Polypeptide N-acetylgalactosaminyltransferase

Query:  265 KRMNSTRRFN--NSFEEEKVSLYRTINELKITKCKWLRHNKTLPSVSIIITFYDSDWEXXXXXXXXXXXXSPRRLIKEXXXXXXXXXXXXMRSKMNAYISKNFTNVRVVHKTKREXXXXXXXXXXXXXXXXVLVFMDSHCTVGVKWLPPLLEPIKENYKTVTCPFIDINDTDTSLYSQDEG--ARGAFDWNFNYTRLP-RLHNNKTDPEDPFDNPIMQGRIFAITRKWFWELGGYDEGLEIWGGEQFELSFKIWMCGGRMVNVPCSRIRCIFKDIYSFDFIHDDIKIRKNYKRIAEIWMDNWKKFIYQRHLEEYSSFDCGDISXXXXXXXXXNCKSFDWFMENVAYDILYLYPPITVSEKLNCSITLESDDSICVDSKYRKQGDRVGIDQCNQIGRSEK--NKEQRFSFTSDFEIRPGQ----RNLCFDYRNSSETLMLSQCDLMNPNQKWEY 1590
            +R++   R N  N +  +K+SL R++ +++   C   R+ +TLP+ SIII F++  W +L++T   +L RSP  L+ EI+++DD +D   ++  +  Y++  F +VR++   KREGLI+ R+LGA +A G V+ F+DSHC   V WLPPLL+ I  N KT+ CP ID+ D D   Y    G   RGAFDW   Y R+P      K DP DPF++P+M G +FA+ RKWFWELGGYD GLEIWGGEQ+E+SFK+WMCGGRM ++PCSR+  I++    +  +   + + +N KR+AE+WMD + ++IYQR   EY     GD++ QKKL+  LNCKSF WFM  +A+D+   YPP+         I       +C D+K+   G  + ++ C + GR E   N  Q F+FT   +IRPG     +  CFD  + +  + L  C  M  NQ W+Y
Sbjct:  102 ERVDQAYRENGFNIYVSDKISLNRSLPDIRHPNCNSKRYLETLPNTSIIIPFHNEGWSSLLRTVHSVLNRSPPELVAEIVLVDDFSDREHLKKPLEDYMAL-FPSVRILRTKKREGLIRTRMLGASVATGDVITFLDSHCEANVNWLPPLLDRIARNRKTIVCPMIDVIDHDDFRYETQAGDAMRGAFDWEMYYKRIPIPPELQKADPSDPFESPVMAGGLFAVDRKWFWELGGYDPGLEIWGGEQYEISFKVWMCGGRMEDIPCSRVGHIYRKYVPYK-VPAGVSLARNLKRVAEVWMDEYAEYIYQRR-PEYRHLSAGDVAVQKKLRSSLNCKSFKWFMTKIAWDLPKFYPPVEPPAAAWGEIR-NVGTGLCADTKHGALGSPLRLEGCVR-GRGEAAWNNMQVFTFTWREDIRPGDPQHTKKFCFDAISHTSPVTLYDCHSMKGNQLWKY 549          

Query:  295 NSFEEEKVSLYRTINELKITKCKWLRHNKTLPSVSIIITFYDSDWEXXXXXXXXXXXXSPRRLIKEXXXXXXXXXXXXMRSKMNAYISKNFTNVRVVHKTKREXXXXXXXXXXXXXXXXVLVFMDSHCTVGVKWLPPLLEPIKENYKTVTCPFIDINDTDTSLYSQDEG--ARGAFDWNFNYTRLP-RLHNNKTDPEDPFDNPIMQGRIFAITRKWFWELGGYDEGLEIWGGEQFELSFKIWMCGGRMVNVPCSRIRCIFKDIYSFDFIHDDIKIRKNYKRIAEIWMDNWKKFIYQRHLEEYSSFDCGDISXXXXXXXXXNCKSFDWFMENVAYDILYLYPPITVSEKLNCSITLESDDSICVDSKYRKQGDRVGIDQCNQIGRSEK--NKEQRFSFTSDFEIRPGQ----RNLCFDYRNSSETLMLSQCDLMNPNQKWEY---NSTSHQITN 1617
            N F    ++L R++ +++   CK   + + LP+ SIII F++  W +L++T   ++ R+P  LI EI+++DD ++   ++ K+  Y+++ F+ VR+V   KREGLI+ RLLGA +A+G+VL F+DSHC V V WLPPLL  I  N+KT+ CP ID+ D +   Y    G   RGAFDW   Y R+P      + DP DPF++P+M G +FA+ RKWFWELGGYD GLEIWGGEQ+E+SFK+WMCGG M +VPCSR+  I++    +  +     + +N KR+AE WMD + ++IYQR   EY     GDIS QK+L+++L CK F WFM  VA+D+   YPP+         I      ++CVDSK+   G  + +D C + G SE+  + EQ F+F    +IRPG+    R  CFD  + +  + L  C  M  NQ W Y    +  H ++N
Sbjct:   92 NIFVSNNIALERSLPDIRHANCKHKMYLERLPNTSIIIPFHNEGWTSLLRTIHSIINRTPGSLIAEIILVDDFSEREHLKDKLEEYMAR-FSKVRIVRTKKREGLIRTRLLGASMARGEVLTFLDSHCEVNVNWLPPLLNQIALNHKTIVCPMIDVIDHNHFGYEAQAGDAMRGAFDWEMYYKRIPIPPELQRADPSDPFESPVMAGGLFAVDRKWFWELGGYDPGLEIWGGEQYEISFKVWMCGGEMFDVPCSRVGHIYRKYVPYK-VPSGTSLARNLKRVAETWMDEFAEYIYQRR-PEYRHLSTGDISAQKELRKQLKCKDFKWFMAAVAWDVPKYYPPVEPPPAAWGEIR-NVAANLCVDSKHGATGTELRLDICVKDG-SERTWSHEQLFTFGWREDIRPGEPLHTRKFCFDAISHNSPVTLYDCHGMKGNQLWGYRKDRTLFHPVSN 539          

Query:  295 NSFEEEKVSLYRTINELKITKCKWLRHNKTLPSVSIIITFYDSDWEXXXXXXXXXXXXSPRRLIKEXXXXXXXXXXXXMRSKMNAYISKNFTNVRVVHKTKREXXXXXXXXXXXXXXXXVLVFMDSHCTVGVKWLPPLLEPIKENYKTVTCPFIDINDTDTSLYSQDEG--ARGAFDWNFNYTRLP-RLHNNKTDPEDPFDNPIMQGRIFAITRKWFWELGGYDEGLEIWGGEQFELSFKIWMCGGRMVNVPCSRIRCIFKDIYSFDFIHDDIKIRKNYKRIAEIWMDNWKKFIYQRHLEEYSSFDCGDISXXXXXXXXXNCKSFDWFMENVAYDILYLYPPITVSEKLNCSITLESDDSICVDSKYRKQGDRVGIDQCNQIGRSEK--NKEQRFSFTSDFEIRPGQ----RNLCFDYRNSSETLMLSQCDLMNPNQKWEY---NSTSHQITN 1617
            N F    ++L R++ +++   CK   + + LP+ SIII F++  W +L++T   ++ R+P  LI EI+++DD ++   ++ K+  Y+++ F+ VR+V   KREGLI+ RLLGA +A+G+VL F+DSHC V V WLPPLL  I  N+KT+ CP ID+ D +   Y    G   RGAFDW   Y R+P      + DP DPF++P+M G +FA+ RKWFWELGGYD GLEIWGGEQ+E+SFK+WMCGG M +VPCSR+  I++    +  +     + +N KR+AE WMD + ++IYQR   EY     GDIS QK+L+++L CK F WFM  VA+D+   YPP+         I      ++CVDSK+   G  + +D C + G SE+  + EQ F+F    +IRPG+    R  CFD  + +  + L  C  M  NQ W Y    +  H ++N
Sbjct:  109 NIFVSNNIALERSLPDIRHANCKHKMYLERLPNTSIIIPFHNEGWTSLLRTIHSIINRTPGSLIAEIILVDDFSEREHLKDKLEEYMAR-FSKVRIVRTKKREGLIRTRLLGASMARGEVLTFLDSHCEVNVNWLPPLLNQIALNHKTIVCPMIDVIDHNHFGYEAQAGDAMRGAFDWEMYYKRIPIPPELQRADPSDPFESPVMAGGLFAVDRKWFWELGGYDPGLEIWGGEQYEISFKVWMCGGEMFDVPCSRVGHIYRKYVPYK-VPSGTSLARNLKRVAETWMDEFAEYIYQRR-PEYRHLSTGDISAQKELRKQLKCKDFKWFMAAVAWDVPKYYPPVEPPPAAWGEIR-NVAANLCVDSKHGATGTELRLDICVKDG-SERTWSHEQLFTFGWREDIRPGEPLHTRKFCFDAISHNSPVTLYDCHGMKGNQLWGYRKDRTLFHPVSN 556          

Query:  529 MRSKMNAYISKNFTNVRVVHKTKREXXXXXXXXXXXXXXXXVLVFMDSHCTVGVKWLPPLLEPIKENYKTVTCPFIDINDTDTSLYSQDEG--ARGAFDWNFNYTRLP-RLHNNKTDPEDPFDNPIMQGRIFAITRKWFWELGGYDEGLEIWGGEQFELSFKIWMCGGRMVNVPCSRIRCIFKDIYSFDFIHDDIKIRKNYKRIAEIWMDNWKKFIYQRHLEEYSSFDCGDISXXXXXXXXXNCKSFDWFMENVAYDILYLYPPITVSEKLNCSITLESDDSICVDSKYRKQGDRVGIDQCNQIGRSEK--NKEQRFSFTSDFEIRPGQ----RNLCFDYRNSSETLMLSQCDLMNPNQKWEY---NSTSHQITN 1617
            ++ K+  Y+++ F+ VR+V   KREGLI+ RLLGA +A+G+VL F+DSHC V V WLPPLL  I  N+KT+ CP ID+ D +   Y    G   RGAFDW   Y R+P      + DP DPF++P+M G +FA+ RKWFWELGGYD GLEIWGGEQ+E+SFK+WMCGG M +VPCSR+  I++    +  +     + +N KR+AE WMD + ++IYQR   EY     GDIS QK+L+++L CK F WFM  VA+D+   YPP+         I      ++CVDSK+   G  + +D C + G SE+  + EQ F+F    +IRPG+    R  CFD  + +  + L  C  M  NQ W Y    +  H ++N
Sbjct:    3 LKDKLEEYMAR-FSKVRIVRTKKREGLIRTRLLGASMARGEVLTFLDSHCEVNVNWLPPLLNQIALNHKTIVCPMIDVIDHNHFGYEAQAGDAMRGAFDWEMYYKRIPIPPELQRADPSDPFESPVMAGGLFAVDRKWFWELGGYDPGLEIWGGEQYEISFKVWMCGGEMFDVPCSRVGHIYRKYVPYK-VPSGTSLARNLKRVAETWMDEFAEYIYQRR-PEYRHLSTGDISAQKELRKQLKCKDFKWFMAAVAWDVPKYYPPVEPPPAAWGEIR-NVAANLCVDSKHGATGTELRLDICVKDG-SERTWSHEQLFTFGWREDIRPGEPLHTRKFCFDAISHNSPVTLYDCHGMKGNQLWGYRKDRTLFHPVSN 372          

Query:  718 IKENYKTVTCPFIDINDTDTSLYSQDEG--ARGAFDWNFNYTRLPRLHN-NKTDPEDPFDNPIMQGRIFAITRKWFWELGGYDEGLEIWGGEQFELSFKIWMCGGRMVNVPCSRIRCIFKDIYSFDFIHDDIKIRKNYKRIAEIWMDNWKKFIYQRHLEEYSSFDCGDISXXXXXXXXXNCKSFDWFMENVAYDILYLYPPITVSEKLNCSITLESDDSICVDSKYRKQGDRVGIDQCNQIGRSEK--NKEQRFSFTSDFEIRPGQ----RNLCFDYRNSSETLMLSQCDLMNPNQKWEY 1590
            I  N KT+ CP ID+ D D   Y    G   RGAFDW   Y R+P      K DP DPF++P+M G +FA+ RKWFWELGGYD GLEIWGGEQ+E+SFK+WMCGGRM ++PCSR+  I++    +  +   + + +N KR+AE+WMD + ++IYQR   EY     GD++ QKKL+  LNCKSF WFM  +A+D+   YPP+         I       +C D+K+   G  + ++ C + GR E   N  Q F+FT   +IRPG     +  CFD  + +  + L  C  M  NQ W+Y
Sbjct:  192 IARNRKTIVCPMIDVIDHDDFRYETQAGDAMRGAFDWEMYYKRIPIPPELQKADPSDPFESPVMAGGLFAVDRKWFWELGGYDPGLEIWGGEQYEISFKVWMCGGRMEDIPCSRVGHIYRKYVPYK-VPAGVSLARNLKRVAEVWMDEYAEYIYQRR-PEYRHLSAGDVAVQKKLRSSLNCKSFKWFMTKIAWDLPKFYPPVEPPAAAWGEIR-NVGTGLCADTKHGALGSPLRLEGCVR-GRGEAAWNNMQVFTFTWREDIRPGDPQHTKKFCFDAISHTSPVTLYDCHSMKGNQLWKY 487          

Query:  295 NSFEEEKVSLYRTINELKITKCKWLRHNKTLPSVSIIITFYDSDWEXXXXXXXXXXXXSPRRLIKEXXXXXXXXXXXXMRSKMNAYISKNFTN--VRVVHKTKREXXXXXXXXXXXXXXXXVLVFMDSHCTVGVKWLPPLLEPIKENYKTVTCPFIDINDTDT-SLYSQDEGARGAFDWNFNYTRLPRLHNNKTDPEDPFDNPIMQGRIFAITRKWFWELGGYDEGLEIWGGEQFELSFKIWMCGGRMVNVPCSRIRCIFKDIYS-FDFIHDDIKIRKNYKRIAEIWMDNWKKFIYQRHLEEYSSFDCGDISXXXXXXXXXNCKSFDWFMENVAYDILYLYPPITVSEKLNCSITLESDDSICVDSKYRKQGDRVGIDQCNQIGRSEKNKEQRFSFTSDFEIRPGQRNLCFDYRNSSE--TLMLSQCDLMNPNQKWEYNSTSHQITNIPSQKCI 1638
            N++  + +SL R+I +++  +CK + ++  LP+VS+I  F++    TL+++   ++ RSP  L+KEI+++DD ++   +R  +  ++ KN  +  V+V+   KREGLI+ R LGA+ A G++L+F+D+H      WLPPLL+PI E+Y+TV CPF+D+ D +T  +  QDEGARG+FDW FNY RLP    ++  P  PF++P+M G  FAI+ KWFWELGGYDEGL+IWGGEQ+ELSFK+W C GRMV+ PCSR+  I++  Y+ F        + +NYKR+AE+WMD++K+ +Y +H     + D GD+   K +++KL CKSFDWFM+ +A+D    YP +         I      + C+D+++++Q  R G+ +C    + +   EQ    T   +IRP  R +CFD   S +   ++L  C  M  NQ ++Y     QI +  S +C+
Sbjct:  126 NAYISDMISLNRSIKDIRHKECKNMMYSAKLPTVSVIFPFHEEHNSTLLRSVYSVINRSPPELLKEIILVDDFSEKPALRQPLEDFLKKNKIDHIVKVLRTKKREGLIRGRQLGAQDATGEILIFLDAHSEANYNWLPPLLDPIAEDYRTVVCPFVDVIDCETYEVRPQDEGARGSFDWAFNYKRLPLTKKDRESPTKPFNSPVMAGGYFAISAKWFWELGGYDEGLDIWGGEQYELSFKVWQCHGRMVDAPCSRVAHIYRCKYAPFKNAGMGDFVSRNYKRVAEVWMDDYKETLY-KHRPGVGNADAGDLKLMKGIREKLQCKSFDWFMKEIAFDQDKYYPAVEPKASAEGEIR-NVGTNFCIDTQFKEQNQRFGLRKCTSDDK-DGGGEQDLRLTRWHDIRPKGRKICFDCSTSVDKAPVILFDCHSMKGNQLFKYRVAQKQIYHPISGQCL 576          

Query:  295 NSFEEEKVSLYRTINELKITKCKWLRHNKTLPSVSIIITFYDSDWEXXXXXXXXXXXXSPRRLIKEXXXXXXXXXXXXMRSKMNAYISKNFTN--VRVVHKTKREXXXXXXXXXXXXXXXXVLVFMDSHCTVGVKWLPPLLEPIKENYKTVTCPFIDINDTDT-SLYSQDEGARGAFDWNFNYTRLPRLHNNKTDPEDPFDNPIMQGRIFAITRKWFWELGGYDEGLEIWGGEQFELSFKIWMCGGRMVNVPCSRIRCIFKDIYS-FDFIHDDIKIRKNYKRIAEIWMDNWKKFIYQRHLEEYSSFDCGDISXXXXXXXXXNCKSFDWFMENVAYDILYLYPPITVSEKLNCSITLESDDSICVDSKYRKQGDRVGIDQCNQIGRSEKNKEQRFSFTSDFEIRPGQRNLCFDYRNSSE--TLMLSQCDLMNPNQKWEYNSTSHQITNIPSQKCI 1638
            N++  + +SL R+I +++  +CK + ++  LP+VS+I  F++    TL+++   ++ RSP  L+KEI+++DD ++   +R  +  ++ KN  +  V+V+   KREGLI+ R LGA+ A G++L+F+D+H      WLPPLL+PI E+Y+TV CPF+D+ D +T  +  QDEGARG+FDW FNY RLP    ++  P  PF++P+M G  FAI+ KWFWELGGYDEGL+IWGGEQ+ELSFK+W C GRMV+ PCSR+  I++  Y+ F        + +NYKR+AE+WMD++K+ +Y +H     + D GD+   K +++KL CKSFDWFM+ +A+D    YP +         I      + C+D+++++Q  R G+ +C    + +   EQ    T   +IRP  R +CFD   S +   ++L  C  M  NQ ++Y     QI +  S +C+
Sbjct:  207 NAYISDMISLNRSIKDIRHKECKNMMYSAKLPTVSVIFPFHEEHNSTLLRSVYSVINRSPPELLKEIILVDDFSEKPALRQPLEDFLKKNKIDHIVKVLRTKKREGLIRGRQLGAQDATGEILIFLDAHSEANYNWLPPLLDPIAEDYRTVVCPFVDVIDCETYEVRPQDEGARGSFDWAFNYKRLPLTKKDRESPTKPFNSPVMAGGYFAISAKWFWELGGYDEGLDIWGGEQYELSFKVWQCHGRMVDAPCSRVAHIYRCKYAPFKNAGMGDFVSRNYKRVAEVWMDDYKETLY-KHRPGVGNADAGDLKLMKGIREKLQCKSFDWFMKEIAFDQDKYYPAVEPKASAEGEIR-NVGTNFCIDTQFKEQNQRFGLRKCTSDDK-DGGGEQDLRLTRWHDIRPKGRKICFDCSTSVDKAPVILFDCHSMKGNQLFKYRVAQKQIYHPISGQCL 657          

Query:  295 NSFEEEKVSLYRTINELKITKCKWLRHNKTLPSVSIIITFYDSDWEXXXXXXXXXXXXSPRRLIKEXXXXXXXXXXXXMRSKMNAYISKNFTNVRVVHKTKREXXXXXXXXXXXXXXXXVLVFMDSHCTVGVKWLPPLLEPIKENYKTVTCPFIDINDTDTSLYSQDEG---ARGAFDWN--FNYTRLP-RLHNNKTDPEDPFDNPIMQGRIFAITRKWFWELGGYDEGLEIWGGEQFELSFKIWMCGGRMVNVPCSRIRCIFKDIYSFDFIHDDIKIRKNYKRIAEIWMDNWKKFIYQRHLEEYSSFDCGDISXXXXXXXXXNCKSFDWFMENVAYDILYLYPPITVSEKLNCSITLESDDSICVDSKYRKQGDRVGIDQCNQIGRSEKNKEQRFSFTSDFEIRPGQRNLCFDYRNSSETLMLSQCDLMNPNQKWEYNSTSHQITNIPSQKCI 1638
            N +  + +S++RT+      +CK  ++N+ LP  S+II F++  W  L++T   +L R+P  L++E++++DD +D +  +  +  Y+S+    V+++   KREGLI+ARL GA +A G+VL ++DSHC     W+ PLL+ IK +  TV CP ID+ D +T  Y   +    + G FDW   FN+  +P R   N+T P DP  +P M G +F+I +K+F +LG YD G +IWGGE  ELSFKIWMCGG +  VPCS +  +F+    + +      +++N  R+AE+W+D++K + Y+R   +   F  GDIS +KKL++ L CKSF W+++N+  ++      +   E  N        +  C+D K    G  VG+ QC+  G +     Q +  + D EIR  +   C DY  S   +M+  C  M  NQ+W YN  + ++ +  SQKC+
Sbjct:  144 NQYASDMISVHRTLPTNIDAECKTEKYNENLPRTSVIICFHNEAWSVLLRTVHSVLERTPDHLLEEVVLVDDFSDMDHTKRPLEEYMSQFGGKVKILRMEKREGLIRARLRGAAVATGEVLTYLDSHCECMEGWMEPLLDRIKRDPTTVVCPVIDVIDDNTFEYHHSKAYFTSVGGFDWGLQFNWHSIPERDRKNRTRPIDPVRSPTMAGGLFSIDKKYFEKLGTYDPGFDIWGGENLELSFKIWMCGGTLEIVPCSHVGHVFRKRSPYKWRTGVNVLKRNSIRLAEVWLDDYKTYYYERINNQLGDF--GDISSRKKLREDLGCKSFKWYLDNIYPELFVPGESVAKGEMRNAG----GKNRQCIDYK-PSGGKTVGMYQCHNQGGN-----QYWMLSKDGEIR--RDESCVDYAGSD--VMVFPCHGMKGNQEWRYNHDTGRLQHAVSQKCL 581          

Query:  295 NSFEEEKVSLYRTINELKITKCKWLRHNKTLPSVSIIITFYDSDWEXXXXXXXXXXXXSPRRLIKEXXXXXXXXXXXXMRSKMNAYISKNFTNVRVVHKTKREXXXXXXXXXXXXXXXXVLVFMDSHCTVGVKWLPPLLEPIKENYKTVTCPFIDINDTDTSLYSQDEG---ARGAFDWN--FNYTRLP-RLHNNKTDPEDPFDNPIMQGRIFAITRKWFWELGGYDEGLEIWGGEQFELSFKIWMCGGRMVNVPCSRIRCIFKDIYSFDFIHDDIKIRKNYKRIAEIWMDNWKKFIYQRHLEEYSSFDCGDISXXXXXXXXXNCKSFDWFMENVAYDILYLYPPITVSEKLNCSITLESDDSICVDSKYRKQGDRVGIDQCNQIGRSEKNKEQRFSFTSDFEIRPGQRNLCFDYRNSSETLMLSQCDLMNPNQKWEYNSTSHQITNIPSQKCI 1638
            N +  + +S++RT+      +CK  ++N+ LP  S+II F++  W  L++T   +L R+P  L++E++++DD +D +  +  +  Y+S+    V+++   KREGLI+ARL GA +A G+VL ++DSHC     W+ PLL+ IK +  TV CP ID+ D +T  Y   +    + G FDW   FN+  +P R   N+T P DP  +P M G +F+I +K+F +LG YD G +IWGGE  ELSFKIWMCGG +  VPCS +  +F+    + +      +++N  R+AE+W+D++K + Y+R   +   F  GDIS +KKL++ L CKSF W+++N+  ++      +   E  N        +  C+D K    G  VG+ QC+  G +     Q +  + D EIR  +   C DY  S   +M+  C  M  NQ+W YN  + ++ +  SQKC+
Sbjct:  144 NQYASDMISVHRTLPTNIDAECKTEKYNENLPRTSVIICFHNEAWSVLLRTVHSVLERTPDHLLEEVVLVDDFSDMDHTKRPLEEYMSQFGGKVKILRMEKREGLIRARLRGAAVATGEVLTYLDSHCECMEGWMEPLLDRIKRDPTTVVCPVIDVIDDNTFEYHHSKAYFTSVGGFDWGLQFNWHSIPERDRKNRTRPIDPVRSPTMAGGLFSIDKKYFEKLGTYDPGFDIWGGENLELSFKIWMCGGTLEIVPCSHVGHVFRKRSPYKWRTGVNVLKRNSIRLAEVWLDDYKTYYYERINNQLGDF--GDISSRKKLREDLGCKSFKWYLDNIYPELFVPGESVAKGEMRNAG----GKNRQCIDYK-PSGGKTVGMYQCHNQGGN-----QYWMLSKDGEIR--RDESCVDYAGSD--VMVFPCHGMKGNQEWRYNHDTGRLQHAVSQKCL 581          

Query:  295 NSFEEEKVSLYRTINELKITKCKWLRHNKTLPSVSIIITFYDSDWEXXXXXXXXXXXXSPRRLIKEXXXXXXXXXXXXMRSKMNAYISKNFTNVRVVHKTKREXXXXXXXXXXXXXXXXVLVFMDSHCTVGVKWLPPLLEPIKENYKTVTCPFIDINDTDTSLYSQDEG---ARGAFDWN--FNYTRLP-RLHNNKTDPEDPFDNPIMQGRIFAITRKWFWELGGYDEGLEIWGGEQFELSFKIWMCGGRMVNVPCSRIRCIFKDIYSFDFIHDDIKIRKNYKRIAEIWMDNWKKFIYQRHLEEYSSFDCGDISXXXXXXXXXNCKSFDWFMENVAYDILYLYPPITVSEKLNCSITLESDDSICVDSKYRKQGDRVGIDQCNQIGRSEKNKEQRFSFTSDFEIRPGQRNLCFDYRNSSETLMLSQCDLMNPNQKWEYNSTSHQITNIPSQKCI 1638
            N +  + +S++RT+      +CK  ++N+ LP  S+II F++  W  L++T   +L R+P  L++E++++DD +D +  +  +  Y+S+    V+++   KREGLI+ARL GA +A G+VL ++DSHC     W+ PLL+ IK +  TV CP ID+ D +T  Y   +    + G FDW   FN+  +P R   N+T P DP  +P M G +F+I +K+F +LG YD G +IWGGE  ELSFKIWMCGG +  VPCS +  +F+    + +      +++N  R+AE+W+D++K + Y+R   +   F  GDIS +KKL++ L CKSF W+++N+  ++      +   E  N        +  C+D K    G  VG+ QC+  G +     Q +  + D EIR  +   C DY  S   +M+  C  M  NQ+W YN  + ++ +  SQKC+
Sbjct:  144 NQYASDMISVHRTLPTNIDAECKTEKYNENLPRTSVIICFHNEAWSVLLRTVHSVLERTPDHLLEEVVLVDDFSDMDHTKRPLEEYMSQFGGKVKILRMEKREGLIRARLRGAAVATGEVLTYLDSHCECMEGWMEPLLDRIKRDPTTVVCPVIDVIDDNTFEYHHSKAYFTSVGGFDWGLQFNWHSIPERDRKNRTRPIDPVRSPTMAGGLFSIDKKYFEKLGTYDPGFDIWGGENLELSFKIWMCGGTLEIVPCSHVGHVFRKRSPYKWRTGVNVLKRNSIRLAEVWLDDYKTYYYERINNQLGDF--GDISSRKKLREDLGCKSFKWYLDNIYPELFVPGESVAKGEMRNAG----GKNRQCIDYK-PSGGKTVGMYQCHNQGGN-----QYWMLSKDGEIR--RDESCVDYAGSD--VMVFPCHGMKGNQEWRYNHDTGRLQHAVSQKCL 581          

Query:  220 DQENIRNLSNINLMMKRMNSTRRFNNSFEEEKVSLYRTINELKITKCKWLRHNKTLPSVSIIITFYDSDWEXXXXXXXXXXXXSPRRLIKEXXXXXXXXXXXXMRSKMNAYISKNFTNVRVVHKTKREXXXXXXXXXXXXXXXXVLVFMDSHCTVGVKWLPPLLEPIKENYKTVTCPFIDIND-TDTSLYSQDEGARGAFDWNFNYTRLPRLHNNKTDPEDPFDNPIMQGRIFAITRKWFWELGGYDEGLEIWGGEQFELSFKIWMCGGRMVNVPCSRIRCIFKDIYSF-------DFIHDDIKIRKNYKRIAEIWMDNWKKFIYQRHLEEYSSFDCGDISXXXXXXXXXNCKSFDWFMENVAYDILYLYPPITVSEKLNCSITLESDDSICVDSKYRKQGDRVGIDQC-NQIGRSEKNKEQRFSFTSDFEIRPGQRNLCFDYR--NSSETLMLSQCDLMNPNQKWEYNSTSHQITN 1617
            D E+ R+L       KRM+    FN +   + +S+ R++ +++   C+   +   LP+VS+II FY+     LM++   L+ RSP  L+KEI+++DD++D   +  ++  YI+++F  VRVV   +R GLI AR  GA+ A  +VL+F+DSH      WLPPLLEPI  N +T  CPFID+ D T+    +QDEGARGAFDW F Y RLP L  +   P DPF +PIM G +FAI+R++FWELGGYDEGL+IWGGEQ+ELSFKIWMCGG M + PCSRI  I++   +        D++H      KNYKR+AE+WMD +K ++Y      Y S D GD+++QK ++ KLNCKSF WFME VA+D++  YPP+        ++    + ++C+D+  RK+ +++G+  C + I   ++ +    S+  D  +R  ++  C D +  +++  + L  C     NQ W Y+    Q+ +
Sbjct:  153 DDESQRDLE------KRMSLENGFN-ALLSDSISVNRSVPDIRHPLCRKKEYVAKLPTVSVIIIFYNEYLSVLMRSVHSLINRSPPELMKEIILVDDHSDREYLGKELETYIAEHFKWVRVVRLPRRTGLIGARAAGARNATAEVLIFLDSHVEANYNWLPPLLEPIALNKRTAVCPFIDVIDHTNFHYRAQDEGARGAFDWEFFYKRLPLLPEDLKHPADPFKSPIMAGGLFAISREFFWELGGYDEGLDIWGGEQYELSFKIWMCGGEMYDAPCSRIGHIYRGPRNHQPSPRKGDYLH------KNYKRVAEVWMDEYKNYLYSHGDGLYESVDPGDLTEQKAIRTKLNCKSFKWFMEEVAFDLMKTYPPVDPPSYAMGALQNVGNQNLCLDTLGRKKHNKMGMYACADNIKTPQRTQFWELSWKRDLRLR--RKKECLDVQIWDANAPVWLWDCHSQGGNQYWYYDYRHKQLKH 614          

Query:  220 DQENIRNLSNINLMMKRMNSTRRFNNSFEEEKVSLYRTINELKITKCKWLRHNKTLPSVSIIITFYDSDWEXXXXXXXXXXXXSPRRLIKEXXXXXXXXXXXXMRSKMNAYISKNFTNVRVVHKTKREXXXXXXXXXXXXXXXXVLVFMDSHCTVGVKWLPPLLEPIKENYKTVTCPFIDIND-TDTSLYSQDEGARGAFDWNFNYTRLPRLHNNKTDPEDPFDNPIMQGRIFAITRKWFWELGGYDEGLEIWGGEQFELSFKIWMCGGRMVNVPCSRIRCIFKDIYSF-------DFIHDDIKIRKNYKRIAEIWMDNWKKFIYQRHLEEYSSFDCGDISXXXXXXXXXNCKSFDWFMENVAYDILYLYPPITVSEKLNCSITLESDDSICVDSKYRKQGDRVGIDQC-NQIGRSEKNKEQRFSFTSDFEIRPGQRNLCFDYR--NSSETLMLSQCDLMNPNQKWEYNSTSHQITN 1617
            D E+ R+L       KRM+    FN +   + +S+ R++ +++   C+   +   LP+VS+II FY+     LM++   L+ RSP  L+KEI+++DD++D   +  ++  YI+++F  VRVV   +R GLI AR  GA+ A  +VL+F+DSH      WLPPLLEPI  N +T  CPFID+ D T+    +QDEGARGAFDW F Y RLP L  +   P DPF +PIM G +FAI+R++FWELGGYDEGL+IWGGEQ+ELSFKIWMCGG M + PCSRI  I++   +        D++H      KNYKR+AE+WMD +K ++Y      Y S D GD+++QK ++ KLNCKSF WFME VA+D++  YPP+        ++    + ++C+D+  RK+ +++G+  C + I   ++ +    S+  D  +R  ++  C D +  +++  + L  C     NQ W Y+    Q+ +
Sbjct:  153 DDESQRDLE------KRMSLENGFN-ALLSDSISVNRSVPDIRHPLCRKKEYVAKLPTVSVIIIFYNEYLSVLMRSVHSLINRSPPELMKEIILVDDHSDREYLGKELETYIAEHFKWVRVVRLPRRTGLIGARAAGARNATAEVLIFLDSHVEANYNWLPPLLEPIALNKRTAVCPFIDVIDHTNFHYRAQDEGARGAFDWEFFYKRLPLLPEDLKHPADPFKSPIMAGGLFAISREFFWELGGYDEGLDIWGGEQYELSFKIWMCGGEMYDAPCSRIGHIYRGPRNHQPSPRKGDYLH------KNYKRVAEVWMDEYKNYLYSHGDGLYESVDPGDLTEQKAIRTKLNCKSFKWFMEEVAFDLMKTYPPVDPPSYAMGALQNVGNQNLCLDTLGRKKHNKMGMYACADNIKTPQRTQFWELSWKRDLRLR--RKKECLDVQIWDANAPVWLWDCHSQGGNQYWYYDYRHKQLKH 614          

Query:  220 DQENIRNLSNINLMMKRMNSTRRFNNSFEEEKVSLYRTINELKITKCKWLRHNKTLPSVSIIITFYDSDWEXXXXXXXXXXXXSPRRLIKEXXXXXXXXXXXXMRSKMNAYISKNFTNVRVVHKTKREXXXXXXXXXXXXXXXXVLVFMDSHCTVGVKWLPPLLEPIKENYKTVTCPFIDIND-TDTSLYSQDEGARGAFDWNFNYTRLPRLHNNKTDPEDPFDNPIMQGRIFAITRKWFWELGGYDEGLEIWGGEQFELSFKIWMCGGRMVNVPCSRIRCIFKDIYSF-------DFIHDDIKIRKNYKRIAEIWMDNWKKFIYQRHLEEYSSFDCGDISXXXXXXXXXNCKSFDWFMENVAYDILYLYPPITVSEKLNCSITLESDDSICVDSKYRKQGDRVGIDQC-NQIGRSEKNKEQRFSFTSDFEIRPGQRNLCFDYR--NSSETLMLSQCDLMNPNQKWEYNSTSHQITN 1617
            D E+ R+L       KRM+    FN +   + +S+ R++ +++   C+   +   LP+VS+II FY+     LM++   L+ RSP  L+KEI+++DD++D   +  ++  YI+++F  VRVV   +R GLI AR  GA+ A  +VL+F+DSH      WLPPLLEPI  N +T  CPFID+ D T+    +QDEGARGAFDW F Y RLP L  +   P DPF +PIM G +FAI+R++FWELGGYDEGL+IWGGEQ+ELSFKIWMCGG M + PCSRI  I++   +        D++H      KNYKR+AE+WMD +K ++Y      Y S D GD+++QK ++ KLNCKSF WFME VA+D++  YPP+        ++    + ++C+D+  RK+ +++G+  C + I   ++ +    S+  D  +R  ++  C D +  +++  + L  C     NQ W Y+    Q+ +
Sbjct:  153 DDESQRDLE------KRMSLENGFN-ALLSDSISVNRSVPDIRHPLCRKKEYVAKLPTVSVIIIFYNEYLSVLMRSVHSLINRSPPELMKEIILVDDHSDREYLGKELETYIAEHFKWVRVVRLPRRTGLIGARAAGARNATAEVLIFLDSHVEANYNWLPPLLEPIALNKRTAVCPFIDVIDHTNFHYRAQDEGARGAFDWEFFYKRLPLLPEDLKHPADPFKSPIMAGGLFAISREFFWELGGYDEGLDIWGGEQYELSFKIWMCGGEMYDAPCSRIGHIYRGPRNHQPSPRKGDYLH------KNYKRVAEVWMDEYKNYLYSHGDGLYESVDPGDLTEQKAIRTKLNCKSFKWFMEEVAFDLMKTYPPVDPPSYAMGALQNVGNQNLCLDTLGRKKHNKMGMYACADNIKTPQRTQFWELSWKRDLRLR--RKKECLDVQIWDANAPVWLWDCHSQGGNQYWYYDYRHKQLKH 614          

Query:  295 NSFEEEKVSLYRTINELKITKCKWLRHNKTLPSVSIIITFYDSDWEXXXXXXXXXXXXSPRRLIKEXXXXXXXXXXXXMRSKMNAYISKNFTN-VRVVHKTKREXXXXXXXXXXXXXXXXVLVFMDSHCTVGVKWLPPLLEPIKENYKTVTCPFID-INDTDTSLYSQD-EGARGAFDWNFNYTRLPRLHNNKTDPEDPFDNPIMQGRIFAITRKWFWELGGYDEGLEIWGGEQFELSFKIWMCGGRMVNVPCSRIRCIFKD-IYSFDFIHDDIKIRKNYKRIAEIWMDNWKKFIYQRHLEEYSSFDCGDISXXXXXXXXXNCKSFDWFMENVAYDILYLYPPITVSEKLNCSITLESDDSICVDSKYRKQGDRVGIDQC-NQIGRSEKNKEQRFSFTSDFEIRPGQRNLCFDYRNS--SETLMLSQCDLMNPNQKWEYNSTSHQITN 1617
            N    +++S+ R++ +L++  CK  ++   LP++S+I  F++  + TL+++   ++ R+P  L+K+I+++DD ++ + ++  ++ Y+ ++F + V +V   +R+GLI AR+ GAK+A G+V+VF DSH  V   WLPPL+EPI  N K  TCP +D I+  D S +S + +GARG FDW   Y +LP L  +  D   P+ +P+M G +FAI   +FW+LGGYD+ L+IWGGEQ+ELSFKIWMCGG +++VPCSR+  IF+  +           + KN+KR+AE+WMD +K+++Y+R  + Y + D GD+++Q+ ++++L CKSF WFM  VA D L  +PP+         I   ++   C+D+  +   + VG+  C +     + N+    S   D  ++ G  ++C D      + T+ +  C     NQ W Y+  + ++ +
Sbjct:  147 NGLISDRISVNRSVPDLRLEACKTRKYLAKLPNISVIFIFFNEHFNTLLRSIYSVINRTPPELLKQIVLVDDGSEWDVLKQPLDDYVQQHFPHLVTIVRNPERQGLIGARIAGAKVAVGQVMVFFDSHIEVNYNWLPPLIEPIAINPKISTCPMVDTISHEDFSYFSGNKDGARGGFDWKMLYKQLPVLPEDALDKSMPYRSPVMMGGLFAINTDFFWDLGGYDDQLDIWGGEQYELSFKIWMCGGMLLDVPCSRVAHIFRGPMKPRGNPRGHNFVAKNHKRVAEVWMDEYKQYVYKRDPKTYDNLDAGDLTRQRGVRERLKCKSFHWFMTEVAPDFLVKFPPVEPPSYAAGIIQNVANPVYCLDNMGKSTEEAVGMFSCADNRTHPQPNQFWELSIFRDLRMK-GFDSVCLDVHEGPPNATVWMWSCHSQGGNQFWYYDRQTQRLVH 593          

Query:  295 NSFEEEKVSLYRTINELKITKCKWLRHNKTLPSVSIIITFYDSDWEXXXXXXXXXXXXSPRRLIKEXXXXXXXXXXXXMRSKMNAYISKNFTN-VRVVHKTKREXXXXXXXXXXXXXXXXVLVFMDSHCTVGVKWLPPLLEPIKENYKTVTCPFID-INDTDTSLYSQD-EGARGAFDWNFNYTRLPRLHNNKTDPEDPFDNPIMQGRIFAITRKWFWELGGYDEGLEIWGGEQFELSFKIWMCGGRMVNVPCSRIRCIFKD-IYSFDFIHDDIKIRKNYKRIAEIWMDNWKKFIYQRHLEEYSSFDCGDISXXXXXXXXXNCKSFDWFMENVAYDILYLYPPITVSEKLNCSITLESDDSICVDSKYRKQGDRVGIDQC-NQIGRSEKNKEQRFSFTSDFEIRPGQRNLCFDYRNS--SETLMLSQCDLMNPNQKWEYNSTSHQITN 1617
            N    +++S+ R++ +L++  CK  ++   LP++S+I  F++  + TL+++   ++ R+P  L+K+I+++DD ++ + ++  ++ Y+ ++F + V +V   +R+GLI AR+ GAK+A G+V+VF DSH  V   WLPPL+EPI  N K  TCP +D I+  D S +S + +GARG FDW   Y +LP L  +  D   P+ +P+M G +FAI   +FW+LGGYD+ L+IWGGEQ+ELSFKIWMCGG +++VPCSR+  IF+  +           + KN+KR+AE+WMD +K+++Y+R  + Y + D GD+++Q+ ++++L CKSF WFM  VA D L  +PP+         I   ++   C+D+  +   + VG+  C +     + N+    S   D  ++ G  ++C D      + T+ +  C     NQ W Y+  + ++ +
Sbjct:  147 NGLISDRISVNRSVPDLRLEACKTRKYLAKLPNISVIFIFFNEHFNTLLRSIYSVINRTPPELLKQIVLVDDGSEWDVLKQPLDDYVQQHFPHLVTIVRNPERQGLIGARIAGAKVAVGQVMVFFDSHIEVNYNWLPPLIEPIAINPKISTCPMVDTISHEDFSYFSGNKDGARGGFDWKMLYKQLPVLPEDALDKSMPYRSPVMMGGLFAINTDFFWDLGGYDDQLDIWGGEQYELSFKIWMCGGMLLDVPCSRVAHIFRGPMKPRGNPRGHNFVAKNHKRVAEVWMDEYKQYVYKRDPKTYDNLDAGDLTRQRGVRERLKCKSFHWFMTEVAPDFLVKFPPVEPPSYAAGIIQNVANPVYCLDNMGKSTEEAVGMFSCADNRTHPQPNQFWELSIFRDLRMK-GFDSVCLDVHEGPPNATVWMWSCHSQGGNQFWYYDRQTQRLVH 593          

Query:  295 NSFEEEKVSLYRTINELKITKCKWLRHNKTLPSVSIIITFYDSDWEXXXXXXXXXXXXSPRRLIKEXXXXXXXXXXXXMRSKMNAYISKNFTNVRVVHKTKREXXXXXXXXXXXXXXXXVLVFMDSHCTVGVKWLPPLLEPIKENYKTVTCPFIDINDTDTSLYSQDEG--ARGAFDWNFNYTRLP-RLHNNKTDPEDPFDNPIMQGRIFAITRKWFWELGGYDEGLEIWGGEQFELSFKIWMCGGRMVNVPCSRIRCIFKDIYSFDFIHDDIKIRKNYKRIAEIWMDNWKKFIYQRHLEEYSSFDCGDISXXXXXXXXXNCKSFDWFMENVAYDILYLYPPITVSEKLNCSITLESDDSICVDSKYRKQGDRVGIDQCNQIGRSEK-NKEQRFSFTSDFEIRPGQ----RNLCFDYRNSSETLMLSQCDLMNPNQKWEYNSTSHQITNIPSQKCIXXXXXXXXXXXXXXXXXXTMQKWIIQGCN 1725
            N +    ++L R++ +++   CK   + + LP+ SIII F++  W +L++T   +  R+P  LI EI+++DD +D   +++ +  Y+S+ F  VR+V   KREGLI+ RLLGA +A+G+VL F+DSHC   + WLPPLL+ I +N KT+ CP ID+ D +   Y    G   RGAFDW   Y R+P        DP DP+ +P+M G +FA+ R+WFWELGGYD GLEIWGGEQFE+SFK+WMCGG M +VPCSR+  I++    +  +     + +N KR+AE WMD + ++IYQR   EY     GD++ QK+L++ L CK F W+M  VA+D+   YPP+         I   +   +CVDSK+   G  + +D C + G       EQ F+F    +IRPG     R  CFD  + +  + L  C  M  NQ W Y      + ++ S  C+  +     + +N C   S  Q+WI Q  N
Sbjct:  108 NIYVSNNIALDRSLPDIRHPNCKQKLYLENLPNTSIIIPFHNEGWSSLLRTLHSISNRTPDHLIAEIILVDDYSDREHLKAHLAEYMSR-FPKVRIVRTKKREGLIRTRLLGASVARGEVLTFLDSHCEANINWLPPLLDQIAQNPKTIVCPMIDVIDHNHFGYEAQAGDAMRGAFDWEMYYKRIPIPPELQGPDPSDPYQSPVMAGGLFAVNRQWFWELGGYDTGLEIWGGEQFEISFKVWMCGGSMYDVPCSRVGHIYRKYVPYK-VPSGTSLARNLKRVAETWMDEYTEYIYQRR-PEYRHLSTGDLTAQKELRKHLKCKDFKWYMNTVAWDLPKYYPPVEPLPAAWGEIR-NAASGLCVDSKHGSTGTELRLDNCLKEGAERTWAHEQIFTFGWREDIRPGDPLHTRKFCFDAISQNSPITLYDCHGMKGNQHWSYRKDK-SLYHLVSSGCMDCSPNDKRIFMNKCDPKSETQQWIFQKVN 587          

Query:  295 NSFEEEKVSLYRTINELKITKCKWLRHNKTLPSVSIIITFYDSDWEXXXXXXXXXXXXSPRRLIKEXXXXXXXXXXXXMRSKMNAYISKNFTNVRVVHKTKREXXXXXXXXXXXXXXXXVLVFMDSHCTVGVKWLPPLLEPIKENYKTVTCPFIDINDTDTSLYSQDEG--ARGAFDWNFNYTRLP-RLHNNKTDPEDPFDNPIMQGRIFAITRKWFWELGGYDEGLEIWGGEQFELSFKIWMCGGRMVNVPCSRIRCIFKDIYSFDFIHDDIKIRKNYKRIAEIWMDNWKKFIYQRHLEEYSSFDCGDISXXXXXXXXXNCKSFDWFMENVAYDILYLYPPITVSEKLNCSITLESDDSICVDSKYRKQGDRVGIDQCNQIGRSEK-NKEQRFSFTSDFEIRPGQ----RNLCFDYRNSSETLMLSQCDLMNPNQKWEYNSTSHQITNIPSQKCIXXXXXXXXXXXXXXXXXXTMQKWIIQGCN 1725
            N +    ++L R++ +++   CK   + + LP+ SIII F++  W +L++T   +  R+P  LI EI+++DD +D   +++ +  Y+S+ F  VR+V   KREGLI+ RLLGA +A+G+VL F+DSHC   + WLPPLL+ I +N KT+ CP ID+ D +   Y    G   RGAFDW   Y R+P        DP DP+ +P+M G +FA+ R+WFWELGGYD GLEIWGGEQFE+SFK+WMCGG M +VPCSR+  I++    +  +     + +N KR+AE WMD + ++IYQR   EY     GD++ QK+L++ L CK F W+M  VA+D+   YPP+         I   +   +CVDSK+   G  + +D C + G       EQ F+F    +IRPG     R  CFD  + +  + L  C  M  NQ W Y      + ++ S  C+  +     + +N C   S  Q+WI Q  N
Sbjct:  108 NIYVSNNIALDRSLPDIRHPNCKQKLYLENLPNTSIIIPFHNEGWSSLLRTLHSISNRTPDHLIAEIILVDDYSDREHLKAHLAEYMSR-FPKVRIVRTKKREGLIRTRLLGASVARGEVLTFLDSHCEANINWLPPLLDQIAQNPKTIVCPMIDVIDHNHFGYEAQAGDAMRGAFDWEMYYKRIPIPPELQGPDPSDPYQSPVMAGGLFAVNRQWFWELGGYDTGLEIWGGEQFEISFKVWMCGGSMYDVPCSRVGHIYRKYVPYK-VPSGTSLARNLKRVAETWMDEYTEYIYQRR-PEYRHLSTGDLTAQKELRKHLKCKDFKWYMNTVAWDLPKYYPPVEPLPAAWGEIR-NAASGLCVDSKHGSTGTELRLDNCLKEGAERTWAHEQIFTFGWREDIRPGDPLHTRKFCFDAISQNSPITLYDCHGMKGNQHWSYRKDK-SLYHLVSSGCMDCSPNDKRIFMNKCDPKSETQQWIFQKVN 587          

Query:  565 FTNVRVVHKTKREXXXXXXXXXXXXXXXXVLVFMDSHCTVGVKWLPPLLEPIKENYKTVTCPFIDINDTDTSLYSQDEG--ARGAFDWNFNYTRLP-RLHNNKTDPEDPFDNPIMQGRIFAITRKWFWELGGYDEGLEIWGGEQFELSFKIWMCGGRMVNVPCSRIRCIFKDIYSFDFIHDDIKIRKNYKRIAEIWMDNWKKFIYQRHLEEYSSFDCGDISXXXXXXXXXNCKSFDWFMENVAYDILYLYPPITVSEKLNCSITLESDDSICVDSKYRKQGDRVGIDQC-NQIGRSEKNKEQRFSFTSDFEIRPGQ----RNLCFDYRNSSETLMLSQCDLMNPNQKWEY---NSTSHQITNIPSQKCIXXXXXXXXXXXXXXXXXXTMQKWIIQGCNDN 1731
               VR++   KREGLI+ RLLGA  A+G+V+ F+DSHC   V WLPPLL+ I +N KT+ CP ID+ D D   Y    G   RGAFDW   Y R+P      K DP +PFD+P+M G +FA+ RKWFWELGGYD GLEIWGGEQ+E+SFK+WMCGGRM ++PCSR+  I++    +  +   + + +N KR+AE+WMD + +F+YQR   EY     GD+S+QK+L+ +L+C+SF WFME VA+D+   YPP+         +       +CV+SK+   G  + ++ C    G    +  Q F+F    +IR G     + +CFD  + +  + L  C  M  NQ W Y    S  H I+N     C+  ++    LL+++C  SS+ Q+W+ Q  N +
Sbjct:    4 LPKVRILRTQKREGLIRTRLLGAAAARGQVITFLDSHCEANVNWLPPLLDRIAQNRKTIVCPMIDVIDHDNFGYETQAGDAMRGAFDWEMYYKRIPIPAQLAKPDPSEPFDSPVMAGGLFAVDRKWFWELGGYDTGLEIWGGEQYEISFKVWMCGGRMEDIPCSRVGHIYRKYVPYK-VPGGVSLARNLKRVAEVWMDEYAEFLYQRR-PEYRHLSSGDVSQQKELRSRLHCRSFRWFMEEVAWDLPKHYPPVEPPAAAWGELR-NVGTGLCVESKHFSSGSPIRLEPCLRSRGEPSWSHGQVFTFGWRQDIRVGDPLHTKKVCFDAVSHNSPVTLYDCHGMKGNQLWAYRKDRSLFHPISN----SCVSADAAQKRLLMSSCDASSSSQQWVFQNTNSS 396          

Query:  262 MKRMNSTRRFNNSFEEEKVSLYRTINELKITKCKWLRHNKTLPSVSIIITFYDSDWEXXXXXXXXXXXXSPRRLIKEXXXXXXXXXXXXMRSKMNAYISKNFTNVRVVHKTKREXXXXXXXXXXXXXXXXVLVFMDSHCTVGVKWLPPLLEPIKENYKTVTCPFIDINDTDTSLY-SQDEGARGAFDWNFNYTRLP----RLHNNKTDPEDPFDNPIMQGRIFAITRKWFWELGGYDEGLEIWGGEQFELSFKIWMCGGRMVNVPCSRIRCIFKDIYSFDFIHDDIK-IRKNYKRIAEIWMDNWKKFIYQRHLEEYSSFDCGDISXXXXXXXXXNCKSFDWFMENVAYDILYLYPPITVSEKLNCSITLESDDSICVDSKYRKQGDRVGIDQCNQIGRSEKNKEQRFSFTSDFEIRPGQRNLCFDYRNSSETLMLSQCDLMNPNQKWEYNSTSHQITNIPSQKCI 1638
            MK M    +FN     E ++L R++ ++++  CK   +   LP  S++I F++  W TL++T   ++ RSPR L++EI+++DD ++ + ++ ++  Y+ K    VRVV   +R GLI+ARL GA ++ G+V+ F+D+HC     WL PLL  IK + KTV CP ID+   DT  Y +  +   G F+W  N+   P     +   K D   P   P M G +F+I R +F E+G YD G++IWGGE  E+SF+IW CGG +  V CS +  +F+    + F     + I KN +R+AE+WMD +K F Y       +  D GDIS +  L+Q+L CK F W++ENV  D        ++ E  N       + + C+D+  RK+ ++VGI  C+ +G       Q FS+T++ EIR    +LC D    +  +M+ +C  +  NQ WEY+     + ++ S +C+
Sbjct:   73 MKEMFKINQFN-LMASEMIALNRSLPDVRLEGCKTKVYPDDLPRTSVVIVFHNEAWTTLLRTVHSVIDRSPRHLLEEIVLVDDASERDFLKRQLEHYVRKLEVPVRVVRMEQRSGLIRARLKGASISTGQVITFLDAHCECTTGWLEPLLSRIKLDKKTVVCPIIDVISDDTFEYMAGSDMTYGGFNWKLNFRWYPVPQREMDRRKGDRTLPVRTPTMAGGLFSIDRDYFQEIGTYDAGMDIWGGENLEISFRIWQCGGTLEIVTCSHVGHVFRKATPYTFPGGTGQIINKNNRRLAEVWMDEFKNFFYIIS-PGVTKVDYGDISTRTSLRQRLQCKPFSWYLENVYPDSQIPRHYYSLGEIRNV------ETNQCLDNMARKENEKVGIFNCHGMG-----GNQVFSYTANKEIR--TDDLCLDVSKLNGPVMMLKCHHLKGNQLWEYDPVKLSLVHVNSNQCL 522          

Query:  262 MKRMNSTRRFNNSFEEEKVSLYRTINELKITKCKWLRHNKTLPSVSIIITFYDSDWEXXXXXXXXXXXXSPRRLIKEXXXXXXXXXXXXMRSKMNAYISKNFTNVRVVHKTKREXXXXXXXXXXXXXXXXVLVFMDSHCTVGVKWLPPLLEPIKENYKTVTCPFIDINDTDTSLY-SQDEGARGAFDWNFNYTRLP----RLHNNKTDPEDPFDNPIMQGRIFAITRKWFWELGGYDEGLEIWGGEQFELSFKIWMCGGRMVNVPCSRIRCIFKDIYSFDFIHDDIK-IRKNYKRIAEIWMDNWKKFIYQRHLEEYSSFDCGDISXXXXXXXXXNCKSFDWFMENVAYDILYLYPPITVSEKLNCSITLESDDSICVDSKYRKQGDRVGIDQCNQIGRSEKNKEQRFSFTSDFEIRPGQRNLCFDYRNSSETLMLSQCDLMNPNQKWEYNSTSHQITNIPSQKCI 1638
            MK M    +FN     E ++L R++ ++++  CK   +   LP  S++I F++  W TL++T   ++ RSPR L++EI+++DD ++ + ++ ++  Y+ K    VRVV   +R GLI+ARL GA ++ G+V+ F+D+HC     WL PLL  IK + KTV CP ID+   DT  Y +  +   G F+W  N+   P     +   K D   P   P M G +F+I R +F E+G YD G++IWGGE  E+SF+IW CGG +  V CS +  +F+    + F     + I KN +R+AE+WMD +K F Y       +  D GDIS +  L+Q+L CK F W++ENV  D        ++ E  N       + + C+D+  RK+ ++VGI  C+ +G       Q FS+T++ EIR    +LC D    +  +M+ +C  +  NQ WEY+     + ++ S +C+
Sbjct:   73 MKEMFKINQFN-LMASEMIALNRSLPDVRLEGCKTKVYPDDLPRTSVVIVFHNEAWTTLLRTVHSVIDRSPRHLLEEIVLVDDASERDFLKRQLEHYVRKLEVPVRVVRMEQRSGLIRARLKGASISTGQVITFLDAHCECTTGWLEPLLSRIKLDKKTVVCPIIDVISDDTFEYMAGSDMTYGGFNWKLNFRWYPVPQREMDRRKGDRTLPVRTPTMAGGLFSIDRDYFQEIGTYDAGMDIWGGENLEISFRIWQCGGTLEIVTCSHVGHVFRKATPYTFPGGTGQIINKNNRRLAEVWMDEFKNFFYIIS-PGVTKVDYGDISTRTSLRQRLQCKPFSWYLENVYPDSQIPRHYYSLGEIRNV------ETNQCLDNMARKENEKVGIFNCHGMG-----GNQVFSYTANKEIR--TDDLCLDVSKLNGPVMMLKCHHLKGNQLWEYDPVKLSLVHVNSNQCL 522          

Query:  295 NSFEEEKVSLYRTINELKITKCKWLRHNKTLPSVSIIITFYDSDWEXXXXXXXXXXXXSPRRLIKEXXXXXXXXXXXXMRSKMNAYISKNFTNVRVVHKTKREXXXXXXXXXXXXXXXXVLVFMDSHCTVGVKWLPPLLEPIKENYKTVTCPFIDINDTDTSLYSQDEG--ARGAFDWNFNYTRLP-RLHNNKTDPEDPFDNPIMQGRIFAITRKWFWELGGYDEGLEIWGGEQFELSFKIWMCGGRMVNVPCSRIRCIFKDIYSFDFIHDDIKIRKNYKRIAEIWMDNWKKFIYQRHLEEYSSFDCGDISXXXXXXXXXNCKSFDWFMENVAYDILYLYPPITVSEKLNCSITLESDDSICVDSKYRKQGDRVGIDQCNQIGRSEK--NKEQRFSFTSDFEIRPGQ----RNLCFDYRNSSETLMLSQCDLMNPNQKWEY---NSTSHQITNIPSQKCIXXXXXXXXXXXXXXXXXXTMQKWIIQGCN 1725
            N F   K++L R++ +++   CK   + + LP+ SIII F++  W +L++T   ++ R+P  LI+E++++DD +D   +R K+  Y++  +  VR+V   KREGLI+ RLLGA +AKG+VL F+DSHC V V WLPPLL  I  N+KT+ CP ID+ D +   Y    G   RGAFDW   Y R+P      +TDP +PF++P+M G +FA+ RKWFWELGGYD GLEIWGGEQ+ELSFK+WMCGG M +VPCSR+  I++    +  +     + +N KR+AE WMD + ++IYQR   EY     GDIS QK+L++ L CK F W+M  VA+D+   YPP+         I      ++C+DSK+   G  + +D C + G SE+  + EQ F+F    +IRPG+    R  CFD  + S  + L  C  M  NQ+W Y    +  H +TN     CI  N     L +N C   S  Q+WI +  N
Sbjct:  108 NIFVSNKIALARSLPDIRHPNCKHKLYLERLPNTSIIIPFHNEGWTSLLRTIHSVINRTPDSLIEEMILVDDFSDREHLREKLEEYMA-YYPKVRIVRTKKREGLIRTRLLGASMAKGEVLTFLDSHCEVNVNWLPPLLNQIALNHKTIVCPMIDVIDHNHFGYEAQAGDAMRGAFDWEMYYKRIPIPPELQRTDPSEPFESPVMAGGLFAVDRKWFWELGGYDPGLEIWGGEQYELSFKVWMCGGEMFDVPCSRVGHIYRKYVPYK-VPTGTSLARNLKRVAETWMDEYAEYIYQRR-PEYRHLSTGDISSQKELRKHLKCKDFKWYMSEVAWDVPKFYPPVEPPPASWGEIR-NVASNLCIDSKHGATGTELRLDTCVKDG-SERTWSHEQLFTFGWREDIRPGEPLHTRKFCFDSISHSSPVTLYDCHGMKGNQQWSYRKDKTLFHPVTN----SCIDCNPAEKKLFMNRCDPLSETQQWIFEHVN 587          

Query:  295 NSFEEEKVSLYRTINELKITKCKWLRHNKTLPSVSIIITFYDSDWEXXXXXXXXXXXXSPRRLIKEXXXXXXXXXXXXMRSKMNAYISKNFTNVRVVHKTKREXXXXXXXXXXXXXXXXVLVFMDSHCTVGVKWLPPLLEPIKENYKTVTCPFIDINDTDTSLYSQDEG--ARGAFDWNFNYTRLP-RLHNNKTDPEDPFDNPIMQGRIFAITRKWFWELGGYDEGLEIWGGEQFELSFKIWMCGGRMVNVPCSRIRCIFKDIYSFDFIHDDIKIRKNYKRIAEIWMDNWKKFIYQRHLEEYSSFDCGDISXXXXXXXXXNCKSFDWFMENVAYDILYLYPPITVSEKLNCSITLESDDSICVDSKYRKQGDRVGIDQCNQIGRSEKNKEQRFSFTSDF--EIRPG--QRNL--CFDYRNSSETLMLSQCDLMNPNQKWEY 1590
            N F  +K+SL R++ +++ + CK   +   LP+ S+II F++  W +L++T   +L RSP  LI EI+++DD +D   ++S++  Y++ NF  V++V   KREGLI+ R+LGA +A G+VL F+DSHC   V WLPPLL+P+ +NYKTV CP ID+ D+D   Y    G   RGAFDW   Y R+P      K DP DPFD+P+M G +FAI R+WFW+LGGYD GLEIWGGEQ+E+SFK+WMCGGRMV+ PCSR+  I++    +  +   + + +N KR+AE+WMD + ++IYQR   +Y     GD++ QK+L++KL C+ F WFM  +A+D+   YPP+ +       I     D +CV  K+   G  + ++ CN+ GR+      R  FT  +  +IRPG  Q  +  CFD  + +  + L  C  M  NQ W+Y
Sbjct:  111 NIFVSDKISLNRSLPDIRHSNCKNKFYFSKLPNTSVIIPFHNEGWSSLLRTVHSVLNRSPPELIAEIVLVDDYSDKAHLKSRLEKYMA-NFPKVKIVRTKKREGLIRTRMLGATVASGEVLTFLDSHCEANVNWLPPLLDPLVQNYKTVVCPMIDVIDSDNFGYVTQAGDAMRGAFDWEMFYKRIPIPPELQKGDPSDPFDSPVMAGGLFAINREWFWQLGGYDPGLEIWGGEQYEISFKVWMCGGRMVDSPCSRVGHIYRKYVPYK-VPAGVSLARNLKRVAEVWMDEYAEYIYQRR-PDYRHLSVGDVAAQKELRRKLQCRDFKWFMNEIAWDLPKYYPPVELPPAAWGEIRNVRMD-MCVGVKHVTSGTEIRLEACNK-GRNSDTWGARQVFTLGWREDIRPGIPQHTMKSCFDAVSQTSPVTLFDCHGMKGNQLWKY 546          

Query:  295 NSFEEEKVSLYRTINELKITKCKWLRHNKTLPSVSIIITFYDSDWEXXXXXXXXXXXXSPRRLIKEXXXXXXXXXXXXMRSKMNAYISKNFTNVRVVHKTKREXXXXXXXXXXXXXXXXVLVFMDSHCTVGVKWLPPLLEPIKENYKTVTCPFIDINDTDTSLYSQDEG--ARGAFDWNFNYTRLP-RLHNNKTDPEDPFDNPIMQGRIFAITRKWFWELGGYDEGLEIWGGEQFELSFKIWMCGGRMVNVPCSRIRCIFKDIYSFDFIHDDIKIRKNYKRIAEIWMDNWKKFIYQRHLEEYSSFDCGDISXXXXXXXXXNCKSFDWFMENVAYDILYLYPPITVSEKLNCSITLESDDSICVDSKYRKQGDRVGIDQCNQIGRSEKNKEQRFSFTSDF--EIRPG--QRNL--CFDYRNSSETLMLSQCDLMNPNQKWEY 1590
            N F  +K+SL R++ +++ + CK   +   LP+ S+II F++  W +L++T   +L RSP  LI EI+++DD +D   ++S++  Y++ NF  V++V   KREGLI+ R+LGA +A G+VL F+DSHC   V WLPPLL+P+ +NYKTV CP ID+ D+D   Y    G   RGAFDW   Y R+P      K DP DPFD+P+M G +FAI R+WFW+LGGYD GLEIWGGEQ+E+SFK+WMCGGRMV+ PCSR+  I++    +  +   + + +N KR+AE+WMD + ++IYQR   +Y     GD++ QK+L++KL C+ F WFM  +A+D+   YPP+ +       I     D +CV  K+   G  + ++ CN+ GR+      R  FT  +  +IRPG  Q  +  CFD  + +  + L  C  M  NQ W+Y
Sbjct:  111 NIFVSDKISLNRSLPDIRHSNCKNKFYFSKLPNTSVIIPFHNEGWSSLLRTVHSVLNRSPPELIAEIVLVDDYSDKAHLKSRLEKYMA-NFPKVKIVRTKKREGLIRTRMLGATVASGEVLTFLDSHCEANVNWLPPLLDPLVQNYKTVVCPMIDVIDSDNFGYVTQAGDAMRGAFDWEMFYKRIPIPPELQKGDPSDPFDSPVMAGGLFAINREWFWQLGGYDPGLEIWGGEQYEISFKVWMCGGRMVDSPCSRVGHIYRKYVPYK-VPAGVSLARNLKRVAEVWMDEYAEYIYQRR-PDYRHLSVGDVAAQKELRRKLQCRDFKWFMNEIAWDLPKYYPPVELPPAAWGEIRNVRMD-MCVGVKHVTSGTEIRLEACNK-GRNSDTWGARQVFTLGWREDIRPGIPQHTMKSCFDAVSQTSPVTLFDCHGMKGNQLWKY 546          

Query:  295 NSFEEEKVSLYRTINELKITKCKWLRHNKTLPSVSIIITFYDSDWEXXXXXXXXXXXXSPRRLIKEXXXXXXXXXXXXMRSKMNAYISKNFTNVRVVHKTKREXXXXXXXXXXXXXXXXVLVFMDSHCTVGVKWLPPLLEPIKENYKTVTCPFIDINDTDTSLYSQDEG--ARGAFDWNFNYTRLP-RLHNNKTDPEDPFDNPIMQGRIFAITRKWFWELGGYDEGLEIWGGEQFELSFKIWMCGGRMVNVPCSRIRCIFKDIYSFDFIHDDIKIRKNYKRIAEIWMDNWKKFIYQRHLEEYSSFDCGDISXXXXXXXXXNCKSFDWFMENVAYDILYLYPPITVSE------KLNCSITLESDDSICVDSKYRKQGDRVGIDQCNQIGRSEKNKEQRFSFTSDFEIRPGQ----RNLCFDYRNSSETLMLSQCDLMNPNQKWEY---NSTSHQITNIPSQKCIXXXXXXXXXXXXXXXXXXTMQKWIIQGCN 1725
            N F   K++L R++ +++   CK   + + LP+ SIII F++  W +L++T   ++ R+P  LI+E++++DD +D   +R K+  Y++  +  VR+V   KREGLI+ RLLGA +AKG+VL F+DSHC V V WLPPLL  I  N+KT+ CP ID+ D +   Y    G   RGAFDW   Y R+P      +TDP +PF++P+M G +FA+ RKWFWELGGYD GLEIWGGEQ+ELSFK+WMCGG M +VPCSR+  I++    +  +     + +N KR+AE WMD + ++IYQR   EY     GDIS QK+L++ L CK F W+M  VA+D+   YPP+          K+NC                                         F+F    +IRPG+    R  CFD  + S  + L  C  M  NQ+W Y    +  H +TN     CI  N     L +N C   S  Q+WI +  N
Sbjct:  108 NIFVSNKIALARSLPDIRHPNCKHKLYLERLPNTSIIIPFHNEGWTSLLRTIHSVINRTPDSLIEEMILVDDFSDREHLREKLEEYMA-YYPKVRIVRTKKREGLIRTRLLGASMAKGEVLTFLDSHCEVNVNWLPPLLNQIALNHKTIVCPMIDVIDHNHFGYEAQAGDAMRGAFDWEMYYKRIPIPPELQRTDPSEPFESPVMAGGLFAVDRKWFWELGGYDPGLEIWGGEQYELSFKVWMCGGEMFDVPCSRVGHIYRKYVPYK-VPTGTSLARNLKRVAETWMDEYAEYIYQRR-PEYRHLSTGDISSQKELRKHLKCKDFKWYMSEVAWDVPKFYPPVEPPPASWGEVKINC----------------------------------------LFTFGWREDIRPGEPLHTRKFCFDSISHSSPVTLYDCHGMKGNQQWSYRKDKTLFHPVTN----SCIDCNPAEKKLFMNRCDPLSETQQWIFEHVN 553          

Query:  295 NSFEEEKVSLYRTINELKITKCKWLRHNKTLPSVSIIITFYDSDWEXXXXXXXXXXXXSPRRLIKEXXXXXXXXXXXXMRSKMNAYISKNFTNVRVVHKTKREXXXXXXXXXXXXXXXXVLVFMDSHCTVGVKWLPPLLEPIKENYKTVTCPFIDINDTDTSLYSQDEG--ARGAFDWNFNYTRLPRLHN-NKTDPEDPFDNPIMQGRIFAITRKWFWELGGYDEGLEIWGGEQFELSFKIWMCGGRMVNVPCSRIRCIFKDIYSFDFIHDDIKIRKNYKRIAEIWMDNWKKFIYQRHLEEYSSFDCGDISXXXXXXXXXNCKSFDWFMENVAYDILYLYPPITVSE------KLNCSITLESDDSICVDSKYRKQGDRVGIDQCNQIGRSEKNKEQRFSFTSDFEIRPGQ----RNLCFDYRNSSETLMLSQCDLMNPNQKWEY 1590
            N F   K++L R++ +++   CK   + + LP+ SIII F++  W +L++T   ++ R+P  LI+E++++DD +D   +R K+  Y++  +  VR+V   KREGLI+ RLLGA +AKG+VL F+DSHC V V WLPPLL  I  N+KT+ CP ID+ D +   Y    G   RGAFDW   Y R+P      +TDP +PF++P+M G +FA+ RKWFWELGGYD GLEIWGGEQ+ELSFK+WMCGG M +VPCSR+  I++    +  +     + +N KR+AE WMD + ++IYQR   EY     GDIS QK+L++ L CK F W+M  VA+D+   YPP+          K+NC                                         F+F    +IRPG+    R  CFD  + S  + L  C  M  NQ+W Y
Sbjct:  108 NIFVSNKIALARSLPDIRHPNCKHKLYLERLPNTSIIIPFHNEGWTSLLRTIHSVINRTPDSLIEEMILVDDFSDREHLREKLEEYMA-YYPKVRIVRTKKREGLIRTRLLGASMAKGEVLTFLDSHCEVNVNWLPPLLNQIALNHKTIVCPMIDVIDHNHFGYEAQAGDAMRGAFDWEMYYKRIPIPPELQRTDPSEPFESPVMAGGLFAVDRKWFWELGGYDPGLEIWGGEQYELSFKVWMCGGEMFDVPCSRVGHIYRKYVPYK-VPTGTSLARNLKRVAETWMDEYAEYIYQRR-PEYRHLSTGDISSQKELRKHLKCKDFKWYMSEVAWDVPKFYPPVEPPPASWGEVKINC----------------------------------------LFTFGWREDIRPGEPLHTRKFCFDSISHSSPVTLYDCHGMKGNQQWSY 509          

Query:  265 KRMNSTRRFN--NSFEEEKVSLYRTINELKITKCKWLRHNKTLPSVSIIITFYDSDWEXXXXXXXXXXXXSPRRLIKEXXXXXXXXXXXXMRSKMNAYISKNFTNVRVVHKTKREXXXXXXXXXXXXXXXXVLVFMDSHCTVGVKWLPPLLEPIKENYKTVTCPFIDINDTDTSLYSQDEG--ARGAFDWNFNYTRLP-RLHNNKTDPEDPFDNPIMQGRIFAITRKWFWELGGYDEGLEIWGGEQFELSFKIWMCGGRMVNVPCSRIRCIFKDIYSFDFIHDDIKIRKNYKRIAEIWMDNWKKFIYQRHLEEYSSFDCGDISXXXXXXXXXNCKSFDWFMENVAYDILYLYPPITVSEKLNCSITLESDDSICVDSKYRKQGDRVGIDQCNQIGRSEK--NKEQRFSFTSDFEIRPGQ----RNLCFDYRNSSETLMLSQCDLMNPNQKWEY 1590
            +R++   R N  N +  +K+SL R++ +++   C    + +TLP+ SIII F++  W +L++T   +L RSP  L+ EI+++DD +D   ++  +  Y++  F +VR++   KREGLI+ R+LGA  A G V+ F+DSHC   V WLPPLL+ I  N KT+ CP ID+ D D   Y    G   RGAFDW   Y R+P      K DP DPF++P+M G +FA+ RKWFWELGGYD GLEIWGGEQ+E+SFK+WMCGGRM ++PCSR+  I++    +  +   + + +N KR+AE+WMD + ++IYQR   EY     GD+  QKKL+  LNCKSF WFM  +A+D+   YPP+         I       +C D+K    G  + ++ C + GR E   N  Q F+FT   +IRPG     +  CFD  + +  + L  C  M  NQ W+Y
Sbjct:  102 ERVDQAYRENGFNIYVSDKISLNRSLPDIRHPNCNSKLYLETLPNTSIIIPFHNEGWSSLLRTVHSVLNRSPPELVAEIVLVDDFSDREHLKKPLEDYMAL-FPSVRILRTKKREGLIRTRMLGASAATGDVVTFLDSHCEANVNWLPPLLDRIARNRKTIVCPMIDVIDHDDFRYETQAGDAMRGAFDWEMYYKRIPIPPELQKADPSDPFESPVMAGGLFAVDRKWFWELGGYDPGLEIWGGEQYEISFKVWMCGGRMEDIPCSRVGHIYRKYVPYK-VPAGVSLARNLKRVAEVWMDEYAEYIYQRR-PEYRHLSAGDVVAQKKLRVSLNCKSFKWFMTKIAWDLPKFYPPVEPPAAAWGEIR-NVGTGLCTDTKLGTLGSPLRLETCIR-GRGEAAWNSMQVFTFTWREDIRPGDPQHTKKFCFDAVSHTSPVTLYDCHSMKGNQLWKY 549          

Query:  268 RMNSTRRFN--NSFEEEKVSLYRTINELKITKCKWLRHNKTLPSVSIIITFYDSDWEXXXXXXXXXXXXSPRRLIKEXXXXXXXXXXXXMRSKMNAYISKNFTNVRVVHKTKREXXXXXXXXXXXXXXXXVLVFMDSHCTVGVKWLPPLLEPIKENYKTVTCPFIDINDTDTSLYSQDEG--ARGAFDWNFNYTRLP-RLHNNKTDPEDPFDNPIMQGRIFAITRKWFWELGGYDEGLEIWGGEQFELSFKIWMCGGRMVNVPCSRIRCIFKDIYSFDFIHDDIKIRKNYKRIAEIWMDNWKKFIYQRHLEEYSSFDCGDISXXXXXXXXXNCKSFDWFMENVAYDILYLYPPITVSEKLNCSITLESDDSICVDSKYRKQGDRVGIDQCNQIGRSEK--NKEQRFSFTSDFEIRPGQ----RNLCFDYRNSSETLMLSQCDLMNPNQKWEY---NSTSHQITNI-----PSQKCI 1638
            R +S  R N  N F    ++L R++ +++   CK   + + LP+ SIII F++  W +L++T   ++ R+P  LI EI+++DD +D   ++ K+  Y+++ F+ VR+V   KREGLI+ RLLGA +A+G+VL F+DSHC V V WLPPLL  I  N+KT+ CP ID+ D +   Y    G   RGAFDW   Y R+P      + DP DPF++P+M G +FA+ RKWFWELGGYD GLEIWGGEQ+E+SFK+WMCGG M +VPCSR+  I++    +  +     + +N KR+AE WMD + ++IYQR   EY     GDIS QK+L+++L CK F WFM  VA+D+   YPP+         I   + + +CVDSK+   G  + +D C + G SE+  + EQ F+F    +IRPG+    R  C D  + S  + L  C  M  NQ W Y    +  H ++N      PS+K I
Sbjct:   98 RDDSAYRENGFNIFVSNNIALERSLPDIRHANCKHKMYLERLPNTSIIIPFHNEGWTSLLRTIHSIINRTPESLIAEIILVDDFSDREHLKDKLEDYMAR-FSKVRIVRTKKREGLIRTRLLGASVARGEVLTFLDSHCEVNVNWLPPLLNQIALNHKTIVCPMIDVIDHNHFGYEAQAGDAMRGAFDWEMYYKRIPIPPELQRADPSDPFESPVMAGGLFAVDRKWFWELGGYDPGLEIWGGEQYEISFKVWMCGGEMFDVPCSRVGHIYRKYVPYK-VPSGTSLARNLKRVAETWMDEFAEYIYQRR-PEYRHLSTGDISAQKELRKRLKCKDFKWFMAAVAWDVPKYYPPVEPLPAAWGEIRSVAAN-LCVDSKHGATGTELRLDVCVKDG-SERTWSHEQLFTFGWREDIRPGEPLHTRKFCLDAISHSSPVTLYDCHGMKGNQLWGYREDRTLFHPVSNSCMDCNPSEKKI 568          

Query:  529 MRSKMNAYISKNFTNVRVVHKTKREXXXXXXXXXXXXXXXXVLVFMDSHCTVGVKWLPPLLEPIKENYKTVTCPFIDINDTDTSLYSQDEG--ARGAFDWNFNYTRLP-RLHNNKTDPEDPFDNPIMQGRIFAITRKWFWELGGYDEGLEIWGGEQFELSFKIWMCGGRMVNVPCSRIRCIFKDIYSFDFIHDDIKIRKNYKRIAEIWMDNWKKFIYQRHLEEYSSFDCGDISXXXXXXXXXNCKSFDWFMENVAYDILYLYPPITVSEKLNCSITLESDDSICVDSKYRKQGDRVGIDQCNQIGRSEK--NKEQRFSFTSDFEIRPGQ----RNLCFDYRNSSETLMLSQCDLMNPNQKWEY---NSTSHQITNI-----PSQKCI 1638
            ++ K+  Y+++ F+ VR+V   KREGLI+ RLLGA +A+G+VL F+DSHC V V WLPPLL  I  N+KT+ CP ID+ D +   Y    G   RGAFDW   Y R+P      + DP DPF++P+M G +FA+ RKWFWELGGYD GLEIWGGEQ+E+SFK+WMCGG M +VPCSR+  I++    +  +     + +N KR+AE WMD + ++IYQR   EY     GDIS QK+L+++L CK F WFM  VA+D+   YPP+         I   + + +CVDSK+   G  + +D C + G SE+  + EQ F+F    +IRPG+    R  C D  + S  + L  C  M  NQ W Y    +  H ++N      PS+K I
Sbjct:    3 LKDKLEDYMAR-FSKVRIVRTKKREGLIRTRLLGASVARGEVLTFLDSHCEVNVNWLPPLLNQIALNHKTIVCPMIDVIDHNHFGYEAQAGDAMRGAFDWEMYYKRIPIPPELQRADPSDPFESPVMAGGLFAVDRKWFWELGGYDPGLEIWGGEQYEISFKVWMCGGEMFDVPCSRVGHIYRKYVPYK-VPSGTSLARNLKRVAETWMDEFAEYIYQRR-PEYRHLSTGDISAQKELRKRLKCKDFKWFMAAVAWDVPKYYPPVEPLPAAWGEIRSVAAN-LCVDSKHGATGTELRLDVCVKDG-SERTWSHEQLFTFGWREDIRPGEPLHTRKFCLDAISHSSPVTLYDCHGMKGNQLWGYREDRTLFHPVSNSCMDCNPSEKKI 384          

Query:  295 NSFEEEKVSLYRTINELKITKCKWLRHNKTLPSVSIIITFYDSDWEXXXXXXXXXXXXSPRRLIKEXXXXXXXXXXXXMRSKMNAYISKNFTNVRVVHKTKREXXXXXXX-XXXXXXXXXVLVFMDSHCTVGVKWLPPLLEPIKENYKTVTCPFID-INDTDTSLYSQDEG-----ARGAFDWNFNYTRLPRLHNNKTDPE---DPFDNPIMQGRIFAITRKWFWELGGYDEGLEIWGGEQFELSFKIWMCGGRMVNVPCSRIRCIFK----DIYSFDFIHDDIKIRKNYKRIAEIWMDNWKKFIYQRHLEEYSSFDCGDISXXXXXXXXXNCKSFDWFMENVAYDILYLYPPITVSEKLNCSITLESDDSICVDSKYRKQGDRVGIDQCNQIGRSEKNKEQRFSFTSDFEIRPGQRNLCFDYRNSSETLMLSQCDLMNPNQKWEYNSTSHQITNIPSQKCIXXXXXXXXXXXXXXXXXXTMQKW 1707
            N    + +SL R++N+L+  +CK+  +++ L + S++I F++  W TLM+T   ++ R+PR+ + EI++IDD ++   ++ K++ YI      V+V    +REGLI+AR     K   G+VL+++D+HC V V W  PL+ PI ++  T T P ID I+  D S+  Q  G     ARGA+DW+  + R+P  H  K   +   +P+ +P M G +FAI + +F+ELG YD GL+IWGGE FE+S+KIW CGG+++ VPCSR+  I++                   KNY R+ E+W D +K + Y     E  +   GDIS+ KK ++  NCKSF WFME +AYDI   YP    + +      LE+  + C+DS  +  G  V +  C+++G +     Q F      ++   Q + C         +M++ C+L N  ++W+Y  + H+ T+I S KC+  +     + ++ C  S   QKW
Sbjct:  176 NMVASDMISLDRSVNDLRQEECKYWHYDENLLTSSVVIVFHNEGWSTLMRTVHSVIKRTPRKYLAEIVLIDDFSNKEHLKEKLDEYIKLWNGLVKVFRNERREGLIQARSIGAQKAKLGQVLIYLDAHCEVAVNWYAPLVAPISKDRATCTVPLIDYIDGNDYSIEPQQGGDEDGFARGAWDWSMLWKRIPLSHKEKAKRKHKTEPYRSPAMAGGLFAIEKDFFFELGLYDPGLQIWGGENFEISYKIWQCGGKLLFVPCSRVGHIYRLEGWQGNPPPLYVGSSPTLKNYVRVVEVWWDEYKDYFYASR-PESKALPYGDISELKKFREDHNCKSFKWFMEEIAYDITAHYPLPPRNVEWGEIRGLET--AYCIDSMGKTNGGFVELGPCHRMGGN-----QLFRINEANQLM--QYDQCLTKGPDGSKVMITHCNL-NEFKEWQYFKSLHRFTHITSGKCLDRSEVLHQVFISTCDSSKMTQKW 649          

Query:  262 MKRMNSTRRFNNSFEEEKVSLYRTINELKITKCKWLRHNKTLPSVSIIITFYDSDWEXXXXXXXXXXXXSPRRLIKEXXXXXXXXXXXXMRSKMNAYISKNFTNVRVVHKTKREXXXXXXXXXXXXXXXXVLVFMDSHCTVGVKWLPPLLEPIKENYKTVTCPFIDINDTDTSLY-SQDEGARGAFDWNFNYTRLP----RLHNNKTDPEDPFDNPIMQGRIFAITRKWFWELGGYDEGLEIWGGEQFELSFKIWMCGGRMVNVPCSRIRCIFKDIYSFDFIHDDIK-IRKNYKRIAEIWMDNWKKFIYQRHLEEYSSFDCGDISXXXXXXXXXNCKSFDWFMENVAYDILYLYPPITVSEKLNCSITLESDDSICVDSKYRKQGDRVGIDQCNQIGRSEKNKEQRFSFTSDFEIRPGQRNLCFDYRNSSETLMLSQCDLMNPNQKWEYNSTSHQITNIPSQKCI 1638
            MK M    +FN     E ++L R++ ++++  CK   +   LP+ S++I F++  W TL++T   ++ RSPR +I+EI+++DD ++ + ++  + +Y+ K    V V+   +R GLI+ARL GA +++G+V+ F+D+HC     WL PLL  IK + +TV CP ID+   DT  Y +  +   G F+W  N+   P     +   K D   P   P M G +F+I R +F E+G YD G++IWGGE  E+SF+IW CGG +  V CS +  +F+    + F     + I KN +R+AE+WMD +K F Y       +  D GDIS +  L++KL CK F W++EN+  D        ++ E  N       + + C+D+  RK+ ++VGI  C+ +G +     Q FS+T++ EIR    +LC D    +  + + +C  +  NQ WEY+     + ++ S +C+
Sbjct:   75 MKEMFKINQFN-LMASEMIALNRSLPDVRLEGCKTKVYPDNLPTTSVVIVFHNEAWSTLLRTVHSVINRSPRHMIEEIVLVDDASERDFLKRPLESYVKKLKVPVHVIRMEQRSGLIRARLKGAAVSRGQVITFLDAHCECTAGWLEPLLARIKHDRRTVVCPIIDVISDDTFEYMAGSDMTYGGFNWKLNFRWYPVPQREMDRRKGDRTLPVRTPTMAGGLFSIDRDYFQEIGTYDAGMDIWGGENLEISFRIWQCGGTLEIVTCSHVGHVFRKATPYTFPGGTGQIINKNNRRLAEVWMDEFKNFFYIIS-PGVTKVDYGDISSRLGLRRKLQCKPFSWYLENIYPDSQIPRHYFSLGEIRNV------ETNQCLDNMARKENEKVGIFNCHGMGGN-----QVFSYTANKEIR--TDDLCLDVSKLNGPVTMLKCHHLKGNQLWEYDPVKLTLQHVNSNQCL 524          

Query:  295 NSFEEEKVSLYRTINELKITKCKWLRHNKTLPSVSIIITFYDSDWEXXXXXXXXXXXXSPRRLIKEXXXXXXXXXXXXMRSKMNAYISKNFTN--VRVVHKTKREXXXXXXXXXXXXXXXXVLVFMDSHCTVGVKWLPPLLEPIKENYKTVTCPFIDINDTDT-SLYSQDEGARGAFDWNFNYTRLPRLHNNKTDPEDPFDNPIMQGRIFAITRKWFWELGGYDEGLEIWGGEQFELSFKIWMCGGRMVNVPCSRIRCIFKDIYS-FDFIHDDIKIRKNYKRIAEIWMDNWKKFIYQRHLEEYSSFDCGDISXXXXXXXXXNCKSFDWFMENVAYDILYLYPPITVSEKLNCSITLESDDSICVDSKYRKQGDRVGIDQCNQIGRSEKNKEQRFSFTSDFEIRPGQRNLCFDYRNSSE--TLMLSQCDLMNPNQKWEYNSTSHQITNIPSQKCI 1638
            N++  + +SL R+I +++  +CK + ++  LP+VS+I  F++    TL+++   ++ RSP  L+KEI+++DD ++   +R  +  ++ KN  +  V+++   KREGLI+ R LGA+ A G++L+F+D+H      WLPPLL+PI ++Y+TV CPF+D+ D +T  +  QDEGARG+FDW FNY RLP    ++ +P  PFD+P+M G  FAI+ KWFWELGGYDEGL+IWGGEQ+ELSFK+W C G+MV+ PCSR+  I++  Y+ F        + +NYKR+AE+WMD +K+ +Y +H     + D GD+   K +++KL CKSFDWFM+ +A+D    YP I         I   + + +C+D+++++Q  R G+ +C    + +   EQ    T   +IRP  R +CFD   S +   ++L  C  M  NQ ++Y     QI +  S +C+
Sbjct:  133 NAYISDMISLNRSIKDIRHKECKKMTYSAKLPTVSVIFPFHEEHNSTLLRSVYSVINRSPPELLKEIILVDDFSEKPALRQPLEDFLKKNKIDHIVKILRTKKREGLIRGRQLGAQEATGEILIFLDAHSECNYNWLPPLLDPIADDYRTVVCPFVDVIDCETYEIRPQDEGARGSFDWAFNYKRLPLTKKDRENPTKPFDSPVMAGGYFAISAKWFWELGGYDEGLDIWGGEQYELSFKVWQCHGKMVDAPCSRVAHIYRCKYAPFKNAGMGDFVSRNYKRVAEVWMDEYKETLY-KHRPGIGNADAGDLKLMKGIREKLQCKSFDWFMKEIAFDQDKYYPAIEPKASAEGEIRHVASN-LCIDTQFKEQNQRFGLRKCASEDK-DGGGEQDLRLTRWHDIRPKGRKICFDVSTSVDKAPIILFDCHSMKGNQLFKYRMPQKQIYHPVSGQCL 583          

Query:  295 NSFEEEKVSLYRTINELKITKCKWLRHNKTLPSVSIIITFYDSDWEXXXXXXXXXXXXSPRRLIKEXXXXXXXXXXXXMRSKMNAYISKNFTN--VRVVHKTKREXXXXXXXXXXXXXXXXVLVFMDSHCTVGVKWLPPLLEPIKENYKTVTCPFIDINDTDT-SLYSQDEGARGAFDWNFNYTRLPRLHNNKTDPEDPFDNPIMQGRIFAITRKWFWELGGYDEGLEIWGGEQFELSFKIWMCGGRMVNVPCSRIRCIFKDIYS-FDFIHDDIKIRKNYKRIAEIWMDNWKKFIYQRHLEEYSSFDCGDISXXXXXXXXXNCKSFDWFMENVAYDILYLYPPITVSEKLNCSITLESDDSICVDSKYRKQGDRVGIDQCNQIGRSEKNKEQRFSFTSDFEIRPGQRNLCFDYRNSSE--TLMLSQCDLMNPNQKWEYNSTSHQITNIPSQKCI 1638
            N++  + +SL R+I +++  +CK + ++  LP+VS+I  F++    TL+++   ++ RSP  L+KEI+++DD ++   +R  +  ++ KN  +  V+V+   KREGLI+ R LGA+ A G++L+F+D+H      WLPPLL+PI E+Y+TV CPF+D+ D +T  +  QDEGARG+FDW FNY RLP    ++  P  PF++P+M G  FAI+ KWFWELGGYDEGL+IWGGEQ+ELSFK+W C GRMV+ PCSR+  I++  Y+ F        + +NYKR+AE+WMD++K+ +Y +H     + D GD+   K +++KL CKSFDWFM+ +A+D    YP +         I      + C+D+++++Q  R G+ +C    + +   EQ    T   +IRP  R +CFD   S +   ++L  C  M  NQ ++Y     QI +  S +C+
Sbjct:  188 NAYISDMISLNRSIKDIRHKECKNMMYSAKLPTVSVIFPFHEEHNSTLLRSVYSVINRSPPELLKEIILVDDFSEKPALRQPLEDFLKKNKIDHIVKVLRTKKREGLIRGRQLGAQDATGEILIFLDAHSEANYNWLPPLLDPIAEDYRTVVCPFVDVIDCETYEVRPQDEGARGSFDWAFNYKRLPLTKKDRESPTKPFNSPVMAGGYFAISAKWFWELGGYDEGLDIWGGEQYELSFKVWQCHGRMVDAPCSRVAHIYRCKYAPFKNAGMGDFVSRNYKRVAEVWMDDYKETLY-KHRPGVGNADAGDLKLMKGIREKLQCKSFDWFMKEIAFDQDKYYPAVEPKASAEGEIR-NVGTNFCIDTQFKEQNQRFGLRKCTSDDK-DGGGEQDLRLTRWHDIRPKGRKICFDCSTSVDKAPVILFDCHSMKGNQLFKYRVAQKQIYHPISGQCL 638          

Query:  265 KRMNSTRRFN--NSFEEEKVSLYRTINELKITKCKWLRHNKTLPSVSIIITFYDSDWEXXXXXXXXXXXXSPRRLIKEXXXXXXXXXXXXMRSKMNAYISKNFTNVRVVHKTKREXXXXXXXXXXXXXXXXVLVFMDSHCTVGVKWLPPLLEPIKENYKTVTCPFIDINDTDTSLYSQDEG--ARGAFDWNFNYTRLP-RLHNNKTDPEDPFDNPIMQGRIFAITRKWFWELGGYDEGLEIWGGEQFELSFKIWMCGGRMVNVPCSRIRCIFKDIYSFDFIHDDIKIRKNYKRIAEIWMDNWKKFIYQRHLEEYSSFDCGDISXXXXXXXXXNCKSFDWFMENVAYDILYLYPPITVSEKLNCSITLESDDSICVDSKYRKQGDRVGIDQCNQIGRSEK--NKEQRFSFTSDFEIRPGQ----RNLCFDYRNSSETLMLSQCDLMNPNQKWEY 1590
            +R++   R N  N +  +K+SL R++ +++   C   R+ +TLP+ SIII F++  W +L++T   +L RSP  L+ EI+++DD +D   ++  +  Y++  F +VR++   KREGLI+ R+LGA +A G V+ F+DSHC   V WLPPLL+ I  N KT+ CP ID+ D D   Y    G   RGAFDW   Y R+P      K DP DPF++P+M G +FA+ RKWFWELGGYD GLEIWGGEQ+E+SFK+WMCGGRM ++PCSR+  I++    +  +   + + +N KR+AE+WMD + ++IYQR   EY     GD++ QKKL+  LNCKSF WFM  +A+D+   YPP+         I       +C D+K+   G  + ++ C + GR E   N  Q F+FT   +IRPG     +  CFD  + +  + L  C  M  NQ W+Y
Sbjct:  102 ERVDQAYRENGFNIYVSDKISLNRSLPDIRHPNCNSKRYLETLPNTSIIIPFHNEGWSSLLRTVHSVLNRSPPELVAEIVLVDDFSDREHLKKPLEDYMAL-FPSVRILRTKKREGLIRTRMLGASVATGDVITFLDSHCEANVNWLPPLLDRIARNRKTIVCPMIDVIDHDDFRYETQAGDAMRGAFDWEMYYKRIPIPPELQKADPSDPFESPVMAGGLFAVDRKWFWELGGYDPGLEIWGGEQYEISFKVWMCGGRMEDIPCSRVGHIYRKYVPYK-VPAGVSLARNLKRVAEVWMDEYAEYIYQRR-PEYRHLSAGDVAVQKKLRSSLNCKSFKWFMTKIAWDLPKFYPPVEPPAAAWGEIR-NVGTGLCADTKHGALGSPLRLEGCVR-GRGEAAWNNMQVFTFTWREDIRPGDPQHTKKFCFDAISHTSPVTLYDCHSMKGNQLWKY 549          

Query:  220 DQENIRNLSNINLMMKRMNSTRRFNNSFEEEKVSLYRTINELKITKCKWLRHNKTLPSVSIIITFYDSDWEXXXXXXXXXXXXSPRRLIKEXXXXXXXXXXXXMRSKMNAYISKNFTNVRVVHKTKREXXXXXXXXXXXXXXXXVLVFMDSHCTVGVKWLPPLLEPIKENYKTVTCPFIDIND-TDTSLYSQDEGARGAFDWNFNYTRLPRLHNNKTDPEDPFDNPIMQGRIFAITRKWFWELGGYDEGLEIWGGEQFELSFKIWMCGGRMVNVPCSRIRCIFKDIYSF-------DFIHDDIKIRKNYKRIAEIWMDNWKKFIYQRHLEEYSSFDCGDISXXXXXXXXXNCKSFDWFMENVAYDILYLYPPITVSEKLNCSITLESDDSICVDSKYRKQGDRVGIDQC-NQIGRSEKNKEQRFSFTSDFEIRPGQRNLCFDYR--NSSETLMLSQCDLMNPNQKWEYNSTSHQITN 1617
            D E+ R+L       KRM+    FN +   + +S+ R++ +++   C+   +   LP+VS+II FY+     LM++   L+ RSP  L+KEI+++DD++D   +  ++  YI+++F  VRVV   +R GLI AR  GA+ A  +VL+F+DSH      WLPPLLEPI  N +T  CPFID+ D T+    +QDEGARGAFDW F Y RLP L  +   P DPF +PIM G +FAI+R++FWELGGYDEGL+IWGGEQ+ELSFKIWMCGG M + PCSRI  I++   +        D++H      KNYKR+AE+WMD +K ++Y      Y S D GD+++QK ++ KLNCKSF WFME VA+D++  YPP+        ++    + ++C+D+  RK+ +++G+  C + I   ++ +    S+  D  +R  ++  C D +  +++  + L  C     NQ W Y+    Q+ +
Sbjct:  153 DDESQRDLE------KRMSLENGFN-ALLSDSISVNRSVPDIRHPLCRKKEYVAKLPTVSVIIIFYNEYLSVLMRSVHSLINRSPPELMKEIILVDDHSDREYLGKELETYIAEHFKWVRVVRLPRRTGLIGARAAGARNATAEVLIFLDSHVEANYNWLPPLLEPIALNKRTAVCPFIDVIDHTNFHYRAQDEGARGAFDWEFFYKRLPLLPEDLKHPADPFKSPIMAGGLFAISREFFWELGGYDEGLDIWGGEQYELSFKIWMCGGEMYDAPCSRIGHIYRGPRNHQPSPRKGDYLH------KNYKRVAEVWMDEYKNYLYSHGDGLYESVDPGDLTEQKAIRTKLNCKSFKWFMEEVAFDLMKTYPPVDPPSYAMGALQNVGNQNLCLDTLGRKKHNKMGMYACADNIKTPQRTQFWELSWKRDLRLR--RKKECLDVQIWDANAPVWLWDCHSQGGNQYWYYDYRHKQLKH 614          

Query:  265 KRMNSTRRFN--NSFEEEKVSLYRTINELKITKCKWLRHNKTLPSVSIIITFYDSDWEXXXXXXXXXXXXSPRRLIKEXXXXXXXXXXXXMRSKMNAYISKNFTNVRVVHKTKREXXXXXXXXXXXXXXXXVLVFMDSHCTVGVKWLPPLLEPIKENYKTVTCPFIDINDTDTSLYSQDEG--ARGAFDWNFNYTRLP-RLHNNKTDPEDPFDNPIMQGRIFAITRKWFWELGGYDEGLEIWGGEQFELSFKIWMCGGRMVNVPCSRIRCIFKDIYSFDFIHDDIKIRKNYKRIAEIWMDNWKKFIYQRHLEEYSSFDCGDISXXXXXXXXXNCKSFDWFMENVAYDILYLYPPITVSEKLNCSITLESDDSICVDSKYRKQGDRVGIDQCNQIGRSEK--NKEQRFSFTSDFEIRPGQ----RNLCFDYRNSSETLMLSQCDLMNPNQKWEY 1590
            +R++   R N  N +  +K+SL R++ +++   C    + +TLP+ SIII F++  W +L++T   +L RSP  L+ EI+++DD +D   ++  +  Y++  F +VR++   KREGLI+ R+LGA  A G V+ F+DSHC   V WLPPLL+ I  N KT+ CP ID+ D D   Y    G   RGAFDW   Y R+P      K DP DPF++P+M G +FA+ RKWFWELGGYD GLEIWGGEQ+E+SFK+WMCGGRM ++PCSR+  I++    +  +   + + +N KR+AE+WMD + ++IYQR   EY     GD+  QKKL+  LNCKSF WFM  +A+D+   YPP+         I       +C D+K+   G  + ++ C + GR E   N  Q F+FT   +IRPG     +  CFD  + +  + L  C  M  NQ W+Y
Sbjct:  102 ERVDQAYRENGFNIYVSDKISLNRSLPDIRHPNCNSKLYLETLPNTSIIIPFHNEGWSSLLRTVHSVLNRSPPELVAEIVLVDDFSDREHLKKPLEDYMAL-FPSVRILRTKKREGLIRTRMLGASAATGDVITFLDSHCEANVNWLPPLLDRIARNRKTIVCPMIDVIDHDDFRYETQAGDAMRGAFDWEMYYKRIPIPPELQKADPSDPFESPVMAGGLFAVDRKWFWELGGYDPGLEIWGGEQYEISFKVWMCGGRMEDIPCSRVGHIYRKYVPYK-VPAGVSLARNLKRVAEVWMDEYAEYIYQRR-PEYRHLSAGDVVAQKKLRGSLNCKSFKWFMTKIAWDLPKFYPPVEPPAAAWGEIR-NVGTGLCTDTKHGTLGSPLRLETCIR-GRGEAAWNSMQVFTFTWREDIRPGDPQHTKKFCFDAVSHTSPVTLYDCHSMKGNQLWKY 549          

Query:  295 NSFEEEKVSLYRTINELKITKCKWLRHNKTLPSVSIIITFYDSDWEXXXXXXXXXXXXSPRRLIKEXXXXXXXXXXXXMRSKMNAYISKNFTNVRVVHKTKREXXXXXXXXXXXXXXXXVLVFMDSHCTVGVKWLPPLLEPIKENYKTVTCPFIDINDTDTSLY-SQDEGARGAFDWNFNYTRLPRLHNNKTDPEDPFDNPIMQGRIFAITRKWFWELGGYDEGLEIWGGEQFELSFKIWMCGGRMVNVPCSRIRCIFKDIYSFDFIHDDIKIRKNYKRIAEIWMDNWKKFIYQRHLEEYSSFDCGDISXXXXXXXXXNCKSFDWFMENVAYDILYLYPPITVSEKLNCSITLESDDSICVDSKYRKQGDRVGIDQCNQIGRSEKNKEQRFSFTSDFEIRPGQRNLCFDYRNSS--ETLMLSQCDLMNPNQKWEYNSTSHQITNIPSQKCI 1638
            N+   +K+SL+R++ +++ + C+  R+ + LP+ SIII F++  W TL++T    + R+PR L+KE++++DD +  + +   +  Y+S +FTNVRV+   KREGLI+ R+ GA+ A G VL+F+DSHC   + WLPPLL PI  NYKTV CPFID+ D +T  Y +QDEGARGAFDW F Y RLP L  +   P  PFD+P+M G +FAI+ KWFWELGGYD GL+IWGGEQ+ELSFKIW CGGRMV+  CSRI  +++    F        I +NY+R+AE+WMD + ++IY R    Y S   GD++ Q++++++L+CK F WFM NVA+D+   YPP+      +  I   +D S+C+D++++      G+ +C + G    + EQ F FT   +I P  R  CFD    +    ++L QC     NQ W+ N  + Q+ ++ S+ C+
Sbjct:  116 NALVSDKMSLFRSLADIRHSACQGERYRRGLPTASIIIPFHEEHWSTLLRTVVSCIHRAPRHLVKEVILVDDFSKKSFLGDPLEKYVSAHFTNVRVLRNAKREGLIRTRIFGARNATGDVLIFLDSHCECNINWLPPLLHPIANNYKTVVCPFIDVIDFNTFAYRAQDEGARGAFDWEFYYKRLPLLPEDLKHPSKPFDSPVMAGGLFAISTKWFWELGGYDPGLDIWGGEQYELSFKIWQCGGRMVDTGCSRIGHVYRKYAPFPNPGVGDFIGRNYRRVAEVWMDEYAEYIYNRR-PHYKSIPAGDLTSQREIRERLHCKPFKWFMTNVAFDLPLRYPPVEPPSAASGEIRSAADASLCIDTRFKGGMQSFGLAKCIK-GGGGLSGEQNFIFTFRKDIHPADRAFCFDVSQHAVKAPVILYQCHYQKGNQHWKINPNTGQLYHVASRLCL 564          

Query:  295 NSFEEEKVSLYRTINELKITKCKWLRHNKTLPSVSIIITFYDSDWEXXXXXXXXXXXXSPRRLIKEXXXXXXXXXXXXMRSKMNAYISKNFTNVRVVHKTKREXXXXXXXXXXXXXXXXVLVFMDSHCTVGVKWLPPLLEPIKENYKTVTCPFIDINDTDTSLY-SQDEGARGAFDWNFNYTRLPRLHNNKTDPEDPFDNPIMQGRIFAITRKWFWELGGYDEGLEIWGGEQFELSFKIWMCGGRMVNVPCSRIRCIFKDIYSFDFIHDDIKIRKNYKRIAEIWMDNWKKFIYQRHLEEYSSFDCGDISXXXXXXXXXNCKSFDWFMENVAYDILYLYPPITVSEKLNCSITLESDDSICVDSKYRKQGDRVGIDQCNQIGRSEKNKEQRFSFTSDFEIRPGQRNLCFDYRNSS--ETLMLSQCDLMNPNQKWEYNSTSHQITNIPSQKCI 1638
            N+   +K+SL+R++ +++ + C+  R+ + LP+ SIII F++  W TL++T    + R+PR L+KE++++DD +  + +   +  Y+S +FTNVRV+   KREGLI+ R+ GA+ A G VL+F+DSHC   + WLPPLL PI  NYKTV CPFID+ D +T  Y +QDEGARGAFDW F Y RLP L  +   P  PFD+P+M G +FAI+ KWFWELGGYD GL+IWGGEQ+ELSFKIW CGGRMV+  CSRI  +++    F        I +NY+R+AE+WMD + ++IY R    Y S   GD++ Q++++++L+CK F WFM NVA+D+   YPP+      +  I   +D S+C+D++++      G+ +C + G    + EQ F FT   +I P  R  CFD    +    ++L QC     NQ W+ N  + Q+ ++ S+ C+
Sbjct:  116 NALVSDKMSLFRSLADIRHSACQGERYRRGLPTASIIIPFHEEHWSTLLRTVVSCIHRAPRHLVKEVILVDDFSKKSFLGDPLEKYVSAHFTNVRVLRNAKREGLIRTRIFGARNATGDVLIFLDSHCECNINWLPPLLHPIANNYKTVVCPFIDVIDFNTFAYRAQDEGARGAFDWEFYYKRLPLLPEDLKHPSKPFDSPVMAGGLFAISTKWFWELGGYDPGLDIWGGEQYELSFKIWQCGGRMVDTGCSRIGHVYRKYAPFPNPGVGDFIGRNYRRVAEVWMDEYAEYIYNRR-PHYKSIPAGDLTSQREIRERLHCKPFKWFMTNVAFDLPLRYPPVEPPSAASGEIRSAADASLCIDTRFKGGMQSFGLAKCIK-GGGGLSGEQNFIFTFRKDIHPADRAFCFDVSQHAVKAPVILYQCHYQKGNQHWKINPNTGQLYHVASRLCL 564          

Query:  295 NSFEEEKVSLYRTINELKITKCKWLRHNKTLPSVSIIITFYDSDWEXXXXXXXXXXXXSPRRLIKEXXXXXXXXXXXXMRSKMNAYISKNFTNVRVVHKTKREXXXXXXXXXXXXXXXXVLVFMDSHCTVGVKWLPPLLEPIKENYKTVTCPFIDINDTDTSLY-SQDEGARGAFDWNFNYTRLPRLHNNKTDPEDPFDNPIMQGRIFAITRKWFWELGGYDEGLEIWGGEQFELSFKIWMCGGRMVNVPCSRIRCIFKDIYSFDFIHDDIKIRKNYKRIAEIWMDNWKKFIYQRHLEEYSSFDCGDISXXXXXXXXXNCKSFDWFMENVAYDILYLYPPITVSEKLNCSITLESDDSICVDSKYRKQGDRVGIDQCNQIGRSEKNKEQRFSFTSDFEIRPGQRNLCFDYRNS--SETLMLSQCDLMNPNQKWEYNSTSHQITNIPSQKCIXXXXXXXXXXXXXXXXXXTMQKWIIQGCND 1728
            N+F  +K+SL R++ +++   CK  ++   LP+ S+I+ F++  W TL++    +L R+P+ ++ EI++ DD ++    +  ++ Y+ ++F NVRVV   +REGLI+ R++GAK A G+VL+F+DSH    + WLPPLLEPI E+YKTV CPFID+ D +T  Y +QDEGARGAFDW F Y RLP L  +   P +PF++P+M G +FAI+ KWFWELGGYD GL+IWGGEQ+ELSFK+W CGG+MV+ PCSRI  I++    F        + +NY+R+AE+WMD + +++Y  H   Y + D GDIS QK ++ KLNCK F WFME VA+D+   YPP+         I    D ++C+D++Y+ Q +R  ++ C + G+     EQ F F+   +IRPG+R++CFD   S     ++L  C  M  NQ+++YN  + QI ++ S +C+  ++ S  L  N C  +   Q+W IQ  N+
Sbjct:  115 NAFASDKISLQRSLKDIRHADCKSKKYLNHLPNASVIVPFHNEHWTTLLRLCYSVLNRAPKGMVHEIILADDFSNKEHCKKPLDDYLKEHFDNVRVVRAKQREGLIRTRIMGAKAATGQVLIFLDSHVEANINWLPPLLEPIAEDYKTVVCPFIDVIDFETFAYRAQDEGARGAFDWEFFYKRLPLLPEDLKHPAEPFNSPVMAGGLFAISTKWFWELGGYDPGLDIWGGEQYELSFKLWQCGGKMVDAPCSRIGHIYRKFAPFPNPGVGDFVGRNYRRVAEVWMDEYAEYLYN-HRPHYRNIDTGDISAQKAIRTKLNCKPFKWFMEKVAFDLPKFYPPVEPPPFAKGEIR-NVDANLCIDTRYKGQNERFQLEPCLKDGKG--GGEQEFQFSWHKDIRPGKRSVCFDVSQSIKKSPIILFNCHGMGGNQRFKYNLDTSQIYHVISNQCLDCDAGSHELFTNPCDKNLKSQQWKIQTVNE 591          

Query:  190 EHKLENHGLSDQENIRNLSNINLMMKRMNSTRRFNNSFEEEKVSLYRTINELKITKCKWLRHNKTLPSVSIIITFYDSDWEXXXXXXXXXXXXSPRRLIKEXXXXXXXXXXXXMRSKMNAYISKNFTNVRVVHKTKREXXXXXXXXXXXXXXXXVLVFMDSHCTVGVKWLPPLLEPIKENYKTVTCPFIDINDTDTSLY-SQDEGARGAFDWNFNYTRLPRLHNNKTDPEDPFDNPIMQGRIFAITRKWFWELGGYDEGLEIWGGEQFELSFKIWMCGGRMVNVPCSRIRCIFKDIYSFDFIHDDIKIRKNYKRIAEIWMDNWKKFIYQRHLEEYSSFDCGDISXXXXXXXXXNCKSFDWFMENVAYDILYLYPPITVSEKLNCSITLESDDSICVDSKYRKQGDRVGIDQCNQIGRSEKNKEQRFSFTSDFEIRPGQRNLCFDYRNSSE--TLMLSQCDLMNPNQKWEYNSTSHQITNIPSQKCI 1638
            E +L+  G  +Q +   LS  + + K +       N+   +K+SL R+I +++   CK  ++ K LP+ S I+ F++    TL+++   ++ R+P+ L+KEI++ DD+++ ++ +  ++ Y+ ++FTNV++V   KREGLI+ RLLGA+ A G+VL+F+DSH    + +LPPLLEPI +NY+TV CPFID+ D +   Y +QDEGARGAFDW F Y RLP L  +K  P +PF NP+M G +FAI+++WFWELGGYD GL+IWGGEQ+ELSFKIW CGG MV+ PCSRI  I++    F        + +NYKR+AE+WMD + ++IY  H   Y S D GD++ QK ++QKLNCK F WFME VA+D++  YPP+        +I   + D +C+D+K++ QGD   ++ C     + + KEQ+F  T   +IRP  R LCFD   S    +++L  C  M  NQ+++YN  ++QI +  S  C+
Sbjct:   76 EEELKRQGPGEQGSAFKLSPEDELQKNLLYRSNGFNALVSDKISLQRSIKDIRHPHCKSKQYVKFLPTASFILPFHNEHLSTLLRSVYSIINRAPKELVKEIILTDDHSNKDECKKPLDDYVKEHFTNVKIVRAEKREGLIRTRLLGARHATGEVLIFLDSHIECNINFLPPLLEPIAQNYRTVVCPFIDVIDYENFEYRAQDEGARGAFDWEFYYKRLPLLEEDKKKPSEPFANPVMAGGLFAISKEWFWELGGYDPGLDIWGGEQYELSFKIWQCGGTMVDAPCSRIGHIYRKFAPFSNPGVGDFLGRNYKRVAEVWMDEYAEYIYS-HRPHYRSLDAGDLTSQKAIRQKLNCKPFKWFMEEVAFDLVKFYPPVEPPAMAKGTIRNMAID-LCIDTKFKSQGDTFSVETCAD--STARAKEQQFELTWHKDIRPQGRLLCFDVSESKPRTSVILFSCHGMQGNQRFKYNVDTNQIFHPISGLCM 557          

Query:  295 NSFEEEKVSLYRTINELKITKCKWLRHNKTLPSVSIIITFYDSDWEXXXXXXXXXXXXSPRRLIKEXXXXXXXXXXXXMRSKMNAYISKNFTNVRVVHKTKREXXXXXXXXXXXXXXXXVLVFMDSHCTVGVKWLPPLLEPIKENYKTVTCPFIDINDTDTSLY-SQDEGARGAFDWNFNYTRLPRLHNNKTDPEDPFDNPIMQGRIFAITRKWFWELGGYDEGLEIWGGEQFELSFKIWMCGGRMVNVPCSRIRCIFKDIYSFDFIHDDIKIRKNYKRIAEIWMDNWKKFIYQRHLEEYSSFDCGDISXXXXXXXXXNCKSFDWFMENVAYDILYLYPPITVSEKLNCSITLESDDSICVDSKYRKQGDRVGIDQCNQIGRSEKNKEQRFSFTSDFEIRPGQRNLCFDYRNS--SETLMLSQCDLMNPNQKWEYNSTSHQITNIPSQKCI 1638
            N++  +K+SL+R++ +++ + CK  ++   L + S+I+ F++  W TL++T   +L RSP+ LI E++++DD +     +  ++ Y+ ++FTNV+VV   KREGLI+ RLLGA+ A G+VL+F+DSHC   + WLPPLLEPI E+YKTV CPFID+ D +   Y +QDEGARGAFDW F Y RLP L  +   P +PF +P+M G +FAI+ KWFWE+GGYD GL+IWGGEQ+ELSFK+W CGG MV+ PCSRI  I++    F        + +NY+R+AE+WMD + +++Y+R    Y + D GD+S+QK ++ KL+CK F WFME VA+D+   YPP+      +  +  ++ + +C+D++Y+ Q +R  +  C + G+     EQ+F FT   +IRPG+R +CFD   S     ++L  C  M  NQ+++YN  + QI ++ S +C+
Sbjct:   40 NAYASDKISLHRSLKDIRHSDCKKKKYLNHLMNASVIVPFHNEHWSTLLRTAWSVLNRSPKHLIHEVILVDDYSSKEHCKQPLDDYVKEHFTNVKVVRAKKREGLIRTRLLGARAATGQVLIFLDSHCEANINWLPPLLEPIAEDYKTVVCPFIDVIDFENFAYRAQDEGARGAFDWEFFYKRLPLLEEDLKHPAEPFKSPVMAGGLFAISAKWFWEMGGYDPGLDIWGGEQYELSFKLWQCGGMMVDAPCSRIGHIYRKFAPFPNPGVGDFVGRNYRRVAEVWMDEYAEYLYKRR-PHYRNIDPGDVSEQKAIRDKLHCKPFKWFMEEVAFDLPKFYPPVEPPPFASGEVRNKAAN-MCLDTRYKGQNERFDLQPCLKDGKG--GGEQQFEFTWHKDIRPGKRTVCFDVSQSIKKAPVILFNCHGMGGNQRFKYNIDTQQIYHVISNQCL 486          

Query:  268 RMNSTRRFN--NSFEEEKVSLYRTINELKITKCKWLRHNKTLPSVSIIITFYDSDWEXXXXXXXXXXXXSPRRLIKEXXXXXXXXXXXXMRSKMNAYISKNFTNVRVVHKTKREXXXXXXXXXXXXXXXXVLVFMDSHCTVGVKWLPPLLEPIKENYKTVTCPFIDINDTDTSLYSQDEG--ARGAFDWNFNYTRLP-RLHNNKTDPEDPFDNPIMQGRIFAITRKWFWELGGYDEGLEIWGGEQFELSFKIWMCGGRMVNVPCSRIRCIFKDIYSFDFIHDDIKIRKNYKRIAEIWMDNWKKFIYQRHLEEYSSFDCGDISXXXXXXXXXNCKSFDWFMENVAYDILYLYPPITVSEKLNCSITLESDDSICVDSKYRKQGDRVGIDQCNQIGRSEK--NKEQRFSFTSDFEIRPGQ----RNLCFDYRNSSETLMLSQCDLMNPNQKWEY---NSTSHQITNIPSQKCIXXXXXXXXXXXXXXXXXXTMQKWIIQGCN 1725
            R++   R N  N +   ++SL R++ +++   CK   +++ LP+ SIII F++  W +L++T   +L RSP  LI EI+++DD +D   +++ +  Y+ +    VR++   KREGLI+ RLLGA  AKG+V+ F+DSHC   V WLPPLL+ I +N K + CP ID+ D D   Y    G   RGAFDW   Y R+P      K DP +PF++P+M G +FA+ RKWFWELGGYD GLEIWGGEQ+E+SFK+WMCGGRM ++PCSR+  I++    +  +   + + +N KR+AE+WMD + ++IYQR   EY     GD++ QK+L+ +LNCK+F WFM +VA+D+   YPP+         +       +C++SK+   G  + ++ C + GR E   +  Q F+F    +IR G     + +CFD  + +  + L  C  M  NQ W Y    +  H I+N     CI  N     + +N+C  S   Q+W+ +  N
Sbjct:    6 RVDQAYRENGFNIYVSNRISLNRSLPDIRHPNCKLKLYSERLPNTSIIIPFHNEGWSSLLRTVHSILNRSPPELIAEIILVDDFSDREHLKASLEDYMVR-MPKVRILRTKKREGLIRTRLLGAAAAKGEVITFLDSHCEANVNWLPPLLDRIAQNRKAIVCPMIDVIDHDNFGYETQAGDAMRGAFDWEMYYKRIPIPAELQKDDPSEPFESPVMAGGLFAVDRKWFWELGGYDTGLEIWGGEQYEISFKVWMCGGRMEDIPCSRVGHIYRKYVPYK-VPGGVSLARNLKRVAEVWMDEYAEYIYQRR-PEYRHLSAGDVTTQKELRARLNCKNFKWFMTDVAWDLPKHYPPVEPPAAAWGELR-NVGSGLCMESKHFSSGTPLRMEVCVK-GRGETAWSHGQVFTFGWREDIRVGDPLHTKKVCFDAISHNSPVTLYDCHGMKGNQLWRYRKDKTLYHPISN----SCIDHNPNEKRVFMNSCDASIATQQWVFERTN 496          

Query:  295 NSFEEEKVSLYRTINELKITKCKWLRHNKTLPSVSIIITFYDSDWEXXXXXXXXXXXXSPRRLIKEXXXXXXXXXXXXMRSKMNAYISKNFTNVRVVHKTKREXXXXXXXXXXXXXXXXVLVFMDSHCTVGVKWLPPLLEPIKENYKTVTCPFIDINDTDTSLYSQDEG--ARGAFDWNFNYTRLP-RLHNNKTDPEDPFDNPIMQGRIFAITRKWFWELGGYDEGLEIWGGEQFELSFKIWMCGGRMVNVPCSRIRCIFKDIYSFDFIHDDIKIRKNYKRIAEIWMDNWKKFIYQRHLEEYSSFDCGDISXXXXXXXXXNCKSFDWFMENVAYDILYLYPPITVSEKLNCSITLESDDSICVDSKYRKQGDRVGIDQCNQIGRSEK-NKEQRFSFTSDFEIRPGQ----RNLCFDYRNSSETLMLSQCDLMNPNQKWEYNSTSHQITNIPSQKCIXXXXXXXXXXXXXXXXXXTMQKWIIQGCN 1725
            N +    ++L R++ +++   CK   + + LP+ SIII F++  W +L++T   ++ R+P  LI EI+++DD +D + + +++  Y+S+ F  VR+V   KREGLI+ RLLGA +AKG+VL F+DSHC   + WLPPLL+ I +N +T+ CP ID+ D +   Y    G   RGAFDW   Y R+P  L    +DP +P+++P+M G +FA+ R+WFWELGGYD GLEIWGGEQ+E+SFK+WMCGG M +VPCSR+  I++    +  +     + +N KR+AE WMD + ++IYQR   EY     GD++ QK+L++ L CK F W+M  VA+D+   YPP+         I   +   +CVDSK+   G  + +D C + G       EQ F+F    +IRPG     R  CFD  + S  + L  C  M  NQ W Y      + ++ S  C+  +     + +N C+  S  Q+W+ Q  N
Sbjct:  108 NIYVSNNIALDRSLPDIRHPNCKQKLYLENLPNTSIIIPFHNEGWSSLLRTIHSIVNRTPDHLIAEIILVDDYSDRDHLGARLEDYMSR-FPKVRIVRTKKREGLIRTRLLGASVAKGEVLTFLDSHCETNINWLPPLLDQIAQNPRTIVCPMIDVIDHNHFGYEAQAGDAMRGAFDWEMYYKRIPIPLELQGSDPSNPYESPVMAGGLFAVRRQWFWELGGYDTGLEIWGGEQYEISFKVWMCGGSMYDVPCSRVGHIYRKYVPYK-VPSGTSLARNLKRVAETWMDEFAEYIYQRR-PEYRHLSTGDLTAQKELRKHLKCKDFKWYMNTVAWDLPKYYPPVEPLPAAWGEIR-NAASGLCVDSKHGSTGTELRLDTCLKEGAERTWAHEQIFTFGWREDIRPGDPLHTRKFCFDAISQSSPVTLYDCHGMRGNQHWSYRKDK-SLYHLVSSGCMDCSPADKRIFMNKCNPQSETQQWLFQRVN 587          

Query:  262 MKRMNSTRRFNNSFEEEKVSLYRTINELKITKCKWLRHNKTLPSVSIIITFYDSDWEXXXXXXXXXXXXSPRRLIKEXXXXXXXXXXXXMRSKMNAYISKNFTNVRVVHKTKREXXXXXXXXXXXXXXXXVLVFMDSHCTVGVKWLPPLLEPIKENYKTVTCPFIDINDTDTSLY-SQDEGARGAFDWNFNYTRLP----RLHNNKTDPEDPFDNPIMQGRIFAITRKWFWELGGYDEGLEIWGGEQFELSFKIWMCGGRMVNVPCSRIRCIFKDIYSFDFIHDDIK-IRKNYKRIAEIWMDNWKKFIYQRHLEEYSSFDCGDISXXXXXXXXXNCKSFDWFMENVAYDILYLYPPITVSEKLNCSITLESDDSICVDSKYRKQGDRVGIDQCNQIGRSEKNKEQRFSFTSDFEIRPGQRNLCFDYRNSSETLMLSQCDLMNPNQKWEYNSTSHQITNIPSQKCI 1638
            MK M    +FN     E ++L R++ ++++  CK   +   LP  S++I F++  W TL++T   ++ RSPR L++E++++DD ++ + ++ K+  Y+ K    VR+V   +R GLI+ARL GA L+ G+V+ F+D+HC   + WL PLL  IK++ KTV CP ID+   DT  Y +  +   G F+W  N+   P     +   K D   P   P M G +F+I R +F E+G YD G++IWGGE  E+SF+IW CGG +  V CS +  +F+    + F     + I KN +R+AE+WMD +K F Y       +  D GDI+ +  L+QKL CK F W++ENV  D        ++ E  N       + + C+D+  RK+ ++VGI  C+ +G +     Q FS+T++ EIR    +LC D    +  +M+ +C  +  NQ W+Y+     + ++ S +C+
Sbjct:   73 MKEMFKINQFN-LMASEMIALNRSLPDVRLEGCKNKVYPDDLPRTSVVIVFHNEAWTTLLRTVHSVINRSPRHLLEEVVLVDDASERDFLKRKLEQYVRKLEVPVRIVRMEQRSGLIRARLKGASLSTGQVITFLDAHCECTMGWLEPLLSRIKQDKKTVVCPIIDVISDDTFEYMAGSDMTYGGFNWKLNFRWYPVPQREMDRRKGDRTLPVRTPTMAGGLFSIDRDYFQEIGTYDAGMDIWGGENLEISFRIWQCGGTLEIVTCSHVGHVFRKATPYTFPGGTGQIINKNNRRLAEVWMDEFKNFFYIIS-PGVTKVDYGDIATRASLRQKLQCKPFSWYLENVYPDSQIPRHYYSLGEIRNV------ETNQCLDNMARKENEKVGIFNCHGMGGN-----QVFSYTANKEIR--TDDLCLDVSKLNGPVMMLKCHHLKGNQLWDYDPLKLSLVHVNSNQCL 522          

Query:  220 DQENIRNLSNINLMMKRMNSTRRFNNSFEEEKVSLYRTINELKITKCKWLRHNKTLPSVSIIITFYDSDWEXXXXXXXXXXXXSPRRLIKEXXXXXXXXXXXXMRSKMNAYISKNFTNVRVVHKTKREXXXXXXXXXXXXXXXXVLVFMDSHCTVGVKWLPPLLEPIKENYKTVTCPFIDINDTDTSLY-SQDEGARGAFDWNFNYTRLP----RLHNNKTDPEDPFDNPIMQGRIFAITRKWFWELGGYDEGLEIWGGEQFELSFKIWMCGGRMVNVPCSRIRCIFKDIYSFDFIHDDIK-IRKNYKRIAEIWMDNWKKFIYQRHLEEYSSFDCGDISXXXXXXXXXNCKSFDWFMENVAYDILYLYPPITVSEKLNCSITLESDDSICVDSKYRKQGDRVGIDQCNQIGRSEKNKEQRFSFTSDFEIRPGQRNLCFDYRNSSETLMLSQCDLMNPNQKWEYNSTSHQITNIPSQKCI 1638
            DQE ++ L  IN             N    + ++L R++ ++++  CK   +   LP+ SI+I F++  W TL++T   ++ RSPR L+ EIL++DD ++ + ++ K+  Y+      VR++   +R GLI+ARL GA   +G+V+ F+D+HC   V WL PLL  IKE+ K V CP ID+   +T  Y +  +   G F+W  N+   P     +   K D   P   P M G +F+I R +F E+G YD G++IWGGE  E+SF+IW CGG +  V CS +  +F+    + F     + I KN +R+AE+WMD +K F Y          D GD+S +K L++ L CK F W++EN+  D        ++ E  N       + + CVD+  RK+ ++VG   C+ +G       Q FS+T+D EIR    +LC D    +  +++ +C  M  NQ +EY++      +I +Q C+
Sbjct:   70 DQEKMKELFKINQF-----------NLMASDMIALNRSLPDVRLDGCKTKVYPDDLPNTSIVIVFHNEAWSTLLRTVHSVINRSPRHLLVEILLVDDASERDFLKKKLEDYVKTLEVPVRILRMEQRSGLIRARLRGAAATRGQVITFLDAHCECTVGWLEPLLSRIKEDRKAVVCPIIDVISDETFEYMAGSDMTYGGFNWKLNFRWYPVPQREMDRRKGDRTLPVRTPTMAGGLFSIDRSYFEEIGTYDPGMDIWGGENLEMSFRIWQCGGSLEIVTCSHVGHVFRKATPYSFPGGTGQVINKNNRRLAEVWMDEFKDFFYIIS-PGVVRVDYGDVSARKALREALQCKPFSWYLENIYPDSQIPRRYFSLGEIRNV------ETNQCVDNMGRKENEKVGFFNCHGMG-----GNQVFSYTADKEIR--TDDLCLDVSRLNGPVVMLKCHHMKGNQMFEYDAEKGTFMHIITQSCL 523          

Query:  220 DQENIRNLSNINLMMKRMNSTRRFNNSFEEEKVSLYRTINELKITKCKWLRHNKTLPSVSIIITFYDSDWEXXXXXXXXXXXXSPRRLIKEXXXXXXXXXXXXMRSKMNAYISKNFTNVRVVHKTKREXXXXXXXXXXXXXXXXVLVFMDSHCTVGVKWLPPLLEPIKENYKTVTCPFIDINDTDTSLY-SQDEGARGAFDWNFNYTRLP----RLHNNKTDPEDPFDNPIMQGRIFAITRKWFWELGGYDEGLEIWGGEQFELSFKIWMCGGRMVNVPCSRIRCIFKDIYSFDFIHDDIK-IRKNYKRIAEIWMDNWKKFIYQRHLEEYSSFDCGDISXXXXXXXXXNCKSFDWFMENVAYDILYLYPPITVSEKLNCSITLESDDSICVDSKYRKQGDRVGIDQCNQIGRSEKNKEQRFSFTSDFEIRPGQRNLCFDYRNSSETLMLSQCDLMNPNQKWEYNSTSHQITNIPSQKCI 1638
            DQE ++ L  IN             N    + ++L R++ ++++  CK   +   LP+ SI+I F++  W TL++T   ++ RSPR L+ EIL++DD ++ + ++ K+  Y+      VR++   +R GLI+ARL GA   +G+V+ F+D+HC   V WL PLL  IKE+ K V CP ID+   +T  Y +  +   G F+W  N+   P     +   K D   P   P M G +F+I R +F E+G YD G++IWGGE  E+SF+IW CGG +  V CS +  +F+    + F     + I KN +R+AE+WMD +K F Y          D GD+S +K L++ L CK F W++EN+  D        ++ E  N       + + CVD+  RK+ ++VG   C+ +G       Q FS+T+D EIR    +LC D    +  +++ +C  M  NQ +EY++    + ++ S +C+
Sbjct:   70 DQEKMKELFKINQF-----------NLMASDMIALNRSLPDVRLDGCKTKVYPDDLPNTSIVIVFHNEAWSTLLRTVHSVINRSPRHLLVEILLVDDASERDFLKKKLEDYVKTLEVPVRILRMEQRSGLIRARLRGAAATRGQVITFLDAHCECTVGWLEPLLSRIKEDRKAVVCPIIDVISDETFEYMAGSDMTYGGFNWKLNFRWYPVPQREMDRRKGDRTLPVRTPTMAGGLFSIDRSYFEEIGTYDPGMDIWGGENLEMSFRIWQCGGSLEIVTCSHVGHVFRKATPYSFPGGTGQVINKNNRRLAEVWMDEFKDFFYIIS-PGVVRVDYGDVSARKALREALQCKPFSWYLENIYPDSQIPRRYFSLGEIRNV------ETNQCVDNMGRKENEKVGFFNCHGMG-----GNQVFSYTADKEIR--TDDLCLDVSRLNGPVVMLKCHHMKGNQMFEYDAERLTLLHVNSNQCL 523          

Query:  358 CKWLRHNKTLPSVSIIITFYDSDWEXXXXXXXXXXXXSPRRLIKEXXXXXXXXXXXXMRSKMNAYISKNFTNVRVVHKTKREXXXXXXXXXXXXXXXXVLVFMDSHCTVGVKWLPPLLEPIKENYKTVTCPFIDINDTDTSLY-SQDEGARGAFDWNFNYTRLP----RLHNNKTDPEDPFDNPIMQGRIFAITRKWFWELGGYDEGLEIWGGEQFELSFKIWMCGGRMVNVPCSRIRCIFKDIYSFDFIHDDIK-IRKNYKRIAEIWMDNWKKFIYQRHLEEYSSFDCGDISXXXXXXXXXNCKSFDWFMENVAYDILYLYPPITVSE---KLNCSITLESDDSICVDSKYRKQGDRVGIDQCNQIGRSEKNKEQRFSFTSDFEIRPGQRNLCFDYRNSSETLMLSQCDLMNPNQKWEYNSTSHQI 1611
            CK   +   LP  S++I F++  W TL++T   ++ RSPR +++EI+++DD ++ + ++S +  Y SK    V +V    R GLI+ARL GA +++G+V+ F+D+HC     WL PLL  IK + K V CP ID+   +T  Y +  +   G F+W  N+   P     +   K D   P  +P M G +FAI R +F E+G YD G++IWGGE  E+SF+IW CGG +  V CS +  +F+    + F     + I KN +R+AE+WMDN+K F Y       +  + GD+S++K L+ +L CK F WF+ENV       YP   +      L     +E++   C+D+  RK+ +++GI  C+ +G       Q FS+T+D E+R    +LC D    +  +++ +C  M  NQ W+Y+    ++
Sbjct:    1 CKTKVYPDGLPKTSVVIVFHNEAWSTLLRTVHSIIGRSPRHMLEEIILVDDASERDFLKSPLEEYASKLPVPVHIVRMESRSGLIRARLRGAAVSRGQVITFLDAHCECTTGWLEPLLARIKADRKNVVCPIIDVISDETFEYLAGSDMTYGGFNWKLNFRWYPVPQSEMDRRKGDRTIPVRSPTMAGGLFAIDRDYFQEIGTYDAGMDIWGGENLEMSFRIWQCGGTLEIVTCSHVGHVFRKATPYTFPGGTGQVINKNNRRLAEVWMDNFKDFFYIIS-PGVTKVEYGDVSQRKALRDRLKCKPFSWFLENV-------YPNSQIPRHYYSLGEVRNVETNQ--CLDNMGRKENEKIGIFNCHSMG-----GNQVFSYTADKELR--TDDLCLDVSRMNGPVLMLKCHHMKGNQLWDYDQQMQKL 410          

Query:  529 MRSKMNAYISKNFTNVRVVHKTKREXXXXXXXXXXXXXXXXVLVFMDSHCTVGVKWLPPLLEPIKENYKTVTCPFIDINDTDTSLY-SQDEGARGAFDWNFNYTRLP----RLHNNKTDPEDPFDNPIMQGRIFAITRKWFWELGGYDEGLEIWGGEQFELSFKIWMCGGRMVNVPCSRIRCIFKDIYSFDFIHDDIK-IRKNYKRIAEIWMDNWKKFIYQRHLEEYSSFDCGDISXXXXXXXXXNCKSFDWFMENVAYDILYLYPPITVSEKLNCSITLESDDSICVDSKYRKQGDRVGIDQCNQIGRSEKNKEQRFSFTSDFEIRPGQRNLCFDYRNSSETLMLSQCDLMNPNQKWEYNSTSHQITNIPSQKCI 1638
            ++  +  Y+ K  T VR++   +R GLI+ARL GA  A+G+V+ F+D+HC     WL PLL  IKE+ + V CP ID+   +T  Y +  +   G F+W  N+   P     +   K D   P   P M G +FAI R +F E+G YD G++IWGGE  E+SF+IW CGG +  V CS +  +F+    + F     + I KN +R+AE+WMD +K F Y       +  + GD+S +K L+++L C  F W++ENV  D        ++ E  N    +E++   C+D+  RK+ ++VGI  C+ +G       Q FS+T++ E+R    +LC D    S  +M+ +C  +  NQ W Y+     + ++ S +C+
Sbjct:    7 LKKPLEDYVRKLETPVRLLRMAQRSGLIRARLRGAAAAQGQVITFLDAHCEATTGWLEPLLARIKEDRRAVVCPVIDVISDETFEYLTGSDMTYGGFNWKLNFRWYPVPQREMDRRKGDRTLPVRTPTMAGGLFAIDRDYFQEIGTYDPGMDIWGGENLEMSFRIWQCGGSLEIVTCSHVGHVFRKATPYTFPGGTGQVINKNNRRLAEVWMDEFKGFFYVIS-PGVTKVEYGDVSARKALRERLKCMPFSWYLENVYPDSQIPRHYYSLGEIRN----METNQ--CLDNMGRKENEKVGIFNCHGMG-----GNQVFSYTAEQELR--SDDLCLDVSRLSGPVMMLKCHHLKGNQLWHYDREKMTLRHVNSNQCL 368          

Query:  295 NSFEEEKVSLYRTINELKITKCKWLRHN-KTLPSVSIIITFYDSDWEXXXXXXXXXXXXSPRRLIKEXXXXXXXXXXXXMRSKMNAYISKNFTNVRVVHKTKREXXXXXXXXXXXXXXXXVLVFMDSHCTVGVKWLPPLLEPIKENYKTVTCPFIDINDTDTSLYSQDEGAR--GAFDWN--FNYTRLP-RLHNNKTDPEDPFDNPIMQGRIFAITRKWFWELGGYDEGLEIWGGEQFELSFKIWMCGGRMVNVPCSRIRCIFKDIYSFDFIHDDIKIRKNYKRIAEIWMDNWKKFIYQRHLEEYSSFDCGDISXXXXXXXXXNCKSFDWFMENVAYDILYLYPPITVSEKLNCSITLESDDSI---CVD----SKYRKQGDRVGIDQCNQIGRSEKNKEQRFSFTSDFEIRPGQRN--LCFDYRNSSETLMLSQCDLMNP----NQKWEYNSTSHQITNIPSQKCI 1638
            N +  +++SL+R + E     C+  ++N + LP+ S++I FY+  W TL++T   +L  SP  L+ EI+++DD +D   +R ++  YI+     VR+V   KREGL++ARLLGA +A G VL F+D HC   V WL PLLE I E    V CP ID+ + +T  Y  + G    G FDW   F +  +P      +  P D   +P M G +FA+++K+F  LG YD G+E+WGGE  E SF+IW CGG +   PCS +  +F     +       K   N  R AE+WMD +K+  Y R+         GD+++++ L+++L CK+F WF+ENV       YP I V E       +  +  +   C D     + +  G R+ +  C+ +G++     Q F +TS+ EIR   R    C    N  + L +  C   N     NQK+++      I +I +QKC+
Sbjct:   56 NIYVSDRISLHRQLPEKWNPLCREKKYNYRQLPTTSVVIAFYNEAWSTLLRTVHSVLETSPDALLNEIILVDDYSDREHLRDRLEQYIA-TLRKVRLVRARKREGLVRARLLGAGVATGDVLTFLDCHCECHVGWLEPLLERIAEEESAVVCPVIDVIEWNTFEYMGNAGEPQIGGFDWRLVFTWHTVPGHEQKRRKSPIDVIRSPTMAGGLFAVSKKYFDYLGTYDTGMEVWGGENLEFSFRIWQCGGTLEVHPCSHVGHVFPKQAPY----SRSKALANSVRAAEVWMDGYKELYYHRNPHARME-PFGDVTERRNLRERLQCKTFKWFLENV-------YPDIHVPEDRPGKFGMLKNRGLSNYCFDYNPPDENQVTGQRIILYGCHGMGQN-----QFFEYTSEQEIRYNTRQPEACAAVDNGMDYLTMYYCHSKNSPVTENQKFDFREDG-SIFHILTQKCL 503          

Query:  313 KVSLYRTINELKITKCKWLRHNKTLPSVSIIITFYDSDWEXXXXXXXXXXXXSPRRLIKEXXXXXXXXXXXXMRSKMNAYISKNFTN-VRVVHKTKREXXXXXXXXXXXXXXXXVLVFMDSHCTVGVKWLPPLLEPIKENYKTVTCPFIDINDTDTSLYSQDEGARGAFDWNFNYTRLPRLHNNKTDPED---PFDNPIMQGRIFAITRKWFWELGGYDEGLEIWGGEQFELSFKIWMCGGRMVNVPCSRIRCIFKDIYSFDFIHDDIKIRKNYKRIAEIWMDNWKKFIYQRHLEEYSSFDCGDISXXXXXXXXXNCKSFDWFMENVAYDILYLYP--PITVSEKLN 1335
            ++  +RTI + +  +C    +   LP+ S++I FY+     L++T   +  R+P  L+ E+L++DD +D  D+R  +   + + F   V++V   KREGLI+ R++GA  A G VLVF+DSHC V V WL PLL  + EN  TV CP IDI + DT LYS     RG F+W  ++   P   +  + P+    P  +P M G +FA+ RK+F +LG YD G++IWGGE  E+SF+IWMCGG +  +PCSRI  IF+    +        + +N  R+A +W+D +K+  Y     E    + GD+S++K L+++L C+ F W+++NV  +I    P  P  V  K++
Sbjct:   28 RLDPHRTIPDTRHPRCATKSYPAQLPTASVVICFYNEAVSALLRTVHSVTERTPPALLHEVLLVDDFSDLVDLREGLEKELKEKFPKKVKLVRNEKREGLIRGRMVGANHATGDVLVFLDSHCEVNVAWLEPLLARVAENPSTVVCPIIDIVNPDTFLYSASPLVRGGFNWGLHFRWDPVPSSLLSGPDGEMAPIKSPTMAGGLFAMDRKYFNKLGQYDGGMDIWGGENLEISFRIWMCGGSLEIIPCSRIGHIFRKRRPYGSPAGADTMSRNSLRLAHVWLDEYKEQ-YLALRPELREREYGDVSERKALRERLGCRPFRWYLQNVYPEIEVGRPQLPQAVLSKMH 373          

Query:  295 NSFEEEKVSLYRTINELKITKCKWLRHN-KTLPSVSIIITFYDSDWEXXXXXXXXXXXXSPRRLIKEXXXXXXXXXXXXMRSKMNAYISKNFTNVRVVHKTKREXXXXXXXXXXXXXXXXVLVFMDSHCTVGVKWLPPLLEPIKENYKTVTCPFIDINDTDT-SLYSQ-DEGARGAFDW--NFNYTRLPRLHNNKTDPE-DPFDNPIMQGRIFAITRKWFWELGGYDEGLEIWGGEQFELSFKIWMCGGRMVNVPCSRIRCIFKDIYSFDFIHDDIKIRKNYKRIAEIWMDNWKKFIYQRHL----EEYSSFDCGDISXXXXXXXXXNCKSFDWFMENVAYDILYLYPPITVSE---KLNCSITLESDDSICVD---SKYRKQGDRVGIDQCNQIGRSEKNKEQRFSFTSDFEIR-PGQRNLCFDYRNSSETLMLSQC 1557
            N +  +++SL+R I + ++ +CK  + + + LP+ S++I FY+  W TL++T   +L  SP  L++EI+++DD +D   ++S +  YIS     VR+V  T+REGL++ARLLGA  A G+VL F+D HC     W+ PLL+ I E    V CP ID  D +T   Y Q  E A G FDW   F +  +P    ++     +P  +P M G +FA+++K+F  +G YD+G+E+WGGE  ELSF++W CGG +   PCS +  +F     +       +  +N  R AE+WMD++K+  Y R+     E+Y     GD+S++K L++KL CKSF+W+++N+       YP + V E     + +I  +   S C+D         G  + +  C+  G       Q F +T+  ++R      LC + R+    + +  C
Sbjct:  108 NIYLSDRISLHRHIPDGRMYECKAQKFDYRRLPTTSVVIAFYNEAWSTLLRTVHSVLESSPAVLLREIILVDDFSDRAYLKSPLEDYIS-TLERVRLVRTTQREGLVRARLLGATHATGQVLTFLDCHCECVPGWIEPLLQRIWEKETAVVCPVIDTIDWNTFEFYMQTSEPAIGGFDWRLTFQWHGVPEHERSRRASRIEPIQSPTMAGGLFAVSKKYFDHIGTYDQGMEVWGGENLELSFRVWQCGGSLEVHPCSHVGHVFPKKAPY----PRPRFLQNTVRAAEVWMDSYKEHFYNRNPPGRKEKY-----GDLSERKTLREKLGCKSFEWYLKNI-------YPDLHVPEDRPGFHGAIQNKGIQSECIDYNAPDNNPTGAMLSLYPCHGQG-----GNQFFEYTTRKDLRFNSATELCAEVRDGKPQVAMRHC 523          

Query:  295 NSFEEEKVSLYRTINELKITKCKWLRHNKTLPSVSIIITFYDSDWEXXXXXXXXXXXXSPRRLIKEXXXXXXXXXXXXMRSKMNAYISKNFTNVRVVHKTKREXXXXXXXXXXXXXXXXVLVFMDSHCTVGVKWLPPLLEPIKENYKTVTCPFIDINDTDTSLYS-QDEGARGAFDWNFNYTRL---PRLHNNKTDPEDPFDNPIMQGRIFAITRKWFWELGGYDEGLEIWGGEQFELSFKIWMCGGRMVNVPCSRIRCIFKDIYSFDFIHDDIKIRKNYKRIAEIWMDNWKKFIYQRHLEEYSSFDCGDISXXXXXXXXXNCKSFDWFMENVAYDILYLYPPITVSEKL-NCSITLESDDSICVDSKYRKQGDRVGIDQCNQIGRSEKNKEQRFSFTSDFEIRPGQRNLCFDYRNS--SETLMLSQCDLMNPNQKWEYNSTSHQ 1608
            N F  +++SL RTI++ +   CK   +   LP  S++I F++  W TLM+T   +LLRSP  +++EI+++DD ++ + ++ K++ Y +K    +++V   +R GLIKAR++GA  A G+V++F+D+HC     WLPPLLE I  N +T  CP ID  D  T  Y   D   RG F+W F+Y      P     + DP     +P+M G +FAI R++F ELG YD G+ IWGGEQ+E+SFK+W CGG++ N+PCSR+  +++    + +   D  +  N++R+AE+WMD +K ++Y +   E  S D GDIS +  L+++L CKSF W++ENVA D        TV  KL  C        ++C+DS  RK G  VG+  C+ +G +     Q F +T   E+R  +   CFD   S     +    C  M  NQ++ +     +
Sbjct:   29 NQFVSDQISLERTISDTRHQACKQRSYPINLPKASVVIVFHNEGWSTLMRTVHTVLLRSPPHMLQEIVMVDDFSNKDFLKQKLDDY-TKKLGKIKIVRTKERVGLIKARVIGANNAVGEVVIFLDAHCECNKGWLPPLLERIALNRRTAVCPTIDFIDHKTFQYKPMDPYIRGTFNWRFDYKERAVRPEEMAKRRDPTQEVKSPVMAGGLFAINREFFSELGQYDPGMFIWGGEQYEISFKLWQCGGQLENIPCSRVGHVYRHHVPYTYPKHDATL-VNFRRVAEVWMDEYKDWLYDKR-PEIKSVDYGDISDRIALRKRLKCKSFKWYLENVAND--------TVKTKLCACFQVRNQGKNMCLDSMGRKDG-HVGLASCHNMGGN-----QAFQYTYIRELRTDE--TCFDVHESFPGAKVHFFPCHEMKGNQEFLFTEVGRR 454          

Query:  295 NSFEEEKVSLYRTINELKITKCKWLRHNKTLPSVSIIITFYDSDWEXXXXXXXXXXXXSPRRLIKEXXXXXXXXXXXXMRSKMNAYISKNFTNVRVVHKTKREXXXXXXXXXXXXXXXXVLVFMDSHCTVGVKWLPPLLEPIKENYKTVTCPFIDINDTDTSLYSQDEGARGAFDWNFNYTRLPRLHNNKTDPED---PFDNPIMQGRIFAITRKWFWELGGYDEGLEIWGGEQFELSFKIWMCGGRMVNVPCSRIRCIFKDIYSFDFIHDDIKIRKNYKRIAEIWMDNWKKFIYQ-RHLEEYSSFDCGDISXXXXXXXXXNCKSFDWFMENV-------------AYDILYLYPPITVSEKLNCSITLES--DDSICVDSKYRKQGDRVG--IDQCNQIGRSEKNKEQRFSFTSDFEIRPGQRNLCFDYRN--SSETLMLSQCDLMNPNQKWEYNSTSHQITNIPSQKCI 1638
            N     ++SL+RTI + +   C+   + K LP  SI+I FY+  W  L++T   +L R+P + + EI+++DD ++  +++SK++ Y+S     +R+V   KREGLI+ R++GA+ A G+VLVF+DSHC V + WL PLL+ I ++ K V CP ID+  +DT  YS     RG F+W  ++T  P   +    PED   P  +P M G +FA+ R++F +LG YD G++IWG E  E+SF+IWMCGG +  +PCSR+  +F+    +        + +N  R+AE+W+D +KK+ YQ RH  E   F  GDIS++ KL++ L CKSF+W+++N+             A+  +   P + + +     I L++  DD  C+DS       +    I QC      E  K + +S   D E++  +  LC +     S   L L +C      Q+W++ +    + +  +  C+
Sbjct:   24 NLLISNRLSLHRTIKDTRHELCRGKTYPKNLPVASIVICFYNEAWTILLRTIHSVLDRTPHQFLHEIILVDDFSNMLELKSKLDRYLS-TMPKIRIVRNNKREGLIRGRIIGAEAATGQVLVFLDSHCEVNINWLQPLLQHIHDDQKAVACPVIDVISSDTFEYSSSPMVRGGFNWGLHFTWEPIPPSLLVKPEDYVKPIRSPTMAGGLFAVDREYFTQLGKYDSGMDIWGAENLEISFRIWMCGGSLDILPCSRVGHLFRRFRPYGSDSKGDTMSRNSMRLAEVWLDGYKKYFYQIRHDLEGKKF--GDISQRIKLRKSLQCKSFEWYLKNIYPELKPPGQPGGGAFYPIDRRPQVVIWKGKVICIQLQTSFDDGYCLDSPGHPSEKKASAVIHQC------ESTKSRFWSLNEDGELKI-ESLLCLEASGYQSKLGLRLMKCHAQGGGQQWKFLNKKSVLYHPATGLCL 484          

Query:  295 NSFEEEKVSLYRTINELKITKCKWLR--HNKTLPSVSIIITFYDSDWEXXXXXXXXXXXXSPRRLIKEXXXXXXXXXXXXMRSKMNAYISKNFTNVRVVHKTKREXXXXXXXXXXXXXXXXVLVFMDSHCTVGVKWLPPLLEPIKENYKTVTCPFIDINDTDTSLYSQDE--GARGAFDWN--FNYTRLPRLHNNK-TDPEDPFDNPIMQGRIFAITRKWFWELGGYDEGLEIWGGEQFELSFKIWMCGGRMVNVPCSRIRCIFKDIYS-FDFIHD-DIKIRKNYKRIAEIWMDNWKKFIYQRHLEEYSSFDCGDISXXXXXXXXXNCKSFDWFMENVAYDILYLYPPITVSEKLNCSITLESDDSICVDSKYRKQGDRVGIDQCNQIGRSEKNKEQRFSFTSDFEIRPGQRNLCFDYRNS--SETLMLSQCDLMNPNQKWEYNSTSHQITNIPSQKCI 1638
            N    +++SL R + +++  KCK     + + LP+ S+II F++     L++T   +L  SP RLI +I+++DD ++ +D++  +  +IS     V+++    R+GL+ ARL GA+ A+G+VL F+DSHC     WL PLL  I E+ + V CP I++ + D   Y   +    RG F W+  F +  +P     +  D  D   +P M G +FAI +K+F++LG YD  +EIWGGE  E+SF+IWMCGG++  VPCSR+  +F+   S + F       + +N+ R+AE+WMD +K   Y++  EE  + D GDIS +  L+++L CKSF W+++N+  D+    PP +    L        + S+C+D+   K   RVG+  C+ +G +     Q F+ T   EI     + C D  N      + +  C  +  NQ+W++N     I ++ ++ C+
Sbjct:   29 NVMLSDRISLDRRLKDVRGPKCKRKHKLYPRALPTTSVIICFHNEALSVLLRTVHSVLNESPPRLIADIILVDDYSEYDDLKQPLIDHISM-LNKVKLIRMPSRQGLVPARLRGAEEARGEVLTFLDSHCEATPGWLEPLLVRIAEDRRNVVCPVIEVINADDFRYQASDVIHERGGFTWDLFFTWKAIPEAEKKRRKDETDYIRSPTMAGGLFAIHKKYFYDLGSYDSKMEIWGGENLEMSFRIWMCGGQLEIVPCSRVGHVFRKYTSPYKFPKGTTTTLARNFNRLAEVWMDEYKDHYYRKKTEEERNVDIGDISDRVALRKRLGCKSFKWYLDNIYPDMTNKLPPKSY---LYSHQIRNKESSLCLDTLGEKNIKRVGLYTCHGMGGN-----QFFTLTKSNEILFND-DKCLDSPNGDPGSYVEMITCHGLKGNQEWKHNKRMGTIVHVWTENCL 477          

Query:  184 KNEHKLENHG----LSDQENIRNLSNINLMMKRMNSTRRFNNSFE---EEKVSLYRTINELKITKCKWLRHN---KTLPSVSIIITFYDSDWEXXXXXXXXXXXXSPRRLIKEXXXXXXXXXXXXMRSKMNAYISKNFTNVRVVHKTKREXXXXXXXXXXXXXXXXVLVFMDSHCTVGVKWLPPLLEPIKENYKTVTCPFIDINDTDTSLYSQDEGA--RGAFDWN--FNYTRLPRLHNN-KTDPEDPFDNPIMQGRIFAITRKWFWELGGYDEGLEIWGGEQFELSFKIWMCGGRMVNVPCSRIRCIFKDIYSFDFIHDDIK--IRKNYKRIAEIWMDNWKKFIYQRHLEEYSSFDCGDISXXXXXXXXXNCKSFDWFMENVAYDILY--LYPPITVSEKLNCSITLESDDSICVDSKYRK--QGDRVGIDQCNQIGRSEKNKEQRFSFTSDFEIRPGQRNLCFDYRNS--SETLMLSQCDLMNPNQKWEYNSTSHQITNIPSQKCI 1638
            +N H+L   G    L  +EN           K++      N+SF     +K+SL RT+++++  +CK  +HN     LP+ S+II F+      L++T   ++ R+P  L+ E++++DD + +  +   ++ ++++ FT V+V+   KREGL++ARL GA  AKG VL F+DSHC     W  PLL  I  + + V CP I++ + DT  Y     A  RG F W+  F +  +P      + D  DP   P M G +F+I R++F+++G YDE ++IWGGE  ELSF++WMCGGR+  V CSR+  +F+   S     D ++  + KN+ R+AE+WMD +K   Y +  +  +S D GDISK+ +L+++L CKSF W++ N+  D+    L PP    E  N S       + C+DS   K     RVGI  C+  G ++ +K        + E        CFD   +     + L +C  M  NQ+W+++     + +  +Q+C+
Sbjct:    2 RNTHQLGGGGKPAFLESEEN-----------KKLAEKYFANHSFNWLLSDKISLDRTLDDVRSERCK-AKHNTYPAKLPTTSVIICFHKERLSVLLRTVHSVINRTPPELLAEVIVVDDFSQDAKLGKPLDDHVAQ-FTKVKVLRMKKREGLVRARLQGANTAKGDVLTFLDSHCEATPGWAEPLLARIAADRRNVVCPAIEVINADTFAYQGSTNADQRGGFSWDLFFKWKGIPPEEQKLRNDDSDPIRTPTMAGGLFSIHRQYFFDIGSYDEEMDIWGGENLELSFRVWMCGGRLEIVTCSRVGHVFRKYTSPYKFPDGVERTLTKNFNRLAEVWMDEYKDLYYNKKPQAKNS-DYGDISKRLELRKRLKCKSFKWYINNIYPDVQMPELDPPAR-GEVRNPS------SNQCLDSLGAKPEHNARVGIYTCHGQGGNQVSKYMPRELIFEEEN-------CFDVSKTHPGAPVELMKCHGMRGNQEWKHDREKGTLMHFTTQQCL 481          

Query:  295 NSFEEEKVSLYRTINELKITKCKWLRHNKTLPSVSIIITFYDSDWEXXXXXXXXXXXXSPRRLIKEXXXX---XXXXXXXXMRSKMNAYISKNFTNVRVVHKTKREXXXXXXXXXXXXXXXXVLVFMDSHCTVGVKWLPPLLEPIKENYKTVTCPFIDINDTDTSLYSQDEGA--RGAFDW--NFNYTRLPRLHNNKTDPE-DPFDNPIMQGRIFAITRKWFWELGGYDEGLEIWGGEQFELSFKIWMCGGRMVNVPCSRIRCIFKDIYSFDFIHDDIKIRKNYKRIAEIWMDNWKKFIYQRHLEEYSSFDCGDISXXXXXXXXXNCKSFDWFMENVAYDILY--LYPPITVSEKLNCSITLESDDSICVDSKYRKQ-GDRVGIDQCNQIGRSE 1443
            N     KV+L R+I + +   C  L +   LP+ S+II F++  W TL++T   +L RSP  L++EI+++           + SK+ +YIS+ FT V+++   KREGLI+ARL+GAK AKG+VLVF+DSHC   + WL PLL  I EN   V  P I++ D  T  Y+ + GA  RG F+W   F +  +P     +   + DP  +P M G +FAI + +F+E+G YD  +  WGGE  E+SF+IWMCGG +  +PCS++  +F++   +     +  I +N  R+AE+WMD++KK  Y     +    D GD+S +K L+++L CKSF W+++NV  ++    LY PI   E  N         + C+D+  + + G   G+  C+ +G ++
Sbjct:   16 NELASSKVALDRSIPDNRPQSCLSLSYPTKLPTASVIIIFHNEAWSTLLRTVHSVLARSPPYLLREIVLVDDHSRLDTYGHLGSKLESYISQ-FTKVQLIRAPKREGLIRARLIGAKQAKGEVLVFLDSHCEANLGWLEPLLARIGENRSIVVTPDIEVIDLRTFGYTHEHGANNRGIFNWELTFKWRGIPEYERRRRKSDSDPIRSPTMAGGLFAIDKSYFYEIGSYDTEMSFWGGENVEISFRIWMCGGSLEIIPCSKVGHVFRESQPYKI--GEGAIDRNNMRLAEVWMDDYKKIFYAMR-PQLKGKDYGDVSGRKALRERLMCKSFKWYLDNVISELAIPDLY-PIGRGEIRNLGT------NTCLDTLAKNEAGGEPGMYMCHGMGNNQ 398          

Query:  268 RMNSTRRFN--NSFEEEKVSLYRTINELKITKCKWLRHNKTLPSVSIIITFYDSDWEXXXXXXXXXXXXSPRRLIKEXXXXXXXXXXXXMRSKMNAYISKNFTNVRVVHKTKREXXXXXXXXXXXXXXXXVLVFMDSHCTVGVKWLPPLLEPIKENYKTVTCPFIDINDTDTSLYSQDEG--ARGAFDWNFNYTRLP-RLHNNKTDPEDPFDNPIMQGRIFAITRKWFWELGGYDEGLEIWGGEQFELSFKIWMCGGRMVNVPCSRIRCIFKDIYSFDFIHDDIKIRKNYKRIAEIWMDNWKKFIYQRHLEEYSSFDCGDISXXXXXXXXXNCKSFDWFMENVAYDILYLYPPITVSEKLNCSITLESDDSICVDSKYRKQGDRVGIDQCNQIGRSEKN--KEQRFSFTSDFEIRPGQ----RNLCFDYRNSSETLMLSQCDLMNPNQKWEY---NSTSHQITNIPSQKCIXXXXXXXXXXXXXXXXXXTMQKWIIQGCN 1725
            R++   R N  N F  +++SL R++ +++   CK   + + LP+ SIII F++  W +L++T   +L RSP +LI EI+++DD +D + ++  +  Y+ +    VR++   KREGLI+ RLLGA  AKG+V+ F+DSHC   + WLPPLL+ I  N KT+ CP ID+ D D   Y    G   RGAFDW   Y R+P      K DP +PF++P+M G +FA+ RKWFWELGGYD GLEIWGGEQ+E+SFK+WMCGGRM ++PCSR+  I++    +  +   + + +N KR+AE+WMD + +++YQR   EY     GD++ QK+L+  LNCKSF WFM+ VA+D+   YPP+         +   +   +C++SK+   G  + ++ C + GR++ +    Q F+F    +IR G     + +CFD  +    + L  C  M  NQ W Y    S  H ++N     C+  N+    + +N C+ +S  Q+W+ +  N
Sbjct:  102 RVDQAYRENGFNIFVSDRISLNRSVPDIRHPNCKQKLYAERLPNTSIIIPFHNEGWSSLLRTVHSVLNRSPPQLIAEIILVDDFSDKDHLKGALEEYMVR-LPKVRILRTKKREGLIRTRLLGAAAAKGEVITFLDSHCEANINWLPPLLDRIALNRKTIVCPMIDVIDHDNFGYETQAGDAMRGAFDWEMYYKRIPIPAELQKNDPSEPFESPVMAGGLFAVDRKWFWELGGYDTGLEIWGGEQYEISFKVWMCGGRMEDIPCSRVGHIYRKYVPYK-VPGGVSLARNLKRVAEVWMDEYAEYVYQRR-PEYRHLSAGDVAAQKELRSTLNCKSFKWFMKEVAWDLPKHYPPVEPPAAAWGEVR-SAASGLCLESKHFVSGTPIRLESCVK-GRADVSWGHGQVFTFGWREDIRVGDPMHTKKVCFDAVSHHSPVTLYDCHGMRGNQLWRYRKDKSLYHPVSN----SCVDSNASERRVFMNVCNPASASQQWLFEKTN 592          

Query:  268 RMNSTRRFN--NSFEEEKVSLYRTINELKITKCKWLRHNKTLPSVSIIITFYDSDWEXXXXXXXXXXXXSPRRLIKEXXXXXXXXXXXXMRSKMNAYISKNFTNVRVVHKTKREXXXXXXXXXXXXXXXXVLVFMDSHCTVGVKWLPPLLEPIKENYKTVTCPFIDINDTDTSLYSQDEG--ARGAFDWNFNYTRLPRLHNNKTD-PEDPFDNPIMQGRIFAITRKWFWELGGYDEGLEIWGGEQFELSFKIWMCGGRMVNVPCSRIRCIFKDIYSFDFIHDDIKIRKNYKRIAEIWMDNWKKFIYQRHLEEYSSFDCGDISXXXXXXXXXNCKSFDWFMENVAYDILYLYPPITVSEKLNCSITLESDDSICVDSKYRKQGDRVGIDQCNQIGRSEK--NKEQRFSFTSDFEIRPGQ----RNLCFDYRNSSETLMLSQCDLMNPNQKWEY---NSTSHQITNIPSQKCIXXXXXXXXXXXXXXXXXXTMQKWIIQGCNDN 1731
            R++   R N  N +   ++SL R++ +++   C+   + + LP+ +III F++  W +L++T   ++ RSP RL+ EI+++DD +D   ++  +  Y+ K F  VR++   KREGLI+ RLLGA  AKG+V+ F+DSHC   V WLPPLL+ I +N KT+ CP ID+ D D   Y    G   RGAFDW   Y R+P     +TD P +PF++P+M G +FA+ RKWFWELGGYD GLEIWGGEQ+E+SFK+WMCGGRM ++PCSR+  I++    +  +   I + KN KR+AE+WMD + +++YQR   EY     GD+S QK+L+  LNCK+F WFME VA+D+   YPP+         I       +C++ K+   G  + ++ C + GR +   +  Q  +F    +IR G     R +CFD  +    + L  C  M  NQ W Y    S  H ++N     CI  ++    + +N C  +S  Q+W+ +  ND 
Sbjct:  101 RVDQAYRENGFNIYVSNRISLNRSLPDIRHENCRQKLYAEKLPNTTIIIPFHNEGWSSLLRTVHSVINRSPPRLVAEIILVDDFSDKEHLKVALEEYM-KRFPKVRILRTKKREGLIRTRLLGAGAAKGEVITFLDSHCEANVNWLPPLLDRIVQNRKTIVCPMIDVIDHDNFGYDTQAGDAMRGAFDWEMYYKRIPIPAEMRTDDPTEPFESPVMAGGLFAVDRKWFWELGGYDTGLEIWGGEQYEISFKVWMCGGRMEDIPCSRVGHIYRKYVPYK-VPGGISLAKNLKRVAEVWMDEYAEYVYQRR-PEYRHLSAGDMSAQKELRSHLNCKNFRWFMEEVAWDLPKHYPPVEPPAAAWGEIR-SVGSGMCMEIKHFVSGSPIRLESCVK-GRGDVSWSHGQVLTFGWREDIRVGDPMHTRKVCFDAVSHHSPVTLYDCHGMKGNQLWRYRKDKSLFHPVSN----SCIDSSASERRVFMNTCDPTSLSQQWLFERTNDT 593          

Query:  262 MKRMNSTRRFNNSFEEEKVSLYRTINELKITKCKWLRHNKTLPSVSIIITFYDSDWEXXXXXXXXXXXXSPRRLIKEXXXXXXXXXXXXMRSKMNAYISKNFTNVRVVHKTKREXXXXXXXXXXXXXXXXVLVFMDSHCTVGVKWLPPLLEPIKENYKTVTCPFIDINDTDTSLY-SQDEGARGAFDWNFNYTRLP----RLHNNKTDPEDPFDNPIMQGRIFAITRKWFWELGGYDEGLEIWGGEQFELSFKIWMCGGRMVNVPCSRIRCIFKDIYSFDFIHDDIK-IRKNYKRIAEIWMDNWKKFIYQRHLEEYSSFDCGDISXXXXXXXXXNCKSFDWFMENVAYDILYLYPPITVSEKLNCSITLESDDSICVDSKYRKQGDRVGIDQCNQIGRSEKNKEQRFSFTSDFEIRPGQRNLCFDYRNSSETLMLSQCDLMNPNQKWEYNSTSHQITNIPSQKCI 1638
            MK M    +FN     E ++L R++ ++++  CK   +   LP  S++I F++  W TL++T   ++ RSPR L++EI+++DD ++ + ++ ++  Y+ +    VRVV   +R GLI+ARL GA ++ G+V+ F+D+HC   + WL PLL  IK++ +TV CP ID+   DT  Y +  +   G F+W  N+   P     +   K D   P   P M G +F+I R +F E+G YD G++IWGGE  E+SF+IW CGG +  V CS +  +F+    + F     + I KN +R+AE+WMD +K F Y       +  D GDIS +  L+QKL CK F W++EN+  D        ++ E  N       + + C+D+  RK+ ++VGI  C+ +G       Q FS+T++ EIR    +LC D    +  +M+ +C  +  NQ WEY+     + ++ S +C+
Sbjct:   73 MKEMFKINQFN-LMASEMIALNRSLPDVRLEGCKNKLYPDDLPRTSVVIVFHNEAWSTLLRTVHSVIDRSPRSLLEEIVLVDDASERDFLKRQLEQYVRRLEVPVRVVRMEQRSGLIRARLKGASISTGQVITFLDAHCECTLGWLEPLLTRIKQDKRTVVCPIIDVISDDTFEYMAGSDMTYGGFNWKLNFRWYPVPQREMDRRKGDRTIPVRTPTMAGGLFSIDRDYFQEIGTYDAGMDIWGGENLEISFRIWQCGGTLEIVTCSHVGHVFRKATPYTFPGGTGQIINKNNRRLAEVWMDEFKNFFYIIS-PGVTKVDYGDISTRTSLRQKLQCKPFSWYLENIYPDSQIPRHYYSLGEIRNV------ETNQCLDNMARKENEKVGIFNCHGMG-----GNQVFSYTANKEIR--TDDLCLDVSKLNGPVMMLKCHHLKGNQLWEYDPVKLTLVHVNSNQCL 522          

Query:  262 MKRMNSTRRFNNSFEEEKVSLYRTINELKITKCKWLRHNKTLPSVSIIITFYDSDWEXXXXXXXXXXXXSPRRLIKEXXXXXXXXXXXXMRSKMNAYISKNFTNVRVVHKTKREXXXXXXXXXXXXXXXXVLVFMDSHCTVGVKWLPPLLEPIKENYKTVTCPFIDINDTDTSLY-SQDEGARGAFDWNFNYTRLP----RLHNNKTDPEDPFDNPIMQGRIFAITRKWFWELGGYDEGLEIWGGEQFELSFKIWMCGGRMVNVPCSRIRCIFKDIYSFDFIHDDIK-IRKNYKRIAEIWMDNWKKFIYQRHLEEYSSFDCGDISXXXXXXXXXNCKSFDWFMENVAYDILYLYPPITVSEKLNCSITLESDDSICVDSKYRKQGDRVGIDQCNQIGRSEKNKEQRFSFTSDFEIRPGQRNLCFDYRNSSETLMLSQCDLMNPNQKWEYNSTSHQITNIPSQKCI 1638
            MK M    +FN     E ++L R++ ++++  CK   +   LP  S++I F++  W TL++T   ++ RSPR L++EI+++DD ++ + ++ ++  Y+ +    VRVV   +R GLI+ARL GA ++ G+V+ F+D+HC   + WL PLL  IK++ +TV CP ID+   DT  Y +  +   G F+W  N+   P     +   K D   P   P M G +F+I R +F E+G YD G++IWGGE  E+SF+IW CGG +  V CS +  +F+    + F     + I KN +R+AE+WMD +K F Y       +  D GDIS +  L+QKL CK F W++EN+  D        ++ E  N       + + C+D+  RK+ ++VGI  C+ +G       Q FS+T++ EIR    +LC D    +  +M+ +C  +  NQ WEY+     + ++ S +C+
Sbjct:   73 MKEMFKINQFN-LMASEMIALNRSLPDVRLEGCKNKLYPDDLPRTSVVIVFHNEAWSTLLRTVHSVIDRSPRSLLEEIVLVDDASERDFLKRQLEQYVRRLEVPVRVVRMEQRSGLIRARLKGASISTGQVITFLDAHCECTLGWLEPLLTRIKQDKRTVVCPIIDVISDDTFEYMAGSDMTYGGFNWKLNFRWYPVPQREMDRRKGDRTIPVRTPTMAGGLFSIDRDYFQEIGTYDAGMDIWGGENLEISFRIWQCGGTLEIVTCSHVGHVFRKATPYTFPGGTGQIINKNNRRLAEVWMDEFKNFFYIIS-PGVTKVDYGDISTRTSLRQKLQCKPFSWYLENIYPDSQIPRHYYSLGEIRNV------ETNQCLDNMARKENEKVGIFNCHGMG-----GNQVFSYTANKEIR--TDDLCLDVSKLNGPVMMLKCHHLKGNQLWEYDPVKLTLVHVNSNQCL 522          

Query:  196 KLENHGLSDQENIRNLSNINLMMKRMNSTRRFNNSFEEEKVSLYRTINELKITKCKWLRHNKTLPSVSIIITFYDSDWEXXXXXXXXXXXXSPRRLIKEXXXXXXXXXXXXMRSKMNAYISKNFTNVRVVHKTKREXXXXXXXXXXXXXXXXVLVFMDSHCTVGVKWLPPLLEPIKENYKTVTCPFIDINDTDTSLY-SQDEGARGAFDWNFNYTRLP----RLHNNKTDPEDPFDNPIMQGRIFAITRKWFWELGGYDEGLEIWGGEQFELSFKIWMCGGRMVNVPCSRIRCIFKDIYSFDFIHDDIK-IRKNYKRIAEIWMDNWKKFIYQRHLEEYSSFDCGDISXXXXXXXXXNCKSFDWFMENVAYDILYLYPPITVSEKLNCSITLES-DDSICVDSKYRKQGDRVGIDQCNQIGRSEKNKEQRFSFTSDFEIRPGQRNLCFDYRNSSETLMLSQCDLMNPNQKWEYNSTSHQITNIPSQKCI 1638
            K  N    DQE ++ L  IN             N    + ++L R++ ++++  CK   +   LP+ SI+I F++  W TL++T   ++ RSPR L+ EI+++DD ++ + ++ K+  Y+      V+++   +R GLI+ARL GA    G+V+ F+D+HC     WL PLL  IKE+   V CP ID+   +T  Y +  +   G F+W  N+   P     +   K D   P   P M G +F+I + +F E+G YD G++IWGGE  E+SF+IW CGG +  V CS +  +F+    + F     + I KN +R+AE+WMD +K F Y          D GD+S +K L++ L CK F W++EN+       YP   +  +      + + + + CVD+  RK+ ++VG   C+ +G       Q FS+T+D EIR    +LC D    +  +++ +C  M  NQ +EY++  H   +I +Q C+
Sbjct:   62 KAVNIAKDDQEKMKELFKINQF-----------NLMASDMIALNRSLPDVRLDGCKTKVYADDLPTTSIVIVFHNEAWSTLLRTVHSVISRSPRHLLVEIVLVDDASERDFLKKKLEGYVRTLEVPVKILRMEQRSGLIRARLRGAAATTGQVITFLDAHCECTEGWLEPLLARIKEDRTAVVCPIIDVISDETFEYMAGSDMTYGGFNWKLNFRWYPVPQREMDRRKGDRTLPVRTPTMAGGLFSIDKMYFEEIGSYDPGMDIWGGENLEMSFRIWQCGGSLEIVTCSHVGHVFRKATPYSFPGGTGQVINKNNRRLAEVWMDEFKDFFYIIS-PGVMRVDYGDVSSRKALREALKCKPFAWYLENI-------YPDSQIPRRYYSLGEIRNVETNQCVDNMGRKENEKVGFFNCHGMG-----GNQVFSYTADKEIR--TDDLCLDVSRLNGPVVMLKCHHMKGNQMFEYDAEKHSFLHIITQSCL 523          

Query:   88 MNSRLVISIFVWGLFPWRHNFISSFQIQSALSKNEHKLENHGLSDQENIRNLSNINLMMKRMNSTRRFNNSFEEEKVSLYRTINELKITKCKWLRHNKTLPSVSIIITFYDSDWEXXXXXXXXXXXXSPRRLIKEXXXXXXXXXXXXMRSKMNAYISKNFTNVRVVHKTKREXXXXXXXXXXXXXXXXVLVFMDSHCTVGVKWLPPLLEPIKENYKTVTCPFIDINDTDTSLYSQDEGARGAFDWNFNYTRLPRLHNNKTDPEDPFDNPIMQGRIFAITRKWFWELGGYDEGLEIWGGEQFELSFKIWMCGGRMVNVPCSRIRCIFKDIYSFDFIHDDIKIRKNYKRIAEIWMDNWKKFIYQRHLEEYSSFDCGDISXXXXXXXXXNCKSFDWFMENVAYDILYLYPPITVSEKLNCSITLESDDSICVDSKYRKQGDRVGIDQCNQIGRSEKNKEQRFSFTSDFEIRPGQRNLCFDYRNSSETLMLSQCDLMNPNQKWEYNSTSHQITNIPSQKCIXXXXXXXXXXXXXXXXXXTMQKWIIQ 1716
            MNSRLVISIFVWGLFPWRHNFISSFQIQSALSKNEHKLENHGLSDQENIRNLSNINLMMKRM+STRRFNNSFEEEKVSLYRTINELKITKCKWLRHNKTLPSVSIIITFYDSDWETLMQTTRMLLLRSPRRLIKEILIIDDNADNNDMRSKMNAY+SK+FTNVRVVHKTKREGLIKARLLGAKLAKGKVLVFMDSHCTVGVKWLPPLLEPIKENYKTVTCPFIDINDTDTSLYSQDEGARGAFDWNFNYTRLPRLHNNKTDPEDPFDNPIMQGRIFAITR WFWELGGYDEGLEIWGGEQFELSFKIWMCGGRMVNVPCSRIRCIFKDIYSFDFIHDDIKIRKNYKRIAEIWMDNWKKFIYQRHLEEYSSFDCGDISKQKKLQQKLNCKSFDWFMENVAYDILYLYPPITVSEKLNCSITLESDDSICVDSKYRKQGDRVGIDQCNQIGRSEKNKEQRFSFTSDFEIRPGQRNLCFDYRNSSETLMLSQCDLMNPNQKWEYNSTSHQITNIPSQKCIKVNSKSLLLLVNNCSLSSTMQKWIIQ
Sbjct:    1 MNSRLVISIFVWGLFPWRHNFISSFQIQSALSKNEHKLENHGLSDQENIRNLSNINLMMKRMHSTRRFNNSFEEEKVSLYRTINELKITKCKWLRHNKTLPSVSIIITFYDSDWETLMQTTRMLLLRSPRRLIKEILIIDDNADNNDMRSKMNAYVSKHFTNVRVVHKTKREGLIKARLLGAKLAKGKVLVFMDSHCTVGVKWLPPLLEPIKENYKTVTCPFIDINDTDTSLYSQDEGARGAFDWNFNYTRLPRLHNNKTDPEDPFDNPIMQGRIFAITRNWFWELGGYDEGLEIWGGEQFELSFKIWMCGGRMVNVPCSRIRCIFKDIYSFDFIHDDIKIRKNYKRIAEIWMDNWKKFIYQRHLEEYSSFDCGDISKQKKLQQKLNCKSFDWFMENVAYDILYLYPPITVSEKLNCSITLESDDSICVDSKYRKQGDRVGIDQCNQIGRSEKNKEQRFSFTSDFEIRPGQRNLCFDYRNSSETLMLSQCDLMNPNQKWEYNSTSHQITNIPSQKCIKVNSKSLLLLVNNCSLSSTMQKWIIQ 543          

Query:   88 MNSRLVISIFVWGLFPWRHNFISSFQIQSALSKNEHKLENHGLSDQENIRNLSNINLMMKRMNSTRRFNNSFEEEKVSLYRTINELKITKCKWLRHNKTLPSVSIIITFYDSDWEXXXXXXXXXXXXSPRRLIKEXXXXXXXXXXXXMRSKMNAYISKNFTNVRVVHKTKREXXXXXXXXXXXXXXXXVLVFMDSHCTVGVKWLPPLLEPIKENYKTVTCPFIDINDTDTSLYSQDEGARGAFDWNFNYTRLPRLHNNKTDPEDPFDNPIMQGRIFAITRKWFWELGGYDEGLEIWGGEQFELSFKIWMCGGRMVNVPCSRIRCIFKDIYSFDFIHDDIKIRKNYKRIAEIWMDNWKKFIYQRHLEEYSSFDCGDISXXXXXXXXXNCKSFDWFMENVAYDILYLYPPITVSEKLNCSITLESDDSICVDSKYRKQGDRVGIDQCNQIGRSEKNKEQRFSFTSDFEIRPGQRNLCFDYRNSSETLMLSQCDLMNPNQKWEYNSTSHQITNIPSQKCIXXXXXXXXXXXXXXXXXXTMQKWIIQ 1716
            MNSRLVISIFVWGLFPWRHNFISSFQIQSALSKNEHKLENHGLSDQENIRNLSNINLMMKRM+STRRFNNSFEEEKVSLYRTINELKITKCKWLRHNKTLPSVSIIITFYDSDWETLMQTTRMLLLRSPRRLIKEILIIDDNADNNDMRSKMNAY+SK+FTNVRVVHKTKREGLIKARLLGAKLAKGKVLVFMDSHCTVGVKWLPPLLEPIKENYKT                  DEGARGAFDWNFNYTRLPRLHNNKTDPEDPFDNPIMQGRIFAITR WFWELGGYDEGLEIWGGEQFELSFKIWMCGGRMVNVPCSRIRCIFKDIYSFDFIHDDIKIRKNYKRIAEIWMDNWKKFIYQRHLEEYSSFDCGDISKQKKLQQKLNCKSFDWFMENVAYDILYLYPPITVSEKLNCSITLESDDSICVDSKYRKQGDRVGIDQCNQIGRSEKNKEQRFSFTSDFEIRPGQRNLCFDYRNSSETLMLSQCDLMNPNQKWEYNSTSHQITNIPSQKCIKVNSKSLLLLVNNCSLSSTMQKWIIQ
Sbjct:    1 MNSRLVISIFVWGLFPWRHNFISSFQIQSALSKNEHKLENHGLSDQENIRNLSNINLMMKRMHSTRRFNNSFEEEKVSLYRTINELKITKCKWLRHNKTLPSVSIIITFYDSDWETLMQTTRMLLLRSPRRLIKEILIIDDNADNNDMRSKMNAYVSKHFTNVRVVHKTKREGLIKARLLGAKLAKGKVLVFMDSHCTVGVKWLPPLLEPIKENYKT------------------DEGARGAFDWNFNYTRLPRLHNNKTDPEDPFDNPIMQGRIFAITRNWFWELGGYDEGLEIWGGEQFELSFKIWMCGGRMVNVPCSRIRCIFKDIYSFDFIHDDIKIRKNYKRIAEIWMDNWKKFIYQRHLEEYSSFDCGDISKQKKLQQKLNCKSFDWFMENVAYDILYLYPPITVSEKLNCSITLESDDSICVDSKYRKQGDRVGIDQCNQIGRSEKNKEQRFSFTSDFEIRPGQRNLCFDYRNSSETLMLSQCDLMNPNQKWEYNSTSHQITNIPSQKCIKVNSKSLLLLVNNCSLSSTMQKWIIQ 525          

Query:  154 SSFQIQSALSKNEHKLE--NHGLSDQENIRN-----------LSNINLMMKRMNSTRRFNNSFEEEKVSLYRTINELKITKCKWLRHNKTLPSVSIIITFYDSDWEXXXXXXXXXXXXSPRRLIKEXXXXXXXXXXXXMRSKMNAYISKNFTNVRVVHKTKREXXXXXXXXXXXXXXXXVLVFMDSHCTVGVKWLPPLLEPIKENYKTVTCPFID-INDTDTSLYSQDEGARGAFDWNFNYTRLPRLHNNKTDPEDPFDNPIMQGRIFAITRKWFWELGGYDEGLEIWGGEQFELSFKIWMCGGRMVNVPCSRIRCIFKDIYSFDFIHDDIKIRKNYKRIAEIWMDNWKKFIYQRHLEEYSSFDCGDISXXXXXXXXXNCKSFDWFMENVAYDILYLYPPITVSEKLN-CSITLESDDSICVDSKYRKQGDRVGIDQCNQIGRSEKNKEQRFSFTSDFEIRPGQRNLCFDYRNSSETLMLSQCDLMNPNQKWEYNSTSHQITNIPSQKCIXXXXXXXXXXXXXXX-XXXTMQKWIIQGCN 1725
            +S +I    S ++ K++  NH   D+EN R             +N N   K++  T  +N +   +K+S++R+I +L+I KCKWL+++  LP  SIII F++  W TL++T   +L RSP +L+KEI+++DDN+    +  K+  Y+S++FT VR++   KREGLI+ARLLGA  A G VL+F+DSHC VG+ WLPPLL+PI+++YKT++CPFID I+  D SL  QDEG RGAFDWNF+Y RLPRL  +   PE PF NPIM G +FAI++ WF ELGGYD GL++WGGEQ+ELSFK+WMCGG+MV+VPCSR+  +++    F  +     + +N+KRIAE+WMD+WK++IYQ+H + YSS D GD+++QKKL++ LNC SFDWFM+ +AYD+L  YP     E L+   I  E +  +C D      GD   I  C  +     + EQ  +FT + EI+P +R++C DY    E L +  C  M  NQKW YN  SHQI ++ S+KCI        L +N       + QKWI++  N
Sbjct:   48 TSDEINEVSSDSQIKIDWANHDTIDEENARVGPGEQGIGVYLTANENEKAKQLMETNGYN-ALASDKISVHRSIKDLRINKCKWLKYDNFLPPASIIIPFHNEHWSTLLRTVHSILHRSPDKLVKEIILVDDNSTKEFLGEKLEQYVSEHFTKVRILRTGKREGLIRARLLGANEANGTVLIFIDSHCEVGINWLPPLLQPIRDHYKTISCPFIDVISYNDFSLRPQDEGGRGAFDWNFDYKRLPRLSKDNAHPEKPFYNPIMAGGLFAISKLWFNELGGYDYGLDVWGGEQYELSFKVWMCGGKMVDVPCSRVGHVYRKFNPFAVVGLGNYLARNHKRIAEVWMDDWKQYIYQKHQKVYSSLDPGDLTEQKKLRKALNCTSFDWFMKQIAYDLLEKYPIQKQPENLSQGKIKSEINPHLCFDFNLGNPGDPFRISNCTDV-----SNEQNLAFTWEMEIKPQKRDICLDYPRKGEELTMFSCHGMGGNQKWIYNQNSHQIVHVVSKKCIDYRYNPESLEINIQKCSRKSSQKWILENMN 581          

Query:  295 NSFEEEKVSLYRTINELKITKCKWLRHNKTLPSVSIIITFYDSDWEXXXXXXXXXXXXSPRRLIKEXXXXXXXXXXXXMRSKMNAYISKNFTN-VRVVHKTKREXXXXXXXXXXXXXXXXVLVFMDSHCTVGVKWLPPLLEPIKENYKTVTCPFIDINDTDTSLY-SQDEGARGAFDWNFNYTRLPRLHNNKTDPEDPFDNPIMQGRIFAITRKWFWELGGYDEGLEIWGGEQFELSFKIWMCGGRMVNVPCSRIRCIFKDIYSF-DFIHDDIKIRKNYKRIAEIWMDNWKKFIYQRHLEEYSSFDCGDISXXXXXXXXXNCKSFDWFMENVAYDILYLY----PPITVSEKLNCSITLESDDSICVDSKYRKQGDRVGIDQCNQIGRSEKNKEQRFSFTSDFEIRPGQRNLCFDYRNS--SETLMLSQCDLMNPNQKWEYNSTSHQITNIPSQKCI 1638
            N    +K++L R++ +++   CK + + K+LPSVSIII FY+  W TL++T    L+R+P+ L+KEI+++DD +    ++ K++ YI  NF   VRV+ + KREGLI+ RL GAK A G VL+F+DSHC   + WLPPLL+PI ++Y+TVTCPFID+ D DT  Y +QDEGARGAFDW F Y RLP L  +   P  PF +P+M G +FAI+RKWFWELGGYD GL+IWGGEQ+ELSFKIW CGG+M++ PCSRI  +++    F   ++    I +NYKR+AE+WMD ++K++Y+R    +   + GD++ Q  ++++L CKSF WFM  +A+D+   Y    PP +   ++   +     +S+C+D+K+ K   ++ +  C +   S    EQ+F  T   ++R   R+ C D   +     ++L  C     NQ W+Y   S Q+ ++ +QKC+
Sbjct:  102 NGLASDKMALNRSVKDIRHPDCKKMLYQKSLPSVSIIIPFYEEHWSTLLRTFISALIRAPKGLVKEIILVDDCSTKEFLKDKLDQYIENNFKGIVRVLRQDKREGLIRTRLKGAKNATGDVLIFLDSHCEANINWLPPLLDPIAQDYRTVTCPFIDVLDHDTFEYRAQDEGARGAFDWEFYYKRLPLLPEDLKYPARPFKSPVMAGGLFAISRKWFWELGGYDPGLDIWGGEQYELSFKIWQCGGQMLDTPCSRIAHVYRKYAPFPSVVNIGNFIARNYKRVAEVWMDEYRKYLYRRQ-PSWERENAGDLTAQFAIRERLKCKSFKWFMTEIAFDLEKHYPSVEPPNSADGEVRSKVFNSDGNSLCLDAKFAKSESQIRLAPCVK-DNSRLTGEQKFLLTWHEDLRLKSRDECLDVPQNMFKSPVILYSCHGQKGNQLWKYKLDSKQLYHVVTQKCL 556          

Query:  295 NSFEEEKVSLYRTINELKITKCKWLRHNKTLPSVSIIITFYDSDWEXXXXXXXXXXXXSPRRLIKEXXXXXXXXXXXXMRSKMNAYISKNFTNVRVVHKTKREXXXXXXXXXXXXXXXXVLVFMDSHCTVGVKWLPPLLEPIKENYKTVTCPFIDINDTDTSLY-SQDEGARGAFDWNFNYTRLPRLHNNKTDPEDPFDNPIMQGRIFAITRKWFWELGGYDEGLEIWGGEQFELSFKIWMCGGRMVNVPCSRIRCIFKDIYSFDFIHDDIKIRKNYKRIAEIWMDNWKKFIYQRHLEEYSSFDCGDISXXXXXXXXXNCKSFDWFMENVAYDILYLYPPITVSEKLNCSITLESDD--SICVDSKYRKQGDRVGIDQCNQIGRSEKNKEQRFSFTSDFEIRPGQRNLCFDYRN--SSETLMLSQCDLMNPNQKWEYNSTSHQITNIPSQKCIXXXXXXXXXXXXXXXXXXTMQKWIIQGCN 1725
            + +  +K+S+ R++ +++   CK L++ K+LPSVS+II F+   W  L++T   ++ R+P  LIKE++++DD +    ++  +  ++ +++   +V+    R+GLI+ R+LGAK A G VL+F+DSH    V WLPPLLEPI +NYKTVTCPFID+ + DT  Y SQDEGARG FDWNF+Y R+PR  ++++ P DPF++P+M G +FAI+RKWFWELGGYDEGL+IWGGEQ+E+SFK+W CGG+M++VPCSRI  +++    F        I +N+KR+AE+WMD +K+++Y R      + D  +++ Q  +++KL+CK+F WFM+ VA+D++  YP I  +   +  I L + +  S+C+D K+R  G  VG+  C  +   E   EQ F  +   EI+P  R++C D  +     +++L +C     NQ ++Y   S QI  + S  C++ +  S  + +  C+ + T QKWI    N
Sbjct:  110 DGYASDKISIQRSLRDIRHPACKTLKYLKSLPSVSVIIPFHQEHWSPLIRTVDSVIRRAPLGLIKEVILVDDASRKPFLQKTLEIFLKEHYPIAKVLRTNGRQGLIRTRVLGAKEAIGDVLIFLDSHSEANVNWLPPLLEPIAKNYKTVTCPFIDVINYDTFEYLSQDEGARGIFDWNFDYKRIPRFKSDESHPADPFESPVMAGGLFAISRKWFWELGGYDEGLDIWGGEQYEISFKLWQCGGKMLDVPCSRIGHVYRKYSPFPNNAKGNFISRNFKRVAEVWMDEFKEYLYLRR-PTIRNEDPLNLTNQFAIREKLHCKNFSWFMKEVAFDLVNNYPLIEPNPVCSGEIKLSNPNNVSVCIDFKFRDSGYVVGLSPCLSVNHKE-GGEQNFILSWKGEIKPKDRDMCMDSSDHIPGGSVLLFKCHGGRGNQFFKYKLESQQILFVNSGFCLEGDPASKHIALQTCNETITDQKWIWTSVN 589