Iroquois-class homeodomain protein IRX-4

Overview
NameIroquois-class homeodomain protein IRX-4
Smed IDSMED30018309
Length (bp)1503
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Iroquois-class homeodomain protein IRX-4 (SMED30018309) t-SNE clustered cells

Violin plots show distribution of expression levels for Iroquois-class homeodomain protein IRX-4 (SMED30018309) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Iroquois-class homeodomain protein IRX-4 (SMED30018309) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Iroquois-class homeodomain protein IRX-4 (SMED30018309) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30018309

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 8

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
nervous systemSMED30018309h1SMcG0010817 dd_Smed_v4_11500_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30018309h1SMcG0010817 dd_Smed_v4_11500_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neuronSMED30018309h1SMcG0010817 dd_Smed_v4_11500_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		whole organism asexual adult colorimetric in situ hybridization evidence
muscle cellSMED30018309h1SMcG0010817 dd_Smed_v4_11500_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cilated neuronSMED30018309h1SMcG0010817 dd_Smed_v4_11500_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
posterior sideSMED30018309h1SMcG0010817 dd_Smed_v4_11500_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
posterior muscle cellSMED30018309h1SMcG0010817 dd_Smed_v4_11500_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
head regionSMED30018309h1SMcG0010817 dd_Smed_v6_11500_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017		whole organism asexual adult RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Iroquois-class homeodomain protein IRX-4 vs. Ensembl Human
Match: IRX2 (iroquois homeobox 2 [Source:HGNC Symbol;Acc:HGNC:14359])

HSP 1 Score: 145.206 bits (365), Expect = 1.718e-37
Identity = 78/131 (59.54%), Postives = 94/131 (71.76%), Query Frame = 2 
Query:  692 NPYGYIGNPTLDLNSARRKNATRESTSTLKAWLQEHIKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWSPKNRS-------DDATNSDQETDTKCKE----TDSDDGLKTDCQLDTLSD 1051
            +PYG    P    + A RKNATR++T+TLKAWL EH KNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTW+P+N+S        DAT S  E+  K +E    +  D+G+     +D+L+D
Sbjct:  101 HPYGSAAYPYQLNDPAYRKNATRDATATLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWAPRNKSEDEDEDEGDATRSKDESPDKAQEGTETSAEDEGI--SLHVDSLTD 229
[Close]
BLAST of Iroquois-class homeodomain protein IRX-4 vs. Ensembl Human
Match: IRX2 (iroquois homeobox 2 [Source:HGNC Symbol;Acc:HGNC:14359])

HSP 1 Score: 145.206 bits (365), Expect = 1.718e-37
Identity = 78/131 (59.54%), Postives = 94/131 (71.76%), Query Frame = 2 
Query:  692 NPYGYIGNPTLDLNSARRKNATRESTSTLKAWLQEHIKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWSPKNRS-------DDATNSDQETDTKCKE----TDSDDGLKTDCQLDTLSD 1051
            +PYG    P    + A RKNATR++T+TLKAWL EH KNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTW+P+N+S        DAT S  E+  K +E    +  D+G+     +D+L+D
Sbjct:  101 HPYGSAAYPYQLNDPAYRKNATRDATATLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWAPRNKSEDEDEDEGDATRSKDESPDKAQEGTETSAEDEGI--SLHVDSLTD 229
[Close]
BLAST of Iroquois-class homeodomain protein IRX-4 vs. Ensembl Human
Match: IRX6 (iroquois homeobox 6 [Source:HGNC Symbol;Acc:HGNC:14675])

HSP 1 Score: 144.05 bits (362), Expect = 2.304e-37
Identity = 75/132 (56.82%), Postives = 90/132 (68.18%), Query Frame = 2 
Query:  626 SAAHMMAADHNPYATYDNSAWANPYGYIGNPTLDLNSA-RRKNATRESTSTLKAWLQEHIKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWSPKNRSDDATNSD--QETDTKCKETDSDD 1012
            +A    ++   P A Y        Y Y     ++L+ A RRKNATRE+TSTLKAWL EH KNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTW+PKN+  +   ++  +E    C   D+ +
Sbjct:  110 AAGSFTSSLAQPGAYYPYERTLGQYQYERYGAVELSGAGRRKNATRETTSTLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWAPKNKGGEERKAEGGEEDSLGCLTADTKE 241
[Close]
BLAST of Iroquois-class homeodomain protein IRX-4 vs. Ensembl Human
Match: IRX4 (iroquois homeobox 4 [Source:HGNC Symbol;Acc:HGNC:6129])

HSP 1 Score: 142.124 bits (357), Expect = 4.127e-36
Identity = 70/87 (80.46%), Postives = 75/87 (86.21%), Query Frame = 2 
Query:  695 PYGYIGNPTLDLNSARRKNATRESTSTLKAWLQEHIKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWSPKNRSDD 955
            PY   G  T+D +  RRKNATRE+TSTLKAWLQEH KNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTW P+N+  D
Sbjct:  133 PYDRYG--TMD-SGTRRKNATRETTSTLKAWLQEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWPPRNKCAD 216
[Close]
BLAST of Iroquois-class homeodomain protein IRX-4 vs. Ensembl Human
Match: IRX4 (iroquois homeobox 4 [Source:HGNC Symbol;Acc:HGNC:6129])

HSP 1 Score: 142.124 bits (357), Expect = 4.127e-36
Identity = 70/87 (80.46%), Postives = 75/87 (86.21%), Query Frame = 2 
Query:  695 PYGYIGNPTLDLNSARRKNATRESTSTLKAWLQEHIKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWSPKNRSDD 955
            PY   G  T+D +  RRKNATRE+TSTLKAWLQEH KNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTW P+N+  D
Sbjct:  133 PYDRYG--TMD-SGTRRKNATRETTSTLKAWLQEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWPPRNKCAD 216
[Close]
BLAST of Iroquois-class homeodomain protein IRX-4 vs. Ensembl Celegans
Match: irx-1 (Putative iroquois-class homeodomain protein irx-1 [Source:UniProtKB/Swiss-Prot;Acc:Q93348])

HSP 1 Score: 119.398 bits (298), Expect = 2.233e-29
Identity = 56/89 (62.92%), Postives = 68/89 (76.40%), Query Frame = 2 
Query:  692 NPYGYIGNPTLDLNSARRKNATRESTSTLKAWLQEHIKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWSPKNRSDDA 958
            +PYG        L+  +++NATRE+T+ LK WL  H KNPYP+K +K+MLA+ T MTLTQVSTWFANARRRLKKENKMTWSP+NR  D 
Sbjct:  110 HPYG--------LDGIKKRNATREATAPLKDWLHSHRKNPYPSKADKVMLAVGTGMTLTQVSTWFANARRRLKKENKMTWSPQNRRGDG 190
[Close]
BLAST of Iroquois-class homeodomain protein IRX-4 vs. Ensembl Celegans
Match: unc-62 (Homeobox protein unc-62 [Source:UniProtKB/Swiss-Prot;Acc:Q9N5D6])

HSP 1 Score: 54.299 bits (129), Expect = 1.447e-7
Identity = 22/54 (40.74%), Postives = 37/54 (68.52%), Query Frame = 2 
Query:  746 KNATRESTSTLKAWLQEHIKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRL 907
            K  ++E+ +  +AWL  ++ +PYP++ +K  LA  T +T+ QV+ WF NARRR+
Sbjct:  360 KVFSKEAITKFRAWLFHNLTHPYPSEEQKKQLAKETGLTILQVNNWFINARRRI 413
[Close]
BLAST of Iroquois-class homeodomain protein IRX-4 vs. Ensembl Celegans
Match: unc-62 (Homeobox protein unc-62 [Source:UniProtKB/Swiss-Prot;Acc:Q9N5D6])

HSP 1 Score: 54.299 bits (129), Expect = 1.447e-7
Identity = 22/54 (40.74%), Postives = 37/54 (68.52%), Query Frame = 2 
Query:  746 KNATRESTSTLKAWLQEHIKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRL 907
            K  ++E+ +  +AWL  ++ +PYP++ +K  LA  T +T+ QV+ WF NARRR+
Sbjct:  360 KVFSKEAITKFRAWLFHNLTHPYPSEEQKKQLAKETGLTILQVNNWFINARRRI 413
[Close]
BLAST of Iroquois-class homeodomain protein IRX-4 vs. Ensembl Celegans
Match: unc-62 (Homeobox protein unc-62 [Source:UniProtKB/Swiss-Prot;Acc:Q9N5D6])

HSP 1 Score: 54.299 bits (129), Expect = 1.532e-7
Identity = 22/54 (40.74%), Postives = 37/54 (68.52%), Query Frame = 2 
Query:  746 KNATRESTSTLKAWLQEHIKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRL 907
            K  ++E+ +  +AWL  ++ +PYP++ +K  LA  T +T+ QV+ WF NARRR+
Sbjct:  397 KVFSKEAITKFRAWLFHNLTHPYPSEEQKKQLAKETGLTILQVNNWFINARRRI 450
[Close]
BLAST of Iroquois-class homeodomain protein IRX-4 vs. Ensembl Celegans
Match: unc-62 (Homeobox protein unc-62 [Source:UniProtKB/Swiss-Prot;Acc:Q9N5D6])

HSP 1 Score: 54.299 bits (129), Expect = 1.532e-7
Identity = 22/54 (40.74%), Postives = 37/54 (68.52%), Query Frame = 2 
Query:  746 KNATRESTSTLKAWLQEHIKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRL 907
            K  ++E+ +  +AWL  ++ +PYP++ +K  LA  T +T+ QV+ WF NARRR+
Sbjct:  397 KVFSKEAITKFRAWLFHNLTHPYPSEEQKKQLAKETGLTILQVNNWFINARRRI 450
[Close]
BLAST of Iroquois-class homeodomain protein IRX-4 vs. Ensembl Fly
Match: caup (gene:FBgn0015919 transcript:FBtr0075909)

HSP 1 Score: 154.066 bits (388), Expect = 6.468e-40
Identity = 88/140 (62.86%), Postives = 99/140 (70.71%), Query Frame = 2 
Query:  614 SAWRSAAHMMAADHNPYATYDNSAWANPYGYIGNPTLDLNSARRKNATRESTSTLKAWLQEHIKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWSPKNRSDDATNSDQETDTKCKETDSDDGLKTDCQ 1033
            SAW SA+         Y +YD +  A  YGY   P  DL +ARRKNATREST+TLKAWL EH KNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTW PKN+++D  +     D   KE D+ DG K   +
Sbjct:  195 SAWTSASLQSTTG---YYSYDPTLAA--YGY--GPNYDL-AARRKNATRESTATLKAWLSEHKKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWEPKNKTEDDDDGMMSDDE--KEKDAGDGGKLSTE 324
[Close]
BLAST of Iroquois-class homeodomain protein IRX-4 vs. Ensembl Fly
Match: mirr (gene:FBgn0014343 transcript:FBtr0075911)

HSP 1 Score: 150.984 bits (380), Expect = 4.833e-39
Identity = 80/131 (61.07%), Postives = 89/131 (67.94%), Query Frame = 2 
Query:  554 PFYSSPQTFTSNNHLCCDFGSAWRSAAHMMAADHNPYATYDNSAWANPYGYIGNPTLDLNSARRKNATRESTSTLKAWLQEHIKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWSPKNR 946
            PFY++P       +L     S W   +         Y  YD +    P+   G   +DLN ARRKNATRE+TSTLKAWL EH KNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTW P+NR
Sbjct:  177 PFYANPAGIDLKENLVAG-ASPWPYPSM--------YHPYDAAFAGYPFNSYG---MDLNGARRKNATRETTSTLKAWLNEHKKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWEPRNR 295
[Close]
BLAST of Iroquois-class homeodomain protein IRX-4 vs. Ensembl Fly
Match: mirr (gene:FBgn0014343 transcript:FBtr0075912)

HSP 1 Score: 150.984 bits (380), Expect = 4.833e-39
Identity = 80/131 (61.07%), Postives = 89/131 (67.94%), Query Frame = 2 
Query:  554 PFYSSPQTFTSNNHLCCDFGSAWRSAAHMMAADHNPYATYDNSAWANPYGYIGNPTLDLNSARRKNATRESTSTLKAWLQEHIKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWSPKNR 946
            PFY++P       +L     S W   +         Y  YD +    P+   G   +DLN ARRKNATRE+TSTLKAWL EH KNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTW P+NR
Sbjct:  177 PFYANPAGIDLKENLVAG-ASPWPYPSM--------YHPYDAAFAGYPFNSYG---MDLNGARRKNATRETTSTLKAWLNEHKKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWEPRNR 295
[Close]
BLAST of Iroquois-class homeodomain protein IRX-4 vs. Ensembl Fly
Match: mirr (gene:FBgn0014343 transcript:FBtr0330077)

HSP 1 Score: 150.984 bits (380), Expect = 5.682e-39
Identity = 80/131 (61.07%), Postives = 89/131 (67.94%), Query Frame = 2 
Query:  554 PFYSSPQTFTSNNHLCCDFGSAWRSAAHMMAADHNPYATYDNSAWANPYGYIGNPTLDLNSARRKNATRESTSTLKAWLQEHIKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWSPKNR 946
            PFY++P       +L     S W   +         Y  YD +    P+   G   +DLN ARRKNATRE+TSTLKAWL EH KNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTW P+NR
Sbjct:  177 PFYANPAGIDLKENLVAG-ASPWPYPSM--------YHPYDAAFAGYPFNSYG---MDLNGARRKNATRETTSTLKAWLNEHKKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWEPRNR 295
[Close]
BLAST of Iroquois-class homeodomain protein IRX-4 vs. Ensembl Fly
Match: ara (gene:FBgn0015904 transcript:FBtr0300551)

HSP 1 Score: 145.591 bits (366), Expect = 4.878e-37
Identity = 77/100 (77.00%), Postives = 83/100 (83.00%), Query Frame = 2 
Query:  698 YGYIGNPTLDLNSARRKNATRESTSTLKAWLQEHIKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWSPKNRSDDATNSDQETDTKCKE 997
            YGY    + DL +ARRKNATREST+TLKAWL EH KNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTW PKNR+DD  ++    D K KE
Sbjct:  239 YGY--GASYDL-AARRKNATRESTATLKAWLNEHKKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWEPKNRTDDDDDALVSDDEKDKE 335
[Close]
BLAST of Iroquois-class homeodomain protein IRX-4 vs. Ensembl Zebrafish
Match: irx6a (iroquois homeobox 6a [Source:ZFIN;Acc:ZDB-GENE-040712-5])

HSP 1 Score: 155.606 bits (392), Expect = 1.666e-41
Identity = 105/229 (45.85%), Postives = 119/229 (51.97%), Query Frame = 2 
Query:  662 YATYDNSAWANPYGYIGNPTLDLN-SARRKNATRESTSTLKAWLQEHIKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWSPKN-----RSDDATNSDQETDTKCKETDSDDGLKTDC-QLDT---LSDQDDLAMKS-----------------SFPSKLNDV---------------------------------------KPKIWSLAHTATAGLF 1150
            Y  YD+S     Y   G  T+D N S RRKNATRE+TSTLK WL EH KNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWSPKN     R +D  + D + +   + +D DD    DC +LD+    S QDDL   S                 SFP  L  +                                       KP+IWSLA TA AG+ 
Sbjct:  126 YYPYDHSLGQYQYDRYG--TVDFNGSTRRKNATRETTSTLKTWLYEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWSPKNKAGDDRKEDLDSKDSKDEQDLQFSDLDDMEDEDCDKLDSDCEKSGQDDLPTSSPPKRDCNPDIPLHSNFPSFPCGLKSLGPLNPDYLDHLGSKPQQQQPSPQSTSINTVALSHFESSEKPRIWSLARTAAAGVV 352
[Close]
BLAST of Iroquois-class homeodomain protein IRX-4 vs. Ensembl Zebrafish
Match: irx6a (iroquois homeobox 6a [Source:ZFIN;Acc:ZDB-GENE-040712-5])

HSP 1 Score: 155.606 bits (392), Expect = 1.666e-41
Identity = 105/229 (45.85%), Postives = 119/229 (51.97%), Query Frame = 2 
Query:  662 YATYDNSAWANPYGYIGNPTLDLN-SARRKNATRESTSTLKAWLQEHIKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWSPKN-----RSDDATNSDQETDTKCKETDSDDGLKTDC-QLDT---LSDQDDLAMKS-----------------SFPSKLNDV---------------------------------------KPKIWSLAHTATAGLF 1150
            Y  YD+S     Y   G  T+D N S RRKNATRE+TSTLK WL EH KNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWSPKN     R +D  + D + +   + +D DD    DC +LD+    S QDDL   S                 SFP  L  +                                       KP+IWSLA TA AG+ 
Sbjct:  126 YYPYDHSLGQYQYDRYG--TVDFNGSTRRKNATRETTSTLKTWLYEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWSPKNKAGDDRKEDLDSKDSKDEQDLQFSDLDDMEDEDCDKLDSDCEKSGQDDLPTSSPPKRDCNPDIPLHSNFPSFPCGLKSLGPLNPDYLDHLGSKPQQQQPSPQSTSINTVALSHFESSEKPRIWSLARTAAAGVV 352
[Close]
BLAST of Iroquois-class homeodomain protein IRX-4 vs. Ensembl Zebrafish
Match: irx4b (iroquois homeobox 4b [Source:ZFIN;Acc:ZDB-GENE-040712-4])

HSP 1 Score: 150.214 bits (378), Expect = 1.042e-39
Identity = 92/180 (51.11%), Postives = 110/180 (61.11%), Query Frame = 2 
Query:  632 AHMMAADHNPYATYDNSAWANPYGYIGNPTLDLNSARRKNATRESTSTLKAWLQEHIKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWSPKNRSDDATNSD---------QETDTKCKETDSDDGLKTDCQLDTL-SDQDDLAMKSSFPSKLNDVKPKIWSLAHTATA 1141
             H      + Y  YD       Y   G  ++D+ + RRKNATRE+TSTLKAWLQEH KNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWSP+N++ D    D         QE   K ++  +D+  K D   D L SD DD  +  S  S+  + KP      H+ T+
Sbjct:  107 GHSRVTQSSAYYPYDYPIGQYSYDRYGYGSVDVGT-RRKNATRETTSTLKAWLQEHKKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWSPRNKNSDEKECDDDQEDLDEAQEEPIKTEQDFNDNHGKDD--TDQLHSDLDDFDLVESDGSEC-ESKPSFVVHVHSETS 282
[Close]
BLAST of Iroquois-class homeodomain protein IRX-4 vs. Ensembl Zebrafish
Match: irx4b (iroquois homeobox 4b [Source:ZFIN;Acc:ZDB-GENE-040712-4])

HSP 1 Score: 150.214 bits (378), Expect = 1.042e-39
Identity = 92/180 (51.11%), Postives = 110/180 (61.11%), Query Frame = 2 
Query:  632 AHMMAADHNPYATYDNSAWANPYGYIGNPTLDLNSARRKNATRESTSTLKAWLQEHIKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWSPKNRSDDATNSD---------QETDTKCKETDSDDGLKTDCQLDTL-SDQDDLAMKSSFPSKLNDVKPKIWSLAHTATA 1141
             H      + Y  YD       Y   G  ++D+ + RRKNATRE+TSTLKAWLQEH KNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWSP+N++ D    D         QE   K ++  +D+  K D   D L SD DD  +  S  S+  + KP      H+ T+
Sbjct:  107 GHSRVTQSSAYYPYDYPIGQYSYDRYGYGSVDVGT-RRKNATRETTSTLKAWLQEHKKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWSPRNKNSDEKECDDDQEDLDEAQEEPIKTEQDFNDNHGKDD--TDQLHSDLDDFDLVESDGSEC-ESKPSFVVHVHSETS 282
[Close]
BLAST of Iroquois-class homeodomain protein IRX-4 vs. Ensembl Zebrafish
Match: irx4b (iroquois homeobox 4b [Source:ZFIN;Acc:ZDB-GENE-040712-4])

HSP 1 Score: 150.214 bits (378), Expect = 1.042e-39
Identity = 92/180 (51.11%), Postives = 110/180 (61.11%), Query Frame = 2 
Query:  632 AHMMAADHNPYATYDNSAWANPYGYIGNPTLDLNSARRKNATRESTSTLKAWLQEHIKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWSPKNRSDDATNSD---------QETDTKCKETDSDDGLKTDCQLDTL-SDQDDLAMKSSFPSKLNDVKPKIWSLAHTATA 1141
             H      + Y  YD       Y   G  ++D+ + RRKNATRE+TSTLKAWLQEH KNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWSP+N++ D    D         QE   K ++  +D+  K D   D L SD DD  +  S  S+  + KP      H+ T+
Sbjct:  107 GHSRVTQSSAYYPYDYPIGQYSYDRYGYGSVDVGT-RRKNATRETTSTLKAWLQEHKKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWSPRNKNSDEKECDDDQEDLDEAQEEPIKTEQDFNDNHGKDD--TDQLHSDLDDFDLVESDGSEC-ESKPSFVVHVHSETS 282
[Close]
BLAST of Iroquois-class homeodomain protein IRX-4 vs. Ensembl Xenopus
Match: lypla1 (lysophospholipase 1 [Source:Xenbase;Acc:XB-GENE-942736])

HSP 1 Score: 152.525 bits (384), Expect = 1.105e-40
Identity = 96/205 (46.83%), Postives = 117/205 (57.07%), Query Frame = 2 
Query:  626 SAAHMMAADHNPYATYDNSAWANPYGYIGNPTLDLN-SARRKNATRESTSTLKAWLQEHIKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWSPKNRSDDATN-----------SDQETDTKCKETDSDDGLKTDCQL-------DTLSDQDDLAMKSSFPSKL------------NDVKPKIWSLAHTATAGL 1147
            S+ H   A    Y  Y++S     Y   G   +D++ S+RRKNATRE+TSTLK WL EH KNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWSPKN++ D               DQ + TK K ++S     ++C L       D   ++ +    S F                   KP+IWSLAHTA + +
Sbjct:  108 SSLHPGIAQPAAYYPYEHSLGQYQYDRFG--AVDISCSSRRKNATRENTSTLKTWLYEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWSPKNKAMDEKKDEKQEDYNSGCEDQGSGTKPKVSNSYRSRSSECNLTPSDTSYDLYCNEANAEDYSGFEKNTLQENSDHLVTYGTTGKPRIWSLAHTAASSI 310
[Close]
BLAST of Iroquois-class homeodomain protein IRX-4 vs. Ensembl Xenopus
Match: fancm (FA complementation group M [Source:Xenbase;Acc:XB-GENE-994655])

HSP 1 Score: 144.821 bits (364), Expect = 1.323e-37
Identity = 77/131 (58.78%), Postives = 92/131 (70.23%), Query Frame = 2 
Query:  692 NPYGYIGNPTLDLNSARRKNATRESTSTLKAWLQEHIKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWSPKNRSDD----------ATNSDQETDTKCKETDS-DDGLKTDCQLDTLSD 1051
            +PYG    P    + A RKNATR++T+TLKAWLQEH KNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTW+P+N+S+D                E    C ET + D+G+     +D+L+D
Sbjct:   97 HPYGSAAYPYQLNDPAYRKNATRDATATLKAWLQEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWAPRNKSEDEDDDEGDGERVKEEQSEKAQDCNETSAEDEGI--SLHVDSLTD 225
[Close]
BLAST of Iroquois-class homeodomain protein IRX-4 vs. Ensembl Xenopus
Match: fancm (FA complementation group M [Source:Xenbase;Acc:XB-GENE-994655])

HSP 1 Score: 144.436 bits (363), Expect = 2.715e-37
Identity = 76/131 (58.02%), Postives = 90/131 (68.70%), Query Frame = 2 
Query:  692 NPYGYIGNPTLDLNSARRKNATRESTSTLKAWLQEHIKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWSPKNRSDD----------ATNSDQETDTKCKETDSDDGLKTDCQLDTLSDQ 1054
            +PYG    P    + A RKNATR++T+TLKAWLQEH KNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTW+P+N+S+D                E    C ET ++D       +D+L+D 
Sbjct:   97 HPYGSAAYPYQLNDPAYRKNATRDATATLKAWLQEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWAPRNKSEDEDDDEGDGERVKEEQSEKAQDCNETSAEDE-GISLHVDSLTDH 226
[Close]
BLAST of Iroquois-class homeodomain protein IRX-4 vs. Ensembl Xenopus
Match: irx4 (iroquois homeobox 4 [Source:NCBI gene;Acc:100038068])

HSP 1 Score: 142.895 bits (359), Expect = 1.517e-36
Identity = 70/86 (81.40%), Postives = 74/86 (86.05%), Query Frame = 2 
Query:  698 YGYIGNPTLDLNSARRKNATRESTSTLKAWLQEHIKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWSPKNRSDD 955
            Y Y    T+D  S RRKNATRE+TSTLKAWLQEH KNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTW P+N+  D
Sbjct:  131 YQYDRYGTMD-GSTRRKNATRETTSTLKAWLQEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWPPRNKCSD 215
[Close]
BLAST of Iroquois-class homeodomain protein IRX-4 vs. Ensembl Xenopus
Match: ndufaf5 (NADH:ubiquinone oxidoreductase complex assembly factor 5 [Source:Xenbase;Acc:XB-GENE-975960])

HSP 1 Score: 141.739 bits (356), Expect = 1.710e-36
Identity = 74/110 (67.27%), Postives = 85/110 (77.27%), Query Frame = 2 
Query:  644 AADHNPYATYDNSAWANPYGY--IGNPTLDLNSARRKNATRESTSTLKAWLQEHIKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWSPKNRSDDATNS 967
            AA  +P+A +       PYG    G+P+      R KNATRESTSTLKAWL EH KNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTW+P++R+D+  N+
Sbjct:   89 AAFSHPHAAF------YPYGQYQFGDPS------RPKNATRESTSTLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWAPRSRTDEEGNA 186
[Close]
BLAST of Iroquois-class homeodomain protein IRX-4 vs. Ensembl Mouse
Match: Irx6 (Iroquois homeobox 6 [Source:MGI Symbol;Acc:MGI:1927642])

HSP 1 Score: 150.214 bits (378), Expect = 1.007e-39
Identity = 82/139 (58.99%), Postives = 95/139 (68.35%), Query Frame = 2 
Query:  656 NPYATYDNSAWANPYGYIGNPTLDLNSA-RRKNATRESTSTLKAWLQEHIKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWSPKNRSDDATNSDQETDT-KCKETDSDDGLKT-DCQLDTLSDQDDL 1063
             P A Y        Y Y     ++L+SA RRKNATRESTS LKAWL EH KNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTW+PKN+  +   +D   D+  C   D+ D   + + +   LSD +DL
Sbjct:  117 QPGAYYPYETTLGQYQYDRYGGVELSSAGRRKNATRESTSALKAWLHEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWAPKNKGGEERKADSGEDSLGCLNGDTKDATASQEARGLRLSDLEDL 255
[Close]
BLAST of Iroquois-class homeodomain protein IRX-4 vs. Ensembl Mouse
Match: Irx6 (Iroquois homeobox 6 [Source:MGI Symbol;Acc:MGI:1927642])

HSP 1 Score: 150.214 bits (378), Expect = 1.061e-39
Identity = 82/139 (58.99%), Postives = 95/139 (68.35%), Query Frame = 2 
Query:  656 NPYATYDNSAWANPYGYIGNPTLDLNSA-RRKNATRESTSTLKAWLQEHIKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWSPKNRSDDATNSDQETDT-KCKETDSDDGLKT-DCQLDTLSDQDDL 1063
             P A Y        Y Y     ++L+SA RRKNATRESTS LKAWL EH KNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTW+PKN+  +   +D   D+  C   D+ D   + + +   LSD +DL
Sbjct:  117 QPGAYYPYETTLGQYQYDRYGGVELSSAGRRKNATRESTSALKAWLHEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWAPKNKGGEERKADSGEDSLGCLNGDTKDATASQEARGLRLSDLEDL 255
[Close]
BLAST of Iroquois-class homeodomain protein IRX-4 vs. Ensembl Mouse
Match: Irx2 (Iroquois homeobox 2 [Source:MGI Symbol;Acc:MGI:1197526])

HSP 1 Score: 135.191 bits (339), Expect = 5.800e-38
Identity = 66/85 (77.65%), Postives = 73/85 (85.88%), Query Frame = 2 
Query:  695 PYGYIGNPTLDLNSARRKNATRESTSTLKAWLQEHIKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWSPKNRS 949
            PYG    P    + A RKNATR++T+TLKAWL EH KNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTW+P+N+S
Sbjct:    9 PYGSAAYPYQLNDPAYRKNATRDATATLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWAPRNKS 93
[Close]
BLAST of Iroquois-class homeodomain protein IRX-4 vs. Ensembl Mouse
Match: Irx2 (Iroquois homeobox 2 [Source:MGI Symbol;Acc:MGI:1197526])

HSP 1 Score: 144.05 bits (362), Expect = 2.546e-37
Identity = 76/126 (60.32%), Postives = 93/126 (73.81%), Query Frame = 2 
Query:  692 NPYGYIGNPTLDLNSARRKNATRESTSTLKAWLQEHIKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWSPKNRSDDATNSDQETDTKCKETDSD---DGLKTDCQLDTLSDQDD 1060
            +PYG    P    + A RKNATR++T+TLKAWL EH KNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTW+P+N+S+D    + +  ++ KE  SD   DG +T  + + +S   D
Sbjct:  102 HPYGSAAYPYQLNDPAYRKNATRDATATLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWAPRNKSEDEDEDEGDA-SRSKEESSDKAQDGTETSAEDEGISLHVD 226
[Close]
BLAST of Iroquois-class homeodomain protein IRX-4 vs. Ensembl Mouse
Match: Irx4 (Iroquois homeobox 4 [Source:MGI Symbol;Acc:MGI:1355275])

HSP 1 Score: 142.51 bits (358), Expect = 1.528e-36
Identity = 72/98 (73.47%), Postives = 79/98 (80.61%), Query Frame = 2 
Query:  662 YATYDNSAWANPYGYIGNPTLDLNSARRKNATRESTSTLKAWLQEHIKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWSPKNRSDD 955
            Y  Y+ +    PY   G  T+D +  RRKNATRE+TSTLKAWLQEH KNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTW P+N+  D
Sbjct:  123 YYPYEPALSQYPYDRYG--TVD-SGTRRKNATRETTSTLKAWLQEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWPPRNKCAD 217
[Close]
BLAST of Iroquois-class homeodomain protein IRX-4 vs. UniProt/SwissProt
Match: sp|P54269|CAUP_DROME (Homeobox protein caupolican OS=Drosophila melanogaster OX=7227 GN=caup PE=2 SV=2)

HSP 1 Score: 154.066 bits (388), Expect = 6.483e-39
Identity = 88/140 (62.86%), Postives = 99/140 (70.71%), Query Frame = 2 
Query:  614 SAWRSAAHMMAADHNPYATYDNSAWANPYGYIGNPTLDLNSARRKNATRESTSTLKAWLQEHIKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWSPKNRSDDATNSDQETDTKCKETDSDDGLKTDCQ 1033
            SAW SA+         Y +YD +  A  YGY   P  DL +ARRKNATREST+TLKAWL EH KNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTW PKN+++D  +     D   KE D+ DG K   +
Sbjct:  195 SAWTSASLQSTTG---YYSYDPTLAA--YGY--GPNYDL-AARRKNATRESTATLKAWLSEHKKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWEPKNKTEDDDDGMMSDDE--KEKDAGDGGKLSTE 324
[Close]
BLAST of Iroquois-class homeodomain protein IRX-4 vs. UniProt/SwissProt
Match: sp|Q9ER75|IRX6_MOUSE (Iroquois-class homeodomain protein IRX-6 OS=Mus musculus OX=10090 GN=Irx6 PE=2 SV=2)

HSP 1 Score: 150.214 bits (378), Expect = 7.423e-39
Identity = 82/139 (58.99%), Postives = 95/139 (68.35%), Query Frame = 2 
Query:  656 NPYATYDNSAWANPYGYIGNPTLDLNSA-RRKNATRESTSTLKAWLQEHIKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWSPKNRSDDATNSDQETDT-KCKETDSDDGLKT-DCQLDTLSDQDDL 1063
             P A Y        Y Y     ++L+SA RRKNATRESTS LKAWL EH KNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTW+PKN+  +   +D   D+  C   D+ D   + + +   LSD +DL
Sbjct:  117 QPGAYYPYETTLGQYQYDRYGGVELSSAGRRKNATRESTSALKAWLHEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWAPKNKGGEERKADSGEDSLGCLNGDTKDATASQEARGLRLSDLEDL 255
[Close]
BLAST of Iroquois-class homeodomain protein IRX-4 vs. UniProt/SwissProt
Match: sp|Q66IK1|IRX2_XENTR (Iroquois-class homeodomain protein irx-2 OS=Xenopus tropicalis OX=8364 GN=irx2 PE=2 SV=1)

HSP 1 Score: 144.821 bits (364), Expect = 7.007e-37
Identity = 77/131 (58.78%), Postives = 92/131 (70.23%), Query Frame = 2 
Query:  692 NPYGYIGNPTLDLNSARRKNATRESTSTLKAWLQEHIKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWSPKNRSDD----------ATNSDQETDTKCKETDS-DDGLKTDCQLDTLSD 1051
            +PYG    P    + A RKNATR++T+TLKAWLQEH KNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTW+P+N+S+D                E    C ET + D+G+     +D+L+D
Sbjct:   97 HPYGSAAYPYQLNDPAYRKNATRDATATLKAWLQEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWAPRNKSEDEDDDEGDGERVKEEQSEKAQDCNETSAEDEGI--SLHVDSLTD 225
[Close]
BLAST of Iroquois-class homeodomain protein IRX-4 vs. UniProt/SwissProt
Match: sp|Q9BZI1|IRX2_HUMAN (Iroquois-class homeodomain protein IRX-2 OS=Homo sapiens OX=9606 GN=IRX2 PE=1 SV=2)

HSP 1 Score: 145.206 bits (365), Expect = 8.250e-37
Identity = 78/131 (59.54%), Postives = 94/131 (71.76%), Query Frame = 2 
Query:  692 NPYGYIGNPTLDLNSARRKNATRESTSTLKAWLQEHIKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWSPKNRS-------DDATNSDQETDTKCKE----TDSDDGLKTDCQLDTLSD 1051
            +PYG    P    + A RKNATR++T+TLKAWL EH KNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTW+P+N+S        DAT S  E+  K +E    +  D+G+     +D+L+D
Sbjct:  101 HPYGSAAYPYQLNDPAYRKNATRDATATLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWAPRNKSEDEDEDEGDATRSKDESPDKAQEGTETSAEDEGI--SLHVDSLTD 229
[Close]
BLAST of Iroquois-class homeodomain protein IRX-4 vs. UniProt/SwissProt
Match: sp|P78412|IRX6_HUMAN (Iroquois-class homeodomain protein IRX-6 OS=Homo sapiens OX=9606 GN=IRX6 PE=1 SV=3)

HSP 1 Score: 144.05 bits (362), Expect = 1.106e-36
Identity = 75/132 (56.82%), Postives = 90/132 (68.18%), Query Frame = 2 
Query:  626 SAAHMMAADHNPYATYDNSAWANPYGYIGNPTLDLNSA-RRKNATRESTSTLKAWLQEHIKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWSPKNRSDDATNSD--QETDTKCKETDSDD 1012
            +A    ++   P A Y        Y Y     ++L+ A RRKNATRE+TSTLKAWL EH KNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTW+PKN+  +   ++  +E    C   D+ +
Sbjct:  110 AAGSFTSSLAQPGAYYPYERTLGQYQYERYGAVELSGAGRRKNATRETTSTLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWAPKNKGGEERKAEGGEEDSLGCLTADTKE 241
[Close]
BLAST of Iroquois-class homeodomain protein IRX-4 vs. TrEMBL
Match: A0A0A9W3F2 (Homeobox protein araucan OS=Lygus hesperus OX=30085 GN=ara_2 PE=4 SV=1)

HSP 1 Score: 162.54 bits (410), Expect = 7.490e-41
Identity = 81/119 (68.07%), Postives = 93/119 (78.15%), Query Frame = 2 
Query:  662 YATYDNSAWANPYGYIGNPTLDLNSARRKNATRESTSTLKAWLQEHIKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWSPKNRSDDATNSDQETDTKCKETDSDDGL 1018
            Y  YD +  A P+   G   +DLN ARRKNATRE+TSTLKAWL EH KNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTW P+NR DD  N+++E+ +  K  ++ D L
Sbjct:  153 YHPYDAAFAAYPFNGYG---MDLNGARRKNATRETTSTLKAWLNEHKKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWEPRNRVDDEDNNNEESSSGRKSAENKDAL 268
[Close]
BLAST of Iroquois-class homeodomain protein IRX-4 vs. TrEMBL
Match: A0A5A9PQZ7 (Iroquois-class homeodomain protein IRX-6 Homeodomain protein IRXB3 OS=Triplophysa tibetana OX=1572043 GN=E1301_Tti012659 PE=4 SV=1)

HSP 1 Score: 161.384 bits (407), Expect = 2.708e-40
Identity = 113/273 (41.39%), Postives = 136/273 (49.82%), Query Frame = 2 
Query:  662 YATYDNSAWANPYGYIGNPTLDLN-SARRKNATRESTSTLKAWLQEHIKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWSPKNRSDDATNSDQE----TDTKCKETDSDDGLKTDCQLDTLSDQDDLAMK-------------SSFPSKLNDV--------------------------------------KPKIWSLAHTATAGLF-----SMPLQSYPGHCTDGSAEDPQNNSNINQYPANIGMP--LISSHPLYQQGF 1291
            Y  YD+S     Y   G  T+D N SARRKNATRE+TSTLK WL EH KNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWSPKN++D   + D+     +D    E +  D L +DC+    S QDD+                SSFP  L  +                                      KP+IWSLA TA AG+         +++ PG C   +   P            +  P  L ++  LYQ+G 
Sbjct:  134 YYPYDHSLGQYQYDRYG--TVDFNGSARRKNATRETTSTLKTWLYEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWSPKNKADSKDSKDERDLQFSDLDDIEDEDCDKLDSDCE---KSGQDDIPASSPPKRDCNPNLNFSSFPCGLKSLGALNPDYLDPLGSKAQQQPSPQSTSISTMALSHFETSQKPRIWSLARTAAAGVVLGAHHGGDVRTGPGDCQMQTVRIPTVGGGQCGELEGLQDPINLSNTESLYQEGL 401
[Close]
BLAST of Iroquois-class homeodomain protein IRX-4 vs. TrEMBL
Match: A0A2T7NIF5 (Homeobox domain-containing protein OS=Pomacea canaliculata OX=400727 GN=C0Q70_19120 PE=4 SV=1)

HSP 1 Score: 155.992 bits (393), Expect = 3.322e-40
Identity = 82/117 (70.09%), Postives = 92/117 (78.63%), Query Frame = 2 
Query:  617 AWRSAAHMMAADHNPYATYDNSAWANPYGYIGNPTLDLNSARRKNATRESTSTLKAWLQEHIKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWSPKNRSDDATNS 967
            AWR+ A   A  ++P + Y       PYG  G   LDLNS RRKNATRE+T+TLKAWL EH KNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWSP+NRS+D + +
Sbjct:   94 AWRTLAAQPAFPYDPMSLY-------PYG-AGYGGLDLNS-RRKNATRENTNTLKAWLYEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWSPRNRSEDGSEA 201
[Close]
BLAST of Iroquois-class homeodomain protein IRX-4 vs. TrEMBL
Match: E9GNW3 (Homeobox domain-containing protein (Fragment) OS=Daphnia pulex OX=6669 GN=DAPPUDRAFT_28797 PE=4 SV=1)

HSP 1 Score: 149.443 bits (376), Expect = 4.137e-40
Identity = 72/86 (83.72%), Postives = 77/86 (89.53%), Query Frame = 2 
Query:  698 YGYIGNPTLDLNSARRKNATRESTSTLKAWLQEHIKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWSPKNRSDD 955
            YG  G   +DLN +RRKNATRE+T+TLKAWL EH KNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTW PKNR+DD
Sbjct:    1 YGRYG---MDLNGSRRKNATRETTATLKAWLSEHKKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWEPKNRNDD 83
[Close]
BLAST of Iroquois-class homeodomain protein IRX-4 vs. TrEMBL
Match: A0A3Q3JHM2 (Iroquois homeobox 6a OS=Monopterus albus OX=43700 PE=4 SV=1)

HSP 1 Score: 160.229 bits (404), Expect = 6.597e-40
Identity = 98/176 (55.68%), Postives = 112/176 (63.64%), Query Frame = 2 
Query:  662 YATYDNSAWANPYGYIGNPTLDLN-SARRKNATRESTSTLKAWLQEHIKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWSPKN-----RSDDATNSDQETDTK----CKE-------------TDSDDGLKTDCQLDTLSDQDDL--AMKSSFPSKLNDVKPKI 1114
            Y  YD+S    PY   G  T+D + +ARRKNATRE+TSTLK WL EH KNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWSPKN     R DD   SDQ+  TK    CKE              D  D L +DC+   ++D+ DL  AM  S P +  D   ++
Sbjct:  104 YYPYDHSLGQYPYDRYG--TVDFSGTARRKNATRETTSTLKTWLYEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWSPKNKASDDRKDDLNKSDQDCVTKESNDCKEEKDLHLSDLEDMDEDDCDKLDSDCE-KVVADEQDLQRAMAVSGPPQKRDCSSEL 276
[Close]
BLAST of Iroquois-class homeodomain protein IRX-4 vs. Ensembl Cavefish
Match: irx4b (iroquois-class homeodomain protein irx-4-B [Source:NCBI gene;Acc:103030452])

HSP 1 Score: 153.295 bits (386), Expect = 7.015e-41
Identity = 83/135 (61.48%), Postives = 98/135 (72.59%), Query Frame = 2 
Query:  698 YGYIGNPTLDLNSARRKNATRESTSTLKAWLQEHIKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWSPKNRSDDATNSDQETD--------TKCKETDSDDGLKTDCQLDTLSDQDDLAMKSS 1078
            YGY    ++D+ S RRKNATRE+TSTLKAWLQEH +NPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWSP+N++ D    D+++D        T   E +SDD  + D      SD +DL +  S
Sbjct:  127 YGY---SSMDV-STRRKNATRETTSTLKAWLQEHKRNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWSPRNKASDEKGCDEDSDDVEGSQEETMKSEKESDDNPRADDTDLPQSDLEDLDLTES 257
[Close]
BLAST of Iroquois-class homeodomain protein IRX-4 vs. Ensembl Cavefish
Match: irx4b (iroquois-class homeodomain protein irx-4-B [Source:NCBI gene;Acc:103030452])

HSP 1 Score: 152.525 bits (384), Expect = 1.198e-40
Identity = 83/135 (61.48%), Postives = 98/135 (72.59%), Query Frame = 2 
Query:  698 YGYIGNPTLDLNSARRKNATRESTSTLKAWLQEHIKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWSPKNRSDDATNSDQETD--------TKCKETDSDDGLKTDCQLDTLSDQDDLAMKSS 1078
            YGY    ++D+ S RRKNATRE+TSTLKAWLQEH +NPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWSP+N++ D    D+++D        T   E +SDD  + D      SD +DL +  S
Sbjct:  135 YGY---SSMDV-STRRKNATRETTSTLKAWLQEHKRNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWSPRNKASDEKGCDEDSDDVEGSQEETMKSEKESDDNPRADDTDLPQSDLEDLDLTES 265
[Close]
BLAST of Iroquois-class homeodomain protein IRX-4 vs. Ensembl Cavefish
Match: irx4a (iroquois-class homeodomain protein irx-4 [Source:NCBI gene;Acc:103025323])

HSP 1 Score: 145.976 bits (367), Expect = 3.910e-38
Identity = 86/157 (54.78%), Postives = 96/157 (61.15%), Query Frame = 2 
Query:  611 GSAWRSAAHMMAADHNPYATYDNSAWANPYGYIGNPTLDLNSARRKNATRESTSTLKAWLQEHIKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWSPKNRSDDATN------SDQETDTKCKETDSDDGLKTDCQLDTLSDQDDL 1063
            G+A   A    AA + PY         + YG +   T      RRKNATRE+TSTLKAWLQEH KNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTW P+N+  D           QE   K +  D +   + D  L  LSD DD 
Sbjct:  100 GTASAHAGITQAATYYPYDPTLGQYQYDRYGSMDGGT------RRKNATRETTSTLKAWLQEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWPPRNKCSDEKRYGEDEEGSQEDQIKSETNDDESRSREDKDLQ-LSDLDDF 249
[Close]
BLAST of Iroquois-class homeodomain protein IRX-4 vs. Ensembl Cavefish
Match: irx3b (iroquois homeobox 3 [Source:NCBI gene;Acc:103035229])

HSP 1 Score: 142.51 bits (358), Expect = 9.708e-38
Identity = 71/92 (77.17%), Postives = 78/92 (84.78%), Query Frame = 2 
Query:  695 PYGY--IGNPTLDLNSARRKNATRESTSTLKAWLQEHIKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWSPKNRSDDATN 964
            PYG+  +G+P+      R KNATRESTSTLKAWL EH KNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTW+PK R+D+  N
Sbjct:   88 PYGHYQLGDPS------RPKNATRESTSTLKAWLSEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWAPKTRTDEDGN 173
[Close]
BLAST of Iroquois-class homeodomain protein IRX-4 vs. Ensembl Cavefish
Match: irx5b (iroquois homeobox 5b [Source:ZFIN;Acc:ZDB-GENE-040628-5])

HSP 1 Score: 139.043 bits (349), Expect = 4.067e-36
Identity = 80/171 (46.78%), Postives = 102/171 (59.65%), Query Frame = 2 
Query:  530 SISPNTNIPFYSSPQTFTSNNHLCCDFGSAWRSAAHMMAADHNPYATYDNSAWANPYGYIGNPTLDLNSARRKNATRESTSTLKAWLQEHIKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWSPKNRS---------DDATNSDQETDTKCKETDSDDG 1015
            + +P      ++SP  F++       +G+   + +  + + ++P      S    PYG    P   L+ A RKNATR++T+TLKAWL EH KNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTW  ++RS         D   + D E   K  ET  + G
Sbjct:   55 AFAPYAGSAAFTSPAPFSA-----LQYGAEPAALSAFVGSPYDPGPGVGGSVVFPPYGGALGPFPALDPAYRKNATRDATATLKAWLSEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWCSRSRSEDEEEEENIDLEKHEDDEEPLKASETTPEPG 220
[Close]
BLAST of Iroquois-class homeodomain protein IRX-4 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002620.1 (pep scaffold:Pmarinus_7.0:GL484724:8057:10194:-1 gene:ENSPMAG00000002391.1 transcript:ENSPMAT00000002620.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 131.339 bits (329), Expect = 1.304e-36
Identity = 71/101 (70.30%), Postives = 76/101 (75.25%), Query Frame = 2 
Query:  695 PYGYIGNPTLDLNSARRKNATRESTSTLKAWLQEHIKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWSPKNRSDDATNSDQETDTKCKE 997
            PYG  G    D   A RKNATR++T+TLKAWL EH KNPYPTKGEKIMLAIIT+MTLTQVSTWFANARRRLKKENKMTW  K RSDD    D    +  KE
Sbjct:   27 PYGAGGCGVAD--PAFRKNATRDATATLKAWLNEHRKNPYPTKGEKIMLAIITRMTLTQVSTWFANARRRLKKENKMTWVTKARSDDELEDDDNDGSGGKE 125
[Close]
BLAST of Iroquois-class homeodomain protein IRX-4 vs. Ensembl Sea Lamprey
Match: mkxb (mohawk homeobox b [Source:ZFIN;Acc:ZDB-GENE-080513-2])

HSP 1 Score: 72.7886 bits (177), Expect = 8.017e-15
Identity = 34/69 (49.28%), Postives = 49/69 (71.01%), Query Frame = 2 
Query:  743 RKNATRESTSTLKAWLQEHIKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLK---KENKMTWSPK 940
            ++ A ++    LK WL +H  NPYPTK EKI+LA+ + MTL QVS WFANARRRLK   ++ +++W+ +
Sbjct:    5 KRQALQDMARPLKHWLYKHRHNPYPTKTEKILLALGSHMTLVQVSNWFANARRRLKNTVRQPELSWAMR 73
[Close]
BLAST of Iroquois-class homeodomain protein IRX-4 vs. Ensembl Sea Lamprey
Match: pknox2 (pbx/knotted 1 homeobox 2 [Source:ZFIN;Acc:ZDB-GENE-031118-112])

HSP 1 Score: 59.3066 bits (142), Expect = 7.832e-10
Identity = 28/63 (44.44%), Postives = 41/63 (65.08%), Query Frame = 2 
Query:  725 DLNSARRKNAT--RESTSTLKAWLQEHIKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRL 907
            D   AR K     + +T+ +++WL +HI +PYPT+ EK  +A  T +TL QV+ WF NARRR+
Sbjct:  254 DDKRARLKRGVLPKHATTVMRSWLFQHIVHPYPTEDEKRQIANQTNLTLLQVNNWFINARRRI 316
[Close]
BLAST of Iroquois-class homeodomain protein IRX-4 vs. Ensembl Yeast
Match: CUP9 (Homeodomain-containing transcriptional repressor; regulates expression of PTR2, which encodes a major peptide transporter; imported peptides activate ubiquitin-dependent proteolysis, resulting in degradation of Cup9p and de-repression of PTR2 transcription; CUP9 has a paralog, TOS8, that arose from the whole genome duplication; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000006098])

HSP 1 Score: 63.929 bits (154), Expect = 1.037e-11
Identity = 29/58 (50.00%), Postives = 35/58 (60.34%), Query Frame = 2 
Query:  731 NSARRKNATRESTSTLKAWLQEHIKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRR 904
            NS RR N  +E+   L  WL  H+ NPYPT+ EK  L I T +T  Q+S WF N RRR
Sbjct:  162 NSGRRSNLPKETVQILNTWLLNHLNNPYPTQQEKRELLIKTGLTKIQLSNWFINVRRR 219
[Close]
BLAST of Iroquois-class homeodomain protein IRX-4 vs. Ensembl Yeast
Match: TOS8 (Homeodomain-containing protein and putative transcription factor; found associated with chromatin; target of SBF transcription factor; induced during meiosis and under cell-damaging conditions; TOS8 has a paralog, CUP9, that arose from the whole genome duplication [Source:SGD;Acc:S000003064])

HSP 1 Score: 60.077 bits (144), Expect = 1.480e-10
Identity = 27/56 (48.21%), Postives = 33/56 (58.93%), Query Frame = 2 
Query:  737 ARRKNATRESTSTLKAWLQEHIKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRR 904
             +R N  + + S L  WL EH+ NPYPT  EK  L   T +T  Q+S WF NARRR
Sbjct:  196 GKRSNLPKATVSILNKWLHEHVNNPYPTVQEKRELLAKTGLTKLQISNWFINARRR 251
[Close]
BLAST of Iroquois-class homeodomain protein IRX-4 vs. Ensembl Nematostella
Match: EDO41982 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S2T4])

HSP 1 Score: 130.954 bits (328), Expect = 2.905e-37
Identity = 65/70 (92.86%), Postives = 68/70 (97.14%), Query Frame = 2 
Query:  737 ARRKNATRESTSTLKAWLQEHIKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWSPKNR 946
            ARRKNATRE+TSTLKAWL EH KNPYPTKGEKIMLAI+TKMTLTQVSTWFANARRRLKKENKMTWSP+NR
Sbjct:    1 ARRKNATRETTSTLKAWLFEHRKNPYPTKGEKIMLAILTKMTLTQVSTWFANARRRLKKENKMTWSPRNR 70
[Close]
BLAST of Iroquois-class homeodomain protein IRX-4 vs. Ensembl Nematostella
Match: EDO39375 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SAC9])

HSP 1 Score: 62.003 bits (149), Expect = 9.971e-11
Identity = 39/117 (33.33%), Postives = 58/117 (49.57%), Query Frame = 2 
Query:  572 QTFTSNNHLCCDFGSAWRSAAHMMAADHNP-----YATYDNSAWANPYGYIGNPTLDLNSARRKNATRESTSTLKAWLQEHIKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRL 907
            QTF     L      A+ + +    A   P      AT      A+P  Y    +  + S +R    +++TS +K WL +HI +PYPT+ EK  +A  T +T+ QV+ WF NARRR+
Sbjct:  140 QTFIQQAQLLAPQDVAYYTTSPCTIAMATPPNISVIATQVQQQQASPMSYTPQQSATVKS-KRGVLPKQATSIMKTWLFQHIMHPYPTEDEKRSIAQQTNLTILQVNNWFINARRRI 255
[Close]
BLAST of Iroquois-class homeodomain protein IRX-4 vs. Ensembl Nematostella
Match: EDO36439 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SIN3])

HSP 1 Score: 56.6102 bits (135), Expect = 6.387e-9
Identity = 24/56 (42.86%), Postives = 39/56 (69.64%), Query Frame = 2 
Query:  740 RRKNATRESTSTLKAWLQEHIKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRL 907
            +R    + +T+ +KAWL +H+ +PYP++ +K  LA  T +T+ QV+ WF NARRR+
Sbjct:  241 KRGIFPKAATNIMKAWLFQHLTHPYPSEEQKRSLAQETGLTILQVNNWFINARRRI 296
[Close]
BLAST of Iroquois-class homeodomain protein IRX-4 vs. Ensembl Nematostella
Match: EDO41178 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S544])

HSP 1 Score: 52.373 bits (124), Expect = 9.096e-9
Identity = 24/56 (42.86%), Postives = 35/56 (62.50%), Query Frame = 2 
Query:  740 RRKNATRESTSTLKAWLQEHIKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRL 907
            RR N  ++S + L+ WL EH  N YP++ EK  L+    +++ QV  WF NARRR+
Sbjct:   19 RRGNLPKDSVNVLRLWLWEHRFNAYPSEAEKQYLSKAANLSVLQVCNWFINARRRI 74
[Close]
BLAST of Iroquois-class homeodomain protein IRX-4 vs. Ensembl Nematostella
Match: EDO43361 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RYQ8])

HSP 1 Score: 47.7506 bits (112), Expect = 4.842e-6
Identity = 21/58 (36.21%), Postives = 35/58 (60.34%), Query Frame = 2 
Query:  740 RRKNATRESTSTLKAWLQEHIKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKK 913
            +R+N ++++T  L  +   H+ NPYP++  K  LA    +++ Q+S WF N R R KK
Sbjct:  201 KRRNFSKQATEILNEYFYSHLSNPYPSEEAKEELARKCNISVAQISNWFGNKRIRYKK 258
[Close]
BLAST of Iroquois-class homeodomain protein IRX-4 vs. Ensembl Medaka
Match: irx6a (iroquois homeobox 6 [Source:NCBI gene;Acc:101173209])

HSP 1 Score: 152.525 bits (384), Expect = 1.901e-40
Identity = 83/121 (68.60%), Postives = 90/121 (74.38%), Query Frame = 2 
Query:  662 YATYDNSAWANPYGYIGNPTLDLN-SARRKNATRESTSTLKAWLQEHIKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWSPKN-----RSDDATNSDQET---DTKCKE 997
            Y  YD+S     Y   G  T+D N +ARRKNATRE+TSTLK WL EH KNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWSPKN     R DD + SDQ+     + CKE
Sbjct:  102 YYPYDHSLGQYQYDRYG--TVDFNGTARRKNATRETTSTLKTWLYEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWSPKNKTSDDRKDDLSKSDQDITKNSSDCKE 220
[Close]
BLAST of Iroquois-class homeodomain protein IRX-4 vs. Ensembl Medaka
Match: irx6a (iroquois homeobox 6 [Source:NCBI gene;Acc:101173209])

HSP 1 Score: 152.91 bits (385), Expect = 1.923e-40
Identity = 83/121 (68.60%), Postives = 90/121 (74.38%), Query Frame = 2 
Query:  662 YATYDNSAWANPYGYIGNPTLDLN-SARRKNATRESTSTLKAWLQEHIKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWSPKN-----RSDDATNSDQET---DTKCKE 997
            Y  YD+S     Y   G  T+D N +ARRKNATRE+TSTLK WL EH KNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWSPKN     R DD + SDQ+     + CKE
Sbjct:  116 YYPYDHSLGQYQYDRYG--TVDFNGTARRKNATRETTSTLKTWLYEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWSPKNKTSDDRKDDLSKSDQDITKNSSDCKE 234
[Close]
BLAST of Iroquois-class homeodomain protein IRX-4 vs. Ensembl Medaka
Match: irx4a (iroquois-class homeodomain protein irx-4-like [Source:NCBI gene;Acc:101159378])

HSP 1 Score: 147.902 bits (372), Expect = 7.833e-39
Identity = 86/152 (56.58%), Postives = 97/152 (63.82%), Query Frame = 2 
Query:  626 SAAHMMAADHNPYATYDNSAWANPYGYIGNPTLDLNSARRKNATRESTSTLKAWLQEHIKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWSPKN------RSDDATNSDQETDTKCKETDSDDGLKTDCQLDTLSDQDDL 1063
            ++AH        Y  YD +     Y   G  ++D    RRKNATRE+TSTLKAWLQEH KNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTW P+N      R DD  +  QE   K +  D +   + D  L  LSD DD 
Sbjct:  109 ASAHAGITQATAYYPYDPTLGQYQYDRYG--SMD-GGTRRKNATRETTSTLKAWLQEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWPPRNKGSEEKRYDDDEDGSQEEQIKSENNDDETRSRPDKDLQ-LSDLDDF 256
[Close]
BLAST of Iroquois-class homeodomain protein IRX-4 vs. Ensembl Medaka
Match: irx3a (iroquois homeobox 3 [Source:NCBI gene;Acc:101162111])

HSP 1 Score: 146.362 bits (368), Expect = 1.504e-38
Identity = 76/111 (68.47%), Postives = 85/111 (76.58%), Query Frame = 2 
Query:  695 PYGY--IGNPTLDLNSARRKNATRESTSTLKAWLQEHIKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWSPKNRSDDATN---SDQETDTKCKETDSDD 1012
            PYG    G+P+      R KNATRESTSTLKAWL EH KNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTW+P+NR+D+  N   SD E +   K  D ++
Sbjct:   99 PYGQYQFGDPS------RPKNATRESTSTLKAWLSEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWAPRNRTDEEGNVYTSDHEGEEGDKREDEEE 203
[Close]
BLAST of Iroquois-class homeodomain protein IRX-4 vs. Ensembl Medaka
Match: irx2a (iroquois homeobox 2 [Source:NCBI gene;Acc:101162396])

HSP 1 Score: 147.517 bits (371), Expect = 1.652e-38
Identity = 79/132 (59.85%), Postives = 94/132 (71.21%), Query Frame = 2 
Query:  692 NPYGYIGNPTLDLNSARRKNATRESTSTLKAWLQEHIKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWSPKNRS------------DDATNSDQETDTKCKETDSDDGLKTDCQLDTLSD 1051
            +PYG  G P    + A RKNATR++T+TLKAWLQEH KNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTW+P+N+S             DA  SD+  D   + +  D+G+     +DTL+D
Sbjct:   98 HPYGSPGYPYQLNDPAYRKNATRDATATLKAWLQEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWAPRNKSEDEDEEDGDGERKDAERSDKTLDN-SEASAEDEGI--SLHVDTLTD 226
[Close]
BLAST of Iroquois-class homeodomain protein IRX-4 vs. Planmine SMEST
Match: SMESG000061184.1 (SMESG000061184.1)

HSP 1 Score: 740.725 bits (1911), Expect = 0.000e+0
Identity = 397/398 (99.75%), Postives = 398/398 (100.00%), Query Frame = 2 
Query:  224 MHSAYSSLINSIPGQISLSGGIPDQINPIFNYSSLQTQQNNDPSSXXXXXXXXXXXXXXXXXXXXXHPSTSPNHXXXXXXXXXXXXXXXXAEQPPAPTFGPDSISPNTNIPFYSSPQTFTSNNHLCCDFGSAWRSAAHMMAADHNPYATYDNSAWANPYGYIGNPTLDLNSARRKNATRESTSTLKAWLQEHIKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWSPKNRSDDATNSDQETDTKCKETDSDDGLKTDCQLDTLSDQDDLAMKSSFPSKLNDVKPKIWSLAHTATAGLFSMPLQSYPGHCTDGSAEDPQNNSNINQYPANIGMPLISSHPLYQQGFFHHIDLPNQLNGCQDNKQYSHLYHQQNPNNFFNHSQKRSEML 1417
            MHSAYSSLINSIPGQISLSGGIPDQINPIFNYSSLQTQQNNDPSSLLNLYNPAYAAAAQSRLLSSLHPSTSPNHSNINSTDTSTVSSITSAEQPPAPTFGPDSISPNTNIPFYSSPQTFT+NNHLCCDFGSAWRSAAHMMAADHNPYATYDNSAWANPYGYIGNPTLDLNSARRKNATRESTSTLKAWLQEHIKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWSPKNRSDDATNSDQETDTKCKETDSDDGLKTDCQLDTLSDQDDLAMKSSFPSKLNDVKPKIWSLAHTATAGLFSMPLQSYPGHCTDGSAEDPQNNSNINQYPANIGMPLISSHPLYQQGFFHHIDLPNQLNGCQDNKQYSHLYHQQNPNNFFNHSQKRSEML
Sbjct:    1 MHSAYSSLINSIPGQISLSGGIPDQINPIFNYSSLQTQQNNDPSSLLNLYNPAYAAAAQSRLLSSLHPSTSPNHSNINSTDTSTVSSITSAEQPPAPTFGPDSISPNTNIPFYSSPQTFTNNNHLCCDFGSAWRSAAHMMAADHNPYATYDNSAWANPYGYIGNPTLDLNSARRKNATRESTSTLKAWLQEHIKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWSPKNRSDDATNSDQETDTKCKETDSDDGLKTDCQLDTLSDQDDLAMKSSFPSKLNDVKPKIWSLAHTATAGLFSMPLQSYPGHCTDGSAEDPQNNSNINQYPANIGMPLISSHPLYQQGFFHHIDLPNQLNGCQDNKQYSHLYHQQNPNNFFNHSQKRSEML 398
[Close]
BLAST of Iroquois-class homeodomain protein IRX-4 vs. Planmine SMEST
Match: SMESG000026100.1 (SMESG000026100.1)

HSP 1 Score: 145.206 bits (365), Expect = 1.034e-38
Identity = 83/157 (52.87%), Postives = 103/157 (65.61%), Query Frame = 2 
Query:  722 LDLNS-ARRKNATRESTSTLKAWLQEHIKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWSPKNRSDDATNSDQETDTKCKETDSDDGLKTDCQLDTLSDQDDLAMKSSFPSKLNDV---------------------KPKIWSLA 1126
            +++NS  RRKNATRE+TS LKAWL EH KNPYPTKGEKIMLA+ITKMTLTQVSTWFANARRRLKKENKMTWSP  +S+D  +  ++TD+    +D    L+ D    +L+      +K+ F SKL+ +                     KPKIWS+A
Sbjct:  124 MEMNSHPRRKNATRETTSILKAWLNEHKKNPYPTKGEKIMLAVITKMTLTQVSTWFANARRRLKKENKMTWSPNQKSEDEADDLEDTDS----SDIRSRLQDDPA--SLTKNYSKELKNEFLSKLSAINNLSADISNPKINSNVTSKSTKPKIWSIA 274
[Close]
BLAST of Iroquois-class homeodomain protein IRX-4 vs. Planmine SMEST
Match: SMESG000026100.1 (SMESG000026100.1)

HSP 1 Score: 145.206 bits (365), Expect = 1.361e-38
Identity = 83/157 (52.87%), Postives = 103/157 (65.61%), Query Frame = 2 
Query:  722 LDLNS-ARRKNATRESTSTLKAWLQEHIKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWSPKNRSDDATNSDQETDTKCKETDSDDGLKTDCQLDTLSDQDDLAMKSSFPSKLNDV---------------------KPKIWSLA 1126
            +++NS  RRKNATRE+TS LKAWL EH KNPYPTKGEKIMLA+ITKMTLTQVSTWFANARRRLKKENKMTWSP  +S+D  +  ++TD+    +D    L+ D    +L+      +K+ F SKL+ +                     KPKIWS+A
Sbjct:  138 MEMNSHPRRKNATRETTSILKAWLNEHKKNPYPTKGEKIMLAVITKMTLTQVSTWFANARRRLKKENKMTWSPNQKSEDEADDLEDTDS----SDIRSRLQDDPA--SLTKNYSKELKNEFLSKLSAINNLSADISNPKINSNVTSKSTKPKIWSIA 288
[Close]
BLAST of Iroquois-class homeodomain protein IRX-4 vs. Planmine SMEST
Match: SMESG000015279.1 (SMESG000015279.1)

HSP 1 Score: 131.339 bits (329), Expect = 3.305e-33
Identity = 72/121 (59.50%), Postives = 82/121 (67.77%), Query Frame = 2 
Query:  584 SNNHLCCDFGSAWRSAAHMMAADHNPYATYDNSAWANPYGYIGNPTLDLNSARRKNATRESTSTLKAWLQEHIKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWSPKNR 946
            SNN +  D    WR   H    ++N    +   A     GY   P    N+ RRKNATRE+TS LKAWL +H KNPYPTKGEKIMLA+ITKMTLTQVSTWFANARRRLKKENKMTW+ + R
Sbjct:  116 SNNQMLMDHWETWR-QIHQATINNNLSPHF--LALCQSSGY---PPDFPNAPRRKNATRETTSILKAWLNQHKKNPYPTKGEKIMLALITKMTLTQVSTWFANARRRLKKENKMTWTARTR 230
[Close]
BLAST of Iroquois-class homeodomain protein IRX-4 vs. Planmine SMEST
Match: SMESG000022899.1 (SMESG000022899.1)

HSP 1 Score: 117.857 bits (294), Expect = 2.834e-30
Identity = 57/85 (67.06%), Postives = 70/85 (82.35%), Query Frame = 2 
Query:  743 RKNATRESTSTLKAWLQEHIKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWSPKNRSDDATNSDQETDTKCKE 997
            +KNATRE++STLKAWLQEH  NPYP+KGEKI+LAI+T+M+LTQVSTWFANARRRLKKENK+ W    +SD   N D  +D++  E
Sbjct:   95 KKNATRENSSTLKAWLQEHKDNPYPSKGEKILLAILTQMSLTQVSTWFANARRRLKKENKIGWIANGKSD---NPDSTSDSELSE 176
The following BLAST results are available for this feature:
BLAST of Iroquois-class homeodomain protein IRX-4 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
IRX21.718e-3759.54iroquois homeobox 2 [Source:HGNC Symbol;Acc:HGNC:1... [more]
IRX21.718e-3759.54iroquois homeobox 2 [Source:HGNC Symbol;Acc:HGNC:1... [more]
IRX62.304e-3756.82iroquois homeobox 6 [Source:HGNC Symbol;Acc:HGNC:1... [more]
IRX44.127e-3680.46iroquois homeobox 4 [Source:HGNC Symbol;Acc:HGNC:6... [more]
IRX44.127e-3680.46iroquois homeobox 4 [Source:HGNC Symbol;Acc:HGNC:6... [more]
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BLAST of Iroquois-class homeodomain protein IRX-4 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
irx-12.233e-2962.92Putative iroquois-class homeodomain protein irx-1 ... [more]
unc-621.447e-740.74Homeobox protein unc-62 [Source:UniProtKB/Swiss-P... [more]
unc-621.447e-740.74Homeobox protein unc-62 [Source:UniProtKB/Swiss-P... [more]
unc-621.532e-740.74Homeobox protein unc-62 [Source:UniProtKB/Swiss-P... [more]
unc-621.532e-740.74Homeobox protein unc-62 [Source:UniProtKB/Swiss-P... [more]
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BLAST of Iroquois-class homeodomain protein IRX-4 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
caup6.468e-4062.86gene:FBgn0015919 transcript:FBtr0075909[more]
mirr4.833e-3961.07gene:FBgn0014343 transcript:FBtr0075911[more]
mirr4.833e-3961.07gene:FBgn0014343 transcript:FBtr0075912[more]
mirr5.682e-3961.07gene:FBgn0014343 transcript:FBtr0330077[more]
ara4.878e-3777.00gene:FBgn0015904 transcript:FBtr0300551[more]
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BLAST of Iroquois-class homeodomain protein IRX-4 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
irx6a1.666e-4145.85iroquois homeobox 6a [Source:ZFIN;Acc:ZDB-GENE-040... [more]
irx6a1.666e-4145.85iroquois homeobox 6a [Source:ZFIN;Acc:ZDB-GENE-040... [more]
irx4b1.042e-3951.11iroquois homeobox 4b [Source:ZFIN;Acc:ZDB-GENE-040... [more]
irx4b1.042e-3951.11iroquois homeobox 4b [Source:ZFIN;Acc:ZDB-GENE-040... [more]
irx4b1.042e-3951.11iroquois homeobox 4b [Source:ZFIN;Acc:ZDB-GENE-040... [more]
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BLAST of Iroquois-class homeodomain protein IRX-4 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
lypla11.105e-4046.83lysophospholipase 1 [Source:Xenbase;Acc:XB-GENE-94... [more]
fancm1.323e-3758.78FA complementation group M [Source:Xenbase;Acc:XB-... [more]
fancm2.715e-3758.02FA complementation group M [Source:Xenbase;Acc:XB-... [more]
irx41.517e-3681.40iroquois homeobox 4 [Source:NCBI gene;Acc:10003806... [more]
ndufaf51.710e-3667.27NADH:ubiquinone oxidoreductase complex assembly fa... [more]
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BLAST of Iroquois-class homeodomain protein IRX-4 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Irx61.007e-3958.99Iroquois homeobox 6 [Source:MGI Symbol;Acc:MGI:192... [more]
Irx61.061e-3958.99Iroquois homeobox 6 [Source:MGI Symbol;Acc:MGI:192... [more]
Irx25.800e-3877.65Iroquois homeobox 2 [Source:MGI Symbol;Acc:MGI:119... [more]
Irx22.546e-3760.32Iroquois homeobox 2 [Source:MGI Symbol;Acc:MGI:119... [more]
Irx41.528e-3673.47Iroquois homeobox 4 [Source:MGI Symbol;Acc:MGI:135... [more]
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BLAST of Iroquois-class homeodomain protein IRX-4 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|P54269|CAUP_DROME6.483e-3962.86Homeobox protein caupolican OS=Drosophila melanoga... [more]
sp|Q9ER75|IRX6_MOUSE7.423e-3958.99Iroquois-class homeodomain protein IRX-6 OS=Mus mu... [more]
sp|Q66IK1|IRX2_XENTR7.007e-3758.78Iroquois-class homeodomain protein irx-2 OS=Xenopu... [more]
sp|Q9BZI1|IRX2_HUMAN8.250e-3759.54Iroquois-class homeodomain protein IRX-2 OS=Homo s... [more]
sp|P78412|IRX6_HUMAN1.106e-3656.82Iroquois-class homeodomain protein IRX-6 OS=Homo s... [more]
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BLAST of Iroquois-class homeodomain protein IRX-4 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A0A9W3F27.490e-4168.07Homeobox protein araucan OS=Lygus hesperus OX=3008... [more]
A0A5A9PQZ72.708e-4041.39Iroquois-class homeodomain protein IRX-6 Homeodoma... [more]
A0A2T7NIF53.322e-4070.09Homeobox domain-containing protein OS=Pomacea cana... [more]
E9GNW34.137e-4083.72Homeobox domain-containing protein (Fragment) OS=D... [more]
A0A3Q3JHM26.597e-4055.68Iroquois homeobox 6a OS=Monopterus albus OX=43700 ... [more]
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BLAST of Iroquois-class homeodomain protein IRX-4 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
irx4b7.015e-4161.48iroquois-class homeodomain protein irx-4-B [Source... [more]
irx4b1.198e-4061.48iroquois-class homeodomain protein irx-4-B [Source... [more]
irx4a3.910e-3854.78iroquois-class homeodomain protein irx-4 [Source:N... [more]
irx3b9.708e-3877.17iroquois homeobox 3 [Source:NCBI gene;Acc:10303522... [more]
irx5b4.067e-3646.78iroquois homeobox 5b [Source:ZFIN;Acc:ZDB-GENE-040... [more]
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BLAST of Iroquois-class homeodomain protein IRX-4 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 3
Match NameE-valueIdentityDescription
ENSPMAT00000002620.11.304e-3670.30pep scaffold:Pmarinus_7.0:GL484724:8057:10194:-1 g... [more]
mkxb8.017e-1549.28mohawk homeobox b [Source:ZFIN;Acc:ZDB-GENE-080513... [more]
pknox27.832e-1044.44pbx/knotted 1 homeobox 2 [Source:ZFIN;Acc:ZDB-GENE... [more]
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BLAST of Iroquois-class homeodomain protein IRX-4 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 2
Match NameE-valueIdentityDescription
CUP91.037e-1150.00Homeodomain-containing transcriptional repressor; ... [more]
TOS81.480e-1048.21Homeodomain-containing protein and putative transc... [more]
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BLAST of Iroquois-class homeodomain protein IRX-4 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO419822.905e-3792.86Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO393759.971e-1133.33Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO364396.387e-942.86Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO411789.096e-942.86Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO433614.842e-636.21Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Iroquois-class homeodomain protein IRX-4 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
irx6a1.901e-4068.60iroquois homeobox 6 [Source:NCBI gene;Acc:10117320... [more]
irx6a1.923e-4068.60iroquois homeobox 6 [Source:NCBI gene;Acc:10117320... [more]
irx4a7.833e-3956.58iroquois-class homeodomain protein irx-4-like [Sou... [more]
irx3a1.504e-3868.47iroquois homeobox 3 [Source:NCBI gene;Acc:10116211... [more]
irx2a1.652e-3859.85iroquois homeobox 2 [Source:NCBI gene;Acc:10116239... [more]
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BLAST of Iroquois-class homeodomain protein IRX-4 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000061184.10.000e+099.75SMESG000061184.1[more]
SMESG000026100.11.034e-3852.87SMESG000026100.1[more]
SMESG000026100.11.361e-3852.87SMESG000026100.1[more]
SMESG000015279.13.305e-3359.50SMESG000015279.1[more]
SMESG000022899.12.834e-3067.06SMESG000022899.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30018309 ID=SMED30018309|Name=Iroquois-class homeodomain protein IRX-4|organism=Schmidtea mediterranea sexual|type=transcript|length=1503bp
CTGGTGATGTGTCATGTTTTCATAGCTAGCGAATTGGGATGCGATTCCCA
CTTCCTATTTAGCTTGTTAGTCGGGTCAAATATTGTATTTGCTTGTAAAC
CAGGTTGTAAACAAGGAATAACAAATTAGTACAACATAATCATAGTTGAT
AGAACAGTGGTTTGATTAATATTGATAATTGAGGACTCGTTAAAATTTAT
AAGATTCATTAATCTTTTGAAAAATGCATAGCGCTTACTCGAGTCTCATT
AATAGTATTCCTGGACAGATCTCTCTATCCGGAGGAATTCCAGATCAGAT
CAATCCAATATTTAATTATTCAAGTCTCCAAACACAGCAAAATAATGATC
CTTCGTCTCTTCTAAATCTCTACAATCCAGCTTACGCAGCTGCAGCGCAA
TCTAGACTTTTATCATCCTTACATCCGTCGACCTCTCCAAATCATAGCAA
CATCAATTCCACAGATACCAGCACAGTGTCATCGATAACAAGCGCTGAGC
AACCTCCAGCTCCAACATTCGGTCCGGATAGTATTTCTCCGAATACAAAC
ATTCCGTTTTATTCATCGCCTCAAACCTTTACAAGCAACAATCATCTTTG
TTGTGATTTCGGATCTGCGTGGCGATCAGCGGCTCATATGATGGCTGCCG
ATCACAATCCGTACGCTACCTATGATAATTCGGCGTGGGCTAATCCTTAT
GGATACATTGGAAATCCAACTCTCGATTTAAATAGTGCCCGTCGAAAAAA
TGCCACTCGTGAAAGCACTAGTACTCTCAAAGCTTGGCTTCAAGAACACA
TTAAAAACCCCTATCCAACAAAAGGAGAAAAAATCATGTTGGCAATCATA
ACGAAAATGACCTTGACTCAAGTGTCAACTTGGTTTGCTAATGCTCGACG
ACGGTTAAAAAAGGAAAACAAAATGACCTGGTCTCCAAAAAATCGAAGTG
ATGATGCTACTAATTCCGATCAAGAAACCGACACGAAGTGCAAAGAAACT
GATTCCGATGACGGATTGAAAACCGATTGCCAACTTGATACGCTATCTGA
TCAAGATGATTTAGCGATGAAATCTAGTTTCCCATCGAAATTAAATGATG
TAAAACCTAAAATTTGGTCGTTGGCTCACACAGCCACTGCTGGATTATTC
TCAATGCCACTTCAGTCATATCCGGGACATTGTACAGATGGATCAGCTGA
AGACCCTCAAAACAATTCTAACATTAATCAGTATCCAGCCAACATTGGAA
TGCCACTTATATCTAGTCATCCTCTTTATCAACAGGGTTTCTTTCACCAC
ATAGATCTACCGAATCAACTAAACGGTTGTCAGGACAACAAACAATATTC
ACATCTTTATCATCAACAAAATCCAAATAACTTTTTTAATCATTCACAGA
AAAGATCGGAAATGTTGTGATAGACAAACTCGAAAGAGGGGTCTCAATTT
GTACATTGTAATTTTCACCTGCTTTTATTGAAATTAATAAATCTATGATA
TTC
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protein sequence of SMED30018309-orf-1

>SMED30018309-orf-1 ID=SMED30018309-orf-1|Name=SMED30018309-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=399bp
MHSAYSSLINSIPGQISLSGGIPDQINPIFNYSSLQTQQNNDPSSLLNLY
NPAYAAAAQSRLLSSLHPSTSPNHSNINSTDTSTVSSITSAEQPPAPTFG
PDSISPNTNIPFYSSPQTFTSNNHLCCDFGSAWRSAAHMMAADHNPYATY
DNSAWANPYGYIGNPTLDLNSARRKNATRESTSTLKAWLQEHIKNPYPTK
GEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWSPKNRSDDATNSDQ
ETDTKCKETDSDDGLKTDCQLDTLSDQDDLAMKSSFPSKLNDVKPKIWSL
AHTATAGLFSMPLQSYPGHCTDGSAEDPQNNSNINQYPANIGMPLISSHP
LYQQGFFHHIDLPNQLNGCQDNKQYSHLYHQQNPNNFFNHSQKRSEML*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000099neuron
PLANA:0000101muscle cell
PLANA:0000142posterior region of the whole animal
PLANA:0000418head
Vocabulary: INTERPRO
TermDefinition
IPR003893Iroquois_homeo
IPR001356Homeobox_dom
IPR008422Homeobox_KN_domain
IPR009057Homeobox-like_sf
IPR017970Homeobox_CS
Vocabulary: biological process
TermDefinition
GO:0006355regulation of transcription, DNA-templated
Vocabulary: molecular function
TermDefinition
GO:0003677DNA binding
GO:0043565sequence-specific DNA binding
Vocabulary: cellular component
TermDefinition
GO:0005634nucleus
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR003893Iroquois-class homeodomain proteinSMARTSM00548irx_3coord: 290..307
e-value: 0.0047
score: 26.2
IPR001356Homeobox domainSMARTSM00389HOX_1coord: 170..235
e-value: 3.9E-11
score: 53.0
IPR001356Homeobox domainPROSITEPS50071HOMEOBOX_2coord: 168..231
score: 13.297
IPR001356Homeobox domainCDDcd00086homeodomaincoord: 173..232
e-value: 2.91629E-14
score: 64.9572
NoneNo IPR availableGENE3DG3DSA:1.10.10.60coord: 170..231
e-value: 1.2E-25
score: 91.1
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 67..103
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 232..263
NoneNo IPR availablePANTHERPTHR11211IROQUOIS-CLASS HOMEODOMAIN PROTEIN IRXcoord: 36..279
IPR008422Homeobox KN domainPFAMPF05920Homeobox_KNcoord: 188..227
e-value: 1.5E-15
score: 56.8
IPR017970Homeobox, conserved sitePROSITEPS00027HOMEOBOX_1coord: 206..229
IPR009057Homeobox-like domain superfamilySUPERFAMILYSSF46689Homeodomain-likecoord: 173..238