Voltage-dependent T-type calcium channel subunit alpha
Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30018324 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 10
Homology
BLAST of Voltage-dependent T-type calcium channel subunit alpha vs. Ensembl Human
Match: CACNA1H (calcium voltage-gated channel subunit alpha1 H [Source:HGNC Symbol;Acc:HGNC:1395]) HSP 1 Score: 661.374 bits (1705), Expect = 0.000e+0 Identity = 397/618 (64.24%), Postives = 489/618 (79.13%), Query Frame = 1 Query: 3820 RYYHSLYVFSVDNQFRQKCQHIVDKKSFDYLVLFFITLNCITLAMERPSIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKFYYCDGPHLQAVKTKNDCLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFHKCQENQXXXXXXXXXXXXXXXXXXXXXHLRAPLYWENYSKWRRTINSVVTSKYFDLAIAGVIGLNVITMATEFHMMPQVLKTALKVFNYFFTSTFVXXXXXXXXXXXXXRYISDKWNQLDMMIVILSIAGVVIDEVE-SNFMPINPTIMRVMRVLRIARVLKLLKMASGIRALLDTVIQALPQVGNXXXXXXXXXXXXXXXXVELFGRLECSDINPCVGLGRHAHFENFGMAFLTLFRIATGDNWNGIMKDTLREKCISSEDCQRNCCVSAIIA--PIYFVIFXXXXXXXXXXXXXXXXXKHLEESHKMMCDDYELEREVQRDLDE 5664 R +LY+FS N+FR CQ ++ K FD++VL FI LNC+T+A+ERP I P S ER+FL+V+NYIFT IF EM++KV++ GLL G+ AYL+S WN++DG LV +SL+D+ + + +I G+LRV RLLRTLRPLRVISRAPGLKLVV+TL+SSLRPIGNIVLICC FFIIFGILGVQLFKGKFYYC+GP + + TK C + + W +KYNFDNLGQALM+LFVLSSKDGWV IMY G+DAVGV+ QP +NHN W L+YFISFLL+V+FFVLNMFVGVVVENFHKC+++QE EE RR KR RRLE++R+ + Y+ +YS RR+I+S+ TS Y DL I +I +NVITM+ E + P+ L ALK NY FT FV EA LKLVA G R+ D+WNQLD+ IV+LS+ G+ ++E+E S +PINPTI+R+MRVLRIARVLKLLKMA+G+RALLDTV+QALPQVGNLGLLF LLF+I+AALGVELFGRLECS+ NPC GL RHA F NFGMAFLTLFR++TGDNWNGIMKDTLRE S ED C+S + A P+YFV FVL+AQFVLVNVVVAVLMKHLEES+K +D EL+ E++ ++ + Sbjct: 11 REAWALYLFSPQNRFRVSCQKVITHKMFDHVVLVFIFLNCVTIALERPDIDPGSTERVFLSVSNYIFTAIFVAEMMVKVVALGLLSGEHAYLQSSWNLLDGLLVLVSLVDIVVAMASAGGAKILGVLRVLRLLRTLRPLRVISRAPGLKLVVETLISSLRPIGNIVLICCAFFIIFGILGVQLFKGKFYYCEGPDTRNISTKAQC-RAAHYRWVRRKYNFDNLGQALMSLFVLSSKDGWVNIMYDGLDAVGVDQQPVQNHNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHKCRQHQEAEEARRREEKRLRRLERRRRKAQRRPYYADYSPTRRSIHSLCTSHYLDLFITFIICVNVITMSMEHYNQPKSLDEALKYCNYVFTIVFVFEAALKLVAFGFRRFFKDRWNQLDLAIVLLSLMGITLEEIEMSAALPINPTIIRIMRVLRIARVLKLLKMATGMRALLDTVVQALPQVGNLGLLFMLLFFIYAALGVELFGRLECSEDNPCEGLSRHATFSNFGMAFLTLFRVSTGDNWNGIMKDTLRE--CSREDKH---CLSYLPALSPVYFVTFVLVAQFVLVNVVVAVLMKHLEESNKEAREDAELDAEIELEMAQ 622 HSP 2 Score: 82.8037 bits (203), Expect = 6.484e-15 Identity = 60/234 (25.64%), Postives = 117/234 (50.00%), Query Frame = 1 Query: 2101 PFNKNQNKTKRKNYLSICQQKIKTLVNDVKFQRGILIAILINTLSMGIEYHQQPVQLTQTLEFSNIVFSILFLIEMILKLIGEGILGYIKNGFNLFDGIIVVLGVIELCQQG---------GTSGLSILRTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKFCTIENNKRTCDR-KNFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTS 2772 P+ + + T+R + S+C L I I +N ++M +E++ QP L + L++ N VF+I+F+ E LKL+ G + K+ +N D IV+L ++ + + + + I+R R+ R+LKL++ +R L +++ + V L +L FI++ LG+ LFG C+ +N R F + + +T+F++ T ++WN ++ + + S Sbjct: 334 PYYADYSPTRRSIH-SLCTSHYLDLF--------ITFIICVNVITMSMEHYNQPKSLDEALKYCNYVFTIVFVFEAALKLVAFGFRRFFKDRWNQLDLAIVLLSLMGITLEEIEMSAALPINPTIIRIMRVLRIARVLKLLKMATGMRALLDTVVQALPQVGNLGLLFMLLFFIYAALGVELFGRLECSEDNPCEGLSRHATFSNFGMAFLTLFRVSTGDNWNGIMKDTLRECS 558 HSP 3 Score: 68.9366 bits (167), Expect = 1.003e-10 Identity = 61/282 (21.63%), Postives = 132/282 (46.81%), Query Frame = 1 Query: 2134 KNYLSICQQKIKTLVNDVKFQRGILIAILINTLSMGIEYHQQPVQLTQT--LEFSNIVFSILFLIEMILKLIGEGIL----GYIKNGFNLFDGIIVVLGVIELCQQGGTSGLSILRTFRLLRILKL-------VRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKFCTIE-------NNKRTCD---------RKNFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTS----------SWAALYFIALMTFGNYVLFNLLVAILVEGF 2862 +N + QK+ + F +L+ I +N +++ +E T+ L SN +F+ +F+ EM++K++ G+L Y+++ +NL DG++V++ ++++ ++G + + + L + P L+ + +I ++ + + F IF ILG+ LF KF E + K C + NFD+L +++++F + +++ W ++Y+G+ W LYFI+ + ++ + N+ V ++VE F Sbjct: 22 QNRFRVSCQKV---ITHKMFDHVVLVFIFLNCVTIALERPDIDPGSTERVFLSVSNYIFTAIFVAEMMVKVVALGLLSGEHAYLQSSWNLLDGLLVLVSLVDIVVAMASAGGAKILGVLRVLRLLRTLRPLRVISRAPGLKLVVETLISSLRPIGNIVLICCAFFIIFGILGVQLFKGKFYYCEGPDTRNISTKAQCRAAHYRWVRRKYNFDNLGQALMSLFVLSSKDGWVNIMYDGLDAVGVDQQPVQNHNPWMLLYFISFLLIVSFFVLNMFVGVVVENF 300 HSP 4 Score: 65.0846 bits (157), Expect = 1.616e-9 Identity = 33/112 (29.46%), Postives = 63/112 (56.25%), Query Frame = 1 Query: 328 ATVFHIFHQNKHPRDWCLKIITWPWFEQLSMTIIAVNCITLSMYQPCGDQNCETSKCQIMQAFDYIIFAFFTCEMVIKIIAMGFL-GDLGYFGDTWNRLDMFIVIVGSIEIL 660 A ++F R C K+IT F+ + + I +NC+T+++ +P D + +++ + +YI A F EM++K++A+G L G+ Y +WN LD +V+V ++I+ Sbjct: 13 AWALYLFSPQNRFRVSCQKVITHKMFDHVVLVFIFLNCVTIALERP--DIDPGSTERVFLSVSNYIFTAIFVAEMMVKVVALGLLSGEHAYLQSSWNLLDGLLVLVSLVDIV 122 HSP 5 Score: 54.6842 bits (130), Expect = 2.327e-6 Identity = 26/80 (32.50%), Postives = 48/80 (60.00%), Query Frame = 1 Query: 1195 NFDNIGFAWVAIFQVISMESWVDIMYYVQDA----------HSFWDWIYFVALIIIGSFFMINLCLVVIASQFSETKRRE 1404 NFDN+G A +++F + S + WV+IMY DA H+ W +YF++ ++I SFF++N+ + V+ F + ++ + Sbjct: 228 NFDNLGQALMSLFVLSSKDGWVNIMYDGLDAVGVDQQPVQNHNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHKCRQHQ 307
BLAST of Voltage-dependent T-type calcium channel subunit alpha vs. Ensembl Human
Match: CACNA1H (calcium voltage-gated channel subunit alpha1 H [Source:HGNC Symbol;Acc:HGNC:1395]) HSP 1 Score: 658.292 bits (1697), Expect = 0.000e+0 Identity = 411/676 (60.80%), Postives = 507/676 (75.00%), Query Frame = 1 Query: 3667 REKALEEPDDSNSESQNSSRMNNVEDPDEEDMEAMICLSKCCPQPKGIFAKRYYHSLYVFSVDNQFRQKCQHIVDKKSFDYLVLFFITLNCITLAMERPSIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKFYYCDGPHLQAVKTKNDCLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFHKCQENQXXXXXXXXXXXXXXXXXXXXXHLRAPLYWENYSKWRRTINSVVTSKYFDLAIAGVIGLNVITMATEFHMMPQVLKTALKVFNYFFTSTFVXXXXXXXXXXXXXRYISDKWNQLDMMIVILSIAGVVIDEVE-SNFMPINPTIMRVMRVLRIARVLKLLKMASGIRALLDTVIQALPQVGNXXXXXXXXXXXXXXXXVELFGRLECSDINPCVGLGRHAHFENFGMAFLTLFRIATGDNWNGIMKDTLREKCISSEDCQRNCCVSAIIA--PIYFVIFXXXXXXXXXXXXXXXXXKHLEESHKMMCDDYELEREVQRDLDEEAKELAR 5685 RE A E DDS E R++ V +P + C S R +LY+FS N+FR CQ ++ K FD++VL FI LNC+T+A+ERP I P S ER+FL+V+NYIFT IF EM++KV++ GLL G+ AYL+S WN++DG LV +SL+D+ + + +I G+LRV RLLRTLRPLRVISRAPGLKLVV+TL+SSLRPIGNIVLICC FFIIFGILGVQLFKGKFYYC+GP + + TK C + + W +KYNFDNLGQALM+LFVLSSKDGWV IMY G+DAVGV+ QP +NHN W L+YFISFLL+V+FFVLNMFVGVVVENFHKC+++QE EE RR KR RRLE++R+ + Y+ +YS RR+I+S+ TS Y DL I +I +NVITM+ E + P+ L ALK NY FT FV EA LKLVA G R+ D+WNQLD+ IV+LS+ G+ ++E+E S +PINPTI+R+MRVLRIARVLKLLKMA+G+RALLDTV+QALPQVGNLGLLF LLF+I+AALGVELFGRLECS+ NPC GL RHA F NFGMAFLTLFR++TGDNWNGIMKDTLRE S ED C+S + A P+YFV FVL+AQFVLVNVVVAVLMKHLEES+K +D EL+ E++ ++ + R Sbjct: 1236 REDAAELDDDS--EDSCCLRLHKVLEP----YKPQWCRS------------REAWALYLFSPQNRFRVSCQKVITHKMFDHVVLVFIFLNCVTIALERPDIDPGSTERVFLSVSNYIFTAIFVAEMMVKVVALGLLSGEHAYLQSSWNLLDGLLVLVSLVDIVVAMASAGGAKILGVLRVLRLLRTLRPLRVISRAPGLKLVVETLISSLRPIGNIVLICCAFFIIFGILGVQLFKGKFYYCEGPDTRNISTKAQC-RAAHYRWVRRKYNFDNLGQALMSLFVLSSKDGWVNIMYDGLDAVGVDQQPVQNHNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHKCRQHQEAEEARRREEKRLRRLERRRRKAQRRPYYADYSPTRRSIHSLCTSHYLDLFITFIICVNVITMSMEHYNQPKSLDEALKYCNYVFTIVFVFEAALKLVAFGFRRFFKDRWNQLDLAIVLLSLMGITLEEIEMSAALPINPTIIRIMRVLRIARVLKLLKMATGMRALLDTVVQALPQVGNLGLLFMLLFFIYAALGVELFGRLECSEDNPCEGLSRHATFSNFGMAFLTLFRVSTGDNWNGIMKDTLRE--CSREDKH---CLSYLPALSPVYFVTFVLVAQFVLVNVVVAVLMKHLEESNKEAREDAELDAEIELEMAQGPGSARR 1887 HSP 2 Score: 372.474 bits (955), Expect = 2.988e-103 Identity = 237/451 (52.55%), Postives = 306/451 (67.85%), Query Frame = 1 Query: 313 YHGFYATVFHIFHQNKHPRDWCLKIITWPWFEQLSMTIIAVNCITLSMYQPCGDQNCETSKCQIMQAFDYIIFAFFTCEMVIKIIAMGFLGDLGYFGDTWNRLDMFIVIVGSIEILPSTGNNIGLTAIRTIRVLRPLRAINRIPSMRIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQMWQGVLRNRCYL------NLNESFRHPGLNLSSFYQINRTLFLNAVDKDFICSTDKNNGILKCSDIPPSIMLLSNNSL--QICKQPARPFTDNLPTKHSCVNWNQYYTDCQPGEKNPYEGAINFDNIGFAWVAIFQVISMESWVDIMYYVQDAHSFWDWIYFVALIIIGSFFMINLCLVVIASQFSETKRRETERMWIERRRFNSSNCSSISKDEPQTCYLEXXXXXXXXXXXXYRRIVKLYNQIQIRHSK-----TAQGNYQNKLKRQRK 1626 Y ATVF Q PR WCL+++ PWFE +SM +I +NC+TL M++PC D C + +C I++AFD IFAFF EMVIK++A+G G Y GDTWNRLD FIV+ G +E G+N+ L+AIRT+RVLRPLRAINR+PSMRILV LLLDTLPMLGNVLLLCFFVFFIFGI+GVQ+W G+LRNRC+L N N +F P +YQ + FICS+ ++NG+ KCS IP L +L + QP +++C+NWNQYY C+ G+ NP+ GAINFDNIG+AW+AIFQVI++E WVDIMYYV DAHSF+++IYF+ LII+GSFFMINLCLVVIA+QFSETK+RE++ M +R R S++ + S EP +CY E++K + I K+ RR ++LY + Q R K QG Q RQR+ Sbjct: 72 YPALAATVFFCLGQTTRPRSWCLRLVCNPWFEHVSMLVIMLNCVTLGMFRPCEDVECGSERCNILEAFDAFIFAFFAVEMVIKMVALGLFGQKCYLGDTWNRLDFFIVVAGMMEYS-LDGHNVSLSAIRTVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAGLLRNRCFLDSAFVRNNNLTFLRP------YYQTE-----EGEENPFICSSRRDNGMQKCSHIPGRRELRMPCTLGWEAYTQPQAEGVGA--ARNACINWNQYYNVCRSGDSNPHNGAINFDNIGYAWIAIFQVITLEGWVDIMYYVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQRESQLMREQRARHLSNDSTLASFSEPGSCYEELLKYVGHIFRKVKRRSLRLYARWQSRWRKKVDPSAVQG--QGPGHRQRR 506 HSP 3 Score: 337.806 bits (865), Expect = 1.792e-92 Identity = 189/320 (59.06%), Postives = 237/320 (74.06%), Query Frame = 1 Query: 2161 KIKTLVNDVKFQRGILIAILINTLSMGIEYHQQPVQLTQTLEFSNIVFSILFLIEMILKLIGEGILGYIKNGFNLFDGIIVVLGVIELCQQGGTSGLSILRTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKFCTIENNKRTC-DRKNFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTSSWAALYFIALMTFGNYVLFNLLVAILVEGFSSER------LDEQKLLHNYRQSLKKRRANNKQLRIMQHQSENLVLLTNSIQKDQTGENQKISSQPPVIIHTAATPMPTPRSSPY 3099 K++ +V+ F RGI++AIL+NTLSMG+EYH+QP +LT LE SNIVF+ +F +EM+LKL+ G LGYI+N +N+FDGIIVV+ V E+ Q GLS+LRTFRLLR+LKLVRF+PALR+QL V+++T+DNVATF LL+LFIFIFSILGM LFGCKF + T DRKNFDSLLW+IVTVFQILTQEDWN VLYNGM TSSWAALYF+ALMTFGNYVLFNLLVAILVEGF +E DE K ++ + K R + Q+ L + + ++ + E + S PP+I+ TAATPMPTP+SSP+ Sbjct: 785 KLRRIVDSKYFSRGIMMAILVNTLSMGVEYHEQPEELTNALEISNIVFTSMFALEMLLKLLACGPLGYIRNPYNIFDGIIVVISVWEIVGQA-DGGLSVLRTFRLLRVLKLVRFLPALRRQLVVLVKTMDNVATFCTLLMLFIFIFSILGMHLFGCKFSLKTDTGDTVPDRKNFDSLLWAIVTVFQILTQEDWNVVLYNGMASTSSWAALYFVALMTFGNYVLFNLLVAILVEGFQAEGDANRSDTDEDKTSVHFEEDFHKLR---------ELQTTELKMCSLAVTPNGHLEGRG-SLSPPLIMCTAATPMPTPKSSPF 1093 HSP 4 Score: 112.464 bits (280), Expect = 9.012e-24 Identity = 75/280 (26.79%), Postives = 138/280 (49.29%), Query Frame = 1 Query: 3862 FRQKCQHIVDKKSFDYLVLFFITLNCITLAMERPSIPPHSKERL--FLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKFYYCDGPHLQAVKTKNDCLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFH 4695 F K + IVD K F ++ I +N +++ +E P E L L ++N +FT +F EM++K+L+ G L Y+++ +NI DG +V IS+ + ++G ++ +LR FRLLR L+ +R + P L+ + L+ ++ + + F IF ILG+ LF KF LK + + NFD+L A++ +F + +++ W ++Y G+ + + WA +YF++ + + + N+ V ++VE F Sbjct: 782 FSGKLRRIVDSKYFSRGIMMAILVNTLSMGVEYHEQP----EELTNALEISNIVFTSMFALEMLLKLLACGPL----GYIRNPYNIFDGIIVVISVWE-----IVGQADGGLSVLRTFRLLRVLKLVRFL---PALRRQLVVLVKTMDNVATFCTLLMLFIFIFSILGMHLFGCKF----------------SLKTDTGDTVPDRKNFDSLLWAIVTVFQILTQEDWNVVLYNGMAST----------SSWAALYFVALMTFGNYVLFNLLVAILVEGFQ 1019 HSP 5 Score: 82.0333 bits (201), Expect = 1.324e-14 Identity = 60/234 (25.64%), Postives = 117/234 (50.00%), Query Frame = 1 Query: 2101 PFNKNQNKTKRKNYLSICQQKIKTLVNDVKFQRGILIAILINTLSMGIEYHQQPVQLTQTLEFSNIVFSILFLIEMILKLIGEGILGYIKNGFNLFDGIIVVLGVIELCQQG---------GTSGLSILRTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKFCTIENNKRTCDR-KNFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTS 2772 P+ + + T+R + S+C L I I +N ++M +E++ QP L + L++ N VF+I+F+ E LKL+ G + K+ +N D IV+L ++ + + + + I+R R+ R+LKL++ +R L +++ + V L +L FI++ LG+ LFG C+ +N R F + + +T+F++ T ++WN ++ + + S Sbjct: 1592 PYYADYSPTRRSIH-SLCTSHYLDLF--------ITFIICVNVITMSMEHYNQPKSLDEALKYCNYVFTIVFVFEAALKLVAFGFRRFFKDRWNQLDLAIVLLSLMGITLEEIEMSAALPINPTIIRIMRVLRIARVLKLLKMATGMRALLDTVVQALPQVGNLGLLFMLLFFIYAALGVELFGRLECSEDNPCEGLSRHATFSNFGMAFLTLFRVSTGDNWNGIMKDTLRECS 1816 HSP 6 Score: 80.1073 bits (196), Expect = 5.719e-14 Identity = 61/173 (35.26%), Postives = 96/173 (55.49%), Query Frame = 1 Query: 3865 RQKCQHIVDKKSFDYLVLFFITLNCITLAMERP--SIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKG 4377 R C +V F+++ + I LNC+TL M RP + S+ L + F EM+IK+++ GL G + YL WN +D F+V +++ + GH+ + I R +R LRPLR I+R P ++++V LL +L +GN++L+C F IFGI+GVQL+ G Sbjct: 90 RSWCLRLVCNPWFEHVSMLVIMLNCVTLGMFRPCEDVECGSERCNILEAFDAFIFAFFAVEMVIKMVALGLF-GQKCYLGDTWNRLDFFIVVAGMMEYSLD---GHNVSLSAI----RTVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAG 254 HSP 7 Score: 72.7886 bits (177), Expect = 8.866e-12 Identity = 71/224 (31.70%), Postives = 117/224 (52.23%), Query Frame = 1 Query: 4798 WENYS-KWRRTINSVVTSKYFDLAIAGVIGLNVITMATEFHMMPQVLKTALKVFNYFFTSTFVXXXXXXXXXXXXXRYISDKWNQLDMMIVILSIAGVVIDEVESNFMPINPTIMRVMRVLRIARVLKLLKMASGIRALLDTVIQALPQVGNXXXXXXXXXXXXXXXXVELFG-----RLECSDINPCVGLGRHAHFENFGMAFLTLFRIATGDNWNGIMKDTL 5451 W +S K RR +V SKYF I I +N ++M E+H P+ L AL++ N FTS F LE LLKL+A G YI + +N D +IV++S+ +V + + + V+R R+ RVLKL++ +R L +++ + V L L +IF+ LG+ LFG + + D P +F++ A +T+F+I T ++WN ++ + + Sbjct: 779 WVTFSGKLRR----IVDSKYFSRGIMMAILVNTLSMGVEYHEQPEELTNALEISNIVFTSMFALEMLLKLLACGPLGYIRNPYNIFDGIIVVISVWEIV-GQADGG--------LSVLRTFRLLRVLKLVRFLPALRRQLVVLVKTMDNVATFCTLLMLFIFIFSILGMHLFGCKFSLKTDTGDTVP-----DRKNFDSLLWAIVTVFQILTQEDWNVVLYNGM 984 HSP 8 Score: 68.5514 bits (166), Expect = 1.922e-10 Identity = 61/282 (21.63%), Postives = 131/282 (46.45%), Query Frame = 1 Query: 2134 KNYLSICQQKIKTLVNDVKFQRGILIAILINTLSMGIEYHQQPVQLTQT--LEFSNIVFSILFLIEMILKLIGEGIL----GYIKNGFNLFDGIIVVLGVIELCQQGGTSGLSILRTFRLLRILKL-------VRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKFCTIEN-------NKRTCD---------RKNFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTS----------SWAALYFIALMTFGNYVLFNLLVAILVEGF 2862 +N + QK+ + F +L+ I +N +++ +E T+ L SN +F+ +F+ EM++K++ G+L Y+++ +NL DG++V++ ++++ ++G + + + L + P L+ + +I ++ + + F IF ILG+ LF KF E K C + NFD+L +++++F + +++ W ++Y+G+ W LYFI+ + ++ + N+ V ++VE F Sbjct: 1280 QNRFRVSCQKV---ITHKMFDHVVLVFIFLNCVTIALERPDIDPGSTERVFLSVSNYIFTAIFVAEMMVKVVALGLLSGEHAYLQSSWNLLDGLLVLVSLVDIVVAMASAGGAKILGVLRVLRLLRTLRPLRVISRAPGLKLVVETLISSLRPIGNIVLICCAFFIIFGILGVQLFKGKFYYCEGPDTRNISTKAQCRAAHYRWVRRKYNFDNLGQALMSLFVLSSKDGWVNIMYDGLDAVGVDQQPVQNHNPWMLLYFISFLLIVSFFVLNMFVGVVVENF 1558 HSP 9 Score: 65.4698 bits (158), Expect = 1.612e-9 Identity = 44/172 (25.58%), Postives = 81/172 (47.09%), Query Frame = 1 Query: 178 PQDNRSRRETLIGNKSDFNL-TDKSKADHCQQETDGTP---------INPNESLIYHGFYATVFHIFHQNKHPRDWCLKIITWPWFEQLSMTIIAVNCITLSMYQPCGDQNCETSKCQIMQAFDYIIFAFFTCEMVIKIIAMGFL-GDLGYFGDTWNRLDMFIVIVGSIEIL 660 P R R ++ SDF L D + D + + D + P + A ++F R C K+IT F+ + + I +NC+T+++ +P D + +++ + +YI A F EM++K++A+G L G+ Y +WN LD +V+V ++I+ Sbjct: 1211 PTKCRDRDGQVVALPSDFFLRIDSHREDAAELDDDSEDSCCLRLHKVLEPYKPQWCRSREAWALYLFSPQNRFRVSCQKVITHKMFDHVVLVFIFLNCVTIALERP--DIDPGSTERVFLSVSNYIFTAIFVAEMMVKVVALGLLSGEHAYLQSSWNLLDGLLVLVSLVDIV 1380 HSP 10 Score: 56.225 bits (134), Expect = 9.572e-7 Identity = 32/115 (27.83%), Postives = 60/115 (52.17%), Query Frame = 1 Query: 4399 PHLQAV-KTKNDCLKYSQ---------NEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFHKCQENQ 4713 P + V +N C+ ++Q + N NFDN+G A +A+F + + +GWV IMY +DA H+ + IYFI +++ +FF++N+ + V+ F + ++ + Sbjct: 325 PQAEGVGAARNACINWNQYYNVCRSGDSNPHNGAINFDNIGYAWIAIFQVITLEGWVDIMYYVMDA----------HSFYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQRE 429 HSP 11 Score: 54.6842 bits (130), Expect = 2.902e-6 Identity = 26/80 (32.50%), Postives = 48/80 (60.00%), Query Frame = 1 Query: 1195 NFDNIGFAWVAIFQVISMESWVDIMYYVQDA----------HSFWDWIYFVALIIIGSFFMINLCLVVIASQFSETKRRE 1404 NFDN+G A +++F + S + WV+IMY DA H+ W +YF++ ++I SFF++N+ + V+ F + ++ + Sbjct: 1486 NFDNLGQALMSLFVLSSKDGWVNIMYDGLDAVGVDQQPVQNHNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHKCRQHQ 1565 HSP 12 Score: 53.5286 bits (127), Expect = 5.829e-6 Identity = 35/132 (26.52%), Postives = 71/132 (53.79%), Query Frame = 1 Query: 2173 LVNDVKFQRGILIAILINTLSMGIEYHQQPVQLTQT----LEFSNIVFSILFLIEMILKLIGEGILG---YIKNGFNLFDGIIVVLGVIELCQQGGTSGLSILRTFRLLRILKLVRFMPALRQQLFVMIRTI 2547 LV + F+ ++ I++N +++G+ + V+ LE + F +EM++K++ G+ G Y+ + +N D IVV G++E G LS +RT R+LR L+ + +P++R + +++ T+ Sbjct: 96 LVCNPWFEHVSMLVIMLNCVTLGMFRPCEDVECGSERCNILEAFDAFIFAFFAVEMVIKMVALGLFGQKCYLGDTWNRLDFFIVVAGMMEYSLDGHNVSLSAIRTVRVLRPLRAINRVPSMRILVTLLLDTL 227
BLAST of Voltage-dependent T-type calcium channel subunit alpha vs. Ensembl Human
Match: CACNA1H (calcium voltage-gated channel subunit alpha1 H [Source:HGNC Symbol;Acc:HGNC:1395]) HSP 1 Score: 658.292 bits (1697), Expect = 0.000e+0 Identity = 411/676 (60.80%), Postives = 507/676 (75.00%), Query Frame = 1 Query: 3667 REKALEEPDDSNSESQNSSRMNNVEDPDEEDMEAMICLSKCCPQPKGIFAKRYYHSLYVFSVDNQFRQKCQHIVDKKSFDYLVLFFITLNCITLAMERPSIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKFYYCDGPHLQAVKTKNDCLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFHKCQENQXXXXXXXXXXXXXXXXXXXXXHLRAPLYWENYSKWRRTINSVVTSKYFDLAIAGVIGLNVITMATEFHMMPQVLKTALKVFNYFFTSTFVXXXXXXXXXXXXXRYISDKWNQLDMMIVILSIAGVVIDEVE-SNFMPINPTIMRVMRVLRIARVLKLLKMASGIRALLDTVIQALPQVGNXXXXXXXXXXXXXXXXVELFGRLECSDINPCVGLGRHAHFENFGMAFLTLFRIATGDNWNGIMKDTLREKCISSEDCQRNCCVSAIIA--PIYFVIFXXXXXXXXXXXXXXXXXKHLEESHKMMCDDYELEREVQRDLDEEAKELAR 5685 RE A E DDS E R++ V +P + C S R +LY+FS N+FR CQ ++ K FD++VL FI LNC+T+A+ERP I P S ER+FL+V+NYIFT IF EM++KV++ GLL G+ AYL+S WN++DG LV +SL+D+ + + +I G+LRV RLLRTLRPLRVISRAPGLKLVV+TL+SSLRPIGNIVLICC FFIIFGILGVQLFKGKFYYC+GP + + TK C + + W +KYNFDNLGQALM+LFVLSSKDGWV IMY G+DAVGV+ QP +NHN W L+YFISFLL+V+FFVLNMFVGVVVENFHKC+++QE EE RR KR RRLE++R+ + Y+ +YS RR+I+S+ TS Y DL I +I +NVITM+ E + P+ L ALK NY FT FV EA LKLVA G R+ D+WNQLD+ IV+LS+ G+ ++E+E S +PINPTI+R+MRVLRIARVLKLLKMA+G+RALLDTV+QALPQVGNLGLLF LLF+I+AALGVELFGRLECS+ NPC GL RHA F NFGMAFLTLFR++TGDNWNGIMKDTLRE S ED C+S + A P+YFV FVL+AQFVLVNVVVAVLMKHLEES+K +D EL+ E++ ++ + R Sbjct: 1236 REDAAELDDDS--EDSCCLRLHKVLEP----YKPQWCRS------------REAWALYLFSPQNRFRVSCQKVITHKMFDHVVLVFIFLNCVTIALERPDIDPGSTERVFLSVSNYIFTAIFVAEMMVKVVALGLLSGEHAYLQSSWNLLDGLLVLVSLVDIVVAMASAGGAKILGVLRVLRLLRTLRPLRVISRAPGLKLVVETLISSLRPIGNIVLICCAFFIIFGILGVQLFKGKFYYCEGPDTRNISTKAQC-RAAHYRWVRRKYNFDNLGQALMSLFVLSSKDGWVNIMYDGLDAVGVDQQPVQNHNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHKCRQHQEAEEARRREEKRLRRLERRRRKAQRRPYYADYSPTRRSIHSLCTSHYLDLFITFIICVNVITMSMEHYNQPKSLDEALKYCNYVFTIVFVFEAALKLVAFGFRRFFKDRWNQLDLAIVLLSLMGITLEEIEMSAALPINPTIIRIMRVLRIARVLKLLKMATGMRALLDTVVQALPQVGNLGLLFMLLFFIYAALGVELFGRLECSEDNPCEGLSRHATFSNFGMAFLTLFRVSTGDNWNGIMKDTLRE--CSREDKH---CLSYLPALSPVYFVTFVLVAQFVLVNVVVAVLMKHLEESNKEAREDAELDAEIELEMAQGPGSARR 1887 HSP 2 Score: 372.474 bits (955), Expect = 2.988e-103 Identity = 237/451 (52.55%), Postives = 306/451 (67.85%), Query Frame = 1 Query: 313 YHGFYATVFHIFHQNKHPRDWCLKIITWPWFEQLSMTIIAVNCITLSMYQPCGDQNCETSKCQIMQAFDYIIFAFFTCEMVIKIIAMGFLGDLGYFGDTWNRLDMFIVIVGSIEILPSTGNNIGLTAIRTIRVLRPLRAINRIPSMRIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQMWQGVLRNRCYL------NLNESFRHPGLNLSSFYQINRTLFLNAVDKDFICSTDKNNGILKCSDIPPSIMLLSNNSL--QICKQPARPFTDNLPTKHSCVNWNQYYTDCQPGEKNPYEGAINFDNIGFAWVAIFQVISMESWVDIMYYVQDAHSFWDWIYFVALIIIGSFFMINLCLVVIASQFSETKRRETERMWIERRRFNSSNCSSISKDEPQTCYLEXXXXXXXXXXXXYRRIVKLYNQIQIRHSK-----TAQGNYQNKLKRQRK 1626 Y ATVF Q PR WCL+++ PWFE +SM +I +NC+TL M++PC D C + +C I++AFD IFAFF EMVIK++A+G G Y GDTWNRLD FIV+ G +E G+N+ L+AIRT+RVLRPLRAINR+PSMRILV LLLDTLPMLGNVLLLCFFVFFIFGI+GVQ+W G+LRNRC+L N N +F P +YQ + FICS+ ++NG+ KCS IP L +L + QP +++C+NWNQYY C+ G+ NP+ GAINFDNIG+AW+AIFQVI++E WVDIMYYV DAHSF+++IYF+ LII+GSFFMINLCLVVIA+QFSETK+RE++ M +R R S++ + S EP +CY E++K + I K+ RR ++LY + Q R K QG Q RQR+ Sbjct: 72 YPALAATVFFCLGQTTRPRSWCLRLVCNPWFEHVSMLVIMLNCVTLGMFRPCEDVECGSERCNILEAFDAFIFAFFAVEMVIKMVALGLFGQKCYLGDTWNRLDFFIVVAGMMEYS-LDGHNVSLSAIRTVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAGLLRNRCFLDSAFVRNNNLTFLRP------YYQTE-----EGEENPFICSSRRDNGMQKCSHIPGRRELRMPCTLGWEAYTQPQAEGVGA--ARNACINWNQYYNVCRSGDSNPHNGAINFDNIGYAWIAIFQVITLEGWVDIMYYVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQRESQLMREQRARHLSNDSTLASFSEPGSCYEELLKYVGHIFRKVKRRSLRLYARWQSRWRKKVDPSAVQG--QGPGHRQRR 506 HSP 3 Score: 337.806 bits (865), Expect = 1.792e-92 Identity = 189/320 (59.06%), Postives = 237/320 (74.06%), Query Frame = 1 Query: 2161 KIKTLVNDVKFQRGILIAILINTLSMGIEYHQQPVQLTQTLEFSNIVFSILFLIEMILKLIGEGILGYIKNGFNLFDGIIVVLGVIELCQQGGTSGLSILRTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKFCTIENNKRTC-DRKNFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTSSWAALYFIALMTFGNYVLFNLLVAILVEGFSSER------LDEQKLLHNYRQSLKKRRANNKQLRIMQHQSENLVLLTNSIQKDQTGENQKISSQPPVIIHTAATPMPTPRSSPY 3099 K++ +V+ F RGI++AIL+NTLSMG+EYH+QP +LT LE SNIVF+ +F +EM+LKL+ G LGYI+N +N+FDGIIVV+ V E+ Q GLS+LRTFRLLR+LKLVRF+PALR+QL V+++T+DNVATF LL+LFIFIFSILGM LFGCKF + T DRKNFDSLLW+IVTVFQILTQEDWN VLYNGM TSSWAALYF+ALMTFGNYVLFNLLVAILVEGF +E DE K ++ + K R + Q+ L + + ++ + E + S PP+I+ TAATPMPTP+SSP+ Sbjct: 785 KLRRIVDSKYFSRGIMMAILVNTLSMGVEYHEQPEELTNALEISNIVFTSMFALEMLLKLLACGPLGYIRNPYNIFDGIIVVISVWEIVGQA-DGGLSVLRTFRLLRVLKLVRFLPALRRQLVVLVKTMDNVATFCTLLMLFIFIFSILGMHLFGCKFSLKTDTGDTVPDRKNFDSLLWAIVTVFQILTQEDWNVVLYNGMASTSSWAALYFVALMTFGNYVLFNLLVAILVEGFQAEGDANRSDTDEDKTSVHFEEDFHKLR---------ELQTTELKMCSLAVTPNGHLEGRG-SLSPPLIMCTAATPMPTPKSSPF 1093 HSP 4 Score: 112.464 bits (280), Expect = 9.012e-24 Identity = 75/280 (26.79%), Postives = 138/280 (49.29%), Query Frame = 1 Query: 3862 FRQKCQHIVDKKSFDYLVLFFITLNCITLAMERPSIPPHSKERL--FLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKFYYCDGPHLQAVKTKNDCLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFH 4695 F K + IVD K F ++ I +N +++ +E P E L L ++N +FT +F EM++K+L+ G L Y+++ +NI DG +V IS+ + ++G ++ +LR FRLLR L+ +R + P L+ + L+ ++ + + F IF ILG+ LF KF LK + + NFD+L A++ +F + +++ W ++Y G+ + + WA +YF++ + + + N+ V ++VE F Sbjct: 782 FSGKLRRIVDSKYFSRGIMMAILVNTLSMGVEYHEQP----EELTNALEISNIVFTSMFALEMLLKLLACGPL----GYIRNPYNIFDGIIVVISVWE-----IVGQADGGLSVLRTFRLLRVLKLVRFL---PALRRQLVVLVKTMDNVATFCTLLMLFIFIFSILGMHLFGCKF----------------SLKTDTGDTVPDRKNFDSLLWAIVTVFQILTQEDWNVVLYNGMAST----------SSWAALYFVALMTFGNYVLFNLLVAILVEGFQ 1019 HSP 5 Score: 82.0333 bits (201), Expect = 1.324e-14 Identity = 60/234 (25.64%), Postives = 117/234 (50.00%), Query Frame = 1 Query: 2101 PFNKNQNKTKRKNYLSICQQKIKTLVNDVKFQRGILIAILINTLSMGIEYHQQPVQLTQTLEFSNIVFSILFLIEMILKLIGEGILGYIKNGFNLFDGIIVVLGVIELCQQG---------GTSGLSILRTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKFCTIENNKRTCDR-KNFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTS 2772 P+ + + T+R + S+C L I I +N ++M +E++ QP L + L++ N VF+I+F+ E LKL+ G + K+ +N D IV+L ++ + + + + I+R R+ R+LKL++ +R L +++ + V L +L FI++ LG+ LFG C+ +N R F + + +T+F++ T ++WN ++ + + S Sbjct: 1592 PYYADYSPTRRSIH-SLCTSHYLDLF--------ITFIICVNVITMSMEHYNQPKSLDEALKYCNYVFTIVFVFEAALKLVAFGFRRFFKDRWNQLDLAIVLLSLMGITLEEIEMSAALPINPTIIRIMRVLRIARVLKLLKMATGMRALLDTVVQALPQVGNLGLLFMLLFFIYAALGVELFGRLECSEDNPCEGLSRHATFSNFGMAFLTLFRVSTGDNWNGIMKDTLRECS 1816 HSP 6 Score: 80.1073 bits (196), Expect = 5.719e-14 Identity = 61/173 (35.26%), Postives = 96/173 (55.49%), Query Frame = 1 Query: 3865 RQKCQHIVDKKSFDYLVLFFITLNCITLAMERP--SIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKG 4377 R C +V F+++ + I LNC+TL M RP + S+ L + F EM+IK+++ GL G + YL WN +D F+V +++ + GH+ + I R +R LRPLR I+R P ++++V LL +L +GN++L+C F IFGI+GVQL+ G Sbjct: 90 RSWCLRLVCNPWFEHVSMLVIMLNCVTLGMFRPCEDVECGSERCNILEAFDAFIFAFFAVEMVIKMVALGLF-GQKCYLGDTWNRLDFFIVVAGMMEYSLD---GHNVSLSAI----RTVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAG 254 HSP 7 Score: 72.7886 bits (177), Expect = 8.866e-12 Identity = 71/224 (31.70%), Postives = 117/224 (52.23%), Query Frame = 1 Query: 4798 WENYS-KWRRTINSVVTSKYFDLAIAGVIGLNVITMATEFHMMPQVLKTALKVFNYFFTSTFVXXXXXXXXXXXXXRYISDKWNQLDMMIVILSIAGVVIDEVESNFMPINPTIMRVMRVLRIARVLKLLKMASGIRALLDTVIQALPQVGNXXXXXXXXXXXXXXXXVELFG-----RLECSDINPCVGLGRHAHFENFGMAFLTLFRIATGDNWNGIMKDTL 5451 W +S K RR +V SKYF I I +N ++M E+H P+ L AL++ N FTS F LE LLKL+A G YI + +N D +IV++S+ +V + + + V+R R+ RVLKL++ +R L +++ + V L L +IF+ LG+ LFG + + D P +F++ A +T+F+I T ++WN ++ + + Sbjct: 779 WVTFSGKLRR----IVDSKYFSRGIMMAILVNTLSMGVEYHEQPEELTNALEISNIVFTSMFALEMLLKLLACGPLGYIRNPYNIFDGIIVVISVWEIV-GQADGG--------LSVLRTFRLLRVLKLVRFLPALRRQLVVLVKTMDNVATFCTLLMLFIFIFSILGMHLFGCKFSLKTDTGDTVP-----DRKNFDSLLWAIVTVFQILTQEDWNVVLYNGM 984 HSP 8 Score: 68.5514 bits (166), Expect = 1.922e-10 Identity = 61/282 (21.63%), Postives = 131/282 (46.45%), Query Frame = 1 Query: 2134 KNYLSICQQKIKTLVNDVKFQRGILIAILINTLSMGIEYHQQPVQLTQT--LEFSNIVFSILFLIEMILKLIGEGIL----GYIKNGFNLFDGIIVVLGVIELCQQGGTSGLSILRTFRLLRILKL-------VRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKFCTIEN-------NKRTCD---------RKNFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTS----------SWAALYFIALMTFGNYVLFNLLVAILVEGF 2862 +N + QK+ + F +L+ I +N +++ +E T+ L SN +F+ +F+ EM++K++ G+L Y+++ +NL DG++V++ ++++ ++G + + + L + P L+ + +I ++ + + F IF ILG+ LF KF E K C + NFD+L +++++F + +++ W ++Y+G+ W LYFI+ + ++ + N+ V ++VE F Sbjct: 1280 QNRFRVSCQKV---ITHKMFDHVVLVFIFLNCVTIALERPDIDPGSTERVFLSVSNYIFTAIFVAEMMVKVVALGLLSGEHAYLQSSWNLLDGLLVLVSLVDIVVAMASAGGAKILGVLRVLRLLRTLRPLRVISRAPGLKLVVETLISSLRPIGNIVLICCAFFIIFGILGVQLFKGKFYYCEGPDTRNISTKAQCRAAHYRWVRRKYNFDNLGQALMSLFVLSSKDGWVNIMYDGLDAVGVDQQPVQNHNPWMLLYFISFLLIVSFFVLNMFVGVVVENF 1558 HSP 9 Score: 65.4698 bits (158), Expect = 1.612e-9 Identity = 44/172 (25.58%), Postives = 81/172 (47.09%), Query Frame = 1 Query: 178 PQDNRSRRETLIGNKSDFNL-TDKSKADHCQQETDGTP---------INPNESLIYHGFYATVFHIFHQNKHPRDWCLKIITWPWFEQLSMTIIAVNCITLSMYQPCGDQNCETSKCQIMQAFDYIIFAFFTCEMVIKIIAMGFL-GDLGYFGDTWNRLDMFIVIVGSIEIL 660 P R R ++ SDF L D + D + + D + P + A ++F R C K+IT F+ + + I +NC+T+++ +P D + +++ + +YI A F EM++K++A+G L G+ Y +WN LD +V+V ++I+ Sbjct: 1211 PTKCRDRDGQVVALPSDFFLRIDSHREDAAELDDDSEDSCCLRLHKVLEPYKPQWCRSREAWALYLFSPQNRFRVSCQKVITHKMFDHVVLVFIFLNCVTIALERP--DIDPGSTERVFLSVSNYIFTAIFVAEMMVKVVALGLLSGEHAYLQSSWNLLDGLLVLVSLVDIV 1380 HSP 10 Score: 56.225 bits (134), Expect = 9.572e-7 Identity = 32/115 (27.83%), Postives = 60/115 (52.17%), Query Frame = 1 Query: 4399 PHLQAV-KTKNDCLKYSQ---------NEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFHKCQENQ 4713 P + V +N C+ ++Q + N NFDN+G A +A+F + + +GWV IMY +DA H+ + IYFI +++ +FF++N+ + V+ F + ++ + Sbjct: 325 PQAEGVGAARNACINWNQYYNVCRSGDSNPHNGAINFDNIGYAWIAIFQVITLEGWVDIMYYVMDA----------HSFYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQRE 429 HSP 11 Score: 54.6842 bits (130), Expect = 2.902e-6 Identity = 26/80 (32.50%), Postives = 48/80 (60.00%), Query Frame = 1 Query: 1195 NFDNIGFAWVAIFQVISMESWVDIMYYVQDA----------HSFWDWIYFVALIIIGSFFMINLCLVVIASQFSETKRRE 1404 NFDN+G A +++F + S + WV+IMY DA H+ W +YF++ ++I SFF++N+ + V+ F + ++ + Sbjct: 1486 NFDNLGQALMSLFVLSSKDGWVNIMYDGLDAVGVDQQPVQNHNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHKCRQHQ 1565 HSP 12 Score: 53.5286 bits (127), Expect = 5.829e-6 Identity = 35/132 (26.52%), Postives = 71/132 (53.79%), Query Frame = 1 Query: 2173 LVNDVKFQRGILIAILINTLSMGIEYHQQPVQLTQT----LEFSNIVFSILFLIEMILKLIGEGILG---YIKNGFNLFDGIIVVLGVIELCQQGGTSGLSILRTFRLLRILKLVRFMPALRQQLFVMIRTI 2547 LV + F+ ++ I++N +++G+ + V+ LE + F +EM++K++ G+ G Y+ + +N D IVV G++E G LS +RT R+LR L+ + +P++R + +++ T+ Sbjct: 96 LVCNPWFEHVSMLVIMLNCVTLGMFRPCEDVECGSERCNILEAFDAFIFAFFAVEMVIKMVALGLFGQKCYLGDTWNRLDFFIVVAGMMEYSLDGHNVSLSAIRTVRVLRPLRAINRVPSMRILVTLLLDTL 227
BLAST of Voltage-dependent T-type calcium channel subunit alpha vs. Ensembl Human
Match: CACNA1H (calcium voltage-gated channel subunit alpha1 H [Source:HGNC Symbol;Acc:HGNC:1395]) HSP 1 Score: 657.907 bits (1696), Expect = 0.000e+0 Identity = 398/629 (63.28%), Postives = 490/629 (77.90%), Query Frame = 1 Query: 3820 RYYHSLYVFSVDNQFRQKCQHIVDKKSFDYLVLFFITLNCITLAMERPSIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKFYYCDGPHLQAVKTKNDCLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFHKCQENQXXXXXXXXXXXXXXXXXXXXXHLRAPL-----------YWENYSKWRRTINSVVTSKYFDLAIAGVIGLNVITMATEFHMMPQVLKTALKVFNYFFTSTFVXXXXXXXXXXXXXRYISDKWNQLDMMIVILSIAGVVIDEVE-SNFMPINPTIMRVMRVLRIARVLKLLKMASGIRALLDTVIQALPQVGNXXXXXXXXXXXXXXXXVELFGRLECSDINPCVGLGRHAHFENFGMAFLTLFRIATGDNWNGIMKDTLREKCISSEDCQRNCCVSAIIA--PIYFVIFXXXXXXXXXXXXXXXXXKHLEESHKMMCDDYELEREVQRDLDE 5664 R +LY+FS N+FR CQ ++ K FD++VL FI LNC+T+A+ERP I P S ER+FL+V+NYIFT IF EM++KV++ GLL G+ AYL+S WN++DG LV +SL+D+ + + +I G+LRV RLLRTLRPLRVISRAPGLKLVV+TL+SSLRPIGNIVLICC FFIIFGILGVQLFKGKFYYC+GP + + TK C + + W +KYNFDNLGQALM+LFVLSSKDGWV IMY G+DAVGV+ QP +NHN W L+YFISFLL+V+FFVLNMFVGVVVENFHKC+++QE EE RR KR RRLE++R+ P+ Y+ +YS RR+I+S+ TS Y DL I +I +NVITM+ E + P+ L ALK NY FT FV EA LKLVA G R+ D+WNQLD+ IV+LS+ G+ ++E+E S +PINPTI+R+MRVLRIARVLKLLKMA+G+RALLDTV+QALPQVGNLGLLF LLF+I+AALGVELFGRLECS+ NPC GL RHA F NFGMAFLTLFR++TGDNWNGIMKDTLRE S ED C+S + A P+YFV FVL+AQFVLVNVVVAVLMKHLEES+K +D EL+ E++ ++ + Sbjct: 11 REAWALYLFSPQNRFRVSCQKVITHKMFDHVVLVFIFLNCVTIALERPDIDPGSTERVFLSVSNYIFTAIFVAEMMVKVVALGLLSGEHAYLQSSWNLLDGLLVLVSLVDIVVAMASAGGAKILGVLRVLRLLRTLRPLRVISRAPGLKLVVETLISSLRPIGNIVLICCAFFIIFGILGVQLFKGKFYYCEGPDTRNISTKAQC-RAAHYRWVRRKYNFDNLGQALMSLFVLSSKDGWVNIMYDGLDAVGVDQQPVQNHNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHKCRQHQEAEEARRREEKRLRRLERRRRSKALPVAVAVAEAQRRPYYADYSPTRRSIHSLCTSHYLDLFITFIICVNVITMSMEHYNQPKSLDEALKYCNYVFTIVFVFEAALKLVAFGFRRFFKDRWNQLDLAIVLLSLMGITLEEIEMSAALPINPTIIRIMRVLRIARVLKLLKMATGMRALLDTVVQALPQVGNLGLLFMLLFFIYAALGVELFGRLECSEDNPCEGLSRHATFSNFGMAFLTLFRVSTGDNWNGIMKDTLRE--CSREDKH---CLSYLPALSPVYFVTFVLVAQFVLVNVVVAVLMKHLEESNKEAREDAELDAEIELEMAQ 633 HSP 2 Score: 87.4261 bits (215), Expect = 2.722e-16 Identity = 62/237 (26.16%), Postives = 119/237 (50.21%), Query Frame = 1 Query: 2092 HRRPFNKNQNKTKRKNYLSICQQKIKTLVNDVKFQRGILIAILINTLSMGIEYHQQPVQLTQTLEFSNIVFSILFLIEMILKLIGEGILGYIKNGFNLFDGIIVVLGVIELCQQG---------GTSGLSILRTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKFCTIENNKRTCDR-KNFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTS 2772 RRP+ + + T+R + S+C L I I +N ++M +E++ QP L + L++ N VF+I+F+ E LKL+ G + K+ +N D IV+L ++ + + + + I+R R+ R+LKL++ +R L +++ + V L +L FI++ LG+ LFG C+ +N R F + + +T+F++ T ++WN ++ + + S Sbjct: 342 QRRPYYADYSPTRRSIH-SLCTSHYLDLF--------ITFIICVNVITMSMEHYNQPKSLDEALKYCNYVFTIVFVFEAALKLVAFGFRRFFKDRWNQLDLAIVLLSLMGITLEEIEMSAALPINPTIIRIMRVLRIARVLKLLKMATGMRALLDTVVQALPQVGNLGLLFMLLFFIYAALGVELFGRLECSEDNPCEGLSRHATFSNFGMAFLTLFRVSTGDNWNGIMKDTLRECS 569 HSP 3 Score: 69.3218 bits (168), Expect = 9.685e-11 Identity = 61/282 (21.63%), Postives = 132/282 (46.81%), Query Frame = 1 Query: 2134 KNYLSICQQKIKTLVNDVKFQRGILIAILINTLSMGIEYHQQPVQLTQT--LEFSNIVFSILFLIEMILKLIGEGIL----GYIKNGFNLFDGIIVVLGVIELCQQGGTSGLSILRTFRLLRILKL-------VRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKFCTIE-------NNKRTCD---------RKNFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTS----------SWAALYFIALMTFGNYVLFNLLVAILVEGF 2862 +N + QK+ + F +L+ I +N +++ +E T+ L SN +F+ +F+ EM++K++ G+L Y+++ +NL DG++V++ ++++ ++G + + + L + P L+ + +I ++ + + F IF ILG+ LF KF E + K C + NFD+L +++++F + +++ W ++Y+G+ W LYFI+ + ++ + N+ V ++VE F Sbjct: 22 QNRFRVSCQKV---ITHKMFDHVVLVFIFLNCVTIALERPDIDPGSTERVFLSVSNYIFTAIFVAEMMVKVVALGLLSGEHAYLQSSWNLLDGLLVLVSLVDIVVAMASAGGAKILGVLRVLRLLRTLRPLRVISRAPGLKLVVETLISSLRPIGNIVLICCAFFIIFGILGVQLFKGKFYYCEGPDTRNISTKAQCRAAHYRWVRRKYNFDNLGQALMSLFVLSSKDGWVNIMYDGLDAVGVDQQPVQNHNPWMLLYFISFLLIVSFFVLNMFVGVVVENF 300 HSP 4 Score: 65.0846 bits (157), Expect = 1.470e-9 Identity = 33/112 (29.46%), Postives = 63/112 (56.25%), Query Frame = 1 Query: 328 ATVFHIFHQNKHPRDWCLKIITWPWFEQLSMTIIAVNCITLSMYQPCGDQNCETSKCQIMQAFDYIIFAFFTCEMVIKIIAMGFL-GDLGYFGDTWNRLDMFIVIVGSIEIL 660 A ++F R C K+IT F+ + + I +NC+T+++ +P D + +++ + +YI A F EM++K++A+G L G+ Y +WN LD +V+V ++I+ Sbjct: 13 AWALYLFSPQNRFRVSCQKVITHKMFDHVVLVFIFLNCVTIALERP--DIDPGSTERVFLSVSNYIFTAIFVAEMMVKVVALGLLSGEHAYLQSSWNLLDGLLVLVSLVDIV 122 HSP 5 Score: 54.6842 bits (130), Expect = 2.223e-6 Identity = 26/80 (32.50%), Postives = 48/80 (60.00%), Query Frame = 1 Query: 1195 NFDNIGFAWVAIFQVISMESWVDIMYYVQDA----------HSFWDWIYFVALIIIGSFFMINLCLVVIASQFSETKRRE 1404 NFDN+G A +++F + S + WV+IMY DA H+ W +YF++ ++I SFF++N+ + V+ F + ++ + Sbjct: 228 NFDNLGQALMSLFVLSSKDGWVNIMYDGLDAVGVDQQPVQNHNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHKCRQHQ 307
BLAST of Voltage-dependent T-type calcium channel subunit alpha vs. Ensembl Human
Match: CACNA1H (calcium voltage-gated channel subunit alpha1 H [Source:HGNC Symbol;Acc:HGNC:1395]) HSP 1 Score: 657.522 bits (1695), Expect = 0.000e+0 Identity = 399/625 (63.84%), Postives = 490/625 (78.40%), Query Frame = 1 Query: 3820 RYYHSLYVFSVDNQFRQKCQHIVDKKSFDYLVLFFITLNCITLAMERPSIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKFYYCDGPHLQAVKTKNDCLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFHKCQENQXXXXXXXXXXXXXXXXXXXXXHL-------RAPLYWENYSKWRRTINSVVTSKYFDLAIAGVIGLNVITMATEFHMMPQVLKTALKVFNYFFTSTFVXXXXXXXXXXXXXRYISDKWNQLDMMIVILSIAGVVIDEVE-SNFMPINPTIMRVMRVLRIARVLKLLKMASGIRALLDTVIQALPQVGNXXXXXXXXXXXXXXXXVELFGRLECSDINPCVGLGRHAHFENFGMAFLTLFRIATGDNWNGIMKDTLREKCISSEDCQRNCCVSAIIA--PIYFVIFXXXXXXXXXXXXXXXXXKHLEESHKMMCDDYELEREVQRDLDE 5664 R +LY+FS N+FR CQ ++ K FD++VL FI LNC+T+A+ERP I P S ER+FL+V+NYIFT IF EM++KV++ GLL G+ AYL+S WN++DG LV +SL+D+ + + +I G+LRV RLLRTLRPLRVISRAPGLKLVV+TL+SSLRPIGNIVLICC FFIIFGILGVQLFKGKFYYC+GP + + TK C + + W +KYNFDNLGQALM+LFVLSSKDGWV IMY G+DAVGV+ QP +NHN W L+YFISFLL+V+FFVLNMFVGVVVENFHKC+++QE EE RR KR RRLE++R+ R P Y+ +YS RR+I+S+ TS Y DL I +I +NVITM+ E + P+ L ALK NY FT FV EA LKLVA G R+ D+WNQLD+ IV+LS+ G+ ++E+E S +PINPTI+R+MRVLRIARVLKLLKMA+G+RALLDTV+QALPQVGNLGLLF LLF+I+AALGVELFGRLECS+ NPC GL RHA F NFGMAFLTLFR++TGDNWNGIMKDTLRE S ED C+S + A P+YFV FVL+AQFVLVNVVVAVLMKHLEES+K +D EL+ E++ ++ + Sbjct: 11 REAWALYLFSPQNRFRVSCQKVITHKMFDHVVLVFIFLNCVTIALERPDIDPGSTERVFLSVSNYIFTAIFVAEMMVKVVALGLLSGEHAYLQSSWNLLDGLLVLVSLVDIVVAMASAGGAKILGVLRVLRLLRTLRPLRVISRAPGLKLVVETLISSLRPIGNIVLICCAFFIIFGILGVQLFKGKFYYCEGPDTRNISTKAQC-RAAHYRWVRRKYNFDNLGQALMSLFVLSSKDGWVNIMYDGLDAVGVDQQPVQNHNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHKCRQHQEAEEARRREEKRLRRLERRRRSTFPSPEAQRRP-YYADYSPTRRSIHSLCTSHYLDLFITFIICVNVITMSMEHYNQPKSLDEALKYCNYVFTIVFVFEAALKLVAFGFRRFFKDRWNQLDLAIVLLSLMGITLEEIEMSAALPINPTIIRIMRVLRIARVLKLLKMATGMRALLDTVVQALPQVGNLGLLFMLLFFIYAALGVELFGRLECSEDNPCEGLSRHATFSNFGMAFLTLFRVSTGDNWNGIMKDTLRE--CSREDKH---CLSYLPALSPVYFVTFVLVAQFVLVNVVVAVLMKHLEESNKEAREDAELDAEIELEMAQ 628 HSP 2 Score: 87.8113 bits (216), Expect = 1.926e-16 Identity = 63/241 (26.14%), Postives = 120/241 (49.79%), Query Frame = 1 Query: 2080 SYSKHRRPFNKNQNKTKRKNYLSICQQKIKTLVNDVKFQRGILIAILINTLSMGIEYHQQPVQLTQTLEFSNIVFSILFLIEMILKLIGEGILGYIKNGFNLFDGIIVVLGVIELCQQG---------GTSGLSILRTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKFCTIENNKRTCDR-KNFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTS 2772 S RRP+ + + T+R + S+C L I I +N ++M +E++ QP L + L++ N VF+I+F+ E LKL+ G + K+ +N D IV+L ++ + + + + I+R R+ R+LKL++ +R L +++ + V L +L FI++ LG+ LFG C+ +N R F + + +T+F++ T ++WN ++ + + S Sbjct: 333 SPEAQRRPYYADYSPTRRSIH-SLCTSHYLDLF--------ITFIICVNVITMSMEHYNQPKSLDEALKYCNYVFTIVFVFEAALKLVAFGFRRFFKDRWNQLDLAIVLLSLMGITLEEIEMSAALPINPTIIRIMRVLRIARVLKLLKMATGMRALLDTVVQALPQVGNLGLLFMLLFFIYAALGVELFGRLECSEDNPCEGLSRHATFSNFGMAFLTLFRVSTGDNWNGIMKDTLRECS 564 HSP 3 Score: 68.9366 bits (167), Expect = 9.881e-11 Identity = 61/282 (21.63%), Postives = 132/282 (46.81%), Query Frame = 1 Query: 2134 KNYLSICQQKIKTLVNDVKFQRGILIAILINTLSMGIEYHQQPVQLTQT--LEFSNIVFSILFLIEMILKLIGEGIL----GYIKNGFNLFDGIIVVLGVIELCQQGGTSGLSILRTFRLLRILKL-------VRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKFCTIE-------NNKRTCD---------RKNFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTS----------SWAALYFIALMTFGNYVLFNLLVAILVEGF 2862 +N + QK+ + F +L+ I +N +++ +E T+ L SN +F+ +F+ EM++K++ G+L Y+++ +NL DG++V++ ++++ ++G + + + L + P L+ + +I ++ + + F IF ILG+ LF KF E + K C + NFD+L +++++F + +++ W ++Y+G+ W LYFI+ + ++ + N+ V ++VE F Sbjct: 22 QNRFRVSCQKV---ITHKMFDHVVLVFIFLNCVTIALERPDIDPGSTERVFLSVSNYIFTAIFVAEMMVKVVALGLLSGEHAYLQSSWNLLDGLLVLVSLVDIVVAMASAGGAKILGVLRVLRLLRTLRPLRVISRAPGLKLVVETLISSLRPIGNIVLICCAFFIIFGILGVQLFKGKFYYCEGPDTRNISTKAQCRAAHYRWVRRKYNFDNLGQALMSLFVLSSKDGWVNIMYDGLDAVGVDQQPVQNHNPWMLLYFISFLLIVSFFVLNMFVGVVVENF 300 HSP 4 Score: 65.0846 bits (157), Expect = 1.514e-9 Identity = 33/112 (29.46%), Postives = 63/112 (56.25%), Query Frame = 1 Query: 328 ATVFHIFHQNKHPRDWCLKIITWPWFEQLSMTIIAVNCITLSMYQPCGDQNCETSKCQIMQAFDYIIFAFFTCEMVIKIIAMGFL-GDLGYFGDTWNRLDMFIVIVGSIEIL 660 A ++F R C K+IT F+ + + I +NC+T+++ +P D + +++ + +YI A F EM++K++A+G L G+ Y +WN LD +V+V ++I+ Sbjct: 13 AWALYLFSPQNRFRVSCQKVITHKMFDHVVLVFIFLNCVTIALERP--DIDPGSTERVFLSVSNYIFTAIFVAEMMVKVVALGLLSGEHAYLQSSWNLLDGLLVLVSLVDIV 122 HSP 5 Score: 54.6842 bits (130), Expect = 2.272e-6 Identity = 26/80 (32.50%), Postives = 48/80 (60.00%), Query Frame = 1 Query: 1195 NFDNIGFAWVAIFQVISMESWVDIMYYVQDA----------HSFWDWIYFVALIIIGSFFMINLCLVVIASQFSETKRRE 1404 NFDN+G A +++F + S + WV+IMY DA H+ W +YF++ ++I SFF++N+ + V+ F + ++ + Sbjct: 228 NFDNLGQALMSLFVLSSKDGWVNIMYDGLDAVGVDQQPVQNHNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHKCRQHQ 307
BLAST of Voltage-dependent T-type calcium channel subunit alpha vs. Ensembl Celegans
Match: cca-1 (Voltage-dependent T-type calcium channel subunit alpha [Source:UniProtKB/TrEMBL;Acc:A0A0K3ASP4]) HSP 1 Score: 701.434 bits (1809), Expect = 0.000e+0 Identity = 421/694 (60.66%), Postives = 506/694 (72.91%), Query Frame = 1 Query: 3664 AREKALEEPDD-----SNSESQNSSRMNNVEDPDEEDMEAMICLSKCCPQPKGIFAKRYYHSLYVFSVDNQFRQKCQHIVDKKSFDYLVLFFITLNCITLAMERPSIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILL-GHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKFYYCDGPHLQAVKTKNDCLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFHKCQE-----------NQXXXXXXXXXXXXXXXXXXXXXHLRAPLYWENYSKWRRTINSVVTSKYFDLAIAGVIGLNVITMATEFHMMPQVLKTALKVFNYFFTSTFVXXXXXXXXXXXXXRYISDKWNQLDMMIVILSIAGVVIDEVESNFMPINPTIMRVMRVLRIARVLKLLKMASGIRALLDTVIQALPQVGNXXXXXXXXXXXXXXXXVELFGRLECSDINPCVGLGRHAHFENFGMAFLTLFRIATGDNWNGIMKDTLREKCISSEDCQRNCCVSAIIAPIYFVIFXXXXXXXXXXXXXXXXXKHLEESHKMMCD------DYELEREVQRDLDEEAKE 5676 AREK LE + + E +N ++ N L K C R SL++ N R KC KK FDY VLFFI +NCITLAMERPSIPP S ER FL ++ YIFT+IFTGEM++KV++ G IG AY K GWNI+DG LV ISL+++ +L G S +IFG++RV RLLR LRPLRVI+RAPG+KLVV TL+SSL+PIGNIVLICCTFFIIFGILGVQLFKG Y+C GP + V TK DC++ +N+W N +YNFDNLGQALM+LFVLSSKDGWV IMY GIDAVGV++QP EN+NEW +IYFISFLLLV FFVLNMFVGVVVENFHKC+E + + K +R K++K R Y+ +Y R ++ +VTSKYFDLAIA VIG+NVI+MA EF+MMP LK LK NYFFT+ F LEA +KL+ALG R+ +KWN+LDM IVILSIAG++ +E E+ +PINPTI+RVMRVLRIARVLKLLKMA GIR+LLDTV +ALPQVGNLG LFFLLF+IFAALGVELFG+LECS+ +PC GLG HAHF+NFGMAFLTLFRIATGDNWNGIMKD LR+ C SS+ C+ NCCV I+AP +FVIFVL++QFVLVNVVVAVLMKHLEES+K + +E E+ + D+E E Sbjct: 1051 AREKFLEASQELKQALAEEEKRNEAKQNTF---------VRKLLKKTC------LHNRTEFSLFLMGPKNPLRIKCLQTTQKKWFDYTVLFFIGINCITLAMERPSIPPDSFERQFLHISGYIFTVIFTGEMMMKVIANGCFIGQAAYFKDGWNILDGILVVISLINIAFELLATGDSPKIFGVIRVLRLLRALRPLRVINRAPGVKLVVMTLISSLKPIGNIVLICCTFFIIFGILGVQLFKGMMYHCIGPEVGNVTTKADCIEDYRNKWVNHRYNFDNLGQALMSLFVLSSKDGWVSIMYQGIDAVGVDVQPIENYNEWRMIYFISFLLLVGFFVLNMFVGVVVENFHKCKEALEKEMREKEKEKRLKRKLKRQKFEESMAGKRKKMERNYPYYHDYGHTRLFLHGIVTSKYFDLAIAAVIGINVISMAMEFYMMPMGLKYVLKALNYFFTAVFTLEAAMKLIALGFKRFFIEKWNRLDMFIVILSIAGIIFEEFEALELPINPTIIRVMRVLRIARVLKLLKMAKGIRSLLDTVGEALPQVGNLGSLFFLLFFIFAALGVELFGKLECSEDHPCDGLGEHAHFKNFGMAFLTLFRIATGDNWNGIMKDALRDDCDSSDHCETNCCVDPILAPCFFVIFVLISQFVLVNVVVAVLMKHLEESNKRDAEGPAEPTGENIENEITKSDDDEIVE 1729 HSP 2 Score: 375.941 bits (964), Expect = 3.504e-105 Identity = 217/406 (53.45%), Postives = 281/406 (69.21%), Query Frame = 1 Query: 307 LIYHGFYATVFHIFHQNKHPRDWCLKIITWPWFEQLSMTIIAVNCITLSMYQPCGDQ-NCETSKCQIMQAFDYIIFAFFTCEMVIKIIAMGFLGDLGYFGDTWNRLDMFIVIVGSIEIL--PSTGNNIGLTAIRTIRVLRPLRAINRIPSMRIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQMWQGVLRNRCYLNLNESFRHPGLNLSSFYQINRTLFLNAVDKDFICSTDKNNGILKCSDIPPSIMLLSNNSLQICKQPARPFTDNLPTKHSCVNWNQYYTDCQPGEKNPYEGAINFDNIGFAWVAIFQVISMESWVDIMYYVQDAHSFWDWIYFVALIIIGSFFMINLCLVVIASQFSETKRRETERMWIERRRF---NSSNCS------SISKDEPQTCY 1488 L Y GF F+Q + PR W L+++ PWF++++M +I +NC+TL MY+PC D +C+T +CQI+ D IF +F EMVIKI+A+GF G Y DTWNRLD FIV+ G E + G NI LTAIRT+RVLRPLRA+NRIPSMRILV LLLDTLPMLGNVLLLCFFVFFIFGI+GVQ+W G+LRNRC +NL ++ L + ++ R ++ICS NG+ CS++PP + +L + + + T SC+NWN YY +CQ ++NP++G+++FDNIGFAWVAIF VIS+E W DIMYYVQDAHSFW+WIYFV LI+IG+FFMINLCLVVIA+QF+ETKRRETERM ER+ +S +C+ + SK+E T Y Sbjct: 100 LPYPGFAEPALRCFYQARPPRKWALQMVMSPWFDRITMAVIMINCVTLGMYRPCEDGPDCDTYRCQILDIIDNCIFVYFAFEMVIKIMALGFYGPAAYMSDTWNRLDFFIVMAGIAEFVLHEYLGGNINLTAIRTVRVLRPLRAVNRIPSMRILVNLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAGLLRNRCVINLPKTISENQSALFNNVKLTRFYIPEDTSLEYICSQPDANGLHTCSNLPPYTVDGVKCNLTLDEY-------DKVTNDSCINWNIYYNECQVMQRNPFQGSVSFDNIGFAWVAIFLVISLEGWTDIMYYVQDAHSFWNWIYFVLLIVIGAFFMINLCLVVIATQFAETKRRETERMLQERKMLLNRDSISCTGSEIGGASSKEEGDTVY 498 HSP 3 Score: 300.056 bits (767), Expect = 1.593e-81 Identity = 166/281 (59.07%), Postives = 208/281 (74.02%), Query Frame = 1 Query: 2155 QQKIKTLVNDVKFQRGILIAILINTLSMGIEYHQQPVQLTQTLEFSNIVFSILFLIEMILKLIGEGILGYIKNGFNLFDGIIVVLGVIELCQQGGTSGLSILRTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKFCTIENNKR------------TCDRKNFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTSSWAALYFIALMTFGNYVLFNLLVAILVEGFSSERLDEQKLLHN--YRQSLKKRRANNKQLRIM 2955 ++KI+ V F RGIL+AIL+NTLSMG+EYHQQP LT LE+SN+ F+ LF +EM+LK+I G+ GY+ +GFNLFDG IV L V+EL Q+G GLS+LRTFRLLRILKLVRFMPALR QL VM+RT+DNV FF LL+LFIFIFS LGM LFGCKFC + CDR NFD+ L++ VTVFQILTQEDWN VL+NGM +T+ WAALYF+ALMTFGNYVLFNLLVAILVEGF + +E++ L +Q++++ ++L ++ Sbjct: 643 REKIQKFVICDHFTRGILVAILVNTLSMGVEYHQQPEILTVILEYSNLFFTALFALEMLLKIIASGLFGYLADGFNLFDGGIVALSVLELFQEG-KGGLSVLRTFRLLRILKLVRFMPALRYQLVVMLRTMDNVTVFFGLLVLFIFIFSTLGMVLFGCKFCNHPDTGLQCTSAQVISSICECDRMNFDNFLFATVTVFQILTQEDWNMVLFNGMAQTNPWAALYFVALMTFGNYVLFNLLVAILVEGFQESKEEEKRQLEEDARKQAVEEEDERKRELELI 922 HSP 4 Score: 107.071 bits (266), Expect = 1.384e-22 Identity = 78/291 (26.80%), Postives = 138/291 (47.42%), Query Frame = 1 Query: 3862 FRQKCQHIVDKKSFDYLVLFFITLNCITLAMERPSIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKFYYCDGPH-------LQAVKTKNDCLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFHKCQENQ 4713 FR+K Q V F +L I +N +++ +E P + L +N FT +F EM++K+++ GL YL G+N+ DG +V +S+L+LF G S +LR FRLLR L+ +R + P L+ + +L ++ + + F IF LG+ LF KF C+ P Q + + +C + NFDN A + +F + +++ W +++ G+ N WA +YF++ + + + N+ V ++VE F + +E + Sbjct: 642 FREKIQKFVICDHFTRGILVAILVNTLSMGVEYHQQP--EILTVILEYSNLFFTALFALEMLLKIIASGLF----GYLADGFNLFDGGIVALSVLELFQEGKGGLS-----VLRTFRLLRILKLVRFM---PALRYQLVVMLRTMDNVTVFFGLLVLFIFIFSTLGMVLFGCKF--CNHPDTGLQCTSAQVISSICEC----------DRMNFDNFLFATVTVFQILTQEDWNMVLFNGM----------AQTNPWAALYFVALMTFGNYVLFNLLVAILVEGFQESKEEE 896 HSP 5 Score: 82.0333 bits (201), Expect = 5.222e-15 Identity = 61/175 (34.86%), Postives = 96/175 (54.86%), Query Frame = 1 Query: 3865 RQKCQHIVDKKSFDYLVLFFITLNCITLAMERP--SIPPHSKER--LFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKG 4377 R+ +V FD + + I +NC+TL M RP P R + + N IF + F EM+IK+++ G G AY+ WN +D F+V + + + LG + + I R +R LRPLR ++R P ++++V LL +L +GN++L+C F IFGI+GVQL+ G Sbjct: 120 RKWALQMVMSPWFDRITMAVIMINCVTLGMYRPCEDGPDCDTYRCQILDIIDNCIF-VYFAFEMVIKIMALGFY-GPAAYMSDTWNRLDFFIVMAGIAEFVLHEYLGGNINLTAI----RTVRVLRPLRAVNRIPSMRILVNLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAG 288 HSP 6 Score: 70.4774 bits (171), Expect = 1.575e-11 Identity = 93/326 (28.53%), Postives = 158/326 (48.47%), Query Frame = 1 Query: 4792 LYWENYSKWRRTINSVVTSKYFDLAIAGVIGLNVITMATEFHMMPQVLKTALKVFNYFFTSTFVXXXXXXXXXXXXXRYISDKWNQLDMMIVILSIAGVVIDEVESNFMPINPTIMRVMRVLRIARVLKLLKMASGIRALLDTVIQALPQVGNXXXXXXXXXXXXXXXXVELFGRLECSDINPCVGLG-------------RHAHFENFGMAFLTLFRIATGDNWNGIMKDTLREKCISSEDCQRNCCVSAIIAPIYFVIFXXXXXXXXXXXXXXXXXKHLEESHKMMCDDYELEREVQRDLDEEAKELAREKQLKDEENNENTLI 5730 L+W +R I V +F I I +N ++M E+H P++L L+ N FFT+ F LE LLK++A GL Y++D +N D IV LS+ + + + V+R R+ R+LKL++ +R L +++ + V L L +IF+ LG+ LFG C+ +P GL +F+NF A +T+F+I T ++WN ++ + + + + A +YFV + +VL N++VA+L++ +ES + E +R L+E+A++ A E++ DE E LI Sbjct: 639 LWW-----FREKIQKFVICDHFTRGILVAILVNTLSMGVEYHQQPEILTVILEYSNLFFTALFALEMLLKIIASGLFGYLADGFNLFDGGIVALSVLELFQE---------GKGGLSVLRTFRLLRILKLVRFMPALRYQLVVMLRTMDNVTVFFGLLVLFIFIFSTLGMVLFGCKFCN--HPDTGLQCTSAQVISSICECDRMNFDNFLFATVTVFQILTQEDWNMVLFNGMAQ--------------TNPWAALYFVALMTFGNYVLFNLLVAILVEGFQES----------KEEEKRQLEEDARKQAVEEE--DERKRELELI 922 HSP 7 Score: 68.5514 bits (166), Expect = 7.162e-11 Identity = 54/211 (25.59%), Postives = 99/211 (46.92%), Query Frame = 1 Query: 2164 IKTLVNDVKFQRGILIAILINTLSMGIEYHQQPVQLTQTLEFSNIVFSILFLIEMILKLIGEGILGYIKNGFNLFDGIIVVLGVIELCQQG--------GTSGLSILRTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKFCTIENNKRTCD----RKNFDSLLWSIVTVFQILTQEDWNTVLYNGM 2760 + +V F I I IN +SM +E++ P+ L L+ N F+ +F +E +KLI G + +N D IV+L + + + + + ++R R+ R+LKL++ +R L + + V +L L FIF+ LG+ LFG C+ CD +F + + +T+F+I T ++WN ++ + + Sbjct: 1441 LHGIVTSKYFDLAIAAVIGINVISMAMEFYMMPMGLKYVLKALNYFFTAVFTLEAAMKLIALGFKRFFIEKWNRLDMFIVILSIAGIIFEEFEALELPINPTIIRVMRVLRIARVLKLLKMAKGIRSLLDTVGEALPQVGNLGSLFFLLFFIFAALGVELFGKLECS---EDHPCDGLGEHAHFKNFGMAFLTLFRIATGDNWNGIMKDAL 1648 HSP 8 Score: 67.3958 bits (163), Expect = 1.313e-10 Identity = 69/278 (24.82%), Postives = 129/278 (46.40%), Query Frame = 1 Query: 2161 KIKTLVNDVK--FQRGILIAILINTLSMGIEYHQQPVQL--TQTLEFSNIVFSILFLIEMILKLIGEGIL----GYIKNGFNLFDGIIVVLGVIELCQQGGTSGLSILRTFRLL---------RILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFG---------------CKFCTIEN--NKRTCDRKNFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTS----------SWAALYFIALMTFGNYVLFNLLVAILVEGF 2862 +IK L K F +L I IN +++ +E P Q L S +F+++F EM++K+I G Y K+G+N+ DGI+VV+ +I + + +G S + F ++ R L+++ P ++ + +I ++ + + F IF ILG+ LF K IE+ NK R NFD+L +++++F + +++ W +++Y G+ W +YFI+ + + + N+ V ++VE F Sbjct: 1108 RIKCLQTTQKKWFDYTVLFFIGINCITLAMERPSIPPDSFERQFLHISGYIFTVIFTGEMMMKVIANGCFIGQAAYFKDGWNILDGILVVISLINIAFELLATGDSP-KIFGVIRVLRLLRALRPLRVINRAPGVKLVVMTLISSLKPIGNIVLICCTFFIIFGILGVQLFKGMMYHCIGPEVGNVTTKADCIEDYRNKWVNHRYNFDNLGQALMSLFVLSSKDGWVSIMYQGIDAVGVDVQPIENYNEWRMIYFISFLLLVGFFVLNMFVGVVVENF 1384 HSP 9 Score: 65.4698 bits (158), Expect = 5.819e-10 Identity = 44/122 (36.07%), Postives = 66/122 (54.10%), Query Frame = 1 Query: 331 TVFHIFHQN-KHP-RDWCLKIITWPWFEQLSMTIIAVNCITLSMYQPCGDQNCETSKCQIMQAFDYIIFAFFTCEMVIKIIAMG-FLGDLGYFGDTWNRLDMFIVIVGSIEI---LPSTGNN 678 T F +F K+P R CL+ WF+ + I +NCITL+M +P ++ + Q + YI FT EM++K+IA G F+G YF D WN LD +V++ I I L +TG++ Sbjct: 1094 TEFSLFLMGPKNPLRIKCLQTTQKKWFDYTVLFFIGINCITLAMERPSIPP--DSFERQFLHISGYIFTVIFTGEMMMKVIANGCFIGQAAYFKDGWNILDGILVVISLINIAFELLATGDS 1213 HSP 10 Score: 64.3142 bits (155), Expect = 1.131e-9 Identity = 44/136 (32.35%), Postives = 69/136 (50.74%), Query Frame = 1 Query: 346 FHQNKHPRDWCLKIITWPWFEQLSMTIIAVNCITLSM---YQPCGDQNCETSKCQIMQAFDYIIFAFFTCEMVIKIIAMGFLGDLGYFGDTWNRLDMFIVIVGSIEILPSTGNNIGL----TAIRTIRVLRPLRAI 732 +H H R + I+T +F+ +I +N I+++M P G + +++A +Y A FT E +K+IA+GF +F + WNRLDMFIVI+ I+ + L T IR +RVLR R + Sbjct: 1431 YHDYGHTRLFLHGIVTSKYFDLAIAAVIGINVISMAMEFYMMPMGLK-------YVLKALNYFFTAVFTLEAAMKLIALGFKR---FFIEKWNRLDMFIVILSIAGIIFEEFEALELPINPTIIRVMRVLRIARVL 1556 HSP 11 Score: 57.7658 bits (138), Expect = 1.081e-7 Identity = 25/81 (30.86%), Postives = 47/81 (58.02%), Query Frame = 1 Query: 1192 INFDNIGFAWVAIFQVISMESWVDIMYYVQDAHSFWDWIYFVALIIIGSFFMINLCLVVIASQFSETKRRETERMWIERRR 1434 +NFDN FA V +FQ+++ E W +++ + W +YFVAL+ G++ + NL + ++ F E+K E ++ + R+ Sbjct: 826 MNFDNFLFATVTVFQILTQEDWNMVLFNGMAQTNPWAALYFVALMTFGNYVLFNLLVAILVEGFQESKEEEKRQLEEDARK 906 HSP 12 Score: 54.299 bits (129), Expect = 1.260e-6 Identity = 29/96 (30.21%), Postives = 53/96 (55.21%), Query Frame = 1 Query: 4426 NDCLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFHKCQENQ 4713 N+C +N ++ +FDN+G A +A+F++ S +GW IMY DA H+ W IYF+ +++ AFF++N+ + V+ F + + + Sbjct: 377 NECQVMQRNPFQGS-VSFDNIGFAWVAIFLVISLEGWTDIMYYVQDA----------HSFWNWIYFVLLIVIGAFFMINLCLVVIATQFAETKRRE 461
BLAST of Voltage-dependent T-type calcium channel subunit alpha vs. Ensembl Celegans
Match: cca-1 (Voltage-dependent T-type calcium channel subunit alpha [Source:UniProtKB/TrEMBL;Acc:A0A0K3ASP4]) HSP 1 Score: 701.434 bits (1809), Expect = 0.000e+0 Identity = 421/694 (60.66%), Postives = 506/694 (72.91%), Query Frame = 1 Query: 3664 AREKALEEPDD-----SNSESQNSSRMNNVEDPDEEDMEAMICLSKCCPQPKGIFAKRYYHSLYVFSVDNQFRQKCQHIVDKKSFDYLVLFFITLNCITLAMERPSIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILL-GHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKFYYCDGPHLQAVKTKNDCLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFHKCQE-----------NQXXXXXXXXXXXXXXXXXXXXXHLRAPLYWENYSKWRRTINSVVTSKYFDLAIAGVIGLNVITMATEFHMMPQVLKTALKVFNYFFTSTFVXXXXXXXXXXXXXRYISDKWNQLDMMIVILSIAGVVIDEVESNFMPINPTIMRVMRVLRIARVLKLLKMASGIRALLDTVIQALPQVGNXXXXXXXXXXXXXXXXVELFGRLECSDINPCVGLGRHAHFENFGMAFLTLFRIATGDNWNGIMKDTLREKCISSEDCQRNCCVSAIIAPIYFVIFXXXXXXXXXXXXXXXXXKHLEESHKMMCD------DYELEREVQRDLDEEAKE 5676 AREK LE + + E +N ++ N L K C R SL++ N R KC KK FDY VLFFI +NCITLAMERPSIPP S ER FL ++ YIFT+IFTGEM++KV++ G IG AY K GWNI+DG LV ISL+++ +L G S +IFG++RV RLLR LRPLRVI+RAPG+KLVV TL+SSL+PIGNIVLICCTFFIIFGILGVQLFKG Y+C GP + V TK DC++ +N+W N +YNFDNLGQALM+LFVLSSKDGWV IMY GIDAVGV++QP EN+NEW +IYFISFLLLV FFVLNMFVGVVVENFHKC+E + + K +R K++K R Y+ +Y R ++ +VTSKYFDLAIA VIG+NVI+MA EF+MMP LK LK NYFFT+ F LEA +KL+ALG R+ +KWN+LDM IVILSIAG++ +E E+ +PINPTI+RVMRVLRIARVLKLLKMA GIR+LLDTV +ALPQVGNLG LFFLLF+IFAALGVELFG+LECS+ +PC GLG HAHF+NFGMAFLTLFRIATGDNWNGIMKD LR+ C SS+ C+ NCCV I+AP +FVIFVL++QFVLVNVVVAVLMKHLEES+K + +E E+ + D+E E Sbjct: 1051 AREKFLEASQELKQALAEEEKRNEAKQNTF---------VRKLLKKTC------LHNRTEFSLFLMGPKNPLRIKCLQTTQKKWFDYTVLFFIGINCITLAMERPSIPPDSFERQFLHISGYIFTVIFTGEMMMKVIANGCFIGQAAYFKDGWNILDGILVVISLINIAFELLATGDSPKIFGVIRVLRLLRALRPLRVINRAPGVKLVVMTLISSLKPIGNIVLICCTFFIIFGILGVQLFKGMMYHCIGPEVGNVTTKADCIEDYRNKWVNHRYNFDNLGQALMSLFVLSSKDGWVSIMYQGIDAVGVDVQPIENYNEWRMIYFISFLLLVGFFVLNMFVGVVVENFHKCKEALEKEMREKEKEKRLKRKLKRQKFEESMAGKRKKMERNYPYYHDYGHTRLFLHGIVTSKYFDLAIAAVIGINVISMAMEFYMMPMGLKYVLKALNYFFTAVFTLEAAMKLIALGFKRFFIEKWNRLDMFIVILSIAGIIFEEFEALELPINPTIIRVMRVLRIARVLKLLKMAKGIRSLLDTVGEALPQVGNLGSLFFLLFFIFAALGVELFGKLECSEDHPCDGLGEHAHFKNFGMAFLTLFRIATGDNWNGIMKDALRDDCDSSDHCETNCCVDPILAPCFFVIFVLISQFVLVNVVVAVLMKHLEESNKRDAEGPAEPTGENIENEITKSDDDEIVE 1729 HSP 2 Score: 375.941 bits (964), Expect = 3.504e-105 Identity = 217/406 (53.45%), Postives = 281/406 (69.21%), Query Frame = 1 Query: 307 LIYHGFYATVFHIFHQNKHPRDWCLKIITWPWFEQLSMTIIAVNCITLSMYQPCGDQ-NCETSKCQIMQAFDYIIFAFFTCEMVIKIIAMGFLGDLGYFGDTWNRLDMFIVIVGSIEIL--PSTGNNIGLTAIRTIRVLRPLRAINRIPSMRIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQMWQGVLRNRCYLNLNESFRHPGLNLSSFYQINRTLFLNAVDKDFICSTDKNNGILKCSDIPPSIMLLSNNSLQICKQPARPFTDNLPTKHSCVNWNQYYTDCQPGEKNPYEGAINFDNIGFAWVAIFQVISMESWVDIMYYVQDAHSFWDWIYFVALIIIGSFFMINLCLVVIASQFSETKRRETERMWIERRRF---NSSNCS------SISKDEPQTCY 1488 L Y GF F+Q + PR W L+++ PWF++++M +I +NC+TL MY+PC D +C+T +CQI+ D IF +F EMVIKI+A+GF G Y DTWNRLD FIV+ G E + G NI LTAIRT+RVLRPLRA+NRIPSMRILV LLLDTLPMLGNVLLLCFFVFFIFGI+GVQ+W G+LRNRC +NL ++ L + ++ R ++ICS NG+ CS++PP + +L + + + T SC+NWN YY +CQ ++NP++G+++FDNIGFAWVAIF VIS+E W DIMYYVQDAHSFW+WIYFV LI+IG+FFMINLCLVVIA+QF+ETKRRETERM ER+ +S +C+ + SK+E T Y Sbjct: 100 LPYPGFAEPALRCFYQARPPRKWALQMVMSPWFDRITMAVIMINCVTLGMYRPCEDGPDCDTYRCQILDIIDNCIFVYFAFEMVIKIMALGFYGPAAYMSDTWNRLDFFIVMAGIAEFVLHEYLGGNINLTAIRTVRVLRPLRAVNRIPSMRILVNLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAGLLRNRCVINLPKTISENQSALFNNVKLTRFYIPEDTSLEYICSQPDANGLHTCSNLPPYTVDGVKCNLTLDEY-------DKVTNDSCINWNIYYNECQVMQRNPFQGSVSFDNIGFAWVAIFLVISLEGWTDIMYYVQDAHSFWNWIYFVLLIVIGAFFMINLCLVVIATQFAETKRRETERMLQERKMLLNRDSISCTGSEIGGASSKEEGDTVY 498 HSP 3 Score: 300.056 bits (767), Expect = 1.593e-81 Identity = 166/281 (59.07%), Postives = 208/281 (74.02%), Query Frame = 1 Query: 2155 QQKIKTLVNDVKFQRGILIAILINTLSMGIEYHQQPVQLTQTLEFSNIVFSILFLIEMILKLIGEGILGYIKNGFNLFDGIIVVLGVIELCQQGGTSGLSILRTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKFCTIENNKR------------TCDRKNFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTSSWAALYFIALMTFGNYVLFNLLVAILVEGFSSERLDEQKLLHN--YRQSLKKRRANNKQLRIM 2955 ++KI+ V F RGIL+AIL+NTLSMG+EYHQQP LT LE+SN+ F+ LF +EM+LK+I G+ GY+ +GFNLFDG IV L V+EL Q+G GLS+LRTFRLLRILKLVRFMPALR QL VM+RT+DNV FF LL+LFIFIFS LGM LFGCKFC + CDR NFD+ L++ VTVFQILTQEDWN VL+NGM +T+ WAALYF+ALMTFGNYVLFNLLVAILVEGF + +E++ L +Q++++ ++L ++ Sbjct: 643 REKIQKFVICDHFTRGILVAILVNTLSMGVEYHQQPEILTVILEYSNLFFTALFALEMLLKIIASGLFGYLADGFNLFDGGIVALSVLELFQEG-KGGLSVLRTFRLLRILKLVRFMPALRYQLVVMLRTMDNVTVFFGLLVLFIFIFSTLGMVLFGCKFCNHPDTGLQCTSAQVISSICECDRMNFDNFLFATVTVFQILTQEDWNMVLFNGMAQTNPWAALYFVALMTFGNYVLFNLLVAILVEGFQESKEEEKRQLEEDARKQAVEEEDERKRELELI 922 HSP 4 Score: 107.071 bits (266), Expect = 1.384e-22 Identity = 78/291 (26.80%), Postives = 138/291 (47.42%), Query Frame = 1 Query: 3862 FRQKCQHIVDKKSFDYLVLFFITLNCITLAMERPSIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKFYYCDGPH-------LQAVKTKNDCLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFHKCQENQ 4713 FR+K Q V F +L I +N +++ +E P + L +N FT +F EM++K+++ GL YL G+N+ DG +V +S+L+LF G S +LR FRLLR L+ +R + P L+ + +L ++ + + F IF LG+ LF KF C+ P Q + + +C + NFDN A + +F + +++ W +++ G+ N WA +YF++ + + + N+ V ++VE F + +E + Sbjct: 642 FREKIQKFVICDHFTRGILVAILVNTLSMGVEYHQQP--EILTVILEYSNLFFTALFALEMLLKIIASGLF----GYLADGFNLFDGGIVALSVLELFQEGKGGLS-----VLRTFRLLRILKLVRFM---PALRYQLVVMLRTMDNVTVFFGLLVLFIFIFSTLGMVLFGCKF--CNHPDTGLQCTSAQVISSICEC----------DRMNFDNFLFATVTVFQILTQEDWNMVLFNGM----------AQTNPWAALYFVALMTFGNYVLFNLLVAILVEGFQESKEEE 896 HSP 5 Score: 82.0333 bits (201), Expect = 5.222e-15 Identity = 61/175 (34.86%), Postives = 96/175 (54.86%), Query Frame = 1 Query: 3865 RQKCQHIVDKKSFDYLVLFFITLNCITLAMERP--SIPPHSKER--LFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKG 4377 R+ +V FD + + I +NC+TL M RP P R + + N IF + F EM+IK+++ G G AY+ WN +D F+V + + + LG + + I R +R LRPLR ++R P ++++V LL +L +GN++L+C F IFGI+GVQL+ G Sbjct: 120 RKWALQMVMSPWFDRITMAVIMINCVTLGMYRPCEDGPDCDTYRCQILDIIDNCIF-VYFAFEMVIKIMALGFY-GPAAYMSDTWNRLDFFIVMAGIAEFVLHEYLGGNINLTAI----RTVRVLRPLRAVNRIPSMRILVNLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAG 288 HSP 6 Score: 70.4774 bits (171), Expect = 1.575e-11 Identity = 93/326 (28.53%), Postives = 158/326 (48.47%), Query Frame = 1 Query: 4792 LYWENYSKWRRTINSVVTSKYFDLAIAGVIGLNVITMATEFHMMPQVLKTALKVFNYFFTSTFVXXXXXXXXXXXXXRYISDKWNQLDMMIVILSIAGVVIDEVESNFMPINPTIMRVMRVLRIARVLKLLKMASGIRALLDTVIQALPQVGNXXXXXXXXXXXXXXXXVELFGRLECSDINPCVGLG-------------RHAHFENFGMAFLTLFRIATGDNWNGIMKDTLREKCISSEDCQRNCCVSAIIAPIYFVIFXXXXXXXXXXXXXXXXXKHLEESHKMMCDDYELEREVQRDLDEEAKELAREKQLKDEENNENTLI 5730 L+W +R I V +F I I +N ++M E+H P++L L+ N FFT+ F LE LLK++A GL Y++D +N D IV LS+ + + + V+R R+ R+LKL++ +R L +++ + V L L +IF+ LG+ LFG C+ +P GL +F+NF A +T+F+I T ++WN ++ + + + + A +YFV + +VL N++VA+L++ +ES + E +R L+E+A++ A E++ DE E LI Sbjct: 639 LWW-----FREKIQKFVICDHFTRGILVAILVNTLSMGVEYHQQPEILTVILEYSNLFFTALFALEMLLKIIASGLFGYLADGFNLFDGGIVALSVLELFQE---------GKGGLSVLRTFRLLRILKLVRFMPALRYQLVVMLRTMDNVTVFFGLLVLFIFIFSTLGMVLFGCKFCN--HPDTGLQCTSAQVISSICECDRMNFDNFLFATVTVFQILTQEDWNMVLFNGMAQ--------------TNPWAALYFVALMTFGNYVLFNLLVAILVEGFQES----------KEEEKRQLEEDARKQAVEEE--DERKRELELI 922 HSP 7 Score: 68.5514 bits (166), Expect = 7.162e-11 Identity = 54/211 (25.59%), Postives = 99/211 (46.92%), Query Frame = 1 Query: 2164 IKTLVNDVKFQRGILIAILINTLSMGIEYHQQPVQLTQTLEFSNIVFSILFLIEMILKLIGEGILGYIKNGFNLFDGIIVVLGVIELCQQG--------GTSGLSILRTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKFCTIENNKRTCD----RKNFDSLLWSIVTVFQILTQEDWNTVLYNGM 2760 + +V F I I IN +SM +E++ P+ L L+ N F+ +F +E +KLI G + +N D IV+L + + + + + ++R R+ R+LKL++ +R L + + V +L L FIF+ LG+ LFG C+ CD +F + + +T+F+I T ++WN ++ + + Sbjct: 1441 LHGIVTSKYFDLAIAAVIGINVISMAMEFYMMPMGLKYVLKALNYFFTAVFTLEAAMKLIALGFKRFFIEKWNRLDMFIVILSIAGIIFEEFEALELPINPTIIRVMRVLRIARVLKLLKMAKGIRSLLDTVGEALPQVGNLGSLFFLLFFIFAALGVELFGKLECS---EDHPCDGLGEHAHFKNFGMAFLTLFRIATGDNWNGIMKDAL 1648 HSP 8 Score: 67.3958 bits (163), Expect = 1.313e-10 Identity = 69/278 (24.82%), Postives = 129/278 (46.40%), Query Frame = 1 Query: 2161 KIKTLVNDVK--FQRGILIAILINTLSMGIEYHQQPVQL--TQTLEFSNIVFSILFLIEMILKLIGEGIL----GYIKNGFNLFDGIIVVLGVIELCQQGGTSGLSILRTFRLL---------RILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFG---------------CKFCTIEN--NKRTCDRKNFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTS----------SWAALYFIALMTFGNYVLFNLLVAILVEGF 2862 +IK L K F +L I IN +++ +E P Q L S +F+++F EM++K+I G Y K+G+N+ DGI+VV+ +I + + +G S + F ++ R L+++ P ++ + +I ++ + + F IF ILG+ LF K IE+ NK R NFD+L +++++F + +++ W +++Y G+ W +YFI+ + + + N+ V ++VE F Sbjct: 1108 RIKCLQTTQKKWFDYTVLFFIGINCITLAMERPSIPPDSFERQFLHISGYIFTVIFTGEMMMKVIANGCFIGQAAYFKDGWNILDGILVVISLINIAFELLATGDSP-KIFGVIRVLRLLRALRPLRVINRAPGVKLVVMTLISSLKPIGNIVLICCTFFIIFGILGVQLFKGMMYHCIGPEVGNVTTKADCIEDYRNKWVNHRYNFDNLGQALMSLFVLSSKDGWVSIMYQGIDAVGVDVQPIENYNEWRMIYFISFLLLVGFFVLNMFVGVVVENF 1384 HSP 9 Score: 65.4698 bits (158), Expect = 5.819e-10 Identity = 44/122 (36.07%), Postives = 66/122 (54.10%), Query Frame = 1 Query: 331 TVFHIFHQN-KHP-RDWCLKIITWPWFEQLSMTIIAVNCITLSMYQPCGDQNCETSKCQIMQAFDYIIFAFFTCEMVIKIIAMG-FLGDLGYFGDTWNRLDMFIVIVGSIEI---LPSTGNN 678 T F +F K+P R CL+ WF+ + I +NCITL+M +P ++ + Q + YI FT EM++K+IA G F+G YF D WN LD +V++ I I L +TG++ Sbjct: 1094 TEFSLFLMGPKNPLRIKCLQTTQKKWFDYTVLFFIGINCITLAMERPSIPP--DSFERQFLHISGYIFTVIFTGEMMMKVIANGCFIGQAAYFKDGWNILDGILVVISLINIAFELLATGDS 1213 HSP 10 Score: 64.3142 bits (155), Expect = 1.131e-9 Identity = 44/136 (32.35%), Postives = 69/136 (50.74%), Query Frame = 1 Query: 346 FHQNKHPRDWCLKIITWPWFEQLSMTIIAVNCITLSM---YQPCGDQNCETSKCQIMQAFDYIIFAFFTCEMVIKIIAMGFLGDLGYFGDTWNRLDMFIVIVGSIEILPSTGNNIGL----TAIRTIRVLRPLRAI 732 +H H R + I+T +F+ +I +N I+++M P G + +++A +Y A FT E +K+IA+GF +F + WNRLDMFIVI+ I+ + L T IR +RVLR R + Sbjct: 1431 YHDYGHTRLFLHGIVTSKYFDLAIAAVIGINVISMAMEFYMMPMGLK-------YVLKALNYFFTAVFTLEAAMKLIALGFKR---FFIEKWNRLDMFIVILSIAGIIFEEFEALELPINPTIIRVMRVLRIARVL 1556 HSP 11 Score: 57.7658 bits (138), Expect = 1.081e-7 Identity = 25/81 (30.86%), Postives = 47/81 (58.02%), Query Frame = 1 Query: 1192 INFDNIGFAWVAIFQVISMESWVDIMYYVQDAHSFWDWIYFVALIIIGSFFMINLCLVVIASQFSETKRRETERMWIERRR 1434 +NFDN FA V +FQ+++ E W +++ + W +YFVAL+ G++ + NL + ++ F E+K E ++ + R+ Sbjct: 826 MNFDNFLFATVTVFQILTQEDWNMVLFNGMAQTNPWAALYFVALMTFGNYVLFNLLVAILVEGFQESKEEEKRQLEEDARK 906 HSP 12 Score: 54.299 bits (129), Expect = 1.260e-6 Identity = 29/96 (30.21%), Postives = 53/96 (55.21%), Query Frame = 1 Query: 4426 NDCLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFHKCQENQ 4713 N+C +N ++ +FDN+G A +A+F++ S +GW IMY DA H+ W IYF+ +++ AFF++N+ + V+ F + + + Sbjct: 377 NECQVMQRNPFQGS-VSFDNIGFAWVAIFLVISLEGWTDIMYYVQDA----------HSFWNWIYFVLLIVIGAFFMINLCLVVIATQFAETKRRE 461
BLAST of Voltage-dependent T-type calcium channel subunit alpha vs. Ensembl Celegans
Match: cca-1 (Voltage-dependent T-type calcium channel subunit alpha [Source:UniProtKB/TrEMBL;Acc:A0A0K3ASP4]) HSP 1 Score: 701.434 bits (1809), Expect = 0.000e+0 Identity = 421/694 (60.66%), Postives = 506/694 (72.91%), Query Frame = 1 Query: 3664 AREKALEEPDD-----SNSESQNSSRMNNVEDPDEEDMEAMICLSKCCPQPKGIFAKRYYHSLYVFSVDNQFRQKCQHIVDKKSFDYLVLFFITLNCITLAMERPSIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILL-GHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKFYYCDGPHLQAVKTKNDCLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFHKCQE-----------NQXXXXXXXXXXXXXXXXXXXXXHLRAPLYWENYSKWRRTINSVVTSKYFDLAIAGVIGLNVITMATEFHMMPQVLKTALKVFNYFFTSTFVXXXXXXXXXXXXXRYISDKWNQLDMMIVILSIAGVVIDEVESNFMPINPTIMRVMRVLRIARVLKLLKMASGIRALLDTVIQALPQVGNXXXXXXXXXXXXXXXXVELFGRLECSDINPCVGLGRHAHFENFGMAFLTLFRIATGDNWNGIMKDTLREKCISSEDCQRNCCVSAIIAPIYFVIFXXXXXXXXXXXXXXXXXKHLEESHKMMCD------DYELEREVQRDLDEEAKE 5676 AREK LE + + E +N ++ N L K C R SL++ N R KC KK FDY VLFFI +NCITLAMERPSIPP S ER FL ++ YIFT+IFTGEM++KV++ G IG AY K GWNI+DG LV ISL+++ +L G S +IFG++RV RLLR LRPLRVI+RAPG+KLVV TL+SSL+PIGNIVLICCTFFIIFGILGVQLFKG Y+C GP + V TK DC++ +N+W N +YNFDNLGQALM+LFVLSSKDGWV IMY GIDAVGV++QP EN+NEW +IYFISFLLLV FFVLNMFVGVVVENFHKC+E + + K +R K++K R Y+ +Y R ++ +VTSKYFDLAIA VIG+NVI+MA EF+MMP LK LK NYFFT+ F LEA +KL+ALG R+ +KWN+LDM IVILSIAG++ +E E+ +PINPTI+RVMRVLRIARVLKLLKMA GIR+LLDTV +ALPQVGNLG LFFLLF+IFAALGVELFG+LECS+ +PC GLG HAHF+NFGMAFLTLFRIATGDNWNGIMKD LR+ C SS+ C+ NCCV I+AP +FVIFVL++QFVLVNVVVAVLMKHLEES+K + +E E+ + D+E E Sbjct: 1051 AREKFLEASQELKQALAEEEKRNEAKQNTF---------VRKLLKKTC------LHNRTEFSLFLMGPKNPLRIKCLQTTQKKWFDYTVLFFIGINCITLAMERPSIPPDSFERQFLHISGYIFTVIFTGEMMMKVIANGCFIGQAAYFKDGWNILDGILVVISLINIAFELLATGDSPKIFGVIRVLRLLRALRPLRVINRAPGVKLVVMTLISSLKPIGNIVLICCTFFIIFGILGVQLFKGMMYHCIGPEVGNVTTKADCIEDYRNKWVNHRYNFDNLGQALMSLFVLSSKDGWVSIMYQGIDAVGVDVQPIENYNEWRMIYFISFLLLVGFFVLNMFVGVVVENFHKCKEALEKEMREKEKEKRLKRKLKRQKFEESMAGKRKKMERNYPYYHDYGHTRLFLHGIVTSKYFDLAIAAVIGINVISMAMEFYMMPMGLKYVLKALNYFFTAVFTLEAAMKLIALGFKRFFIEKWNRLDMFIVILSIAGIIFEEFEALELPINPTIIRVMRVLRIARVLKLLKMAKGIRSLLDTVGEALPQVGNLGSLFFLLFFIFAALGVELFGKLECSEDHPCDGLGEHAHFKNFGMAFLTLFRIATGDNWNGIMKDALRDDCDSSDHCETNCCVDPILAPCFFVIFVLISQFVLVNVVVAVLMKHLEESNKRDAEGPAEPTGENIENEITKSDDDEIVE 1729 HSP 2 Score: 375.941 bits (964), Expect = 3.504e-105 Identity = 217/406 (53.45%), Postives = 281/406 (69.21%), Query Frame = 1 Query: 307 LIYHGFYATVFHIFHQNKHPRDWCLKIITWPWFEQLSMTIIAVNCITLSMYQPCGDQ-NCETSKCQIMQAFDYIIFAFFTCEMVIKIIAMGFLGDLGYFGDTWNRLDMFIVIVGSIEIL--PSTGNNIGLTAIRTIRVLRPLRAINRIPSMRIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQMWQGVLRNRCYLNLNESFRHPGLNLSSFYQINRTLFLNAVDKDFICSTDKNNGILKCSDIPPSIMLLSNNSLQICKQPARPFTDNLPTKHSCVNWNQYYTDCQPGEKNPYEGAINFDNIGFAWVAIFQVISMESWVDIMYYVQDAHSFWDWIYFVALIIIGSFFMINLCLVVIASQFSETKRRETERMWIERRRF---NSSNCS------SISKDEPQTCY 1488 L Y GF F+Q + PR W L+++ PWF++++M +I +NC+TL MY+PC D +C+T +CQI+ D IF +F EMVIKI+A+GF G Y DTWNRLD FIV+ G E + G NI LTAIRT+RVLRPLRA+NRIPSMRILV LLLDTLPMLGNVLLLCFFVFFIFGI+GVQ+W G+LRNRC +NL ++ L + ++ R ++ICS NG+ CS++PP + +L + + + T SC+NWN YY +CQ ++NP++G+++FDNIGFAWVAIF VIS+E W DIMYYVQDAHSFW+WIYFV LI+IG+FFMINLCLVVIA+QF+ETKRRETERM ER+ +S +C+ + SK+E T Y Sbjct: 100 LPYPGFAEPALRCFYQARPPRKWALQMVMSPWFDRITMAVIMINCVTLGMYRPCEDGPDCDTYRCQILDIIDNCIFVYFAFEMVIKIMALGFYGPAAYMSDTWNRLDFFIVMAGIAEFVLHEYLGGNINLTAIRTVRVLRPLRAVNRIPSMRILVNLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAGLLRNRCVINLPKTISENQSALFNNVKLTRFYIPEDTSLEYICSQPDANGLHTCSNLPPYTVDGVKCNLTLDEY-------DKVTNDSCINWNIYYNECQVMQRNPFQGSVSFDNIGFAWVAIFLVISLEGWTDIMYYVQDAHSFWNWIYFVLLIVIGAFFMINLCLVVIATQFAETKRRETERMLQERKMLLNRDSISCTGSEIGGASSKEEGDTVY 498 HSP 3 Score: 300.056 bits (767), Expect = 1.593e-81 Identity = 166/281 (59.07%), Postives = 208/281 (74.02%), Query Frame = 1 Query: 2155 QQKIKTLVNDVKFQRGILIAILINTLSMGIEYHQQPVQLTQTLEFSNIVFSILFLIEMILKLIGEGILGYIKNGFNLFDGIIVVLGVIELCQQGGTSGLSILRTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKFCTIENNKR------------TCDRKNFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTSSWAALYFIALMTFGNYVLFNLLVAILVEGFSSERLDEQKLLHN--YRQSLKKRRANNKQLRIM 2955 ++KI+ V F RGIL+AIL+NTLSMG+EYHQQP LT LE+SN+ F+ LF +EM+LK+I G+ GY+ +GFNLFDG IV L V+EL Q+G GLS+LRTFRLLRILKLVRFMPALR QL VM+RT+DNV FF LL+LFIFIFS LGM LFGCKFC + CDR NFD+ L++ VTVFQILTQEDWN VL+NGM +T+ WAALYF+ALMTFGNYVLFNLLVAILVEGF + +E++ L +Q++++ ++L ++ Sbjct: 643 REKIQKFVICDHFTRGILVAILVNTLSMGVEYHQQPEILTVILEYSNLFFTALFALEMLLKIIASGLFGYLADGFNLFDGGIVALSVLELFQEG-KGGLSVLRTFRLLRILKLVRFMPALRYQLVVMLRTMDNVTVFFGLLVLFIFIFSTLGMVLFGCKFCNHPDTGLQCTSAQVISSICECDRMNFDNFLFATVTVFQILTQEDWNMVLFNGMAQTNPWAALYFVALMTFGNYVLFNLLVAILVEGFQESKEEEKRQLEEDARKQAVEEEDERKRELELI 922 HSP 4 Score: 107.071 bits (266), Expect = 1.384e-22 Identity = 78/291 (26.80%), Postives = 138/291 (47.42%), Query Frame = 1 Query: 3862 FRQKCQHIVDKKSFDYLVLFFITLNCITLAMERPSIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKFYYCDGPH-------LQAVKTKNDCLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFHKCQENQ 4713 FR+K Q V F +L I +N +++ +E P + L +N FT +F EM++K+++ GL YL G+N+ DG +V +S+L+LF G S +LR FRLLR L+ +R + P L+ + +L ++ + + F IF LG+ LF KF C+ P Q + + +C + NFDN A + +F + +++ W +++ G+ N WA +YF++ + + + N+ V ++VE F + +E + Sbjct: 642 FREKIQKFVICDHFTRGILVAILVNTLSMGVEYHQQP--EILTVILEYSNLFFTALFALEMLLKIIASGLF----GYLADGFNLFDGGIVALSVLELFQEGKGGLS-----VLRTFRLLRILKLVRFM---PALRYQLVVMLRTMDNVTVFFGLLVLFIFIFSTLGMVLFGCKF--CNHPDTGLQCTSAQVISSICEC----------DRMNFDNFLFATVTVFQILTQEDWNMVLFNGM----------AQTNPWAALYFVALMTFGNYVLFNLLVAILVEGFQESKEEE 896 HSP 5 Score: 82.0333 bits (201), Expect = 5.222e-15 Identity = 61/175 (34.86%), Postives = 96/175 (54.86%), Query Frame = 1 Query: 3865 RQKCQHIVDKKSFDYLVLFFITLNCITLAMERP--SIPPHSKER--LFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKG 4377 R+ +V FD + + I +NC+TL M RP P R + + N IF + F EM+IK+++ G G AY+ WN +D F+V + + + LG + + I R +R LRPLR ++R P ++++V LL +L +GN++L+C F IFGI+GVQL+ G Sbjct: 120 RKWALQMVMSPWFDRITMAVIMINCVTLGMYRPCEDGPDCDTYRCQILDIIDNCIF-VYFAFEMVIKIMALGFY-GPAAYMSDTWNRLDFFIVMAGIAEFVLHEYLGGNINLTAI----RTVRVLRPLRAVNRIPSMRILVNLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAG 288 HSP 6 Score: 70.4774 bits (171), Expect = 1.575e-11 Identity = 93/326 (28.53%), Postives = 158/326 (48.47%), Query Frame = 1 Query: 4792 LYWENYSKWRRTINSVVTSKYFDLAIAGVIGLNVITMATEFHMMPQVLKTALKVFNYFFTSTFVXXXXXXXXXXXXXRYISDKWNQLDMMIVILSIAGVVIDEVESNFMPINPTIMRVMRVLRIARVLKLLKMASGIRALLDTVIQALPQVGNXXXXXXXXXXXXXXXXVELFGRLECSDINPCVGLG-------------RHAHFENFGMAFLTLFRIATGDNWNGIMKDTLREKCISSEDCQRNCCVSAIIAPIYFVIFXXXXXXXXXXXXXXXXXKHLEESHKMMCDDYELEREVQRDLDEEAKELAREKQLKDEENNENTLI 5730 L+W +R I V +F I I +N ++M E+H P++L L+ N FFT+ F LE LLK++A GL Y++D +N D IV LS+ + + + V+R R+ R+LKL++ +R L +++ + V L L +IF+ LG+ LFG C+ +P GL +F+NF A +T+F+I T ++WN ++ + + + + A +YFV + +VL N++VA+L++ +ES + E +R L+E+A++ A E++ DE E LI Sbjct: 639 LWW-----FREKIQKFVICDHFTRGILVAILVNTLSMGVEYHQQPEILTVILEYSNLFFTALFALEMLLKIIASGLFGYLADGFNLFDGGIVALSVLELFQE---------GKGGLSVLRTFRLLRILKLVRFMPALRYQLVVMLRTMDNVTVFFGLLVLFIFIFSTLGMVLFGCKFCN--HPDTGLQCTSAQVISSICECDRMNFDNFLFATVTVFQILTQEDWNMVLFNGMAQ--------------TNPWAALYFVALMTFGNYVLFNLLVAILVEGFQES----------KEEEKRQLEEDARKQAVEEE--DERKRELELI 922 HSP 7 Score: 68.5514 bits (166), Expect = 7.162e-11 Identity = 54/211 (25.59%), Postives = 99/211 (46.92%), Query Frame = 1 Query: 2164 IKTLVNDVKFQRGILIAILINTLSMGIEYHQQPVQLTQTLEFSNIVFSILFLIEMILKLIGEGILGYIKNGFNLFDGIIVVLGVIELCQQG--------GTSGLSILRTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKFCTIENNKRTCD----RKNFDSLLWSIVTVFQILTQEDWNTVLYNGM 2760 + +V F I I IN +SM +E++ P+ L L+ N F+ +F +E +KLI G + +N D IV+L + + + + + ++R R+ R+LKL++ +R L + + V +L L FIF+ LG+ LFG C+ CD +F + + +T+F+I T ++WN ++ + + Sbjct: 1441 LHGIVTSKYFDLAIAAVIGINVISMAMEFYMMPMGLKYVLKALNYFFTAVFTLEAAMKLIALGFKRFFIEKWNRLDMFIVILSIAGIIFEEFEALELPINPTIIRVMRVLRIARVLKLLKMAKGIRSLLDTVGEALPQVGNLGSLFFLLFFIFAALGVELFGKLECS---EDHPCDGLGEHAHFKNFGMAFLTLFRIATGDNWNGIMKDAL 1648 HSP 8 Score: 67.3958 bits (163), Expect = 1.313e-10 Identity = 69/278 (24.82%), Postives = 129/278 (46.40%), Query Frame = 1 Query: 2161 KIKTLVNDVK--FQRGILIAILINTLSMGIEYHQQPVQL--TQTLEFSNIVFSILFLIEMILKLIGEGIL----GYIKNGFNLFDGIIVVLGVIELCQQGGTSGLSILRTFRLL---------RILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFG---------------CKFCTIEN--NKRTCDRKNFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTS----------SWAALYFIALMTFGNYVLFNLLVAILVEGF 2862 +IK L K F +L I IN +++ +E P Q L S +F+++F EM++K+I G Y K+G+N+ DGI+VV+ +I + + +G S + F ++ R L+++ P ++ + +I ++ + + F IF ILG+ LF K IE+ NK R NFD+L +++++F + +++ W +++Y G+ W +YFI+ + + + N+ V ++VE F Sbjct: 1108 RIKCLQTTQKKWFDYTVLFFIGINCITLAMERPSIPPDSFERQFLHISGYIFTVIFTGEMMMKVIANGCFIGQAAYFKDGWNILDGILVVISLINIAFELLATGDSP-KIFGVIRVLRLLRALRPLRVINRAPGVKLVVMTLISSLKPIGNIVLICCTFFIIFGILGVQLFKGMMYHCIGPEVGNVTTKADCIEDYRNKWVNHRYNFDNLGQALMSLFVLSSKDGWVSIMYQGIDAVGVDVQPIENYNEWRMIYFISFLLLVGFFVLNMFVGVVVENF 1384 HSP 9 Score: 65.4698 bits (158), Expect = 5.819e-10 Identity = 44/122 (36.07%), Postives = 66/122 (54.10%), Query Frame = 1 Query: 331 TVFHIFHQN-KHP-RDWCLKIITWPWFEQLSMTIIAVNCITLSMYQPCGDQNCETSKCQIMQAFDYIIFAFFTCEMVIKIIAMG-FLGDLGYFGDTWNRLDMFIVIVGSIEI---LPSTGNN 678 T F +F K+P R CL+ WF+ + I +NCITL+M +P ++ + Q + YI FT EM++K+IA G F+G YF D WN LD +V++ I I L +TG++ Sbjct: 1094 TEFSLFLMGPKNPLRIKCLQTTQKKWFDYTVLFFIGINCITLAMERPSIPP--DSFERQFLHISGYIFTVIFTGEMMMKVIANGCFIGQAAYFKDGWNILDGILVVISLINIAFELLATGDS 1213 HSP 10 Score: 64.3142 bits (155), Expect = 1.131e-9 Identity = 44/136 (32.35%), Postives = 69/136 (50.74%), Query Frame = 1 Query: 346 FHQNKHPRDWCLKIITWPWFEQLSMTIIAVNCITLSM---YQPCGDQNCETSKCQIMQAFDYIIFAFFTCEMVIKIIAMGFLGDLGYFGDTWNRLDMFIVIVGSIEILPSTGNNIGL----TAIRTIRVLRPLRAI 732 +H H R + I+T +F+ +I +N I+++M P G + +++A +Y A FT E +K+IA+GF +F + WNRLDMFIVI+ I+ + L T IR +RVLR R + Sbjct: 1431 YHDYGHTRLFLHGIVTSKYFDLAIAAVIGINVISMAMEFYMMPMGLK-------YVLKALNYFFTAVFTLEAAMKLIALGFKR---FFIEKWNRLDMFIVILSIAGIIFEEFEALELPINPTIIRVMRVLRIARVL 1556 HSP 11 Score: 57.7658 bits (138), Expect = 1.081e-7 Identity = 25/81 (30.86%), Postives = 47/81 (58.02%), Query Frame = 1 Query: 1192 INFDNIGFAWVAIFQVISMESWVDIMYYVQDAHSFWDWIYFVALIIIGSFFMINLCLVVIASQFSETKRRETERMWIERRR 1434 +NFDN FA V +FQ+++ E W +++ + W +YFVAL+ G++ + NL + ++ F E+K E ++ + R+ Sbjct: 826 MNFDNFLFATVTVFQILTQEDWNMVLFNGMAQTNPWAALYFVALMTFGNYVLFNLLVAILVEGFQESKEEEKRQLEEDARK 906 HSP 12 Score: 54.299 bits (129), Expect = 1.260e-6 Identity = 29/96 (30.21%), Postives = 53/96 (55.21%), Query Frame = 1 Query: 4426 NDCLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFHKCQENQ 4713 N+C +N ++ +FDN+G A +A+F++ S +GW IMY DA H+ W IYF+ +++ AFF++N+ + V+ F + + + Sbjct: 377 NECQVMQRNPFQGS-VSFDNIGFAWVAIFLVISLEGWTDIMYYVQDA----------HSFWNWIYFVLLIVIGAFFMINLCLVVIATQFAETKRRE 461
BLAST of Voltage-dependent T-type calcium channel subunit alpha vs. Ensembl Celegans
Match: cca-1 (Voltage-dependent T-type calcium channel subunit alpha [Source:UniProtKB/TrEMBL;Acc:A0A0K3ASP4]) HSP 1 Score: 701.434 bits (1809), Expect = 0.000e+0 Identity = 421/694 (60.66%), Postives = 506/694 (72.91%), Query Frame = 1 Query: 3664 AREKALEEPDD-----SNSESQNSSRMNNVEDPDEEDMEAMICLSKCCPQPKGIFAKRYYHSLYVFSVDNQFRQKCQHIVDKKSFDYLVLFFITLNCITLAMERPSIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILL-GHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKFYYCDGPHLQAVKTKNDCLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFHKCQE-----------NQXXXXXXXXXXXXXXXXXXXXXHLRAPLYWENYSKWRRTINSVVTSKYFDLAIAGVIGLNVITMATEFHMMPQVLKTALKVFNYFFTSTFVXXXXXXXXXXXXXRYISDKWNQLDMMIVILSIAGVVIDEVESNFMPINPTIMRVMRVLRIARVLKLLKMASGIRALLDTVIQALPQVGNXXXXXXXXXXXXXXXXVELFGRLECSDINPCVGLGRHAHFENFGMAFLTLFRIATGDNWNGIMKDTLREKCISSEDCQRNCCVSAIIAPIYFVIFXXXXXXXXXXXXXXXXXKHLEESHKMMCD------DYELEREVQRDLDEEAKE 5676 AREK LE + + E +N ++ N L K C R SL++ N R KC KK FDY VLFFI +NCITLAMERPSIPP S ER FL ++ YIFT+IFTGEM++KV++ G IG AY K GWNI+DG LV ISL+++ +L G S +IFG++RV RLLR LRPLRVI+RAPG+KLVV TL+SSL+PIGNIVLICCTFFIIFGILGVQLFKG Y+C GP + V TK DC++ +N+W N +YNFDNLGQALM+LFVLSSKDGWV IMY GIDAVGV++QP EN+NEW +IYFISFLLLV FFVLNMFVGVVVENFHKC+E + + K +R K++K R Y+ +Y R ++ +VTSKYFDLAIA VIG+NVI+MA EF+MMP LK LK NYFFT+ F LEA +KL+ALG R+ +KWN+LDM IVILSIAG++ +E E+ +PINPTI+RVMRVLRIARVLKLLKMA GIR+LLDTV +ALPQVGNLG LFFLLF+IFAALGVELFG+LECS+ +PC GLG HAHF+NFGMAFLTLFRIATGDNWNGIMKD LR+ C SS+ C+ NCCV I+AP +FVIFVL++QFVLVNVVVAVLMKHLEES+K + +E E+ + D+E E Sbjct: 1044 AREKFLEASQELKQALAEEEKRNEAKQNTF---------VRKLLKKTC------LHNRTEFSLFLMGPKNPLRIKCLQTTQKKWFDYTVLFFIGINCITLAMERPSIPPDSFERQFLHISGYIFTVIFTGEMMMKVIANGCFIGQAAYFKDGWNILDGILVVISLINIAFELLATGDSPKIFGVIRVLRLLRALRPLRVINRAPGVKLVVMTLISSLKPIGNIVLICCTFFIIFGILGVQLFKGMMYHCIGPEVGNVTTKADCIEDYRNKWVNHRYNFDNLGQALMSLFVLSSKDGWVSIMYQGIDAVGVDVQPIENYNEWRMIYFISFLLLVGFFVLNMFVGVVVENFHKCKEALEKEMREKEKEKRLKRKLKRQKFEESMAGKRKKMERNYPYYHDYGHTRLFLHGIVTSKYFDLAIAAVIGINVISMAMEFYMMPMGLKYVLKALNYFFTAVFTLEAAMKLIALGFKRFFIEKWNRLDMFIVILSIAGIIFEEFEALELPINPTIIRVMRVLRIARVLKLLKMAKGIRSLLDTVGEALPQVGNLGSLFFLLFFIFAALGVELFGKLECSEDHPCDGLGEHAHFKNFGMAFLTLFRIATGDNWNGIMKDALRDDCDSSDHCETNCCVDPILAPCFFVIFVLISQFVLVNVVVAVLMKHLEESNKRDAEGPAEPTGENIENEITKSDDDEIVE 1722 HSP 2 Score: 375.941 bits (964), Expect = 3.372e-105 Identity = 217/406 (53.45%), Postives = 281/406 (69.21%), Query Frame = 1 Query: 307 LIYHGFYATVFHIFHQNKHPRDWCLKIITWPWFEQLSMTIIAVNCITLSMYQPCGDQ-NCETSKCQIMQAFDYIIFAFFTCEMVIKIIAMGFLGDLGYFGDTWNRLDMFIVIVGSIEIL--PSTGNNIGLTAIRTIRVLRPLRAINRIPSMRIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQMWQGVLRNRCYLNLNESFRHPGLNLSSFYQINRTLFLNAVDKDFICSTDKNNGILKCSDIPPSIMLLSNNSLQICKQPARPFTDNLPTKHSCVNWNQYYTDCQPGEKNPYEGAINFDNIGFAWVAIFQVISMESWVDIMYYVQDAHSFWDWIYFVALIIIGSFFMINLCLVVIASQFSETKRRETERMWIERRRF---NSSNCS------SISKDEPQTCY 1488 L Y GF F+Q + PR W L+++ PWF++++M +I +NC+TL MY+PC D +C+T +CQI+ D IF +F EMVIKI+A+GF G Y DTWNRLD FIV+ G E + G NI LTAIRT+RVLRPLRA+NRIPSMRILV LLLDTLPMLGNVLLLCFFVFFIFGI+GVQ+W G+LRNRC +NL ++ L + ++ R ++ICS NG+ CS++PP + +L + + + T SC+NWN YY +CQ ++NP++G+++FDNIGFAWVAIF VIS+E W DIMYYVQDAHSFW+WIYFV LI+IG+FFMINLCLVVIA+QF+ETKRRETERM ER+ +S +C+ + SK+E T Y Sbjct: 100 LPYPGFAEPALRCFYQARPPRKWALQMVMSPWFDRITMAVIMINCVTLGMYRPCEDGPDCDTYRCQILDIIDNCIFVYFAFEMVIKIMALGFYGPAAYMSDTWNRLDFFIVMAGIAEFVLHEYLGGNINLTAIRTVRVLRPLRAVNRIPSMRILVNLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAGLLRNRCVINLPKTISENQSALFNNVKLTRFYIPEDTSLEYICSQPDANGLHTCSNLPPYTVDGVKCNLTLDEY-------DKVTNDSCINWNIYYNECQVMQRNPFQGSVSFDNIGFAWVAIFLVISLEGWTDIMYYVQDAHSFWNWIYFVLLIVIGAFFMINLCLVVIATQFAETKRRETERMLQERKMLLNRDSISCTGSEIGGASSKEEGDTVY 498 HSP 3 Score: 315.464 bits (807), Expect = 2.176e-86 Identity = 169/274 (61.68%), Postives = 215/274 (78.47%), Query Frame = 1 Query: 2155 QQKIKTLVNDVKFQRGILIAILINTLSMGIEYHQQPVQLTQTLEFSNIVFSILFLIEMILKLIGEGILGYIKNGFNLFDGIIVVLGVIELCQQGGTSGLSILRTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKFCTIENN-----KRTCDRKNFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTSSWAALYFIALMTFGNYVLFNLLVAILVEGFSSERLDEQKLLHN--YRQSLKKRRANNKQLRIM 2955 ++KI+ V F RGIL+AIL+NTLSMG+EYHQQP LT LE+SN+ F+ LF +EM+LK+I G+ GY+ +GFNLFDG IV L V+EL Q+G GLS+LRTFRLLRILKLVRFMPALR QL VM+RT+DNV FF LL+LFIFIFSILGM+LFGCKFC +E + C+RKNFD+LLW+++TVFQILTQEDWN VL+NGM +T+ WAALYF+ALMTFGNYVLFNLLVAILVEGF + +E++ L +Q++++ ++L ++ Sbjct: 643 REKIQKFVICDHFTRGILVAILVNTLSMGVEYHQQPEILTVILEYSNLFFTALFALEMLLKIIASGLFGYLADGFNLFDGGIVALSVLELFQEG-KGGLSVLRTFRLLRILKLVRFMPALRYQLVVMLRTMDNVTVFFGLLVLFIFIFSILGMNLFGCKFCKVEEKFLGGLAKKCERKNFDTLLWALITVFQILTQEDWNMVLFNGMAQTNPWAALYFVALMTFGNYVLFNLLVAILVEGFQESKEEEKRQLEEDARKQAVEEEDERKRELELI 915 HSP 4 Score: 111.694 bits (278), Expect = 4.638e-24 Identity = 79/284 (27.82%), Postives = 138/284 (48.59%), Query Frame = 1 Query: 3862 FRQKCQHIVDKKSFDYLVLFFITLNCITLAMERPSIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKFYYCDGPHLQAVKTKNDCLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFHKCQENQ 4713 FR+K Q V F +L I +N +++ +E P + L +N FT +F EM++K+++ GL YL G+N+ DG +V +S+L+LF G S +LR FRLLR L+ +R + P L+ + +L ++ + + F IF ILG+ LF KF + L + K C ++ NFD L AL+ +F + +++ W +++ G+ N WA +YF++ + + + N+ V ++VE F + +E + Sbjct: 642 FREKIQKFVICDHFTRGILVAILVNTLSMGVEYHQQP--EILTVILEYSNLFFTALFALEMLLKIIASGLF----GYLADGFNLFDGGIVALSVLELFQEGKGGLS-----VLRTFRLLRILKLVRFM---PALRYQLVVMLRTMDNVTVFFGLLVLFIFIFSILGMNLFGCKFCKVEEKFLGGLAKK--C----------ERKNFDTLLWALITVFQILTQEDWNMVLFNGM----------AQTNPWAALYFVALMTFGNYVLFNLLVAILVEGFQESKEEE 889 HSP 5 Score: 82.0333 bits (201), Expect = 5.771e-15 Identity = 61/175 (34.86%), Postives = 96/175 (54.86%), Query Frame = 1 Query: 3865 RQKCQHIVDKKSFDYLVLFFITLNCITLAMERP--SIPPHSKER--LFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKG 4377 R+ +V FD + + I +NC+TL M RP P R + + N IF + F EM+IK+++ G G AY+ WN +D F+V + + + LG + + I R +R LRPLR ++R P ++++V LL +L +GN++L+C F IFGI+GVQL+ G Sbjct: 120 RKWALQMVMSPWFDRITMAVIMINCVTLGMYRPCEDGPDCDTYRCQILDIIDNCIF-VYFAFEMVIKIMALGFY-GPAAYMSDTWNRLDFFIVMAGIAEFVLHEYLGGNINLTAI----RTVRVLRPLRAVNRIPSMRILVNLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAG 288 HSP 6 Score: 69.707 bits (169), Expect = 2.719e-11 Identity = 91/317 (28.71%), Postives = 155/317 (48.90%), Query Frame = 1 Query: 4792 LYWENYSKWRRTINSVVTSKYFDLAIAGVIGLNVITMATEFHMMPQVLKTALKVFNYFFTSTFVXXXXXXXXXXXXXRYISDKWNQLDMMIVILSIAGVVIDEVESNFMPINPTIMRVMRVLRIARVLKLLKMASGIRALLDTVIQALPQVGNXXXXXXXXXXXXXXXXVELFGRLECSDINPCV-GLGRHAHFENFGM---AFLTLFRIATGDNWNGIMKDTLREKCISSEDCQRNCCVSAIIAPIYFVIFXXXXXXXXXXXXXXXXXKHLEESHKMMCDDYELEREVQRDLDEEAKELAREKQLKDEENNENTLI 5730 L+W +R I V +F I I +N ++M E+H P++L L+ N FFT+ F LE LLK++A GL Y++D +N D IV LS+ + + + V+R R+ R+LKL++ +R L +++ + V L L +IF+ LG+ LFG C + GL + +NF A +T+F+I T ++WN ++ + + + + A +YFV + +VL N++VA+L++ +ES + E +R L+E+A++ A E++ DE E LI Sbjct: 639 LWW-----FREKIQKFVICDHFTRGILVAILVNTLSMGVEYHQQPEILTVILEYSNLFFTALFALEMLLKIIASGLFGYLADGFNLFDGGIVALSVLELFQE---------GKGGLSVLRTFRLLRILKLVRFMPALRYQLVVMLRTMDNVTVFFGLLVLFIFIFSILGMNLFGCKFCKVEEKFLGGLAKKCERKNFDTLLWALITVFQILTQEDWNMVLFNGMAQ--------------TNPWAALYFVALMTFGNYVLFNLLVAILVEGFQES----------KEEEKRQLEEDARKQAVEEE--DERKRELELI 915 HSP 7 Score: 68.1662 bits (165), Expect = 8.257e-11 Identity = 54/211 (25.59%), Postives = 99/211 (46.92%), Query Frame = 1 Query: 2164 IKTLVNDVKFQRGILIAILINTLSMGIEYHQQPVQLTQTLEFSNIVFSILFLIEMILKLIGEGILGYIKNGFNLFDGIIVVLGVIELCQQG--------GTSGLSILRTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKFCTIENNKRTCD----RKNFDSLLWSIVTVFQILTQEDWNTVLYNGM 2760 + +V F I I IN +SM +E++ P+ L L+ N F+ +F +E +KLI G + +N D IV+L + + + + + ++R R+ R+LKL++ +R L + + V +L L FIF+ LG+ LFG C+ CD +F + + +T+F+I T ++WN ++ + + Sbjct: 1434 LHGIVTSKYFDLAIAAVIGINVISMAMEFYMMPMGLKYVLKALNYFFTAVFTLEAAMKLIALGFKRFFIEKWNRLDMFIVILSIAGIIFEEFEALELPINPTIIRVMRVLRIARVLKLLKMAKGIRSLLDTVGEALPQVGNLGSLFFLLFFIFAALGVELFGKLECS---EDHPCDGLGEHAHFKNFGMAFLTLFRIATGDNWNGIMKDAL 1641 HSP 8 Score: 67.3958 bits (163), Expect = 1.539e-10 Identity = 69/278 (24.82%), Postives = 129/278 (46.40%), Query Frame = 1 Query: 2161 KIKTLVNDVK--FQRGILIAILINTLSMGIEYHQQPVQL--TQTLEFSNIVFSILFLIEMILKLIGEGIL----GYIKNGFNLFDGIIVVLGVIELCQQGGTSGLSILRTFRLL---------RILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFG---------------CKFCTIEN--NKRTCDRKNFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTS----------SWAALYFIALMTFGNYVLFNLLVAILVEGF 2862 +IK L K F +L I IN +++ +E P Q L S +F+++F EM++K+I G Y K+G+N+ DGI+VV+ +I + + +G S + F ++ R L+++ P ++ + +I ++ + + F IF ILG+ LF K IE+ NK R NFD+L +++++F + +++ W +++Y G+ W +YFI+ + + + N+ V ++VE F Sbjct: 1101 RIKCLQTTQKKWFDYTVLFFIGINCITLAMERPSIPPDSFERQFLHISGYIFTVIFTGEMMMKVIANGCFIGQAAYFKDGWNILDGILVVISLINIAFELLATGDSP-KIFGVIRVLRLLRALRPLRVINRAPGVKLVVMTLISSLKPIGNIVLICCTFFIIFGILGVQLFKGMMYHCIGPEVGNVTTKADCIEDYRNKWVNHRYNFDNLGQALMSLFVLSSKDGWVSIMYQGIDAVGVDVQPIENYNEWRMIYFISFLLLVGFFVLNMFVGVVVENF 1377 HSP 9 Score: 65.4698 bits (158), Expect = 5.576e-10 Identity = 44/122 (36.07%), Postives = 66/122 (54.10%), Query Frame = 1 Query: 331 TVFHIFHQN-KHP-RDWCLKIITWPWFEQLSMTIIAVNCITLSMYQPCGDQNCETSKCQIMQAFDYIIFAFFTCEMVIKIIAMG-FLGDLGYFGDTWNRLDMFIVIVGSIEI---LPSTGNN 678 T F +F K+P R CL+ WF+ + I +NCITL+M +P + + + Q + YI FT EM++K+IA G F+G YF D WN LD +V++ I I L +TG++ Sbjct: 1087 TEFSLFLMGPKNPLRIKCLQTTQKKWFDYTVLFFIGINCITLAMERPSIPPD--SFERQFLHISGYIFTVIFTGEMMMKVIANGCFIGQAAYFKDGWNILDGILVVISLINIAFELLATGDS 1206 HSP 10 Score: 64.3142 bits (155), Expect = 1.112e-9 Identity = 44/136 (32.35%), Postives = 69/136 (50.74%), Query Frame = 1 Query: 346 FHQNKHPRDWCLKIITWPWFEQLSMTIIAVNCITLSM---YQPCGDQNCETSKCQIMQAFDYIIFAFFTCEMVIKIIAMGFLGDLGYFGDTWNRLDMFIVIVGSIEILPSTGNNIGL----TAIRTIRVLRPLRAI 732 +H H R + I+T +F+ +I +N I+++M P G + +++A +Y A FT E +K+IA+GF +F + WNRLDMFIVI+ I+ + L T IR +RVLR R + Sbjct: 1424 YHDYGHTRLFLHGIVTSKYFDLAIAAVIGINVISMAMEFYMMPMGLK-------YVLKALNYFFTAVFTLEAAMKLIALGFKR---FFIEKWNRLDMFIVILSIAGIIFEEFEALELPINPTIIRVMRVLRIARVL 1549 HSP 11 Score: 54.299 bits (129), Expect = 1.441e-6 Identity = 29/96 (30.21%), Postives = 53/96 (55.21%), Query Frame = 1 Query: 4426 NDCLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFHKCQENQ 4713 N+C +N ++ +FDN+G A +A+F++ S +GW IMY DA H+ W IYF+ +++ AFF++N+ + V+ F + + + Sbjct: 377 NECQVMQRNPFQGS-VSFDNIGFAWVAIFLVISLEGWTDIMYYVQDA----------HSFWNWIYFVLLIVIGAFFMINLCLVVIATQFAETKRRE 461 HSP 12 Score: 53.5286 bits (127), Expect = 2.001e-6 Identity = 22/80 (27.50%), Postives = 46/80 (57.50%), Query Frame = 1 Query: 1195 NFDNIGFAWVAIFQVISMESWVDIMYYVQDAHSFWDWIYFVALIIIGSFFMINLCLVVIASQFSETKRRETERMWIERRR 1434 NFD + +A + +FQ+++ E W +++ + W +YFVAL+ G++ + NL + ++ F E+K E ++ + R+ Sbjct: 820 NFDTLLWALITVFQILTQEDWNMVLFNGMAQTNPWAALYFVALMTFGNYVLFNLLVAILVEGFQESKEEEKRQLEEDARK 899
BLAST of Voltage-dependent T-type calcium channel subunit alpha vs. Ensembl Celegans
Match: cca-1 (Voltage-dependent T-type calcium channel subunit alpha [Source:UniProtKB/TrEMBL;Acc:A0A0K3ASP4]) HSP 1 Score: 701.434 bits (1809), Expect = 0.000e+0 Identity = 421/694 (60.66%), Postives = 506/694 (72.91%), Query Frame = 1 Query: 3664 AREKALEEPDD-----SNSESQNSSRMNNVEDPDEEDMEAMICLSKCCPQPKGIFAKRYYHSLYVFSVDNQFRQKCQHIVDKKSFDYLVLFFITLNCITLAMERPSIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILL-GHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKFYYCDGPHLQAVKTKNDCLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFHKCQE-----------NQXXXXXXXXXXXXXXXXXXXXXHLRAPLYWENYSKWRRTINSVVTSKYFDLAIAGVIGLNVITMATEFHMMPQVLKTALKVFNYFFTSTFVXXXXXXXXXXXXXRYISDKWNQLDMMIVILSIAGVVIDEVESNFMPINPTIMRVMRVLRIARVLKLLKMASGIRALLDTVIQALPQVGNXXXXXXXXXXXXXXXXVELFGRLECSDINPCVGLGRHAHFENFGMAFLTLFRIATGDNWNGIMKDTLREKCISSEDCQRNCCVSAIIAPIYFVIFXXXXXXXXXXXXXXXXXKHLEESHKMMCD------DYELEREVQRDLDEEAKE 5676 AREK LE + + E +N ++ N L K C R SL++ N R KC KK FDY VLFFI +NCITLAMERPSIPP S ER FL ++ YIFT+IFTGEM++KV++ G IG AY K GWNI+DG LV ISL+++ +L G S +IFG++RV RLLR LRPLRVI+RAPG+KLVV TL+SSL+PIGNIVLICCTFFIIFGILGVQLFKG Y+C GP + V TK DC++ +N+W N +YNFDNLGQALM+LFVLSSKDGWV IMY GIDAVGV++QP EN+NEW +IYFISFLLLV FFVLNMFVGVVVENFHKC+E + + K +R K++K R Y+ +Y R ++ +VTSKYFDLAIA VIG+NVI+MA EF+MMP LK LK NYFFT+ F LEA +KL+ALG R+ +KWN+LDM IVILSIAG++ +E E+ +PINPTI+RVMRVLRIARVLKLLKMA GIR+LLDTV +ALPQVGNLG LFFLLF+IFAALGVELFG+LECS+ +PC GLG HAHF+NFGMAFLTLFRIATGDNWNGIMKD LR+ C SS+ C+ NCCV I+AP +FVIFVL++QFVLVNVVVAVLMKHLEES+K + +E E+ + D+E E Sbjct: 1044 AREKFLEASQELKQALAEEEKRNEAKQNTF---------VRKLLKKTC------LHNRTEFSLFLMGPKNPLRIKCLQTTQKKWFDYTVLFFIGINCITLAMERPSIPPDSFERQFLHISGYIFTVIFTGEMMMKVIANGCFIGQAAYFKDGWNILDGILVVISLINIAFELLATGDSPKIFGVIRVLRLLRALRPLRVINRAPGVKLVVMTLISSLKPIGNIVLICCTFFIIFGILGVQLFKGMMYHCIGPEVGNVTTKADCIEDYRNKWVNHRYNFDNLGQALMSLFVLSSKDGWVSIMYQGIDAVGVDVQPIENYNEWRMIYFISFLLLVGFFVLNMFVGVVVENFHKCKEALEKEMREKEKEKRLKRKLKRQKFEESMAGKRKKMERNYPYYHDYGHTRLFLHGIVTSKYFDLAIAAVIGINVISMAMEFYMMPMGLKYVLKALNYFFTAVFTLEAAMKLIALGFKRFFIEKWNRLDMFIVILSIAGIIFEEFEALELPINPTIIRVMRVLRIARVLKLLKMAKGIRSLLDTVGEALPQVGNLGSLFFLLFFIFAALGVELFGKLECSEDHPCDGLGEHAHFKNFGMAFLTLFRIATGDNWNGIMKDALRDDCDSSDHCETNCCVDPILAPCFFVIFVLISQFVLVNVVVAVLMKHLEESNKRDAEGPAEPTGENIENEITKSDDDEIVE 1722 HSP 2 Score: 375.941 bits (964), Expect = 3.372e-105 Identity = 217/406 (53.45%), Postives = 281/406 (69.21%), Query Frame = 1 Query: 307 LIYHGFYATVFHIFHQNKHPRDWCLKIITWPWFEQLSMTIIAVNCITLSMYQPCGDQ-NCETSKCQIMQAFDYIIFAFFTCEMVIKIIAMGFLGDLGYFGDTWNRLDMFIVIVGSIEIL--PSTGNNIGLTAIRTIRVLRPLRAINRIPSMRIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQMWQGVLRNRCYLNLNESFRHPGLNLSSFYQINRTLFLNAVDKDFICSTDKNNGILKCSDIPPSIMLLSNNSLQICKQPARPFTDNLPTKHSCVNWNQYYTDCQPGEKNPYEGAINFDNIGFAWVAIFQVISMESWVDIMYYVQDAHSFWDWIYFVALIIIGSFFMINLCLVVIASQFSETKRRETERMWIERRRF---NSSNCS------SISKDEPQTCY 1488 L Y GF F+Q + PR W L+++ PWF++++M +I +NC+TL MY+PC D +C+T +CQI+ D IF +F EMVIKI+A+GF G Y DTWNRLD FIV+ G E + G NI LTAIRT+RVLRPLRA+NRIPSMRILV LLLDTLPMLGNVLLLCFFVFFIFGI+GVQ+W G+LRNRC +NL ++ L + ++ R ++ICS NG+ CS++PP + +L + + + T SC+NWN YY +CQ ++NP++G+++FDNIGFAWVAIF VIS+E W DIMYYVQDAHSFW+WIYFV LI+IG+FFMINLCLVVIA+QF+ETKRRETERM ER+ +S +C+ + SK+E T Y Sbjct: 100 LPYPGFAEPALRCFYQARPPRKWALQMVMSPWFDRITMAVIMINCVTLGMYRPCEDGPDCDTYRCQILDIIDNCIFVYFAFEMVIKIMALGFYGPAAYMSDTWNRLDFFIVMAGIAEFVLHEYLGGNINLTAIRTVRVLRPLRAVNRIPSMRILVNLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAGLLRNRCVINLPKTISENQSALFNNVKLTRFYIPEDTSLEYICSQPDANGLHTCSNLPPYTVDGVKCNLTLDEY-------DKVTNDSCINWNIYYNECQVMQRNPFQGSVSFDNIGFAWVAIFLVISLEGWTDIMYYVQDAHSFWNWIYFVLLIVIGAFFMINLCLVVIATQFAETKRRETERMLQERKMLLNRDSISCTGSEIGGASSKEEGDTVY 498 HSP 3 Score: 315.464 bits (807), Expect = 2.176e-86 Identity = 169/274 (61.68%), Postives = 215/274 (78.47%), Query Frame = 1 Query: 2155 QQKIKTLVNDVKFQRGILIAILINTLSMGIEYHQQPVQLTQTLEFSNIVFSILFLIEMILKLIGEGILGYIKNGFNLFDGIIVVLGVIELCQQGGTSGLSILRTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKFCTIENN-----KRTCDRKNFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTSSWAALYFIALMTFGNYVLFNLLVAILVEGFSSERLDEQKLLHN--YRQSLKKRRANNKQLRIM 2955 ++KI+ V F RGIL+AIL+NTLSMG+EYHQQP LT LE+SN+ F+ LF +EM+LK+I G+ GY+ +GFNLFDG IV L V+EL Q+G GLS+LRTFRLLRILKLVRFMPALR QL VM+RT+DNV FF LL+LFIFIFSILGM+LFGCKFC +E + C+RKNFD+LLW+++TVFQILTQEDWN VL+NGM +T+ WAALYF+ALMTFGNYVLFNLLVAILVEGF + +E++ L +Q++++ ++L ++ Sbjct: 643 REKIQKFVICDHFTRGILVAILVNTLSMGVEYHQQPEILTVILEYSNLFFTALFALEMLLKIIASGLFGYLADGFNLFDGGIVALSVLELFQEG-KGGLSVLRTFRLLRILKLVRFMPALRYQLVVMLRTMDNVTVFFGLLVLFIFIFSILGMNLFGCKFCKVEEKFLGGLAKKCERKNFDTLLWALITVFQILTQEDWNMVLFNGMAQTNPWAALYFVALMTFGNYVLFNLLVAILVEGFQESKEEEKRQLEEDARKQAVEEEDERKRELELI 915 HSP 4 Score: 111.694 bits (278), Expect = 4.638e-24 Identity = 79/284 (27.82%), Postives = 138/284 (48.59%), Query Frame = 1 Query: 3862 FRQKCQHIVDKKSFDYLVLFFITLNCITLAMERPSIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKFYYCDGPHLQAVKTKNDCLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFHKCQENQ 4713 FR+K Q V F +L I +N +++ +E P + L +N FT +F EM++K+++ GL YL G+N+ DG +V +S+L+LF G S +LR FRLLR L+ +R + P L+ + +L ++ + + F IF ILG+ LF KF + L + K C ++ NFD L AL+ +F + +++ W +++ G+ N WA +YF++ + + + N+ V ++VE F + +E + Sbjct: 642 FREKIQKFVICDHFTRGILVAILVNTLSMGVEYHQQP--EILTVILEYSNLFFTALFALEMLLKIIASGLF----GYLADGFNLFDGGIVALSVLELFQEGKGGLS-----VLRTFRLLRILKLVRFM---PALRYQLVVMLRTMDNVTVFFGLLVLFIFIFSILGMNLFGCKFCKVEEKFLGGLAKK--C----------ERKNFDTLLWALITVFQILTQEDWNMVLFNGM----------AQTNPWAALYFVALMTFGNYVLFNLLVAILVEGFQESKEEE 889 HSP 5 Score: 82.0333 bits (201), Expect = 5.771e-15 Identity = 61/175 (34.86%), Postives = 96/175 (54.86%), Query Frame = 1 Query: 3865 RQKCQHIVDKKSFDYLVLFFITLNCITLAMERP--SIPPHSKER--LFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKG 4377 R+ +V FD + + I +NC+TL M RP P R + + N IF + F EM+IK+++ G G AY+ WN +D F+V + + + LG + + I R +R LRPLR ++R P ++++V LL +L +GN++L+C F IFGI+GVQL+ G Sbjct: 120 RKWALQMVMSPWFDRITMAVIMINCVTLGMYRPCEDGPDCDTYRCQILDIIDNCIF-VYFAFEMVIKIMALGFY-GPAAYMSDTWNRLDFFIVMAGIAEFVLHEYLGGNINLTAI----RTVRVLRPLRAVNRIPSMRILVNLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAG 288 HSP 6 Score: 69.707 bits (169), Expect = 2.719e-11 Identity = 91/317 (28.71%), Postives = 155/317 (48.90%), Query Frame = 1 Query: 4792 LYWENYSKWRRTINSVVTSKYFDLAIAGVIGLNVITMATEFHMMPQVLKTALKVFNYFFTSTFVXXXXXXXXXXXXXRYISDKWNQLDMMIVILSIAGVVIDEVESNFMPINPTIMRVMRVLRIARVLKLLKMASGIRALLDTVIQALPQVGNXXXXXXXXXXXXXXXXVELFGRLECSDINPCV-GLGRHAHFENFGM---AFLTLFRIATGDNWNGIMKDTLREKCISSEDCQRNCCVSAIIAPIYFVIFXXXXXXXXXXXXXXXXXKHLEESHKMMCDDYELEREVQRDLDEEAKELAREKQLKDEENNENTLI 5730 L+W +R I V +F I I +N ++M E+H P++L L+ N FFT+ F LE LLK++A GL Y++D +N D IV LS+ + + + V+R R+ R+LKL++ +R L +++ + V L L +IF+ LG+ LFG C + GL + +NF A +T+F+I T ++WN ++ + + + + A +YFV + +VL N++VA+L++ +ES + E +R L+E+A++ A E++ DE E LI Sbjct: 639 LWW-----FREKIQKFVICDHFTRGILVAILVNTLSMGVEYHQQPEILTVILEYSNLFFTALFALEMLLKIIASGLFGYLADGFNLFDGGIVALSVLELFQE---------GKGGLSVLRTFRLLRILKLVRFMPALRYQLVVMLRTMDNVTVFFGLLVLFIFIFSILGMNLFGCKFCKVEEKFLGGLAKKCERKNFDTLLWALITVFQILTQEDWNMVLFNGMAQ--------------TNPWAALYFVALMTFGNYVLFNLLVAILVEGFQES----------KEEEKRQLEEDARKQAVEEE--DERKRELELI 915 HSP 7 Score: 68.1662 bits (165), Expect = 8.257e-11 Identity = 54/211 (25.59%), Postives = 99/211 (46.92%), Query Frame = 1 Query: 2164 IKTLVNDVKFQRGILIAILINTLSMGIEYHQQPVQLTQTLEFSNIVFSILFLIEMILKLIGEGILGYIKNGFNLFDGIIVVLGVIELCQQG--------GTSGLSILRTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKFCTIENNKRTCD----RKNFDSLLWSIVTVFQILTQEDWNTVLYNGM 2760 + +V F I I IN +SM +E++ P+ L L+ N F+ +F +E +KLI G + +N D IV+L + + + + + ++R R+ R+LKL++ +R L + + V +L L FIF+ LG+ LFG C+ CD +F + + +T+F+I T ++WN ++ + + Sbjct: 1434 LHGIVTSKYFDLAIAAVIGINVISMAMEFYMMPMGLKYVLKALNYFFTAVFTLEAAMKLIALGFKRFFIEKWNRLDMFIVILSIAGIIFEEFEALELPINPTIIRVMRVLRIARVLKLLKMAKGIRSLLDTVGEALPQVGNLGSLFFLLFFIFAALGVELFGKLECS---EDHPCDGLGEHAHFKNFGMAFLTLFRIATGDNWNGIMKDAL 1641 HSP 8 Score: 67.3958 bits (163), Expect = 1.539e-10 Identity = 69/278 (24.82%), Postives = 129/278 (46.40%), Query Frame = 1 Query: 2161 KIKTLVNDVK--FQRGILIAILINTLSMGIEYHQQPVQL--TQTLEFSNIVFSILFLIEMILKLIGEGIL----GYIKNGFNLFDGIIVVLGVIELCQQGGTSGLSILRTFRLL---------RILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFG---------------CKFCTIEN--NKRTCDRKNFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTS----------SWAALYFIALMTFGNYVLFNLLVAILVEGF 2862 +IK L K F +L I IN +++ +E P Q L S +F+++F EM++K+I G Y K+G+N+ DGI+VV+ +I + + +G S + F ++ R L+++ P ++ + +I ++ + + F IF ILG+ LF K IE+ NK R NFD+L +++++F + +++ W +++Y G+ W +YFI+ + + + N+ V ++VE F Sbjct: 1101 RIKCLQTTQKKWFDYTVLFFIGINCITLAMERPSIPPDSFERQFLHISGYIFTVIFTGEMMMKVIANGCFIGQAAYFKDGWNILDGILVVISLINIAFELLATGDSP-KIFGVIRVLRLLRALRPLRVINRAPGVKLVVMTLISSLKPIGNIVLICCTFFIIFGILGVQLFKGMMYHCIGPEVGNVTTKADCIEDYRNKWVNHRYNFDNLGQALMSLFVLSSKDGWVSIMYQGIDAVGVDVQPIENYNEWRMIYFISFLLLVGFFVLNMFVGVVVENF 1377 HSP 9 Score: 65.4698 bits (158), Expect = 5.576e-10 Identity = 44/122 (36.07%), Postives = 66/122 (54.10%), Query Frame = 1 Query: 331 TVFHIFHQN-KHP-RDWCLKIITWPWFEQLSMTIIAVNCITLSMYQPCGDQNCETSKCQIMQAFDYIIFAFFTCEMVIKIIAMG-FLGDLGYFGDTWNRLDMFIVIVGSIEI---LPSTGNN 678 T F +F K+P R CL+ WF+ + I +NCITL+M +P + + + Q + YI FT EM++K+IA G F+G YF D WN LD +V++ I I L +TG++ Sbjct: 1087 TEFSLFLMGPKNPLRIKCLQTTQKKWFDYTVLFFIGINCITLAMERPSIPPD--SFERQFLHISGYIFTVIFTGEMMMKVIANGCFIGQAAYFKDGWNILDGILVVISLINIAFELLATGDS 1206 HSP 10 Score: 64.3142 bits (155), Expect = 1.112e-9 Identity = 44/136 (32.35%), Postives = 69/136 (50.74%), Query Frame = 1 Query: 346 FHQNKHPRDWCLKIITWPWFEQLSMTIIAVNCITLSM---YQPCGDQNCETSKCQIMQAFDYIIFAFFTCEMVIKIIAMGFLGDLGYFGDTWNRLDMFIVIVGSIEILPSTGNNIGL----TAIRTIRVLRPLRAI 732 +H H R + I+T +F+ +I +N I+++M P G + +++A +Y A FT E +K+IA+GF +F + WNRLDMFIVI+ I+ + L T IR +RVLR R + Sbjct: 1424 YHDYGHTRLFLHGIVTSKYFDLAIAAVIGINVISMAMEFYMMPMGLK-------YVLKALNYFFTAVFTLEAAMKLIALGFKR---FFIEKWNRLDMFIVILSIAGIIFEEFEALELPINPTIIRVMRVLRIARVL 1549 HSP 11 Score: 54.299 bits (129), Expect = 1.441e-6 Identity = 29/96 (30.21%), Postives = 53/96 (55.21%), Query Frame = 1 Query: 4426 NDCLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFHKCQENQ 4713 N+C +N ++ +FDN+G A +A+F++ S +GW IMY DA H+ W IYF+ +++ AFF++N+ + V+ F + + + Sbjct: 377 NECQVMQRNPFQGS-VSFDNIGFAWVAIFLVISLEGWTDIMYYVQDA----------HSFWNWIYFVLLIVIGAFFMINLCLVVIATQFAETKRRE 461 HSP 12 Score: 53.5286 bits (127), Expect = 2.001e-6 Identity = 22/80 (27.50%), Postives = 46/80 (57.50%), Query Frame = 1 Query: 1195 NFDNIGFAWVAIFQVISMESWVDIMYYVQDAHSFWDWIYFVALIIIGSFFMINLCLVVIASQFSETKRRETERMWIERRR 1434 NFD + +A + +FQ+++ E W +++ + W +YFVAL+ G++ + NL + ++ F E+K E ++ + R+ Sbjct: 820 NFDTLLWALITVFQILTQEDWNMVLFNGMAQTNPWAALYFVALMTFGNYVLFNLLVAILVEGFQESKEEEKRQLEEDARK 899
BLAST of Voltage-dependent T-type calcium channel subunit alpha vs. Ensembl Fly
Match: Ca-alpha1T (gene:FBgn0264386 transcript:FBtr0304609) HSP 1 Score: 784.637 bits (2025), Expect = 0.000e+0 Identity = 446/636 (70.13%), Postives = 534/636 (83.96%), Query Frame = 1 Query: 3799 PKGIFAKRYYHSLYVFSVDNQFRQKCQHIVDKKSFDYLVLFFITLNCITLAMERPSIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKFYYCDGPHLQAVKTKNDCLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFHKCQENQXXXXXXXXXXXXXXXXXXXXXHLRAPLYWENYSKWRRTINSVVTSKYFDLAIAGVIGLNVITMATEFHMMPQVLKTALKVFNYFFTSTFVXXXXXXXXXXXXXRYISDKWNQLDMMIVILSIAGVVIDEVESN---FMPINPTIMRVMRVLRIARVLKLLKMASGIRALLDTVIQALPQVGNXXXXXXXXXXXXXXXXVELFGRLECSDINPCVGLGRHAHFENFGMAFLTLFRIATGDNWNGIMKDTLREKCISSEDCQRNCCVSAIIAPIYFVIFXXXXXXXXXXXXXXXXXKHLEESHKMMCDDYELEREVQRDLDEEAKELAREKQL 5697 PK +R +SLY+F DN+FRQ C V++K FD +VL FI LNCITLAMERP+IPP S ERLFL NY+FT++FT EM IKV++ G+ G AY SGWNIMDG LV IS++DL ++++ S RIFGILRVFRLLR+LRPLRVI+RAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKG FYYC+G +++ V+ ++C + N W N+KYNFD+LG+ALM+LFVLSS+DGWV IMYTG+DAVGV+ QP N+NEW L+YFI+F+LLV FFVLNMFVGVVVENFH+C+E QEKEEK RRAAKRA ++EKKR+ + P Y+ NYS R +++VVTSKYFDLAIA VIGLNV+TMA E++ MP LK ALK+FNYFFT+ F+LEA +KLVALG Y+ D+WNQLD+ IV+LSI G+V++E+E+N +PINPTI+RVMRVLRIARVLKLLKMA+GIRALLDTV+QALPQVGNLGLLFFLLF+IFAALGVELFGRLECSD PC GLG HAHF NFGMAFLTLFR+ATGDNWNGIMKDTLR+ C + DC RNCCVS++IAPI+FVIFVLMAQFVLVNVVVAVLMKHLEESHK M D+ ++E E++R+L E +E A+E++L Sbjct: 2105 PKHFTTEREDYSLYIFPEDNRFRQICTWFVNQKWFDNVVLLFIALNCITLAMERPNIPPSSTERLFLATANYVFTVVFTVEMFIKVVATGMFYGHDAYFTSGWNIMDGSLVTISIIDLLMSLISESSPRIFGILRVFRLLRSLRPLRVINRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGTFYYCEGENIKGVRNADECRRIPGNVWTNRKYNFDDLGKALMSLFVLSSRDGWVNIMYTGLDAVGVDQQPIVNYNEWRLLYFIAFILLVGFFVLNMFVGVVVENFHRCREEQEKEEKIRRAAKRALQMEKKRRRMHEPPYYTNYSPTRMFVHNVVTSKYFDLAIAAVIGLNVVTMAMEYYKMPSGLKYALKIFNYFFTAVFILEANMKLVALGWKLYLKDRWNQLDVGIVLLSIVGIVLEELETNTHQIIPINPTIIRVMRVLRIARVLKLLKMANGIRALLDTVMQALPQVGNLGLLFFLLFFIFAALGVELFGRLECSDEIPCQGLGEHAHFANFGMAFLTLFRVATGDNWNGIMKDTLRDNCDDAADCVRNCCVSSVIAPIFFVIFVLMAQFVLVNVVVAVLMKHLEESHKQMEDELDMEVELERELVRE-QEFAQEQKL 2739 HSP 2 Score: 417.157 bits (1071), Expect = 3.580e-117 Identity = 249/435 (57.24%), Postives = 308/435 (70.80%), Query Frame = 1 Query: 295 PNESLIYHGFYATVFHIFHQNKHPRDWCLKIITWPWFEQLSMTIIAVNCITLSMYQPCGDQNCETSKCQIMQAFDYIIFAFFTCEMVIKIIAMGFLGDLGYFGDTWNRLDMFIVIVGSIEILPSTGNNIGLTAIRTIRVLRPLRAINRIPSMRIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQMWQGVLRNRCYLNLNESFRHPGLNLSSFYQINRTLFLNAVDKDFICSTDKNNGILKCSDIPPSIMLLSNNSLQICKQPARPFTDNLPTKHSCVNWNQYYTDCQPGEKNPYEGAINFDNIGFAWVAIFQVISMESWVDIMYYVQDAHSFWDWIYFVALIIIGSFFMINLCLVVIASQFSETKRRETERMWIERRRFNSSNCSSISKD--EPQTCYLEXXXXXXXXXXXXYRRIVKLYNQIQIRHSKTAQG 1593 PN L Y GF Q PR+WCL +IT PWFE++S+ +I +NCITL MYQPC D C T++C+I+Q FD IIFAFF EM IK++AMG G Y D+WNRLD FIV+ G +E + N+ LTAIRTIRVLRPLRAINRIPSMRILVMLLLDTLPMLGNVLLLCFFVFFIFGIIGVQ+W+G+LR RC L E +P L LS +Y+ ++ D+D+ICST ++G+ C + PP + SL +C + A+ F N PT SCVNWNQYYT C+ +NP++G I+FDNIG AWVAIF VIS+E W DIMYYVQDAHSFWDWIYFV LI+IGSFFMINLCLVVIA+QFSETK+RE ERM ER R+ S++ + S + EP TCY EI+K I + + RR++K Y + + + +G Sbjct: 269 PN--LPYPGFPEISIRALTQYTRPRNWCLMLITNPWFERVSILVILLNCITLGMYQPCVDDACVTNRCKILQIFDDIIFAFFALEMTIKMVAMGICGKNTYLADSWNRLDFFIVLAGLLEYVMHV-ENLNLTAIRTIRVLRPLRAINRIPSMRILVMLLLDTLPMLGNVLLLCFFVFFIFGIIGVQLWEGILRQRCSLMRTEGMVYP-LTLSQYYEFSK-------DQDYICSTPNDSGMHLCGNFPPYRI----GSL-VCNEEAKLFDFNEPTNTSCVNWNQYYTTCKQSGENPFQGTISFDNIGMAWVAIFLVISLEGWTDIMYYVQDAHSFWDWIYFVLLIVIGSFFMINLCLVVIATQFSETKKREMERMRQERARYTSTSTLASSTNNSEPATCYAEIVKYIAHLWRRFKRRMLKKYRLYKYQRQQRKEG 687 HSP 3 Score: 322.783 bits (826), Expect = 4.327e-88 Identity = 181/272 (66.54%), Postives = 212/272 (77.94%), Query Frame = 1 Query: 2164 IKTLVNDVKFQRGILIAILINTLSMGIEYHQQPVQLTQTLEFSNIVFSILFLIEMILKLIGEGILGYIKNGFNLFDGIIVVLGVIELCQ-------QGGTSGLSILRTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKFCTIENNKRTCDRKNFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTSSWAALYFIALMTFGNYVLFNLLVAILVEGFSS--------------ERLDEQKLLHNYRQSL 2916 I+ LV FQ+GIL+AILINTLSMGIEYH QP +LT +E SN+VFS +F +EM+LK++ EG YI NGFN+FDGIIV+L IE+CQ GG SGLS+LRTFRLLRILKLVRFMP LR+QLFVM+RT+DNVA FF+LL+LFIFIFSILGM+LFGCKFC N + CDRKNFDSLLW++VTVFQILTQEDWN VL+NGM +TS WAALYF+ALMTFGNYVLFNLLVAILVEGFSS ++L E+ L NY + Sbjct: 1216 IRRLVEHKYFQQGILLAILINTLSMGIEYHNQPPELTAIVETSNVVFSGIFAVEMLLKVVAEGPFRYIANGFNVFDGIIVILSAIEICQTFMGNGTGGGGSGLSVLRTFRLLRILKLVRFMPNLRRQLFVMLRTMDNVAVFFSLLVLFIFIFSILGMNLFGCKFCEKVNGEMICDRKNFDSLLWALVTVFQILTQEDWNVVLFNGMEKTSHWAALYFVALMTFGNYVLFNLLVAILVEGFSSERNERREREQRELVKKLREETLAENYSDGM 1487 HSP 4 Score: 107.457 bits (267), Expect = 1.266e-22 Identity = 87/343 (25.36%), Postives = 159/343 (46.36%), Query Frame = 1 Query: 3706 ESQNSSRMNNVEDPDEEDMEAMIC--------LSKCCPQPKGIF-AKRYYHSLY--VFSVDNQFRQKCQHIVDKKSFDYLVLFFITLNCITLAMERPSIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDL---FITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKFYYCDGPHLQAVKTKNDCLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENF 4692 + Q +SRM P ME C LS +P+ R S+Y + V + R+ + +V+ K F +L I +N +++ +E + PP + +N +F+ IF EM++KV+++G Y+ +G+N+ DG +V +S +++ F+ G +LR FRLLR L+ +R + P L+ + +L ++ + + F IF ILG+ LF KF C K + E + NFD+L AL+ +F + +++ W +++ G+ E + WA +YF++ + + + N+ V ++VE F Sbjct: 1149 QGQGNSRMREPRAPTGNYMEDYACCYDLYQNALSPLDERPRQRSPTTRCLISVYRCMSRVCSWIRRYIRRLVEHKYFQQGILLAILINTLSMGIEYHNQPPELTA--IVETSNVVFSGIFAVEMLLKVVAEGPF----RYIANGFNVFDGIIVILSAIEICQTFMGNGTGGGGSGLSVLRTFRLLRILKLVRFM---PNLRRQLFVMLRTMDNVAVFFSLLVLFIFIFSILGMNLFGCKF----------------CEKVN-GEMICDRKNFDSLLWALVTVFQILTQEDWNVVLFNGM----------EKTSHWAALYFVALMTFGNYVLFNLLVAILVEGF 1455 HSP 5 Score: 82.0333 bits (201), Expect = 6.864e-15 Identity = 80/308 (25.97%), Postives = 139/308 (45.13%), Query Frame = 1 Query: 2173 LVNDVKFQRGILIAILINTLSMGIEYHQQPVQLTQTL--EFSNIVFSILFLIEMILKLIGEGIL----GYIKNGFNLFDGIIVVLGVIELCQQGGTSGLSILRTFRLLRILK---------LVRFMPALR---QQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKF--CTIEN-----NKRTCDR----------KNFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTS----------SWAALYFIALMTFGNYVLFNLLVAILVEGFSSERLDEQKLLHNYRQSLKKRRANNKQLRIMQH 2961 VN F +L+ I +N +++ +E P T+ L +N VF+++F +EM +K++ G+ Y +G+N+ DG +V + +I+L + S R F +LR+ + ++ P L+ Q L +R I N+ + F IF ILG+ LF F C EN N C R NFD L +++++F + +++ W ++Y G+ W LYFIA + + + N+ V ++VE F R +EQ+ R++ K+ K+ R M Sbjct: 2133 FVNQKWFDNVVLLFIALNCITLAMERPNIPPSSTERLFLATANYVFTVVFTVEMFIKVVATGMFYGHDAYFTSGWNIMDGSLVTISIIDLLMSLISE--SSPRIFGILRVFRLLRSLRPLRVINRAPGLKLVVQTLLSSLRPIGNIV---LICCTFFIIFGILGVQLFKGTFYYCEGENIKGVRNADECRRIPGNVWTNRKYNFDDLGKALMSLFVLSSRDGWVNIMYTGLDAVGVDQQPIVNYNEWRLLYFIAFILLVGFFVLNMFVGVVVENFHRCR-EEQEKEEKIRRAAKRALQMEKKRRRMHE 2434 HSP 6 Score: 81.2629 bits (199), Expect = 1.355e-14 Identity = 60/173 (34.68%), Postives = 93/173 (53.76%), Query Frame = 1 Query: 3865 RQKCQHIVDKKSFDYLVLFFITLNCITLAMERPSIPPH--SKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKG 4377 R C ++ F+ + + I LNCITL M +P + + L + + I F EM IK+++ G+ G YL WN +D F+V LL+ + H + L R +R LRPLR I+R P ++++V LL +L +GN++L+C F IFGI+GVQL++G Sbjct: 291 RNWCLMLITNPWFERVSILVILLNCITLGMYQPCVDDACVTNRCKILQIFDDIIFAFFALEMTIKMVAMGI-CGKNTYLADSWNRLDFFIVLAGLLEYVM-----HVENLN--LTAIRTIRVLRPLRAINRIPSMRILVMLLLDTLPMLGNVLLLCFFVFFIFGIIGVQLWEG 455 HSP 7 Score: 72.4034 bits (176), Expect = 5.446e-12 Identity = 52/207 (25.12%), Postives = 104/207 (50.24%), Query Frame = 1 Query: 2164 IKTLVNDVKFQRGILIAILINTLSMGIEYHQQPVQLTQTLEFSNIVFSILFLIEMILKLIGEGILGYIKNGFNLFDGIIVVLGVIELCQQGGTSG-----------LSILRTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKFCTIE-NNKRTCDRKNFDSLLWSIVTVFQILTQEDWNTVL 2748 + +V F I I +N ++M +EY++ P L L+ N F+ +F++E +KL+ G Y+K+ +N D IV+L ++ + + + + ++R R+ R+LKL++ +R L +++ + V L L FIF+ LG+ LFG C+ E + + +F + + +T+F++ T ++WN ++ Sbjct: 2448 VHNVVTSKYFDLAIAAVIGLNVVTMAMEYYKMPSGLKYALKIFNYFFTAVFILEANMKLVALGWKLYLKDRWNQLDVGIVLLSIVGIVLEELETNTHQIIPINPTIIRVMRVLRIARVLKLLKMANGIRALLDTVMQALPQVGNLGLLFFLLFFIFAALGVELFGRLECSDEIPCQGLGEHAHFANFGMAFLTLFRVATGDNWNGIM 2654 HSP 8 Score: 71.2478 bits (173), Expect = 1.209e-11 Identity = 68/211 (32.23%), Postives = 110/211 (52.13%), Query Frame = 1 Query: 4819 RRTINSVVTSKYFDLAIAGVIGLNVITMATEFHMMPQVLKTALKVFNYFFTSTFVXXXXXXXXXXXXXRYISDKWNQLDMMIVILSIAGVVIDEVESNFM----PINPTIMRVMRVLRIARVLKLLKMASGIRALLDTVIQALPQVGNXXXXXXXXXXXXXXXXVELFGRLECSDINPCVGLGRHAHFENFGMAFLTLFRIATGDNWNGIM 5439 RR I +V KYF I I +N ++M E+H P L ++ N F+ F +E LLK+VA G RYI++ +N D +IVILS E+ FM + + V+R R+ R+LKL++ +R L +++ + V L L +IF+ LG+ LFG C +N + R +F++ A +T+F+I T ++WN ++ Sbjct: 1213 RRYIRRLVEHKYFQQGILLAILINTLSMGIEYHNQPPELTAIVETSNVVFSGIFAVEMLLKVVAEGPFRYIANGFNVFDGIIVILSAI-----EICQTFMGNGTGGGGSGLSVLRTFRLLRILKLVRFMPNLRRQLFVMLRTMDNVAVFFSLLVLFIFIFSILGMNLFGCKFCEKVNGEMICDRK-NFDSLLWALVTVFQILTQEDWNVVL 1417 HSP 9 Score: 67.0106 bits (162), Expect = 2.247e-10 Identity = 46/152 (30.26%), Postives = 73/152 (48.03%), Query Frame = 1 Query: 337 FHIFHQNKHPRDWCLKIITWPWFEQLSMTIIAVNCITLSMYQPCGDQNCETSKCQ--IMQAFDYIIFAFFTCEMVIKIIAMG-FLGDLGYFGDTWNRLDMFIVIVGSIEILPSTGNNIGLTAIRTIRVLRPL---------RAINRIPSMRI 756 +IF ++ R C + WF+ + + IA+NCITL+M +P N S + + +Y+ FT EM IK++A G F G YF WN +D +V + I++L S I ++ R +LR R INR P +++ Sbjct: 2117 LYIFPEDNRFRQICTWFVNQKWFDNVVLLFIALNCITLAMERP----NIPPSSTERLFLATANYVFTVVFTVEMFIKVVATGMFYGHDAYFTSGWNIMDGSLVTISIIDLLMSL---ISESSPRIFGILRVFRLLRSLRPLRVINRAPGLKL 2261 HSP 10 Score: 55.8398 bits (133), Expect = 5.436e-7 Identity = 37/136 (27.21%), Postives = 75/136 (55.15%), Query Frame = 1 Query: 2173 LVNDVKFQRGILIAILINTLSMGIEYHQQP-------VQLTQTLE-FSNIVFSILFLIEMILKLIGEGILG---YIKNGFNLFDGIIVVLGVIELCQQGGTSGLSILRTFRLLRILKLVRFMPALRQQLFVMIRTI 2547 L+ + F+R ++ IL+N +++G+ QP + L+ F +I+F+ F +EM +K++ GI G Y+ + +N D IV+ G++E L+ +RT R+LR L+ + +P++R + +++ T+ Sbjct: 297 LITNPWFERVSILVILLNCITLGM---YQPCVDDACVTNRCKILQIFDDIIFA-FFALEMTIKMVAMGICGKNTYLADSWNRLDFFIVLAGLLEYVMHVENLNLTAIRTIRVLRPLRAINRIPSMRILVMLLLDTL 428 HSP 11 Score: 54.6842 bits (130), Expect = 1.313e-6 Identity = 27/94 (28.72%), Postives = 53/94 (56.38%), Query Frame = 1 Query: 4432 CLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFHKCQENQ 4713 C + +N ++ +FDN+G A +A+F++ S +GW IMY DA H+ W IYF+ +++ +FF++N+ + V+ F + ++ + Sbjct: 540 CKQSGENPFQG-TISFDNIGMAWVAIFLVISLEGWTDIMYYVQDA----------HSFWDWIYFVLLIVIGSFFMINLCLVVIATQFSETKKRE 622 HSP 12 Score: 54.6842 bits (130), Expect = 1.369e-6 Identity = 21/64 (32.81%), Postives = 40/64 (62.50%), Query Frame = 1 Query: 1195 NFDNIGFAWVAIFQVISMESWVDIMYYVQDAHSFWDWIYFVALIIIGSFFMINLCLVVIASQFS 1386 NFD++ +A V +FQ+++ E W +++ + S W +YFVAL+ G++ + NL + ++ FS Sbjct: 1393 NFDSLLWALVTVFQILTQEDWNVVLFNGMEKTSHWAALYFVALMTFGNYVLFNLLVAILVEGFS 1456 HSP 13 Score: 53.9138 bits (128), Expect = 2.548e-6 Identity = 26/88 (29.55%), Postives = 48/88 (54.55%), Query Frame = 1 Query: 1195 NFDNIGFAWVAIFQVISMESWVDIMYYVQDA----------HSFWDWIYFVALIIIGSFFMINLCLVVIASQFSETKRRETERMWIER 1428 NFD++G A +++F + S + WV+IMY DA ++ W +YF+A I++ FF++N+ + V+ F + + + I R Sbjct: 2330 NFDDLGKALMSLFVLSSRDGWVNIMYTGLDAVGVDQQPIVNYNEWRLLYFIAFILLVGFFVLNMFVGVVVENFHRCREEQEKEEKIRR 2417
BLAST of Voltage-dependent T-type calcium channel subunit alpha vs. Ensembl Fly
Match: Ca-alpha1T (gene:FBgn0264386 transcript:FBtr0112953) HSP 1 Score: 784.637 bits (2025), Expect = 0.000e+0 Identity = 446/636 (70.13%), Postives = 534/636 (83.96%), Query Frame = 1 Query: 3799 PKGIFAKRYYHSLYVFSVDNQFRQKCQHIVDKKSFDYLVLFFITLNCITLAMERPSIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKFYYCDGPHLQAVKTKNDCLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFHKCQENQXXXXXXXXXXXXXXXXXXXXXHLRAPLYWENYSKWRRTINSVVTSKYFDLAIAGVIGLNVITMATEFHMMPQVLKTALKVFNYFFTSTFVXXXXXXXXXXXXXRYISDKWNQLDMMIVILSIAGVVIDEVESN---FMPINPTIMRVMRVLRIARVLKLLKMASGIRALLDTVIQALPQVGNXXXXXXXXXXXXXXXXVELFGRLECSDINPCVGLGRHAHFENFGMAFLTLFRIATGDNWNGIMKDTLREKCISSEDCQRNCCVSAIIAPIYFVIFXXXXXXXXXXXXXXXXXKHLEESHKMMCDDYELEREVQRDLDEEAKELAREKQL 5697 PK +R +SLY+F DN+FRQ C V++K FD +VL FI LNCITLAMERP+IPP S ERLFL NY+FT++FT EM IKV++ G+ G AY SGWNIMDG LV IS++DL ++++ S RIFGILRVFRLLR+LRPLRVI+RAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKG FYYC+G +++ V+ ++C + N W N+KYNFD+LG+ALM+LFVLSS+DGWV IMYTG+DAVGV+ QP N+NEW L+YFI+F+LLV FFVLNMFVGVVVENFH+C+E QEKEEK RRAAKRA ++EKKR+ + P Y+ NYS R +++VVTSKYFDLAIA VIGLNV+TMA E++ MP LK ALK+FNYFFT+ F+LEA +KLVALG Y+ D+WNQLD+ IV+LSI G+V++E+E+N +PINPTI+RVMRVLRIARVLKLLKMA+GIRALLDTV+QALPQVGNLGLLFFLLF+IFAALGVELFGRLECSD PC GLG HAHF NFGMAFLTLFR+ATGDNWNGIMKDTLR+ C + DC RNCCVS++IAPI+FVIFVLMAQFVLVNVVVAVLMKHLEESHK M D+ ++E E++R+L E +E A+E++L Sbjct: 2130 PKHFTTEREDYSLYIFPEDNRFRQICTWFVNQKWFDNVVLLFIALNCITLAMERPNIPPSSTERLFLATANYVFTVVFTVEMFIKVVATGMFYGHDAYFTSGWNIMDGSLVTISIIDLLMSLISESSPRIFGILRVFRLLRSLRPLRVINRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGTFYYCEGENIKGVRNADECRRIPGNVWTNRKYNFDDLGKALMSLFVLSSRDGWVNIMYTGLDAVGVDQQPIVNYNEWRLLYFIAFILLVGFFVLNMFVGVVVENFHRCREEQEKEEKIRRAAKRALQMEKKRRRMHEPPYYTNYSPTRMFVHNVVTSKYFDLAIAAVIGLNVVTMAMEYYKMPSGLKYALKIFNYFFTAVFILEANMKLVALGWKLYLKDRWNQLDVGIVLLSIVGIVLEELETNTHQIIPINPTIIRVMRVLRIARVLKLLKMANGIRALLDTVMQALPQVGNLGLLFFLLFFIFAALGVELFGRLECSDEIPCQGLGEHAHFANFGMAFLTLFRVATGDNWNGIMKDTLRDNCDDAADCVRNCCVSSVIAPIFFVIFVLMAQFVLVNVVVAVLMKHLEESHKQMEDELDMEVELERELVRE-QEFAQEQKL 2764 HSP 2 Score: 417.157 bits (1071), Expect = 4.045e-117 Identity = 249/435 (57.24%), Postives = 308/435 (70.80%), Query Frame = 1 Query: 295 PNESLIYHGFYATVFHIFHQNKHPRDWCLKIITWPWFEQLSMTIIAVNCITLSMYQPCGDQNCETSKCQIMQAFDYIIFAFFTCEMVIKIIAMGFLGDLGYFGDTWNRLDMFIVIVGSIEILPSTGNNIGLTAIRTIRVLRPLRAINRIPSMRIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQMWQGVLRNRCYLNLNESFRHPGLNLSSFYQINRTLFLNAVDKDFICSTDKNNGILKCSDIPPSIMLLSNNSLQICKQPARPFTDNLPTKHSCVNWNQYYTDCQPGEKNPYEGAINFDNIGFAWVAIFQVISMESWVDIMYYVQDAHSFWDWIYFVALIIIGSFFMINLCLVVIASQFSETKRRETERMWIERRRFNSSNCSSISKD--EPQTCYLEXXXXXXXXXXXXYRRIVKLYNQIQIRHSKTAQG 1593 PN L Y GF Q PR+WCL +IT PWFE++S+ +I +NCITL MYQPC D C T++C+I+Q FD IIFAFF EM IK++AMG G Y D+WNRLD FIV+ G +E + N+ LTAIRTIRVLRPLRAINRIPSMRILVMLLLDTLPMLGNVLLLCFFVFFIFGIIGVQ+W+G+LR RC L E +P L LS +Y+ ++ D+D+ICST ++G+ C + PP + SL +C + A+ F N PT SCVNWNQYYT C+ +NP++G I+FDNIG AWVAIF VIS+E W DIMYYVQDAHSFWDWIYFV LI+IGSFFMINLCLVVIA+QFSETK+RE ERM ER R+ S++ + S + EP TCY EI+K I + + RR++K Y + + + +G Sbjct: 269 PN--LPYPGFPEISIRALTQYTRPRNWCLMLITNPWFERVSILVILLNCITLGMYQPCVDDACVTNRCKILQIFDDIIFAFFALEMTIKMVAMGICGKNTYLADSWNRLDFFIVLAGLLEYVMHV-ENLNLTAIRTIRVLRPLRAINRIPSMRILVMLLLDTLPMLGNVLLLCFFVFFIFGIIGVQLWEGILRQRCSLMRTEGMVYP-LTLSQYYEFSK-------DQDYICSTPNDSGMHLCGNFPPYRI----GSL-VCNEEAKLFDFNEPTNTSCVNWNQYYTTCKQSGENPFQGTISFDNIGMAWVAIFLVISLEGWTDIMYYVQDAHSFWDWIYFVLLIVIGSFFMINLCLVVIATQFSETKKREMERMRQERARYTSTSTLASSTNNSEPATCYAEIVKYIAHLWRRFKRRMLKKYRLYKYQRQQRKEG 687 HSP 3 Score: 298.516 bits (763), Expect = 1.342e-80 Identity = 175/289 (60.55%), Postives = 209/289 (72.32%), Query Frame = 1 Query: 2164 IKTLVNDVKFQRGILIAILINTLSMGIEYHQQPVQLTQTLEFSNIVFSILFLIEMILKLIGEGILGYIKNGFNLFDGIIVVLGVIELCQ-------QGGTSGLSILRTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKFCTI-----------------ENNKRTCDRKNFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTSSWAALYFIALMTFGNYVLFNLLVAILVEGFSS--------------ERLDEQKLLHNYRQSL 2916 I+ LV FQ+GIL+AILINTLSMGIEYH QP +LT +E SN+VFS +F +EM+LK++ EG YI NGFN+FDGIIV+L IE+CQ GG SGLS+LRTFRLLRILKLVRFMP LR+QLFVM+RT+DNVA FF+LL+LFIFIFSILGM LFG KFC + + CDRK+F+++LW+ VTVFQILTQEDWN VL+NGM +TS WAALYF+ALMTFGNYVLFNLLVAILVEGFSS ++L E+ L NY + Sbjct: 1224 IRRLVEHKYFQQGILLAILINTLSMGIEYHNQPPELTAIVETSNVVFSGIFAVEMLLKVVAEGPFRYIANGFNVFDGIIVILSAIEICQTFMGNGTGGGGSGLSVLRTFRLLRILKLVRFMPNLRRQLFVMLRTMDNVAVFFSLLVLFIFIFSILGMYLFGGKFCKFLDESGLERECTCPEIISRHPQCECDRKHFNNILWATVTVFQILTQEDWNVVLFNGMEKTSHWAALYFVALMTFGNYVLFNLLVAILVEGFSSERNERREREQRELVKKLREETLAENYSDGM 1512 HSP 4 Score: 107.842 bits (268), Expect = 1.216e-22 Identity = 87/345 (25.22%), Postives = 166/345 (48.12%), Query Frame = 1 Query: 3706 ESQNSSRMNNVEDPDEEDMEAMIC--------LSKCCPQPKGIF-AKRYYHSLY--VFSVDNQFRQKCQHIVDKKSFDYLVLFFITLNCITLAMERPSIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDL---FITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKF-YYCDGPHLQAVKTKNDCL-KYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENF 4692 + Q +SRM P ME C LS +P+ R S+Y + V + R+ + +V+ K F +L I +N +++ +E + PP + +N +F+ IF EM++KV+++G Y+ +G+N+ DG +V +S +++ F+ G +LR FRLLR L+ +R + P L+ + +L ++ + + F IF ILG+ LF GKF + D L+ T + + ++ Q E + +F+N+ A + +F + +++ W +++ G+ E + WA +YF++ + + + N+ V ++VE F Sbjct: 1157 QGQGNSRMREPRAPTGNYMEDYACCYDLYQNALSPLDERPRQRSPTTRCLISVYRCMSRVCSWIRRYIRRLVEHKYFQQGILLAILINTLSMGIEYHNQPPELTA--IVETSNVVFSGIFAVEMLLKVVAEGPF----RYIANGFNVFDGIIVILSAIEICQTFMGNGTGGGGSGLSVLRTFRLLRILKLVRFM---PNLRRQLFVMLRTMDNVAVFFSLLVLFIFIFSILGMYLFGGKFCKFLDESGLERECTCPEIISRHPQCEC--DRKHFNNILWATVTVFQILTQEDWNVVLFNGM----------EKTSHWAALYFVALMTFGNYVLFNLLVAILVEGF 1480 HSP 5 Score: 82.0333 bits (201), Expect = 6.756e-15 Identity = 80/308 (25.97%), Postives = 139/308 (45.13%), Query Frame = 1 Query: 2173 LVNDVKFQRGILIAILINTLSMGIEYHQQPVQLTQTL--EFSNIVFSILFLIEMILKLIGEGIL----GYIKNGFNLFDGIIVVLGVIELCQQGGTSGLSILRTFRLLRILK---------LVRFMPALR---QQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKF--CTIEN-----NKRTCDR----------KNFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTS----------SWAALYFIALMTFGNYVLFNLLVAILVEGFSSERLDEQKLLHNYRQSLKKRRANNKQLRIMQH 2961 VN F +L+ I +N +++ +E P T+ L +N VF+++F +EM +K++ G+ Y +G+N+ DG +V + +I+L + S R F +LR+ + ++ P L+ Q L +R I N+ + F IF ILG+ LF F C EN N C R NFD L +++++F + +++ W ++Y G+ W LYFIA + + + N+ V ++VE F R +EQ+ R++ K+ K+ R M Sbjct: 2158 FVNQKWFDNVVLLFIALNCITLAMERPNIPPSSTERLFLATANYVFTVVFTVEMFIKVVATGMFYGHDAYFTSGWNIMDGSLVTISIIDLLMSLISE--SSPRIFGILRVFRLLRSLRPLRVINRAPGLKLVVQTLLSSLRPIGNIV---LICCTFFIIFGILGVQLFKGTFYYCEGENIKGVRNADECRRIPGNVWTNRKYNFDDLGKALMSLFVLSSRDGWVNIMYTGLDAVGVDQQPIVNYNEWRLLYFIAFILLVGFFVLNMFVGVVVENFHRCR-EEQEKEEKIRRAAKRALQMEKKRRRMHE 2459 HSP 6 Score: 81.2629 bits (199), Expect = 1.380e-14 Identity = 60/173 (34.68%), Postives = 93/173 (53.76%), Query Frame = 1 Query: 3865 RQKCQHIVDKKSFDYLVLFFITLNCITLAMERPSIPPH--SKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKG 4377 R C ++ F+ + + I LNCITL M +P + + L + + I F EM IK+++ G+ G YL WN +D F+V LL+ + H + L R +R LRPLR I+R P ++++V LL +L +GN++L+C F IFGI+GVQL++G Sbjct: 291 RNWCLMLITNPWFERVSILVILLNCITLGMYQPCVDDACVTNRCKILQIFDDIIFAFFALEMTIKMVAMGI-CGKNTYLADSWNRLDFFIVLAGLLEYVM-----HVENLN--LTAIRTIRVLRPLRAINRIPSMRILVMLLLDTLPMLGNVLLLCFFVFFIFGIIGVQLWEG 455 HSP 7 Score: 72.4034 bits (176), Expect = 5.636e-12 Identity = 52/207 (25.12%), Postives = 104/207 (50.24%), Query Frame = 1 Query: 2164 IKTLVNDVKFQRGILIAILINTLSMGIEYHQQPVQLTQTLEFSNIVFSILFLIEMILKLIGEGILGYIKNGFNLFDGIIVVLGVIELCQQGGTSG-----------LSILRTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKFCTIE-NNKRTCDRKNFDSLLWSIVTVFQILTQEDWNTVL 2748 + +V F I I +N ++M +EY++ P L L+ N F+ +F++E +KL+ G Y+K+ +N D IV+L ++ + + + + ++R R+ R+LKL++ +R L +++ + V L L FIF+ LG+ LFG C+ E + + +F + + +T+F++ T ++WN ++ Sbjct: 2473 VHNVVTSKYFDLAIAAVIGLNVVTMAMEYYKMPSGLKYALKIFNYFFTAVFILEANMKLVALGWKLYLKDRWNQLDVGIVLLSIVGIVLEELETNTHQIIPINPTIIRVMRVLRIARVLKLLKMANGIRALLDTVMQALPQVGNLGLLFFLLFFIFAALGVELFGRLECSDEIPCQGLGEHAHFANFGMAFLTLFRVATGDNWNGIM 2679 HSP 8 Score: 67.0106 bits (162), Expect = 2.211e-10 Identity = 46/152 (30.26%), Postives = 73/152 (48.03%), Query Frame = 1 Query: 337 FHIFHQNKHPRDWCLKIITWPWFEQLSMTIIAVNCITLSMYQPCGDQNCETSKCQ--IMQAFDYIIFAFFTCEMVIKIIAMG-FLGDLGYFGDTWNRLDMFIVIVGSIEILPSTGNNIGLTAIRTIRVLRPL---------RAINRIPSMRI 756 +IF ++ R C + WF+ + + IA+NCITL+M +P N S + + +Y+ FT EM IK++A G F G YF WN +D +V + I++L S I ++ R +LR R INR P +++ Sbjct: 2142 LYIFPEDNRFRQICTWFVNQKWFDNVVLLFIALNCITLAMERP----NIPPSSTERLFLATANYVFTVVFTVEMFIKVVATGMFYGHDAYFTSGWNIMDGSLVTISIIDLLMSL---ISESSPRIFGILRVFRLLRSLRPLRVINRAPGLKL 2286 HSP 9 Score: 67.0106 bits (162), Expect = 2.248e-10 Identity = 71/228 (31.14%), Postives = 110/228 (48.25%), Query Frame = 1 Query: 4819 RRTINSVVTSKYFDLAIAGVIGLNVITMATEFHMMPQVLKTALKVFNYFFTSTFVXXXXXXXXXXXXXRYISDKWNQLDMMIVILSIAGVVIDEVESNFM----PINPTIMRVMRVLRIARVLKLLKMASGIRALLDTVIQALPQVGNXXXXXXXXXXXXXXXXVELFGRLECSDINPCVGLGRHA-----------------HFENFGMAFLTLFRIATGDNWNGIM 5439 RR I +V KYF I I +N ++M E+H P L ++ N F+ F +E LLK+VA G RYI++ +N D +IVILS E+ FM + + V+R R+ R+LKL++ +R L +++ + V L L +IF+ LG+ LFG C ++ GL R HF N A +T+F+I T ++WN ++ Sbjct: 1221 RRYIRRLVEHKYFQQGILLAILINTLSMGIEYHNQPPELTAIVETSNVVFSGIFAVEMLLKVVAEGPFRYIANGFNVFDGIIVILSAI-----EICQTFMGNGTGGGGSGLSVLRTFRLLRILKLVRFMPNLRRQLFVMLRTMDNVAVFFSLLVLFIFIFSILGMYLFGGKFCKFLDES-GLERECTCPEIISRHPQCECDRKHFNNILWATVTVFQILTQEDWNVVL 1442 HSP 10 Score: 56.225 bits (134), Expect = 5.260e-7 Identity = 37/136 (27.21%), Postives = 75/136 (55.15%), Query Frame = 1 Query: 2173 LVNDVKFQRGILIAILINTLSMGIEYHQQP-------VQLTQTLE-FSNIVFSILFLIEMILKLIGEGILG---YIKNGFNLFDGIIVVLGVIELCQQGGTSGLSILRTFRLLRILKLVRFMPALRQQLFVMIRTI 2547 L+ + F+R ++ IL+N +++G+ QP + L+ F +I+F+ F +EM +K++ GI G Y+ + +N D IV+ G++E L+ +RT R+LR L+ + +P++R + +++ T+ Sbjct: 297 LITNPWFERVSILVILLNCITLGM---YQPCVDDACVTNRCKILQIFDDIIFA-FFALEMTIKMVAMGICGKNTYLADSWNRLDFFIVLAGLLEYVMHVENLNLTAIRTIRVLRPLRAINRIPSMRILVMLLLDTL 428 HSP 11 Score: 54.6842 bits (130), Expect = 1.313e-6 Identity = 27/94 (28.72%), Postives = 53/94 (56.38%), Query Frame = 1 Query: 4432 CLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFHKCQENQ 4713 C + +N ++ +FDN+G A +A+F++ S +GW IMY DA H+ W IYF+ +++ +FF++N+ + V+ F + ++ + Sbjct: 540 CKQSGENPFQG-TISFDNIGMAWVAIFLVISLEGWTDIMYYVQDA----------HSFWDWIYFVLLIVIGSFFMINLCLVVIATQFSETKKRE 622 HSP 12 Score: 53.9138 bits (128), Expect = 2.465e-6 Identity = 26/88 (29.55%), Postives = 48/88 (54.55%), Query Frame = 1 Query: 1195 NFDNIGFAWVAIFQVISMESWVDIMYYVQDA----------HSFWDWIYFVALIIIGSFFMINLCLVVIASQFSETKRRETERMWIER 1428 NFD++G A +++F + S + WV+IMY DA ++ W +YF+A I++ FF++N+ + V+ F + + + I R Sbjct: 2355 NFDDLGKALMSLFVLSSRDGWVNIMYTGLDAVGVDQQPIVNYNEWRLLYFIAFILLVGFFVLNMFVGVVVENFHRCREEQEKEEKIRR 2442 HSP 13 Score: 53.5286 bits (127), Expect = 3.391e-6 Identity = 21/64 (32.81%), Postives = 40/64 (62.50%), Query Frame = 1 Query: 1195 NFDNIGFAWVAIFQVISMESWVDIMYYVQDAHSFWDWIYFVALIIIGSFFMINLCLVVIASQFS 1386 +F+NI +A V +FQ+++ E W +++ + S W +YFVAL+ G++ + NL + ++ FS Sbjct: 1418 HFNNILWATVTVFQILTQEDWNVVLFNGMEKTSHWAALYFVALMTFGNYVLFNLLVAILVEGFS 1481
BLAST of Voltage-dependent T-type calcium channel subunit alpha vs. Ensembl Fly
Match: Ca-alpha1T (gene:FBgn0264386 transcript:FBtr0089393) HSP 1 Score: 784.637 bits (2025), Expect = 0.000e+0 Identity = 446/636 (70.13%), Postives = 534/636 (83.96%), Query Frame = 1 Query: 3799 PKGIFAKRYYHSLYVFSVDNQFRQKCQHIVDKKSFDYLVLFFITLNCITLAMERPSIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKFYYCDGPHLQAVKTKNDCLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFHKCQENQXXXXXXXXXXXXXXXXXXXXXHLRAPLYWENYSKWRRTINSVVTSKYFDLAIAGVIGLNVITMATEFHMMPQVLKTALKVFNYFFTSTFVXXXXXXXXXXXXXRYISDKWNQLDMMIVILSIAGVVIDEVESN---FMPINPTIMRVMRVLRIARVLKLLKMASGIRALLDTVIQALPQVGNXXXXXXXXXXXXXXXXVELFGRLECSDINPCVGLGRHAHFENFGMAFLTLFRIATGDNWNGIMKDTLREKCISSEDCQRNCCVSAIIAPIYFVIFXXXXXXXXXXXXXXXXXKHLEESHKMMCDDYELEREVQRDLDEEAKELAREKQL 5697 PK +R +SLY+F DN+FRQ C V++K FD +VL FI LNCITLAMERP+IPP S ERLFL NY+FT++FT EM IKV++ G+ G AY SGWNIMDG LV IS++DL ++++ S RIFGILRVFRLLR+LRPLRVI+RAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKG FYYC+G +++ V+ ++C + N W N+KYNFD+LG+ALM+LFVLSS+DGWV IMYTG+DAVGV+ QP N+NEW L+YFI+F+LLV FFVLNMFVGVVVENFH+C+E QEKEEK RRAAKRA ++EKKR+ + P Y+ NYS R +++VVTSKYFDLAIA VIGLNV+TMA E++ MP LK ALK+FNYFFT+ F+LEA +KLVALG Y+ D+WNQLD+ IV+LSI G+V++E+E+N +PINPTI+RVMRVLRIARVLKLLKMA+GIRALLDTV+QALPQVGNLGLLFFLLF+IFAALGVELFGRLECSD PC GLG HAHF NFGMAFLTLFR+ATGDNWNGIMKDTLR+ C + DC RNCCVS++IAPI+FVIFVLMAQFVLVNVVVAVLMKHLEESHK M D+ ++E E++R+L E +E A+E++L Sbjct: 2113 PKHFTTEREDYSLYIFPEDNRFRQICTWFVNQKWFDNVVLLFIALNCITLAMERPNIPPSSTERLFLATANYVFTVVFTVEMFIKVVATGMFYGHDAYFTSGWNIMDGSLVTISIIDLLMSLISESSPRIFGILRVFRLLRSLRPLRVINRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGTFYYCEGENIKGVRNADECRRIPGNVWTNRKYNFDDLGKALMSLFVLSSRDGWVNIMYTGLDAVGVDQQPIVNYNEWRLLYFIAFILLVGFFVLNMFVGVVVENFHRCREEQEKEEKIRRAAKRALQMEKKRRRMHEPPYYTNYSPTRMFVHNVVTSKYFDLAIAAVIGLNVVTMAMEYYKMPSGLKYALKIFNYFFTAVFILEANMKLVALGWKLYLKDRWNQLDVGIVLLSIVGIVLEELETNTHQIIPINPTIIRVMRVLRIARVLKLLKMANGIRALLDTVMQALPQVGNLGLLFFLLFFIFAALGVELFGRLECSDEIPCQGLGEHAHFANFGMAFLTLFRVATGDNWNGIMKDTLRDNCDDAADCVRNCCVSSVIAPIFFVIFVLMAQFVLVNVVVAVLMKHLEESHKQMEDELDMEVELERELVRE-QEFAQEQKL 2747 HSP 2 Score: 417.157 bits (1071), Expect = 3.265e-117 Identity = 249/435 (57.24%), Postives = 308/435 (70.80%), Query Frame = 1 Query: 295 PNESLIYHGFYATVFHIFHQNKHPRDWCLKIITWPWFEQLSMTIIAVNCITLSMYQPCGDQNCETSKCQIMQAFDYIIFAFFTCEMVIKIIAMGFLGDLGYFGDTWNRLDMFIVIVGSIEILPSTGNNIGLTAIRTIRVLRPLRAINRIPSMRIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQMWQGVLRNRCYLNLNESFRHPGLNLSSFYQINRTLFLNAVDKDFICSTDKNNGILKCSDIPPSIMLLSNNSLQICKQPARPFTDNLPTKHSCVNWNQYYTDCQPGEKNPYEGAINFDNIGFAWVAIFQVISMESWVDIMYYVQDAHSFWDWIYFVALIIIGSFFMINLCLVVIASQFSETKRRETERMWIERRRFNSSNCSSISKD--EPQTCYLEXXXXXXXXXXXXYRRIVKLYNQIQIRHSKTAQG 1593 PN L Y GF Q PR+WCL +IT PWFE++S+ +I +NCITL MYQPC D C T++C+I+Q FD IIFAFF EM IK++AMG G Y D+WNRLD FIV+ G +E + N+ LTAIRTIRVLRPLRAINRIPSMRILVMLLLDTLPMLGNVLLLCFFVFFIFGIIGVQ+W+G+LR RC L E +P L LS +Y+ ++ D+D+ICST ++G+ C + PP + SL +C + A+ F N PT SCVNWNQYYT C+ +NP++G I+FDNIG AWVAIF VIS+E W DIMYYVQDAHSFWDWIYFV LI+IGSFFMINLCLVVIA+QFSETK+RE ERM ER R+ S++ + S + EP TCY EI+K I + + RR++K Y + + + +G Sbjct: 269 PN--LPYPGFPEISIRALTQYTRPRNWCLMLITNPWFERVSILVILLNCITLGMYQPCVDDACVTNRCKILQIFDDIIFAFFALEMTIKMVAMGICGKNTYLADSWNRLDFFIVLAGLLEYVMHV-ENLNLTAIRTIRVLRPLRAINRIPSMRILVMLLLDTLPMLGNVLLLCFFVFFIFGIIGVQLWEGILRQRCSLMRTEGMVYP-LTLSQYYEFSK-------DQDYICSTPNDSGMHLCGNFPPYRI----GSL-VCNEEAKLFDFNEPTNTSCVNWNQYYTTCKQSGENPFQGTISFDNIGMAWVAIFLVISLEGWTDIMYYVQDAHSFWDWIYFVLLIVIGSFFMINLCLVVIATQFSETKKREMERMRQERARYTSTSTLASSTNNSEPATCYAEIVKYIAHLWRRFKRRMLKKYRLYKYQRQQRKEG 687 HSP 3 Score: 322.783 bits (826), Expect = 4.264e-88 Identity = 181/272 (66.54%), Postives = 212/272 (77.94%), Query Frame = 1 Query: 2164 IKTLVNDVKFQRGILIAILINTLSMGIEYHQQPVQLTQTLEFSNIVFSILFLIEMILKLIGEGILGYIKNGFNLFDGIIVVLGVIELCQ-------QGGTSGLSILRTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKFCTIENNKRTCDRKNFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTSSWAALYFIALMTFGNYVLFNLLVAILVEGFSS--------------ERLDEQKLLHNYRQSL 2916 I+ LV FQ+GIL+AILINTLSMGIEYH QP +LT +E SN+VFS +F +EM+LK++ EG YI NGFN+FDGIIV+L IE+CQ GG SGLS+LRTFRLLRILKLVRFMP LR+QLFVM+RT+DNVA FF+LL+LFIFIFSILGM+LFGCKFC N + CDRKNFDSLLW++VTVFQILTQEDWN VL+NGM +TS WAALYF+ALMTFGNYVLFNLLVAILVEGFSS ++L E+ L NY + Sbjct: 1224 IRRLVEHKYFQQGILLAILINTLSMGIEYHNQPPELTAIVETSNVVFSGIFAVEMLLKVVAEGPFRYIANGFNVFDGIIVILSAIEICQTFMGNGTGGGGSGLSVLRTFRLLRILKLVRFMPNLRRQLFVMLRTMDNVAVFFSLLVLFIFIFSILGMNLFGCKFCEKVNGEMICDRKNFDSLLWALVTVFQILTQEDWNVVLFNGMEKTSHWAALYFVALMTFGNYVLFNLLVAILVEGFSSERNERREREQRELVKKLREETLAENYSDGM 1495 HSP 4 Score: 107.457 bits (267), Expect = 1.278e-22 Identity = 87/343 (25.36%), Postives = 159/343 (46.36%), Query Frame = 1 Query: 3706 ESQNSSRMNNVEDPDEEDMEAMIC--------LSKCCPQPKGIF-AKRYYHSLY--VFSVDNQFRQKCQHIVDKKSFDYLVLFFITLNCITLAMERPSIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDL---FITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKFYYCDGPHLQAVKTKNDCLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENF 4692 + Q +SRM P ME C LS +P+ R S+Y + V + R+ + +V+ K F +L I +N +++ +E + PP + +N +F+ IF EM++KV+++G Y+ +G+N+ DG +V +S +++ F+ G +LR FRLLR L+ +R + P L+ + +L ++ + + F IF ILG+ LF KF C K + E + NFD+L AL+ +F + +++ W +++ G+ E + WA +YF++ + + + N+ V ++VE F Sbjct: 1157 QGQGNSRMREPRAPTGNYMEDYACCYDLYQNALSPLDERPRQRSPTTRCLISVYRCMSRVCSWIRRYIRRLVEHKYFQQGILLAILINTLSMGIEYHNQPPELTA--IVETSNVVFSGIFAVEMLLKVVAEGPF----RYIANGFNVFDGIIVILSAIEICQTFMGNGTGGGGSGLSVLRTFRLLRILKLVRFM---PNLRRQLFVMLRTMDNVAVFFSLLVLFIFIFSILGMNLFGCKF----------------CEKVN-GEMICDRKNFDSLLWALVTVFQILTQEDWNVVLFNGM----------EKTSHWAALYFVALMTFGNYVLFNLLVAILVEGF 1463 HSP 5 Score: 82.0333 bits (201), Expect = 7.343e-15 Identity = 80/308 (25.97%), Postives = 139/308 (45.13%), Query Frame = 1 Query: 2173 LVNDVKFQRGILIAILINTLSMGIEYHQQPVQLTQTL--EFSNIVFSILFLIEMILKLIGEGIL----GYIKNGFNLFDGIIVVLGVIELCQQGGTSGLSILRTFRLLRILK---------LVRFMPALR---QQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKF--CTIEN-----NKRTCDR----------KNFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTS----------SWAALYFIALMTFGNYVLFNLLVAILVEGFSSERLDEQKLLHNYRQSLKKRRANNKQLRIMQH 2961 VN F +L+ I +N +++ +E P T+ L +N VF+++F +EM +K++ G+ Y +G+N+ DG +V + +I+L + S R F +LR+ + ++ P L+ Q L +R I N+ + F IF ILG+ LF F C EN N C R NFD L +++++F + +++ W ++Y G+ W LYFIA + + + N+ V ++VE F R +EQ+ R++ K+ K+ R M Sbjct: 2141 FVNQKWFDNVVLLFIALNCITLAMERPNIPPSSTERLFLATANYVFTVVFTVEMFIKVVATGMFYGHDAYFTSGWNIMDGSLVTISIIDLLMSLISE--SSPRIFGILRVFRLLRSLRPLRVINRAPGLKLVVQTLLSSLRPIGNIV---LICCTFFIIFGILGVQLFKGTFYYCEGENIKGVRNADECRRIPGNVWTNRKYNFDDLGKALMSLFVLSSRDGWVNIMYTGLDAVGVDQQPIVNYNEWRLLYFIAFILLVGFFVLNMFVGVVVENFHRCR-EEQEKEEKIRRAAKRALQMEKKRRRMHE 2442 HSP 6 Score: 81.2629 bits (199), Expect = 1.289e-14 Identity = 60/173 (34.68%), Postives = 93/173 (53.76%), Query Frame = 1 Query: 3865 RQKCQHIVDKKSFDYLVLFFITLNCITLAMERPSIPPH--SKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKG 4377 R C ++ F+ + + I LNCITL M +P + + L + + I F EM IK+++ G+ G YL WN +D F+V LL+ + H + L R +R LRPLR I+R P ++++V LL +L +GN++L+C F IFGI+GVQL++G Sbjct: 291 RNWCLMLITNPWFERVSILVILLNCITLGMYQPCVDDACVTNRCKILQIFDDIIFAFFALEMTIKMVAMGI-CGKNTYLADSWNRLDFFIVLAGLLEYVM-----HVENLN--LTAIRTIRVLRPLRAINRIPSMRILVMLLLDTLPMLGNVLLLCFFVFFIFGIIGVQLWEG 455 HSP 7 Score: 72.4034 bits (176), Expect = 5.633e-12 Identity = 52/207 (25.12%), Postives = 104/207 (50.24%), Query Frame = 1 Query: 2164 IKTLVNDVKFQRGILIAILINTLSMGIEYHQQPVQLTQTLEFSNIVFSILFLIEMILKLIGEGILGYIKNGFNLFDGIIVVLGVIELCQQGGTSG-----------LSILRTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKFCTIE-NNKRTCDRKNFDSLLWSIVTVFQILTQEDWNTVL 2748 + +V F I I +N ++M +EY++ P L L+ N F+ +F++E +KL+ G Y+K+ +N D IV+L ++ + + + + ++R R+ R+LKL++ +R L +++ + V L L FIF+ LG+ LFG C+ E + + +F + + +T+F++ T ++WN ++ Sbjct: 2456 VHNVVTSKYFDLAIAAVIGLNVVTMAMEYYKMPSGLKYALKIFNYFFTAVFILEANMKLVALGWKLYLKDRWNQLDVGIVLLSIVGIVLEELETNTHQIIPINPTIIRVMRVLRIARVLKLLKMANGIRALLDTVMQALPQVGNLGLLFFLLFFIFAALGVELFGRLECSDEIPCQGLGEHAHFANFGMAFLTLFRVATGDNWNGIM 2662 HSP 8 Score: 71.2478 bits (173), Expect = 1.360e-11 Identity = 68/211 (32.23%), Postives = 110/211 (52.13%), Query Frame = 1 Query: 4819 RRTINSVVTSKYFDLAIAGVIGLNVITMATEFHMMPQVLKTALKVFNYFFTSTFVXXXXXXXXXXXXXRYISDKWNQLDMMIVILSIAGVVIDEVESNFM----PINPTIMRVMRVLRIARVLKLLKMASGIRALLDTVIQALPQVGNXXXXXXXXXXXXXXXXVELFGRLECSDINPCVGLGRHAHFENFGMAFLTLFRIATGDNWNGIM 5439 RR I +V KYF I I +N ++M E+H P L ++ N F+ F +E LLK+VA G RYI++ +N D +IVILS E+ FM + + V+R R+ R+LKL++ +R L +++ + V L L +IF+ LG+ LFG C +N + R +F++ A +T+F+I T ++WN ++ Sbjct: 1221 RRYIRRLVEHKYFQQGILLAILINTLSMGIEYHNQPPELTAIVETSNVVFSGIFAVEMLLKVVAEGPFRYIANGFNVFDGIIVILSAI-----EICQTFMGNGTGGGGSGLSVLRTFRLLRILKLVRFMPNLRRQLFVMLRTMDNVAVFFSLLVLFIFIFSILGMNLFGCKFCEKVNGEMICDRK-NFDSLLWALVTVFQILTQEDWNVVL 1425 HSP 9 Score: 67.3958 bits (163), Expect = 2.173e-10 Identity = 46/152 (30.26%), Postives = 73/152 (48.03%), Query Frame = 1 Query: 337 FHIFHQNKHPRDWCLKIITWPWFEQLSMTIIAVNCITLSMYQPCGDQNCETSKCQ--IMQAFDYIIFAFFTCEMVIKIIAMG-FLGDLGYFGDTWNRLDMFIVIVGSIEILPSTGNNIGLTAIRTIRVLRPL---------RAINRIPSMRI 756 +IF ++ R C + WF+ + + IA+NCITL+M +P N S + + +Y+ FT EM IK++A G F G YF WN +D +V + I++L S I ++ R +LR R INR P +++ Sbjct: 2125 LYIFPEDNRFRQICTWFVNQKWFDNVVLLFIALNCITLAMERP----NIPPSSTERLFLATANYVFTVVFTVEMFIKVVATGMFYGHDAYFTSGWNIMDGSLVTISIIDLLMSL---ISESSPRIFGILRVFRLLRSLRPLRVINRAPGLKL 2269 HSP 10 Score: 55.8398 bits (133), Expect = 5.576e-7 Identity = 37/136 (27.21%), Postives = 75/136 (55.15%), Query Frame = 1 Query: 2173 LVNDVKFQRGILIAILINTLSMGIEYHQQP-------VQLTQTLE-FSNIVFSILFLIEMILKLIGEGILG---YIKNGFNLFDGIIVVLGVIELCQQGGTSGLSILRTFRLLRILKLVRFMPALRQQLFVMIRTI 2547 L+ + F+R ++ IL+N +++G+ QP + L+ F +I+F+ F +EM +K++ GI G Y+ + +N D IV+ G++E L+ +RT R+LR L+ + +P++R + +++ T+ Sbjct: 297 LITNPWFERVSILVILLNCITLGM---YQPCVDDACVTNRCKILQIFDDIIFA-FFALEMTIKMVAMGICGKNTYLADSWNRLDFFIVLAGLLEYVMHVENLNLTAIRTIRVLRPLRAINRIPSMRILVMLLLDTL 428 HSP 11 Score: 54.6842 bits (130), Expect = 1.369e-6 Identity = 21/64 (32.81%), Postives = 40/64 (62.50%), Query Frame = 1 Query: 1195 NFDNIGFAWVAIFQVISMESWVDIMYYVQDAHSFWDWIYFVALIIIGSFFMINLCLVVIASQFS 1386 NFD++ +A V +FQ+++ E W +++ + S W +YFVAL+ G++ + NL + ++ FS Sbjct: 1401 NFDSLLWALVTVFQILTQEDWNVVLFNGMEKTSHWAALYFVALMTFGNYVLFNLLVAILVEGFS 1464 HSP 12 Score: 54.6842 bits (130), Expect = 1.381e-6 Identity = 27/94 (28.72%), Postives = 53/94 (56.38%), Query Frame = 1 Query: 4432 CLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFHKCQENQ 4713 C + +N ++ +FDN+G A +A+F++ S +GW IMY DA H+ W IYF+ +++ +FF++N+ + V+ F + ++ + Sbjct: 540 CKQSGENPFQG-TISFDNIGMAWVAIFLVISLEGWTDIMYYVQDA----------HSFWDWIYFVLLIVIGSFFMINLCLVVIATQFSETKKRE 622 HSP 13 Score: 53.9138 bits (128), Expect = 2.506e-6 Identity = 26/88 (29.55%), Postives = 48/88 (54.55%), Query Frame = 1 Query: 1195 NFDNIGFAWVAIFQVISMESWVDIMYYVQDA----------HSFWDWIYFVALIIIGSFFMINLCLVVIASQFSETKRRETERMWIER 1428 NFD++G A +++F + S + WV+IMY DA ++ W +YF+A I++ FF++N+ + V+ F + + + I R Sbjct: 2338 NFDDLGKALMSLFVLSSRDGWVNIMYTGLDAVGVDQQPIVNYNEWRLLYFIAFILLVGFFVLNMFVGVVVENFHRCREEQEKEEKIRR 2425
BLAST of Voltage-dependent T-type calcium channel subunit alpha vs. Ensembl Fly
Match: Ca-alpha1T (gene:FBgn0264386 transcript:FBtr0304610) HSP 1 Score: 784.252 bits (2024), Expect = 0.000e+0 Identity = 446/636 (70.13%), Postives = 534/636 (83.96%), Query Frame = 1 Query: 3799 PKGIFAKRYYHSLYVFSVDNQFRQKCQHIVDKKSFDYLVLFFITLNCITLAMERPSIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKFYYCDGPHLQAVKTKNDCLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFHKCQENQXXXXXXXXXXXXXXXXXXXXXHLRAPLYWENYSKWRRTINSVVTSKYFDLAIAGVIGLNVITMATEFHMMPQVLKTALKVFNYFFTSTFVXXXXXXXXXXXXXRYISDKWNQLDMMIVILSIAGVVIDEVESN---FMPINPTIMRVMRVLRIARVLKLLKMASGIRALLDTVIQALPQVGNXXXXXXXXXXXXXXXXVELFGRLECSDINPCVGLGRHAHFENFGMAFLTLFRIATGDNWNGIMKDTLREKCISSEDCQRNCCVSAIIAPIYFVIFXXXXXXXXXXXXXXXXXKHLEESHKMMCDDYELEREVQRDLDEEAKELAREKQL 5697 PK +R +SLY+F DN+FRQ C V++K FD +VL FI LNCITLAMERP+IPP S ERLFL NY+FT++FT EM IKV++ G+ G AY SGWNIMDG LV IS++DL ++++ S RIFGILRVFRLLR+LRPLRVI+RAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKG FYYC+G +++ V+ ++C + N W N+KYNFD+LG+ALM+LFVLSS+DGWV IMYTG+DAVGV+ QP N+NEW L+YFI+F+LLV FFVLNMFVGVVVENFH+C+E QEKEEK RRAAKRA ++EKKR+ + P Y+ NYS R +++VVTSKYFDLAIA VIGLNV+TMA E++ MP LK ALK+FNYFFT+ F+LEA +KLVALG Y+ D+WNQLD+ IV+LSI G+V++E+E+N +PINPTI+RVMRVLRIARVLKLLKMA+GIRALLDTV+QALPQVGNLGLLFFLLF+IFAALGVELFGRLECSD PC GLG HAHF NFGMAFLTLFR+ATGDNWNGIMKDTLR+ C + DC RNCCVS++IAPI+FVIFVLMAQFVLVNVVVAVLMKHLEESHK M D+ ++E E++R+L E +E A+E++L Sbjct: 2125 PKHFTTEREDYSLYIFPEDNRFRQICTWFVNQKWFDNVVLLFIALNCITLAMERPNIPPSSTERLFLATANYVFTVVFTVEMFIKVVATGMFYGHDAYFTSGWNIMDGSLVTISIIDLLMSLISESSPRIFGILRVFRLLRSLRPLRVINRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGTFYYCEGENIKGVRNADECRRIPGNVWTNRKYNFDDLGKALMSLFVLSSRDGWVNIMYTGLDAVGVDQQPIVNYNEWRLLYFIAFILLVGFFVLNMFVGVVVENFHRCREEQEKEEKIRRAAKRALQMEKKRRRMHEPPYYTNYSPTRMFVHNVVTSKYFDLAIAAVIGLNVVTMAMEYYKMPSGLKYALKIFNYFFTAVFILEANMKLVALGWKLYLKDRWNQLDVGIVLLSIVGIVLEELETNTHQIIPINPTIIRVMRVLRIARVLKLLKMANGIRALLDTVMQALPQVGNLGLLFFLLFFIFAALGVELFGRLECSDEIPCQGLGEHAHFANFGMAFLTLFRVATGDNWNGIMKDTLRDNCDDAADCVRNCCVSSVIAPIFFVIFVLMAQFVLVNVVVAVLMKHLEESHKQMEDELDMEVELERELVRE-QEFAQEQKL 2759 HSP 2 Score: 416.772 bits (1070), Expect = 4.757e-117 Identity = 249/426 (58.45%), Postives = 305/426 (71.60%), Query Frame = 1 Query: 295 PNESLIYHGFYATVFHIFHQNKHPRDWCLKIITWPWFEQLSMTIIAVNCITLSMYQPCGDQNCETSKCQIMQAFDYIIFAFFTCEMVIKIIAMGFLGDLGYFGDTWNRLDMFIVIVGSIEILPSTGNNIGLTAIRTIRVLRPLRAINRIPSMRIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQMWQGVLRNRCYLNLNESFRHPGLNLSSFYQINRTLFLNAVDKDFICSTDKNNGILKCSDIPPSIMLLSNNSLQICKQPARPFTDNLPTKHSCVNWNQYYTDCQPGEKNPYEGAINFDNIGFAWVAIFQVISMESWVDIMYYVQDAHSFWDWIYFVALIIIGSFFMINLCLVVIASQFSETKRRETERMWIERRRFNSSNCSSISKD--EPQTCYLEXXXXXXXXXXXXYRRIVKLYNQIQ 1566 PN L Y GF Q PR+WCL +IT PWFE++S+ +I +NCITL MYQPC D C T++C+I+Q FD IIFAFF EM IK++AMG G Y D+WNRLD FIV+ G +E + N+ LTAIRTIRVLRPLRAINRIPSMRILVMLLLDTLPMLGNVLLLCFFVFFIFGIIGVQ+W+G+LR RC L E +P L LS +Y+ ++ D+D+ICST ++G+ C + PP + SL +C + A+ F N PT SCVNWNQYYT C+ +NP++G I+FDNIG AWVAIF VIS+E W DIMYYVQDAHSFWDWIYFV LI+IGSFFMINLCLVVIA+QFSETK+RE ERM ER R+ S++ + S + EP TCY EI+K I + + RR++K Y + Q Sbjct: 269 PN--LPYPGFPEISIRALTQYTRPRNWCLMLITNPWFERVSILVILLNCITLGMYQPCVDDACVTNRCKILQIFDDIIFAFFALEMTIKMVAMGICGKNTYLADSWNRLDFFIVLAGLLEYVMHV-ENLNLTAIRTIRVLRPLRAINRIPSMRILVMLLLDTLPMLGNVLLLCFFVFFIFGIIGVQLWEGILRQRCSLMRTEGMVYP-LTLSQYYEFSK-------DQDYICSTPNDSGMHLCGNFPPYRI----GSL-VCNEEAKLFDFNEPTNTSCVNWNQYYTTCKQSGENPFQGTISFDNIGMAWVAIFLVISLEGWTDIMYYVQDAHSFWDWIYFVLLIVIGSFFMINLCLVVIATQFSETKKREMERMRQERARYTSTSTLASSTNNSEPATCYAEIVKYIAHLWRRFKRRMLKKYQRQQ 678 HSP 3 Score: 298.13 bits (762), Expect = 1.509e-80 Identity = 175/289 (60.55%), Postives = 209/289 (72.32%), Query Frame = 1 Query: 2164 IKTLVNDVKFQRGILIAILINTLSMGIEYHQQPVQLTQTLEFSNIVFSILFLIEMILKLIGEGILGYIKNGFNLFDGIIVVLGVIELCQ-------QGGTSGLSILRTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKFCTI-----------------ENNKRTCDRKNFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTSSWAALYFIALMTFGNYVLFNLLVAILVEGFSS--------------ERLDEQKLLHNYRQSL 2916 I+ LV FQ+GIL+AILINTLSMGIEYH QP +LT +E SN+VFS +F +EM+LK++ EG YI NGFN+FDGIIV+L IE+CQ GG SGLS+LRTFRLLRILKLVRFMP LR+QLFVM+RT+DNVA FF+LL+LFIFIFSILGM LFG KFC + + CDRK+F+++LW+ VTVFQILTQEDWN VL+NGM +TS WAALYF+ALMTFGNYVLFNLLVAILVEGFSS ++L E+ L NY + Sbjct: 1219 IRRLVEHKYFQQGILLAILINTLSMGIEYHNQPPELTAIVETSNVVFSGIFAVEMLLKVVAEGPFRYIANGFNVFDGIIVILSAIEICQTFMGNGTGGGGSGLSVLRTFRLLRILKLVRFMPNLRRQLFVMLRTMDNVAVFFSLLVLFIFIFSILGMYLFGGKFCKFLDESGLERECTCPEIISRHPQCECDRKHFNNILWATVTVFQILTQEDWNVVLFNGMEKTSHWAALYFVALMTFGNYVLFNLLVAILVEGFSSERNERREREQRELVKKLREETLAENYSDGM 1507 HSP 4 Score: 107.842 bits (268), Expect = 1.216e-22 Identity = 87/345 (25.22%), Postives = 166/345 (48.12%), Query Frame = 1 Query: 3706 ESQNSSRMNNVEDPDEEDMEAMIC--------LSKCCPQPKGIF-AKRYYHSLY--VFSVDNQFRQKCQHIVDKKSFDYLVLFFITLNCITLAMERPSIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDL---FITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKF-YYCDGPHLQAVKTKNDCL-KYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENF 4692 + Q +SRM P ME C LS +P+ R S+Y + V + R+ + +V+ K F +L I +N +++ +E + PP + +N +F+ IF EM++KV+++G Y+ +G+N+ DG +V +S +++ F+ G +LR FRLLR L+ +R + P L+ + +L ++ + + F IF ILG+ LF GKF + D L+ T + + ++ Q E + +F+N+ A + +F + +++ W +++ G+ E + WA +YF++ + + + N+ V ++VE F Sbjct: 1152 QGQGNSRMREPRAPTGNYMEDYACCYDLYQNALSPLDERPRQRSPTTRCLISVYRCMSRVCSWIRRYIRRLVEHKYFQQGILLAILINTLSMGIEYHNQPPELTA--IVETSNVVFSGIFAVEMLLKVVAEGPF----RYIANGFNVFDGIIVILSAIEICQTFMGNGTGGGGSGLSVLRTFRLLRILKLVRFM---PNLRRQLFVMLRTMDNVAVFFSLLVLFIFIFSILGMYLFGGKFCKFLDESGLERECTCPEIISRHPQCEC--DRKHFNNILWATVTVFQILTQEDWNVVLFNGM----------EKTSHWAALYFVALMTFGNYVLFNLLVAILVEGF 1475 HSP 5 Score: 82.0333 bits (201), Expect = 7.224e-15 Identity = 80/308 (25.97%), Postives = 139/308 (45.13%), Query Frame = 1 Query: 2173 LVNDVKFQRGILIAILINTLSMGIEYHQQPVQLTQTL--EFSNIVFSILFLIEMILKLIGEGIL----GYIKNGFNLFDGIIVVLGVIELCQQGGTSGLSILRTFRLLRILK---------LVRFMPALR---QQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKF--CTIEN-----NKRTCDR----------KNFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTS----------SWAALYFIALMTFGNYVLFNLLVAILVEGFSSERLDEQKLLHNYRQSLKKRRANNKQLRIMQH 2961 VN F +L+ I +N +++ +E P T+ L +N VF+++F +EM +K++ G+ Y +G+N+ DG +V + +I+L + S R F +LR+ + ++ P L+ Q L +R I N+ + F IF ILG+ LF F C EN N C R NFD L +++++F + +++ W ++Y G+ W LYFIA + + + N+ V ++VE F R +EQ+ R++ K+ K+ R M Sbjct: 2153 FVNQKWFDNVVLLFIALNCITLAMERPNIPPSSTERLFLATANYVFTVVFTVEMFIKVVATGMFYGHDAYFTSGWNIMDGSLVTISIIDLLMSLISE--SSPRIFGILRVFRLLRSLRPLRVINRAPGLKLVVQTLLSSLRPIGNIV---LICCTFFIIFGILGVQLFKGTFYYCEGENIKGVRNADECRRIPGNVWTNRKYNFDDLGKALMSLFVLSSRDGWVNIMYTGLDAVGVDQQPIVNYNEWRLLYFIAFILLVGFFVLNMFVGVVVENFHRCR-EEQEKEEKIRRAAKRALQMEKKRRRMHE 2454 HSP 6 Score: 80.8777 bits (198), Expect = 1.438e-14 Identity = 60/173 (34.68%), Postives = 93/173 (53.76%), Query Frame = 1 Query: 3865 RQKCQHIVDKKSFDYLVLFFITLNCITLAMERPSIPPH--SKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKG 4377 R C ++ F+ + + I LNCITL M +P + + L + + I F EM IK+++ G+ G YL WN +D F+V LL+ + H + L R +R LRPLR I+R P ++++V LL +L +GN++L+C F IFGI+GVQL++G Sbjct: 291 RNWCLMLITNPWFERVSILVILLNCITLGMYQPCVDDACVTNRCKILQIFDDIIFAFFALEMTIKMVAMGI-CGKNTYLADSWNRLDFFIVLAGLLEYVM-----HVENLN--LTAIRTIRVLRPLRAINRIPSMRILVMLLLDTLPMLGNVLLLCFFVFFIFGIIGVQLWEG 455 HSP 7 Score: 72.4034 bits (176), Expect = 5.877e-12 Identity = 52/207 (25.12%), Postives = 104/207 (50.24%), Query Frame = 1 Query: 2164 IKTLVNDVKFQRGILIAILINTLSMGIEYHQQPVQLTQTLEFSNIVFSILFLIEMILKLIGEGILGYIKNGFNLFDGIIVVLGVIELCQQGGTSG-----------LSILRTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKFCTIE-NNKRTCDRKNFDSLLWSIVTVFQILTQEDWNTVL 2748 + +V F I I +N ++M +EY++ P L L+ N F+ +F++E +KL+ G Y+K+ +N D IV+L ++ + + + + ++R R+ R+LKL++ +R L +++ + V L L FIF+ LG+ LFG C+ E + + +F + + +T+F++ T ++WN ++ Sbjct: 2468 VHNVVTSKYFDLAIAAVIGLNVVTMAMEYYKMPSGLKYALKIFNYFFTAVFILEANMKLVALGWKLYLKDRWNQLDVGIVLLSIVGIVLEELETNTHQIIPINPTIIRVMRVLRIARVLKLLKMANGIRALLDTVMQALPQVGNLGLLFFLLFFIFAALGVELFGRLECSDEIPCQGLGEHAHFANFGMAFLTLFRVATGDNWNGIM 2674 HSP 8 Score: 67.0106 bits (162), Expect = 2.286e-10 Identity = 46/152 (30.26%), Postives = 73/152 (48.03%), Query Frame = 1 Query: 337 FHIFHQNKHPRDWCLKIITWPWFEQLSMTIIAVNCITLSMYQPCGDQNCETSKCQ--IMQAFDYIIFAFFTCEMVIKIIAMG-FLGDLGYFGDTWNRLDMFIVIVGSIEILPSTGNNIGLTAIRTIRVLRPL---------RAINRIPSMRI 756 +IF ++ R C + WF+ + + IA+NCITL+M +P N S + + +Y+ FT EM IK++A G F G YF WN +D +V + I++L S I ++ R +LR R INR P +++ Sbjct: 2137 LYIFPEDNRFRQICTWFVNQKWFDNVVLLFIALNCITLAMERP----NIPPSSTERLFLATANYVFTVVFTVEMFIKVVATGMFYGHDAYFTSGWNIMDGSLVTISIIDLLMSL---ISESSPRIFGILRVFRLLRSLRPLRVINRAPGLKL 2281 HSP 9 Score: 67.0106 bits (162), Expect = 2.615e-10 Identity = 71/228 (31.14%), Postives = 110/228 (48.25%), Query Frame = 1 Query: 4819 RRTINSVVTSKYFDLAIAGVIGLNVITMATEFHMMPQVLKTALKVFNYFFTSTFVXXXXXXXXXXXXXRYISDKWNQLDMMIVILSIAGVVIDEVESNFM----PINPTIMRVMRVLRIARVLKLLKMASGIRALLDTVIQALPQVGNXXXXXXXXXXXXXXXXVELFGRLECSDINPCVGLGRHA-----------------HFENFGMAFLTLFRIATGDNWNGIM 5439 RR I +V KYF I I +N ++M E+H P L ++ N F+ F +E LLK+VA G RYI++ +N D +IVILS E+ FM + + V+R R+ R+LKL++ +R L +++ + V L L +IF+ LG+ LFG C ++ GL R HF N A +T+F+I T ++WN ++ Sbjct: 1216 RRYIRRLVEHKYFQQGILLAILINTLSMGIEYHNQPPELTAIVETSNVVFSGIFAVEMLLKVVAEGPFRYIANGFNVFDGIIVILSAI-----EICQTFMGNGTGGGGSGLSVLRTFRLLRILKLVRFMPNLRRQLFVMLRTMDNVAVFFSLLVLFIFIFSILGMYLFGGKFCKFLDES-GLERECTCPEIISRHPQCECDRKHFNNILWATVTVFQILTQEDWNVVL 1437 HSP 10 Score: 55.8398 bits (133), Expect = 5.485e-7 Identity = 37/136 (27.21%), Postives = 75/136 (55.15%), Query Frame = 1 Query: 2173 LVNDVKFQRGILIAILINTLSMGIEYHQQP-------VQLTQTLE-FSNIVFSILFLIEMILKLIGEGILG---YIKNGFNLFDGIIVVLGVIELCQQGGTSGLSILRTFRLLRILKLVRFMPALRQQLFVMIRTI 2547 L+ + F+R ++ IL+N +++G+ QP + L+ F +I+F+ F +EM +K++ GI G Y+ + +N D IV+ G++E L+ +RT R+LR L+ + +P++R + +++ T+ Sbjct: 297 LITNPWFERVSILVILLNCITLGM---YQPCVDDACVTNRCKILQIFDDIIFA-FFALEMTIKMVAMGICGKNTYLADSWNRLDFFIVLAGLLEYVMHVENLNLTAIRTIRVLRPLRAINRIPSMRILVMLLLDTL 428 HSP 11 Score: 54.6842 bits (130), Expect = 1.324e-6 Identity = 27/94 (28.72%), Postives = 53/94 (56.38%), Query Frame = 1 Query: 4432 CLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFHKCQENQ 4713 C + +N ++ +FDN+G A +A+F++ S +GW IMY DA H+ W IYF+ +++ +FF++N+ + V+ F + ++ + Sbjct: 540 CKQSGENPFQG-TISFDNIGMAWVAIFLVISLEGWTDIMYYVQDA----------HSFWDWIYFVLLIVIGSFFMINLCLVVIATQFSETKKRE 622 HSP 12 Score: 53.9138 bits (128), Expect = 2.465e-6 Identity = 26/88 (29.55%), Postives = 48/88 (54.55%), Query Frame = 1 Query: 1195 NFDNIGFAWVAIFQVISMESWVDIMYYVQDA----------HSFWDWIYFVALIIIGSFFMINLCLVVIASQFSETKRRETERMWIER 1428 NFD++G A +++F + S + WV+IMY DA ++ W +YF+A I++ FF++N+ + V+ F + + + I R Sbjct: 2350 NFDDLGKALMSLFVLSSRDGWVNIMYTGLDAVGVDQQPIVNYNEWRLLYFIAFILLVGFFVLNMFVGVVVENFHRCREEQEKEEKIRR 2437 HSP 13 Score: 53.5286 bits (127), Expect = 3.391e-6 Identity = 21/64 (32.81%), Postives = 40/64 (62.50%), Query Frame = 1 Query: 1195 NFDNIGFAWVAIFQVISMESWVDIMYYVQDAHSFWDWIYFVALIIIGSFFMINLCLVVIASQFS 1386 +F+NI +A V +FQ+++ E W +++ + S W +YFVAL+ G++ + NL + ++ FS Sbjct: 1413 HFNNILWATVTVFQILTQEDWNVVLFNGMEKTSHWAALYFVALMTFGNYVLFNLLVAILVEGFS 1476
BLAST of Voltage-dependent T-type calcium channel subunit alpha vs. Ensembl Fly
Match: Ca-alpha1T (gene:FBgn0264386 transcript:FBtr0334984) HSP 1 Score: 784.252 bits (2024), Expect = 0.000e+0 Identity = 446/636 (70.13%), Postives = 534/636 (83.96%), Query Frame = 1 Query: 3799 PKGIFAKRYYHSLYVFSVDNQFRQKCQHIVDKKSFDYLVLFFITLNCITLAMERPSIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKFYYCDGPHLQAVKTKNDCLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFHKCQENQXXXXXXXXXXXXXXXXXXXXXHLRAPLYWENYSKWRRTINSVVTSKYFDLAIAGVIGLNVITMATEFHMMPQVLKTALKVFNYFFTSTFVXXXXXXXXXXXXXRYISDKWNQLDMMIVILSIAGVVIDEVESN---FMPINPTIMRVMRVLRIARVLKLLKMASGIRALLDTVIQALPQVGNXXXXXXXXXXXXXXXXVELFGRLECSDINPCVGLGRHAHFENFGMAFLTLFRIATGDNWNGIMKDTLREKCISSEDCQRNCCVSAIIAPIYFVIFXXXXXXXXXXXXXXXXXKHLEESHKMMCDDYELEREVQRDLDEEAKELAREKQL 5697 PK +R +SLY+F DN+FRQ C V++K FD +VL FI LNCITLAMERP+IPP S ERLFL NY+FT++FT EM IKV++ G+ G AY SGWNIMDG LV IS++DL ++++ S RIFGILRVFRLLR+LRPLRVI+RAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKG FYYC+G +++ V+ ++C + N W N+KYNFD+LG+ALM+LFVLSS+DGWV IMYTG+DAVGV+ QP N+NEW L+YFI+F+LLV FFVLNMFVGVVVENFH+C+E QEKEEK RRAAKRA ++EKKR+ + P Y+ NYS R +++VVTSKYFDLAIA VIGLNV+TMA E++ MP LK ALK+FNYFFT+ F+LEA +KLVALG Y+ D+WNQLD+ IV+LSI G+V++E+E+N +PINPTI+RVMRVLRIARVLKLLKMA+GIRALLDTV+QALPQVGNLGLLFFLLF+IFAALGVELFGRLECSD PC GLG HAHF NFGMAFLTLFR+ATGDNWNGIMKDTLR+ C + DC RNCCVS++IAPI+FVIFVLMAQFVLVNVVVAVLMKHLEESHK M D+ ++E E++R+L E +E A+E++L Sbjct: 2143 PKHFTTEREDYSLYIFPEDNRFRQICTWFVNQKWFDNVVLLFIALNCITLAMERPNIPPSSTERLFLATANYVFTVVFTVEMFIKVVATGMFYGHDAYFTSGWNIMDGSLVTISIIDLLMSLISESSPRIFGILRVFRLLRSLRPLRVINRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGTFYYCEGENIKGVRNADECRRIPGNVWTNRKYNFDDLGKALMSLFVLSSRDGWVNIMYTGLDAVGVDQQPIVNYNEWRLLYFIAFILLVGFFVLNMFVGVVVENFHRCREEQEKEEKIRRAAKRALQMEKKRRRMHEPPYYTNYSPTRMFVHNVVTSKYFDLAIAAVIGLNVVTMAMEYYKMPSGLKYALKIFNYFFTAVFILEANMKLVALGWKLYLKDRWNQLDVGIVLLSIVGIVLEELETNTHQIIPINPTIIRVMRVLRIARVLKLLKMANGIRALLDTVMQALPQVGNLGLLFFLLFFIFAALGVELFGRLECSDEIPCQGLGEHAHFANFGMAFLTLFRVATGDNWNGIMKDTLRDNCDDAADCVRNCCVSSVIAPIFFVIFVLMAQFVLVNVVVAVLMKHLEESHKQMEDELDMEVELERELVRE-QEFAQEQKL 2777 HSP 2 Score: 409.838 bits (1052), Expect = 7.466e-115 Identity = 247/441 (56.01%), Postives = 308/441 (69.84%), Query Frame = 1 Query: 295 PNESLIYHGFYATVFHIFHQNKHPRDWCLKIITWPWFEQLSMTIIAVNCITLSMYQPCGDQNCETSKCQIMQAFDYIIFAFFTCEMVIKIIAMGFLGDLGYFGDTWNRLDMFIVIVGSIEILPSTGNNIGLTAIRTIRVLRPLRAINRIPSMRIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQMWQGVLRNRCYLNLNESFRHPGLNLSSFYQINRTL------FLNAVDKDFICSTDKNNGILKCSDIPPSIMLLSNNSLQICKQPARPFTDNLPTKHSCVNWNQYYTDCQPGEKNPYEGAINFDNIGFAWVAIFQVISMESWVDIMYYVQDAHSFWDWIYFVALIIIGSFFMINLCLVVIASQFSETKRRETERMWIERRRFNSSNCSSISKD--EPQTCYLEXXXXXXXXXXXXYRRIVKLYNQIQIRHSKTAQG 1593 PN L Y GF Q PR+WCL +IT PWFE++S+ +I +NCITL MYQPC D C T++C+I+Q FD IIFAFF EM IK++AMG G Y D+WNRLD FIV+ G +E + N+ LTAIRTIRVLRPLRAINRIPSMRILVMLLLDTLPMLGNVLLLCFFVFFIFGIIGVQ+W+G+LR RC L E +P L + Y++ + + + D+D+ICST ++G+ C + PP + SL +C + A+ F N PT SCVNWNQYYT C+ +NP++G I+FDNIG AWVAIF VIS+E W DIMYYVQDAHSFWDWIYFV LI+IGSFFMINLCLVVIA+QFSETK+RE ERM ER R+ S++ + S + EP TCY EI+K I + + RR++K Y + + + +G Sbjct: 269 PN--LPYPGFPEISIRALTQYTRPRNWCLMLITNPWFERVSILVILLNCITLGMYQPCVDDACVTNRCKILQIFDDIIFAFFALEMTIKMVAMGICGKNTYLADSWNRLDFFIVLAGLLEYVMHV-ENLNLTAIRTIRVLRPLRAINRIPSMRILVMLLLDTLPMLGNVLLLCFFVFFIFGIIGVQLWEGILRQRCSLMRTEGMVYP-LTVPEVYRVRVRVNSLSQYYEFSKDQDYICSTPNDSGMHLCGNFPPYRI----GSL-VCNEEAKLFDFNEPTNTSCVNWNQYYTTCKQSGENPFQGTISFDNIGMAWVAIFLVISLEGWTDIMYYVQDAHSFWDWIYFVLLIVIGSFFMINLCLVVIATQFSETKKREMERMRQERARYTSTSTLASSTNNSEPATCYAEIVKYIAHLWRRFKRRMLKKYRLYKYQRQQRKEG 700 HSP 3 Score: 298.13 bits (762), Expect = 1.453e-80 Identity = 175/289 (60.55%), Postives = 209/289 (72.32%), Query Frame = 1 Query: 2164 IKTLVNDVKFQRGILIAILINTLSMGIEYHQQPVQLTQTLEFSNIVFSILFLIEMILKLIGEGILGYIKNGFNLFDGIIVVLGVIELCQ-------QGGTSGLSILRTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKFCTI-----------------ENNKRTCDRKNFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTSSWAALYFIALMTFGNYVLFNLLVAILVEGFSS--------------ERLDEQKLLHNYRQSL 2916 I+ LV FQ+GIL+AILINTLSMGIEYH QP +LT +E SN+VFS +F +EM+LK++ EG YI NGFN+FDGIIV+L IE+CQ GG SGLS+LRTFRLLRILKLVRFMP LR+QLFVM+RT+DNVA FF+LL+LFIFIFSILGM LFG KFC + + CDRK+F+++LW+ VTVFQILTQEDWN VL+NGM +TS WAALYF+ALMTFGNYVLFNLLVAILVEGFSS ++L E+ L NY + Sbjct: 1237 IRRLVEHKYFQQGILLAILINTLSMGIEYHNQPPELTAIVETSNVVFSGIFAVEMLLKVVAEGPFRYIANGFNVFDGIIVILSAIEICQTFMGNGTGGGGSGLSVLRTFRLLRILKLVRFMPNLRRQLFVMLRTMDNVAVFFSLLVLFIFIFSILGMYLFGGKFCKFLDESGLERECTCPEIISRHPQCECDRKHFNNILWATVTVFQILTQEDWNVVLFNGMEKTSHWAALYFVALMTFGNYVLFNLLVAILVEGFSSERNERREREQRELVKKLREETLAENYSDGM 1525 HSP 4 Score: 107.457 bits (267), Expect = 1.258e-22 Identity = 87/345 (25.22%), Postives = 166/345 (48.12%), Query Frame = 1 Query: 3706 ESQNSSRMNNVEDPDEEDMEAMIC--------LSKCCPQPKGIF-AKRYYHSLY--VFSVDNQFRQKCQHIVDKKSFDYLVLFFITLNCITLAMERPSIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDL---FITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKF-YYCDGPHLQAVKTKNDCL-KYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENF 4692 + Q +SRM P ME C LS +P+ R S+Y + V + R+ + +V+ K F +L I +N +++ +E + PP + +N +F+ IF EM++KV+++G Y+ +G+N+ DG +V +S +++ F+ G +LR FRLLR L+ +R + P L+ + +L ++ + + F IF ILG+ LF GKF + D L+ T + + ++ Q E + +F+N+ A + +F + +++ W +++ G+ E + WA +YF++ + + + N+ V ++VE F Sbjct: 1170 QGQGNSRMREPRAPTGNYMEDYACCYDLYQNALSPLDERPRQRSPTTRCLISVYRCMSRVCSWIRRYIRRLVEHKYFQQGILLAILINTLSMGIEYHNQPPELTA--IVETSNVVFSGIFAVEMLLKVVAEGPF----RYIANGFNVFDGIIVILSAIEICQTFMGNGTGGGGSGLSVLRTFRLLRILKLVRFM---PNLRRQLFVMLRTMDNVAVFFSLLVLFIFIFSILGMYLFGGKFCKFLDESGLERECTCPEIISRHPQCEC--DRKHFNNILWATVTVFQILTQEDWNVVLFNGM----------EKTSHWAALYFVALMTFGNYVLFNLLVAILVEGF 1493 HSP 5 Score: 82.0333 bits (201), Expect = 6.991e-15 Identity = 80/308 (25.97%), Postives = 139/308 (45.13%), Query Frame = 1 Query: 2173 LVNDVKFQRGILIAILINTLSMGIEYHQQPVQLTQTL--EFSNIVFSILFLIEMILKLIGEGIL----GYIKNGFNLFDGIIVVLGVIELCQQGGTSGLSILRTFRLLRILK---------LVRFMPALR---QQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKF--CTIEN-----NKRTCDR----------KNFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTS----------SWAALYFIALMTFGNYVLFNLLVAILVEGFSSERLDEQKLLHNYRQSLKKRRANNKQLRIMQH 2961 VN F +L+ I +N +++ +E P T+ L +N VF+++F +EM +K++ G+ Y +G+N+ DG +V + +I+L + S R F +LR+ + ++ P L+ Q L +R I N+ + F IF ILG+ LF F C EN N C R NFD L +++++F + +++ W ++Y G+ W LYFIA + + + N+ V ++VE F R +EQ+ R++ K+ K+ R M Sbjct: 2171 FVNQKWFDNVVLLFIALNCITLAMERPNIPPSSTERLFLATANYVFTVVFTVEMFIKVVATGMFYGHDAYFTSGWNIMDGSLVTISIIDLLMSLISE--SSPRIFGILRVFRLLRSLRPLRVINRAPGLKLVVQTLLSSLRPIGNIV---LICCTFFIIFGILGVQLFKGTFYYCEGENIKGVRNADECRRIPGNVWTNRKYNFDDLGKALMSLFVLSSRDGWVNIMYTGLDAVGVDQQPIVNYNEWRLLYFIAFILLVGFFVLNMFVGVVVENFHRCR-EEQEKEEKIRRAAKRALQMEKKRRRMHE 2472 HSP 6 Score: 80.8777 bits (198), Expect = 1.427e-14 Identity = 60/173 (34.68%), Postives = 93/173 (53.76%), Query Frame = 1 Query: 3865 RQKCQHIVDKKSFDYLVLFFITLNCITLAMERPSIPPH--SKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKG 4377 R C ++ F+ + + I LNCITL M +P + + L + + I F EM IK+++ G+ G YL WN +D F+V LL+ + H + L R +R LRPLR I+R P ++++V LL +L +GN++L+C F IFGI+GVQL++G Sbjct: 291 RNWCLMLITNPWFERVSILVILLNCITLGMYQPCVDDACVTNRCKILQIFDDIIFAFFALEMTIKMVAMGI-CGKNTYLADSWNRLDFFIVLAGLLEYVM-----HVENLN--LTAIRTIRVLRPLRAINRIPSMRILVMLLLDTLPMLGNVLLLCFFVFFIFGIIGVQLWEG 455 HSP 7 Score: 72.4034 bits (176), Expect = 5.686e-12 Identity = 52/207 (25.12%), Postives = 104/207 (50.24%), Query Frame = 1 Query: 2164 IKTLVNDVKFQRGILIAILINTLSMGIEYHQQPVQLTQTLEFSNIVFSILFLIEMILKLIGEGILGYIKNGFNLFDGIIVVLGVIELCQQGGTSG-----------LSILRTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKFCTIE-NNKRTCDRKNFDSLLWSIVTVFQILTQEDWNTVL 2748 + +V F I I +N ++M +EY++ P L L+ N F+ +F++E +KL+ G Y+K+ +N D IV+L ++ + + + + ++R R+ R+LKL++ +R L +++ + V L L FIF+ LG+ LFG C+ E + + +F + + +T+F++ T ++WN ++ Sbjct: 2486 VHNVVTSKYFDLAIAAVIGLNVVTMAMEYYKMPSGLKYALKIFNYFFTAVFILEANMKLVALGWKLYLKDRWNQLDVGIVLLSIVGIVLEELETNTHQIIPINPTIIRVMRVLRIARVLKLLKMANGIRALLDTVMQALPQVGNLGLLFFLLFFIFAALGVELFGRLECSDEIPCQGLGEHAHFANFGMAFLTLFRVATGDNWNGIM 2692 HSP 8 Score: 67.3958 bits (163), Expect = 2.157e-10 Identity = 46/152 (30.26%), Postives = 73/152 (48.03%), Query Frame = 1 Query: 337 FHIFHQNKHPRDWCLKIITWPWFEQLSMTIIAVNCITLSMYQPCGDQNCETSKCQ--IMQAFDYIIFAFFTCEMVIKIIAMG-FLGDLGYFGDTWNRLDMFIVIVGSIEILPSTGNNIGLTAIRTIRVLRPL---------RAINRIPSMRI 756 +IF ++ R C + WF+ + + IA+NCITL+M +P N S + + +Y+ FT EM IK++A G F G YF WN +D +V + I++L S I ++ R +LR R INR P +++ Sbjct: 2155 LYIFPEDNRFRQICTWFVNQKWFDNVVLLFIALNCITLAMERP----NIPPSSTERLFLATANYVFTVVFTVEMFIKVVATGMFYGHDAYFTSGWNIMDGSLVTISIIDLLMSL---ISESSPRIFGILRVFRLLRSLRPLRVINRAPGLKL 2299 HSP 9 Score: 67.0106 bits (162), Expect = 2.326e-10 Identity = 71/228 (31.14%), Postives = 110/228 (48.25%), Query Frame = 1 Query: 4819 RRTINSVVTSKYFDLAIAGVIGLNVITMATEFHMMPQVLKTALKVFNYFFTSTFVXXXXXXXXXXXXXRYISDKWNQLDMMIVILSIAGVVIDEVESNFM----PINPTIMRVMRVLRIARVLKLLKMASGIRALLDTVIQALPQVGNXXXXXXXXXXXXXXXXVELFGRLECSDINPCVGLGRHA-----------------HFENFGMAFLTLFRIATGDNWNGIM 5439 RR I +V KYF I I +N ++M E+H P L ++ N F+ F +E LLK+VA G RYI++ +N D +IVILS E+ FM + + V+R R+ R+LKL++ +R L +++ + V L L +IF+ LG+ LFG C ++ GL R HF N A +T+F+I T ++WN ++ Sbjct: 1234 RRYIRRLVEHKYFQQGILLAILINTLSMGIEYHNQPPELTAIVETSNVVFSGIFAVEMLLKVVAEGPFRYIANGFNVFDGIIVILSAI-----EICQTFMGNGTGGGGSGLSVLRTFRLLRILKLVRFMPNLRRQLFVMLRTMDNVAVFFSLLVLFIFIFSILGMYLFGGKFCKFLDES-GLERECTCPEIISRHPQCECDRKHFNNILWATVTVFQILTQEDWNVVL 1455 HSP 10 Score: 56.225 bits (134), Expect = 5.306e-7 Identity = 37/136 (27.21%), Postives = 75/136 (55.15%), Query Frame = 1 Query: 2173 LVNDVKFQRGILIAILINTLSMGIEYHQQP-------VQLTQTLE-FSNIVFSILFLIEMILKLIGEGILG---YIKNGFNLFDGIIVVLGVIELCQQGGTSGLSILRTFRLLRILKLVRFMPALRQQLFVMIRTI 2547 L+ + F+R ++ IL+N +++G+ QP + L+ F +I+F+ F +EM +K++ GI G Y+ + +N D IV+ G++E L+ +RT R+LR L+ + +P++R + +++ T+ Sbjct: 297 LITNPWFERVSILVILLNCITLGM---YQPCVDDACVTNRCKILQIFDDIIFA-FFALEMTIKMVAMGICGKNTYLADSWNRLDFFIVLAGLLEYVMHVENLNLTAIRTIRVLRPLRAINRIPSMRILVMLLLDTL 428 HSP 11 Score: 54.6842 bits (130), Expect = 1.325e-6 Identity = 27/94 (28.72%), Postives = 53/94 (56.38%), Query Frame = 1 Query: 4432 CLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFHKCQENQ 4713 C + +N ++ +FDN+G A +A+F++ S +GW IMY DA H+ W IYF+ +++ +FF++N+ + V+ F + ++ + Sbjct: 553 CKQSGENPFQG-TISFDNIGMAWVAIFLVISLEGWTDIMYYVQDA----------HSFWDWIYFVLLIVIGSFFMINLCLVVIATQFSETKKRE 635 HSP 12 Score: 53.9138 bits (128), Expect = 2.507e-6 Identity = 26/88 (29.55%), Postives = 48/88 (54.55%), Query Frame = 1 Query: 1195 NFDNIGFAWVAIFQVISMESWVDIMYYVQDA----------HSFWDWIYFVALIIIGSFFMINLCLVVIASQFSETKRRETERMWIER 1428 NFD++G A +++F + S + WV+IMY DA ++ W +YF+A I++ FF++N+ + V+ F + + + I R Sbjct: 2368 NFDDLGKALMSLFVLSSRDGWVNIMYTGLDAVGVDQQPIVNYNEWRLLYFIAFILLVGFFVLNMFVGVVVENFHRCREEQEKEEKIRR 2455 HSP 13 Score: 53.5286 bits (127), Expect = 3.364e-6 Identity = 21/64 (32.81%), Postives = 40/64 (62.50%), Query Frame = 1 Query: 1195 NFDNIGFAWVAIFQVISMESWVDIMYYVQDAHSFWDWIYFVALIIIGSFFMINLCLVVIASQFS 1386 +F+NI +A V +FQ+++ E W +++ + S W +YFVAL+ G++ + NL + ++ FS Sbjct: 1431 HFNNILWATVTVFQILTQEDWNVVLFNGMEKTSHWAALYFVALMTFGNYVLFNLLVAILVEGFS 1494
BLAST of Voltage-dependent T-type calcium channel subunit alpha vs. Ensembl Zebrafish
Match: cacna1ha (calcium channel, voltage-dependent, T type, alpha 1H subunit a [Source:ZFIN;Acc:ZDB-GENE-130103-1]) HSP 1 Score: 1286.94 bits (3329), Expect = 0.000e+0 Identity = 874/1848 (47.29%), Postives = 1160/1848 (62.77%), Query Frame = 1 Query: 418 MTIIAVNCITLSMYQPCGDQNCETSKCQIMQAFDYIIFAFFTCEMVIKIIAMGFLGDLGYFGDTWNRLDMFIVIVGSIEILPSTGNNIGLTAIRTIRVLRPLRAINRIPSMRIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQMWQGVLRNRCYLNLNESFRHPGLNLSSFYQINRTLFLNAVDKDFICSTDKNNGILKCSDIPP---SIMLLSNNSLQICKQPARPFTDNLPTKHSCVNWNQYYTDCQPGEKNPYEGAINFDNIGFAWVAIFQVISMESWVDIMYYVQDAHSFWDWIYFVALIIIGSFFMINLCLVVIASQFSETKRRETERMWIERRRFNSSNCSSISKDEPQTCYLEXXXXXXXXXXXXYRRIVKLYNQIQIRHSKT------------------AQGNYQNKL-----KRQRKHCNVCLNSRSQFPI-----DDHCHLYSI--------------VNTISGDKQHYYAINKYPINFSNIPPKASPELSVIDVL-------NSPRHPNHLISDISSKSVSTETKRKSQYN---------------------------------SQILLEIPSTPANHSTTRDNYRWELTNNPLLTSKDKVYPQSVASRSSSINSCAYQIPRLTDSYSKHRRPFNKNQNKTKRKNYLSICQQKIKTLVNDVKFQRGILIAILINTLSMGIEYHQQPVQLTQTLEFSNIVFSILFLIEMILKLIGEGILGYIKNGFNLFDGIIVVLGVIELCQQGGTSGLSILRTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKFC-TIENNKRTCDRKNFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTSSWAALYFIALMTFGNYVLFNLLVAILVEGFSSERLDEQKLLHNYRQSLKKRRANNKQLRIMQHQSENLVLLTNSIQKDQTGENQKISSQPPVIIHTAATPMPTPRSSPYNELVXXXXXXXXXXXXXXXQSILSINKSFETTSSRNINTTILQEDASIMPGMKNSKQNLDSTLFVEHHIPVQKTPTSNGLNVKLVSIPIPYTTNRSNFIIPSSILLRQGSINSFMGSVNSDRSKILLDEKKSISETDEKSLSRQSSFKSFMAYKNKINQLTIPFSNRYSLSLDSEGKSNYQFKMNYLLAREKALEEPDDSNSESQNSSRMNNVEDPDEEDMEAMIC--LSKCCPQPKGIFAKRYYH-SLYVFSVDNQFRQKCQHIVDKKSFDYLVLFFITLNCITLAMERPSIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKFYYCDGPHLQAVKTKNDCLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFHKCQENQXXXXXXXXXXXXXXXXXXXXXH-LRAPLYWENYSKWRRTINSVVTSKYFDLAIAGVIGLNVITMATEFHMMPQVLKTALKVFNYFFTSTFVXXXXXXXXXXXXXRYISDKWNQLDMMIVILSIAGVVIDEVESN-FMPINPTIMRVMRVLRIARVLKLLKMASGIRALLDTVIQALPQVGNXXXXXXXXXXXXXXXXVELFGRLECSDINPCVGLGRHAHFENFGMAFLTLFRIATGDNWNGIMKDTLREKCISSEDCQRNCCVSAI--IAPIYFVIFXXXXXXXXXXXXXXXXXKHLEESHKMMCDDYELEREVQRDLDEEAKELA 5682 M +I +NC+TL MYQPC D C++ C ++QAFD IFAFF EMVIK+IA+G G GY GDTWNRLD FIV+ G +E G+N L+AIRT+RVLRPLRAINR+PSMRILV LLLDTLPMLGNVLLLCFFVFFIFGI+GVQ+W G+LRNRC++ ++ L+ S Y N + D FICS+ K+NG+ +CS +PP + N S T N +SCVNWNQYY++C+PG+ NP++GA+NFDNIG+AW+AIFQVI++E WVDIMYYV DAHSF+++IYF+ LII+GSFFMINLCLVVIA+QF+ETK+RE M +R R+ S++ + S EP +CY E++K ++ + K+ RR+ ++YN Q + K G++ + + QR+HC+ L++ S P+ + + SI + +S Q ++I Y +F P + +P + L N P LI + S + + KS N +Q+LLE+ S P Y + L D YP+ S + +Y +T + H+ + QN+ + + ++++ +V+ F RGI+IAILINTLSMGIEYH+QP +LT LE SNIVF+ +F++EM+ KL+ GI GYI+N +N+FDG+IVV+ V E+ GLS+LRTFRLLR+LKLVRF+PALR+QL V+++T+DNVATF LL+LFIF FSILGM LFGCKF +EN DRKNFDSLLW+IVTVFQILTQEDWN VLYNGM TS WAALYF+ALMTFGNYVLFNLLVAILVEGF +E D K +++ + N + ++ Q QS + + D G + PP+I+ TAATPMPTP+SS L F+ T SR + + +A + + +++ P P +G N + + RS++ + L R S+ + +R +L E + E D+ + ++ + L IP + LD G+S ++LA A +DS + EED++ C L + K + K + SLY+FS N+FR CQ ++ K FDY+VL FI LNCIT+A+ERP I ERLFL V+NY+FT+IF EM +KV++ G G+Q+YLKS WN++DG LVF+SL+D+ ++ L NRIFGILRV RLLRTLRPLRVISRAPGLKLVV+TL++SLRPIGNIVLICC FFI+FGILGVQLFKGKF++C+G + + K+DCL+ + +W +KYNFDNLGQALM+LFVLS KDGWV IMY G+DAVGV+ QP+ NHN W L+YFISFLL+V+FFVLNMFVGVVVENFHKC+++QE+ E KR + +EKKR+ LR P Y+ +YS R I+++ T+ Y DL I G+I +NV+TM+ E P L ALK NY FT F++EALLKLVA G+ R+ D+WNQLD+ IV+LSI G+ ++E++ N +PINPTI+R+MRVLRIARVLKLLKMA+G+R+LLDTV+QALPQVGNLGLLF LLF+I+AALGVELFG+LEC++ NPC GL HA FENFGMAFLTLFR++TGDNWNGIMKDTLRE C+ SE C+S + ++PIYFV FVLMAQFVLVNVVVAVLMKHLEES+K +D E++ ++ + +E + L+ Sbjct: 1 MLVILLNCVTLGMYQPCEDLKCQSEWCIVLQAFDDCIFAFFAVEMVIKMIALGIFGINGYLGDTWNRLDFFIVMAGMME-YSLDGHNASLSAIRTVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAGLLRNRCFMPSKVRDQY-NLSYMSLYYENE----DGEDNPFICSSSKDNGMKRCSAVPPLKEGVECTLNASFLGHVYSGLSGTGN----YSCVNWNQYYSECKPGDLNPHKGAVNFDNIGYAWIAIFQVITLEGWVDIMYYVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIATQFAETKQRENMLMKEQRARYRSNDSTLASYSEPGSCYEEMLKYVSHLYRKVKRRLSRIYNSWQSKRRKKVNPNTGAGGGANGHSRHRGYGHWVQSIHSLIQQHQRQHCH--LSNGSPSPVATTGSSEALEMRSITAGQQLTVSSQPTATHNLSSSTQSVHSI--YQGDFREAPQERTPTNVAVPALSRLNGGMNYPTILPSLICNYSGGGSLGKERGKSDANTGHEVIQDFDKLHQQIEAHSHSRVLLQMAGVVPTQLLLEVMSCP---------YCVRALESMDLEIGDSDYPR---SEGDMVYEFSYDAGFITGRSAHHK--MQEKQNRLVQ--FWEDFRERLTRIVDSKYFNRGIMIAILINTLSMGIEYHEQPEELTNILEISNIVFTSMFVLEMLFKLLAFGIFGYIRNPYNIFDGVIVVISVWEIIGH-ADGGLSVLRTFRLLRVLKLVRFLPALRRQLLVLMKTMDNVATFCMLLMLFIFTFSILGMHLFGCKFSLKMENGDTIPDRKNFDSLLWAIVTVFQILTQEDWNVVLYNGMASTSPWAALYFVALMTFGNYVLFNLLVAILVEGFQAEG-DANK-----SDGDEEKTSVNSEEKMEQLQS------SANGHVDPCG-----TLPPPIIMRTAATPMPTPKSS------------------------LGPESVFDLTESRRGSAVSIDPNAFDQKSLSSPRRS-----------PCH--PRGSGSN---------WGSRRSSW----NSLGRAPSLKR--KDTSGERESLLSGEGRGSFEDDDIEAEKLTNISG--GSLQHPSSLDIPELPQMGEYLDCNGRS------QHILADLSASLNKEDSIA---------------EEDLDDSFCFRLRRTLAAYKPKWCKDHEEWSLYLFSPHNKFRMMCQKLISHKMFDYVVLVFIFLNCITIALERPHI--QQSERLFLLVSNYVFTVIFVAEMTVKVVALGFYSGNQSYLKSTWNVLDGVLVFVSLIDILVS-LAWTGNRIFGILRVLRLLRTLRPLRVISRAPGLKLVVETLITSLRPIGNIVLICCAFFIVFGILGVQLFKGKFFHCEGGDTRNITNKSDCLQ-ANLKWIRRKYNFDNLGQALMSLFVLSCKDGWVNIMYDGLDAVGVDQQPERNHNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHKCRQDQEEVEARLLELKRQKLMEKKRRKALRRP-YYADYSPARLYIHTLCTNHYLDLFITGIICINVVTMSIEHFNQPSYLDEALKYCNYVFTIIFIIEALLKLVAFGIRRFFKDRWNQLDLAIVLLSIMGITLEEIKMNAALPINPTIIRIMRVLRIARVLKLLKMATGMRSLLDTVMQALPQVGNLGLLFMLLFFIYAALGVELFGKLECTENNPCEGLSPHATFENFGMAFLTLFRVSTGDNWNGIMKDTLRE-CLPSE----TQCLSYLPWVSPIYFVTFVLMAQFVLVNVVVAVLMKHLEESNKEAKEDAEMDAAIKLAILKETRRLS 1715 HSP 2 Score: 63.5438 bits (153), Expect = 3.550e-9 Identity = 38/119 (31.93%), Postives = 64/119 (53.78%), Query Frame = 1 Query: 337 FHIFHQNKHPRDWCLKIITWPWFEQLSMTIIAVNCITLSMYQPCGDQNCETSKCQIMQAFDYIIFAFFTCEMVIKIIAMGFL-GDLGYFGDTWNRLDMFIVIVGSIEILPS---TGNNI 681 ++F + R C K+I+ F+ + + I +NCIT+++ +P + + S+ + +Y+ F EM +K++A+GF G+ Y TWN LD +V V I+IL S TGN I Sbjct: 1106 LYLFSPHNKFRMMCQKLISHKMFDYVVLVFIFLNCITIALERP----HIQQSERLFLLVSNYVFTVIFVAEMTVKVVALGFYSGNQSYLKSTWNVLDGVLVFVSLIDILVSLAWTGNRI 1220
BLAST of Voltage-dependent T-type calcium channel subunit alpha vs. Ensembl Zebrafish
Match: cacna1hb (calcium channel, voltage-dependent, T type, alpha 1H subunit b [Source:ZFIN;Acc:ZDB-GENE-090312-128]) HSP 1 Score: 633.639 bits (1633), Expect = 0.000e+0 Identity = 384/618 (62.14%), Postives = 490/618 (79.29%), Query Frame = 1 Query: 3832 SLYVFSVDNQFRQKCQHIVDKKSFDYLVLFFITLNCITLAMERPSIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKFYYCDGPHLQAVKTKNDCLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFHKCQENQXXXXXXXXXXXXXXXXXXXXXHLRAPLYWENYSKWRRTINSVVTSKYFDLAIAGVIGLNVITMATEFHMMPQVLKTALKVFNYFFTSTFVXXXXXXXXXXXXXRYISDKWNQLDMMIVILSIAGVVIDEVESNF-MPINPTIMRVMRVLRIARVLKLLKMASGIRALLDTVIQALPQVGNXXXXXXXXXXXXXXXXVELFGRLECSDINPCVGLGRHAHFENFGMAFLTLFRIATGDNWNGIMKDTLREKCISSEDCQRNCC--VSAIIAPIYFVIFXXXXXXXXXXXXXXXXXKHLEESHKMMCDDYELEREVQRDLDEEAKE 5676 SLY+F+ N FR +CQ ++ K FD++VLFFI NCIT+A+ERP I P S ER+FL V+NYIFT+IF EM +KV+S GL G +YLKS WN++DGFLVF+S++D+ +++ NRI GILRV RLLRTLRPLRVISRAPGLKLVV+TL++SLRPIGNIVLICC FFI+FGILGVQLFKGKFY+C+G + + K++CL+ ++ +W +KYNFDNLGQALM+LFVLSSKDGWV IMY G+DAV V+ QP NHN W L+YFISFLL+V+FFVLNMFVGVVVENFHKC+++QE+EE RR KR +R+EKKR+ Y+ +YS R I+++ TS Y DL I +I +NV+TM+ E + P+ L LK NYFFT FV+EA LKLVA G R+ ++WNQLD+ IV+LSI G+ ++E++ N +PINPTI+R+MRVLRIARVLKLLKMA+G+RALLDTV+QALPQVGNLGLLF LLF+I+AALGVELFG+L+C++ NPC GL RHA F+NFGMAFLTLFR++TGDNWNGIMKDTLRE C+ + C +++P+YFV FVLMAQFVLVNVVVAVLMKHLEES+ ++ E++ E++ +L+ ++ Sbjct: 634 SLYLFAPQNNFRMRCQKVITHKMFDHIVLFFIFFNCITIALERPDIQPDSTERIFLKVSNYIFTVIFVAEMTVKVVSLGLYAGPGSYLKSSWNVLDGFLVFVSIVDILVSLASSGGNRILGILRVLRLLRTLRPLRVISRAPGLKLVVETLITSLRPIGNIVLICCAFFIVFGILGVQLFKGKFYHCEGFDTRNITNKSECLQ-AKYKWIRRKYNFDNLGQALMSLFVLSSKDGWVNIMYDGLDAVAVDQQPIRNHNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHKCRQDQEEEEARRREEKRQKRMEKKRRKALQRPYYADYSPTRLYIHTLCTSHYLDLFITIIIAINVLTMSMEHYRQPKYLDEGLKYCNYFFTLVFVIEAALKLVAFGFRRFFKERWNQLDLAIVLLSIMGITLEEIDLNASLPINPTIIRIMRVLRIARVLKLLKMATGMRALLDTVVQALPQVGNLGLLFMLLFFIYAALGVELFGKLDCTEENPCEGLSRHATFQNFGMAFLTLFRVSTGDNWNGIMKDTLRE-------CKNDKCLSYLPLLSPLYFVTFVLMAQFVLVNVVVAVLMKHLEESNIDAREEAEMDAELKLELEAGRRQ 1243 HSP 2 Score: 306.605 bits (784), Expect = 1.734e-83 Identity = 172/285 (60.35%), Postives = 217/285 (76.14%), Query Frame = 1 Query: 2077 DSYSKHRRP-FNKNQNKTKRKNYLSIC----QQKIKTLVNDVKFQRGILIAILINTLSMGIEYHQQPVQLTQTLEFSNIVFSILFLIEMILKLIGEGILGYIKNGFNLFDGIIVVLGVIELCQQGGTSGLSILRTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKFC-TIENNKRTCDRKNFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTSSWAALYFIALMTFGNYVLFNLLVAILVEGFSSER--LDEQKLLHNYR 2907 D S+ R+ + + ++++N + +C + +K +V+ F RGI+IAILINTLSMG+EYH+QP +LT LE SNIVF+ LF++EM+LKL G+ YI N +N+FDGIIV++ V E+ Q G S+LRTFRLLR+LKLVRF+PALR+QL V+++T+DNVATF LL+LFIFIFSILGM LFGCKF +EN DRKNFDSLLW+IVTVFQILTQEDWN VLYNGM TS +AALYF+ALMTFGNYVLFNLLVAILVEGF +E L ++LL Y+ Sbjct: 340 DVGSEQRKTNLDAEEKVSEKRNCVCMCVHYARAVLKRIVDSKYFNRGIMIAILINTLSMGVEYHEQPDELTDVLEISNIVFTSLFVLEMLLKLSACGLFDYISNPYNIFDGIIVIISVCEIVGQA-DGGFSVLRTFRLLRVLKLVRFLPALRRQLVVLMKTMDNVATFCMLLMLFIFIFSILGMHLFGCKFTLRLENGDTVSDRKNFDSLLWAIVTVFQILTQEDWNVVLYNGMASTSPYAALYFVALMTFGNYVLFNLLVAILVEGFQAESWCLILKRLLEPYK 623 HSP 3 Score: 227.254 bits (578), Expect = 4.567e-59 Identity = 113/245 (46.12%), Postives = 162/245 (66.12%), Query Frame = 1 Query: 850 QMWQGVLRNRCYLNLN-ESFRHPGLNLSSFYQINRTLFLNAVDKDFICSTDKNNGILKCSDIPPSIMLLSNNSLQICKQPARPFTDNLPTKHSCVNWNQYYTDCQPGEKNPYEGAINFDNIGFAWVAIFQVISMESWVDIMYYVQDAHSFWDWIYFVALIIIGSFFMINLCLVVIASQFSETKRRETERMWIERRRFNSSNCSSISKDEPQTCYLEXXXXXXXXXXXXYRRIVKLYNQIQIRHSK 1581 Q+W G+LRNRC+ + N + ++S +Y+++ T D FICST++ NG+L+CS++P + ++ L F + H CVNWN YY C E NP+ GAINFDNIG+AW+AIFQVI++E W DIMYYV DAHSF+++IYF+ LII+GSFFMINLCLVVIA+QFSETK+RE + M +R RF S+ + S EP +CY E++K + + K++R +V++Y + + K Sbjct: 36 QLWAGLLRNRCFFDNNIRMLYNVSGSVSEYYRVDET-----DDIPFICSTNRENGMLRCSNVPKRRVAGADCELTADNVTELVFKE--APHHGCVNWNLYYNTCNASEHNPHNGAINFDNIGYAWIAIFQVITLEGWADIMYYVMDAHSFYNFIYFIFLIIVGSFFMINLCLVVIATQFSETKQRENQLMQEQRARFRSNESTLASLAEPGSCYEEMLKYLAHVCRKLWRHVVRIYGDLCPKRRK 273 HSP 4 Score: 142.124 bits (357), Expect = 4.140e-33 Identity = 150/551 (27.22%), Postives = 267/551 (48.46%), Query Frame = 1 Query: 3865 RQKCQHIVDKKSFDYLVLFFITLNCITLAMERPSIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKFYYCDGPHLQAVKTKNDCLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFHKCQENQXXXXXXXXXXXXXXXXXXXXXHLRAPLY-WENYSKWRRTINSVVTSKYFDLAIAGVIGLNVITMATEF-HMMPQ-VLKTALKVFNYFFTSTFVXXXXXXXXX----XXXXRYISDKWNQLDMMIVILSIAGVVIDEVESNFMPINPTIMRVMRVLRIARVLKLLKMASGIRALLDTVIQALPQVGNXXXXXXXXXXXXXXXXVELF-GRL-ECSDIN--------PCVG-----LGRHAHFENFGMAFLTLFRIATGDNWNGIMKDTL 5451 R + IVD K F+ ++ I +N +++ +E P + L ++N +FT +F EM++K+ + GL Y+ + +NI DG +V IS+ + ++G ++ F +LR FRLLR L+ +R + P L+ + L+ ++ + ++ F IF ILG+ LF KF L+ + + + NFD+L A++ +F + +++ W ++Y G+ + + +A +YF++ + + + N+ V ++VE F E + + + R H LY + + +R V+T K FD + I N IT+A E + P + LKV NY FT FV E +K+V+ G Y+ WN LD +V +SI +++ S I I+RV+R+LR R L+++ A G++ +++T+I +L +GN+ L+ F +F LGV+LF G+ C + C+ + R +F+N G A ++LF +++ D W IM D L Sbjct: 371 RAVLKRIVDSKYFNRGIMIAILINTLSMGVEYHEQPDELTD--VLEISNIVFTSLFVLEMLLKLSACGLF----DYISNPYNIFDGIIVIISVCE-----IVGQADGGFSVLRTFRLLRVLKLVRFL---PALRRQLVVLMKTMDNVATFCMLLMLFIFIFSILGMHLFGCKF----------------TLRLENGDTVSDRKNFDSLLWAIVTVFQILTQEDWNVVLYNGMAST----------SPYAALYFVALMTFGNYVLFNLLVAILVEGFQA-----ESWCLILKRLLEPYKPQWCRDHEDWSLYLFAPQNNFRMRCQKVITHKMFDHIVLFFIFFNCITIALERPDIQPDSTERIFLKVSNYIFTVIFVAEMTVKVVSLGLYAGPGSYLKSSWNVLDGFLVFVSIVDILVSLASSGGNRIL-GILRVLRLLRTLRPLRVISRAPGLKLVVETLITSLRPIGNIVLICCAFFIVFGILGVQLFKGKFYHCEGFDTRNITNKSECLQAKYKWIRRKYNFDNLGQALMSLFVLSSKDGWVNIMYDGL 875 HSP 5 Score: 86.2705 bits (212), Expect = 4.361e-16 Identity = 60/205 (29.27%), Postives = 106/205 (51.71%), Query Frame = 1 Query: 2164 IKTLVNDVKFQRGILIAILINTLSMGIEYHQQPVQLTQTLEFSNIVFSILFLIEMILKLIGEGILGYIKNGFNLFDGIIVVLGVIELCQQG---------GTSGLSILRTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKFCTIENNKRTCDR-KNFDSLLWSIVTVFQILTQEDWNTVL 2748 I TL I I I IN L+M +E+++QP L + L++ N F+++F+IE LKL+ G + K +N D IV+L ++ + + + + I+R R+ R+LKL++ +R L +++ + V L +L FI++ LG+ LFG CT EN R F + + +T+F++ T ++WN ++ Sbjct: 965 IHTLCTSHYLDLFITIIIAINVLTMSMEHYRQPKYLDEGLKYCNYFFTLVFVIEAALKLVAFGFRRFFKERWNQLDLAIVLLSIMGITLEEIDLNASLPINPTIIRIMRVLRIARVLKLLKMATGMRALLDTVVQALPQVGNLGLLFMLLFFIYAALGVELFGKLDCTEENPCEGLSRHATFQNFGMAFLTLFRVSTGDNWNGIM 1169 HSP 6 Score: 72.4034 bits (176), Expect = 6.830e-12 Identity = 67/282 (23.76%), Postives = 137/282 (48.58%), Query Frame = 1 Query: 2155 QQKIKTLVNDVKFQRGILIAILINTLSMGIEYHQ-QPVQLTQT-LEFSNIVFSILFLIEMILKLIGEGILG----YIKNGFNLFDGIIVVLGVIELCQQGGTSG-------LSILRTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKFCTIEN-------NKRTC---------DRKNFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTS----------SWAALYFIALMTFGNYVLFNLLVAILVEGFSSERLDE 2883 + + + ++ F +L I N +++ +E QP + L+ SN +F+++F+ EM +K++ G+ Y+K+ +N+ DG +V + ++++ +SG L +LR R LR L+++ P L+ + +I ++ + + F +F ILG+ LF KF E NK C + NFD+L +++++F + +++ W ++Y+G+ + W LYFI+ + ++ + N+ V ++VE F R D+ Sbjct: 645 RMRCQKVITHKMFDHIVLFFIFFNCITIALERPDIQPDSTERIFLKVSNYIFTVIFVAEMTVKVVSLGLYAGPGSYLKSSWNVLDGFLVFVSIVDILVSLASSGGNRILGILRVLRLLRTLRPLRVISRAPGLKLVVETLITSLRPIGNIVLICCAFFIVFGILGVQLFKGKFYHCEGFDTRNITNKSECLQAKYKWIRRKYNFDNLGQALMSLFVLSSKDGWVNIMYDGLDAVAVDQQPIRNHNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHKCRQDQ 926 HSP 7 Score: 63.5438 bits (153), Expect = 3.739e-9 Identity = 34/117 (29.06%), Postives = 64/117 (54.70%), Query Frame = 1 Query: 337 FHIFHQNKHPRDWCLKIITWPWFEQLSMTIIAVNCITLSMYQPCGDQNCETSKCQIMQAFDYIIFAFFTCEMVIKIIAMG-FLGDLGYFGDTWNRLDMFIVIVGSIEILPSTGNNIG 684 ++F + R C K+IT F+ + + I NCIT+++ +P D ++++ ++ +YI F EM +K++++G + G Y +WN LD F+V V ++IL S ++ G Sbjct: 635 LYLFAPQNNFRMRCQKVITHKMFDHIVLFFIFFNCITIALERP--DIQPDSTERIFLKVSNYIFTVIFVAEMTVKVVSLGLYAGPGSYLKSSWNVLDGFLVFVSIVDILVSLASSGG 749 HSP 8 Score: 54.6842 bits (130), Expect = 1.588e-6 Identity = 31/92 (33.70%), Postives = 52/92 (56.52%), Query Frame = 1 Query: 4444 SQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFH--KCQENQ 4713 S++ N NFDN+G A +A+F + + +GW IMY +DA H+ + IYFI +++ +FF++N+ + V+ F K +ENQ Sbjct: 135 SEHNPHNGAINFDNIGYAWIAIFQVITLEGWADIMYYVMDA----------HSFYNFIYFIFLIIVGSFFMINLCLVVIATQFSETKQRENQ 216 HSP 9 Score: 53.9138 bits (128), Expect = 2.721e-6 Identity = 23/82 (28.05%), Postives = 46/82 (56.10%), Query Frame = 1 Query: 2674 NFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTSSWAALYFIALMTFGNYVLFNLLVAILVEGFSSERLDEQKLLHNYRQSLK 2919 NFD++ ++ + +FQ++T E W ++Y M S + +YFI L+ G++ + NL + ++ FS + E +L+ R + Sbjct: 145 NFDNIGYAWIAIFQVITLEGWADIMYYVMDAHSFYNFIYFIFLIIVGSFFMINLCLVVIATQFSETKQRENQLMQEQRARFR 226 HSP 10 Score: 53.9138 bits (128), Expect = 2.985e-6 Identity = 26/80 (32.50%), Postives = 48/80 (60.00%), Query Frame = 1 Query: 1195 NFDNIGFAWVAIFQVISMESWVDIMYYVQDA----------HSFWDWIYFVALIIIGSFFMINLCLVVIASQFSETKRRE 1404 NFDN+G A +++F + S + WV+IMY DA H+ W +YF++ ++I SFF++N+ + V+ F + ++ + Sbjct: 847 NFDNLGQALMSLFVLSSKDGWVNIMYDGLDAVAVDQQPIRNHNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHKCRQDQ 926
BLAST of Voltage-dependent T-type calcium channel subunit alpha vs. Ensembl Zebrafish
Match: cacna1ia (calcium voltage-gated channel subunit alpha1 Ia [Source:ZFIN;Acc:ZDB-GENE-060503-324]) HSP 1 Score: 631.713 bits (1628), Expect = 0.000e+0 Identity = 387/612 (63.24%), Postives = 486/612 (79.41%), Query Frame = 1 Query: 3832 SLYVFSVDNQFRQKCQHIVDKKSFDYLVLFFITLNCITLAMERPSIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKFYYCDGPHLQAVKTKNDCLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFHKCQENQXXXXXXXXXXXXXXXXXXXXXHLRAPLYWENYSKWRRTINSVVTSKYFDLAIAGVIGLNVITMATEFHMMPQVLKTALKVFNYFFTSTFVXXXXXXXXXXXXXRYISDKWNQLDMMIVILSIAGVVIDEVE-SNFMPINPTIMRVMRVLRIARVLKLLKMASGIRALLDTVIQALPQVGNXXXXXXXXXXXXXXXXVELFGRLECSDINPCVGLGRHAHFENFGMAFLTLFRIATGDNWNGIMKDTLREKCISSEDCQRNCCVSAIIAPIYFVIFXXXXXXXXXXXXXXXXXKHLEESHKMMCDDYELEREVQRDLDE 5664 S+++FS N+FR CQ I+ K FDY+VL FI NCIT+A+ERP I S ERLFLTV+NYIFT IF GEM +KV+S GL IG+QAYL+S WNI+DGFLVF+SL+D+ +++ G +I G+LRV RLLRTLRPLRVISRAPGLKLVV+TL++SL+PIGNIVLICC FFIIFGILGVQLFKGKFYYC G ++ + K+DCL + +W + KYNFDNLGQALM+LFVL+SKDGWV IMY G+DAV V+ QP N+N W L+YFISFLL+V+FFVLNMFVGVVVENFHKC+++QE EE RR KR RR+EKKR+ + Y+ +YS R I+++ TS Y D+ I +I +NV+TM+ E + P L+ ALK NYFFTSTFVLEA+LKL+A G R+ D+WNQLD+ IV+LS+ G+ ++E+E S +PINPTI+R+MRVLRIARVLKLLKMA+G+RALLDTV+QALPQVGNLGLLF LLF+I+AALGVELFG L C++ PC G+ RHA FENFGMAFLTLF+++TGDNWNGIMKDTLRE C + I+P+YFV FVL AQFVL+NVVVAVLMKHL++S+K ++ E++ E++ +L + Sbjct: 1043 SVFLFSPQNKFRLLCQSIIAHKLFDYVVLAFIFSNCITVALERPKILQGSLERLFLTVSNYIFTAIFVGEMTLKVVSMGLYIGEQAYLRSSWNILDGFLVFVSLIDIVVSMAGG--AKILGVLRVLRLLRTLRPLRVISRAPGLKLVVETLITSLKPIGNIVLICCAFFIIFGILGVQLFKGKFYYCLGLDVKNITNKSDCL-LANYKWVHHKYNFDNLGQALMSLFVLASKDGWVNIMYHGLDAVAVDQQPITNNNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHKCRQHQEVEEAKRREEKRQRRMEKKRRKAQKLPYYASYSHVRLMIHTLCTSHYLDIFITFIICVNVVTMSLEHYSQPHSLEIALKYCNYFFTSTFVLEAVLKLIAFGFRRFFKDRWNQLDLAIVLLSVMGITLEEIEISAALPINPTIIRIMRVLRIARVLKLLKMATGMRALLDTVVQALPQVGNLGLLFMLLFFIYAALGVELFGELVCNEDYPCEGMSRHATFENFGMAFLTLFQVSTGDNWNGIMKDTLRECPPGEYTCNPSL---QFISPLYFVSFVLTAQFVLINVVVAVLMKHLDDSNKEAQEEAEMDAEIEMELAQ 1648 HSP 2 Score: 332.798 bits (852), Expect = 3.072e-91 Identity = 216/395 (54.68%), Postives = 276/395 (69.87%), Query Frame = 1 Query: 400 WFEQLSMTIIAVNCITLSMYQPCGDQNCETSKCQIMQAFDYIIFAFFTCEMVIKIIAMGFLGDLGYFGDTWNRLDMFIVIVGSIEILPSTGNNIGLTAIRTIRVLRPLRAINRIPSMRIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQMWQGVLRNRCYLNLNESFRHPGLNLSS-FYQINRTLFLNAVDKDFICSTDKNNGILKCSDIPP------SIMLLSNNSL--QICKQPARPFTDNLPTKHS-CVNWNQYYTDCQPGEKNPYEGAINFDNIGFAWVAIFQVISMESWVDIMYYVQDAHSFWDWIYFVALIIIGSFFMINLCLVVIASQFSETKRRETERMWIERRRFNSSNCSSISKDEPQTCYLEXXXXXXXXXXXXYRRIVKLY 1554 WFE++S+ +I +NC+TL MYQPC + +C + +CQ++QAFD I+ FF EMV+K++A+G G Y GDTWNRLD FIV+ G +E NI +AIRT+RVLRPL+AINR+PSMRILV LLLDTLPMLGNVLLLCFFVFFIFGIIGVQ+W G+LRNRCY N + GL L + +YQ ++ FICS ++NGI+ CSD+P L ++L Q A P + + CVNWNQYYT C G NP++GAINFDNIG+AW+ IFQVI++E WV+IMYYV DAHSF+++IYF+ LIIIGSFFMINLCLVVIA+QFSETK+RE + M +R R+ SS+ + S EP CY E+ +L+ I+ K RR LY Sbjct: 12 WFERISIMVILLNCVTLGMYQPCENIDCTSERCQVLQAFDAFIYIFFALEMVVKMVALGIFGRRCYLGDTWNRLDFFIVMAGMVEYSLDL-QNINFSAIRTVRVLRPLKAINRVPSMRILVNLLLDTLPMLGNVLLLCFFVFFIFGIIGVQLWAGLLRNRCYPEENFTLTS-GLTLPTPYYQPEED-----DERPFICSLAQDNGIMSCSDVPARREGGRECCLDKEDALHRQALGLSAEPLVNGSASAMGLCVNWNQYYTRCHTGHTNPHKGAINFDNIGYAWIVIFQVITLEGWVEIMYYVMDAHSFYNFIYFIFLIIIGSFFMINLCLVVIATQFSETKQREHQLMQEQRARYLSSS-TLASLAEPGDCYEELFQLVCHILRKARRRSAALY 398 HSP 3 Score: 290.426 bits (742), Expect = 2.732e-78 Identity = 163/267 (61.05%), Postives = 198/267 (74.16%), Query Frame = 1 Query: 2095 RRPFNKNQNKTKRKNYLSICQQ-------KIKTLVNDVKFQRGILIAILINTLSMGIEYHQQPVQLTQTLEFSNIVFSILFLIEMILKLIGEGILGYIKNGFNLFDGIIVVLGVIELCQQGGTSGLSILRTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKFC-TIENNKRTCDRKNFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTSSWAALYFIALMTFGNYVLFNLLVAILVEGFSSE 2871 +R + + K++ L C+ K+ +V F RGI+IAILINT+SMGIE+H QP +LT LE NIVF+ +F +EMILKL G Y++N +N+FDGIIV++ V E+ Q GLS+LRTFRLLR++KLVRFMPALR+QL V+++T+DNVATF LL+LFIFIFSILGM +FGCKF E DRKNFDSLLW+IVTVFQILTQEDWN VLYNGM TS AALYF+ALMTFGNYVLFNLLVAILVEGF +E Sbjct: 511 KRSSDSDDTLKKKRTCLGKCKDVWDEIRVKLWGIVESKYFNRGIMIAILINTISMGIEHHNQPDELTNVLEICNIVFTSMFTLEMILKLTAFGFFEYLRNPYNIFDGIIVIISVCEIIGQS-DGGLSVLRTFRLLRVIKLVRFMPALRRQLVVLMKTMDNVATFCMLLMLFIFIFSILGMHIFGCKFSLKTEAGDTVPDRKNFDSLLWAIVTVFQILTQEDWNMVLYNGMASTSPLAALYFVALMTFGNYVLFNLLVAILVEGFQAE 776 HSP 4 Score: 108.997 bits (271), Expect = 6.341e-23 Identity = 72/280 (25.71%), Postives = 137/280 (48.93%), Query Frame = 1 Query: 3856 NQFRQKCQHIVDKKSFDYLVLFFITLNCITLAMERPSIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKFYYCDGPHLQAVKTKNDCLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFH 4695 ++ R K IV+ K F+ ++ I +N I++ +E + P L + N +FT +FT EMI+K+ + G YL++ +NI DG +V IS+ + ++G S+ +LR FRLLR ++ +R + P L+ + L+ ++ + ++ F IF ILG+ +F KF LK + + NFD+L A++ +F + +++ W ++Y G+ + + A +YF++ + + + N+ V ++VE F Sbjct: 535 DEIRVKLWGIVESKYFNRGIMIAILINTISMGIEHHNQPDELTN--VLEICNIVFTSMFTLEMILKLTAFGFF----EYLRNPYNIFDGIIVIISVCE-----IIGQSDGGLSVLRTFRLLRVIKLVRFM---PALRRQLVVLMKTMDNVATFCMLLMLFIFIFSILGMHIFGCKF----------------SLKTEAGDTVPDRKNFDSLLWAIVTVFQILTQEDWNMVLYNGMAST----------SPLAALYFVALMTFGNYVLFNLLVAILVEGFQ 774 HSP 5 Score: 88.5817 bits (218), Expect = 8.586e-17 Identity = 67/266 (25.19%), Postives = 127/266 (47.74%), Query Frame = 1 Query: 2164 IKTLVNDVKFQRGILIAILINTLSMGIEYHQQPVQLTQTLEFSNIVFSILFLIEMILKLIGEGILGYIKNGFNLFDGIIVVLGVIELCQQG---------GTSGLSILRTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKFCTIENNKRTCD----RKNFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTSSW-----------AALYFIALMTFGNYVLFNLLVAILVEGFSSERLDEQK 2889 I TL I I +N ++M +E++ QP L L++ N F+ F++E +LKLI G + K+ +N D IV+L V+ + + + + I+R R+ R+LKL++ +R L +++ + V L +L FI++ LG+ LFG C N C+ F++ + +T+FQ+ T ++WN ++ + + + LYF++ + +VL N++VA+L++ + Q+ Sbjct: 1372 IHTLCTSHYLDIFITFIICVNVVTMSLEHYSQPHSLEIALKYCNYFFTSTFVLEAVLKLIAFGFRRFFKDRWNQLDLAIVLLSVMGITLEEIEISAALPINPTIIRIMRVLRIARVLKLLKMATGMRALLDTVVQALPQVGNLGLLFMLLFFIYAALGVELFGELVC---NEDYPCEGMSRHATFENFGMAFLTLFQVSTGDNWNGIMKDTLRECPPGEYTCNPSLQFISPLYFVSFVLTAQFVLINVVVAVLMKHLDDSNKEAQE 1634 HSP 6 Score: 76.2554 bits (186), Expect = 5.683e-13 Identity = 55/161 (34.16%), Postives = 92/161 (57.14%), Query Frame = 1 Query: 3901 FDYLVLFFITLNCITLAMERP--SIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKG 4377 F+ + + I LNC+TL M +P +I S+ L + I F EM++K+++ G+ G + YL WN +D F+V +++ + + N F +R +R LRPL+ I+R P ++++V LL +L +GN++L+C F IFGI+GVQL+ G Sbjct: 13 FERISIMVILLNCVTLGMYQPCENIDCTSERCQVLQAFDAFIYIFFALEMVVKMVALGIF-GRRCYLGDTWNRLDFFIVMAGMVEYSLDL----QNINFSAIRT---VRVLRPLKAINRVPSMRILVNLLLDTLPMLGNVLLLCFFVFFIFGIIGVQLWAG 165 HSP 7 Score: 70.4774 bits (171), Expect = 2.934e-11 Identity = 65/220 (29.55%), Postives = 113/220 (51.36%), Query Frame = 1 Query: 4807 YSKWRRTINSVVTSKYFDLAIAGVIGLNVITMATEFHMMPQVLKTALKVFNYFFTSTFVXXXXXXXXXXXXXRYISDKWNQLDMMIVILSIAGVVIDEVESNFMPINPTIMRVMRVLRIARVLKLLKMASGIRALLDTVIQALPQVGNXXXXXXXXXXXXXXXXVELFG-----RLECSDINPCVGLGRHAHFENFGMAFLTLFRIATGDNWNGIMKDTL 5451 + + R + +V SKYF+ I I +N I+M E H P L L++ N FTS F LE +LKL A G Y+ + +N D +IVI+S+ +I + + + V+R R+ RV+KL++ +R L +++ + V +L L +IF+ LG+ +FG + E D P +F++ A +T+F+I T ++WN ++ + + Sbjct: 534 WDEIRVKLWGIVESKYFNRGIMIAILINTISMGIEHHNQPDELTNVLEICNIVFTSMFTLEMILKLTAFGFFEYLRNPYNIFDGIIVIISVCE-IIGQSDGG--------LSVLRTFRLLRVIKLVRFMPALRRQLVVLMKTMDNVATFCMLLMLFIFIFSILGMHIFGCKFSLKTEAGDTVP-----DRKNFDSLLWAIVTVFQILTQEDWNMVLYNGM 739 HSP 8 Score: 67.3958 bits (163), Expect = 2.152e-10 Identity = 69/272 (25.37%), Postives = 132/272 (48.53%), Query Frame = 1 Query: 2191 FQRGILIAILINTLSMGIEYHQQPVQLTQTLE-----FSNIVFSILFLIEMILKLIGEGIL----GYIKNGFNLFDGIIVVLGVIELC--QQGGTS---GLSILRTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKF----------------CTIENNKRTCDRKNFDSLLWSIVTVFQILTQEDWNTVLYNGM----------TRTSSWAALYFIALMTFGNYVLFNLLVAILVEGFSSERLDEQ 2886 F +L I N +++ +E +P L +LE SN +F+ +F+ EM LK++ G+ Y+++ +N+ DG +V + +I++ GG L +LR R LR L+++ P L+ + +I ++ + + F IF ILG+ LF KF C + N K + NFD+L +++++F + +++ W ++Y+G+ T + W LYFI+ + ++ + N+ V ++VE F R ++ Sbjct: 1066 FDYVVLAFIFSNCITVALE---RPKILQGSLERLFLTVSNYIFTAIFVGEMTLKVVSMGLYIGEQAYLRSSWNILDGFLVFVSLIDIVVSMAGGAKILGVLRVLRLLRTLRPLRVISRAPGLKLVVETLITSLKPIGNIVLICCAFFIIFGILGVQLFKGKFYYCLGLDVKNITNKSDCLLANYKWVHHKYNFDNLGQALMSLFVLASKDGWVNIMYHGLDAVAVDQQPITNNNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHKCRQHQE 1334 HSP 9 Score: 57.3806 bits (137), Expect = 2.329e-7 Identity = 38/117 (32.48%), Postives = 61/117 (52.14%), Query Frame = 1 Query: 331 TVFHIFHQNKHPRDWCLKIITWPWFEQLSMTIIAVNCITLSMYQPCGDQNCETSKCQIMQAFDYIIFAFFTCEMVIKIIAMG-FLGDLGYFGDTWNRLDMFIVIVGSIEILPSTGNN 678 +VF QNK R C II F+ + + I NCIT+++ +P Q + + + +YI A F EM +K+++MG ++G+ Y +WN LD F+V V I+I+ S Sbjct: 1043 SVFLFSPQNKF-RLLCQSIIAHKLFDYVVLAFIFSNCITVALERPKILQG--SLERLFLTVSNYIFTAIFVGEMTLKVVSMGLYIGEQAYLRSSWNILDGFLVFVSLIDIVVSMAGG 1156 HSP 10 Score: 54.299 bits (129), Expect = 2.197e-6 Identity = 25/80 (31.25%), Postives = 48/80 (60.00%), Query Frame = 1 Query: 1195 NFDNIGFAWVAIFQVISMESWVDIMYYVQDAHSF----------WDWIYFVALIIIGSFFMINLCLVVIASQFSETKRRE 1404 NFDN+G A +++F + S + WV+IMY+ DA + W +YF++ ++I SFF++N+ + V+ F + ++ + Sbjct: 1254 NFDNLGQALMSLFVLASKDGWVNIMYHGLDAVAVDQQPITNNNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHKCRQHQ 1333
BLAST of Voltage-dependent T-type calcium channel subunit alpha vs. Ensembl Zebrafish
Match: cacna1ia (calcium voltage-gated channel subunit alpha1 Ia [Source:ZFIN;Acc:ZDB-GENE-060503-324]) HSP 1 Score: 631.328 bits (1627), Expect = 0.000e+0 Identity = 387/612 (63.24%), Postives = 486/612 (79.41%), Query Frame = 1 Query: 3832 SLYVFSVDNQFRQKCQHIVDKKSFDYLVLFFITLNCITLAMERPSIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKFYYCDGPHLQAVKTKNDCLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFHKCQENQXXXXXXXXXXXXXXXXXXXXXHLRAPLYWENYSKWRRTINSVVTSKYFDLAIAGVIGLNVITMATEFHMMPQVLKTALKVFNYFFTSTFVXXXXXXXXXXXXXRYISDKWNQLDMMIVILSIAGVVIDEVE-SNFMPINPTIMRVMRVLRIARVLKLLKMASGIRALLDTVIQALPQVGNXXXXXXXXXXXXXXXXVELFGRLECSDINPCVGLGRHAHFENFGMAFLTLFRIATGDNWNGIMKDTLREKCISSEDCQRNCCVSAIIAPIYFVIFXXXXXXXXXXXXXXXXXKHLEESHKMMCDDYELEREVQRDLDE 5664 S+++FS N+FR CQ I+ K FDY+VL FI NCIT+A+ERP I S ERLFLTV+NYIFT IF GEM +KV+S GL IG+QAYL+S WNI+DGFLVF+SL+D+ +++ G +I G+LRV RLLRTLRPLRVISRAPGLKLVV+TL++SL+PIGNIVLICC FFIIFGILGVQLFKGKFYYC G ++ + K+DCL + +W + KYNFDNLGQALM+LFVL+SKDGWV IMY G+DAV V+ QP N+N W L+YFISFLL+V+FFVLNMFVGVVVENFHKC+++QE EE RR KR RR+EKKR+ + Y+ +YS R I+++ TS Y D+ I +I +NV+TM+ E + P L+ ALK NYFFTSTFVLEA+LKL+A G R+ D+WNQLD+ IV+LS+ G+ ++E+E S +PINPTI+R+MRVLRIARVLKLLKMA+G+RALLDTV+QALPQVGNLGLLF LLF+I+AALGVELFG L C++ PC G+ RHA FENFGMAFLTLF+++TGDNWNGIMKDTLRE C + I+P+YFV FVL AQFVL+NVVVAVLMKHL++S+K ++ E++ E++ +L + Sbjct: 1043 SVFLFSPQNKFRLLCQSIIAHKLFDYVVLAFIFSNCITVALERPKILQGSLERLFLTVSNYIFTAIFVGEMTLKVVSMGLYIGEQAYLRSSWNILDGFLVFVSLIDIVVSMAGG--AKILGVLRVLRLLRTLRPLRVISRAPGLKLVVETLITSLKPIGNIVLICCAFFIIFGILGVQLFKGKFYYCLGLDVKNITNKSDCL-LANYKWVHHKYNFDNLGQALMSLFVLASKDGWVNIMYHGLDAVAVDQQPITNNNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHKCRQHQEVEEAKRREEKRQRRMEKKRRKAQKLPYYASYSHVRLMIHTLCTSHYLDIFITFIICVNVVTMSLEHYSQPHSLEIALKYCNYFFTSTFVLEAVLKLIAFGFRRFFKDRWNQLDLAIVLLSVMGITLEEIEISAALPINPTIIRIMRVLRIARVLKLLKMATGMRALLDTVVQALPQVGNLGLLFMLLFFIYAALGVELFGELVCNEDYPCEGMSRHATFENFGMAFLTLFQVSTGDNWNGIMKDTLRECPPGEYTCNPSL---QFISPLYFVSFVLTAQFVLINVVVAVLMKHLDDSNKEAQEEAEMDAEIEMELAQ 1648 HSP 2 Score: 332.028 bits (850), Expect = 4.047e-91 Identity = 216/395 (54.68%), Postives = 276/395 (69.87%), Query Frame = 1 Query: 400 WFEQLSMTIIAVNCITLSMYQPCGDQNCETSKCQIMQAFDYIIFAFFTCEMVIKIIAMGFLGDLGYFGDTWNRLDMFIVIVGSIEILPSTGNNIGLTAIRTIRVLRPLRAINRIPSMRIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQMWQGVLRNRCYLNLNESFRHPGLNLSS-FYQINRTLFLNAVDKDFICSTDKNNGILKCSDIPP------SIMLLSNNSL--QICKQPARPFTDNLPTKHS-CVNWNQYYTDCQPGEKNPYEGAINFDNIGFAWVAIFQVISMESWVDIMYYVQDAHSFWDWIYFVALIIIGSFFMINLCLVVIASQFSETKRRETERMWIERRRFNSSNCSSISKDEPQTCYLEXXXXXXXXXXXXYRRIVKLY 1554 WFE++S+ +I +NC+TL MYQPC + +C + +CQ++QAFD I+ FF EMV+K++A+G G Y GDTWNRLD FIV+ G +E NI +AIRT+RVLRPL+AINR+PSMRILV LLLDTLPMLGNVLLLCFFVFFIFGIIGVQ+W G+LRNRCY N + GL L + +YQ ++ FICS ++NGI+ CSD+P L ++L Q A P + + CVNWNQYYT C G NP++GAINFDNIG+AW+ IFQVI++E WV+IMYYV DAHSF+++IYF+ LIIIGSFFMINLCLVVIA+QFSETK+RE + M +R R+ SS+ + S EP CY E+ +L+ I+ K RR LY Sbjct: 12 WFERISIMVILLNCVTLGMYQPCENIDCTSERCQVLQAFDAFIYIFFALEMVVKMVALGIFGRRCYLGDTWNRLDFFIVMAGMVEYSLDL-QNINFSAIRTVRVLRPLKAINRVPSMRILVNLLLDTLPMLGNVLLLCFFVFFIFGIIGVQLWAGLLRNRCYPEENFTLTS-GLTLPTPYYQPEED-----DERPFICSLAQDNGIMSCSDVPARREGGRECCLDKEDALHRQALGLSAEPLVNGSASAMGLCVNWNQYYTRCHTGHTNPHKGAINFDNIGYAWIVIFQVITLEGWVEIMYYVMDAHSFYNFIYFIFLIIIGSFFMINLCLVVIATQFSETKQREHQLMQEQRARYLSSS-TLASLAEPGDCYEELFQLVCHILRKARRRSAALY 398 HSP 3 Score: 290.041 bits (741), Expect = 3.662e-78 Identity = 163/267 (61.05%), Postives = 198/267 (74.16%), Query Frame = 1 Query: 2095 RRPFNKNQNKTKRKNYLSICQQ-------KIKTLVNDVKFQRGILIAILINTLSMGIEYHQQPVQLTQTLEFSNIVFSILFLIEMILKLIGEGILGYIKNGFNLFDGIIVVLGVIELCQQGGTSGLSILRTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKFC-TIENNKRTCDRKNFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTSSWAALYFIALMTFGNYVLFNLLVAILVEGFSSE 2871 +R + + K++ L C+ K+ +V F RGI+IAILINT+SMGIE+H QP +LT LE NIVF+ +F +EMILKL G Y++N +N+FDGIIV++ V E+ Q GLS+LRTFRLLR++KLVRFMPALR+QL V+++T+DNVATF LL+LFIFIFSILGM +FGCKF E DRKNFDSLLW+IVTVFQILTQEDWN VLYNGM TS AALYF+ALMTFGNYVLFNLLVAILVEGF +E Sbjct: 511 KRSSDSDDTLKKKRTCLGKCKDVWDEIRVKLWGIVESKYFNRGIMIAILINTISMGIEHHNQPDELTNVLEICNIVFTSMFTLEMILKLTAFGFFEYLRNPYNIFDGIIVIISVCEIIGQS-DGGLSVLRTFRLLRVIKLVRFMPALRRQLVVLMKTMDNVATFCMLLMLFIFIFSILGMHIFGCKFSLKTEAGDTVPDRKNFDSLLWAIVTVFQILTQEDWNMVLYNGMASTSPLAALYFVALMTFGNYVLFNLLVAILVEGFQAE 776 HSP 4 Score: 108.612 bits (270), Expect = 7.087e-23 Identity = 72/280 (25.71%), Postives = 137/280 (48.93%), Query Frame = 1 Query: 3856 NQFRQKCQHIVDKKSFDYLVLFFITLNCITLAMERPSIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKFYYCDGPHLQAVKTKNDCLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFH 4695 ++ R K IV+ K F+ ++ I +N I++ +E + P L + N +FT +FT EMI+K+ + G YL++ +NI DG +V IS+ + ++G S+ +LR FRLLR ++ +R + P L+ + L+ ++ + ++ F IF ILG+ +F KF LK + + NFD+L A++ +F + +++ W ++Y G+ + + A +YF++ + + + N+ V ++VE F Sbjct: 535 DEIRVKLWGIVESKYFNRGIMIAILINTISMGIEHHNQPDELTN--VLEICNIVFTSMFTLEMILKLTAFGFF----EYLRNPYNIFDGIIVIISVCE-----IIGQSDGGLSVLRTFRLLRVIKLVRFM---PALRRQLVVLMKTMDNVATFCMLLMLFIFIFSILGMHIFGCKF----------------SLKTEAGDTVPDRKNFDSLLWAIVTVFQILTQEDWNMVLYNGMAST----------SPLAALYFVALMTFGNYVLFNLLVAILVEGFQ 774 HSP 5 Score: 88.5817 bits (218), Expect = 8.987e-17 Identity = 67/266 (25.19%), Postives = 127/266 (47.74%), Query Frame = 1 Query: 2164 IKTLVNDVKFQRGILIAILINTLSMGIEYHQQPVQLTQTLEFSNIVFSILFLIEMILKLIGEGILGYIKNGFNLFDGIIVVLGVIELCQQG---------GTSGLSILRTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKFCTIENNKRTCD----RKNFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTSSW-----------AALYFIALMTFGNYVLFNLLVAILVEGFSSERLDEQK 2889 I TL I I +N ++M +E++ QP L L++ N F+ F++E +LKLI G + K+ +N D IV+L V+ + + + + I+R R+ R+LKL++ +R L +++ + V L +L FI++ LG+ LFG C N C+ F++ + +T+FQ+ T ++WN ++ + + + LYF++ + +VL N++VA+L++ + Q+ Sbjct: 1372 IHTLCTSHYLDIFITFIICVNVVTMSLEHYSQPHSLEIALKYCNYFFTSTFVLEAVLKLIAFGFRRFFKDRWNQLDLAIVLLSVMGITLEEIEISAALPINPTIIRIMRVLRIARVLKLLKMATGMRALLDTVVQALPQVGNLGLLFMLLFFIYAALGVELFGELVC---NEDYPCEGMSRHATFENFGMAFLTLFQVSTGDNWNGIMKDTLRECPPGEYTCNPSLQFISPLYFVSFVLTAQFVLINVVVAVLMKHLDDSNKEAQE 1634 HSP 6 Score: 75.8702 bits (185), Expect = 6.055e-13 Identity = 55/161 (34.16%), Postives = 92/161 (57.14%), Query Frame = 1 Query: 3901 FDYLVLFFITLNCITLAMERP--SIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKG 4377 F+ + + I LNC+TL M +P +I S+ L + I F EM++K+++ G+ G + YL WN +D F+V +++ + + N F +R +R LRPL+ I+R P ++++V LL +L +GN++L+C F IFGI+GVQL+ G Sbjct: 13 FERISIMVILLNCVTLGMYQPCENIDCTSERCQVLQAFDAFIYIFFALEMVVKMVALGIF-GRRCYLGDTWNRLDFFIVMAGMVEYSLDL----QNINFSAIRT---VRVLRPLKAINRVPSMRILVNLLLDTLPMLGNVLLLCFFVFFIFGIIGVQLWAG 165 HSP 7 Score: 70.4774 bits (171), Expect = 2.850e-11 Identity = 65/220 (29.55%), Postives = 113/220 (51.36%), Query Frame = 1 Query: 4807 YSKWRRTINSVVTSKYFDLAIAGVIGLNVITMATEFHMMPQVLKTALKVFNYFFTSTFVXXXXXXXXXXXXXRYISDKWNQLDMMIVILSIAGVVIDEVESNFMPINPTIMRVMRVLRIARVLKLLKMASGIRALLDTVIQALPQVGNXXXXXXXXXXXXXXXXVELFG-----RLECSDINPCVGLGRHAHFENFGMAFLTLFRIATGDNWNGIMKDTL 5451 + + R + +V SKYF+ I I +N I+M E H P L L++ N FTS F LE +LKL A G Y+ + +N D +IVI+S+ +I + + + V+R R+ RV+KL++ +R L +++ + V +L L +IF+ LG+ +FG + E D P +F++ A +T+F+I T ++WN ++ + + Sbjct: 534 WDEIRVKLWGIVESKYFNRGIMIAILINTISMGIEHHNQPDELTNVLEICNIVFTSMFTLEMILKLTAFGFFEYLRNPYNIFDGIIVIISVCE-IIGQSDGG--------LSVLRTFRLLRVIKLVRFMPALRRQLVVLMKTMDNVATFCMLLMLFIFIFSILGMHIFGCKFSLKTEAGDTVP-----DRKNFDSLLWAIVTVFQILTQEDWNMVLYNGM 739 HSP 8 Score: 67.781 bits (164), Expect = 1.859e-10 Identity = 69/272 (25.37%), Postives = 132/272 (48.53%), Query Frame = 1 Query: 2191 FQRGILIAILINTLSMGIEYHQQPVQLTQTLE-----FSNIVFSILFLIEMILKLIGEGIL----GYIKNGFNLFDGIIVVLGVIELC--QQGGTS---GLSILRTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKF----------------CTIENNKRTCDRKNFDSLLWSIVTVFQILTQEDWNTVLYNGM----------TRTSSWAALYFIALMTFGNYVLFNLLVAILVEGFSSERLDEQ 2886 F +L I N +++ +E +P L +LE SN +F+ +F+ EM LK++ G+ Y+++ +N+ DG +V + +I++ GG L +LR R LR L+++ P L+ + +I ++ + + F IF ILG+ LF KF C + N K + NFD+L +++++F + +++ W ++Y+G+ T + W LYFI+ + ++ + N+ V ++VE F R ++ Sbjct: 1066 FDYVVLAFIFSNCITVALE---RPKILQGSLERLFLTVSNYIFTAIFVGEMTLKVVSMGLYIGEQAYLRSSWNILDGFLVFVSLIDIVVSMAGGAKILGVLRVLRLLRTLRPLRVISRAPGLKLVVETLITSLKPIGNIVLICCAFFIIFGILGVQLFKGKFYYCLGLDVKNITNKSDCLLANYKWVHHKYNFDNLGQALMSLFVLASKDGWVNIMYHGLDAVAVDQQPITNNNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHKCRQHQE 1334 HSP 9 Score: 57.3806 bits (137), Expect = 2.442e-7 Identity = 38/117 (32.48%), Postives = 61/117 (52.14%), Query Frame = 1 Query: 331 TVFHIFHQNKHPRDWCLKIITWPWFEQLSMTIIAVNCITLSMYQPCGDQNCETSKCQIMQAFDYIIFAFFTCEMVIKIIAMG-FLGDLGYFGDTWNRLDMFIVIVGSIEILPSTGNN 678 +VF QNK R C II F+ + + I NCIT+++ +P Q + + + +YI A F EM +K+++MG ++G+ Y +WN LD F+V V I+I+ S Sbjct: 1043 SVFLFSPQNKF-RLLCQSIIAHKLFDYVVLAFIFSNCITVALERPKILQG--SLERLFLTVSNYIFTAIFVGEMTLKVVSMGLYIGEQAYLRSSWNILDGFLVFVSLIDIVVSMAGG 1156 HSP 10 Score: 54.299 bits (129), Expect = 2.248e-6 Identity = 25/80 (31.25%), Postives = 48/80 (60.00%), Query Frame = 1 Query: 1195 NFDNIGFAWVAIFQVISMESWVDIMYYVQDAHSF----------WDWIYFVALIIIGSFFMINLCLVVIASQFSETKRRE 1404 NFDN+G A +++F + S + WV+IMY+ DA + W +YF++ ++I SFF++N+ + V+ F + ++ + Sbjct: 1254 NFDNLGQALMSLFVLASKDGWVNIMYHGLDAVAVDQQPITNNNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHKCRQHQ 1333
BLAST of Voltage-dependent T-type calcium channel subunit alpha vs. Ensembl Zebrafish
Match: cacna1ia (calcium voltage-gated channel subunit alpha1 Ia [Source:ZFIN;Acc:ZDB-GENE-060503-324]) HSP 1 Score: 631.328 bits (1627), Expect = 0.000e+0 Identity = 387/612 (63.24%), Postives = 486/612 (79.41%), Query Frame = 1 Query: 3832 SLYVFSVDNQFRQKCQHIVDKKSFDYLVLFFITLNCITLAMERPSIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKFYYCDGPHLQAVKTKNDCLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFHKCQENQXXXXXXXXXXXXXXXXXXXXXHLRAPLYWENYSKWRRTINSVVTSKYFDLAIAGVIGLNVITMATEFHMMPQVLKTALKVFNYFFTSTFVXXXXXXXXXXXXXRYISDKWNQLDMMIVILSIAGVVIDEVE-SNFMPINPTIMRVMRVLRIARVLKLLKMASGIRALLDTVIQALPQVGNXXXXXXXXXXXXXXXXVELFGRLECSDINPCVGLGRHAHFENFGMAFLTLFRIATGDNWNGIMKDTLREKCISSEDCQRNCCVSAIIAPIYFVIFXXXXXXXXXXXXXXXXXKHLEESHKMMCDDYELEREVQRDLDE 5664 S+++FS N+FR CQ I+ K FDY+VL FI NCIT+A+ERP I S ERLFLTV+NYIFT IF GEM +KV+S GL IG+QAYL+S WNI+DGFLVF+SL+D+ +++ G +I G+LRV RLLRTLRPLRVISRAPGLKLVV+TL++SL+PIGNIVLICC FFIIFGILGVQLFKGKFYYC G ++ + K+DCL + +W + KYNFDNLGQALM+LFVL+SKDGWV IMY G+DAV V+ QP N+N W L+YFISFLL+V+FFVLNMFVGVVVENFHKC+++QE EE RR KR RR+EKKR+ + Y+ +YS R I+++ TS Y D+ I +I +NV+TM+ E + P L+ ALK NYFFTSTFVLEA+LKL+A G R+ D+WNQLD+ IV+LS+ G+ ++E+E S +PINPTI+R+MRVLRIARVLKLLKMA+G+RALLDTV+QALPQVGNLGLLF LLF+I+AALGVELFG L C++ PC G+ RHA FENFGMAFLTLF+++TGDNWNGIMKDTLRE C + I+P+YFV FVL AQFVL+NVVVAVLMKHL++S+K ++ E++ E++ +L + Sbjct: 1109 SVFLFSPQNKFRLLCQSIIAHKLFDYVVLAFIFSNCITVALERPKILQGSLERLFLTVSNYIFTAIFVGEMTLKVVSMGLYIGEQAYLRSSWNILDGFLVFVSLIDIVVSMAGG--AKILGVLRVLRLLRTLRPLRVISRAPGLKLVVETLITSLKPIGNIVLICCAFFIIFGILGVQLFKGKFYYCLGLDVKNITNKSDCL-LANYKWVHHKYNFDNLGQALMSLFVLASKDGWVNIMYHGLDAVAVDQQPITNNNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHKCRQHQEVEEAKRREEKRQRRMEKKRRKAQKLPYYASYSHVRLMIHTLCTSHYLDIFITFIICVNVVTMSLEHYSQPHSLEIALKYCNYFFTSTFVLEAVLKLIAFGFRRFFKDRWNQLDLAIVLLSVMGITLEEIEISAALPINPTIIRIMRVLRIARVLKLLKMATGMRALLDTVVQALPQVGNLGLLFMLLFFIYAALGVELFGELVCNEDYPCEGMSRHATFENFGMAFLTLFQVSTGDNWNGIMKDTLRECPPGEYTCNPSL---QFISPLYFVSFVLTAQFVLINVVVAVLMKHLDDSNKEAQEEAEMDAEIEMELAQ 1714 HSP 2 Score: 347.051 bits (889), Expect = 1.168e-95 Identity = 223/417 (53.48%), Postives = 288/417 (69.06%), Query Frame = 1 Query: 334 VFHIFHQNKHPRDWCLKIITWPWFEQLSMTIIAVNCITLSMYQPCGDQNCETSKCQIMQAFDYIIFAFFTCEMVIKIIAMGFLGDLGYFGDTWNRLDMFIVIVGSIEILPSTGNNIGLTAIRTIRVLRPLRAINRIPSMRIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQMWQGVLRNRCYLNLNESFRHPGLNLSS-FYQINRTLFLNAVDKDFICSTDKNNGILKCSDIPP------SIMLLSNNSL--QICKQPARPFTDNLPTKHS-CVNWNQYYTDCQPGEKNPYEGAINFDNIGFAWVAIFQVISMESWVDIMYYVQDAHSFWDWIYFVALIIIGSFFMINLCLVVIASQFSETKRRETERMWIERRRFNSSNCSSISKDEPQTCYLEXXXXXXXXXXXXYRRIVKLY 1554 VF Q PR+WC++++ WFE++S+ +I +NC+TL MYQPC + +C + +CQ++QAFD I+ FF EMV+K++A+G G Y GDTWNRLD FIV+ G +E NI +AIRT+RVLRPL+AINR+PSMRILV LLLDTLPMLGNVLLLCFFVFFIFGIIGVQ+W G+LRNRCY N + GL L + +YQ ++ FICS ++NGI+ CSD+P L ++L Q A P + + CVNWNQYYT C G NP++GAINFDNIG+AW+ IFQVI++E WV+IMYYV DAHSF+++IYF+ LIIIGSFFMINLCLVVIA+QFSETK+RE + M +R R+ SS+ + S EP CY E+ +L+ I+ K RR LY Sbjct: 59 VFFCLKQTTCPRNWCIRMV---WFERISIMVILLNCVTLGMYQPCENIDCTSERCQVLQAFDAFIYIFFALEMVVKMVALGIFGRRCYLGDTWNRLDFFIVMAGMVEYSLDL-QNINFSAIRTVRVLRPLKAINRVPSMRILVNLLLDTLPMLGNVLLLCFFVFFIFGIIGVQLWAGLLRNRCYPEENFTLTS-GLTLPTPYYQPEED-----DERPFICSLAQDNGIMSCSDVPARREGGRECCLDKEDALHRQALGLSAEPLVNGSASAMGLCVNWNQYYTRCHTGHTNPHKGAINFDNIGYAWIVIFQVITLEGWVEIMYYVMDAHSFYNFIYFIFLIIIGSFFMINLCLVVIATQFSETKQREHQLMQEQRARYLSSS-TLASLAEPGDCYEELFQLVCHILRKARRRSAALY 464 HSP 3 Score: 290.426 bits (742), Expect = 2.825e-78 Identity = 163/267 (61.05%), Postives = 198/267 (74.16%), Query Frame = 1 Query: 2095 RRPFNKNQNKTKRKNYLSICQQ-------KIKTLVNDVKFQRGILIAILINTLSMGIEYHQQPVQLTQTLEFSNIVFSILFLIEMILKLIGEGILGYIKNGFNLFDGIIVVLGVIELCQQGGTSGLSILRTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKFC-TIENNKRTCDRKNFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTSSWAALYFIALMTFGNYVLFNLLVAILVEGFSSE 2871 +R + + K++ L C+ K+ +V F RGI+IAILINT+SMGIE+H QP +LT LE NIVF+ +F +EMILKL G Y++N +N+FDGIIV++ V E+ Q GLS+LRTFRLLR++KLVRFMPALR+QL V+++T+DNVATF LL+LFIFIFSILGM +FGCKF E DRKNFDSLLW+IVTVFQILTQEDWN VLYNGM TS AALYF+ALMTFGNYVLFNLLVAILVEGF +E Sbjct: 577 KRSSDSDDTLKKKRTCLGKCKDVWDEIRVKLWGIVESKYFNRGIMIAILINTISMGIEHHNQPDELTNVLEICNIVFTSMFTLEMILKLTAFGFFEYLRNPYNIFDGIIVIISVCEIIGQS-DGGLSVLRTFRLLRVIKLVRFMPALRRQLVVLMKTMDNVATFCMLLMLFIFIFSILGMHIFGCKFSLKTEAGDTVPDRKNFDSLLWAIVTVFQILTQEDWNMVLYNGMASTSPLAALYFVALMTFGNYVLFNLLVAILVEGFQAE 842 HSP 4 Score: 108.997 bits (271), Expect = 6.560e-23 Identity = 72/280 (25.71%), Postives = 137/280 (48.93%), Query Frame = 1 Query: 3856 NQFRQKCQHIVDKKSFDYLVLFFITLNCITLAMERPSIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKFYYCDGPHLQAVKTKNDCLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFH 4695 ++ R K IV+ K F+ ++ I +N I++ +E + P L + N +FT +FT EMI+K+ + G YL++ +NI DG +V IS+ + ++G S+ +LR FRLLR ++ +R + P L+ + L+ ++ + ++ F IF ILG+ +F KF LK + + NFD+L A++ +F + +++ W ++Y G+ + + A +YF++ + + + N+ V ++VE F Sbjct: 601 DEIRVKLWGIVESKYFNRGIMIAILINTISMGIEHHNQPDELTN--VLEICNIVFTSMFTLEMILKLTAFGFF----EYLRNPYNIFDGIIVIISVCE-----IIGQSDGGLSVLRTFRLLRVIKLVRFM---PALRRQLVVLMKTMDNVATFCMLLMLFIFIFSILGMHIFGCKF----------------SLKTEAGDTVPDRKNFDSLLWAIVTVFQILTQEDWNMVLYNGMAST----------SPLAALYFVALMTFGNYVLFNLLVAILVEGFQ 840 HSP 5 Score: 88.9669 bits (219), Expect = 7.367e-17 Identity = 67/266 (25.19%), Postives = 127/266 (47.74%), Query Frame = 1 Query: 2164 IKTLVNDVKFQRGILIAILINTLSMGIEYHQQPVQLTQTLEFSNIVFSILFLIEMILKLIGEGILGYIKNGFNLFDGIIVVLGVIELCQQG---------GTSGLSILRTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKFCTIENNKRTCD----RKNFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTSSW-----------AALYFIALMTFGNYVLFNLLVAILVEGFSSERLDEQK 2889 I TL I I +N ++M +E++ QP L L++ N F+ F++E +LKLI G + K+ +N D IV+L V+ + + + + I+R R+ R+LKL++ +R L +++ + V L +L FI++ LG+ LFG C N C+ F++ + +T+FQ+ T ++WN ++ + + + LYF++ + +VL N++VA+L++ + Q+ Sbjct: 1438 IHTLCTSHYLDIFITFIICVNVVTMSLEHYSQPHSLEIALKYCNYFFTSTFVLEAVLKLIAFGFRRFFKDRWNQLDLAIVLLSVMGITLEEIEISAALPINPTIIRIMRVLRIARVLKLLKMATGMRALLDTVVQALPQVGNLGLLFMLLFFIYAALGVELFGELVC---NEDYPCEGMSRHATFENFGMAFLTLFQVSTGDNWNGIMKDTLRECPPGEYTCNPSLQFISPLYFVSFVLTAQFVLINVVVAVLMKHLDDSNKEAQE 1700 HSP 6 Score: 75.8702 bits (185), Expect = 5.959e-13 Identity = 55/161 (34.16%), Postives = 92/161 (57.14%), Query Frame = 1 Query: 3901 FDYLVLFFITLNCITLAMERP--SIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKG 4377 F+ + + I LNC+TL M +P +I S+ L + I F EM++K+++ G+ G + YL WN +D F+V +++ + + N F +R +R LRPL+ I+R P ++++V LL +L +GN++L+C F IFGI+GVQL+ G Sbjct: 79 FERISIMVILLNCVTLGMYQPCENIDCTSERCQVLQAFDAFIYIFFALEMVVKMVALGIF-GRRCYLGDTWNRLDFFIVMAGMVEYSLDL----QNINFSAIRT---VRVLRPLKAINRVPSMRILVNLLLDTLPMLGNVLLLCFFVFFIFGIIGVQLWAG 231 HSP 7 Score: 70.4774 bits (171), Expect = 2.973e-11 Identity = 65/220 (29.55%), Postives = 113/220 (51.36%), Query Frame = 1 Query: 4807 YSKWRRTINSVVTSKYFDLAIAGVIGLNVITMATEFHMMPQVLKTALKVFNYFFTSTFVXXXXXXXXXXXXXRYISDKWNQLDMMIVILSIAGVVIDEVESNFMPINPTIMRVMRVLRIARVLKLLKMASGIRALLDTVIQALPQVGNXXXXXXXXXXXXXXXXVELFG-----RLECSDINPCVGLGRHAHFENFGMAFLTLFRIATGDNWNGIMKDTL 5451 + + R + +V SKYF+ I I +N I+M E H P L L++ N FTS F LE +LKL A G Y+ + +N D +IVI+S+ +I + + + V+R R+ RV+KL++ +R L +++ + V +L L +IF+ LG+ +FG + E D P +F++ A +T+F+I T ++WN ++ + + Sbjct: 600 WDEIRVKLWGIVESKYFNRGIMIAILINTISMGIEHHNQPDELTNVLEICNIVFTSMFTLEMILKLTAFGFFEYLRNPYNIFDGIIVIISVCE-IIGQSDGG--------LSVLRTFRLLRVIKLVRFMPALRRQLVVLMKTMDNVATFCMLLMLFIFIFSILGMHIFGCKFSLKTEAGDTVP-----DRKNFDSLLWAIVTVFQILTQEDWNMVLYNGM 805 HSP 8 Score: 67.781 bits (164), Expect = 2.126e-10 Identity = 69/272 (25.37%), Postives = 132/272 (48.53%), Query Frame = 1 Query: 2191 FQRGILIAILINTLSMGIEYHQQPVQLTQTLE-----FSNIVFSILFLIEMILKLIGEGIL----GYIKNGFNLFDGIIVVLGVIELC--QQGGTS---GLSILRTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKF----------------CTIENNKRTCDRKNFDSLLWSIVTVFQILTQEDWNTVLYNGM----------TRTSSWAALYFIALMTFGNYVLFNLLVAILVEGFSSERLDEQ 2886 F +L I N +++ +E +P L +LE SN +F+ +F+ EM LK++ G+ Y+++ +N+ DG +V + +I++ GG L +LR R LR L+++ P L+ + +I ++ + + F IF ILG+ LF KF C + N K + NFD+L +++++F + +++ W ++Y+G+ T + W LYFI+ + ++ + N+ V ++VE F R ++ Sbjct: 1132 FDYVVLAFIFSNCITVALE---RPKILQGSLERLFLTVSNYIFTAIFVGEMTLKVVSMGLYIGEQAYLRSSWNILDGFLVFVSLIDIVVSMAGGAKILGVLRVLRLLRTLRPLRVISRAPGLKLVVETLITSLKPIGNIVLICCAFFIIFGILGVQLFKGKFYYCLGLDVKNITNKSDCLLANYKWVHHKYNFDNLGQALMSLFVLASKDGWVNIMYHGLDAVAVDQQPITNNNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHKCRQHQE 1400 HSP 9 Score: 57.3806 bits (137), Expect = 2.742e-7 Identity = 38/117 (32.48%), Postives = 61/117 (52.14%), Query Frame = 1 Query: 331 TVFHIFHQNKHPRDWCLKIITWPWFEQLSMTIIAVNCITLSMYQPCGDQNCETSKCQIMQAFDYIIFAFFTCEMVIKIIAMG-FLGDLGYFGDTWNRLDMFIVIVGSIEILPSTGNN 678 +VF QNK R C II F+ + + I NCIT+++ +P Q + + + +YI A F EM +K+++MG ++G+ Y +WN LD F+V V I+I+ S Sbjct: 1109 SVFLFSPQNKF-RLLCQSIIAHKLFDYVVLAFIFSNCITVALERPKILQG--SLERLFLTVSNYIFTAIFVGEMTLKVVSMGLYIGEQAYLRSSWNILDGFLVFVSLIDIVVSMAGG 1222 HSP 10 Score: 54.299 bits (129), Expect = 2.319e-6 Identity = 25/80 (31.25%), Postives = 48/80 (60.00%), Query Frame = 1 Query: 1195 NFDNIGFAWVAIFQVISMESWVDIMYYVQDAHSF----------WDWIYFVALIIIGSFFMINLCLVVIASQFSETKRRE 1404 NFDN+G A +++F + S + WV+IMY+ DA + W +YF++ ++I SFF++N+ + V+ F + ++ + Sbjct: 1320 NFDNLGQALMSLFVLASKDGWVNIMYHGLDAVAVDQQPITNNNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHKCRQHQ 1399
BLAST of Voltage-dependent T-type calcium channel subunit alpha vs. Ensembl Xenopus
Match: efhd1 (EF-hand domain family member D1 [Source:Xenbase;Acc:XB-GENE-5738953]) HSP 1 Score: 645.58 bits (1664), Expect = 0.000e+0 Identity = 403/670 (60.15%), Postives = 509/670 (75.97%), Query Frame = 1 Query: 3739 EDP--DEEDMEAMIC--LSKCCPQPKGIFAKRYYH-SLYVFSVDNQFRQKCQHIVDKKSFDYLVLFFITLNCITLAMERPSIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKFYYCDGPHLQAVKTKNDCLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFHKCQENQXXXXXXXXXXXXXXXXXXXXXHLRAPLYWENYSKWRRTINSVVTSKYFDLAIAGVIGLNVITMATEFHMMPQVLKTALKVFNYFFTSTFVXXXXXXXXXXXXXRYISDKWNQLDMMIVILSIAGVVIDEVESNF-MPINPTIMRVMRVLRIARVLKLLKMASGIRALLDTVIQALPQVGNXXXXXXXXXXXXXXXXVELFGRLECSDINPCVGLGRHAHFENFGMAFLTLFRIATGDNWNGIMKDTLREKCISSEDCQRNCCVS-AIIAPIYFVIFXXXXXXXXXXXXXXXXXKHLEESHKMMCDDYELEREVQRDLDEEAKELAREKQLKDEENNENTL 5727 EDP E+D+E C + K K + K + SLY+FS NQFR CQ ++ K FD++VL FI LNCIT+A+ERP I P+S ER+FL+V+NYIFT IF EM IKV++ G + G+ YL+S WN++DG LVF+S++D+ +++ +I G+LRV RLLRTLRPLRVISRAPGLKLVV+TL+SSLRPIGNIVLICC FFIIFGILGVQLFKGKFYYC+G + + +++C + ++ +W +KYNFDNLGQALM+LFVLSSKDGWV IMY G+DAV ++QP +NHN W L+YFISFLL+V+FFVLNMFVGVVVENFHKC+++QE EE RR KR RRLEKKR+ + Y+ YS R I+++ TS Y DL I +I +NVITM+ E + P+ L ALK NY FT FV EAL KLVA G R+ D+WNQLD+ IV+LSI G+ ++E+E N +PINPTI+R+MRVLRIARVLKLLKMA+G+RALLDTV+QALPQVGNLGLLF LLF+I+AALGVELFG+L C++ NPC GL RHA FENFGMAFLTLFR++TGDNWNGIMKDTLRE C S + +NC +I+P+YFV FVL+AQFVLVNVVVAVLMKHLEES+K +D E++ E++ ++ + + Q +D + N L Sbjct: 1210 EDPLEYEDDIEDSYCFRIRKMLEPYKPTWCKTHEDWSLYMFSPQNQFRMMCQKVIAHKMFDHVVLVFIFLNCITIALERPDIDPNSLERIFLSVSNYIFTAIFVLEMAIKVVALGFVSGENTYLQSSWNVLDGILVFVSIIDIVVSLASAGGAKILGVLRVLRLLRTLRPLRVISRAPGLKLVVETLISSLRPIGNIVLICCAFFIIFGILGVQLFKGKFYYCEGLETRNITNRSECTR-ARYKWVRRKYNFDNLGQALMSLFVLSSKDGWVNIMYDGLDAVATDVQPVKNHNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHKCRQHQEAEEARRREEKRLRRLEKKRRKAQRRPYYAEYSPARLYIHTMCTSHYLDLFITCIICINVITMSMEHYNQPKSLDEALKYCNYVFTIVFVFEALFKLVAFGFRRFFKDRWNQLDLAIVLLSIMGITLEEIEINASLPINPTIIRIMRVLRIARVLKLLKMATGMRALLDTVVQALPQVGNLGLLFMLLFFIYAALGVELFGKLVCNEENPCEGLSRHATFENFGMAFLTLFRVSTGDNWNGIMKDTLRE-CNSDD---KNCLTYLPVISPVYFVTFVLIAQFVLVNVVVAVLMKHLEESNKEAKEDAEMDAEIEMEMSRDG-----DFQRRDGSGSRNLL 1869 HSP 2 Score: 407.142 bits (1045), Expect = 4.588e-114 Identity = 233/445 (52.36%), Postives = 311/445 (69.89%), Query Frame = 1 Query: 298 NESLIYHGFYATVFHIFHQNKHPRDWCLKIITWPWFEQLSMTIIAVNCITLSMYQPCGDQNCETSKCQIMQAFDYIIFAFFTCEMVIKIIAMGFLGDLGYFGDTWNRLDMFIVIVGSIEILPSTGNNIGLTAIRTIRVLRPLRAINRIPSMRIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQMWQGVLRNRCYLNLNESFRHPGLNLSSFYQINRTLFLNAVDKDFICSTDKNNGILKCSDIPPSIMLLSNNSLQICKQPARPFTDNLPTKHSCVNWNQYYTDCQPGEKNPYEGAINFDNIGFAWVAIFQVISMESWVDIMYYVQDAHSFWDWIYFVALIIIGSFFMINLCLVVIASQFSETKRRETERMWIERRRFNSSNCSSISKDEPQTCYLEXXXXXXXXXXXXYRRIVKLYNQIQIRHSKTAQGNYQNKLKRQRKHC 1632 E + Y TVF Q PR+WCL+++ P + SM +I +NC+TL M+QPC D NC + +C I++AFD IFAFF EMVIK++A+G G Y GDTWN LD FIV+ G +E G+N+ L+AIRT+RVLRPLRAINR+PSMRILV LLLDTLPMLGNVLLLCFFVFFIFGI+GVQ+W G+LRNRC+++ N + L +YQ++ +A D +ICS++++NG+LKC DIPP + + + + P+++SCVN NQYY C+PGE NP++GAINFDNIG+AW+AIFQVI++E WVDIMYYV DAHSF+++IYF+ LII+GSFFMINLCLVVIA+QFSETK+RE + M +R R+ S++ + S EP +CY E++K I I K+ RR ++LYN Q + K Q N + + + C Sbjct: 63 GEQVPYPALAPTVFFCLSQTTRPRNWCLRLVCNP-YPLHSMLVILLNCVTLGMFQPCEDTNCMSERCNILEAFDGFIFAFFAVEMVIKMVALGIFGQKCYLGDTWNWLDFFIVMAGMLE-YSLDGHNVSLSAIRTVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAGLLRNRCFMDTNFVMSYNFTPLRPYYQVD-----DAEDNPYICSSNRDNGMLKCQDIPPKM------------DCSHVYYSDFPSRNSCVNINQYYNVCKPGEFNPHKGAINFDNIGYAWIAIFQVITLEGWVDIMYYVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQRENQLMQEQRARYLSNDSTIASFSEPGSCYEELLKYICHIFRKVKRRTLRLYNNWQNKRRKKVQPNSNTNSQGRHRKC 488 HSP 3 Score: 344.739 bits (883), Expect = 1.094e-94 Identity = 195/319 (61.13%), Postives = 238/319 (74.61%), Query Frame = 1 Query: 2161 KIKTLVNDVKFQRGILIAILINTLSMGIEYHQQPVQLTQTLEFSNIVFSILFLIEMILKLIGEGILGYIKNGFNLFDGIIVVLGVIELCQQGGTSGLSILRTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKFC-TIENNKRTCDRKNFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTSSWAALYFIALMTFGNYVLFNLLVAILVEGFSSE------RLDEQKLLHNYRQSLKKRRANNKQLRIMQHQSENLVLLTNSIQKDQTGENQKISSQPPVIIHTAATPMPTPRSSP 3096 ++K +V+ F RGI+IAILINTLSMGIEYH+QP +LT LE SNIVF+ +F +EM+LKL+ GI YIKN +N+FDGIIVV+ V E+ Q GLS+LRTFRLLR+LKLVRFMPALR+QL V+++T+DNVATF LL+LFIFIFSILGM LFGCKF T + + DRKNFDSLLW+IVTVFQILTQEDWN VLYNGM TSSWAALYF+ALMTFGNYVLFNLLVAILVEGF +E +E K N+ + L+K K+LR + + +L + N + + S PP+I+ TAATPMPTP+SSP Sbjct: 752 RLKRIVDSKYFNRGIMIAILINTLSMGIEYHEQPEELTNALEISNIVFTSMFALEMLLKLLAFGIFQYIKNPYNIFDGIIVVISVWEIIGQS-DGGLSVLRTFRLLRVLKLVRFMPALRRQLVVLVKTMDNVATFCMLLMLFIFIFSILGMHLFGCKFTWTADTGETVKDRKNFDSLLWAIVTVFQILTQEDWNMVLYNGMASTSSWAALYFVALMTFGNYVLFNLLVAILVEGFQAEGDATRSDTEEDKASGNFDEDLEKL----KELRAAELKMYSLAVTPNG------HLDPRSSMPPPIIMRTAATPMPTPKSSP 1059 HSP 4 Score: 116.316 bits (290), Expect = 4.630e-25 Identity = 73/285 (25.61%), Postives = 141/285 (49.47%), Query Frame = 1 Query: 3841 VFSVDNQFRQKCQHIVDKKSFDYLVLFFITLNCITLAMERPSIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKFYYCDGPHLQAVKTKNDCLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFH 4695 V+ + +F + + IVD K F+ ++ I +N +++ +E P L ++N +FT +F EM++K+L+ G+ Y+K+ +NI DG +V IS+ + ++G S+ +LR FRLLR L+ +R + P L+ + L+ ++ + ++ F IF ILG+ LF KF + E + NFD+L A++ +F + +++ W ++Y G+ + + WA +YF++ + + + N+ V ++VE F Sbjct: 742 VYLLWEEFTVRLKRIVDSKYFNRGIMIAILINTLSMGIEYHEQPEELTNAL--EISNIVFTSMFALEMLLKLLAFGIF----QYIKNPYNIFDGIIVVISVWE-----IIGQSDGGLSVLRTFRLLRVLKLVRFM---PALRRQLVVLVKTMDNVATFCMLLMLFIFIFSILGMHLFGCKFTW----------------TADTGETVKDRKNFDSLLWAIVTVFQILTQEDWNMVLYNGMAST----------SSWAALYFVALMTFGNYVLFNLLVAILVEGFQ 986 HSP 5 Score: 106.686 bits (265), Expect = 4.146e-22 Identity = 99/332 (29.82%), Postives = 157/332 (47.29%), Query Frame = 1 Query: 3916 LFFITLNCITLAMERPSIPPHS-KER--LFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKG---------------------KFYYC-----DGPHL------------QAVKTKNDCLKYSQNEWK--------NQKY---------------NFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFH--KCQENQ 4713 + I LNC+TL M +P + ER + +IF F EM+IK+++ G+ G + YL WN +D F+V +L+ + GH+ + I R +R LRPLR I+R P ++++V LL +L +GN++L+C F IFGI+GVQL+ G + YY D P++ Q + K DC +++ NQ Y NFDN+G A +A+F + + +GWV IMY +DA H+ + IYFI +++ +FF++N+ + V+ F K +ENQ Sbjct: 102 MLVILLNCVTLGMFQPCEDTNCMSERCNILEAFDGFIFAF-FAVEMVIKMVALGIF-GQKCYLGDTWNWLDFFIVMAGMLEYSLD---GHNVSLSAI----RTVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAGLLRNRCFMDTNFVMSYNFTPLRPYYQVDDAEDNPYICSSNRDNGMLKCQDIPPKMDCSHVYYSDFPSRNSCVNINQYYNVCKPGEFNPHKGAINFDNIGYAWIAIFQVITLEGWVDIMYYVMDA----------HSFYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQRENQ 414 HSP 6 Score: 86.2705 bits (212), Expect = 5.863e-16 Identity = 55/201 (27.36%), Postives = 106/201 (52.74%), Query Frame = 1 Query: 2203 ILIAILINTLSMGIEYHQQPVQLTQTLEFSNIVFSILFLIEMILKLIGEGILGYIKNGFNLFDGIIVVLGVIELCQQG---------GTSGLSILRTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKFCTIENNKRTCDR-KNFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTSS 2775 I I IN ++M +E++ QP L + L++ N VF+I+F+ E + KL+ G + K+ +N D IV+L ++ + + + + I+R R+ R+LKL++ +R L +++ + V L +L FI++ LG+ LFG C EN R F++ + +T+F++ T ++WN ++ + + +S Sbjct: 1590 ITCIICINVITMSMEHYNQPKSLDEALKYCNYVFTIVFVFEALFKLVAFGFRRFFKDRWNQLDLAIVLLSIMGITLEEIEINASLPINPTIIRIMRVLRIARVLKLLKMATGMRALLDTVVQALPQVGNLGLLFMLLFFIYAALGVELFGKLVCNEENPCEGLSRHATFENFGMAFLTLFRVSTGDNWNGIMKDTLRECNS 1790 HSP 7 Score: 76.6406 bits (187), Expect = 5.930e-13 Identity = 67/216 (31.02%), Postives = 117/216 (54.17%), Query Frame = 1 Query: 4792 LYWENYSKWRRTINSVVTSKYFDLAIAGVIGLNVITMATEFHMMPQVLKTALKVFNYFFTSTFVXXXXXXXXXXXXXRYISDKWNQLDMMIVILSIAGVVIDEVESNFMPINPTIMRVMRVLRIARVLKLLKMASGIRALLDTVIQALPQVGNXXXXXXXXXXXXXXXXVELFGRLECSDINPCVGLGRHAHFENFGMAFLTLFRIATGDNWNGIM 5439 L WE ++ + +V SKYF+ I I +N ++M E+H P+ L AL++ N FTS F LE LLKL+A G+ +YI + +N D +IV++S+ +I + + + V+R R+ RVLKL++ +R L +++ + V +L L +IF+ LG+ LFG + + +F++ A +T+F+I T ++WN ++ Sbjct: 744 LLWEEFTV---RLKRIVDSKYFNRGIMIAILINTLSMGIEYHEQPEELTNALEISNIVFTSMFALEMLLKLLAFGIFQYIKNPYNIFDGIIVVISVWE-IIGQSDGG--------LSVLRTFRLLRVLKLVRFMPALRRQLVVLVKTMDNVATFCMLLMLFIFIFSILGMHLFGCKFTWTADTGETVKDRKNFDSLLWAIVTVFQILTQEDWNMVL 947 HSP 8 Score: 74.3294 bits (181), Expect = 2.904e-12 Identity = 64/281 (22.78%), Postives = 133/281 (47.33%), Query Frame = 1 Query: 2149 ICQQKIKTLVNDVKFQRGILIAILINTLSMGIEYHQ-QPVQLTQT-LEFSNIVFSILFLIEMILKLIGEGILG----YIKNGFNLFDGIIVVLGVIELCQQGGTSGLSILRTFRLLRILKL-------VRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKFCTIEN-------NKRTCDRK---------NFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTSS----------WAALYFIALMTFGNYVLFNLLVAILVEGFSSER 2874 +CQ+ I + F +L+ I +N +++ +E P L + L SN +F+ +F++EM +K++ G + Y+++ +N+ DGI+V + +I++ ++G + + + L + P L+ + +I ++ + + F IF ILG+ LF KF E N+ C R NFD+L +++++F + +++ W ++Y+G+ ++ W LYFI+ + ++ + N+ V ++VE F R Sbjct: 1259 MCQKVIAHKM----FDHVVLVFIFLNCITIALERPDIDPNSLERIFLSVSNYIFTAIFVLEMAIKVVALGFVSGENTYLQSSWNVLDGILVFVSIIDIVVSLASAGGAKILGVLRVLRLLRTLRPLRVISRAPGLKLVVETLISSLRPIGNIVLICCAFFIIFGILGVQLFKGKFYYCEGLETRNITNRSECTRARYKWVRRKYNFDNLGQALMSLFVLSSKDGWVNIMYDGLDAVATDVQPVKNHNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHKCR 1535 HSP 9 Score: 63.1586 bits (152), Expect = 6.571e-9 Identity = 37/117 (31.62%), Postives = 62/117 (52.99%), Query Frame = 1 Query: 337 FHIFHQNKHPRDWCLKIITWPWFEQLSMTIIAVNCITLSMYQPCGDQNCETSKCQIMQAFDYIIFAFFTCEMVIKIIAMGFL-GDLGYFGDTWNRLDMFIVIVGSIEILPSTGNNIG 684 ++F R C K+I F+ + + I +NCIT+++ +P D N + + + +YI A F EM IK++A+GF+ G+ Y +WN LD +V V I+I+ S + G Sbjct: 1247 LYMFSPQNQFRMMCQKVIAHKMFDHVVLVFIFLNCITIALERPDIDPN--SLERIFLSVSNYIFTAIFVLEMAIKVVALGFVSGENTYLQSSWNVLDGILVFVSIIDIVVSLASAGG 1361 HSP 10 Score: 54.6842 bits (130), Expect = 2.260e-6 Identity = 26/80 (32.50%), Postives = 48/80 (60.00%), Query Frame = 1 Query: 1195 NFDNIGFAWVAIFQVISMESWVDIMYYVQDA----------HSFWDWIYFVALIIIGSFFMINLCLVVIASQFSETKRRE 1404 NFDN+G A +++F + S + WV+IMY DA H+ W +YF++ ++I SFF++N+ + V+ F + ++ + Sbjct: 1459 NFDNLGQALMSLFVLSSKDGWVNIMYDGLDAVATDVQPVKNHNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHKCRQHQ 1538 HSP 11 Score: 53.9138 bits (128), Expect = 4.070e-6 Identity = 24/75 (32.00%), Postives = 44/75 (58.67%), Query Frame = 1 Query: 1195 NFDNIGFAWVAIFQVISMESWVDIMYYVQDAHSFWDWIYFVALIIIGSFFMINLCLVVIASQF---SETKRRETE 1410 NFD++ +A V +FQ+++ E W ++Y + S W +YFVAL+ G++ + NL + ++ F + R +TE Sbjct: 923 NFDSLLWAIVTVFQILTQEDWNMVLYNGMASTSSWAALYFVALMTFGNYVLFNLLVAILVEGFQAEGDATRSDTE 997 HSP 12 Score: 53.5286 bits (127), Expect = 6.041e-6 Identity = 23/78 (29.49%), Postives = 45/78 (57.69%), Query Frame = 1 Query: 2674 NFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTSSWAALYFIALMTFGNYVLFNLLVAILVEGFSSERLDEQKLLHNYR 2907 NFD++ ++ + +FQ++T E W ++Y M S + +YFI L+ G++ + NL + ++ FS + E +L+ R Sbjct: 343 NFDNIGYAWIAIFQVITLEGWVDIMYYVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQRENQLMQEQR 420
BLAST of Voltage-dependent T-type calcium channel subunit alpha vs. Ensembl Xenopus
Match: efhd1 (EF-hand domain family member D1 [Source:Xenbase;Acc:XB-GENE-5738953]) HSP 1 Score: 642.884 bits (1657), Expect = 0.000e+0 Identity = 389/611 (63.67%), Postives = 487/611 (79.71%), Query Frame = 1 Query: 3832 SLYVFSVDNQFRQKCQHIVDKKSFDYLVLFFITLNCITLAMERPSIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKFYYCDGPHLQAVKTKNDCLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFHKCQENQXXXXXXXXXXXXXXXXXXXXXHLRAPLYWENYSKWRRTINSVVTSKYFDLAIAGVIGLNVITMATEFHMMPQVLKTALKVFNYFFTSTFVXXXXXXXXXXXXXRYISDKWNQLDMMIVILSIAGVVIDEVESNF-MPINPTIMRVMRVLRIARVLKLLKMASGIRALLDTVIQALPQVGNXXXXXXXXXXXXXXXXVELFGRLECSDINPCVGLGRHAHFENFGMAFLTLFRIATGDNWNGIMKDTLREKCISSEDCQRNCCVS-AIIAPIYFVIFXXXXXXXXXXXXXXXXXKHLEESHKMMCDDYELEREVQRDL 5658 SLY+FS NQFR CQ ++ K FD++VL FI LNCIT+A+ERP I P+S ER+FL+V+NYIFT IF EM IKV++ G + G+ YL+S WN++DG LVF+S++D+ +++ +I G+LRV RLLRTLRPLRVISRAPGLKLVV+TL+SSLRPIGNIVLICC FFIIFGILGVQLFKGKFYYC+G + + +++C + ++ +W +KYNFDNLGQALM+LFVLSSKDGWV IMY G+DAV ++QP +NHN W L+YFISFLL+V+FFVLNMFVGVVVENFHKC+++QE EE RR KR RRLEKKR+ + Y+ YS R I+++ TS Y DL I +I +NVITM+ E + P+ L ALK NY FT FV EAL KLVA G R+ D+WNQLD+ IV+LSI G+ ++E+E N +PINPTI+R+MRVLRIARVLKLLKMA+G+RALLDTV+QALPQVGNLGLLF LLF+I+AALGVELFG+L C++ NPC GL RHA FENFGMAFLTLFR++TGDNWNGIMKDTLRE +S+D +NC +I+P+YFV FVL+AQFVLVNVVVAVLMKHLEES+K +D E++ E++ ++ Sbjct: 1155 SLYMFSPQNQFRMMCQKVIAHKMFDHVVLVFIFLNCITIALERPDIDPNSLERIFLSVSNYIFTAIFVLEMAIKVVALGFVSGENTYLQSSWNVLDGILVFVSIIDIVVSLASAGGAKILGVLRVLRLLRTLRPLRVISRAPGLKLVVETLISSLRPIGNIVLICCAFFIIFGILGVQLFKGKFYYCEGLETRNITNRSECTR-ARYKWVRRKYNFDNLGQALMSLFVLSSKDGWVNIMYDGLDAVATDVQPVKNHNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHKCRQHQEAEEARRREEKRLRRLEKKRRKAQRRPYYAEYSPARLYIHTMCTSHYLDLFITCIICINVITMSMEHYNQPKSLDEALKYCNYVFTIVFVFEALFKLVAFGFRRFFKDRWNQLDLAIVLLSIMGITLEEIEINASLPINPTIIRIMRVLRIARVLKLLKMATGMRALLDTVVQALPQVGNLGLLFMLLFFIYAALGVELFGKLVCNEENPCEGLSRHATFENFGMAFLTLFRVSTGDNWNGIMKDTLRE--CNSDD--KNCLTYLPVISPVYFVTFVLIAQFVLVNVVVAVLMKHLEESNKEAKEDAEMDAEIEMEM 1760 HSP 2 Score: 404.831 bits (1039), Expect = 1.783e-113 Identity = 236/456 (51.75%), Postives = 313/456 (68.64%), Query Frame = 1 Query: 265 QQETDGTPINPNESLIYHGFYATVFHIFHQNKHPRDWCLKIITWPWFEQLSMTIIAVNCITLSMYQPCGDQNCETSKCQIMQAFDYIIFAFFTCEMVIKIIAMGFLGDLGYFGDTWNRLDMFIVIVGSIEILPSTGNNIGLTAIRTIRVLRPLRAINRIPSMRIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQMWQGVLRNRCYLNLNESFRHPGLNLSSFYQINRTLFLNAVDKDFICSTDKNNGILKCSDIPPSIMLLSNNSLQICKQPARPFTDNLPTKHSCVNWNQYYTDCQPGEKNPYEGAINFDNIGFAWVAIFQVISMESWVDIMYYVQDAHSFWDWIYFVALIIIGSFFMINLCLVVIASQFSETKRRETERMWIERRRFNSSNCSSISKDEPQTCYLEXXXXXXXXXXXXYRRIVKLYNQIQIRHSKTAQGNYQNKLKRQRKHC 1632 Q G E + Y TVF Q PR+WCL+++ P + SM +I +NC+TL M+QPC D NC + +C I++AFD IFAFF EMVIK++A+G G Y GDTWN LD FIV+ G +E G+N+ L+AIRT+RVLRPLRAINR+PSMRILV LLLDTLPMLGNVLLLCFFVFFIFGI+GVQ+W G+LRNRC+++ N F P +YQ++ +A D +ICS++++NG+LKC DIPP + + + + P+++SCVN NQYY C+PGE NP++GAINFDNIG+AW+AIFQVI++E WVDIMYYV DAHSF+++IYF+ LII+GSFFMINLCLVVIA+QFSETK+RE + M +R R+ S++ + S EP +CY E++K I I K+ RR ++LYN Q + K Q N + + + C Sbjct: 22 QGREQGMGSEEGEQVPYPALAPTVFFCLSQTTRPRNWCLRLVCNP-YPLHSMLVILLNCVTLGMFQPCEDTNCMSERCNILEAFDGFIFAFFAVEMVIKMVALGIFGQKCYLGDTWNWLDFFIVMAGMLE-YSLDGHNVSLSAIRTVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAGLLRNRCFMDTN--FVMP------YYQVD-----DAEDNPYICSSNRDNGMLKCQDIPPKM------------DCSHVYYSDFPSRNSCVNINQYYNVCKPGEFNPHKGAINFDNIGYAWIAIFQVITLEGWVDIMYYVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQRENQLMQEQRARYLSNDSTIASFSEPGSCYEELLKYICHIFRKVKRRTLRLYNNWQNKRRKKVQPNSNTNSQGRHRKC 450 HSP 3 Score: 334.724 bits (857), Expect = 1.155e-91 Identity = 188/313 (60.06%), Postives = 231/313 (73.80%), Query Frame = 1 Query: 2161 KIKTLVNDVKFQRGILIAILINTLSMGIEYHQQPVQLTQTLEFSNIVFSILFLIEMILKLIGEGILGYIKNGFNLFDGIIVVLGVIELCQQGGTSGLSILRTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKFC-TIENNKRTCDRKNFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTSSWAALYFIALMTFGNYVLFNLLVAILVEGFSSERLDEQKLLHNYRQSLKKRRANNKQLRIMQHQSENLVLLTNSIQKDQTGENQKISSQPPVIIHTAATPMPTPRSSP 3096 ++K +V+ F RGI+IAILINTLSMGIEYH+QP +LT LE SNIVF+ +F +EM+LKL+ GI YIKN +N+FDGIIVV+ V E+ Q GLS+LRTFRLLR+LKLVRFMPALR+QL V+++T+DNVATF LL+LFIFIFSILGM LFGCKF T + + DRKNFDSLLW+IVTVFQILTQEDWN VLYNGM TSSWAALYF+ALMTFGNYVLFNLLVAILVEGF +E R++ ++ + + + +L + N + + S PP+I+ TAATPMPTP+SSP Sbjct: 689 RLKRIVDSKYFNRGIMIAILINTLSMGIEYHEQPEELTNALEISNIVFTSMFALEMLLKLLAFGIFQYIKNPYNIFDGIIVVISVWEIIGQS-DGGLSVLRTFRLLRVLKLVRFMPALRRQLVVLVKTMDNVATFCMLLMLFIFIFSILGMHLFGCKFTWTADTGETVKDRKNFDSLLWAIVTVFQILTQEDWNMVLYNGMASTSSWAALYFVALMTFGNYVLFNLLVAILVEGFQAEG--------------DATRSDTEEDKASELKMYSLAVTPNG------HLDPRSSMPPPIIMRTAATPMPTPKSSP 980 HSP 4 Score: 115.546 bits (288), Expect = 7.976e-25 Identity = 73/285 (25.61%), Postives = 141/285 (49.47%), Query Frame = 1 Query: 3841 VFSVDNQFRQKCQHIVDKKSFDYLVLFFITLNCITLAMERPSIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKFYYCDGPHLQAVKTKNDCLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFH 4695 V+ + +F + + IVD K F+ ++ I +N +++ +E P L ++N +FT +F EM++K+L+ G+ Y+K+ +NI DG +V IS+ + ++G S+ +LR FRLLR L+ +R + P L+ + L+ ++ + ++ F IF ILG+ LF KF + E + NFD+L A++ +F + +++ W ++Y G+ + + WA +YF++ + + + N+ V ++VE F Sbjct: 679 VYLLWEEFTVRLKRIVDSKYFNRGIMIAILINTLSMGIEYHEQPEELTNAL--EISNIVFTSMFALEMLLKLLAFGIF----QYIKNPYNIFDGIIVVISVWE-----IIGQSDGGLSVLRTFRLLRVLKLVRFM---PALRRQLVVLVKTMDNVATFCMLLMLFIFIFSILGMHLFGCKFTW----------------TADTGETVKDRKNFDSLLWAIVTVFQILTQEDWNMVLYNGMAST----------SSWAALYFVALMTFGNYVLFNLLVAILVEGFQ 923 HSP 5 Score: 108.612 bits (270), Expect = 1.008e-22 Identity = 99/324 (30.56%), Postives = 156/324 (48.15%), Query Frame = 1 Query: 3916 LFFITLNCITLAMERPSIPPHS-KER--LFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKF-------------YYC-----DGPHL------------QAVKTKNDCLKYSQNEWK--------NQKY---------------NFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFH--KCQENQ 4713 + I LNC+TL M +P + ER + +IF F EM+IK+++ G+ G + YL WN +D F+V +L+ + GH+ + I R +R LRPLR I+R P ++++V LL +L +GN++L+C F IFGI+GVQL+ G YY D P++ Q + K DC +++ NQ Y NFDN+G A +A+F + + +GWV IMY +DA H+ + IYFI +++ +FF++N+ + V+ F K +ENQ Sbjct: 72 MLVILLNCVTLGMFQPCEDTNCMSERCNILEAFDGFIFAF-FAVEMVIKMVALGIF-GQKCYLGDTWNWLDFFIVMAGMLEYSLD---GHNVSLSAI----RTVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAGLLRNRCFMDTNFVMPYYQVDDAEDNPYICSSNRDNGMLKCQDIPPKMDCSHVYYSDFPSRNSCVNINQYYNVCKPGEFNPHKGAINFDNIGYAWIAIFQVITLEGWVDIMYYVMDA----------HSFYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQRENQ 376 HSP 6 Score: 85.5001 bits (210), Expect = 9.910e-16 Identity = 55/201 (27.36%), Postives = 106/201 (52.74%), Query Frame = 1 Query: 2203 ILIAILINTLSMGIEYHQQPVQLTQTLEFSNIVFSILFLIEMILKLIGEGILGYIKNGFNLFDGIIVVLGVIELCQQG---------GTSGLSILRTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKFCTIENNKRTCDR-KNFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTSS 2775 I I IN ++M +E++ QP L + L++ N VF+I+F+ E + KL+ G + K+ +N D IV+L ++ + + + + I+R R+ R+LKL++ +R L +++ + V L +L FI++ LG+ LFG C EN R F++ + +T+F++ T ++WN ++ + + +S Sbjct: 1499 ITCIICINVITMSMEHYNQPKSLDEALKYCNYVFTIVFVFEALFKLVAFGFRRFFKDRWNQLDLAIVLLSIMGITLEEIEINASLPINPTIIRIMRVLRIARVLKLLKMATGMRALLDTVVQALPQVGNLGLLFMLLFFIYAALGVELFGKLVCNEENPCEGLSRHATFENFGMAFLTLFRVSTGDNWNGIMKDTLRECNS 1699 HSP 7 Score: 76.6406 bits (187), Expect = 5.669e-13 Identity = 67/220 (30.45%), Postives = 119/220 (54.09%), Query Frame = 1 Query: 4792 LYWENYSKWRRTINSVVTSKYFDLAIAGVIGLNVITMATEFHMMPQVLKTALKVFNYFFTSTFVXXXXXXXXXXXXXRYISDKWNQLDMMIVILSIAGVVIDEVESNFMPINPTIMRVMRVLRIARVLKLLKMASGIRALLDTVIQALPQVGNXXXXXXXXXXXXXXXXVELFGRLECSDINPCVGLGRHAHFENFGMAFLTLFRIATGDNWNGIMKDTL 5451 L WE ++ + +V SKYF+ I I +N ++M E+H P+ L AL++ N FTS F LE LLKL+A G+ +YI + +N D +IV++S+ +I + + + V+R R+ RVLKL++ +R L +++ + V +L L +IF+ LG+ LFG + + +F++ A +T+F+I T ++WN ++ + + Sbjct: 681 LLWEEFTV---RLKRIVDSKYFNRGIMIAILINTLSMGIEYHEQPEELTNALEISNIVFTSMFALEMLLKLLAFGIFQYIKNPYNIFDGIIVVISVWE-IIGQSDGG--------LSVLRTFRLLRVLKLVRFMPALRRQLVVLVKTMDNVATFCMLLMLFIFIFSILGMHLFGCKFTWTADTGETVKDRKNFDSLLWAIVTVFQILTQEDWNMVLYNGM 888 HSP 8 Score: 73.559 bits (179), Expect = 4.411e-12 Identity = 64/281 (22.78%), Postives = 133/281 (47.33%), Query Frame = 1 Query: 2149 ICQQKIKTLVNDVKFQRGILIAILINTLSMGIEYHQ-QPVQLTQT-LEFSNIVFSILFLIEMILKLIGEGILG----YIKNGFNLFDGIIVVLGVIELCQQGGTSGLSILRTFRLLRILKL-------VRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKFCTIEN-------NKRTCDRK---------NFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTSS----------WAALYFIALMTFGNYVLFNLLVAILVEGFSSER 2874 +CQ+ I + F +L+ I +N +++ +E P L + L SN +F+ +F++EM +K++ G + Y+++ +N+ DGI+V + +I++ ++G + + + L + P L+ + +I ++ + + F IF ILG+ LF KF E N+ C R NFD+L +++++F + +++ W ++Y+G+ ++ W LYFI+ + ++ + N+ V ++VE F R Sbjct: 1168 MCQKVIAHKM----FDHVVLVFIFLNCITIALERPDIDPNSLERIFLSVSNYIFTAIFVLEMAIKVVALGFVSGENTYLQSSWNVLDGILVFVSIIDIVVSLASAGGAKILGVLRVLRLLRTLRPLRVISRAPGLKLVVETLISSLRPIGNIVLICCAFFIIFGILGVQLFKGKFYYCEGLETRNITNRSECTRARYKWVRRKYNFDNLGQALMSLFVLSSKDGWVNIMYDGLDAVATDVQPVKNHNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHKCR 1444 HSP 9 Score: 62.7734 bits (151), Expect = 7.903e-9 Identity = 37/117 (31.62%), Postives = 62/117 (52.99%), Query Frame = 1 Query: 337 FHIFHQNKHPRDWCLKIITWPWFEQLSMTIIAVNCITLSMYQPCGDQNCETSKCQIMQAFDYIIFAFFTCEMVIKIIAMGFL-GDLGYFGDTWNRLDMFIVIVGSIEILPSTGNNIG 684 ++F R C K+I F+ + + I +NCIT+++ +P D N + + + +YI A F EM IK++A+GF+ G+ Y +WN LD +V V I+I+ S + G Sbjct: 1156 LYMFSPQNQFRMMCQKVIAHKMFDHVVLVFIFLNCITIALERPDIDPN--SLERIFLSVSNYIFTAIFVLEMAIKVVALGFVSGENTYLQSSWNVLDGILVFVSIIDIVVSLASAGG 1270 HSP 10 Score: 54.6842 bits (130), Expect = 2.524e-6 Identity = 26/80 (32.50%), Postives = 48/80 (60.00%), Query Frame = 1 Query: 1195 NFDNIGFAWVAIFQVISMESWVDIMYYVQDA----------HSFWDWIYFVALIIIGSFFMINLCLVVIASQFSETKRRE 1404 NFDN+G A +++F + S + WV+IMY DA H+ W +YF++ ++I SFF++N+ + V+ F + ++ + Sbjct: 1368 NFDNLGQALMSLFVLSSKDGWVNIMYDGLDAVATDVQPVKNHNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHKCRQHQ 1447 HSP 11 Score: 53.9138 bits (128), Expect = 4.250e-6 Identity = 24/75 (32.00%), Postives = 44/75 (58.67%), Query Frame = 1 Query: 1195 NFDNIGFAWVAIFQVISMESWVDIMYYVQDAHSFWDWIYFVALIIIGSFFMINLCLVVIASQF---SETKRRETE 1410 NFD++ +A V +FQ+++ E W ++Y + S W +YFVAL+ G++ + NL + ++ F + R +TE Sbjct: 860 NFDSLLWAIVTVFQILTQEDWNMVLYNGMASTSSWAALYFVALMTFGNYVLFNLLVAILVEGFQAEGDATRSDTE 934 HSP 12 Score: 53.1434 bits (126), Expect = 6.805e-6 Identity = 23/78 (29.49%), Postives = 45/78 (57.69%), Query Frame = 1 Query: 2674 NFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTSSWAALYFIALMTFGNYVLFNLLVAILVEGFSSERLDEQKLLHNYR 2907 NFD++ ++ + +FQ++T E W ++Y M S + +YFI L+ G++ + NL + ++ FS + E +L+ R Sbjct: 305 NFDNIGYAWIAIFQVITLEGWVDIMYYVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQRENQLMQEQR 382
BLAST of Voltage-dependent T-type calcium channel subunit alpha vs. Ensembl Xenopus
Match: efhd1 (EF-hand domain family member D1 [Source:Xenbase;Acc:XB-GENE-5738953]) HSP 1 Score: 642.499 bits (1656), Expect = 0.000e+0 Identity = 393/656 (59.91%), Postives = 497/656 (75.76%), Query Frame = 1 Query: 3739 EDP--DEEDMEAMIC--LSKCCPQPKGIFAKRYYH-SLYVFSVDNQFRQKCQHIVDKKSFDYLVLFFITLNCITLAMERPSIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKFYYCDGPHLQAVKTKNDCLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFHKCQENQ--------XXXXXXXXXXXXXXXXXXXXXHLRAPLYWENYSKWRRTINSVVTSKYFDLAIAGVIGLNVITMATEFHMMPQVLKTALKVFNYFFTSTFVXXXXXXXXXXXXXRYISDKWNQLDMMIVILSIAGVVIDEVESNF-MPINPTIMRVMRVLRIARVLKLLKMASGIRALLDTVIQALPQVGNXXXXXXXXXXXXXXXXVELFGRLECSDINPCVGLGRHAHFENFGMAFLTLFRIATGDNWNGIMKDTLREKCISSEDCQRNCCVS-AIIAPIYFVIFXXXXXXXXXXXXXXXXXKHLEESHKMMCDDYELEREVQRDLD 5661 EDP E+D+E C + K K + K + SLY+FS NQFR CQ ++ K FD++VL FI LNCIT+A+ERP I P+S ER+FL+V+NYIFT IF EM IKV++ G + G+ YL+S WN++DG LVF+S++D+ +++ +I G+LRV RLLRTLRPLRVISRAPGLKLVV+TL+SSLRPIGNIVLICC FFIIFGILGVQLFKGKFYYC+G + + +++C + ++ +W +KYNFDNLGQALM+LFVLSSKDGWV IMY G+DAV ++QP +NHN W L+YFISFLL+V+FFVLNMFVGVVVENFHKC+++Q E++ R KR + + R P Y E YS R I+++ TS Y DL I +I +NVITM+ E + P+ L ALK NY FT FV EAL KLVA G R+ D+WNQLD+ IV+LSI G+ ++E+E N +PINPTI+R+MRVLRIARVLKLLKMA+G+RALLDTV+QALPQVGNLGLLF LLF+I+AALGVELFG+L C++ NPC GL RHA FENFGMAFLTLFR++TGDNWNGIMKDTLRE +S+D +NC +I+P+YFV FVL+AQFVLVNVVVAVLMKHLEES+K +D E++ E++ ++D Sbjct: 1202 EDPLEYEDDIEDSYCFRIRKMLEPYKPTWCKTHEDWSLYMFSPQNQFRMMCQKVIAHKMFDHVVLVFIFLNCITIALERPDIDPNSLERIFLSVSNYIFTAIFVLEMAIKVVALGFVSGENTYLQSSWNVLDGILVFVSIIDIVVSLASAGGAKILGVLRVLRLLRTLRPLRVISRAPGLKLVVETLISSLRPIGNIVLICCAFFIIFGILGVQLFKGKFYYCEGLETRNITNRSECTR-ARYKWVRRKYNFDNLGQALMSLFVLSSKDGWVNIMYDGLDAVATDVQPVKNHNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHKCRQHQEAEEARRREEKRLRRLEKKRRSKALYMSEAQRRPYYAE-YSPARLYIHTMCTSHYLDLFITCIICINVITMSMEHYNQPKSLDEALKYCNYVFTIVFVFEALFKLVAFGFRRFFKDRWNQLDLAIVLLSIMGITLEEIEINASLPINPTIIRIMRVLRIARVLKLLKMATGMRALLDTVVQALPQVGNLGLLFMLLFFIYAALGVELFGKLVCNEENPCEGLSRHATFENFGMAFLTLFRVSTGDNWNGIMKDTLRE--CNSDD--KNCLTYLPVISPVYFVTFVLIAQFVLVNVVVAVLMKHLEESNKEAKEDAEMDAEIEMEMD 1851 HSP 2 Score: 407.527 bits (1046), Expect = 3.473e-114 Identity = 233/445 (52.36%), Postives = 311/445 (69.89%), Query Frame = 1 Query: 298 NESLIYHGFYATVFHIFHQNKHPRDWCLKIITWPWFEQLSMTIIAVNCITLSMYQPCGDQNCETSKCQIMQAFDYIIFAFFTCEMVIKIIAMGFLGDLGYFGDTWNRLDMFIVIVGSIEILPSTGNNIGLTAIRTIRVLRPLRAINRIPSMRIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQMWQGVLRNRCYLNLNESFRHPGLNLSSFYQINRTLFLNAVDKDFICSTDKNNGILKCSDIPPSIMLLSNNSLQICKQPARPFTDNLPTKHSCVNWNQYYTDCQPGEKNPYEGAINFDNIGFAWVAIFQVISMESWVDIMYYVQDAHSFWDWIYFVALIIIGSFFMINLCLVVIASQFSETKRRETERMWIERRRFNSSNCSSISKDEPQTCYLEXXXXXXXXXXXXYRRIVKLYNQIQIRHSKTAQGNYQNKLKRQRKHC 1632 E + Y TVF Q PR+WCL+++ P + SM +I +NC+TL M+QPC D NC + +C I++AFD IFAFF EMVIK++A+G G Y GDTWN LD FIV+ G +E G+N+ L+AIRT+RVLRPLRAINR+PSMRILV LLLDTLPMLGNVLLLCFFVFFIFGI+GVQ+W G+LRNRC+++ N + L +YQ++ +A D +ICS++++NG+LKC DIPP + + + + P+++SCVN NQYY C+PGE NP++GAINFDNIG+AW+AIFQVI++E WVDIMYYV DAHSF+++IYF+ LII+GSFFMINLCLVVIA+QFSETK+RE + M +R R+ S++ + S EP +CY E++K I I K+ RR ++LYN Q + K Q N + + + C Sbjct: 57 GEQVPYPALAPTVFFCLSQTTRPRNWCLRLVCNP-YPLHSMLVILLNCVTLGMFQPCEDTNCMSERCNILEAFDGFIFAFFAVEMVIKMVALGIFGQKCYLGDTWNWLDFFIVMAGMLE-YSLDGHNVSLSAIRTVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAGLLRNRCFMDTNFVMSYNFTPLRPYYQVD-----DAEDNPYICSSNRDNGMLKCQDIPPKM------------DCSHVYYSDFPSRNSCVNINQYYNVCKPGEFNPHKGAINFDNIGYAWIAIFQVITLEGWVDIMYYVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQRENQLMQEQRARYLSNDSTIASFSEPGSCYEELLKYICHIFRKVKRRTLRLYNNWQNKRRKKVQPNSNTNSQGRHRKC 482 HSP 3 Score: 344.739 bits (883), Expect = 1.004e-94 Identity = 195/319 (61.13%), Postives = 238/319 (74.61%), Query Frame = 1 Query: 2161 KIKTLVNDVKFQRGILIAILINTLSMGIEYHQQPVQLTQTLEFSNIVFSILFLIEMILKLIGEGILGYIKNGFNLFDGIIVVLGVIELCQQGGTSGLSILRTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKFC-TIENNKRTCDRKNFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTSSWAALYFIALMTFGNYVLFNLLVAILVEGFSSE------RLDEQKLLHNYRQSLKKRRANNKQLRIMQHQSENLVLLTNSIQKDQTGENQKISSQPPVIIHTAATPMPTPRSSP 3096 ++K +V+ F RGI+IAILINTLSMGIEYH+QP +LT LE SNIVF+ +F +EM+LKL+ GI YIKN +N+FDGIIVV+ V E+ Q GLS+LRTFRLLR+LKLVRFMPALR+QL V+++T+DNVATF LL+LFIFIFSILGM LFGCKF T + + DRKNFDSLLW+IVTVFQILTQEDWN VLYNGM TSSWAALYF+ALMTFGNYVLFNLLVAILVEGF +E +E K N+ + L+K K+LR + + +L + N + + S PP+I+ TAATPMPTP+SSP Sbjct: 746 RLKRIVDSKYFNRGIMIAILINTLSMGIEYHEQPEELTNALEISNIVFTSMFALEMLLKLLAFGIFQYIKNPYNIFDGIIVVISVWEIIGQS-DGGLSVLRTFRLLRVLKLVRFMPALRRQLVVLVKTMDNVATFCMLLMLFIFIFSILGMHLFGCKFTWTADTGETVKDRKNFDSLLWAIVTVFQILTQEDWNMVLYNGMASTSSWAALYFVALMTFGNYVLFNLLVAILVEGFQAEGDATRSDTEEDKASGNFDEDLEKL----KELRAAELKMYSLAVTPNG------HLDPRSSMPPPIIMRTAATPMPTPKSSP 1053 HSP 4 Score: 116.316 bits (290), Expect = 4.603e-25 Identity = 73/285 (25.61%), Postives = 141/285 (49.47%), Query Frame = 1 Query: 3841 VFSVDNQFRQKCQHIVDKKSFDYLVLFFITLNCITLAMERPSIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKFYYCDGPHLQAVKTKNDCLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFH 4695 V+ + +F + + IVD K F+ ++ I +N +++ +E P L ++N +FT +F EM++K+L+ G+ Y+K+ +NI DG +V IS+ + ++G S+ +LR FRLLR L+ +R + P L+ + L+ ++ + ++ F IF ILG+ LF KF + E + NFD+L A++ +F + +++ W ++Y G+ + + WA +YF++ + + + N+ V ++VE F Sbjct: 736 VYLLWEEFTVRLKRIVDSKYFNRGIMIAILINTLSMGIEYHEQPEELTNAL--EISNIVFTSMFALEMLLKLLAFGIF----QYIKNPYNIFDGIIVVISVWE-----IIGQSDGGLSVLRTFRLLRVLKLVRFM---PALRRQLVVLVKTMDNVATFCMLLMLFIFIFSILGMHLFGCKFTW----------------TADTGETVKDRKNFDSLLWAIVTVFQILTQEDWNMVLYNGMAST----------SSWAALYFVALMTFGNYVLFNLLVAILVEGFQ 980 HSP 5 Score: 107.071 bits (266), Expect = 3.635e-22 Identity = 99/332 (29.82%), Postives = 157/332 (47.29%), Query Frame = 1 Query: 3916 LFFITLNCITLAMERPSIPPHS-KER--LFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKG---------------------KFYYC-----DGPHL------------QAVKTKNDCLKYSQNEWK--------NQKY---------------NFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFH--KCQENQ 4713 + I LNC+TL M +P + ER + +IF F EM+IK+++ G+ G + YL WN +D F+V +L+ + GH+ + I R +R LRPLR I+R P ++++V LL +L +GN++L+C F IFGI+GVQL+ G + YY D P++ Q + K DC +++ NQ Y NFDN+G A +A+F + + +GWV IMY +DA H+ + IYFI +++ +FF++N+ + V+ F K +ENQ Sbjct: 96 MLVILLNCVTLGMFQPCEDTNCMSERCNILEAFDGFIFAF-FAVEMVIKMVALGIF-GQKCYLGDTWNWLDFFIVMAGMLEYSLD---GHNVSLSAI----RTVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAGLLRNRCFMDTNFVMSYNFTPLRPYYQVDDAEDNPYICSSNRDNGMLKCQDIPPKMDCSHVYYSDFPSRNSCVNINQYYNVCKPGEFNPHKGAINFDNIGYAWIAIFQVITLEGWVDIMYYVMDA----------HSFYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQRENQ 408 HSP 6 Score: 86.2705 bits (212), Expect = 5.791e-16 Identity = 55/201 (27.36%), Postives = 106/201 (52.74%), Query Frame = 1 Query: 2203 ILIAILINTLSMGIEYHQQPVQLTQTLEFSNIVFSILFLIEMILKLIGEGILGYIKNGFNLFDGIIVVLGVIELCQQG---------GTSGLSILRTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKFCTIENNKRTCDR-KNFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTSS 2775 I I IN ++M +E++ QP L + L++ N VF+I+F+ E + KL+ G + K+ +N D IV+L ++ + + + + I+R R+ R+LKL++ +R L +++ + V L +L FI++ LG+ LFG C EN R F++ + +T+F++ T ++WN ++ + + +S Sbjct: 1589 ITCIICINVITMSMEHYNQPKSLDEALKYCNYVFTIVFVFEALFKLVAFGFRRFFKDRWNQLDLAIVLLSIMGITLEEIEINASLPINPTIIRIMRVLRIARVLKLLKMATGMRALLDTVVQALPQVGNLGLLFMLLFFIYAALGVELFGKLVCNEENPCEGLSRHATFENFGMAFLTLFRVSTGDNWNGIMKDTLRECNS 1789 HSP 7 Score: 76.6406 bits (187), Expect = 4.830e-13 Identity = 67/220 (30.45%), Postives = 119/220 (54.09%), Query Frame = 1 Query: 4792 LYWENYSKWRRTINSVVTSKYFDLAIAGVIGLNVITMATEFHMMPQVLKTALKVFNYFFTSTFVXXXXXXXXXXXXXRYISDKWNQLDMMIVILSIAGVVIDEVESNFMPINPTIMRVMRVLRIARVLKLLKMASGIRALLDTVIQALPQVGNXXXXXXXXXXXXXXXXVELFGRLECSDINPCVGLGRHAHFENFGMAFLTLFRIATGDNWNGIMKDTL 5451 L WE ++ + +V SKYF+ I I +N ++M E+H P+ L AL++ N FTS F LE LLKL+A G+ +YI + +N D +IV++S+ +I + + + V+R R+ RVLKL++ +R L +++ + V +L L +IF+ LG+ LFG + + +F++ A +T+F+I T ++WN ++ + + Sbjct: 738 LLWEEFTV---RLKRIVDSKYFNRGIMIAILINTLSMGIEYHEQPEELTNALEISNIVFTSMFALEMLLKLLAFGIFQYIKNPYNIFDGIIVVISVWE-IIGQSDGG--------LSVLRTFRLLRVLKLVRFMPALRRQLVVLVKTMDNVATFCMLLMLFIFIFSILGMHLFGCKFTWTADTGETVKDRKNFDSLLWAIVTVFQILTQEDWNMVLYNGM 945 HSP 8 Score: 74.3294 bits (181), Expect = 2.509e-12 Identity = 64/281 (22.78%), Postives = 133/281 (47.33%), Query Frame = 1 Query: 2149 ICQQKIKTLVNDVKFQRGILIAILINTLSMGIEYHQ-QPVQLTQT-LEFSNIVFSILFLIEMILKLIGEGILG----YIKNGFNLFDGIIVVLGVIELCQQGGTSGLSILRTFRLLRILKL-------VRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKFCTIEN-------NKRTCDRK---------NFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTSS----------WAALYFIALMTFGNYVLFNLLVAILVEGFSSER 2874 +CQ+ I + F +L+ I +N +++ +E P L + L SN +F+ +F++EM +K++ G + Y+++ +N+ DGI+V + +I++ ++G + + + L + P L+ + +I ++ + + F IF ILG+ LF KF E N+ C R NFD+L +++++F + +++ W ++Y+G+ ++ W LYFI+ + ++ + N+ V ++VE F R Sbjct: 1251 MCQKVIAHKM----FDHVVLVFIFLNCITIALERPDIDPNSLERIFLSVSNYIFTAIFVLEMAIKVVALGFVSGENTYLQSSWNVLDGILVFVSIIDIVVSLASAGGAKILGVLRVLRLLRTLRPLRVISRAPGLKLVVETLISSLRPIGNIVLICCAFFIIFGILGVQLFKGKFYYCEGLETRNITNRSECTRARYKWVRRKYNFDNLGQALMSLFVLSSKDGWVNIMYDGLDAVATDVQPVKNHNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHKCR 1527 HSP 9 Score: 63.5438 bits (153), Expect = 5.876e-9 Identity = 37/117 (31.62%), Postives = 62/117 (52.99%), Query Frame = 1 Query: 337 FHIFHQNKHPRDWCLKIITWPWFEQLSMTIIAVNCITLSMYQPCGDQNCETSKCQIMQAFDYIIFAFFTCEMVIKIIAMGFL-GDLGYFGDTWNRLDMFIVIVGSIEILPSTGNNIG 684 ++F R C K+I F+ + + I +NCIT+++ +P D N + + + +YI A F EM IK++A+GF+ G+ Y +WN LD +V V I+I+ S + G Sbjct: 1239 LYMFSPQNQFRMMCQKVIAHKMFDHVVLVFIFLNCITIALERPDIDPN--SLERIFLSVSNYIFTAIFVLEMAIKVVALGFVSGENTYLQSSWNVLDGILVFVSIIDIVVSLASAGG 1353 HSP 10 Score: 54.6842 bits (130), Expect = 2.274e-6 Identity = 26/80 (32.50%), Postives = 48/80 (60.00%), Query Frame = 1 Query: 1195 NFDNIGFAWVAIFQVISMESWVDIMYYVQDA----------HSFWDWIYFVALIIIGSFFMINLCLVVIASQFSETKRRE 1404 NFDN+G A +++F + S + WV+IMY DA H+ W +YF++ ++I SFF++N+ + V+ F + ++ + Sbjct: 1451 NFDNLGQALMSLFVLSSKDGWVNIMYDGLDAVATDVQPVKNHNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHKCRQHQ 1530 HSP 11 Score: 53.9138 bits (128), Expect = 4.062e-6 Identity = 24/75 (32.00%), Postives = 44/75 (58.67%), Query Frame = 1 Query: 1195 NFDNIGFAWVAIFQVISMESWVDIMYYVQDAHSFWDWIYFVALIIIGSFFMINLCLVVIASQF---SETKRRETE 1410 NFD++ +A V +FQ+++ E W ++Y + S W +YFVAL+ G++ + NL + ++ F + R +TE Sbjct: 917 NFDSLLWAIVTVFQILTQEDWNMVLYNGMASTSSWAALYFVALMTFGNYVLFNLLVAILVEGFQAEGDATRSDTE 991 HSP 12 Score: 53.5286 bits (127), Expect = 6.131e-6 Identity = 23/78 (29.49%), Postives = 45/78 (57.69%), Query Frame = 1 Query: 2674 NFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTSSWAALYFIALMTFGNYVLFNLLVAILVEGFSSERLDEQKLLHNYR 2907 NFD++ ++ + +FQ++T E W ++Y M S + +YFI L+ G++ + NL + ++ FS + E +L+ R Sbjct: 337 NFDNIGYAWIAIFQVITLEGWVDIMYYVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQRENQLMQEQR 414
BLAST of Voltage-dependent T-type calcium channel subunit alpha vs. Ensembl Xenopus
Match: efhd1 (EF-hand domain family member D1 [Source:Xenbase;Acc:XB-GENE-5738953]) HSP 1 Score: 641.728 bits (1654), Expect = 0.000e+0 Identity = 396/678 (58.41%), Postives = 503/678 (74.19%), Query Frame = 1 Query: 3739 EDP--DEEDMEAMIC--LSKCCPQPKGIFAKRYYH-SLYVFSVDNQFRQKCQHIVDKKSFDYLVLFFITLNCITLAMERPSIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKFYYCDGPHLQAVKTKNDCLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFHKCQENQ--------XXXXXXXXXXXXXXXXXXXXXHLRAPLYWENYSKWRRTINSVVTSKYFDLAIAGVIGLNVITMATEFHMMPQVLKTALKVFNYFFTSTFVXXXXXXXXXXXXXRYISDKWNQLDMMIVILSIAGVVIDEVESNF-MPINPTIMRVMRVLRIARVLKLLKMASGIRALLDTVIQALPQVGNXXXXXXXXXXXXXXXXVELFGRLECSDINPCVGLGRHAHFENFGMAFLTLFRIATGDNWNGIMKDTLREKCISSEDCQRNCCVS-AIIAPIYFVIFXXXXXXXXXXXXXXXXXKHLEESHKMMCDDYELEREVQRDLDEEAKELAREKQLKDEENNENTL 5727 EDP E+D+E C + K K + K + SLY+FS NQFR CQ ++ K FD++VL FI LNCIT+A+ERP I P+S ER+FL+V+NYIFT IF EM IKV++ G + G+ YL+S WN++DG LVF+S++D+ +++ +I G+LRV RLLRTLRPLRVISRAPGLKLVV+TL+SSLRPIGNIVLICC FFIIFGILGVQLFKGKFYYC+G + + +++C + ++ +W +KYNFDNLGQALM+LFVLSSKDGWV IMY G+DAV ++QP +NHN W L+YFISFLL+V+FFVLNMFVGVVVENFHKC+++Q E++ R KR + + R P Y E YS R I+++ TS Y DL I +I +NVITM+ E + P+ L ALK NY FT FV EAL KLVA G R+ D+WNQLD+ IV+LSI G+ ++E+E N +PINPTI+R+MRVLRIARVLKLLKMA+G+RALLDTV+QALPQVGNLGLLF LLF+I+AALGVELFG+L C++ NPC GL RHA FENFGMAFLTLFR++TGDNWNGIMKDTLRE C S + +NC +I+P+YFV FVL+AQFVLVNVVVAVLMKHLEES+K +D E++ E++ ++ + + Q +D + N L Sbjct: 1212 EDPLEYEDDIEDSYCFRIRKMLEPYKPTWCKTHEDWSLYMFSPQNQFRMMCQKVIAHKMFDHVVLVFIFLNCITIALERPDIDPNSLERIFLSVSNYIFTAIFVLEMAIKVVALGFVSGENTYLQSSWNVLDGILVFVSIIDIVVSLASAGGAKILGVLRVLRLLRTLRPLRVISRAPGLKLVVETLISSLRPIGNIVLICCAFFIIFGILGVQLFKGKFYYCEGLETRNITNRSECTR-ARYKWVRRKYNFDNLGQALMSLFVLSSKDGWVNIMYDGLDAVATDVQPVKNHNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHKCRQHQEAEEARRREEKRLRRLEKKRRSKALYMSEAQRRPYYAE-YSPARLYIHTMCTSHYLDLFITCIICINVITMSMEHYNQPKSLDEALKYCNYVFTIVFVFEALFKLVAFGFRRFFKDRWNQLDLAIVLLSIMGITLEEIEINASLPINPTIIRIMRVLRIARVLKLLKMATGMRALLDTVVQALPQVGNLGLLFMLLFFIYAALGVELFGKLVCNEENPCEGLSRHATFENFGMAFLTLFRVSTGDNWNGIMKDTLRE-CNSDD---KNCLTYLPVISPVYFVTFVLIAQFVLVNVVVAVLMKHLEESNKEAKEDAEMDAEIEMEMSRDG-----DFQRRDGSGSRNLL 1878 HSP 2 Score: 407.527 bits (1046), Expect = 3.009e-114 Identity = 233/445 (52.36%), Postives = 311/445 (69.89%), Query Frame = 1 Query: 298 NESLIYHGFYATVFHIFHQNKHPRDWCLKIITWPWFEQLSMTIIAVNCITLSMYQPCGDQNCETSKCQIMQAFDYIIFAFFTCEMVIKIIAMGFLGDLGYFGDTWNRLDMFIVIVGSIEILPSTGNNIGLTAIRTIRVLRPLRAINRIPSMRIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQMWQGVLRNRCYLNLNESFRHPGLNLSSFYQINRTLFLNAVDKDFICSTDKNNGILKCSDIPPSIMLLSNNSLQICKQPARPFTDNLPTKHSCVNWNQYYTDCQPGEKNPYEGAINFDNIGFAWVAIFQVISMESWVDIMYYVQDAHSFWDWIYFVALIIIGSFFMINLCLVVIASQFSETKRRETERMWIERRRFNSSNCSSISKDEPQTCYLEXXXXXXXXXXXXYRRIVKLYNQIQIRHSKTAQGNYQNKLKRQRKHC 1632 E + Y TVF Q PR+WCL+++ P + SM +I +NC+TL M+QPC D NC + +C I++AFD IFAFF EMVIK++A+G G Y GDTWN LD FIV+ G +E G+N+ L+AIRT+RVLRPLRAINR+PSMRILV LLLDTLPMLGNVLLLCFFVFFIFGI+GVQ+W G+LRNRC+++ N + L +YQ++ +A D +ICS++++NG+LKC DIPP + + + + P+++SCVN NQYY C+PGE NP++GAINFDNIG+AW+AIFQVI++E WVDIMYYV DAHSF+++IYF+ LII+GSFFMINLCLVVIA+QFSETK+RE + M +R R+ S++ + S EP +CY E++K I I K+ RR ++LYN Q + K Q N + + + C Sbjct: 67 GEQVPYPALAPTVFFCLSQTTRPRNWCLRLVCNP-YPLHSMLVILLNCVTLGMFQPCEDTNCMSERCNILEAFDGFIFAFFAVEMVIKMVALGIFGQKCYLGDTWNWLDFFIVMAGMLE-YSLDGHNVSLSAIRTVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAGLLRNRCFMDTNFVMSYNFTPLRPYYQVD-----DAEDNPYICSSNRDNGMLKCQDIPPKM------------DCSHVYYSDFPSRNSCVNINQYYNVCKPGEFNPHKGAINFDNIGYAWIAIFQVITLEGWVDIMYYVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQRENQLMQEQRARYLSNDSTIASFSEPGSCYEELLKYICHIFRKVKRRTLRLYNNWQNKRRKKVQPNSNTNSQGRHRKC 492 HSP 3 Score: 345.125 bits (884), Expect = 8.368e-95 Identity = 195/319 (61.13%), Postives = 238/319 (74.61%), Query Frame = 1 Query: 2161 KIKTLVNDVKFQRGILIAILINTLSMGIEYHQQPVQLTQTLEFSNIVFSILFLIEMILKLIGEGILGYIKNGFNLFDGIIVVLGVIELCQQGGTSGLSILRTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKFC-TIENNKRTCDRKNFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTSSWAALYFIALMTFGNYVLFNLLVAILVEGFSSE------RLDEQKLLHNYRQSLKKRRANNKQLRIMQHQSENLVLLTNSIQKDQTGENQKISSQPPVIIHTAATPMPTPRSSP 3096 ++K +V+ F RGI+IAILINTLSMGIEYH+QP +LT LE SNIVF+ +F +EM+LKL+ GI YIKN +N+FDGIIVV+ V E+ Q GLS+LRTFRLLR+LKLVRFMPALR+QL V+++T+DNVATF LL+LFIFIFSILGM LFGCKF T + + DRKNFDSLLW+IVTVFQILTQEDWN VLYNGM TSSWAALYF+ALMTFGNYVLFNLLVAILVEGF +E +E K N+ + L+K K+LR + + +L + N + + S PP+I+ TAATPMPTP+SSP Sbjct: 756 RLKRIVDSKYFNRGIMIAILINTLSMGIEYHEQPEELTNALEISNIVFTSMFALEMLLKLLAFGIFQYIKNPYNIFDGIIVVISVWEIIGQS-DGGLSVLRTFRLLRVLKLVRFMPALRRQLVVLVKTMDNVATFCMLLMLFIFIFSILGMHLFGCKFTWTADTGETVKDRKNFDSLLWAIVTVFQILTQEDWNMVLYNGMASTSSWAALYFVALMTFGNYVLFNLLVAILVEGFQAEGDATRSDTEEDKASGNFDEDLEKL----KELRAAELKMYSLAVTPNG------HLDPRSSMPPPIIMRTAATPMPTPKSSP 1063 HSP 4 Score: 116.316 bits (290), Expect = 4.679e-25 Identity = 73/285 (25.61%), Postives = 141/285 (49.47%), Query Frame = 1 Query: 3841 VFSVDNQFRQKCQHIVDKKSFDYLVLFFITLNCITLAMERPSIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKFYYCDGPHLQAVKTKNDCLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFH 4695 V+ + +F + + IVD K F+ ++ I +N +++ +E P L ++N +FT +F EM++K+L+ G+ Y+K+ +NI DG +V IS+ + ++G S+ +LR FRLLR L+ +R + P L+ + L+ ++ + ++ F IF ILG+ LF KF + E + NFD+L A++ +F + +++ W ++Y G+ + + WA +YF++ + + + N+ V ++VE F Sbjct: 746 VYLLWEEFTVRLKRIVDSKYFNRGIMIAILINTLSMGIEYHEQPEELTNAL--EISNIVFTSMFALEMLLKLLAFGIF----QYIKNPYNIFDGIIVVISVWE-----IIGQSDGGLSVLRTFRLLRVLKLVRFM---PALRRQLVVLVKTMDNVATFCMLLMLFIFIFSILGMHLFGCKFTW----------------TADTGETVKDRKNFDSLLWAIVTVFQILTQEDWNMVLYNGMAST----------SSWAALYFVALMTFGNYVLFNLLVAILVEGFQ 990 HSP 5 Score: 106.686 bits (265), Expect = 3.727e-22 Identity = 99/332 (29.82%), Postives = 157/332 (47.29%), Query Frame = 1 Query: 3916 LFFITLNCITLAMERPSIPPHS-KER--LFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKG---------------------KFYYC-----DGPHL------------QAVKTKNDCLKYSQNEWK--------NQKY---------------NFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFH--KCQENQ 4713 + I LNC+TL M +P + ER + +IF F EM+IK+++ G+ G + YL WN +D F+V +L+ + GH+ + I R +R LRPLR I+R P ++++V LL +L +GN++L+C F IFGI+GVQL+ G + YY D P++ Q + K DC +++ NQ Y NFDN+G A +A+F + + +GWV IMY +DA H+ + IYFI +++ +FF++N+ + V+ F K +ENQ Sbjct: 106 MLVILLNCVTLGMFQPCEDTNCMSERCNILEAFDGFIFAF-FAVEMVIKMVALGIF-GQKCYLGDTWNWLDFFIVMAGMLEYSLD---GHNVSLSAI----RTVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAGLLRNRCFMDTNFVMSYNFTPLRPYYQVDDAEDNPYICSSNRDNGMLKCQDIPPKMDCSHVYYSDFPSRNSCVNINQYYNVCKPGEFNPHKGAINFDNIGYAWIAIFQVITLEGWVDIMYYVMDA----------HSFYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQRENQ 418 HSP 6 Score: 86.2705 bits (212), Expect = 5.888e-16 Identity = 55/201 (27.36%), Postives = 106/201 (52.74%), Query Frame = 1 Query: 2203 ILIAILINTLSMGIEYHQQPVQLTQTLEFSNIVFSILFLIEMILKLIGEGILGYIKNGFNLFDGIIVVLGVIELCQQG---------GTSGLSILRTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKFCTIENNKRTCDR-KNFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTSS 2775 I I IN ++M +E++ QP L + L++ N VF+I+F+ E + KL+ G + K+ +N D IV+L ++ + + + + I+R R+ R+LKL++ +R L +++ + V L +L FI++ LG+ LFG C EN R F++ + +T+F++ T ++WN ++ + + +S Sbjct: 1599 ITCIICINVITMSMEHYNQPKSLDEALKYCNYVFTIVFVFEALFKLVAFGFRRFFKDRWNQLDLAIVLLSIMGITLEEIEINASLPINPTIIRIMRVLRIARVLKLLKMATGMRALLDTVVQALPQVGNLGLLFMLLFFIYAALGVELFGKLVCNEENPCEGLSRHATFENFGMAFLTLFRVSTGDNWNGIMKDTLRECNS 1799 HSP 7 Score: 76.6406 bits (187), Expect = 4.994e-13 Identity = 67/216 (31.02%), Postives = 117/216 (54.17%), Query Frame = 1 Query: 4792 LYWENYSKWRRTINSVVTSKYFDLAIAGVIGLNVITMATEFHMMPQVLKTALKVFNYFFTSTFVXXXXXXXXXXXXXRYISDKWNQLDMMIVILSIAGVVIDEVESNFMPINPTIMRVMRVLRIARVLKLLKMASGIRALLDTVIQALPQVGNXXXXXXXXXXXXXXXXVELFGRLECSDINPCVGLGRHAHFENFGMAFLTLFRIATGDNWNGIM 5439 L WE ++ + +V SKYF+ I I +N ++M E+H P+ L AL++ N FTS F LE LLKL+A G+ +YI + +N D +IV++S+ +I + + + V+R R+ RVLKL++ +R L +++ + V +L L +IF+ LG+ LFG + + +F++ A +T+F+I T ++WN ++ Sbjct: 748 LLWEEFTV---RLKRIVDSKYFNRGIMIAILINTLSMGIEYHEQPEELTNALEISNIVFTSMFALEMLLKLLAFGIFQYIKNPYNIFDGIIVVISVWE-IIGQSDGG--------LSVLRTFRLLRVLKLVRFMPALRRQLVVLVKTMDNVATFCMLLMLFIFIFSILGMHLFGCKFTWTADTGETVKDRKNFDSLLWAIVTVFQILTQEDWNMVL 951 HSP 8 Score: 74.3294 bits (181), Expect = 2.706e-12 Identity = 64/281 (22.78%), Postives = 133/281 (47.33%), Query Frame = 1 Query: 2149 ICQQKIKTLVNDVKFQRGILIAILINTLSMGIEYHQ-QPVQLTQT-LEFSNIVFSILFLIEMILKLIGEGILG----YIKNGFNLFDGIIVVLGVIELCQQGGTSGLSILRTFRLLRILKL-------VRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKFCTIEN-------NKRTCDRK---------NFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTSS----------WAALYFIALMTFGNYVLFNLLVAILVEGFSSER 2874 +CQ+ I + F +L+ I +N +++ +E P L + L SN +F+ +F++EM +K++ G + Y+++ +N+ DGI+V + +I++ ++G + + + L + P L+ + +I ++ + + F IF ILG+ LF KF E N+ C R NFD+L +++++F + +++ W ++Y+G+ ++ W LYFI+ + ++ + N+ V ++VE F R Sbjct: 1261 MCQKVIAHKM----FDHVVLVFIFLNCITIALERPDIDPNSLERIFLSVSNYIFTAIFVLEMAIKVVALGFVSGENTYLQSSWNVLDGILVFVSIIDIVVSLASAGGAKILGVLRVLRLLRTLRPLRVISRAPGLKLVVETLISSLRPIGNIVLICCAFFIIFGILGVQLFKGKFYYCEGLETRNITNRSECTRARYKWVRRKYNFDNLGQALMSLFVLSSKDGWVNIMYDGLDAVATDVQPVKNHNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHKCR 1537 HSP 9 Score: 63.5438 bits (153), Expect = 5.875e-9 Identity = 37/117 (31.62%), Postives = 62/117 (52.99%), Query Frame = 1 Query: 337 FHIFHQNKHPRDWCLKIITWPWFEQLSMTIIAVNCITLSMYQPCGDQNCETSKCQIMQAFDYIIFAFFTCEMVIKIIAMGFL-GDLGYFGDTWNRLDMFIVIVGSIEILPSTGNNIG 684 ++F R C K+I F+ + + I +NCIT+++ +P D N + + + +YI A F EM IK++A+GF+ G+ Y +WN LD +V V I+I+ S + G Sbjct: 1249 LYMFSPQNQFRMMCQKVIAHKMFDHVVLVFIFLNCITIALERPDIDPN--SLERIFLSVSNYIFTAIFVLEMAIKVVALGFVSGENTYLQSSWNVLDGILVFVSIIDIVVSLASAGG 1363 HSP 10 Score: 55.0694 bits (131), Expect = 2.181e-6 Identity = 26/80 (32.50%), Postives = 48/80 (60.00%), Query Frame = 1 Query: 1195 NFDNIGFAWVAIFQVISMESWVDIMYYVQDA----------HSFWDWIYFVALIIIGSFFMINLCLVVIASQFSETKRRE 1404 NFDN+G A +++F + S + WV+IMY DA H+ W +YF++ ++I SFF++N+ + V+ F + ++ + Sbjct: 1461 NFDNLGQALMSLFVLSSKDGWVNIMYDGLDAVATDVQPVKNHNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHKCRQHQ 1540 HSP 11 Score: 53.9138 bits (128), Expect = 3.927e-6 Identity = 24/75 (32.00%), Postives = 44/75 (58.67%), Query Frame = 1 Query: 1195 NFDNIGFAWVAIFQVISMESWVDIMYYVQDAHSFWDWIYFVALIIIGSFFMINLCLVVIASQF---SETKRRETE 1410 NFD++ +A V +FQ+++ E W ++Y + S W +YFVAL+ G++ + NL + ++ F + R +TE Sbjct: 927 NFDSLLWAIVTVFQILTQEDWNMVLYNGMASTSSWAALYFVALMTFGNYVLFNLLVAILVEGFQAEGDATRSDTE 1001 HSP 12 Score: 53.5286 bits (127), Expect = 5.731e-6 Identity = 23/78 (29.49%), Postives = 45/78 (57.69%), Query Frame = 1 Query: 2674 NFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTSSWAALYFIALMTFGNYVLFNLLVAILVEGFSSERLDEQKLLHNYR 2907 NFD++ ++ + +FQ++T E W ++Y M S + +YFI L+ G++ + NL + ++ FS + E +L+ R Sbjct: 347 NFDNIGYAWIAIFQVITLEGWVDIMYYVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQRENQLMQEQR 424
BLAST of Voltage-dependent T-type calcium channel subunit alpha vs. Ensembl Xenopus
Match: efhd1 (EF-hand domain family member D1 [Source:Xenbase;Acc:XB-GENE-5738953]) HSP 1 Score: 637.491 bits (1643), Expect = 0.000e+0 Identity = 382/619 (61.71%), Postives = 481/619 (77.71%), Query Frame = 1 Query: 3832 SLYVFSVDNQFRQKCQHIVDKKSFDYLVLFFITLNCITLAMERPSIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKFYYCDGPHLQAVKTKNDCLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFHKCQENQ--------XXXXXXXXXXXXXXXXXXXXXHLRAPLYWENYSKWRRTINSVVTSKYFDLAIAGVIGLNVITMATEFHMMPQVLKTALKVFNYFFTSTFVXXXXXXXXXXXXXRYISDKWNQLDMMIVILSIAGVVIDEVESNF-MPINPTIMRVMRVLRIARVLKLLKMASGIRALLDTVIQALPQVGNXXXXXXXXXXXXXXXXVELFGRLECSDINPCVGLGRHAHFENFGMAFLTLFRIATGDNWNGIMKDTLREKCISSEDCQRNCCVS-AIIAPIYFVIFXXXXXXXXXXXXXXXXXKHLEESHKMMCDDYELEREVQRDL 5658 SLY+FS NQFR CQ ++ K FD++VL FI LNCIT+A+ERP I P+S ER+FL+V+NYIFT IF EM IKV++ G + G+ YL+S WN++DG LVF+S++D+ +++ +I G+LRV RLLRTLRPLRVISRAPGLKLVV+TL+SSLRPIGNIVLICC FFIIFGILGVQLFKGKFYYC+G + + +++C + ++ +W +KYNFDNLGQALM+LFVLSSKDGWV IMY G+DAV ++QP +NHN W L+YFISFLL+V+FFVLNMFVGVVVENFHKC+++Q E++ R KR + + R P Y E YS R I+++ TS Y DL I +I +NVITM+ E + P+ L ALK NY FT FV EAL KLVA G R+ D+WNQLD+ IV+LSI G+ ++E+E N +PINPTI+R+MRVLRIARVLKLLKMA+G+RALLDTV+QALPQVGNLGLLF LLF+I+AALGVELFG+L C++ NPC GL RHA FENFGMAFLTLFR++TGDNWNGIMKDTLRE +S+D +NC +I+P+YFV FVL+AQFVLVNVVVAVLMKHLEES+K +D E++ E++ ++ Sbjct: 1181 SLYMFSPQNQFRMMCQKVIAHKMFDHVVLVFIFLNCITIALERPDIDPNSLERIFLSVSNYIFTAIFVLEMAIKVVALGFVSGENTYLQSSWNVLDGILVFVSIIDIVVSLASAGGAKILGVLRVLRLLRTLRPLRVISRAPGLKLVVETLISSLRPIGNIVLICCAFFIIFGILGVQLFKGKFYYCEGLETRNITNRSECTR-ARYKWVRRKYNFDNLGQALMSLFVLSSKDGWVNIMYDGLDAVATDVQPVKNHNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHKCRQHQEAEEARRREEKRLRRLEKKRRSKALYMSEAQRRPYYAE-YSPARLYIHTMCTSHYLDLFITCIICINVITMSMEHYNQPKSLDEALKYCNYVFTIVFVFEALFKLVAFGFRRFFKDRWNQLDLAIVLLSIMGITLEEIEINASLPINPTIIRIMRVLRIARVLKLLKMATGMRALLDTVVQALPQVGNLGLLFMLLFFIYAALGVELFGKLVCNEENPCEGLSRHATFENFGMAFLTLFRVSTGDNWNGIMKDTLRE--CNSDD--KNCLTYLPVISPVYFVTFVLIAQFVLVNVVVAVLMKHLEESNKEAKEDAEMDAEIEMEM 1793 HSP 2 Score: 397.512 bits (1020), Expect = 4.025e-111 Identity = 232/445 (52.13%), Postives = 307/445 (68.99%), Query Frame = 1 Query: 298 NESLIYHGFYATVFHIFHQNKHPRDWCLKIITWPWFEQLSMTIIAVNCITLSMYQPCGDQNCETSKCQIMQAFDYIIFAFFTCEMVIKIIAMGFLGDLGYFGDTWNRLDMFIVIVGSIEILPSTGNNIGLTAIRTIRVLRPLRAINRIPSMRIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQMWQGVLRNRCYLNLNESFRHPGLNLSSFYQINRTLFLNAVDKDFICSTDKNNGILKCSDIPPSIMLLSNNSLQICKQPARPFTDNLPTKHSCVNWNQYYTDCQPGEKNPYEGAINFDNIGFAWVAIFQVISMESWVDIMYYVQDAHSFWDWIYFVALIIIGSFFMINLCLVVIASQFSETKRRETERMWIERRRFNSSNCSSISKDEPQTCYLEXXXXXXXXXXXXYRRIVKLYNQIQIRHSKTAQGNYQNKLKRQRKHC 1632 E + Y TVF Q PR+WCL+++ P + SM +I +NC+TL M+QPC D NC + +C I++AFD IFAFF EMVIK++A+G G Y GDTWN LD FIV+ G +E G+N+ L+AIRT+RVLRPLRAINR+PSMRILV LLLDTLPMLGNVLLLCFFVFFIFGI+GVQ+W G+LRNRC+++ N F I+ +A D +ICS++++NG+LKC DIPP + + + + P+++SCVN NQYY C+PGE NP++GAINFDNIG+AW+AIFQVI++E WVDIMYYV DAHSF+++IYF+ LII+GSFFMINLCLVVIA+QFSETK+RE + M +R R+ S++ + S EP +CY E++K I I K+ RR ++LYN Q + K Q N + + + C Sbjct: 67 GEQVPYPALAPTVFFCLSQTTRPRNWCLRLVCNP-YPLHSMLVILLNCVTLGMFQPCEDTNCMSERCNILEAFDGFIFAFFAVEMVIKMVALGIFGQKCYLGDTWNWLDFFIVMAGMLE-YSLDGHNVSLSAIRTVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAGLLRNRCFMDTN------------FLPISVD---DAEDNPYICSSNRDNGMLKCQDIPPKM------------DCSHVYYSDFPSRNSCVNINQYYNVCKPGEFNPHKGAINFDNIGYAWIAIFQVITLEGWVDIMYYVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQRENQLMQEQRARYLSNDSTIASFSEPGSCYEELLKYICHIFRKVKRRTLRLYNNWQNKRRKKVQPNSNTNSQGRHRKC 482 HSP 3 Score: 327.405 bits (838), Expect = 2.246e-89 Identity = 187/314 (59.55%), Postives = 222/314 (70.70%), Query Frame = 1 Query: 2161 KIKTLVNDVKFQRGILIAILINTLSMGIEYHQQPVQLTQTLEFSNIVFSILFLIEMILKLIGEGILGYIKNGFNLFDGIIVVLGVIELCQQGGTSGLSILRTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKFC-TIENNKRTCDRKNFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTSSWAALYFIALMTFGNYVLFNLLVAILVEGFSSERLDEQKLLHNYRQSLKKRRANNKQLRIMQHQSENLVLLTNSIQKDQTGE-NQKISSQPPVIIHTAATPMPTPRSSP 3096 ++K +V+ F RGI+IAILINTLSMGIEYH+QP +LT LE SNIVF+ +F +EM+LKL+ GI YIKN +N+FDGIIVV+ V E+ Q GLS+LRTFRLLR+LKLVRFMPALR+QL V+++T+DNVATF LL+LFIFIFSILGM LFGCKF T + + DRKNFDSLLW+IVTVFQILTQEDWN VLYNGM TSSWAALYF+ALMTFGNYVLFNLLVAILVEGF +E S+ G + + S PP+I+ TAATPMPTP+SSP Sbjct: 706 RLKRIVDSKYFNRGIMIAILINTLSMGIEYHEQPEELTNALEISNIVFTSMFALEMLLKLLAFGIFQYIKNPYNIFDGIIVVISVWEIIGQS-DGGLSVLRTFRLLRVLKLVRFMPALRRQLVVLVKTMDNVATFCMLLMLFIFIFSILGMHLFGCKFTWTADTGETVKDRKNFDSLLWAIVTVFQILTQEDWNMVLYNGMASTSSWAALYFVALMTFGNYVLFNLLVAILVEGFQAEMY--------------------------------------SLAVTPNGHLDPRSSMPPPIIMRTAATPMPTPKSSP 980 HSP 4 Score: 115.931 bits (289), Expect = 6.594e-25 Identity = 73/285 (25.61%), Postives = 141/285 (49.47%), Query Frame = 1 Query: 3841 VFSVDNQFRQKCQHIVDKKSFDYLVLFFITLNCITLAMERPSIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKFYYCDGPHLQAVKTKNDCLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFH 4695 V+ + +F + + IVD K F+ ++ I +N +++ +E P L ++N +FT +F EM++K+L+ G+ Y+K+ +NI DG +V IS+ + ++G S+ +LR FRLLR L+ +R + P L+ + L+ ++ + ++ F IF ILG+ LF KF + E + NFD+L A++ +F + +++ W ++Y G+ + + WA +YF++ + + + N+ V ++VE F Sbjct: 696 VYLLWEEFTVRLKRIVDSKYFNRGIMIAILINTLSMGIEYHEQPEELTNAL--EISNIVFTSMFALEMLLKLLAFGIF----QYIKNPYNIFDGIIVVISVWE-----IIGQSDGGLSVLRTFRLLRVLKLVRFM---PALRRQLVVLVKTMDNVATFCMLLMLFIFIFSILGMHLFGCKFTW----------------TADTGETVKDRKNFDSLLWAIVTVFQILTQEDWNMVLYNGMAST----------SSWAALYFVALMTFGNYVLFNLLVAILVEGFQ 940 HSP 5 Score: 108.227 bits (269), Expect = 1.619e-22 Identity = 98/322 (30.43%), Postives = 155/322 (48.14%), Query Frame = 1 Query: 3916 LFFITLNCITLAMERPSIPPHS-KER--LFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKFY-YC---------------DGPHL------------QAVKTKNDCLKYSQNEWK--------NQKY---------------NFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFH--KCQENQ 4713 + I LNC+TL M +P + ER + +IF F EM+IK+++ G+ G + YL WN +D F+V +L+ + GH+ + I R +R LRPLR I+R P ++++V LL +L +GN++L+C F IFGI+GVQL+ G C D P++ Q + K DC +++ NQ Y NFDN+G A +A+F + + +GWV IMY +DA H+ + IYFI +++ +FF++N+ + V+ F K +ENQ Sbjct: 106 MLVILLNCVTLGMFQPCEDTNCMSERCNILEAFDGFIFAF-FAVEMVIKMVALGIF-GQKCYLGDTWNWLDFFIVMAGMLEYSLD---GHNVSLSAI----RTVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAGLLRNRCFMDTNFLPISVDDAEDNPYICSSNRDNGMLKCQDIPPKMDCSHVYYSDFPSRNSCVNINQYYNVCKPGEFNPHKGAINFDNIGYAWIAIFQVITLEGWVDIMYYVMDA----------HSFYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQRENQ 408 HSP 6 Score: 86.2705 bits (212), Expect = 6.977e-16 Identity = 55/201 (27.36%), Postives = 106/201 (52.74%), Query Frame = 1 Query: 2203 ILIAILINTLSMGIEYHQQPVQLTQTLEFSNIVFSILFLIEMILKLIGEGILGYIKNGFNLFDGIIVVLGVIELCQQG---------GTSGLSILRTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKFCTIENNKRTCDR-KNFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTSS 2775 I I IN ++M +E++ QP L + L++ N VF+I+F+ E + KL+ G + K+ +N D IV+L ++ + + + + I+R R+ R+LKL++ +R L +++ + V L +L FI++ LG+ LFG C EN R F++ + +T+F++ T ++WN ++ + + +S Sbjct: 1532 ITCIICINVITMSMEHYNQPKSLDEALKYCNYVFTIVFVFEALFKLVAFGFRRFFKDRWNQLDLAIVLLSIMGITLEEIEINASLPINPTIIRIMRVLRIARVLKLLKMATGMRALLDTVVQALPQVGNLGLLFMLLFFIYAALGVELFGKLVCNEENPCEGLSRHATFENFGMAFLTLFRVSTGDNWNGIMKDTLRECNS 1732 HSP 7 Score: 77.0258 bits (188), Expect = 4.564e-13 Identity = 67/220 (30.45%), Postives = 119/220 (54.09%), Query Frame = 1 Query: 4792 LYWENYSKWRRTINSVVTSKYFDLAIAGVIGLNVITMATEFHMMPQVLKTALKVFNYFFTSTFVXXXXXXXXXXXXXRYISDKWNQLDMMIVILSIAGVVIDEVESNFMPINPTIMRVMRVLRIARVLKLLKMASGIRALLDTVIQALPQVGNXXXXXXXXXXXXXXXXVELFGRLECSDINPCVGLGRHAHFENFGMAFLTLFRIATGDNWNGIMKDTL 5451 L WE ++ + +V SKYF+ I I +N ++M E+H P+ L AL++ N FTS F LE LLKL+A G+ +YI + +N D +IV++S+ +I + + + V+R R+ RVLKL++ +R L +++ + V +L L +IF+ LG+ LFG + + +F++ A +T+F+I T ++WN ++ + + Sbjct: 698 LLWEEFTV---RLKRIVDSKYFNRGIMIAILINTLSMGIEYHEQPEELTNALEISNIVFTSMFALEMLLKLLAFGIFQYIKNPYNIFDGIIVVISVWE-IIGQSDGG--------LSVLRTFRLLRVLKLVRFMPALRRQLVVLVKTMDNVATFCMLLMLFIFIFSILGMHLFGCKFTWTADTGETVKDRKNFDSLLWAIVTVFQILTQEDWNMVLYNGM 905 HSP 8 Score: 74.3294 bits (181), Expect = 2.830e-12 Identity = 64/281 (22.78%), Postives = 133/281 (47.33%), Query Frame = 1 Query: 2149 ICQQKIKTLVNDVKFQRGILIAILINTLSMGIEYHQ-QPVQLTQT-LEFSNIVFSILFLIEMILKLIGEGILG----YIKNGFNLFDGIIVVLGVIELCQQGGTSGLSILRTFRLLRILKL-------VRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKFCTIEN-------NKRTCDRK---------NFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTSS----------WAALYFIALMTFGNYVLFNLLVAILVEGFSSER 2874 +CQ+ I + F +L+ I +N +++ +E P L + L SN +F+ +F++EM +K++ G + Y+++ +N+ DGI+V + +I++ ++G + + + L + P L+ + +I ++ + + F IF ILG+ LF KF E N+ C R NFD+L +++++F + +++ W ++Y+G+ ++ W LYFI+ + ++ + N+ V ++VE F R Sbjct: 1194 MCQKVIAHKM----FDHVVLVFIFLNCITIALERPDIDPNSLERIFLSVSNYIFTAIFVLEMAIKVVALGFVSGENTYLQSSWNVLDGILVFVSIIDIVVSLASAGGAKILGVLRVLRLLRTLRPLRVISRAPGLKLVVETLISSLRPIGNIVLICCAFFIIFGILGVQLFKGKFYYCEGLETRNITNRSECTRARYKWVRRKYNFDNLGQALMSLFVLSSKDGWVNIMYDGLDAVATDVQPVKNHNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHKCR 1470 HSP 9 Score: 62.7734 bits (151), Expect = 9.931e-9 Identity = 37/117 (31.62%), Postives = 62/117 (52.99%), Query Frame = 1 Query: 337 FHIFHQNKHPRDWCLKIITWPWFEQLSMTIIAVNCITLSMYQPCGDQNCETSKCQIMQAFDYIIFAFFTCEMVIKIIAMGFL-GDLGYFGDTWNRLDMFIVIVGSIEILPSTGNNIG 684 ++F R C K+I F+ + + I +NCIT+++ +P D N + + + +YI A F EM IK++A+GF+ G+ Y +WN LD +V V I+I+ S + G Sbjct: 1182 LYMFSPQNQFRMMCQKVIAHKMFDHVVLVFIFLNCITIALERPDIDPN--SLERIFLSVSNYIFTAIFVLEMAIKVVALGFVSGENTYLQSSWNVLDGILVFVSIIDIVVSLASAGG 1296 HSP 10 Score: 54.299 bits (129), Expect = 2.940e-6 Identity = 26/80 (32.50%), Postives = 48/80 (60.00%), Query Frame = 1 Query: 1195 NFDNIGFAWVAIFQVISMESWVDIMYYVQDA----------HSFWDWIYFVALIIIGSFFMINLCLVVIASQFSETKRRE 1404 NFDN+G A +++F + S + WV+IMY DA H+ W +YF++ ++I SFF++N+ + V+ F + ++ + Sbjct: 1394 NFDNLGQALMSLFVLSSKDGWVNIMYDGLDAVATDVQPVKNHNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHKCRQHQ 1473 HSP 11 Score: 53.5286 bits (127), Expect = 5.663e-6 Identity = 23/78 (29.49%), Postives = 45/78 (57.69%), Query Frame = 1 Query: 2674 NFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTSSWAALYFIALMTFGNYVLFNLLVAILVEGFSSERLDEQKLLHNYR 2907 NFD++ ++ + +FQ++T E W ++Y M S + +YFI L+ G++ + NL + ++ FS + E +L+ R Sbjct: 337 NFDNIGYAWIAIFQVITLEGWVDIMYYVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQRENQLMQEQR 414
BLAST of Voltage-dependent T-type calcium channel subunit alpha vs. Ensembl Mouse
Match: Cacna1h (calcium channel, voltage-dependent, T type, alpha 1H subunit [Source:MGI Symbol;Acc:MGI:1928842]) HSP 1 Score: 651.744 bits (1680), Expect = 0.000e+0 Identity = 399/646 (61.76%), Postives = 497/646 (76.93%), Query Frame = 1 Query: 3814 AKRYYHSLYVFSVDNQFRQKCQHIVDKKSFDYLVLFFITLNCITLAMERPSIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKFYYCDGPHLQAVKTKNDCLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFHKCQENQXXXXXXXXXXXXXXXXXXXXXHLRAPLYWENYSKWRRTINSVVTSKYFDLAIAGVIGLNVITMATEFHMMPQVLKTALKVFNYFFTSTFVXXXXXXXXXXXXXRYISDKWNQLDMMIVILSIAGVVIDEVESN-FMPINPTIMRVMRVLRIARVLKLLKMASGIRALLDTVIQALPQVGNXXXXXXXXXXXXXXXXVELFGRLECSDINPCVGLGRHAHFENFGMAFLTLFRIATGDNWNGIMKDTLREKCISSEDCQRNCCVSAI--IAPIYFVIFXXXXXXXXXXXXXXXXXKHLEESHKMMCDDYELEREVQRDLDE----EAKELAREKQLKDEENNENTLI 5730 + R +LY+F N+ R CQ ++ K FD++VL FI LNCIT+A+ERP I P S ER FL+V+NYIFT IF EM++KV++ GLL G+ AYL+S WN++DG LV +SL+D+ + + +I G+LRV RLLRTLRPLRVISRAPGLKLVV+TL+SSLRPIGNIVLICC FFIIFGILGVQLFKGKFYYC+G + + TK +C + W +KYNFDNLGQALM+LFVLSSKDGWV IMY G+DAVG++ QP +NHN W L+YFISFLL+V+FFVLNMFVGVVVENFHKC+++QE EE RR KR RRLE++R+ + Y+ +YS RR+I+S+ TS Y DL I +I LNVITM+ E + P+ L ALK NY FT FV EA LKLVA G R+ D+WNQLD+ IV+LSI G+ ++E+E N +PINPTI+R+MRVLRIARVLKLLKMA+G+RALLDTV+QALPQVGNLGLLF LLF+I+AALGVELFGRLECS+ NPC GL RHA F NFGMAFLTLFR++TGDNWNGIMKDTLRE + ED C+S + ++P+YFV FVL+AQFVLVNVVVAVLMKHLEES+K +D E++ E++ ++ + + A+E Q E + N L+ Sbjct: 1278 SSRESWALYLFPPQNRLRVSCQKVIAHKMFDHVVLVFIFLNCITIALERPDIDPGSTERAFLSVSNYIFTAIFVVEMMVKVVALGLLWGEHAYLQSSWNVLDGLLVLVSLVDIIVAVASAGGAKILGVLRVLRLLRTLRPLRVISRAPGLKLVVETLISSLRPIGNIVLICCAFFIIFGILGVQLFKGKFYYCEGTDTRNITTKAEC-HAAHYRWVRRKYNFDNLGQALMSLFVLSSKDGWVNIMYDGLDAVGIDQQPVQNHNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHKCRQHQEAEEARRREEKRLRRLERRRRKAQRRPYYADYSHTRRSIHSLCTSHYLDLFITFIICLNVITMSMEHYNQPKSLDEALKYCNYVFTIVFVFEAALKLVAFGFRRFFKDRWNQLDLAIVLLSIMGIALEEIEMNAALPINPTIIRIMRVLRIARVLKLLKMATGMRALLDTVVQALPQVGNLGLLFMLLFFIYAALGVELFGRLECSEDNPCEGLSRHATFTNFGMAFLTLFRVSTGDNWNGIMKDTLRE--CTREDKH---CLSYLPALSPVYFVTFVLVAQFVLVNVVVAVLMKHLEESNKEAREDAEMDAEIELEIAQGSTAQPPSTAQESQ-GTEPDTPNLLV 1916 HSP 2 Score: 377.096 bits (967), Expect = 7.836e-105 Identity = 241/469 (51.39%), Postives = 312/469 (66.52%), Query Frame = 1 Query: 199 RETLIGNKSDFNLTDKSKADHCQQETDGTPINPNESLIYHGFYATVFHIFHQNKHPRDWCLKIITWPWFEQLSMTIIAVNCITLSMYQPCGDQNCETSKCQIMQAFDYIIFAFFTCEMVIKIIAMGFLGDLGYFGDTWNRLDMFIVIVGSIEILPSTGNNIGLTAIRTIRVLRPLRAINRIPSMRIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQMWQGVLRNRCYL------NLNESFRHPGLNLSSFYQINRTLFLNAVDKDFICSTDKNNGILKCSDIPPSIMLLSNNSL--QICKQPARPFTDNLPTKHSCVNWNQYYTDCQPGEKNPYEGAINFDNIGFAWVAIFQVISMESWVDIMYYVQDAHSFWDWIYFVALIIIGSFFMINLCLVVIASQFSETKRRETERMWIERRRFNSSNCSSISKDEPQTCYLEXXXXXXXXXXXXYRRIVKLYNQIQIRHSK 1581 RE G+ S L +S C + P + Y ATVF Q PR WCL+++ PWFE +SM +I +NC+TL M++PC D C + +C I++AFD IFAFF EMVIK++A+G G Y GDTWNRLD FIV+ G +E G+N+ L+AIRT+RVLRPLRAINR+PSMRILV LLLDTLPMLGNVLLLCFFVFFIFGI+GVQ+W G+LRNRC+L N N +F P +YQ + FICS+ ++NG+ KCS IP L +L + QP D +++C+NWNQYY C+ GE NP+ GAINFDNIG+AW+AIFQVI++E WVDIMYYV DAHSF+++IYF+ LII+GSFFMINLCLVVIA+QFSETK+RE + M +R R+ S++ + S EP +CY E++K + I K+ RR ++LY + Q R K Sbjct: 38 REEQRGSGSSV-LAPESPGTECGADLGADEEQP---VPYPALAATVFFCLGQTTRPRSWCLRLVCNPWFEHISMLVIMLNCVTLGMFRPCEDVECRSERCSILEAFDDFIFAFFAVEMVIKMVALGLFGQKCYLGDTWNRLDFFIVMAGMME-YSLDGHNVSLSAIRTVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAGLLRNRCFLDSAFVRNNNLTFLRP------YYQTE-----EGEENPFICSSRRDNGMQKCSHIPSRRELRVQCTLGWEAYGQPQA--EDGGAGRNACINWNQYYNVCRSGEFNPHNGAINFDNIGYAWIAIFQVITLEGWVDIMYYVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQRENQLMREQRARYLSNDSTLASFSEPGSCYEELLKYVGHIFRKVKRRSLRLYARWQSRWRK 488 HSP 3 Score: 337.806 bits (865), Expect = 1.066e-92 Identity = 190/324 (58.64%), Postives = 234/324 (72.22%), Query Frame = 1 Query: 2161 KIKTLVNDVKFQRGILIAILINTLSMGIEYHQQPVQLTQTLEFSNIVFSILFLIEMILKLIGEGILGYIKNGFNLFDGIIVVLGVIELCQQGGTSGLSILRTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKFCTIENNKRTC-DRKNFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTSSWAALYFIALMTFGNYVLFNLLVAILVEGFSSER------LDEQKLLHNYRQSLKKRRANNKQLRIMQHQSENLVLLTNSIQKDQTGENQKISSQPPVIIHTAATPMPTPRSSPYNELV 3111 K++ +V+ F RGI+ AIL+NTLSMG+EYH+QP +LT LE SNIVF+ +F +EM+LKL+ G LGYI+N +N+FDGI+V++ V E+ Q GLS+LRTFRLLR+LKLVRF+PALR+QL V++RT+DNVATF LL+LFIFIFSILGM LFGCKF ++ T DRKNFDSLLW+IVTVFQILTQEDWN VLYNGM TSSWAALYF+ALMTFGNYVLFNLLVAILVEGF +E DE K + + K LR +Q + L + G S PP+I HTAATPMPTP+SSP+ ++ Sbjct: 782 KLRRIVDSKYFNRGIMAAILVNTLSMGVEYHEQPDELTNALEISNIVFTSMFALEMLLKLLACGPLGYIRNPYNIFDGIVVIISVWEIVGQA-DGGLSVLRTFRLLRVLKLVRFLPALRRQLVVLMRTMDNVATFCMLLMLFIFIFSILGMHLFGCKFSLKTDSGDTVPDRKNFDSLLWAIVTVFQILTQEDWNVVLYNGMASTSSWAALYFVALMTFGNYVLFNLLVAILVEGFQAEGDATRSDTDEDKTSTHLEEDFDK-------LRDVQATEMKMYSLAVTPNGHLEGRG---SLPPPLITHTAATPMPTPKSSPHLDMA 1094 HSP 4 Score: 114.39 bits (285), Expect = 1.586e-24 Identity = 73/278 (26.26%), Postives = 138/278 (49.64%), Query Frame = 1 Query: 3862 FRQKCQHIVDKKSFDYLVLFFITLNCITLAMERPSIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKFYYCDGPHLQAVKTKNDCLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFH 4695 F K + IVD K F+ ++ I +N +++ +E P L ++N +FT +F EM++K+L+ G L Y+++ +NI DG +V IS+ + ++G ++ +LR FRLLR L+ +R + P L+ + L+ ++ + ++ F IF ILG+ LF KF LK + + NFD+L A++ +F + +++ W ++Y G+ + + WA +YF++ + + + N+ V ++VE F Sbjct: 779 FSSKLRRIVDSKYFNRGIMAAILVNTLSMGVEYHEQPDELTNAL--EISNIVFTSMFALEMLLKLLACGPL----GYIRNPYNIFDGIVVIISVWE-----IVGQADGGLSVLRTFRLLRVLKLVRFL---PALRRQLVVLMRTMDNVATFCMLLMLFIFIFSILGMHLFGCKF----------------SLKTDSGDTVPDRKNFDSLLWAIVTVFQILTQEDWNVVLYNGMAST----------SSWAALYFVALMTFGNYVLFNLLVAILVEGFQ 1016 HSP 5 Score: 82.8037 bits (203), Expect = 5.314e-15 Identity = 64/247 (25.91%), Postives = 121/247 (48.99%), Query Frame = 1 Query: 2101 PFNKNQNKTKRKNYLSICQQKIKTLVNDVKFQRGILIAILINTLSMGIEYHQQPVQLTQTLEFSNIVFSILFLIEMILKLIGEGILGYIKNGFNLFDGIIVVLGVIELCQQG---------GTSGLSILRTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKFCTIENNKRTCDR-KNFDSLLWSIVTVFQILTQEDWNTVLYNGM---TRTSSWAALYFIAL 2802 P+ + + T+R + S+C L I I +N ++M +E++ QP L + L++ N VF+I+F+ E LKL+ G + K+ +N D IV+L ++ + + + + I+R R+ R+LKL++ +R L +++ + V L +L FI++ LG+ LFG C+ +N R F + + +T+F++ T ++WN ++ + + TR Y AL Sbjct: 1603 PYYADYSHTRRSIH-SLCTSHYLDLF--------ITFIICLNVITMSMEHYNQPKSLDEALKYCNYVFTIVFVFEAALKLVAFGFRRFFKDRWNQLDLAIVLLSIMGIALEEIEMNAALPINPTIIRIMRVLRIARVLKLLKMATGMRALLDTVVQALPQVGNLGLLFMLLFFIYAALGVELFGRLECSEDNPCEGLSRHATFTNFGMAFLTLFRVSTGDNWNGIMKDTLRECTREDKHCLSYLPAL 1840 HSP 6 Score: 82.0333 bits (201), Expect = 9.177e-15 Identity = 61/173 (35.26%), Postives = 96/173 (55.49%), Query Frame = 1 Query: 3865 RQKCQHIVDKKSFDYLVLFFITLNCITLAMERP--SIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKG 4377 R C +V F+++ + I LNC+TL M RP + S+ L + F EM+IK+++ GL G + YL WN +D F+V +++ + GH+ + I R +R LRPLR I+R P ++++V LL +L +GN++L+C F IFGI+GVQL+ G Sbjct: 90 RSWCLRLVCNPWFEHISMLVIMLNCVTLGMFRPCEDVECRSERCSILEAFDDFIFAFFAVEMVIKMVALGLF-GQKCYLGDTWNRLDFFIVMAGMMEYSLD---GHNVSLSAI----RTVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAG 254 HSP 7 Score: 75.0998 bits (183), Expect = 1.308e-12 Identity = 71/224 (31.70%), Postives = 119/224 (53.12%), Query Frame = 1 Query: 4798 WENYS-KWRRTINSVVTSKYFDLAIAGVIGLNVITMATEFHMMPQVLKTALKVFNYFFTSTFVXXXXXXXXXXXXXRYISDKWNQLDMMIVILSIAGVVIDEVESNFMPINPTIMRVMRVLRIARVLKLLKMASGIRALLDTVIQALPQVGNXXXXXXXXXXXXXXXXVELFG-----RLECSDINPCVGLGRHAHFENFGMAFLTLFRIATGDNWNGIMKDTL 5451 W ++S K RR +V SKYF+ I I +N ++M E+H P L AL++ N FTS F LE LLKL+A G YI + +N D ++VI+S+ +V + + + V+R R+ RVLKL++ +R L +++ + V +L L +IF+ LG+ LFG + + D P +F++ A +T+F+I T ++WN ++ + + Sbjct: 776 WASFSSKLRR----IVDSKYFNRGIMAAILVNTLSMGVEYHEQPDELTNALEISNIVFTSMFALEMLLKLLACGPLGYIRNPYNIFDGIVVIISVWEIV-GQADGG--------LSVLRTFRLLRVLKLVRFLPALRRQLVVLMRTMDNVATFCMLLMLFIFIFSILGMHLFGCKFSLKTDSGDTVP-----DRKNFDSLLWAIVTVFQILTQEDWNVVLYNGM 981 HSP 8 Score: 70.4774 bits (171), Expect = 3.085e-11 Identity = 65/282 (23.05%), Postives = 138/282 (48.94%), Query Frame = 1 Query: 2134 KNYLSICQQKIKTLVNDVKFQRGILIAILINTLSMGIEYHQQPVQLTQT--LEFSNIVFSILFLIEMILKLIGEGIL----GYIKNGFNLFDGIIVVLGVIELCQQGGTSGLSIL-------RTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKFCTIEN-------NKRTCD---------RKNFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTS----------SWAALYFIALMTFGNYVLFNLLVAILVEGF 2862 +N L + QK+ + F +L+ I +N +++ +E T+ L SN +F+ +F++EM++K++ G+L Y+++ +N+ DG++V++ ++++ ++G + + R R LR L+++ P L+ + +I ++ + + F IF ILG+ LF KF E K C + NFD+L +++++F + +++ W ++Y+G+ W LYFI+ + ++ + N+ V ++VE F Sbjct: 1291 QNRLRVSCQKV---IAHKMFDHVVLVFIFLNCITIALERPDIDPGSTERAFLSVSNYIFTAIFVVEMMVKVVALGLLWGEHAYLQSSWNVLDGLLVLVSLVDIIVAVASAGGAKILGVLRVLRLLRTLRPLRVISRAPGLKLVVETLISSLRPIGNIVLICCAFFIIFGILGVQLFKGKFYYCEGTDTRNITTKAECHAAHYRWVRRKYNFDNLGQALMSLFVLSSKDGWVNIMYDGLDAVGIDQQPVQNHNPWMLLYFISFLLIVSFFVLNMFVGVVVENF 1569 HSP 9 Score: 63.929 bits (154), Expect = 2.676e-9 Identity = 33/118 (27.97%), Postives = 64/118 (54.24%), Query Frame = 1 Query: 334 VFHIFHQNKHPRDWCLKIITWPWFEQLSMTIIAVNCITLSMYQPCGDQNCETSKCQIMQAFDYIIFAFFTCEMVIKIIAMGFL-GDLGYFGDTWNRLDMFIVIVGSIEILPSTGNNIG 684 ++F R C K+I F+ + + I +NCIT+++ +P D + +++ + +YI A F EM++K++A+G L G+ Y +WN LD +V+V ++I+ + + G Sbjct: 1284 ALYLFPPQNRLRVSCQKVIAHKMFDHVVLVFIFLNCITIALERP--DIDPGSTERAFLSVSNYIFTAIFVVEMMVKVVALGLLWGEHAYLQSSWNVLDGLLVLVSLVDIIVAVASAGG 1399 HSP 10 Score: 55.8398 bits (133), Expect = 9.279e-7 Identity = 31/86 (36.05%), Postives = 50/86 (58.14%), Query Frame = 1 Query: 4462 NQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFH--KCQENQ 4713 N NFDN+G A +A+F + + +GWV IMY +DA H+ + IYFI +++ +FF++N+ + V+ F K +ENQ Sbjct: 356 NGAINFDNIGYAWIAIFQVITLEGWVDIMYYVMDA----------HSFYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQRENQ 431 HSP 11 Score: 54.6842 bits (130), Expect = 1.848e-6 Identity = 26/80 (32.50%), Postives = 48/80 (60.00%), Query Frame = 1 Query: 1195 NFDNIGFAWVAIFQVISMESWVDIMYYVQDA----------HSFWDWIYFVALIIIGSFFMINLCLVVIASQFSETKRRE 1404 NFDN+G A +++F + S + WV+IMY DA H+ W +YF++ ++I SFF++N+ + V+ F + ++ + Sbjct: 1497 NFDNLGQALMSLFVLSSKDGWVNIMYDGLDAVGIDQQPVQNHNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHKCRQHQ 1576 HSP 12 Score: 52.7582 bits (125), Expect = 7.150e-6 Identity = 23/75 (30.67%), Postives = 44/75 (58.67%), Query Frame = 1 Query: 1195 NFDNIGFAWVAIFQVISMESWVDIMYYVQDAHSFWDWIYFVALIIIGSFFMINLCLVVIASQF---SETKRRETE 1410 NFD++ +A V +FQ+++ E W ++Y + S W +YFVAL+ G++ + NL + ++ F + R +T+ Sbjct: 953 NFDSLLWAIVTVFQILTQEDWNVVLYNGMASTSSWAALYFVALMTFGNYVLFNLLVAILVEGFQAEGDATRSDTD 1027 HSP 13 Score: 52.373 bits (124), Expect = 8.821e-6 Identity = 23/78 (29.49%), Postives = 45/78 (57.69%), Query Frame = 1 Query: 2674 NFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTSSWAALYFIALMTFGNYVLFNLLVAILVEGFSSERLDEQKLLHNYR 2907 NFD++ ++ + +FQ++T E W ++Y M S + +YFI L+ G++ + NL + ++ FS + E +L+ R Sbjct: 360 NFDNIGYAWIAIFQVITLEGWVDIMYYVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQRENQLMREQR 437
BLAST of Voltage-dependent T-type calcium channel subunit alpha vs. Ensembl Mouse
Match: Cacna1h (calcium channel, voltage-dependent, T type, alpha 1H subunit [Source:MGI Symbol;Acc:MGI:1928842]) HSP 1 Score: 651.744 bits (1680), Expect = 0.000e+0 Identity = 399/646 (61.76%), Postives = 497/646 (76.93%), Query Frame = 1 Query: 3814 AKRYYHSLYVFSVDNQFRQKCQHIVDKKSFDYLVLFFITLNCITLAMERPSIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKFYYCDGPHLQAVKTKNDCLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFHKCQENQXXXXXXXXXXXXXXXXXXXXXHLRAPLYWENYSKWRRTINSVVTSKYFDLAIAGVIGLNVITMATEFHMMPQVLKTALKVFNYFFTSTFVXXXXXXXXXXXXXRYISDKWNQLDMMIVILSIAGVVIDEVESN-FMPINPTIMRVMRVLRIARVLKLLKMASGIRALLDTVIQALPQVGNXXXXXXXXXXXXXXXXVELFGRLECSDINPCVGLGRHAHFENFGMAFLTLFRIATGDNWNGIMKDTLREKCISSEDCQRNCCVSAI--IAPIYFVIFXXXXXXXXXXXXXXXXXKHLEESHKMMCDDYELEREVQRDLDE----EAKELAREKQLKDEENNENTLI 5730 + R +LY+F N+ R CQ ++ K FD++VL FI LNCIT+A+ERP I P S ER FL+V+NYIFT IF EM++KV++ GLL G+ AYL+S WN++DG LV +SL+D+ + + +I G+LRV RLLRTLRPLRVISRAPGLKLVV+TL+SSLRPIGNIVLICC FFIIFGILGVQLFKGKFYYC+G + + TK +C + W +KYNFDNLGQALM+LFVLSSKDGWV IMY G+DAVG++ QP +NHN W L+YFISFLL+V+FFVLNMFVGVVVENFHKC+++QE EE RR KR RRLE++R+ + Y+ +YS RR+I+S+ TS Y DL I +I LNVITM+ E + P+ L ALK NY FT FV EA LKLVA G R+ D+WNQLD+ IV+LSI G+ ++E+E N +PINPTI+R+MRVLRIARVLKLLKMA+G+RALLDTV+QALPQVGNLGLLF LLF+I+AALGVELFGRLECS+ NPC GL RHA F NFGMAFLTLFR++TGDNWNGIMKDTLRE + ED C+S + ++P+YFV FVL+AQFVLVNVVVAVLMKHLEES+K +D E++ E++ ++ + + A+E Q E + N L+ Sbjct: 1278 SSRESWALYLFPPQNRLRVSCQKVIAHKMFDHVVLVFIFLNCITIALERPDIDPGSTERAFLSVSNYIFTAIFVVEMMVKVVALGLLWGEHAYLQSSWNVLDGLLVLVSLVDIIVAVASAGGAKILGVLRVLRLLRTLRPLRVISRAPGLKLVVETLISSLRPIGNIVLICCAFFIIFGILGVQLFKGKFYYCEGTDTRNITTKAEC-HAAHYRWVRRKYNFDNLGQALMSLFVLSSKDGWVNIMYDGLDAVGIDQQPVQNHNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHKCRQHQEAEEARRREEKRLRRLERRRRKAQRRPYYADYSHTRRSIHSLCTSHYLDLFITFIICLNVITMSMEHYNQPKSLDEALKYCNYVFTIVFVFEAALKLVAFGFRRFFKDRWNQLDLAIVLLSIMGIALEEIEMNAALPINPTIIRIMRVLRIARVLKLLKMATGMRALLDTVVQALPQVGNLGLLFMLLFFIYAALGVELFGRLECSEDNPCEGLSRHATFTNFGMAFLTLFRVSTGDNWNGIMKDTLRE--CTREDKH---CLSYLPALSPVYFVTFVLVAQFVLVNVVVAVLMKHLEESNKEAREDAEMDAEIELEIAQGSTAQPPSTAQESQ-GTEPDTPNLLV 1916 HSP 2 Score: 377.096 bits (967), Expect = 7.836e-105 Identity = 241/469 (51.39%), Postives = 312/469 (66.52%), Query Frame = 1 Query: 199 RETLIGNKSDFNLTDKSKADHCQQETDGTPINPNESLIYHGFYATVFHIFHQNKHPRDWCLKIITWPWFEQLSMTIIAVNCITLSMYQPCGDQNCETSKCQIMQAFDYIIFAFFTCEMVIKIIAMGFLGDLGYFGDTWNRLDMFIVIVGSIEILPSTGNNIGLTAIRTIRVLRPLRAINRIPSMRIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQMWQGVLRNRCYL------NLNESFRHPGLNLSSFYQINRTLFLNAVDKDFICSTDKNNGILKCSDIPPSIMLLSNNSL--QICKQPARPFTDNLPTKHSCVNWNQYYTDCQPGEKNPYEGAINFDNIGFAWVAIFQVISMESWVDIMYYVQDAHSFWDWIYFVALIIIGSFFMINLCLVVIASQFSETKRRETERMWIERRRFNSSNCSSISKDEPQTCYLEXXXXXXXXXXXXYRRIVKLYNQIQIRHSK 1581 RE G+ S L +S C + P + Y ATVF Q PR WCL+++ PWFE +SM +I +NC+TL M++PC D C + +C I++AFD IFAFF EMVIK++A+G G Y GDTWNRLD FIV+ G +E G+N+ L+AIRT+RVLRPLRAINR+PSMRILV LLLDTLPMLGNVLLLCFFVFFIFGI+GVQ+W G+LRNRC+L N N +F P +YQ + FICS+ ++NG+ KCS IP L +L + QP D +++C+NWNQYY C+ GE NP+ GAINFDNIG+AW+AIFQVI++E WVDIMYYV DAHSF+++IYF+ LII+GSFFMINLCLVVIA+QFSETK+RE + M +R R+ S++ + S EP +CY E++K + I K+ RR ++LY + Q R K Sbjct: 38 REEQRGSGSSV-LAPESPGTECGADLGADEEQP---VPYPALAATVFFCLGQTTRPRSWCLRLVCNPWFEHISMLVIMLNCVTLGMFRPCEDVECRSERCSILEAFDDFIFAFFAVEMVIKMVALGLFGQKCYLGDTWNRLDFFIVMAGMME-YSLDGHNVSLSAIRTVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAGLLRNRCFLDSAFVRNNNLTFLRP------YYQTE-----EGEENPFICSSRRDNGMQKCSHIPSRRELRVQCTLGWEAYGQPQA--EDGGAGRNACINWNQYYNVCRSGEFNPHNGAINFDNIGYAWIAIFQVITLEGWVDIMYYVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQRENQLMREQRARYLSNDSTLASFSEPGSCYEELLKYVGHIFRKVKRRSLRLYARWQSRWRK 488 HSP 3 Score: 337.806 bits (865), Expect = 1.066e-92 Identity = 190/324 (58.64%), Postives = 234/324 (72.22%), Query Frame = 1 Query: 2161 KIKTLVNDVKFQRGILIAILINTLSMGIEYHQQPVQLTQTLEFSNIVFSILFLIEMILKLIGEGILGYIKNGFNLFDGIIVVLGVIELCQQGGTSGLSILRTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKFCTIENNKRTC-DRKNFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTSSWAALYFIALMTFGNYVLFNLLVAILVEGFSSER------LDEQKLLHNYRQSLKKRRANNKQLRIMQHQSENLVLLTNSIQKDQTGENQKISSQPPVIIHTAATPMPTPRSSPYNELV 3111 K++ +V+ F RGI+ AIL+NTLSMG+EYH+QP +LT LE SNIVF+ +F +EM+LKL+ G LGYI+N +N+FDGI+V++ V E+ Q GLS+LRTFRLLR+LKLVRF+PALR+QL V++RT+DNVATF LL+LFIFIFSILGM LFGCKF ++ T DRKNFDSLLW+IVTVFQILTQEDWN VLYNGM TSSWAALYF+ALMTFGNYVLFNLLVAILVEGF +E DE K + + K LR +Q + L + G S PP+I HTAATPMPTP+SSP+ ++ Sbjct: 782 KLRRIVDSKYFNRGIMAAILVNTLSMGVEYHEQPDELTNALEISNIVFTSMFALEMLLKLLACGPLGYIRNPYNIFDGIVVIISVWEIVGQA-DGGLSVLRTFRLLRVLKLVRFLPALRRQLVVLMRTMDNVATFCMLLMLFIFIFSILGMHLFGCKFSLKTDSGDTVPDRKNFDSLLWAIVTVFQILTQEDWNVVLYNGMASTSSWAALYFVALMTFGNYVLFNLLVAILVEGFQAEGDATRSDTDEDKTSTHLEEDFDK-------LRDVQATEMKMYSLAVTPNGHLEGRG---SLPPPLITHTAATPMPTPKSSPHLDMA 1094 HSP 4 Score: 114.39 bits (285), Expect = 1.586e-24 Identity = 73/278 (26.26%), Postives = 138/278 (49.64%), Query Frame = 1 Query: 3862 FRQKCQHIVDKKSFDYLVLFFITLNCITLAMERPSIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKFYYCDGPHLQAVKTKNDCLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFH 4695 F K + IVD K F+ ++ I +N +++ +E P L ++N +FT +F EM++K+L+ G L Y+++ +NI DG +V IS+ + ++G ++ +LR FRLLR L+ +R + P L+ + L+ ++ + ++ F IF ILG+ LF KF LK + + NFD+L A++ +F + +++ W ++Y G+ + + WA +YF++ + + + N+ V ++VE F Sbjct: 779 FSSKLRRIVDSKYFNRGIMAAILVNTLSMGVEYHEQPDELTNAL--EISNIVFTSMFALEMLLKLLACGPL----GYIRNPYNIFDGIVVIISVWE-----IVGQADGGLSVLRTFRLLRVLKLVRFL---PALRRQLVVLMRTMDNVATFCMLLMLFIFIFSILGMHLFGCKF----------------SLKTDSGDTVPDRKNFDSLLWAIVTVFQILTQEDWNVVLYNGMAST----------SSWAALYFVALMTFGNYVLFNLLVAILVEGFQ 1016 HSP 5 Score: 82.8037 bits (203), Expect = 5.314e-15 Identity = 64/247 (25.91%), Postives = 121/247 (48.99%), Query Frame = 1 Query: 2101 PFNKNQNKTKRKNYLSICQQKIKTLVNDVKFQRGILIAILINTLSMGIEYHQQPVQLTQTLEFSNIVFSILFLIEMILKLIGEGILGYIKNGFNLFDGIIVVLGVIELCQQG---------GTSGLSILRTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKFCTIENNKRTCDR-KNFDSLLWSIVTVFQILTQEDWNTVLYNGM---TRTSSWAALYFIAL 2802 P+ + + T+R + S+C L I I +N ++M +E++ QP L + L++ N VF+I+F+ E LKL+ G + K+ +N D IV+L ++ + + + + I+R R+ R+LKL++ +R L +++ + V L +L FI++ LG+ LFG C+ +N R F + + +T+F++ T ++WN ++ + + TR Y AL Sbjct: 1603 PYYADYSHTRRSIH-SLCTSHYLDLF--------ITFIICLNVITMSMEHYNQPKSLDEALKYCNYVFTIVFVFEAALKLVAFGFRRFFKDRWNQLDLAIVLLSIMGIALEEIEMNAALPINPTIIRIMRVLRIARVLKLLKMATGMRALLDTVVQALPQVGNLGLLFMLLFFIYAALGVELFGRLECSEDNPCEGLSRHATFTNFGMAFLTLFRVSTGDNWNGIMKDTLRECTREDKHCLSYLPAL 1840 HSP 6 Score: 82.0333 bits (201), Expect = 9.177e-15 Identity = 61/173 (35.26%), Postives = 96/173 (55.49%), Query Frame = 1 Query: 3865 RQKCQHIVDKKSFDYLVLFFITLNCITLAMERP--SIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKG 4377 R C +V F+++ + I LNC+TL M RP + S+ L + F EM+IK+++ GL G + YL WN +D F+V +++ + GH+ + I R +R LRPLR I+R P ++++V LL +L +GN++L+C F IFGI+GVQL+ G Sbjct: 90 RSWCLRLVCNPWFEHISMLVIMLNCVTLGMFRPCEDVECRSERCSILEAFDDFIFAFFAVEMVIKMVALGLF-GQKCYLGDTWNRLDFFIVMAGMMEYSLD---GHNVSLSAI----RTVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAG 254 HSP 7 Score: 75.0998 bits (183), Expect = 1.308e-12 Identity = 71/224 (31.70%), Postives = 119/224 (53.12%), Query Frame = 1 Query: 4798 WENYS-KWRRTINSVVTSKYFDLAIAGVIGLNVITMATEFHMMPQVLKTALKVFNYFFTSTFVXXXXXXXXXXXXXRYISDKWNQLDMMIVILSIAGVVIDEVESNFMPINPTIMRVMRVLRIARVLKLLKMASGIRALLDTVIQALPQVGNXXXXXXXXXXXXXXXXVELFG-----RLECSDINPCVGLGRHAHFENFGMAFLTLFRIATGDNWNGIMKDTL 5451 W ++S K RR +V SKYF+ I I +N ++M E+H P L AL++ N FTS F LE LLKL+A G YI + +N D ++VI+S+ +V + + + V+R R+ RVLKL++ +R L +++ + V +L L +IF+ LG+ LFG + + D P +F++ A +T+F+I T ++WN ++ + + Sbjct: 776 WASFSSKLRR----IVDSKYFNRGIMAAILVNTLSMGVEYHEQPDELTNALEISNIVFTSMFALEMLLKLLACGPLGYIRNPYNIFDGIVVIISVWEIV-GQADGG--------LSVLRTFRLLRVLKLVRFLPALRRQLVVLMRTMDNVATFCMLLMLFIFIFSILGMHLFGCKFSLKTDSGDTVP-----DRKNFDSLLWAIVTVFQILTQEDWNVVLYNGM 981 HSP 8 Score: 70.4774 bits (171), Expect = 3.085e-11 Identity = 65/282 (23.05%), Postives = 138/282 (48.94%), Query Frame = 1 Query: 2134 KNYLSICQQKIKTLVNDVKFQRGILIAILINTLSMGIEYHQQPVQLTQT--LEFSNIVFSILFLIEMILKLIGEGIL----GYIKNGFNLFDGIIVVLGVIELCQQGGTSGLSIL-------RTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKFCTIEN-------NKRTCD---------RKNFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTS----------SWAALYFIALMTFGNYVLFNLLVAILVEGF 2862 +N L + QK+ + F +L+ I +N +++ +E T+ L SN +F+ +F++EM++K++ G+L Y+++ +N+ DG++V++ ++++ ++G + + R R LR L+++ P L+ + +I ++ + + F IF ILG+ LF KF E K C + NFD+L +++++F + +++ W ++Y+G+ W LYFI+ + ++ + N+ V ++VE F Sbjct: 1291 QNRLRVSCQKV---IAHKMFDHVVLVFIFLNCITIALERPDIDPGSTERAFLSVSNYIFTAIFVVEMMVKVVALGLLWGEHAYLQSSWNVLDGLLVLVSLVDIIVAVASAGGAKILGVLRVLRLLRTLRPLRVISRAPGLKLVVETLISSLRPIGNIVLICCAFFIIFGILGVQLFKGKFYYCEGTDTRNITTKAECHAAHYRWVRRKYNFDNLGQALMSLFVLSSKDGWVNIMYDGLDAVGIDQQPVQNHNPWMLLYFISFLLIVSFFVLNMFVGVVVENF 1569 HSP 9 Score: 63.929 bits (154), Expect = 2.676e-9 Identity = 33/118 (27.97%), Postives = 64/118 (54.24%), Query Frame = 1 Query: 334 VFHIFHQNKHPRDWCLKIITWPWFEQLSMTIIAVNCITLSMYQPCGDQNCETSKCQIMQAFDYIIFAFFTCEMVIKIIAMGFL-GDLGYFGDTWNRLDMFIVIVGSIEILPSTGNNIG 684 ++F R C K+I F+ + + I +NCIT+++ +P D + +++ + +YI A F EM++K++A+G L G+ Y +WN LD +V+V ++I+ + + G Sbjct: 1284 ALYLFPPQNRLRVSCQKVIAHKMFDHVVLVFIFLNCITIALERP--DIDPGSTERAFLSVSNYIFTAIFVVEMMVKVVALGLLWGEHAYLQSSWNVLDGLLVLVSLVDIIVAVASAGG 1399 HSP 10 Score: 55.8398 bits (133), Expect = 9.279e-7 Identity = 31/86 (36.05%), Postives = 50/86 (58.14%), Query Frame = 1 Query: 4462 NQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFH--KCQENQ 4713 N NFDN+G A +A+F + + +GWV IMY +DA H+ + IYFI +++ +FF++N+ + V+ F K +ENQ Sbjct: 356 NGAINFDNIGYAWIAIFQVITLEGWVDIMYYVMDA----------HSFYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQRENQ 431 HSP 11 Score: 54.6842 bits (130), Expect = 1.848e-6 Identity = 26/80 (32.50%), Postives = 48/80 (60.00%), Query Frame = 1 Query: 1195 NFDNIGFAWVAIFQVISMESWVDIMYYVQDA----------HSFWDWIYFVALIIIGSFFMINLCLVVIASQFSETKRRE 1404 NFDN+G A +++F + S + WV+IMY DA H+ W +YF++ ++I SFF++N+ + V+ F + ++ + Sbjct: 1497 NFDNLGQALMSLFVLSSKDGWVNIMYDGLDAVGIDQQPVQNHNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHKCRQHQ 1576 HSP 12 Score: 52.7582 bits (125), Expect = 7.150e-6 Identity = 23/75 (30.67%), Postives = 44/75 (58.67%), Query Frame = 1 Query: 1195 NFDNIGFAWVAIFQVISMESWVDIMYYVQDAHSFWDWIYFVALIIIGSFFMINLCLVVIASQF---SETKRRETE 1410 NFD++ +A V +FQ+++ E W ++Y + S W +YFVAL+ G++ + NL + ++ F + R +T+ Sbjct: 953 NFDSLLWAIVTVFQILTQEDWNVVLYNGMASTSSWAALYFVALMTFGNYVLFNLLVAILVEGFQAEGDATRSDTD 1027 HSP 13 Score: 52.373 bits (124), Expect = 8.821e-6 Identity = 23/78 (29.49%), Postives = 45/78 (57.69%), Query Frame = 1 Query: 2674 NFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTSSWAALYFIALMTFGNYVLFNLLVAILVEGFSSERLDEQKLLHNYR 2907 NFD++ ++ + +FQ++T E W ++Y M S + +YFI L+ G++ + NL + ++ FS + E +L+ R Sbjct: 360 NFDNIGYAWIAIFQVITLEGWVDIMYYVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQRENQLMREQR 437
BLAST of Voltage-dependent T-type calcium channel subunit alpha vs. Ensembl Mouse
Match: Cacna1h (calcium channel, voltage-dependent, T type, alpha 1H subunit [Source:MGI Symbol;Acc:MGI:1928842]) HSP 1 Score: 648.662 bits (1672), Expect = 0.000e+0 Identity = 399/646 (61.76%), Postives = 497/646 (76.93%), Query Frame = 1 Query: 3814 AKRYYHSLYVFSVDNQFRQKCQHIVDKKSFDYLVLFFITLNCITLAMERPSIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKFYYCDGPHLQAVKTKNDCLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFHKCQENQXXXXXXXXXXXXXXXXXXXXXHLRAPLYWENYSKWRRTINSVVTSKYFDLAIAGVIGLNVITMATEFHMMPQVLKTALKVFNYFFTSTFVXXXXXXXXXXXXXRYISDKWNQLDMMIVILSIAGVVIDEVESN-FMPINPTIMRVMRVLRIARVLKLLKMASGIRALLDTVIQALPQVGNXXXXXXXXXXXXXXXXVELFGRLECSDINPCVGLGRHAHFENFGMAFLTLFRIATGDNWNGIMKDTLREKCISSEDCQRNCCVSAI--IAPIYFVIFXXXXXXXXXXXXXXXXXKHLEESHKMMCDDYELEREVQRDLDE----EAKELAREKQLKDEENNENTLI 5730 + R +LY+F N+ R CQ ++ K FD++VL FI LNCIT+A+ERP I P S ER FL+V+NYIFT IF EM++KV++ GLL G+ AYL+S WN++DG LV +SL+D+ + + +I G+LRV RLLRTLRPLRVISRAPGLKLVV+TL+SSLRPIGNIVLICC FFIIFGILGVQLFKGKFYYC+G + + TK +C + W +KYNFDNLGQALM+LFVLSSKDGWV IMY G+DAVG++ QP +NHN W L+YFISFLL+V+FFVLNMFVGVVVENFHKC+++QE EE RR KR RRLE++R+ + Y+ +YS RR+I+S+ TS Y DL I +I LNVITM+ E + P+ L ALK NY FT FV EA LKLVA G R+ D+WNQLD+ IV+LSI G+ ++E+E N +PINPTI+R+MRVLRIARVLKLLKMA+G+RALLDTV+QALPQVGNLGLLF LLF+I+AALGVELFGRLECS+ NPC GL RHA F NFGMAFLTLFR++TGDNWNGIMKDTLRE + ED C+S + ++P+YFV FVL+AQFVLVNVVVAVLMKHLEES+K +D E++ E++ ++ + + A+E Q E + N L+ Sbjct: 1172 SSRESWALYLFPPQNRLRVSCQKVIAHKMFDHVVLVFIFLNCITIALERPDIDPGSTERAFLSVSNYIFTAIFVVEMMVKVVALGLLWGEHAYLQSSWNVLDGLLVLVSLVDIIVAVASAGGAKILGVLRVLRLLRTLRPLRVISRAPGLKLVVETLISSLRPIGNIVLICCAFFIIFGILGVQLFKGKFYYCEGTDTRNITTKAEC-HAAHYRWVRRKYNFDNLGQALMSLFVLSSKDGWVNIMYDGLDAVGIDQQPVQNHNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHKCRQHQEAEEARRREEKRLRRLERRRRKAQRRPYYADYSHTRRSIHSLCTSHYLDLFITFIICLNVITMSMEHYNQPKSLDEALKYCNYVFTIVFVFEAALKLVAFGFRRFFKDRWNQLDLAIVLLSIMGIALEEIEMNAALPINPTIIRIMRVLRIARVLKLLKMATGMRALLDTVVQALPQVGNLGLLFMLLFFIYAALGVELFGRLECSEDNPCEGLSRHATFTNFGMAFLTLFRVSTGDNWNGIMKDTLRE--CTREDKH---CLSYLPALSPVYFVTFVLVAQFVLVNVVVAVLMKHLEESNKEAREDAEMDAEIELEIAQGSTAQPPSTAQESQ-GTEPDTPNLLV 1810 HSP 2 Score: 337.035 bits (863), Expect = 1.189e-92 Identity = 217/396 (54.80%), Postives = 280/396 (70.71%), Query Frame = 1 Query: 418 MTIIAVNCITLSMYQPCGDQNCETSKCQIMQAFDYIIFAFFTCEMVIKIIAMGFLGDLGYFGDTWNRLDMFIVIVGSIEILPSTGNNIGLTAIRTIRVLRPLRAINRIPSMRIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQMWQGVLRNRCYL------NLNESFRHPGLNLSSFYQINRTLFLNAVDKDFICSTDKNNGILKCSDIPPSIMLLSNNSL--QICKQPARPFTDNLPTKHSCVNWNQYYTDCQPGEKNPYEGAINFDNIGFAWVAIFQVISMESWVDIMYYVQDAHSFWDWIYFVALIIIGSFFMINLCLVVIASQFSETKRRETERMWIERRRFNSSNCSSISKDEPQTCYLEXXXXXXXXXXXXYRRIVKLYNQIQIRHSK 1581 M +I +NC+TL M++PC D C + +C I++AFD IFAFF EMVIK++A+G G Y GDTWNRLD FIV+ G +E G+N+ L+AIRT+RVLRPLRAINR+PSMRILV LLLDTLPMLGNVLLLCFFVFFIFGI+GVQ+W G+LRNRC+L N N +F P +YQ + FICS+ ++NG+ KCS IP L +L + QP D +++C+NWNQYY C+ GE NP+ GAINFDNIG+AW+AIFQVI++E WVDIMYYV DAHSF+++IYF+ LII+GSFFMINLCLVVIA+QFSETK+RE + M +R R+ S++ + S EP +CY E++K + I K+ RR ++LY + Q R K Sbjct: 1 MLVIMLNCVTLGMFRPCEDVECRSERCSILEAFDDFIFAFFAVEMVIKMVALGLFGQKCYLGDTWNRLDFFIVMAGMME-YSLDGHNVSLSAIRTVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAGLLRNRCFLDSAFVRNNNLTFLRP------YYQTE-----EGEENPFICSSRRDNGMQKCSHIPSRRELRVQCTLGWEAYGQPQA--EDGGAGRNACINWNQYYNVCRSGEFNPHNGAINFDNIGYAWIAIFQVITLEGWVDIMYYVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQRENQLMREQRARYLSNDSTLASFSEPGSCYEELLKYVGHIFRKVKRRSLRLYARWQSRWRK 382 HSP 3 Score: 335.88 bits (860), Expect = 2.170e-92 Identity = 190/324 (58.64%), Postives = 234/324 (72.22%), Query Frame = 1 Query: 2161 KIKTLVNDVKFQRGILIAILINTLSMGIEYHQQPVQLTQTLEFSNIVFSILFLIEMILKLIGEGILGYIKNGFNLFDGIIVVLGVIELCQQGGTSGLSILRTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKFCTIENNKRTC-DRKNFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTSSWAALYFIALMTFGNYVLFNLLVAILVEGFSSER------LDEQKLLHNYRQSLKKRRANNKQLRIMQHQSENLVLLTNSIQKDQTGENQKISSQPPVIIHTAATPMPTPRSSPYNELV 3111 K++ +V+ F RGI+ AIL+NTLSMG+EYH+QP +LT LE SNIVF+ +F +EM+LKL+ G LGYI+N +N+FDGI+V++ V E+ Q GLS+LRTFRLLR+LKLVRF+PALR+QL V++RT+DNVATF LL+LFIFIFSILGM LFGCKF ++ T DRKNFDSLLW+IVTVFQILTQEDWN VLYNGM TSSWAALYF+ALMTFGNYVLFNLLVAILVEGF +E DE K + + K LR +Q + L + G S PP+I HTAATPMPTP+SSP+ ++ Sbjct: 676 KLRRIVDSKYFNRGIMAAILVNTLSMGVEYHEQPDELTNALEISNIVFTSMFALEMLLKLLACGPLGYIRNPYNIFDGIVVIISVWEIVGQA-DGGLSVLRTFRLLRVLKLVRFLPALRRQLVVLMRTMDNVATFCMLLMLFIFIFSILGMHLFGCKFSLKTDSGDTVPDRKNFDSLLWAIVTVFQILTQEDWNVVLYNGMASTSSWAALYFVALMTFGNYVLFNLLVAILVEGFQAEGDATRSDTDEDKTSTHLEEDFDK-------LRDVQATEMKMYSLAVTPNGHLEGRG---SLPPPLITHTAATPMPTPKSSPHLDMA 988 HSP 4 Score: 112.849 bits (281), Expect = 3.586e-24 Identity = 73/278 (26.26%), Postives = 138/278 (49.64%), Query Frame = 1 Query: 3862 FRQKCQHIVDKKSFDYLVLFFITLNCITLAMERPSIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKFYYCDGPHLQAVKTKNDCLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFH 4695 F K + IVD K F+ ++ I +N +++ +E P L ++N +FT +F EM++K+L+ G L Y+++ +NI DG +V IS+ + ++G ++ +LR FRLLR L+ +R + P L+ + L+ ++ + ++ F IF ILG+ LF KF LK + + NFD+L A++ +F + +++ W ++Y G+ + + WA +YF++ + + + N+ V ++VE F Sbjct: 673 FSSKLRRIVDSKYFNRGIMAAILVNTLSMGVEYHEQPDELTNAL--EISNIVFTSMFALEMLLKLLACGPL----GYIRNPYNIFDGIVVIISVWE-----IVGQADGGLSVLRTFRLLRVLKLVRFL---PALRRQLVVLMRTMDNVATFCMLLMLFIFIFSILGMHLFGCKF----------------SLKTDSGDTVPDRKNFDSLLWAIVTVFQILTQEDWNVVLYNGMAST----------SSWAALYFVALMTFGNYVLFNLLVAILVEGFQ 910 HSP 5 Score: 82.0333 bits (201), Expect = 9.482e-15 Identity = 67/257 (26.07%), Postives = 126/257 (49.03%), Query Frame = 1 Query: 2101 PFNKNQNKTKRKNYLSICQQKIKTLVNDVKFQRGILIAILINTLSMGIEYHQQPVQLTQTLEFSNIVFSILFLIEMILKLIGEGILGYIKNGFNLFDGIIVVLGVIELCQQG---------GTSGLSILRTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKFCTIENNKRTCDR-KNFDSLLWSIVTVFQILTQEDWNTVLYNGM---TRTSSWAALYFIAL--MTFGNYVL 2826 P+ + + T+R + S+C L I I +N ++M +E++ QP L + L++ N VF+I+F+ E LKL+ G + K+ +N D IV+L ++ + + + + I+R R+ R+LKL++ +R L +++ + V L +L FI++ LG+ LFG C+ +N R F + + +T+F++ T ++WN ++ + + TR Y AL + F +VL Sbjct: 1497 PYYADYSHTRRSIH-SLCTSHYLDLF--------ITFIICLNVITMSMEHYNQPKSLDEALKYCNYVFTIVFVFEAALKLVAFGFRRFFKDRWNQLDLAIVLLSIMGIALEEIEMNAALPINPTIIRIMRVLRIARVLKLLKMATGMRALLDTVVQALPQVGNLGLLFMLLFFIYAALGVELFGRLECSEDNPCEGLSRHATFTNFGMAFLTLFRVSTGDNWNGIMKDTLRECTREDKHCLSYLPALSPVYFVTFVL 1744 HSP 6 Score: 75.485 bits (184), Expect = 8.063e-13 Identity = 71/224 (31.70%), Postives = 119/224 (53.12%), Query Frame = 1 Query: 4798 WENYS-KWRRTINSVVTSKYFDLAIAGVIGLNVITMATEFHMMPQVLKTALKVFNYFFTSTFVXXXXXXXXXXXXXRYISDKWNQLDMMIVILSIAGVVIDEVESNFMPINPTIMRVMRVLRIARVLKLLKMASGIRALLDTVIQALPQVGNXXXXXXXXXXXXXXXXVELFG-----RLECSDINPCVGLGRHAHFENFGMAFLTLFRIATGDNWNGIMKDTL 5451 W ++S K RR +V SKYF+ I I +N ++M E+H P L AL++ N FTS F LE LLKL+A G YI + +N D ++VI+S+ +V + + + V+R R+ RVLKL++ +R L +++ + V +L L +IF+ LG+ LFG + + D P +F++ A +T+F+I T ++WN ++ + + Sbjct: 670 WASFSSKLRR----IVDSKYFNRGIMAAILVNTLSMGVEYHEQPDELTNALEISNIVFTSMFALEMLLKLLACGPLGYIRNPYNIFDGIVVIISVWEIV-GQADGG--------LSVLRTFRLLRVLKLVRFLPALRRQLVVLMRTMDNVATFCMLLMLFIFIFSILGMHLFGCKFSLKTDSGDTVP-----DRKNFDSLLWAIVTVFQILTQEDWNVVLYNGM 875 HSP 7 Score: 75.0998 bits (183), Expect = 1.129e-12 Identity = 57/156 (36.54%), Postives = 88/156 (56.41%), Query Frame = 1 Query: 3916 LFFITLNCITLAMERP--SIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKG 4377 + I LNC+TL M RP + S+ L + F EM+IK+++ GL G + YL WN +D F+V +++ + GH+ + I R +R LRPLR I+R P ++++V LL +L +GN++L+C F IFGI+GVQL+ G Sbjct: 1 MLVIMLNCVTLGMFRPCEDVECRSERCSILEAFDDFIFAFFAVEMVIKMVALGLF-GQKCYLGDTWNRLDFFIVMAGMMEYSLD---GHNVSLSAI----RTVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAG 148 HSP 8 Score: 70.0922 bits (170), Expect = 3.770e-11 Identity = 66/286 (23.08%), Postives = 139/286 (48.60%), Query Frame = 1 Query: 2134 KNYLSICQQKIKTLVNDVKFQRGILIAILINTLSMGIEYHQQPVQLTQT--LEFSNIVFSILFLIEMILKLIGEGIL----GYIKNGFNLFDGIIVVLGVIELCQQGGTSGLSIL-------RTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKFCTIEN-------NKRTCD---------RKNFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTS----------SWAALYFIALMTFGNYVLFNLLVAILVEGFSSER 2874 +N L + QK+ + F +L+ I +N +++ +E T+ L SN +F+ +F++EM++K++ G+L Y+++ +N+ DG++V++ ++++ ++G + + R R LR L+++ P L+ + +I ++ + + F IF ILG+ LF KF E K C + NFD+L +++++F + +++ W ++Y+G+ W LYFI+ + ++ + N+ V ++VE F R Sbjct: 1185 QNRLRVSCQKV---IAHKMFDHVVLVFIFLNCITIALERPDIDPGSTERAFLSVSNYIFTAIFVVEMMVKVVALGLLWGEHAYLQSSWNVLDGLLVLVSLVDIIVAVASAGGAKILGVLRVLRLLRTLRPLRVISRAPGLKLVVETLISSLRPIGNIVLICCAFFIIFGILGVQLFKGKFYYCEGTDTRNITTKAECHAAHYRWVRRKYNFDNLGQALMSLFVLSSKDGWVNIMYDGLDAVGIDQQPVQNHNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHKCR 1467 HSP 9 Score: 63.929 bits (154), Expect = 2.639e-9 Identity = 33/118 (27.97%), Postives = 64/118 (54.24%), Query Frame = 1 Query: 334 VFHIFHQNKHPRDWCLKIITWPWFEQLSMTIIAVNCITLSMYQPCGDQNCETSKCQIMQAFDYIIFAFFTCEMVIKIIAMGFL-GDLGYFGDTWNRLDMFIVIVGSIEILPSTGNNIG 684 ++F R C K+I F+ + + I +NCIT+++ +P D + +++ + +YI A F EM++K++A+G L G+ Y +WN LD +V+V ++I+ + + G Sbjct: 1178 ALYLFPPQNRLRVSCQKVIAHKMFDHVVLVFIFLNCITIALERP--DIDPGSTERAFLSVSNYIFTAIFVVEMMVKVVALGLLWGEHAYLQSSWNVLDGLLVLVSLVDIIVAVASAGG 1293 HSP 10 Score: 55.4546 bits (132), Expect = 1.145e-6 Identity = 31/86 (36.05%), Postives = 50/86 (58.14%), Query Frame = 1 Query: 4462 NQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFH--KCQENQ 4713 N NFDN+G A +A+F + + +GWV IMY +DA H+ + IYFI +++ +FF++N+ + V+ F K +ENQ Sbjct: 250 NGAINFDNIGYAWIAIFQVITLEGWVDIMYYVMDA----------HSFYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQRENQ 325 HSP 11 Score: 54.299 bits (129), Expect = 2.610e-6 Identity = 26/80 (32.50%), Postives = 48/80 (60.00%), Query Frame = 1 Query: 1195 NFDNIGFAWVAIFQVISMESWVDIMYYVQDA----------HSFWDWIYFVALIIIGSFFMINLCLVVIASQFSETKRRE 1404 NFDN+G A +++F + S + WV+IMY DA H+ W +YF++ ++I SFF++N+ + V+ F + ++ + Sbjct: 1391 NFDNLGQALMSLFVLSSKDGWVNIMYDGLDAVGIDQQPVQNHNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHKCRQHQ 1470 HSP 12 Score: 52.373 bits (124), Expect = 9.693e-6 Identity = 23/78 (29.49%), Postives = 45/78 (57.69%), Query Frame = 1 Query: 2674 NFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTSSWAALYFIALMTFGNYVLFNLLVAILVEGFSSERLDEQKLLHNYR 2907 NFD++ ++ + +FQ++T E W ++Y M S + +YFI L+ G++ + NL + ++ FS + E +L+ R Sbjct: 254 NFDNIGYAWIAIFQVITLEGWVDIMYYVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQRENQLMREQR 331
BLAST of Voltage-dependent T-type calcium channel subunit alpha vs. Ensembl Mouse
Match: Cacna1g (calcium channel, voltage-dependent, T type, alpha 1G subunit [Source:MGI Symbol;Acc:MGI:1201678]) HSP 1 Score: 645.195 bits (1663), Expect = 0.000e+0 Identity = 388/612 (63.40%), Postives = 475/612 (77.61%), Query Frame = 1 Query: 3778 LSKCCPQPKGIFAKRYYHSLYVFSVDNQFRQKCQHIVDKKSFDYLVLFFITLNCITLAMERPSIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKFYYCDGPHLQAVKTKNDCLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFHKCQENQXXXXXXXXXXXXXXXXXXXXXHLRAPLYWENYSKWRRTINSVVTSKYFDLAIAGVIGLNVITMATEFHMMPQVLKTALKVFNYFFTSTFVXXXXXXXXXXXXXRYISDKWNQLDMMIVILSIAGVVIDEVESNF-MPINPTIMRVMRVLRIARVLKLLKMASGIRALLDTVIQALPQVGNXXXXXXXXXXXXXXXXVELFGRLECSDINPCVGLGRHAHFENFGMAFLTLFRIATGDNWNGIMKDTLREKCISSEDC-QRNCCVSAIIAPIYFVIFXXXXXXXXXXXXXXXXXKHLEESH 5607 L CC +R S Y+F ++FR C I+ K FD++VL I LNCIT+AMERP I PHS ER+FLT++NYIFT +F EM +KV++ G G+QAYL+S WN++DG LV IS++D+ ++++ +I G+LRV RLLRTLRPLRVISRA GLKLVV+TL+SSL+PIGNIV+ICC FFIIFGILGVQLFKGKF+ C G + + K+DC + S W KYNFDNLGQALM+LFVL+SKDGWV IMY G+DAVGV+ QP NHN W L+YFISFLL+VAFFVLNMFVGVVVENFHKC+++QE+EE RR KR +RLEKKR+ + Y+ +YS++R ++ + TS Y DL I GVIGLNV+TMA E + PQ+L ALK+ NY FT FVLE++ KLVA G R+ D+WNQLD+ IV+LSI G+ ++E+E N +PINPTI+R+MRVLRIARVLKLLKMA G+RALLDTV+QALPQVGNLGLLF LLF+IFAALGVELFG LEC + +PC GLGRHA F NFGMAFLTLFR++TGDNWNGIMKDTLR DC Q + C + +I+PIYFV FVL AQFVLVNVV+AVLMKHLEES+ Sbjct: 1245 LPACC-------RERDSWSAYIFPPQSRFRLLCHRIITHKMFDHVVLVIIFLNCITIAMERPKIDPHSAERIFLTLSNYIFTAVFLAEMTVKVVALGWCFGEQAYLRSSWNVLDGLLVLISVIDILVSMVSDSGTKILGMLRVLRLLRTLRPLRVISRAQGLKLVVETLMSSLKPIGNIVVICCAFFIIFGILGVQLFKGKFFVCQGEDTRNITNKSDCAEASY-RWVRHKYNFDNLGQALMSLFVLASKDGWVDIMYDGLDAVGVDQQPIMNHNPWMLLYFISFLLIVAFFVLNMFVGVVVENFHKCRQHQEEEEARRREEKRLKRLEKKRRKAQCKPYYSDYSRFRLLVHHLCTSHYLDLFITGVIGLNVVTMAMEHYQQPQILDEALKICNYIFTVIFVLESVFKLVAFGFRRFFQDRWNQLDLAIVLLSIMGITLEEIEVNASLPINPTIIRIMRVLRIARVLKLLKMAVGMRALLDTVMQALPQVGNLGLLFMLLFFIFAALGVELFGDLECDETHPCEGLGRHATFRNFGMAFLTLFRVSTGDNWNGIMKDTLR-------DCDQESTCYNTVISPIYFVSFVLTAQFVLVNVVIAVLMKHLEESN 1841 HSP 2 Score: 369.777 bits (948), Expect = 1.579e-102 Identity = 229/466 (49.14%), Postives = 307/466 (65.88%), Query Frame = 1 Query: 226 DFNLTDKSKADHCQQETDGTPINPNESLIYHGFYATVFHIFHQNKHPRDWCLKIITWPWFEQLSMTIIAVNCITLSMYQPCGDQNCETSKCQIMQAFDYIIFAFFTCEMVIKIIAMGFLGDLGYFGDTWNRLDMFIVIVGSIEILPSTGNNIGLTAIRTIRVLRPLRAINRIPSMRIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQMWQGVLRNRCYLNLNESFRHP-GLNLSSFYQINRTLFLNAVDKDFICSTDKNNGILKCSDIPPSIMLLSNNSLQICKQPARPFTDNLPTKHSCVNWNQYYTDCQPGEKNPYEGAINFDNIGFAWVAIFQVISMESWVDIMYYVQDAHSFWDWIYFVALIIIGSFFMINLCLVVIASQFSETKRRETERMWIERRRFNSSNCSSISKDEPQTCYLEXXXXXXXXXXXXYRRIVKLYNQIQIR----HSKTAQGNYQNK 1608 D + + ++ G+ + E L Y VF Q+ PR WCL+ + PWFE++SM +I +NC+TL M++PC D C++ +C+I+QAFD IFAFF EMV+K++A+G G Y GDTWNRLD FIVI G +E N+ +A+RT+RVLRPLRAINR+PSMRILV LLLDTLPMLGNVLLLCFFVFFIFGI+GVQ+W G+LRNRC+L E+F P ++L +YQ N + FICS + NG+ C +P A N + +CVNWNQYYT+C GE NP++GAINFDNIG+AW+AIFQVI++E WVDIMY+V DAHSF+++IYF+ LII+GSFFMINLCLVVIA+QFSETK+RE++ M +R RF S+ + S EP +CY E++K + I+ K RR+ ++ + +R S A+G + + Sbjct: 24 DLSGAGGRQGPGSTEKDPGSADSEAEGLPYPALAPVVFFYLSQDSRPRSWCLRTVCNPWFERVSMLVILLNCVTLGMFRPCEDIACDSQRCRILQAFDDFIFAFFAVEMVVKMVALGIFGKKCYLGDTWNRLDFFIVIAGMLEYSLDL-QNVSFSAVRTVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAGLLRNRCFLP--ENFSLPLSVDLEPYYQTE-----NEDESPFICSQPRENGMRSCRSVPTLRGEGGGGPPCGLDYEAY----NSSSNTTCVNWNQYYTNCSAGEHNPFKGAINFDNIGYAWIAIFQVITLEGWVDIMYFVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQRESQLMREQRVRFLSNASTLASFSEPGSCYEELLKYLVYILRKAARRLAQVSRAVGVRAGLLSSPVARGGQEPQ 477 HSP 3 Score: 338.191 bits (866), Expect = 7.322e-93 Identity = 219/478 (45.82%), Postives = 289/478 (60.46%), Query Frame = 1 Query: 1744 YPINFSNIPPKASPELSVIDVLNSPRHPNHLISDISSKSVSTETKRKSQYNSQILLEIPSTPANHSTTR--------DNYRWELTNNPLLTSKDKVYPQSVASRSSSINSCAY-------QIPRLTDSYSKHRRPFNKNQNKTKRKNYLSICQQKIKTLVNDVKFQRGILIAILINTLSMGIEYHQQPVQLTQTLEFSNIVFSILFLIEMILKLIGEGILGYIKNGFNLFDGIIVVLGVIELC-QQGGTSGLSILRTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKFCTIENNKRTCDRKNFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTSSWAALYFIALMTFGNYVLFNLLVAILVEGFSSERLDEQKLLHNYRQSLKKRRANNKQLRIMQHQSENLVLLTNSIQKD----------QTGENQKI--SSQPPVIIHTAATPMPTPRSS 3093 YP ++ PP+ + ++++V SP P +I S+ K LLE ST A HS+ + D+ + P P+S +S A Q L D + + R + + + + + +V+ F RGI+IAIL+NTLSMGIEYH+QP +LT LE SNIVF+ LF +EM+LKL+ G GYIKN +N+FDG+IVV+ V E+ QQGG GLS+LRTFRL+R+LKLVRF+PAL++QL V+++T+DNVATF LL+LFIFIFSILGM LFGCKF + + DRKNFDSLLW+IVTVFQILTQEDWN VLYNGM TSSWAALYFIALMTFGNYVLFNLLVAILVEGF +E + +++ + S + N++ + +SE + S+ D GE+ ++ S PP+IIHTAATPM P+SS Sbjct: 590 YPTVHTSPPPEMLKDKALVEVAPSPGPPTLTSFNIPPGPFSSMHK---------LLETQSTGACHSSCKISSPCSKADSGACGPDSCPYCARTGAGEPESADHEMPDSDSEAVYEFTQDAQHSDLRDPHRRRRPSLGPDAEPSSVLAFWRLICDTFRKIVDSKYFGRGIMIAILVNTLSMGIEYHEQPEELTNALEISNIVFTSLFALEMLLKLLVYGPFGYIKNPYNIFDGVIVVISVWEIVGQQGG--GLSVLRTFRLMRVLKLVRFLPALQRQLVVLMKTMDNVATFCMLLMLFIFIFSILGMHLFGCKFASERDGDTLPDRKNFDSLLWAIVTVFQILTQEDWNKVLYNGMASTSSWAALYFIALMTFGNYVLFNLLVAILVEGFQAEEIGKREDTSG-QLSCIQLPVNSQGGDATKSESEP-DFFSPSVDGDGDRKKRLALVALGEHSELRKSLLPPLIIHTAATPMSLPKSS 1054 HSP 4 Score: 108.997 bits (271), Expect = 6.915e-23 Identity = 74/275 (26.91%), Postives = 136/275 (49.45%), Query Frame = 1 Query: 3877 QHIVDKKSFDYLVLFFITLNCITLAMERPSIPPHSKERL--FLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKFYYCDGPHLQAVKTKNDCLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFH 4695 + IVD K F ++ I +N +++ +E P E L L ++N +FT +F EM++K+L + G Y+K+ +NI DG +V IS+ + ++G +LR FRL+R L+ +R + P L+ + L+ ++ + ++ F IF ILG+ LF KF A + D L + NFD+L A++ +F + +++ W +++Y G+ + + WA +YFI+ + + + N+ V ++VE F Sbjct: 737 RKIVDSKYFGRGIMIAILVNTLSMGIEYHEQP----EELTNALEISNIVFTSLFALEMLLKLL----VYGPFGYIKNPYNIFDGVIVVISVWE-----IVGQQGGGLSVLRTFRLMRVLKLVRFL---PALQRQLVVLMKTMDNVATFCMLLMLFIFIFSILGMHLFGCKF---------ASERDGDTLP--------DRKNFDSLLWAIVTVFQILTQEDWNKVLYNGMAST----------SSWAALYFIALMTFGNYVLFNLLVAILVEGFQ 968 HSP 5 Score: 83.5741 bits (205), Expect = 3.738e-15 Identity = 58/235 (24.68%), Postives = 123/235 (52.34%), Query Frame = 1 Query: 2215 ILINTLSMGIEYHQQPVQLTQTLEFSNIVFSILFLIEMILKLIGEGILGYIKNGFNLFDGIIVVLGVIELCQQG---------GTSGLSILRTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKFC----TIENNKRTCDRKNFDSLLWSIVTVFQILTQEDWNTVLYNGM--------TRTSSWAALYFIALMTFGNYVLFNLLVAILVE 2856 I +N ++M +E++QQP L + L+ N +F+++F++E + KL+ G + ++ +N D IV+L ++ + + + + I+R R+ R+LKL++ +R L +++ + V L +L FIF+ LG+ LFG C E R +NF + +T+F++ T ++WN ++ + + + + +YF++ + +VL N+++A+L++ Sbjct: 1604 IGLNVVTMAMEHYQQPQILDEALKICNYIFTVIFVLESVFKLVAFGFRRFFQDRWNQLDLAIVLLSIMGITLEEIEVNASLPINPTIIRIMRVLRIARVLKLLKMAVGMRALLDTVMQALPQVGNLGLLFMLLFFIFAALGVELFGDLECDETHPCEGLGRHATFRNFG---MAFLTLFRVSTGDNWNGIMKDTLRDCDQESTCYNTVISPIYFVSFVLTAQFVLVNVVIAVLMK 1835 HSP 6 Score: 80.4925 bits (197), Expect = 2.958e-14 Identity = 70/215 (32.56%), Postives = 108/215 (50.23%), Query Frame = 1 Query: 3739 EDPDEEDMEAMICLSKCCPQPKGIFAKRYYHSLYVFSVDNQFRQKCQHIVDKKSFDYLVLFFITLNCITLAMERP--SIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKG 4377 +DP D EA + P P +Y S D++ R C V F+ + + I LNC+TL M RP I S+ L + F EM++K+++ G+ G + YL WN +D F+V +L+ + + N F +R +R LRPLR I+R P ++++V LL +L +GN++L+C F IFGI+GVQL+ G Sbjct: 39 KDPGSADSEA-----EGLPYPALAPVVFFY-----LSQDSRPRSWCLRTVCNPWFERVSMLVILLNCVTLGMFRPCEDIACDSQRCRILQAFDDFIFAFFAVEMVVKMVALGIF-GKKCYLGDTWNRLDFFIVIAGMLEYSLDL----QNVSFSAVRT---VRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAG 235 HSP 7 Score: 72.0182 bits (175), Expect = 1.128e-11 Identity = 67/215 (31.16%), Postives = 113/215 (52.56%), Query Frame = 1 Query: 4816 WR---RTINSVVTSKYFDLAIAGVIGLNVITMATEFHMMPQVLKTALKVFNYFFTSTFVXXXXXXXXXXXXXRYISDKWNQLDMMIVILSIAGVVIDEVESNFMPINPTIMRVMRVLRIARVLKLLKMASGIRALLDTVIQALPQVGNXXXXXXXXXXXXXXXXVELFGRLECSDINPCVGLGRHAHFENFGMAFLTLFRIATGDNWNGIMKDTL 5451 WR T +V SKYF I I +N ++M E+H P+ L AL++ N FTS F LE LLKL+ G YI + +N D +IV++S+ +V + + V+R R+ RVLKL++ ++ L +++ + V +L L +IF+ LG+ LFG S+ + L +F++ A +T+F+I T ++WN ++ + + Sbjct: 729 WRLICDTFRKIVDSKYFGRGIMIAILVNTLSMGIEYHEQPEELTNALEISNIVFTSLFALEMLLKLLVYGPFGYIKNPYNIFDGVIVVISVWEIVGQQGGG---------LSVLRTFRLMRVLKLVRFLPALQRQLVVLMKTMDNVATFCMLLMLFIFIFSILGMHLFGCKFASERDGDT-LPDRKNFDSLLWAIVTVFQILTQEDWNKVLYNGM 933 HSP 8 Score: 66.2402 bits (160), Expect = 6.596e-10 Identity = 38/116 (32.76%), Postives = 66/116 (56.90%), Query Frame = 1 Query: 340 HIFHQNKHPRDWCLKIITWPWFEQLSMTIIAVNCITLSMYQPCGDQNCETSKCQIMQAFDYIIFAFFTCEMVIKIIAMGF-LGDLGYFGDTWNRLDMFIVIVGSIEILPSTGNNIG 684 +IF R C +IIT F+ + + II +NCIT++M +P D + +++ + +YI A F EM +K++A+G+ G+ Y +WN LD +V++ I+IL S ++ G Sbjct: 1258 YIFPPQSRFRLLCHRIITHKMFDHVVLVIIFLNCITIAMERPKIDPH--SAERIFLTLSNYIFTAVFLAEMTVKVVALGWCFGEQAYLRSSWNVLDGLLVLISVIDILVSMVSDSG 1371 HSP 9 Score: 64.3142 bits (155), Expect = 2.158e-9 Identity = 63/270 (23.33%), Postives = 123/270 (45.56%), Query Frame = 1 Query: 2191 FQRGILIAILINTLSMGIEYHQQPVQLTQT--LEFSNIVFSILFLIEMILKLIGEGIL----GYIKNGFNLFDGIIVVLGVIE-LCQQGGTSGLSILRTFRLLR---------ILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKF--CTIEN-----NKRTC---------DRKNFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTS----------SWAALYFIALMTFGNYVLFNLLVAILVEGFSSER 2874 F +L+ I +N +++ +E + + L SN +F+ +FL EM +K++ G Y+++ +N+ DG++V++ VI+ L SG IL R+LR ++ + + + + L ++ I N+ + I G+ LF KF C E+ NK C + NFD+L +++++F + +++ W ++Y+G+ W LYFI+ + + + N+ V ++VE F R Sbjct: 1279 FDHVVLVIIFLNCITIAMERPKIDPHSAERIFLTLSNYIFTAVFLAEMTVKVVALGWCFGEQAYLRSSWNVLDGLLVLISVIDILVSMVSDSGTKILGMLRVLRLLRTLRPLRVISRAQGLKLVVETLMSSLKPIGNIVVICCAFFIIFGIL---GVQLFKGKFFVCQGEDTRNITNKSDCAEASYRWVRHKYNFDNLGQALMSLFVLASKDGWVDIMYDGLDAVGVDQQPIMNHNPWMLLYFISFLLIVAFFVLNMFVGVVVENFHKCR 1545 HSP 10 Score: 56.6102 bits (135), Expect = 4.374e-7 Identity = 28/95 (29.47%), Postives = 51/95 (53.68%), Query Frame = 1 Query: 1150 TDCQPGEKNPYEGAINFDNIGFAWVAIFQVISMESWVDIMYYVQDA----------HSFWDWIYFVALIIIGSFFMINLCLVVIASQFSETKRRE 1404 +DC NFDN+G A +++F + S + WVDIMY DA H+ W +YF++ ++I +FF++N+ + V+ F + ++ + Sbjct: 1454 SDCAEASYRWVRHKYNFDNLGQALMSLFVLASKDGWVDIMYDGLDAVGVDQQPIMNHNPWMLLYFISFLLIVAFFVLNMFVGVVVENFHKCRQHQ 1548 HSP 11 Score: 55.4546 bits (132), Expect = 1.219e-6 Identity = 29/96 (30.21%), Postives = 53/96 (55.21%), Query Frame = 1 Query: 4426 NDCLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFHKCQENQ 4713 +C N +K NFDN+G A +A+F + + +GWV IMY +DA H+ + IYFI +++ +FF++N+ + V+ F + ++ + Sbjct: 321 TNCSAGEHNPFKG-AINFDNIGYAWIAIFQVITLEGWVDIMYFVMDA----------HSFYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQRE 405 HSP 12 Score: 53.9138 bits (128), Expect = 3.179e-6 Identity = 23/72 (31.94%), Postives = 43/72 (59.72%), Query Frame = 1 Query: 1195 NFDNIGFAWVAIFQVISMESWVDIMYYVQDAHSFWDWIYFVALIIIGSFFMINLCLVVIASQF--SETKRRE 1404 NFD++ +A V +FQ+++ E W ++Y + S W +YF+AL+ G++ + NL + ++ F E +RE Sbjct: 905 NFDSLLWAIVTVFQILTQEDWNKVLYNGMASTSSWAALYFIALMTFGNYVLFNLLVAILVEGFQAEEIGKRE 976 HSP 13 Score: 52.373 bits (124), Expect = 8.714e-6 Identity = 23/78 (29.49%), Postives = 45/78 (57.69%), Query Frame = 1 Query: 2674 NFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTSSWAALYFIALMTFGNYVLFNLLVAILVEGFSSERLDEQKLLHNYR 2907 NFD++ ++ + +FQ++T E W ++Y M S + +YFI L+ G++ + NL + ++ FS + E +L+ R Sbjct: 336 NFDNIGYAWIAIFQVITLEGWVDIMYFVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQRESQLMREQR 413
BLAST of Voltage-dependent T-type calcium channel subunit alpha vs. Ensembl Mouse
Match: Cacna1g (calcium channel, voltage-dependent, T type, alpha 1G subunit [Source:MGI Symbol;Acc:MGI:1201678]) HSP 1 Score: 644.81 bits (1662), Expect = 0.000e+0 Identity = 388/612 (63.40%), Postives = 475/612 (77.61%), Query Frame = 1 Query: 3778 LSKCCPQPKGIFAKRYYHSLYVFSVDNQFRQKCQHIVDKKSFDYLVLFFITLNCITLAMERPSIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKFYYCDGPHLQAVKTKNDCLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFHKCQENQXXXXXXXXXXXXXXXXXXXXXHLRAPLYWENYSKWRRTINSVVTSKYFDLAIAGVIGLNVITMATEFHMMPQVLKTALKVFNYFFTSTFVXXXXXXXXXXXXXRYISDKWNQLDMMIVILSIAGVVIDEVESNF-MPINPTIMRVMRVLRIARVLKLLKMASGIRALLDTVIQALPQVGNXXXXXXXXXXXXXXXXVELFGRLECSDINPCVGLGRHAHFENFGMAFLTLFRIATGDNWNGIMKDTLREKCISSEDC-QRNCCVSAIIAPIYFVIFXXXXXXXXXXXXXXXXXKHLEESH 5607 L CC +R S Y+F ++FR C I+ K FD++VL I LNCIT+AMERP I PHS ER+FLT++NYIFT +F EM +KV++ G G+QAYL+S WN++DG LV IS++D+ ++++ +I G+LRV RLLRTLRPLRVISRA GLKLVV+TL+SSL+PIGNIV+ICC FFIIFGILGVQLFKGKF+ C G + + K+DC + S W KYNFDNLGQALM+LFVL+SKDGWV IMY G+DAVGV+ QP NHN W L+YFISFLL+VAFFVLNMFVGVVVENFHKC+++QE+EE RR KR +RLEKKR+ + Y+ +YS++R ++ + TS Y DL I GVIGLNV+TMA E + PQ+L ALK+ NY FT FVLE++ KLVA G R+ D+WNQLD+ IV+LSI G+ ++E+E N +PINPTI+R+MRVLRIARVLKLLKMA G+RALLDTV+QALPQVGNLGLLF LLF+IFAALGVELFG LEC + +PC GLGRHA F NFGMAFLTLFR++TGDNWNGIMKDTLR DC Q + C + +I+PIYFV FVL AQFVLVNVV+AVLMKHLEES+ Sbjct: 1222 LPACC-------RERDSWSAYIFPPQSRFRLLCHRIITHKMFDHVVLVIIFLNCITIAMERPKIDPHSAERIFLTLSNYIFTAVFLAEMTVKVVALGWCFGEQAYLRSSWNVLDGLLVLISVIDILVSMVSDSGTKILGMLRVLRLLRTLRPLRVISRAQGLKLVVETLMSSLKPIGNIVVICCAFFIIFGILGVQLFKGKFFVCQGEDTRNITNKSDCAEASY-RWVRHKYNFDNLGQALMSLFVLASKDGWVDIMYDGLDAVGVDQQPIMNHNPWMLLYFISFLLIVAFFVLNMFVGVVVENFHKCRQHQEEEEARRREEKRLKRLEKKRRKAQCKPYYSDYSRFRLLVHHLCTSHYLDLFITGVIGLNVVTMAMEHYQQPQILDEALKICNYIFTVIFVLESVFKLVAFGFRRFFQDRWNQLDLAIVLLSIMGITLEEIEVNASLPINPTIIRIMRVLRIARVLKLLKMAVGMRALLDTVMQALPQVGNLGLLFMLLFFIFAALGVELFGDLECDETHPCEGLGRHATFRNFGMAFLTLFRVSTGDNWNGIMKDTLR-------DCDQESTCYNTVISPIYFVSFVLTAQFVLVNVVIAVLMKHLEESN 1818 HSP 2 Score: 369.392 bits (947), Expect = 1.838e-102 Identity = 229/466 (49.14%), Postives = 307/466 (65.88%), Query Frame = 1 Query: 226 DFNLTDKSKADHCQQETDGTPINPNESLIYHGFYATVFHIFHQNKHPRDWCLKIITWPWFEQLSMTIIAVNCITLSMYQPCGDQNCETSKCQIMQAFDYIIFAFFTCEMVIKIIAMGFLGDLGYFGDTWNRLDMFIVIVGSIEILPSTGNNIGLTAIRTIRVLRPLRAINRIPSMRIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQMWQGVLRNRCYLNLNESFRHP-GLNLSSFYQINRTLFLNAVDKDFICSTDKNNGILKCSDIPPSIMLLSNNSLQICKQPARPFTDNLPTKHSCVNWNQYYTDCQPGEKNPYEGAINFDNIGFAWVAIFQVISMESWVDIMYYVQDAHSFWDWIYFVALIIIGSFFMINLCLVVIASQFSETKRRETERMWIERRRFNSSNCSSISKDEPQTCYLEXXXXXXXXXXXXYRRIVKLYNQIQIR----HSKTAQGNYQNK 1608 D + + ++ G+ + E L Y VF Q+ PR WCL+ + PWFE++SM +I +NC+TL M++PC D C++ +C+I+QAFD IFAFF EMV+K++A+G G Y GDTWNRLD FIVI G +E N+ +A+RT+RVLRPLRAINR+PSMRILV LLLDTLPMLGNVLLLCFFVFFIFGI+GVQ+W G+LRNRC+L E+F P ++L +YQ N + FICS + NG+ C +P A N + +CVNWNQYYT+C GE NP++GAINFDNIG+AW+AIFQVI++E WVDIMY+V DAHSF+++IYF+ LII+GSFFMINLCLVVIA+QFSETK+RE++ M +R RF S+ + S EP +CY E++K + I+ K RR+ ++ + +R S A+G + + Sbjct: 24 DLSGAGGRQGPGSTEKDPGSADSEAEGLPYPALAPVVFFYLSQDSRPRSWCLRTVCNPWFERVSMLVILLNCVTLGMFRPCEDIACDSQRCRILQAFDDFIFAFFAVEMVVKMVALGIFGKKCYLGDTWNRLDFFIVIAGMLEYSLDL-QNVSFSAVRTVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAGLLRNRCFLP--ENFSLPLSVDLEPYYQTE-----NEDESPFICSQPRENGMRSCRSVPTLRGEGGGGPPCGLDYEAY----NSSSNTTCVNWNQYYTNCSAGEHNPFKGAINFDNIGYAWIAIFQVITLEGWVDIMYFVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQRESQLMREQRVRFLSNASTLASFSEPGSCYEELLKYLVYILRKAARRLAQVSRAVGVRAGLLSSPVARGGQEPQ 477 HSP 3 Score: 334.339 bits (856), Expect = 1.206e-91 Identity = 216/470 (45.96%), Postives = 280/470 (59.57%), Query Frame = 1 Query: 1744 YPINFSNIPPKASPELSVIDVLNSPRHPNHLISDISSKSVSTETKRKSQYNSQILLEIPSTPANHSTTR--------DNYRWELTNNPLLTSKDKVYPQSVASRSSSINSCAY-------QIPRLTDSYSKHRRPFNKNQNKTKRKNYLSICQQKIKTLVNDVKFQRGILIAILINTLSMGIEYHQQPVQLTQTLEFSNIVFSILFLIEMILKLIGEGILGYIKNGFNLFDGIIVVLGVIELC-QQGGTSGLSILRTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKFCTIENNKRTCDRKNFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTSSWAALYFIALMTFGNYVLFNLLVAILVEGFSSE--RLDEQKLLHNYRQSLKKRRANNKQLRIMQHQSENLVLLTNSIQKDQTGENQKI--SSQPPVIIHTAATPMPTPRSS 3093 YP ++ PP+ + ++++V SP P +I S+ K LLE ST A HS+ + D+ + P P+S +S A Q L D + + R + + + + + +V+ F RGI+IAIL+NTLSMGIEYH+QP +LT LE SNIVF+ LF +EM+LKL+ G GYIKN +N+FDG+IVV+ V E+ QQGG GLS+LRTFRL+R+LKLVRF+PAL++QL V+++T+DNVATF LL+LFIFIFSILGM LFGCKF + + DRKNFDSLLW+IVTVFQILTQEDWN VLYNGM TSSWAALYFIALMTFGNYVLFNLLVAILVEGF +E + + S+ K+L ++ GE+ ++ S PP+IIHTAATPM P+SS Sbjct: 590 YPTVHTSPPPEMLKDKALVEVAPSPGPPTLTSFNIPPGPFSSMHK---------LLETQSTGACHSSCKISSPCSKADSGACGPDSCPYCARTGAGEPESADHEMPDSDSEAVYEFTQDAQHSDLRDPHRRRRPSLGPDAEPSSVLAFWRLICDTFRKIVDSKYFGRGIMIAILVNTLSMGIEYHEQPEELTNALEISNIVFTSLFALEMLLKLLVYGPFGYIKNPYNIFDGVIVVISVWEIVGQQGG--GLSVLRTFRLMRVLKLVRFLPALQRQLVVLMKTMDNVATFCMLLMLFIFIFSILGMHLFGCKFASERDGDTLPDRKNFDSLLWAIVTVFQILTQEDWNKVLYNGMASTSSWAALYFIALMTFGNYVLFNLLVAILVEGFQAEGDATKSESEPDFFSPSVDGDGDRKKRLALV-----------------ALGEHSELRKSLLPPLIIHTAATPMSLPKSS 1031 HSP 4 Score: 108.612 bits (270), Expect = 8.160e-23 Identity = 74/275 (26.91%), Postives = 136/275 (49.45%), Query Frame = 1 Query: 3877 QHIVDKKSFDYLVLFFITLNCITLAMERPSIPPHSKERL--FLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKFYYCDGPHLQAVKTKNDCLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFH 4695 + IVD K F ++ I +N +++ +E P E L L ++N +FT +F EM++K+L + G Y+K+ +NI DG +V IS+ + ++G +LR FRL+R L+ +R + P L+ + L+ ++ + ++ F IF ILG+ LF KF A + D L + NFD+L A++ +F + +++ W +++Y G+ + + WA +YFI+ + + + N+ V ++VE F Sbjct: 737 RKIVDSKYFGRGIMIAILVNTLSMGIEYHEQP----EELTNALEISNIVFTSLFALEMLLKLL----VYGPFGYIKNPYNIFDGVIVVISVWE-----IVGQQGGGLSVLRTFRLMRVLKLVRFL---PALQRQLVVLMKTMDNVATFCMLLMLFIFIFSILGMHLFGCKF---------ASERDGDTLP--------DRKNFDSLLWAIVTVFQILTQEDWNKVLYNGMAST----------SSWAALYFIALMTFGNYVLFNLLVAILVEGFQ 968 HSP 5 Score: 83.1889 bits (204), Expect = 4.232e-15 Identity = 58/235 (24.68%), Postives = 123/235 (52.34%), Query Frame = 1 Query: 2215 ILINTLSMGIEYHQQPVQLTQTLEFSNIVFSILFLIEMILKLIGEGILGYIKNGFNLFDGIIVVLGVIELCQQG---------GTSGLSILRTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKFC----TIENNKRTCDRKNFDSLLWSIVTVFQILTQEDWNTVLYNGM--------TRTSSWAALYFIALMTFGNYVLFNLLVAILVE 2856 I +N ++M +E++QQP L + L+ N +F+++F++E + KL+ G + ++ +N D IV+L ++ + + + + I+R R+ R+LKL++ +R L +++ + V L +L FIF+ LG+ LFG C E R +NF + +T+F++ T ++WN ++ + + + + +YF++ + +VL N+++A+L++ Sbjct: 1581 IGLNVVTMAMEHYQQPQILDEALKICNYIFTVIFVLESVFKLVAFGFRRFFQDRWNQLDLAIVLLSIMGITLEEIEVNASLPINPTIIRIMRVLRIARVLKLLKMAVGMRALLDTVMQALPQVGNLGLLFMLLFFIFAALGVELFGDLECDETHPCEGLGRHATFRNFG---MAFLTLFRVSTGDNWNGIMKDTLRDCDQESTCYNTVISPIYFVSFVLTAQFVLVNVVIAVLMK 1812 HSP 6 Score: 80.4925 bits (197), Expect = 2.831e-14 Identity = 70/215 (32.56%), Postives = 108/215 (50.23%), Query Frame = 1 Query: 3739 EDPDEEDMEAMICLSKCCPQPKGIFAKRYYHSLYVFSVDNQFRQKCQHIVDKKSFDYLVLFFITLNCITLAMERP--SIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKG 4377 +DP D EA + P P +Y S D++ R C V F+ + + I LNC+TL M RP I S+ L + F EM++K+++ G+ G + YL WN +D F+V +L+ + + N F +R +R LRPLR I+R P ++++V LL +L +GN++L+C F IFGI+GVQL+ G Sbjct: 39 KDPGSADSEA-----EGLPYPALAPVVFFY-----LSQDSRPRSWCLRTVCNPWFERVSMLVILLNCVTLGMFRPCEDIACDSQRCRILQAFDDFIFAFFAVEMVVKMVALGIF-GKKCYLGDTWNRLDFFIVIAGMLEYSLDL----QNVSFSAVRT---VRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAG 235 HSP 7 Score: 72.0182 bits (175), Expect = 1.145e-11 Identity = 67/215 (31.16%), Postives = 113/215 (52.56%), Query Frame = 1 Query: 4816 WR---RTINSVVTSKYFDLAIAGVIGLNVITMATEFHMMPQVLKTALKVFNYFFTSTFVXXXXXXXXXXXXXRYISDKWNQLDMMIVILSIAGVVIDEVESNFMPINPTIMRVMRVLRIARVLKLLKMASGIRALLDTVIQALPQVGNXXXXXXXXXXXXXXXXVELFGRLECSDINPCVGLGRHAHFENFGMAFLTLFRIATGDNWNGIMKDTL 5451 WR T +V SKYF I I +N ++M E+H P+ L AL++ N FTS F LE LLKL+ G YI + +N D +IV++S+ +V + + V+R R+ RVLKL++ ++ L +++ + V +L L +IF+ LG+ LFG S+ + L +F++ A +T+F+I T ++WN ++ + + Sbjct: 729 WRLICDTFRKIVDSKYFGRGIMIAILVNTLSMGIEYHEQPEELTNALEISNIVFTSLFALEMLLKLLVYGPFGYIKNPYNIFDGVIVVISVWEIVGQQGGG---------LSVLRTFRLMRVLKLVRFLPALQRQLVVLMKTMDNVATFCMLLMLFIFIFSILGMHLFGCKFASERDGDT-LPDRKNFDSLLWAIVTVFQILTQEDWNKVLYNGM 933 HSP 8 Score: 66.2402 bits (160), Expect = 6.532e-10 Identity = 38/116 (32.76%), Postives = 66/116 (56.90%), Query Frame = 1 Query: 340 HIFHQNKHPRDWCLKIITWPWFEQLSMTIIAVNCITLSMYQPCGDQNCETSKCQIMQAFDYIIFAFFTCEMVIKIIAMGF-LGDLGYFGDTWNRLDMFIVIVGSIEILPSTGNNIG 684 +IF R C +IIT F+ + + II +NCIT++M +P D + +++ + +YI A F EM +K++A+G+ G+ Y +WN LD +V++ I+IL S ++ G Sbjct: 1235 YIFPPQSRFRLLCHRIITHKMFDHVVLVIIFLNCITIAMERPKIDPH--SAERIFLTLSNYIFTAVFLAEMTVKVVALGWCFGEQAYLRSSWNVLDGLLVLISVIDILVSMVSDSG 1348 HSP 9 Score: 64.3142 bits (155), Expect = 2.229e-9 Identity = 63/270 (23.33%), Postives = 123/270 (45.56%), Query Frame = 1 Query: 2191 FQRGILIAILINTLSMGIEYHQQPVQLTQT--LEFSNIVFSILFLIEMILKLIGEGIL----GYIKNGFNLFDGIIVVLGVIE-LCQQGGTSGLSILRTFRLLR---------ILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKF--CTIEN-----NKRTC---------DRKNFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTS----------SWAALYFIALMTFGNYVLFNLLVAILVEGFSSER 2874 F +L+ I +N +++ +E + + L SN +F+ +FL EM +K++ G Y+++ +N+ DG++V++ VI+ L SG IL R+LR ++ + + + + L ++ I N+ + I G+ LF KF C E+ NK C + NFD+L +++++F + +++ W ++Y+G+ W LYFI+ + + + N+ V ++VE F R Sbjct: 1256 FDHVVLVIIFLNCITIAMERPKIDPHSAERIFLTLSNYIFTAVFLAEMTVKVVALGWCFGEQAYLRSSWNVLDGLLVLISVIDILVSMVSDSGTKILGMLRVLRLLRTLRPLRVISRAQGLKLVVETLMSSLKPIGNIVVICCAFFIIFGIL---GVQLFKGKFFVCQGEDTRNITNKSDCAEASYRWVRHKYNFDNLGQALMSLFVLASKDGWVDIMYDGLDAVGVDQQPIMNHNPWMLLYFISFLLIVAFFVLNMFVGVVVENFHKCR 1522 HSP 10 Score: 56.6102 bits (135), Expect = 4.443e-7 Identity = 28/95 (29.47%), Postives = 51/95 (53.68%), Query Frame = 1 Query: 1150 TDCQPGEKNPYEGAINFDNIGFAWVAIFQVISMESWVDIMYYVQDA----------HSFWDWIYFVALIIIGSFFMINLCLVVIASQFSETKRRE 1404 +DC NFDN+G A +++F + S + WVDIMY DA H+ W +YF++ ++I +FF++N+ + V+ F + ++ + Sbjct: 1431 SDCAEASYRWVRHKYNFDNLGQALMSLFVLASKDGWVDIMYDGLDAVGVDQQPIMNHNPWMLLYFISFLLIVAFFVLNMFVGVVVENFHKCRQHQ 1525 HSP 11 Score: 55.4546 bits (132), Expect = 1.208e-6 Identity = 29/96 (30.21%), Postives = 53/96 (55.21%), Query Frame = 1 Query: 4426 NDCLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFHKCQENQ 4713 +C N +K NFDN+G A +A+F + + +GWV IMY +DA H+ + IYFI +++ +FF++N+ + V+ F + ++ + Sbjct: 321 TNCSAGEHNPFKG-AINFDNIGYAWIAIFQVITLEGWVDIMYFVMDA----------HSFYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQRE 405 HSP 12 Score: 52.7582 bits (125), Expect = 6.880e-6 Identity = 22/75 (29.33%), Postives = 44/75 (58.67%), Query Frame = 1 Query: 1195 NFDNIGFAWVAIFQVISMESWVDIMYYVQDAHSFWDWIYFVALIIIGSFFMINLCLVVIASQF---SETKRRETE 1410 NFD++ +A V +FQ+++ E W ++Y + S W +YF+AL+ G++ + NL + ++ F + + E+E Sbjct: 905 NFDSLLWAIVTVFQILTQEDWNKVLYNGMASTSSWAALYFIALMTFGNYVLFNLLVAILVEGFQAEGDATKSESE 979 HSP 13 Score: 52.373 bits (124), Expect = 9.468e-6 Identity = 23/78 (29.49%), Postives = 45/78 (57.69%), Query Frame = 1 Query: 2674 NFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTSSWAALYFIALMTFGNYVLFNLLVAILVEGFSSERLDEQKLLHNYR 2907 NFD++ ++ + +FQ++T E W ++Y M S + +YFI L+ G++ + NL + ++ FS + E +L+ R Sbjct: 336 NFDNIGYAWIAIFQVITLEGWVDIMYFVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQRESQLMREQR 413
BLAST of Voltage-dependent T-type calcium channel subunit alpha vs. UniProt/SwissProt
Match: sp|O95180|CAC1H_HUMAN (Voltage-dependent T-type calcium channel subunit alpha-1H OS=Homo sapiens OX=9606 GN=CACNA1H PE=1 SV=4) HSP 1 Score: 654.055 bits (1686), Expect = 0.000e+0 Identity = 413/683 (60.47%), Postives = 508/683 (74.38%), Query Frame = 1 Query: 3667 REKALEEPDDSNSESQNSSRMNNVEDPDEEDMEAMICLSKCCPQPKGIFAKRYYHSLYVFSVDNQFRQKCQHIVDKKSFDYLVLFFITLNCITLAMERPSIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKFYYCDGPHLQAVKTKNDCLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFHKCQENQXXXXXXXXXXXXXXXXXXXXXHL-------RAPLYWENYSKWRRTINSVVTSKYFDLAIAGVIGLNVITMATEFHMMPQVLKTALKVFNYFFTSTFVXXXXXXXXXXXXXRYISDKWNQLDMMIVILSIAGVVIDEVE-SNFMPINPTIMRVMRVLRIARVLKLLKMASGIRALLDTVIQALPQVGNXXXXXXXXXXXXXXXXVELFGRLECSDINPCVGLGRHAHFENFGMAFLTLFRIATGDNWNGIMKDTLREKCISSEDCQRNCCVSAIIA--PIYFVIFXXXXXXXXXXXXXXXXXKHLEESHKMMCDDYELEREVQRDLDEEAKELAR 5685 RE A E DDS E R++ V +P + C S R +LY+FS N+FR CQ ++ K FD++VL FI LNC+T+A+ERP I P S ER+FL+V+NYIFT IF EM++KV++ GLL G+ AYL+S WN++DG LV +SL+D+ + + +I G+LRV RLLRTLRPLRVISRAPGLKLVV+TL+SSLRPIGNIVLICC FFIIFGILGVQLFKGKFYYC+GP + + TK C + + W +KYNFDNLGQALM+LFVLSSKDGWV IMY G+DAVGV+ QP +NHN W L+YFISFLL+V+FFVLNMFVGVVVENFHKC+++QE EE RR KR RRLE++R+ R P Y+ +YS RR+I+S+ TS Y DL I +I +NVITM+ E + P+ L ALK NY FT FV EA LKLVA G R+ D+WNQLD+ IV+LS+ G+ ++E+E S +PINPTI+R+MRVLRIARVLKLLKMA+G+RALLDTV+QALPQVGNLGLLF LLF+I+AALGVELFGRLECS+ NPC GL RHA F NFGMAFLTLFR++TGDNWNGIMKDTLRE S ED C+S + A P+YFV FVL+AQFVLVNVVVAVLMKHLEES+K +D EL+ E++ ++ + R Sbjct: 1236 REDAAELDDDS--EDSCCLRLHKVLEP----YKPQWCRS------------REAWALYLFSPQNRFRVSCQKVITHKMFDHVVLVFIFLNCVTIALERPDIDPGSTERVFLSVSNYIFTAIFVAEMMVKVVALGLLSGEHAYLQSSWNLLDGLLVLVSLVDIVVAMASAGGAKILGVLRVLRLLRTLRPLRVISRAPGLKLVVETLISSLRPIGNIVLICCAFFIIFGILGVQLFKGKFYYCEGPDTRNISTKAQC-RAAHYRWVRRKYNFDNLGQALMSLFVLSSKDGWVNIMYDGLDAVGVDQQPVQNHNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHKCRQHQEAEEARRREEKRLRRLERRRRSTFPSPEAQRRP-YYADYSPTRRSIHSLCTSHYLDLFITFIICVNVITMSMEHYNQPKSLDEALKYCNYVFTIVFVFEAALKLVAFGFRRFFKDRWNQLDLAIVLLSLMGITLEEIEMSAALPINPTIIRIMRVLRIARVLKLLKMATGMRALLDTVVQALPQVGNLGLLFMLLFFIYAALGVELFGRLECSEDNPCEGLSRHATFSNFGMAFLTLFRVSTGDNWNGIMKDTLRE--CSREDKH---CLSYLPALSPVYFVTFVLVAQFVLVNVVVAVLMKHLEESNKEAREDAELDAEIELEMAQGPGSARR 1893 HSP 2 Score: 372.859 bits (956), Expect = 1.337e-102 Identity = 237/451 (52.55%), Postives = 306/451 (67.85%), Query Frame = 1 Query: 313 YHGFYATVFHIFHQNKHPRDWCLKIITWPWFEQLSMTIIAVNCITLSMYQPCGDQNCETSKCQIMQAFDYIIFAFFTCEMVIKIIAMGFLGDLGYFGDTWNRLDMFIVIVGSIEILPSTGNNIGLTAIRTIRVLRPLRAINRIPSMRIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQMWQGVLRNRCYL------NLNESFRHPGLNLSSFYQINRTLFLNAVDKDFICSTDKNNGILKCSDIPPSIMLLSNNSL--QICKQPARPFTDNLPTKHSCVNWNQYYTDCQPGEKNPYEGAINFDNIGFAWVAIFQVISMESWVDIMYYVQDAHSFWDWIYFVALIIIGSFFMINLCLVVIASQFSETKRRETERMWIERRRFNSSNCSSISKDEPQTCYLEXXXXXXXXXXXXYRRIVKLYNQIQIRHSK-----TAQGNYQNKLKRQRK 1626 Y ATVF Q PR WCL+++ PWFE +SM +I +NC+TL M++PC D C + +C I++AFD IFAFF EMVIK++A+G G Y GDTWNRLD FIV+ G +E G+N+ L+AIRT+RVLRPLRAINR+PSMRILV LLLDTLPMLGNVLLLCFFVFFIFGI+GVQ+W G+LRNRC+L N N +F P +YQ + FICS+ ++NG+ KCS IP L +L + QP +++C+NWNQYY C+ G+ NP+ GAINFDNIG+AW+AIFQVI++E WVDIMYYV DAHSF+++IYF+ LII+GSFFMINLCLVVIA+QFSETK+RE++ M +R R S++ + S EP +CY E++K + I K+ RR ++LY + Q R K QG Q RQR+ Sbjct: 72 YPALAATVFFCLGQTTRPRSWCLRLVCNPWFEHVSMLVIMLNCVTLGMFRPCEDVECGSERCNILEAFDAFIFAFFAVEMVIKMVALGLFGQKCYLGDTWNRLDFFIVVAGMMEYS-LDGHNVSLSAIRTVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAGLLRNRCFLDSAFVRNNNLTFLRP------YYQTE-----EGEENPFICSSRRDNGMQKCSHIPGRRELRMPCTLGWEAYTQPQAEGVGA--ARNACINWNQYYNVCRSGDSNPHNGAINFDNIGYAWIAIFQVITLEGWVDIMYYVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQRESQLMREQRARHLSNDSTLASFSEPGSCYEELLKYVGHIFRKVKRRSLRLYARWQSRWRKKVDPSAVQG--QGPGHRQRR 506 HSP 3 Score: 337.806 bits (865), Expect = 8.288e-92 Identity = 189/320 (59.06%), Postives = 237/320 (74.06%), Query Frame = 1 Query: 2161 KIKTLVNDVKFQRGILIAILINTLSMGIEYHQQPVQLTQTLEFSNIVFSILFLIEMILKLIGEGILGYIKNGFNLFDGIIVVLGVIELCQQGGTSGLSILRTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKFCTIENNKRTC-DRKNFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTSSWAALYFIALMTFGNYVLFNLLVAILVEGFSSER------LDEQKLLHNYRQSLKKRRANNKQLRIMQHQSENLVLLTNSIQKDQTGENQKISSQPPVIIHTAATPMPTPRSSPY 3099 K++ +V+ F RGI++AIL+NTLSMG+EYH+QP +LT LE SNIVF+ +F +EM+LKL+ G LGYI+N +N+FDGIIVV+ V E+ Q GLS+LRTFRLLR+LKLVRF+PALR+QL V+++T+DNVATF LL+LFIFIFSILGM LFGCKF + T DRKNFDSLLW+IVTVFQILTQEDWN VLYNGM TSSWAALYF+ALMTFGNYVLFNLLVAILVEGF +E DE K ++ + K R + Q+ L + + ++ + E + S PP+I+ TAATPMPTP+SSP+ Sbjct: 785 KLRRIVDSKYFSRGIMMAILVNTLSMGVEYHEQPEELTNALEISNIVFTSMFALEMLLKLLACGPLGYIRNPYNIFDGIIVVISVWEIVGQA-DGGLSVLRTFRLLRVLKLVRFLPALRRQLVVLVKTMDNVATFCTLLMLFIFIFSILGMHLFGCKFSLKTDTGDTVPDRKNFDSLLWAIVTVFQILTQEDWNVVLYNGMASTSSWAALYFVALMTFGNYVLFNLLVAILVEGFQAEGDANRSDTDEDKTSVHFEEDFHKLR---------ELQTTELKMCSLAVTPNGHLEGRG-SLSPPLIMCTAATPMPTPKSSPF 1093 HSP 4 Score: 112.464 bits (280), Expect = 4.331e-23 Identity = 75/280 (26.79%), Postives = 138/280 (49.29%), Query Frame = 1 Query: 3862 FRQKCQHIVDKKSFDYLVLFFITLNCITLAMERPSIPPHSKERL--FLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKFYYCDGPHLQAVKTKNDCLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFH 4695 F K + IVD K F ++ I +N +++ +E P E L L ++N +FT +F EM++K+L+ G L Y+++ +NI DG +V IS+ + ++G ++ +LR FRLLR L+ +R + P L+ + L+ ++ + + F IF ILG+ LF KF LK + + NFD+L A++ +F + +++ W ++Y G+ + + WA +YF++ + + + N+ V ++VE F Sbjct: 782 FSGKLRRIVDSKYFSRGIMMAILVNTLSMGVEYHEQP----EELTNALEISNIVFTSMFALEMLLKLLACGPL----GYIRNPYNIFDGIIVVISVWE-----IVGQADGGLSVLRTFRLLRVLKLVRFL---PALRRQLVVLVKTMDNVATFCTLLMLFIFIFSILGMHLFGCKF----------------SLKTDTGDTVPDRKNFDSLLWAIVTVFQILTQEDWNVVLYNGMAST----------SSWAALYFVALMTFGNYVLFNLLVAILVEGFQ 1019 HSP 5 Score: 87.0409 bits (214), Expect = 1.943e-15 Identity = 63/241 (26.14%), Postives = 120/241 (49.79%), Query Frame = 1 Query: 2080 SYSKHRRPFNKNQNKTKRKNYLSICQQKIKTLVNDVKFQRGILIAILINTLSMGIEYHQQPVQLTQTLEFSNIVFSILFLIEMILKLIGEGILGYIKNGFNLFDGIIVVLGVIELCQQG---------GTSGLSILRTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKFCTIENNKRTCDR-KNFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTS 2772 S RRP+ + + T+R + S+C L I I +N ++M +E++ QP L + L++ N VF+I+F+ E LKL+ G + K+ +N D IV+L ++ + + + + I+R R+ R+LKL++ +R L +++ + V L +L FI++ LG+ LFG C+ +N R F + + +T+F++ T ++WN ++ + + S Sbjct: 1591 SPEAQRRPYYADYSPTRRSIH-SLCTSHYLDLF--------ITFIICVNVITMSMEHYNQPKSLDEALKYCNYVFTIVFVFEAALKLVAFGFRRFFKDRWNQLDLAIVLLSLMGITLEEIEMSAALPINPTIIRIMRVLRIARVLKLLKMATGMRALLDTVVQALPQVGNLGLLFMLLFFIYAALGVELFGRLECSEDNPCEGLSRHATFSNFGMAFLTLFRVSTGDNWNGIMKDTLRECS 1822 HSP 6 Score: 80.1073 bits (196), Expect = 2.914e-13 Identity = 61/173 (35.26%), Postives = 96/173 (55.49%), Query Frame = 1 Query: 3865 RQKCQHIVDKKSFDYLVLFFITLNCITLAMERP--SIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKG 4377 R C +V F+++ + I LNC+TL M RP + S+ L + F EM+IK+++ GL G + YL WN +D F+V +++ + GH+ + I R +R LRPLR I+R P ++++V LL +L +GN++L+C F IFGI+GVQL+ G Sbjct: 90 RSWCLRLVCNPWFEHVSMLVIMLNCVTLGMFRPCEDVECGSERCNILEAFDAFIFAFFAVEMVIKMVALGLF-GQKCYLGDTWNRLDFFIVVAGMMEYSLD---GHNVSLSAI----RTVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAG 254 HSP 7 Score: 72.7886 bits (177), Expect = 4.518e-11 Identity = 71/224 (31.70%), Postives = 117/224 (52.23%), Query Frame = 1 Query: 4798 WENYS-KWRRTINSVVTSKYFDLAIAGVIGLNVITMATEFHMMPQVLKTALKVFNYFFTSTFVXXXXXXXXXXXXXRYISDKWNQLDMMIVILSIAGVVIDEVESNFMPINPTIMRVMRVLRIARVLKLLKMASGIRALLDTVIQALPQVGNXXXXXXXXXXXXXXXXVELFG-----RLECSDINPCVGLGRHAHFENFGMAFLTLFRIATGDNWNGIMKDTL 5451 W +S K RR +V SKYF I I +N ++M E+H P+ L AL++ N FTS F LE LLKL+A G YI + +N D +IV++S+ +V + + + V+R R+ RVLKL++ +R L +++ + V L L +IF+ LG+ LFG + + D P +F++ A +T+F+I T ++WN ++ + + Sbjct: 779 WVTFSGKLRR----IVDSKYFSRGIMMAILVNTLSMGVEYHEQPEELTNALEISNIVFTSMFALEMLLKLLACGPLGYIRNPYNIFDGIIVVISVWEIV-GQADGG--------LSVLRTFRLLRVLKLVRFLPALRRQLVVLVKTMDNVATFCTLLMLFIFIFSILGMHLFGCKFSLKTDTGDTVP-----DRKNFDSLLWAIVTVFQILTQEDWNVVLYNGM 984 HSP 8 Score: 68.1662 bits (165), Expect = 9.549e-10 Identity = 61/282 (21.63%), Postives = 131/282 (46.45%), Query Frame = 1 Query: 2134 KNYLSICQQKIKTLVNDVKFQRGILIAILINTLSMGIEYHQQPVQLTQT--LEFSNIVFSILFLIEMILKLIGEGIL----GYIKNGFNLFDGIIVVLGVIELCQQGGTSGLSILRTFRLLRILKL-------VRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKFCTIEN-------NKRTCD---------RKNFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTS----------SWAALYFIALMTFGNYVLFNLLVAILVEGF 2862 +N + QK+ + F +L+ I +N +++ +E T+ L SN +F+ +F+ EM++K++ G+L Y+++ +NL DG++V++ ++++ ++G + + + L + P L+ + +I ++ + + F IF ILG+ LF KF E K C + NFD+L +++++F + +++ W ++Y+G+ W LYFI+ + ++ + N+ V ++VE F Sbjct: 1280 QNRFRVSCQKV---ITHKMFDHVVLVFIFLNCVTIALERPDIDPGSTERVFLSVSNYIFTAIFVAEMMVKVVALGLLSGEHAYLQSSWNLLDGLLVLVSLVDIVVAMASAGGAKILGVLRVLRLLRTLRPLRVISRAPGLKLVVETLISSLRPIGNIVLICCAFFIIFGILGVQLFKGKFYYCEGPDTRNISTKAQCRAAHYRWVRRKYNFDNLGQALMSLFVLSSKDGWVNIMYDGLDAVGVDQQPVQNHNPWMLLYFISFLLIVSFFVLNMFVGVVVENF 1558 HSP 9 Score: 65.4698 bits (158), Expect = 7.873e-9 Identity = 44/172 (25.58%), Postives = 81/172 (47.09%), Query Frame = 1 Query: 178 PQDNRSRRETLIGNKSDFNL-TDKSKADHCQQETDGTP---------INPNESLIYHGFYATVFHIFHQNKHPRDWCLKIITWPWFEQLSMTIIAVNCITLSMYQPCGDQNCETSKCQIMQAFDYIIFAFFTCEMVIKIIAMGFL-GDLGYFGDTWNRLDMFIVIVGSIEIL 660 P R R ++ SDF L D + D + + D + P + A ++F R C K+IT F+ + + I +NC+T+++ +P D + +++ + +YI A F EM++K++A+G L G+ Y +WN LD +V+V ++I+ Sbjct: 1211 PTKCRDRDGQVVALPSDFFLRIDSHREDAAELDDDSEDSCCLRLHKVLEPYKPQWCRSREAWALYLFSPQNRFRVSCQKVITHKMFDHVVLVFIFLNCVTIALERP--DIDPGSTERVFLSVSNYIFTAIFVAEMMVKVVALGLLSGEHAYLQSSWNLLDGLLVLVSLVDIV 1380 HSP 10 Score: 56.225 bits (134), Expect = 4.598e-6 Identity = 32/115 (27.83%), Postives = 60/115 (52.17%), Query Frame = 1 Query: 4399 PHLQAV-KTKNDCLKYSQ---------NEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFHKCQENQ 4713 P + V +N C+ ++Q + N NFDN+G A +A+F + + +GWV IMY +DA H+ + IYFI +++ +FF++N+ + V+ F + ++ + Sbjct: 325 PQAEGVGAARNACINWNQYYNVCRSGDSNPHNGAINFDNIGYAWIAIFQVITLEGWVDIMYYVMDA----------HSFYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQRE 429
BLAST of Voltage-dependent T-type calcium channel subunit alpha vs. UniProt/SwissProt
Match: sp|Q9EQ60|CAC1H_RAT (Voltage-dependent T-type calcium channel subunit alpha-1H OS=Rattus norvegicus OX=10116 GN=Cacna1h PE=2 SV=2) HSP 1 Score: 649.047 bits (1673), Expect = 0.000e+0 Identity = 391/614 (63.68%), Postives = 485/614 (78.99%), Query Frame = 1 Query: 3832 SLYVFSVDNQFRQKCQHIVDKKSFDYLVLFFITLNCITLAMERPSIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKFYYCDGPHLQAVKTKNDCLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFHKCQENQXXXXXXXXXXXXXXXXXXXXXHLRAPLYWENYSKWRRTINSVVTSKYFDLAIAGVIGLNVITMATEFHMMPQVLKTALKVFNYFFTSTFVXXXXXXXXXXXXXRYISDKWNQLDMMIVILSIAGVVIDEVESN-FMPINPTIMRVMRVLRIARVLKLLKMASGIRALLDTVIQALPQVGNXXXXXXXXXXXXXXXXVELFGRLECSDINPCVGLGRHAHFENFGMAFLTLFRIATGDNWNGIMKDTLREKCISSEDCQRNCCVSAI--IAPIYFVIFXXXXXXXXXXXXXXXXXKHLEESHKMMCDDYELEREVQRDLDE 5664 +LY+F N+ R CQ ++ K FD++VL FI LNCIT+A+ERP I P S ER FL+V+NYIFT IF EM++KV++ GLL G+ AYL+S WN++DG LV +SL+D+ + + +I G+LRV RLLRTLRPLRVISRAPGLKLVV+TL+SSLRPIGNIVLICC FFIIFGILGVQLFKGKFYYC+G + + TK +C + W +KYNFDNLGQALM+LFVLSSKDGWV IMY G+DAVG++ QP +NHN W L+YFISFLL+V+FFVLNMFVGVVVENFHKC+++QE EE RR KR RRLE++R+ + Y+ +YS RR+I+S+ TS Y DL I +I LNVITM+ E + P+ L ALK NY FT FV EA LKLVA G R+ D+WNQLD+ IV+LSI G+ ++E+E N +PINPTI+R+MRVLRIARVLKLLKMA+G+RALLDTV+QALPQVGNLGLLF LLF+I+AALGVELFGRLECS+ NPC GL RHA F NFGMAFLTLFR++TGDNWNGIMKDTLRE + ED C+S + ++P+YFV F+L+AQFVLVNVVVAVLMKHLEES+K +D E++ E++ ++ + Sbjct: 1284 ALYLFPPQNRLRVSCQKVIAHKMFDHVVLVFIFLNCITIALERPDIDPGSTERAFLSVSNYIFTAIFVVEMMVKVVALGLLWGEHAYLQSSWNVLDGLLVLVSLVDIIVAMASAGGAKILGVLRVLRLLRTLRPLRVISRAPGLKLVVETLISSLRPIGNIVLICCAFFIIFGILGVQLFKGKFYYCEGTDTRNITTKAEC-HAAHYRWVRRKYNFDNLGQALMSLFVLSSKDGWVNIMYDGLDAVGIDQQPVQNHNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHKCRQHQEAEEARRREEKRLRRLERRRRKAQRRPYYADYSHTRRSIHSLCTSHYLDLFITFIICLNVITMSMEHYNQPKSLDEALKYCNYVFTIVFVFEAALKLVAFGFRRFFKDRWNQLDLAIVLLSIMGIALEEIEMNAALPINPTIIRIMRVLRIARVLKLLKMATGMRALLDTVVQALPQVGNLGLLFMLLFFIYAALGVELFGRLECSEDNPCEGLSRHATFTNFGMAFLTLFRVSTGDNWNGIMKDTLRE--CTREDKH---CLSYLPALSPVYFVTFMLVAQFVLVNVVVAVLMKHLEESNKEAREDAEMDAEIELEMAQ 1891 HSP 2 Score: 376.711 bits (966), Expect = 6.735e-104 Identity = 241/469 (51.39%), Postives = 312/469 (66.52%), Query Frame = 1 Query: 199 RETLIGNKSDFNLTDKSKADHCQQETDGTPINPNESLIYHGFYATVFHIFHQNKHPRDWCLKIITWPWFEQLSMTIIAVNCITLSMYQPCGDQNCETSKCQIMQAFDYIIFAFFTCEMVIKIIAMGFLGDLGYFGDTWNRLDMFIVIVGSIEILPSTGNNIGLTAIRTIRVLRPLRAINRIPSMRIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQMWQGVLRNRCYL------NLNESFRHPGLNLSSFYQINRTLFLNAVDKDFICSTDKNNGILKCSDIPPSIMLLSNNSL--QICKQPARPFTDNLPTKHSCVNWNQYYTDCQPGEKNPYEGAINFDNIGFAWVAIFQVISMESWVDIMYYVQDAHSFWDWIYFVALIIIGSFFMINLCLVVIASQFSETKRRETERMWIERRRFNSSNCSSISKDEPQTCYLEXXXXXXXXXXXXYRRIVKLYNQIQIRHSK 1581 RE G+ S L +S C + P + Y ATVF Q PR WCL+++ PWFE +SM +I +NC+TL M++PC D C + +C I++AFD IFAFF EMVIK++A+G G Y GDTWNRLD FIV+ G +E G+N+ L+AIRT+RVLRPLRAINR+PSMRILV LLLDTLPMLGNVLLLCFFVFFIFGI+GVQ+W G+LRNRC+L N N +F P +YQ + FICS+ ++NG+ KCS IP L +L + QP D +++C+NWNQYY C+ GE NP+ GAINFDNIG+AW+AIFQVI++E WVDIMYYV DAHSF+++IYF+ LII+GSFFMINLCLVVIA+QFSETK+RE + M +R R+ S++ + S EP +CY E++K + I K+ RR ++LY + Q R K Sbjct: 38 REEQGGSGSGV-LAPESPGTECGADLGADEEQP---VPYPALAATVFFCLGQTTRPRSWCLRLVCNPWFEHISMLVIMLNCVTLGMFRPCEDVECRSERCSILEAFDDFIFAFFAVEMVIKMVALGLFGQKCYLGDTWNRLDFFIVMAGMME-YSLDGHNVSLSAIRTVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAGLLRNRCFLDSAFVRNNNLTFLRP------YYQTE-----EGEENPFICSSRRDNGMQKCSHIPSRRELRVQCTLGWEAYGQPQA--EDGGAGRNACINWNQYYNVCRSGEFNPHNGAINFDNIGYAWIAIFQVITLEGWVDIMYYVMDAHSFYNFIYFILLIIMGSFFMINLCLVVIATQFSETKQRENQLMREQRARYLSNDSTLASFSEPGSCYEELLKYVGHIFRKVKRRSLRLYARWQSRWRK 488 HSP 3 Score: 340.887 bits (873), Expect = 8.922e-93 Identity = 197/350 (56.29%), Postives = 241/350 (68.86%), Query Frame = 1 Query: 2074 TDSYSKHRR--PFNKNQNKTKRKNYLSICQQKIKTLVNDVKFQRGILIAILINTLSMGIEYHQQPVQLTQTLEFSNIVFSILFLIEMILKLIGEGILGYIKNGFNLFDGIIVVLGVIELCQQGGTSGLSILRTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKFCTIENNKRTC-DRKNFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTSSWAALYFIALMTFGNYVLFNLLVAILVEGFSSER------LDEQKLLHNYRQSLKKRRANNKQLRIMQHQSENLVLLTNSIQKDQTGENQKISSQPPVIIHTAATPMPTPRSSP 3096 T +S RR P K + + K++ +V+ F RGI+ AIL+NTLSMG+EYH+QP +LT LE SNIVF+ +F +EM+LKL+ G LGYI+N +N+FDGI+VV+ V E+ Q GLS+LRTFRLLR+LKLVRF+PALR+QL V++RT+DNVATF LL+LFIFIFSILGM LFGCKF ++ T DRKNFDSLLW+IVTVFQILTQEDWN VLYNGM TSSWAALYF+ALMTFGNYVLFNLLVAILVEGF +E DE K K R LR + + +L + N + + S PP+I HTAATPMPTP+SSP Sbjct: 751 TPGHSNERRRTPLRKASQPGGIGHLWASFSGKLRRIVDSKYFNRGIMAAILVNTLSMGVEYHEQPEELTNALEISNIVFTSMFALEMLLKLLACGPLGYIRNPYNIFDGIVVVISVWEIVGQA-NGGLSVLRTFRLLRVLKLVRFLPALRRQLVVLMRTMDNVATFCMLLMLFIFIFSILGMHLFGCKFSLKTDSGDTVPDRKNFDSLLWAIVTVFQILTQEDWNVVLYNGMASTSSWAALYFVALMTFGNYVLFNLLVAILVEGFQAEGDATRSDTDEDKTSTQLEGDFDKLR----DLRATEMKMYSLAVTPNGHLEGRG------SLPPPLITHTAATPMPTPKSSP 1089 HSP 4 Score: 115.931 bits (289), Expect = 3.503e-24 Identity = 76/280 (27.14%), Postives = 140/280 (50.00%), Query Frame = 1 Query: 3862 FRQKCQHIVDKKSFDYLVLFFITLNCITLAMERPSIPPHSKERL--FLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKFYYCDGPHLQAVKTKNDCLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFH 4695 F K + IVD K F+ ++ I +N +++ +E P E L L ++N +FT +F EM++K+L+ G L Y+++ +NI DG +V IS+ + ++G +N +LR FRLLR L+ +R + P L+ + L+ ++ + ++ F IF ILG+ LF KF LK + + NFD+L A++ +F + +++ W ++Y G+ + + WA +YF++ + + + N+ V ++VE F Sbjct: 779 FSGKLRRIVDSKYFNRGIMAAILVNTLSMGVEYHEQP----EELTNALEISNIVFTSMFALEMLLKLLACGPL----GYIRNPYNIFDGIVVVISVWE-----IVGQANGGLSVLRTFRLLRVLKLVRFL---PALRRQLVVLMRTMDNVATFCMLLMLFIFIFSILGMHLFGCKF----------------SLKTDSGDTVPDRKNFDSLLWAIVTVFQILTQEDWNVVLYNGMAST----------SSWAALYFVALMTFGNYVLFNLLVAILVEGFQ 1016 HSP 5 Score: 83.1889 bits (204), Expect = 3.304e-14 Identity = 68/261 (26.05%), Postives = 127/261 (48.66%), Query Frame = 1 Query: 2101 PFNKNQNKTKRKNYLSICQQKIKTLVNDVKFQRGILIAILINTLSMGIEYHQQPVQLTQTLEFSNIVFSILFLIEMILKLIGEGILGYIKNGFNLFDGIIVVLGVIELCQQG---------GTSGLSILRTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKFCTIENNKRTCDR-KNFDSLLWSIVTVFQILTQEDWNTVLYNGM---TRTSSWAALYFIALMTFGNYVLFNLLVA 2844 P+ + + T+R + S+C L I I +N ++M +E++ QP L + L++ N VF+I+F+ E LKL+ G + K+ +N D IV+L ++ + + + + I+R R+ R+LKL++ +R L +++ + V L +L FI++ LG+ LFG C+ +N R F + + +T+F++ T ++WN ++ + + TR Y AL Y + +LVA Sbjct: 1603 PYYADYSHTRRSIH-SLCTSHYLDLF--------ITFIICLNVITMSMEHYNQPKSLDEALKYCNYVFTIVFVFEAALKLVAFGFRRFFKDRWNQLDLAIVLLSIMGIALEEIEMNAALPINPTIIRIMRVLRIARVLKLLKMATGMRALLDTVVQALPQVGNLGLLFMLLFFIYAALGVELFGRLECSEDNPCEGLSRHATFTNFGMAFLTLFRVSTGDNWNGIMKDTLRECTREDKHCLSYLPALSPV--YFVTFMLVA 1852 HSP 6 Score: 82.4185 bits (202), Expect = 5.472e-14 Identity = 61/173 (35.26%), Postives = 96/173 (55.49%), Query Frame = 1 Query: 3865 RQKCQHIVDKKSFDYLVLFFITLNCITLAMERP--SIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKG 4377 R C +V F+++ + I LNC+TL M RP + S+ L + F EM+IK+++ GL G + YL WN +D F+V +++ + GH+ + I R +R LRPLR I+R P ++++V LL +L +GN++L+C F IFGI+GVQL+ G Sbjct: 90 RSWCLRLVCNPWFEHISMLVIMLNCVTLGMFRPCEDVECRSERCSILEAFDDFIFAFFAVEMVIKMVALGLF-GQKCYLGDTWNRLDFFIVMAGMMEYSLD---GHNVSLSAI----RTVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAG 254 HSP 7 Score: 74.7146 bits (182), Expect = 1.101e-11 Identity = 71/224 (31.70%), Postives = 121/224 (54.02%), Query Frame = 1 Query: 4798 WENYS-KWRRTINSVVTSKYFDLAIAGVIGLNVITMATEFHMMPQVLKTALKVFNYFFTSTFVXXXXXXXXXXXXXRYISDKWNQLDMMIVILSIAGVVIDEVESNFMPINPTIMRVMRVLRIARVLKLLKMASGIRALLDTVIQALPQVGNXXXXXXXXXXXXXXXXVELFG-----RLECSDINPCVGLGRHAHFENFGMAFLTLFRIATGDNWNGIMKDTL 5451 W ++S K RR +V SKYF+ I I +N ++M E+H P+ L AL++ N FTS F LE LLKL+A G YI + +N D ++V++S+ +V ++N + V+R R+ RVLKL++ +R L +++ + V +L L +IF+ LG+ LFG + + D P +F++ A +T+F+I T ++WN ++ + + Sbjct: 776 WASFSGKLRR----IVDSKYFNRGIMAAILVNTLSMGVEYHEQPEELTNALEISNIVFTSMFALEMLLKLLACGPLGYIRNPYNIFDGIVVVISVWEIV---GQAN------GGLSVLRTFRLLRVLKLVRFLPALRRQLVVLMRTMDNVATFCMLLMLFIFIFSILGMHLFGCKFSLKTDSGDTVP-----DRKNFDSLLWAIVTVFQILTQEDWNVVLYNGM 981 HSP 8 Score: 70.4774 bits (171), Expect = 2.289e-10 Identity = 65/282 (23.05%), Postives = 138/282 (48.94%), Query Frame = 1 Query: 2134 KNYLSICQQKIKTLVNDVKFQRGILIAILINTLSMGIEYHQQPVQLTQT--LEFSNIVFSILFLIEMILKLIGEGIL----GYIKNGFNLFDGIIVVLGVIELCQQGGTSGLSIL-------RTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKFCTIEN-------NKRTCD---------RKNFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTS----------SWAALYFIALMTFGNYVLFNLLVAILVEGF 2862 +N L + QK+ + F +L+ I +N +++ +E T+ L SN +F+ +F++EM++K++ G+L Y+++ +N+ DG++V++ ++++ ++G + + R R LR L+++ P L+ + +I ++ + + F IF ILG+ LF KF E K C + NFD+L +++++F + +++ W ++Y+G+ W LYFI+ + ++ + N+ V ++VE F Sbjct: 1291 QNRLRVSCQKV---IAHKMFDHVVLVFIFLNCITIALERPDIDPGSTERAFLSVSNYIFTAIFVVEMMVKVVALGLLWGEHAYLQSSWNVLDGLLVLVSLVDIIVAMASAGGAKILGVLRVLRLLRTLRPLRVISRAPGLKLVVETLISSLRPIGNIVLICCAFFIIFGILGVQLFKGKFYYCEGTDTRNITTKAECHAAHYRWVRRKYNFDNLGQALMSLFVLSSKDGWVNIMYDGLDAVGIDQQPVQNHNPWMLLYFISFLLIVSFFVLNMFVGVVVENF 1569 HSP 9 Score: 63.929 bits (154), Expect = 2.348e-8 Identity = 33/118 (27.97%), Postives = 64/118 (54.24%), Query Frame = 1 Query: 334 VFHIFHQNKHPRDWCLKIITWPWFEQLSMTIIAVNCITLSMYQPCGDQNCETSKCQIMQAFDYIIFAFFTCEMVIKIIAMGFL-GDLGYFGDTWNRLDMFIVIVGSIEILPSTGNNIG 684 ++F R C K+I F+ + + I +NCIT+++ +P D + +++ + +YI A F EM++K++A+G L G+ Y +WN LD +V+V ++I+ + + G Sbjct: 1284 ALYLFPPQNRLRVSCQKVIAHKMFDHVVLVFIFLNCITIALERP--DIDPGSTERAFLSVSNYIFTAIFVVEMMVKVVALGLLWGEHAYLQSSWNVLDGLLVLVSLVDIIVAMASAGG 1399 HSP 10 Score: 55.8398 bits (133), Expect = 5.261e-6 Identity = 31/86 (36.05%), Postives = 50/86 (58.14%), Query Frame = 1 Query: 4462 NQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFH--KCQENQ 4713 N NFDN+G A +A+F + + +GWV IMY +DA H+ + IYFI +++ +FF++N+ + V+ F K +ENQ Sbjct: 356 NGAINFDNIGYAWIAIFQVITLEGWVDIMYYVMDA----------HSFYNFIYFILLIIMGSFFMINLCLVVIATQFSETKQRENQ 431
BLAST of Voltage-dependent T-type calcium channel subunit alpha vs. UniProt/SwissProt
Match: sp|O88427|CAC1H_MOUSE (Voltage-dependent T-type calcium channel subunit alpha-1H OS=Mus musculus OX=10090 GN=Cacna1h PE=1 SV=3) HSP 1 Score: 647.121 bits (1668), Expect = 0.000e+0 Identity = 401/653 (61.41%), Postives = 498/653 (76.26%), Query Frame = 1 Query: 3814 AKRYYHSLYVFSVDNQFRQKCQHIVDKKSFDYLVLFFITLNCITLAMERPSIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKFYYCDGPHLQAVKTKNDCLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFHKCQENQXXXXXXXXXXXXXXXXXXXXXHL-------RAPLYWENYSKWRRTINSVVTSKYFDLAIAGVIGLNVITMATEFHMMPQVLKTALKVFNYFFTSTFVXXXXXXXXXXXXXRYISDKWNQLDMMIVILSIAGVVIDEVESNF-MPINPTIMRVMRVLRIARVLKLLKMASGIRALLDTVIQALPQVGNXXXXXXXXXXXXXXXXVELFGRLECSDINPCVGLGRHAHFENFGMAFLTLFRIATGDNWNGIMKDTLREKCISSEDCQRNCCVSAI--IAPIYFVIFXXXXXXXXXXXXXXXXXKHLEESHKMMCDDYELEREVQRDLDE----EAKELAREKQLKDEENNENTLI 5730 + R +LY+F N+ R CQ ++ K FD++VL FI LNCIT+A+ERP I P S ER FL+V+NYIFT IF EM++KV++ GLL G+ AYL+S WN++DG LV +SL+D+ + + +I G+LRV RLLRTLRPLRVISRAPGLKLVV+TL+SSLRPIGNIVLICC FFIIFGILGVQLFKGKFYYC+G + + TK +C + W +KYNFDNLGQALM+LFVLSSKDGWV IMY G+DAVG++ QP +NHN W L+YFISFLL+V+FFVLNMFVGVVVENFHKC+++QE EE RR KR RRLE++R+ R P Y+ +YS RR+I+S+ TS Y DL I +I LNVITM+ E + P+ L ALK NY FT FV EA LKLVA G R+ D+WNQLD+ IV+LSI G+ ++E+E N +PINPTI+R+MRVLRIARVLKLLKMA+G+RALLDTV+QALPQVGNLGLLF LLF+I+AALGVELFGRLECS+ NPC GL RHA F NFGMAFLTLFR++TGDNWNGIMKDTLRE + ED C+S + ++P+YFV FVL+AQFVLVNVVVAVLMKHLEES+K +D E++ E++ ++ + + A+E Q E + N L+ Sbjct: 1278 SSRESWALYLFPPQNRLRVSCQKVIAHKMFDHVVLVFIFLNCITIALERPDIDPGSTERAFLSVSNYIFTAIFVVEMMVKVVALGLLWGEHAYLQSSWNVLDGLLVLVSLVDIIVAVASAGGAKILGVLRVLRLLRTLRPLRVISRAPGLKLVVETLISSLRPIGNIVLICCAFFIIFGILGVQLFKGKFYYCEGTDTRNITTKAEC-HAAHYRWVRRKYNFDNLGQALMSLFVLSSKDGWVNIMYDGLDAVGIDQQPVQNHNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHKCRQHQEAEEARRREEKRLRRLERRRRSTFPNPEAQRRP-YYADYSHTRRSIHSLCTSHYLDLFITFIICLNVITMSMEHYNQPKSLDEALKYCNYVFTIVFVFEAALKLVAFGFRRFFKDRWNQLDLAIVLLSIMGIALEEIEMNAALPINPTIIRIMRVLRIARVLKLLKMATGMRALLDTVVQALPQVGNLGLLFMLLFFIYAALGVELFGRLECSEDNPCEGLSRHATFTNFGMAFLTLFRVSTGDNWNGIMKDTLRE--CTREDKH---CLSYLPALSPVYFVTFVLVAQFVLVNVVVAVLMKHLEESNKEAREDAEMDAEIELEIAQGSTAQPPSTAQESQ-GTEPDTPNLLV 1922 HSP 2 Score: 374.4 bits (960), Expect = 3.674e-103 Identity = 240/469 (51.17%), Postives = 312/469 (66.52%), Query Frame = 1 Query: 199 RETLIGNKSDFNLTDKSKADHCQQETDGTPINPNESLIYHGFYATVFHIFHQNKHPRDWCLKIITWPWFEQLSMTIIAVNCITLSMYQPCGDQNCETSKCQIMQAFDYIIFAFFTCEMVIKIIAMGFLGDLGYFGDTWNRLDMFIVIVGSIEILPSTGNNIGLTAIRTIRVLRPLRAINRIPSMRIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQMWQGVLRNRCYL------NLNESFRHPGLNLSSFYQINRTLFLNAVDKDFICSTDKNNGILKCSDIPPSIMLLSNNSL--QICKQPARPFTDNLPTKHSCVNWNQYYTDCQPGEKNPYEGAINFDNIGFAWVAIFQVISMESWVDIMYYVQDAHSFWDWIYFVALIIIGSFFMINLCLVVIASQFSETKRRETERMWIERRRFNSSNCSSISKDEPQTCYLEXXXXXXXXXXXXYRRIVKLYNQIQIRHSK 1581 RE G+ S L +S C + P + Y ATVF Q PR WCL++++ WFE +SM +I +NC+TL M++PC D C + +C I++AFD IFAFF EMVIK++A+G G Y GDTWNRLD FIV+ G +E G+N+ L+AIRT+RVLRPLRAINR+PSMRILV LLLDTLPMLGNVLLLCFFVFFIFGI+GVQ+W G+LRNRC+L N N +F P +YQ + FICS+ ++NG+ KCS IP L +L + QP D +++C+NWNQYY C+ GE NP+ GAINFDNIG+AW+AIFQVI++E WVDIMYYV DAHSF+++IYF+ LII+GSFFMINLCLVVIA+QFSETK+RE + M +R R+ S++ + S EP +CY E++K + I K+ RR ++LY + Q R K Sbjct: 38 REEQRGSGSSV-LAPESPGTECGADLGADEEQP---VPYPALAATVFFCLGQTTRPRSWCLRLVSRRWFEHISMLVIMLNCVTLGMFRPCEDVECRSERCSILEAFDDFIFAFFAVEMVIKMVALGLFGQKCYLGDTWNRLDFFIVMAGMME-YSLDGHNVSLSAIRTVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAGLLRNRCFLDSAFVRNNNLTFLRP------YYQTE-----EGEENPFICSSRRDNGMQKCSHIPSRRELRVQCTLGWEAYGQPQA--EDGGAGRNACINWNQYYNVCRSGEFNPHNGAINFDNIGYAWIAIFQVITLEGWVDIMYYVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQRENQLMREQRARYLSNDSTLASFSEPGSCYEELLKYVGHIFRKVKRRSLRLYARWQSRWRK 488 HSP 3 Score: 338.191 bits (866), Expect = 6.480e-92 Identity = 190/324 (58.64%), Postives = 234/324 (72.22%), Query Frame = 1 Query: 2161 KIKTLVNDVKFQRGILIAILINTLSMGIEYHQQPVQLTQTLEFSNIVFSILFLIEMILKLIGEGILGYIKNGFNLFDGIIVVLGVIELCQQGGTSGLSILRTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKFCTIENNKRTC-DRKNFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTSSWAALYFIALMTFGNYVLFNLLVAILVEGFSSER------LDEQKLLHNYRQSLKKRRANNKQLRIMQHQSENLVLLTNSIQKDQTGENQKISSQPPVIIHTAATPMPTPRSSPYNELV 3111 K++ +V+ F RGI+ AIL+NTLSMG+EYH+QP +LT LE SNIVF+ +F +EM+LKL+ G LGYI+N +N+FDGI+V++ V E+ Q GLS+LRTFRLLR+LKLVRF+PALR+QL V++RT+DNVATF LL+LFIFIFSILGM LFGCKF ++ T DRKNFDSLLW+IVTVFQILTQEDWN VLYNGM TSSWAALYF+ALMTFGNYVLFNLLVAILVEGF +E DE K + + K LR +Q + L + G S PP+I HTAATPMPTP+SSP+ ++ Sbjct: 782 KLRRIVDSKYFNRGIMAAILVNTLSMGVEYHEQPDELTNALEISNIVFTSMFALEMLLKLLACGPLGYIRNPYNIFDGIVVIISVWEIVGQA-DGGLSVLRTFRLLRVLKLVRFLPALRRQLVVLMRTMDNVATFCMLLMLFIFIFSILGMHLFGCKFSLKTDSGDTVPDRKNFDSLLWAIVTVFQILTQEDWNVVLYNGMASTSSWAALYFVALMTFGNYVLFNLLVAILVEGFQAEGDATRSDTDEDKTSTHLEEDFDK-------LRDVQATEMKMYSLAVTPNGHLEGRG---SLPPPLITHTAATPMPTPKSSPHLDMA 1094 HSP 4 Score: 114.39 bits (285), Expect = 9.070e-24 Identity = 73/278 (26.26%), Postives = 138/278 (49.64%), Query Frame = 1 Query: 3862 FRQKCQHIVDKKSFDYLVLFFITLNCITLAMERPSIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKFYYCDGPHLQAVKTKNDCLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFH 4695 F K + IVD K F+ ++ I +N +++ +E P L ++N +FT +F EM++K+L+ G L Y+++ +NI DG +V IS+ + ++G ++ +LR FRLLR L+ +R + P L+ + L+ ++ + ++ F IF ILG+ LF KF LK + + NFD+L A++ +F + +++ W ++Y G+ + + WA +YF++ + + + N+ V ++VE F Sbjct: 779 FSSKLRRIVDSKYFNRGIMAAILVNTLSMGVEYHEQPDELTNAL--EISNIVFTSMFALEMLLKLLACGPL----GYIRNPYNIFDGIVVIISVWE-----IVGQADGGLSVLRTFRLLRVLKLVRFL---PALRRQLVVLMRTMDNVATFCMLLMLFIFIFSILGMHLFGCKF----------------SLKTDSGDTVPDRKNFDSLLWAIVTVFQILTQEDWNVVLYNGMAST----------SSWAALYFVALMTFGNYVLFNLLVAILVEGFQ 1016 HSP 5 Score: 87.4261 bits (215), Expect = 1.449e-15 Identity = 66/250 (26.40%), Postives = 123/250 (49.20%), Query Frame = 1 Query: 2092 HRRPFNKNQNKTKRKNYLSICQQKIKTLVNDVKFQRGILIAILINTLSMGIEYHQQPVQLTQTLEFSNIVFSILFLIEMILKLIGEGILGYIKNGFNLFDGIIVVLGVIELCQQG---------GTSGLSILRTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKFCTIENNKRTCDR-KNFDSLLWSIVTVFQILTQEDWNTVLYNGM---TRTSSWAALYFIAL 2802 RRP+ + + T+R + S+C L I I +N ++M +E++ QP L + L++ N VF+I+F+ E LKL+ G + K+ +N D IV+L ++ + + + + I+R R+ R+LKL++ +R L +++ + V L +L FI++ LG+ LFG C+ +N R F + + +T+F++ T ++WN ++ + + TR Y AL Sbjct: 1606 QRRPYYADYSHTRRSIH-SLCTSHYLDLF--------ITFIICLNVITMSMEHYNQPKSLDEALKYCNYVFTIVFVFEAALKLVAFGFRRFFKDRWNQLDLAIVLLSIMGIALEEIEMNAALPINPTIIRIMRVLRIARVLKLLKMATGMRALLDTVVQALPQVGNLGLLFMLLFFIYAALGVELFGRLECSEDNPCEGLSRHATFTNFGMAFLTLFRVSTGDNWNGIMKDTLRECTREDKHCLSYLPAL 1846 HSP 6 Score: 85.8853 bits (211), Expect = 5.070e-15 Identity = 61/173 (35.26%), Postives = 98/173 (56.65%), Query Frame = 1 Query: 3865 RQKCQHIVDKKSFDYLVLFFITLNCITLAMERP--SIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKG 4377 R C +V ++ F+++ + I LNC+TL M RP + S+ L + F EM+IK+++ GL G + YL WN +D F+V +++ + GH+ + I R +R LRPLR I+R P ++++V LL +L +GN++L+C F IFGI+GVQL+ G Sbjct: 90 RSWCLRLVSRRWFEHISMLVIMLNCVTLGMFRPCEDVECRSERCSILEAFDDFIFAFFAVEMVIKMVALGLF-GQKCYLGDTWNRLDFFIVMAGMMEYSLD---GHNVSLSAI----RTVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAG 254 HSP 7 Score: 74.7146 bits (182), Expect = 1.030e-11 Identity = 71/224 (31.70%), Postives = 119/224 (53.12%), Query Frame = 1 Query: 4798 WENYS-KWRRTINSVVTSKYFDLAIAGVIGLNVITMATEFHMMPQVLKTALKVFNYFFTSTFVXXXXXXXXXXXXXRYISDKWNQLDMMIVILSIAGVVIDEVESNFMPINPTIMRVMRVLRIARVLKLLKMASGIRALLDTVIQALPQVGNXXXXXXXXXXXXXXXXVELFG-----RLECSDINPCVGLGRHAHFENFGMAFLTLFRIATGDNWNGIMKDTL 5451 W ++S K RR +V SKYF+ I I +N ++M E+H P L AL++ N FTS F LE LLKL+A G YI + +N D ++VI+S+ +V + + + V+R R+ RVLKL++ +R L +++ + V +L L +IF+ LG+ LFG + + D P +F++ A +T+F+I T ++WN ++ + + Sbjct: 776 WASFSSKLRR----IVDSKYFNRGIMAAILVNTLSMGVEYHEQPDELTNALEISNIVFTSMFALEMLLKLLACGPLGYIRNPYNIFDGIVVIISVWEIV-GQADGG--------LSVLRTFRLLRVLKLVRFLPALRRQLVVLMRTMDNVATFCMLLMLFIFIFSILGMHLFGCKFSLKTDSGDTVP-----DRKNFDSLLWAIVTVFQILTQEDWNVVLYNGM 981 HSP 8 Score: 70.4774 bits (171), Expect = 2.123e-10 Identity = 65/282 (23.05%), Postives = 138/282 (48.94%), Query Frame = 1 Query: 2134 KNYLSICQQKIKTLVNDVKFQRGILIAILINTLSMGIEYHQQPVQLTQT--LEFSNIVFSILFLIEMILKLIGEGIL----GYIKNGFNLFDGIIVVLGVIELCQQGGTSGLSIL-------RTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKFCTIEN-------NKRTCD---------RKNFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTS----------SWAALYFIALMTFGNYVLFNLLVAILVEGF 2862 +N L + QK+ + F +L+ I +N +++ +E T+ L SN +F+ +F++EM++K++ G+L Y+++ +N+ DG++V++ ++++ ++G + + R R LR L+++ P L+ + +I ++ + + F IF ILG+ LF KF E K C + NFD+L +++++F + +++ W ++Y+G+ W LYFI+ + ++ + N+ V ++VE F Sbjct: 1291 QNRLRVSCQKV---IAHKMFDHVVLVFIFLNCITIALERPDIDPGSTERAFLSVSNYIFTAIFVVEMMVKVVALGLLWGEHAYLQSSWNVLDGLLVLVSLVDIIVAVASAGGAKILGVLRVLRLLRTLRPLRVISRAPGLKLVVETLISSLRPIGNIVLICCAFFIIFGILGVQLFKGKFYYCEGTDTRNITTKAECHAAHYRWVRRKYNFDNLGQALMSLFVLSSKDGWVNIMYDGLDAVGIDQQPVQNHNPWMLLYFISFLLIVSFFVLNMFVGVVVENF 1569 HSP 9 Score: 64.3142 bits (155), Expect = 1.795e-8 Identity = 33/118 (27.97%), Postives = 64/118 (54.24%), Query Frame = 1 Query: 334 VFHIFHQNKHPRDWCLKIITWPWFEQLSMTIIAVNCITLSMYQPCGDQNCETSKCQIMQAFDYIIFAFFTCEMVIKIIAMGFL-GDLGYFGDTWNRLDMFIVIVGSIEILPSTGNNIG 684 ++F R C K+I F+ + + I +NCIT+++ +P D + +++ + +YI A F EM++K++A+G L G+ Y +WN LD +V+V ++I+ + + G Sbjct: 1284 ALYLFPPQNRLRVSCQKVIAHKMFDHVVLVFIFLNCITIALERP--DIDPGSTERAFLSVSNYIFTAIFVVEMMVKVVALGLLWGEHAYLQSSWNVLDGLLVLVSLVDIIVAVASAGG 1399 HSP 10 Score: 55.8398 bits (133), Expect = 6.173e-6 Identity = 31/86 (36.05%), Postives = 50/86 (58.14%), Query Frame = 1 Query: 4462 NQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFH--KCQENQ 4713 N NFDN+G A +A+F + + +GWV IMY +DA H+ + IYFI +++ +FF++N+ + V+ F K +ENQ Sbjct: 356 NGAINFDNIGYAWIAIFQVITLEGWVDIMYYVMDA----------HSFYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQRENQ 431
BLAST of Voltage-dependent T-type calcium channel subunit alpha vs. UniProt/SwissProt
Match: sp|Q9Z0Y8|CAC1I_RAT (Voltage-dependent T-type calcium channel subunit alpha-1I OS=Rattus norvegicus OX=10116 GN=Cacna1i PE=1 SV=3) HSP 1 Score: 637.876 bits (1644), Expect = 0.000e+0 Identity = 389/611 (63.67%), Postives = 487/611 (79.71%), Query Frame = 1 Query: 3832 SLYVFSVDNQFRQKCQHIVDKKSFDYLVLFFITLNCITLAMERPSIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKFYYCDGPHLQAVKTKNDCLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFHKCQENQXXXXXXXXXXXXXXXXXXXXXHLRAPLYWENYSKWRRTINSVVTSKYFDLAIAGVIGLNVITMATEFHMMPQVLKTALKVFNYFFTSTFVXXXXXXXXXXXXXRYISDKWNQLDMMIVILSIAGVVIDEVESN-FMPINPTIMRVMRVLRIARVLKLLKMASGIRALLDTVIQALPQVGNXXXXXXXXXXXXXXXXVELFGRLECSDINPCVGLGRHAHFENFGMAFLTLFRIATGDNWNGIMKDTLREKCISSEDCQRNCCVS-AIIAPIYFVIFXXXXXXXXXXXXXXXXXKHLEESHKMMCDDYELEREVQRDL 5658 S+Y+FS +N+FR CQ I+ K FDY+VL FI LNCIT+A+ERP I S ER+FLTV+NYIFT IF GEM +KV+S GL G+QAYL+S WN++DGFLVF+S++D+ +++ +I G+LRV RLLRTLRPLRVISRAPGLKLVV+TL+SSL+PIGNIVLICC FFIIFGILGVQLFKGKFY+C G + + ++DC+ + W + KYNFDNLGQALM+LFVL+SKDGWV IMY G+DAV V+ QP NHN W L+YFISFLL+V+FFVLNMFVGVVVENFHKC+++QE EE RR KR RRLEKKR+ + Y+ Y R I+S+ TS Y D+ I +I LNV+TM+ E + P L+TALK NY FT+ FVLEA+LKLVA GL R+ D+WNQLD+ IV+LS+ G+ ++E+E N +PINPTI+R+MRVLRIARVLKLLKMA+G+RALLDTV+QALPQVGNLGLLF LLF+I+AALGVELFG+L C+D NPC G+ RHA FENFGMAFLTLF+++TGDNWNGIMKDTLR+ C E R+C S ++P+YFV FVL AQFVL+NVVVAVLMKHL++S+K +D E++ E++ ++ Sbjct: 1108 SVYLFSPENKFRILCQTIIAHKLFDYVVLAFIFLNCITIALERPQIEAGSTERIFLTVSNYIFTAIFVGEMTLKVVSLGLYFGEQAYLRSSWNVLDGFLVFVSIIDIVVSVASAGGAKILGVLRVLRLLRTLRPLRVISRAPGLKLVVETLISSLKPIGNIVLICCAFFIIFGILGVQLFKGKFYHCLGVDTRNITNRSDCVA-ANYRWVHHKYNFDNLGQALMSLFVLASKDGWVNIMYNGLDAVAVDQQPVTNHNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHKCRQHQEAEEARRREEKRLRRLEKKRRKAQRLPYYATYCPTRLLIHSMCTSHYLDIFITFIICLNVVTMSLEHYNQPTSLETALKYCNYMFTTVFVLEAVLKLVAFGLRRFFKDRWNQLDLAIVLLSVMGITLEEIEINAALPINPTIIRIMRVLRIARVLKLLKMATGMRALLDTVVQALPQVGNLGLLFMLLFFIYAALGVELFGKLVCNDENPCEGMSRHATFENFGMAFLTLFQVSTGDNWNGIMKDTLRD-CTHDE---RSCLSSLQFVSPLYFVSFVLTAQFVLINVVVAVLMKHLDDSNKEAQEDAEMDAEIELEM 1713 HSP 2 Score: 360.918 bits (925), Expect = 5.630e-99 Identity = 235/481 (48.86%), Postives = 304/481 (63.20%), Query Frame = 1 Query: 298 NESLIYHGFYATVFHIFHQNKHPRDWCLKIITWPWFEQLSMTIIAVNCITLSMYQPCGDQNCETSKCQIMQAFDYIIFAFFTCEMVIKIIAMGFLGDLGYFGDTWNRLDMFIVIVGSIEILPSTGNNIGLTAIRTIRVLRPLRAINRIPSMRIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQMWQGVLRNRCYLNLNESFRHPGLNLSSFYQINRTLFLNAVDKDFICSTDKNNGILKCSDIPPSIMLLSNNSLQIC--KQPARPFT---DNLPTKHSCVNWNQYYTDCQPGEKNPYEGAINFDNIGFAWVAIFQVISMESWVDIMYYVQDAHSFWDWIYFVALIIIGSFFMINLCLVVIASQFSETKRRETERMWIERRRFNSSNCSSISKDEPQTCYLEXXXXXXXXXXXXYRRIVKLYNQIQIRHSKTAQGN----YQNKLKRQRKHCNVCLNSRSQFPIDDHCHLYSIVNTISG 1713 N + + F Q PR+WC+K++ PWFE +SM +I +NC+TL MYQPC D C + +C+I+Q FD IF FF EMV+K++A+G G Y GDTWNRLD FIV+ G +E NI L+AIRT+RVLRPL+AINR+PSMRILV LLLDTLPMLGNVLLLCFFVFFIFGIIGVQ+W G+LRNRC+L N + + + L +YQ + FICS +NGI+ C +IPP L + C K F +L CVNWN+YY C+ G NP++GAINFDNIG+AW+ IFQVI++E WV+IMYYV DAHSF+++IYF+ LII+GSFFMINLCLVVIA+QFSETK+RE M +R+R+ SS+ + S EP CY EI + + I+ K RR + LY +Q R G ++ HC +C P+D H ++V IS Sbjct: 44 NPDVPHPDLAPVAFFCLRQTTSPRNWCIKMVCNPWFECVSMLVILLNCVTLGMYQPCDDMECLSDRCKILQVFDDFIFIFFAMEMVLKMVALGIFGKKCYLGDTWNRLDFFIVMAGMVEYSLDL-QNINLSAIRTVRVLRPLKAINRVPSMRILVNLLLDTLPMLGNVLLLCFFVFFIFGIIGVQLWAGLLRNRCFLEENFTIQG-DVALPPYYQPEED-----DEMPFICSLTGDNGIMGCHEIPP----LKEQGRECCLSKDDVYDFGAGRQDLNASGLCVNWNRYYNVCRTGNANPHKGAINFDNIGYAWIVIFQVITLEGWVEIMYYVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQREHRLMLEQRQRYLSSS-TVASYAEPGDCYEEIFQYVCHILRKAKRRALGLYQALQNRRQAMGPGTPAPAKPGPHAKEPSHCKLC---PRHSPLDPTPH--TLVQPISA 507 HSP 3 Score: 273.092 bits (697), Expect = 4.647e-72 Identity = 169/317 (53.31%), Postives = 223/317 (70.35%), Query Frame = 1 Query: 2155 QQKIKTLVNDVKFQRGILIAILINTLSMGIEYHQQPVQLTQTLEFSNIVFSILFLIEMILKLIGEGILGYIKNGFNLFDGIIVVLGVIELCQQGGTSGLSILRTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKFCTIENNKRTC-DRKNFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTSSWAALYFIALMTFGNYVLFNLLVAILVEGFSSER------LDEQKLLHNYRQ--SLKKRRANNKQLRIMQ-------HQSENLVLLTNSIQKDQTGENQKISSQP-PVII 3054 ++K++ +V+ F RGI++AIL+NT+SMGIE+H+QP +LT LE N+VF+ +F +EMILKL G+ Y++N +N+FD IIV++ + E+ Q GLS+LRTFRLLR+LKLVRFMPALR+QL V+++T+DNVATF LL+LFIFIFSILGM +FGCKF + T DRKNFDSLLW+IVTVFQILTQEDWN VLYNGM T+ WA+LYF+ALMTFGNYVLFNLLVAILVEGF +E DE + N + L + N++ L++ H +L L + G ++S QP PV++ Sbjct: 588 REKLRGIVDSKYFNRGIMMAILVNTVSMGIEHHEQPEELTNILEICNVVFTSMFALEMILKLAAFGLFDYLRNPYNIFDSIIVIISIWEIVGQA-DGGLSVLRTFRLLRVLKLVRFMPALRRQLVVLMKTMDNVATFCMLLMLFIFIFSILGMHIFGCKFSLRTDTGDTVPDRKNFDSLLWAIVTVFQILTQEDWNVVLYNGMASTTPWASLYFVALMTFGNYVLFNLLVAILVEGFQAEGDANRSYSDEDQSSSNLEEFDKLPEGLDNSRDLKLCPIPMTPNGHLDPSLPLGAHLGPAGTMGTAPRLSLQPDPVLV 903 HSP 4 Score: 95.9005 bits (237), Expect = 3.895e-18 Identity = 64/250 (25.60%), Postives = 128/250 (51.20%), Query Frame = 1 Query: 2203 ILIAILINTLSMGIEYHQQPVQLTQTLEFSNIVFSILFLIEMILKLIGEGILGYIKNGFNLFDGIIVVLGVIELCQQG---------GTSGLSILRTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKFCTIENNKRTCDR-KNFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTSS-----------WAALYFIALMTFGNYVLFNLLVAILVEGFSSERLDEQK 2889 I I +N ++M +E++ QP L L++ N +F+ +F++E +LKL+ G+ + K+ +N D IV+L V+ + + + + I+R R+ R+LKL++ +R L +++ + V L +L FI++ LG+ LFG C EN R F++ + +T+FQ+ T ++WN ++ + + + + LYF++ + +VL N++VA+L++ + Q+ Sbjct: 1452 ITFIICLNVVTMSLEHYNQPTSLETALKYCNYMFTTVFVLEAVLKLVAFGLRRFFKDRWNQLDLAIVLLSVMGITLEEIEINAALPINPTIIRIMRVLRIARVLKLLKMATGMRALLDTVVQALPQVGNLGLLFMLLFFIYAALGVELFGKLVCNDENPCEGMSRHATFENFGMAFLTLFQVSTGDNWNGIMKDTLRDCTHDERSCLSSLQFVSPLYFVSFVLTAQFVLINVVVAVLMKHLDDSNKEAQE 1701 HSP 5 Score: 93.9745 bits (232), Expect = 1.560e-17 Identity = 70/279 (25.09%), Postives = 134/279 (48.03%), Query Frame = 1 Query: 3865 RQKCQHIVDKKSFDYLVLFFITLNCITLAMERPSIPPHSKERL--FLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKFYYCDGPHLQAVKTKNDCLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFH 4695 R+K + IVD K F+ ++ I +N +++ +E P E L L + N +FT +F EMI+K+ + GL YL++ +NI ++ + I ++G ++ +LR FRLLR L+ +R + P L+ + L+ ++ + ++ F IF ILG+ +F KF L+ + + NFD+L A++ +F + +++ W ++Y G+ + WA +YF++ + + + N+ V ++VE F Sbjct: 588 REKLRGIVDSKYFNRGIMMAILVNTVSMGIEHHEQP----EELTNILEICNVVFTSMFALEMILKLAAFGLF----DYLRNPYNIF-----DSIIVIISIWEIVGQADGGLSVLRTFRLLRVLKLVRFM---PALRRQLVVLMKTMDNVATFCMLLMLFIFIFSILGMHIFGCKF----------------SLRTDTGDTVPDRKNFDSLLWAIVTVFQILTQEDWNVVLYNGMAST----------TPWASLYFVALMTFGNYVLFNLLVAILVEGFQ 824 HSP 6 Score: 73.559 bits (179), Expect = 2.632e-11 Identity = 62/275 (22.55%), Postives = 127/275 (46.18%), Query Frame = 1 Query: 2167 KTLVNDVKFQRGILIAILINTLSMGIEYHQQPVQLTQT--LEFSNIVFSILFLIEMILKLIGEGIL----GYIKNGFNLFDGIIVVLGVIELCQQGGTSGLSILRTFRLLRILKL-------VRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKF----------------CTIENNKRTCDRKNFDSLLWSIVTVFQILTQEDWNTVLYNGM----------TRTSSWAALYFIALMTFGNYVLFNLLVAILVEGFSSER 2874 +T++ F +L I +N +++ +E Q T+ L SN +F+ +F+ EM LK++ G+ Y+++ +N+ DG +V + +I++ ++G + + + L + P L+ + +I ++ + + F IF ILG+ LF KF C N + + NFD+L +++++F + +++ W ++YNG+ T + W LYFI+ + ++ + N+ V ++VE F R Sbjct: 1123 QTIIAHKLFDYVVLAFIFLNCITIALERPQIEAGSTERIFLTVSNYIFTAIFVGEMTLKVVSLGLYFGEQAYLRSSWNVLDGFLVFVSIIDIVVSVASAGGAKILGVLRVLRLLRTLRPLRVISRAPGLKLVVETLISSLKPIGNIVLICCAFFIIFGILGVQLFKGKFYHCLGVDTRNITNRSDCVAANYRWVHHKYNFDNLGQALMSLFVLASKDGWVNIMYNGLDAVAVDQQPVTNHNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHKCR 1397 HSP 7 Score: 72.0182 bits (175), Expect = 6.865e-11 Identity = 59/173 (34.10%), Postives = 96/173 (55.49%), Query Frame = 1 Query: 3865 RQKCQHIVDKKSFDYLVLFFITLNCITLAMERP--SIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKG 4377 R C +V F+ + + I LNC+TL M +P + S L V + I F EM++K+++ G+ G + YL WN +D F+V +++ ++ L + N L R +R LRPL+ I+R P ++++V LL +L +GN++L+C F IFGI+GVQL+ G Sbjct: 67 RNWCIKMVCNPWFECVSMLVILLNCVTLGMYQPCDDMECLSDRCKILQVFDDFIFIFFAMEMVLKMVALGIF-GKKCYLGDTWNRLDFFIVMAGMVEY--SLDLQNIN-----LSAIRTVRVLRPLKAINRVPSMRILVNLLLDTLPMLGNVLLLCFFVFFIFGIIGVQLWAG 231 HSP 8 Score: 58.9214 bits (141), Expect = 7.366e-7 Identity = 68/220 (30.91%), Postives = 115/220 (52.27%), Query Frame = 1 Query: 4816 WRRT---INSVVTSKYFDLAIAGVIGLNVITMATEFHMMPQVLKTALKVFNYFFTSTFVXXXXXXXXXXXXXRYISDKWNQLDMMIVILSIAGVVIDEVESNFMPINPTIMRVMRVLRIARVLKLLKMASGIRALLDTVIQALPQVGNXXXXXXXXXXXXXXXXVELFG-----RLECSDINPCVGLGRHAHFENFGMAFLTLFRIATGDNWNGIMKDTL 5451 WR T + +V SKYF+ I I +N ++M E H P+ L L++ N FTS F LE +LKL A GL Y+ + +N D +IVI+SI ++ + + + V+R R+ RVLKL++ +R L +++ + V +L L +IF+ LG+ +FG R + D P +F++ A +T+F+I T ++WN ++ + + Sbjct: 584 WRETREKLRGIVDSKYFNRGIMMAILVNTVSMGIEHHEQPEELTNILEICNVVFTSMFALEMILKLAAFGLFDYLRNPYNIFDSIIVIISIW-EIVGQADGG--------LSVLRTFRLLRVLKLVRFMPALRRQLVVLMKTMDNVATFCMLLMLFIFIFSILGMHIFGCKFSLRTDTGDTVP-----DRKNFDSLLWAIVTVFQILTQEDWNVVLYNGM 789 HSP 9 Score: 56.9954 bits (136), Expect = 2.389e-6 Identity = 33/116 (28.45%), Postives = 60/116 (51.72%), Query Frame = 1 Query: 340 HIFHQNKHPRDWCLKIITWPWFEQLSMTIIAVNCITLSMYQPCGDQNCETSKCQIMQAFDYIIFAFFTCEMVIKIIAMG-FLGDLGYFGDTWNRLDMFIVIVGSIEILPSTGNNIG 684 ++F R C II F+ + + I +NCIT+++ +P +++ + +YI A F EM +K++++G + G+ Y +WN LD F+V V I+I+ S + G Sbjct: 1110 YLFSPENKFRILCQTIIAHKLFDYVVLAFIFLNCITIALERP--QIEAGSTERIFLTVSNYIFTAIFVGEMTLKVVSLGLYFGEQAYLRSSWNVLDGFLVFVSIIDIVVSVASAGG 1223
BLAST of Voltage-dependent T-type calcium channel subunit alpha vs. UniProt/SwissProt
Match: sp|Q9P0X4|CAC1I_HUMAN (Voltage-dependent T-type calcium channel subunit alpha-1I OS=Homo sapiens OX=9606 GN=CACNA1I PE=1 SV=1) HSP 1 Score: 637.106 bits (1642), Expect = 0.000e+0 Identity = 389/611 (63.67%), Postives = 487/611 (79.71%), Query Frame = 1 Query: 3832 SLYVFSVDNQFRQKCQHIVDKKSFDYLVLFFITLNCITLAMERPSIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKFYYCDGPHLQAVKTKNDCLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFHKCQENQXXXXXXXXXXXXXXXXXXXXXHLRAPLYWENYSKWRRTINSVVTSKYFDLAIAGVIGLNVITMATEFHMMPQVLKTALKVFNYFFTSTFVXXXXXXXXXXXXXRYISDKWNQLDMMIVILSIAGVVIDEVESN-FMPINPTIMRVMRVLRIARVLKLLKMASGIRALLDTVIQALPQVGNXXXXXXXXXXXXXXXXVELFGRLECSDINPCVGLGRHAHFENFGMAFLTLFRIATGDNWNGIMKDTLREKCISSEDCQRNCCVS-AIIAPIYFVIFXXXXXXXXXXXXXXXXXKHLEESHKMMCDDYELEREVQRDL 5658 S+Y+FS +N+FR CQ I+ K FDY+VL FI LNCIT+A+ERP I S ER+FLTV+NYIFT IF GEM +KV+S GL G+QAYL+S WN++DGFLVF+S++D+ +++ +I G+LRV RLLRTLRPLRVISRAPGLKLVV+TL+SSL+PIGNIVLICC FFIIFGILGVQLFKGKFY+C G + + ++DC+ + W + KYNFDNLGQALM+LFVL+SKDGWV IMY G+DAV V+ QP NHN W L+YFISFLL+V+FFVLNMFVGVVVENFHKC+++QE EE RR KR RRLEKKR+ + Y+ Y R I+S+ TS Y D+ I +I LNV+TM+ E + P L+TALK NY FT+ FVLEA+LKLVA GL R+ D+WNQLD+ IV+LS+ G+ ++E+E N +PINPTI+R+MRVLRIARVLKLLKMA+G+RALLDTV+QALPQVGNLGLLF LLF+I+AALGVELFG+L C+D NPC G+ RHA FENFGMAFLTLF+++TGDNWNGIMKDTLR+ C E R+C S ++P+YFV FVL AQFVL+NVVVAVLMKHL++S+K +D E++ E++ ++ Sbjct: 1149 SVYLFSPENRFRVLCQTIIAHKLFDYVVLAFIFLNCITIALERPQIEAGSTERIFLTVSNYIFTAIFVGEMTLKVVSLGLYFGEQAYLRSSWNVLDGFLVFVSIIDIVVSLASAGGAKILGVLRVLRLLRTLRPLRVISRAPGLKLVVETLISSLKPIGNIVLICCAFFIIFGILGVQLFKGKFYHCLGVDTRNITNRSDCMA-ANYRWVHHKYNFDNLGQALMSLFVLASKDGWVNIMYNGLDAVAVDQQPVTNHNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHKCRQHQEAEEARRREEKRLRRLEKKRRKAQRLPYYATYCHTRLLIHSMCTSHYLDIFITFIICLNVVTMSLEHYNQPTSLETALKYCNYMFTTVFVLEAVLKLVAFGLRRFFKDRWNQLDLAIVLLSVMGITLEEIEINAALPINPTIIRIMRVLRIARVLKLLKMATGMRALLDTVVQALPQVGNLGLLFMLLFFIYAALGVELFGKLVCNDENPCEGMSRHATFENFGMAFLTLFQVSTGDNWNGIMKDTLRD-CTHDE---RSCLSSLQFVSPLYFVSFVLTAQFVLINVVVAVLMKHLDDSNKEAQEDAEMDAELELEM 1754 HSP 2 Score: 357.451 bits (916), Expect = 5.233e-98 Identity = 239/494 (48.38%), Postives = 311/494 (62.96%), Query Frame = 1 Query: 286 PINPNESLIYHGFYATV-FHIFHQNKHPRDWCLKIITWPWFEQLSMTIIAVNCITLSMYQPCGDQNCETSKCQIMQAFDYIIFAFFTCEMVIKIIAMGFLGDLGYFGDTWNRLDMFIVIVGSIEILPSTGNNIGLTAIRTIRVLRPLRAINRIPSMRIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQMWQGVLRNRCYLNLNESFRHPGLNLSSFYQINRTLFLNAVDKDFICSTDKNNGILKCSDIPPSIMLLSNNSLQIC--KQPARPFT---DNLPTKHSCVNWNQYYTDCQPGEKNPYEGAINFDNIGFAWVAIFQVISMESWVDIMYYVQDAHSFWDWIYFVALIIIGSFFMINLCLVVIASQFSETKRRETERMWIERRRFNSSNCSSISKDEPQTCYLEXXXXXXXXXXXXYRRIVKLYNQIQIR----------------HSKTAQGNYQNKLKRQ--------RKHCNVCLNSRSQFPIDDH 1677 P++ + + H A + F Q PR+WC+K++ PWFE +SM +I +NC+TL MYQPC D +C + +C+I+Q FD IF FF EMV+K++A+G G Y GDTWNRLD FIV+ G +E NI L+AIRT+RVLRPL+AINR+PSMRILV LLLDTLPMLGNVLLLCFFVFFIFGIIGVQ+W G+LRNRC+L N + + + L +YQ + FICS +NGI+ C +IPP L + C K F +L CVNWN+YY C+ G NP++GAINFDNIG+AW+ IFQVI++E WV+IMYYV DAHSF+++IYF+ LII+GSFFMINLCLVVIA+QFSETK+RE M +R+R+ SS+ + S EP CY EI + + I+ K RR + LY +Q R H+K + +Y K K Q +HC S P +DH Sbjct: 41 PLDGADPHVPHPDLAPIAFFCLRQTTSPRNWCIKMVCNPWFECVSMLVILLNCVTLGMYQPCDDMDCLSDRCKILQVFDDFIFIFFAMEMVLKMVALGIFGKKCYLGDTWNRLDFFIVMAGMVEYSLDL-QNINLSAIRTVRVLRPLKAINRVPSMRILVNLLLDTLPMLGNVLLLCFFVFFIFGIIGVQLWAGLLRNRCFLEENFTIQG-DVALPPYYQPEED-----DEMPFICSLSGDNGIMGCHEIPP----LKEQGRECCLSKDDVYDFGAGRQDLNASGLCVNWNRYYNVCRTGSANPHKGAINFDNIGYAWIVIFQVITLEGWVEIMYYVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQREHRLMLEQRQRYLSSS-TVASYAEPGDCYEEIFQYVCHILRKAKRRALGLYQALQSRRQALGPEAPAPAKPGPHAKEPR-HYHGKTKGQGDEGRHLGSRHCQTLHGPAS--PGNDH 519 HSP 3 Score: 272.707 bits (696), Expect = 6.124e-72 Identity = 155/240 (64.58%), Postives = 194/240 (80.83%), Query Frame = 1 Query: 2155 QQKIKTLVNDVKFQRGILIAILINTLSMGIEYHQQPVQLTQTLEFSNIVFSILFLIEMILKLIGEGILGYIKNGFNLFDGIIVVLGVIELCQQGGTSGLSILRTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKFCTIENNKRTC-DRKNFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTSSWAALYFIALMTFGNYVLFNLLVAILVEGFSSE 2871 + K++ +V+ F RGI++AIL+NT+SMGIE+H+QP +LT LE N+VF+ +F +EMILKL G+ Y++N +N+FD IIV++ + E+ Q GLS+LRTFRLLR+LKLVRFMPALR+QL V+++T+DNVATF LL+LFIFIFSILGM +FGCKF + T DRKNFDSLLW+IVTVFQILTQEDWN VLYNGM TS WA+LYF+ALMTFGNYVLFNLLVAILVEGF +E Sbjct: 630 RAKLRGIVDSKYFNRGIMMAILVNTVSMGIEHHEQPEELTNILEICNVVFTSMFALEMILKLAAFGLFDYLRNPYNIFDSIIVIISIWEIVGQA-DGGLSVLRTFRLLRVLKLVRFMPALRRQLVVLMKTMDNVATFCMLLMLFIFIFSILGMHIFGCKFSLRTDTGDTVPDRKNFDSLLWAIVTVFQILTQEDWNVVLYNGMASTSPWASLYFVALMTFGNYVLFNLLVAILVEGFQAE 868 HSP 4 Score: 96.2857 bits (238), Expect = 3.272e-18 Identity = 64/250 (25.60%), Postives = 128/250 (51.20%), Query Frame = 1 Query: 2203 ILIAILINTLSMGIEYHQQPVQLTQTLEFSNIVFSILFLIEMILKLIGEGILGYIKNGFNLFDGIIVVLGVIELCQQG---------GTSGLSILRTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKFCTIENNKRTCDR-KNFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTSS-----------WAALYFIALMTFGNYVLFNLLVAILVEGFSSERLDEQK 2889 I I +N ++M +E++ QP L L++ N +F+ +F++E +LKL+ G+ + K+ +N D IV+L V+ + + + + I+R R+ R+LKL++ +R L +++ + V L +L FI++ LG+ LFG C EN R F++ + +T+FQ+ T ++WN ++ + + + + LYF++ + +VL N++VA+L++ + Q+ Sbjct: 1493 ITFIICLNVVTMSLEHYNQPTSLETALKYCNYMFTTVFVLEAVLKLVAFGLRRFFKDRWNQLDLAIVLLSVMGITLEEIEINAALPINPTIIRIMRVLRIARVLKLLKMATGMRALLDTVVQALPQVGNLGLLFMLLFFIYAALGVELFGKLVCNDENPCEGMSRHATFENFGMAFLTLFQVSTGDNWNGIMKDTLRDCTHDERSCLSSLQFVSPLYFVSFVLTAQFVLINVVVAVLMKHLDDSNKEAQE 1742 HSP 5 Score: 93.5893 bits (231), Expect = 2.322e-17 Identity = 70/279 (25.09%), Postives = 134/279 (48.03%), Query Frame = 1 Query: 3865 RQKCQHIVDKKSFDYLVLFFITLNCITLAMERPSIPPHSKERL--FLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKFYYCDGPHLQAVKTKNDCLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFH 4695 R K + IVD K F+ ++ I +N +++ +E P E L L + N +FT +F EMI+K+ + GL YL++ +NI ++ + I ++G ++ +LR FRLLR L+ +R + P L+ + L+ ++ + ++ F IF ILG+ +F KF L+ + + NFD+L A++ +F + +++ W ++Y G+ + + WA +YF++ + + + N+ V ++VE F Sbjct: 630 RAKLRGIVDSKYFNRGIMMAILVNTVSMGIEHHEQP----EELTNILEICNVVFTSMFALEMILKLAAFGLF----DYLRNPYNIF-----DSIIVIISIWEIVGQADGGLSVLRTFRLLRVLKLVRFM---PALRRQLVVLMKTMDNVATFCMLLMLFIFIFSILGMHIFGCKF----------------SLRTDTGDTVPDRKNFDSLLWAIVTVFQILTQEDWNVVLYNGMAST----------SPWASLYFVALMTFGNYVLFNLLVAILVEGFQ 866 HSP 6 Score: 73.1738 bits (178), Expect = 2.892e-11 Identity = 62/275 (22.55%), Postives = 127/275 (46.18%), Query Frame = 1 Query: 2167 KTLVNDVKFQRGILIAILINTLSMGIEYHQQPVQLTQT--LEFSNIVFSILFLIEMILKLIGEGIL----GYIKNGFNLFDGIIVVLGVIELCQQGGTSGLSILRTFRLLRILKL-------VRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKF----------------CTIENNKRTCDRKNFDSLLWSIVTVFQILTQEDWNTVLYNGM----------TRTSSWAALYFIALMTFGNYVLFNLLVAILVEGFSSER 2874 +T++ F +L I +N +++ +E Q T+ L SN +F+ +F+ EM LK++ G+ Y+++ +N+ DG +V + +I++ ++G + + + L + P L+ + +I ++ + + F IF ILG+ LF KF C N + + NFD+L +++++F + +++ W ++YNG+ T + W LYFI+ + ++ + N+ V ++VE F R Sbjct: 1164 QTIIAHKLFDYVVLAFIFLNCITIALERPQIEAGSTERIFLTVSNYIFTAIFVGEMTLKVVSLGLYFGEQAYLRSSWNVLDGFLVFVSIIDIVVSLASAGGAKILGVLRVLRLLRTLRPLRVISRAPGLKLVVETLISSLKPIGNIVLICCAFFIIFGILGVQLFKGKFYHCLGVDTRNITNRSDCMAANYRWVHHKYNFDNLGQALMSLFVLASKDGWVNIMYNGLDAVAVDQQPVTNHNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHKCR 1438 HSP 7 Score: 72.0182 bits (175), Expect = 6.537e-11 Identity = 59/173 (34.10%), Postives = 96/173 (55.49%), Query Frame = 1 Query: 3865 RQKCQHIVDKKSFDYLVLFFITLNCITLAMERP--SIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKG 4377 R C +V F+ + + I LNC+TL M +P + S L V + I F EM++K+++ G+ G + YL WN +D F+V +++ ++ L + N L R +R LRPL+ I+R P ++++V LL +L +GN++L+C F IFGI+GVQL+ G Sbjct: 69 RNWCIKMVCNPWFECVSMLVILLNCVTLGMYQPCDDMDCLSDRCKILQVFDDFIFIFFAMEMVLKMVALGIF-GKKCYLGDTWNRLDFFIVMAGMVEY--SLDLQNIN-----LSAIRTVRVLRPLKAINRVPSMRILVNLLLDTLPMLGNVLLLCFFVFFIFGIIGVQLWAG 233 HSP 8 Score: 59.3066 bits (142), Expect = 5.095e-7 Identity = 69/226 (30.53%), Postives = 116/226 (51.33%), Query Frame = 1 Query: 4798 WENYSKWRRT---INSVVTSKYFDLAIAGVIGLNVITMATEFHMMPQVLKTALKVFNYFFTSTFVXXXXXXXXXXXXXRYISDKWNQLDMMIVILSIAGVVIDEVESNFMPINPTIMRVMRVLRIARVLKLLKMASGIRALLDTVIQALPQVGNXXXXXXXXXXXXXXXXVELFG-----RLECSDINPCVGLGRHAHFENFGMAFLTLFRIATGDNWNGIMKDTL 5451 W WR T + +V SKYF+ I I +N ++M E H P+ L L++ N FTS F LE +LKL A GL Y+ + +N D +IVI+SI ++ + + + V+R R+ RVLKL++ +R L +++ + V +L L +IF+ LG+ +FG R + D P +F++ A +T+F+I T ++WN ++ + + Sbjct: 620 WLCGDVWRETRAKLRGIVDSKYFNRGIMMAILVNTVSMGIEHHEQPEELTNILEICNVVFTSMFALEMILKLAAFGLFDYLRNPYNIFDSIIVIISIW-EIVGQADGG--------LSVLRTFRLLRVLKLVRFMPALRRQLVVLMKTMDNVATFCMLLMLFIFIFSILGMHIFGCKFSLRTDTGDTVP-----DRKNFDSLLWAIVTVFQILTQEDWNVVLYNGM 831 HSP 9 Score: 56.9954 bits (136), Expect = 2.602e-6 Identity = 33/116 (28.45%), Postives = 60/116 (51.72%), Query Frame = 1 Query: 340 HIFHQNKHPRDWCLKIITWPWFEQLSMTIIAVNCITLSMYQPCGDQNCETSKCQIMQAFDYIIFAFFTCEMVIKIIAMG-FLGDLGYFGDTWNRLDMFIVIVGSIEILPSTGNNIG 684 ++F R C II F+ + + I +NCIT+++ +P +++ + +YI A F EM +K++++G + G+ Y +WN LD F+V V I+I+ S + G Sbjct: 1151 YLFSPENRFRVLCQTIIAHKLFDYVVLAFIFLNCITIALERP--QIEAGSTERIFLTVSNYIFTAIFVGEMTLKVVSLGLYFGEQAYLRSSWNVLDGFLVFVSIIDIVVSLASAGG 1264 HSP 10 Score: 55.4546 bits (132), Expect = 6.898e-6 Identity = 28/95 (29.47%), Postives = 51/95 (53.68%), Query Frame = 1 Query: 1150 TDCQPGEKNPYEGAINFDNIGFAWVAIFQVISMESWVDIMYYVQDA----------HSFWDWIYFVALIIIGSFFMINLCLVVIASQFSETKRRE 1404 +DC NFDN+G A +++F + S + WV+IMY DA H+ W +YF++ ++I SFF++N+ + V+ F + ++ + Sbjct: 1347 SDCMAANYRWVHHKYNFDNLGQALMSLFVLASKDGWVNIMYNGLDAVAVDQQPVTNHNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHKCRQHQ 1441
BLAST of Voltage-dependent T-type calcium channel subunit alpha vs. TrEMBL
Match: G0YP35 (Voltage operated calcium channel Cav3 (Fragment) OS=Dugesia japonica OX=6161 PE=2 SV=1) HSP 1 Score: 1668.67 bits (4320), Expect = 0.000e+0 Identity = 916/1096 (83.58%), Postives = 1001/1096 (91.33%), Query Frame = 1 Query: 2905 RQSLKKRRANNKQLRIMQHQSENLVLLTNSIQKDQTGENQKISSQPPVIIHTAATPMPTPRSSPYNELVXXXXXXXXXXXXXXXQSILSINKSFETTSSRNINTTILQEDASIMPGMKNSKQNLDSTLFVEHHIPVQKTPTSNGLNVKLVSIPIPYTTN---RSNFIIP--SSILLRQGSINSFMGSVNSDRSKILLDEKKSISETDEKSLSRQSSFKSFMAYKNKINQLTIPFSNRYSLSLDSEGKSNYQFKMNYLLAREKALEEPDDSNSESQNSSRMNNVEDPDEEDMEAMICLSKCCPQPKGIFAKRYYHSLYVFSVDNQFRQKCQHIVDKKSFDYLVLFFITLNCITLAMERPSIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKFYYCDGPHLQAVKTKNDCLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFHKCQENQXXXXXXXXXXXXXXXXXXXXXHLRAPLYWENYSKWRRTINSVVTSKYFDLAIAGVIGLNVITMATEFHMMPQVLKTALKVFNYFFTSTFVXXXXXXXXXXXXXRYISDKWNQLDMMIVILSIAGVVIDEVESNFMPINPTIMRVMRVLRIARVLKLLKMASGIRALLDTVIQALPQVGNXXXXXXXXXXXXXXXXVELFGRLECSDINPCVGLGRHAHFENFGMAFLTLFRIATGDNWNGIMKDTLREKCISSEDCQRNCCVSAIIAPIYFVIFXXXXXXXXXXXXXXXXXKHLEESHKMMCDDYELEREVQRDLDEEAKELAREKQLKDEENNENTLIDIEIDKNNNFLDKKENNSINQNQIKKLSCGDCHSINAQLRNVSCQNVHLVNIYSKNLSRSHPHLFVNLDSASFXXXXXXXXXXXXXQRRLSMKKESWNNESVMFNNNKPMKISENPKSLKSKINKSQQSTTELRLSEKRKLFAKSKINE 6177 RQSLKKR+AN KQ R+MQ+ ++NL+ L+N+ QKD +Q+IS+QPP+IIHTAATPMPTPRSSPYNE VTT +N+ QSILSINKSFETTSSRNINTT + ++ +P + N K N+D++ E I V K SNGLNVKLVSIPIPY N +SNFIIP SSILLRQGSINSFMGS+NS++S+I+ DEKKS+SE DEKS+SRQSSFKSFMAYKNKINQLTIP +NRYSLSLDS+GKSNYQFKM YLL REKALEEPDD+NSESQNSSR+NNVED D+ED+EAM+CLSKCCPQPKGIFAKRYYHS+Y+FSVDNQFRQKCQ+ VDKK FDYLVLFFITLNCITLAMERPSIPP SKERLFL+VTNYIFTIIFTGEMI+KVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITI LGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKFYYCDGPHL V TKNDC+ + +NEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAV V++QPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFHKCQENQEKEEKARRAAKRARRLEKKRKHLRAPLYWENYSKWRRTIN+VVTSKYFDLAIAGVIGLNVITMATEFHMMP VLKTALKVFNYFFT+TFVLEA+LKLVALGL RYISDKWNQLDM+IVILSIAGVV+DEVE+NFMPINPTIMRVMRVLRIARVLKLLKMASGIRALLDTVIQALPQVGNLGLLFFLLFYIFAALGVELFGRLECS++NPCVGLGRHAHFENFGMAFLTLFRIATGDNWNGIMKDTLR+KC SSEDCQRNCCVSAIIAPIYFVIFVLMAQFVLVNVVVAVLMKHLEESHKMMCDDYELEREVQRDLDEEAKE AREKQLK+EENNEN LI+IE DKNNN ++KKEN S+ + Q+KKLSC DC+SIN +L+N+SCQNVHL+NI SKNLS+SHPHLFVN DS+SFT N +T N+NK +QRRLSMKK+ NN+++M NNNK ++ EN K KIN +QQS+ EL L+EKRKLF ++KI+E Sbjct: 1 RQSLKKRQANLKQNRLMQNHTDNLLFLSNANQKDIN--DQRISTQPPLIIHTAATPMPTPRSSPYNEFVTTTIPITNQSNS---QSILSINKSFETTSSRNINTTTISDNPQTIPNISNKKTNIDNSAVFEPQIHVPKNIISNGLNVKLVSIPIPYNNNNNNKSNFIIPPRSSILLRQGSINSFMGSINSEKSRII-DEKKSVSELDEKSISRQSSFKSFMAYKNKINQLTIPCTNRYSLSLDSDGKSNYQFKMGYLLTREKALEEPDDTNSESQNSSRINNVEDQDDEDIEAMVCLSKCCPQPKGIFAKRYYHSMYIFSVDNQFRQKCQYFVDKKWFDYLVLFFITLNCITLAMERPSIPPQSKERLFLSVTNYIFTIIFTGEMIVKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITISLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKFYYCDGPHLLNVTTKNDCIAHERNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVSVDVQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFHKCQENQEKEEKARRAAKRARRLEKKRKHLRAPLYWENYSKWRRTINAVVTSKYFDLAIAGVIGLNVITMATEFHMMPHVLKTALKVFNYFFTTTFVLEAILKLVALGLTRYISDKWNQLDMIIVILSIAGVVVDEVENNFMPINPTIMRVMRVLRIARVLKLLKMASGIRALLDTVIQALPQVGNLGLLFFLLFYIFAALGVELFGRLECSELNPCVGLGRHAHFENFGMAFLTLFRIATGDNWNGIMKDTLRDKCTSSEDCQRNCCVSAIIAPIYFVIFVLMAQFVLVNVVVAVLMKHLEESHKMMCDDYELEREVQRDLDEEAKEQAREKQLKEEENNENLLINIEKDKNNNCVEKKENESVKKPQMKKLSCDDCYSINEKLKNISCQNVHLINICSKNLSKSHPHLFVNFDSSSFTRNIQTNNINKFIQRRLSMKKDRLNNDTLMLNNNKQIRNIENQWHQKCKINNNQQSSMELTLAEKRKLFTRNKIHE 1090 HSP 2 Score: 81.6481 bits (200), Expect = 2.166e-11 Identity = 84/314 (26.75%), Postives = 153/314 (48.73%), Query Frame = 1 Query: 2155 QQKIKTLVNDVKFQRGILIAILINTLSMGIEYHQQPVQLTQTLEFSNIVFSILFLIEMILKLIGEGILGYIKNGFNLFDGIIVVLGVIELCQQG--------GTSGLSILRTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKFCTIENNKRTCDR-KNFDSLLWSIVTVFQILTQEDWNTVLYNGMTR--TSS------------WAALYFIALMTFGNYVLFNLLVAILVEGFSSER---LDEQKLLHNYRQSL---KKRRANNKQLRIMQHQSENLVLLTNSIQKDQ 3009 ++ I +V F I I +N ++M E+H P L L+ N F+ F++E ILKL+ G+ YI + +N D IIV+L + + + + ++R R+ R+LKL++ +R L +I+ + V L L +IF+ LG+ LFG C+ N R +F++ + +T+F+I T ++WN ++ + + TSS A +YF+ + +VL N++VA+L++ D+ +L ++ L K +A KQL+ + +ENL++ +I+KD+ Sbjct: 638 RRTINAVVTSKYFDLAIAGVIGLNVITMATEFHMMPHVLKTALKVFNYFFTTTFVLEAILKLVALGLTRYISDKWNQLDMIIVILSIAGVVVDEVENNFMPINPTIMRVMRVLRIARVLKLLKMASGIRALLDTVIQALPQVGNLGLLFFLLFYIFAALGVELFGRLECSELNPCVGLGRHAHFENFGMAFLTLFRIATGDNWNGIMKDTLRDKCTSSEDCQRNCCVSAIIAPIYFVIFVLMAQFVLVNVVVAVLMKHLEESHKMMCDDYELEREVQRDLDEEAKEQAREKQLK-EEENNENLLI---NIEKDK 947 HSP 3 Score: 79.337 bits (194), Expect = 9.670e-11 Identity = 75/283 (26.50%), Postives = 134/283 (47.35%), Query Frame = 1 Query: 2155 QQKIKTLVNDVKFQRGILIAILINTLSMGIEYHQQPVQLTQTLEFS--NIVFSILFLIEMILKLIGEGIL----GYIKNGFNLFDGIIVVLGVIEL--CQQGGTSGLSILRTFRLLRILK---------LVRFMPALR---QQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKF----------------CTI-ENNKRTCDRKNFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTS----------SWAALYFIALMTFGNYVLFNLLVAILVEGF 2862 +QK + V+ F +L I +N +++ +E P Q + L S N +F+I+F EMI+K++ +G+L Y+K+G+N+ DG +V + +++L G S R F +LR+ + ++ P L+ Q L +R I N+ + F IF ILG+ LF KF C E N+ + NFD+L +++ +F + +++ W ++Y G+ S WA +YFI+ + + + N+ V ++VE F Sbjct: 320 RQKCQYFVDKKWFDYLVLFFITLNCITLAMERPSIPPQSKERLFLSVTNYIFTIIFTGEMIVKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITISLGHSN----RIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIV---LICCTFFIIFGILGVQLFKGKFYYCDGPHLLNVTTKNDCIAHERNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVSVDVQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENF 595 HSP 4 Score: 65.0846 bits (157), Expect = 2.531e-6 Identity = 35/123 (28.46%), Postives = 60/123 (48.78%), Query Frame = 1 Query: 295 PNESLIYHGFYATVFHIFHQNKHPRDWCLKIITWPWFEQLSMTIIAVNCITLSMYQPCGDQNCETSKCQIMQAFDYIIFAFFTCEMVIKIIAMGFL-GDLGYFGDTWNRLDMFIVIVGSIEIL 660 P I+ Y +IF + R C + WF+ L + I +NCITL+M +P ++ + + +YI FT EM++K+++ G L GD Y WN +D F+V + +++ Sbjct: 296 PQPKGIFAKRYYHSMYIFSVDNQFRQKCQYFVDKKWFDYLVLFFITLNCITLAMERPSIPP--QSKERLFLSVTNYIFTIIFTGEMIVKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLF 416
BLAST of Voltage-dependent T-type calcium channel subunit alpha vs. TrEMBL
Match: X1WBF7 (Voltage-dependent T-type calcium channel subunit alpha OS=Danio rerio OX=7955 GN=cacna1ha PE=3 SV=1) HSP 1 Score: 1286.94 bits (3329), Expect = 0.000e+0 Identity = 874/1848 (47.29%), Postives = 1160/1848 (62.77%), Query Frame = 1 Query: 418 MTIIAVNCITLSMYQPCGDQNCETSKCQIMQAFDYIIFAFFTCEMVIKIIAMGFLGDLGYFGDTWNRLDMFIVIVGSIEILPSTGNNIGLTAIRTIRVLRPLRAINRIPSMRIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQMWQGVLRNRCYLNLNESFRHPGLNLSSFYQINRTLFLNAVDKDFICSTDKNNGILKCSDIPP---SIMLLSNNSLQICKQPARPFTDNLPTKHSCVNWNQYYTDCQPGEKNPYEGAINFDNIGFAWVAIFQVISMESWVDIMYYVQDAHSFWDWIYFVALIIIGSFFMINLCLVVIASQFSETKRRETERMWIERRRFNSSNCSSISKDEPQTCYLEXXXXXXXXXXXXYRRIVKLYNQIQIRHSKT------------------AQGNYQNKL-----KRQRKHCNVCLNSRSQFPI-----DDHCHLYSI--------------VNTISGDKQHYYAINKYPINFSNIPPKASPELSVIDVL-------NSPRHPNHLISDISSKSVSTETKRKSQYN---------------------------------SQILLEIPSTPANHSTTRDNYRWELTNNPLLTSKDKVYPQSVASRSSSINSCAYQIPRLTDSYSKHRRPFNKNQNKTKRKNYLSICQQKIKTLVNDVKFQRGILIAILINTLSMGIEYHQQPVQLTQTLEFSNIVFSILFLIEMILKLIGEGILGYIKNGFNLFDGIIVVLGVIELCQQGGTSGLSILRTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKFC-TIENNKRTCDRKNFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTSSWAALYFIALMTFGNYVLFNLLVAILVEGFSSERLDEQKLLHNYRQSLKKRRANNKQLRIMQHQSENLVLLTNSIQKDQTGENQKISSQPPVIIHTAATPMPTPRSSPYNELVXXXXXXXXXXXXXXXQSILSINKSFETTSSRNINTTILQEDASIMPGMKNSKQNLDSTLFVEHHIPVQKTPTSNGLNVKLVSIPIPYTTNRSNFIIPSSILLRQGSINSFMGSVNSDRSKILLDEKKSISETDEKSLSRQSSFKSFMAYKNKINQLTIPFSNRYSLSLDSEGKSNYQFKMNYLLAREKALEEPDDSNSESQNSSRMNNVEDPDEEDMEAMIC--LSKCCPQPKGIFAKRYYH-SLYVFSVDNQFRQKCQHIVDKKSFDYLVLFFITLNCITLAMERPSIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKFYYCDGPHLQAVKTKNDCLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFHKCQENQXXXXXXXXXXXXXXXXXXXXXH-LRAPLYWENYSKWRRTINSVVTSKYFDLAIAGVIGLNVITMATEFHMMPQVLKTALKVFNYFFTSTFVXXXXXXXXXXXXXRYISDKWNQLDMMIVILSIAGVVIDEVESN-FMPINPTIMRVMRVLRIARVLKLLKMASGIRALLDTVIQALPQVGNXXXXXXXXXXXXXXXXVELFGRLECSDINPCVGLGRHAHFENFGMAFLTLFRIATGDNWNGIMKDTLREKCISSEDCQRNCCVSAI--IAPIYFVIFXXXXXXXXXXXXXXXXXKHLEESHKMMCDDYELEREVQRDLDEEAKELA 5682 M +I +NC+TL MYQPC D C++ C ++QAFD IFAFF EMVIK+IA+G G GY GDTWNRLD FIV+ G +E G+N L+AIRT+RVLRPLRAINR+PSMRILV LLLDTLPMLGNVLLLCFFVFFIFGI+GVQ+W G+LRNRC++ ++ L+ S Y N + D FICS+ K+NG+ +CS +PP + N S T N +SCVNWNQYY++C+PG+ NP++GA+NFDNIG+AW+AIFQVI++E WVDIMYYV DAHSF+++IYF+ LII+GSFFMINLCLVVIA+QF+ETK+RE M +R R+ S++ + S EP +CY E++K ++ + K+ RR+ ++YN Q + K G++ + + QR+HC+ L++ S P+ + + SI + +S Q ++I Y +F P + +P + L N P LI + S + + KS N +Q+LLE+ S P Y + L D YP+ S + +Y +T + H+ + QN+ + + ++++ +V+ F RGI+IAILINTLSMGIEYH+QP +LT LE SNIVF+ +F++EM+ KL+ GI GYI+N +N+FDG+IVV+ V E+ GLS+LRTFRLLR+LKLVRF+PALR+QL V+++T+DNVATF LL+LFIF FSILGM LFGCKF +EN DRKNFDSLLW+IVTVFQILTQEDWN VLYNGM TS WAALYF+ALMTFGNYVLFNLLVAILVEGF +E D K +++ + N + ++ Q QS + + D G + PP+I+ TAATPMPTP+SS L F+ T SR + + +A + + +++ P P +G N + + RS++ + L R S+ + +R +L E + E D+ + ++ + L IP + LD G+S ++LA A +DS + EED++ C L + K + K + SLY+FS N+FR CQ ++ K FDY+VL FI LNCIT+A+ERP I ERLFL V+NY+FT+IF EM +KV++ G G+Q+YLKS WN++DG LVF+SL+D+ ++ L NRIFGILRV RLLRTLRPLRVISRAPGLKLVV+TL++SLRPIGNIVLICC FFI+FGILGVQLFKGKF++C+G + + K+DCL+ + +W +KYNFDNLGQALM+LFVLS KDGWV IMY G+DAVGV+ QP+ NHN W L+YFISFLL+V+FFVLNMFVGVVVENFHKC+++QE+ E KR + +EKKR+ LR P Y+ +YS R I+++ T+ Y DL I G+I +NV+TM+ E P L ALK NY FT F++EALLKLVA G+ R+ D+WNQLD+ IV+LSI G+ ++E++ N +PINPTI+R+MRVLRIARVLKLLKMA+G+R+LLDTV+QALPQVGNLGLLF LLF+I+AALGVELFG+LEC++ NPC GL HA FENFGMAFLTLFR++TGDNWNGIMKDTLRE C+ SE C+S + ++PIYFV FVLMAQFVLVNVVVAVLMKHLEES+K +D E++ ++ + +E + L+ Sbjct: 1 MLVILLNCVTLGMYQPCEDLKCQSEWCIVLQAFDDCIFAFFAVEMVIKMIALGIFGINGYLGDTWNRLDFFIVMAGMME-YSLDGHNASLSAIRTVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAGLLRNRCFMPSKVRDQY-NLSYMSLYYENE----DGEDNPFICSSSKDNGMKRCSAVPPLKEGVECTLNASFLGHVYSGLSGTGN----YSCVNWNQYYSECKPGDLNPHKGAVNFDNIGYAWIAIFQVITLEGWVDIMYYVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIATQFAETKQRENMLMKEQRARYRSNDSTLASYSEPGSCYEEMLKYVSHLYRKVKRRLSRIYNSWQSKRRKKVNPNTGAGGGANGHSRHRGYGHWVQSIHSLIQQHQRQHCH--LSNGSPSPVATTGSSEALEMRSITAGQQLTVSSQPTATHNLSSSTQSVHSI--YQGDFREAPQERTPTNVAVPALSRLNGGMNYPTILPSLICNYSGGGSLGKERGKSDANTGHEVIQDFDKLHQQIEAHSHSRVLLQMAGVVPTQLLLEVMSCP---------YCVRALESMDLEIGDSDYPR---SEGDMVYEFSYDAGFITGRSAHHK--MQEKQNRLVQ--FWEDFRERLTRIVDSKYFNRGIMIAILINTLSMGIEYHEQPEELTNILEISNIVFTSMFVLEMLFKLLAFGIFGYIRNPYNIFDGVIVVISVWEIIGH-ADGGLSVLRTFRLLRVLKLVRFLPALRRQLLVLMKTMDNVATFCMLLMLFIFTFSILGMHLFGCKFSLKMENGDTIPDRKNFDSLLWAIVTVFQILTQEDWNVVLYNGMASTSPWAALYFVALMTFGNYVLFNLLVAILVEGFQAEG-DANK-----SDGDEEKTSVNSEEKMEQLQS------SANGHVDPCG-----TLPPPIIMRTAATPMPTPKSS------------------------LGPESVFDLTESRRGSAVSIDPNAFDQKSLSSPRRS-----------PCH--PRGSGSN---------WGSRRSSW----NSLGRAPSLKR--KDTSGERESLLSGEGRGSFEDDDIEAEKLTNISG--GSLQHPSSLDIPELPQMGEYLDCNGRS------QHILADLSASLNKEDSIA---------------EEDLDDSFCFRLRRTLAAYKPKWCKDHEEWSLYLFSPHNKFRMMCQKLISHKMFDYVVLVFIFLNCITIALERPHI--QQSERLFLLVSNYVFTVIFVAEMTVKVVALGFYSGNQSYLKSTWNVLDGVLVFVSLIDILVS-LAWTGNRIFGILRVLRLLRTLRPLRVISRAPGLKLVVETLITSLRPIGNIVLICCAFFIVFGILGVQLFKGKFFHCEGGDTRNITNKSDCLQ-ANLKWIRRKYNFDNLGQALMSLFVLSCKDGWVNIMYDGLDAVGVDQQPERNHNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHKCRQDQEEVEARLLELKRQKLMEKKRRKALRRP-YYADYSPARLYIHTLCTNHYLDLFITGIICINVVTMSIEHFNQPSYLDEALKYCNYVFTIIFIIEALLKLVAFGIRRFFKDRWNQLDLAIVLLSIMGITLEEIKMNAALPINPTIIRIMRVLRIARVLKLLKMATGMRSLLDTVMQALPQVGNLGLLFMLLFFIYAALGVELFGKLECTENNPCEGLSPHATFENFGMAFLTLFRVSTGDNWNGIMKDTLRE-CLPSE----TQCLSYLPWVSPIYFVTFVLMAQFVLVNVVVAVLMKHLEESNKEAKEDAEMDAAIKLAILKETRRLS 1715 HSP 2 Score: 63.5438 bits (153), Expect = 7.943e-6 Identity = 38/119 (31.93%), Postives = 64/119 (53.78%), Query Frame = 1 Query: 337 FHIFHQNKHPRDWCLKIITWPWFEQLSMTIIAVNCITLSMYQPCGDQNCETSKCQIMQAFDYIIFAFFTCEMVIKIIAMGFL-GDLGYFGDTWNRLDMFIVIVGSIEILPS---TGNNI 681 ++F + R C K+I+ F+ + + I +NCIT+++ +P + + S+ + +Y+ F EM +K++A+GF G+ Y TWN LD +V V I+IL S TGN I Sbjct: 1106 LYLFSPHNKFRMMCQKLISHKMFDYVVLVFIFLNCITIALERP----HIQQSERLFLLVSNYVFTVIFVAEMTVKVVALGFYSGNQSYLKSTWNVLDGVLVFVSLIDILVSLAWTGNRI 1220
BLAST of Voltage-dependent T-type calcium channel subunit alpha vs. TrEMBL
Match: A0A2C9KE73 (Uncharacterized protein OS=Biomphalaria glabrata OX=6526 GN=106079304 PE=3 SV=1) HSP 1 Score: 1135.17 bits (2935), Expect = 0.000e+0 Identity = 699/1278 (54.69%), Postives = 869/1278 (68.00%), Query Frame = 1 Query: 2155 QQKIKTLVNDVKFQRGILIAILINTLSMGIEYHQQPVQLTQTLEFSNIVFSILFLIEMILKLIGEGILGYIKNGFNLFDGIIVVLGVIELCQQG--GTSGLSILRTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKFCT-IENNKRTCDRKNFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTSSWAALYFIALMTFGNYVLFNLLVAILVEGFSS----------------------------ERLDEQKLLHNYRQSLKKRRANNKQLRIMQHQSENLVLLTNS----IQKDQTGENQKISSQ-----PPVIIHTAATPMPTPRSSP-YNELVXXXXXXXXXXXXXXXQSILSINK----SFETTSSR--------NINTTILQEDAS---------------IMPGMKNSKQNLDSTLFVEHHIPVQKTPTSNGLNVKLVSI-----PIPYTTNRSNFIIP---SSILLRQGSI--------NSFMGSVNSDRSKILLDEKKSISETDEKSLSRQSSFKSFMAYKNKINQLTIPFSNRYSLSLDSEGKSNYQFKMNYLLAREKALEEPDDSNSESQNSSRMNNVEDPDEEDMEAMICLSKCCPQPKGIFAKRYYHSLYVFSVDNQFRQKCQHIVDKKSFDYLVLFFITLNCITLAMERPSIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKFYYCDGPHLQAVKTKNDCLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFHKCQENQXXXXXXXXXX--------XXXXXXXXXXXHLRAPLYWENYSKWRRTINSVVTSKYFDLAIAGVIGLNVITMATEFHMMPQVLKTALKVFNYFFTSTFVXXXXXXXXXXXXXRYISDKWNQLDMMIVILSIAGVVIDEVESNFMPINPTIMRVMRVLRIARVLKLLKMASGIRALLDTVIQALPQVGNXXXXXXXXXXXXXXXXVELFGRLECSDINPCVGLGRHAHFENFGMAFLTLFRIATGDNWNGIMKDTLREKCISSEDCQRNCCVSAIIAPIYFVIFXXXXXXXXXXXXXXXXXKHLEESHKMMCDDYELEREVQRDLDEEAKELAREKQLKDEEN 5712 Q+++K V FQR IL+AIL+NTLSMG+EYH QP +LT LE+SNIVF ++F EM K+ G+ GYI NGFN+FDG IV+L ++EL Q G G SGLS+LRTFRLLRILKLVRFMPALR+QL VM+RT+DNVATFFALL+LF+FIFSILGM+LFGCKFC +E+ R CDRKNFDSLLW+I+TVFQ+LTQEDWNTVLYNGM +TS+WA+LYF+ALMTFGNYVLFNLLVAILVEGFS+ +RL E + + + + + + ++ + + + ++ L S I+ + N +S PP+I HTAATPM TP+ SP N + T + S +S LS++ SF S R N + Q AS ++ + +S +++ +F H ++PT + + S+ + Y + N P L Q S+ NSF R+ + +SI + E LSRQ+SF S +R SL S + + NY+ + PD + + R N ++ D + ++ CP+P+G F +R+ ++ Y+ S +N R+ H++ +K FD VL FI LNCITLAMERP IPP S ER FL TNY+FT +FT EM+IKV +KG IG AY KSGWN+MDGFLV ISL+D+FI+I S +IFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKG FYYC G ++ V +N CL+ +NEW NQKYNFDNLGQALMALFVL+SKDGWVQIMYTG+DAVGV+ QP EN+NEW LIYFISFLLLVAFFVLNMFVGVVVENFHKC+E+QE EE+A+RAA KR K +R P YW NYS R I++V+ SKYFDLAIA VIGLNVITMA E+H MP+ L ALK+FN+FFTS F+LE+++K++ALG RYI D+WNQLD++IVILS+ G+V++E+ + F+PINPTI+RVMRVLRIARVLKLLKMA GIRALLDTVIQALPQVGNLGLLFFLLF+IFAALGVELFGRL+C D PC GLG+HAHF+NFGMAFLTLFR+ATGDNWNGIMKDTLREKC S++C ++CCVS +IAP+YFV+FVLMAQFVLVNVVVAVLMKHLEESH+MM DD L R+ + + A ++ +E+N Sbjct: 707 QKRLKYFVESNFFQRSILVAILLNTLSMGVEYHNQPEELTIVLEYSNIVFCVMFGTEMTFKIFAYGLFGYISNGFNVFDGFIVILSIVELAQPGENGASGLSVLRTFRLLRILKLVRFMPALRRQLVVMLRTMDNVATFFALLVLFMFIFSILGMNLFGCKFCRRLEDGSRKCDRKNFDSLLWAIITVFQVLTQEDWNTVLYNGMAKTSTWASLYFVALMTFGNYVLFNLLVAILVEGFSTEDEEKKKEKIKETDAADKDEEDEEEKEKQRLAENNNIDDVQSTKSCLNSVDLDVKNNKEKEKKMLALPPSSAPIIKTESPPPNHGFTSSDGPLNPPLITHTAATPMATPQGSPNENAIKDTNNKLSVSVKRSALKSTLSVDSDKSPSFRGGSPRPSPCLRRTNSRGSHHQRSASWRARNRRLRGDKTSLVVDSLSDSADDVEDDVFSSSH---SQSPTYSAGTPRTPSVNTHGHAVTYVFSDCNGHPPLNNQRALSPQSSLKGRALTPRNSFKSHHTWSRNNSV-GSGRSICNSFE--LSRQNSFTS----------------HRTVNSLGSGNSKDDKSNKNYV-------DLPDVKIALDKEEGRENEADEADPDAIDETEWNCSWCPEPRGCFLERHEYAFYLLSNENSLRKLAHHLISRKWFDNTVLIFIALNCITLAMERPDIPPESVERHFLIYTNYVFTFVFTIEMLIKVTAKGFFIGKHAYFKSGWNVMDGFLVIISLIDIFISITASSSPKIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGTFYYCRGLNVTHVTNRNQCLEDKKNEWVNQKYNFDNLGQALMALFVLASKDGWVQIMYTGLDAVGVDKQPIENYNEWRLIYFISFLLLVAFFVLNMFVGVVVENFHKCRESQEIEERAKRAAKRQEKLDKKRKSEAPKALSEMREPPYWANYSHSRLLIHTVINSKYFDLAIAAVIGLNVITMAMEYHTMPEELTFALKIFNFFFTSVFILESVMKIIALGFLRYIKDRWNQLDILIVILSVVGIVLEEMRTTFIPINPTIIRVMRVLRIARVLKLLKMAKGIRALLDTVIQALPQVGNLGLLFFLLFFIFAALGVELFGRLDC-DREPCEGLGKHAHFKNFGMAFLTLFRVATGDNWNGIMKDTLREKCDRSDNCLKDCCVSPLIAPVYFVVFVLMAQFVLVNVVVAVLMKHLEESHRMMDDDTILLRDALITITKAADNPDSKESGLEEDN 1954 HSP 2 Score: 388.652 bits (997), Expect = 5.441e-105 Identity = 258/520 (49.62%), Postives = 337/520 (64.81%), Query Frame = 1 Query: 418 MTIIAVNCITLSMYQPCGDQNCETSKCQIMQAFDYIIFAFFTCEMVIKIIAMGFLGDLGYFGDTWNRLDMFIVIVGSIEILPS-------TGNNIGLTAIRTIRVLRPLRAINRIPSMRIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQMWQGVLRNRCYLNLNESFRHPGLNLSSFYQINRTLFLNAVDKDFICSTDKNNGILKCSDIPPSIMLLSNNSLQICKQPARPFTDNLPTK-HSCVNWNQYYTDCQPGEKNPYEGAINFDNIGFAWVAIFQVISMESWVDIMYYVQDAHSFWDWIYFVALIIIGSFFMINLCLVVIASQFSETKRRETERMWIERRRFNSSNCSSI-SKDEPQTCYLEXXXXXXXXXXXXYRRIVKLYNQIQ-------------IRHSKTAQGNYQNKLKRQRKHCNVCLNSRSQFPIDDHCHLYSIVNTISGDKQ---HYYAINKYPINFSNIP--------PKASPELSVIDVLNSPRHPNHLISDISSKSVSTETK 1878 M +I +NC+TL MYQPC D+ C+T +C++++ FD+ IFAFF EM IK+IAMG G Y D+WNRLD FIV+ G E + + N+ L+AIRT+RVLRPLRAINRIPSMRILVMLLLDTLPMLGNVLLLCFFVFFIFGIIGVQ+W GVLR RC+L L E+ P +F + ++ + ++ICS +GI KC D PP + C AR +DN+P SCVNWNQYYT C+ +NPY+GA++FDNIG AWVAIFQVIS+ESWV+IMY+VQDAHSFWDWIYFVALI+IGSFFMINLCLVVIA+QFSETK+RETERM ER+RF S CS++ S EP CY E++KLI Q+ ++ R+++K Y + + R +G K +QR S + H H++ +V + S Q H+ ++ I + + P P+ASPE S ID ++SPR PN+L+ S+ S++ ++ Sbjct: 1 MFVIILNCVTLGMYQPCNDE-CDTFRCKLLENFDHFIFAFFAVEMGIKMIAMGVAGKDTYLADSWNRLDCFIVVAGLAEYIVNKTIEYSVNTENLSLSAIRTVRVLRPLRAINRIPSMRILVMLLLDTLPMLGNVLLLCFFVFFIFGIIGVQLWSGVLRRRCFLELPENVSVP-----AFVPL---YYIKSPKIEYICSPFNESGISKCQDFPPF-----HYEGIACNATARNDSDNVPVNGSSCVNWNQYYTSCEERGENPYQGAVSFDNIGLAWVAIFQVISLESWVNIMYFVQDAHSFWDWIYFVALIVIGSFFMINLCLVVIATQFSETKKRETERMLQERKRFQS--CSTLASNSEPAGCYTELLKLIAQMYRRVKRKLIKTYYKTRGMQKINPEKSLSLRRKKSKKKGTNIQKSLQQRFSIVHPHTSSHPATVHHHQHMH-LVPSHSPQPQHPVHHISLVTPDIRYQSPPRPSSTPQAPRASPEQSDIDSMSSPRRPNYLVLPSSNYSLNPSSE 503 HSP 3 Score: 113.62 bits (283), Expect = 6.144e-21 Identity = 71/279 (25.45%), Postives = 134/279 (48.03%), Query Frame = 1 Query: 3856 NQFRQKCQHIVDKKSFDYLVLFFITLNCITLAMERPSIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKFYYCDGPHLQAVKTKNDCLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENF 4692 N +++ ++ V+ F +L I LN +++ +E + P + + L +N +F ++F EM K+ + GL Y+ +G+N+ DGF+V +S+++L G S +LR FRLLR L+ +R + P L+ + +L ++ + + F IF ILG+ LF KF C + K + NFD+L A++ +F + +++ W ++Y G+ WA +YF++ + + + N+ V ++VE F Sbjct: 704 NGMQKRLKYFVESNFFQRSILVAILLNTLSMGVEYHNQP--EELTIVLEYSNIVFCVMFGTEMTFKIFAYGLF----GYISNGFNVFDGFIVILSIVELAQPGENGASG--LSVLRTFRLLRILKLVRFM---PALRRQLVVMLRTMDNVATFFALLVLFMFIFSILGMNLFGCKF----------------CRRLEDGSRKCDRKNFDSLLWAIITVFQVLTQEDWNTVLYNGMAKTST----------WASLYFVALMTFGNYVLFNLLVAILVEGF 945 HSP 4 Score: 103.219 bits (256), Expect = 7.354e-18 Identity = 92/335 (27.46%), Postives = 150/335 (44.78%), Query Frame = 1 Query: 3916 LFFITLNCITLAMERPSIPPHSKER--LFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGI-LRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKG--------------------KFYYCDGPHLQAV---------------------------KTKND----------CLKYSQ-----NEWKNQKY----NFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFHKCQENQ 4713 +F I LNC+TL M +P R L ++IF F EM IK+++ G+ G YL WN +D F+V L + + + +S + L R +R LRPLR I+R P ++++V LL +L +GN++L+C F IFGI+GVQL+ G YY P ++ + +ND C+ ++Q E Y +FDN+G A +A+F + S + WV IMY DA H+ W IYF++ +++ +FF++N+ + V+ F + ++ + Sbjct: 1 MFVIILNCVTLGMYQPCNDECDTFRCKLLENFDHFIFAF-FAVEMGIKMIAMGV-AGKDTYLADSWNRLDCFIVVAGLAEYIVNKTIEYSVNTENLSLSAIRTVRVLRPLRAINRIPSMRILVMLLLDTLPMLGNVLLLCFFVFFIFGIIGVQLWSGVLRRRCFLELPENVSVPAFVPLYYIKSPKIEYICSPFNESGISKCQDFPPFHYEGIACNATARNDSDNVPVNGSSCVNWNQYYTSCEERGENPYQGAVSFDNIGLAWVAIFQVISLESWVNIMYFVQDA----------HSFWDWIYFVALIVIGSFFMINLCLVVIATQFSETKKRE 323 HSP 5 Score: 68.9366 bits (167), Expect = 1.764e-7 Identity = 49/172 (28.49%), Postives = 80/172 (46.51%), Query Frame = 1 Query: 214 GNKSDFNLTDKSKADHCQQETDGTPINPNESLIYHGFYATVFHIFHQNKHPRDWCLKIITWPWFEQLSMTIIAVNCITLSMYQPCGDQNCETSKCQIMQAFDYIIFAFFTCEMVIKIIAMGF-LGDLGYFGDTWNRLDMFIVIVGSIEILPSTGNNIGLTAIRTIRVLRPLR 726 G +++ + D D + P P + YA F++ R +I+ WF+ + IA+NCITL+M +P D E+ + + +Y+ FT EM+IK+ A GF +G YF WN +D F+VI+ I+I I +TA + ++ LR Sbjct: 1284 GRENEADEADPDAIDETEWNCSWCP-EPRGCFLERHEYA--FYLLSNENSLRKLAHHLISRKWFDNTVLIFIALNCITLAMERP--DIPPESVERHFLIYTNYVFTFVFTIEMLIKVTAKGFFIGKHAYFKSGWNVMDGFLVIISLIDIF------ISITASSSPKIFGILR 1444
BLAST of Voltage-dependent T-type calcium channel subunit alpha vs. TrEMBL
Match: A0A2C9KE95 (Uncharacterized protein OS=Biomphalaria glabrata OX=6526 GN=106079304 PE=3 SV=1) HSP 1 Score: 1117.84 bits (2890), Expect = 0.000e+0 Identity = 689/1248 (55.21%), Postives = 854/1248 (68.43%), Query Frame = 1 Query: 2155 QQKIKTLVNDVKFQRGILIAILINTLSMGIEYHQQPVQLTQTLEFSNIVFSILFLIEMILKLIGEGILGYIKNGFNLFDGIIVVLGVIELCQQG--GTSGLSILRTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKFCT-IENNKRTCDRKNFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTSSWAALYFIALMTFGNYVLFNLLVAILVEGFSS----------------------------ERLDEQKLLHNYRQSLKKRRANNKQLRIMQHQSENLVLLTNS----IQKDQTGENQKISSQ-----PPVIIHTAATPMPTPRSSP-YNELVXXXXXXXXXXXXXXXQSILSINK----SFETTSSR--------NINTTILQEDAS---------------IMPGMKNSKQNLDSTLFVEHHIPVQKTPTSNGLNVKLVSI-----PIPYTTNRSNFIIP---SSILLRQGSI--------NSFMGSVNSDRSKILLDEKKSISETDEKSLSRQSSFKSFMAYKNKINQLTIPFSNRYSLSLDSEGKSNYQFKMNYLLAREKALEEPDDSNSESQNSSRMNNVEDPDEEDMEAMICLSKCCPQPKGIFAKRYYHSLYVFSVDNQFRQKCQHIVDKKSFDYLVLFFITLNCITLAMERPSIPPHS----KERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKFYYCDGPHLQAVKTKNDCLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFHKCQENQXXXXXXXXXX--------XXXXXXXXXXXHLRAPLYWENYSKWRRTINSVVTSKYFDLAIAGVIGLNVITMATEFHMMPQVLKTALKVFNYFFTSTFVXXXXXXXXXXXXXRYISDKWNQLDMMIVILSIAGVVIDEVESNFMPINPTIMRVMRVLRIARVLKLLKMASGIRALLDTVIQALPQVGNXXXXXXXXXXXXXXXXVELFGRLECSDINPCVGLGRHAHFENFGMAFLTLFRIATGDNWNGIMKDTLREKCISSEDCQRNCCVSAIIAPIYFVIFXXXXXXXXXXXXXXXXXKHLEESHK 5610 Q+++K V FQR IL+AIL+NTLSMG+EYH QP +LT LE+SNIVF ++F EM K+ G+ GYI NGFN+FDG IV+L ++EL Q G G SGLS+LRTFRLLRILKLVRFMPALR+QL VM+RT+DNVATFFALL+LF+FIFSILGM+LFGCKFC +E+ R CDRKNFDSLLW+I+TVFQ+LTQEDWNTVLYNGM +TS+WA+LYF+ALMTFGNYVLFNLLVAILVEGFS+ +RL E + + + + + + ++ + + + ++ L S I+ + N +S PP+I HTAATPM TP+ SP N + T + S +S LS++ SF S R N + Q AS ++ + +S +++ +F H ++PT + + S+ + Y + N P L Q S+ NSF R+ + +SI + E LSRQ+SF S +R SL S + + NY+ + PD + + R N ++ D + ++ CP+P+G F +R+ ++ Y+ S +N R+ H++ +K FD VL FI LNCITLAMERP IPP S +ER FL TNY+FT +FT EM+IKV +KG IG AY KSGWN+MDGFLV ISL+D+FI+I S +IFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKG FYYC G ++ V +N CL+ +NEW NQKYNFDNLGQALMALFVL+SKDGWVQIMYTG+DAVGV+ QP EN+NEW LIYFISFLLLVAFFVLNMFVGVVVENFHKC+E+QE EE+A+RAA KR K +R P YW NYS R I++V+ SKYFDLAIA VIGLNVITMA E+H MP+ L ALK+FN+FFTS F+LE+++K++ALG RYI D+WNQLD++IVILS+ G+V++E+ + F+PINPTI+RVMRVLRIARVLKLLKMA GIRALLDTVIQALPQVGNLGLLFFLLF+IFAALGVELFGRL+C D PC GLG+HAHF+NFGMAFLTLFR+ATGDNWNGIMKDTLREKC S++C ++CCVS +IAP+YFV+FVLMAQFVLVNVVVAVLMKHLEE++K Sbjct: 707 QKRLKYFVESNFFQRSILVAILLNTLSMGVEYHNQPEELTIVLEYSNIVFCVMFGTEMTFKIFAYGLFGYISNGFNVFDGFIVILSIVELAQPGENGASGLSVLRTFRLLRILKLVRFMPALRRQLVVMLRTMDNVATFFALLVLFMFIFSILGMNLFGCKFCRRLEDGSRKCDRKNFDSLLWAIITVFQVLTQEDWNTVLYNGMAKTSTWASLYFVALMTFGNYVLFNLLVAILVEGFSTEDEEKKKEKIKETDAADKDEEDEEEKEKQRLAENNNIDDVQSTKSCLNSVDLDVKNNKEKEKKMLALPPSSAPIIKTESPPPNHGFTSSDGPLNPPLITHTAATPMATPQGSPNENAIKDTNNKLSVSVKRSALKSTLSVDSDKSPSFRGGSPRPSPCLRRTNSRGSHHQRSASWRARNRRLRGDKTSLVVDSLSDSADDVEDDVFSSSH---SQSPTYSAGTPRTPSVNTHGHAVTYVFSDCNGHPPLNNQRALSPQSSLKGRALTPRNSFKSHHTWSRNNSV-GSGRSICNSFE--LSRQNSFTS----------------HRTVNSLGSGNSKDDKSNKNYV-------DLPDVKIALDKEEGRENEADEADPDAIDETEWNCSWCPEPRGCFLERHEYAFYLLSNENSLRKLAHHLISRKWFDNTVLIFIALNCITLAMERPDIPPESVVSYEERHFLIYTNYVFTFVFTIEMLIKVTAKGFFIGKHAYFKSGWNVMDGFLVIISLIDIFISITASSSPKIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGTFYYCRGLNVTHVTNRNQCLEDKKNEWVNQKYNFDNLGQALMALFVLASKDGWVQIMYTGLDAVGVDKQPIENYNEWRLIYFISFLLLVAFFVLNMFVGVVVENFHKCRESQEIEERAKRAAKRQEKLDKKRKSEAPKALSEMREPPYWANYSHSRLLIHTVINSKYFDLAIAAVIGLNVITMAMEYHTMPEELTFALKIFNFFFTSVFILESVMKIIALGFLRYIKDRWNQLDILIVILSVVGIVLEEMRTTFIPINPTIIRVMRVLRIARVLKLLKMAKGIRALLDTVIQALPQVGNLGLLFFLLFFIFAALGVELFGRLDC-DREPCEGLGKHAHFKNFGMAFLTLFRVATGDNWNGIMKDTLREKCDRSDNCLKDCCVSPLIAPVYFVVFVLMAQFVLVNVVVAVLMKHLEETYK 1924 HSP 2 Score: 389.037 bits (998), Expect = 5.136e-105 Identity = 256/519 (49.33%), Postives = 337/519 (64.93%), Query Frame = 1 Query: 418 MTIIAVNCITLSMYQPCGDQNCETSKCQIMQAFDYIIFAFFTCEMVIKIIAMGFLGDLGYFGDTWNRLDMFIVIVGSIEILPS-------TGNNIGLTAIRTIRVLRPLRAINRIPSMRIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQMWQGVLRNRCYLNLNESFRHPGLNLSSFYQINRTLFLNAVDKDFICSTDKNNGILKCSDIPPSIMLLSNNSLQICKQPARPFTDNLPTK-HSCVNWNQYYTDCQPGEKNPYEGAINFDNIGFAWVAIFQVISMESWVDIMYYVQDAHSFWDWIYFVALIIIGSFFMINLCLVVIASQFSETKRRETERMWIERRRFNSSNCSSI-SKDEPQTCYLEXXXXXXXXXXXXYRRIVKLYNQIQIRHSKTAQGNY-----------QNKLKRQRKHCNVCLNSRSQFPIDDHCHLY-SIVNTISGDKQ---HYYAINKYPINFSNIP--------PKASPELSVIDVLNSPRHPNHLISDISSKSVSTETK 1878 M +I +NC+TL MYQPC D+ C+T +C++++ FD+ IFAFF EM IK+IAMG G Y D+WNRLD FIV+ G E + + N+ L+AIRT+RVLRPLRAINRIPSMRILVMLLLDTLPMLGNVLLLCFFVFFIFGIIGVQ+W GVLR RC+L L E+ P +F + ++ + ++ICS +GI KC D PP + C AR +DN+P SCVNWNQYYT C+ +NPY+GA++FDNIG AWVAIFQVIS+ESWV+IMY+VQDAHSFWDWIYFVALI+IGSFFMINLCLVVIA+QFSETK+RETERM ER+RF S CS++ S EP CY E++KLI Q+ ++ R+++K Y + + + + N K ++ ++ S P H H + +V + S Q H+ ++ I + + P P+ASPE S ID ++SPR PN+L+ S+ S++ ++ Sbjct: 1 MFVIILNCVTLGMYQPCNDE-CDTFRCKLLENFDHFIFAFFAVEMGIKMIAMGVAGKDTYLADSWNRLDCFIVVAGLAEYIVNKTIEYSVNTENLSLSAIRTVRVLRPLRAINRIPSMRILVMLLLDTLPMLGNVLLLCFFVFFIFGIIGVQLWSGVLRRRCFLELPENVSVP-----AFVPL---YYIKSPKIEYICSPFNESGISKCQDFPPF-----HYEGIACNATARNDSDNVPVNGSSCVNWNQYYTSCEERGENPYQGAVSFDNIGLAWVAIFQVISLESWVNIMYFVQDAHSFWDWIYFVALIVIGSFFMINLCLVVIATQFSETKKRETERMLQERKRFQS--CSTLASNSEPAGCYTELLKLIAQMYRRVKRKLIKTYYKTRGMQKINPEKSLSLRRKKSKKKGTNIQKSLQQRFSIVHPHTSSHPATVHHHQHMHLVPSHSPQPQHPVHHISLVTPDIRYQSPPRPSSTPQAPRASPEQSDIDSMSSPRRPNYLVLPSSNYSLNPSSE 503 HSP 3 Score: 113.62 bits (283), Expect = 6.115e-21 Identity = 71/279 (25.45%), Postives = 134/279 (48.03%), Query Frame = 1 Query: 3856 NQFRQKCQHIVDKKSFDYLVLFFITLNCITLAMERPSIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKFYYCDGPHLQAVKTKNDCLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENF 4692 N +++ ++ V+ F +L I LN +++ +E + P + + L +N +F ++F EM K+ + GL Y+ +G+N+ DGF+V +S+++L G S +LR FRLLR L+ +R + P L+ + +L ++ + + F IF ILG+ LF KF C + K + NFD+L A++ +F + +++ W ++Y G+ WA +YF++ + + + N+ V ++VE F Sbjct: 704 NGMQKRLKYFVESNFFQRSILVAILLNTLSMGVEYHNQP--EELTIVLEYSNIVFCVMFGTEMTFKIFAYGLF----GYISNGFNVFDGFIVILSIVELAQPGENGASG--LSVLRTFRLLRILKLVRFM---PALRRQLVVMLRTMDNVATFFALLVLFMFIFSILGMNLFGCKF----------------CRRLEDGSRKCDRKNFDSLLWAIITVFQVLTQEDWNTVLYNGMAKTST----------WASLYFVALMTFGNYVLFNLLVAILVEGF 945 HSP 4 Score: 103.605 bits (257), Expect = 6.726e-18 Identity = 92/335 (27.46%), Postives = 150/335 (44.78%), Query Frame = 1 Query: 3916 LFFITLNCITLAMERPSIPPHSKER--LFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGI-LRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKG--------------------KFYYCDGPHLQAV---------------------------KTKND----------CLKYSQ-----NEWKNQKY----NFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFHKCQENQ 4713 +F I LNC+TL M +P R L ++IF F EM IK+++ G+ G YL WN +D F+V L + + + +S + L R +R LRPLR I+R P ++++V LL +L +GN++L+C F IFGI+GVQL+ G YY P ++ + +ND C+ ++Q E Y +FDN+G A +A+F + S + WV IMY DA H+ W IYF++ +++ +FF++N+ + V+ F + ++ + Sbjct: 1 MFVIILNCVTLGMYQPCNDECDTFRCKLLENFDHFIFAF-FAVEMGIKMIAMGV-AGKDTYLADSWNRLDCFIVVAGLAEYIVNKTIEYSVNTENLSLSAIRTVRVLRPLRAINRIPSMRILVMLLLDTLPMLGNVLLLCFFVFFIFGIIGVQLWSGVLRRRCFLELPENVSVPAFVPLYYIKSPKIEYICSPFNESGISKCQDFPPFHYEGIACNATARNDSDNVPVNGSSCVNWNQYYTSCEERGENPYQGAVSFDNIGLAWVAIFQVISLESWVNIMYFVQDA----------HSFWDWIYFVALIVIGSFFMINLCLVVIATQFSETKKRE 323 HSP 5 Score: 64.6994 bits (156), Expect = 3.858e-6 Identity = 50/176 (28.41%), Postives = 80/176 (45.45%), Query Frame = 1 Query: 214 GNKSDFNLTDKSKADHCQQETDGTPINPNESLIYHGFYATVFHIFHQNKHPRDWCLKIITWPWFEQLSMTIIAVNCITLSMYQPCGDQNCETSKCQIMQAF----DYIIFAFFTCEMVIKIIAMGF-LGDLGYFGDTWNRLDMFIVIVGSIEILPSTGNNIGLTAIRTIRVLRPLR 726 G +++ + D D + P P + YA F++ R +I+ WF+ + IA+NCITL+M +P D E+ + F +Y+ FT EM+IK+ A GF +G YF WN +D F+VI+ I+I I +TA + ++ LR Sbjct: 1284 GRENEADEADPDAIDETEWNCSWCP-EPRGCFLERHEYA--FYLLSNENSLRKLAHHLISRKWFDNTVLIFIALNCITLAMERP--DIPPESVVSYEERHFLIYTNYVFTFVFTIEMLIKVTAKGFFIGKHAYFKSGWNVMDGFLVIISLIDIF------ISITASSSPKIFGILR 1448
BLAST of Voltage-dependent T-type calcium channel subunit alpha vs. TrEMBL
Match: A0A2C9KE61 (Uncharacterized protein OS=Biomphalaria glabrata OX=6526 GN=106079304 PE=3 SV=1) HSP 1 Score: 1115.14 bits (2883), Expect = 0.000e+0 Identity = 695/1293 (53.75%), Postives = 866/1293 (66.98%), Query Frame = 1 Query: 2155 QQKIKTLVNDVKFQRGILIAILINTLSMGIEYHQQPVQLTQTLEFSNIVFSILFLIEMILKLIGEGILGYIKNGFNLFDGIIVVLGVIELCQQG--GTSGLSILRTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKFCTIENNKR------------TCDRKNFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTSSWAALYFIALMTFGNYVLFNLLVAILVEGFSS----------------------------ERLDEQKLLHNYRQSLKKRRANNKQLRIMQHQSENLVLLTNS----IQKDQTGENQKISSQ-----PPVIIHTAATPMPTPRSSP-YNELVXXXXXXXXXXXXXXXQSILSINK----SFETTSSR--------NINTTILQEDAS---------------IMPGMKNSKQNLDSTLFVEHHIPVQKTPTSNGLNVKLVSI-----PIPYTTNRSNFIIP---SSILLRQGSI--------NSFMGSVNSDRSKILLDEKKSISETDEKSLSRQSSFKSFMAYKNKINQLTIPFSNRYSLSLDSEGKSNYQFKMNYLLAREKALEEPDDSNSESQNSSRMNNVEDPDEEDMEAMICLSKCCPQPKGIFAKRYYHSLYVFSVDNQFRQKCQHIVDKKSFDYLVLFFITLNCITLAMERPSIPPHS----KERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKFYYCDGPHLQAVKTKNDCLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFHKCQENQXXXXXXXXXX--------XXXXXXXXXXXHLRAPLYWENYSKWRRTINSVVTSKYFDLAIAGVIGLNVITMATEFHMMPQVLKTALKVFNYFFTSTFVXXXXXXXXXXXXXRYISDKWNQLDMMIVILSIAGVVIDEVESNFMPINPTIMRVMRVLRIARVLKLLKMASGIRALLDTVIQALPQVGNXXXXXXXXXXXXXXXXVELFGRLECSDINPCVGLGRHAHFENFGMAFLTLFRIATGDNWNGIMKDTLREKCISSEDCQRNCCVSAIIAPIYFVIFXXXXXXXXXXXXXXXXXKHLEESHKMMCDDYELEREVQRDLDEEAKELAREKQLKDEEN 5712 Q+++K V FQR IL+AIL+NTLSMG+EYH QP +LT LE+SNIVF ++F EM K+ G+ GYI NGFN+FDG IV+L ++EL Q G G SGLS+LRTFRLLRILKLVRFMPALR+QL VM+RT+DNVATFFALL+LF+FIFSILGM+LFG FC +E+ CDR NFD+LLWS+VTVFQ+LTQEDWNTVLYNGM +TS+WA+LYF+ALMTFGNYVLFNLLVAILVEGFS+ +RL E + + + + + + ++ + + + ++ L S I+ + N +S PP+I HTAATPM TP+ SP N + T + S +S LS++ SF S R N + Q AS ++ + +S +++ +F H ++PT + + S+ + Y + N P L Q S+ NSF R+ + +SI + E LSRQ+SF S +R SL S + + NY+ + PD + + R N ++ D + ++ CP+P+G F +R+ ++ Y+ S +N R+ H++ +K FD VL FI LNCITLAMERP IPP S +ER FL TNY+FT +FT EM+IKV +KG IG AY KSGWN+MDGFLV ISL+D+FI+I S +IFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKG FYYC G ++ V +N CL+ +NEW NQKYNFDNLGQALMALFVL+SKDGWVQIMYTG+DAVGV+ QP EN+NEW LIYFISFLLLVAFFVLNMFVGVVVENFHKC+E+QE EE+A+RAA KR K +R P YW NYS R I++V+ SKYFDLAIA VIGLNVITMA E+H MP+ L ALK+FN+FFTS F+LE+++K++ALG RYI D+WNQLD++IVILS+ G+V++E+ + F+PINPTI+RVMRVLRIARVLKLLKMA GIRALLDTVIQALPQVGNLGLLFFLLF+IFAALGVELFGRL+C D PC GLG+HAHF+NFGMAFLTLFR+ATGDNWNGIMKDTLREKC S++C ++CCVS +IAP+YFV+FVLMAQFVLVNVVVAVLMKHLEESH+MM DD L R+ + + A ++ +E+N Sbjct: 707 QKRLKYFVESNFFQRSILVAILLNTLSMGVEYHNQPEELTIVLEYSNIVFCVMFGTEMTFKIFAYGLFGYISNGFNVFDGFIVILSIVELAQPGENGASGLSVLRTFRLLRILKLVRFMPALRRQLVVMLRTMDNVATFFALLVLFMFIFSILGMNLFGGSFCEMEDGTACSCKERCNASLCKCDRANFDNLLWSLVTVFQVLTQEDWNTVLYNGMAKTSTWASLYFVALMTFGNYVLFNLLVAILVEGFSTEDEEKKKEKIKETDAADKDEEDEEEKEKQRLAENNNIDDVQSTKSCLNSVDLDVKNNKEKEKKMLALPPSSAPIIKTESPPPNHGFTSSDGPLNPPLITHTAATPMATPQGSPNENAIKDTNNKLSVSVKRSALKSTLSVDSDKSPSFRGGSPRPSPCLRRTNSRGSHHQRSASWRARNRRLRGDKTSLVVDSLSDSADDVEDDVFSSSH---SQSPTYSAGTPRTPSVNTHGHAVTYVFSDCNGHPPLNNQRALSPQSSLKGRALTPRNSFKSHHTWSRNNSV-GSGRSICNSFE--LSRQNSFTS----------------HRTVNSLGSGNSKDDKSNKNYV-------DLPDVKIALDKEEGRENEADEADPDAIDETEWNCSWCPEPRGCFLERHEYAFYLLSNENSLRKLAHHLISRKWFDNTVLIFIALNCITLAMERPDIPPESVVSYEERHFLIYTNYVFTFVFTIEMLIKVTAKGFFIGKHAYFKSGWNVMDGFLVIISLIDIFISITASSSPKIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGTFYYCRGLNVTHVTNRNQCLEDKKNEWVNQKYNFDNLGQALMALFVLASKDGWVQIMYTGLDAVGVDKQPIENYNEWRLIYFISFLLLVAFFVLNMFVGVVVENFHKCRESQEIEERAKRAAKRQEKLDKKRKSEAPKALSEMREPPYWANYSHSRLLIHTVINSKYFDLAIAAVIGLNVITMAMEYHTMPEELTFALKIFNFFFTSVFILESVMKIIALGFLRYIKDRWNQLDILIVILSVVGIVLEEMRTTFIPINPTIIRVMRVLRIARVLKLLKMAKGIRALLDTVIQALPQVGNLGLLFFLLFFIFAALGVELFGRLDC-DREPCEGLGKHAHFKNFGMAFLTLFRVATGDNWNGIMKDTLREKCDRSDNCLKDCCVSPLIAPVYFVVFVLMAQFVLVNVVVAVLMKHLEESHRMMDDDTILLRDALITITKAADNPDSKESGLEEDN 1969 HSP 2 Score: 388.652 bits (997), Expect = 5.546e-105 Identity = 258/520 (49.62%), Postives = 337/520 (64.81%), Query Frame = 1 Query: 418 MTIIAVNCITLSMYQPCGDQNCETSKCQIMQAFDYIIFAFFTCEMVIKIIAMGFLGDLGYFGDTWNRLDMFIVIVGSIEILPS-------TGNNIGLTAIRTIRVLRPLRAINRIPSMRIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQMWQGVLRNRCYLNLNESFRHPGLNLSSFYQINRTLFLNAVDKDFICSTDKNNGILKCSDIPPSIMLLSNNSLQICKQPARPFTDNLPTK-HSCVNWNQYYTDCQPGEKNPYEGAINFDNIGFAWVAIFQVISMESWVDIMYYVQDAHSFWDWIYFVALIIIGSFFMINLCLVVIASQFSETKRRETERMWIERRRFNSSNCSSI-SKDEPQTCYLEXXXXXXXXXXXXYRRIVKLYNQIQ-------------IRHSKTAQGNYQNKLKRQRKHCNVCLNSRSQFPIDDHCHLYSIVNTISGDKQ---HYYAINKYPINFSNIP--------PKASPELSVIDVLNSPRHPNHLISDISSKSVSTETK 1878 M +I +NC+TL MYQPC D+ C+T +C++++ FD+ IFAFF EM IK+IAMG G Y D+WNRLD FIV+ G E + + N+ L+AIRT+RVLRPLRAINRIPSMRILVMLLLDTLPMLGNVLLLCFFVFFIFGIIGVQ+W GVLR RC+L L E+ P +F + ++ + ++ICS +GI KC D PP + C AR +DN+P SCVNWNQYYT C+ +NPY+GA++FDNIG AWVAIFQVIS+ESWV+IMY+VQDAHSFWDWIYFVALI+IGSFFMINLCLVVIA+QFSETK+RETERM ER+RF S CS++ S EP CY E++KLI Q+ ++ R+++K Y + + R +G K +QR S + H H++ +V + S Q H+ ++ I + + P P+ASPE S ID ++SPR PN+L+ S+ S++ ++ Sbjct: 1 MFVIILNCVTLGMYQPCNDE-CDTFRCKLLENFDHFIFAFFAVEMGIKMIAMGVAGKDTYLADSWNRLDCFIVVAGLAEYIVNKTIEYSVNTENLSLSAIRTVRVLRPLRAINRIPSMRILVMLLLDTLPMLGNVLLLCFFVFFIFGIIGVQLWSGVLRRRCFLELPENVSVP-----AFVPL---YYIKSPKIEYICSPFNESGISKCQDFPPF-----HYEGIACNATARNDSDNVPVNGSSCVNWNQYYTSCEERGENPYQGAVSFDNIGLAWVAIFQVISLESWVNIMYFVQDAHSFWDWIYFVALIVIGSFFMINLCLVVIATQFSETKKRETERMLQERKRFQS--CSTLASNSEPAGCYTELLKLIAQMYRRVKRKLIKTYYKTRGMQKINPEKSLSLRRKKSKKKGTNIQKSLQQRFSIVHPHTSSHPATVHHHQHMH-LVPSHSPQPQHPVHHISLVTPDIRYQSPPRPSSTPQAPRASPEQSDIDSMSSPRRPNYLVLPSSNYSLNPSSE 503 HSP 3 Score: 119.013 bits (297), Expect = 1.264e-22 Identity = 75/279 (26.88%), Postives = 139/279 (49.82%), Query Frame = 1 Query: 3856 NQFRQKCQHIVDKKSFDYLVLFFITLNCITLAMERPSIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKFYYCDGPHLQAVKTKNDCLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENF 4692 N +++ ++ V+ F +L I LN +++ +E + P + + L +N +F ++F EM K+ + GL Y+ +G+N+ DGF+V +S+++L G S +LR FRLLR L+ +R + P L+ + +L ++ + + F IF ILG+ LF G F C+ A K C + + K + NFDNL +L+ +F + +++ W ++Y G+ WA +YF++ + + + N+ V ++VE F Sbjct: 704 NGMQKRLKYFVESNFFQRSILVAILLNTLSMGVEYHNQP--EELTIVLEYSNIVFCVMFGTEMTFKIFAYGLF----GYISNGFNVFDGFIVILSIVELAQPGENGASG--LSVLRTFRLLRILKLVRFM---PALRRQLVVMLRTMDNVATFFALLVLFMFIFSILGMNLFGGSF--CEMEDGTACSCKERC---NASLCKCDRANFDNLLWSLVTVFQVLTQEDWNTVLYNGMAKTST----------WASLYFVALMTFGNYVLFNLLVAILVEGF 956 HSP 4 Score: 103.605 bits (257), Expect = 5.819e-18 Identity = 92/335 (27.46%), Postives = 150/335 (44.78%), Query Frame = 1 Query: 3916 LFFITLNCITLAMERPSIPPHSKER--LFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGI-LRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKG--------------------KFYYCDGPHLQAV---------------------------KTKND----------CLKYSQ-----NEWKNQKY----NFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFHKCQENQ 4713 +F I LNC+TL M +P R L ++IF F EM IK+++ G+ G YL WN +D F+V L + + + +S + L R +R LRPLR I+R P ++++V LL +L +GN++L+C F IFGI+GVQL+ G YY P ++ + +ND C+ ++Q E Y +FDN+G A +A+F + S + WV IMY DA H+ W IYF++ +++ +FF++N+ + V+ F + ++ + Sbjct: 1 MFVIILNCVTLGMYQPCNDECDTFRCKLLENFDHFIFAF-FAVEMGIKMIAMGV-AGKDTYLADSWNRLDCFIVVAGLAEYIVNKTIEYSVNTENLSLSAIRTVRVLRPLRAINRIPSMRILVMLLLDTLPMLGNVLLLCFFVFFIFGIIGVQLWSGVLRRRCFLELPENVSVPAFVPLYYIKSPKIEYICSPFNESGISKCQDFPPFHYEGIACNATARNDSDNVPVNGSSCVNWNQYYTSCEERGENPYQGAVSFDNIGLAWVAIFQVISLESWVNIMYFVQDA----------HSFWDWIYFVALIVIGSFFMINLCLVVIATQFSETKKRE 323 HSP 5 Score: 64.6994 bits (156), Expect = 4.019e-6 Identity = 50/176 (28.41%), Postives = 80/176 (45.45%), Query Frame = 1 Query: 214 GNKSDFNLTDKSKADHCQQETDGTPINPNESLIYHGFYATVFHIFHQNKHPRDWCLKIITWPWFEQLSMTIIAVNCITLSMYQPCGDQNCETSKCQIMQAF----DYIIFAFFTCEMVIKIIAMGF-LGDLGYFGDTWNRLDMFIVIVGSIEILPSTGNNIGLTAIRTIRVLRPLR 726 G +++ + D D + P P + YA F++ R +I+ WF+ + IA+NCITL+M +P D E+ + F +Y+ FT EM+IK+ A GF +G YF WN +D F+VI+ I+I I +TA + ++ LR Sbjct: 1295 GRENEADEADPDAIDETEWNCSWCP-EPRGCFLERHEYA--FYLLSNENSLRKLAHHLISRKWFDNTVLIFIALNCITLAMERP--DIPPESVVSYEERHFLIYTNYVFTFVFTIEMLIKVTAKGFFIGKHAYFKSGWNVMDGFLVIISLIDIF------ISITASSSPKIFGILR 1459
BLAST of Voltage-dependent T-type calcium channel subunit alpha vs. Ensembl Cavefish
Match: cacna1ha (calcium channel, voltage-dependent, T type, alpha 1H subunit a [Source:ZFIN;Acc:ZDB-GENE-130103-1]) HSP 1 Score: 623.624 bits (1607), Expect = 0.000e+0 Identity = 395/678 (58.26%), Postives = 512/678 (75.52%), Query Frame = 1 Query: 3673 KALEEPDDSNSESQNSSRMNNVEDPDEEDMEAMIC--LSKCCPQPKGIFAKRYYH-SLYVFSVDNQFRQKCQHIVDKKSFDYLVLFFITLNCITLAMERPSIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKFYYCDGPHLQAVKTKNDCLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFHKCQENQXXXXXXXXXXXXXXXXXXXXXHLRAPLYWENYSKWRRTINSVVTSKYFDLAIAGVIGLNVITMATEFHMMPQVLKTALKVFNYFFTSTFVXXXXXXXXXXXXXRYISDKWNQLDMMIVILSIAGVVIDEVESN-FMPINPTIMRVMRVLRIARVLKLLKMASGIRALLDTVIQALPQVGNXXXXXXXXXXXXXXXXVELFGRLECSDINPCVGLGRHAHFENFGMAFLTLFRIATGDNWNGIMKDTLREKCISSEDCQRNCCVSAIIAPIYFVIFXXXXXXXXXXXXXXXXXKHLEESHK------MMCDDYELEREVQRDLDEEAKE 5676 +A++ P D +E +N + +EED++ C L + K + K + SLY+FS +N+FR C I+ + FD++VL FI LNCIT+A+ERP+I PHS ER+FL+++NY+FT+IF EM +KV++ +G +YL+S WNI+DG LVF+SL+D+ +++ NRI GILRV RLLRTLRPLRVISRAPGLKLVV+TL++SLRPIGNIV+IC FFIIFGILGVQLFKGKFY+C+G + + K+DCL + +W +KYNFDNLGQALM+LFVLS KDGWV IMY G+DAVGV+ QP NHN W L+YFISFLL+V+FFVLNMFVGVVVENFHKC+++QE+EE R KR R+ EK+R+ + Y+ YS R I+++ ++ Y DL I +I +NV+TM+ E + PQ L+ ALK NY FT F+LEA+LKLVA G+ R+ D+WNQLD+ IV+LSI G+ ++E++ N +PINPTI+R+MRVLRIARVLKLLKMA G+RALLDTV+QALPQVGNLGLLF LLF+I+AALGVELFG+L+C PC GL RHA FENFGMAFLTLFR++TGDNWNGIMKDTLRE CI +++C +++P+YFV FVLMAQFVLVNVVVAVLMKHLEES+K M D E+++E+Q D + + + Sbjct: 1089 RAMQLPTDLPAE------LNREDSANEEDLDDSFCCRLRRMLNAYKPQWCKDHEDWSLYMFSPENKFRVICNRIISHRLFDHVVLVFIFLNCITIALERPNIKPHSTERVFLSISNYVFTVIFLAEMTVKVVA----LGFYSYLQSTWNILDGMLVFVSLIDILVSLASSGGNRILGILRVLRLLRTLRPLRVISRAPGLKLVVETLITSLRPIGNIVVICWAFFIIFGILGVQLFKGKFYHCEGLDTRNITNKSDCL-LANYKWVPRKYNFDNLGQALMSLFVLSCKDGWVNIMYDGLDAVGVDQQPVRNHNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHKCRQDQEEEEARLREEKRRRQQEKRRRKAQKIPYYAYYSPIRLYIHTLCSNHYLDLFITFIICINVVTMSIEHYDQPQYLEEALKYCNYVFTIFFILEAILKLVAFGIRRFFKDRWNQLDLAIVLLSIMGITLEEIKMNAALPINPTIIRIMRVLRIARVLKLLKMAKGMRALLDTVMQALPQVGNLGLLFMLLFFIYAALGVELFGKLDCIK-QPCEGLSRHATFENFGMAFLTLFRVSTGDNWNGIMKDTLRE-CIPADNC---LSYLPLVSPLYFVTFVLMAQFVLVNVVVAVLMKHLEESNKEAKEEAEMDSDTEMDKEIQNDEERQGTQ 1750 HSP 2 Score: 352.058 bits (902), Expect = 1.397e-97 Identity = 211/393 (53.69%), Postives = 282/393 (71.76%), Query Frame = 1 Query: 418 MTIIAVNCITLSMYQPCGDQNCETSKCQIMQAFDYIIFAFFTCEMVIKIIAMGFLGDLGYFGDTWNRLDMFIVIVGSIEILPSTGNNIGLTAIRTIRVLRPLRAINRIPSMRIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQMWQGVLRNRCYLNLNESFRHPGLNLSSFYQINRTLFLNAVDKDFICSTDKNNGILKCSDIPPSIMLLSNNSLQICKQPARPFTDNLPTKHSCVNWNQYYTDCQPGEKNPYEGAINFDNIGFAWVAIFQVISMESWVDIMYYVQDAHSFWDWIYFVALIIIGSFFMINLCLVVIASQFSETKRRETERMWIERRRFNSSNCSSISKDEPQTCYLEXXXXXXXXXXXXYRRIVKLYNQIQIRHSKTAQGN 1596 M +I +NC+TL MYQPC D C++ C I++AFD IFAFF EMVIK++A+G G Y GDTWNRLD FIV+ G +E G+N L+AIRT+RVLRPL+AINR+PSM+ILV LLLDTLPMLGNVLLLCFFVFFIFGI+GVQ+W G+LRNRC++ N + + L++S +Y + D FICS++K NG+ +C ++PP L+ N +T + P +SCVNWNQYY C+PG+ NP++GA+NFDNIG+AW+AIFQVI++E WVDIMYYV DAHSF+++IYF+ LII+GSFFMINLCLVVIA+QFSETK+R + M +R + S++ + S EP +CY E+++ I+ + K+ RR +LY+ Q + K N Sbjct: 1 MLVILLNCVTLGMYQPCEDVACQSEWCIILRAFDDCIFAFFAVEMVIKMMALGIFGPACYLGDTWNRLDFFIVMAGMLE-YSLDGHNASLSAIRTVRVLRPLKAINRVPSMKILVTLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAGLLRNRCFMKENFTDIY-NLSMSQYYMDE-----DGEDNPFICSSEKENGMRRCRNVPP---LMENGFNCTLNASFSHYTYSDP--NSCVNWNQYYNQCRPGDLNPHKGAVNFDNIGYAWIAIFQVITLEGWVDIMYYVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQRVNKLMKDQRVCYQSNDSTLASYSEPGSCYEEMLRYISHLYRKVKRRTSRLYHGWQSKRRKKINPN 381 HSP 3 Score: 325.479 bits (833), Expect = 2.869e-89 Identity = 183/320 (57.19%), Postives = 234/320 (73.12%), Query Frame = 1 Query: 2155 QQKIKTLVNDVKFQRGILIAILINTLSMGIEYHQQPVQLTQTLEFSNIVFSILFLIEMILKLIGEGILGYIKNGFNLFDGIIVVLGVIELCQQGGTSGLSILRTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKFC-TIENNKRTCDRKNFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTSSWAALYFIALMTFGNYVLFNLLVAILVEGFSSE------RLDEQKLLHNYRQSLKKRRANNKQLRIMQHQSENLVLLTNSIQKDQTGENQKISSQPPVIIHTAATPMPTPRSS 3093 + ++K +V+ F RGI+IAILINTLSMGIE+H+QP +LT LE SNIVF+ +F++EMI KL+ GI GYIKN +N+FDGIIVV+ V E+ Q GLS+LRTFRLLR+LKLVRF+PALR+QL V+++++DNVATF LL+LFIF FSILGM LFGCKFC EN DRKNFDSLLW+IVTVFQILTQEDWN VLYNGM +S A+LYF+ALMTFGNYVLFNLLVAILVE F +E DE+K ++ + K ++L++ ++++ + + G + PP+I+ TAATPMPTP+SS Sbjct: 648 RDRMKRIVDSKYFNRGIMIAILINTLSMGIEHHEQPKELTDILEISNIVFTSMFVLEMIFKLVAFGIYGYIKNPYNIFDGIIVVISVWEIIGQA-DGGLSVLRTFRLLRVLKLVRFLPALRRQLVVLMKSMDNVATFCMLLMLFIFTFSILGMHLFGCKFCLKTENGDTIPDRKNFDSLLWAIVTVFQILTQEDWNVVLYNGMASSSPLASLYFVALMTFGNYVLFNLLVAILVEAFQAEGDANRSDSDEEKRSVDFEEEEKMGELRARELKMYS------LMMSANGHVESRG-----NLPPPIIMRTAATPMPTPKSS 955 HSP 4 Score: 113.62 bits (283), Expect = 1.993e-24 Identity = 75/293 (25.60%), Postives = 143/293 (48.81%), Query Frame = 1 Query: 3817 KRYYHSLYVFSVDNQFRQKCQHIVDKKSFDYLVLFFITLNCITLAMERPSIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKFYYCDGPHLQAVKTKNDCLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFH 4695 KR +++ FR + + IVD K F+ ++ I +N +++ +E P + L ++N +FT +F EMI K+++ G+ Y+K+ +NI DG +V IS+ + ++G ++ +LR FRLLR L+ +R + P L+ + L+ S+ + ++ F F ILG+ LF KF CLK + + NFD+L A++ +F + +++ W ++Y G+ + + A +YF++ + + + N+ V ++VE F Sbjct: 632 KRLCERIHMARYWEDFRDRMKRIVDSKYFNRGIMIAILINTLSMGIEHHEQPKELTD--ILEISNIVFTSMFVLEMIFKLVAFGIY----GYIKNPYNIFDGIIVVISVWE-----IIGQADGGLSVLRTFRLLRVLKLVRFL---PALRRQLVVLMKSMDNVATFCMLLMLFIFTFSILGMHLFGCKF----------------CLKTENGDTIPDRKNFDSLLWAIVTVFQILTQEDWNVVLYNGM----------ASSSPLASLYFVALMTFGNYVLFNLLVAILVEAFQ 884 HSP 5 Score: 88.5817 bits (218), Expect = 7.369e-17 Identity = 60/212 (28.30%), Postives = 111/212 (52.36%), Query Frame = 1 Query: 2140 YLSICQQKIKTLVNDVKFQRGILIAILINTLSMGIEYHQQPVQLTQTLEFSNIVFSILFLIEMILKLIGEGILGYIKNGFNLFDGIIVVLGVIELCQQG---------GTSGLSILRTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKFCTIENNKRTCDRKNFDSLLWSIVTVFQILTQEDWNTVL 2748 Y S + I TL ++ I I IN ++M IE++ QP L + L++ N VF+I F++E ILKL+ GI + K+ +N D IV+L ++ + + + + I+R R+ R+LKL++ +R L +++ + V L +L FI++ LG+ LFG C + + F++ + +T+F++ T ++WN ++ Sbjct: 1458 YYSPIRLYIHTLCSNHYLDLFITFIICINVVTMSIEHYDQPQYLEEALKYCNYVFTIFFILEAILKLVAFGIRRFFKDRWNQLDLAIVLLSIMGITLEEIKMNAALPINPTIIRIMRVLRIARVLKLLKMAKGMRALLDTVMQALPQVGNLGLLFMLLFFIYAALGVELFGKLDCIKQPCEGLSRHATFENFGMAFLTLFRVSTGDNWNGIM 1669 HSP 6 Score: 81.2629 bits (199), Expect = 1.113e-14 Identity = 89/303 (29.37%), Postives = 156/303 (51.49%), Query Frame = 1 Query: 4795 YWENYSKWRRTINSVVTSKYFDLAIAGVIGLNVITMATEFHMMPQVLKTALKVFNYFFTSTFVXXXXXXXXXXXXXRYISDKWNQLDMMIVILSIAGVVIDEVESNFMPINPTIMRVMRVLRIARVLKLLKMASGIRALLDTVIQALPQVGNXXXXXXXXXXXXXXXXVELFGRLECSDINPCVGLGRHAHFENFGMAFLTLFRIATGDNWNGIMKDTLREKCISSEDCQRNCCVSAIIAPIYFVIFXXXXXXXXXXXXXXXXXKHLE-ESHKMMCDDYELEREVQRDLDEEAKELAREKQLK 5700 YWE++ R + +V SKYF+ I I +N ++M E H P+ L L++ N FTS FVLE + KLVA G+ YI + +N D +IV++S+ +I + + + V+R R+ RVLKL++ +R L +++++ V +L L + F+ LG+ LFG C + +F++ A +T+F+I T ++WN ++ + + S+ +A +YFV + +VL N++VA+L++ + E D E +R V + +E+ EL R ++LK Sbjct: 643 YWEDF---RDRMKRIVDSKYFNRGIMIAILINTLSMGIEHHEQPKELTDILEISNIVFTSMFVLEMIFKLVAFGIYGYIKNPYNIFDGIIVVISVWE-IIGQADGG--------LSVLRTFRLLRVLKLVRFLPALRRQLVVLMKSMDNVATFCMLLMLFIFTFSILGMHLFGCKFCLKTENGDTIPDRKNFDSLLWAIVTVFQILTQEDWNVVLYNGMAS--------------SSPLASLYFVALMTFGNYVLFNLLVAILVEAFQAEGDANRSDSDEEKRSVDFEEEEKMGEL-RARELK 918 HSP 7 Score: 79.7221 bits (195), Expect = 4.000e-14 Identity = 68/266 (25.56%), Postives = 130/266 (48.87%), Query Frame = 1 Query: 2191 FQRGILIAILINTLSMGIEYHQQPVQLTQT--LEFSNIVFSILFLIEMILKLIGEGILGYIKNGFNLFDGIIVVLGVIELCQQGGTSG-------LSILRTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKF----------------CTIENNKRTCDRKNFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTS----------SWAALYFIALMTFGNYVLFNLLVAILVEGFSSERLDE 2883 F +L+ I +N +++ +E T+ L SN VF+++FL EM +K++ G Y+++ +N+ DG++V + +I++ +SG L +LR R LR L+++ P L+ + +I ++ + + F IF ILG+ LF KF C + N K + NFD+L +++++F + ++ W ++Y+G+ W LYFI+ + ++ + N+ V ++VE F R D+ Sbjct: 1162 FDHVVLVFIFLNCITIALERPNIKPHSTERVFLSISNYVFTVIFLAEMTVKVVALGFYSYLQSTWNILDGMLVFVSLIDILVSLASSGGNRILGILRVLRLLRTLRPLRVISRAPGLKLVVETLITSLRPIGNIVVICWAFFIIFGILGVQLFKGKFYHCEGLDTRNITNKSDCLLANYKWVPRKYNFDNLGQALMSLFVLSCKDGWVNIMYDGLDAVGVDQQPVRNHNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHKCRQDQ 1427 HSP 8 Score: 78.1814 bits (191), Expect = 1.185e-13 Identity = 56/156 (35.90%), Postives = 88/156 (56.41%), Query Frame = 1 Query: 3916 LFFITLNCITLAMERP--SIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKG 4377 + I LNC+TL M +P + S+ + L + F EM+IK+++ G+ G YL WN +D F+V +L+ + GH+ + I R +R LRPL+ I+R P +K++V LL +L +GN++L+C F IFGI+GVQL+ G Sbjct: 1 MLVILLNCVTLGMYQPCEDVACQSEWCIILRAFDDCIFAFFAVEMVIKMMALGIF-GPACYLGDTWNRLDFFIVMAGMLEYSLD---GHNASLSAI----RTVRVLRPLKAINRVPSMKILVTLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAG 148 HSP 9 Score: 55.8398 bits (133), Expect = 6.222e-7 Identity = 33/116 (28.45%), Postives = 60/116 (51.72%), Query Frame = 1 Query: 337 FHIFHQNKHPRDWCLKIITWPWFEQLSMTIIAVNCITLSMYQPCGDQNCETSKCQIMQAFDYIIFAFFTCEMVIKIIAMGFLGDLGYFGDTWNRLDMFIVIVGSIEILPSTGNNIG 684 ++F R C +II+ F+ + + I +NCIT+++ +P + +++ + +Y+ F EM +K++A+GF Y TWN LD +V V I+IL S ++ G Sbjct: 1140 LYMFSPENKFRVICNRIISHRLFDHVVLVFIFLNCITIALERP--NIKPHSTERVFLSISNYVFTVIFLAEMTVKVVALGF---YSYLQSTWNILDGMLVFVSLIDILVSLASSGG 1250 HSP 10 Score: 53.1434 bits (126), Expect = 4.455e-6 Identity = 30/94 (31.91%), Postives = 51/94 (54.26%), Query Frame = 1 Query: 4426 NDCLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFHKCQE 4707 N C N K NFDN+G A +A+F + + +GWV IMY +DA H+ + IYFI +++ +FF++N+ + V+ F + ++ Sbjct: 233 NQCRPGDLNPHKG-AVNFDNIGYAWIAIFQVITLEGWVDIMYYVMDA----------HSFYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQ 315
BLAST of Voltage-dependent T-type calcium channel subunit alpha vs. Ensembl Cavefish
Match: cacna1ha (calcium channel, voltage-dependent, T type, alpha 1H subunit a [Source:ZFIN;Acc:ZDB-GENE-130103-1]) HSP 1 Score: 619.002 bits (1595), Expect = 0.000e+0 Identity = 391/684 (57.16%), Postives = 506/684 (73.98%), Query Frame = 1 Query: 3673 KALEEPDDSNSESQNSSRMNNVEDPDEEDMEAMIC--LSKCCPQPKGIFAKRYYH-SLYVFSVDNQFRQKCQHIVDKKSFDYLVLFFITLNCITLAMERPSIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKFYYCDGPHLQAVKTKNDCLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFHKCQENQ-------XXXXXXXXXXXXXXXXXXXXXHLRAPLYWENYSKWRRTINSVVTSKYFDLAIAGVIGLNVITMATEFHMMPQVLKTALKVFNYFFTSTFVXXXXXXXXXXXXXRYISDKWNQLDMMIVILSIAGVVIDEVESN-FMPINPTIMRVMRVLRIARVLKLLKMASGIRALLDTVIQALPQVGNXXXXXXXXXXXXXXXXVELFGRLECSDINPCVGLGRHAHFENFGMAFLTLFRIATGDNWNGIMKDTLREKCISSEDCQRNCCVSAIIAPIYFVIFXXXXXXXXXXXXXXXXXKHLEESHK------MMCDDYELEREVQRDLDEEAK 5673 +A++ P D +E +N + +EED++ C L + K + K + SLY+FS +N+FR C I+ + FD++VL FI LNCIT+A+ERP+I PHS ER+FL+++NY+FT+IF EM +KV++ G +YL+S WNI+DG LVF+SL+D+ +++ NRI GILRV RLLRTLRPLRVISRAPGLKLVV+TL++SLRPIGNIV+IC FFIIFGILGVQLFKGKFY+C+G + + K+DCL + +W +KYNFDNLGQALM+LFVLS KDGWV IMY G+DAVGV+ QP NHN W L+YFISFLL+V+FFVLNMFVGVVVENFHKC+++Q +E++ R+ KR R E + Y+ YS R I+++ ++ Y DL I +I +NV+TM+ E + PQ L+ ALK NY FT F+LEA+LKLVA G+ R+ D+WNQLD+ IV+LSI G+ ++E++ N +PINPTI+R+MRVLRIARVLKLLKMA G+RALLDTV+QALPQVGNLGLLF LLF+I+AALGVELFG+L+C PC GL RHA FENFGMAFLTLFR++TGDNWNGIMKDTLRE CI +++C +++P+YFV FVLMAQFVLVNVVVAVLMKHLEES+K M D E+++E+Q D+ + Sbjct: 1077 RAMQLPTDLPAE------LNREDSANEEDLDDSFCCRLRRMLNAYKPQWCKDHEDWSLYMFSPENKFRVICNRIISHRLFDHVVLVFIFLNCITIALERPNIKPHSTERVFLSISNYVFTVIFLAEMTVKVVALGFY----SYLQSTWNILDGMLVFVSLIDILVSLASSGGNRILGILRVLRLLRTLRPLRVISRAPGLKLVVETLITSLRPIGNIVVICWAFFIIFGILGVQLFKGKFYHCEGLDTRNITNKSDCL-LANYKWVPRKYNFDNLGQALMSLFVLSCKDGWVNIMYDGLDAVGVDQQPVRNHNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHKCRQDQEEEEARLREEKRRRQQEKRRRSKENYGSEAQKIPYYAYYSPIRLYIHTLCSNHYLDLFITFIICINVVTMSIEHYDQPQYLEEALKYCNYVFTIFFILEAILKLVAFGIRRFFKDRWNQLDLAIVLLSIMGITLEEIKMNAALPINPTIIRIMRVLRIARVLKLLKMAKGMRALLDTVMQALPQVGNLGLLFMLLFFIYAALGVELFGKLDCIK-QPCEGLSRHATFENFGMAFLTLFRVSTGDNWNGIMKDTLRE-CIPADNC---LSYLPLVSPLYFVTFVLMAQFVLVNVVVAVLMKHLEESNKEAKEEAEMDSDTEMDKEIQNATDDSGE 1744 HSP 2 Score: 352.829 bits (904), Expect = 1.760e-97 Identity = 211/393 (53.69%), Postives = 282/393 (71.76%), Query Frame = 1 Query: 418 MTIIAVNCITLSMYQPCGDQNCETSKCQIMQAFDYIIFAFFTCEMVIKIIAMGFLGDLGYFGDTWNRLDMFIVIVGSIEILPSTGNNIGLTAIRTIRVLRPLRAINRIPSMRIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQMWQGVLRNRCYLNLNESFRHPGLNLSSFYQINRTLFLNAVDKDFICSTDKNNGILKCSDIPPSIMLLSNNSLQICKQPARPFTDNLPTKHSCVNWNQYYTDCQPGEKNPYEGAINFDNIGFAWVAIFQVISMESWVDIMYYVQDAHSFWDWIYFVALIIIGSFFMINLCLVVIASQFSETKRRETERMWIERRRFNSSNCSSISKDEPQTCYLEXXXXXXXXXXXXYRRIVKLYNQIQIRHSKTAQGN 1596 M +I +NC+TL MYQPC D C++ C I++AFD IFAFF EMVIK++A+G G Y GDTWNRLD FIV+ G +E G+N L+AIRT+RVLRPL+AINR+PSM+ILV LLLDTLPMLGNVLLLCFFVFFIFGI+GVQ+W G+LRNRC++ N + + L++S +Y + D FICS++K NG+ +C ++PP L+ N +T + P +SCVNWNQYY C+PG+ NP++GA+NFDNIG+AW+AIFQVI++E WVDIMYYV DAHSF+++IYF+ LII+GSFFMINLCLVVIA+QFSETK+R + M +R + S++ + S EP +CY E+++ I+ + K+ RR +LY+ Q + K N Sbjct: 1 MLVILLNCVTLGMYQPCEDVACQSEWCIILRAFDDCIFAFFAVEMVIKMMALGIFGPACYLGDTWNRLDFFIVMAGMLE-YSLDGHNASLSAIRTVRVLRPLKAINRVPSMKILVTLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAGLLRNRCFMKENFTDIY-NLSMSQYYMDE-----DGEDNPFICSSEKENGMRRCRNVPP---LMENGFNCTLNASFSHYTYSDP--NSCVNWNQYYNQCRPGDLNPHKGAVNFDNIGYAWIAIFQVITLEGWVDIMYYVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQRVNKLMKDQRVCYQSNDSTLASYSEPGSCYEEMLRYISHLYRKVKRRTSRLYHGWQSKRRKKINPN 381 HSP 3 Score: 326.635 bits (836), Expect = 2.153e-89 Identity = 183/320 (57.19%), Postives = 234/320 (73.12%), Query Frame = 1 Query: 2155 QQKIKTLVNDVKFQRGILIAILINTLSMGIEYHQQPVQLTQTLEFSNIVFSILFLIEMILKLIGEGILGYIKNGFNLFDGIIVVLGVIELCQQGGTSGLSILRTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKFC-TIENNKRTCDRKNFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTSSWAALYFIALMTFGNYVLFNLLVAILVEGFSSE------RLDEQKLLHNYRQSLKKRRANNKQLRIMQHQSENLVLLTNSIQKDQTGENQKISSQPPVIIHTAATPMPTPRSS 3093 + ++K +V+ F RGI+IAILINTLSMGIE+H+QP +LT LE SNIVF+ +F++EMI KL+ GI GYIKN +N+FDGIIVV+ V E+ Q GLS+LRTFRLLR+LKLVRF+PALR+QL V+++++DNVATF LL+LFIF FSILGM LFGCKFC EN DRKNFDSLLW+IVTVFQILTQEDWN VLYNGM +S A+LYF+ALMTFGNYVLFNLLVAILVE F +E DE+K ++ + K ++L++ ++++ + + G + PP+I+ TAATPMPTP+SS Sbjct: 636 RDRMKRIVDSKYFNRGIMIAILINTLSMGIEHHEQPKELTDILEISNIVFTSMFVLEMIFKLVAFGIYGYIKNPYNIFDGIIVVISVWEIIGQA-DGGLSVLRTFRLLRVLKLVRFLPALRRQLVVLMKSMDNVATFCMLLMLFIFTFSILGMHLFGCKFCLKTENGDTIPDRKNFDSLLWAIVTVFQILTQEDWNVVLYNGMASSSPLASLYFVALMTFGNYVLFNLLVAILVEAFQAEGDANRSDSDEEKRSVDFEEEEKMGELRARELKMYS------LMMSANGHVESRG-----NLPPPIIMRTAATPMPTPKSS 943 HSP 4 Score: 115.546 bits (288), Expect = 5.505e-25 Identity = 75/293 (25.60%), Postives = 143/293 (48.81%), Query Frame = 1 Query: 3817 KRYYHSLYVFSVDNQFRQKCQHIVDKKSFDYLVLFFITLNCITLAMERPSIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKFYYCDGPHLQAVKTKNDCLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFH 4695 KR +++ FR + + IVD K F+ ++ I +N +++ +E P + L ++N +FT +F EMI K+++ G+ Y+K+ +NI DG +V IS+ + ++G ++ +LR FRLLR L+ +R + P L+ + L+ S+ + ++ F F ILG+ LF KF CLK + + NFD+L A++ +F + +++ W ++Y G+ + + A +YF++ + + + N+ V ++VE F Sbjct: 620 KRLCERIHMARYWEDFRDRMKRIVDSKYFNRGIMIAILINTLSMGIEHHEQPKELTD--ILEISNIVFTSMFVLEMIFKLVAFGIY----GYIKNPYNIFDGIIVVISVWE-----IIGQADGGLSVLRTFRLLRVLKLVRFL---PALRRQLVVLMKSMDNVATFCMLLMLFIFTFSILGMHLFGCKF----------------CLKTENGDTIPDRKNFDSLLWAIVTVFQILTQEDWNVVLYNGM----------ASSSPLASLYFVALMTFGNYVLFNLLVAILVEAFQ 872 HSP 5 Score: 90.1225 bits (222), Expect = 2.914e-17 Identity = 61/224 (27.23%), Postives = 113/224 (50.45%), Query Frame = 1 Query: 2104 FNKNQNKTKRKNYLSICQQKIKTLVNDVKFQRGILIAILINTLSMGIEYHQQPVQLTQTLEFSNIVFSILFLIEMILKLIGEGILGYIKNGFNLFDGIIVVLGVIELCQQG---------GTSGLSILRTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKFCTIENNKRTCDRKNFDSLLWSIVTVFQILTQEDWNTVL 2748 + K Y S + I TL ++ I I IN ++M IE++ QP L + L++ N VF+I F++E ILKL+ GI + K+ +N D IV+L ++ + + + + I+R R+ R+LKL++ +R L +++ + V L +L FI++ LG+ LFG C + + F++ + +T+F++ T ++WN ++ Sbjct: 1441 YGSEAQKIPYYAYYSPIRLYIHTLCSNHYLDLFITFIICINVVTMSIEHYDQPQYLEEALKYCNYVFTIFFILEAILKLVAFGIRRFFKDRWNQLDLAIVLLSIMGITLEEIKMNAALPINPTIIRIMRVLRIARVLKLLKMAKGMRALLDTVMQALPQVGNLGLLFMLLFFIYAALGVELFGKLDCIKQPCEGLSRHATFENFGMAFLTLFRVSTGDNWNGIM 1664 HSP 6 Score: 80.8777 bits (198), Expect = 1.585e-14 Identity = 89/303 (29.37%), Postives = 156/303 (51.49%), Query Frame = 1 Query: 4795 YWENYSKWRRTINSVVTSKYFDLAIAGVIGLNVITMATEFHMMPQVLKTALKVFNYFFTSTFVXXXXXXXXXXXXXRYISDKWNQLDMMIVILSIAGVVIDEVESNFMPINPTIMRVMRVLRIARVLKLLKMASGIRALLDTVIQALPQVGNXXXXXXXXXXXXXXXXVELFGRLECSDINPCVGLGRHAHFENFGMAFLTLFRIATGDNWNGIMKDTLREKCISSEDCQRNCCVSAIIAPIYFVIFXXXXXXXXXXXXXXXXXKHLE-ESHKMMCDDYELEREVQRDLDEEAKELAREKQLK 5700 YWE++ R + +V SKYF+ I I +N ++M E H P+ L L++ N FTS FVLE + KLVA G+ YI + +N D +IV++S+ +I + + + V+R R+ RVLKL++ +R L +++++ V +L L + F+ LG+ LFG C + +F++ A +T+F+I T ++WN ++ + + S+ +A +YFV + +VL N++VA+L++ + E D E +R V + +E+ EL R ++LK Sbjct: 631 YWEDF---RDRMKRIVDSKYFNRGIMIAILINTLSMGIEHHEQPKELTDILEISNIVFTSMFVLEMIFKLVAFGIYGYIKNPYNIFDGIIVVISVWE-IIGQADGG--------LSVLRTFRLLRVLKLVRFLPALRRQLVVLMKSMDNVATFCMLLMLFIFTFSILGMHLFGCKFCLKTENGDTIPDRKNFDSLLWAIVTVFQILTQEDWNVVLYNGMAS--------------SSPLASLYFVALMTFGNYVLFNLLVAILVEAFQAEGDANRSDSDEEKRSVDFEEEEKMGEL-RARELK 906 HSP 7 Score: 80.1073 bits (196), Expect = 2.808e-14 Identity = 68/266 (25.56%), Postives = 130/266 (48.87%), Query Frame = 1 Query: 2191 FQRGILIAILINTLSMGIEYHQQPVQLTQT--LEFSNIVFSILFLIEMILKLIGEGILGYIKNGFNLFDGIIVVLGVIELCQQGGTSG-------LSILRTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKF----------------CTIENNKRTCDRKNFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTS----------SWAALYFIALMTFGNYVLFNLLVAILVEGFSSERLDE 2883 F +L+ I +N +++ +E T+ L SN VF+++FL EM +K++ G Y+++ +N+ DG++V + +I++ +SG L +LR R LR L+++ P L+ + +I ++ + + F IF ILG+ LF KF C + N K + NFD+L +++++F + ++ W ++Y+G+ W LYFI+ + ++ + N+ V ++VE F R D+ Sbjct: 1150 FDHVVLVFIFLNCITIALERPNIKPHSTERVFLSISNYVFTVIFLAEMTVKVVALGFYSYLQSTWNILDGMLVFVSLIDILVSLASSGGNRILGILRVLRLLRTLRPLRVISRAPGLKLVVETLITSLRPIGNIVVICWAFFIIFGILGVQLFKGKFYHCEGLDTRNITNKSDCLLANYKWVPRKYNFDNLGQALMSLFVLSCKDGWVNIMYDGLDAVGVDQQPVRNHNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHKCRQDQ 1415 HSP 8 Score: 78.1814 bits (191), Expect = 1.025e-13 Identity = 56/156 (35.90%), Postives = 88/156 (56.41%), Query Frame = 1 Query: 3916 LFFITLNCITLAMERP--SIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKG 4377 + I LNC+TL M +P + S+ + L + F EM+IK+++ G+ G YL WN +D F+V +L+ + GH+ + I R +R LRPL+ I+R P +K++V LL +L +GN++L+C F IFGI+GVQL+ G Sbjct: 1 MLVILLNCVTLGMYQPCEDVACQSEWCIILRAFDDCIFAFFAVEMVIKMMALGIF-GPACYLGDTWNRLDFFIVMAGMLEYSLD---GHNASLSAI----RTVRVLRPLKAINRVPSMKILVTLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAG 148 HSP 9 Score: 56.225 bits (134), Expect = 4.561e-7 Identity = 33/116 (28.45%), Postives = 60/116 (51.72%), Query Frame = 1 Query: 337 FHIFHQNKHPRDWCLKIITWPWFEQLSMTIIAVNCITLSMYQPCGDQNCETSKCQIMQAFDYIIFAFFTCEMVIKIIAMGFLGDLGYFGDTWNRLDMFIVIVGSIEILPSTGNNIG 684 ++F R C +II+ F+ + + I +NCIT+++ +P + +++ + +Y+ F EM +K++A+GF Y TWN LD +V V I+IL S ++ G Sbjct: 1128 LYMFSPENKFRVICNRIISHRLFDHVVLVFIFLNCITIALERP--NIKPHSTERVFLSISNYVFTVIFLAEMTVKVVALGF---YSYLQSTWNILDGMLVFVSLIDILVSLASSGG 1238 HSP 10 Score: 53.9138 bits (128), Expect = 2.533e-6 Identity = 30/94 (31.91%), Postives = 51/94 (54.26%), Query Frame = 1 Query: 4426 NDCLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFHKCQE 4707 N C N K NFDN+G A +A+F + + +GWV IMY +DA H+ + IYFI +++ +FF++N+ + V+ F + ++ Sbjct: 233 NQCRPGDLNPHKG-AVNFDNIGYAWIAIFQVITLEGWVDIMYYVMDA----------HSFYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQ 315 HSP 11 Score: 52.373 bits (124), Expect = 7.062e-6 Identity = 25/80 (31.25%), Postives = 47/80 (58.75%), Query Frame = 1 Query: 1195 NFDNIGFAWVAIFQVISMESWVDIMYYVQDA----------HSFWDWIYFVALIIIGSFFMINLCLVVIASQFSETKRRE 1404 NFDN+G A +++F + + WV+IMY DA H+ W +YF++ ++I SFF++N+ + V+ F + ++ + Sbjct: 1336 NFDNLGQALMSLFVLSCKDGWVNIMYDGLDAVGVDQQPVRNHNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHKCRQDQ 1415
BLAST of Voltage-dependent T-type calcium channel subunit alpha vs. Ensembl Cavefish
Match: cacna1ib (calcium voltage-gated channel subunit alpha1 Ib [Source:ZFIN;Acc:ZDB-GENE-120215-18]) HSP 1 Score: 603.594 bits (1555), Expect = 8.855e-180 Identity = 367/613 (59.87%), Postives = 471/613 (76.84%), Query Frame = 1 Query: 3832 SLYVFSVDNQFRQKCQHIVDKKSFDYLVLFFITLNCITLAMERPSIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKFYYCDGPHLQAVKTKNDCLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFHKCQENQXXXXXXXXXXXXXXXXXXXXXHLRAPLYWENYSKWRRTINSVVTSKYFDLAIAGVIGLNVITMATEFHMMPQVLKTALKVFNYFFTSTFVXXXXXXXXXXXXXRYISDKWNQLDMMIVILSIAGVVIDEVESNF-MPINPTIMRVMRVLRIARVLKLLKMASGIRALLDTVIQALPQV-GNXXXXXXXXXXXXXXXXVELFGRLECSDINPCVGLGRHAHFENFGMAFLTLFRIATGDNWNGIMKDTLREKCISSEDCQRNCCVSAIIAPIYFVIFXXXXXXXXXXXXXXXXXKHLEESHKMMCDDYELEREVQRDLDE 5664 S+Y+FS N+FR CQ I+ K FDY+VL FI LNCIT+A+ERP I S ER+FLT++NYIFT IF EM +KV+S GL +G++AYL+S WNI+DGFLVF+SL+D+ +++ G +I G+LRV RLLRTLRPLRVISRAPGLKLVV+TL++SL+PIGNIVLICC FFIIFGILGVQLFKGKFYYC G ++ + K+DCL ++ +W + KYNFDNLGQALM+LFVL+SKDGWV IMY G+DAVG++ QP N+N W L+YFISFLL+V+FFVLNMFVGVVVENFHKC+++QE EE RR KR RR+EKKR+ + Y+ YS R I+S TS Y DL I +I +NV+TM+ E + P+ LK NYFF+STFV+EA+LKL+A G R+ D+WNQLD+ IV+LS+ G+ ++E+E N +PINPTI+R+MRVLRIARVLKLLKMA+G+RALLDTV+QALPQV L L +++ + L L C+ +PC G+ RHA FENFGMAFLTLF+++TGDNWNGIMKDTLRE C + N + I+P+YFV FVL AQFVL+NVVVAVLMKHL++S+K +D E++ E++ +L + Sbjct: 1061 SVYLFSPQNKFRLTCQKIIAHKLFDYVVLAFIFLNCITVALERPKIHQGSLERVFLTISNYIFTAIFVAEMTVKVVSMGLYLGERAYLRSSWNILDGFLVFVSLIDIVVSMAGG--AKILGVLRVLRLLRTLRPLRVISRAPGLKLVVETLITSLKPIGNIVLICCAFFIIFGILGVQLFKGKFYYCVGLDVKNITNKSDCLS-AKYKWVHHKYNFDNLGQALMSLFVLASKDGWVNIMYHGLDAVGIDQQPVINNNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHKCRQHQEVEEAKRREEKRLRRMEKKRRKAQKLPYYAGYSHIRLMIHSFCTSHYLDLFITLIICINVVTMSLEHYDQPK----GLKYCNYFFSSTFVVEAMLKLIAFGFRRFFKDRWNQLDLAIVLLSVMGITLEEIEINASLPINPTIIRIMRVLRIARVLKLLKMATGMRALLDTVVQALPQVHAGLALFPSFIYHHLTSSFFSLSLYLVCNADHPCEGMSRHATFENFGMAFLTLFQVSTGDNWNGIMKDTLRE-CPHGNNHSCNASLQ-FISPMYFVSFVLTAQFVLINVVVAVLMKHLDDSNKEAQEDAEMDAEIELELAQ 1664 HSP 2 Score: 305.449 bits (781), Expect = 6.155e-83 Identity = 211/464 (45.47%), Postives = 275/464 (59.27%), Query Frame = 1 Query: 235 LTDKSKADHCQQETDGTPINPNESLI-YHGFYATVFHIFHQNKHPRDWCLKIITWP------WFEQLSMTIIAVNCITLSMYQPCGDQNCETSKCQIMQAFDYIIFAFFTCEMVIKIIAMGFLGDLGYFGDTWNRLDMFIVIVGSIEILPSTGNNIGLTAIRTIRVLRPLRAINRIPSMRIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQMWQGVLRNRCYLNLNESFRHPGLNLSSFYQINRTLFLNAVDKDFICSTDKNNGILKCSDIPPSIMLLSNNSL--------QICKQPARPF--TDNLPTKHSCVNWNQYYTDCQPGEKNPYEGAINFDNIGFAWVAIFQVISMESWVDIMYYVQDAHSFWDWIYFVALIIIGSFFMINLCLVVIASQFSETKRRETERMWIERRR-FNSSNCSSISKDEPQTCYLEXXXXXXXXXXXXYRRIVKLYNQIQIR 1572 L + +A H ++ D + ++ Y VF Q PR WC+++++ P WFE++SM +I +NC+TL MYQPC + +C + +CQI+QAFD +I+ FF EMV+K++ +G G Y GDTWNRLD FIV+ G +E NI TAIRT+RVLRPL+AINR+PSMRILV LLLDTLPMLGNVLLLCFFVFFIFGIIGVQ+W G+LRNRCY N + G+ L + Y ++ FICS ++NGI+ CSDIP N L Q A P CVNWN+YYT C G KNP++GAINFDNIG+AW+ IFQV + IYF ++GSFFMINLCLVVIA+QFSETK+RE + M +R +SS +S++ EP CY E+ +L I+ K RR L+ + R Sbjct: 29 LEPEERAGHVEEVDDDVSSELSGLVVPYPELAPVVFFCLKQTTFPRSWCIRLVSSPYPLLFTWFERVSMMVIILNCVTLGMYQPCENIDCSSQRCQILQAFDAMIYIFFAVEMVVKMVGLGIFGRRCYLGDTWNRLDFFIVMAGVVEYSLDL-QNINFTAIRTVRVLRPLKAINRVPSMRILVNLLLDTLPMLGNVLLLCFFVFFIFGIIGVQLWAGLLRNRCYPEDNFTLSS-GMALPTPYYSPD----EEDERPFICSLPQDNGIMSCSDIPVRREGGRNCCLDVEDALHWQALGMAAEPIFNASAGAVPGLCVNWNRYYTRCLTGYKNPHKGAINFDNIGYAWIVIFQVFT--------------------IYFFFYQMVGSFFMINLCLVVIATQFSETKQREHQLMQEQRAACLSSSTLASLA--EPGDCYEELFQLACHILRKARRRSAALFRAFRRR 464 HSP 3 Score: 292.352 bits (747), Expect = 5.935e-79 Identity = 164/267 (61.42%), Postives = 199/267 (74.53%), Query Frame = 1 Query: 2107 NKNQNKTKRKNYLSICQQKIKTL-----------VNDVKFQRGILIAILINTLSMGIEYHQQPVQLTQTLEFSNIVFSILFLIEMILKLIGEGILGYIKNGFNLFDGIIVVLGVIELCQQGGTSGLSILRTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKFCTIENNKRTC-DRKNFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTSSWAALYFIALMTFGNYVLFNLLVAILVEGFSSE 2871 ++ ++++ K C+ K K L V F RGI+IAILINT+SMGIE+H+QP +LT LE NIVF+ +F +EMILKL G Y++N +N+FDGIIV++ V E+ Q GLS+LRTFRLLR+LKLVRFMPALR+QL V+++T+DNVATF LL+LFIFIFSILGM +FGCKF + T DRKNFDSLLW+IVTVFQILTQEDWN VLYNGM TS AALYF+ALMTFGNYVLFNLLVAILVEGF +E Sbjct: 538 DEQADQSEEKKEKGACKGKCKELWIEMRIKLWGIVESKYFNRGIMIAILINTISMGIEHHEQPEELTNVLEICNIVFTSMFALEMILKLTAFGCFNYLRNPYNIFDGIIVIISVCEIVGQS-DGGLSVLRTFRLLRVLKLVRFMPALRRQLVVLMKTMDNVATFCMLLMLFIFIFSILGMHIFGCKFSLKTDAGDTVPDRKNFDSLLWAIVTVFQILTQEDWNVVLYNGMASTSPLAALYFVALMTFGNYVLFNLLVAILVEGFQAE 803 HSP 4 Score: 106.686 bits (265), Expect = 2.268e-22 Identity = 86/342 (25.15%), Postives = 154/342 (45.03%), Query Frame = 1 Query: 3676 ALEEPDDSNSESQNSSRMNNVEDPDEEDMEAMICLSKCCPQPKGIFAKRYYHSLYVFSVDNQFRQKCQHIVDKKSFDYLVLFFITLNCITLAMERPSIPPHSKERL--FLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKFYYCDGPHLQAVKTKNDCLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFH 4695 A EE +D + + + D EE E C KC L++ + R K IV+ K F+ ++ I +N I++ +E P E L L + N +FT +F EMI+K+ + G YL++ +NI DG +V IS+ + ++G S+ +LR FRLLR L+ +R + P L+ + L+ ++ + ++ F IF ILG+ +F KF LK + + NFD+L A++ +F + +++ W ++Y G+ + + A +YF++ + + + N+ V ++VE F Sbjct: 525 ASEEAEDGAEQ-----KTDEQADQSEEKKEKGACKGKC-------------KELWI-----EMRIKLWGIVESKYFNRGIMIAILINTISMGIEHHEQP----EELTNVLEICNIVFTSMFALEMILKLTAFGCF----NYLRNPYNIFDGIIVIISVCE-----IVGQSDGGLSVLRTFRLLRVLKLVRFM---PALRRQLVVLMKTMDNVATFCMLLMLFIFIFSILGMHIFGCKF----------------SLKTDAGDTVPDRKNFDSLLWAIVTVFQILTQEDWNVVLYNGMAST----------SPLAALYFVALMTFGNYVLFNLLVAILVEGFQ 801 HSP 5 Score: 76.2554 bits (186), Expect = 3.906e-13 Identity = 65/254 (25.59%), Postives = 121/254 (47.64%), Query Frame = 1 Query: 2203 ILIAILINTLSMGIEYHQQPVQLTQTLEFSNIVFSILFLIEMILKLIGEGILGYIKNGFNLFDGIIVVLGVIELCQQG---------GTSGLSILRTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKFCTIENNKRTCD----RKNFDSLLWSIVTVFQILTQEDWNTVLYNGMTRT------SSWAALYFIALMTF------GNYVLFNLLVAILVEGFSSERLDEQK 2889 I + I IN ++M +E++ QP + L++ N FS F++E +LKLI G + K+ +N D IV+L V+ + + + + I+R R+ R+LKL++ +R L +++ + V AL FI+ S F + N C+ F++ + +T+FQ+ T ++WN ++ + + S A+L FI+ M F +VL N++VA+L++ + Q+ Sbjct: 1403 ITLIICINVVTMSLEHYDQP----KGLKYCNYFFSSTFVVEAMLKLIAFGFRRFFKDRWNQLDLAIVLLSVMGITLEEIEINASLPINPTIIRIMRVLRIARVLKLLKMATGMRALLDTVVQALPQVHAGLALFPSFIYHHLTS--SFFSLSLYLVCNADHPCEGMSRHATFENFGMAFLTLFQVSTGDNWNGIMKDTLRECPHGNNHSCNASLQFISPMYFVSFVLTAQFVLINVVVAVLMKHLDDSNKEAQE 1650 HSP 6 Score: 75.485 bits (184), Expect = 7.278e-13 Identity = 55/161 (34.16%), Postives = 92/161 (57.14%), Query Frame = 1 Query: 3901 FDYLVLFFITLNCITLAMERP--SIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKG 4377 F+ + + I LNC+TL M +P +I S+ L + + I F EM++K++ G+ G + YL WN +D F+V +++ + + N F +R +R LRPL+ I+R P ++++V LL +L +GN++L+C F IFGI+GVQL+ G Sbjct: 92 FERVSMMVIILNCVTLGMYQPCENIDCSSQRCQILQAFDAMIYIFFAVEMVVKMVGLGIF-GRRCYLGDTWNRLDFFIVMAGVVEYSLDL----QNINFTAIRT---VRVLRPLKAINRVPSMRILVNLLLDTLPMLGNVLLLCFFVFFIFGIIGVQLWAG 244 HSP 7 Score: 71.2478 bits (173), Expect = 1.477e-11 Identity = 66/222 (29.73%), Postives = 113/222 (50.90%), Query Frame = 1 Query: 4801 ENYSKWRRTINSVVTSKYFDLAIAGVIGLNVITMATEFHMMPQVLKTALKVFNYFFTSTFVXXXXXXXXXXXXXRYISDKWNQLDMMIVILSIAGVVIDEVESNFMPINPTIMRVMRVLRIARVLKLLKMASGIRALLDTVIQALPQVGNXXXXXXXXXXXXXXXXVELFG-----RLECSDINPCVGLGRHAHFENFGMAFLTLFRIATGDNWNGIMKDTL 5451 E + + R + +V SKYF+ I I +N I+M E H P+ L L++ N FTS F LE +LKL A G Y+ + +N D +IVI+S+ +V + V+R R+ RVLKL++ +R L +++ + V +L L +IF+ LG+ +FG + + D P +F++ A +T+F+I T ++WN ++ + + Sbjct: 559 ELWIEMRIKLWGIVESKYFNRGIMIAILINTISMGIEHHEQPEELTNVLEICNIVFTSMFALEMILKLTAFGCFNYLRNPYNIFDGIIVIISVCEIVGQSDGG---------LSVLRTFRLLRVLKLVRFMPALRRQLVVLMKTMDNVATFCMLLMLFIFIFSILGMHIFGCKFSLKTDAGDTVP-----DRKNFDSLLWAIVTVFQILTQEDWNVVLYNGM 766 HSP 8 Score: 64.6994 bits (156), Expect = 1.544e-9 Identity = 87/350 (24.86%), Postives = 167/350 (47.71%), Query Frame = 1 Query: 1981 PLLTSKDKVYPQSVASR------SSSINSCAYQIPRLTDSYSKHRRPFNKNQNKTKRKNYLSICQQKIK----TLVNDVKFQRGILIAILINTLSMGIE---YHQQPVQLTQTLEFSNIVFSILFLIEMILKLIGEGI-LG---YIKNGFNLFDGIIVVLGVIELC--QQGGTS---GLSILRTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKF--CT---IEN--NKRTC---------DRKNFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTS----------SWAALYFIALMTFGNYVLFNLLVAILVEGFSSERLDEQ 2886 PLL+ +VYPQ A + + S ++I ++ + Y RP + + + YL Q K + ++ F +L I +N +++ +E HQ ++ L SN +F+ +F+ EM +K++ G+ LG Y+++ +N+ DG +V + +I++ GG L +LR R LR L+++ P L+ + +I ++ + + F IF ILG+ LF KF C ++N NK C + NFD+L +++++F + +++ W ++Y+G+ W LYFI+ + ++ + N+ V ++VE F R ++ Sbjct: 1012 PLLS---EVYPQLNARKDRPHLDEETDYSLCFRIQKMMEVY----RP-DWCETRENWSVYLFSPQNKFRLTCQKIIAHKLFDYVVLAFIFLNCITVALERPKIHQGSLERV-FLTISNYIFTAIFVAEMTVKVVSMGLYLGERAYLRSSWNILDGFLVFVSLIDIVVSMAGGAKILGVLRVLRLLRTLRPLRVISRAPGLKLVVETLITSLKPIGNIVLICCAFFIIFGILGVQLFKGKFYYCVGLDVKNITNKSDCLSAKYKWVHHKYNFDNLGQALMSLFVLASKDGWVNIMYHGLDAVGIDQQPVINNNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHKCRQHQE 1352 HSP 9 Score: 61.6178 bits (148), Expect = 1.050e-8 Identity = 39/117 (33.33%), Postives = 63/117 (53.85%), Query Frame = 1 Query: 331 TVFHIFHQNKHPRDWCLKIITWPWFEQLSMTIIAVNCITLSMYQPCGDQNCETSKCQIMQAFDYIIFAFFTCEMVIKIIAMG-FLGDLGYFGDTWNRLDMFIVIVGSIEILPSTGNN 678 +V+ QNK R C KII F+ + + I +NCIT+++ +P Q + + + +YI A F EM +K+++MG +LG+ Y +WN LD F+V V I+I+ S Sbjct: 1061 SVYLFSPQNKF-RLTCQKIIAHKLFDYVVLAFIFLNCITVALERPKIHQG--SLERVFLTISNYIFTAIFVAEMTVKVVSMGLYLGERAYLRSSWNILDGFLVFVSLIDIVVSMAGG 1174 HSP 10 Score: 58.9214 bits (141), Expect = 7.200e-8 Identity = 37/129 (28.68%), Postives = 71/129 (55.04%), Query Frame = 1 Query: 2191 FQRGILIAILINTLSMGIEYHQQPV-------QLTQTLEFSNIVFSILFLIEMILKLIGEGILG---YIKNGFNLFDGIIVVLGVIELCQQGGTSGLSILRTFRLLRILKLVRFMPALRQQLFVMIRTI 2547 F+R ++ I++N +++G+ QP Q Q L+ + + I F +EM++K++G GI G Y+ + +N D IV+ GV+E + +RT R+LR LK + +P++R + +++ T+ Sbjct: 92 FERVSMMVIILNCVTLGM---YQPCENIDCSSQRCQILQAFDAMIYIFFAVEMVVKMVGLGIFGRRCYLGDTWNRLDFFIVMAGVVEYSLDLQNINFTAIRTVRVLRPLKAINRVPSMRILVNLLLDTL 217 HSP 11 Score: 54.6842 bits (130), Expect = 1.460e-6 Identity = 27/95 (28.42%), Postives = 51/95 (53.68%), Query Frame = 1 Query: 1150 TDCQPGEKNPYEGAINFDNIGFAWVAIFQVISMESWVDIMYYVQDAHSF----------WDWIYFVALIIIGSFFMINLCLVVIASQFSETKRRE 1404 +DC + NFDN+G A +++F + S + WV+IMY+ DA W +YF++ ++I SFF++N+ + V+ F + ++ + Sbjct: 1257 SDCLSAKYKWVHHKYNFDNLGQALMSLFVLASKDGWVNIMYHGLDAVGIDQQPVINNNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHKCRQHQ 1351
BLAST of Voltage-dependent T-type calcium channel subunit alpha vs. Ensembl Cavefish
Match: ENSAMXT00000033959.1 (pep primary_assembly:Astyanax_mexicanus-2.0:4:2732409:2930308:1 gene:ENSAMXG00000029856.1 transcript:ENSAMXT00000033959.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 292.352 bits (747), Expect = 2.616e-87 Identity = 191/368 (51.90%), Postives = 247/368 (67.12%), Query Frame = 1 Query: 244 KSKADHCQQET--DGTPINPNESLIYHGFYATVFHIFHQNKHPRDWCLKIIT--WPWFEQLSMTIIAVNCITLSMYQPCGDQNCETSKCQIMQAFDYIIFAFFTCEMVIKIIAMGFLGDLGYFGDTWNRLDMFIVIVGSIEILPSTGNNIGLTAIRTIRVLRPLRAINRIPSMRIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQMWQGVLRNRCYLNLNESFRHP-GLNLSSFYQINRTLFLNAVDKDFICSTDKNNGILKCSDIPPSIMLLSNNSLQICKQPARPFTDNLPTKHSCVNWNQYYTDCQPGEKNPYEGAINFDNIGFAWVAIFQVISMESWVDIMYYVQDAHSFWDWIYFVALIII 1332 +H +QE G +E+L Y VF Q PR WCLK++ +P+ M +I +NC+TL M+ PC D +C++ +C+I++ FD IFAFF EMVIK++A+G G Y GDTWNRLD FIV+ G +E + N+ +A+RT+RVLRPLRAINR+PSMRILV LLLDTLPMLGNVLLLCFFVFFIFGI+GVQ+W G+LRNRC+L E+F P L+L ++Y N + FICS + NG+ +CS IP MLL A TDN +CVNWNQYYT+C GE NP++GAINFDNIG+AW+AIFQVI++E WVDIMY+V DAHSF+++IYF+ LII+ Sbjct: 34 SGGGEHAEQEGAEQGAERRESEALPYPSLAPVVFFYLKQTTRPRSWCLKMVCNPYPFIPNPDMLVILLNCVTLGMFHPCEDSDCDSERCKILEDFDDFIFAFFAIEMVIKMVALGIFGKKCYLGDTWNRLDFFIVLAGMLEYSLNL-QNVSFSAVRTVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAGLLRNRCFLP--ENFSLPQTLDLHTYYHTE-----NDDESPFICSQPRENGMRQCSSIP---MLLEETVQCHLDMGAYNTTDN----TTCVNWNQYYTNCSAGEVNPFKGAINFDNIGYAWIAIFQVITLEGWVDIMYFVMDAHSFYNFIYFILLIIV 386 HSP 2 Score: 69.707 bits (169), Expect = 1.208e-11 Identity = 55/156 (35.26%), Postives = 85/156 (54.49%), Query Frame = 1 Query: 3916 LFFITLNCITLAMERPSIPPH--SKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKG 4377 + I LNC+TL M P S+ L + F EM+IK+++ G+ G + YL WN +D F+V +L+ + + N F +R +R LRPLR I+R P ++++V LL +L +GN++L+C F IFGI+GVQL+ G Sbjct: 96 MLVILLNCVTLGMFHPCEDSDCDSERCKILEDFDDFIFAFFAIEMVIKMVALGIF-GKKCYLGDTWNRLDFFIVLAGMLEYSLNL----QNVSFSAVRT---VRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAG 243
BLAST of Voltage-dependent T-type calcium channel subunit alpha vs. Ensembl Cavefish
Match: ENSAMXT00000056794.1 (pep primary_assembly:Astyanax_mexicanus-2.0:2:27265512:27410284:-1 gene:ENSAMXG00000029376.1 transcript:ENSAMXT00000056794.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 277.715 bits (709), Expect = 1.865e-82 Identity = 173/334 (51.80%), Postives = 226/334 (67.66%), Query Frame = 1 Query: 331 TVFHIFHQNKHPRDWCLKIITWPWFEQLSMTIIAVNCITLSMYQPCGDQNCETSKCQIMQAFDYIIFAFFTCEMVIKIIAMGFLGDLGYFGDTWNRLDMFIVIVGSIEILPSTGNNIGLTAIRTIRVLRPLRAINRIPSMRIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQMWQGVLRNRCYLNLNESFRHPGLNLSSFYQINRTLFLNAVDKDFICSTDKNNGILKCSDIPPSIMLLSNNSLQICKQPARPFTDNLPTKHSCVNWNQYYTDCQPGEKNPYEGAINFDNIGFAWVAIFQVISMESWVDIMYYVQDAHSFWDWIYFVALIII 1332 VF Q PR+WC+++ ++S+ +I +NC+TL MYQPC + +C + +CQI+QAFD I+ FF EMV+K++A+G G Y GDTWNRLD FIV+ G +E NI L+AIRT+RVLRPL+AINR+PSMRILV LLLDTLPMLGNVLLLCFFVFFIFGIIGVQ+W G+LRNR ++ S P + +YQ ++ FICS ++NGI+ C+D+P + C F + CVNWNQYYT C G NP++GAINFDNIG+AW+ IFQVI++E WV+IMYYV DAHSF+++IYF+ LII+ Sbjct: 57 VVFFCLKQTTCPRNWCIRM-------RISIMVILLNCVTLGMYQPCENIDCTSDRCQILQAFDAFIYIFFALEMVVKMVALGIFGRRCYLGDTWNRLDFFIVMAGMVEYSLDL-QNINLSAIRTVRVLRPLKAINRVPSMRILVNLLLDTLPMLGNVLLLCFFVFFIFGIIGVQLWAGLLRNRFQTKIDPSGISPPV---PYYQPEED-----DERPFICSLAQDNGIMSCTDVPTR----REGGTECCLDKEDVFVSAM---GLCVNWNQYYTRCFTGNSNPHKGAINFDNIGYAWIVIFQVITLEGWVEIMYYVMDAHSFYNFIYFIFLIIV 367 HSP 2 Score: 72.4034 bits (176), Expect = 1.513e-12 Identity = 55/156 (35.26%), Postives = 89/156 (57.05%), Query Frame = 1 Query: 3916 LFFITLNCITLAMERP--SIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKG 4377 + I LNC+TL M +P +I S L + I F EM++K+++ G+ G + YL WN +D F+V +++ ++ L + N L R +R LRPL+ I+R P ++++V LL +L +GN++L+C F IFGI+GVQL+ G Sbjct: 79 IMVILLNCVTLGMYQPCENIDCTSDRCQILQAFDAFIYIFFALEMVVKMVALGIF-GRRCYLGDTWNRLDFFIVMAGMVEY--SLDLQNIN-----LSAIRTVRVLRPLKAINRVPSMRILVNLLLDTLPMLGNVLLLCFFVFFIFGIIGVQLWAG 226
BLAST of Voltage-dependent T-type calcium channel subunit alpha vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001901.1 (pep scaffold:Pmarinus_7.0:GL477793:3961:23506:1 gene:ENSPMAG00000001722.1 transcript:ENSPMAT00000001901.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 305.834 bits (782), Expect = 1.734e-93 Identity = 163/267 (61.05%), Postives = 210/267 (78.65%), Query Frame = 1 Query: 3796 QPKGIFAKRYYHSLYVFSVDNQFRQKCQHIVDKKSFDYLVLFFITLNCITLAMERPSIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKFYYCDGPHLQAVKTKNDCLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQEN 4596 +PK +++ + SLY+F+ N+ R +C+ I+ K FD++VL FI LNCIT+A+ERP I S ERLF+T++NYIFT +F EM IKV++ L+ GD AYL+S WN +DGFLV +SL+D+ +++ RI GILRV RLLRTLRPLRVISRAPGLKLVV+TL++SL+PIGNIVLICC FFIIFGILGVQLFKGKFYYC+G + + K+DCL+ + +W KYNFDNLGQALM+LFVLSSKDGWV IMYTG+DAVG++ Q ++ Sbjct: 3 KPKFCESRKEW-SLYLFAPHNKVRMQCRKIIAHKVFDHVVLLFIFLNCITIALERPDIGADSPERLFMTISNYIFTAVFVTEMSIKVIAMALVFGDGAYLRSTWNTLDGFLVLVSLVDIIVSLASDSGARILGILRVLRLLRTLRPLRVISRAPGLKLVVETLITSLKPIGNIVLICCAFFIIFGILGVQLFKGKFYYCEGLDTKNITNKSDCLR-ANYKWLKHKYNFDNLGQALMSLFVLSSKDGWVNIMYTGLDAVGLDQQRSKD 267 HSP 2 Score: 70.4774 bits (171), Expect = 8.977e-13 Identity = 40/117 (34.19%), Postives = 64/117 (54.70%), Query Frame = 1 Query: 337 FHIFHQNKHPRDWCLKIITWPWFEQLSMTIIAVNCITLSMYQPCGDQNCETSKCQIMQAFDYIIFAFFTCEMVIKIIAMGFL-GDLGYFGDTWNRLDMFIVIVGSIEILPSTGNNIG 684 ++F + R C KII F+ + + I +NCIT+++ +P D ++ + M +YI A F EM IK+IAM + GD Y TWN LD F+V+V ++I+ S ++ G Sbjct: 15 LYLFAPHNKVRMQCRKIIAHKVFDHVVLLFIFLNCITIALERP--DIGADSPERLFMTISNYIFTAVFVTEMSIKVIAMALVFGDGAYLRSTWNTLDGFLVLVSLVDIIVSLASDSG 129 HSP 3 Score: 50.0618 bits (118), Expect = 3.375e-6 Identity = 73/249 (29.32%), Postives = 126/249 (50.60%), Query Frame = 1 Query: 4777 HLRAPLYWENYSKWRRTINSVVTSKYFDLAIAGVIGLNVITMATEFHMMPQVLKTA-----LKVFNYFFTSTFVXXXXXXXXXXXXX----RYISDKWNQLDMMIVILSIAGVVIDEVESNFMPINPTIMRVMRVLRIARVLKLLKMASGIRALLDTVIQALPQVGNXXXXXXXXXXXXXXXXVELF-GRLE-CSDINP--------CV-----GLGRHAHFENFGMAFLTLFRIATGDNWNGIMKDTL 5451 +L AP ++K R ++ K FD + I LN IT+A E P + + + + NY FT+ FV E +K++A+ L Y+ WN LD +V++S+ +++ + I I+RV+R+LR R L+++ A G++ +++T+I +L +GN+ L+ F IF LGV+LF G+ C ++ C+ L +F+N G A ++LF +++ D W IM L Sbjct: 16 YLFAP-----HNKVRMQCRKIIAHKVFDHVVLLFIFLNCITIALE---RPDIGADSPERLFMTISNYIFTAVFVTEMSIKVIAMALVFGDGAYLRSTWNTLDGFLVLVSLVDIIVSLASDSGARIL-GILRVLRLLRTLRPLRVISRAPGLKLVVETLITSLKPIGNIVLICCAFFIIFGILGVQLFKGKFYYCEGLDTKNITNKSDCLRANYKWLKHKYNFDNLGQALMSLFVLSSKDGWVNIMYTGL 255
BLAST of Voltage-dependent T-type calcium channel subunit alpha vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001900.1 (pep scaffold:Pmarinus_7.0:GL477793:3961:23576:1 gene:ENSPMAG00000001722.1 transcript:ENSPMAT00000001900.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 306.99 bits (785), Expect = 2.109e-93 Identity = 170/303 (56.11%), Postives = 227/303 (74.92%), Query Frame = 1 Query: 3796 QPKGIFAKRYYHSLYVFSVDNQFRQKCQHIVDKKSFDYLVLFFITLNCITLAMERPSIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKFYYCDGPHLQAVKTKNDCLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQ---ENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFH 4695 +PK +++ + SLY+F+ N+ R +C+ I+ K FD++VL FI LNCIT+A+ERP I S ERLF+T++NYIFT +F EM IKV++ L+ GD AYL+S WN +DGFLV +SL+D+ +++ RI GILRV RLLRTLRPLRVISRAPGLKLVV+TL++SL+PIGNIVLICC FFIIFGILGVQLFKGKFYYC+G + + K+DCL+ + +W KYNFDNLGQALM+LFVLSSKDGWV IMYTG+DAVG++ Q +N N++ ++ +FL L+ ++ M + + + H Sbjct: 3 KPKFCESRKEW-SLYLFAPHNKVRMQCRKIIAHKVFDHVVLLFIFLNCITIALERPDIGADSPERLFMTISNYIFTAVFVTEMSIKVIAMALVFGDGAYLRSTWNTLDGFLVLVSLVDIIVSLASDSGARILGILRVLRLLRTLRPLRVISRAPGLKLVVETLITSLKPIGNIVLICCAFFIIFGILGVQLFKGKFYYCEGLDTKNITNKSDCLR-ANYKWLKHKYNFDNLGQALMSLFVLSSKDGWVNIMYTGLDAVGLDQQRSKDPKNSNDFFVLKCCTFLRLLLLLLMTMMITAPLHSRH 303 HSP 2 Score: 70.8626 bits (172), Expect = 1.109e-12 Identity = 40/117 (34.19%), Postives = 64/117 (54.70%), Query Frame = 1 Query: 337 FHIFHQNKHPRDWCLKIITWPWFEQLSMTIIAVNCITLSMYQPCGDQNCETSKCQIMQAFDYIIFAFFTCEMVIKIIAMGFL-GDLGYFGDTWNRLDMFIVIVGSIEILPSTGNNIG 684 ++F + R C KII F+ + + I +NCIT+++ +P D ++ + M +YI A F EM IK+IAM + GD Y TWN LD F+V+V ++I+ S ++ G Sbjct: 15 LYLFAPHNKVRMQCRKIIAHKVFDHVVLLFIFLNCITIALERP--DIGADSPERLFMTISNYIFTAVFVTEMSIKVIAMALVFGDGAYLRSTWNTLDGFLVLVSLVDIIVSLASDSG 129 HSP 3 Score: 50.447 bits (119), Expect = 2.964e-6 Identity = 73/249 (29.32%), Postives = 126/249 (50.60%), Query Frame = 1 Query: 4777 HLRAPLYWENYSKWRRTINSVVTSKYFDLAIAGVIGLNVITMATEFHMMPQVLKTA-----LKVFNYFFTSTFVXXXXXXXXXXXXX----RYISDKWNQLDMMIVILSIAGVVIDEVESNFMPINPTIMRVMRVLRIARVLKLLKMASGIRALLDTVIQALPQVGNXXXXXXXXXXXXXXXXVELF-GRLE-CSDINP--------CV-----GLGRHAHFENFGMAFLTLFRIATGDNWNGIMKDTL 5451 +L AP ++K R ++ K FD + I LN IT+A E P + + + + NY FT+ FV E +K++A+ L Y+ WN LD +V++S+ +++ + I I+RV+R+LR R L+++ A G++ +++T+I +L +GN+ L+ F IF LGV+LF G+ C ++ C+ L +F+N G A ++LF +++ D W IM L Sbjct: 16 YLFAP-----HNKVRMQCRKIIAHKVFDHVVLLFIFLNCITIALE---RPDIGADSPERLFMTISNYIFTAVFVTEMSIKVIAMALVFGDGAYLRSTWNTLDGFLVLVSLVDIIVSLASDSGARIL-GILRVLRLLRTLRPLRVISRAPGLKLVVETLITSLKPIGNIVLICCAFFIIFGILGVQLFKGKFYYCEGLDTKNITNKSDCLRANYKWLKHKYNFDNLGQALMSLFVLSSKDGWVNIMYTGL 255
BLAST of Voltage-dependent T-type calcium channel subunit alpha vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001904.1 (pep scaffold:Pmarinus_7.0:GL477793:127370:134209:1 gene:ENSPMAG00000001732.1 transcript:ENSPMAT00000001904.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 222.631 bits (566), Expect = 1.732e-65 Identity = 159/229 (69.43%), Postives = 186/229 (81.22%), Query Frame = 1 Query: 4933 LKTALKVFNYFFTSTFVXXXXXXXXXXXXXRYISDKWNQLDMMIVILSIAGVVIDEVE-SNFMPINPTIMRVMRVLRIARVLKLLKMASGIRALLDTVIQALPQVGNXXXXXXXXXXXXXXXXVELFGRLECSDINPCVGLGRHAHFENFGMAFLTLFRIATGDNWNGIMKDTLREKCISSEDCQRNCCVS--AIIAPIYFVIFXXXXXXXXXXXXXXXXXKHLEESHK 5610 L LK NY FTS FVLEALLKL+A G+ RY D+WNQLD+ IV+LSI G++++E+E S +PINPTI+R+MRVLRI RVLKL+KMA+G++ALL V+QALPQVGNLGLLF LLF+I+AALGVELFG L C D PC GL RHA FENFGMA LTLFR++TGDNWNGIMKDTLRE SS D Q C+S +I+PIYFV FVL AQFVLVNVVVAVLMKHLE+S + Sbjct: 46 LNEGLKYCNYVFTSVFVLEALLKLLAFGIRRYFKDRWNQLDLAIVLLSIMGIILEEIEISASLPINPTIIRIMRVLRITRVLKLVKMATGMQALLAVVVQALPQVGNLGLLFLLLFFIYAALGVELFGGLTCEDY-PCEGLSRHATFENFGMALLTLFRVSTGDNWNGIMKDTLRE--CSSLDRQ---CISYLPVISPIYFVTFVLTAQFVLVNVVVAVLMKHLEDSAE 268 HSP 2 Score: 77.0258 bits (188), Expect = 3.309e-15 Identity = 65/229 (28.38%), Postives = 113/229 (49.34%), Query Frame = 1 Query: 3997 LTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFIT-ILLGHSNRI-FGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKG---KFYYCDGPHLQAVKTKNDCLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIM------YTGIDAVGVNIQPQENHNEWALIYFISFLLLVAF 4650 L NY+FT +F E ++K+L+ G+ + Y K WN +D +V +S++ + + I + S I I+R+ R+LR R L+++ A G++ ++ ++ +L +GN+ L+ F I+ LGV+LF G + Y C+G A F+N G AL+ LF +S+ D W IM + +D ++ P + IYF++F+L F Sbjct: 50 LKYCNYVFTSVFVLEALLKLLAFGI----RRYFKDRWNQLDLAIVLLSIMGIILEEIEISASLPINPTIIRIMRVLRITRVLKLVKMATGMQALLAVVVQALPQVGNLGLLFLLLFFIYAALGVELFGGLTCEDYPCEGLSRHA--------------------TFENFGMALLTLFRVSTGDNWNGIMKDTLRECSSLDRQCISYLPVISP-----IYFVTFVLTAQF 249 HSP 3 Score: 68.1662 bits (165), Expect = 2.479e-12 Identity = 49/193 (25.39%), Postives = 101/193 (52.33%), Query Frame = 1 Query: 2224 NTLSMGIEYHQQPVQLTQTLEFSNIVFSILFLIEMILKLIGEGILGYIKNGFNLFDGIIVVLGVIELCQQG---------GTSGLSILRTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKFCTIENNKRTCDRKNFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTSS 2775 ++L +++ L + L++ N VF+ +F++E +LKL+ GI Y K+ +N D IV+L ++ + + + + I+R R+ R+LKLV+ ++ L V+++ + V L +L FI++ LG+ LFG C + F++ +++T+F++ T ++WN ++ + + SS Sbjct: 31 SSLPFAVKHRGVRHSLNEGLKYCNYVFTSVFVLEALLKLLAFGIRRYFKDRWNQLDLAIVLLSIMGIILEEIEISASLPINPTIIRIMRVLRITRVLKLVKMATGMQALLAVVVQALPQVGNLGLLFLLLFFIYAALGVELFGGLTCEDYPCEGLSRHATFENFGMALLTLFRVSTGDNWNGIMKDTLRECSS 223
BLAST of Voltage-dependent T-type calcium channel subunit alpha vs. Ensembl Sea Lamprey
Match: ENSPMAT00000009098.1 (pep scaffold:Pmarinus_7.0:GL478807:14086:32911:1 gene:ENSPMAG00000008235.1 transcript:ENSPMAT00000009098.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 204.912 bits (520), Expect = 1.212e-60 Identity = 118/183 (64.48%), Postives = 147/183 (80.33%), Query Frame = 1 Query: 2173 LVNDVKFQRGILIAILINTLSMGIEYHQQPVQLTQTLEFSNIVFSILFLIEMILKLIGEGILGYIKNGFNLFDGIIVVLGVIELCQQGGTSGLSILRTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKFCTIENNKRTC-DRKNFDSLLWSIVTVFQI 2718 +VN F RGI++AILINT+SM IEYH+QP +LT LE SNIVF+ +F +EM+LK+ G+ GYI+N +N+FDG+IV++ V E+ Q G GLS+LRTFRLLR+LKLVRFMPALR+QL V++RT+DNVATF LL+LFIFIFSILGM LFGCKF + T DRKNFDSLLW+IVTVFQ+ Sbjct: 1 IVNSKYFNRGIMVAILINTVSMAIEYHEQPEELTNILEISNIVFTSMFALEMLLKIFACGLFGYIRNQYNIFDGVIVIISVWEIVGQSG-GGLSVLRTFRLLRVLKLVRFMPALRRQL-VLMRTMDNVATFCMLLMLFIFIFSILGMHLFGCKFSLKTDTGDTIPDRKNFDSLLWAIVTVFQV 181 HSP 2 Score: 72.0182 bits (175), Expect = 2.317e-14 Identity = 59/210 (28.10%), Postives = 104/210 (49.52%), Query Frame = 1 Query: 3883 IVDKKSFDYLVLFFITLNCITLAMERPSIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKFYYCDGPHLQAVKTKNDCLKYSQNEWKNQKYNFDNLGQALMALF 4512 IV+ K F+ ++ I +N +++A+E P L ++N +FT +F EM++K+ + GL Y+++ +NI DG +V IS+ + ++G S +LR FRLLR L+ +R + P L+ + L+ ++ + ++ F IF ILG+ LF KF LK + + NFD+L A++ +F Sbjct: 1 IVNSKYFNRGIMVAILINTVSMAIEYHEQPEELTN--ILEISNIVFTSMFALEMLLKIFACGLF----GYIRNQYNIFDGVIVIISVWE-----IVGQSGGGLSVLRTFRLLRVLKLVRFM---PALRRQL-VLMRTMDNVATFCMLLMLFIFIFSILGMHLFGCKF----------------SLKTDTGDTIPDRKNFDSLLWAIVTVF 179 HSP 3 Score: 57.3806 bits (137), Expect = 3.128e-9 Identity = 46/123 (37.40%), Postives = 69/123 (56.10%), Query Frame = 1 Query: 4837 VVTSKYFDLAIAGVIGLNVITMATEFHMMPQVLKTALKVFNYFFTSTFVXXXXXXXXXXXXXRYISDKWNQLDMMIVILSIAGVVIDEVESNFMPINPTIMRVMRVLRIARVLKLLKMASGIR 5205 +V SKYF+ I I +N ++MA E+H P+ L L++ N FTS F LE LLK+ A GL YI +++N D +IVI+S+ +V + V+R R+ RVLKL++ +R Sbjct: 1 IVNSKYFNRGIMVAILINTVSMAIEYHEQPEELTNILEISNIVFTSMFALEMLLKIFACGLFGYIRNQYNIFDGVIVIISVWEIVGQSGGG---------LSVLRTFRLLRVLKLVRFMPALR 114 HSP 4 Score: 51.2174 bits (121), Expect = 3.699e-7 Identity = 38/123 (30.89%), Postives = 65/123 (52.85%), Query Frame = 1 Query: 385 IITWPWFEQLSMTIIAVNCITLSMYQPCGDQNCETSKCQIMQAFDYIIFAFFTCEMVIKIIAMGFLGDLGYFGDTWNRLDMFIVIVGSIEILPSTGNNIGLTAIRTIRVLRPLRAINRIPSMR 753 I+ +F + M I +N T+SM +Q E + I++ + + + F EM++KI A G G Y + +N D IVI+ EI+ +G GL+ +RT R+LR L+ + +P++R Sbjct: 1 IVNSKYFNRGIMVAILIN--TVSMAIEYHEQPEELT--NILEISNIVFTSMFALEMLLKIFACGLFG---YIRNQYNIFDGVIVIISVWEIVGQSGG--GLSVLRTFRLLRVLKLVRFMPALR 114
BLAST of Voltage-dependent T-type calcium channel subunit alpha vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008004.1 (pep scaffold:Pmarinus_7.0:GL477228:88466:118438:1 gene:ENSPMAG00000007222.1 transcript:ENSPMAT00000008004.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 207.608 bits (527), Expect = 8.154e-54 Identity = 166/569 (29.17%), Postives = 284/569 (49.91%), Query Frame = 1 Query: 3781 SKCCPQPKGIFAKRYYHSLYVFSVDNQFRQKCQHIVDKKSFDYLVLFFITLNCITLAMERPSIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKFYYC---DGPHLQAVKTKN----DCLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFHKCQENQXXXXXXXXXXXXXXXXXXXXXHLRAP--LYWENYSKWRRTINSVVTSKYFDLAIAGVIGLNVITMATEFHMMPQVLKTALKVFNYFFTSTFVXXXXXXXXXXXXXRYISDKWNQLDMMIVILSIAGVVIDEVESNFMPINPTIMRVMRVLRIARVLKLLKMASGIRALLDTVIQALPQVGNXXXXXXXXXXXXXXXXVELFGRLECSDINPCVGLGRHAHFENFGMAFLTLFRIATGDNWNGIMKDTLREK 5460 S CC G F H++ R+ + F+ LVLF + ++ TL ++ +++ L + + F+ EM +K++ GL Y S W ++D FLV +S L+ L + LR R LR LRPLR ISR G++LVV L++S+ I N++L+C F+++FGI GVQLF GKF+ C +G L A + N + L W N N+DN+ A +AL +++ +GW++ M D+ GV+ QP N N ++ ++FI F+++ +FF+LN+F+GVV++NF+ + + ++ +R + P + ++ R +V + F+ VI LN++ +A+E + + K+ N FT F+ + Y W+ D +V +S+ +V++ + S + +P I+RV RV+R+ R+L+L++ GIR L+ T++ +LP + N+GLL L+ +++ LGV +F L S + +FE F + LFR+ T WN +M L K Sbjct: 997 SGCCGGCVGAF-----HAV---------RRMVFRLCHTTGFNGLVLFMVIMSSFTLTLDDKYNSSNAQLMQVLRYMDIFYMAFFSMEMFLKMIGLGL----HKYFTSFWTLLDCFLVLVSWLNQ-----LASAVPALKSLRSLRTLRALRPLRAISRWKGMRLVVNALVTSIPSISNVMLMCLLFWMVFGIAGVQLFGGKFFRCIDAEGNRLPATEVANRTVCESLAAEGYLWVNAIINYDNILSAYLALLQVATLEGWIEQMADASDSTGVDQQPSYNANIYSQMFFIIFVIIGSFFILNLFIGVVIDNFNSVHKREGALMALLTEDQQKFYKTMRRLYRSKPSKSIPQPQNRVLRFFYLLVHRRLFEYISTAVISLNMVMLASEHYKQSESFTNITKIINLVFTGLFM-LEAALKILGNRIHYFRQPWDIFDFFVVCISLTEIVLETMASQ-VNFSPAILRVFRVVRLVRLLRLIRSVEGIRKLIYTLVISLPALINIGLLLLLIMFMYGVLGVSIFRDLPYSG-----SITNMVNFETFANSMTLLFRLNTAGGWNDVMGSVLGTK 1535 HSP 2 Score: 76.2554 bits (186), Expect = 7.269e-14 Identity = 64/204 (31.37%), Postives = 103/204 (50.49%), Query Frame = 1 Query: 2155 QQKIKTLVNDVKFQRGILIAILINTLSMGIEYHQQPVQLTQTLEFSNIVFSILFLIEMILKLIGEGILGYIKNGFNLFDGIIVVLGVIELCQQGGTS---GLSILRTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKFCTIEN--NKRTCDRKNFDSLLWSIVTVFQILTQEDWNTVLY 2751 +Q+++TLV F+ I I I+ NT+ M I+Y+ P + L+ N V + +F+ E +LKL Y G+N+FD +V+ V+E ++ +SI+RTFR+LR+ KL + L + VM I + + L I+IF+++GM L G + N + R NF S + VF++L E W LY Sbjct: 558 RQRLRTLVTSSVFETFITILIITNTVMMAIDYYNAP--YSSALDIGNTVLTTIFIAEAVLKLTALFPRVYFHLGWNIFDFCVVITSVVEWILDSMSNTNINISIIRTFRILRVFKLAKKWKTLNLLIRVMKSAIGEMRNLTVIFALVIYIFAVIGMQLIGRDYYHNRNKFSSGQVPRWNFLDFYSSFLMVFRVLCGE-WIEPLY 758 HSP 3 Score: 75.8702 bits (185), Expect = 1.001e-13 Identity = 80/312 (25.64%), Postives = 148/312 (47.44%), Query Frame = 1 Query: 3781 SKCCPQPKGIFAKRYYHSLYVFSVDNQFRQKCQHIVDKKSFDYLVLFFITLNCITLAMERPSIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQA-YLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKFYYCDGPHLQAVKTKNDCLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFHKCQENQ 4713 SK PQP+ + +Y +V ++ F+Y+ I+LN + LA E H K+ T I ++FTG +++ K ++G++ Y + W+I D F+V ISL ++ + + N ILRVFR++R +R LR+I G++ ++ TL+ SL + NI L+ ++G+LGV +F+ D P+ ++ NF+ ++ LF L++ GW +M G + + + + YF +F++ ++NM+V +++ENF++ QE + Sbjct: 1318 SKSIPQPQNRVLRFFYL-----------------LVHRRLFEYISTAVISLNMVMLASE------HYKQSESFTNITKIINLVFTGLFMLEAALK--ILGNRIHYFRQPWDIFDFFVVCISLTEIVLETMASQVNFSPAILRVFRVVRLVRLLRLIRSVEGIRKLIYTLVISLPALINIGLLLLLIMFMYGVLGVSIFR------DLPYSGSI---------------TNMVNFETFANSMTLLFRLNTAGGWNDVM-------GSVLGTKTQNAILVIAYFTTFVIFSNIIIINMYVAIILENFNEAQEQE 1576 HSP 4 Score: 75.8702 bits (185), Expect = 1.027e-13 Identity = 41/122 (33.61%), Postives = 65/122 (53.28%), Query Frame = 1 Query: 4012 YIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKG 4377 YIFT I+TGE +IK L++G + +YL++ WN +D FI I+L + F L LR R L++I+ P LK +V + S + N++L+ II + G+Q+F+G Sbjct: 1 YIFTAIYTGEFLIKTLARGFVFHPYSYLRNAWNWLD-----------FIVIILAYMTIAFPFLPGLSALRAFRALKMIAILPALKTIVGAIFKSAGLLLNVMLLMIFALIIISLFGLQIFRG 111 HSP 5 Score: 70.4774 bits (171), Expect = 4.851e-12 Identity = 65/279 (23.30%), Postives = 128/279 (45.88%), Query Frame = 1 Query: 2173 LVNDVKFQRGILIAILIN--TLSMGIEYHQQPVQLTQTLEFSNIVFSILFLIEMILKLIGEGILGYIKNGFNLFDGIIVVLGVIELCQQG--GTSGLSILRTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKF------------CTIENNKRTCDRK------------NFDSLLWSIVTVFQILTQEDWNTVLYN-----GMTRTSSWAA-----LYFIALMTFGNYVLFNLLVAILVEGFSSERLDEQKLL 2895 L + F +L ++++ TL++ +Y+ QL Q L + +I + F +EM LK+IG G+ Y + + L D +V++ + L LRT R LR L+ + +R + ++ +I +++ + +LF +F I G+ LFG KF T N+ C+ N+D++L + + + Q+ T E W + + G+ + S+ A ++FI + G++ + NL + ++++ F+S E L+ Sbjct: 1017 LCHTTGFNGLVLFMVIMSSFTLTLDDKYNSSNAQLMQVLRYMDIFYMAFFSMEMFLKMIGLGLHKYFTSFWTLLDCFLVLVSWLNQLASAVPALKSLRSLRTLRALRPLRAISRWKGMRLVVNALVTSIPSISNVMLMCLLFWMVFGIAGVQLFGGKFFRCIDAEGNRLPATEVANRTVCESLAAEGYLWVNAIINYDNILSAYLALLQVATLEGWIEQMADASDSTGVDQQPSYNANIYSQMFFIIFVIIGSFFILNLFIGVVIDNFNSVHKREGALM 1295 HSP 6 Score: 64.3142 bits (155), Expect = 3.182e-10 Identity = 44/176 (25.00%), Postives = 89/176 (50.57%), Query Frame = 1 Query: 3862 FRQKCQHIVDKKSFDYLVLFFITLNCITLAMERPSIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKFYY 4389 FRQ+ + +V F+ + I N + +A++ + P S L + N + T IF E ++K+ + + + Y GWNI D +V S+++ +I + ++N I+R FR+LR + + + L L+++ + S++ + N+ +I IF ++G+QL +Y+ Sbjct: 557 FRQRLRTLVTSSVFETFITILIITNTVMMAIDYYNAPYSSA----LDIGNTVLTTIFIAEAVLKLTA----LFPRVYFHLGWNIFDFCVVITSVVE-WILDSMSNTNINISIIRTFRILRVFK---LAKKWKTLNLLIRVMKSAIGEMRNLTVIFALVIYIFAVIGMQLIGRDYYH 720 HSP 7 Score: 63.929 bits (154), Expect = 4.200e-10 Identity = 76/280 (27.14%), Postives = 129/280 (46.07%), Query Frame = 1 Query: 520 YIIFAFFTCEMVIKIIAMGFL-GDLGYFGDTWNRLDMFIVIVGSIEI----LPSTGNNIGLTAIRTIRVLRPLRAINRIPSMRIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQMWQGVLRNRCYLNLNESFRHPGLNLSSFYQINRTLFLNAVDKDFICSTDKNNGILKCSDIPPSIMLLSNNSLQICKQPARPFTDNLPTKHSCVNWNQYYTDCQPGEKNPYEGAINFDNIGFAWVAIFQVISMESWVDIMYYVQDAHSFWDWIYFVALIIIGSFF 1344 YI A +T E +IK +A GF+ Y + WN LD ++I+ + I LP GL+A+R R L+ I +P+++ +V + + +L NV+LL F I + G+Q+++GVLR +C N PG + S D ++ + L DI IM+ N + T + P ++C+ GE NP GA +FDN G+A + FQ+I+++ W + V A + +F+ +I++G ++ Sbjct: 1 YIFTAIYTGEFLIKTLARGFVFHPYSYLRNAWNWLDFIVIILAYMTIAFPFLP------GLSALRA---FRALKMIAILPALKTIVGAIFKSAGLLLNVMLLMIFALIIISLFGLQIFRGVLRQKCVFLPN-----PGTSSLS-------------DAEWSNYVQNKSNWLITDDI--EIMVCGNGT----------GTSHCPANYTCLP--------DIGE-NPNHGATSFDNFGWAMMTSFQIITIDYWENCYNMVLRASGQYFIGFFIVVIMLGGYY 232 HSP 8 Score: 63.929 bits (154), Expect = 4.608e-10 Identity = 44/122 (36.07%), Postives = 67/122 (54.92%), Query Frame = 1 Query: 403 FEQLSMTIIAVNCITLSMYQPCGDQNCETSKCQIMQAFDYI-IF--AFFTCEMVIKIIAMGFLGDLGYFGDTWNRLDMFIVIVGSIEILPSTGNNI-GLTAIRTIRVLRPLRAINRIPSMRI 756 F L + ++ ++ TL++ D +S Q+MQ Y+ IF AFF+ EM +K+I +G YF W LD F+V+V + L S + L ++RT+R LRPLRAI+R MR+ Sbjct: 1023 FNGLVLFMVIMSSFTLTL-----DDKYNSSNAQLMQVLRYMDIFYMAFFSMEMFLKMIGLGLHK---YFTSFWTLLDCFLVLVSWLNQLASAVPALKSLRSLRTLRALRPLRAISRWKGMRL 1136 HSP 9 Score: 58.151 bits (139), Expect = 2.288e-8 Identity = 68/277 (24.55%), Postives = 140/277 (50.54%), Query Frame = 1 Query: 2086 SKHRRPFNKNQNKTKRKNYLSICQQKIKTLVNDVKFQRGILIAILINTLSMGIEYHQQPVQLTQTLEFSNIVFSILFLIEMILKLIGEGILGYIKNGFNLFDGIIVVLGVIELCQQGGTSGLSI-------LRTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKFCTIENNKRTCDRKNFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTSSWAAL---YFIALMTFGNYVLFNLLVAILVEGFSSERLDEQ 2886 SK + + QN+ R YL LV+ F+ I +N + + E+++Q T + N+VF+ LF++E LK++G I Y + +++FD +V + + E+ + S ++ R RL+R+L+L+R + +R+ ++ ++ ++ + LL+L +F++ +LG+S+F + + + NF++ S+ +F++ T WN V+ + + + A L YF + F N ++ N+ VAI++E F+ + E+ Sbjct: 1315 SKPSKSIPQPQNRVLRFFYL---------LVHRRLFEYISTAVISLNMVMLASEHYKQSESFTNITKIINLVFTGLFMLEAALKILGNRI-HYFRQPWDIFDFFVVCISLTEIVLETMASQVNFSPAILRVFRVVRLVRLLRLIRSVEGIRKLIYTLVISLPALINIGLLLLLIMFMYGVLGVSIFR----DLPYSGSITNMVNFETFANSMTLLFRLNTAGGWNDVMGSVLGTKTQNAILVIAYFTTFVIFSNIIIINMYVAIILENFNEAQEQEE 1577 HSP 10 Score: 53.1434 bits (126), Expect = 7.971e-7 Identity = 27/85 (31.76%), Postives = 48/85 (56.47%), Query Frame = 1 Query: 1192 INFDNIGFAWVAIFQVISMESWVDIMYYVQDA----------HSFWDWIYFVALIIIGSFFMINLCLVVIASQFSETKRRETERM 1416 IN+DNI A++A+ QV ++E W++ M D+ + + ++F+ +IIGSFF++NL + V+ F+ +RE M Sbjct: 1211 INYDNILSAYLALLQVATLEGWIEQMADASDSTGVDQQPSYNANIYSQMFFIIFVIIGSFFILNLFIGVVIDNFNSVHKREGALM 1295
BLAST of Voltage-dependent T-type calcium channel subunit alpha vs. Ensembl Yeast
Match: CCH1 (Voltage-gated high-affinity calcium channel; involved in calcium influx in response to some environmental stresses as well as exposure to mating pheromones; interacts and partially co-localizes with Mid1p; however, evidence suggests CCH1 is not required for Mid1p function [Source:SGD;Acc:S000003449]) HSP 1 Score: 78.1814 bits (191), Expect = 1.443e-14 Identity = 77/331 (23.26%), Postives = 138/331 (41.69%), Query Frame = 1 Query: 3829 HSLYVFSVDNQFRQKCQHIV---------------------DKKSFDYLV-----LFFITLNCITLAMERPSIPPHSKERLFLTVTNY------IFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQ-TLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKFYYCDGPHLQAVKTKNDCLKYSQN---EWK-------NQKY-NFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVEN 4689 +S Y FS ++FR+ CQ +V +K+S+ + + +F L I L + + P + + N+ F F+ E I+K ++ G + AYL++ WN +D F V IS+ I L + N + R+F+ L LR LR ++ + + + L I LI + F + G+ +FKG+ C+ L + DC N +W Q Y + D+ A +L+ + S +GWV ++ +++ G+ + ++ + F L F+LN+FV +V N Sbjct: 1154 YSYYFFSPQHRFRRFCQRLVPPSTGKRTDGSRFFEDSTDLYNKRSYFHHIERDVFVFIFALATILLIVCSCYVTPLYRMHHKMGTWNWSSALDCAFIGAFSIEFIVKTVADGFIYSPNAYLRNPWNFID-FCVLISMWINLIAYLKNNGN----LSRIFKGLTALRALRCLTISNTARQTFNLVMFDGLNKIFEAGLISLSLLFPFTVWGLSIFKGRLGTCNDGSL----GRADCYNEYSNSVFQWDIMSPRVYQQPYLHLDSFASAFSSLYQIISLEGWVDLLENMMNSSGIGTPATVMGSAGNALFLVLFNFLSMVFILNLFVSFIVNN 1475 HSP 2 Score: 63.1586 bits (152), Expect = 5.221e-10 Identity = 58/248 (23.39%), Postives = 108/248 (43.55%), Query Frame = 1 Query: 4084 QAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKF--------------------YYCDGPHLQAVKTKND----------------CLKYSQNEWKNQKYN----FDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFHKCQE 4707 +A+ +S WN +D L +F++I S +R+F+ L LR LR+++ G+ +++ L + + N+ + F+I FGILGVQ+F+G F +C G K K + C +YS+ YN FDN+ ++ +FV+ S + + +MY +D+ + A ++FI + ++ ++LN+ + V+V +F E Sbjct: 487 RAFARSSWNRIDLVSSVSFWLGMFLSI---KSYDTKTGIRIFKPLAILRILRLVNVDTGMPSILRGLKYGIPQLVNVSSMLVYFWIFFGILGVQIFQGSFRRQCVWFNPEDPTDTYQYDMQFCGGYLDPVTKRKQNYIYEDGSEGSVSKGFLCPQYSKCVSNANPYNGRISFDNIVNSMELVFVIMSANTFTDLMYYTMDSDEMA----------ACLFFIVCIFVLTIWLLNLLIAVLVSSFEIANE 721 HSP 3 Score: 54.299 bits (129), Expect = 2.652e-7 Identity = 27/96 (28.12%), Postives = 50/96 (52.08%), Query Frame = 1 Query: 1147 YTDCQPGEKNPYEGAINFDNIGFAWVAIFQVISMESWVDIMYYVQDAHSFWDWIYFVALIIIGSFFMINLCLVVIASQFSETKRRETERMWIERRR 1434 Y+ C NPY G I+FDNI + +F ++S ++ D+MYY D+ ++F+ I + + +++NL + V+ S F ++ +I R Sbjct: 639 YSKCV-SNANPYNGRISFDNIVNSMELVFVIMSANTFTDLMYYTMDSDEMAACLFFIVCIFVLTIWLLNLLIAVLVSSFEIANEEYKKKKFIYGSR 733
BLAST of Voltage-dependent T-type calcium channel subunit alpha vs. Ensembl Nematostella
Match: EDO36844 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SHI0]) HSP 1 Score: 592.423 bits (1526), Expect = 2.212e-178 Identity = 371/720 (51.53%), Postives = 479/720 (66.53%), Query Frame = 1 Query: 3799 PKGIFAKRYYHSLYVFSVDNQFRQKCQHIVDKKSFDYLVLFFITLNCITLAMERPSIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKFYYCDGPHLQAVKTKNDCLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFHKCQENQXXXXXXXXXXXXXXXXXXXXXHLRAPLYWENYSKWRRTINSVVTSKYFDLAIAGVIGLNVITMATEFHMMPQVLKTALKVFNYFFTSTFVXXXXXXXXXXXXXRYISDKWNQLDMMIVILSIAGVVIDEVESNFMPINPTIMRVMRVLRIARVLKLLKMASGIRALLDTVIQALPQVGNXXXXXXXXXXXXXXXXVELFGRLECSDIN-PCVGLGRHAHFENFGMAFLTLFRIATGDNWNGIMKDTLREKCISSEDCQRN----CCVSAIIAPIYFVIFXXXXXXXXXXXXXXXXXKHLEESHKMMCDDYELEREVQRDLDEEAKELAREKQLKDEENNENTLIDIEIDKNNNFLDKKENNSINQNQIKKLSCGDCHSINAQLRNVSCQNVHLVNIYSKN-------LSRSHPHL 5922 P +KR SLYVF+ DN+FR + + K FD VL FI LNC+ +A+E PS+ P S ER + + Y+F IFT EM++KV++ GL IG AYL+SGWN+MDGFLV IS +D+ +T N I G+LRVFR LRTLRPLRVISRAPGLK+VV+TL+SSL+PIGNIVLI TFFIIFGILGVQLFKGKF+YC + V TK +CL+ + W N++YNFDNL +AL+ LFV S+KDGWV IMY GIDAVG++ QP NH + +IYF+ FLLL F VLNM VGVVVENF KC+ E E+K K + + +R+ E+Y + R+ I++V T YFDL IA VI LNV+ MA E + P L LK NY FT+ F+LEA+LK+ ALG+ RYI D+WNQLDM+IVILSI G+ ++E+ +PINPTI+RVMRVLRIARVLKLLK A GIR LLDTV QALPQVGNLG+LF L+F+IF+ALG+ELFG+++C C G+ HA+F +FG+A LTLFRI+TGDNWNGI+KDT IS + C+ N C + +APIYF +FVL QFVL+NVVVAVLMKHLEE+ ++ + ++ + + KD NN +L D+ +F D+ +N S +++ + C ++N Q N L I ++ LSRS P L Sbjct: 899 PTSCCSKRADWSLYVFAPDNRFRMLNKELYQNKWFDRTVLLFILLNCVVMALEGPSVLPGSLERRVIDICMYVFLGIFTIEMMVKVIALGLWIGPDAYLRSGWNVMDGFLVVISWVDVIVTATTNGQNSILGVLRVFRALRTLRPLRVISRAPGLKIVVETLISSLKPIGNIVLIAATFFIIFGILGVQLFKGKFHYCTDATV-PVTTKTECLE-NGGSWVNREYNFDNLAKALLTLFVFSTKDGWVNIMYDGIDAVGIDKQPIRNHARYNVIYFVGFLLLAGFVVLNMLVGVVVENFQKCRTLIEMEKKIDEEKKNKKEEKMRREIAEDEALSEHYPRPRKFIHAVCTHGYFDLGIAAVIALNVLCMALEHYQQPDGLTAFLKCANYVFTAVFILEAILKIFALGIKRYIKDRWNQLDMLIVILSIVGIALEEMTME-LPINPTIIRVMRVLRIARVLKLLKTAEGIRKLLDTVAQALPQVGNLGMLFLLMFFIFSALGIELFGKIDCEKPGITCQGMDEHANFRSFGIAMLTLFRISTGDNWNGILKDT-----ISPDVCRVNPEIDCSMLEHVAPIYFAVFVLATQFVLLNVVVAVLMKHLEEA-----------KDTKTPVNTPPLSSSSRESSKD--NNGASLKVPSSDRKVSFDDEADNYSKPESRSSR--CLPMVAVNGQGYNSFDNEFGLQGITRQDAIKPPAMLSRSAPSL 1595 HSP 2 Score: 258.455 bits (659), Expect = 4.076e-69 Identity = 139/228 (60.96%), Postives = 175/228 (76.75%), Query Frame = 1 Query: 2191 FQRGILIAILINTLSMGIEYHQQPVQLTQTLEFSNIVFSILFLIEMILKLIGEGILGYIKNGFNLFDGIIVVLGVIELCQQGGTSGLSILRTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKFCTIENNKRTCD--RKNFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTSSWAALYFIALMTFGNYVLFNLLVAILVEGFSS 2868 F I+ AI +NTL+MGIEY+ QP ++T LE N +F+ +F IEMI+KLIG G GYIK+ FN+FDG IV++ V+EL SG+S+LR+FRLLR+ KLVRF+PALR+QL VMI T+DNV TF ALL++F+F SILGM+LFG K+ N++ + R NFD L W+IVTVFQ+LTQEDWN V+Y+GM TS WA LYFI LMT GNY+LFNLLVAILVEGF+S Sbjct: 413 FMYVIMGAIFVNTLTMGIEYYGQPQKMTDVLEIFNYIFTAIFGIEMIMKLIGLGFYGYIKDAFNIFDGTIVIISVVELFGDD-DSGISVLRSFRLLRVFKLVRFLPALRRQLLVMIHTMDNVMTFLALLVIFMFTASILGMNLFGGKY-RFPNDEGVMETSRANFDDLFWAIVTVFQVLTQEDWNIVMYDGMRATSKWAGLYFILLMTIGNYILFNLLVAILVEGFAS 638 HSP 3 Score: 211.846 bits (538), Expect = 7.409e-55 Identity = 133/250 (53.20%), Postives = 169/250 (67.60%), Query Frame = 1 Query: 685 LTAIRTIRVLRPLRAINRIPSMRIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQMWQGVLRNRCYLNLNESFRHPGLNLSSFYQINRTLFLNAVDKDFICSTDKNNGILKCSDIPPSIMLLSNNSLQICKQPARPFTDNLPTKHSCVNWNQYYTDCQPGEKNPYEGAINFDNIGFAWVAIFQVISMESWVDIMYYVQDAHSFWDWIYFVALIIIGSFFMINLCLVVIASQFSETKRRETERMWIERRR 1434 +TA+R IRVLRPLRAINR+PS+RILV LLLDTLPMLGNVL +C +F IFGI+GVQMWQGVLR+RC L + LN+S+FYQ + D +CS +N+G C+ + + S + C +++ + C NWNQYYT C NP A++FDNI AWVAIFQVI++E W DIMYY+QDAH FW++IYFV LI+IGS+FM NLCLVVI +QF ETK+RE + M RR+ Sbjct: 1 MTAVRAIRVLRPLRAINRVPSIRILVTLLLDTLPMLGNVLAMCSLIFSIFGIVGVQMWQGVLRSRCVAQLPGNLSANQLNISAFYQPGGS-------SDLVCSLPENSGDKHCTS---AFIPASTAHGRECGLTYEQYSNRSNYTNVCANWNQYYTLCADMGINPLYDAVSFDNILIAWVAIFQVITLEGWTDIMYYIQDAHGFWNFIYFVVLIVIGSYFMTNLCLVVITTQFQETKQRENDLMRQSRRK 240 HSP 4 Score: 119.783 bits (299), Expect = 8.184e-27 Identity = 80/278 (28.78%), Postives = 138/278 (49.64%), Query Frame = 1 Query: 3859 QFRQKCQHIVDKKSFDYLVLFFITLNCITLAMERPSIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKFYYCDGPHLQAVKTKNDCLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENF 4692 +FR C VD K F Y+++ I +N +T+ +E P K L + NYIFT IF EMI+K++ G Y+K +NI DG +V IS+++LF G + +LR FRLLR + +R + P L+ + ++ ++ + + + F ILG+ LF GK+ + ND + + + NFD+L A++ +F + +++ W +MY G+ A ++WA +YFI + + + + N+ V ++VE F Sbjct: 399 KFRDGCASSVDSKWFMYVIMGAIFVNTLTMGIEYYGQP--QKMTDVLEIFNYIFTAIFGIEMIMKLIGLGFY----GYIKDAFNIFDGTIVIISVVELF-----GDDDSGISVLRSFRLLRVFKLVRFL---PALRRQLLVMIHTMDNVMTFLALLVIFMFTASILGMNLFGGKYRF-----------PND-----EGVMETSRANFDDLFWAIVTVFQVLTQEDWNIVMYDGMRAT----------SKWAGLYFILLMTIGNYILFNLLVAILVEGF 636 HSP 5 Score: 98.5969 bits (244), Expect = 2.758e-20 Identity = 80/277 (28.88%), Postives = 139/277 (50.18%), Query Frame = 1 Query: 2167 KTLVNDVKFQRGILIAILINTLSMGIEYHQQPVQLTQTLEFSNI-----VFSILFLIEMILKLIGEGIL----GYIKNGFNLFDGIIVVLGVIELCQQGGTSG----LSILRTFRLLRILKLVRFM---PALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKF--CT------------IENNKRTCDRK-NFDSLLWSIVTVFQILTQEDWNTVLYNGMTRT----------SSWAALYFIALMTFGNYVLFNLLVAILVEGFSSER 2874 K L + F R +L+ IL+N + M +E P L +LE I VF +F IEM++K+I G+ Y+++G+N+ DG +VV+ +++ T+G L +LR FR LR L+ +R + P L+ + +I ++ + + F IF ILG+ LF KF CT +EN +R+ NFD+L +++T+F T++ W ++Y+G+ + + +YF+ + +V+ N+LV ++VE F R Sbjct: 925 KELYQNKWFDRTVLLFILLNCVVMALE---GPSVLPGSLERRVIDICMYVFLGIFTIEMMVKVIALGLWIGPDAYLRSGWNVMDGFLVVISWVDVIVTATTNGQNSILGVLRVFRALRTLRPLRVISRAPGLKIVVETLISSLKPIGNIVLIAATFFIIFGILGVQLFKGKFHYCTDATVPVTTKTECLENGGSWVNREYNFDNLAKALLTLFVFSTKDGWVNIMYDGIDAVGIDKQPIRNHARYNVIYFVGFLLLAGFVVLNMLVGVVVENFQKCR 1198 HSP 6 Score: 97.0561 bits (240), Expect = 8.036e-20 Identity = 69/197 (35.03%), Postives = 109/197 (55.33%), Query Frame = 1 Query: 2191 FQRGILIAILINTLSMGIEYHQQPVQLTQTLEFSNIVFSILFLIEMILKLIGEGILGYIKNGFNLFDGIIVVLGVIELCQQGGTSGLSI-------LRTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKFCTIENNKRTC----DRKNFDSLLWSIVTVFQILTQEDWNTVL 2748 F GI I +N L M +E++QQP LT L+ +N VF+ +F++E ILK+ GI YIK+ +N D +IV+L ++ + + T L I +R R+ R+LKL++ +R+ L + + + V L +L FIFS LG+ LFG C E TC + NF S +++T+F+I T ++WN +L Sbjct: 1249 FDLGIAAVIALNVLCMALEHYQQPDGLTAFLKCANYVFTAVFILEAILKIFALGIKRYIKDRWNQLDMLIVILSIVGIALEEMTMELPINPTIIRVMRVLRIARVLKLLKTAEGIRKLLDTVAQALPQVGNLGMLFLLMFFIFSALGIELFGKIDC--EKPGITCQGMDEHANFRSFGIAMLTLFRISTGDNWNGIL 1443 HSP 7 Score: 85.8853 bits (211), Expect = 1.923e-16 Identity = 67/215 (31.16%), Postives = 111/215 (51.63%), Query Frame = 1 Query: 4810 SKWRRTINSVVTSKYFDLAIAGVIGLNVITMATEFHMMPQVLKTALKVFNYFFTSTFVXXXXXXXXXXXXXRYISDKWNQLDMMIVILSIAGVVIDEVESNFMPINPTIMRVMRVLRIARVLKLLKMASGIRALLDTVIQALPQVGNXXXXXXXXXXXXXXXXVELFGRLECSDINPCVGLGRHAHFENFGMAFLTLFRIATGDNWNGIMKDTLR 5454 +K+R S V SK+F I G I +N +TM E++ PQ + L++FNY FT+ F +E ++KL+ LG YI D +N D IVI+S+ + D+ + V+R R+ RV KL++ +R L +I + V L + + + LG+ LFG + V A+F++ A +T+F++ T ++WN +M D +R Sbjct: 398 AKFRDGCASSVDSKWFMYVIMGAIFVNTLTMGIEYYGQPQKMTDVLEIFNYIFTAIFGIEMIMKLIGLGFYGYIKDAFNIFDGTIVIISVVELFGDDDSG---------ISVLRSFRLLRVFKLVRFLPALRRQLLVMIHTMDNVMTFLALLVIFMFTASILGMNLFGGKYRFPNDEGVMETSRANFDDLFWAIVTVFQVLTQEDWNIVMYDGMR 603 HSP 8 Score: 70.4774 bits (171), Expect = 9.036e-12 Identity = 36/126 (28.57%), Postives = 70/126 (55.56%), Query Frame = 1 Query: 400 WFEQLSMTIIAVNCITLSMYQPCGDQNCETSKCQIMQAFDYIIFAFFTCEMVIKIIAMG-FLGDLGYFGDTWNRLDMFIVIVGSIEILPSTGNN-----IG-LTAIRTIRVLRPLRAINRIPSMRI 756 WF++ + I +NC+ +++ P + + +++ Y+ FT EM++K+IA+G ++G Y WN +D F+V++ ++++ + N +G L R +R LRPLR I+R P ++I Sbjct: 932 WFDRTVLLFILLNCVVMALEGPSVLPG--SLERRVIDICMYVFLGIFTIEMMVKVIALGLWIGPDAYLRSGWNVMDGFLVVISWVDVIVTATTNGQNSILGVLRVFRALRTLRPLRVISRAPGLKI 1055 HSP 9 Score: 65.855 bits (159), Expect = 2.068e-10 Identity = 38/129 (29.46%), Postives = 67/129 (51.94%), Query Frame = 1 Query: 367 RDWCLKIITWPWFEQLSMTIIAVNCITLSMYQPCGDQNCETSKCQIMQAFDYIIFAFFTCEMVIKIIAMGFLGDLGYFGDTWNRLDMFIVIVGSIEILPSTGNNIGLTAIRTIRVLRPLRAINRIPSMR 753 RD C + WF + M I VN +T+ + Q +++ F+YI A F EM++K+I +GF GY D +N D IVI+ +E+ ++ G++ +R+ R+LR + + +P++R Sbjct: 401 RDGCASSVDSKWFMYVIMGAIFVNTLTMGIEYYGQPQK----MTDVLEIFNYIFTAIFGIEMIMKLIGLGF---YGYIKDAFNIFDGTIVIISVVELF--GDDDSGISVLRSFRLLRVFKLVRFLPALR 520 HSP 10 Score: 62.003 bits (149), Expect = 3.185e-9 Identity = 26/60 (43.33%), Postives = 42/60 (70.00%), Query Frame = 1 Query: 4198 LRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKG 4377 + R +R LRPLR I+R P ++++V LL +L +GN++ +C F IFGI+GVQ+++G Sbjct: 1 MTAVRAIRVLRPLRAINRVPSIRILVTLLLDTLPMLGNVLAMCSLIFSIFGIVGVQMWQG 60 HSP 11 Score: 54.6842 bits (130), Expect = 5.579e-7 Identity = 23/66 (34.85%), Postives = 40/66 (60.61%), Query Frame = 1 Query: 1195 NFDNIGFAWVAIFQVISMESWVDIMYYVQDAHSFWDWIYFVALIIIGSFFMINLCLVVIASQFSET 1392 NFD++ +A V +FQV++ E W +MY A S W +YF+ L+ IG++ + NL + ++ F+ Sbjct: 574 NFDDLFWAIVTVFQVLTQEDWNIVMYDGMRATSKWAGLYFILLMTIGNYILFNLLVAILVEGFASA 639 HSP 12 Score: 53.5286 bits (127), Expect = 1.251e-6 Identity = 26/86 (30.23%), Postives = 46/86 (53.49%), Query Frame = 1 Query: 2665 DRKNFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTSSWAALYFIALMTFGNYVLFNLLVAILVEGFSSERLDEQKLLHNYRQSLKK 2922 D +FD++L + V +FQ++T E W ++Y W +YF+ L+ G+Y + NL + ++ F + E L+ RQS +K Sbjct: 158 DAVSFDNILIAWVAIFQVITLEGWTDIMYYIQDAHGFWNFIYFVVLIVIGSYFMTNLCLVVITTQFQETKQRENDLM---RQSRRK 240 HSP 13 Score: 50.447 bits (119), Expect = 9.342e-6 Identity = 43/135 (31.85%), Postives = 62/135 (45.93%), Query Frame = 1 Query: 361 HPRDWCLKIITWPWFEQLSMTIIAVN--CITLSMYQ-PCGDQNCETSKCQIMQAFDYIIFAFFTCEMVIKIIAMGFLGDLGYFGDTWNRLDMFIVIVGSIEI--------LPSTGNNIGLTAIRTIRVLRPLRAI 732 PR + + T +F+ +IA+N C+ L YQ P G ++ +Y+ A F E ++KI A+G Y D WN+LDM IVI+ + I LP I T IR +RVLR R + Sbjct: 1235 RPRKFIHAVCTHGYFDLGIAAVIALNVLCMALEHYQQPDG-------LTAFLKCANYVFTAVFILEAILKIFALGIKR---YIKDRWNQLDMLIVILSIVGIALEEMTMELP-----INPTIIRVMRVLRIARVL 1354
BLAST of Voltage-dependent T-type calcium channel subunit alpha vs. Ensembl Nematostella
Match: EDO35497 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SLD1]) HSP 1 Score: 495.352 bits (1274), Expect = 2.987e-157 Identity = 280/528 (53.03%), Postives = 382/528 (72.35%), Query Frame = 1 Query: 3859 QFRQKCQHIVDKKSFDYLVLFFITLNCITLAMERPSIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKFYYCDGPHLQAVKTKNDCLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFHKCQENQXXXXXXXXXXXXXXXXXXXXXHLRAPLYWENYSKWRRTINSVVTSKYFDLAIAGVIGLNVITMATEFHMMPQVLKTALKVFNYFFTSTFVXXXXXXXXXXXXXRYISDKWNQLDMMIVILSIAGVVIDEVESNFMPINPTIMRVMRVLRIARVLKLLKMASGIRALLDTVIQALPQVGNXXXXXXXXXXXXXXXXVELFGRLECSDINPCVGLGRHAHFENFGMAFLTLFRIATGDNWNGIMK 5442 +FRQ+ + + ++FDY++L FI +C LA+E P I +R + ++ +FTIIFT EM+IK+++ GL++G YL+ GW+++DGFLV +S +D+ +T S + G LRVFR LRTLRPLRVI RAPGLKLVVQTLL SL+PIGN VLI FF++FGILGVQLFKGKFYYC+G V +K +C ++ +W N++YNFD+L QAL++LFV+S+KDGWV+IM+ GIDAV V++QP N+ EW L+YFI FLLL F VLNM VGVVVENF +C+E A+ R+ +K R ++ LY+E+Y R I+ + T + +D+ IA +I +NVI M+ E + MPQV ++ NYFFTS FV+E ++K++ALG RY D+WN +D+ IV+LS+ G+V++ + NPT++R +RVLRI RVLKL+K+A G+R+LLDT+ +ALPQV NLGLLFFLLF+I++ LG++LFG LECS PC G RHAHF +FG A LTLFRIATGDNWNGI+K Sbjct: 7 RFRQRMRAVCSHRAFDYVILVFIIFSCAVLAIEAPDIAEQGLKRQIIDISMLVFTIIFTIEMLIKLVAMGLVLGPGTYLRDGWDVLDGFLVMVSWIDIIVTYTSHVSPEVLGTLRVFRALRTLRPLRVIRRAPGLKLVVQTLLYSLKPIGNTVLIAAIFFVMFGILGVQLFKGKFYYCEGD--SHVISKQECANSTRGQWVNRRYNFDDLLQALISLFVVSTKDGWVEIMHHGIDAVDVDVQPIVNYAEWRLVYFIPFLLLGGFLVLNMIVGVVVENFQRCRERM----DEEEQARPHRKGKKARNQMQDSLYYESYGPLRLKIHFICTHRNWDITIAAIICINVICMSLEHYKMPQVF---VETTNYFFTSVFVIEVVVKVIALGFVRYPKDRWNLIDLAIVLLSVTGIVLELLVKVDHLFNPTVIRTLRVLRITRVLKLVKLAKGVRSLLDTLFEALPQVPNLGLLFFLLFFIYSCLGIQLFGSLECSHDYPCQGFNRHAHFRDFGTAMLTLFRIATGDNWNGILK 525 HSP 2 Score: 93.5893 bits (231), Expect = 2.897e-19 Identity = 76/298 (25.50%), Postives = 155/298 (52.01%), Query Frame = 1 Query: 2155 QQKIKTLVNDVKFQRGILIAILINTLSMGIE---YHQQPVQLTQTLEFSNIVFSILFLIEMILKLIGEG-ILG---YIKNGFNLFDGIIVVLGVIELCQQGGT-------SGLSILRTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKFCTIENN-----KRTCD----------RKNFDSLLWSIVTVFQILTQEDWNTVLYNGMTRT----------SSWAALYFIALMTFGNYVLFNLLVAILVEGFS--SERLDEQKLLHNYRQSLKKR 2925 +Q+++ + + F IL+ I+ + + IE +Q ++ Q ++ S +VF+I+F IEM++KL+ G +LG Y+++G+++ DG +V++ I++ + L + R R LR L+++R P L+ + ++ ++ + + +F +F ILG+ LF KF E + K+ C R NFD LL +++++F + T++ W ++++G+ + W +YFI + G +++ N++V ++VE F ER+DE++ +R+ K R Sbjct: 9 RQRMRAVCSHRAFDYVILVFIIFSCAVLAIEAPDIAEQGLK-RQIIDISMLVFTIIFTIEMLIKLVAMGLVLGPGTYLRDGWDVLDGFLVMVSWIDIIVTYTSHVSPEVLGTLRVFRALRTLRPLRVIRRAPGLKLVVQTLLYSLKPIGNTVLIAAIFFVMFGILGVQLFKGKFYYCEGDSHVISKQECANSTRGQWVNRRYNFDDLLQALISLFVVSTKDGWVEIMHHGIDAVDVDVQPIVNYAEWRLVYFIPFLLLGGFLVLNMIVGVVVENFQRCRERMDEEEQARPHRKGKKAR 305 HSP 3 Score: 65.0846 bits (157), Expect = 1.900e-10 Identity = 41/125 (32.80%), Postives = 66/125 (52.80%), Query Frame = 1 Query: 403 FEQLSMTIIAVNCITLSMYQPCGDQNCETSKCQIMQAFDYIIFAFFTCEMVIKIIAMGF-LGDLGYFGDTWNRLDMFIVIVGSIEILPSTGNNIG------LTAIRTIRVLRPLRAINRIPSMRI 756 F+ + + I +C L++ P D + K QI+ + FT EM+IK++AMG LG Y D W+ LD F+V+V I+I+ + +++ L R +R LRPLR I R P +++ Sbjct: 21 FDYVILVFIIFSCAVLAIEAP--DIAEQGLKRQIIDISMLVFTIIFTIEMLIKLVAMGLVLGPGTYLRDGWDVLDGFLVMVSWIDIIVTYTSHVSPEVLGTLRVFRALRTLRPLRVIRRAPGLKL 143 HSP 4 Score: 57.3806 bits (137), Expect = 5.969e-8 Identity = 65/240 (27.08%), Postives = 121/240 (50.42%), Query Frame = 1 Query: 2083 YSKHRRPFNKNQNKTKRKNYLSICQQKIKTLVNDVKFQRGILIAILINTLSMGIEYHQQPVQLTQTLEFSNIVFSILFLIEMILKLIGEGILGYIKNGFNLFDGIIVVLGV--------IELCQQGGTSGLSILRTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKFCTIENNKRTCDR-KNFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTSS 2775 + K ++ N+ Q+ ++Y + + KI + + I I IN + M +E+++ P +T +N F+ +F+IE+++K+I G + Y K+ +NL D IV+L V +++ + + LR R+ R+LKLV+ +R L + + V L L FI+S LG+ LFG C+ + + +R +F +++T+F+I T ++WN +L G T T + Sbjct: 298 HRKGKKARNQMQDSLYYESYGPL-RLKIHFICTHRNWDITIAAIICINVICMSLEHYKMPQVFVET---TNYFFTSVFVIEVVVKVIALGFVRYPKDRWNLIDLAIVLLSVTGIVLELLVKVDHLFNPTVIRTLRVLRITRVLKLVKLAKGVRSLLDTLFEALPQVPNLGLLFFLLFFIYSCLGIQLFGSLECSHDYPCQGFNRHAHFRDFGTAMLTLFRIATGDNWNGILKVGPTNTVT 533
BLAST of Voltage-dependent T-type calcium channel subunit alpha vs. Ensembl Nematostella
Match: EDO35498 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SLD2]) HSP 1 Score: 283.493 bits (724), Expect = 7.802e-81 Identity = 181/340 (53.24%), Postives = 230/340 (67.65%), Query Frame = 1 Query: 400 WFEQLSMTIIAVNCITLSMYQPCGDQNCETSKCQIMQAFDYIIFAFFTCEMVIKIIAMGFLGDLGYFGDTWNRLDMFIVIVGSIEILPSTGNNIGLTAIRTIRVLRPLRAINRIPSMRIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQMWQGVLRNRCYLNLNESFRHPGLNLSSFYQINRTLFLNAVDKDFICSTDKNNGILKC-SDIPPSIMLLSNNSLQICKQPARPFTDNLPTKHSCVNWNQYYTDCQPGEKNPYEGAINFDNIGFAWVAIFQVISMESWVDIMYYVQDAHSFWDWIYFVALIIIGSFFMINLCLVVIASQFSETKRRETERM 1416 WFE++SM II VNCITL+MY P D+ CE +C +++ F++ IF FF EMV+K++AMG G GY DTWN+LD I+++G IE S + LT IR RVLRPLRAIN++PS+RILV LLLDTLPMLGNVLLL F VFF+FGIIGVQ+WQG LRNRC+ + N++ N S FY+ + + DF+CS N G+ C SDIP S + + Q C P T N +C +WN Y DC+ NP+ G I+FDNI AW+ IFQVI++E W D+MY VQD HSFW+WIYF+ LI+IG+FF++NLCLVVI QF ETK RE E M Sbjct: 4 WFERISMVIILVNCITLAMYDPL-DKRCEKVRCNVLEKFEFFIFGFFLLEMVVKMVAMGVFGSHGYLQDTWNKLDFVIIVMGVIE--KSLQGSDYLTIIRAFRVLRPLRAINKVPSIRILVTLLLDTLPMLGNVLLLSFLVFFVFGIIGVQLWQGKLRNRCFASTNDTALLLSFNQSVFYKPS------FIQPDFVCSGPTNTGMTSCLSDIPHSYL----HGRQ-CTLPPENLTSN---SSNCADWNSLYRDCREDGPNPFWGTISFDNIAIAWMVIFQVITLEGWSDVMYLVQDTHSFWNWIYFIILIVIGAFFLVNLCLVVITMQFQETKAREIELM 326 HSP 2 Score: 212.231 bits (539), Expect = 7.005e-57 Identity = 133/249 (53.41%), Postives = 166/249 (66.67%), Query Frame = 1 Query: 2191 FQRGILIAILINTLSMGIEYHQQPVQLTQTLEFSNIVFSILFLIEMILKLIGEGILGYIKNGFNLFDGIIVVLGVIELCQQGGTSGLSILRTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKFCTI-ENNKRTCDRKNFDSLLWSIVTVFQ----------------------ILTQEDWNTVLYNGMTRTSSWAALYFIALMTFGNYVLFNLLVAILVEGFSS 2868 F R I+IAIL+N + MG+E+H QP LT TLE +NIVF +F++EMI+ +I GI+GY+ N+FDG +VVL V EL + G + LS+ R+ RLLRI KLVR +R QL V+IRT+ +V TFF LL LF+F F+ILGM+LFG +F N R NFDS LW++VTVFQ ILTQE+WN V++ GM TS WAALYFIALMT G YVLFNLLVAILVEGF+S Sbjct: 485 FSRLIMIAILLNMICMGLEHHNQPQALTVTLEKTNIVFVTIFVLEMIINVISFGIMGYLSQLQNIFDGFVVVLSVTELLLENGYARLSVFRSIRLLRIFKLVR---PVRYQLLVVIRTMTSVVTFFGLLFLFMFAFAILGMNLFGGEFYFPNAENISVPARTNFDSFLWAMVTVFQVRRGSCHGDDVPYEKKIIAMVTILTQENWNQVMFKGMRATSYWAALYFIALMTVGYYVLFNLLVAILVEGFTS 730 HSP 3 Score: 90.1225 bits (222), Expect = 4.944e-18 Identity = 75/289 (25.95%), Postives = 146/289 (50.52%), Query Frame = 1 Query: 3847 SVDNQFRQKCQHIVDKKSFDYLVLFFITLNCITLAMERPSIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSN-RIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKFYYCDGPHLQA-VKTKNDCLKYSQN---EWKNQKYNFDNLG--QALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENF 4692 V ++FR C+ + + + F L++ I LN I + +E + P + L TN +F IF EMII V+S G++ YL NI DGF+V +S+ +L + G++ +F +R+ R+ + +RP+R L +V++T+ S + + F F ILG+ LF G+FY+ + ++ +T D ++ + + + D++ + ++A+ + +++ W Q+M+ G+ A + WA +YFI+ + + + + N+ V ++VE F Sbjct: 467 GVVHRFRAFCRRMAESRHFSRLIMIAILLNMICMGLEHHNQP--QALTVTLEKTNIVFVTIFVLEMIINVISFGIM----GYLSQLQNIFDGFVVVLSVTELLLEN--GYARLSVFRSIRLLRIFKLVRPVRY-----QLLVVIRTMTS----VVTFFGLLFLFMFAFAILGMNLFGGEFYFPNAENISVPARTNFDSFLWAMVTVFQVRRGSCHGDDVPYEKKIIAMVTILTQENWNQVMFKGMRAT----------SYWAALYFIALMTVGYYVLFNLLVAILVEGF 728 HSP 4 Score: 80.8777 bits (198), Expect = 4.263e-15 Identity = 54/165 (32.73%), Postives = 87/165 (52.73%), Query Frame = 1 Query: 3901 FDYLVLFFITLNCITLAMERPSIPPHSKERL-FLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIF---GILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKF 4383 F+ + + I +NCITLAM P K R L + F EM++K+++ G+ G YL+ WN +D F+ I++G + L + R R LRPLR I++ P ++++V LL +L +GN++L+ F +FGI+GVQL++GK Sbjct: 5 FERISMVIILVNCITLAMYDPLDKRCEKVRCNVLEKFEFFIFGFFLLEMVVKMVAMGVF-GSHGYLQDTWNKLD-----------FVIIVMGVIEKSLQGSDYLTIIRAFRVLRPLRAINKVPSIRILVTLLLDTLPMLGNVLLLSFLVFFVFGIIGVQLWQGKL 157 HSP 5 Score: 50.447 bits (119), Expect = 7.762e-6 Identity = 26/77 (33.77%), Postives = 52/77 (67.53%), Query Frame = 1 Query: 2326 MILKLIGEGILG---YIKNGFNLFDGIIVVLGVIELCQQGGTSGLSILRTFRLLRILKLVRFMPALRQQLFVMIRTI 2547 M++K++ G+ G Y+++ +N D +I+V+GVIE Q G+ L+I+R FR+LR L+ + +P++R + +++ T+ Sbjct: 53 MVVKMVAMGVFGSHGYLQDTWNKLDFVIIVMGVIEKSLQ-GSDYLTIIRAFRVLRPLRAINKVPSIRILVTLLLDTL 128 HSP 6 Score: 50.0618 bits (118), Expect = 9.927e-6 Identity = 60/236 (25.42%), Postives = 105/236 (44.49%), Query Frame = 1 Query: 4813 KWRRTINSVVTSKYFDLAIAGVIGLNVITMATEFHMMPQVLKTALKVFNYFFTSTFVXXXXXXXXXXXXXRYISDKWNQLDMMIVILSIAGVVIDEVESNFMPINPTIMRVMRVLRIARVLKLLKMASGIRALLDTVIQALPQVGNXXXXXXXXXXXXXXXXVELFGRLECSDINPCVGLGRHAHFENFGMAFLTLFRIATG----------------------DNWNGIMKDTLR 5454 ++R + S++F I I LN+I M E H PQ L L+ N F + FVLE ++ +++ G+ Y+S N D +V+LS+ ++++ + + V R R+L++ K+ +R L VI+ + V L FL + FA LG+ LFG + + +F++F A +T+F++ G +NWN +M +R Sbjct: 471 RFRAFCRRMAESRHFSRLIMIAILLNMICMGLEHHNQPQALTVTLEKTNIVFVTIFVLEMIINVISFGIMGYLSQLQNIFDGFVVVLSVTELLLENGYAR-----------LSVFRSIRLLRIFKLVRPVRYQLLVVIRTMTSVVTFFGLLFLFMFAFAILGMNLFGGEFYFPNAENISVPARTNFDSFLWAMVTVFQVRRGSCHGDDVPYEKKIIAMVTILTQENWNQVMFKGMR 695
BLAST of Voltage-dependent T-type calcium channel subunit alpha vs. Ensembl Nematostella
Match: EDO46991 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RNU9]) HSP 1 Score: 231.491 bits (589), Expect = 8.327e-61 Identity = 187/563 (33.21%), Postives = 309/563 (54.88%), Query Frame = 1 Query: 3832 SLYVFSVDNQFRQKCQHIVDKKSFDYLVLFFITLNCITLAMERPSIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKFYYC-DGPHLQAVKTKNDCLKY----------SQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFHKCQENQXXXXXXXXXXXXXXXXXXXXXHLR--APLYWENYSKWRRTINSVVTSKYFDLAIAGVIGLNVITMATEFHMMPQVLKTALKVFNYFFTSTFVXXXXXXXXXXXXXRYISDKWNQLDMMIVILSIAGVVIDEVESNFMPINPTIMRVMRVLRIARVLKLLKMASGIRALLDTVI---QALPQVGNXXXXXXXXXXXXXXXXVELFGRLECSDINPCVGLGRHAHFENFGMAFLTLFRIATGDNWNGIM---KDTLREKC 5463 SL++FS N FR C I F +L I ++ LA E P + +SK L +Y FT +FT E+ IK+++ G+++ ++ +S +N++D +V +S+ ++I L S+ ++R+ R+LR LRPLR I+RA GLK VVQ + +++ IGNI+L+ F +F ++GVQLFKG F+ C D + + + +++ EW+ Q +NF+++ QA++ LF + + +GW I+ + +D+ V+ P N+ W IY++ +++++AFF++N+FVG V+ F E + K+ + + ++ K + R P + WR VVTS+ F+ I I N I + +++ P++ L FN FTS F+LE +LKL A Y D+WN D ++V+ S+ + ++EV S M R+ R R++KLL SGI+ LL T I QALP VG LL + F+I+A +G+++FGR+ I+P + R+ +F+ F + + LFR ATG+NW IM DT KC Sbjct: 812 SLFIFSNTNCFRVVCHRIATNSYFVNFILLLIIVSSCMLAAEDP-LNSNSKRNQVLNYFDYFFTAVFTIEITIKIIAYGVILHKGSFCRSAFNLLDFLVVAVSI----VSIALRDSSSQISVVRILRVLRVLRPLRAINRAKGLKHVVQCVFVAVKTIGNIMLVTVLFNFLFAVIGVQLFKGTFFSCTDAEKITKRECQGQYIEFKGPGLTNPVVKDREWQPQTFNFNDVPQAMLTLFTVMTFEGWPGILESSMDSTDVDEGPFLNNRPWVAIYYVIYIIIIAFFMINIFVGFVIVTFQNEGEEEFKDCELDKNQRKCVEFALKARPTRRYIPTNRLQFHVWR-----VVTSQPFEYLIFAFITGNTILLMMQYYNEPKLYTRVLDGFNIGFTSVFLLECILKLFAFKPKNYFLDRWNLFDFVVVVGSVVDITMNEVSSEQM----FAFGFFRLFRALRLVKLLNQGSGIKTLLWTFIKSFQALPYVG---LLIIMTFFIYAVVGMQMFGRIA---IDPETQINRNNNFQTFPQSLMVLFRSATGENWQLIMLACTDTPNAKC 1354 HSP 2 Score: 150.214 bits (378), Expect = 4.328e-36 Identity = 101/344 (29.36%), Postives = 168/344 (48.84%), Query Frame = 1 Query: 3781 SKCCPQPK----GIFAKRYYHSLYVFSVDNQFRQKCQHI-------VDKKSFDYLVLFFITLNCITLAMERPSIPPHSKERLF---LTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKFYYC-----------DGPHLQAVKTKN----------DCLKYSQNEWKNQKY---NFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFHK 4698 K PQPK A R +L+ ++ N R + V + FD ++L I NC LA +P P L L V ++F IFT E ++K+++ G ++ AYL++GWNI+D +V + L + + + S + + R R LRPLR++S P L++V+ +++ +L P+ +I L+ II+ I+GV+LF GK + D PH + +++ CLK +W+ Y NFDN+G A + +F + +GW +MY+ DA+G N W +YF++ ++ +FFVLN+ +GV+ F K Sbjct: 25 GKPPPQPKRQKKPTNAVRPKRALFCLTLGNPIRSTAISLFTVFFLDVFRTPFDVMILITIFANCAALAAFQPL--PEQDSSLINEELEVAEFVFLGIFTMESVLKIIAYGFVMHPGAYLRNGWNILDFVIVVVGLATIIVKLYTPDSFDV----KALRAFRVLRPLRLVSGVPSLQVVLNSIIKALIPLFHIALLVVFVVIIYAIIGVELFMGKLHSTCYDNVTGQPTFDEPHPCSTESEGYSCSNAGPGQVCLK----KWEGPNYGITNFDNIGLACLTVFQCITLEGWTDVMYSINDAIG---------NSWPWLYFVTLIIWGSFFVLNLVLGVLSGEFAK 349 HSP 3 Score: 137.887 bits (346), Expect = 2.677e-32 Identity = 121/412 (29.37%), Postives = 188/412 (45.63%), Query Frame = 1 Query: 178 PQDNRSRRETLIGNKSDFNLTDKSKADHCQQETDGTPINPNESLIYHGFYATVFHIFHQNKHPRDWCLKIITWPWFEQLSMTIIAVNCITLSMYQPCGDQNCETSKCQIMQAFDYIIFAFFTCEMVIKIIAMGFLGDLG-YFGDTWNRLDMFIVIVGSIEILPS--TGNNIGLTAIRTIRVLRPLRAINRIPSMRIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQMWQGVLRNRCYLNLNESFRHPGLNLSSFYQINRTLFLNAVDKDFICSTDKNNGILKCSDIPPSIMLLSNNSLQICKQPARPFTDNLPTKHSCVNWNQYYTDCQPGEKNPYEGAINFDNIGFAWVAIFQVISMESWVDIMYYVQDA-HSFWDWIYFVALIIIGSFFMINLCLVVIASQFSETKRR 1401 PQ R ++ T N +A C T G PI ++ F+ VF + P F+ + + I NC L+ +QP +Q+ ++ A +++ FT E V+KIIA GF+ G Y + WN LD IV+VG I+ T ++ + A+R RVLRPLR ++ +PS+++++ ++ L L ++ LL FV I+ IIGV+++ G L + CY N+ D+ CST+ CS+ P Q+C + W + P G NFDNIG A + +FQ I++E W D+MY + DA + W W+YFV LII GSFF++NL L V++ +F++ K R Sbjct: 29 PQPKRQKKPT--------NAVRPKRALFCL--TLGNPIRSTAISLFTVFFLDVF------RTP------------FDVMILITIFANCAALAAFQPLPEQDSSLINEELEVA-EFVFLGIFTMESVLKIIAYGFVMHPGAYLRNGWNILDFVIVVVGLATIIVKLYTPDSFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKALIPLFHIALLVVFVVIIYAIIGVELFMGKLHSTCYDNVTGQ--------------------PTFDEPHPCSTESEG--YSCSNAGPG---------QVCLK----------------KW-----------EGPNYGITNFDNIGLACLTVFQCITLEGWTDVMYSINDAIGNSWPWLYFVTLIIWGSFFVLNLVLGVLSGEFAKEKAR 353 HSP 4 Score: 137.502 bits (345), Expect = 3.814e-32 Identity = 91/252 (36.11%), Postives = 145/252 (57.54%), Query Frame = 1 Query: 2152 CQQKIKTLVNDVKFQRGILIAILINTLSMGIEYHQQPVQLTQTLEFSNIVFSILFLIEMILKLIGEGILGYIKNGFNLFDGIIVVLGVIELCQQGGTS----GLSILRTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKFCTIENNKRTCDRKNFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTSSWAA----------LYFIALMTFGNYVLFNLLVAILVEGFS 2865 C++ +KT F +++ + +N+L++ +E++ QP LTQ L+ +N +F LF +EM++K+ G GY + FN FD ++V+ ++EL G+S+LR RLLRI K+ R+ +L + ++ ++ ++ LL LF+ IFS+LGM +FG KF + + R NFDS ++VTVFQILT EDWN V+Y G+ SW LYFI L+ GNY+L N+ +AI V+ + Sbjct: 451 CRKAVKTQW----FYWTVIVFVFLNSLTLALEHYNQPEFLTQFLDKANKLFLALFTLEMVVKMYCLGFHGYFASLFNRFDCLVVISSLLELGLTEAMDQRPIGISMLRCVRLLRIFKVTRYWSSLSNLVASLLNSMRSIMGLLLLLSLFMVIFSLLGMQIFGGKFNLGDED---VPRSNFDSFWRALVTVFQILTGEDWNAVMYTGI---QSWGGITESLSAIPILYFIFLVVVGNYILLNVFLAIAVDNLA 692 HSP 5 Score: 112.079 bits (279), Expect = 1.794e-24 Identity = 87/296 (29.39%), Postives = 147/296 (49.66%), Query Frame = 1 Query: 3817 KRYYHSLYVFSVDNQFRQKCQHIVDKKSFDYLVLFFITLNCITLAMERPSIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKFYYCDGPHLQAVKTKNDCLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFHKCQ 4704 KR++H L R+ C+ V + F + V+ F+ LN +TLA+E + P + FL N +F +FT EM++K+ +G Y S +N D +V SLL+L +T + +LR RLLR + R S L +V +LL+S+R I ++L+ F +IF +LG+Q+F GKF D D + NFD+ +AL+ +F + + + W +MYTGI + G E+ + ++YFI +++ + +LN+F+ + V+N + Sbjct: 441 KRFHHRL---------RRSCRKAVKTQWFYWTVIVFVFLNSLTLALEHYNQPEFLTQ--FLDKANKLFLALFTLEMVVKMYC----LGFHGYFASLFNRFDCLVVISSLLELGLTEAMDQRPIGISMLRCVRLLRIFKVTRYWS---SLSNLVASLLNSMRSIMGLLLLLSLFMVIFSLLGMQIFGGKFNLGD----------EDV----------PRSNFDSFWRALVTVFQILTGEDWNAVMYTGIQSWG---GITESLSAIPILYFIFLVVVGNYILLNVFLAIAVDNLADAE 695 HSP 6 Score: 91.6633 bits (226), Expect = 2.772e-18 Identity = 74/287 (25.78%), Postives = 135/287 (47.04%), Query Frame = 1 Query: 3856 NQFRQKCQHIVDKKSFDYLVLFFITLNCITLAMERPSIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKFYYCDGPHLQAVKTKNDCLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGV----NIQPQENHN----EWALIYFISFLLLVAFFVLNMFVGVVVENF 4692 N+ + +V + F+YL+ FIT N I L M+ +++ +L+ V + F I FT +++ + K + Y WN+ D +V S++D+ + + FG FRL R LR ++++++ G+K ++ T + S + + + L+ F I+ ++G+Q+F G+ P Q N+ NF Q+LM LF ++ + W IM D N PQ+ ++A YF SF + +F ++N+FV V+++NF Sbjct: 1141 NRLQFHVWRVVTSQPFEYLIFAFITGNTILLMMQY-----YNEPKLYTRVLDG-FNIGFTSVFLLECILKLFAFKPKNYFLDRWNLFDFVVVVGSVVDITMNEVSSEQMFAFGF---FRLFRALRLVKLLNQGSGIKTLLWTFIKSFQALPYVGLLIIMTFFIYAVVGMQMF-GRI--AIDPETQI----------------NRNNNFQTFPQSLMVLFRSATGENWQLIMLACTDTPNAKCDPNAYPQDTDGLCGTDFAYAYFCSFYAICSFLIINLFVAVIMDNF 1399 HSP 7 Score: 90.8929 bits (224), Expect = 5.346e-18 Identity = 77/282 (27.30%), Postives = 136/282 (48.23%), Query Frame = 1 Query: 2191 FQRGILIAILINTLSMGIEYHQQPVQ----LTQTLEFSNIVFSILFLIEMILKLIGEGIL----GYIKNGFNLFDGIIVVLGVIELCQQGGTS---GLSILRTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKF-------------------CTIENNKRTCDRK------------------NFDSLLWSIVTVFQILTQEDWNTVLYN-GMTRTSSWAALYFIALMTFGNYVLFNLLVAILVEGFSSERLDEQK 2889 F ILI I N ++ + P Q + + LE + VF +F +E +LK+I G + Y++NG+N+ D +IVV+G+ + + T + LR FR+LR L+LV +P+L+ L +I+ + + L++ + I++I+G+ LF K C+ E+ +C NFD++ + +TVFQ +T E W V+Y+ +SW LYF+ L+ +G++ + NL++ +L F+ E+ QK Sbjct: 76 FDVMILITIFANCAALA-AFQPLPEQDSSLINEELEVAEFVFLGIFTMESVLKIIAYGFVMHPGAYLRNGWNILDFVIVVVGLATIIVKLYTPDSFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKALIPLFHIALLVVFVVIIYAIIGVELFMGKLHSTCYDNVTGQPTFDEPHPCSTESEGYSCSNAGPGQVCLKKWEGPNYGITNFDNIGLACLTVFQCITLEGWTDVMYSINDAIGNSWPWLYFVTLIIWGSFFVLNLVLGVLSGEFAKEKARAQK 356 HSP 8 Score: 70.8626 bits (172), Expect = 6.309e-12 Identity = 75/251 (29.88%), Postives = 111/251 (44.22%), Query Frame = 1 Query: 55 KKSENK-VERKKYSLDSFPSSVF---YEANEFLEIENEIECLDILPQDNRSRRETLIGNKSDFNLTDKSKA----DH-------CQQETDGTPINPNESLIYHGFYATVFHIFHQNKHPRDWCLKIITWPWFEQLSMTIIAVNCITLSMYQPCGDQNCETSKCQIMQAFDYIIFAFFTCEMVIKIIAMGFLGDLGYF-GDTWNRLDMFIVIVGSIEI-LPSTGNNIGLTAI-RTIRVLRPLRAINRIPSMR 753 + S NK +E K+ S S S ++ NE L + +I +R R+ + +S +L + SKA DH + D P+ P SL IF R C +I T +F + +I V+ L+ P N + + Q++ FDY A FT E+ IKIIA G + G F +N LD +V V + I L + + I + I R +RVLRPLRAINR ++ Sbjct: 722 ESSSNKDLENKRASTSSGKSHRLIKIWKTNELLHLAGKIRV-------SRLRKHPITDAESP-SLAEDSKATLNRDHESVRSATSTEVMDHEPMPPESSLF----------IFSNTNCFRVVCHRIATNSYFVNFILLLIIVSSCMLAAEDPL---NSNSKRNQVLNYFDYFFTAVFTIEITIKIIAYGVILHKGSFCRSAFNLLDFLVVAVSIVSIALRDSSSQISVVRILRVLRVLRPLRAINRAKGLK 951 HSP 9 Score: 66.2402 bits (160), Expect = 1.570e-10 Identity = 71/285 (24.91%), Postives = 134/285 (47.02%), Query Frame = 1 Query: 2107 NKNQNK----------TKRKNYLSICQQKIKTLVNDVKFQRGILIAILINTLSMGIEYHQQPVQLTQTLEFSNIVFSILFLIEMILKLIGEGILGYIKNGFNLFDGIIVVLGVIELCQQGGTS----GLSILRTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKFCTIENNKRTCDRKNFDSLLWSIVTVFQILTQEDWNTVLY-------------------NGMTRTSSWAALYFIALMTFGNYVLFNLLVAILVEGF 2862 +KNQ K T+R + Q + +V F+ I I NT+ + ++Y+ +P T+ L+ NI F+ +FL+E ILKL Y + +NLFD ++VV V+++ +S R FR LR++KL+ ++ L+ I++ + L+I+ FI++++GM +FG I+ + NF + S++ +F+ T E+W ++ +G+ T +A YF + ++++ NL VA++++ F Sbjct: 1118 DKNQRKCVEFALKARPTRRYIPTNRLQFHVWRVVTSQPFEYLIFAFITGNTILLMMQYYNEPKLYTRVLDGFNIGFTSVFLLECILKLFAFKPKNYFLDRWNLFDFVVVVGSVVDITMNEVSSEQMFAFGFFRLFRALRLVKLLNQGSGIKTLLWTFIKSFQALPYVGLLIIMTFFIYAVVGMQMFGR--IAIDPETQINRNNNFQTFPQSLMVLFRSATGENWQLIMLACTDTPNAKCDPNAYPQDTDGLCGT-DFAYAYFCSFYAICSFLIINLFVAVIMDNF 1399 HSP 10 Score: 63.1586 bits (152), Expect = 1.575e-9 Identity = 66/246 (26.83%), Postives = 126/246 (51.22%), Query Frame = 1 Query: 4807 YSKWRRTINSVVTSKYFDLAIAGVIGLNVITMATEFHMMPQVLKTALKVFNYFFTSTFVXXXXXXXXXXXXXRYISDKWNQLDMMIVILSIAGVVIDEVESNFMPINPTIMRVMRVLRIARVLKLLKMASGIRALLDTVIQALPQVGNXXXXXXXXXXXXXXXXVELFG---RLECSDINPCVGLGRHAHFENFGMAFLTLFRIATGDNWNGIMKDTLREKCISSEDCQRNCCVSAIIAPIYFVIF 5535 + + RR+ V +++F + + LN +T+A E + P+ L L N F + F LE ++K+ LG Y + +N+ D ++VI S+ + + E M P + ++R +R+ R+ K+ + S + L+ +++ ++ + L LL L IF+ LG+++FG L D+ ++F++F A +T+F+I TG++WN +M ++ +E +SAI PI + IF Sbjct: 444 HHRLRRSCRKAVKTQWFYWTVIVFVFLNSLTLALEHYNQPEFLTQFLDKANKLFLALFTLEMVVKMYCLGFHGYFASLFNRFDCLVVISSLLELGLTEA----MDQRPIGISMLRCVRLLRIFKVTRYWSSLSNLVASLLNSMRSIMGLLLLLSLFMVIFSLLGMQIFGGKFNLGDEDVP-------RSNFDSFWRALVTVFQILTGEDWNAVMYTGIQSWGGITES------LSAI--PILYFIF 670 HSP 11 Score: 62.003 bits (149), Expect = 3.562e-9 Identity = 53/203 (26.11%), Postives = 104/203 (51.23%), Query Frame = 1 Query: 2275 QTLEFSNIVFSILFLIEMILKLIGEGIL----GYIKNGFNLFDGIIVVLGVIELCQQGGTSGLSILRTFRLLRILKLVRFMPALR------QQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKF--CTIEN--NKRTC------------------DRK------NFDSLLWSIVTVFQILTQEDWNTVLYNGMTRT 2769 Q L + + F+ +F IE+ +K+I G++ + ++ FNL D ++V + ++ + + +S +S++R R+LR+L+ +R + + Q +FV ++TI N+ + +LF F+F+++G+ LF F CT KR C DR+ NF+ + +++T+F ++T E W +L + M T Sbjct: 864 QVLNYFDYFFTAVFTIEITIKIIAYGVILHKGSFCRSAFNLLDFLVVAVSIVSIALRDSSSQISVVRILRVLRVLRPLRAINRAKGLKHVVQCVFVAVKTIGNI---MLVTVLFNFLFAVIGVQLFKGTFFSCTDAEKITKRECQGQYIEFKGPGLTNPVVKDREWQPQTFNFNDVPQAMLTLFTVMTFEGWPGILESSMDST 1063 HSP 12 Score: 52.7582 bits (125), Expect = 2.059e-6 Identity = 34/120 (28.33%), Postives = 58/120 (48.33%), Query Frame = 1 Query: 367 RDWCLKIITWPWFEQLSMTIIAVNCITLSMYQPCGDQNCETSKCQIMQAFDYIIFAFFTCEMVIKIIAMGFLGDLGYFGDTWNRLDMFIVIVGSIEILPSTGNN---IGLTAIRTIRVLR 717 R C K + WF + + +N +TL++ N Q + + + A FT EMV+K+ +GF G YF +NR D +VI +E+ + + IG++ +R +R+LR Sbjct: 448 RRSCRKAVKTQWFYWTVIVFVFLNSLTLALEH----YNQPEFLTQFLDKANKLFLALFTLEMVVKMYCLGFHG---YFASLFNRFDCLVVISSLLELGLTEAMDQRPIGISMLRCVRLLR 560
BLAST of Voltage-dependent T-type calcium channel subunit alpha vs. Ensembl Nematostella
Match: EDO35661 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SKR1]) HSP 1 Score: 230.72 bits (587), Expect = 8.918e-61 Identity = 200/640 (31.25%), Postives = 341/640 (53.28%), Query Frame = 1 Query: 3865 RQKCQHIVDKKSFDYLVLFFITLNCITLAMERPSIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKFYYC---DGPHLQA--VKTKNDCLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFHKCQENQXXXXXXXXXXXXX----------XXXXXXXXHLRAPLYWENYSKWRRTINSVVTSKYFDLAIAGVIGLNVITMATEFHMMPQVLKTALKVFNYFFTSTFVXXXXXXXXXXXXXRYISDKWNQLDMMIVILSIAGVVIDEVESNFMPINPTIMRVMRVLRIARVLKLLKMASGIRALLDTVIQALPQVGNXXXXXXXXXXXXXXXXVELFGRLECSDINPCVGLGRHAHFENFGMAFLTLFRIATGDNWNGIMKDTLREKCISSEDCQRNC-------CVSAIIAPIY---FVIFXXXXXXXXXXXXXXXXXKHLEESHKMMC--DDYELEREVQRDLDEEAKELAREKQLKD 5703 R K + +V+ K F+ ++LF I + I+LA E + + L + N +F +IFT EM++K + +G + Y + WNI+D +V +S++ TI N +R R LR RPLR ISR G+K+V+ +LL ++ IGN++L+C F++IF I+GVQ+F GKF C G A V K CL + W+N NFD + Q +AL +++ +GW++IM +DA ++ QP E +N A ++F+ F++L FF LN+F+GV+++NF++ ++ E +K +K +R P +K++ + +V S+ F++ I I +N++ M + + V ++ N FTS F+LEA+L+++AL Y + WN D +IVI SI G++++ ++++ + INP+++RV+RV R+ R+L+ + A GIR LL +++ + P + N+G L FL+ +I+A +G+ +FG ++ ++ L +FE FG +F+ LFR+ T WN D L IS DC N C + +APIY FV+ + + + V+ + E K+ +D EL ++ D A + L D Sbjct: 817 RYKVRRLVEHKVFEGIILFLIAASSISLAFEDVYLDSKPTLKQVLQILNILFAVIFTVEMLLKWIG----LGFKTYFTNPWNILDFVIVIVSIMVSLATIF---GNDQIAFIRSLRTLRAFRPLRAISRFEGMKVVITSLLHAIPGIGNVLLVCLMFWLIFSIMGVQIFGGKFGKCVDEGGEKCPASVVPNKTVCLS-NGYRWENSNINFDTVDQGFLALLQVATFEGWMEIMEDAVDATKIDEQPIEENNVSAYLFFVVFIILGTFFTLNLFIGVIIDNFNQLKQQMEAVGSMDVFLTSTQRNWMNALKSAATKKPKKRIRRP-----QNKFQGELYDMVQSRKFEVFIMLFITINMVVMMVQHYDHLAVWSK--QILNLIFTSVFILEAILRIIALRKG-YFLNPWNVFDFVIVISSIIGIIVENLQTSLV-INPSLLRVVRVFRVGRLLRFFEAARGIRRLLFSLVISTPALFNIGALLFLIIFIYAIIGMSIFGHVKKTE-----ALNDVVNFETFGSSFVLLFRLMTSAGWN----DILDPLMISEPDCDPNYRGLPSGNCGNKYMAPIYLGSFVVIIFLILINMYIAVILENYNQVMEQEKIGITNEDIELFYQMWELFDPNATQYIPYADLSD 1430 HSP 2 Score: 123.25 bits (308), Expect = 7.777e-28 Identity = 86/282 (30.50%), Postives = 150/282 (53.19%), Query Frame = 1 Query: 2020 VASRSSSINSCAYQIPRLTDSYSKHRRPFNKNQNKTKRKNYLSICQQKIKTLVNDVKFQRG------ILIAILINTLSMGIEYHQQPVQLTQTLEFSNIVFSILFLIEMILKLIGEGILGYIKNGFNLFDGIIVVLGVIE-----LCQQGGTSGLSILRTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKFCTIENNKRTCDRKNFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTSSWAALYFIALMTFGNYVLFN 2832 + S+ S++N+ + I S H+ N + K ++K + ++ + +KF G I++ IL+NTL M IE+ + L + SN VF+ +FL+EMILKLI G LGYI+ +N+FDGI+V++ +++ G +G+S+LRTFRLLR+LKL + + L + +++ + +L + ++IF+++GM L G + T + + R NF S + +F++L E W L++ M T A L F+ GN+++ N Sbjct: 449 IGSQKSNLNNASQII-------SSHKSSLNLSVKKEEKKRSSIMARRWKRFRRRLLKFTNGKVMEIFIIVCILLNTLVMSIEHPRLEDPLLTVVNISNEVFTFIFLLEMILKLIALGFLGYIRVAWNIFDGIVVIISIVDFIVNKFVPDAGGTGISVLRTFRLLRVLKLAKSWSTMNSLLATIGKSLGALGNLTVILAIIVYIFAVMGMQLLGNSY-TPDKFGGSIPRWNFKDFPHSFMMIFRVLCGE-WIEPLWDCMLATGPVAMLLFVPAFILGNFIILN 721 HSP 3 Score: 108.227 bits (269), Expect = 2.633e-23 Identity = 114/379 (30.08%), Postives = 174/379 (45.91%), Query Frame = 1 Query: 340 HIFHQNKHPRDWCLKIITWPWFEQLS------MTIIAVNCITLSMYQPCGDQNCETSKCQIMQAFDYIIFAFFTCEMVIKIIAMGF-LGDLGYFGDTWNRLDMFIVIVGSIEILPSTGNNIGLTAIRTIRVLRPLRAINRIPSMRIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQMWQGVLRNRCYLNLNESFRHPGLNLSSFYQINRTLFLNAVDKDFICSTDKNNGILKCSDIPPSIMLLSNNSLQICKQPARPFTDNLPTKHSCVNWNQYYTDCQPGEKNPYEGAINFDNIGFAWVAIFQVISMESWVDIMYYVQDAHSFWDWIYFVALIIIGSFFMINLCLVVIASQFS---ETKRRETERMWIERRRFNSS 1446 ++F R + LK+IT + QL + I VNC+ L+M P +Y+ A +T EM KIIA GF L Y D WN LD +VI+G++ I P N L+ I T RV R LR I+ + ++ +V LL ++ ML +V++L F IF +IG+Q++ G LRN+C L + E NLS Y RT N+ SI L +N +C + PT ++C+ NP G +FD+ G+A + FQ+I+++ W ++ V W +YF +I G FF++NL L V+A+ + + + ETE E++R SS Sbjct: 25 YLFGPENPIRQFSLKLITNQYPLQLHNRHMFVLLTILVNCVFLAMTNPPEQP-------------EYVFAAIYTIEMFCKIIAKGFALHRYAYLRDKWNWLDFIVVILGNVTISPDVAN---LSGIPTFRVFRALRTISAVKGLKAMVNTLLVSMKMLWDVMVLTLFFICIFALIGMQLFIGELRNKCALPVPE-------NLSVPY---RTYASNS-----------------------SIWYLEDNEPILCGNTTG--SRTCPTNYTCL---------PHAGGNPNFGYTSFDHFGWALLTGFQLITLDFWENVYNNVIYTMGPWYVVYFAVVIFFGPFFLVNLVLAVVAASYENEVKASKMETEEERKEQKRVASS 343 HSP 4 Score: 95.9005 bits (237), Expect = 1.508e-19 Identity = 89/336 (26.49%), Postives = 141/336 (41.96%), Query Frame = 1 Query: 3832 SLYVFSVDNQFRQKC------QHIVDKKSFDYLVLFFITLNCITLAMERPSIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSN------RIFGI--LRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKF-------------------------YYCDG--PHL-------QAVKTKNDCLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFH 4695 SLY+F +N RQ Q+ + + VL I +NC+ LAM P P Y+F I+T EM K+++KG + AYL+ WN +D FI ++LG+ + GI RVFR LRT IS GLK +V TLL S++ + +++++ F IF ++G+QLF G+ +Y + P L + T CL ++ +FD+ G AL+ F L + D W + I +G W ++YF + FF++N+ + VV ++ Sbjct: 23 SLYLFGPENPIRQFSLKLITNQYPLQLHNRHMFVLLTILVNCVFLAMTNPPEQPE-----------YVFAAIYTIEMFCKIIAKGFALHRYAYLRDKWNWLD-----------FIVVILGNVTISPDVANLSGIPTFRVFRALRT------ISAVKGLKAMVNTLLVSMKMLWDVMVLTLFFICIFALIGMQLFIGELRNKCALPVPENLSVPYRTYASNSSIWYLEDNEPILCGNTTGSRTCPTNYTCLPHAGGNPNFGYTSFDHFGWALLTGFQLITLDFWENVYNNVIYTMG----------PWYVVYFAVVIFFGPFFLVNLVLAVVAASYE 320 HSP 5 Score: 81.2629 bits (199), Expect = 4.122e-15 Identity = 68/276 (24.64%), Postives = 130/276 (47.10%), Query Frame = 1 Query: 2149 ICQQKIKTLVNDVKFQRGILIAILINTLSMGIE--YHQQPVQLTQTLEFSNIVFSILFLIEMILKLIGEGILGYIKNGFNLFDGIIVVLGV-IELCQQGGTSGLSILRTFRLLRILKLVRFMP---ALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKF--CTIEN----------NKRTC---------DRKNFDSLLWSIVTVFQILTQEDWNTVLYNGMTRT----------SSWAALYFIALMTFGNYVLFNLLVAILVEGFS 2865 + + K++ LV F+ IL I +++S+ E Y L Q L+ NI+F+++F +EM+LK IG G Y N +N+ D +IV++ + + L G ++ +R+ R LR + +R + ++ + ++ I + + ++F IFSI+G+ +FG KF C E NK C NFD++ + + Q+ T E W ++ + + T + A L+F+ + G + NL + ++++ F+ Sbjct: 815 VMRYKVRRLVEHKVFEGIILFLIAASSISLAFEDVYLDSKPTLKQVLQILNILFAVIFTVEMLLKWIGLGFKTYFTNPWNILDFVIVIVSIMVSLATIFGNDQIAFIRSLRTLRAFRPLRAISRFEGMKVVITSLLHAIPGIGNVLLVCLMFWLIFSIMGVQIFGGKFGKCVDEGGEKCPASVVPNKTVCLSNGYRWENSNINFDTVDQGFLALLQVATFEGWMEIMEDAVDATKIDEQPIEENNVSAYLFFVVFIILGTFFTLNLFIGVIIDNFN 1090 HSP 6 Score: 77.411 bits (189), Expect = 6.706e-14 Identity = 69/262 (26.34%), Postives = 121/262 (46.18%), Query Frame = 1 Query: 3889 DKKSFDYLVLFFITLNCITLAMERPSIPPHSKERLFLTVTNY---IFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRI-FGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKFYYCDGPHLQAVKTKNDCLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLN 4662 + K + ++ I LN + +++E P + E LTV N +FT IF EMI+K+++ G L Y++ WNI DG +V IS++D + + + +LR FRLLR L+ + S L + T+ SL +GN+ +I IF ++G+QL G Y D K+ + ++NF + + M +F + + W++ ++ + A G A++ F+ +L F +LN Sbjct: 501 NGKVMEIFIIVCILLNTLVMSIEHPRL-----EDPLLTVVNISNEVFTFIFLLEMILKLIALGFL----GYIRVAWNIFDGIVVIISIVDFIVNKFVPDAGGTGISVLRTFRLLRVLKLAKSWSTMNSL---LATIGKSLGALGNLTVILAIIVYIFAVMGMQLL-GNSYTPD--------------KFGGSI---PRWNFKDFPHSFMMIFRVLCGE-WIEPLWDCMLATG----------PVAMLLFVPAFILGNFIILN 721 HSP 7 Score: 70.8626 bits (172), Expect = 6.132e-12 Identity = 69/305 (22.62%), Postives = 123/305 (40.33%), Query Frame = 1 Query: 2203 ILIAILINTLSMGIEYHQQPVQLTQTLEFSNIVFSILFLIEMILKLIGEGI----LGYIKNGFNLFDGIIVVLGVIELCQQ-GGTSGLSILRTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLF------GCKFCTIEN-----------------------------NKRTC----------------DRKNFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTSSWAALYFIALMTFGNYVLFNLLVAILVEGFSSERLDEQKLLHNYRQSLKKRRANNKQLR 2949 +L+ IL+N + + +T E VF+ ++ IEM K+I +G Y+++ +N D I+V+LG + + SG+ R FR LR + V+ + A+ L V ++ + +V I + GM LF C EN RTC +FD W+++T FQ++T + W V N + W +YF ++ FG + L NL++A++ + +E + K+ + +KR A++ +R Sbjct: 56 VLLTILVNCVFLA---------MTNPPEQPEYVFAAIYTIEMFCKIIAKGFALHRYAYLRDKWNWLDFIVVILGNVTISPDVANLSGIPTFRVFRALRTISAVKGLKAMVNTLLVSMKMLWDVMVLTLFFICIFALI---GMQLFIGELRNKCALPVPENLSVPYRTYASNSSIWYLEDNEPILCGNTTGSRTCPTNYTCLPHAGGNPNFGYTSFDHFGWALLTGFQLITLDFWENVYNNVIYTMGPWYVVYFAVVIFFGPFFLVNLVLAVVAASYENE-VKASKMETEEERKEQKRVASSYSVR 347 HSP 8 Score: 63.5438 bits (153), Expect = 1.137e-9 Identity = 66/193 (34.20%), Postives = 107/193 (55.44%), Query Frame = 1 Query: 4846 SKYFDLAIAGVIGLNVITMATEFHMMPQVLKTALKVFNYFFTSTFVXXXXXXXXXXXXXRYISDKWNQLDMMIVILSIAGVVIDEVESNFMP-INPTIMRVMRVLRIARVLKLLKMASGIRALLDTVIQALPQVGNXXXXXXXXXXXXXXXXVELFGRLECSDINPCVGLGRHAHFENFGMAFLTLFRIATGD 5421 K ++ I I LN + M+ E + L T + + N FT F+LE +LKL+ALG YI WN D ++VI+SI +D + + F+P T + V+R R+ RVLKL K S + +LL T+ ++L +GNL ++ ++ YIFA +G++L G D G +F++F +F+ +FR+ G+ Sbjct: 502 GKVMEIFIIVCILLNTLVMSIEHPRLEDPLLTVVNISNEVFTFIFLLEMILKLIALGFLGYIRVAWNIFDGIVVIISI----VDFIVNKFVPDAGGTGISVLRTFRLLRVLKLAKSWSTMNSLLATIGKSLGALGNLTVILAIIVYIFAVMGMQLLGNSYTPD--KFGGSIPRWNFKDFPHSFMMIFRVLCGE 688 HSP 9 Score: 61.2326 bits (147), Expect = 5.308e-9 Identity = 40/121 (33.06%), Postives = 65/121 (53.72%), Query Frame = 1 Query: 403 FEQLSMTIIAVNCITLSMYQPCGDQNCETSKCQIMQAFDYIIFAFFTCEMVIKIIAMGFLGDLGYFGDTWNRLDMFIVIVGSIEILPSTGNNIGLT---AIRTIRVLRPLRAINRIPSMRI 756 FE + + +IA + I+L+ D + + Q++Q + + FT EM++K I +GF YF + WN LD IVIV + L + N + ++RT+R RPLRAI+R M++ Sbjct: 829 FEGIILFLIAASSISLAFEDVYLDS--KPTLKQVLQILNILFAVIFTVEMLLKWIGLGFKT---YFTNPWNILDFVIVIVSIMVSLATIFGNDQIAFIRSLRTLRAFRPLRAISRFEGMKV 944 HSP 10 Score: 57.3806 bits (137), Expect = 7.283e-8 Identity = 68/304 (22.37%), Postives = 142/304 (46.71%), Query Frame = 1 Query: 3856 NQFRQKCQHIVDKKSFDYLVLFFITLNCITLAMER-PSIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLL-----DLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKFYYCDGPHLQAVKTKNDCLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWAL------------IYFISFLLLVAFFVLNMFVGVVVENFHKCQENQ 4713 N+F+ + +V + F+ ++ FIT+N + + ++ + SK+ + N IFT +F E I+++++ + Y + WN+ D +V S++ +L ++++ S RV R+ R R LR A G++ ++ +L+ S + NI + I+ I+G+ +F H++ + ND + NF+ G + + LF L + GW I+ D + ++ +P + N L IY SF++++ ++NM++ V++EN+++ E + Sbjct: 1134 NKFQGELYDMVQSRKFEVFIMLFITINMVVMMVQHYDHLAVWSKQ-----ILNLIFTSVFILEAILRIIAL-----RKGYFLNPWNVFDFVIVISSIIGIIVENLQTSLVINPSLL-----RVVRVFRVGRLLRFFEAARGIRRLLFSLVISTPALFNIGALLFLIIFIYAIIGMSIFG---------HVKKTEALNDVV------------NFETFGSSFVLLFRLMTSAGWNDIL----DPLMIS-EPDCDPNYRGLPSGNCGNKYMAPIYLGSFVVIIFLILINMYIAVILENYNQVMEQE 1396
BLAST of Voltage-dependent T-type calcium channel subunit alpha vs. Ensembl Medaka
Match: cacna1ha (voltage-dependent T-type calcium channel subunit alpha-1H [Source:NCBI gene;Acc:101161560]) HSP 1 Score: 645.195 bits (1663), Expect = 0.000e+0 Identity = 393/617 (63.70%), Postives = 482/617 (78.12%), Query Frame = 1 Query: 3832 SLYVFSVDNQFRQKCQHIVDKKSFDYLVLFFITLNCITLAMERPSIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKFYYCDGPHLQAVKTKNDCLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFHKCQENQXXXXXXXXXXXXXXXXXXXXXHLRAPLYWENYSKWRRTINSVVTSKYFDLAIAGVIGLNVITMATEFHMMPQVLKTALKVFNYFFTSTFVXXXXXXXXXXXXXRYISDKWNQLDMMIVILSIAGVVIDEVE-SNFMPINPTIMRVMRVLRIARVLKLLKMASGIRALLDTVIQALPQVGNXXXXXXXXXXXXXXXXVELFGRLECSDINPCVGLGRHAHFENFGMAFLTLFRIATGDNWNGIMKDTLREKCISSEDCQ---RNC-CVSAIIAPIYFVIFXXXXXXXXXXXXXXXXXKHLEESHKMMCDDYELEREVQRDLDEE 5667 SLY+F ++ FR CQ ++ K FD++VLFFI LNCIT+AMERP I PHS ERLFL+ +NYIFT+IF EM IKV++ G G Q YL+ WNI+DG LVF+SLLD+ ++I N+I G+LRV RLLRTLRPLRVISRAPGLKLVV+TL++SLRPIGNIVLICCTFFI+FGILGVQLFKGKFY C+G + V K+DCL+ + W N+KYNFDNL +ALM+LFVLS KDGWV IMY G+DAVGV+ QP NHN W LIYFISFLL+V+FFVLNMFVGVVVENFHKC+++QE+EE R KR + ++KKR+ Y+ +YS R I+ + T+ Y DL I ++G+N++TM+ E + Q LK ALK NY FT F +EALLKLVA G+ R+ DKWNQLD+ IV LSI G+V++E+ +PINPTI+R+MRVLRIARVLKLLKMA G+RALLDTV+QALPQVGNLGLLF LLF+I+AALGVELFG+L+C+DINPC GL RHA FENFGMAFLTLFR++TGDNW+GIMKDTLRE CQ RNC A ++P YFV FVL+AQFVLVNVVVAVLMKHLEES+K +D E++ E+ +++ E Sbjct: 1144 SLYLFDPESWFRSCCQRVISHKLFDHVVLFFIFLNCITIAMERPDIKPHSLERLFLSASNYIFTVIFLIEMAIKVVALGFCFGKQCYLQCSWNILDGLLVFVSLLDVLVSIAYVGENKILGVLRVLRLLRTLRPLRVISRAPGLKLVVETLITSLRPIGNIVLICCTFFIVFGILGVQLFKGKFYICEGFDTRNVTNKSDCLQ-ANYRWTNRKYNFDNLFKALMSLFVLSCKDGWVNIMYDGLDAVGVDQQPVRNHNPWMLIYFISFLLIVSFFVLNMFVGVVVENFHKCRQDQEEEEARLREDKRQKMIDKKRRRAMQRPYYADYSPVRLYIHRLCTNHYLDLFITLIVGINILTMSVEHYNQQQYLKEALKDCNYVFTFIFFVEALLKLVAFGIHRFFKDKWNQLDVAIVALSILGIVLEELNMKGALPINPTIIRIMRVLRIARVLKLLKMAKGMRALLDTVMQALPQVGNLGLLFMLLFFIYAALGVELFGKLKCTDINPCEGLSRHATFENFGMAFLTLFRVSTGDNWSGIMKDTLRE-------CQPDDRNCFAYLAWVSPFYFVTFVLIAQFVLVNVVVAVLMKHLEESNKEAKEDAEMDAEIALEMERE 1752 HSP 2 Score: 335.109 bits (858), Expect = 4.562e-92 Identity = 204/383 (53.26%), Postives = 267/383 (69.71%), Query Frame = 1 Query: 418 MTIIAVNCITLSMYQPCGDQNCETSKCQIMQAFDYIIFAFFTCEMVIKIIAMGFLGDLGYFGDTWNRLDMFIVIVGSIEILPSTGNNIGLTAIRTIRVLRPLRAINRIPSMRIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQMWQGVLRNRCYLNLNESFRHPGLNLSSFYQINRTLFLNAVDKDFICSTDKNNGILKCSDIPPSIMLLSNNSLQICKQPARPFT--DNLP--TKHSCVNWNQYYTDCQPGEKNPYEGAINFDNIGFAWVAIFQVISMESWVDIMYYVQDAHSFWDWIYFVALIIIGSFFMINLCLVVIASQFSETKRRETERMWIERRRFNSSNCSSISKDEPQTCYLEXXXXXXXXXXXXYRRIVKLY 1554 M +I +NC+TL M+QPC D +C + +C+++Q D IFAFF EMVIK++A G G Y D WN+LD IV+ G +E G N L+AIRT+RVLRPLRAINR+PSMRILV LLLDTLPMLGNVL LCFFVFFIFGI+GVQ+W G+LRNRC+L + + +L +Y D FICST + NG+L C D+PPS SL +Q + D++ + + CVNWNQYY C GE NP++GA+NFDNIG+A +AIFQVI++E WVDIMY+V DAHSF+++IYF+ LII+GSFFMINLCLVVIA+QFSETK+RE M +R R+ SS+ + S EP +CY EI++ I+ + K+ RR+ ++Y Sbjct: 1 MMVILLNCVTLGMFQPCEDVDCLSERCKVLQVLDDCIFAFFAVEMVIKMMAFGVFGSKCYLADRWNQLDFVIVMAGMLE-YSLDGQNASLSAIRTVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLFLCFFVFFIFGIVGVQLWAGLLRNRCFLGEDTKVLY-NQSLKPYYVDEE-----GEDNPFICSTPRENGMLHCYDVPPSTEDGVECSLTASQQSSVLIGSFDSVAGASVNGCVNWNQYYNVCHAGEFNPHKGAVNFDNIGYASIAIFQVITLEGWVDIMYFVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQRENALMREQRARYMSSDSTFSSYTEPGSCYEEILRYISHLYRKLRRRLQRIY 376 HSP 3 Score: 318.546 bits (815), Expect = 6.308e-87 Identity = 179/315 (56.83%), Postives = 227/315 (72.06%), Query Frame = 1 Query: 2155 QQKIKTLVNDVKFQRGILIAILINTLSMGIEYHQQPVQLTQTLEFSNIVFSILFLIEMILKLIGEGILGYIKNGFNLFDGIIVVLGVIELCQQGGTSGLSILRTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKF-CTIENNKRTCDRKNFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTSSWAALYFIALMTFGNYVLFNLLVAILVEGFSSERLDEQKLLHNYRQSLKKRRANNKQLRIMQHQSENLVL-LTNSIQKDQTGENQKISSQPPVIIHTAATPMPTPRSS 3093 ++ ++T+V F + I+ AILINT SMGIEYH+QP LTQ LE +N VF+ +F++EM L+ G+ GYIKN +N+FD ++V++ V E+ Q GLS+LRTFRLLR+LKLVRFMPALR+QL V+++T+DNVATF LL+LFIF FSILGM LFGCKF +EN DRKNFDSLLW+IVTVFQILTQEDWN VLYNGM TS WAALYF+ALMTFGNYVLFNLLVAILVEGF +E N +S +++++N Q ++ L +T + D G ++ PP+I+ TAATPMPTP SS Sbjct: 645 RETLRTIVESKYFNQAIMTAILINTFSMGIEYHEQPEYLTQVLEITNFVFTSIFVLEMGFMLLAFGLWGYIKNPYNIFDSVVVIISVWEISAQA-DGGLSVLRTFRLLRVLKLVRFMPALRRQLVVLMKTMDNVATFCMLLMLFIFTFSILGMHLFGCKFGLRLENGDTIPDRKNFDSLLWAIVTVFQILTQEDWNVVLYNGMASTSPWAALYFVALMTFGNYVLFNLLVAILVEGFQAEG------DANRSESDDEKKSDNSDEDEKLEQFTDIELEMTANGHIDACG-----TTAPPIIMRTAATPMPTPTSS 947 HSP 4 Score: 107.071 bits (266), Expect = 1.672e-22 Identity = 77/292 (26.37%), Postives = 141/292 (48.29%), Query Frame = 1 Query: 3832 SLYVFSVDNQ----FRQKCQHIVDKKSFDYLVLFFITLNCITLAMERPSIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKFYYCDGPHLQAVKTKNDCLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFH 4695 S +VFS FR+ + IV+ K F+ ++ I +N ++ +E P + + L +TN++FT IF EM +L+ GL Y+K+ +NI D +V IS+ ++ ++ +LR FRLLR L+ +R + P L+ + L+ ++ + ++ F F ILG+ LF KF G L+ T D + NFD+L A++ +F + +++ W ++Y G+ + + WA +YF++ + + + N+ V ++VE F Sbjct: 630 SKFVFSKAGHAWKNFRETLRTIVESKYFNQAIMTAILINTFSMGIEYHEQPEYLTQ--VLEITNFVFTSIFVLEMGFMLLAFGLW----GYIKNPYNIFDSVVVIISVWEIS-----AQADGGLSVLRTFRLLRVLKLVRFM---PALRRQLVVLMKTMDNVATFCMLLMLFIFTFSILGMHLFGCKF----GLRLENGDTIPD------------RKNFDSLLWAIVTVFQILTQEDWNVVLYNGMAST----------SPWAALYFVALMTFGNYVLFNLLVAILVEGFQ 881 HSP 5 Score: 87.0409 bits (214), Expect = 2.275e-16 Identity = 71/228 (31.14%), Postives = 119/228 (52.19%), Query Frame = 1 Query: 4783 RAPLYWENYSKWRRTINSVVTSKYFDLAIAGVIGLNVITMATEFHMMPQVLKTALKVFNYFFTSTFVXXXXXXXXXXXXXRYISDKWNQLDMMIVILSIAGVVIDEVESNFMPINPTIMRVMRVLRIARVLKLLKMASGIRALLDTVIQALPQVGNXXXXXXXXXXXXXXXXVELFG-----RLECSDINPCVGLGRHAHFENFGMAFLTLFRIATGDNWNGIMKDTL 5451 +A W+N+ R T+ ++V SKYF+ AI I +N +M E+H P+ L L++ N+ FTS FVLE L+A GL YI + +N D ++VI+S+ + + V+R R+ RVLKL++ +R L +++ + V +L L + F+ LG+ LFG RLE D P +F++ A +T+F+I T ++WN ++ + + Sbjct: 636 KAGHAWKNF---RETLRTIVESKYFNQAIMTAILINTFSMGIEYHEQPEYLTQVLEITNFVFTSIFVLEMGFMLLAFGLWGYIKNPYNIFDSVVVIISVWEISAQADGG---------LSVLRTFRLLRVLKLVRFMPALRRQLVVLMKTMDNVATFCMLLMLFIFTFSILGMHLFGCKFGLRLENGDTIP-----DRKNFDSLLWAIVTVFQILTQEDWNVVLYNGM 846 HSP 6 Score: 81.2629 bits (199), Expect = 1.155e-14 Identity = 61/223 (27.35%), Postives = 116/223 (52.02%), Query Frame = 1 Query: 2203 ILIAILINTLSMGIEYHQQPVQLTQTLEFSNIVFSILFLIEMILKLIGEGILGYIKNGFNLFDGIIVVLGVI-----ELCQQGG----TSGLSILRTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKFCTIENNKRTCDR-KNFDSLLWSIVTVFQILTQEDWNTVLYNGMTRT-----SSWAALYFIALMTFGNYVL 2826 I + + IN L+M +E++ Q L + L+ N VF+ +F +E +LKL+ GI + K+ +N D IV L ++ EL +G + + I+R R+ R+LKL++ +R L +++ + V L +L FI++ LG+ LFG CT N R F++ + +T+F++ T ++W+ ++ + + + +A L +++ F +VL Sbjct: 1488 ITLIVGINILTMSVEHYNQQQYLKEALKDCNYVFTFIFFVEALLKLVAFGIHRFFKDKWNQLDVAIVALSILGIVLEELNMKGALPINPTIIRIMRVLRIARVLKLLKMAKGMRALLDTVMQALPQVGNLGLLFMLLFFIYAALGVELFGKLKCTDINPCEGLSRHATFENFGMAFLTLFRVSTGDNWSGIMKDTLRECQPDDRNCFAYLAWVSPFYFVTFVL 1710 HSP 7 Score: 76.6406 bits (187), Expect = 3.066e-13 Identity = 77/312 (24.68%), Postives = 151/312 (48.40%), Query Frame = 1 Query: 2140 YLSICQQKIKTLVNDVKFQRGILIAILINTLSMGIEYHQ-QPVQLTQT-LEFSNIVFSILFLIEMILKLIGEGIL----GYIKNGFNLFDGIIVVLGVIELCQQGGTSG-------LSILRTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKFCTIEN-------NKRTC--------DRK-NFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTS----------SWAALYFIALMTFGNYVLFNLLVAILVEGFSSERLDEQKLLHNYRQSLKKRRANNKQLRIMQ 2958 + S CQ+ I + F +L I +N +++ +E +P L + L SN +F+++FLIEM +K++ G Y++ +N+ DG++V + ++++ G L +LR R LR L+++ P L+ + +I ++ + + F +F ILG+ LF KF E NK C +RK NFD+L +++++F + ++ W ++Y+G+ W +YFI+ + ++ + N+ V ++VE F R D+++ R+ +++ + K+ R MQ Sbjct: 1154 FRSCCQRVISHKL----FDHVVLFFIFLNCITIAMERPDIKPHSLERLFLSASNYIFTVIFLIEMAIKVVALGFCFGKQCYLQCSWNILDGLLVFVSLLDVLVSIAYVGENKILGVLRVLRLLRTLRPLRVISRAPGLKLVVETLITSLRPIGNIVLICCTFFIVFGILGVQLFKGKFYICEGFDTRNVTNKSDCLQANYRWTNRKYNFDNLFKALMSLFVLSCKDGWVNIMYDGLDAVGVDQQPVRNHNPWMLIYFISFLLIVSFFVLNMFVGVVVENFHKCRQDQEEEEARLREDKRQKMIDKKRRRAMQ 1461 HSP 8 Score: 63.5438 bits (153), Expect = 3.077e-9 Identity = 54/156 (34.62%), Postives = 86/156 (55.13%), Query Frame = 1 Query: 3916 LFFITLNCITLAMERP--SIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKG 4377 + I LNC+TL M +P + S+ L V + F EM+IK+++ G+ G + YL WN +D +V +L+ + G + + I R +R LRPLR I+R P ++++V LL +L +GN++ +C F IFGI+GVQL+ G Sbjct: 1 MMVILLNCVTLGMFQPCEDVDCLSERCKVLQVLDDCIFAFFAVEMVIKMMAFGVF-GSKCYLADRWNQLDFVIVMAGMLEYSLD---GQNASLSAI----RTVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLFLCFFVFFIFGIVGVQLWAG 148 HSP 9 Score: 58.5362 bits (140), Expect = 1.105e-7 Identity = 34/111 (30.63%), Postives = 58/111 (52.25%), Query Frame = 1 Query: 337 FHIFHQNKHPRDWCLKIITWPWFEQLSMTIIAVNCITLSMYQPCGDQNCETSKCQIMQAFDYIIFAFFTCEMVIKIIAMGF-LGDLGYFGDTWNRLDMFIVIVGSIEILPS 666 ++F R C ++I+ F+ + + I +NCIT++M +P D + + + A +YI F EM IK++A+GF G Y +WN LD +V V +++L S Sbjct: 1145 LYLFDPESWFRSCCQRVISHKLFDHVVLFFIFLNCITIAMERP--DIKPHSLERLFLSASNYIFTVIFLIEMAIKVVALGFCFGKQCYLQCSWNILDGLLVFVSLLDVLVS 1253 HSP 10 Score: 53.9138 bits (128), Expect = 2.394e-6 Identity = 32/110 (29.09%), Postives = 59/110 (53.64%), Query Frame = 1 Query: 4411 AVKTKNDCLKYSQ-------NEWKNQK--YNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFHKCQENQ 4713 A + N C+ ++Q E+ K NFDN+G A +A+F + + +GWV IMY +DA H+ + IYFI +++ +FF++N+ + V+ F + ++ + Sbjct: 227 AGASVNGCVNWNQYYNVCHAGEFNPHKGAVNFDNIGYASIAIFQVITLEGWVDIMYFVMDA----------HSFYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQRE 326 HSP 11 Score: 52.7582 bits (125), Expect = 5.016e-6 Identity = 32/114 (28.07%), Postives = 58/114 (50.88%), Query Frame = 1 Query: 1099 TDNLPTKHSCVNWNQYYTDCQPGEKNPYEGAINFDNIGFAWVAIFQVISMESWVDIMYYVQDA----------HSFWDWIYFVALIIIGSFFMINLCLVVIASQFSETKRRETE 1410 T N+ K C+ N +T+ + NFDN+ A +++F + + WV+IMY DA H+ W IYF++ ++I SFF++N+ + V+ F + ++ + E Sbjct: 1335 TRNVTNKSDCLQANYRWTNRK----------YNFDNLFKALMSLFVLSCKDGWVNIMYDGLDAVGVDQQPVRNHNPWMLIYFISFLLIVSFFVLNMFVGVVVENFHKCRQDQEE 1438 HSP 12 Score: 52.373 bits (124), Expect = 7.572e-6 Identity = 23/78 (29.49%), Postives = 44/78 (56.41%), Query Frame = 1 Query: 2674 NFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTSSWAALYFIALMTFGNYVLFNLLVAILVEGFSSERLDEQKLLHNYR 2907 NFD++ ++ + +FQ++T E W ++Y M S + +YFI L+ G++ + NL + ++ FS + E L+ R Sbjct: 257 NFDNIGYASIAIFQVITLEGWVDIMYFVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQRENALMREQR 334 HSP 13 Score: 52.373 bits (124), Expect = 7.897e-6 Identity = 23/75 (30.67%), Postives = 44/75 (58.67%), Query Frame = 1 Query: 1195 NFDNIGFAWVAIFQVISMESWVDIMYYVQDAHSFWDWIYFVALIIIGSFFMINLCLVVIASQF---SETKRRETE 1410 NFD++ +A V +FQ+++ E W ++Y + S W +YFVAL+ G++ + NL + ++ F + R E++ Sbjct: 818 NFDSLLWAIVTVFQILTQEDWNVVLYNGMASTSPWAALYFVALMTFGNYVLFNLLVAILVEGFQAEGDANRSESD 892
BLAST of Voltage-dependent T-type calcium channel subunit alpha vs. Ensembl Medaka
Match: cacna1ha (voltage-dependent T-type calcium channel subunit alpha-1H [Source:NCBI gene;Acc:101161560]) HSP 1 Score: 644.81 bits (1662), Expect = 0.000e+0 Identity = 393/617 (63.70%), Postives = 482/617 (78.12%), Query Frame = 1 Query: 3832 SLYVFSVDNQFRQKCQHIVDKKSFDYLVLFFITLNCITLAMERPSIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKFYYCDGPHLQAVKTKNDCLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFHKCQENQXXXXXXXXXXXXXXXXXXXXXHLRAPLYWENYSKWRRTINSVVTSKYFDLAIAGVIGLNVITMATEFHMMPQVLKTALKVFNYFFTSTFVXXXXXXXXXXXXXRYISDKWNQLDMMIVILSIAGVVIDEVE-SNFMPINPTIMRVMRVLRIARVLKLLKMASGIRALLDTVIQALPQVGNXXXXXXXXXXXXXXXXVELFGRLECSDINPCVGLGRHAHFENFGMAFLTLFRIATGDNWNGIMKDTLREKCISSEDCQ---RNC-CVSAIIAPIYFVIFXXXXXXXXXXXXXXXXXKHLEESHKMMCDDYELEREVQRDLDEE 5667 SLY+F ++ FR CQ ++ K FD++VLFFI LNCIT+AMERP I PHS ERLFL+ +NYIFT+IF EM IKV++ G G Q YL+ WNI+DG LVF+SLLD+ ++I N+I G+LRV RLLRTLRPLRVISRAPGLKLVV+TL++SLRPIGNIVLICCTFFI+FGILGVQLFKGKFY C+G + V K+DCL+ + W N+KYNFDNL +ALM+LFVLS KDGWV IMY G+DAVGV+ QP NHN W LIYFISFLL+V+FFVLNMFVGVVVENFHKC+++QE+EE R KR + ++KKR+ Y+ +YS R I+ + T+ Y DL I ++G+N++TM+ E + Q LK ALK NY FT F +EALLKLVA G+ R+ DKWNQLD+ IV LSI G+V++E+ +PINPTI+R+MRVLRIARVLKLLKMA G+RALLDTV+QALPQVGNLGLLF LLF+I+AALGVELFG+L+C+DINPC GL RHA FENFGMAFLTLFR++TGDNW+GIMKDTLRE CQ RNC A ++P YFV FVL+AQFVLVNVVVAVLMKHLEES+K +D E++ E+ +++ E Sbjct: 1092 SLYLFDPESWFRSCCQRVISHKLFDHVVLFFIFLNCITIAMERPDIKPHSLERLFLSASNYIFTVIFLIEMAIKVVALGFCFGKQCYLQCSWNILDGLLVFVSLLDVLVSIAYVGENKILGVLRVLRLLRTLRPLRVISRAPGLKLVVETLITSLRPIGNIVLICCTFFIVFGILGVQLFKGKFYICEGFDTRNVTNKSDCLQ-ANYRWTNRKYNFDNLFKALMSLFVLSCKDGWVNIMYDGLDAVGVDQQPVRNHNPWMLIYFISFLLIVSFFVLNMFVGVVVENFHKCRQDQEEEEARLREDKRQKMIDKKRRRAMQRPYYADYSPVRLYIHRLCTNHYLDLFITLIVGINILTMSVEHYNQQQYLKEALKDCNYVFTFIFFVEALLKLVAFGIHRFFKDKWNQLDVAIVALSILGIVLEELNMKGALPINPTIIRIMRVLRIARVLKLLKMAKGMRALLDTVMQALPQVGNLGLLFMLLFFIYAALGVELFGKLKCTDINPCEGLSRHATFENFGMAFLTLFRVSTGDNWSGIMKDTLRE-------CQPDDRNCFAYLAWVSPFYFVTFVLIAQFVLVNVVVAVLMKHLEESNKEAKEDAEMDAEIALEMERE 1700 HSP 2 Score: 335.109 bits (858), Expect = 4.629e-92 Identity = 204/383 (53.26%), Postives = 267/383 (69.71%), Query Frame = 1 Query: 418 MTIIAVNCITLSMYQPCGDQNCETSKCQIMQAFDYIIFAFFTCEMVIKIIAMGFLGDLGYFGDTWNRLDMFIVIVGSIEILPSTGNNIGLTAIRTIRVLRPLRAINRIPSMRIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQMWQGVLRNRCYLNLNESFRHPGLNLSSFYQINRTLFLNAVDKDFICSTDKNNGILKCSDIPPSIMLLSNNSLQICKQPARPFT--DNLP--TKHSCVNWNQYYTDCQPGEKNPYEGAINFDNIGFAWVAIFQVISMESWVDIMYYVQDAHSFWDWIYFVALIIIGSFFMINLCLVVIASQFSETKRRETERMWIERRRFNSSNCSSISKDEPQTCYLEXXXXXXXXXXXXYRRIVKLY 1554 M +I +NC+TL M+QPC D +C + +C+++Q D IFAFF EMVIK++A G G Y D WN+LD IV+ G +E G N L+AIRT+RVLRPLRAINR+PSMRILV LLLDTLPMLGNVL LCFFVFFIFGI+GVQ+W G+LRNRC+L + + +L +Y D FICST + NG+L C D+PPS SL +Q + D++ + + CVNWNQYY C GE NP++GA+NFDNIG+A +AIFQVI++E WVDIMY+V DAHSF+++IYF+ LII+GSFFMINLCLVVIA+QFSETK+RE M +R R+ SS+ + S EP +CY EI++ I+ + K+ RR+ ++Y Sbjct: 1 MMVILLNCVTLGMFQPCEDVDCLSERCKVLQVLDDCIFAFFAVEMVIKMMAFGVFGSKCYLADRWNQLDFVIVMAGMLE-YSLDGQNASLSAIRTVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLFLCFFVFFIFGIVGVQLWAGLLRNRCFLGEDTKVLY-NQSLKPYYVDE-----EGEDNPFICSTPRENGMLHCYDVPPSTEDGVECSLTASQQSSVLIGSFDSVAGASVNGCVNWNQYYNVCHAGEFNPHKGAVNFDNIGYASIAIFQVITLEGWVDIMYFVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQRENALMREQRARYMSSDSTFSSYTEPGSCYEEILRYISHLYRKLRRRLQRIY 376 HSP 3 Score: 201.83 bits (512), Expect = 2.959e-51 Identity = 112/188 (59.57%), Postives = 144/188 (76.60%), Query Frame = 1 Query: 2155 QQKIKTLVNDVKFQRGILIAILINTLSMGIEYHQQPVQLTQTLEFSNIVFSILFLIEMILKLIGEGILGYIKNGFNLFDGIIVVLGVIELCQQGGTSGLSILRTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKF-CTIENNKRTCDRKNFDSLLWSIVTVFQ 2715 ++ ++T+V F + I+ AILINT SMGIEYH+QP LTQ LE +N VF+ +F++EM L+ G+ GYIKN +N+FD ++V++ V E+ Q GLS+LRTFRLLR+LKLVRFMPALR+QL V+++T+DNVATF LL+LFIF FSILGM LFGCKF +EN DRKNFDSLLW+IVTVFQ Sbjct: 645 RETLRTIVESKYFNQAIMTAILINTFSMGIEYHEQPEYLTQVLEITNFVFTSIFVLEMGFMLLAFGLWGYIKNPYNIFDSVVVIISVWEISAQ-ADGGLSVLRTFRLLRVLKLVRFMPALRRQLVVLMKTMDNVATFCMLLMLFIFTFSILGMHLFGCKFGLRLENGDTIPDRKNFDSLLWAIVTVFQ 831 HSP 4 Score: 81.2629 bits (199), Expect = 1.140e-14 Identity = 61/223 (27.35%), Postives = 115/223 (51.57%), Query Frame = 1 Query: 2203 ILIAILINTLSMGIEYHQQPVQLTQTLEFSNIVFSILFLIEMILKLIGEGILGYIKNGFNLFDGIIVVLGVI-----ELCQQGG----TSGLSILRTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKFCTIENNKRTCDR-KNFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTSS-----WAALYFIALMTFGNYVL 2826 I + + IN L+M +E++ Q L + L+ N VF+ +F +E +LKL+ GI + K+ +N D IV L ++ EL +G + + I+R R+ R+LKL++ +R L +++ + V L +L FI++ LG+ LFG CT N R F++ + +T+F++ T ++W+ ++ + + +A L +++ F +VL Sbjct: 1436 ITLIVGINILTMSVEHYNQQQYLKEALKDCNYVFTFIFFVEALLKLVAFGIHRFFKDKWNQLDVAIVALSILGIVLEELNMKGALPINPTIIRIMRVLRIARVLKLLKMAKGMRALLDTVMQALPQVGNLGLLFMLLFFIYAALGVELFGKLKCTDINPCEGLSRHATFENFGMAFLTLFRVSTGDNWSGIMKDTLRECQPDDRNCFAYLAWVSPFYFVTFVL 1658 HSP 5 Score: 79.7221 bits (195), Expect = 3.373e-14 Identity = 65/231 (28.14%), Postives = 111/231 (48.05%), Query Frame = 1 Query: 3832 SLYVFSVDNQ----FRQKCQHIVDKKSFDYLVLFFITLNCITLAMERPSIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKFYYCDGPHLQAVKTKNDCLKYSQNEWKNQKYNFDNLGQALMALF 4512 S +VFS FR+ + IV+ K F+ ++ I +N ++ +E P + + L +TN++FT IF EM +L+ GL Y+K+ +NI D +V IS+ ++ ++ +LR FRLLR L+ +R + P L+ + L+ ++ + ++ F F ILG+ LF KF G L+ T D + NFD+L A++ +F Sbjct: 630 SKFVFSKAGHAWKNFRETLRTIVESKYFNQAIMTAILINTFSMGIEYHEQPEYLTQ--VLEITNFVFTSIFVLEMGFMLLAFGLW----GYIKNPYNIFDSVVVIISVWEIS-----AQADGGLSVLRTFRLLRVLKLVRFM---PALRRQLVVLMKTMDNVATFCMLLMLFIFTFSILGMHLFGCKF----GLRLENGDTIPD------------RKNFDSLLWAIVTVF 830 HSP 6 Score: 76.6406 bits (187), Expect = 3.406e-13 Identity = 77/312 (24.68%), Postives = 151/312 (48.40%), Query Frame = 1 Query: 2140 YLSICQQKIKTLVNDVKFQRGILIAILINTLSMGIEYHQ-QPVQLTQT-LEFSNIVFSILFLIEMILKLIGEGIL----GYIKNGFNLFDGIIVVLGVIELCQQGGTSG-------LSILRTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKFCTIEN-------NKRTC--------DRK-NFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTS----------SWAALYFIALMTFGNYVLFNLLVAILVEGFSSERLDEQKLLHNYRQSLKKRRANNKQLRIMQ 2958 + S CQ+ I + F +L I +N +++ +E +P L + L SN +F+++FLIEM +K++ G Y++ +N+ DG++V + ++++ G L +LR R LR L+++ P L+ + +I ++ + + F +F ILG+ LF KF E NK C +RK NFD+L +++++F + ++ W ++Y+G+ W +YFI+ + ++ + N+ V ++VE F R D+++ R+ +++ + K+ R MQ Sbjct: 1102 FRSCCQRVISHKL----FDHVVLFFIFLNCITIAMERPDIKPHSLERLFLSASNYIFTVIFLIEMAIKVVALGFCFGKQCYLQCSWNILDGLLVFVSLLDVLVSIAYVGENKILGVLRVLRLLRTLRPLRVISRAPGLKLVVETLITSLRPIGNIVLICCTFFIVFGILGVQLFKGKFYICEGFDTRNVTNKSDCLQANYRWTNRKYNFDNLFKALMSLFVLSCKDGWVNIMYDGLDAVGVDQQPVRNHNPWMLIYFISFLLIVSFFVLNMFVGVVVENFHKCRQDQEEEEARLREDKRQKMIDKKRRRAMQ 1409 HSP 7 Score: 76.2554 bits (186), Expect = 4.347e-13 Identity = 67/213 (31.46%), Postives = 109/213 (51.17%), Query Frame = 1 Query: 4783 RAPLYWENYSKWRRTINSVVTSKYFDLAIAGVIGLNVITMATEFHMMPQVLKTALKVFNYFFTSTFVXXXXXXXXXXXXXRYISDKWNQLDMMIVILSIAGVVIDEVESNFMPINPTIMRVMRVLRIARVLKLLKMASGIRALLDTVIQALPQVGNXXXXXXXXXXXXXXXXVELFG-----RLECSDINPCVGLGRHAHFENFGMAFLTLFR 5406 +A W+N+ R T+ ++V SKYF+ AI I +N +M E+H P+ L L++ N+ FTS FVLE L+A GL YI + +N D ++VI+S+ + + V+R R+ RVLKL++ +R L +++ + V +L L + F+ LG+ LFG RLE D P +F++ A +T+F+ Sbjct: 636 KAGHAWKNF---RETLRTIVESKYFNQAIMTAILINTFSMGIEYHEQPEYLTQVLEITNFVFTSIFVLEMGFMLLAFGLWGYIKNPYNIFDSVVVIISVWEISAQADGG---------LSVLRTFRLLRVLKLVRFMPALRRQLVVLMKTMDNVATFCMLLMLFIFTFSILGMHLFGCKFGLRLENGDTIP-----DRKNFDSLLWAIVTVFQ 831 HSP 8 Score: 63.5438 bits (153), Expect = 3.336e-9 Identity = 54/156 (34.62%), Postives = 86/156 (55.13%), Query Frame = 1 Query: 3916 LFFITLNCITLAMERP--SIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKG 4377 + I LNC+TL M +P + S+ L V + F EM+IK+++ G+ G + YL WN +D +V +L+ + G + + I R +R LRPLR I+R P ++++V LL +L +GN++ +C F IFGI+GVQL+ G Sbjct: 1 MMVILLNCVTLGMFQPCEDVDCLSERCKVLQVLDDCIFAFFAVEMVIKMMAFGVF-GSKCYLADRWNQLDFVIVMAGMLEYSLD---GQNASLSAI----RTVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLFLCFFVFFIFGIVGVQLWAG 148 HSP 9 Score: 58.151 bits (139), Expect = 1.149e-7 Identity = 34/111 (30.63%), Postives = 58/111 (52.25%), Query Frame = 1 Query: 337 FHIFHQNKHPRDWCLKIITWPWFEQLSMTIIAVNCITLSMYQPCGDQNCETSKCQIMQAFDYIIFAFFTCEMVIKIIAMGF-LGDLGYFGDTWNRLDMFIVIVGSIEILPS 666 ++F R C ++I+ F+ + + I +NCIT++M +P D + + + A +YI F EM IK++A+GF G Y +WN LD +V V +++L S Sbjct: 1093 LYLFDPESWFRSCCQRVISHKLFDHVVLFFIFLNCITIAMERP--DIKPHSLERLFLSASNYIFTVIFLIEMAIKVVALGFCFGKQCYLQCSWNILDGLLVFVSLLDVLVS 1201 HSP 10 Score: 53.9138 bits (128), Expect = 2.470e-6 Identity = 32/110 (29.09%), Postives = 59/110 (53.64%), Query Frame = 1 Query: 4411 AVKTKNDCLKYSQ-------NEWKNQK--YNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFHKCQENQ 4713 A + N C+ ++Q E+ K NFDN+G A +A+F + + +GWV IMY +DA H+ + IYFI +++ +FF++N+ + V+ F + ++ + Sbjct: 227 AGASVNGCVNWNQYYNVCHAGEFNPHKGAVNFDNIGYASIAIFQVITLEGWVDIMYFVMDA----------HSFYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQRE 326 HSP 11 Score: 53.1434 bits (126), Expect = 4.838e-6 Identity = 32/114 (28.07%), Postives = 58/114 (50.88%), Query Frame = 1 Query: 1099 TDNLPTKHSCVNWNQYYTDCQPGEKNPYEGAINFDNIGFAWVAIFQVISMESWVDIMYYVQDA----------HSFWDWIYFVALIIIGSFFMINLCLVVIASQFSETKRRETE 1410 T N+ K C+ N +T+ + NFDN+ A +++F + + WV+IMY DA H+ W IYF++ ++I SFF++N+ + V+ F + ++ + E Sbjct: 1283 TRNVTNKSDCLQANYRWTNRK----------YNFDNLFKALMSLFVLSCKDGWVNIMYDGLDAVGVDQQPVRNHNPWMLIYFISFLLIVSFFVLNMFVGVVVENFHKCRQDQEE 1386 HSP 12 Score: 52.373 bits (124), Expect = 6.886e-6 Identity = 23/78 (29.49%), Postives = 44/78 (56.41%), Query Frame = 1 Query: 2674 NFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTSSWAALYFIALMTFGNYVLFNLLVAILVEGFSSERLDEQKLLHNYR 2907 NFD++ ++ + +FQ++T E W ++Y M S + +YFI L+ G++ + NL + ++ FS + E L+ R Sbjct: 257 NFDNIGYASIAIFQVITLEGWVDIMYFVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQRENALMREQR 334
BLAST of Voltage-dependent T-type calcium channel subunit alpha vs. Ensembl Medaka
Match: cacna1hb (calcium voltage-gated channel subunit alpha1 H [Source:NCBI gene;Acc:101160713]) HSP 1 Score: 639.032 bits (1647), Expect = 0.000e+0 Identity = 382/595 (64.20%), Postives = 480/595 (80.67%), Query Frame = 1 Query: 3832 SLYVFSVDNQFRQKCQHIVDKKSFDYLVLFFITLNCITLAMERPSIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKFYYCDGPHLQAVKTKNDCLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFHKCQENQXXXXXXXXXXXXXXXXXXXXXHLRAPLYWENYSKWRRTINSVVTSKYFDLAIAGVIGLNVITMATEFHMMPQVLKTALKVFNYFFTSTFVXXXXXXXXXXXXXRYISDKWNQLDMMIVILSIAGVVIDEVE-SNFMPINPTIMRVMRVLRIARVLKLLKMASGIRALLDTVIQALPQVGNXXXXXXXXXXXXXXXXVELFGRLECSDINPCVGLGRHAHFENFGMAFLTLFRIATGDNWNGIMKDTLREKCISSEDCQRNC-CVSAIIAPIYFVIFXXXXXXXXXXXXXXXXXKHLEESHK 5610 SLY+F+ DN+FR C ++ K FD++VL FI LNCIT+A+ERP I P S ER+FL+V+NYIFT+IF GEM+IKV++ GL G+ YL+S WNI+DG LVF+SL+D+ ++I NRI GILRV RLLRTLRPLRVISRAPGLKLVV+TL++SLRPIGNIVLICC FFI+FGILGVQLFKGKF++C+G H++ + + +CL+ + + W +KYNFDNLGQALM+LFVLS KDGWV IMY G+DAVGV+ QP N+N W L++FISFLL+V+FFVLNMFVGVVVENFHKC++ QE+EE R KR +RLEK+R+ Y+ +YS RR+I+++ TS Y DL I +I N++TM+ E + PQ L+ LK NY FT FV+EA+LKL+A GL R+ ++WNQLD+ IV+LSI G+ ++E++ S +PINPTI+R+MRVLRI RVLKLLKMA+G+R+LLDTV+QALPQVGNLGLLF LLF+I+AALGVELFG+LECS+ NPC GL RHA F+NFGMAFLTLFR++TGDNWNGIMKDTLRE C E R+C +I+P+YFV FVL AQFVLVNVVVAVLMKHLEES+K Sbjct: 1128 SLYLFAPDNRFRLWCLRVIGHKMFDHIVLLFIFLNCITIALERPDISPRSMERVFLSVSNYIFTVIFVGEMMIKVVAMGLYFGEGVYLQSSWNILDGVLVFVSLVDILVSIASSGGNRILGILRVLRLLRTLRPLRVISRAPGLKLVVETLITSLRPIGNIVLICCAFFIVFGILGVQLFKGKFFHCEGLHVRNITNRTECLQ-AGHRWVRRKYNFDNLGQALMSLFVLSCKDGWVSIMYDGLDAVGVDQQPIRNNNPWMLLFFISFLLIVSFFVLNMFVGVVVENFHKCRQQQEEEEARIREEKRQKRLEKRRRRALEKPYYADYSPLRRSIHTLCTSHYLDLFITVIIFTNLLTMSMEHYNQPQYLEEILKYCNYVFTLVFVIEAILKLIAFGLRRFFKERWNQLDLAIVLLSIMGIALEEIDLSASLPINPTIIRIMRVLRITRVLKLLKMATGMRSLLDTVMQALPQVGNLGLLFMLLFFIYAALGVELFGKLECSEENPCEGLSRHATFDNFGMAFLTLFRVSTGDNWNGIMKDTLRE-CRPHE---RHCLSYLPLISPVYFVTFVLTAQFVLVNVVVAVLMKHLEESNK 1717 HSP 2 Score: 375.17 bits (962), Expect = 2.096e-104 Identity = 223/424 (52.59%), Postives = 294/424 (69.34%), Query Frame = 1 Query: 307 LIYHGFYATVFHIFHQNKHPRDWCLKIITWPWFEQLSMTIIAVNCITLSMYQPCGDQNCETSKCQIMQAFDYIIFAFFTCEMVIKIIAMGFLGDLGYFGDTWNRLDMFIVIVGSIEILPSTGNNIGLTAIRTIRVLRPLRAINRIPSMRIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQMWQGVLRNRCYLNLNESFRHPGLNLSSFYQINRTLFLNAVDKDFICSTDKNNGILKCSDIPPSIMLLSNNSLQICKQPARPFTDNLPTKHSCVNWNQYYTDCQPGEKNPYEGAINFDNIGFAWVAIFQVISMESWVDIMYYVQDAHSFWDWIYFVALIIIGSFFMINLCLVVIASQFSETKRRETERMWIER--RRFNSSNCSSISKDEPQTCYLEXXXXXXXXXXXXYRRIVKLYNQIQIR 1572 L Y V Q PR WCL+ + PWFE++S+ I +NC+TL M+QPCG ++QA D IFAFF EMV+K++A+G +G GY GDTWNRLD FIVIVG +E G+N+ L+AIRT+RVLRPLRAINR+PSMRILV LLLDTLPMLGNVL LCFFVFFIFGI+GVQ+W G+LRNRC++ + R+ L+ +Y+ + T D FICST + NG+L+CSD+P + ++ +L + + ++ SCVNW Q+Y C+ GE NP++GAINFDNIG+AW+AIFQVI++E WVDIMYYV DAHSF+++IYF+ LII+GSFFMINLCLVVIA+QFSETK+RE M E+ R+ + S + S +P +CY EII+ + + K +RRI + Y+QI R Sbjct: 58 LPYPSLAPVVLLALTQTSPPRSWCLRAVCHPWFERVSILAILLNCVTLGMFQPCGHTP------SVLQALDDGIFAFFAGEMVVKMVALGVIGQKGYLGDTWNRLDFFIVIVGMLE-YSLDGHNVSLSAIRTVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLALCFFVFFIFGIVGVQLWAGLLRNRCFIEEDVKMRYNITFLNDYYKPDGT-----DDHPFICSTARENGMLRCSDVPRRRVGRTHCNLDADEAFSETGLKGDESE-SCVNWYQFYNQCRAGELNPHKGAINFDNIGYAWIAIFQVITLEGWVDIMYYVMDAHSFYNFIYFIFLIIVGSFFMINLCLVVIATQFSETKQREHALMKSEQRARQLHQSASTLASDSQPGSCYEEIIRYLAHLGRKAWRRISRCYSQIWRR 468 HSP 3 Score: 290.812 bits (743), Expect = 2.209e-78 Identity = 181/311 (58.20%), Postives = 222/311 (71.38%), Query Frame = 1 Query: 2161 KIKTLVNDVKFQRGILIAILINTLSMGIEYHQQPVQLTQTLEFSNIVFSILFLIEMILKLIGEGILGYIKNGFNLFDGIIVVLGVIELCQQGGTSGLSILRTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKFCTIENNKRTC-DRKNFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTSSWAALYFIALMTFGNYVLFNLLVAILVEGFSSE------RLDEQKLLHNYRQSLKKRRANNKQLRIMQHQSENLVLLTNSIQKDQTGENQKISSQPPVIIHTAATP 3072 K+K +V+ F RGI+IAILINTLSMGIEYH+QP +LT LE SN+VF+ LF +EM+LKL+ G+ GYIKN +N FD IIV++ V E+ Q GLS+LRTFRLLR+LKLVRF+PALR+QL V+++T+DNVATF LL+LFIFIFSILGM LFGCKF +++ T DRKNFDSLLW+ VTVFQILTQEDWN VLYNGM TS AALYF+ALMTFGNYVLFNLLVAILVEGF +E D+ +L Y K + +L+I + ++L N + + PVI HTAATP Sbjct: 674 KLKLIVSSRYFNRGIMIAILINTLSMGIEYHEQPQELTDILEISNMVFTSLFSLEMLLKLLALGLFGYIKNPYNGFDSIIVIISVWEIVGQA-EGGLSVLRTFRLLRVLKLVRFLPALRRQLVVLMKTMDNVATFCMLLMLFIFIFSILGMHLFGCKFGLRQDSGDTLPDRKNFDSLLWATVTVFQILTQEDWNAVLYNGMASTSPLAALYFVALMTFGNYVLFNLLVAILVEGFQAEGDANRSEADDDRLSLCYHDEEKLKELYAAELKI-----QAMMLSPNGLLNPKASMPPPPPPPLPVITHTAATP 978 HSP 4 Score: 92.8189 bits (229), Expect = 4.082e-18 Identity = 71/259 (27.41%), Postives = 129/259 (49.81%), Query Frame = 1 Query: 2104 FNKNQNKTKRKNYL---SICQQKIKTLVNDVKFQRGILIAILINTLSMGIEYHQQPVQLTQTLEFSNIVFSILFLIEMILKLIGEGILGYIKNGFNLFDGIIVVLGVIELCQQG---------GTSGLSILRTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKFCTIENNKRTCDR-KNFDSLLWSIVTVFQILTQEDWNTVLYNGM--TRTSSWAALYFIALMTFGNYVLFNL 2835 K + + K Y S ++ I TL I + I N L+M +E++ QP L + L++ N VF+++F+IE ILKLI G+ + K +N D IV+L ++ + + + + I+R R+ R+LKL++ +R L +++ + V L +L FI++ LG+ LFG C+ EN R FD+ + +T+F++ T ++WN ++ + + R L ++ L++ +V F L Sbjct: 1436 LEKRRRRALEKPYYADYSPLRRSIHTLCTSHYLDLFITVIIFTNLLTMSMEHYNQPQYLEEILKYCNYVFTLVFVIEAILKLIAFGLRRFFKERWNQLDLAIVLLSIMGIALEEIDLSASLPINPTIIRIMRVLRITRVLKLLKMATGMRSLLDTVMQALPQVGNLGLLFMLLFFIYAALGVELFGKLECSEENPCEGLSRHATFDNFGMAFLTLFRVSTGDNWNGIMKDTLRECRPHERHCLSYLPLISPVYFVTFVL 1694 HSP 5 Score: 86.2705 bits (212), Expect = 3.735e-16 Identity = 89/390 (22.82%), Postives = 170/390 (43.59%), Query Frame = 1 Query: 3550 MAYKNKINQLTIPF---SNRYSLSLDSEGKSN-----YQFKMNYLLAREKALEEPDDSNSESQNSSRMNNVEDPDEEDMEAMICLSKC-CPQPKGIFAKRYYHSLYVFSVDNQFRQKCQHIVDKKSFDYLVLFFITLNCITLAMERPSIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKFYYCDGPHLQAVKTKNDCLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENF 4692 M N++ QL + + +L L EG Y + L E E P++ + QNS N+ + C +P+ +R + L R K + IV + F+ ++ I +N +++ +E P + L ++N +FT +F+ EM++K+L+ GL Y+K+ +N D +V IS+ + ++G + +LR FRLLR L+ +R + P L+ + L+ ++ + ++ F IF ILG+ LF KF L+ + + NFD+L A + +F + +++ W ++Y G+ + + A +YF++ + + + N+ V ++VE F Sbjct: 567 METINRLPQLVLEHGGSAGHPALQLPGEGSGEASSCPYCTYYSQLSGSENLHEHPEEQHHRYQNSRLGNHPCHGNSPCQSRSPCYGNAQVLEPRKKLWERCWAGL---------RIKLKLIVSSRYFNRGIMIAILINTLSMGIEYHEQPQELTD--ILEISNMVFTSLFSLEMLLKLLALGLF----GYIKNPYNGFDSIIVIISVWE-----IVGQAEGGLSVLRTFRLLRVLKLVRFL---PALRRQLVVLMKTMDNVATFCMLLMLFIFIFSILGMHLFGCKF----------------GLRQDSGDTLPDRKNFDSLLWATVTVFQILTQEDWNAVLYNGMAST----------SPLAALYFVALMTFGNYVLFNLLVAILVEGF 907 HSP 6 Score: 85.5001 bits (210), Expect = 6.032e-16 Identity = 61/171 (35.67%), Postives = 98/171 (57.31%), Query Frame = 1 Query: 3865 RQKCQHIVDKKSFDYLVLFFITLNCITLAMERPSIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKG 4377 R C V F+ + + I LNC+TL M +P H+ + + + IF F GEM++K+++ G+ IG + YL WN +D F+V + +L+ + GH+ + I R +R LRPLR I+R P ++++V LL +L +GN++ +C F IFGI+GVQL+ G Sbjct: 78 RSWCLRAVCHPWFERVSILAILLNCVTLGMFQPC--GHTPS-VLQALDDGIFAF-FAGEMVVKMVALGV-IGQKGYLGDTWNRLDFFIVIVGMLEYSLD---GHNVSLSAI----RTVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLALCFFVFFIFGIVGVQLWAG 236 HSP 7 Score: 78.1814 bits (191), Expect = 1.236e-13 Identity = 73/224 (32.59%), Postives = 121/224 (54.02%), Query Frame = 1 Query: 4798 WEN-YSKWRRTINSVVTSKYFDLAIAGVIGLNVITMATEFHMMPQVLKTALKVFNYFFTSTFVXXXXXXXXXXXXXRYISDKWNQLDMMIVILSIAGVVIDEVESNFMPINPTIMRVMRVLRIARVLKLLKMASGIRALLDTVIQALPQVGNXXXXXXXXXXXXXXXXVELFG-----RLECSDINPCVGLGRHAHFENFGMAFLTLFRIATGDNWNGIMKDTL 5451 WE ++ R + +V+S+YF+ I I +N ++M E+H PQ L L++ N FTS F LE LLKL+ALGL YI + +N D +IVI+S+ +V + E + V+R R+ RVLKL++ +R L +++ + V +L L +IF+ LG+ LFG R + D P +F++ A +T+F+I T ++WN ++ + + Sbjct: 664 WERCWAGLRIKLKLIVSSRYFNRGIMIAILINTLSMGIEYHEQPQELTDILEISNMVFTSLFSLEMLLKLLALGLFGYIKNPYNGFDSIIVIISVWEIV-GQAEGG--------LSVLRTFRLLRVLKLVRFLPALRRQLVVLMKTMDNVATFCMLLMLFIFIFSILGMHLFGCKFGLRQDSGDTLP-----DRKNFDSLLWATVTVFQILTQEDWNAVLYNGM 873 HSP 8 Score: 69.3218 bits (168), Expect = 4.919e-11 Identity = 67/297 (22.56%), Postives = 148/297 (49.83%), Query Frame = 1 Query: 2191 FQRGILIAILINTLSMGIEYHQ-QPVQLTQT-LEFSNIVFSILFLIEMILKLI------GEGILGYIKNGFNLFDGIIVVLGVIELCQQGGTSG-------LSILRTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKFCTIEN-------NKRTC---------DRKNFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTS----------SWAALYFIALMTFGNYVLFNLLVAILVEGFSSERLDEQKLLHNYRQSLKKRRANNKQLRIMQ 2958 F +L+ I +N +++ +E P + + L SN +F+++F+ EM++K++ GEG+ Y+++ +N+ DG++V + ++++ +SG L +LR R LR L+++ P L+ + +I ++ + + F +F ILG+ LF KF E N+ C + NFD+L +++++F + ++ W +++Y+G+ W L+FI+ + ++ + N+ V ++VE F R +++ R+ +++R ++ R ++ Sbjct: 1151 FDHIVLLFIFLNCITIALERPDISPRSMERVFLSVSNYIFTVIFVGEMMIKVVAMGLYFGEGV--YLQSSWNILDGVLVFVSLVDILVSIASSGGNRILGILRVLRLLRTLRPLRVISRAPGLKLVVETLITSLRPIGNIVLICCAFFIVFGILGVQLFKGKFFHCEGLHVRNITNRTECLQAGHRWVRRKYNFDNLGQALMSLFVLSCKDGWVSIMYDGLDAVGVDQQPIRNNNPWMLLFFISFLLIVSFFVLNMFVGVVVENFHKCRQQQEEEEARIREEKRQKRLEKRRRRALE 1445 HSP 9 Score: 67.781 bits (164), Expect = 1.419e-10 Identity = 36/117 (30.77%), Postives = 65/117 (55.56%), Query Frame = 1 Query: 337 FHIFHQNKHPRDWCLKIITWPWFEQLSMTIIAVNCITLSMYQPCGDQNCETSKCQIMQAFDYIIFAFFTCEMVIKIIAMG-FLGDLGYFGDTWNRLDMFIVIVGSIEILPSTGNNIG 684 ++F + R WCL++I F+ + + I +NCIT+++ +P D + + + + +YI F EM+IK++AMG + G+ Y +WN LD +V V ++IL S ++ G Sbjct: 1129 LYLFAPDNRFRLWCLRVIGHKMFDHIVLLFIFLNCITIALERP--DISPRSMERVFLSVSNYIFTVIFVGEMMIKVVAMGLYFGEGVYLQSSWNILDGVLVFVSLVDILVSIASSGG 1243 HSP 10 Score: 60.8474 bits (146), Expect = 2.145e-8 Identity = 36/124 (29.03%), Postives = 74/124 (59.68%), Query Frame = 1 Query: 2191 FQRGILIAILINTLSMGIEYHQQPVQLTQTL--EFSNIVFSILFLIEMILKLIGEGILG---YIKNGFNLFDGIIVVLGVIELCQQGGTSGLSILRTFRLLRILKLVRFMPALRQQLFVMIRTI 2547 F+R ++AIL+N +++G+ QP T ++ + +F+ F EM++K++ G++G Y+ + +N D IV++G++E G LS +RT R+LR L+ + +P++R + +++ T+ Sbjct: 90 FERVSILAILLNCVTLGMF---QPCGHTPSVLQALDDGIFA-FFAGEMVVKMVALGVIGQKGYLGDTWNRLDFFIVIVGMLEYSLDGHNVSLSAIRTVRVLRPLRAINRVPSMRILVTLLLDTL 209 HSP 11 Score: 54.6842 bits (130), Expect = 1.508e-6 Identity = 30/96 (31.25%), Postives = 52/96 (54.17%), Query Frame = 1 Query: 4426 NDCLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFHKCQENQ 4713 N C N K NFDN+G A +A+F + + +GWV IMY +DA H+ + IYFI +++ +FF++N+ + V+ F + ++ + Sbjct: 326 NQCRAGELNPHKG-AINFDNIGYAWIAIFQVITLEGWVDIMYYVMDA----------HSFYNFIYFIFLIIVGSFFMINLCLVVIATQFSETKQRE 410
BLAST of Voltage-dependent T-type calcium channel subunit alpha vs. Ensembl Medaka
Match: cacna1ha (voltage-dependent T-type calcium channel subunit alpha-1H [Source:NCBI gene;Acc:101161560]) HSP 1 Score: 577.015 bits (1486), Expect = 2.220e-171 Identity = 385/669 (57.55%), Postives = 477/669 (71.30%), Query Frame = 1 Query: 3670 EKALEEPDDSN--SESQNSSRMNNVEDPDE-EDMEAMICLSKCCPQP--KGIFAKRYYH-SLYVFSVDNQFRQKCQHIVDKKSFDYLVLFFITLNCITLAMERPSIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKFYYCDGPHLQAVKTKNDCLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFHKCQENQXXXXX--------XXXXXXXXXXXXXXXXHLRAPLYWENYSKWRRTINSVVTSKYFDLAIAGVIGLNVITMATEFHMMPQVLKTALKVFNYFFTSTFVXXXXXXXXXXXXXRYISDKWNQLDMMIVILSIAGVVIDEVE-SNFMPINPTIMRVMRVLRIARVLKLLKMASGIRALLDTVIQALPQVGNXXXXXXXXXXXXXXXXVELFGRL-ECSDINPCVGLGRHAHFENFGMAFLTLFRIATGDNWNGIMKDTLREKCISSEDCQ---RNC-CVSAIIAPIYFVIFXXXXXXXXXXXXXXXXXKHLEESHKMM 5616 +K+LE+P S+ E + + M PDE D + I L + K + K + SLY+F ++ FR CQ ++ K FD++VLFFI LNCIT+AMERP I PHS ERLFL+ +NYIFT+IF EM IKV++ G G Q YL+ WNI+DG LVF+SLLD+ ++I N+I G+LRV RLLRTLRPLRVISRAPGLKLVV+TL++SLRPIGNIVLICCTFFI+FGILGVQLFKGKFY C+G + V K+DCL+ + W N+KYNFDNL +ALM+LFVLS KDGWV IMY G+DAVGV+ QP NHN W LIYFISFLL+V+FFVLNMFVGVVVENFHKC+++QE+EE KR + ++ P Y+ +YS R I+ + T+ Y DL I ++G+N++TM+ E + Q LK ALK NY FT F +EALLKLVA G+ R+ DKWNQLD+ IV LSI G+V++E+ +PINPTI+R+MRVLRIAR L +M I + QVGNLGLLF LLF+I+AALGVELFG+L EC+DINPC GL RHA FENFGMAFLTLFR++TGDNW+GIMKDTLRE CQ RNC A ++P YFV FVL+AQFVLVNVVVAVLMKHLEES+K++ Sbjct: 955 QKSLEQPQVSSMVGEHSDCNGMTLTCSPDENADAKDDISLEDDFDEDNLKPRWCKEHEDCSLYLFDPESWFRSCCQRVISHKLFDHVVLFFIFLNCITIAMERPDIKPHSLERLFLSASNYIFTVIFLIEMAIKVVALGFCFGKQCYLQCSWNILDGLLVFVSLLDVLVSIAYVGENKILGVLRVLRLLRTLRPLRVISRAPGLKLVVETLITSLRPIGNIVLICCTFFIVFGILGVQLFKGKFYICEGFDTRNVTNKSDCLQ-ANYRWTNRKYNFDNLFKALMSLFVLSCKDGWVNIMYDGLDAVGVDQQPVRNHNPWMLIYFISFLLIVSFFVLNMFVGVVVENFHKCRQDQEEEEARLREDKRQKMIDKKRRSKENGGAGAMQRP-YYADYSPVRLYIHRLCTNHYLDLFITLIVGINILTMSVEHYNQQQYLKEALKDCNYVFTFIFFVEALLKLVAFGIHRFFKDKWNQLDVAIVALSILGIVLEELNMKGALPINPTIIRIMRVLRIARGNFLDRMELNIASFCF-------QVGNLGLLFMLLFFIYAALGVELFGKLIECTDINPCEGLSRHATFENFGMAFLTLFRVSTGDNWSGIMKDTLRE-------CQPDDRNCFAYLAWVSPFYFVTFVLIAQFVLVNVVVAVLMKHLEESNKVL 1607 HSP 2 Score: 348.977 bits (894), Expect = 1.689e-96 Identity = 220/467 (47.11%), Postives = 295/467 (63.17%), Query Frame = 1 Query: 289 INPNESLIYHGFYATVFHIFHQNKHPRDWCLKIITWP----------WFEQLSMTIIAVNCITLSMYQPCGDQNCETSKCQIMQAFDYIIFAFFTCEMVIKIIAMGFLGDLGYFGDTWNRLDMFIVIVGSIEILPSTGNNIGLTAIRTIRVLRPLRAINRIPSMRIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQMWQGVLRNRCYLNLNESFRHPGLNLSSFYQINRTLFLNAVDKDFICSTDKNNGILKCSDIPPSIMLLSNNSLQICKQPARPFTDNLPTKH--SCVNWNQYYTDCQPGEKNPYEGAINFDNIGFAWVAIFQVISMESWVDIMYYVQDAHSFWDWIYFVALIIIGSFFMINLCLVVIASQFSETKRRETERMWIERRRFNSSNCSSISKDEPQTCYLEXXXXXXXXXXXXYRRIVKLYNQIQIRHSKTAQGNY----QNKLKRQRK-HCNV 1638 I+ E + F Q PR WC++I+ P W +SM +I +NC+TL M+QPC D +C + +C+++Q D IFAFF EMVIK++A G G Y D WN+LD IV+ G +E G N L+AIRT+RVLRPLRAINR+PSMRILV LLLDTLPMLGNVL LCFFVFFIFGI+GVQ+W G+LRNRC+L + P Y ++ D FICST + NG+L C D+PPS + + ++ +L H CVNWNQYY C GE NP++GA+NFDNIG+A +AIFQVI++E WVDIMY+V DAHSF+++IYF+ LII+GSFFMINLCLVVIA+QFSETK+RE M +R R+ SS+ + S EP +CY EI++ I+ + K+ RR+ ++Y + HS + N +++ R+ HC++ Sbjct: 54 ISCEEEQPFPALAPKAFFCLKQTTRPRYWCIRIVCNPYPFTTLEKYLWRVYISMMVILLNCVTLGMFQPCEDVDCLSERCKVLQVLDDCIFAFFAVEMVIKMMAFGVFGSKCYLADRWNQLDFVIVMAGMLE-YSLDGQNASLSAIRTVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLFLCFFVFFIFGIVGVQLWAGLLRNRCFLGEDTKSLKP-------YYVDE----EGEDNPFICSTPRENGMLHCYDVPPS----TEDGVEC----------SLTASHVNGCVNWNQYYNVCHAGEFNPHKGAVNFDNIGYASIAIFQVITLEGWVDIMYFVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQRENALMREQRARYMSSDSTFSSYTEPGSCYEEILRYISHLYRKLRRRLQRIYYRW---HSGPGAAFWLRPIHNLMQQHRQEHCHL 491 HSP 3 Score: 310.071 bits (793), Expect = 1.883e-84 Identity = 176/314 (56.05%), Postives = 217/314 (69.11%), Query Frame = 1 Query: 2155 QQKIKTLVNDVKFQRGILIAILINTLSMGIEYHQQPVQLTQTLEFSNIVFSILFLIEMILKLIGEGILGYIKNGFNLFDGIIVVLGVIELCQQGGTSGLSILRTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKF-CTIENNKRTCDRKNFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTSSWAALYFIALMTFGNYVLFNLLVAILVEGFSSERLDEQKLLHNYRQSLKKRRANNKQLRIMQHQSENLVLLTNSIQKDQTGENQKISSQPPVIIHTAATPMPTPRSS 3093 ++ ++T+V F + I+ AILINT SMGIEYH+QP LTQ LE +N VF+ +F++EM L+ G+ GYIKN +N+FD ++V++ V E+ Q GLS+LRTFRLLR+LKLVRFMPALR+QL V+++T+DNVATF LL+LFIF FSILGM LFGCKF +EN DRKNFDSLLW+IVTVFQILTQEDWN VLYNGM TS WAALYF+ALMTFGNYVLFNLLVAILVEGF +E R + + L + N D G ++ PP+I+ TAATPMPTP SS Sbjct: 574 RETLRTIVESKYFNQAIMTAILINTFSMGIEYHEQPEYLTQVLEITNFVFTSIFVLEMGFMLLAFGLWGYIKNPYNIFDSVVVIISVWEISAQA-DGGLSVLRTFRLLRVLKLVRFMPALRRQLVVLMKTMDNVATFCMLLMLFIFTFSILGMHLFGCKFGLRLENGDTIPDRKNFDSLLWAIVTVFQILTQEDWNVVLYNGMASTSPWAALYFVALMTFGNYVLFNLLVAILVEGFQAE-----------------VRMTHIFFSHFFFAFKALEMTANG-HIDACG-----TTAPPIIMRTAATPMPTPTSS 863 HSP 4 Score: 105.531 bits (262), Expect = 5.243e-22 Identity = 77/292 (26.37%), Postives = 141/292 (48.29%), Query Frame = 1 Query: 3832 SLYVFSVDNQ----FRQKCQHIVDKKSFDYLVLFFITLNCITLAMERPSIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKFYYCDGPHLQAVKTKNDCLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFH 4695 S +VFS FR+ + IV+ K F+ ++ I +N ++ +E P + + L +TN++FT IF EM +L+ GL Y+K+ +NI D +V IS+ + + ++ +LR FRLLR L+ +R + P L+ + L+ ++ + ++ F F ILG+ LF KF G L+ T D + NFD+L A++ +F + +++ W ++Y G+ + + WA +YF++ + + + N+ V ++VE F Sbjct: 559 SKFVFSKAGHAWKNFRETLRTIVESKYFNQAIMTAILINTFSMGIEYHEQPEYLTQ--VLEITNFVFTSIFVLEMGFMLLAFGLW----GYIKNPYNIFDSVVVIISVWE-----ISAQADGGLSVLRTFRLLRVLKLVRFM---PALRRQLVVLMKTMDNVATFCMLLMLFIFTFSILGMHLFGCKF----GLRLENGDTIPD------------RKNFDSLLWAIVTVFQILTQEDWNVVLYNGMAST----------SPWAALYFVALMTFGNYVLFNLLVAILVEGFQ 810 HSP 5 Score: 93.2041 bits (230), Expect = 3.295e-18 Identity = 93/326 (28.53%), Postives = 152/326 (46.63%), Query Frame = 1 Query: 3907 YLVLFFITLNCITLAMERP--SIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKG---------------KFYY-----------CDGP------HLQAVKTK--------------NDCLKYSQ-------NEWKNQK--YNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFHKCQENQ 4713 Y+ + I LNC+TL M +P + S+ L V + F EM+IK+++ G+ G + YL WN +D +V +L+ + G + + I R +R LRPLR I+R P ++++V LL +L +GN++ +C F IFGI+GVQL+ G K YY C P H V N C+ ++Q E+ K NFDN+G A +A+F + + +GWV IMY +DA H+ + IYFI +++ +FF++N+ + V+ F + ++ + Sbjct: 104 YISMMVILLNCVTLGMFQPCEDVDCLSERCKVLQVLDDCIFAFFAVEMVIKMMAFGVF-GSKCYLADRWNQLDFVIVMAGMLEYSLD---GQNASLSAI----RTVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLFLCFFVFFIFGIVGVQLWAGLLRNRCFLGEDTKSLKPYYVDEEGEDNPFICSTPRENGMLHCYDVPPSTEDGVECSLTASHVNGCVNWNQYYNVCHAGEFNPHKGAVNFDNIGYASIAIFQVITLEGWVDIMYFVMDA----------HSFYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQRE 411 HSP 6 Score: 86.6557 bits (213), Expect = 2.576e-16 Identity = 71/228 (31.14%), Postives = 119/228 (52.19%), Query Frame = 1 Query: 4783 RAPLYWENYSKWRRTINSVVTSKYFDLAIAGVIGLNVITMATEFHMMPQVLKTALKVFNYFFTSTFVXXXXXXXXXXXXXRYISDKWNQLDMMIVILSIAGVVIDEVESNFMPINPTIMRVMRVLRIARVLKLLKMASGIRALLDTVIQALPQVGNXXXXXXXXXXXXXXXXVELFG-----RLECSDINPCVGLGRHAHFENFGMAFLTLFRIATGDNWNGIMKDTL 5451 +A W+N+ R T+ ++V SKYF+ AI I +N +M E+H P+ L L++ N+ FTS FVLE L+A GL YI + +N D ++VI+S+ + + V+R R+ RVLKL++ +R L +++ + V +L L + F+ LG+ LFG RLE D P +F++ A +T+F+I T ++WN ++ + + Sbjct: 565 KAGHAWKNF---RETLRTIVESKYFNQAIMTAILINTFSMGIEYHEQPEYLTQVLEITNFVFTSIFVLEMGFMLLAFGLWGYIKNPYNIFDSVVVIISVWEISAQADGG---------LSVLRTFRLLRVLKLVRFMPALRRQLVVLMKTMDNVATFCMLLMLFIFTFSILGMHLFGCKFGLRLENGDTIP-----DRKNFDSLLWAIVTVFQILTQEDWNVVLYNGM 775 HSP 7 Score: 73.1738 bits (178), Expect = 3.646e-12 Identity = 80/309 (25.89%), Postives = 149/309 (48.22%), Query Frame = 1 Query: 2140 YLSICQQKIKTLVNDVKFQRGILIAILINTLSMGIEYHQ-QPVQLTQT-LEFSNIVFSILFLIEMILKLIGEGIL----GYIKNGFNLFDGIIVVLGVIELCQQGGTSG-------LSILRTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKFCTIEN-------NKRTC--------DRK-NFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTS----------SWAALYFIALMTFGNYVLFNLLVAILVEGFSSERLD----EQKLLHNYRQSL--KKRRA 2931 + S CQ+ I + F +L I +N +++ +E +P L + L SN +F+++FLIEM +K++ G Y++ +N+ DG++V + ++++ G L +LR R LR L+++ P L+ + +I ++ + + F +F ILG+ LF KF E NK C +RK NFD+L +++++F + ++ W ++Y+G+ W +YFI+ + ++ + N+ V ++VE F R D E +L + RQ + KKRR+ Sbjct: 1025 FRSCCQRVISHKL----FDHVVLFFIFLNCITIAMERPDIKPHSLERLFLSASNYIFTVIFLIEMAIKVVALGFCFGKQCYLQCSWNILDGLLVFVSLLDVLVSIAYVGENKILGVLRVLRLLRTLRPLRVISRAPGLKLVVETLITSLRPIGNIVLICCTFFIVFGILGVQLFKGKFYICEGFDTRNVTNKSDCLQANYRWTNRKYNFDNLFKALMSLFVLSCKDGWVNIMYDGLDAVGVDQQPVRNHNPWMLIYFISFLLIVSFFVLNMFVGVVVENFHKCRQDQEEEEARLREDKRQKMIDKKRRS 1329 HSP 8 Score: 59.6918 bits (143), Expect = 4.240e-8 Identity = 57/221 (25.79%), Postives = 106/221 (47.96%), Query Frame = 1 Query: 2203 ILIAILINTLSMGIEYHQQPVQLTQTLEFSNIVFSILFLIEMILKLIGEGILGYIKNGFNLFDGIIVVLGVI-----ELCQQGGTS-GLSILRTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKF-CTIENNKRTCDR-KNFDSLLWSIVTVFQILTQEDWNTVLYNGMTRT-----SSWAALYFIALMTFGNYVL 2826 I + + IN L+M +E++ Q L + L+ N VF+ +F +E +LKL+ GI + K+ +N D IV L ++ EL +G +I+R R+LRI + F+ + + + N+ F LL G+ LFG CT N R F++ + +T+F++ T ++W+ ++ + + + +A L +++ F +VL Sbjct: 1366 ITLIVGINILTMSVEHYNQQQYLKEALKDCNYVFTFIFFVEALLKLVAFGIHRFFKDKWNQLDVAIVALSILGIVLEELNMKGALPINPTIIRIMRVLRIAR-GNFLDRMELNIASFCFQVGNLGLLFMLLFFIYAAL---GVELFGKLIECTDINPCEGLSRHATFENFGMAFLTLFRVSTGDNWSGIMKDTLRECQPDDRNCFAYLAWVSPFYFVTFVL 1582 HSP 9 Score: 57.7658 bits (138), Expect = 1.816e-7 Identity = 34/111 (30.63%), Postives = 58/111 (52.25%), Query Frame = 1 Query: 337 FHIFHQNKHPRDWCLKIITWPWFEQLSMTIIAVNCITLSMYQPCGDQNCETSKCQIMQAFDYIIFAFFTCEMVIKIIAMGF-LGDLGYFGDTWNRLDMFIVIVGSIEILPS 666 ++F R C ++I+ F+ + + I +NCIT++M +P D + + + A +YI F EM IK++A+GF G Y +WN LD +V V +++L S Sbjct: 1016 LYLFDPESWFRSCCQRVISHKLFDHVVLFFIFLNCITIAMERP--DIKPHSLERLFLSASNYIFTVIFLIEMAIKVVALGFCFGKQCYLQCSWNILDGLLVFVSLLDVLVS 1124 HSP 10 Score: 52.7582 bits (125), Expect = 5.756e-6 Identity = 39/146 (26.71%), Postives = 69/146 (47.26%), Query Frame = 1 Query: 1099 TDNLPTKHSCVNWNQYYTDCQPGEKNPYEGAINFDNIGFAWVAIFQVISMESWVDIMYYVQDA----------HSFWDWIYFVALIIIGSFFMINLCLVVIASQF---------SETKRRETERM-WIERRRFNSSNCSSISKDEP 1476 T N+ K C+ N +T+ + NFDN+ A +++F + + WV+IMY DA H+ W IYF++ ++I SFF++N+ + V+ F E + RE +R I+++R + N + + P Sbjct: 1206 TRNVTNKSDCLQANYRWTNRK----------YNFDNLFKALMSLFVLSCKDGWVNIMYDGLDAVGVDQQPVRNHNPWMLIYFISFLLIVSFFVLNMFVGVVVENFHKCRQDQEEEEARLREDKRQKMIDKKRRSKENGGAGAMQRP 1341 HSP 11 Score: 51.9878 bits (123), Expect = 9.777e-6 Identity = 23/78 (29.49%), Postives = 44/78 (56.41%), Query Frame = 1 Query: 2674 NFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTSSWAALYFIALMTFGNYVLFNLLVAILVEGFSSERLDEQKLLHNYR 2907 NFD++ ++ + +FQ++T E W ++Y M S + +YFI L+ G++ + NL + ++ FS + E L+ R Sbjct: 342 NFDNIGYASIAIFQVITLEGWVDIMYFVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQRENALMREQR 419
BLAST of Voltage-dependent T-type calcium channel subunit alpha vs. Ensembl Medaka
Match: ENSORLT00000045672.1 (pep primary_assembly:ASM223467v1:1:25452484:25669127:1 gene:ENSORLG00000026938.1 transcript:ENSORLT00000045672.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 285.419 bits (729), Expect = 3.833e-85 Identity = 178/356 (50.00%), Postives = 230/356 (64.61%), Query Frame = 1 Query: 268 QETDGTPINPNESLIYHGFYATVFHIFHQNKHPRDWCLKIITWPW-FEQLSMTIIAVNCITLSMYQPCGDQNCETSKCQIMQAFDYIIFAFFTCEMVIKIIAMGFLGDLGYFGDTWNRLDMFIVIVGSIEILPSTGNNIGLTAIRTIRVLRPLRAINRIPSMRIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQMWQGVLRNRCYLNLNESFRHPGLNLSSFYQINRTLFLNAVDKDFICSTDKNNGILKCSDIPPSIMLLSNNSLQICKQPARPFTDNLPTKHSCVNWNQYYTDCQPGEKNPYEGAINFDNIGFAWVAIFQVISMESWVDIMYYVQDAHSFWDWIYFVALIII 1332 +E DG+ L Y VF Q PR WC+ ++ P+ M +I +NC+TL MYQPC + +C + +CQ +QAFD I+ FF EM+IK++A+G G Y GDTWNRLD FIV+ G +E N+ LTAIRT+RVLRPL+AINR+PSMRILV LLLDTLPMLGNVLLLCFFVFFIFGIIGVQ+W G+LRNRCY N + L+L +Y + ++ FICS +NGI+ C D+P ++C D + CVNWNQYYT C G +NP++ AINFDNI +AW+ IFQVI++E WV+IMYYV DAHSF+++IYF+ LII+ Sbjct: 31 REEDGSSDTSVLMLPYPELVPVVFFCLKQTTFPRSWCIHMVCSPYPLNCDGMMVILLNCVTLGMYQPCENIDCSSERCQTLQAFDAFIYIFFALEMIIKMVALGIFGRRSYLGDTWNRLDFFIVMAGMVEYSLDL-QNMNLTAIRTVRVLRPLKAINRVPSMRILVNLLLDTLPMLGNVLLLCFFVFFIFGIIGVQLWAGLLRNRCYPEENFTL----LDLEEYYMPDED-----DERPFICSLPIDNGIMSCMDVPAR-----REGGRVCCLDK---DDVVSLAGLCVNWNQYYTRCHTGSRNPHKDAINFDNIAYAWIVIFQVITLEGWVEIMYYVMDAHSFYNFIYFILLIIV 368 HSP 2 Score: 75.485 bits (184), Expect = 1.851e-13 Identity = 61/174 (35.06%), Postives = 97/174 (55.75%), Query Frame = 1 Query: 3865 RQKCQHIV-DKKSFDYLVLFFITLNCITLAMERP--SIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKG 4377 R C H+V + + I LNC+TL M +P +I S+ L + I F EMIIK+++ G+ G ++YL WN +D F+V +++ ++ L + N L R +R LRPL+ I+R P ++++V LL +L +GN++L+C F IFGI+GVQL+ G Sbjct: 64 RSWCIHMVCSPYPLNCDGMMVILLNCVTLGMYQPCENIDCSSERCQTLQAFDAFIYIFFALEMIIKMVALGIF-GRRSYLGDTWNRLDFFIVMAGMVEY--SLDLQNMN-----LTAIRTVRVLRPLKAINRVPSMRILVNLLLDTLPMLGNVLLLCFFVFFIFGIIGVQLWAG 229 HSP 3 Score: 55.4546 bits (132), Expect = 4.050e-7 Identity = 34/121 (28.10%), Postives = 68/121 (56.20%), Query Frame = 1 Query: 2206 LIAILINTLSMGIEYHQQPVQLT----QTLEFSNIVFSILFLIEMILKLIGEGILG---YIKNGFNLFDGIIVVLGVIELCQQGGTSGLSILRTFRLLRILKLVRFMPALRQQLFVMIRTI 2547 ++ IL+N +++G+ + + + QTL+ + I F +EMI+K++ GI G Y+ + +N D IV+ G++E L+ +RT R+LR LK + +P++R + +++ T+ Sbjct: 82 MMVILLNCVTLGMYQPCENIDCSSERCQTLQAFDAFIYIFFALEMIIKMVALGIFGRRSYLGDTWNRLDFFIVMAGMVEYSLDLQNMNLTAIRTVRVLRPLKAINRVPSMRILVNLLLDTL 202
BLAST of Voltage-dependent T-type calcium channel subunit alpha vs. Planmine SMEST
Match: SMESG000005760.1 (SMESG000005760.1) HSP 1 Score: 3513.39 bits (9109), Expect = 0.000e+0 Identity = 1891/1897 (99.68%), Postives = 1894/1897 (99.84%), Query Frame = 1 Query: 418 MTIIAVNCITLSMYQPCGDQNCETSKCQIMQAFDYIIFAFFTCEMVIKIIAMGFLGDLGYFGDTWNRLDMFIVIVGSIEILPSTGNNIGLTAIRTIRVLRPLRAINRIPSMRIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQMWQGVLRNRCYLNLNESFRHPGLNLSSFYQINRTLFLNAVDKDFICSTDKNNGILKCSDIPPSIMLLSNNSLQICKQPARPFTDNLPTKHSCVNWNQYYTDCQPGEKNPYEGAINFDNIGFAWVAIFQVISMESWVDIMYYVQDAHSFWDWIYFVALIIIGSFFMINLCLVVIASQFSETKRRETERMWIERRRFNSSNCSSISKDEPQTCYLEXXXXXXXXXXXXYRRIVKLYNQIQIRHSKTAQGNYQNKLKRQRKHCNVCLNSRSQFPIDDHCHLYSIVNTISGDKQHYYAINKYPINFSNIPPKASPELSVIDVLNSPRHPNHLISDISSKSVSTETKRKSQYNSQILLEIPSTPANHSTTRDNYRWELTNNPLLTSKDKVYPQSVASRSSSINSCAYQIPRLTDSYSKHRRPFNKNQNKTKRKNYLSICQQKIKTLVNDVKFQRGILIAILINTLSMGIEYHQQPVQLTQTLEFSNIVFSILFLIEMILKLIGEGILGYIKNGFNLFDGIIVVLGVIELCQQGGTSGLSILRTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKFCTIENNKRTCDRKNFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTSSWAALYFIALMTFGNYVLFNLLVAILVEGFSSERLDEQKLLHNYRQSLKKRRANNKQLRIMQHQSENLVLLTNSIQKDQTGENQKISSQPPVIIHTAATPMPTPRSSPYNELVXXXXXXXXXXXXXXXQSILSINKSFETTSSRNINTTILQEDASIMPGMKNSKQNLDSTLFVEHHIPVQKTPTSNGLNVKLVSIPIPYTTNRSNFIIPSSILLRQGSINSFMGSVNSDRSKILLDEKKSISETDEKSLSRQSSFKSFMAYKNKINQLTIPFSNRYSLSLDSEGKSNYQFKMNYLLAREKALEEPDDSNSESQNSSRMNNVEDPDEEDMEAMICLSKCCPQPKGIFAKRYYHSLYVFSVDNQFRQKCQHIVDKKSFDYLVLFFITLNCITLAMERPSIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKFYYCDGPHLQAVKTKNDCLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFHKCQENQXXXXXXXXXXXXXXXXXXXXXHLRAPLYWENYSKWRRTINSVVTSKYFDLAIAGVIGLNVITMATEFHMMPQVLKTALKVFNYFFTSTFVXXXXXXXXXXXXXRYISDKWNQLDMMIVILSIAGVVIDEVESNFMPINPTIMRVMRVLRIARVLKLLKMASGIRALLDTVIQALPQVGNXXXXXXXXXXXXXXXXVELFGRLECSDINPCVGLGRHAHFENFGMAFLTLFRIATGDNWNGIMKDTLREKCISSEDCQRNCCVSAIIAPIYFVIFXXXXXXXXXXXXXXXXXKHLEESHKMMCDDYELEREVQRDLDEEAKELAREKQLKDEENNENTLIDIEIDKNNNFLDKKENNSINQNQIKKLSCGDCHSINAQLRNVSCQNVHLVNIYSKNLSRSHPHLFVNLDSASFXXXXXXXXXXXXXQRRLSMKKESWNNESVMFNNNKPMKISENPKSLKSKINKS 6108 MTIIAVNCITLSMYQPCGDQNCETSKCQIMQAFDYIIFAFFTCEMVIKIIAMGFLGDLGYFGDTWNRLDMFIVIVGSIEILPSTGNNIGLTAIRTIRVLRPLRAINRIPSMRILVMLLLDTLPMLGNVLLLCFFVFFIFGIIGVQMWQGVLRNRCYLNLNESFRHPGLNLSSFYQINRTLFLNAVDKDFICSTDKNNGILKCSDIPPSIMLLSNNSLQICKQPARPFTDNLPTKHSCVNWNQYYTDCQPGEKNPYEGAINFDNIGFAWVAIFQVISMESWVDIMYYVQDAHSFWDWIYFVALIIIGSFFMINLCLVVIASQFSETKRRETERMWIERRRFNSSNCSSISKDEPQTCYLEIIKLITQIICKIYRRIVKLYNQ+QIRHSKTAQGNYQNKLKRQRKHCNVCLNSRSQFPIDDHCHLYSIVNTISGDKQHYYAINKYPINFSNIPPKASPELSVIDVLNSPRHPNHLISDISSKSVSTETKRKSQYNSQILLEIPSTPANHSTTRDNYRWELTNNPLLTSKDKVYPQSVASRSSSINSCAYQIPRLTDS SKHR+PFNKNQNKTKRKNYLSICQQKIKTLVNDVKFQRGILIAILINTLSMGIEYHQQPVQLTQTLEFSNIVFSILFLIEMILKLIGEGILGYIKNGFNLFDGIIVVLGVIELCQQGGTSGLSILRTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATFFALLILFIFIFSILGMSLFGCKFCTIENNKRTCDRKNFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTSSWAALYFIALMTFGNYVLFNLLVAILVEGFSSERLDEQKLLHNYRQSLKKRRANNKQLRIMQHQSENLVLLTNSIQKDQTGENQKISSQPPVIIHTAATPMPTPRSSPYNELVTTPHTTFPHTNTSNSQSILSINKSFETTSSRNINTTILQEDASIMP MKNSKQNLDSTLFVEHHIPVQKTPTSNGLNVKLVSIPIPYTTNRSNFIIPSSILLRQGSINSFMGSVNSDRSKILLDEKKSISETDEKSLSRQSSFKSFMAYKNKINQLTIPFSNRYSLSLDSEGKSNYQFKMNYLLAREKALEEPDD+NSESQNSSRMNNVEDPDEEDMEAMICLSKCCPQPKGIFAKRYYHSLYVFSVDNQFRQKCQHIVDKKSFDYLVLFFITLNCITLAMERPSIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKFYYCDGPHLQAVKTKNDCLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFHKCQENQEKEEKARRAAKRARRLEKKRKHLRAPLYWENYSKWRRTINSVVTSKYFDLAIAGVIGLNVITMATEFHMMPQVLKTALKVFNYFFTSTFVLEALLKLVALGLARYISDKWNQLDMMIVILSIAGVVIDEVESNFMPINPTIMRVMRVLRIARVLKLLKMASGIRALLDTVIQALPQVGNLGLLFFLLFYIFAALGVELFGRLECSDINPCVGLGRHAHFENFGMAFLTLFRIATGDNWNGIMKDTLREKCISSEDCQRNCCVSAIIAPIYFVIFVLMAQFVLVNVVVAVLMKHLEESHKMMCDDYELEREVQRDLDEEAKELAREKQLKDEENNENTLIDIEIDKNNNFLDKKENNSINQNQIKKLSCGDCHSINAQLRNVSCQNVHLVNIYSKNLSRSHPHLFVNLDSASFTNNTKTTNLNKLLQRRLSMKKESWNNESVMFNNNKPMKISENPKSLKSKIN S Sbjct: 1 MTIIAVNCITLSMYQPCGDQNCETSKCQIMQAFDYIIFAFFTCEMVIKIIAMGFLGDLGYFGDTWNRLDMFIVIVGSIEILPSTGNNIGLTAIRTIRVLRPLRAINRIPSMRILVMLLLDTLPMLGNVLLLCFFVFFIFGIIGVQMWQGVLRNRCYLNLNESFRHPGLNLSSFYQINRTLFLNAVDKDFICSTDKNNGILKCSDIPPSIMLLSNNSLQICKQPARPFTDNLPTKHSCVNWNQYYTDCQPGEKNPYEGAINFDNIGFAWVAIFQVISMESWVDIMYYVQDAHSFWDWIYFVALIIIGSFFMINLCLVVIASQFSETKRRETERMWIERRRFNSSNCSSISKDEPQTCYLEIIKLITQIICKIYRRIVKLYNQMQIRHSKTAQGNYQNKLKRQRKHCNVCLNSRSQFPIDDHCHLYSIVNTISGDKQHYYAINKYPINFSNIPPKASPELSVIDVLNSPRHPNHLISDISSKSVSTETKRKSQYNSQILLEIPSTPANHSTTRDNYRWELTNNPLLTSKDKVYPQSVASRSSSINSCAYQIPRLTDSSSKHRKPFNKNQNKTKRKNYLSICQQKIKTLVNDVKFQRGILIAILINTLSMGIEYHQQPVQLTQTLEFSNIVFSILFLIEMILKLIGEGILGYIKNGFNLFDGIIVVLGVIELCQQGGTSGLSILRTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATFFALLILFIFIFSILGMSLFGCKFCTIENNKRTCDRKNFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTSSWAALYFIALMTFGNYVLFNLLVAILVEGFSSERLDEQKLLHNYRQSLKKRRANNKQLRIMQHQSENLVLLTNSIQKDQTGENQKISSQPPVIIHTAATPMPTPRSSPYNELVTTPHTTFPHTNTSNSQSILSINKSFETTSSRNINTTILQEDASIMPRMKNSKQNLDSTLFVEHHIPVQKTPTSNGLNVKLVSIPIPYTTNRSNFIIPSSILLRQGSINSFMGSVNSDRSKILLDEKKSISETDEKSLSRQSSFKSFMAYKNKINQLTIPFSNRYSLSLDSEGKSNYQFKMNYLLAREKALEEPDDTNSESQNSSRMNNVEDPDEEDMEAMICLSKCCPQPKGIFAKRYYHSLYVFSVDNQFRQKCQHIVDKKSFDYLVLFFITLNCITLAMERPSIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKFYYCDGPHLQAVKTKNDCLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFHKCQENQEKEEKARRAAKRARRLEKKRKHLRAPLYWENYSKWRRTINSVVTSKYFDLAIAGVIGLNVITMATEFHMMPQVLKTALKVFNYFFTSTFVLEALLKLVALGLARYISDKWNQLDMMIVILSIAGVVIDEVESNFMPINPTIMRVMRVLRIARVLKLLKMASGIRALLDTVIQALPQVGNLGLLFFLLFYIFAALGVELFGRLECSDINPCVGLGRHAHFENFGMAFLTLFRIATGDNWNGIMKDTLREKCISSEDCQRNCCVSAIIAPIYFVIFVLMAQFVLVNVVVAVLMKHLEESHKMMCDDYELEREVQRDLDEEAKELAREKQLKDEENNENTLIDIEIDKNNNFLDKKENNSINQNQIKKLSCGDCHSINAQLRNVSCQNVHLVNIYSKNLSRSHPHLFVNLDSASFTNNTKTTNLNKLLQRRLSMKKESWNNESVMFNNNKPMKISENPKSLKSKINVS 1897 HSP 2 Score: 61.6178 bits (148), Expect = 8.196e-9 Identity = 51/196 (26.02%), Postives = 85/196 (43.37%), Query Frame = 1 Query: 79 RKKYSLDSFPSSVF-YEANEFLEIENEIECLDILPQDNRSRRETLIGNKSDFNLTDKSKADHCQQETDGTPINPNESLIYHGFYATVFHIFHQNKHPRDWCLKIITWPWFEQLSMTIIAVNCITLSMYQPCGDQNCETSKCQIMQAFDYIIFAFFTCEMVIKIIAMGFL-GDLGYFGDTWNRLDMFIVIVGSIEIL 660 R SLDS S + ++ N L E +E P D S + N S N + + + + P I+ Y ++F + R C I+ F+ L + I +NCITL+M +P + + + + +YI FT EM+IK+++ G L GD Y WN +D F+V + +++ Sbjct: 1061 RYSLSLDSEGKSNYQFKMNYLLAREKALE----EPDDTNSESQ----NSSRMNNVEDPDEEDMEAMICLSKCCPQPKGIFAKRYYHSLYVFSVDNQFRQKCQHIVDKKSFDYLVLFFITLNCITLAMERPSIPPH--SKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLF 1246
BLAST of Voltage-dependent T-type calcium channel subunit alpha vs. Planmine SMEST
Match: SMESG000005760.1 (SMESG000005760.1) HSP 1 Score: 3492.21 bits (9054), Expect = 0.000e+0 Identity = 1882/1902 (98.95%), Postives = 1890/1902 (99.37%), Query Frame = 1 Query: 454 MYQPCGDQNCETSKCQIMQAFDYIIFAFFTCEMVIKIIAMGFLGDLGYFGDTWNRLDMFIVIVGSIEILPSTGNNIGLTAIRTIRVLRPLRAINRIPSMRIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQMWQGVLRNRCYLNLNESFRHPGLNLSSFYQINRTLFLNAVDKDFICSTDKNNGILKCSDIPPSIMLLSNNSLQICKQPARPFTDNLPTKHSCVNWNQYYTDCQPGEKNPYEGAINFDNIGFAWVAIFQVISMESWVDIMYYVQDAHSFWDWIYFVALIIIGSFFMINLCLVVIASQFSETKRRETERMWIERRRFNSSNCSSISKDEPQTCYLEXXXXXXXXXXXXYRRIVKLYNQIQIRHSKTAQGNYQNKLKRQRKHCNVCLNSRSQFPIDDHCHLYSIVNTISGDKQHYYAINKYPINFSNIPPKASPELSVIDVLNSPRHPNHLISDISSKSVSTETKRKSQYNSQILLEIPSTPANHSTTRDNYRWELTNNPLLTSKDKVYPQSVASRSSSINSCAYQIPRLTDSYSKHRRPFNKNQNKTKRKNYLSICQQKIKTLVNDVKFQRGILIAILINTLSMGIEYHQQPVQLTQTLEFSNIVFSILFLIEMILKLIGEGILGYIKNGFNLFDGIIVVLGVIELCQQGGTSGLSILRTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKFCTIENNKRTCDRKNFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTSSWAALYFIALMTFGNYVLFNLLVAILVEGFSSERLDEQKLLHNYRQSLKKRRANNKQLRIMQHQSENLVLLTNSIQKDQTGENQKISSQPPVIIHTAATPMPTPRSSPYNELVXXXXXXXXXXXXXXXQSILSINKSFETTSSRNINTTILQEDASIMPGMKNSKQNLDSTLFVEHHIPVQKTPTSNGLNVKLVSIPIPYTTNRSNFIIPSSILLRQGSINSFMGSVNSDRSKILLDEKKSISETDEKSLSRQSSFKSFMAYKNKINQLTIPFSNRYSLSLDSEGKSNYQFKMNYLLAREKALEEPDDSNSESQNSSRMNNVEDPDEEDMEAMICLSKCCPQPKGIFAKRYYHSLYVFSVDNQFRQKCQHIVDKKSFDYLVLFFITLNCITLAMERPSIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKFYYCDGPHLQAVKTKNDCLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFHKCQENQXXXXXXXXXXXXXXXXXXXXXHLRAPLYWENYSKWRRTINSVVTSKYFDLAIAGVIGLNVITMATEFHMMPQVLKTALKVFNYFFTSTFVXXXXXXXXXXXXXRYISDKWNQLDMMIVILSIAGVVIDEVESNFMPINPTIMRVMRVLRIARVLKLLKMASGIRALLDTVIQALPQVGNXXXXXXXXXXXXXXXXVELFGRLECSDINPCVGLGRHAHFENFGMAFLTLFRIATGDNWNGIMKDTLREKCISSEDCQRNCCVSAIIAPIYFVIFXXXXXXXXXXXXXXXXXKHLEESHKMMCDDYELEREVQRDLDEEAKELAREKQLKDEENNENTLIDIEIDKNNNFLDKKENNSINQNQIKKLSCGDCHSINAQLRNVSCQNVHLVNIYSKNLSRSHPHLFVNLDSASFXXXXXXXXXXXXXQRRLSMKKESWNNESVMFNNNKPMKISENPKSLKSKINKSQQSTTEL---RLSEKRK 6150 MYQPCGDQNCETSKCQIMQAFDYIIFAFFTCEMVIKIIAMGFLGDLGYFGDTWNRLDMFIVIVGSIEILPSTGNNIGLTAIRTIRVLRPLRAINRIPSMRILVMLLLDTLPMLGNVLLLCFFVFFIFGIIGVQMWQGVLRNRCYLNLNESFRHPGLNLSSFYQINRTLFLNAVDKDFICSTDKNNGILKCSDIPPSIMLLSNNSLQICKQPARPFTDNLPTKHSCVNWNQYYTDCQPGEKNPYEGAINFDNIGFAWVAIFQVISMESWVDIMYYVQDAHSFWDWIYFVALIIIGSFFMINLCLVVIASQFSETKRRETERMWIERRRFNSSNCSSISKDEPQTCYLEIIKLITQIICKIYRRIVKLYNQ+QIRHSKTAQGNYQNKLKRQRKHCNVCLNSRSQFPIDDHCHLYSIVNTISGDKQHYYAINKYPINFSNIPPKASPELSVIDVLNSPRHPNHLISDISSKSVSTETKRKSQYNSQILLEIPSTPANHSTTRDNYRWELTNNPLLTSKDKVYPQSVASRSSSINSCAYQIPRLTDS SKHR+PFNKNQNKTKRKNYLSICQQKIKTLVNDVKFQRGILIAILINTLSMGIEYHQQPVQLTQTLEFSNIVFSILFLIEMILKLIGEGILGYIKNGFNLFDGIIVVLGVIELCQQGGTSGLSILRTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATFFALLILFIFIFSILGMSLFGCKFCTIENNKRTCDRKNFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTSSWAALYFIALMTFGNYVLFNLLVAILVEGFSSERLDEQKLLHNYRQSLKKRRANNKQLRIMQHQSENLVLLTNSIQKDQTGENQKISSQPPVIIHTAATPMPTPRSSPYNELVTTPHTTFPHTNTSNSQSILSINKSFETTSSRNINTTILQEDASIMP MKNSKQNLDSTLFVEHHIPVQKTPTSNGLNVKLVSIPIPYTTNRSNFIIPSSILLRQGSINSFMGSVNSDRSKILLDEKKSISETDEKSLSRQSSFKSFMAYKNKINQLTIPFSNRYSLSLDSEGKSNYQFKMNYLLAREKALEEPDD+NSESQNSSRMNNVEDPDEEDMEAMICLSKCCPQPKGIFAKRYYHSLYVFSVDNQFRQKCQHIVDKKSFDYLVLFFITLNCITLAMERPSIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKFYYCDGPHLQAVKTKNDCLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFHKCQENQEKEEKARRAAKRARRLEKKRKHLRAPLYWENYSKWRRTINSVVTSKYFDLAIAGVIGLNVITMATEFHMMPQVLKTALKVFNYFFTSTFVLEALLKLVALGLARYISDKWNQLDMMIVILSIAGVVIDEVESNFMPINPTIMRVMRVLRIARVLKLLKMASGIRALLDTVIQALPQVGNLGLLFFLLFYIFAALGVELFGRLECSDINPCVGLGRHAHFENFGMAFLTLFRIATGDNWNGIMKDTLREKCISSEDCQRNCCVSAIIAPIYFVIFVLMAQFVLVNVVVAVLMKHLEESHKMMCDDYELEREVQRDLDEEAKELAREKQLKDEENNENTLIDIEIDKNNNFLDKKENNSINQNQIKKLSCGDCHSINAQLRNVSCQNVHLVNIYSKNLSRSHPHLFVNLDSASFTNNTKTTNLNKLLQRRLSMKKESWNNESVMFNNNKPMKISENPKSLKSKIN + + L ++ +KRK Sbjct: 1 MYQPCGDQNCETSKCQIMQAFDYIIFAFFTCEMVIKIIAMGFLGDLGYFGDTWNRLDMFIVIVGSIEILPSTGNNIGLTAIRTIRVLRPLRAINRIPSMRILVMLLLDTLPMLGNVLLLCFFVFFIFGIIGVQMWQGVLRNRCYLNLNESFRHPGLNLSSFYQINRTLFLNAVDKDFICSTDKNNGILKCSDIPPSIMLLSNNSLQICKQPARPFTDNLPTKHSCVNWNQYYTDCQPGEKNPYEGAINFDNIGFAWVAIFQVISMESWVDIMYYVQDAHSFWDWIYFVALIIIGSFFMINLCLVVIASQFSETKRRETERMWIERRRFNSSNCSSISKDEPQTCYLEIIKLITQIICKIYRRIVKLYNQMQIRHSKTAQGNYQNKLKRQRKHCNVCLNSRSQFPIDDHCHLYSIVNTISGDKQHYYAINKYPINFSNIPPKASPELSVIDVLNSPRHPNHLISDISSKSVSTETKRKSQYNSQILLEIPSTPANHSTTRDNYRWELTNNPLLTSKDKVYPQSVASRSSSINSCAYQIPRLTDSSSKHRKPFNKNQNKTKRKNYLSICQQKIKTLVNDVKFQRGILIAILINTLSMGIEYHQQPVQLTQTLEFSNIVFSILFLIEMILKLIGEGILGYIKNGFNLFDGIIVVLGVIELCQQGGTSGLSILRTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATFFALLILFIFIFSILGMSLFGCKFCTIENNKRTCDRKNFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTSSWAALYFIALMTFGNYVLFNLLVAILVEGFSSERLDEQKLLHNYRQSLKKRRANNKQLRIMQHQSENLVLLTNSIQKDQTGENQKISSQPPVIIHTAATPMPTPRSSPYNELVTTPHTTFPHTNTSNSQSILSINKSFETTSSRNINTTILQEDASIMPRMKNSKQNLDSTLFVEHHIPVQKTPTSNGLNVKLVSIPIPYTTNRSNFIIPSSILLRQGSINSFMGSVNSDRSKILLDEKKSISETDEKSLSRQSSFKSFMAYKNKINQLTIPFSNRYSLSLDSEGKSNYQFKMNYLLAREKALEEPDDTNSESQNSSRMNNVEDPDEEDMEAMICLSKCCPQPKGIFAKRYYHSLYVFSVDNQFRQKCQHIVDKKSFDYLVLFFITLNCITLAMERPSIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKFYYCDGPHLQAVKTKNDCLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFHKCQENQEKEEKARRAAKRARRLEKKRKHLRAPLYWENYSKWRRTINSVVTSKYFDLAIAGVIGLNVITMATEFHMMPQVLKTALKVFNYFFTSTFVLEALLKLVALGLARYISDKWNQLDMMIVILSIAGVVIDEVESNFMPINPTIMRVMRVLRIARVLKLLKMASGIRALLDTVIQALPQVGNLGLLFFLLFYIFAALGVELFGRLECSDINPCVGLGRHAHFENFGMAFLTLFRIATGDNWNGIMKDTLREKCISSEDCQRNCCVSAIIAPIYFVIFVLMAQFVLVNVVVAVLMKHLEESHKMMCDDYELEREVQRDLDEEAKELAREKQLKDEENNENTLIDIEIDKNNNFLDKKENNSINQNQIKKLSCGDCHSINAQLRNVSCQNVHLVNIYSKNLSRSHPHLFVNLDSASFTNNTKTTNLNKLLQRRLSMKKESWNNESVMFNNNKPMKISENPKSLKSKINSTLNACWRLLLPQMVQKRK 1902 HSP 2 Score: 61.6178 bits (148), Expect = 8.228e-9 Identity = 51/196 (26.02%), Postives = 85/196 (43.37%), Query Frame = 1 Query: 79 RKKYSLDSFPSSVF-YEANEFLEIENEIECLDILPQDNRSRRETLIGNKSDFNLTDKSKADHCQQETDGTPINPNESLIYHGFYATVFHIFHQNKHPRDWCLKIITWPWFEQLSMTIIAVNCITLSMYQPCGDQNCETSKCQIMQAFDYIIFAFFTCEMVIKIIAMGFL-GDLGYFGDTWNRLDMFIVIVGSIEIL 660 R SLDS S + ++ N L E +E P D S + N S N + + + + P I+ Y ++F + R C I+ F+ L + I +NCITL+M +P + + + + +YI FT EM+IK+++ G L GD Y WN +D F+V + +++ Sbjct: 1049 RYSLSLDSEGKSNYQFKMNYLLAREKALE----EPDDTNSESQ----NSSRMNNVEDPDEEDMEAMICLSKCCPQPKGIFAKRYYHSLYVFSVDNQFRQKCQHIVDKKSFDYLVLFFITLNCITLAMERPSIPPH--SKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLF 1234
BLAST of Voltage-dependent T-type calcium channel subunit alpha vs. Planmine SMEST
Match: SMESG000005760.1 (SMESG000005760.1) HSP 1 Score: 3490.66 bits (9050), Expect = 0.000e+0 Identity = 1879/1885 (99.68%), Postives = 1882/1885 (99.84%), Query Frame = 1 Query: 454 MYQPCGDQNCETSKCQIMQAFDYIIFAFFTCEMVIKIIAMGFLGDLGYFGDTWNRLDMFIVIVGSIEILPSTGNNIGLTAIRTIRVLRPLRAINRIPSMRIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQMWQGVLRNRCYLNLNESFRHPGLNLSSFYQINRTLFLNAVDKDFICSTDKNNGILKCSDIPPSIMLLSNNSLQICKQPARPFTDNLPTKHSCVNWNQYYTDCQPGEKNPYEGAINFDNIGFAWVAIFQVISMESWVDIMYYVQDAHSFWDWIYFVALIIIGSFFMINLCLVVIASQFSETKRRETERMWIERRRFNSSNCSSISKDEPQTCYLEXXXXXXXXXXXXYRRIVKLYNQIQIRHSKTAQGNYQNKLKRQRKHCNVCLNSRSQFPIDDHCHLYSIVNTISGDKQHYYAINKYPINFSNIPPKASPELSVIDVLNSPRHPNHLISDISSKSVSTETKRKSQYNSQILLEIPSTPANHSTTRDNYRWELTNNPLLTSKDKVYPQSVASRSSSINSCAYQIPRLTDSYSKHRRPFNKNQNKTKRKNYLSICQQKIKTLVNDVKFQRGILIAILINTLSMGIEYHQQPVQLTQTLEFSNIVFSILFLIEMILKLIGEGILGYIKNGFNLFDGIIVVLGVIELCQQGGTSGLSILRTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKFCTIENNKRTCDRKNFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTSSWAALYFIALMTFGNYVLFNLLVAILVEGFSSERLDEQKLLHNYRQSLKKRRANNKQLRIMQHQSENLVLLTNSIQKDQTGENQKISSQPPVIIHTAATPMPTPRSSPYNELVXXXXXXXXXXXXXXXQSILSINKSFETTSSRNINTTILQEDASIMPGMKNSKQNLDSTLFVEHHIPVQKTPTSNGLNVKLVSIPIPYTTNRSNFIIPSSILLRQGSINSFMGSVNSDRSKILLDEKKSISETDEKSLSRQSSFKSFMAYKNKINQLTIPFSNRYSLSLDSEGKSNYQFKMNYLLAREKALEEPDDSNSESQNSSRMNNVEDPDEEDMEAMICLSKCCPQPKGIFAKRYYHSLYVFSVDNQFRQKCQHIVDKKSFDYLVLFFITLNCITLAMERPSIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKFYYCDGPHLQAVKTKNDCLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFHKCQENQXXXXXXXXXXXXXXXXXXXXXHLRAPLYWENYSKWRRTINSVVTSKYFDLAIAGVIGLNVITMATEFHMMPQVLKTALKVFNYFFTSTFVXXXXXXXXXXXXXRYISDKWNQLDMMIVILSIAGVVIDEVESNFMPINPTIMRVMRVLRIARVLKLLKMASGIRALLDTVIQALPQVGNXXXXXXXXXXXXXXXXVELFGRLECSDINPCVGLGRHAHFENFGMAFLTLFRIATGDNWNGIMKDTLREKCISSEDCQRNCCVSAIIAPIYFVIFXXXXXXXXXXXXXXXXXKHLEESHKMMCDDYELEREVQRDLDEEAKELAREKQLKDEENNENTLIDIEIDKNNNFLDKKENNSINQNQIKKLSCGDCHSINAQLRNVSCQNVHLVNIYSKNLSRSHPHLFVNLDSASFXXXXXXXXXXXXXQRRLSMKKESWNNESVMFNNNKPMKISENPKSLKSKINKS 6108 MYQPCGDQNCETSKCQIMQAFDYIIFAFFTCEMVIKIIAMGFLGDLGYFGDTWNRLDMFIVIVGSIEILPSTGNNIGLTAIRTIRVLRPLRAINRIPSMRILVMLLLDTLPMLGNVLLLCFFVFFIFGIIGVQMWQGVLRNRCYLNLNESFRHPGLNLSSFYQINRTLFLNAVDKDFICSTDKNNGILKCSDIPPSIMLLSNNSLQICKQPARPFTDNLPTKHSCVNWNQYYTDCQPGEKNPYEGAINFDNIGFAWVAIFQVISMESWVDIMYYVQDAHSFWDWIYFVALIIIGSFFMINLCLVVIASQFSETKRRETERMWIERRRFNSSNCSSISKDEPQTCYLEIIKLITQIICKIYRRIVKLYNQ+QIRHSKTAQGNYQNKLKRQRKHCNVCLNSRSQFPIDDHCHLYSIVNTISGDKQHYYAINKYPINFSNIPPKASPELSVIDVLNSPRHPNHLISDISSKSVSTETKRKSQYNSQILLEIPSTPANHSTTRDNYRWELTNNPLLTSKDKVYPQSVASRSSSINSCAYQIPRLTDS SKHR+PFNKNQNKTKRKNYLSICQQKIKTLVNDVKFQRGILIAILINTLSMGIEYHQQPVQLTQTLEFSNIVFSILFLIEMILKLIGEGILGYIKNGFNLFDGIIVVLGVIELCQQGGTSGLSILRTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATFFALLILFIFIFSILGMSLFGCKFCTIENNKRTCDRKNFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTSSWAALYFIALMTFGNYVLFNLLVAILVEGFSSERLDEQKLLHNYRQSLKKRRANNKQLRIMQHQSENLVLLTNSIQKDQTGENQKISSQPPVIIHTAATPMPTPRSSPYNELVTTPHTTFPHTNTSNSQSILSINKSFETTSSRNINTTILQEDASIMP MKNSKQNLDSTLFVEHHIPVQKTPTSNGLNVKLVSIPIPYTTNRSNFIIPSSILLRQGSINSFMGSVNSDRSKILLDEKKSISETDEKSLSRQSSFKSFMAYKNKINQLTIPFSNRYSLSLDSEGKSNYQFKMNYLLAREKALEEPDD+NSESQNSSRMNNVEDPDEEDMEAMICLSKCCPQPKGIFAKRYYHSLYVFSVDNQFRQKCQHIVDKKSFDYLVLFFITLNCITLAMERPSIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKFYYCDGPHLQAVKTKNDCLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFHKCQENQEKEEKARRAAKRARRLEKKRKHLRAPLYWENYSKWRRTINSVVTSKYFDLAIAGVIGLNVITMATEFHMMPQVLKTALKVFNYFFTSTFVLEALLKLVALGLARYISDKWNQLDMMIVILSIAGVVIDEVESNFMPINPTIMRVMRVLRIARVLKLLKMASGIRALLDTVIQALPQVGNLGLLFFLLFYIFAALGVELFGRLECSDINPCVGLGRHAHFENFGMAFLTLFRIATGDNWNGIMKDTLREKCISSEDCQRNCCVSAIIAPIYFVIFVLMAQFVLVNVVVAVLMKHLEESHKMMCDDYELEREVQRDLDEEAKELAREKQLKDEENNENTLIDIEIDKNNNFLDKKENNSINQNQIKKLSCGDCHSINAQLRNVSCQNVHLVNIYSKNLSRSHPHLFVNLDSASFTNNTKTTNLNKLLQRRLSMKKESWNNESVMFNNNKPMKISENPKSLKSKIN S Sbjct: 1 MYQPCGDQNCETSKCQIMQAFDYIIFAFFTCEMVIKIIAMGFLGDLGYFGDTWNRLDMFIVIVGSIEILPSTGNNIGLTAIRTIRVLRPLRAINRIPSMRILVMLLLDTLPMLGNVLLLCFFVFFIFGIIGVQMWQGVLRNRCYLNLNESFRHPGLNLSSFYQINRTLFLNAVDKDFICSTDKNNGILKCSDIPPSIMLLSNNSLQICKQPARPFTDNLPTKHSCVNWNQYYTDCQPGEKNPYEGAINFDNIGFAWVAIFQVISMESWVDIMYYVQDAHSFWDWIYFVALIIIGSFFMINLCLVVIASQFSETKRRETERMWIERRRFNSSNCSSISKDEPQTCYLEIIKLITQIICKIYRRIVKLYNQMQIRHSKTAQGNYQNKLKRQRKHCNVCLNSRSQFPIDDHCHLYSIVNTISGDKQHYYAINKYPINFSNIPPKASPELSVIDVLNSPRHPNHLISDISSKSVSTETKRKSQYNSQILLEIPSTPANHSTTRDNYRWELTNNPLLTSKDKVYPQSVASRSSSINSCAYQIPRLTDSSSKHRKPFNKNQNKTKRKNYLSICQQKIKTLVNDVKFQRGILIAILINTLSMGIEYHQQPVQLTQTLEFSNIVFSILFLIEMILKLIGEGILGYIKNGFNLFDGIIVVLGVIELCQQGGTSGLSILRTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATFFALLILFIFIFSILGMSLFGCKFCTIENNKRTCDRKNFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTSSWAALYFIALMTFGNYVLFNLLVAILVEGFSSERLDEQKLLHNYRQSLKKRRANNKQLRIMQHQSENLVLLTNSIQKDQTGENQKISSQPPVIIHTAATPMPTPRSSPYNELVTTPHTTFPHTNTSNSQSILSINKSFETTSSRNINTTILQEDASIMPRMKNSKQNLDSTLFVEHHIPVQKTPTSNGLNVKLVSIPIPYTTNRSNFIIPSSILLRQGSINSFMGSVNSDRSKILLDEKKSISETDEKSLSRQSSFKSFMAYKNKINQLTIPFSNRYSLSLDSEGKSNYQFKMNYLLAREKALEEPDDTNSESQNSSRMNNVEDPDEEDMEAMICLSKCCPQPKGIFAKRYYHSLYVFSVDNQFRQKCQHIVDKKSFDYLVLFFITLNCITLAMERPSIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKFYYCDGPHLQAVKTKNDCLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFHKCQENQEKEEKARRAAKRARRLEKKRKHLRAPLYWENYSKWRRTINSVVTSKYFDLAIAGVIGLNVITMATEFHMMPQVLKTALKVFNYFFTSTFVLEALLKLVALGLARYISDKWNQLDMMIVILSIAGVVIDEVESNFMPINPTIMRVMRVLRIARVLKLLKMASGIRALLDTVIQALPQVGNLGLLFFLLFYIFAALGVELFGRLECSDINPCVGLGRHAHFENFGMAFLTLFRIATGDNWNGIMKDTLREKCISSEDCQRNCCVSAIIAPIYFVIFVLMAQFVLVNVVVAVLMKHLEESHKMMCDDYELEREVQRDLDEEAKELAREKQLKDEENNENTLIDIEIDKNNNFLDKKENNSINQNQIKKLSCGDCHSINAQLRNVSCQNVHLVNIYSKNLSRSHPHLFVNLDSASFTNNTKTTNLNKLLQRRLSMKKESWNNESVMFNNNKPMKISENPKSLKSKINVS 1885 HSP 2 Score: 62.003 bits (149), Expect = 7.098e-9 Identity = 51/196 (26.02%), Postives = 85/196 (43.37%), Query Frame = 1 Query: 79 RKKYSLDSFPSSVF-YEANEFLEIENEIECLDILPQDNRSRRETLIGNKSDFNLTDKSKADHCQQETDGTPINPNESLIYHGFYATVFHIFHQNKHPRDWCLKIITWPWFEQLSMTIIAVNCITLSMYQPCGDQNCETSKCQIMQAFDYIIFAFFTCEMVIKIIAMGFL-GDLGYFGDTWNRLDMFIVIVGSIEIL 660 R SLDS S + ++ N L E +E P D S + N S N + + + + P I+ Y ++F + R C I+ F+ L + I +NCITL+M +P + + + + +YI FT EM+IK+++ G L GD Y WN +D F+V + +++ Sbjct: 1049 RYSLSLDSEGKSNYQFKMNYLLAREKALE----EPDDTNSESQ----NSSRMNNVEDPDEEDMEAMICLSKCCPQPKGIFAKRYYHSLYVFSVDNQFRQKCQHIVDKKSFDYLVLFFITLNCITLAMERPSIPPH--SKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLF 1234
BLAST of Voltage-dependent T-type calcium channel subunit alpha vs. Planmine SMEST
Match: SMESG000000986.1 (SMESG000000986.1) HSP 1 Score: 878.241 bits (2268), Expect = 0.000e+0 Identity = 514/766 (67.10%), Postives = 606/766 (79.11%), Query Frame = 1 Query: 3712 QNSSRMNNVEDPDEEDMEAMICLSKCCPQPKGIFAKRYYHSLYVFSVDNQFRQKCQHIVDKKSFDYLVLFFITLNCITLAMERPSIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKFYYCDGPHLQAVKTKNDCLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFHKCQENQXXXXXXXXXXXXXXXXXXXXXHLRAPLYWENYSKWRRTINSVVTSKYFDLAIAGVIGLNVITMATEFHMMPQVLKTALKVFNYFFTSTFVXXXXXXXXXXXXXRYISDKWNQLDMMIVILSIAGVVIDEVESNFMPINPTIMRVMRVLRIARVLKLLKMASGIRALLDTVIQALPQVGNXXXXXXXXXXXXXXXXVELFGRLECSDINPCVGLGRHAHFENFGMAFLTLFRIATGDNWNGIMKDTLREKCISSEDCQRNCCVSAIIAPIYFVIFXXXXXXXXXXXXXXXXXKHLEESHKMMCDDYELEREVQRDLDEEAKELARE---KQLKDEENNENTLIDIEI--DKNNNFLDKKENNSINQNQIKKLSC----------GDCHSINAQLRNVSCQNVHLVNIYS-----KNLSRSHPHLFVNLDSASF 5949 ++SS +N +D E+ E ++C C F YY SL+V S DN+FR CQ++++KK FD +VLFFI LNCITLAMERPSIP S+ER FLT+TNY+FT+IF EM IKV++KGLL+G +YL+SGWN+MDG LV ISL D+ I +++GHS++IFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGI GVQLFKGKFYYC GP + VK ++C +N WKNQ+YNFDNLGQALM+LFVLSSKDGWVQIMYTG+DAVGVN QPQEN+NEW L+YFISFLLLV FFVLNMFVGVVVENFHKC+ENQEKEEKARRAAKRARRLEKK+K + P YW+ Y WR I+ +V SKYFDLAIAG+IGLNVITMA EF+MMP L+ ALK NY FTS F++EAL+K +A G RYI D+WNQLD++IVILS++G+V++E+++ ++PIN TI+RV RVLRIARVLKLLKMA GIRALLDTVIQALPQVGNLGLLFFLLF+IFAALGVELFGRLECSD NPC GL RHAHFENFGMAFLTLFRIATGDNWNGIMKDTLR KC +SE+CQ+NCCVS IIAPIYFVIFVLMAQFVLVNVVVAVLMKHLEESHKMMCDD E+E+EVQR++DEE KE RE +++ EN N I +I NNN + + + I N++ + S N S +H++N+ + + LS+S P L VNL+ S Sbjct: 1192 EDSSLLNQDQDDHNENEEKILCNYFWCSWLSKFFRAHYYDSLFVLSPDNRFRNSCQNLMEKKVFDNIVLFFIALNCITLAMERPSIPQKSREREFLTITNYVFTVIFAVEMTIKVIAKGLLVGKHSYLRSGWNVMDGLLVVISLADIMIVLIIGHSSKIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGIFGVQLFKGKFYYCSGPDVAHVKNFSECNNDKRNTWKNQQYNFDNLGQALMSLFVLSSKDGWVQIMYTGLDAVGVNQQPQENYNEWYLLYFISFLLLVGFFVLNMFVGVVVENFHKCRENQEKEEKARRAAKRARRLEKKKKKMMQPPYWKFYPHWRLLIHGLVNSKYFDLAIAGIIGLNVITMAMEFYMMPVELEVALKSLNYIFTSVFIIEALIKTIAYGPKRYIIDRWNQLDVLIVILSVSGIVMEEMKNKYIPINMTIIRVFRVLRIARVLKLLKMAKGIRALLDTVIQALPQVGNLGLLFFLLFFIFAALGVELFGRLECSDYNPCTGLSRHAHFENFGMAFLTLFRIATGDNWNGIMKDTLRNKCDNSEECQKNCCVSPIIAPIYFVIFVLMAQFVLVNVVVAVLMKHLEESHKMMCDDDEIEKEVQREIDEENKEKLRENITSDVEEIENRGNKEIKEQIIEPNNNNIVYEPKKIEIKCNRLSNSAAVKFNRNANSQDSADSGKTPPDNGSGGTLHILNLPASRKLHEQLSQSQPLLLVNLNPDSL 1957 HSP 2 Score: 457.988 bits (1177), Expect = 1.671e-130 Identity = 252/374 (67.38%), Postives = 302/374 (80.75%), Query Frame = 1 Query: 454 MYQPCGDQNCETSKCQIMQAFDYIIFAFFTCEMVIKIIAMGFLGDLGYFGDTWNRLDMFIVIVGSIEILPSTGNNIGLTAIRTIRVLRPLRAINRIPSMRIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQMWQGVLRNRCYLNLNESFRHPGLNLSSFYQINRTLFLNAVDKDFICSTDKNNGILKCSDIPPSIMLLSNNSLQICKQPARPFTDNLPTKHSCVNWNQYYTDCQPGEKNPYEGAINFDNIGFAWVAIFQVISMESWVDIMYYVQDAHSFWDWIYFVALIIIGSFFMINLCLVVIASQFSETKRRETERMWIERRRFNSSNCSSISKDEPQTCYLEXXXXXXXXXXXXYRRIVKLYNQIQIRH 1575 MY+PC D +C+T +C+I+ FD+ IF FF E++IKI AMG LG GYF ++WNRLDM IVI G IE +PSTG + LTAIRT+RVLRPLRAINRIPSMRILVMLLLDTLPMLGNVLLLCFFVFFIFGI+GVQMWQG+LRNRCYL+LN S+RHPGLNLS +YQ+N+T + KDFICS D NG++KCSDIPPS++ L + ++C A P +DN+PT SCVNWNQYY+ C+ NPY GAINFDNIGFAWVAIFQVISMESWVDIMYYVQDAHSFWDW YFV+LIIIGSFFMINLCLVVIA+QFSETK+RETERM +ER++ S++ S EPQ+CY EIIKLI++ + + ++K Y + +H Sbjct: 1 MYKPCEDTSCKTIRCKILGGFDHCIFMFFAVELMIKICAMGLLGPSGYFSESWNRLDMVIVIAGLIECIPSTGE-MSLTAIRTVRVLRPLRAINRIPSMRILVMLLLDTLPMLGNVLLLCFFVFFIFGIVGVQMWQGILRNRCYLHLNSSYRHPGLNLSYYYQVNQTTTQLSPHKDFICSPDNFNGLVKCSDIPPSVIWLPSGEARVCNDSALPNSDNMPTNVSCVNWNQYYSKCEARANNPYYGAINFDNIGFAWVAIFQVISMESWVDIMYYVQDAHSFWDWSYFVSLIIIGSFFMINLCLVVIATQFSETKKRETERMLMERKKQQSTSTLG-SSIEPQSCYHEIIKLISRFCRHLLKTVIKRYERFSEKH 372 HSP 3 Score: 400.979 bits (1029), Expect = 1.506e-112 Identity = 218/331 (65.86%), Postives = 265/331 (80.06%), Query Frame = 1 Query: 2155 QQKIKTLVNDVKFQRGILIAILINTLSMGIEYHQQPVQLTQTLEFSNIVFSILFLIEMILKLIGEGILGYIKNGFNLFDGIIVVLGVIELCQQGGTSGLSILRTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKFCTIENNKRTCDRKNFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTSSWAALYFIALMTFGNYVLFNLLVAILVEGFSSERLDEQKLL-------HNYRQ--SLKKRRANNKQLRIMQHQSENLVLLTNS-----IQKDQTGENQKISSQPPVIIHTAATPMPTPRSSPYNE 3105 ++K+K++V FQRGILIAILINTLSMGIEYH QPV LT TLE+SN++F+ LFL+EM+LK++ EG+LGYI NGFN+FDG IV+LG++EL Q+GG SGLS+LRTFRLLRILKLVRFMPALR QL VM++T+DNVATFFALLILFIFIFSILGMSLFGCKFC +N KR CDRKNFDSLLW+IVTVFQILTQEDWN VL +GM++TSSWAALYF+ALMTFGNYVLFNLLVAILVEGFS+ER+DE KL HN + +L K A+ Q + E +++N+ I+K + Q + P+I HT ATPMP+PR+SP+N+ Sbjct: 622 RKKMKSIVAHRYFQRGILIAILINTLSMGIEYHNQPVLLTNTLEYSNMIFNGLFLVEMLLKILAEGLLGYISNGFNVFDGGIVILGLVELAQEGGASGLSVLRTFRLLRILKLVRFMPALRLQLIVMLKTMDNVATFFALLILFIFIFSILGMSLFGCKFCKFKNGKRKCDRKNFDSLLWAIVTVFQILTQEDWNAVLISGMSQTSSWAALYFVALMTFGNYVLFNLLVAILVEGFSTERVDEAKLAEKIHLEKHNEEKMANLMKHEAHKNQETTKKSSIEPQEVISNNKNIAIIRKGSLNQKQVM----PIITHTDATPMPSPRASPFND 948 HSP 4 Score: 112.079 bits (279), Expect = 4.210e-24 Identity = 75/281 (26.69%), Postives = 142/281 (50.53%), Query Frame = 1 Query: 3859 QFRQKCQHIVDKKSFDYLVLFFITLNCITLAMERPSIPPHSKERLF---LTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKFYYCDGPHLQAVKTKNDCLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENF 4692 +FR+K + IV + F +L I +N +++ +E H++ L L +N IF +F EM++K+L++GLL Y+ +G+N+ DG +V + L++L G ++ + +LR FRLLR L+ +R + P L+L + +L ++ + + F IF ILG+ LF KF K+ + K + NFD+L A++ +F + +++ W ++ +G+ + WA +YF++ + + + N+ V ++VE F Sbjct: 620 RFRKKMKSIVAHRYFQRGILIAILINTLSMGIEY-----HNQPVLLTNTLEYSNMIFNGLFLVEMLLKILAEGLL----GYISNGFNVFDGGIVILGLVELAQE---GGASGL-SVLRTFRLLRILKLVRFM---PALRLQLIVMLKTMDNVATFFALLILFIFIFSILGMSLFGCKF-----------------CKFKNGKRKCDRKNFDSLLWAIVTVFQILTQEDWNAVLISGMSQT----------SSWAALYFVALMTFGNYVLFNLLVAILVEGF 857 HSP 5 Score: 84.3445 bits (207), Expect = 1.045e-15 Identity = 64/208 (30.77%), Postives = 111/208 (53.37%), Query Frame = 1 Query: 2164 IKTLVNDVKFQRGILIAILINTLSMGIEYHQQPVQLTQTLEFSNIVFSILFLIEMILKLIGEGILGYIKNGFNLFDGIIVVLGVIELCQQGGTS-----GLSILRTFRLLRI---LKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKFCTIENNKRTCDR-KNFDSLLWSIVTVFQILTQEDWNTVLYNGM 2760 I LVN F I I +N ++M +E++ PV+L L+ N +F+ +F+IE ++K I G YI + +N D +IV+L V + + + ++I+R FR+LRI LKL++ +R L +I+ + V L L FIF+ LG+ LFG C+ N R +F++ + +T+F+I T ++WN ++ + + Sbjct: 1564 IHGLVNSKYFDLAIAGIIGLNVITMAMEFYMMPVELEVALKSLNYIFTSVFIIEALIKTIAYGPKRYIIDRWNQLDVLIVILSVSGIVMEEMKNKYIPINMTIIRVFRVLRIARVLKLLKMAKGIRALLDTVIQALPQVGNLGLLFFLLFFIFAALGVELFGRLECSDYNPCTGLSRHAHFENFGMAFLTLFRIATGDNWNGIMKDTL 1771 HSP 6 Score: 76.2554 bits (186), Expect = 3.204e-13 Identity = 71/269 (26.39%), Postives = 133/269 (49.44%), Query Frame = 1 Query: 2191 FQRGILIAILINTLSMGIEYHQQPVQLTQTLEF---SNIVFSILFLIEMILKLIGEGIL----GYIKNGFNLFDGIIVVLGV----IELCQQGGTSGLSILRTFRLLRILK---LVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKF--CT------------IENNKRTC---DRKNFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTS----------SWAALYFIALMTFGNYVLFNLLVAILVEGFSSER 2874 F +L I +N +++ +E P Q ++ EF +N VF+++F +EM +K+I +G+L Y+++G+N+ DG++VV+ + I L + ILR FRLLR L+ ++ P L+ + ++ ++ + + F IF I G+ LF KF C+ N+KR + NFD+L +++++F + +++ W ++Y G+ W LYFI+ + + + N+ V ++VE F R Sbjct: 1255 FDNIVLFFIALNCITLAMERPSIP-QKSREREFLTITNYVFTVIFAVEMTIKVIAKGLLVGKHSYLRSGWNVMDGLLVVISLADIMIVLIIGHSSKIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGIFGVQLFKGKFYYCSGPDVAHVKNFSECNNDKRNTWKNQQYNFDNLGQALMSLFVLSSKDGWVQIMYTGLDAVGVNQQPQENYNEWYLLYFISFLLLVGFFVLNMFVGVVVENFHKCR 1522 HSP 7 Score: 73.9442 bits (180), Expect = 1.407e-12 Identity = 64/209 (30.62%), Postives = 109/209 (52.15%), Query Frame = 1 Query: 4813 KWRRTINSVVTSKYFDLAIAGVIGLNVITMATEFHMMPQVLKTALKVFNYFFTSTFVXXXXXXXXXXXXXRYISDKWNQLDMMIVILSIAGVVIDEVESNFMPINPTIMRVMRVLRIARVLKLLKMASGIRALLDTVIQALPQVGNXXXXXXXXXXXXXXXXVELFGRLECSDINPCVGLGRHAHFENFGMAFLTLFRIATGDNWNGIM 5439 ++R+ + S+V +YF I I +N ++M E+H P +L L+ N F F++E LLK++A GL YIS+ +N D IVIL + + + S + V+R R+ R+LKL++ +R L +++ + V L L +IF+ LG+ LFG C N R +F++ A +T+F+I T ++WN ++ Sbjct: 620 RFRKKMKSIVAHRYFQRGILIAILINTLSMGIEYHNQPVLLTNTLEYSNMIFNGLFLVEMLLKILAEGLLGYISNGFNVFDGGIVILGLVELAQEGGASG--------LSVLRTFRLLRILKLVRFMPALRLQLIVMLKTMDNVATFFALLILFIFIFSILGMSLFGCKFCKFKNGKRKCDRK-NFDSLLWAIVTVFQILTQEDWNAVL 819 HSP 8 Score: 63.1586 bits (152), Expect = 2.786e-9 Identity = 43/118 (36.44%), Postives = 69/118 (58.47%), Query Frame = 1 Query: 4024 IIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKG 4377 + F E++IK+ + GLL G Y WN +D +V L++ + G + L R +R LRPLR I+R P ++++V LL +L +GN++L+C F IFGI+GVQ+++G Sbjct: 27 MFFAVELMIKICAMGLL-GPSGYFSESWNRLDMVIVIAGLIECIPST--GEMS-----LTAIRTVRVLRPLRAINRIPSMRILVMLLLDTLPMLGNVLLLCFFVFFIFGIVGVQMWQG 136 HSP 9 Score: 58.9214 bits (141), Expect = 5.646e-8 Identity = 33/114 (28.95%), Postives = 61/114 (53.51%), Query Frame = 1 Query: 322 FYATVFHIFHQNKHPRDWCLKIITWPWFEQLSMTIIAVNCITLSMYQPCGDQNCETSKCQIMQAFDYIIFAFFTCEMVIKIIAMGFL-GDLGYFGDTWNRLDMFIVIVGSIEIL 660 +Y ++F + N+ R+ C ++ F+ + + IA+NCITL+M +P Q ++ + + + +Y+ F EM IK+IA G L G Y WN +D +V++ +I+ Sbjct: 1229 YYDSLFVLSPDNRF-RNSCQNLMEKKVFDNIVLFFIALNCITLAMERPSIPQ--KSREREFLTITNYVFTVIFAVEMTIKVIAKGLLVGKHSYLRSGWNVMDGLLVVISLADIM 1339 HSP 10 Score: 54.6842 bits (130), Expect = 1.224e-6 Identity = 30/80 (37.50%), Postives = 47/80 (58.75%), Query Frame = 1 Query: 517 DYIIFAFFTCEMVIKIIAMGFLGDLGYFGDTWNRLDMFIVIVGSIEILPSTGNNIGLTAIRTIRVLRPLRAINRIPSMRI 756 + I F EM++KI+A G LG Y + +N D IVI+G +E L G GL+ +RT R+LR L+ + +P++R+ Sbjct: 668 NMIFNGLFLVEMLLKILAEGLLG---YISNGFNVFDGGIVILGLVE-LAQEGGASGLSVLRTFRLLRILKLVRFMPALRL 743 HSP 11 Score: 54.299 bits (129), Expect = 1.342e-6 Identity = 27/90 (30.00%), Postives = 53/90 (58.89%), Query Frame = 1 Query: 2287 FSNIVFSILFLIEMILKLIGEGILG---YIKNGFNLFDGIIVVLGVIELCQQGGTSGLSILRTFRLLRILKLVRFMPALRQQLFVMIRTI 2547 F + +F + F +E+++K+ G+LG Y +N D +IV+ G+IE G L+ +RT R+LR L+ + +P++R + +++ T+ Sbjct: 21 FDHCIF-MFFAVELMIKICAMGLLGPSGYFSESWNRLDMVIVIAGLIECIPSTGEMSLTAIRTVRVLRPLRAINRIPSMRILVMLLLDTL 109 HSP 12 Score: 52.7582 bits (125), Expect = 4.244e-6 Identity = 24/81 (29.63%), Postives = 46/81 (56.79%), Query Frame = 1 Query: 1195 NFDNIGFAWVAIFQVISMESWVDIMYYVQDAHSFWDWIYFVALIIIGSFFMINLCLVVIASQFSETKRRE---TERMWIER 1428 NFD++ +A V +FQ+++ E W ++ S W +YFVAL+ G++ + NL + ++ FS + E E++ +E+ Sbjct: 795 NFDSLLWAIVTVFQILTQEDWNAVLISGMSQTSSWAALYFVALMTFGNYVLFNLLVAILVEGFSTERVDEAKLAEKIHLEK 875 HSP 13 Score: 52.7582 bits (125), Expect = 4.464e-6 Identity = 26/80 (32.50%), Postives = 46/80 (57.50%), Query Frame = 1 Query: 4474 NFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFHKCQENQ 4713 NFDN+G A +A+F + S + WV IMY DA H+ W YF+S +++ +FF++N+ + V+ F + ++ + Sbjct: 247 NFDNIGFAWVAIFQVISMESWVDIMYYVQDA----------HSFWDWSYFVSLIIIGSFFMINLCLVVIATQFSETKKRE 316 HSP 14 Score: 52.373 bits (124), Expect = 5.370e-6 Identity = 25/97 (25.77%), Postives = 54/97 (55.67%), Query Frame = 1 Query: 1147 YTDCQPGEKNPYEGA-INFDNIGFAWVAIFQVISMESWVDIMYYVQDA----------HSFWDWIYFVALIIIGSFFMINLCLVVIASQFSETKRRE 1404 +++C ++N ++ NFDN+G A +++F + S + WV IMY DA ++ W +YF++ +++ FF++N+ + V+ F + + + Sbjct: 1429 FSECNNDKRNTWKNQQYNFDNLGQALMSLFVLSSKDGWVQIMYTGLDAVGVNQQPQENYNEWYLLYFISFLLLVGFFVLNMFVGVVVENFHKCRENQ 1525
BLAST of Voltage-dependent T-type calcium channel subunit alpha vs. Planmine SMEST
Match: SMESG000000986.1 (SMESG000000986.1) HSP 1 Score: 619.002 bits (1595), Expect = 0.000e+0 Identity = 336/486 (69.14%), Postives = 402/486 (82.72%), Query Frame = 1 Query: 3712 QNSSRMNNVEDPDEEDMEAMICLSKCCPQPKGIFAKRYYHSLYVFSVDNQFRQKCQHIVDKKSFDYLVLFFITLNCITLAMERPSIPPHSKERLFLTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKFYYCDGPHLQAVKTKNDCLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFHKCQENQXXXXXXXXXXXXXXXXXXXXXHLRAPLYWENYSKWRRTINSVVTSKYFDLAIAGVIGLNVITMATEFHMMPQVLKTALKVFNYFFTSTFVXXXXXXXXXXXXXRYISDKWNQLDMMIVILSIAGVVIDEVESNFMPINPTIMRVMRVLRIAR 5169 ++SS +N +D E+ E ++C C F YY SL+V S DN+FR CQ++++KK FD +VLFFI LNCITLAMERPSIP S+ER FLT+TNY+FT+IF EM IKV++KGLL+G +YL+SGWN+MDG LV ISL D+ I +++GHS++IFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGI GVQLFKGKFYYC GP + VK ++C +N WKNQ+YNFDNLGQALM+LFVLSSKDGWVQIMYTG+DAVGVN QPQEN+NEW L+YFISFLLLV FFVLNMFVGVVVENFHKC+ENQEKEEKARRAAKRARRLEKK+K + P YW+ Y WR I+ +V SKYFDLAIAG+IGLNVITMA EF+MMP L+ ALK NY FTS F++EAL+K +A G RYI D+WNQLD++IVILS++G+V++E+++ ++PIN TI+RV RVLRIAR Sbjct: 1192 EDSSLLNQDQDDHNENEEKILCNYFWCSWLSKFFRAHYYDSLFVLSPDNRFRNSCQNLMEKKVFDNIVLFFIALNCITLAMERPSIPQKSREREFLTITNYVFTVIFAVEMTIKVIAKGLLVGKHSYLRSGWNVMDGLLVVISLADIMIVLIIGHSSKIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGIFGVQLFKGKFYYCSGPDVAHVKNFSECNNDKRNTWKNQQYNFDNLGQALMSLFVLSSKDGWVQIMYTGLDAVGVNQQPQENYNEWYLLYFISFLLLVGFFVLNMFVGVVVENFHKCRENQEKEEKARRAAKRARRLEKKKKKMMQPPYWKFYPHWRLLIHGLVNSKYFDLAIAGIIGLNVITMAMEFYMMPVELEVALKSLNYIFTSVFIIEALIKTIAYGPKRYIIDRWNQLDVLIVILSVSGIVMEEMKNKYIPINMTIIRVFRVLRIAR 1677 HSP 2 Score: 456.062 bits (1172), Expect = 1.016e-131 Identity = 252/374 (67.38%), Postives = 302/374 (80.75%), Query Frame = 1 Query: 454 MYQPCGDQNCETSKCQIMQAFDYIIFAFFTCEMVIKIIAMGFLGDLGYFGDTWNRLDMFIVIVGSIEILPSTGNNIGLTAIRTIRVLRPLRAINRIPSMRIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQMWQGVLRNRCYLNLNESFRHPGLNLSSFYQINRTLFLNAVDKDFICSTDKNNGILKCSDIPPSIMLLSNNSLQICKQPARPFTDNLPTKHSCVNWNQYYTDCQPGEKNPYEGAINFDNIGFAWVAIFQVISMESWVDIMYYVQDAHSFWDWIYFVALIIIGSFFMINLCLVVIASQFSETKRRETERMWIERRRFNSSNCSSISKDEPQTCYLEXXXXXXXXXXXXYRRIVKLYNQIQIRH 1575 MY+PC D +C+T +C+I+ FD+ IF FF E++IKI AMG LG GYF ++WNRLDM IVI G IE +PSTG + LTAIRT+RVLRPLRAINRIPSMRILVMLLLDTLPMLGNVLLLCFFVFFIFGI+GVQMWQG+LRNRCYL+LN S+RHPGLNLS +YQ+N+T + KDFICS D NG++KCSDIPPS++ L + ++C A P +DN+PT SCVNWNQYY+ C+ NPY GAINFDNIGFAWVAIFQVISMESWVDIMYYVQDAHSFWDW YFV+LIIIGSFFMINLCLVVIA+QFSETK+RETERM +ER++ S++ S EPQ+CY EIIKLI++ + + ++K Y + +H Sbjct: 1 MYKPCEDTSCKTIRCKILGGFDHCIFMFFAVELMIKICAMGLLGPSGYFSESWNRLDMVIVIAGLIECIPSTGE-MSLTAIRTVRVLRPLRAINRIPSMRILVMLLLDTLPMLGNVLLLCFFVFFIFGIVGVQMWQGILRNRCYLHLNSSYRHPGLNLSYYYQVNQTTTQLSPHKDFICSPDNFNGLVKCSDIPPSVIWLPSGEARVCNDSALPNSDNMPTNVSCVNWNQYYSKCEARANNPYYGAINFDNIGFAWVAIFQVISMESWVDIMYYVQDAHSFWDWSYFVSLIIIGSFFMINLCLVVIATQFSETKKRETERMLMERKKQQSTSTLG-SSIEPQSCYHEIIKLISRFCRHLLKTVIKRYERFSEKH 372 HSP 3 Score: 399.438 bits (1025), Expect = 4.284e-113 Identity = 218/331 (65.86%), Postives = 265/331 (80.06%), Query Frame = 1 Query: 2155 QQKIKTLVNDVKFQRGILIAILINTLSMGIEYHQQPVQLTQTLEFSNIVFSILFLIEMILKLIGEGILGYIKNGFNLFDGIIVVLGVIELCQQGGTSGLSILRTFRLLRILKLVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKFCTIENNKRTCDRKNFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTSSWAALYFIALMTFGNYVLFNLLVAILVEGFSSERLDEQKLL-------HNYRQ--SLKKRRANNKQLRIMQHQSENLVLLTNS-----IQKDQTGENQKISSQPPVIIHTAATPMPTPRSSPYNE 3105 ++K+K++V FQRGILIAILINTLSMGIEYH QPV LT TLE+SN++F+ LFL+EM+LK++ EG+LGYI NGFN+FDG IV+LG++EL Q+GG SGLS+LRTFRLLRILKLVRFMPALR QL VM++T+DNVATFFALLILFIFIFSILGMSLFGCKFC +N KR CDRKNFDSLLW+IVTVFQILTQEDWN VL +GM++TSSWAALYF+ALMTFGNYVLFNLLVAILVEGFS+ER+DE KL HN + +L K A+ Q + E +++N+ I+K + Q + P+I HT ATPMP+PR+SP+N+ Sbjct: 622 RKKMKSIVAHRYFQRGILIAILINTLSMGIEYHNQPVLLTNTLEYSNMIFNGLFLVEMLLKILAEGLLGYISNGFNVFDGGIVILGLVELAQEGGASGLSVLRTFRLLRILKLVRFMPALRLQLIVMLKTMDNVATFFALLILFIFIFSILGMSLFGCKFCKFKNGKRKCDRKNFDSLLWAIVTVFQILTQEDWNAVLISGMSQTSSWAALYFVALMTFGNYVLFNLLVAILVEGFSTERVDEAKLAEKIHLEKHNEEKMANLMKHEAHKNQETTKKSSIEPQEVISNNKNIAIIRKGSLNQKQVM----PIITHTDATPMPSPRASPFND 948 HSP 4 Score: 109.383 bits (272), Expect = 2.538e-23 Identity = 75/281 (26.69%), Postives = 142/281 (50.53%), Query Frame = 1 Query: 3859 QFRQKCQHIVDKKSFDYLVLFFITLNCITLAMERPSIPPHSKERLF---LTVTNYIFTIIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGKFYYCDGPHLQAVKTKNDCLKYSQNEWKNQKYNFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENF 4692 +FR+K + IV + F +L I +N +++ +E H++ L L +N IF +F EM++K+L++GLL Y+ +G+N+ DG +V + L++L G ++ + +LR FRLLR L+ +R + P L+L + +L ++ + + F IF ILG+ LF KF K+ + K + NFD+L A++ +F + +++ W ++ +G+ + WA +YF++ + + + N+ V ++VE F Sbjct: 620 RFRKKMKSIVAHRYFQRGILIAILINTLSMGIEY-----HNQPVLLTNTLEYSNMIFNGLFLVEMLLKILAEGLL----GYISNGFNVFDGGIVILGLVELAQE---GGASGL-SVLRTFRLLRILKLVRFM---PALRLQLIVMLKTMDNVATFFALLILFIFIFSILGMSLFGCKF-----------------CKFKNGKRKCDRKNFDSLLWAIVTVFQILTQEDWNAVLISGMSQT----------SSWAALYFVALMTFGNYVLFNLLVAILVEGF 857 HSP 5 Score: 75.0998 bits (183), Expect = 7.137e-13 Identity = 88/333 (26.43%), Postives = 164/333 (49.25%), Query Frame = 1 Query: 4813 KWRRTINSVVTSKYFDLAIAGVIGLNVITMATEFHMMPQVLKTALKVFNYFFTSTFVXXXXXXXXXXXXXRYISDKWNQLDMMIVILSIAGVVIDEVESNFMPINPTIMRVMRVLRIARVLKLLKMASGIRALLDTVIQALPQVGNXXXXXXXXXXXXXXXXVELFGRLECSDINPCVGLGRHAHFENFGMAFLTLFRIATGDNWNGIMKDTLREKCISSEDCQRNCCVSAIIAPIYFVIFXXXXXXXXXXXXXXXXXKHLEESHKMMCDDYELEREV--QRDLDEEAKELAREKQLKDEENNENTLIDI-EIDKNNNFLDKKENNSINQNQI 5802 ++R+ + S+V +YF I I +N ++M E+H P +L L+ N F F++E LLK++A GL YIS+ +N D IVIL + + + S + V+R R+ R+LKL++ +R L +++ + V L L +IF+ LG+ LFG C N R +F++ A +T+F+I T ++WN ++ + + ++ A +YFV + +VL N++VA+L++ D+ +L ++ ++ +E+ L + + K++E + + I+ E+ NN + S+NQ Q+ Sbjct: 620 RFRKKMKSIVAHRYFQRGILIAILINTLSMGIEYHNQPVLLTNTLEYSNMIFNGLFLVEMLLKILAEGLLGYISNGFNVFDGGIVILGLVELAQEGGASG--------LSVLRTFRLLRILKLVRFMPALRLQLIVMLKTMDNVATFFALLILFIFIFSILGMSLFGCKFCKFKNGKRKCDR-KNFDSLLWAIVTVFQILTQEDWNAVLISGMSQ--------------TSSWAALYFVALMTFGNYVLFNLLVAILVEGFSTER---VDEAKLAEKIHLEKHNEEKMANLMKHEAHKNQETTKKSSIEPQEVISNNKNIAIIRKGSLNQKQV 926 HSP 6 Score: 75.0998 bits (183), Expect = 7.444e-13 Identity = 71/269 (26.39%), Postives = 133/269 (49.44%), Query Frame = 1 Query: 2191 FQRGILIAILINTLSMGIEYHQQPVQLTQTLEF---SNIVFSILFLIEMILKLIGEGIL----GYIKNGFNLFDGIIVVLGV----IELCQQGGTSGLSILRTFRLLRILK---LVRFMPALRQQLFVMIRTIDNVATXXXXXXXXXXXXXXXGMSLFGCKF--CT------------IENNKRTC---DRKNFDSLLWSIVTVFQILTQEDWNTVLYNGMTRTS----------SWAALYFIALMTFGNYVLFNLLVAILVEGFSSER 2874 F +L I +N +++ +E P Q ++ EF +N VF+++F +EM +K+I +G+L Y+++G+N+ DG++VV+ + I L + ILR FRLLR L+ ++ P L+ + ++ ++ + + F IF I G+ LF KF C+ N+KR + NFD+L +++++F + +++ W ++Y G+ W LYFI+ + + + N+ V ++VE F R Sbjct: 1255 FDNIVLFFIALNCITLAMERPSIP-QKSREREFLTITNYVFTVIFAVEMTIKVIAKGLLVGKHSYLRSGWNVMDGLLVVISLADIMIVLIIGHSSKIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGIFGVQLFKGKFYYCSGPDVAHVKNFSECNNDKRNTWKNQQYNFDNLGQALMSLFVLSSKDGWVQIMYTGLDAVGVNQQPQENYNEWYLLYFISFLLLVGFFVLNMFVGVVVENFHKCR 1522 HSP 7 Score: 64.3142 bits (155), Expect = 1.228e-9 Identity = 41/122 (33.61%), Postives = 67/122 (54.92%), Query Frame = 1 Query: 2164 IKTLVNDVKFQRGILIAILINTLSMGIEYHQQPVQLTQTLEFSNIVFSILFLIEMILKLIGEGILGYIKNGFNLFDGIIVVLGVIELCQQGGTS-----GLSILRTFRLLRILK--LVRFMP 2508 I LVN F I I +N ++M +E++ PV+L L+ N +F+ +F+IE ++K I G YI + +N D +IV+L V + + + ++I+R FR+LRI + RFMP Sbjct: 1564 IHGLVNSKYFDLAIAGIIGLNVITMAMEFYMMPVELEVALKSLNYIFTSVFIIEALIKTIAYGPKRYIIDRWNQLDVLIVILSVSGIVMEEMKNKYIPINMTIIRVFRVLRIARGEKFRFMP 1685 HSP 8 Score: 62.003 bits (149), Expect = 6.556e-9 Identity = 43/118 (36.44%), Postives = 69/118 (58.47%), Query Frame = 1 Query: 4024 IIFTGEMIIKVLSKGLLIGDQAYLKSGWNIMDGFLVFISLLDLFITILLGHSNRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKG 4377 + F E++IK+ + GLL G Y WN +D +V L++ + G + L R +R LRPLR I+R P ++++V LL +L +GN++L+C F IFGI+GVQ+++G Sbjct: 27 MFFAVELMIKICAMGLL-GPSGYFSESWNRLDMVIVIAGLIECIPST--GEMS-----LTAIRTVRVLRPLRAINRIPSMRILVMLLLDTLPMLGNVLLLCFFVFFIFGIVGVQMWQG 136 HSP 9 Score: 61.2326 bits (147), Expect = 9.902e-9 Identity = 68/235 (28.94%), Postives = 122/235 (51.91%), Query Frame = 1 Query: 4813 KWRRTINSVVTSKYFDLAIAGVIGLNVITMATEFHMMPQVLKTA--LKVFNYFFTSTFVXXXXXXXXX----XXXXRYISDKWNQLDMMIVILSIAGVVIDEVESNFMPINPTIMRVMRVLRIARVLKLLKMASGIRALLDTVIQALPQVGNXXXXXXXXXXXXXXXXVELF-GRL---------------ECSDINPCVGLGRHAHFENFGMAFLTLFRIATGDNWNGIMKDTL 5451 ++R + +++ K FD + I LN IT+A E +PQ + L + NY FT F +E +K++A +G Y+ WN +D ++V++S+A ++I + + I I+RV R+LR R L+++ A G++ ++ T++ +L +GN+ L+ F IF GV+LF G+ EC++ + +F+N G A ++LF +++ D W IM L Sbjct: 1241 RFRNSCQNLMEKKVFDNIVLFFIALNCITLAMERPSIPQKSREREFLTITNYVFTVIFAVEMTIKVIAKGLLVGKHSYLRSGWNVMDGLLVVISLADIMIVLIIGHSSKIF-GILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGIFGVQLFKGKFYYCSGPDVAHVKNFSECNNDKRNTWKNQQYNFDNLGQALMSLFVLSSKDGWVQIMYTGL 1474 HSP 10 Score: 56.9954 bits (136), Expect = 1.837e-7 Identity = 33/114 (28.95%), Postives = 61/114 (53.51%), Query Frame = 1 Query: 322 FYATVFHIFHQNKHPRDWCLKIITWPWFEQLSMTIIAVNCITLSMYQPCGDQNCETSKCQIMQAFDYIIFAFFTCEMVIKIIAMGFL-GDLGYFGDTWNRLDMFIVIVGSIEIL 660 +Y ++F + N+ R+ C ++ F+ + + IA+NCITL+M +P Q ++ + + + +Y+ F EM IK+IA G L G Y WN +D +V++ +I+ Sbjct: 1229 YYDSLFVLSPDNRF-RNSCQNLMEKKVFDNIVLFFIALNCITLAMERPSIPQ--KSREREFLTITNYVFTVIFAVEMTIKVIAKGLLVGKHSYLRSGWNVMDGLLVVISLADIM 1339 HSP 11 Score: 53.9138 bits (128), Expect = 1.666e-6 Identity = 30/80 (37.50%), Postives = 47/80 (58.75%), Query Frame = 1 Query: 517 DYIIFAFFTCEMVIKIIAMGFLGDLGYFGDTWNRLDMFIVIVGSIEILPSTGNNIGLTAIRTIRVLRPLRAINRIPSMRI 756 + I F EM++KI+A G LG Y + +N D IVI+G +E L G GL+ +RT R+LR L+ + +P++R+ Sbjct: 668 NMIFNGLFLVEMLLKILAEGLLG---YISNGFNVFDGGIVILGLVE-LAQEGGASGLSVLRTFRLLRILKLVRFMPALRL 743 HSP 12 Score: 53.1434 bits (126), Expect = 3.293e-6 Identity = 27/90 (30.00%), Postives = 53/90 (58.89%), Query Frame = 1 Query: 2287 FSNIVFSILFLIEMILKLIGEGILG---YIKNGFNLFDGIIVVLGVIELCQQGGTSGLSILRTFRLLRILKLVRFMPALRQQLFVMIRTI 2547 F + +F + F +E+++K+ G+LG Y +N D +IV+ G+IE G L+ +RT R+LR L+ + +P++R + +++ T+ Sbjct: 21 FDHCIF-MFFAVELMIKICAMGLLGPSGYFSESWNRLDMVIVIAGLIECIPSTGEMSLTAIRTVRVLRPLRAINRIPSMRILVMLLLDTL 109 HSP 13 Score: 51.9878 bits (123), Expect = 6.677e-6 Identity = 26/80 (32.50%), Postives = 46/80 (57.50%), Query Frame = 1 Query: 4474 NFDNLGQALMALFVLSSKDGWVQIMYTGIDAVGVNIQPQENHNEWALIYFISFLLLVAFFVLNMFVGVVVENFHKCQENQ 4713 NFDN+G A +A+F + S + WV IMY DA H+ W YF+S +++ +FF++N+ + V+ F + ++ + Sbjct: 247 NFDNIGFAWVAIFQVISMESWVDIMYYVQDA----------HSFWDWSYFVSLIIIGSFFMINLCLVVIATQFSETKKRE 316 HSP 14 Score: 51.6026 bits (122), Expect = 8.522e-6 Identity = 27/98 (27.55%), Postives = 52/98 (53.06%), Query Frame = 1 Query: 1195 NFDNIGFAWVAIFQVISMESWVDIMYYVQDAHSFWDWIYFVALIIIGSFFMINLCLVVIASQFSETKRRE---TERMWIERRRFNSSNCSSISKDEPQ 1479 NFD++ +A V +FQ+++ E W ++ S W +YFVAL+ G++ + NL + ++ FS + E E++ +E+ N +++ K E Sbjct: 795 NFDSLLWAIVTVFQILTQEDWNAVLISGMSQTSSWAALYFVALMTFGNYVLFNLLVAILVEGFSTERVDEAKLAEKIHLEKH--NEEKMANLMKHEAH 890 HSP 15 Score: 51.6026 bits (122), Expect = 9.428e-6 Identity = 25/97 (25.77%), Postives = 54/97 (55.67%), Query Frame = 1 Query: 1147 YTDCQPGEKNPYEGA-INFDNIGFAWVAIFQVISMESWVDIMYYVQDA----------HSFWDWIYFVALIIIGSFFMINLCLVVIASQFSETKRRE 1404 +++C ++N ++ NFDN+G A +++F + S + WV IMY DA ++ W +YF++ +++ FF++N+ + V+ F + + + Sbjct: 1429 FSECNNDKRNTWKNQQYNFDNLGQALMSLFVLSSKDGWVQIMYTGLDAVGVNQQPQENYNEWYLLYFISFLLLVGFFVLNMFVGVVVENFHKCRENQ 1525 The following BLAST results are available for this feature:
BLAST of Voltage-dependent T-type calcium channel subunit alpha vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Voltage-dependent T-type calcium channel subunit alpha vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Voltage-dependent T-type calcium channel subunit alpha vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Voltage-dependent T-type calcium channel subunit alpha vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Voltage-dependent T-type calcium channel subunit alpha vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Voltage-dependent T-type calcium channel subunit alpha vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Voltage-dependent T-type calcium channel subunit alpha vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Voltage-dependent T-type calcium channel subunit alpha vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Voltage-dependent T-type calcium channel subunit alpha vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Voltage-dependent T-type calcium channel subunit alpha vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Voltage-dependent T-type calcium channel subunit alpha vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 1
BLAST of Voltage-dependent T-type calcium channel subunit alpha vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Voltage-dependent T-type calcium channel subunit alpha vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Voltage-dependent T-type calcium channel subunit alpha vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30018324 ID=SMED30018324|Name=Voltage-dependent T-type calcium channel subunit alpha|organism=Schmidtea mediterranea sexual|type=transcript|length=6305bpback to top protein sequence of SMED30018324-orf-1 >SMED30018324-orf-1 ID=SMED30018324-orf-1|Name=SMED30018324-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=2050bp MKKSENKVERKKYSLDSFPSSVFYEANEFLEIENEIECLDILPQDNRSRRback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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