TAR DNA-binding protein 43

Overview
NameTAR DNA-binding protein 43
Smed IDSMED30018423
Length (bp)1901
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of TAR DNA-binding protein 43 (SMED30018423) t-SNE clustered cells

Violin plots show distribution of expression levels for TAR DNA-binding protein 43 (SMED30018423) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of TAR DNA-binding protein 43 (SMED30018423) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for TAR DNA-binding protein 43 (SMED30018423) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30018423

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 5

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
protonephridiaSMED30018423h1SMcG0015768 dd_Smed_v4_20304_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
nervous systemSMED30018423h1SMcG0015768 dd_Smed_v4_20304_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30018423h1SMcG0015768 dd_Smed_v4_20304_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymaSMED30018423h1SMcG0015768 dd_Smed_v4_20304_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
non-ciliated neuronSMED30018423h1SMcG0015768 dd_Smed_v4_20304_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of TAR DNA-binding protein 43 vs. Ensembl Human
Match: TARDBP (TAR DNA binding protein [Source:HGNC Symbol;Acc:HGNC:11571])

HSP 1 Score: 144.05 bits (362), Expect = 6.792e-38
Identity = 78/246 (31.71%), Postives = 139/246 (56.50%), Query Frame = 3
Query:   90 NKYVRVKGIDNLEIVELPLDLDNTLSFAVLSSQFPYSTGLKYRNSKNNQIRTVRRTDGKFFLSPDLNWDDFLFFCCCSQSKRKMLENPNEKSQIQKKPETLKSIFQKFPDTFDLIAIGLSYDTTENDLTDYLNRFGKLVYCKLKCDDVFGYSRGVAYFRFSGIKSQNLCLSATHVVDKTKIMIRIPNEKINIKE-RESSKLYVSNVCNTLTREDLRAYFHQFGHVIHVFLPPDKRNFAFVTFLHDK 824
            ++Y+RV   +N E +E+P + D T+  + +++QFP + GL+YRN  +  +R VR  +G    +PD  W + ++     +  ++ ++  +  S ++     +K   QK   T DLI +GL + TTE DL +Y + FG+++  ++K D   G+S+G  + RF+  ++Q   +S  H++D      ++PN K +  E   S K++V      +T ++LR +F Q+G V+ VF+P   R FAFVTF  D+
Sbjct:    2 SEYIRVTEDENDEPIEIPSEDDGTVLLSTVTAQFPGACGLRYRNPVSQCMRGVRLVEG-ILHAPDAGWGNLVYVVNYPKDNKRKMDETDASSAVK-----VKRAVQK---TSDLIVLGLPWKTTEQDLKEYFSTFGEVLMVQVKKDLKTGHSKGFGFVRFTEYETQVKVMSQRHMIDGRWCDCKLPNSKQSQDEPLRSRKVFVGRCTEDMTEDELREFFSQYGDVMDVFIPKPFRAFAFVTFADDQ 238          
BLAST of TAR DNA-binding protein 43 vs. Ensembl Human
Match: TARDBP (TAR DNA binding protein [Source:HGNC Symbol;Acc:HGNC:11571])

HSP 1 Score: 143.665 bits (361), Expect = 7.529e-38
Identity = 78/246 (31.71%), Postives = 139/246 (56.50%), Query Frame = 3
Query:   90 NKYVRVKGIDNLEIVELPLDLDNTLSFAVLSSQFPYSTGLKYRNSKNNQIRTVRRTDGKFFLSPDLNWDDFLFFCCCSQSKRKMLENPNEKSQIQKKPETLKSIFQKFPDTFDLIAIGLSYDTTENDLTDYLNRFGKLVYCKLKCDDVFGYSRGVAYFRFSGIKSQNLCLSATHVVDKTKIMIRIPNEKINIKE-RESSKLYVSNVCNTLTREDLRAYFHQFGHVIHVFLPPDKRNFAFVTFLHDK 824
            ++Y+RV   +N E +E+P + D T+  + +++QFP + GL+YRN  +  +R VR  +G    +PD  W + ++     +  ++ ++  +  S ++     +K   QK   T DLI +GL + TTE DL +Y + FG+++  ++K D   G+S+G  + RF+  ++Q   +S  H++D      ++PN K +  E   S K++V      +T ++LR +F Q+G V+ VF+P   R FAFVTF  D+
Sbjct:    2 SEYIRVTEDENDEPIEIPSEDDGTVLLSTVTAQFPGACGLRYRNPVSQCMRGVRLVEG-ILHAPDAGWGNLVYVVNYPKDNKRKMDETDASSAVK-----VKRAVQK---TSDLIVLGLPWKTTEQDLKEYFSTFGEVLMVQVKKDLKTGHSKGFGFVRFTEYETQVKVMSQRHMIDGRWCDCKLPNSKQSQDEPLRSRKVFVGRCTEDMTEDELREFFSQYGDVMDVFIPKPFRAFAFVTFADDQ 238          
BLAST of TAR DNA-binding protein 43 vs. Ensembl Human
Match: TARDBP (TAR DNA binding protein [Source:HGNC Symbol;Acc:HGNC:11571])

HSP 1 Score: 143.665 bits (361), Expect = 7.529e-38
Identity = 78/246 (31.71%), Postives = 139/246 (56.50%), Query Frame = 3
Query:   90 NKYVRVKGIDNLEIVELPLDLDNTLSFAVLSSQFPYSTGLKYRNSKNNQIRTVRRTDGKFFLSPDLNWDDFLFFCCCSQSKRKMLENPNEKSQIQKKPETLKSIFQKFPDTFDLIAIGLSYDTTENDLTDYLNRFGKLVYCKLKCDDVFGYSRGVAYFRFSGIKSQNLCLSATHVVDKTKIMIRIPNEKINIKE-RESSKLYVSNVCNTLTREDLRAYFHQFGHVIHVFLPPDKRNFAFVTFLHDK 824
            ++Y+RV   +N E +E+P + D T+  + +++QFP + GL+YRN  +  +R VR  +G    +PD  W + ++     +  ++ ++  +  S ++     +K   QK   T DLI +GL + TTE DL +Y + FG+++  ++K D   G+S+G  + RF+  ++Q   +S  H++D      ++PN K +  E   S K++V      +T ++LR +F Q+G V+ VF+P   R FAFVTF  D+
Sbjct:    2 SEYIRVTEDENDEPIEIPSEDDGTVLLSTVTAQFPGACGLRYRNPVSQCMRGVRLVEG-ILHAPDAGWGNLVYVVNYPKDNKRKMDETDASSAVK-----VKRAVQK---TSDLIVLGLPWKTTEQDLKEYFSTFGEVLMVQVKKDLKTGHSKGFGFVRFTEYETQVKVMSQRHMIDGRWCDCKLPNSKQSQDEPLRSRKVFVGRCTEDMTEDELREFFSQYGDVMDVFIPKPFRAFAFVTFADDQ 238          
BLAST of TAR DNA-binding protein 43 vs. Ensembl Human
Match: AL109811.3 (novel protein)

HSP 1 Score: 143.665 bits (361), Expect = 7.529e-38
Identity = 78/246 (31.71%), Postives = 139/246 (56.50%), Query Frame = 3
Query:   90 NKYVRVKGIDNLEIVELPLDLDNTLSFAVLSSQFPYSTGLKYRNSKNNQIRTVRRTDGKFFLSPDLNWDDFLFFCCCSQSKRKMLENPNEKSQIQKKPETLKSIFQKFPDTFDLIAIGLSYDTTENDLTDYLNRFGKLVYCKLKCDDVFGYSRGVAYFRFSGIKSQNLCLSATHVVDKTKIMIRIPNEKINIKE-RESSKLYVSNVCNTLTREDLRAYFHQFGHVIHVFLPPDKRNFAFVTFLHDK 824
            ++Y+RV   +N E +E+P + D T+  + +++QFP + GL+YRN  +  +R VR  +G    +PD  W + ++     +  ++ ++  +  S ++     +K   QK   T DLI +GL + TTE DL +Y + FG+++  ++K D   G+S+G  + RF+  ++Q   +S  H++D      ++PN K +  E   S K++V      +T ++LR +F Q+G V+ VF+P   R FAFVTF  D+
Sbjct:    2 SEYIRVTEDENDEPIEIPSEDDGTVLLSTVTAQFPGACGLRYRNPVSQCMRGVRLVEG-ILHAPDAGWGNLVYVVNYPKDNKRKMDETDASSAVK-----VKRAVQK---TSDLIVLGLPWKTTEQDLKEYFSTFGEVLMVQVKKDLKTGHSKGFGFVRFTEYETQVKVMSQRHMIDGRWCDCKLPNSKQSQDEPLRSRKVFVGRCTEDMTEDELREFFSQYGDVMDVFIPKPFRAFAFVTFADDQ 238          
BLAST of TAR DNA-binding protein 43 vs. Ensembl Human
Match: TARDBP (TAR DNA binding protein [Source:HGNC Symbol;Acc:HGNC:11571])

HSP 1 Score: 142.895 bits (359), Expect = 8.403e-38
Identity = 78/246 (31.71%), Postives = 139/246 (56.50%), Query Frame = 3
Query:   90 NKYVRVKGIDNLEIVELPLDLDNTLSFAVLSSQFPYSTGLKYRNSKNNQIRTVRRTDGKFFLSPDLNWDDFLFFCCCSQSKRKMLENPNEKSQIQKKPETLKSIFQKFPDTFDLIAIGLSYDTTENDLTDYLNRFGKLVYCKLKCDDVFGYSRGVAYFRFSGIKSQNLCLSATHVVDKTKIMIRIPNEKINIKE-RESSKLYVSNVCNTLTREDLRAYFHQFGHVIHVFLPPDKRNFAFVTFLHDK 824
            ++Y+RV   +N E +E+P + D T+  + +++QFP + GL+YRN  +  +R VR  +G    +PD  W + ++     +  ++ ++  +  S ++     +K   QK   T DLI +GL + TTE DL +Y + FG+++  ++K D   G+S+G  + RF+  ++Q   +S  H++D      ++PN K +  E   S K++V      +T ++LR +F Q+G V+ VF+P   R FAFVTF  D+
Sbjct:    2 SEYIRVTEDENDEPIEIPSEDDGTVLLSTVTAQFPGACGLRYRNPVSQCMRGVRLVEG-ILHAPDAGWGNLVYVVNYPKDNKRKMDETDASSAVK-----VKRAVQK---TSDLIVLGLPWKTTEQDLKEYFSTFGEVLMVQVKKDLKTGHSKGFGFVRFTEYETQVKVMSQRHMIDGRWCDCKLPNSKQSQDEPLRSRKVFVGRCTEDMTEDELREFFSQYGDVMDVFIPKPFRAFAFVTFADDQ 238          
BLAST of TAR DNA-binding protein 43 vs. Ensembl Celegans
Match: tdp-1 (Tar DNA-binding protein homolog 1 [Source:UniProtKB/Swiss-Prot;Acc:D0VWM8])

HSP 1 Score: 94.7449 bits (234), Expect = 1.610e-20
Identity = 72/291 (24.74%), Postives = 132/291 (45.36%), Query Frame = 3
Query:   93 KYVRVKGIDNLEIVELPLDLDNTLSFAVLSSQFPYSTGLKYRNSKNNQIRTVR-RTDGKFFLSPDLNWDDFLFFCCCS-QSKR-KMLENPNEKSQIQKK---------------PETLKSIFQKFPDTFDLIAIGLSYDTTENDLTDYLNRFGKLVYCKLKCDDVFGYSRGVAYFRFSGIKSQNLCLS-ATHVVDKTKIMIRIPNEKINIKERESSKLYVSNVCNTLTREDLRAYFH-------QFGHVIHVFLPPDKRNFAFVTFLHDKSIELVMKEGQTHCFNGARVNV 887
            +++ V+  +  E +ELP  +D  +    L + FP +TGLKY+N K    R V+    G   ++P   W++  FF   + QS+R + L + +  S  ++K                   K   ++     DLI +G+ + TT+     Y    G +V+C++K     G S+G  + R S +  QN  L+   H++D  +  +++P+ +        S+++V  + + +    LR  F        +   V  VF+P   R FAFVT    ++ E ++ +G +   NG  V +
Sbjct:   46 EFITVQDPNGDEPIELPT-VDGVVLMTTLQASFPGATGLKYKNPKTGANRAVQVDPSGLKLIAPADGWENKTFFVIVAPQSERVRALSSADATSAKRRKVGSSDDSDSDDGRDGRSGRKRAVERDSQPVDLIVLGVDFKTTDECFQKYFEDIGTVVFCEIKRKS-DGNSKGFGFVRMSSVGEQNKVLAIPQHMIDGRRCDVKVPDGRDKQGRPSISRIFVGRLTDKVDEHQLRKVFGDEAKSYIETAVVTDVFIPKPFRGFAFVTLSSAEAAERIVSKG-SLTVNGLSVGL 333          
BLAST of TAR DNA-binding protein 43 vs. Ensembl Celegans
Match: tdp-1 (Tar DNA-binding protein homolog 1 [Source:UniProtKB/Swiss-Prot;Acc:D0VWM8])

HSP 1 Score: 92.8189 bits (229), Expect = 6.374e-20
Identity = 72/295 (24.41%), Postives = 138/295 (46.78%), Query Frame = 3
Query:   93 KYVRVKGIDNLEIVELPLDLDNTLSFAVLSSQFPYSTGLKYRNSKNNQIRTVR-RTDGKFFLSPDLNWDDFLFFCCCS-QSKR-KMLENPNEKSQIQKK---------------PETLKSIFQKFPDTFDLIAIGLSYDTTENDLTDYLNRFGKLVYCKLKCDDVFGYSRGVAYFRFSGIKSQNLCLS-ATHVVDKTKIMIRIPNEKINIKERES----SKLYVSNVCNTLTREDLRAYFH-------QFGHVIHVFLPPDKRNFAFVTFLHDKSIELVMKEGQTHCFNGARVNV 887
            +++ V+  +  E +ELP  +D  +    L + FP +TGLKY+N K    R V+    G   ++P   W++  FF   + QS+R + L + +  S  ++K                   K   ++     DLI +G+ + TT+     Y    G +V+C++K     G S+G  + R S +  QN  L+   H++D  +  +++P+ + ++++++     S+++V  + + +    LR  F        +   V  VF+P   R FAFVT    ++ E ++ +G +   NG  V +
Sbjct:   46 EFITVQDPNGDEPIELPT-VDGVVLMTTLQASFPGATGLKYKNPKTGANRAVQVDPSGLKLIAPADGWENKTFFVIVAPQSERVRALSSADATSAKRRKVGSSDDSDSDDGRDGRSGRKRAVERDSQPVDLIVLGVDFKTTDECFQKYFEDIGTVVFCEIKRKS-DGNSKGFGFVRMSSVGEQNKVLAIPQHMIDGRRCDVKVPDGR-SLQDKQGRPSISRIFVGRLTDKVDEHQLRKVFGDEAKSYIETAVVTDVFIPKPFRGFAFVTLSSAEAAERIVSKG-SLTVNGLSVGL 336          
BLAST of TAR DNA-binding protein 43 vs. Ensembl Celegans
Match: sqd-1 (Homologous to Drosophila SQD (Squid) protein [Source:UniProtKB/TrEMBL;Acc:Q8MXR6])

HSP 1 Score: 72.7886 bits (177), Expect = 9.587e-14
Identity = 42/140 (30.00%), Postives = 72/140 (51.43%), Query Frame = 3
Query:  429 LIAIGLSYDTTENDLTDYLNRFGKLVYCKLKCDDVFGYSRGVAYFRFSGIKSQNLCLSATHVVDKTKIMIRIPNEKINIKERESSKLYVSNVCNTLTREDLRAYFHQFGHVIHVFLPPDK-----RNFAFVTFLHDKSIE 833
            +   G+S +    DL+ +  ++G++   ++K D   G SRG A+  F+  +   L L+A     K K +   P      K RE+ K++V  + +  + +DLR++F QFG V  +  P DK     RNFAF+ F  ++S +
Sbjct:   31 IFVGGISPEVNNEDLSSHFTQYGEVAQAQVKYDRTNGRSRGFAFVEFTTGEGCKLALAAREQTIKGKSVEVKP-----AKSRENKKVFVGGLPSDYSEQDLRSHFEQFGKVDDIEWPFDKQTKARRNFAFIVFEEEESAD 165          
BLAST of TAR DNA-binding protein 43 vs. Ensembl Celegans
Match: sqd-1 (Homologous to Drosophila SQD (Squid) protein [Source:UniProtKB/TrEMBL;Acc:Q8MXR6])

HSP 1 Score: 72.7886 bits (177), Expect = 9.587e-14
Identity = 42/140 (30.00%), Postives = 72/140 (51.43%), Query Frame = 3
Query:  429 LIAIGLSYDTTENDLTDYLNRFGKLVYCKLKCDDVFGYSRGVAYFRFSGIKSQNLCLSATHVVDKTKIMIRIPNEKINIKERESSKLYVSNVCNTLTREDLRAYFHQFGHVIHVFLPPDK-----RNFAFVTFLHDKSIE 833
            +   G+S +    DL+ +  ++G++   ++K D   G SRG A+  F+  +   L L+A     K K +   P      K RE+ K++V  + +  + +DLR++F QFG V  +  P DK     RNFAF+ F  ++S +
Sbjct:   31 IFVGGISPEVNNEDLSSHFTQYGEVAQAQVKYDRTNGRSRGFAFVEFTTGEGCKLALAAREQTIKGKSVEVKP-----AKSRENKKVFVGGLPSDYSEQDLRSHFEQFGKVDDIEWPFDKQTKARRNFAFIVFEEEESAD 165          
BLAST of TAR DNA-binding protein 43 vs. Ensembl Celegans
Match: sqd-1 (Homologous to Drosophila SQD (Squid) protein [Source:UniProtKB/TrEMBL;Acc:Q8MXR6])

HSP 1 Score: 72.7886 bits (177), Expect = 9.587e-14
Identity = 42/140 (30.00%), Postives = 72/140 (51.43%), Query Frame = 3
Query:  429 LIAIGLSYDTTENDLTDYLNRFGKLVYCKLKCDDVFGYSRGVAYFRFSGIKSQNLCLSATHVVDKTKIMIRIPNEKINIKERESSKLYVSNVCNTLTREDLRAYFHQFGHVIHVFLPPDK-----RNFAFVTFLHDKSIE 833
            +   G+S +    DL+ +  ++G++   ++K D   G SRG A+  F+  +   L L+A     K K +   P      K RE+ K++V  + +  + +DLR++F QFG V  +  P DK     RNFAF+ F  ++S +
Sbjct:   31 IFVGGISPEVNNEDLSSHFTQYGEVAQAQVKYDRTNGRSRGFAFVEFTTGEGCKLALAAREQTIKGKSVEVKP-----AKSRENKKVFVGGLPSDYSEQDLRSHFEQFGKVDDIEWPFDKQTKARRNFAFIVFEEEESAD 165          
BLAST of TAR DNA-binding protein 43 vs. Ensembl Fly
Match: CG7804 (gene:FBgn0036496 transcript:FBtr0332815)

HSP 1 Score: 155.221 bits (391), Expect = 4.924e-42
Identity = 89/273 (32.60%), Postives = 141/273 (51.65%), Query Frame = 3
Query:   96 YVRVKGIDNLEIVELPLDLDNTLSFAVLSSQFPYSTGLKYRNSKNNQIRTVRRTDGKFF-LSPDLNWDDFLFFCCCSQSKRKMLENPNEKSQIQKKPETLKSIFQKFPDTFDLIAIGLSYDTTENDLTDYLNRFGKLVYCKLKCDDVFGYSRGVAYFRFSGIKSQNLCLSATHVVDKTKIMIRIPNEKINIKERESSKLYVSNVCNTLTREDLRAYFHQFGHVIHVFLPPDKRNFAFVTFLHDKSIELVMKEGQTHCFNGARVNVYRVMEKDL 911
            +V V   +  E +ELP + D TL  + L +QFP S+GL+YRN     +R VR  +G+ +  S +  W ++ +FC   +  ++  E+  E S  + K        +     FDLI +GLSY+TTE DL +Y   +G +V  ++K D   G+S+G  + RF     Q   LS  H +D     +++P  +  +  +E  K++V      +  +DLR YF +FG VI VF+P   R F+FVTFL      +V   G+ H   G  V+V    +K++
Sbjct:    3 FVHVSEKEGDEPIELPAEEDGTLLLSTLQAQFPESSGLQYRNVDTKAVRGVRSNEGRLYSPSEETGWGEYHYFCVFPKKNKRQSEDNLENSTAKTKRT------EAHLRCFDLIVLGLSYNTTEQDLREYFETYGDVVKAEIKKDTRSGHSKGFGFVRFGSYDVQMHVLSKRHSIDGRWCEVKVPASR-GMGNQEPGKVFVGRCTEDIEADDLREYFSKFGEVIDVFIPKPFRAFSFVTFLDPYVPRVVC--GEKHIIKGVSVHVSTADKKNV 266          
BLAST of TAR DNA-binding protein 43 vs. Ensembl Fly
Match: CG7804 (gene:FBgn0036496 transcript:FBtr0075617)

HSP 1 Score: 155.221 bits (391), Expect = 4.924e-42
Identity = 89/273 (32.60%), Postives = 141/273 (51.65%), Query Frame = 3
Query:   96 YVRVKGIDNLEIVELPLDLDNTLSFAVLSSQFPYSTGLKYRNSKNNQIRTVRRTDGKFF-LSPDLNWDDFLFFCCCSQSKRKMLENPNEKSQIQKKPETLKSIFQKFPDTFDLIAIGLSYDTTENDLTDYLNRFGKLVYCKLKCDDVFGYSRGVAYFRFSGIKSQNLCLSATHVVDKTKIMIRIPNEKINIKERESSKLYVSNVCNTLTREDLRAYFHQFGHVIHVFLPPDKRNFAFVTFLHDKSIELVMKEGQTHCFNGARVNVYRVMEKDL 911
            +V V   +  E +ELP + D TL  + L +QFP S+GL+YRN     +R VR  +G+ +  S +  W ++ +FC   +  ++  E+  E S  + K        +     FDLI +GLSY+TTE DL +Y   +G +V  ++K D   G+S+G  + RF     Q   LS  H +D     +++P  +  +  +E  K++V      +  +DLR YF +FG VI VF+P   R F+FVTFL      +V   G+ H   G  V+V    +K++
Sbjct:    3 FVHVSEKEGDEPIELPAEEDGTLLLSTLQAQFPESSGLQYRNVDTKAVRGVRSNEGRLYSPSEETGWGEYHYFCVFPKKNKRQSEDNLENSTAKTKRT------EAHLRCFDLIVLGLSYNTTEQDLREYFETYGDVVKAEIKKDTRSGHSKGFGFVRFGSYDVQMHVLSKRHSIDGRWCEVKVPASR-GMGNQEPGKVFVGRCTEDIEADDLREYFSKFGEVIDVFIPKPFRAFSFVTFLDPYVPRVVC--GEKHIIKGVSVHVSTADKKNV 266          
BLAST of TAR DNA-binding protein 43 vs. Ensembl Fly
Match: TBPH (gene:FBgn0025790 transcript:FBtr0089626)

HSP 1 Score: 145.591 bits (366), Expect = 2.004e-38
Identity = 88/273 (32.23%), Postives = 139/273 (50.92%), Query Frame = 3
Query:   96 YVRVKGIDNLEIVELPLDLDNTLSFAVLSSQFPYSTGLKYRNSKNNQIRTVRRTDGKFFL-SPDLNWDDFLFFCC-CSQSKRKMLENPNEKSQIQKKPET-LKSIFQKFPDTFDLIAIGLSYDTTENDLTDYLNRFGKLVYCKLKCDDVFGYSRGVAYFRFSGIKSQNLCLSATHVVDKTKIMIRIPNEKINIKERESSKLYVSNVCNTLTREDLRAYFHQFGHVIHVFLPPDKRNFAFVTFLHDKSIELVMKEGQTHCFNGARVNVYRVMEK 905
            +V+V   +  E +ELP + D TL  + L +QFP S GLKYRN     +R VR  +G+ F  S +  W ++ +FC    ++KRK  +N    +   K+ ET L+          DLI +GL + TTE  L +Y   +G+++  ++K D   G S+G  + RF    +Q   L+  H++D     +++PN K  +  +   K++V      +  +DLR YF +FG V  VF+P   R F+FVTFL     + +   G+ H   G  V+V     K
Sbjct:    3 FVQVSEEEGDEPIELPAEEDGTLLLSTLQAQFPGSCGLKYRNLDTKAVRGVRSNEGRLFPPSVESGWGEYAYFCVFPKENKRKSDDNLENSTAKTKRIETRLRCT--------DLIVLGLPWKTTEESLREYFETYGEVLMAQIKKDTKSGQSKGFGFVRFGSYDAQMRVLTNRHLIDGRWCEVKVPNSK-GMGHQVPCKVFVGRCTEDINSDDLREYFSKFGEVTDVFIPRPFRAFSFVTFLDPDVAQSLC--GEDHIIKGVSVHVSNAAPK 264          
BLAST of TAR DNA-binding protein 43 vs. Ensembl Fly
Match: TBPH (gene:FBgn0025790 transcript:FBtr0089625)

HSP 1 Score: 145.976 bits (367), Expect = 5.042e-37
Identity = 88/273 (32.23%), Postives = 139/273 (50.92%), Query Frame = 3
Query:   96 YVRVKGIDNLEIVELPLDLDNTLSFAVLSSQFPYSTGLKYRNSKNNQIRTVRRTDGKFFL-SPDLNWDDFLFFCC-CSQSKRKMLENPNEKSQIQKKPET-LKSIFQKFPDTFDLIAIGLSYDTTENDLTDYLNRFGKLVYCKLKCDDVFGYSRGVAYFRFSGIKSQNLCLSATHVVDKTKIMIRIPNEKINIKERESSKLYVSNVCNTLTREDLRAYFHQFGHVIHVFLPPDKRNFAFVTFLHDKSIELVMKEGQTHCFNGARVNVYRVMEK 905
            +V+V   +  E +ELP + D TL  + L +QFP S GLKYRN     +R VR  +G+ F  S +  W ++ +FC    ++KRK  +N    +   K+ ET L+          DLI +GL + TTE  L +Y   +G+++  ++K D   G S+G  + RF    +Q   L+  H++D     +++PN K  +  +   K++V      +  +DLR YF +FG V  VF+P   R F+FVTFL     + +   G+ H   G  V+V     K
Sbjct:    3 FVQVSEEEGDEPIELPAEEDGTLLLSTLQAQFPGSCGLKYRNLDTKAVRGVRSNEGRLFPPSVESGWGEYAYFCVFPKENKRKSDDNLENSTAKTKRIETRLRCT--------DLIVLGLPWKTTEESLREYFETYGEVLMAQIKKDTKSGQSKGFGFVRFGSYDAQMRVLTNRHLIDGRWCEVKVPNSK-GMGHQVPCKVFVGRCTEDINSDDLREYFSKFGEVTDVFIPRPFRAFSFVTFLDPDVAQSLC--GEDHIIKGVSVHVSNAAPK 264          
BLAST of TAR DNA-binding protein 43 vs. Ensembl Fly
Match: TBPH (gene:FBgn0025790 transcript:FBtr0089624)

HSP 1 Score: 145.976 bits (367), Expect = 5.042e-37
Identity = 88/273 (32.23%), Postives = 139/273 (50.92%), Query Frame = 3
Query:   96 YVRVKGIDNLEIVELPLDLDNTLSFAVLSSQFPYSTGLKYRNSKNNQIRTVRRTDGKFFL-SPDLNWDDFLFFCC-CSQSKRKMLENPNEKSQIQKKPET-LKSIFQKFPDTFDLIAIGLSYDTTENDLTDYLNRFGKLVYCKLKCDDVFGYSRGVAYFRFSGIKSQNLCLSATHVVDKTKIMIRIPNEKINIKERESSKLYVSNVCNTLTREDLRAYFHQFGHVIHVFLPPDKRNFAFVTFLHDKSIELVMKEGQTHCFNGARVNVYRVMEK 905
            +V+V   +  E +ELP + D TL  + L +QFP S GLKYRN     +R VR  +G+ F  S +  W ++ +FC    ++KRK  +N    +   K+ ET L+          DLI +GL + TTE  L +Y   +G+++  ++K D   G S+G  + RF    +Q   L+  H++D     +++PN K  +  +   K++V      +  +DLR YF +FG V  VF+P   R F+FVTFL     + +   G+ H   G  V+V     K
Sbjct:    3 FVQVSEEEGDEPIELPAEEDGTLLLSTLQAQFPGSCGLKYRNLDTKAVRGVRSNEGRLFPPSVESGWGEYAYFCVFPKENKRKSDDNLENSTAKTKRIETRLRCT--------DLIVLGLPWKTTEESLREYFETYGEVLMAQIKKDTKSGQSKGFGFVRFGSYDAQMRVLTNRHLIDGRWCEVKVPNSK-GMGHQVPCKVFVGRCTEDINSDDLREYFSKFGEVTDVFIPRPFRAFSFVTFLDPDVAQSLC--GEDHIIKGVSVHVSNAAPK 264          
BLAST of TAR DNA-binding protein 43 vs. Ensembl Zebrafish
Match: tardbpl (TAR DNA binding protein, like [Source:ZFIN;Acc:ZDB-GENE-031030-1])

HSP 1 Score: 142.51 bits (358), Expect = 1.484e-37
Identity = 81/266 (30.45%), Postives = 141/266 (53.01%), Query Frame = 3
Query:   96 YVRVKGIDNLEIVELPLDLDNTLSFAVLSSQFPYSTGLKYRNSKNNQIRTVRRTDGKFFLSPDLNWDDFLFFCCCSQSKRKMLENPNEKSQIQKKPETLKSIFQKFPDTFDLIAIGLSYDTTENDLTDYLNRFGKLVYCKLKCDDVFGYSRGVAYFRFSGIKSQNLCLSATHVVDKTKIMIRIPNEKINIKE-RESSKLYVSNVCNTLTREDLRAYFHQFGHVIHVFLPPDKRNFAFVTFLHDKSIE------LVMKEGQTHCFNG 872
            Y+RV   +N E +E+P + D T+  + +++QFP + GL+YR+  +  +R VR  +G    +P+ +W + ++     +  ++ ++  +  S ++     +K   QK   T DLI +GL + TTE DL DY   FG+++  ++K D   G S+G  + RF+  ++Q   +S  H++D      ++PN K    E   S K++V      +T ++LR +F Q+G V  VF+P   R FAFVTF  D+  +      L++K    H  N 
Sbjct:    5 YIRVAEDENEEPMEIPSEEDGTVLLSTVAAQFPGACGLRYRSPVSQCMRGVRLVEG-VLHAPEADWGNLVYVVNYPKDNKRKMDEMDAASAVK-----IKRGIQK---TSDLIVLGLPWKTTEQDLKDYFGTFGEVIMVQVKRDAKSGNSKGFGFVRFTDYETQIKVMSQRHMIDGRWCDCKLPNSKAGPDEPMRSRKVFVGRCTEDMTADELRQFFMQYGEVTDVFIPKPFRAFAFVTFADDQVAQSLCGEDLIIKGTSVHISNA 261          
BLAST of TAR DNA-binding protein 43 vs. Ensembl Zebrafish
Match: tardbpl (TAR DNA binding protein, like [Source:ZFIN;Acc:ZDB-GENE-031030-1])

HSP 1 Score: 142.51 bits (358), Expect = 1.484e-37
Identity = 81/266 (30.45%), Postives = 141/266 (53.01%), Query Frame = 3
Query:   96 YVRVKGIDNLEIVELPLDLDNTLSFAVLSSQFPYSTGLKYRNSKNNQIRTVRRTDGKFFLSPDLNWDDFLFFCCCSQSKRKMLENPNEKSQIQKKPETLKSIFQKFPDTFDLIAIGLSYDTTENDLTDYLNRFGKLVYCKLKCDDVFGYSRGVAYFRFSGIKSQNLCLSATHVVDKTKIMIRIPNEKINIKE-RESSKLYVSNVCNTLTREDLRAYFHQFGHVIHVFLPPDKRNFAFVTFLHDKSIE------LVMKEGQTHCFNG 872
            Y+RV   +N E +E+P + D T+  + +++QFP + GL+YR+  +  +R VR  +G    +P+ +W + ++     +  ++ ++  +  S ++     +K   QK   T DLI +GL + TTE DL DY   FG+++  ++K D   G S+G  + RF+  ++Q   +S  H++D      ++PN K    E   S K++V      +T ++LR +F Q+G V  VF+P   R FAFVTF  D+  +      L++K    H  N 
Sbjct:    5 YIRVAEDENEEPMEIPSEEDGTVLLSTVAAQFPGACGLRYRSPVSQCMRGVRLVEG-VLHAPEADWGNLVYVVNYPKDNKRKMDEMDAASAVK-----IKRGIQK---TSDLIVLGLPWKTTEQDLKDYFGTFGEVIMVQVKRDAKSGNSKGFGFVRFTDYETQIKVMSQRHMIDGRWCDCKLPNSKAGPDEPMRSRKVFVGRCTEDMTADELRQFFMQYGEVTDVFIPKPFRAFAFVTFADDQVAQSLCGEDLIIKGTSVHISNA 261          
BLAST of TAR DNA-binding protein 43 vs. Ensembl Zebrafish
Match: tardbpl (TAR DNA binding protein, like [Source:ZFIN;Acc:ZDB-GENE-031030-1])

HSP 1 Score: 142.51 bits (358), Expect = 1.484e-37
Identity = 81/266 (30.45%), Postives = 141/266 (53.01%), Query Frame = 3
Query:   96 YVRVKGIDNLEIVELPLDLDNTLSFAVLSSQFPYSTGLKYRNSKNNQIRTVRRTDGKFFLSPDLNWDDFLFFCCCSQSKRKMLENPNEKSQIQKKPETLKSIFQKFPDTFDLIAIGLSYDTTENDLTDYLNRFGKLVYCKLKCDDVFGYSRGVAYFRFSGIKSQNLCLSATHVVDKTKIMIRIPNEKINIKE-RESSKLYVSNVCNTLTREDLRAYFHQFGHVIHVFLPPDKRNFAFVTFLHDKSIE------LVMKEGQTHCFNG 872
            Y+RV   +N E +E+P + D T+  + +++QFP + GL+YR+  +  +R VR  +G    +P+ +W + ++     +  ++ ++  +  S ++     +K   QK   T DLI +GL + TTE DL DY   FG+++  ++K D   G S+G  + RF+  ++Q   +S  H++D      ++PN K    E   S K++V      +T ++LR +F Q+G V  VF+P   R FAFVTF  D+  +      L++K    H  N 
Sbjct:    5 YIRVAEDENEEPMEIPSEEDGTVLLSTVAAQFPGACGLRYRSPVSQCMRGVRLVEG-VLHAPEADWGNLVYVVNYPKDNKRKMDEMDAASAVK-----IKRGIQK---TSDLIVLGLPWKTTEQDLKDYFGTFGEVIMVQVKRDAKSGNSKGFGFVRFTDYETQIKVMSQRHMIDGRWCDCKLPNSKAGPDEPMRSRKVFVGRCTEDMTADELRQFFMQYGEVTDVFIPKPFRAFAFVTFADDQVAQSLCGEDLIIKGTSVHISNA 261          
BLAST of TAR DNA-binding protein 43 vs. Ensembl Zebrafish
Match: tardbpl (TAR DNA binding protein, like [Source:ZFIN;Acc:ZDB-GENE-031030-1])

HSP 1 Score: 139.428 bits (350), Expect = 1.924e-36
Identity = 80/271 (29.52%), Postives = 143/271 (52.77%), Query Frame = 3
Query:   96 YVRVKGIDNLEIVELPLDLDNTLSFAVLSSQFPYSTGLKYRNSKNNQIRTVRRTDGKFFLSPDLNWDDFLFFCCCSQSKRKMLENPNEKSQIQKKPETLKSIFQKFPDTFDLIAIGLSYDTTENDLTDYLNRFGKLVYCKLKCDDVFGYSRGVAYFRFSGIKSQNLCLSATHVVDKTKIMIRIPNEKINIKER------ESSKLYVSNVCNTLTREDLRAYFHQFGHVIHVFLPPDKRNFAFVTFLHDKSIE------LVMKEGQTHCFNG 872
            Y+RV   +N E +E+P + D T+  + +++QFP + GL+YR+  +  +R VR  +G    +P+ +W + ++     +  ++ ++  +  S ++     +K   QK   T DLI +GL + TTE DL DY   FG+++  ++K D   G S+G  + RF+  ++Q   +S  H++D      ++PN K  +++        S K++V      +T ++LR +F Q+G V  VF+P   R FAFVTF  D+  +      L++K    H  N 
Sbjct:    5 YIRVAEDENEEPMEIPSEEDGTVLLSTVAAQFPGACGLRYRSPVSQCMRGVRLVEG-VLHAPEADWGNLVYVVNYPKDNKRKMDEMDAASAVK-----IKRGIQK---TSDLIVLGLPWKTTEQDLKDYFGTFGEVIMVQVKRDAKSGNSKGFGFVRFTDYETQIKVMSQRHMIDGRWCDCKLPNSKYFLEQAGPDEPMRSRKVFVGRCTEDMTADELRQFFMQYGEVTDVFIPKPFRAFAFVTFADDQVAQSLCGEDLIIKGTSVHISNA 266          
BLAST of TAR DNA-binding protein 43 vs. Ensembl Zebrafish
Match: tardbpl (TAR DNA binding protein, like [Source:ZFIN;Acc:ZDB-GENE-031030-1])

HSP 1 Score: 139.428 bits (350), Expect = 1.924e-36
Identity = 80/271 (29.52%), Postives = 143/271 (52.77%), Query Frame = 3
Query:   96 YVRVKGIDNLEIVELPLDLDNTLSFAVLSSQFPYSTGLKYRNSKNNQIRTVRRTDGKFFLSPDLNWDDFLFFCCCSQSKRKMLENPNEKSQIQKKPETLKSIFQKFPDTFDLIAIGLSYDTTENDLTDYLNRFGKLVYCKLKCDDVFGYSRGVAYFRFSGIKSQNLCLSATHVVDKTKIMIRIPNEKINIKER------ESSKLYVSNVCNTLTREDLRAYFHQFGHVIHVFLPPDKRNFAFVTFLHDKSIE------LVMKEGQTHCFNG 872
            Y+RV   +N E +E+P + D T+  + +++QFP + GL+YR+  +  +R VR  +G    +P+ +W + ++     +  ++ ++  +  S ++     +K   QK   T DLI +GL + TTE DL DY   FG+++  ++K D   G S+G  + RF+  ++Q   +S  H++D      ++PN K  +++        S K++V      +T ++LR +F Q+G V  VF+P   R FAFVTF  D+  +      L++K    H  N 
Sbjct:    5 YIRVAEDENEEPMEIPSEEDGTVLLSTVAAQFPGACGLRYRSPVSQCMRGVRLVEG-VLHAPEADWGNLVYVVNYPKDNKRKMDEMDAASAVK-----IKRGIQK---TSDLIVLGLPWKTTEQDLKDYFGTFGEVIMVQVKRDAKSGNSKGFGFVRFTDYETQIKVMSQRHMIDGRWCDCKLPNSKYFLEQAGPDEPMRSRKVFVGRCTEDMTADELRQFFMQYGEVTDVFIPKPFRAFAFVTFADDQVAQSLCGEDLIIKGTSVHISNA 266          
BLAST of TAR DNA-binding protein 43 vs. Ensembl Xenopus
Match: jarid2 (jumonji and AT-rich interaction domain containing 2 [Source:Xenbase;Acc:XB-GENE-982166])

HSP 1 Score: 153.295 bits (386), Expect = 3.650e-40
Identity = 79/255 (30.98%), Postives = 140/255 (54.90%), Query Frame = 3
Query:   84 IENKYVRVKGIDNLEIVELPLDLDNTLSFAVLSSQFPYSTGLKYRNSKNNQIRTVRRTDGKFFLSPDLNWDDFLFFCCCSQSKRKMLENPNEKSQIQKKPETLKSIFQKFPDTFDLIAIGLSYDTTENDLTDYLNRFGKLVYCKLKCDDVFGYSRGVAYFRFSGIKSQNLCLSATHVVDKTKIMIRIPNEKINIKERESSKLYVSNVCNTLTREDLRAYFHQFGHVIHVFLPPDKRNFAFVTFLHDKSIELVMKE 848
            +E +Y+RV   +N E +E+P + D T+  + +++QFP + GL+YRN  N  +R VR  +G    +P+  W + ++     +  ++ ++  +  S ++ K    K        T DLI +GL + TTE DL DY + FG+++  ++K D   G+S+G  + RF+  ++Q   +S  H++D      ++PN K   +   S K++V      ++ E+LR +F Q+G V+ VF+P   R FAFVTF  D+  + +  E
Sbjct:   10 MEMEYIRVAEDENEEPMEIPSEDDGTVLLSTVTAQFPGACGLRYRNPVNQCMRGVRLVEG-ILHAPENGWGNLVYVVNYPKDNKRKMDETDASSAVKIKRAVTK--------TSDLIVLGLPWKTTEQDLKDYFSTFGEVIMVQVKKDAKTGHSKGFGFVRFADYETQVKVMSQRHMIDGRWCDCKLPNSKSPDEPMRSRKVFVGRCTEDMSAEELRQFFSQYGEVVDVFIPKPFRAFAFVTFADDQVAQSLCGE 255          
BLAST of TAR DNA-binding protein 43 vs. Ensembl Xenopus
Match: jarid2 (jumonji and AT-rich interaction domain containing 2 [Source:Xenbase;Acc:XB-GENE-982166])

HSP 1 Score: 112.079 bits (279), Expect = 3.151e-26
Identity = 57/192 (29.69%), Postives = 106/192 (55.21%), Query Frame = 3
Query:   84 IENKYVRVKGIDNLEIVELPLDLDNTLSFAVLSSQFPYSTGLKYRNSKNNQIRTVRRTDGKFFLSPDLNWDDFLFFCCCSQSKRKMLENPNEKSQIQKKPETLKSIFQKFPDTFDLIAIGLSYDTTENDLTDYLNRFGKLVYCKLKCDDVFGYSRGVAYFRFSGIKSQNLCLSATHVVDKTKIMIRIPNEKI 659
            +E +Y+RV   +N E +E+P + D T+  + +++QFP + GL+YRN  N  +R VR  +G    +P+  W + ++     +  ++ ++  +  S ++ K    K        T DLI +GL + TTE DL DY + FG+++  ++K D   G+S+G  + RF+  ++Q   +S  H++D      ++PN K+
Sbjct:    1 MEMEYIRVAEDENEEPMEIPSEDDGTVLLSTVTAQFPGACGLRYRNPVNQCMRGVRLVEG-ILHAPENGWGNLVYVVNYPKDNKRKMDETDASSAVKIKRAVTK--------TSDLIVLGLPWKTTEQDLKDYFSTFGEVIMVQVKKDAKTGHSKGFGFVRFADYETQVKVMSQRHMIDGRWCDCKLPNSKV 183          
BLAST of TAR DNA-binding protein 43 vs. Ensembl Xenopus
Match: h2bc21 (H2B clustered histone 21 [Source:Xenbase;Acc:XB-GENE-6452473])

HSP 1 Score: 78.1814 bits (191), Expect = 2.449e-15
Identity = 48/150 (32.00%), Postives = 80/150 (53.33%), Query Frame = 3
Query:  417 DTFDLIAIGLSYDTTENDLTDYLNRFGKLVYCKLKCDDVFGYSRGVAYFRFSGIKSQNLCL-SATHVVDKTKIMIRIPNEKINIKERE-SSKLYVSNVCNTLTREDLRAYFHQFGHVIHVFLPPD-----KRNFAFVTFLHDKSIELVMK 845
            D   +   GLS+DT++ DLT+YL+RFG++V C +K D V G SRG  +  F    S +  L +  H +D   I    P     +K +E   K++V  +    T E ++ YF  FG + ++ LP D     +R F FVT+  ++ ++ +++
Sbjct:   24 DEGKMFIGGLSWDTSKKDLTEYLSRFGEVVDCTIKTDPVTGRSRGFGFVLFKDAVSVDKVLETKEHKLDGKLI---DPKRAKALKGKEPPKKVFVGGLSPETTEEQIKQYFGGFGEIENIELPMDTKTNERRGFCFVTYTGEEPVKKLLE 170          
BLAST of TAR DNA-binding protein 43 vs. Ensembl Xenopus
Match: h2bc21 (H2B clustered histone 21 [Source:Xenbase;Acc:XB-GENE-6452473])

HSP 1 Score: 78.5666 bits (192), Expect = 2.634e-15
Identity = 48/150 (32.00%), Postives = 80/150 (53.33%), Query Frame = 3
Query:  417 DTFDLIAIGLSYDTTENDLTDYLNRFGKLVYCKLKCDDVFGYSRGVAYFRFSGIKSQNLCL-SATHVVDKTKIMIRIPNEKINIKERE-SSKLYVSNVCNTLTREDLRAYFHQFGHVIHVFLPPD-----KRNFAFVTFLHDKSIELVMK 845
            D   +   GLS+DT++ DLT+YL+RFG++V C +K D V G SRG  +  F    S +  L +  H +D   I    P     +K +E   K++V  +    T E ++ YF  FG + ++ LP D     +R F FVT+  ++ ++ +++
Sbjct:   24 DEGKMFIGGLSWDTSKKDLTEYLSRFGEVVDCTIKTDPVTGRSRGFGFVLFKDAVSVDKVLETKEHKLDGKLI---DPKRAKALKGKEPPKKVFVGGLSPETTEEQIKQYFGGFGEIENIELPMDTKTNERRGFCFVTYTGEEPVKKLLE 170          
BLAST of TAR DNA-binding protein 43 vs. Ensembl Xenopus
Match: h2bc21 (H2B clustered histone 21 [Source:Xenbase;Acc:XB-GENE-6452473])

HSP 1 Score: 78.1814 bits (191), Expect = 3.705e-15
Identity = 48/150 (32.00%), Postives = 80/150 (53.33%), Query Frame = 3
Query:  417 DTFDLIAIGLSYDTTENDLTDYLNRFGKLVYCKLKCDDVFGYSRGVAYFRFSGIKSQNLCL-SATHVVDKTKIMIRIPNEKINIKERE-SSKLYVSNVCNTLTREDLRAYFHQFGHVIHVFLPPD-----KRNFAFVTFLHDKSIELVMK 845
            D   +   GLS+DT++ DLT+YL+RFG++V C +K D V G SRG  +  F    S +  L +  H +D   I    P     +K +E   K++V  +    T E ++ YF  FG + ++ LP D     +R F FVT+  ++ ++ +++
Sbjct:   34 DEGKMFIGGLSWDTSKKDLTEYLSRFGEVVDCTIKTDPVTGRSRGFGFVLFKDAVSVDKVLETKEHKLDGKLI---DPKRAKALKGKEPPKKVFVGGLSPETTEEQIKQYFGGFGEIENIELPMDTKTNERRGFCFVTYTGEEPVKKLLE 180          
BLAST of TAR DNA-binding protein 43 vs. Ensembl Mouse
Match: Tardbp (TAR DNA binding protein [Source:MGI Symbol;Acc:MGI:2387629])

HSP 1 Score: 146.747 bits (369), Expect = 3.269e-39
Identity = 81/254 (31.89%), Postives = 142/254 (55.91%), Query Frame = 3
Query:   90 NKYVRVKGIDNLEIVELPLDLDNTLSFAVLSSQFPYSTGLKYRNSKNNQIRTVRRTDGKFFLSPDLNWDDFLFFCCCSQSKRKMLENPNEKSQIQKKPETLKSIFQKFPDTFDLIAIGLSYDTTENDLTDYLNRFGKLVYCKLKCDDVFGYSRGVAYFRFSGIKSQNLCLSATHVVDKTKIMIRIPNEKINIKER-ESSKLYVSNVCNTLTREDLRAYFHQFGHVIHVFLPPDKRNFAFVTFLHDKSIELVMKE 848
            ++Y+RV   +N E +E+P + D T+  + +++QFP + GL+YRN  +  +R VR  +G    +PD  W + ++     +  ++ ++  +  S ++     +K   QK   T DLI +GL + TTE DL DY + FG+++  ++K D   G+S+G  + RF+  ++Q   +S  H++D      ++PN K +  E   S K++V      +T E+L+ +F Q+G V+ VF+P   R FAFVTF  DK  + +  E
Sbjct:    2 SEYIRVTEDENDEPIEIPSEDDGTVLLSTVTAQFPGACGLRYRNPVSQCMRGVRLVEG-ILHAPDAGWGNLVYVVNYPKDNKRKMDETDASSAVK-----VKRAVQK---TSDLIVLGLPWKTTEQDLKDYFSTFGEVLMVQVKKDLKTGHSKGFGFVRFTEYETQVKVMSQRHMIDGRWCDCKLPNSKQSPDEPLRSRKVFVGRCTEDMTAEELQQFFCQYGEVVDVFIPKPFRAFAFVTFADDKVAQSLCGE 246          
BLAST of TAR DNA-binding protein 43 vs. Ensembl Mouse
Match: Tardbp (TAR DNA binding protein [Source:MGI Symbol;Acc:MGI:2387629])

HSP 1 Score: 146.362 bits (368), Expect = 6.537e-39
Identity = 81/254 (31.89%), Postives = 142/254 (55.91%), Query Frame = 3
Query:   90 NKYVRVKGIDNLEIVELPLDLDNTLSFAVLSSQFPYSTGLKYRNSKNNQIRTVRRTDGKFFLSPDLNWDDFLFFCCCSQSKRKMLENPNEKSQIQKKPETLKSIFQKFPDTFDLIAIGLSYDTTENDLTDYLNRFGKLVYCKLKCDDVFGYSRGVAYFRFSGIKSQNLCLSATHVVDKTKIMIRIPNEKINIKER-ESSKLYVSNVCNTLTREDLRAYFHQFGHVIHVFLPPDKRNFAFVTFLHDKSIELVMKE 848
            ++Y+RV   +N E +E+P + D T+  + +++QFP + GL+YRN  +  +R VR  +G    +PD  W + ++     +  ++ ++  +  S ++     +K   QK   T DLI +GL + TTE DL DY + FG+++  ++K D   G+S+G  + RF+  ++Q   +S  H++D      ++PN K +  E   S K++V      +T E+L+ +F Q+G V+ VF+P   R FAFVTF  DK  + +  E
Sbjct:    2 SEYIRVTEDENDEPIEIPSEDDGTVLLSTVTAQFPGACGLRYRNPVSQCMRGVRLVEG-ILHAPDAGWGNLVYVVNYPKDNKRKMDETDASSAVK-----VKRAVQK---TSDLIVLGLPWKTTEQDLKDYFSTFGEVLMVQVKKDLKTGHSKGFGFVRFTEYETQVKVMSQRHMIDGRWCDCKLPNSKQSPDEPLRSRKVFVGRCTEDMTAEELQQFFCQYGEVVDVFIPKPFRAFAFVTFADDKVAQSLCGE 246          
BLAST of TAR DNA-binding protein 43 vs. Ensembl Mouse
Match: Tardbp (TAR DNA binding protein [Source:MGI Symbol;Acc:MGI:2387629])

HSP 1 Score: 146.362 bits (368), Expect = 6.537e-39
Identity = 81/254 (31.89%), Postives = 142/254 (55.91%), Query Frame = 3
Query:   90 NKYVRVKGIDNLEIVELPLDLDNTLSFAVLSSQFPYSTGLKYRNSKNNQIRTVRRTDGKFFLSPDLNWDDFLFFCCCSQSKRKMLENPNEKSQIQKKPETLKSIFQKFPDTFDLIAIGLSYDTTENDLTDYLNRFGKLVYCKLKCDDVFGYSRGVAYFRFSGIKSQNLCLSATHVVDKTKIMIRIPNEKINIKER-ESSKLYVSNVCNTLTREDLRAYFHQFGHVIHVFLPPDKRNFAFVTFLHDKSIELVMKE 848
            ++Y+RV   +N E +E+P + D T+  + +++QFP + GL+YRN  +  +R VR  +G    +PD  W + ++     +  ++ ++  +  S ++     +K   QK   T DLI +GL + TTE DL DY + FG+++  ++K D   G+S+G  + RF+  ++Q   +S  H++D      ++PN K +  E   S K++V      +T E+L+ +F Q+G V+ VF+P   R FAFVTF  DK  + +  E
Sbjct:    2 SEYIRVTEDENDEPIEIPSEDDGTVLLSTVTAQFPGACGLRYRNPVSQCMRGVRLVEG-ILHAPDAGWGNLVYVVNYPKDNKRKMDETDASSAVK-----VKRAVQK---TSDLIVLGLPWKTTEQDLKDYFSTFGEVLMVQVKKDLKTGHSKGFGFVRFTEYETQVKVMSQRHMIDGRWCDCKLPNSKQSPDEPLRSRKVFVGRCTEDMTAEELQQFFCQYGEVVDVFIPKPFRAFAFVTFADDKVAQSLCGE 246          
BLAST of TAR DNA-binding protein 43 vs. Ensembl Mouse
Match: Tardbp (TAR DNA binding protein [Source:MGI Symbol;Acc:MGI:2387629])

HSP 1 Score: 146.362 bits (368), Expect = 6.537e-39
Identity = 81/254 (31.89%), Postives = 142/254 (55.91%), Query Frame = 3
Query:   90 NKYVRVKGIDNLEIVELPLDLDNTLSFAVLSSQFPYSTGLKYRNSKNNQIRTVRRTDGKFFLSPDLNWDDFLFFCCCSQSKRKMLENPNEKSQIQKKPETLKSIFQKFPDTFDLIAIGLSYDTTENDLTDYLNRFGKLVYCKLKCDDVFGYSRGVAYFRFSGIKSQNLCLSATHVVDKTKIMIRIPNEKINIKER-ESSKLYVSNVCNTLTREDLRAYFHQFGHVIHVFLPPDKRNFAFVTFLHDKSIELVMKE 848
            ++Y+RV   +N E +E+P + D T+  + +++QFP + GL+YRN  +  +R VR  +G    +PD  W + ++     +  ++ ++  +  S ++     +K   QK   T DLI +GL + TTE DL DY + FG+++  ++K D   G+S+G  + RF+  ++Q   +S  H++D      ++PN K +  E   S K++V      +T E+L+ +F Q+G V+ VF+P   R FAFVTF  DK  + +  E
Sbjct:    2 SEYIRVTEDENDEPIEIPSEDDGTVLLSTVTAQFPGACGLRYRNPVSQCMRGVRLVEG-ILHAPDAGWGNLVYVVNYPKDNKRKMDETDASSAVK-----VKRAVQK---TSDLIVLGLPWKTTEQDLKDYFSTFGEVLMVQVKKDLKTGHSKGFGFVRFTEYETQVKVMSQRHMIDGRWCDCKLPNSKQSPDEPLRSRKVFVGRCTEDMTAEELQQFFCQYGEVVDVFIPKPFRAFAFVTFADDKVAQSLCGE 246          
BLAST of TAR DNA-binding protein 43 vs. Ensembl Mouse
Match: Tardbp (TAR DNA binding protein [Source:MGI Symbol;Acc:MGI:2387629])

HSP 1 Score: 146.362 bits (368), Expect = 6.537e-39
Identity = 81/254 (31.89%), Postives = 142/254 (55.91%), Query Frame = 3
Query:   90 NKYVRVKGIDNLEIVELPLDLDNTLSFAVLSSQFPYSTGLKYRNSKNNQIRTVRRTDGKFFLSPDLNWDDFLFFCCCSQSKRKMLENPNEKSQIQKKPETLKSIFQKFPDTFDLIAIGLSYDTTENDLTDYLNRFGKLVYCKLKCDDVFGYSRGVAYFRFSGIKSQNLCLSATHVVDKTKIMIRIPNEKINIKER-ESSKLYVSNVCNTLTREDLRAYFHQFGHVIHVFLPPDKRNFAFVTFLHDKSIELVMKE 848
            ++Y+RV   +N E +E+P + D T+  + +++QFP + GL+YRN  +  +R VR  +G    +PD  W + ++     +  ++ ++  +  S ++     +K   QK   T DLI +GL + TTE DL DY + FG+++  ++K D   G+S+G  + RF+  ++Q   +S  H++D      ++PN K +  E   S K++V      +T E+L+ +F Q+G V+ VF+P   R FAFVTF  DK  + +  E
Sbjct:    2 SEYIRVTEDENDEPIEIPSEDDGTVLLSTVTAQFPGACGLRYRNPVSQCMRGVRLVEG-ILHAPDAGWGNLVYVVNYPKDNKRKMDETDASSAVK-----VKRAVQK---TSDLIVLGLPWKTTEQDLKDYFSTFGEVLMVQVKKDLKTGHSKGFGFVRFTEYETQVKVMSQRHMIDGRWCDCKLPNSKQSPDEPLRSRKVFVGRCTEDMTAEELQQFFCQYGEVVDVFIPKPFRAFAFVTFADDKVAQSLCGE 246          
BLAST of TAR DNA-binding protein 43 vs. UniProt/SwissProt
Match: sp|Q28F51|TADBP_XENTR (TAR DNA-binding protein 43 OS=Xenopus tropicalis OX=8364 GN=tardbp PE=2 SV=1)

HSP 1 Score: 153.68 bits (387), Expect = 1.426e-39
Identity = 79/255 (30.98%), Postives = 140/255 (54.90%), Query Frame = 3
Query:   84 IENKYVRVKGIDNLEIVELPLDLDNTLSFAVLSSQFPYSTGLKYRNSKNNQIRTVRRTDGKFFLSPDLNWDDFLFFCCCSQSKRKMLENPNEKSQIQKKPETLKSIFQKFPDTFDLIAIGLSYDTTENDLTDYLNRFGKLVYCKLKCDDVFGYSRGVAYFRFSGIKSQNLCLSATHVVDKTKIMIRIPNEKINIKERESSKLYVSNVCNTLTREDLRAYFHQFGHVIHVFLPPDKRNFAFVTFLHDKSIELVMKE 848
            +E +Y+RV   +N E +E+P + D T+  + +++QFP + GL+YRN  N  +R VR  +G    +P+  W + ++     +  ++ ++  +  S ++ K    K        T DLI +GL + TTE DL DY + FG+++  ++K D   G+S+G  + RF+  ++Q   +S  H++D      ++PN K   +   S K++V      ++ E+LR +F Q+G V+ VF+P   R FAFVTF  D+  + +  E
Sbjct:    1 MEMEYIRVAEDENEEPMEIPSEDDGTVLLSTVTAQFPGACGLRYRNPVNQCMRGVRLVEG-ILHAPENGWGNLVYVVNYPKDNKRKMDETDASSAVKIKRAVTK--------TSDLIVLGLPWKTTEQDLKDYFSTFGEVIMVQVKKDAKTGHSKGFGFVRFADYETQVKVMSQRHMIDGRWCDCKLPNSKSPDEPMRSRKVFVGRCTEDMSAEELRQFFSQYGEVVDVFIPKPFRAFAFVTFADDQVAQSLCGE 246          
BLAST of TAR DNA-binding protein 43 vs. UniProt/SwissProt
Match: sp|Q921F2|TADBP_MOUSE (TAR DNA-binding protein 43 OS=Mus musculus OX=10090 GN=Tardbp PE=1 SV=1)

HSP 1 Score: 148.673 bits (374), Expect = 7.964e-38
Identity = 81/254 (31.89%), Postives = 142/254 (55.91%), Query Frame = 3
Query:   90 NKYVRVKGIDNLEIVELPLDLDNTLSFAVLSSQFPYSTGLKYRNSKNNQIRTVRRTDGKFFLSPDLNWDDFLFFCCCSQSKRKMLENPNEKSQIQKKPETLKSIFQKFPDTFDLIAIGLSYDTTENDLTDYLNRFGKLVYCKLKCDDVFGYSRGVAYFRFSGIKSQNLCLSATHVVDKTKIMIRIPNEKINIKER-ESSKLYVSNVCNTLTREDLRAYFHQFGHVIHVFLPPDKRNFAFVTFLHDKSIELVMKE 848
            ++Y+RV   +N E +E+P + D T+  + +++QFP + GL+YRN  +  +R VR  +G    +PD  W + ++     +  ++ ++  +  S ++     +K   QK   T DLI +GL + TTE DL DY + FG+++  ++K D   G+S+G  + RF+  ++Q   +S  H++D      ++PN K +  E   S K++V      +T E+L+ +F Q+G V+ VF+P   R FAFVTF  DK  + +  E
Sbjct:    2 SEYIRVTEDENDEPIEIPSEDDGTVLLSTVTAQFPGACGLRYRNPVSQCMRGVRLVEG-ILHAPDAGWGNLVYVVNYPKDNKRKMDETDASSAVK-----VKRAVQK---TSDLIVLGLPWKTTEQDLKDYFSTFGEVLMVQVKKDLKTGHSKGFGFVRFTEYETQVKVMSQRHMIDGRWCDCKLPNSKQSPDEPLRSRKVFVGRCTEDMTAEELQQFFCQYGEVVDVFIPKPFRAFAFVTFADDKVAQSLCGE 246          
BLAST of TAR DNA-binding protein 43 vs. UniProt/SwissProt
Match: sp|Q13148|TADBP_HUMAN (TAR DNA-binding protein 43 OS=Homo sapiens OX=9606 GN=TARDBP PE=1 SV=1)

HSP 1 Score: 145.591 bits (366), Expect = 1.004e-36
Identity = 78/246 (31.71%), Postives = 139/246 (56.50%), Query Frame = 3
Query:   90 NKYVRVKGIDNLEIVELPLDLDNTLSFAVLSSQFPYSTGLKYRNSKNNQIRTVRRTDGKFFLSPDLNWDDFLFFCCCSQSKRKMLENPNEKSQIQKKPETLKSIFQKFPDTFDLIAIGLSYDTTENDLTDYLNRFGKLVYCKLKCDDVFGYSRGVAYFRFSGIKSQNLCLSATHVVDKTKIMIRIPNEKINIKER-ESSKLYVSNVCNTLTREDLRAYFHQFGHVIHVFLPPDKRNFAFVTFLHDK 824
            ++Y+RV   +N E +E+P + D T+  + +++QFP + GL+YRN  +  +R VR  +G    +PD  W + ++     +  ++ ++  +  S ++     +K   QK   T DLI +GL + TTE DL +Y + FG+++  ++K D   G+S+G  + RF+  ++Q   +S  H++D      ++PN K +  E   S K++V      +T ++LR +F Q+G V+ VF+P   R FAFVTF  D+
Sbjct:    2 SEYIRVTEDENDEPIEIPSEDDGTVLLSTVTAQFPGACGLRYRNPVSQCMRGVRLVEG-ILHAPDAGWGNLVYVVNYPKDNKRKMDETDASSAVK-----VKRAVQK---TSDLIVLGLPWKTTEQDLKEYFSTFGEVLMVQVKKDLKTGHSKGFGFVRFTEYETQVKVMSQRHMIDGRWCDCKLPNSKQSQDEPLRSRKVFVGRCTEDMTEDELREFFSQYGDVMDVFIPKPFRAFAFVTFADDQ 238          
BLAST of TAR DNA-binding protein 43 vs. UniProt/SwissProt
Match: sp|Q5R5W2|TADBP_PONAB (TAR DNA-binding protein 43 OS=Pongo abelii OX=9601 GN=TARDBP PE=2 SV=1)

HSP 1 Score: 143.665 bits (361), Expect = 5.018e-36
Identity = 77/246 (31.30%), Postives = 139/246 (56.50%), Query Frame = 3
Query:   90 NKYVRVKGIDNLEIVELPLDLDNTLSFAVLSSQFPYSTGLKYRNSKNNQIRTVRRTDGKFFLSPDLNWDDFLFFCCCSQSKRKMLENPNEKSQIQKKPETLKSIFQKFPDTFDLIAIGLSYDTTENDLTDYLNRFGKLVYCKLKCDDVFGYSRGVAYFRFSGIKSQNLCLSATHVVDKTKIMIRIPNEKINIKER-ESSKLYVSNVCNTLTREDLRAYFHQFGHVIHVFLPPDKRNFAFVTFLHDK 824
            ++Y+RV   ++ E +E+P + D T+  + +++QFP + GL+YRN  +  +R VR  +G    +PD  W + ++     +  ++ ++  +  S ++     +K   QK   T DLI +GL + TTE DL +Y + FG+++  ++K D   G+S+G  + RF+  ++Q   +S  H++D      ++PN K +  E   S K++V      +T ++LR +F Q+G V+ VF+P   R FAFVTF  D+
Sbjct:    2 SEYIRVTEDESDEPIEIPSEDDGTVLLSTVTAQFPGACGLRYRNPVSQCMRGVRLVEG-ILHAPDAGWGNLVYVVNYPKDNKRKMDETDASSAVK-----VKRAVQK---TSDLIVLGLPWKTTEQDLKEYFSTFGEVLMVQVKKDLKTGHSKGFGFVRFTEYETQVKVMSQRHMIDGRWCDCKLPNSKQSQDEPLRSRKVFVGRCTEDMTEDELREFFSQYGDVMDVFIPKPFRAFAFVTFADDQ 238          
BLAST of TAR DNA-binding protein 43 vs. UniProt/SwissProt
Match: sp|Q5ZLN5|TADBP_CHICK (TAR DNA-binding protein 43 OS=Gallus gallus OX=9031 GN=TARDBP PE=2 SV=1)

HSP 1 Score: 140.584 bits (353), Expect = 6.653e-35
Identity = 76/254 (29.92%), Postives = 141/254 (55.51%), Query Frame = 3
Query:   90 NKYVRVKGIDNLEIVELPLDLDNTLSFAVLSSQFPYSTGLKYRNSKNNQIRTVRRTDGKFFLSPDLNWDDFLFFCCCSQSKRKMLENPNEKSQIQKKPETLKSIFQKFPDTFDLIAIGLSYDTTENDLTDYLNRFGKLVYCKLKCDDVFGYSRGVAYFRFSGIKSQNLCLSATHVVDKTKIMIRIPNEKINIKER-ESSKLYVSNVCNTLTREDLRAYFHQFGHVIHVFLPPDKRNFAFVTFLHDKSIELVMKE 848
            ++Y+RV   +N E +E+P + D T+  + +++QFP + GL+YRN  +  +  VR  +G    +P+  W + ++     +  ++ ++  +  S ++     +K   QK   T DLI +GL + TTE DL +Y + FG+++  ++K D   G+S+G  + RF+  ++Q   +S  H++D      ++PN K +  E   S K++V      +T ++L+ +F Q+G V+ VF+P   R FAFVTF  D+  + +  E
Sbjct:    2 SEYIRVTEDENDEPIEIPSEDDGTVLLSTVTAQFPGACGLRYRNPVSQCMWGVRLVEG-ILHAPEAGWGNLVYVVNYPKDNKRKMDETDASSAVK-----VKRAVQK---TSDLIVLGLPWKTTEQDLKEYFSTFGEVLMVQVKKDIKTGHSKGFGFVRFTDYETQVKVMSQRHMIDGRWCDCKLPNSKQSPDEPLRSRKVFVGRCTEDMTADELQQFFAQYGEVVDVFIPKPFRAFAFVTFADDQVAQSLCGE 246          
BLAST of TAR DNA-binding protein 43 vs. TrEMBL
Match: A0A2T7PUB6 (Uncharacterized protein OS=Pomacea canaliculata OX=400727 GN=C0Q70_04001 PE=4 SV=1)

HSP 1 Score: 173.711 bits (439), Expect = 7.104e-44
Identity = 97/272 (35.66%), Postives = 148/272 (54.41%), Query Frame = 3
Query:   90 NKYVRVKGIDNLEIVELPLDLDNTLSFAVLSSQFPYSTGLKYRNSKNNQIRTVRRTDGKFFLSPDLNWDDFLFFCCCSQSKRKMLENPNEKSQIQKKPETLKSIFQKFPDTFDLIAIGLSYDTTENDLTDYLNRFGKLVYCKLKCDDVFGYSRGVAYFRFSGIKSQNLCLSATHVVDKTKIMIRIPNEKINIKERESSKLYVSNVCNTLTREDLRAYFHQFGHVIHVFLPPDKRNFAFVTFLHDKSIELVMKEGQTHCFNGARVNVYRVMEK 905
            ++Y++V   D  E +ELP + D TL    LS+QFP S GLKYRN     +R +R +DG+ +  PD +W   +FFC   + + K       +  I K P++  S  QK     DLI +GL + +TE DL +Y ++FG+L+  ++K D   G S+G  + RF+  +SQ  C+S  H++D     +RIPN K   +   + K++V      +T EDLR YF +FG V+ VF+P   R FAFV+F      + +   G+ H   GA V++     K
Sbjct:    2 SQYIKVVAEDGDEPLELPTEEDGTLLLTTLSAQFPGSCGLKYRNPDTGTMRGIRLSDGRLY-PPDNDWGKQVFFCVFPKGEGKREPTVTVEHPIVKPPKS--SSRQK---CSDLIVLGLPWKSTEEDLRNYFSQFGELLMVQVKKDPKTGQSKGFGFVRFAEYESQLKCMSQRHMIDGRWCDVRIPNSKEGAQHMMNRKVFVGRCTEDMTAEDLRQYFAKFGEVVDVFIPKPFRAFAFVSFADPDVAQSLC--GEDHIIKGASVHISGAAPK 265          
BLAST of TAR DNA-binding protein 43 vs. TrEMBL
Match: R7TFC3 (Uncharacterized protein OS=Capitella teleta OX=283909 GN=CAPTEDRAFT_175992 PE=4 SV=1)

HSP 1 Score: 170.629 bits (431), Expect = 6.960e-43
Identity = 98/276 (35.51%), Postives = 154/276 (55.80%), Query Frame = 3
Query:   90 NKYVRVKGIDNLEIVELPLDLDNTLSFAVLSSQFPYSTGLKYRNSKNNQIRTVRRTDGKFFLSPDLNWDDFLFFCC-CSQSKRKM---LENPNEKSQIQKKPETLKSIFQKFPDTFDLIAIGLSYDTTENDLTDYLNRFGKLVYCKLKCDDVFGYSRGVAYFRFSGIKSQNLCLSATHVVDKTKIMIRIPNEKINIKERESSKLYVSNVCNTLTREDLRAYFHQFGHVIHVFLPPDKRNFAFVTFLHDKSIELVMKEGQTHCFNGARVNVYRVMEK 905
            N+Y++V   +N E +ELP + D TL  + L++QFP S GLKYRN  +  +R +R  DG+    PD  W + +F+C    ++KRK    LENP  K+   K+ E  K          DLI +GL + +TE+DL  Y ++FG+L+  ++K D   G S+G  + RF+  ++Q  CL+  H++D     +RIPN +   +   + K+++      +T +DLR+YF++FG V+ VF+P   R FAFVTF   +    +   G+ H   GA V+V     K
Sbjct:    2 NQYLQVAEDENEEPIELPSEEDGTLLLSTLAAQFPGSCGLKYRNPDSGVLRGIRLADGRLH-PPDGMWGNHIFYCVFPKENKRKGEEGLENPMAKT---KRVEKHKCS--------DLIVLGLPWKSTEDDLQAYFSQFGELLMVQVKRDLKTGQSKGFGFVRFADYEAQLKCLAVRHMIDGRWCDVRIPNSREGTQHIVNRKVFIGRCTEDMTADDLRSYFNKFGEVVDVFIPKPFRAFAFVTFADPEVAHALC--GEDHIIKGASVHVSNAAPK 263          
BLAST of TAR DNA-binding protein 43 vs. TrEMBL
Match: A0A0L7KS51 (TAR DNA-binding protein 43 OS=Operophtera brumata OX=104452 GN=OBRU01_22143 PE=4 SV=1)

HSP 1 Score: 167.548 bits (423), Expect = 4.631e-42
Identity = 95/266 (35.71%), Postives = 140/266 (52.63%), Query Frame = 3
Query:   93 KYVRVKGIDNLEIVELPLDLDNTLSFAVLSSQFPYSTGLKYRNSKNNQIRTVRRTDGKFFLSPDLNWDDFLFFCC-CSQSKRKMLENPNEKSQIQKKPETLKSIFQKFPDTFDLIAIGLSYDTTENDLTDYLNRFGKLVYCKLKCDDVFGYSRGVAYFRFSGIKSQNLCLSATHVVDKTKIMIRIPNEKINIKERESSKLYVSNVCNTLTREDLRAYFHQFGHVIHVFLPPDKRNFAFVTFLHDKSIELVMKEGQTHCFNGARVNV 887
            +Y+ V   +N E +ELP++ D TL    +S+QFP   GLKYR+ +   IR +R  DG+ +  P+  W + L+ C    +SKRK  EN +  S   K+ + L S         DLI +GL +  TE  + +Y  +FG+++  +LK D   G S+G A+ RF+   SQ   L+  H++D     +RIPN K         K++V      L+  DLR YF QFG V  VF+P   R F+F+TFL  +  + +   GQ H   G  VNV
Sbjct:    4 EYLPVAEDENEEPIELPVEEDGTLMLTTVSAQFPGCCGLKYRHPETKTIRGIRLRDGRLYAPPE-GWGNQLYICSFPKESKRKSGENSDASSSKNKRNDNLCS---------DLIVLGLPWKATEQTVREYFEKFGEVLMAQLKRDPKTGMSKGFAFIRFASYTSQMRVLAQRHMIDGRWCDVRIPNSKEGSVASMPCKVFVGRCTEDLSANDLREYFSQFGEVTDVFIPKPFRAFSFITFLDPEVAQSLC--GQDHIIKGVSVNV 257          
BLAST of TAR DNA-binding protein 43 vs. TrEMBL
Match: A0A0K8TR16 (Putative rna-binding protein musashi/mrna cleavage and polyadenylation factor i complex OS=Tabanus bromius OX=304241 PE=2 SV=1)

HSP 1 Score: 167.933 bits (424), Expect = 5.565e-42
Identity = 98/275 (35.64%), Postives = 147/275 (53.45%), Query Frame = 3
Query:   93 KYVRVKGIDNLEIVELPLDLDNTLSFAVLSSQFPYSTGLKYRNSKNNQIRTVRRTDGKFFLSPDLNWDDFLFFCC-CSQSKRKM---LENPNEKSQIQKKPETLKSIFQKFPDTFDLIAIGLSYDTTENDLTDYLNRFGKLVYCKLKCDDVFGYSRGVAYFRFSGIKSQNLCLSATHVVDKTKIMIRIPNEKINIKERESSKLYVSNVCNTLTREDLRAYFHQFGHVIHVFLPPDKRNFAFVTFLHDKSIELVMKEGQTHCFNGARVNVYRVMEK 905
            +Y++V   +  E +ELPL+ D TL    L +QFP + GLKYRN ++  IR VR  +G+F   P+  W    FFC    ++KRK    LEN   K+   K+ ET +          DLI +GL Y TTE +L D+  +FG+++  ++K D   G S+G  + RFS  + Q   L+  H++D     +++PN K  +  +   K+YV  V   LT +DL+ YF +FG V  VF+P   R F+FVTFL  +  + +   G+ H   G  V+V     K
Sbjct:    4 EYLQVSEEEGDEPIELPLEEDGTLLITTLQAQFPCACGLKYRNQESKSIRGVRLNEGRFHPPPENGWGSEKFFCVFPKENKRKSDDSLENSTAKT---KRIETKQRCT-------DLIILGLPYKTTEQNLRDHFEKFGEVLMAEIKKDTKTGQSKGFGFVRFSSYEVQMRVLATRHLIDGRWCEVKVPNSKEGLVHQVPCKVYVGRVTEDLTADDLKEYFSKFGEVTDVFIPKSFRAFSFVTFLDPEVAQSLC--GEDHIIKGVSVHVSNAAPK 266          
BLAST of TAR DNA-binding protein 43 vs. TrEMBL
Match: A0A087TT60 (TAR DNA-binding protein 43 (Fragment) OS=Stegodyphus mimosarum OX=407821 GN=X975_17982 PE=4 SV=1)

HSP 1 Score: 166.777 bits (421), Expect = 1.769e-41
Identity = 96/278 (34.53%), Postives = 140/278 (50.36%), Query Frame = 3
Query:   96 YVRVKGIDNLEIVELPLDLDNTLSFAVLSSQFPYSTGLKYRNSKNNQIRTVRRTDGKFFLSPDLNWDDFLFFCC---CSQSKRKMLENPNEKSQIQKKPETLKSIFQKFPDTFDLIAIGLSYDTTENDLTDYLNRFGKLVYCKLKCDDVFGYSRGVAYFRFSGIKSQNLCLSATHVVDKTKIMIRIPNEKINIKERESSKLYVSNVCNTLTREDLRAYFHQFGHVIHVFLPPDKRNFAFVTFLHDKSIELVMKEGQTHCFNGARVNVYRVMEKDLLTN 920
            YV+V   +  E +E+P + D TL    L++QFP + GLKYRN     +R VR TDGK    P   W + L+ C     +++KRK  +     S   K+ ET            DLI +GL + TTE +L  Y   FG+++  ++K D   G S+G  + RFS  +SQ   LS  H++D     +RIPN K       + K+++      +T +DL  YF +FG V  VF+P   R FAFVTFLH +  + +   G+ H   GA + V   + K    N
Sbjct:    5 YVQVAEDEGEEPIEVPCEEDGTLLLTTLAAQFPGTCGLKYRNPGTGTMRGVRVTDGKLLPPPGSGWGNSLYICVFPKVTENKRKSCDQLENSSAKTKRMETKHKCS-------DLIVLGLPWKTTEQELRQYFESFGEVLMAQVKKDPKTGQSKGFGFIRFSNYESQARALSKRHLIDGRWCDVRIPNSKDGQVAELNRKVFIGRCTEDITADDLEEYFSKFGEVTDVFIPKPFRAFAFVTFLHPEVAQSLC--GEDHIVKGASLLVSSAVPKSANAN 273          
BLAST of TAR DNA-binding protein 43 vs. Ensembl Cavefish
Match: tardbpl (TAR DNA binding protein [Source:NCBI gene;Acc:103025275])

HSP 1 Score: 140.584 bits (353), Expect = 6.293e-37
Identity = 81/271 (29.89%), Postives = 144/271 (53.14%), Query Frame = 3
Query:   96 YVRVKGIDNLEIVELPLDLDNTLSFAVLSSQFPYSTGLKYRNSKNNQIRTVRRTDGKFFLSPDLNWDDFLFFCCCSQSKRKMLENPNEKSQIQKKPETLKSIFQKFPDTFDLIAIGLSYDTTENDLTDYLNRFGKLVYCKLKCDDVFGYSRGVAYFRFSGIKSQNLCLSATHVVDKTKIMIRIPNEKINIKER------ESSKLYVSNVCNTLTREDLRAYFHQFGHVIHVFLPPDKRNFAFVTFLHDKSI------ELVMKEGQTHCFNG 872
            Y+RV   +N E +E+P + D T+  + +++QFP + GL+YR+  +  +R VR  +G    +PD +W + ++     +  ++ ++  +  S ++     +K   QK   T DLI +GL + T+E DL DY + FG+++  ++K D   G S+G  + RF+  ++Q   +S  H++D      ++PN K  +++        S K++V      +T +DLR +F Q+G V  VF+P   R FAFVTF  D+        +L++K    H  N 
Sbjct:    5 YIRVAEDENEEPMEIPSEEDGTVLLSTVAAQFPGACGLRYRSPVSQCMRGVRLVEG-VLHAPDADWGNLVYVVNYPKDNKRKMDEMDAASAVK-----IKRGIQK---TSDLIVLGLPWKTSEQDLKDYFSTFGEVIMVQVKRDVKTGNSKGFGFVRFTDYETQIKVMSQRHMIDGRWCDCKLPNSKYFLEQAGPDEPMRSRKVFVGRCTEDMTADDLRQFFMQYGEVTDVFIPKPFRAFAFVTFADDQVAQSLCGEDLIIKGTSVHISNA 266          
BLAST of TAR DNA-binding protein 43 vs. Ensembl Cavefish
Match: tardbpl (TAR DNA binding protein [Source:NCBI gene;Acc:103025275])

HSP 1 Score: 142.124 bits (357), Expect = 1.501e-36
Identity = 81/270 (30.00%), Postives = 144/270 (53.33%), Query Frame = 3
Query:   96 YVRVKGIDNLEIVELPLDLDNTLSFAVLSSQFPYSTGLKYRNSKNNQIRTVRRTDGKFFLSPDLNWDDFLFFCCCSQSKRKMLENPNEKSQIQKKPETLKSIFQKFPDTFDLIAIGLSYDTTENDLTDYLNRFGKLVYCKLKCDDVFGYSRGVAYFRFSGIKSQNLCLSATHVVDKTKIMIRIPNEKINIKER------ESSKLYVSNVCNTLTREDLRAYFHQFGHVIHVFLPPDKRNFAFVTFLHDKSI------ELVMKEGQTHCFN 869
            Y+RV   +N E +E+P + D T+  + +++QFP + GL+YR+  +  +R VR  +G    +PD +W + ++     +  ++ ++  +  S ++     +K   QK   T DLI +GL + T+E DL DY + FG+++  ++K D   G S+G  + RF+  ++Q   +S  H++D      ++PN K  +++        S K++V      +T +DLR +F Q+G V  VF+P   R FAFVTF  D+        +L++K    H  N
Sbjct:    5 YIRVAEDENEEPMEIPSEEDGTVLLSTVAAQFPGACGLRYRSPVSQCMRGVRLVEG-VLHAPDADWGNLVYVVNYPKDNKRKMDEMDAASAVK-----IKRGIQK---TSDLIVLGLPWKTSEQDLKDYFSTFGEVIMVQVKRDVKTGNSKGFGFVRFTDYETQIKVMSQRHMIDGRWCDCKLPNSKYFLEQAGPDEPMRSRKVFVGRCTEDMTADDLRQFFMQYGEVTDVFIPKPFRAFAFVTFADDQVAQSLCGEDLIIKGTSVHISN 265          
BLAST of TAR DNA-binding protein 43 vs. Ensembl Cavefish
Match: tardbp (TAR DNA-binding protein 43-like [Source:NCBI gene;Acc:103044966])

HSP 1 Score: 129.798 bits (325), Expect = 3.288e-32
Identity = 81/250 (32.40%), Postives = 132/250 (52.80%), Query Frame = 3
Query:   96 YVRVKGIDNLEIVELPLDLDNTLSFAVLSSQFPYSTGLKYRNSKNNQIRTVRRTDGKFFLSPDLNWDDFLFFC------CCSQSKRKMLENPNEKSQIQKKPETLKSIFQKFPDTFDLIAIGLSYDTTENDLTDYLNRFGKLVYCKLKCDDVFGYSRGVAYFRFSGIKSQNLCLSATHVVDKTKIMIRIPNEKINIKE-RESSKLYVSNVCNTLTREDLRAYFHQFGHVIHVFLPPDKRNFAFVTFLHDK 824
            Y+RV   +N E +E+P + D T+  + +S+QFP + GL+YR+  +  +R VR  +G    +P+  W + ++            +KRKM E       I+     +K    K   T DLI +GL + T+E DL DY + FG+++  ++K D   G S+G  + RF   ++Q+  ++  H++D      ++PN K    E   S K++V      +T +DLR +F Q+G V  VF+P   R FAFVTF  D+
Sbjct:    5 YIRVAEEENEEPMEIPSEDDGTVLLSTVSAQFPGACGLRYRSPISQCMRGVRLVEG-VLHAPENGWGNLVYVVNYPKEPALPDNKRKMDE-------IEASSAKMKRGDHK---TSDLIVLGLPWKTSEQDLKDYFSTFGEVIMVQVKRDVKTGNSKGFGFVRFGEWETQSKVIAQRHMIDGRWCDCKLPNSKQGPDEPMRSRKVFVGRCTEDMTADDLRQFFMQYGEVTDVFIPKPFRAFAFVTFADDQ 243          
BLAST of TAR DNA-binding protein 43 vs. Ensembl Cavefish
Match: hnrnpabb (heterogeneous nuclear ribonucleoprotein A/B [Source:NCBI gene;Acc:103033389])

HSP 1 Score: 88.1965 bits (217), Expect = 1.564e-18
Identity = 48/163 (29.45%), Postives = 83/163 (50.92%), Query Frame = 3
Query:  417 DTFDLIAIGLSYDTTENDLTDYLNRFGKLVYCKLKCDDVFGYSRGVAYFRFSGIKS-QNLCLSATHVVDKTKIMIRIPNEKINIKERESSKLYVSNVCNTLTREDLRAYFHQFGHVIHVFLPPD-----KRNFAFVTFLHDKSIELVMKEGQTHCFNGARVNV 887
            D   +   GLS+DT++ DL DY ++FG++  C +K D   G SRG  +  F    S + +     H +D  +I    P + + +K+    K++V  +    T E +R YF  FG +  + LP D     +R F F+TF  + +++ +M E + H  NG++  +
Sbjct:   51 DAGKMFVGGLSWDTSKKDLKDYFSKFGEVTDCTIKMDSNTGRSRGFGFILFKEAASVEKVLQQKEHRLDGRQI---DPKKAMAMKKDPVKKIFVGGLNPETTEEKIREYFGAFGEIESIELPTDPKTNKRRGFVFITFKEESAVKKIM-EKKYHTVNGSKCEI 209          
BLAST of TAR DNA-binding protein 43 vs. Ensembl Cavefish
Match: hnrnpabb (heterogeneous nuclear ribonucleoprotein A/B [Source:NCBI gene;Acc:103033389])

HSP 1 Score: 87.8113 bits (216), Expect = 1.566e-18
Identity = 48/163 (29.45%), Postives = 83/163 (50.92%), Query Frame = 3
Query:  417 DTFDLIAIGLSYDTTENDLTDYLNRFGKLVYCKLKCDDVFGYSRGVAYFRFSGIKS-QNLCLSATHVVDKTKIMIRIPNEKINIKERESSKLYVSNVCNTLTREDLRAYFHQFGHVIHVFLPPD-----KRNFAFVTFLHDKSIELVMKEGQTHCFNGARVNV 887
            D   +   GLS+DT++ DL DY ++FG++  C +K D   G SRG  +  F    S + +     H +D  +I    P + + +K+    K++V  +    T E +R YF  FG +  + LP D     +R F F+TF  + +++ +M E + H  NG++  +
Sbjct:   51 DAGKMFVGGLSWDTSKKDLKDYFSKFGEVTDCTIKMDSNTGRSRGFGFILFKEAASVEKVLQQKEHRLDGRQI---DPKKAMAMKKDPVKKIFVGGLNPETTEEKIREYFGAFGEIESIELPTDPKTNKRRGFVFITFKEESAVKKIM-EKKYHTVNGSKCEI 209          
BLAST of TAR DNA-binding protein 43 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000009806.1 (pep scaffold:Pmarinus_7.0:GL479354:9188:12030:-1 gene:ENSPMAG00000008859.1 transcript:ENSPMAT00000009806.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 137.502 bits (345), Expect = 4.073e-36
Identity = 84/283 (29.68%), Postives = 144/283 (50.88%), Query Frame = 3
Query:   90 NKYVRVKGIDNLEIVELPLDLDNTLSFAVLSSQFPYSTGLKYRNSKNNQIRTVRRTDGKFFLSPDLNWDDFLFF-------CCCS-QSKRKMLENPNEKSQIQKKPETLKSIFQKFPDTFDLIAIGLSYDTTENDLTDYLNRFGKLVYCKLKCDDVFGYSRGVAYFRFSGIKSQNLCLSATHVVDKTKIMIRIPNEKINIKERESSKLYVSNVCNTLTREDLRAYFHQFGHVIHVFLPPDKRNFAFVTFLHDKSIELVMKEGQTHCFNGARVNVYRVMEKDLL 914
            ++YV++   +N   VE+P + D TL  + +++QFP + GL+YR       R VR  DG     P+  W  + F+       C    ++KRKM     E+  +    + L+S     P   DL+ +GL + TTE++L DY + FG +V  ++K D   G S+G  + RF+  +SQ   +   H++       ++P  K+   + + ++++V      +T EDLR++F QFG V  V++P   R+F FVTF ++   + +   GQ     GA V++     K+ L
Sbjct:    2 SEYVKIAEDENELPVEVPCEDDGTLLVSNVAAQFPGAVGLRYRPPDAQSFRGVRLVDG-VLHPPENGWASYTFYVNFPKDPCVLGLENKRKM-----EEVDMASASKMLRSE----PRVSDLVVLGLPWTTTEDELKDYFSAFGSVVLSQIKTDPATGKSKGYGFVRFADHESQLKAMGMRHMIGGRWCDAKLPQSKMYPTDPDRNRIFVGRCPEDITPEDLRSFFGQFGDVTDVYIPKPFRSFGFVTFANEHVAQSLC--GQDVIVKGASVHIASAEPKNQL 272          
BLAST of TAR DNA-binding protein 43 vs. Ensembl Sea Lamprey
Match: TARDBP (TAR DNA binding protein [Source:HGNC Symbol;Acc:HGNC:11571])

HSP 1 Score: 92.8189 bits (229), Expect = 1.008e-21
Identity = 61/168 (36.31%), Postives = 90/168 (53.57%), Query Frame = 3
Query:  330 KRKMLENPNEKSQIQKKPETLKSIFQKFPDTFDLIAIGLSYDTTENDLTDYLNRFGKLVYCKLKCDDVFGYSRGVAYFRFSGIKSQNLCLSATHVVDKTKIMIRIPNEK---INIKERESSKLYVSNVCNTLTREDLRAYFHQFGHVIHVFLPPDKRNFAFVTFLHDK 824
            KRKM E   E S + K    +K   QK   T DLI +GL +  +E D+ DY + FG+++  ++K D   G S+G  + RF   ++Q   L+  H++D      ++PN K   +    R S K++V      +T +DLR +F QFG V  VF+P   R FAFVTF  D+
Sbjct:    3 KRKMDEA--EMSNVAK----VKRSVQK---TSDLIVLGLPWKASEQDIRDYFSTFGEVLMAQVKRDIKTGNSKGFGFVRFRDYETQLKVLAQRHMIDGRWCDCKLPNSKEQQVGDAFR-SRKIFVGRCTEDITADDLRQFFSQFGEVTDVFIPKPFRAFAFVTFSDDQ 160          
BLAST of TAR DNA-binding protein 43 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004893.1 (pep scaffold:Pmarinus_7.0:GL479484:4:2056:-1 gene:ENSPMAG00000004449.1 transcript:ENSPMAT00000004893.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 63.929 bits (154), Expect = 1.053e-11
Identity = 52/186 (27.96%), Postives = 85/186 (45.70%), Query Frame = 3
Query:  414 PDTF-DLIAIGLSYDTTENDLTDYLNRFGKLVYCKLKCDDVFGYSRGVAYFRFSGIKSQNLCLSAT-HVVDKTKIMIR---------IPNEKINIKERESSKLYVSNVCNTLTREDLRAYFHQFG--HVIHVFLPPD---KRNFAFVTF-LHDKSIELVMKEGQTHCFNGARVNVYRVMEKDLLTN 920
            P+ F  L   GLS++TTE  L  Y  ++G L  C +  D     SRG  +  FS +   +  +SA  H +D   +  +          P   +++K     K++V  + +    E LR YF ++G   ++ V    +   KR FAFVTF  HD   ++V++  + H  NG    + + + K  L N
Sbjct:    7 PEQFRKLFVGGLSFETTEEGLRQYFEQWGSLTDCVVMKDTQSKRSRGFGFVTFSSMSEVDAAMSARPHKIDGRMVEPKRAVSREDSMRPGAHLSVK-----KIFVGGIKDDTDEEHLRDYFEKYGRIEIVEVMTERESGKKRGFAFVTFNDHDPVDKIVVQ--KYHTINGHNCEIRKALPKQELQN 185          
BLAST of TAR DNA-binding protein 43 vs. Ensembl Sea Lamprey
Match: HNRNPA2B1 (heterogeneous nuclear ribonucleoprotein A2/B1 [Source:HGNC Symbol;Acc:HGNC:5033])

HSP 1 Score: 63.929 bits (154), Expect = 1.271e-11
Identity = 48/164 (29.27%), Postives = 75/164 (45.73%), Query Frame = 3
Query:  363 SQIQKKPETLKSIFQKFPDTFDLIAIGLSYDTTENDLTDYLNRFGKLVYCKLKCDDVFGYSRGVAYFRFSGIKSQNLCLSAT-HVVDKTKIMIR--------IPNEKINIKERESSKLYVSNVCNTLTREDLRAYFHQFGHVIHVFLPPD-----KRNFAFVTF 812
            S + K+PE ++ +F            GLS++TTE  L +Y  ++G +V C +  D     SRG  +  +S ++  N  + A  H VD   +  +         P  ++ +K     KL+V  + +      LR YF +FG V  V +  D     KR FAFVTF
Sbjct:    4 SGMPKEPEQMRKLF----------IGGLSFETTEESLREYYEQWGTIVDCVVMKDPSSKRSRGFGFITYSVMEEVNSAMQARPHTVDGRVVEAKRAVPRDDSRPGIQVTVK-----KLFVGGIKDNTDESHLRDYFSKFGRVESVDMVTDKQTGKKRGFAFVTF 152          
BLAST of TAR DNA-binding protein 43 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007723.1 (pep scaffold:Pmarinus_7.0:GL496487:1152:2091:-1 gene:ENSPMAG00000006977.1 transcript:ENSPMAT00000007723.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 53.9138 bits (128), Expect = 2.150e-9
Identity = 29/102 (28.43%), Postives = 50/102 (49.02%), Query Frame = 3
Query:  354 NEKSQIQKKPETLKSIFQKFPDTFDLIAIGLSYDTTENDLTDYLNRFGKLVYCKLKCDDVFGYSRGVAYFRFSGIKSQNLCLSATHVVDKTKIMIRIPNEKI 659
            N++   +     +  I +    T DLI +GL +   E DL DY    G ++  ++K D   G S+G  + RFS  +SQ   +S  H++      +++PN K+
Sbjct:    2 NKRKMDESDAWNVAKIKRSVQKTSDLIVLGLPWKCNEQDLRDYFTEVGDVLMVQVKRDAKSGTSKGFGFVRFSEFESQLKAISQRHLIGGRWCDVKLPNTKV 103          
BLAST of TAR DNA-binding protein 43 vs. Ensembl Yeast
Match: HRP1 (Subunit of cleavage factor I; cleavage factor I is a five-subunit complex required for the cleavage and polyadenylation of pre-mRNA 3' ends; RRM-containing heteronuclear RNA binding protein and hnRNPA/B family member that binds to poly (A) signal sequences; required for genome stability [Source:SGD;Acc:S000005483])

HSP 1 Score: 66.2402 bits (160), Expect = 6.314e-12
Identity = 38/139 (27.34%), Postives = 68/139 (48.92%), Query Frame = 3
Query:  441 GLSYDTTENDLTDYLNRFGKLVYCKLKCDDVFGYSRGVAYFRFSGIKSQNLCLSATHVVDKTKIMIRIPNEKINIKERE-SSKLYVSNVCNTLTREDLRAYFHQFGHVIHVFLPPDK-----RNFAFVTFLHDKSIELV 839
            GL++DTTE++L +Y  ++G +   K+  D   G SRG  +  F    S +  +   H++D   I    P   I   E++ + K++V  +   +  ++   +F Q+G +I   L  DK     R F FVT+    +++ V
Sbjct:  165 GLNWDTTEDNLREYFGKYGTVTDLKIMKDPATGRSRGFGFLSFEKPSSVDEVVKTQHILDGKVI---DPKRAIPRDEQDKTGKIFVGGIGPDVRPKEFEEFFSQWGTIIDAQLMLDKDTGQSRGFGFVTYDSADAVDRV 300          
BLAST of TAR DNA-binding protein 43 vs. Ensembl Nematostella
Match: EDO44940 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RU25])

HSP 1 Score: 136.346 bits (342), Expect = 5.272e-36
Identity = 85/270 (31.48%), Postives = 141/270 (52.22%), Query Frame = 3
Query:   96 YVRVKGIDNL----EIVELPLDLDNTLSFAVLSSQFPYSTGLKYRNSKNNQIRTVRRTDGKFFLSPDLNWDDFLFFCCCSQSKRKMLENPNEKSQIQKKPETLKSIFQKFPDTFDLIAIGLSYDTTENDLTDYLNRFGKLVYCKLKCDDVFGYSRGVAYFRFSGIKSQNLCLSATHVVDKTKIMIRI--PNEKINIKERESSKLYVSNVCNTLTREDLRAYFHQFGHVIHVFLPPDKRNFAFVTFLHDKSIELVMKEGQTHCFNGARVNV 887
            YVRV  +D+     + +E+  + D TL  + ++ QFP + GL+YRN +    R VR  +   +   +  W D LF    S++     +   E+S I K+PET  +  +   D  DLI +GL Y TTE+++ +Y  RFG++ +C++K D     SRG  + RF   +     LS +H +      +R+  P E++N+ +    KL+V  +  + T + L  YF QFG V  V++P   R+F FVTF   +  + V+   Q H  +G+ +N+
Sbjct:    5 YVRV--VDDETCPDQAIEIEAEEDGTLLLSNVNGQFPGACGLRYRNPETQAFRGVRLVEDVLYPPFEDGWGDTLFLVVPSKAADSASKRKIEESPIGKEPETKITKVEGV-DVGDLIVLGLPYATTESEMKEYFTRFGEIDFCEVKLDPNTRRSRGFGFVRFKKDEDAKNVLSTSHRIQGRLCEVRLPRPKEELNVPK----KLFVGRLPESTTEKTLMEYFAQFGEVTDVYIPKPFRHFGFVTFASGELAKKVLS--QNHRISGSLLNI 265          
BLAST of TAR DNA-binding protein 43 vs. Ensembl Nematostella
Match: EDO39879 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S8S5])

HSP 1 Score: 71.2478 bits (173), Expect = 2.785e-14
Identity = 47/169 (27.81%), Postives = 78/169 (46.15%), Query Frame = 3
Query:  441 GLSYDTTENDLTDYLNRFGKLVYCKLKCDDVFGYSRGVAYFRFSGIKSQNLCL-SATHVVDKTKI--MIRIPNEKINIKERESSKLYVSNVCNTLTREDLRAYFHQFGHVIHVFLPPDK-----RNFAFVTFLHDKSIELVMKEGQTHCFNGARVNVYRVMEKDLLTNI 923
            GLS+ TT   L  +  +FG+L  C +  D V   SRG  +  F   K+ ++ L S    +D  KI   + +P          + K+++  +    + ED++ YF QFG +    L  DK     R F FVTF  + S +    + Q H  N  +V V +   K+++ ++
Sbjct:    6 GLSWQTTAEGLRQHFEKFGELKECVVMRDPVTKRSRGFGFLTFKDPKAVDVVLNSGAQELDGKKIDPKLAVPKRAPAKMVTTTKKIFIGGLSTNTSEEDMKKYFSQFGKITETMLMFDKATQRHRGFGFVTFESENSADKAC-DTQYHLINNKKVEVKKAQPKEVMYSL 173          
BLAST of TAR DNA-binding protein 43 vs. Ensembl Nematostella
Match: EDO49349 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RG33])

HSP 1 Score: 67.0106 bits (162), Expect = 6.208e-13
Identity = 49/150 (32.67%), Postives = 76/150 (50.67%), Query Frame = 3
Query:  441 GLSYDTTENDLTDYLNRFGKLVYCKLKCDDVFGYSRGVAYFRFSGIKSQNLCLSAT-HVVDKTKIMIR--IPNEKINIKERESS--KLYVSNVCNTLTREDLRAYFHQF------GHVIHVFLPPDK------RNFAFVTFLHDKSIELV 839
            GL+++TTE  L DY +++G +V C +   D  G SRG  +  +    S N  L    HV+D  +I  +  +P ++    E  S   K++V  + +T   ED++ YF+        G VI V L  D+      R FAFVTF +D+ +E V
Sbjct:    6 GLNWNTTEEGLKDYFSQWGTIVDCVIMKRD--GRSRGFGFVTYESSDSVNEVLKKKDHVLDDREIEPKRSVPRDESGAPEAMSKTRKIFVGGLASTTVEEDIKEYFNSLCRKNGMGEVIDVDLKRDRDNPKRIRGFAFVTFDNDEIVEKV 153          
BLAST of TAR DNA-binding protein 43 vs. Ensembl Nematostella
Match: EDO38417 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SCX6])

HSP 1 Score: 56.9954 bits (136), Expect = 7.661e-9
Identity = 45/173 (26.01%), Postives = 80/173 (46.24%), Query Frame = 3
Query:  417 DTFDLIAIGLSYDTTENDLTDYLNRFGKLVYCKLKCDDVFGYSRGVAYFRFSGIKSQNLCLSAT--HVVDKTKIMIRIPNEKINIKERESSKLYVSNVCNTLTREDLRAYFHQ-FGHVIHVFLPPD-----KRNFAFVTFLHDKSIELVMKEGQTHCFNGARVNVYRVMEKDL 911
            D   L   GLSY+TT+  L +Y +++G+LV   +K D + G  RG A+ +F      +  L+    HV+D   I  +              K++V  +    + E +R YF + +  V  +    +     +R F FV+F  + +++ +  E Q H   G +V V R + K++
Sbjct:   27 DIGKLFVGGLSYETTKESLKEYFSKYGELVGVDIKMDALTGRPRGFAFVQFKHQSEADAVLNQVDPHVLDGRTIDPKPAAPIGKPPHLRVKKIFVGGLKPETSDEKIREYFGKAYAPVKEIEYITEHSSNRRRGFCFVSFDSEDTVDKIC-ETQFHNIEGNKVEVKRALPKEV 198          
BLAST of TAR DNA-binding protein 43 vs. Ensembl Nematostella
Match: EDO39223 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SAN4])

HSP 1 Score: 48.521 bits (114), Expect = 6.589e-6
Identity = 19/55 (34.55%), Postives = 36/55 (65.45%), Query Frame = 3
Query:  444 LSYDTTENDLTDYLNRFGKLVYCKLKCDDVFGYSRGVAYFRFSGIKSQNLCLSAT 608
            LS+D+T+ ++T+   +FG + YCK+  D +  +S+G A+ ++   +S   CL+AT
Sbjct:  286 LSFDSTQKNITNLFKQFGDIAYCKVVVDHLTQHSKGSAFVKYRSAESVTQCLAAT 340          
BLAST of TAR DNA-binding protein 43 vs. Ensembl Medaka
Match: tardbpl (TAR DNA binding protein [Source:NCBI gene;Acc:101173545])

HSP 1 Score: 148.288 bits (373), Expect = 9.419e-40
Identity = 81/252 (32.14%), Postives = 140/252 (55.56%), Query Frame = 3
Query:   96 YVRVKGIDNLEIVELPLDLDNTLSFAVLSSQFPYSTGLKYRNSKNNQIRTVRRTDGKFFLSPDLNWDDFLFFCCCSQSKRKMLENPNEKSQIQKKPETLKSIFQKFPDTFDLIAIGLSYDTTENDLTDYLNRFGKLVYCKLKCDDVFGYSRGVAYFRFSGIKSQNLCLSATHVVDKTKIMIRIPNEKINIKE-RESSKLYVSNVCNTLTREDLRAYFHQFGHVIHVFLPPDKRNFAFVTFLHDKSIELVMKE 848
            Y+RV   +N E +E+P + D T+  + +++QFP + GL+YRN ++  +R VR  +G    +P+  W + ++     +  ++ +E  +  S ++     +K  FQK   T DLI +GL + TTE DL DY + FG+++  ++K D   G S+G  + RF+  ++Q   ++  H++D      ++PN K+   E   S K++V      +T ++LR YF Q+G V  VF+P   R FAFVTF  D+  + +  E
Sbjct:    5 YIRVAEDENEEPMEIPSEDDGTVLLSSVAAQFPGACGLRYRNPESQCMRGVRLVEG-VLHAPENEWGNLVYVVNYPKDNKRKMEEIDAASAVK-----VKRGFQK---TSDLIVLGLPWKTTEQDLKDYFSTFGEVIMVQVKRDAKTGNSKGFGFVRFADYETQTKVITQRHMIDGRWCDCKLPNSKVCPDEPMRSRKIFVGRCTEDMTPDELRQYFMQYGEVTDVFIPKPFRAFAFVTFADDQVAQALCGE 247          
BLAST of TAR DNA-binding protein 43 vs. Ensembl Medaka
Match: tardbpl (TAR DNA binding protein [Source:NCBI gene;Acc:101173545])

HSP 1 Score: 145.591 bits (366), Expect = 4.327e-39
Identity = 80/244 (32.79%), Postives = 137/244 (56.15%), Query Frame = 3
Query:   96 YVRVKGIDNLEIVELPLDLDNTLSFAVLSSQFPYSTGLKYRNSKNNQIRTVRRTDGKFFLSPDLNWDDFLFFCCCSQSKRKMLENPNEKSQIQKKPETLKSIFQKFPDTFDLIAIGLSYDTTENDLTDYLNRFGKLVYCKLKCDDVFGYSRGVAYFRFSGIKSQNLCLSATHVVDKTKIMIRIPNEKINIKE-RESSKLYVSNVCNTLTREDLRAYFHQFGHVIHVFLPPDKRNFAFVTFLHDK 824
            Y+RV   +N E +E+P + D T+  + +++QFP + GL+YRN ++  +R VR  +G    +P+  W + ++     +  ++ +E  +  S ++     +K  FQK   T DLI +GL + TTE DL DY + FG+++  ++K D   G S+G  + RF+  ++Q   ++  H++D      ++PN K+   E   S K++V      +T ++LR YF Q+G V  VF+P   R FAFVTF  D+
Sbjct:    5 YIRVAEDENEEPMEIPSEDDGTVLLSSVAAQFPGACGLRYRNPESQCMRGVRLVEG-VLHAPENEWGNLVYVVNYPKDNKRKMEEIDAASAVK-----VKRGFQK---TSDLIVLGLPWKTTEQDLKDYFSTFGEVIMVQVKRDAKTGNSKGFGFVRFADYETQTKVITQRHMIDGRWCDCKLPNSKVCPDEPMRSRKIFVGRCTEDMTPDELRQYFMQYGEVTDVFIPKPFRAFAFVTFADDQ 239          
BLAST of TAR DNA-binding protein 43 vs. Ensembl Medaka
Match: tardbp (TAR DNA-binding protein 43-like [Source:NCBI gene;Acc:101167445])

HSP 1 Score: 134.806 bits (338), Expect = 4.850e-34
Identity = 77/256 (30.08%), Postives = 137/256 (53.52%), Query Frame = 3
Query:   84 IENKYVRVKGIDNLEIVELPLDLDNTLSFAVLSSQFPYSTGLKYRNSKNNQIRTVRRTDGKFFLSPDLNWDDFLFFCCCSQSKRKMLENPNEKSQIQKKPETLKSIFQKFPDTFDLIAIGLSYDTTENDLTDYLNRFGKLVYCKLKCDDVFGYSRGVAYFRFSGIKSQNLCLSATHVVDKTKIMIRIPNEKINIKE-RESSKLYVSNVCNTLTREDLRAYFHQFGHVIHVFLPPDKRNFAFVTFLHDKSIELVMKE 848
            +   Y+RV   +N E +E+P + D T+  + +++QFP + GL++R+  +  +R VR  +G    +P+  W + ++     +  ++ ++  +  S ++ K   +K        T DLI +GL + TTE DL DY + FG+++  ++K D   G S+G  + RF+  ++Q   +S  H++D      ++PN K    E   S K++V      +T +DLR +F Q+G V  VF+P   R FAFVTF  D+  + +  E
Sbjct:    1 MAEGYIRVAEEENEEPMEIPSEDDGTVLLSTVAAQFPGACGLRFRSPVSQCMRGVRLVEG-VLHAPETGWGNVVYVVNYPKDNKRKMDEIDASSAVKMKRGDMK--------TSDLIVLGLPWKTTEQDLKDYFSTFGEVIMVQVKRDAKTGNSKGFGFVRFTEYEAQEKVISQRHMIDGRWCDCKLPNSKQGPDEPLRSRKVFVGRCTEDMTTDDLRQFFMQYGEVTDVFIPKPFRAFAFVTFADDQVAQSLCGE 247          
BLAST of TAR DNA-binding protein 43 vs. Ensembl Medaka
Match: hnrnpaba (heterogeneous nuclear ribonucleoprotein A/B [Source:NCBI gene;Acc:101162934])

HSP 1 Score: 83.5741 bits (205), Expect = 4.058e-17
Identity = 47/163 (28.83%), Postives = 83/163 (50.92%), Query Frame = 3
Query:  417 DTFDLIAIGLSYDTTENDLTDYLNRFGKLVYCKLKCDDVFGYSRGVAYFRFSGIKSQNLCLS-ATHVVDKTKIMIRIPNEKINIKERESSKLYVSNVCNTLTREDLRAYFHQFGHVIHVFLPPD-----KRNFAFVTFLHDKSIELVMKEGQTHCFNGARVNV 887
            D   +   GLS+DT++ DL DY ++FG++  C +K D   G SRG  +  F    S +  L    H +D  +I    P   + +K+    K++V  +   L++E++  YF  FG +  + LP D     +R F F+T+  + S++ V+ E + H   G++  +
Sbjct:   70 DAGKMFVGGLSWDTSKKDLKDYFSKFGEVTDCTIKMDQQTGRSRGFGFILFKDAASVDKVLEQKEHRLDGRQI---DPKRAMAMKKEIVKKIFVGGLKPDLSKEEIEEYFGAFGEIETIELPQDPKTEKRRGFVFITYKEEPSVKKVL-EKKYHTVGGSKCEI 228          
BLAST of TAR DNA-binding protein 43 vs. Ensembl Medaka
Match: hnrnpaba (heterogeneous nuclear ribonucleoprotein A/B [Source:NCBI gene;Acc:101162934])

HSP 1 Score: 83.5741 bits (205), Expect = 5.009e-17
Identity = 47/163 (28.83%), Postives = 83/163 (50.92%), Query Frame = 3
Query:  417 DTFDLIAIGLSYDTTENDLTDYLNRFGKLVYCKLKCDDVFGYSRGVAYFRFSGIKSQNLCLS-ATHVVDKTKIMIRIPNEKINIKERESSKLYVSNVCNTLTREDLRAYFHQFGHVIHVFLPPD-----KRNFAFVTFLHDKSIELVMKEGQTHCFNGARVNV 887
            D   +   GLS+DT++ DL DY ++FG++  C +K D   G SRG  +  F    S +  L    H +D  +I    P   + +K+    K++V  +   L++E++  YF  FG +  + LP D     +R F F+T+  + S++ V+ E + H   G++  +
Sbjct:   85 DAGKMFVGGLSWDTSKKDLKDYFSKFGEVTDCTIKMDQQTGRSRGFGFILFKDAASVDKVLEQKEHRLDGRQI---DPKRAMAMKKEIVKKIFVGGLKPDLSKEEIEEYFGAFGEIETIELPQDPKTEKRRGFVFITYKEEPSVKKVL-EKKYHTVGGSKCEI 243          
BLAST of TAR DNA-binding protein 43 vs. Planmine SMEST
Match: SMESG000042285.1 (SMESG000042285.1)

HSP 1 Score: 870.152 bits (2247), Expect = 0.000e+0
Identity = 448/448 (100.00%), Postives = 448/448 (100.00%), Query Frame = 3
Query:   81 MIENKYVRVKGIDNLEIVELPLDLDNTLSFAVLSSQFPYSTGLKYRNSKNNQIRTVRRTDGKFFLSPDLNWDDFLFFCCCSQSKRKMLENPNEKSQIQKKPETLKSIFQKFPDTFDLIAIGLSYDTTENDLTDYLNRFGKLVYCKLKCDDVFGYSRGVAYFRFSGIKSQNLCLSATHVVDKTKIMIRIPNEKINIKERESSKLYVSNVCNTLTREDLRAYFHQFGHVIHVFLPPDKRNFAFVTFLHDKSIELVMKEGQTHCFNGARVNVYRVMEKDLLTNINCPQQLKHKDSCRKRKQSTEKQDYLNQSSISKLNQNVHFINSPEGSKNTFPSSQINSYSNIHTNSQLXXXXXXXXXXXXXXXXXXXXXXXHITRFIQSYADQSVSQTIQNLSPNSSKSHISNQTSPGLIQPLNQGFQPNFNKESFLSEIRHSKPDSFQSLVIKEILE 1424
            MIENKYVRVKGIDNLEIVELPLDLDNTLSFAVLSSQFPYSTGLKYRNSKNNQIRTVRRTDGKFFLSPDLNWDDFLFFCCCSQSKRKMLENPNEKSQIQKKPETLKSIFQKFPDTFDLIAIGLSYDTTENDLTDYLNRFGKLVYCKLKCDDVFGYSRGVAYFRFSGIKSQNLCLSATHVVDKTKIMIRIPNEKINIKERESSKLYVSNVCNTLTREDLRAYFHQFGHVIHVFLPPDKRNFAFVTFLHDKSIELVMKEGQTHCFNGARVNVYRVMEKDLLTNINCPQQLKHKDSCRKRKQSTEKQDYLNQSSISKLNQNVHFINSPEGSKNTFPSSQINSYSNIHTNSQLPPIAFPPYNFPPPPFSTPSKSVSHITRFIQSYADQSVSQTIQNLSPNSSKSHISNQTSPGLIQPLNQGFQPNFNKESFLSEIRHSKPDSFQSLVIKEILE
Sbjct:    1 MIENKYVRVKGIDNLEIVELPLDLDNTLSFAVLSSQFPYSTGLKYRNSKNNQIRTVRRTDGKFFLSPDLNWDDFLFFCCCSQSKRKMLENPNEKSQIQKKPETLKSIFQKFPDTFDLIAIGLSYDTTENDLTDYLNRFGKLVYCKLKCDDVFGYSRGVAYFRFSGIKSQNLCLSATHVVDKTKIMIRIPNEKINIKERESSKLYVSNVCNTLTREDLRAYFHQFGHVIHVFLPPDKRNFAFVTFLHDKSIELVMKEGQTHCFNGARVNVYRVMEKDLLTNINCPQQLKHKDSCRKRKQSTEKQDYLNQSSISKLNQNVHFINSPEGSKNTFPSSQINSYSNIHTNSQLPPIAFPPYNFPPPPFSTPSKSVSHITRFIQSYADQSVSQTIQNLSPNSSKSHISNQTSPGLIQPLNQGFQPNFNKESFLSEIRHSKPDSFQSLVIKEILE 448          
BLAST of TAR DNA-binding protein 43 vs. Planmine SMEST
Match: SMESG000032661.1 (SMESG000032661.1)

HSP 1 Score: 147.902 bits (372), Expect = 2.229e-38
Identity = 87/273 (31.87%), Postives = 143/273 (52.38%), Query Frame = 3
Query:   96 YVRVKGIDNLEIVELPLDLDNTLSFAVLSSQFPYSTGLKYRNSKNNQIRTVRRTDGKFFLSPDLNWDDFLFFCCCSQ--SKRKMLENPNEKSQIQKKPETLKSIFQKFPDTFDLIAIGLSYDTTENDLTDYLNRFGKLVYCKLKCDDVFGYSRGVAYFRFSGIKSQNLCLSATHVVDKTKIMIRIPNEKINIKERE-SSKLYVSNVCNTLTREDLRAYFHQFGHVIHVFLPPDKRNFAFVTFLHDKSIELVMKEGQTHCFNGARVNVYRVMEK 905
            Y+ V   +  E +E+P++ D+T+    L   FP   GLKYR  + N  R ++ +DGKF+  P   W+D  F+C   +  +KRK+ E   +  Q  K+ E  K          DLI + L +   E  L  Y ++FG+LV  ++K D    +S+G A+ RF+   +Q LCL+  H++D     +++P  K    ++E S K++V      ++ EDLR  F Q+G+V  +F+P   RNFAFVTF    + + ++  GQ+   NG  + +   + K
Sbjct:    3 YIAVCEYEESETIEIPVEEDDTVLLTTLGGIFPNVCGLKYRAPETNTFRALKLSDGKFY-KPVEGWEDLKFYCVFPKDNNKRKIDEEIEKPLQKSKRLEGRKCT--------DLIVLNLGWKVDEETLRKYFSKFGELVLVQVKKDRETSHSKGYAFIRFADYAAQVLCLAEKHLIDGRWCAVKVPFSKNEADKQEISKKIHVGYASEEISMEDLRIAFEQYGYVTDIFIPKPFRNFAFVTFDSSDTAQSLI--GQSININGITLTIGSAVPK 264          
BLAST of TAR DNA-binding protein 43 vs. Planmine SMEST
Match: SMESG000048176.1 (SMESG000048176.1)

HSP 1 Score: 141.739 bits (356), Expect = 1.981e-35
Identity = 82/271 (30.26%), Postives = 138/271 (50.92%), Query Frame = 3
Query:   96 YVRVKGIDNLEIVELPLDLDNTLSFAVLSSQFPYSTGLKYRNSKNNQIRTVRRTDGKFFLSPDLNWDDFLFFCCCSQSKRKMLENPNEKSQIQKKPETLKSIFQKFP-DTFDLIAIGLSYDTTENDLTDYLNRFGKLVYCKLKCDDVFGYSRGVAYFRFSGIKSQNLCLSATHVVDKTKIMIRIPNEKINIKERESSKLYVSNVCNTLTREDLRAYFHQFGHVIHVFLPPDKRNFAFVTFLHDKSIELVMKEGQTHCFNGARVNVYRVMEK 905
            + +V   +N   VE+P + D +L  + L   F    G++YR      +R     D +  L   + W D +F C   ++ +K LENPN             S+ +KF   TFD+IA+GL  D T+     Y ++FGKL  C+L+ +     S+G  + R+     Q+ C+   HV+  T + +R+P  K++       KL+V+N+  ++T+E +  YF+ FG ++ +F+PP     AF+TF  ++SI  + + G++H   G  V V RV  K
Sbjct:    2 FAKVASTENSNYVEIPTNEDGSLRISELRKYFVNCVGIRYRCKSTGNLRGTWVFDDQLQLPLGVTWSDNVFHCVYEETGKK-LENPNSNVN--------NSLSEKFQLKTFDMIALGLPDDITDESFYRYFSKFGKLKMCELRKNLKKPKSKGYGFLRYVNFDDQSECIRTEHVIGNTTVCLRLPTAKMD-SSTCKRKLFVTNITPSVTQEHILEYFNVFGKIVEIFMPPASNPHAFLTFEAEESILRIFRFGESHRVFGGYVVVERVYTK 262          
BLAST of TAR DNA-binding protein 43 vs. Planmine SMEST
Match: SMESG000032660.1 (SMESG000032660.1)

HSP 1 Score: 135.191 bits (339), Expect = 2.202e-35
Identity = 80/231 (34.63%), Postives = 122/231 (52.81%), Query Frame = 3
Query:  132 VELPLDLDNTLSFAVLSSQFPYSTGLKYRNSKNNQIRTVRRTDGKFFLSPDLNWDDFLFFCCCSQS---KRKMLENPNEKSQIQKKPETLKSIFQKFPDTFDLIAIGLSYDTTENDLTDYLNRFGKLVYCKLKCDDVFGYSRGVAYFRFSGIKSQNLCLSATHVVDKTKIMIRIPNEKINIKERE-SSKLYVSNVCNTLTREDLRAYFHQFGHVIHVFLPPDKRNFAFVTF 812
            VE+PL+ D+T+ F  LS QFP  +GLKYR S +   R ++ ++GK F  P   W      C   +    KRK  E     +   K+ +T K          DLI + L +   E  L +Y ++FG LV  ++K D    +S+G A+ RF+    Q LCL+  H++D     +++P  K    ++E + K++VS     L  EDLR  F ++G+V+ +F+P   RNFAFVTF
Sbjct:   15 VEIPLEEDDTILFTTLSGQFPKVSGLKYRFSGSLNFRAIKLSEGKLF-KPLEGWGSLKLICVFPKEIDNKRKCKEEYEIPTPKTKRLDTRKCT--------DLIVLNLGWKVDEEMLRNYFSKFGDLVLVQIKKDRETNHSKGYAFVRFADYDGQVLCLAEQHLIDGRWCSVKVPFSKSEADKQEITKKIHVSYSAEELEMEDLRKAFEEYGYVVDIFIPKPFRNFAFVTF 236          
BLAST of TAR DNA-binding protein 43 vs. Planmine SMEST
Match: SMESG000032660.1 (SMESG000032660.1)

HSP 1 Score: 137.502 bits (345), Expect = 7.211e-35
Identity = 80/231 (34.63%), Postives = 123/231 (53.25%), Query Frame = 3
Query:  132 VELPLDLDNTLSFAVLSSQFPYSTGLKYRNSKNNQIRTVRRTDGKFFLSPDLNWDDFLFFCCCSQ---SKRKMLENPNEKSQIQKKPETLKSIFQKFPDTFDLIAIGLSYDTTENDLTDYLNRFGKLVYCKLKCDDVFGYSRGVAYFRFSGIKSQNLCLSATHVVDKTKIMIRIPNEKINIKERE-SSKLYVSNVCNTLTREDLRAYFHQFGHVIHVFLPPDKRNFAFVTF 812
            VE+PL+ D+T+ F  LS QFP  +GLKYR S +   R ++ ++GK F  P   W      C   +   +KRK  E     +   K+ +T K          DLI + L +   E  L +Y ++FG LV  ++K D    +S+G A+ RF+    Q LCL+  H++D     +++P  K    ++E + K++VS     L  EDLR  F ++G+V+ +F+P   RNFAFVTF
Sbjct:   15 VEIPLEEDDTILFTTLSGQFPKVSGLKYRFSGSLNFRAIKLSEGKLF-KPLEGWGSLKLICVFPKEIDNKRKCKEEYEIPTPKTKRLDTRKCT--------DLIVLNLGWKVDEEMLRNYFSKFGDLVLVQIKKDRETNHSKGYAFVRFADYDGQVLCLAEQHLIDGRWCSVKVPFSKSEADKQEITKKIHVSYSAEELEMEDLRKAFEEYGYVVDIFIPKPFRNFAFVTF 236          
The following BLAST results are available for this feature:
BLAST of TAR DNA-binding protein 43 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
TARDBP6.792e-3831.71TAR DNA binding protein [Source:HGNC Symbol;Acc:HG... [more]
TARDBP7.529e-3831.71TAR DNA binding protein [Source:HGNC Symbol;Acc:HG... [more]
TARDBP7.529e-3831.71TAR DNA binding protein [Source:HGNC Symbol;Acc:HG... [more]
AL109811.37.529e-3831.71novel protein[more]
TARDBP8.403e-3831.71TAR DNA binding protein [Source:HGNC Symbol;Acc:HG... [more]
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BLAST of TAR DNA-binding protein 43 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
tdp-11.610e-2024.74Tar DNA-binding protein homolog 1 [Source:UniProt... [more]
tdp-16.374e-2024.41Tar DNA-binding protein homolog 1 [Source:UniProt... [more]
sqd-19.587e-1430.00Homologous to Drosophila SQD (Squid) protein [Sou... [more]
sqd-19.587e-1430.00Homologous to Drosophila SQD (Squid) protein [Sou... [more]
sqd-19.587e-1430.00Homologous to Drosophila SQD (Squid) protein [Sou... [more]
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BLAST of TAR DNA-binding protein 43 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
CG78044.924e-4232.60gene:FBgn0036496 transcript:FBtr0332815[more]
CG78044.924e-4232.60gene:FBgn0036496 transcript:FBtr0075617[more]
TBPH2.004e-3832.23gene:FBgn0025790 transcript:FBtr0089626[more]
TBPH5.042e-3732.23gene:FBgn0025790 transcript:FBtr0089625[more]
TBPH5.042e-3732.23gene:FBgn0025790 transcript:FBtr0089624[more]
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BLAST of TAR DNA-binding protein 43 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
tardbpl1.484e-3730.45TAR DNA binding protein, like [Source:ZFIN;Acc:ZDB... [more]
tardbpl1.484e-3730.45TAR DNA binding protein, like [Source:ZFIN;Acc:ZDB... [more]
tardbpl1.484e-3730.45TAR DNA binding protein, like [Source:ZFIN;Acc:ZDB... [more]
tardbpl1.924e-3629.52TAR DNA binding protein, like [Source:ZFIN;Acc:ZDB... [more]
tardbpl1.924e-3629.52TAR DNA binding protein, like [Source:ZFIN;Acc:ZDB... [more]
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BLAST of TAR DNA-binding protein 43 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
jarid23.650e-4030.98jumonji and AT-rich interaction domain containing ... [more]
jarid23.151e-2629.69jumonji and AT-rich interaction domain containing ... [more]
h2bc212.449e-1532.00H2B clustered histone 21 [Source:Xenbase;Acc:XB-GE... [more]
h2bc212.634e-1532.00H2B clustered histone 21 [Source:Xenbase;Acc:XB-GE... [more]
h2bc213.705e-1532.00H2B clustered histone 21 [Source:Xenbase;Acc:XB-GE... [more]
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BLAST of TAR DNA-binding protein 43 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Tardbp3.269e-3931.89TAR DNA binding protein [Source:MGI Symbol;Acc:MGI... [more]
Tardbp6.537e-3931.89TAR DNA binding protein [Source:MGI Symbol;Acc:MGI... [more]
Tardbp6.537e-3931.89TAR DNA binding protein [Source:MGI Symbol;Acc:MGI... [more]
Tardbp6.537e-3931.89TAR DNA binding protein [Source:MGI Symbol;Acc:MGI... [more]
Tardbp6.537e-3931.89TAR DNA binding protein [Source:MGI Symbol;Acc:MGI... [more]
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BLAST of TAR DNA-binding protein 43 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q28F51|TADBP_XENTR1.426e-3930.98TAR DNA-binding protein 43 OS=Xenopus tropicalis O... [more]
sp|Q921F2|TADBP_MOUSE7.964e-3831.89TAR DNA-binding protein 43 OS=Mus musculus OX=1009... [more]
sp|Q13148|TADBP_HUMAN1.004e-3631.71TAR DNA-binding protein 43 OS=Homo sapiens OX=9606... [more]
sp|Q5R5W2|TADBP_PONAB5.018e-3631.30TAR DNA-binding protein 43 OS=Pongo abelii OX=9601... [more]
sp|Q5ZLN5|TADBP_CHICK6.653e-3529.92TAR DNA-binding protein 43 OS=Gallus gallus OX=903... [more]
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BLAST of TAR DNA-binding protein 43 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A2T7PUB67.104e-4435.66Uncharacterized protein OS=Pomacea canaliculata OX... [more]
R7TFC36.960e-4335.51Uncharacterized protein OS=Capitella teleta OX=283... [more]
A0A0L7KS514.631e-4235.71TAR DNA-binding protein 43 OS=Operophtera brumata ... [more]
A0A0K8TR165.565e-4235.64Putative rna-binding protein musashi/mrna cleavage... [more]
A0A087TT601.769e-4134.53TAR DNA-binding protein 43 (Fragment) OS=Stegodyph... [more]
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BLAST of TAR DNA-binding protein 43 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
tardbpl6.293e-3729.89TAR DNA binding protein [Source:NCBI gene;Acc:1030... [more]
tardbpl1.501e-3630.00TAR DNA binding protein [Source:NCBI gene;Acc:1030... [more]
tardbp3.288e-3232.40TAR DNA-binding protein 43-like [Source:NCBI gene;... [more]
hnrnpabb1.564e-1829.45heterogeneous nuclear ribonucleoprotein A/B [Sourc... [more]
hnrnpabb1.566e-1829.45heterogeneous nuclear ribonucleoprotein A/B [Sourc... [more]
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BLAST of TAR DNA-binding protein 43 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSPMAT00000009806.14.073e-3629.68pep scaffold:Pmarinus_7.0:GL479354:9188:12030:-1 g... [more]
TARDBP1.008e-2136.31TAR DNA binding protein [Source:HGNC Symbol;Acc:HG... [more]
ENSPMAT00000004893.11.053e-1127.96pep scaffold:Pmarinus_7.0:GL479484:4:2056:-1 gene:... [more]
HNRNPA2B11.271e-1129.27heterogeneous nuclear ribonucleoprotein A2/B1 [Sou... [more]
ENSPMAT00000007723.12.150e-928.43pep scaffold:Pmarinus_7.0:GL496487:1152:2091:-1 ge... [more]
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BLAST of TAR DNA-binding protein 43 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1
Match NameE-valueIdentityDescription
HRP16.314e-1227.34Subunit of cleavage factor I; cleavage factor I is... [more]
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BLAST of TAR DNA-binding protein 43 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO449405.272e-3631.48Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO398792.785e-1427.81Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO493496.208e-1332.67Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO384177.661e-926.01Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO392236.589e-634.55Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of TAR DNA-binding protein 43 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
tardbpl9.419e-4032.14TAR DNA binding protein [Source:NCBI gene;Acc:1011... [more]
tardbpl4.327e-3932.79TAR DNA binding protein [Source:NCBI gene;Acc:1011... [more]
tardbp4.850e-3430.08TAR DNA-binding protein 43-like [Source:NCBI gene;... [more]
hnrnpaba4.058e-1728.83heterogeneous nuclear ribonucleoprotein A/B [Sourc... [more]
hnrnpaba5.009e-1728.83heterogeneous nuclear ribonucleoprotein A/B [Sourc... [more]
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BLAST of TAR DNA-binding protein 43 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000042285.10.000e+0100.00SMESG000042285.1[more]
SMESG000032661.12.229e-3831.87SMESG000032661.1[more]
SMESG000048176.11.981e-3530.26SMESG000048176.1[more]
SMESG000032660.12.202e-3534.63SMESG000032660.1[more]
SMESG000032660.17.211e-3534.63SMESG000032660.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30018423 ID=SMED30018423|Name=TAR DNA-binding protein 43|organism=Schmidtea mediterranea sexual|type=transcript|length=1901bp
TTATAATAGGCACCAATTTAAATATCAAATTTAAGAAATAAAATAAATTG
AACAAGAGTAATTGATTCAATAAATAAGAAATGATTGAAAATAAATATGT
AAGAGTTAAAGGAATAGATAATTTAGAAATCGTGGAATTGCCATTAGATC
TCGATAATACTTTATCTTTCGCAGTTCTTTCATCCCAATTTCCATATTCG
ACAGGATTAAAGTATAGGAATTCGAAAAATAATCAAATCCGAACAGTTCG
ACGAACAGATGGAAAATTTTTCCTATCACCAGATTTAAATTGGGATGATT
TTTTATTCTTTTGCTGTTGTTCACAAAGCAAACGAAAAATGCTGGAAAAT
CCAAACGAGAAATCTCAGATACAAAAAAAACCAGAAACACTGAAATCAAT
TTTTCAGAAATTTCCGGACACATTTGATCTGATAGCTATTGGATTATCCT
ATGATACAACTGAAAACGATTTGACTGACTATTTAAATCGGTTTGGGAAA
TTAGTTTATTGCAAATTGAAATGCGATGATGTTTTCGGCTATAGTCGTGG
AGTGGCGTATTTTCGATTCAGTGGCATAAAATCTCAAAATCTCTGCTTGA
GTGCAACCCATGTTGTTGACAAAACGAAAATTATGATCAGAATTCCAAAC
GAAAAAATTAATATCAAAGAAAGAGAATCCAGTAAATTGTATGTCAGCAA
TGTCTGTAATACTCTCACGAGAGAAGATCTTCGGGCTTATTTTCATCAAT
TTGGACATGTGATTCACGTTTTCTTGCCACCAGATAAGCGTAATTTTGCA
TTTGTCACCTTTCTACATGACAAATCAATTGAACTTGTTATGAAAGAAGG
TCAAACTCATTGTTTTAATGGTGCTCGCGTAAATGTGTATCGAGTTATGG
AAAAAGATCTGCTCACAAATATTAACTGTCCACAGCAACTCAAACATAAA
GATAGTTGTCGAAAAAGAAAGCAATCAACTGAAAAGCAAGATTATTTAAA
TCAGTCCTCGATCTCTAAACTAAATCAAAATGTTCACTTTATCAACAGTC
CAGAAGGTTCGAAAAATACGTTTCCGTCTAGTCAAATTAATTCATATTCG
AATATACATACTAACAGCCAATTGCCTCCAATTGCATTTCCGCCATATAA
TTTCCCCCCTCCTCCTTTTTCTACACCCTCTAAATCAGTTTCTCATATAA
CTCGATTTATACAGTCATATGCAGATCAATCAGTATCACAAACTATACAG
AATTTATCACCGAACTCAAGCAAGTCCCATATTTCTAATCAGACTTCACC
AGGTTTAATTCAACCTTTAAATCAAGGATTTCAACCAAATTTCAACAAAG
AATCATTTTTATCAGAGATTAGACATTCAAAGCCAGATTCATTTCAGTCC
CTCGTTATTAAGGAGATACTTGAAAAATTTCACCAACAAAAATCTCAGCA
ATATCAGTCATTCCAACAATCAGAAAAATTTATCTCTGAATTGAACAAAA
ACGTCTCAGCGGAAAATTCCGTTAAAAATTGCAGTCAATGGGAAAATCTA
GTCAGCAAGGTACGCTTATTGCAAAAACAAAGTTCCCAATTGAAAAATGA
AGAATATTCAATTCAAACTTTATTAAATTTTCAAAAGTCTGAACTAAAGT
TTAAACCAGATAATGTTGATTTAACAGTGCTTAATGATCCTAAGATCCAT
AAAGCAATGAAAGTGTTAAAAGATTCCAGAGTATTAAATTTGTTGTTGCG
ATTATCACAAAGTGACATGGAACATTGTATTTCTAACTTTTAACTAACTC
CTTTGAACATTGGATAATTGTTTTAATACTGATGTTTTCATCTATGAAGC
GTAAAAGTCATTGCAAAAATCATGAAGAAACTATTATTCATATAATTTAA
T
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protein sequence of SMED30018423-orf-1

>SMED30018423-orf-1 ID=SMED30018423-orf-1|Name=SMED30018423-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=571bp
MIENKYVRVKGIDNLEIVELPLDLDNTLSFAVLSSQFPYSTGLKYRNSKN
NQIRTVRRTDGKFFLSPDLNWDDFLFFCCCSQSKRKMLENPNEKSQIQKK
PETLKSIFQKFPDTFDLIAIGLSYDTTENDLTDYLNRFGKLVYCKLKCDD
VFGYSRGVAYFRFSGIKSQNLCLSATHVVDKTKIMIRIPNEKINIKERES
SKLYVSNVCNTLTREDLRAYFHQFGHVIHVFLPPDKRNFAFVTFLHDKSI
ELVMKEGQTHCFNGARVNVYRVMEKDLLTNINCPQQLKHKDSCRKRKQST
EKQDYLNQSSISKLNQNVHFINSPEGSKNTFPSSQINSYSNIHTNSQLPP
IAFPPYNFPPPPFSTPSKSVSHITRFIQSYADQSVSQTIQNLSPNSSKSH
ISNQTSPGLIQPLNQGFQPNFNKESFLSEIRHSKPDSFQSLVIKEILEKF
HQQKSQQYQSFQQSEKFISELNKNVSAENSVKNCSQWENLVSKVRLLQKQ
SSQLKNEEYSIQTLLNFQKSELKFKPDNVDLTVLNDPKIHKAMKVLKDSR
VLNLLLRLSQSDMEHCISNF*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: molecular function
TermDefinition
GO:0003723RNA binding
GO:0003676nucleic acid binding
GO:0000166nucleotide binding
GO:0003677DNA binding
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000020protonephridia
PLANA:0000099neuron
Vocabulary: INTERPRO
TermDefinition
IPR041105TDP43_N
IPR035979RBD_domain_sf
IPR000504RRM_dom
IPR012677Nucleotide-bd_a/b_plait_sf
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000504RNA recognition motif domainSMARTSM00360rrm1_1coord: 202..270
e-value: 3.1E-11
score: 53.3
coord: 116..187
e-value: 1.8E-4
score: 30.8
IPR000504RNA recognition motif domainPFAMPF00076RRM_1coord: 121..172
e-value: 1.6E-5
score: 24.6
coord: 203..266
e-value: 2.1E-9
score: 37.1
IPR000504RNA recognition motif domainPROSITEPS50102RRMcoord: 201..274
score: 12.492
IPR000504RNA recognition motif domainPROSITEPS50102RRMcoord: 115..200
score: 10.07
IPR041105TAR DNA-binding protein 43, N-terminalPFAMPF18694TDP43_Ncoord: 6..79
e-value: 8.0E-18
score: 64.1
IPR012677Nucleotide-binding alpha-beta plait domain superfamilyGENE3DG3DSA:3.30.70.330coord: 80..193
e-value: 6.9E-9
score: 37.8
IPR012677Nucleotide-binding alpha-beta plait domain superfamilyGENE3DG3DSA:3.30.70.330coord: 194..277
e-value: 4.5E-16
score: 60.6
NoneNo IPR availablePANTHERPTHR23147SERINE/ARGININE RICH SPLICING FACTORcoord: 4..248
NoneNo IPR availablePANTHERPTHR23147:SF103TAR DNA-BINDING PROTEIN 43coord: 4..248
IPR035979RNA-binding domain superfamilySUPERFAMILYSSF54928RNA-binding domain, RBDcoord: 187..277
IPR035979RNA-binding domain superfamilySUPERFAMILYSSF54928RNA-binding domain, RBDcoord: 111..188