RFX-type winged-helix domain-containing protein

Overview


Name	RFX-type winged-helix domain-containing protein
Smed ID	SMED30018240
Length (bp)	1601

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of RFX-type winged-helix domain-containing protein (SMED30018240) t-SNE clustered cells

Violin plots show distribution of expression levels for RFX-type winged-helix domain-containing protein (SMED30018240) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of RFX-type winged-helix domain-containing protein (SMED30018240) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30018240

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 3

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
X1 cell	SMED30018240	SMESG000021065.1	SmedASXL_012986	SmedAsxl_ww_GCZZ01	PMID:26114597 Zhu et al., 2015
X2 cell	SMED30018240	SMESG000021065.1	SmedASXL_012986	SmedAsxl_ww_GCZZ01	PMID:26114597 Zhu et al., 2015
parapharyngeal region	SMED30018240	SMESG000021065.1	dd_Smed_v6_15486_0_1	dd_Smed_v6	PMID:28171748 Stückemann et al., 2017

Note: Hover over icons to view figure legend

Homology

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BLAST of RFX-type winged-helix domain-containing protein vs. Ensembl Human
Match: RFX5 (regulatory factor X5 [Source:HGNC Symbol;Acc:HGNC:9986])

HSP 1 Score: 112.849 bits (281), Expect = 2.810e-28
Identity = 66/166 (39.76%), Postives = 97/166 (58.43%), Query Frame = 3

Query:  318 LEKTLTEDKSTKVKEIISQILNLSDTEKLLIQLQFPMTESDNGTFDSSMNIGFNNVDILGNSTIVEQEE--ASKWVLSHLEENKTTCLQKQEVYEDYKSYCMTYNI-KCLSTADFGKVMKKNFPNIKARRLGARGQSRYCYSGLRNRQETQSPALKDIGMVLEGND 806
            L  T+++    KV+ I+  +   SD +KL + LQ P   S   T D S             ST+  +E   A +W+ +HLEE+  TCL KQ VY+ Y+ YC +    + LSTA+FGK++++ FP+IKARRLG RGQS+YCYSG+R +     P L   G+ L+G++
Sbjct:   34 LRGTISKAVQNKVEGILQDVQKFSDNDKLYLYLQLP---SGPTTGDKSSE----------PSTLSNEEYMYAYRWIRNHLEEHTDTCLPKQSVYDAYRKYCESLACCRPLSTANFGKIIREIFPDIKARRLGGRGQSKYCYSGIRRKTLVSMPPLP--GLDLKGSE 184

[Close]

BLAST of RFX-type winged-helix domain-containing protein vs. Ensembl Human
Match: RFX5 (regulatory factor X5 [Source:HGNC Symbol;Acc:HGNC:9986])

HSP 1 Score: 112.849 bits (281), Expect = 6.873e-28
Identity = 66/169 (39.05%), Postives = 99/169 (58.58%), Query Frame = 3

Query:  318 LEKTLTEDKSTKVKEIISQILNLSDTEKLLIQLQFPMTESDNGTFDSSMNIGFNNVDILGNSTIVEQEE--ASKWVLSHLEENKTTCLQKQEVYEDYKSYCMTYNI-KCLSTADFGKVMKKNFPNIKARRLGARGQSRYCYSGLRNRQETQSPALKDIGMVLEGNDTAD 815
            L  T+++    KV+ I+  +   SD +KL + LQ P   S   T D S             ST+  +E   A +W+ +HLEE+  TCL KQ VY+ Y+ YC +    + LSTA+FGK++++ FP+IKARRLG RGQS+YCYSG+R +     P L   G+ L+G+++ +
Sbjct:   34 LRGTISKAVQNKVEGILQDVQKFSDNDKLYLYLQLP---SGPTTGDKSSE----------PSTLSNEEYMYAYRWIRNHLEEHTDTCLPKQSVYDAYRKYCESLACCRPLSTANFGKIIREIFPDIKARRLGGRGQSKYCYSGIRRKTLVSMPPLP--GLDLKGSESPE 187

[Close]

BLAST of RFX-type winged-helix domain-containing protein vs. Ensembl Human
Match: RFX7 (regulatory factor X7 [Source:HGNC Symbol;Acc:HGNC:25777])

HSP 1 Score: 119.783 bits (299), Expect = 1.293e-27
Identity = 66/167 (39.52%), Postives = 93/167 (55.69%), Query Frame = 3

Query:  348 TKVKEIISQILNLSDTEKLLIQLQFPMTESDNGTFDSSMNIGFNNVDILGNSTIVEQEEASKWVLSHLEENKTTCLQKQEVYEDYKSYCMTYNIKCLSTADFGKVMKKNFPNIKARRLGARGQSRYCYSGLRNRQETQSPALKDI-----GMVLEGNDTADDYRKRD 833
            +KV  I+ ++   +D EKL + LQ P          S ++ G  +     +S+  +Q  A  W+ + LEE+  T L KQEVY++YKSYC       LS ADFGK+MK  FPN+KARRLG RG+S+YCYSGLR +     P L ++     G  LEG + +   +  D
Sbjct:   59 SKVDCILQEVEKFTDLEKLYLYLQLP----------SGLSNGEKSDQNAMSSSRAQQMHAFSWIRNTLEEHPETSLPKQEVYDEYKSYCDNLGYHPLSAADFGKIMKNVFPNMKARRLGTRGKSKYCYSGLRKKAFVHMPTLPNLDFHKTGDGLEGAEPSGQLQNID 215

[Close]

BLAST of RFX-type winged-helix domain-containing protein vs. Ensembl Human
Match: RFX5 (regulatory factor X5 [Source:HGNC Symbol;Acc:HGNC:9986])

HSP 1 Score: 117.857 bits (294), Expect = 2.276e-27
Identity = 77/251 (30.68%), Postives = 126/251 (50.20%), Query Frame = 3

Query:  318 LEKTLTEDKSTKVKEIISQILNLSDTEKLLIQLQFPMTESDNGTFDSSMNIGFNNVDILGNSTIVEQEE--ASKWVLSHLEENKTTCLQKQEVYEDYKSYCMTYNI-KCLSTADFGKVMKKNFPNIKARRLGARGQSRYCYSGLRNRQETQSPALKDIGMVLEGNDTADDYRKRDNVANSEVESYSSTSVLNNDLSNVPEYELSPNILIDSALVIIEFIKQVAMNKNIMSLKQAVKHLLSNSQVDMRSPHA 1061
            L  T+++    KV+ I+  +   SD +KL + LQ P   S   T D S             ST+  +E   A +W+ +HLEE+  TCL KQ VY+ Y+ YC +    + LSTA+FGK++++ FP+IKARRLG RGQS+YCYSG+R +     P L   G+ L+G+++ +                     +  +++  P  E     L+++A  +     +  + ++  S+ +  + LL    +  RS HA
Sbjct:   34 LRGTISKAVQNKVEGILQDVQKFSDNDKLYLYLQLP---SGPTTGDKSSE----------PSTLSNEEYMYAYRWIRNHLEEHTDTCLPKQSVYDAYRKYCESLACCRPLSTANFGKIIREIFPDIKARRLGGRGQSKYCYSGIRRKTLVSMPPLP--GLDLKGSESPE---------------------MGPEVTPAPRDE-----LVEAACALTCDWAERILKRSFSSIVEVARFLLQQHLISARSAHA 243

[Close]

Query:  318 LEKTLTEDKSTKVKEIISQILNLSDTEKLLIQLQFPMTESDNGTFDSSMNIGFNNVDILGNSTIVEQEE--ASKWVLSHLEENKTTCLQKQEVYEDYKSYCMTYNI-KCLSTADFGKVMKKNFPNIKARRLGARGQSRYCYSGLRNRQETQSPALKDIGMVLEGNDTADDYRKRDNVANSEVESYSSTSVLNNDLSNVPEYELSPNILIDSALVIIEFIKQVAMNKNIMSLKQAVKHLLSNSQVDMRSPHA 1061
            L  T+++    KV+ I+  +   SD +KL + LQ P   S   T D S             ST+  +E   A +W+ +HLEE+  TCL KQ VY+ Y+ YC +    + LSTA+FGK++++ FP+IKARRLG RGQS+YCYSG+R +     P L   G+ L+G+++ +                     +  +++  P  E     L+++A  +     +  + ++  S+ +  + LL    +  RS HA
Sbjct:   34 LRGTISKAVQNKVEGILQDVQKFSDNDKLYLYLQLP---SGPTTGDKSSE----------PSTLSNEEYMYAYRWIRNHLEEHTDTCLPKQSVYDAYRKYCESLACCRPLSTANFGKIIREIFPDIKARRLGGRGQSKYCYSGIRRKTLVSMPPLP--GLDLKGSESPE---------------------MGPEVTPAPRDE-----LVEAACALTCDWAERILKRSFSSIVEVARFLLQQHLISARSAHA 243

[Close]

BLAST of RFX-type winged-helix domain-containing protein vs. Ensembl Celegans
Match: daf-19 (RFX-like transcription factor daf-19 [Source:UniProtKB/Swiss-Prot;Acc:Q09555])

HSP 1 Score: 61.2326 bits (147), Expect = 1.244e-9
Identity = 26/70 (37.14%), Postives = 44/70 (62.86%), Query Frame = 3

Query:  534 WVLSHLEENKTTCLQKQEVYEDYKSYCMTYNIKCLSTADFGKVMKKNFPNIKARRLGARGQSRYCYSGLR 743
            W+  + E  + + L + E+Y+ YK +C  + +  ++ A FGK+++  F N+K RRLG RG S+Y Y G+R
Sbjct:  263 WLFENYEIGEGS-LPRCELYDHYKKHCAEHRMDPVNAASFGKLIRSVFHNLKTRRLGTRGNSKYHYYGIR 331

[Close]

BLAST of RFX-type winged-helix domain-containing protein vs. Ensembl Celegans
Match: daf-19 (RFX-like transcription factor daf-19 [Source:UniProtKB/Swiss-Prot;Acc:Q09555])

HSP 1 Score: 61.2326 bits (147), Expect = 1.316e-9
Identity = 26/70 (37.14%), Postives = 44/70 (62.86%), Query Frame = 3

Query:  534 WVLSHLEENKTTCLQKQEVYEDYKSYCMTYNIKCLSTADFGKVMKKNFPNIKARRLGARGQSRYCYSGLR 743
            W+  + E  + + L + E+Y+ YK +C  + +  ++ A FGK+++  F N+K RRLG RG S+Y Y G+R
Sbjct:  238 WLFENYEIGEGS-LPRCELYDHYKKHCAEHRMDPVNAASFGKLIRSVFHNLKTRRLGTRGNSKYHYYGIR 306

[Close]

BLAST of RFX-type winged-helix domain-containing protein vs. Ensembl Celegans
Match: daf-19 (RFX-like transcription factor daf-19 [Source:UniProtKB/Swiss-Prot;Acc:Q09555])

HSP 1 Score: 60.8474 bits (146), Expect = 1.458e-9
Identity = 26/70 (37.14%), Postives = 44/70 (62.86%), Query Frame = 3

Query:  534 WVLSHLEENKTTCLQKQEVYEDYKSYCMTYNIKCLSTADFGKVMKKNFPNIKARRLGARGQSRYCYSGLR 743
            W+  + E  + + L + E+Y+ YK +C  + +  ++ A FGK+++  F N+K RRLG RG S+Y Y G+R
Sbjct:  119 WLFENYEIGEGS-LPRCELYDHYKKHCAEHRMDPVNAASFGKLIRSVFHNLKTRRLGTRGNSKYHYYGIR 187

[Close]

BLAST of RFX-type winged-helix domain-containing protein vs. Ensembl Celegans
Match: daf-19 (RFX-like transcription factor daf-19 [Source:UniProtKB/Swiss-Prot;Acc:Q09555])

HSP 1 Score: 60.8474 bits (146), Expect = 1.559e-9
Identity = 26/70 (37.14%), Postives = 44/70 (62.86%), Query Frame = 3

Query:  534 WVLSHLEENKTTCLQKQEVYEDYKSYCMTYNIKCLSTADFGKVMKKNFPNIKARRLGARGQSRYCYSGLR 743
            W+  + E  + + L + E+Y+ YK +C  + +  ++ A FGK+++  F N+K RRLG RG S+Y Y G+R
Sbjct:   96 WLFENYEIGEGS-LPRCELYDHYKKHCAEHRMDPVNAASFGKLIRSVFHNLKTRRLGTRGNSKYHYYGIR 164

[Close]

BLAST of RFX-type winged-helix domain-containing protein vs. Ensembl Celegans
Match: daf-19 (RFX-like transcription factor daf-19 [Source:UniProtKB/Swiss-Prot;Acc:Q09555])

HSP 1 Score: 60.4622 bits (145), Expect = 1.812e-9
Identity = 26/70 (37.14%), Postives = 44/70 (62.86%), Query Frame = 3

Query:  534 WVLSHLEENKTTCLQKQEVYEDYKSYCMTYNIKCLSTADFGKVMKKNFPNIKARRLGARGQSRYCYSGLR 743
            W+  + E  + + L + E+Y+ YK +C  + +  ++ A FGK+++  F N+K RRLG RG S+Y Y G+R
Sbjct:   80 WLFENYEIGEGS-LPRCELYDHYKKHCAEHRMDPVNAASFGKLIRSVFHNLKTRRLGTRGNSKYHYYGIR 148

[Close]

BLAST of RFX-type winged-helix domain-containing protein vs. Ensembl Fly
Match: CG9727 (gene:FBgn0037445 transcript:FBtr0330193)

HSP 1 Score: 112.849 bits (281), Expect = 9.215e-26
Identity = 58/158 (36.71%), Postives = 85/158 (53.80%), Query Frame = 3

Query:  309 VDALEKTLTEDKSTKVKEIISQILNLSDTEKLLIQLQFPMTESDNGTFDSSMNIGFNNVDILGNSTIVEQEEASKWVLSHLEENKTTCLQKQEVYEDYKSYCMTYNIKCLSTADFGKVMKKNFPNIKARRLGARGQSRYCYSGLRNRQETQSPALKDI 782
            +  +E +L ++   ++ +I+ ++  L   EKL + L+ P   +D        N      +I  N TI        WV SHLE +    + KQ+VY DY +YC   +IK LSTADFGKVMK+ FP ++ RRLG RG SRYCY+ +R   +   P L  +
Sbjct:  247 LQVIETSLDDNAKLQISQILERVSGLKPIEKLFLYLRLPGECADTDPLRQPQNPLGTRSEI--NHTI-------NWVRSHLEHDAQVSIPKQDVYNDYIAYCERLSIKPLSTADFGKVMKQVFPGVRPRRLGTRGNSRYCYAAMRKTTKLTPPQLPQL 395

[Close]

BLAST of RFX-type winged-helix domain-containing protein vs. Ensembl Fly
Match: CG9727 (gene:FBgn0037445 transcript:FBtr0081730)

HSP 1 Score: 112.849 bits (281), Expect = 9.215e-26
Identity = 58/158 (36.71%), Postives = 85/158 (53.80%), Query Frame = 3

Query:  309 VDALEKTLTEDKSTKVKEIISQILNLSDTEKLLIQLQFPMTESDNGTFDSSMNIGFNNVDILGNSTIVEQEEASKWVLSHLEENKTTCLQKQEVYEDYKSYCMTYNIKCLSTADFGKVMKKNFPNIKARRLGARGQSRYCYSGLRNRQETQSPALKDI 782
            +  +E +L ++   ++ +I+ ++  L   EKL + L+ P   +D        N      +I  N TI        WV SHLE +    + KQ+VY DY +YC   +IK LSTADFGKVMK+ FP ++ RRLG RG SRYCY+ +R   +   P L  +
Sbjct:  247 LQVIETSLDDNAKLQISQILERVSGLKPIEKLFLYLRLPGECADTDPLRQPQNPLGTRSEI--NHTI-------NWVRSHLEHDAQVSIPKQDVYNDYIAYCERLSIKPLSTADFGKVMKQVFPGVRPRRLGTRGNSRYCYAAMRKTTKLTPPQLPQL 395

[Close]

BLAST of RFX-type winged-helix domain-containing protein vs. Ensembl Fly
Match: CG9727 (gene:FBgn0037445 transcript:FBtr0330192)

HSP 1 Score: 112.849 bits (281), Expect = 9.879e-26
Identity = 58/158 (36.71%), Postives = 85/158 (53.80%), Query Frame = 3

Query:  309 VDALEKTLTEDKSTKVKEIISQILNLSDTEKLLIQLQFPMTESDNGTFDSSMNIGFNNVDILGNSTIVEQEEASKWVLSHLEENKTTCLQKQEVYEDYKSYCMTYNIKCLSTADFGKVMKKNFPNIKARRLGARGQSRYCYSGLRNRQETQSPALKDI 782
            +  +E +L ++   ++ +I+ ++  L   EKL + L+ P   +D        N      +I  N TI        WV SHLE +    + KQ+VY DY +YC   +IK LSTADFGKVMK+ FP ++ RRLG RG SRYCY+ +R   +   P L  +
Sbjct:  247 LQVIETSLDDNAKLQISQILERVSGLKPIEKLFLYLRLPGECADTDPLRQPQNPLGTRSEI--NHTI-------NWVRSHLEHDAQVSIPKQDVYNDYIAYCERLSIKPLSTADFGKVMKQVFPGVRPRRLGTRGNSRYCYAAMRKTTKLTPPQLPQL 395

[Close]

BLAST of RFX-type winged-helix domain-containing protein vs. Ensembl Fly
Match: Rfx (gene:FBgn0020379 transcript:FBtr0337107)

HSP 1 Score: 57.7658 bits (138), Expect = 2.343e-8
Identity = 29/98 (29.59%), Postives = 51/98 (52.04%), Query Frame = 3

Query:  531 KWVLSHLEENKTTCLQKQEVYEDYKSYCMTYNIKCLSTADFGKVMKKNFPNIKARRLGARGQSRYCYSGLRNRQET--QSPALKDIGMVLEGNDTADD 818
            KW+  + E      L +  +Y  Y  +C  + ++ ++ A FGK+++  F  ++ RRLG RG S+Y Y G+R +  +   S A+ D  M+  G   + D
Sbjct:  373 KWLSRNYETADGVSLPRSTLYNHYMQHCSEHKLEPVNAASFGKLIRSVFSGLRTRRLGTRGNSKYHYYGIRIKPGSLLNSQAMDDKQMLAAGYGPSSD 470

[Close]

BLAST of RFX-type winged-helix domain-containing protein vs. Ensembl Fly
Match: Rfx (gene:FBgn0020379 transcript:FBtr0337105)

HSP 1 Score: 57.7658 bits (138), Expect = 2.361e-8
Identity = 29/98 (29.59%), Postives = 51/98 (52.04%), Query Frame = 3

Query:  531 KWVLSHLEENKTTCLQKQEVYEDYKSYCMTYNIKCLSTADFGKVMKKNFPNIKARRLGARGQSRYCYSGLRNRQET--QSPALKDIGMVLEGNDTADD 818
            KW+  + E      L +  +Y  Y  +C  + ++ ++ A FGK+++  F  ++ RRLG RG S+Y Y G+R +  +   S A+ D  M+  G   + D
Sbjct:  395 KWLSRNYETADGVSLPRSTLYNHYMQHCSEHKLEPVNAASFGKLIRSVFSGLRTRRLGTRGNSKYHYYGIRIKPGSLLNSQAMDDKQMLAAGYGPSSD 492

[Close]

BLAST of RFX-type winged-helix domain-containing protein vs. Ensembl Zebrafish
Match: rfx7a (regulatory factor X7a [Source:ZFIN;Acc:ZDB-GENE-100309-3])

HSP 1 Score: 124.02 bits (310), Expect = 2.801e-29
Identity = 66/180 (36.67%), Postives = 103/180 (57.22%), Query Frame = 3

Query:  318 LEKTLTEDKSTKVKEIISQILNLSDTEKLLIQLQFPMTESDNGTFDSSMNIGFNNVDILGNSTIVEQEEASKWVLSHLEENKTTCLQKQEVYEDYKSYCMTYNIKCLSTADFGKVMKKNFPNIKARRLGARGQSRYCYSGLRNRQETQSPALKDIGMVLEGNDTADDYRKRDNVANSEVE 857
            ++ ++ +   +KV  I+  +  L+D EKL + L+ P   S     +   ++          S+  +Q  A  W+ +HLEE+  T L KQEVY++YKSYC +     LS ADFGK+MK  FPN+KARRLG RG+S+YCYSGLR +   Q P+L ++ +   G D  + +     ++++E E
Sbjct:   34 IKNSICKTVQSKVDCILQDVEKLTDIEKLYLYLKLPSGPSSGNEKNEQSSM---------TSSRTQQMHAFSWIRNHLEEHPETSLPKQEVYDEYKSYCDSLGYHALSAADFGKIMKNVFPNMKARRLGMRGKSKYCYSGLRKKTFVQMPSLPNLDLHKSG-DGCEVFESTGQLSSAEDE 203

[Close]

BLAST of RFX-type winged-helix domain-containing protein vs. Ensembl Zebrafish
Match: rfx7b (regulatory factor X7b [Source:ZFIN;Acc:ZDB-GENE-170623-1])

HSP 1 Score: 118.627 bits (296), Expect = 2.012e-27
Identity = 64/161 (39.75%), Postives = 95/161 (59.01%), Query Frame = 3

Query:  348 TKVKEIISQILNLSDTEKLLIQLQFP---------MTESDNGTFDSSMNIGFNNVDILGNSTIVEQEEASKWVLSHLEENKTTCLQKQEVYEDYKSYCMTYNIKCLSTADFGKVMKKNFPNIKARRLGARGQSRYCYSGLRNRQETQSPALKDIGMVLEGN 803
            +KV+ I+  +   +D EKL + L+ P          TE+  G+   ++    N++    +S+  +Q  A  W+ +HLEE+  T L KQEVY++YKSYC       LS ADFGK+MK  FPN+KARRLG RG+S+YCYSGLR +     P+L ++ +   G+
Sbjct:   39 SKVESILQDVEKFTDIEKLYLYLKLPSGPSGGNDKRTENQRGSASPAL-CDQNSM----SSSRTQQMYAFNWIRNHLEEHPETSLPKQEVYDEYKSYCDNLGYHPLSAADFGKIMKNVFPNMKARRLGMRGKSKYCYSGLRKKAFVHMPSLPNLDLHKSGD 194

[Close]

BLAST of RFX-type winged-helix domain-containing protein vs. Ensembl Zebrafish
Match: rfx5 (regulatory factor X, 5 [Source:NCBI gene;Acc:101884332])

HSP 1 Score: 115.546 bits (288), Expect = 6.787e-27
Identity = 60/157 (38.22%), Postives = 88/157 (56.05%), Query Frame = 3

Query:  318 LEKTLTEDKSTKVKEIISQILNLSDTEKLLIQLQFPMTESDNGTFDSSMNIGFNNVDILGNSTIVEQEEASKWVLSHLEENKTTCLQKQEVYEDYKSYCMTYNIKCLSTADFGKVMKKNFPNIKARRLGARGQSRYCYSGLRNRQETQSPALKDIGM 788
            L+  ++++   KV +I+  +   SD +KL + LQ P   S       S ++  N  D         Q     W+ SHLEE+  TCL KQ+VYE Y+ +C     + LS A+FGK+++  FPNIKARRLG RGQS+YCYSG+R +     P L ++ +
Sbjct:   26 LKSNISKNVQGKVDKILEDVQRFSDNDKLYLYLQLPSGPSAGEKSGDSNSV--NTAD---------QLHTCNWIRSHLEEHPDTCLPKQDVYETYRKHCDNLQHRPLSAANFGKIIRDIFPNIKARRLGGRGQSKYCYSGIRRKTVLNMPLLPNLDL 171

[Close]

BLAST of RFX-type winged-helix domain-containing protein vs. Ensembl Zebrafish
Match: rfx4 (regulatory factor X, 4 [Source:NCBI gene;Acc:403016])

HSP 1 Score: 64.3142 bits (155), Expect = 2.213e-10
Identity = 33/125 (26.40%), Postives = 64/125 (51.20%), Query Frame = 3

Query:  531 KWVLSHLEENKTTCLQKQEVYEDYKSYCMTYNIKCLSTADFGKVMKKNFPNIKARRLGARGQSRYCYSGLRNRQETQSPALKDIGMVLEGNDTADDYRKRDNVANSEVESYSSTSVLNNDLSNVP 905
            +W+  + E  +  C+ +  +Y  Y  +C   + + ++ A FGK++++ FP +  RRLG RGQS+Y Y G+  ++ +Q     D+    +G    ++  K++     +  +YS  S L   L + P
Sbjct:   63 QWLEENYEIAEGVCIPRSALYMHYLDFCEKLDSQPVNAASFGKIIRQQFPQLTTRRLGTRGQSKYHYYGIAVKESSQ---YYDVMYSKKGAAWVNETGKKE--VTKQTVAYSPRSKLGTLLPDFP 182

[Close]

Query:  531 KWVLSHLEENKTTCLQKQEVYEDYKSYCMTYNIKCLSTADFGKVMKKNFPNIKARRLGARGQSRYCYSGLRNRQETQSPALKDIGMVLEGNDTADDYRKRDNVANSEVESYSSTSVLNNDLSNVP 905
            +W+  + E  +  C+ +  +Y  Y  +C   + + ++ A FGK++++ FP +  RRLG RGQS+Y Y G+  ++ +Q     D+    +G    ++  K++     +  +YS  S L   L + P
Sbjct:   63 QWLEENYEIAEGVCIPRSALYMHYLDFCEKLDSQPVNAASFGKIIRQQFPQLTTRRLGTRGQSKYHYYGIAVKESSQ---YYDVMYSKKGAAWVNETGKKE--VTKQTVAYSPRSKLGTLLPDFP 182

[Close]

BLAST of RFX-type winged-helix domain-containing protein vs. Ensembl Xenopus
Match: rfx7 (regulatory factor X7 [Source:NCBI gene;Acc:100038260])

HSP 1 Score: 111.309 bits (277), Expect = 5.539e-25
Identity = 56/127 (44.09%), Postives = 75/127 (59.06%), Query Frame = 3

Query:  501 STIVEQEEASKWVLSHLEENKTTCLQKQEVYEDYKSYCMTYNIKCLSTADFGKVMKKNFPNIKARRLGARGQSRYCYSGLRNRQETQSPALKDIGMVLEGNDTADDYRKRDNVANSEVESYSSTSVL 881
            S+  +Q  A  W+ + LEE+  T L KQEVY++YKSYC       LS ADFGK+MK  FPN+KARRLG RG+S+YCYSGLR +     P+L ++     G D  D       + N++ E  S+   L
Sbjct:  100 SSRAQQTHAFSWIRNTLEEHPETSLPKQEVYDEYKSYCDNLGYHPLSAADFGKIMKNVFPNMKARRLGTRGKSKYCYSGLRKKAFVHMPSLPNLDFNKSG-DGVDGIEVSTQLQNADEEVVSAACRL 225

[Close]

BLAST of RFX-type winged-helix domain-containing protein vs. Ensembl Xenopus
Match: rfx7 (regulatory factor X7 [Source:NCBI gene;Acc:100038260])

HSP 1 Score: 98.2117 bits (243), Expect = 9.123e-21
Identity = 53/129 (41.09%), Postives = 73/129 (56.59%), Query Frame = 3

Query:  501 STIVEQEEASKWVLSHLEENKTTCLQKQEVYEDYKSYCMTYNIKCLSTADFGKVMKKNFPNIKARRLGARGQSRYCY--SGLRNRQETQSPALKDIGMVLEGNDTADDYRKRDNVANSEVESYSSTSVL 881
            S+  +Q  A  W+ + LEE+  T L KQEVY++YKSYC       LS ADFGK+MK  FPN+KARRLG RG+S+Y +   GLR +     P+L ++     G D  D       + N++ E  S+   L
Sbjct:  101 SSRAQQTHAFSWIRNTLEEHPETSLPKQEVYDEYKSYCDNLGYHPLSAADFGKIMKNVFPNMKARRLGTRGKSKYPFLEVGLRKKAFVHMPSLPNLDFNKSG-DGVDGIEVSTQLQNADEEVVSAACRL 228

[Close]

BLAST of RFX-type winged-helix domain-containing protein vs. Ensembl Xenopus
Match: rfx2 (regulatory factor X2 [Source:NCBI gene;Acc:100144734])

HSP 1 Score: 58.9214 bits (141), Expect = 1.463e-8
Identity = 23/71 (32.39%), Postives = 41/71 (57.75%), Query Frame = 3

Query:  531 KWVLSHLEENKTTCLQKQEVYEDYKSYCMTYNIKCLSTADFGKVMKKNFPNIKARRLGARGQSRYCYSGLR 743
            +W+L + E  +   L +  +Y  Y  +C  + +  ++ A FGK+++  F  ++ RRLG RG S+Y Y G+R
Sbjct:  206 QWLLDNYETAEGVSLPRSSLYNHYLRHCQDHKLDPVNAASFGKLIRSVFMGLRTRRLGTRGNSKYHYYGIR 276

[Close]

BLAST of RFX-type winged-helix domain-containing protein vs. Ensembl Xenopus
Match: rfx2 (regulatory factor X2 [Source:NCBI gene;Acc:100144734])

HSP 1 Score: 58.9214 bits (141), Expect = 1.498e-8
Identity = 23/71 (32.39%), Postives = 41/71 (57.75%), Query Frame = 3

Query:  531 KWVLSHLEENKTTCLQKQEVYEDYKSYCMTYNIKCLSTADFGKVMKKNFPNIKARRLGARGQSRYCYSGLR 743
            +W+L + E  +   L +  +Y  Y  +C  + +  ++ A FGK+++  F  ++ RRLG RG S+Y Y G+R
Sbjct:  176 QWLLDNYETAEGVSLPRSSLYNHYLRHCQDHKLDPVNAASFGKLIRSVFMGLRTRRLGTRGNSKYHYYGIR 246

[Close]

BLAST of RFX-type winged-helix domain-containing protein vs. Ensembl Xenopus
Match: rfx2 (regulatory factor X2 [Source:NCBI gene;Acc:100144734])

HSP 1 Score: 58.9214 bits (141), Expect = 1.597e-8
Identity = 23/71 (32.39%), Postives = 41/71 (57.75%), Query Frame = 3

Query:  531 KWVLSHLEENKTTCLQKQEVYEDYKSYCMTYNIKCLSTADFGKVMKKNFPNIKARRLGARGQSRYCYSGLR 743
            +W+L + E  +   L +  +Y  Y  +C  + +  ++ A FGK+++  F  ++ RRLG RG S+Y Y G+R
Sbjct:  181 QWLLDNYETAEGVSLPRSSLYNHYLRHCQDHKLDPVNAASFGKLIRSVFMGLRTRRLGTRGNSKYHYYGIR 251

[Close]

BLAST of RFX-type winged-helix domain-containing protein vs. Ensembl Mouse
Match: Rfx5 (regulatory factor X, 5 (influences HLA class II expression) [Source:MGI Symbol;Acc:MGI:1858421])

HSP 1 Score: 120.939 bits (302), Expect = 3.427e-30
Identity = 76/252 (30.16%), Postives = 130/252 (51.59%), Query Frame = 3

Query:  318 LEKTLTEDKSTKVKEIISQILNLSDTEKLLIQLQFPMTESDNGTFDSSMNIGFNNVDILGNSTIVEQEE---ASKWVLSHLEENKTTCLQKQEVYEDYKSYCMTYNI-KCLSTADFGKVMKKNFPNIKARRLGARGQSRYCYSGLRNRQETQSPALKDIGMVLEGNDTADDYRKRDNVANSEVESYSSTSVLNNDLSNVPEYELSPNILIDSALVIIEFIKQVAMNKNIMSLKQAVKHLLSNSQVDMRSPHA 1061
            L  T+++    KV+ I+ ++   SD +KL + LQ P          S  ++G  + +     +++  EE   A +W+ +HLEE+  TCL KQ VY+ Y+ YC +    + LSTA+FGK++++ FP+IKARRLG RGQS+YCYSG+R +     P L   G+ L+G+++ +                     +  ++S  P  E     L+++A  +     +  + ++  S+ Q  ++LL    +  RS HA
Sbjct:   33 LRGTISKAVQNKVEGILQEVQKFSDNDKLYLYLQLP----------SGPSVGEKSSE----PSLLSNEEYMYAYRWIRNHLEEHMDTCLPKQSVYDAYRKYCESLACCRPLSTANFGKIIREIFPDIKARRLGGRGQSKYCYSGIRRKTLVSMPPLP--GLDLKGSESPE---------------------MGPEVSPAPRDE-----LVEAACALTCDWAERILKRSFSSIVQVARYLLQQHLISARSAHA 242

[Close]

Query:  318 LEKTLTEDKSTKVKEIISQILNLSDTEKLLIQLQFPMTESDNGTFDSSMNIGFNNVDILGNSTIVEQEE---ASKWVLSHLEENKTTCLQKQEVYEDYKSYCMTYNI-KCLSTADFGKVMKKNFPNIKARRLGARGQSRYCYSGLRNRQETQSPALKDIGMVLEGNDTADDYRKRDNVANSEVESYSSTSVLNNDLSNVPEYELSPNILIDSALVIIEFIKQVAMNKNIMSLKQAVKHLLSNSQVDMRSPHA 1061
            L  T+++    KV+ I+ ++   SD +KL + LQ P          S  ++G  + +     +++  EE   A +W+ +HLEE+  TCL KQ VY+ Y+ YC +    + LSTA+FGK++++ FP+IKARRLG RGQS+YCYSG+R +     P L   G+ L+G+++ +                     +  ++S  P  E     L+++A  +     +  + ++  S+ Q  ++LL    +  RS HA
Sbjct:   33 LRGTISKAVQNKVEGILQEVQKFSDNDKLYLYLQLP----------SGPSVGEKSSE----PSLLSNEEYMYAYRWIRNHLEEHMDTCLPKQSVYDAYRKYCESLACCRPLSTANFGKIIREIFPDIKARRLGGRGQSKYCYSGIRRKTLVSMPPLP--GLDLKGSESPE---------------------MGPEVSPAPRDE-----LVEAACALTCDWAERILKRSFSSIVQVARYLLQQHLISARSAHA 242

[Close]

BLAST of RFX-type winged-helix domain-containing protein vs. Ensembl Mouse
Match: Rfx5 (regulatory factor X, 5 (influences HLA class II expression) [Source:MGI Symbol;Acc:MGI:1858421])

HSP 1 Score: 122.479 bits (306), Expect = 5.436e-29
Identity = 76/252 (30.16%), Postives = 130/252 (51.59%), Query Frame = 3

Query:  318 LEKTLTEDKSTKVKEIISQILNLSDTEKLLIQLQFPMTESDNGTFDSSMNIGFNNVDILGNSTIVEQEE---ASKWVLSHLEENKTTCLQKQEVYEDYKSYCMTYNI-KCLSTADFGKVMKKNFPNIKARRLGARGQSRYCYSGLRNRQETQSPALKDIGMVLEGNDTADDYRKRDNVANSEVESYSSTSVLNNDLSNVPEYELSPNILIDSALVIIEFIKQVAMNKNIMSLKQAVKHLLSNSQVDMRSPHA 1061
            L  T+++    KV+ I+ ++   SD +KL + LQ P          S  ++G  + +     +++  EE   A +W+ +HLEE+  TCL KQ VY+ Y+ YC +    + LSTA+FGK++++ FP+IKARRLG RGQS+YCYSG+R +     P L   G+ L+G+++ +                     +  ++S  P  E     L+++A  +     +  + ++  S+ Q  ++LL    +  RS HA
Sbjct:   33 LRGTISKAVQNKVEGILQEVQKFSDNDKLYLYLQLP----------SGPSVGEKSSE----PSLLSNEEYMYAYRWIRNHLEEHMDTCLPKQSVYDAYRKYCESLACCRPLSTANFGKIIREIFPDIKARRLGGRGQSKYCYSGIRRKTLVSMPPLP--GLDLKGSESPE---------------------MGPEVSPAPRDE-----LVEAACALTCDWAERILKRSFSSIVQVARYLLQQHLISARSAHA 242

[Close]

BLAST of RFX-type winged-helix domain-containing protein vs. Ensembl Mouse
Match: Rfx5 (regulatory factor X, 5 (influences HLA class II expression) [Source:MGI Symbol;Acc:MGI:1858421])

HSP 1 Score: 122.479 bits (306), Expect = 5.436e-29
Identity = 76/252 (30.16%), Postives = 130/252 (51.59%), Query Frame = 3

Query:  318 LEKTLTEDKSTKVKEIISQILNLSDTEKLLIQLQFPMTESDNGTFDSSMNIGFNNVDILGNSTIVEQEE---ASKWVLSHLEENKTTCLQKQEVYEDYKSYCMTYNI-KCLSTADFGKVMKKNFPNIKARRLGARGQSRYCYSGLRNRQETQSPALKDIGMVLEGNDTADDYRKRDNVANSEVESYSSTSVLNNDLSNVPEYELSPNILIDSALVIIEFIKQVAMNKNIMSLKQAVKHLLSNSQVDMRSPHA 1061
            L  T+++    KV+ I+ ++   SD +KL + LQ P          S  ++G  + +     +++  EE   A +W+ +HLEE+  TCL KQ VY+ Y+ YC +    + LSTA+FGK++++ FP+IKARRLG RGQS+YCYSG+R +     P L   G+ L+G+++ +                     +  ++S  P  E     L+++A  +     +  + ++  S+ Q  ++LL    +  RS HA
Sbjct:   33 LRGTISKAVQNKVEGILQEVQKFSDNDKLYLYLQLP----------SGPSVGEKSSE----PSLLSNEEYMYAYRWIRNHLEEHMDTCLPKQSVYDAYRKYCESLACCRPLSTANFGKIIREIFPDIKARRLGGRGQSKYCYSGIRRKTLVSMPPLP--GLDLKGSESPE---------------------MGPEVSPAPRDE-----LVEAACALTCDWAERILKRSFSSIVQVARYLLQQHLISARSAHA 242

[Close]

BLAST of RFX-type winged-helix domain-containing protein vs. Ensembl Mouse
Match: Rfx5 (regulatory factor X, 5 (influences HLA class II expression) [Source:MGI Symbol;Acc:MGI:1858421])

HSP 1 Score: 122.479 bits (306), Expect = 5.436e-29
Identity = 76/252 (30.16%), Postives = 130/252 (51.59%), Query Frame = 3

Query:  318 LEKTLTEDKSTKVKEIISQILNLSDTEKLLIQLQFPMTESDNGTFDSSMNIGFNNVDILGNSTIVEQEE---ASKWVLSHLEENKTTCLQKQEVYEDYKSYCMTYNI-KCLSTADFGKVMKKNFPNIKARRLGARGQSRYCYSGLRNRQETQSPALKDIGMVLEGNDTADDYRKRDNVANSEVESYSSTSVLNNDLSNVPEYELSPNILIDSALVIIEFIKQVAMNKNIMSLKQAVKHLLSNSQVDMRSPHA 1061
            L  T+++    KV+ I+ ++   SD +KL + LQ P          S  ++G  + +     +++  EE   A +W+ +HLEE+  TCL KQ VY+ Y+ YC +    + LSTA+FGK++++ FP+IKARRLG RGQS+YCYSG+R +     P L   G+ L+G+++ +                     +  ++S  P  E     L+++A  +     +  + ++  S+ Q  ++LL    +  RS HA
Sbjct:   33 LRGTISKAVQNKVEGILQEVQKFSDNDKLYLYLQLP----------SGPSVGEKSSE----PSLLSNEEYMYAYRWIRNHLEEHMDTCLPKQSVYDAYRKYCESLACCRPLSTANFGKIIREIFPDIKARRLGGRGQSKYCYSGIRRKTLVSMPPLP--GLDLKGSESPE---------------------MGPEVSPAPRDE-----LVEAACALTCDWAERILKRSFSSIVQVARYLLQQHLISARSAHA 242

[Close]

BLAST of RFX-type winged-helix domain-containing protein vs. UniProt/SwissProt
Match: sp|Q9JL61|RFX5_MOUSE (DNA-binding protein Rfx5 OS=Mus musculus OX=10090 GN=Rfx5 PE=1 SV=2)

HSP 1 Score: 122.479 bits (306), Expect = 3.802e-28
Identity = 76/252 (30.16%), Postives = 130/252 (51.59%), Query Frame = 3

Query:  318 LEKTLTEDKSTKVKEIISQILNLSDTEKLLIQLQFPMTESDNGTFDSSMNIGFNNVDILGNSTIVEQEE---ASKWVLSHLEENKTTCLQKQEVYEDYKSYCMTYNI-KCLSTADFGKVMKKNFPNIKARRLGARGQSRYCYSGLRNRQETQSPALKDIGMVLEGNDTADDYRKRDNVANSEVESYSSTSVLNNDLSNVPEYELSPNILIDSALVIIEFIKQVAMNKNIMSLKQAVKHLLSNSQVDMRSPHA 1061
            L  T+++    KV+ I+ ++   SD +KL + LQ P          S  ++G  + +     +++  EE   A +W+ +HLEE+  TCL KQ VY+ Y+ YC +    + LSTA+FGK++++ FP+IKARRLG RGQS+YCYSG+R +     P L   G+ L+G+++ +                     +  ++S  P  E     L+++A  +     +  + ++  S+ Q  ++LL    +  RS HA
Sbjct:   33 LRGTISKAVQNKVEGILQEVQKFSDNDKLYLYLQLP----------SGPSVGEKSSE----PSLLSNEEYMYAYRWIRNHLEEHMDTCLPKQSVYDAYRKYCESLACCRPLSTANFGKIIREIFPDIKARRLGGRGQSKYCYSGIRRKTLVSMPPLP--GLDLKGSESPE---------------------MGPEVSPAPRDE-----LVEAACALTCDWAERILKRSFSSIVQVARYLLQQHLISARSAHA 242

[Close]

BLAST of RFX-type winged-helix domain-containing protein vs. UniProt/SwissProt
Match: sp|P48382|RFX5_HUMAN (DNA-binding protein RFX5 OS=Homo sapiens OX=9606 GN=RFX5 PE=1 SV=1)

HSP 1 Score: 117.857 bits (294), Expect = 1.093e-26
Identity = 77/251 (30.68%), Postives = 126/251 (50.20%), Query Frame = 3

Query:  318 LEKTLTEDKSTKVKEIISQILNLSDTEKLLIQLQFPMTESDNGTFDSSMNIGFNNVDILGNSTIVEQEE--ASKWVLSHLEENKTTCLQKQEVYEDYKSYCMTYNI-KCLSTADFGKVMKKNFPNIKARRLGARGQSRYCYSGLRNRQETQSPALKDIGMVLEGNDTADDYRKRDNVANSEVESYSSTSVLNNDLSNVPEYELSPNILIDSALVIIEFIKQVAMNKNIMSLKQAVKHLLSNSQVDMRSPHA 1061
            L  T+++    KV+ I+  +   SD +KL + LQ P   S   T D S             ST+  +E   A +W+ +HLEE+  TCL KQ VY+ Y+ YC +    + LSTA+FGK++++ FP+IKARRLG RGQS+YCYSG+R +     P L   G+ L+G+++ +                     +  +++  P  E     L+++A  +     +  + ++  S+ +  + LL    +  RS HA
Sbjct:   34 LRGTISKAVQNKVEGILQDVQKFSDNDKLYLYLQLP---SGPTTGDKSSE----------PSTLSNEEYMYAYRWIRNHLEEHTDTCLPKQSVYDAYRKYCESLACCRPLSTANFGKIIREIFPDIKARRLGGRGQSKYCYSGIRRKTLVSMPPLP--GLDLKGSESPE---------------------MGPEVTPAPRDE-----LVEAACALTCDWAERILKRSFSSIVEVARFLLQQHLISARSAHA 243

[Close]

BLAST of RFX-type winged-helix domain-containing protein vs. UniProt/SwissProt
Match: sp|Q2KHR2|RFX7_HUMAN (DNA-binding protein RFX7 OS=Homo sapiens OX=9606 GN=RFX7 PE=1 SV=1)

HSP 1 Score: 110.923 bits (276), Expect = 4.298e-24
Identity = 54/117 (46.15%), Postives = 72/117 (61.54%), Query Frame = 3

Query:  498 NSTIVEQEEASKWVLSHLEENKTTCLQKQEVYEDYKSYCMTYNIKCLSTADFGKVMKKNFPNIKARRLGARGQSRYCYSGLRNRQETQSPALKDI-----GMVLEGNDTADDYRKRD 833
            +S+  +Q  A  W+ + LEE+  T L KQEVY++YKSYC       LS ADFGK+MK  FPN+KARRLG RG+S+YCYSGLR +     P L ++     G  LEG + +   +  D
Sbjct:    2 SSSRAQQMHAFSWIRNTLEEHPETSLPKQEVYDEYKSYCDNLGYHPLSAADFGKIMKNVFPNMKARRLGTRGKSKYCYSGLRKKAFVHMPTLPNLDFHKTGDGLEGAEPSGQLQNID 118

[Close]

BLAST of RFX-type winged-helix domain-containing protein vs. UniProt/SwissProt
Match: sp|P48383|SAK1_SCHPO (Protein sak1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=sak1 PE=1 SV=2)

HSP 1 Score: 70.8626 bits (172), Expect = 1.573e-11
Identity = 32/85 (37.65%), Postives = 49/85 (57.65%), Query Frame = 3

Query:  495 GNSTIVEQEEASKWVLSHLEENKTTCLQKQEVYEDYKSYCMTYNIKCLSTADFGKVMKKNFPNIKARRLGARGQSRYCYSGLRNR 749
             NS    Q     W+    EE +   +Q+ ++Y  Y   C + +IK L++A FGK+++  FP+IK RRLG RG S+Y Y G++ R
Sbjct:   91 ANSEKFRQVFGICWLKRACEEQQDAAVQRNQIYAHYVEICNSLHIKPLNSASFGKLVRLLFPSIKTRRLGMRGHSKYHYCGIKLR 175

[Close]

BLAST of RFX-type winged-helix domain-containing protein vs. UniProt/SwissProt
Match: sp|Q7TNK1|RFX4_MOUSE (Transcription factor RFX4 OS=Mus musculus OX=10090 GN=Rfx4 PE=1 SV=1)

HSP 1 Score: 65.0846 bits (157), Expect = 1.028e-9
Identity = 34/125 (27.20%), Postives = 63/125 (50.40%), Query Frame = 3

Query:  531 KWVLSHLEENKTTCLQKQEVYEDYKSYCMTYNIKCLSTADFGKVMKKNFPNIKARRLGARGQSRYCYSGLRNRQETQSPALKDIGMVLEGNDTADDYRKRDNVANSEVESYSSTSVLNNDLSNVP 905
            +W+  + E  +  C+ +  +Y  Y  +C   + + ++ A FGK++++ FP +  RRLG RGQS+Y Y G+  ++ +Q     D+    +G     +  KR+     +  +YS  S L   L + P
Sbjct:   63 QWLEENYEIAEGVCIPRSALYMHYLDFCEKNDTQPVNAASFGKIIRQQFPQLTTRRLGTRGQSKYHYYGIAVKESSQ---YYDVMYSKKGAAWVSETGKRE--VTKQTVAYSPRSKLGTLLPDFP 182

[Close]

BLAST of RFX-type winged-helix domain-containing protein vs. TrEMBL
Match: A0A158R985 (RFX-type winged-helix domain-containing protein OS=Taenia asiatica OX=60517 GN=TASK_LOCUS6820 PE=4 SV=1)

HSP 1 Score: 176.407 bits (446), Expect = 2.254e-43
Identity = 98/285 (34.39%), Postives = 154/285 (54.04%), Query Frame = 3

Query:  309 VDALEKTLTEDKSTKVKEIISQILNLSDTEKLLIQLQFPMTESDNGTFDSSM---NIGFNN-------VDILGNSTI---------VEQEEASKWVLSHLEENKTTCLQKQEVYEDYKSYCMTYNIKCLSTADFGKVMKKNFPNIKARRLGARGQSRYCYSGLRNRQETQSPALKDIGMVLEGNDTADDYR----------KRDNVANSEVESYSSTSVLNNDLSNVPEYELSPNILIDSALVIIEFIKQVAMNKNIMSLKQAVKHLLSNSQVDMRSPHALRLCS 1076
            +++LEK +T +  +++  ++ +  +  DTEK+L  L  P+    +G   S++   +IG N        V I G S           VEQ +A  W++SHLEE+ +TCL+K EVYEDY++YC  +N K L+TADFGKVMK+ FPN++ RRLG RGQSRYCY G+R + E Q+P+L D+ + L      +++R          ++ +    EV     T  +   L       ++  IL+D   +I+E+ + V +     SL    +HL+S+  V   S HA  L +
Sbjct:   17 LNSLEKAVTPEARSRIDALVREFASFRDTEKILCALLLPV--EPHGNCASALIEDDIGPNGFEVNSLGVGIFGGSGCSSSLHLSNQVEQSQAYTWIMSHLEEDSSTCLRKDEVYEDYRAYCEKHNQKTLNTADFGKVMKRAFPNVRPRRLGQRGQSRYCYGGMRKKLEVQAPSLPDLTLELSVPPATNNFRSGSSSVSSIDEQRHSQRGEVSPTWPTEEVRTVLG------VTGPILVDVVRIILEYARTV-LGTEFASLLHFAQHLVSDRYVTAHSRHAFALIA 292

[Close]

BLAST of RFX-type winged-helix domain-containing protein vs. TrEMBL
Match: A0A0R3WI66 (RFX-type winged-helix domain-containing protein OS=Hydatigena taeniaeformis OX=6205 GN=TTAC_LOCUS275 PE=4 SV=1)

HSP 1 Score: 176.022 bits (445), Expect = 2.532e-43
Identity = 97/284 (34.15%), Postives = 148/284 (52.11%), Query Frame = 3

Query:  309 VDALEKTLTEDKSTKVKEIISQILNLSDTEKLLIQLQFPMTESDNGTF----DSSMNIGFN----NVDILGNSTI---------VEQEEASKWVLSHLEENKTTCLQKQEVYEDYKSYCMTYNIKCLSTADFGKVMKKNFPNIKARRLGARGQSRYCYSGLRNRQETQSPALKDIGMVLEGNDTADDYRK---------RDNVANSEVESYSSTSVLNNDLSNVPEYELSPNILIDSALVIIEFIKQVAMNKNIMSLKQAVKHLLSNSQVDMRSPHALRLCSIF 1082
            +++LEKT++ +  ++++ ++ +  +  DTEK+L  L  P     +G      D     GF      V I G S           VEQ +A  W++SHLEE+ +TCL+K EVYEDY++YC  +N K L+TADFGKVMK+ FPN++ RRLG RGQSRYCY G+R + E Q+P+L D+ + L       ++R             ++  EV     T  +   L       ++  IL D   +I+E+ + V +     SL    + L+S+  V   S HA  L + F
Sbjct:   17 LNSLEKTVSPEARSRIEALVREFSSFKDTEKILCALLLPAEPHGSGVPALVEDDIGPNGFEVNSLGVGIFGGSGCSSSLHLSNQVEQSQAYTWIMSHLEEDSSTCLRKDEVYEDYRAYCEKHNQKTLNTADFGKVMKRAFPNVRPRRLGQRGQSRYCYGGMRKKLEVQAPSLPDLTLELSAPSATSNFRSGSSSVSSTDEQRLSQHEVSPAWPTEEVRTVLG------VTGPILADVVRIILEYARTV-LGTEFTSLLHFAQRLVSDRYVTAHSRHAFALIAHF 293

[Close]

BLAST of RFX-type winged-helix domain-containing protein vs. TrEMBL
Match: A0A5K3ERA4 (Uncharacterized protein OS=Mesocestoides corti OX=53468 PE=4 SV=1)

HSP 1 Score: 171.785 bits (434), Expect = 2.712e-43
Identity = 99/272 (36.40%), Postives = 148/272 (54.41%), Query Frame = 3

Query:  318 LEKTLTEDKSTKVKEIISQILNLSDTEKLLIQLQFPMTESD-------------NGTFDSSMNIGF---NNVDILGNSTIVEQEEASKWVLSHLEENKTTCLQKQEVYEDYKSYCMTYNIKCLSTADFGKVMKKNFPNIKARRLGARGQSRYCYSGLRNRQETQSPALKDIGMVLEGNDTADDYRKRDNVANSEVESYSS-----TSVLNNDLSNVPEYELSPNILIDSALVIIEFIKQVAMNKNIMSLKQAVKHLLSNSQVDMRSPHALRL 1070
             EK +T D  +++  ++ +  +  DTEKLL  L  P   S              NG   +S+ +G    +    L  S  VEQ +A  W++SHLEE+ +TCL+K EVYEDY+ YC  +N K L+TADFGKVMK+ FPN+K RRLG RGQSRYCY G+R + E Q P+L D+   L     + ++R   +  +S  +  SS     +S  + ++  V    ++  +L D A V++E+ + V       SL +  +HL++N  V  RS H+  L
Sbjct:   20 FEKAVTPDSRSRIDALLREFSSFKDTEKLLFCLLLPTEPSGICSSSLADDEISANGFEINSLGVGLFSGSGCSSLHLSNQVEQSQAYTWIMSHLEEDASTCLRKDEVYEDYRLYCEKHNQKTLNTADFGKVMKRAFPNVKPRRLGQRGQSRYCYGGMRKKLEVQPPSLPDLTAELSAPTLSTNFRSASSSVSSTDDHRSSLRGEASSWFSEEVRGV--LGVTGPVLADVANVLLEYAQNV-FGTTFTSLTKLAEHLVANRYVSTRSRHSFAL 288

[Close]

BLAST of RFX-type winged-helix domain-containing protein vs. TrEMBL
Match: A0A0R3TU13 (RFX-type winged-helix domain-containing protein OS=Rodentolepis nana OX=102285 GN=HNAJ_LOCUS11216 PE=4 SV=1)

HSP 1 Score: 172.94 bits (437), Expect = 3.250e-43
Identity = 107/280 (38.21%), Postives = 156/280 (55.71%), Query Frame = 3

Query:  318 LEKTLTEDKSTKVKEIISQILNLSDTEKLLIQLQFPMTES---------DNGTFDSSMNIGFNNVDILGNSTIVEQEEASKWVLSHLEENKTTCLQKQEVYEDYKSYCMTYNIKCLSTADFGKVMKKNFPNIKARRLGARGQSRYCYSGLRNRQETQSPALKDIGMVLEGNDTADDYRKRDNVANSEVESYSSTSVLNNDLSNVPEYELSPNILIDSALVIIEFIKQVAMNKNIMSLKQAVKHLLSNSQVDMRSPHALRLCSIFHQVDGQKLYPINKYSA 1130
            L+ TL+ +   +V  +++  L+L++ EKL+  L+  MT+S         D+ +   S   G  +V     S  VEQ  A  W+ SHLEE+ TTCL+K EVYEDYK+YC    +K L+TADFGKVMK+ FPN++ RRLG RGQSRYCY G+R +++TQ+P L D+ + L  +  +D YR             S+TS+ + ++      E S   +ID+  ++ E+  Q  +     SL Q   HL+ N  V+  S HAL L S   Q   Q+L  IN  S+
Sbjct:   20 LQNTLSPESQARVDGVLNNFLSLNNDEKLVCLLKI-MTDSAVAGQSSLFDDDSGAESNTAGTFSVSTFQVSNQVEQGYAFTWIKSHLEEDSTTCLRKDEVYEDYKNYCEQQRMKPLNTADFGKVMKRAFPNVRPRRLGQRGQSRYCYGGMRKKRDTQAPLLPDLTLELSNSSNSDPYRSGPP---------STTSIDDQEVRAALGVEGS--TIIDAIRIVTEY-AQTVVGGEFSSLLQLALHLIRNRFVNGHSTHALSLISYNQQ---QQLKRINPTSS 283

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BLAST of RFX-type winged-helix domain-containing protein vs. TrEMBL
Match: A0A5K3EPU5 (Uncharacterized protein OS=Mesocestoides corti OX=53468 PE=4 SV=1)

HSP 1 Score: 175.252 bits (443), Expect = 5.364e-43
Identity = 99/272 (36.40%), Postives = 148/272 (54.41%), Query Frame = 3

Query:  318 LEKTLTEDKSTKVKEIISQILNLSDTEKLLIQLQFPMTESD-------------NGTFDSSMNIGF---NNVDILGNSTIVEQEEASKWVLSHLEENKTTCLQKQEVYEDYKSYCMTYNIKCLSTADFGKVMKKNFPNIKARRLGARGQSRYCYSGLRNRQETQSPALKDIGMVLEGNDTADDYRKRDNVANSEVESYSS-----TSVLNNDLSNVPEYELSPNILIDSALVIIEFIKQVAMNKNIMSLKQAVKHLLSNSQVDMRSPHALRL 1070
             EK +T D  +++  ++ +  +  DTEKLL  L  P   S              NG   +S+ +G    +    L  S  VEQ +A  W++SHLEE+ +TCL+K EVYEDY+ YC  +N K L+TADFGKVMK+ FPN+K RRLG RGQSRYCY G+R + E Q P+L D+   L     + ++R   +  +S  +  SS     +S  + ++  V    ++  +L D A V++E+ + V       SL +  +HL++N  V  RS H+  L
Sbjct:   20 FEKAVTPDSRSRIDALLREFSSFKDTEKLLFCLLLPTEPSGICSSSLADDEISANGFEINSLGVGLFSGSGCSSLHLSNQVEQSQAYTWIMSHLEEDASTCLRKDEVYEDYRLYCEKHNQKTLNTADFGKVMKRAFPNVKPRRLGQRGQSRYCYGGMRKKLEVQPPSLPDLTAELSAPTLSTNFRSASSSVSSTDDHRSSLRGEASSWFSEEVRGV--LGVTGPVLADVANVLLEYAQNV-FGTTFTSLTKLAEHLVANRYVSTRSRHSFAL 288

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BLAST of RFX-type winged-helix domain-containing protein vs. Ensembl Cavefish
Match: rfx7b (regulatory factor X7b [Source:ZFIN;Acc:ZDB-GENE-170623-1])

HSP 1 Score: 119.398 bits (298), Expect = 8.086e-28
Identity = 64/162 (39.51%), Postives = 94/162 (58.02%), Query Frame = 3

Query:  318 LEKTLTEDKSTKVKEIISQILNLSDTEKLLIQLQFPMTESDNGTFDSSMNIGFNNVDILGNSTIVEQEEASKWVLSHLEENKTTCLQKQEVYEDYKSYCMTYNIKCLSTADFGKVMKKNFPNIKARRLGARGQSRYCYSGLRNRQETQSPALKDIGMVLEGN 803
            ++ ++ +   +KV  I+  +   +D EKL + L+ P   S +G   S  N          +S+  +Q  A  W+ +HLEE+  T L KQEVY++YKSYC       LS ADFGK+MK  FPN+KARRLG RG+S+YCYSGLR +     P+L ++ +   G+
Sbjct:   42 IKNSICKSVQSKVDSILQDVEKFTDIEKLYLYLKLPSGPS-SGNDKSDQNST--------SSSRTQQMYAFNWIRNHLEEHPETSLPKQEVYDEYKSYCDNLGYHPLSAADFGKIMKNVFPNMKARRLGMRGKSKYCYSGLRKKAFVHMPSLPNLDLHKSGD 194

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BLAST of RFX-type winged-helix domain-containing protein vs. Ensembl Cavefish
Match: rfx7b (regulatory factor X7b [Source:ZFIN;Acc:ZDB-GENE-170623-1])

HSP 1 Score: 117.857 bits (294), Expect = 3.126e-27
Identity = 65/171 (38.01%), Postives = 97/171 (56.73%), Query Frame = 3

Query:  318 LEKTLTEDKSTKVKEIISQILNLSDTEKLLIQLQFP---------MTESDNGTFDSSMNIGFNNVDILGNSTIVEQEEASKWVLSHLEENKTTCLQKQEVYEDYKSYCMTYNIKCLSTADFGKVMKKNFPNIKARRLGARGQSRYCYSGLRNRQETQSPALKDIGMVLEGN 803
            ++ ++ +   +KV  I+  +   +D EKL + L+ P          TE+  G+  S      N+     +S+  +Q  A  W+ +HLEE+  T L KQEVY++YKSYC       LS ADFGK+MK  FPN+KARRLG RG+S+YCYSGLR +     P+L ++ +   G+
Sbjct:   42 IKNSICKSVQSKVDSILQDVEKFTDIEKLYLYLKLPSGPSSGNDKRTENQRGS-TSPATCDQNST----SSSRTQQMYAFNWIRNHLEEHPETSLPKQEVYDEYKSYCDNLGYHPLSAADFGKIMKNVFPNMKARRLGMRGKSKYCYSGLRKKAFVHMPSLPNLDLHKSGD 207

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BLAST of RFX-type winged-helix domain-containing protein vs. Ensembl Cavefish
Match: rfx7a (DNA-binding protein RFX7-like [Source:NCBI gene;Acc:103028958])

HSP 1 Score: 117.087 bits (292), Expect = 4.701e-27
Identity = 68/190 (35.79%), Postives = 103/190 (54.21%), Query Frame = 3

Query:  318 LEKTLTEDKSTKVKEIISQILNLSDTEKLLIQLQFPMTESDNG--TFDSSMNIGFNNVDILGNSTIVEQEEASKWVLSHLEENKTTCLQKQEVYEDYKSYCMTYNIKCLSTADFGKVMKKNFPNIKARRLGARGQSRYCYSGLRNRQETQSPALKDIGMVLEGNDTADDYRKRDNVANSEVESYSSTSVL 881
            ++ ++ +   +KV  I+  +   +D EKL + L+ P   S     T  S ++           S+  +Q  A  W+ +HLEE+  T L KQEVY++YKSYC       LS ADFGK+MK  FPN+KARRLG RG+S+YCYSGLR +     P+L  + +   G D  + +    + ++ E E  S++  L
Sbjct:   41 IKNSICKSVQSKVDGILQDVEKFTDIEKLYLYLRLPSGPSSCAEKTEQSCLS-----------SSRSQQMHAFGWIRNHLEEHPETSLPKQEVYDEYKSYCDNLGYHALSAADFGKIMKNVFPNMKARRLGMRGKSKYCYSGLRKKAFIHMPSLPSLELHKTG-DGCEVFEPIGHCSSGEDEVRSASCGL 218

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BLAST of RFX-type winged-helix domain-containing protein vs. Ensembl Cavefish
Match: rfx5 (regulatory factor X5 [Source:NCBI gene;Acc:103044951])

HSP 1 Score: 115.161 bits (287), Expect = 8.165e-27
Identity = 60/157 (38.22%), Postives = 86/157 (54.78%), Query Frame = 3

Query:  318 LEKTLTEDKSTKVKEIISQILNLSDTEKLLIQLQFPMTESDNGTFDSSMNIGFNNVDILGNSTIVEQEEASKWVLSHLEENKTTCLQKQEVYEDYKSYCMTYNIKCLSTADFGKVMKKNFPNIKARRLGARGQSRYCYSGLRNRQETQSPALKDIGM 788
            L+  +++    KV  I+  +   SD +KL + LQ P   S       S ++  N  D         Q     W+ SHLEE+  TCL KQ+VYE Y+ +C     + LS A+FGK+++  FPNIKARRLG RGQS+YCYSG+R +     P L ++ +
Sbjct:   26 LKSNISKSVQNKVDTILRDVQQFSDNDKLYLYLQLPSGPSAGEKSGDSNSV--NTAD---------QLHTCNWIRSHLEEHADTCLPKQDVYETYRKHCENLQQRPLSAANFGKIIRDIFPNIKARRLGGRGQSKYCYSGIRRKTVLNMPLLPNLDL 171

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BLAST of RFX-type winged-helix domain-containing protein vs. Ensembl Cavefish
Match: rfx5 (regulatory factor X5 [Source:NCBI gene;Acc:103044951])

HSP 1 Score: 110.923 bits (276), Expect = 2.253e-25
Identity = 56/138 (40.58%), Postives = 77/138 (55.80%), Query Frame = 3

Query:  375 ILNLSDTEKLLIQLQFPMTESDNGTFDSSMNIGFNNVDILGNSTIVEQEEASKWVLSHLEENKTTCLQKQEVYEDYKSYCMTYNIKCLSTADFGKVMKKNFPNIKARRLGARGQSRYCYSGLRNRQETQSPALKDIGM 788
            +   SD +KL + LQ P   S       S ++  N  D         Q     W+ SHLEE+  TCL KQ+VYE Y+ +C     + LS A+FGK+++  FPNIKARRLG RGQS+YCYSG+R +     P L ++ +
Sbjct:   21 VQQFSDNDKLYLYLQLPSGPSAGEKSGDSNSV--NTAD---------QLHTCNWIRSHLEEHADTCLPKQDVYETYRKHCENLQQRPLSAANFGKIIRDIFPNIKARRLGGRGQSKYCYSGIRRKTVLNMPLLPNLDL 147

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BLAST of RFX-type winged-helix domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000005569.1 (pep scaffold:Pmarinus_7.0:GL484170:9855:13247:-1 gene:ENSPMAG00000005066.1 transcript:ENSPMAT00000005569.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 103.99 bits (258), Expect = 3.409e-26
Identity = 50/99 (50.51%), Postives = 67/99 (67.68%), Query Frame = 3

Query:  513 EQEEASKWVLSHLEENKTTCLQKQEVYEDYKSYCMTYNIKCLSTADFGKVMKKNFPNIKARRLGARGQSRY--CYSGLRNRQETQSPALKDIGMVLEGN 803
            +Q +A  W+  HLEE+  T L KQEVY++YK YC     + LS ADFGK+MK  FPN+KARRLG RG S+Y  CYSGLR +   Q+P+L  + +  +G+
Sbjct:   12 DQMQAFSWIRQHLEEHNDTSLPKQEVYDEYKGYCENLGHRFLSAADFGKLMKNVFPNMKARRLGTRGNSKYPCCYSGLRKKALVQTPSLPSLEVGKKGD 110

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BLAST of RFX-type winged-helix domain-containing protein vs. Ensembl Sea Lamprey
Match: rfx2 (regulatory factor X, 2 (influences HLA class II expression) [Source:NCBI gene;Acc:503590])

HSP 1 Score: 53.9138 bits (128), Expect = 6.693e-8
Identity = 22/71 (30.99%), Postives = 40/71 (56.34%), Query Frame = 3

Query:  531 KWVLSHLEENKTTCLQKQEVYEDYKSYCMTYNIKCLSTADFGKVMKKNFPNIKARRLGARGQSRYCYSGLR 743
            +W++ + E  +   L +  +Y  Y  +C    +  ++ A FGK+++  F  ++ RRLG RG S+Y Y G+R
Sbjct:  187 QWLIDNYETAEGVSLPRCTLYNHYLRHCQEQKLDPVNAASFGKLIRSVFLGLRTRRLGTRGNSKYHYYGIR 257

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BLAST of RFX-type winged-helix domain-containing protein vs. Ensembl Yeast
Match: RFX1 (Major transcriptional repressor of DNA-damage-regulated genes; recruits repressors Tup1p and Cyc8p to their promoters; involved in DNA damage and replication checkpoint pathway; similar to a family of mammalian DNA binding RFX1-4 proteins [Source:SGD;Acc:S000004166])

HSP 1 Score: 63.5438 bits (153), Expect = 4.308e-11
Identity = 27/76 (35.53%), Postives = 45/76 (59.21%), Query Frame = 3

Query:  516 QEEASKWVLSHLEENKTTCLQKQEVYEDYKSYCMTYNIKCLSTADFGKVMKKNFPNIKARRLGARGQSRYCYSGLR 743
            Q  A  W++ + +    + + + +++  Y S C   N+K LS A  GK+++  FP++  RRLG RGQS+Y Y GL+
Sbjct:  282 QVFALLWLMKNCKSQHDSYVPRGKIFAQYASSCSQNNLKPLSQASLGKLIRTVFPDLTTRRLGMRGQSKYHYCGLK 357

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BLAST of RFX-type winged-helix domain-containing protein vs. Ensembl Nematostella
Match: EDO41435 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S491])

HSP 1 Score: 103.605 bits (257), Expect = 2.204e-25
Identity = 58/138 (42.03%), Postives = 86/138 (62.32%), Query Frame = 3

Query:  375 ILNLSDTEKLLIQLQFPMTESDNGTFDSSMNIGFNNVDILGNSTIVEQEEASKWVLSHLEE-NKTTCLQKQEVYEDYKSYCMTYNI-KCLSTADFGKVMKKNFPNIKARRLGARGQSRYCYSGLRNRQETQSPALKDI 782
            +  LSDTEKLL+ L+ P  ES + T D        N  +  ++T  EQ +A  W+  HLEE + ++ L K EVY++YK+YC + +  + LS  DFGK++K  FP +KARRLG RG S+YCYSG++ ++  + P L  +
Sbjct:    3 VQQLSDTEKLLLYLRLP-GESCSETKDEFEQ----NQGLPISTTRAEQTQAFHWIRCHLEECDNSSTLPKHEVYDEYKAYCESMSASRTLSAPDFGKIIKCVFPRVKARRLGTRGNSKYCYSGIQRKKNVKPPTLPSL 135

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BLAST of RFX-type winged-helix domain-containing protein vs. Ensembl Nematostella
Match: EDO43982 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RX75])

HSP 1 Score: 61.2326 bits (147), Expect = 4.887e-10
Identity = 28/87 (32.18%), Postives = 49/87 (56.32%), Query Frame = 3

Query:  531 KWVLSHLEENKTTCLQKQEVYEDYKSYCMTYNIKCLSTADFGKVMKKNFPNIKARRLGARGQSRYCYSGLRNRQETQSPALKDIGMV 791
            +W+L + E  +   L +  +Y  Y ++C T+ +  ++ A FGK+++  F  ++ RRLG RG S+Y Y G+R +  +   AL D   V
Sbjct:    2 QWLLENYETAEGVSLPRSTLYNHYLTHCQTHKLDPVNAASFGKLIRSVFLGLRTRRLGTRGNSKYHYYGIRIKPSSPLNALTDDAQV 88

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BLAST of RFX-type winged-helix domain-containing protein vs. Ensembl Nematostella
Match: EDO35375 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SLM7])

HSP 1 Score: 58.9214 bits (141), Expect = 2.184e-9
Identity = 23/56 (41.07%), Postives = 36/56 (64.29%), Query Frame = 3

Query:  573 LQKQEVYEDYKSYCMTYNIKCLSTADFGKVMKKNFPNIKARRLGARGQSRYCYSGL 740
            L +  +Y  Y  +C   ++  ++ A FGK+++  FPN+K RRLG RGQS+Y Y G+
Sbjct:   13 LPRSALYSHYLDFCEKNSLSPVNAASFGKIIRHTFPNLKTRRLGTRGQSKYHYYGI 68

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BLAST of RFX-type winged-helix domain-containing protein vs. Ensembl Nematostella
Match: EDO47852 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RL05])

HSP 1 Score: 55.8398 bits (133), Expect = 2.290e-8
Identity = 22/58 (37.93%), Postives = 33/58 (56.90%), Query Frame = 3

Query:  567 TCLQKQEVYEDYKSYCMTYNIKCLSTADFGKVMKKNFPNIKARRLGARGQSRYCYSGL 740
             CL +  +Y  Y  +C  + I+    A FGK +++ FP +  RRLG RG S+Y Y G+
Sbjct:   11 VCLPRCILYAHYLDFCRRHKIEAACAATFGKTIRQKFPQLTTRRLGTRGHSKYHYYGI 68

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BLAST of RFX-type winged-helix domain-containing protein vs. Ensembl Nematostella
Match: EDO39490 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S9V5])

HSP 1 Score: 54.6842 bits (130), Expect = 4.277e-8
Identity = 23/64 (35.94%), Postives = 36/64 (56.25%), Query Frame = 3

Query:  552 EENKTTCLQKQEVYEDYKSYCMTYNIKCLSTADFGKVMKKNFPNIKARRLGARGQSRYCYSGLR 743
            E  +  CL +  +Y  Y  +C    +     A FGK++++ FP +  RRLG RGQS+Y Y G++
Sbjct:    6 ELKEGMCLPRCVMYTHYLDFCKKNKLNPAGPATFGKIIRQKFPKLTTRRLGTRGQSKYHYYGIQ 69

[Close]

BLAST of RFX-type winged-helix domain-containing protein vs. Ensembl Medaka
Match: rfx5 (regulatory factor X5 [Source:NCBI gene;Acc:101161817])

HSP 1 Score: 125.561 bits (314), Expect = 4.558e-30
Identity = 66/157 (42.04%), Postives = 89/157 (56.69%), Query Frame = 3

Query:  318 LEKTLTEDKSTKVKEIISQILNLSDTEKLLIQLQFPMTESDNGTFDSSMNIGFNNVDILGNSTIVEQEEASKWVLSHLEENKTTCLQKQEVYEDYKSYCMTYNIKCLSTADFGKVMKKNFPNIKARRLGARGQSRYCYSGLRNRQETQSPALKDIGM 788
            L+  +++D  TKV +I+  +   SD +KL + LQ P     N    SS +  FN  D         Q     W+ SHLEE+  TCL KQ+VYE YK YC     + LS A FGK+++  FPNIKARRLG RGQS+YCYSG+R +     P L ++ +
Sbjct:   36 LKSNISKDVQTKVDQILQDVQRFSDGDKLYLYLQLP--SGPNSGDKSSDSSSFNTAD---------QLHTCNWIRSHLEEHSDTCLPKQDVYEAYKRYCKNLRHRPLSAAIFGKIIRDIFPNIKARRLGGRGQSKYCYSGIRRKTVLNMPLLPNLDL 181

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BLAST of RFX-type winged-helix domain-containing protein vs. Ensembl Medaka
Match: rfx7b (DNA-binding protein RFX7 [Source:NCBI gene;Acc:101161970])

HSP 1 Score: 120.939 bits (302), Expect = 2.504e-28
Identity = 63/163 (38.65%), Postives = 96/163 (58.90%), Query Frame = 3

Query:  318 LEKTLTEDKSTKVKEIISQILNLSDTEKLLIQLQFPMT-ESDNGTFDSSMNIGFNNVDILGNSTIVEQEEASKWVLSHLEENKTTCLQKQEVYEDYKSYCMTYNIKCLSTADFGKVMKKNFPNIKARRLGARGQSRYCYSGLRNRQETQSPALKDIGMVLEGN 803
            ++ ++ +   +KV  I+  +   +D EKL + L+ P    S N   + +   G  +   + +S+  +Q  A  W+ +HLEE+  T L KQEVY++YKSYC       LS ADFGK+MK  FPN+KARRLG RG+S+YCYSGLR +     P+L ++ +   G+
Sbjct:   38 IKNSICKSVQSKVDGILQDVEKFTDIEKLYLYLKLPSGPSSGNDKREGTSTPGLCDQSSM-SSSRTQQMYAFNWIRNHLEEHPETSLPKQEVYDEYKSYCDNLGYNPLSAADFGKIMKNVFPNMKARRLGMRGKSKYCYSGLRKKAFVHMPSLPNLDLQKSGD 199

[Close]

BLAST of RFX-type winged-helix domain-containing protein vs. Ensembl Medaka
Match: rfx7b (DNA-binding protein RFX7 [Source:NCBI gene;Acc:101161970])

HSP 1 Score: 116.316 bits (290), Expect = 9.547e-27
Identity = 63/162 (38.89%), Postives = 94/162 (58.02%), Query Frame = 3

Query:  318 LEKTLTEDKSTKVKEIISQILNLSDTEKLLIQLQFPMTESDNGTFDSSMNIGFNNVDILGNSTIVEQEEASKWVLSHLEENKTTCLQKQEVYEDYKSYCMTYNIKCLSTADFGKVMKKNFPNIKARRLGARGQSRYCYSGLRNRQETQSPALKDIGMVLEGN 803
            ++ ++ +   +KV  I+  +   +D EKL + L+ P       +  SS N   +   +  + T  +Q  A  W+ +HLEE+  T L KQEVY++YKSYC       LS ADFGK+MK  FPN+KARRLG RG+S+YCYSGLR +     P+L ++ +   G+
Sbjct:   38 IKNSICKSVQSKVDGILQDVEKFTDIEKLYLYLKLP-------SGPSSGNDKSDQSSMSSSRT--QQMYAFNWIRNHLEEHPETSLPKQEVYDEYKSYCDNLGYNPLSAADFGKIMKNVFPNMKARRLGMRGKSKYCYSGLRKKAFVHMPSLPNLDLQKSGD 190

[Close]

BLAST of RFX-type winged-helix domain-containing protein vs. Ensembl Medaka
Match: rfx4 (regulatory factor X4 [Source:NCBI gene;Acc:101165053])

HSP 1 Score: 59.6918 bits (143), Expect = 5.842e-9
Identity = 41/152 (26.97%), Postives = 71/152 (46.71%), Query Frame = 3

Query:  492 LGNSTIVEQEE-----ASK---------WVLSHLEENKTTCLQKQEVYEDYKSYCMTYNIKCLSTADFGKVMKKNFPNIKARRLGARGQSRYCYSGLRNRQETQSPALKDIGMVLEGNDTADDYRKRDNVANSEVESYSSTSVLNNDLSNVP 905
            LGN +  E EE     ASK         W+  + E  +  C+ +  +Y  Y  +   ++ + ++ A FGK++++ FP +  RRLG RGQS+Y Y G+  +   +S    D+    +G    ++  K++     +  +YS  S L   L   P
Sbjct:   36 LGNLSTDEHEEKENNRASKPHSTPATLEWLEENYEIAEGVCIPRSALYMHYLDFSEKHDTQPVNAASFGKIIRQQFPALTTRRLGTRGQSKYHYYGIAVK---ESSPYYDVMYSKKGAAWVNETGKKE--VTKQTVAYSPRSKLGTLLPEFP 182

[Close]

BLAST of RFX-type winged-helix domain-containing protein vs. Ensembl Medaka
Match: rfx1a (MHC class II regulatory factor RFX1 [Source:NCBI gene;Acc:101166798])

HSP 1 Score: 58.151 bits (139), Expect = 1.554e-8
Identity = 29/88 (32.95%), Postives = 47/88 (53.41%), Query Frame = 3

Query:  504 TIVEQEEAS--------KWVLSHLEENKTTCLQKQEVYEDYKSYCMTYNIKCLSTADFGKVMKKNFPNIKARRLGARGQSRYCYSGLR 743
            +I E EE S        +W+L + E  +   L +  +Y  Y  +C    ++ ++ A FGK+++  F  ++ RRLG RG S+Y Y GLR
Sbjct:  347 SITEGEETSVPSADKKVQWLLDNYETAEGVSLPRSTLYCHYLLHCQEQKLEPVNAASFGKLIRSVFMGLRTRRLGTRGNSKYHYYGLR 434

[Close]

BLAST of RFX-type winged-helix domain-containing protein vs. Planmine SMEST
Match: SMESG000021065.1 (SMESG000021065.1)

HSP 1 Score: 934.48 bits (2414), Expect = 0.000e+0
Identity = 478/479 (99.79%), Postives = 479/479 (100.00%), Query Frame = 3

Query:   72 MNNIHSYQDKIDLPDSGGLRLVENYSGSTSSAYDEVSPHMHNSTPGSSESIYEKHNQXXXXXXXXXXXXXXXXXXXXXTVDALEKTLTEDKSTKVKEIISQILNLSDTEKLLIQLQFPMTESDNGTFDSSMNIGFNNVDILGNSTIVEQEEASKWVLSHLEENKTTCLQKQEVYEDYKSYCMTYNIKCLSTADFGKVMKKNFPNIKARRLGARGQSRYCYSGLRNRQETQSPALKDIGMVLEGNDTADDYRKRDNVANSEVESYSSTSVLNNDLSNVPEYELSPNILIDSALVIIEFIKQVAMNKNIMSLKQAVKHLLSNSQVDMRSPHALRLCSIFHQVDGQKLYPINKYSADSIKKEETLVSPCSVTPQRSSTSSPQNQKRRDMFSSPVPNKMVYCDLPKSQSDNSPINTSQTINNPRSNYTYNQPYYHLHPNMLTMPHPMPLNPMRSDLSPASSLSNGTQHKSFVHSTPVKNLTNV 1508
            MNNIHSYQDKIDLPDSGGLRLVENYSGSTSSAYDEVSPHMHNSTPGSSESIYEKHNQSNVSSKKSKNSNLSNEDNLNLTVDALEKTLTEDKSTKVKEIISQILNLSDTEKLLIQLQFPMTESDNGTFDSSMNIGFNNVDILGNSTIVEQEEASKWVLSHLEENKTTCLQKQEVYEDYKSYCMTYNIKCLSTADFGKVMKKNFPNIKARRLGARGQSRYCYSGLRNRQETQSPALKDIGMVLEGNDTADDYRKRDNVANSEVESYSSTSVLNNDLSNVPEYELSPNILIDSALVIIEFIKQVAMNKNIMSLKQAVKHLLSNSQVDMRSPHALRLCSIFHQVDGQKLYPINKYSADSIKKEETLVSPCSVTPQRSSTSSPQNQKRRDMFSSPVPNKMVYCDLPKSQSDNSPINTSQTINNPRSNYTYNQPYYHLHPNMLTMPHPMPLNPMRSDLSPASSLSNGTQHKSFVHSTPVKNLTN+
Sbjct:    1 MNNIHSYQDKIDLPDSGGLRLVENYSGSTSSAYDEVSPHMHNSTPGSSESIYEKHNQSNVSSKKSKNSNLSNEDNLNLTVDALEKTLTEDKSTKVKEIISQILNLSDTEKLLIQLQFPMTESDNGTFDSSMNIGFNNVDILGNSTIVEQEEASKWVLSHLEENKTTCLQKQEVYEDYKSYCMTYNIKCLSTADFGKVMKKNFPNIKARRLGARGQSRYCYSGLRNRQETQSPALKDIGMVLEGNDTADDYRKRDNVANSEVESYSSTSVLNNDLSNVPEYELSPNILIDSALVIIEFIKQVAMNKNIMSLKQAVKHLLSNSQVDMRSPHALRLCSIFHQVDGQKLYPINKYSADSIKKEETLVSPCSVTPQRSSTSSPQNQKRRDMFSSPVPNKMVYCDLPKSQSDNSPINTSQTINNPRSNYTYNQPYYHLHPNMLTMPHPMPLNPMRSDLSPASSLSNGTQHKSFVHSTPVKNLTNL 479

[Close]

BLAST of RFX-type winged-helix domain-containing protein vs. Planmine SMEST
Match: SMESG000058756.1 (SMESG000058756.1)

HSP 1 Score: 68.1662 bits (165), Expect = 6.498e-12
Identity = 32/86 (37.21%), Postives = 53/86 (61.63%), Query Frame = 3

Query:  540 LSHLEEN----KTTCLQKQEVYEDYKSYCMTYNIKCLSTADFGKVMKKNFPNIKARRLGARGQSRYCYSGLRNRQETQSPALKDIG 785
            +S L+EN    +   L ++ +YE+Y+S+C ++    +STA FGK++++ FP I  RRLG RG S+Y Y GL  ++ +      +IG
Sbjct:   18 ISWLKENYCFVEGVSLSRKTLYENYQSFCRSHVYSQISTATFGKIIRQQFPQITTRRLGTRGNSKYHYHGLAVKKSSVYFNFNNIG 103

[Close]

BLAST of RFX-type winged-helix domain-containing protein vs. Planmine SMEST
Match: SMESG000017202.1 (SMESG000017202.1)

HSP 1 Score: 55.8398 bits (133), Expect = 8.140e-8
Identity = 22/71 (30.99%), Postives = 39/71 (54.93%), Query Frame = 3

Query:  531 KWVLSHLEENKTTCLQKQEVYEDYKSYCMTYNIKCLSTADFGKVMKKNFPNIKARRLGARGQSRYCYSGLR 743
            +W+  + E      L +  +Y  Y  +C    ++ ++ A FGK+++  F  ++ RRLG RG S+Y Y G+R
Sbjct:  195 QWLYDNYETADGVSLPRSTLYNHYLQHCQQEKLEPMNQASFGKLIRSVFFGLRTRRLGTRGNSKYHYYGIR 265

The following BLAST results are available for this feature:

BLAST of RFX-type winged-helix domain-containing protein vs. Ensembl Human
BLAST of RFX-type winged-helix domain-containing protein vs. Ensembl Celegans
BLAST of RFX-type winged-helix domain-containing protein vs. Ensembl Fly
BLAST of RFX-type winged-helix domain-containing protein vs. Ensembl Zebrafish
BLAST of RFX-type winged-helix domain-containing protein vs. Ensembl Xenopus
BLAST of RFX-type winged-helix domain-containing protein vs. Ensembl Mouse
BLAST of RFX-type winged-helix domain-containing protein vs. UniProt/SwissProt
BLAST of RFX-type winged-helix domain-containing protein vs. TrEMBL
BLAST of RFX-type winged-helix domain-containing protein vs. Ensembl Cavefish
BLAST of RFX-type winged-helix domain-containing protein vs. Ensembl Sea Lamprey
BLAST of RFX-type winged-helix domain-containing protein vs. Ensembl Yeast
BLAST of RFX-type winged-helix domain-containing protein vs. Ensembl Nematostella
BLAST of RFX-type winged-helix domain-containing protein vs. Ensembl Medaka
BLAST of RFX-type winged-helix domain-containing protein vs. Planmine SMEST

BLAST of RFX-type winged-helix domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
RFX5	2.810e-28	39.76	regulatory factor X5 [Source:HGNC Symbol;Acc:HGNC:...	[more]
RFX5	6.873e-28	39.05	regulatory factor X5 [Source:HGNC Symbol;Acc:HGNC:...	[more]
RFX7	1.293e-27	39.52	regulatory factor X7 [Source:HGNC Symbol;Acc:HGNC:...	[more]
RFX5	2.276e-27	30.68	regulatory factor X5 [Source:HGNC Symbol;Acc:HGNC:...	[more]
RFX5	2.276e-27	30.68	regulatory factor X5 [Source:HGNC Symbol;Acc:HGNC:...	[more]

BLAST of RFX-type winged-helix domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
daf-19	1.244e-9	37.14	RFX-like transcription factor daf-19 [Source:UniP...	[more]
daf-19	1.316e-9	37.14	RFX-like transcription factor daf-19 [Source:UniP...	[more]
daf-19	1.458e-9	37.14	RFX-like transcription factor daf-19 [Source:UniP...	[more]
daf-19	1.559e-9	37.14	RFX-like transcription factor daf-19 [Source:UniP...	[more]
daf-19	1.812e-9	37.14	RFX-like transcription factor daf-19 [Source:UniP...	[more]

BLAST of RFX-type winged-helix domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
CG9727	9.215e-26	36.71	gene:FBgn0037445 transcript:FBtr0330193	[more]
CG9727	9.215e-26	36.71	gene:FBgn0037445 transcript:FBtr0081730	[more]
CG9727	9.879e-26	36.71	gene:FBgn0037445 transcript:FBtr0330192	[more]
Rfx	2.343e-8	29.59	gene:FBgn0020379 transcript:FBtr0337107	[more]
Rfx	2.361e-8	29.59	gene:FBgn0020379 transcript:FBtr0337105	[more]

BLAST of RFX-type winged-helix domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
rfx7a	2.801e-29	36.67	regulatory factor X7a [Source:ZFIN;Acc:ZDB-GENE-10...	[more]
rfx7b	2.012e-27	39.75	regulatory factor X7b [Source:ZFIN;Acc:ZDB-GENE-17...	[more]
rfx5	6.787e-27	38.22	regulatory factor X, 5 [Source:NCBI gene;Acc:10188...	[more]
rfx4	2.213e-10	26.40	regulatory factor X, 4 [Source:NCBI gene;Acc:40301...	[more]
rfx4	2.213e-10	26.40	regulatory factor X, 4 [Source:NCBI gene;Acc:40301...	[more]

BLAST of RFX-type winged-helix domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
rfx7	5.539e-25	44.09	regulatory factor X7 [Source:NCBI gene;Acc:1000382...	[more]
rfx7	9.123e-21	41.09	regulatory factor X7 [Source:NCBI gene;Acc:1000382...	[more]
rfx2	1.463e-8	32.39	regulatory factor X2 [Source:NCBI gene;Acc:1001447...	[more]
rfx2	1.498e-8	32.39	regulatory factor X2 [Source:NCBI gene;Acc:1001447...	[more]
rfx2	1.597e-8	32.39	regulatory factor X2 [Source:NCBI gene;Acc:1001447...	[more]

BLAST of RFX-type winged-helix domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Rfx5	3.427e-30	30.16	regulatory factor X, 5 (influences HLA class II ex...	[more]
Rfx5	3.427e-30	30.16	regulatory factor X, 5 (influences HLA class II ex...	[more]
Rfx5	5.436e-29	30.16	regulatory factor X, 5 (influences HLA class II ex...	[more]
Rfx5	5.436e-29	30.16	regulatory factor X, 5 (influences HLA class II ex...	[more]
Rfx5	5.436e-29	30.16	regulatory factor X, 5 (influences HLA class II ex...	[more]

BLAST of RFX-type winged-helix domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q9JL61\|RFX5_MOUSE	3.802e-28	30.16	DNA-binding protein Rfx5 OS=Mus musculus OX=10090 ...	[more]
sp\|P48382\|RFX5_HUMAN	1.093e-26	30.68	DNA-binding protein RFX5 OS=Homo sapiens OX=9606 G...	[more]
sp\|Q2KHR2\|RFX7_HUMAN	4.298e-24	46.15	DNA-binding protein RFX7 OS=Homo sapiens OX=9606 G...	[more]
sp\|P48383\|SAK1_SCHPO	1.573e-11	37.65	Protein sak1 OS=Schizosaccharomyces pombe (strain ...	[more]
sp\|Q7TNK1\|RFX4_MOUSE	1.028e-9	27.20	Transcription factor RFX4 OS=Mus musculus OX=10090...	[more]

BLAST of RFX-type winged-helix domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A158R985	2.254e-43	34.39	RFX-type winged-helix domain-containing protein OS...	[more]
A0A0R3WI66	2.532e-43	34.15	RFX-type winged-helix domain-containing protein OS...	[more]
A0A5K3ERA4	2.712e-43	36.40	Uncharacterized protein OS=Mesocestoides corti OX=...	[more]
A0A0R3TU13	3.250e-43	38.21	RFX-type winged-helix domain-containing protein OS...	[more]
A0A5K3EPU5	5.364e-43	36.40	Uncharacterized protein OS=Mesocestoides corti OX=...	[more]

BLAST of RFX-type winged-helix domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
rfx7b	8.086e-28	39.51	regulatory factor X7b [Source:ZFIN;Acc:ZDB-GENE-17...	[more]
rfx7b	3.126e-27	38.01	regulatory factor X7b [Source:ZFIN;Acc:ZDB-GENE-17...	[more]
rfx7a	4.701e-27	35.79	DNA-binding protein RFX7-like [Source:NCBI gene;Ac...	[more]
rfx5	8.165e-27	38.22	regulatory factor X5 [Source:NCBI gene;Acc:1030449...	[more]
rfx5	2.253e-25	40.58	regulatory factor X5 [Source:NCBI gene;Acc:1030449...	[more]

BLAST of RFX-type winged-helix domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 2


Match Name	E-value	Identity	Description
ENSPMAT00000005569.1	3.409e-26	50.51	pep scaffold:Pmarinus_7.0:GL484170:9855:13247:-1 g...	[more]
rfx2	6.693e-8	30.99	regulatory factor X, 2 (influences HLA class II ex...	[more]

BLAST of RFX-type winged-helix domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1


Match Name	E-value	Identity	Description
RFX1	4.308e-11	35.53	Major transcriptional repressor of DNA-damage-regu...	[more]

BLAST of RFX-type winged-helix domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO41435	2.204e-25	42.03	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO43982	4.887e-10	32.18	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO35375	2.184e-9	41.07	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO47852	2.290e-8	37.93	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO39490	4.277e-8	35.94	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of RFX-type winged-helix domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
rfx5	4.558e-30	42.04	regulatory factor X5 [Source:NCBI gene;Acc:1011618...	[more]
rfx7b	2.504e-28	38.65	DNA-binding protein RFX7 [Source:NCBI gene;Acc:101...	[more]
rfx7b	9.547e-27	38.89	DNA-binding protein RFX7 [Source:NCBI gene;Acc:101...	[more]
rfx4	5.842e-9	26.97	regulatory factor X4 [Source:NCBI gene;Acc:1011650...	[more]
rfx1a	1.554e-8	32.95	MHC class II regulatory factor RFX1 [Source:NCBI g...	[more]

BLAST of RFX-type winged-helix domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 3


Match Name	E-value	Identity	Description
SMESG000021065.1	0.000e+0	99.79	SMESG000021065.1	[more]
SMESG000058756.1	6.498e-12	37.21	SMESG000058756.1	[more]
SMESG000017202.1	8.140e-8	30.99	SMESG000017202.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30018240 ID=SMED30018240|Name=RFX-type winged-helix domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=1601bp
TATAAGTGAACTCAAATTGGTCTTGAATTTTAACCTTTATTCTTTAAATT
ATTTTCTTGAGAATAGGTTTCATGAATAATATACACAGTTATCAAGACAA
GATTGATTTGCCTGATAGTGGAGGTCTTAGGCTTGTAGAAAATTATAGTG
GGAGTACAAGTTCAGCGTATGACGAAGTTAGTCCACATATGCACAATAGT
ACTCCAGGTAGTAGTGAGAGCATCTATGAAAAACACAATCAATCTAATGT
TTCATCTAAAAAATCAAAAAATTCCAACTTATCAAATGAAGACAATTTAA
ATTTAACTGTTGATGCGTTGGAAAAAACATTAACAGAAGATAAATCCACC
AAAGTTAAAGAAATTATATCACAAATTCTGAATTTATCCGACACTGAGAA
ATTATTGATACAACTCCAATTTCCAATGACAGAATCCGACAATGGAACTT
TTGATTCATCGATGAATATTGGTTTTAACAATGTTGATATACTTGGAAAT
AGCACGATAGTTGAACAAGAGGAAGCATCGAAATGGGTTTTATCACACTT
AGAAGAAAATAAAACTACTTGTTTACAAAAACAAGAAGTATATGAAGATT
ACAAATCATACTGTATGACGTATAACATCAAATGTTTGAGTACAGCCGAT
TTTGGAAAGGTAATGAAGAAGAATTTTCCAAACATCAAAGCCCGTCGGTT
AGGAGCAAGAGGACAATCGAGGTATTGTTATTCTGGATTAAGAAATCGAC
AAGAAACCCAATCACCGGCATTGAAAGATATCGGTATGGTGCTCGAAGGC
AATGACACTGCCGATGATTATCGAAAACGAGACAATGTTGCAAACAGTGA
AGTCGAATCTTATTCATCCACATCAGTGTTGAATAATGATTTATCGAATG
TTCCAGAATACGAGCTCAGTCCGAATATTTTAATCGATTCTGCACTTGTT
ATCATTGAATTCATTAAACAAGTTGCAATGAATAAAAACATAATGAGTCT
GAAGCAAGCCGTTAAACATTTATTGTCCAATAGTCAAGTCGATATGCGTT
CACCACATGCTTTGAGACTGTGCTCGATTTTCCACCAAGTTGACGGCCAA
AAGCTCTATCCAATAAATAAATATTCAGCGGATTCCATTAAAAAAGAAGA
GACCCTTGTTAGTCCATGTAGCGTAACACCTCAAAGATCATCTACATCTA
GTCCTCAGAACCAAAAACGCCGTGATATGTTTAGTTCGCCGGTACCAAAT
AAAATGGTATATTGTGATTTACCAAAATCCCAGTCAGATAATTCTCCTAT
TAACACATCTCAAACCATTAATAATCCCAGATCTAATTACACATATAATC
AGCCCTATTATCATTTGCATCCTAACATGTTAACGATGCCACATCCAATG
CCTTTGAATCCAATGAGATCTGACTTATCCCCTGCGTCCAGTCTCAGTAA
TGGAACTCAACATAAGTCTTTTGTTCATTCAACACCAGTGAAAAACTTAA
CTAATGTAAGTTTCCTTATTTTATTTGTAATAATTTTTATACAATTGACA
ATATTTTAATCAGTATTATAATGGAAGCTTATACAAAATAAGTAGCATAA
T

protein sequence of SMED30018240-orf-1

>SMED30018240-orf-1 ID=SMED30018240-orf-1|Name=SMED30018240-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=496bp
MNNIHSYQDKIDLPDSGGLRLVENYSGSTSSAYDEVSPHMHNSTPGSSES
IYEKHNQSNVSSKKSKNSNLSNEDNLNLTVDALEKTLTEDKSTKVKEIIS
QILNLSDTEKLLIQLQFPMTESDNGTFDSSMNIGFNNVDILGNSTIVEQE
EASKWVLSHLEENKTTCLQKQEVYEDYKSYCMTYNIKCLSTADFGKVMKK
NFPNIKARRLGARGQSRYCYSGLRNRQETQSPALKDIGMVLEGNDTADDY
RKRDNVANSEVESYSSTSVLNNDLSNVPEYELSPNILIDSALVIIEFIKQ
VAMNKNIMSLKQAVKHLLSNSQVDMRSPHALRLCSIFHQVDGQKLYPINK
YSADSIKKEETLVSPCSVTPQRSSTSSPQNQKRRDMFSSPVPNKMVYCDL
PKSQSDNSPINTSQTINNPRSNYTYNQPYYHLHPNMLTMPHPMPLNPMRS
DLSPASSLSNGTQHKSFVHSTPVKNLTNVSFLILFVIIFIQLTIF*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **molecular function**
Term	Definition
GO:0003700	transcription factor activity, sequence-specific DNA binding
GO:0003677	DNA binding

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000420	parapharyngeal region
PLANA:0002109	X1 cell
PLANA:0002111	X2 cell

Vocabulary: **INTERPRO**
Term	Definition
IPR036388	WH-like_DNA-bd_sf
IPR039779	RFX-like
IPR036390	WH_DNA-bd_sf
IPR011991	WHTH_DNA-bd_dom
IPR003150	DNA-bd_RFX

Vocabulary: **biological process**
Term	Definition
GO:0006355	regulation of transcription, DNA-templated

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR036388	Winged helix-like DNA-binding domain superfamily	GENE3D	G3DSA:1.10.10.10		coord: 152..226 e-value: 3.6E-26 score: 93.5
IPR003150	DNA-binding RFX-type winged-helix domain	PFAM	PF02257	RFX_DNA_binding	coord: 152..226 e-value: 1.0E-26 score: 93.3
IPR003150	DNA-binding RFX-type winged-helix domain	PROSITE	PS51526	RFX_DBD	coord: 152..227 score: 19.655
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 362..387
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 362..388
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 30..73
None	No IPR available	PANTHER	PTHR12619:SF21		coord: 57..335
IPR039779	RFX-like DNA-binding protein	PANTHER	PTHR12619	RFX TRANSCRIPTION FACTOR FAMILY	coord: 57..335
IPR036390	Winged helix DNA-binding domain superfamily	SUPERFAMILY	SSF46785	"Winged helix" DNA-binding domain	coord: 154..225