Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30018369 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 9
Homology
BLAST of Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN vs. Ensembl Human
Match: PTEN (phosphatase and tensin homolog [Source:HGNC Symbol;Acc:HGNC:9588]) HSP 1 Score: 245.743 bits (626), Expect = 2.806e-75 Identity = 141/361 (39.06%), Postives = 207/361 (57.34%), Query Frame = 2
Query: 68 MNSTIRTIVSKKKRRYKKQGFNLDLSYVTSRIIAMGFPAEKFEALYRNDIDDVSKFFEVNHCGKYKIYNLCRERNFNASKFSGEIARFPFDDHNAPIFTDLVACVNDIAQFLDSCPDNVVAINCKAGKGRTGVIVCCTLIHCENNKDATTALQDYGKSRTLNGKGVTIPSQIRYIFYYDHFVKNKLKYASIPLWLRKINFEMVPNIGNAEVEYAIYRVNSQNKIXXXXXXXXXXQDRQITFVESISYPLEDDLKFQFFYK-TLMGGTKILCQCWLNTFFIVNQPLIQCLDPVPRKSNSKNVFNRLPSKPPSDEAKCPIARPEKPHENIYTIRLTKKEIDEANKDSTFRIFPENFSITFMFS 1147
M + I+ IVS+ KRRY++ GF+LDL+Y+ IIAMGFPAE+ E +YRN+IDDV +F + H YKIYNLC ER+++ +KF+ +A++PF+DHN P + D+ Q+L ++V AI+CKAGKGRTGV++C L+H A AL YG+ RT + KGVTIPSQ RY++YY + +KN L Y + L K+ FE +P + KIYSS + T ++D+ + F P+ D+K +FF+K M + W+NTFFI P P +++ K L + ++ C I R + E + + LTK ++D+ANKD R F NF + F+
Sbjct: 1 MTAIIKEIVSRNKRRYQEDGFDLDLTYIYPNIIAMGFPAERLEGVYRNNIDDVVRFLDSKHKNHYKIYNLCAERHYDTAKFNCRVAQYPFEDHNPPQLELIKPFCEDLDQWLSEDDNHVAAIHCKAGKGRTGVMICAYLLHRGKFLKAQEALDFYGEVRTRDKKGVTIPSQRRYVYYYSYLLKNHLDYRPVALLFHKMMFETIPMFSGGTCNPQFVVCQLKVKIYSSNSGPTRREDKFMYFEFPQPLPVCGDIKVEFFHKQNKMLKKDKMFHFWVNTFFI----------PGPEETSEKVENGSLCDQ--EIDSICSIERADNDKEYL-VLTLTKNDLDKANKDKANRYFSPNFKVKLYFT 348
BLAST of Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN vs. Ensembl Human
Match: PTEN (phosphatase and tensin homolog [Source:HGNC Symbol;Acc:HGNC:9588]) HSP 1 Score: 245.358 bits (625), Expect = 2.895e-73 Identity = 141/361 (39.06%), Postives = 207/361 (57.34%), Query Frame = 2
Query: 68 MNSTIRTIVSKKKRRYKKQGFNLDLSYVTSRIIAMGFPAEKFEALYRNDIDDVSKFFEVNHCGKYKIYNLCRERNFNASKFSGEIARFPFDDHNAPIFTDLVACVNDIAQFLDSCPDNVVAINCKAGKGRTGVIVCCTLIHCENNKDATTALQDYGKSRTLNGKGVTIPSQIRYIFYYDHFVKNKLKYASIPLWLRKINFEMVPNIGNAEVEYAIYRVNSQNKIXXXXXXXXXXQDRQITFVESISYPLEDDLKFQFFYKT-LMGGTKILCQCWLNTFFIVNQPLIQCLDPVPRKSNSKNVFNRLPSKPPSDEAKCPIARPEKPHENIYTIRLTKKEIDEANKDSTFRIFPENFSITFMFS 1147
M + I+ IVS+ KRRY++ GF+LDL+Y+ IIAMGFPAE+ E +YRN+IDDV +F + H YKIYNLC ER+++ +KF+ +A++PF+DHN P + D+ Q+L ++V AI+CKAGKGRTGV++C L+H A AL YG+ RT + KGVTIPSQ RY++YY + +KN L Y + L K+ FE +P + KIYSS + T ++D+ + F P+ D+K +FF+K M + W+NTFFI P P +++ K L + ++ C I R + E + + LTK ++D+ANKD R F NF + F+
Sbjct: 174 MTAIIKEIVSRNKRRYQEDGFDLDLTYIYPNIIAMGFPAERLEGVYRNNIDDVVRFLDSKHKNHYKIYNLCAERHYDTAKFNCRVAQYPFEDHNPPQLELIKPFCEDLDQWLSEDDNHVAAIHCKAGKGRTGVMICAYLLHRGKFLKAQEALDFYGEVRTRDKKGVTIPSQRRYVYYYSYLLKNHLDYRPVALLFHKMMFETIPMFSGGTCNPQFVVCQLKVKIYSSNSGPTRREDKFMYFEFPQPLPVCGDIKVEFFHKQNKMLKKDKMFHFWVNTFFI----------PGPEETSEKVENGSLCDQ--EIDSICSIERADNDKEYL-VLTLTKNDLDKANKDKANRYFSPNFKVKLYFT 521
BLAST of Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN vs. Ensembl Human
Match: PTEN (phosphatase and tensin homolog [Source:HGNC Symbol;Acc:HGNC:9588]) HSP 1 Score: 245.358 bits (625), Expect = 2.895e-73 Identity = 141/361 (39.06%), Postives = 207/361 (57.34%), Query Frame = 2
Query: 68 MNSTIRTIVSKKKRRYKKQGFNLDLSYVTSRIIAMGFPAEKFEALYRNDIDDVSKFFEVNHCGKYKIYNLCRERNFNASKFSGEIARFPFDDHNAPIFTDLVACVNDIAQFLDSCPDNVVAINCKAGKGRTGVIVCCTLIHCENNKDATTALQDYGKSRTLNGKGVTIPSQIRYIFYYDHFVKNKLKYASIPLWLRKINFEMVPNIGNAEVEYAIYRVNSQNKIXXXXXXXXXXQDRQITFVESISYPLEDDLKFQFFYKT-LMGGTKILCQCWLNTFFIVNQPLIQCLDPVPRKSNSKNVFNRLPSKPPSDEAKCPIARPEKPHENIYTIRLTKKEIDEANKDSTFRIFPENFSITFMFS 1147
M + I+ IVS+ KRRY++ GF+LDL+Y+ IIAMGFPAE+ E +YRN+IDDV +F + H YKIYNLC ER+++ +KF+ +A++PF+DHN P + D+ Q+L ++V AI+CKAGKGRTGV++C L+H A AL YG+ RT + KGVTIPSQ RY++YY + +KN L Y + L K+ FE +P + KIYSS + T ++D+ + F P+ D+K +FF+K M + W+NTFFI P P +++ K L + ++ C I R + E + + LTK ++D+ANKD R F NF + F+
Sbjct: 174 MTAIIKEIVSRNKRRYQEDGFDLDLTYIYPNIIAMGFPAERLEGVYRNNIDDVVRFLDSKHKNHYKIYNLCAERHYDTAKFNCRVAQYPFEDHNPPQLELIKPFCEDLDQWLSEDDNHVAAIHCKAGKGRTGVMICAYLLHRGKFLKAQEALDFYGEVRTRDKKGVTIPSQRRYVYYYSYLLKNHLDYRPVALLFHKMMFETIPMFSGGTCNPQFVVCQLKVKIYSSNSGPTRREDKFMYFEFPQPLPVCGDIKVEFFHKQNKMLKKDKMFHFWVNTFFI----------PGPEETSEKVENGSLCDQ--EIDSICSIERADNDKEYL-VLTLTKNDLDKANKDKANRYFSPNFKVKLYFT 521
BLAST of Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN vs. Ensembl Human
Match: TPTE2 (transmembrane phosphoinositide 3-phosphatase and tensin homolog 2 [Source:HGNC Symbol;Acc:HGNC:17299]) HSP 1 Score: 163.696 bits (413), Expect = 2.427e-44 Identity = 104/302 (34.44%), Postives = 156/302 (51.66%), Query Frame = 2
Query: 68 MNSTIRTIVSKKKRRYKKQGFNLDLSYVTSRIIAMGFPAEKFEALYRNDIDDVSKFFEVNHCGKYKIYNLCRERNFNASKFSGEIARFPFDDHNAPIFTDLVACVNDIAQFLDSCPDNVVAINCKAGKGRTGVIVCCTLIHCENNKDATTALQDYGKSRTLNG-----KGVTIPSQIRYIFYY---DHFVKNKLKYASIPLWLRKINFEMVPNIGNAEVEYAIYR--VNSQNKIXXXXXXXXXXQDRQITFVESISYPLEDDLKFQFFYKTLMGGTKILCQC----WLNTFFIVNQPLIQCL 931
+ +R +VS+ KRRY + GF+LDL+YVT RIIAM FP+ ++ YRN I++V +F + H Y++YNLC ER ++ F ++R DDHN P ++V ++ +++ +N+VAI+CK GKGRTG +VC LI E A +L +G+ RT +GV PSQ RY+ Y+ H L I R I + + ++ + +V+ + + V S + + + D+ + V PL DD+K QFF L K C W NT FI N L CL
Sbjct: 86 LEKLMRRLVSENKRRYTRDGFDLDLTYVTERIIAMSFPSSGRQSFYRNPIEEVVRFLDKKHRNHYRVYNLCSERAYDPKHFHNRVSRIMIDDHNVPTLHEMVVFTKEVNEWMAQDLENIVAIHCKGGKGRTGTMVCALLIASEIFLTAEESLYYFGERRTNKTHSNKFQGVETPSQNRYVGYFAQVKHLYNWNLPPRRILFIKRFIIYSIRGDVCDLKVQVVMEKKVVFSSTSLGNCSILHDIETDKILINVYD-GPPLYDDVKVQFFSSNL---PKYYDNCPFFFWFNTSFIQNNRL--CL 381
BLAST of Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN vs. Ensembl Human
Match: TPTE2 (transmembrane phosphoinositide 3-phosphatase and tensin homolog 2 [Source:HGNC Symbol;Acc:HGNC:17299]) HSP 1 Score: 162.925 bits (411), Expect = 7.891e-44 Identity = 104/302 (34.44%), Postives = 156/302 (51.66%), Query Frame = 2
Query: 68 MNSTIRTIVSKKKRRYKKQGFNLDLSYVTSRIIAMGFPAEKFEALYRNDIDDVSKFFEVNHCGKYKIYNLCRERNFNASKFSGEIARFPFDDHNAPIFTDLVACVNDIAQFLDSCPDNVVAINCKAGKGRTGVIVCCTLIHCENNKDATTALQDYGKSRTLNG-----KGVTIPSQIRYIFYY---DHFVKNKLKYASIPLWLRKINFEMVPNIGNAEVEYAIYR--VNSQNKIXXXXXXXXXXQDRQITFVESISYPLEDDLKFQFFYKTLMGGTKILCQC----WLNTFFIVNQPLIQCL 931
+ +R +VS+ KRRY + GF+LDL+YVT RIIAM FP+ ++ YRN I++V +F + H Y++YNLC ER ++ F ++R DDHN P ++V ++ +++ +N+VAI+CK GKGRTG +VC LI E A +L +G+ RT +GV PSQ RY+ Y+ H L I R I + + ++ + +V+ + + V S + + + D+ + V PL DD+K QFF L K C W NT FI N L CL
Sbjct: 120 LEKLMRRLVSENKRRYTRDGFDLDLTYVTERIIAMSFPSSGRQSFYRNPIEEVVRFLDKKHRNHYRVYNLCSERAYDPKHFHNRVSRIMIDDHNVPTLHEMVVFTKEVNEWMAQDLENIVAIHCKGGKGRTGTMVCALLIASEIFLTAEESLYYFGERRTNKTHSNKFQGVETPSQNRYVGYFAQVKHLYNWNLPPRRILFIKRFIIYSIRGDVCDLKVQVVMEKKVVFSSTSLGNCSILHDIETDKILINVYD-GPPLYDDVKVQFFSSNL---PKYYDNCPFFFWFNTSFIQNNRL--CL 415
BLAST of Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN vs. Ensembl Celegans
Match: daf-18 (Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase daf-18 [Source:UniProtKB/Swiss-Prot;Acc:G5EE01]) HSP 1 Score: 131.724 bits (330), Expect = 5.874e-32 Identity = 73/200 (36.50%), Postives = 107/200 (53.50%), Query Frame = 2
Query: 83 RTIVSKKKRRYKKQGFNLDLSYVTSRIIAMGFPAEKFEALYRNDIDDVSKFFEVNHC-GKYKIYNLCRERNFNASKFSGEIARFPFDDHNAPIFTDLVACVNDIAQFLDSCPDNVVAINCKAGKGRTGVIVCCTLIHCENNKDATTALQDYGKSRTLNGKGVTIPSQIRYIFYYDHFVKNKLKYASIPLWLRKINFEMVP 679
RT VS + R + Q +LD +Y+T RIIA+G+PA EA +RN +F H G K++NL ++A F G + F DH+ P + + ++L++ +V+A++CKAGKGRTGV++C LI+ L Y RT N KGVTIPSQ RYI+YY + +L Y + + L + E P
Sbjct: 50 RTAVSSNRCRTEYQNIDLDCAYITDRIIAIGYPATGIEANFRNSKVQTQQFLTRRHGKGNVKVFNLRGGYYYDADNFDGNVICFDMTDHHPPSLELMAPFCREAKEWLEADDKHVIAVHCKAGKGRTGVMICALLIYINFYPSPRQILDYYSIIRTKNNKGVTIPSQRRYIYYYHKLRERELNYLPLRMQLIGVYVERPP 249
BLAST of Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN vs. Ensembl Celegans
Match: tns-1 (TeNSin homolog [Source:UniProtKB/TrEMBL;Acc:H2L045]) HSP 1 Score: 56.9954 bits (136), Expect = 3.687e-8 Identity = 44/193 (22.80%), Postives = 88/193 (45.60%), Query Frame = 2
Query: 98 KKKRRYKKQGFNLDLSYVTSRIIAMGFPAEKFEALYRNDIDDVSKFFEVNHCGKYKIYNLCRERNFNASKFSGEIARFPFDDHNAPIFTDLVACVNDIAQFLDSCPDNVVAINCKAGKGRTGVIVCC-----TLIHCENNKDATTALQDYGKSRTLNGKGVTIPSQIRYIFYYDHFVKNKLKYASIPLWLRKI 661
K+K + +K+G ++ Y+TSR+I + +E E + + S+ + H +++N+ + R+ +S + F + AP L ++ Q++ P N+ I CK G R ++V + +++ D ++Q + + R L G PS RY+ Y+ + ++ S PL+L I
Sbjct: 35 KQKMKDRKEGVQVE--YITSRLIVLSCTSETSERKFVESLLKASQQIQNAHNKHIRVWNVSQRRHDISSSL--DAIPFGWPSETAPSLEKLCTICKNLDQWMLEHPLNIAVIFCKGGLERCAIVVNAFMRFNAISATDDSVDDRFSMQRFSE-RFLGPDGP--PSYKRYLGYFSSLLSGRISVNSDPLYLHNI 220
BLAST of Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN vs. Ensembl Celegans
Match: tns-1 (TeNSin homolog [Source:UniProtKB/TrEMBL;Acc:H2L045]) HSP 1 Score: 53.9138 bits (128), Expect = 3.049e-7 Identity = 42/187 (22.46%), Postives = 84/187 (44.92%), Query Frame = 2
Query: 116 KKQGFNLDLSYVTSRIIAMGFPAEKFEALYRNDIDDVSKFFEVNHCGKYKIYNLCRERNFNASKFSGEIARFPFDDHNAPIFTDLVACVNDIAQFLDSCPDNVVAINCKAGKGRTGVIVCC-----TLIHCENNKDATTALQDYGKSRTLNGKGVTIPSQIRYIFYYDHFVKNKLKYASIPLWLRKI 661
+K+G ++ Y+TSR+I + +E E + + S+ + H +++N+ + R+ +S + F + AP L ++ Q++ P N+ I CK G R ++V + +++ D ++Q + + R L G PS RY+ Y+ + ++ S PL+L I
Sbjct: 4 RKEGVQVE--YITSRLIVLSCTSETSERKFVESLLKASQQIQNAHNKHIRVWNVSQRRHDISSSL--DAIPFGWPSETAPSLEKLCTICKNLDQWMLEHPLNIAVIFCKGGLERCAIVVNAFMRFNAISATDDSVDDRFSMQRFSE-RFLGPDGP--PSYKRYLGYFSSLLSGRISVNSDPLYLHNI 183
BLAST of Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN vs. Ensembl Fly
Match: Pten (gene:FBgn0026379 transcript:FBtr0089902) HSP 1 Score: 223.402 bits (568), Expect = 5.590e-67 Identity = 137/365 (37.53%), Postives = 197/365 (53.97%), Query Frame = 2
Query: 68 MNSTIRTIVSKKKRRYKKQGFNLDLSYVTSRIIAMGFPA-EKFEALYRNDIDDVSKFFEVNHCGKYKIYNLCRERNFNASKFSGEIARFPFDDHNAPIFTDLVACVNDIAQFLDSCPDNVVAINCKAGKGRTGVIVCCTLIHCENNKDATTALQDYGKSRTLNGKGVTIPSQIRYIFYYDHFVKNKLKYASIPLWLRKINF---EMVPNIGNAEVEYAIYRVNSQNKIXXXXXXXXXXQDRQITFVESI--SYPLEDDLKFQFFYKTLMGGTKILCQCWLNTFFIVNQPLIQCLDPVPRKSNSKNVFNRLPSKPPSDEAKCPIARPEKPHENIYTIRLTKKEIDEANKDSTFRIFPENFSITFMF 1144
M++ IR +VSKK+ RYK++G++LDL+Y+ IIAMG+PA +K E L+RN ++DV K E NH YKIYNLC ER+++ +KF G +A +PFDDHN P + +D+ +L NVVA++CKAGKGRTG ++C L+ K A AL Y + RT + KGVTIPSQ RY+ Y+ V + + Y+ + L + +I F V N+G E ++ +S + KT D Q +FV +I S P+ D+KF+ K+ KI+C WLNTFF+ N + V N Y L+K EID+ +KDS + F E F I+ +F
Sbjct: 8 MSNVIRNVVSKKRIRYKEKGYDLDLTYINDNIIAMGYPAPDKLEGLFRNRLEDVFKLLEENHAQHYKIYNLCSERSYDVAKFRGRVAVYPFDDHNPPTIELIQRFCSDVDMWLKEDSSNVVAVHCKAGKGRTGTMICAYLVFSGIKKSADEALAWYDEKRTKDRKGVTIPSQRRYVQYFSKLVCSSVPYSKVSLNVCEIRFSESSCVQNLGMVECSISVLH-DSATENAKPDRLKTLPIDFQKSFVLTIKPSIPVSGDVKFELTKKS---PDKIICHFWLNTFFVRNYSPCESDGTV----------------------------------NKYIHTLSKSEIDDVHKDSEHKRFSEEFKISIVF 334
BLAST of Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN vs. Ensembl Fly
Match: Pten (gene:FBgn0026379 transcript:FBtr0300562) HSP 1 Score: 223.787 bits (569), Expect = 3.761e-66 Identity = 137/365 (37.53%), Postives = 197/365 (53.97%), Query Frame = 2
Query: 68 MNSTIRTIVSKKKRRYKKQGFNLDLSYVTSRIIAMGFPA-EKFEALYRNDIDDVSKFFEVNHCGKYKIYNLCRERNFNASKFSGEIARFPFDDHNAPIFTDLVACVNDIAQFLDSCPDNVVAINCKAGKGRTGVIVCCTLIHCENNKDATTALQDYGKSRTLNGKGVTIPSQIRYIFYYDHFVKNKLKYASIPLWLRKINFEM---VPNIGNAEVEYAIYRVNSQNKIXXXXXXXXXXQDRQITFVESI--SYPLEDDLKFQFFYKTLMGGTKILCQCWLNTFFIVNQPLIQCLDPVPRKSNSKNVFNRLPSKPPSDEAKCPIARPEKPHENIYTIRLTKKEIDEANKDSTFRIFPENFSITFMF 1144
M++ IR +VSKK+ RYK++G++LDL+Y+ IIAMG+PA +K E L+RN ++DV K E NH YKIYNLC ER+++ +KF G +A +PFDDHN P + +D+ +L NVVA++CKAGKGRTG ++C L+ K A AL Y + RT + KGVTIPSQ RY+ Y+ V + + Y+ + L + +I F V N+G E ++ +S + KT D Q +FV +I S P+ D+KF+ K+ KI+C WLNTFF+ N + V N Y L+K EID+ +KDS + F E F I+ +F
Sbjct: 8 MSNVIRNVVSKKRIRYKEKGYDLDLTYINDNIIAMGYPAPDKLEGLFRNRLEDVFKLLEENHAQHYKIYNLCSERSYDVAKFRGRVAVYPFDDHNPPTIELIQRFCSDVDMWLKEDSSNVVAVHCKAGKGRTGTMICAYLVFSGIKKSADEALAWYDEKRTKDRKGVTIPSQRRYVQYFSKLVCSSVPYSKVSLNVCEIRFSESSCVQNLGMVECSISVLH-DSATENAKPDRLKTLPIDFQKSFVLTIKPSIPVSGDVKFELTKKS---PDKIICHFWLNTFFVRNYSPCESDGTV----------------------------------NKYIHTLSKSEIDDVHKDSEHKRFSEEFKISIVF 334
BLAST of Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN vs. Ensembl Fly
Match: Pten (gene:FBgn0026379 transcript:FBtr0301521) HSP 1 Score: 223.787 bits (569), Expect = 3.761e-66 Identity = 137/365 (37.53%), Postives = 197/365 (53.97%), Query Frame = 2
Query: 68 MNSTIRTIVSKKKRRYKKQGFNLDLSYVTSRIIAMGFPA-EKFEALYRNDIDDVSKFFEVNHCGKYKIYNLCRERNFNASKFSGEIARFPFDDHNAPIFTDLVACVNDIAQFLDSCPDNVVAINCKAGKGRTGVIVCCTLIHCENNKDATTALQDYGKSRTLNGKGVTIPSQIRYIFYYDHFVKNKLKYASIPLWLRKINFEM---VPNIGNAEVEYAIYRVNSQNKIXXXXXXXXXXQDRQITFVESI--SYPLEDDLKFQFFYKTLMGGTKILCQCWLNTFFIVNQPLIQCLDPVPRKSNSKNVFNRLPSKPPSDEAKCPIARPEKPHENIYTIRLTKKEIDEANKDSTFRIFPENFSITFMF 1144
M++ IR +VSKK+ RYK++G++LDL+Y+ IIAMG+PA +K E L+RN ++DV K E NH YKIYNLC ER+++ +KF G +A +PFDDHN P + +D+ +L NVVA++CKAGKGRTG ++C L+ K A AL Y + RT + KGVTIPSQ RY+ Y+ V + + Y+ + L + +I F V N+G E ++ +S + KT D Q +FV +I S P+ D+KF+ K+ KI+C WLNTFF+ N + V N Y L+K EID+ +KDS + F E F I+ +F
Sbjct: 8 MSNVIRNVVSKKRIRYKEKGYDLDLTYINDNIIAMGYPAPDKLEGLFRNRLEDVFKLLEENHAQHYKIYNLCSERSYDVAKFRGRVAVYPFDDHNPPTIELIQRFCSDVDMWLKEDSSNVVAVHCKAGKGRTGTMICAYLVFSGIKKSADEALAWYDEKRTKDRKGVTIPSQRRYVQYFSKLVCSSVPYSKVSLNVCEIRFSESSCVQNLGMVECSISVLH-DSATENAKPDRLKTLPIDFQKSFVLTIKPSIPVSGDVKFELTKKS---PDKIICHFWLNTFFVRNYSPCESDGTV----------------------------------NKYIHTLSKSEIDDVHKDSEHKRFSEEFKISIVF 334
BLAST of Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN vs. Ensembl Fly
Match: Pten (gene:FBgn0026379 transcript:FBtr0089900) HSP 1 Score: 223.787 bits (569), Expect = 3.761e-66 Identity = 137/365 (37.53%), Postives = 197/365 (53.97%), Query Frame = 2
Query: 68 MNSTIRTIVSKKKRRYKKQGFNLDLSYVTSRIIAMGFPA-EKFEALYRNDIDDVSKFFEVNHCGKYKIYNLCRERNFNASKFSGEIARFPFDDHNAPIFTDLVACVNDIAQFLDSCPDNVVAINCKAGKGRTGVIVCCTLIHCENNKDATTALQDYGKSRTLNGKGVTIPSQIRYIFYYDHFVKNKLKYASIPLWLRKINFEM---VPNIGNAEVEYAIYRVNSQNKIXXXXXXXXXXQDRQITFVESI--SYPLEDDLKFQFFYKTLMGGTKILCQCWLNTFFIVNQPLIQCLDPVPRKSNSKNVFNRLPSKPPSDEAKCPIARPEKPHENIYTIRLTKKEIDEANKDSTFRIFPENFSITFMF 1144
M++ IR +VSKK+ RYK++G++LDL+Y+ IIAMG+PA +K E L+RN ++DV K E NH YKIYNLC ER+++ +KF G +A +PFDDHN P + +D+ +L NVVA++CKAGKGRTG ++C L+ K A AL Y + RT + KGVTIPSQ RY+ Y+ V + + Y+ + L + +I F V N+G E ++ +S + KT D Q +FV +I S P+ D+KF+ K+ KI+C WLNTFF+ N + V N Y L+K EID+ +KDS + F E F I+ +F
Sbjct: 8 MSNVIRNVVSKKRIRYKEKGYDLDLTYINDNIIAMGYPAPDKLEGLFRNRLEDVFKLLEENHAQHYKIYNLCSERSYDVAKFRGRVAVYPFDDHNPPTIELIQRFCSDVDMWLKEDSSNVVAVHCKAGKGRTGTMICAYLVFSGIKKSADEALAWYDEKRTKDRKGVTIPSQRRYVQYFSKLVCSSVPYSKVSLNVCEIRFSESSCVQNLGMVECSISVLH-DSATENAKPDRLKTLPIDFQKSFVLTIKPSIPVSGDVKFELTKKS---PDKIICHFWLNTFFVRNYSPCESDGTV----------------------------------NKYIHTLSKSEIDDVHKDSEHKRFSEEFKISIVF 334
BLAST of Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN vs. Ensembl Fly
Match: Pten (gene:FBgn0026379 transcript:FBtr0089904) HSP 1 Score: 223.787 bits (569), Expect = 3.761e-66 Identity = 137/365 (37.53%), Postives = 197/365 (53.97%), Query Frame = 2
Query: 68 MNSTIRTIVSKKKRRYKKQGFNLDLSYVTSRIIAMGFPA-EKFEALYRNDIDDVSKFFEVNHCGKYKIYNLCRERNFNASKFSGEIARFPFDDHNAPIFTDLVACVNDIAQFLDSCPDNVVAINCKAGKGRTGVIVCCTLIHCENNKDATTALQDYGKSRTLNGKGVTIPSQIRYIFYYDHFVKNKLKYASIPLWLRKINFEM---VPNIGNAEVEYAIYRVNSQNKIXXXXXXXXXXQDRQITFVESI--SYPLEDDLKFQFFYKTLMGGTKILCQCWLNTFFIVNQPLIQCLDPVPRKSNSKNVFNRLPSKPPSDEAKCPIARPEKPHENIYTIRLTKKEIDEANKDSTFRIFPENFSITFMF 1144
M++ IR +VSKK+ RYK++G++LDL+Y+ IIAMG+PA +K E L+RN ++DV K E NH YKIYNLC ER+++ +KF G +A +PFDDHN P + +D+ +L NVVA++CKAGKGRTG ++C L+ K A AL Y + RT + KGVTIPSQ RY+ Y+ V + + Y+ + L + +I F V N+G E ++ +S + KT D Q +FV +I S P+ D+KF+ K+ KI+C WLNTFF+ N + V N Y L+K EID+ +KDS + F E F I+ +F
Sbjct: 8 MSNVIRNVVSKKRIRYKEKGYDLDLTYINDNIIAMGYPAPDKLEGLFRNRLEDVFKLLEENHAQHYKIYNLCSERSYDVAKFRGRVAVYPFDDHNPPTIELIQRFCSDVDMWLKEDSSNVVAVHCKAGKGRTGTMICAYLVFSGIKKSADEALAWYDEKRTKDRKGVTIPSQRRYVQYFSKLVCSSVPYSKVSLNVCEIRFSESSCVQNLGMVECSISVLH-DSATENAKPDRLKTLPIDFQKSFVLTIKPSIPVSGDVKFELTKKS---PDKIICHFWLNTFFVRNYSPCESDGTV----------------------------------NKYIHTLSKSEIDDVHKDSEHKRFSEEFKISIVF 334
BLAST of Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN vs. Ensembl Zebrafish
Match: ptena (phosphatase and tensin homolog A [Source:ZFIN;Acc:ZDB-GENE-030131-3776]) HSP 1 Score: 250.366 bits (638), Expect = 2.254e-77 Identity = 139/367 (37.87%), Postives = 214/367 (58.31%), Query Frame = 2
Query: 68 MNSTIRTIVSKKKRRYKKQGFNLDLSYVTSRIIAMGFPAEKFEALYRNDIDDVSKFFEVNHCGKYKIYNLCRERNFNASKFSGEIARFPFDDHNAPIFTDLVACVNDIAQFLDSCPDNVVAINCKAGKGRTGVIVCCTLIHCENNKDATTALQDYGKSRTLNGKGVTIPSQIRYIFYYDHFVKNKLKYASIPLWLRKINFEMVPNI--GNAEVEYAIYRVNSQNKIXXXXXXXXXXQDRQITFVESISYPLEDDLKFQFFYK-TLMGGTKILCQCWLNTFFIVNQPLIQCLDPVPRKSNSK----NVFNRLPSKPPSDEAKCPIARPEKPHENIYTIRLTKKEIDEANKDSTFRIFPENFSITFMFS 1147
M + ++ IVS+ KRRY++ GF+LDL+Y+ IIAMGFPAE+ E +YRN+IDDV +F + H YKIYNLC ER+++ASKF+ +A++PF+DHN P + D+ Q+L ++V AI+CKAGKGRTGV++C L+H + +A AL YG+ RT + KGVTIPSQ RY++YY + +KNKL Y + L K+ F+ +P G ++ +Y++ KI++S T ++++ + F P+ D+K +FF+K + M + W+NTFFI P P ++ K +V N + + E ++ + LTK ++D+ANKD R F NF + F+
Sbjct: 1 MTAKLKEIVSRNKRRYQEDGFDLDLTYIYPNIIAMGFPAERLEGVYRNNIDDVVRFLDSKHKNHYKIYNLCAERHYDASKFNCRVAQYPFEDHNPPQLELIKPFCEDLDQWLSEDENHVAAIHCKAGKGRTGVMICAYLLHRKKFAEAQEALDFYGEVRTRDKKGVTIPSQRRYVYYYSYLLKNKLDYKPVALLFHKMVFQTLPMFSGGTCNPQFVVYQLKV--KIHTSNPAHTRREEKHMIFEFPQPLPVCGDIKVEFFHKQSKMMKKDKMFHFWINTFFI----------PGPEEAGDKVENGSVVNDVDKQRADGE------------KDYLILTLTKNDLDKANKDKANRYFSPNFKVKLYFT 343
BLAST of Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN vs. Ensembl Zebrafish
Match: ptena (phosphatase and tensin homolog A [Source:ZFIN;Acc:ZDB-GENE-030131-3776]) HSP 1 Score: 250.366 bits (638), Expect = 2.254e-77 Identity = 139/367 (37.87%), Postives = 214/367 (58.31%), Query Frame = 2
Query: 68 MNSTIRTIVSKKKRRYKKQGFNLDLSYVTSRIIAMGFPAEKFEALYRNDIDDVSKFFEVNHCGKYKIYNLCRERNFNASKFSGEIARFPFDDHNAPIFTDLVACVNDIAQFLDSCPDNVVAINCKAGKGRTGVIVCCTLIHCENNKDATTALQDYGKSRTLNGKGVTIPSQIRYIFYYDHFVKNKLKYASIPLWLRKINFEMVPNI--GNAEVEYAIYRVNSQNKIXXXXXXXXXXQDRQITFVESISYPLEDDLKFQFFYK-TLMGGTKILCQCWLNTFFIVNQPLIQCLDPVPRKSNSK----NVFNRLPSKPPSDEAKCPIARPEKPHENIYTIRLTKKEIDEANKDSTFRIFPENFSITFMFS 1147
M + ++ IVS+ KRRY++ GF+LDL+Y+ IIAMGFPAE+ E +YRN+IDDV +F + H YKIYNLC ER+++ASKF+ +A++PF+DHN P + D+ Q+L ++V AI+CKAGKGRTGV++C L+H + +A AL YG+ RT + KGVTIPSQ RY++YY + +KNKL Y + L K+ F+ +P G ++ +Y++ KI++S T ++++ + F P+ D+K +FF+K + M + W+NTFFI P P ++ K +V N + + E ++ + LTK ++D+ANKD R F NF + F+
Sbjct: 1 MTAKLKEIVSRNKRRYQEDGFDLDLTYIYPNIIAMGFPAERLEGVYRNNIDDVVRFLDSKHKNHYKIYNLCAERHYDASKFNCRVAQYPFEDHNPPQLELIKPFCEDLDQWLSEDENHVAAIHCKAGKGRTGVMICAYLLHRKKFAEAQEALDFYGEVRTRDKKGVTIPSQRRYVYYYSYLLKNKLDYKPVALLFHKMVFQTLPMFSGGTCNPQFVVYQLKV--KIHTSNPAHTRREEKHMIFEFPQPLPVCGDIKVEFFHKQSKMMKKDKMFHFWINTFFI----------PGPEEAGDKVENGSVVNDVDKQRADGE------------KDYLILTLTKNDLDKANKDKANRYFSPNFKVKLYFT 343
BLAST of Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN vs. Ensembl Zebrafish
Match: ptena (phosphatase and tensin homolog A [Source:ZFIN;Acc:ZDB-GENE-030131-3776]) HSP 1 Score: 249.595 bits (636), Expect = 1.013e-76 Identity = 141/377 (37.40%), Postives = 219/377 (58.09%), Query Frame = 2
Query: 68 MNSTIRTIVSKKKRRYKKQGFNLDLSYVTSRIIAMGFPAEKFEALYRNDIDDVSKFFEVNHCGKYKIYNLCRERNFNASKFSGEIARFPFDDHNAPIFTDLVACVNDIAQFLDSCPDNVVAINCKAGKGRTGVIVCCTLIHCENNKDATTALQDYGKSRTLNGKGVTIPSQIRYIFYYDHFVKNKLKYASIPLWLRKINFEMVP--NIGNAEVEYAIYRVNSQNKIXXXXXXXXXXQDRQITFVESISYPLEDDLKFQFFYKT--LMGGTKILCQCWLNTFFI----------VNQPLIQCLDPVPRKSNSKNVFNRLPSKPPSDEAKCPIARPEK---PHENIYTIRLTKKEIDEANKDSTFRIFPENFSITFMFS 1147
M + ++ IVS+ KRRY++ GF+LDL+Y+ IIAMGFPAE+ E +YRN+IDDV +F + H YKIYNLC ER+++ASKF+ +A++PF+DHN P + D+ Q+L ++V AI+CKAGKGRTGV++C L+H + +A AL YG+ RT + KGVTIPSQ RY++YY + +KNKL Y + L K+ F+ +P + G ++ +Y++ KI++S T ++++ + F P+ D+K +FF+K +M K+ W+NTFFI N ++ +D + +S S + A R E+ ++ + LTK ++D+ANKD R F NF + F+
Sbjct: 3 MTAKLKEIVSRNKRRYQEDGFDLDLTYIYPNIIAMGFPAERLEGVYRNNIDDVVRFLDSKHKNHYKIYNLCAERHYDASKFNCRVAQYPFEDHNPPQLELIKPFCEDLDQWLSEDENHVAAIHCKAGKGRTGVMICAYLLHRKKFAEAQEALDFYGEVRTRDKKGVTIPSQRRYVYYYSYLLKNKLDYKPVALLFHKMVFQTLPMFSGGTCNPQFVVYQLKV--KIHTSNPAHTRREEKHMIFEFPQPLPVCGDIKVEFFHKQSKMMKKDKMF-HFWINTFFIPGPEEAGDKVENGSVVNDVDSLSCQSQSSPAERDREKERAVAAAALDRERGEQRADGEKDYLILTLTKNDLDKANKDKANRYFSPNFKVKLYFT 376
BLAST of Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN vs. Ensembl Zebrafish
Match: ptena (phosphatase and tensin homolog A [Source:ZFIN;Acc:ZDB-GENE-030131-3776]) HSP 1 Score: 244.588 bits (623), Expect = 1.292e-74 Identity = 140/389 (35.99%), Postives = 218/389 (56.04%), Query Frame = 2
Query: 68 MNSTIRTIVSKKKRRYKKQGFNLDLSYVTSRIIAMGFPAEKFEALYRNDIDDVSKFFEVNHCGKYKIYNLCRERNFNASKFSGEIARFPFDDHNAPIFTDLVACVNDIAQFLDSCPDNVVAINCKAGKGRTGVIVCCTLIHCENNKDATTALQDYGKSRTLNGKGVTIPSQIRYIFYYDHFVKNKLKYASIPLWLRKINFEMVP--NIGNAEVEYAIYRVNSQNKIXXXXXXXXXXQDRQITFVESISYPLEDDLKFQFFYKTLMGGTKI--------------LCQCWLNTFFI----------VNQPLIQCLDPVPRKSNSKNVFNRLPSKPPSDEAKCPIARPEK---PHENIYTIRLTKKEIDEANKDSTFRIFPENFSITFMFS 1147
M + ++ IVS+ KRRY++ GF+LDL+Y+ IIAMGFPAE+ E +YRN+IDDV +F + H YKIYNLC ER+++ASKF+ +A++PF+DHN P + D+ Q+L ++V AI+CKAGKGRTGV++C L+H + +A AL YG+ RT + KGVTIPSQ RY++YY + +KNKL Y + L K+ F+ +P + G ++ +Y++ KI++S T ++++ + F P+ D+K +FF+K K+ + W+NTFFI N ++ +D + +S S + A R E+ ++ + LTK ++D+ANKD R F NF + F+
Sbjct: 3 MTAKLKEIVSRNKRRYQEDGFDLDLTYIYPNIIAMGFPAERLEGVYRNNIDDVVRFLDSKHKNHYKIYNLCAERHYDASKFNCRVAQYPFEDHNPPQLELIKPFCEDLDQWLSEDENHVAAIHCKAGKGRTGVMICAYLLHRKKFAEAQEALDFYGEVRTRDKKGVTIPSQRRYVYYYSYLLKNKLDYKPVALLFHKMVFQTLPMFSGGTCNPQFVVYQLKV--KIHTSNPAHTRREEKHMIFEFPQPLPVCGDIKVEFFHKQSKMMKKVCLTRLDLLHKPLDKMFHFWINTFFIPGPEEAGDKVENGSVVNDVDSLSCQSQSSPAERDREKERAVAAAALDRERGEQRADGEKDYLILTLTKNDLDKANKDKANRYFSPNFKVKLYFT 389
BLAST of Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN vs. Ensembl Zebrafish
Match: ptena (phosphatase and tensin homolog A [Source:ZFIN;Acc:ZDB-GENE-030131-3776]) HSP 1 Score: 240.736 bits (613), Expect = 1.861e-73 Identity = 138/390 (35.38%), Postives = 214/390 (54.87%), Query Frame = 2
Query: 68 MNSTIRTIVSKKKRRYKKQGFNLDLSYVTSRIIAMGFPAEKFEALYRNDIDDVSKFFEVNHCGKYKIYNLCRERNFNASKFSGEIARFPFDDHNAPIFTDLVACVNDIAQFLDSCPDNVVAINCKAGKGRTGVIVCCTLIHCENNKDATTALQDYGKSRTLNGKGVTIPSQIRYIFYYDHFVKNKLKYASIPLWLRKINFEMVPNIGNA-------------------------EVEYAIYRVNSQNKIXXXXXXXXXXQDRQITFVESISYPLEDDLKFQFFYK-TLMGGTKILCQCWLNTFFIVNQPLIQCLDPVPRKSNSK----NVFNRLPSKPPSDEAKCPIARPEKPHENIYTIRLTKKEIDEANKDSTFRIFPENFSITFMFS 1147
M + ++ IVS+ KRRY++ GF+LDL+Y+ IIAMGFPAE+ E +YRN+IDDV +F + H YKIYNLC ER+++ASKF+ +A++PF+DHN P + D+ Q+L ++V AI+CKAGKGRTGV++C L+H + +A AL YG+ RT + KGVTIPSQ RY++YY + +KNKL Y + L K+ F+ +P + ++ +Y++ KI++S T ++++ + F P+ D+K +FF+K + M + W+NTFFI P P ++ K +V N + + E ++ + LTK ++D+ANKD R F NF + F+
Sbjct: 1 MTAKLKEIVSRNKRRYQEDGFDLDLTYIYPNIIAMGFPAERLEGVYRNNIDDVVRFLDSKHKNHYKIYNLCAERHYDASKFNCRVAQYPFEDHNPPQLELIKPFCEDLDQWLSEDENHVAAIHCKAGKGRTGVMICAYLLHRKKFAEAQEALDFYGEVRTRDKKGVTIPSQRRYVYYYSYLLKNKLDYKPVALLFHKMVFQTLPMFSGGTCRDSTVKNRSEVNPQGFKKGSWHWDPQFVVYQLKV--KIHTSNPAHTRREEKHMIFEFPQPLPVCGDIKVEFFHKQSKMMKKDKMFHFWINTFFI----------PGPEEAGDKVENGSVVNDVDKQRADGE------------KDYLILTLTKNDLDKANKDKANRYFSPNFKVKLYFT 366
BLAST of Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN vs. Ensembl Xenopus
Match: pten (phosphatase and tensin homolog [Source:NCBI gene;Acc:100144716]) HSP 1 Score: 243.047 bits (619), Expect = 2.581e-74 Identity = 141/365 (38.63%), Postives = 211/365 (57.81%), Query Frame = 2
Query: 68 MNSTIRTIVSKKKRRYKKQGFNLDLSYVTSRIIAMGFPAEKFEALYRNDIDDVSKFFEVNHCGKYKIYNLCRERNFNASKFSGEIARFPFDDHNAPIFTDLVACVNDIAQFLDSCPDNVVAINCKAGKGRTGVIVCCTLIHCENNKDATTALQDYGKSRTLNGKGVTIPSQIRYIFYYDHFVKNKLKYASIPLWLRKINFEMVPNIGNAEV--EYAIYRVNSQNKIXXXXXXXXXXQDRQITFVE-SISYPLEDDLKFQFFYKT--LMGGTKILCQCWLNTFFIVNQPLIQCLDPVPRKSNSKNVFNRLPSKPPSDEAKCPIARPEKPHENIYTIRLTKKEIDEANKDSTFRIFPENFSITFMFS 1147
M + I+ VS+ KRRY++ GF+LDL+Y+ IIAMGFPAE+ E +YRN+IDDV +F + H YKIYNLC ER+++ +KFS +A++PF+DHN P + D+ Q+L S +NV AI+CKAGKGRTGV++C L+H A AL YG+ RT + KGVTIPSQ RY++YY + +KN L+Y +PL KI FE +P + ++ +Y++ K+ + K+ ++ + + P+ D+K +FF+K +M K+ W+NTFFI P P + + K L + D R + E + T+ LTK ++D+ANKD R+F NF + F+
Sbjct: 1 MTAIIKEFVSRNKRRYQEDGFDLDLTYIYPNIIAMGFPAERLEGVYRNNIDDVVRFLDSKHKNHYKIYNLCAERHYDTNKFSCRVAQYPFEDHNPPQLELIKPFCEDLDQWL-SENENVAAIHCKAGKGRTGVMICAYLLHRGKFPRAQEALDFYGEVRTRDKKGVTIPSQRRYVYYYSYLLKNNLEYRPVPLLFHKIEFETIPMFSGSTCNPQFVVYQL----KVKIFTSTAGPKRIEKLMYFDFPQPLPVCGDIKVEFFHKQNKVMKKEKMF-HFWINTFFI----------PGPEEYSEKVENGTLVGEQELD-GIYSTERSDNDKEYL-TLTLTKNDLDKANKDKANRLFSPNFKVKLFFT 347
BLAST of Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN vs. Ensembl Xenopus
Match: pten (phosphatase and tensin homolog [Source:NCBI gene;Acc:100144716]) HSP 1 Score: 192.2 bits (487), Expect = 2.178e-55 Identity = 126/365 (34.52%), Postives = 188/365 (51.51%), Query Frame = 2
Query: 68 MNSTIRTIVSKKKRRYKKQGFNLDLSYVTSRIIAMGFPAEKFEALYRNDIDDVSKFFEVNHCGKYKIYNLCRERNFNASKFSGEIARFPFDDHNAPIFTDLVACVNDIAQFLDSCPDNVVAINCKAGKGRTGVIVCCTLIHCENNKDATTALQDYGKSRTLNGKGVTIPSQIRYIFYYDHFVKNKLKYASIPLWLRKINFEMVPNIGNAEV--EYAIYRVNSQNKIXXXXXXXXXXQDRQITFVE-SISYPLEDDLKFQFFYKT--LMGGTKILCQCWLNTFFIVNQPLIQCLDPVPRKSNSKNVFNRLPSKPPSDEAKCPIARPEKPHENIYTIRLTKKEIDEANKDSTFRIFPENFSITFMFS 1147
M + I+ VS+ KRRY++ GF+LDL+Y+ IIAMGFPAE+ E +YRN+IDDV +PF+DHN P + D+ Q+L S +NV AI+CKAGKGRTGV++C L+H A AL YG+ RT + KGVTIPSQ RY++YY + +KN L+Y +PL KI FE +P + ++ +Y++ K+ + K+ ++ + + P+ D+K +FF+K +M K+ W+NTFFI P P + + K L + D R + E + T+ LTK ++D+ANKD R+F NF + F+
Sbjct: 1 MTAIIKEFVSRNKRRYQEDGFDLDLTYIYPNIIAMGFPAERLEGVYRNNIDDV----------------------------------YPFEDHNPPQLELIKPFCEDLDQWL-SENENVAAIHCKAGKGRTGVMICAYLLHRGKFPRAQEALDFYGEVRTRDKKGVTIPSQRRYVYYYSYLLKNNLEYRPVPLLFHKIEFETIPMFSGSTCNPQFVVYQL----KVKIFTSTAGPKRIEKLMYFDFPQPLPVCGDIKVEFFHKQNKVMKKEKMF-HFWINTFFI----------PGPEEYSEKVENGTLVGEQELD-GIYSTERSDNDKEYL-TLTLTKNDLDKANKDKANRLFSPNFKVKLFFT 313
BLAST of Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN vs. Ensembl Xenopus
Match: tpte2 (transmembrane phosphoinositide 3-phosphatase and tensin homolog 2 [Source:NCBI gene;Acc:548705]) HSP 1 Score: 166.777 bits (421), Expect = 3.503e-45 Identity = 83/217 (38.25%), Postives = 125/217 (57.60%), Query Frame = 2
Query: 68 MNSTIRTIVSKKKRRYKKQGFNLDLSYVTSRIIAMGFPAEKFEALYRNDIDDVSKFFEVNHCGKYKIYNLCRERNFNASKFSGEIARFPFDDHNAPIFTDLVACVNDIAQFLDSCPDNVVAINCKAGKGRTGVIVCCTLIHCENNKDATTALQDYGKSRTLNG-----KGVTIPSQIRYIFYYDHFVKNKLKYASIP---LWLRKINFEMVPNIGNA 694
+ R +VS+ KRRY+K GF+LDL+Y+T RIIAM FP+ ++ YRN I++V++F + H YKIYNLC E+ ++ F + R DDHN P+ D++ + ++ P NV+AI+CK GKGRTG +VC L+ + + A +L +G+ RT +GV PSQ RY+ YY+ +KNK P L +R I + +G +
Sbjct: 120 LEKVTRRLVSENKRRYQKDGFDLDLTYITDRIIAMSFPSSGKQSFYRNPIEEVARFLDSKHQDHYKIYNLCSEKGYDPKYFHYRVERVFIDDHNVPVLADMLTFTASVRAWMAEDPQNVIAIHCKGGKGRTGTMVCTYLVDSDQFESAVESLDYFGERRTDTSVSTKFQGVETPSQSRYVAYYE-VLKNKFSRQLPPEKQLKIRSIRIYSIQGVGRS 335
BLAST of Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN vs. Ensembl Xenopus
Match: tpte2 (transmembrane phosphoinositide 3-phosphatase and tensin homolog 2 [Source:NCBI gene;Acc:548705]) HSP 1 Score: 167.162 bits (422), Expect = 6.046e-45 Identity = 83/217 (38.25%), Postives = 125/217 (57.60%), Query Frame = 2
Query: 68 MNSTIRTIVSKKKRRYKKQGFNLDLSYVTSRIIAMGFPAEKFEALYRNDIDDVSKFFEVNHCGKYKIYNLCRERNFNASKFSGEIARFPFDDHNAPIFTDLVACVNDIAQFLDSCPDNVVAINCKAGKGRTGVIVCCTLIHCENNKDATTALQDYGKSRTLNG-----KGVTIPSQIRYIFYYDHFVKNKLKYASIP---LWLRKINFEMVPNIGNA 694
+ R +VS+ KRRY+K GF+LDL+Y+T RIIAM FP+ ++ YRN I++V++F + H YKIYNLC E+ ++ F + R DDHN P+ D++ + ++ P NV+AI+CK GKGRTG +VC L+ + + A +L +G+ RT +GV PSQ RY+ YY+ +KNK P L +R I + +G +
Sbjct: 178 LEKVTRRLVSENKRRYQKDGFDLDLTYITDRIIAMSFPSSGKQSFYRNPIEEVARFLDSKHQDHYKIYNLCSEKGYDPKYFHYRVERVFIDDHNVPVLADMLTFTASVRAWMAEDPQNVIAIHCKGGKGRTGTMVCTYLVDSDQFESAVESLDYFGERRTDTSVSTKFQGVETPSQSRYVAYYE-VLKNKFSRQLPPEKQLKIRSIRIYSIQGVGRS 393
BLAST of Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN vs. Ensembl Xenopus
Match: tpte2 (transmembrane phosphoinositide 3-phosphatase and tensin homolog 2 [Source:NCBI gene;Acc:548705]) HSP 1 Score: 166.007 bits (419), Expect = 9.168e-45 Identity = 83/217 (38.25%), Postives = 125/217 (57.60%), Query Frame = 2
Query: 68 MNSTIRTIVSKKKRRYKKQGFNLDLSYVTSRIIAMGFPAEKFEALYRNDIDDVSKFFEVNHCGKYKIYNLCRERNFNASKFSGEIARFPFDDHNAPIFTDLVACVNDIAQFLDSCPDNVVAINCKAGKGRTGVIVCCTLIHCENNKDATTALQDYGKSRTLNG-----KGVTIPSQIRYIFYYDHFVKNKLKYASIP---LWLRKINFEMVPNIGNA 694
+ R +VS+ KRRY+K GF+LDL+Y+T RIIAM FP+ ++ YRN I++V++F + H YKIYNLC E+ ++ F + R DDHN P+ D++ + ++ P NV+AI+CK GKGRTG +VC L+ + + A +L +G+ RT +GV PSQ RY+ YY+ +KNK P L +R I + +G +
Sbjct: 141 LEKVTRRLVSENKRRYQKDGFDLDLTYITDRIIAMSFPSSGKQSFYRNPIEEVARFLDSKHQDHYKIYNLCSEKGYDPKYFHYRVERVFIDDHNVPVLADMLTFTASVRAWMAEDPQNVIAIHCKGGKGRTGTMVCTYLVDSDQFESAVESLDYFGERRTDTSVSTKFQGVETPSQSRYVAYYE-VLKNKFSRQLPPEKQLKIRSIRIYSIQGVGRS 356
BLAST of Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN vs. Ensembl Mouse
Match: Pten (phosphatase and tensin homolog [Source:MGI Symbol;Acc:MGI:109583]) HSP 1 Score: 245.743 bits (626), Expect = 1.827e-75 Identity = 141/361 (39.06%), Postives = 207/361 (57.34%), Query Frame = 2
Query: 68 MNSTIRTIVSKKKRRYKKQGFNLDLSYVTSRIIAMGFPAEKFEALYRNDIDDVSKFFEVNHCGKYKIYNLCRERNFNASKFSGEIARFPFDDHNAPIFTDLVACVNDIAQFLDSCPDNVVAINCKAGKGRTGVIVCCTLIHCENNKDATTALQDYGKSRTLNGKGVTIPSQIRYIFYYDHFVKNKLKYASIPLWLRKINFEMVPNIGNAEVEYAIYRVNSQNKIXXXXXXXXXXQDRQITFVESISYPLEDDLKFQFFYK-TLMGGTKILCQCWLNTFFIVNQPLIQCLDPVPRKSNSKNVFNRLPSKPPSDEAKCPIARPEKPHENIYTIRLTKKEIDEANKDSTFRIFPENFSITFMFS 1147
M + I+ IVS+ KRRY++ GF+LDL+Y+ IIAMGFPAE+ E +YRN+IDDV +F + H YKIYNLC ER+++ +KF+ +A++PF+DHN P + D+ Q+L ++V AI+CKAGKGRTGV++C L+H A AL YG+ RT + KGVTIPSQ RY++YY + +KN L Y + L K+ FE +P + KIYSS + T ++D+ + F P+ D+K +FF+K M + W+NTFFI P P +++ K L + ++ C I R + E + + LTK ++D+ANKD R F NF + F+
Sbjct: 1 MTAIIKEIVSRNKRRYQEDGFDLDLTYIYPNIIAMGFPAERLEGVYRNNIDDVVRFLDSKHKNHYKIYNLCAERHYDTAKFNCRVAQYPFEDHNPPQLELIKPFCEDLDQWLSEDDNHVAAIHCKAGKGRTGVMICAYLLHRGKFLKAQEALDFYGEVRTRDKKGVTIPSQRRYVYYYSYLLKNHLDYRPVALLFHKMMFETIPMFSGGTCNPQFVVCQLKVKIYSSNSGPTRREDKFMYFEFPQPLPVCGDIKVEFFHKQNKMLKKDKMFHFWVNTFFI----------PGPEETSEKVENGSLCDQ--EIDSICSIERADNDKEYL-VLTLTKNDLDKANKDKANRYFSPNFKVKLYFT 348
BLAST of Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN vs. Ensembl Mouse
Match: Tpte (transmembrane phosphatase with tensin homology [Source:MGI Symbol;Acc:MGI:2446460]) HSP 1 Score: 159.844 bits (403), Expect = 6.125e-42 Identity = 77/179 (43.02%), Postives = 109/179 (60.89%), Query Frame = 2
Query: 83 RTIVSKKKRRYKKQGFNLDLSYVTSRIIAMGFPAEKFEALYRNDIDDVSKFFEVNHCGKYKIYNLCRERNFNASKFSGEIARFPFDDHNAPIFTDLVACVNDIAQFLDSCPDNVVAINCKAGKGRTGVIVCCTLIHCENNKDATTALQDYGKSRTLNG-----KGVTIPSQIRYIFYYD 604
R +VS KRRYKK GF+LDL+YVT RIIAM FP+ E+ YRN I +V +F + H Y++YNLC ER ++ F + R DDHN P +++ ++ ++ P+NVVAI+CK GKGRTG +VC LI E +A +L +G+ RT +G+ PSQ RY+ Y++
Sbjct: 340 RKLVSGNKRRYKKDGFDLDLTYVTERIIAMSFPSSGRESFYRNPIKEVVRFLDTKHPNHYQVYNLCSERAYDPKHFHYRVRRIMIDDHNVPTLEEMLLFSKEVNNWMAQDPENVVAIHCKGGKGRTGTMVCACLIASEIVLNAKESLYFFGERRTDKSNSSKFQGIETPSQNRYVKYFE 518
BLAST of Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN vs. Ensembl Mouse
Match: Tpte (transmembrane phosphatase with tensin homology [Source:MGI Symbol;Acc:MGI:2446460]) HSP 1 Score: 159.844 bits (403), Expect = 1.354e-41 Identity = 77/179 (43.02%), Postives = 109/179 (60.89%), Query Frame = 2
Query: 83 RTIVSKKKRRYKKQGFNLDLSYVTSRIIAMGFPAEKFEALYRNDIDDVSKFFEVNHCGKYKIYNLCRERNFNASKFSGEIARFPFDDHNAPIFTDLVACVNDIAQFLDSCPDNVVAINCKAGKGRTGVIVCCTLIHCENNKDATTALQDYGKSRTLNG-----KGVTIPSQIRYIFYYD 604
R +VS KRRYKK GF+LDL+YVT RIIAM FP+ E+ YRN I +V +F + H Y++YNLC ER ++ F + R DDHN P +++ ++ ++ P+NVVAI+CK GKGRTG +VC LI E +A +L +G+ RT +G+ PSQ RY+ Y++
Sbjct: 340 RKLVSGNKRRYKKDGFDLDLTYVTERIIAMSFPSSGRESFYRNPIKEVVRFLDTKHPNHYQVYNLCSERAYDPKHFHYRVRRIMIDDHNVPTLEEMLLFSKEVNNWMAQDPENVVAIHCKGGKGRTGTMVCACLIASEIVLNAKESLYFFGERRTDKSNSSKFQGIETPSQNRYVKYFE 518
BLAST of Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN vs. Ensembl Mouse
Match: Tns1 (tensin 1 [Source:MGI Symbol;Acc:MGI:104552]) HSP 1 Score: 100.138 bits (248), Expect = 2.172e-21 Identity = 55/185 (29.73%), Postives = 96/185 (51.89%), Query Frame = 2
Query: 134 LDLSYVTSRIIAMGFPAEKFEALYRNDIDDVSKFFEVNHCGKYKIYNLCRERNFNASKFSGEIARFPFDDHNAPIFTDLVACVNDIAQFLDSCPDNVVAINCKAGKGRTGVIVCCTLIHCENNKDATTALQDYGKSRTLNGKGVTI--PSQIRYIFYYDHFVKNKLKYASIPLWLRKINFEMVPN 682
LDL YVT RIIA+ FP+ E +R+++ +V++ + H G Y ++NL +R + +K ++ F + D + P + + + +L++ P NVV ++ K +GR GV++ L + + A AL + R K V I PSQ RY+ Y+ + +K + PL+L + +PN
Sbjct: 15 LDLVYVTERIIAVSFPSTANEENFRSNLREVAQMLKSKHGGNYLLFNLSEQRP-DITKLHAKVLEFGWPDLHTPALEKICSVCKAMDTWLNADPHNVVVLHNKGNRGRIGVVIAAYLHYSNISASADQALDRFAMKRFYEDKIVPIGQPSQRRYVHYFSGLLSGSIKMNNKPLFLHHVIMHGIPN 198
BLAST of Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN vs. Ensembl Mouse
Match: Tns1 (tensin 1 [Source:MGI Symbol;Acc:MGI:104552]) HSP 1 Score: 100.138 bits (248), Expect = 2.186e-21 Identity = 55/185 (29.73%), Postives = 96/185 (51.89%), Query Frame = 2
Query: 134 LDLSYVTSRIIAMGFPAEKFEALYRNDIDDVSKFFEVNHCGKYKIYNLCRERNFNASKFSGEIARFPFDDHNAPIFTDLVACVNDIAQFLDSCPDNVVAINCKAGKGRTGVIVCCTLIHCENNKDATTALQDYGKSRTLNGKGVTI--PSQIRYIFYYDHFVKNKLKYASIPLWLRKINFEMVPN 682
LDL YVT RIIA+ FP+ E +R+++ +V++ + H G Y ++NL +R + +K ++ F + D + P + + + +L++ P NVV ++ K +GR GV++ L + + A AL + R K V I PSQ RY+ Y+ + +K + PL+L + +PN
Sbjct: 15 LDLVYVTERIIAVSFPSTANEENFRSNLREVAQMLKSKHGGNYLLFNLSEQRP-DITKLHAKVLEFGWPDLHTPALEKICSVCKAMDTWLNADPHNVVVLHNKGNRGRIGVVIAAYLHYSNISASADQALDRFAMKRFYEDKIVPIGQPSQRRYVHYFSGLLSGSIKMNNKPLFLHHVIMHGIPN 198
BLAST of Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN vs. UniProt/SwissProt
Match: sp|O08586|PTEN_MOUSE (Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN OS=Mus musculus OX=10090 GN=Pten PE=1 SV=1) HSP 1 Score: 245.743 bits (626), Expect = 1.278e-74 Identity = 141/361 (39.06%), Postives = 207/361 (57.34%), Query Frame = 2
Query: 68 MNSTIRTIVSKKKRRYKKQGFNLDLSYVTSRIIAMGFPAEKFEALYRNDIDDVSKFFEVNHCGKYKIYNLCRERNFNASKFSGEIARFPFDDHNAPIFTDLVACVNDIAQFLDSCPDNVVAINCKAGKGRTGVIVCCTLIHCENNKDATTALQDYGKSRTLNGKGVTIPSQIRYIFYYDHFVKNKLKYASIPLWLRKINFEMVPNIGNAEVEYAIYRVNSQNKIXXXXXXXXXXQDRQITFVESISYPLEDDLKFQFFYK-TLMGGTKILCQCWLNTFFIVNQPLIQCLDPVPRKSNSKNVFNRLPSKPPSDEAKCPIARPEKPHENIYTIRLTKKEIDEANKDSTFRIFPENFSITFMFS 1147
M + I+ IVS+ KRRY++ GF+LDL+Y+ IIAMGFPAE+ E +YRN+IDDV +F + H YKIYNLC ER+++ +KF+ +A++PF+DHN P + D+ Q+L ++V AI+CKAGKGRTGV++C L+H A AL YG+ RT + KGVTIPSQ RY++YY + +KN L Y + L K+ FE +P + KIYSS + T ++D+ + F P+ D+K +FF+K M + W+NTFFI P P +++ K L + ++ C I R + E + + LTK ++D+ANKD R F NF + F+
Sbjct: 1 MTAIIKEIVSRNKRRYQEDGFDLDLTYIYPNIIAMGFPAERLEGVYRNNIDDVVRFLDSKHKNHYKIYNLCAERHYDTAKFNCRVAQYPFEDHNPPQLELIKPFCEDLDQWLSEDDNHVAAIHCKAGKGRTGVMICAYLLHRGKFLKAQEALDFYGEVRTRDKKGVTIPSQRRYVYYYSYLLKNHLDYRPVALLFHKMMFETIPMFSGGTCNPQFVVCQLKVKIYSSNSGPTRREDKFMYFEFPQPLPVCGDIKVEFFHKQNKMLKKDKMFHFWVNTFFI----------PGPEETSEKVENGSLCDQ--EIDSICSIERADNDKEYL-VLTLTKNDLDKANKDKANRYFSPNFKVKLYFT 348
BLAST of Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN vs. UniProt/SwissProt
Match: sp|P60484|PTEN_HUMAN (Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN OS=Homo sapiens OX=9606 GN=PTEN PE=1 SV=1) HSP 1 Score: 245.743 bits (626), Expect = 1.347e-74 Identity = 141/361 (39.06%), Postives = 207/361 (57.34%), Query Frame = 2
Query: 68 MNSTIRTIVSKKKRRYKKQGFNLDLSYVTSRIIAMGFPAEKFEALYRNDIDDVSKFFEVNHCGKYKIYNLCRERNFNASKFSGEIARFPFDDHNAPIFTDLVACVNDIAQFLDSCPDNVVAINCKAGKGRTGVIVCCTLIHCENNKDATTALQDYGKSRTLNGKGVTIPSQIRYIFYYDHFVKNKLKYASIPLWLRKINFEMVPNIGNAEVEYAIYRVNSQNKIXXXXXXXXXXQDRQITFVESISYPLEDDLKFQFFYK-TLMGGTKILCQCWLNTFFIVNQPLIQCLDPVPRKSNSKNVFNRLPSKPPSDEAKCPIARPEKPHENIYTIRLTKKEIDEANKDSTFRIFPENFSITFMFS 1147
M + I+ IVS+ KRRY++ GF+LDL+Y+ IIAMGFPAE+ E +YRN+IDDV +F + H YKIYNLC ER+++ +KF+ +A++PF+DHN P + D+ Q+L ++V AI+CKAGKGRTGV++C L+H A AL YG+ RT + KGVTIPSQ RY++YY + +KN L Y + L K+ FE +P + KIYSS + T ++D+ + F P+ D+K +FF+K M + W+NTFFI P P +++ K L + ++ C I R + E + + LTK ++D+ANKD R F NF + F+
Sbjct: 1 MTAIIKEIVSRNKRRYQEDGFDLDLTYIYPNIIAMGFPAERLEGVYRNNIDDVVRFLDSKHKNHYKIYNLCAERHYDTAKFNCRVAQYPFEDHNPPQLELIKPFCEDLDQWLSEDDNHVAAIHCKAGKGRTGVMICAYLLHRGKFLKAQEALDFYGEVRTRDKKGVTIPSQRRYVYYYSYLLKNHLDYRPVALLFHKMMFETIPMFSGGTCNPQFVVCQLKVKIYSSNSGPTRREDKFMYFEFPQPLPVCGDIKVEFFHKQNKMLKKDKMFHFWVNTFFI----------PGPEETSEKVENGSLCDQ--EIDSICSIERADNDKEYL-VLTLTKNDLDKANKDKANRYFSPNFKVKLYFT 348
BLAST of Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN vs. UniProt/SwissProt
Match: sp|P60483|PTEN_CANLF (Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN OS=Canis lupus familiaris OX=9615 GN=PTEN PE=2 SV=1) HSP 1 Score: 245.743 bits (626), Expect = 1.347e-74 Identity = 141/361 (39.06%), Postives = 207/361 (57.34%), Query Frame = 2
Query: 68 MNSTIRTIVSKKKRRYKKQGFNLDLSYVTSRIIAMGFPAEKFEALYRNDIDDVSKFFEVNHCGKYKIYNLCRERNFNASKFSGEIARFPFDDHNAPIFTDLVACVNDIAQFLDSCPDNVVAINCKAGKGRTGVIVCCTLIHCENNKDATTALQDYGKSRTLNGKGVTIPSQIRYIFYYDHFVKNKLKYASIPLWLRKINFEMVPNIGNAEVEYAIYRVNSQNKIXXXXXXXXXXQDRQITFVESISYPLEDDLKFQFFYK-TLMGGTKILCQCWLNTFFIVNQPLIQCLDPVPRKSNSKNVFNRLPSKPPSDEAKCPIARPEKPHENIYTIRLTKKEIDEANKDSTFRIFPENFSITFMFS 1147
M + I+ IVS+ KRRY++ GF+LDL+Y+ IIAMGFPAE+ E +YRN+IDDV +F + H YKIYNLC ER+++ +KF+ +A++PF+DHN P + D+ Q+L ++V AI+CKAGKGRTGV++C L+H A AL YG+ RT + KGVTIPSQ RY++YY + +KN L Y + L K+ FE +P + KIYSS + T ++D+ + F P+ D+K +FF+K M + W+NTFFI P P +++ K L + ++ C I R + E + + LTK ++D+ANKD R F NF + F+
Sbjct: 1 MTAIIKEIVSRNKRRYQEDGFDLDLTYIYPNIIAMGFPAERLEGVYRNNIDDVVRFLDSKHKNHYKIYNLCAERHYDTAKFNCRVAQYPFEDHNPPQLELIKPFCEDLDQWLSEDDNHVAAIHCKAGKGRTGVMICAYLLHRGKFLKAQEALDFYGEVRTRDKKGVTIPSQRRYVYYYSYLLKNHLDYRPVALLFHKMMFETIPMFSGGTCNPQFVVCQLKVKIYSSNSGPTRREDKFMYFEFPQPLPVCGDIKVEFFHKQNKMLKKDKMFHFWVNTFFI----------PGPEETSEKVENGSLCDQ--EIDSICSIERADNDKEYL-VLTLTKNDLDKANKDKANRYFSPNFKVKLYFT 348
BLAST of Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN vs. UniProt/SwissProt
Match: sp|Q9PUT6|PTEN_XENLA (Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN OS=Xenopus laevis OX=8355 GN=pten PE=2 SV=1) HSP 1 Score: 243.047 bits (619), Expect = 1.060e-73 Identity = 141/365 (38.63%), Postives = 210/365 (57.53%), Query Frame = 2
Query: 68 MNSTIRTIVSKKKRRYKKQGFNLDLSYVTSRIIAMGFPAEKFEALYRNDIDDVSKFFEVNHCGKYKIYNLCRERNFNASKFSGEIARFPFDDHNAPIFTDLVACVNDIAQFLDSCPDNVVAINCKAGKGRTGVIVCCTLIHCENNKDATTALQDYGKSRTLNGKGVTIPSQIRYIFYYDHFVKNKLKYASIPLWLRKINFEMVPNIGNAEV--EYAIYRVNSQNKIXXXXXXXXXXQDRQITFVE-SISYPLEDDLKFQFFYKT--LMGGTKILCQCWLNTFFIVNQPLIQCLDPVPRKSNSKNVFNRLPSKPPSDEAKCPIARPEKPHENIYTIRLTKKEIDEANKDSTFRIFPENFSITFMFS 1147
M + I+ VS+ KRRY++ GF+LDL+Y+ IIAMGFPAE+ E +YRN+IDDV +F + H YKIYNLC ER+++ +KFS +A++PF+DHN P + D+ Q L S +NV AI+CKAGKGRTGV++C L+H A AL YG+ RT + KGVTIPSQ RY++YY + +KN L+Y +PL KI FE +P + ++ +Y++ K+ + K+ ++ + + P+ D+K +FF+K +M K+ W+NTFFI P P + + K L + D R + E + T+ LTK ++D+ANKD R+F NF + F+
Sbjct: 1 MTAIIKEFVSRNKRRYQEDGFDLDLTYIYPNIIAMGFPAERLEGVYRNNIDDVVRFLDSKHKNHYKIYNLCAERHYDTNKFSCRVAQYPFEDHNPPQLELIKPFCEDLDQLL-SENENVAAIHCKAGKGRTGVMICAYLLHRGKFPRAQEALDFYGEVRTRDKKGVTIPSQRRYVYYYSYLLKNSLEYRPVPLLFHKIEFETIPMFSGSTCNPQFVVYQL----KVKIFTSTAGPKRAEKLMYFDFPQPLPVCGDIKVEFFHKQNKVMKKEKMF-HFWVNTFFI----------PGPEEYSEKVENGTLVGEQELD-GIYSTERSDNDKEYL-TLALTKNDLDKANKDKANRLFSPNFKVKLFFT 347
BLAST of Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN vs. UniProt/SwissProt
Match: sp|Q8T9S7|PTEN_DICDI (Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN OS=Dictyostelium discoideum OX=44689 GN=pteN PE=2 SV=1) HSP 1 Score: 204.912 bits (520), Expect = 8.400e-58 Identity = 96/216 (44.44%), Postives = 143/216 (66.20%), Query Frame = 2
Query: 68 MNSTIRTIVSKKKRRYKKQGFNLDLSYVTSRIIAMGFPAEKFEALYRNDIDDVSKFFEVNHCGKYKIYNLCRERNFNASKFSGEIARFPFDDHNAPIFTDLVACVNDIAQFLDSCPDNVVAINCKAGKGRTGVIVCCTLIHCENNKDATTALQDYGKSRTLNGKGVTIPSQIRYIFYYDHFVKNKLKYASIPLWLRKINFEMVP-NIGNAEVEYAI 712
M++ +R VSK+KRRY+K G++LDL+Y+T I+AMGFP+EK E ++RN + DV +F + H +K+YNLC ER ++ SKF G + +PFDDHNAP F + A D+ ++ N+ I+CKAGKGRTG+++CC L++C K+ +L+ Y RT N KGVTIPSQIRY+ Y+ ++ +KY + L+KI +P I +EV++ I
Sbjct: 1 MSNLLRVAVSKQKRRYQKNGYDLDLAYITDNIVAMGFPSEKVEGVFRNPMKDVQRFLDQYHKDHFKVYNLCSERVYDHSKFYGRVGYYPFDDHNAPQFEMIDAFCRDVDAWMKEDSKNIAVIHCKAGKGRTGLMICCWLMYCGMWKNTEDSLRFYAALRTYNQKGVTIPSQIRYVGYFGRSIRESIKYVPRNVTLKKIVLRPLPKEINLSEVQFNI 216
BLAST of Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN vs. TrEMBL
Match: A0A0U4VVW9 (Hr-PTEN protein OS=Halocynthia roretzi OX=7729 GN=Hr-PTEN PE=2 SV=1) HSP 1 Score: 267.7 bits (683), Expect = 7.501e-80 Identity = 147/361 (40.72%), Postives = 215/361 (59.56%), Query Frame = 2
Query: 68 MNSTIRTIVSKKKRRYKKQGFNLDLSYVTSRIIAMGFPAEKFEALYRNDIDDVSKFFEVNHCGKYKIYNLCRERNFNASKFSGEIARFPFDDHNAPIFTDLVACVNDIAQFLDSCPDNVVAINCKAGKGRTGVIVCCTLIHCENNKDATTALQDYGKSRTLNGKGVTIPSQIRYIFYYDHFVKNKLKYASIPLWLRKINFEMVPNIGNAEVEYAIYRVNSQNKIXXXXXXXXXXQDRQITFVESISYPLEDDLKFQFFYKTLMGGTKILCQCWLNTFFIVNQPLIQCLDPVPRKSNSKNVFNRLPSKPPSDEAKCPIARPEKPHE-NIYTIRLTKKEIDEANKDSTFRIFPENFSITFMFS 1147
M++TI+++VSKKKRRY++ GF+LDL+Y+ I+AMGFPAEK E LYRN+IDDV KF E H YK+YNLC ER ++ KF +A FPFDDHN P F + +D+ +L +N+ A++CKAGKGRTGV++CC L+H AL+ YG++RT+N KGVTIPSQ RY+ YY +K+ L Y L L I F+ VP I N + + ++ + K+++S + + DR + F PL D+K +FF + +MG K+ W NTFF+ + P R + + N +P+ +C PHE ++ T+ + K E+D+ANKD ++F NF + +FS
Sbjct: 1 MSNTIKSMVSKKKRRYREGGFDLDLTYICPNILAMGFPAEKVEGLYRNNIDDVVKFLESKHPDHYKVYNLCSERTYDPDKFCKRVAAFPFDDHNPPKFELIKPFCDDMDLWLRKDKNNIAAVHCKAGKGRTGVMICCYLLHRRKFSTTADALRFYGQARTMNDKGVTIPSQRRYVEYYAEMLKHNLTYKPDTLLLHSIPFDTVPLIHNLNPFFVVNQL--KVKLFTSNPDRVVRNDRLLIFDLPQPLPLCGDMKIEFFSRKVMGKEKLF-HFWFNTFFVQ-----RMQKPEKRHTGASYPNNIVPNGSARSYYRC----KHMPHEKDMLTLTIPKMELDKANKDRANKLFSPNFKVILIFS 349
BLAST of Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN vs. TrEMBL
Match: A0A3P8XQB9 (Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN OS=Esox lucius OX=8010 PE=3 SV=1) HSP 1 Score: 259.996 bits (663), Expect = 1.404e-77 Identity = 145/365 (39.73%), Postives = 221/365 (60.55%), Query Frame = 2
Query: 68 MNSTIRTIVSKKKRRYKKQGFNLDLSYVTSRIIAMGFPAEKFEALYRNDIDDVSKFFEVNHCGKYKIYNLCRERNFNASKFSGEIARFPFDDHNAPIFTDLVACVNDIAQFLDSCPDNVVAINCKAGKGRTGVIVCCTLIHCENNKDATTALQDYGKSRTLNGKGVTIPSQIRYIFYYDHFVKNKLKYASIPLWLRKINFEMVP--NIGNAEVEYAIYRVNSQNKIXXXXXXXXXXQDRQITFVESISYPLEDDLKFQFFYKT--LMGGTKILCQCWLNTFFIVNQPLIQCLDPVPRKSNSKNVFNRLPSKPPSDEAKCPIARPEKPHENIYTI-RLTKKEIDEANKDSTFRIFPENFSITFMFS 1147
M + I+ +VS+ KRRY++ GF+LDL+Y+ IIAMGFPAE+ E +YRN+IDDV +F + H YKIYNLC ER+++A+KF+ +A+FPF+DHN P + D+ Q+L ++V AI+CKAGKGRTGV++C L+H ++A AL YG+ RT + KGVTIPSQ RY++YY H +KNKL Y + L K+ FE +P + G ++ +Y++ KI++S T ++++ + F P+ D+K +FF+K +M K+ W+NTFFI P + L+ V S N + + ++ P + P + + + Y I LTK ++D+ANKD R F NF + F+
Sbjct: 1 MAAIIKEMVSRNKRRYQEDGFDLDLTYIYPNIIAMGFPAERLEGVYRNNIDDVVRFLDSKHKDHYKIYNLCAERHYDAAKFNCRVAQFPFEDHNPPQLELIKPFCEDLDQWLSKDDNHVAAIHCKAGKGRTGVMICAYLLHRGKFQEAQEALDFYGEVRTRDKKGVTIPSQRRYVYYYSHLLKNKLDYKPVALLFHKMVFETLPMFSGGTCNPQFVVYQLKV--KIHTSNPAHTRREEKHMLFEFPQPLPVCGDIKVEFFHKQNKMMKKDKMF-HFWVNTFFIPGPPE-ESLEKVENGSVVVNDVDGVQNQ-PQGAPQLPQSAEHRDSDRDYLILALTKNDLDKANKDKANRYFSPNFKVMLYFT 360
BLAST of Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN vs. TrEMBL
Match: A0A4W5NIQ6 (Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN OS=Hucho hucho OX=62062 PE=3 SV=1) HSP 1 Score: 257.684 bits (657), Expect = 4.957e-76 Identity = 147/375 (39.20%), Postives = 224/375 (59.73%), Query Frame = 2
Query: 68 MNSTIRTIVSKKKRRYKKQGFNLDLSYVTSRIIAMGFPAEKFEALYRNDIDDVSKFFEVNHCGKYKIYNLCRERNFNASKFSGEIARFPFDDHNAPIFTDLVACVNDIAQFLDSCPDNVVAINCKAGKGRTGVIVCCTLIHCENNKDATTALQDYGKSRTLNGKGVTIPSQIRYIFYYDHFVKNKLKYASIPLWLRKINFEMVP--NIGNAEVEYAIYRVNSQNKIXXXXXXXXXXQDRQITFVESISYPLEDDLKFQFFYKT--LMGGTKILCQCWLNTFFIVNQPLIQCLDPVPRKS------NSKNVFNRLPSKPPSDEAKCPIARPE----KPHENIYTI-RLTKKEIDEANKDSTFRIFPENFSITFMFS 1147
M + I+ +VS+ KRRY++ GF+LDL+Y+ IIAMGFPAE+ E +YRN+IDDV +F + H YKIYNLC ER+++A+KF+ +A++PF+DHN P + D+ Q+L ++V AI+CKAGKGRTGV++C L+H ++ AL YG+ RT + KGVTIPSQ RY++YY H +KNKL Y + L K+ FE +P + G ++ +Y++ + KI++S T ++++ + F P+ D+K +FF+K +M K+ W+NTFFI P + ++ V S + + V N+ P PP A+ P + K + Y I LTK ++D+ANKD R F NF + F+
Sbjct: 1 MAAIIKEMVSRNKRRYQEDGFDLDLTYIYPNIIAMGFPAERLEGVYRNNIDDVVRFLDSKHKSHYKIYNLCVERHYDAAKFNCRVAQYPFEDHNPPQLELIKPFCEDLDQWLSEDDNHVAAIHCKAGKGRTGVMICAYLLHRSKFQEPQEALDFYGEVRTRDKKGVTIPSQRRYVYYYSHLLKNKLDYKPVALLFHKMVFETLPMFSGGTCNPQFVVYQL--KVKIHTSNPAHTRREEKHMLFEFPQPLPVCGDIKVEFFHKQNKMMKKDKMF-HFWVNTFFIPG-PSEESMEKVENGSVVVVVNDMEGVQNQPPGAPPP-HARSPQSAKRRDSGKDSDGDYLILALTKNDLDKANKDKANRYFSPNFKVKLYFT 370
BLAST of Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN vs. TrEMBL
Match: A0A3Q3K1X2 (Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN OS=Monopterus albus OX=43700 PE=3 SV=1) HSP 1 Score: 255.758 bits (652), Expect = 7.056e-76 Identity = 142/370 (38.38%), Postives = 218/370 (58.92%), Query Frame = 2
Query: 68 MNSTIRTIVSKKKRRYKKQGFNLDLSYVTSRIIAMGFPAEKFEALYRNDIDDVSKFFEVNHCGKYKIYNLCRERNFNASKFSGEIARFPFDDHNAPIFTDLVACVNDIAQFLDSCPDNVVAINCKAGKGRTGVIVCCTLIHCENNKDATTALQDYGKSRTLNGKGVTIPSQIRYIFYYDHFVKNKLKYASIPLWLRKINFEMVP--NIGNAEVEYAIYRVNSQNKIXXXXXXXXXXQDRQITFVESISYPLEDDLKFQFFYKT--LMGGTKILCQCWLNTFFIVNQPLIQCLDPVPRKSNSK---NVFNRLPSK---PPSDEAKCPIARPEKPHENIYTIRLTKKEIDEANKDSTFRIFPENFSITFMFS 1147
M + I+ +VS+ KRRY++ GF+LDL+Y+ IIAMGFPAE+ E +YRN+IDDV +F + H YKIYNLC ER+++A+KF+ +A++PF+DHN P + D+ ++L ++V AI+CKAGKGRTGV++C L+H +A AL YG+ RT + KGVTIPSQ RY++YY + +KN+L+Y + L K+ FE +P + G ++ +Y++ KI++S T ++D+ + F P+ D+K +FF+K +M K+ W+NTFFI P P +S K N S+ P D+ + A + + + LTK ++D+ANKD R F NF + F+
Sbjct: 1 MAAIIKEMVSRNKRRYQEDGFDLDLTYIYPNIIAMGFPAERLEGVYRNNIDDVVRFLDSKHKNHYKIYNLCAERHYDAAKFNCRVAQYPFEDHNPPQLELIKPFCEDLDKWLSEDDNHVAAIHCKAGKGRTGVMICAYLLHRRKFHEAQEALDFYGEVRTRDKKGVTIPSQRRYVYYYSYLLKNQLEYKPVALLFHKMVFETLPMFSGGTCNPQFVVYQLKV--KIHTSNPTHTRREDKHMLFEFPQPLPVCGDIKVEFFHKQNKMMKKDKMF-HFWVNTFFI----------PGPEESGDKMENGAVNNAESQQGGPGPDQGQPHSAEVRQSDRDYLILTLTKNDLDKANKDKANRYFSPNFKVKLYFT 357
BLAST of Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN vs. TrEMBL
Match: R7UIY8 (Uncharacterized protein OS=Capitella teleta OX=283909 GN=CAPTEDRAFT_90711 PE=4 SV=1) HSP 1 Score: 254.603 bits (649), Expect = 7.795e-76 Identity = 138/364 (37.91%), Postives = 205/364 (56.32%), Query Frame = 2
Query: 68 MNSTIRTIVSKKKRRYKKQGFNLDLSYVTSRIIAMGFPAEKFEALYRNDIDDVSKFFEVNHCGKYKIYNLCRERNFNASKFSGEIARFPFDDHNAPIFTDLVACVNDIAQFLDSCPDNVVAINCKAGKGRTGVIVCCTLIHCENNKDATTALQDYGKSRTLNGKGVTIPSQIRYIFYYDHFVKNKLKYASIPLWLRKINFEMVPNI--GNAEVEYAIYRVNSQNKIXXXXXXXXXXQDRQITFVESISYPLEDDLKFQFFYK-TLMGGTKILCQCWLNTFFIVNQPLIQ-----CLDPVPRKSNSKNVFNRLPSKPPSDEAKCPIARPEKPHENIYTIRLTKKEIDEANKDSTFRIFPENFSIT 1135
M + I+ +VSK KRRY++ GF+LDLSY+ IIAMGFPAEK E +YRN+IDDV +F E H +YK+YNLC ER ++ SKF +A FPFDDH+ P + D+ +L NV I+CKAGKGRTGV++C L+HC KDA AL+ YG +RT++ KGVTIPSQ RY+ YY ++ L Y + L LR I FE +PN G+ + IY + ++ S+ K + +T + + P+ D++ +F+ K + M + + W NTFFI + Q C + + N ++ ++ P +T+ L+K+E+D+ANKD +I+ F ++
Sbjct: 1 MANKIKGLVSKNKRRYQEDGFDLDLSYIYPNIIAMGFPAEKLEGVYRNNIDDVVRFLEARHRDQYKVYNLCSERMYDTSKFHKRVAHFPFDDHHPPRLELIRPFCEDMDDWLSRNSQNVAVIHCKAGKGRTGVMICAYLLHCGRFKDAEEALRFYGDARTMDQKGVTIPSQRRYVNYYGQLIRRHLTYRPVTLQLRAIQFETIPNFNGGSCAPFFVIYHIKVKS-FTSTVFEGAKKGESNLTMLLPQAQPVGGDIRIEFYNKPSKMMKKEKMFHFWFNTFFICYEERTQAALNGCDSDAASQPRNNNARHQNHTRDEGSVPPPPPPPLPMDESRTFTLTLSKRELDKANKDKQHKIYSAGFKVS 363
BLAST of Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN vs. Ensembl Cavefish
Match: ENSAMXT00000043891.1 (phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN-like [Source:NCBI gene;Acc:103046962]) HSP 1 Score: 243.817 bits (621), Expect = 2.949e-74 Identity = 144/404 (35.64%), Postives = 222/404 (54.95%), Query Frame = 2
Query: 68 MNSTIRTIVSKKKRRYKKQGFNLDLSYVTSRIIAMGFPAEKFEALYRNDIDDVSKFFEVNHCGKYKIYNLCRERNFNASKFSGEIARFPFDDHNAPIFTDLVACVNDIAQFLDSCPDNVVAINCKAGKGRTGVIVCCTLIHCENNKDATTALQDYGKSRTLNGKGVTIPSQIRYIFYYDHFVKNKLKYASIPLWLRKINFEMVP--NIGNAEVEYAIYRVNSQNKIXXXXXXXXXXQDRQITFVESISYPLEDDLKFQFFYKT--LMGGTKILCQCWLNTFFIVNQPLIQCLDPVPRKSNSKNVFNRL----------PSK------------------------------PPSDEAKCPIARPEKPHENIYTIRLTKKEIDEANKDSTFRIFPENFSITFMFS 1147
M + I+ IVS+ KRRY++ GF+LDL+Y+ IIAMGFPAE+ E +YRN+IDDV +F + H YKIYNLC ER+++A+KF+ +A++PF+DHN P + D+ Q+L ++V AI+CKAGKGRTGV++C L+H + +A AL YG+ RT + KGVTIPSQ RY++YY H +KN+L+Y + L K+ FE +P + G ++ +Y++ KI++S T ++D+ + F P+ D+K +FF+K +M K+ W+NTFFI + P K + +V N + P++ + A P P+ + + + LTK ++D+ANKD R F NF + F+
Sbjct: 1 MAAIIKEIVSRNKRRYQEDGFDLDLTYIYPNIIAMGFPAERLEGVYRNNIDDVVRFLDSKHRNHYKIYNLCAERHYDAAKFNCRVAQYPFEDHNPPQLELIKPFCEDLDQWLSEDENHVAAIHCKAGKGRTGVMICAYLLHRQKFMEAQEALDFYGEVRTRDKKGVTIPSQRRYVYYYSHLLKNQLEYKPVALLFHKMVFETLPMFSGGTCNPQFVVYQLKV--KIHTSNPSHTRREDKHMFFEFPQPLPVCGDIKVEFFHKQNKMMKKDKMF-HFWVNTFFIPGP------EESPEKWENGSVVNDIDSNSSQSQSSPTERERGMGAGGGGGGGSGSSIGSGGGGGGSGGGERERAGEPAGAPDADRDYL-ILTLTKNDLDKANKDKANRYFSPNFKVKLYFT 394
BLAST of Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN vs. Ensembl Cavefish
Match: ENSAMXT00000007968.2 (phosphatase and tensin homolog [Source:NCBI gene;Acc:103025186]) HSP 1 Score: 239.965 bits (611), Expect = 2.108e-73 Identity = 140/364 (38.46%), Postives = 212/364 (58.24%), Query Frame = 2
Query: 68 MNSTIRTIVSKKKRRYKKQGFNLDLSYVTSRIIAMGFPAEKFEALYRNDIDDVSKFFEVNHCGKYKIYNLCRERNFNASKFSGEIARFPFDDHNAPIFTDLVACVNDIAQFLDSCPDNVVAINCKAGKGRTGVIVCCTLIHCENNKDATTALQDYGKSRTLNGKGVTIPSQIRYIFYYDHFVKNKLKYASIPLWLRKINFEMVPNI--GNAEVEYAIYRVNSQNKIXXXXXXXXXXQDRQITFVE-SISYPLEDDLKFQFF-YKTLMGGTKILCQCWLNTFFIVNQPLIQCLDPVPRKSNSKNVFNRLPSKPPSDEAKCPIARPEKPHENIYTIRLTKKEIDEANKDSTFRIFPENFSITFMFS 1147
M + I+ +VS+ KRRY++ GF+LDL+Y+ +IAMGFPAE+ E +YRN+IDDV +F + H YKIYNLC ER+++ +KF+ +A++PF+DHN P + D+ ++L ++V AI+CKAGKGRTGV++C L+H K A AL YG+ RT + KGVTIPSQ RY++YY + +KNKL Y + L K+ FE VP GN + +Y++ KI++S T ++D + E P+ D+K +FF + M + W+NTFFI P + L+ V K + DE + + + E + + + LTK ++D+ANKD R+F NF + F+
Sbjct: 1 MATIIQKMVSRNKRRYQEDGFDLDLTYIYPNLIAMGFPAERLEGVYRNNIDDVVRFLDSKHKNHYKIYNLCAERHYDTAKFNCRVAQYPFEDHNPPQLELIRPFCEDLDKWLGEHDNHVAAIHCKAGKGRTGVMICAYLLHQGKFKKAQEALDFYGEVRTRDKKGVTIPSQRRYVYYYSYLLKNKLDYKPVALLFHKMMFETVPMFSGGNCNPHFVVYQLKV--KIHTSNPGNTRREDNKCMHFEFPQPLPVCGDIKVEFFNRQNKMLKKDKMFHFWVNTFFI---PGPEKLEKVENGDLPKEL----------DEIQS-LEKGENDKDYL-ILTLTKHDLDKANKDKANRLFSPNFKVKLYFT 347
BLAST of Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN vs. Ensembl Cavefish
Match: ENSAMXT00000055423.1 (phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN-like [Source:NCBI gene;Acc:103046962]) HSP 1 Score: 233.802 bits (595), Expect = 3.063e-70 Identity = 143/427 (33.49%), Postives = 221/427 (51.76%), Query Frame = 2
Query: 68 MNSTIRTIVSKKKRRYKKQGFNLDLSYVTSRIIAMGFPAEKFEALYRNDIDDVSKFFEVNHCGKYKIYNLCRERNFNASKFSGEIARFPFDDHNAPIFTDLVACVNDIAQFLDSCPDNVVAINCKAGKGRTGVIVCCTLIHCENNKDATTALQDYGKSRTLNGKGVTIPSQIRYIFYYDHFVKNKLKYASIPLWLRKINFEMVPNIGNA-------------------------EVEYAIYRVNSQNKIXXXXXXXXXXQDRQITFVESISYPLEDDLKFQFFYKT--LMGGTKILCQCWLNTFFIVNQPLIQCLDPVPRKSNSKNVFNRL----------PSK------------------------------PPSDEAKCPIARPEKPHENIYTIRLTKKEIDEANKDSTFRIFPENFSITFMFS 1147
M + I+ IVS+ KRRY++ GF+LDL+Y+ IIAMGFPAE+ E +YRN+IDDV +F + H YKIYNLC ER+++A+KF+ +A++PF+DHN P + D+ Q+L ++V AI+CKAGKGRTGV++C L+H + +A AL YG+ RT + KGVTIPSQ RY++YY H +KN+L+Y + L K+ FE +P + ++ +Y++ KI++S T ++D+ + F P+ D+K +FF+K +M K+ W+NTFFI + P K + +V N + P++ + A P P+ + + + LTK ++D+ANKD R F NF + F+
Sbjct: 1 MAAIIKEIVSRNKRRYQEDGFDLDLTYIYPNIIAMGFPAERLEGVYRNNIDDVVRFLDSKHRNHYKIYNLCAERHYDAAKFNCRVAQYPFEDHNPPQLELIKPFCEDLDQWLSEDENHVAAIHCKAGKGRTGVMICAYLLHRQKFMEAQEALDFYGEVRTRDKKGVTIPSQRRYVYYYSHLLKNQLEYKPVALLFHKMVFETLPMFSGGTCRDSTVKNRSEANPQGFKKGNWHWDPQFVVYQLKV--KIHTSNPSHTRREDKHMFFEFPQPLPVCGDIKVEFFHKQNKMMKKDKMF-HFWVNTFFIPGP------EESPEKWENGSVVNDIDSNSSQSQSSPTERERGMGAGGGGGGGSGSSIGSGGGGGGSGGGERERAGEPAGAPDADRDYL-ILTLTKNDLDKANKDKANRYFSPNFKVKLYFT 417
BLAST of Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN vs. Ensembl Cavefish
Match: ENSAMXT00000038725.1 (phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN-like [Source:NCBI gene;Acc:103046962]) HSP 1 Score: 173.711 bits (439), Expect = 9.780e-49 Identity = 119/364 (32.69%), Postives = 186/364 (51.10%), Query Frame = 2
Query: 68 MNSTIRTIVSKKKRRYKKQGFNLDLSYVTSRIIAMGFPAEKFEALYRNDIDDVSKFFEVNHCGKYKIYNLCRERNFNASKFSGEIARFPFDDHNAPIFTDLVACVNDIAQFLDSCPDNVVAINCKAGKGRTGVIVCCTLIHCENNKDATTALQDYGKSRTLNGKGVTIPSQIRYIFYYDHFVKNKLKYASIPLWLRKINFEMVP--NIGNAEVEYAIYRVNSQNKIXXXXXXXXXXQDRQITFVESISYPLEDDLKFQFFYKT--LMGGTKILCQCWLNTFFIVNQPLIQCLDPVPRKSNSKNVFNRLPSKPPSDEAKCPIARPEKPHENIYTIRLTKKEIDEANKDSTFRIFPENFSITFMFS 1147
M + I+ IVS+ KRRY++ GF+LDL+Y+ IIAM + H ++ + N + E +PF+DHN P + D+ Q+L ++V AI+CKAGKGRTGV++C L+H + +A AL YG+ RT + KGVTIPSQ RY++YY H +KN+L+Y + L K+ FE +P + G ++ +Y++ KI++S T ++D+ + F P+ D+K +FF+K +M K+ W+NTFFI + P K + +V N + S S + P A + + LTK ++D+ANKD R F NF + F+
Sbjct: 1 MAAIIKEIVSRNKRRYQEDGFDLDLTYIYPNIIAM---------------------VHLQH-----VHTPAQ----NTRVYQEE---YPFEDHNPPQLELIKPFCEDLDQWLSEDENHVAAIHCKAGKGRTGVMICAYLLHRQKFMEAQEALDFYGEVRTRDKKGVTIPSQRRYVYYYSHLLKNQLEYKPVALLFHKMVFETLPMFSGGTCNPQFVVYQLKV--KIHTSNPSHTRREDKHMFFEFPQPLPVCGDIKVEFFHKQNKMMKKDKMF-HFWVNTFFIPGP------EESPEKWENGSVVNDIDSN--SSQTGAPDAD-----RDYLILTLTKNDLDKANKDKANRYFSPNFKVKLYFT 315
BLAST of Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN vs. Ensembl Cavefish
Match: ENSAMXT00000047718.1 (pep primary_assembly:Astyanax_mexicanus-2.0:APWO02001063.1:308295:333196:1 gene:ENSAMXG00000032162.1 transcript:ENSAMXT00000047718.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 103.219 bits (256), Expect = 9.394e-24 Identity = 57/200 (28.50%), Postives = 104/200 (52.00%), Query Frame = 2
Query: 107 RRYKKQGFNLDLSYVTSRIIAMGFPAEKFEALYRNDIDDVSKFFEVNHCGKYKIYNLCRERNFNASKFSGEIARFPFDDHNAPIFTDLVACVNDIAQFLDSCPDNVVAINCKAGKGRTGVIVCCTLIHCENNKDATTALQDYGKSRTLNGK--GVTIPSQIRYIFYYDHFVKNKLKYASIPLWLRKINFEMVPNIGNAEV 700
R ++G+ LDL+YVT RIIA+ FP E Y +++ DV++ + H Y + NL +R+ + ++ + + + D +AP + + +L++ P +VV I+C+ GKGR GV++C + + + A AL + + + K + PSQ RY++ + + +K + PL+L I +PN N+ V
Sbjct: 5 RTCMEEGYELDLTYVTERIIAVSFPQSCSEETYLHNLKDVTRMLKSKHADNYLVINLSEKRH-DLTRMNPKTLDTGWPDLHAPPLDKICTICKAMENWLNADPLHVVVIHCRGGKGRIGVVICSFVHFTDISASADQALDRFAMRKFYDDKVSALMTPSQKRYVWILNSLLSGSMKMNASPLFLHCIILHGIPNFDNSGV 203
BLAST of Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN vs. Ensembl Sea Lamprey
Match: TNS1 (tensin 1 [Source:HGNC Symbol;Acc:HGNC:11973]) HSP 1 Score: 93.9745 bits (232), Expect = 2.589e-20 Identity = 77/313 (24.60%), Postives = 141/313 (45.05%), Query Frame = 2
Query: 125 GFNLDLSYVTSRIIAMGFP-AEKFEALYRNDIDDVSKFFEVNHCGKYKIYNLCRERNFNASKFSGEIARFPFDDHNAPIFTDLVACVNDIAQFLDSCPDNVVAINCKAGKGRTGVIVCCTLIHCENNKDATTALQDYGKSRTLNGK--GVTIPSQIRYIFYYDHFVKNKLKYASIPLWLRKINFEMVPNI---GNAEVEYAIYRVNSQNKIXXXXXXXXXXQDRQITFVESISYPLEDDLKFQFFYKTLMGGTK------ILCQCWLNTF--FIVNQPLIQCLDPV------PRKSNSKNVFNRLPSKPPSDE 1003
G +L+L+Y+T RII++ P Y + DV++ H Y + NL ER + KF+ + F + D +AP L + + +L++ P +VV I+CK K RTGV+V + + A+ AL Y + + K ++ PSQ RY+ Y+ + ++K ++PL+L I +PN+ G IY+ + +++S Y +++ PL+ D+ + +++ T+ C + F ++ + LI+ P+ P + +F+ P KPP E
Sbjct: 10 GRDLELTYITERIISLCAPTGGDSHVAYHQQMRDVARMLHSKHANGYLVINL-SERRHDIEKFNVHVRDFGWPDLHAPPLDVLCSICKAMDSWLNADPAHVVVIHCKGNKCRTGVVVASYMYYNGICASASQALDRYAMKKFYDDKVAKLSQPSQRRYVSYFSELLSGRVKVNNLPLFLHHIVIHGLPNLEDDGGCRPFLKIYQ--AAQPLHTSAVYNIPNNCKKLCITIEPGLPLKGDILVKCYHRGCQAATRDEIFRVQFHTCVVQDFRPLVLGKSLIKSFLPLFSDEKFPDDGRVEFIFSSGPEKPPGGE 319
BLAST of Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN vs. Ensembl Sea Lamprey
Match: ENSPMAT00000005736.1 (pep scaffold:Pmarinus_7.0:GL478791:38400:53446:1 gene:ENSPMAG00000005201.1 transcript:ENSPMAT00000005736.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 87.0409 bits (214), Expect = 7.190e-19 Identity = 57/188 (30.32%), Postives = 89/188 (47.34%), Query Frame = 2
Query: 125 GFNLDLSYVTSRIIAMGFPAEKFEALYRNDIDDVSKFFEVNHCGKYKIYNLCRERNFNASKFSGEIARFPFDDHNAPIFTDLVACVNDIAQFLDSCPDNVVAINCKAGKGRTGVIVCCTLIHCENNKDATTALQDYGKSRTLNGK--GVTIPSQIRYIFYYDHFVKNKLKYASIPLWLRKINFEMVPN 682
G LDL+Y+T RIIA+ +P + Y I NL ER + K + ++ F + D +AP L + + +L++ P +VV I+CK KGRTGV+V + + A AL Y + + K V+ PSQ RY+ Y+ + K K ++PL+L I + +PN
Sbjct: 10 GQELDLTYITERIIAVSYPPGGSQLTY--------------------ILNLS-ERRHDIEKLNPQVKDFGWPDLHAPPLDILCSLCKAMDSWLNADPQHVVVIHCKGNKGRTGVVVASYMYYNSICASAHQALDRYAMKKFYDDKVAAVSQPSQKRYVTYFSELLSGKTKVNNMPLFLHHIVVQGLPN 176
BLAST of Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN vs. Ensembl Sea Lamprey
Match: ENSPMAT00000010485.1 (pep scaffold:Pmarinus_7.0:GL477590:24098:49109:-1 gene:ENSPMAG00000009496.1 transcript:ENSPMAT00000010485.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 85.1149 bits (209), Expect = 2.692e-18 Identity = 50/180 (27.78%), Postives = 84/180 (46.67%), Query Frame = 2
Query: 128 FNLDLSYVTSRIIAMGFPAEKFEALYRNDIDDVSKFFEVNHCGKYKIYNLCRERNFNASKFSGEIARFPFDDHNAPIFTDLVACVNDIAQFLDSCPDNVVAINCKAGKGRTGVIVCCTLIHCENNKDATTALQDYGKSRTLNGK--GVTIPSQIRYIFYYDHFVKNKLKYASIPLWLRKI 661
F DL+Y+T RIIA P E +++ + D++ H KY I NL RN + + ++ F + +AP L + I +L+S P +V ++C G GV++ + + A AL + R K +T PSQ RY++Y++ + +K S P++L I
Sbjct: 5 FEFDLTYITERIIATTLPPGIAEHAHQSSLRDIAGMLTSKHADKYLIINLSGRRN-EMLQLNPQVLDFGWPSRHAPHLDTLCSICKAIDSWLNSHPLHVAVLHCAGNSGSAGVVIAAFMHYSAICASADQALDRFAMKRFYVEKFASLTQPSQQRYVYYFNGLLSGSIKMNSAPVYLSHI 183
BLAST of Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN vs. Ensembl Sea Lamprey
Match: ENSPMAT00000010484.1 (pep scaffold:Pmarinus_7.0:GL477590:9709:49115:-1 gene:ENSPMAG00000009496.1 transcript:ENSPMAT00000010484.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 85.1149 bits (209), Expect = 8.735e-18 Identity = 50/180 (27.78%), Postives = 84/180 (46.67%), Query Frame = 2
Query: 128 FNLDLSYVTSRIIAMGFPAEKFEALYRNDIDDVSKFFEVNHCGKYKIYNLCRERNFNASKFSGEIARFPFDDHNAPIFTDLVACVNDIAQFLDSCPDNVVAINCKAGKGRTGVIVCCTLIHCENNKDATTALQDYGKSRTLNGK--GVTIPSQIRYIFYYDHFVKNKLKYASIPLWLRKI 661
F DL+Y+T RIIA P E +++ + D++ H KY I NL RN + + ++ F + +AP L + I +L+S P +V ++C G GV++ + + A AL + R K +T PSQ RY++Y++ + +K S P++L I
Sbjct: 7 FEFDLTYITERIIATTLPPGIAEHAHQSSLRDIAGMLTSKHADKYLIINLSGRRN-EMLQLNPQVLDFGWPSRHAPHLDTLCSICKAIDSWLNSHPLHVAVLHCAGNSGSAGVVIAAFMHYSAICASADQALDRFAMKRFYVEKFASLTQPSQQRYVYYFNGLLSGSIKMNSAPVYLSHI 185
BLAST of Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN vs. Ensembl Sea Lamprey
Match: ENSPMAT00000009584.1 (pep scaffold:Pmarinus_7.0:GL480473:6650:34123:1 gene:ENSPMAG00000008668.1 transcript:ENSPMAT00000009584.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 85.5001 bits (210), Expect = 9.073e-18 Identity = 52/189 (27.51%), Postives = 87/189 (46.03%), Query Frame = 2
Query: 131 NLDLSYVTSRIIAMGFPAEKFEALYRNDIDDVSKFFEVNHCGKYKIYNLCRERNFNASKFSGEIARFPFDDHNAPIFTDLVACVNDIAQFLDSCPDNVVAINCKAGKGRTGVIVCCTLIHCENNKDATTALQDYGKSRTLNGKGVTIPSQIRYIFYYDHFVKNKLKYASIPLWLRKINFEMVPNIGNAE 697
+LD+SY+T+R+ M +PAE E+ ++N I+DV + + H Y ++NLC +R + ++F ++ + F AP L D+ +L P N+ ++C G+ + V VC L C A AL Y R G PS R + +K+ + L + + F+M G E
Sbjct: 6 DLDISYITTRVAVMSYPAEGVESAFKNHIEDVRAYLDSRHPDHYAVFNLC-QRGYRPARFHNRVSEYAFPTRRAPNLGCLYTFCKDLLVWLKQDPKNICVVHCLDGRAVSAVAVCSFLCFCRLFSTAEAALYMYSLRRCPPG---IWPSHKRRVPAASELPNSKV----VSLKVYDVPFDMSQAKGTLE 186
BLAST of Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN vs. Ensembl Yeast
Match: TEP1 (PTEN homolog with no demonstrated inositol lipid phosphatase activity; plays a role in normal sporulation; homolog of human tumor suppressor gene PTEN/MMAC1/TEP1 and fission yeast ptn1 [Source:SGD;Acc:S000005072]) HSP 1 Score: 71.633 bits (174), Expect = 6.983e-14 Identity = 59/219 (26.94%), Postives = 92/219 (42.01%), Query Frame = 2
Query: 125 GFNLDLSYVTSRIIAMGFPAEKF-EALYRNDIDDVSKFFEVNHC-GKYKIYNLCRERNFN----------ASKFS----------------GEIARFPFD----------------------DHNAPIFTDLVACVNDIAQFLDSCPDNVVAINCKAGKGRTGVIVCCTL---IHCENNKDATTALQDYGKSRTLNGKGVTIPSQIRYIFYYDHFVKNK 622
G LD+SY+ +I +P + + LYRN +DD+ F V H G ++I+N E+ + A+KF G+I P D DH P F L V+ I +L + V ++C+ GKGR+G+I L + C + +Q K N GVTIPSQ+RY+ Y++ F+ ++
Sbjct: 39 GLRLDISYILVNLIVCSYPVNTYPKLLYRNSLDDLILFLTVYHGKGNFRIFNFRGEKEDSDYKDNDLIGIAAKFESKDFEIQELRSTLINDGKIPISPIDLETRTLVEEETNNVICERIGWLDHFPPPFELLEEIVDGIENYLSVSKNRVAVLHCRMGKGRSGMITVAYLMKYLQCPLGEARLIFMQARFKYGMTN--GVTIPSQLRYLRYHEFFITHE 255
BLAST of Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN vs. Ensembl Nematostella
Match: EDO32901 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7STQ6]) HSP 1 Score: 232.261 bits (591), Expect = 1.247e-71 Identity = 134/360 (37.22%), Postives = 208/360 (57.78%), Query Frame = 2
Query: 74 STIRTIVSKKKRRYKKQGFNLDLSYVTSRIIAMGFPAEKFEALYRNDIDDVSKFFEVNHCGKYKIYNLCRERNFNASKFSGEIARFPFDDHNAPIFTDLVACVNDIAQFLDSCPDNVVAINCKAGKGRTGVIVCCTLIHCENNKDATTALQDYGKSRTLNGKGVTIPSQIRYIFYYDHFVKNKLKYASIPLWLRKINFEMVPNI--GNAEVEYAIYRVNSQNKIXXXXXXXXXXQ-DRQITFVESISYPLEDDLKFQFFYKTLMGGTKILCQCWLNTFFIVNQPLIQCLDPVPRKSNSKNVFNRLPSKPPSDEAKCPIARPEKPHENIYTIRLTKKEIDEANKDSTFRIFPENFSITFMF 1144
S + +VSKKKRR+++ GF+LDL+Y+ I+AMGFP+EK E +YRN +D+V +F E H YK+YNLC ER ++ +F +A +PFDDHNAP F + +D+ ++L + NV I+CKAGKGRTGV++C L+H + KD A++ YG +RT N KGVTIPSQ RY+ YY + ++N L Y + LR +PN+ GN Y I++ + KI++SK +++K+ D I S P+ D+K +FF+K G + + Q W NTFFI S N+ + +P K E + ++ + K+ +D+A+KD+ ++F +F ++ +F
Sbjct: 2 SYFKQLVSKKKRRFQEDGFDLDLTYIKPNIVAMGFPSEKLEGVYRNHMDEVYRFLEQKHKDSYKVYNLCSERQYDPMRFHNRVATYPFDDHNAPPFELIKPFCDDVDEWLKASNLNVAIIHCKAGKGRTGVMICAYLLHNGHFKDTKEAMEYYGNARTRNAKGVTIPSQRRYVEYYGYLLRNCLTYVPTMVLLRGFEIITIPNMQGGNCCPFYIIWQY--KVKIHTSKLIESSKKGDTSIKLELSQPLPICGDIKVEFFHKDTFGRKERMFQFWFNTFFI---------------STGANMTDSREGEPTIHTFK------ESRNSDVRWFAIPKQFVDKAHKDNKCKVFSPDFKVSNVF 338
BLAST of Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN vs. Ensembl Nematostella
Match: EDO47071 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RN45]) HSP 1 Score: 160.999 bits (406), Expect = 1.417e-44 Identity = 74/184 (40.22%), Postives = 113/184 (61.41%), Query Frame = 2
Query: 68 MNSTIRTIVSKKKRRYKKQGFNLDLSYVTSRIIAMGFPAEKFEALYRNDIDDVSKFFEVNHCGKYKIYNLCRERNFNASKFSGEIARFPFDDHNAPIFTDLVACVNDIAQFLDSCPDNVVAINCKAGKGRTGVIVCCTLIHCENNKDATTALQDYGKSRT-----LNGKGVTIPSQIRYIFYYD 604
+ R ++S+ KRRY++ GF+LDL+YVT R+IAM FP+ +YRN I +V++F + H YK+YNLC ER+++ S F ++ R DDHN P + L+ +++ ++LD P NV+A++CK GKGRTG +C LI + A +L+ +G RT +GV PSQ RY+ Y +
Sbjct: 24 LERATRRMISQNKRRYQQDGFDLDLTYVTERVIAMSFPSSGKHKMYRNPISEVARFLDTKHSDHYKVYNLCSERSYDPSIFHNQVERILIDDHNVPRLSQLLYFCHNVREWLDKDPSNVIAVHCKGGKGRTGTAICAWLIASGQFEQAQHSLEYFGVRRTDYSVGKTYQGVQTPSQGRYVGYLE 207
BLAST of Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN vs. Ensembl Nematostella
Match: EDO45782 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RRM0]) HSP 1 Score: 138.658 bits (348), Expect = 7.585e-37 Identity = 86/282 (30.50%), Postives = 143/282 (50.71%), Query Frame = 2
Query: 89 IVSKKKRRYKKQGFNLDLSYVTSRIIAMGFPAEKFEALYRNDIDDVSKFFEVNHCGKYKIYNLCRERNFNASKFSGEIARFPFDDHNAPIFTDLVACVNDIAQFLDSCPDNVVAINCKAGKGRTGVIVCCTLIHCENNKDATTALQDYGKSRTLNGK--GVTIPSQIRYIFYYDHFVKNKLKYASIPLWLRKINFEMVPNIGNAEVEYAIYRVNSQNKIXXXXXXXXXXQDRQ-ITFVESISYPLEDDLKFQFFYK-TLMGGTKILCQCWLNTFFIVNQPLI 922
I + + R+ F+LDL+Y+T RIIAM FP E+ YRN++ DV+K + H KY ++NL ER ++ SK + ++ F + DH AP L + + I +L + P +VV ++CK GKGRTGV++ + + AL + R + K GVT PSQ RY+ Y+ +++ K+K +S P++L + +PN + RV K+ + QD + + L D+ + ++K TL I+ +C +T I + L+
Sbjct: 2 ISYRGRVRHVDHEFDLDLTYITERIIAMSFPGTGLESTYRNNLRDVAKMLQRKHQDKYMVFNLS-ERRYDISKLNHQVLDFGWPDHLAPPLERLCSIIKSIDSWLKTDPQHVVVVHCKGGKGRTGVVISAYMHFSKMCSSPEAALDWFAIKRFYDDKLGGVTQPSQRRYVHYFSDYLEGKIKLSSEPMFLHHVIVHGIPNFDSKGGCKPFLRVYDGLKLVYTSGVFLVTQDMERVCITIEGGLILHGDVLIKCYHKNTLSSVRDIIFRCQFHTGAIKDCVLV 282
BLAST of Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN vs. Ensembl Nematostella
Match: EDO43926 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RX98]) HSP 1 Score: 99.3673 bits (246), Expect = 6.156e-22 Identity = 60/190 (31.58%), Postives = 95/190 (50.00%), Query Frame = 2
Query: 131 NLDLSYVTSRIIAMGFPAEKFEALYRNDIDDVSKFFEVNHCGKYKIYNLCRERNFNASKFSGEIARFPFDDHNAPIFTDLVACVNDIAQFLDSCPDNVVAINCKAGKGRTGVIVCCTLIHCENNKDATTALQDYGKSRTLNGKGVTI-PSQIRYIFYYDHFVKN-KLKYASIPLWLRKINFEMVPNIGNA 694
+LDLSY+TSRII M FPAE E+ Y+N+IDDV +F E H +Y + N+ RN+ A K S + + + P +++ I +L V+ I+C G+ +GV+V + C+ K+ A + R G+ V + PSQ RY+ Y + N +K L+++ + VP A
Sbjct: 404 DLDLSYITSRIIVMSFPAEGIESTYKNNIDDVREFLEAKHYEQYFVVNVS-PRNYRADKLSTRVLHQCWPVNRLPPLESIISLCRKIFVWLKKDSSRVIVIHCMDGRVASGVLVSAFFVFCKLFKNPNGAADMFSIRRCGIGQKVALTPSQERYLLYIAELINNPSMKPQKNSLYIKSVTLNPVPAFNKA 592
BLAST of Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN vs. Ensembl Nematostella
Match: EDO29614 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T353]) HSP 1 Score: 53.9138 bits (128), Expect = 1.295e-9 Identity = 24/58 (41.38%), Postives = 36/58 (62.07%), Query Frame = 2
Query: 278 CRERNFNASKFSGEIARFPFDDHNAPIFTDLVACVNDIAQFLDSCPDNVVAINCKAGK 451
C ER ++ +F +A +PFDDHNAP F + +D+ ++L + NV I+CKAGK
Sbjct: 12 CSERQYDPMRFHNRVATYPFDDHNAPPFELIKPFCDDVDEWLKASNLNVAIIHCKAGK 69
BLAST of Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN vs. Ensembl Medaka
Match: ENSORLT00000040384.1 (phosphatase and tensin homolog [Source:NCBI gene;Acc:101171856]) HSP 1 Score: 248.44 bits (633), Expect = 1.557e-76 Identity = 145/374 (38.77%), Postives = 217/374 (58.02%), Query Frame = 2
Query: 68 MNSTIRTIVSKKKRRYKKQGFNLDLSYVTSRIIAMGFPAEKFEALYRNDIDDVSKFFEVNHCGKYKIYNLCRERNFNASKFSGEIARFPFDDHNAPIFTDLVACVNDIAQFLDSCPDNVVAINCKAGKGRTGVIVCCTLIHCENNKDATTALQDYGKSRTLNGKGVTIPSQIRYIFYYDHFVKNKLKYASIPLWLRKINFEMVP--NIGNAEVEYAIYRVNSQNKIXXXXXXXXXXQDRQITFVESISYPLEDDLKFQFFYKT--LMGGTKILCQCWLNTFFIVNQPLIQCLDPVPRKSNSK------NVFNRLPSKPPSDE---AKCPIARPEKPHENIYTI-RLTKKEIDEANKDSTFRIFPENFSITFMFS 1147
M + I+ +VS+ KRRY++ GF+LDL+Y+ IIAMGFPAE+ E +YRN+IDDV +F + H YKIYNLC ER+++A+KF+ +A++PF+DHN P + D+ Q+L ++V AI+CKAGKGRTGV++C L+H +A AL YG+ RT + KGVTIPSQ RY+ YY + +KN+L+Y + L K+ FE +P + G ++ +Y++ KI++S T ++D+ + F P+ D+K +FF+K +M K+ W+NTFFI P P +S + N PS P + A+C E + Y I L K ++D+ANKD R F NF + F+
Sbjct: 1 MAAIIKEMVSRNKRRYQEDGFDLDLTYIYPNIIAMGFPAERLEGVYRNNIDDVVRFLDSKHKNHYKIYNLCAERHYDAAKFNCRVAQYPFEDHNPPQLELIKPFCEDLDQWLSEDDNHVAAIHCKAGKGRTGVMICAYLLHRGKFLEAQEALDFYGEVRTRDKKGVTIPSQRRYVCYYSYLLKNQLEYKPVALLFHKMVFETLPMFSGGTCNPQFVVYQLKV--KIHTSNPLHTRREDKHMYFEFPQPLPVCGDIKVEFFHKQNKMMKKDKMF-HFWVNTFFI----------PGPEESGDRMENGSVNDAESQPSGPGQGQPQNAECRDGCREGDRDRDYLILTLNKNDLDKANKDKANRYFSPNFKVKLYFT 361
BLAST of Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN vs. Ensembl Medaka
Match: PTEN (phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [Source:NCBI gene;Acc:101173689]) HSP 1 Score: 246.514 bits (628), Expect = 1.056e-75 Identity = 142/372 (38.17%), Postives = 218/372 (58.60%), Query Frame = 2
Query: 80 IRTIVSKKKRRYKKQGFNLDLSYVTSRIIAMGFPAEKFEALYRNDIDDVSKFFEVNHCGKYKIYNLCRERNFNASKFSGEIARFPFDDHNAPIFTDLVACVNDIAQFLDSCPDNVVAINCKAGKGRTGVIVCCTLIHCENNKDATTALQDYGKSRTLNGKGVTIPSQIRYIFYYDHFVKNKLKYASIPLWLRKINFEMVP--NIG-----------NAEVEYAIYRVNSQNKIXXXXXXXXXXQDRQITFVESISYPLEDDLKFQFFYKT--LMGGTKILCQCWLNTFFIVNQPLIQCLDPVPRKSNSKNVFNRLPSKPPSDEAKCPIARPEKPHE-NIYTIRLTKKEIDEANKDSTFRIFPENFSITFMFS 1147
I+ IVS+ KRR+++ GF+LDL+Y+ IIAMGFPAE+ E +YRN+IDDV +F + H YKIYNLC ER+++ +KF+ +A++PF+DHN P + D+ Q+L +V AI+CKAGKGRTGV++C L+H ++A AL YG+ RT + KGVTIPSQ RY+ YY++ +KN+L+Y + L K+ FE VP +G +A ++ +Y++ + KI++S T ++D+ + F P+ D+K +FF+K +M K+ W+NTFFI P P +++ K + P SD + P ++ + + LTK E+D+ANKD + F NF + FS
Sbjct: 6 IKEIVSRNKRRFQEDGFDLDLTYIYPNIIAMGFPAERLEGVYRNNIDDVVRFLDSKHKNHYKIYNLCAERHYDTTKFNCRVAQYPFEDHNPPQLELIKPFCEDLDQWLSENEHHVAAIHCKAGKGRTGVMICAYLLHRGKFREAQEALDFYGEVRTRDKKGVTIPSQRRYVVYYNYLLKNRLQYKPVALLFHKMMFETVPMFTVGTCSESGSGPPLHAHPQFVVYQL--KVKIHTSNPAHTRREDKLLLFEFPQPLPVCGDIKVEFFHKQNKVMKKEKMF-HFWINTFFI----------PGPEEASYK--LENGSAAPNSDVSDRTYQNPGDANDKDFLVLTLTKNELDKANKDKANKNFSPNFKVRLFFS 362
BLAST of Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN vs. Ensembl Medaka
Match: ENSORLT00000007833.2 (phosphatase and tensin homolog [Source:NCBI gene;Acc:101171856]) HSP 1 Score: 239.58 bits (610), Expect = 7.912e-73 Identity = 144/395 (36.46%), Postives = 216/395 (54.68%), Query Frame = 2
Query: 68 MNSTIRTIVSKKKRRYKKQGFNLDLSYVTSRIIAMGFPAEKFEALYRNDIDDVSKFFEVNHCGKYKIYNLCRERNFNASKFSGEIARFPFDDHNAPIFTDLVACVNDIAQFLDSCPDNVVAINCKAGKGRTGVIVCCTLIHCENNKDATTALQDYGKSRTLNGKGVTIPSQIRYIFYYDHFVKNKLKYASIPLWLRKINFEMVPNIGNA-----------------------EVEYAIYRVNSQNKIXXXXXXXXXXQDRQITFVESISYPLEDDLKFQFFYKT--LMGGTKILCQCWLNTFFIVNQPLIQCLDPVPRKSNSK------NVFNRLPSKPPSDE---AKCPIARPEKPHENIYTI-RLTKKEIDEANKDSTFRIFPENFSITFMFS 1147
M + I+ +VS+ KRRY++ GF+LDL+Y+ IIAMGFPAE+ E +YRN+IDDV +F + H YKIYNLC ER+++A+KF+ +A++PF+DHN P + D+ Q+L ++V AI+CKAGKGRTGV++C L+H +A AL YG+ RT + KGVTIPSQ RY+ YY + +KN+L+Y + L K+ FE +P + ++ +Y++ KI++S T ++D+ + F P+ D+K +FF+K +M K+ W+NTFFI P P +S + N PS P + A+C E + Y I L K ++D+ANKD R F NF + F+
Sbjct: 1 MAAIIKEMVSRNKRRYQEDGFDLDLTYIYPNIIAMGFPAERLEGVYRNNIDDVVRFLDSKHKNHYKIYNLCAERHYDAAKFNCRVAQYPFEDHNPPQLELIKPFCEDLDQWLSEDDNHVAAIHCKAGKGRTGVMICAYLLHRGKFLEAQEALDFYGEVRTRDKKGVTIPSQRRYVCYYSYLLKNQLEYKPVALLFHKMVFETLPMFSGGTCRDVKNRSEPTPQGFKKGNWHWDPQFVVYQLKV--KIHTSNPLHTRREDKHMYFEFPQPLPVCGDIKVEFFHKQNKMMKKDKMF-HFWVNTFFI----------PGPEESGDRMENGSVNDAESQPSGPGQGQPQNAECRDGCREGDRDRDYLILTLNKNDLDKANKDKANRYFSPNFKVKLYFT 382
BLAST of Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN vs. Ensembl Medaka
Match: ENSORLT00000007829.2 (phosphatase and tensin homolog [Source:NCBI gene;Acc:101171856]) HSP 1 Score: 191.045 bits (484), Expect = 1.336e-54 Identity = 132/395 (33.42%), Postives = 198/395 (50.13%), Query Frame = 2
Query: 89 IVSKKKRRYKKQGFNLDLSYVTSRIIAMGFPAEKFEALYRNDIDDV-------SKFFEVNHCGKYKIYNLCRERNFNASKFSGEIARFPFDDHNAPIFTDLVACVNDIAQFLDSCPDNVVAINCKAGKGRTGVIVCCTLIHCENNKDATTALQDYGKSRTLNGKGVTIPSQIRYIFYYDHFVKNKLKYASIPLWLRKINFEMVPNIGNA-----------------------EVEYAIYRVNSQNKIXXXXXXXXXXQDRQITFVESISYPLEDDLKFQFFYKT--LMGGTKILCQCWLNTFFIVNQPLIQCLDPVPRKSNSK------NVFNRLPSKPPSDE---AKCPIARPEKPHENIYTI-RLTKKEIDEANKDSTFRIFPENFSITFMFS 1147
+VS+ KRRY++ GF+LDL+Y+ IIAMGFPAE+ E +YRN+IDDV + V+ Y + R S +A++PF+DHN P + D+ Q+L ++V AI+CKAGKGRTGV++C L+H +A AL YG+ RT + KGVTIPSQ RY+ YY + +KN+L+Y + L K+ FE +P + ++ +Y++ KI++S T ++D+ + F P+ D+K +FF+K +M K+ W+NTFFI P P +S + N PS P + A+C E + Y I L K ++D+ANKD R F NF + F+
Sbjct: 1 MVSRNKRRYQEDGFDLDLTYIYPNIIAMGFPAERLEGVYRNNIDDVLFKSLMITPLLFVSTYYYYYFISFTTLRGLACRHAS--VAQYPFEDHNPPQLELIKPFCEDLDQWLSEDDNHVAAIHCKAGKGRTGVMICAYLLHRGKFLEAQEALDFYGEVRTRDKKGVTIPSQRRYVCYYSYLLKNQLEYKPVALLFHKMVFETLPMFSGGTCRDVKNRSEPTPQGFKKGNWHWDPQFVVYQLKV--KIHTSNPLHTRREDKHMYFEFPQPLPVCGDIKVEFFHKQNKMMKKDKMF-HFWVNTFFI----------PGPEESGDRMENGSVNDAESQPSGPGQGQPQNAECRDGCREGDRDRDYLILTLNKNDLDKANKDKANRYFSPNFKVKLYFT 380
BLAST of Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN vs. Ensembl Medaka
Match: tpte (phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase TPTE2 [Source:NCBI gene;Acc:101172265]) HSP 1 Score: 168.703 bits (426), Expect = 4.920e-46 Identity = 81/218 (37.16%), Postives = 128/218 (58.72%), Query Frame = 2
Query: 68 MNSTIRTIVSKKKRRYKKQGFNLDLSYVTSRIIAMGFPAEKFEALYRNDIDDVSKFFEVNHCGKYKIYNLCRERNFNASKFSGEIARFPFDDHNAPIFTDLVACVNDIAQFLDSCPDNVVAINCKAGKGRTGVIVCCTLIHCENNKDATTALQDYG-----KSRTLNGKGVTIPSQIRYIFYYDHFVKNKLKYASIP---LWLRKINFEMVPNIGNAE 697
+ R ++S+ KRRY+K GF+LDL+YVT R+IAM FP+ +A YRN I +V++F + H G YK++NLC E+ ++ F + R DDHN P D++ + +++ + P NV+AI+CK GKGRTG +VC LI + + A +L+ +G K+R+ +GV PSQ RY+ YY+ +KNK P L ++ + + +G +
Sbjct: 138 LEKVTRRMISENKRRYQKDGFDLDLTYVTDRVIAMSFPSSGKQAFYRNPIKEVARFLDTKHEGHYKVFNLCSEKGYDPQHFHYRVERVFIDDHNVPALEDMLKFTASVREWMSADPQNVIAIHCKGGKGRTGTMVCTWLIDSDQFESAQDSLEYFGERRTDKTRSSKFQGVETPSQSRYVGYYE-VMKNKFNRQLPPPQSLRIKSLRIHSIAGVGRGD 354
BLAST of Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN vs. Planmine SMEST
Match: SMESG000072902.1 (SMESG000072902.1) HSP 1 Score: 800.431 bits (2066), Expect = 0.000e+0 Identity = 410/410 (100.00%), Postives = 410/410 (100.00%), Query Frame = 2
Query: 68 MNSTIRTIVSKKKRRYKKQGFNLDLSYVTSRIIAMGFPAEKFEALYRNDIDDVSKFFEVNHCGKYKIYNLCRERNFNASKFSGEIARFPFDDHNAPIFTDLVACVNDIAQFLDSCPDNVVAINCKAGKGRTGVIVCCTLIHCENNKDATTALQDYGKSRTLNGKGVTIPSQIRYIFYYDHFVKNKLKYASIPLWLRKINFEMVPNIGNAEVEYAIYRVNSQNKIXXXXXXXXXXQDRQITFVESISYPLEDDLKFQFFYKTLMGGTKILCQCWLNTFFIVNQPLIQCLDPVPRKSNSKNVFNRLPSKPPSDEAKCPIARPEKPHENIYTIRLTKKEIDEANKDSTFRIFPENFSITFMFSDCPLNTDXXXXXXXXXXXXTFFGNRDSENLVSQLETMWDINSSDFHGSLD 1297
MNSTIRTIVSKKKRRYKKQGFNLDLSYVTSRIIAMGFPAEKFEALYRNDIDDVSKFFEVNHCGKYKIYNLCRERNFNASKFSGEIARFPFDDHNAPIFTDLVACVNDIAQFLDSCPDNVVAINCKAGKGRTGVIVCCTLIHCENNKDATTALQDYGKSRTLNGKGVTIPSQIRYIFYYDHFVKNKLKYASIPLWLRKINFEMVPNIGNAEVEYAIYRVNSQNKIYSSKTYKTTKQDRQITFVESISYPLEDDLKFQFFYKTLMGGTKILCQCWLNTFFIVNQPLIQCLDPVPRKSNSKNVFNRLPSKPPSDEAKCPIARPEKPHENIYTIRLTKKEIDEANKDSTFRIFPENFSITFMFSDCPLNTDNNGNSLISIGNSTFFGNRDSENLVSQLETMWDINSSDFHGSLD
Sbjct: 1 MNSTIRTIVSKKKRRYKKQGFNLDLSYVTSRIIAMGFPAEKFEALYRNDIDDVSKFFEVNHCGKYKIYNLCRERNFNASKFSGEIARFPFDDHNAPIFTDLVACVNDIAQFLDSCPDNVVAINCKAGKGRTGVIVCCTLIHCENNKDATTALQDYGKSRTLNGKGVTIPSQIRYIFYYDHFVKNKLKYASIPLWLRKINFEMVPNIGNAEVEYAIYRVNSQNKIYSSKTYKTTKQDRQITFVESISYPLEDDLKFQFFYKTLMGGTKILCQCWLNTFFIVNQPLIQCLDPVPRKSNSKNVFNRLPSKPPSDEAKCPIARPEKPHENIYTIRLTKKEIDEANKDSTFRIFPENFSITFMFSDCPLNTDNNGNSLISIGNSTFFGNRDSENLVSQLETMWDINSSDFHGSLD 410
BLAST of Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN vs. Planmine SMEST
Match: SMESG000043909.1 (SMESG000043909.1) HSP 1 Score: 320.472 bits (820), Expect = 8.361e-104 Identity = 174/384 (45.31%), Postives = 240/384 (62.50%), Query Frame = 2
Query: 68 MNSTIRTIVSKKKRRYKKQGFNLDLSYVTSRIIAMGFPAEKFEALYRNDIDDVSKFFEVNHCGKYKIYNLCRERNFNASKFSGEI--ARFPFDDHNAPIFTDLVACVNDIAQFLDSCPDNVVAINCKAGKGRTGVIVCCTLIHCENNKDATTALQDYGKSRTLNGKGVTIPSQIRYIFYYDHFVKNKLKYASIPLWLRKINFEMVPNI-GNA-EVEYAIY---RVNSQNKIXXXXXXXXXXQD--RQITFVESISYPLEDDLKFQFFYKTLMGGTKILCQCWLNTFFIVNQPLIQCL-DPVPRKSNSKNVFNRLPSKPP------SDEAKCPIARPEKPHEN---IYTIRLTKKEIDEANKDSTFRIFPENFSITFMFSDCPLN 1162
M + ++ +VSKKK RY + GF+LDLSY+TSRIIAMGFPA+ +E +YRN IDDV FF H Y+IYNLC ER+ + KF ++PF+DHN P+FT ++ C +I +LDS P+N+VAI CKAGKGRTGVIVC L+ E +K AT LQ YG+ RT NGKGVTIPSQIR+I+Y++HF++ +LKY L L + + +P I GN E+++ IY R Q K++ + + ++D R + + + + DDLKFQF K+ G + LC CWLNTFFIV++P IQ D + SNS V K P SDE+K + + ++ +Y +RL K EID+A KD + FP F+ITF+F + N
Sbjct: 1 MPNKLKELVSKKKIRYVQDGFDLDLSYITSRIIAMGFPAQSWEGIYRNHIDDVVNFFHKKHANHYQIYNLCNERHIDEQKFEHNSINHQYPFNDHNPPMFTQMIECCKEIQDYLDSDPNNIVAIQCKAGKGRTGVIVCACLLSQEPDKSATDILQFYGERRTTNGKGVTIPSQIRFIYYFEHFLRKELKYEKTVLKLNHVVLDEMPIISGNGYEIQFVIYIYDREAKQLKVHHTSQFYEARKDGARSLNLLSDECFIVSDDLKFQFILKSKFGKKENLCHCWLNTFFIVHKPQIQSFQDGIKHNSNSNKVGKSAGRKGPRFTSDNSDESKTDFSHAQSDSDSQPFLYKLRLQKHEIDKACKDLNNKTFPSTFAITFVFENYHFN 384
BLAST of Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN vs. Planmine SMEST
Match: SMESG000060206.1 (SMESG000060206.1) HSP 1 Score: 155.606 bits (392), Expect = 3.019e-41 Identity = 77/184 (41.85%), Postives = 111/184 (60.33%), Query Frame = 2
Query: 83 RTIVSKKKRRYKKQGFNLDLSYVTSRIIAMGFPAEKFEALYRNDIDDVSKFFEVNHCGKYKIYNLCRERNFNASKFSGEIARFPFDDHNAPIFTDLVACVNDIAQFLDSCPDNVVAINCKAGKGRTGVIVCCTLIHCENNKDATTALQDYGKSRT--LNGK---GVTIPSQIRYIFYYDHFVKN 619
R + S+ KRR++ G++LDL YVT R+IAM FP+ F ALYRN I DV+KFF + YKIYNLC ER ++ F+ ++ R+ DHN P +++ ++L N++A++CK GKGRTG ++C LI +A LQ +G+ RT L GK GV PSQ RY+ Y++ K+
Sbjct: 154 RHVTSENKRRFQSGGYDLDLCYVTDRVIAMSFPSSGFTALYRNSITDVAKFFNSKYGSNYKIYNLCEERAYDTKIFNDQVERYMVKDHNVPRLEEILEFAKSSREWLTKSDQNIIAVHCKGGKGRTGTMICVHLIDSGVFDNAELCLQYFGQRRTDLLQGKKFQGVETPSQNRYVGYFETIKKS 337
BLAST of Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN vs. Planmine SMEST
Match: SMESG000081891.1 (SMESG000081891.1) HSP 1 Score: 76.6406 bits (187), Expect = 2.966e-14 Identity = 62/192 (32.29%), Postives = 93/192 (48.44%), Query Frame = 2
Query: 131 NLDLSYVTSRIIAMGFPAEK-FEALYRNDIDDVSKFFEVNHCGKYKIYNLCRERNFNASKFSGEIARFPFDDHNAPIFTDLVA-CVNDIAQFLDSCPDNVVAINCKAGKGRTGVIVCCTLIHCENNKDATTALQDYGKSRTLNGKGVTIPSQIRYIFY---YDHFVKNKLKYASIP----LWLRKINFEMVP 679
+L+++YVTSRII M P E +AL R+ I+DV F + H +Y IYNL R+ +F+ + + FD F +LV+ C++ ++ L NV+ I C G+ +G+ V L C D ++A + K R G SQ+RYI Y H + N+ IP + L I E VP
Sbjct: 459 DLNITYVTSRIIMMPTPGESGIDALTRDKIEDVQTFLDFRHPNQYYIYNLSL-RSIKTERFNDRVMQLGFDSMKPMSFNNLVSVCIHQLSWLLADA-KNVIVIQCTDGRIGSGLNVAALLCFCR-LVDTSSAAVNIVKFR--RGDCQFTSSQLRYIDYICRLMHNISNQSIGPEIPHKFIVKLTGIELEPVP 645 The following BLAST results are available for this feature:
BLAST of Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 3
BLAST of Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 1
BLAST of Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 4
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30018369 ID=SMED30018369|Name=Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN|organism=Schmidtea mediterranea sexual|type=transcript|length=1645bpback to top protein sequence of SMED30018369-orf-1 >SMED30018369-orf-1 ID=SMED30018369-orf-1|Name=SMED30018369-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=411bp MNSTIRTIVSKKKRRYKKQGFNLDLSYVTSRIIAMGFPAEKFEALYRNDIback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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