XK-related protein

Overview
NameXK-related protein
Smed IDSMED30018439
Length (bp)2446
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of XK-related protein (SMED30018439) t-SNE clustered cells

Violin plots show distribution of expression levels for XK-related protein (SMED30018439) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of XK-related protein (SMED30018439) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for XK-related protein (SMED30018439) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30018439

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 10

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
pharynxSMED30018439h1SMcG0003735 dd_Smed_v4_2770_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
protonephridiaSMED30018439h1SMcG0003735 dd_Smed_v4_2770_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
nervous systemSMED30018439h1SMcG0003735 dd_Smed_v4_2770_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
gutSMED30018439h1SMcG0003735 dd_Smed_v4_2770_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30018439h1SMcG0003735 dd_Smed_v4_2770_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30018439h1SMcG0003735 dd_Smed_v4_2770_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymaSMED30018439h1SMcG0003735 dd_Smed_v4_2770_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
non-ciliated neuronSMED30018439h1SMcG0003735 dd_Smed_v4_2770_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30018439h1SMcG0003735 dd_Smed_v4_2770_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017		whole organism asexual adult single-cell RNA-sequencing evidence
Category 4 cellSMED30018439h1SMcG0003735 dd_Smed_v4_2770_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017		whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of XK-related protein vs. TrEMBL
Match: A0A5J4NJL5 (XK-related protein OS=Paragonimus westermani OX=34504 GN=DEA37_0007859 PE=3 SV=1)

HSP 1 Score: 236.498 bits (602), Expect = 4.844e-63
Identity = 153/420 (36.43%), Postives = 240/420 (57.14%), Query Frame = 1 
Query:  142 EDLVSDRSIPLKICMIVLNCFQIISSWIAVCFFFTSIQEWTPMEVGVSGGILIFGNYIVPGIANGIIYWKRWKRSTPGYRRRMEEENKQAWVCLRIALSLLGIPTVGRYIETIMVSRKLDDLEKKHLHASVNTHKEGSQLNPVGTSRLGSIINQKNLERMSKSGINQSVISGATQTYNINGMNENSQDKVRKARRQYKRCEHDXXXXXXXXXXXXXXXXXXXFAVLYLQRIE-RINMSVDQGSAVIVAAILNVLWLSATLTHFYPSRHVQSEAEFERGVSTSNIGAIILLYLSHLIQVVLRIICLAIFANWFTYYVLIVIGFHWIVGLVILIVYRFHMKAKTLGKSMISCSS----FLSALFFGYVGIFDFVNGNEGKTXXXXXXXXXXXXIENIFMLVLWIAKFPTTQIRYPIPFVCVI 1386
            +DL+SDR+I  K+  IVL+   ++++W  +     +    T +EV VS  +LI G Y+  GI +G +YW+RW +++     R +EENK+AWVC+RI LSLLG+  V RYI++++V R++  LEK++L  +V   KE  Q + + +   GS+I+   +     + I  +  +       +  ++     +V K RRQ++R E D A +AL +GV GAGP  I+  VLY +R+    +M++     ++  ++  ++W+ A LTHF+P+   QSE EFERG+    I  +ILL+ +HL+ V LR  CL +F   F + VL V+GFH +  L+ LIV R   +      S  + SS     LS + F YVG+F+F N     TR RY ++Y FYY+EN  M+  W   F   Q+ Y +P + VI
Sbjct:   24 DDLISDRAIWRKVVCIVLSIVFLLNAWAVIVLHLVNFTNETVLEVSVSVAVLIAGQYVGTGIVDGYLYWRRWSKTSHKSHSREQEENKEAWVCMRITLSLLGMAPVSRYIDSLVVVRRMLGLEKQYLSEAVAFAKEAKQPSNLPS---GSLISAPTMSVKQSTSIKSNNTNQPMSASRLRALDAG-LVRVYKVRRQFRRTEQDAALVALASGVVGAGPFVISQGVLYFRRVGLNYSMALTTMLGILSCSVTGLVWVCAGLTHFHPAAFDQSEVEFERGIGQVPISGLILLFFTHLVHVTLRSGCLMLFTAQFYWIVLGVLGFHLLFVLLCLIVARLCTREDYSNPSQANRSSISGNLLSDIMFSYVGLFEFANAYAKYTRTRYFLYYFFYYLENAAMIGAWYVHFTYPQMWYYLPALLVI 439
[Close]
BLAST of XK-related protein vs. TrEMBL
Match: A0A1S8WRM4 (XK-related protein (Fragment) OS=Opisthorchis viverrini OX=6198 GN=X801_07008 PE=3 SV=1)

HSP 1 Score: 219.164 bits (557), Expect = 2.208e-57
Identity = 157/418 (37.56%), Postives = 229/418 (54.78%), Query Frame = 1 
Query:  142 EDLVSDRSIPLKICMIVLNCFQIISSWIAVCFFFTSIQEWTPMEVGVSGGILIFGNYIVPGIANGIIYWKRWKRSTPGYRRRMEEENKQAWVCLRIALSLLGIPTVGRYIETIMVSRKLDDLEKKHLHASVNTHKEGSQLNPVGTSRLGSIINQKNLERMSKSGINQSVISGATQTYNINGMNENSQDKVR--KARRQYKRCEHDXXXXXXXXXXXXXXXXXXXFAVLYLQRIE-RINMSVDQGSAVIVAAILNVLWLSATLTHFYPSRHVQSEAEFERGVSTSNIGAIILLYLSHLIQVVLRIICLAIFANWFTYYVLIVIGFHWIVGLVILIVYRFHMKAK-----TLGKSMISCSSFLSALFFGYVGIFDFVNGNEGKTXXXXXXXXXXXXIENIFMLVLWIAKFPTTQIRYPIP 1371
            +DL+SDR+I  K+  I+L    ++S+WI V          T +EV V+   L+ G Y+  GI +   YW RW  ++     + +EENK+AWVC+RI L+L+G+  V RYIE+++V R++ DLEK++L  +V   KE  Q + + +   GS+I+  +L         QS    A  + N     E     VR  K RRQ++R E D A +AL +GV GAGP   +  VL+ +R+     M+ D    V+   I  V+WL A LTH+YP+ + QSE +F+RGV     G + LLY +HL+ V LR+  L +F   F + V+ V+ FH+   L  LIV R    A       L +S IS  + LS   F YVG+F+F N     TR RYL++Y FYY+EN  M+  W   F   Q+ Y +P
Sbjct:   25 DDLISDRAIWRKVTCIILCLVFVLSAWIMVVLHVVHFTNQTILEVSVTVVTLLIGQYLATGIFDCYRYWMRWNTASKKPHSKQQEENKEAWVCMRITLALMGLAPVSRYIESLVVVRRMIDLEKRYLAEAVAFAKEVKQPSTLPS---GSLISGPSL------ATRQS--EAAASSKNAARFRELDAGLVRVYKVRRQFRRTEQDAALVALASGVLGAGPFVFSQGVLFFRRVGLNFPMTDDAMVGVLSCTITGVVWLCAGLTHYYPAAYDQSEFDFDRGVGQVPAGGLALLYSAHLVHVTLRLGTLVLFTAQFYWIVMAVVAFHYFFVLFSLIVSRACTSADYSNQVKLERSSIS-GNLLSDFMFAYVGLFEFANAYAKYTRTRYLLYYFFYYLENSAMIGAWYVHFTYPQVWYYLP 430
[Close]
BLAST of XK-related protein vs. TrEMBL
Match: A0A075A987 (XK-related protein OS=Opisthorchis viverrini OX=6198 GN=T265_01708 PE=3 SV=1)

HSP 1 Score: 218.779 bits (556), Expect = 5.498e-57
Identity = 157/422 (37.20%), Postives = 231/422 (54.74%), Query Frame = 1 
Query:  142 EDLVSDRSIPLKICMIVLNCFQIISSWIAVCFFFTSIQEWTPMEVGVSGGILIFGNYIVPGIANGIIYWKRWKRSTPGYRRRMEEENKQAWVCLRIALSLLGIPTVGRYIETIMVSRKLDDLEKKHLHASVNTHKEGSQLNPVGTSRLGSIINQKNLERMSKSGINQSVISGATQTYNINGMNENSQDKVR--KARRQYKRCEHDXXXXXXXXXXXXXXXXXXXFAVLYLQRIE-RINMSVDQGSAVIVAAILNVLWLSATLTHFYPSRHVQSEAEFERGVSTSNIGAIILLYLSHLIQVVLRIICLAIFANWFTYYVLIVIGFHWIVGLVILIVYRFHMKAK-----TLGKSMISCSSFLSALFFGYVGIFDFVNGNEGKTXXXXXXXXXXXXIENIFMLVLWIAKFPTTQIRYPIPFVCV 1383
            +DL+SDR+I  K+  I+L    ++S+WI V          T +EV V+   L+ G Y+  GI +   YW RW  ++     + +EENK+AWVC+RI L+L+G+  V RYIE+++V R++ DLEK++L  +V   KE  Q + + +   GS+I+  +L         QS    A  + N     E     VR  K RRQ++R E D A +AL +GV GAGP   +  VL+ +R+     M+ D    V+   I  V+WL A LTH+YP+ + QSE +F+RGV     G + LLY +HL+ V LR+  L +F   F + V+ V+ FH+   L  LIV R    A       L +S IS  + LS   F YVG+F+F N     TR RYL++Y FYY+EN  M+  W   F   Q+ Y +P + +
Sbjct:   25 DDLISDRAIWRKVTCIILCLVFVLSAWIMVVLHVVHFTNQTILEVSVTVVTLLIGQYLGTGIFDCYRYWMRWNTASKKPHSKQQEENKEAWVCMRITLALMGLAPVSRYIESLVVVRRMIDLEKRYLAEAVAFAKEVKQPSTLPS---GSLISGPSL------ATRQS--EAAASSKNAARFRELDAGLVRVYKVRRQFRRTEQDAALVALASGVLGAGPFVFSQGVLFFRRVGLNFPMTDDAMVGVLSCTITGVVWLCAGLTHYYPAAYDQSEFDFDRGVGQVPAGGLALLYSAHLVHVTLRLGTLVLFTAQFYWIVMAVVAFHYFFVLFSLIVSRACTSADYSNQVKLERSSIS-GNLLSDFMFAYVGLFEFANAYAKYTRTRYLLYYFFYYLENSAMIGAWYVHFTYPQVWYYLPSLLI 434
[Close]
BLAST of XK-related protein vs. TrEMBL
Match: A0A4S2M867 (XK-related protein OS=Opisthorchis felineus OX=147828 GN=CRM22_001978 PE=3 SV=1)

HSP 1 Score: 215.312 bits (547), Expect = 1.274e-55
Identity = 156/422 (36.97%), Postives = 231/422 (54.74%), Query Frame = 1 
Query:  142 EDLVSDRSIPLKICMIVLNCFQIISSWIAVCFFFTSIQEWTPMEVGVSGGILIFGNYIVPGIANGIIYWKRWKRSTPGYRRRMEEENKQAWVCLRIALSLLGIPTVGRYIETIMVSRKLDDLEKKHLHASVNTHKEGSQLNPVGTSRLGSIINQKNLERMSKSGINQSVISGATQTYNINGMNENSQDKVR--KARRQYKRCEHDXXXXXXXXXXXXXXXXXXXFAVLYLQRIE-RINMSVDQGSAVIVAAILNVLWLSATLTHFYPSRHVQSEAEFERGVSTSNIGAIILLYLSHLIQVVLRIICLAIFANWFTYYVLIVIGFHWIVGLVILIVYRFHMKAK-----TLGKSMISCSSFLSALFFGYVGIFDFVNGNEGKTXXXXXXXXXXXXIENIFMLVLWIAKFPTTQIRYPIPFVCV 1383
            +DL+SDR++  K+  I+L    + S+WI V          T +EV V+   L+ G Y+  GI +   YW RW  ++     + +EEN++AWVC+RI L+L+G+  V RYIE+++V R++ DLEK++L  +V   KE  Q + + +   GS+I+  +L         QS    A+ + N     E     VR  K RRQ++R E D A +AL +GV GAGP  I+  VL+ +R+     M+ D    V+   I  V+WL A LTH+YP+ + QSE +F+RGV     G + LLY +HL+ V LR+    +F   F + VL V+ FH+   L  L+V R    A       L +S IS  + LS   F YVG+F+F N     TR RYL++Y FYY+EN  M+  W   F   Q+ Y +P + V
Sbjct:   43 DDLISDRAMWRKVACIILCLVFVFSAWIMVVLHVVHFTNQTVLEVSVTVVTLLIGQYLGTGIFDCYRYWIRWSTASKKPHSKQQEENRKAWVCMRITLALMGLAPVSRYIESLVVVRRMIDLEKRYLAEAVAFAKEVKQPSTLPS---GSLISGPSL------ATRQS--EAASSSKNAARFRELDAGLVRVYKVRRQFRRTEQDAALVALASGVLGAGPFVISQGVLFFRRVGLNFPMTNDAMVGVLSCTITGVVWLCAGLTHYYPAAYDQSEFDFDRGVGQVPAGGLALLYSAHLVHVTLRLGTFVLFTAQFYWIVLAVLAFHYFFVLFSLVVSRACTNADYSNPAKLERSSIS-GNLLSDFMFAYVGLFEFANAYAKYTRTRYLLYYFFYYLENSAMIGAWYVHFTYPQVWYYLPSLLV 452
[Close]
BLAST of XK-related protein vs. TrEMBL
Match: G7YC27 (XK-related protein OS=Clonorchis sinensis OX=79923 GN=CLF_104668 PE=3 SV=1)

HSP 1 Score: 213.772 bits (543), Expect = 5.511e-55
Identity = 156/421 (37.05%), Postives = 227/421 (53.92%), Query Frame = 1 
Query:  142 EDLVSDRSIPLKICMIVLNCFQIISSWIAVCFFFTSIQEWTPMEVGVSGGILIFGNYIVPGIANGIIYWKRWKRSTPGYRRRMEEENKQAWVCLRIALSLLGIPTVGRYIETIMVSRKLDDLEKKHLHASVNTHKEGSQLNPVGTSRLGSIINQKNLERMSKSGINQSVISGATQTYNINGMNENSQDKVR--KARRQYKRCEHDXXXXXXXXXXXXXXXXXXXFAVLYLQRIE-RINMSVDQGSAVIVAAILNVLWLSATLTHFYPSRHVQSEAEFERGVSTSNIGAIILLYLSHLIQVVLRIICLAIFANWFTYYVLIVIGFHWIVGLVILIVYRFHMKAKTLGKSMISCSS----FLSALFFGYVGIFDFVNGNEGKTXXXXXXXXXXXXIENIFMLVLWIAKFPTTQIRYPIPFVCV 1383
            +DL+SDR+I  K+  I+L    + S+WI V          T +EV V+   L+ G YI  GI +   YW RW  ++     + +EENK+AWVC+RI L+L+G+  V RYIE+++V R++ DLEK++L  +V   KE  Q + + +   GS+I+  +L         QS    A  + N     E     VR  K RRQ++R E D A +AL +GV GAGP  I+  VL+ +R+    +M+ D    V+   I  V+WL A LTH+YP+ + QSE +F+RGV       + LLY +HLI + LR+  L +F   F + VL V+ FH+   L  L+V R          + I  SS     L    F YVG+F+F N     TR RYL++Y FYY+EN  M+  W   F   Q+ Y +P + V
Sbjct:   51 DDLISDRAIWRKVTCIILCLLFVFSAWIIVVLHVVHFTNQTVLEVSVTVVTLLIGQYIGTGIFDCYRYWIRWSTASKKSHSKQQEENKEAWVCMRITLALMGLAPVSRYIESLVVVRRMIDLEKRYLAEAVAFAKEVKQPSTLPS---GSLISGPSL------ATRQS--EAAASSKNAARFRELDAGLVRVYKVRRQFRRTEQDAALVALASGVLGAGPFVISQGVLFFRRVGLNFSMTNDAMVGVLGCTITGVIWLCAGLTHYYPAAYDQSEFDFDRGVGQVPARGLALLYSAHLIHITLRLGTLVLFTAQFYWIVLAVLAFHYFFVLFSLVVSRACTSTDYSNPAKIERSSISGNLLFDFMFAYVGLFEFANAYAKYTRTRYLLYYFFYYLENSAMIGAWYVHFTYPQVWYYLPSLLV 460
[Close]
BLAST of XK-related protein vs. Ensembl Medaka
Match: zgc:123035 (XK related 4 [Source:NCBI gene;Acc:101174456])

HSP 1 Score: 50.0618 bits (118), Expect = 9.408e-6
Identity = 39/136 (28.68%), Postives = 62/136 (45.59%), Query Frame = 1 
Query:  994 AIILLYLSHLIQVVLRIICLAIFANWFTYYVLIVIGFHWIVGLVILIVYRFHMKAKTLGKSMISCSSFLSALFF----GYVGIFDFVNGNEGKTXXXXXXXXXXXXIENIFMLVLW-IAKFPTTQIRYPIPFVCVI 1386
            A+I+ +  H   +  R+I  A+FA+ F  Y  I I  HW     I+  +  H +          C S    + F    G + IF + N  EG+TR R  ++Y    +EN  +  LW + + P T   + +P +CVI
Sbjct:  333 AVIIQFCWHFFTIAARVITFALFASVFQLYFGIFIVLHW----CIMTFWIVHCETDF-------CISKWEEIVFDMVVGIIYIFSWFNVKEGRTRCRLFIYYFVILVENAALSALWYLYRIPKTTDAFAVPALCVI 457
[Close]
BLAST of XK-related protein vs. Planmine SMEST
Match: SMESG000080414.1 (SMESG000080414.1)

HSP 1 Score: 1221.84 bits (3160), Expect = 0.000e+0
Identity = 687/708 (97.03%), Postives = 690/708 (97.46%), Query Frame = 1 
Query:  142 EDLVSDRSIPLKICMIVLNCFQIISSWIAVCFFFTSIQEWTPMEVGVSGGILIFGNYIVPGIANGIIYWKRWKRSTPGYRRRMEEENKQAWVCLRIALSLLGIPTVGRYIETIMVSRKLDDLEKKHLHASVNTHKEGSQLNPVGTSRLGSIINQKNLERMSKSGINQSVISGATQTYNINGMNENSQDKVRKARRQYKRCEHDXXXXXXXXXXXXXXXXXXXFAVLYLQRIERINMSVDQGSAVIVAAILNVLWLSATLTHFYPSRHVQSEAEFERGVSTSNIGAIILLYLSHLIQVVLRIICLAIFANWFTYYVLIVIGFHWIVGLVILIVYRFHMKAKTLGKSMISCSSFLSALFFGYVGIFDFVNGNEGKTXXXXXXXXXXXXIENIFMLVLWIAKFPTTQIRYPIPFVCVIXXXXXXXXXXXXXXXXXXXXXXXXXXIIGCCQRKHRKNSVKYVEEVREPVFGVPLSQSAVPLWQHHQPENTAPSSRISGTSNPSYKYGRLNPLDPRNTPSIMSIPSAKSPPSILSQSPGYPNQPIEKQKPVSSRKNPPVMEQKSRKENAKPPAKRDFXXXXXXXGEELPKFTPKPIRDSHSHPNLXXXXXXXXXXXXXQIKEPEVIKSKYKAEPVNITARSSHGSKSMDNISAMIPAMGPTKTTKPIGAPIRPISNHIQGVHKSHNNTGRPRNPHPQKRNPNSLQPSNIRKIR 2265
            EDLVSDRSIPLKICMIVLNCFQIISSWIAVCFFFTSIQEWTPMEVGVSGGILIFGNYIVPGIANGIIYWKRWKRSTPGYRRRMEEENKQAWVCLRIALSLLGIPTVGRYIETIMVSRKLDDLEKKHLHASVNTHKEGSQLNP+GTSRLGSIINQKNLERMSKSGINQSVISGATQTYNINGMNENSQDKVRKARRQYKRCEHDGAQMALLAGVAGAGPLAIAFAVLYLQRIERINMSVDQGSAVIVAAILNVLWLSATLTHFYPSRHVQSEAEFERGVST                +VLRIICLAIFANWFTYYVLIVIGFHWIVGLVILIVYRFHMKAKTLGKSMISCSSFLSALFFGYVGIFDFVNGNEGKTRLRYLVFYLFYYIENIFMLVLWIAKFPTTQIRYPIPFVCVILALFWLGFLFLQLYLYYFSYSPYGSSIIGCCQ KHRKNSVKYVEEVREPVFGVPLSQSAVPLWQHHQPENTAPSSRISGTSNPSYKYGRLNPLDPRNTPSIMSIPSAKSPPSILSQSPG PNQPIEKQKPVSSRKNPPVMEQKSRKENAKPPAKRDFSSDSSSSGEELPKFTPKPIRDSHSHPNLSGPISSNSSESYSQIKEPEVIKSKYKAEPVNITARSSHGSKSMDNISAMIPAMGPTKTTKPIGAPIRPISNH+QGVHKSHNNTGRPRNPHPQKRNPNSLQPSNIRKIR
Sbjct:   15 EDLVSDRSIPLKICMIVLNCFQIISSWIAVCFFFTSIQEWTPMEVGVSGGILIFGNYIVPGIANGIIYWKRWKRSTPGYRRRMEEENKQAWVCLRIALSLLGIPTVGRYIETIMVSRKLDDLEKKHLHASVNTHKEGSQLNPIGTSRLGSIINQKNLERMSKSGINQSVISGATQTYNINGMNENSQDKVRKARRQYKRCEHDGAQMALLAGVAGAGPLAIAFAVLYLQRIERINMSVDQGSAVIVAAILNVLWLSATLTHFYPSRHVQSEAEFERGVST----------------IVLRIICLAIFANWFTYYVLIVIGFHWIVGLVILIVYRFHMKAKTLGKSMISCSSFLSALFFGYVGIFDFVNGNEGKTRLRYLVFYLFYYIENIFMLVLWIAKFPTTQIRYPIPFVCVILALFWLGFLFLQLYLYYFSYSPYGSSIIGCCQGKHRKNSVKYVEEVREPVFGVPLSQSAVPLWQHHQPENTAPSSRISGTSNPSYKYGRLNPLDPRNTPSIMSIPSAKSPPSILSQSPGNPNQPIEKQKPVSSRKNPPVMEQKSRKENAKPPAKRDFSSDSSSSGEELPKFTPKPIRDSHSHPNLSGPISSNSSESYSQIKEPEVIKSKYKAEPVNITARSSHGSKSMDNISAMIPAMGPTKTTKPIGAPIRPISNHVQGVHKSHNNTGRPRNPHPQKRNPNSLQPSNIRKIR 706
The following BLAST results are available for this feature:
BLAST of XK-related protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of XK-related protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of XK-related protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of XK-related protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of XK-related protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of XK-related protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of XK-related protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of XK-related protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A5J4NJL54.844e-6336.43XK-related protein OS=Paragonimus westermani OX=34... [more]
A0A1S8WRM42.208e-5737.56XK-related protein (Fragment) OS=Opisthorchis vive... [more]
A0A075A9875.498e-5737.20XK-related protein OS=Opisthorchis viverrini OX=61... [more]
A0A4S2M8671.274e-5536.97XK-related protein OS=Opisthorchis felineus OX=147... [more]
G7YC275.511e-5537.05XK-related protein OS=Clonorchis sinensis OX=79923... [more]
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BLAST of XK-related protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of XK-related protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of XK-related protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of XK-related protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of XK-related protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 1
Match NameE-valueIdentityDescription
zgc:1230359.408e-628.68XK related 4 [Source:NCBI gene;Acc:101174456][more]
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BLAST of XK-related protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 1
Match NameE-valueIdentityDescription
SMESG000080414.10.000e+097.03SMESG000080414.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30018439 ID=SMED30018439|Name=XK-related protein|organism=Schmidtea mediterranea sexual|type=transcript|length=2446bp
CTGAATAAAGATGTAAATTAACAACTCTAATGAGATTTAAATACTGTACA
TAATATAAATGTCCTGTTTGTAATTTTATATAGTATTTAATTTATTGATA
TGGCATCAGCAGTATCTCAAAGTAGTGTTGCTACTGTTGTTGAAGATTTA
GTTTCAGACCGAAGCATCCCATTAAAAATATGTATGATTGTTCTTAATTG
TTTTCAAATAATTTCAAGTTGGATTGCTGTTTGTTTCTTTTTTACAAGTA
TTCAGGAGTGGACTCCTATGGAAGTTGGTGTGTCAGGGGGGATTCTTATT
TTTGGAAATTATATTGTTCCCGGAATAGCAAATGGAATTATTTACTGGAA
GAGGTGGAAACGATCAACACCAGGTTATCGTCGAAGGATGGAAGAAGAAA
ATAAACAAGCTTGGGTTTGTTTAAGAATAGCACTATCACTTTTGGGAATA
CCTACTGTTGGCAGATATATTGAAACAATCATGGTATCTCGTAAACTAGA
CGATTTAGAGAAAAAGCATCTTCACGCATCAGTAAATACACATAAAGAAG
GAAGTCAGTTAAATCCTGTTGGAACCAGTCGATTAGGTTCAATCATCAAC
CAAAAGAATCTTGAACGAATGTCGAAATCTGGAATTAACCAATCAGTTAT
TTCGGGTGCAACACAAACATATAATATTAATGGAATGAATGAAAATAGCC
AAGATAAAGTAAGAAAAGCAAGAAGGCAATACAAGCGATGTGAACATGAC
GGAGCACAAATGGCATTATTGGCAGGTGTAGCTGGTGCAGGTCCTTTAGC
CATAGCTTTCGCGGTTCTATATCTTCAACGAATAGAAAGAATTAACATGT
CAGTAGACCAAGGATCGGCTGTTATTGTAGCTGCAATATTGAATGTTTTG
TGGCTTAGTGCAACTTTGACTCATTTTTATCCATCGCGACATGTTCAGTC
TGAAGCAGAATTTGAGAGGGGAGTTTCGACAAGTAATATTGGGGCTATCA
TTCTTTTGTATTTATCACATCTTATTCAAGTAGTTTTAAGAATTATTTGT
CTGGCAATTTTTGCAAATTGGTTCACTTATTATGTTTTGATTGTTATAGG
GTTTCATTGGATAGTTGGGCTAGTTATTCTTATTGTGTATAGGTTTCATA
TGAAAGCTAAAACTCTTGGAAAATCTATGATTTCATGTTCTTCTTTTTTA
TCTGCACTGTTTTTTGGTTATGTTGGAATTTTCGATTTCGTTAATGGAAA
TGAGGGCAAAACTAGGTTGCGATATCTTGTTTTTTACTTATTTTATTACA
TTGAAAATATTTTTATGCTTGTACTTTGGATTGCAAAATTTCCAACTACA
CAAATTCGTTATCCTATTCCTTTTGTTTGTGTTATATTAGCTTTATTTTG
GCTGGGATTTCTATTTCTTCAGTTATACTTATACTATTTTAGTTATAGTC
CATATGGCTCTAGTATAATTGGATGTTGTCAAAGAAAACATAGGAAAAAT
TCTGTAAAGTATGTCGAGGAAGTAAGAGAGCCTGTGTTTGGAGTACCTTT
GTCTCAGTCAGCAGTTCCCCTATGGCAACATCACCAGCCTGAGAATACAG
CACCGAGTTCACGGATTTCCGGTACGAGCAATCCTAGTTATAAATATGGA
CGACTTAATCCATTAGACCCCAGAAATACTCCATCAATAATGTCTATACC
ATCTGCAAAGTCACCACCTAGTATTTTAAGCCAATCTCCAGGATACCCAA
ATCAACCAATTGAAAAACAAAAGCCTGTTTCTTCCCGGAAGAATCCTCCT
GTTATGGAACAAAAATCAAGAAAAGAAAATGCAAAACCTCCTGCTAAACG
TGATTTTTCAAGCGATTCTTCATCATCAGGCGAAGAACTTCCAAAGTTCA
CACCTAAGCCTATAAGAGACTCCCATAGTCATCCTAATCTATCTGGTCCA
ATATCATCAAATTCATCGGAATCATACAGCCAGATAAAAGAACCTGAAGT
TATTAAAAGTAAATACAAAGCAGAACCAGTTAATATAACAGCTCGTAGTT
CTCATGGGTCAAAATCTATGGATAACATTTCCGCAATGATTCCTGCGATG
GGACCTACCAAGACAACTAAACCTATTGGAGCACCAATAAGGCCAATTTC
CAATCATATTCAAGGTGTACATAAATCACACAATAACACGGGAAGACCAA
GAAATCCACATCCTCAAAAACGAAATCCAAATTCGCTTCAACCAAGTAAT
ATAAGAAAAATTCGGTAAAAATATTTTTTGGGATTTTCAACATAGATTTG
TTAGCTGTTATTTTGGTAAATTTCCTTATATCATTAAAAGGCTGTGAATG
TTTTGTGTGATGAAAATCTGGCATATCATGATTTTATAAAATTTTTGACG
TACATTGTTTTTTTTTTGATATTGTAATGTACTTAATAAATTAATG
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protein sequence of SMED30018439-orf-1

>SMED30018439-orf-1 ID=SMED30018439-orf-1|Name=SMED30018439-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=723bp
MASAVSQSSVATVVEDLVSDRSIPLKICMIVLNCFQIISSWIAVCFFFTS
IQEWTPMEVGVSGGILIFGNYIVPGIANGIIYWKRWKRSTPGYRRRMEEE
NKQAWVCLRIALSLLGIPTVGRYIETIMVSRKLDDLEKKHLHASVNTHKE
GSQLNPVGTSRLGSIINQKNLERMSKSGINQSVISGATQTYNINGMNENS
QDKVRKARRQYKRCEHDGAQMALLAGVAGAGPLAIAFAVLYLQRIERINM
SVDQGSAVIVAAILNVLWLSATLTHFYPSRHVQSEAEFERGVSTSNIGAI
ILLYLSHLIQVVLRIICLAIFANWFTYYVLIVIGFHWIVGLVILIVYRFH
MKAKTLGKSMISCSSFLSALFFGYVGIFDFVNGNEGKTRLRYLVFYLFYY
IENIFMLVLWIAKFPTTQIRYPIPFVCVILALFWLGFLFLQLYLYYFSYS
PYGSSIIGCCQRKHRKNSVKYVEEVREPVFGVPLSQSAVPLWQHHQPENT
APSSRISGTSNPSYKYGRLNPLDPRNTPSIMSIPSAKSPPSILSQSPGYP
NQPIEKQKPVSSRKNPPVMEQKSRKENAKPPAKRDFSSDSSSSGEELPKF
TPKPIRDSHSHPNLSGPISSNSSESYSQIKEPEVIKSKYKAEPVNITARS
SHGSKSMDNISAMIPAMGPTKTTKPIGAPIRPISNHIQGVHKSHNNTGRP
RNPHPQKRNPNSLQPSNIRKIR*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: cellular component
TermDefinition
GO:0016020membrane
GO:0016021integral component of membrane
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000016pharynx
PLANA:0000018Category 4 cell
PLANA:0000020protonephridia
PLANA:0000034epidermis
PLANA:0000099neuron
PLANA:0002032epidermal cell
Vocabulary: INTERPRO
TermDefinition
IPR018629XK-rel
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR018629XK-related proteinPFAMPF09815XK-relatedcoord: 13..97
e-value: 6.5E-13
score: 48.4
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 147..167
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 262..280
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 218..233
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 184..217
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 332..372
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 147..166
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 184..288
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 338..372
NoneNo IPR availablePANTHERPTHR16024FAMILY NOT NAMEDcoord: 12..151
NoneNo IPR availableTMHMMTMhelixcoord: 40..62
NoneNo IPR availableTMHMMTMhelixcoord: 75..97
NoneNo IPR availableTMHMMTMhelixcoord: 13..30