Small conductance calcium-activated potassium channel protein 2

Overview
NameSmall conductance calcium-activated potassium channel protein 2
Smed IDSMED30018278
Length (bp)1463
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Small conductance calcium-activated potassium channel protein 2 (SMED30018278) t-SNE clustered cells

Violin plots show distribution of expression levels for Small conductance calcium-activated potassium channel protein 2 (SMED30018278) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Small conductance calcium-activated potassium channel protein 2 (SMED30018278) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Small conductance calcium-activated potassium channel protein 2 (SMED30018278) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30018278

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 4

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
cephalic gangliaSMED30018278h1SMcG0011985 dd_Smed_v4_12169_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parapharyngeal regionSMED30018278h1SMcG0011985 dd_Smed_v4_12169_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30018278h1SMcG0011985 Contig47933newmark_estsPMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30018278h1SMcG0011985 Contig47933uc_Smed_v2PMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of Small conductance calcium-activated potassium channel protein 2 vs. Ensembl Human
Match: KCNN1 (potassium calcium-activated channel subfamily N member 1 [Source:HGNC Symbol;Acc:HGNC:6290])

HSP 1 Score: 212.616 bits (540), Expect = 6.418e-62
Identity = 120/322 (37.27%), Postives = 188/322 (58.39%), Query Frame = 1
Query:  235 SVGSTMSTRKCLHNNQKILSIFCLIFAAVGIGLMIIEIEIVSYNASNQISQLCFVCFFLKVLVSFFTGLLLICLVFYHRASILLFMVENNLNSWRFVITVRLSLSIFIELAICAIHAPPIP-NYNYVWTTYRLILGRPEKEDVPLDVIITIIMFLRGYLIFRVMVLHSHVYDNSSSRCVELMQGKSINSQFALKYLLTIYSKAFLIVSVICVILWTSWAVRVCEIYEKDSNL--RFFNNIWFIAITFMTIGYGDIVPRSVCGRFIAVLSGVFGVMYTAYVVAIIAXXXXXXXXXXXXHQFVVDSDLDKSIKEQAVIIIQNFW 1191
            +VG  +  R+ L   +K LS + LIF   GI +M+ E E+ S+    + S      F LK L+S  T +LL  +V YH   I LFMV+N  + WR  +T      I +ELA+CAIH  P+P +Y + WT        P   +  +DV+++I MFLR YL+ RVM+LHS ++ ++SSR +  +   + N++F +K L+TI     L+V  I   +  +W VRVCE Y     +   F   +W I+ITF++IGYGD+VP + CG+ + +L+G+ G   TA VVA++A  L+L+ +E ++H F++D+ L K +K  A  +++  W
Sbjct:   88 NVGHRLGHRRALFEKRKRLSDYALIFGMFGIVVMVTETEL-SWGVYTKES---LYSFALKCLISLSTAILLGLVVLYHAREIQLFMVDNGADDWRIAMTCERVFLISLELAVCAIH--PVPGHYRFTWTARLAFTYAPSVAEADVDVLLSIPMFLRLYLLGRVMLLHSKIFTDASSRSIGALNKITFNTRFVMKTLMTICPGTVLLVFSISSWIIAAWTVRVCERYHDKQEVTSNFLGAMWLISITFLSIGYGDMVPHTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTKRVKNAAANVLRETW 403          
BLAST of Small conductance calcium-activated potassium channel protein 2 vs. Ensembl Human
Match: KCNN1 (potassium calcium-activated channel subfamily N member 1 [Source:HGNC Symbol;Acc:HGNC:6290])

HSP 1 Score: 212.616 bits (540), Expect = 7.348e-62
Identity = 120/322 (37.27%), Postives = 188/322 (58.39%), Query Frame = 1
Query:  235 SVGSTMSTRKCLHNNQKILSIFCLIFAAVGIGLMIIEIEIVSYNASNQISQLCFVCFFLKVLVSFFTGLLLICLVFYHRASILLFMVENNLNSWRFVITVRLSLSIFIELAICAIHAPPIP-NYNYVWTTYRLILGRPEKEDVPLDVIITIIMFLRGYLIFRVMVLHSHVYDNSSSRCVELMQGKSINSQFALKYLLTIYSKAFLIVSVICVILWTSWAVRVCEIYEKDSNL--RFFNNIWFIAITFMTIGYGDIVPRSVCGRFIAVLSGVFGVMYTAYVVAIIAXXXXXXXXXXXXHQFVVDSDLDKSIKEQAVIIIQNFW 1191
            +VG  +  R+ L   +K LS + LIF   GI +M+ E E+ S+    + S      F LK L+S  T +LL  +V YH   I LFMV+N  + WR  +T      I +ELA+CAIH  P+P +Y + WT        P   +  +DV+++I MFLR YL+ RVM+LHS ++ ++SSR +  +   + N++F +K L+TI     L+V  I   +  +W VRVCE Y     +   F   +W I+ITF++IGYGD+VP + CG+ + +L+G+ G   TA VVA++A  L+L+ +E ++H F++D+ L K +K  A  +++  W
Sbjct:   88 NVGHRLGHRRALFEKRKRLSDYALIFGMFGIVVMVTETEL-SWGVYTKES---LYSFALKCLISLSTAILLGLVVLYHAREIQLFMVDNGADDWRIAMTCERVFLISLELAVCAIH--PVPGHYRFTWTARLAFTYAPSVAEADVDVLLSIPMFLRLYLLGRVMLLHSKIFTDASSRSIGALNKITFNTRFVMKTLMTICPGTVLLVFSISSWIIAAWTVRVCERYHDKQEVTSNFLGAMWLISITFLSIGYGDMVPHTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTKRVKNAAANVLRETW 403          
BLAST of Small conductance calcium-activated potassium channel protein 2 vs. Ensembl Human
Match: KCNN2 (potassium calcium-activated channel subfamily N member 2 [Source:HGNC Symbol;Acc:HGNC:6291])

HSP 1 Score: 210.69 bits (535), Expect = 6.326e-61
Identity = 121/330 (36.67%), Postives = 194/330 (58.79%), Query Frame = 1
Query:  232 KSVGSTMSTRKCLHNNQKILSIFCLIFAAVGIGLMIIEIEIVSYNASNQISQLCFVCFFLKVLVSFFTGLLLICLVFYHRASILLFMVENNLNSWRFVITVRLSLSIFIELAICAIHAPPIP-NYNYVWTTYRLILGRPEKEDVPLDVIITIIMFLRGYLIFRVMVLHSHVYDNSSSRCVELMQGKSINSQFALKYLLTIYSKAFLIVSVICVILWTSWAVRVCEIY--EKDSNLRFFNNIWFIAITFMTIGYGDIVPRSVCGRFIAVLSGVFGVMYTAYVVAIIAXXXXXXXXXXXXHQFVVDSDLDKSIKEQAVIIIQNFWRLKRAIK 1212
            +++G  +  R+ L   +K LS + LIF   GI +M+IE E+ S+ A ++ S        LK L+S  T +LL  ++ YH   I LFMV+N  + WR  +T      I +E+ +CAIH  PIP NY + WT        P      +D+I++I MFLR YLI RVM+LHS ++ ++SSR +  +   + N++F +K L+TI     L+V  I + +  +W VR CE Y  ++D    F   +W I+ITF++IGYGD+VP + CG+ + +L+G+ G   TA VVA++A  L+L+ +E ++H F++D+ L K +K  A  +++  W + +  K
Sbjct:  115 QNIGYKLGHRRALFEKRKRLSDYALIFGMFGIVVMVIETEL-SWGAYDKAS---LYSLALKCLISLSTIILLGLIIVYHAREIQLFMVDNGADDWRIAMTYERIFFICLEILVCAIH--PIPGNYTFTWTARLAFSYAPSTTTADVDIILSIPMFLRLYLIARVMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFSISLWIIAAWTVRACERYHDQQDVTSNFLGAMWLISITFLSIGYGDMVPNTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTKRVKNAAANVLRETWLIYKNTK 438          
BLAST of Small conductance calcium-activated potassium channel protein 2 vs. Ensembl Human
Match: KCNN2 (potassium calcium-activated channel subfamily N member 2 [Source:HGNC Symbol;Acc:HGNC:6291])

HSP 1 Score: 210.69 bits (535), Expect = 8.829e-61
Identity = 120/323 (37.15%), Postives = 191/323 (59.13%), Query Frame = 1
Query:  232 KSVGSTMSTRKCLHNNQKILSIFCLIFAAVGIGLMIIEIEIVSYNASNQISQLCFVCFFLKVLVSFFTGLLLICLVFYHRASILLFMVENNLNSWRFVITVRLSLSIFIELAICAIHAPPIP-NYNYVWTTYRLILGRPEKEDVPLDVIITIIMFLRGYLIFRVMVLHSHVYDNSSSRCVELMQGKSINSQFALKYLLTIYSKAFLIVSVICVILWTSWAVRVCEIY--EKDSNLRFFNNIWFIAITFMTIGYGDIVPRSVCGRFIAVLSGVFGVMYTAYVVAIIAXXXXXXXXXXXXHQFVVDSDLDKSIKEQAVIIIQNFW 1191
            +++G  +  R+ L   +K LS + LIF   GI +M+IE E+ S+ A ++ S        LK L+S  T +LL  ++ YH   I LFMV+N  + WR  +T      I +E+ +CAIH  PIP NY + WT        P      +D+I++I MFLR YLI RVM+LHS ++ ++SSR +  +   + N++F +K L+TI     L+V  I + +  +W VR CE Y  ++D    F   +W I+ITF++IGYGD+VP + CG+ + +L+G+ G   TA VVA++A  L+L+ +E ++H F++D+ L K +K  A  +++  W
Sbjct:  128 QNIGYKLGHRRALFEKRKRLSDYALIFGMFGIVVMVIETEL-SWGAYDKAS---LYSLALKCLISLSTIILLGLIIVYHAREIQLFMVDNGADDWRIAMTYERIFFICLEILVCAIH--PIPGNYTFTWTARLAFSYAPSTTTADVDIILSIPMFLRLYLIARVMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFSISLWIIAAWTVRACERYHDQQDVTSNFLGAMWLISITFLSIGYGDMVPNTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTKRVKNAAANVLRETW 444          
BLAST of Small conductance calcium-activated potassium channel protein 2 vs. Ensembl Human
Match: KCNN2 (potassium calcium-activated channel subfamily N member 2 [Source:HGNC Symbol;Acc:HGNC:6291])

HSP 1 Score: 209.92 bits (533), Expect = 3.272e-59
Identity = 120/323 (37.15%), Postives = 191/323 (59.13%), Query Frame = 1
Query:  232 KSVGSTMSTRKCLHNNQKILSIFCLIFAAVGIGLMIIEIEIVSYNASNQISQLCFVCFFLKVLVSFFTGLLLICLVFYHRASILLFMVENNLNSWRFVITVRLSLSIFIELAICAIHAPPIP-NYNYVWTTYRLILGRPEKEDVPLDVIITIIMFLRGYLIFRVMVLHSHVYDNSSSRCVELMQGKSINSQFALKYLLTIYSKAFLIVSVICVILWTSWAVRVCEIY--EKDSNLRFFNNIWFIAITFMTIGYGDIVPRSVCGRFIAVLSGVFGVMYTAYVVAIIAXXXXXXXXXXXXHQFVVDSDLDKSIKEQAVIIIQNFW 1191
            +++G  +  R+ L   +K LS + LIF   GI +M+IE E+ S+ A ++ S        LK L+S  T +LL  ++ YH   I LFMV+N  + WR  +T      I +E+ +CAIH  PIP NY + WT        P      +D+I++I MFLR YLI RVM+LHS ++ ++SSR +  +   + N++F +K L+TI     L+V  I + +  +W VR CE Y  ++D    F   +W I+ITF++IGYGD+VP + CG+ + +L+G+ G   TA VVA++A  L+L+ +E ++H F++D+ L K +K  A  +++  W
Sbjct:  327 QNIGYKLGHRRALFEKRKRLSDYALIFGMFGIVVMVIETEL-SWGAYDKAS---LYSLALKCLISLSTIILLGLIIVYHAREIQLFMVDNGADDWRIAMTYERIFFICLEILVCAIH--PIPGNYTFTWTARLAFSYAPSTTTADVDIILSIPMFLRLYLIARVMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFSISLWIIAAWTVRACERYHDQQDVTSNFLGAMWLISITFLSIGYGDMVPNTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTKRVKNAAANVLRETW 643          
BLAST of Small conductance calcium-activated potassium channel protein 2 vs. Ensembl Celegans
Match: kcnl-2 (KCNN (Potassium K ChaNNel, calcium activated)-Like [Source:UniProtKB/TrEMBL;Acc:G5EDA9])

HSP 1 Score: 163.31 bits (412), Expect = 1.296e-43
Identity = 109/327 (33.33%), Postives = 181/327 (55.35%), Query Frame = 1
Query:  241 GSTMSTRKCLHNNQKILSIFCLIFAAVGIGLMIIEIEIVSYNASNQISQLCFVCFFLKVLVSFFTGLLLICLVFYHRASILLFMVENNLNSWRFVITVRLSLSIFIELAICAIHAPPI----PNYNYVWTTYRLILGRPEKEDVPLDVIITIIMFLRGYLIFRVMVLHSHVYDNSSSRCVELMQGKSINSQFALKYLLTIYSKAFLIVSVICVILW--TSWAVRVCE----IYEKDSNLRFFNNIWFIAITFMTIGYGDIVPRSVCGRFIAVLSGVFGVMYTAYVVAIIAXXXXXXXXXXXXHQFVVDSDLDKSIKEQAVIIIQNFW 1191
            G  +  R+ LH  ++ +S   L FA +GI LMIIE E+ +       S L  +   LK  + F T  LL  + ++H   I LFM  N  + W   ++ R +  I +EL IC +   PI    P  N  +          +K    ++V ++I+MF R Y + RVM+LHS V+ ++SSR +  +   + N++F LK L+TI     L++      LW    W +R+CE      +K +++ + N+IW +AITF+++GYGDIVP++ CGR +A+++G+ G   ++ VVA+IA  L+L+ +E ++H F+ D+ L K +K  A  +++  W
Sbjct:  201 GGRLIRREILHEKRRHVSDRALAFAIMGIILMIIENELRTAYVIRPGSSLSHL---LKFFIIFTTTALLSFVGYFHVIEIQLFMNANAADDWMVALSFRRTCQIGLELLICMLCPLPIEFIAPFMNDRFH---------DKTLYAVNVFLSIMMFFRLYWLCRVMLLHSRVFTDASSRSIAGLNRVNFNARFILKTLMTICPGTMLMI--FTAFLWIIAGWILRLCEREYMTPDKYNDINYVNSIWLVAITFLSVGYGDIVPKTNCGRSMAIVTGILGTCASSMVVAVIARKLELTRAEKHVHNFMQDTQLTKQLKHSAANVLRETW 513          
BLAST of Small conductance calcium-activated potassium channel protein 2 vs. Ensembl Celegans
Match: kcnl-2 (KCNN (Potassium K ChaNNel, calcium activated)-Like [Source:UniProtKB/TrEMBL;Acc:G5EDA9])

HSP 1 Score: 163.31 bits (412), Expect = 1.683e-43
Identity = 109/327 (33.33%), Postives = 181/327 (55.35%), Query Frame = 1
Query:  241 GSTMSTRKCLHNNQKILSIFCLIFAAVGIGLMIIEIEIVSYNASNQISQLCFVCFFLKVLVSFFTGLLLICLVFYHRASILLFMVENNLNSWRFVITVRLSLSIFIELAICAIHAPPI----PNYNYVWTTYRLILGRPEKEDVPLDVIITIIMFLRGYLIFRVMVLHSHVYDNSSSRCVELMQGKSINSQFALKYLLTIYSKAFLIVSVICVILW--TSWAVRVCE----IYEKDSNLRFFNNIWFIAITFMTIGYGDIVPRSVCGRFIAVLSGVFGVMYTAYVVAIIAXXXXXXXXXXXXHQFVVDSDLDKSIKEQAVIIIQNFW 1191
            G  +  R+ LH  ++ +S   L FA +GI LMIIE E+ +       S L  +   LK  + F T  LL  + ++H   I LFM  N  + W   ++ R +  I +EL IC +   PI    P  N  +          +K    ++V ++I+MF R Y + RVM+LHS V+ ++SSR +  +   + N++F LK L+TI     L++      LW    W +R+CE      +K +++ + N+IW +AITF+++GYGDIVP++ CGR +A+++G+ G   ++ VVA+IA  L+L+ +E ++H F+ D+ L K +K  A  +++  W
Sbjct:  228 GGRLIRREILHEKRRHVSDRALAFAIMGIILMIIENELRTAYVIRPGSSLSHL---LKFFIIFTTTALLSFVGYFHVIEIQLFMNANAADDWMVALSFRRTCQIGLELLICMLCPLPIEFIAPFMNDRFH---------DKTLYAVNVFLSIMMFFRLYWLCRVMLLHSRVFTDASSRSIAGLNRVNFNARFILKTLMTICPGTMLMI--FTAFLWIIAGWILRLCEREYMTPDKYNDINYVNSIWLVAITFLSVGYGDIVPKTNCGRSMAIVTGILGTCASSMVVAVIARKLELTRAEKHVHNFMQDTQLTKQLKHSAANVLRETW 540          
BLAST of Small conductance calcium-activated potassium channel protein 2 vs. Ensembl Celegans
Match: kcnl-2 (KCNN (Potassium K ChaNNel, calcium activated)-Like [Source:UniProtKB/TrEMBL;Acc:G5EDA9])

HSP 1 Score: 163.31 bits (412), Expect = 1.731e-43
Identity = 109/327 (33.33%), Postives = 181/327 (55.35%), Query Frame = 1
Query:  241 GSTMSTRKCLHNNQKILSIFCLIFAAVGIGLMIIEIEIVSYNASNQISQLCFVCFFLKVLVSFFTGLLLICLVFYHRASILLFMVENNLNSWRFVITVRLSLSIFIELAICAIHAPPI----PNYNYVWTTYRLILGRPEKEDVPLDVIITIIMFLRGYLIFRVMVLHSHVYDNSSSRCVELMQGKSINSQFALKYLLTIYSKAFLIVSVICVILW--TSWAVRVCE----IYEKDSNLRFFNNIWFIAITFMTIGYGDIVPRSVCGRFIAVLSGVFGVMYTAYVVAIIAXXXXXXXXXXXXHQFVVDSDLDKSIKEQAVIIIQNFW 1191
            G  +  R+ LH  ++ +S   L FA +GI LMIIE E+ +       S L  +   LK  + F T  LL  + ++H   I LFM  N  + W   ++ R +  I +EL IC +   PI    P  N  +          +K    ++V ++I+MF R Y + RVM+LHS V+ ++SSR +  +   + N++F LK L+TI     L++      LW    W +R+CE      +K +++ + N+IW +AITF+++GYGDIVP++ CGR +A+++G+ G   ++ VVA+IA  L+L+ +E ++H F+ D+ L K +K  A  +++  W
Sbjct:  228 GGRLIRREILHEKRRHVSDRALAFAIMGIILMIIENELRTAYVIRPGSSLSHL---LKFFIIFTTTALLSFVGYFHVIEIQLFMNANAADDWMVALSFRRTCQIGLELLICMLCPLPIEFIAPFMNDRFH---------DKTLYAVNVFLSIMMFFRLYWLCRVMLLHSRVFTDASSRSIAGLNRVNFNARFILKTLMTICPGTMLMI--FTAFLWIIAGWILRLCEREYMTPDKYNDINYVNSIWLVAITFLSVGYGDIVPKTNCGRSMAIVTGILGTCASSMVVAVIARKLELTRAEKHVHNFMQDTQLTKQLKHSAANVLRETW 540          
BLAST of Small conductance calcium-activated potassium channel protein 2 vs. Ensembl Celegans
Match: kcnl-2 (KCNN (Potassium K ChaNNel, calcium activated)-Like [Source:UniProtKB/TrEMBL;Acc:G5EDA9])

HSP 1 Score: 162.925 bits (411), Expect = 1.767e-43
Identity = 109/327 (33.33%), Postives = 181/327 (55.35%), Query Frame = 1
Query:  241 GSTMSTRKCLHNNQKILSIFCLIFAAVGIGLMIIEIEIVSYNASNQISQLCFVCFFLKVLVSFFTGLLLICLVFYHRASILLFMVENNLNSWRFVITVRLSLSIFIELAICAIHAPPI----PNYNYVWTTYRLILGRPEKEDVPLDVIITIIMFLRGYLIFRVMVLHSHVYDNSSSRCVELMQGKSINSQFALKYLLTIYSKAFLIVSVICVILW--TSWAVRVCE----IYEKDSNLRFFNNIWFIAITFMTIGYGDIVPRSVCGRFIAVLSGVFGVMYTAYVVAIIAXXXXXXXXXXXXHQFVVDSDLDKSIKEQAVIIIQNFW 1191
            G  +  R+ LH  ++ +S   L FA +GI LMIIE E+ +       S L  +   LK  + F T  LL  + ++H   I LFM  N  + W   ++ R +  I +EL IC +   PI    P  N  +          +K    ++V ++I+MF R Y + RVM+LHS V+ ++SSR +  +   + N++F LK L+TI     L++      LW    W +R+CE      +K +++ + N+IW +AITF+++GYGDIVP++ CGR +A+++G+ G   ++ VVA+IA  L+L+ +E ++H F+ D+ L K +K  A  +++  W
Sbjct:  208 GGRLIRREILHEKRRHVSDRALAFAIMGIILMIIENELRTAYVIRPGSSLSHL---LKFFIIFTTTALLSFVGYFHVIEIQLFMNANAADDWMVALSFRRTCQIGLELLICMLCPLPIEFIAPFMNDRFH---------DKTLYAVNVFLSIMMFFRLYWLCRVMLLHSRVFTDASSRSIAGLNRVNFNARFILKTLMTICPGTMLMI--FTAFLWIIAGWILRLCEREYMTPDKYNDINYVNSIWLVAITFLSVGYGDIVPKTNCGRSMAIVTGILGTCASSMVVAVIARKLELTRAEKHVHNFMQDTQLTKQLKHSAANVLRETW 520          
BLAST of Small conductance calcium-activated potassium channel protein 2 vs. Ensembl Celegans
Match: kcnl-2 (KCNN (Potassium K ChaNNel, calcium activated)-Like [Source:UniProtKB/TrEMBL;Acc:G5EDA9])

HSP 1 Score: 162.54 bits (410), Expect = 2.028e-43
Identity = 109/327 (33.33%), Postives = 181/327 (55.35%), Query Frame = 1
Query:  241 GSTMSTRKCLHNNQKILSIFCLIFAAVGIGLMIIEIEIVSYNASNQISQLCFVCFFLKVLVSFFTGLLLICLVFYHRASILLFMVENNLNSWRFVITVRLSLSIFIELAICAIHAPPI----PNYNYVWTTYRLILGRPEKEDVPLDVIITIIMFLRGYLIFRVMVLHSHVYDNSSSRCVELMQGKSINSQFALKYLLTIYSKAFLIVSVICVILW--TSWAVRVCE----IYEKDSNLRFFNNIWFIAITFMTIGYGDIVPRSVCGRFIAVLSGVFGVMYTAYVVAIIAXXXXXXXXXXXXHQFVVDSDLDKSIKEQAVIIIQNFW 1191
            G  +  R+ LH  ++ +S   L FA +GI LMIIE E+ +       S L  +   LK  + F T  LL  + ++H   I LFM  N  + W   ++ R +  I +EL IC +   PI    P  N  +          +K    ++V ++I+MF R Y + RVM+LHS V+ ++SSR +  +   + N++F LK L+TI     L++      LW    W +R+CE      +K +++ + N+IW +AITF+++GYGDIVP++ CGR +A+++G+ G   ++ VVA+IA  L+L+ +E ++H F+ D+ L K +K  A  +++  W
Sbjct:  208 GGRLIRREILHEKRRHVSDRALAFAIMGIILMIIENELRTAYVIRPGSSLSHL---LKFFIIFTTTALLSFVGYFHVIEIQLFMNANAADDWMVALSFRRTCQIGLELLICMLCPLPIEFIAPFMNDRFH---------DKTLYAVNVFLSIMMFFRLYWLCRVMLLHSRVFTDASSRSIAGLNRVNFNARFILKTLMTICPGTMLMI--FTAFLWIIAGWILRLCEREYMTPDKYNDINYVNSIWLVAITFLSVGYGDIVPKTNCGRSMAIVTGILGTCASSMVVAVIARKLELTRAEKHVHNFMQDTQLTKQLKHSAANVLRETW 520          
BLAST of Small conductance calcium-activated potassium channel protein 2 vs. Ensembl Fly
Match: SK (gene:FBgn0029761 transcript:FBtr0300467)

HSP 1 Score: 202.216 bits (513), Expect = 1.622e-58
Identity = 122/328 (37.20%), Postives = 191/328 (58.23%), Query Frame = 1
Query:  229 RKSVGSTMSTRKCLHNNQKILSIFCLIFAAVGIGLMIIEIEIVSYNASNQISQLCFVCFFLKVLVSFFTGLLLICLVFYH--RASILLFMVENNLNSWRFVITVRLSLSIFIELAICAIHAPPIPN-YNYVWTTYRLILGRPEK----EDVPLDVIITIIMFLRGYLIFRVMVLHSHVYDNSSSRCVELMQGKSINSQFALKYLLTIYSKAFLIVSVICVILWTSWAVRVCEIYEKDSNLRFFNNIWFIAITFMTIGYGDIVPRSVCGRFIAVLSGVFGVMYTAYVVAIIAXXXXXXXXXXXXHQFVVDSDLDKSIKEQAVIIIQNFW 1191
            + +VG  +  RK L   +K +S + L+    GI +M+IE E+ S     + S   F    LK L+S  T +LL  +V YH     + LFM++N  + WR  +T +    I +EL ICAIH  PIP  Y + WTT    L    K    E VP DV +++ MFLR YLI RVM+LHS ++ ++SSR +  +   + N++F LK L+TI     L+V ++ + +  SW +R CE +  + +    N +W IAITF+++G+GDIVP + CGR IAV +G+ G   TA +VA+++  L+L+ +E ++H F++D+ L K +K  A  +++  W
Sbjct:   60 KPNVGYRLGKRKALFEKRKRISDYALVMGMFGIIVMVIENELSSAGVYTKAS---FYSTALKTLISVSTVILLGLIVAYHALEVQVRLFMIDNCADDWRIAMTWQRISQIGLELFICAIH--PIPGEYYFQWTTK---LANKNKTIGTEMVPYDVALSLPMFLRLYLICRVMLLHSKLFTDASSRSIGALNRINFNTRFVLKTLMTICPGTVLLVFMVSLWIIASWTLRQCERFHDEEHANLLNAMWLIAITFLSVGFGDIVPNTYCGRGIAVSTGIMGAGCTALLVAVVSRKLELTRAEKHVHNFMMDTQLTKRLKNAAANVLRETW 379          
BLAST of Small conductance calcium-activated potassium channel protein 2 vs. Ensembl Fly
Match: SK (gene:FBgn0029761 transcript:FBtr0301949)

HSP 1 Score: 200.675 bits (509), Expect = 5.464e-58
Identity = 120/326 (36.81%), Postives = 188/326 (57.67%), Query Frame = 1
Query:  229 RKSVGSTMSTRKCLHNNQKILSIFCLIFAAVGIGLMIIEIEIVSYNASNQISQLCFVCFFLKVLVSFFTGLLLICLVFYHRASILLFMVENNLNSWRFVITVRLSLSIFIELAICAIHAPPIPN-YNYVWTTYRLILGRPEK----EDVPLDVIITIIMFLRGYLIFRVMVLHSHVYDNSSSRCVELMQGKSINSQFALKYLLTIYSKAFLIVSVICVILWTSWAVRVCEIYEKDSNLRFFNNIWFIAITFMTIGYGDIVPRSVCGRFIAVLSGVFGVMYTAYVVAIIAXXXXXXXXXXXXHQFVVDSDLDKSIKEQAVIIIQNFW 1191
            + +VG  +  RK L   +K +S + L+    GI +M+IE E+ S     + S   F    LK L+S  T +LL  +V YH   + LFM++N  + WR  +T +    I +EL ICAIH  PIP  Y + WTT    L    K    E VP DV +++ MFLR YLI RVM+LHS ++ ++SSR +  +   + N++F LK L+TI     L+V ++ + +  SW +R CE +  + +    N++W  AITF+ +GYGDIVP + CGR I +  G+ G   TA +VA+++  L+L+ +E ++H F++D+ L K +K  A  +++  W
Sbjct:   60 KPNVGYRLGKRKALFEKRKRISDYALVMGMFGIIVMVIENELSSAGVYTKAS---FYSTALKTLISVSTVILLGLIVAYHALEVQLFMIDNCADDWRIAMTWQRISQIGLELFICAIH--PIPGEYYFQWTTK---LANKNKTIGTEMVPYDVALSLPMFLRLYLICRVMLLHSKLFTDASSRSIGALNRINFNTRFVLKTLMTICPGTVLLVFMVSLWIIASWTLRQCERFHDEEHANLLNSMWLTAITFLCVGYGDIVPNTYCGRGITLTCGMVGAGCTALLVAVVSRKLELTRAEKHVHNFMMDTQLTKRLKNAAANVLRETW 377          
BLAST of Small conductance calcium-activated potassium channel protein 2 vs. Ensembl Fly
Match: SK (gene:FBgn0029761 transcript:FBtr0301952)

HSP 1 Score: 199.904 bits (507), Expect = 3.563e-57
Identity = 120/326 (36.81%), Postives = 188/326 (57.67%), Query Frame = 1
Query:  229 RKSVGSTMSTRKCLHNNQKILSIFCLIFAAVGIGLMIIEIEIVSYNASNQISQLCFVCFFLKVLVSFFTGLLLICLVFYHRASILLFMVENNLNSWRFVITVRLSLSIFIELAICAIHAPPIPN-YNYVWTTYRLILGRPEK----EDVPLDVIITIIMFLRGYLIFRVMVLHSHVYDNSSSRCVELMQGKSINSQFALKYLLTIYSKAFLIVSVICVILWTSWAVRVCEIYEKDSNLRFFNNIWFIAITFMTIGYGDIVPRSVCGRFIAVLSGVFGVMYTAYVVAIIAXXXXXXXXXXXXHQFVVDSDLDKSIKEQAVIIIQNFW 1191
            + +VG  +  RK L   +K +S + L+    GI +M+IE E+ S     + S   F    LK L+S  T +LL  +V YH   + LFM++N  + WR  +T +    I +EL ICAIH  PIP  Y + WTT    L    K    E VP DV +++ MFLR YLI RVM+LHS ++ ++SSR +  +   + N++F LK L+TI     L+V ++ + +  SW +R CE +  + +    N++W  AITF+ +GYGDIVP + CGR I +  G+ G   TA +VA+++  L+L+ +E ++H F++D+ L K +K  A  +++  W
Sbjct:   60 KPNVGYRLGKRKALFEKRKRISDYALVMGMFGIIVMVIENELSSAGVYTKAS---FYSTALKTLISVSTVILLGLIVAYHALEVQLFMIDNCADDWRIAMTWQRISQIGLELFICAIH--PIPGEYYFQWTTK---LANKNKTIGTEMVPYDVALSLPMFLRLYLICRVMLLHSKLFTDASSRSIGALNRINFNTRFVLKTLMTICPGTVLLVFMVSLWIIASWTLRQCERFHDEEHANLLNSMWLTAITFLCVGYGDIVPNTYCGRGITLTCGMVGAGCTALLVAVVSRKLELTRAEKHVHNFMMDTQLTKRLKNAAANVLRETW 377          
BLAST of Small conductance calcium-activated potassium channel protein 2 vs. Ensembl Fly
Match: SK (gene:FBgn0029761 transcript:FBtr0301953)

HSP 1 Score: 204.142 bits (518), Expect = 6.212e-57
Identity = 122/326 (37.42%), Postives = 191/326 (58.59%), Query Frame = 1
Query:  229 RKSVGSTMSTRKCLHNNQKILSIFCLIFAAVGIGLMIIEIEIVSYNASNQISQLCFVCFFLKVLVSFFTGLLLICLVFYHRASILLFMVENNLNSWRFVITVRLSLSIFIELAICAIHAPPIPN-YNYVWTTYRLILGRPEK----EDVPLDVIITIIMFLRGYLIFRVMVLHSHVYDNSSSRCVELMQGKSINSQFALKYLLTIYSKAFLIVSVICVILWTSWAVRVCEIYEKDSNLRFFNNIWFIAITFMTIGYGDIVPRSVCGRFIAVLSGVFGVMYTAYVVAIIAXXXXXXXXXXXXHQFVVDSDLDKSIKEQAVIIIQNFW 1191
            + +VG  +  RK L   +K +S + L+    GI +M+IE E+ S     + S   F    LK L+S  T +LL  +V YH   + LFM++N  + WR  +T +    I +EL ICAIH  PIP  Y + WTT    L    K    E VP DV +++ MFLR YLI RVM+LHS ++ ++SSR +  +   + N++F LK L+TI     L+V ++ + +  SW +R CE +  + +    N +W IAITF+++G+GDIVP + CGR IAV +G+ G   TA +VA+++  L+L+ +E ++H F++D+ L K +K  A  +++  W
Sbjct:  465 KPNVGYRLGKRKALFEKRKRISDYALVMGMFGIIVMVIENELSSAGVYTKAS---FYSTALKTLISVSTVILLGLIVAYHALEVQLFMIDNCADDWRIAMTWQRISQIGLELFICAIH--PIPGEYYFQWTTK---LANKNKTIGTEMVPYDVALSLPMFLRLYLICRVMLLHSKLFTDASSRSIGALNRINFNTRFVLKTLMTICPGTVLLVFMVSLWIIASWTLRQCERFHDEEHANLLNAMWLIAITFLSVGFGDIVPNTYCGRGIAVSTGIMGAGCTALLVAVVSRKLELTRAEKHVHNFMMDTQLTKRLKNAAANVLRETW 782          
BLAST of Small conductance calcium-activated potassium channel protein 2 vs. Ensembl Fly
Match: SK (gene:FBgn0029761 transcript:FBtr0301954)

HSP 1 Score: 200.675 bits (509), Expect = 8.763e-57
Identity = 120/326 (36.81%), Postives = 188/326 (57.67%), Query Frame = 1
Query:  229 RKSVGSTMSTRKCLHNNQKILSIFCLIFAAVGIGLMIIEIEIVSYNASNQISQLCFVCFFLKVLVSFFTGLLLICLVFYHRASILLFMVENNLNSWRFVITVRLSLSIFIELAICAIHAPPIPN-YNYVWTTYRLILGRPEK----EDVPLDVIITIIMFLRGYLIFRVMVLHSHVYDNSSSRCVELMQGKSINSQFALKYLLTIYSKAFLIVSVICVILWTSWAVRVCEIYEKDSNLRFFNNIWFIAITFMTIGYGDIVPRSVCGRFIAVLSGVFGVMYTAYVVAIIAXXXXXXXXXXXXHQFVVDSDLDKSIKEQAVIIIQNFW 1191
            + +VG  +  RK L   +K +S + L+    GI +M+IE E+ S     + S   F    LK L+S  T +LL  +V YH   + LFM++N  + WR  +T +    I +EL ICAIH  PIP  Y + WTT    L    K    E VP DV +++ MFLR YLI RVM+LHS ++ ++SSR +  +   + N++F LK L+TI     L+V ++ + +  SW +R CE +  + +    N++W  AITF+ +GYGDIVP + CGR I +  G+ G   TA +VA+++  L+L+ +E ++H F++D+ L K +K  A  +++  W
Sbjct:  223 KPNVGYRLGKRKALFEKRKRISDYALVMGMFGIIVMVIENELSSAGVYTKAS---FYSTALKTLISVSTVILLGLIVAYHALEVQLFMIDNCADDWRIAMTWQRISQIGLELFICAIH--PIPGEYYFQWTTK---LANKNKTIGTEMVPYDVALSLPMFLRLYLICRVMLLHSKLFTDASSRSIGALNRINFNTRFVLKTLMTICPGTVLLVFMVSLWIIASWTLRQCERFHDEEHANLLNSMWLTAITFLCVGYGDIVPNTYCGRGITLTCGMVGAGCTALLVAVVSRKLELTRAEKHVHNFMMDTQLTKRLKNAAANVLRETW 540          
BLAST of Small conductance calcium-activated potassium channel protein 2 vs. Ensembl Zebrafish
Match: kcnn2 (potassium calcium-activated channel subfamily N member 2 [Source:ZFIN;Acc:ZDB-GENE-091116-41])

HSP 1 Score: 212.231 bits (539), Expect = 8.225e-62
Identity = 122/323 (37.77%), Postives = 193/323 (59.75%), Query Frame = 1
Query:  232 KSVGSTMSTRKCLHNNQKILSIFCLIFAAVGIGLMIIEIEIVSYNASNQISQLCFVCFFLKVLVSFFTGLLLICLVFYHRASILLFMVENNLNSWRFVITVRLSLSIFIELAICAIHAPPIP-NYNYVWTTYRLILGRPEKEDVPLDVIITIIMFLRGYLIFRVMVLHSHVYDNSSSRCVELMQGKSINSQFALKYLLTIYSKAFLIVSVICVILWTSWAVRVCEIYEKDSNL--RFFNNIWFIAITFMTIGYGDIVPRSVCGRFIAVLSGVFGVMYTAYVVAIIAXXXXXXXXXXXXHQFVVDSDLDKSIKEQAVIIIQNFW 1191
            +++G  +  R+ L   +K LS + LIF   GI +M+IE E+ S+ A  + S        LK L+S  T +LL  ++ YH   I LFMV+N  + WR  +T      I +E+ +CAIH  PIP NY + WT        P K D  +D+I++I MFLR YLI RVM+LHS ++ ++SSR +  +   + N++F +K L+TI     L+V  I + +  +W VR CE Y  + ++   F   +W I+ITF+TIGYGD+VP + CG+ + +L+G+ G   TA VVA++A+ L+L+ +E ++H F++D+ L K +K  A  +++  W
Sbjct:  101 QNIGQKLGHRRALFEKRKRLSDYALIFGMFGIVVMVIETEL-SWGAYGKES---LYSLALKCLISLSTIILLGLIIIYHAREIQLFMVDNAADDWRIAMTYERIFFICLEILVCAIH--PIPGNYTFTWTARLAFSYAPSKTDADVDIILSIPMFLRLYLIARVMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFTISLWIIAAWTVRACERYHDNMDVTSNFLGAMWLISITFLTIGYGDMVPNTYCGKGVCLLTGIMGAGCTALVVAVVAKKLELTKAEKHVHNFMMDTQLTKRVKNTAANVLRETW 417          
BLAST of Small conductance calcium-activated potassium channel protein 2 vs. Ensembl Zebrafish
Match: kcnn1a (potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1a [Source:ZFIN;Acc:ZDB-GENE-070912-703])

HSP 1 Score: 208.379 bits (529), Expect = 1.405e-60
Identity = 122/327 (37.31%), Postives = 187/327 (57.19%), Query Frame = 1
Query:  220 QITRKSVGSTMSTRKCLHNNQKILSIFCLIFAAVGIGLMIIEIEIVSYNASNQISQLCFVCFFLKVLVSFFTGLLLICLVFYHRASILLFMVENNLNSWRFVITVRLSLSIFIELAICAIHAPPIPN-YNYVWTTYRLILGRPEKEDVPLDVIITIIMFLRGYLIFRVMVLHSHVYDNSSSRCVELMQGKSINSQFALKYLLTIYSKAFLIVSVICVILWTSWAVRVCEIYEKDSNL--RFFNNIWFIAITFMTIGYGDIVPRSVCGRFIAVLSGVFGVMYTAYVVAIIAXXXXXXXXXXXXHQFVVDSDLDKSIKEQAVIIIQNFW 1191
            Q   K +G  +  R+ L   +K LS + LIF   GI +M+ E E+ S+    + S   F    LK L+S  T +LL  ++ YH   I LFMV+N  + WR  +T      I +EL +CAIH  PIP  Y + WT        P   D  +D+I++I MFLR YLI RVM+LHS ++ ++SSR +  +   + N++F +K L+TI     L+V  I   +  +W VRVCE Y     +   F   +W I+ITF++IGYGD+VP + CG+ + +L+G+ G   TA VVA++A  L+L+ +E ++H F++D+ L K +K  A  +++  W
Sbjct:   71 QKKNKDIGYKLGHRRALFEKRKRLSDYALIFGMFGIVVMVTETEL-SWGVYTKESSYSFA---LKCLISLSTVILLGLIIMYHAREIQLFMVDNGADDWRIAMTYERIFFIVLELLVCAIH--PIPGQYVFTWTARLAFTYVPSVADADVDIILSIPMFLRLYLIGRVMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFSISSWIIAAWTVRVCERYHDKQEVTSNFLGAMWLISITFLSIGYGDMVPHTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLCKRVKNTAANVLRETW 391          
BLAST of Small conductance calcium-activated potassium channel protein 2 vs. Ensembl Zebrafish
Match: kcnn1b (potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1b [Source:ZFIN;Acc:ZDB-GENE-060503-397])

HSP 1 Score: 207.223 bits (526), Expect = 5.181e-60
Identity = 124/325 (38.15%), Postives = 188/325 (57.85%), Query Frame = 1
Query:  232 KSVGSTMSTRKCLHNNQKILSIFCLIFAAVGIGLMIIEIEIVSYNASNQISQLCFVCFFLKVLVSFFTGLLLICLVFYHRASILLFMVENNLNSWRFVITVRLSLSIFIELAICAIHAPPIPN-YNYVWTTYRLILGRPEKEDVPLDVIITIIMFLRGYLIFRVMVLHSHVYDNSSSRCVELMQGKSINSQFALKYLLTIYSKAFLIVSVICVILWTSWAVRVCEIY----EKDSNLRFFNNIWFIAITFMTIGYGDIVPRSVCGRFIAVLSGVFGVMYTAYVVAIIAXXXXXXXXXXXXHQFVVDSDLDKSIKEQAVIIIQNFW 1191
            K +G  +  R+ L   +K LS + LIF   GI +M+ E E+ S+    + S   F    LK L+S  T +LL  ++ YH   I LFMV+N  + WR  +T    L I +EL +CAIH  PIP  Y + WT        P   D  +D+I++I MFLR YLI RVM+LHS ++ ++SSR +  +   + N++F +K L+TI     L+V  I   +  +W V VCE Y    E  SN  F   +W I+ITF++IGYGD+VP + CG+ + +L+G+ G   TA VVA++A  L+L+ +E ++H F++D+ L K +K  A  +++  W
Sbjct:   76 KDIGYKLGHRRALFEKRKRLSDYALIFGMFGIVVMVTETEL-SWGVYTKESSYSFA---LKCLISLSTVILLCLIIMYHAREIQLFMVDNGADDWRIAMTYERILFIVLELLVCAIH--PIPGQYVFTWTARLAFTYTPSVADADVDIILSIPMFLRLYLIGRVMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFSISSWIIAAWTVHVCERYHDKVEVTSN--FLGAMWLISITFLSIGYGDMVPNTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLCKRVKNTAANVLRETW 392          
BLAST of Small conductance calcium-activated potassium channel protein 2 vs. Ensembl Zebrafish
Match: kcnn1b (potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1b [Source:ZFIN;Acc:ZDB-GENE-060503-397])

HSP 1 Score: 206.838 bits (525), Expect = 5.467e-60
Identity = 124/325 (38.15%), Postives = 188/325 (57.85%), Query Frame = 1
Query:  232 KSVGSTMSTRKCLHNNQKILSIFCLIFAAVGIGLMIIEIEIVSYNASNQISQLCFVCFFLKVLVSFFTGLLLICLVFYHRASILLFMVENNLNSWRFVITVRLSLSIFIELAICAIHAPPIPN-YNYVWTTYRLILGRPEKEDVPLDVIITIIMFLRGYLIFRVMVLHSHVYDNSSSRCVELMQGKSINSQFALKYLLTIYSKAFLIVSVICVILWTSWAVRVCEIY----EKDSNLRFFNNIWFIAITFMTIGYGDIVPRSVCGRFIAVLSGVFGVMYTAYVVAIIAXXXXXXXXXXXXHQFVVDSDLDKSIKEQAVIIIQNFW 1191
            K +G  +  R+ L   +K LS + LIF   GI +M+ E E+ S+    + S   F    LK L+S  T +LL  ++ YH   I LFMV+N  + WR  +T    L I +EL +CAIH  PIP  Y + WT        P   D  +D+I++I MFLR YLI RVM+LHS ++ ++SSR +  +   + N++F +K L+TI     L+V  I   +  +W V VCE Y    E  SN  F   +W I+ITF++IGYGD+VP + CG+ + +L+G+ G   TA VVA++A  L+L+ +E ++H F++D+ L K +K  A  +++  W
Sbjct:   76 KDIGYKLGHRRALFEKRKRLSDYALIFGMFGIVVMVTETEL-SWGVYTKESSYSFA---LKCLISLSTVILLCLIIMYHAREIQLFMVDNGADDWRIAMTYERILFIVLELLVCAIH--PIPGQYVFTWTARLAFTYTPSVADADVDIILSIPMFLRLYLIGRVMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFSISSWIIAAWTVHVCERYHDKVEVTSN--FLGAMWLISITFLSIGYGDMVPNTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLCKRVKNTAANVLRETW 392          
BLAST of Small conductance calcium-activated potassium channel protein 2 vs. Ensembl Zebrafish
Match: kcnn1b (potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1b [Source:ZFIN;Acc:ZDB-GENE-060503-397])

HSP 1 Score: 198.364 bits (503), Expect = 6.205e-59
Identity = 118/316 (37.34%), Postives = 182/316 (57.59%), Query Frame = 1
Query:  274 NNQKILSIFCLIFAAVGIGLMIIEIEIVSYNASNQISQLCFVCFFLKVLVSFFTGLLLICLVFYHRASILLFMVENNLNSWRFVITVRLSLSIFIELAICAIHAPPIPN-YNYVWTTYRLILGRPEKEDVPLDVIITIIMFLRGYLIFRVMVLHSHVYDNSSSRCVELMQGKSINSQFALKYLLTIYSKAFLIVSVICVILWTSWAVRVCEIYEKDSNL--RFFNNIWFIAITFMTIGYGDIVPRSVCGRFIAVLSGVFGVMYTAYVVAIIAXXXXXXXXXXXXHQFVVDSDLDKSIKEQAVIIIQNFWRLKRAIK 1212
              +K LS + LIF   GI +M+ E E+ S+    + S   F    LK L+S  T +LL  ++ YH   I LFMV+N  + WR  +T    L I +EL +CAIH  PIP  Y + WT        P   D  +D+I++I MFLR YLI RVM+LHS ++ ++SSR +  +   + N++F +K L+TI     L+V  I   +  +W V VCE Y     +   F   +W I+ITF++IGYGD+VP + CG+ + +L+G+ G   TA VVA++A  L+L+ +E ++H F++D+ L K +K  A  +++  W + +  K
Sbjct:    3 EKRKRLSDYALIFGMFGIVVMVTETEL-SWGVYTKESSYSFA---LKCLISLSTVILLCLIIMYHAREIQLFMVDNGADDWRIAMTYERILFIVLELLVCAIH--PIPGQYVFTWTARLAFTYTPSVADADVDIILSIPMFLRLYLIGRVMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFSISSWIIAAWTVHVCERYHDKVEVTSNFLGAMWLISITFLSIGYGDMVPNTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLCKRVKNTAANVLRETWLIYKHTK 312          
BLAST of Small conductance calcium-activated potassium channel protein 2 vs. Ensembl Xenopus
Match: wdr17 (WD repeat domain 17 [Source:Xenbase;Acc:XB-GENE-1000178])

HSP 1 Score: 208.764 bits (530), Expect = 1.059e-60
Identity = 120/327 (36.70%), Postives = 188/327 (57.49%), Query Frame = 1
Query:  220 QITRKSVGSTMSTRKCLHNNQKILSIFCLIFAAVGIGLMIIEIEIVSYNASNQISQLCFVCFFLKVLVSFFTGLLLICLVFYHRASILLFMVENNLNSWRFVITVRLSLSIFIELAICAIHAPPIPN-YNYVWTTYRLILGRPEKEDVPLDVIITIIMFLRGYLIFRVMVLHSHVYDNSSSRCVELMQGKSINSQFALKYLLTIYSKAFLIVSVICVILWTSWAVRVCEIYEKDSNL--RFFNNIWFIAITFMTIGYGDIVPRSVCGRFIAVLSGVFGVMYTAYVVAIIAXXXXXXXXXXXXHQFVVDSDLDKSIKEQAVIIIQNFW 1191
            Q   ++VG  +  R+ L   +K LS + LIF   GI +M+ E E+ S+    + S   F    LK L+S  T +LL  ++ YH   I LFMV+N  + WR  +T      I +EL +CAIH  PIP  Y++ WT            +  +D+I++I MFLR YLI RVM+LHS ++ ++SSR +  +   + N++F +K L+TI     L+V  I   +  +W VRVCE Y     +   F   +W I+ITF++IGYGD+VP + CG+ + +L+G+ G   TA VVA++A  L+L+ +E ++H F++D+ L K +K  A  +++  W
Sbjct:   73 QKKNQNVGYKLGHRRALFEKRKRLSDYALIFGMFGIVVMVTETEL-SWGVYTKESSYSFA---LKCLISLSTAILLGLIIMYHAREIQLFMVDNGADDWRIAMTYERIFFITLELTVCAIH--PIPGQYSFTWTARLAFFYTTSVANADIDIILSIPMFLRLYLIGRVMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFSISSWIIAAWTVRVCERYHDKQEVTSNFLGAMWLISITFLSIGYGDMVPNTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLSKRVKNAAANVLRETW 393          
BLAST of Small conductance calcium-activated potassium channel protein 2 vs. Ensembl Xenopus
Match: wdr17 (WD repeat domain 17 [Source:Xenbase;Acc:XB-GENE-1000178])

HSP 1 Score: 208.764 bits (530), Expect = 1.255e-60
Identity = 120/327 (36.70%), Postives = 188/327 (57.49%), Query Frame = 1
Query:  220 QITRKSVGSTMSTRKCLHNNQKILSIFCLIFAAVGIGLMIIEIEIVSYNASNQISQLCFVCFFLKVLVSFFTGLLLICLVFYHRASILLFMVENNLNSWRFVITVRLSLSIFIELAICAIHAPPIPN-YNYVWTTYRLILGRPEKEDVPLDVIITIIMFLRGYLIFRVMVLHSHVYDNSSSRCVELMQGKSINSQFALKYLLTIYSKAFLIVSVICVILWTSWAVRVCEIYEKDSNL--RFFNNIWFIAITFMTIGYGDIVPRSVCGRFIAVLSGVFGVMYTAYVVAIIAXXXXXXXXXXXXHQFVVDSDLDKSIKEQAVIIIQNFW 1191
            Q   ++VG  +  R+ L   +K LS + LIF   GI +M+ E E+ S+    + S   F    LK L+S  T +LL  ++ YH   I LFMV+N  + WR  +T      I +EL +CAIH  PIP  Y++ WT            +  +D+I++I MFLR YLI RVM+LHS ++ ++SSR +  +   + N++F +K L+TI     L+V  I   +  +W VRVCE Y     +   F   +W I+ITF++IGYGD+VP + CG+ + +L+G+ G   TA VVA++A  L+L+ +E ++H F++D+ L K +K  A  +++  W
Sbjct:   65 QKKNQNVGYKLGHRRALFEKRKRLSDYALIFGMFGIVVMVTETEL-SWGVYTKESSYSFA---LKCLISLSTAILLGLIIMYHAREIQLFMVDNGADDWRIAMTYERIFFITLELTVCAIH--PIPGQYSFTWTARLAFFYTTSVANADIDIILSIPMFLRLYLIGRVMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFSISSWIIAAWTVRVCERYHDKQEVTSNFLGAMWLISITFLSIGYGDMVPNTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLSKRVKNAAANVLRETW 385          
BLAST of Small conductance calcium-activated potassium channel protein 2 vs. Ensembl Xenopus
Match: wdr17 (WD repeat domain 17 [Source:Xenbase;Acc:XB-GENE-1000178])

HSP 1 Score: 208.764 bits (530), Expect = 1.576e-60
Identity = 120/327 (36.70%), Postives = 188/327 (57.49%), Query Frame = 1
Query:  220 QITRKSVGSTMSTRKCLHNNQKILSIFCLIFAAVGIGLMIIEIEIVSYNASNQISQLCFVCFFLKVLVSFFTGLLLICLVFYHRASILLFMVENNLNSWRFVITVRLSLSIFIELAICAIHAPPIPN-YNYVWTTYRLILGRPEKEDVPLDVIITIIMFLRGYLIFRVMVLHSHVYDNSSSRCVELMQGKSINSQFALKYLLTIYSKAFLIVSVICVILWTSWAVRVCEIYEKDSNL--RFFNNIWFIAITFMTIGYGDIVPRSVCGRFIAVLSGVFGVMYTAYVVAIIAXXXXXXXXXXXXHQFVVDSDLDKSIKEQAVIIIQNFW 1191
            Q   ++VG  +  R+ L   +K LS + LIF   GI +M+ E E+ S+    + S   F    LK L+S  T +LL  ++ YH   I LFMV+N  + WR  +T      I +EL +CAIH  PIP  Y++ WT            +  +D+I++I MFLR YLI RVM+LHS ++ ++SSR +  +   + N++F +K L+TI     L+V  I   +  +W VRVCE Y     +   F   +W I+ITF++IGYGD+VP + CG+ + +L+G+ G   TA VVA++A  L+L+ +E ++H F++D+ L K +K  A  +++  W
Sbjct:   73 QKKNQNVGYKLGHRRALFEKRKRLSDYALIFGMFGIVVMVTETEL-SWGVYTKESSYSFA---LKCLISLSTAILLGLIIMYHAREIQLFMVDNGADDWRIAMTYERIFFITLELTVCAIH--PIPGQYSFTWTARLAFFYTTSVANADIDIILSIPMFLRLYLIGRVMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFSISSWIIAAWTVRVCERYHDKQEVTSNFLGAMWLISITFLSIGYGDMVPNTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLSKRVKNAAANVLRETW 393          
BLAST of Small conductance calcium-activated potassium channel protein 2 vs. Ensembl Xenopus
Match: wdr17 (WD repeat domain 17 [Source:Xenbase;Acc:XB-GENE-1000178])

HSP 1 Score: 208.379 bits (529), Expect = 4.657e-60
Identity = 120/327 (36.70%), Postives = 188/327 (57.49%), Query Frame = 1
Query:  220 QITRKSVGSTMSTRKCLHNNQKILSIFCLIFAAVGIGLMIIEIEIVSYNASNQISQLCFVCFFLKVLVSFFTGLLLICLVFYHRASILLFMVENNLNSWRFVITVRLSLSIFIELAICAIHAPPIPN-YNYVWTTYRLILGRPEKEDVPLDVIITIIMFLRGYLIFRVMVLHSHVYDNSSSRCVELMQGKSINSQFALKYLLTIYSKAFLIVSVICVILWTSWAVRVCEIYEKDSNL--RFFNNIWFIAITFMTIGYGDIVPRSVCGRFIAVLSGVFGVMYTAYVVAIIAXXXXXXXXXXXXHQFVVDSDLDKSIKEQAVIIIQNFW 1191
            Q   ++VG  +  R+ L   +K LS + LIF   GI +M+ E E+ S+    + S   F    LK L+S  T +LL  ++ YH   I LFMV+N  + WR  +T      I +EL +CAIH  PIP  Y++ WT            +  +D+I++I MFLR YLI RVM+LHS ++ ++SSR +  +   + N++F +K L+TI     L+V  I   +  +W VRVCE Y     +   F   +W I+ITF++IGYGD+VP + CG+ + +L+G+ G   TA VVA++A  L+L+ +E ++H F++D+ L K +K  A  +++  W
Sbjct:  110 QKKNQNVGYKLGHRRALFEKRKRLSDYALIFGMFGIVVMVTETEL-SWGVYTKESSYSFA---LKCLISLSTAILLGLIIMYHAREIQLFMVDNGADDWRIAMTYERIFFITLELTVCAIH--PIPGQYSFTWTARLAFFYTTSVANADIDIILSIPMFLRLYLIGRVMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFSISSWIIAAWTVRVCERYHDKQEVTSNFLGAMWLISITFLSIGYGDMVPNTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLSKRVKNAAANVLRETW 430          
BLAST of Small conductance calcium-activated potassium channel protein 2 vs. Ensembl Xenopus
Match: KCNN2 (potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 [Source:NCBI gene;Acc:100145581])

HSP 1 Score: 209.534 bits (532), Expect = 5.989e-60
Identity = 120/323 (37.15%), Postives = 191/323 (59.13%), Query Frame = 1
Query:  232 KSVGSTMSTRKCLHNNQKILSIFCLIFAAVGIGLMIIEIEIVSYNASNQISQLCFVCFFLKVLVSFFTGLLLICLVFYHRASILLFMVENNLNSWRFVITVRLSLSIFIELAICAIHAPPIP-NYNYVWTTYRLILGRPEKEDVPLDVIITIIMFLRGYLIFRVMVLHSHVYDNSSSRCVELMQGKSINSQFALKYLLTIYSKAFLIVSVICVILWTSWAVRVCEIY--EKDSNLRFFNNIWFIAITFMTIGYGDIVPRSVCGRFIAVLSGVFGVMYTAYVVAIIAXXXXXXXXXXXXHQFVVDSDLDKSIKEQAVIIIQNFW 1191
            +++G  +  R+ L   +K LS + LIF   GI +M+IE E+ S+ A ++ S        LK L+S  T +LL  ++ YH   I LFMV+N  + WR  +T      I +E+ +CAIH  PIP NY + WT        P      +D+I++I MFLR YLI RVM+LHS ++ ++SSR +  +   + N++F +K L+TI     L+V  I + +  +W VR CE Y  ++D    F   +W I+ITF++IGYGD+VP + CG+ + +L+G+ G   TA VVA++A  L+L+ +E ++H F++D+ L K +K  A  +++  W
Sbjct:  197 QNIGYKLGHRRALFEKRKRLSDYALIFGMFGIVVMVIETEL-SWGAYDKGS---LYSLALKCLISLSTIILLGLIIVYHAREIQLFMVDNGADDWRIAMTYERIFFICLEILVCAIH--PIPGNYTFTWTARLAFSYTPSTTTADVDIILSIPMFLRLYLIARVMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFSISLWIIAAWTVRACERYHDQQDVTSNFLGAMWLISITFLSIGYGDMVPNTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTKRVKNAAANVLRETW 513          
BLAST of Small conductance calcium-activated potassium channel protein 2 vs. Ensembl Mouse
Match: Kcnn2 (potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2 [Source:MGI Symbol;Acc:MGI:2153182])

HSP 1 Score: 210.69 bits (535), Expect = 4.285e-61
Identity = 121/330 (36.67%), Postives = 194/330 (58.79%), Query Frame = 1
Query:  232 KSVGSTMSTRKCLHNNQKILSIFCLIFAAVGIGLMIIEIEIVSYNASNQISQLCFVCFFLKVLVSFFTGLLLICLVFYHRASILLFMVENNLNSWRFVITVRLSLSIFIELAICAIHAPPIP-NYNYVWTTYRLILGRPEKEDVPLDVIITIIMFLRGYLIFRVMVLHSHVYDNSSSRCVELMQGKSINSQFALKYLLTIYSKAFLIVSVICVILWTSWAVRVCEIY--EKDSNLRFFNNIWFIAITFMTIGYGDIVPRSVCGRFIAVLSGVFGVMYTAYVVAIIAXXXXXXXXXXXXHQFVVDSDLDKSIKEQAVIIIQNFWRLKRAIK 1212
            +++G  +  R+ L   +K LS + LIF   GI +M+IE E+ S+ A ++ S        LK L+S  T +LL  ++ YH   I LFMV+N  + WR  +T      I +E+ +CAIH  PIP NY + WT        P      +D+I++I MFLR YLI RVM+LHS ++ ++SSR +  +   + N++F +K L+TI     L+V  I + +  +W VR CE Y  ++D    F   +W I+ITF++IGYGD+VP + CG+ + +L+G+ G   TA VVA++A  L+L+ +E ++H F++D+ L K +K  A  +++  W + +  K
Sbjct:  110 QNIGYKLGHRRALFEKRKRLSDYALIFGMFGIVVMVIETEL-SWGAYDKAS---LYSLALKCLISLSTIILLGLIIVYHAREIQLFMVDNGADDWRIAMTYERIFFICLEILVCAIH--PIPGNYTFTWTARLAFSYAPSTTTADVDIILSIPMFLRLYLIARVMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFSISLWIIAAWTVRACERYHDQQDVTSNFLGAMWLISITFLSIGYGDMVPNTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTKRVKNAAANVLRETWLIYKNTK 433          
BLAST of Small conductance calcium-activated potassium channel protein 2 vs. Ensembl Mouse
Match: Kcnn2 (potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2 [Source:MGI Symbol;Acc:MGI:2153182])

HSP 1 Score: 210.69 bits (535), Expect = 4.285e-61
Identity = 121/330 (36.67%), Postives = 194/330 (58.79%), Query Frame = 1
Query:  232 KSVGSTMSTRKCLHNNQKILSIFCLIFAAVGIGLMIIEIEIVSYNASNQISQLCFVCFFLKVLVSFFTGLLLICLVFYHRASILLFMVENNLNSWRFVITVRLSLSIFIELAICAIHAPPIP-NYNYVWTTYRLILGRPEKEDVPLDVIITIIMFLRGYLIFRVMVLHSHVYDNSSSRCVELMQGKSINSQFALKYLLTIYSKAFLIVSVICVILWTSWAVRVCEIY--EKDSNLRFFNNIWFIAITFMTIGYGDIVPRSVCGRFIAVLSGVFGVMYTAYVVAIIAXXXXXXXXXXXXHQFVVDSDLDKSIKEQAVIIIQNFWRLKRAIK 1212
            +++G  +  R+ L   +K LS + LIF   GI +M+IE E+ S+ A ++ S        LK L+S  T +LL  ++ YH   I LFMV+N  + WR  +T      I +E+ +CAIH  PIP NY + WT        P      +D+I++I MFLR YLI RVM+LHS ++ ++SSR +  +   + N++F +K L+TI     L+V  I + +  +W VR CE Y  ++D    F   +W I+ITF++IGYGD+VP + CG+ + +L+G+ G   TA VVA++A  L+L+ +E ++H F++D+ L K +K  A  +++  W + +  K
Sbjct:  110 QNIGYKLGHRRALFEKRKRLSDYALIFGMFGIVVMVIETEL-SWGAYDKAS---LYSLALKCLISLSTIILLGLIIVYHAREIQLFMVDNGADDWRIAMTYERIFFICLEILVCAIH--PIPGNYTFTWTARLAFSYAPSTTTADVDIILSIPMFLRLYLIARVMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFSISLWIIAAWTVRACERYHDQQDVTSNFLGAMWLISITFLSIGYGDMVPNTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTKRVKNAAANVLRETWLIYKNTK 433          
BLAST of Small conductance calcium-activated potassium channel protein 2 vs. Ensembl Mouse
Match: Kcnn3 (potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3 [Source:MGI Symbol;Acc:MGI:2153183])

HSP 1 Score: 208.379 bits (529), Expect = 3.656e-59
Identity = 121/341 (35.48%), Postives = 199/341 (58.36%), Query Frame = 1
Query:  199 TYFEMELQITRKSVGSTMSTRKCLHNNQKILSIFCLIFAAVGIGLMIIEIEIVSYNASNQISQLCFVCFFLKVLVSFFTGLLLICLVFYHRASILLFMVENNLNSWRFVITVRLSLSIFIELAICAIHAPPIPN-YNYVWTTYRLILGRPEKEDVPLDVIITIIMFLRGYLIFRVMVLHSHVYDNSSSRCVELMQGKSINSQFALKYLLTIYSKAFLIVSVICVILWTSWAVRVCEIY--EKDSNLRFFNNIWFIAITFMTIGYGDIVPRSVCGRFIAVLSGVFGVMYTAYVVAIIAXXXXXXXXXXXXHQFVVDSDLDKSIKEQAVIIIQNFWRLKRAIK 1212
            T F    +   +++G  +  R+ L   +K LS + LIF   GI +M+IE E+ S+   ++ S        LK L+S  T +LL  ++ YH   + LF+++N  + WR  +T    L I +E+ +CAIH  PIP  Y + WT        P + +  +D+I++I MFLR YLI RVM+LHS ++ ++SSR +  +   + N++F +K L+TI     L+V  I + +  +W VRVCE Y  ++D    F   +W I+ITF++IGYGD+VP + CG+ + +L+G+ G   TA VVA++A  L+L+ +E ++H F++D+ L K IK  A  +++  W + +  K
Sbjct:  254 TTFPKANKRKNQNIGYKLGHRRALFEKRKRLSDYALIFGMFGIVVMVIETEL-SWGLYSKDSMFSLA---LKCLISLSTVILLGLIIAYHTREVQLFVIDNGADDWRIAMTYERILYISLEMLVCAIH--PIPGEYKFFWTARLAFSYTPSRAEADVDIILSIPMFLRLYLIARVMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFSISLWIIAAWTVRVCERYHDQQDVTSNFLGAMWLISITFLSIGYGDMVPHTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTKRIKNAAANVLRETWLIYKHTK 588          
BLAST of Small conductance calcium-activated potassium channel protein 2 vs. Ensembl Mouse
Match: Kcnn2 (potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2 [Source:MGI Symbol;Acc:MGI:2153182])

HSP 1 Score: 209.534 bits (532), Expect = 4.952e-59
Identity = 121/330 (36.67%), Postives = 194/330 (58.79%), Query Frame = 1
Query:  232 KSVGSTMSTRKCLHNNQKILSIFCLIFAAVGIGLMIIEIEIVSYNASNQISQLCFVCFFLKVLVSFFTGLLLICLVFYHRASILLFMVENNLNSWRFVITVRLSLSIFIELAICAIHAPPIP-NYNYVWTTYRLILGRPEKEDVPLDVIITIIMFLRGYLIFRVMVLHSHVYDNSSSRCVELMQGKSINSQFALKYLLTIYSKAFLIVSVICVILWTSWAVRVCEIY--EKDSNLRFFNNIWFIAITFMTIGYGDIVPRSVCGRFIAVLSGVFGVMYTAYVVAIIAXXXXXXXXXXXXHQFVVDSDLDKSIKEQAVIIIQNFWRLKRAIK 1212
            +++G  +  R+ L   +K LS + LIF   GI +M+IE E+ S+ A ++ S        LK L+S  T +LL  ++ YH   I LFMV+N  + WR  +T      I +E+ +CAIH  PIP NY + WT        P      +D+I++I MFLR YLI RVM+LHS ++ ++SSR +  +   + N++F +K L+TI     L+V  I + +  +W VR CE Y  ++D    F   +W I+ITF++IGYGD+VP + CG+ + +L+G+ G   TA VVA++A  L+L+ +E ++H F++D+ L K +K  A  +++  W + +  K
Sbjct:  375 QNIGYKLGHRRALFEKRKRLSDYALIFGMFGIVVMVIETEL-SWGAYDKAS---LYSLALKCLISLSTIILLGLIIVYHAREIQLFMVDNGADDWRIAMTYERIFFICLEILVCAIH--PIPGNYTFTWTARLAFSYAPSTTTADVDIILSIPMFLRLYLIARVMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFSISLWIIAAWTVRACERYHDQQDVTSNFLGAMWLISITFLSIGYGDMVPNTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTKRVKNAAANVLRETWLIYKNTK 698          
BLAST of Small conductance calcium-activated potassium channel protein 2 vs. Ensembl Mouse
Match: Kcnn1 (potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1 [Source:MGI Symbol;Acc:MGI:1933993])

HSP 1 Score: 204.142 bits (518), Expect = 6.176e-59
Identity = 121/323 (37.46%), Postives = 191/323 (59.13%), Query Frame = 1
Query:  235 SVGSTMSTRKCLHNNQKILSIFCLIFAAVGIGLMIIEIEIVSYNASNQISQLCFVCFFLKVLVSFFTGLLLICLVFYHRASILLFMVENNLNSWRFVIT-VRLSLSIFIELAICAIHAPPIP-NYNYVWTTYRLILGRPEKEDVPLDVIITIIMFLRGYLIFRVMVLHSHVYDNSSSRCVELMQGKSINSQFALKYLLTIYSKAFLIVSVICVILWTSWAVRVCEIYEKDSNL--RFFNNIWFIAITFMTIGYGDIVPRSVCGRFIAVLSGVFGVMYTAYVVAIIAXXXXXXXXXXXXHQFVVDSDLDKSIKEQAVIIIQNFW 1191
            +V   +  R+ L   +K LS + LIF   GI +M+ E E+ S+    + S LC   F LK L+S  T +LL  ++ YH   I LF+V+N  + WR  +T  R+SL I +EL +CAIH  P+P +Y + WT        P   +  LDV+++I MFLR YL+ RVM+LHS ++ ++SSR +  +   + N++F  K L+TI     L+V  +   +  +W VRVCE Y     +   F   +W I+ITF++IGYGD+VP + CG+ + +L+G+ G   TA VVA++A  L+L+ +E ++H F++D+ L K +K  A  +++  W
Sbjct:   86 TVSHRLGHRRALFEKRKRLSDYALIFGMFGIVVMVTETEL-SWGVYTKES-LC--SFALKCLISLSTVILLGLVILYHAREIQLFLVDNGADDWRIAMTWERVSL-ISLELVVCAIH--PVPGHYRFTWTARLAFSLVPSAAEADLDVLLSIPMFLRLYLLARVMLLHSRIFTDASSRSIGALNRVTFNTRFVTKTLMTICPGTVLLVFSVSSWIVAAWTVRVCERYHDKQEVTSNFLGAMWLISITFLSIGYGDMVPHTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTKRVKNAAANVLRETW 401          
BLAST of Small conductance calcium-activated potassium channel protein 2 vs. UniProt/SwissProt
Match: sp|Q92952|KCNN1_HUMAN (Small conductance calcium-activated potassium channel protein 1 OS=Homo sapiens OX=9606 GN=KCNN1 PE=2 SV=2)

HSP 1 Score: 212.616 bits (540), Expect = 3.529e-61
Identity = 120/322 (37.27%), Postives = 188/322 (58.39%), Query Frame = 1
Query:  235 SVGSTMSTRKCLHNNQKILSIFCLIFAAVGIGLMIIEIEIVSYNASNQISQLCFVCFFLKVLVSFFTGLLLICLVFYHRASILLFMVENNLNSWRFVITVRLSLSIFIELAICAIHAPPIP-NYNYVWTTYRLILGRPEKEDVPLDVIITIIMFLRGYLIFRVMVLHSHVYDNSSSRCVELMQGKSINSQFALKYLLTIYSKAFLIVSVICVILWTSWAVRVCEIYEKDSNL--RFFNNIWFIAITFMTIGYGDIVPRSVCGRFIAVLSGVFGVMYTAYVVAIIAXXXXXXXXXXXXHQFVVDSDLDKSIKEQAVIIIQNFW 1191
            +VG  +  R+ L   +K LS + LIF   GI +M+ E E+ S+    + S      F LK L+S  T +LL  +V YH   I LFMV+N  + WR  +T      I +ELA+CAIH  P+P +Y + WT        P   +  +DV+++I MFLR YL+ RVM+LHS ++ ++SSR +  +   + N++F +K L+TI     L+V  I   +  +W VRVCE Y     +   F   +W I+ITF++IGYGD+VP + CG+ + +L+G+ G   TA VVA++A  L+L+ +E ++H F++D+ L K +K  A  +++  W
Sbjct:   88 NVGHRLGHRRALFEKRKRLSDYALIFGMFGIVVMVTETEL-SWGVYTKES---LYSFALKCLISLSTAILLGLVVLYHAREIQLFMVDNGADDWRIAMTCERVFLISLELAVCAIH--PVPGHYRFTWTARLAFTYAPSVAEADVDVLLSIPMFLRLYLLGRVMLLHSKIFTDASSRSIGALNKITFNTRFVMKTLMTICPGTVLLVFSISSWIIAAWTVRVCERYHDKQEVTSNFLGAMWLISITFLSIGYGDMVPHTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTKRVKNAAANVLRETW 403          
BLAST of Small conductance calcium-activated potassium channel protein 2 vs. UniProt/SwissProt
Match: sp|Q9H2S1|KCNN2_HUMAN (Small conductance calcium-activated potassium channel protein 2 OS=Homo sapiens OX=9606 GN=KCNN2 PE=1 SV=2)

HSP 1 Score: 210.69 bits (535), Expect = 3.038e-60
Identity = 121/330 (36.67%), Postives = 194/330 (58.79%), Query Frame = 1
Query:  232 KSVGSTMSTRKCLHNNQKILSIFCLIFAAVGIGLMIIEIEIVSYNASNQISQLCFVCFFLKVLVSFFTGLLLICLVFYHRASILLFMVENNLNSWRFVITVRLSLSIFIELAICAIHAPPIP-NYNYVWTTYRLILGRPEKEDVPLDVIITIIMFLRGYLIFRVMVLHSHVYDNSSSRCVELMQGKSINSQFALKYLLTIYSKAFLIVSVICVILWTSWAVRVCEIY--EKDSNLRFFNNIWFIAITFMTIGYGDIVPRSVCGRFIAVLSGVFGVMYTAYVVAIIAXXXXXXXXXXXXHQFVVDSDLDKSIKEQAVIIIQNFWRLKRAIK 1212
            +++G  +  R+ L   +K LS + LIF   GI +M+IE E+ S+ A ++ S        LK L+S  T +LL  ++ YH   I LFMV+N  + WR  +T      I +E+ +CAIH  PIP NY + WT        P      +D+I++I MFLR YLI RVM+LHS ++ ++SSR +  +   + N++F +K L+TI     L+V  I + +  +W VR CE Y  ++D    F   +W I+ITF++IGYGD+VP + CG+ + +L+G+ G   TA VVA++A  L+L+ +E ++H F++D+ L K +K  A  +++  W + +  K
Sbjct:  115 QNIGYKLGHRRALFEKRKRLSDYALIFGMFGIVVMVIETEL-SWGAYDKAS---LYSLALKCLISLSTIILLGLIIVYHAREIQLFMVDNGADDWRIAMTYERIFFICLEILVCAIH--PIPGNYTFTWTARLAFSYAPSTTTADVDIILSIPMFLRLYLIARVMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFSISLWIIAAWTVRACERYHDQQDVTSNFLGAMWLISITFLSIGYGDMVPNTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTKRVKNAAANVLRETWLIYKNTK 438          
BLAST of Small conductance calcium-activated potassium channel protein 2 vs. UniProt/SwissProt
Match: sp|P70604|KCNN2_RAT (Small conductance calcium-activated potassium channel protein 2 OS=Rattus norvegicus OX=10116 GN=Kcnn2 PE=1 SV=1)

HSP 1 Score: 210.69 bits (535), Expect = 3.399e-60
Identity = 121/330 (36.67%), Postives = 194/330 (58.79%), Query Frame = 1
Query:  232 KSVGSTMSTRKCLHNNQKILSIFCLIFAAVGIGLMIIEIEIVSYNASNQISQLCFVCFFLKVLVSFFTGLLLICLVFYHRASILLFMVENNLNSWRFVITVRLSLSIFIELAICAIHAPPIP-NYNYVWTTYRLILGRPEKEDVPLDVIITIIMFLRGYLIFRVMVLHSHVYDNSSSRCVELMQGKSINSQFALKYLLTIYSKAFLIVSVICVILWTSWAVRVCEIY--EKDSNLRFFNNIWFIAITFMTIGYGDIVPRSVCGRFIAVLSGVFGVMYTAYVVAIIAXXXXXXXXXXXXHQFVVDSDLDKSIKEQAVIIIQNFWRLKRAIK 1212
            +++G  +  R+ L   +K LS + LIF   GI +M+IE E+ S+ A ++ S        LK L+S  T +LL  ++ YH   I LFMV+N  + WR  +T      I +E+ +CAIH  PIP NY + WT        P      +D+I++I MFLR YLI RVM+LHS ++ ++SSR +  +   + N++F +K L+TI     L+V  I + +  +W VR CE Y  ++D    F   +W I+ITF++IGYGD+VP + CG+ + +L+G+ G   TA VVA++A  L+L+ +E ++H F++D+ L K +K  A  +++  W + +  K
Sbjct:  116 QNIGYKLGHRRALFEKRKRLSDYALIFGMFGIVVMVIETEL-SWGAYDKAS---LYSLALKCLISLSTIILLGLIIVYHAREIQLFMVDNGADDWRIAMTYERIFFICLEILVCAIH--PIPGNYTFTWTARLAFSYAPSTTTADVDIILSIPMFLRLYLIARVMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFSISLWIIAAWTVRACERYHDQQDVTSNFLGAMWLISITFLSIGYGDMVPNTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTKRVKNAAANVLRETWLIYKNTK 439          
BLAST of Small conductance calcium-activated potassium channel protein 2 vs. UniProt/SwissProt
Match: sp|P70606|KCNN1_RAT (Small conductance calcium-activated potassium channel protein 1 OS=Rattus norvegicus OX=10116 GN=Kcnn1 PE=1 SV=2)

HSP 1 Score: 206.068 bits (523), Expect = 8.309e-59
Identity = 122/323 (37.77%), Postives = 192/323 (59.44%), Query Frame = 1
Query:  235 SVGSTMSTRKCLHNNQKILSIFCLIFAAVGIGLMIIEIEIVSYNASNQISQLCFVCFFLKVLVSFFTGLLLICLVFYHRASILLFMVENNLNSWRFVIT-VRLSLSIFIELAICAIHAPPIP-NYNYVWTTYRLILGRPEKEDVPLDVIITIIMFLRGYLIFRVMVLHSHVYDNSSSRCVELMQGKSINSQFALKYLLTIYSKAFLIVSVICVILWTSWAVRVCEIYEKDSNL--RFFNNIWFIAITFMTIGYGDIVPRSVCGRFIAVLSGVFGVMYTAYVVAIIAXXXXXXXXXXXXHQFVVDSDLDKSIKEQAVIIIQNFW 1191
            +V   +  R+ L   +K LS + LIF   GI +M+ E E+ S+    + S LC   F LK L+S  T +LL  ++ YH   I LF+V+N  + WR  +T  R+SL I +ELA+CAIH  P+P +Y + WT        P   +  +DV+++I MFLR YL+ RVM+LHS ++ ++SSR +  +   + N++F  K L+TI     L+V  I   +  +W VRVCE Y     +   F   +W I+ITF++IGYGD+VP + CG+ + +L+G+ G   TA VVA++A  L+L+ +E ++H F++D+ L K +K  A  +++  W
Sbjct:   84 TVSHRLGHRRALFEKRKRLSDYALIFGMFGIVVMVTETEL-SWGVYTKES-LC--SFALKCLISLSTVILLGLVILYHAREIQLFLVDNGADDWRIAMTWERVSL-ISLELAVCAIH--PVPGHYRFTWTARLAFSLVPSAAEADVDVLLSIPMFLRLYLLARVMLLHSRIFTDASSRSIGALNRVTFNTRFVTKTLMTICPGTVLLVFSISSWIVAAWTVRVCERYHDKQEVTSNFLGAMWLISITFLSIGYGDMVPHTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTKRVKNAAANVLRETW 399          
BLAST of Small conductance calcium-activated potassium channel protein 2 vs. UniProt/SwissProt
Match: sp|P58391|KCNN3_MOUSE (Small conductance calcium-activated potassium channel protein 3 OS=Mus musculus OX=10090 GN=Kcnn3 PE=1 SV=2)

HSP 1 Score: 208.379 bits (529), Expect = 2.557e-58
Identity = 121/341 (35.48%), Postives = 199/341 (58.36%), Query Frame = 1
Query:  199 TYFEMELQITRKSVGSTMSTRKCLHNNQKILSIFCLIFAAVGIGLMIIEIEIVSYNASNQISQLCFVCFFLKVLVSFFTGLLLICLVFYHRASILLFMVENNLNSWRFVITVRLSLSIFIELAICAIHAPPIPN-YNYVWTTYRLILGRPEKEDVPLDVIITIIMFLRGYLIFRVMVLHSHVYDNSSSRCVELMQGKSINSQFALKYLLTIYSKAFLIVSVICVILWTSWAVRVCEIY--EKDSNLRFFNNIWFIAITFMTIGYGDIVPRSVCGRFIAVLSGVFGVMYTAYVVAIIAXXXXXXXXXXXXHQFVVDSDLDKSIKEQAVIIIQNFWRLKRAIK 1212
            T F    +   +++G  +  R+ L   +K LS + LIF   GI +M+IE E+ S+   ++ S        LK L+S  T +LL  ++ YH   + LF+++N  + WR  +T    L I +E+ +CAIH  PIP  Y + WT        P + +  +D+I++I MFLR YLI RVM+LHS ++ ++SSR +  +   + N++F +K L+TI     L+V  I + +  +W VRVCE Y  ++D    F   +W I+ITF++IGYGD+VP + CG+ + +L+G+ G   TA VVA++A  L+L+ +E ++H F++D+ L K IK  A  +++  W + +  K
Sbjct:  254 TTFPKANKRKNQNIGYKLGHRRALFEKRKRLSDYALIFGMFGIVVMVIETEL-SWGLYSKDSMFSLA---LKCLISLSTVILLGLIIAYHTREVQLFVIDNGADDWRIAMTYERILYISLEMLVCAIH--PIPGEYKFFWTARLAFSYTPSRAEADVDIILSIPMFLRLYLIARVMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFSISLWIIAAWTVRVCERYHDQQDVTSNFLGAMWLISITFLSIGYGDMVPHTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTKRIKNAAANVLRETWLIYKHTK 588          
BLAST of Small conductance calcium-activated potassium channel protein 2 vs. TrEMBL
Match: A0A1I8FZC7 (CaMBD domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig020603g1 PE=4 SV=1)

HSP 1 Score: 231.491 bits (589), Expect = 6.390e-67
Identity = 141/412 (34.22%), Postives = 241/412 (58.50%), Query Frame = 1
Query:  232 KSVGSTMSTRKCLHNNQKILSIFCLIFAAVGIGLMIIEIEIVSYNASNQISQLCFVCFFLKVLVSFFTGLLLICLVFYHRASILLFMVENNLNSWRFVITVRLSLSIFIELAICAIHAPPIPNYNYVW-----TTYRLILGRPEKEDVPLDVIITIIMFLRGYLIFRVMVLHSHVYDNSSSRCVELMQGKSINSQFALKYLLTIYSKAFLIVSVICVILWTSWAVRVCEIYEKDSNLRFFNNIWFIAITFMTIGYGDIVPRSVCGRFIAVLSGVFGVMYTAYVVAIIAXXXXXXXXXXXXHQFVVDSDLDKSIKEQAVIIIQNFWRLKRAIKTENYDTSDVFRWXXXXXXXXXXXXXXXXXXXQLETKSLRISTLYYSQSQMQQEILQIKNQITNINELISYISNRLQK*LK 1452
            ++VG+ ++ RK L   +K+++   L FA +GI LMI+E E+   N  N+      +   +K L+S  T +LL  + +YH   I +FM++N+++ WR  IT+     + +EL +CA+H  PIP  + V       T R+ L     + +P+DVI ++ MFLR YL+ RVM+LHS +Y ++SS+ +  +     N +F  K L+ +Y +  L V  + + +W SWAVR CE+Y    +  F N++W  AITF+T+GYGDIVP S CGR IAVL+G+FG   TA VVA++A  L+LS +E Y+H FV+D +LDK +K  A  I++  W   +  K  N  T    + + +L+ S   ++  + ++ +L   S+ ++ ++ +Q+ M   +  ++++   +   ++ I ++L + L+
Sbjct:   44 ENVGARLARRKELFVRRKLIADLSLFFAMLGIVLMIVETELCMANVFNKGQPGSII---VKSLISITTAILLGFITWYHYLDIKVFMIDNSIDDWRLAITMSRGFHLALELLVCAVH--PIPGQHEVQMLVYDDTKRVRL----LQVIPIDVIFSLPMFLRFYLVCRVMMLHSRLYQDASSQSLGALNRIHFNFRFIFKSLMNLYPEYVLTVMALFLFIWASWAVRACEMYHGQEHRNFLNSMWMTAITFLTVGYGDIVPASYCGRGIAVLTGLFGTGVTALVVAVLARKLELSRAEKYVHNFVIDIELDKQVKHAAANILKEGWLSYKYKKAGN--TGKTLKHQRRLLHSIHRIRDLRGDQKRLADSSVSLTEMHRNQAFMMTSLTTVQSRSREMESRLARIEDKLDRLLQ 444          
BLAST of Small conductance calcium-activated potassium channel protein 2 vs. TrEMBL
Match: V4B5G3 (CaMBD domain-containing protein OS=Lottia gigantea OX=225164 GN=LOTGIDRAFT_111965 PE=4 SV=1)

HSP 1 Score: 232.261 bits (591), Expect = 5.598e-66
Identity = 125/336 (37.20%), Postives = 209/336 (62.20%), Query Frame = 1
Query:  187 FSLFTYFEMELQITRKSVGSTMSTRKCLHNNQKILSIFCLIFAAVGIGLMIIEIEIVSYNASNQISQLCFVCFFLKVLVSFFTGLLLICLVFYHRASILLFMVENNLNSWRFVITVRLSLSIFIELAICAIHAPPIP-NYNYVWTTYRLILGRPEKEDVPLDVIITIIMFLRGYLIFRVMVLHSHVYDNSSSRCVELMQGKSINSQFALKYLLTIYSKAFLIVSVICVILWTSWAVRVCEIYEKDSNLRFFNNIWFIAITFMTIGYGDIVPRSVCGRFIAVLSGVFGVMYTAYVVAIIAXXXXXXXXXXXXHQFVVDSDLDKSIKEQAVIIIQNFW 1191
            +  +T  + + +  +K+VG  +  RK L+  +K +S +CL+F+  GI +M++E E+   + +   ++  F    L+ L+S  T +LL  ++ YH   + LF V+N +  WR  I+V+  + +F+E+A+CAIH  PIP ++ + WTT +     P    VP+DV+++I MFLR YLI RVM+LHS ++ ++SSR +  +     +++F LK L+TI     L+V ++ + +  SW +R CE Y  +++    N++W IAITF++IGYGDIVP + CGR IA+ +GV G   TA VVA+IA  L+LS +E ++H F++D+ L K +K  A  +++  W
Sbjct:   81 YQKYTEDKTQNKARQKNVGYRLGKRKELYEKRKKISDYCLVFSMFGICVMVLETEL---SMAEVYTKSSFYSIALRSLISISTVILLGLILAYHALEVQLFAVDNCVEDWRIAISVKRGVQVFVEIAVCAIH--PIPGDFTFTWTTPQTENRHPISSVVPVDVVLSIPMFLRLYLICRVMLLHSKLFTDASSRSIGALNRIHFDTRFVLKTLMTICPGTILLVFMLTLWIIASWLLRACESYHDENHANILNSMWMIAITFLSIGYGDIVPNTYCGRGIAIGTGVMGAGCTALVVAVIARKLELSRAEKHVHNFMMDTQLQKRLKNAAANVLRETW 411          
BLAST of Small conductance calcium-activated potassium channel protein 2 vs. TrEMBL
Match: A0A267GF91 (CaMBD domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig023081g1 PE=4 SV=1)

HSP 1 Score: 227.639 bits (579), Expect = 2.759e-65
Identity = 143/418 (34.21%), Postives = 239/418 (57.18%), Query Frame = 1
Query:  232 KSVGSTMSTRKCLHNNQKILSIFCLIFAAVGIGLMIIEIEIVSYNASNQISQLCFVCFFLKVLVSFFTGLLLICLVFYHRASILLFMVENNLNSWRFVITVRLSLSIFIELAICAIHAPPIPNYNYVW-------TTYRLILGRPEKEDVPLDVIITIIMFLRGYLIFRVMVLHSHVYDNSSSRCVELMQGKSINSQFALKYLLTIYSKAFLIVSVICVILWTSWAVRVCEIYEKDSNLRFFNNIWFIAITFMTIGYGDIVPRSVCGRFIAVLSGVFGVMYTAYVVAIIAXXXXXXXXXXXXHQFVVDSDLDKSIKEQAVIIIQNFW---RLKRAIKTENYDTSDVFRWXXXXXXXXXXXXXXXXXXXQLETKSLRISTLYYSQSQMQQEILQIKNQITNINELISYISNRLQK*LKV 1455
            ++VG+ ++ RK L   +K+++   L FA +GI +MIIE E+      N+      V   +K L+S  T +LL  + +YH   I +FM++N+++ WR  IT+     + +EL +CAIH  PIP  + V         + RL+      + +P+DVI ++ MFLR YL+ RVM+LHS +Y ++SS+ +  +     N +F  K L+ +Y +  L V  + + +W SWAVR CE+Y    +  F N++W  AITF+T+GYGDIVP S CGR IAVL+G+FG   TA VVA++A  L+LS +E Y+H FV+D +LDK +K  A  I++  W   + KRA      + +   + + +L+ S   ++  +N++ +L   S+ ++ +Y +Q  M   +  ++ +    +  +  I  +L + L+ 
Sbjct:   53 ENVGARLARRKELFVRRKLIADLSLFFAMLGIVMMIIETELCIAGIFNKAGAGSIV---MKSLISVSTAILLGFISWYHYLDIKVFMIDNSMDDWRLAITLSRGFHLAMELLVCAIH--PIPGQHMVQMLAYDNTNSVRLM------QAIPIDVIFSLPMFLRFYLVCRVMMLHSRLYQDASSQSLGALNRIHFNFRFIFKSLMNLYPEYVLTVMALFLFIWASWAVRACEMYHGPEHRNFLNSMWMTAITFLTVGYGDIVPASYCGRGIAVLTGLFGTGVTALVVAVLARKLELSRAEKYVHNFVIDIELDKQVKHAAANILKEGWLSYKYKRA-----GNATKTLKHQRRLLHSIHRIRELRNDQKRLADSSVSLTEMYRNQGFMLTGLASVQAKAKETDAHLQRIEEKLDRLLQA 454          
BLAST of Small conductance calcium-activated potassium channel protein 2 vs. TrEMBL
Match: A0A1W0WAE1 (Small conductance calcium-activated potassium channel protein OS=Hypsibius dujardini OX=232323 GN=BV898_13565 PE=4 SV=1)

HSP 1 Score: 228.024 bits (580), Expect = 2.115e-63
Identity = 125/332 (37.65%), Postives = 199/332 (59.94%), Query Frame = 1
Query:  199 TYFEMELQITRKSVGSTMSTRKCLHNNQKILSIFCLIFAAVGIGLMIIEIEIVSYNASNQISQLCFVCFFLKVLVSFFTGLLLICLVFYHRASILLFMVENNLNSWRFVITVRLSLSIFIELAICAIHAPPIPNYNYVWTTYRLILGR-PEKEDVPLDVIITIIMFLRGYLIFRVMVLHSHVYDNSSSRCVELMQGKSINSQFALKYLLTIYSKAFLIVSVICVILWTSWAVRVCEIYEKDSNLRFFNNIWFIAITFMTIGYGDIVPRSVCGRFIAVLSGVFGVMYTAYVVAIIAXXXXXXXXXXXXHQFVVDSDLDKSIKEQAVIIIQNFW 1191
            T F    +  + +VG  +  RK L   +K LS + L+F  +GI  M++E E+ +     + S   +    +K +VS  T +L+  +V YH   I LF+++N+ + WR  +T R  L + +EL IC++H PP  ++ + W+       + P  ++VP+DVI+++ MFLR YLIFRVM+LHS ++ ++SSR +  +   + N++F LK L+TI     L+V +I   L  SW +R CE Y    +    N++W IAITF++IGYGDIVP + CGR IAV +G+ G   TA VVA+IA  L+LS +E ++H F++D+ L K +K  A  +++  W
Sbjct:  199 TTFMGSTKFGKPNVGYRLGKRKALFEKRKRLSDYALVFGMIGIAAMMLESELSAGEVYTKSSPWSYT---VKTIVSVSTLILMTLIVGYHGLEIQLFLIDNSADDWRIALTWRRCLQLTVELLICSVHPPP-GHFMFTWSVTLYNHNKDPSSQEVPVDVILSLPMFLRLYLIFRVMLLHSKLFTDASSRSIGALNRINFNTRFVLKTLMTICPGTLLLVFIITYWLIASWTLRACERYHDHEHGNCLNSLWLIAITFLSIGYGDIVPNTYCGRGIAVCTGLMGSGCTALVVAVIARKLELSSAEKHVHNFMMDTQLTKRLKNSAANVLRETW 526          
BLAST of Small conductance calcium-activated potassium channel protein 2 vs. TrEMBL
Match: A0A1D1W8A9 (CaMBD domain-containing protein OS=Ramazzottius varieornatus OX=947166 GN=RvY_19075 PE=4 SV=1)

HSP 1 Score: 228.409 bits (581), Expect = 3.277e-62
Identity = 126/324 (38.89%), Postives = 199/324 (61.42%), Query Frame = 1
Query:  223 ITRKSVGSTMSTRKCLHNNQKILSIFCLIFAAVGIGLMIIEIEIVSYNASNQISQLCFVCFFLKVLVSFFTGLLLICLVFYHRASILLFMVENNLNSWRFVITVRLSLSIFIELAICAIHAPPIPNYNYVWT-TYRLILGRPEKEDVPLDVIITIIMFLRGYLIFRVMVLHSHVYDNSSSRCVELMQGKSINSQFALKYLLTIYSKAFLIVSVICVILWTSWAVRVCEIYEKDSNLRFFNNIWFIAITFMTIGYGDIVPRSVCGRFIAVLSGVFGVMYTAYVVAIIAXXXXXXXXXXXXHQFVVDSDLDKSIKEQAVIIIQNFW 1191
            +++ +VG  +  RK L   +K LS + L+F  +GI  M++E E+ +    N+ S        +K +VS  T +LL  +V YH   I LF+++N+ + WR  +T R    + +EL ICA+H PP  +  ++WT T      RP++ +VP+DVI+++ MFLR YLIFRVM+LHS ++ ++SSR +  +   + N++F LK L+TI     L+V +I   L  +W +R CE Y    +    N++W IAITF+++GYGDIVP + CGR IAV +G+ G   TA VVA+IA  L+LS +E ++H F++D+ L K +K  A  +++  W
Sbjct:  436 LSKPTVGYRLGKRKALFEKRKRLSDYALVFGMIGIAAMMLEAELSAGGVYNKTSAWSIA---VKSIVSVSTLILLTLIVGYHALEIQLFLIDNSADDWRIALTWRRCSQLALELCICAVHPPPG-HLTFLWTATIYNHDKRPKEVEVPVDVILSLPMFLRLYLIFRVMLLHSKLFTDASSRSIGALNRINFNTRFVLKTLMTICPGTLLLVFIITYWLIATWTLRACERYHDYEHANCLNSMWLIAITFLSVGYGDIVPNTYCGRGIAVCTGLMGSGCTALVVAVIARKLELSSAEKHVHNFMMDTQLTKRLKNSAANVLRETW 755          
BLAST of Small conductance calcium-activated potassium channel protein 2 vs. Ensembl Cavefish
Match: kcnn2 (potassium calcium-activated channel subfamily N member 2 [Source:ZFIN;Acc:ZDB-GENE-091116-41])

HSP 1 Score: 207.223 bits (526), Expect = 2.941e-60
Identity = 120/323 (37.15%), Postives = 191/323 (59.13%), Query Frame = 1
Query:  232 KSVGSTMSTRKCLHNNQKILSIFCLIFAAVGIGLMIIEIEIVSYNASNQISQLCFVCFFLKVLVSFFTGLLLICLVFYHRASILLFMVENNLNSWRFVITVRLSLSIFIELAICAIHAPPIPN-YNYVWTTYRLILGRPEKEDVPLDVIITIIMFLRGYLIFRVMVLHSHVYDNSSSRCVELMQGKSINSQFALKYLLTIYSKAFLIVSVICVILWTSWAVRVCEIYEKDSNL--RFFNNIWFIAITFMTIGYGDIVPRSVCGRFIAVLSGVFGVMYTAYVVAIIAXXXXXXXXXXXXHQFVVDSDLDKSIKEQAVIIIQNFW 1191
            +++G  +  R+ L   +K LS + LIF   GI +M+IE E+ S+ A  + S        LK L+S  T +LL  ++ YH   I LFMV+N  + WR  +T      I +E+ +CAIH  PIP  Y + WT          K D  +D+I++I MFLR YLI RVM+LHS ++ ++SSR +  +   + N++F +K L+TI     L+V  I + +  +W VR CE Y  + ++   F   +W I+ITF+TIGYGD+VP + CG+ + +L+G+ G   TA VVA++A+ L+L+ +E ++H F++D+ L K +K  A  +++  W
Sbjct:   84 QNIGQKLGHRRALFEKRKRLSDYALIFGMFGIVVMVIETEL-SWGAYGKES---LYSLALKCLISLSTIILLGLIIIYHAREIQLFMVDNAADDWRIAMTYERIFFICLEILVCAIH--PIPGKYTFTWTARLAFYYTSSKTDADVDIILSIPMFLRLYLIARVMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFTISLWIIAAWTVRACERYHDNQDVTSNFLGAMWLISITFLTIGYGDMVPNTYCGKGVCLLTGIMGAGCTALVVAVVAKKLELTKAEKHVHNFMMDTQLTKRVKNTAANVLRETW 400          
BLAST of Small conductance calcium-activated potassium channel protein 2 vs. Ensembl Cavefish
Match: kcnn3 (potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3 [Source:ZFIN;Acc:ZDB-GENE-100921-56])

HSP 1 Score: 201.83 bits (512), Expect = 6.536e-57
Identity = 115/325 (35.38%), Postives = 192/325 (59.08%), Query Frame = 1
Query:  232 KSVGSTMSTRKCLHNNQKILSIFCLIFAAVGIGLMIIEIEIV--SYNASNQISQLCFVCFFLKVLVSFFTGLLLICLVFYHRASILLFMVENNLNSWRFVITVRLSLSIFIELAICAIHAPPIP-NYNYVWTTYRLILGRPEKEDVPLDVIITIIMFLRGYLIFRVMVLHSHVYDNSSSRCVELMQGKSINSQFALKYLLTIYSKAFLIVSVICVILWTSWAVRVCEIYE--KDSNLRFFNNIWFIAITFMTIGYGDIVPRSVCGRFIAVLSGVFGVMYTAYVVAIIAXXXXXXXXXXXXHQFVVDSDLDKSIKEQAVIIIQNFW 1191
            +++G  +  R+ L   +K LS + LIF   GI +M+IE E+    Y+ S+  S        LK L+S  T +LL  ++ YH   + LF+++N  + WR  +T+   L I +EL + A+H  P+P ++ +VW         P + +  LD+++++ MFLR YLI RVM+LHS ++ ++SSR +  +     N++F +K L+TI     L+V  I + +  +W VRVCE Y   +D    F   +W I+ITF++IGYGD+VP + CG+ + +L+G+ G   TA VVA++A  L+L+ +E ++H F++D+ L K IK  A  +++  W
Sbjct:  244 QNIGYKLGHRRALFEKRKRLSDYALIFGMFGIVVMVIETELSWGVYSKSSMYS------LALKCLISLSTIILLGLIIAYHAREVQLFVIDNGADDWRIAMTMERVLLIALELLVSAVH--PVPGDFKFVWRARLAFTYIPSQAEADLDMVLSVPMFLRLYLIARVMLLHSKLFTDASSRSIGALNKVHFNTRFVMKTLMTICPGTVLLVFSISLWIIAAWTVRVCERYHDAQDVTSNFLGAMWLISITFLSIGYGDMVPHTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTKRIKNAAANVLRETW 560          
BLAST of Small conductance calcium-activated potassium channel protein 2 vs. Ensembl Cavefish
Match: kcnn4 (potassium calcium-activated channel subfamily N member 4 [Source:NCBI gene;Acc:103046778])

HSP 1 Score: 150.214 bits (378), Expect = 1.473e-39
Identity = 101/337 (29.97%), Postives = 180/337 (53.41%), Query Frame = 1
Query:  250 MSTRKCLHNNQKILSIFCLIFAAVGIGLMIIEIEIVSYNASNQISQLCFVCFFLKVLVSFFTGLLLICLVFYHRASILLFMVENNLNSWRFVITVRLSLSIFIELAICAIH------APPI----PNYNYVWTTYRLILGRPEKED-VPLDVIITIIMFLRGYLIFRVMVLHSHVYDNSSSRCVELMQGKSINSQFALKYLLTIYSKAFLIVSVICVILWTSWAVRVCEIYEKDSNLRFFNNIWFIAITFMTIGYGDIVPRSVCGRFIAVLSGVFGVMYTAYVVAIIAXXXXXXXXXXXXHQFVVDSDLDKSIKEQAVIIIQNFWRLKRAIKTENYD 1227
            +  RK L  +++ L  + L  A +GI LMI   E+    A  Q   +  +   +  L+SF TG LLI ++ +H   I LF++++N   WR  +T    L I +EL +CA+H       P +    P   +  +   + L +  +E  + ++++++ +MFLR YL+ R ++LHS V  ++S R +  +   +   +F LK L+  Y    L+V ++   L  +W +R+CE   +         +W IAITF+T+GYGD+ P + CG+ + + +GV GV  TA +VA++ + L L+  E ++H F++D  + K I+  A  +++  W L R  + +N +
Sbjct:   57 LRDRKFLLEDKRRLCAWALGAAMLGILLMIGHAELCP--AVYQPGSIYAIS--INGLISFSTGCLLILIIAFHYKDIRLFIIDHNQVDWRIAMTTNRVLGISLELLVCAVHPVASYLGPDVGVQVPVLKWNSSVTPICLCQSHRETWLEIELLLSGLMFLRLYLVHRAILLHSKVLLSASYRSIGSLNNINFTFRFVLKVLMNKYPARTLLVFIMLFWLSAAWMLRLCERQAEVETGDMGTALWLIAITFLTVGYGDVSPCTSCGKVVCLFTGVMGVACTAMLVAVVTKKLALNKGEKHVHFFMMDIQISKEIRNAAANVLRECWLLHRTTQAKNNN 389          
BLAST of Small conductance calcium-activated potassium channel protein 2 vs. Ensembl Cavefish
Match: kcnn1b (potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1b [Source:ZFIN;Acc:ZDB-GENE-060503-397])

HSP 1 Score: 148.673 bits (374), Expect = 7.251e-39
Identity = 128/416 (30.77%), Postives = 215/416 (51.68%), Query Frame = 1
Query:  220 QITRKSVGSTMSTRKCLHNNQKILSIFCLIFAAVGIGLMIIEIEIVSYNASNQISQLCFVCFFLKVLVSFFTGLLLICLVFYHRASILLFMVENNLNSWRFVITVRLSLSIFIELAICAIHAPPIP-NYNYVWTTYRLILGRPEKEDVPLDVIITIIMFLRGYLIFRVMVLHSHVYDNSSSRCVELMQGKSINSQFALKYLLTIYSKAFLIVSVICVILWTSWAVRVCEIYEKDSNLRFFNNIWFIAITFMTIGYGDIVPRSVCGRFIAVLSGVFGVMYTAYVVAIIAXXXXXXXXXXXXHQFVVDSDLDKSIKEQAVIIIQNFWRLKRAIK-TENYDTSDVFRWXXXXXXXXXXXXXXXXXXXQLETKSLRISTLYYSQ-------SQMQQEILQIKNQITNINELISYISNRLQ 1440
            Q   K +G  +  R+ L   +K LS + LIF   GI +M+ E E+ S+    + S   F    LK L+S  T +LL  ++ YH   I LFMV+N  + WR  +T    L I +EL +CAIH  PIP +Y + WT        P   D  +D+I++I MFLR YLI RVM+LHS ++ ++SSR +  +   + N++F +K L+TI     L+V  I   +  +W VRV   +   + L     +W + + F  +  G  VP      F+  L    G   TA VVA++A  L+L+ +E ++H F++D+ L K +K  A  +++  W + +  K  +  D + V + + K +++   L+  K E+ +L  ++  +  L  +Q       S++Q+   ++  +I  + E +  I++ LQ
Sbjct:   72 QKRNKDIGYKLGHRRALFEKRKRLSDYALIFGMFGIVVMVTETEL-SWGVYTKESSYSFA---LKCLISLSTLILLGLIIMYHAREIQLFMVDNGADDWRIAMTYERILFIVLELLVCAIH--PIPGHYVFTWTARLAFTYAPSVADADVDIILSIPMFLRLYLIGRVMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFSISSWIIAAWTVRVFLFWYPQNILPI--ALWLVYVIFSKLQTGSSVPFWKAVAFL--LQPFRGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLCKRVKNTAANVLRETWLIYKHTKLVKKIDHAKVRKHQRKFLQAIHQLRSVKMEQRKLNDQANTLVDLAKTQNVMYDLVSELQERSEELDKRIGQLEEKLDSITSSLQ 477          
BLAST of Small conductance calcium-activated potassium channel protein 2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000010066.1 (pep scaffold:Pmarinus_7.0:GL480376:18291:27660:1 gene:ENSPMAG00000009109.1 transcript:ENSPMAT00000010066.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 144.05 bits (362), Expect = 5.482e-41
Identity = 75/188 (39.89%), Postives = 117/188 (62.23%), Query Frame = 1
Query:  484 LFMVENNLNSWRFVITVRLSLSIFIELAICAIHAPPIP-NYNYVWTTYRLILGRPEKEDVPLDVIITIIMFLRGYLIFRVMVLHSHVYDNSSSRCVELMQGKSINSQFALKYLLTIYSKAFLIVSVICVILWTSWAVRVCEIYE--KDSNLRFFNNIWFIAITFMTIGYGDIVPRSVCGRFIAVLSGV 1038
            LF+V+N  + WR  +T +   +I +EL ICAIH  PIP NY ++WT           ++  +D++++I MFLR YLI RVM+LHS ++ ++SSR +  +   + N++F +K L+TI     L+V  I + +  +W VR CE Y   +D    F   +W I+ITF+TIGYGD+VP + CGR + +L+G+
Sbjct:    2 LFIVDNGADDWRIAMTYQRIFNIGLELLICAIH--PIPGNYTFMWTARLAFTYVSSVKEADVDIVLSIPMFLRLYLIARVMLLHSKLFTDASSRSIGALNKITFNTRFVMKTLMTICPGTVLLVFSISLWIIAAWTVRACERYHDPQDITSNFLAAMWLISITFLTIGYGDMVPHTYCGRGVCLLTGI 187          
BLAST of Small conductance calcium-activated potassium channel protein 2 vs. Ensembl Nematostella
Match: EDO46155 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RQS2])

HSP 1 Score: 49.6766 bits (117), Expect = 1.704e-6
Identity = 20/47 (42.55%), Postives = 31/47 (65.96%), Query Frame = 1
Query:  937 NNIWFIAITFMTIGYGDIVPRSVCGRFIAVLSGVFGVMYTAYVVAII 1077
             + W+I +T MT+GYGD+VPRS+ G+ I  +  V GV+  A  + I+
Sbjct:  327 ESFWYICVTLMTVGYGDVVPRSIAGKLIGSVCCVSGVVLLALPIPIL 373          
BLAST of Small conductance calcium-activated potassium channel protein 2 vs. Ensembl Nematostella
Match: EDO49636 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RFP0])

HSP 1 Score: 49.2914 bits (116), Expect = 3.084e-6
Identity = 27/92 (29.35%), Postives = 52/92 (56.52%), Query Frame = 1
Query:  937 NNIWFIAITFMTIGYGDIVPRSVCGRFIAVLSGVFGVMYTAYVVAIIAXXXXXXXXXXXXHQFVVDSDLDKSIKEQAVIIIQNFWRLKRAIK 1212
            + +W + +T  T+G+GDIVP SV  R +   + + G+   A  ++++ E LQL+  E  +  ++  +D  +   E+A   IQ+ WR ++ +K
Sbjct:  412 DTVWMMVVTMTTLGFGDIVPVSVVARGLVGFASILGIFLMALFISVVHEYLQLTNQEKRILAYIEKADHQQEKMEKAAACIQSCWRYRQFVK 503          
BLAST of Small conductance calcium-activated potassium channel protein 2 vs. Ensembl Medaka
Match: kcnn2 (small conductance calcium-activated potassium channel protein 2 [Source:NCBI gene;Acc:101174204])

HSP 1 Score: 211.075 bits (536), Expect = 9.917e-62
Identity = 122/330 (36.97%), Postives = 196/330 (59.39%), Query Frame = 1
Query:  232 KSVGSTMSTRKCLHNNQKILSIFCLIFAAVGIGLMIIEIEIVSYNASNQISQLCFVCFFLKVLVSFFTGLLLICLVFYHRASILLFMVENNLNSWRFVITVRLSLSIFIELAICAIHAPPIP-NYNYVWTTYRLILGRPEKEDVPLDVIITIIMFLRGYLIFRVMVLHSHVYDNSSSRCVELMQGKSINSQFALKYLLTIYSKAFLIVSVICVILWTSWAVRVCEIYEKDSNL--RFFNNIWFIAITFMTIGYGDIVPRSVCGRFIAVLSGVFGVMYTAYVVAIIAXXXXXXXXXXXXHQFVVDSDLDKSIKEQAVIIIQNFWRLKRAIK 1212
            +++G  +  R+ L   +K LS + LIF   GI +M+IE E+ S+ A  + S        LK L+S  T +LL  ++ YH   I LFMV+N  + WR  +T      I +E+ +CAIH  PIP NY + WT        P + D  +D+I++I MFLR YLI RVM+LHS ++ ++SSR +  +   + N++F +K L+TI     L+V  I + +  +W VR CE Y  + ++   F   +W I+ITF+TIGYGD+VP + CG+ + +L+G+ G   TA VVA++A+ L+L+ +E ++H F++D+ L K +K  A  +++  W + +  K
Sbjct:   65 QNIGEKLGHRRALFEKRKRLSDYALIFGMFGIVVMVIETEL-SWGAYGKES---LYSLALKCLISLSTIILLGLIIIYHAREIQLFMVDNAADDWRIAMTYERIFFICLEILVCAIH--PIPGNYTFTWTARLAYSYVPSRTDADVDIILSIPMFLRLYLIARVMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFTISLWIIAAWTVRACERYHDNQDITSNFLGAMWLISITFLTIGYGDMVPHTYCGKGVCLLTGIMGAGCTALVVAVVAKKLELTKAEKHVHNFMMDTQLTKRVKNTAANVLRETWLIYKNTK 388          
BLAST of Small conductance calcium-activated potassium channel protein 2 vs. Ensembl Medaka
Match: kcnn2 (small conductance calcium-activated potassium channel protein 2 [Source:NCBI gene;Acc:101174204])

HSP 1 Score: 210.69 bits (535), Expect = 1.924e-60
Identity = 121/323 (37.46%), Postives = 193/323 (59.75%), Query Frame = 1
Query:  232 KSVGSTMSTRKCLHNNQKILSIFCLIFAAVGIGLMIIEIEIVSYNASNQISQLCFVCFFLKVLVSFFTGLLLICLVFYHRASILLFMVENNLNSWRFVITVRLSLSIFIELAICAIHAPPIP-NYNYVWTTYRLILGRPEKEDVPLDVIITIIMFLRGYLIFRVMVLHSHVYDNSSSRCVELMQGKSINSQFALKYLLTIYSKAFLIVSVICVILWTSWAVRVCEIYEKDSNL--RFFNNIWFIAITFMTIGYGDIVPRSVCGRFIAVLSGVFGVMYTAYVVAIIAXXXXXXXXXXXXHQFVVDSDLDKSIKEQAVIIIQNFW 1191
            +++G  +  R+ L   +K LS + LIF   GI +M+IE E+ S+ A  + S        LK L+S  T +LL  ++ YH   I LFMV+N  + WR  +T      I +E+ +CAIH  PIP NY + WT        P + D  +D+I++I MFLR YLI RVM+LHS ++ ++SSR +  +   + N++F +K L+TI     L+V  I + +  +W VR CE Y  + ++   F   +W I+ITF+TIGYGD+VP + CG+ + +L+G+ G   TA VVA++A+ L+L+ +E ++H F++D+ L K +K  A  +++  W
Sbjct:  211 QNIGEKLGHRRALFEKRKRLSDYALIFGMFGIVVMVIETEL-SWGAYGKES---LYSLALKCLISLSTIILLGLIIIYHAREIQLFMVDNAADDWRIAMTYERIFFICLEILVCAIH--PIPGNYTFTWTARLAYSYVPSRTDADVDIILSIPMFLRLYLIARVMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFTISLWIIAAWTVRACERYHDNQDITSNFLGAMWLISITFLTIGYGDMVPHTYCGKGVCLLTGIMGAGCTALVVAVVAKKLELTKAEKHVHNFMMDTQLTKRVKNTAANVLRETW 527          
BLAST of Small conductance calcium-activated potassium channel protein 2 vs. Ensembl Medaka
Match: kcnn1a (small conductance calcium-activated potassium channel protein 2 [Source:NCBI gene;Acc:101164003])

HSP 1 Score: 208.379 bits (529), Expect = 5.903e-60
Identity = 121/327 (37.00%), Postives = 187/327 (57.19%), Query Frame = 1
Query:  220 QITRKSVGSTMSTRKCLHNNQKILSIFCLIFAAVGIGLMIIEIEIVSYNASNQISQLCFVCFFLKVLVSFFTGLLLICLVFYHRASILLFMVENNLNSWRFVITVRLSLSIFIELAICAIHAPPIPN-YNYVWTTYRLILGRPEKEDVPLDVIITIIMFLRGYLIFRVMVLHSHVYDNSSSRCVELMQGKSINSQFALKYLLTIYSKAFLIVSVICVILWTSWAVRVCEIYEKDSNL--RFFNNIWFIAITFMTIGYGDIVPRSVCGRFIAVLSGVFGVMYTAYVVAIIAXXXXXXXXXXXXHQFVVDSDLDKSIKEQAVIIIQNFW 1191
            Q   + +G  +  R+ L   +K LS + LIF   GI +M+ E E+ S+    + S   F    LK L+S  T +LL  ++ YH   I LFMV+N  + WR  +T      I +EL +CAIH  PIP  Y + WT        P   D  +D+I++I MFLR YLI RVM+LHS ++ ++SSR +  +   + N++F +K L+TI     L+V  I   +  +W VRVCE Y     +   F   +W I+ITF++IGYGD+VP + CG+ + +L+G+ G   TA VVA++A  L+L+ +E ++H F++D+ L K +K  A  +++  W
Sbjct:  142 QKKNRDIGYKLGHRRALFEKRKRLSDYALIFGMFGIVVMVTETEL-SWGVYTKESSYSFA---LKCLISLSTVILLGLIIMYHAREIQLFMVDNGADDWRIAMTYERIFFIVLELLVCAIH--PIPGQYVFTWTARLAFTYTPSVADADVDIILSIPMFLRLYLIGRVMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFSISSWIIAAWTVRVCERYHDKQEVTSNFLGAMWLISITFLSIGYGDMVPHTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLCKRVKNTAANVLRETW 462          
BLAST of Small conductance calcium-activated potassium channel protein 2 vs. Ensembl Medaka
Match: KCNN1 (small conductance calcium-activated potassium channel protein 3 [Source:NCBI gene;Acc:101154856])

HSP 1 Score: 199.904 bits (507), Expect = 1.306e-57
Identity = 118/328 (35.98%), Postives = 186/328 (56.71%), Query Frame = 1
Query:  220 QITRKSVGSTMSTRKCLHNNQKILSIFCLIFAAVGIGLMIIEIEIVSYNASNQISQLCFVCFFLKVLVSFFTGLLLICLVFYHRASILLFMVENNLNSWRFVITVRLSLSIFIELAICAIHAPPIPN-YNYVWTTYRLILGRPEKEDVPLDVIITIIMFLRGYLIFRVMVLHSHVYDNSSSRCVELMQGKSINSQFALKYLLTIYSKAFLIV-SVICVILWTSWAVRVCEIYEKDSNLR--FFNNIWFIAITFMTIGYGDIVPRSVCGRFIAVLSGVFGVMYTAYVVAIIAXXXXXXXXXXXXHQFVVDSDLDKSIKEQAVIIIQNFW 1191
            Q   K +   +  R+ L   +K LS + L+    GI +M++E E+     S + +      + LK L+S  T  LL  ++ YH   I LFMV+N  + WR  +T+   L I +EL +CAIH  PIP  Y + WT            D   D+I+++ MFLR YLI RVM+LHS ++ ++SSR +  +   + N++F +K L+TI     L+V SV C I+  +W VR+CE Y     +   F   +W ++ITF++IGYGD+VP + CG+ + +L+G+ G   TA VVA++A   +L+ +E ++H F++D+ L K IK  A  ++Q  W
Sbjct:   66 QKKTKDISYRLGLRRALFGKRKQLSDYALVCGMFGIIIMVVETELSRAFYSKEST----YSYTLKSLISVSTAFLLGLILMYHAREIQLFMVDNGADDWRIAMTLERILFIALELVVCAIH--PIPGQYVFSWTARLAFNYTSSPSDDDFDIILSVPMFLRLYLIGRVMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFSVTCWII-AAWIVRICERYHDTQEVTSTFLGAMWLVSITFLSIGYGDMVPHTYCGKGVCLLTGIMGAGCTALVVAVVARKSELTRAEKHVHNFMMDTQLLKKIKNTAANVLQETW 386          
BLAST of Small conductance calcium-activated potassium channel protein 2 vs. Ensembl Medaka
Match: KCNN1 (small conductance calcium-activated potassium channel protein 3 [Source:NCBI gene;Acc:101154856])

HSP 1 Score: 199.519 bits (506), Expect = 2.305e-57
Identity = 118/328 (35.98%), Postives = 186/328 (56.71%), Query Frame = 1
Query:  220 QITRKSVGSTMSTRKCLHNNQKILSIFCLIFAAVGIGLMIIEIEIVSYNASNQISQLCFVCFFLKVLVSFFTGLLLICLVFYHRASILLFMVENNLNSWRFVITVRLSLSIFIELAICAIHAPPIPN-YNYVWTTYRLILGRPEKEDVPLDVIITIIMFLRGYLIFRVMVLHSHVYDNSSSRCVELMQGKSINSQFALKYLLTIYSKAFLIV-SVICVILWTSWAVRVCEIYEKDSNLR--FFNNIWFIAITFMTIGYGDIVPRSVCGRFIAVLSGVFGVMYTAYVVAIIAXXXXXXXXXXXXHQFVVDSDLDKSIKEQAVIIIQNFW 1191
            Q   K +   +  R+ L   +K LS + L+    GI +M++E E+     S + +      + LK L+S  T  LL  ++ YH   I LFMV+N  + WR  +T+   L I +EL +CAIH  PIP  Y + WT            D   D+I+++ MFLR YLI RVM+LHS ++ ++SSR +  +   + N++F +K L+TI     L+V SV C I+  +W VR+CE Y     +   F   +W ++ITF++IGYGD+VP + CG+ + +L+G+ G   TA VVA++A   +L+ +E ++H F++D+ L K IK  A  ++Q  W
Sbjct:   68 QKKTKDISYRLGLRRALFGKRKQLSDYALVCGMFGIIIMVVETELSRAFYSKEST----YSYTLKSLISVSTAFLLGLILMYHAREIQLFMVDNGADDWRIAMTLERILFIALELVVCAIH--PIPGQYVFSWTARLAFNYTSSPSDDDFDIILSVPMFLRLYLIGRVMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFSVTCWII-AAWIVRICERYHDTQEVTSTFLGAMWLVSITFLSIGYGDMVPHTYCGKGVCLLTGIMGAGCTALVVAVVARKSELTRAEKHVHNFMMDTQLLKKIKNTAANVLQETW 388          
BLAST of Small conductance calcium-activated potassium channel protein 2 vs. Planmine SMEST
Match: SMESG000075601.1 (SMESG000075601.1)

HSP 1 Score: 555.829 bits (1431), Expect = 0.000e+0
Identity = 273/276 (98.91%), Postives = 274/276 (99.28%), Query Frame = 1
Query:  211 MELQITRKSVGSTMSTRKCLHNNQKILSIFCLIFAAVGIGLMIIEIEIVSYNASNQISQLCFVCFFLKVLVSFFTGLLLICLVFYHRASILLFMVENNLNSWRFVITVRLSLSIFIELAICAIHAPPIPNYNYVWTTYRLILGRPEKEDVPLDVIITIIMFLRGYLIFRVMVLHSHVYDNSSSRCVELMQGKSINSQFALKYLLTIYSKAFLIVSVICVILWTSWAVRVCEIYEKDSNLRFFNNIWFIAITFMTIGYGDIVPRSVCGRFIAVLSGV 1038
            MELQI RKSVGSTMSTRKCLHNNQKILSIFCLIFAAVGIGLMIIEIEIVSYNASNQISQLCFVCFFLKVLVSFFTGLLLICLVFYHRASILLFMVENNLNSWRFVITVRLSLSIFIELAICAIHAPPIPNYNYVWTTYRLILGRPEKEDVPLDVIITIIMFLRGYLIFRVMVLHSHVYD SSSRCVELMQGKSINSQFALKYLLTIYSKAFLIVSVICVILWTSWAVRVCEIYEKDSNLRFFNNIWFIAITFMTIGYGDIVPRSVCGRFIAVLSG+
Sbjct:    1 MELQIPRKSVGSTMSTRKCLHNNQKILSIFCLIFAAVGIGLMIIEIEIVSYNASNQISQLCFVCFFLKVLVSFFTGLLLICLVFYHRASILLFMVENNLNSWRFVITVRLSLSIFIELAICAIHAPPIPNYNYVWTTYRLILGRPEKEDVPLDVIITIIMFLRGYLIFRVMVLHSHVYDQSSSRCVELMQGKSINSQFALKYLLTIYSKAFLIVSVICVILWTSWAVRVCEIYEKDSNLRFFNNIWFIAITFMTIGYGDIVPRSVCGRFIAVLSGM 276          
BLAST of Small conductance calcium-activated potassium channel protein 2 vs. Planmine SMEST
Match: SMESG000075590.1 (SMESG000075590.1)

HSP 1 Score: 555.829 bits (1431), Expect = 0.000e+0
Identity = 273/276 (98.91%), Postives = 274/276 (99.28%), Query Frame = 1
Query:  211 MELQITRKSVGSTMSTRKCLHNNQKILSIFCLIFAAVGIGLMIIEIEIVSYNASNQISQLCFVCFFLKVLVSFFTGLLLICLVFYHRASILLFMVENNLNSWRFVITVRLSLSIFIELAICAIHAPPIPNYNYVWTTYRLILGRPEKEDVPLDVIITIIMFLRGYLIFRVMVLHSHVYDNSSSRCVELMQGKSINSQFALKYLLTIYSKAFLIVSVICVILWTSWAVRVCEIYEKDSNLRFFNNIWFIAITFMTIGYGDIVPRSVCGRFIAVLSGV 1038
            MELQI RKSVGSTMSTRKCLHNNQKILSIFCLIFAAVGIGLMIIEIEIVSYNASNQISQLCFVCFFLKVLVSFFTGLLLICLVFYHRASILLFMVENNLNSWRFVITVRLSLSIFIELAICAIHAPPIPNYNYVWTTYRLILGRPEKEDVPLDVIITIIMFLRGYLIFRVMVLHSHVYD SSSRCVELMQGKSINSQFALKYLLTIYSKAFLIVSVICVILWTSWAVRVCEIYEKDSNLRFFNNIWFIAITFMTIGYGDIVPRSVCGRFIAVLSG+
Sbjct:    1 MELQIPRKSVGSTMSTRKCLHNNQKILSIFCLIFAAVGIGLMIIEIEIVSYNASNQISQLCFVCFFLKVLVSFFTGLLLICLVFYHRASILLFMVENNLNSWRFVITVRLSLSIFIELAICAIHAPPIPNYNYVWTTYRLILGRPEKEDVPLDVIITIIMFLRGYLIFRVMVLHSHVYDQSSSRCVELMQGKSINSQFALKYLLTIYSKAFLIVSVICVILWTSWAVRVCEIYEKDSNLRFFNNIWFIAITFMTIGYGDIVPRSVCGRFIAVLSGM 276          
BLAST of Small conductance calcium-activated potassium channel protein 2 vs. Planmine SMEST
Match: SMESG000060715.1 (SMESG000060715.1)

HSP 1 Score: 215.698 bits (548), Expect = 9.563e-65
Identity = 131/341 (38.42%), Postives = 210/341 (61.58%), Query Frame = 1
Query:  232 KSVGSTMSTRKCLHNNQKILSIFCLIFAAVGIGLMIIEIEIVSY-NASNQISQLCFVCFFLKVLVSFFTGLLLICLVFYHRASILLFMVENNLNSWRFVITVRLSLSIFIELAICAIHAPPIPNYNYVWTTYRLILGRPEKED--VPLDVIITIIMFLRGYLIFRVMVLHSHVYDNSSSRCVELMQGKSINSQFALKYLLTIYSKAFLIVSVICVILWTSWAVRVCEIYEKDSNLRFFNNIWFIAITFMTIGYGDIVPRSVCGRFIAVLSGVFGVMYTAYVVAIIAXXXXXXXXXXXXHQFVVDSDLDKSIKEQAVIIIQNFWRL---------KRAIKTE 1218
            K+VG+ ++ RK L   +K +S  CLIF+  GI LMI  IE+  +    NQ S + F    LK+ +SF T +LL+ L++YH   I LFM++N +  WR  +++   L I +EL IC IH  P P  + +     L  G        VP+DV++++ MFLR +++ RV++LHS +Y ++S++ +  +     N  F  K L+++Y++  L   +  + LW SWA+R CE Y+ D++L FF+++W IAITF+T+GYGD+VP+S CG+ I+V++G+FGV  TA VVA++A  L+LS +E Y+H FV+  +L K +K  A  +++  W +         +RA+K E
Sbjct:   29 KNVGARLAKRKLLFKKRKNVSDLCLIFSMFGILLMITYIELSIFLMKGNQKSNI-FSAMILKLFISFTTFMLLLFLIWYHSIDIQLFMIDNGMEDWRLAMSLSRILVIGLELLICLIH--PFPGSHNLKIVNLLKKGSNNISISIVPIDVLLSLPMFLRFFMVCRVLMLHSQLYQDASAQSLGALNRIHFNFAFIFKSLMSLYAEYVLTAMITFLFLWASWAIRACESYQGDNHLDFFDSMWIIAITFLTVGYGDMVPQSTCGKAISVMTGIFGVGCTALVVAVLARKLELSRAEMYVHNFVISVELSKQLKHAAANVVKEGWLVHKYKKLGWKQRALKHE 366          
BLAST of Small conductance calcium-activated potassium channel protein 2 vs. Planmine SMEST
Match: SMESG000063214.1 (SMESG000063214.1)

HSP 1 Score: 190.66 bits (483), Expect = 3.215e-53
Identity = 133/415 (32.05%), Postives = 233/415 (56.14%), Query Frame = 1
Query:  232 KSVGSTMSTRKCLHNNQKILSIFCLIFAAVGIGLMIIEIEIVSYNASNQISQLCFVCFFLKVLVSFFTGLLLICLVFYHRASILLFMVENNLNSWRFVITVRLSLSIFIELAICAIHAPPIP-NYNYVWTTYRLILGRPEKED--VPLDVIITIIMFLRGYLIFRVMVLHSHVYDNSSSRCVELMQGKSINSQFALKYLLTIYSKAFLIVSVICVILWTSWAVRVCEIYEKDSNLRFFNNIWFIAITFMTIGYGDIVPRSVCGRFIAVLSGVFGVMYTAYVVAIIAXXXXXXXXXXXXHQFVVDSDLDKSIKEQAVIIIQNFWRLKRAIK-TENYDTSDVFRWXXXXXXXXXXXXXXXXXXXQLETKSLRISTLYYSQS-------QMQQEILQIKNQITNINELISYISNRLQK 1443
            K+VG  +  RK L   +K +S F + FA  GI +M+IE+E+   +      +  F  +FLK L+   T +L+  +VFYH   + +  +++++  WR  +++R    + +E+ ICAIH  P P N  + W+ Y  + G+ +  D  V  D+I+ I MF R YL +R M+LHS +  +  SR +  M   + +  F +K ++T+Y    L V ++ VIL +SW +  CE      +   FN+IW I ITF++IGYGD+ P +VCGR +++ +G+ G   TA VVA+ A+ L+L+ +E ++  F++++ L K++K  A  +++  W L +  K TEN +   +++ + K +++   L+  K+E  +LE +S +   L  +         Q+ QE LQIKN I  + + I  + N+ ++
Sbjct:  264 KTVGFRLGKRKTLLEQRKKISDFSVGFALFGIVVMVIELELC--DNMKLYEKKDFYSYFLKSLIGLSTLMLIGLIVFYHFIEVKILSLDDSIEDWRLTLSLRRIFQLILEILICAIH--PFPGNILFKWSIY--LAGKKQISDRLVSFDIILGICMFSRLYLFYRSMLLHSRLLSDVGSRSIGAMNKVNFDISFLIKTMMTLYPVRVLFVFILTVILISSWILHTCENAYDSFHADMFNSIWLICITFLSIGYGDVFPHTVCGRIVSISNGLMGCACTALVVAVFAKRLELTKAERHVMDFMMENQLSKNLKYYAANVLRETWLLYKYTKLTENVNIMKIWKHQRKFLRAIYGLRKMKSELRKLEDESNQTGYLIQAHHRSYLLLVQVCQEQLQIKNNILLLEDKIIQLQNQTKE 672          
BLAST of Small conductance calcium-activated potassium channel protein 2 vs. Planmine SMEST
Match: SMESG000063214.1 (SMESG000063214.1)

HSP 1 Score: 190.66 bits (483), Expect = 3.339e-53
Identity = 133/415 (32.05%), Postives = 233/415 (56.14%), Query Frame = 1
Query:  232 KSVGSTMSTRKCLHNNQKILSIFCLIFAAVGIGLMIIEIEIVSYNASNQISQLCFVCFFLKVLVSFFTGLLLICLVFYHRASILLFMVENNLNSWRFVITVRLSLSIFIELAICAIHAPPIP-NYNYVWTTYRLILGRPEKED--VPLDVIITIIMFLRGYLIFRVMVLHSHVYDNSSSRCVELMQGKSINSQFALKYLLTIYSKAFLIVSVICVILWTSWAVRVCEIYEKDSNLRFFNNIWFIAITFMTIGYGDIVPRSVCGRFIAVLSGVFGVMYTAYVVAIIAXXXXXXXXXXXXHQFVVDSDLDKSIKEQAVIIIQNFWRLKRAIK-TENYDTSDVFRWXXXXXXXXXXXXXXXXXXXQLETKSLRISTLYYSQS-------QMQQEILQIKNQITNINELISYISNRLQK 1443
            K+VG  +  RK L   +K +S F + FA  GI +M+IE+E+   +      +  F  +FLK L+   T +L+  +VFYH   + +  +++++  WR  +++R    + +E+ ICAIH  P P N  + W+ Y  + G+ +  D  V  D+I+ I MF R YL +R M+LHS +  +  SR +  M   + +  F +K ++T+Y    L V ++ VIL +SW +  CE      +   FN+IW I ITF++IGYGD+ P +VCGR +++ +G+ G   TA VVA+ A+ L+L+ +E ++  F++++ L K++K  A  +++  W L +  K TEN +   +++ + K +++   L+  K+E  +LE +S +   L  +         Q+ QE LQIKN I  + + I  + N+ ++
Sbjct:  263 KTVGFRLGKRKTLLEQRKKISDFSVGFALFGIVVMVIELELC--DNMKLYEKKDFYSYFLKSLIGLSTLMLIGLIVFYHFIEVKILSLDDSIEDWRLTLSLRRIFQLILEILICAIH--PFPGNILFKWSIY--LAGKKQISDRLVSFDIILGICMFSRLYLFYRSMLLHSRLLSDVGSRSIGAMNKVNFDISFLIKTMMTLYPVRVLFVFILTVILISSWILHTCENAYDSFHADMFNSIWLICITFLSIGYGDVFPHTVCGRIVSISNGLMGCACTALVVAVFAKRLELTKAERHVMDFMMENQLSKNLKYYAANVLRETWLLYKYTKLTENVNIMKIWKHQRKFLRAIYGLRKMKSELRKLEDESNQTGYLIQAHHRSYLLLVQVCQEQLQIKNNILLLEDKIIQLQNQTKE 671          
The following BLAST results are available for this feature:
BLAST of Small conductance calcium-activated potassium channel protein 2 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
KCNN16.418e-6237.27potassium calcium-activated channel subfamily N me... [more]
KCNN17.348e-6237.27potassium calcium-activated channel subfamily N me... [more]
KCNN26.326e-6136.67potassium calcium-activated channel subfamily N me... [more]
KCNN28.829e-6137.15potassium calcium-activated channel subfamily N me... [more]
KCNN23.272e-5937.15potassium calcium-activated channel subfamily N me... [more]
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BLAST of Small conductance calcium-activated potassium channel protein 2 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
kcnl-21.296e-4333.33KCNN (Potassium K ChaNNel, calcium activated)-Like... [more]
kcnl-21.683e-4333.33KCNN (Potassium K ChaNNel, calcium activated)-Like... [more]
kcnl-21.731e-4333.33KCNN (Potassium K ChaNNel, calcium activated)-Like... [more]
kcnl-21.767e-4333.33KCNN (Potassium K ChaNNel, calcium activated)-Like... [more]
kcnl-22.028e-4333.33KCNN (Potassium K ChaNNel, calcium activated)-Like... [more]
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BLAST of Small conductance calcium-activated potassium channel protein 2 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
SK1.622e-5837.20gene:FBgn0029761 transcript:FBtr0300467[more]
SK5.464e-5836.81gene:FBgn0029761 transcript:FBtr0301949[more]
SK3.563e-5736.81gene:FBgn0029761 transcript:FBtr0301952[more]
SK6.212e-5737.42gene:FBgn0029761 transcript:FBtr0301953[more]
SK8.763e-5736.81gene:FBgn0029761 transcript:FBtr0301954[more]
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BLAST of Small conductance calcium-activated potassium channel protein 2 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
kcnn28.225e-6237.77potassium calcium-activated channel subfamily N me... [more]
kcnn1a1.405e-6037.31potassium intermediate/small conductance calcium-a... [more]
kcnn1b5.181e-6038.15potassium intermediate/small conductance calcium-a... [more]
kcnn1b5.467e-6038.15potassium intermediate/small conductance calcium-a... [more]
kcnn1b6.205e-5937.34potassium intermediate/small conductance calcium-a... [more]
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BLAST of Small conductance calcium-activated potassium channel protein 2 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
wdr171.059e-6036.70WD repeat domain 17 [Source:Xenbase;Acc:XB-GENE-10... [more]
wdr171.255e-6036.70WD repeat domain 17 [Source:Xenbase;Acc:XB-GENE-10... [more]
wdr171.576e-6036.70WD repeat domain 17 [Source:Xenbase;Acc:XB-GENE-10... [more]
wdr174.657e-6036.70WD repeat domain 17 [Source:Xenbase;Acc:XB-GENE-10... [more]
KCNN25.989e-6037.15potassium channel, calcium activated intermediate/... [more]
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BLAST of Small conductance calcium-activated potassium channel protein 2 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Kcnn24.285e-6136.67potassium intermediate/small conductance calcium-a... [more]
Kcnn24.285e-6136.67potassium intermediate/small conductance calcium-a... [more]
Kcnn33.656e-5935.48potassium intermediate/small conductance calcium-a... [more]
Kcnn24.952e-5936.67potassium intermediate/small conductance calcium-a... [more]
Kcnn16.176e-5937.46potassium intermediate/small conductance calcium-a... [more]
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BLAST of Small conductance calcium-activated potassium channel protein 2 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q92952|KCNN1_HUMAN3.529e-6137.27Small conductance calcium-activated potassium chan... [more]
sp|Q9H2S1|KCNN2_HUMAN3.038e-6036.67Small conductance calcium-activated potassium chan... [more]
sp|P70604|KCNN2_RAT3.399e-6036.67Small conductance calcium-activated potassium chan... [more]
sp|P70606|KCNN1_RAT8.309e-5937.77Small conductance calcium-activated potassium chan... [more]
sp|P58391|KCNN3_MOUSE2.557e-5835.48Small conductance calcium-activated potassium chan... [more]
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BLAST of Small conductance calcium-activated potassium channel protein 2 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A1I8FZC76.390e-6734.22CaMBD domain-containing protein OS=Macrostomum lig... [more]
V4B5G35.598e-6637.20CaMBD domain-containing protein OS=Lottia gigantea... [more]
A0A267GF912.759e-6534.21CaMBD domain-containing protein OS=Macrostomum lig... [more]
A0A1W0WAE12.115e-6337.65Small conductance calcium-activated potassium chan... [more]
A0A1D1W8A93.277e-6238.89CaMBD domain-containing protein OS=Ramazzottius va... [more]
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BLAST of Small conductance calcium-activated potassium channel protein 2 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 4
Match NameE-valueIdentityDescription
kcnn22.941e-6037.15potassium calcium-activated channel subfamily N me... [more]
kcnn36.536e-5735.38potassium intermediate/small conductance calcium-a... [more]
kcnn41.473e-3929.97potassium calcium-activated channel subfamily N me... [more]
kcnn1b7.251e-3930.77potassium intermediate/small conductance calcium-a... [more]
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BLAST of Small conductance calcium-activated potassium channel protein 2 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1
Match NameE-valueIdentityDescription
ENSPMAT00000010066.15.482e-4139.89pep scaffold:Pmarinus_7.0:GL480376:18291:27660:1 g... [more]
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BLAST of Small conductance calcium-activated potassium channel protein 2 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Small conductance calcium-activated potassium channel protein 2 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 2
Match NameE-valueIdentityDescription
EDO461551.704e-642.55Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO496363.084e-629.35Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Small conductance calcium-activated potassium channel protein 2 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
kcnn29.917e-6236.97small conductance calcium-activated potassium chan... [more]
kcnn21.924e-6037.46small conductance calcium-activated potassium chan... [more]
kcnn1a5.903e-6037.00small conductance calcium-activated potassium chan... [more]
KCNN11.306e-5735.98small conductance calcium-activated potassium chan... [more]
KCNN12.305e-5735.98small conductance calcium-activated potassium chan... [more]
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BLAST of Small conductance calcium-activated potassium channel protein 2 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000075601.10.000e+098.91SMESG000075601.1[more]
SMESG000075590.10.000e+098.91SMESG000075590.1[more]
SMESG000060715.19.563e-6538.42SMESG000060715.1[more]
SMESG000063214.13.215e-5332.05SMESG000063214.1[more]
SMESG000063214.13.339e-5332.05SMESG000063214.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30018278 ID=SMED30018278|Name=Small conductance calcium-activated potassium channel protein 2|organism=Schmidtea mediterranea sexual|type=transcript|length=1463bp
TCTATTATTCGCTAAAATAGCAACATGTGCAAATTGTTGTCTGGTTACAA
GTGCTGAAAGAAACAGCTGTTGAAATAAAGAATTTCCTGTTGAAAGAAAT
CCAAGAAATCAATAAATTGCTGCGTTAACTTTGAGTTAGATTTTCTCGAA
AACAAATCTGCTTGTAGGTGGAATTTTTGTTGACATTTTTCTTTGTTTAC
ATATTTTGAAATGGAACTTCAAATTACCAGGAAATCAGTGGGTTCAACGA
TGTCGACACGAAAATGTTTGCATAACAATCAGAAAATTTTGAGTATATTC
TGTTTGATCTTTGCAGCAGTTGGAATCGGTTTAATGATCATCGAGATTGA
AATCGTTTCATACAATGCAAGCAATCAGATCTCTCAGCTTTGCTTCGTAT
GTTTCTTTTTGAAGGTTCTCGTCTCCTTCTTTACTGGATTATTGTTGATC
TGTTTGGTTTTTTATCACAGAGCGAGTATTTTGTTGTTTATGGTGGAGAA
TAATTTGAACAGTTGGCGGTTCGTTATCACTGTCCGATTGTCTCTGTCGA
TTTTCATTGAGCTTGCAATATGCGCTATTCATGCTCCGCCGATTCCGAAT
TACAACTATGTTTGGACGACTTATCGGTTGATTCTTGGCCGACCAGAGAA
AGAGGATGTGCCACTTGATGTTATTATTACTATCATAATGTTTCTTCGTG
GATATTTGATTTTTCGAGTTATGGTTCTACATAGTCACGTTTATGATAAC
AGTTCAAGTCGATGTGTTGAACTGATGCAAGGAAAGTCCATCAACAGCCA
ATTTGCTTTGAAATATCTGTTGACAATTTATTCAAAGGCATTTCTTATTG
TATCCGTAATCTGTGTAATTCTATGGACAAGTTGGGCTGTGAGGGTTTGT
GAAATTTATGAAAAAGATTCAAATTTGCGATTCTTTAATAACATATGGTT
CATAGCCATTACGTTCATGACAATTGGATACGGTGATATTGTTCCTAGGT
CAGTTTGTGGGAGATTCATTGCTGTGCTGTCGGGAGTGTTTGGAGTTATG
TACACTGCATATGTTGTGGCAATTATTGCAGAAAGCTTACAGTTATCATA
TTCGGAGTCTTATCTCCATCAATTCGTAGTCGACAGTGATCTAGACAAAA
GTATAAAGGAGCAAGCTGTTATAATTATTCAAAATTTTTGGCGTCTCAAA
AGAGCAATAAAAACCGAAAATTATGACACTTCTGATGTTTTTCGATGGAA
GCTAAAATTAATTAAAAGTAAAAAAAATTTGAAAATTTTTAAAAATGAAA
AAATACAGCTTGAAACCAAGTCACTGAGAATTTCCACACTTTACTACAGT
CAAAGTCAAATGCAGCAAGAAATTCTCCAAATCAAGAATCAAATTACCAA
CATAAATGAATTAATTTCCTATATTTCAAATCGACTTCAAAAGTGATTGA
AAGTTTTCCTGAA
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protein sequence of SMED30018278-orf-1

>SMED30018278-orf-1 ID=SMED30018278-orf-1|Name=SMED30018278-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=412bp
MELQITRKSVGSTMSTRKCLHNNQKILSIFCLIFAAVGIGLMIIEIEIVS
YNASNQISQLCFVCFFLKVLVSFFTGLLLICLVFYHRASILLFMVENNLN
SWRFVITVRLSLSIFIELAICAIHAPPIPNYNYVWTTYRLILGRPEKEDV
PLDVIITIIMFLRGYLIFRVMVLHSHVYDNSSSRCVELMQGKSINSQFAL
KYLLTIYSKAFLIVSVICVILWTSWAVRVCEIYEKDSNLRFFNNIWFIAI
TFMTIGYGDIVPRSVCGRFIAVLSGVFGVMYTAYVVAIIAESLQLSYSES
YLHQFVVDSDLDKSIKEQAVIIIQNFWRLKRAIKTENYDTSDVFRWKLKL
IKSKKNLKIFKNEKIQLETKSLRISTLYYSQSQMQQEILQIKNQITNINE
LISYISNRLQK*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000418head
PLANA:0003117parapharyngeal cell
Vocabulary: INTERPRO
TermDefinition
IPR013099K_chnl_dom
IPR015449K_chnl_Ca-activ_SK
Vocabulary: biological process
TermDefinition
GO:0006813potassium ion transport
GO:0006810transport
GO:0006811ion transport
GO:0048168regulation of neuronal synaptic plasticity
GO:0071805potassium ion transmembrane transport
Vocabulary: cellular component
TermDefinition
GO:0016021integral component of membrane
GO:0005886plasma membrane
GO:0016020membrane
GO:0043025neuronal cell body
GO:0043197dendritic spine
Vocabulary: molecular function
TermDefinition
GO:0016286small conductance calcium-activated potassium channel activity
GO:0005515protein binding
GO:0005516calmodulin binding
GO:0015269calcium-activated potassium channel activity
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableGENE3DG3DSA:1.10.287.70coord: 292..388
e-value: 1.5E-5
score: 26.9
NoneNo IPR availableGENE3DG3DSA:1.10.287.70coord: 193..291
e-value: 2.3E-16
score: 61.6
NoneNo IPR availableSUPERFAMILYSSF81324Voltage-gated potassium channelscoord: 202..329
NoneNo IPR availableTMHMMTMhelixcoord: 202..224
NoneNo IPR availableTMHMMTMhelixcoord: 106..128
NoneNo IPR availableTMHMMTMhelixcoord: 239..261
NoneNo IPR availableTMHMMTMhelixcoord: 154..173
NoneNo IPR availableTMHMMTMhelixcoord: 268..290
NoneNo IPR availableTMHMMTMhelixcoord: 63..85
NoneNo IPR availableTMHMMTMhelixcoord: 26..48
IPR013099Potassium channel domainPFAMPF07885Ion_trans_2coord: 217..293
e-value: 2.6E-15
score: 56.2
IPR015449Potassium channel, calcium-activated, SKPFAMPF03530SK_channelcoord: 15..128
e-value: 1.4E-25
score: 89.5
IPR015449Potassium channel, calcium-activated, SKPANTHERPTHR10153SMALL CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNELcoord: 7..410