCSIMGLPWFVAATVLSISHVNSLKLESESAAPGEQPRFLGIREQRLTGLVIFLLMGCSVFMTGALQFIPMPVLYGVFLYMGASSLKGIQFFDRLKLFGMPAKHQPDFIYLRHVPLRKVHLFTLTQLTCLVLLWVIKTSPA-AIVFPMMVLALVFIRKLLDFCFTKRELSYLDDIMPESKKKKLDDASKTVEEVLLSVTAHYLNSTIIKQNSLHLNCVTDPSDINISDEMSKTTVWKSLS 1072          
BLAST of slc4a-1 vs. Ensembl Cavefish
Match: slc4a10b (solute carrier family 4 member 10 [Source:NCBI gene;Acc:103025302])

HSP 1 Score: 926.006 bits (2392), Expect = 0.000e+0
Identity = 538/1159 (46.42%), Postives = 733/1159 (63.24%), Query Frame = 2
Query:  125 DEPILDRGFQFTHYHPS--EDEIEDHRSQRALYIGVHMPPDXXXXXXXXXXXXXXXXXXXXXDKKDYLTEIAEDDTEKATD-PSQHVMFLLG-EDEDEE--THNLFCEMDELRLDDEGEPEWKETARWIKFEEDVEEGGERWSKPHVASLSLYSLFEVRNCITSAVNMFNVEANNFETIIEIILNKIVSEKKISPDQREKVKEMLQRKHVHLHERRHKSNAKGSQLPLIRSLADIGKKYS-SKEVDKVQLQRRNSDYPTKFTRFDANXXXXXXXXXXXXXYVDKNRIDVDQCGSDNLASQKFDLHFFKKIPLGAETSNIMVGETDFLNQMVVVFIRLKEAVILGELTEVPVPTRFVFVMLGPQGSAVKNHEIGRSMATLMSDDVFHDVAYKARNLDDLLAGIDEFLSNCTVLPPAEWDPSIRIEPPKSGPIA--RKVPSMPNGAQALLTASGDGRXXXXXXXXXXXXXXASVVNKLQPVEEESHADPTLRRTGRLFGGLIEDVKRKAPFYLSDFKDAIHVQCFASFFFLYFACLTPIITFGGLLVQATGGYLGAIESILSGTIVGVVYSLFSGQPLTIMGSTGPVLVFESIVYNICERMRWDYLPFRLWIGVWIAAYLFLMVAFDLSALVRYITRFTEESFAALIALIFMVEAFKKLFLIVDYYPIDTRWNIDMIKNRTCECF----PRNATAMDAFFQKNNKPSNVYMPPMLYPVPLNSSVIDIVNNIDWQNISNYHFTWDYKKYRLICTKWGGIWTGSGCGNY--FIPDVFFFSCLLFIGTFVLSYGLKMMRNAQFFPNWVRSLISDFAVMIAISSMTLLDWSLGFHTPKLNVPAKFEPTLGYKMRGWVIPALGKNPWWTIIIAMGPALLAVILIFMDQQITAVIVNRKENKLKKGSGYHXXXXXXXXXXXXXXXXGIPWFVAATVLSINHVMSLKKESENTAPGERPVFLGCREQRVTGTIIFLVIGLSVFLTPLLKRIPMAVLYGVFLFMGVASLKGVQLMQRISLFFMPAKYQPDYIFLRYVPLRRVHXXXXXXXXXXXXXXXXXXXNVMSICFPIMVLALCFVRKGLEYLFTYNELKWLDDIMPNHKKPPQDDNENDIEKCGSTELIKMTETNLEFNSSTNKVIRSNDSGINISEEMGKTAI---WKQLSGGT 3547
            +E ++DRG   +    +  ++E+E H++   LYIGVH+P  R  +   +      + +  + D     + + +     A D PSQ V FLLG ED+DEE   H+LF E+DE+ L D  + EW+ETARW+KFEEDVE+GGERWSKP+VA+L+L+SLFE+R+CI +   M ++ A++ E I +++L++     ++  + R+K+++ L ++H H ++++       +++P++RS ADIGKK S S  +DK                 +     P          V +    VD          K DLHF KKIP GAE SNI+VGE +FL + VV FIRL  AV+L  L EVP+ TRF+F++LGP G   + HEIGRS+ATLM+D+VFHDVAYKA++ +DL+AGIDEFL   TVLPP EWDPSIRIEPPK+ P    RK+P++PNG  A                              +  E   H  P L+RTGRLFGG   D+KRKAP YLSD+ DA+ +QC ASF FLY AC++P+ITFGGLL +AT G + AIES+   ++ G+ YSLF+GQPLTI+GSTGPVLVFE I++  C+     YL  R  IG+W A    L+VA D S+LV YITRFTEE+FA+LI +IF+ EA +KL  + + YPI+   N+D +   +C C     P NAT +  + Q N   S +Y                      W+ +               C +  G++ GS CG +  +IPDV F+S +LF  T  +S  LK  + +++FP  VR++ISDFAV   I +M L+D++LG  +PKL VP+KF+PT     RGW I  LG NPWWT II + PALL  ILIFMDQQITAVI+NRKE+KLKKG GYHLDL VVA+++ V S++G+PWFVAATVLSI+HV SLK ESE++APGE+P FLG REQR TG +IFL++G SVF+T +LK IPM VLYGVFL+MG +SL+G+Q   R+ LF MPAK+QPD+I+LR+VPLR+VHLFTI+Q+  L+LLWVIKT    +I FP+MVLAL F+RK L++ FT  EL WLDD+MP  KK   +D E + E+    E   + +  LE +       + + S +NI++EM K +    WK ++  T
Sbjct:   66 EEAVVDRGGTRSMLKANVEQEELEGHKT---LYIGVHVPLGRRTRRRHRHHGHRHRKRSRERD-----SGVGDGRESPAYDTPSQRVQFLLGTEDDDEEHIPHDLFTELDEICLRDGEDSEWRETARWLKFEEDVEDGGERWSKPYVATLTLHSLFELRSCIINGTVMLDMRASSLEEIADMVLDQQEGLDELGDEVRKKIRQALLKQHHHQNQKK-----LANRIPIVRSFADIGKKQSESNSMDK-----------------NGQMIPPQPCAPELKPEVSRENSSVD--------FSKIDLHFMKKIPAGAEASNILVGELEFLEKPVVAFIRLSPAVLLNGLAEVPITTRFLFILLGPLGKGPQYHEIGRSIATLMTDEVFHDVAYKAKDRNDLVAGIDEFLDQVTVLPPGEWDPSIRIEPPKNVPSQEKRKIPAVPNGELA------------------------------ETEEHGGHGGPELQRTGRLFGGFFLDIKRKAPHYLSDYTDALSLQCVASFLFLYCACMSPVITFGGLLGEATEGRISAIESLFGASMTGIAYSLFAGQPLTILGSTGPVLVFEKILFKFCKEYGLSYLSLRTCIGLWTAFLCILLVATDASSLVCYITRFTEEAFASLICIIFIYEALEKLIHLGETYPINMNNNLDKLTTYSCACIEPVNPSNAT-LQYWEQNNITASEIY----------------------WEALEVED-----------CIEKKGVFVGSACGPHGPYIPDVLFWSVVLFFSTVAMSAFLKEFKTSRYFPTKVRAIISDFAVFFTILTMVLVDYALGVPSPKLQVPSKFKPT--RDDRGWFINPLGPNPWWTCIITVIPALLCTILIFMDQQITAVIINRKEHKLKKGCGYHLDLFVVAVMLGVCSLMGLPWFVAATVLSISHVNSLKLESESSAPGEQPKFLGIREQRFTGLMIFLLMGCSVFMTSVLKFIPMPVLYGVFLYMGASSLRGIQFFDRLRLFGMPAKHQPDFIYLRHVPLRKVHLFTIVQLSCLILLWVIKTSRA-AIVFPMMVLALVFIRKLLDFFFTKRELSWLDDLMPESKKKRLEDAEKEEEQSILAEEEGVVQVPLEAH------YKDDPSSVNITDEMSKASFGNTWKTMNSDT 1113          
BLAST of slc4a-1 vs. Ensembl Cavefish
Match: slc4a10a (sodium-driven chloride bicarbonate exchanger-like [Source:NCBI gene;Acc:103033693])

HSP 1 Score: 924.85 bits (2389), Expect = 0.000e+0
Identity = 537/1156 (46.45%), Postives = 736/1156 (63.67%), Query Frame = 2
Query:  125 DEPILDRGFQFTHYHPS--EDEIEDHRSQRALYIGVHMPPDXXXXXXXXXXXXXXXXXXXXXDKKDYLTEIAEDDTEKATDPSQHVMFLLG-EDEDEE--THNLFCEMDELRLDDEGEPEWKETARWIKFEEDVEEGGERWSKPHVASLSLYSLFEVRNCITSAVNMFNVEANNFETIIEIILNKIVSEKKISPDQREKVKEMLQRKHVHLHERRHKSNAKGSQLPLIRSLADIGKKYSS-KEVDK-VQLQRRNSDYPTKFTRFDANXXXXXXXXXXXXXYVDKNRIDVDQCGSDNLASQKFDLHFFKKIPLGAETSNIMVGETDFLNQMVVVFIRLKEAVILGELTEVPVPTRFVFVMLGPQGSAVKNHEIGRSMATLMSDDVFHDVAYKARNLDDLLAGIDEFLSNCTVLPPAEWDPSIRIEPPKSGPIA--RKVPSMPNGAQALLTASGDGRXXXXXXXXXXXXXXASVVNKLQPVEEESHADPTLRRTGRLFGGLIEDVKRKAPFYLSDFKDAIHVQCFASFFFLYFACLTPIITFGGLLVQATGGYLGAIESILSGTIVGVVYSLFSGQPLTIMGSTGPVLVFESIVYNICERMRWDYLPFRLWIGVWIAAYLFLMVAFDLSALVRYITRFTEESFAALIALIFMVEAFKKLFLIVDYYPIDTRWNIDMIKNRTCECF----PRNATAMDAFFQKNNKPSNVYMPPMLYPVPLNSSVIDIVNNIDWQNISNYHFTWDYKKYRLICTKWGGIWTGSGCGNY--FIPDVFFFSCLLFIGTFVLSYGLKMMRNAQFFPNWVRSLISDFAVMIAISSMTLLDWSLGFHTPKLNVPAKFEPTLGYKMRGWVIPALGKNPWWTIIIAMGPALLAVILIFMDQQITAVIVNRKENKLKKGSGYHXXXXXXXXXXXXXXXXGIPWFVAATVLSINHVMSLKKESENTAPGERPVFLGCREQRVTGTIIFLVIGLSVFLTPLLKRIPMAVLYGVFLFMGVASLKGVQLMQRISLFFMPAKYQPDYIFLRYVPLRRVHXXXXXXXXXXXXXXXXXXXNVMSICFPIMVLALCFVRKGLEYLFTYNELKWLDDIMPNHKKPPQDDNENDIEKCGSTELIKMTETNLEFNSSTNKVIRSNDSGINISEEMGKTA---IWKQLS 3538
            +E +LDRG   +  + +  ++E+E HR+   LYIGVH+P   + + + +R R H    + +  ++D  TE   +       PSQ V FLLG EDEDEE   H LF E+DE+ L +  + EWKETARW+KFEEDVE+GGERWSKP+VA+LSL+SLFE+R+CI + + M ++ AN+ E I +++L++  +   +  + R+K++  L ++H H ++++       +++P++RS ADIGKK S    +DK  Q+    S  P   +R D +               + + +D            K DLHF KKIP GAE SNI+VGE +FL + VV F+RL  AV+L  L EVP+ TRF+F++LGP G   + HEIGRS+AT+M+D+VFHDVAYKA++  DL+AGIDEFL   TVLPP EWDP+IRIEPPK+ P    RK+P +PNG   L                                E   H  P L+RTG+ FGG   D+KRKAP YLSD+ DAI +QC ASF FLY AC++P+ITFGGLL +AT G + AIES+   ++ G+ YSLF+GQPLTI+GSTGPVLVFE I++  C+     YL  R+ IG+W A +  L+VA D S+LV YITRFTEE+FA+LI +IF+ EA +KL  + ++YP +   +++ +   +C C     P NAT    ++Q+ N  ++                      +DW  +       D K     C  + G + GS CG++  +IPDV F+S +LF  T  +S  LK  + +++FP  VR +ISDFAV I I +M  +D++LG  +PKL VP +F+PT     RGW+I  LG NPWWT II   PALL  ILIFMDQQITAVI+NRKE+KLKKG GYHLDL VV +++ V S++G+PWFVAATVLSI+HV SLK ESE +APGE+P FLG REQR TG +IFL++G SVF+T +LK IPM VLYGVFL+MG +SL+G+Q   R+ LF MPAK+QPD+I+LR+VPLR+VHLFTI+Q+  L +LW+IKT    +I FP+MVLAL F+RK L++ FT  EL WLDD+MP  KK   +D + ++    +T L                V+R + S +NIS+EM KT+   +WK L+
Sbjct:   43 EEAVLDRGGTRSMLNTNFEKEELEGHRT---LYIGVHVP---LGRRSHRRHRHHGHRHRKRSRERDSGTEDGRESPSFMDTPSQRVQFLLGMEDEDEEHIPHALFTELDEICLREGEDAEWKETARWLKFEEDVEDGGERWSKPYVATLSLHSLFELRSCILNGIVMLDMRANSLEEIADMVLDQQETSIALGEEVRKKIRNALLKQHHHQNQKK-----LANRIPIVRSFADIGKKQSEPHSMDKNGQMVSPQSQPPCTESRSDGSR--------------ENSAVDF----------SKIDLHFMKKIPPGAEASNILVGELEFLEKPVVAFVRLSPAVLLNGLAEVPITTRFLFILLGPMGKGPQYHEIGRSIATIMTDEVFHDVAYKAKDRSDLVAGIDEFLDQVTVLPPGEWDPTIRIEPPKNVPSQEKRKIPPLPNGVTDLGEEG----------------------------EHGGHGGPELQRTGKFFGGFFMDIKRKAPHYLSDYTDAISLQCLASFLFLYCACMSPVITFGGLLGEATEGRISAIESLFGASMTGIAYSLFAGQPLTILGSTGPVLVFEKILFKFCKEYGLSYLSLRVCIGLWTAFFCLLLVATDASSLVCYITRFTEEAFASLICIIFIYEALEKLVHLGEHYPFNMHGDLNKLTQYSCVCTEPKDPSNATL--RYWQEKNITTS---------------------EVDWLGL-------DVKG----CMMYRGEFQGSACGHHGPYIPDVLFWSVILFFATVAMSSFLKEFKTSRYFPTKVRQIISDFAVFITIVTMVGIDFALGVPSPKLQVPNEFKPT--RDDRGWIISPLGPNPWWTTIITSIPALLCTILIFMDQQITAVIINRKEHKLKKGCGYHLDLFVVGVMLGVCSVMGLPWFVAATVLSISHVNSLKLESECSAPGEQPKFLGIREQRFTGLMIFLLMGCSVFMTSVLKFIPMPVLYGVFLYMGASSLRGIQFFDRLKLFGMPAKHQPDFIYLRHVPLRKVHLFTIVQLSCLAMLWIIKTSRA-AIVFPMMVLALVFIRKLLDFFFTKRELSWLDDLMPESKKKKLEDAQQEVPPVMNTVL------------CFCPVLRDDPSSVNISDEMTKTSFGNVWKSLN 1086          
BLAST of slc4a-1 vs. Ensembl Cavefish
Match: slc4a10b (solute carrier family 4 member 10 [Source:NCBI gene;Acc:103025302])

HSP 1 Score: 924.465 bits (2388), Expect = 0.000e+0
Identity = 541/1164 (46.48%), Postives = 735/1164 (63.14%), Query Frame = 2
Query:  113 ITVGDE-PILDRGFQFTHYHPS--EDEIEDHRSQRALYIGVHMPPDXXXXXXXXXXXXXXXXXXXXXDKKDYLTEIAEDDTEKATD-PSQHVMFLLG-EDEDEE--THNLFCEMDELRLDDEGEPEWKETARWIKFEEDVEEGGERWSKPHVASLSLYSLFEVRNCITSAVNMFNVEANNFETIIEIILNKIVSEKKISPDQREKVKEMLQRKHVHLHERRHKSNAKGSQLPLIRSLADIGKKYS-SKEVDKVQLQRRNSDYPTKFTRFDANXXXXXXXXXXXXXYVDKNRIDVDQCGSDNLASQKFDLHFFKKIPLGAETSNIMVGETDFLNQMVVVFIRLKEAVILGELTEVPVPTRFVFVMLGPQGSAVKNHEIGRSMATLMSDDVFHDVAYKARNLDDLLAGIDEFLSNCTVLPPAEWDPSIRIEPPKSGPIA--RKVPSMPNGAQALLTASGDGRXXXXXXXXXXXXXXASVVNKLQPVEEESHADPTLRRTGRLFGGLIEDVKRKAPFYLSDFKDAIHVQCFASFFFLYFACLTPIITFGGLLVQATGGYLGAIESILSGTIVGVVYSLFSGQPLTIMGSTGPVLVFESIVYNICERMRWDYLPFRLWIGVWIAAYLFLMVAFDLSALVRYITRFTEESFAALIALIFMVEAFKKLFLIVDYYPIDTRWNIDMIKNRTCECF----PRNATAMDAFFQKNNKPSNVYMPPMLYPVPLNSSVIDIVNNIDWQNISNYHFTWDYKKYRLICTKWGGIWTGSGCGNY--FIPDVFFFSCLLFIGTFVLSYGLKMMRNAQFFPNWVRSLISDFAVMIAISSMTLLDWSLGFHTPKLNVPAKFEPTLGYKMRGWVIPALGKNPWWTIIIAMGPALLAVILIFMDQQITAVIVNRKENKLKKGSGYHXXXXXXXXXXXXXXXXGIPWFVAATVLSINHVMSLKKESENTAPGERPVFLGCREQRVTGTIIFLVIGLSVFLTPLLKRIPMAVLYGVFLFMGVASLKGVQLMQRISLFFMPAKYQPDYIFLRYVPLRRVHXXXXXXXXXXXXXXXXXXXNVMSICFPIMVLALCFVRKGLEYLFTYNELKWLDDIMPNHKKPPQDDNENDIEKCGSTELIKMTETNLEFNSSTNKVIRSNDSGINISEEMGKTAI---WKQLSGGT 3547
            I  GDE  ++DRG   +    +  ++E+E H++   LYIGVH+P  R  +   +      + +  + D     + + +     A D PSQ V FLLG ED+DEE   H+LF E+DE+ L D  + EW+ETARW+KFEEDVE+GGERWSKP+VA+L+L+SLFE+R+CI +   M ++ A++ E I +++L++     ++  + R+K+++ L ++H H ++++       +++P++RS ADIGKK S S  +DK                 +     P          V +    VD          K DLHF KKIP GAE SNI+VGE +FL + VV FIRL  AV+L  L EVP+ TRF+F++LGP G   + HEIGRS+ATLM+D+VFHDVAYKA++ +DL+AGIDEFL   TVLPP EWDPSIRIEPPK+ P    RK+P++PNG  A                              +  E   H  P L+RTGRLFGG   D+KRKAP YLSD+ DA+ +QC ASF FLY AC++P+ITFGGLL +AT G + AIES+   ++ G+ YSLF+GQPLTI+GSTGPVLVFE I++  C+     YL  R  IG+W A    L+VA D S+LV YITRFTEE+FA+LI +IF+ EA +KL  + + YPI+   N+D +   +C C     P NAT +  + Q N   S +Y                      W+ +               C +  G++ GS CG +  +IPDV F+S +LF  T  +S  LK  + +++FP  VR++ISDFAV   I +M L+D++LG  +PKL VP+KF+PT     RGW I  LG NPWWT II + PALL  ILIFMDQQITAVI+NRKE+KLKKG GYHLDL VVA+++ V S++G+PWFVAATVLSI+HV SLK ESE++APGE+P FLG REQR TG +IFL++G SVF+T +LK IPM VLYGVFL+MG +SL+G+Q   R+ LF MPAK+QPD+I+LR+VPLR+VHLFTI+Q+  L+LLWVIKT    +I FP+MVLAL F+RK L++ FT  EL WLDD+MP  KK   +D E + E+    E   + +  LE +       + + S +NI++EM K +    WK ++  T
Sbjct:    9 ICRGDEEAVVDRGGTRSMLKANVEQEELEGHKT---LYIGVHVPLGRRTRRRHRHHGHRHRKRSRERD-----SGVGDGRESPAYDTPSQRVQFLLGTEDDDEEHIPHDLFTELDEICLRDGEDSEWRETARWLKFEEDVEDGGERWSKPYVATLTLHSLFELRSCIINGTVMLDMRASSLEEIADMVLDQQEGLDELGDEVRKKIRQALLKQHHHQNQKK-----LANRIPIVRSFADIGKKQSESNSMDK-----------------NGQMIPPQPCAPELKPEVSRENSSVD--------FSKIDLHFMKKIPAGAEASNILVGELEFLEKPVVAFIRLSPAVLLNGLAEVPITTRFLFILLGPLGKGPQYHEIGRSIATLMTDEVFHDVAYKAKDRNDLVAGIDEFLDQVTVLPPGEWDPSIRIEPPKNVPSQEKRKIPAVPNGELA------------------------------ETEEHGGHGGPELQRTGRLFGGFFLDIKRKAPHYLSDYTDALSLQCVASFLFLYCACMSPVITFGGLLGEATEGRISAIESLFGASMTGIAYSLFAGQPLTILGSTGPVLVFEKILFKFCKEYGLSYLSLRTCIGLWTAFLCILLVATDASSLVCYITRFTEEAFASLICIIFIYEALEKLIHLGETYPINMNNNLDKLTTYSCACIEPVNPSNAT-LQYWEQNNITASEIY----------------------WEALEVED-----------CIEKKGVFVGSACGPHGPYIPDVLFWSVVLFFSTVAMSAFLKEFKTSRYFPTKVRAIISDFAVFFTILTMVLVDYALGVPSPKLQVPSKFKPT--RDDRGWFINPLGPNPWWTCIITVIPALLCTILIFMDQQITAVIINRKEHKLKKGCGYHLDLFVVAVMLGVCSLMGLPWFVAATVLSISHVNSLKLESESSAPGEQPKFLGIREQRFTGLMIFLLMGCSVFMTSVLKFIPMPVLYGVFLYMGASSLRGIQFFDRLRLFGMPAKHQPDFIYLRHVPLRKVHLFTIVQLSCLILLWVIKTSRA-AIVFPMMVLALVFIRKLLDFFFTKRELSWLDDLMPESKKKRLEDAEKEEEQSILAEEEGVVQVPLEAH------YKDDPSSVNITDEMSKASFGNTWKTMNSDT 1061          
BLAST of slc4a-1 vs. Ensembl Cavefish
Match: slc4a10a (sodium-driven chloride bicarbonate exchanger-like [Source:NCBI gene;Acc:103033693])

HSP 1 Score: 924.465 bits (2388), Expect = 0.000e+0
Identity = 536/1156 (46.37%), Postives = 737/1156 (63.75%), Query Frame = 2
Query:  125 DEPILDRGFQFTHYHPS--EDEIEDHRSQRALYIGVHMPPDXXXXXXXXXXXXXXXXXXXXXDKKDYLTEIAEDDTEKATDPSQHVMFLLG-EDEDEE--THNLFCEMDELRLDDEGEPEWKETARWIKFEEDVEEGGERWSKPHVASLSLYSLFEVRNCITSAVNMFNVEANNFETIIEIILNKIVSEKKISPDQREKVKEMLQRKHVHLHERRHKSNAKGSQLPLIRSLADIGKKYSS-KEVDK-VQLQRRNSDYPTKFTRFDANXXXXXXXXXXXXXYVDKNRIDVDQCGSDNLASQKFDLHFFKKIPLGAETSNIMVGETDFLNQMVVVFIRLKEAVILGELTEVPVPTRFVFVMLGPQGSAVKNHEIGRSMATLMSDDVFHDVAYKARNLDDLLAGIDEFLSNCTVLPPAEWDPSIRIEPPKSGPIA--RKVPSMPNGAQALLTASGDGRXXXXXXXXXXXXXXASVVNKLQPVEEESHADPTLRRTGRLFGGLIEDVKRKAPFYLSDFKDAIHVQCFASFFFLYFACLTPIITFGGLLVQATGGYLGAIESILSGTIVGVVYSLFSGQPLTIMGSTGPVLVFESIVYNICERMRWDYLPFRLWIGVWIAAYLFLMVAFDLSALVRYITRFTEESFAALIALIFMVEAFKKLFLIVDYYPIDTRWNIDMIKNRTCECF----PRNATAMDAFFQKNNKPSNVYMPPMLYPVPLNSSVIDIVNNIDWQNISNYHFTWDYKKYRLICTKWGGIWTGSGCGNY--FIPDVFFFSCLLFIGTFVLSYGLKMMRNAQFFPNWVRSLISDFAVMIAISSMTLLDWSLGFHTPKLNVPAKFEPTLGYKMRGWVIPALGKNPWWTIIIAMGPALLAVILIFMDQQITAVIVNRKENKLKKGSGYHXXXXXXXXXXXXXXXXGIPWFVAATVLSINHVMSLKKESENTAPGERPVFLGCREQRVTGTIIFLVIGLSVFLTPLLKRIPMAVLYGVFLFMGVASLKGVQLMQRISLFFMPAKYQPDYIFLRYVPLRRVHXXXXXXXXXXXXXXXXXXXNVMSICFPIMVLALCFVRKGLEYLFTYNELKWLDDIMPNHKKPPQDDNENDIEKCGSTELIKMTETNLEFNSSTNKVIRSNDSGINISEEMGKTA---IWKQLS 3538
            +E +LDRG   +  + +  ++E+E HR+   LYIGVH+P   + + + +R R H    + +  ++D  TE   +       PSQ V FLLG EDEDEE   H LF E+DE+ L +  + EWKETARW+KFEEDVE+GGERWSKP+VA+LSL+SLFE+R+CI + + M ++ AN+ E I +++L++  +   +  + R+K++  L ++H H ++++       +++P++RS ADIGKK S    +DK  Q+    S  P   +R D +               + + +D            K DLHF KKIP GAE SNI+VGE +FL + VV F+RL  AV+L  L EVP+ TRF+F++LGP G   + HEIGRS+AT+M+D+VFHDVAYKA++  DL+AGIDEFL   TVLPP EWDP+IRIEPPK+ P    RK+P +PNG   L                                E   H  P L+RTG+ FGG   D+KRKAP YLSD+ DAI +QC ASF FLY AC++P+ITFGGLL +AT G + AIES+   ++ G+ YSLF+GQPLTI+GSTGPVLVFE I++  C+     YL  R+ IG+W A +  L+VA D S+LV YITRFTEE+FA+LI +IF+ EA +KL  + ++YP +   +++ +   +C C     P NAT    ++Q+ N  ++                      +DW  +       D K     C  + G + GS CG++  +IPDV F+S +LF  T  +S  LK  + +++FP  VR +ISDFAV I I +M  +D++LG  +PKL VP +F+PT     RGW+I  LG NPWWT II   PALL  ILIFMDQQITAVI+NRKE+KLKKG GYHLDL VV +++ V S++G+PWFVAATVLSI+HV SLK ESE +APGE+P FLG REQR TG +IFL++G SVF+T +LK IPM VLYGVFL+MG +SL+G+Q   R+ LF MPAK+QPD+I+LR+VPLR+VHLFTI+Q+  L +LW+IKT    +I FP+MVLAL F+RK L++ FT  EL WLDD+MP  KK   +D + +  +    E   + +  LE +       + + S +NIS+EM KT+   +WK L+
Sbjct:   29 EEAVLDRGGTRSMLNTNFEKEELEGHRT---LYIGVHVP---LGRRSHRRHRHHGHRHRKRSRERDSGTEDGRESPSFMDTPSQRVQFLLGMEDEDEEHIPHALFTELDEICLREGEDAEWKETARWLKFEEDVEDGGERWSKPYVATLSLHSLFELRSCILNGIVMLDMRANSLEEIADMVLDQQETSIALGEEVRKKIRNALLKQHHHQNQKK-----LANRIPIVRSFADIGKKQSEPHSMDKNGQMVSPQSQPPCTESRSDGSR--------------ENSAVDF----------SKIDLHFMKKIPPGAEASNILVGELEFLEKPVVAFVRLSPAVLLNGLAEVPITTRFLFILLGPMGKGPQYHEIGRSIATIMTDEVFHDVAYKAKDRSDLVAGIDEFLDQVTVLPPGEWDPTIRIEPPKNVPSQEKRKIPPLPNGVTDLGEEG----------------------------EHGGHGGPELQRTGKFFGGFFMDIKRKAPHYLSDYTDAISLQCLASFLFLYCACMSPVITFGGLLGEATEGRISAIESLFGASMTGIAYSLFAGQPLTILGSTGPVLVFEKILFKFCKEYGLSYLSLRVCIGLWTAFFCLLLVATDASSLVCYITRFTEEAFASLICIIFIYEALEKLVHLGEHYPFNMHGDLNKLTQYSCVCTEPKDPSNATL--RYWQEKNITTS---------------------EVDWLGL-------DVKG----CMMYRGEFQGSACGHHGPYIPDVLFWSVILFFATVAMSSFLKEFKTSRYFPTKVRQIISDFAVFITIVTMVGIDFALGVPSPKLQVPNEFKPT--RDDRGWIISPLGPNPWWTTIITSIPALLCTILIFMDQQITAVIINRKEHKLKKGCGYHLDLFVVGVMLGVCSVMGLPWFVAATVLSISHVNSLKLESECSAPGEQPKFLGIREQRFTGLMIFLLMGCSVFMTSVLKFIPMPVLYGVFLYMGASSLRGIQFFDRLKLFGMPAKHQPDFIYLRHVPLRKVHLFTIVQLSCLAMLWIIKTSRA-AIVFPMMVLALVFIRKLLDFFFTKRELSWLDDLMPESKKKKLEDAQQEENQSVMVEDEGIVQVPLEGH------YKDDPSSVNISDEMTKTSFGNVWKSLN 1078          
BLAST of slc4a-1 vs. Ensembl Sea Lamprey
Match: slc4a7 (solute carrier family 4 member 7 [Source:ZFIN;Acc:ZDB-GENE-140106-104])

HSP 1 Score: 794.267 bits (2050), Expect = 0.000e+0
Identity = 431/887 (48.59%), Postives = 576/887 (64.94%), Query Frame = 2
Query:  950 DKNRIDVDQCG-SDNLASQKFDLHFFKKIPLGAETSNIMVGETDFLNQMVVVFIRLKEAVILGELTEVPVPTRFVFVMLGPQGSAVKNHEIGRSMATLMSDDVFHDVAYKARNLDDLLAGIDEFLSNCTVLPPAEWDPSIRIEPPKSGPIA--RKVPSMPNGAQALLTASGDGRXXXXXXXXXXXXXXASVVNKLQPVEEESHADPTLRRTGRLFGGLIEDVKRKAPFYLSDFKDAIHVQCFASFFFLYFACLTPIITFGGLLVQATGGYLGAIESILSGTIVGVVYSLFSGQPLTIMGSTGPVLVFESIVYNICERMRWDYLPFRLWIGVWIAAYLFLMVAFDLSALVRYITRFTEESFAALIALIFMVEAFKKLFLIVDYYPIDTRWNIDMIKNRTCECF----PRNATAMDAFFQKNNKPSNVYMPPMLYPVPLNSSVIDIVNNIDWQNISNYHFTWDYKKYRLICTKWGGIWTGSGCGNY--FIPDVFFFSCLLFIGTFVLSYGLKMMRNAQFFPNWVRSLISDFAVMIAISSMTLLDWSLGFHTPKLNVPAKFEPTLGYKMRGWVIPALGKNPWWTIIIAMGPALLAVILIFMDQQITAVIVNRKENKLKKGSGYHXXXXXXXXXXXXXXXXGIPWFVAATVLSINHVMSLKKESENTAPGERPVFLGCREQRVTGTIIFLVIGLSVFLTPLLKRIPMAVLYGVFLFMGVASLKGVQLMQRISLFFMPAKYQPDYIFLRYVPLRRVHXXXXXXXXXXXXXXXXXXXNVMSICFPIMVLALCFVRKGLEYLFTYNELKWLDDIMPNHKKPP-------QDDNEN-----DIEKCGSTELIKMTETNLEFNSSTNKVIRSNDSGINISEEMGKTAIWKQLSGGT 3547
            D +++   + G S  +   K DL+F +KIP GAE SN++VGE DFL + V+ F+RL  AV+L  L EVP+PTRF+F++LGP G A + HEIGRS+ATLMSD++F DVAYKA++  DLL+GIDEFL   TVLPP EWDPSIRIEPPK+ P    RK+PS+ NGA                               L+P  E   A P L+RTGR+FGGL+ D+KRK PFY SD++D++++QC ASF FLY AC++P+ITFGGLL +AT G + AIES+   ++ G+ YSLF+GQPLTI+GSTGPVLVFE I+Y  C+     YL  R  IG+W A    L+VA D S+LV YITRFTEE+FA+LI +IF+ EA +KL  + + Y ++   + +++   +C C     P N T +DA+   N                         ++I W N++              C +  G + G+ CG++  +IPDV F+S +LF  TF LS  LK  +  ++FP  VRS +SDFAV + I SM ++D+ LG  +PKL VP++F+PT     RGW++  +G NPWWTI+ A  PALL  IL+FMDQQITAVI+NRKE+KLKKG GYHLDLL VAI++ V SI+G+PWFVAATVLSI+HV SLK ESE +APGE+P FLG REQRVTG +IF+++G SVF+T +LK IPM VLYGVFL+MG +SLKG+Q   RI LF MPAK+QPD+I+LR+VPLR+VH          ++L  +   +  +I FP+MVLAL F+RK L++ FT  EL WLDD+MP  +K         Q+D+E      ++ + G+ ++       L+      K    + S INISEEM KTA+WK L+G T
Sbjct:  300 DGDKVCEGRAGESSTVDFSKVDLNFLRKIPQGAEASNVLVGEVDFLERPVIAFVRLSPAVLLSGLAEVPIPTRFLFILLGPSGKATQYHEIGRSIATLMSDEIFSDVAYKAKDRKDLLSGIDEFLDQVTVLPPGEWDPSIRIEPPKNVPSQEKRKLPSLVNGAS----------------------------QALEPEHESHGAGPELQRTGRIFGGLVRDIKRKIPFYWSDYRDSLNLQCIASFLFLYCACMSPVITFGGLLGEATEGRISAIESLFGASMTGIAYSLFAGQPLTILGSTGPVLVFEKILYKFCKDYNLSYLSLRACIGLWTAFLCLLLVATDASSLVCYITRFTEEAFASLICIIFIYEALEKLVHLGETYEVNMHADPELLTQYSCVCVEPSVPSNET-LDAWSNMNRS----------------------ADSIPWGNLTVSK-----------CLELHGQFVGTACGHHGPYIPDVLFWSIILFFATFFLSGFLKQFKTMRYFPTKVRSTVSDFAVFLTILSMVVIDYFLGIPSPKLQVPSEFKPT--RDDRGWIVDPIGPNPWWTILAAAIPALLCTILVFMDQQITAVIINRKEHKLKKGCGYHLDLLWVAIMLAVCSIMGLPWFVAATVLSISHVNSLKVESECSAPGEQPKFLGIREQRVTGLMIFVLMGCSVFMTGVLKFIPMPVLYGVFLYMGASSLKGIQFFDRIKLFVMPAKHQPDFIYLRHVPLRKVH-LFTAVQFTCLVLLWVIKASPAAIVFPMMVLALVFIRKLLDFCFTKRELSWLDDLMPESRKKKLEDALREQEDSEETQRILEVAEVGTVQVPLEGGNVLKIPVKGIKFSHHDPSIINISEEMSKTAVWKTLAGNT 1121          

HSP 2 Score: 163.31 bits (412), Expect = 7.246e-41
Identity = 78/158 (49.37%), Postives = 116/158 (73.42%), Query Frame = 2
Query:  362 PSQHVMFLLG-EDEDEE--THNLFCEMDELRLDDEGEPEWKETARWIKFEEDVEEGGERWSKPHVASLSLYSLFEVRNCITSAVNMFNVEANNFETIIEIILNKIVSEKKISPDQREKVKEMLQRKHVHLHERRHKSNAKGSQLPLIRSLADIGKKYS 826
            PSQ V F+LG ED+DEE  +H+LF EMDEL + D  E EW+ETARW+KFEEDVE+GGERWSKP+VA+LSL+SLFE+R+CI +   M +++A   E I +++L+  ++  ++    R++V++ L ++H H  E++        ++P++RSLAD+GKKYS
Sbjct:    3 PSQRVQFILGVEDDDEEHVSHDLFTEMDELCMRDGEECEWRETARWLKFEEDVEDGGERWSKPYVATLSLHSLFELRSCIMNGTVMLDMKATTLEEIADLVLDSQIASGQLDVAVRDRVRQALLKRHHHQSEKK-----LSHRIPIVRSLADMGKKYS 155          
BLAST of slc4a-1 vs. Ensembl Sea Lamprey
Match: slc4a7 (solute carrier family 4 member 7 [Source:ZFIN;Acc:ZDB-GENE-140106-104])

HSP 1 Score: 555.444 bits (1430), Expect = 1.159e-179
Identity = 289/604 (47.85%), Postives = 389/604 (64.40%), Query Frame = 2
Query:  989 NLASQKFDLHFFKKIPLGAETSNIMVGETDFLNQMVVVFIRLKEAVILGELTEVPVPTRFVFVMLGPQGSAVKNHEIGRSMATLMSDDVFHDVAYKARNLDDLLAGIDEFLSNCTVLPPAEWDPSIRIEPPKSGPIA--RKVPSMPNGAQALLTASGDGRXXXXXXXXXXXXXXASVVNKLQPVEEESHADPTLRRTGRLFGGLIEDVKRKAPFYLSDFKDAIHVQCFASFFFLYFACLTPIITFGGLLVQATGGYLGAIESILSGTIVGVVYSLFSGQPLTIMGSTGPVLVFESIVYNICERMRWDYLPFRLWIGVWIAAYLFLMVAFDLSALVRYITRFTEESFAALIALIFMVEAFKKLFLIVDYYPIDTRWNIDMIKNRTCECF-PRNATAMDAFFQKNNKPSNVYMPPMLYPVPLNSSVIDIVNNIDWQNISNYHFTWDYKKYRLICTKWGGIWTGSGCGNY--FIPDVFFFSCLLFIGTFVLSYGLKMMRNAQFFPNWVRSLISDFAVMIAISSMTLLDWSLGFHTPKLNVPAKFEPTLGYKMRGWVIPALGKNPWWTIIIAMGPALLAVILIFMDQQITAVIVNRKENKLKKGSGYH 2785
            N+   K DL+F +KIP GAE SN++VGE DFL + ++ F+RL  AV+L  +TEVP+PTRF+F +LGP G A + HEIGRS+ATLM+D++FHDVAYKA++ +DLLAGIDEFL   TVLPP EWDPSIRIEPPKS P    RK+P++PNG      A G                        +P  E     P L+RTGRLFGGL+ D+KRK P+Y SD++DA+ +QC ASF FLY AC++P+ITFGGLL +AT   + AIES+   ++ G+ +SLF+GQPLTI+GSTGPVLVFE I+Y  C+     YL  R  IG+W A    L+VA D S+LV YITRFTEE+FA+LI +IF+ EA +KL  + + Y +++  +++ + + +C C  P++ +       +N                LN +     ++I W N++              C +  G + GS CG++  F+PDV F+S +LF  T  LS   K  +  ++FP  VRS +SDFAV + I SM L+D++LG  +PKL VP++F+PT     RGW +  +G NPWWT   A+ PALL  ILIFMDQQITAVI+NRKE+KLKKG GYH
Sbjct:  403 NMDFSKVDLNFMRKIPPGAEASNVLVGEVDFLERPLIAFVRLSPAVLLTGITEVPIPTRFLFFLLGPPGKAQQYHEIGRSIATLMADEIFHDVAYKAKDRNDLLAGIDEFLDQVTVLPPGEWDPSIRIEPPKSVPSQEKRKMPNVPNGG-----APG-----------------------AEPEHEGHGMGPELQRTGRLFGGLVVDIKRKLPWYWSDYRDALSLQCVASFLFLYCACMSPVITFGGLLGEATENRISAIESLFGASMTGIAFSLFAGQPLTILGSTGPVLVFEKILYKFCKDYGLSYLSLRASIGLWTAFLCLLLVATDASSLVCYITRFTEEAFASLICIIFIYEALEKLVHLGETYEVNSHGDLEQLTHYSCSCVEPQDPSNKTLLLWQN----------------LNVT----PDSIPWANLTVS-----------TCQQLHGDFVGSACGHHGPFVPDVLFWSVILFFCTVFLSAFFKQFKTMRYFPTKVRSTVSDFAVFLTILSMVLVDYALGIPSPKLKVPSEFKPT--RDDRGWFVNPIGTNPWWTFPAALVPALLCTILIFMDQQITAVIINRKEHKLKKGCGYH 945          

HSP 2 Score: 179.874 bits (455), Expect = 3.139e-46
Identity = 107/255 (41.96%), Postives = 164/255 (64.31%), Query Frame = 2
Query:  125 DEPILDRGFQFTHYHPSEDEIEDHRSQRALYIGVHMPPDXXXXXXXXXXXXXXXXXXXXXDKKDYLTEIAEDDTEKAT--DPSQHVMFLLG-EDEDEE--THNLFCEMDELRLDDEGEPEWKETARWIKFEEDVEEGGERWSKPHVASLSLYSLFEVRNCITSAVNMFNVEANNFETIIEIILNKIVSEKKISPDQREKVKEMLQRKHVHLHERRHKSNAK-GSQLPLIRSLADIGKKYSSKEVDKVQLQRRNSD 871
            +E ++DRG   T  H +  E ED  + R +YIG+H+P        R  RR   +  +  H +++   E ++DD E +    PSQ V F+LG ED+DEE   H+LF EMDE+ + D  E EW+ETARW+KFEEDVE+GGERWSKP+VA+LSL+SLFE+R+CI S   M +++A+  + I +++L+  VS   +    R+++++ L RKH      RH++++K  +++P++RSLAD+GKKYS      V +Q +N +
Sbjct:   15 EEAVVDRGKTST-IHTTNFEKEDLDAHRTVYIGLHVP-----SGRRSHRRHRHRGHRHHHRRREREREASQDDAESSAYDTPSQRVQFILGTEDDDEEHIPHDLFTEMDEICMRDGDESEWRETARWLKFEEDVEDGGERWSKPYVATLSLHSLFELRSCIMSGTVMLDMKASTLDEIADMVLDNQVSSGLLDESVRDRMRDALLRKH------RHQNDSKLSNKIPIVRSLADMGKKYSD-----VHVQDKNDE 252          
BLAST of slc4a-1 vs. Ensembl Sea Lamprey
Match: SLC4A2 (solute carrier family 4 member 2 [Source:HGNC Symbol;Acc:HGNC:11028])

HSP 1 Score: 525.398 bits (1352), Expect = 1.930e-167
Identity = 350/999 (35.04%), Postives = 510/999 (51.05%), Query Frame = 2
Query:  398 EDEETHNLFCEMDELRLD-DEGEPEWKETARWIKFEEDVEEGGERWSKPHVASLSLYSLFEVRNCITSAVNMFNVEANNFETIIEIILNKIVSEKKISPDQREKVKEMLQRKHVHLHERRHKSNAKGSQLPLIRSLADIGKKYSSKEVDKVQLQRRNSDYPTKFTRFDANXXXXXXXXXXXXXYVDKNRIDVDQ--CGSDNLASQKFDLHFFKKIPLGAETSNIMVGETDFLNQMVVVFIRLKEAVILGELTEVPVPTRFVFVMLGPQGSAVKNHEIGRSMATLMSDDVFHDVAYKARNLDDLLAGIDEFLSNCTVLPPAEW--DPSIR---------IEPPKSGPIARKVPSMPNGAQALLTASGDGRXXXXXXXXXXXXXXASVVNKLQPVEEESHADPTLRRTGRLFGGLIEDVKRKAPFYLSDFKDAIHVQCFASFFFLYFACLTPIITFGGLLVQATGGYLGAIESILSGTIVGVVYSLFSGQPLTIMGSTGPVLVFESIVYNICERMRWDYLPFRLWIGVWIAAYLFLMVAFDLSALVRYITRFTEESFAALIALIFMVEAFKKLFLIVDYYPIDTRWNIDMIKNRTCECFPRNATAMDAFFQKNNKPSNVYMPPMLYPVPLNSSVIDIVNNIDWQNISNYHFTWDYKKYRLICTKWGGIWTGSGCGNYFIPDVFFFSCLLFIGTFVLSYGLKMMRNAQFFPNWVRSLISDFAVMIAISSMTLLDWSL-GFHTPKLNVPAKFEPTLGYKMRGWVIPALGKN---PWWTIIIAMGPALLAVILIFMDQQITAVIVNRKENKLKKGSGYHXXXXXXXXXXXXXXXXGIPWFVAATVLSINHVMSLKKESENTAPGERPVFLGCREQRVTGTIIFLVIGLSVFLTPLLKRIPMAVLYGVFLFMGVASLKGVQLMQRISLFFMPAKYQPDYIFLRYVPLRRVHXXXXXXXXXXXXXXXXXXXNVMSICFP-IMVLALCFVRKGLEYLFTYNELKWLD 3337
             D   H +F E++EL +D    E +WKETARWIKFEEDVE   +RW KPHVASL+  SL E+R  I+    + ++E     TI   ++ +++   +I  + R  V   L  +H H ++   K    GS LP   S   +G   +    +        S  P        N                 + +  D    G  +    K +     KIP GAE + ++VG  DFL Q  + F+RL E V+L  + EVPVP RF+FV+LGP  + +  HEIGRS++TLMSD  FH+ AY A    DLL  + EFL    VLPP+E   D  +R         ++  +    ++K+  +P  A+   TA    R                        +E+   D  LRR+GRLFGGL+ D +R+ P YLSD +DA++ QC A+  F+YFA L+P ITFGGLL + T G +G  E I+S  + G++++L   QPL I+G +GP+LVFE   ++ C     +YL  R+WIG W+   + L+VAF+ S +VR+I+RFT+             E F  L  ++  Y                E F +    +   FQ +         P+L   P+ S   ++  N D  N S  + T                 T +       P+    S LL  GTF +++ L+  +N++F    VR +I DF V IAI  M L+D+ +   +T KLNVP  F  T   K RGWVI  LG     P W +   + P LL  ILIFM+ QIT +IV++KE  L KGSG+HLDLL++ ++  + +I G+PW  AATV S+ HV +L   S+ TAPG++P     +EQR+TG ++ +++GLS+ L  +L++IP+AVL+G+FL+MGV SL G+Q   R+ L FMPAKY PD  +   V   R++        + +           S+ FP +++L +   R  L  +FT  ELK LD
Sbjct:   88 HDRRPHEVFVELNELVMDPARQERQWKETARWIKFEEDVEAETDRWGKPHVASLTFRSLLELRKAISHGTVLLDLEQKTLPTIAHQVVEQLIISDQIREEDRANVLRALLLRHRHPND--MKEVPVGSFLPRNISATSLGSLLAGSGGNGGAAGDPVSSQP-----LVGNVLIEMGEAGDHETSEHAHSLTRDNSLTGDSHRIKPKKEGKLLGKIPQGAEATVVLVGCVDFLEQPAMAFVRLSEGVLLESVLEVPVPVRFLFVLLGPSEAHMDYHEIGRSISTLMSDKDFHEAAYVADERQDLLNAMTEFLDVSIVLPPSELTDDGLLRSVAAFQRDMLQKRRQEDESKKLNIVPTSAELKQTAVPSQR------------------------KEDDDPDDPLRRSGRLFGGLVRDARRRYPHYLSDLRDALNPQCLAAVIFIYFAALSPAITFGGLLSEKTQGLMGVSELIISTCLQGILFALLGAQPLLIIGFSGPLLVFEEAFFSFCSSQGVEYLTGRVWIGFWMVLIVLLLVAFEGSFMVRFISRFTQ-------------EIFSILISLIFIY----------------ETFSK----LYKVFQDH---------PLLSTYPVIS---NMTTNSDTSNSSIVNGT-----------------TAATPKVLNQPNTALLSLLLMSGTFFIAFFLRKFKNSRFLAGKVRRVIGDFGVPIAILVMVLVDFGVPNTYTQKLNVPDGFSVTSPSK-RGWVINPLGAEGTFPVWLMFACVIPGLLVFILIFMESQITTLIVSKKERMLLKGSGFHLDLLLIVVMGAICTIFGLPWLTAATVRSVTHVNALTVMSKATAPGDKPRIECVKEQRITGLLVAIIVGLSMVLGQVLRQIPLAVLFGIFLYMGVTSLNGIQFYDRLMLVFMPAKYHPDTAYATKVRTLRMN-LYTGIQFVCLGGLWAVMSTAASLAFPFVLILTVPLRRFLLSRIFTDRELKCLD 991          
BLAST of slc4a-1 vs. Ensembl Sea Lamprey
Match: SLC4A4 (solute carrier family 4 member 4 [Source:HGNC Symbol;Acc:HGNC:11030])

HSP 1 Score: 431.409 bits (1108), Expect = 1.323e-138
Identity = 232/494 (46.96%), Postives = 316/494 (63.97%), Query Frame = 2
Query: 1562 LRRTGRLFGGLIEDVKRKAPFYLSDFKDAIHVQCFASFFFLYFACLTPIITFGGLLVQATGGYLGAIESILSGTIVGVVYSLFSGQPLTIMGSTGPVLVFESIVYNICERMRWDYLPFRLWIGVWIAAYLFLMVAFDLSALVRYITRFTEESFAALIALIFMVEAFKKLFLIVDYYPIDTRWNIDMIKNRTCECFPRNATAMDAFFQKNNKPSNVYMPPMLYPVPLNSSVIDIVNNI-----DWQNISNYHFTWDYKKYRLICTKWGGIWTGSGCGNYFIPDVFFFSCLLFIGTFVLSYGLKMMRNAQFFPNWVRSLISDFAVMIAISSMTLLDWSLGFHTPKLNVPAKFEPTLGYKMRGWVIPALGKNPWWTIIIAMGPALLAVILIFMDQQITAVIVNRKENKLKKGSGYHXXXXXXXXXXXXXXXXGIPWFVAATVLSINHVMSLKKESENTAPGERPVFLGCREQRVTGTIIFLVIGLSVFLTPLLKRIP 3028
            L+RTGRLFGGL +D+KRK PF+ SD  DA+ +Q  ++  F+Y A +T  ITFGGLL  AT    G +ES L   + G V+ LF+GQPL I+ STGPVLVFE +++N  +   +DYL FRLWIG+W A    ++VA D S LV+Y TRFTEE F+ALI+ IF+ +A KK+  + +YYPI+  +  D I   +C C  +    ++ F       +    P        N ++  + +       DW  +S              C+K+GG  +G  C   F+PDV   S LLF+GT+  +  LK  +  ++FP  VR LISDF+++ +I     LD  +G  TPKL VP++F+PT     RGW +P  G NPWW  +++  PA+L  IL+FMDQQITA+IVNRKENKLKKGSGYHLDL  VA+L+   S LG+PW+VAATVLSI H+ SLK E+E +APGE+P FLG REQR+TG ++F++ G+SVFL P+LK+IP
Sbjct:   27 LQRTGRLFGGLFKDIKRKLPFFCSDIYDALSIQSLSATLFIYLATITNAITFGGLLGDATDNMQGVLESFLGTALSGAVFCLFAGQPLIILSSTGPVLVFERLLFNFSKENDFDYLEFRLWIGLWSAFMSLILVATDASYLVQYFTRFTEEGFSALISFIFIYDAIKKMLGLFNYYPINLDYKPDYITLYSCTC--QAPDPVNYFVNGTLTVATTLGP--------NDTIFSLSDQYFSVRPDWSALSKKE-----------CSKYGGSLSGKACK--FVPDVALVSLLLFMGTYYTTMALKRFKTGRYFPTTVRKLISDFSIIFSILLFCGLDALVGLETPKLLVPSEFKPTSA--KRGWFVPPFGGNPWWVYLVSAVPAILITILVFMDQQITAIIVNRKENKLKKGSGYHLDLFWVAVLMATCSFLGLPWYVAATVLSIAHIDSLKMETETSAPGEQPKFLGVREQRITGVLVFVLTGVSVFLAPILKKIP 495          
BLAST of slc4a-1 vs. Ensembl Sea Lamprey
Match: SLC4A4 (solute carrier family 4 member 4 [Source:HGNC Symbol;Acc:HGNC:11030])

HSP 1 Score: 422.165 bits (1084), Expect = 6.783e-136
Identity = 228/484 (47.11%), Postives = 305/484 (63.02%), Query Frame = 2
Query: 1577 RLFGGLIEDVKRKAPFYLSDFKDAIHVQCFASFFFLYFACLTPIITFGGLLVQATGGYLGAIESILSGTIVGVVYSLFSGQPLTIMGSTGPVLVFESIVYNICERMRWDYLPFRLWIGVWIAAYLFLMVAFDLSALVRYITRFTEESFAALIALIFMVEAFKKLFLIVDYYPIDTRWNIDMIKNRTCECFPRNATAMDAFFQKNNKPSNVYMPPMLYPVPLNSSVIDIVNNIDWQNISNYHFTWDYKKYRLICTKWGGIWTGSGCGNYFIPDVFFFSCLLFIGTFVLSYGLKMMRNAQFFPNWVRSLISDFAVMIAISSMTLLDWSLGFHTPKLNVPAKFEPTLGYKMRGWVIPALGKNPWWTIIIAMGPALLAVILIFMDQQITAVIVNRKENKLKKGSGYHXXXXXXXXXXXXXXXXGIPWFVAATVLSINHVMSLKKESENTAPGERPVFLGCREQRVTGTIIFLVIGLSVFLTPLLKRIP 3028
            RLFGGL +D+KRK PF+ SD  DA+ +Q  ++  F+Y A +T  ITFGGLL  AT    G +ES L   + G V+ LF+GQPL I+ STGPVLVFE +++N  +   +DYL FRLWIG+W A    ++VA D S LV+Y TRFTEE F+ALI+ IF+ +A KK+  + +YYPI+  +  D I   +C C      A D          N   P                   DW  +S              C+K+GG  +G  C   F+PDV   S LLF+GT+  +  LK  +  ++FP  +R LISDF+++++I +   LD  +G  TPKL VP +F+PT     RGW +P  G NPWW  +++  PA+L  IL+FMDQQITA+IVNRKENKLKKGSGYHLDL  VA+L+   S LG+PW+VAATVLSI H+ SLK E+E +APGE+P FLG REQR+TG ++F++ G+SVFL P+LK+IP
Sbjct:    1 RLFGGLFKDIKRKLPFFCSDIYDALSIQSLSATLFIYLATITNAITFGGLLGDATDNMQGVLESFLGTALSGAVFCLFAGQPLIILSSTGPVLVFERLLFNFSKENDFDYLEFRLWIGLWSAFMSLILVATDASYLVQYFTRFTEEGFSALISFIFIYDAIKKMLGLFNYYPINLDYKPDYITLYSCTC-----QAPDPVLMIKPDLGNATGP-------------------DWSALSKKE-----------CSKYGGSLSGKACK--FVPDVALVSLLLFMGTYYTTMALKRFKTGRYFPTTIRKLISDFSIILSIFTFVGLDILIGLETPKLVVPTEFKPT--SAKRGWFVPPFGGNPWWVYLVSAVPAILITILVFMDQQITAIIVNRKENKLKKGSGYHLDLFWVAVLMATCSFLGLPWYVAATVLSIAHIDSLKMETETSAPGEQPKFLGVREQRITGVLVFVLTGVSVFLAPILKKIP 445          
BLAST of slc4a-1 vs. Ensembl Yeast
Match: BOR1 (Boron efflux transporter of the plasma membrane; binds HCO3-, I-, Br-, NO3- and Cl-; has similarity to the characterized boron efflux transporter A. thaliana BOR1 [Source:SGD;Acc:S000005219])

HSP 1 Score: 90.1225 bits (222), Expect = 6.754e-19
Identity = 51/168 (30.36%), Postives = 84/168 (50.00%), Query Frame = 2
Query: 1565 RRTGRLFGGLIEDVKRKAPFYLSDFKDAIHVQCFASFFFLYFACLTPIITFGGLLVQATGGYLGAIESILSGTIVGVVYSLFSGQPLTIMGSTGPVLVFESIVYNICERMRWDYLPFRLWIGVWIAAYLFLMVAFDLSALVRYITRFTEESFAALIALIFMVEAFKKL 2068
            RR   L  G+  D+K + P+Y SD+ DA + +   S    YF  L P I F   +   T    G  E +LS  + G+V+ +  GQPL I+G TGP+ +F   VY I + +   Y  F  WI +W   +  ++   +   L++Y+T F  + F   I ++++ +  + L
Sbjct:   53 RRFPTLGIGIWLDLKDRIPYYKSDWVDAFNYRVIPSIVDTYFNNLLPAIAFAQDMFDRTDNSYGVNEVLLSSAMAGIVFGVLGGQPLCIVGVTGPISIFNYTVYEIIKPLNTSYFGFMFWICMWSMIFHLVLAFTNAVCLLQYVTTFPCDIFGLFINVVYIQKGIQIL 220          

HSP 2 Score: 61.2326 bits (147), Expect = 6.403e-10
Identity = 65/242 (26.86%), Postives = 107/242 (44.21%), Query Frame = 2
Query: 2438 SYGL--KMMRNAQFFPNWVRSLISDFAVMIAISSMTLLDWSLGFHT---------PKLNVPAKFEPT--LGYKMRGWVIPALGKNPWWTIIIAMGPALLAVILIFMDQQITAVIVNRKENKLKKGSGYHXXXXXXXXXXXXXXXXGIPWFVAATVLSINHVMSLKKESENTAPGERPVFLGCREQRVTGTIIFLVIGLSVFLTPLL---KRIPMAVLYGVFLFMGVASLKGVQLMQRISLFF 3115
            ++GL  K+      F + +R+ ISD++     +++++L WS   H           KL +   F PT  +      W+  A    P   + IA+   +   IL + D  +++++  R + KLKK S +H D  ++ +   ++ +LGIP        +  H  +L     N         + C EQR T T   L+I L     PLL     IP AVL G+F  MG+  L    ++QR+   F
Sbjct:  248 AFGLFFKLFHYYPLFSHRIRTFISDYS-----TALSVLFWSSFTHFGGYLHDVKFKKLPITKAFFPTSKVNRPQNTWL--AYEPIPVKDVFIALPFGIFLTILFYFDHNVSSLMAQRHQYKLKKPSSFHYDFALLGLTTCISGVLGIPAPNGLIPQAPLHTETLLVRDSNQK------VISCVEQRFTNTFQGLMI-LGTMTRPLLVCLGEIPQAVLSGLFFIMGINGLMTNSIIQRLVFLF 475          
BLAST of slc4a-1 vs. Ensembl Nematostella
Match: EDO45844 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RRK7])

HSP 1 Score: 500.36 bits (1287), Expect = 8.903e-159
Identity = 336/985 (34.11%), Postives = 522/985 (52.99%), Query Frame = 2
Query:  401 DEETHNLFCEMDELRLDDEGEPEWKETARWIKFEEDVEEGGERWSKPHVASLSLYSLFEVRNCITSAVNMFNVEANNFETIIEIILNKIVSEKKISPDQREKVKEMLQRKHVHLHERRHKSNAKGSQLPLIRSLADIGKKYSSKEVDKVQL---QRRNSDYPTKFTRFDANXXXXXXXXXXXXXYVDKNRIDVDQCGSDNLASQKFDLHFFKKIPLGAETSNIMVGETDFLNQMVVVFIRLKEAVILGELTEVPVPTRFVFVMLGPQGSAVKNHEIGRSMATLMSDDVFHDVAYKARNLDDLLAGIDEFLSNCTVLPPAEWDPSIRIEPPKSGPIARKVPSMPNGAQALLTASGDGRXXXXXXXXXXXXXXASVVNKLQPVEEESHADPTLRRTGRLFGGLIEDVKRKAPFYLSDFKDAIHVQCFASFFFLYFACLTPIITFGGLLVQATGGYLGAIESILSGTIVGVVYSLFSGQPLTIMGSTGPVLVFESIVYNICERMRWDYLPFRLWIGVWIAAYLFLMVAFDLSALVRYITRFTEESFAALIALIFMVEAFKKLFLIVDYYPIDTRWNIDMIKNRTCECFPRNATAMDAFFQKNNKPSNVYMPPMLYPVPLNSSVIDIVNNIDWQNISNYHFTWDYKKYRLICTKWGGIWTGSGCGNYFIPDVFFFSCLLFIGTFVLSYGLKMMRNAQFFPNWVRSLISDFAVMIAISSMTLLDWSL--GFHTPKLNV----PAKFEPTLGYKMRGWVIPALG-----KNPWWTIIIAMGPALLAVILIFMDQQITAVIVNRKENKLKKGSGYHXXXXXXXXXXXXXXXXGIPWFVAATVLSINHVMSLKKESENTAPGERPVFLGCREQRVTGTIIFLVIGLSVFLTPLLKRIPMAVLYGVFLFMGVASLKGVQLMQRISLFFMPAKYQPDYIFLRYVPLRRVHXXXXXXXXXXXXXXXXXXXNVMSICFPIMVLALCFVRKGLEYLFT 3313
            D   H  F E+ EL   D+ +  WKETARWIKFEEDVE+   RWSKPHVASLS +SL E+R  +     + ++E  + ++I E I++ +V   ++  +  ++V   L  KH H ++       + S   L     ++ ++ + ++ + V++   Q+   D  T   R                  +D N IDV   GS    +Q+ D+    ++P  AE +N++VG  D L   V  F+RL +   LG +TEV +P RF+FVMLGP+  +   HEIGRS+ATLMSD VFHD+AY + + +D+L  I+EFL +  VLPP EWD  + I            P + + ++ +       +  N   T              Q  EEE   D  L+RTGR  GGLI+D+K ++  Y+SDFKD  + QC     FLYFA   P + FGGLL + T  +LG  E I +    G++++LFSGQPL I+G+TGPV+VFE  ++  CE+   ++LP+R WIG W+   LFL+VAF+   LVRY TRFTEE FA LI+            LI  Y  I+  + +                     F+KN               PL+   +  + NID            Y K  ++        TG        P+      +L  GT+ +++ ++  RN+ FF    R L+SDF + IA+ +M ++D ++     TPK+++       F PTL  K RGW I  +G     K  W  +  A+ PAL   IL+FM+ ++T V++N+KEN L+K  GY++DLL++ ++ L+ S+ G+PW   ATV S++H  +L   S + APGE+P  +  REQR+T  +I ++ G+S+ L P+L  +P+ VL+GV L++G++SL  +QL+ R+ +  MP K+ PD  ++R VP  ++H    +  +  +L+ +   + +++  FP  ++ L  VR+ L  +F+
Sbjct:   49 DHSPHEAFIELQELTGKDQ-DMRWKETARWIKFEEDVEDSN-RWSKPHVASLSFHSLLELRKGLERGTVLLDLEQFDLQSIAEAIVDNMVITDQLCKEDSDRVLSALLVKHKHQYQEAGNLPRRPSFYNLKTFTPNLSRRNNEEDKNSVKMVVTQKVPVDEETDMIRLK----------------IDDN-IDV---GSHT--NQESDVK--ARVPEDAEATNVLVGTLDCLKNPVTAFVRLAKGCYLGNVTEVAIPVRFLFVMLGPETQSDTYHEIGRSIATLMSDQVFHDLAYYSESREDILMAINEFLDDTVVLPPGEWDKQLLI------------PVLLSQSKTMAKRRKQAKEINAIAT--------------QAAEEE---DNPLKRTGRFCGGLIQDIKHRSKTYISDFKDGFNWQCLLVTVFLYFAVFAPNVAFGGLLAEKTDQWLGVSEVIFASCFCGLLFALFSGQPLIIIGATGPVMVFEQTIFKFCEQSNIEFLPWRCWIGFWVLVILFLVVAFEGCFLVRYFTRFTEELFACLIS------------LIFIYEAINFLYKV---------------------FKKN---------------PLSRDPVTNLTNID-----------PYIKENIVPV------TGE-------PNTALLCAILMFGTYFVAFYMRKFRNSHFFGKKARRLVSDFGIAIAMITMVIIDVAIRDTVITPKISIGDVTKVGFHPTLKTK-RGWFINPMGLVDSMKAGW--VFAAIIPALFVGILLFMETELTGVLINKKENCLQKRPGYNMDLLLMGVITLICSLFGLPWMCPATVRSVSHFNALSVWSTSHAPGEKPYLVEVREQRITNILIHVLTGMSILLAPVLHHVPVPVLFGVLLYLGLSSLSNLQLINRLIMMLMPPKHHPDVRYVRKVPTAKIH-GYTLIQLACLLVLMAVKLTILAPSFPFFIICLIPVRRLLGKVFS 902          
BLAST of slc4a-1 vs. Ensembl Nematostella
Match: EDO31793 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SWX4])

HSP 1 Score: 334.724 bits (857), Expect = 3.100e-98
Identity = 200/583 (34.31%), Postives = 312/583 (53.52%), Query Frame = 2
Query:  377 MFLLGEDEDEETHNLFCEMDELRLDDEGEPEWKETARWIKFEEDVEEGGERWSKPHVASLSLYSLFEVRNCITSAVNMFNVEANNFETIIEIILNKIVSEKKISPDQREKVKEMLQRKHVHLHERRHKSNAKGSQLPLIRSLADIGKKYSSKEVDKVQLQRRNSDYPTKFT-RFDANXXXXXXXXXXXXXYVDKNRIDVDQCGSDNLASQKFDLHFFKKIPLGAETSNIMVGETDFLNQMVVVFIRLKEAVILGELTEVPVPTRFVFVMLGPQGSAVKNHEIGRSMATLMSDDVFHDVAYKARNLDDLLAGIDEFLSNCTVLPPAEWDPSIRIEPPKSGPIARKVPSMPNGAQALLTASGDGRXXXXXXXXXXXXXXASVVNKLQPVEEESHADPTLRRTGRLFGGLIEDVKRKAPFYLSDFKDAIHVQCFASFFFLYFACLTPIITFGGLLVQATGGYLGAIESILSGTIVGVVYSLFSGQPLTIMGSTGPVLVFESIVYNICERMRWDYLPFRLWIGVWIAAYLFLMVAFDLSALVRYITRFTEESFAALIALIFMVEAFKKLFLIVDYYPID--TRWNID 2116
            M   GE+E    H  F E++EL   D+ +  WKETARWIKFEEDVE+   RW KPH+  L  +S  EVR    +   + +++ +   +I E + +K++S+ K+S  + +    +L   H H  +++      G  +  + ++  IGK+           Q RN++    F+  F +        K   +    ++ + VD    DN  S         +IP  AE + ++VG    L+     F+RL     L  L EV +P RF+F++LGP   ++  HE+GR +ATLMSD +F D AY A  L DL   +D FLS+  ++PP EWD ++         +A+ +PS+    +        G         S      +V   L     E   DP L+RTG   GGL+ DVKR+ P+Y SD  D+ + +C  +   +Y ACL P I+FGGLL + T G++G  E I+S  + GV+++LF+GQPL I+G+TGP+L+FE+ V+N+ E   ++Y+P+R W+G+W+    + +VA +   L+RY TRFTEE FA +I+LIF+ +  K ++ I   YP+   T  N+D
Sbjct:    1 MAFYGEEEGLSLHEGFVELEELSCSDD-KLIWKETARWIKFEEDVEKNANRWGKPHIPCLGFHSCQEVRTVFQNGCLLLDLDEDQLPSIAEAVASKLISDGKLSEKEHDAFLSILLTPHEHQFQKQRS----GGGIRKLSTIHPIGKE-----------QGRNTNQNDFFSILFSSIPHVEIATKPGGNTSRAQDSLAVDTI--DNKVSS-----IDARIPKDAEATTVLVGGHKHLSAPEGAFVRLARGCRLRNLAEVNIPVRFLFILLGPDDKSIDYHEVGRCVATLMSDRLFLDCAYDAEELQDLYDAMDSFLSDTVIIPPGEWDRNV---------LAQSLPSLAKETKKT-ALRRRGALLRKQRHFSDLETQETVTESL-----ELEDDP-LKRTGLFCGGLLRDVKRRFPYYKSDMTDSFNWRCVMATILVYVACLAPAISFGGLLYKKTKGWMGVAEMIVSTALSGVIFALFAGQPLIIIGATGPLLLFETNVFNLSESFDFEYMPWRAWVGIWVMLICWALVAMEGCFLIRYFTRFTEEIFACMISLIFIYDGIKYIYDIFGLYPLTSGTTENVD 544          

HSP 2 Score: 180.259 bits (456), Expect = 3.276e-46
Identity = 112/314 (35.67%), Postives = 193/314 (61.46%), Query Frame = 2
Query: 2384 IPDVFFFSCLLFIGTFVLSYGLKMMRNAQFFPNWVRSLISDFAVMIAISSMTLLDWSL-GFHTPKLNVPAKFEPTLGYKMRGWVIPALGKNPWW---TIIIAMGPALLAVILIFMDQQITAVIVNRKENKLKKGSGYHXXXXXXXXXXXXXXXXGIPWFVAATVLSINHVMSLKKESENTAPGERPVFLGCREQRVTGTIIFLVIGLSVFLTPLLKRIPMAVLYGVFLFMGVASLKGVQLMQRISLFFMPAKYQPDYIFLRYVPLRRVHXXXXXXXXXXXXXXXXXXXNVMSICFPIMVLALCFVRKGLEYLFT 3313
            + +   F+ +LF GTF +++ ++ +R+++F  + +R +ISDF V+IAI +M L++ S    +  +LNVP  F+ T  + +RGW +  +G         I  A+ PA+L  IL+FM+ +   VI+++K+N+LKKG GY+LDL VV  L+ + S+LG+PW  A  V +++H+ +L   S N APGE P  L  +EQRVT  II ++IGL++ L P+++  P+ VL+GVF+ +G +SL  +Q ++R  L F+   + PD  ++R V   +++    +  ++ +L  V   + V++  FP  V+ L  +R+ LE  +T
Sbjct:  548 VSNTALFTTILFFGTFFVAHIIRDVRHSRFLNHTLRRVISDFGVLIAIVAMILVELSAQSIYVQRLNVPDGFDVTSPH-LRGWYVNPMGTERRLGADAIFGALVPAILVSILVFMEVEFCNVILDKKDNQLKKGPGYNLDLFVVGFLMGMCSVLGLPWMCATPVHTVSHLHALMVHSTNHAPGEHPQLLEVKEQRVTNIIIHVLIGLTMLLAPVIRLTPVVVLFGVFVHLGFSSLSHLQFVERFKLLFVSPNHHPDRRYVRSVSTGKMN-AFTLVQVVCLLFLVAIKVTVVAPFFPFFVICLVPLRRMLERFYT 859          
BLAST of slc4a-1 vs. Ensembl Nematostella
Match: EDO27089 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7TA82])

HSP 1 Score: 139.428 bits (350), Expect = 1.264e-38
Identity = 65/114 (57.02%), Postives = 87/114 (76.32%), Query Frame = 2
Query: 1757 AIESILSGTIVGVVYSLFSGQPLTIMGSTGPVLVFESIVYNICERMRWDYLPFRLWIGVWIAAYLFLMVAFDLSALVRYITRFTEESFAALIALIFMVEAFKKLFLIVDYYPID 2098
            A+E +L G I G++++LFSGQPL I+G+TGP+LVFE IVY  CER+  +YL FRLWIG+W   +  ++V  D SA++ Y TRFTEE+FA LIA+I++ E FKKLF I+D YPI 
Sbjct:    1 AMEQMLGGAIGGILFALFSGQPLIILGATGPMLVFEEIVYTFCERVGLEYLSFRLWIGIWTMLFCLILVVTDASAMICYFTRFTEETFATLIAIIYIYEGFKKLFHILDDYPIH 114          
BLAST of slc4a-1 vs. Ensembl Nematostella
Match: EDO40610 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S6T5])

HSP 1 Score: 94.3597 bits (233), Expect = 9.420e-21
Identity = 69/170 (40.59%), Postives = 95/170 (55.88%), Query Frame = 2
Query: 2675 AMGPALLAVILIFMDQQITAVIVNRKENKLKKGSGYHXXXXXXXXXXXXXXXXGIPWFVAATVLSINHVMSLKKESENTAPGER-PVFLGCREQRVTGTIIFLVIGLSVFLTPL-LKRIPMAVLYGVFLFMGVASLKGVQLMQRISLFFMPAKYQPDYIFLRYVPLRRVH 3178
            A G      +L FMDQ I++ +VN   N+LKKGS +HLDLLVVAI+  + S  G+PW   A   S  HV +L    E    G    + +  RE R+T  I  ++IGLS+ + P  L  IP AVL G+FLF+ V SL   Q+ +R+ LF       P   ++R VP R++H
Sbjct:   95 ACGLGFCLSLLFFMDQNISSAMVNNPGNRLKKGSAFHLDLLVVAIINGILSAFGLPWIHGALPHSPLHVRALADVEERVDQGHVFDIIVKVRETRLTTLIAHILIGLSLLMLPTPLDYIPTAVLDGLFLFVAVTSLDDNQMFERLLLFVTEQSAYPPNHYIRRVPQRKMH 264          
BLAST of slc4a-1 vs. Ensembl Nematostella
Match: EDO40611 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S6T6])

HSP 1 Score: 75.485 bits (184), Expect = 9.683e-14
Identity = 72/281 (25.62%), Postives = 117/281 (41.64%), Query Frame = 2
Query: 1046 ETSNIMVGETDF--LNQMVVVFIRLKEAVILGELTEVPVPTRFVFVMLGP-QGSAVKNH-EIGRSMATLMSDDVFHDVAYKARNLDDLLAGIDEFLSNCTVLPPAEWDPSIRIEPPKSGPIARKVPSMPNGAQALLTASGDGRXXXXXXXXXXXXXXASVVNKLQPVEEESHADPTLRRTGRLFGGLIEDVKRKAPFYLSDFKDAI--HVQCF---ASFFFLYFACLTPIITFGGLLVQATGGYLGAIESILSGTIVGVVYSLFSGQPLTIMGSTGPVLVF 1861
            ET N +V   D   + Q  +   RL+ A  LG   +    T  V ++L P +    KN  E+GR+ ATL+SD  F     +A + ++ +  + E  S+ +         + R +P  +  + R      N    +                                +E S   P          G+ +D  R+ P YLSDFKD +  H   F   ++  FLYFAC+ P + FG L  + T G +   + ++S    G+ +SL  GQPL I+ +T P+ ++
Sbjct:  110 ETQNWLVAMADLPSIQQSHIAMSRLRHATNLGRTLQ---GTHLVVLILSPVKTKKTKNSLELGRTFATLLSDIDFRQSLLEAESKEEFVKVLAERKSDLS---------NNRNKPEINSKLVRSASKGFNPYHCVFN-----------------------------FQETSTMKPC--------RGIRDDFMRRMPHYLSDFKDGVVGHRTLFKLVSTVIFLYFACILPSVAFGVLNSKNTKGKMDVQKVLVSQVFGGLFFSLLGGQPLIILLTTAPLALY 341          
BLAST of slc4a-1 vs. Ensembl Medaka
Match: slc4a8 (electroneutral sodium bicarbonate exchanger 1 [Source:NCBI gene;Acc:101162907])

HSP 1 Score: 920.613 bits (2378), Expect = 0.000e+0
Identity = 539/1161 (46.43%), Postives = 717/1161 (61.76%), Query Frame = 2
Query:  125 DEPILDRG--FQFTHYHPSEDEIEDHRSQRALYIGVHMPPDXXXXXXXXXXXXXXXXXXXXXDKKDYLTEIAEDDTEKATDPSQHVMFLLGEDEDEE--THNLFCEMDELRLDDEGEPEWKETARWIKFEEDVEEGGERWSKPHVASLSLYSLFEVRNCITSAVNMFNVEANNFETIIEIILNKIVSEKKISPDQREKVKEMLQRKHVHLHERRHKSNAKGSQLPLIRSLADIGKKYSS-------KEVDKVQLQRRNSDYPTKFTRFDANXXXXXXXXXXXXXYVDKNRIDVDQCGSDNLASQKFDLHFFKKIPLGAETSNIMVGETDFLNQMVVVFIRLKEAVILGELTEVPVPTRFVFVMLGPQGSAVKNHEIGRSMATLMSDDVFHDVAYKARNLDDLLAGIDEFLSNCTVLPPAEWDPSIRIEPPKSGPIA--RKVPSMPNGAQALLTASGDGRXXXXXXXXXXXXXXASVVNKLQPVEEESHAD---PTLRRTGRLFGGLIEDVKRKAPFYLSDFKDAIHVQCFASFFFLYFACLTPIITFGGLLVQATGGYLGAIESILSGTIVGVVYSLFSGQPLTIMGSTGPVLVFESIVYNICERMRWDYLPFRLWIGVWIAAYLFLMVAFDLSALVRYITRFTEESFAALIALIFMVEAFKKLFLIVDYYPIDTRWNIDMIKNRTCECF----PRNATAMDAFFQKNNKPSNVYMPPMLYPVPLNSSVIDIVNNIDWQNISNYHFTWDYKKYRLICTKWGGIWTGSGCGNY--FIPDVFFFSCLLFIGTFVLSYGLKMMRNAQFFPNWVRSLISDFAVMIAISSMTLLDWSLGFHTPKLNVPAKFEPTLGYKMRGWVIPALGKNPWWTIIIAMGPALLAVILIFMDQQITAVIVNRKENKLKKGSGYHXXXXXXXXXXXXXXXXGIPWFVAATVLSINHVMSLKKESENTAPGERPVFLGCREQRVTGTIIFLVIGLSVFLTPLLKRIPMAVLYGVFLFMGVASLKGVQLMQRISLFFMPAKYQPDYIFLRYVPLRRVHXXXXXXXXXXXXXXXXXXXNVMSICFPIMVLALCFVRKGLEYLFTYNELKWLDDIMPNHKKPPQDDNENDIEKCGSTELIKMTETNLEFNSSTNKVIRSNDSGINISEEMGKTAIWKQLSG 3541
            +E ++D+G      + H  ++E+E H+   ALY+GV M      Q    R  R   S+  + D++       + +  +A  PSQ V F+LG +ED E  +H LF E+DE+ + D  + EWKETARW+KFEEDVE+GGERWSKP+VA+LSL+SLFE+R+CI +   + ++ A+  E I +++L+   +  ++    R +V+E L ++H       H++  K + +P++RS+ +  +K S             V  Q   +  P K                 +    D +++D+           K DLHF KKIP GAE SN++VG  DFL + VV F+RL  AV+L  LTEVP+PTRF+F++LGP G A + HEIGRSMAT+M+D++FH+VAYKA++  DLLAGIDEFL   TVLPP EWDPSIRIEPPKS P    RK+P +PNG                                   VEEE HA+   P L+RTGRLFGGLI D+KRK PFYLSDFKD + +QC ASF FLY AC++P+ITFGGLL +AT G++ AIES+   ++ G+VYSLF+GQPLTI+GSTGPVLVFE I++  C+     YL  R  IG+W A    ++VA D S+LV YITRFTEE+FAALI LIF+ EA +KLF + + YP +   ++D +    C C     PRN T +  +  +N   S+V                       W N++              C    G + G+ CG++  + PDV F+S +LF  TF +S  LK  + +++FP  VRS+ISDFAV + I  M LLD+ +G  T KL VP+KF+PT     RGW I  LG NPWWT I+A  PALL  ILIFMDQQITAVI+NRKE+KL KG GYHLDLL+V +++ V SI+G+PWFVAATVLSI+HV SLK ESE+ APGE+P FLG REQR+TG +IFL++G SVF+T  L+ IPM VLYGVFL+MG +SLKG+Q   R+ LF MPAK+QPD+I+LR+VPLR+VHLFT+ Q+  LVLLWVIKT    +I FP+MVLAL F+RK L+  F+  EL +LDD+MP  KK   DD              KM E               + S INIS+EM KT +WK L+ 
Sbjct:   20 EEVVVDQGGMSSVMNIHYEKEELEGHK---ALYVGVRM------QRQSHRHHRPHGSRHRKRDRRAGSIATQQSEDSEANTPSQRVQFILGTEEDAEHVSHELFTELDEICVKDGKDAEWKETARWLKFEEDVEDGGERWSKPYVATLSLHSLFELRSCIINGSVLLDMHADCIEEIADMVLDHQEASHELDDTVRVRVREALLKRH------HHQNMKKKNLIPIVRSITEGTRKQSEAFLSATLHPAGSVTCQPPPASEPAK-----------------NVAGQDSSQVDLS----------KVDLHFMKKIPEGAEASNVLVGVLDFLERPVVAFVRLSPAVVLTGLTEVPIPTRFLFILLGPDGKAQQYHEIGRSMATIMTDEIFHNVAYKAKDRSDLLAGIDEFLDQVTVLPPGEWDPSIRIEPPKSVPSQEKRKMPGVPNGTPC-------------------------------EVEEELHAEQHGPELQRTGRLFGGLILDIKRKVPFYLSDFKDGLSLQCVASFLFLYCACMSPVITFGGLLGEATEGHISAIESLFGASMTGMVYSLFAGQPLTILGSTGPVLVFEKILFKFCKEYDLSYLSLRTCIGLWTAFLCLILVATDASSLVCYITRFTEEAFAALICLIFIFEALEKLFYLGEQYPYNAHSDLDRLTLAHCRCAEPDNPRNET-LKMWSDRNISASSV----------------------SWDNLTVKE-----------CISLHGQFVGTACGHHGPYTPDVLFWSAILFFSTFFMSASLKQFKTSRYFPTKVRSVISDFAVFLTIVIMVLLDFVIGVQTQKLKVPSKFQPT--RDDRGWFISPLGPNPWWTAIVACFPALLCTILIFMDQQITAVIINRKEHKLLKGCGYHLDLLMVGVMLAVCSIMGLPWFVAATVLSISHVNSLKLESESAAPGEQPRFLGIREQRLTGLLIFLLMGCSVFMTKALQFIPMPVLYGVFLYMGASSLKGIQFFDRLKLFGMPAKHQPDFIYLRHVPLRKVHLFTVTQLTCLVLLWVIKTSPA-AIVFPMMVLALVFIRKLLDLCFSKRELSYLDDLMPEWKKKTLDDASK-----------KMQEV-------------CDPSDINISDEMSKTTMWKSLNS 1046          
BLAST of slc4a-1 vs. Ensembl Medaka
Match: slc4a10a (sodium-driven chloride bicarbonate exchanger [Source:NCBI gene;Acc:101167104])

HSP 1 Score: 906.746 bits (2342), Expect = 0.000e+0
Identity = 537/1158 (46.37%), Postives = 733/1158 (63.30%), Query Frame = 2
Query:  110 DITVGDEPILDRGFQFTHYHPS--EDEIEDHRSQRALYIGVHMPPDXXXXXXXXXXXXXXXXXXXXXDKKDYLTEIAEDDTEKAT--DPSQHVMFLLG---EDEDEETHNLFCEMDELRLDDEGEPEWKETARWIKFEEDVEEGGERWSKPHVASLSLYSLFEVRNCITSAVNMFNVEANNFETIIEIILNKIVSEKKISPDQREKVKEMLQRKHVHLHERRHKSNAKGSQLPLIRSLADIGKKYSS-KEVDKVQLQRRNSDYPTKFTRFDANXXXXXXXXXXXXXYVDKNRIDVDQCGSDNLASQKFDLHFFKKIPLGAETSNIMVGETDFLNQMVVVFIRLKEAVILGELTEVPVPTRFVFVMLGPQGSAVKNHEIGRSMATLMSDDVFHDVAYKARNLDDLLAGIDEFLSNCTVLPPAEWDPSIRIEPPKSGPIA--RKVPSMPNGAQALLTASGDGRXXXXXXXXXXXXXXASVVNKLQPVEEESHADPTLRRTGRLFGGLIEDVKRKAPFYLSDFKDAIHVQCFASFFFLYFACLTPIITFGGLLVQATGGYLGAIESILSGTIVGVVYSLFSGQPLTIMGSTGPVLVFESIVYNICERMRWDYLPFRLWIGVWIAAYLFLMVAFDLSALVRYITRFTEESFAALIALIFMVEAFKKLFLIVDYYPIDTRWNIDMIKNRTCECFPRNATAMDAFFQKNNKPSNVYMPPMLYPVPLNSSVIDIVNNIDWQNISNYHFTWDYKKYRLICTKWGGIWTGSGCGNY--FIPDVFFFSCLLFIGTFVLSYGLKMMRNAQFFPNWVRSLISDFAVMIAISSMTLLDWSLGFHTPKLNVPAKFEPTLGYKMRGWVIPALGKNPWWTIIIAMGPALLAVILIFMDQQITAVIVNRKENKLKKGSGYHXXXXXXXXXXXXXXXXGIPWFVAATVLSINHVMSLKKESENTAPGERPVFLGCREQRVTGTIIFLVIGLSVFLTPLLKRIPMAVLYGVFLFMGVASLKGVQLMQRISLFFMPAKYQPDYIFLRYVPLRRVHXXXXXXXXXXXXXXXXXXXNVMSICFPIMVLALCFVRKGLEYLFTYNELKWLDDIMPNHKKPPQDDNENDIEKCGSTELIKMTETNLEFNSSTNKVIRSNDSGINISEEMGKTA---IWKQLS 3538
            D+   +E ++DRG   +  + +  ++E+E HR+   LYIGVH+P   + + + +R R H    + +  ++D  T+   +    +T   P+Q V FLLG    DED   H LF E+DE+ L +  + EW+ETARW+KFEEDVE+GGERWSKP+VA+LSL+SLFE+R+CI +   M ++ AN+ E I +++L++      + PD R +V+E L ++H   H + HK  A  +++P++RS ADIGKK S    +DK          P+                      +++ + DV +  S ++   K DLHF KKIP GAE SN++VGE +FL++ VV F+RL  AV+L  L EVP+ TRF+F++LGP G   + HEIGRS+ATLM+D++FHDVAYKA++  DL+AGIDEFL   TVLPP EWDPSIRIEPPK+ P    RK+P +PNG   L  +   G                             H  P L+RTG+ FGG I D+KRKAP YLSD+ DAI +QC ASF FLY AC++P+ITFGGLL +AT G + AIES+   ++ G+ YSLF+GQPLTI+GSTGPVLVFE I++  C+     YL  R  IG+W A    L+VA D S+LV YITRFTEE+FAALI +IF+ EA +KL  +  +YPI+   NI  +    C C            ++ + PSN                 + +   +  NI+     W        C K  G + G  CG +  FIPDV F+  +LF  T  +S  LK  + +++FP  VR++ISDFAV I I +M L+D++LG  +PKL VP KF+PT     RGWVI  +G NPWWT II + PALL  ILIFMDQQITAVI+NRKE+KLKKG GYHLDL VV +++ V S++G+PWFVAATVLSI+HV SLK ESE +APGE+P FLG REQR TG +IF ++G SVF+T +LK IPM VLYGVFL+MG +SL+G+Q   R+ LF MPAK+QPD+I+LR+VPLR+VHLFTI+Q+  L+LLWVIKT    +I FP+MVLAL F+RK L+++F+  EL WLDD++P  KK   +D E + E     E   + +  LE +       +S+ + +NI++EM K +   +WK +S
Sbjct:   24 DVRTDEEAVVDRGGTRSMLNTNFEKEELEGHRT---LYIGVHVP---LGRRSHRRHRHHGHRHRKRSKERDSSTDDGRESPSHSTANTPAQRVQFLLGTEDADEDHIPHALFTELDEICLREGEDAEWRETARWLKFEEDVEDGGERWSKPYVATLSLHSLFELRSCIMNGTVMLDMRANSLEEIADMVLDQHELSGPLGPDARNRVREALLKQH---HHQNHKKLA--NRIPIVRSFADIGKKQSEPHSMDKNGQTVSPPSQPS----------------------INEGKQDVSRENS-SVDFSKIDLHFMKKIPPGAEASNVLVGELEFLDRPVVAFVRLSPAVLLNGLAEVPITTRFLFILLGPLGKGPQYHEIGRSIATLMTDEIFHDVAYKAKDRSDLVAGIDEFLDQVTVLPPGEWDPSIRIEPPKNVPSQEKRKIPPVPNGVTDLGESPEPG----------------------------GHGGPELQRTGKFFGGFILDIKRKAPHYLSDYTDAISLQCLASFLFLYCACMSPVITFGGLLGEATEGRVSAIESLFGASMTGIAYSLFAGQPLTILGSTGPVLVFEKILFKFCKEYGLSYLSLRACIGLWTAFLCLLLVATDASSLVCYITRFTEEAFAALICIIFIYEALEKLVHLGVHYPINKNNNIQKLTQYWCLC------------EEPHSPSN-----------------ETLRFWEDSNITASEVNWTSLDVNE-CEKLHGHFEGRACGPHGPFIPDVLFWCVILFFSTVFMSAFLKEFKTSRYFPTKVRAIISDFAVFITILTMVLVDYALGIPSPKLQVPNKFKPT--RDDRGWVINPVGPNPWWTTIITVIPALLCTILIFMDQQITAVIINRKEHKLKKGCGYHLDLFVVGVMLGVCSVMGLPWFVAATVLSISHVNSLKLESECSAPGEQPKFLGIREQRFTGLMIFTLMGCSVFMTSVLKFIPMPVLYGVFLYMGASSLRGIQFFDRLRLFGMPAKHQPDFIYLRHVPLRKVHLFTIVQLSCLILLWVIKTSRA-AIVFPMMVLALVFIRKLLDFVFSKRELSWLDDLIPEWKKKKLEDAEEEEEHSIIAEEEGIVQVPLEGH------YKSDPATVNITDEMSKGSFGNVWKSVS 1080          
BLAST of slc4a-1 vs. Ensembl Medaka
Match: slc4a10a (sodium-driven chloride bicarbonate exchanger [Source:NCBI gene;Acc:101167104])

HSP 1 Score: 905.975 bits (2340), Expect = 0.000e+0
Identity = 537/1158 (46.37%), Postives = 733/1158 (63.30%), Query Frame = 2
Query:  110 DITVGDEPILDRGFQFTHYHPS--EDEIEDHRSQRALYIGVHMPPDXXXXXXXXXXXXXXXXXXXXXDKKDYLTEIAEDDTEKAT--DPSQHVMFLLG---EDEDEETHNLFCEMDELRLDDEGEPEWKETARWIKFEEDVEEGGERWSKPHVASLSLYSLFEVRNCITSAVNMFNVEANNFETIIEIILNKIVSEKKISPDQREKVKEMLQRKHVHLHERRHKSNAKGSQLPLIRSLADIGKKYSS-KEVDKVQLQRRNSDYPTKFTRFDANXXXXXXXXXXXXXYVDKNRIDVDQCGSDNLASQKFDLHFFKKIPLGAETSNIMVGETDFLNQMVVVFIRLKEAVILGELTEVPVPTRFVFVMLGPQGSAVKNHEIGRSMATLMSDDVFHDVAYKARNLDDLLAGIDEFLSNCTVLPPAEWDPSIRIEPPKSGPIA--RKVPSMPNGAQALLTASGDGRXXXXXXXXXXXXXXASVVNKLQPVEEESHADPTLRRTGRLFGGLIEDVKRKAPFYLSDFKDAIHVQCFASFFFLYFACLTPIITFGGLLVQATGGYLGAIESILSGTIVGVVYSLFSGQPLTIMGSTGPVLVFESIVYNICERMRWDYLPFRLWIGVWIAAYLFLMVAFDLSALVRYITRFTEESFAALIALIFMVEAFKKLFLIVDYYPIDTRWNIDMIKNRTCECFPRNATAMDAFFQKNNKPSNVYMPPMLYPVPLNSSVIDIVNNIDWQNISNYHFTWDYKKYRLICTKWGGIWTGSGCGNY--FIPDVFFFSCLLFIGTFVLSYGLKMMRNAQFFPNWVRSLISDFAVMIAISSMTLLDWSLGFHTPKLNVPAKFEPTLGYKMRGWVIPALGKNPWWTIIIAMGPALLAVILIFMDQQITAVIVNRKENKLKKGSGYHXXXXXXXXXXXXXXXXGIPWFVAATVLSINHVMSLKKESENTAPGERPVFLGCREQRVTGTIIFLVIGLSVFLTPLLKRIPMAVLYGVFLFMGVASLKGVQLMQRISLFFMPAKYQPDYIFLRYVPLRRVHXXXXXXXXXXXXXXXXXXXNVMSICFPIMVLALCFVRKGLEYLFTYNELKWLDDIMPNHKKPPQDDNENDIEKCGSTELIKMTETNLEFNSSTNKVIRSNDSGINISEEMGKTA---IWKQLS 3538
            D+   +E ++DRG   +  + +  ++E+E HR+   LYIGVH+P   + + + +R R H    + +  ++D  T+   +    +T   P+Q V FLLG    DED   H LF E+DE+ L +  + EW+ETARW+KFEEDVE+GGERWSKP+VA+LSL+SLFE+R+CI +   M ++ AN+ E I +++L++      + PD R +V+E L ++H   H + HK  A  +++P++RS ADIGKK S    +DK          P+                      +++ + DV +  S ++   K DLHF KKIP GAE SN++VGE +FL++ VV F+RL  AV+L  L EVP+ TRF+F++LGP G   + HEIGRS+ATLM+D++FHDVAYKA++  DL+AGIDEFL   TVLPP EWDPSIRIEPPK+ P    RK+P +PNG   L  +   G                             H  P L+RTG+ FGG I D+KRKAP YLSD+ DAI +QC ASF FLY AC++P+ITFGGLL +AT G + AIES+   ++ G+ YSLF+GQPLTI+GSTGPVLVFE I++  C+     YL  R  IG+W A    L+VA D S+LV YITRFTEE+FAALI +IF+ EA +KL  +  +YPI+   NI  +    C C            ++ + PSN                 + +   +  NI+     W        C K  G + G  CG +  FIPDV F+  +LF  T  +S  LK  + +++FP  VR++ISDFAV I I +M L+D++LG  +PKL VP KF+PT     RGWVI  +G NPWWT II + PALL  ILIFMDQQITAVI+NRKE+KLKKG GYHLDL VV +++ V S++G+PWFVAATVLSI+HV SLK ESE +APGE+P FLG REQR TG +IF ++G SVF+T +LK IPM VLYGVFL+MG +SL+G+Q   R+ LF MPAK+QPD+I+LR+VPLR+VHLFTI+Q+  L+LLWVIKT    +I FP+MVLAL F+RK L+++F+  EL WLDD++P  KK   +D E + E     E   + +  LE +       +S+ + +NI++EM K +   +WK +S
Sbjct:   24 DVRTDEEAVVDRGGTRSMLNTNFEKEELEGHRT---LYIGVHVP---LGRRSHRRHRHHGHRHRKRSKERDSSTDDGRESPSHSTANTPAQRVQFLLGTEDADEDHIPHALFTELDEICLREGEDAEWRETARWLKFEEDVEDGGERWSKPYVATLSLHSLFELRSCIMNGTVMLDMRANSLEEIADMVLDQHELSGPLGPDARNRVREALLKQH---HHQNHKKLA--NRIPIVRSFADIGKKQSEPHSMDKNGQTVSPPSQPS----------------------INEGKQDVSRENS-SVDFSKIDLHFMKKIPPGAEASNVLVGELEFLDRPVVAFVRLSPAVLLNGLAEVPITTRFLFILLGPLGKGPQYHEIGRSIATLMTDEIFHDVAYKAKDRSDLVAGIDEFLDQVTVLPPGEWDPSIRIEPPKNVPSQEKRKIPPVPNGVTDLGESPEPG----------------------------GHGGPELQRTGKFFGGFILDIKRKAPHYLSDYTDAISLQCLASFLFLYCACMSPVITFGGLLGEATEGRVSAIESLFGASMTGIAYSLFAGQPLTILGSTGPVLVFEKILFKFCKEYGLSYLSLRACIGLWTAFLCLLLVATDASSLVCYITRFTEEAFAALICIIFIYEALEKLVHLGVHYPINKNNNIQKLTQYWCLC------------EEPHSPSN-----------------ETLRFWEDSNITASEVNWTSLDVNE-CEKLHGHFEGRACGPHGPFIPDVLFWCVILFFSTVFMSAFLKEFKTSRYFPTKVRAIISDFAVFITILTMVLVDYALGIPSPKLQVPNKFKPT--RDDRGWVINPVGPNPWWTTIITVIPALLCTILIFMDQQITAVIINRKEHKLKKGCGYHLDLFVVGVMLGVCSVMGLPWFVAATVLSISHVNSLKLESECSAPGEQPKFLGIREQRFTGLMIFTLMGCSVFMTSVLKFIPMPVLYGVFLYMGASSLRGIQFFDRLRLFGMPAKHQPDFIYLRHVPLRKVHLFTIVQLSCLILLWVIKTSRA-AIVFPMMVLALVFIRKLLDFVFSKRELSWLDDLIPEWKKKKLEDAEEEEEHSIIAEEEGIVQVPLEGH------YKSDPATVNITDEMSKGSFGNVWKSVS 1080          
BLAST of slc4a-1 vs. Ensembl Medaka
Match: slc4a10a (sodium-driven chloride bicarbonate exchanger [Source:NCBI gene;Acc:101167104])

HSP 1 Score: 905.975 bits (2340), Expect = 0.000e+0
Identity = 537/1158 (46.37%), Postives = 733/1158 (63.30%), Query Frame = 2
Query:  110 DITVGDEPILDRGFQFTHYHPS--EDEIEDHRSQRALYIGVHMPPDXXXXXXXXXXXXXXXXXXXXXDKKDYLTEIAEDDTEKAT--DPSQHVMFLLG---EDEDEETHNLFCEMDELRLDDEGEPEWKETARWIKFEEDVEEGGERWSKPHVASLSLYSLFEVRNCITSAVNMFNVEANNFETIIEIILNKIVSEKKISPDQREKVKEMLQRKHVHLHERRHKSNAKGSQLPLIRSLADIGKKYSS-KEVDKVQLQRRNSDYPTKFTRFDANXXXXXXXXXXXXXYVDKNRIDVDQCGSDNLASQKFDLHFFKKIPLGAETSNIMVGETDFLNQMVVVFIRLKEAVILGELTEVPVPTRFVFVMLGPQGSAVKNHEIGRSMATLMSDDVFHDVAYKARNLDDLLAGIDEFLSNCTVLPPAEWDPSIRIEPPKSGPIA--RKVPSMPNGAQALLTASGDGRXXXXXXXXXXXXXXASVVNKLQPVEEESHADPTLRRTGRLFGGLIEDVKRKAPFYLSDFKDAIHVQCFASFFFLYFACLTPIITFGGLLVQATGGYLGAIESILSGTIVGVVYSLFSGQPLTIMGSTGPVLVFESIVYNICERMRWDYLPFRLWIGVWIAAYLFLMVAFDLSALVRYITRFTEESFAALIALIFMVEAFKKLFLIVDYYPIDTRWNIDMIKNRTCECFPRNATAMDAFFQKNNKPSNVYMPPMLYPVPLNSSVIDIVNNIDWQNISNYHFTWDYKKYRLICTKWGGIWTGSGCGNY--FIPDVFFFSCLLFIGTFVLSYGLKMMRNAQFFPNWVRSLISDFAVMIAISSMTLLDWSLGFHTPKLNVPAKFEPTLGYKMRGWVIPALGKNPWWTIIIAMGPALLAVILIFMDQQITAVIVNRKENKLKKGSGYHXXXXXXXXXXXXXXXXGIPWFVAATVLSINHVMSLKKESENTAPGERPVFLGCREQRVTGTIIFLVIGLSVFLTPLLKRIPMAVLYGVFLFMGVASLKGVQLMQRISLFFMPAKYQPDYIFLRYVPLRRVHXXXXXXXXXXXXXXXXXXXNVMSICFPIMVLALCFVRKGLEYLFTYNELKWLDDIMPNHKKPPQDDNENDIEKCGSTELIKMTETNLEFNSSTNKVIRSNDSGINISEEMGKTA---IWKQLS 3538
            D+   +E ++DRG   +  + +  ++E+E HR+   LYIGVH+P   + + + +R R H    + +  ++D  T+   +    +T   P+Q V FLLG    DED   H LF E+DE+ L +  + EW+ETARW+KFEEDVE+GGERWSKP+VA+LSL+SLFE+R+CI +   M ++ AN+ E I +++L++      + PD R +V+E L ++H   H + HK  A  +++P++RS ADIGKK S    +DK          P+                      +++ + DV +  S ++   K DLHF KKIP GAE SN++VGE +FL++ VV F+RL  AV+L  L EVP+ TRF+F++LGP G   + HEIGRS+ATLM+D++FHDVAYKA++  DL+AGIDEFL   TVLPP EWDPSIRIEPPK+ P    RK+P +PNG   L  +   G                             H  P L+RTG+ FGG I D+KRKAP YLSD+ DAI +QC ASF FLY AC++P+ITFGGLL +AT G + AIES+   ++ G+ YSLF+GQPLTI+GSTGPVLVFE I++  C+     YL  R  IG+W A    L+VA D S+LV YITRFTEE+FAALI +IF+ EA +KL  +  +YPI+   NI  +    C C            ++ + PSN                 + +   +  NI+     W        C K  G + G  CG +  FIPDV F+  +LF  T  +S  LK  + +++FP  VR++ISDFAV I I +M L+D++LG  +PKL VP KF+PT     RGWVI  +G NPWWT II + PALL  ILIFMDQQITAVI+NRKE+KLKKG GYHLDL VV +++ V S++G+PWFVAATVLSI+HV SLK ESE +APGE+P FLG REQR TG +IF ++G SVF+T +LK IPM VLYGVFL+MG +SL+G+Q   R+ LF MPAK+QPD+I+LR+VPLR+VHLFTI+Q+  L+LLWVIKT    +I FP+MVLAL F+RK L+++F+  EL WLDD++P  KK   +D E + E     E   + +  LE +       +S+ + +NI++EM K +   +WK +S
Sbjct:   22 DVRTDEEAVVDRGGTRSMLNTNFEKEELEGHRT---LYIGVHVP---LGRRSHRRHRHHGHRHRKRSKERDSSTDDGRESPSHSTANTPAQRVQFLLGTEDADEDHIPHALFTELDEICLREGEDAEWRETARWLKFEEDVEDGGERWSKPYVATLSLHSLFELRSCIMNGTVMLDMRANSLEEIADMVLDQHELSGPLGPDARNRVREALLKQH---HHQNHKKLA--NRIPIVRSFADIGKKQSEPHSMDKNGQTVSPPSQPS----------------------INEGKQDVSRENS-SVDFSKIDLHFMKKIPPGAEASNVLVGELEFLDRPVVAFVRLSPAVLLNGLAEVPITTRFLFILLGPLGKGPQYHEIGRSIATLMTDEIFHDVAYKAKDRSDLVAGIDEFLDQVTVLPPGEWDPSIRIEPPKNVPSQEKRKIPPVPNGVTDLGESPEPG----------------------------GHGGPELQRTGKFFGGFILDIKRKAPHYLSDYTDAISLQCLASFLFLYCACMSPVITFGGLLGEATEGRVSAIESLFGASMTGIAYSLFAGQPLTILGSTGPVLVFEKILFKFCKEYGLSYLSLRACIGLWTAFLCLLLVATDASSLVCYITRFTEEAFAALICIIFIYEALEKLVHLGVHYPINKNNNIQKLTQYWCLC------------EEPHSPSN-----------------ETLRFWEDSNITASEVNWTSLDVNE-CEKLHGHFEGRACGPHGPFIPDVLFWCVILFFSTVFMSAFLKEFKTSRYFPTKVRAIISDFAVFITILTMVLVDYALGIPSPKLQVPNKFKPT--RDDRGWVINPVGPNPWWTTIITVIPALLCTILIFMDQQITAVIINRKEHKLKKGCGYHLDLFVVGVMLGVCSVMGLPWFVAATVLSISHVNSLKLESECSAPGEQPKFLGIREQRFTGLMIFTLMGCSVFMTSVLKFIPMPVLYGVFLYMGASSLRGIQFFDRLRLFGMPAKHQPDFIYLRHVPLRKVHLFTIVQLSCLILLWVIKTSRA-AIVFPMMVLALVFIRKLLDFVFSKRELSWLDDLIPEWKKKKLEDAEEEEEHSIIAEEEGIVQVPLEGH------YKSDPATVNITDEMSKGSFGNVWKSVS 1078          
BLAST of slc4a-1 vs. Ensembl Medaka
Match: slc4a10a (sodium-driven chloride bicarbonate exchanger [Source:NCBI gene;Acc:101167104])

HSP 1 Score: 903.279 bits (2333), Expect = 0.000e+0
Identity = 515/1072 (48.04%), Postives = 689/1072 (64.27%), Query Frame = 2
Query:  203 QRALYIGVHMPPDXXXXXXXXXXXXXXXXXXXXXDKKDYLTEIAEDDTEKATDPSQHVMFLLG---EDEDEETHNLFCEMDELRLDDEGEPEWKETARWIKFEEDVEEGGERWSKPHVASLSLYSLFEVRNCITSAVNMFNVEANNFETIIEIILNKIVSEKKISPDQREKVKEMLQRKHVHLHERRHKSNAKGSQLPLIRSLADIGKKYSS-KEVDKVQLQRRNSDYPTKFTRFDANXXXXXXXXXXXXXYVDKNRIDVDQCGSDNLASQKFDLHFFKKIPLGAETSNIMVGETDFLNQMVVVFIRLKEAVILGELTEVPVPTRFVFVMLGPQGSAVKNHEIGRSMATLMSDDVFHDVAYKARNLDDLLAGIDEFLSNCTVLPPAEWDPSIRIEPPKSGPIA--RKVPSMPNGAQALLTASGDGRXXXXXXXXXXXXXXASVVNKLQPVEEESHADPTLRRTGRLFGGLIEDVKRKAPFYLSDFKDAIHVQCFASFFFLYFACLTPIITFGGLLVQATGGYLGAIESILSGTIVGVVYSLFSGQPLTIMGSTGPVLVFESIVYNICERMRWDYLPFRLWIGVWIAAYLFLMVAFDLSALVRYITRFTEESFAALIALIFMVEAFKKLFLIVDYYPIDTRWNIDMIKNRTCECFPRNATAMDAFFQKNNKPSNVYMPPMLYPVPLNSSVIDIVNNIDWQNISNYHFTWDYKKYRLICTKWGGIWTGSGCGNY--FIPDVFFFSCLLFIGTFVLSYGLKMMRNAQFFPNWVRSLISDFAVMIAISSMTLLDWSLGFHTPKLNVPAKFEPTLGYKMRGWVIPALGKNPWWTIIIAMGPALLAVILIFMDQQITAVIVNRKENKLKKGSGYHXXXXXXXXXXXXXXXXGIPWFVAATVLSINHVMSLKKESENTAPGERPVFLGCREQRVTGTIIFLVIGLSVFLTPLLKRIPMAVLYGVFLFMGVASLKGVQLMQRISLFFMPAKYQPDYIFLRYVPLRRVHXXXXXXXXXXXXXXXXXXXNVMSICFPIMVLALCFVRKGLEYLFTYNELKWLDDIMPNHKKPPQDDNENDIE 3394
             R LYIGVH+P   + + + +R R H    + +  ++D  T+   +       P+Q V FLLG    DED   H LF E+DE+ L +  + EW+ETARW+KFEEDVE+GGERWSKP+VA+LSL+SLFE+R+CI +   M ++ AN+ E I +++L++      + PD R +V+E L ++H   H + HK  A  +++P++RS ADIGKK S    +DK          P+                      +++ + DV +  S ++   K DLHF KKIP GAE SN++VGE +FL++ VV F+RL  AV+L  L EVP+ TRF+F++LGP G   + HEIGRS+ATLM+D++FHDVAYKA++  DL+AGIDEFL   TVLPP EWDPSIRIEPPK+ P    RK+P +PNG   L  +   G                             H  P L+RTG+ FGG I D+KRKAP YLSD+ DAI +QC ASF FLY AC++P+ITFGGLL +AT G + AIES+   ++ G+ YSLF+GQPLTI+GSTGPVLVFE I++  C+     YL  R  IG+W A    L+VA D S+LV YITRFTEE+FAALI +IF+ EA +KL  +  +YPI+   NI  +    C C            ++ + PSN                 + +   +  NI+     W        C K  G + G  CG +  FIPDV F+  +LF  T  +S  LK  + +++FP  VR++ISDFAV I I +M L+D++LG  +PKL VP KF+PT     RGWVI  +G NPWWT II + PALL  ILIFMDQQITAVI+NRKE+KLKKG GYHLDL VV +++ V S++G+PWFVAATVLSI+HV SLK ESE +APGE+P FLG REQR TG +IF ++G SVF+T +LK IPM VLYGVFL+MG +SL+G+Q   R+ LF MPAK+QPD+I+LR+VPLR+VHLFTI+Q+  L+LLWVIKT    +I FP+MVLAL F+RK L+++F+  EL WLDD++P  KK   +D E +++
Sbjct:   15 HRTLYIGVHVP---LGRRSHRRHRHHGHRHRKRSKERDSSTDDGRESPSHTNTPAQRVQFLLGTEDADEDHIPHALFTELDEICLREGEDAEWRETARWLKFEEDVEDGGERWSKPYVATLSLHSLFELRSCIMNGTVMLDMRANSLEEIADMVLDQHELSGPLGPDARNRVREALLKQH---HHQNHKKLA--NRIPIVRSFADIGKKQSEPHSMDKNGQTVSPPSQPS----------------------INEGKQDVSRENS-SVDFSKIDLHFMKKIPPGAEASNVLVGELEFLDRPVVAFVRLSPAVLLNGLAEVPITTRFLFILLGPLGKGPQYHEIGRSIATLMTDEIFHDVAYKAKDRSDLVAGIDEFLDQVTVLPPGEWDPSIRIEPPKNVPSQEKRKIPPVPNGVTDLGESPEPG----------------------------GHGGPELQRTGKFFGGFILDIKRKAPHYLSDYTDAISLQCLASFLFLYCACMSPVITFGGLLGEATEGRVSAIESLFGASMTGIAYSLFAGQPLTILGSTGPVLVFEKILFKFCKEYGLSYLSLRACIGLWTAFLCLLLVATDASSLVCYITRFTEEAFAALICIIFIYEALEKLVHLGVHYPINKNNNIQKLTQYWCLC------------EEPHSPSN-----------------ETLRFWEDSNITASEVNWTSLDVNE-CEKLHGHFEGRACGPHGPFIPDVLFWCVILFFSTVFMSAFLKEFKTSRYFPTKVRAIISDFAVFITILTMVLVDYALGIPSPKLQVPNKFKPT--RDDRGWVINPVGPNPWWTTIITVIPALLCTILIFMDQQITAVIINRKEHKLKKGCGYHLDLFVVGVMLGVCSVMGLPWFVAATVLSISHVNSLKLESECSAPGEQPKFLGIREQRFTGLMIFTLMGCSVFMTSVLKFIPMPVLYGVFLYMGASSLRGIQFFDRLRLFGMPAKHQPDFIYLRHVPLRKVHLFTIVQLSCLILLWVIKTSRA-AIVFPMMVLALVFIRKLLDFVFSKRELSWLDDLIPEWKKKKLEDAEEEVQ 994          
BLAST of slc4a-1 vs. Planmine SMEST
Match: SMESG000024335.1 (SMESG000024335.1)

HSP 1 Score: 2298.09 bits (5954), Expect = 0.000e+0
Identity = 1228/1230 (99.84%), Postives = 1229/1230 (99.92%), Query Frame = 2
Query:  107 MDITVGDEPILDRGFQFTHYHPSEDEIEDHRSQRALYIGVHMPPDXXXXXXXXXXXXXXXXXXXXXDKKDYLTEIAEDDTEKATDPSQHVMFLLGEDEDEETHNLFCEMDELRLDDEGEPEWKETARWIKFEEDVEEGGERWSKPHVASLSLYSLFEVRNCITSAVNMFNVEANNFETIIEIILNKIVSEKKISPDQREKVKEMLQRKHVHLHERRHKSNAKGSQLPLIRSLADIGKKYSSKEVDKVQLQRRNSDYPTKFTRFDANXXXXXXXXXXXXXYVDKNRIDVDQCGSDNLASQKFDLHFFKKIPLGAETSNIMVGETDFLNQMVVVFIRLKEAVILGELTEVPVPTRFVFVMLGPQGSAVKNHEIGRSMATLMSDDVFHDVAYKARNLDDLLAGIDEFLSNCTVLPPAEWDPSIRIEPPKSGPIARKVPSMPNGAQALLTASGDGRXXXXXXXXXXXXXXASVVNKLQPVEEESHADPTLRRTGRLFGGLIEDVKRKAPFYLSDFKDAIHVQCFASFFFLYFACLTPIITFGGLLVQATGGYLGAIESILSGTIVGVVYSLFSGQPLTIMGSTGPVLVFESIVYNICERMRWDYLPFRLWIGVWIAAYLFLMVAFDLSALVRYITRFTEESFAALIALIFMVEAFKKLFLIVDYYPIDTRWNIDMIKNRTCECFPRNATAMDAFFQKNNKPSNVYMPPMLYPVPLNSSVIDIVNNIDWQNISNYHFTWDYKKYRLICTKWGGIWTGSGCGNYFIPDVFFFSCLLFIGTFVLSYGLKMMRNAQFFPNWVRSLISDFAVMIAISSMTLLDWSLGFHTPKLNVPAKFEPTLGYKMRGWVIPALGKNPWWTIIIAMGPALLAVILIFMDQQITAVIVNRKENKLKKGSGYHXXXXXXXXXXXXXXXXGIPWFVAATVLSINHVMSLKKESENTAPGERPVFLGCREQRVTGTIIFLVIGLSVFLTPLLKRIPMAVLYGVFLFMGVASLKGVQLMQRISLFFMPAKYQPDYIFLRYVPLRRVHXXXXXXXXXXXXXXXXXXXNVMSICFPIMVLALCFVRKGLEYLFTYNELKWLDDIMPNHKKPPQDDNENDIEKCGSTELIKMTETNLEFNSSTNKVIRSNDSGINISEEMGKTAIWKQLSGGTXXXXXXXXXXXXXXXXXXDRSGNKDMESGDQGNSDNSHVQPLLNDSRESGRDNKHHYMTTPEIVVNPPSARESPELKHQNPKV 3796
            MDITVGDEPILDRGFQFTHYHPSEDEIEDHRSQRALYIGVHMPPDRIHQPTRQRRRRHKKSKQGQHDKKDYLTEIAEDDTEKATDPSQHVMFLLGEDEDEETHNLFCEMDELRLDDEGEPEWKETARWIKFEEDVEEGGERWSKPHVASLSLYSLFEVRNCITSAVNMFNVEANNFETIIEIILNKIVSEKKISPDQREKVKEMLQRKHVHLHERRHKSNAKGSQLPLIRSLADIGKKYSSKEVDKVQLQRRNSDYPTKFTRFDANSSQPSIIKSSSSIYVDKNRIDVDQCGSDNLASQKFDLHFFKKIPLGAETSNIMVGETDFLNQMVVVFIRLKEAVILGELTEVPVPTRFVFVMLGPQGSAVKNHEIGRSMATLMSDDVFHDVAYKARNLDDLLAGIDEFLSNCTVLPPAEWDPSIRIEPPKSGPIARKVPSMPNGAQALLTASGDGRGGNNNGTPSSGTGPASVVNKLQPVEEESHADPTLRRTGRLFGGLIEDVKRKAPFYLSDFKDAIHVQCFASFFFLYFACLTPIITFGGLLVQATGGYLGAIESILSGTIVGVVYSLFSGQPLTIMGSTGPVLVFESIVYNICERMRWDYLPFRLWIGVWIAAYLFLMVAFDLSALVRYITRFTEESFAALIALIFMVEAFKKLFLIVDYYPIDTRWNIDMIKNRTCECFPRNATAMDAFFQKNNKPSNVYMPPMLYPVPLNSSVIDIVNNIDWQNISNYHFTWDYKKYRLICTKWGGIWTG GCGNYFIPDVFFFSCLLFIGTFVLSYGLKMMRNAQFFPNWVRSLISDFAVMIAISSMTLLDWSLGFHTPKLNVPAKFEPTLGY+MRGWVIPALGKNPWWTIIIAMGPALLAVILIFMDQQITAVIVNRKENKLKKGSGYHLDLLVVAILILVNSILGIPWFVAATVLSINHVMSLKKESENTAPGERPVFLGCREQRVTGTIIFLVIGLSVFLTPLLKRIPMAVLYGVFLFMGVASLKGVQLMQRISLFFMPAKYQPDYIFLRYVPLRRVHLFTIIQIILLVLLWVIKTINVMSICFPIMVLALCFVRKGLEYLFTYNELKWLDDIMPNHKKPPQDDNENDIEKCGSTELIKMTETNLEFNSSTNKVIRSNDSGINISEEMGKTAIWKQLSGGTKSGHSKNKKRKKREHNAADRSGNKDMESGDQGNSDNSHVQPLLNDSRESGRDNKHHYMTTPEIVVNPPSARESPELKHQNPKV
Sbjct:    1 MDITVGDEPILDRGFQFTHYHPSEDEIEDHRSQRALYIGVHMPPDRIHQPTRQRRRRHKKSKQGQHDKKDYLTEIAEDDTEKATDPSQHVMFLLGEDEDEETHNLFCEMDELRLDDEGEPEWKETARWIKFEEDVEEGGERWSKPHVASLSLYSLFEVRNCITSAVNMFNVEANNFETIIEIILNKIVSEKKISPDQREKVKEMLQRKHVHLHERRHKSNAKGSQLPLIRSLADIGKKYSSKEVDKVQLQRRNSDYPTKFTRFDANSSQPSIIKSSSSIYVDKNRIDVDQCGSDNLASQKFDLHFFKKIPLGAETSNIMVGETDFLNQMVVVFIRLKEAVILGELTEVPVPTRFVFVMLGPQGSAVKNHEIGRSMATLMSDDVFHDVAYKARNLDDLLAGIDEFLSNCTVLPPAEWDPSIRIEPPKSGPIARKVPSMPNGAQALLTASGDGRGGNNNGTPSSGTGPASVVNKLQPVEEESHADPTLRRTGRLFGGLIEDVKRKAPFYLSDFKDAIHVQCFASFFFLYFACLTPIITFGGLLVQATGGYLGAIESILSGTIVGVVYSLFSGQPLTIMGSTGPVLVFESIVYNICERMRWDYLPFRLWIGVWIAAYLFLMVAFDLSALVRYITRFTEESFAALIALIFMVEAFKKLFLIVDYYPIDTRWNIDMIKNRTCECFPRNATAMDAFFQKNNKPSNVYMPPMLYPVPLNSSVIDIVNNIDWQNISNYHFTWDYKKYRLICTKWGGIWTGPGCGNYFIPDVFFFSCLLFIGTFVLSYGLKMMRNAQFFPNWVRSLISDFAVMIAISSMTLLDWSLGFHTPKLNVPAKFEPTLGYEMRGWVIPALGKNPWWTIIIAMGPALLAVILIFMDQQITAVIVNRKENKLKKGSGYHLDLLVVAILILVNSILGIPWFVAATVLSINHVMSLKKESENTAPGERPVFLGCREQRVTGTIIFLVIGLSVFLTPLLKRIPMAVLYGVFLFMGVASLKGVQLMQRISLFFMPAKYQPDYIFLRYVPLRRVHLFTIIQIILLVLLWVIKTINVMSICFPIMVLALCFVRKGLEYLFTYNELKWLDDIMPNHKKPPQDDNENDIEKCGSTELIKMTETNLEFNSSTNKVIRSNDSGINISEEMGKTAIWKQLSGGTKSGHSKNKKRKKREHNAADRSGNKDMESGDQGNSDNSHVQPLLNDSRESGRDNKHHYMTTPEIVVNPPSARESPELKHQNPKV 1230          
BLAST of slc4a-1 vs. Planmine SMEST
Match: SMESG000024335.1 (SMESG000024335.1)

HSP 1 Score: 2276.52 bits (5898), Expect = 0.000e+0
Identity = 1220/1230 (99.19%), Postives = 1223/1230 (99.43%), Query Frame = 2
Query:  107 MDITVGDEPILDRGFQFTHYHPSEDEIEDHRSQRALYIGVHMPPDXXXXXXXXXXXXXXXXXXXXXDKKDYLTEIAEDDTEKATDPSQHVMFLLGEDEDEETHNLFCEMDELRLDDEGEPEWKETARWIKFEEDVEEGGERWSKPHVASLSLYSLFEVRNCITSAVNMFNVEANNFETIIEIILNKIVSEKKISPDQREKVKEMLQRKHVHLHERRHKSNAKGSQLPLIRSLADIGKKYSSKEVDKVQLQRRNSDYPTKFTRFDANXXXXXXXXXXXXXYVDKNRIDVDQCGSDNLASQKFDLHFFKKIPLGAETSNIMVGETDFLNQMVVVFIRLKEAVILGELTEVPVPTRFVFVMLGPQGSAVKNHEIGRSMATLMSDDVFHDVAYKARNLDDLLAGIDEFLSNCTVLPPAEWDPSIRIEPPKSGPIARKVPSMPNGAQALLTASGDGRXXXXXXXXXXXXXXASVVNKLQPVEEESHADPTLRRTGRLFGGLIEDVKRKAPFYLSDFKDAIHVQCFASFFFLYFACLTPIITFGGLLVQATGGYLGAIESILSGTIVGVVYSLFSGQPLTIMGSTGPVLVFESIVYNICERMRWDYLPFRLWIGVWIAAYLFLMVAFDLSALVRYITRFTEESFAALIALIFMVEAFKKLFLIVDYYPIDTRWNIDMIKNRTCECFPRNATAMDAFFQKNNKPSNVYMPPMLYPVPLNSSVIDIVNNIDWQNISNYHFTWDYKKYRLICTKWGGIWTGSGCGNYFIPDVFFFSCLLFIGTFVLSYGLKMMRNAQFFPNWVRSLISDFAVMIAISSMTLLDWSLGFHTPKLNVPAKFEPTLGYKMRGWVIPALGKNPWWTIIIAMGPALLAVILIFMDQQITAVIVNRKENKLKKGSGYHXXXXXXXXXXXXXXXXGIPWFVAATVLSINHVMSLKKESENTAPGERPVFLGCREQRVTGTIIFLVIGLSVFLTPLLKRIPMAVLYGVFLFMGVASLKGVQLMQRISLFFMPAKYQPDYIFLRYVPLRRVHXXXXXXXXXXXXXXXXXXXNVMSICFPIMVLALCFVRKGLEYLFTYNELKWLDDIMPNHKKPPQDDNENDIEKCGSTELIKMTETNLEFNSSTNKVIRSNDSGINISEEMGKTAIWKQLSGGTXXXXXXXXXXXXXXXXXXDRSGNKDMESGDQGNSDNSHVQPLLNDSRESGRDNKHHYMTTPEIVVNPPSARESPELKHQNPKV 3796
            MDITVGDEPILDRGFQFTHYHPSEDEIEDHRSQRALYIGVHMPPDRIHQPTRQRRRRHKKSKQGQHDKKDYLTEIAEDDTEKATDPSQHVMFLLGEDEDEETHNLFCEMDELRLDDEGEPEWKETARWIKFEEDVEEGGERWSKPHVASLSLYSLFEVRNCITSAVNMFNVEANNFETIIEIILNKIVSEKKISPDQREKVKEMLQRKHVHLHERRHKSNAKGSQLPLIRSLADIGKKYSSKEVDKVQLQRRNSD+  +    DANSSQPSIIKSSSSIYVDKNRIDVDQCGSDNLASQKFDLHFFKKIPLGAETSNIMVGETDFLNQMVVVFIRLKEAVILGELTEVPVPTRFVFVMLGPQGSAVKNHEIGRSMATLMSDDVFHDVAYKARNLDDLLAGIDEFLSNCTVLPPAEWDPSIRIEPPKSGPIARKVPSMPNGAQALLTASGDGRGGNNNGTPSSGTGPASVVNKLQPVEEESHADPTLRRTGRLFGGLIEDVKRKAPFYLSDFKDAIHVQCFASFFFLYFACLTPIITFGGLLVQATGGYLGAIESILSGTIVGVVYSLFSGQPLTIMGSTGPVLVFESIVYNICERMRWDYLPFRLWIGVWIAAYLFLMVAFDLSALVRYITRFTEESFAALIALIFMVEAFKKLFLIVDYYPIDTRWNIDMIKNRTCECFPRNATAMDAFFQKNNKPSNVYMPPMLYPVPLNSSVIDIVNNIDWQNISNYHFTWDYKKYRLICTKWGGIWTG GCGNYFIPDVFFFSCLLFIGTFVLSYGLKMMRNAQFFPNWVRSLISDFAVMIAISSMTLLDWSLGFHTPKLNVPAKFEPTLGY+MRGWVIPALGKNPWWTIIIAMGPALLAVILIFMDQQITAVIVNRKENKLKKGSGYHLDLLVVAILILVNSILGIPWFVAATVLSINHVMSLKKESENTAPGERPVFLGCREQRVTGTIIFLVIGLSVFLTPLLKRIPMAVLYGVFLFMGVASLKGVQLMQRISLFFMPAKYQPDYIFLRYVPLRRVHLFTIIQIILLVLLWVIKTINVMSICFPIMVLALCFVRKGLEYLFTYNELKWLDDIMPNHKKPPQDDNENDIEKCGSTELIKMTETNLEFNSSTNKVIRSNDSGINISEEMGKTAIWKQLSGGTKSGHSKNKKRKKREHNAADRSGNKDMESGDQGNSDNSHVQPLLNDSRESGRDNKHHYMTTPEIVVNPPSARESPELKHQNPKV
Sbjct:    1 MDITVGDEPILDRGFQFTHYHPSEDEIEDHRSQRALYIGVHMPPDRIHQPTRQRRRRHKKSKQGQHDKKDYLTEIAEDDTEKATDPSQHVMFLLGEDEDEETHNLFCEMDELRLDDEGEPEWKETARWIKFEEDVEEGGERWSKPHVASLSLYSLFEVRNCITSAVNMFNVEANNFETIIEIILNKIVSEKKISPDQREKVKEMLQRKHVHLHERRHKSNAKGSQLPLIRSLADIGKKYSSKEVDKVQLQRRNSDHEER----DANSSQPSIIKSSSSIYVDKNRIDVDQCGSDNLASQKFDLHFFKKIPLGAETSNIMVGETDFLNQMVVVFIRLKEAVILGELTEVPVPTRFVFVMLGPQGSAVKNHEIGRSMATLMSDDVFHDVAYKARNLDDLLAGIDEFLSNCTVLPPAEWDPSIRIEPPKSGPIARKVPSMPNGAQALLTASGDGRGGNNNGTPSSGTGPASVVNKLQPVEEESHADPTLRRTGRLFGGLIEDVKRKAPFYLSDFKDAIHVQCFASFFFLYFACLTPIITFGGLLVQATGGYLGAIESILSGTIVGVVYSLFSGQPLTIMGSTGPVLVFESIVYNICERMRWDYLPFRLWIGVWIAAYLFLMVAFDLSALVRYITRFTEESFAALIALIFMVEAFKKLFLIVDYYPIDTRWNIDMIKNRTCECFPRNATAMDAFFQKNNKPSNVYMPPMLYPVPLNSSVIDIVNNIDWQNISNYHFTWDYKKYRLICTKWGGIWTGPGCGNYFIPDVFFFSCLLFIGTFVLSYGLKMMRNAQFFPNWVRSLISDFAVMIAISSMTLLDWSLGFHTPKLNVPAKFEPTLGYEMRGWVIPALGKNPWWTIIIAMGPALLAVILIFMDQQITAVIVNRKENKLKKGSGYHLDLLVVAILILVNSILGIPWFVAATVLSINHVMSLKKESENTAPGERPVFLGCREQRVTGTIIFLVIGLSVFLTPLLKRIPMAVLYGVFLFMGVASLKGVQLMQRISLFFMPAKYQPDYIFLRYVPLRRVHLFTIIQIILLVLLWVIKTINVMSICFPIMVLALCFVRKGLEYLFTYNELKWLDDIMPNHKKPPQDDNENDIEKCGSTELIKMTETNLEFNSSTNKVIRSNDSGINISEEMGKTAIWKQLSGGTKSGHSKNKKRKKREHNAADRSGNKDMESGDQGNSDNSHVQPLLNDSRESGRDNKHHYMTTPEIVVNPPSARESPELKHQNPKV 1226          
BLAST of slc4a-1 vs. Planmine SMEST
Match: SMESG000024335.1 (SMESG000024335.1)

HSP 1 Score: 2276.13 bits (5897), Expect = 0.000e+0
Identity = 1221/1230 (99.27%), Postives = 1223/1230 (99.43%), Query Frame = 2
Query:  107 MDITVGDEPILDRGFQFTHYHPSEDEIEDHRSQRALYIGVHMPPDXXXXXXXXXXXXXXXXXXXXXDKKDYLTEIAEDDTEKATDPSQHVMFLLGEDEDEETHNLFCEMDELRLDDEGEPEWKETARWIKFEEDVEEGGERWSKPHVASLSLYSLFEVRNCITSAVNMFNVEANNFETIIEIILNKIVSEKKISPDQREKVKEMLQRKHVHLHERRHKSNAKGSQLPLIRSLADIGKKYSSKEVDKVQLQRRNSDYPTKFTRFDANXXXXXXXXXXXXXYVDKNRIDVDQCGSDNLASQKFDLHFFKKIPLGAETSNIMVGETDFLNQMVVVFIRLKEAVILGELTEVPVPTRFVFVMLGPQGSAVKNHEIGRSMATLMSDDVFHDVAYKARNLDDLLAGIDEFLSNCTVLPPAEWDPSIRIEPPKSGPIARKVPSMPNGAQALLTASGDGRXXXXXXXXXXXXXXASVVNKLQPVEEESHADPTLRRTGRLFGGLIEDVKRKAPFYLSDFKDAIHVQCFASFFFLYFACLTPIITFGGLLVQATGGYLGAIESILSGTIVGVVYSLFSGQPLTIMGSTGPVLVFESIVYNICERMRWDYLPFRLWIGVWIAAYLFLMVAFDLSALVRYITRFTEESFAALIALIFMVEAFKKLFLIVDYYPIDTRWNIDMIKNRTCECFPRNATAMDAFFQKNNKPSNVYMPPMLYPVPLNSSVIDIVNNIDWQNISNYHFTWDYKKYRLICTKWGGIWTGSGCGNYFIPDVFFFSCLLFIGTFVLSYGLKMMRNAQFFPNWVRSLISDFAVMIAISSMTLLDWSLGFHTPKLNVPAKFEPTLGYKMRGWVIPALGKNPWWTIIIAMGPALLAVILIFMDQQITAVIVNRKENKLKKGSGYHXXXXXXXXXXXXXXXXGIPWFVAATVLSINHVMSLKKESENTAPGERPVFLGCREQRVTGTIIFLVIGLSVFLTPLLKRIPMAVLYGVFLFMGVASLKGVQLMQRISLFFMPAKYQPDYIFLRYVPLRRVHXXXXXXXXXXXXXXXXXXXNVMSICFPIMVLALCFVRKGLEYLFTYNELKWLDDIMPNHKKPPQDDNENDIEKCGSTELIKMTETNLEFNSSTNKVIRSNDSGINISEEMGKTAIWKQLSGGTXXXXXXXXXXXXXXXXXXDRSGNKDMESGDQGNSDNSHVQPLLNDSRESGRDNKHHYMTTPEIVVNPPSARESPELKHQNPKV 3796
            MDITVGDEPILDRGFQFTHYHPSEDEIEDHRSQRALYIGVHMPPDRIHQPTRQRRRRHKKSKQGQHDKKDYLTEIAEDDTEKATDPSQHVMFLLGEDEDEETHNLFCEMDELRLDDEGEPEWKETARWIKFEEDVEEGGERWSKPHVASLSLYSLFEVRNCITSAVNMFNVEANNFETIIEIILNKIVSEKKISPDQREKVKEMLQRKHVHLHERRHKSNAKGSQLPLIRSLADIGKKYSSKEVDK   +R   DYPTKFTRFDANSSQPSIIKSSSSIYVDKNRIDVDQCGSDNLASQKFDLHFFKKIPLGAETSNIMVGETDFLNQMVVVFIRLKEAVILGELTEVPVPTRFVFVMLGPQGSAVKNHEIGRSMATLMSDDVFHDVAYKARNLDDLLAGIDEFLSNCTVLPPAEWDPSIRIEPPKSGPIARKVPSMPNGAQALLTASGDGRGGNNNGTPSSGTGPASVVNKLQPVEEESHADPTLRRTGRLFGGLIEDVKRKAPFYLSDFKDAIHVQCFASFFFLYFACLTPIITFGGLLVQATGGYLGAIESILSGTIVGVVYSLFSGQPLTIMGSTGPVLVFESIVYNICERMRWDYLPFRLWIGVWIAAYLFLMVAFDLSALVRYITRFTEESFAALIALIFMVEAFKKLFLIVDYYPIDTRWNIDMIKNRTCECFPRNATAMDAFFQKNNKPSNVYMPPMLYPVPLNSSVIDIVNNIDWQNISNYHFTWDYKKYRLICTKWGGIWTG GCGNYFIPDVFFFSCLLFIGTFVLSYGLKMMRNAQFFPNWVRSLISDFAVMIAISSMTLLDWSLGFHTPKLNVPAKFEPTLGY+MRGWVIPALGKNPWWTIIIAMGPALLAVILIFMDQQITAVIVNRKENKLKKGSGYHLDLLVVAILILVNSILGIPWFVAATVLSINHVMSLKKESENTAPGERPVFLGCREQRVTGTIIFLVIGLSVFLTPLLKRIPMAVLYGVFLFMGVASLKGVQLMQRISLFFMPAKYQPDYIFLRYVPLRRVHLFTIIQIILLVLLWVIKTINVMSICFPIMVLALCFVRKGLEYLFTYNELKWLDDIMPNHKKPPQDDNENDIEKCGSTELIKMTETNLEFNSSTNKVIRSNDSGINISEEMGKTAIWKQLSGGTKSGHSKNKKRKKREHNAADRSGNKDMESGDQGNSDNSHVQPLLNDSRESGRDNKHHYMTTPEIVVNPPSARESPELKHQNPKV
Sbjct:    1 MDITVGDEPILDRGFQFTHYHPSEDEIEDHRSQRALYIGVHMPPDRIHQPTRQRRRRHKKSKQGQHDKKDYLTEIAEDDTEKATDPSQHVMFLLGEDEDEETHNLFCEMDELRLDDEGEPEWKETARWIKFEEDVEEGGERWSKPHVASLSLYSLFEVRNCITSAVNMFNVEANNFETIIEIILNKIVSEKKISPDQREKVKEMLQRKHVHLHERRHKSNAKGSQLPLIRSLADIGKKYSSKEVDKDHEER---DYPTKFTRFDANSSQPSIIKSSSSIYVDKNRIDVDQCGSDNLASQKFDLHFFKKIPLGAETSNIMVGETDFLNQMVVVFIRLKEAVILGELTEVPVPTRFVFVMLGPQGSAVKNHEIGRSMATLMSDDVFHDVAYKARNLDDLLAGIDEFLSNCTVLPPAEWDPSIRIEPPKSGPIARKVPSMPNGAQALLTASGDGRGGNNNGTPSSGTGPASVVNKLQPVEEESHADPTLRRTGRLFGGLIEDVKRKAPFYLSDFKDAIHVQCFASFFFLYFACLTPIITFGGLLVQATGGYLGAIESILSGTIVGVVYSLFSGQPLTIMGSTGPVLVFESIVYNICERMRWDYLPFRLWIGVWIAAYLFLMVAFDLSALVRYITRFTEESFAALIALIFMVEAFKKLFLIVDYYPIDTRWNIDMIKNRTCECFPRNATAMDAFFQKNNKPSNVYMPPMLYPVPLNSSVIDIVNNIDWQNISNYHFTWDYKKYRLICTKWGGIWTGPGCGNYFIPDVFFFSCLLFIGTFVLSYGLKMMRNAQFFPNWVRSLISDFAVMIAISSMTLLDWSLGFHTPKLNVPAKFEPTLGYEMRGWVIPALGKNPWWTIIIAMGPALLAVILIFMDQQITAVIVNRKENKLKKGSGYHLDLLVVAILILVNSILGIPWFVAATVLSINHVMSLKKESENTAPGERPVFLGCREQRVTGTIIFLVIGLSVFLTPLLKRIPMAVLYGVFLFMGVASLKGVQLMQRISLFFMPAKYQPDYIFLRYVPLRRVHLFTIIQIILLVLLWVIKTINVMSICFPIMVLALCFVRKGLEYLFTYNELKWLDDIMPNHKKPPQDDNENDIEKCGSTELIKMTETNLEFNSSTNKVIRSNDSGINISEEMGKTAIWKQLSGGTKSGHSKNKKRKKREHNAADRSGNKDMESGDQGNSDNSHVQPLLNDSRESGRDNKHHYMTTPEIVVNPPSARESPELKHQNPKV 1227          
BLAST of slc4a-1 vs. Planmine SMEST
Match: SMESG000024335.1 (SMESG000024335.1)

HSP 1 Score: 2267.27 bits (5874), Expect = 0.000e+0
Identity = 1221/1241 (98.39%), Postives = 1222/1241 (98.47%), Query Frame = 2
Query:  107 MDITVGDEPILDRGFQFTHYHPSEDEIEDHRSQRALYIGVHMPPDXXXXXXXXXXXXXXXXXXXXXDKKDYLTEIAEDDTEKATDPSQHVMFLLGEDEDEETHNLFCEMDELRLDDEGEPEWKETARWIKFEEDVEEGGERWSKPHVASLSLYSLFEVRNCITSAVNMFNVEANNFETIIEIILNKIVSEKKISPDQREKVKEMLQRKHVHLHERRHKSNAKGSQLPLIRSLADIGKKYSSKEVDKVQLQRRNSD--YPTKFTRF---------DANXXXXXXXXXXXXXYVDKNRIDVDQCGSDNLASQKFDLHFFKKIPLGAETSNIMVGETDFLNQMVVVFIRLKEAVILGELTEVPVPTRFVFVMLGPQGSAVKNHEIGRSMATLMSDDVFHDVAYKARNLDDLLAGIDEFLSNCTVLPPAEWDPSIRIEPPKSGPIARKVPSMPNGAQALLTASGDGRXXXXXXXXXXXXXXASVVNKLQPVEEESHADPTLRRTGRLFGGLIEDVKRKAPFYLSDFKDAIHVQCFASFFFLYFACLTPIITFGGLLVQATGGYLGAIESILSGTIVGVVYSLFSGQPLTIMGSTGPVLVFESIVYNICERMRWDYLPFRLWIGVWIAAYLFLMVAFDLSALVRYITRFTEESFAALIALIFMVEAFKKLFLIVDYYPIDTRWNIDMIKNRTCECFPRNATAMDAFFQKNNKPSNVYMPPMLYPVPLNSSVIDIVNNIDWQNISNYHFTWDYKKYRLICTKWGGIWTGSGCGNYFIPDVFFFSCLLFIGTFVLSYGLKMMRNAQFFPNWVRSLISDFAVMIAISSMTLLDWSLGFHTPKLNVPAKFEPTLGYKMRGWVIPALGKNPWWTIIIAMGPALLAVILIFMDQQITAVIVNRKENKLKKGSGYHXXXXXXXXXXXXXXXXGIPWFVAATVLSINHVMSLKKESENTAPGERPVFLGCREQRVTGTIIFLVIGLSVFLTPLLKRIPMAVLYGVFLFMGVASLKGVQLMQRISLFFMPAKYQPDYIFLRYVPLRRVHXXXXXXXXXXXXXXXXXXXNVMSICFPIMVLALCFVRKGLEYLFTYNELKWLDDIMPNHKKPPQDDNENDIEKCGSTELIKMTETNLEFNSSTNKVIRSNDSGINISEEMGKTAIWKQLSGGTXXXXXXXXXXXXXXXXXXDRSGNKDMESGDQGNSDNSHVQPLLNDSRESGRDNKHHYMTTPEIVVNPPSARESPELKHQNPKV 3796
            MDITVGDEPILDRGFQFTHYHPSEDEIEDHRSQRALYIGVHMPPDRIHQPTRQRRRRHKKSKQGQHDKKDYLTEIAEDDTEKATDPSQHVMFLLGEDEDEETHNLFCEMDELRLDDEGEPEWKETARWIKFEEDVEEGGERWSKPHVASLSLYSLFEVRNCITSAVNMFNVEANNFETIIEIILNKIVSEKKISPDQREKVKEMLQRKHVHLHERRHKSNAKGSQLPLIRSLADIGKKYSSKEVDKVQLQRRNS   Y     R          DANSSQPSIIKSSSSIYVDKNRIDVDQCGSDNLASQKFDLHFFKKIPLGAETSNIMVGETDFLNQMVVVFIRLKEAVILGELTEVPVPTRFVFVMLGPQGSAVKNHEIGRSMATLMSDDVFHDVAYKARNLDDLLAGIDEFLSNCTVLPPAEWDPSIRIEPPKSGPIARKVPSMPNGAQALLTASGDGRGGNNNGTPSSGTGPASVVNKLQPVEEESHADPTLRRTGRLFGGLIEDVKRKAPFYLSDFKDAIHVQCFASFFFLYFACLTPIITFGGLLVQATGGYLGAIESILSGTIVGVVYSLFSGQPLTIMGSTGPVLVFESIVYNICERMRWDYLPFRLWIGVWIAAYLFLMVAFDLSALVRYITRFTEESFAALIALIFMVEAFKKLFLIVDYYPIDTRWNIDMIKNRTCECFPRNATAMDAFFQKNNKPSNVYMPPMLYPVPLNSSVIDIVNNIDWQNISNYHFTWDYKKYRLICTKWGGIWTG GCGNYFIPDVFFFSCLLFIGTFVLSYGLKMMRNAQFFPNWVRSLISDFAVMIAISSMTLLDWSLGFHTPKLNVPAKFEPTLGY+MRGWVIPALGKNPWWTIIIAMGPALLAVILIFMDQQITAVIVNRKENKLKKGSGYHLDLLVVAILILVNSILGIPWFVAATVLSINHVMSLKKESENTAPGERPVFLGCREQRVTGTIIFLVIGLSVFLTPLLKRIPMAVLYGVFLFMGVASLKGVQLMQRISLFFMPAKYQPDYIFLRYVPLRRVHLFTIIQIILLVLLWVIKTINVMSICFPIMVLALCFVRKGLEYLFTYNELKWLDDIMPNHKKPPQDDNENDIEKCGSTELIKMTETNLEFNSSTNKVIRSNDSGINISEEMGKTAIWKQLSGGTKSGHSKNKKRKKREHNAADRSGNKDMESGDQGNSDNSHVQPLLNDSRESGRDNKHHYMTTPEIVVNPPSARESPELKHQNPKV
Sbjct:    1 MDITVGDEPILDRGFQFTHYHPSEDEIEDHRSQRALYIGVHMPPDRIHQPTRQRRRRHKKSKQGQHDKKDYLTEIAEDDTEKATDPSQHVMFLLGEDEDEETHNLFCEMDELRLDDEGEPEWKETARWIKFEEDVEEGGERWSKPHVASLSLYSLFEVRNCITSAVNMFNVEANNFETIIEIILNKIVSEKKISPDQREKVKEMLQRKHVHLHERRHKSNAKGSQLPLIRSLADIGKKYSSKEVDKVQLQRRNSGKVYVAIAYRMCVCVYHEERDANSSQPSIIKSSSSIYVDKNRIDVDQCGSDNLASQKFDLHFFKKIPLGAETSNIMVGETDFLNQMVVVFIRLKEAVILGELTEVPVPTRFVFVMLGPQGSAVKNHEIGRSMATLMSDDVFHDVAYKARNLDDLLAGIDEFLSNCTVLPPAEWDPSIRIEPPKSGPIARKVPSMPNGAQALLTASGDGRGGNNNGTPSSGTGPASVVNKLQPVEEESHADPTLRRTGRLFGGLIEDVKRKAPFYLSDFKDAIHVQCFASFFFLYFACLTPIITFGGLLVQATGGYLGAIESILSGTIVGVVYSLFSGQPLTIMGSTGPVLVFESIVYNICERMRWDYLPFRLWIGVWIAAYLFLMVAFDLSALVRYITRFTEESFAALIALIFMVEAFKKLFLIVDYYPIDTRWNIDMIKNRTCECFPRNATAMDAFFQKNNKPSNVYMPPMLYPVPLNSSVIDIVNNIDWQNISNYHFTWDYKKYRLICTKWGGIWTGPGCGNYFIPDVFFFSCLLFIGTFVLSYGLKMMRNAQFFPNWVRSLISDFAVMIAISSMTLLDWSLGFHTPKLNVPAKFEPTLGYEMRGWVIPALGKNPWWTIIIAMGPALLAVILIFMDQQITAVIVNRKENKLKKGSGYHLDLLVVAILILVNSILGIPWFVAATVLSINHVMSLKKESENTAPGERPVFLGCREQRVTGTIIFLVIGLSVFLTPLLKRIPMAVLYGVFLFMGVASLKGVQLMQRISLFFMPAKYQPDYIFLRYVPLRRVHLFTIIQIILLVLLWVIKTINVMSICFPIMVLALCFVRKGLEYLFTYNELKWLDDIMPNHKKPPQDDNENDIEKCGSTELIKMTETNLEFNSSTNKVIRSNDSGINISEEMGKTAIWKQLSGGTKSGHSKNKKRKKREHNAADRSGNKDMESGDQGNSDNSHVQPLLNDSRESGRDNKHHYMTTPEIVVNPPSARESPELKHQNPKV 1241          
BLAST of slc4a-1 vs. Planmine SMEST
Match: SMESG000057490.1 (SMESG000057490.1)

HSP 1 Score: 905.59 bits (2339), Expect = 0.000e+0
Identity = 481/995 (48.34%), Postives = 653/995 (65.63%), Query Frame = 2
Query:  377 MFLLGEDEDEETHN---LFCEMDELRLDDEGEPEWKETARWIKFEEDVEEGGERWSKPHVASLSLYSLFEVRNCITSAVNMFNVEANNFETIIEIILNKIVSEKKISPDQREKVKEMLQRKHVHLHERRHKSNAKGSQLPLIRSLADIGKKYSSKEVDKVQLQRRNSDYPTKFTRFDANXXXXXXXXXXXXXYVDKNRIDVDQCGSDNLASQKFDLHFFKKIPLGAETSNIMVGETDFLNQMVVVFIRLKEAVILGELTEVPVPTRFVFVMLGPQGSAVKNHEIGRSMATLMSDDVFHDVAYKARNLDDLLAGIDEFLSNCTVLPPAEWDPSIRIEPPKSGPIARKVPSMPNGAQALLTASGDGRXXXXXXXXXXXXXXASVVNKLQPVEEESHADPTLRRTGRLFGGLIEDVKRKAPFYLSDFKDAIHVQCFASFFFLYFACLTPIITFGGLLVQATGGYLGAIESILSGTIVGVVYSLFSGQPLTIMGSTGPVLVFESIVYNICERMRWDYLPFRLWIGVWIAAYLFLMVAFDLSALVRYITRFTEESFAALIALIFMVEAFKKLFLIVDYYPIDTRWNIDMIKNRTCECFPRNATAMDAFFQKNNKPSNVYMPPMLYPVPLNSSVIDIVNNIDWQNISNYHFTWDYKKYRLICTKWGGIWTGSGCGNYFIPDVFFFSCLLFIGTFVLSYGLKMMRNAQFFPNWVRSLISDFAVMIAISSMTLLDWSLGFHTPKLNVPAKFEPTLGYKMRGWVIPALGKNPWWTIIIAMGPALLAVILIFMDQQITAVIVNRKENKLKKGSGYHXXXXXXXXXXXXXXXXGIPWFVAATVLSINHVMSLKKESENTAPGERPVFLGCREQRVTGTIIFLVIGLSVFLTPLLKRIPMAVLYGVFLFMGVASLKGVQLMQRISLFFMPAKYQPDYIFLRYVPLRRVHXXXXXXXXXXXXXXXXXXXNVMSICFPIMVLALCFVRKGLEYLFTYNELKWLDDIMPN 3352
            MF L   E+ +  N   LFC+++EL   +    +W E +RW+KFEE VE   E WSKPHV  LSL S+   ++ I  AV   N E  N E +I++IL K + EKK+   Q E++K++L   H++ H   H     GSQL L RS+ D   K   +   +  L    ++                                      D L   KF   F KKIPLG+E +NI+V E  FL++ + +FIRLK++ I+G  TEV +PTRF+ ++LG +G+    HE GR   +L+ D VF   AYKA    DL+  IDEFL +  V+PP EW+P+I+I+PPK     R V    N     L    D                 S+  K +P +EE   +  L+ TGR FGG ++DVKRK  FYLSDF+D++++QC ASF FLYFACL P ITFGGLLV+AT GYLGA+ESIL+  IVGV+YSLFSGQPLTI+G+TGP+LVFES+V+ IC   +WD+LPFR+WIG WI  +L ++VA DLS LV+Y+T FTEE FA LI+LI++V+AF+ LF +++ YPI+  WN + I NR+C C P N T +     ++ +    +  P + P   NS+   ++  IDW NI++ +F+W+   ++ +C  +GG W G+ CG  ++PD+FFFS +L IGTF ++YGLK+ RN+   P  VR  I  FAV+IAI   TL+D+ +G +TPKL VP+KFEPTLGY  R W++P LGKNPWW+ ++A  PA+LAVILIFMDQQIT +IVNRK NKLKKG GYHLD+ ++AILI VNS++G+PWFV +TVL++NHVMSLK ES N  PG  PVFLGCREQR+T  +I L IG SVF TP+L+RIPM VL+GVF +MGV+ L  + ++QRI LFF+ AK +PD+ +L+Y+P++RVHLFT IQ++ L+LL+ IK+IN++S+ FPI+VLA+CFVRK LE  F+  ELKWLD I+P 
Sbjct:    1 MFNLSSTENNDKDNQRYLFCQLNEL---EPSSNKWYECSRWVKFEEVVENTKEHWSKPHVGVLSLRSILTFKSMILHAVISLNHEGENIEDVIDLILRKAIDEKKLDFSQEEELKQLLSMCHLNPH---HNKCGIGSQLSLFRSIVDNPNKKMKQNPSRKTLCENGNE-------------------------------------EDGLLEYKFCSRFKKKIPLGSEVANILVAEIGFLSENLCLFIRLKQSSIIGAYTEVHLPTRFIIIILGTKGTLSNIHECGRVAGSLLVDSVFRKSAYKANETKDLIQAIDEFLDSALVIPPDEWNPNIKIDPPKEMIPDRLV----NNKDEPLHHEDD-----------------SISEKYKPTQEELEME--LKITGRFFGGFVDDVKRKKKFYLSDFRDSLNLQCLASFIFLYFACLAPTITFGGLLVKATDGYLGAMESILAAAIVGVLYSLFSGQPLTILGTTGPLLVFESVVFKICGYYKWDFLPFRMWIGFWIMIFLLIIVASDLSMLVKYLTTFTEECFAMLISLIYIVKAFQNLFELLEDYPINRNWNPNYILNRSCSCIPPNKTILSKSLDEHTQRLLKFEKPPMLPGFENSNFSQLL-YIDWNNITDGYFSWNTHNFKQMCVDYGGTWAGNTCGKLYVPDIFFFSSMLMIGTFTMAYGLKIFRNSDLLPCKVRETIGTFAVVIAIFMFTLIDFVIGMNTPKLIVPSKFEPTLGYSSRTWIVPILGKNPWWSTLLAFIPAILAVILIFMDQQITVIIVNRKSNKLKKGYGYHLDMFIIAILIGVNSLIGVPWFVGSTVLAMNHVMSLKIESSNNVPGVAPVFLGCREQRMTHLMISLAIGFSVFFTPMLQRIPMPVLFGVFFYMGVSPLSEIDMIQRIGLFFINAKKRPDFKYLQYIPIKRVHLFTAIQVLCLLLLFTIKSINILSVSFPILVLAMCFVRKSLECFFSQEELKWLDRILPQ 928          
The following BLAST results are available for this feature:
BLAST of slc4a-1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
SLC4A100.000e+047.31solute carrier family 4 member 10 [Source:HGNC Sym... [more]
SLC4A100.000e+047.31solute carrier family 4 member 10 [Source:HGNC Sym... [more]
SLC4A100.000e+047.31solute carrier family 4 member 10 [Source:HGNC Sym... [more]
SLC4A100.000e+046.86solute carrier family 4 member 10 [Source:HGNC Sym... [more]
SLC4A70.000e+046.92solute carrier family 4 member 7 [Source:HGNC Symb... [more]
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BLAST of slc4a-1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
abts-10.000e+046.46Anion exchange protein [Source:UniProtKB/TrEMBL;A... [more]
abts-10.000e+046.46Anion exchange protein [Source:UniProtKB/TrEMBL;A... [more]
abts-10.000e+044.27Anion exchange protein [Source:UniProtKB/TrEMBL;A... [more]
abts-32.613e-4429.47Anion/Bicarbonate TranSporter family [Source:UniP... [more]
abts-34.279e-4429.28Anion/Bicarbonate TranSporter family [Source:UniP... [more]
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BLAST of slc4a-1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Ndae10.000e+046.25gene:FBgn0259111 transcript:FBtr0331658[more]
Ndae10.000e+046.25gene:FBgn0259111 transcript:FBtr0299539[more]
Ndae10.000e+047.30gene:FBgn0259111 transcript:FBtr0331663[more]
Ndae10.000e+049.23gene:FBgn0259111 transcript:FBtr0331660[more]
Ndae10.000e+049.04gene:FBgn0259111 transcript:FBtr0331662[more]
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BLAST of slc4a-1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
slc4a80.000e+046.21solute carrier family 4 member 8 [Source:ZFIN;Acc:... [more]
slc4a10a0.000e+046.12solute carrier family 4 member 10a [Source:ZFIN;Ac... [more]
slc4a70.000e+047.01solute carrier family 4 member 7 [Source:ZFIN;Acc:... [more]
slc4a10a0.000e+046.12solute carrier family 4 member 10a [Source:ZFIN;Ac... [more]
slc4a10a0.000e+046.12solute carrier family 4 member 10a [Source:ZFIN;Ac... [more]
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BLAST of slc4a-1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
crhbp0.000e+047.31corticotropin releasing hormone binding protein [S... [more]
tbx50.000e+047.53T-box 5 [Source:Xenbase;Acc:XB-GENE-486855][more]
tbx50.000e+047.53T-box 5 [Source:Xenbase;Acc:XB-GENE-486855][more]
crhbp0.000e+047.60corticotropin releasing hormone binding protein [S... [more]
crhbp0.000e+047.98corticotropin releasing hormone binding protein [S... [more]
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BLAST of slc4a-1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Slc4a100.000e+047.07solute carrier family 4, sodium bicarbonate cotran... [more]
Slc4a100.000e+047.47solute carrier family 4, sodium bicarbonate cotran... [more]
Slc4a100.000e+047.30solute carrier family 4, sodium bicarbonate cotran... [more]
Slc4a70.000e+046.76solute carrier family 4, sodium bicarbonate cotran... [more]
Slc4a70.000e+046.76solute carrier family 4, sodium bicarbonate cotran... [more]
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BLAST of slc4a-1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q5DTL9|S4A10_MOUSE0.000e+047.07Sodium-driven chloride bicarbonate exchanger OS=Mu... [more]
sp|Q80ZA5|S4A10_RAT0.000e+047.20Sodium-driven chloride bicarbonate exchanger OS=Ra... [more]
sp|Q32LP4|S4A10_BOVIN0.000e+046.94Sodium-driven chloride bicarbonate exchanger OS=Bo... [more]
sp|Q6U841|S4A10_HUMAN0.000e+046.86Sodium-driven chloride bicarbonate exchanger OS=Ho... [more]
sp|Q8JZR6|S4A8_MOUSE0.000e+046.98Electroneutral sodium bicarbonate exchanger 1 OS=M... [more]
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BLAST of slc4a-1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A0H3YF380.000e+0100.00Anion exchange protein OS=Schmidtea mediterranea O... [more]
A0A4S2LRB50.000e+050.11Anion exchange protein OS=Opisthorchis felineus OX... [more]
G7YU350.000e+050.30Anion exchange protein OS=Clonorchis sinensis OX=7... [more]
A0A074YZZ70.000e+052.76Anion exchange protein OS=Opisthorchis viverrini O... [more]
A0A419PX980.000e+051.98Anion exchange protein (Fragment) OS=Clonorchis si... [more]
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BLAST of slc4a-1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
slc4a80.000e+046.89solute carrier family 4 member 8 [Source:ZFIN;Acc:... [more]
slc4a10b0.000e+046.42solute carrier family 4 member 10 [Source:NCBI gen... [more]
slc4a10a0.000e+046.45sodium-driven chloride bicarbonate exchanger-like ... [more]
slc4a10b0.000e+046.48solute carrier family 4 member 10 [Source:NCBI gen... [more]
slc4a10a0.000e+046.37sodium-driven chloride bicarbonate exchanger-like ... [more]
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BLAST of slc4a-1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
slc4a77.246e-4148.59solute carrier family 4 member 7 [Source:ZFIN;Acc:... [more]
slc4a71.159e-17947.85solute carrier family 4 member 7 [Source:ZFIN;Acc:... [more]
SLC4A21.930e-16735.04solute carrier family 4 member 2 [Source:HGNC Symb... [more]
SLC4A41.323e-13846.96solute carrier family 4 member 4 [Source:HGNC Symb... [more]
SLC4A46.783e-13647.11solute carrier family 4 member 4 [Source:HGNC Symb... [more]
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BLAST of slc4a-1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1
Match NameE-valueIdentityDescription
BOR16.754e-1930.36Boron efflux transporter of the plasma membrane; b... [more]
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BLAST of slc4a-1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO458448.903e-15934.11Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO317933.100e-9834.31Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO270891.264e-3857.02Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO406109.420e-2140.59Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO406119.683e-1425.62Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of slc4a-1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
slc4a80.000e+046.43electroneutral sodium bicarbonate exchanger 1 [Sou... [more]
slc4a10a0.000e+046.37sodium-driven chloride bicarbonate exchanger [Sour... [more]
slc4a10a0.000e+046.37sodium-driven chloride bicarbonate exchanger [Sour... [more]
slc4a10a0.000e+046.37sodium-driven chloride bicarbonate exchanger [Sour... [more]
slc4a10a0.000e+048.04sodium-driven chloride bicarbonate exchanger [Sour... [more]
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BLAST of slc4a-1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000024335.10.000e+099.84SMESG000024335.1[more]
SMESG000024335.10.000e+099.19SMESG000024335.1[more]
SMESG000024335.10.000e+099.27SMESG000024335.1[more]
SMESG000024335.10.000e+098.39SMESG000024335.1[more]
SMESG000057490.10.000e+048.34SMESG000057490.1[more]
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Cross References
External references for this transcript
DatabaseAccession
SmedGD GBrowseSMED30018542
GenBankAKN21407.1
Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30018542 ID=SMED30018542|Name=slc4a-1|organism=Schmidtea mediterranea sexual|type=transcript|length=3938bp
CATTTTTATTGGCGATTATTTGTAAGAAATTTGTAATTTTGAACTAATAA
TCGTTTATTCTTAAATTAACATTTTAAGTAATATTTATTACTAATTACGA
TAAATAATGGATATCACTGTTGGAGATGAACCAATTCTCGATCGTGGATT
TCAGTTTACTCATTATCATCCATCGGAAGATGAAATTGAAGATCATCGAT
CCCAGCGAGCTCTATATATTGGGGTTCACATGCCTCCTGATCGAATTCAT
CAACCGACTCGACAGCGACGTCGACGACACAAAAAATCGAAGCAAGGCCA
ACATGACAAAAAAGACTATCTAACAGAAATTGCGGAGGATGACACCGAAA
AGGCTACTGATCCTAGCCAACATGTCATGTTTCTTCTTGGTGAAGATGAG
GACGAAGAAACCCATAACCTATTTTGTGAAATGGATGAATTACGATTGGA
TGATGAAGGCGAACCAGAATGGAAAGAAACCGCGAGATGGATTAAATTTG
AAGAAGATGTAGAAGAAGGCGGTGAAAGGTGGTCAAAGCCTCACGTAGCC
AGCTTATCTCTATATTCGCTGTTTGAAGTCCGAAATTGTATTACTTCGGC
AGTTAACATGTTCAACGTTGAAGCAAATAATTTTGAAACCATTATTGAAA
TTATACTGAACAAAATTGTGTCCGAGAAGAAAATCTCACCAGATCAGCGG
GAAAAAGTCAAAGAAATGTTACAGAGAAAGCATGTGCATTTGCATGAACG
AAGACATAAAAGCAATGCTAAAGGTAGTCAGTTGCCTCTTATAAGATCAT
TGGCAGACATTGGTAAAAAGTATTCATCAAAAGAAGTGGATAAAGTCCAA
TTACAACGCCGCAATTCAGATTATCCAACAAAGTTTACTAGATTTGATGC
AAACAGTAGTCAACCTAGTATTATAAAATCGAGTAGCTCTATTTATGTCG
ATAAAAACAGAATAGACGTTGATCAGTGTGGTTCCGACAATCTGGCGTCA
CAAAAGTTCGACTTACATTTCTTTAAAAAGATACCACTGGGTGCTGAAAC
ATCAAATATTATGGTGGGGGAAACTGATTTTCTTAATCAGATGGTTGTTG
TGTTTATTCGGTTGAAAGAAGCTGTAATTCTAGGAGAATTGACTGAAGTC
CCTGTGCCGACACGATTTGTGTTTGTTATGTTAGGACCTCAAGGTAGCGC
AGTCAAAAATCACGAAATTGGGAGGTCAATGGCTACTCTAATGTCGGATG
ATGTTTTTCATGACGTGGCCTACAAAGCTCGTAATCTTGATGATCTGTTA
GCGGGTATCGATGAATTTTTATCCAATTGTACTGTTTTACCGCCTGCTGA
ATGGGATCCTTCTATCAGAATCGAACCGCCCAAGAGTGGTCCGATAGCAA
GAAAAGTACCGAGTATGCCTAATGGTGCTCAAGCATTATTGACAGCTAGT
GGTGATGGAAGAGGTGGAAATAACAATGGAACCCCCAGTAGTGGTACAGG
ACCAGCATCTGTAGTTAATAAATTACAACCTGTAGAAGAAGAGAGCCACG
CGGATCCTACCCTTCGAAGAACTGGGCGACTTTTTGGTGGTCTTATTGAG
GATGTCAAGAGAAAAGCTCCTTTCTATCTCAGTGATTTCAAAGATGCAAT
TCATGTTCAATGTTTCGCATCTTTTTTCTTTCTTTACTTTGCTTGTCTAA
CACCAATAATTACATTTGGTGGTCTACTCGTTCAAGCCACTGGTGGCTAT
TTAGGTGCAATAGAATCCATTTTATCTGGTACAATTGTTGGAGTCGTTTA
CTCATTATTTTCTGGTCAACCCCTTACAATTATGGGCAGCACTGGGCCTG
TTCTCGTATTTGAGTCGATTGTTTATAATATCTGCGAACGAATGCGATGG
GATTATTTACCTTTTCGACTTTGGATAGGAGTATGGATAGCAGCTTATCT
TTTTCTTATGGTGGCCTTTGATTTGAGTGCCCTTGTTCGATACATTACTC
GTTTTACAGAAGAGAGTTTTGCTGCACTTATTGCATTGATTTTTATGGTT
GAAGCTTTTAAAAAATTGTTCTTGATTGTTGATTATTATCCCATTGATAC
TCGTTGGAACATTGATATGATAAAAAATCGAACTTGTGAATGCTTTCCGA
GAAACGCGACGGCAATGGATGCTTTTTTTCAAAAGAACAATAAGCCAAGT
AACGTTTATATGCCGCCTATGCTATATCCAGTGCCATTGAATTCCAGTGT
TATCGATATTGTGAACAATATTGATTGGCAAAACATATCTAACTATCACT
TCACTTGGGATTATAAGAAATACAGACTGATTTGTACGAAATGGGGAGGC
ATATGGACTGGATCAGGATGCGGAAATTACTTCATTCCTGATGTGTTTTT
CTTCTCGTGCCTGTTATTTATTGGTACCTTCGTTCTATCATATGGACTGA
AAATGATGAGAAATGCTCAATTTTTCCCTAATTGGGTCCGTAGCCTGATA
TCAGATTTTGCTGTTATGATTGCAATTTCCTCAATGACTTTACTCGATTG
GTCGCTTGGTTTTCACACTCCCAAATTGAATGTACCCGCCAAATTCGAAC
CAACCCTTGGATACAAAATGCGTGGTTGGGTGATTCCTGCTTTAGGAAAG
AATCCTTGGTGGACAATTATAATAGCCATGGGTCCTGCTTTATTAGCTGT
CATTCTCATTTTCATGGACCAGCAAATTACTGCAGTTATTGTAAATAGAA
AAGAAAATAAACTGAAGAAAGGCAGTGGTTATCATCTTGATTTACTCGTG
GTAGCAATTTTAATCCTTGTGAATTCAATACTTGGTATTCCGTGGTTTGT
CGCCGCAACAGTCTTATCTATCAATCATGTTATGAGTTTGAAAAAAGAAT
CAGAAAATACCGCTCCAGGTGAGCGTCCAGTATTTCTTGGGTGCAGAGAG
CAGAGAGTAACTGGAACAATAATTTTCCTCGTTATTGGATTGTCAGTATT
TTTAACTCCTTTATTGAAAAGAATACCAATGGCAGTACTTTATGGTGTAT
TTCTATTCATGGGGGTCGCCTCATTGAAAGGAGTGCAGTTAATGCAGCGA
ATATCATTGTTTTTCATGCCTGCAAAATATCAACCCGATTACATATTCTT
AAGATATGTTCCCCTTCGAAGAGTTCATTTATTTACAATAATACAGATAA
TATTATTAGTCCTATTATGGGTTATTAAAACAATAAACGTTATGTCAATC
TGTTTCCCGATTATGGTTCTTGCGTTATGTTTTGTTCGCAAAGGCCTGGA
GTATTTGTTTACATACAATGAATTAAAATGGCTCGACGATATAATGCCAA
ATCATAAAAAACCTCCACAAGATGACAATGAGAACGATATAGAGAAATGC
GGCTCGACTGAACTAATCAAAATGACAGAAACAAATCTGGAATTTAATTC
CTCGACAAATAAAGTTATACGCAGCAATGATTCAGGAATCAACATCAGCG
AGGAAATGGGTAAAACTGCTATATGGAAGCAACTTTCTGGCGGTACAAAA
TCTGGCCATTCTAAAAATAAAAAGCGAAAGAAACGCGAGCACAATGCAGC
AGATCGGTCTGGTAATAAAGATATGGAATCCGGTGATCAAGGAAATTCAG
ATAATAGTCATGTTCAACCATTACTTAATGATTCTCGAGAATCGGGAAGA
GATAATAAGCATCATTATATGACCACCCCTGAGATTGTTGTCAATCCTCC
TTCTGCGAGAGAGTCTCCAGAATTAAAACATCAAAATCCGAAAGTTTAAT
CAACTCTTTATCTTAGCTTTAGATATGCTCTATGAACTTGTGCTCATTTG
TAGTTCTTAGTATAATTTCATGTGTATTCGTGTTTGTTCGGATCACAAAT
TTGTCATTTCTATTACTAACTTTCAAAGCAAAGCGATT
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protein sequence of SMED30018542-orf-1

>SMED30018542-orf-1 ID=SMED30018542-orf-1|Name=SMED30018542-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=1231bp
MDITVGDEPILDRGFQFTHYHPSEDEIEDHRSQRALYIGVHMPPDRIHQP
TRQRRRRHKKSKQGQHDKKDYLTEIAEDDTEKATDPSQHVMFLLGEDEDE
ETHNLFCEMDELRLDDEGEPEWKETARWIKFEEDVEEGGERWSKPHVASL
SLYSLFEVRNCITSAVNMFNVEANNFETIIEIILNKIVSEKKISPDQREK
VKEMLQRKHVHLHERRHKSNAKGSQLPLIRSLADIGKKYSSKEVDKVQLQ
RRNSDYPTKFTRFDANSSQPSIIKSSSSIYVDKNRIDVDQCGSDNLASQK
FDLHFFKKIPLGAETSNIMVGETDFLNQMVVVFIRLKEAVILGELTEVPV
PTRFVFVMLGPQGSAVKNHEIGRSMATLMSDDVFHDVAYKARNLDDLLAG
IDEFLSNCTVLPPAEWDPSIRIEPPKSGPIARKVPSMPNGAQALLTASGD
GRGGNNNGTPSSGTGPASVVNKLQPVEEESHADPTLRRTGRLFGGLIEDV
KRKAPFYLSDFKDAIHVQCFASFFFLYFACLTPIITFGGLLVQATGGYLG
AIESILSGTIVGVVYSLFSGQPLTIMGSTGPVLVFESIVYNICERMRWDY
LPFRLWIGVWIAAYLFLMVAFDLSALVRYITRFTEESFAALIALIFMVEA
FKKLFLIVDYYPIDTRWNIDMIKNRTCECFPRNATAMDAFFQKNNKPSNV
YMPPMLYPVPLNSSVIDIVNNIDWQNISNYHFTWDYKKYRLICTKWGGIW
TGSGCGNYFIPDVFFFSCLLFIGTFVLSYGLKMMRNAQFFPNWVRSLISD
FAVMIAISSMTLLDWSLGFHTPKLNVPAKFEPTLGYKMRGWVIPALGKNP
WWTIIIAMGPALLAVILIFMDQQITAVIVNRKENKLKKGSGYHLDLLVVA
ILILVNSILGIPWFVAATVLSINHVMSLKKESENTAPGERPVFLGCREQR
VTGTIIFLVIGLSVFLTPLLKRIPMAVLYGVFLFMGVASLKGVQLMQRIS
LFFMPAKYQPDYIFLRYVPLRRVHLFTIIQIILLVLLWVIKTINVMSICF
PIMVLALCFVRKGLEYLFTYNELKWLDDIMPNHKKPPQDDNENDIEKCGS
TELIKMTETNLEFNSSTNKVIRSNDSGINISEEMGKTAIWKQLSGGTKSG
HSKNKKRKKREHNAADRSGNKDMESGDQGNSDNSHVQPLLNDSRESGRDN
KHHYMTTPEIVVNPPSARESPELKHQNPKV*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000099neuron
PLANA:0000101muscle cell
PLANA:0000418head
PLANA:0000429neoblast
PLANA:0002109X1 cell
Vocabulary: INTERPRO
TermDefinition
IPR003020HCO3_transpt_euk
IPR003024Na/HCO3_transpt
IPR013769Band3_cytoplasmic_dom
IPR011531HCO3_transpt_C
IPR016152PTrfase/Anion_transptr
Vocabulary: molecular function
TermDefinition
GO:0005452inorganic anion exchanger activity
GO:0008509anion transmembrane transporter activity
GO:0005215transporter activity
Vocabulary: biological process
TermDefinition
GO:0006820anion transport
GO:0006810transport
GO:0006811ion transport
GO:0015698inorganic anion transport
GO:0098656anion transmembrane transport
Vocabulary: cellular component
TermDefinition
GO:0016020membrane
GO:0016021integral component of membrane
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR003024Sodium bicarbonate cotransporterPRINTSPR01232NAHCO3TRSPRTcoord: 359..367
score: 52.22
coord: 420..432
score: 65.38
coord: 410..418
score: 87.78
coord: 135..141
score: 81.43
coord: 400..408
score: 66.67
IPR003020Bicarbonate transporter, eukaryoticPRINTSPR01231HCO3TRNSPORTcoord: 509..518
score: 58.21
coord: 534..545
score: 69.05
coord: 349..361
score: 73.08
coord: 880..893
score: 65.31
coord: 624..636
score: 68.41
coord: 866..875
score: 84.64
IPR003020Bicarbonate transporter, eukaryoticTIGRFAMTIGR00834TIGR00834coord: 106..1094
e-value: 0.0
score: 1039.5
IPR003020Bicarbonate transporter, eukaryoticPANTHERPTHR11453ANION EXCHANGE PROTEINcoord: 54..1156
IPR016152Phosphotransferase/anion transporterGENE3DG3DSA:3.40.930.10coord: 99..433
e-value: 6.3E-103
score: 346.1
IPR016152Phosphotransferase/anion transporterSUPERFAMILYSSF55804Phoshotransferase/anion transport proteincoord: 105..429
NoneNo IPR availableGENE3DG3DSA:1.10.287.570coord: 502..543
e-value: 1.3E-20
score: 74.8
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 42..71
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 50..64
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 1141..1230
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 1174..1191
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 448..467
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 449..467
NoneNo IPR availablePANTHERPTHR11453:SF36SODIUM BICARBONATE COTRANSPORTER 3coord: 54..1156
NoneNo IPR availableTMHMMTMhelixcoord: 793..815
NoneNo IPR availableTMHMMTMhelixcoord: 1026..1060
NoneNo IPR availableTMHMMTMhelixcoord: 891..913
NoneNo IPR availableTMHMMTMhelixcoord: 851..870
NoneNo IPR availableTMHMMTMhelixcoord: 977..999
NoneNo IPR availableTMHMMTMhelixcoord: 547..569
NoneNo IPR availableTMHMMTMhelixcoord: 520..542
NoneNo IPR availableTMHMMTMhelixcoord: 605..627
NoneNo IPR availableTMHMMTMhelixcoord: 759..781
NoneNo IPR availableTMHMMTMhelixcoord: 951..970
NoneNo IPR availableTMHMMTMhelixcoord: 639..661
IPR011531Bicarbonate transporter, C-terminalPFAMPF00955HCO3_cotranspcoord: 486..1029
e-value: 2.3E-225
score: 749.2
IPR013769Band 3 cytoplasmic domainPFAMPF07565Band_3_cytocoord: 134..418
e-value: 2.6E-85
score: 286.5