Cathepsin L2
Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30018252 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 28Note: Hover over icons to view figure legend
Homology
BLAST of Cathepsin L2 vs. Ensembl Human
Match: CTSL (cathepsin L [Source:HGNC Symbol;Acc:HGNC:2537]) HSP 1 Score: 334.339 bits (856), Expect = 4.046e-113 Identity = 169/317 (53.31%), Postives = 211/317 (66.56%), Query Frame = 3 Query: 117 FTINSELNDEWEAYKTQFGKKYVSLNEISRRLIWEQNLKYIQQHNLEHDLGKHTYTLGLNHFADMTNEEFRANYLGVSPKRMNFTSHFIAPENVGALPSSVDWRTKGFVTPVKNQQQCGSCWSFSTTGSLEGQHYRKTQNLISFSEQQLVDCSGSFGNNGCDGGLMDSAFQYIQQY-GIEAESTYPYTAQDGNCVYDKSKVVGSCTGFSDIPHGNEQALASAVATVGPISVAIDASNYSFQLYKSGIYNEPQCSSSQLDHGVLAIGYGTE----NGKNFWLVKNSWGIGWGIQGYIKMSKDQGNQCGISTMASYPLV 1052 T + L +W +K + Y E RR +WE+N+K I+ HN E+ GKH++T+ +N F DMT+EEFR G ++ F P A P SVDWR KG+VTPVKNQ QCGSCW+FS TG+LEGQ +RKT LIS SEQ LVDCSG GN GC+GGLMD AFQY+Q G+++E +YPY A + +C Y+ V + TGF DIP E+AL AVATVGPISVAIDA + SF YK GIY EP CSS +DHGVL +GYG E + +WLVKNSWG WG+ GY+KM+KD+ N CGI++ ASYP V Sbjct: 19 LTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIELHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEA-PRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPK-QEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV 333
BLAST of Cathepsin L2 vs. Ensembl Human
Match: CTSL (cathepsin L [Source:HGNC Symbol;Acc:HGNC:2537]) HSP 1 Score: 334.339 bits (856), Expect = 4.046e-113 Identity = 169/317 (53.31%), Postives = 211/317 (66.56%), Query Frame = 3 Query: 117 FTINSELNDEWEAYKTQFGKKYVSLNEISRRLIWEQNLKYIQQHNLEHDLGKHTYTLGLNHFADMTNEEFRANYLGVSPKRMNFTSHFIAPENVGALPSSVDWRTKGFVTPVKNQQQCGSCWSFSTTGSLEGQHYRKTQNLISFSEQQLVDCSGSFGNNGCDGGLMDSAFQYIQQY-GIEAESTYPYTAQDGNCVYDKSKVVGSCTGFSDIPHGNEQALASAVATVGPISVAIDASNYSFQLYKSGIYNEPQCSSSQLDHGVLAIGYGTE----NGKNFWLVKNSWGIGWGIQGYIKMSKDQGNQCGISTMASYPLV 1052 T + L +W +K + Y E RR +WE+N+K I+ HN E+ GKH++T+ +N F DMT+EEFR G ++ F P A P SVDWR KG+VTPVKNQ QCGSCW+FS TG+LEGQ +RKT LIS SEQ LVDCSG GN GC+GGLMD AFQY+Q G+++E +YPY A + +C Y+ V + TGF DIP E+AL AVATVGPISVAIDA + SF YK GIY EP CSS +DHGVL +GYG E + +WLVKNSWG WG+ GY+KM+KD+ N CGI++ ASYP V Sbjct: 19 LTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIELHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEA-PRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPK-QEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV 333
BLAST of Cathepsin L2 vs. Ensembl Human
Match: CTSV (cathepsin V [Source:HGNC Symbol;Acc:HGNC:2538]) HSP 1 Score: 329.331 bits (843), Expect = 3.517e-111 Identity = 165/315 (52.38%), Postives = 209/315 (66.35%), Query Frame = 3 Query: 123 INSELNDEWEAYKTQFGKKYVSLNEISRRLIWEQNLKYIQQHNLEHDLGKHTYTLGLNHFADMTNEEFRANYLGVSPKRMNFTSHFIAPENVGALPSSVDWRTKGFVTPVKNQQQCGSCWSFSTTGSLEGQHYRKTQNLISFSEQQLVDCSGSFGNNGCDGGLMDSAFQYIQQY-GIEAESTYPYTAQDGNCVYDKSKVVGSCTGFSDIPHGNEQALASAVATVGPISVAIDASNYSFQLYKSGIYNEPQCSSSQLDHGVLAIGYGTE----NGKNFWLVKNSWGIGWGIQGYIKMSKDQGNQCGISTMASYPLV 1052 + L+ +W +K + Y + E RR +WE+N+K I+ HN E+ GKH +T+ +N F DMTNEEFR ++ F P + LP SVDWR KG+VTPVKNQ+QCGSCW+FS TG+LEGQ +RKT L+S SEQ LVDCS GN GC+GG M AFQY+++ G+++E +YPY A D C Y V + TGF+ + G E+AL AVATVGPISVA+DA + SFQ YKSGIY EP CSS LDHGVL +GYG E N +WLVKNSWG WG GY+K++KD+ N CGI+T ASYP V Sbjct: 21 FDQNLDTKWYQWKATHRRLYGANEEGWRRAVWEKNMKMIELHNGEYSQGKHGFTMAMNAFGDMTNEEFRQMMGCFRNQKFRKGKVFREPLFLD-LPKSVDWRKKGYVTPVKNQKQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQGNQGCNGGFMARAFQYVKENGGLDSEESYPYVAVDEICKYRPENSVANDTGFTVVAPGKEKALMKAVATVGPISVAMDAGHSSFQFYKSGIYFEPDCSSKNLDHGVLVVGYGFEGANSNNSKYWLVKNSWGPEWGSNGYVKIAKDKNNHCGIATAASYPNV 334
BLAST of Cathepsin L2 vs. Ensembl Human
Match: CTSV (cathepsin V [Source:HGNC Symbol;Acc:HGNC:2538]) HSP 1 Score: 329.331 bits (843), Expect = 3.517e-111 Identity = 165/315 (52.38%), Postives = 209/315 (66.35%), Query Frame = 3 Query: 123 INSELNDEWEAYKTQFGKKYVSLNEISRRLIWEQNLKYIQQHNLEHDLGKHTYTLGLNHFADMTNEEFRANYLGVSPKRMNFTSHFIAPENVGALPSSVDWRTKGFVTPVKNQQQCGSCWSFSTTGSLEGQHYRKTQNLISFSEQQLVDCSGSFGNNGCDGGLMDSAFQYIQQY-GIEAESTYPYTAQDGNCVYDKSKVVGSCTGFSDIPHGNEQALASAVATVGPISVAIDASNYSFQLYKSGIYNEPQCSSSQLDHGVLAIGYGTE----NGKNFWLVKNSWGIGWGIQGYIKMSKDQGNQCGISTMASYPLV 1052 + L+ +W +K + Y + E RR +WE+N+K I+ HN E+ GKH +T+ +N F DMTNEEFR ++ F P + LP SVDWR KG+VTPVKNQ+QCGSCW+FS TG+LEGQ +RKT L+S SEQ LVDCS GN GC+GG M AFQY+++ G+++E +YPY A D C Y V + TGF+ + G E+AL AVATVGPISVA+DA + SFQ YKSGIY EP CSS LDHGVL +GYG E N +WLVKNSWG WG GY+K++KD+ N CGI+T ASYP V Sbjct: 21 FDQNLDTKWYQWKATHRRLYGANEEGWRRAVWEKNMKMIELHNGEYSQGKHGFTMAMNAFGDMTNEEFRQMMGCFRNQKFRKGKVFREPLFLD-LPKSVDWRKKGYVTPVKNQKQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQGNQGCNGGFMARAFQYVKENGGLDSEESYPYVAVDEICKYRPENSVANDTGFTVVAPGKEKALMKAVATVGPISVAMDAGHSSFQFYKSGIYFEPDCSSKNLDHGVLVVGYGFEGANSNNSKYWLVKNSWGPEWGSNGYVKIAKDKNNHCGIATAASYPNV 334
BLAST of Cathepsin L2 vs. Ensembl Human
Match: CTSK (cathepsin K [Source:HGNC Symbol;Acc:HGNC:2536]) HSP 1 Score: 321.242 bits (822), Expect = 4.527e-108 Identity = 159/310 (51.29%), Postives = 209/310 (67.42%), Query Frame = 3 Query: 135 LNDEWEAYKTQFGKKYVS-LNEISRRLIWEQNLKYIQQHNLEHDLGKHTYTLGLNHFADMTNEEFRANYLGV----SPKRMNFTSHFIAPENVGALPSSVDWRTKGFVTPVKNQQQCGSCWSFSTTGSLEGQHYRKTQNLISFSEQQLVDCSGSFGNNGCDGGLMDSAFQYIQQ-YGIEAESTYPYTAQDGNCVYDKSKVVGSCTGFSDIPHGNEQALASAVATVGPISVAIDASNYSFQLYKSGIYNEPQCSSSQLDHGVLAIGYGTENGKNFWLVKNSWGIGWGIQGYIKMSKDQGNQCGISTMASYP 1046 L+ WE +K K+Y + ++EISRRLIWE+NLKYI HNLE LG HTY L +NH DMT+EE G+ S R N T + PE G P SVD+R KG+VTPVKNQ QCGSCW+FS+ G+LEGQ +KT L++ S Q LVDC N+GC GG M +AFQY+Q+ GI++E YPY Q+ +C+Y+ + C G+ +IP GNE+AL AVA VGP+SVAIDAS SFQ Y G+Y + C+S L+H VLA+GYG + G W++KNSWG WG +GYI M++++ N CGI+ +AS+P Sbjct: 22 LDTHWELWKKTHRKQYNNKVDEISRRLIWEKNLKYISIHNLEASLGVHTYELAMNHLGDMTSEEVVQKMTGLKVPLSHSRSNDTLYI--PEWEGRAPDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSE--NDGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYILMARNKNNACGIANLASFP 327
BLAST of Cathepsin L2 vs. Ensembl Celegans
Match: cpl-1 (CathePsin L family [Source:UniProtKB/TrEMBL;Acc:H9G333]) HSP 1 Score: 317.39 bits (812), Expect = 6.421e-107 Identity = 154/312 (49.36%), Postives = 213/312 (68.27%), Query Frame = 3 Query: 141 DEWEAYKTQFGKKYVSLNEISRRLIWEQNLKYIQQHNLEHDLGKHTYTLGLNHFADMTNEEFRA-----NYLGVSPKRMNFTSHFIAPENVGALPSSVDWRTKGFVTPVKNQQQCGSCWSFSTTGSLEGQHYRKTQNLISFSEQQLVDCSGSFGNNGCDGGLMDSAFQYIQQ-YGIEAESTYPYTAQDGNCVYDKSKVVGSCTGFSDIPHGNEQALASAVATVGPISVAIDASNYSFQLYKSGIYNEPQCSSSQLDHGVLAIGYGT--ENGKNFWLVKNSWGIGWGIQGYIKMSKDQGNQCGISTMASYPLV 1052 ++W+ YK F K+Y E + + +N+ +I+ HN +H LG+ T+ +GLNH AD+ ++R G S R+ +S F+AP NV +P VDWR VT VKNQ CGSCW+FS TG+LEGQH RK L+S SEQ LVDCS +GN+GC+GGLMD AF+YI+ +G++ E +YPY +D C ++K V G+ D P G+E+ L AVAT GPIS+AIDA + SFQLYK G+Y + +CSS +LDHGVL +GYGT E+G ++W+VKNSWG GWG +GYI++++++ N CG++T ASYPLV Sbjct: 30 EKWDDYKEDFDKEYSESEEQTYMEAFVKNMIHIENHNRDHRLGRKTFEMGLNHIADLPFSQYRKLNGYRRLFGDS--RIKNSSSFLAPFNV-QVPDEVDWRDTHLVTDVKNQGMCGSCWAFSATGALEGQHARKLGQLVSLSEQNLVDCSTKYGNHGCNGGLMDQAFEYIRDNHGVDTEESYPYKGRDMKCHFNKKTVGADDKGYVDTPEGDEEQLKIAVATQGPISIAIDAGHRSFQLYKKGVYYDEECSSEELDHGVLLVGYGTDPEHG-DYWIVKNSWGAGWGEKGYIRIARNRNNHCGVATKASYPLV 337
BLAST of Cathepsin L2 vs. Ensembl Celegans
Match: cpl-1 (CathePsin L family [Source:UniProtKB/TrEMBL;Acc:H9G333]) HSP 1 Score: 242.662 bits (618), Expect = 1.422e-79 Identity = 112/198 (56.57%), Postives = 150/198 (75.76%), Query Frame = 3 Query: 468 CGSCWSFSTTGSLEGQHYRKTQNLISFSEQQLVDCSGSFGNNGCDGGLMDSAFQYIQQ-YGIEAESTYPYTAQDGNCVYDKSKVVGSCTGFSDIPHGNEQALASAVATVGPISVAIDASNYSFQLYKSGIYNEPQCSSSQLDHGVLAIGYGT--ENGKNFWLVKNSWGIGWGIQGYIKMSKDQGNQCGISTMASYPLV 1052 CGSCW+FS TG+LEGQH RK L+S SEQ LVDCS +GN+GC+GGLMD AF+YI+ +G++ E +YPY +D C ++K V G+ D P G+E+ L AVAT GPIS+AIDA + SFQLYK G+Y + +CSS +LDHGVL +GYGT E+G ++W+VKNSWG GWG +GYI++++++ N CG++T ASYPLV Sbjct: 2 CGSCWAFSATGALEGQHARKLGQLVSLSEQNLVDCSTKYGNHGCNGGLMDQAFEYIRDNHGVDTEESYPYKGRDMKCHFNKKTVGADDKGYVDTPEGDEEQLKIAVATQGPISIAIDAGHRSFQLYKKGVYYDEECSSEELDHGVLLVGYGTDPEHG-DYWIVKNSWGAGWGEKGYIRIARNRNNHCGVATKASYPLV 198
BLAST of Cathepsin L2 vs. Ensembl Celegans
Match: cpl-1 (CathePsin L family [Source:UniProtKB/TrEMBL;Acc:H9G333]) HSP 1 Score: 242.662 bits (618), Expect = 1.422e-79 Identity = 112/198 (56.57%), Postives = 150/198 (75.76%), Query Frame = 3 Query: 468 CGSCWSFSTTGSLEGQHYRKTQNLISFSEQQLVDCSGSFGNNGCDGGLMDSAFQYIQQ-YGIEAESTYPYTAQDGNCVYDKSKVVGSCTGFSDIPHGNEQALASAVATVGPISVAIDASNYSFQLYKSGIYNEPQCSSSQLDHGVLAIGYGT--ENGKNFWLVKNSWGIGWGIQGYIKMSKDQGNQCGISTMASYPLV 1052 CGSCW+FS TG+LEGQH RK L+S SEQ LVDCS +GN+GC+GGLMD AF+YI+ +G++ E +YPY +D C ++K V G+ D P G+E+ L AVAT GPIS+AIDA + SFQLYK G+Y + +CSS +LDHGVL +GYGT E+G ++W+VKNSWG GWG +GYI++++++ N CG++T ASYPLV Sbjct: 2 CGSCWAFSATGALEGQHARKLGQLVSLSEQNLVDCSTKYGNHGCNGGLMDQAFEYIRDNHGVDTEESYPYKGRDMKCHFNKKTVGADDKGYVDTPEGDEEQLKIAVATQGPISIAIDAGHRSFQLYKKGVYYDEECSSEELDHGVLLVGYGTDPEHG-DYWIVKNSWGAGWGEKGYIRIARNRNNHCGVATKASYPLV 198
BLAST of Cathepsin L2 vs. Ensembl Celegans
Match: tag-196 (pep chromosome:WBcel235:V:8594914:8597500:1 gene:WBGene00007055.1 transcript:F41E6.6.2 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:tag-196) HSP 1 Score: 191.815 bits (486), Expect = 1.579e-56 Identity = 115/304 (37.83%), Postives = 172/304 (56.58%), Query Frame = 3 Query: 174 KKYVSLNEISRRL-IWEQNLKYIQQHNLEHDLGKHTYTLGLNHFADMTNEEFRANYLG------VSP-KRMNFTSHFIAPENVGALPSSVDWRTKGFVTPVKNQQQCGSCWSFSTTGSLEGQHYRKTQNLISFSEQQLVDCSGSFGNNGCDGGLMDSAF-QYIQQYGIEAESTYPYTAQDGNCVYDKSKVVGSCTGFSDIPHGNEQALASAVATVGPISVAIDASNYSFQLYKSGIYNEPQ--CSSSQLDHGVLAIGYGTENGKNFWLVKNSWGIGWGIQGYIKMSKDQGNQCGISTMASYPLV 1052 KKY + E+ +R ++++N K I++ +++ G Y G F+DMT EF+ L V P ++ NF H + N LP S DWR KG VT VKNQ CGSCW+FSTTG++EG + L+S SEQ+LVDC + GC+GGL +A+ + I+ G+E E YPY + C + + G ++PH +E + + T GPIS+ ++A+ + Q Y+ G+ + + C L+HGVL +GYG + K +W+VKNSWG WG GY K+ + + N CG+ MA+ LV Sbjct: 183 KKYTNKREVLKRFRVFKKNAKVIRELQ-KNEQGTAVY--GFTKFSDMTTMEFKKIMLPYQWEQPVYPMEQANFEKHDVTI-NEEDLPESFDWREKGAVTQVKNQGNCGSCWAFSTTGNVEGAWFIAKNKLVSLSEQELVDCDSM--DQGCNGGLPSNAYKEIIRMGGLEPEDAYPYDGRGETCHLVRKDIAVYINGSVELPH-DEVEMQKWLVTKGPISIGLNAN--TLQFYRHGVVHPFKIFCEPFMLNHGVLIVGYGKDGRKPYWIVKNSWGPNWGEAGYFKLYRGK-NVCGVQEMATSALV 476
BLAST of Cathepsin L2 vs. Ensembl Celegans
Match: tag-196 (pep chromosome:WBcel235:V:8594914:8597469:1 gene:WBGene00007055.1 transcript:F41E6.6.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:tag-196) HSP 1 Score: 191.815 bits (486), Expect = 1.579e-56 Identity = 115/304 (37.83%), Postives = 172/304 (56.58%), Query Frame = 3 Query: 174 KKYVSLNEISRRL-IWEQNLKYIQQHNLEHDLGKHTYTLGLNHFADMTNEEFRANYLG------VSP-KRMNFTSHFIAPENVGALPSSVDWRTKGFVTPVKNQQQCGSCWSFSTTGSLEGQHYRKTQNLISFSEQQLVDCSGSFGNNGCDGGLMDSAF-QYIQQYGIEAESTYPYTAQDGNCVYDKSKVVGSCTGFSDIPHGNEQALASAVATVGPISVAIDASNYSFQLYKSGIYNEPQ--CSSSQLDHGVLAIGYGTENGKNFWLVKNSWGIGWGIQGYIKMSKDQGNQCGISTMASYPLV 1052 KKY + E+ +R ++++N K I++ +++ G Y G F+DMT EF+ L V P ++ NF H + N LP S DWR KG VT VKNQ CGSCW+FSTTG++EG + L+S SEQ+LVDC + GC+GGL +A+ + I+ G+E E YPY + C + + G ++PH +E + + T GPIS+ ++A+ + Q Y+ G+ + + C L+HGVL +GYG + K +W+VKNSWG WG GY K+ + + N CG+ MA+ LV Sbjct: 183 KKYTNKREVLKRFRVFKKNAKVIRELQ-KNEQGTAVY--GFTKFSDMTTMEFKKIMLPYQWEQPVYPMEQANFEKHDVTI-NEEDLPESFDWREKGAVTQVKNQGNCGSCWAFSTTGNVEGAWFIAKNKLVSLSEQELVDCDSM--DQGCNGGLPSNAYKEIIRMGGLEPEDAYPYDGRGETCHLVRKDIAVYINGSVELPH-DEVEMQKWLVTKGPISIGLNAN--TLQFYRHGVVHPFKIFCEPFMLNHGVLIVGYGKDGRKPYWIVKNSWGPNWGEAGYFKLYRGK-NVCGVQEMATSALV 476
BLAST of Cathepsin L2 vs. Ensembl Fly
Match: Cp1 (gene:FBgn0013770 transcript:FBtr0087592) HSP 1 Score: 327.405 bits (838), Expect = 1.019e-110 Identity = 164/321 (51.09%), Postives = 219/321 (68.22%), Query Frame = 3 Query: 141 DEWEAYKTQFGKKYVSLNEISRRL-IWEQNLKYIQQHNLEHDLGKHTYTLGLNHFADMTNEEFRANYLGVSPKRMNFTSH--------------FIAPENVGALPSSVDWRTKGFVTPVKNQQQCGSCWSFSTTGSLEGQHYRKTQNLISFSEQQLVDCSGSFGNNGCDGGLMDSAFQYIQQY-GIEAESTYPYTAQDGNCVYDKSKVVGSCTGFSDIPHGNEQALASAVATVGPISVAIDASNYSFQLYKSGIYNEPQCSSSQLDHGVLAIGYGT-ENGKNFWLVKNSWGIGWGIQGYIKMSKDQGNQCGISTMASYPLV 1052 +EW +K + K Y E RL I+ +N I +HN GK ++ L +N +AD+ + EFR G N+T H FI+P +V LP SVDWRTKG VT VK+Q CGSCW+FS+TG+LEGQH+RK+ L+S SEQ LVDCS +GNNGC+GGLMD+AF+YI+ GI+ E +YPY A D +C ++K V + GF+DIP G+E+ +A AVATVGP+SVAIDAS+ SFQ Y G+YNEPQC + LDHGVL +G+GT E+G+++WLVKNSWG WG +G+IKM +++ NQCGI++ +SYPLV Sbjct: 27 EEWHTFKLEHRKNYQDETEERFRLKIFNENKHKIAKHNQRFAEGKVSFKLAVNKYADLLHHEFRQLMNG-----FNYTLHKQLRAADESFKGVTFISPAHV-TLPKSVDWRTKGAVTAVKDQGHCGSCWAFSSTGALEGQHFRKSGVLVSLSEQNLVDCSTKYGNNGCNGGLMDNAFRYIKDNGGIDTEKSYPYEAIDDSCHFNKGTVGATDRGFTDIPQGDEKKMAEAVATVGPVSVAIDASHESFQFYSEGVYNEPQCDAQNLDHGVLVVGFGTDESGEDYWLVKNSWGTTWGDKGFIKMLRNKENQCGIASASSYPLV 341
BLAST of Cathepsin L2 vs. Ensembl Fly
Match: Cp1 (gene:FBgn0013770 transcript:FBtr0087593) HSP 1 Score: 328.176 bits (840), Expect = 1.481e-110 Identity = 164/321 (51.09%), Postives = 219/321 (68.22%), Query Frame = 3 Query: 141 DEWEAYKTQFGKKYVSLNEISRRL-IWEQNLKYIQQHNLEHDLGKHTYTLGLNHFADMTNEEFRANYLGVSPKRMNFTSH--------------FIAPENVGALPSSVDWRTKGFVTPVKNQQQCGSCWSFSTTGSLEGQHYRKTQNLISFSEQQLVDCSGSFGNNGCDGGLMDSAFQYIQQY-GIEAESTYPYTAQDGNCVYDKSKVVGSCTGFSDIPHGNEQALASAVATVGPISVAIDASNYSFQLYKSGIYNEPQCSSSQLDHGVLAIGYGT-ENGKNFWLVKNSWGIGWGIQGYIKMSKDQGNQCGISTMASYPLV 1052 +EW +K + K Y E RL I+ +N I +HN GK ++ L +N +AD+ + EFR G N+T H FI+P +V LP SVDWRTKG VT VK+Q CGSCW+FS+TG+LEGQH+RK+ L+S SEQ LVDCS +GNNGC+GGLMD+AF+YI+ GI+ E +YPY A D +C ++K V + GF+DIP G+E+ +A AVATVGP+SVAIDAS+ SFQ Y G+YNEPQC + LDHGVL +G+GT E+G+++WLVKNSWG WG +G+IKM +++ NQCGI++ +SYPLV Sbjct: 57 EEWHTFKLEHRKNYQDETEERFRLKIFNENKHKIAKHNQRFAEGKVSFKLAVNKYADLLHHEFRQLMNG-----FNYTLHKQLRAADESFKGVTFISPAHV-TLPKSVDWRTKGAVTAVKDQGHCGSCWAFSSTGALEGQHFRKSGVLVSLSEQNLVDCSTKYGNNGCNGGLMDNAFRYIKDNGGIDTEKSYPYEAIDDSCHFNKGTVGATDRGFTDIPQGDEKKMAEAVATVGPVSVAIDASHESFQFYSEGVYNEPQCDAQNLDHGVLVVGFGTDESGEDYWLVKNSWGTTWGDKGFIKMLRNKENQCGIASASSYPLV 371
BLAST of Cathepsin L2 vs. Ensembl Fly
Match: Cp1 (gene:FBgn0013770 transcript:FBtr0339955) HSP 1 Score: 318.161 bits (814), Expect = 4.107e-107 Identity = 158/302 (52.32%), Postives = 210/302 (69.54%), Query Frame = 3 Query: 195 EISRRLIWEQNLKYIQQHNLEHDLGKHTYTLGLNHFADMTNEEFRANYLGVSPKRMNFTSH--------------FIAPENVGALPSSVDWRTKGFVTPVKNQQQCGSCWSFSTTGSLEGQHYRKTQNLISFSEQQLVDCSGSFGNNGCDGGLMDSAFQYIQQY-GIEAESTYPYTAQDGNCVYDKSKVVGSCTGFSDIPHGNEQALASAVATVGPISVAIDASNYSFQLYKSGIYNEPQCSSSQLDHGVLAIGYGT-ENGKNFWLVKNSWGIGWGIQGYIKMSKDQGNQCGISTMASYPLV 1052 E R I+ +N I +HN GK ++ L +N +AD+ + EFR G N+T H FI+P +V LP SVDWRTKG VT VK+Q CGSCW+FS+TG+LEGQH+RK+ L+S SEQ LVDCS +GNNGC+GGLMD+AF+YI+ GI+ E +YPY A D +C ++K V + GF+DIP G+E+ +A AVATVGP+SVAIDAS+ SFQ Y G+YNEPQC + LDHGVL +G+GT E+G+++WLVKNSWG WG +G+IKM +++ NQCGI++ +SYPLV Sbjct: 43 ERFRLKIFNENKHKIAKHNQRFAEGKVSFKLAVNKYADLLHHEFRQLMNG-----FNYTLHKQLRAADESFKGVTFISPAHV-TLPKSVDWRTKGAVTAVKDQGHCGSCWAFSSTGALEGQHFRKSGVLVSLSEQNLVDCSTKYGNNGCNGGLMDNAFRYIKDNGGIDTEKSYPYEAIDDSCHFNKGTVGATDRGFTDIPQGDEKKMAEAVATVGPVSVAIDASHESFQFYSEGVYNEPQCDAQNLDHGVLVVGFGTDESGEDYWLVKNSWGTTWGDKGFIKMLRNKENQCGIASASSYPLV 338
BLAST of Cathepsin L2 vs. Ensembl Fly
Match: Cp1 (gene:FBgn0013770 transcript:FBtr0304021) HSP 1 Score: 296.975 bits (759), Expect = 5.215e-100 Identity = 138/227 (60.79%), Postives = 180/227 (79.30%), Query Frame = 3 Query: 378 FIAPENVGALPSSVDWRTKGFVTPVKNQQQCGSCWSFSTTGSLEGQHYRKTQNLISFSEQQLVDCSGSFGNNGCDGGLMDSAFQYIQQY-GIEAESTYPYTAQDGNCVYDKSKVVGSCTGFSDIPHGNEQALASAVATVGPISVAIDASNYSFQLYKSGIYNEPQCSSSQLDHGVLAIGYGT-ENGKNFWLVKNSWGIGWGIQGYIKMSKDQGNQCGISTMASYPLV 1052 FI+P +V LP SVDWRTKG VT VK+Q CGSCW+FS+TG+LEGQH+RK+ L+S SEQ LVDCS +GNNGC+GGLMD+AF+YI+ GI+ E +YPY A D +C ++K V + GF+DIP G+E+ +A AVATVGP+SVAIDAS+ SFQ Y G+YNEPQC + LDHGVL +G+GT E+G+++WLVKNSWG WG +G+IKM +++ NQCGI++ +SYPLV Sbjct: 24 FISPAHV-TLPKSVDWRTKGAVTAVKDQGHCGSCWAFSSTGALEGQHFRKSGVLVSLSEQNLVDCSTKYGNNGCNGGLMDNAFRYIKDNGGIDTEKSYPYEAIDDSCHFNKGTVGATDRGFTDIPQGDEKKMAEAVATVGPVSVAIDASHESFQFYSEGVYNEPQCDAQNLDHGVLVVGFGTDESGEDYWLVKNSWGTTWGDKGFIKMLRNKENQCGIASASSYPLV 249
BLAST of Cathepsin L2 vs. Ensembl Fly
Match: CG5367 (gene:FBgn0032228 transcript:FBtr0080055) HSP 1 Score: 230.335 bits (586), Expect = 1.150e-72 Identity = 118/310 (38.06%), Postives = 194/310 (62.58%), Query Frame = 3 Query: 144 EWEAYKTQFGKKYV-SLNEISRRLIWEQNLKYIQQHNLEHDLGKHTYTLGLNHFADMTNEEFRANYLGVSPKRMNFTSHFIAPENVGA-----LPSSVDWRTKGFVTPVKNQQQCGSCWSFSTTGSLEGQHYRKTQNLISFSEQQLVDCSGSFGNNGCDGGLMDSAFQYIQQY-GIEAESTYPYTAQDGNCVYDKSKVVGSCTGFSDIPHGNEQALASAVATVGPISVAIDASNYSFQLYKSGIYNEPQCSSSQLDHGVLAIGYGTENGKNFWLVKNSWGIGWGIQGYIKMSKDQGNQCGISTMASYPLV 1052 E+E +K +KY+ + +E+ +E+N K I++HN + G+ ++ L N FADM+ + + +L + + ++ +A E VG+ +P S+DWR+KGF+TP NQ CGSC++FS S+ GQ +++T ++S S+QQ+VDCS S GN GC GG + + Y+Q GI + YPY A+ G C + V + T ++ +P +EQA+ +AV +GP++++I+AS +FQLY GIY++P CSS+ ++H ++ IG+ GK++W++KN WG WG GYI++ K N CGI+ A+Y +V Sbjct: 35 EFEKFKNNNNRKYLRTYDEMRSYKAFEENFKVIEEHNQNYKEGQTSFRLKPNIFADMSTDGYLKGFLRLLKSNIEDSADNMA-EIVGSPLMANVPESLDWRSKGFITPPYNQLSCGSCYAFSIAESIMGQVFKRTGKILSLSKQQIVDCSVSHGNQGCVGGSLRNTLSYLQSTGGIMRDQDYPYVARKGKCQFVPDLSVVNVTSWAILPVRDEQAIQAAVTHIGPVAISINASPKTFQLYSDGIYDDPLCSSASVNHAMVVIGF----GKDYWILKNWWGQNWGENGYIRIRKGV-NMCGIANYAAYAIV 338
BLAST of Cathepsin L2 vs. Ensembl Zebrafish
Match: ctsl.1 (cathepsin L.1 [Source:ZFIN;Acc:ZDB-GENE-040718-61]) HSP 1 Score: 375.555 bits (963), Expect = 1.344e-129 Identity = 181/310 (58.39%), Postives = 225/310 (72.58%), Query Frame = 3 Query: 144 EWEAYKTQFGKKYVSLNEIS-RRLIWEQNLKYIQQHNLEHDLGKHTYTLGLNHFADMTNEEFRANYLGVSPKRMNFT-----SHFIAPENVGALPSSVDWRTKGFVTPVKNQQQCGSCWSFSTTGSLEGQHYRKTQNLISFSEQQLVDCSGSFGNNGCDGGLMDSAFQYIQ-QYGIEAESTYPYTAQDGNCVYDKSKVVGSCTGFSDIPHGNEQALASAVATVGPISVAIDASNYSFQLYKSGIYNEPQCSSSQLDHGVLAIGYGTENGKNFWLVKNSWGIGWGIQGYIKMSKDQGNQCGISTMASYPLV 1052 E+ A+K +FGK Y S E S R+L W N K + HN+ D G +Y LG+ +FADM+NEE+R MN T S F +P +VDWR KG+VT +K+Q+QCGSCW+FS TGSLEGQ +RKT L+S SEQQLVDCSGS+GN GCDGGLMD AFQYI+ G++ E +YPY AQDG C ++ S V SCTG+ DI G+E AL AVAT+GPISVAIDA + SFQLY SG+YNEP CSSS+LDHGVLA+GYG+ NG ++W+VKNSWG+ WG+QGYI MS+++ NQCGI+T ASYPLV Sbjct: 25 EFHAWKLKFGKSYRSAEEESHRQLTWLTNRKLVLVHNMMADQGLKSYRLGMTYFADMSNEEYRQLVFRGCLGSMNNTKARGGSTFFRLRKAAVVPDTVDWRDKGYVTDIKDQKQCGSCWAFSATGSLEGQTFRKTGKLVSLSEQQLVDCSGSYGNYGCDGGLMDQAFQYIEANKGLDTEDSYPYEAQDGECRFNPSTVGASCTGYVDIASGDESALQEAVATIGPISVAIDAGHSSFQLYSSGVYNEPDCSSSELDHGVLAVGYGSSNGDDYWIVKNSWGLDWGVQGYILMSRNKSNQCGIATAASYPLV 334
BLAST of Cathepsin L2 vs. Ensembl Zebrafish
Match: ctsl.1 (cathepsin L.1 [Source:ZFIN;Acc:ZDB-GENE-040718-61]) HSP 1 Score: 375.555 bits (963), Expect = 1.344e-129 Identity = 181/310 (58.39%), Postives = 225/310 (72.58%), Query Frame = 3 Query: 144 EWEAYKTQFGKKYVSLNEIS-RRLIWEQNLKYIQQHNLEHDLGKHTYTLGLNHFADMTNEEFRANYLGVSPKRMNFT-----SHFIAPENVGALPSSVDWRTKGFVTPVKNQQQCGSCWSFSTTGSLEGQHYRKTQNLISFSEQQLVDCSGSFGNNGCDGGLMDSAFQYIQ-QYGIEAESTYPYTAQDGNCVYDKSKVVGSCTGFSDIPHGNEQALASAVATVGPISVAIDASNYSFQLYKSGIYNEPQCSSSQLDHGVLAIGYGTENGKNFWLVKNSWGIGWGIQGYIKMSKDQGNQCGISTMASYPLV 1052 E+ A+K +FGK Y S E S R+L W N K + HN+ D G +Y LG+ +FADM+NEE+R MN T S F +P +VDWR KG+VT +K+Q+QCGSCW+FS TGSLEGQ +RKT L+S SEQQLVDCSGS+GN GCDGGLMD AFQYI+ G++ E +YPY AQDG C ++ S V SCTG+ DI G+E AL AVAT+GPISVAIDA + SFQLY SG+YNEP CSSS+LDHGVLA+GYG+ NG ++W+VKNSWG+ WG+QGYI MS+++ NQCGI+T ASYPLV Sbjct: 25 EFHAWKLKFGKSYRSAEEESHRQLTWLTNRKLVLVHNMMADQGLKSYRLGMTYFADMSNEEYRQLVFRGCLGSMNNTKARGGSTFFRLRKAAVVPDTVDWRDKGYVTDIKDQKQCGSCWAFSATGSLEGQTFRKTGKLVSLSEQQLVDCSGSYGNYGCDGGLMDQAFQYIEANKGLDTEDSYPYEAQDGECRFNPSTVGASCTGYVDIASGDESALQEAVATIGPISVAIDAGHSSFQLYSSGVYNEPDCSSSELDHGVLAVGYGSSNGDDYWIVKNSWGLDWGVQGYILMSRNKSNQCGIATAASYPLV 334
BLAST of Cathepsin L2 vs. Ensembl Zebrafish
Match: ctsl.1 (cathepsin L.1 [Source:ZFIN;Acc:ZDB-GENE-040718-61]) HSP 1 Score: 375.555 bits (963), Expect = 1.344e-129 Identity = 181/310 (58.39%), Postives = 225/310 (72.58%), Query Frame = 3 Query: 144 EWEAYKTQFGKKYVSLNEIS-RRLIWEQNLKYIQQHNLEHDLGKHTYTLGLNHFADMTNEEFRANYLGVSPKRMNFT-----SHFIAPENVGALPSSVDWRTKGFVTPVKNQQQCGSCWSFSTTGSLEGQHYRKTQNLISFSEQQLVDCSGSFGNNGCDGGLMDSAFQYIQ-QYGIEAESTYPYTAQDGNCVYDKSKVVGSCTGFSDIPHGNEQALASAVATVGPISVAIDASNYSFQLYKSGIYNEPQCSSSQLDHGVLAIGYGTENGKNFWLVKNSWGIGWGIQGYIKMSKDQGNQCGISTMASYPLV 1052 E+ A+K +FGK Y S E S R+L W N K + HN+ D G +Y LG+ +FADM+NEE+R MN T S F +P +VDWR KG+VT +K+Q+QCGSCW+FS TGSLEGQ +RKT L+S SEQQLVDCSGS+GN GCDGGLMD AFQYI+ G++ E +YPY AQDG C ++ S V SCTG+ DI G+E AL AVAT+GPISVAIDA + SFQLY SG+YNEP CSSS+LDHGVLA+GYG+ NG ++W+VKNSWG+ WG+QGYI MS+++ NQCGI+T ASYPLV Sbjct: 25 EFHAWKLKFGKSYRSAEEESHRQLTWLTNRKLVLVHNMMADQGLKSYRLGMTYFADMSNEEYRQLVFRGCLGSMNNTKARGGSTFFRLRKAAVVPDTVDWRDKGYVTDIKDQKQCGSCWAFSATGSLEGQTFRKTGKLVSLSEQQLVDCSGSYGNYGCDGGLMDQAFQYIEANKGLDTEDSYPYEAQDGECRFNPSTVGASCTGYVDIASGDESALQEAVATIGPISVAIDAGHSSFQLYSSGVYNEPDCSSSELDHGVLAVGYGSSNGDDYWIVKNSWGLDWGVQGYILMSRNKSNQCGIATAASYPLV 334
BLAST of Cathepsin L2 vs. Ensembl Zebrafish
Match: ctsla (cathepsin La [Source:ZFIN;Acc:ZDB-GENE-030131-106]) HSP 1 Score: 363.229 bits (931), Expect = 1.154e-124 Identity = 176/318 (55.35%), Postives = 223/318 (70.13%), Query Frame = 3 Query: 120 TINSELNDEWEAYKTQFGKKYVSLNEISRRLIWEQNLKYIQQHNLEHDLGKHTYTLGLNHFADMTNEEFRANYLGVSPKR-MNFTSHFIAPENVGALPSSVDWRTKGFVTPVKNQQQCGSCWSFSTTGSLEGQHYRKTQNLISFSEQQLVDCSGSFGNNGCDGGLMDSAFQYIQ-QYGIEAESTYPYTAQDGN-CVYDKSKVVGSCTGFSDIPHGNEQALASAVATVGPISVAIDASNYSFQLYKSGIYNEPQCSSSQLDHGVLAIGYGTE----NGKNFWLVKNSWGIGWGIQGYIKMSKDQGNQCGISTMASYPLV 1052 T++ +LND W+ +K KKY + E RR+IWE+NLK I+ HNLEH +G HTY LG+NHF DMT+EEFR G K+ F N +P+ +DWR KG+VTPVK+Q +CGSCW+FSTTG+LEGQ +RKT L+S SEQ LVDCS GN GC+GGLMD AFQY++ Q G+++E +YPY D C +D + TGF DIP G E+AL A+A VGP+SVAIDA + SFQ Y+SGIY E +CSS +LDHGVLA+GYG E +GK +W+VKNSW WG +GYI M+KD+ N CGI+T ASYPLV Sbjct: 20 TLDQQLNDHWDQWKKWHSKKYHATEEGWRRIIWEKNLKKIEMHNLEHSMGIHTYRLGMNHFGDMTHEEFRQVMNGFKHKKDRRFRGSLFMEPNFIEVPNKLDWREKGYVTPVKDQGECGSCWAFSTTGALEGQMFRKTGKLVSLSEQNLVDCSRPEGNEGCNGGLMDQAFQYVKDQNGLDSEESYPYLGTDDQPCHFDPKNSAANDTGFVDIPSGKERALMKAIAAVGPVSVAIDAGHESFQFYQSGIYYEKECSSEELDHGVLAVGYGFEGEDVDGKKYWIVKNSWSENWGDKGYIYMAKDRHNHCGIATAASYPLV 337
BLAST of Cathepsin L2 vs. Ensembl Zebrafish
Match: ctsla (cathepsin La [Source:ZFIN;Acc:ZDB-GENE-030131-106]) HSP 1 Score: 363.229 bits (931), Expect = 1.154e-124 Identity = 176/318 (55.35%), Postives = 223/318 (70.13%), Query Frame = 3 Query: 120 TINSELNDEWEAYKTQFGKKYVSLNEISRRLIWEQNLKYIQQHNLEHDLGKHTYTLGLNHFADMTNEEFRANYLGVSPKR-MNFTSHFIAPENVGALPSSVDWRTKGFVTPVKNQQQCGSCWSFSTTGSLEGQHYRKTQNLISFSEQQLVDCSGSFGNNGCDGGLMDSAFQYIQ-QYGIEAESTYPYTAQDGN-CVYDKSKVVGSCTGFSDIPHGNEQALASAVATVGPISVAIDASNYSFQLYKSGIYNEPQCSSSQLDHGVLAIGYGTE----NGKNFWLVKNSWGIGWGIQGYIKMSKDQGNQCGISTMASYPLV 1052 T++ +LND W+ +K KKY + E RR+IWE+NLK I+ HNLEH +G HTY LG+NHF DMT+EEFR G K+ F N +P+ +DWR KG+VTPVK+Q +CGSCW+FSTTG+LEGQ +RKT L+S SEQ LVDCS GN GC+GGLMD AFQY++ Q G+++E +YPY D C +D + TGF DIP G E+AL A+A VGP+SVAIDA + SFQ Y+SGIY E +CSS +LDHGVLA+GYG E +GK +W+VKNSW WG +GYI M+KD+ N CGI+T ASYPLV Sbjct: 20 TLDQQLNDHWDQWKKWHSKKYHATEEGWRRIIWEKNLKKIEMHNLEHSMGIHTYRLGMNHFGDMTHEEFRQVMNGFKHKKDRRFRGSLFMEPNFIEVPNKLDWREKGYVTPVKDQGECGSCWAFSTTGALEGQMFRKTGKLVSLSEQNLVDCSRPEGNEGCNGGLMDQAFQYVKDQNGLDSEESYPYLGTDDQPCHFDPKNSAANDTGFVDIPSGKERALMKAIAAVGPVSVAIDAGHESFQFYQSGIYYEKECSSEELDHGVLAVGYGFEGEDVDGKKYWIVKNSWSENWGDKGYIYMAKDRHNHCGIATAASYPLV 337
BLAST of Cathepsin L2 vs. Ensembl Xenopus
Match: fcrl2 (Fc receptor-like 2 [Source:Xenbase;Acc:XB-GENE-5904272]) HSP 1 Score: 358.607 bits (919), Expect = 1.141e-122 Identity = 177/317 (55.84%), Postives = 226/317 (71.29%), Query Frame = 3 Query: 120 TINSELNDEWEAYKTQFGKKYVSLNEISRRLIWEQNLKYIQQHNLEHDLGKHTYTLGLNHFADMTNEEFRANYLGVSPKRMNFTSHFIAPENVGALPSSVDWRTKGFVTPVKNQQQCGSCWSFSTTGSLEGQHYRKTQNLISFSEQQLVDCSGSFGNNGCDGGLMDSAFQYIQQY-GIEAESTYPYTAQDG-NCVYDKSKVVGSCTGFSDIPHGNEQALASAVATVGPISVAIDASNYSFQLYKSGIYNEPQCSSSQLDHGVLAIGYG----TENGKNFWLVKNSWGIGWGIQGYIKMSKDQGNQCGISTMASYPLV 1052 T + L++ W +K K Y E RR++WE+NL+ I+ HNLEH LGKH+++LG+N F DMTNEEFR G ++ S F+AP N + P SVDWR KG+VTPVK+Q QCGSCW+FSTTG+LEGQHYR T +IS SEQ LVDCS + GN GC+GGLMD AFQY++ GI++E +YPYTA+D C YD + + TGF D+ G+E+ L +AVA+VGP+SVA+DA + SFQ YKSGIY EP+CSS LDHGVL +GYG E+GK +W+VKNSW WG GYI ++KD+ N CGI+T ASYPLV Sbjct: 20 TTDPALDNHWNLWKNWHKKSYAPKEEGWRRVLWEKNLRMIEFHNLEHSLGKHSHSLGMNQFGDMTNEEFRQLMNGYKNQKKIRGSTFLAPNNFES-PKSVDWRKKGYVTPVKDQGQCGSCWAFSTTGALEGQHYRNTGKMISLSEQNLVDCSRAQGNQGCNGGLMDQAFQYVKDNGGIDSEDSYPYTAKDDQECHYDPNYNSANDTGFVDVTSGSEKDLMNAVASVGPVSVAVDAGHQSFQFYKSGIYYEPECSSEDLDHGVLVVGYGFEGEDEDGKKYWIVKNSWSEKWGNDGYIYIAKDRHNHCGIATAASYPLV 335
BLAST of Cathepsin L2 vs. Ensembl Xenopus
Match: fcrl2 (Fc receptor-like 2 [Source:Xenbase;Acc:XB-GENE-5904272]) HSP 1 Score: 358.221 bits (918), Expect = 1.721e-122 Identity = 177/317 (55.84%), Postives = 226/317 (71.29%), Query Frame = 3 Query: 120 TINSELNDEWEAYKTQFGKKYVSLNEISRRLIWEQNLKYIQQHNLEHDLGKHTYTLGLNHFADMTNEEFRANYLGVSPKRMNFTSHFIAPENVGALPSSVDWRTKGFVTPVKNQQQCGSCWSFSTTGSLEGQHYRKTQNLISFSEQQLVDCSGSFGNNGCDGGLMDSAFQYIQQY-GIEAESTYPYTAQDG-NCVYDKSKVVGSCTGFSDIPHGNEQALASAVATVGPISVAIDASNYSFQLYKSGIYNEPQCSSSQLDHGVLAIGYG----TENGKNFWLVKNSWGIGWGIQGYIKMSKDQGNQCGISTMASYPLV 1052 T + L++ W +K K Y E RR++WE+NL+ I+ HNLEH LGKH+++LG+N F DMTNEEFR G ++ S F+AP N + P SVDWR KG+VTPVK+Q QCGSCW+FSTTG+LEGQHYR T +IS SEQ LVDCS + GN GC+GGLMD AFQY++ GI++E +YPYTA+D C YD + + TGF D+ G+E+ L +AVA+VGP+SVA+DA + SFQ YKSGIY EP+CSS LDHGVL +GYG E+GK +W+VKNSW WG GYI ++KD+ N CGI+T ASYPLV Sbjct: 27 TTDPALDNHWNLWKNWHKKSYAPKEEGWRRVLWEKNLRMIEFHNLEHSLGKHSHSLGMNQFGDMTNEEFRQLMNGYKNQKKIRGSTFLAPNNFES-PKSVDWRKKGYVTPVKDQGQCGSCWAFSTTGALEGQHYRNTGKMISLSEQNLVDCSRAQGNQGCNGGLMDQAFQYVKDNGGIDSEDSYPYTAKDDQECHYDPNYNSANDTGFVDVTSGSEKDLMNAVASVGPVSVAVDAGHQSFQFYKSGIYYEPECSSEDLDHGVLVVGYGFEGEDEDGKKYWIVKNSWSEKWGNDGYIYIAKDRHNHCGIATAASYPLV 342
BLAST of Cathepsin L2 vs. Ensembl Xenopus
Match: lrfn4 (leucine rich repeat and fibronectin type III domain containing 4 [Source:Xenbase;Acc:XB-GENE-6465078]) HSP 1 Score: 317.39 bits (812), Expect = 1.854e-106 Identity = 146/288 (50.69%), Postives = 201/288 (69.79%), Query Frame = 3 Query: 195 EISRRLIWEQNLKYIQQHNLEHDLGKHTYTLGLNHFADMTNEEFRANYLGVSPKRMNFTSHFIAPENV--GALPSSVDWRTKGFVTPVKNQQQCGSCWSFSTTGSLEGQHYRKTQNLISFSEQQLVDCSGSFGNNGCDGGLMDSAFQYIQQYGIEAESTYPYTAQDGNCVYDKSKVVGSCTGFSDIPHGNEQALASAVATVGPISVAIDASNYSFQLYKSGIYNEPQCSSSQLDHGVLAIGYGTENGKNFWLVKNSWGIGWGIQGYIKMSKDQGNQCGISTMASYPLV 1052 E +RR IWE+ LK+I HNLE+ LG HTY +G+NH DMT EE A G + R + + P+ + P+S+DWRT+G VT VKNQ CGSC++F T G+LE Q +K L+SFS Q+LVDCS + GNNGC GG + ++F+Y+++YGI ES+YPYTA++G C DK VG F +P G E L + TVGP+SVAID S F++YKSG+Y +P C ++++DH VL +GYGT+NGK++WLVKNSWG+G+G +GYIKM++++GN C I++ A YP V Sbjct: 49 ERARRTIWEETLKFITVHNLEYSLGLHTYEVGMNHLGDMTGEEVAATMTGYTGSRDSLANMTEVPKEILEAQTPASIDWRTQGCVTSVKNQGSCGSCYAFGTVGALECQWKKKMGTLVSFSPQELVDCSYTEGNNGCKGGYLQASFRYMKKYGIMEESSYPYTAKEGRCKKDKPSNVGVVKTFYVVPAGKELLLMKVLGTVGPVSVAIDCSREGFRMYKSGVYYDPYC-TTKVDHAVLVVGYGTDNGKDYWLVKNSWGVGYGDKGYIKMARNRGNNCAIASHAVYPTV 335
BLAST of Cathepsin L2 vs. Ensembl Xenopus
Match: lrfn4 (leucine rich repeat and fibronectin type III domain containing 4 [Source:Xenbase;Acc:XB-GENE-6465078]) HSP 1 Score: 315.464 bits (807), Expect = 1.634e-105 Identity = 146/288 (50.69%), Postives = 201/288 (69.79%), Query Frame = 3 Query: 195 EISRRLIWEQNLKYIQQHNLEHDLGKHTYTLGLNHFADMTNEEFRANYLGVSPKRMNFTSHFIAPENV--GALPSSVDWRTKGFVTPVKNQQQCGSCWSFSTTGSLEGQHYRKTQNLISFSEQQLVDCSGSFGNNGCDGGLMDSAFQYIQQYGIEAESTYPYTAQDGNCVYDKSKVVGSCTGFSDIPHGNEQALASAVATVGPISVAIDASNYSFQLYKSGIYNEPQCSSSQLDHGVLAIGYGTENGKNFWLVKNSWGIGWGIQGYIKMSKDQGNQCGISTMASYPLV 1052 E +RR IWE+ LK+I HNLE+ LG HTY +G+NH DMT EE A G + R + + P+ + P+S+DWRT+G VT VKNQ CGSC++F T G+LE Q +K L+SFS Q+LVDCS + GNNGC GG + ++F+Y+++YGI ES+YPYTA++G C DK VG F +P G E L + TVGP+SVAID S F++YKSG+Y +P C ++++DH VL +GYGT+NGK++WLVKNSWG+G+G +GYIKM++++GN C I++ A YP V Sbjct: 63 ERARRTIWEETLKFITVHNLEYSLGLHTYEVGMNHLGDMTGEEVAATMTGYTGSRDSLANMTEVPKEILEAQTPASIDWRTQGCVTSVKNQGSCGSCYAFGTVGALECQWKKKMGTLVSFSPQELVDCSYTEGNNGCKGGYLQASFRYMKKYGIMEESSYPYTAKEGRCKKDKPSNVGVVKTFYVVPAGKELLLMKVLGTVGPVSVAIDCSREGFRMYKSGVYYDPYC-TTKVDHAVLVVGYGTDNGKDYWLVKNSWGVGYGDKGYIKMARNRGNNCAIASHAVYPTV 349
BLAST of Cathepsin L2 vs. Ensembl Xenopus
Match: lrfn4 (leucine rich repeat and fibronectin type III domain containing 4 [Source:Xenbase;Acc:XB-GENE-6465078]) HSP 1 Score: 309.301 bits (791), Expect = 1.605e-103 Identity = 145/288 (50.35%), Postives = 199/288 (69.10%), Query Frame = 3 Query: 195 EISRRLIWEQNLKYIQQHNLEHDLGKHTYTLGLNHFADMTNEEFRANYLGVSPKRMNFTSHFIAPENV--GALPSSVDWRTKGFVTPVKNQQQCGSCWSFSTTGSLEGQHYRKTQNLISFSEQQLVDCSGSFGNNGCDGGLMDSAFQYIQQYGIEAESTYPYTAQDGNCVYDKSKVVGSCTGFSDIPHGNEQALASAVATVGPISVAIDASNYSFQLYKSGIYNEPQCSSSQLDHGVLAIGYGTENGKNFWLVKNSWGIGWGIQGYIKMSKDQGNQCGISTMASYPLV 1052 E +RR IWE+ LK+I HNLE+ LG HTY +G+NH DMT EE A G + R + + P+ + P+S+DWRT+G VT VKNQ CGSC++F T G+LE Q +K L+SFS Q+LVDCS + GNNGC GG + ++F+Y+++YGI ES+YPYT +G C DK VG F +P G E L + TVGP+SVAID S F++YKSG+Y +P C ++++DH VL +GYGT+NGK++WLVKNSWG+G+G +GYIKM++++GN C I++ A YP V Sbjct: 43 ERARRTIWEETLKFITVHNLEYSLGLHTYEVGMNHLGDMTGEEVAATMTGYTGSRDSLANMTEVPKEILEAQTPASIDWRTQGCVTSVKNQGSCGSCYAFGTVGALECQWKKKMGTLVSFSPQELVDCSYTEGNNGCKGGYLQASFRYMKKYGIMEESSYPYT--EGRCKKDKPSNVGVVKTFYVVPAGKELLLMKVLGTVGPVSVAIDCSREGFRMYKSGVYYDPYC-TTKVDHAVLVVGYGTDNGKDYWLVKNSWGVGYGDKGYIKMARNRGNNCAIASHAVYPTV 327
BLAST of Cathepsin L2 vs. Ensembl Mouse
Match: Ctsl (cathepsin L [Source:MGI Symbol;Acc:MGI:88564]) HSP 1 Score: 330.872 bits (847), Expect = 6.328e-112 Identity = 168/308 (54.55%), Postives = 212/308 (68.83%), Query Frame = 3 Query: 144 EWEAYKTQFGKKYVSLNEISRRLIWEQNLKYIQQHNLEHDLGKHTYTLGLNHFADMTNEEFRANYLGVSPKRMNFTSHFIAPENVGALPSSVDWRTKGFVTPVKNQQQCGSCWSFSTTGSLEGQHYRKTQNLISFSEQQLVDCSGSFGNNGCDGGLMDSAFQYIQQY-GIEAESTYPYTAQDGNCVYDKSKVVGSCTGFSDIPHGNEQALASAVATVGPISVAIDASNYSFQLYKSGIYNEPQCSSSQLDHGVLAIGYGTE----NGKNFWLVKNSWGIGWGIQGYIKMSKDQGNQCGISTMASYPLV 1052 EW +K+ + Y + E RR IWE+N++ IQ HN E+ G+H +++ +N F DMTNEEFR G ++ F P + +P SVDWR KG VTPVKNQ QCGSCW+FS +G LEGQ + KT LIS SEQ LVDCS + GN GC+GGLMD AFQYI++ G+++E +YPY A+DG+C Y V + TGF DIP E+AL AVATVGPISVA+DAS+ S Q Y SGIY EP CSS LDHGVL +GYG E N +WLVKNSWG WG++GYIK++KD+ N CG++T ASYP+V Sbjct: 28 EWHQWKSTHRRLYGTNEEEWRRAIWEKNMRMIQLHNGEYSNGQHGFSMEMNAFGDMTNEEFRQVVNGYRHQKHKKGRLFQEPLML-KIPKSVDWREKGCVTPVKNQGQCGSCWAFSASGCLEGQMFLKTGKLISLSEQNLVDCSHAQGNQGCNGGLMDFAFQYIKENGGLDSEESYPYEAKDGSCKYRAEFAVANDTGFVDIPQ-QEKALMKAVATVGPISVAMDASHPSLQFYSSGIYYEPNCSSKNLDHGVLLVGYGYEGTDSNKNKYWLVKNSWGSEWGMEGYIKIAKDRDNHCGLATAASYPVV 333
BLAST of Cathepsin L2 vs. Ensembl Mouse
Match: Ctsl (cathepsin L [Source:MGI Symbol;Acc:MGI:88564]) HSP 1 Score: 330.872 bits (847), Expect = 6.328e-112 Identity = 168/308 (54.55%), Postives = 212/308 (68.83%), Query Frame = 3 Query: 144 EWEAYKTQFGKKYVSLNEISRRLIWEQNLKYIQQHNLEHDLGKHTYTLGLNHFADMTNEEFRANYLGVSPKRMNFTSHFIAPENVGALPSSVDWRTKGFVTPVKNQQQCGSCWSFSTTGSLEGQHYRKTQNLISFSEQQLVDCSGSFGNNGCDGGLMDSAFQYIQQY-GIEAESTYPYTAQDGNCVYDKSKVVGSCTGFSDIPHGNEQALASAVATVGPISVAIDASNYSFQLYKSGIYNEPQCSSSQLDHGVLAIGYGTE----NGKNFWLVKNSWGIGWGIQGYIKMSKDQGNQCGISTMASYPLV 1052 EW +K+ + Y + E RR IWE+N++ IQ HN E+ G+H +++ +N F DMTNEEFR G ++ F P + +P SVDWR KG VTPVKNQ QCGSCW+FS +G LEGQ + KT LIS SEQ LVDCS + GN GC+GGLMD AFQYI++ G+++E +YPY A+DG+C Y V + TGF DIP E+AL AVATVGPISVA+DAS+ S Q Y SGIY EP CSS LDHGVL +GYG E N +WLVKNSWG WG++GYIK++KD+ N CG++T ASYP+V Sbjct: 28 EWHQWKSTHRRLYGTNEEEWRRAIWEKNMRMIQLHNGEYSNGQHGFSMEMNAFGDMTNEEFRQVVNGYRHQKHKKGRLFQEPLML-KIPKSVDWREKGCVTPVKNQGQCGSCWAFSASGCLEGQMFLKTGKLISLSEQNLVDCSHAQGNQGCNGGLMDFAFQYIKENGGLDSEESYPYEAKDGSCKYRAEFAVANDTGFVDIPQ-QEKALMKAVATVGPISVAMDASHPSLQFYSSGIYYEPNCSSKNLDHGVLLVGYGYEGTDSNKNKYWLVKNSWGSEWGMEGYIKIAKDRDNHCGLATAASYPVV 333
BLAST of Cathepsin L2 vs. Ensembl Mouse
Match: Ctsk (cathepsin K [Source:MGI Symbol;Acc:MGI:107823]) HSP 1 Score: 321.242 bits (822), Expect = 3.246e-108 Identity = 157/316 (49.68%), Postives = 208/316 (65.82%), Query Frame = 3 Query: 117 FTINSE--LNDEWEAYKTQFGKKYVS-LNEISRRLIWEQNLKYIQQHNLEHDLGKHTYTLGLNHFADMTNEEF--RANYLGVSPKRMNFTSHFIAPENVGALPSSVDWRTKGFVTPVKNQQQCGSCWSFSTTGSLEGQHYRKTQNLISFSEQQLVDCSGSFGNNGCDGGLMDSAFQYIQQYG-IEAESTYPYTAQDGNCVYDKSKVVGSCTGFSDIPHGNEQALASAVATVGPISVAIDASNYSFQLYKSGIYNEPQCSSSQLDHGVLAIGYGTENGKNFWLVKNSWGIGWGIQGYIKMSKDQGNQCGISTMASYP 1046 F ++ E L+ +WE +K K+Y S ++EISRRLIWE+NLK I HNLE LG HTY L +NH DMT+EE + L + P R PE G +P S+D+R KG+VTPVKNQ QCGSCW+FS+ G+LEGQ +KT L++ S Q LVDC N GC GG M +AFQY+QQ G I++E YPY QD +C+Y+ + C G+ +IP GNE+AL AVA VGPISV+IDAS SFQ Y G+Y + C ++H VL +GYGT+ G W++KNSWG WG +GY +++++ N CGI+ MAS+P Sbjct: 14 FALSPEEMLDTQWELWKKTHQKQYNSKVDEISRRLIWEKNLKQISAHNLEASLGVHTYELAMNHLGDMTSEEVVQKMTGLRIPPSRSYSNDTLYTPEWEGRVPDSIDYRKKGYVTPVKNQGQCGSCWAFSSAGALEGQLKKKTGKLLALSPQNLVDCVTE--NYGCGGGYMTTAFQYVQQNGGIDSEDAYPYVGQDESCMYNATAKAAKCRGYREIPVGNEKALKRAVARVGPISVSIDASLASFQFYSRGVYYDENCDRDNVNHAVLVVGYGTQKGSKHWIIKNSWGESWGNKGYALLARNKNNACGITNMASFP 327
BLAST of Cathepsin L2 vs. Ensembl Mouse
Match: Ctsll3 (cathepsin L-like 3 [Source:MGI Symbol;Acc:MGI:1917452]) HSP 1 Score: 317.39 bits (812), Expect = 9.901e-107 Identity = 156/311 (50.16%), Postives = 201/311 (64.63%), Query Frame = 3 Query: 126 NSELNDEWEAYKTQFGKKYVSLNEISRRLIWEQNLKYIQQHNLEHDLGKHTYTLGLNHFADMTNEEFRANYLGVSPKRMNFTSHFIAPENVGALPSSVDWRTKGFVTPVKNQQQCGSCWSFSTTGSLEGQHYRKTQNLISFSEQQLVDCSGSFGNNGCDGGLMDSAFQYIQQY-GIEAESTYPYTAQDGNCVYDKSKVVGSCTGFSDIPHGNEQALASAVATVGPISVAIDASNYSFQLYKSGIYNEPQCSSSQLDHGVLAIGYGTE-NGKNFWLVKNSWGIGWGIQGYIKMSKDQGNQCGISTMASYPLV 1052 N L+ WE +KT+ K Y +E +R +WE N K I HN ++ GKH ++L +N F D+TN EFR G ++ +G +P SVDWR G+VTPVK+Q CGSCW+FS GSLEGQ +RKT L+ S Q LVDCS S GN GCDGGL D AFQY++ G++ +YPY A +G C Y+ + TGF ++ +E AL AVATVGPISV ID + SFQ YK G+Y EP CSS+ LDH VL +GYG E +G+ +WLVKNSWG WG+ GYIKM+KD+ N CGI++ ASYP+V Sbjct: 22 NPSLDAVWEEWKTKHKKTYNMNDEGQKRAVWENNKKMIDLHNEDYLKGKHGFSLEMNAFGDLTNTEFRELMTGFQGQKTKMMMKVFQEPLLGDVPKSVDWRDHGYVTPVKDQGSCGSCWAFSAVGSLEGQMFRKTGKLVPLSVQNLVDCSWSQGNQGCDGGLPDLAFQYVKDNGGLDTSVSYPYEALNGTCRYNPKNSAATVTGFVNV-QSSEDALMKAVATVGPISVGIDTKHKSFQFYKEGMYYEPDCSSTVLDHAVLVVGYGEESDGRKYWLVKNSWGRDWGMNGYIKMAKDRNNNCGIASDASYPVV 331
BLAST of Cathepsin L2 vs. Ensembl Mouse
Match: BC051665 (cDNA sequence BC051665 [Source:MGI Symbol;Acc:MGI:2682300]) HSP 1 Score: 311.612 bits (797), Expect = 2.066e-104 Identity = 154/311 (49.52%), Postives = 203/311 (65.27%), Query Frame = 3 Query: 126 NSELNDEWEAYKTQFGKKYVSLNEISRRLIWEQNLKYIQQHNLEHDLGKHTYTLGLNHFADMTNEEFRANYLGVSPKRMNFTSHFIAPENVGALPSSVDWRTKGFVTPVKNQQQCGSCWSFSTTGSLEGQHYRKTQNLISFSEQQLVDCSGSFGNNGCDGGLMDSAFQYIQQ-YGIEAESTYPYTAQDGNCVYDKSKVVGSCTGFSDIPHGNEQALASAVATVGPISVAIDASNYSFQLYKSGIYNEPQCSSSQLDHGVLAIGYGTE-NGKNFWLVKNSWGIGWGIQGYIKMSKDQGNQCGISTMASYPLV 1052 + L+ WE +KT+ K Y E +R +WE N+K I HN ++ GKH + L +N F D+TN EFR G + F P +G +P SVDWR G+VTPVK+Q CGSCW+FS GSLEGQ +RKT L+ SEQ L+DCS S+GN GC+GGLM+ AFQY+++ G++ +Y Y A DG C YD + TGF +P +E AL +AVA+VGP+SV ID ++SF+ Y+ G Y EP CSS+ LDH VL +GYG E +G+ +WLVKNSWG WG+ GYIKM+KD+ N CGI+T A YP V Sbjct: 22 DPSLDAVWEEWKTKHRKTYNMNEEAQKRAVWENNMKMIGLHNEDYLKGKHGFNLEMNAFGDLTNTEFRELMTGFQSMGHKEMTIFQEPL-LGDVPKSVDWRDHGYVTPVKDQGHCGSCWAFSAVGSLEGQIFRKTGKLVPLSEQNLMDCSWSYGNVGCNGGLMELAFQYVKENRGLDTRESYAYEAWDGPCRYDPKYSAVNITGFVKVPL-SEDALMNAVASVGPVSVGIDTHHHSFRFYRGGTYYEPDCSSTNLDHAVLVVGYGEESDGRKYWLVKNSWGEDWGMDGYIKMAKDRDNNCGIATYAIYPTV 330
BLAST of Cathepsin L2 vs. UniProt/SwissProt
Match: sp|P25782|CYSP2_HOMAM (Digestive cysteine proteinase 2 OS=Homarus americanus OX=6706 GN=LCP2 PE=2 SV=1) HSP 1 Score: 348.977 bits (894), Expect = 2.338e-118 Identity = 167/304 (54.93%), Postives = 218/304 (71.71%), Query Frame = 3 Query: 147 WEAYKTQFGKKYVSLNEIS-RRLIWEQNLKYIQQHNLEHDLGKHTYTLGLNHFADMTNEEFRANYLGVSPKRMNFTSHFIAPENVGALPSSVDWRTKGFVTPVKNQQQCGSCWSFSTTGSLEGQHYRKTQNLISFSEQQLVDCSGSFGNNGCDGGLMDSAFQYIQ-QYGIEAESTYPYTAQDGNCVYDKSKVVGSCTGFSDIPHGNEQALASAVATVGPISVAIDASNYSFQLYKSGIYNEPQCSSSQLDHGVLAIGYGTENGKNFWLVKNSWGIGWGIQGYIKMSKDQGNQCGISTMASYPLV 1052 WE +K ++G++YV E S RR+I+EQN KYI++ N +++ G+ T+ L +N F DMT EEF A G P+R S F + G + VDWRTKG VTPVK+Q QCGSCW+FSTTGSLEGQH+ KT +LIS +EQQLVDCS +G GC+GG M+ AF YI+ GI+ E+ YPY A+DG+C +D + V +C+G ++I G+E L AV +GPISV IDA++ SFQ Y SG+Y EP CS S LDH VLA+GYG+E G++FWLVKNSW WG GYIKMS+++ N CGI+T+ASYPLV Sbjct: 20 WEHFKGKYGRQYVDAEEDSYRRVIFEQNQKYIEEFNKKYENGEVTFNLAMNKFGDMTLEEFNAVMKGNIPRRSAPVSVFYPKKETGPQATEVDWRTKGAVTPVKDQGQCGSCWAFSTTGSLEGQHFLKTGSLISLAEQQLVDCSRPYGPQGCNGGWMNDAFDYIKANNGIDTEAAYPYEARDGSCRFDSNSVAATCSGHTNIASGSETGLQQAVRDIGPISVTIDAAHSSFQFYSSGVYYEPSCSPSYLDHAVLAVGYGSEGGQDFWLVKNSWATSWGDAGYIKMSRNRNNNCGIATVASYPLV 323
BLAST of Cathepsin L2 vs. UniProt/SwissProt
Match: sp|Q24940|CATLL_FASHE (Cathepsin L-like proteinase OS=Fasciola hepatica OX=6192 GN=Cat-1 PE=1 SV=1) HSP 1 Score: 337.035 bits (863), Expect = 1.043e-113 Identity = 155/306 (50.65%), Postives = 217/306 (70.92%), Query Frame = 3 Query: 138 NDEWEAYKTQFGKKYVSLNEISRRLIWEQNLKYIQQHNLEHDLGKHTYTLGLNHFADMTNEEFRANYLGVSPKRMNFTSHFIAPE-NVGALPSSVDWRTKGFVTPVKNQQQCGSCWSFSTTGSLEGQHYRKTQNLISFSEQQLVDCSGSFGNNGCDGGLMDSAFQYIQQYGIEAESTYPYTAQDGNCVYDKSKVVGSCTGFSDIPHGNEQALASAVATVGPISVAIDASNYSFQLYKSGIYNEPQCSSSQLDHGVLAIGYGTENGKNFWLVKNSWGIGWGIQGYIKMSKDQGNQCGISTMASYPLV 1052 +D W +K + K+Y ++ RR IWE+N+K+IQ+HNL HDLG TYTLGLN F DMT EEF+A YL + + SH + E N A+P +DWR G+VT VK+Q CGSCW+FSTTG++EGQ+ + + ISFSEQQLVDCSG +GNNGC GGLM++A+QY++Q+G+E ES+YPYTA +G C Y+K V TG+ + G+E L + V P +VA+D + F +Y+SGIY CS +++H VLA+GYGT+ G ++W+VKNSWG WG +GYI+M++++GN CGI+++AS P+V Sbjct: 18 DDLWHQWKRMYNKEYNGADDQHRRNIWEKNVKHIQEHNLRHDLGLVTYTLGLNQFTDMTFEEFKAKYLTEMSRASDILSHGVPYEANNRAVPDKIDWRESGYVTEVKDQGNCGSCWAFSTTGTMEGQYMKNERTSISFSEQQLVDCSGPWGNNGCSGGLMENAYQYLKQFGLETESSYPYTAVEGQCRYNKQLGVAKVTGYYTVHSGSEVELKNLVGARRPAAVAVDVES-DFMMYRSGIYQSQTCSPLRVNHAVLAVGYGTQGGTDYWIVKNSWGTYWGERGYIRMARNRGNMCGIASLASLPMV 322
BLAST of Cathepsin L2 vs. UniProt/SwissProt
Match: sp|Q9GKL8|CATL1_CHLAE (Cathepsin L1 OS=Chlorocebus aethiops OX=9534 GN=CTSL PE=1 SV=1) HSP 1 Score: 334.339 bits (856), Expect = 1.512e-112 Identity = 169/317 (53.31%), Postives = 210/317 (66.25%), Query Frame = 3 Query: 117 FTINSELNDEWEAYKTQFGKKYVSLNEISRRLIWEQNLKYIQQHNLEHDLGKHTYTLGLNHFADMTNEEFRANYLGVSPKRMNFTSHFIAPENVGALPSSVDWRTKGFVTPVKNQQQCGSCWSFSTTGSLEGQHYRKTQNLISFSEQQLVDCSGSFGNNGCDGGLMDSAFQYIQQY-GIEAESTYPYTAQDGNCVYDKSKVVGSCTGFSDIPHGNEQALASAVATVGPISVAIDASNYSFQLYKSGIYNEPQCSSSQLDHGVLAIGYGTE----NGKNFWLVKNSWGIGWGIQGYIKMSKDQGNQCGISTMASYPLV 1052 T N L +W +K + Y E RR +WE+N+K I+ HN E+ GKH++T+ +N F DMT+EEFR G ++ F P A P SVDWR KG+VTPVKNQ QCGSCW+FS TG+LEGQ +RKT L+S SEQ LVDCSG GN GC+GGLMD AFQY+ G+++E +YPY A + +C Y+ V + TGF DIP E+AL AVATVGPISVAIDA + SF YK GIY EP CSS +DHGVL +GYG E + +WLVKNSWG WG+ GYIKM+KD+ N CGI++ ASYP V Sbjct: 19 LTFNHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIELHNQEYSQGKHSFTMAMNTFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEA-PRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVADNGGLDSEESYPYEATEESCKYNPEYSVANDTGFVDIPK-QEKALMKAVATVGPISVAIDAGHESFMFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNSKYWLVKNSWGEEWGMGGYIKMAKDRRNHCGIASAASYPTV 333
BLAST of Cathepsin L2 vs. UniProt/SwissProt
Match: sp|P07711|CATL1_HUMAN (Cathepsin L1 OS=Homo sapiens OX=9606 GN=CTSL PE=1 SV=2) HSP 1 Score: 334.339 bits (856), Expect = 1.943e-112 Identity = 169/317 (53.31%), Postives = 211/317 (66.56%), Query Frame = 3 Query: 117 FTINSELNDEWEAYKTQFGKKYVSLNEISRRLIWEQNLKYIQQHNLEHDLGKHTYTLGLNHFADMTNEEFRANYLGVSPKRMNFTSHFIAPENVGALPSSVDWRTKGFVTPVKNQQQCGSCWSFSTTGSLEGQHYRKTQNLISFSEQQLVDCSGSFGNNGCDGGLMDSAFQYIQQY-GIEAESTYPYTAQDGNCVYDKSKVVGSCTGFSDIPHGNEQALASAVATVGPISVAIDASNYSFQLYKSGIYNEPQCSSSQLDHGVLAIGYGTE----NGKNFWLVKNSWGIGWGIQGYIKMSKDQGNQCGISTMASYPLV 1052 T + L +W +K + Y E RR +WE+N+K I+ HN E+ GKH++T+ +N F DMT+EEFR G ++ F P A P SVDWR KG+VTPVKNQ QCGSCW+FS TG+LEGQ +RKT LIS SEQ LVDCSG GN GC+GGLMD AFQY+Q G+++E +YPY A + +C Y+ V + TGF DIP E+AL AVATVGPISVAIDA + SF YK GIY EP CSS +DHGVL +GYG E + +WLVKNSWG WG+ GY+KM+KD+ N CGI++ ASYP V Sbjct: 19 LTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIELHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEA-PRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPK-QEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV 333
BLAST of Cathepsin L2 vs. UniProt/SwissProt
Match: sp|P07154|CATL1_RAT (Cathepsin L1 OS=Rattus norvegicus OX=10116 GN=Ctsl PE=1 SV=2) HSP 1 Score: 331.643 bits (849), Expect = 2.021e-111 Identity = 168/311 (54.02%), Postives = 211/311 (67.85%), Query Frame = 3 Query: 135 LNDEWEAYKTQFGKKYVSLNEISRRLIWEQNLKYIQQHNLEHDLGKHTYTLGLNHFADMTNEEFRANYLGVSPKRMNFTSHFIAPENVGALPSSVDWRTKGFVTPVKNQQQCGSCWSFSTTGSLEGQHYRKTQNLISFSEQQLVDCSGSFGNNGCDGGLMDSAFQYIQQY-GIEAESTYPYTAQDGNCVYDKSKVVGSCTGFSDIPHGNEQALASAVATVGPISVAIDASNYSFQLYKSGIYNEPQCSSSQLDHGVLAIGYGTE----NGKNFWLVKNSWGIGWGIQGYIKMSKDQGNQCGISTMASYPLV 1052 N +W +K+ + Y + E RR +WE+N++ IQ HN E+ GKH +T+ +N F DMTNEEFR G ++ F P + +P +VDWR KG VTPVKNQ QCGSCW+FS +G LEGQ + KT LIS SEQ LVDCS GN GC+GGLMD AFQYI++ G+++E +YPY A+DG+C Y V + TGF DIP E+AL AVATVGPISVA+DAS+ S Q Y SGIY EP CSS LDHGVL +GYG E N +WLVKNSWG WG+ GYIK++KD+ N CG++T ASYP+V Sbjct: 25 FNAQWHQWKSTHRRLYGTNEEEWRRAVWEKNMRMIQLHNGEYSNGKHGFTMEMNAFGDMTNEEFRQIVNGYRHQKHKKGRLFQEPLML-QIPKTVDWREKGCVTPVKNQGQCGSCWAFSASGCLEGQMFLKTGKLISLSEQNLVDCSHDQGNQGCNGGLMDFAFQYIKENGGLDSEESYPYEAKDGSCKYRAEYAVANDTGFVDIPQ-QEKALMKAVATVGPISVAMDASHPSLQFYSSGIYYEPNCSSKDLDHGVLVVGYGYEGTDSNKDKYWLVKNSWGKEWGMDGYIKIAKDRNNHCGLATAASYPIV 333
BLAST of Cathepsin L2 vs. TrEMBL
Match: A0A2U8U447 (Cathepsin L2 OS=Dugesia japonica OX=6161 PE=2 SV=1) HSP 1 Score: 505.368 bits (1300), Expect = 1.901e-177 Identity = 239/333 (71.77%), Postives = 279/333 (83.78%), Query Frame = 3 Query: 57 MQIIIXXXXXXXXXXXXPQQFTINSELNDEWEAYKTQFGKKYVSLNEISRRLIWEQNLKYIQQHNLEHDLGKHTYTLGLNHFADMTNEEFRANYLGVSPKRMNFTS-HFIAPENVGALPSSVDWRTKGFVTPVKNQQQCGSCWSFSTTGSLEGQHYRKTQNLISFSEQQLVDCSGSFGNNGCDGGLMDSAFQYIQQYGIEAESTYPYTAQDGNCVYDKSKVVGSCTGFSDIPHGNEQALASAVATVGPISVAIDASNYSFQLYKSGIYNEPQCSSSQLDHGVLAIGYGTENGKNFWLVKNSWGIGWGIQGYIKMSKDQGNQCGISTMASYPLV 1052 M+II+L S+FL + A P +FTINSELNDEWE YK +F KKY +LNEISRR+IWE NLK+IQQHN+E+DLGKHTY LGLN FADMT+EEF+A YLG+ P NFTS FI PEN+G LP+ +DWRTKG+VTPVKNQ QCGSCW+FSTTGSLEGQH+RK+ L+SFSEQQLVDCS SF N GC+GGLMD+AF YIQ++GIE E +YPY A DG C YDK+K+VG+CTGF DI GNE L +AVAT GPISVAIDASN SFQ Y+ GIYNEP CSS LDHGVLAIGYG+EN +N+W+VKNSW I WG+ GYI+MSKD+ NQCGI+TMASYPLV Sbjct: 1 MKIILLTSIFLVTIQAVPHKFTINSELNDEWEVYKMKFSKKYETLNEISRRIIWENNLKFIQQHNVEYDLGKHTYYLGLNEFADMTHEEFKAKYLGLKPINRNFTSSRFIIPENIGDLPTRIDWRTKGYVTPVKNQGQCGSCWAFSTTGSLEGQHFRKSGKLVSFSEQQLVDCSRSFDNLGCNGGLMDNAFSYIQKFGIENEISYPYVANDGVCAYDKTKIVGTCTGFVDIKTGNETDLMAAVATQGPISVAIDASNDSFQFYRGGIYNEPHCSSKDLDHGVLAIGYGSENNENYWIVKNSWDISWGMSGYIRMSKDKMNQCGIATMASYPLV 333
BLAST of Cathepsin L2 vs. TrEMBL
Match: A0A267H1I6 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig013052g1 PE=3 SV=1) HSP 1 Score: 416.772 bits (1070), Expect = 1.564e-142 Identity = 197/314 (62.74%), Postives = 243/314 (77.39%), Query Frame = 3 Query: 114 QFTINSELNDEWEAYKTQFGKKYVSLNEISRRLIWEQNLKYIQQHNLEHDLGKHTYTLGLNHFADMTNEEFRANYLGVSPKRMNFTSHFIAPENVGALPSSVDWRTKGFVTPVKNQQQCGSCWSFSTTGSLEGQHYRKTQNLISFSEQQLVDCSGSFGNNGCDGGLMDSAFQYIQ-QYGIEAESTYPYTAQDGNCVYDKSKVVGSCTGFSDIPHGNEQALASAVATVGPISVAIDASNYSFQLYKSGIYNEPQCSSSQLDHGVLAIGYGTENGKNFWLVKNSWGIGWGIQGYIKMSKDQGNQCGISTMASYPLV 1052 QFT+ ELN+EWEAYK+ GK Y + E+ RRLIWEQNL++IQ+HNLE+D G H+YTLG+N F D+T EF+A YL P S F+ NVG+LP VDWRTKG+VT VK+Q+QCGSCW+FSTTGSLEGQH++KT NL+S SEQ LVDCSG FGN GC+GGLMD+ F+YI+ GI+ E+ YPY A+D C + S V + +GF DIP NE AL AVAT+GPISVAIDA + SFQLYKSG+Y+E CS +QLDHGVLA+GYGTE GK +WLVKNSWG WG++GYI MS+++ NQCGI++ ASYPLV Sbjct: 20 QFTL--ELNEEWEAYKSTHGKVYEADEELMRRLIWEQNLQHIQKHNLEYDRGVHSYTLGMNQFGDLTFTEFKAKYLSPMPAAEPEGSVFLPASNVGSLPDEVDWRTKGYVTGVKDQKQCGSCWAFSTTGSLEGQHFKKTGNLVSLSEQNLVDCSGKFGNMGCNGGLMDNGFKYIKANKGIDTEACYPYKARDEKCSFKSSCVGATVSGFVDIPAKNESALQQAVATIGPISVAIDAGHSSFQLYKSGVYSERLCSETQLDHGVLAVGYGTEGGKAYWLVKNSWGTSWGMKGYIMMSRNKKNQCGIASAASYPLV 331
BLAST of Cathepsin L2 vs. TrEMBL
Match: A0A1I8GVB7 (Uncharacterized protein OS=Macrostomum lignano OX=282301 PE=3 SV=1) HSP 1 Score: 416.772 bits (1070), Expect = 1.745e-142 Identity = 197/314 (62.74%), Postives = 243/314 (77.39%), Query Frame = 3 Query: 114 QFTINSELNDEWEAYKTQFGKKYVSLNEISRRLIWEQNLKYIQQHNLEHDLGKHTYTLGLNHFADMTNEEFRANYLGVSPKRMNFTSHFIAPENVGALPSSVDWRTKGFVTPVKNQQQCGSCWSFSTTGSLEGQHYRKTQNLISFSEQQLVDCSGSFGNNGCDGGLMDSAFQYIQ-QYGIEAESTYPYTAQDGNCVYDKSKVVGSCTGFSDIPHGNEQALASAVATVGPISVAIDASNYSFQLYKSGIYNEPQCSSSQLDHGVLAIGYGTENGKNFWLVKNSWGIGWGIQGYIKMSKDQGNQCGISTMASYPLV 1052 QFT+ ELN+EWEAYK+ GK Y + E+ RRLIWEQNL++IQ+HNLE+D G H+YTLG+N F D+T EF+A YL P S F+ NVG+LP VDWRTKG+VT VK+Q+QCGSCW+FSTTGSLEGQH++KT NL+S SEQ LVDCSG FGN GC+GGLMD+ F+YI+ GI+ E+ YPY A+D C + S V + +GF DIP NE AL AVAT+GPISVAIDA + SFQLYKSG+Y+E CS +QLDHGVLA+GYGTE GK +WLVKNSWG WG++GYI MS+++ NQCGI++ ASYPLV Sbjct: 20 QFTL--ELNEEWEAYKSTHGKVYEADEELMRRLIWEQNLQHIQKHNLEYDRGVHSYTLGMNQFGDLTFTEFKAKYLSPMPAAEPEGSVFLPASNVGSLPDEVDWRTKGYVTGVKDQKQCGSCWAFSTTGSLEGQHFKKTGNLVSLSEQNLVDCSGKFGNMGCNGGLMDNGFKYIKANKGIDTEACYPYKARDEKCSFKSSCVGATVSGFVDIPAKNESALQHAVATIGPISVAIDAGHSSFQLYKSGVYSERLCSETQLDHGVLAVGYGTEGGKAYWLVKNSWGTSWGMKGYIMMSRNKKNQCGIASAASYPLV 331
BLAST of Cathepsin L2 vs. TrEMBL
Match: A0A0L8HPF9 (Uncharacterized protein OS=Octopus bimaculoides OX=37653 GN=OCBIM_22009826mg PE=3 SV=1) HSP 1 Score: 394.43 bits (1012), Expect = 1.027e-133 Identity = 183/311 (58.84%), Postives = 237/311 (76.21%), Query Frame = 3 Query: 135 LNDEWEAYKTQFGKKY-VSLNEISRRLIWEQNLKYIQQHNLEHDLGKHTYTLGLNHFADMTNEEFRANYLGVSPKRMNFTSH----FIAPENVGALPSSVDWRTKGFVTPVKNQQQCGSCWSFSTTGSLEGQHYRKTQNLISFSEQQLVDCSGSFGNNGCDGGLMDSAFQYIQQYGIEAESTYPYTAQDGNCVYDKSKVVGSCTGFSDIPHGNEQALASAVATVGPISVAIDASNYSFQLYKSGIYNEPQCSSSQLDHGVLAIGYGTENGKNFWLVKNSWGIGWGIQGYIKMSKDQGNQCGISTMASYPLV 1052 L+ W+ Y F KKY + NE RR+IWE+NL+Y+ QHNLE D+G HTY LGLN +AD+ N EF + P+ N T++ A +N+ LP +VDWRTKG+VT VKNQ QCGSCW+FSTTGSLEGQ ++KT L+S SEQ LVDCSGSFGNNGC+GGLMD+AF+YI+++GI++E++YPY +D C Y KS VV + TG+ D+ +E +L SAVA VGPISVAIDA + SFQLYK G+Y E +CS++ LDHGVLA+GYGT+NG+++WLVKNSWG WG++GYIKM+++Q N CGI+T ASYP V Sbjct: 26 LDQSWQTYMKLFNKKYNTAENEFVRRVIWEKNLQYVNQHNLEADMGLHTYWLGLNEYADLENREFVQRMNNLIPR--NLTTYKPKLIFANDNIKDLPDTVDWRTKGYVTEVKNQAQCGSCWAFSTTGSLEGQIFKKTGKLVSLSEQNLVDCSGSFGNNGCEGGLMDNAFKYIKKFGIDSEASYPYEGRDAKCRYKKSDVVATDTGYVDVKSMSEDSLQSAVAKVGPISVAIDAGHLSFQLYKHGVYKESRCSATALDHGVLAVGYGTDNGQDYWLVKNSWGGSWGVKGYIKMARNQNNMCGIATQASYPTV 334
BLAST of Cathepsin L2 vs. TrEMBL
Match: A0A4Y2J2Y6 (Cathepsin L OS=Araneus ventricosus OX=182803 GN=Cp1_0 PE=3 SV=1) HSP 1 Score: 393.275 bits (1009), Expect = 3.546e-133 Identity = 187/317 (58.99%), Postives = 236/317 (74.45%), Query Frame = 3 Query: 111 QQFTINSELNDEWEAYKTQFGKKYVSLNEISRRLIWEQNLKYIQQHNLEHDLGKHTYTLGLNHFADMTNEEFRANYLGVS--PKRMNFTSHFIAPENVGALPSSVDWRTKGFVTPVKNQQQCGSCWSFSTTGSLEGQHYRKTQNLISFSEQQLVDCSGSFGNNGCDGGLMDSAFQYIQQ-YGIEAESTYPYTAQDGNCVYDKSKVVGSCTGFSDIPHGNEQALASAVATVGPISVAIDASNYSFQLYKSGIYNEPQCSSSQLDHGVLAIGYGTENGKNFWLVKNSWGIGWGIQGYIKMSKDQGNQCGISTMASYPLV 1052 + + ELN+ WE +K FGK Y E+SRR+IWEQ + + +HNL +DLG H+Y G+N ++DM +EEF + G P + + + ++ NV +P VDWRTKG VTP+KNQQQCGSCW+FSTTGSLEGQH +KT L+S SEQ LVDCSG GN GC+GGLMD AF+YI+ GI+ E +YPYTA+DG C + KS V + TG+ DIP G+E+AL AVATVGP+SVAIDAS SFQ Y+ GIY+EPQCSS LDHGVLA+GYGTE+G ++WLVKNSWG WGI+GYIKMS+++ NQCGI+T ASYPLV Sbjct: 16 RHIQFDPELNEHWENFKKVFGKVYDGTEEVSRRMIWEQRVSDVVRHNLRYDLGFHSYRKGINEYSDMEHEEFVRIFNGFRRHPGQKSNATTWVPAFNV-QIPDQVDWRTKGLVTPIKNQQQCGSCWAFSTTGSLEGQHKKKTGKLVSLSEQNLVDCSGPEGNQGCEGGLMDQAFEYIKDNKGIDTEDSYPYTAEDGTCHFKKSSVGATVTGYVDIPTGDEEALKQAVATVGPVSVAIDASQNSFQTYQDGIYDEPQCSSEFLDHGVLAVGYGTEDGSDYWLVKNSWGTTWGIKGYIKMSRNKNNQCGIATQASYPLV 331
BLAST of Cathepsin L2 vs. Ensembl Cavefish
Match: ctsl.1 (cathepsin L1-like [Source:NCBI gene;Acc:103023607]) HSP 1 Score: 364.385 bits (934), Expect = 3.095e-125 Identity = 177/309 (57.28%), Postives = 229/309 (74.11%), Query Frame = 3 Query: 144 EWEAYKTQFGKKYVSLNEIS-RRLIWEQNLKYIQQHNLEHDLGKHTYTLGLNHFADMTNEEFR---ANYLG-VSPKRMNFTSHFIAPENVGALPSSVDWRTKGFVTPVKNQQQCGSCWSFSTTGSLEGQHYRKTQNLISFSEQQLVDCSGSFGNNGCDGGLMDSAFQYIQ-QYGIEAESTYPYTAQDGNCVYDKSKVVGSCTGFSDIPHGNEQALASAVATVGPISVAIDASNYSFQLYKSGIYNEPQCSSSQLDHGVLAIGYGTENGKNFWLVKNSWGIGWGIQGYIKMSKDQGNQCGISTMASYPLV 1052 E+ A+K +FGK Y S+ E S R+L W N K + HN+ D G +Y LG+ FADM N+E+R A+ LG + + + + F+ LP +VDWR KG+VT +K+Q+ CGSCW+FS TGSLEGQ +RKT L+S SEQQLVDCSG +GN GC GGLMD AF+YI+ GI+ E +YPY A DG+C + V +CTGF DI G+E+AL AVAT+GPISVAIDA + SFQLY+SGIYNEP CSS++LDHGVLA+GYGT+NGK++WLVKNSWG+ WG +GYI+MS+++ NQCGI+TM+SYPLV Sbjct: 25 EFHAWKLKFGKIYHSVEEESQRKLTWLTNRKLVLVHNMLADQGIKSYRLGMTFFADMDNKEYRKLFASCLGSFNRTKAHSATTFLRQTLRDPLPDTVDWRPKGYVTDIKDQKDCGSCWAFSATGSLEGQTFRKTGKLVSLSEQQLVDCSGDYGNFGCGGGLMDQAFEYIKANKGIDTEDSYPYEAVDGDCRFKPDSVGATCTGFVDITSGDEKALQEAVATIGPISVAIDAGHSSFQLYESGIYNEPDCSSTELDHGVLAVGYGTDNGKDYWLVKNSWGLDWGNKGYIQMSRNEDNQCGIATMSSYPLV 333
BLAST of Cathepsin L2 vs. Ensembl Cavefish
Match: si:dkey-26g8.5 (cathepsin L1-like [Source:NCBI gene;Acc:103028700]) HSP 1 Score: 358.607 bits (919), Expect = 7.348e-123 Identity = 175/319 (54.86%), Postives = 227/319 (71.16%), Query Frame = 3 Query: 120 TINSELNDEWEAYKTQFGKKYVSLNEISRRLIWEQNLKYIQQHNLEHDLGKHTYTLGLNHFADMTNEEFRANYLGV--SPKRMNFTSHFIAPENVGALPSSVDWRTKGFVTPVKNQQQCGSCWSFSTTGSLEGQHYRKTQNLISFSEQQLVDCSGSFGNNGCDGGLMDSAFQYIQQY-GIEAESTYPYTAQDGN-CVYDKSKVVGSCTGFSDIPHGNEQALASAVATVGPISVAIDASNYSFQLYKSGIYNEPQCSSSQLDHGVLAIGYG----TENGKNFWLVKNSWGIGWGIQGYIKMSKDQGNQCGISTMASYPLV 1052 +++ +L+D W+ +K+ K Y E RRL+WE+NLK ++ HNLEH +GKHTY LG+N FADMTNEEFR G +P + + S F+ P + +P VDWR KG+VTPVK+Q +CGSCW+FS+TG+LEGQH+RKT L+S SEQ LVDCS GN GC+GG+M+ AFQY++ GI++E +YPYTA+D C YD + + TGF DIP G E AL AVA VGP+SVAIDA + SFQ Y+SGIY E CSS +LDHGVL +GYG E+GK +W+VKNSW WG GYI M+KD+ N CGI++ ASYPL+ Sbjct: 21 SLDRQLDDHWKLWKSWHSKSYHEKEEGWRRLVWEKNLKKVELHNLEHSMGKHTYRLGMNQFADMTNEEFRQAMNGYRSNPNKKSKGSLFLEPSFL-EVPKQVDWREKGYVTPVKDQARCGSCWAFSSTGALEGQHFRKTGKLVSLSEQNLVDCSRPEGNQGCNGGIMEQAFQYVKDNGGIDSEESYPYTAKDDQPCRYDPNFNSANDTGFVDIPSGEEHALMKAVAAVGPVSVAIDAGHESFQFYQSGIYYEKACSSEELDHGVLVVGYGFEGADEDGKKYWIVKNSWSEKWGQNGYIYMAKDRKNHCGIASAASYPLM 338
BLAST of Cathepsin L2 vs. Ensembl Cavefish
Match: ENSAMXT00000042132.1 (cathepsin L1-like [Source:NCBI gene;Acc:103023924]) HSP 1 Score: 339.732 bits (870), Expect = 1.207e-115 Identity = 163/308 (52.92%), Postives = 213/308 (69.16%), Query Frame = 3 Query: 144 EWEAYKTQFGKKYVSLNEISRRLIWEQNLKYIQQHNLEHDLGKHTYTLGLNHFADMTNEEFRANYLGV----SPKRMNFTSHFIAPENVGALPSSVDWRTKGFVTPVKNQQQCGSCWSFSTTGSLEGQHYRKTQNLISFSEQQLVDCSGSFGNNGCDGGLMDSAFQYIQQYG-IEAESTYPYTAQDGNCVYDKSKVVGSCTGFSDIPHGNEQALASAVATVGPISVAIDASNYSFQLYKSGIYNEPQCSSSQLDHGVLAIGYGTENGKNFWLVKNSWGIGWGIQGYIKMSKDQGNQCGISTMASYPLV 1052 E+ A+K + GK Y E R++ W N K + HN+ D G TY LG+ HFADM N+E+R G + + S F+ LP++VDWRT+G+VT VKNQ+ CGSCW+FS TG+LEGQ +RK L+ SEQQLVDCS +GN GC GG M+ AFQY++ G ++ E +YPY A +G C Y V +C+G+ DI G+EQAL AVATVGP+SVAID +YSFQLY+SG+Y+EP CS+S L H VLA+GYG++ G+++WLVKNSWG WG QGYIKMS+++ NQCGI+T ASYPLV Sbjct: 25 EFHAWKLKLGKVYNPAEESQRKITWLANRKLVLVHNMLADQGLKTYRLGMTHFADMDNQEYRQMLQGCLGSFNETKAPGASSFLRQAGGATLPNTVDWRTQGYVTEVKNQEMCGSCWAFSATGALEGQMFRKLGYLLPLSEQQLVDCSREYGNMGCSGGWMNQAFQYVKDNGGLDTEDSYPYEAMEGYCRYYPDAVGATCSGYVDISIGDEQALQEAVATVGPVSVAIDVGHYSFQLYQSGVYDEPDCSTSALGHAVLAVGYGSDYGQDYWLVKNSWGTYWGDQGYIKMSRNKNNQCGIATAASYPLV 332
BLAST of Cathepsin L2 vs. Ensembl Cavefish
Match: ENSAMXT00000048039.1 (cathepsin L1-like [Source:NCBI gene;Acc:103023924]) HSP 1 Score: 339.732 bits (870), Expect = 1.207e-115 Identity = 163/308 (52.92%), Postives = 213/308 (69.16%), Query Frame = 3 Query: 144 EWEAYKTQFGKKYVSLNEISRRLIWEQNLKYIQQHNLEHDLGKHTYTLGLNHFADMTNEEFRANYLGV----SPKRMNFTSHFIAPENVGALPSSVDWRTKGFVTPVKNQQQCGSCWSFSTTGSLEGQHYRKTQNLISFSEQQLVDCSGSFGNNGCDGGLMDSAFQYIQQYG-IEAESTYPYTAQDGNCVYDKSKVVGSCTGFSDIPHGNEQALASAVATVGPISVAIDASNYSFQLYKSGIYNEPQCSSSQLDHGVLAIGYGTENGKNFWLVKNSWGIGWGIQGYIKMSKDQGNQCGISTMASYPLV 1052 E+ A+K + GK Y E R++ W N K + HN+ D G TY LG+ HFADM N+E+R G + + S F+ LP++VDWRT+G+VT VKNQ+ CGSCW+FS TG+LEGQ +RK L+ SEQQLVDCS +GN GC GG M+ AFQY++ G ++ E +YPY A +G C Y V +C+G+ DI G+EQAL AVATVGP+SVAID +YSFQLY+SG+Y+EP CS+S L H VLA+GYG++ G+++WLVKNSWG WG QGYIKMS+++ NQCGI+T ASYPLV Sbjct: 25 EFHAWKLKLGKVYNPAEESQRKITWLANRKLVLVHNMLADQGLKTYRLGMTHFADMDNQEYRQMLQGCLGSFNETKAPGASSFLRQAGGATLPNTVDWRTQGYVTEVKNQEMCGSCWAFSATGALEGQMFRKLGYLLPLSEQQLVDCSREYGNMGCSGGWMNQAFQYVKDNGGLDTEDSYPYEAMEGYCRYYPDAVGATCSGYVDISIGDEQALQEAVATVGPVSVAIDVGHYSFQLYQSGVYDEPDCSTSALGHAVLAVGYGSDYGQDYWLVKNSWGTYWGDQGYIKMSRNKNNQCGIATAASYPLV 332
BLAST of Cathepsin L2 vs. Ensembl Cavefish
Match: ENSAMXT00000034892.1 (cathepsin L1-like [Source:NCBI gene;Acc:107196839]) HSP 1 Score: 334.724 bits (857), Expect = 1.240e-113 Identity = 166/311 (53.38%), Postives = 218/311 (70.10%), Query Frame = 3 Query: 144 EWEAYKTQFGKKYVSLNEIS-RRLIWEQNLKYIQQHNLEHDLGKHTYTLGLNHFADMTNEEFRANYLGVSPKRMN-----FTSHFIAPENVGALPSSVDWRTKGFVTPVKNQQQCGSCWSFSTTGSLEGQHYRKTQNLISFSEQQLVDCSGSFGNNGCDGGLMDSAFQYIQ-QYGIEAESTYPYTAQDGNCVYDKSKVVGSCTGFSDIPHGNEQALASAVATVGPISVAIDASNYSFQLYKSGIYNEPQCSSSQLDHGVLAIGYG-TENGKNFWLVKNSWGIGWGIQGYIKMSKDQGNQCGISTMASYPLV 1052 E+ ++K Q GK Y S E S R++IW N K + +HN+ D G +Y LG+N F DM N+EF+A + K N TS F++ E LP VDWR KG+VT VK+Q CGSCW+FS TG+LEGQ +RKT LIS SE+QLVDCS SFGN GC+GG +F+YI+ G+EA+ TYPY ++ C ++ +VV +C+GF +P G+E AL AVA +GPISVAID S ++FQLYKSG+Y+EP CSS++L+H V+ +GYG GK +WLVKNSWGIGWG GYIKMS+++ NQCGI+T A+YPLV Sbjct: 26 EFNSWKLQHGKSYDSEEEESQRKMIWLNNRKLVLEHNMLADQGLKSYRLGMNIFGDMENQEFQAMF-SHCVKSFNETDSLCTSTFLSEEEDTPLPRRVDWRKKGYVTDVKDQMSCGSCWAFSATGALEGQMFRKTGKLISLSEKQLVDCSQSFGNRGCNGGWPSKSFEYIKSNQGLEADFTYPYKPREETCRFNPQRVVATCSGFECLPQGDENALKKAVAKIGPISVAIDTSKHTFQLYKSGVYDEPGCSSTRLNHAVVLVGYGNAPRGKQYWLVKNSWGIGWGDNGYIKMSRNKMNQCGIATDATYPLV 335
BLAST of Cathepsin L2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006499.1 (pep scaffold:Pmarinus_7.0:GL477089:42202:47941:1 gene:ENSPMAG00000005817.1 transcript:ENSPMAT00000006499.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 359.377 bits (921), Expect = 6.375e-124 Identity = 178/315 (56.51%), Postives = 225/315 (71.43%), Query Frame = 3 Query: 135 LNDEWEAYKTQFGKKYVSLNEISRRLIWEQNLKYIQQHNLEHDLGKHTYTLGLNHFADMTNEEFRAN---YLGVSPKRMNFTSHFIAPENVGALPSSVDWRTKGFVTPVKNQQQCGSCWSFSTTGSLEGQHYRKTQNLISFSEQQLVDCSGSFGNNGCDGGLMDSAFQYIQQY-GIEAESTYPYTAQDGN-CVYDKSKVVGSCTGFSDIPHGNEQALASAVATVGPISVAIDASNYSFQLYKSGIYNEPQCSSSQLDHGVLAIGYGT----ENGKNFWLVKNSWGIGWGIQGYIKMSKDQGNQCGISTMASYPLV 1052 L++EW ++K K Y E RR+IWE+NL I+ HNLEH LGKHT+ +G+NHF DMTNEEFR Y GV P +++ S F+ P+N A P +VDWR KG VT VK+Q +CGSCW+FSTTG+LEGQH RK L+S SEQ LVDCS + GN GC GGLMD AFQY++ GI++E+ YPYT DG+ C YD + TGF D+ G+E+AL AVA+VGP+SVAIDAS+ SFQ Y+SG+Y EP CSS LDHGVL +GYG ENGK +W+VKNSW WG +GY+ M++++ N CGI+T ASYPLV Sbjct: 26 LDEEWGSWKGFHQKLYEPKQESWRRMIWEKNLNKIKIHNLEHSLGKHTWRMGMNHFGDMTNEEFRQKMNGYHGVQPHKVSKGSTFLVPQNYEA-PPTVDWRDKGLVTEVKDQGECGSCWAFSTTGALEGQHMRKVGQLVSLSEQNLVDCSRAEGNQGCGGGLMDQAFQYVKDNGGIDSEAAYPYTGTDGDKCHYDPKFNSANDTGFVDVTSGDEKALKIAVASVGPVSVAIDASHESFQFYQSGVYFEPDCSSQDLDHGVLVVGYGVKGTGENGKKYWIVKNSWSPKWGDEGYVLMARNKKNHCGIATAASYPLV 339
BLAST of Cathepsin L2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000011285.1 (pep scaffold:Pmarinus_7.0:GL499136:454:1347:-1 gene:ENSPMAG00000010258.1 transcript:ENSPMAT00000011285.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 344.739 bits (883), Expect = 1.089e-118 Identity = 171/299 (57.19%), Postives = 215/299 (71.91%), Query Frame = 3 Query: 174 KKYVSLNEISRRLIWEQNLKYIQQHNLEHDLGKHTYTLGLNHFADMTNEEFRANYLGV----SPKRMNFTSHFIAPENVGALPSSVDWRTKGFVTPVKNQQQCGSCWSFSTTGSLEGQHYRKTQNLISFSEQQLVDCSGSFGNNGCDGGLMDSAFQYIQQY-GIEAESTYPYTAQDGNCVYDKSKVVGSCTGFSDIPHGNEQALASAVATVGPISVAIDASNYSFQLYKSGIYNEPQCSSSQLDHGVLAIGYGTENG-KNFWLVKNSWGIGWGIQGYIKMSKDQGNQCGISTMASYPLV 1052 K Y E RR+IWE+NLK I HNLEH +GKHT+ +G+N F DMT EEF+ LG+ + + + F+AP A P SVDWR +G+VT VK+Q CGSCW+FSTTGSLEGQH RKT L+S SEQ LVDCS + GNNGC GGLMD AF YI++ GI++E++YPYTA+D NC Y+ TGF DIP GNE+AL +AVA+VGP+S+ IDAS SFQLY SGIY++ CS++ LDHGVL +GYG ++ + FW+VKNSWG WG GYI M++D+ N CGI+T ASYPLV Sbjct: 1 KTYDQNEEGWRRMIWEKNLKKIAVHNLEHSMGKHTWRMGMNRFGDMTKEEFQHTMLGLRGSNDTSKASRGATFMAPAFFKA-PESVDWRKQGYVTDVKDQGDCGSCWAFSTTGSLEGQHKRKTGVLVSLSEQNLVDCSSAEGNNGCKGGLMDLAFTYIKKNGGIDSEASYPYTAKDENCKYNPKNKAAEDTGFVDIPSGNEEALKNAVASVGPVSIGIDASLESFQLYSSGIYSDSDCSNN-LDHGVLVVGYGVDDDERKFWIVKNSWGTKWGDHGYILMARDKDNLCGIATAASYPLV 297
BLAST of Cathepsin L2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000010475.1 (pep scaffold:Pmarinus_7.0:GL482653:10321:33550:-1 gene:ENSPMAG00000009483.1 transcript:ENSPMAT00000010475.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 332.028 bits (850), Expect = 6.933e-114 Identity = 167/291 (57.39%), Postives = 208/291 (71.48%), Query Frame = 3 Query: 204 RRLIWEQNLKYIQQHNLEHDLGKHTYTLGLNHFADMTNEEFRANYLGVSPKRMNFTSH------FIAPENVGALPSSVDWRTKGFVTPVKNQQQCGSCWSFSTTGSLEGQHYRKTQNLISFSEQQLVDCSGSFGNNGCDGGLMDSAFQYIQQY-GIEAESTYPYTAQDGNCVYDKSKVVGSCTGFSDIPHGNEQALASAVATVGPISVAIDASNYSFQLYKSGIYNEPQCSSSQLDHGVLAIGYGT-ENGKNFWLVKNSWGIGWGIQGYIKMSKDQGNQCGISTMASYPLV 1052 RR+IWE+NLK I HNLEH +GKHT+ +G+N F+DMT EEF+ LG + N TS F+AP A P SVDWR +G+VT +KNQ CGSCWSFSTTGSLEGQH RKT L+S SEQ LVDCS + GN+GC+GGLM +AF YI++ GI++E +YPY Q C YD TG+ +IP G+E+AL +AVA+VGP+SVAIDAS SFQ Y SGIY + C S +DH VL +GYG E G+ FWLVKNSWG+ WG QGY++M++D N CGI+TM+SYPLV Sbjct: 7 RRIIWEKNLKRISVHNLEHSMGKHTWRMGMNQFSDMTGEEFQQVMLGF--RGWNGTSKAPRGATFMAPAFFEA-PESVDWRKQGYVTDIKNQGDCGSCWSFSTTGSLEGQHKRKTGVLVSLSEQNLVDCSSTEGNHGCNGGLMINAFNYIKKNGGIDSEESYPYKGQVETCKYDPKNKAAEVTGYVEIPEGDEEALMNAVASVGPVSVAIDASLASFQSYGSGIYKDAMC-SHHIDHAVLVVGYGVDEMGQKFWLVKNSWGVTWGEQGYVRMARDDNNLCGIATMSSYPLV 293
BLAST of Cathepsin L2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008535.1 (pep scaffold:Pmarinus_7.0:GL478103:36116:54424:1 gene:ENSPMAG00000007699.1 transcript:ENSPMAT00000008535.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 322.013 bits (824), Expect = 4.049e-109 Identity = 161/319 (50.47%), Postives = 220/319 (68.97%), Query Frame = 3 Query: 126 NSELNDEWEAYKTQFGKKYVSLNEISRRLIWEQNLKYIQQHNLEHDLGKHTYTLGLNHFADMTNEEFRAN---YLGVSPKRM--NFTSHFIAPENVGALPSSVDWRTKGFVTPVKNQQQCGSCWSFSTTGSLEGQHYRKTQNLISFSEQQLVDCSGSFGNNGCDGGLMDSAFQYI-QQYGIEAESTYPYTAQD-GNCVYDKSKVVGSCTGFSDIPHGNEQALASAVATVGPISVAIDASNYSFQLYKSGIYNEPQCSSSQLDHGVLAIGYGT----ENGKNFWLVKNSWGIGWGIQGYIKMSKDQGNQCGISTMASYPL 1049 + L+ WEA+ F K Y + I RRLIWE+N++++ +HNLEH LG H+YTLG+NH AD+T +EFR Y S +R + TS F+APEN +P S+DWR +G VTP+KNQ QCGSCW+FS+TG+LEGQ R++ L+ SEQ L+DCS G GC GG MD AFQY+ Q GI++ES YPYTA D +C YD S++V +GF DI G+E+ L +AVA+VGP+SVAIDA + SFQLY+SGIY EP+C+ ++LDH VL +G+G ENGK FW+VKN G+ G + Y++++ D+ CG+ + + L Sbjct: 29 DPALDGHWEAWTVYFKKAYTQTDGIKRRLIWEENMRFVDRHNLEHSLGLHSYTLGMNHLADLTVDEFRKTMNGYRRGSRERHEGHHTSTFLAPENY-EVPQSMDWRDQGLVTPIKNQGQCGSCWAFSSTGALEGQWKRRSGELVPLSEQNLLDCSRPEGTEGCGGGWMDDAFQYVLDQGGIDSESDYPYTATDVDSCHYDPSRMVARISGFVDIHKGSEKDLITAVASVGPVSVAIDAGHQSFQLYESGIYYEPECNCTELDHAVLVVGFGVKGRGENGKKFWIVKNRRGLQCGGEIYLEVAVDKRCFCGLYQIMNVTL 346
BLAST of Cathepsin L2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000003800.1 (pep scaffold:Pmarinus_7.0:GL485125:12828:20107:1 gene:ENSPMAG00000003453.1 transcript:ENSPMAT00000003800.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 315.079 bits (806), Expect = 3.602e-107 Identity = 164/292 (56.16%), Postives = 202/292 (69.18%), Query Frame = 3 Query: 204 RRLIWEQNLKYIQQHNLEHDLGKHTYTLGLNHFADMTNEEFRANYLGVSPKRMNFTSH------FIAPENVGALPSSVDWRTKGFVTPVKNQQQCGSCWSFSTTGSLEGQHYRKTQNLISFSEQQLVDCSGSFGNNGCDGGLMDSAFQYIQQY-GIEAESTYPYTAQD-GNCVYDKSKVVGSCTGFSDIPHGNEQALASAVATVGPISVAIDASNYSFQLYKSGIYNEPQCSSSQLDHGVLAIGYGT-ENGKNFWLVKNSWGIGWGIQGYIKMSKDQGNQCGISTMASYPLV 1052 RR+IWEQNLK I HNLEH +GKHT+ +G+N F DMT EEF+ LG + N TS F+AP A P SVDWR +G+VT VKNQ CGSCWSFSTTGSLEGQH RKT L+S SEQ LVDCS + GN GC+GGLM +AF YI++ GI++E +YPY Q C Y+ TG+ +IP G+E+AL +AVA+VGP+SVAIDAS SF Y SGIY + CS ++H VL +GYG E G FWLVKNSWG+ WG +GY++M++D N CGI+ ASYPLV Sbjct: 8 RRMIWEQNLKKIAVHNLEHSMGKHTWRMGMNRFGDMTGEEFQQVMLGF--RGWNGTSKAPRGATFMAPAFFEA-PESVDWRKQGYVTDVKNQGDCGSCWSFSTTGSLEGQHKRKTGVLVSLSEQNLVDCSSTEGNYGCNGGLMINAFNYIKKNGGIDSEESYPYKGQGVETCKYNPKNKAAEVTGYVEIPEGDEEALKNAVASVGPVSVAIDASLNSFLYYISGIYKDKLCSHI-INHAVLVVGYGVDEKGDKFWLVKNSWGVQWGEKGYVRMARDDNNLCGIAVTASYPLV 295
BLAST of Cathepsin L2 vs. Ensembl Nematostella
Match: EDO46465 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RPY5]) HSP 1 Score: 370.933 bits (951), Expect = 2.455e-128 Identity = 179/311 (57.56%), Postives = 227/311 (72.99%), Query Frame = 3 Query: 129 SEL--NDEWEAYKTQFGKKYVSLNEISRRLIWEQNLKYIQQHNLEHDLGKHTYTLGLNHFADMTNEEFRANYLGVSPKRMNFTSHFIAPENVGALPSSVDWRTKGFVTPVKNQQQCGSCWSFSTTGSLEGQHYRKTQNLISFSEQQLVDCSGSFGNNGCDGGLMDSAFQYIQQY-GIEAESTYPYTAQDGNCVYDKSKVVGSCTGFSDIPHGNEQALASAVATVGPISVAIDASNYSFQLYKSGIYNEPQCSSSQLDHGVLAIGYGTENGKNFWLVKNSWGIGWGIQGYIKMSKDQGNQCGISTMASYPLV 1052 SEL + +W A+K GK Y E RR IW NL+ +++HN E+ H+Y L +NHFAD+T EF+ ++G + P + LP+ VDWR KGFVT VKNQ QCGSCW+FS+TGSLEGQH+RKT L+S SEQ LVDCS +GNNGC+GGLMD AF+YI+ GI+ E +YPYTA+DG C + V + TG++D+ G+E L SAVATVGPISVAIDA + SFQLYK+G+Y+EP CSS+QLDHGVLA+GYG E+GK++WLVKNSWG GWG+ GYIKMS+++ NQCGI+T ASYPLV Sbjct: 19 SELSQDRQWHAWKDFHGKTYTGEEEDLRRAIWNDNLEIVKKHNAEN----HSYKLDMNHFADLTVTEFKQRFMGYRAASNSTGGSTFLPLSNVQLPAEVDWRDKGFVTAVKNQGQCGSCWAFSSTGSLEGQHFRKTGKLVSLSEQNLVDCSKKYGNNGCEGGLMDYAFKYIKNNDGIDTEQSYPYTARDGQCHFKPGSVGATVTGYTDVQRGSEGDLQSAVATVGPISVAIDAGHSSFQLYKTGVYSEPDCSSTQLDHGVLAVGYGAEDGKDYWLVKNSWGEGWGMNGYIKMSRNKDNQCGIATQASYPLV 325
BLAST of Cathepsin L2 vs. Ensembl Nematostella
Match: EDO45953 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RRH6]) HSP 1 Score: 361.688 bits (927), Expect = 9.597e-125 Identity = 180/312 (57.69%), Postives = 231/312 (74.04%), Query Frame = 3 Query: 138 NDEWEAYKTQFGKKYVSLNEISRRL-IWEQNLKYIQQHNLEHDLGKHTYTLGLNHFADMTNEEFRANYLGV-----SPKRMNFTSHFIAPENVGALPSSVDWRTKGFVTPVKNQQQCGSCWSFSTTGSLEGQHYRKTQNLISFSEQQLVDCSGSFGNNGCDGGLMDSAFQYIQQY-GIEAESTYPYTAQDGNCVYDKSKVVGSCTGFSDIPHGNEQALASAVATVGPISVAIDASNYSFQLYKSGIYNEPQCSSSQLDHGVLAIGYGTENGKNFWLVKNSWGIGWGIQGYIKMSKDQGNQCGISTMASYPLV 1052 + EW A+K+ GK Y ++E R+ IW+QNL+ I++HN E H+Y + +NH D+T +EFR YLGV S KR T ++ P NV +PSSVDW KG+VT VKNQ QCGSCW+FSTTGS+EGQH+RKT +L+S SEQ L+DCSGS+GNNGC GGLMD+AF+YI+ GI+ ES+YPY Q G+C + S V TG+ DIP G+EQAL SAVATVGP+SVA+DAS + Q Y SG+Y+ P CSS+QLDHGVL IGYG NG+++WLVKNSWG WG++GYI MS+++ NQCGI++ ASYPLV Sbjct: 24 DSEWVAWKSYHGKSYSDVHEERTRMAIWQQNLEKIKRHNAE----DHSYKMAMNHLGDLTEDEFRYFYLGVRAHHNSTKRGWAT--YMPPSNV-KIPSSVDWSQKGYVTGVKNQGQCGSCWAFSTTGSVEGQHFRKTGSLVSLSEQNLIDCSGSYGNNGCQGGLMDNAFRYIESNGGIDTESSYPYLGQQGSCHFSSSHVGARVTGYQDIPQGSEQALQSAVATVGPVSVAVDASQW--QFYSSGVYDNPYCSSTQLDHGVLVIGYGNYNGQDYWLVKNSWGYSWGVEGYIMMSRNKNNQCGIASSASYPLV 326
BLAST of Cathepsin L2 vs. Ensembl Nematostella
Match: EDO45852 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RRL9]) HSP 1 Score: 357.836 bits (917), Expect = 4.252e-123 Identity = 170/308 (55.19%), Postives = 229/308 (74.35%), Query Frame = 3 Query: 147 WEAYKTQFGKKYVSLNEIS-RRLIWEQNLKYIQQHNLEHDLGKHTYTLGLNHFADMTNEEFRANYLGVSPKRMNFT----SHFIAPENVGALPSSVDWRTKGFVTPVKNQQQCGSCWSFSTTGSLEGQHYRKTQNLISFSEQQLVDCSGSFGNNGCDGGLMDSAFQYIQQYG-IEAESTYPYTAQDGNCVYDKSKVVGSCTGFSDIPHGNEQALASAVATVGPISVAIDASNYSFQLYKSGIYNEPQCSSSQLDHGVLAIGYGTENGKNFWLVKNSWGIGWGIQGYIKMSKDQGNQCGISTMASYPLV 1052 W+A+K+ GK+Y + NE + R IW+ NLK I HN GKH++ L +NH DMT+ E LG+ K+ + + F+ P NV + S+DWR+KG+VTPVKNQ QCGSCW+FSTTG+LEGQH+RKT L+S SEQ LVDCSG +GNNGC+GGLMD+AFQYI++ G I+ E +YPY A+DG C Y+KS + TGF DIP G+E AL A+A+VGPIS+AIDAS +F Y G+Y++P CSS++LDHGVLA+GYGT++GK++WLVKNSWG WG +GYIK++++ ++CG+++ ASYPLV Sbjct: 29 WKAWKSFHGKEYPNKNEETMRNFIWQNNLKKIVTHNE----GKHSFKLAMNHLGDMTSLEISQTLLGLKLKKHAESQPKGATFLPPANVKVV-DSIDWRSKGYVTPVKNQGQCGSCWAFSTTGALEGQHFRKTGKLVSLSEQNLVDCSGKYGNNGCEGGLMDNAFQYIKENGGIDTEKSYPYLAKDGVCHYNKSAIGAKDTGFVDIPTGDENALQQALASVGPISIAIDASQSTFHFYHQGVYDDPDCSSTRLDHGVLAVGYGTDDGKDYWLVKNSWGPSWGEEGYIKIARNDHDKCGVASKASYPLV 331
BLAST of Cathepsin L2 vs. Ensembl Nematostella
Match: EDO36727 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SHX1]) HSP 1 Score: 356.681 bits (914), Expect = 9.110e-123 Identity = 172/313 (54.95%), Postives = 226/313 (72.20%), Query Frame = 3 Query: 132 ELNDEWEAYKTQFGKKYVSLNEI-SRRLIWEQNLKYIQQHNLEHDLGKHTYTLGLNHFADMTNEEFRANYLGVSPKRMNFT----SHFIAPENVGALPSSVDWRTKGFVTPVKNQQQCGSCWSFSTTGSLEGQHYRKTQNLISFSEQQLVDCSGSFGNNGCDGGLMDSAFQYIQQYG-IEAESTYPYTAQDGNCVYDKSKVVGSCTGFSDIPHGNEQALASAVATVGPISVAIDASNYSFQLYKSGIYNEPQCSSSQLDHGVLAIGYGTENGKNFWLVKNSWGIGWGIQGYIKMSKDQGNQCGISTMASYPLV 1052 E +W+A+K KKY ++ E +R+ IW NLK IQ+HN E H++TL +NH D+T +EFR Y G+ N+T S F+AP +V +P +VDWR +G+VTPVKNQ QCGSCW+FSTTGSLEGQ+++KT L+S SEQ LVDCS ++GNNGC GGLMD AF+YI++ G I+ E +YPY A++ C + KS + TGF D+ HG+E+AL +A TVGPISVAIDA + SFQ Y SG+YN CSS+ LDHGVL +GYGT G ++WLVKNSWG WG++GYI MS+++ NQCG++T ASYPLV Sbjct: 23 EDEQQWQAWKLFHTKKYTTVTEEGARKAIWRDNLKKIQKHNAE----GHSFTLAMNHLGDLTQDEFRYFYTGMRSHYSNYTKKQGSAFLAPSHV-QVPDTVDWRKEGYVTPVKNQGQCGSCWAFSTTGSLEGQNFKKTGKLVSLSEQNLVDCSTAYGNNGCQGGLMDYAFKYIKENGGIDTEESYPYEARNDRCRFQKSNIGAVDTGFVDVTHGDEEALKTAAGTVGPISVAIDAGHMSFQFYHSGVYNNAGCSSTSLDHGVLVVGYGTYQGSDYWLVKNSWGERWGMEGYIMMSRNKNNQCGVATQASYPLV 330
BLAST of Cathepsin L2 vs. Ensembl Nematostella
Match: EDO41322 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S4P4]) HSP 1 Score: 228.024 bits (580), Expect = 7.033e-70 Identity = 121/296 (40.88%), Postives = 175/296 (59.12%), Query Frame = 3 Query: 201 SRRLIWEQNLKYIQQHNLEHDLGKHTYTLGLNHFADMTNEEFRA--------NYLGVSPKRMNFTSHFIAPENVGALPSSVDWRTKGFVTPVKNQQQCGSCWSFSTTGSLEGQHYRKTQNLISFSEQQLVDCSGSFGNNGCDGGLMDSAFQYIQQY-GIEAESTY-PYTAQDGNCVYDKSKVVGSCTGFSDIPHGNEQALASAVATVGPISVAIDASNYSFQLYKSGIYNEPQC--SSSQLDHGVLAIGYGTENGKNFWLVKNSWGIGWGIQGYIKMSKDQGNQCGISTMASYPLV 1052 +RR ++ NL++I N H Y L +NH D +++E R Y G P + + S + +P ++W +G VTPVK+Q CGSCWSF TTG++EG + KT+ L S+Q L+DCS GNN CDGG ++QYI + GI E +Y PY DG C +++ + TG+ +I G+ AL +A+A GPISV+IDAS+ S Y G+Y EP+C + LDH VLA+GYGT +GK +W++KNSW WG+ GY+ MS+ + N CG++T A+Y L+ Sbjct: 264 TRREHFKHNLRFIHSKNRRH----AGYYLAMNHLGDRSDKELRVLRGRRYTKGYNGGLPYKPDMAS-------INDVPDEMNWVIRGAVTPVKDQAVCGSCWSFGTTGTIEGTLFLKTKYLTRLSQQNLMDCSWGEGNNACDGGEDFRSYQYIMKSGGIATEESYGPYLGADGYCHKKDAEIGATITGYVNITEGDLSALKTAIAQKGPISVSIDASHKSLSFYSYGVYYEPKCGNKNEDLDHSVLAVGYGTMDGKPYWMIKNSWSTHWGMNGYVLMSQ-KDNNCGVATAATYVLM 547
BLAST of Cathepsin L2 vs. Ensembl Medaka
Match: ctsl.1 (cathepsin L1 [Source:NCBI gene;Acc:101171789]) HSP 1 Score: 369.777 bits (948), Expect = 3.142e-127 Identity = 180/313 (57.51%), Postives = 229/313 (73.16%), Query Frame = 3 Query: 144 EWEAYKTQFGKKYVS-LNEISRRLIWEQNLKYIQQHNLEHDLGKHTYTLGLNHFADMTNEEFR--------ANYLGVSPKRMNFTSHFIAPENVGALPSSVDWRTKGFVTPVKNQQQCGSCWSFSTTGSLEGQHYRKTQNLISFSEQQLVDCSGSFGNNGCDGGLMDSAFQYIQQYG-IEAESTYPYTAQDGNCVYDKSKVVGSCTGFSDIPHGNEQALASAVATVGPISVAIDASNYSFQLYKSGIYNEPQCSSSQLDHGVLAIGYGTENGKNFWLVKNSWGIGWGIQGYIKMSKDQGNQCGISTMASYPLV 1052 E+ A++ +FG+ Y S E RR W N K + HN+ D G +Y LG+ +FADM NEE++ ++ P+R ++ F PEN LP++VDWR KG+VT VK+Q+QCGSCW+FS TGSLEGQ +RKT L+S SEQQLVDCSG +GN GC GGLMD AF+YIQ G I+ E +YPY A+DG C Y V +CTG+ D+ G+E AL AVAT+GPISV IDAS+ SFQLY+SG+Y+EPQCSSS+LDHGVLA+GYG+ENG+++WLVKNSWG+ WG QGYIKMSK++ NQCGI+T ASYPLV Sbjct: 30 EFHAWRLKFGRTYSSPTEEAQRRQTWLNNRKLVLVHNILADQGIKSYRLGMTYFADMENEEYKRLISQGCLGSFNASLPRRG--STFFRLPENKD-LPAAVDWRDKGYVTDVKDQKQCGSCWAFSATGSLEGQTFRKTGKLVSLSEQQLVDCSGDYGNMGCGGGLMDDAFRYIQATGGIDTEESYPYEAEDGECRYKPDAVGATCTGYVDVSSGDEDALQEAVATIGPISVGIDASHISFQLYESGLYDEPQCSSSELDHGVLAVGYGSENGQDYWLVKNSWGLTWGDQGYIKMSKNKSNQCGIATAASYPLV 339
BLAST of Cathepsin L2 vs. Ensembl Medaka
Match: ctsl (cathepsin L [Source:NCBI gene;Acc:100049246]) HSP 1 Score: 348.206 bits (892), Expect = 7.616e-119 Identity = 174/319 (54.55%), Postives = 221/319 (69.28%), Query Frame = 3 Query: 120 TINSELNDEWEAYKTQFGKKYVSLNEISRRLIWEQNLKYIQQHNLEHDLGKHTYTLGLNHFADMTNEEFR--ANYLGVSPKRMNFTSHFIAPENVGALPSSVDWRTKGFVTPVKNQQQCGSCWSFSTTGSLEGQHYRKTQNLISFSEQQLVDCSGSFGNNGCDGGLMDSAFQYIQQ-YGIEAESTYPYTAQDGN-CVYDKSKVVGSCTGFSDIPHGNEQALASAVATVGPISVAIDASNYSFQLYKSGIYNEPQCSSSQLDHGVLAIGYGTE----NGKNFWLVKNSWGIGWGIQGYIKMSKDQGNQCGISTMASYPLV 1052 T++ +L+ W+ +K K Y E RRL+WE+NL+ I+ HNLEH +GKH+Y LG+NHF DMT+EEFR N +R S F+ P N P +VDWR KG+VTPVK+Q QCGSCW+FSTTG+LEGQ +RKT L+S SEQ LVDCS GN GC+GGLMD AFQY++ G+++E YPY D C Y+ + TGF DIP G E+AL AVA+VGP+SVAIDA + SFQ Y+SGIY E +CSS +LDHGVL +GYG E +GK +W+VKNSW WG +G+I M+KD+ N CGI+T ASYPLV Sbjct: 19 TLDPQLDQHWQLWKGWHSKNYHEKEEGWRRLVWEKNLRKIELHNLEHSMGKHSYRLGMNHFGDMTHEEFRQIMNGYKRREQRKYSGSLFMEP-NFLEAPRAVDWRDKGYVTPVKDQGQCGSCWAFSTTGALEGQQFRKTGKLVSLSEQNLVDCSRPEGNEGCNGGLMDQAFQYVKDNQGLDSEDFYPYKGTDDQPCQYNAQYSAVNDTGFVDIPSGKERALMKAVASVGPVSVAIDAGHESFQFYQSGIYFEKECSSDELDHGVLVVGYGFEGEDVDGKKYWIVKNSWSEKWGDKGFIYMAKDRHNHCGIATAASYPLV 336
BLAST of Cathepsin L2 vs. Ensembl Medaka
Match: ctss (cathepsin S [Source:NCBI gene;Acc:100049247]) HSP 1 Score: 298.13 bits (762), Expect = 2.838e-99 Identity = 148/314 (47.13%), Postives = 201/314 (64.01%), Query Frame = 3 Query: 120 TINSELNDEWEAYKTQFGKKYV-SLNEISRRLIWEQNLKYIQQHNLEHDLGKHTYTLGLNHFADMTNEEFRANYLG-VSPKRMNFTSHFIAPENVGALPSSVDWRTKGFVTPVKNQQQCGSCWSFSTTGSLEGQHYRKTQNLISFSEQQLVDCSGSFGNNGCDGGLMDSAFQY-IQQYGIEAESTYPYTAQDGNCVYDKSKVVGSCTGFSDIPHGNEQALASAVATVGPISVAIDASNYSFQLYKSGIYNEPQCSSSQLDHGVLAIGYGTENGKNFWLVKNSWGIGWGIQGYIKMSKDQGNQCGISTMASYPLV 1052 + S L+ W +K + K Y + E RR IWE+NL+ I HNLE LG H+Y L +NH D+T EE A+ G V+P + + + N ++P SVDWR G VT VK Q +CGSCW+FS G+LEGQ + T L S S Q LVDCS +GN GC GG M +AFQY I+ GI +++ YPY + C YD +CTG++ +P G+E AL VAT+GPISVAIDAS F Y+ G+Y + CS + ++HGVL +GYGTENG+++WLVKNSWG +G GYIKM++++ NQCGI+ A +P++ Sbjct: 16 AVRSHLDQHWNLWKKTYSKTYSHEIEEFGRRRIWEENLEMISVHNLEVSLGLHSYELAMNHLGDLTIEELIASLTGTVAPVGLERIHYDLVKINT-SVPESVDWREGGLVTSVKTQGRCGSCWAFSAVGALEGQLKKTTGILTSLSPQNLVDCSTKYGNYGCKGGFMSNAFQYVIKNQGISSDAAYPYIGKRDKCKYDSKHRAANCTGYNFLPKGDEFALKVGVATIGPISVAIDASRPKFLFYRHGVYKDHSCSHN-VNHGVLVVGYGTENGEDYWLVKNSWGERYGDGGYIKMARNRRNQCGIALYACFPVM 327
BLAST of Cathepsin L2 vs. Ensembl Medaka
Match: ctss2.1 (cathepsin S [Source:NCBI gene;Acc:101165175]) HSP 1 Score: 296.975 bits (759), Expect = 1.009e-98 Identity = 144/315 (45.71%), Postives = 199/315 (63.17%), Query Frame = 3 Query: 120 TINSELNDEWEAYKTQFGKKYVSLNE-ISRRLIWEQNLKYIQQHNLEHDLGKHTYTLGLNHFADMTNEEFRANYLGVSPK-RMNFTSH-FIAPENVGALPSSVDWRTKGFVTPVKNQQQCGSCWSFSTTGSLEGQHYRKTQNLISFSEQQLVDCSGSFGNNGCDGGLMDSAFQY-IQQYGIEAESTYPYTAQDGNCVYDKSKVVGSCTGFSDIPHGNEQALASAVATVGPISVAIDASNYSFQLYKSGIYNEPQCSSSQLDHGVLAIGYGTENGKNFWLVKNSWGIGWGIQGYIKMSKDQGNQCGISTMASYPLV 1052 +S L+ WE +K K Y S E + RR +WE+NL I HNLE+ +G HTY L +NH D+T EE + + P + H F+ +P +DWR K VT VK Q CGSCW+FS G+LEGQ RKT L+ S Q LVDCS +GN+GC+GG M AFQY I GI++++ YPY NC Y +C+ +S +P G+E AL A+AT+GPISVAIDA+ F Y+SG+Y++ CS + ++HGVLA+GYGT NG+++WLVKNSWG +G QGYI+M++++ +QCGI+ YP++ Sbjct: 26 AFDSRLDIHWELWKKTHSKHYPSEEEDVHRRDLWERNLMLITMHNLEYSMGLHTYDLSMNHMGDLTQEEILQQFASLRPPTNLKREPHLFVGASGSNNIPDEMDWRQKNCVTSVKMQGSCGSCWAFSAVGALEGQLCRKTGKLVDLSPQNLVDCSSKYGNHGCNGGFMHQAFQYVIDNQGIDSDAGYPYVGVTQNCHYSSEYRAANCSQYSFLPEGDEGALKEAIATIGPISVAIDATRPRFAFYRSGVYDDSSCSQN-VNHGVLAVGYGTLNGQDYWLVKNSWGTTFGEQGYIRMARNKNDQCGIAMYGCYPIM 339
BLAST of Cathepsin L2 vs. Ensembl Medaka
Match: ctsk (cathepsin K [Source:NCBI gene;Acc:101164922]) HSP 1 Score: 292.352 bits (747), Expect = 5.103e-97 Identity = 148/315 (46.98%), Postives = 202/315 (64.13%), Query Frame = 3 Query: 129 SELNDEWEAYKTQFGKKYVSLNEIS-RRLIWEQNLKYIQQHNLEHDLGKHTYTLGLNHFADMTNEEFRANYLGVSPKRMNFTSHFIAP-ENVGAL---PSSVDWRTKGFVTPVKNQQQCGSCWSFSTTGSLEGQHYRKTQNLISFSEQQLVDCSGSFGNNGCDGGLMDSAFQYIQQYG-IEAESTYPYTAQDGNCVYDKSKVVGSCTGFSDIPHGNEQALASAVATVGPISVAIDASNYSFQLYKSGIYNEPQCSSSQLDHGVLAIGYGTE-NGKNFWLVKNSWGIGWGIQGYIKMSKDQGNQCGISTMASYPLV 1052 + L+ WE +K K+Y+++ E RR IWE+NL+ I+ HN E LG HTYTLG+N F DMT EE G+ +M P E G+L P SVD+R KG VT VKNQ CGSCW+FS+ G+LEGQ +KT NL+ S Q LVDC N+GC GG M +AF+Y+Q+ G I++E+ YPY +D C Y+ S + G+ ++P G+E ALA A+ GP+SV IDAS SF Y+ GIY + C+ ++H VLA+GYG GK FW+VKNSWG WG +GY+ M++++GN CGI+ +ASYP++ Sbjct: 22 TTLDAHWEEWKMTHTKEYITVEEEGIRRAIWEKNLRMIEAHNQEAALGMHTYTLGMNQFGDMTQEEVVERMTGL---QMPLNPEPRVPMETDGSLIKLPKSVDYRKKGMVTSVKNQGSCGSCWAFSSVGALEGQLAKKTGNLVDLSPQNLVDCVTE--NDGCGGGYMTNAFKYVQENGGIDSEAAYPYMGEDQPCRYNVSGLAAQIKGYKEVPEGDEHALAVALFKAGPVSVGIDASQNSFLYYQKGIYFDRNCNKEDINHAVLAVGYGVNAKGKKFWIVKNSWGETWGNKGYVLMARNRGNVCGIANLASYPVM 331
BLAST of Cathepsin L2 vs. Planmine SMEST
Match: SMESG000049723.1 (SMESG000049723.1) HSP 1 Score: 665.996 bits (1717), Expect = 0.000e+0 Identity = 331/332 (99.70%), Postives = 332/332 (100.00%), Query Frame = 3 Query: 57 MQIIIXXXXXXXXXXXXPQQFTINSELNDEWEAYKTQFGKKYVSLNEISRRLIWEQNLKYIQQHNLEHDLGKHTYTLGLNHFADMTNEEFRANYLGVSPKRMNFTSHFIAPENVGALPSSVDWRTKGFVTPVKNQQQCGSCWSFSTTGSLEGQHYRKTQNLISFSEQQLVDCSGSFGNNGCDGGLMDSAFQYIQQYGIEAESTYPYTAQDGNCVYDKSKVVGSCTGFSDIPHGNEQALASAVATVGPISVAIDASNYSFQLYKSGIYNEPQCSSSQLDHGVLAIGYGTENGKNFWLVKNSWGIGWGIQGYIKMSKDQGNQCGISTMASYPLV 1052 MQIIILVSLFLAAVSAAPQQFTINSELNDEWEAYKTQFGKKYVSLNEISRRLIWEQNLKYIQQHNLEHDLGKHTYTLGLNHFADMTNEEFRANYLGVSPKRMNFTSHFIAPENVGALPSSVDWRTKGFVTPVKNQQQCGSCWSFSTTGSLEGQHYRKTQNLISFSEQQLVDCSGSFGNNGCDGGLMDSAFQYIQQYGIEAESTYPYTAQDGNCVYDKSKVVGSCTGFSDIPHGNEQALASAVATVGPISVAIDASNYSFQLYKSGIYNEPQCSSSQLDHGVLAIGYGTENGKNFWLVKNSWGIGWGIQGYIKMSKDQGNQCGI+TMASYPLV Sbjct: 1 MQIIILVSLFLAAVSAAPQQFTINSELNDEWEAYKTQFGKKYVSLNEISRRLIWEQNLKYIQQHNLEHDLGKHTYTLGLNHFADMTNEEFRANYLGVSPKRMNFTSHFIAPENVGALPSSVDWRTKGFVTPVKNQQQCGSCWSFSTTGSLEGQHYRKTQNLISFSEQQLVDCSGSFGNNGCDGGLMDSAFQYIQQYGIEAESTYPYTAQDGNCVYDKSKVVGSCTGFSDIPHGNEQALASAVATVGPISVAIDASNYSFQLYKSGIYNEPQCSSSQLDHGVLAIGYGTENGKNFWLVKNSWGIGWGIQGYIKMSKDQGNQCGIATMASYPLV 332
BLAST of Cathepsin L2 vs. Planmine SMEST
Match: SMESG000014166.1 (SMESG000014166.1) HSP 1 Score: 505.368 bits (1300), Expect = 0.000e+0 Identity = 230/313 (73.48%), Postives = 274/313 (87.54%), Query Frame = 3 Query: 117 FTINSELNDEWEAYKTQFGKKYVSLNEISRRLIWEQNLKYIQQHNLEHDLGKHTYTLGLNHFADMTNEEFRANYLG-VSPKRMNFTSHFIAPENVGALPSSVDWRTKGFVTPVKNQQQCGSCWSFSTTGSLEGQHYRKTQNLISFSEQQLVDCSGSFGNNGCDGGLMDSAFQYIQQYGIEAESTYPYTAQDGNCVYDKSKVVGSCTGFSDIPHGNEQALASAVATVGPISVAIDASNYSFQLYKSGIYNEPQCSSSQLDHGVLAIGYGTENGKNFWLVKNSWGIGWGIQGYIKMSKDQGNQCGISTMASYPLV 1052 F++NSELN++WE YKTQF ++Y L EI+RR+IWEQNL+YI+QHNLE+DLGKHTY LGLN +AD+TNEEF+A +LG + + S F+APEN+GALP++VDWRTKG+VTPVKNQQQCGSCW+FSTTGSLEGQH+RKT +L+SFSEQQLVDCSG++GN GC GGLMD+AF YI +YG+E+E YPYTA DG C YD+SKVVG+C+GF+DI HGNE LA AVATVGP+SVAIDAS+YSFQLYK GIYNEPQCS QLDHGVLA+GYG+ENG N+WLVKNSWGI WG+ GYIKMSKD+ NQCGIST AS+PLV Sbjct: 22 FSLNSELNEDWELYKTQFKRQYEPLTEITRRIIWEQNLEYIRQHNLEYDLGKHTYYLGLNEYADLTNEEFKAKFLGKILTRSSTKGSQFMAPENMGALPTTVDWRTKGYVTPVKNQQQCGSCWAFSTTGSLEGQHFRKTGSLVSFSEQQLVDCSGAYGNEGCGGGLMDNAFNYIMKYGLESERDYPYTATDGKCKYDRSKVVGTCSGFTDIKHGNESDLAVAVATVGPVSVAIDASHYSFQLYKGGIYNEPQCSPDQLDHGVLAVGYGSENGGNYWLVKNSWGISWGLSGYIKMSKDRKNQCGISTSASFPLV 334
BLAST of Cathepsin L2 vs. Planmine SMEST
Match: SMESG000014167.1 (SMESG000014167.1) HSP 1 Score: 504.212 bits (1297), Expect = 1.431e-180 Identity = 230/313 (73.48%), Postives = 273/313 (87.22%), Query Frame = 3 Query: 117 FTINSELNDEWEAYKTQFGKKYVSLNEISRRLIWEQNLKYIQQHNLEHDLGKHTYTLGLNHFADMTNEEFRANYLG-VSPKRMNFTSHFIAPENVGALPSSVDWRTKGFVTPVKNQQQCGSCWSFSTTGSLEGQHYRKTQNLISFSEQQLVDCSGSFGNNGCDGGLMDSAFQYIQQYGIEAESTYPYTAQDGNCVYDKSKVVGSCTGFSDIPHGNEQALASAVATVGPISVAIDASNYSFQLYKSGIYNEPQCSSSQLDHGVLAIGYGTENGKNFWLVKNSWGIGWGIQGYIKMSKDQGNQCGISTMASYPLV 1052 F++NSELN +WE YKTQF ++Y L EI+RR+IWEQNL+YI+QHNLE+DLGKHTY LGLN +AD+TNEEF+A +LG + + S F+APEN+GALP++VDWRTKG+VTPVKNQQQCGSCW+FSTTGSLEGQH+RKT +L+SFSEQQLVDCSG++GN GC GGLMD+AF YI +YG+E+E YPYTA DG C YD+SKVVG+C+GF+DI HGNE LA AVATVGP+SVAIDAS+YSFQLYK GIYNEPQCS QLDHGVLA+GYG+ENG N+WLVKNSWGI WG+ GYIKMSKD+ NQCGIST AS+PLV Sbjct: 21 FSLNSELNKDWELYKTQFKRQYEPLTEITRRIIWEQNLEYIRQHNLEYDLGKHTYYLGLNEYADLTNEEFKAKFLGKILTRSSRKGSQFMAPENMGALPTTVDWRTKGYVTPVKNQQQCGSCWAFSTTGSLEGQHFRKTGSLVSFSEQQLVDCSGAYGNEGCGGGLMDNAFNYIMKYGLESERDYPYTATDGKCKYDRSKVVGTCSGFTDIKHGNESDLAVAVATVGPVSVAIDASHYSFQLYKGGIYNEPQCSPDQLDHGVLAVGYGSENGGNYWLVKNSWGISWGLSGYIKMSKDRNNQCGISTSASFPLV 333
BLAST of Cathepsin L2 vs. Planmine SMEST
Match: SMESG000049722.1 (SMESG000049722.1) HSP 1 Score: 476.093 bits (1224), Expect = 1.922e-169 Identity = 226/333 (67.87%), Postives = 269/333 (80.78%), Query Frame = 3 Query: 57 MQIIIXXXXXXXXXXXXPQQFTINSELNDEWEAYKTQFGKKYVSLNEISRRLIWEQNLKYIQQHNLEHDLGKHTYTLGLNHFADMTNEEFRANYLGVSPKRMNFT-SHFIAPENVGALPSSVDWRTKGFVTPVKNQQQCGSCWSFSTTGSLEGQHYRKTQNLISFSEQQLVDCSGSFGNNGCDGGLMDSAFQYIQQYGIEAESTYPYTAQDGNCVYDKSKVVGSCTGFSDIPHGNEQALASAVATVGPISVAIDASNYSFQLYKSGIYNEPQCSSSQLDHGVLAIGYGTENGKNFWLVKNSWGIGWGIQGYIKMSKDQGNQCGISTMASYPLV 1052 M+I++L + ++SA +F +N LN+EW YK QF +KY S+ E++RRLIWE+NL+ IQ+HN+E+DLGKH+Y LGLN FADMTNEE+R LG+ P N+T + F+APEN LP SVDWRTKG+VTPVKNQ CGSCWSFSTTGSLEGQH RKT LIS SEQQLVDCS FGNNGC+GGLMD+AFQYIQ+YG+E+E+ Y YTA++GNC YD SKVV CTGF DI GNE+ LA AVATVGPISVAIDAS +FQLYK GIYNE CSS QLDHGVLA+GYG EN ++FW+VKNSWG WG+ GYIKM+KD+ NQCGI+TMASYPLV Sbjct: 1 MKIVLLAVFCVVSISAGKLKFEVNEALNEEWNMYKIQFQRKYESIIELTRRLIWEENLRLIQKHNIEYDLGKHSYYLGLNEFADMTNEEYRVKVLGLKPINKNYTRTIFLAPENTVDLPKSVDWRTKGYVTPVKNQANCGSCWSFSTTGSLEGQHKRKTGQLISLSEQQLVDCSKPFGNNGCNGGLMDNAFQYIQKYGLESEADYSYTAKEGNCKYDASKVVAHCTGFVDIKKGNEKDLAKAVATVGPISVAIDASKPTFQLYKGGIYNEKSCSSRQLDHGVLAVGYGKENNQHFWIVKNSWGPQWGLSGYIKMTKDRHNQCGIATMASYPLV 333
BLAST of Cathepsin L2 vs. Planmine SMEST
Match: SMESG000014171.1 (SMESG000014171.1) HSP 1 Score: 420.624 bits (1080), Expect = 1.778e-147 Identity = 204/336 (60.71%), Postives = 257/336 (76.49%), Query Frame = 3 Query: 57 MQIIIXXXXXXXXXXXXPQQFTINSELNDEWEAYKTQFGKKYVSLNEISRRLIWEQNLKYIQQHNLEHDLGKHTYTLGLNHFADMTNEEFRANYLGVSPKRMNFT----SHFIAPENVGALPSSVDWRTKGFVTPVKNQQQCGSCWSFSTTGSLEGQHYRKTQNLISFSEQQLVDCSGSFGNNGCDGGLMDSAFQYIQQYGIEAESTYPYTAQDGNCVYDKSKVVGSCTGFSDIPHGNEQALASAVATVGPISVAIDASNYSFQLYKSGIYNEPQCSSSQLDHGVLAIGYGTENGKNFWLVKNSWGIGWGIQGYIKMSKDQGNQCGISTMASYPLV 1052 M+ I++SLFL A+ A P++FT+NSELN+EWE +K QF K+Y L E+ RR+IWE+NL +I+QHNLE+DLGKH+YTLGLN ++D+TN EF+A LG R+N + S F+ PEN+GALPSSVDWRTKG+VTPVKNQ CGSCW+FS TG+LEGQH+RKT LIS SEQQLVDCS +GN GC GG AF Y+ +YG+E+E Y Y ++ C+YDKSKVV + T ++ GNE LA+AVATVGP+S+ IDA + FQ YK+GIYN P CSS LDH VL +GYG+ NG N+W+VKNSWG WGI+GYI MSKD+ NQCGI+T A YP+V Sbjct: 1 MKAFIILSLFLVAIEAGPRRFTVNSELNEEWELFKAQFHKQYEPLTEVMRRIIWEENLDFIRQHNLEYDLGKHSYTLGLNEYSDLTNAEFKAKLLG---NRLNGSNSKGSEFMVPENIGALPSSVDWRTKGYVTPVKNQYTCGSCWAFSATGALEGQHFRKTGKLISLSEQQLVDCSRPYGNLGCGGGFPYQAFDYVNKYGMESEDDYIYRNKENKCIYDKSKVVANFTSYTFTKPGNESDLAAAVATVGPLSIGIDADHPGFQHYKNGIYNNPTCSSEYLDHAVLVVGYGSLNGNNYWIVKNSWGPHWGIEGYILMSKDKDNQCGIATQAVYPVV 333 The following BLAST results are available for this feature:
BLAST of Cathepsin L2 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Cathepsin L2 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Cathepsin L2 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Cathepsin L2 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Cathepsin L2 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Cathepsin L2 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Cathepsin L2 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Cathepsin L2 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Cathepsin L2 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Cathepsin L2 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Cathepsin L2 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of Cathepsin L2 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Cathepsin L2 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Cathepsin L2 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30018252 ID=SMED30018252|Name=Cathepsin L2|organism=Schmidtea mediterranea sexual|type=transcript|length=1107bpback to top protein sequence of SMED30018252-orf-1 >SMED30018252-orf-1 ID=SMED30018252-orf-1|Name=SMED30018252-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=333bp MQIIILVSLFLAAVSAAPQQFTINSELNDEWEAYKTQFGKKYVSLNEISRback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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