TPA_inf: Pax-beta1 paired domain protein

Overview
NameTPA_inf: Pax-beta1 paired domain protein (DAA12513.1)
Smed IDSMED30018397
Length (bp)2122
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of TPA_inf: Pax-beta1 paired domain protein (SMED30018397) t-SNE clustered cells

Violin plots show distribution of expression levels for TPA_inf: Pax-beta1 paired domain protein (SMED30018397) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of TPA_inf: Pax-beta1 paired domain protein (SMED30018397) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for TPA_inf: Pax-beta1 paired domain protein (SMED30018397) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30018397

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 7

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
prepharyngeal regionSMED30018397h1SMcG0012750 SmedASXL_014957SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016
whole organism asexual adult RNA-sequencing evidence
parapharyngeal regionSMED30018397h1SMcG0012750 SmedASXL_014957SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016
whole organism asexual adult RNA-sequencing evidence
pharynxSMED30018397h1SMcG0012750 dd_Smed_v4_15732_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
nervous systemSMED30018397h1SMcG0012750 dd_Smed_v4_15732_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30018397h1SMcG0012750 dd_Smed_v4_15732_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cilated neuronSMED30018397h1SMcG0012750 dd_Smed_v4_15732_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parapharyngeal regionSMED30018397h1SMcG0012750 dd_Smed_v6_15732_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017
whole organism asexual adult RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of TPA_inf: Pax-beta1 paired domain protein vs. Ensembl Human
Match: PAX5 (paired box 5 [Source:HGNC Symbol;Acc:HGNC:8619])

HSP 1 Score: 176.407 bits (446), Expect = 2.281e-49
Identity = 90/171 (52.63%), Postives = 115/171 (67.25%), Query Frame = 3
Query:  618 QSERAGAGQNVNQYGRVFTNGRPLPEDLRLKILKMAMENVRPCEISRQLQVSHGCVSKILNRYSRTGSINPGQIGGSKPKVTTPEIVSLVKSYREKNPQIFAWEIRQRLVDEGACTERSAPSISSINRIIRDK-------GIKTSSVGRIDEGDIKQLESLSAHSDGSVMS 1109
            ++ R G G  VNQ G VF NGRPLP+ +R +I+++A + VRPC+ISRQL+VSHGCVSKIL RY  TGSI PG IGGSKPKV TP++V  +  Y+ +NP +FAWEIR RL+ E  C   + PS+SSINRIIR K        +  SS   +  G + Q+ S+S  S GS  S
Sbjct:   11 RTSRTGHG-GVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVEKIAEYKRQNPTMFAWEIRDRLLAERVCDNDTVPSVSSINRIIRTKVQQPPNQPVPASSHSIVSTGSVTQVSSVSTDSAGSSYS 180          
BLAST of TPA_inf: Pax-beta1 paired domain protein vs. Ensembl Human
Match: PAX5 (paired box 5 [Source:HGNC Symbol;Acc:HGNC:8619])

HSP 1 Score: 176.407 bits (446), Expect = 2.285e-49
Identity = 90/171 (52.63%), Postives = 115/171 (67.25%), Query Frame = 3
Query:  618 QSERAGAGQNVNQYGRVFTNGRPLPEDLRLKILKMAMENVRPCEISRQLQVSHGCVSKILNRYSRTGSINPGQIGGSKPKVTTPEIVSLVKSYREKNPQIFAWEIRQRLVDEGACTERSAPSISSINRIIRDK-------GIKTSSVGRIDEGDIKQLESLSAHSDGSVMS 1109
            ++ R G G  VNQ G VF NGRPLP+ +R +I+++A + VRPC+ISRQL+VSHGCVSKIL RY  TGSI PG IGGSKPKV TP++V  +  Y+ +NP +FAWEIR RL+ E  C   + PS+SSINRIIR K        +  SS   +  G + Q+ S+S  S GS  S
Sbjct:   11 RTSRTGHG-GVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVEKIAEYKRQNPTMFAWEIRDRLLAERVCDNDTVPSVSSINRIIRTKVQQPPNQPVPASSHSIVSTGSVTQVSSVSTDSAGSSYS 180          
BLAST of TPA_inf: Pax-beta1 paired domain protein vs. Ensembl Human
Match: PAX5 (paired box 5 [Source:HGNC Symbol;Acc:HGNC:8619])

HSP 1 Score: 177.178 bits (448), Expect = 3.000e-49
Identity = 90/171 (52.63%), Postives = 115/171 (67.25%), Query Frame = 3
Query:  618 QSERAGAGQNVNQYGRVFTNGRPLPEDLRLKILKMAMENVRPCEISRQLQVSHGCVSKILNRYSRTGSINPGQIGGSKPKVTTPEIVSLVKSYREKNPQIFAWEIRQRLVDEGACTERSAPSISSINRIIRDK-------GIKTSSVGRIDEGDIKQLESLSAHSDGSVMS 1109
            ++ R G G  VNQ G VF NGRPLP+ +R +I+++A + VRPC+ISRQL+VSHGCVSKIL RY  TGSI PG IGGSKPKV TP++V  +  Y+ +NP +FAWEIR RL+ E  C   + PS+SSINRIIR K        +  SS   +  G + Q+ S+S  S GS  S
Sbjct:   11 RTSRTGHG-GVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVEKIAEYKRQNPTMFAWEIRDRLLAERVCDNDTVPSVSSINRIIRTKVQQPPNQPVPASSHSIVSTGSVTQVSSVSTDSAGSSYS 180          
BLAST of TPA_inf: Pax-beta1 paired domain protein vs. Ensembl Human
Match: PAX5 (paired box 5 [Source:HGNC Symbol;Acc:HGNC:8619])

HSP 1 Score: 176.792 bits (447), Expect = 4.000e-49
Identity = 100/217 (46.08%), Postives = 126/217 (58.06%), Query Frame = 3
Query:  618 QSERAGAGQNVNQYGRVFTNGRPLPEDLRLKILKMAMENVRPCEISRQLQVSHGCVSKILNRYSRTGSINPGQIGGSKPKVTTPEIVSLVKSYREKNPQIFAWEIRQRLVDEGACTERSAPSISSINRIIRDK-------GIKTSSVGRIDEGDIKQLESLSAHSDGSVMS--------------NNNSSDRMLNESDSTKQHSEIVDTNLVKQERN 1205
            ++ R G G  VNQ G VF NGRPLP+ +R +I+++A + VRPC+ISRQL+VSHGCVSKIL RY  TGSI PG IGGSKPKV TP++V  +  Y+ +NP +FAWEIR RL+ E  C   + PS+SSINRIIR K        +  SS   +  G + Q+ S+S  S GS  S              N    D  + ES     HS      L KQ R 
Sbjct:   11 RTSRTGHG-GVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVEKIAEYKRQNPTMFAWEIRDRLLAERVCDNDTVPSVSSINRIIRTKVQQPPNQPVPASSHSIVSTGSVTQVSSVSTDSAGSSYSISGILGITSPSADTNKRKRDEGIQESPVPNGHSLPGRDFLRKQMRG 226          
BLAST of TPA_inf: Pax-beta1 paired domain protein vs. Ensembl Human
Match: PAX5 (paired box 5 [Source:HGNC Symbol;Acc:HGNC:8619])

HSP 1 Score: 176.022 bits (445), Expect = 4.994e-49
Identity = 90/171 (52.63%), Postives = 115/171 (67.25%), Query Frame = 3
Query:  618 QSERAGAGQNVNQYGRVFTNGRPLPEDLRLKILKMAMENVRPCEISRQLQVSHGCVSKILNRYSRTGSINPGQIGGSKPKVTTPEIVSLVKSYREKNPQIFAWEIRQRLVDEGACTERSAPSISSINRIIRDK-------GIKTSSVGRIDEGDIKQLESLSAHSDGSVMS 1109
            ++ R G G  VNQ G VF NGRPLP+ +R +I+++A + VRPC+ISRQL+VSHGCVSKIL RY  TGSI PG IGGSKPKV TP++V  +  Y+ +NP +FAWEIR RL+ E  C   + PS+SSINRIIR K        +  SS   +  G + Q+ S+S  S GS  S
Sbjct:   11 RTSRTGHG-GVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVEKIAEYKRQNPTMFAWEIRDRLLAERVCDNDTVPSVSSINRIIRTKVQQPPNQPVPASSHSIVSTGSVTQVSSVSTDSAGSSYS 180          
BLAST of TPA_inf: Pax-beta1 paired domain protein vs. Ensembl Celegans
Match: pax-2 (PAX (Paired box) transcription factor [Source:UniProtKB/TrEMBL;Acc:U4PCL3])

HSP 1 Score: 172.555 bits (436), Expect = 1.982e-48
Identity = 75/130 (57.69%), Postives = 97/130 (74.62%), Query Frame = 3
Query:  633 GAGQNVNQYGRVFTNGRPLPEDLRLKILKMAMENVRPCEISRQLQVSHGCVSKILNRYSRTGSINPGQIGGSKPKVTTPEIVSLVKSYREKNPQIFAWEIRQRLVDEGACTERSAPSISSINRIIRDKGI 1022
            G+   VNQ G VF NGRPLP+ +R +I++M+    RPC+ISRQL+VSHGCVSKIL RY  TGS+ PG IGGSKPKV TP +V  +  Y+  NP +FAWEIRQ+L+++  C E + PS+SSINRI+R+K  
Sbjct:   28 GSHTGVNQLGGVFVNGRPLPDTIRAQIVEMSQHGTRPCDISRQLKVSHGCVSKILGRYYSTGSVRPGVIGGSKPKVATPRVVECIAGYKRANPTMFAWEIRQKLIEDQICGEENVPSVSSINRIVRNKSF 157          
BLAST of TPA_inf: Pax-beta1 paired domain protein vs. Ensembl Celegans
Match: pax-2 (PAX (Paired box) transcription factor [Source:UniProtKB/TrEMBL;Acc:U4PCL3])

HSP 1 Score: 172.94 bits (437), Expect = 8.302e-48
Identity = 75/130 (57.69%), Postives = 97/130 (74.62%), Query Frame = 3
Query:  633 GAGQNVNQYGRVFTNGRPLPEDLRLKILKMAMENVRPCEISRQLQVSHGCVSKILNRYSRTGSINPGQIGGSKPKVTTPEIVSLVKSYREKNPQIFAWEIRQRLVDEGACTERSAPSISSINRIIRDKGI 1022
            G+   VNQ G VF NGRPLP+ +R +I++M+    RPC+ISRQL+VSHGCVSKIL RY  TGS+ PG IGGSKPKV TP +V  +  Y+  NP +FAWEIRQ+L+++  C E + PS+SSINRI+R+K  
Sbjct:   90 GSHTGVNQLGGVFVNGRPLPDTIRAQIVEMSQHGTRPCDISRQLKVSHGCVSKILGRYYSTGSVRPGVIGGSKPKVATPRVVECIAGYKRANPTMFAWEIRQKLIEDQICGEENVPSVSSINRIVRNKSF 219          
BLAST of TPA_inf: Pax-beta1 paired domain protein vs. Ensembl Celegans
Match: egl-38 (PAX protein [Source:UniProtKB/TrEMBL;Acc:G5ED14])

HSP 1 Score: 168.703 bits (426), Expect = 4.481e-47
Identity = 74/130 (56.92%), Postives = 96/130 (73.85%), Query Frame = 3
Query:  633 GAGQNVNQYGRVFTNGRPLPEDLRLKILKMAMENVRPCEISRQLQVSHGCVSKILNRYSRTGSINPGQIGGSKPKVTTPEIVSLVKSYREKNPQIFAWEIRQRLVDEGACTERSAPSISSINRIIRDKGI 1022
            G+   VNQ G VF NGRPL + +R +I++M+    RPC+ISRQL+VSHGCVSKIL RY  TGS+ PG IGGSKPKV TP +V  +  Y+  NP +FAWEIRQ+L+++  C E + PS+SSINRI+R+K  
Sbjct:   28 GSHTGVNQLGGVFVNGRPLADTVRAQIVEMSQHGTRPCDISRQLKVSHGCVSKILGRYYSTGSVRPGVIGGSKPKVATPRVVECIAGYKRANPTMFAWEIRQKLIEDQICGEENVPSVSSINRIVRNKSF 157          
BLAST of TPA_inf: Pax-beta1 paired domain protein vs. Ensembl Celegans
Match: pax-1 (PAX (Paired box) transcription factor [Source:UniProtKB/TrEMBL;Acc:Q21272])

HSP 1 Score: 159.458 bits (402), Expect = 4.150e-44
Identity = 69/123 (56.10%), Postives = 95/123 (77.24%), Query Frame = 3
Query:  648 VNQYGRVFTNGRPLPEDLRLKILKMAMENVRPCEISRQLQVSHGCVSKILNRYSRTGSINPGQIGGSKPKVTTPEIVSLVKSYREKNPQIFAWEIRQRLVDEGACTERSAPSISSINRIIRDK 1016
            VNQ G VF NGRPLP ++R KI++++ +  RPC+ISRQL++SHGCVSKIL R+S  G+I PG IGGS+P+VTTP++V  ++S +  +P IFAWEIR RL+    C   + PS+SSI+RI+R+K
Sbjct:   65 VNQLGGVFVNGRPLPFEMRCKIVELSRQGTRPCDISRQLKISHGCVSKILTRFSENGTIMPGTIGGSRPRVTTPKVVEYIRSLKRSDPGIFAWEIRDRLISADICDRANLPSVSSISRILRNK 187          
BLAST of TPA_inf: Pax-beta1 paired domain protein vs. Ensembl Celegans
Match: vab-3 (MAB-18 [Source:UniProtKB/TrEMBL;Acc:G5EE71])

HSP 1 Score: 145.976 bits (367), Expect = 2.248e-37
Identity = 67/130 (51.54%), Postives = 90/130 (69.23%), Query Frame = 3
Query:  648 VNQYGRVFTNGRPLPEDLRLKILKMAMENVRPCEISRQLQVSHGCVSKILNRYSRTGSINPGQIGGSKPKVTTPEIVSLVKSYREKNPQIFAWEIRQRLVDEGACTERSAPSISSINRIIRDKGIKTSSV 1037
            VNQ G VF NGRPLP+  R +I+ +A +  RPC+ISR LQVS+GCVSKIL RY  +G+I P  IGGSKP+V T ++V  ++ Y+   P IFAWEIR +L+ +  C   + PS+SSINR++R+   K   V
Sbjct:    9 VNQLGGVFVNGRPLPDATRQRIVDLAHKGCRPCDISRLLQVSNGCVSKILCRYYESGTIRPRAIGGSKPRVATSDVVEKIEDYKRDQPSIFAWEIRDKLLADNICNNETIPSVSSINRVLRNLAAKKEQV 138          
BLAST of TPA_inf: Pax-beta1 paired domain protein vs. Ensembl Fly
Match: Poxm (gene:FBgn0003129 transcript:FBtr0111026)

HSP 1 Score: 167.933 bits (424), Expect = 8.172e-46
Identity = 74/123 (60.16%), Postives = 99/123 (80.49%), Query Frame = 3
Query:  648 VNQYGRVFTNGRPLPEDLRLKILKMAMENVRPCEISRQLQVSHGCVSKILNRYSRTGSINPGQIGGSKPKVTTPEIVSLVKSYREKNPQIFAWEIRQRLVDEGACTERSAPSISSINRIIRDK 1016
            VNQ G VF NGRPLP   R++I+++A   +RPC+ISRQL+VSHGCVSKIL RY  TGSI PG IGGSKP+VTTP++V+ ++  ++++P IFAWEIR RL+ EG C + + PS+SSI+RI+R+K
Sbjct:   13 VNQLGGVFVNGRPLPNATRMRIVELARLGIRPCDISRQLRVSHGCVSKILARYHETGSILPGAIGGSKPRVTTPKVVNYIRELKQRDPGIFAWEIRDRLLSEGICDKTNVPSVSSISRILRNK 135          
BLAST of TPA_inf: Pax-beta1 paired domain protein vs. Ensembl Fly
Match: prd (gene:FBgn0003145 transcript:FBtr0080298)

HSP 1 Score: 172.555 bits (436), Expect = 1.768e-45
Identity = 76/133 (57.14%), Postives = 104/133 (78.20%), Query Frame = 3
Query:  618 QSERAGAGQNVNQYGRVFTNGRPLPEDLRLKILKMAMENVRPCEISRQLQVSHGCVSKILNRYSRTGSINPGQIGGSKPKVTTPEIVSLVKSYREKNPQIFAWEIRQRLVDEGACTERSAPSISSINRIIRDK 1016
            Q   +G G+ VNQ G VF NGRPLP ++RLKI++MA + +RPC ISRQL+VSHGCVSKILNRY  TGSI PG IGGSKP++ TPEI + ++ Y+  +P +F+WEIR++L+ EG C   +APS+S+I+R++R +
Sbjct:   22 QDMNSGQGR-VNQLGGVFINGRPLPNNIRLKIVEMAADGIRPCVISRQLRVSHGCVSKILNRYQETGSIRPGVIGGSKPRIATPEIENRIEEYKRSSPGMFSWEIREKLIREGVCDRSTAPSVSAISRLVRGR 153          
BLAST of TPA_inf: Pax-beta1 paired domain protein vs. Ensembl Fly
Match: prd (gene:FBgn0003145 transcript:FBtr0080299)

HSP 1 Score: 172.17 bits (435), Expect = 1.784e-45
Identity = 73/123 (59.35%), Postives = 99/123 (80.49%), Query Frame = 3
Query:  648 VNQYGRVFTNGRPLPEDLRLKILKMAMENVRPCEISRQLQVSHGCVSKILNRYSRTGSINPGQIGGSKPKVTTPEIVSLVKSYREKNPQIFAWEIRQRLVDEGACTERSAPSISSINRIIRDK 1016
            VNQ G VF NGRPLP ++RLKI++MA + +RPC ISRQL+VSHGCVSKILNRY  TGSI PG IGGSKP++ TPEI + ++ Y+  +P +F+WEIR++L+ EG C   +APS+S+I+R++R +
Sbjct:    8 VNQLGGVFINGRPLPNNIRLKIVEMAADGIRPCVISRQLRVSHGCVSKILNRYQETGSIRPGVIGGSKPRIATPEIENRIEEYKRSSPGMFSWEIREKLIREGVCDRSTAPSVSAISRLVRGR 130          
BLAST of TPA_inf: Pax-beta1 paired domain protein vs. Ensembl Fly
Match: sv (gene:FBgn0005561 transcript:FBtr0301563)

HSP 1 Score: 169.859 bits (429), Expect = 2.007e-45
Identity = 74/126 (58.73%), Postives = 97/126 (76.98%), Query Frame = 3
Query:  648 VNQYGRVFTNGRPLPEDLRLKILKMAMENVRPCEISRQLQVSHGCVSKILNRYSRTGSINPGQIGGSKPKVTTPEIVSLVKSYREKNPQIFAWEIRQRLVDEGACTERSAPSISSINRIIRDKGIK 1025
            VNQ G VF NGRPLP+ +R +I+++A   VRPC+ISRQL+VSHGCVSKIL+RY  TGS   G IGGSKPKV TP +V  + +Y+ +NP +FAWEIR RL+ E  C++ + PS+SSINRI+R+K  +
Sbjct:   23 VNQLGGVFVNGRPLPDVVRQRIVELAHNGVRPCDISRQLRVSHGCVSKILSRYYETGSFKAGVIGGSKPKVATPPVVDAIANYKRENPTMFAWEIRDRLLAEAICSQDNVPSVSSINRIVRNKAAE 148          
BLAST of TPA_inf: Pax-beta1 paired domain protein vs. Ensembl Fly
Match: sv (gene:FBgn0005561 transcript:FBtr0100345)

HSP 1 Score: 171.785 bits (434), Expect = 3.986e-45
Identity = 82/166 (49.40%), Postives = 113/166 (68.07%), Query Frame = 3
Query:  528 EAFGSLSDVKMNCRSKYSSKRSKTGTSCRKQSERAGAGQNVNQYGRVFTNGRPLPEDLRLKILKMAMENVRPCEISRQLQVSHGCVSKILNRYSRTGSINPGQIGGSKPKVTTPEIVSLVKSYREKNPQIFAWEIRQRLVDEGACTERSAPSISSINRIIRDKGIK 1025
            E   +++D++      +SS+ S +G          G G  VNQ G VF NGRPLP+ +R +I+++A   VRPC+ISRQL+VSHGCVSKIL+RY  TGS   G IGGSKPKV TP +V  + +Y+ +NP +FAWEIR RL+ E  C++ + PS+SSINRI+R+K  +
Sbjct:  149 EWITAMNDIQNGAEDSHSSQGSISGD---------GHG-GVNQLGGVFVNGRPLPDVVRQRIVELAHNGVRPCDISRQLRVSHGCVSKILSRYYETGSFKAGVIGGSKPKVATPPVVDAIANYKRENPTMFAWEIRDRLLAEAICSQDNVPSVSSINRIVRNKAAE 304          
BLAST of TPA_inf: Pax-beta1 paired domain protein vs. Ensembl Zebrafish
Match: pax2b (paired box 2b [Source:ZFIN;Acc:ZDB-GENE-001030-4])

HSP 1 Score: 171.785 bits (434), Expect = 1.925e-48
Identity = 78/124 (62.90%), Postives = 96/124 (77.42%), Query Frame = 3
Query:  645 NVNQYGRVFTNGRPLPEDLRLKILKMAMENVRPCEISRQLQVSHGCVSKILNRYSRTGSINPGQIGGSKPKVTTPEIVSLVKSYREKNPQIFAWEIRQRLVDEGACTERSAPSISSINRIIRDK 1016
             VNQ G VF NGRPLP+ +R +I+++A + VRPC+ISRQL+VSHGCVSKIL RY  TGSI PG IGGSKPKV TP++V  +  Y+ +NP +FAWEIR RL+ EG C   + PS+SSINRIIR K
Sbjct:   18 GVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIADYKRQNPTMFAWEIRDRLLAEGICDNDTVPSVSSINRIIRTK 141          
BLAST of TPA_inf: Pax-beta1 paired domain protein vs. Ensembl Zebrafish
Match: pax2a (paired box 2a [Source:NCBI gene;Acc:30425])

HSP 1 Score: 172.94 bits (437), Expect = 2.601e-48
Identity = 78/124 (62.90%), Postives = 96/124 (77.42%), Query Frame = 3
Query:  645 NVNQYGRVFTNGRPLPEDLRLKILKMAMENVRPCEISRQLQVSHGCVSKILNRYSRTGSINPGQIGGSKPKVTTPEIVSLVKSYREKNPQIFAWEIRQRLVDEGACTERSAPSISSINRIIRDK 1016
             VNQ G VF NGRPLP+ +R +I+++A + VRPC+ISRQL+VSHGCVSKIL RY  TGSI PG IGGSKPKV TP++V  +  Y+ +NP +FAWEIR RL+ EG C   + PS+SSINRIIR K
Sbjct:   18 GVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVEKIAEYKRQNPTMFAWEIRDRLLAEGVCDNDTVPSVSSINRIIRTK 141          
BLAST of TPA_inf: Pax-beta1 paired domain protein vs. Ensembl Zebrafish
Match: pax2b (paired box 2b [Source:ZFIN;Acc:ZDB-GENE-001030-4])

HSP 1 Score: 172.94 bits (437), Expect = 1.010e-47
Identity = 78/124 (62.90%), Postives = 96/124 (77.42%), Query Frame = 3
Query:  645 NVNQYGRVFTNGRPLPEDLRLKILKMAMENVRPCEISRQLQVSHGCVSKILNRYSRTGSINPGQIGGSKPKVTTPEIVSLVKSYREKNPQIFAWEIRQRLVDEGACTERSAPSISSINRIIRDK 1016
             VNQ G VF NGRPLP+ +R +I+++A + VRPC+ISRQL+VSHGCVSKIL RY  TGSI PG IGGSKPKV TP++V  +  Y+ +NP +FAWEIR RL+ EG C   + PS+SSINRIIR K
Sbjct:   18 GVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIADYKRQNPTMFAWEIRDRLLAEGICDNDTVPSVSSINRIIRTK 141          
BLAST of TPA_inf: Pax-beta1 paired domain protein vs. Ensembl Zebrafish
Match: pax2a (paired box 2a [Source:NCBI gene;Acc:30425])

HSP 1 Score: 174.096 bits (440), Expect = 1.013e-47
Identity = 78/124 (62.90%), Postives = 96/124 (77.42%), Query Frame = 3
Query:  645 NVNQYGRVFTNGRPLPEDLRLKILKMAMENVRPCEISRQLQVSHGCVSKILNRYSRTGSINPGQIGGSKPKVTTPEIVSLVKSYREKNPQIFAWEIRQRLVDEGACTERSAPSISSINRIIRDK 1016
             VNQ G VF NGRPLP+ +R +I+++A + VRPC+ISRQL+VSHGCVSKIL RY  TGSI PG IGGSKPKV TP++V  +  Y+ +NP +FAWEIR RL+ EG C   + PS+SSINRIIR K
Sbjct:    8 GVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVEKIAEYKRQNPTMFAWEIRDRLLAEGVCDNDTVPSVSSINRIIRTK 131          
BLAST of TPA_inf: Pax-beta1 paired domain protein vs. Ensembl Zebrafish
Match: pax2a (paired box 2a [Source:NCBI gene;Acc:30425])

HSP 1 Score: 173.711 bits (439), Expect = 1.020e-47
Identity = 78/124 (62.90%), Postives = 96/124 (77.42%), Query Frame = 3
Query:  645 NVNQYGRVFTNGRPLPEDLRLKILKMAMENVRPCEISRQLQVSHGCVSKILNRYSRTGSINPGQIGGSKPKVTTPEIVSLVKSYREKNPQIFAWEIRQRLVDEGACTERSAPSISSINRIIRDK 1016
             VNQ G VF NGRPLP+ +R +I+++A + VRPC+ISRQL+VSHGCVSKIL RY  TGSI PG IGGSKPKV TP++V  +  Y+ +NP +FAWEIR RL+ EG C   + PS+SSINRIIR K
Sbjct:    8 GVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVEKIAEYKRQNPTMFAWEIRDRLLAEGVCDNDTVPSVSSINRIIRTK 131          
BLAST of TPA_inf: Pax-beta1 paired domain protein vs. Ensembl Xenopus
Match: aldh1a1 (aldehyde dehydrogenase 1 family member A1 [Source:Xenbase;Acc:XB-GENE-987058])

HSP 1 Score: 173.326 bits (438), Expect = 1.098e-47
Identity = 75/123 (60.98%), Postives = 101/123 (82.11%), Query Frame = 3
Query:  648 VNQYGRVFTNGRPLPEDLRLKILKMAMENVRPCEISRQLQVSHGCVSKILNRYSRTGSINPGQIGGSKPKVTTPEIVSLVKSYREKNPQIFAWEIRQRLVDEGACTERSAPSISSINRIIRDK 1016
            VNQ G VF NGRPLP  +RL+I+++A   +RPC+ISRQL+VSHGCVSKIL RY+ TGSI PG IGGSKP+VTTP +V  +++Y++++P IFAWEIR RL+ +G C + + PS+SSI+RI+R+K
Sbjct:    8 VNQLGGVFVNGRPLPNAIRLRIVELAQLGIRPCDISRQLRVSHGCVSKILARYNETGSILPGAIGGSKPRVTTPTVVKHIRTYKQRDPGIFAWEIRDRLLADGVCDKYNVPSVSSISRILRNK 130          
BLAST of TPA_inf: Pax-beta1 paired domain protein vs. Ensembl Xenopus
Match: aldh1a1 (aldehyde dehydrogenase 1 family member A1 [Source:Xenbase;Acc:XB-GENE-987058])

HSP 1 Score: 173.711 bits (439), Expect = 1.286e-47
Identity = 75/123 (60.98%), Postives = 101/123 (82.11%), Query Frame = 3
Query:  648 VNQYGRVFTNGRPLPEDLRLKILKMAMENVRPCEISRQLQVSHGCVSKILNRYSRTGSINPGQIGGSKPKVTTPEIVSLVKSYREKNPQIFAWEIRQRLVDEGACTERSAPSISSINRIIRDK 1016
            VNQ G VF NGRPLP  +RL+I+++A   +RPC+ISRQL+VSHGCVSKIL RY+ TGSI PG IGGSKP+VTTP +V  +++Y++++P IFAWEIR RL+ +G C + + PS+SSI+RI+R+K
Sbjct:    8 VNQLGGVFVNGRPLPNAIRLRIVELAQLGIRPCDISRQLRVSHGCVSKILARYNETGSILPGAIGGSKPRVTTPTVVKHIRTYKQRDPGIFAWEIRDRLLADGVCDKYNVPSVSSISRILRNK 130          
BLAST of TPA_inf: Pax-beta1 paired domain protein vs. Ensembl Xenopus
Match: igkv7-3 (immunoglobulin kappa variable 7-3 (pseudogene) [Source:Xenbase;Acc:XB-GENE-5762973])

HSP 1 Score: 173.711 bits (439), Expect = 1.380e-47
Identity = 86/162 (53.09%), Postives = 110/162 (67.90%), Query Frame = 3
Query:  645 NVNQYGRVFTNGRPLPEDLRLKILKMAMENVRPCEISRQLQVSHGCVSKILNRYSRTGSINPGQIGGSKPKVTTPEIVSLVKSYREKNPQIFAWEIRQRLVDEGACTERSAPSISSINRIIRDK-------GIKTSSVGRIDEGDIKQLESLSAHSDGSVMS 1109
             VNQ G VF NGRPLP+ +R +I+++A + VRPC+ISRQL+VSHGCVSKIL RY  TGSI PG IGGSKPKV TP++V  +  Y+ +NP +FAWEIR RL+ E  C   + PS+SSINRIIR K        +  S+   +  G + Q+ S+S  S GS  S
Sbjct:   18 GVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVEKIAEYKRQNPTMFAWEIRDRLLAERVCDNDTVPSVSSINRIIRTKVQQPTNQQVPPSNHSIVSTGSVTQVSSVSTDSAGSSYS 179          
BLAST of TPA_inf: Pax-beta1 paired domain protein vs. Ensembl Xenopus
Match: aldh1a1 (aldehyde dehydrogenase 1 family member A1 [Source:Xenbase;Acc:XB-GENE-987058])

HSP 1 Score: 172.94 bits (437), Expect = 1.576e-47
Identity = 75/123 (60.98%), Postives = 101/123 (82.11%), Query Frame = 3
Query:  648 VNQYGRVFTNGRPLPEDLRLKILKMAMENVRPCEISRQLQVSHGCVSKILNRYSRTGSINPGQIGGSKPKVTTPEIVSLVKSYREKNPQIFAWEIRQRLVDEGACTERSAPSISSINRIIRDK 1016
            VNQ G VF NGRPLP  +RL+I+++A   +RPC+ISRQL+VSHGCVSKIL RY+ TGSI PG IGGSKP+VTTP +V  +++Y++++P IFAWEIR RL+ +G C + + PS+SSI+RI+R+K
Sbjct:    8 VNQLGGVFVNGRPLPNAIRLRIVELAQLGIRPCDISRQLRVSHGCVSKILARYNETGSILPGAIGGSKPRVTTPTVVKHIRTYKQRDPGIFAWEIRDRLLADGVCDKYNVPSVSSISRILRNK 130          
BLAST of TPA_inf: Pax-beta1 paired domain protein vs. Ensembl Xenopus
Match: igkv7-3 (immunoglobulin kappa variable 7-3 (pseudogene) [Source:Xenbase;Acc:XB-GENE-5762973])

HSP 1 Score: 173.326 bits (438), Expect = 1.692e-47
Identity = 86/162 (53.09%), Postives = 110/162 (67.90%), Query Frame = 3
Query:  645 NVNQYGRVFTNGRPLPEDLRLKILKMAMENVRPCEISRQLQVSHGCVSKILNRYSRTGSINPGQIGGSKPKVTTPEIVSLVKSYREKNPQIFAWEIRQRLVDEGACTERSAPSISSINRIIRDK-------GIKTSSVGRIDEGDIKQLESLSAHSDGSVMS 1109
             VNQ G VF NGRPLP+ +R +I+++A + VRPC+ISRQL+VSHGCVSKIL RY  TGSI PG IGGSKPKV TP++V  +  Y+ +NP +FAWEIR RL+ E  C   + PS+SSINRIIR K        +  S+   +  G + Q+ S+S  S GS  S
Sbjct:   14 GVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVEKIAEYKRQNPTMFAWEIRDRLLAERVCDNDTVPSVSSINRIIRTKVQQPTNQQVPPSNHSIVSTGSVTQVSSVSTDSAGSSYS 175          
BLAST of TPA_inf: Pax-beta1 paired domain protein vs. Ensembl Mouse
Match: Pax5 (paired box 5 [Source:MGI Symbol;Acc:MGI:97489])

HSP 1 Score: 174.481 bits (441), Expect = 5.019e-50
Identity = 87/161 (54.04%), Postives = 110/161 (68.32%), Query Frame = 3
Query:  648 VNQYGRVFTNGRPLPEDLRLKILKMAMENVRPCEISRQLQVSHGCVSKILNRYSRTGSINPGQIGGSKPKVTTPEIVSLVKSYREKNPQIFAWEIRQRLVDEGACTERSAPSISSINRIIRDK-------GIKTSSVGRIDEGDIKQLESLSAHSDGSVMS 1109
            VNQ G VF NGRPLP+ +R +I+++A + VRPC+ISRQL+VSHGCVSKIL RY  TGSI PG IGGSKPKV TP++V  +  Y+ +NP +FAWEIR RL+ E  C   + PS+SSINRIIR K        +  SS   +  G + Q+ S+S  S GS  S
Sbjct:   19 VNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVEKIAEYKRQNPTMFAWEIRDRLLAERVCDNDTVPSVSSINRIIRTKVQQPPNQPVPASSHSIVSTGSVTQVSSVSTDSAGSSYS 179          
BLAST of TPA_inf: Pax-beta1 paired domain protein vs. Ensembl Mouse
Match: Pax5 (paired box 5 [Source:MGI Symbol;Acc:MGI:97489])

HSP 1 Score: 175.637 bits (444), Expect = 2.394e-49
Identity = 90/168 (53.57%), Postives = 113/168 (67.26%), Query Frame = 3
Query:  627 RAGAGQNVNQYGRVFTNGRPLPEDLRLKILKMAMENVRPCEISRQLQVSHGCVSKILNRYSRTGSINPGQIGGSKPKVTTPEIVSLVKSYREKNPQIFAWEIRQRLVDEGACTERSAPSISSINRIIRDK-------GIKTSSVGRIDEGDIKQLESLSAHSDGSVMS 1109
            R G G  VNQ G VF NGRPLP+ +R +I+++A + VRPC+ISRQL+VSHGCVSKIL RY  TGSI PG IGGSKPKV TP++V  +  Y+ +NP +FAWEIR RL+ E  C   + PS+SSINRIIR K        +  SS   +  G + Q+ S+S  S GS  S
Sbjct:   14 RTGHG-GVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVEKIAEYKRQNPTMFAWEIRDRLLAERVCDNDTVPSVSSINRIIRTKVQQPPNQPVPASSHSIVSTGSVTQVSSVSTDSAGSSYS 180          
BLAST of TPA_inf: Pax-beta1 paired domain protein vs. Ensembl Mouse
Match: Pax5 (paired box 5 [Source:MGI Symbol;Acc:MGI:97489])

HSP 1 Score: 176.792 bits (447), Expect = 2.758e-49
Identity = 90/168 (53.57%), Postives = 113/168 (67.26%), Query Frame = 3
Query:  627 RAGAGQNVNQYGRVFTNGRPLPEDLRLKILKMAMENVRPCEISRQLQVSHGCVSKILNRYSRTGSINPGQIGGSKPKVTTPEIVSLVKSYREKNPQIFAWEIRQRLVDEGACTERSAPSISSINRIIRDK-------GIKTSSVGRIDEGDIKQLESLSAHSDGSVMS 1109
            R G G  VNQ G VF NGRPLP+ +R +I+++A + VRPC+ISRQL+VSHGCVSKIL RY  TGSI PG IGGSKPKV TP++V  +  Y+ +NP +FAWEIR RL+ E  C   + PS+SSINRIIR K        +  SS   +  G + Q+ S+S  S GS  S
Sbjct:   14 RTGHG-GVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVEKIAEYKRQNPTMFAWEIRDRLLAERVCDNDTVPSVSSINRIIRTKVQQPPNQPVPASSHSIVSTGSVTQVSSVSTDSAGSSYS 180          
BLAST of TPA_inf: Pax-beta1 paired domain protein vs. Ensembl Mouse
Match: Pax5 (paired box 5 [Source:MGI Symbol;Acc:MGI:97489])

HSP 1 Score: 176.022 bits (445), Expect = 4.695e-49
Identity = 90/168 (53.57%), Postives = 113/168 (67.26%), Query Frame = 3
Query:  627 RAGAGQNVNQYGRVFTNGRPLPEDLRLKILKMAMENVRPCEISRQLQVSHGCVSKILNRYSRTGSINPGQIGGSKPKVTTPEIVSLVKSYREKNPQIFAWEIRQRLVDEGACTERSAPSISSINRIIRDK-------GIKTSSVGRIDEGDIKQLESLSAHSDGSVMS 1109
            R G G  VNQ G VF NGRPLP+ +R +I+++A + VRPC+ISRQL+VSHGCVSKIL RY  TGSI PG IGGSKPKV TP++V  +  Y+ +NP +FAWEIR RL+ E  C   + PS+SSINRIIR K        +  SS   +  G + Q+ S+S  S GS  S
Sbjct:   14 RTGHG-GVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVEKIAEYKRQNPTMFAWEIRDRLLAERVCDNDTVPSVSSINRIIRTKVQQPPNQPVPASSHSIVSTGSVTQVSSVSTDSAGSSYS 180          
BLAST of TPA_inf: Pax-beta1 paired domain protein vs. Ensembl Mouse
Match: Pax5 (paired box 5 [Source:MGI Symbol;Acc:MGI:97489])

HSP 1 Score: 175.637 bits (444), Expect = 4.734e-49
Identity = 90/168 (53.57%), Postives = 113/168 (67.26%), Query Frame = 3
Query:  627 RAGAGQNVNQYGRVFTNGRPLPEDLRLKILKMAMENVRPCEISRQLQVSHGCVSKILNRYSRTGSINPGQIGGSKPKVTTPEIVSLVKSYREKNPQIFAWEIRQRLVDEGACTERSAPSISSINRIIRDK-------GIKTSSVGRIDEGDIKQLESLSAHSDGSVMS 1109
            R G G  VNQ G VF NGRPLP+ +R +I+++A + VRPC+ISRQL+VSHGCVSKIL RY  TGSI PG IGGSKPKV TP++V  +  Y+ +NP +FAWEIR RL+ E  C   + PS+SSINRIIR K        +  SS   +  G + Q+ S+S  S GS  S
Sbjct:   14 RTGHG-GVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVEKIAEYKRQNPTMFAWEIRDRLLAERVCDNDTVPSVSSINRIIRTKVQQPPNQPVPASSHSIVSTGSVTQVSSVSTDSAGSSYS 180          
BLAST of TPA_inf: Pax-beta1 paired domain protein vs. UniProt/SwissProt
Match: sp|Q02548|PAX5_HUMAN (Paired box protein Pax-5 OS=Homo sapiens OX=9606 GN=PAX5 PE=1 SV=1)

HSP 1 Score: 177.178 bits (448), Expect = 6.908e-48
Identity = 90/171 (52.63%), Postives = 115/171 (67.25%), Query Frame = 3
Query:  618 QSERAGAGQNVNQYGRVFTNGRPLPEDLRLKILKMAMENVRPCEISRQLQVSHGCVSKILNRYSRTGSINPGQIGGSKPKVTTPEIVSLVKSYREKNPQIFAWEIRQRLVDEGACTERSAPSISSINRIIRDK-------GIKTSSVGRIDEGDIKQLESLSAHSDGSVMS 1109
            ++ R G G  VNQ G VF NGRPLP+ +R +I+++A + VRPC+ISRQL+VSHGCVSKIL RY  TGSI PG IGGSKPKV TP++V  +  Y+ +NP +FAWEIR RL+ E  C   + PS+SSINRIIR K        +  SS   +  G + Q+ S+S  S GS  S
Sbjct:   11 RTSRTGHG-GVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVEKIAEYKRQNPTMFAWEIRDRLLAERVCDNDTVPSVSSINRIIRTKVQQPPNQPVPASSHSIVSTGSVTQVSSVSTDSAGSSYS 180          
BLAST of TPA_inf: Pax-beta1 paired domain protein vs. UniProt/SwissProt
Match: sp|Q02650|PAX5_MOUSE (Paired box protein Pax-5 OS=Mus musculus OX=10090 GN=Pax5 PE=1 SV=1)

HSP 1 Score: 176.792 bits (447), Expect = 9.610e-48
Identity = 90/168 (53.57%), Postives = 113/168 (67.26%), Query Frame = 3
Query:  627 RAGAGQNVNQYGRVFTNGRPLPEDLRLKILKMAMENVRPCEISRQLQVSHGCVSKILNRYSRTGSINPGQIGGSKPKVTTPEIVSLVKSYREKNPQIFAWEIRQRLVDEGACTERSAPSISSINRIIRDK-------GIKTSSVGRIDEGDIKQLESLSAHSDGSVMS 1109
            R G G  VNQ G VF NGRPLP+ +R +I+++A + VRPC+ISRQL+VSHGCVSKIL RY  TGSI PG IGGSKPKV TP++V  +  Y+ +NP +FAWEIR RL+ E  C   + PS+SSINRIIR K        +  SS   +  G + Q+ S+S  S GS  S
Sbjct:   14 RTGHG-GVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVEKIAEYKRQNPTMFAWEIRDRLLAERVCDNDTVPSVSSINRIIRTKVQQPPNQPVPASSHSIVSTGSVTQVSSVSTDSAGSSYS 180          
BLAST of TPA_inf: Pax-beta1 paired domain protein vs. UniProt/SwissProt
Match: sp|Q2VL57|PAX9_LEORO (Paired box protein Pax-9 OS=Leontopithecus rosalia OX=30588 GN=PAX9 PE=3 SV=1)

HSP 1 Score: 173.711 bits (439), Expect = 4.115e-47
Identity = 75/123 (60.98%), Postives = 101/123 (82.11%), Query Frame = 3
Query:  648 VNQYGRVFTNGRPLPEDLRLKILKMAMENVRPCEISRQLQVSHGCVSKILNRYSRTGSINPGQIGGSKPKVTTPEIVSLVKSYREKNPQIFAWEIRQRLVDEGACTERSAPSISSINRIIRDK 1016
            VNQ G VF NGRPLP  +RL+I+++A   +RPC+ISRQL+VSHGCVSKIL RY+ TGSI PG IGGSKP+VTTP +V  +++Y++++P IFAWEIR RL+ +G C + + PS+SSI+RI+R+K
Sbjct:    8 VNQLGGVFVNGRPLPNAIRLRIVELAQLGIRPCDISRQLRVSHGCVSKILARYNETGSILPGAIGGSKPRVTTPTVVKHIRTYKQRDPGIFAWEIRDRLLADGVCDKYNVPSVSSISRILRNK 130          
BLAST of TPA_inf: Pax-beta1 paired domain protein vs. UniProt/SwissProt
Match: sp|Q2VL60|PAX9_SAIBB (Paired box protein Pax-9 OS=Saimiri boliviensis boliviensis OX=39432 GN=PAX9 PE=3 SV=1)

HSP 1 Score: 173.326 bits (438), Expect = 4.370e-47
Identity = 75/123 (60.98%), Postives = 101/123 (82.11%), Query Frame = 3
Query:  648 VNQYGRVFTNGRPLPEDLRLKILKMAMENVRPCEISRQLQVSHGCVSKILNRYSRTGSINPGQIGGSKPKVTTPEIVSLVKSYREKNPQIFAWEIRQRLVDEGACTERSAPSISSINRIIRDK 1016
            VNQ G VF NGRPLP  +RL+I+++A   +RPC+ISRQL+VSHGCVSKIL RY+ TGSI PG IGGSKP+VTTP +V  +++Y++++P IFAWEIR RL+ +G C + + PS+SSI+RI+R+K
Sbjct:    8 VNQLGGVFVNGRPLPNAIRLRIVELAQLGIRPCDISRQLRVSHGCVSKILARYNETGSILPGAIGGSKPRVTTPTVVKHIRTYKQRDPGIFAWEIRDRLLADGVCDKYNVPSVSSISRILRNK 130          
BLAST of TPA_inf: Pax-beta1 paired domain protein vs. UniProt/SwissProt
Match: sp|P55166|PAX9_CHICK (Paired box protein Pax-9 (Fragment) OS=Gallus gallus OX=9031 GN=PAX9 PE=2 SV=1)

HSP 1 Score: 173.326 bits (438), Expect = 5.026e-47
Identity = 75/123 (60.98%), Postives = 101/123 (82.11%), Query Frame = 3
Query:  648 VNQYGRVFTNGRPLPEDLRLKILKMAMENVRPCEISRQLQVSHGCVSKILNRYSRTGSINPGQIGGSKPKVTTPEIVSLVKSYREKNPQIFAWEIRQRLVDEGACTERSAPSISSINRIIRDK 1016
            VNQ G VF NGRPLP  +RL+I+++A   +RPC+ISRQL+VSHGCVSKIL RY+ TGSI PG IGGSKP+VTTP +V  +++Y++++P IFAWEIR RL+ +G C + + PS+SSI+RI+R+K
Sbjct:    6 VNQLGGVFVNGRPLPNAIRLRIVELAQLGIRPCDISRQLRVSHGCVSKILARYNETGSILPGAIGGSKPRVTTPTVVKHIRTYKQRDPGIFAWEIRDRLLADGVCDKYNVPSVSSISRILRNK 128          
BLAST of TPA_inf: Pax-beta1 paired domain protein vs. TrEMBL
Match: D5SHI1 (Pax-beta1 paired domain protein (Fragment) OS=Schmidtea mediterranea OX=79327 PE=2 SV=1)

HSP 1 Score: 263.848 bits (673), Expect = 2.638e-81
Identity = 127/128 (99.22%), Postives = 127/128 (99.22%), Query Frame = 3
Query:  636 AGQNVNQYGRVFTNGRPLPEDLRLKILKMAMENVRPCEISRQLQVSHGCVSKILNRYSRTGSINPGQIGGSKPKVTTPEIVSLVKSYREKNPQIFAWEIRQRLVDEGACTERSAPSISSINRIIRDKG 1019
            AGQNVNQYGRVFTNGRPLPEDLRLKILKMAMENVR CEISRQLQVSHGCVSKILNRYSRTGSINPGQIGGSKPKVTTPEIVSLVKSYREKNPQIFAWEIRQRLVDEGACTERSAPSISSINRIIRDKG
Sbjct:    1 AGQNVNQYGRVFTNGRPLPEDLRLKILKMAMENVRRCEISRQLQVSHGCVSKILNRYSRTGSINPGQIGGSKPKVTTPEIVSLVKSYREKNPQIFAWEIRQRLVDEGACTERSAPSISSINRIIRDKG 128          
BLAST of TPA_inf: Pax-beta1 paired domain protein vs. TrEMBL
Match: D5SHI2 (Pax-beta2 paired domain protein (Fragment) OS=Schmidtea mediterranea OX=79327 PE=2 SV=1)

HSP 1 Score: 220.32 bits (560), Expect = 7.321e-65
Identity = 102/127 (80.31%), Postives = 117/127 (92.13%), Query Frame = 3
Query:  639 GQNVNQYGRVFTNGRPLPEDLRLKILKMAMENVRPCEISRQLQVSHGCVSKILNRYSRTGSINPGQIGGSKPKVTTPEIVSLVKSYREKNPQIFAWEIRQRLVDEGACTERSAPSISSINRIIRDKG 1019
            GQN+NQYGR FTNGRPLPE+LRL+ILK+AMENVRPC+ISRQL VSHGCVSKILNRY +TGSINPGQIGGSKPKVTTP+IV  V+ Y+  NPQI+AWEIRQ+L+++  CTE+SAPSISSINRIIRDKG
Sbjct:    2 GQNINQYGRCFTNGRPLPEELRLEILKLAMENVRPCDISRQLCVSHGCVSKILNRYVKTGSINPGQIGGSKPKVTTPDIVDRVRIYKLNNPQIYAWEIRQKLIEDQVCTEQSAPSISSINRIIRDKG 128          
BLAST of TPA_inf: Pax-beta1 paired domain protein vs. TrEMBL
Match: R7TWR1 (Pax-beta paired domain protein (Fragment) OS=Capitella teleta OX=283909 GN=CAPTEDRAFT_115154 PE=4 SV=1)

HSP 1 Score: 215.312 bits (547), Expect = 1.446e-62
Identity = 98/138 (71.01%), Postives = 119/138 (86.23%), Query Frame = 3
Query:  636 AGQNVNQYGRVFTNGRPLPEDLRLKILKMAMENVRPCEISRQLQVSHGCVSKILNRYSRTGSINPGQIGGSKPKVTTPEIVSLVKSYREKNPQIFAWEIRQRLVDEGACTERSAPSISSINRIIRDKGIKTSSVGRID 1049
             G+N+NQYGR+FTNGRPLPE LR++IL++A++ VRPCEISRQLQVSHGCVSKILNRY +TGSINPGQIGGSKPKVTTP++VS V+ Y+ +NPQ+FAWEIRQRL+D+  C E++ PSISSINRIIRDK +     G  D
Sbjct:    3 GGKNINQYGRIFTNGRPLPEHLRVQILQLALQGVRPCEISRQLQVSHGCVSKILNRYRKTGSINPGQIGGSKPKVTTPDVVSRVRQYKIENPQMFAWEIRQRLLDDNICCEKNIPSISSINRIIRDKSLINRRPGSYD 140          
BLAST of TPA_inf: Pax-beta1 paired domain protein vs. TrEMBL
Match: D5SHI0 (Pax-beta paired domain protein (Fragment) OS=Lottia gigantea OX=225164 PE=2 SV=1)

HSP 1 Score: 212.616 bits (540), Expect = 7.025e-62
Identity = 95/128 (74.22%), Postives = 116/128 (90.62%), Query Frame = 3
Query:  636 AGQNVNQYGRVFTNGRPLPEDLRLKILKMAMENVRPCEISRQLQVSHGCVSKILNRYSRTGSINPGQIGGSKPKVTTPEIVSLVKSYREKNPQIFAWEIRQRLVDEGACTERSAPSISSINRIIRDKG 1019
            A +N+NQYGR FTNGRPLPE LR++IL++A++ +RPCEISRQLQVSHGCVSKILNRY +TGSINPGQIGGSKPKVTTP++VS V+ Y+ +NPQ+FAWEIRQ+L+ +G CTE++ PSISSINRIIRDK 
Sbjct:    1 ASRNINQYGRQFTNGRPLPEHLRVQILQLALQGIRPCEISRQLQVSHGCVSKILNRYRKTGSINPGQIGGSKPKVTTPDVVSRVRQYKIENPQMFAWEIRQKLIQDGICTEKNIPSISSINRIIRDKA 128          
BLAST of TPA_inf: Pax-beta1 paired domain protein vs. TrEMBL
Match: D5SHH9 (Pax-beta paired domain protein (Fragment) OS=Capitella teleta OX=283909 PE=2 SV=1)

HSP 1 Score: 211.846 bits (538), Expect = 1.208e-61
Identity = 95/127 (74.80%), Postives = 115/127 (90.55%), Query Frame = 3
Query:  636 AGQNVNQYGRVFTNGRPLPEDLRLKILKMAMENVRPCEISRQLQVSHGCVSKILNRYSRTGSINPGQIGGSKPKVTTPEIVSLVKSYREKNPQIFAWEIRQRLVDEGACTERSAPSISSINRIIRDK 1016
             G+N+NQYGR+FTN RPLPE LR++IL++A++ VRPCEISRQLQVSHGCVSKILNRY +TGSINPGQIGGSKPKVTTP++VS V+ Y+ +NPQ+FAWEIRQRL+D+  C E++ PSISSINRIIRDK
Sbjct:    1 GGKNINQYGRIFTNARPLPEHLRVQILQLALQGVRPCEISRQLQVSHGCVSKILNRYRKTGSINPGQIGGSKPKVTTPDVVSRVRQYKIENPQMFAWEIRQRLLDDNICCEKNIPSISSINRIIRDK 127          
BLAST of TPA_inf: Pax-beta1 paired domain protein vs. Ensembl Cavefish
Match: pax2a (paired box 2 [Source:NCBI gene;Acc:103046873])

HSP 1 Score: 171.785 bits (434), Expect = 2.909e-48
Identity = 78/123 (63.41%), Postives = 96/123 (78.05%), Query Frame = 3
Query:  648 VNQYGRVFTNGRPLPEDLRLKILKMAMENVRPCEISRQLQVSHGCVSKILNRYSRTGSINPGQIGGSKPKVTTPEIVSLVKSYREKNPQIFAWEIRQRLVDEGACTERSAPSISSINRIIRDK 1016
            VNQ G VF NGRPLP+ +R +I+++A + VRPC+ISRQL+VSHGCVSKIL RY  TGSI PG IGGSKPKV TP++V  +  Y+ +NP +FAWEIR RL+ EG C   + PS+SSINRIIR K
Sbjct:   19 VNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGVCDNDTVPSVSSINRIIRTK 141          
BLAST of TPA_inf: Pax-beta1 paired domain protein vs. Ensembl Cavefish
Match: pax8 (paired box 8 [Source:NCBI gene;Acc:103024056])

HSP 1 Score: 174.866 bits (442), Expect = 4.670e-48
Identity = 78/124 (62.90%), Postives = 95/124 (76.61%), Query Frame = 3
Query:  645 NVNQYGRVFTNGRPLPEDLRLKILKMAMENVRPCEISRQLQVSHGCVSKILNRYSRTGSINPGQIGGSKPKVTTPEIVSLVKSYREKNPQIFAWEIRQRLVDEGACTERSAPSISSINRIIRDK 1016
             +NQ G +F NGRPLPE +R +I+ MA + VRPC+ISRQL+VSHGCVSKIL RY  TGSI PG IGGSKPKV TP++V  +  Y+ +NP +FAWEIR RL+ EG C   + PS+SSINRIIR K
Sbjct:   16 GLNQLGGMFVNGRPLPEVIRQRIVDMAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVEKIAEYKRQNPTMFAWEIRDRLLAEGVCDSDTVPSVSSINRIIRTK 139          
BLAST of TPA_inf: Pax-beta1 paired domain protein vs. Ensembl Cavefish
Match: pax2a (paired box 2 [Source:NCBI gene;Acc:103046873])

HSP 1 Score: 173.711 bits (439), Expect = 5.566e-48
Identity = 78/124 (62.90%), Postives = 96/124 (77.42%), Query Frame = 3
Query:  645 NVNQYGRVFTNGRPLPEDLRLKILKMAMENVRPCEISRQLQVSHGCVSKILNRYSRTGSINPGQIGGSKPKVTTPEIVSLVKSYREKNPQIFAWEIRQRLVDEGACTERSAPSISSINRIIRDK 1016
             VNQ G VF NGRPLP+ +R +I+++A + VRPC+ISRQL+VSHGCVSKIL RY  TGSI PG IGGSKPKV TP++V  +  Y+ +NP +FAWEIR RL+ EG C   + PS+SSINRIIR K
Sbjct:   18 GVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGVCDNDTVPSVSSINRIIRTK 141          
BLAST of TPA_inf: Pax-beta1 paired domain protein vs. Ensembl Cavefish
Match: pax9 (paired box 9 [Source:ZFIN;Acc:ZDB-GENE-980526-399])

HSP 1 Score: 170.629 bits (431), Expect = 8.799e-48
Identity = 75/123 (60.98%), Postives = 101/123 (82.11%), Query Frame = 3
Query:  648 VNQYGRVFTNGRPLPEDLRLKILKMAMENVRPCEISRQLQVSHGCVSKILNRYSRTGSINPGQIGGSKPKVTTPEIVSLVKSYREKNPQIFAWEIRQRLVDEGACTERSAPSISSINRIIRDK 1016
            VNQ G VF NGRPLP  +RL+I+++A   +RPC+ISRQL+VSHGCVSKIL RY+ TGSI PG IGGSKP+VTTP +V  +++Y++++P IFAWEIR RL+ +G C + + PS+SSI+RI+R+K
Sbjct:    8 VNQLGGVFVNGRPLPNAIRLRIVELAQLGIRPCDISRQLRVSHGCVSKILARYNETGSILPGAIGGSKPRVTTPTVVKHIRTYKQRDPGIFAWEIRDRLLADGVCDKFNLPSVSSISRILRNK 130          
BLAST of TPA_inf: Pax-beta1 paired domain protein vs. Ensembl Cavefish
Match: pax2a (paired box 2 [Source:NCBI gene;Acc:103046873])

HSP 1 Score: 173.326 bits (438), Expect = 1.169e-47
Identity = 78/123 (63.41%), Postives = 96/123 (78.05%), Query Frame = 3
Query:  648 VNQYGRVFTNGRPLPEDLRLKILKMAMENVRPCEISRQLQVSHGCVSKILNRYSRTGSINPGQIGGSKPKVTTPEIVSLVKSYREKNPQIFAWEIRQRLVDEGACTERSAPSISSINRIIRDK 1016
            VNQ G VF NGRPLP+ +R +I+++A + VRPC+ISRQL+VSHGCVSKIL RY  TGSI PG IGGSKPKV TP++V  +  Y+ +NP +FAWEIR RL+ EG C   + PS+SSINRIIR K
Sbjct:   19 VNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGVCDNDTVPSVSSINRIIRTK 141          
BLAST of TPA_inf: Pax-beta1 paired domain protein vs. Ensembl Sea Lamprey
Match: pax9 (paired box 9 [Source:ZFIN;Acc:ZDB-GENE-980526-399])

HSP 1 Score: 171.785 bits (434), Expect = 1.515e-49
Identity = 75/123 (60.98%), Postives = 102/123 (82.93%), Query Frame = 3
Query:  648 VNQYGRVFTNGRPLPEDLRLKILKMAMENVRPCEISRQLQVSHGCVSKILNRYSRTGSINPGQIGGSKPKVTTPEIVSLVKSYREKNPQIFAWEIRQRLVDEGACTERSAPSISSINRIIRDK 1016
            VNQ G VF NGRPLP  +RL+I++MA   +RPC+ISRQL+VSHGCVSKIL RY+ TGSI PG IGGSKP+VTTP +V+ +++Y++++P IFAWEIR +L+ +G C + + PS+SSI+RI+R+K
Sbjct:    7 VNQLGGVFVNGRPLPNAIRLRIVEMAQLGIRPCDISRQLRVSHGCVSKILARYNETGSILPGAIGGSKPRVTTPNVVNHIRTYKQRDPGIFAWEIRDKLLADGVCDKYNVPSVSSISRILRNK 129          
BLAST of TPA_inf: Pax-beta1 paired domain protein vs. Ensembl Sea Lamprey
Match: pax1a (paired box 1a [Source:ZFIN;Acc:ZDB-GENE-070112-182])

HSP 1 Score: 170.244 bits (430), Expect = 9.890e-48
Identity = 75/123 (60.98%), Postives = 100/123 (81.30%), Query Frame = 3
Query:  648 VNQYGRVFTNGRPLPEDLRLKILKMAMENVRPCEISRQLQVSHGCVSKILNRYSRTGSINPGQIGGSKPKVTTPEIVSLVKSYREKNPQIFAWEIRQRLVDEGACTERSAPSISSINRIIRDK 1016
            VNQ G VF NGRPLP  +RL+I+++A   +RPC+ISRQL+VSHGCVSKIL RY+ TGSI PG IGGSKP+VTTP +V  ++ Y++++P IFAWEIR RL+ +G C + + PS+SSI+RI+R+K
Sbjct:   68 VNQLGGVFVNGRPLPNPIRLRIVELAQLGIRPCDISRQLRVSHGCVSKILARYNETGSILPGAIGGSKPRVTTPNVVKHIRDYKQRDPGIFAWEIRDRLLADGVCDKYNVPSVSSISRILRNK 190          
BLAST of TPA_inf: Pax-beta1 paired domain protein vs. Ensembl Nematostella
Match: PAXC (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SCC8])

HSP 1 Score: 174.866 bits (442), Expect = 1.118e-47
Identity = 84/153 (54.90%), Postives = 110/153 (71.90%), Query Frame = 3
Query:  648 VNQYGRVFTNGRPLPEDLRLKILKMAMENVRPCEISRQLQVSHGCVSKILNRYSRTGSINPGQIGGSKPKVTTPEIVSLVKSYREKNPQIFAWEIRQRLVDEGACTERSAPSISSINRIIRDKGIKTSSVGRIDEGDIKQLESLSA-HSDGSV 1103
            +NQ G  F NGRPLP+ +R +I+++A   VRPCEISR+L VSHGCVSKIL RY  TGSI PG IGGSKPKV TP +V+ +  Y+++NP IFAWEIR RLV+EG C   + PS+SSINRI+R+K  + ++   + E + + L SL   H  G+V
Sbjct:   26 LNQLGGAFVNGRPLPDYIRHRIIQLATYGVRPCEISRRLLVSHGCVSKILGRYYETGSIRPGSIGGSKPKVATPPVVNKILQYKQQNPTIFAWEIRDRLVEEGICDRDNTPSVSSINRILRNKAAERAAQFAMLERERQHLASLYGLHPWGAV 178          
BLAST of TPA_inf: Pax-beta1 paired domain protein vs. Ensembl Nematostella
Match: PAXB (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RN74])

HSP 1 Score: 166.777 bits (421), Expect = 2.192e-44
Identity = 75/123 (60.98%), Postives = 95/123 (77.24%), Query Frame = 3
Query:  648 VNQYGRVFTNGRPLPEDLRLKILKMAMENVRPCEISRQLQVSHGCVSKILNRYSRTGSINPGQIGGSKPKVTTPEIVSLVKSYREKNPQIFAWEIRQRLVDEGACTERSAPSISSINRIIRDK 1016
            VNQ G VF NGRPLP+ +R +I+++A   VRPC+ISRQL+VSHGCVSKIL R+  TGSI PG IGGSKPKV T  +V+ +  Y+  NP +FAWEIR RL+ EG CT  + PS+SSINRI+R++
Sbjct:   11 VNQLGGVFVNGRPLPDVVRQRIVELAQSGVRPCDISRQLRVSHGCVSKILCRFYETGSIKPGVIGGSKPKVATGNVVTKIAEYKLANPTMFAWEIRDRLLSEGVCTSDNVPSVSSINRIVRNR 133          
BLAST of TPA_inf: Pax-beta1 paired domain protein vs. Ensembl Nematostella
Match: PAXA (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S916])

HSP 1 Score: 166.777 bits (421), Expect = 5.806e-44
Identity = 79/144 (54.86%), Postives = 103/144 (71.53%), Query Frame = 3
Query:  648 VNQYGRVFTNGRPLPEDLRLKILKMAMENVRPCEISRQLQVSHGCVSKILNRYSRTGSINPGQIGGSKPKVTTPEIVSLVKSYREKNPQIFAWEIRQRLVDEGACTERSAPSISSINRIIRDKGIKTSSVGRIDEGDIKQLESL 1079
            VNQ G VF NGRPLP+ +R +I+++A   VRP EISRQL VSHGCVSKIL RY  TGS+ PG IGGSKPKV TP++VS +  Y++KNP IFAWEIR  L+ +G C + + PS+SSINRI+R+   +  +  R     +K ++ L
Sbjct:    9 VNQLGGVFVNGRPLPDYMRHRIVELAHCGVRPSEISRQLLVSHGCVSKILGRYYETGSVRPGAIGGSKPKVATPKVVSKILEYKDKNPCIFAWEIRNNLLADGVCDKTNVPSVSSINRILRNSAAEKEA--RAVHEQVKHVQHL 150          
BLAST of TPA_inf: Pax-beta1 paired domain protein vs. Ensembl Nematostella
Match: EDO36623 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SI38])

HSP 1 Score: 139.043 bits (349), Expect = 9.935e-39
Identity = 66/130 (50.77%), Postives = 95/130 (73.08%), Query Frame = 3
Query:  630 AGAGQNVNQYGRVFTNGRPLPEDLRLKILKMAMENVRPCEISRQLQVSHGCVSKILNRYSRTGSINPGQIGGSK-PKVTTPEIVSLVKSYREKNPQIFAWEIRQRLVDEGACTERSAPSISSINRIIRDK 1016
             G G+ VNQ G VF NGRPLP  LR +I+++A   VRPC+ISR+L+VSHGCVSKIL R+ +TGSI PG I GS  P+  TPEI   +  YR +NP +F+WE+R RLV +  C+  + PS+++I+++++++
Sbjct:    1 VGQGR-VNQLGGVFINGRPLPLVLRKQIIELAQLGVRPCDISRRLRVSHGCVSKILYRFQQTGSIEPGAIAGSSTPRNVTPEIEEKIDEYRRENPGMFSWEVRDRLVKDNVCSRCTVPSLAAISQVLKNR 129          
BLAST of TPA_inf: Pax-beta1 paired domain protein vs. Ensembl Nematostella
Match: EDO32510 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SUW0])

HSP 1 Score: 136.346 bits (342), Expect = 9.237e-38
Identity = 57/123 (46.34%), Postives = 89/123 (72.36%), Query Frame = 3
Query:  648 VNQYGRVFTNGRPLPEDLRLKILKMAMENVRPCEISRQLQVSHGCVSKILNRYSRTGSINPGQIGGSKPKVTTPEIVSLVKSYREKNPQIFAWEIRQRLVDEGACTERSAPSISSINRIIRDK 1016
            VNQ G  + NG+PLP ++R++I+++A   VRPCEISR+L+++HGC+SK+L ++ +TGS+ PG +   +P+V T +I   +  YR + P IF+WEIR +L+ EG C     PS+SSI+RI++ K
Sbjct:    1 VNQLGGGYVNGKPLPREIRIQIIELARSGVRPCEISRRLKITHGCISKLLAKFQKTGSLEPGTVYKGRPRVVTSQIEKKIDQYRAEQPGIFSWEIRDQLLQEGICDRSEVPSLSSISRIVKRK 123          
BLAST of TPA_inf: Pax-beta1 paired domain protein vs. Ensembl Medaka
Match: pax8 (paired box 8 [Source:NCBI gene;Acc:101175252])

HSP 1 Score: 177.178 bits (448), Expect = 6.043e-49
Identity = 80/129 (62.02%), Postives = 97/129 (75.19%), Query Frame = 3
Query:  630 AGAGQNVNQYGRVFTNGRPLPEDLRLKILKMAMENVRPCEISRQLQVSHGCVSKILNRYSRTGSINPGQIGGSKPKVTTPEIVSLVKSYREKNPQIFAWEIRQRLVDEGACTERSAPSISSINRIIRDK 1016
            AG    +NQ G +F NGRPLPE +R +I+ MA + VRPC+ISRQL+VSHGCVSKIL RY  TGSI PG IGGSKPKV TP++V  +  Y+ +NP +FAWEIR RL+ EG C   + PS+SSINRIIR K
Sbjct:    5 AGGHGGLNQLGGMFVNGRPLPEVIRQRIVDMAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVEKIAEYKRQNPTMFAWEIRDRLLAEGVCDSDTVPSVSSINRIIRTK 133          
BLAST of TPA_inf: Pax-beta1 paired domain protein vs. Ensembl Medaka
Match: ENSORLT00000038038.1 (paired box 2 [Source:NCBI gene;Acc:100049457])

HSP 1 Score: 172.17 bits (435), Expect = 3.501e-48
Identity = 78/123 (63.41%), Postives = 96/123 (78.05%), Query Frame = 3
Query:  648 VNQYGRVFTNGRPLPEDLRLKILKMAMENVRPCEISRQLQVSHGCVSKILNRYSRTGSINPGQIGGSKPKVTTPEIVSLVKSYREKNPQIFAWEIRQRLVDEGACTERSAPSISSINRIIRDK 1016
            VNQ G VF NGRPLP+ +R +I+++A + VRPC+ISRQL+VSHGCVSKIL RY  TGSI PG IGGSKPKV TP++V  +  Y+ +NP +FAWEIR RL+ EG C   + PS+SSINRIIR K
Sbjct:   19 VNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVEKIADYKRQNPTMFAWEIRDRLLAEGICDNDTVPSVSSINRIIRTK 141          
BLAST of TPA_inf: Pax-beta1 paired domain protein vs. Ensembl Medaka
Match: ENSORLT00000011688.2 (paired box 2 [Source:NCBI gene;Acc:100049457])

HSP 1 Score: 172.94 bits (437), Expect = 8.994e-48
Identity = 78/123 (63.41%), Postives = 96/123 (78.05%), Query Frame = 3
Query:  648 VNQYGRVFTNGRPLPEDLRLKILKMAMENVRPCEISRQLQVSHGCVSKILNRYSRTGSINPGQIGGSKPKVTTPEIVSLVKSYREKNPQIFAWEIRQRLVDEGACTERSAPSISSINRIIRDK 1016
            VNQ G VF NGRPLP+ +R +I+++A + VRPC+ISRQL+VSHGCVSKIL RY  TGSI PG IGGSKPKV TP++V  +  Y+ +NP +FAWEIR RL+ EG C   + PS+SSINRIIR K
Sbjct:   19 VNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVEKIADYKRQNPTMFAWEIRDRLLAEGICDNDTVPSVSSINRIIRTK 141          
BLAST of TPA_inf: Pax-beta1 paired domain protein vs. Ensembl Medaka
Match: pax9 (paired box 9 [Source:NCBI gene;Acc:100335136])

HSP 1 Score: 170.244 bits (430), Expect = 9.402e-48
Identity = 76/127 (59.84%), Postives = 102/127 (80.31%), Query Frame = 3
Query:  636 AGQNVNQYGRVFTNGRPLPEDLRLKILKMAMENVRPCEISRQLQVSHGCVSKILNRYSRTGSINPGQIGGSKPKVTTPEIVSLVKSYREKNPQIFAWEIRQRLVDEGACTERSAPSISSINRIIRDK 1016
            A   VNQ G VF NGRPLP  +RL+I+++A   +RPC+ISRQL+VSHGCVSKIL RY+ TGSI PG IGGSKP+VTTP +V  +++Y++++P IFAWEIR RL+ +G C + + PS+SSI+RI+R+K
Sbjct:    4 AFGEVNQLGGVFVNGRPLPNAIRLRIVELAQLGIRPCDISRQLRVSHGCVSKILARYNETGSILPGAIGGSKPRVTTPTVVKHIRTYKQRDPGIFAWEIRDRLLADGVCDKFNLPSVSSISRILRNK 130          
BLAST of TPA_inf: Pax-beta1 paired domain protein vs. Ensembl Medaka
Match: pax2a (paired box protein Pax-2a [Source:NCBI gene;Acc:101155219])

HSP 1 Score: 173.711 bits (439), Expect = 1.191e-47
Identity = 78/124 (62.90%), Postives = 96/124 (77.42%), Query Frame = 3
Query:  645 NVNQYGRVFTNGRPLPEDLRLKILKMAMENVRPCEISRQLQVSHGCVSKILNRYSRTGSINPGQIGGSKPKVTTPEIVSLVKSYREKNPQIFAWEIRQRLVDEGACTERSAPSISSINRIIRDK 1016
             VNQ G VF NGRPLP+ +R +I+++A + VRPC+ISRQL+VSHGCVSKIL RY  TGSI PG IGGSKPKV TP++V  +  Y+ +NP +FAWEIR RL+ EG C   + PS+SSINRIIR K
Sbjct:   18 GVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGVCDNDTVPSVSSINRIIRTK 141          
BLAST of TPA_inf: Pax-beta1 paired domain protein vs. Planmine SMEST
Match: SMESG000080212.1 (SMESG000080212.1)

HSP 1 Score: 908.672 bits (2347), Expect = 0.000e+0
Identity = 478/480 (99.58%), Postives = 479/480 (99.79%), Query Frame = 3
Query:  258 MDQQIMEKPKQNSLCESSLIKSISINSDHPIIVVAASINSNSKIQEPLNAATNXXXXXXXXXXXXXXXXXXQPNVDGEVLDLSTSSINRDEAFGSLSDVKMNCRSKYSSKRSKTGTSCRKQSERAGAGQNVNQYGRVFTNGRPLPEDLRLKILKMAMENVRPCEISRQLQVSHGCVSKILNRYSRTGSINPGQIGGSKPKVTTPEIVSLVKSYREKNPQIFAWEIRQRLVDEGACTERSAPSISSINRIIRDKGIKTSSVGRIDEGDIKQLESLSAHSDGSVMSNNNSSDRMLNESDSTKQHSEIVDTNLVKQERNSEIVSNDEIPDVECGTLNSSPSIKEELSKMDGIGITGVNQTIMSLWQQQMMTQHPTGSINWGXXXXXXXXXXXXYHSLSCLGQTLWPGQVHTLIETDTSCSDSSEPHNIRPDKVSCRPMVYIGNNQWQLKSSTPFKQSITGSEKASQISQILTQTFPANPVSDS 1697
            MDQQIMEKPKQNSLCESSLIKSISINSDHPIIVVAASINSNSKIQEPLNAATNIAIAPKKDPKKLKEKLIPQPNVDGEVLDLSTSSINRDEAFGSLSDVKMNCRSKYSSKRSKTGTSCRKQSERAGAGQNVNQYGRVFTNGRPLPEDLRLKILKMAMENVRPCEISRQLQVSHGCVSKILNRYSRTGSINPGQIGGSKPKVTTPEIVSLVKSYREKNPQIFAWEIRQRLVDEGACTERSAPSISSINRIIRDKGIKTSSVGRIDEGDIKQLESLSAHSDGSVMSNNNSSDRMLNESDSTKQHSEIVDTNLVKQERNSEIVSNDEIPDVECGTLNSSPSIKEELSKMDG+GITGVNQTIMSLWQQQMMTQHPTGSINWGQAVIAAQLALLQYHSLSCLGQTLWPGQVHTLIETDT CSDSSEPHNIRPDKVSCRPMVYIGNNQWQLKSSTPFKQSITGSEKASQISQILTQTFPANPVSDS
Sbjct:    1 MDQQIMEKPKQNSLCESSLIKSISINSDHPIIVVAASINSNSKIQEPLNAATNIAIAPKKDPKKLKEKLIPQPNVDGEVLDLSTSSINRDEAFGSLSDVKMNCRSKYSSKRSKTGTSCRKQSERAGAGQNVNQYGRVFTNGRPLPEDLRLKILKMAMENVRPCEISRQLQVSHGCVSKILNRYSRTGSINPGQIGGSKPKVTTPEIVSLVKSYREKNPQIFAWEIRQRLVDEGACTERSAPSISSINRIIRDKGIKTSSVGRIDEGDIKQLESLSAHSDGSVMSNNNSSDRMLNESDSTKQHSEIVDTNLVKQERNSEIVSNDEIPDVECGTLNSSPSIKEELSKMDGMGITGVNQTIMSLWQQQMMTQHPTGSINWGQAVIAAQLALLQYHSLSCLGQTLWPGQVHTLIETDTLCSDSSEPHNIRPDKVSCRPMVYIGNNQWQLKSSTPFKQSITGSEKASQISQILTQTFPANPVSDS 480          
BLAST of TPA_inf: Pax-beta1 paired domain protein vs. Planmine SMEST
Match: SMESG000080212.1 (SMESG000080212.1)

HSP 1 Score: 897.116 bits (2317), Expect = 0.000e+0
Identity = 473/475 (99.58%), Postives = 474/475 (99.79%), Query Frame = 3
Query:  273 MEKPKQNSLCESSLIKSISINSDHPIIVVAASINSNSKIQEPLNAATNXXXXXXXXXXXXXXXXXXQPNVDGEVLDLSTSSINRDEAFGSLSDVKMNCRSKYSSKRSKTGTSCRKQSERAGAGQNVNQYGRVFTNGRPLPEDLRLKILKMAMENVRPCEISRQLQVSHGCVSKILNRYSRTGSINPGQIGGSKPKVTTPEIVSLVKSYREKNPQIFAWEIRQRLVDEGACTERSAPSISSINRIIRDKGIKTSSVGRIDEGDIKQLESLSAHSDGSVMSNNNSSDRMLNESDSTKQHSEIVDTNLVKQERNSEIVSNDEIPDVECGTLNSSPSIKEELSKMDGIGITGVNQTIMSLWQQQMMTQHPTGSINWGXXXXXXXXXXXXYHSLSCLGQTLWPGQVHTLIETDTSCSDSSEPHNIRPDKVSCRPMVYIGNNQWQLKSSTPFKQSITGSEKASQISQILTQTFPANPVSDS 1697
            MEKPKQNSLCESSLIKSISINSDHPIIVVAASINSNSKIQEPLNAATNIAIAPKKDPKKLKEKLIPQPNVDGEVLDLSTSSINRDEAFGSLSDVKMNCRSKYSSKRSKTGTSCRKQSERAGAGQNVNQYGRVFTNGRPLPEDLRLKILKMAMENVRPCEISRQLQVSHGCVSKILNRYSRTGSINPGQIGGSKPKVTTPEIVSLVKSYREKNPQIFAWEIRQRLVDEGACTERSAPSISSINRIIRDKGIKTSSVGRIDEGDIKQLESLSAHSDGSVMSNNNSSDRMLNESDSTKQHSEIVDTNLVKQERNSEIVSNDEIPDVECGTLNSSPSIKEELSKMDG+GITGVNQTIMSLWQQQMMTQHPTGSINWGQAVIAAQLALLQYHSLSCLGQTLWPGQVHTLIETDT CSDSSEPHNIRPDKVSCRPMVYIGNNQWQLKSSTPFKQSITGSEKASQISQILTQTFPANPVSDS
Sbjct:    1 MEKPKQNSLCESSLIKSISINSDHPIIVVAASINSNSKIQEPLNAATNIAIAPKKDPKKLKEKLIPQPNVDGEVLDLSTSSINRDEAFGSLSDVKMNCRSKYSSKRSKTGTSCRKQSERAGAGQNVNQYGRVFTNGRPLPEDLRLKILKMAMENVRPCEISRQLQVSHGCVSKILNRYSRTGSINPGQIGGSKPKVTTPEIVSLVKSYREKNPQIFAWEIRQRLVDEGACTERSAPSISSINRIIRDKGIKTSSVGRIDEGDIKQLESLSAHSDGSVMSNNNSSDRMLNESDSTKQHSEIVDTNLVKQERNSEIVSNDEIPDVECGTLNSSPSIKEELSKMDGMGITGVNQTIMSLWQQQMMTQHPTGSINWGQAVIAAQLALLQYHSLSCLGQTLWPGQVHTLIETDTLCSDSSEPHNIRPDKVSCRPMVYIGNNQWQLKSSTPFKQSITGSEKASQISQILTQTFPANPVSDS 475          
BLAST of TPA_inf: Pax-beta1 paired domain protein vs. Planmine SMEST
Match: SMESG000066574.1 (SMESG000066574.1)

HSP 1 Score: 275.789 bits (704), Expect = 3.314e-85
Identity = 168/348 (48.28%), Postives = 220/348 (63.22%), Query Frame = 3
Query:  627 RAGAGQNVNQYGRVFTNGRPLPEDLRLKILKMAMENVRPCEISRQLQVSHGCVSKILNRYSRTGSINPGQIGGSKPKVTTPEIVSLVKSYREKNPQIFAWEIRQRLVDEGACTERSAPSISSINRIIRDKGIKT-------------SSVGRIDEGDIKQLESLSAHSDGSVMSNNNSSDRMLNESDSTKQHSEIVDTNLVKQERNSEIVSNDEIPDVECGTLNSSPS----IKEELSKMDGI-GITGVNQTIMSLWQQQMMTQHPTGSI---NWGXXXXXXXXXXXXYHS--LSCLGQTLWPGQVHTLIETDTSCSDSSEPHNIRPDKVSCRPMVYIGNNQWQLKSS 1601
            +A  GQN+NQYGR FTNGRPLPE+LRL+ILK+AMENVRPC+ISRQL VSHGCVSKILNRY +TGSINPGQIGGSKPKVTTP+IV  V+ Y+  NPQI+AWEIRQ+L+++  CTE+SAPSISSINRIIRDKGI +             S+       +I     LS +SD     NNN  D + +E  S K +S   + +L  +  +SE    + +  +   T NS+P+    I   L  + G   +T ++Q   +      ++   T S    +W  A+I AQ++LLQY S   SC+GQ LWPGQVHTL+  D              +  +C+P++Y+GNNQWQL+SS
Sbjct:   69 KASNGQNINQYGRCFTNGRPLPEELRLEILKLAMENVRPCDISRQLCVSHGCVSKILNRYVKTGSINPGQIGGSKPKVTTPDIVDRVRIYKLNNPQIYAWEIRQKLIEDQVCTEQSAPSISSINRIIRDKGIVSIESASNSDKNPICSAAASETSDNINGKLELSVNSDTLEEVNNNYKDSVADEDGSNKPNSIWPNVSLTPKIISSE----NPVNPINLFT-NSTPTSWNGIPLSLPILPGFPSLTPLSQPPSTAQSSAFISDLATSSSTFQSWATALIHAQMSLLQYQSTMTSCIGQPLWPGQVHTLLSADEQ------------NNSTCQPIIYVGNNQWQLRSS 399          
BLAST of TPA_inf: Pax-beta1 paired domain protein vs. Planmine SMEST
Match: SMESG000004009.1 (SMESG000004009.1)

HSP 1 Score: 169.088 bits (427), Expect = 3.081e-44
Identity = 73/123 (59.35%), Postives = 96/123 (78.05%), Query Frame = 3
Query:  648 VNQYGRVFTNGRPLPEDLRLKILKMAMENVRPCEISRQLQVSHGCVSKILNRYSRTGSINPGQIGGSKPKVTTPEIVSLVKSYREKNPQIFAWEIRQRLVDEGACTERSAPSISSINRIIRDK 1016
            VNQ G +F NGRPLP  +R +I+++A   VRPC+ISRQL+VSHGCVSKIL R+  TGSI PG IGGSKPKV TPE+V  +  Y+ +NP +FAWEIR  L+++  C++ + PS+SSINRI+R+K
Sbjct:   54 VNQLGGLFVNGRPLPNSVRQQIVELAHRGVRPCDISRQLRVSHGCVSKILGRFYETGSIKPGVIGGSKPKVATPEVVEAICKYKAENPTMFAWEIRDMLLNDRVCSQENVPSVSSINRIVRNK 176          
BLAST of TPA_inf: Pax-beta1 paired domain protein vs. Planmine SMEST
Match: SMESG000039056.1 (SMESG000039056.1)

HSP 1 Score: 154.836 bits (390), Expect = 7.930e-40
Identity = 71/133 (53.38%), Postives = 97/133 (72.93%), Query Frame = 3
Query:  612 RKQSERAGAGQNVNQYGRVFTNGRPLPEDLRLKILKMAMENVRPCEISRQLQVSHGCVSKILNRYSRTGSINPGQIGGSKPKVTTPEIVSLVKSYREKNPQIFAWEIRQRLVDEGACTERSAPSISSINRIIR 1010
            +K+ +R  +G  +NQ G +F NGRPLP+  R +I+++A    RPC+ISR LQVS+GCVSKIL RY  TGSI P  IGGSKP+V T  +VS + +Y+ + P IF+WEIR RL+ EG C + + PS+SSINR++R
Sbjct:   12 KKKVKRGHSG--INQLGGMFVNGRPLPDSTRQRIVELAHSGARPCDISRILQVSNGCVSKILCRYYETGSIRPKAIGGSKPRVATSSVVSKIAAYKRECPSIFSWEIRDRLLQEGVCNQDNIPSVSSINRVLR 142          
The following BLAST results are available for this feature:
BLAST of TPA_inf: Pax-beta1 paired domain protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
PAX52.281e-4952.63paired box 5 [Source:HGNC Symbol;Acc:HGNC:8619][more]
PAX52.285e-4952.63paired box 5 [Source:HGNC Symbol;Acc:HGNC:8619][more]
PAX53.000e-4952.63paired box 5 [Source:HGNC Symbol;Acc:HGNC:8619][more]
PAX54.000e-4946.08paired box 5 [Source:HGNC Symbol;Acc:HGNC:8619][more]
PAX54.994e-4952.63paired box 5 [Source:HGNC Symbol;Acc:HGNC:8619][more]
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BLAST of TPA_inf: Pax-beta1 paired domain protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
pax-21.982e-4857.69PAX (Paired box) transcription factor [Source:Uni... [more]
pax-28.302e-4857.69PAX (Paired box) transcription factor [Source:Uni... [more]
egl-384.481e-4756.92PAX protein [Source:UniProtKB/TrEMBL;Acc:G5ED14][more]
pax-14.150e-4456.10PAX (Paired box) transcription factor [Source:Uni... [more]
vab-32.248e-3751.54MAB-18 [Source:UniProtKB/TrEMBL;Acc:G5EE71][more]
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BLAST of TPA_inf: Pax-beta1 paired domain protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Poxm8.172e-4660.16gene:FBgn0003129 transcript:FBtr0111026[more]
prd1.768e-4557.14gene:FBgn0003145 transcript:FBtr0080298[more]
prd1.784e-4559.35gene:FBgn0003145 transcript:FBtr0080299[more]
sv2.007e-4558.73gene:FBgn0005561 transcript:FBtr0301563[more]
sv3.986e-4549.40gene:FBgn0005561 transcript:FBtr0100345[more]
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BLAST of TPA_inf: Pax-beta1 paired domain protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
pax2b1.925e-4862.90paired box 2b [Source:ZFIN;Acc:ZDB-GENE-001030-4][more]
pax2a2.601e-4862.90paired box 2a [Source:NCBI gene;Acc:30425][more]
pax2b1.010e-4762.90paired box 2b [Source:ZFIN;Acc:ZDB-GENE-001030-4][more]
pax2a1.013e-4762.90paired box 2a [Source:NCBI gene;Acc:30425][more]
pax2a1.020e-4762.90paired box 2a [Source:NCBI gene;Acc:30425][more]
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BLAST of TPA_inf: Pax-beta1 paired domain protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
aldh1a11.098e-4760.98aldehyde dehydrogenase 1 family member A1 [Source:... [more]
aldh1a11.286e-4760.98aldehyde dehydrogenase 1 family member A1 [Source:... [more]
igkv7-31.380e-4753.09immunoglobulin kappa variable 7-3 (pseudogene) [So... [more]
aldh1a11.576e-4760.98aldehyde dehydrogenase 1 family member A1 [Source:... [more]
igkv7-31.692e-4753.09immunoglobulin kappa variable 7-3 (pseudogene) [So... [more]
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BLAST of TPA_inf: Pax-beta1 paired domain protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Pax55.019e-5054.04paired box 5 [Source:MGI Symbol;Acc:MGI:97489][more]
Pax52.394e-4953.57paired box 5 [Source:MGI Symbol;Acc:MGI:97489][more]
Pax52.758e-4953.57paired box 5 [Source:MGI Symbol;Acc:MGI:97489][more]
Pax54.695e-4953.57paired box 5 [Source:MGI Symbol;Acc:MGI:97489][more]
Pax54.734e-4953.57paired box 5 [Source:MGI Symbol;Acc:MGI:97489][more]
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BLAST of TPA_inf: Pax-beta1 paired domain protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q02548|PAX5_HUMAN6.908e-4852.63Paired box protein Pax-5 OS=Homo sapiens OX=9606 G... [more]
sp|Q02650|PAX5_MOUSE9.610e-4853.57Paired box protein Pax-5 OS=Mus musculus OX=10090 ... [more]
sp|Q2VL57|PAX9_LEORO4.115e-4760.98Paired box protein Pax-9 OS=Leontopithecus rosalia... [more]
sp|Q2VL60|PAX9_SAIBB4.370e-4760.98Paired box protein Pax-9 OS=Saimiri boliviensis bo... [more]
sp|P55166|PAX9_CHICK5.026e-4760.98Paired box protein Pax-9 (Fragment) OS=Gallus gall... [more]
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BLAST of TPA_inf: Pax-beta1 paired domain protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
D5SHI12.638e-8199.22Pax-beta1 paired domain protein (Fragment) OS=Schm... [more]
D5SHI27.321e-6580.31Pax-beta2 paired domain protein (Fragment) OS=Schm... [more]
R7TWR11.446e-6271.01Pax-beta paired domain protein (Fragment) OS=Capit... [more]
D5SHI07.025e-6274.22Pax-beta paired domain protein (Fragment) OS=Lotti... [more]
D5SHH91.208e-6174.80Pax-beta paired domain protein (Fragment) OS=Capit... [more]
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BLAST of TPA_inf: Pax-beta1 paired domain protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
pax2a2.909e-4863.41paired box 2 [Source:NCBI gene;Acc:103046873][more]
pax84.670e-4862.90paired box 8 [Source:NCBI gene;Acc:103024056][more]
pax2a5.566e-4862.90paired box 2 [Source:NCBI gene;Acc:103046873][more]
pax98.799e-4860.98paired box 9 [Source:ZFIN;Acc:ZDB-GENE-980526-399][more]
pax2a1.169e-4763.41paired box 2 [Source:NCBI gene;Acc:103046873][more]
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BLAST of TPA_inf: Pax-beta1 paired domain protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 2
Match NameE-valueIdentityDescription
pax91.515e-4960.98paired box 9 [Source:ZFIN;Acc:ZDB-GENE-980526-399][more]
pax1a9.890e-4860.98paired box 1a [Source:ZFIN;Acc:ZDB-GENE-070112-182... [more]
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BLAST of TPA_inf: Pax-beta1 paired domain protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of TPA_inf: Pax-beta1 paired domain protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
PAXC1.118e-4754.90Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
PAXB2.192e-4460.98Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
PAXA5.806e-4454.86Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO366239.935e-3950.77Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO325109.237e-3846.34Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of TPA_inf: Pax-beta1 paired domain protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
pax86.043e-4962.02paired box 8 [Source:NCBI gene;Acc:101175252][more]
ENSORLT00000038038.13.501e-4863.41paired box 2 [Source:NCBI gene;Acc:100049457][more]
ENSORLT00000011688.28.994e-4863.41paired box 2 [Source:NCBI gene;Acc:100049457][more]
pax99.402e-4859.84paired box 9 [Source:NCBI gene;Acc:100335136][more]
pax2a1.191e-4762.90paired box protein Pax-2a [Source:NCBI gene;Acc:10... [more]
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BLAST of TPA_inf: Pax-beta1 paired domain protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000080212.10.000e+099.58SMESG000080212.1[more]
SMESG000080212.10.000e+099.58SMESG000080212.1[more]
SMESG000066574.13.314e-8548.28SMESG000066574.1[more]
SMESG000004009.13.081e-4459.35SMESG000004009.1[more]
SMESG000039056.17.930e-4053.38SMESG000039056.1[more]
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Cross References
External references for this transcript
DatabaseAccession
SmedGD GBrowseSMED30018397
GenBankDAA12513.1
Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30018397 ID=SMED30018397|Name=TPA_inf: Pax-beta1 paired domain protein|organism=Schmidtea mediterranea sexual|type=transcript|length=2122bp
GTCGATTCGGTAAATCAGTAACAACCAATCGACTGTGGTTTAGGTATAAA
TCGAACTCACCTGAGTCGTGCTAATTCGTTTACAATTGTATTACTCGATG
AAGGCACACCTCGCTCCGACTCAACCGTAATACATACAGTGAGCTATTAC
CACTCGAATAACAGAGAACTGACACTCTTCTTCTTTTTTCTTATTGAAAA
AAAAAATATCACTCGCACCAGTTGAAATCTCGGAAAGTTGACACGAAAGA
CTCGTAAATGGACCAGCAAATTATGGAAAAACCAAAGCAAAATTCACTCT
GCGAATCTTCATTGATTAAGTCTATATCGATCAATAGCGACCATCCGATT
ATTGTTGTTGCAGCGTCCATTAATTCTAACAGCAAAATCCAGGAACCCTT
AAATGCTGCAACAAATATTGCTATAGCTCCAAAGAAAGATCCAAAAAAAC
TGAAAGAAAAACTCATTCCCCAACCGAATGTCGATGGGGAAGTATTGGAT
TTATCGACTAGTTCTATCAATAGAGATGAGGCATTTGGATCTTTGAGCGA
TGTCAAGATGAATTGTCGATCGAAATATTCATCAAAACGCAGCAAAACTG
GAACATCGTGCAGAAAACAATCTGAAAGAGCAGGTGCCGGTCAAAATGTC
AATCAATACGGTCGAGTATTCACAAATGGTAGACCATTGCCAGAAGATTT
GAGGTTAAAAATTTTGAAAATGGCAATGGAAAATGTCAGACCTTGTGAAA
TCTCAAGACAATTACAAGTATCCCATGGATGCGTTAGCAAAATTTTGAAT
AGATATTCACGAACCGGATCTATCAATCCTGGTCAAATTGGGGGTTCGAA
ACCTAAAGTTACAACTCCGGAAATTGTGTCCCTCGTTAAATCATATCGAG
AAAAGAATCCTCAGATTTTCGCATGGGAAATTAGACAAAGGCTAGTGGAT
GAAGGAGCTTGCACAGAAAGATCGGCACCGAGTATATCGTCCATCAATAG
AATTATACGGGATAAAGGAATTAAGACTTCTTCAGTCGGTCGTATAGATG
AAGGAGATATAAAGCAACTTGAATCTTTGAGTGCGCATTCTGATGGATCC
GTTATGTCTAACAACAATAGTAGTGATCGGATGTTGAATGAATCTGATTC
AACCAAACAACATTCAGAGATTGTAGATACAAATTTAGTCAAGCAAGAAA
GAAATTCAGAGATCGTTAGCAACGACGAAATTCCGGACGTTGAATGCGGA
ACACTAAATTCATCTCCCTCTATAAAAGAAGAACTATCCAAAATGGATGG
CATAGGAATAACTGGAGTAAATCAAACTATAATGTCACTTTGGCAGCAGC
AAATGATGACCCAACATCCGACAGGATCAATAAATTGGGGACAAGCTGTT
ATAGCTGCACAACTAGCACTTCTTCAGTACCATTCATTATCTTGTCTCGG
GCAAACTTTGTGGCCTGGACAAGTTCATACTCTCATAGAAACTGATACTT
CATGTTCAGATTCATCAGAACCACATAATATTAGACCGGATAAAGTCTCA
TGTCGTCCTATGGTTTACATTGGAAATAATCAGTGGCAATTAAAATCATC
AACTCCGTTCAAACAAAGTATCACCGGAAGTGAAAAGGCTTCTCAAATCT
CTCAAATCTTAACACAAACATTTCCTGCAAATCCTGTTTCAGATTCTTGA
GTTCTACACATATCTCTAATATCTGTGTATATTGTAAAAACGTTTTATTA
ATTCGATAAATATTTAATGGTATTTCGTAAAAAGTGAAAAGAAAGTATAA
TTAATGTATTTAAAGTGCCAATAAATGTCTATTAGAAATCAATTACAGAA
AATTACCAGGCATATCATTCGATAAGTTTGTTATGCATACTCCTAATTCC
ATTGCAAAATTTGACAGGTTGATATCAGTAAAATTTTGCTGGAGTCGATT
TTGATTGGTTGGAATTTCTATCATGATTTCGCATGATTCTACAATTCATT
TTTCTTTTAATTATTGTTGGTTTGTTTTCATTTTTCAATTCCTACTACTG
TGAATTAATCAATAAGTAGCTAAAACCATATTTAGTATTAGCTAAAATAA
AGGAGTTATTTTAAAAACGTGC
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protein sequence of SMED30018397-orf-1

>SMED30018397-orf-1 ID=SMED30018397-orf-1|Name=SMED30018397-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=481bp
MDQQIMEKPKQNSLCESSLIKSISINSDHPIIVVAASINSNSKIQEPLNA
ATNIAIAPKKDPKKLKEKLIPQPNVDGEVLDLSTSSINRDEAFGSLSDVK
MNCRSKYSSKRSKTGTSCRKQSERAGAGQNVNQYGRVFTNGRPLPEDLRL
KILKMAMENVRPCEISRQLQVSHGCVSKILNRYSRTGSINPGQIGGSKPK
VTTPEIVSLVKSYREKNPQIFAWEIRQRLVDEGACTERSAPSISSINRII
RDKGIKTSSVGRIDEGDIKQLESLSAHSDGSVMSNNNSSDRMLNESDSTK
QHSEIVDTNLVKQERNSEIVSNDEIPDVECGTLNSSPSIKEELSKMDGIG
ITGVNQTIMSLWQQQMMTQHPTGSINWGQAVIAAQLALLQYHSLSCLGQT
LWPGQVHTLIETDTSCSDSSEPHNIRPDKVSCRPMVYIGNNQWQLKSSTP
FKQSITGSEKASQISQILTQTFPANPVSDS*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000016pharynx
PLANA:0000099neuron
PLANA:0000420parapharyngeal region
Vocabulary: INTERPRO
TermDefinition
IPR036388WH-like_DNA-bd_sf
IPR043182PAIRED_DNA_bd_dom
IPR001523Paired_dom
IPR011991WHTH_DNA-bd_dom
IPR009057Homeobox-like_sf
Vocabulary: biological process
TermDefinition
GO:0006355regulation of transcription, DNA-templated
GO:0006351transcription, DNA-templated
GO:0007275multicellular organism development
Vocabulary: molecular function
TermDefinition
GO:0003677DNA binding
Vocabulary: cellular component
TermDefinition
GO:0005634nucleus
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR001523Paired domainPRINTSPR00027PAIREDBOXcoord: 149..167
score: 52.99
coord: 169..186
score: 76.53
coord: 131..146
score: 73.1
coord: 187..204
score: 74.59
IPR001523Paired domainSMARTSM00351pax3coord: 127..251
e-value: 2.5E-72
score: 256.3
IPR001523Paired domainPFAMPF00292PAXcoord: 130..251
e-value: 5.5E-56
score: 187.9
IPR001523Paired domainPROSITEPS51057PAIRED_2coord: 127..253
score: 53.289
IPR036388Winged helix-like DNA-binding domain superfamilyGENE3DG3DSA:1.10.10.10coord: 127..195
e-value: 9.9E-33
score: 113.8
IPR036388Winged helix-like DNA-binding domain superfamilyGENE3DG3DSA:1.10.10.10coord: 196..259
e-value: 9.9E-27
score: 94.4
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 275..294
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 108..129
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 106..129
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 275..302
NoneNo IPR availablePANTHERPTHR45636:SF7PAIRED BOX POX-NEURO PROTEIN-RELATEDcoord: 102..376
NoneNo IPR availablePANTHERPTHR45636FAMILY NOT NAMEDcoord: 102..376
IPR043182Paired DNA-binding domainPROSITEPS00034PAIRED_1coord: 161..177
IPR009057Homeobox-like domain superfamilySUPERFAMILYSSF46689Homeodomain-likecoord: 130..254