Pre-mRNA-splicing factor 38A

Overview
NamePre-mRNA-splicing factor 38A
Smed IDSMED30018486
Length (bp)1057
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Pre-mRNA-splicing factor 38A (SMED30018486) t-SNE clustered cells

Violin plots show distribution of expression levels for Pre-mRNA-splicing factor 38A (SMED30018486) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Pre-mRNA-splicing factor 38A (SMED30018486) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Pre-mRNA-splicing factor 38A (SMED30018486) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30018486

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 8

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
X1 cellSMED30018486SMESG000012763.1 SmedASXL_008655SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
X2 cellSMED30018486SMESG000012763.1 SmedASXL_008655SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
neoblastSMED30018486SMESG000012763.1 dd_Smed_v4_3382_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30018486SMESG000012763.1 dd_Smed_v4_3382_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30018486SMESG000012763.1 Contig45676newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30018486SMESG000012763.1 Contig45676uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30018486SMESG000012763.1 Contig16340newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30018486SMESG000012763.1 Contig16340uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Pre-mRNA-splicing factor 38A vs. Ensembl Human
Match: PRPF38A (pre-mRNA processing factor 38A [Source:HGNC Symbol;Acc:HGNC:25930])

HSP 1 Score: 284.648 bits (727), Expect = 3.182e-94
Identity = 130/187 (69.52%), Postives = 157/187 (83.96%), Query Frame = 3 
Query:   33 MANRTVGDAHTIHGKNPQNLIEKVIRTRIYECRYWKEECFALTSELLVDKACELRYIGGVYGGNNIPTPFLCLLQKMLQIQPDKDIVIEFIKRNEFKYCRALGALYLRLTGDSTEIFKYLETLYNDYSKLKRQEESGKFVIVHMDEFIDELMRSDRVCSIILPRLQKRHVLESGNHLEPRISILDED 593
            MANRTV DAH+IHG NPQ L+EK+IRTRIYE +YWKEECF LT+EL+VDKA ELR++GGVYGGN  PTPFLCL  KMLQIQP+KDI++EFIK  +FKY R LGALY+RLTG + + +KYLE LYNDY K+K Q  +G+F ++H+DEFIDEL+ S+RVC IILPRLQKR+VLE    LEPR+S L+ED
Sbjct:    1 MANRTVKDAHSIHGTNPQYLVEKIIRTRIYESKYWKEECFGLTAELVVDKAMELRFVGGVYGGNIKPTPFLCLTLKMLQIQPEKDIIVEFIKNEDFKYVRMLGALYMRLTGTAIDCYKYLEPLYNDYRKIKSQNRNGEFELMHVDEFIDELLHSERVCDIILPRLQKRYVLEEAEQLEPRVSALEED 187
[Close]
BLAST of Pre-mRNA-splicing factor 38A vs. Ensembl Celegans
Match: prp-38 (Yeast PRP (Splicing factor) related [Source:UniProtKB/TrEMBL;Acc:Q18942])

HSP 1 Score: 251.136 bits (640), Expect = 1.861e-81
Identity = 120/187 (64.17%), Postives = 143/187 (76.47%), Query Frame = 3 
Query:   33 MANRTVGDAHTIHGKNPQNLIEKVIRTRIYECRYWKEECFALTSELLVDKACELRYIGGVYGGNNIPTPFLCLLQKMLQIQPDKDIVIEFIKRNEFKYCRALGALYLRLTGDSTEIFKYLETLYNDYSKLKRQEESGKFVIVHMDEFIDELMRSDRVCSIILPRLQKRHVLESGNHLEPRISILDED 593
            MANRT   A T+ G NPQ L+EK+IR RIY+  YWKE CFALT+EL+VDK  +LRYIGG+Y GN  PTPFLCL  KMLQIQPDKDIV+EFI++ EFKY RALGA+YLRLT DSTEI+KYLE LYND+ KL+   + G+F  ++MD+FID L+R DR C I LPRLQKR  LE  + L    S+LD D
Sbjct:    1 MANRTEKAAKTVKGTNPQFLVEKIIRQRIYDSMYWKEHCFALTAELVVDKGMDLRYIGGIYAGNIKPTPFLCLALKMLQIQPDKDIVLEFIQQEEFKYIRALGAMYLRLTFDSTEIYKYLEPLYNDFRKLRYMNKMGRFEAIYMDDFIDNLLREDRYCDIQLPRLQKRWALEEVDMLPSYKSLLDGD 187
[Close]
BLAST of Pre-mRNA-splicing factor 38A vs. Ensembl Fly
Match: Prp38 (gene:FBgn0050342 transcript:FBtr0088582)

HSP 1 Score: 278.87 bits (712), Expect = 4.993e-92
Identity = 128/187 (68.45%), Postives = 156/187 (83.42%), Query Frame = 3 
Query:   33 MANRTVGDAHTIHGKNPQNLIEKVIRTRIYECRYWKEECFALTSELLVDKACELRYIGGVYGGNNIPTPFLCLLQKMLQIQPDKDIVIEFIKRNEFKYCRALGALYLRLTGDSTEIFKYLETLYNDYSKLKRQEESGKFVIVHMDEFIDELMRSDRVCSIILPRLQKRHVLESGNHLEPRISILDED 593
            MANRTV +A  +HG NPQ LIEK+IR+RIY+ +YWKE+CFALT+ELLVDKA ELR++GGVYGGN  PT FLCL  KMLQIQP+KDIV+EFIK  EFKY RALGA YLRLTG + + +KYLE LY D  KL+RQ  +G+F IV+MDE+IDEL+R+DRVC IILPR+QKR +LE  N +EP++S+LDED
Sbjct:    1 MANRTVKEAKNVHGTNPQYLIEKIIRSRIYDSKYWKEQCFALTAELLVDKAMELRFVGGVYGGNIKPTQFLCLTLKMLQIQPEKDIVVEFIKNEEFKYVRALGAFYLRLTGAALDCYKYLEPLYIDNRKLRRQNRAGQFEIVYMDEYIDELLRNDRVCDIILPRIQKRSILEENNEIEPKVSVLDED 187
[Close]
BLAST of Pre-mRNA-splicing factor 38A vs. Ensembl Zebrafish
Match: prpf38a (pre-mRNA processing factor 38A [Source:NCBI gene;Acc:445089])

HSP 1 Score: 276.174 bits (705), Expect = 1.769e-91
Identity = 125/187 (66.84%), Postives = 156/187 (83.42%), Query Frame = 3 
Query:   33 MANRTVGDAHTIHGKNPQNLIEKVIRTRIYECRYWKEECFALTSELLVDKACELRYIGGVYGGNNIPTPFLCLLQKMLQIQPDKDIVIEFIKRNEFKYCRALGALYLRLTGDSTEIFKYLETLYNDYSKLKRQEESGKFVIVHMDEFIDELMRSDRVCSIILPRLQKRHVLESGNHLEPRISILDED 593
            MANRTV DA+++HG NPQ L+EK+IRTRIYE +YWKEECF LT+EL+VDKA EL+++GGVYGGN  PTPFLCL  KMLQIQP+KDI++EFIK  +FKY R LGA+Y+RLTG S + +KYLE LYNDY K+K Q  +G+F ++H+DEFIDEL+ ++R+C IILPRLQKR VLE    L+PRIS L+ED
Sbjct:    1 MANRTVKDANSVHGTNPQYLVEKIIRTRIYESKYWKEECFGLTAELVVDKAMELKFVGGVYGGNVKPTPFLCLTLKMLQIQPEKDIIVEFIKNEDFKYVRLLGAMYMRLTGTSVDCYKYLEPLYNDYRKIKSQNRNGEFELMHVDEFIDELLHAERMCDIILPRLQKRQVLEEAELLDPRISALEED 187
[Close]
BLAST of Pre-mRNA-splicing factor 38A vs. Ensembl Zebrafish
Match: prpf38a (pre-mRNA processing factor 38A [Source:NCBI gene;Acc:445089])

HSP 1 Score: 276.559 bits (706), Expect = 3.378e-91
Identity = 125/187 (66.84%), Postives = 156/187 (83.42%), Query Frame = 3 
Query:   33 MANRTVGDAHTIHGKNPQNLIEKVIRTRIYECRYWKEECFALTSELLVDKACELRYIGGVYGGNNIPTPFLCLLQKMLQIQPDKDIVIEFIKRNEFKYCRALGALYLRLTGDSTEIFKYLETLYNDYSKLKRQEESGKFVIVHMDEFIDELMRSDRVCSIILPRLQKRHVLESGNHLEPRISILDED 593
            MANRTV DA+++HG NPQ L+EK+IRTRIYE +YWKEECF LT+EL+VDKA EL+++GGVYGGN  PTPFLCL  KMLQIQP+KDI++EFIK  +FKY R LGA+Y+RLTG S + +KYLE LYNDY K+K Q  +G+F ++H+DEFIDEL+ ++R+C IILPRLQKR VLE    L+PRIS L+ED
Sbjct:    1 MANRTVKDANSVHGTNPQYLVEKIIRTRIYESKYWKEECFGLTAELVVDKAMELKFVGGVYGGNVKPTPFLCLTLKMLQIQPEKDIIVEFIKNEDFKYVRLLGAMYMRLTGTSVDCYKYLEPLYNDYRKIKSQNRNGEFELMHVDEFIDELLHAERMCDIILPRLQKRQVLEEAELLDPRISALEED 187
[Close]
BLAST of Pre-mRNA-splicing factor 38A vs. Ensembl Xenopus
Match: prpf38a (pre-mRNA processing factor 38A [Source:NCBI gene;Acc:549894])

HSP 1 Score: 279.641 bits (714), Expect = 2.737e-92
Identity = 126/187 (67.38%), Postives = 156/187 (83.42%), Query Frame = 3 
Query:   33 MANRTVGDAHTIHGKNPQNLIEKVIRTRIYECRYWKEECFALTSELLVDKACELRYIGGVYGGNNIPTPFLCLLQKMLQIQPDKDIVIEFIKRNEFKYCRALGALYLRLTGDSTEIFKYLETLYNDYSKLKRQEESGKFVIVHMDEFIDELMRSDRVCSIILPRLQKRHVLESGNHLEPRISILDED 593
            MANRTV DAH++HG NPQ L+EK+IRTRIYE +YWKEECF LT+EL+VDKA EL+Y+GGVYGGN  PTPFLCL  KMLQIQP+KDI++EFIK  +FKY R LGALY+RLTG +T+ +KYLE LYNDY K+K Q  +G+F ++H+DEFID+L+  +RVC +ILPRLQKR VLE    L+PR+S L+ED
Sbjct:    1 MANRTVKDAHSVHGTNPQYLVEKIIRTRIYESKYWKEECFGLTAELVVDKAMELKYVGGVYGGNIKPTPFLCLTLKMLQIQPEKDIIVEFIKNEDFKYVRTLGALYMRLTGTATDCYKYLEPLYNDYRKVKVQNRNGEFELMHVDEFIDQLLHEERVCDVILPRLQKRFVLEETEQLDPRVSALEED 187
[Close]
BLAST of Pre-mRNA-splicing factor 38A vs. Ensembl Mouse
Match: Prpf38a (PRP38 pre-mRNA processing factor 38 (yeast) domain containing A [Source:MGI Symbol;Acc:MGI:1916962])

HSP 1 Score: 282.722 bits (722), Expect = 1.091e-93
Identity = 129/187 (68.98%), Postives = 157/187 (83.96%), Query Frame = 3 
Query:   33 MANRTVGDAHTIHGKNPQNLIEKVIRTRIYECRYWKEECFALTSELLVDKACELRYIGGVYGGNNIPTPFLCLLQKMLQIQPDKDIVIEFIKRNEFKYCRALGALYLRLTGDSTEIFKYLETLYNDYSKLKRQEESGKFVIVHMDEFIDELMRSDRVCSIILPRLQKRHVLESGNHLEPRISILDED 593
            MANRTV DAH+IHG NPQ L+EK+IRTRIYE +YWKEECF LT+EL+VDKA EL+++GGVYGGN  PTPFLCL  KMLQIQP+KDI++EFIK  +FKY R LGALY+RLTG + + +KYLE LYNDY K+K Q  +G+FV++H+DEFI EL+ S+RVC IILPRLQKR+VLE    LEPR+S L+ED
Sbjct:    1 MANRTVKDAHSIHGTNPQYLVEKIIRTRIYESKYWKEECFGLTAELVVDKAMELKFVGGVYGGNIKPTPFLCLTLKMLQIQPEKDIIVEFIKNEDFKYVRMLGALYMRLTGTAIDCYKYLEPLYNDYRKIKSQNRNGEFVLMHVDEFIYELLHSERVCDIILPRLQKRYVLEEAEQLEPRVSALEED 187
[Close]
BLAST of Pre-mRNA-splicing factor 38A vs. UniProt/SwissProt
Match: sp|Q5RDD2|PR38A_PONAB (Pre-mRNA-splicing factor 38A OS=Pongo abelii OX=9601 GN=PRPF38A PE=2 SV=1)

HSP 1 Score: 284.648 bits (727), Expect = 1.528e-93
Identity = 130/187 (69.52%), Postives = 157/187 (83.96%), Query Frame = 3 
Query:   33 MANRTVGDAHTIHGKNPQNLIEKVIRTRIYECRYWKEECFALTSELLVDKACELRYIGGVYGGNNIPTPFLCLLQKMLQIQPDKDIVIEFIKRNEFKYCRALGALYLRLTGDSTEIFKYLETLYNDYSKLKRQEESGKFVIVHMDEFIDELMRSDRVCSIILPRLQKRHVLESGNHLEPRISILDED 593
            MANRTV DAH+IHG NPQ L+EK+IRTRIYE +YWKEECF LT+EL+VDKA ELR++GGVYGGN  PTPFLCL  KMLQIQP+KDI++EFIK  +FKY R LGALY+RLTG + + +KYLE LYNDY K+K Q  +G+F ++H+DEFIDEL+ S+RVC IILPRLQKR+VLE    LEPR+S L+ED
Sbjct:    1 MANRTVKDAHSIHGTNPQYLVEKIIRTRIYESKYWKEECFGLTAELVVDKAMELRFVGGVYGGNIKPTPFLCLTLKMLQIQPEKDIIVEFIKNEDFKYVRMLGALYMRLTGTAIDCYKYLEPLYNDYRKIKSQNRNGEFELMHVDEFIDELLHSERVCDIILPRLQKRYVLEEAEQLEPRVSALEED 187
[Close]
BLAST of Pre-mRNA-splicing factor 38A vs. UniProt/SwissProt
Match: sp|Q8HXH6|PR38A_MACFA (Pre-mRNA-splicing factor 38A OS=Macaca fascicularis OX=9541 GN=PRPF38A PE=2 SV=1)

HSP 1 Score: 284.648 bits (727), Expect = 1.528e-93
Identity = 130/187 (69.52%), Postives = 157/187 (83.96%), Query Frame = 3 
Query:   33 MANRTVGDAHTIHGKNPQNLIEKVIRTRIYECRYWKEECFALTSELLVDKACELRYIGGVYGGNNIPTPFLCLLQKMLQIQPDKDIVIEFIKRNEFKYCRALGALYLRLTGDSTEIFKYLETLYNDYSKLKRQEESGKFVIVHMDEFIDELMRSDRVCSIILPRLQKRHVLESGNHLEPRISILDED 593
            MANRTV DAH+IHG NPQ L+EK+IRTRIYE +YWKEECF LT+EL+VDKA ELR++GGVYGGN  PTPFLCL  KMLQIQP+KDI++EFIK  +FKY R LGALY+RLTG + + +KYLE LYNDY K+K Q  +G+F ++H+DEFIDEL+ S+RVC IILPRLQKR+VLE    LEPR+S L+ED
Sbjct:    1 MANRTVKDAHSIHGTNPQYLVEKIIRTRIYESKYWKEECFGLTAELVVDKAMELRFVGGVYGGNIKPTPFLCLTLKMLQIQPEKDIIVEFIKNEDFKYVRMLGALYMRLTGTAIDCYKYLEPLYNDYRKIKSQNRNGEFELMHVDEFIDELLHSERVCDIILPRLQKRYVLEEAEQLEPRVSALEED 187
[Close]
BLAST of Pre-mRNA-splicing factor 38A vs. UniProt/SwissProt
Match: sp|Q8NAV1|PR38A_HUMAN (Pre-mRNA-splicing factor 38A OS=Homo sapiens OX=9606 GN=PRPF38A PE=1 SV=1)

HSP 1 Score: 284.648 bits (727), Expect = 1.528e-93
Identity = 130/187 (69.52%), Postives = 157/187 (83.96%), Query Frame = 3 
Query:   33 MANRTVGDAHTIHGKNPQNLIEKVIRTRIYECRYWKEECFALTSELLVDKACELRYIGGVYGGNNIPTPFLCLLQKMLQIQPDKDIVIEFIKRNEFKYCRALGALYLRLTGDSTEIFKYLETLYNDYSKLKRQEESGKFVIVHMDEFIDELMRSDRVCSIILPRLQKRHVLESGNHLEPRISILDED 593
            MANRTV DAH+IHG NPQ L+EK+IRTRIYE +YWKEECF LT+EL+VDKA ELR++GGVYGGN  PTPFLCL  KMLQIQP+KDI++EFIK  +FKY R LGALY+RLTG + + +KYLE LYNDY K+K Q  +G+F ++H+DEFIDEL+ S+RVC IILPRLQKR+VLE    LEPR+S L+ED
Sbjct:    1 MANRTVKDAHSIHGTNPQYLVEKIIRTRIYESKYWKEECFGLTAELVVDKAMELRFVGGVYGGNIKPTPFLCLTLKMLQIQPEKDIIVEFIKNEDFKYVRMLGALYMRLTGTAIDCYKYLEPLYNDYRKIKSQNRNGEFELMHVDEFIDELLHSERVCDIILPRLQKRYVLEEAEQLEPRVSALEED 187
[Close]
BLAST of Pre-mRNA-splicing factor 38A vs. UniProt/SwissProt
Match: sp|Q0P5I6|PR38A_BOVIN (Pre-mRNA-splicing factor 38A OS=Bos taurus OX=9913 GN=PRPF38A PE=2 SV=1)

HSP 1 Score: 284.648 bits (727), Expect = 1.528e-93
Identity = 130/187 (69.52%), Postives = 157/187 (83.96%), Query Frame = 3 
Query:   33 MANRTVGDAHTIHGKNPQNLIEKVIRTRIYECRYWKEECFALTSELLVDKACELRYIGGVYGGNNIPTPFLCLLQKMLQIQPDKDIVIEFIKRNEFKYCRALGALYLRLTGDSTEIFKYLETLYNDYSKLKRQEESGKFVIVHMDEFIDELMRSDRVCSIILPRLQKRHVLESGNHLEPRISILDED 593
            MANRTV DAH+IHG NPQ L+EK+IRTRIYE +YWKEECF LT+EL+VDKA ELR++GGVYGGN  PTPFLCL  KMLQIQP+KDI++EFIK  +FKY R LGALY+RLTG + + +KYLE LYNDY K+K Q  +G+F ++H+DEFIDEL+ S+RVC IILPRLQKR+VLE    LEPR+S L+ED
Sbjct:    1 MANRTVKDAHSIHGTNPQYLVEKIIRTRIYESKYWKEECFGLTAELVVDKAMELRFVGGVYGGNIKPTPFLCLTLKMLQIQPEKDIIVEFIKNEDFKYVRMLGALYMRLTGTAIDCYKYLEPLYNDYRKIKSQNRNGEFELMHVDEFIDELLHSERVCDIILPRLQKRYVLEEAEQLEPRVSALEED 187
[Close]
BLAST of Pre-mRNA-splicing factor 38A vs. UniProt/SwissProt
Match: sp|Q4FK66|PR38A_MOUSE (Pre-mRNA-splicing factor 38A OS=Mus musculus OX=10090 GN=Prpf38a PE=1 SV=1)

HSP 1 Score: 282.722 bits (722), Expect = 7.632e-93
Identity = 129/187 (68.98%), Postives = 157/187 (83.96%), Query Frame = 3 
Query:   33 MANRTVGDAHTIHGKNPQNLIEKVIRTRIYECRYWKEECFALTSELLVDKACELRYIGGVYGGNNIPTPFLCLLQKMLQIQPDKDIVIEFIKRNEFKYCRALGALYLRLTGDSTEIFKYLETLYNDYSKLKRQEESGKFVIVHMDEFIDELMRSDRVCSIILPRLQKRHVLESGNHLEPRISILDED 593
            MANRTV DAH+IHG NPQ L+EK+IRTRIYE +YWKEECF LT+EL+VDKA EL+++GGVYGGN  PTPFLCL  KMLQIQP+KDI++EFIK  +FKY R LGALY+RLTG + + +KYLE LYNDY K+K Q  +G+FV++H+DEFI EL+ S+RVC IILPRLQKR+VLE    LEPR+S L+ED
Sbjct:    1 MANRTVKDAHSIHGTNPQYLVEKIIRTRIYESKYWKEECFGLTAELVVDKAMELKFVGGVYGGNIKPTPFLCLTLKMLQIQPEKDIIVEFIKNEDFKYVRMLGALYMRLTGTAIDCYKYLEPLYNDYRKIKSQNRNGEFVLMHVDEFIYELLHSERVCDIILPRLQKRYVLEEAEQLEPRVSALEED 187
[Close]
BLAST of Pre-mRNA-splicing factor 38A vs. TrEMBL
Match: W6UMV2 (Pre-mRNA-splicing factor 38A OS=Echinococcus granulosus OX=6210 GN=EGR_02341 PE=4 SV=1)

HSP 1 Score: 297.36 bits (760), Expect = 2.761e-96
Identity = 137/187 (73.26%), Postives = 159/187 (85.03%), Query Frame = 3 
Query:   33 MANRTVGDAHTIHGKNPQNLIEKVIRTRIYECRYWKEECFALTSELLVDKACELRYIGGVYGGNNIPTPFLCLLQKMLQIQPDKDIVIEFIKRNEFKYCRALGALYLRLTGDSTEIFKYLETLYNDYSKLKRQEESGKFVIVHMDEFIDELMRSDRVCSIILPRLQKRHVLESGNHLEPRISILDED 593
            MANRTV DAHT+HG NPQ L+EK+IR+RIYEC++WKE CFALTSELLVDKA EL+YIGG YGG   PTPF+CL+ KMLQIQPDKDIVIEFIK+ ++KY RALGA YLRL G+S EI+KYLE LYND+ KLK+Q+ +GKF IV MDEFID+L+  +RVC +ILPRLQKR VLE  N LEPR SILDED
Sbjct:    1 MANRTVKDAHTLHGTNPQYLVEKIIRSRIYECQFWKEHCFALTSELLVDKAVELKYIGGTYGGLTKPTPFICLVLKMLQIQPDKDIVIEFIKQEDYKYARALGAFYLRLVGESVEIYKYLEALYNDFRKLKQQDTTGKFSIVRMDEFIDQLLNEERVCDVILPRLQKRSVLEDNNALEPRQSILDED 187
[Close]
BLAST of Pre-mRNA-splicing factor 38A vs. TrEMBL
Match: A0A0R3X512 (Uncharacterized protein OS=Hydatigena taeniaeformis OX=6205 GN=TTAC_LOCUS8516 PE=4 SV=1)

HSP 1 Score: 297.36 bits (760), Expect = 2.781e-96
Identity = 137/187 (73.26%), Postives = 159/187 (85.03%), Query Frame = 3 
Query:   33 MANRTVGDAHTIHGKNPQNLIEKVIRTRIYECRYWKEECFALTSELLVDKACELRYIGGVYGGNNIPTPFLCLLQKMLQIQPDKDIVIEFIKRNEFKYCRALGALYLRLTGDSTEIFKYLETLYNDYSKLKRQEESGKFVIVHMDEFIDELMRSDRVCSIILPRLQKRHVLESGNHLEPRISILDED 593
            MANRTV DAHT+HG NPQ LIEK+IR+RIYEC++WKE CFALTSELLVDKA EL+YIGG YGG   PTPF+CL+ KMLQIQPDKDIVIEFIK+ ++KY RALGA YLRL G+S EI+KYLE LYND+ KLK+Q+ +GKF I+ MDEFID+L+  +RVC +ILPRLQKR VLE  N LEPR SILDED
Sbjct:    1 MANRTVKDAHTLHGTNPQYLIEKIIRSRIYECQFWKEHCFALTSELLVDKAVELKYIGGTYGGLTKPTPFICLVLKMLQIQPDKDIVIEFIKQEDYKYARALGAFYLRLVGESVEIYKYLEALYNDFRKLKQQDTTGKFSIIRMDEFIDQLLNEERVCDVILPRLQKRSVLEDNNALEPRQSILDED 187
[Close]
BLAST of Pre-mRNA-splicing factor 38A vs. TrEMBL
Match: A0A0R3W616 (Uncharacterized protein OS=Taenia asiatica OX=60517 GN=TASK_LOCUS5606 PE=4 SV=1)

HSP 1 Score: 295.819 bits (756), Expect = 4.383e-96
Identity = 137/187 (73.26%), Postives = 159/187 (85.03%), Query Frame = 3 
Query:   33 MANRTVGDAHTIHGKNPQNLIEKVIRTRIYECRYWKEECFALTSELLVDKACELRYIGGVYGGNNIPTPFLCLLQKMLQIQPDKDIVIEFIKRNEFKYCRALGALYLRLTGDSTEIFKYLETLYNDYSKLKRQEESGKFVIVHMDEFIDELMRSDRVCSIILPRLQKRHVLESGNHLEPRISILDED 593
            MANRTV DAHT+HG NPQ L+EK+IR+RIYEC++WKE CFALTSELLVDKA EL+YIGG YGG   PTPF+CL+ KMLQIQPDKDIVIEFIK+ ++KY RALGA YLRL G+S EI+KYLE LYND+ KLK+Q+ +GKF IV MDEFID+L+  +RVC +ILPRLQKR VLE  N LEPR SILDED
Sbjct:    1 MANRTVKDAHTLHGTNPQYLVEKIIRSRIYECQFWKEHCFALTSELLVDKAVELKYIGGTYGGLTKPTPFICLVLKMLQIQPDKDIVIEFIKQEDYKYARALGAFYLRLVGESVEIYKYLEALYNDFRKLKQQDTTGKFSIVRMDEFIDQLLNEERVCDVILPRLQKRSVLEDNNALEPRQSILDED 187
[Close]
BLAST of Pre-mRNA-splicing factor 38A vs. TrEMBL
Match: A0A5K3FQW8 (Uncharacterized protein OS=Mesocestoides corti OX=53468 PE=4 SV=1)

HSP 1 Score: 295.434 bits (755), Expect = 1.796e-95
Identity = 136/187 (72.73%), Postives = 159/187 (85.03%), Query Frame = 3 
Query:   33 MANRTVGDAHTIHGKNPQNLIEKVIRTRIYECRYWKEECFALTSELLVDKACELRYIGGVYGGNNIPTPFLCLLQKMLQIQPDKDIVIEFIKRNEFKYCRALGALYLRLTGDSTEIFKYLETLYNDYSKLKRQEESGKFVIVHMDEFIDELMRSDRVCSIILPRLQKRHVLESGNHLEPRISILDED 593
            MANRTV DAHT+HG NPQ LIEK+IR+RIYEC++WKE CFALTSELLVDKA EL+Y+GG Y G N PTPFLCL+ KMLQIQPDKDIVIEFIK+ ++KY RALGA YLRL G+S EI+KYLE LYND+ KLK+Q+ +GKF I+ MDEFID+L+  +RVC +ILPRLQKR VLE  N LEPR S+LDED
Sbjct:    1 MANRTVKDAHTLHGTNPQYLIEKIIRSRIYECQFWKEHCFALTSELLVDKAVELKYVGGTYSGLNKPTPFLCLVLKMLQIQPDKDIVIEFIKQEDYKYARALGAFYLRLVGESVEIYKYLEALYNDFRKLKQQDTAGKFSIIRMDEFIDQLLNEERVCDVILPRLQKRSVLEDNNTLEPRQSLLDED 187
[Close]
BLAST of Pre-mRNA-splicing factor 38A vs. TrEMBL
Match: A0A0R3U8G8 (Uncharacterized protein OS=Mesocestoides corti OX=53468 GN=MCOS_LOCUS3172 PE=4 SV=1)

HSP 1 Score: 294.664 bits (753), Expect = 1.955e-95
Identity = 136/187 (72.73%), Postives = 159/187 (85.03%), Query Frame = 3 
Query:   33 MANRTVGDAHTIHGKNPQNLIEKVIRTRIYECRYWKEECFALTSELLVDKACELRYIGGVYGGNNIPTPFLCLLQKMLQIQPDKDIVIEFIKRNEFKYCRALGALYLRLTGDSTEIFKYLETLYNDYSKLKRQEESGKFVIVHMDEFIDELMRSDRVCSIILPRLQKRHVLESGNHLEPRISILDED 593
            MANRTV DAHT+HG NPQ LIEK+IR+RIYEC++WKE CFALTSELLVDKA EL+Y+GG Y G N PTPFLCL+ KMLQIQPDKDIVIEFIK+ ++KY RALGA YLRL G+S EI+KYLE LYND+ KLK+Q+ +GKF I+ MDEFID+L+  +RVC +ILPRLQKR VLE  N LEPR S+LDED
Sbjct:    1 MANRTVKDAHTLHGTNPQYLIEKIIRSRIYECQFWKEHCFALTSELLVDKAVELKYVGGTYSGLNKPTPFLCLVLKMLQIQPDKDIVIEFIKQEDYKYARALGAFYLRLVGESVEIYKYLEALYNDFRKLKQQDTAGKFSIIRMDEFIDQLLNEERVCDVILPRLQKRSVLEDNNTLEPRQSLLDED 187
[Close]
BLAST of Pre-mRNA-splicing factor 38A vs. Ensembl Cavefish
Match: prpf38a (pre-mRNA processing factor 38A [Source:NCBI gene;Acc:103031029])

HSP 1 Score: 276.944 bits (707), Expect = 2.159e-91
Identity = 127/187 (67.91%), Postives = 155/187 (82.89%), Query Frame = 3 
Query:   33 MANRTVGDAHTIHGKNPQNLIEKVIRTRIYECRYWKEECFALTSELLVDKACELRYIGGVYGGNNIPTPFLCLLQKMLQIQPDKDIVIEFIKRNEFKYCRALGALYLRLTGDSTEIFKYLETLYNDYSKLKRQEESGKFVIVHMDEFIDELMRSDRVCSIILPRLQKRHVLESGNHLEPRISILDED 593
            MANRTV DA++IHG NPQ L+EK+IRTRIYE +YWKEECF LT+EL+VDKA EL+++GGVYGGN  PTPFLCL  KMLQIQP+KDI++EFIK  +FKY R LGA Y+RLTG S + +KYLE LYNDY K+K Q  +G+F I+H+DEFIDEL+ ++RVC +ILPRLQKR VLE    L+PRIS L+ED
Sbjct:    1 MANRTVKDANSIHGTNPQYLVEKIIRTRIYESKYWKEECFGLTAELVVDKAMELKFVGGVYGGNIKPTPFLCLTLKMLQIQPEKDIIVEFIKNEDFKYVRLLGATYMRLTGTSVDCYKYLEPLYNDYRKIKTQNRNGEFEIMHVDEFIDELLHAERVCDVILPRLQKRQVLEEAELLDPRISALEED 187
[Close]
BLAST of Pre-mRNA-splicing factor 38A vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006154.1 (pep scaffold:Pmarinus_7.0:GL476888:182281:184110:1 gene:ENSPMAG00000005561.1 transcript:ENSPMAT00000006154.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 215.312 bits (547), Expect = 1.661e-70
Identity = 98/137 (71.53%), Postives = 116/137 (84.67%), Query Frame = 3 
Query:   33 MANRTVGDAHTIHGKNPQNLIEKVIRTRIYECRYWKEECFALTSELLVDKACELRYIGGVYGGNNIPTPFLCLLQKMLQIQPDKDIVIEFIKRNEFKYCRALGALYLRLTGDSTEIFKYLETLYNDYSKLKRQEESG 443
            MANRTV DAH+I G NPQ L+EK+IRTRIYE +YWKEECFALT+EL+VDKA ELR++GGVYGGN  PTPFLCL+ KMLQIQP+KDIV+EFI+  +FKY R LGA+Y+RLTG   + +KYLE LYNDY K+KRQ  SG
Sbjct:    1 MANRTVKDAHSIRGTNPQYLVEKIIRTRIYESKYWKEECFALTAELVVDKAMELRFVGGVYGGNIKPTPFLCLVLKMLQIQPEKDIVVEFIRNEDFKYVRLLGAMYMRLTGTPMDCYKYLEPLYNDYRKIKRQARSG 137
[Close]
BLAST of Pre-mRNA-splicing factor 38A vs. Ensembl Nematostella
Match: EDO31507 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SXQ7])

HSP 1 Score: 265.003 bits (676), Expect = 7.800e-89
Identity = 121/184 (65.76%), Postives = 151/184 (82.07%), Query Frame = 3 
Query:   33 MANRTVGDAHTIHGKNPQNLIEKVIRTRIYECRYWKEECFALTSELLVDKACELRYIGGVYGGNNIPTPFLCLLQKMLQIQPDKDIVIEFIKRNEFKYCRALGALYLRLTGDSTEIFKYLETLYNDYSKLKRQEESGKFVIVHMDEFIDELMRSDRVCSIILPRLQKRHVLESGNHLEPRISIL 584
            MANRTV DA  I G NPQ L+EK+IRTRIYE +YWKE+CFALT+ELLVDKA EL +IGG +GGN  PTPFLCLL KMLQIQP+K+I++EFIK +++KY RALGA+Y+RL G + + + YLE L+NDY KLKR  ++G + +VHMDEFID+L+R DRV  IILPR+Q RH+LE+ N LEPR S+L
Sbjct:    1 MANRTVADAKNIKGTNPQYLVEKIIRTRIYESKYWKEQCFALTAELLVDKAMELDHIGGTFGGNIKPTPFLCLLLKMLQIQPEKEIIVEFIKNDDYKYVRALGAMYMRLVGTALDCYNYLEPLFNDYRKLKRMSQTGVYEVVHMDEFIDDLLREDRVNDIILPRIQARHILEATNTLEPRRSLL 184
[Close]
BLAST of Pre-mRNA-splicing factor 38A vs. Ensembl Medaka
Match: prpf38a (pre-mRNA processing factor 38A [Source:NCBI gene;Acc:101172647])

HSP 1 Score: 275.789 bits (704), Expect = 4.852e-91
Identity = 124/187 (66.31%), Postives = 156/187 (83.42%), Query Frame = 3 
Query:   33 MANRTVGDAHTIHGKNPQNLIEKVIRTRIYECRYWKEECFALTSELLVDKACELRYIGGVYGGNNIPTPFLCLLQKMLQIQPDKDIVIEFIKRNEFKYCRALGALYLRLTGDSTEIFKYLETLYNDYSKLKRQEESGKFVIVHMDEFIDELMRSDRVCSIILPRLQKRHVLESGNHLEPRISILDED 593
            MANRTV DA++IHG NPQ L+EK+IRTRIYE +YWKEECF LT+EL+VDKA EL+++GGVYGGN  PTPFLCL  KMLQIQP+KDI++EFIK  +FKY R LGA+Y+RLTG + + +KYLE LYNDY K+K Q  +G+F ++H+DEFIDEL+ ++RVC IILPRLQ+R VLE    L+PR+S L+ED
Sbjct:    1 MANRTVKDANSIHGTNPQYLVEKIIRTRIYESKYWKEECFGLTAELVVDKAMELKFVGGVYGGNIKPTPFLCLTLKMLQIQPEKDIIVEFIKNEDFKYVRLLGAMYMRLTGTAVDCYKYLEPLYNDYRKIKTQNRNGEFELMHVDEFIDELLHAERVCDIILPRLQRRQVLEEAEMLDPRVSALEED 187
[Close]
BLAST of Pre-mRNA-splicing factor 38A vs. Ensembl Medaka
Match: prpf38a (pre-mRNA processing factor 38A [Source:NCBI gene;Acc:101172647])

HSP 1 Score: 274.633 bits (701), Expect = 8.948e-91
Identity = 124/187 (66.31%), Postives = 156/187 (83.42%), Query Frame = 3 
Query:   33 MANRTVGDAHTIHGKNPQNLIEKVIRTRIYECRYWKEECFALTSELLVDKACELRYIGGVYGGNNIPTPFLCLLQKMLQIQPDKDIVIEFIKRNEFKYCRALGALYLRLTGDSTEIFKYLETLYNDYSKLKRQEESGKFVIVHMDEFIDELMRSDRVCSIILPRLQKRHVLESGNHLEPRISILDED 593
            MANRTV DA++IHG NPQ L+EK+IRTRIYE +YWKEECF LT+EL+VDKA EL+++GGVYGGN  PTPFLCL  KMLQIQP+KDI++EFIK  +FKY R LGA+Y+RLTG + + +KYLE LYNDY K+K Q  +G+F ++H+DEFIDEL+ ++RVC IILPRLQ+R VLE    L+PR+S L+ED
Sbjct:    1 MANRTVKDANSIHGTNPQYLVEKIIRTRIYESKYWKEECFGLTAELVVDKAMELKFVGGVYGGNIKPTPFLCLTLKMLQIQPEKDIIVEFIKNEDFKYVRLLGAMYMRLTGTAVDCYKYLEPLYNDYRKIKTQNRNGEFELMHVDEFIDELLHAERVCDIILPRLQRRQVLEEAEMLDPRVSALEED 187
[Close]
BLAST of Pre-mRNA-splicing factor 38A vs. Ensembl Medaka
Match: prpf38a (pre-mRNA processing factor 38A [Source:NCBI gene;Acc:101172647])

HSP 1 Score: 273.478 bits (698), Expect = 1.428e-90
Identity = 124/187 (66.31%), Postives = 156/187 (83.42%), Query Frame = 3 
Query:   33 MANRTVGDAHTIHGKNPQNLIEKVIRTRIYECRYWKEECFALTSELLVDKACELRYIGGVYGGNNIPTPFLCLLQKMLQIQPDKDIVIEFIKRNEFKYCRALGALYLRLTGDSTEIFKYLETLYNDYSKLKRQEESGKFVIVHMDEFIDELMRSDRVCSIILPRLQKRHVLESGNHLEPRISILDED 593
            MANRTV DA++IHG NPQ L+EK+IRTRIYE +YWKEECF LT+EL+VDKA EL+++GGVYGGN  PTPFLCL  KMLQIQP+KDI++EFIK  +FKY R LGA+Y+RLTG + + +KYLE LYNDY K+K Q  +G+F ++H+DEFIDEL+ ++RVC IILPRLQ+R VLE    L+PR+S L+ED
Sbjct:    1 MANRTVKDANSIHGTNPQYLVEKIIRTRIYESKYWKEECFGLTAELVVDKAMELKFVGGVYGGNIKPTPFLCLTLKMLQIQPEKDIIVEFIKNEDFKYVRLLGAMYMRLTGTAVDCYKYLEPLYNDYRKIKTQNRNGEFELMHVDEFIDELLHAERVCDIILPRLQRRQVLEEAEMLDPRVSALEED 187
[Close]
BLAST of Pre-mRNA-splicing factor 38A vs. Ensembl Medaka
Match: prpf38a (pre-mRNA processing factor 38A [Source:NCBI gene;Acc:101172647])

HSP 1 Score: 274.248 bits (700), Expect = 1.602e-90
Identity = 124/187 (66.31%), Postives = 156/187 (83.42%), Query Frame = 3 
Query:   33 MANRTVGDAHTIHGKNPQNLIEKVIRTRIYECRYWKEECFALTSELLVDKACELRYIGGVYGGNNIPTPFLCLLQKMLQIQPDKDIVIEFIKRNEFKYCRALGALYLRLTGDSTEIFKYLETLYNDYSKLKRQEESGKFVIVHMDEFIDELMRSDRVCSIILPRLQKRHVLESGNHLEPRISILDED 593
            MANRTV DA++IHG NPQ L+EK+IRTRIYE +YWKEECF LT+EL+VDKA EL+++GGVYGGN  PTPFLCL  KMLQIQP+KDI++EFIK  +FKY R LGA+Y+RLTG + + +KYLE LYNDY K+K Q  +G+F ++H+DEFIDEL+ ++RVC IILPRLQ+R VLE    L+PR+S L+ED
Sbjct:    1 MANRTVKDANSIHGTNPQYLVEKIIRTRIYESKYWKEECFGLTAELVVDKAMELKFVGGVYGGNIKPTPFLCLTLKMLQIQPEKDIIVEFIKNEDFKYVRLLGAMYMRLTGTAVDCYKYLEPLYNDYRKIKTQNRNGEFELMHVDEFIDELLHAERVCDIILPRLQRRQVLEEAEMLDPRVSALEED 187
[Close]
BLAST of Pre-mRNA-splicing factor 38A vs. Ensembl Medaka
Match: prpf38a (pre-mRNA processing factor 38A [Source:NCBI gene;Acc:101172647])

HSP 1 Score: 274.248 bits (700), Expect = 1.602e-90
Identity = 124/187 (66.31%), Postives = 156/187 (83.42%), Query Frame = 3 
Query:   33 MANRTVGDAHTIHGKNPQNLIEKVIRTRIYECRYWKEECFALTSELLVDKACELRYIGGVYGGNNIPTPFLCLLQKMLQIQPDKDIVIEFIKRNEFKYCRALGALYLRLTGDSTEIFKYLETLYNDYSKLKRQEESGKFVIVHMDEFIDELMRSDRVCSIILPRLQKRHVLESGNHLEPRISILDED 593
            MANRTV DA++IHG NPQ L+EK+IRTRIYE +YWKEECF LT+EL+VDKA EL+++GGVYGGN  PTPFLCL  KMLQIQP+KDI++EFIK  +FKY R LGA+Y+RLTG + + +KYLE LYNDY K+K Q  +G+F ++H+DEFIDEL+ ++RVC IILPRLQ+R VLE    L+PR+S L+ED
Sbjct:    1 MANRTVKDANSIHGTNPQYLVEKIIRTRIYESKYWKEECFGLTAELVVDKAMELKFVGGVYGGNIKPTPFLCLTLKMLQIQPEKDIIVEFIKNEDFKYVRLLGAMYMRLTGTAVDCYKYLEPLYNDYRKIKTQNRNGEFELMHVDEFIDELLHAERVCDIILPRLQRRQVLEEAEMLDPRVSALEED 187
[Close]
BLAST of Pre-mRNA-splicing factor 38A vs. Planmine SMEST
Match: SMESG000012763.1 (SMESG000012763.1)

HSP 1 Score: 392.119 bits (1006), Expect = 2.177e-138
Identity = 208/211 (98.58%), Postives = 209/211 (99.05%), Query Frame = 3 
Query:   33 MANRTVGDAHTIHGKNPQNLIEKVIRTRIYECRYWKEECFALTSELLVDKACELRYIGGVYGGNNIPTPFLCLLQKMLQIQPDKDIVIEFIKRNEFKYCRALGALYLRLTGDSTEIFKYLETLYNDYSKLKRQEESGKFVIVHMDEFIDELMRSDRVCSIILPRLQKRHVLESGNHLEPRISILDEDXXXXXXXXXXXXXXXXXNKKRAEK 665
            MANRTVGDAHTIHGKNPQNLIEKVIRTRIYECRYWKEECFALTSELLVDKACELRYIGGVYGGNNIPTPFLCLLQKMLQIQPDKDIVIEFIKRNEFKYCRALGALYLRLTGDSTEIFKYLETLYNDYSKLKRQEESGKFVIVHMDEFIDELMRSDRVCSIILPRLQKRHVLESGNHLEPRISILDEDLQELMLQAVEEEEELEENKK + K
Sbjct:    1 MANRTVGDAHTIHGKNPQNLIEKVIRTRIYECRYWKEECFALTSELLVDKACELRYIGGVYGGNNIPTPFLCLLQKMLQIQPDKDIVIEFIKRNEFKYCRALGALYLRLTGDSTEIFKYLETLYNDYSKLKRQEESGKFVIVHMDEFIDELMRSDRVCSIILPRLQKRHVLESGNHLEPRISILDEDLQELMLQAVEEEEELEENKKASRK 211
[Close]
BLAST of Pre-mRNA-splicing factor 38A vs. Planmine SMEST
Match: SMESG000050016.1 (SMESG000050016.1)

HSP 1 Score: 326.635 bits (836), Expect = 3.692e-111
Identity = 153/187 (81.82%), Postives = 171/187 (91.44%), Query Frame = 3 
Query:   33 MANRTVGDAHTIHGKNPQNLIEKVIRTRIYECRYWKEECFALTSELLVDKACELRYIGGVYGGNNIPTPFLCLLQKMLQIQPDKDIVIEFIKRNEFKYCRALGALYLRLTGDSTEIFKYLETLYNDYSKLKRQEESGKFVIVHMDEFIDELMRSDRVCSIILPRLQKRHVLESGNHLEPRISILDED 593
            MANRTVGDAHTIHGKNPQ+LIEKVIRTRIYE  +WKEECFALTSELLVDKA EL++IGGVY G+N  TPFLCLL KMLQIQP+KDIVIEF++RNEFKY RAL A YLRLTGD+TEI+KYLE LYNDYSKLK QEE+GKF I+HMD+FIDEL+R+DRVC+IILPR+QKR VLESGN L PR+SILDED
Sbjct:    1 MANRTVGDAHTIHGKNPQSLIEKVIRTRIYESMFWKEECFALTSELLVDKAVELKFIGGVYSGSNKATPFLCLLLKMLQIQPEKDIVIEFLRRNEFKYSRALAAFYLRLTGDATEIYKYLEPLYNDYSKLKFQEENGKFSILHMDDFIDELLRNDRVCTIILPRIQKRDVLESGNFLGPRLSILDED 187
[Close]
BLAST of Pre-mRNA-splicing factor 38A vs. Planmine SMEST
Match: SMESG000012773.1 (SMESG000012773.1)

HSP 1 Score: 326.635 bits (836), Expect = 3.692e-111
Identity = 153/187 (81.82%), Postives = 171/187 (91.44%), Query Frame = 3 
Query:   33 MANRTVGDAHTIHGKNPQNLIEKVIRTRIYECRYWKEECFALTSELLVDKACELRYIGGVYGGNNIPTPFLCLLQKMLQIQPDKDIVIEFIKRNEFKYCRALGALYLRLTGDSTEIFKYLETLYNDYSKLKRQEESGKFVIVHMDEFIDELMRSDRVCSIILPRLQKRHVLESGNHLEPRISILDED 593
            MANRTVGDAHTIHGKNPQ+LIEKVIRTRIYE  +WKEECFALTSELLVDKA EL++IGGVY G+N  TPFLCLL KMLQIQP+KDIVIEF++RNEFKY RAL A YLRLTGD+TEI+KYLE LYNDYSKLK QEE+GKF I+HMD+FIDEL+R+DRVC+IILPR+QKR VLESGN L PR+SILDED
Sbjct:    1 MANRTVGDAHTIHGKNPQSLIEKVIRTRIYESMFWKEECFALTSELLVDKAVELKFIGGVYSGSNKATPFLCLLLKMLQIQPEKDIVIEFLRRNEFKYSRALAAFYLRLTGDATEIYKYLEPLYNDYSKLKFQEENGKFSILHMDDFIDELLRNDRVCTIILPRIQKRDVLESGNFLGPRLSILDED 187
The following BLAST results are available for this feature:
BLAST of Pre-mRNA-splicing factor 38A vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 1
Match NameE-valueIdentityDescription
PRPF38A3.182e-9469.52pre-mRNA processing factor 38A [Source:HGNC Symbol... [more]
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BLAST of Pre-mRNA-splicing factor 38A vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 1
Match NameE-valueIdentityDescription
prp-381.861e-8164.17Yeast PRP (Splicing factor) related [Source:UniPr... [more]
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BLAST of Pre-mRNA-splicing factor 38A vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 1
Match NameE-valueIdentityDescription
Prp384.993e-9268.45gene:FBgn0050342 transcript:FBtr0088582[more]
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BLAST of Pre-mRNA-splicing factor 38A vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 2
Match NameE-valueIdentityDescription
prpf38a1.769e-9166.84pre-mRNA processing factor 38A [Source:NCBI gene;A... [more]
prpf38a3.378e-9166.84pre-mRNA processing factor 38A [Source:NCBI gene;A... [more]
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BLAST of Pre-mRNA-splicing factor 38A vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 1
Match NameE-valueIdentityDescription
prpf38a2.737e-9267.38pre-mRNA processing factor 38A [Source:NCBI gene;A... [more]
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BLAST of Pre-mRNA-splicing factor 38A vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 1
Match NameE-valueIdentityDescription
Prpf38a1.091e-9368.98PRP38 pre-mRNA processing factor 38 (yeast) domain... [more]
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BLAST of Pre-mRNA-splicing factor 38A vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q5RDD2|PR38A_PONAB1.528e-9369.52Pre-mRNA-splicing factor 38A OS=Pongo abelii OX=96... [more]
sp|Q8HXH6|PR38A_MACFA1.528e-9369.52Pre-mRNA-splicing factor 38A OS=Macaca fasciculari... [more]
sp|Q8NAV1|PR38A_HUMAN1.528e-9369.52Pre-mRNA-splicing factor 38A OS=Homo sapiens OX=96... [more]
sp|Q0P5I6|PR38A_BOVIN1.528e-9369.52Pre-mRNA-splicing factor 38A OS=Bos taurus OX=9913... [more]
sp|Q4FK66|PR38A_MOUSE7.632e-9368.98Pre-mRNA-splicing factor 38A OS=Mus musculus OX=10... [more]
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BLAST of Pre-mRNA-splicing factor 38A vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
W6UMV22.761e-9673.26Pre-mRNA-splicing factor 38A OS=Echinococcus granu... [more]
A0A0R3X5122.781e-9673.26Uncharacterized protein OS=Hydatigena taeniaeformi... [more]
A0A0R3W6164.383e-9673.26Uncharacterized protein OS=Taenia asiatica OX=6051... [more]
A0A5K3FQW81.796e-9572.73Uncharacterized protein OS=Mesocestoides corti OX=... [more]
A0A0R3U8G81.955e-9572.73Uncharacterized protein OS=Mesocestoides corti OX=... [more]
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BLAST of Pre-mRNA-splicing factor 38A vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 1
Match NameE-valueIdentityDescription
prpf38a2.159e-9167.91pre-mRNA processing factor 38A [Source:NCBI gene;A... [more]
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BLAST of Pre-mRNA-splicing factor 38A vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1
Match NameE-valueIdentityDescription
ENSPMAT00000006154.11.661e-7071.53pep scaffold:Pmarinus_7.0:GL476888:182281:184110:1... [more]
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BLAST of Pre-mRNA-splicing factor 38A vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Pre-mRNA-splicing factor 38A vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1
Match NameE-valueIdentityDescription
EDO315077.800e-8965.76Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Pre-mRNA-splicing factor 38A vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
prpf38a4.852e-9166.31pre-mRNA processing factor 38A [Source:NCBI gene;A... [more]
prpf38a8.948e-9166.31pre-mRNA processing factor 38A [Source:NCBI gene;A... [more]
prpf38a1.428e-9066.31pre-mRNA processing factor 38A [Source:NCBI gene;A... [more]
prpf38a1.602e-9066.31pre-mRNA processing factor 38A [Source:NCBI gene;A... [more]
prpf38a1.602e-9066.31pre-mRNA processing factor 38A [Source:NCBI gene;A... [more]
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BLAST of Pre-mRNA-splicing factor 38A vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 3
Match NameE-valueIdentityDescription
SMESG000012763.12.177e-13898.58SMESG000012763.1[more]
SMESG000050016.13.692e-11181.82SMESG000050016.1[more]
SMESG000012773.13.692e-11181.82SMESG000012773.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30018486 ID=SMED30018486|Name=Pre-mRNA-splicing factor 38A|organism=Schmidtea mediterranea sexual|type=transcript|length=1057bp
GTTTAAATAATATAACATAATTTTTTCTAAATATGGCAAATAGAACTGTT
GGTGATGCTCATACTATTCATGGTAAAAATCCACAGAATCTTATCGAAAA
AGTTATTAGAACGAGAATTTATGAGTGTAGATATTGGAAAGAAGAATGTT
TCGCATTAACATCTGAACTTTTGGTTGACAAAGCCTGTGAATTAAGATAT
ATTGGAGGCGTTTATGGGGGAAATAATATACCAACTCCATTTCTATGTCT
ATTACAGAAGATGCTTCAGATTCAACCAGATAAAGATATTGTTATTGAAT
TTATCAAACGAAATGAATTCAAATATTGTCGAGCTCTTGGAGCATTGTAT
CTACGTCTGACTGGCGACTCAACGGAAATATTTAAATATTTAGAAACGTT
ATACAATGATTATTCCAAGTTAAAGAGACAAGAAGAAAGTGGAAAGTTTG
TCATAGTTCATATGGATGAATTTATCGATGAATTGATGCGCAGTGACAGA
GTTTGTAGTATCATTTTACCCCGTCTTCAAAAACGACATGTTCTTGAATC
AGGTAATCATCTTGAACCAAGAATATCGATTCTCGATGAAGATTTACAAG
AATTGATGTTGCAAGCAGTCGAAGAAGAAGAAGAATTAGAAGAAAATAAA
AAACGAGCAGAAAAGCGAATTGAAGAAGATTCTAATCATCGGAGATATAG
TCGATCACGAAGTCGAGATAGAGACCGAGAAAGACCGCCACGTCGACGAT
CAAGAACTCGTTCTAGATCTAAAGATAAATCTCGTAGAAAATCACCGAAG
CGTGAACATAAGGAAAGGAAACATGACAGAAGAGATCGATCGAGATCCGC
AGAAAAACGAGATCGTGGATATGACAGAGAATCACCTGATCGTATTAAAC
GAGAGAAAAAGACCGAACGTAGAGACAAAGACAGAGAACGAGATAGAAAT
AGAGATAGGCACTGAATAGTTTTTATTTTTGTTTTAATTATGTAATTATT
GAAAATTCCTTACTATTCAAATATATGAATTTTGTTGAGTTTTTAAATAT
ATCTTAT
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protein sequence of SMED30018486-orf-1

>SMED30018486-orf-1 ID=SMED30018486-orf-1|Name=SMED30018486-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=311bp
MANRTVGDAHTIHGKNPQNLIEKVIRTRIYECRYWKEECFALTSELLVDK
ACELRYIGGVYGGNNIPTPFLCLLQKMLQIQPDKDIVIEFIKRNEFKYCR
ALGALYLRLTGDSTEIFKYLETLYNDYSKLKRQEESGKFVIVHMDEFIDE
LMRSDRVCSIILPRLQKRHVLESGNHLEPRISILDEDLQELMLQAVEEEE
ELEENKKRAEKRIEEDSNHRRYSRSRSRDRDRERPPRRRSRTRSRSKDKS
RRKSPKREHKERKHDRRDRSRSAEKRDRGYDRESPDRIKREKKTERRDKD
RERDRNRDRH*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: biological process
TermDefinition
GO:0000398mRNA splicing, via spliceosome
GO:0008380RNA splicing
GO:0006397mRNA processing
Vocabulary: cellular component
TermDefinition
GO:0071005U2-type precatalytic spliceosome
GO:0005634nucleus
GO:0005681spliceosomal complex
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000101muscle cell
PLANA:0000429neoblast
PLANA:0002109X1 cell
PLANA:0002111X2 cell
PLANA:0003001lateral region of the whole animal
Vocabulary: INTERPRO
TermDefinition
IPR005037PRP38