Inositol 1,4,5-trisphosphate receptor type 3

Overview
NameInositol 1,4,5-trisphosphate receptor type 3
Smed IDSMED30018386
Length (bp)8298
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Inositol 1,4,5-trisphosphate receptor type 3 (SMED30018386) t-SNE clustered cells

Violin plots show distribution of expression levels for Inositol 1,4,5-trisphosphate receptor type 3 (SMED30018386) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Inositol 1,4,5-trisphosphate receptor type 3 (SMED30018386) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Inositol 1,4,5-trisphosphate receptor type 3 (SMED30018386) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30018386

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 8

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
parapharyngeal regionSMED30018386h1SMcG0000382 SmedASXL_019883SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016
whole organism asexual adult RNA-sequencing evidence
pharynxSMED30018386h1SMcG0000382 dd_Smed_v4_14214_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
protonephridiaSMED30018386h1SMcG0000382 dd_Smed_v4_14214_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
nervous systemSMED30018386h1SMcG0000382 dd_Smed_v4_14214_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30018386h1SMcG0000382 dd_Smed_v4_14214_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
muscle cellSMED30018386h1SMcG0000382 dd_Smed_v4_14214_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30018386h1SMcG0000382 dd_Smed_v4_14214_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cilated neuronSMED30018386h1SMcG0000382 dd_Smed_v4_14214_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of Inositol 1,4,5-trisphosphate receptor type 3 vs. Ensembl Human
Match: ITPR2 (inositol 1,4,5-trisphosphate receptor type 2 [Source:HGNC Symbol;Acc:HGNC:6181])

HSP 1 Score: 117.087 bits (292), Expect = 4.868e-25
Identity = 171/708 (24.15%), Postives = 298/708 (42.09%), Query Frame = 2
Query:  164 MNDYLSYGDRICLYCEET-NGFINS-----NNSSSHYNELRIFSKQDKFNPENVSDIQEIIFEVVIQNRXXXXXXX-XXXXXDINNKSENLELKIQAEQAKATVISEENDNALENRRNLGKTVHYGDVIQLRHVYTRKYIHVNIAKTSSKDQNSMILNLQSHNLKSAQFKIVPRYKVKYEGEPVQFMDLVTFESLKAPSHYFHASDLYQIDNFFHGA----ALNLATEQSGFTLIKSASDTHIMEEDNFLRGGDYIQIIHKEIDGYIESEGIQGGMKKADIYLRIRKSDKFQTLTNSRLSS-SANTFWQVEI---EKVRLSTEIGQWSSNFRFRHATNRLYLSVK---------------KDLSVSMTK--------------NATNPNTVFRLYPQNIDKL-----IIPYGRYFRMEHVLTGTWIHANKEQVYVKPNQSKYDDAAEKCLGNLKYETNELRELFCVHQRLYDDAFVVFKVPTEIVESFNLLSGYFPLIKNLIVDRKKAVPFTASQSYRYKLALEEIRDSLY------------LD---GKPHSLRQKHLRNLQIVDLLVELVLLPFHSKIDAAFTEKI----------YRASFEILHNYMKGSS---IKNSLYFAKYINLFEPKMLENNDLGHKII--EMIAELLRNNQKVLE-CISFQEIFPFIDNLRINQNFRYLEYLETFCVCNGE--PMTQNQI 2041
            M+ +L  GD + LY E + NGFI++     +    H     + +   KF        ++ +F+V   NRY   K+Y         N +E   LK     A+     E+  N  EN++ LG+ V Y +VIQL H+ + KY+ VN    +  ++N+M ++L +   + + F I P +K++ EG+ +   D V    + A     HAS++  +DN   G     A+N  T       +K +S       ++ L+GGD +++ H E + ++  +  +   KK  I+LR        TL  S  S+ S+   W++E+   +  R     GQW+S FRF+H     YL+ +               +D     +K              +  + N +  L+  +   L     ++P   Y R+ H+ T TW+ +    +          D  E+    LK  T + +E          +AF +  VP   V   +  +    ++   +   KK    T +Q+ R +   + + D ++            LD    KP+  RQK +R   I+  +  ++  PF  K       ++          Y+    + +  ++ S     KN  Y AK   + + +      +G+ I+  + I  LL NN+K+LE  I+ +EI  F+  LR N+  R+L+YL   CV N    P+TQ  I
Sbjct:    5 MSSFLYIGDIVSLYAEGSVNGFISTLGLVDDRCVVHPEAGDLANPPKKF--------RDCLFKVCPMNRYSAQKQYWKAKQAKQGNHTEAALLKKLQHAAEL----EQKQNESENKKLLGEIVKYSNVIQLLHIKSNKYLTVNKRLPALLEKNAMRVSLDAAGNEGSWFYIHPFWKLRSEGDNIVVGDKVVLMPVNA-GQPLHASNIELLDN--PGCKEVNAVNCNTSWKITLFMKYSS-----YREDVLKGGDVVRLFHAEQEKFLTCDEYE---KKQHIFLRT-------TLRQSATSATSSKALWEIEVVHHDPCRGGA--GQWNSLFRFKHLATGNYLAAELNPDYRDAQNEGKNVRDGVPPTSKKKRQAGEKIMYTLVSVPHGNDIASLFELDATTLQRADCLVPRNSYVRLRHLCTNTWVTSTSIPI----------DTDEERPVMLKIGTCQTKE--------DKEAFAIVSVPLSEVRDLDFANDANKVLATTV---KKLENGTITQNER-RFVTKLLEDLIFFVADVPNNGQEVLDVVITKPNRERQKLMREQNILAQVFGILKAPFKEKAGEGSMLRLEDLGDQRYAPYKYMLRLCYRVLRHSQQDYRKNQEYIAKNFCVMQSQ------IGYDILAEDTITALLHNNRKLLEKHITAKEIETFVSLLRRNREPRFLDYLSDLCVSNTTAIPVTQELI 652          

HSP 2 Score: 83.5741 bits (205), Expect = 6.943e-15
Identity = 40/98 (40.82%), Postives = 59/98 (60.20%), Query Frame = 3
Query: 7584 VDTFSELRDLKYKTEKDMKETCFICSRAGHDFDQSSSSFEHHVVYEHNMWAYLFYFLHLKEIKINDYFHLDLYVANMLKRENYDFFPINCALSLTAEQ 7877
            +DTF++LR  K K E+ +K TCFIC      FD  + SFE H+  EHNMW YL++ + +K     +Y   + YVA M+  +N D+FP   A+SL + +
Sbjct: 2541 IDTFADLRSEKQKKEEILKTTCFICGLERDKFDNKTVSFEEHIKSEHNMWHYLYFIVLVKVKDPTEYTGPESYVAQMIVEKNLDWFPRMRAMSLVSNE 2638          
BLAST of Inositol 1,4,5-trisphosphate receptor type 3 vs. Ensembl Human
Match: ITPR1 (inositol 1,4,5-trisphosphate receptor type 1 [Source:HGNC Symbol;Acc:HGNC:6180])

HSP 1 Score: 107.842 bits (268), Expect = 2.850e-22
Identity = 107/412 (25.97%), Postives = 186/412 (45.15%), Query Frame = 2
Query:  164 MNDYLSYGDRICLYCE-ETNGFINSNNSSSHYNELRIFSKQDKFNPEN------VSDIQEIIFEVVIQNRXXXXXXXXXXXXDINNKSENLELKIQAEQAKATVISEENDNALENRRNLGKTVHYGDVIQLRHVYTRKYIHVNIAKTSSKDQNSMILNLQSHNLKSAQFKIVPRYKVKYEGEPVQFMDLVTFESLKAPSHYFHASDLYQIDNFFHGA----ALNLATEQSGFTLIKSASDTHIMEEDNFLRGGDYIQIIHKEIDGYIESEGIQGGMKKADIYLRIRKSDKFQTLTNSRLSSSANTFWQVE-IEKVRLSTEIGQWSSNFRFRHATNRLYLSVK----KDLSVSMTKNA--------------TNPNTVFRLYPQNI--DKLIIPYGRYFRMEHVLTGTWIHAN 1303
            M+ +L  GD   LY E  TNGFI++         L +   +    PE           ++ +F++   NRY   K++ K  K   N + +  L  +   A      E+  N  ENR+ LG  + YG+VIQL H+ + KY+ VN    +  ++N+M + L     + + F I P YK++  G+ V   D V    + A     HAS    +DN   G     ++N  T       +K + +     +D+ L+GGD +++ H E + ++  +  +   KK  ++LR   +   Q+ T+   ++S+   W+VE ++        G W+S FRF+H     YL+ +    +D S S  +NA               + +++F L P  +     ++P   Y R+ H+ T TW+H+ 
Sbjct:    5 MSSFLHIGDICSLYAEGSTNGFIST---------LGLVDDRCVVQPETGDLNNPPKKFRDCLFKLCPMNRYSAQKQFWKAAKPGANSTTDAVLLNKLHHAADL---EKKQNETENRKLLGTVIQYGNVIQLLHLKSNKYLTVNKRLPALLEKNAMRVTLDEAGNEGSWFYIQPFYKLRSIGDSVVIGDKVVLNPVNA-GQPLHASSHQLVDN--PGCNEVNSVNCNTSWKIVLFMKWSDN-----KDDILKGGDVVRLFHAEQEKFLTCDEHR---KKQHVFLR---TTGRQSATS---ATSSKALWEVEVVQHDPCRGGAGYWNSLFRFKHLATGHYLAAEVDPDQDASRSRLRNAQEKMVYSLVSVPEGNDISSIFELDPTTLRGGDSLVPRNSYVRLRHLCTNTWVHST 387          

HSP 2 Score: 83.5741 bits (205), Expect = 6.329e-15
Identity = 49/147 (33.33%), Postives = 75/147 (51.02%), Query Frame = 3
Query: 7584 VDTFSELRDLKYKTEKDMKETCFICSRAGHDFDQSSSSFEHHVVYEHNMWAYLFYFLHLKEIKINDYFHLDLYVANMLKRENYDFFPINCALSLT-----AEQEKYSRIDEISRNVKIIVSN----------RQNEEREKLRRTNLF 7979
            +DTF++LR  K K E+ +K TCFIC      FD  + +FE H+  EHNMW YL + + +K     +Y   + YVA M+K  N D+FP   A+SL       EQ +   + E   +   +V+N          +  E+R++ +R  L 
Sbjct: 2535 IDTFADLRSEKQKKEEILKTTCFICGLERDKFDNKTVTFEEHIKEEHNMWHYLCFIVLVKVKDSTEYTGPESYVAEMIKERNLDWFPRMRAMSLVSSDSEGEQNELRNLQEKLESTMKLVTNLSGQLSELKDQMTEQRKQKQRIGLL 2681          
BLAST of Inositol 1,4,5-trisphosphate receptor type 3 vs. Ensembl Human
Match: ITPR1 (inositol 1,4,5-trisphosphate receptor type 1 [Source:HGNC Symbol;Acc:HGNC:6180])

HSP 1 Score: 107.842 bits (268), Expect = 2.959e-22
Identity = 107/411 (26.03%), Postives = 186/411 (45.26%), Query Frame = 2
Query:  164 MNDYLSYGDRICLYCE-ETNGFINSNNSSSHYNELRIFSKQDKFNPEN------VSDIQEIIFEVVIQNRXXXXXXXXXXXXDINNKSENLELKIQAEQAKATVISEENDNALENRRNLGKTVHYGDVIQLRHVYTRKYIHVNIAKTSSKDQNSMILNLQSHNLKSAQFKIVPRYKVKYEGEPVQFMDLVTFESLKAPSHYFHASDLYQIDNFFHGA----ALNLATEQSGFTLIKSASDTHIMEEDNFLRGGDYIQIIHKEIDGYIESEGIQGGMKKADIYLRIRKSDKFQTLTNSRLSSSANTFWQVE-IEKVRLSTEIGQWSSNFRFRHATNRLYLSVK----KDLSVSMTKNA--------------TNPNTVFRLYPQNI--DKLIIPYGRYFRMEHVLTGTWIHA 1300
            M+ +L  GD   LY E  TNGFI++         L +   +    PE           ++ +F++   NRY   K++ K  K   N + +  L  +   A      E+  N  ENR+ LG  + YG+VIQL H+ + KY+ VN    +  ++N+M + L     + + F I P YK++  G+ V   D V    + A     HAS    +DN   G     ++N  T       +K + +     +D+ L+GGD +++ H E + ++  +  +   KK  ++LR   +   Q+ T+   ++S+   W+VE ++        G W+S FRF+H     YL+ +    +D S S  +NA               + +++F L P  +     ++P   Y R+ H+ T TW+H+
Sbjct:    5 MSSFLHIGDICSLYAEGSTNGFIST---------LGLVDDRCVVQPETGDLNNPPKKFRDCLFKLCPMNRYSAQKQFWKAAKPGANSTTDAVLLNKLHHAADL---EKKQNETENRKLLGTVIQYGNVIQLLHLKSNKYLTVNKRLPALLEKNAMRVTLDEAGNEGSWFYIQPFYKLRSIGDSVVIGDKVVLNPVNA-GQPLHASSHQLVDN--PGCNEVNSVNCNTSWKIVLFMKWSDN-----KDDILKGGDVVRLFHAEQEKFLTCDEHR---KKQHVFLR---TTGRQSATS---ATSSKALWEVEVVQHDPCRGGAGYWNSLFRFKHLATGHYLAAEVDPDQDASRSRLRNAQEKMVYSLVSVPEGNDISSIFELDPTTLRGGDSLVPRNSYVRLRHLCTNTWVHS 386          

HSP 2 Score: 83.5741 bits (205), Expect = 6.240e-15
Identity = 49/147 (33.33%), Postives = 75/147 (51.02%), Query Frame = 3
Query: 7584 VDTFSELRDLKYKTEKDMKETCFICSRAGHDFDQSSSSFEHHVVYEHNMWAYLFYFLHLKEIKINDYFHLDLYVANMLKRENYDFFPINCALSLT-----AEQEKYSRIDEISRNVKIIVSN----------RQNEEREKLRRTNLF 7979
            +DTF++LR  K K E+ +K TCFIC      FD  + +FE H+  EHNMW YL + + +K     +Y   + YVA M+K  N D+FP   A+SL       EQ +   + E   +   +V+N          +  E+R++ +R  L 
Sbjct: 2583 IDTFADLRSEKQKKEEILKTTCFICGLERDKFDNKTVTFEEHIKEEHNMWHYLCFIVLVKVKDSTEYTGPESYVAEMIKERNLDWFPRMRAMSLVSSDSEGEQNELRNLQEKLESTMKLVTNLSGQLSELKDQMTEQRKQKQRIGLL 2729          
BLAST of Inositol 1,4,5-trisphosphate receptor type 3 vs. Ensembl Human
Match: ITPR1 (inositol 1,4,5-trisphosphate receptor type 1 [Source:HGNC Symbol;Acc:HGNC:6180])

HSP 1 Score: 107.842 bits (268), Expect = 2.959e-22
Identity = 107/411 (26.03%), Postives = 186/411 (45.26%), Query Frame = 2
Query:  164 MNDYLSYGDRICLYCE-ETNGFINSNNSSSHYNELRIFSKQDKFNPEN------VSDIQEIIFEVVIQNRXXXXXXXXXXXXDINNKSENLELKIQAEQAKATVISEENDNALENRRNLGKTVHYGDVIQLRHVYTRKYIHVNIAKTSSKDQNSMILNLQSHNLKSAQFKIVPRYKVKYEGEPVQFMDLVTFESLKAPSHYFHASDLYQIDNFFHGA----ALNLATEQSGFTLIKSASDTHIMEEDNFLRGGDYIQIIHKEIDGYIESEGIQGGMKKADIYLRIRKSDKFQTLTNSRLSSSANTFWQVE-IEKVRLSTEIGQWSSNFRFRHATNRLYLSVK----KDLSVSMTKNA--------------TNPNTVFRLYPQNI--DKLIIPYGRYFRMEHVLTGTWIHA 1300
            M+ +L  GD   LY E  TNGFI++         L +   +    PE           ++ +F++   NRY   K++ K  K   N + +  L  +   A      E+  N  ENR+ LG  + YG+VIQL H+ + KY+ VN    +  ++N+M + L     + + F I P YK++  G+ V   D V    + A     HAS    +DN   G     ++N  T       +K + +     +D+ L+GGD +++ H E + ++  +  +   KK  ++LR   +   Q+ T+   ++S+   W+VE ++        G W+S FRF+H     YL+ +    +D S S  +NA               + +++F L P  +     ++P   Y R+ H+ T TW+H+
Sbjct:    5 MSSFLHIGDICSLYAEGSTNGFIST---------LGLVDDRCVVQPETGDLNNPPKKFRDCLFKLCPMNRYSAQKQFWKAAKPGANSTTDAVLLNKLHHAADL---EKKQNETENRKLLGTVIQYGNVIQLLHLKSNKYLTVNKRLPALLEKNAMRVTLDEAGNEGSWFYIQPFYKLRSIGDSVVIGDKVVLNPVNA-GQPLHASSHQLVDN--PGCNEVNSVNCNTSWKIVLFMKWSDN-----KDDILKGGDVVRLFHAEQEKFLTCDEHR---KKQHVFLR---TTGRQSATS---ATSSKALWEVEVVQHDPCRGGAGYWNSLFRFKHLATGHYLAAEVDPDQDASRSRLRNAQEKMVYSLVSVPEGNDISSIFELDPTTLRGGDSLVPRNSYVRLRHLCTNTWVHS 386          

HSP 2 Score: 83.5741 bits (205), Expect = 6.240e-15
Identity = 49/147 (33.33%), Postives = 75/147 (51.02%), Query Frame = 3
Query: 7584 VDTFSELRDLKYKTEKDMKETCFICSRAGHDFDQSSSSFEHHVVYEHNMWAYLFYFLHLKEIKINDYFHLDLYVANMLKRENYDFFPINCALSLT-----AEQEKYSRIDEISRNVKIIVSN----------RQNEEREKLRRTNLF 7979
            +DTF++LR  K K E+ +K TCFIC      FD  + +FE H+  EHNMW YL + + +K     +Y   + YVA M+K  N D+FP   A+SL       EQ +   + E   +   +V+N          +  E+R++ +R  L 
Sbjct: 2583 IDTFADLRSEKQKKEEILKTTCFICGLERDKFDNKTVTFEEHIKEEHNMWHYLCFIVLVKVKDSTEYTGPESYVAEMIKERNLDWFPRMRAMSLVSSDSEGEQNELRNLQEKLESTMKLVTNLSGQLSELKDQMTEQRKQKQRIGLL 2729          
BLAST of Inositol 1,4,5-trisphosphate receptor type 3 vs. Ensembl Human
Match: ITPR1 (inositol 1,4,5-trisphosphate receptor type 1 [Source:HGNC Symbol;Acc:HGNC:6180])

HSP 1 Score: 107.842 bits (268), Expect = 2.959e-22
Identity = 107/411 (26.03%), Postives = 186/411 (45.26%), Query Frame = 2
Query:  164 MNDYLSYGDRICLYCE-ETNGFINSNNSSSHYNELRIFSKQDKFNPEN------VSDIQEIIFEVVIQNRXXXXXXXXXXXXDINNKSENLELKIQAEQAKATVISEENDNALENRRNLGKTVHYGDVIQLRHVYTRKYIHVNIAKTSSKDQNSMILNLQSHNLKSAQFKIVPRYKVKYEGEPVQFMDLVTFESLKAPSHYFHASDLYQIDNFFHGA----ALNLATEQSGFTLIKSASDTHIMEEDNFLRGGDYIQIIHKEIDGYIESEGIQGGMKKADIYLRIRKSDKFQTLTNSRLSSSANTFWQVE-IEKVRLSTEIGQWSSNFRFRHATNRLYLSVK----KDLSVSMTKNA--------------TNPNTVFRLYPQNI--DKLIIPYGRYFRMEHVLTGTWIHA 1300
            M+ +L  GD   LY E  TNGFI++         L +   +    PE           ++ +F++   NRY   K++ K  K   N + +  L  +   A      E+  N  ENR+ LG  + YG+VIQL H+ + KY+ VN    +  ++N+M + L     + + F I P YK++  G+ V   D V    + A     HAS    +DN   G     ++N  T       +K + +     +D+ L+GGD +++ H E + ++  +  +   KK  ++LR   +   Q+ T+   ++S+   W+VE ++        G W+S FRF+H     YL+ +    +D S S  +NA               + +++F L P  +     ++P   Y R+ H+ T TW+H+
Sbjct:    5 MSSFLHIGDICSLYAEGSTNGFIST---------LGLVDDRCVVQPETGDLNNPPKKFRDCLFKLCPMNRYSAQKQFWKAAKPGANSTTDAVLLNKLHHAADL---EKKQNETENRKLLGTVIQYGNVIQLLHLKSNKYLTVNKRLPALLEKNAMRVTLDEAGNEGSWFYIQPFYKLRSIGDSVVIGDKVVLNPVNA-GQPLHASSHQLVDN--PGCNEVNSVNCNTSWKIVLFMKWSDN-----KDDILKGGDVVRLFHAEQEKFLTCDEHR---KKQHVFLR---TTGRQSATS---ATSSKALWEVEVVQHDPCRGGAGYWNSLFRFKHLATGHYLAAEVDPDQDASRSRLRNAQEKMVYSLVSVPEGNDISSIFELDPTTLRGGDSLVPRNSYVRLRHLCTNTWVHS 386          

HSP 2 Score: 83.5741 bits (205), Expect = 6.241e-15
Identity = 49/147 (33.33%), Postives = 75/147 (51.02%), Query Frame = 3
Query: 7584 VDTFSELRDLKYKTEKDMKETCFICSRAGHDFDQSSSSFEHHVVYEHNMWAYLFYFLHLKEIKINDYFHLDLYVANMLKRENYDFFPINCALSLT-----AEQEKYSRIDEISRNVKIIVSN----------RQNEEREKLRRTNLF 7979
            +DTF++LR  K K E+ +K TCFIC      FD  + +FE H+  EHNMW YL + + +K     +Y   + YVA M+K  N D+FP   A+SL       EQ +   + E   +   +V+N          +  E+R++ +R  L 
Sbjct: 2584 IDTFADLRSEKQKKEEILKTTCFICGLERDKFDNKTVTFEEHIKEEHNMWHYLCFIVLVKVKDSTEYTGPESYVAEMIKERNLDWFPRMRAMSLVSSDSEGEQNELRNLQEKLESTMKLVTNLSGQLSELKDQMTEQRKQKQRIGLL 2730          
BLAST of Inositol 1,4,5-trisphosphate receptor type 3 vs. Ensembl Celegans
Match: itr-1 (Inositol 1,4,5-trisphosphate receptor itr-1 [Source:UniProtKB/Swiss-Prot;Acc:Q9Y0A1])

HSP 1 Score: 93.2041 bits (230), Expect = 2.473e-18
Identity = 147/716 (20.53%), Postives = 274/716 (38.27%), Query Frame = 2
Query:  443 KATVISEENDNALENRRNLGKTVHYGDVIQLRHVYTRKYIHVNIAKTSSKDQNSMILNLQSHNLKSAQFKIVPRYKVKYEGEPVQFMDLVTFESLKAPSHYFHASDLYQIDNFFHGAALNLATEQSG--FTLIKSASDTHIM-------EEDNFLRGGDYIQIIHKEIDGYIESEGIQGGMKKAD-IYLRIRKSDKFQTLTNSRLSSSANTFWQVEIEKVRL-STEIGQWSSNFRFRHATNRLYLSV--------------KKDLSVSMTKN-----ATNPNTV---------------------------------FRLYPQNIDKL--IIPYGRYFRMEHVLTGTWIHANKEQVYVKPNQSKYDDAAEKCLGNLKYETNELR---ELFCVHQRLYDDAFVVFKV-PTEIV------ESFNLLSGYFPLIKNLIVDRKKAVPFTASQSYRYKL----ALEEIRDSLYL-DGKPHSLRQKHLRNLQIVDLLVELVLLPFHSKIDAAFTE----------------KIYRASFEILHNYMKGSSI---KNSLYFAKYINLFEPKMLENNDLGHKII--EMIAELLRNNQKVLE-CISFQEIFPFIDNLRINQNFRYLEYLETFCVCNGEPMTQNQIKIAVKWLSEDQRGVFLTDRGQNLNLESNVIYIKTKLDSNWMK-LHEFLDITAQIDQENNPLYHQDNKDYFLKQMDLLLALC 2281
            K     E  +N  E ++ LG  + YG ++QL HV + KYI V     + +++N+M + L     + + F I P YK    G+ V   + ++      P+     +    + +  H ++ NL   QS      +   ++  +         + N ++ GD +++ H +   ++  + I       D ++LR+         T+SR        W+V++ +         +W+  +RF+H    +YLS               +  L  S T N     +  PN V                                 F+L P    K    +P   Y R+ H  +  W+HA               +A EK   NL Y +   +   ++ C   R+  + F +  V P E+       ++   L  +  LIK   V  K+++  T        L    + + + D L + D  P   RQK LR  ++++ +  L+  PF  +     TE                +I++  F++ +  +K S +   KN  + A+     + +      +G  ++  + +  +L NN K+LE  +    +  F++ +R N+  ++L+YL   CVC GE   + Q  I    LS   R +F+  +            I  +++  W     + +DI       ++   H    DY+  Q+DLL  +C
Sbjct:  127 KVAADKEREENESEFQKTLGNVIQYGSMVQLLHVKSNKYITVQKNSPAKRERNAMKVYLDRAGNEGSWFIIEPAYKHYAIGDNVSAGNKISL----IPNS-VSTTQAGHVKSQLHLSSFNLLDHQSAAEVNCLNEPTEWQVFMFLLFDENQQNSVKSGDVVRLFHADQQTFLTLDTIPKQNPPTDVVFLRMTNRPSAADATSSR------ALWEVQVVQTNAYRGGTAKWNKAYRFKHLATDMYLSAEPSQVQVKPAMNGRRASLIYSKTNNPMAMYSDGPNGVTNESTDTTQQNIPSVWVLGPTKSEFPEEDANLLFQLDPSTFMKSNKEVPRRSYVRLLHQSSDKWVHAT--------------NATEK--QNLHYSSKNEKGWVKVICEKNRVDKETFALLPVNPDEVRDLDFANDACKALRNFIKLIKIGQVISKESINSTTQLLIDCILFVTNSSDHLADPLKISDFSPSRDRQKLLREQEVLNQVFLLLKAPFLPR--QGTTELGPLLSSPSELSDSRNEIFKTMFQLCYCLLKYSQVSYRKNQEFLAEKFGEIQEQ------IGFDLMAEDTMTAVLHNNPKLLEKYVKTPHVERFVELVRNNRQGKFLDYLADLCVCRGEANKKIQELICTSVLSSKHRDIFMDTK-----------IIDGEIEVGWAPNFRKLVDIAEGAKSNSDDAEHL---DYYRHQLDLLSQMC 793          
BLAST of Inositol 1,4,5-trisphosphate receptor type 3 vs. Ensembl Celegans
Match: itr-1 (Inositol 1,4,5-trisphosphate receptor itr-1 [Source:UniProtKB/Swiss-Prot;Acc:Q9Y0A1])

HSP 1 Score: 93.5893 bits (231), Expect = 2.718e-18
Identity = 147/716 (20.53%), Postives = 274/716 (38.27%), Query Frame = 2
Query:  443 KATVISEENDNALENRRNLGKTVHYGDVIQLRHVYTRKYIHVNIAKTSSKDQNSMILNLQSHNLKSAQFKIVPRYKVKYEGEPVQFMDLVTFESLKAPSHYFHASDLYQIDNFFHGAALNLATEQSG--FTLIKSASDTHIM-------EEDNFLRGGDYIQIIHKEIDGYIESEGIQGGMKKAD-IYLRIRKSDKFQTLTNSRLSSSANTFWQVEIEKVRL-STEIGQWSSNFRFRHATNRLYLSV--------------KKDLSVSMTKN-----ATNPNTV---------------------------------FRLYPQNIDKL--IIPYGRYFRMEHVLTGTWIHANKEQVYVKPNQSKYDDAAEKCLGNLKYETNELR---ELFCVHQRLYDDAFVVFKV-PTEIV------ESFNLLSGYFPLIKNLIVDRKKAVPFTASQSYRYKL----ALEEIRDSLYL-DGKPHSLRQKHLRNLQIVDLLVELVLLPFHSKIDAAFTE----------------KIYRASFEILHNYMKGSSI---KNSLYFAKYINLFEPKMLENNDLGHKII--EMIAELLRNNQKVLE-CISFQEIFPFIDNLRINQNFRYLEYLETFCVCNGEPMTQNQIKIAVKWLSEDQRGVFLTDRGQNLNLESNVIYIKTKLDSNWMK-LHEFLDITAQIDQENNPLYHQDNKDYFLKQMDLLLALC 2281
            K     E  +N  E ++ LG  + YG ++QL HV + KYI V     + +++N+M + L     + + F I P YK    G+ V   + ++      P+     +    + +  H ++ NL   QS      +   ++  +         + N ++ GD +++ H +   ++  + I       D ++LR+         T+SR        W+V++ +         +W+  +RF+H    +YLS               +  L  S T N     +  PN V                                 F+L P    K    +P   Y R+ H  +  W+HA               +A EK   NL Y +   +   ++ C   R+  + F +  V P E+       ++   L  +  LIK   V  K+++  T        L    + + + D L + D  P   RQK LR  ++++ +  L+  PF  +     TE                +I++  F++ +  +K S +   KN  + A+     + +      +G  ++  + +  +L NN K+LE  +    +  F++ +R N+  ++L+YL   CVC GE   + Q  I    LS   R +F+  +            I  +++  W     + +DI       ++   H    DY+  Q+DLL  +C
Sbjct:  173 KVAADKEREENESEFQKTLGNVIQYGSMVQLLHVKSNKYITVQKNSPAKRERNAMKVYLDRAGNEGSWFIIEPAYKHYAIGDNVSAGNKISL----IPNS-VSTTQAGHVKSQLHLSSFNLLDHQSAAEVNCLNEPTEWQVFMFLLFDENQQNSVKSGDVVRLFHADQQTFLTLDTIPKQNPPTDVVFLRMTNRPSAADATSSR------ALWEVQVVQTNAYRGGTAKWNKAYRFKHLATDMYLSAEPSQVQVKPAMNGRRASLIYSKTNNPMAMYSDGPNGVTNESTDTTQQNIPSVWVLGPTKSEFPEEDANLLFQLDPSTFMKSNKEVPRRSYVRLLHQSSDKWVHAT--------------NATEK--QNLHYSSKNEKGWVKVICEKNRVDKETFALLPVNPDEVRDLDFANDACKALRNFIKLIKIGQVISKESINSTTQLLIDCILFVTNSSDHLADPLKISDFSPSRDRQKLLREQEVLNQVFLLLKAPFLPR--QGTTELGPLLSSPSELSDSRNEIFKTMFQLCYCLLKYSQVSYRKNQEFLAEKFGEIQEQ------IGFDLMAEDTMTAVLHNNPKLLEKYVKTPHVERFVELVRNNRQGKFLDYLADLCVCRGEANKKIQELICTSVLSSKHRDIFMDTK-----------IIDGEIEVGWAPNFRKLVDIAEGAKSNSDDAEHL---DYYRHQLDLLSQMC 839          

HSP 2 Score: 72.4034 bits (176), Expect = 6.708e-12
Identity = 38/94 (40.43%), Postives = 53/94 (56.38%), Query Frame = 3
Query: 7584 VDTFSELRDLKYKTEKDMKETCFICSRAGHDFDQSSSSFEHHVVYEHNMWAYLFYFLHLKEIKINDYFHLDLYVANMLKRENYDFFPINCALSL 7865
            +DTF +LR  K + E+ +K  CFIC      FD  S +FE H   EHN+W YL+Y + L+     ++   + YVA  +K  N D+FP   ALSL
Sbjct: 2753 IDTFGDLRAEKNEKEQILKNNCFICGLDRSRFDNRSVTFETHRETEHNIWHYLYYIVMLQIKDETEFTGPESYVAQCVKDRNLDWFPRMQALSL 2846          
BLAST of Inositol 1,4,5-trisphosphate receptor type 3 vs. Ensembl Celegans
Match: itr-1 (Inositol 1,4,5-trisphosphate receptor itr-1 [Source:UniProtKB/Swiss-Prot;Acc:Q9Y0A1])

HSP 1 Score: 93.2041 bits (230), Expect = 2.947e-18
Identity = 146/716 (20.39%), Postives = 273/716 (38.13%), Query Frame = 2
Query:  443 KATVISEENDNALENRRNLGKTVHYGDVIQLRHVYTRKYIHVNIAKTSSKDQNSMILNLQSHNLKSAQFKIVPRYKVKYEGEPVQFMDLVTFESLKAPSHYFHASDLYQIDNFFHGAALNLATEQSG--FTLIKSASDTHIM-------EEDNFLRGGDYIQIIHKEIDGYIESEGIQGGMKKAD-IYLRIRKSDKFQTLTNSRLSSSANTFWQVEIEKVRL-STEIGQWSSNFRFRHATNRLYLSV--------------KKDLSVSMTKN-----ATNPNTV---------------------------------FRLYPQNIDKL--IIPYGRYFRMEHVLTGTWIHANKEQVYVKPNQSKYDDAAEKCLGNLKYETNELR---ELFCVHQRLYDDAFVVFKV-PTEIV------ESFNLLSGYFPLIKNLIVDRKKAVPFTASQSYRYKL----ALEEIRDSLYL-DGKPHSLRQKHLRNLQIVDLLVELVLLPFHSKIDAAFTE----------------KIYRASFEILHNYMKGSSI---KNSLYFAKYINLFEPKMLENNDLGHKII--EMIAELLRNNQKVLE-CISFQEIFPFIDNLRINQNFRYLEYLETFCVCNGEPMTQNQIKIAVKWLSEDQRGVFLTDRGQNLNLESNVIYIKTKLDSNWMK-LHEFLDITAQIDQENNPLYHQDNKDYFLKQMDLLLALC 2281
            K     E  +N  E ++ LG  + YG ++QL HV + KYI V     + +++N+M + L     + + F I P YK    G+ V   + ++        +    +    + +  H ++ NL   QS      +   ++  +         + N ++ GD +++ H +   ++  + I       D ++LR+         T+SR        W+V++ +         +W+  +RF+H    +YLS               +  L  S T N     +  PN V                                 F+L P    K    +P   Y R+ H  +  W+HA               +A EK   NL Y +   +   ++ C   R+  + F +  V P E+       ++   L  +  LIK   V  K+++  T        L    + + + D L + D  P   RQK LR  ++++ +  L+  PF  +     TE                +I++  F++ +  +K S +   KN  + A+     + +      +G  ++  + +  +L NN K+LE  +    +  F++ +R N+  ++L+YL   CVC GE   + Q  I    LS   R +F+  +            I  +++  W     + +DI       ++   H    DY+  Q+DLL  +C
Sbjct:  117 KVAADKEREENESEFQKTLGNVIQYGSMVQLLHVKSNKYITVQKNSPAKRERNAMKVYLDRAGNEGSWFIIEPAYKHYAIGDNVSAGNKISL-----IPNSVSTTQAGHVKSQLHLSSFNLLDHQSAAEVNCLNEPTEWQVFMFLLFDENQQNSVKSGDVVRLFHADQQTFLTLDTIPKQNPPTDVVFLRMTNRPSAADATSSR------ALWEVQVVQTNAYRGGTAKWNKAYRFKHLATDMYLSAEPSQVQVKPAMNGRRASLIYSKTNNPMAMYSDGPNGVTNESTDTTQQNIPSVWVLGPTKSEFPEEDANLLFQLDPSTFMKSNKEVPRRSYVRLLHQSSDKWVHAT--------------NATEK--QNLHYSSKNEKGWVKVICEKNRVDKETFALLPVNPDEVRDLDFANDACKALRNFIKLIKIGQVISKESINSTTQLLIDCILFVTNSSDHLADPLKISDFSPSRDRQKLLREQEVLNQVFLLLKAPFLPR--QGTTELGPLLSSPSELSDSRNEIFKTMFQLCYCLLKYSQVSYRKNQEFLAEKFGEIQEQ------IGFDLMAEDTMTAVLHNNPKLLEKYVKTPHVERFVELVRNNRQGKFLDYLADLCVCRGEANKKIQELICTSVLSSKHRDIFMDTK-----------IIDGEIEVGWAPNFRKLVDIAEGAKSNSDDAEHL---DYYRHQLDLLSQMC 783          

HSP 2 Score: 72.4034 bits (176), Expect = 6.581e-12
Identity = 38/94 (40.43%), Postives = 53/94 (56.38%), Query Frame = 3
Query: 7584 VDTFSELRDLKYKTEKDMKETCFICSRAGHDFDQSSSSFEHHVVYEHNMWAYLFYFLHLKEIKINDYFHLDLYVANMLKRENYDFFPINCALSL 7865
            +DTF +LR  K + E+ +K  CFIC      FD  S +FE H   EHN+W YL+Y + L+     ++   + YVA  +K  N D+FP   ALSL
Sbjct: 2697 IDTFGDLRAEKNEKEQILKNNCFICGLDRSRFDNRSVTFETHRETEHNIWHYLYYIVMLQIKDETEFTGPESYVAQCVKDRNLDWFPRMQALSL 2790          
BLAST of Inositol 1,4,5-trisphosphate receptor type 3 vs. Ensembl Celegans
Match: itr-1 (Inositol 1,4,5-trisphosphate receptor itr-1 [Source:UniProtKB/Swiss-Prot;Acc:Q9Y0A1])

HSP 1 Score: 93.2041 bits (230), Expect = 3.320e-18
Identity = 147/716 (20.53%), Postives = 274/716 (38.27%), Query Frame = 2
Query:  443 KATVISEENDNALENRRNLGKTVHYGDVIQLRHVYTRKYIHVNIAKTSSKDQNSMILNLQSHNLKSAQFKIVPRYKVKYEGEPVQFMDLVTFESLKAPSHYFHASDLYQIDNFFHGAALNLATEQSG--FTLIKSASDTHIM-------EEDNFLRGGDYIQIIHKEIDGYIESEGIQGGMKKAD-IYLRIRKSDKFQTLTNSRLSSSANTFWQVEIEKVRL-STEIGQWSSNFRFRHATNRLYLSV--------------KKDLSVSMTKN-----ATNPNTV---------------------------------FRLYPQNIDKL--IIPYGRYFRMEHVLTGTWIHANKEQVYVKPNQSKYDDAAEKCLGNLKYETNELR---ELFCVHQRLYDDAFVVFKV-PTEIV------ESFNLLSGYFPLIKNLIVDRKKAVPFTASQSYRYKL----ALEEIRDSLYL-DGKPHSLRQKHLRNLQIVDLLVELVLLPFHSKIDAAFTE----------------KIYRASFEILHNYMKGSSI---KNSLYFAKYINLFEPKMLENNDLGHKII--EMIAELLRNNQKVLE-CISFQEIFPFIDNLRINQNFRYLEYLETFCVCNGEPMTQNQIKIAVKWLSEDQRGVFLTDRGQNLNLESNVIYIKTKLDSNWMK-LHEFLDITAQIDQENNPLYHQDNKDYFLKQMDLLLALC 2281
            K     E  +N  E ++ LG  + YG ++QL HV + KYI V     + +++N+M + L     + + F I P YK    G+ V   + ++      P+     +    + +  H ++ NL   QS      +   ++  +         + N ++ GD +++ H +   ++  + I       D ++LR+         T+SR        W+V++ +         +W+  +RF+H    +YLS               +  L  S T N     +  PN V                                 F+L P    K    +P   Y R+ H  +  W+HA               +A EK   NL Y +   +   ++ C   R+  + F +  V P E+       ++   L  +  LIK   V  K+++  T        L    + + + D L + D  P   RQK LR  ++++ +  L+  PF  +     TE                +I++  F++ +  +K S +   KN  + A+     + +      +G  ++  + +  +L NN K+LE  +    +  F++ +R N+  ++L+YL   CVC GE   + Q  I    LS   R +F+  +            I  +++  W     + +DI       ++   H    DY+  Q+DLL  +C
Sbjct:  127 KVAADKEREENESEFQKTLGNVIQYGSMVQLLHVKSNKYITVQKNSPAKRERNAMKVYLDRAGNEGSWFIIEPAYKHYAIGDNVSAGNKISL----IPNS-VSTTQAGHVKSQLHLSSFNLLDHQSAAEVNCLNEPTEWQVFMFLLFDENQQNSVKSGDVVRLFHADQQTFLTLDTIPKQNPPTDVVFLRMTNRPSAADATSSR------ALWEVQVVQTNAYRGGTAKWNKAYRFKHLATDMYLSAEPSQVQVKPAMNGRRASLIYSKTNNPMAMYSDGPNGVTNESTDTTQQNIPSVWVLGPTKSEFPEEDANLLFQLDPSTFMKSNKEVPRRSYVRLLHQSSDKWVHAT--------------NATEK--QNLHYSSKNEKGWVKVICEKNRVDKETFALLPVNPDEVRDLDFANDACKALRNFIKLIKIGQVISKESINSTTQLLIDCILFVTNSSDHLADPLKISDFSPSRDRQKLLREQEVLNQVFLLLKAPFLPR--QGTTELGPLLSSPSELSDSRNEIFKTMFQLCYCLLKYSQVSYRKNQEFLAEKFGEIQEQ------IGFDLMAEDTMTAVLHNNPKLLEKYVKTPHVERFVELVRNNRQGKFLDYLADLCVCRGEANKKIQELICTSVLSSKHRDIFMDTK-----------IIDGEIEVGWAPNFRKLVDIAEGAKSNSDDAEHL---DYYRHQLDLLSQMC 793          

HSP 2 Score: 72.4034 bits (176), Expect = 6.815e-12
Identity = 38/94 (40.43%), Postives = 53/94 (56.38%), Query Frame = 3
Query: 7584 VDTFSELRDLKYKTEKDMKETCFICSRAGHDFDQSSSSFEHHVVYEHNMWAYLFYFLHLKEIKINDYFHLDLYVANMLKRENYDFFPINCALSL 7865
            +DTF +LR  K + E+ +K  CFIC      FD  S +FE H   EHN+W YL+Y + L+     ++   + YVA  +K  N D+FP   ALSL
Sbjct: 2728 IDTFGDLRAEKNEKEQILKNNCFICGLDRSRFDNRSVTFETHRETEHNIWHYLYYIVMLQIKDETEFTGPESYVAQCVKDRNLDWFPRMQALSL 2821          
BLAST of Inositol 1,4,5-trisphosphate receptor type 3 vs. Ensembl Celegans
Match: itr-1 (Inositol 1,4,5-trisphosphate receptor itr-1 [Source:UniProtKB/Swiss-Prot;Acc:Q9Y0A1])

HSP 1 Score: 92.8189 bits (229), Expect = 3.729e-18
Identity = 147/716 (20.53%), Postives = 274/716 (38.27%), Query Frame = 2
Query:  443 KATVISEENDNALENRRNLGKTVHYGDVIQLRHVYTRKYIHVNIAKTSSKDQNSMILNLQSHNLKSAQFKIVPRYKVKYEGEPVQFMDLVTFESLKAPSHYFHASDLYQIDNFFHGAALNLATEQSG--FTLIKSASDTHIM-------EEDNFLRGGDYIQIIHKEIDGYIESEGIQGGMKKAD-IYLRIRKSDKFQTLTNSRLSSSANTFWQVEIEKVRL-STEIGQWSSNFRFRHATNRLYLSV--------------KKDLSVSMTKN-----ATNPNTV---------------------------------FRLYPQNIDKL--IIPYGRYFRMEHVLTGTWIHANKEQVYVKPNQSKYDDAAEKCLGNLKYETNELR---ELFCVHQRLYDDAFVVFKV-PTEIV------ESFNLLSGYFPLIKNLIVDRKKAVPFTASQSYRYKL----ALEEIRDSLYL-DGKPHSLRQKHLRNLQIVDLLVELVLLPFHSKIDAAFTE----------------KIYRASFEILHNYMKGSSI---KNSLYFAKYINLFEPKMLENNDLGHKII--EMIAELLRNNQKVLE-CISFQEIFPFIDNLRINQNFRYLEYLETFCVCNGEPMTQNQIKIAVKWLSEDQRGVFLTDRGQNLNLESNVIYIKTKLDSNWMK-LHEFLDITAQIDQENNPLYHQDNKDYFLKQMDLLLALC 2281
            K     E  +N  E ++ LG  + YG ++QL HV + KYI V     + +++N+M + L     + + F I P YK    G+ V   + ++      P+     +    + +  H ++ NL   QS      +   ++  +         + N ++ GD +++ H +   ++  + I       D ++LR+         T+SR        W+V++ +         +W+  +RF+H    +YLS               +  L  S T N     +  PN V                                 F+L P    K    +P   Y R+ H  +  W+HA               +A EK   NL Y +   +   ++ C   R+  + F +  V P E+       ++   L  +  LIK   V  K+++  T        L    + + + D L + D  P   RQK LR  ++++ +  L+  PF  +     TE                +I++  F++ +  +K S +   KN  + A+     + +      +G  ++  + +  +L NN K+LE  +    +  F++ +R N+  ++L+YL   CVC GE   + Q  I    LS   R +F+  +            I  +++  W     + +DI       ++   H    DY+  Q+DLL  +C
Sbjct:  127 KVAADKEREENESEFQKTLGNVIQYGSMVQLLHVKSNKYITVQKNSPAKRERNAMKVYLDRAGNEGSWFIIEPAYKHYAIGDNVSAGNKISL----IPNS-VSTTQAGHVKSQLHLSSFNLLDHQSAAEVNCLNEPTEWQVFMFLLFDENQQNSVKSGDVVRLFHADQQTFLTLDTIPKQNPPTDVVFLRMTNRPSAADATSSR------ALWEVQVVQTNAYRGGTAKWNKAYRFKHLATDMYLSAEPSQVQVKPAMNGRRASLIYSKTNNPMAMYSDGPNGVTNESTDTTQQNIPSVWVLGPTKSEFPEEDANLLFQLDPSTFMKSNKEVPRRSYVRLLHQSSDKWVHAT--------------NATEK--QNLHYSSKNEKGWVKVICEKNRVDKETFALLPVNPDEVRDLDFANDACKALRNFIKLIKIGQVISKESINSTTQLLIDCILFVTNSSDHLADPLKISDFSPSRDRQKLLREQEVLNQVFLLLKAPFLPR--QGTTELGPLLSSPSELSDSRNEIFKTMFQLCYCLLKYSQVSYRKNQEFLAEKFGEIQEQ------IGFDLMAEDTMTAVLHNNPKLLEKYVKTPHVERFVELVRNNRQGKFLDYLADLCVCRGEANKKIQELICTSVLSSKHRDIFMDTK-----------IIDGEIEVGWAPNFRKLVDIAEGAKSNSDDAEHL---DYYRHQLDLLSQMC 793          

HSP 2 Score: 72.4034 bits (176), Expect = 7.100e-12
Identity = 38/94 (40.43%), Postives = 53/94 (56.38%), Query Frame = 3
Query: 7584 VDTFSELRDLKYKTEKDMKETCFICSRAGHDFDQSSSSFEHHVVYEHNMWAYLFYFLHLKEIKINDYFHLDLYVANMLKRENYDFFPINCALSL 7865
            +DTF +LR  K + E+ +K  CFIC      FD  S +FE H   EHN+W YL+Y + L+     ++   + YVA  +K  N D+FP   ALSL
Sbjct: 2707 IDTFGDLRAEKNEKEQILKNNCFICGLDRSRFDNRSVTFETHRETEHNIWHYLYYIVMLQIKDETEFTGPESYVAQCVKDRNLDWFPRMQALSL 2800          
BLAST of Inositol 1,4,5-trisphosphate receptor type 3 vs. Ensembl Fly
Match: Itp-r83A (gene:FBgn0010051 transcript:FBtr0078687)

HSP 1 Score: 86.2705 bits (212), Expect = 5.071e-16
Identity = 72/331 (21.75%), Postives = 145/331 (43.81%), Query Frame = 2
Query:  461 EENDNALENRRNLGKTVHYG-DVIQLRHVYTRKYIHVNIAKTSSKDQNSMILNLQSHNLKSAQFKIVPRYKVKYEGEPVQFMDLVTFESLKAPSHYFHASDLYQIDNFFHGAALNLATEQSGFTLIKSASDTHIMEEDNFLRGGDYIQIIHKEIDGYIESEGIQGGMKKADIYLRIRKSDKFQTLTNSRLSSSANTFWQVE-IEKVRLSTEIGQWSSNFRFRHATNRLYLSVKKDLSVSM---------------------------TKNAT-------------------NPNTVFRLYPQNIDKL--IIPYGRYFRMEHVLTGTWIHAN 1303
            E+  N  EN++ LG ++ YG  V+QL H+ + KY+ VN    S  ++N+M + L ++  + + F I P YK++  G+ V   D V    + A     H +  Y++ +      +N+    + + +  S    H   +++ L+GGD +++ H E + ++  +  +   K+  ++LR          T++  ++S+   W++E ++        G W+S +RF+H     YL+ + ++ VS                            T N+T                   +  +VF L    + +   ++P   Y R++H+ + TW+HA 
Sbjct:  102 EKKQNETENKKLLGTSIQYGRAVVQLLHLKSNKYLTVNKRLPSLLEKNAMRVYLDANGNEGSWFYIKPFYKLRSIGDYVVVGDKVILSPVNADQQNLHVAANYELPDNPGCKEVNVLNSSTSWKI--SLFMEHKENQEHILKGGDVVRLFHAEQEKFLTMDEYK---KQYHVFLRTTGR------TSATAATSSKALWEIEVVQHDSCRGGAGDWNSLYRFKHLATGHYLAAEAEIDVSAGAMSATSASGHDLHLGDCSKDSGLSCSTMNSTINDKPKGKQYRLVSVPYSADIASVFVLDATTMARPDSLVPQSSYVRLQHICSNTWVHAT 421          

HSP 2 Score: 73.9442 bits (180), Expect = 2.392e-12
Identity = 40/114 (35.09%), Postives = 63/114 (55.26%), Query Frame = 3
Query: 7584 VDTFSELRDLKYKTEKDMKETCFICSRAGHDFDQSSSSFEHHVVYEHNMWAYLFYFLHLKEIKINDYFHLDLYVANMLKRENYDFFPINCALSLTAEQEKYSRIDEISRNVKII 7925
            +DTF++LR  K + E  +K TCFICS     FD  + SFE H+  EHNMW YL++ + +K     ++   + YV  M+K    ++FP   A+SL A      +I+  S   +++
Sbjct: 2680 IDTFADLRSEKQQKEAILKTTCFICSLNRSAFDNKTVSFEEHIKSEHNMWHYLYFIVLVKVKDPTEFTGPESYVYAMVKAGILEWFPRLRAMSLAAVDADGEQIELRSMQAQLL 2793          
BLAST of Inositol 1,4,5-trisphosphate receptor type 3 vs. Ensembl Fly
Match: Itp-r83A (gene:FBgn0010051 transcript:FBtr0078686)

HSP 1 Score: 86.2705 bits (212), Expect = 5.701e-16
Identity = 72/331 (21.75%), Postives = 145/331 (43.81%), Query Frame = 2
Query:  461 EENDNALENRRNLGKTVHYG-DVIQLRHVYTRKYIHVNIAKTSSKDQNSMILNLQSHNLKSAQFKIVPRYKVKYEGEPVQFMDLVTFESLKAPSHYFHASDLYQIDNFFHGAALNLATEQSGFTLIKSASDTHIMEEDNFLRGGDYIQIIHKEIDGYIESEGIQGGMKKADIYLRIRKSDKFQTLTNSRLSSSANTFWQVE-IEKVRLSTEIGQWSSNFRFRHATNRLYLSVKKDLSVSM---------------------------TKNAT-------------------NPNTVFRLYPQNIDKL--IIPYGRYFRMEHVLTGTWIHAN 1303
            E+  N  EN++ LG ++ YG  V+QL H+ + KY+ VN    S  ++N+M + L ++  + + F I P YK++  G+ V   D V    + A     H +  Y++ +      +N+    + + +  S    H   +++ L+GGD +++ H E + ++  +  +   K+  ++LR          T++  ++S+   W++E ++        G W+S +RF+H     YL+ + ++ VS                            T N+T                   +  +VF L    + +   ++P   Y R++H+ + TW+HA 
Sbjct:  102 EKKQNETENKKLLGTSIQYGRAVVQLLHLKSNKYLTVNKRLPSLLEKNAMRVYLDANGNEGSWFYIKPFYKLRSIGDYVVVGDKVILSPVNADQQNLHVAANYELPDNPGCKEVNVLNSSTSWKI--SLFMEHKENQEHILKGGDVVRLFHAEQEKFLTMDEYK---KQYHVFLRTTGR------TSATAATSSKALWEIEVVQHDSCRGGAGDWNSLYRFKHLATGHYLAAEAEIDVSAGAMSATSASGHDLHLGDCSKDSGLSCSTMNSTINDKPKGKQYRLVSVPYSADIASVFVLDATTMARPDSLVPQSSYVRLQHICSNTWVHAT 421          

HSP 2 Score: 73.9442 bits (180), Expect = 2.391e-12
Identity = 40/114 (35.09%), Postives = 63/114 (55.26%), Query Frame = 3
Query: 7584 VDTFSELRDLKYKTEKDMKETCFICSRAGHDFDQSSSSFEHHVVYEHNMWAYLFYFLHLKEIKINDYFHLDLYVANMLKRENYDFFPINCALSLTAEQEKYSRIDEISRNVKII 7925
            +DTF++LR  K + E  +K TCFICS     FD  + SFE H+  EHNMW YL++ + +K     ++   + YV  M+K    ++FP   A+SL A      +I+  S   +++
Sbjct: 2671 IDTFADLRSEKQQKEAILKTTCFICSLNRSAFDNKTVSFEEHIKSEHNMWHYLYFIVLVKVKDPTEFTGPESYVYAMVKAGILEWFPRLRAMSLAAVDADGEQIELRSMQAQLL 2784          
BLAST of Inositol 1,4,5-trisphosphate receptor type 3 vs. Ensembl Fly
Match: Itp-r83A (gene:FBgn0010051 transcript:FBtr0344265)

HSP 1 Score: 86.2705 bits (212), Expect = 5.701e-16
Identity = 72/331 (21.75%), Postives = 145/331 (43.81%), Query Frame = 2
Query:  461 EENDNALENRRNLGKTVHYG-DVIQLRHVYTRKYIHVNIAKTSSKDQNSMILNLQSHNLKSAQFKIVPRYKVKYEGEPVQFMDLVTFESLKAPSHYFHASDLYQIDNFFHGAALNLATEQSGFTLIKSASDTHIMEEDNFLRGGDYIQIIHKEIDGYIESEGIQGGMKKADIYLRIRKSDKFQTLTNSRLSSSANTFWQVE-IEKVRLSTEIGQWSSNFRFRHATNRLYLSVKKDLSVSM---------------------------TKNAT-------------------NPNTVFRLYPQNIDKL--IIPYGRYFRMEHVLTGTWIHAN 1303
            E+  N  EN++ LG ++ YG  V+QL H+ + KY+ VN    S  ++N+M + L ++  + + F I P YK++  G+ V   D V    + A     H +  Y++ +      +N+    + + +  S    H   +++ L+GGD +++ H E + ++  +  +   K+  ++LR          T++  ++S+   W++E ++        G W+S +RF+H     YL+ + ++ VS                            T N+T                   +  +VF L    + +   ++P   Y R++H+ + TW+HA 
Sbjct:  102 EKKQNETENKKLLGTSIQYGRAVVQLLHLKSNKYLTVNKRLPSLLEKNAMRVYLDANGNEGSWFYIKPFYKLRSIGDYVVVGDKVILSPVNADQQNLHVAANYELPDNPGCKEVNVLNSSTSWKI--SLFMEHKENQEHILKGGDVVRLFHAEQEKFLTMDEYK---KQYHVFLRTTGR------TSATAATSSKALWEIEVVQHDSCRGGAGDWNSLYRFKHLATGHYLAAEAEIDVSAGAMSATSASGHDLHLGDCSKDSGLSCSTMNSTINDKPKGKQYRLVSVPYSADIASVFVLDATTMARPDSLVPQSSYVRLQHICSNTWVHAT 421          

HSP 2 Score: 73.9442 bits (180), Expect = 2.391e-12
Identity = 40/114 (35.09%), Postives = 63/114 (55.26%), Query Frame = 3
Query: 7584 VDTFSELRDLKYKTEKDMKETCFICSRAGHDFDQSSSSFEHHVVYEHNMWAYLFYFLHLKEIKINDYFHLDLYVANMLKRENYDFFPINCALSLTAEQEKYSRIDEISRNVKII 7925
            +DTF++LR  K + E  +K TCFICS     FD  + SFE H+  EHNMW YL++ + +K     ++   + YV  M+K    ++FP   A+SL A      +I+  S   +++
Sbjct: 2671 IDTFADLRSEKQQKEAILKTTCFICSLNRSAFDNKTVSFEEHIKSEHNMWHYLYFIVLVKVKDPTEFTGPESYVYAMVKAGILEWFPRLRAMSLAAVDADGEQIELRSMQAQLL 2784          
BLAST of Inositol 1,4,5-trisphosphate receptor type 3 vs. Ensembl Fly
Match: RyR (gene:FBgn0011286 transcript:FBtr0088639)

HSP 1 Score: 71.633 bits (174), Expect = 1.504e-11
Identity = 66/250 (26.40%), Postives = 113/250 (45.20%), Query Frame = 3
Query: 7107 WDKSTRFF--VFLYEISLLLSMSIGGIWIPYLYVFHLFNVIHNNQLLKGVIASVTKNGRXXXXXXXXXXXXXXXFSIFAFCFLRSTFSSENYLYADTLVQTFVSLVRFGIVGDLYQYTIPHKYYMKTVDTAFTEFSXXXXXXXXXXXXXXXXXXXXXXXXXVDTFSELRDLKYKTEKDMKETCFICSRAGHDFDQSSSSFEHHVVYEHNMWAYLFYFLHLKEIKINDYFHLDLYVANMLKRENYDFFPIN 7850
            W     F    FLY +    S S+ G +  + +  HL +V    + L+ ++ SVT NG+ L+  ++L+ I++YI+++ AF F R  +  E     D      ++   F +   +                 +  + +I     FFF+ I +  +       +D F ELRD     + +M+  CFIC      FD     F+ HV  EHN+  Y+F+ +HL      +Y   + YV NM ++ ++DFFP+ 
Sbjct: 4849 WKAGVTFTDNAFLYSL-WYFSFSVMGNFNNFFFAAHLLDVAVGFKTLRTILQSVTHNGKQLVLTVMLLTIIVYIYTVIAFNFFRKFYIQEEDEEVDKKCHDMLTCFVFHLYKGVRAGGGIGDEIGDPDGDDYEVYRIIFDITFFFFVIIILLAIIQGLI--IDAFGELRDQLESVKDNMESNCFICGMGKDFFDIVPHGFDTHVQKEHNLANYMFFLMHLINKPDTEYTGQETYVWNMYQQRSWDFFPVG 5095          
BLAST of Inositol 1,4,5-trisphosphate receptor type 3 vs. Ensembl Fly
Match: RyR (gene:FBgn0011286 transcript:FBtr0088638)

HSP 1 Score: 71.633 bits (174), Expect = 1.517e-11
Identity = 66/250 (26.40%), Postives = 113/250 (45.20%), Query Frame = 3
Query: 7107 WDKSTRFF--VFLYEISLLLSMSIGGIWIPYLYVFHLFNVIHNNQLLKGVIASVTKNGRXXXXXXXXXXXXXXXFSIFAFCFLRSTFSSENYLYADTLVQTFVSLVRFGIVGDLYQYTIPHKYYMKTVDTAFTEFSXXXXXXXXXXXXXXXXXXXXXXXXXVDTFSELRDLKYKTEKDMKETCFICSRAGHDFDQSSSSFEHHVVYEHNMWAYLFYFLHLKEIKINDYFHLDLYVANMLKRENYDFFPIN 7850
            W     F    FLY +    S S+ G +  + +  HL +V    + L+ ++ SVT NG+ L+  ++L+ I++YI+++ AF F R  +  E     D      ++   F +   +                 +  + +I     FFF+ I +  +       +D F ELRD     + +M+  CFIC      FD     F+ HV  EHN+  Y+F+ +HL      +Y   + YV NM ++ ++DFFP+ 
Sbjct: 4849 WKAGVTFTDNAFLYSL-WYFSFSVMGNFNNFFFAAHLLDVAVGFKTLRTILQSVTHNGKQLVLTVMLLTIIVYIYTVIAFNFFRKFYIQEEDEEVDKKCHDMLTCFVFHLYKGVRAGGGIGDEIGDPDGDDYEVYRIIFDITFFFFVIIILLAIIQGLI--IDAFGELRDQLESVKDNMESNCFICGMGKDFFDIVPHGFDTHVQKEHNLANYMFFLMHLINKPDTEYTGQETYVWNMYQQRSWDFFPVG 5095          
BLAST of Inositol 1,4,5-trisphosphate receptor type 3 vs. Ensembl Zebrafish
Match: itpr1b (inositol 1,4,5-trisphosphate receptor, type 1b [Source:ZFIN;Acc:ZDB-GENE-070604-2])

HSP 1 Score: 134.42 bits (337), Expect = 1.707e-30
Identity = 213/943 (22.59%), Postives = 392/943 (41.57%), Query Frame = 2
Query:  164 MNDYLSYGDRICLYCE-ETNGFINSNNSSSHYNELRIFSKQDKFNPENVSDIQEIIFEVVIQNRXXXXXXXXXXXXDINNKSENLELKIQAEQAKATVISEENDNALENRRNLGKTVHYGDVIQLRHVYTRKYIHVNIAKTSSKDQNSMILNLQSHNLKSAQFKIVPRYKVKYEGEPVQFMDLVTFESLKAPSHYFHASDLYQIDNFFHGAALNLATEQS-GFTLIKSASDTHIMEEDNFLRGGDYIQIIHKEIDGYIESEGIQGGMKKADIYLRIRKSDKFQTLTNSRLSSSANTFWQVE-IEKVRLSTEIGQWSSNFRFRHATNRLYLSVKKD------------------LSVSMTKNATNPNTVFRLYPQNI--DKLIIPYGRYFRMEHVLTGTWIHANKEQVYVKPNQSKYDDAAEKCLGNLKYETNELRELFCVHQRLYDDAFVVFKVPTEIVESFNLLSGYFPLIKNLIVDRKKAVPFTASQSYRYKLALEEI-----------RDSL-YLDGKPHSLRQKHLRNLQIVDLLVELVLLPFHSKIDA-------------AFTEKIYRASFEILHNYMKGSSIKNSLYFAKYINLFEPKMLENNDLGHKII--EMIAELLRNNQKVLE-CISFQEIFPFIDNLRINQNFRYLEYLETFCVCNGE--PMTQNQIKIAVKWLSEDQRGVFLTDRGQNLNLESNVIYIKTKLDSNWMKLHEFLDITAQIDQENNPLY-----------------------HQDNKD---YFLKQMDLLLALCYGRNQYCTNLIINKLNYISWEQCFAAINSPMIPPYMKTKYFEIIQTMFIDIGRNYAVIESPKFNFIFNQIQGDSSVAVECMFPTPSESVTIK-IFKDLSEWIYNFLEST--PRMISSNKDFNYLIRIVFITINKLIQYGYYDSPSLDRICKSLLKLLN 2746
            M+ +L  GD   LY E  TNGFI++         ++  S      P+   D Q   F +   NRY   K++ K  K   N + +  L  +   A      E+  N  ENR+ LG  + YG+VIQL H+ + KY+ VN    +  ++N+M + L S   + + F I P YK++  G+ V   D V    + A     HAS    +DN       ++    S    L    SD     ++  L+GGD +++ H E + ++  +  +   KK  ++LR   +   Q+ T+   ++S+   W++E ++        G W+S FRF+H     YL+ + D                   S+    +  + +++F L P  +     ++P   Y R+ H+ T TW+H+    +          D  E+    L+  T+ ++E          +AF +  VP   V   +  +    ++ ++    +K       + +  KL LE++           +D L  +  KP+  RQK +R   I+  + +L+  PF    D              A    I R  + +L +  +    KN  Y AK     + +      +G+ ++  + I  LL NN+K+LE  I+  EI  F+  +R N+  R+L+YL   CV   +  P+TQ  I  AV           L     ++ +E+ ++  + +++S    +       ++ID+E   L+                        +D++D   Y+  Q++L   +C  R       I  +L+     +C +  +   +P  ++  +  ++  M +D      V+   K+  ++++I   S +A++      +    IK  F    +++ N+L       +  S+K+ N L   V      LI +G+Y+   L R+ K LL +L+
Sbjct:    5 MSSFLHIGDICSLYAEGSTNGFISTLGLVDDRCVVQPESGDLNNPPKKFRDCQ---FRLCPMNRYSAQKQFWKAAKPGGNSTTDTVLLNKLHHAADL---EKKQNESENRKLLGTVIQYGNVIQLLHLKSNKYLTVNKRLPALLEKNAMRVTLDSAGNEGSWFYIQPFYKLRSIGDSVVIGDKVVLNPVNA-GQPLHASSHQLVDNPGCNEVNSVNCNTSWKIVLFMKWSDN----KEAILKGGDVVRLFHAEQEKFLTCDEHR---KKQHVFLR---TTGRQSATS---ATSSKALWEIEVVQHDPCRGGAGYWNSLFRFKHLATGHYLAAELDSEHEALRARLRTPNEKVMYSLVSVPDGNDISSIFELDPTTLRGGDSLVPRNSYVRLRHLCTNTWVHSTNNPI----------DKEEEKPVMLRIGTSAVKE--------DKEAFAIVPVPPAEVRDLDFANDASKVLASIAGKLEKGTITQNERRFVTKL-LEDLVFFVVDIPNNGQDVLEIMVNKPNRERQKLMREQNILKQIFKLLQAPFTDSGDGPMLRLEELNDQRHAPFRHICRLCYRVLRHSQQDYR-KNQEYIAKQFRFMQKQ------IGYDVLAEDTITALLHNNRKLLEKHITAAEIDTFVSLVRKNREPRFLDYLSDLCVSMNKSIPVTQELICNAV-----------LNPANADILIETKLVLSRFEVESGEGPME------SEIDEEEVWLFWKNSNKEVKSKSIRELAQDAKEGQKDDQDVISYYRYQLNLFARMCLDRQYLAIEKISGQLDVDLILRCMSDED---LPYDLRASFCRLMLHMHVDRDPQEQVMPV-KYARLWSEIP--SKIAIDDYDNDGTSRDEIKERFALTMDFVENYLRDVVLQNVPFSDKEKNKLTFEVVNLARNLIYFGFYNFSDLLRLTKILLAILD 878          

HSP 2 Score: 83.5741 bits (205), Expect = 3.801e-15
Identity = 48/147 (32.65%), Postives = 76/147 (51.70%), Query Frame = 3
Query: 7584 VDTFSELRDLKYKTEKDMKETCFICSRAGHDFDQSSSSFEHHVVYEHNMWAYLFYFLHLKEIKINDYFHLDLYVANMLKRENYDFFPINCALSLT-----AEQEKYSRIDEISRNVKIIVSN----------RQNEEREKLRRTNLF 7979
            +DTF++LR  K K E+ +K TCFIC      FD  + +FE H+  EHNMW YLF+ + +K     ++   + YVA M++  N D+FP   A+SL       EQ +   + E   +   ++SN          +  E+R++ +R  L 
Sbjct: 2557 IDTFADLRSEKQKKEEVLKTTCFICGLERDKFDNKTVTFEEHIKVEHNMWHYLFFIVLVKVKDSTEFTGPESYVAEMIRDHNLDWFPRMRAMSLVSSDAEGEQNEIRSLQEKLESTMKLISNLSSQLTELKEQMTEQRKQKQRIGLL 2703          
BLAST of Inositol 1,4,5-trisphosphate receptor type 3 vs. Ensembl Zebrafish
Match: itpr1b (inositol 1,4,5-trisphosphate receptor, type 1b [Source:ZFIN;Acc:ZDB-GENE-070604-2])

HSP 1 Score: 133.65 bits (335), Expect = 2.801e-30
Identity = 213/943 (22.59%), Postives = 392/943 (41.57%), Query Frame = 2
Query:  164 MNDYLSYGDRICLYCE-ETNGFINSNNSSSHYNELRIFSKQDKFNPENVSDIQEIIFEVVIQNRXXXXXXXXXXXXDINNKSENLELKIQAEQAKATVISEENDNALENRRNLGKTVHYGDVIQLRHVYTRKYIHVNIAKTSSKDQNSMILNLQSHNLKSAQFKIVPRYKVKYEGEPVQFMDLVTFESLKAPSHYFHASDLYQIDNFFHGAALNLATEQS-GFTLIKSASDTHIMEEDNFLRGGDYIQIIHKEIDGYIESEGIQGGMKKADIYLRIRKSDKFQTLTNSRLSSSANTFWQVE-IEKVRLSTEIGQWSSNFRFRHATNRLYLSVKKD------------------LSVSMTKNATNPNTVFRLYPQNI--DKLIIPYGRYFRMEHVLTGTWIHANKEQVYVKPNQSKYDDAAEKCLGNLKYETNELRELFCVHQRLYDDAFVVFKVPTEIVESFNLLSGYFPLIKNLIVDRKKAVPFTASQSYRYKLALEEI-----------RDSL-YLDGKPHSLRQKHLRNLQIVDLLVELVLLPFHSKIDA-------------AFTEKIYRASFEILHNYMKGSSIKNSLYFAKYINLFEPKMLENNDLGHKII--EMIAELLRNNQKVLE-CISFQEIFPFIDNLRINQNFRYLEYLETFCVCNGE--PMTQNQIKIAVKWLSEDQRGVFLTDRGQNLNLESNVIYIKTKLDSNWMKLHEFLDITAQIDQENNPLY-----------------------HQDNKD---YFLKQMDLLLALCYGRNQYCTNLIINKLNYISWEQCFAAINSPMIPPYMKTKYFEIIQTMFIDIGRNYAVIESPKFNFIFNQIQGDSSVAVECMFPTPSESVTIK-IFKDLSEWIYNFLEST--PRMISSNKDFNYLIRIVFITINKLIQYGYYDSPSLDRICKSLLKLLN 2746
            M+ +L  GD   LY E  TNGFI++         ++  S      P+   D Q   F +   NRY   K++ K  K   N + +  L  +   A      E+  N  ENR+ LG  + YG+VIQL H+ + KY+ VN    +  ++N+M + L S   + + F I P YK++  G+ V   D V    + A     HAS    +DN       ++    S    L    SD     ++  L+GGD +++ H E + ++  +  +   KK  ++LR   +   Q+ T+   ++S+   W++E ++        G W+S FRF+H     YL+ + D                   S+    +  + +++F L P  +     ++P   Y R+ H+ T TW+H+    +          D  E+    L+  T+ ++E          +AF +  VP   V   +  +    ++ ++    +K       + +  KL LE++           +D L  +  KP+  RQK +R   I+  + +L+  PF    D              A    I R  + +L +  +    KN  Y AK     + +      +G+ ++  + I  LL NN+K+LE  I+  EI  F+  +R N+  R+L+YL   CV   +  P+TQ  I  AV           L     ++ +E+ ++  + +++S    +       ++ID+E   L+                        +D++D   Y+  Q++L   +C  R       I  +L+     +C +  +   +P  ++  +  ++  M +D      V+   K+  ++++I   S +A++      +    IK  F    +++ N+L       +  S+K+ N L   V      LI +G+Y+   L R+ K LL +L+
Sbjct:    5 MSSFLHIGDICSLYAEGSTNGFISTLGLVDDRCVVQPESGDLNNPPKKFRDCQ---FRLCPMNRYSAQKQFWKAAKPGGNSTTDTVLLNKLHHAADL---EKKQNESENRKLLGTVIQYGNVIQLLHLKSNKYLTVNKRLPALLEKNAMRVTLDSAGNEGSWFYIQPFYKLRSIGDSVVIGDKVVLNPVNA-GQPLHASSHQLVDNPGCNEVNSVNCNTSWKIVLFMKWSDN----KEAILKGGDVVRLFHAEQEKFLTCDEHR---KKQHVFLR---TTGRQSATS---ATSSKALWEIEVVQHDPCRGGAGYWNSLFRFKHLATGHYLAAELDSEHEALRARLRTPNEKVMYSLVSVPDGNDISSIFELDPTTLRGGDSLVPRNSYVRLRHLCTNTWVHSTNNPI----------DKEEEKPVMLRIGTSAVKE--------DKEAFAIVPVPPAEVRDLDFANDASKVLASIAGKLEKGTITQNERRFVTKL-LEDLVFFVVDIPNNGQDVLEIMVNKPNRERQKLMREQNILKQIFKLLQAPFTDSGDGPMLRLEELNDQRHAPFRHICRLCYRVLRHSQQDYR-KNQEYIAKQFRFMQKQ------IGYDVLAEDTITALLHNNRKLLEKHITAAEIDTFVSLVRKNREPRFLDYLSDLCVSMNKSIPVTQELICNAV-----------LNPANADILIETKLVLSRFEVESGEGPME------SEIDEEEVWLFWKNSNKEVKSKSIRELAQDAKEGQKDDQDVISYYRYQLNLFARMCLDRQYLAIEKISGQLDVDLILRCMSDED---LPYDLRASFCRLMLHMHVDRDPQEQVM-PVKYARLWSEIP--SKIAIDDYDNDGTSRDEIKERFALTMDFVENYLRDVVLQNVPFSDKEKNKLTFEVVNLARNLIYFGFYNFSDLLRLTKILLAILD 878          

HSP 2 Score: 83.5741 bits (205), Expect = 4.185e-15
Identity = 48/147 (32.65%), Postives = 76/147 (51.70%), Query Frame = 3
Query: 7584 VDTFSELRDLKYKTEKDMKETCFICSRAGHDFDQSSSSFEHHVVYEHNMWAYLFYFLHLKEIKINDYFHLDLYVANMLKRENYDFFPINCALSLT-----AEQEKYSRIDEISRNVKIIVSN----------RQNEEREKLRRTNLF 7979
            +DTF++LR  K K E+ +K TCFIC      FD  + +FE H+  EHNMW YLF+ + +K     ++   + YVA M++  N D+FP   A+SL       EQ +   + E   +   ++SN          +  E+R++ +R  L 
Sbjct: 2478 IDTFADLRSEKQKKEEVLKTTCFICGLERDKFDNKTVTFEEHIKVEHNMWHYLFFIVLVKVKDSTEFTGPESYVAEMIRDHNLDWFPRMRAMSLVSSDAEGEQNEIRSLQEKLESTMKLISNLSSQLTELKEQMTEQRKQKQRIGLL 2624          
BLAST of Inositol 1,4,5-trisphosphate receptor type 3 vs. Ensembl Zebrafish
Match: itpr1b (inositol 1,4,5-trisphosphate receptor, type 1b [Source:ZFIN;Acc:ZDB-GENE-070604-2])

HSP 1 Score: 133.65 bits (335), Expect = 2.976e-30
Identity = 213/943 (22.59%), Postives = 392/943 (41.57%), Query Frame = 2
Query:  164 MNDYLSYGDRICLYCE-ETNGFINSNNSSSHYNELRIFSKQDKFNPENVSDIQEIIFEVVIQNRXXXXXXXXXXXXDINNKSENLELKIQAEQAKATVISEENDNALENRRNLGKTVHYGDVIQLRHVYTRKYIHVNIAKTSSKDQNSMILNLQSHNLKSAQFKIVPRYKVKYEGEPVQFMDLVTFESLKAPSHYFHASDLYQIDNFFHGAALNLATEQS-GFTLIKSASDTHIMEEDNFLRGGDYIQIIHKEIDGYIESEGIQGGMKKADIYLRIRKSDKFQTLTNSRLSSSANTFWQVE-IEKVRLSTEIGQWSSNFRFRHATNRLYLSVKKD------------------LSVSMTKNATNPNTVFRLYPQNI--DKLIIPYGRYFRMEHVLTGTWIHANKEQVYVKPNQSKYDDAAEKCLGNLKYETNELRELFCVHQRLYDDAFVVFKVPTEIVESFNLLSGYFPLIKNLIVDRKKAVPFTASQSYRYKLALEEI-----------RDSL-YLDGKPHSLRQKHLRNLQIVDLLVELVLLPFHSKIDA-------------AFTEKIYRASFEILHNYMKGSSIKNSLYFAKYINLFEPKMLENNDLGHKII--EMIAELLRNNQKVLE-CISFQEIFPFIDNLRINQNFRYLEYLETFCVCNGE--PMTQNQIKIAVKWLSEDQRGVFLTDRGQNLNLESNVIYIKTKLDSNWMKLHEFLDITAQIDQENNPLY-----------------------HQDNKD---YFLKQMDLLLALCYGRNQYCTNLIINKLNYISWEQCFAAINSPMIPPYMKTKYFEIIQTMFIDIGRNYAVIESPKFNFIFNQIQGDSSVAVECMFPTPSESVTIK-IFKDLSEWIYNFLEST--PRMISSNKDFNYLIRIVFITINKLIQYGYYDSPSLDRICKSLLKLLN 2746
            M+ +L  GD   LY E  TNGFI++         ++  S      P+   D Q   F +   NRY   K++ K  K   N + +  L  +   A      E+  N  ENR+ LG  + YG+VIQL H+ + KY+ VN    +  ++N+M + L S   + + F I P YK++  G+ V   D V    + A     HAS    +DN       ++    S    L    SD     ++  L+GGD +++ H E + ++  +  +   KK  ++LR   +   Q+ T+   ++S+   W++E ++        G W+S FRF+H     YL+ + D                   S+    +  + +++F L P  +     ++P   Y R+ H+ T TW+H+    +          D  E+    L+  T+ ++E          +AF +  VP   V   +  +    ++ ++    +K       + +  KL LE++           +D L  +  KP+  RQK +R   I+  + +L+  PF    D              A    I R  + +L +  +    KN  Y AK     + +      +G+ ++  + I  LL NN+K+LE  I+  EI  F+  +R N+  R+L+YL   CV   +  P+TQ  I  AV           L     ++ +E+ ++  + +++S    +       ++ID+E   L+                        +D++D   Y+  Q++L   +C  R       I  +L+     +C +  +   +P  ++  +  ++  M +D      V+   K+  ++++I   S +A++      +    IK  F    +++ N+L       +  S+K+ N L   V      LI +G+Y+   L R+ K LL +L+
Sbjct:    5 MSSFLHIGDICSLYAEGSTNGFISTLGLVDDRCVVQPESGDLNNPPKKFRDCQ---FRLCPMNRYSAQKQFWKAAKPGGNSTTDTVLLNKLHHAADL---EKKQNESENRKLLGTVIQYGNVIQLLHLKSNKYLTVNKRLPALLEKNAMRVTLDSAGNEGSWFYIQPFYKLRSIGDSVVIGDKVVLNPVNA-GQPLHASSHQLVDNPGCNEVNSVNCNTSWKIVLFMKWSDN----KEAILKGGDVVRLFHAEQEKFLTCDEHR---KKQHVFLR---TTGRQSATS---ATSSKALWEIEVVQHDPCRGGAGYWNSLFRFKHLATGHYLAAELDSEHEALRARLRTPNEKVMYSLVSVPDGNDISSIFELDPTTLRGGDSLVPRNSYVRLRHLCTNTWVHSTNNPI----------DKEEEKPVMLRIGTSAVKE--------DKEAFAIVPVPPAEVRDLDFANDASKVLASIAGKLEKGTITQNERRFVTKL-LEDLVFFVVDIPNNGQDVLEIMVNKPNRERQKLMREQNILKQIFKLLQAPFTDSGDGPMLRLEELNDQRHAPFRHICRLCYRVLRHSQQDYR-KNQEYIAKQFRFMQKQ------IGYDVLAEDTITALLHNNRKLLEKHITAAEIDTFVSLVRKNREPRFLDYLSDLCVSMNKSIPVTQELICNAV-----------LNPANADILIETKLVLSRFEVESGEGPME------SEIDEEEVWLFWKNSNKEVKSKSIRELAQDAKEGQKDDQDVISYYRYQLNLFARMCLDRQYLAIEKISGQLDVDLILRCMSDED---LPYDLRASFCRLMLHMHVDRDPQEQVM-PVKYARLWSEIP--SKIAIDDYDNDGTSRDEIKERFALTMDFVENYLRDVVLQNVPFSDKEKNKLTFEVVNLARNLIYFGFYNFSDLLRLTKILLAILD 878          

HSP 2 Score: 83.5741 bits (205), Expect = 3.770e-15
Identity = 48/135 (35.56%), Postives = 77/135 (57.04%), Query Frame = 3
Query: 7584 VDTFSELRDLKYKTEKDMKETCFICSRAGHDFDQSSSSFEHHVVYEHNMWAYLFYFLHLKEIKINDYFHLDLYVANMLKRENYDFFPINCALSLT-----AEQEKYSRIDE-ISRNVKII--VSNRQNEEREKLR 7964
            +DTF++LR  K K E+ +K TCFIC      FD  + +FE H+  EHNMW YLF+ + +K     ++   + YVA M++  N D+FP   A+SL       EQ +   + E +   +K+I  +S++  E +E++R
Sbjct: 2442 IDTFADLRSEKQKKEEVLKTTCFICGLERDKFDNKTVTFEEHIKVEHNMWHYLFFIVLVKVKDSTEFTGPESYVAEMIRDHNLDWFPRMRAMSLVSSDAEGEQNEIRSLQEKLESTMKLISNLSSQLTELKEQVR 2576          
BLAST of Inositol 1,4,5-trisphosphate receptor type 3 vs. Ensembl Zebrafish
Match: itpr1b (inositol 1,4,5-trisphosphate receptor, type 1b [Source:ZFIN;Acc:ZDB-GENE-070604-2])

HSP 1 Score: 129.028 bits (323), Expect = 7.120e-29
Identity = 212/950 (22.32%), Postives = 392/950 (41.26%), Query Frame = 2
Query:  164 MNDYLSYGDRICLYCE-ETNGFINSNNSSSHYNELRIFSKQDKFNPENVSDIQEIIFEVVIQNRXXXXXXXXXXXXDINNKSENLELKIQAEQAKATVISEENDNALENRRNLGKTVHYGDVIQLRHVYTRKYIHVNIAKTSSKDQNSMILNLQSHNLKSAQFKIVPRYKVKYEGEPVQFMDLVTFESLKAPSHYFHASDLYQIDNFFHGAALNLATEQS-GFTLIKSASDTHIMEEDNFLRGGDYIQIIHKEIDGYIESEGIQGGMKKADIYLRIRKSDKFQTLTNSRLSSSANTFWQVE-IEKVRLSTEIGQWSSNFRFRHATNRLYLSVKKD-------------------------LSVSMTKNATNPNTVFRLYPQNI--DKLIIPYGRYFRMEHVLTGTWIHANKEQVYVKPNQSKYDDAAEKCLGNLKYETNELRELFCVHQRLYDDAFVVFKVPTEIVESFNLLSGYFPLIKNLIVDRKKAVPFTASQSYRYKLALEEI-----------RDSL-YLDGKPHSLRQKHLRNLQIVDLLVELVLLPFHSKIDA-------------AFTEKIYRASFEILHNYMKGSSIKNSLYFAKYINLFEPKMLENNDLGHKII--EMIAELLRNNQKVLE-CISFQEIFPFIDNLRINQNFRYLEYLETFCVCNGE--PMTQNQIKIAVKWLSEDQRGVFLTDRGQNLNLESNVIYIKTKLDSNWMKLHEFLDITAQIDQENNPLY-----------------------HQDNKD---YFLKQMDLLLALCYGRNQYCTNLIINKLNYISWEQCFAAINSPMIPPYMKTKYFEIIQTMFIDIGRNYAVIESPKFNFIFNQIQGDSSVAVECMFPTPSESVTIK-IFKDLSEWIYNFLEST--PRMISSNKDFNYLIRIVFITINKLIQYGYYDSPSLDRICKSLLKLLN 2746
            M+ +L  GD   LY E  TNGFI++         ++  S      P+   D Q   F +   NRY   K++ K  K   N + +  L  +   A      E+  N  ENR+ LG  + YG+VIQL H+ + KY+ VN    +  ++N+M + L S   + + F I P YK++  G+ V   D V    + A     HAS    +DN       ++    S    L    SD     ++  L+GGD +++ H E + ++  +  +   KK  ++LR   +   Q+ T+   ++S+   W++E ++        G W+S FRF+H     YL+ + +                          S+    +  + +++F L P  +     ++P   Y R+ H+ T TW+H+    +          D  E+    L+  T+ ++E          +AF +  VP   V   +  +    ++ ++    +K       + +  KL LE++           +D L  +  KP+  RQK +R   I+  + +L+  PF    D              A    I R  + +L +  +    KN  Y AK     + +      +G+ ++  + I  LL NN+K+LE  I+  EI  F+  +R N+  R+L+YL   CV   +  P+TQ  I  AV           L     ++ +E+ ++  + +++S    +       ++ID+E   L+                        +D++D   Y+  Q++L   +C  R       I  +L+     +C +  +   +P  ++  +  ++  M +D      V+   K+  ++++I   S +A++      +    IK  F    +++ N+L       +  S+K+ N L   V      LI +G+Y+   L R+ K LL +L+
Sbjct:    5 MSSFLHIGDICSLYAEGSTNGFISTLGLVDDRCVVQPESGDLNNPPKKFRDCQ---FRLCPMNRYSAQKQFWKAAKPGGNSTTDTVLLNKLHHAADL---EKKQNESENRKLLGTVIQYGNVIQLLHLKSNKYLTVNKRLPALLEKNAMRVTLDSAGNEGSWFYIQPFYKLRSIGDSVVIGDKVVLNPVNA-GQPLHASSHQLVDNPGCNEVNSVNCNTSWKIVLFMKWSDN----KEAILKGGDVVRLFHAEQEKFLTCDEHR---KKQHVFLR---TTGRQSATS---ATSSKALWEIEVVQHDPCRGGAGYWNSLFRFKHLATGHYLAAEVNPDYEEESQESRSSVTRLRTPNEKVMYSLVSVPDGNDISSIFELDPTTLRGGDSLVPRNSYVRLRHLCTNTWVHSTNNPI----------DKEEEKPVMLRIGTSAVKE--------DKEAFAIVPVPPAEVRDLDFANDASKVLASIAGKLEKGTITQNERRFVTKL-LEDLVFFVVDIPNNGQDVLEIMVNKPNRERQKLMREQNILKQIFKLLQAPFTDSGDGPMLRLEELNDQRHAPFRHICRLCYRVLRHSQQDYR-KNQEYIAKQFRFMQKQ------IGYDVLAEDTITALLHNNRKLLEKHITAAEIDTFVSLVRKNREPRFLDYLSDLCVSMNKSIPVTQELICNAV-----------LNPANADILIETKLVLSRFEVESGEGPME------SEIDEEEVWLFWKNSNKEVKSKSIRELAQDAKEGQKDDQDVISYYRYQLNLFARMCLDRQYLAIEKISGQLDVDLILRCMSDED---LPYDLRASFCRLMLHMHVDRDPQEQVMPV-KYARLWSEIP--SKIAIDDYDNDGTSRDEIKERFALTMDFVENYLRDVVLQNVPFSDKEKNKLTFEVVNLARNLIYFGFYNFSDLLRLTKILLAILD 885          

HSP 2 Score: 83.9593 bits (206), Expect = 3.437e-15
Identity = 48/135 (35.56%), Postives = 77/135 (57.04%), Query Frame = 3
Query: 7584 VDTFSELRDLKYKTEKDMKETCFICSRAGHDFDQSSSSFEHHVVYEHNMWAYLFYFLHLKEIKINDYFHLDLYVANMLKRENYDFFPINCALSLT-----AEQEKYSRIDE-ISRNVKII--VSNRQNEEREKLR 7964
            +DTF++LR  K K E+ +K TCFIC      FD  + +FE H+  EHNMW YLF+ + +K     ++   + YVA M++  N D+FP   A+SL       EQ +   + E +   +K+I  +S++  E +E++R
Sbjct: 2437 IDTFADLRSEKQKKEEVLKTTCFICGLERDKFDNKTVTFEEHIKVEHNMWHYLFFIVLVKVKDSTEFTGPESYVAEMIRDHNLDWFPRMRAMSLVSSDAEGEQNEIRSLQEKLESTMKLISNLSSQLTELKEQVR 2571          
BLAST of Inositol 1,4,5-trisphosphate receptor type 3 vs. Ensembl Zebrafish
Match: itpr2 (inositol 1,4,5-trisphosphate receptor, type 2 [Source:ZFIN;Acc:ZDB-GENE-050419-192])

HSP 1 Score: 128.642 bits (322), Expect = 9.950e-29
Identity = 220/965 (22.80%), Postives = 403/965 (41.76%), Query Frame = 2
Query:  173 YLSYGDRICLYCEET-NGFINSNNSSSHYNELRIFSKQDKFNPEN------VSDIQEIIFEVVIQNRXXXXXX--XXXXXXDINNKSENLELKIQAEQAKATVISEENDNALENRRNLGKTVHYGDVIQLRHVYTRKYIHVNIAKTSSKDQNSMILNLQSHNLKSAQFKIVPRYKVKYEGEPVQFMDLVTFESLKAPSHYFHASDLYQIDNFFHGA----ALNLATEQSGFTLIKSASDTHIMEEDNFLRGGDYIQIIHKEIDGYIESEGIQGGMKKADIYLRIRKSDKFQTLTNSRLSS-SANTFWQVEI---EKVRLSTEIGQWSSNFRFRHATNRLYLSVK-----KDLSVSM-TKNATNPNTVFRLYPQNIDKL-----------------------------IIPYGRYFRMEHVLTGTWIHANKEQVYVKPNQSKYDDAAEKCLGNLKYETNELRELFCVHQRLYDDAFVVFKVPTEIVESFNLLSGYFPLIKNLIVDRKKAVP-FTASQSYRYKLALEEIRDSLYLDG---------------KPHSLRQKHLRNLQIVDLLVELVLLPFHSKIDAAFTE---------KIYRASFEILHNYMKGSS---IKNSLYFAKYINLFEPKMLENNDLGHKII--EMIAELLRNNQKVLE-CISFQEIFPFIDNLRINQNFRYLEYLETFCVCNGEPMTQNQIKIAVKWLSEDQRGVFLTDR---GQNLNLESNVIYIKTKLDSNWMKLHEFLDITAQIDQENNP----LYH--QDNKD----------YFLKQMDLLLALCYGRNQYCTNLIINKLNY-ISWEQCFAAINSPMIPPYMKTKYFEIIQTMFIDIGRNYAVIESPKFNFIFNQIQGDSSV-AVECMFPTPSESVTIKIFKDLSEWIYNFLE---STPRMISSNKDFNYLIRIVFITINKLIQYGYYDSPSLDRICKSLLKLLN 2746
            +L  GD + LY E T NGFI++         L +   +    PE           ++ +F+V   NRY   ++    K  K  NN   +L  K+Q     A +  ++ND+  EN++ LG+ V Y  VIQL H+ + KY+ VN    +  ++N+M ++L     + + F I P +K++ EG+ V   D V    + A     HAS++  +DN   G     ALN  T     TL    S+      D+ L+GGD +++ H E + ++  +  +   K+  ++LR        TL  S  S+ S+   W+VE+   +  R     GQW+S FRF+H     YL+ +     KD + S+ TKN TN  +++       DK+                             ++P   Y R+ ++ T TW+ +    +          D  E+    LK  T  ++E          +AF +  VP   V   +  +    ++++ +  R   +  + A+   R+ + L E  D ++  G                P+  RQK +R   I+  +  ++  PF    D+   +           ++   ++ +  ++ S     KN  Y AK  ++ + +      +G++I+  + I  LL NN+K+LE  I+ +EI  F+  LR N+  R+L+YL   CV N   +   Q  I    L+     + +  +       +LES++++   + +  W+           ID    P    + H  QD KD          Y+  Q++L   +C  R QY   L IN+++  +  +     +    +P  ++  +  ++  M +D     AV+   ++  ++ +I    SV   +  F   S     + F     ++  +L+   S P      +     + +V +  N L+ +G+Y    L  + ++LL +L+
Sbjct:    8 FLHIGDIVSLYAEGTVNGFIST---------LGLVDDRCVVQPETGDLTNPPKKFRDCLFKVCPMNRYSAQRQFWKAKQGKHGNNTQADLFKKLQH---AAELEQKQNDS--ENKKLLGEVVKYSRVIQLLHIKSNKYLTVNKRLPALLEKNAMRVSLDPSGNEGSWFYIQPFWKLRSEGDNVVVGDKVVLMPVNA-GQPLHASNIELLDN--RGCKEVNALNCNTSWK-VTLFMKFSEYR----DDILKGGDVVRLFHAEQEKFLTCDEYK---KQQYVFLRT-------TLRQSATSATSSKALWEVEVVHYDPCRGGA--GQWNSLFRFKHLATGHYLAAEVNPDFKDRTDSITTKNETNTESLYSKKKWQADKIPYTLVAVPHGNDIASLFELDATTLQRADCLVPRNSYVRLRNLCTNTWVTSTNIPI----------DVEEERPVMLKIGTCHMKE--------DKEAFSINSVPLSEVRDLDFANDANKVLESFV--RILGISNYAAANERRFTIKLLE--DLIFFVGDVPNNGQDVLSVVISNPNRERQKLMREQNILAQIFGILKAPFSEIKDSPMPKLEDVGEQRNSAFKYMLQLCYRTLRHSQQDYRKNQEYIAKNFSIMQAQ------IGYEILAEDTITALLHNNRKLLEKHITAREIETFVKLLRRNREPRFLDYLSDLCVSNKTAIPVTQELICKFMLNPTNADILIQTKLIQHTETSLESSLLHDDVEDEEVWLYW---------IDHHKEPHGKSIRHLAQDAKDGQKLDTDIITYYRCQLNLFAKMCLDR-QY---LAINQISIPLPVDLILRCMFDDCLPYNLRASFCRLMLHMHVDRDPQEAVVPV-RYARLWTEIPSKISVNEYDYEFRDTSREEMKRKFAPTMHFVDEYLKDVVSQPDPFGDREKNELTLEVVHLARN-LVYFGFYSFNELLSLTRTLLAILD 895          
BLAST of Inositol 1,4,5-trisphosphate receptor type 3 vs. Ensembl Xenopus
Match: c1qbp (complement component 1, q subcomponent binding protein [Source:Xenbase;Acc:XB-GENE-973232])

HSP 1 Score: 134.806 bits (338), Expect = 1.775e-30
Identity = 224/933 (24.01%), Postives = 397/933 (42.55%), Query Frame = 2
Query:  164 MNDYLSYGDRICLYCEET-NGFINSNNSSSHYNELRIFSKQDKFNPENVSD-IQEIIFEVVIQNRXXXXXXXXXXXXDINNKSENLELKIQAEQAKATVISEENDNALENRRNLGKTVHYGDVIQLRHVYTRKYIHVNIAKTSSKDQNSMILNLQSHNLKSAQFKIVPRYKVKYEGEPVQFMDLVTFESLKAPSHYFHASDLYQIDNFFHGA----ALNLATEQSGFTLIKSASDTHIMEEDNFLRGGDYIQIIHKEIDGYIESEGIQGGMKKADIYLRIRKSDKFQTLTNSRLSSSANTFWQVE-IEKVRLSTEIGQWSSNFRFRHATNRLYLS--VKKDLSVSMTKNATNP----------------------NTVFRLYPQNI--DKLIIPYGRYFRMEHVLTGTWIHANKEQVYVKPNQSKYDDAAEKCLGNLKYETNELRELFCVHQRLYDDAFVVFKVPTEIVESFNLLSGYFPLIKNLIVDRKKAVPFTASQSYRYKLA--LEEI-----------RDSL-YLDGKPHSLRQKHLRNLQIVDLLVELVLLPFHSKIDA-------------AFTEKIYRASFEILHNYMKGSSIKNSLYFAKYINLFEPKMLENNDLGHKII--EMIAELLRNNQKVLE-CISFQEIFPFIDNLRINQNFRYLEYLETFCVCNGE--PMTQNQIKIAVKWLSEDQRGVFLTDRGQNLNLESNVIYIKTKL---DSNWMKLHEFLDITAQIDQENNPLYHQDNKDYFLKQMDLLLALCYGRNQYCTNLIINKLNYISWEQCFAAINSPMIPPYMKTKYFEIIQTMFIDIGRNYAVIESP-KFNFIFNQIQGDSSVAVECMFPTPSESVTIK-IFKDLSEWIYNFLEST--PRMISSNKDFNYLIRIVFITINKLIQYGYYDSPSLDRICKSLLKLLN 2746
            M+ +L  GD + LY E + NGFIN+          R   + D  +  N     ++ +F +   NRY   K++ K  K   + + +  L  +   A      E+  N  ENR+ LG  + YG+VIQL H+ + KY+ VN    +  ++N+M + L     + + F I P YK++  G+ V   D V    + A     HAS     DN   G     ++N  T       +K + +     +D+ L+GGD +++ H E + ++  +  +   KK  ++LR   +   Q+ T+   ++S+   W+VE ++        G W+S FRF+H     YL+  V   L +    +  N                       +++F L P  +     ++P   Y R+ H+ T TW+H+           S  D   EK +  L+  T+ ++E          +AF +  V    V   +  +    ++ ++    +K    T +Q+ R  +   LEE+           +D L  L  KP+  RQK +R   I+  + +L+  PF    D              A    I R  + +L +  +    KN  Y AK     + +      +G+ ++  + I  LL NN+K+LE  I+  EI  F+  +R N+  R+L+YL   CV   +  P+TQ  I  AV  L+     + +   G++  LE+     +  L   DSN     + +   AQ D +      QD  +Y+  Q++L   +C  R     N I  +L+     +C +  N   +P  ++  +  ++  M +D  R+     +P K+  ++++I   S +A++    + +    IK  F    E++  +L      R   ++K+ N L   V      LI +G+Y+   L R+ K LL +L+
Sbjct:    5 MSSFLHVGDIVSLYAEGSVNGFINTLGLVDD----RCVVQPDAGDLNNPPKKFRDCLFRLCPMNRYSAQKQFWKAAKPGASSTTDTVLLNKLHHAADL---EKKQNETENRKLLGTVIQYGNVIQLLHLKSNKYLTVNKRLPALLEKNAMRVTLDEAGNEGSWFYIQPFYKLRSIGDSVVIGDKVVLNPVNA-GQPLHASSHQLADN--PGCNEVNSVNCNTSWKIVLFMKWSDN-----KDDILKGGDVVRLFHAEQEKFLTCDEHR---KKQYVFLR---TTGRQSATS---ATSSKALWEVEVVQHDPCRGGAGYWNSLFRFKHLATGHYLAAEVSGLLKIDAEPDGGNARMQMVPEKMMCTLISVPEGNDISSIFELDPTTLRGGDSLVPRNSYVRLRHLCTNTWVHS---------TNSPIDKDEEKPV-MLRIGTSPVKE--------DKEAFAIVPVSPAEVRDLDFANDASKVLSSIAGKLEKG---TITQNERRSVTKLLEELVYFVTGLVNAGQDILEVLVNKPNRERQKLMREQNILKQIFKLLQAPFTDSGDGPMLRLEELGDQRHAPFRHICRLCYRVLRHSQQDYR-KNQEYIAKQFGFMQKQ------IGYDVLAEDTITALLHNNRKLLEKHITAAEIDTFVSLVRKNREPRFLDYLSDLCVSMNKSIPVTQELICKAV--LNPANADILIETNGES-PLETGEDEEEVWLFWRDSNKEIRSKSVRELAQ-DAKEGQKEDQDVLNYYRYQLNLFARMCLDRQYLAINEISGQLDVDLILRCMSDEN---LPFDLRASFCRLMLHMHVD--RDPQEQVTPVKYARLWSEIP--SEIAIDDYDSSGTSRDDIKERFAQTMEFVEEYLRDVVGQRFPFADKEKNKLTFEVVNLARNLIYFGFYNFSDLLRLTKILLAILD 874          

HSP 2 Score: 86.6557 bits (213), Expect = 7.738e-16
Identity = 50/147 (34.01%), Postives = 76/147 (51.70%), Query Frame = 3
Query: 7584 VDTFSELRDLKYKTEKDMKETCFICSRAGHDFDQSSSSFEHHVVYEHNMWAYLFYFLHLKEIKINDYFHLDLYVANMLKRENYDFFPINCALSLT-----AEQEKYSRIDEISRNVKIIVSN----------RQNEEREKLRRTNLF 7979
            +DTF++LR  K K E+ +K TCFIC      FD  + +FE H+  EHNMW YLF+ + +K     +Y   + YVA M+K  N D+FP   A+SL       EQ +   + E   +   +V+N          +  E+R++ +R  L 
Sbjct: 2444 IDTFADLRSEKQKKEEVLKTTCFICGLERDKFDNKTVTFEEHIKEEHNMWHYLFFIVLVKVKDSTEYTGPESYVAEMIKERNLDWFPRMRAMSLVSSDSEGEQNELRNLQEKLESTMRLVTNLSSQLSELKDQMTEQRKQKQRIGLL 2590          
BLAST of Inositol 1,4,5-trisphosphate receptor type 3 vs. Ensembl Xenopus
Match: sfi1 (SFI1 centrin binding protein [Source:Xenbase;Acc:XB-GENE-5749440])

HSP 1 Score: 134.42 bits (337), Expect = 2.520e-30
Identity = 178/692 (25.72%), Postives = 299/692 (43.21%), Query Frame = 2
Query:  164 MNDYLSYGDRICLYCEET-NGFINS-----NNSSSHYNELRIFSKQDKFNPENVSDIQEIIFEVVIQNRXXXXXXX-XXXXXDINNKSENLELKIQAEQAKATVISEENDNALENRRNLGKTVHYGDVIQLRHVYTRKYIHVNIAKTSSKDQNSMILNLQSHNLKSAQFKIVPRYKVKYEGEPVQFMDLVTFESLKAPSHYFHASDLYQIDNFFHGA----ALNLATEQSGFTLIKSASDTHIMEEDNFLRGGDYIQIIHKEIDGYIESEGIQGGMKKADIYLRIRKSDKFQTLTNSRLSS-SANTFWQVEI---EKVRLSTEIGQWSSNFRFRHATNRLYLSVKKDLSVSMTK------------NATNPNTVFRLYPQNIDKL-----IIPYGRYFRMEHVLTGTWIHANKEQVYVKPNQSKYDDAAEKCLGNLKYETNELRELFCVHQRLYDDAFVVFKVPTEIVESFNLLSGYFPLIKNLIVDRKKAVPFTASQSYRYKLALEEIRDSLY------------LD---GKPHSLRQKHLRNLQIVDLLVELVLLPFHSKIDA--------------AFTEKIYRASFEILHNYMKGSSIKNSLYFAKYINLFEPKMLENNDLGHKII--EMIAELLRNNQKVLE-CISFQEIFPFIDNLRINQNFRYLEYLETFCVCNGE--PMTQNQI 2041
            M+ +L  GD + LY E + NGFI++     +    H +   + +   KF        ++ +F+V   NRY   K++         N +E   LK     A+     E+  N  ENR+ LG+ V Y +VIQL H+ + KY+ VN    +  ++N+M ++L     + + F I P +K++ EG+ V   D V    + A     HAS++  +DN   G     A+N  T      L    SD      D+ L+GGD +++ H E + ++  +  +   KK  I+LR        TL  S  S+ S+   W+VE+   +  R     GQW+S FRF+H     YL+ +  L V   K            +  + N +  L+  +   L     ++P   Y R+ H+ T TW+ +    +          D  E+    LK  T + +E          +AF +  VP   V   +  +    ++ + +   KK    T +Q+ R +   + + D ++            LD    KP+  RQK +R   I+  +  ++  PF  K                 A  + I R  + +L +  +    KN  Y AK+  + +      + +G+ I+  + I  LL NN+K+LE  I+ +EI  F++ LR N+  R+L+YL   CV N    P+TQ  I
Sbjct:    5 MSSFLYIGDIVSLYAEGSVNGFISTLGLVDDRCVVHPDAGDLANPPKKF--------RDCLFKVCPMNRYSAQKQFWKAKQAKQGNNTEAALLKKLQHAAEL----EQKQNESENRKLLGEIVKYSNVIQLLHIKSNKYLTVNKRLPALLEKNAMRVSLDCAGNEGSWFYIQPFWKLRSEGDNVVVGDKVVLMPVNA-GQPLHASNIELLDN--PGCKEVNAVNCNTSWK-VNLFMKFSDY----RDDVLKGGDVVRLFHAEQEKFLTCDEYE---KKQHIFLRT-------TLRQSATSATSSKALWEVEVVHHDPCRGGA--GQWNSLFRFKHLATGNYLAAEVKLPVHKRKWQAGEKIMYTLVSVPHGNDIASLFELDATTLQRADCLVPRNSYVRLRHLCTNTWVTSTSIPI----------DTEEERPVMLKIGTCQTKE--------DKEAFAIISVPLSEVRDLDFANDANKVLASTV---KKLEYGTITQNER-RFVTKLLEDLIFFVAGVANNGQEVLDVVVTKPNRERQKLMREQNILAQIFGILKAPFKDKAGEGSMLRLEDLGDQRYAPYKYILRLCYRVLRHSQQDYR-KNQEYIAKHFCVMQ------SQIGYDILAEDTITALLHNNRKLLEKHITAKEIETFVNLLRRNREPRFLDYLSDLCVSNTTAIPVTQELI 635          
BLAST of Inositol 1,4,5-trisphosphate receptor type 3 vs. Ensembl Xenopus
Match: sfi1 (SFI1 centrin binding protein [Source:Xenbase;Acc:XB-GENE-5749440])

HSP 1 Score: 134.035 bits (336), Expect = 3.025e-30
Identity = 180/694 (25.94%), Postives = 301/694 (43.37%), Query Frame = 2
Query:  164 MNDYLSYGDRICLYCEET-NGFINS-----NNSSSHYNELRIFSKQDKFNPENVSDIQEIIFEVVIQNRXXXXXXX-XXXXXDINNKSENLELKIQAEQAKATVISEENDNALENRRNLGKTVHYGDVIQLRHVYTRKYIHVNIAKTSSKDQNSMILNLQSHNLKSAQFKIVPRYKVKYEGEPVQFMDLVTFESLKAPSHYFHASDLYQIDNFFHGA----ALNLATEQSGFTLIKSASDTHIMEEDNFLRGGDYIQIIHKEIDGYIESEGIQGGMKKADIYLRIRKSDKFQTLTNSRLSS-SANTFWQVEI---EKVRLSTEIGQWSSNFRFRHATNRLYLS--VKKDLSVSMTK------------NATNPNTVFRLYPQNIDKL-----IIPYGRYFRMEHVLTGTWIHANKEQVYVKPNQSKYDDAAEKCLGNLKYETNELRELFCVHQRLYDDAFVVFKVPTEIVESFNLLSGYFPLIKNLIVDRKKAVPFTASQSYRYKLALEEIRDSLY------------LD---GKPHSLRQKHLRNLQIVDLLVELVLLPFHSKIDA--------------AFTEKIYRASFEILHNYMKGSSIKNSLYFAKYINLFEPKMLENNDLGHKII--EMIAELLRNNQKVLE-CISFQEIFPFIDNLRINQNFRYLEYLETFCVCNGE--PMTQNQI 2041
            M+ +L  GD + LY E + NGFI++     +    H +   + +   KF        ++ +F+V   NRY   K++         N +E   LK     A+     E+  N  ENR+ LG+ V Y +VIQL H+ + KY+ VN    +  ++N+M ++L     + + F I P +K++ EG+ V   D V    + A     HAS++  +DN   G     A+N  T      L    SD      D+ L+GGD +++ H E + ++  +  +   KK  I+LR        TL  S  S+ S+   W+VE+   +  R     GQW+S FRF+H     YL+  VK +L V   K            +  + N +  L+  +   L     ++P   Y R+ H+ T TW+ +    +          D  E+    LK  T + +E          +AF +  VP   V   +  +    ++ + +   KK    T +Q+ R +   + + D ++            LD    KP+  RQK +R   I+  +  ++  PF  K                 A  + I R  + +L +  +    KN  Y AK+  + +      + +G+ I+  + I  LL NN+K+LE  I+ +EI  F++ LR N+  R+L+YL   CV N    P+TQ  I
Sbjct:    5 MSSFLYIGDIVSLYAEGSVNGFISTLGLVDDRCVVHPDAGDLANPPKKF--------RDCLFKVCPMNRYSAQKQFWKAKQAKQGNNTEAALLKKLQHAAEL----EQKQNESENRKLLGEIVKYSNVIQLLHIKSNKYLTVNKRLPALLEKNAMRVSLDCAGNEGSWFYIQPFWKLRSEGDNVVVGDKVVLMPVNA-GQPLHASNIELLDN--PGCKEVNAVNCNTSWK-VNLFMKFSDY----RDDVLKGGDVVRLFHAEQEKFLTCDEYE---KKQHIFLRT-------TLRQSATSATSSKALWEVEVVHHDPCRGGA--GQWNSLFRFKHLATGNYLAAEVKGELPVHKRKWQAGEKIMYTLVSVPHGNDIASLFELDATTLQRADCLVPRNSYVRLRHLCTNTWVTSTSIPI----------DTEEERPVMLKIGTCQTKE--------DKEAFAIISVPLSEVRDLDFANDANKVLASTV---KKLEYGTITQNER-RFVTKLLEDLIFFVAGVANNGQEVLDVVVTKPNRERQKLMREQNILAQIFGILKAPFKDKAGEGSMLRLEDLGDQRYAPYKYILRLCYRVLRHSQQDYR-KNQEYIAKHFCVMQ------SQIGYDILAEDTITALLHNNRKLLEKHITAKEIETFVNLLRRNREPRFLDYLSDLCVSNTTAIPVTQELI 637          
BLAST of Inositol 1,4,5-trisphosphate receptor type 3 vs. Ensembl Xenopus
Match: sfi1 (SFI1 centrin binding protein [Source:Xenbase;Acc:XB-GENE-5749440])

HSP 1 Score: 128.257 bits (321), Expect = 1.745e-28
Identity = 178/701 (25.39%), Postives = 300/701 (42.80%), Query Frame = 2
Query:  164 MNDYLSYGDRICLYCEET-NGFINS-----NNSSSHYNELRIFSKQDKFNPENVSDIQEIIFEVVIQNRXXXXXXX-XXXXXDINNKSENLELKIQAEQAKATVISEENDNALENRRNLGKTVHYGDVIQLRHVYTRKYIHVNIAKTSSKDQNSMILNLQSHNLKSAQFKIVPRYKVKYEGEPVQFMDLVTFESLKAPSHYFHASDLYQIDNFFHGA----ALNLATEQSGFTLIKSASDTHIMEEDNFLRGGDYIQIIHKEIDGYIESEGIQGGMKKADIYLRIRKSDKFQTLTNSRLSS-SANTFWQVEI---EKVRLSTEIGQWSSNFRFRHATNRLYLSVK---------KDLSVSMTK------------NATNPNTVFRLYPQNIDKL-----IIPYGRYFRMEHVLTGTWIHANKEQVYVKPNQSKYDDAAEKCLGNLKYETNELRELFCVHQRLYDDAFVVFKVPTEIVESFNLLSGYFPLIKNLIVDRKKAVPFTASQSYRYKLALEEIRDSLY------------LD---GKPHSLRQKHLRNLQIVDLLVELVLLPFHSKIDA--------------AFTEKIYRASFEILHNYMKGSSIKNSLYFAKYINLFEPKMLENNDLGHKII--EMIAELLRNNQKVLE-CISFQEIFPFIDNLRINQNFRYLEYLETFCVCNGE--PMTQNQI 2041
            M+ +L  GD + LY E + NGFI++     +    H +   + +   KF        ++ +F+V   NRY   K++         N +E   LK     A+     E+  N  ENR+ LG+ V Y +VIQL H+ + KY+ VN    +  ++N+M ++L     + + F I P +K++ EG+ V   D V    + A     HAS++  +DN   G     A+N  T      L    SD      D+ L+GGD +++ H E + ++  +  +   KK  I+LR        TL  S  S+ S+   W+VE+   +  R     GQW+S FRF+H     YL+ +          +L V   K            +  + N +  L+  +   L     ++P   Y R+ H+ T TW+ +    +          D  E+    LK  T + +E          +AF +  VP   V   +  +    ++ + +   KK    T +Q+ R +   + + D ++            LD    KP+  RQK +R   I+  +  ++  PF  K                 A  + I R  + +L +  +    KN  Y AK+  + +      + +G+ I+  + I  LL NN+K+LE  I+ +EI  F++ LR N+  R+L+YL   CV N    P+TQ  I
Sbjct:    5 MSSFLYIGDIVSLYAEGSVNGFISTLGLVDDRCVVHPDAGDLANPPKKF--------RDCLFKVCPMNRYSAQKQFWKAKQAKQGNNTEAALLKKLQHAAEL----EQKQNESENRKLLGEIVKYSNVIQLLHIKSNKYLTVNKRLPALLEKNAMRVSLDCAGNEGSWFYIQPFWKLRSEGDNVVVGDKVVLMPVNA-GQPLHASNIELLDN--PGCKEVNAVNCNTSWK-VNLFMKFSDY----RDDVLKGGDVVRLFHAEQEKFLTCDEYE---KKQHIFLRT-------TLRQSATSATSSKALWEVEVVHHDPCRGGA--GQWNSLFRFKHLATGNYLAAEINPDYRDREGELPVHKRKWQAGEKIMYTLVSVPHGNDIASLFELDATTLQRADCLVPRNSYVRLRHLCTNTWVTSTSIPI----------DTEEERPVMLKIGTCQTKE--------DKEAFAIISVPLSEVRDLDFANDANKVLASTV---KKLEYGTITQNER-RFVTKLLEDLIFFVAGVANNGQEVLDVVVTKPNRERQKLMREQNILAQIFGILKAPFKDKAGEGSMLRLEDLGDQRYAPYKYILRLCYRVLRHSQQDYR-KNQEYIAKHFCVMQ------SQIGYDILAEDTITALLHNNRKLLEKHITAKEIETFVNLLRRNREPRFLDYLSDLCVSNTTAIPVTQELI 644          
BLAST of Inositol 1,4,5-trisphosphate receptor type 3 vs. Ensembl Xenopus
Match: sfi1 (SFI1 centrin binding protein [Source:Xenbase;Acc:XB-GENE-5749440])

HSP 1 Score: 126.716 bits (317), Expect = 4.625e-28
Identity = 178/706 (25.21%), Postives = 297/706 (42.07%), Query Frame = 2
Query:  164 MNDYLSYGDRICLYCEET-NGFINS-----NNSSSHYNELRIFSKQDKFNPENVSDIQEIIFEVVIQNRXXXXXX-XXXXXXDINNKSENLELKIQAEQAKATVISEENDNALENRRNLGKTVHYGDVIQLRHVYTRKYIHVNIAKTSSKDQNSMILNLQSHNLKSAQFKIVPRYKVKYEGEPVQFMDLVTFESLKAPSHYFHASDLYQIDNFFHGA----ALNLATEQSGFTLIKSASDTHIMEEDNFLRGGDYIQIIHKEIDGYIESEGIQGGMKKADIYLRIRKSDKFQTLTNSRLSS-SANTFWQVEI---EKVRLSTEIGQWSSNFRFRHATNRLYLSVK--------------KDLSVSMTKNATNPNTVFRL--YPQNID---------------KLIIPYGRYFRMEHVLTGTWIHANKEQVYVKPNQSKYDDAAEKCLGNLKYETNELRELFCVHQRLYDDAFVVFKVPTEIVESFNLLSGYFPLIKNLIVDRKKAVPFTASQSYRYKLALEEIRDSLY------------LD---GKPHSLRQKHLRNLQIVDLLVELVLLPFHSKIDA--------------AFTEKIYRASFEILHNYMKGSSIKNSLYFAKYINLFEPKMLENNDLGHKII--EMIAELLRNNQKVLE-CISFQEIFPFIDNLRINQNFRYLEYLETFCVCNGE--PMTQNQI 2041
            M+ +L  GD + LY E + NGFI++     +    H +   + +   KF        ++ +F+V   NRY   K+ +        N +E   LK     A+     E+  N  ENR+ LG+ V Y +VIQL H+ + KY+ VN    +  ++N+M ++L     + + F I P +K++ EG+ V   D V    + A     HAS++  +DN   G     A+N  T      L    SD      D+ L+GGD +++ H E + ++  +  +   KK  I+LR        TL  S  S+ S+   W+VE+   +  R     GQW+S FRF+H     YL+ +               +L V   K       ++ L   P   D                 ++P   Y R+ H+ T TW+ +    +          D  E+    LK  T + +E          +AF +  VP   V   +  +    ++ + +   KK    T +Q+ R +   + + D ++            LD    KP+  RQK +R   I+  +  ++  PF  K                 A  + I R  + +L +  +    KN  Y AK+  + +      + +G+ I+  + I  LL NN+K+LE  I+ +EI  F++ LR N+  R+L+YL   CV N    P+TQ  I
Sbjct:    5 MSSFLYIGDIVSLYAEGSVNGFISTLGLVDDRCVVHPDAGDLANPPKKF--------RDCLFKVCPMNRYSAQKQFWKAKQAKQGNNTEAALLKKLQHAAEL----EQKQNESENRKLLGEIVKYSNVIQLLHIKSNKYLTVNKRLPALLEKNAMRVSLDCAGNEGSWFYIQPFWKLRSEGDNVVVGDKVVLMPVNA-GQPLHASNIELLDN--PGCKEVNAVNCNTSWK-VNLFMKFSDY----RDDVLKGGDVVRLFHAEQEKFLTCDEYE---KKQHIFLRT-------TLRQSATSATSSKALWEVEVVHHDPCRGGA--GQWNSLFRFKHLATGNYLAAEINPDYRDVGDPRATGELPVHKRKWQAGEKIMYTLVSVPHGNDIASLFELDATTLQRADCLVPRNSYVRLRHLCTNTWVTSTSIPI----------DTEEERPVMLKIGTCQTKE--------DKEAFAIISVPLSEVRDLDFANDANKVLASTV---KKLEYGTITQNER-RFVTKLLEDLIFFVAGVANNGQEVLDVVVTKPNRERQKLMREQNILAQIFGILKAPFKDKAGEGSMLRLEDLGDQRYAPYKYILRLCYRVLRHSQQDYR-KNQEYIAKHFCVMQ------SQIGYDILAEDTITALLHNNRKLLEKHITAKEIETFVNLLRRNREPRFLDYLSDLCVSNTTAIPVTQELI 649          
BLAST of Inositol 1,4,5-trisphosphate receptor type 3 vs. Ensembl Mouse
Match: Itpr1 (inositol 1,4,5-trisphosphate receptor 1 [Source:MGI Symbol;Acc:MGI:96623])

HSP 1 Score: 133.265 bits (334), Expect = 3.936e-30
Identity = 222/959 (23.15%), Postives = 399/959 (41.61%), Query Frame = 2
Query:  164 MNDYLSYGDRICLYCE-ETNGFINSNNSSSHYNELRIFSKQDKFNPENVSDI-------QEIIFEVVIQNRXXXXXXXXXXXXDINNKSENLELKIQAEQAKATVISEENDNALENRRNLGKTVHYGDVIQLRHVYTRKYIHVNIAKTSSKDQNSMILNLQSHNLKSAQFKIVPRYKVKYEGEPVQFMDLVTFESLKAPSHYFHASDLYQIDNFFHGAALNLATEQS-GFTLIKSASDTHIMEEDNFLRGGDYIQIIHKEIDGYIESEGIQGGMKKADIYLRIRKSDKFQTLTNSRLSSSANTFWQVEI-EKVRLSTEIGQWSSNFRFRHATNRLYLSVK-------------------KDLSVSMTKNA--------------TNPNTVFRLYPQNI--DKLIIPYGRYFRMEHVLTGTWIHANKEQVYVKPNQSKYDDAAEKCLGNLKYETNELRELFCVHQRLYDDAFVVFKVPTEIVESFNLLSGYFPLIKNLIVDRKKAVPFTASQSYRYKLA--LEEI-----------RDSL-YLDGKPHSLRQKHLRNLQIVDLLVELVLLPFHSKIDA-------------AFTEKIYRASFEILHNYMKGSSIKNSLYFAKYINLFEPKMLENNDLGHKII--EMIAELLRNNQKVLE-CISFQEIFPFIDNLRINQNFRYLEYLETFCVCNGE--PMTQNQIKIAVKWLSEDQRGVFLTDR-------GQNLNLESNVIYIKTKLDSNWMKLHEFLDITAQIDQENNPLYHQDNKD----------YFLKQMDLLLALCYGRNQYCTNLIINKLNYISWEQCFAAINSPMIPPYMKTKYFEIIQTMFIDIGRNYAVIESP-KFNFIFNQIQGDSSVAVECMFPTPSESVTIK-IFKDLSEWIYNFLEST--PRMISSNKDFNYLIRIVFITINKLIQYGYYDSPSLDRICKSLLKLLN 2746
            M+ +L  GD   LY E  TNGFI++         L +   +    PE   D+       ++ +F++   NRY   K++ K  K   N + +  L  +   A      E+  N  ENR+ LG  + YG+VIQL H+ + KY+ VN    +  ++N+M + L     + + F I P YK++  G+ V   D V    + A     HAS    +DN       ++    S    L    SD     +D+ L+GGD +++ H E + ++  +  +   KK  ++LR   +   Q+ T++   +S+   W+VE+ +        G W+S FRF+H     YL+ +                   +D S S  +NA               + +++F L P  +     ++P   Y R+ H+ T TW+H+    +          D  E+    LK  T+ L+E          +AF +  V    V   +  +    ++ ++    +K    T +Q+ R  +   LE++           +D L  +  KP+  RQK +R   I+  + +L+  PF    D              A    I R  + +L +  +    KN  Y AK     + +      +G+ ++  + I  LL NN+K+LE  I+  EI  F+  +R N+  R+L+YL   CV   +  P+TQ  I  AV  L+     + +  +        + ++   N +      +  W+    + D   +I  ++     QD K+          Y+  Q++L   +C  R     N I  +L+     +C +  N   +P  ++  +  ++  M +D  R+     +P K+  ++++I   S +A++    + +    IK  F    E++  +L      R   S+K+ N L   V      LI +G+Y+   L R+ K LL +L+
Sbjct:    5 MSSFLHIGDICSLYAEGSTNGFIST---------LGLVDDRCVVQPE-AGDLNNPPKKFRDCLFKLCPMNRYSAQKQFWKAAKPGANSTTDAVLLNKLHHAADL---EKKQNETENRKLLGTVIQYGNVIQLLHLKSNKYLTVNKRLPALLEKNAMRVTLDEAGNEGSWFYIQPFYKLRSIGDSVVIGDKVVLNPVNA-GQPLHASSHQLVDNPGCNEVNSVNCNTSWKIVLFMKWSDN----KDDILKGGDVVRLFHAEQEKFLTCDEHR---KKQHVFLR---TTGRQSATSA---TSSKALWEVEVVQHDPCRGGAGYWNSLFRFKHLATGHYLAAEVDPDFEEECLEFQPSVDPDQDASRSRLRNAQEKMVYSLVSVPEGNDISSIFELDPTTLRGGDSLVPRNSYVRLRHLCTNTWVHSTNIPI----------DKEEEKPVMLKIGTSPLKE--------DKEAFAIVPVSPAEVRDLDFANDASKVLGSIAGKLEKG---TITQNERRSVTKLLEDLVYFVTGGTNSGQDVLEVVFSKPNRERQKLMREQNILKQIFKLLQAPFTDCGDGPMLRLEELGDQRHAPFRHICRLCYRVLRHSQQDYR-KNQEYIAKQFGFMQKQ------IGYDVLAEDTITALLHNNRKLLEKHITAAEIDTFVSLVRKNREPRFLDYLSDLCVSMNKSIPVTQELICKAV--LNPTNADILIETKLVLSRFEFEGVSTGENALEAGEDEEEVWLF---WRDSNKEIRSKSVRELAQDAKEGQKEDRDILSYYRYQLNLFARMCLDRQYLAINEISGQLDVDLILRCMSDEN---LPYDLRASFCRLMLHMHVD--RDPQEQVTPVKYARLWSEIP--SEIAIDDYDSSGTSKDEIKERFAQTMEFVEEYLRDVVCQRFPFSDKEKNKLTFEVVNLARNLIYFGFYNFSDLLRLTKILLAILD 896          

HSP 2 Score: 82.8037 bits (203), Expect = 8.529e-15
Identity = 48/147 (32.65%), Postives = 75/147 (51.02%), Query Frame = 3
Query: 7584 VDTFSELRDLKYKTEKDMKETCFICSRAGHDFDQSSSSFEHHVVYEHNMWAYLFYFLHLKEIKINDYFHLDLYVANMLKRENYDFFPINCALSLT-----AEQEKYSRIDEISRNVKIIVSN----------RQNEEREKLRRTNLF 7979
            +DTF++LR  K K E+ +K TCFIC      FD  + +FE H+  EHNMW YL + + +K     +Y   + YVA M++  N D+FP   A+SL       EQ +   + E   +   +V+N          +  E+R++ +R  L 
Sbjct: 2589 IDTFADLRSEKQKKEEILKTTCFICGLERDKFDNKTVTFEEHIKEEHNMWHYLCFIVLVKVKDSTEYTGPESYVAEMIRERNLDWFPRMRAMSLVSSDSEGEQNELRNLQEKLESTMKLVTNLSGQLSELKDQMTEQRKQKQRIGLL 2735          
BLAST of Inositol 1,4,5-trisphosphate receptor type 3 vs. Ensembl Mouse
Match: Itpr1 (inositol 1,4,5-trisphosphate receptor 1 [Source:MGI Symbol;Acc:MGI:96623])

HSP 1 Score: 133.265 bits (334), Expect = 4.104e-30
Identity = 222/959 (23.15%), Postives = 399/959 (41.61%), Query Frame = 2
Query:  164 MNDYLSYGDRICLYCE-ETNGFINSNNSSSHYNELRIFSKQDKFNPENVSDI-------QEIIFEVVIQNRXXXXXXXXXXXXDINNKSENLELKIQAEQAKATVISEENDNALENRRNLGKTVHYGDVIQLRHVYTRKYIHVNIAKTSSKDQNSMILNLQSHNLKSAQFKIVPRYKVKYEGEPVQFMDLVTFESLKAPSHYFHASDLYQIDNFFHGAALNLATEQS-GFTLIKSASDTHIMEEDNFLRGGDYIQIIHKEIDGYIESEGIQGGMKKADIYLRIRKSDKFQTLTNSRLSSSANTFWQVEI-EKVRLSTEIGQWSSNFRFRHATNRLYLSVK-------------------KDLSVSMTKNA--------------TNPNTVFRLYPQNI--DKLIIPYGRYFRMEHVLTGTWIHANKEQVYVKPNQSKYDDAAEKCLGNLKYETNELRELFCVHQRLYDDAFVVFKVPTEIVESFNLLSGYFPLIKNLIVDRKKAVPFTASQSYRYKLA--LEEI-----------RDSL-YLDGKPHSLRQKHLRNLQIVDLLVELVLLPFHSKIDA-------------AFTEKIYRASFEILHNYMKGSSIKNSLYFAKYINLFEPKMLENNDLGHKII--EMIAELLRNNQKVLE-CISFQEIFPFIDNLRINQNFRYLEYLETFCVCNGE--PMTQNQIKIAVKWLSEDQRGVFLTDR-------GQNLNLESNVIYIKTKLDSNWMKLHEFLDITAQIDQENNPLYHQDNKD----------YFLKQMDLLLALCYGRNQYCTNLIINKLNYISWEQCFAAINSPMIPPYMKTKYFEIIQTMFIDIGRNYAVIESP-KFNFIFNQIQGDSSVAVECMFPTPSESVTIK-IFKDLSEWIYNFLEST--PRMISSNKDFNYLIRIVFITINKLIQYGYYDSPSLDRICKSLLKLLN 2746
            M+ +L  GD   LY E  TNGFI++         L +   +    PE   D+       ++ +F++   NRY   K++ K  K   N + +  L  +   A      E+  N  ENR+ LG  + YG+VIQL H+ + KY+ VN    +  ++N+M + L     + + F I P YK++  G+ V   D V    + A     HAS    +DN       ++    S    L    SD     +D+ L+GGD +++ H E + ++  +  +   KK  ++LR   +   Q+ T++   +S+   W+VE+ +        G W+S FRF+H     YL+ +                   +D S S  +NA               + +++F L P  +     ++P   Y R+ H+ T TW+H+    +          D  E+    LK  T+ L+E          +AF +  V    V   +  +    ++ ++    +K    T +Q+ R  +   LE++           +D L  +  KP+  RQK +R   I+  + +L+  PF    D              A    I R  + +L +  +    KN  Y AK     + +      +G+ ++  + I  LL NN+K+LE  I+  EI  F+  +R N+  R+L+YL   CV   +  P+TQ  I  AV  L+     + +  +        + ++   N +      +  W+    + D   +I  ++     QD K+          Y+  Q++L   +C  R     N I  +L+     +C +  N   +P  ++  +  ++  M +D  R+     +P K+  ++++I   S +A++    + +    IK  F    E++  +L      R   S+K+ N L   V      LI +G+Y+   L R+ K LL +L+
Sbjct:    5 MSSFLHIGDICSLYAEGSTNGFIST---------LGLVDDRCVVQPE-AGDLNNPPKKFRDCLFKLCPMNRYSAQKQFWKAAKPGANSTTDAVLLNKLHHAADL---EKKQNETENRKLLGTVIQYGNVIQLLHLKSNKYLTVNKRLPALLEKNAMRVTLDEAGNEGSWFYIQPFYKLRSIGDSVVIGDKVVLNPVNA-GQPLHASSHQLVDNPGCNEVNSVNCNTSWKIVLFMKWSDN----KDDILKGGDVVRLFHAEQEKFLTCDEHR---KKQHVFLR---TTGRQSATSA---TSSKALWEVEVVQHDPCRGGAGYWNSLFRFKHLATGHYLAAEVDPDFEEECLEFQPSVDPDQDASRSRLRNAQEKMVYSLVSVPEGNDISSIFELDPTTLRGGDSLVPRNSYVRLRHLCTNTWVHSTNIPI----------DKEEEKPVMLKIGTSPLKE--------DKEAFAIVPVSPAEVRDLDFANDASKVLGSIAGKLEKG---TITQNERRSVTKLLEDLVYFVTGGTNSGQDVLEVVFSKPNRERQKLMREQNILKQIFKLLQAPFTDCGDGPMLRLEELGDQRHAPFRHICRLCYRVLRHSQQDYR-KNQEYIAKQFGFMQKQ------IGYDVLAEDTITALLHNNRKLLEKHITAAEIDTFVSLVRKNREPRFLDYLSDLCVSMNKSIPVTQELICKAV--LNPTNADILIETKLVLSRFEFEGVSTGENALEAGEDEEEVWLF---WRDSNKEIRSKSVRELAQDAKEGQKEDRDILSYYRYQLNLFARMCLDRQYLAINEISGQLDVDLILRCMSDEN---LPYDLRASFCRLMLHMHVD--RDPQEQVTPVKYARLWSEIP--SEIAIDDYDSSGTSKDEIKERFAQTMEFVEEYLRDVVCQRFPFSDKEKNKLTFEVVNLARNLIYFGFYNFSDLLRLTKILLAILD 896          

HSP 2 Score: 82.8037 bits (203), Expect = 8.673e-15
Identity = 48/147 (32.65%), Postives = 75/147 (51.02%), Query Frame = 3
Query: 7584 VDTFSELRDLKYKTEKDMKETCFICSRAGHDFDQSSSSFEHHVVYEHNMWAYLFYFLHLKEIKINDYFHLDLYVANMLKRENYDFFPINCALSLT-----AEQEKYSRIDEISRNVKIIVSN----------RQNEEREKLRRTNLF 7979
            +DTF++LR  K K E+ +K TCFIC      FD  + +FE H+  EHNMW YL + + +K     +Y   + YVA M++  N D+FP   A+SL       EQ +   + E   +   +V+N          +  E+R++ +R  L 
Sbjct: 2588 IDTFADLRSEKQKKEEILKTTCFICGLERDKFDNKTVTFEEHIKEEHNMWHYLCFIVLVKVKDSTEYTGPESYVAEMIRERNLDWFPRMRAMSLVSSDSEGEQNELRNLQEKLESTMKLVTNLSGQLSELKDQMTEQRKQKQRIGLL 2734          
BLAST of Inositol 1,4,5-trisphosphate receptor type 3 vs. Ensembl Mouse
Match: Itpr2 (inositol 1,4,5-triphosphate receptor 2 [Source:MGI Symbol;Acc:MGI:99418])

HSP 1 Score: 119.783 bits (299), Expect = 5.494e-26
Identity = 172/708 (24.29%), Postives = 298/708 (42.09%), Query Frame = 2
Query:  164 MNDYLSYGDRICLYCEET-NGFINS-----NNSSSHYNELRIFSKQDKFNPENVSDIQEIIFEVVIQNRXXXXXXX-XXXXXDINNKSENLELKIQAEQAKATVISEENDNALENRRNLGKTVHYGDVIQLRHVYTRKYIHVNIAKTSSKDQNSMILNLQSHNLKSAQFKIVPRYKVKYEGEPVQFMDLVTFESLKAPSHYFHASDLYQIDNFFHGA----ALNLATEQSGFTLIKSASDTHIMEEDNFLRGGDYIQIIHKEIDGYIESEGIQGGMKKADIYLRIRKSDKFQTLTNSRLSS-SANTFWQVEI---EKVRLSTEIGQWSSNFRFRHATNRLYLSVK---------------KDLSVSMTK--------------NATNPNTVFRLYPQNIDKL-----IIPYGRYFRMEHVLTGTWIHANKEQVYVKPNQSKYDDAAEKCLGNLKYETNELRELFCVHQRLYDDAFVVFKVPTEIVESFNLLSGYFPLIKNLIVDRKKAVPFTASQSYRYKLALEEIRDSLY------------LD---GKPHSLRQKHLRNLQIVDLLVELVLLPFHSKIDAAFTEKI----------YRASFEILHNYMKGSS---IKNSLYFAKYINLFEPKMLENNDLGHKII--EMIAELLRNNQKVLE-CISFQEIFPFIDNLRINQNFRYLEYLETFCVCNGE--PMTQNQI 2041
            M+ +L  GD + LY E + NGFI++     +    H     + +   KF        ++ +F+V   NRY   K+Y         N +E   LK     A+     E+  N  ENR+ LG+ V Y +VIQL H+ + KY+ VN    +  ++N+M ++L +   + + F I P +K++ EG+ +   D V    + A     HAS++  +DN   G     A+N  T       +K +S       ++ L+GGD +++ H E + ++  +  +   KK  I+LR        TL  S  S+ S+   W++E+   +  R     GQW+S FRF+H     YL+ +               KD  +   K              +  + N +  L+  +   L     ++P   Y R+ H+ T TW+ +    +          D  E+    LK  T + +E          +AF +  VP   V   +  +    ++   +   KK    + +Q+ R +   + + D ++            LD    KP+  RQK +R   I+  +  ++  PF  K       ++          Y+    + +  ++ S     KN  Y AK   + + +      +G+ I+  + I  LL NN+K+LE  I+ +EI  F+  LR N+  R+L+YL   CV N    P+TQ  I
Sbjct:    5 MSSFLYIGDIVSLYAEGSVNGFISTLGLVDDRCVVHPEAGDLANPPKKF--------RDCLFKVCPMNRYSAQKQYWKAKQAKQGNHTEAALLKKLQHAAEL----EQKQNESENRKLLGEIVKYSNVIQLLHIKSNKYLTVNKRLPALLEKNAMRVSLDAAGNEGSWFYIHPFWKLRSEGDNIVVGDKVVLMPVNA-GQPLHASNVELLDN--PGCKEVNAVNCNTSWKITLFMKFSS-----YREDVLKGGDVVRLFHAEQEKFLTCDDYE---KKQHIFLRT-------TLRQSATSATSSKALWEIEVVHHDPCRGGA--GQWNSLFRFKHLATGNYLAAELNPDYRDAQNEGKNVKDGEIPTPKKKRQAGEKIMYTLVSVPHGNDIASLFELDATTLQRADCLVPRNSYVRLRHLCTNTWVTSTTIPI----------DTEEERPVMLKIGTCQTKE--------DKEAFAIVCVPLSEVRDLDFANDANKVLATTV---KKLENGSITQNER-RFVTKLLEDLIFFVADVTNNGQDVLDVVITKPNRERQKLMREQNILAQVFGILKAPFKEKAGEGSMLRLEDLGDQRYAPYKYVLRLCYRVLRHSQQDYRKNQEYIAKNFCVMQSQ------IGYDILAEDTITALLHNNRKLLEKHITAKEIETFVSLLRRNREPRFLDYLSDLCVSNSTAIPVTQELI 652          

HSP 2 Score: 84.3445 bits (207), Expect = 2.605e-15
Identity = 46/112 (41.07%), Postives = 67/112 (59.82%), Query Frame = 3
Query: 7584 VDTFSELRDLKYKTEKDMKETCFICSRAGHDFDQSSSSFEHHVVYEHNMWAYLFYFLHLKEIKINDYFHLDLYVANMLKRENYDFFPINCALSLTAEQEKYSRIDEISRNVK 7919
            +DTF++LR  K K E+ +K TCFIC      FD  + SFE H+  EHNMW YL++ + +K     +Y   + YVA M+  +N D+FP   A+SL +  E  S  +EI RN++
Sbjct: 2541 IDTFADLRSEKQKKEEILKTTCFICGLERDKFDNKTVSFEEHIKSEHNMWHYLYFIVLVKVKDPTEYTGPESYVAQMITEKNLDWFPRMRAMSLVS-NEGDSEQNEI-RNLQ 2650          
BLAST of Inositol 1,4,5-trisphosphate receptor type 3 vs. Ensembl Mouse
Match: Itpr3 (inositol 1,4,5-triphosphate receptor 3 [Source:MGI Symbol;Acc:MGI:96624])

HSP 1 Score: 111.309 bits (277), Expect = 1.754e-23
Identity = 165/698 (23.64%), Postives = 294/698 (42.12%), Query Frame = 2
Query:  164 MNDYLSYGDRICLYCEET-NGFINSNNSSSHYNELRIFSKQDKFNPENVSDIQEIIFEVVIQNRXXXXXXXXXXXXDINNKSENLELKI-QAEQAKATVISEENDNALENRRNLGKTVHYGDVIQLRHVYTRKYIHVNIAKTSSKDQNSMILNLQSHNLKSAQFKIVPRYKVKYEGEPVQFMDLVTFESLKAPSHYFHASDLYQIDNFFHGAALNLATEQSGFTLIKSASDTHIMEEDNFLRGGDYIQIIHKEIDGYIESEGIQGGMKKADIYLRIRKSDKFQTLTNSRLSS-SANTFWQVEI---EKVRLSTEIGQWSSNFRFRHATNRLYLSVKKDLS----VSMTKNA---------------------------TNPNTVFRLYPQNIDKL--IIPYGRYFRMEHVLTGTWIHANKEQVYVKPNQSKYDDAAEKCLGNLKYETNELRELFCVHQRLYDDAFVVFKVPTEIVESFNLLSGYFPLIKNLIVDRKKAVPFTASQSYRYKLALEEIRDSLY------------LD---GKPHSLRQKHLRNLQIVDLLVELVLLPFHSKIDAAFTEKI----------YRASFEILHNYMKGSS---IKNSLYFAKYINLFEPKMLENNDLGHKII--EMIAELLRNNQKVLE-CISFQEIFPFIDNLRINQNFRYLEYLETFCVCN--GEPMTQNQI 2041
            M+ +L  GD + LY E + NGFI++         +   +  D  NP      ++ +F+V   NRY   K+Y K  +   +K +  ++ + Q  Q  A +  ++ND   EN++  G  V YG VIQL H+ + KY+ VN    +  ++N+M + L +   + +   I P +K++  G+ V   D V    + A     HAS+ Y++ +      +N     + + +         +EE   L+GGD +++ H E + ++  +  +G   K  ++LR        TL  S  S+ S+N  W+VE+   +  R     G W+  +RF+H     YL+ +++ S    VS  K A                            +  ++F L P  + K    +P   Y R+ H+ T TWI +    + V+  +          LG     T E +E           AF +  VP   +   +  +    ++ + +   K    F +    R+ + L  + D ++            LD    KP+  RQK +R   I+  +  ++  PF  K       ++          Y+  F + +  ++ S     KN  + AK   + + +      +G+ I+  + I  LL NN+K+LE  I+  E+  F+  +R N+  R+L+YL   CV N    P+TQ  I
Sbjct:    4 MSSFLHIGDIVSLYAEGSVNGFISTLGLVDDRCVVEP-AAGDLDNPPK--KFRDCLFKVCPMNRYSAQKQYWKAKQTKQDKEKIADVVLLQKLQHAAQMEQKQNDT--ENKKVHGDVVKYGSVIQLLHMKSNKYLTVNKRLPALLEKNAMRVTLDATGNEGSWLFIQPFWKLRSNGDNVVVGDKVILNPVNA-GQPLHASN-YELSDNAGCKEVNSVNCNTSWKINLFMQFRDHLEE--VLKGGDVVRLFHAEQEKFLTCDEYRG---KLQVFLRT-------TLRQSATSATSSNALWEVEVVHHDPCRGGA--GHWNGLYRFKHLATGNYLAAEENPSYKGDVSDPKAAGLGAQGRTGRRNAGEKIKYRLVAVPHGNDIASLFELDPTTLQKTDSFVPRNSYVRLRHLCTNTWIQSTNAPIDVEEER-----PIRLMLGTCP--TKEDKE-----------AFAIVSVPVSEIRDLDFANDASSMLASAV--EKLNEGFISQNDRRFVIQL--LEDLVFFVSDVPNNGQNVLDIMVTKPNRERQKLMREQNILKQIFGILKAPFRDKGGEGPLVRLEELSDQKNAPYQYMFRLCYRVLRHSQEDYRKNQEHIAKQFGMMQSQ------IGYDILAEDTITALLHNNRKLLEKHITKTEVETFVSLVRKNREPRFLDYLSDLCVSNRIAIPVTQELI 652          

HSP 2 Score: 87.4261 bits (215), Expect = 2.982e-16
Identity = 48/134 (35.82%), Postives = 78/134 (58.21%), Query Frame = 3
Query: 7584 VDTFSELRDLKYKTEKDMKETCFICSRAGHDFDQSSSSFEHHVVYEHNMWAYLFYFLHLKEIKINDYFHLDLYVANMLKRENYDFFPINCALSLT-----AEQEKYSRIDE-ISRNVKII--VSNRQNEEREKL 7961
            +DTF++LR  K K E+ +K TCFIC      FD  + SFE H+  EHNMW YL++ + ++     DY   + YVA M+K +N D+FP   A+SL       EQ +   + E +   +K++  ++++ NE +E++
Sbjct: 2516 IDTFADLRSEKQKKEEILKTTCFICGLERDKFDNKTVSFEEHIKLEHNMWNYLYFIVLVRVKNKTDYTGPESYVAQMIKNKNLDWFPRMRAMSLVSGEGEGEQNEIRILQEKLGSTMKLVSHLTSQLNELKEQM 2649          
BLAST of Inositol 1,4,5-trisphosphate receptor type 3 vs. Ensembl Mouse
Match: Itpr2 (inositol 1,4,5-triphosphate receptor 2 [Source:MGI Symbol;Acc:MGI:99418])

HSP 1 Score: 104.375 bits (259), Expect = 2.305e-21
Identity = 164/704 (23.30%), Postives = 285/704 (40.48%), Query Frame = 2
Query:  164 MNDYLSYGDRICLYCEET-NGFINS-----NNSSSHYNELRIFSKQDKFNPENVSDIQEIIFEVVIQNRXXXXXXX-XXXXXDINNKSENLELKIQAEQAKATVISEENDNALENRRNLGKTVHYGDVIQLRHVYTRKYIHVNIAKTSSKDQNSMILNLQSHNLKSAQFKIVPRYKVKYEGEPVQFMDLVTFESLKAPSHYFHASDLYQIDNFFHGAALNLATEQSGFTLIKSASDTHIMEEDNFLRGGDYIQIIHKEIDGYIESEGIQGGMKKADIYLRIRKSDKFQTLTNSRLSS-SANTFWQVEI---EKVRLSTEIGQWSSNFRFRHATNRLYLSVK---------------KDLSVSMTK--------------NATNPNTVFRLYPQNIDKL-----IIPYGRYFRMEHVLTGTWIHANKEQVYVKPNQSKYDDAAEKCLGNLKYETNELRELFCVHQRLYDDAFVVFKVPTEIVESFNLLSGYFPLIKNLIVDRKKAVPFTASQSYRYKLALEEIRDSLY------------LD---GKPHSLRQKHLRNLQIVDLLVELVLLPFHSKIDAAFTEKI----------YRASFEILHNYMKGSS---IKNSLYFAKYINLFEPKMLENNDLGHKII--EMIAELLRNNQKVLE-CISFQEIFPFIDNLRINQNFRYLEYLETFCVCNGE--PMTQNQI 2041
            M+ +L  GD + LY E + NGFI++     +    H     + +   KF        ++ +F+V   NRY   K+Y         N +E   LK     A+     E+  N  ENR+ LG+ V Y +VIQL H+ + KY+ VN    +  ++N+M ++L +   + + F I P +K++ EG+ V                                 A+N  T       +K +S       ++ L+GGD +++ H E + ++  +  +   KK  I+LR        TL  S  S+ S+   W++E+   +  R     GQW+S FRF+H     YL+ +               KD  +   K              +  + N +  L+  +   L     ++P   Y R+ H+ T TW+ +    +          D  E+    LK  T + +E          +AF +  VP   V   +  +    ++   +   KK    + +Q+ R +   + + D ++            LD    KP+  RQK +R   I+  +  ++  PF  K       ++          Y+    + +  ++ S     KN  Y AK   + + +      +G+ I+  + I  LL NN+K+LE  I+ +EI  F+  LR N+  R+L+YL   CV N    P+TQ  I
Sbjct:    5 MSSFLYIGDIVSLYAEGSVNGFISTLGLVDDRCVVHPEAGDLANPPKKF--------RDCLFKVCPMNRYSAQKQYWKAKQAKQGNHTEAALLKKLQHAAEL----EQKQNESENRKLLGEIVKYSNVIQLLHIKSNKYLTVNKRLPALLEKNAMRVSLDAAGNEGSWFYIHPFWKLRSEGDNVN--------------------------------AVNCNTSWKITLFMKFSS-----YREDVLKGGDVVRLFHAEQEKFLTCDDYE---KKQHIFLRT-------TLRQSATSATSSKALWEIEVVHHDPCRGGA--GQWNSLFRFKHLATGNYLAAELNPDYRDAQNEGKNVKDGEIPTPKKKRQAGEKIMYTLVSVPHGNDIASLFELDATTLQRADCLVPRNSYVRLRHLCTNTWVTSTTIPI----------DTEEERPVMLKIGTCQTKE--------DKEAFAIVCVPLSEVRDLDFANDANKVLATTV---KKLENGSITQNER-RFVTKLLEDLIFFVADVTNNGQDVLDVVITKPNRERQKLMREQNILAQVFGILKAPFKEKAGEGSMLRLEDLGDQRYAPYKYVLRLCYRVLRHSQQDYRKNQEYIAKNFCVMQSQ------IGYDILAEDTITALLHNNRKLLEKHITAKEIETFVSLLRRNREPRFLDYLSDLCVSNSTAIPVTQELI 619          

HSP 2 Score: 84.3445 bits (207), Expect = 2.827e-15
Identity = 46/112 (41.07%), Postives = 67/112 (59.82%), Query Frame = 3
Query: 7584 VDTFSELRDLKYKTEKDMKETCFICSRAGHDFDQSSSSFEHHVVYEHNMWAYLFYFLHLKEIKINDYFHLDLYVANMLKRENYDFFPINCALSLTAEQEKYSRIDEISRNVK 7919
            +DTF++LR  K K E+ +K TCFIC      FD  + SFE H+  EHNMW YL++ + +K     +Y   + YVA M+  +N D+FP   A+SL +  E  S  +EI RN++
Sbjct: 2508 IDTFADLRSEKQKKEEILKTTCFICGLERDKFDNKTVSFEEHIKSEHNMWHYLYFIVLVKVKDPTEYTGPESYVAQMITEKNLDWFPRMRAMSLVS-NEGDSEQNEI-RNLQ 2617          
BLAST of Inositol 1,4,5-trisphosphate receptor type 3 vs. UniProt/SwissProt
Match: sp|P11881|ITPR1_MOUSE (Inositol 1,4,5-trisphosphate receptor type 1 OS=Mus musculus OX=10090 GN=Itpr1 PE=1 SV=2)

HSP 1 Score: 133.265 bits (334), Expect = 2.753e-29
Identity = 222/959 (23.15%), Postives = 399/959 (41.61%), Query Frame = 2
Query:  164 MNDYLSYGDRICLYCE-ETNGFINSNNSSSHYNELRIFSKQDKFNPENVSDI-------QEIIFEVVIQNRXXXXXXXXXXXXDINNKSENLELKIQAEQAKATVISEENDNALENRRNLGKTVHYGDVIQLRHVYTRKYIHVNIAKTSSKDQNSMILNLQSHNLKSAQFKIVPRYKVKYEGEPVQFMDLVTFESLKAPSHYFHASDLYQIDNFFHGAALNLATEQS-GFTLIKSASDTHIMEEDNFLRGGDYIQIIHKEIDGYIESEGIQGGMKKADIYLRIRKSDKFQTLTNSRLSSSANTFWQVEI-EKVRLSTEIGQWSSNFRFRHATNRLYLSVK-------------------KDLSVSMTKNA--------------TNPNTVFRLYPQNI--DKLIIPYGRYFRMEHVLTGTWIHANKEQVYVKPNQSKYDDAAEKCLGNLKYETNELRELFCVHQRLYDDAFVVFKVPTEIVESFNLLSGYFPLIKNLIVDRKKAVPFTASQSYRYKLA--LEEI-----------RDSL-YLDGKPHSLRQKHLRNLQIVDLLVELVLLPFHSKIDA-------------AFTEKIYRASFEILHNYMKGSSIKNSLYFAKYINLFEPKMLENNDLGHKII--EMIAELLRNNQKVLE-CISFQEIFPFIDNLRINQNFRYLEYLETFCVCNGE--PMTQNQIKIAVKWLSEDQRGVFLTDR-------GQNLNLESNVIYIKTKLDSNWMKLHEFLDITAQIDQENNPLYHQDNKD----------YFLKQMDLLLALCYGRNQYCTNLIINKLNYISWEQCFAAINSPMIPPYMKTKYFEIIQTMFIDIGRNYAVIESP-KFNFIFNQIQGDSSVAVECMFPTPSESVTIK-IFKDLSEWIYNFLEST--PRMISSNKDFNYLIRIVFITINKLIQYGYYDSPSLDRICKSLLKLLN 2746
            M+ +L  GD   LY E  TNGFI++         L +   +    PE   D+       ++ +F++   NRY   K++ K  K   N + +  L  +   A      E+  N  ENR+ LG  + YG+VIQL H+ + KY+ VN    +  ++N+M + L     + + F I P YK++  G+ V   D V    + A     HAS    +DN       ++    S    L    SD     +D+ L+GGD +++ H E + ++  +  +   KK  ++LR   +   Q+ T++   +S+   W+VE+ +        G W+S FRF+H     YL+ +                   +D S S  +NA               + +++F L P  +     ++P   Y R+ H+ T TW+H+    +          D  E+    LK  T+ L+E          +AF +  V    V   +  +    ++ ++    +K    T +Q+ R  +   LE++           +D L  +  KP+  RQK +R   I+  + +L+  PF    D              A    I R  + +L +  +    KN  Y AK     + +      +G+ ++  + I  LL NN+K+LE  I+  EI  F+  +R N+  R+L+YL   CV   +  P+TQ  I  AV  L+     + +  +        + ++   N +      +  W+    + D   +I  ++     QD K+          Y+  Q++L   +C  R     N I  +L+     +C +  N   +P  ++  +  ++  M +D  R+     +P K+  ++++I   S +A++    + +    IK  F    E++  +L      R   S+K+ N L   V      LI +G+Y+   L R+ K LL +L+
Sbjct:    5 MSSFLHIGDICSLYAEGSTNGFIST---------LGLVDDRCVVQPE-AGDLNNPPKKFRDCLFKLCPMNRYSAQKQFWKAAKPGANSTTDAVLLNKLHHAADL---EKKQNETENRKLLGTVIQYGNVIQLLHLKSNKYLTVNKRLPALLEKNAMRVTLDEAGNEGSWFYIQPFYKLRSIGDSVVIGDKVVLNPVNA-GQPLHASSHQLVDNPGCNEVNSVNCNTSWKIVLFMKWSDN----KDDILKGGDVVRLFHAEQEKFLTCDEHR---KKQHVFLR---TTGRQSATSA---TSSKALWEVEVVQHDPCRGGAGYWNSLFRFKHLATGHYLAAEVDPDFEEECLEFQPSVDPDQDASRSRLRNAQEKMVYSLVSVPEGNDISSIFELDPTTLRGGDSLVPRNSYVRLRHLCTNTWVHSTNIPI----------DKEEEKPVMLKIGTSPLKE--------DKEAFAIVPVSPAEVRDLDFANDASKVLGSIAGKLEKG---TITQNERRSVTKLLEDLVYFVTGGTNSGQDVLEVVFSKPNRERQKLMREQNILKQIFKLLQAPFTDCGDGPMLRLEELGDQRHAPFRHICRLCYRVLRHSQQDYR-KNQEYIAKQFGFMQKQ------IGYDVLAEDTITALLHNNRKLLEKHITAAEIDTFVSLVRKNREPRFLDYLSDLCVSMNKSIPVTQELICKAV--LNPTNADILIETKLVLSRFEFEGVSTGENALEAGEDEEEVWLF---WRDSNKEIRSKSVRELAQDAKEGQKEDRDILSYYRYQLNLFARMCLDRQYLAINEISGQLDVDLILRCMSDEN---LPYDLRASFCRLMLHMHVD--RDPQEQVTPVKYARLWSEIP--SEIAIDDYDSSGTSKDEIKERFAQTMEFVEEYLRDVVCQRFPFSDKEKNKLTFEVVNLARNLIYFGFYNFSDLLRLTKILLAILD 896          

HSP 2 Score: 82.8037 bits (203), Expect = 5.966e-14
Identity = 48/147 (32.65%), Postives = 75/147 (51.02%), Query Frame = 3
Query: 7584 VDTFSELRDLKYKTEKDMKETCFICSRAGHDFDQSSSSFEHHVVYEHNMWAYLFYFLHLKEIKINDYFHLDLYVANMLKRENYDFFPINCALSLT-----AEQEKYSRIDEISRNVKIIVSN----------RQNEEREKLRRTNLF 7979
            +DTF++LR  K K E+ +K TCFIC      FD  + +FE H+  EHNMW YL + + +K     +Y   + YVA M++  N D+FP   A+SL       EQ +   + E   +   +V+N          +  E+R++ +R  L 
Sbjct: 2589 IDTFADLRSEKQKKEEILKTTCFICGLERDKFDNKTVTFEEHIKEEHNMWHYLCFIVLVKVKDSTEYTGPESYVAEMIRERNLDWFPRMRAMSLVSSDSEGEQNELRNLQEKLESTMKLVTNLSGQLSELKDQMTEQRKQKQRIGLL 2735          
BLAST of Inositol 1,4,5-trisphosphate receptor type 3 vs. UniProt/SwissProt
Match: sp|Q8WN96|ITPR2_BOVIN (Inositol 1,4,5-trisphosphate receptor type 2 OS=Bos taurus OX=9913 GN=ITPR2 PE=2 SV=1)

HSP 1 Score: 120.939 bits (302), Expect = 1.463e-25
Identity = 173/710 (24.37%), Postives = 294/710 (41.41%), Query Frame = 2
Query:  164 MNDYLSYGDRICLYCEET-NGFINSNNSSSHYNELRIFSKQDKFNPENVSDI-------QEIIFEVVIQNRXXXXXXX-XXXXXDINNKSENLELKIQAEQAKATVISEENDNALENRRNLGKTVHYGDVIQLRHVYTRKYIHVNIAKTSSKDQNSMILNLQSHNLKSAQFKIVPRYKVKYEGEPVQFMDLVTFESLKAPSHYFHASDLYQIDNFFHGA----ALNLATEQSGFTLIKSASDTHIMEEDNFLRGGDYIQIIHKEIDGYIESEGIQGGMKKADIYLRIRKSDKFQTLTNSRLS-SSANTFWQVEI---EKVRLSTEIGQWSSNFRFRHATNRLYLSVK-----------------KDLSVSMTKNATNPNTVFRL--YPQNID---------------KLIIPYGRYFRMEHVLTGTWIHANKEQVYVKPNQSKYDDAAEKCLGNLKYETNELRELFCVHQRLYDDAFVVFKVPTEIVESFNLLSGYFPLIKNLIVDRKKAVPFTASQSYRYKLALEEIRDSLY---------------LDGKPHSLRQKHLRNLQIVDLLVELVLLPFHSKIDAAFTEKI----------YRASFEILHNYMKGSS---IKNSLYFAKYINLFEPKMLENNDLGHKII--EMIAELLRNNQKVLE-CISFQEIFPFIDNLRINQNFRYLEYLETFCVCNGE--PMTQNQI 2041
            M+ +L  GD + LY E + NGFIN+         L +   +   +PE   D+       ++ +F+V   NRY   K+Y         N +E   LK     A+     E+  N  EN++ LG+ V Y +VIQL H+ + KY+ VN    +  ++N+M ++L +   + + F I P +K++ EG+ +     V    + A     HAS++  +DN   G     A+N  T       +K +S       ++ L+GGD +++ H E + ++  +  +   KK  I+LR        TL  S  S +S+   W++E+   +  R     GQW+S FRF+H     YL+ +                  DL  S  K       ++ L   P   D                 ++P   Y R+ H+ T TW+ +    +          D  E+    LK  T + +E          +AF +  VP   V   +  +    ++   +   KK    T +Q+ R +   + + D ++               L  KP+  RQK +R   I+  +  ++  PF  K       ++          Y+    + +  +  S     KN  Y AK   + + +      +G+ I+  + I  LL NN+K+LE  I+ +EI  F+  LR N+  R+L+YL   CV N    P+TQ  I
Sbjct:    5 MSSFLYIGDIVSLYAEGSVNGFINT---------LGLVDDRCVVHPE-AGDLANPPKKFRDCLFKVCPMNRYSAQKQYWKAKQAKQGNHTEAALLKKLQHAAEL----EQKQNESENKKLLGEIVKYSNVIQLLHIKSNKYLTVNKRLPALLEKNAMRVSLDAAGNEGSWFYIHPFWKLRSEGDNIVVGGKVVLMPVNA-GQPLHASNIELLDN--PGCKEVNAVNCNTSWKITLFMKYSS-----YREDVLKGGDVVRLFHAEQEKFLTCDEYE---KKQHIFLRT-------TLRQSATSATSSKALWEIEVVHHDPCRGGA--GQWNSLFRFKHLATGNYLAAELNPDYRDAQNEGKNVRDGDLPASKKKRQAGEKIMYTLVSVPHGNDIASLFELDATTLQRADCLVPRNSYVRLRHLCTNTWVTSTSIPI----------DTDEERPVMLKIGTCQTKE--------DKEAFAIVSVPPSEVRDLDFANDANKVLATTV---KKLENGTITQNER-RFVTKLLEDLIFFVADVPNNGQDVLDVLITKPNRERQKLMREQNILAQVFGILKAPFKEKAGEGSMLRLEDLGDQRYAPYKYMLRLCYRVLGHSQQDYRKNQEYIAKNFCVMQSQ------IGYDILAEDTITALLHNNRKLLEKHITAKEIETFVSLLRRNREPRFLDYLSDLCVSNTTAIPVTQELI 652          

HSP 2 Score: 83.9593 bits (206), Expect = 2.703e-14
Identity = 40/98 (40.82%), Postives = 59/98 (60.20%), Query Frame = 3
Query: 7584 VDTFSELRDLKYKTEKDMKETCFICSRAGHDFDQSSSSFEHHVVYEHNMWAYLFYFLHLKEIKINDYFHLDLYVANMLKRENYDFFPINCALSLTAEQ 7877
            +DTF++LR  K K E+ +K TCFIC      FD  + SFE H+  EHNMW YL++ + +K     +Y   + YVA M+  +N D+FP   A+SL + +
Sbjct: 2541 IDTFADLRSEKQKKEEILKTTCFICGLERDKFDNKTVSFEEHIKSEHNMWHYLYFLVLVKVKDPTEYTGPESYVAQMIVEKNLDWFPRMRAMSLVSSE 2638          
BLAST of Inositol 1,4,5-trisphosphate receptor type 3 vs. UniProt/SwissProt
Match: sp|Q14571|ITPR2_HUMAN (Inositol 1,4,5-trisphosphate receptor type 2 OS=Homo sapiens OX=9606 GN=ITPR2 PE=1 SV=2)

HSP 1 Score: 117.087 bits (292), Expect = 2.338e-24
Identity = 171/708 (24.15%), Postives = 298/708 (42.09%), Query Frame = 2
Query:  164 MNDYLSYGDRICLYCEET-NGFINS-----NNSSSHYNELRIFSKQDKFNPENVSDIQEIIFEVVIQNRXXXXXXX-XXXXXDINNKSENLELKIQAEQAKATVISEENDNALENRRNLGKTVHYGDVIQLRHVYTRKYIHVNIAKTSSKDQNSMILNLQSHNLKSAQFKIVPRYKVKYEGEPVQFMDLVTFESLKAPSHYFHASDLYQIDNFFHGA----ALNLATEQSGFTLIKSASDTHIMEEDNFLRGGDYIQIIHKEIDGYIESEGIQGGMKKADIYLRIRKSDKFQTLTNSRLSS-SANTFWQVEI---EKVRLSTEIGQWSSNFRFRHATNRLYLSVK---------------KDLSVSMTK--------------NATNPNTVFRLYPQNIDKL-----IIPYGRYFRMEHVLTGTWIHANKEQVYVKPNQSKYDDAAEKCLGNLKYETNELRELFCVHQRLYDDAFVVFKVPTEIVESFNLLSGYFPLIKNLIVDRKKAVPFTASQSYRYKLALEEIRDSLY------------LD---GKPHSLRQKHLRNLQIVDLLVELVLLPFHSKIDAAFTEKI----------YRASFEILHNYMKGSS---IKNSLYFAKYINLFEPKMLENNDLGHKII--EMIAELLRNNQKVLE-CISFQEIFPFIDNLRINQNFRYLEYLETFCVCNGE--PMTQNQI 2041
            M+ +L  GD + LY E + NGFI++     +    H     + +   KF        ++ +F+V   NRY   K+Y         N +E   LK     A+     E+  N  EN++ LG+ V Y +VIQL H+ + KY+ VN    +  ++N+M ++L +   + + F I P +K++ EG+ +   D V    + A     HAS++  +DN   G     A+N  T       +K +S       ++ L+GGD +++ H E + ++  +  +   KK  I+LR        TL  S  S+ S+   W++E+   +  R     GQW+S FRF+H     YL+ +               +D     +K              +  + N +  L+  +   L     ++P   Y R+ H+ T TW+ +    +          D  E+    LK  T + +E          +AF +  VP   V   +  +    ++   +   KK    T +Q+ R +   + + D ++            LD    KP+  RQK +R   I+  +  ++  PF  K       ++          Y+    + +  ++ S     KN  Y AK   + + +      +G+ I+  + I  LL NN+K+LE  I+ +EI  F+  LR N+  R+L+YL   CV N    P+TQ  I
Sbjct:    5 MSSFLYIGDIVSLYAEGSVNGFISTLGLVDDRCVVHPEAGDLANPPKKF--------RDCLFKVCPMNRYSAQKQYWKAKQAKQGNHTEAALLKKLQHAAEL----EQKQNESENKKLLGEIVKYSNVIQLLHIKSNKYLTVNKRLPALLEKNAMRVSLDAAGNEGSWFYIHPFWKLRSEGDNIVVGDKVVLMPVNA-GQPLHASNIELLDN--PGCKEVNAVNCNTSWKITLFMKYSS-----YREDVLKGGDVVRLFHAEQEKFLTCDEYE---KKQHIFLRT-------TLRQSATSATSSKALWEIEVVHHDPCRGGA--GQWNSLFRFKHLATGNYLAAELNPDYRDAQNEGKNVRDGVPPTSKKKRQAGEKIMYTLVSVPHGNDIASLFELDATTLQRADCLVPRNSYVRLRHLCTNTWVTSTSIPI----------DTDEERPVMLKIGTCQTKE--------DKEAFAIVSVPLSEVRDLDFANDANKVLATTV---KKLENGTITQNER-RFVTKLLEDLIFFVADVPNNGQEVLDVVITKPNRERQKLMREQNILAQVFGILKAPFKEKAGEGSMLRLEDLGDQRYAPYKYMLRLCYRVLRHSQQDYRKNQEYIAKNFCVMQSQ------IGYDILAEDTITALLHNNRKLLEKHITAKEIETFVSLLRRNREPRFLDYLSDLCVSNTTAIPVTQELI 652          

HSP 2 Score: 83.5741 bits (205), Expect = 3.334e-14
Identity = 40/98 (40.82%), Postives = 59/98 (60.20%), Query Frame = 3
Query: 7584 VDTFSELRDLKYKTEKDMKETCFICSRAGHDFDQSSSSFEHHVVYEHNMWAYLFYFLHLKEIKINDYFHLDLYVANMLKRENYDFFPINCALSLTAEQ 7877
            +DTF++LR  K K E+ +K TCFIC      FD  + SFE H+  EHNMW YL++ + +K     +Y   + YVA M+  +N D+FP   A+SL + +
Sbjct: 2541 IDTFADLRSEKQKKEEILKTTCFICGLERDKFDNKTVSFEEHIKSEHNMWHYLYFIVLVKVKDPTEYTGPESYVAQMIVEKNLDWFPRMRAMSLVSNE 2638          
BLAST of Inositol 1,4,5-trisphosphate receptor type 3 vs. UniProt/SwissProt
Match: sp|Q63269|ITPR3_RAT (Inositol 1,4,5-trisphosphate receptor type 3 OS=Rattus norvegicus OX=10116 GN=Itpr3 PE=1 SV=1)

HSP 1 Score: 112.464 bits (280), Expect = 5.960e-23
Identity = 167/699 (23.89%), Postives = 295/699 (42.20%), Query Frame = 2
Query:  164 MNDYLSYGDRICLYCEET-NGFINSNNSSSHYNELRIFSKQDKFNPENVSDIQEIIFEVVIQNRXXXXXXXXXXXXDINNKSENLELKI-QAEQAKATVISEENDNALENRRNLGKTVHYGDVIQLRHVYTRKYIHVNIAKTSSKDQNSMILNLQSHNLKSAQFKIVPRYKVKYEGEPVQFMDLVTFESLKAPSHYFHASDLYQIDNFFHGAALNLATEQSGFTLIKSASDTHIMEEDNFLRGGDYIQIIHKEIDGYIESEGIQGGMKKADIYLRIRKSDKFQTLTNSRLSS-SANTFWQVEI---EKVRLSTEIGQWSSNFRFRHATNRLYLSVKKDLS----VSMTKNATNPN----------------------------TVFRLYPQNIDKL--IIPYGRYFRMEHVLTGTWIHANKEQVYVKPNQSKYDDAAEKCLGNLKYETNELRELFCVHQRLYDDAFVVFKVPTEIVESFNLLSGYFPLIKNLIVDRKKAVPFTASQSYRYKLALEEIRDSLY------------LD---GKPHSLRQKHLRNLQIVDLLVELVLLPFHSKIDAAFTEKI----------YRASFEILHNYMKGSS---IKNSLYFAKYINLFEPKMLENNDLGHKII--EMIAELLRNNQKVLE-CISFQEIFPFIDNLRINQNFRYLEYLETFCVCN--GEPMTQNQI 2041
            M+ +L  GD + LY E + NGFI++         +   +  D  NP      ++ +F+V   NRY   K+Y K  +   +K +  ++ + Q  Q  A +  ++ND   EN++  G  V YG VIQL H+ + KY+ VN    +  ++N+M + L +   + +   I P +K++  G+ V   D V    + A     HAS+ Y++ +      +N     + + +         +EE   L+GGD +++ H E + ++  +  +G   K  ++LR        TL  S  S+ S+N  W+VE+   +  R     G W+  +RF+H     YL+ +++ S    VS  K A  P                             ++F L P  + K    +P   Y R+ H+ T TWI +    + V+  +          LG     T E +E           AF +  VP   +   +  +    ++ + +   K    F +    R+ + L E  D ++            LD    KP+  RQK +R+  I+  +  ++  PF  K       ++          Y+  F + +  ++ S     KN  + AK   + + +      +G+ I+  + I  LL NN+K+LE  I+  E+  F+  +R N+  R+L+YL   CV N    P+TQ  I
Sbjct:    4 MSSFLHIGDIVSLYAEGSVNGFISTLGLVDDRCVVEP-AAGDLDNPPK--KFRDCLFKVCPMNRYSAQKQYWKAKQTKQDKEKIADVVLLQKLQHAAQMEQKQNDT--ENKKVHGDVVKYGSVIQLLHMKSNKYLTVNKRLPALLEKNAMRVTLDATGNEGSWLFIQPFWKLRSNGDNVVVGDKVILNPVNA-GQPLHASN-YELSDNVGCKEVNSVNCNTSWKINLFMQFRDHLEE--VLKGGDVVRLFHAEQEKFLTCDEYRG---KLQVFLRT-------TLRQSATSATSSNALWEVEVVHHDPCRGGA--GHWNGLYRFKHLATGNYLAAEENPSYKGDVSDPK-AAGPGAQSRTGRRNAGEKIKYRLVAVPHGNDIASLFELDPTTLQKTDSFVPRNSYVRLRHLCTNTWIQSTNAPIDVEEER-----PIRLMLGTCP--TKEDKE-----------AFAIVSVPVSEIRDLDFANDASSMLASAV--EKLNEGFISQNDRRFVIQLLE--DLVFFVSDVPNNGQNVLDIMVTKPNRERQKLMRDENILKQIFGILKAPFRDKGGEGPLVRLEELSDQKNAPYQYMFRLCYRVLRHSQEDYRKNQEHIAKQFGMMQSQ------IGYDILAEDTITALLHNNRKLLEKHITKTEVETFVSLVRKNREPRFLDYLSDLCVSNRIAIPVTQELI 652          

HSP 2 Score: 87.4261 bits (215), Expect = 2.365e-15
Identity = 41/96 (42.71%), Postives = 59/96 (61.46%), Query Frame = 3
Query: 7584 VDTFSELRDLKYKTEKDMKETCFICSRAGHDFDQSSSSFEHHVVYEHNMWAYLFYFLHLKEIKINDYFHLDLYVANMLKRENYDFFPINCALSLTA 7871
            +DTF++LR  K K E+ +K TCFIC      FD  + SFE H+  EHNMW YL++ + ++     DY   + YVA M+K +N D+FP   A+SL +
Sbjct: 2516 IDTFADLRSEKQKKEEILKTTCFICGLERDKFDNKTVSFEEHIKLEHNMWNYLYFIVLVRVKNKTDYTGPESYVAQMIKNKNLDWFPRMRAMSLVS 2611          
BLAST of Inositol 1,4,5-trisphosphate receptor type 3 vs. UniProt/SwissProt
Match: sp|P70227|ITPR3_MOUSE (Inositol 1,4,5-trisphosphate receptor type 3 OS=Mus musculus OX=10090 GN=Itpr3 PE=1 SV=3)

HSP 1 Score: 111.309 bits (277), Expect = 1.227e-22
Identity = 165/698 (23.64%), Postives = 294/698 (42.12%), Query Frame = 2
Query:  164 MNDYLSYGDRICLYCEET-NGFINSNNSSSHYNELRIFSKQDKFNPENVSDIQEIIFEVVIQNRXXXXXXXXXXXXDINNKSENLELKI-QAEQAKATVISEENDNALENRRNLGKTVHYGDVIQLRHVYTRKYIHVNIAKTSSKDQNSMILNLQSHNLKSAQFKIVPRYKVKYEGEPVQFMDLVTFESLKAPSHYFHASDLYQIDNFFHGAALNLATEQSGFTLIKSASDTHIMEEDNFLRGGDYIQIIHKEIDGYIESEGIQGGMKKADIYLRIRKSDKFQTLTNSRLSS-SANTFWQVEI---EKVRLSTEIGQWSSNFRFRHATNRLYLSVKKDLS----VSMTKNA---------------------------TNPNTVFRLYPQNIDKL--IIPYGRYFRMEHVLTGTWIHANKEQVYVKPNQSKYDDAAEKCLGNLKYETNELRELFCVHQRLYDDAFVVFKVPTEIVESFNLLSGYFPLIKNLIVDRKKAVPFTASQSYRYKLALEEIRDSLY------------LD---GKPHSLRQKHLRNLQIVDLLVELVLLPFHSKIDAAFTEKI----------YRASFEILHNYMKGSS---IKNSLYFAKYINLFEPKMLENNDLGHKII--EMIAELLRNNQKVLE-CISFQEIFPFIDNLRINQNFRYLEYLETFCVCN--GEPMTQNQI 2041
            M+ +L  GD + LY E + NGFI++         +   +  D  NP      ++ +F+V   NRY   K+Y K  +   +K +  ++ + Q  Q  A +  ++ND   EN++  G  V YG VIQL H+ + KY+ VN    +  ++N+M + L +   + +   I P +K++  G+ V   D V    + A     HAS+ Y++ +      +N     + + +         +EE   L+GGD +++ H E + ++  +  +G   K  ++LR        TL  S  S+ S+N  W+VE+   +  R     G W+  +RF+H     YL+ +++ S    VS  K A                            +  ++F L P  + K    +P   Y R+ H+ T TWI +    + V+  +          LG     T E +E           AF +  VP   +   +  +    ++ + +   K    F +    R+ + L  + D ++            LD    KP+  RQK +R   I+  +  ++  PF  K       ++          Y+  F + +  ++ S     KN  + AK   + + +      +G+ I+  + I  LL NN+K+LE  I+  E+  F+  +R N+  R+L+YL   CV N    P+TQ  I
Sbjct:    4 MSSFLHIGDIVSLYAEGSVNGFISTLGLVDDRCVVEP-AAGDLDNPPK--KFRDCLFKVCPMNRYSAQKQYWKAKQTKQDKEKIADVVLLQKLQHAAQMEQKQNDT--ENKKVHGDVVKYGSVIQLLHMKSNKYLTVNKRLPALLEKNAMRVTLDATGNEGSWLFIQPFWKLRSNGDNVVVGDKVILNPVNA-GQPLHASN-YELSDNAGCKEVNSVNCNTSWKINLFMQFRDHLEE--VLKGGDVVRLFHAEQEKFLTCDEYRG---KLQVFLRT-------TLRQSATSATSSNALWEVEVVHHDPCRGGA--GHWNGLYRFKHLATGNYLAAEENPSYKGDVSDPKAAGLGAQGRTGRRNAGEKIKYRLVAVPHGNDIASLFELDPTTLQKTDSFVPRNSYVRLRHLCTNTWIQSTNAPIDVEEER-----PIRLMLGTCP--TKEDKE-----------AFAIVSVPVSEIRDLDFANDASSMLASAV--EKLNEGFISQNDRRFVIQL--LEDLVFFVSDVPNNGQNVLDIMVTKPNRERQKLMREQNILKQIFGILKAPFRDKGGEGPLVRLEELSDQKNAPYQYMFRLCYRVLRHSQEDYRKNQEHIAKQFGMMQSQ------IGYDILAEDTITALLHNNRKLLEKHITKTEVETFVSLVRKNREPRFLDYLSDLCVSNRIAIPVTQELI 652          

HSP 2 Score: 87.4261 bits (215), Expect = 2.086e-15
Identity = 48/134 (35.82%), Postives = 78/134 (58.21%), Query Frame = 3
Query: 7584 VDTFSELRDLKYKTEKDMKETCFICSRAGHDFDQSSSSFEHHVVYEHNMWAYLFYFLHLKEIKINDYFHLDLYVANMLKRENYDFFPINCALSLT-----AEQEKYSRIDE-ISRNVKII--VSNRQNEEREKL 7961
            +DTF++LR  K K E+ +K TCFIC      FD  + SFE H+  EHNMW YL++ + ++     DY   + YVA M+K +N D+FP   A+SL       EQ +   + E +   +K++  ++++ NE +E++
Sbjct: 2516 IDTFADLRSEKQKKEEILKTTCFICGLERDKFDNKTVSFEEHIKLEHNMWNYLYFIVLVRVKNKTDYTGPESYVAQMIKNKNLDWFPRMRAMSLVSGEGEGEQNEIRILQEKLGSTMKLVSHLTSQLNELKEQM 2649          
BLAST of Inositol 1,4,5-trisphosphate receptor type 3 vs. TrEMBL
Match: A0A267E835 (Uncharacterized protein (Fragment) OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig032795g1 PE=4 SV=1)

HSP 1 Score: 1207.59 bits (3123), Expect = 0.000e+0
Identity = 771/2236 (34.48%), Postives = 1251/2236 (55.95%), Query Frame = 2
Query:  407 ENLELKIQAEQAKATVISEENDNALENRRNLGKTVHYGDVIQLRHVYTRKYIHVNIAKTSSKDQNSMILNLQSHNLKSAQFKIVPRYKVKYEGEPVQFMDLVTFESLKAPSHYFHASDLYQIDNFFHGAALNLATEQSGFTLIKSASDTHIMEEDNFLRGGDYIQIIHKEIDGYIESEGIQGGMKKADIYLRIRKSDKFQTLTNSRLSSSANTFWQVEIEKVRLSTEIGQWSSNFRFRHATNRLYLSVKKDLS---VSMTKNATNPNTVFRLYPQNIDKLIIPYGRYFRMEHVLTGTWIHANKEQVYVKPNQSKYDDAAEKCLGNLKYETNELRELFCVHQRLYDDAFVVFKVPTEIVESFNLLSGYFPLIKNLIVDRKKAVPFTASQSYRYKLALEEIRDSLYLDGKPHSLRQKHLRNLQIVDLLVELVLLPFHSKIDAAFTEKIYRASFEILHNYMKGSSIKNSLYFAKYINLFEPKMLENNDLGHKIIEMIAELLRNNQKVLECISFQEIFPFIDNLRINQNFRYLEYLETFCVCNGEPMTQNQIKIAVKWLSEDQRGVFLTDRGQNLNLESNVIYIKTKLDSNWMKLHEFLDITAQIDQENNPLYHQDNKDYFLK-QMDLLLALCYGRNQYCTNLIINKLNYISWEQCFAAINSPMIPPYMKTKYFEIIQTMFIDIGRNYAVIESPKFNFIFNQIQGDSSVAVECMFPTPSESVTIKIFKDLSEWIYNFLESTPRMISSNKDFNYLIRIVFITINKLIQYGYY-DSPSLDRICKSLLKLLNGRNDLPFEYD----SKKESLKIRKKLVTKYKNISRYEDSEETRAIVAAKLSGLEILDSILIYERVSVVAKLISRFKKCVQPDLKVQKKRLTGHTHLEACLS--NGFDVAQQYKQSNRATKKMVSEIDNLF-TTARFLDSEPWTNILIDLAHYQNEMMTQKSLLILHKLYSIKESSFQDTYATFISKTKQSQDLQELMCEYIPALRLHTKSLIGPPDLEKIAAMITEMINVCKIPKS-DSFNPISQRIIVGYGILDI-----AMETIAQIYRSFDRSKMMYGASEVISLITNLLRHLAISNPSFQEXXXXXXXXXXXXYEHSPPAELADLLRCGL------------FHNNRTFCGTLKSFQINKIVLMVADTARKNPLVGAAFIHLLESIVAVNNGEVPLKRNQLMVMKFVMKSFNQLVYILDSKSM-SRVDLLTIHSASNDAFYFTKVIDLFIACCQGENQYVQSLCQTIMPLDELFDLLTHNDISIIYKRGLLKYFSKVYLSRTNISNQEGIIKNFIESKYCGEI---LDSIERTTL-LTQIILDKTEHFNLLPILKKEF--ILK-----PPTEFQVSEN-------------IQMH---------LHYIIFGSSIFMASLCSAFSIM-EISPAPELMKVIKSINHITMDIFSQMWKFQLHPSVFSVITESVLQII--SYTDTSDLE------AKTMALQHCKPQIMDFDPRKEIDNLYTEEIELNLKLQTFIFNCSQLIAGQNTVKAQIKANLRKQYVNLLDQNALPLNLEYQNHLKCFINNSYQKGEIRRYKLVDILIRQLEISGSVERNGKRHTKLDRNSFSKTIKRLDQDALDLRSLQILRGLIYNEECLLPDNWELKIFNSSVQDILKCIKNVQNCLNKLNLSSRTQIHMVNSCDLVKREAITLQSAMLMNANKNVQESLLRYFKGAQEEVFFSAIKYQLQNAFTDLKDQKLMLSQKKSFGDIEKYTCHESDLRID-NLAHILYQQLAEY--EIRYEDQNRSLAINRYAYTTTKESFTTRHMRQIYTPAKMKSEINSSSPLICCPRNSSKSNYDMRSTDKSDSLFKNNLQDEYE---LKSVVTKESNSSTDKTIENSA---WIKGETLDLMRNDPHQNVKLILQLLSRMCVGQYQGLQNYLRIQPDNRSSVDVISLIVQFLGNIYANVRQSTIDLSIQAFDTIKETIMGNQENRSVVYRAKVVDYANFILRNDEISETCDPNNVLQMFLVIGRVIMALIEENGREETELAKEIQITLDIKAVFKIMTRCLDMMEDTKR--------------KLIKNKIYDVGFTYFLILARLEDL--CNGK-----LLKHFQISDQQMKAXXXXXXGSASVEILKGDQLQRIHFRLKHKEVLRESVKEKVKWEVDRTTPSNKIRSFISWSKLILPDMNFQRKIIQNPLLLFVTKQWNAMNYFLTLLSLVINIL 6805
            E LE K   EQA+    +E  DN  E +RN GK V YG++IQL+HV+T K++HVN  +TS  D+N+M+L+L   N K+AQF+I+PRYKVK EGE VQ +D  +FES+K+P H+FHAS  + I+     + LNL  +Q+GFT++KS   TH  E + F RGG ++Q+ HKE++ Y+ +EG+        ++LRIR+ D+    T  R S+SA T+WQVE EK  L+ +I  W   FRFRHAT R YL ++++ S   VS+  +AT+P+TVF+L+P   +   + +  Y R+EHV+TG+W+HA K++ Y +      +D  EK +  L+++  ELRE+ C   R YDDA+ + KV    V++FN ++G  P ++NLI  R+        +++    AL+E+RD + ++G+P   +QK LRNL+++DLLV L+  P     D     +++  +++ILH YM G+S KN+LYFAKYI  F+ +M++ +DL  K+ +M+ EL+++N+K+++ IS ++I  F+D LR N+++ YLE L+  CVCNG  +T NQ  IA KWL ED RG++L++RGQN++ + N  Y+ T     W  L +F+    + DQE+        +  FL+ Q+DL +ALC+GRN+ C  LI   L+Y++WE+ +  ++S  +P   + KY EI+  +F+++G NY+V+ESP+ +FI+  +    SV         +    I +F  + +WI  FL+    M+++    N LI  V   ++ L+++GYY D   L  +   L  LLNG ND+PF  D     + +  K  KK+V ++K   RY+ S +T AIV AK + L +LD ++ ++  + +A  IS+FK C   ++K ++ R   H  + A  S  + FD  +  ++   A +K   E+  +F  ++R+LD++  T ILIDLA+Y+ + M + SL +L+KLYS K S FQ    + +  T  S  +   + + +P LR+  +S        K+  ++ E+  +C +PK+ +  +P++QR+++ + IL +     A ET AQ+  ++  +      + V+     LL+ L +  P  QE +F               A L DLLR  L            F NN+  C  +   QI +IV +VA+   + P     F+ LL +IV V    + LKRNQ +VMK++M++++++ YIL+  S+  R+D+L  +  ++   Y    IDL   C +GEN+Y++SLCQTI+ + E+  +L   D+    K+  L+Y    Y+ +T  +  E    + I      +I   LD + R  L L   I D  +   +  +  K F  I++     P     VSE+             ++M          LHY+      F+ +    F ++ E        ++   +    ++   Q+    + P V + +   +  I+  S    S +E       K   LQ    Q+   +  KE    Y +EI LN KL++   N S L  G NTVKAQ+K N  ++Y  +    ALPL+ E+Q+H++C I    +K E +RYKL  +L+  L I  +   +G  H      + ++T  R +Q+ L +R LQILR  ++NEE  LP +WE++     V+  L+ I ++Q  LN   L      H+ ++  LV +E ++L   ML NAN+ VQES+L YF   +EEVFF A++ +LQ +  ++K+++L++SQ+K+     K      +LR    L     QQ+ +Y  E++ E  N  L        T + S T    + + T  K + E  S +P       S+ S      +      F N L+ E +    +S++ + ++S +   +EN A     + ET+  M++D +  + L+L++L+ +C GQ+ GLQNYLR QPDN  S ++++ + QF+   Y+N+   TIDL IQ F T+ E   GNQENR+ VY  K++DY NFILR+ +  E+C+P  V+Q+   I  ++++LIEEN  E   +A+E++ TLD  A+++ M+ C +  + T +              + +K  +Y+VGFT+++ILARL D+    GK       +  QISD Q KAFKFFKK + ++EILK D LQ++HFR+++K VLRE +KEK+KW VDR++PS KIR F+ W+K IL D+++Q+K++ NP  + +T+ W   N+  TL +++IN++
Sbjct:  171 ETLEAKQHFEQARCAANAENVDNMAEQKRNQGKRVRYGEIIQLKHVFTGKFVHVNTNQTSQYDKNNMLLSLHEFNSKNAQFRILPRYKVKSEGEYVQLLDQTSFESIKSPGHFFHASHGFPIEAGRIVSELNLGVDQTGFTILKS--HTHYGEFEAFARGGQFVQLFHKELEAYVVAEGLFDDEVTEGVHLRIREVDQLNART-LRQSTSAITYWQVESEKTMLNGDILTWDQQFRFRHATTRKYLCLQQEGSGYVVSLLDDATDPHTVFKLHPVLQETAELKFESYARIEHVITGSWLHAIKDKAYERREFLNMED--EKSMKALRWDGGELREVTCCSDRRYDDAYTIKKVEQLQVQNFNFVAGMVPFLQNLIAMRQSGKQLVGKETFGICHALKELRDFMVVNGEPCKEKQKLLRNLRVIDLLVTLLKFPLKGTSDEHNLSRVFYYAYDILHTYMLGNSRKNALYFAKYIEFFQTQMIDKSDLALKVTKMLVELMKDNRKIVDRISKEQIDDFVDLLRKNEHYSYLELLKVLCVCNGVAITDNQSYIAQKWLLEDTRGIYLSERGQNIDRKPNETYVSTDQMKTWTPLVDFVQ-PDESDQESV------ERCLFLRTQLDLFIALCHGRNEECIRLITKDLSYLTWEEAYLGLSSDSLPQAFRAKYCEIVIGLFVNVGNNYSVVESPQLSFIYEYVGTKDSVGSATAPDQYAAKDLITVFPVIRDWITQFLDQNRFMVAAQIPNNMLIEQVLRLLHYLVKFGYYGDVHDLAMLLPPLKNLLNGENDVPFLPDKSSQGRADYTKDNKKIVQRFKQHDRYKKSPQTLAIVNAKHAALRVLDLVMTFQENARLASFISKFKDCEMSEVKKKQAR---HPMVPALYSSFDSFDTKKSARKKQNAIRK---ELRIMFDESSRYLDTDNLTAILIDLANYEYDPMVELSLQLLNKLYSSKSSMFQRAINSLVLTTPDSCRVHREVSKQVPLLRMTARSKWTAEQARKMQTILGELYELCHLPKAEEEPHPMNQRLMISHNILPVIFDILATETDAQLSENYVET------AGVLRKAVRLLKALTLRYPDVQEQVF---------------AHLDDLLRVRLVESDLALALKEVFANNQELCLRVLPKQILRIVYLVAEHQERAP----EFLELLSAIVKVEGTGLALKRNQTLVMKYIMQNYSRVAYILEQCSVKDRMDVLNGNRGADHCQYLVSFIDLLATCAEGENRYIESLCQTILSVQEILGILNDPDVENHLKKPFLRYMFFAYM-KTTAAAGENRSLDIIHDSVTWQIWDYLDHLGRELLGLAYWIRDDADRDTVYFMTAKPFPKIMRLHDTCPLCSSLVSEDESKPLKLNLENAVVKMREDDYRGHSSLHYVFDAVFPFLQAFAQKFYVVDEDKDFQNEREIFDRMTTGAVEFCCQLASIVVEPKVLTQMVSCLSCIVKRSSHPPSIMEPVVENIGKGTKLQDTVSQMKSGN--KE---YYEQEIILNTKLKSLAVNLSLLWGGHNTVKAQLKVNSNREYTTIGGDEALPLDEEFQSHVRCLIGMGSRKPE-QRYKLGALLVNGLRICATT--SGTTHVP---TTSTETKLRREQERLTVRILQILRAFMHNEERKLPADWEVRTTEFRVKKGLRNISDIQTTLNSFELVKHALPHLASTSSLVAKEVLSLLGMMLFNANERVQESMLNYFLHTKEEVFFYAVRNRLQMSTANIKERRLLISQQKARQSEAK--SQAENLRATMTLGIKALQQIKQYRIEMKIEQANNDL--------TRRVSLTKMQSQSMMT--KRRKESGSQTP-------SNSSGKKSGGSGNKKVAFANGLKGESQEPMAQSLLEESASSDSGAEVENLASQTHDEDETIS-MKDDGY--IALVLKVLASICDGQHFGLQNYLREQPDNIKSFNIVAEVSQFINVAYSNINGDTIDLLIQLFSTVNEFCAGNQENRATVYDNKIIDYINFILRSSDF-ESCEPQQVVQLRQTIANLVISLIEENSPEALVIAREVKDTLDKGALYRAMSECYEAQQRTGKDGGFLVRLFKKEENRELKEAMYEVGFTFYVILARLYDIDPAMGKKDSDPYGRELQISDIQQKAFKFFKKNAMTIEILKNDNLQKVHFRVRNKNVLREELKEKLKWNVDRSSPSTKIRDFMDWTKAILKDIHYQKKVLSNPFTILLTRLWLIWNHAATLTAVIINLI 2328          

HSP 2 Score: 198.364 bits (503), Expect = 1.772e-46
Identity = 130/282 (46.10%), Postives = 186/282 (65.96%), Query Frame = 3
Query: 7137 LYEISLLLSMSIGGIWIPYLYVFHLFNVIHNNQLLKGVIASVTKNGRXXXXXXXXXXXXXXXFSIFAFCFLRSTFSSENYLYADTLVQTFVSLVRFGIVGDLYQYTIPHKYYMKTVDTAFTEFSXXXXXXXXXXXXXXXXXXXXXXXXXVDTFSELRDLKYKTEKDMKETCFICSRAGHDFDQSSSSFEHHVVYEHNMWAYLFYFLHLKEIKINDYFHLDLYVANMLKRENYDFFPINCALSLTAEQEKY--SRIDEISRNVKIIVSNRQNEEREKLRRTNL 7976
            LY +S       G  + PY + FHL N+++NNQLL+GVI +VT NG  LIWV +L + +MY+FS+ AF  LR  F     ++   L Q FV+++RFG++GDL++  +P     +     F  F  + IF + FFI IT  GLNIIFGIIVDTFSELR++K+  E DM++ CFICSR+ +DF+     F++HV  EHNMWAY+F+F+HL++   NDY  L+L+V  +L  E YDFFP+N AL L+A+ E    S+IDE+ ++VK +V +++ EE E+ R   L
Sbjct: 2443 LYYLSFAACAFAGTFYCPYFFAFHLLNMVNNNQLLQGVIQAVTMNGLSLIWVSVLGIAIMYLFSVLAFARLRRGFGG--LMFCSDLSQCFVTVLRFGLIGDLFENMVP-----REDSPTFDSFFWMAIFHIVFFILITTVGLNIIFGIIVDTFSELRNMKWTAEVDMRDNCFICSRSNYDFEHHGQGFDYHVRNEHNMWAYIFFFIHLQDTAKNDYTSLELHVYKLLIEEKYDFFPMNRALCLSAKDEDSTESKIDELLQHVKNLVQHQKEEEAERKRWAEL 2717          
BLAST of Inositol 1,4,5-trisphosphate receptor type 3 vs. TrEMBL
Match: A0A1S3H9B8 (inositol 1,4,5-trisphosphate receptor type 3 isoform X13 OS=Lingula unguis OX=7574 GN=LOC106152615 PE=4 SV=1)

HSP 1 Score: 1139.41 bits (2946), Expect = 0.000e+0
Identity = 744/2312 (32.18%), Postives = 1230/2312 (53.20%), Query Frame = 2
Query:  164 MNDYLSYGDRICLYCEETNGFINSNNSSSHYNELRIFSKQDKFNPENVSDIQEIIFEVVIQNRXXXXXXXXXXXXDINNKSENLELKIQAEQAKATVISEENDNALENRRNLGKTVHYGDVIQLRHVYTRKYIHVNIAKTSSKDQNSMILNLQSHNLKSAQFKIVPRYKVKYEGEPVQFMDLVTFESLKAPSHYFHASDLYQIDNFFHGAALNLATEQSGFTLIK--SASDTHIMEEDNFLRGGDYIQIIHKEIDGYIESEGIQGGMKKADIYLRIRKSDKFQTLTNSRLSSSANTFWQVEIEKVRLSTEIGQWSSNFRFRHATNRLYLSVKKDLSVSMTKNATNPNTVFRLYPQNIDKLIIPYGRYFRMEHVLTGTWIHANKEQVYVKPNQSKYDDAAE--KCLGNLKYETNELRELFCVHQRLYDDAFVVFKVPTEIVESFNLLSGYFPLIKNLIVDRKKAVPFTASQSYRYKLALEEIRDSLYLDGKPHSLRQKHLRNLQIVDLLVELVLLPFHSKIDAAFTEKIYRASFEILHNYMKGSSIKNSLYFAKYINLFEPKMLENNDLGHKIIEMIAELLRNNQKVLECISFQEIFPFIDNLRINQNFRYLEYLETFCVCNGEPMTQNQIKIAVKWLSEDQRGVFLTDRGQNLNLESNVIYIKTKLDSNWMKLHEFLDITAQIDQENNPLYHQDNKDYFLKQMDLLLALCYGRNQYCTNLIINKLNYISWEQCFAAINSPMIPPYMKTKYFEIIQTMFIDIGRNYAVIESPKFNFIFNQIQG-------DSSVAVECMFPTPSESVTIKIFKDLSEWIYNFLESTPRMISSNKDFNYLIRIVFITINKLIQYGYYDSPSLDRI-CKSLLKLLNGRNDLPFEYDSKKESLKIRKKLVTKYKNISRYEDSEETRAIVAAKLSGLEILDSILIYERVSVVAKLISRFKKCVQPDLKVQKKRLTGHTHLEACLSNGFDVAQQYKQSNRATKKMVSEIDNLFTTARFLDSEPWTNILIDLAHYQNEMMTQKSLLILHKLYSIKESSFQDTYATFISKTKQSQDLQELMCEYIPALRLHTKSLIGPPDLEKIAAMITEMINVCKIPKSDSF-NPISQRIIVGYGILD-----IAMETIAQIYRSFDRSKMMYGASEVISLITNLLRHLAISNPSFQEXXXXXXXXXXXXYEHSPPAELADLLRCGLFHNNRTFCGTLKSFQINKIVLMVADTARKNPLVGAAFIHLLESIVAVNNGEVPLKRNQLMVMKFVMKSFNQLVYILDSKSMSRVDLLTIHSASNDAFYFTKVIDLFIACCQGENQYVQSLCQTIMPLDELFDLLTHNDISIIYKRGLLKYFSKVYLSRTNISNQEGIIKNFIESKYCGEILDSIERTTLLTQIILDKTEHFNLLPILKKEFILKPPTEFQVSE----NIQMHLHYIIFGSSI--FMASLCSAFSIMEISPAPELMKVIKSINH---ITMDIFSQMWKFQLHPSVFSVITESVLQIIS----------YTDTSDLEAKTMALQHCKPQIMDF------------DPRKEIDNLYT----EEIELNLKLQTFIFNCSQLIAGQNTVKAQIKANLRKQYVNLLDQNALPLNLEYQNHLKCFINNSYQKGEIRRYKLVDILIRQLEISGSVERNGKRHTKLDRNSFSKTIKRLDQDALDLRSLQILRGLIYNEECLLPDNWELKIFNSSVQDILKCIKNVQNCLNKLNLSSRTQIHMVNSCDLVKREAITLQSAMLMNANKNVQESLLRYFKGAQEEVFFSAIKYQLQNAFTDLKDQKLMLSQKKSFGDIEKYTCHESDLRIDNLAHILYQQLAEYEIRYEDQNRSLAINRYAYTTTKESFTTRHMRQIYTPAKMKS----EINSSSPLICCPRNSSKSNYDMR------STDKSDSLFKNNLQDEYELKSVVTKESNSSTDKTIENSAWIKGETLDLMRNDPHQNVKLILQLLSRMCVGQYQGLQNYLRIQPDNRSSVDVISLIVQFLGNIYANVRQSTIDLSIQAFDTIKETIMGNQENRSVVYRAKVVDYANFILRNDEISETCDPNNVLQMFLVIGRVIMALIEENGREETELAKEIQITLDIKAVFKIMTRCL--------------------------------DMMEDTKRKLIKNKIYDVGFTYFLILARLEDL---CNGKLLKHFQISDQQMKAXXXXXXGSASVEILKGDQLQRIHFRLKHKEVLRESVKEKVKWEVDRTTPSNKIRSFISWSKLILPDMNFQRKIIQNPLLLFVTKQWNAMNYFLTLLSLVINIL 6805
            M ++L  GD I L+CEET G++ S  +SS +N L I+  QD+  P  + +   I F V IQNRYKL KKY K     +   ENLELK    QAK +  +E  DN  E +R  GK V YG++IQL+HV+T KY+H++  +TS +D+N+M+++L  +N K AQF+I+PRYKVK EGE VQ +D + +ES K+  HYFH+S  + I+    G+ LNL   Q+GFT+++    SD    E +  +RG  +I++ HKE++ Y+ +EG+ G   + +++LRIR+ D+    T S   +SA T+WQVE E   L+  + +W    R RH T R +L +  D  V +T    +P +VFR +P   ++  I +  Y R+EHVLTG W+HA K++    P Q + D   E  + +  L+++  E+R++     R Y D F + +V  E + S N ++G  P +  LI  R++     A ++++   AL+E++  + ++G+ +   QK +RN +IVDLLV+L+  P     D+ +   +++ +++IL+ YM G+S KN+LYFAKYI  F+ ++    D+G  + +M+ EL+R+N+++++ I+ ++I  F+D LR  +N+R+L+ L   CVC+G+ + +NQ  I   WL  D+  V+L +RGQ ++ E NV+YI T     W+ LH+F +        ++P Y ++   Y  +Q+DLL  LC GRNQ+   +I   L+ ++WE  F  + S ++PP ++ KY  +I  +F+D+G +++V++     F++  I          S VA   +F          + +D   WI  F+ES P M SS    N LI  V   +  L+++G Y S    RI  K L+ +L+GRND PF  +++ ++ K  KKLV +Y+   R+E S ET+A+V AK  GL +L+ +  ++  + +   +S+FK     +     K+    + L   + + +D     K++ R  KK + E+  +F ++ + D E  TNI +DL++Y+ E M  +SL IL+K YS K   F+    T +  T++S  +   +   +P +R   K        E ++ +  + +    +    +  +P++Q+I++ +G+LD     ++ E   QI       ++++G +       NLLR LA  N   Q  + + LD+L+++     P+ LA  LR  +F  N+  C  ++  QI KIV +  +   + P     F+ LL SIV V   E+PLKRNQ +VMK++M+++++  Y+ D     R+ +LT  + ++   Y   ++DL   C +GEN+Y++SLCQTIMP++E+ D+L ++ I    K   L+Y   VY+       + G   +    ++    + ++ R     +  + + E      +   E +  PP +  V+E    +   H     F  ++  F+ +  + F   +    P+ ++ +  + H   +  D    +     H  V      SVLQ  S           T+   L+ K + L     ++M+             DP +E  + YT     E ELN K + F  NCS +  G NTV AQ+K   +++Y  +     LPL  E+Q H++CF+ ++ +K   +RY+ V  L++QL +S               N+ +      + D LD++SLQILR +I+NEE  L ++WE    +  VQ  LK I  VQN LN  +       H+    + + RE++   S ML NAN+NVQ ++L  FK  + E FF AI+ +L+ A   LK+++ + +Q            HE+ ++             E   + +    +L + R A    +    +R   ++   A+  S    + +  S L      SSK N   R      S ++   L   +  ++ EL  V+ + S++ +    E+      + LD +       + L+L+LL+ MC GQ Q +Q+YLR QPDN  S++V++   QF+  +Y+N+  STIDL IQ F T+ E   GNQ NR V+   KVVDY NFILR  +  E       L++  VI  ++++LIEENG E  ++A+E++ T+D +AV++ M  C                                 ++ME  K+  +K+K Y+VGF YFL++AR  D+    N K      I+  QM A+ ++KK S S+E++K   LQ++HFR+K+K VLRE VKEK+KW+VDR++PSNKIR  ++WSK IL D+ +QRK+++NP+ +F TK W   NY + LLS+ IN+L
Sbjct:    1 MGEFLCIGDYISLFCEETEGYVYSYQTSSSHNGLYIYQGQDRKKPGKIPNPHAITFRVCIQNRYKLNKKYRKLLAASSKDPENLELKALVAQAKTSANAENQDNISEQKRQHGKRVRYGEIIQLKHVFTDKYVHISTTQTSHRDKNNMLISLHQYNGKHAQFRILPRYKVKSEGEYVQILDQIVYESFKSQGHYFHSSVPWNIEKDMVGSELNLGVAQTGFTVVRYYRPSD----ENEANVRGSSFIRLFHKELEAYLVAEGLFGEPVQEEVHLRIREIDQLNPRTLSP-PNSAITYWQVEPEDTILNGGVVRWEQQVRLRHVTTRRFLCLDADFEVCLTAEENDPRSVFRFHPVLSEQNEIDFESYCRIEHVLTGNWLHALKDE----PYQRRRDMGRENDRSMQALRWDGGEVRKISSTENRRYVDVFTIHEVEWEQIYSANFVAGMVPFLSKLIESREECDYLNAMKTHQITTALQELKQFMIINGETYKDHQKLMRNFRIVDLLVQLLQSPLQDAPDSNYLLSVFKEAYDILYTYMTGNSRKNALYFAKYIEFFQTQLSLKGDIGLNVAQMLVELIRDNRQIVDRITHEQIDIFVDLLRQRKNYRFLDLLNVLCVCDGKTILENQSYITETWLRHDKADVYLIERGQYIHKEHNVVYISTDAGHTWVPLHQFANA-------DSPYYSEEEYLYLDRQLDLLGKLCKGRNQFSIRVITKDLDILTWENTFVCLRSELLPPSLRAKYCSLIIDLFVDVGASHSVLDQHTLVFVYEDIDNPRPLYSTKSQVATNVLFLAQELGTVFPVMRD---WIQEFVESNPEMYSSQVGQNKLIEQVMRLLCYLVRFGCYCSADEIRILLKPLMIMLDGRNDRPFPKNAEIQNSKEVKKLVKQYRETDRFEKSAETKALVDAKYQGLSVLELLFTFQSNTRLESFVSKFKTA---ETTANAKKKKHRSVLSPLVDDSYDAFNTSKKNLRKQKKFLHELRAMFESSSYFDVEYITNISLDLSNYKYEKMLTQSLNILNKYYSSKTDMFKIAIPTLVLTTQESCKIHIDIMRQLPLVRHLAKCSYNMEQAEAMSVVFDQFVLFTHLRDEPTLRHPMNQKILINHGVLDLIFAILSQEVDVQITEQAAPMELVFGKA------LNLLRFLAQGNEDVQAKMNDRLDSLMNI--KLVPSHLAIALR-EVFAGNQNNCLKIQPKQILKIVHLAGENQDRAP----EFLDLLGSIVKVELLELPLKRNQGLVMKYLMQNYHKAAYLFDQSQEDRLRILTSKTGNSHQRYLISLVDLLAKCAEGENRYIESLCQTIMPIEEIMDVLNNHFIDNNLKSPYLRYLMWVYMKTAGTMIESG-AGDLPHDRHVWIYIQALAREAESLKTYISENE------VKTVEVMRAPPPKGAVAEMDDSDGAAHATLFYFFDAVLPFLQTFFTKFYSPDKELYPDELEYVDQLAHSLVLWCDRVGAVLCNATHLKVLIGCVPSVLQSSSIPKNLSTESALTNYPSLKPKQVQLWKNTYKVMEGFIEQYGNGRCLRDPTRETIDTYTIYYQNEDELNKKFRAFSVNCSLVYGGHNTVTAQLKHKSKREYTEIGGDEDLPLGEEFQAHVRCFVKHN-EKNIAKRYQNVSKLVQQLAVSA--------------NAVNPKDGTYENDELDIKSLQILRAVIHNEERKLREDWEENTQDKKVQKQLKVILEVQNTLNSYSAVEEVLPHLGRPSNAIVRESLAFLSIMLFNANRNVQRTMLDVFKSMRTETFFFAIRIRLEIAANGLKERRALATQ------------HEARVK-------------ESMTQAKSLQTNLTVGRKAMKDIQAIERSRRQSRLMKGARANSLRALQRDRQSGLTSISPASSKCNSLQRFKLPNGSLNEETPLVFGSNHNDIELNEVMVEGSDNLSVDVEED------DVLDGLEFKDEGYIVLVLRLLAAMCDGQNQSIQDYLRDQPDNIKSINVVADTAQFVNVVYSNITASTIDLVIQLFSTLNEFTAGNQANRVVLLDNKVVDYINFILRAGKY-EGISMEMQLELREVIANLLVSLIEENGPEPIKVAREVKDTVDKEAVYRCMVDCYSIHQPPTYKAKISTNMGDNMKNLSQMGGGLLREIMEKNKKNDLKDKAYEVGFLYFLLMARFYDIDPVLNEK--AGLVITPDQMAAYNYYKKNSMSIELMKDGNLQKVHFRVKNKNVLREEVKEKLKWDVDRSSPSNKIRDLMAWSKDILKDIYYQRKMLRNPIAVFFTKFWLLWNYLVILLSVAINVL 2221          

HSP 2 Score: 203.371 bits (516), Expect = 2.590e-49
Identity = 123/274 (44.89%), Postives = 188/274 (68.61%), Query Frame = 3
Query: 7152 LLLSMSIGGIWI-PYLYVFHLFNVIHNNQLLKGVIASVTKNGRXXXXXXXXXXXXXXXFSIFAFCFLRSTFSSENYLYADTLVQTFVSLVRFGIVGDLY-QYTIPHKYYMKTVDTAFTEFSXXXXXXXXXXXXXXXXXXXXXXXXXVDTFSELRDLKYKTEKDMKETCFICSRAGHDFDQSSSSFEHHVVYEHNMWAYLFYFLHLKEIKINDYFHLDLYVANMLKRENYDFFPINCALSLTAEQEKYS-RIDEISRNVKIIVSNRQNEEREKLR 7964
            + + MS+ G +   Y + FHL N+++NNQ+L+GVI +VT+NG  L+WV IL VI+ YI+++ +F F+R+ F  ++  Y  TL++  V+++R+G++G ++ + T+P        +  F  F+++ +F L FFI IT  GLN+I GI+VDTFSELRDLK+  E DM++TCFICSR  HDF+   + F  H   EHNMWAY+F+F+HL + K NDY  LDL+VA  L+RE Y+FFP+NCALSLT E++    +ID +   V  ++  ++ EE +++R
Sbjct: 2342 IFVGMSVAGTFFHGYFFAFHLLNIVNNNQILQGVIKAVTQNGVSLLWVGILGVIIFYIYALISFAFMRALFLPKDEEYCGTLLECSVTVIRYGLIGAIFDRLTLPES------ENNFIAFAVVAVFHLSFFILITTIGLNVILGIVVDTFSELRDLKWTAESDMRDTCFICSRGSHDFEHHGNGFLKHAREEHNMWAYIFFFIHLDDTKSNDYTALDLHVAQALQREQYEFFPMNCALSLTGEEDGTDEKIDAVLEKVTELLRRQREEESKRMR 2609          

HSP 3 Score: 25.7942 bits (55), Expect = 2.590e-49
Identity = 22/89 (24.72%), Postives = 40/89 (44.94%), Query Frame = 1
Query: 6919 IFREVVMGLGVSHAVIAFLILITYLITDR---PTLRTIRSYASRIKQRMVSFYKKEDEN------DSEKMVDGTNQLVSLFSFMRFLYC 7158
            I+  ++  +G +H + +  +LI+Y +++    P+L  I +   R+  R     K E+E+      D EK    +   V  FS   F Y 
Sbjct: 2258 IYDLLLYAMGGTHNLFSLFVLISYFLSNHPKCPSLSAIPNLCRRLCGR-----KDEEEDEIAHEVDCEKAKRQSKLDVKFFSLATFYYV 2341          
BLAST of Inositol 1,4,5-trisphosphate receptor type 3 vs. TrEMBL
Match: A0A1S3H6W6 (inositol 1,4,5-trisphosphate receptor type 3 isoform X11 OS=Lingula unguis OX=7574 GN=LOC106152615 PE=4 SV=1)

HSP 1 Score: 1135.55 bits (2936), Expect = 0.000e+0
Identity = 746/2323 (32.11%), Postives = 1232/2323 (53.03%), Query Frame = 2
Query:  164 MNDYLSYGDRICLYCEETNGFINSNNSSSHYNELRIFSKQDKFNPENVSDIQEIIFEVVIQNRXXXXXXXXXXXXDINNKSENLELKIQAEQAKATVISEENDNALENRRNLGKTVHYGDVIQLRHVYTRKYIHVNIAKTSSKDQNSMILNLQSHNLKSAQFKIVPRYKVKYEGEPVQFMDLVTFESLKAPSHYFHASDLYQIDNFFHGAALNLATEQSGFTLIK--SASDTHIMEEDNFLRGGDYIQIIHKEIDGYIESEGIQGGMKKADIYLRIRKSDKFQTLTNSRLSSSANTFWQVEIEKVRLSTEIGQWSSNFRFRHATNRLYLSVKKDLSVSMTKNATNPNTVFRLYP------QNIDKLI-----IPYGRYFRMEHVLTGTWIHANKEQVYVKPNQSKYDDAAE--KCLGNLKYETNELRELFCVHQRLYDDAFVVFKVPTEIVESFNLLSGYFPLIKNLIVDRKKAVPFTASQSYRYKLALEEIRDSLYLDGKPHSLRQKHLRNLQIVDLLVELVLLPFHSKIDAAFTEKIYRASFEILHNYMKGSSIKNSLYFAKYINLFEPKMLENNDLGHKIIEMIAELLRNNQKVLECISFQEIFPFIDNLRINQNFRYLEYLETFCVCNGEPMTQNQIKIAVKWLSEDQRGVFLTDRGQNLNLESNVIYIKTKLDSNWMKLHEFLDITAQIDQENNPLYHQDNKDYFLKQMDLLLALCYGRNQYCTNLIINKLNYISWEQCFAAINSPMIPPYMKTKYFEIIQTMFIDIGRNYAVIESPKFNFIFNQIQG-------DSSVAVECMFPTPSESVTIKIFKDLSEWIYNFLESTPRMISSNKDFNYLIRIVFITINKLIQYGYYDSPSLDRI-CKSLLKLLNGRNDLPFEYDSKKESLKIRKKLVTKYKNISRYEDSEETRAIVAAKLSGLEILDSILIYERVSVVAKLISRFKKCVQPDLKVQKKRLTGHTHLEACLSNGFDVAQQYKQSNRATKKMVSEIDNLFTTARFLDSEPWTNILIDLAHYQNEMMTQKSLLILHKLYSIKESSFQDTYATFISKTKQSQDLQELMCEYIPALRLHTKSLIGPPDLEKIAAMITEMINVCKIPKSDSF-NPISQRIIVGYGILD-----IAMETIAQIYRSFDRSKMMYGASEVISLITNLLRHLAISNPSFQEXXXXXXXXXXXXYEHSPPAELADLLRCGLFHNNRTFCGTLKSFQINKIVLMVADTARKNPLVGAAFIHLLESIVAVNNGEVPLKRNQLMVMKFVMKSFNQLVYILDSKSMSRVDLLTIHSASNDAFYFTKVIDLFIACCQGENQYVQSLCQTIMPLDELFDLLTHNDISIIYKRGLLKYFSKVYLSRTNISNQEGIIKNFIESKYCGEILDSIERTTLLTQIILDKTEHFNLLPILKKEFILKPPTEFQVSE----NIQMHLHYIIFGSSI--FMASLCSAFSIMEISPAPELMKVIKSINH---ITMDIFSQMWKFQLHPSVFSVITESVLQIIS----------YTDTSDLEAKTMALQHCKPQIMDF------------DPRKEIDNLYT----EEIELNLKLQTFIFNCSQLIAGQNTVKAQIKANLRKQYVNLLDQNALPLNLEYQNHLKCFINNSYQKGEIRRYKLVDILIRQLEISGSVERNGKRHTKLDRNSFSKTIKRLDQDALDLRSLQILRGLIYNEECLLPDNWELKIFNSSVQDILKCIKNVQNCLNKLNLSSRTQIHMVNSCDLVKREAITLQSAMLMNANKNVQESLLRYFKGAQEEVFFSAIKYQLQNAFTDLKDQKLMLSQKKSFGDIEKYTCHESDLRIDNLAHILYQQLAEYEIRYEDQNRSLAINRYAYTTTKESFTTRHMRQIYTPAKMKS----EINSSSPLICCPRNSSKSNYDMR------STDKSDSLFKNNLQDEYELKSVVTKESNSSTDKTIENSAWIKGETLDLMRNDPHQNVKLILQLLSRMCVGQYQGLQNYLRIQPDNRSSVDVISLIVQFLGNIYANVRQSTIDLSIQAFDTIKETIMGNQENRSVVYRAKVVDYANFILRNDEISETCDPNNVLQMFLVIGRVIMALIEENGREETELAKEIQITLDIKAVFKIMTRCL--------------------------------DMMEDTKRKLIKNKIYDVGFTYFLILARLEDL---CNGKLLKHFQISDQQMKAXXXXXXGSASVEILKGDQLQRIHFRLKHKEVLRESVKEKVKWEVDRTTPSNKIRSFISWSKLILPDMNFQRKIIQNPLLLFVTKQWNAMNYFLTLLSLVINIL 6805
            M ++L  GD I L+CEET G++ S  +SS +N L I+  QD+  P  + +   I F V IQNRYKL KKY K     +   ENLELK    QAK +  +E  DN  E +R  GK V YG++IQL+HV+T KY+H++  +TS +D+N+M+++L  +N K AQF+I+PRYKVK EGE VQ +D + +ES K+  HYFH+S  + I+    G+ LNL   Q+GFT+++    SD    E +  +RG  +I++ HKE++ Y+ +EG+ G   + +++LRIR+ D+    T S   +SA T+WQVE E   L+  + +W    R RH T R +L +  D  V +T    +P +VFR +P      Q++D        I +  Y R+EHVLTG W+HA K++    P Q + D   E  + +  L+++  E+R++     R Y D F + +V  E + S N ++G  P +  LI  R++     A ++++   AL+E++  + ++G+ +   QK +RN +IVDLLV+L+  P     D+ +   +++ +++IL+ YM G+S KN+LYFAKYI  F+ ++    D+G  + +M+ EL+R+N+++++ I+ ++I  F+D LR  +N+R+L+ L   CVC+G+ + +NQ  I   WL  D+  V+L +RGQ ++ E NV+YI T     W+ LH+F +        ++P Y ++   Y  +Q+DLL  LC GRNQ+   +I   L+ ++WE  F  + S ++PP ++ KY  +I  +F+D+G +++V++     F++  I          S VA   +F          + +D   WI  F+ES P M SS    N LI  V   +  L+++G Y S    RI  K L+ +L+GRND PF  +++ ++ K  KKLV +Y+   R+E S ET+A+V AK  GL +L+ +  ++  + +   +S+FK     +     K+    + L   + + +D     K++ R  KK + E+  +F ++ + D E  TNI +DL++Y+ E M  +SL IL+K YS K   F+    T +  T++S  +   +   +P +R   K        E ++ +  + +    +    +  +P++Q+I++ +G+LD     ++ E   QI       ++++G +       NLLR LA  N   Q  + + LD+L+++     P+ LA  LR  +F  N+  C  ++  QI KIV +  +   + P     F+ LL SIV V   E+PLKRNQ +VMK++M+++++  Y+ D     R+ +LT  + ++   Y   ++DL   C +GEN+Y++SLCQTIMP++E+ D+L ++ I    K   L+Y   VY+       + G   +    ++    + ++ R     +  + + E      +   E +  PP +  V+E    +   H     F  ++  F+ +  + F   +    P+ ++ +  + H   +  D    +     H  V      SVLQ  S           T+   L+ K + L     ++M+             DP +E  + YT     E ELN K + F  NCS +  G NTV AQ+K   +++Y  +     LPL  E+Q H++CF+ ++ +K   +RY+ V  L++QL +S               N+ +      + D LD++SLQILR +I+NEE  L ++WE    +  VQ  LK I  VQN LN  +       H+    + + RE++   S ML NAN+NVQ ++L  FK  + E FF AI+ +L+ A   LK+++ + +Q            HE+ ++             E   + +    +L + R A    +    +R   ++   A+  S    + +  S L      SSK N   R      S ++   L   +  ++ EL  V+ + S++ +    E+      + LD +       + L+L+LL+ MC GQ Q +Q+YLR QPDN  S++V++   QF+  +Y+N+  STIDL IQ F T+ E   GNQ NR V+   KVVDY NFILR  +  E       L++  VI  ++++LIEENG E  ++A+E++ T+D +AV++ M  C                                 ++ME  K+  +K+K Y+VGF YFL++AR  D+    N K      I+  QM A+ ++KK S S+E++K   LQ++HFR+K+K VLRE VKEK+KW+VDR++PSNKIR  ++WSK IL D+ +QRK+++NP+ +F TK W   NY + LLS+ IN+L
Sbjct:    1 MGEFLCIGDYISLFCEETEGYVYSYQTSSSHNGLYIYQGQDRKKPGKIPNPHAITFRVCIQNRYKLNKKYRKLLAASSKDPENLELKALVAQAKTSANAENQDNISEQKRQHGKRVRYGEIIQLKHVFTDKYVHISTTQTSHRDKNNMLISLHQYNGKHAQFRILPRYKVKSEGEYVQILDQIVYESFKSQGHYFHSSVPWNIEKDMVGSELNLGVAQTGFTVVRYYRPSD----ENEANVRGSSFIRLFHKELEAYLVAEGLFGEPVQEEVHLRIREIDQLNPRTLSP-PNSAITYWQVEPEDTILNGGVVRWEQQVRLRHVTTRRFLCLDADFEVCLTAEENDPRSVFRFHPVLSLREQDLDPDTPEQNEIDFESYCRIEHVLTGNWLHALKDE----PYQRRRDMGRENDRSMQALRWDGGEVRKISSTENRRYVDVFTIHEVEWEQIYSANFVAGMVPFLSKLIESREECDYLNAMKTHQITTALQELKQFMIINGETYKDHQKLMRNFRIVDLLVQLLQSPLQDAPDSNYLLSVFKEAYDILYTYMTGNSRKNALYFAKYIEFFQTQLSLKGDIGLNVAQMLVELIRDNRQIVDRITHEQIDIFVDLLRQRKNYRFLDLLNVLCVCDGKTILENQSYITETWLRHDKADVYLIERGQYIHKEHNVVYISTDAGHTWVPLHQFANA-------DSPYYSEEEYLYLDRQLDLLGKLCKGRNQFSIRVITKDLDILTWENTFVCLRSELLPPSLRAKYCSLIIDLFVDVGASHSVLDQHTLVFVYEDIDNPRPLYSTKSQVATNVLFLAQELGTVFPVMRD---WIQEFVESNPEMYSSQVGQNKLIEQVMRLLCYLVRFGCYCSADEIRILLKPLMIMLDGRNDRPFPKNAEIQNSKEVKKLVKQYRETDRFEKSAETKALVDAKYQGLSVLELLFTFQSNTRLESFVSKFKTA---ETTANAKKKKHRSVLSPLVDDSYDAFNTSKKNLRKQKKFLHELRAMFESSSYFDVEYITNISLDLSNYKYEKMLTQSLNILNKYYSSKTDMFKIAIPTLVLTTQESCKIHIDIMRQLPLVRHLAKCSYNMEQAEAMSVVFDQFVLFTHLRDEPTLRHPMNQKILINHGVLDLIFAILSQEVDVQITEQAAPMELVFGKA------LNLLRFLAQGNEDVQAKMNDRLDSLMNI--KLVPSHLAIALR-EVFAGNQNNCLKIQPKQILKIVHLAGENQDRAP----EFLDLLGSIVKVELLELPLKRNQGLVMKYLMQNYHKAAYLFDQSQEDRLRILTSKTGNSHQRYLISLVDLLAKCAEGENRYIESLCQTIMPIEEIMDVLNNHFIDNNLKSPYLRYLMWVYMKTAGTMIESG-AGDLPHDRHVWIYIQALAREAESLKTYISENE------VKTVEVMRAPPPKGAVAEMDDSDGAAHATLFYFFDAVLPFLQTFFTKFYSPDKELYPDELEYVDQLAHSLVLWCDRVGAVLCNATHLKVLIGCVPSVLQSSSIPKNLSTESALTNYPSLKPKQVQLWKNTYKVMEGFIEQYGNGRCLRDPTRETIDTYTIYYQNEDELNKKFRAFSVNCSLVYGGHNTVTAQLKHKSKREYTEIGGDEDLPLGEEFQAHVRCFVKHN-EKNIAKRYQNVSKLVQQLAVSA--------------NAVNPKDGTYENDELDIKSLQILRAVIHNEERKLREDWEENTQDKKVQKQLKVILEVQNTLNSYSAVEEVLPHLGRPSNAIVRESLAFLSIMLFNANRNVQRTMLDVFKSMRTETFFFAIRIRLEIAANGLKERRALATQ------------HEARVK-------------ESMTQAKSLQTNLTVGRKAMKDIQAIERSRRQSRLMKGARANSLRALQRDRQSGLTSISPASSKCNSLQRFKLPNGSLNEETPLVFGSNHNDIELNEVMVEGSDNLSVDVEED------DVLDGLEFKDEGYIVLVLRLLAAMCDGQNQSIQDYLRDQPDNIKSINVVADTAQFVNVVYSNITASTIDLVIQLFSTLNEFTAGNQANRVVLLDNKVVDYINFILRAGKY-EGISMEMQLELREVIANLLVSLIEENGPEPIKVAREVKDTVDKEAVYRCMVDCYSIHQPPTYKAKISTNMGDNMKNLSQMGGGLLREIMEKNKKNDLKDKAYEVGFLYFLLMARFYDIDPVLNEK--AGLVITPDQMAAYNYYKKNSMSIELMKDGNLQKVHFRVKNKNVLREEVKEKLKWDVDRSSPSNKIRDLMAWSKDILKDIYYQRKMLRNPIAVFFTKFWLLWNYLVILLSVAINVL 2232          

HSP 2 Score: 203.371 bits (516), Expect = 2.908e-49
Identity = 123/274 (44.89%), Postives = 188/274 (68.61%), Query Frame = 3
Query: 7152 LLLSMSIGGIWI-PYLYVFHLFNVIHNNQLLKGVIASVTKNGRXXXXXXXXXXXXXXXFSIFAFCFLRSTFSSENYLYADTLVQTFVSLVRFGIVGDLY-QYTIPHKYYMKTVDTAFTEFSXXXXXXXXXXXXXXXXXXXXXXXXXVDTFSELRDLKYKTEKDMKETCFICSRAGHDFDQSSSSFEHHVVYEHNMWAYLFYFLHLKEIKINDYFHLDLYVANMLKRENYDFFPINCALSLTAEQEKYS-RIDEISRNVKIIVSNRQNEEREKLR 7964
            + + MS+ G +   Y + FHL N+++NNQ+L+GVI +VT+NG  L+WV IL VI+ YI+++ +F F+R+ F  ++  Y  TL++  V+++R+G++G ++ + T+P        +  F  F+++ +F L FFI IT  GLN+I GI+VDTFSELRDLK+  E DM++TCFICSR  HDF+   + F  H   EHNMWAY+F+F+HL + K NDY  LDL+VA  L+RE Y+FFP+NCALSLT E++    +ID +   V  ++  ++ EE +++R
Sbjct: 2353 IFVGMSVAGTFFHGYFFAFHLLNIVNNNQILQGVIKAVTQNGVSLLWVGILGVIIFYIYALISFAFMRALFLPKDEEYCGTLLECSVTVIRYGLIGAIFDRLTLPES------ENNFIAFAVVAVFHLSFFILITTIGLNVILGIVVDTFSELRDLKWTAESDMRDTCFICSRGSHDFEHHGNGFLKHAREEHNMWAYIFFFIHLDDTKSNDYTALDLHVAQALQREQYEFFPMNCALSLTGEEDGTDEKIDAVLEKVTELLRRQREEESKRMR 2620          

HSP 3 Score: 25.7942 bits (55), Expect = 2.908e-49
Identity = 22/89 (24.72%), Postives = 40/89 (44.94%), Query Frame = 1
Query: 6919 IFREVVMGLGVSHAVIAFLILITYLITDR---PTLRTIRSYASRIKQRMVSFYKKEDEN------DSEKMVDGTNQLVSLFSFMRFLYC 7158
            I+  ++  +G +H + +  +LI+Y +++    P+L  I +   R+  R     K E+E+      D EK    +   V  FS   F Y 
Sbjct: 2269 IYDLLLYAMGGTHNLFSLFVLISYFLSNHPKCPSLSAIPNLCRRLCGR-----KDEEEDEIAHEVDCEKAKRQSKLDVKFFSLATFYYV 2352          
BLAST of Inositol 1,4,5-trisphosphate receptor type 3 vs. TrEMBL
Match: A0A1S3H9B5 (inositol 1,4,5-trisphosphate receptor type 3 isoform X8 OS=Lingula unguis OX=7574 GN=LOC106152615 PE=4 SV=1)

HSP 1 Score: 1126.69 bits (2913), Expect = 0.000e+0
Identity = 746/2337 (31.92%), Postives = 1232/2337 (52.72%), Query Frame = 2
Query:  164 MNDYLSYGDRICLYCEETNGFINSNNSSSHYNELRIFSKQDKFNPENVSDIQEIIFEVVIQNRXXXXXXXXXXXXDINNKSENLELKIQAEQAKATVISEENDNALENRRNLGKTVHYGDVIQLRHVYTRKYIHVNIAKTSSKDQNSMILNLQSHNLKSAQFKIVPRYKVKYEGEPVQFMDLVTFESLKAPSHYFHASDLYQIDNFFHGAALNLATEQSGFTLIK--SASDTHIMEEDNFLRGGDYIQIIHKEIDGYIESEGIQGGMKKADIYLRIRKSDKFQTLTNSRLSSSANTFWQVEIEKVRLSTEIGQWSSNFRFRHATNRLYLSVKKDLSVSMTKNATNPNTVFRLYP------QNIDKLI-----IPYGRYFRMEHVLTGTWIHANKEQVYVKPNQSKYDDAAE--KCLGNLKYETNELRELFCVHQRLYDDAFVVFKVPTEIVESFNLLSGYFPLIKNLIVDRKKAVPFTASQSYRYKLALEEIRDSLYLDGKPHSLRQKHLRNLQIVDLLVELVLLPFHSKIDAAFTEKIYRASFEILHNYMKGSSIKNSLYFAKYINLFEPKMLENNDLGHKIIEMIAELLRNNQKVLECISFQEIFPFIDNLRINQNFRYLEYLETFCVCNGEPMTQNQIKIAVKWLSEDQ--------------RGVFLTDRGQNLNLESNVIYIKTKLDSNWMKLHEFLDITAQIDQENNPLYHQDNKDYFLKQMDLLLALCYGRNQYCTNLIINKLNYISWEQCFAAINSPMIPPYMKTKYFEIIQTMFIDIGRNYAVIESPKFNFIFNQIQG-------DSSVAVECMFPTPSESVTIKIFKDLSEWIYNFLESTPRMISSNKDFNYLIRIVFITINKLIQYGYYDSPSLDRI-CKSLLKLLNGRNDLPFEYDSKKESLKIRKKLVTKYKNISRYEDSEETRAIVAAKLSGLEILDSILIYERVSVVAKLISRFKKCVQPDLKVQKKRLTGHTHLEACLSNGFDVAQQYKQSNRATKKMVSEIDNLFTTARFLDSEPWTNILIDLAHYQNEMMTQKSLLILHKLYSIKESSFQDTYATFISKTKQSQDLQELMCEYIPALRLHTKSLIGPPDLEKIAAMITEMINVCKIPKSDSF-NPISQRIIVGYGILD-----IAMETIAQIYRSFDRSKMMYGASEVISLITNLLRHLAISNPSFQEXXXXXXXXXXXXYEHSPPAELADLLRCGLFHNNRTFCGTLKSFQINKIVLMVADTARKNPLVGAAFIHLLESIVAVNNGEVPLKRNQLMVMKFVMKSFNQLVYILDSKSMSRVDLLTIHSASNDAFYFTKVIDLFIACCQGENQYVQSLCQTIMPLDELFDLLTHNDISIIYKRGLLKYFSKVYLSRTNISNQEGIIKNFIESKYCGEILDSIERTTLLTQIILDKTEHFNLLPILKKEFILKPPTEFQVSE----NIQMHLHYIIFGSSI--FMASLCSAFSIMEISPAPELMKVIKSINH---ITMDIFSQMWKFQLHPSVFSVITESVLQIIS----------YTDTSDLEAKTMALQHCKPQIMDF------------DPRKEIDNLYT----EEIELNLKLQTFIFNCSQLIAGQNTVKAQIKANLRKQYVNLLDQNALPLNLEYQNHLKCFINNSYQKGEIRRYKLVDILIRQLEISGSVERNGKRHTKLDRNSFSKTIKRLDQDALDLRSLQILRGLIYNEECLLPDNWELKIFNSSVQDILKCIKNVQNCLNKLNLSSRTQIHMVNSCDLVKREAITLQSAMLMNANKNVQESLLRYFKGAQEEVFFSAIKYQLQNAFTDLKDQKLMLSQKKSFGDIEKYTCHESDLRIDNLAHILYQQLAEYEIRYEDQNRSLAINRYAYTTTKESFTTRHMRQIYTPAKMKS----EINSSSPLICCPRNSSKSNYDMR------STDKSDSLFKNNLQDEYELKSVVTKESNSSTDKTIENSAWIKGETLDLMRNDPHQNVKLILQLLSRMCVGQYQGLQNYLRIQPDNRSSVDVISLIVQFLGNIYANVRQSTIDLSIQAFDTIKETIMGNQENRSVVYRAKVVDYANFILRNDEISETCDPNNVLQMFLVIGRVIMALIEENGREETELAKEIQITLDIKAVFKIMTRCL--------------------------------DMMEDTKRKLIKNKIYDVGFTYFLILARLEDL---CNGKLLKHFQISDQQMKAXXXXXXGSASVEILKGDQLQRIHFRLKHKEVLRESVKEKVKWEVDRTTPSNKIRSFISWSKLILPDMNFQRKIIQNPLLLFVTKQWNAMNYFLTLLSLVINIL 6805
            M ++L  GD I L+CEET G++ S  +SS +N L I+  QD+  P  + +   I F V IQNRYKL KKY K     +   ENLELK    QAK +  +E  DN  E +R  GK V YG++IQL+HV+T KY+H++  +TS +D+N+M+++L  +N K AQF+I+PRYKVK EGE VQ +D + +ES K+  HYFH+S  + I+    G+ LNL   Q+GFT+++    SD    E +  +RG  +I++ HKE++ Y+ +EG+ G   + +++LRIR+ D+    T S   +SA T+WQVE E   L+  + +W    R RH T R +L +  D  V +T    +P +VFR +P      Q++D        I +  Y R+EHVLTG W+HA K++    P Q + D   E  + +  L+++  E+R++     R Y D F + +V  E + S N ++G  P +  LI  R++     A ++++   AL+E++  + ++G+ +   QK +RN +IVDLLV+L+  P     D+ +   +++ +++IL+ YM G+S KN+LYFAKYI  F+ ++    D+G  + +M+ EL+R+N+++++ I+ ++I  F+D LR  +N+R+L+ L   CVC+G+ + +NQ  I   WL  D+                V+L +RGQ ++ E NV+YI T     W+ LH+F +        ++P Y ++   Y  +Q+DLL  LC GRNQ+   +I   L+ ++WE  F  + S ++PP ++ KY  +I  +F+D+G +++V++     F++  I          S VA   +F          + +D   WI  F+ES P M SS    N LI  V   +  L+++G Y S    RI  K L+ +L+GRND PF  +++ ++ K  KKLV +Y+   R+E S ET+A+V AK  GL +L+ +  ++  + +   +S+FK     +     K+    + L   + + +D     K++ R  KK + E+  +F ++ + D E  TNI +DL++Y+ E M  +SL IL+K YS K   F+    T +  T++S  +   +   +P +R   K        E ++ +  + +    +    +  +P++Q+I++ +G+LD     ++ E   QI       ++++G +       NLLR LA  N   Q  + + LD+L+++     P+ LA  LR  +F  N+  C  ++  QI KIV +  +   + P     F+ LL SIV V   E+PLKRNQ +VMK++M+++++  Y+ D     R+ +LT  + ++   Y   ++DL   C +GEN+Y++SLCQTIMP++E+ D+L ++ I    K   L+Y   VY+       + G   +    ++    + ++ R     +  + + E      +   E +  PP +  V+E    +   H     F  ++  F+ +  + F   +    P+ ++ +  + H   +  D    +     H  V      SVLQ  S           T+   L+ K + L     ++M+             DP +E  + YT     E ELN K + F  NCS +  G NTV AQ+K   +++Y  +     LPL  E+Q H++CF+ ++ +K   +RY+ V  L++QL +S               N+ +      + D LD++SLQILR +I+NEE  L ++WE    +  VQ  LK I  VQN LN  +       H+    + + RE++   S ML NAN+NVQ ++L  FK  + E FF AI+ +L+ A   LK+++ + +Q            HE+ ++             E   + +    +L + R A    +    +R   ++   A+  S    + +  S L      SSK N   R      S ++   L   +  ++ EL  V+ + S++ +    E+      + LD +       + L+L+LL+ MC GQ Q +Q+YLR QPDN  S++V++   QF+  +Y+N+  STIDL IQ F T+ E   GNQ NR V+   KVVDY NFILR  +  E       L++  VI  ++++LIEENG E  ++A+E++ T+D +AV++ M  C                                 ++ME  K+  +K+K Y+VGF YFL++AR  D+    N K      I+  QM A+ ++KK S S+E++K   LQ++HFR+K+K VLRE VKEK+KW+VDR++PSNKIR  ++WSK IL D+ +QRK+++NP+ +F TK W   NY + LLS+ IN+L
Sbjct:    1 MGEFLCIGDYISLFCEETEGYVYSYQTSSSHNGLYIYQGQDRKKPGKIPNPHAITFRVCIQNRYKLNKKYRKLLAASSKDPENLELKALVAQAKTSANAENQDNISEQKRQHGKRVRYGEIIQLKHVFTDKYVHISTTQTSHRDKNNMLISLHQYNGKHAQFRILPRYKVKSEGEYVQILDQIVYESFKSQGHYFHSSVPWNIEKDMVGSELNLGVAQTGFTVVRYYRPSD----ENEANVRGSSFIRLFHKELEAYLVAEGLFGEPVQEEVHLRIREIDQLNPRTLSP-PNSAITYWQVEPEDTILNGGVVRWEQQVRLRHVTTRRFLCLDADFEVCLTAEENDPRSVFRFHPVLSLREQDLDPDTPEQNEIDFESYCRIEHVLTGNWLHALKDE----PYQRRRDMGRENDRSMQALRWDGGEVRKISSTENRRYVDVFTIHEVEWEQIYSANFVAGMVPFLSKLIESREECDYLNAMKTHQITTALQELKQFMIINGETYKDHQKLMRNFRIVDLLVQLLQSPLQDAPDSNYLLSVFKEAYDILYTYMTGNSRKNALYFAKYIEFFQTQLSLKGDIGLNVAQMLVELIRDNRQIVDRITHEQIDIFVDLLRQRKNYRFLDLLNVLCVCDGKTILENQSYITETWLRHDKVSFDAKTCHIHLTGADVYLIERGQYIHKEHNVVYISTDAGHTWVPLHQFANA-------DSPYYSEEEYLYLDRQLDLLGKLCKGRNQFSIRVITKDLDILTWENTFVCLRSELLPPSLRAKYCSLIIDLFVDVGASHSVLDQHTLVFVYEDIDNPRPLYSTKSQVATNVLFLAQELGTVFPVMRD---WIQEFVESNPEMYSSQVGQNKLIEQVMRLLCYLVRFGCYCSADEIRILLKPLMIMLDGRNDRPFPKNAEIQNSKEVKKLVKQYRETDRFEKSAETKALVDAKYQGLSVLELLFTFQSNTRLESFVSKFKTA---ETTANAKKKKHRSVLSPLVDDSYDAFNTSKKNLRKQKKFLHELRAMFESSSYFDVEYITNISLDLSNYKYEKMLTQSLNILNKYYSSKTDMFKIAIPTLVLTTQESCKIHIDIMRQLPLVRHLAKCSYNMEQAEAMSVVFDQFVLFTHLRDEPTLRHPMNQKILINHGVLDLIFAILSQEVDVQITEQAAPMELVFGKA------LNLLRFLAQGNEDVQAKMNDRLDSLMNI--KLVPSHLAIALR-EVFAGNQNNCLKIQPKQILKIVHLAGENQDRAP----EFLDLLGSIVKVELLELPLKRNQGLVMKYLMQNYHKAAYLFDQSQEDRLRILTSKTGNSHQRYLISLVDLLAKCAEGENRYIESLCQTIMPIEEIMDVLNNHFIDNNLKSPYLRYLMWVYMKTAGTMIESG-AGDLPHDRHVWIYIQALAREAESLKTYISENE------VKTVEVMRAPPPKGAVAEMDDSDGAAHATLFYFFDAVLPFLQTFFTKFYSPDKELYPDELEYVDQLAHSLVLWCDRVGAVLCNATHLKVLIGCVPSVLQSSSIPKNLSTESALTNYPSLKPKQVQLWKNTYKVMEGFIEQYGNGRCLRDPTRETIDTYTIYYQNEDELNKKFRAFSVNCSLVYGGHNTVTAQLKHKSKREYTEIGGDEDLPLGEEFQAHVRCFVKHN-EKNIAKRYQNVSKLVQQLAVSA--------------NAVNPKDGTYENDELDIKSLQILRAVIHNEERKLREDWEENTQDKKVQKQLKVILEVQNTLNSYSAVEEVLPHLGRPSNAIVRESLAFLSIMLFNANRNVQRTMLDVFKSMRTETFFFAIRIRLEIAANGLKERRALATQ------------HEARVK-------------ESMTQAKSLQTNLTVGRKAMKDIQAIERSRRQSRLMKGARANSLRALQRDRQSGLTSISPASSKCNSLQRFKLPNGSLNEETPLVFGSNHNDIELNEVMVEGSDNLSVDVEED------DVLDGLEFKDEGYIVLVLRLLAAMCDGQNQSIQDYLRDQPDNIKSINVVADTAQFVNVVYSNITASTIDLVIQLFSTLNEFTAGNQANRVVLLDNKVVDYINFILRAGKY-EGISMEMQLELREVIANLLVSLIEENGPEPIKVAREVKDTVDKEAVYRCMVDCYSIHQPPTYKAKISTNMGDNMKNLSQMGGGLLREIMEKNKKNDLKDKAYEVGFLYFLLMARFYDIDPVLNEK--AGLVITPDQMAAYNYYKKNSMSIELMKDGNLQKVHFRVKNKNVLREEVKEKLKWDVDRSSPSNKIRDLMAWSKDILKDIYYQRKMLRNPIAVFFTKFWLLWNYLVILLSVAINVL 2246          

HSP 2 Score: 203.371 bits (516), Expect = 2.744e-49
Identity = 123/274 (44.89%), Postives = 188/274 (68.61%), Query Frame = 3
Query: 7152 LLLSMSIGGIWI-PYLYVFHLFNVIHNNQLLKGVIASVTKNGRXXXXXXXXXXXXXXXFSIFAFCFLRSTFSSENYLYADTLVQTFVSLVRFGIVGDLY-QYTIPHKYYMKTVDTAFTEFSXXXXXXXXXXXXXXXXXXXXXXXXXVDTFSELRDLKYKTEKDMKETCFICSRAGHDFDQSSSSFEHHVVYEHNMWAYLFYFLHLKEIKINDYFHLDLYVANMLKRENYDFFPINCALSLTAEQEKYS-RIDEISRNVKIIVSNRQNEEREKLR 7964
            + + MS+ G +   Y + FHL N+++NNQ+L+GVI +VT+NG  L+WV IL VI+ YI+++ +F F+R+ F  ++  Y  TL++  V+++R+G++G ++ + T+P        +  F  F+++ +F L FFI IT  GLN+I GI+VDTFSELRDLK+  E DM++TCFICSR  HDF+   + F  H   EHNMWAY+F+F+HL + K NDY  LDL+VA  L+RE Y+FFP+NCALSLT E++    +ID +   V  ++  ++ EE +++R
Sbjct: 2367 IFVGMSVAGTFFHGYFFAFHLLNIVNNNQILQGVIKAVTQNGVSLLWVGILGVIIFYIYALISFAFMRALFLPKDEEYCGTLLECSVTVIRYGLIGAIFDRLTLPES------ENNFIAFAVVAVFHLSFFILITTIGLNVILGIVVDTFSELRDLKWTAESDMRDTCFICSRGSHDFEHHGNGFLKHAREEHNMWAYIFFFIHLDDTKSNDYTALDLHVAQALQREQYEFFPMNCALSLTGEEDGTDEKIDAVLEKVTELLRRQREEESKRMR 2634          

HSP 3 Score: 26.1794 bits (56), Expect = 2.744e-49
Identity = 22/89 (24.72%), Postives = 40/89 (44.94%), Query Frame = 1
Query: 6919 IFREVVMGLGVSHAVIAFLILITYLITDR---PTLRTIRSYASRIKQRMVSFYKKEDEN------DSEKMVDGTNQLVSLFSFMRFLYC 7158
            I+  ++  +G +H + +  +LI+Y +++    P+L  I +   R+  R     K E+E+      D EK    +   V  FS   F Y 
Sbjct: 2283 IYDLLLYAMGGTHNLFSLFVLISYFLSNHPKCPSLSAIPNLCRRLCGR-----KDEEEDEIAHEVDCEKAKRQSKLDVKFFSLATFYYV 2366          
BLAST of Inositol 1,4,5-trisphosphate receptor type 3 vs. TrEMBL
Match: A0A1S3H6U8 (inositol 1,4,5-trisphosphate receptor type 3 isoform X12 OS=Lingula unguis OX=7574 GN=LOC106152615 PE=4 SV=1)

HSP 1 Score: 1125.54 bits (2910), Expect = 0.000e+0
Identity = 745/2337 (31.88%), Postives = 1234/2337 (52.80%), Query Frame = 2
Query:  164 MNDYLSYGDRICLYCEETNGFINSNNSSSHYNELRIFSKQDKFNPENVSDIQEIIFEVVIQNRXXXXXXXXXXXXDINNKSENLELKIQAEQAKATVISEENDNALENRRNLGKTVHYGDVIQLRHVYTRKYIHVNIAKTSSKDQNSMILNLQSHNLKSAQFKIVPRYKVKYEGEPVQFMDLVTFESLKAPSHYFHASDLYQIDNFFHGAALNLATEQSGFTLIK--SASDTHIMEEDNFLRGGDYIQIIHKEIDGYIESEGIQGGMKKADIYLRIRKSDKFQTLTNSRLSSSANTFWQVEIEKVRLSTEIGQWSSNFRFRHATNRLYLSVKKDLSVSMTKNATNPNTVFRLYP------QNIDKLI-----IPYGRYFRMEHVLTGTWIHANKEQVYVKPNQSKYDDAAE--KCLGNLKYETNELRELFCVHQRLYDDAFVVFKVPTEIVESFNLLSGYFPLIKNLIVDRKKAVPFTASQSYRYKLALEEIRDSLYLDGKPHSLRQKHLRNLQIVDLLVELVLLPFHSKIDAAFTEKIYRASFEILHNYMKGSSIKNSLYFAKYINLFEPKMLENNDLGHKIIEMIAELLRNNQKVLECISFQEIFPFIDNLRINQNFRYLEYLETFCVCNGEPMTQNQIKIAVKWLSEDQ--------------RGVFLTDRGQNLNLESNVIYIKTKLDSNWMKLHEFLDITAQIDQENNPLYHQDNKDYFLKQMDLLLALCYGRNQYCTNLIINKLNYISWEQCFAAINSPMIPPYMKTKYFEIIQTMFIDIGRNYAVIESPKFNFIFNQIQG-------DSSVAVECMFPTPSESVTIKIFKDLSEWIYNFLESTPRMISSNKDFNYLIRIVFITINKLIQYGYYDSPSLDRI-CKSLLKLLNGRNDLPFEYDSKKESLKIRKKLVTKYKNISRYEDSEETRAIVAAKLSGLEILDSILIYERVSVVAKLISRFKKCVQPDLKVQKKRLTGHTHLEACLSNGFDVAQQYKQSNRATKKMVSEIDNLFTTARFLDSEPWTNILIDLAHYQNEMMTQKSLLILHKLYSIKESSFQDTYATFISKTKQSQDLQELMCEYIPALRLHTKSLIGPPDLEKIAAMITEMINVCKIPKSDSF-NPISQRIIVGYGILD-----IAMETIAQIYRSFDRSKMMYGASEVISLITNLLRHLAISNPSFQEXXXXXXXXXXXXYEHSPPAELADLLRCGLFHNNRTFCGTLKSFQINKIVLMVADTARKNPLVGAAFIHLLESIVAVNNGEVPLKRNQLMVMKFVMKSFNQLVYILDSKSMSRVDLLTIHSASNDAFYFTKVIDLFIACCQGENQYVQSLCQTIMPLDELFDLLTHNDISIIYKRGLLKYFSKVYLSRTNISNQEGIIKNFIESKYCGEILDSIERTTLLTQIILDKTEHFNLLPILKKEFILKPPTEFQVSE----NIQMHLHYIIFGSSI--FMASLCSAFSIMEISPAPELMKVIKSINH---ITMDIFSQMWKFQLHPSVFSVITESVLQIIS----------YTDTSDLEAKTMALQHCKPQIMDF------------DPRKEIDNLYT----EEIELNLKLQTFIFNCSQLIAGQNTVKAQIKANLRKQYVNLLDQNALPLNLEYQNHLKCFINNSYQKGEIRRYKLVDILIRQLEISGSVERNGKRHTKLDRNSFSKTIKRLDQDALDLRSLQILRGLIYNEECLLPDNWELKIFNSSVQDILKCIKNVQNCLNKLNLSSRTQIHMVNSCDLVKREAITLQSAMLMNANKNVQESLLRYFKGAQEEVFFSAIKYQLQNAFTDLKDQKLMLSQKKSFGDIEKYTCHESDLRIDNLAHILYQQLAEYEIRYEDQNRSLAINRYAYTTTKESFTTRHMRQIYTPAKMKS----EINSSSPLICCPRNSSKSNYDMR------STDKSDSLFKNNLQDEYELKSVVTKESNSSTDKTIENSAWIKGETLDLMRNDPHQNVKLILQLLSRMCVGQYQGLQNYLRIQPDNRSSVDVISLIVQFLGNIYANVRQSTIDLSIQAFDTIKETIMGNQENRSVVYRAKVVDYANFILRNDEISETCDPNNVLQMFLVIGRVIMALIEENGREETELAKEIQITLDIKAVFKIMTRCL--------------------------------DMMEDTKRKLIKNKIYDVGFTYFLILARLEDL---CNGKLLKHFQISDQQMKAXXXXXXGSASVEILKGDQLQRIHFRLKHKEVLRESVKEKVKWEVDRTTPSNKIRSFISWSKLILPDMNFQRKIIQNPLLLFVTKQWNAMNYFLTLLSLVINIL 6805
            M ++L  GD I L+CEET G++ S  +SS +N L I+  QD+  P  + +   I F V IQNRYKL KKY K     +   ENLELK    QAK +  +E  DN  E +R  GK V YG++IQL+HV+T KY+H++  +TS +D+N+M+++L  +N K AQF+I+PRYKVK EGE VQ +D + +ES K+  HYFH+S  + I+    G+ LNL   Q+GFT+++    SD    E +  +RG  +I++ HKE++ Y+ +EG+ G   + +++LRIR+ D+    T S   +SA T+WQVE E   L+  + +W    R RH T R +L +  D  V +T    +P +VFR +P      Q++D        I +  Y R+EHVLTG W+HA K++    P Q + D   E  + +  L+++  E+R++     R Y D F + +V  E + S N ++G  P +  LI  R++     A ++++   AL+E++  + ++G+ +   QK +RN +IVDLLV+L+  P     D+ +   +++ +++IL+ YM G+S KN+LYFAKYI  F+ ++    D+G  + +M+ EL+R+N+++++ I+ ++I  F+D LR  +N+R+L+ L   CVC+G+ + +NQ  I   WL  D+                V+L +RGQ ++ E NV+YI T     W+ LH+F +        ++P Y ++   Y  +Q+DLL  LC GRNQ+   +I   L+ ++WE  F  + S ++PP ++ KY  +I  +F+D+G +++V++     F++  I          S VA   +F          + +D   WI  F+ES P M SS    N LI  V   +  L+++G Y S    RI  K L+ +L+GRND PF  +++ ++ K  KKLV +Y+   R+E S ET+A+V AK  GL +L+ +  ++  + +   +S+FK     +     K+    + L   + + +D     K++ R  KK + E+  +F ++ + D E  TNI +DL++Y+ E M  +SL IL+K YS K   F+    T +  T++S  +   +   +P +R   K        E ++ +  + +    +    +  +P++Q+I++ +G+LD     ++ E   QI       ++++G +       NLLR LA  N   Q  + + LD+L+++     P+ LA  LR  +F  N+  C  ++  QI KIV +  +   + P     F+ LL SIV V   E+PLKRNQ +VMK++M+++++  Y+ D     R+ +LT  + ++   Y   ++DL   C +GEN+Y++SLCQTIMP++E+ D+L ++ I    K   L+Y   VY+       + G   +    ++    + ++ R     +  + + E      +   E +  PP +  V+E    +   H     F  ++  F+ +  + F   +    P+ ++ +  + H   +  D    +     H  V      SVLQ  S           T+   L+ K + L     ++M+             DP +E  + YT     E ELN K + F  NCS +  G NTV AQ+K   +++Y  +     LPL  E+Q H++CF+ ++ +K   +RY+ V  L++QL +S               N+ +      + D LD++SLQILR +I+NEE  L ++WE    +  VQ  LK I  VQN LN  +       H+    + + RE++   S ML NAN+NVQ+++L YF   ++E FF AI+ +LQ +   +K+++ + +Q            HE+ ++             E   + +    +L + R A    +    +R   ++   A+  S    + +  S L      SSK N   R      S ++   L   +  ++ EL  V+ + S++ +    E+      + LD +       + L+L+LL+ MC GQ Q +Q+YLR QPDN  S++V++   QF+  +Y+N+  STIDL IQ F T+ E   GNQ NR V+   KVVDY NFILR  +  E       L++  VI  ++++LIEENG E  ++A+E++ T+D +AV++ M  C                                 ++ME  K+  +K+K Y+VGF YFL++AR  D+    N K      I+  QM A+ ++KK S S+E++K   LQ++HFR+K+K VLRE VKEK+KW+VDR++PSNKIR  ++WSK IL D+ +QRK+++NP+ +F TK W   NY + LLS+ IN+L
Sbjct:    1 MGEFLCIGDYISLFCEETEGYVYSYQTSSSHNGLYIYQGQDRKKPGKIPNPHAITFRVCIQNRYKLNKKYRKLLAASSKDPENLELKALVAQAKTSANAENQDNISEQKRQHGKRVRYGEIIQLKHVFTDKYVHISTTQTSHRDKNNMLISLHQYNGKHAQFRILPRYKVKSEGEYVQILDQIVYESFKSQGHYFHSSVPWNIEKDMVGSELNLGVAQTGFTVVRYYRPSD----ENEANVRGSSFIRLFHKELEAYLVAEGLFGEPVQEEVHLRIREIDQLNPRTLSP-PNSAITYWQVEPEDTILNGGVVRWEQQVRLRHVTTRRFLCLDADFEVCLTAEENDPRSVFRFHPVLSLREQDLDPDTPEQNEIDFESYCRIEHVLTGNWLHALKDE----PYQRRRDMGRENDRSMQALRWDGGEVRKISSTENRRYVDVFTIHEVEWEQIYSANFVAGMVPFLSKLIESREECDYLNAMKTHQITTALQELKQFMIINGETYKDHQKLMRNFRIVDLLVQLLQSPLQDAPDSNYLLSVFKEAYDILYTYMTGNSRKNALYFAKYIEFFQTQLSLKGDIGLNVAQMLVELIRDNRQIVDRITHEQIDIFVDLLRQRKNYRFLDLLNVLCVCDGKTILENQSYITETWLRHDKVSFDAKTCHIHLTGADVYLIERGQYIHKEHNVVYISTDAGHTWVPLHQFANA-------DSPYYSEEEYLYLDRQLDLLGKLCKGRNQFSIRVITKDLDILTWENTFVCLRSELLPPSLRAKYCSLIIDLFVDVGASHSVLDQHTLVFVYEDIDNPRPLYSTKSQVATNVLFLAQELGTVFPVMRD---WIQEFVESNPEMYSSQVGQNKLIEQVMRLLCYLVRFGCYCSADEIRILLKPLMIMLDGRNDRPFPKNAEIQNSKEVKKLVKQYRETDRFEKSAETKALVDAKYQGLSVLELLFTFQSNTRLESFVSKFKTA---ETTANAKKKKHRSVLSPLVDDSYDAFNTSKKNLRKQKKFLHELRAMFESSSYFDVEYITNISLDLSNYKYEKMLTQSLNILNKYYSSKTDMFKIAIPTLVLTTQESCKIHIDIMRQLPLVRHLAKCSYNMEQAEAMSVVFDQFVLFTHLRDEPTLRHPMNQKILINHGVLDLIFAILSQEVDVQITEQAAPMELVFGKA------LNLLRFLAQGNEDVQAKMNDRLDSLMNI--KLVPSHLAIALR-EVFAGNQNNCLKIQPKQILKIVHLAGENQDRAP----EFLDLLGSIVKVELLELPLKRNQGLVMKYLMQNYHKAAYLFDQSQEDRLRILTSKTGNSHQRYLISLVDLLAKCAEGENRYIESLCQTIMPIEEIMDVLNNHFIDNNLKSPYLRYLMWVYMKTAGTMIESG-AGDLPHDRHVWIYIQALAREAESLKTYISENE------VKTVEVMRAPPPKGAVAEMDDSDGAAHATLFYFFDAVLPFLQTFFTKFYSPDKELYPDELEYVDQLAHSLVLWCDRVGAVLCNATHLKVLIGCVPSVLQSSSIPKNLSTESALTNYPSLKPKQVQLWKNTYKVMEGFIEQYGNGRCLRDPTRETIDTYTIYYQNEDELNKKFRAFSVNCSLVYGGHNTVTAQLKHKSKREYTEIGGDEDLPLGEEFQAHVRCFVKHN-EKNIAKRYQNVSKLVQQLAVSA--------------NAVNPKDGTYENDELDIKSLQILRAVIHNEERKLREDWEENTQDKKVQKQLKVILEVQNTLNSYSAVEEVLPHLGRPSNAIVRESLAFLSIMLFNANRNVQKAMLEYFMSTKKESFFFAIRCRLQLSAIAIKERRALATQ------------HEARVK-------------ESMTQAKSLQTNLTVGRKAMKDIQAIERSRRQSRLMKGARANSLRALQRDRQSGLTSISPASSKCNSLQRFKLPNGSLNEETPLVFGSNHNDIELNEVMVEGSDNLSVDVEED------DVLDGLEFKDEGYIVLVLRLLAAMCDGQNQSIQDYLRDQPDNIKSINVVADTAQFVNVVYSNITASTIDLVIQLFSTLNEFTAGNQANRVVLLDNKVVDYINFILRAGKY-EGISMEMQLELREVIANLLVSLIEENGPEPIKVAREVKDTVDKEAVYRCMVDCYSIHQPPTYKAKISTNMGDNMKNLSQMGGGLLREIMEKNKKNDLKDKAYEVGFLYFLLMARFYDIDPVLNEK--AGLVITPDQMAAYNYYKKNSMSIELMKDGNLQKVHFRVKNKNVLREEVKEKLKWDVDRSSPSNKIRDLMAWSKDILKDIYYQRKMLRNPIAVFFTKFWLLWNYLVILLSVAINVL 2246          

HSP 2 Score: 203.371 bits (516), Expect = 2.590e-49
Identity = 123/274 (44.89%), Postives = 188/274 (68.61%), Query Frame = 3
Query: 7152 LLLSMSIGGIWI-PYLYVFHLFNVIHNNQLLKGVIASVTKNGRXXXXXXXXXXXXXXXFSIFAFCFLRSTFSSENYLYADTLVQTFVSLVRFGIVGDLY-QYTIPHKYYMKTVDTAFTEFSXXXXXXXXXXXXXXXXXXXXXXXXXVDTFSELRDLKYKTEKDMKETCFICSRAGHDFDQSSSSFEHHVVYEHNMWAYLFYFLHLKEIKINDYFHLDLYVANMLKRENYDFFPINCALSLTAEQEKYS-RIDEISRNVKIIVSNRQNEEREKLR 7964
            + + MS+ G +   Y + FHL N+++NNQ+L+GVI +VT+NG  L+WV IL VI+ YI+++ +F F+R+ F  ++  Y  TL++  V+++R+G++G ++ + T+P        +  F  F+++ +F L FFI IT  GLN+I GI+VDTFSELRDLK+  E DM++TCFICSR  HDF+   + F  H   EHNMWAY+F+F+HL + K NDY  LDL+VA  L+RE Y+FFP+NCALSLT E++    +ID +   V  ++  ++ EE +++R
Sbjct: 2367 IFVGMSVAGTFFHGYFFAFHLLNIVNNNQILQGVIKAVTQNGVSLLWVGILGVIIFYIYALISFAFMRALFLPKDEEYCGTLLECSVTVIRYGLIGAIFDRLTLPES------ENNFIAFAVVAVFHLSFFILITTIGLNVILGIVVDTFSELRDLKWTAESDMRDTCFICSRGSHDFEHHGNGFLKHAREEHNMWAYIFFFIHLDDTKSNDYTALDLHVAQALQREQYEFFPMNCALSLTGEEDGTDEKIDAVLEKVTELLRRQREEESKRMR 2634          

HSP 3 Score: 26.1794 bits (56), Expect = 2.590e-49
Identity = 22/89 (24.72%), Postives = 40/89 (44.94%), Query Frame = 1
Query: 6919 IFREVVMGLGVSHAVIAFLILITYLITDR---PTLRTIRSYASRIKQRMVSFYKKEDEN------DSEKMVDGTNQLVSLFSFMRFLYC 7158
            I+  ++  +G +H + +  +LI+Y +++    P+L  I +   R+  R     K E+E+      D EK    +   V  FS   F Y 
Sbjct: 2283 IYDLLLYAMGGTHNLFSLFVLISYFLSNHPKCPSLSAIPNLCRRLCGR-----KDEEEDEIAHEVDCEKAKRQSKLDVKFFSLATFYYV 2366          
BLAST of Inositol 1,4,5-trisphosphate receptor type 3 vs. Ensembl Cavefish
Match: itpr1a (inositol 1,4,5-trisphosphate receptor, type 1a [Source:ZFIN;Acc:ZDB-GENE-070604-3])

HSP 1 Score: 127.102 bits (318), Expect = 2.532e-28
Identity = 217/951 (22.82%), Postives = 398/951 (41.85%), Query Frame = 2
Query:  164 MNDYLSYGDRICLYCE-ETNGFINSNNSSSHYNELRIFSKQDKFNPENVSD-IQEIIFEVVIQNRXXXXXXXXXXXXDINNKSENLELKIQAEQAKATVISEENDNALENRRNLGKTVHYGDVIQLRHVYTRKYIHVNIAKTSSKDQNSMILNLQSHNLKSAQFKIVPRYKVKYEGEPVQFMDLVTFESLKAPSHYFHASDLYQIDNFFHGA----ALNLATEQSGFTLIKSASDTHIMEEDNFLRGGDYIQIIHKEIDGYIESEGIQGGMKKADIYLRIRKSDKFQTLTNSRLSSSANTFWQVE-IEKVRLSTEIGQWSSNFRFRHATNRLYLSV-------------KKDLSVSM--------------------TKNATNPNTVFRLYPQNI--DKLIIPYGRYFRMEHVLTGTWIHANKEQVYVKPNQSKYDDAAEKCLGNLKYETNELRELFCVHQRLYDDAFVVFKVPTEIVESFNLLSGYFPLIKNLIVDRKKAVPFTASQSYRYKLA--LEEI-----------RDSLYLD-GKPHSLRQKHLRNLQIVDLLVELVLLPFHSKIDA-------------AFTEKIYRASFEILHNYMKGSSIKNSLYFAKYINLFEPKMLENNDLGHKII--EMIAELLRNNQKVLE-CISFQEIFPFIDNLRINQNFRYLEYLETFCVCNGE--PMTQNQIKIAVKWLSEDQRGVFLTDRGQNLNLESNVIYIKTKLDSNWMKLHEFLDITAQIDQENNPLYHQDNKD----------YFLKQMDLLLALCYGRNQYCTNLIINKLNYISWEQCFAAINSPMIPPYMKTKYFEIIQTMFIDIGRNYAVIESP-KFNFIFNQIQGDSSVAVECMFPTPSESVTIKIFKDLSEWIYNFL-----ESTPRMISSNKDFNYLIRIVFITINKLIQYGYYDSPSLDRICKSLLKLLN 2746
            M+ +L  GD   LY E  T+GFI    S+    + R   + D  +  N     ++ +F +   NRY   K++ K  K     + +  L  +   A      E+  N  EN++ LG  + YG+VIQL H+ + KY+ VN    +  ++N+M + L +   + + F I P YK++  G+ V   D V    + A     HAS    +DN   G     ++N +T       +K + +  ++     L+GGD +++ H E + ++  +  +   KK  ++LR   +   Q+ T+   ++S+   W+VE ++        G W+S FRF+H     YL+              +  +SV +                      +  + +++F L P  +     ++P   Y R+ H+ T TW+H+    +          D  E+    L+  T+ L+E          +AF +  V    V   +  +    ++ ++    +K    T +Q+ R  +   LE++           +D L +   KP+  RQK +R   I+  + +L+  PF    D              A    I R  + +L +  +    KN  Y AK     + +      +G+ ++  + I  LL NN+K+LE  I+  EI  F+  +R N+  R+L+YL   CV   +  P+TQ  I  AV    +   G  L +   +    +N   +  + D   + L  + D + ++  ++     QD KD          Y+  Q++L   +C  R     N I  +L+     +C +  +   +P  ++  +  ++  M +D  R+     +P K+  ++++I    S+       T  + V  K F    E++ N+L     +S P    S+K+ N L   V      LI +G+Y+   L R+ K LL +L+
Sbjct:    5 MSSFLHIGDICSLYAEGSTSGFI----STLGLVDDRCVVQPDAGDLNNPPKKFRDCLFRLCPMNRYSAQKQFWKAAKPGGTSTTDTVLLNKLHHAADL---EKKQNESENKKLLGTVIQYGNVIQLLHLKSNKYLTVNKRLPALLEKNAMRVTLDAAGNEGSWFYIQPFYKLRSIGDSVVIGDKVVLNPVNA-GQPLHASGHQLVDN--PGCNEVNSVNCSTSWKIVLFMKWSDNQEVV-----LKGGDVVRLFHAEQEKFLTCDDHR---KKQYVFLR---TTGRQSATS---ATSSKALWEVEVVQHDPCRGGAGYWNSLFRFKHLATGHYLAAEVNPDYEEECLESRSSVSVCLLYTQLWKKLRDHFIMYTLVSVPDGNDISSIFELDPTTLRGGDSLVPRNSYVRLRHLCTNTWVHSTNHPI----------DKEEEKPVMLRIGTSPLKE--------DKEAFAIVPVSPAEVRDLDFANDASKVLASIAGKLEKG---TITQNERRAVTKLLEDLVYFVVDIPNSAQDVLEITVNKPNRERQKLMREQNILKQIFKLLQAPFTDSGDGPMLRLEELADQRHAPFRHICRLCYRVLRHSQQDYR-KNQEYIAKQFRFMQKQ------IGYDVLAEDTITALLHNNRKLLEKHITAAEIDTFVSLVRKNREPRFLDYLSDLCVSMNKSIPVTQELICNAVL---DPANGDILIETKYDKICATNHCRLTDREDEEEVWLF-WKDSSGEVKSKSIRELAQDAKDGHTEDQEVISYYRYQLNLFARMCLDRQYLAINKISAQLDVDLILRCMSDED---LPFDLRASFCRMMLHMHVD--RDPQEQVTPVKYARLWSEIPSQISIDDYDNDGTSRDEVKEK-FSQTMEFVENYLRDVVCQSFP---FSDKEKNKLTFEVVNLARNLIYFGFYNFSDLLRLTKILLAILD 890          

HSP 2 Score: 82.0333 bits (201), Expect = 1.047e-14
Identity = 45/129 (34.88%), Postives = 70/129 (54.26%), Query Frame = 3
Query: 7584 VDTFSELRDLKYKTEKDMKETCFICSRAGHDFDQSSSSFEHHVVYEHNMWAYLFYFLHLKEIKINDYFHLDLYVANMLKRENYDFFPINCALSLT-----AEQEKYSRIDEISRNVKIIVSNRQNEERE 7955
            +DTF++LR  K + E+ +K TCFIC      FD  + +FE H+  EHN+W YL++ + ++     +Y   + YVA M+K  N D+FP   A+SL       EQ +   + E   +   +VSN  N+  E
Sbjct: 2471 IDTFADLRSEKQRKEEVLKTTCFICGLERDKFDNKTVTFEEHIKEEHNLWHYLYFIVLVRVKDSTEYTGPESYVAQMIKEHNLDWFPRMRAMSLVSSDGEGEQNELRCLQEKLESTMRLVSNLTNQLTE 2599          
BLAST of Inositol 1,4,5-trisphosphate receptor type 3 vs. Ensembl Cavefish
Match: itpr2 (inositol 1,4,5-trisphosphate receptor, type 2 [Source:ZFIN;Acc:ZDB-GENE-050419-192])

HSP 1 Score: 126.716 bits (317), Expect = 3.309e-28
Identity = 215/943 (22.80%), Postives = 399/943 (42.31%), Query Frame = 2
Query:  173 YLSYGDRICLYCEET-NGFINSNNSSSHYNELRIFSKQDKFNPENVSDIQEIIFEVVIQNRXXXXXXXXXXXXDINNKSENLELKIQAEQAKATVISEENDNALENRRNLGKTVHYGDVIQLRHVYTRKYIHVNIAKTSSKDQNSMILNLQSHNLKSAQFKIVPRYKVKYEGEPVQFMDLVTFESLKAPSHYFHASDLYQIDNFFHGA----ALNLATEQSGFTLIKSASDTHIMEEDNFLRGGDYIQIIHKEIDGYIESEGIQGGMKKADIYLRIRKSDKFQTLTNSRLSS-SANTFWQVEI---EKVRLSTEIGQWSSNFRFRHATNRLYLSVKKDLSVSMTK-------------NATNPNTVFRLYPQNIDKL-----IIPYGRYFRMEHVLTGTWIHANKEQVYVKPNQSKYDDAAEKCLGNLKYETNELRELFCVHQRLYDDAFVVFKVPTEIVESFNLLSGYFPLIKNLIVDRKKAVPFTASQSYRYKLALEEI-----------RDSL-YLDGKPHSLRQKHLRNLQIVDLLVELVLLPFHSKIDAAFTE---------KIYRASFEILHNYMKGSS---IKNSLYFAKYINLFEPKMLENNDLGHKII--EMIAELLRNNQKVLE-CISFQEIFPFIDNLRINQNFRYLEYLETFCVCNGE--PMTQNQIKIAVKWLSEDQRGVFLTDRGQNLNLESNVI-YIKTKLDSNWMKLHEFLDITA----QIDQENNP----LYH--QDNKD----------YFLKQMDLLLALCYGR-----NQYCTNLIINKLNYISWEQCFAAINSPMIPPYMKTKYFEIIQTMFIDIGRNYAVIESPKFNFIFNQIQGDSSVAVECMFPTPSESVTIKIFKDLSEWIYNFLE---STPRMISSNKDFNYLIRIVFITINKLIQYGYYDSPSLDRICKSLLKLLN 2746
            +L  GD + LY E T NGFI++         ++     D  NP      ++ +F+V   NRY   K++ K  +     +   +L  + + A      E+  N  EN++ LG+ V Y  VIQL H+ + KY+ VN    +  ++N+M ++L     + + F I P +K++ EG+ V   D V    + A     HAS++  +DN   G     A+N  T     TL    SD     +D+ L+GGD +++ H E + ++  +  +    +  I+LR        TL  S  S+ S+   W+VE+   +  R     GQW+S FRF+H     YL+ + +     +K             +  + N +  L+  +   L     ++P   Y R+ ++ T TW+ +    +          D  E+    LK  T   +E          +AF +  VP   V   +  +    +++  +   +K       + +  KL LE++           +D L  +   P+  RQK +R   I+  +  ++  PF  + D    +           ++   ++ +  ++ S     KN  Y AK  ++ + +      +G++I+  + I  LL NN+K+LE  I+ +EI  F+  LR N+  R+L+YL   CV N    P+TQ  I    K++        L     ++ +++ +I + +  +DS+ M  HE  D        ID    P    + H  QD+K           Y+  Q++L   +C  R     NQ  T L ++ +    ++ C        +P  ++  +  ++  M +D     AV+   ++  ++N+I    SV  +      S +   + F    +++  +L+   S P      +     + +V +  N L+ +G+Y    L  + ++LL +L+
Sbjct:    8 FLHIGDIVSLYAEGTVNGFISTLGLVDDRCVVQP-EAGDLANPP--KKFRDCLFKVCPMNRYSAQKQFWKAKQGKQGGNTEGDLFKKLQHAAEL---EQKQNETENKKLLGEVVKYSQVIQLLHIKSNKYLTVNKRLPALLEKNAMRVSLDPSGNEGSWFYIQPFWKLRSEGDNVVVGDKVVLMPVNA-GQPLHASNIELLDN--PGCNEVNAVNCNTSWK-VTLFMKFSDY----KDDILKGGDVVRLFHAEQEKFLTCDDYK---DQQHIFLRT-------TLRQSATSATSSKALWEVEVVHYDPCRGGA--GQWNSLFRFKHLATGKYLAAETESDAVYSKKKRPVEKITYILVSVPHGNDIASLFELDATTLQRADCLVPRNSYVRLRNLCTNTWVTSTNNSI----------DHEEERPVMLKIGTCPTKE--------DKEAFAIVSVPLSEVRDLDFANDANKVLEAFVRKLEKNTFAQNDRRFVIKL-LEDLVFFVCEVPNNGQDVLSVVISNPNRERQKLMREQNILAQIFGILKAPFADREDGPILKLEDLGDQRYAPFKYMLQLCYRILRHSQQDYRKNQEYIAKKFSIMQSQ------IGYEILAEDTITALLHNNRKLLEKHITAREIETFVKLLRRNREPRFLDYLSDLCVSNKTAIPVTQELI---CKFM--------LNPTNADILIQTKLIPHTENSMDSSLM--HEEGDEEEVWLYWIDHNKEPHGKSIRHLAQDSKGNHKLDIDIITYYRCQLNLFAKMCLDRQYLAINQISTQLPVDLILRCMFDDC--------LPYNLRASFCRLMLHMHVDRDPQEAVVPV-RYARLWNEIPSKISVKEDT-----SRADMKRKFAPTMDFVDEYLKDVLSQPFPFGDEEKNELTLEVVNLARN-LVYFGFYSFSELLCLTRTLLAILD 871          

HSP 2 Score: 92.4337 bits (228), Expect = 7.813e-18
Identity = 88/293 (30.03%), Postives = 148/293 (50.51%), Query Frame = 3
Query: 7134 FLYEISLLLSMSIGGIWIPYLYVFHLFNVIHNNQLLKGVIASVTKNGRXXXXXXXXXXXXXXXFSIFAFCFLRSTF--------------------SSENYLYADTLVQTFVSLVRFGI-----VGDLYQYTIPHKYYMKTVDTAFTEFSXXXXXXXXXXXXXXXXXXXXXXXXXVDTFSELRDLKYKTEKDMKETCFICSRAGHDFDQSSSSFEHHVVYEHNMWAYLFYFLHLKEIKINDYFHLDLYVANMLKRENYDFFPINCALSL--TAEQEKYSRIDEISRNVKIIVS 7931
            FL  +  ++   +G     + Y   LF+++   + L  V+ SVTKNGR +    +L +I++Y+FSI  F FL+S F                      E     +TL+   V+++  G+     + D+ +   P K      D     F+  +++ L FF  + I  LN+IFG+I+DTF++LR  K + E+ +K TCFIC      FD  + SFE H+  EHNMW YL++ + ++     +Y   + YVA M+K +N D+FP   A+SL  +A + + + +  +   + I V+
Sbjct: 2222 FLLHVFYVIVCMLGLFVHEFFYSILLFDLVRREETLLNVMRSVTKNGRSIFLTAVLAIILVYLFSIVGFLFLQSDFLMEVDRHPALDLTCKVEKSDEPEMERVCETLLMCIVTVLNHGLRNGGGIADILRK--PSK------DEPM--FAARVVYDLLFFFIVIIIVLNLIFGVIIDTFADLRSEKQRKEEILKTTCFICGLERDKFDNKTVSFEEHIKVEHNMWHYLYFLVLVRVKDPTEYTGPESYVAQMIKEKNLDWFPRMQAMSLVTSAGESEQNEMRSLQEKLDITVT 2504          
BLAST of Inositol 1,4,5-trisphosphate receptor type 3 vs. Ensembl Cavefish
Match: itpr1b (inositol 1,4,5-trisphosphate receptor, type 1b [Source:ZFIN;Acc:ZDB-GENE-070604-2])

HSP 1 Score: 124.405 bits (311), Expect = 1.513e-27
Identity = 168/702 (23.93%), Postives = 295/702 (42.02%), Query Frame = 2
Query:  164 MNDYLSYGDRICLYCE-ETNGFINSNNSSSHYNELRIFSKQDKFNPENV-SDIQEIIFEVVIQNRXXXXXXXXXXXXDINNKSENLELKIQAEQAKATVISEENDNALENRRNLGKTVHYGDVIQLRHVYTRKYIHVNIAKTSSKDQNSMILNLQSHNLKSAQFKIVPRYKVKYEGEPVQFMDLVTFESLKAPSHYFHASDLYQIDNFFHGA----ALNLATEQSGFTLIKSASDTHIMEEDNFLRGGDYIQIIHKEIDGYIESEGIQGGMKKADIYLRIRKSDKFQTLTNSRLSSSANTFWQVE-IEKVRLSTEIGQWSSNFRFRHATNRLYLSV---------------------------------KKDLSVSMTKNATNPNTVFRLYPQNI--DKLIIPYGRYFRMEHVLTGTWIHANKEQVYVKPNQSKYDDAAEKCLGNLKYETNELRELFCVHQRLYDDAFVVFKVPTEIVESFNLLSGYFPLIKNLIVDRKKAVPFTASQSYRYKLALEEI-----------RDSL-YLDGKPHSLRQKHLRNLQIVDLLVELVLLPFHSKIDA-------------AFTEKIYRASFEILHNYMKGSSIKNSLYFAKYINLFEPKMLENNDLGHKII--EMIAELLRNNQKVLE-CISFQEIFPFIDNLRINQNFRYLEYLETFCVCNGE--PMTQNQIKIAV 2053
            M+ +L  GD   LY E  TNGFI    S+    + R   + D  +  N     ++ +F++   NRY   K++ K  K   N + +  L  +   A      E+  N  ENR+ LG  + YG+VIQL H+ + KY+ VN    +  ++N+M + L S   + + F I P YK++  G+ V   D V    + A     HAS    +DN   G     ++N  T       +K + +  ++     L+GGD +++ H E + ++  +  +   KK  ++LR   +   Q+ T+   ++S+   W+VE ++        G W+S FRF+H     YL+                                  K   ++    +  + +++F L P  +     ++P   Y R+ H+ T TW+H+    +          D  E+    L+  T+ ++E          +AF +  VP   V   +  +    ++ ++    +K       + +  KL LE++           +D L  +  KP+  RQK +R   I+  + +L+  PF    D              A    I R  + +L +  +    KN  Y AK     + +      +G+ ++  + I  LL NN+K+LE  I+  EI  F+  +R N+  R+L+YL   CV   +  P+TQ  I  AV
Sbjct:    5 MSSFLHIGDICSLYAEGSTNGFI----STLGLVDDRCVVQPDTGDLNNPPKKFRDCLFKLCPMNRYSAQKQFWKAAKPGGNSTTDTVLLNKLHHAADL---EKKQNESENRKLLGTVIQYGNVIQLLHLKSNKYLTVNKRLPALLEKNAMRVTLDSAGNEGSWFYIQPFYKLRSIGDSVVIGDKVVLNPVNA-GQPLHASTHQLVDN--PGCNEVNSVNCNTSWKIVLFMKWSDNKEVI-----LKGGDVVRLFHAEQEKFLTCDDHR---KKQYVFLR---TTGRQSATS---ATSSKALWEVEVVQHDPCRGGAGYWNSLFRFKHLATGHYLAAEVNPDYEEESHESRSSLDSEHEALRARLRTPNEKVMYTLVSVPDGNDISSIFELDPTTLRGGDSLVPRNSYVRLRHLCTNTWVHSTNNPI----------DKEEEKPVMLRIGTSAIKE--------DKEAFAIVPVPPAEVRDLDFANDASKVLASIAGKLEKGTITQNERRFVTKL-LEDLVFFVVDIPNSGQDVLEIMVNKPNRERQKLMREQNILKQIFKLLQAPFTDSGDGPMLRLEELGDQRHAPFRHICRLCYRVLRHSQQDYR-KNQEYIAKQFRFMQKQ------IGYDVLAEDTITALLHNNRKLLEKHITAAEIDTFVSLVRKNREPRFLDYLSDLCVSMNKSIPVTQELICNAV 656          

HSP 2 Score: 86.6557 bits (213), Expect = 3.786e-16
Identity = 50/147 (34.01%), Postives = 76/147 (51.70%), Query Frame = 3
Query: 7584 VDTFSELRDLKYKTEKDMKETCFICSRAGHDFDQSSSSFEHHVVYEHNMWAYLFYFLHLKEIKINDYFHLDLYVANMLKRENYDFFPINCALSLT-----AEQEKYSRIDEISRNVKIIVSN----------RQNEEREKLRRTNLF 7979
            +DTF++LR  K K E+ +K TCFIC      FD  + +FE H+  EHNMW YLF+ + +K     +Y   + YVA M++  N D+FP   A+SL       EQ +   + E   +   +VSN          +  E+R++ +R  L 
Sbjct: 2546 IDTFADLRSEKQKKEEVLKTTCFICGLERDKFDNKTVTFEEHIKVEHNMWHYLFFIVLIKVKDSTEYTGPESYVAEMIREHNLDWFPRMRAMSLVSSDAEGEQNEIRSLQEKLESTMKLVSNLSGQLTELKEQMTEQRKQKQRIGLL 2692          
BLAST of Inositol 1,4,5-trisphosphate receptor type 3 vs. Ensembl Cavefish
Match: ryr3 (ryanodine receptor 3 [Source:ZFIN;Acc:ZDB-GENE-041001-165])

HSP 1 Score: 80.1073 bits (196), Expect = 4.767e-14
Identity = 69/240 (28.75%), Postives = 119/240 (49.58%), Query Frame = 3
Query: 7161 SMSIGGIWIPYLYVFHLFNVIHNNQLLKGVIASVTKNGRXXXXXXXXXXXXXXXFSIFAFCFLRSTFS-SENYLYADT---------LVQTFVSLVRFGIVGDLYQYTI--PHKYYMKTVDTAFTEFSXXXXXXXXXXXXXXXXXXXXXXXXXVDTFSELRDLKYKTEKDMKETCFICSRAGHDFDQSSSSFEHHVVYEHNMWAYLFYFLHLKEIKINDYFHLDLYVANMLKRENYDFFP 7844
            +MSI G +  + +  HL ++    + L+ +++SVT NG+ L+  + L+ +V+Y++++ AF F R  ++ SE+    D          L   +V +   G +GD  +     P++ Y    D  F  F             + +  L II G+I+D F ELRD + + ++DM+  CFIC      FD +   FE H + EHN+  YLF+ ++L      ++   + YV  M +   +DFFP
Sbjct: 4463 TMSILGHYNNFFFAAHLLDIAMGFKTLRTILSSVTHNGKQLVLTVGLLAVVVYLYTVVAFNFFRKFYNKSEDEDAPDMKCDDMMTCYLFHMYVGVRAGGGIGDEIEDPAGDPYELYRILFDITFFFF-------------VIVILLAIIQGLIIDAFGELRDQQEQVKEDMETKCFICGIGNDYFDTTPHGFETHTLQEHNLANYLFFLMYLINKDETEHTGQESYVWKMYQERCWDFFP 4689          

HSP 2 Score: 53.5286 bits (127), Expect = 4.278e-6
Identity = 121/540 (22.41%), Postives = 205/540 (37.96%), Query Frame = 2
Query:  503 KTVHYGDVIQLRHVYTRKYIHVNIAKTSSKDQNSMILNLQSHNLKSAQFKIVPRYKVKYEGEPVQFMDLVTFESLKAPS--HYFHASDLYQIDNFFHGAALNLATEQSGFTLIKSASDTHIMEEDNFLRGGDYIQIIHKEIDGYIESEGIQGGMKKADIYLRIRKSDKFQTLTNSRLSSSANTFWQVEIEKVRLSTEIGQWSSNFRFRHATNRLYLSVKKDLSVSMTKNATNPNTV----FRLYPQNIDK-----------LIIPYGR--YFRMEHVLTGTWIHANKEQVYVKPNQSKYDDAAEKCLGNLKYETNELRELFCVHQRLYDDAFVVFKVPTEIVESFNLLSGYFPLIKNLIVDRKKAVPFTASQ-SYRYKLALEEIRDSLYLDGKP-----HSLRQKHLRNL-QIVDLLVELVLLPFHSKIDAAFTEKIYRASFEILH-NYMKGSSIKNSLYFAKYINLFEPKMLENNDLGHKIIEMIAELLRNNQKVLECISFQEIFPFIDNL-RINQNFRYLEYLETFCVCNGEPMTQNQ 2038
            +T+ YG  I LRH +                  S ++ ++    ++  + I P  K + EGE V+  D +   S+ +    H   ++   Q+D  F     N+    SG       S+  +     +L GG  I++ H    G+ ES  + G  +  +         +       +  S A + W++E  ++  S    +W   FR RH +   YL   +D  + +     +  T     FR   + +D              I YG    F M HV TG W+       Y  P      DA    LG LK      R  F   +   DD  ++     E   +  ++     L    I     +VP TAS+ S      ++ + D +    +P     H  +Q+ LR+L +  DL  E V L F  ++   + +      + ILH   +   +  N   F++ ++    K LE  +    I+E +  +L  + + L  I    I   I  L +  +N + L+ L + CVCNG  +  NQ
Sbjct:   89 RTLLYGHAILLRHSF------------------SGMVRMR----EACWWTIHPASKQRSEGEKVRIGDDLILVSVSSERFLHLSMSNGNIQVDASFMQTLWNVQPTCSG-------SNVAV----GYLLGGHVIRLFH----GHDESLTVPGSDQSGE-------QQRVANYEAGKGGSRARSLWRLEPLRISWSGSHIRWGQPFRLRHLSTGHYLGQTEDRGLVLLDREKSDTTATAFCFRPSKEKVDSGSKRDIEGMGVAEIKYGDSVCFIM-HVATGLWLS------YQAP------DAKSSRLGLLK------RRAFLYPEGHMDDGLILQLCQHEESRAARIIRNTTQLFTQFI-RYSISVPVTASEVSLPVGEVMQTLDDLITYFQQPDPDLEHEEKQRQLRSLIKRQDLFKEEVSL-FICRL-LIWVQLSNHLLYIILHATALIQGNRPNCTQFSRKLDWLISK-LERLESSSGILEALHCILTESPEALNIIQKVHIKSIISLLYKHGRNHKILDILCSLCVCNGVAVRTNQ 561          
BLAST of Inositol 1,4,5-trisphosphate receptor type 3 vs. Ensembl Cavefish
Match: ryr1b (ryanodine receptor 1b (skeletal) [Source:ZFIN;Acc:ZDB-GENE-070705-417])

HSP 1 Score: 78.1814 bits (191), Expect = 1.769e-13
Identity = 71/249 (28.51%), Postives = 122/249 (49.00%), Query Frame = 3
Query: 7134 FLYEISLLLSMSIGGIWIPYLYVFHLFNVIHNNQLLKGVIASVTKNGRXXXXXXXXXXXXXXXFSIFAFCFLRSTFS-SENYLYADT---------LVQTFVSLVRFGIVGDLYQYTIPHKY--YMKTVDTAFTEFSXXXXXXXXXXXXXXXXXXXXXXXXXVDTFSELRDLKYKTEKDMKETCFICSRAGHDFDQSSSSFEHHVVYEHNMWAYLFYFLHLKEIKINDYFHLDLYVANMLKRENYDFFP 7844
            FLY +  L+ MS+ G +  + +  HL ++    + L+ +++SVT NG+ L+  + L+ +V+Y++++ AF F R  ++ SE+    D          L   +V +   G +GD  +     +Y  Y    D  F  F             + +  L II G+I+D F ELRD + +  +DM+  CFIC      FD +   FE H + EHN+  Y+F+ ++L      ++   + YV  M +   +DFFP
Sbjct: 4709 FLYLVWYLV-MSLLGHYNNFFFACHLLDIAMGVKTLRTILSSVTHNGKQLMMTVGLLAVVVYLYTVVAFNFFRKFYNMSEDEDEPDMKCDDMMTCYLFHMYVGVRAGGGIGDEIEDPAGDEYELYRVVFDITFFFF-------------VIVILLAIIQGLIIDAFGELRDQQEQVREDMETKCFICGIGSDYFDTTPHGFETHTLEEHNLANYMFFLMYLINKDETEHTGQESYVWKMYQERCWDFFP 4943          

HSP 2 Score: 61.2326 bits (147), Expect = 2.478e-8
Identity = 66/286 (23.08%), Postives = 115/286 (40.21%), Query Frame = 2
Query:  503 KTVHYGDVIQLRHVYTRKYIHVNIAKTSSKDQNSMILNLQSHNLKSA-QFKIVPRYKVKYEGEPVQFMDLVTFESLKAPSHYFH---ASDLYQIDNFFHGAALNLATEQSGFTLIKSASDTHIMEEDNFLRGGDYIQIIHKEIDGYIE-SEGIQGGMKKADIYLRIRKSDKFQTLTNSRLSSSANTFWQVEIEKVRLSTEIGQWSSNFRFRHATNRLYLSVKKDLSVSMTKNATNPNT-----VFRLYPQ--------NIDKLIIPYGRYFR----MEHVLTGTWI 1294
            +T+ YG  I LRH ++  Y+       S  D+ ++ + LQ  +   A  + I P  K + EGE V+  D +   S+ +   Y H   AS    +D  F     N+    SG  L            + FL GG  +++ H  +D  +  S   QG              D+     +  + S A + W++E  ++  S    +W   FR RH +   Y+ + ++  + M  +    NT      FR   +        +++ + IP  +Y      ++HV TG W+
Sbjct:   81 RTLLYGHAILLRHNHSSMYLSCLTTSRSLTDKLAIDVGLQEDSTGEACWWTIHPASKQRSEGEKVRVGDDLILVSVSS-ERYLHLSMASGDLMVDASFMQTLWNMNPVCSGCEL-----------AEGFLTGGHVLRLFHGHMDECLAISPPDQG-------------EDQIAQYESGAVCSQARSLWRLEPLRISWSGGHMKWGQAFRIRHISTGRYVCLDEEKGL-MVLDPEKANTKLSAFCFRASKEKVEVAKKRDVEGMGIPEIKYGESMCFVQHVSTGLWL 340          
BLAST of Inositol 1,4,5-trisphosphate receptor type 3 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000003582.1 (pep scaffold:Pmarinus_7.0:GL477251:10655:41631:-1 gene:ENSPMAG00000003274.1 transcript:ENSPMAT00000003582.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 93.2041 bits (230), Expect = 8.411e-20
Identity = 80/325 (24.62%), Postives = 147/325 (45.23%), Query Frame = 2
Query:  461 EENDNALENRRNLGKTVHYGDVIQLRHVYTRKYIHVNIAKTSSKDQNSMILNLQSHNLKSAQFKIVPRYKVKYEGEPVQFMDLVTFESLKAPSHYFHASDLYQIDNFFHGA----ALNLATEQSGFTLIKSASDTHIMEEDNFLRGGDYIQIIHKEIDGYIESEGIQGGMKKADIYLRIRKSDKFQTLTNSRLSSSANTFWQVEIEKVRLSTE-IGQWSSNFRFRHATNRLYLSVK------KDLSV----------------SMTKNATNPNTVFRLYP------------------QNIDKLIIPYGRYFRMEHVLTGTWIHA 1300
            E+  N  EN++ LG  + YG+V+QL H+ + KY+ VN    +  ++N+M + L     + + F + P YK++  G+ V   D V    + A     HAS+   +DN   G     ++N +T     +L  + S+     +++ L+GGD +++ H E + ++ S+  +   KK  ++LR        + T+S+        W++E+ +     E  G W+S FRF+H     YL+ +      +++SV                S ++++     +F L P                  Q  D L +P   Y R+ H+ T TW+H+
Sbjct:   80 EKKQNESENKKLLGTVIQYGNVVQLLHMKSNKYMTVNKRLPALLEKNAMRVVLNGSGNEGSWFYVQPFYKLRSMGDSVVVGDKVVLNPVNA-GQPLHASNYELVDN--PGCKEVNSVNCSTSWK-ISLFMTWSE----NKEDILKGGDVVRLFHAEQEKFLTSDEYR---KKQHVFLRTTGRQSATSATSSK------ALWEIEVVQHDPCREGAGHWNSLFRFKHLATGDYLAAEVTAWAPRNVSVPPPPRRSQADAEPAASSTSRSSKRDRMMFTLVPVDHGSDIASIFELDPTTMQRGDSL-VPRNSYVRLRHLCTNTWVHS 386          
BLAST of Inositol 1,4,5-trisphosphate receptor type 3 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007822.1 (pep scaffold:Pmarinus_7.0:GL476823:160879:181935:-1 gene:ENSPMAG00000007060.1 transcript:ENSPMAT00000007822.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 85.5001 bits (210), Expect = 4.224e-17
Identity = 43/101 (42.57%), Postives = 64/101 (63.37%), Query Frame = 3
Query: 7584 VDTFSELRDLKYKTEKDMKETCFICSRAGHD---FDQSSSSFEHHVVYEHNMWAYLFYFLHLKEIKINDYFHLDLYVANMLKRENYDFFPINCALSLTAEQ 7877
            +DTF++LR  K K E+ +K TCFIC+ AG +   FD  + SFE H+  EHNMW YL++ + +K     +Y   + YVA M++ EN D+FP   A+SL + +
Sbjct:  308 IDTFADLRSEKQKKEEVLKTTCFICA-AGLERDKFDNKTVSFEEHIKVEHNMWNYLYFIVLIKVKDPTEYTGPESYVAQMIREENVDWFPRMRAMSLVSSE 407          
BLAST of Inositol 1,4,5-trisphosphate receptor type 3 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007816.1 (pep scaffold:Pmarinus_7.0:GL476823:160879:205429:-1 gene:ENSPMAG00000007060.1 transcript:ENSPMAT00000007816.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 85.8853 bits (211), Expect = 1.031e-16
Identity = 43/101 (42.57%), Postives = 64/101 (63.37%), Query Frame = 3
Query: 7584 VDTFSELRDLKYKTEKDMKETCFICSRAGHD---FDQSSSSFEHHVVYEHNMWAYLFYFLHLKEIKINDYFHLDLYVANMLKRENYDFFPINCALSLTAEQ 7877
            +DTF++LR  K K E+ +K TCFIC+ AG +   FD  + SFE H+  EHNMW YL++ + +K     +Y   + YVA M++ EN D+FP   A+SL + +
Sbjct:  763 IDTFADLRSEKQKKEEVLKTTCFICA-AGLERDKFDNKTVSFEEHIKVEHNMWNYLYFIVLIKVKDPTEYTGPESYVAQMIREENVDWFPRMRAMSLVSSE 862          
BLAST of Inositol 1,4,5-trisphosphate receptor type 3 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000010602.1 (pep scaffold:Pmarinus_7.0:GL476450:29:322425:-1 gene:ENSPMAG00000009553.1 transcript:ENSPMAT00000010602.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 63.929 bits (154), Expect = 6.145e-10
Identity = 67/283 (23.67%), Postives = 116/283 (40.99%), Query Frame = 2
Query:  503 KTVHYGDVIQLRHVYTRKYIHVNIAKTSSKDQNSMILNLQSHNLKSA-QFKIVPRYKVKYEGEPVQFMDLVTFESLKAPS--HYFHASDLYQIDNFFHGAALNLATEQSGFTLIKSASDTHIMEEDNFLRGGDYIQIIHKEIDGYIESEGIQGGMKKADIYLRIRKSDKFQTLTNSRLSSSANTFWQVEIEKVRLSTEIGQWSSNFRFRHATNRLYLSVKKDLSVSMTKN--ATNPNTVFRLYP----------QNIDKLIIPYGRY----FRMEHVLTGTWI 1294
            +T+ YG  I LRH ++  Y+       SS D+ +  + LQ      A  + I P  K + EGE V+  D +   S+ +    H  HA+    +D  F     N++   SG  + +            +L GGD +++ H    G+ E   +      AD     R+S  ++      + S A + W++E  +V  S     W   FR RH T   YL++ ++  + +     A    + F +            ++ID +  P  +Y      M+HV +G W+
Sbjct:   83 RTLLYGHAIILRHAHSGMYLSCLRTSHSSSDKLAFDVGLQEDTTGEACWWTIHPASKQRSEGEKVRVGDDLILVSISSERYLHLSHANGSLHVDASFQQTLWNVSPVCSGSEMAQ-----------GYLIGGDVLRLFH----GHDECVTV----PPADRGDEHRRSVHYE---GGAVCSHARSLWRLETLRVSWSGNHLHWGQPFRLRHVTTGKYLALTEERVLLLVDRGCADVKTSAFSMRSSKEKLDSGPRRDIDGMGSPEIKYGDSVCYMQHVESGRWL 343          
BLAST of Inositol 1,4,5-trisphosphate receptor type 3 vs. Ensembl Nematostella
Match: EDO37876 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SEK1])

HSP 1 Score: 105.145 bits (261), Expect = 3.659e-22
Identity = 104/405 (25.68%), Postives = 189/405 (46.67%), Query Frame = 2
Query:  164 MNDYLSYGDRICLYCE-ETNGFINSNNSSSHYNELRIFSKQDKFNPENVSDIQEIIFEVVIQNRXXXXXXXXXXXXDINNKSENLELKIQAEQAKATVISEENDNALENRRNLGKTVHYGDVIQLRHVYTRKYIHVNIAKTSSKDQNSMILNLQSHNLKSAQFKIVPRYKVKYEGEPVQFMDLVTFESLKAPSHYFHASDLYQIDNFFHGAA-LNLATEQSGFTLIKSASDTHIMEEDNFLRGGDYIQIIHKEIDGYIESEGIQGGMKKADIYLRIRKSDKFQTLTNSRLSSSANTFWQVE-IEKVRLSTEIGQWSSNFRFRHATNRLYLSVKKDLSVSMTKNAT-------NP-------------NTVFRLYPQNIDK--LIIPYGRYFRMEHVLTGTWIHAN 1303
            +  +L  GD + LY E    GFI++         ++     D  NP      ++ +F++   NRY   K++ K  K   + ++ + LK     A+     E+  N  E ++ L   V YG V+QL HV + K++ VN    + +++N+M + L  +  + + F IVP YK++  G+ V   D+V    + A     HAS+   IDN   G   +N    Q+ + +  S   ++   +++ L+GGD +++ H E + ++  +  +   KK+ I+LR   +   QT T+   ++S+   W+VE ++        G W+  FRF+H     YL+ + D     TK+AT       +P              ++F L P  + +   ++P   Y R+ H+ T TW+H+ 
Sbjct:    4 VTSFLHIGDIVSLYAEGNVTGFISTLGLIDDRCVVQP-GAGDLSNPPK--KFRDCLFKICPMNRYSAQKQFWKAAKPTTSATDAVLLKKLHHAAEL----EKKQNESEYKKMLSSVVQYGSVMQLLHVKSNKFLTVNKRLPALREKNAMRVTLDPNGNEGSWFYIVPFYKLRAAGDNVVVGDMVILNPVNA-GQPLHASNQELIDN--PGCKEVNCVNCQTSWKI--SLFLSYDENDEDILKGGDVVRLFHAEQEKFLTCDDFK---KKSYIFLR---TTARQTATS---ATSSKALWEVEVVQHDPCRGGAGHWNCLFRFKHLATGDYLAAEAD--DDNTKDATRHKLKGSDPVFHLVPAPHGNDIASIFELDPTTLTRSDSLVPRCSYVRLRHLCTNTWVHST 385          

HSP 2 Score: 87.8113 bits (216), Expect = 7.515e-17
Identity = 82/251 (32.67%), Postives = 128/251 (51.00%), Query Frame = 3
Query: 7191 YLYVFHLFNVIHNNQLLKGVIASVTKNGRXXXXXXXXXXXXXXXFSIFAFCFLRSTF-----------------SSENYLYADTLVQTFVSLVRFGI-----VGDLYQYTIPHKYYMKTVDTAFTEFSXXXXXXXXXXXXXXXXXXXXXXXXXVDTFSELRDLKYKTEKDMKETCFICSRAGHDFDQSSSSFEHHVVYEHNMWAYLFYFLHLKEIKINDYFHLDLYVANMLKRENYDFFPINCALSLTAEQ 7877
            + Y   L +VI     L  VI SVT+NGR +I   IL +I++Y+FSI  F FL+  F                  S      DTL+   V+ +  G+     +GD+          ++   +    F+  +++ L FF  + I  LN+IFG+I+DTF++LR  K   E+ +K TCFIC      FD  S SF+ H+  +HNMW YL+Y + L+     ++   + YV++M K +N D+FP   A+SL  ++
Sbjct: 2318 FFYSVLLLDVIFREDTLLNVIRSVTRNGRSIILTGILALIIVYMFSIVGFLFLKDDFLIETDPPPALPSIGEGGESVKERACDTLIMCIVTTLNQGLRNGGGIGDV----------LRRRSSKEKMFAGRVVYDLMFFFIVIIIVLNLIFGVIIDTFADLRSEKQNKEEVLKNTCFICGLDRSAFDNKSVSFDEHIKSQHNMWHYLYYIVLLRVKDPTEFTGPESYVSHMTKDKNLDWFPRMQAMSLAIDE 2558          

HSP 3 Score: 53.5286 bits (127), Expect = 1.748e-6
Identity = 81/372 (21.77%), Postives = 175/372 (47.04%), Query Frame = 2
Query: 5891 VKLILQLLSRMCVGQYQGLQNYLRIQPDNRSSVDVISLIVQFLGNIYAN-----------VRQSTIDLSIQAFDTIKETIMGN-QENRSVVYR--AKVVDYANFILRNDEISETCDPNNVLQMFLVI------GRVIMALIEENGREETELAKEIQITLDIKAVFKIMTRCL---DMMEDTKRKLIKNKIYDVGFTYFLILARL----EDLCNGKLLKHFQISDQQM---KAXXXXXXGSASVEILKGDQ-LQRIHFRLKH-KEVLRESVKEKVKWEVDRTTPSNKIRSFISWSKLILPDMNFQRKIIQNPLLLFVTKQ---WNAMNY-FLTLLSLVINILY**G*RPLIKDILI*LGPFRLDIRISTITLL 6898
            +K IL+ L  +C    + LQNY+R Q +N+++ +++   +QFL  I  +           + ++ ++L  Q  +++ E   G   +N+  + R  +  +D    ++ ND      +P    +M LV+       + ++A++E   R ++E A+ I   +  K +  +  +     DM+E+   ++      DVG   +L+  +L    ++L +   L H +   +Q+    A +++ K +A +EI++ D+ +++I F +    E L +  K  V    +R   ++K+  F   ++ +  +M +Q+K+ ++ LL  ++ +   W  ++  F  L++L++   Y     P         GP  LD R+S +  L
Sbjct: 1872 MKPILRFLQLLCENHNRDLQNYIRRQDNNKANYNLVHETLQFLDCICGSTSGGLGLLGLYINENNVELINQCLESLTEYCQGPCHDNQDAIARHESNGIDIIIALVLND-----INPLGKQRMDLVLELKNTASKTLLAVMES--RHDSENAERILYNMTPKQLVDVCKQAYQQDDMVEEDDSEV---SARDVGHNIYLLATQLSQHNKELASLLKLTHTEFEMEQIHGDSALEYYAKNTAQIEIVRQDRTMEQIVFPVPQICEFLTDESKINVYATCERDDQNSKVSDFFHRTEDLFQEMQWQKKLREHRLLFGLSSRLSLWEQISINFAVLINLLVGFFY-----PFSD------GPGDLDPRLSILVWL 2222          
BLAST of Inositol 1,4,5-trisphosphate receptor type 3 vs. Ensembl Nematostella
Match: EDO28592 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T616])

HSP 1 Score: 80.4925 bits (197), Expect = 7.245e-15
Identity = 90/312 (28.85%), Postives = 147/312 (47.12%), Query Frame = 3
Query: 7191 YLYVFHLFNVIHNNQLLKGVIASVTKNGRXXXXXXXXXXXXXXXFSIFAFCF--------------LRSTFSSENYLYA---------------DTLVQTFVSLVRFGI-----VGDLYQYTIPHKYYMKTVDTAFTEFSXXXXXXXXXXXXXXXXXXXXXXXXXVDTFSELRDLKYKTEKDMKETCFICSRAGHDFDQSSSSFEHHVVYEHNMWAYLFYFLHLKEIKINDYFHLDLYVANMLKRENYDFFPINCALSLTAEQ------EKYSRIDEISRNVKII---------VSNRQNEEREKLRRTNLF 7979
            + Y   L +VI     L  VI SVT+NGR +I   IL +I++Y+FSI  F F              L S  S    + A               DTL+   V+ +  G+     +GD+          ++   +    F+  +++ L FF  + I  LN+IFG+I+DTF++LR  K   E+ +K TCFIC      FD  S SF+ H+  +HNMW YL+Y + L+     ++   + YV++M K +N D+FP   A+SL  ++      E  +  D++    K++         +  +  E+R++ +R  L 
Sbjct:  454 FFYSVLLLDVIFREDTLLNVIRSVTRNGRSIILTGILALIIVYMFSIVGFLFLKDDFLIETDPPPALPSIGSPRGGVCASSGGEGGESVKERACDTLIMCIVTTLNQGLRNGGGIGDV----------LRRRSSKEKMFAGRVVYDLMFFFIVIIIVLNLIFGVIIDTFADLRSEKQNKEEVLKNTCFICGLDRSAFDNKSVSFDEHIKSQHNMWHYLYYIVLLRVKDPTEFTGPESYVSHMTKDKNLDWFPRMQAMSLAIDEGGNEQNEMRNLQDKLENTTKLVQTLSQQLSDLKEQMTEQRKQKQRMGLL 755          
BLAST of Inositol 1,4,5-trisphosphate receptor type 3 vs. Ensembl Medaka
Match: itpr1b (inositol 1,4,5-trisphosphate receptor type 1 [Source:NCBI gene;Acc:101155104])

HSP 1 Score: 132.88 bits (333), Expect = 4.000e-30
Identity = 168/696 (24.14%), Postives = 296/696 (42.53%), Query Frame = 2
Query:  152 IFQLMNDYLSYGDRICLYCE-ETNGFINSNNSSSHYNELRIFSKQDKFNPENV-SDIQEIIFEVVIQNRXXXXXXXXXXXXDINNKSENLELKIQAEQAKATVISEENDNALENRRNLGKTVHYGDVIQLRHVYTRKYIHVNIAKTSSKDQNSMILNLQSHNLKSAQFKIVPRYKVKYEGEPVQFMDLVTFESLKAPSHYFHASDLYQIDNFFHGA----ALNLATEQSGFTLIKSASDTHIMEEDNFLRGGDYIQIIHKEIDGYIESEGIQGGMKKADIYLRIRKSDKFQTLTNSRLSSSANTFWQVE-IEKVRLSTEIGQWSSNFRFRHATNRLYLSV-----------------------KKDLSVSMTKNATNPNTVFRLYPQNI--DKLIIPYGRYFRMEHVLTGTWIHANKEQVYVKPNQSKYDDAAEKCLGNLKYETNELRELFCVHQRLYDDAFVVFKVPTEIVESFNLLSGYFPLIKNLIVDRKKAVPFTASQSYRYKLALEEI-----------RDSL-YLDGKPHSLRQKHLRNLQIVDLLVELVLLPFHSKIDAAFT-------------EKIYRASFEILHNYMKGSSIKNSLYFAKYINLFEPKMLENNDLGHKII--EMIAELLRNNQKVLE-CISFQEIFPFIDNLRINQNFRYLEYLETFCVCNGE--PMTQNQIKIAV 2053
            I   M+ +L  GD   LY E  T+GFI    S+    + R   + D  +  N     ++ +F++   NRY   K++ K  K   N + +  L  +   A      E+  N  ENR+ LG  + YG+VIQL H+ + KY+ VN    +  ++N+M + L S   + + F I P YK++  G+ V   D V    + A     HAS    +DN   G     ++N  T       +K + +     ++  L+GGD +++ H E + ++  +  +   KK  ++LR   +   Q+ T+   ++S+   W+VE + +       G W+S FRF+H     YL+                        K   ++    +    +++F L P  +     ++P   Y R++H+ T TW+H+    +          D  E+    L+  T+E++E          +AF +  VP   V   +  +    ++ ++    +K       + +  KL LE++           +D L  +  KP+  RQK +R   I+  + +L+  PF    D                   I R  + +L +  +    KN  Y AK     + +      +G+ ++  + I  LL NN+K+LE  I+  EI  F+  +R N+  R+L+YL   CV   +  P+TQ  I  AV
Sbjct:    1 IMDKMSSFLHIGDICSLYAEGSTSGFI----STLGLVDDRCVVQPDAGDLNNPPKKFRDCLFKLCPMNRYSAQKQFWKAAKPGGNSTTDTVLLNKLHHAADL---EKKQNESENRKLLGTVIQYGNVIQLLHLKSNKYLTVNKRLPALLEKNAMRVTLDSAGNEGSWFYIQPFYKLRSLGDSVVIGDKVVLNPVNA-GQPLHASSHQLVDN--PGCNEVNSVNCNTSWKVVLFMKWSDN-----KETILKGGDVVRLFHAEQEKFLTCDDHK---KKQHVFLR---TTGRQSATS---ATSSKALWEVEVVHRDPCRGGAGYWNSLFRFKHLATGCYLAAEVNPDFEEENNEALRGRLRTPQEKVMCTLVPVPDGMEISSIFELDPTTLRGGDSMVPRSSYVRLKHLFTNTWVHSTNNPI----------DKEEEKPVMLRIGTSEVKE--------DKEAFAIVPVPPAEVRDLDFANDASKVLASIAGKLEKGTITQNERRFVTKL-LEDLVFFVVDIPNSGQDVLEIMVNKPNRERQKLMREQNILKQIFKLLQAPFTDSGDGPMLRLEELGDQRHAPFRHICRLCYRVLRHSQQDYR-KNQEYIAKQFRFMQKQ------IGYDVLAEDTITALLHNNRKLLEKHITAAEIDTFVTLVRKNREPRFLDYLSDLCVSMSKSIPVTQELICNAV 646          

HSP 2 Score: 85.8853 bits (211), Expect = 7.905e-16
Identity = 49/147 (33.33%), Postives = 76/147 (51.70%), Query Frame = 3
Query: 7584 VDTFSELRDLKYKTEKDMKETCFICSRAGHDFDQSSSSFEHHVVYEHNMWAYLFYFLHLKEIKINDYFHLDLYVANMLKRENYDFFPINCALSLT-----AEQEKYSRIDEISRNVKIIVSN----------RQNEEREKLRRTNLF 7979
            +DTF++LR  K K E+ +K TCFIC      FD  + +FE H+  EHNMW YLF+ + +K     +Y   + YVA M++  N D+FP   A+SL       EQ +   + E   +   +V+N          +  E+R++ +R  L 
Sbjct: 2467 IDTFADLRSEKQKKEEILKTTCFICGLERDKFDNKTVTFEEHIKVEHNMWHYLFFIVLVKVKDSTEYTGPESYVAEMIREHNLDWFPRMRAMSLVSSDADGEQNEIRNLQEKLESTMKLVTNLSSQLTELKEQMTEQRKQKQRIGLL 2613          
BLAST of Inositol 1,4,5-trisphosphate receptor type 3 vs. Ensembl Medaka
Match: itpr1a (inositol 1,4,5-trisphosphate receptor type 1 [Source:NCBI gene;Acc:101167700])

HSP 1 Score: 115.931 bits (289), Expect = 5.263e-25
Identity = 214/949 (22.55%), Postives = 399/949 (42.04%), Query Frame = 2
Query:  164 MNDYLSYGDRICLYCE-ETNGFINSNNSSSHYNELRIFSKQDKFNPENVSD-IQEIIFEVVIQNRXXXXXXXXXXXXDINNKSENLELKIQAEQAKATVISEENDNALENRRNLGKTVHYGDVIQLRHVYTRKYIHVNIAKTSSKDQNSMILNLQSHNLKSAQFKIVPRYKVKYEGEPVQFMDLVTFESLKAPSHYFHASDLYQIDNFFHGA----ALNLATEQSGFTLIKSASDTHIMEEDNFLRGGDYIQIIHKEIDGYIESEGIQGGMKKADIYLRIRKSDKFQTLTNSRLSSSANTFWQVE-IEKVRLSTEIGQWSSNFRFRHATNRLYL------------------SVKKDLSVSMTK---------NATNPNTVFRLYPQNI--DKLIIPYGRYFRMEHVLTGTWIHANKEQVYVKPNQSKYDDAAEKCLGNLKYETNELRELFCVHQRLYDDAFVVFKVPTEIVESFNLLSGYFPLIKNLIVDRKKAVPFTASQSYRYKLA--LEEI-----------RDSLYLDGKPHSL-RQKHLRNLQIVDLLVELVLLPFHSKIDA-------------AFTEKIYRASFEILHNYMKGSSIKNSLYFAKYINLFEPKMLENNDLGHKII--EMIAELLRNNQKVLE-CISFQEIFPFIDNLRINQNFRYLEYLETFCVCNGE--PMTQNQIKIAVKWLSEDQRGVFLTDRG-------QNLNLESNVIYIKTKLDSNWMKLHEFLDITAQIDQENNPLYHQDNKD----------YFLKQMDLLLALCYGRNQYCTNLIINKLNYISWEQCFAAINSPMIPPYMKTKYFEIIQTMFIDIGRNYAVIESP-KFNFIFNQIQGDSSVAVECMFPTPSESVTIKIFKDLSEWIYNFLES--TPRMISSNKDFNYLIRIVFITINKLIQYGYYDSPSLDRICKSLLKLLN 2746
            M+ +L  GD   LY E  TNGFI    S+    + R   + D  +  N     ++ +F++   NRY   K++ K  K   N    L  K+      A +  ++ND+  EN++ LG  + YG+VIQL H+ + KY+ VN    +  ++N+M + L +   + + F I P YK++  G+ V   D V    + A     HAS    +DN   G     ++N  T       +K   +  ++     L+GGD +++ H E + ++  +  +   KK  ++LR   +   Q+ T+   ++S+   W+VE ++        G W+S FRF+H     YL                  +++  L  +  K         +  + +++F L P  +     ++P   Y R+ H+ T TW+H+  + +          D  E+    L+  T+  +E          +AF +  V    V   +  +    ++ ++    +K    T +Q+ R  +   LE++           +D L +    H+  RQK +R   I+  + +L+  PF    D              A    I R  + +L +  +    KN  Y AK     + +      +G+ ++  + I  LL NN+K+LE  I+  EI  F++ +R N+  R+L+YL   CV   +  P+TQ  I  AV  L      + +  +        Q + L  N +  +   +  W+   E  +   +I  ++     QD K+          Y+  Q++L   +C  R     N I  +L+     +C +  +   +P  ++  +  ++  M +D  R+     +P K+  ++++I    S+       T  + +  + F    E++  +L +  +P +   NK+ N L   V      LI +G+Y+   L R+ K LL +L+
Sbjct:    5 MSSFLHIGDICSLYAEGSTNGFI----STLGLVDDRCVVQPDAGDLNNPPKKFRDCLFKLCPMNRYSAQKQFWKAAKPGGNTDTVLLNKLHH---AADLEKKQNDS--ENKKLLGSVIQYGNVIQLLHLKSNKYLTVNKRLPALLEKNAMRVMLDTAGNEGSWFYIQPFYKLRSIGDSVVIGDKVVLNPVNA-GQPLHASSHQLVDN--PGCNEVNSVNCNTSWKIVLFMKWGDNQEVV-----LKGGDVVRLFHAEQEKFLTCDDHR---KKQYVFLR---TTGRQSATS---ATSSKALWEVEVVQHDPCRGGAGYWNSLFRFKHLATGHYLAAEVNPEYEEERPDNQHEALRARLRCAQEKVMYALVAVPDGNDISSIFELDPTTLRGGDSLVPRNSYVRLRHLCTNTWVHSTNQPI----------DKEEEKPVMLRIGTSPHKE--------DKEAFAIVPVSPAEVRDLDFANDASKVLASIAGKLEKG---TITQNERRAVTKLLEDLVFFVVDIPNNGQDVLEIMVNKHNRERQKVMREQNILKQIFKLLQAPFTDSGDGPMLRLEELGDQRHAPFRHICRLCYRVLRHSQQDYR-KNQEYIAKQFRFMQKQ------IGYDVLAEDTITALLHNNRKLLEKHITAAEIDTFVNLVRKNREPRFLDYLSDLCVSMNKSIPVTQELICNAV--LDPANADILIETKLVLSRFEIQGVPLGENSVESEEDEEEVWLFWKE--NNKKEIRSKSIRELAQDAKEGQKEDKEVISYYRYQLNLFARMCLDRQYLAINKISCQLDVDLILRCMSDED---LPFDLRASFCRMMLHMHVD--RDPQEQVTPVKYARLWSEIPLKISIEDYDNDGTSKDEIKER-FSQTMEFVETYLRNVVSPNLSFGNKEKNKLTFEVVNLARNLIYFGFYNFSDLLRLTKILLGILD 889          

HSP 2 Score: 84.3445 bits (207), Expect = 2.151e-15
Identity = 47/147 (31.97%), Postives = 79/147 (53.74%), Query Frame = 3
Query: 7584 VDTFSELRDLKYKTEKDMKETCFICSRAGHDFDQSSSSFEHHVVYEHNMWAYLFYFLHLKEIKINDYFHLDLYVANMLKRENYDFFPINCALSLTA------EQEKYSRIDEISRNVKII---------VSNRQNEEREKLRRTNLF 7979
            +DTF++LR  K K E+ +K TCFIC      FD  + +FE H++ EH+MW YL++ + +K     +Y   + YVA M+K  N D+FP   A+SL +      + E  S  D++   +K++         +  +  E+R++ +R  L 
Sbjct: 2504 IDTFADLRSEKQKKEEVLKTTCFICGLERDKFDNKTVTFEEHIMEEHSMWHYLYFIVLVKVKDSTEYTGPESYVAQMIKEHNLDWFPRMRAMSLVSSDGEGEQNEIRSLQDKLDSTMKLVANLSGQLTELKEQMTEQRKQKQRIGLL 2650          
BLAST of Inositol 1,4,5-trisphosphate receptor type 3 vs. Ensembl Medaka
Match: itpr3 (inositol 1,4,5-trisphosphate receptor type 3 [Source:NCBI gene;Acc:101170574])

HSP 1 Score: 102.449 bits (254), Expect = 6.846e-21
Identity = 99/284 (34.86%), Postives = 157/284 (55.28%), Query Frame = 3
Query: 7134 FLYEISLLLSMSIGGIWIPYL-YVFHLFNVIHNNQLLKGVIASVTKNGRXXXXXXXXXXXXXXXFSIFAFCFLRSTFSSE-----NYLYA-DTLVQTFVSLVRFGI-----VGDLYQYTIPHKYYMKTVDTAFTEFSXXXXXXXXXXXXXXXXXXXXXXXXXVDTFSELRDLKYKTEKDMKETCFICSRAGHDFDQSSSSFEHHVVYEHNMWAYLFYFLHLKEIKINDYFHLDLYVANMLKRENYDFFPINCALSLTAE----QEKYSRI--DEISRNVKIIVS 7931
            FLY ++ +L+ SI G++I  L Y   LF++I+  + L  VI SVT+NGR ++   +L +I++Y+FSI  F  L+  F  E     N   A DTL+   V+++  G+     VGD+ +         K        F   +++ L F+  + I  LN+IFG+I+DTF++LR  K K E+ +K TCFIC      FD  + SFE H+  EHN+W YL++ + L+E    DY   + YVA+M+K  N D+FP   A+SL       ++   RI  D++   +K++ +
Sbjct: 1996 FLYHLAYVLT-SILGLFIHELFYSILLFDLIYREETLFNVIKSVTRNGRSILLTALLALILVYLFSIVGFLCLKEDFIMEVDPESNLERACDTLLMCIVTVLNHGLRNGGGVGDVLR---------KPSKDQEPLFPARVVYDLLFYFIVIIIVLNLIFGVIIDTFADLRSEKQKKEEILKTTCFICLERDK-FDNKTVSFEEHINMEHNIWNYLYFIVLLREKNKTDYTGPESYVAHMMKNNNLDWFPRMQAMSLVVTDSDGEQNEMRILQDKLGSTMKVVTT 2268          

HSP 2 Score: 64.6994 bits (156), Expect = 1.728e-9
Identity = 67/300 (22.33%), Postives = 127/300 (42.33%), Query Frame = 2
Query:  509 VHYGDVIQL--------------RHVYTRKYIHVNIAKTSSKDQNSMILNLQSHNLKSAQFKIVPRYKVKYEGEPVQFMDLVTFESLKAPSHYFHASDLYQIDNFFHGAALNLATEQSGF--TLIKSASDTHIMEEDNFLRGGDYIQIIHKEIDGYIESEGIQGGMKKADIYLRIRKSDKFQTLTNSRLS-SSANTFWQVEI---EKVRLSTEIGQWSSNFRFRHATNRLYLSVKKD--------------LSVSMTKNATNPNTVFRLYPQNIDKL--IIPYGRYFRMEHVLTGTWIHA 1300
            +H GD++ L               H+ + KY+ VN    +  ++N+M + L     + +   I P +K++  G+ V   D V    + A     HAS+ Y +++      +N     + +   L    SD      ++ L+GGD +++ H E + ++  +  +    K  ++LR        TL  S  S +S+N  W++E+   +  R     G W+S +RF+H     YL+ + D                + +  +  +  ++F L P  + K    +P   Y R+ H+ T TWI +
Sbjct:    9 LHIGDIVSLYAEGSVNGFISTLLLHMKSNKYLTVNKRLPALLEKNAMRVTLDGTGNEGSWLFIQPFWKLRANGDNVLVGDKVILNPVNA-GQPLHASN-YDLNDHSGCKEVNSVNCNTSWKINLFMMFSD----HREDVLKGGDVVRLFHAEQEKFLTCDEYKS---KLHVFLRT-------TLRQSATSATSSNALWEIEVVHHDPCRGGA--GHWNSLYRFKHLATGNYLAAEMDGRRISKRSQGERIKYKLVVLSDGNDIASLFELDPTTLQKTDSFVP-NSYVRLRHLCTNTWIQS 289          
BLAST of Inositol 1,4,5-trisphosphate receptor type 3 vs. Ensembl Medaka
Match: ENSORLT00000014249.2 (pep primary_assembly:ASM223467v1:6:21638618:21648331:1 gene:ENSORLG00000026619.1 transcript:ENSORLT00000014249.2 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 92.4337 bits (228), Expect = 3.481e-18
Identity = 128/533 (24.02%), Postives = 227/533 (42.59%), Query Frame = 2
Query:  605 MILNLQSHNLKSAQFKIVPRYKVKYEGEPVQFMDLVTFESLKAPSHYFHASDLYQIDNFFHGA--ALNLATEQSGFTLIKSASDTHIMEEDNFLRGGDYIQIIHKEIDGYIESEGIQGGMKKADIYLRIRKSDKFQTLTNSRLSS-SANTFWQVEI---EKVRLSTEIGQWSSNFRFRHATNRLYLSVKKDLS-----------------VSMTKNATNPNTVFRLYPQNIDKLIIPYGR--YFRMEHVLTGTW-------IHANKEQ---VYVKPNQSKYDDAAEKCLGNLKYETNELRELFCVHQRLYDDAFVVFKVPTEIVESFNLLSGYFPLIKNLIVDRKKAVPFTASQSYRYKLALEEIRDSLYL-DGKPHSLRQKHLRNLQIVDLLVELVLLPFHSKIDAAF-------------TEKIYRASFEILHNYMKGSSIKNSLYFAKYINLFEPKMLENNDLGHKII--EMIAELLRNNQKVLEC-ISFQEIFPFIDNLRINQNFRYLEYLETFCVCN--GEPMTQNQI 2041
            M ++L     + + F I P +K++ EG+ V   D V    + A     HAS++  +DN       A+N  T     TL    SD      ++ L+GGD +++ H E + ++  +G +   ++  ++LR        TL  S  S+ S+   W+VE+   +  R     G W+S FRF+H     YL+ +  L+                   ++   ++  ++F L P  + +   P  R  Y R+ H+ T TW       I A +E+   + +   +SK D  A      +    +E+R+L        +DA  V +   + +++ NL       +  L+ D    V    +            +D L +    P+  RQK +R   I+  +  ++  PF    + A               + I +  + +L +  +    KN  Y AK  ++ +      + +G++I+  + I  LL NN+K+LE  I+ +EI  F++ LR N+  RYL+YL   CV N    P+TQ  I
Sbjct:    1 MRVSLDPAGNEGSWFYIQPFWKLRSEGDNVVVGDKVVLMPVNA-GQPLHASNIELLDNLGCKEVNAVNCNTSWK-VTLFMKFSDYR----EDVLKGGDVVRLFHAEQEKFLTCDGYK---RQQHVFLRT-------TLRQSATSATSSKALWEVEVVHYDPCRGGA--GHWNSLFRFKHLATGNYLAAEVCLTPRDASFFYHQAAERIAYTLVSLPGSDIASLFELDPTTLQRTDCPVPRNSYVRLRHLCTNTWVTSTNFPIDAEEERPVMLKIGTCRSKEDKEA---FAIVSVPLSEVRDL-----DFANDASKVLEATVKKIQNDNLPQNERRFVTKLLEDLVFFVCVVPNNG----------QDVLSVATSSPNRERQKLMREQNILAQIFGILEAPFIDNGEGAMLKLEQLGDQRYAHIKYILKLCYRVLRHSQQDYR-KNQEYIAKNFSIMQ------SQIGYEILAEDTITALLHNNRKLLEQHITAREIETFVNQLRRNREPRYLDYLSDLCVSNKMAIPVTQELI 490          
BLAST of Inositol 1,4,5-trisphosphate receptor type 3 vs. Ensembl Medaka
Match: itpr2 (inositol 1,4,5-trisphosphate receptor, type 2 [Source:ZFIN;Acc:ZDB-GENE-050419-192])

HSP 1 Score: 92.4337 bits (228), Expect = 6.436e-18
Identity = 89/302 (29.47%), Postives = 148/302 (49.01%), Query Frame = 3
Query: 7128 FVFLYEISLLLSMSIGGIWIPYLYVFHLFNVIHNNQLLKGVIASVTKNGRXXXXXXXXXXXXXXXFSIFAFCFLRSTF-------------SSENYL-----------YADTLVQTFVSLVRFGI-----VGDLYQYTIPHKYYMKTVDTAFTEFSXXXXXXXXXXXXXXXXXXXXXXXXXVDTFSELRDLKYKTEKDMKETCFICSRAGHDFDQSSSSFEHHVVYEHNMWAYLFYFLHLKEIKINDYFHLDLYVANMLKRENYDFFPINCALSLTA-----EQEKYSRIDEISRNVKIIVS 7931
             +F+Y ++  +   +G     + Y F LF+++   + L  VI SVT+NGR +    +L + ++Y FSI  F FL+  F             S +  L             DTL+   ++++  G+     VGD+ +   P K            F+  +++ L FF  + I  LN+IFG+I+DTF++LR  K + E+ +K TCFIC      FD  + +FE H+  EHNMW YL++ + +K     +Y   + YVA M+  +N ++FP   A+SL +     EQ +   + E   N   ++S
Sbjct: 1259 MLFVYHLAYAIICVLGLFVHEFFYSFLLFDLVSREETLLNVIKSVTRNGRSIFLTAVLAIFLVYFFSIIGFLFLKDDFRMEVDPLPLPGHPSQDTCLCERCEDDGMERVCDTLLMCIITVLNQGLRNGGGVGDILRR--PSKEE--------PLFAARVVYDLLFFFVVIIIVLNLIFGVIIDTFADLRSEKQRKEEILKTTCFICGLERDKFDNKTVTFEEHIKSEHNMWHYLYFLVLVKVKDPTEYTGPESYVAQMIAEKNLEWFPRMRAMSLVSNEGDNEQNEMRSLQEKLTNTVTLIS 1550          
BLAST of Inositol 1,4,5-trisphosphate receptor type 3 vs. Planmine SMEST
Match: SMESG000070557.1 (SMESG000070557.1)

HSP 1 Score: 4465.22 bits (11580), Expect = 0.000e+0
Identity = 2205/2214 (99.59%), Postives = 2205/2214 (99.59%), Query Frame = 2
Query:  164 MNDYLSYGDRICLYCEETNGFINSNNSSSHYNELRIFSKQDKFNPENVSDIQEIIFEVVIQNRXXXXXXXXXXXXDINNKSENLELKIQAEQAKATVISEENDNALENRRNLGKTVHYGDVIQLRHVYTRKYIHVNIAKTSSKDQNSMILNLQSHNLKSAQFKIVPRYKVKYEGEPVQFMDLVTFESLKAPSHYFHASDLYQIDNFFHGAALNLATEQSGFTLIKSASDTHIMEEDNFLRGGDYIQIIHKEIDGYIESEGIQGGMKKADIYLRIRKSDKFQTLTNSRLSSSANTFWQVEIEKVRLSTEIGQWSSNFRFRHATNRLYLSVKKDLSVSMTKNATNPNTVFRLYPQNIDKLIIPYGRYFRMEHVLTGTWIHANKEQVYVKPNQSKYDDAAEKCLGNLKYETNELRELFCVHQRLYDDAFVVFKVPTEIVESFNLLSGYFPLIKNLIVDRKKAVPFTASQSYRYKLALEEIRDSLYLDGKPHSLRQKHLRNLQIVDLLVELVLLPFHSKIDAAFTEKIYRASFEILHNYMKGSSIKNSLYFAKYINLFEPKMLENNDLGHKIIEMIAELLRNNQKVLECISFQEIFPFIDNLRINQNFRYLEYLETFCVCNGEPMTQNQIKIAVKWLSEDQRGVFLTDRGQNLNLESNVIYIKTKLDSNWMKLHEFLDITAQIDQENNPLYHQDNKDYFLKQMDLLLALCYGRNQYCTNLIINKLNYISWEQCFAAINSPMIPPYMKTKYFEIIQTMFIDIGRNYAVIESPKFNFIFNQIQGDSSVAVECMFPTPSESVTIKIFKDLSEWIYNFLESTPRMISSNKDFNYLIRIVFITINKLIQYGYYDSPSLDRICKSLLKLLNGRNDLPFEYDSKKESLKIRKKLVTKYKNISRYEDSEETRAIVAAKLSGLEILDSILIYERVSVVAKLISRFKKCVQPDLKVQKKRLTGHTHLEACLSNGFDVAQQYKQSNRATKKMVSEIDNLFTTARFLDSEPWTNILIDLAHYQNEMMTQKSLLILHKLYSIKESSFQDTYATFISKTKQSQDLQELMCEYIPALRLHTKSLIGPPDLEKIAAMITEMINVCKIPKSDSFNPISQRIIVGYGILDIAMETIAQIYRSFDRSKMMYGASEVISLITNLLRHLAISNPSFQEXXXXXXXXXXXXYEHSPPAELADLLRCGLFHNNRTFCGTLKSFQINKIVLMVADTARKNPLVGAAFIHLLESIVAVNNGEVPLKRNQLMVMKFVMKSFNQLVYILDSKSMSRVDLLTIHSASNDAFYFTKVIDLFIACCQGENQYVQSLCQTIMPLDELFDLLTHNDISIIYKRGLLKYFSKVYLSRTNISNQEGIIKNFIESKYCGEILDSIERTTLLTQIILDKTEHFNLLPILKKEFILKPPTEFQVSENIQMHLHYIIFGSSIFMASLCSAFSIMEISPAPELMKVIKSINHITMDIFSQMWKFQLHPSVFSVITESVLQIISYTDTSDLEAKTMALQHCKPQIMDFDPRKEIDNLYTEEIELNLKLQTFIFNCSQLIAGQNTVKAQIKANLRKQYVNLLDQNALPLNLEYQNHLKCFINNSYQKGEIRRYKLVDILIRQLEISGSVERNGKRHTKLDRNSFSKTIKRLDQDALDLRSLQILRGLIYNEECLLPDNWELKIFNSSVQDILKCIKNVQNCLNKLNLSSRTQIHMVNSCDLVKREAITLQSAMLMNANKNVQESLLRYFKGAQEEVFFSAIKYQLQNAFTDLKDQKLMLSQKKSFGDIEKYTCHESDLRIDNLAHILYQQLAEYEIRYEDQNRSLAINRYAYTTTKESFTTRHMRQIYTPAKMKSEINSSSPLICCPRNSSKSNYDMRSTDKSDSLFKNNLQDEYELKSVVTKESNSSTDKTIENSAWIKGETLDLMRNDPHQNVKLILQLLSRMCVGQYQGLQNYLRIQPDNRSSVDVISLIVQFLGNIYANVRQSTIDLSIQAFDTIKETIMGNQENRSVVYRAKVVDYANFILRNDEISETCDPNNVLQMFLVIGRVIMALIEENGREETELAKEIQITLDIKAVFKIMTRCLDMMEDTKRKLIKNKIYDVGFTYFLILARLEDLCNGKLLKHFQISDQQMKAXXXXXXGSASVEILKGDQLQRIHFRLKHKEVLRESVKEKVKWEVDRTTPSNKIRSFISWSKLILPDMNFQRKIIQNPLLLFVTKQWNAMNYFLTLLSLVINIL 6805
            MNDYLSYGDRICLYCEETNGFINSNNSSSHYNELRIFSKQDKFNPENVSDIQEIIFEVVIQNRYKLYKKYMKNYKDINNKSENLELKIQAEQAKATVISEENDNALENRRNLGKTVHYGDVIQLRHVYTRKYIHVNIAKTSSKDQNSMILNLQSHNLKSAQFKIVPRYKVKYEGEPVQFMDLVTFESLKAPSHYFHASDLYQIDNFFHGAALNLATEQSGFTLIKSASDTHIMEEDNFLRGGDYIQIIHKEIDGYIESEGIQGGMKKADIYLRIRKSDKFQTLTNSRLSSSANTFWQVEIEKVRLSTEIGQWSSNFRFRHATNRLYLSVKKDLSVSMTKNATNPNTVFRLYPQNIDKLIIPYGRYFRMEHVLTGTWIHANKEQVYVKPNQSKYDDAAEKCLGNLKYETNELRELFCVHQRLYDDAFVVFKVPTEIVESFNLLSGYFPLIKNLIVDRKKAVPFTASQSYRYKLALEEIRDSLYLDGKPHSLRQKHLRNLQIVDLLVELVLLPFHSKIDAAFTEKIYRASFEILHNYMKGSSIKNSLYFAKYINLFEPKMLENNDLGHKIIEMIAELLRNNQKVLECISFQEIFPFIDNLRINQNFRYLEYLETFCVCNGEPMTQNQIKIAVKWLSEDQRGVFLTDRGQNLNLESNVIYIKTKLDSNWMKLHEFLD       ENNPLYHQDNKDYFLKQMDLLLALCYGRNQYCTNLIINKLNYISWEQCFAAINSPMIPPYMKTKYFEIIQTMFIDIGRNYAVIESPKFNFIFNQIQGDSSVAVECMFPTPSESVTIKIFKDLSEWIYNFLESTPRMISSNKDFNYLIRIVFITINKLIQYGYYDSPSLDRICKSLLKLLNGRNDLPFEYDSKKESLKIRKKLVTKYKNISRYEDSEETRAIVAAKLSGLEILDSILIYERVSVVAKLISRFKKCVQPDLKVQKKRLTGHTHLEACLSNGFDVAQQYKQSNRATKKMVSEIDNLFTTARFLDSEPWTNILIDLAHYQNEMMTQKSLLILHKLYSIKESSFQDTYATFISKTKQSQDLQELMCEYIPALRL TKSLIGPPDLEKIAAMITEMINVCKIPKSDSFNPISQRIIVGYGILDIAMETIAQIYRSFDRSKMMYGASEVISLITNLLRHLAISNPSFQENLFNNLDTLLDLYEHSPPAELADLLRCGLFHNNRTFCGTLKSFQINKIVLMVADTARKNPLVGAAFIHLLESIVAVNNGEVPLKRNQLMVMKFVMKSFNQLVYILDSKSMSRVDLLTIHSASNDAFYFTKVIDLFIACCQGENQYVQSLCQTIMPLDELFDLLTHNDISIIYKRGLLKYFSKVYLSRTNISNQEGIIKNFIESKYCGEILDSIERTTLLTQIILDKTEHFNLLPILKKEFILKPPTEFQVSENIQMHLHYIIFGSSIFMASLCSAFSIMEISPAPELMKVIKSINHITMDIFSQMWKFQLHPSVFSVITESVLQIISYTDTSDLEAKTMALQHCKPQIMDFDPRKEIDNLYTEEIELNLKLQTFIFNCSQLIAGQNTVKAQIKANLRKQYVNLLDQNALPLNLEYQNHLKCFINNSYQKGEIRRYKLVDILIRQLEISGSVERNGKRHTKLDRNSFSKTIKRLDQDALDLRSLQILRGLIYNEECLLPDNWELKI NSSVQDILKCIKNVQNCLNKLNLSSRTQIHMVNSCDLVKREAITLQSAMLMNANKNVQESLLRYFKGAQEEVFFSAIKYQLQNAFTDLKDQKLMLSQKKSFGDIEKYTCHESDLRIDNLAHILYQQLAEYEIRYEDQNRSLAINRYAYTTTKESFTTRHMRQIYTPAKMKSEINSSSPLICCPRNSSKSNYDMRSTDKSDSLFKNNLQDEYELKSVVTKESNSSTDKTIENSAWIKGETLDLMRNDPHQNVKLILQLLSRMCVGQYQGLQNYLRIQPDNRSSVDVISLIVQFLGNIYANVRQSTIDLSIQAFDTIKETIMGNQENRSVVYRAKVVDYANFILRNDEISETCDPNNVLQMFLVIGRVIMALIEENGREETELAKEIQITLDIKAVFKIMTRCLDMMEDTKRKLIKNKIYDVGFTYFLILARLEDLCNGKLLKHFQISDQQMKAFKFFKKGSASVEILKGDQLQRIHFRLKHKEVLRESVKEKVKWEVDRTTPSNKIRSFISWSKLILPDMNFQRKIIQNPLLLFVTKQWNAMNYFLTLLSLVINIL
Sbjct:    1 MNDYLSYGDRICLYCEETNGFINSNNSSSHYNELRIFSKQDKFNPENVSDIQEIIFEVVIQNRYKLYKKYMKNYKDINNKSENLELKIQAEQAKATVISEENDNALENRRNLGKTVHYGDVIQLRHVYTRKYIHVNIAKTSSKDQNSMILNLQSHNLKSAQFKIVPRYKVKYEGEPVQFMDLVTFESLKAPSHYFHASDLYQIDNFFHGAALNLATEQSGFTLIKSASDTHIMEEDNFLRGGDYIQIIHKEIDGYIESEGIQGGMKKADIYLRIRKSDKFQTLTNSRLSSSANTFWQVEIEKVRLSTEIGQWSSNFRFRHATNRLYLSVKKDLSVSMTKNATNPNTVFRLYPQNIDKLIIPYGRYFRMEHVLTGTWIHANKEQVYVKPNQSKYDDAAEKCLGNLKYETNELRELFCVHQRLYDDAFVVFKVPTEIVESFNLLSGYFPLIKNLIVDRKKAVPFTASQSYRYKLALEEIRDSLYLDGKPHSLRQKHLRNLQIVDLLVELVLLPFHSKIDAAFTEKIYRASFEILHNYMKGSSIKNSLYFAKYINLFEPKMLENNDLGHKIIEMIAELLRNNQKVLECISFQEIFPFIDNLRINQNFRYLEYLETFCVCNGEPMTQNQIKIAVKWLSEDQRGVFLTDRGQNLNLESNVIYIKTKLDSNWMKLHEFLD-------ENNPLYHQDNKDYFLKQMDLLLALCYGRNQYCTNLIINKLNYISWEQCFAAINSPMIPPYMKTKYFEIIQTMFIDIGRNYAVIESPKFNFIFNQIQGDSSVAVECMFPTPSESVTIKIFKDLSEWIYNFLESTPRMISSNKDFNYLIRIVFITINKLIQYGYYDSPSLDRICKSLLKLLNGRNDLPFEYDSKKESLKIRKKLVTKYKNISRYEDSEETRAIVAAKLSGLEILDSILIYERVSVVAKLISRFKKCVQPDLKVQKKRLTGHTHLEACLSNGFDVAQQYKQSNRATKKMVSEIDNLFTTARFLDSEPWTNILIDLAHYQNEMMTQKSLLILHKLYSIKESSFQDTYATFISKTKQSQDLQELMCEYIPALRLLTKSLIGPPDLEKIAAMITEMINVCKIPKSDSFNPISQRIIVGYGILDIAMETIAQIYRSFDRSKMMYGASEVISLITNLLRHLAISNPSFQENLFNNLDTLLDLYEHSPPAELADLLRCGLFHNNRTFCGTLKSFQINKIVLMVADTARKNPLVGAAFIHLLESIVAVNNGEVPLKRNQLMVMKFVMKSFNQLVYILDSKSMSRVDLLTIHSASNDAFYFTKVIDLFIACCQGENQYVQSLCQTIMPLDELFDLLTHNDISIIYKRGLLKYFSKVYLSRTNISNQEGIIKNFIESKYCGEILDSIERTTLLTQIILDKTEHFNLLPILKKEFILKPPTEFQVSENIQMHLHYIIFGSSIFMASLCSAFSIMEISPAPELMKVIKSINHITMDIFSQMWKFQLHPSVFSVITESVLQIISYTDTSDLEAKTMALQHCKPQIMDFDPRKEIDNLYTEEIELNLKLQTFIFNCSQLIAGQNTVKAQIKANLRKQYVNLLDQNALPLNLEYQNHLKCFINNSYQKGEIRRYKLVDILIRQLEISGSVERNGKRHTKLDRNSFSKTIKRLDQDALDLRSLQILRGLIYNEECLLPDNWELKILNSSVQDILKCIKNVQNCLNKLNLSSRTQIHMVNSCDLVKREAITLQSAMLMNANKNVQESLLRYFKGAQEEVFFSAIKYQLQNAFTDLKDQKLMLSQKKSFGDIEKYTCHESDLRIDNLAHILYQQLAEYEIRYEDQNRSLAINRYAYTTTKESFTTRHMRQIYTPAKMKSEINSSSPLICCPRNSSKSNYDMRSTDKSDSLFKNNLQDEYELKSVVTKESNSSTDKTIENSAWIKGETLDLMRNDPHQNVKLILQLLSRMCVGQYQGLQNYLRIQPDNRSSVDVISLIVQFLGNIYANVRQSTIDLSIQAFDTIKETIMGNQENRSVVYRAKVVDYANFILRNDEISETCDPNNVLQMFLVIGRVIMALIEENGREETELAKEIQITLDIKAVFKIMTRCLDMMEDTKRKLIKNKIYDVGFTYFLILARLEDLCNGKLLKHFQISDQQMKAFKFFKKGSASVEILKGDQLQRIHFRLKHKEVLRESVKEKVKWEVDRTTPSNKIRSFISWSKLILPDMNFQRKIIQNPLLLFVTKQWNAMNYFLTLLSLVINIL 2207          

HSP 2 Score: 507.294 bits (1305), Expect = 1.459e-144
Identity = 308/316 (97.47%), Postives = 310/316 (98.10%), Query Frame = 3
Query: 7125 FFVFLYEISLLLSMSIGGIWIPYLYVFHLFNVIHNNQLLKGVIASVTKNGRXXXXXXXXXXXXXXXFSIFAFCFLRSTFSSENYLYADTLVQTFVSLVRFGIVGDLYQYTIPHKYYMKTVDTAFTEFSXXXXXXXXXXXXXXXXXXXXXXXXXVDTFSELRDLKYKTEKDMKETCFICSRAGHDFDQSSSSFEHHVVYEHNMWAYLFYFLHLKEIKINDYFHLDLYVANMLKRENYDFFPINCALSLTAEQEKYSRIDEISRNVKIIVSNRQNEEREKLRRTNLFKXXXXXXXXXXXXXXSGSYQDLNVDEINFDG 8072
            F  FLY   + L+MSIGGIWIPYLYVFHLFNVIHNNQLLKGVIASVTKNGRVLIWVMILMVIVMYIFSIFAFCFLRSTFSSENYLYADTLVQTFVSLVRFGIVGDLYQYTIPHKYYMKTVDTAFTEFSLILIFQLFFFIFITITGLNIIFGIIVDTFSELRDLKYKTEKDMKETCFICSRAGHDFDQSSSSFEHHVVYEHNMWAYLFYFLHLKEIKINDYFHLDLYVANMLKRENYDFFPINCALSLTAEQEKYSRIDEISRNVKIIVSNRQNEEREKLRRTNLFKQSQWQKQYQNSQVSSGSYQDLNVDEINFDG
Sbjct: 2319 FMRFLY-CCISLAMSIGGIWIPYLYVFHLFNVIHNNQLLKGVIASVTKNGRVLIWVMILMVIVMYIFSIFAFCFLRSTFSSENYLYADTLVQTFVSLVRFGIVGDLYQYTIPHKYYMKTVDTAFTEFSLILIFQLFFFIFITITGLNIIFGIIVDTFSELRDLKYKTEKDMKETCFICSRAGHDFDQSSSSFEHHVVYEHNMWAYLFYFLHLKEIKINDYFHLDLYVANMLKRENYDFFPINCALSLTAEQEKYSRIDEISRNVKIIVSNRQNEEREKLRRTNLFKQSQWQKQYQNSQVSSGSYQDLNVDEINFDG 2633          

HSP 3 Score: 253.832 bits (647), Expect = 5.547e-67
Identity = 120/127 (94.49%), Postives = 122/127 (96.06%), Query Frame = 1
Query: 6805 LLIGVKAPDKGYINLTGPISPRHSDFDNYTIIWKPQYVIFREVVMGLGVSHAVIAFLILITYLITDRPTLRTIRSYASRIKQRMVSFYKKEDENDSEKMVDGTNQLVSLFSFMRFLYCCPCQSVESG 7185
            LLIGVKAPDKGYINLTGPISPRHSDFDNYTIIWKPQYVIFREVVMGLGVSHAVIAFLILITYLITDRPTLRTIRSYASRIKQRMVSFYKKEDENDSEKMVDGTNQLVSLFSFMRFLYCC   ++  G
Sbjct: 2208 LLIGVKAPDKGYINLTGPISPRHSDFDNYTIIWKPQYVIFREVVMGLGVSHAVIAFLILITYLITDRPTLRTIRSYASRIKQRMVSFYKKEDENDSEKMVDGTNQLVSLFSFMRFLYCCISLAMSIG 2334          
BLAST of Inositol 1,4,5-trisphosphate receptor type 3 vs. Planmine SMEST
Match: SMESG000070557.1 (SMESG000070557.1)

HSP 1 Score: 4459.83 bits (11566), Expect = 0.000e+0
Identity = 2204/2214 (99.55%), Postives = 2204/2214 (99.55%), Query Frame = 2
Query:  164 MNDYLSYGDRICLYCEETNGFINSNNSSSHYNELRIFSKQDKFNPENVSDIQEIIFEVVIQNRXXXXXXXXXXXXDINNKSENLELKIQAEQAKATVISEENDNALENRRNLGKTVHYGDVIQLRHVYTRKYIHVNIAKTSSKDQNSMILNLQSHNLKSAQFKIVPRYKVKYEGEPVQFMDLVTFESLKAPSHYFHASDLYQIDNFFHGAALNLATEQSGFTLIKSASDTHIMEEDNFLRGGDYIQIIHKEIDGYIESEGIQGGMKKADIYLRIRKSDKFQTLTNSRLSSSANTFWQVEIEKVRLSTEIGQWSSNFRFRHATNRLYLSVKKDLSVSMTKNATNPNTVFRLYPQNIDKLIIPYGRYFRMEHVLTGTWIHANKEQVYVKPNQSKYDDAAEKCLGNLKYETNELRELFCVHQRLYDDAFVVFKVPTEIVESFNLLSGYFPLIKNLIVDRKKAVPFTASQSYRYKLALEEIRDSLYLDGKPHSLRQKHLRNLQIVDLLVELVLLPFHSKIDAAFTEKIYRASFEILHNYMKGSSIKNSLYFAKYINLFEPKMLENNDLGHKIIEMIAELLRNNQKVLECISFQEIFPFIDNLRINQNFRYLEYLETFCVCNGEPMTQNQIKIAVKWLSEDQRGVFLTDRGQNLNLESNVIYIKTKLDSNWMKLHEFLDITAQIDQENNPLYHQDNKDYFLKQMDLLLALCYGRNQYCTNLIINKLNYISWEQCFAAINSPMIPPYMKTKYFEIIQTMFIDIGRNYAVIESPKFNFIFNQIQGDSSVAVECMFPTPSESVTIKIFKDLSEWIYNFLESTPRMISSNKDFNYLIRIVFITINKLIQYGYYDSPSLDRICKSLLKLLNGRNDLPFEYDSKKESLKIRKKLVTKYKNISRYEDSEETRAIVAAKLSGLEILDSILIYERVSVVAKLISRFKKCVQPDLKVQKKRLTGHTHLEACLSNGFDVAQQYKQSNRATKKMVSEIDNLFTTARFLDSEPWTNILIDLAHYQNEMMTQKSLLILHKLYSIKESSFQDTYATFISKTKQSQDLQELMCEYIPALRLHTKSLIGPPDLEKIAAMITEMINVCKIPKSDSFNPISQRIIVGYGILDIAMETIAQIYRSFDRSKMMYGASEVISLITNLLRHLAISNPSFQEXXXXXXXXXXXXYEHSPPAELADLLRCGLFHNNRTFCGTLKSFQINKIVLMVADTARKNPLVGAAFIHLLESIVAVNNGEVPLKRNQLMVMKFVMKSFNQLVYILDSKSMSRVDLLTIHSASNDAFYFTKVIDLFIACCQGENQYVQSLCQTIMPLDELFDLLTHNDISIIYKRGLLKYFSKVYLSRTNISNQEGIIKNFIESKYCGEILDSIERTTLLTQIILDKTEHFNLLPILKKEFILKPPTEFQVSENIQMHLHYIIFGSSIFMASLCSAFSIMEISPAPELMKVIKSINHITMDIFSQMWKFQLHPSVFSVITESVLQIISYTDTSDLEAKTMALQHCKPQIMDFDPRKEIDNLYTEEIELNLKLQTFIFNCSQLIAGQNTVKAQIKANLRKQYVNLLDQNALPLNLEYQNHLKCFINNSYQKGEIRRYKLVDILIRQLEISGSVERNGKRHTKLDRNSFSKTIKRLDQDALDLRSLQILRGLIYNEECLLPDNWELKIFNSSVQDILKCIKNVQNCLNKLNLSSRTQIHMVNSCDLVKREAITLQSAMLMNANKNVQESLLRYFKGAQEEVFFSAIKYQLQNAFTDLKDQKLMLSQKKSFGDIEKYTCHESDLRIDNLAHILYQQLAEYEIRYEDQNRSLAINRYAYTTTKESFTTRHMRQIYTPAKMKSEINSSSPLICCPRNSSKSNYDMRSTDKSDSLFKNNLQDEYELKSVVTKESNSSTDKTIENSAWIKGETLDLMRNDPHQNVKLILQLLSRMCVGQYQGLQNYLRIQPDNRSSVDVISLIVQFLGNIYANVRQSTIDLSIQAFDTIKETIMGNQENRSVVYRAKVVDYANFILRNDEISETCDPNNVLQMFLVIGRVIMALIEENGREETELAKEIQITLDIKAVFKIMTRCLDMMEDTKRKLIKNKIYDVGFTYFLILARLEDLCNGKLLKHFQISDQQMKAXXXXXXGSASVEILKGDQLQRIHFRLKHKEVLRESVKEKVKWEVDRTTPSNKIRSFISWSKLILPDMNFQRKIIQNPLLLFVTKQWNAMNYFLTLLSLVINIL 6805
            MNDYLSYGDRICLYCEETNGFINSNNSSSHYNELRIFSKQDKFNPENVSDIQEIIFEVVIQNRYKLYKKYMKNYKDINNKSENLELKIQAEQAKATVISEENDNALENRRNLGKTVHYGDVIQLRHVYTRKYIHVNIAKTSSKDQNSMILNLQSHNLKSAQFKIVPRYKVKYEGEPVQFMDLVTFESLKAPSHYFHASDLYQIDNFFHGAALNLATEQSGFTLIKSASDTHIMEEDNFLRGGDYIQIIHKEIDGYIESEGIQGGMKKADIYLRIRKSDKFQTLTNSRLSSSANTFWQVEIEKVRLSTEIGQWSSNFRFRHATNRLYLSVKKDLSVSMTKNATNPNTVFRLYPQNIDKLIIPYGRYFRMEHVLTGTWIHANKEQVYVKPNQSKYDDAAEKCLGNLKYETNELRELFCVHQRLYDDAFVVFKVPTEIVESFNLLSGYFPLIKNLIVDRKKAVPFTASQSYRYKLALEEIRDSLYLDGKPHSLRQKHLRNLQIVDLLVELVLLPFHSKIDAAFTEKIYRASFEILHNYMKGSSIKNSLYFAKYINLFEPKMLENNDLGHKIIEMIAELLRNNQKVLECISFQEIFPFIDNLRINQNFRYLEYLETFCVCNGEPMTQNQIKIAVKWLSEDQRGVFLTDRGQNLNLESNVIYIKTKLDSNWMKLHEFLDITAQIDQENNPLYHQDNKDYFLKQMDLLLALCYGRNQYCTNLIINKLNYISWEQCFAAINSPMIPPYMKTKYFEIIQTMFIDIGRNYAVIESPKFNFIFNQIQGDSSVAVECMFPTPSESVTIKIFKDLSEWIYNFLESTPRMISSNKDFNYLIRIVFITINKLIQYGYYDSPSLDRICKSLLKLLNGRNDLPFEYDSKKESLKIRKKLVTKYKNISRYEDSEETRAIVAAKLSGLEILDSILIYERVSVVAKLISRFKKCVQPDLKVQKKRLTGHTHLEACLSNGFDVAQQYKQSNRATKKMVSEIDNLFTTARFLDSEPWTNILIDLAHYQNEMMTQKSLLILHKLYSIKESSFQDTYATFISKTKQSQDLQELMCEYIPALRL TKSLIGPPDLEKIAAMITEMINVCKIPKSDSFNPISQRIIVGYGILDIAMETIAQIYRSFDRSKMMYGASEVISLITNLLRHLAISNPSFQENLFNNLDTLLDLYEHSPPAELADLLRCGLFHNNRTFCGTLKSFQINKIVLMVADTARKNPLVGAAFIHLLESIVAVNNGEVPLKRNQLMVMKFVMKSFNQLVYILDSKSMSRVDLLTIHSASNDAFYFTKVIDLFIACCQGENQYVQSLCQTIMPLDELFDLLTHNDISIIYKRGLLKYFSKVYLSRTNISNQEGIIKNFIESKYCGEILDSIERTTLLTQIILDKTEHFNLLPILKKEFILKPPTEFQVSENIQMHLHYIIFGSSIFMASLCSAFSIMEISPAPELMKVIKSINHITMDIFSQMWKFQLHPSVFSVITESVLQIISYTDTSDLEAKTMALQHCKPQIMDFDPRKEIDNLYTEEIELNLKLQTFIFNCSQLIAGQNTVKAQIKANLRKQYVNLLDQNALPLNLEYQNHLKCFINNSYQKGEIRRYKLVDILIRQLEISGSVERNGKRHTKLDRNSFSKTIKRLDQDALDLRSLQILRGLIYNEECLLPDNWELKI NSSVQDILKCIKNVQNCLNKLNLSSRTQIHMVNSCDLVKREAITLQSAMLMNANKNVQESLLRYFKGAQEEVFFSAIKYQLQNAFTDLKDQKLMLSQKKSFGDIEKYTCHESDLRIDNLAHILYQQLAEYEIRYEDQNRSLAIN        ESFTTRHMRQIYTPAKMKSEINSSSPLICCPRNSSKSNYDMRSTDKSDSLFKNNLQDEYELKSVVTKESNSSTDKTIENSAWIKGETLDLMRNDPHQNVKLILQLLSRMCVGQYQGLQNYLRIQPDNRSSVDVISLIVQFLGNIYANVRQSTIDLSIQAFDTIKETIMGNQENRSVVYRAKVVDYANFILRNDEISETCDPNNVLQMFLVIGRVIMALIEENGREETELAKEIQITLDIKAVFKIMTRCLDMMEDTKRKLIKNKIYDVGFTYFLILARLEDLCNGKLLKHFQISDQQMKAFKFFKKGSASVEILKGDQLQRIHFRLKHKEVLRESVKEKVKWEVDRTTPSNKIRSFISWSKLILPDMNFQRKIIQNPLLLFVTKQWNAMNYFLTLLSLVINIL
Sbjct:    1 MNDYLSYGDRICLYCEETNGFINSNNSSSHYNELRIFSKQDKFNPENVSDIQEIIFEVVIQNRYKLYKKYMKNYKDINNKSENLELKIQAEQAKATVISEENDNALENRRNLGKTVHYGDVIQLRHVYTRKYIHVNIAKTSSKDQNSMILNLQSHNLKSAQFKIVPRYKVKYEGEPVQFMDLVTFESLKAPSHYFHASDLYQIDNFFHGAALNLATEQSGFTLIKSASDTHIMEEDNFLRGGDYIQIIHKEIDGYIESEGIQGGMKKADIYLRIRKSDKFQTLTNSRLSSSANTFWQVEIEKVRLSTEIGQWSSNFRFRHATNRLYLSVKKDLSVSMTKNATNPNTVFRLYPQNIDKLIIPYGRYFRMEHVLTGTWIHANKEQVYVKPNQSKYDDAAEKCLGNLKYETNELRELFCVHQRLYDDAFVVFKVPTEIVESFNLLSGYFPLIKNLIVDRKKAVPFTASQSYRYKLALEEIRDSLYLDGKPHSLRQKHLRNLQIVDLLVELVLLPFHSKIDAAFTEKIYRASFEILHNYMKGSSIKNSLYFAKYINLFEPKMLENNDLGHKIIEMIAELLRNNQKVLECISFQEIFPFIDNLRINQNFRYLEYLETFCVCNGEPMTQNQIKIAVKWLSEDQRGVFLTDRGQNLNLESNVIYIKTKLDSNWMKLHEFLDITAQIDQENNPLYHQDNKDYFLKQMDLLLALCYGRNQYCTNLIINKLNYISWEQCFAAINSPMIPPYMKTKYFEIIQTMFIDIGRNYAVIESPKFNFIFNQIQGDSSVAVECMFPTPSESVTIKIFKDLSEWIYNFLESTPRMISSNKDFNYLIRIVFITINKLIQYGYYDSPSLDRICKSLLKLLNGRNDLPFEYDSKKESLKIRKKLVTKYKNISRYEDSEETRAIVAAKLSGLEILDSILIYERVSVVAKLISRFKKCVQPDLKVQKKRLTGHTHLEACLSNGFDVAQQYKQSNRATKKMVSEIDNLFTTARFLDSEPWTNILIDLAHYQNEMMTQKSLLILHKLYSIKESSFQDTYATFISKTKQSQDLQELMCEYIPALRLLTKSLIGPPDLEKIAAMITEMINVCKIPKSDSFNPISQRIIVGYGILDIAMETIAQIYRSFDRSKMMYGASEVISLITNLLRHLAISNPSFQENLFNNLDTLLDLYEHSPPAELADLLRCGLFHNNRTFCGTLKSFQINKIVLMVADTARKNPLVGAAFIHLLESIVAVNNGEVPLKRNQLMVMKFVMKSFNQLVYILDSKSMSRVDLLTIHSASNDAFYFTKVIDLFIACCQGENQYVQSLCQTIMPLDELFDLLTHNDISIIYKRGLLKYFSKVYLSRTNISNQEGIIKNFIESKYCGEILDSIERTTLLTQIILDKTEHFNLLPILKKEFILKPPTEFQVSENIQMHLHYIIFGSSIFMASLCSAFSIMEISPAPELMKVIKSINHITMDIFSQMWKFQLHPSVFSVITESVLQIISYTDTSDLEAKTMALQHCKPQIMDFDPRKEIDNLYTEEIELNLKLQTFIFNCSQLIAGQNTVKAQIKANLRKQYVNLLDQNALPLNLEYQNHLKCFINNSYQKGEIRRYKLVDILIRQLEISGSVERNGKRHTKLDRNSFSKTIKRLDQDALDLRSLQILRGLIYNEECLLPDNWELKILNSSVQDILKCIKNVQNCLNKLNLSSRTQIHMVNSCDLVKREAITLQSAMLMNANKNVQESLLRYFKGAQEEVFFSAIKYQLQNAFTDLKDQKLMLSQKKSFGDIEKYTCHESDLRIDNLAHILYQQLAEYEIRYEDQNRSLAIN--------ESFTTRHMRQIYTPAKMKSEINSSSPLICCPRNSSKSNYDMRSTDKSDSLFKNNLQDEYELKSVVTKESNSSTDKTIENSAWIKGETLDLMRNDPHQNVKLILQLLSRMCVGQYQGLQNYLRIQPDNRSSVDVISLIVQFLGNIYANVRQSTIDLSIQAFDTIKETIMGNQENRSVVYRAKVVDYANFILRNDEISETCDPNNVLQMFLVIGRVIMALIEENGREETELAKEIQITLDIKAVFKIMTRCLDMMEDTKRKLIKNKIYDVGFTYFLILARLEDLCNGKLLKHFQISDQQMKAFKFFKKGSASVEILKGDQLQRIHFRLKHKEVLRESVKEKVKWEVDRTTPSNKIRSFISWSKLILPDMNFQRKIIQNPLLLFVTKQWNAMNYFLTLLSLVINIL 2206          

HSP 2 Score: 507.679 bits (1306), Expect = 1.104e-144
Identity = 308/316 (97.47%), Postives = 310/316 (98.10%), Query Frame = 3
Query: 7125 FFVFLYEISLLLSMSIGGIWIPYLYVFHLFNVIHNNQLLKGVIASVTKNGRXXXXXXXXXXXXXXXFSIFAFCFLRSTFSSENYLYADTLVQTFVSLVRFGIVGDLYQYTIPHKYYMKTVDTAFTEFSXXXXXXXXXXXXXXXXXXXXXXXXXVDTFSELRDLKYKTEKDMKETCFICSRAGHDFDQSSSSFEHHVVYEHNMWAYLFYFLHLKEIKINDYFHLDLYVANMLKRENYDFFPINCALSLTAEQEKYSRIDEISRNVKIIVSNRQNEEREKLRRTNLFKXXXXXXXXXXXXXXSGSYQDLNVDEINFDG 8072
            F  FLY   + L+MSIGGIWIPYLYVFHLFNVIHNNQLLKGVIASVTKNGRVLIWVMILMVIVMYIFSIFAFCFLRSTFSSENYLYADTLVQTFVSLVRFGIVGDLYQYTIPHKYYMKTVDTAFTEFSLILIFQLFFFIFITITGLNIIFGIIVDTFSELRDLKYKTEKDMKETCFICSRAGHDFDQSSSSFEHHVVYEHNMWAYLFYFLHLKEIKINDYFHLDLYVANMLKRENYDFFPINCALSLTAEQEKYSRIDEISRNVKIIVSNRQNEEREKLRRTNLFKQSQWQKQYQNSQVSSGSYQDLNVDEINFDG
Sbjct: 2318 FMRFLY-CCISLAMSIGGIWIPYLYVFHLFNVIHNNQLLKGVIASVTKNGRVLIWVMILMVIVMYIFSIFAFCFLRSTFSSENYLYADTLVQTFVSLVRFGIVGDLYQYTIPHKYYMKTVDTAFTEFSLILIFQLFFFIFITITGLNIIFGIIVDTFSELRDLKYKTEKDMKETCFICSRAGHDFDQSSSSFEHHVVYEHNMWAYLFYFLHLKEIKINDYFHLDLYVANMLKRENYDFFPINCALSLTAEQEKYSRIDEISRNVKIIVSNRQNEEREKLRRTNLFKQSQWQKQYQNSQVSSGSYQDLNVDEINFDG 2632          

HSP 3 Score: 253.832 bits (647), Expect = 5.784e-67
Identity = 120/127 (94.49%), Postives = 122/127 (96.06%), Query Frame = 1
Query: 6805 LLIGVKAPDKGYINLTGPISPRHSDFDNYTIIWKPQYVIFREVVMGLGVSHAVIAFLILITYLITDRPTLRTIRSYASRIKQRMVSFYKKEDENDSEKMVDGTNQLVSLFSFMRFLYCCPCQSVESG 7185
            LLIGVKAPDKGYINLTGPISPRHSDFDNYTIIWKPQYVIFREVVMGLGVSHAVIAFLILITYLITDRPTLRTIRSYASRIKQRMVSFYKKEDENDSEKMVDGTNQLVSLFSFMRFLYCC   ++  G
Sbjct: 2207 LLIGVKAPDKGYINLTGPISPRHSDFDNYTIIWKPQYVIFREVVMGLGVSHAVIAFLILITYLITDRPTLRTIRSYASRIKQRMVSFYKKEDENDSEKMVDGTNQLVSLFSFMRFLYCCISLAMSIG 2333          
BLAST of Inositol 1,4,5-trisphosphate receptor type 3 vs. Planmine SMEST
Match: SMESG000070557.1 (SMESG000070557.1)

HSP 1 Score: 4439.03 bits (11512), Expect = 0.000e+0
Identity = 2197/2214 (99.23%), Postives = 2197/2214 (99.23%), Query Frame = 2
Query:  164 MNDYLSYGDRICLYCEETNGFINSNNSSSHYNELRIFSKQDKFNPENVSDIQEIIFEVVIQNRXXXXXXXXXXXXDINNKSENLELKIQAEQAKATVISEENDNALENRRNLGKTVHYGDVIQLRHVYTRKYIHVNIAKTSSKDQNSMILNLQSHNLKSAQFKIVPRYKVKYEGEPVQFMDLVTFESLKAPSHYFHASDLYQIDNFFHGAALNLATEQSGFTLIKSASDTHIMEEDNFLRGGDYIQIIHKEIDGYIESEGIQGGMKKADIYLRIRKSDKFQTLTNSRLSSSANTFWQVEIEKVRLSTEIGQWSSNFRFRHATNRLYLSVKKDLSVSMTKNATNPNTVFRLYPQNIDKLIIPYGRYFRMEHVLTGTWIHANKEQVYVKPNQSKYDDAAEKCLGNLKYETNELRELFCVHQRLYDDAFVVFKVPTEIVESFNLLSGYFPLIKNLIVDRKKAVPFTASQSYRYKLALEEIRDSLYLDGKPHSLRQKHLRNLQIVDLLVELVLLPFHSKIDAAFTEKIYRASFEILHNYMKGSSIKNSLYFAKYINLFEPKMLENNDLGHKIIEMIAELLRNNQKVLECISFQEIFPFIDNLRINQNFRYLEYLETFCVCNGEPMTQNQIKIAVKWLSEDQRGVFLTDRGQNLNLESNVIYIKTKLDSNWMKLHEFLDITAQIDQENNPLYHQDNKDYFLKQMDLLLALCYGRNQYCTNLIINKLNYISWEQCFAAINSPMIPPYMKTKYFEIIQTMFIDIGRNYAVIESPKFNFIFNQIQGDSSVAVECMFPTPSESVTIKIFKDLSEWIYNFLESTPRMISSNKDFNYLIRIVFITINKLIQYGYYDSPSLDRICKSLLKLLNGRNDLPFEYDSKKESLKIRKKLVTKYKNISRYEDSEETRAIVAAKLSGLEILDSILIYERVSVVAKLISRFKKCVQPDLKVQKKRLTGHTHLEACLSNGFDVAQQYKQSNRATKKMVSEIDNLFTTARFLDSEPWTNILIDLAHYQNEMMTQKSLLILHKLYSIKESSFQDTYATFISKTKQSQDLQELMCEYIPALRLHTKSLIGPPDLEKIAAMITEMINVCKIPKSDSFNPISQRIIVGYGILDIAMETIAQIYRSFDRSKMMYGASEVISLITNLLRHLAISNPSFQEXXXXXXXXXXXXYEHSPPAELADLLRCGLFHNNRTFCGTLKSFQINKIVLMVADTARKNPLVGAAFIHLLESIVAVNNGEVPLKRNQLMVMKFVMKSFNQLVYILDSKSMSRVDLLTIHSASNDAFYFTKVIDLFIACCQGENQYVQSLCQTIMPLDELFDLLTHNDISIIYKRGLLKYFSKVYLSRTNISNQEGIIKNFIESKYCGEILDSIERTTLLTQIILDKTEHFNLLPILKKEFILKPPTEFQVSENIQMHLHYIIFGSSIFMASLCSAFSIMEISPAPELMKVIKSINHITMDIFSQMWKFQLHPSVFSVITESVLQIISYTDTSDLEAKTMALQHCKPQIMDFDPRKEIDNLYTEEIELNLKLQTFIFNCSQLIAGQNTVKAQIKANLRKQYVNLLDQNALPLNLEYQNHLKCFINNSYQKGEIRRYKLVDILIRQLEISGSVERNGKRHTKLDRNSFSKTIKRLDQDALDLRSLQILRGLIYNEECLLPDNWELKIFNSSVQDILKCIKNVQNCLNKLNLSSRTQIHMVNSCDLVKREAITLQSAMLMNANKNVQESLLRYFKGAQEEVFFSAIKYQLQNAFTDLKDQKLMLSQKKSFGDIEKYTCHESDLRIDNLAHILYQQLAEYEIRYEDQNRSLAINRYAYTTTKESFTTRHMRQIYTPAKMKSEINSSSPLICCPRNSSKSNYDMRSTDKSDSLFKNNLQDEYELKSVVTKESNSSTDKTIENSAWIKGETLDLMRNDPHQNVKLILQLLSRMCVGQYQGLQNYLRIQPDNRSSVDVISLIVQFLGNIYANVRQSTIDLSIQAFDTIKETIMGNQENRSVVYRAKVVDYANFILRNDEISETCDPNNVLQMFLVIGRVIMALIEENGREETELAKEIQITLDIKAVFKIMTRCLDMMEDTKRKLIKNKIYDVGFTYFLILARLEDLCNGKLLKHFQISDQQMKAXXXXXXGSASVEILKGDQLQRIHFRLKHKEVLRESVKEKVKWEVDRTTPSNKIRSFISWSKLILPDMNFQRKIIQNPLLLFVTKQWNAMNYFLTLLSLVINIL 6805
            MNDYLSYGDRICLYCEETNGFINSNNSSSHYNELRIFSKQDKFNPENVSDIQEIIFEVVIQNRYKLYKKYMKNYKDINNKSENLELKIQAEQAKATVISEENDNALENRRNLGKTVHYGDVIQLRHVYTRKYIHVNIAKTSSKDQNSMILNLQSHNLKSAQFKIVPRYKVKYEGEPVQFMDLVTFESLKAPSHYFHASDLYQIDNFFHGAALNLATEQSGFTLIKSASDTHIMEEDNFLRGGDYIQIIHKEIDGYIESEGIQGGMKKADIYLRIRKSDKFQTLTNSRLSSSANTFWQVEIEKVRLSTEIGQWSSNFRFRHATNRLYLSVKKDLSVSMTKNATNPNTVFRLYPQNIDKLIIPYGRYFRMEHVLTGTWIHANKEQVYVKPNQSKYDDAAEKCLGNLKYETNELRELFCVHQRLYDDAFVVFKVPTEIVESFNLLSGYFPLIKNLIVDRKKAVPFTASQSYRYKLALEEIRDSLYLDGKPHSLRQKHLRNLQIVDLLVELVLLPFHSKIDAAFTEKIYRASFEILHNYMKGSSIKNSLYFAKYINLFEPKMLENNDLGHKIIEMIAELLRNNQKVLECISFQEIFPFIDNLRINQNFRYLEYLETFCVCNGEPMTQNQIKIAVKWLSEDQRGVFLTDRGQNLNLESNVIYIKTKLDSNWMKLHEFLD       ENNPLYHQDNKDYFLKQMDLLLALCYGRNQYCTNLIINKLNYISWEQCFAAINSPMIPPYMKTKYFEIIQTMFIDIGRNYAVIESPKFNFIFNQIQGDSSVAVECMFPTPSESVTIKIFKDLSEWIYNFLESTPRMISSNKDFNYLIRIVFITINKLIQYGYYDSPSLDRICKSLLKLLNGRNDLPFEYDSKKESLKIRKKLVTKYKNISRYEDSEETRAIVAAKLSGLEILDSILIYERVSVVAKLISRFKKCVQPDLKVQKKRLTGHTHLEACLSNGFDVAQQYKQSNRATKKMVSEIDNLFTTARFLDSEPWTNILIDLAHYQNEMMTQKSLLILHKLYSIKESSFQDTYATFISKTKQSQDLQELMCEYIPALRL TKSLIGPPDLEKIAAMITEMINVCKIPKSDSFNPISQRIIVGYGILDIAMETIAQIYRSFDRSKMMYGASEVISLITNLLRHLAISNPSFQENLFNNLDTLLDLYEHSPPAELADLLRCGLFHNNRTFCGTLKSFQINKIVLMVADTARKNPLVGAAFIHLLESIVAVNNGEVPLKRNQLMVMKFVMKSFNQLVYILDSKSMSRVDLLTIHSASNDAFYFTKVIDLFIACCQGENQYVQSLCQTIMPLDELFDLLTHNDISIIYKRGLLKYFSKVYLSRTNISNQEGIIKNFIESKYCGEILDSIERTTLLTQIILDKTEHFNLLPILKKEFILKPPTEFQVSENIQMHLHYIIFGSSIFMASLCSAFSIMEISPAPELMKVIKSINHITMDIFSQMWKFQLHPSVFSVITESVLQIISYTDTSDLEAKTMALQHCKPQIMDFDPRKEIDNLYTEEIELNLKLQTFIFNCSQLIAGQNTVKAQIKANLRKQYVNLLDQNALPLNLEYQNHLKCFINNSYQKGEIRRYKLVDILIRQLEISGSVERNGKRHTKLDRNSFSKTIKRLDQDALDLRSLQILRGLIYNEECLLPDNWELKI NSSVQDILKCIKNVQNCLNKLNLSSRTQIHMVNSCDLVKREAITLQSAMLMNANKNVQESLLRYFKGAQEEVFFSAIKYQLQNAFTDLKDQKLMLSQKKSFGDIEKYTCHESDLRIDNLAHILYQQLAEYEIRYEDQNRSLAIN        ESFTTRHMRQIYTPAKMKSEINSSSPLICCPRNSSKSNYDMRSTDKSDSLFKNNLQDEYELKSVVTKESNSSTDKTIENSAWIKGETLDLMRNDPHQNVKLILQLLSRMCVGQYQGLQNYLRIQPDNRSSVDVISLIVQFLGNIYANVRQSTIDLSIQAFDTIKETIMGNQENRSVVYRAKVVDYANFILRNDEISETCDPNNVLQMFLVIGRVIMALIEENGREETELAKEIQITLDIKAVFKIMTRCLDMMEDTKRKLIKNKIYDVGFTYFLILARLEDLCNGKLLKHFQISDQQMKAFKFFKKGSASVEILKGDQLQRIHFRLKHKEVLRESVKEKVKWEVDRTTPSNKIRSFISWSKLILPDMNFQRKIIQNPLLLFVTKQWNAMNYFLTLLSLVINIL
Sbjct:    1 MNDYLSYGDRICLYCEETNGFINSNNSSSHYNELRIFSKQDKFNPENVSDIQEIIFEVVIQNRYKLYKKYMKNYKDINNKSENLELKIQAEQAKATVISEENDNALENRRNLGKTVHYGDVIQLRHVYTRKYIHVNIAKTSSKDQNSMILNLQSHNLKSAQFKIVPRYKVKYEGEPVQFMDLVTFESLKAPSHYFHASDLYQIDNFFHGAALNLATEQSGFTLIKSASDTHIMEEDNFLRGGDYIQIIHKEIDGYIESEGIQGGMKKADIYLRIRKSDKFQTLTNSRLSSSANTFWQVEIEKVRLSTEIGQWSSNFRFRHATNRLYLSVKKDLSVSMTKNATNPNTVFRLYPQNIDKLIIPYGRYFRMEHVLTGTWIHANKEQVYVKPNQSKYDDAAEKCLGNLKYETNELRELFCVHQRLYDDAFVVFKVPTEIVESFNLLSGYFPLIKNLIVDRKKAVPFTASQSYRYKLALEEIRDSLYLDGKPHSLRQKHLRNLQIVDLLVELVLLPFHSKIDAAFTEKIYRASFEILHNYMKGSSIKNSLYFAKYINLFEPKMLENNDLGHKIIEMIAELLRNNQKVLECISFQEIFPFIDNLRINQNFRYLEYLETFCVCNGEPMTQNQIKIAVKWLSEDQRGVFLTDRGQNLNLESNVIYIKTKLDSNWMKLHEFLD-------ENNPLYHQDNKDYFLKQMDLLLALCYGRNQYCTNLIINKLNYISWEQCFAAINSPMIPPYMKTKYFEIIQTMFIDIGRNYAVIESPKFNFIFNQIQGDSSVAVECMFPTPSESVTIKIFKDLSEWIYNFLESTPRMISSNKDFNYLIRIVFITINKLIQYGYYDSPSLDRICKSLLKLLNGRNDLPFEYDSKKESLKIRKKLVTKYKNISRYEDSEETRAIVAAKLSGLEILDSILIYERVSVVAKLISRFKKCVQPDLKVQKKRLTGHTHLEACLSNGFDVAQQYKQSNRATKKMVSEIDNLFTTARFLDSEPWTNILIDLAHYQNEMMTQKSLLILHKLYSIKESSFQDTYATFISKTKQSQDLQELMCEYIPALRLLTKSLIGPPDLEKIAAMITEMINVCKIPKSDSFNPISQRIIVGYGILDIAMETIAQIYRSFDRSKMMYGASEVISLITNLLRHLAISNPSFQENLFNNLDTLLDLYEHSPPAELADLLRCGLFHNNRTFCGTLKSFQINKIVLMVADTARKNPLVGAAFIHLLESIVAVNNGEVPLKRNQLMVMKFVMKSFNQLVYILDSKSMSRVDLLTIHSASNDAFYFTKVIDLFIACCQGENQYVQSLCQTIMPLDELFDLLTHNDISIIYKRGLLKYFSKVYLSRTNISNQEGIIKNFIESKYCGEILDSIERTTLLTQIILDKTEHFNLLPILKKEFILKPPTEFQVSENIQMHLHYIIFGSSIFMASLCSAFSIMEISPAPELMKVIKSINHITMDIFSQMWKFQLHPSVFSVITESVLQIISYTDTSDLEAKTMALQHCKPQIMDFDPRKEIDNLYTEEIELNLKLQTFIFNCSQLIAGQNTVKAQIKANLRKQYVNLLDQNALPLNLEYQNHLKCFINNSYQKGEIRRYKLVDILIRQLEISGSVERNGKRHTKLDRNSFSKTIKRLDQDALDLRSLQILRGLIYNEECLLPDNWELKILNSSVQDILKCIKNVQNCLNKLNLSSRTQIHMVNSCDLVKREAITLQSAMLMNANKNVQESLLRYFKGAQEEVFFSAIKYQLQNAFTDLKDQKLMLSQKKSFGDIEKYTCHESDLRIDNLAHILYQQLAEYEIRYEDQNRSLAIN--------ESFTTRHMRQIYTPAKMKSEINSSSPLICCPRNSSKSNYDMRSTDKSDSLFKNNLQDEYELKSVVTKESNSSTDKTIENSAWIKGETLDLMRNDPHQNVKLILQLLSRMCVGQYQGLQNYLRIQPDNRSSVDVISLIVQFLGNIYANVRQSTIDLSIQAFDTIKETIMGNQENRSVVYRAKVVDYANFILRNDEISETCDPNNVLQMFLVIGRVIMALIEENGREETELAKEIQITLDIKAVFKIMTRCLDMMEDTKRKLIKNKIYDVGFTYFLILARLEDLCNGKLLKHFQISDQQMKAFKFFKKGSASVEILKGDQLQRIHFRLKHKEVLRESVKEKVKWEVDRTTPSNKIRSFISWSKLILPDMNFQRKIIQNPLLLFVTKQWNAMNYFLTLLSLVINIL 2199          

HSP 2 Score: 507.679 bits (1306), Expect = 1.172e-144
Identity = 308/316 (97.47%), Postives = 310/316 (98.10%), Query Frame = 3
Query: 7125 FFVFLYEISLLLSMSIGGIWIPYLYVFHLFNVIHNNQLLKGVIASVTKNGRXXXXXXXXXXXXXXXFSIFAFCFLRSTFSSENYLYADTLVQTFVSLVRFGIVGDLYQYTIPHKYYMKTVDTAFTEFSXXXXXXXXXXXXXXXXXXXXXXXXXVDTFSELRDLKYKTEKDMKETCFICSRAGHDFDQSSSSFEHHVVYEHNMWAYLFYFLHLKEIKINDYFHLDLYVANMLKRENYDFFPINCALSLTAEQEKYSRIDEISRNVKIIVSNRQNEEREKLRRTNLFKXXXXXXXXXXXXXXSGSYQDLNVDEINFDG 8072
            F  FLY   + L+MSIGGIWIPYLYVFHLFNVIHNNQLLKGVIASVTKNGRVLIWVMILMVIVMYIFSIFAFCFLRSTFSSENYLYADTLVQTFVSLVRFGIVGDLYQYTIPHKYYMKTVDTAFTEFSLILIFQLFFFIFITITGLNIIFGIIVDTFSELRDLKYKTEKDMKETCFICSRAGHDFDQSSSSFEHHVVYEHNMWAYLFYFLHLKEIKINDYFHLDLYVANMLKRENYDFFPINCALSLTAEQEKYSRIDEISRNVKIIVSNRQNEEREKLRRTNLFKQSQWQKQYQNSQVSSGSYQDLNVDEINFDG
Sbjct: 2311 FMRFLY-CCISLAMSIGGIWIPYLYVFHLFNVIHNNQLLKGVIASVTKNGRVLIWVMILMVIVMYIFSIFAFCFLRSTFSSENYLYADTLVQTFVSLVRFGIVGDLYQYTIPHKYYMKTVDTAFTEFSLILIFQLFFFIFITITGLNIIFGIIVDTFSELRDLKYKTEKDMKETCFICSRAGHDFDQSSSSFEHHVVYEHNMWAYLFYFLHLKEIKINDYFHLDLYVANMLKRENYDFFPINCALSLTAEQEKYSRIDEISRNVKIIVSNRQNEEREKLRRTNLFKQSQWQKQYQNSQVSSGSYQDLNVDEINFDG 2625          

HSP 3 Score: 253.832 bits (647), Expect = 5.627e-67
Identity = 120/127 (94.49%), Postives = 122/127 (96.06%), Query Frame = 1
Query: 6805 LLIGVKAPDKGYINLTGPISPRHSDFDNYTIIWKPQYVIFREVVMGLGVSHAVIAFLILITYLITDRPTLRTIRSYASRIKQRMVSFYKKEDENDSEKMVDGTNQLVSLFSFMRFLYCCPCQSVESG 7185
            LLIGVKAPDKGYINLTGPISPRHSDFDNYTIIWKPQYVIFREVVMGLGVSHAVIAFLILITYLITDRPTLRTIRSYASRIKQRMVSFYKKEDENDSEKMVDGTNQLVSLFSFMRFLYCC   ++  G
Sbjct: 2200 LLIGVKAPDKGYINLTGPISPRHSDFDNYTIIWKPQYVIFREVVMGLGVSHAVIAFLILITYLITDRPTLRTIRSYASRIKQRMVSFYKKEDENDSEKMVDGTNQLVSLFSFMRFLYCCISLAMSIG 2326          
BLAST of Inositol 1,4,5-trisphosphate receptor type 3 vs. Planmine SMEST
Match: SMESG000023213.1 (SMESG000023213.1)

HSP 1 Score: 428.713 bits (1101), Expect = 0.000e+0
Identity = 269/770 (34.94%), Postives = 433/770 (56.23%), Query Frame = 2
Query: 4703 YTEEIELNLKLQTFIFNCSQLIAGQNTVKAQIKANLRKQYVNLLDQNALPLNLEYQNHLKCFINNSYQKGEIRRYKLVDILIRQLEISGSVERNGKRHTKLDRNSFSKTIKRLDQDALDLRSLQILRGLIYNEECLLPDNWELKIFNSSVQDILKCIKNVQNCLNKLNLSSRTQIHMVNSCDLVKREAITLQSAMLMNANKNVQESLLRYFKGAQEEVFFSAIKYQLQNAFTDLKDQKLMLSQKKSFGDIEKYTCHESDLRIDNLAHILYQQLAEYEIRYEDQNRSLAINRYAYTTTKESFTTRHMRQIYTPAKMKSEINSSSPLICCPRNSSKSNYDMRSTDKSDSLFKNNLQDEY------ELKSVVTKESNSSTDKTIENSAWIKGETLDLMRNDPHQNVKLILQLLSRMCVGQYQGLQNYLRIQPDNRSSVDVISLIVQFLGNIYANVRQSTIDLSIQAFDTIKETIMGNQENRSVVYRAKVVDYANFILRNDEISETCDPNNVLQMFLVIGRVIMALIEENGREETELAKEIQITLDIKAVFKIMTRCLDMME------DTKR------------------------KLIKNKIYDVGFTYFLILARLEDL--------------------CNG-------------KLLKHFQISDQQMKAXXXXXXGSASVEILKGDQLQRIHFRLKHKEVLRESVKEKVKWEVDRTTPSNKIRSFISWSKLILPDMNFQRKIIQNPLLLFVTKQWNAMNYFLTLLSLVINIL 6805
            Y +E+++NLKL+TF  NCS + +G NTV+AQ+K +  + Y  L   + LPL  E+QNHLKCFI  + +K EI+ YK+ D+LI QL IS +    G   T     +     +RL+Q+ LD+R LQ+LR +I+NEE  LP++W+ +     ++  LK I+++QN LN     ++   H+ N  D + +E ++LQ+ ML NAN  +Q+SLL YF   +EEVFF A++ +LQ +  ++K+++L+L+Q+ S     K    E    +     +  + + E  +    Q    A+N    + +  S T + +        +K E N +  +   P+ + + + D +   ++  L  NN  ++       EL  V   ++  + ++ +E      G+    M++D +  ++L+L+LL+R+C GQ+ GLQ YLR QPDN  S ++++ +VQFL  +YAN+ + TIDL  Q F TI E + GNQENR  VY  K++DY N+ILR     + C  + ++++   IG +++++IEEN  + T++A E++ TLD +A++++MT   +M E      D  R                        K +K+K+ +VGF+Y+ ILARL DL                      G             K  K   I+  Q KAFKF+KK S S+E+LKGD LQ++HFR+++K ++RE VKE VKW VDR++PSNKIR F+ WSK IL D+ +Q+K + NP+  F T  W   NY +T+LS+++N++
Sbjct: 1058 YNQEVKMNLKLKTFAANCSLIFSGHNTVQAQLKISSNRDYTTLNGDDYLPLGDEFQNHLKCFIVPNTKKTEIK-YKMADLLINQLHISATTTNFGNLAT-----TGGARKRRLEQEKLDIRCLQLLRAMIHNEERKLPEDWQTRTSEFRIKKGLKNIEDIQNTLNSFKFGTKILPHLANPSDQIAKEVLSLQAMMLFNANHGIQKSLLDYFLETKEEVFFYAVRNRLQLSMANIKERRLLLAQQIS----RKKEAQEQAKNLATTMTLGNRAMKEIRMMISTQRMKNAVN----SLSNNSKTRQKV--------IKKEKNINGKVKHTPKATFRQS-DGKFLGENPRLHDNNDSNKLLGAEAEELAMVTVAKTEEAEEEELEEDEADAGDEAISMKDDGY--IELVLKLLARICDGQHPGLQTYLREQPDNVKSFNLVAEVVQFLNVVYANINKDTIDLVSQVFSTINEFVAGNQENRVTVYDNKIIDYINYILRGGNYPD-CSIHQMIELKQNIGNLVISMIEENNPDATQIANEVKDTLDKEAIYRVMTEAYEMHESESLTPDGIRPKSNTNKSFKTQYIIAKFMVKDEIKDLKSKLCEVGFSYYFILARLYDLDPNLGKKDESVLISRSKSKSIRGRRNRNKVIGDSLIKTTKSLIITPNQQKAFKFYKKNSVSIELLKGDYLQKVHFRIRNKNIIREEVKEVVKWNVDRSSPSNKIRDFMDWSKSILNDIRYQKKAMNNPIAKFFTGGWLLWNYAITILSVILNLM 1801          

HSP 2 Score: 239.58 bits (610), Expect = 0.000e+0
Identity = 149/304 (49.01%), Postives = 221/304 (72.70%), Query Frame = 3
Query: 7155 LLSMSIGGIWI-PYLYVFHLFNVIHNNQLLKGVIASVTKNGRXXXXXXXXXXXXXXXFSIFAFCFLRSTFSSENYLYADTLVQTFVSLVRFGIVGDLYQYTIPHKYYMKTVDTAFTEFSXXXXXXXXXXXXXXXXXXXXXXXXXVDTFSELRDLKYKTEKDMKETCFICSRAGHDFDQSSSSFEHHVVYEHNMWAYLFYFLHLKEIKINDYFHLDLYVANMLKRENYDFFPINCALSLTAEQEKY--SRIDEISRNVKIIVSNRQNEEREKLRRTNLFKXXXXXXXXXXXXXXSGSYQDLNVDE 8057
            +L  S+ G W  PY + FHL N++HNNQLL+GVI++VT+NG+ LIWV IL ++V+Y+++I  F F RS F++E  LY D+L   FVS++RFG+VGDL++  +PH       + +F  FS+++I+ L FFI IT  GLNIIFGIIVDTFSELRDLK+  E DM++TCFICSR  +DF+     FE+HV+ EHNMW+Y+F+F+HL++ K NDY  LD++VA +LK + +DFFP+N AL LTA+ E    S+IDE+ +NV  +++++++E+ E+ R   L +Q +WQK+++    + GS + L+ D+
Sbjct: 1926 ILGFSLAGQWYSPYFFAFHLVNIVHNNQLLQGVISAVTQNGKSLIWVAILGMVVIYLYAIIGFAFFRSGFNTEKNLYCDSLWHCFVSVMRFGLVGDLFENLLPHDS-----EKSFFTFSMLVIYHLSFFILITTIGLNIIFGIIVDTFSELRDLKWTAESDMRDTCFICSRNSYDFEHHGQGFEYHVLNEHNMWSYIFFFIHLQDTKANDYTSLDMFVATLLKEQKFDFFPLNRALCLTAKDEDSTDSKIDELLKNVSTLINHQKSEDSERKRFEELLRQKRWQKRHRGFLSNEGSLEKLDEDD 2224          

HSP 3 Score: 39.2762 bits (90), Expect = 0.000e+0
Identity = 25/88 (28.41%), Postives = 41/88 (46.59%), Query Frame = 1
Query: 6805 LLIGVKAPDKGYINLTGPISPRHSD----FDNYTIIWKPQYVIFREVVMGLGVSHAVIAFLILITYLITDRPTLRTIRSYASRIKQRM 7056
            +L   KAP  G  +    IS  ++     F N    WKP++   +  +   G+ H V+   +L TY + D P+   I+ Y   IK+R+
Sbjct: 1802 MLTVFKAPKDGSFDENFNISKFNNSLPDFFRNPVPDWKPRFENLKSWMFAFGLVHNVLCGFLLFTYFLADHPSPPRIQYYFILIKRRL 1889          

HSP 4 Score: 521.546 bits (1342), Expect = 1.711e-149
Identity = 319/915 (34.86%), Postives = 531/915 (58.03%), Query Frame = 2
Query: 1577 LALEEIRDSLYLDGKPHSLRQKHLRNLQIVDLLVELVLLPFHSKIDAAFTEKIYRASFEILHNYMKGSSIKNSLYFAKYINLFEPKMLENNDLGHKIIEMIAELLRNNQKVLECISFQEIFPFIDNLRINQNFRYLEYLETFCVCNGEPMTQNQIKIAVKWLSEDQRGVFLTDRGQNLNLESNVIYIKTKLDSNWMKLHEFLDITAQIDQENNPLYHQDNKDYFLKQMDLLLALCYGRNQYCTNLIINKLNYISWEQCFAAINSPMIPPYMKTKYFEIIQTMFIDIGRNYAVIESPKFNFIFNQIQGDSSVAVECMFPTPSESVTIKIFKDLSEWIYNFLESTPRMISSNKDFNYLIRIVFITINKLIQYGYY-DSPSLDRICKSLLKLLNGRNDLPFEYDSK-KESLKIRKKLVTKYKNISRYEDSEETRAIVAAKLSGLEILDSILIYERVSVVAKLISRFKKCVQPDLKVQKKRLTGHTHLEACLSNGFDVAQQYKQSNRATKKMVSEIDNLFTTARFLDSEPWTNILIDLAHYQNEMMTQKSLLILHKLYSIKESSFQDTYATFISKTKQSQDLQELMCEYIPALRLHTKSLIGPPDLEKIAAMITEMINVCKIPKS-DSFNPISQRIIVGYGILDIAM-----ETIAQIYRSFDRSKMMYGASEVISLITNLLRHLAISNPSFQEXXXXXXXXXXXXYEHSPPAELADLLRCGLFHNNRTFCGTLKSFQINKIVLMVADTARKNPLVGAAFIHLLESIVAVNNGEVPLKRNQLMVMKFVMKSFNQLVYILDSKSMSRVDLLTIHSASNDAFYFTKVIDLFIACCQGENQYVQSLCQTIMPLDELFDLLTHNDISIIYKRGLLKYFSKVYLSRTNISNQEGIIKNFIESKYCGEILDSIERTTLLTQIILD 4297
            +A  EI++ + ++GK    RQK LRNL+++DLLV+L+ +P + + D A   K++   ++IL+ YM GSS KN+LYFAKYI LFE +ML+ +++  K++++I EL+R+N+K+++ IS  +I  F++ LR N+N+RYLE L+  CVCNG  +  NQ  IA +WL ED+RGV+LT+RGQN++ + N++Y+ T    +W+ LH+FL    Q+D    P Y  +   + L Q+DL  A+CYGRN+YC  LI   L+Y+SWE+ F ++ S ++P  ++ KY E+I  +F+D+G NY+V++ P+ +F++  + G             +    + IF  L +WI  FL+    MI+S  + N LI  V   +N L+++GYY D   +  +   L+ L++G  DLPF  + + KE  K +KK+V KY+   RY  S+ET AIV AK + LE+L  IL +E  + +A  +++FK+C + +  ++KK  +    L   L  GF+  ++   + R  K M+ E+  +F     +  +  TNILI+LAHY+   M Q +L +L+ LYS K+ +FQ    + +  T  S  +   + + +P LR+  KS      + ++  + +E+I  C +PK+ +  +P++QRI+    ++ + M     ET +Q+   + +++      +V+     LL+ +A+  P  Q  +F NLD LL +      +ELA  L+  +F NN+  C  +   QI+KIV + A+  +K P     F+ LL +IV V    + LKRNQ +VMK++M+S++   YIL+    +R  +L      +   Y   +I+L   C +GEN+Y++SLCQTI+ ++++ ++L H +I+   KR  LKY    YL +   S++    +   E K    I +  E    LTQ IL+
Sbjct:    1 MAFREIKEFMLVNGKSVKARQKLLRNLRVIDLLVKLLNMPLYGQPDEANFLKVHLECYDILYTYMIGSSRKNALYFAKYIELFETQMLDKSEISLKVVQLIVELIRDNRKIVDRISKVQINQFVEALRTNENYRYLELLKVLCVCNGVGIVDNQTYIAQRWLLEDRRGVYLTERGQNIHEQPNILYVSTDCMKSWIALHKFL----QVDY---PGYDDEKVQFLLAQLDLFNAICYGRNEYCIRLITKDLSYLSWEEGFLSLQSEILPDDVRAKYCEMIIGLFVDVGNNYSVVDHPERSFVYEYV-GTKDQNKTTTSDQYAAKDLVTIFPALRDWIAAFLDENTYMIASKIEHNMLIEQVLRLLNFLVKFGYYGDVDDVRSLLDKLIGLIDGSRDLPFPPERQGKELSKEKKKIVQKYQQGDRYLQSKETSAIVNAKYAALEVLQMILNFESNARLAGFMAKFKECERNEGLLKKKNPSS---LACALYEGFNPYEKKPSAVRKQKLMIKELREMFENTTQVKIDQMTNILINLAHYKYAKMNQLALEVLNLLYSGKQDTFQAATESLVLMTTDSCCVHREVAKQVPLLRMMAKSKWSDEQVNRMENIFSELIEFCHLPKAPEEPHPMNQRILDSDNVIGVVMEILSVETDSQLTEKYSQTE------KVLRKALQLLKAMALQYPDVQNQIFENLDMLLRV--KLVESELAITLK-EVFVNNQNLCLKILPRQIHKIVSLAAEHQQKAP----EFLDLLCAIVKVEGLGLALKRNQTLVMKYIMQSYSSAAYILEQPMETREAVLKEELGEDHVQYLISLIELLSTCAEGENRYIESLCQTILSVEDILNVLNHPEIANHLKRPFLKYLMFAYLKKPINSSESNTAEILKEKKIWQFIGNLGEEIHYLTQYILE 891          
BLAST of Inositol 1,4,5-trisphosphate receptor type 3 vs. Planmine SMEST
Match: SMESG000023213.1 (SMESG000023213.1)

HSP 1 Score: 430.639 bits (1106), Expect = 0.000e+0
Identity = 268/759 (35.31%), Postives = 433/759 (57.05%), Query Frame = 2
Query: 4703 YTEEIELNLKLQTFIFNCSQLIAGQNTVKAQIKANLRKQYVNLLDQNALPLNLEYQNHLKCFINNSYQKGEIRRYKLVDILIRQLEISGSVERNGKRHTKLDRNSFSKTIKRLDQDALDLRSLQILRGLIYNEECLLPDNWELKIFNSSVQDILKCIKNVQNCLNKLNLSSRTQIHMVNSCDLVKREAITLQSAMLMNANKNVQESLLRYFKGAQEEVFFSAIKYQLQNAFTDLKDQKLMLSQKKSFGDIEKYTCHESDLRIDNLAHILYQQLAEYEIRYEDQNRSLAINRYAYTTTKESFTTRHMRQIYTPAKMKSEINSSSPLICCPRNSSKSNYDMRSTDKSDSLFKNNLQDEY------ELKSVVTKESNSSTDKTIENSAWIKGETLDLMRNDPHQNVKLILQLLSRMCVGQYQGLQNYLRIQPDNRSSVDVISLIVQFLGNIYANVRQSTIDLSIQAFDTIKETIMGNQENRSVVYRAKVVDYANFILRNDEISETCDPNNVLQMFLVIGRVIMALIEENGREETELAKEIQITLDIKAVFKIMTRCLDMME------DTKR------------------------KLIKNKIYDVGFTYFLILARLEDL---------------CNGKLL-------KHFQISDQQMKAXXXXXXGSASVEILKGDQLQRIHFRLKHKEVLRESVKEKVKWEVDRTTPSNKIRSFISWSKLILPDMNFQRKIIQNPLLLFVTKQWNAMNYFLTLLSLVINIL 6805
            Y +E+++NLKL+TF  NCS + +G NTV+AQ+K +  + Y  L   + LPL  E+QNHLKCFI  + +K EI+ YK+ D+LI QL IS +    G   T     +     +RL+Q+ LD+R LQ+LR +I+NEE  LP++W+ +     ++  LK I+++QN LN     ++   H+ N  D + +E ++LQ+ ML NAN  +Q+SLL YF   +EEVFF A++ +LQ +  ++K+++L+L+Q+ S     K    E    +     +  + + E  +    Q    A+N    + +  S T + +        +K E N +  +   P+ + + + D +   ++  L  NN  ++       EL  V   ++  + ++ +E      G+    M++D +  ++L+L+LL+R+C GQ+ GLQ YLR QPDN  S ++++ +VQFL  +YAN+ + TIDL  Q F TI E + GNQENR  VY  K++DY N+ILR     + C  + ++++   IG +++++IEEN  + T++A E++ TLD +A++++MT   +M E      D  R                        K +K+K+ +VGF+Y+ ILARL DL                  K +       K   I+  Q KAFKF+KK S S+E+LKGD LQ++HFR+++K ++RE VKE VKW VDR++PSNKIR F+ WSK IL D+ +Q+K + NP+  F T  W   NY +T+LS+++N++
Sbjct: 1058 YNQEVKMNLKLKTFAANCSLIFSGHNTVQAQLKISSNRDYTTLNGDDYLPLGDEFQNHLKCFIVPNTKKTEIK-YKMADLLINQLHISATTTNFGNLAT-----TGGARKRRLEQEKLDIRCLQLLRAMIHNEERKLPEDWQTRTSEFRIKKGLKNIEDIQNTLNSFKFGTKILPHLANPSDQIAKEVLSLQAMMLFNANHGIQKSLLDYFLETKEEVFFYAVRNRLQLSMANIKERRLLLAQQIS----RKKEAQEQAKNLATTMTLGNRAMKEIRMMISTQRMKNAVN----SLSNNSKTRQKV--------IKKEKNINGKVKHTPKATFRQS-DGKFLGENPRLHDNNDSNKLLGAEAEELAMVTVAKTEEAEEEELEEDEADAGDEAISMKDDGY--IELVLKLLARICDGQHPGLQTYLREQPDNVKSFNLVAEVVQFLNVVYANINKDTIDLVSQVFSTINEFVAGNQENRVTVYDNKIIDYINYILRGGNYPD-CSIHQMIELKQNIGNLVISMIEENNPDATQIANEVKDTLDKEAIYRVMTEAYEMHESESLTPDGIRPKSNTNKSFKTQYIIAKFMVKDEIKDLKSKLCEVGFSYYFILARLYDLDPNLGKKDESVLISRSKSKSIRGRRNRNKGLIITPNQQKAFKFYKKNSVSIELLKGDYLQKVHFRIRNKNIIREEVKEVVKWNVDRSSPSNKIRDFMDWSKSILNDIRYQKKAMNNPIAKFFTGGWLLWNYAITILSVILNLM 1790          

HSP 2 Score: 239.58 bits (610), Expect = 0.000e+0
Identity = 149/304 (49.01%), Postives = 221/304 (72.70%), Query Frame = 3
Query: 7155 LLSMSIGGIWI-PYLYVFHLFNVIHNNQLLKGVIASVTKNGRXXXXXXXXXXXXXXXFSIFAFCFLRSTFSSENYLYADTLVQTFVSLVRFGIVGDLYQYTIPHKYYMKTVDTAFTEFSXXXXXXXXXXXXXXXXXXXXXXXXXVDTFSELRDLKYKTEKDMKETCFICSRAGHDFDQSSSSFEHHVVYEHNMWAYLFYFLHLKEIKINDYFHLDLYVANMLKRENYDFFPINCALSLTAEQEKY--SRIDEISRNVKIIVSNRQNEEREKLRRTNLFKXXXXXXXXXXXXXXSGSYQDLNVDE 8057
            +L  S+ G W  PY + FHL N++HNNQLL+GVI++VT+NG+ LIWV IL ++V+Y+++I  F F RS F++E  LY D+L   FVS++RFG+VGDL++  +PH       + +F  FS+++I+ L FFI IT  GLNIIFGIIVDTFSELRDLK+  E DM++TCFICSR  +DF+     FE+HV+ EHNMW+Y+F+F+HL++ K NDY  LD++VA +LK + +DFFP+N AL LTA+ E    S+IDE+ +NV  +++++++E+ E+ R   L +Q +WQK+++    + GS + L+ D+
Sbjct: 1915 ILGFSLAGQWYSPYFFAFHLVNIVHNNQLLQGVISAVTQNGKSLIWVAILGMVVIYLYAIIGFAFFRSGFNTEKNLYCDSLWHCFVSVMRFGLVGDLFENLLPHDS-----EKSFFTFSMLVIYHLSFFILITTIGLNIIFGIIVDTFSELRDLKWTAESDMRDTCFICSRNSYDFEHHGQGFEYHVLNEHNMWSYIFFFIHLQDTKANDYTSLDMFVATLLKEQKFDFFPLNRALCLTAKDEDSTDSKIDELLKNVSTLINHQKSEDSERKRFEELLRQKRWQKRHRGFLSNEGSLEKLDEDD 2213          

HSP 3 Score: 39.2762 bits (90), Expect = 0.000e+0
Identity = 25/88 (28.41%), Postives = 41/88 (46.59%), Query Frame = 1
Query: 6805 LLIGVKAPDKGYINLTGPISPRHSD----FDNYTIIWKPQYVIFREVVMGLGVSHAVIAFLILITYLITDRPTLRTIRSYASRIKQRM 7056
            +L   KAP  G  +    IS  ++     F N    WKP++   +  +   G+ H V+   +L TY + D P+   I+ Y   IK+R+
Sbjct: 1791 MLTVFKAPKDGSFDENFNISKFNNSLPDFFRNPVPDWKPRFENLKSWMFAFGLVHNVLCGFLLFTYFLADHPSPPRIQYYFILIKRRL 1878          

HSP 4 Score: 521.546 bits (1342), Expect = 1.418e-149
Identity = 319/915 (34.86%), Postives = 531/915 (58.03%), Query Frame = 2
Query: 1577 LALEEIRDSLYLDGKPHSLRQKHLRNLQIVDLLVELVLLPFHSKIDAAFTEKIYRASFEILHNYMKGSSIKNSLYFAKYINLFEPKMLENNDLGHKIIEMIAELLRNNQKVLECISFQEIFPFIDNLRINQNFRYLEYLETFCVCNGEPMTQNQIKIAVKWLSEDQRGVFLTDRGQNLNLESNVIYIKTKLDSNWMKLHEFLDITAQIDQENNPLYHQDNKDYFLKQMDLLLALCYGRNQYCTNLIINKLNYISWEQCFAAINSPMIPPYMKTKYFEIIQTMFIDIGRNYAVIESPKFNFIFNQIQGDSSVAVECMFPTPSESVTIKIFKDLSEWIYNFLESTPRMISSNKDFNYLIRIVFITINKLIQYGYY-DSPSLDRICKSLLKLLNGRNDLPFEYDSK-KESLKIRKKLVTKYKNISRYEDSEETRAIVAAKLSGLEILDSILIYERVSVVAKLISRFKKCVQPDLKVQKKRLTGHTHLEACLSNGFDVAQQYKQSNRATKKMVSEIDNLFTTARFLDSEPWTNILIDLAHYQNEMMTQKSLLILHKLYSIKESSFQDTYATFISKTKQSQDLQELMCEYIPALRLHTKSLIGPPDLEKIAAMITEMINVCKIPKS-DSFNPISQRIIVGYGILDIAM-----ETIAQIYRSFDRSKMMYGASEVISLITNLLRHLAISNPSFQEXXXXXXXXXXXXYEHSPPAELADLLRCGLFHNNRTFCGTLKSFQINKIVLMVADTARKNPLVGAAFIHLLESIVAVNNGEVPLKRNQLMVMKFVMKSFNQLVYILDSKSMSRVDLLTIHSASNDAFYFTKVIDLFIACCQGENQYVQSLCQTIMPLDELFDLLTHNDISIIYKRGLLKYFSKVYLSRTNISNQEGIIKNFIESKYCGEILDSIERTTLLTQIILD 4297
            +A  EI++ + ++GK    RQK LRNL+++DLLV+L+ +P + + D A   K++   ++IL+ YM GSS KN+LYFAKYI LFE +ML+ +++  K++++I EL+R+N+K+++ IS  +I  F++ LR N+N+RYLE L+  CVCNG  +  NQ  IA +WL ED+RGV+LT+RGQN++ + N++Y+ T    +W+ LH+FL    Q+D    P Y  +   + L Q+DL  A+CYGRN+YC  LI   L+Y+SWE+ F ++ S ++P  ++ KY E+I  +F+D+G NY+V++ P+ +F++  + G             +    + IF  L +WI  FL+    MI+S  + N LI  V   +N L+++GYY D   +  +   L+ L++G  DLPF  + + KE  K +KK+V KY+   RY  S+ET AIV AK + LE+L  IL +E  + +A  +++FK+C + +  ++KK  +    L   L  GF+  ++   + R  K M+ E+  +F     +  +  TNILI+LAHY+   M Q +L +L+ LYS K+ +FQ    + +  T  S  +   + + +P LR+  KS      + ++  + +E+I  C +PK+ +  +P++QRI+    ++ + M     ET +Q+   + +++      +V+     LL+ +A+  P  Q  +F NLD LL +      +ELA  L+  +F NN+  C  +   QI+KIV + A+  +K P     F+ LL +IV V    + LKRNQ +VMK++M+S++   YIL+    +R  +L      +   Y   +I+L   C +GEN+Y++SLCQTI+ ++++ ++L H +I+   KR  LKY    YL +   S++    +   E K    I +  E    LTQ IL+
Sbjct:    1 MAFREIKEFMLVNGKSVKARQKLLRNLRVIDLLVKLLNMPLYGQPDEANFLKVHLECYDILYTYMIGSSRKNALYFAKYIELFETQMLDKSEISLKVVQLIVELIRDNRKIVDRISKVQINQFVEALRTNENYRYLELLKVLCVCNGVGIVDNQTYIAQRWLLEDRRGVYLTERGQNIHEQPNILYVSTDCMKSWIALHKFL----QVDY---PGYDDEKVQFLLAQLDLFNAICYGRNEYCIRLITKDLSYLSWEEGFLSLQSEILPDDVRAKYCEMIIGLFVDVGNNYSVVDHPERSFVYEYV-GTKDQNKTTTSDQYAAKDLVTIFPALRDWIAAFLDENTYMIASKIEHNMLIEQVLRLLNFLVKFGYYGDVDDVRSLLDKLIGLIDGSRDLPFPPERQGKELSKEKKKIVQKYQQGDRYLQSKETSAIVNAKYAALEVLQMILNFESNARLAGFMAKFKECERNEGLLKKKNPSS---LACALYEGFNPYEKKPSAVRKQKLMIKELREMFENTTQVKIDQMTNILINLAHYKYAKMNQLALEVLNLLYSGKQDTFQAATESLVLMTTDSCCVHREVAKQVPLLRMMAKSKWSDEQVNRMENIFSELIEFCHLPKAPEEPHPMNQRILDSDNVIGVVMEILSVETDSQLTEKYSQTE------KVLRKALQLLKAMALQYPDVQNQIFENLDMLLRV--KLVESELAITLK-EVFVNNQNLCLKILPRQIHKIVSLAAEHQQKAP----EFLDLLCAIVKVEGLGLALKRNQTLVMKYIMQSYSSAAYILEQPMETREAVLKEELGEDHVQYLISLIELLSTCAEGENRYIESLCQTILSVEDILNVLNHPEIANHLKRPFLKYLMFAYLKKPINSSESNTAEILKEKKIWQFIGNLGEEIHYLTQYILE 891          
The following BLAST results are available for this feature:
BLAST of Inositol 1,4,5-trisphosphate receptor type 3 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ITPR24.868e-2524.15inositol 1,4,5-trisphosphate receptor type 2 [Sour... [more]
ITPR12.850e-2225.97inositol 1,4,5-trisphosphate receptor type 1 [Sour... [more]
ITPR12.959e-2226.03inositol 1,4,5-trisphosphate receptor type 1 [Sour... [more]
ITPR12.959e-2226.03inositol 1,4,5-trisphosphate receptor type 1 [Sour... [more]
ITPR12.959e-2226.03inositol 1,4,5-trisphosphate receptor type 1 [Sour... [more]
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BLAST of Inositol 1,4,5-trisphosphate receptor type 3 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
itr-12.473e-1820.53Inositol 1,4,5-trisphosphate receptor itr-1 [Sour... [more]
itr-12.718e-1820.53Inositol 1,4,5-trisphosphate receptor itr-1 [Sour... [more]
itr-12.947e-1820.39Inositol 1,4,5-trisphosphate receptor itr-1 [Sour... [more]
itr-13.320e-1820.53Inositol 1,4,5-trisphosphate receptor itr-1 [Sour... [more]
itr-13.729e-1820.53Inositol 1,4,5-trisphosphate receptor itr-1 [Sour... [more]
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BLAST of Inositol 1,4,5-trisphosphate receptor type 3 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Itp-r83A5.071e-1621.75gene:FBgn0010051 transcript:FBtr0078687[more]
Itp-r83A5.701e-1621.75gene:FBgn0010051 transcript:FBtr0078686[more]
Itp-r83A5.701e-1621.75gene:FBgn0010051 transcript:FBtr0344265[more]
RyR1.504e-1126.40gene:FBgn0011286 transcript:FBtr0088639[more]
RyR1.517e-1126.40gene:FBgn0011286 transcript:FBtr0088638[more]
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BLAST of Inositol 1,4,5-trisphosphate receptor type 3 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
itpr1b1.707e-3022.59inositol 1,4,5-trisphosphate receptor, type 1b [So... [more]
itpr1b2.801e-3022.59inositol 1,4,5-trisphosphate receptor, type 1b [So... [more]
itpr1b2.976e-3022.59inositol 1,4,5-trisphosphate receptor, type 1b [So... [more]
itpr1b7.120e-2922.32inositol 1,4,5-trisphosphate receptor, type 1b [So... [more]
itpr29.950e-2922.80inositol 1,4,5-trisphosphate receptor, type 2 [Sou... [more]
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BLAST of Inositol 1,4,5-trisphosphate receptor type 3 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
c1qbp1.775e-3024.01complement component 1, q subcomponent binding pro... [more]
sfi12.520e-3025.72SFI1 centrin binding protein [Source:Xenbase;Acc:X... [more]
sfi13.025e-3025.94SFI1 centrin binding protein [Source:Xenbase;Acc:X... [more]
sfi11.745e-2825.39SFI1 centrin binding protein [Source:Xenbase;Acc:X... [more]
sfi14.625e-2825.21SFI1 centrin binding protein [Source:Xenbase;Acc:X... [more]
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BLAST of Inositol 1,4,5-trisphosphate receptor type 3 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Itpr13.936e-3023.15inositol 1,4,5-trisphosphate receptor 1 [Source:MG... [more]
Itpr14.104e-3023.15inositol 1,4,5-trisphosphate receptor 1 [Source:MG... [more]
Itpr25.494e-2624.29inositol 1,4,5-triphosphate receptor 2 [Source:MGI... [more]
Itpr31.754e-2323.64inositol 1,4,5-triphosphate receptor 3 [Source:MGI... [more]
Itpr22.305e-2123.30inositol 1,4,5-triphosphate receptor 2 [Source:MGI... [more]
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BLAST of Inositol 1,4,5-trisphosphate receptor type 3 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|P11881|ITPR1_MOUSE2.753e-2923.15Inositol 1,4,5-trisphosphate receptor type 1 OS=Mu... [more]
sp|Q8WN96|ITPR2_BOVIN1.463e-2524.37Inositol 1,4,5-trisphosphate receptor type 2 OS=Bo... [more]
sp|Q14571|ITPR2_HUMAN2.338e-2424.15Inositol 1,4,5-trisphosphate receptor type 2 OS=Ho... [more]
sp|Q63269|ITPR3_RAT5.960e-2323.89Inositol 1,4,5-trisphosphate receptor type 3 OS=Ra... [more]
sp|P70227|ITPR3_MOUSE1.227e-2223.64Inositol 1,4,5-trisphosphate receptor type 3 OS=Mu... [more]
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BLAST of Inositol 1,4,5-trisphosphate receptor type 3 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A267E8351.772e-4634.48Uncharacterized protein (Fragment) OS=Macrostomum ... [more]
A0A1S3H9B82.590e-4932.18inositol 1,4,5-trisphosphate receptor type 3 isofo... [more]
A0A1S3H6W62.908e-4932.11inositol 1,4,5-trisphosphate receptor type 3 isofo... [more]
A0A1S3H9B52.744e-4931.92inositol 1,4,5-trisphosphate receptor type 3 isofo... [more]
A0A1S3H6U82.590e-4931.88inositol 1,4,5-trisphosphate receptor type 3 isofo... [more]
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BLAST of Inositol 1,4,5-trisphosphate receptor type 3 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
itpr1a2.532e-2822.82inositol 1,4,5-trisphosphate receptor, type 1a [So... [more]
itpr23.309e-2822.80inositol 1,4,5-trisphosphate receptor, type 2 [Sou... [more]
itpr1b1.513e-2723.93inositol 1,4,5-trisphosphate receptor, type 1b [So... [more]
ryr34.767e-1428.75ryanodine receptor 3 [Source:ZFIN;Acc:ZDB-GENE-041... [more]
ryr1b1.769e-1328.51ryanodine receptor 1b (skeletal) [Source:ZFIN;Acc:... [more]
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BLAST of Inositol 1,4,5-trisphosphate receptor type 3 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 4
Match NameE-valueIdentityDescription
ENSPMAT00000003582.18.411e-2024.62pep scaffold:Pmarinus_7.0:GL477251:10655:41631:-1 ... [more]
ENSPMAT00000007822.14.224e-1742.57pep scaffold:Pmarinus_7.0:GL476823:160879:181935:-... [more]
ENSPMAT00000007816.11.031e-1642.57pep scaffold:Pmarinus_7.0:GL476823:160879:205429:-... [more]
ENSPMAT00000010602.16.145e-1023.67pep scaffold:Pmarinus_7.0:GL476450:29:322425:-1 ge... [more]
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BLAST of Inositol 1,4,5-trisphosphate receptor type 3 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Inositol 1,4,5-trisphosphate receptor type 3 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 2
Match NameE-valueIdentityDescription
EDO378763.659e-2225.68Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO285927.245e-1528.85Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Inositol 1,4,5-trisphosphate receptor type 3 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
itpr1b4.000e-3024.14inositol 1,4,5-trisphosphate receptor type 1 [Sour... [more]
itpr1a5.263e-2522.55inositol 1,4,5-trisphosphate receptor type 1 [Sour... [more]
itpr36.846e-2134.86inositol 1,4,5-trisphosphate receptor type 3 [Sour... [more]
ENSORLT00000014249.23.481e-1824.02pep primary_assembly:ASM223467v1:6:21638618:216483... [more]
itpr26.436e-1829.47inositol 1,4,5-trisphosphate receptor, type 2 [Sou... [more]
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BLAST of Inositol 1,4,5-trisphosphate receptor type 3 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000070557.11.459e-14499.59SMESG000070557.1[more]
SMESG000070557.11.104e-14499.55SMESG000070557.1[more]
SMESG000070557.11.172e-14499.23SMESG000070557.1[more]
SMESG000023213.11.711e-14934.94SMESG000023213.1[more]
SMESG000023213.11.418e-14935.31SMESG000023213.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30018386 ID=SMED30018386|Name=Inositol 1,4,5-trisphosphate receptor type 3|organism=Schmidtea mediterranea sexual|type=transcript|length=8298bp
TGTTTACCGGCGATAGATCTCAAGCAGGTGTTTGATGCTAAAAACAATGC
ACACACATTCATGAAAGATTCATTACATATACAAATCTTATTATTGAATA
AATCGAATTTCTTTTTAAACAATATTTATATGTTATTTTCTGGAAATCGA
TATTTTTCAACTCATGAATGACTATTTATCGTATGGAGACAGGATTTGTC
TTTATTGTGAGGAAACGAATGGATTTATTAACAGCAACAATTCGAGTTCC
CATTACAATGAATTGAGAATATTTTCAAAACAGGACAAATTTAACCCGGA
AAATGTTTCAGATATTCAAGAAATCATATTCGAAGTGGTCATTCAGAATC
GGTACAAATTATACAAAAAATATATGAAGAACTACAAGGATATCAACAAC
AAATCAGAAAATTTGGAATTGAAAATTCAAGCCGAACAAGCTAAGGCCAC
AGTTATATCGGAAGAAAACGATAACGCTTTGGAAAATCGCAGAAATTTAG
GAAAGACGGTTCATTATGGTGATGTTATACAACTGCGACACGTTTACACA
AGGAAATATATACACGTTAATATTGCTAAGACAAGTTCGAAGGATCAAAA
CAGCATGATTCTCAATCTCCAAAGCCACAATTTAAAGTCAGCTCAGTTTA
AAATCGTTCCTAGATACAAAGTTAAATATGAAGGTGAACCGGTGCAATTT
ATGGACCTTGTTACTTTTGAAAGTTTAAAAGCACCTTCTCATTATTTTCA
TGCCAGTGATTTATACCAAATTGATAATTTTTTCCATGGGGCAGCGCTCA
ATTTAGCAACAGAGCAATCTGGATTCACACTAATTAAATCGGCTTCGGAC
ACCCATATTATGGAGGAAGATAATTTCCTCAGAGGTGGTGATTATATTCA
AATTATTCACAAAGAAATAGATGGGTATATTGAATCAGAAGGAATACAAG
GAGGAATGAAAAAGGCAGATATTTATTTACGCATTAGGAAGTCGGACAAA
TTTCAAACTCTAACAAACTCTCGGCTCTCTTCTTCCGCCAACACTTTCTG
GCAAGTAGAGATTGAAAAAGTTAGGCTAAGCACTGAAATTGGTCAATGGA
GCAGTAATTTTCGCTTCCGCCATGCGACAAATCGTTTGTATCTCTCTGTA
AAGAAAGACCTTTCAGTATCAATGACAAAGAATGCCACTAATCCTAACAC
TGTGTTTCGCCTATACCCTCAAAATATTGATAAACTTATAATTCCTTACG
GTAGATACTTTAGAATGGAGCATGTCCTTACAGGAACCTGGATTCATGCT
AATAAAGAGCAAGTTTATGTCAAACCTAACCAATCAAAATATGATGACGC
CGCGGAAAAGTGTCTTGGAAATTTGAAATACGAAACCAACGAACTAAGAG
AACTATTCTGCGTTCACCAAAGACTGTACGATGATGCATTTGTCGTGTTC
AAAGTACCAACAGAAATCGTCGAATCTTTCAATCTTCTATCTGGTTATTT
TCCTTTGATTAAAAACCTCATAGTCGATAGGAAAAAAGCTGTTCCATTTA
CAGCCTCACAGAGTTACAGATACAAATTAGCTTTGGAGGAGATTAGAGAC
AGCCTTTATTTGGATGGAAAGCCACATAGCTTGCGTCAGAAACATTTAAG
GAATCTTCAAATTGTAGATCTTCTTGTTGAATTAGTTCTCTTGCCATTTC
ACAGTAAGATTGATGCGGCTTTTACAGAAAAAATTTACCGCGCCAGTTTT
GAAATCCTTCACAATTACATGAAAGGTTCAAGTATCAAAAATTCGCTCTA
TTTTGCCAAGTACATCAATCTTTTTGAACCGAAGATGTTAGAGAATAATG
ATCTCGGGCATAAAATCATTGAAATGATTGCCGAATTACTGAGAAATAAT
CAAAAGGTTCTCGAGTGCATCAGTTTTCAGGAGATTTTCCCATTCATTGA
TAATTTAAGAATCAATCAGAACTTTCGCTATCTCGAATATCTGGAAACGT
TCTGCGTGTGCAATGGGGAGCCAATGACTCAGAACCAAATAAAGATCGCC
GTAAAATGGTTGTCAGAAGATCAACGAGGGGTCTTTCTCACTGACCGTGG
ACAGAATCTGAATTTAGAATCGAATGTTATCTACATAAAGACTAAACTAG
ATTCAAATTGGATGAAATTGCATGAATTTCTGGACATAACAGCACAAATT
GATCAGGAAAACAATCCACTCTATCACCAAGACAACAAAGATTATTTCCT
CAAGCAGATGGATCTTTTGCTGGCACTATGTTATGGTCGAAATCAATACT
GCACCAATTTAATAATCAATAAATTAAATTATATTAGTTGGGAGCAGTGT
TTCGCCGCCATCAATAGTCCAATGATCCCTCCTTACATGAAGACAAAGTA
TTTTGAAATTATTCAAACTATGTTTATTGACATTGGGAGAAATTATGCTG
TTATTGAGAGCCCCAAGTTCAATTTTATTTTCAATCAAATTCAAGGCGAT
TCCTCAGTTGCAGTTGAGTGCATGTTTCCAACTCCCTCGGAAAGTGTAAC
AATCAAAATTTTCAAAGATTTGAGTGAATGGATTTATAACTTTTTGGAAA
GTACTCCTCGCATGATCTCATCGAATAAAGATTTCAATTATCTCATCCGA
ATTGTGTTCATAACCATTAACAAGTTGATACAATATGGATATTATGACAG
TCCAAGTTTGGACAGAATTTGCAAATCCCTTCTAAAATTGCTCAACGGAA
GAAATGATCTACCATTTGAATATGATAGCAAAAAAGAATCATTGAAAATA
AGAAAAAAACTTGTAACCAAATATAAGAATATTTCTCGATACGAAGATTC
AGAAGAAACTAGAGCGATTGTTGCTGCAAAATTATCAGGATTGGAAATAT
TGGACTCGATTCTCATCTACGAACGAGTATCAGTAGTAGCGAAGCTTATA
AGCAGATTTAAAAAATGCGTCCAACCAGATTTGAAAGTACAAAAGAAAAG
ACTTACCGGCCATACGCATTTAGAAGCTTGCTTATCCAATGGATTTGATG
TTGCTCAACAATACAAGCAATCTAACAGGGCAACCAAGAAAATGGTGTCA
GAAATAGATAATTTGTTTACAACTGCTCGATTTCTAGACTCGGAACCGTG
GACCAACATCTTGATTGATTTAGCGCACTATCAGAATGAAATGATGACCC
AAAAATCTCTTCTCATCCTTCACAAGCTGTATTCCATCAAAGAATCGAGT
TTCCAAGACACTTATGCCACATTTATCTCAAAAACGAAACAGTCCCAGGA
TCTGCAAGAATTGATGTGTGAATATATTCCTGCGCTGAGACTACATACTA
AATCATTAATTGGGCCCCCAGATCTAGAGAAAATAGCGGCAATGATTACA
GAAATGATAAACGTTTGCAAAATCCCAAAATCTGACAGTTTTAATCCGAT
TTCACAGAGAATAATAGTTGGTTACGGAATTCTTGACATTGCCATGGAGA
CAATTGCTCAGATATATCGGTCCTTTGACAGGTCTAAAATGATGTATGGA
GCCTCTGAAGTTATCAGCTTAATCACAAATCTTTTGCGTCATCTCGCTAT
TTCAAATCCATCTTTCCAAGAAAATCTTTTTAACAATCTTGATACATTGC
TTGATCTTTATGAACACTCACCACCGGCAGAATTGGCTGACCTTCTCAGA
TGTGGATTGTTCCATAATAACCGCACATTTTGTGGCACATTGAAATCCTT
CCAAATAAACAAGATCGTACTGATGGTGGCAGATACAGCTCGAAAAAATC
CATTAGTTGGTGCGGCATTTATTCATCTGCTTGAGTCAATTGTTGCCGTT
AATAATGGTGAAGTTCCTTTGAAAAGAAACCAGTTGATGGTCATGAAATT
TGTCATGAAGAGCTTCAATCAACTTGTATATATTTTGGACTCAAAATCTA
TGTCACGGGTGGACTTACTCACTATTCATTCTGCATCAAATGATGCTTTC
TATTTCACAAAGGTCATTGACTTGTTTATTGCTTGTTGTCAGGGAGAAAA
CCAGTACGTTCAGTCTCTGTGTCAAACAATTATGCCTCTTGATGAGCTAT
TTGATCTCTTAACTCACAACGACATCAGTATTATTTACAAGAGAGGCTTG
CTTAAATATTTTTCTAAAGTTTACCTCAGTCGGACGAATATTTCTAATCA
AGAAGGAATTATCAAAAATTTCATCGAGTCTAAATATTGTGGAGAAATTC
TTGACAGTATTGAGAGGACCACTCTGCTTACTCAAATTATTCTTGATAAA
ACAGAACATTTTAATCTGTTGCCAATTCTTAAGAAGGAATTTATATTAAA
GCCTCCGACGGAATTCCAGGTCTCAGAGAACATACAAATGCACCTTCATT
ACATCATTTTTGGATCATCGATTTTTATGGCTAGTCTTTGTTCGGCTTTT
TCAATAATGGAAATATCCCCGGCACCGGAACTGATGAAGGTCATAAAATC
TATTAATCACATTACAATGGATATATTTTCTCAAATGTGGAAATTTCAGT
TGCATCCGAGCGTATTTTCCGTCATAACGGAATCTGTTTTACAAATAATT
TCGTACACCGACACTTCGGATTTGGAAGCGAAGACCATGGCATTGCAACA
TTGTAAGCCTCAAATCATGGACTTTGATCCAAGAAAGGAGATTGATAACC
TTTATACCGAAGAGATAGAGCTTAATTTGAAACTGCAGACATTCATCTTT
AACTGTAGCCAGCTAATAGCCGGTCAAAATACTGTGAAGGCTCAGATCAA
AGCCAATTTGAGAAAACAATATGTGAATCTCTTGGACCAAAACGCTCTTC
CTTTAAATCTGGAATATCAAAACCATTTAAAATGCTTTATCAACAATAGC
TACCAGAAAGGAGAAATAAGGAGATATAAATTAGTTGATATTCTTATCAG
GCAACTTGAAATATCGGGATCAGTTGAAAGAAATGGAAAGAGGCATACTA
AACTTGACAGAAATAGTTTCAGTAAAACCATAAAAAGATTGGATCAAGAT
GCATTGGACCTCAGAAGTTTACAAATTTTAAGGGGATTGATCTATAACGA
AGAGTGTCTACTTCCGGATAATTGGGAATTGAAGATTTTTAATTCATCTG
TTCAAGACATTTTGAAATGCATTAAAAATGTTCAAAATTGTTTAAACAAA
CTCAATTTATCAAGTAGAACCCAAATTCATATGGTTAACTCCTGCGATTT
GGTTAAAAGAGAGGCCATTACTCTCCAATCAGCAATGCTAATGAATGCCA
ACAAAAATGTTCAAGAATCTCTTTTAAGGTATTTTAAAGGAGCCCAAGAA
GAAGTATTTTTCAGTGCTATCAAATATCAATTGCAGAATGCATTCACCGA
CCTCAAAGATCAGAAATTAATGTTATCTCAAAAGAAATCTTTTGGAGATA
TCGAGAAGTACACCTGCCATGAAAGTGATCTCAGAATCGACAATCTTGCA
CACATCCTTTATCAACAACTAGCAGAATACGAAATTCGATATGAAGATCA
GAATAGAAGTTTAGCTATTAATAGGTATGCATACACGACGACTAAGGAGA
GTTTCACGACCAGACATATGCGGCAGATCTATACTCCAGCAAAGATGAAG
AGCGAAATTAACTCCAGTTCACCTTTGATCTGTTGTCCACGAAATTCCAG
TAAATCAAATTATGATATGAGGAGCACAGACAAATCTGATTCTTTATTCA
AGAACAATTTGCAGGATGAATACGAGTTGAAAAGCGTTGTAACCAAGGAA
TCAAATTCCTCGACGGATAAGACTATTGAAAACAGTGCATGGATAAAAGG
GGAAACTCTGGATTTGATGAGGAATGATCCTCACCAAAATGTGAAATTAA
TTCTTCAGTTATTATCTCGGATGTGTGTCGGTCAGTATCAAGGCTTGCAA
AATTACTTGAGAATCCAGCCGGATAACCGAAGTTCTGTCGATGTTATCAG
TCTAATTGTGCAGTTTCTCGGAAATATATATGCGAACGTTCGTCAGTCAA
CTATCGACTTAAGTATACAGGCTTTTGATACGATCAAGGAAACAATAATG
GGAAATCAAGAGAATCGCTCAGTCGTCTATAGAGCTAAGGTTGTTGACTA
TGCCAATTTCATCCTAAGAAATGATGAAATCAGTGAGACCTGTGACCCGA
ATAACGTCCTGCAAATGTTCCTAGTTATTGGTCGAGTGATCATGGCGTTG
ATTGAAGAGAATGGGAGGGAGGAAACAGAATTAGCTAAGGAAATTCAAAT
AACCCTTGACATAAAAGCGGTATTTAAAATAATGACTCGATGCTTGGACA
TGATGGAGGACACAAAACGAAAGTTGATTAAAAACAAGATTTACGATGTA
GGATTCACGTATTTTCTCATTCTCGCTCGATTGGAAGATCTGTGTAACGG
GAAACTCCTCAAACATTTCCAGATCAGTGACCAGCAAATGAAGGCATTCA
AGTTTTTTAAAAAAGGATCTGCGTCAGTTGAGATATTGAAAGGAGACCAA
TTACAAAGGATTCATTTTCGGCTAAAGCACAAAGAGGTATTAAGAGAGTC
AGTTAAAGAAAAGGTGAAATGGGAAGTTGATCGAACAACTCCTAGTAATA
AGATTCGATCCTTCATTTCATGGTCAAAACTTATTCTGCCGGATATGAAT
TTTCAGAGGAAAATCATTCAAAATCCTCTTTTGCTATTTGTTACCAAACA
ATGGAATGCCATGAACTATTTCCTTACATTGCTCAGTCTTGTTATAAATA
TACTTTATTGATAGGGGTGAAGGCCCCTGATAAAGGATATATTAATCTAA
CTGGGCCCATTTCGCCTCGACATTCGGATTTCGACAATTACACTATTATA
TGGAAACCTCAATATGTAATCTTTCGAGAGGTTGTAATGGGATTGGGGGT
TTCCCATGCGGTTATAGCTTTTCTGATTCTCATCACCTATCTCATTACCG
ATAGGCCAACATTGAGAACTATCCGAAGCTATGCTAGCCGGATTAAACAG
AGAATGGTAAGTTTTTATAAAAAAGAGGACGAAAACGATTCAGAGAAAAT
GGTAGATGGGACAAATCAACTCGTTTCTTTGTTTTCCTTTATGAGATTTC
TCTATTGCTGTCCATGTCAATCGGTGGAATCTGGATACCTTACTTGTACG
TGTTTCACCTGTTCAACGTCATTCACAACAACCAATTGCTTAAAGGTGTA
ATAGCCTCAGTTACTAAAAACGGCCGAGTTCTCATTTGGGTCATGATACT
GATGGTGATTGTTATGTATATTTTTTCGATTTTCGCATTTTGTTTTTTGC
GATCGACTTTTAGTTCAGAAAATTATTTATATGCTGACACCTTGGTCCAA
ACATTCGTGTCGCTTGTCCGGTTTGGAATCGTTGGAGATCTCTACCAGTA
TACGATTCCGCATAAATATTACATGAAAACAGTTGATACTGCTTTTACTG
AATTCAGTCTGATTTTGATTTTTCAATTATTTTTCTTCATTTTCATCACA
ATTACTGGGCTCAATATCATATTCGGTATCATTGTTGATACGTTTTCCGA
GCTGAGGGATCTGAAGTACAAAACAGAAAAAGATATGAAAGAGACTTGTT
TTATTTGTTCTCGTGCTGGTCACGATTTTGATCAATCAAGTAGCAGTTTC
GAACACCATGTCGTTTATGAGCACAACATGTGGGCCTACCTCTTCTACTT
CCTCCATTTGAAGGAGATCAAGATCAATGATTATTTTCACCTAGATTTGT
ATGTGGCAAATATGCTGAAAAGAGAAAACTATGATTTTTTCCCAATAAAC
TGCGCCCTGTCGTTGACGGCAGAACAAGAAAAATATTCGAGAATTGATGA
AATAAGTAGAAATGTGAAAATTATTGTCAGCAATCGCCAAAATGAAGAGC
GTGAGAAATTACGTAGAACTAATCTCTTCAAGCAGTCTCAGTGGCAAAAA
CAGTACCAAAATTCACAGGTTTCCTCTGGTTCCTATCAAGATTTAAACGT
GGACGAGATTAATTTTGATGGACATTCAAATGAAATAGAGAGATCCCCGT
CTCTACATGAAAGACATCTGTCAGTTCATTCGTCCTTAGAAATCCAGCCA
CCTAGTCAGACCAGATTTAAATCTCCAACAAGTACCCCTTCACCTGGAAC
TAAGAGGAACTTATTGAGTTTATCAACTTCCAGTAAATAAAATTATTTGT
ATTACTAGCAACATCAGTCAGAATGTTACTTGACAAGAAATCTCATAC
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protein sequence of SMED30018386-orf-1

>SMED30018386-orf-1 ID=SMED30018386-orf-1|Name=SMED30018386-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=2216bp
MNDYLSYGDRICLYCEETNGFINSNNSSSHYNELRIFSKQDKFNPENVSD
IQEIIFEVVIQNRYKLYKKYMKNYKDINNKSENLELKIQAEQAKATVISE
ENDNALENRRNLGKTVHYGDVIQLRHVYTRKYIHVNIAKTSSKDQNSMIL
NLQSHNLKSAQFKIVPRYKVKYEGEPVQFMDLVTFESLKAPSHYFHASDL
YQIDNFFHGAALNLATEQSGFTLIKSASDTHIMEEDNFLRGGDYIQIIHK
EIDGYIESEGIQGGMKKADIYLRIRKSDKFQTLTNSRLSSSANTFWQVEI
EKVRLSTEIGQWSSNFRFRHATNRLYLSVKKDLSVSMTKNATNPNTVFRL
YPQNIDKLIIPYGRYFRMEHVLTGTWIHANKEQVYVKPNQSKYDDAAEKC
LGNLKYETNELRELFCVHQRLYDDAFVVFKVPTEIVESFNLLSGYFPLIK
NLIVDRKKAVPFTASQSYRYKLALEEIRDSLYLDGKPHSLRQKHLRNLQI
VDLLVELVLLPFHSKIDAAFTEKIYRASFEILHNYMKGSSIKNSLYFAKY
INLFEPKMLENNDLGHKIIEMIAELLRNNQKVLECISFQEIFPFIDNLRI
NQNFRYLEYLETFCVCNGEPMTQNQIKIAVKWLSEDQRGVFLTDRGQNLN
LESNVIYIKTKLDSNWMKLHEFLDITAQIDQENNPLYHQDNKDYFLKQMD
LLLALCYGRNQYCTNLIINKLNYISWEQCFAAINSPMIPPYMKTKYFEII
QTMFIDIGRNYAVIESPKFNFIFNQIQGDSSVAVECMFPTPSESVTIKIF
KDLSEWIYNFLESTPRMISSNKDFNYLIRIVFITINKLIQYGYYDSPSLD
RICKSLLKLLNGRNDLPFEYDSKKESLKIRKKLVTKYKNISRYEDSEETR
AIVAAKLSGLEILDSILIYERVSVVAKLISRFKKCVQPDLKVQKKRLTGH
THLEACLSNGFDVAQQYKQSNRATKKMVSEIDNLFTTARFLDSEPWTNIL
IDLAHYQNEMMTQKSLLILHKLYSIKESSFQDTYATFISKTKQSQDLQEL
MCEYIPALRLHTKSLIGPPDLEKIAAMITEMINVCKIPKSDSFNPISQRI
IVGYGILDIAMETIAQIYRSFDRSKMMYGASEVISLITNLLRHLAISNPS
FQENLFNNLDTLLDLYEHSPPAELADLLRCGLFHNNRTFCGTLKSFQINK
IVLMVADTARKNPLVGAAFIHLLESIVAVNNGEVPLKRNQLMVMKFVMKS
FNQLVYILDSKSMSRVDLLTIHSASNDAFYFTKVIDLFIACCQGENQYVQ
SLCQTIMPLDELFDLLTHNDISIIYKRGLLKYFSKVYLSRTNISNQEGII
KNFIESKYCGEILDSIERTTLLTQIILDKTEHFNLLPILKKEFILKPPTE
FQVSENIQMHLHYIIFGSSIFMASLCSAFSIMEISPAPELMKVIKSINHI
TMDIFSQMWKFQLHPSVFSVITESVLQIISYTDTSDLEAKTMALQHCKPQ
IMDFDPRKEIDNLYTEEIELNLKLQTFIFNCSQLIAGQNTVKAQIKANLR
KQYVNLLDQNALPLNLEYQNHLKCFINNSYQKGEIRRYKLVDILIRQLEI
SGSVERNGKRHTKLDRNSFSKTIKRLDQDALDLRSLQILRGLIYNEECLL
PDNWELKIFNSSVQDILKCIKNVQNCLNKLNLSSRTQIHMVNSCDLVKRE
AITLQSAMLMNANKNVQESLLRYFKGAQEEVFFSAIKYQLQNAFTDLKDQ
KLMLSQKKSFGDIEKYTCHESDLRIDNLAHILYQQLAEYEIRYEDQNRSL
AINRYAYTTTKESFTTRHMRQIYTPAKMKSEINSSSPLICCPRNSSKSNY
DMRSTDKSDSLFKNNLQDEYELKSVVTKESNSSTDKTIENSAWIKGETLD
LMRNDPHQNVKLILQLLSRMCVGQYQGLQNYLRIQPDNRSSVDVISLIVQ
FLGNIYANVRQSTIDLSIQAFDTIKETIMGNQENRSVVYRAKVVDYANFI
LRNDEISETCDPNNVLQMFLVIGRVIMALIEENGREETELAKEIQITLDI
KAVFKIMTRCLDMMEDTKRKLIKNKIYDVGFTYFLILARLEDLCNGKLLK
HFQISDQQMKAFKFFKKGSASVEILKGDQLQRIHFRLKHKEVLRESVKEK
VKWEVDRTTPSNKIRSFISWSKLILPDMNFQRKIIQNPLLLFVTKQWNAM
NYFLTLLSLVINILY*
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protein sequence of SMED30018386-orf-2

>SMED30018386-orf-2 ID=SMED30018386-orf-2|Name=SMED30018386-orf-2|organism=Schmidtea mediterranea sexual|type=polypeptide|length=194bp
MVKTYSAGYEFSEENHSKSSFAICYQTMECHELFPYIAQSCYKYTLLIGV
KAPDKGYINLTGPISPRHSDFDNYTIIWKPQYVIFREVVMGLGVSHAVIA
FLILITYLITDRPTLRTIRSYASRIKQRMVSFYKKEDENDSEKMVDGTNQ
LVSLFSFMRFLYCCPCQSVESGYLTCTCFTCSTSFTTTNCLKV*
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protein sequence of SMED30018386-orf-3

>SMED30018386-orf-3 ID=SMED30018386-orf-3|Name=SMED30018386-orf-3|organism=Schmidtea mediterranea sexual|type=polypeptide|length=359bp
MSIGGIWIPYLYVFHLFNVIHNNQLLKGVIASVTKNGRVLIWVMILMVIV
MYIFSIFAFCFLRSTFSSENYLYADTLVQTFVSLVRFGIVGDLYQYTIPH
KYYMKTVDTAFTEFSLILIFQLFFFIFITITGLNIIFGIIVDTFSELRDL
KYKTEKDMKETCFICSRAGHDFDQSSSSFEHHVVYEHNMWAYLFYFLHLK
EIKINDYFHLDLYVANMLKRENYDFFPINCALSLTAEQEKYSRIDEISRN
VKIIVSNRQNEEREKLRRTNLFKQSQWQKQYQNSQVSSGSYQDLNVDEIN
FDGHSNEIERSPSLHERHLSVHSSLEIQPPSQTRFKSPTSTPSPGTKRNL
LSLSTSSK*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: cellular component
TermDefinition
GO:0016021integral component of membrane
GO:0016020membrane
GO:0005737cytoplasm
GO:0005783endoplasmic reticulum
Vocabulary: molecular function
TermDefinition
GO:0070679inositol 1,4,5 trisphosphate binding
GO:0005216ion channel activity
GO:0005262calcium channel activity
GO:0005220inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000016pharynx
PLANA:0000020protonephridia
PLANA:0000099neuron
PLANA:0000420parapharyngeal region
PLANA:0003116parenchymal cell
Vocabulary: INTERPRO
TermDefinition
IPR036300MIR_dom_sf
IPR035910RyR/IP3R_RIH_dom_sf
IPR005821Ion_trans_dom
IPR000699RIH_dom
IPR013662RIH_assoc-dom
IPR016093MIR_motif
IPR014821Ins145_P3_rcpt
IPR006588Peptide_N_glycanase_PAW_dom
Vocabulary: biological process
TermDefinition
GO:0006811ion transport
GO:0055085transmembrane transport
GO:0070588calcium ion transmembrane transport
GO:0006516glycoprotein catabolic process
GO:0006816calcium ion transport
GO:0048016inositol phosphate-mediated signaling
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 67..94
NoneNo IPR availableGENE3DG3DSA:2.80.10.50coord: 230..403
e-value: 5.6E-28
score: 100.0
NoneNo IPR availableGENE3DG3DSA:2.80.10.50coord: 1..227
e-value: 1.1E-43
score: 151.2
NoneNo IPR availablePANTHERPTHR13715RYANODINE RECEPTOR AND IP3 RECEPTORcoord: 31..2216
NoneNo IPR availablePANTHERPTHR13715:SF99INOSITOL 1,4,5-TRISPHOSPHATE RECEPTOR-LIKE PROTEIN Acoord: 31..2216
IPR013662RyR/IP3R Homology associated domainPFAMPF08454RIH_assoccoord: 1909..2001
e-value: 3.0E-17
score: 62.3
IPR014821Inositol 1,4,5-trisphosphate/ryanodine receptorPFAMPF08709Ins145_P3_reccoord: 3..219
e-value: 3.8E-23
score: 81.8
IPR016093MIR motifPFAMPF02815MIRcoord: 237..385
e-value: 1.5E-7
score: 31.4
IPR016093MIR motifPROSITEPS50919MIRcoord: 357..420
score: 6.596
IPR016093MIR motifPROSITEPS50919MIRcoord: 236..301
score: 7.452
IPR016093MIR motifPROSITEPS50919MIRcoord: 113..167
score: 9.557
IPR000699RIH domainPFAMPF01365RYDR_ITPRcoord: 491..629
e-value: 1.2E-11
score: 44.4
IPR036300Mir domain superfamilySUPERFAMILYSSF82109MIR domaincoord: 241..385
IPR036300Mir domain superfamilySUPERFAMILYSSF82109MIR domaincoord: 110..176
IPR035910RyR/IP3 receptor binding core, RIH domain superfamilySUPERFAMILYSSF100909IP3 receptor type 1 binding core, domain 2coord: 482..579