Troponin C, skeletal muscle

Overview
NameTroponin C, skeletal muscle
Smed IDSMED30018233
Length (bp)1799
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Troponin C, skeletal muscle (SMED30018233) t-SNE clustered cells

Violin plots show distribution of expression levels for Troponin C, skeletal muscle (SMED30018233) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Troponin C, skeletal muscle (SMED30018233) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Troponin C, skeletal muscle (SMED30018233) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30018233

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 5

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
headSMED30018233SMESG000005066.1 SmedASXL_010127SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016
whole organism asexual adult RNA-sequencing evidence
neuronSMED30018233SMESG000005066.1 dd_Smed_v4_12048_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
whole organism asexual adult single-cell RNA-sequencing evidence
neuronSMED30018233SMESG000005066.1 dd_Smed_v4_12048_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
whole organism asexual adult colorimetric in situ hybridization evidence
headSMED30018233SMESG000005066.1 dd_Smed_v6_12048_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017
whole organism asexual adult RNA-sequencing evidence
headSMED30018233SMESG000005066.1 OX_Smed_1.0.08226ox_Smed_v2PMID:24238224
Kao et al., 2013
whole organism asexual adult RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of Troponin C, skeletal muscle vs. Ensembl Human
Match: CALM2 (calmodulin 2 [Source:HGNC Symbol;Acc:HGNC:1445])

HSP 1 Score: 110.538 bits (275), Expect = 9.823e-28
Identity = 61/146 (41.78%), Postives = 90/146 (61.64%), Query Frame = 2
Query:  911 KEIQKFRDAFDSVDTDSDGRISPEELKRAFTKLGNIVTETEILKMIKEVDIDRNGTVEFNEFVIMMHHYTKFRSDHQGNDSEDSDIYDAFKAFDHNGDGFIDSDEIKRTMVALGESVSDSDVMAMIFEADADKDGKINFNEFKKIM 1348
            ++I +F++AF   D D DG I+ +EL      LG   TE E+  MI EVD D NGT++F EF+ MM    K        DSE+ +I +AF+ FD +G+G+I + E++  M  LGE ++D +V  MI EAD D DG++N+ EF ++M
Sbjct:    8 EQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMK------DTDSEE-EIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 146          
BLAST of Troponin C, skeletal muscle vs. Ensembl Human
Match: CALM2 (calmodulin 2 [Source:HGNC Symbol;Acc:HGNC:1445])

HSP 1 Score: 110.538 bits (275), Expect = 9.823e-28
Identity = 61/146 (41.78%), Postives = 90/146 (61.64%), Query Frame = 2
Query:  911 KEIQKFRDAFDSVDTDSDGRISPEELKRAFTKLGNIVTETEILKMIKEVDIDRNGTVEFNEFVIMMHHYTKFRSDHQGNDSEDSDIYDAFKAFDHNGDGFIDSDEIKRTMVALGESVSDSDVMAMIFEADADKDGKINFNEFKKIM 1348
            ++I +F++AF   D D DG I+ +EL      LG   TE E+  MI EVD D NGT++F EF+ MM    K        DSE+ +I +AF+ FD +G+G+I + E++  M  LGE ++D +V  MI EAD D DG++N+ EF ++M
Sbjct:    8 EQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMK------DTDSEE-EIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 146          
BLAST of Troponin C, skeletal muscle vs. Ensembl Human
Match: CALM1 (calmodulin 1 [Source:HGNC Symbol;Acc:HGNC:1442])

HSP 1 Score: 110.538 bits (275), Expect = 9.823e-28
Identity = 61/146 (41.78%), Postives = 90/146 (61.64%), Query Frame = 2
Query:  911 KEIQKFRDAFDSVDTDSDGRISPEELKRAFTKLGNIVTETEILKMIKEVDIDRNGTVEFNEFVIMMHHYTKFRSDHQGNDSEDSDIYDAFKAFDHNGDGFIDSDEIKRTMVALGESVSDSDVMAMIFEADADKDGKINFNEFKKIM 1348
            ++I +F++AF   D D DG I+ +EL      LG   TE E+  MI EVD D NGT++F EF+ MM    K        DSE+ +I +AF+ FD +G+G+I + E++  M  LGE ++D +V  MI EAD D DG++N+ EF ++M
Sbjct:    8 EQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMK------DTDSEE-EIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 146          
BLAST of Troponin C, skeletal muscle vs. Ensembl Human
Match: CALM3 (calmodulin 3 [Source:HGNC Symbol;Acc:HGNC:1449])

HSP 1 Score: 110.538 bits (275), Expect = 9.823e-28
Identity = 61/146 (41.78%), Postives = 90/146 (61.64%), Query Frame = 2
Query:  911 KEIQKFRDAFDSVDTDSDGRISPEELKRAFTKLGNIVTETEILKMIKEVDIDRNGTVEFNEFVIMMHHYTKFRSDHQGNDSEDSDIYDAFKAFDHNGDGFIDSDEIKRTMVALGESVSDSDVMAMIFEADADKDGKINFNEFKKIM 1348
            ++I +F++AF   D D DG I+ +EL      LG   TE E+  MI EVD D NGT++F EF+ MM    K        DSE+ +I +AF+ FD +G+G+I + E++  M  LGE ++D +V  MI EAD D DG++N+ EF ++M
Sbjct:    8 EQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMK------DTDSEE-EIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 146          
BLAST of Troponin C, skeletal muscle vs. Ensembl Human
Match: CALM3 (calmodulin 3 [Source:HGNC Symbol;Acc:HGNC:1449])

HSP 1 Score: 110.538 bits (275), Expect = 9.823e-28
Identity = 61/146 (41.78%), Postives = 90/146 (61.64%), Query Frame = 2
Query:  911 KEIQKFRDAFDSVDTDSDGRISPEELKRAFTKLGNIVTETEILKMIKEVDIDRNGTVEFNEFVIMMHHYTKFRSDHQGNDSEDSDIYDAFKAFDHNGDGFIDSDEIKRTMVALGESVSDSDVMAMIFEADADKDGKINFNEFKKIM 1348
            ++I +F++AF   D D DG I+ +EL      LG   TE E+  MI EVD D NGT++F EF+ MM    K        DSE+ +I +AF+ FD +G+G+I + E++  M  LGE ++D +V  MI EAD D DG++N+ EF ++M
Sbjct:    8 EQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMK------DTDSEE-EIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 146          
BLAST of Troponin C, skeletal muscle vs. Ensembl Celegans
Match: cmd-1 (Calmodulin [Source:UniProtKB/Swiss-Prot;Acc:O16305])

HSP 1 Score: 110.538 bits (275), Expect = 3.531e-28
Identity = 62/146 (42.47%), Postives = 89/146 (60.96%), Query Frame = 2
Query:  911 KEIQKFRDAFDSVDTDSDGRISPEELKRAFTKLGNIVTETEILKMIKEVDIDRNGTVEFNEFVIMMHHYTKFRSDHQGNDSEDSDIYDAFKAFDHNGDGFIDSDEIKRTMVALGESVSDSDVMAMIFEADADKDGKINFNEFKKIM 1348
            ++I +F++AF   D D DG I+ +EL      LG   TE E+  MI EVD D NGT++F EF+ MM    K        DSE+ +I +AF+ FD +G+GFI + E++  M  LGE ++D +V  MI EAD D DG++N+ EF  +M
Sbjct:    8 EQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMK------DTDSEE-EIREAFRVFDKDGNGFISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVTMM 146          
BLAST of Troponin C, skeletal muscle vs. Ensembl Celegans
Match: cal-1 (Calmodulin-like protein [Source:UniProtKB/Swiss-Prot;Acc:P04630])

HSP 1 Score: 109.383 bits (272), Expect = 1.372e-27
Identity = 63/146 (43.15%), Postives = 87/146 (59.59%), Query Frame = 2
Query:  911 KEIQKFRDAFDSVDTDSDGRISPEELKRAFTKLGNIVTETEILKMIKEVDIDRNGTVEFNEFVIMMHHYTKFRSDHQGNDSEDSDIYDAFKAFDHNGDGFIDSDEIKRTMVALGESVSDSDVMAMIFEADADKDGKINFNEFKKIM 1348
            +EI +FR+AF   D D +G IS +EL  A   LG   TE EIL+MI EVDID NG +EF EF +MM    K        +++   I +AF+ FD +G+G I + E +  MV +G   S+ +V  MI E D D DG+I++ EF K+M
Sbjct:   21 EEIDEFREAFMMFDKDGNGTISTKELGIAMRSLGQNPTEQEILEMINEVDIDGNGQIEFPEFCVMMKRMMK--------ETDSEMIREAFRVFDKDGNGVITAQEFRYFMVHMGMQFSEEEVDEMIKEVDVDGDGEIDYEEFVKMM 158          
BLAST of Troponin C, skeletal muscle vs. Ensembl Celegans
Match: cal-1 (Calmodulin-like protein [Source:UniProtKB/Swiss-Prot;Acc:P04630])

HSP 1 Score: 108.997 bits (271), Expect = 2.398e-27
Identity = 63/146 (43.15%), Postives = 87/146 (59.59%), Query Frame = 2
Query:  911 KEIQKFRDAFDSVDTDSDGRISPEELKRAFTKLGNIVTETEILKMIKEVDIDRNGTVEFNEFVIMMHHYTKFRSDHQGNDSEDSDIYDAFKAFDHNGDGFIDSDEIKRTMVALGESVSDSDVMAMIFEADADKDGKINFNEFKKIM 1348
            +EI +FR+AF   D D +G IS +EL  A   LG   TE EIL+MI EVDID NG +EF EF +MM    K        +++   I +AF+ FD +G+G I + E +  MV +G   S+ +V  MI E D D DG+I++ EF K+M
Sbjct:   40 EEIDEFREAFMMFDKDGNGTISTKELGIAMRSLGQNPTEQEILEMINEVDIDGNGQIEFPEFCVMMKRMMK--------ETDSEMIREAFRVFDKDGNGVITAQEFRYFMVHMGMQFSEEEVDEMIKEVDVDGDGEIDYEEFVKMM 177          
BLAST of Troponin C, skeletal muscle vs. Ensembl Celegans
Match: cal-2 (CALmodulin related genes; Calmodulin-like protein [Source:UniProtKB/TrEMBL;Acc:G5EEG0])

HSP 1 Score: 105.145 bits (261), Expect = 4.668e-26
Identity = 62/144 (43.06%), Postives = 86/144 (59.72%), Query Frame = 2
Query:  905 NNKEIQKFRDAFDSVDTDSDGRISPEELKRAFTKLGNIVTETEILKMIKEVDIDRNGTVEFNEFVIMMHHYTKFRSDHQGNDSEDSDIYDAFKAFDHNGDGFIDSDEIKRTMVALGESVSDSDVMAMIFEADADKDGKINFNEF 1336
            N +EI +++ AF   D D +G IS +EL  A   LG   TE E+L M+ EVDID +GT++F EF  MM    K       NDSE   I +AF+ FD +G+GFI +DE +  M  +G+  SD +V  +I E D D DG+I++ EF
Sbjct:   30 NEEEIMEYKAAFRLFDKDGNGSISSKELGVAMRSLGQNPTEQELLDMVNEVDIDGSGTIDFGEFCQMMKRMNK------ENDSE--MIREAFRVFDRDGNGFITADEFRYFMTHMGDQFSDQEVDEIIAEIDIDGDGQIDYEEF 165          
BLAST of Troponin C, skeletal muscle vs. Ensembl Celegans
Match: cmd-1 (Calmodulin [Source:UniProtKB/Swiss-Prot;Acc:O16305])

HSP 1 Score: 90.5077 bits (223), Expect = 1.516e-21
Identity = 51/114 (44.74%), Postives = 71/114 (62.28%), Query Frame = 2
Query: 1007 LGNIVTETEILKMIKEVDIDRNGTVEFNEFVIMMHHYTKFRSDHQGNDSEDSDIYDAFKAFDHNGDGFIDSDEIKRTMVALGESVSDSDVMAMIFEADADKDGKINFNEFKKIM 1348
            LG   TE E+  MI EVD D NGT++F EF+ MM    K        DSE+ +I +AF+ FD +G+GFI + E++  M  LGE ++D +V  MI EAD D DG++N+ EF  +M
Sbjct:    4 LGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMK------DTDSEE-EIREAFRVFDKDGNGFISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVTMM 110          

HSP 2 Score: 56.6102 bits (135), Expect = 1.032e-9
Identity = 28/63 (44.44%), Postives = 40/63 (63.49%), Query Frame = 2
Query:  920 QKFRDAFDSVDTDSDGRISPEELKRAFTKLGNIVTETEILKMIKEVDIDRNGTVEFNEFVIMM 1108
            ++ R+AF   D D +G IS  EL+   T LG  +T+ E+ +MI+E DID +G V + EFV MM
Sbjct:   48 EEIREAFRVFDKDGNGFISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVTMM 110          
BLAST of Troponin C, skeletal muscle vs. Ensembl Fly
Match: Cam (gene:FBgn0000253 transcript:FBtr0304964)

HSP 1 Score: 110.538 bits (275), Expect = 4.224e-28
Identity = 62/146 (42.47%), Postives = 89/146 (60.96%), Query Frame = 2
Query:  911 KEIQKFRDAFDSVDTDSDGRISPEELKRAFTKLGNIVTETEILKMIKEVDIDRNGTVEFNEFVIMMHHYTKFRSDHQGNDSEDSDIYDAFKAFDHNGDGFIDSDEIKRTMVALGESVSDSDVMAMIFEADADKDGKINFNEFKKIM 1348
            ++I +F++AF   D D DG I+ +EL      LG   TE E+  MI EVD D NGT++F EF+ MM    K        DSE+ +I +AF+ FD +G+GFI + E++  M  LGE ++D +V  MI EAD D DG++N+ EF  +M
Sbjct:    8 EQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMK------DTDSEE-EIREAFRVFDKDGNGFISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVTMM 146          
BLAST of Troponin C, skeletal muscle vs. Ensembl Fly
Match: Cam (gene:FBgn0000253 transcript:FBtr0088001)

HSP 1 Score: 110.538 bits (275), Expect = 4.224e-28
Identity = 62/146 (42.47%), Postives = 89/146 (60.96%), Query Frame = 2
Query:  911 KEIQKFRDAFDSVDTDSDGRISPEELKRAFTKLGNIVTETEILKMIKEVDIDRNGTVEFNEFVIMMHHYTKFRSDHQGNDSEDSDIYDAFKAFDHNGDGFIDSDEIKRTMVALGESVSDSDVMAMIFEADADKDGKINFNEFKKIM 1348
            ++I +F++AF   D D DG I+ +EL      LG   TE E+  MI EVD D NGT++F EF+ MM    K        DSE+ +I +AF+ FD +G+GFI + E++  M  LGE ++D +V  MI EAD D DG++N+ EF  +M
Sbjct:    8 EQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMK------DTDSEE-EIREAFRVFDKDGNGFISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVTMM 146          
BLAST of Troponin C, skeletal muscle vs. Ensembl Fly
Match: Cam (gene:FBgn0000253 transcript:FBtr0304963)

HSP 1 Score: 110.538 bits (275), Expect = 4.224e-28
Identity = 62/146 (42.47%), Postives = 89/146 (60.96%), Query Frame = 2
Query:  911 KEIQKFRDAFDSVDTDSDGRISPEELKRAFTKLGNIVTETEILKMIKEVDIDRNGTVEFNEFVIMMHHYTKFRSDHQGNDSEDSDIYDAFKAFDHNGDGFIDSDEIKRTMVALGESVSDSDVMAMIFEADADKDGKINFNEFKKIM 1348
            ++I +F++AF   D D DG I+ +EL      LG   TE E+  MI EVD D NGT++F EF+ MM    K        DSE+ +I +AF+ FD +G+GFI + E++  M  LGE ++D +V  MI EAD D DG++N+ EF  +M
Sbjct:    8 EQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMK------DTDSEE-EIREAFRVFDKDGNGFISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVTMM 146          
BLAST of Troponin C, skeletal muscle vs. Ensembl Fly
Match: Cam (gene:FBgn0000253 transcript:FBtr0088002)

HSP 1 Score: 110.538 bits (275), Expect = 4.224e-28
Identity = 62/146 (42.47%), Postives = 89/146 (60.96%), Query Frame = 2
Query:  911 KEIQKFRDAFDSVDTDSDGRISPEELKRAFTKLGNIVTETEILKMIKEVDIDRNGTVEFNEFVIMMHHYTKFRSDHQGNDSEDSDIYDAFKAFDHNGDGFIDSDEIKRTMVALGESVSDSDVMAMIFEADADKDGKINFNEFKKIM 1348
            ++I +F++AF   D D DG I+ +EL      LG   TE E+  MI EVD D NGT++F EF+ MM    K        DSE+ +I +AF+ FD +G+GFI + E++  M  LGE ++D +V  MI EAD D DG++N+ EF  +M
Sbjct:    8 EQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMK------DTDSEE-EIREAFRVFDKDGNGFISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVTMM 146          
BLAST of Troponin C, skeletal muscle vs. Ensembl Fly
Match: Cam (gene:FBgn0000253 transcript:FBtr0345018)

HSP 1 Score: 110.538 bits (275), Expect = 4.224e-28
Identity = 62/146 (42.47%), Postives = 89/146 (60.96%), Query Frame = 2
Query:  911 KEIQKFRDAFDSVDTDSDGRISPEELKRAFTKLGNIVTETEILKMIKEVDIDRNGTVEFNEFVIMMHHYTKFRSDHQGNDSEDSDIYDAFKAFDHNGDGFIDSDEIKRTMVALGESVSDSDVMAMIFEADADKDGKINFNEFKKIM 1348
            ++I +F++AF   D D DG I+ +EL      LG   TE E+  MI EVD D NGT++F EF+ MM    K        DSE+ +I +AF+ FD +G+GFI + E++  M  LGE ++D +V  MI EAD D DG++N+ EF  +M
Sbjct:    8 EQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMK------DTDSEE-EIREAFRVFDKDGNGFISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVTMM 146          
BLAST of Troponin C, skeletal muscle vs. Ensembl Zebrafish
Match: calm2a (calmodulin 2a (phosphorylase kinase, delta) [Source:ZFIN;Acc:ZDB-GENE-030804-3])

HSP 1 Score: 110.538 bits (275), Expect = 5.341e-28
Identity = 61/146 (41.78%), Postives = 90/146 (61.64%), Query Frame = 2
Query:  911 KEIQKFRDAFDSVDTDSDGRISPEELKRAFTKLGNIVTETEILKMIKEVDIDRNGTVEFNEFVIMMHHYTKFRSDHQGNDSEDSDIYDAFKAFDHNGDGFIDSDEIKRTMVALGESVSDSDVMAMIFEADADKDGKINFNEFKKIM 1348
            ++I +F++AF   D D DG I+ +EL      LG   TE E+  MI EVD D NGT++F EF+ MM    K        DSE+ +I +AF+ FD +G+G+I + E++  M  LGE ++D +V  MI EAD D DG++N+ EF ++M
Sbjct:    8 EQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMK------DTDSEE-EIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 146          
BLAST of Troponin C, skeletal muscle vs. Ensembl Zebrafish
Match: calm3a (calmodulin 3a (phosphorylase kinase, delta) [Source:ZFIN;Acc:ZDB-GENE-030131-5590])

HSP 1 Score: 110.538 bits (275), Expect = 6.249e-28
Identity = 61/146 (41.78%), Postives = 90/146 (61.64%), Query Frame = 2
Query:  911 KEIQKFRDAFDSVDTDSDGRISPEELKRAFTKLGNIVTETEILKMIKEVDIDRNGTVEFNEFVIMMHHYTKFRSDHQGNDSEDSDIYDAFKAFDHNGDGFIDSDEIKRTMVALGESVSDSDVMAMIFEADADKDGKINFNEFKKIM 1348
            ++I +F++AF   D D DG I+ +EL      LG   TE E+  MI EVD D NGT++F EF+ MM    K        DSE+ +I +AF+ FD +G+G+I + E++  M  LGE ++D +V  MI EAD D DG++N+ EF ++M
Sbjct:    8 EQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMK------DTDSEE-EIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 146          
BLAST of Troponin C, skeletal muscle vs. Ensembl Zebrafish
Match: calm3b (calmodulin 3b (phosphorylase kinase, delta) [Source:ZFIN;Acc:ZDB-GENE-030131-527])

HSP 1 Score: 110.538 bits (275), Expect = 6.249e-28
Identity = 61/146 (41.78%), Postives = 90/146 (61.64%), Query Frame = 2
Query:  911 KEIQKFRDAFDSVDTDSDGRISPEELKRAFTKLGNIVTETEILKMIKEVDIDRNGTVEFNEFVIMMHHYTKFRSDHQGNDSEDSDIYDAFKAFDHNGDGFIDSDEIKRTMVALGESVSDSDVMAMIFEADADKDGKINFNEFKKIM 1348
            ++I +F++AF   D D DG I+ +EL      LG   TE E+  MI EVD D NGT++F EF+ MM    K        DSE+ +I +AF+ FD +G+G+I + E++  M  LGE ++D +V  MI EAD D DG++N+ EF ++M
Sbjct:    8 EQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMK------DTDSEE-EIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 146          
BLAST of Troponin C, skeletal muscle vs. Ensembl Zebrafish
Match: calm1b (calmodulin 1b [Source:ZFIN;Acc:ZDB-GENE-030804-2])

HSP 1 Score: 110.538 bits (275), Expect = 6.249e-28
Identity = 61/146 (41.78%), Postives = 90/146 (61.64%), Query Frame = 2
Query:  911 KEIQKFRDAFDSVDTDSDGRISPEELKRAFTKLGNIVTETEILKMIKEVDIDRNGTVEFNEFVIMMHHYTKFRSDHQGNDSEDSDIYDAFKAFDHNGDGFIDSDEIKRTMVALGESVSDSDVMAMIFEADADKDGKINFNEFKKIM 1348
            ++I +F++AF   D D DG I+ +EL      LG   TE E+  MI EVD D NGT++F EF+ MM    K        DSE+ +I +AF+ FD +G+G+I + E++  M  LGE ++D +V  MI EAD D DG++N+ EF ++M
Sbjct:    8 EQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMK------DTDSEE-EIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 146          
BLAST of Troponin C, skeletal muscle vs. Ensembl Zebrafish
Match: calm1b (calmodulin 1b [Source:ZFIN;Acc:ZDB-GENE-030804-2])

HSP 1 Score: 110.538 bits (275), Expect = 6.249e-28
Identity = 61/146 (41.78%), Postives = 90/146 (61.64%), Query Frame = 2
Query:  911 KEIQKFRDAFDSVDTDSDGRISPEELKRAFTKLGNIVTETEILKMIKEVDIDRNGTVEFNEFVIMMHHYTKFRSDHQGNDSEDSDIYDAFKAFDHNGDGFIDSDEIKRTMVALGESVSDSDVMAMIFEADADKDGKINFNEFKKIM 1348
            ++I +F++AF   D D DG I+ +EL      LG   TE E+  MI EVD D NGT++F EF+ MM    K        DSE+ +I +AF+ FD +G+G+I + E++  M  LGE ++D +V  MI EAD D DG++N+ EF ++M
Sbjct:    8 EQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMK------DTDSEE-EIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 146          
BLAST of Troponin C, skeletal muscle vs. Ensembl Xenopus
Match: CALM2 (calmodulin 1 (phosphorylase kinase, delta) [Source:NCBI gene;Acc:100496298])

HSP 1 Score: 110.538 bits (275), Expect = 8.904e-28
Identity = 61/146 (41.78%), Postives = 90/146 (61.64%), Query Frame = 2
Query:  911 KEIQKFRDAFDSVDTDSDGRISPEELKRAFTKLGNIVTETEILKMIKEVDIDRNGTVEFNEFVIMMHHYTKFRSDHQGNDSEDSDIYDAFKAFDHNGDGFIDSDEIKRTMVALGESVSDSDVMAMIFEADADKDGKINFNEFKKIM 1348
            ++I +F++AF   D D DG I+ +EL      LG   TE E+  MI EVD D NGT++F EF+ MM    K        DSE+ +I +AF+ FD +G+G+I + E++  M  LGE ++D +V  MI EAD D DG++N+ EF ++M
Sbjct:    8 EQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMK------DTDSEE-EIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 146          
BLAST of Troponin C, skeletal muscle vs. Ensembl Xenopus
Match: CALM2 (calmodulin 1 (phosphorylase kinase, delta) [Source:NCBI gene;Acc:100496298])

HSP 1 Score: 110.538 bits (275), Expect = 8.904e-28
Identity = 61/146 (41.78%), Postives = 90/146 (61.64%), Query Frame = 2
Query:  911 KEIQKFRDAFDSVDTDSDGRISPEELKRAFTKLGNIVTETEILKMIKEVDIDRNGTVEFNEFVIMMHHYTKFRSDHQGNDSEDSDIYDAFKAFDHNGDGFIDSDEIKRTMVALGESVSDSDVMAMIFEADADKDGKINFNEFKKIM 1348
            ++I +F++AF   D D DG I+ +EL      LG   TE E+  MI EVD D NGT++F EF+ MM    K        DSE+ +I +AF+ FD +G+G+I + E++  M  LGE ++D +V  MI EAD D DG++N+ EF ++M
Sbjct:    8 EQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMK------DTDSEE-EIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 146          
BLAST of Troponin C, skeletal muscle vs. Ensembl Xenopus
Match: calm2 (calmodulin 2 (phosphorylase kinase, delta) [Source:NCBI gene;Acc:493522])

HSP 1 Score: 110.538 bits (275), Expect = 8.904e-28
Identity = 61/146 (41.78%), Postives = 90/146 (61.64%), Query Frame = 2
Query:  911 KEIQKFRDAFDSVDTDSDGRISPEELKRAFTKLGNIVTETEILKMIKEVDIDRNGTVEFNEFVIMMHHYTKFRSDHQGNDSEDSDIYDAFKAFDHNGDGFIDSDEIKRTMVALGESVSDSDVMAMIFEADADKDGKINFNEFKKIM 1348
            ++I +F++AF   D D DG I+ +EL      LG   TE E+  MI EVD D NGT++F EF+ MM    K        DSE+ +I +AF+ FD +G+G+I + E++  M  LGE ++D +V  MI EAD D DG++N+ EF ++M
Sbjct:    8 EQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMK------DTDSEE-EIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 146          
BLAST of Troponin C, skeletal muscle vs. Ensembl Xenopus
Match: calm2 (calmodulin 2 (phosphorylase kinase, delta) [Source:NCBI gene;Acc:493522])

HSP 1 Score: 110.538 bits (275), Expect = 8.904e-28
Identity = 61/146 (41.78%), Postives = 90/146 (61.64%), Query Frame = 2
Query:  911 KEIQKFRDAFDSVDTDSDGRISPEELKRAFTKLGNIVTETEILKMIKEVDIDRNGTVEFNEFVIMMHHYTKFRSDHQGNDSEDSDIYDAFKAFDHNGDGFIDSDEIKRTMVALGESVSDSDVMAMIFEADADKDGKINFNEFKKIM 1348
            ++I +F++AF   D D DG I+ +EL      LG   TE E+  MI EVD D NGT++F EF+ MM    K        DSE+ +I +AF+ FD +G+G+I + E++  M  LGE ++D +V  MI EAD D DG++N+ EF ++M
Sbjct:    8 EQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMK------DTDSEE-EIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 146          
BLAST of Troponin C, skeletal muscle vs. Ensembl Xenopus
Match: CALM2 (calmodulin 1 (phosphorylase kinase, delta) [Source:NCBI gene;Acc:100496298])

HSP 1 Score: 110.153 bits (274), Expect = 9.885e-28
Identity = 61/143 (42.66%), Postives = 87/143 (60.84%), Query Frame = 2
Query:  920 QKFRDAFDSVDTDSDGRISPEELKRAFTKLGNIVTETEILKMIKEVDIDRNGTVEFNEFVIMMHHYTKFRSDHQGNDSEDSDIYDAFKAFDHNGDGFIDSDEIKRTMVALGESVSDSDVMAMIFEADADKDGKINFNEFKKIM 1348
            Q F++AF   D D DG I+ +EL      LG   TE E+  MI EVD D NGT++F EF+ MM    K        DSE+ +I +AF+ FD +G+G+I + E++  M  LGE ++D +V  MI EAD D DG++N+ EF ++M
Sbjct:    4 QTFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMK------DTDSEE-EIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 139          
BLAST of Troponin C, skeletal muscle vs. Ensembl Mouse
Match: Calm1 (calmodulin 1 [Source:MGI Symbol;Acc:MGI:88251])

HSP 1 Score: 112.849 bits (281), Expect = 3.791e-28
Identity = 61/146 (41.78%), Postives = 90/146 (61.64%), Query Frame = 2
Query:  911 KEIQKFRDAFDSVDTDSDGRISPEELKRAFTKLGNIVTETEILKMIKEVDIDRNGTVEFNEFVIMMHHYTKFRSDHQGNDSEDSDIYDAFKAFDHNGDGFIDSDEIKRTMVALGESVSDSDVMAMIFEADADKDGKINFNEFKKIM 1348
            ++I +F++AF   D D DG I+ +EL      LG   TE E+  MI EVD D NGT++F EF+ MM    K        DSE+ +I +AF+ FD +G+G+I + E++  M  LGE ++D +V  MI EAD D DG++N+ EF ++M
Sbjct:   56 EQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMK------DTDSEE-EIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 194          
BLAST of Troponin C, skeletal muscle vs. Ensembl Mouse
Match: Calm3 (calmodulin 3 [Source:MGI Symbol;Acc:MGI:103249])

HSP 1 Score: 110.538 bits (275), Expect = 6.744e-28
Identity = 61/146 (41.78%), Postives = 90/146 (61.64%), Query Frame = 2
Query:  911 KEIQKFRDAFDSVDTDSDGRISPEELKRAFTKLGNIVTETEILKMIKEVDIDRNGTVEFNEFVIMMHHYTKFRSDHQGNDSEDSDIYDAFKAFDHNGDGFIDSDEIKRTMVALGESVSDSDVMAMIFEADADKDGKINFNEFKKIM 1348
            ++I +F++AF   D D DG I+ +EL      LG   TE E+  MI EVD D NGT++F EF+ MM    K        DSE+ +I +AF+ FD +G+G+I + E++  M  LGE ++D +V  MI EAD D DG++N+ EF ++M
Sbjct:    8 EQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMK------DTDSEE-EIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 146          
BLAST of Troponin C, skeletal muscle vs. Ensembl Mouse
Match: Calm1 (calmodulin 1 [Source:MGI Symbol;Acc:MGI:88251])

HSP 1 Score: 110.538 bits (275), Expect = 6.744e-28
Identity = 61/146 (41.78%), Postives = 90/146 (61.64%), Query Frame = 2
Query:  911 KEIQKFRDAFDSVDTDSDGRISPEELKRAFTKLGNIVTETEILKMIKEVDIDRNGTVEFNEFVIMMHHYTKFRSDHQGNDSEDSDIYDAFKAFDHNGDGFIDSDEIKRTMVALGESVSDSDVMAMIFEADADKDGKINFNEFKKIM 1348
            ++I +F++AF   D D DG I+ +EL      LG   TE E+  MI EVD D NGT++F EF+ MM    K        DSE+ +I +AF+ FD +G+G+I + E++  M  LGE ++D +V  MI EAD D DG++N+ EF ++M
Sbjct:    8 EQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMK------DTDSEE-EIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 146          
BLAST of Troponin C, skeletal muscle vs. Ensembl Mouse
Match: Calm2 (calmodulin 2 [Source:MGI Symbol;Acc:MGI:103250])

HSP 1 Score: 110.538 bits (275), Expect = 6.744e-28
Identity = 61/146 (41.78%), Postives = 90/146 (61.64%), Query Frame = 2
Query:  911 KEIQKFRDAFDSVDTDSDGRISPEELKRAFTKLGNIVTETEILKMIKEVDIDRNGTVEFNEFVIMMHHYTKFRSDHQGNDSEDSDIYDAFKAFDHNGDGFIDSDEIKRTMVALGESVSDSDVMAMIFEADADKDGKINFNEFKKIM 1348
            ++I +F++AF   D D DG I+ +EL      LG   TE E+  MI EVD D NGT++F EF+ MM    K        DSE+ +I +AF+ FD +G+G+I + E++  M  LGE ++D +V  MI EAD D DG++N+ EF ++M
Sbjct:    8 EQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMK------DTDSEE-EIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 146          
BLAST of Troponin C, skeletal muscle vs. Ensembl Mouse
Match: Calml3 (calmodulin-like 3 [Source:MGI Symbol;Acc:MGI:1917655])

HSP 1 Score: 108.612 bits (270), Expect = 2.486e-27
Identity = 59/147 (40.14%), Postives = 89/147 (60.54%), Query Frame = 2
Query:  911 KEIQKFRDAFDSVDTDSDGRISPEELKRAFTKLGNIVTETEILKMIKEVDIDRNGTVEFNEFVIMMHHYTKFRSDHQGNDSEDSDIYDAFKAFDHNGDGFIDSDEIKRTMVALGESVSDSDVMAMIFEADADKDGKINFNEFKKIML 1351
            ++I +F++AF   D D DG I+ +EL      LG   TE E+  M+ E+D D NGTV+F EF+ MM    K        DSE+ +I +AF+ FD +G+GF+ + E++  M  LGE +SD +V  MI  AD D DG++N+ EF  +++
Sbjct:    8 EQIAEFKEAFSLFDKDGDGSITTQELGTVMRSLGQNPTEAELQGMVNEIDKDGNGTVDFPEFLTMMSRKMK------DTDSEE-EIREAFRVFDKDGNGFVSAAELRHVMTKLGEKLSDEEVDEMIQAADTDGDGQVNYEEFVHMLV 147          
BLAST of Troponin C, skeletal muscle vs. UniProt/SwissProt
Match: sp|Q9HFY6|CALM_BLAEM (Calmodulin OS=Blastocladiella emersonii OX=4808 GN=CMD1 PE=3 SV=3)

HSP 1 Score: 117.087 bits (292), Expect = 2.226e-29
Identity = 65/147 (44.22%), Postives = 93/147 (63.27%), Query Frame = 2
Query:  911 KEIQKFRDAFDSVDTDSDGRISPEELKRAFTKLGNIVTETEILKMIKEVDIDRNGTVEFNEFVIMMHHYTKFRSDHQGNDSEDSDIYDAFKAFDHNGDGFIDSDEIKRTMVALGESVSDSDVMAMIFEADADKDGKINFNEFKKIML 1351
            ++I +F++AF   D D DG I+ +EL      LG   TE E+L MI EVD D NGT++F EF+ MM    K       +DSE+ +I +AFK FD +G+G+I + E++  M  LGE +S+ +V  MI EAD D DG+IN+ EF K+M+
Sbjct:    8 EQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELLVMINEVDADGNGTIDFPEFLTMMARKMK------DSDSEE-EIKEAFKVFDKDGNGYISAAELRHVMTNLGEKLSEDEVEEMIREADVDGDGQINYEEFVKMMM 147          
BLAST of Troponin C, skeletal muscle vs. UniProt/SwissProt
Match: sp|Q0IUU4|CML2_ORYSJ (Putative calmodulin-like protein 2 OS=Oryza sativa subsp. japonica OX=39947 GN=CML2 PE=3 SV=2)

HSP 1 Score: 117.087 bits (292), Expect = 5.213e-29
Identity = 60/152 (39.47%), Postives = 97/152 (63.82%), Query Frame = 2
Query:  911 KEIQKFRDAFDSVDTDSDGRISPEELKRAFTKLGNIVTETEILKMIKEVDIDRNGTVEFNEFVIMMHHYTKFRSDHQGNDSEDSDIYDAFKAFDHNGDGFIDSDEIKRTMVALGESVSDSDVMAMIFEADADKDGKINFNEFKKIMLIFKQR 1366
            ++I +FR+AF+  D D DG I+ +EL      LG   TE E+ KM++EVD D +G++EF EF+ ++    K R     +   + DI +AF+ FD + +GFI  DE++  M  LG+ +SD ++  M+ EAD+D DG+IN+NEF K+M+  +++
Sbjct:    7 EQIAEFREAFNLFDKDGDGTITSKELGTVMGSLGQSPTEAELKKMVEEVDADGSGSIEFEEFLGLL--ARKLR-----DTGAEDDIREAFRVFDKDQNGFITPDELRHVMANLGDPLSDDELADMLHEADSDGDGQINYNEFLKVMMAKRRQ 151          
BLAST of Troponin C, skeletal muscle vs. UniProt/SwissProt
Match: sp|Q8X187|CALM_PAXIN (Calmodulin OS=Paxillus involutus OX=71150 GN=calA PE=2 SV=3)

HSP 1 Score: 115.931 bits (289), Expect = 5.306e-29
Identity = 66/149 (44.30%), Postives = 95/149 (63.76%), Query Frame = 2
Query:  905 NNKEIQKFRDAFDSVDTDSDGRISPEELKRAFTKLGNIVTETEILKMIKEVDIDRNGTVEFNEFVIMMHHYTKFRSDHQGNDSEDSDIYDAFKAFDHNGDGFIDSDEIKRTMVALGESVSDSDVMAMIFEADADKDGKINFNEFKKIML 1351
            + ++I +F++AF   D D DG I+ +EL      LG   TE E+  MI EVD D NGT++F EF+ MM    K R      DSE+ +I +AFK FD +G+G+I + E++  M  LGE ++D++V  MI EAD D DG+IN++EF K+ML
Sbjct:    6 SEEQISEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEGELQDMINEVDADGNGTIDFPEFLTMMAR--KMRD----TDSEE-EIKEAFKVFDKDGNGYISAAELRHVMTNLGEKLTDTEVDEMIREADVDGDGQINYDEFVKMML 147          
BLAST of Troponin C, skeletal muscle vs. UniProt/SwissProt
Match: sp|O94739|CALM_PLEOS (Calmodulin OS=Pleurotus ostreatus OX=5322 GN=CMD1 PE=2 SV=3)

HSP 1 Score: 115.546 bits (288), Expect = 7.276e-29
Identity = 66/147 (44.90%), Postives = 93/147 (63.27%), Query Frame = 2
Query:  911 KEIQKFRDAFDSVDTDSDGRISPEELKRAFTKLGNIVTETEILKMIKEVDIDRNGTVEFNEFVIMMHHYTKFRSDHQGNDSEDSDIYDAFKAFDHNGDGFIDSDEIKRTMVALGESVSDSDVMAMIFEADADKDGKINFNEFKKIML 1351
            ++I +F++AF   D D DG I+ +EL      LG   TE E+  MI EVD D NGT++F EF+ MM    K R      DSE+ +I +AFK FD +G+G+I + E++  M  LGE ++D++V  MI EAD D DG+IN+ EF K+ML
Sbjct:    8 EQISEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMAR--KMRD----TDSEE-EIKEAFKVFDKDGNGYISAAELRHVMTNLGEKLTDNEVDEMIREADVDGDGQINYEEFVKMML 147          
BLAST of Troponin C, skeletal muscle vs. UniProt/SwissProt
Match: sp|A8CEP3|CALM_SACJA (Calmodulin OS=Saccharina japonica OX=88149 GN=cam PE=2 SV=1)

HSP 1 Score: 115.546 bits (288), Expect = 8.110e-29
Identity = 65/147 (44.22%), Postives = 91/147 (61.90%), Query Frame = 2
Query:  911 KEIQKFRDAFDSVDTDSDGRISPEELKRAFTKLGNIVTETEILKMIKEVDIDRNGTVEFNEFVIMMHHYTKFRSDHQGNDSEDSDIYDAFKAFDHNGDGFIDSDEIKRTMVALGESVSDSDVMAMIFEADADKDGKINFNEFKKIML 1351
            ++I +F++AF   D D DG I+ +EL      LG   TE E+  MI EVD D NGT++F EF+ MM    K        DSE+ +I +AFK FD +G+GFI + E++  M  LGE ++D +V  MI EAD D DG+IN+ EF K+M+
Sbjct:    8 EQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELADMINEVDADGNGTIDFPEFLTMMARKMK------DTDSEE-EILEAFKVFDKDGNGFISAAELRHIMTNLGEKLTDEEVDEMIREADIDGDGQINYEEFVKMMM 147          
BLAST of Troponin C, skeletal muscle vs. TrEMBL
Match: A0A267FJ11 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig010231g1 PE=4 SV=1)

HSP 1 Score: 165.236 bits (417), Expect = 1.633e-43
Identity = 84/157 (53.50%), Postives = 110/157 (70.06%), Query Frame = 2
Query:  905 NNKEIQKFRDAFDSVDTDSDGRISPEELKRAFTKLGNIVTETEILKMIKEVDIDRNGTVEFNEFVIMMHHYTKFRSDHQGNDSEDSDIYDAFKAFDHNGDGFIDSDEIKRTMVALGESVSDSDVMAMIFEADADKDGKINFNEFKKIMLIFKQRAAQ 1375
            + ++++K +DAFD  D D+DGRIS  EL +    LG  V E E+  MI +VD + NGTVEFNEF+ MM  Y     D     SED+++++AFKAFDHNGD +ID  EIK+TM  LGE V+D+DV +MI EAD DKDG+INF EFKK++ +  QRAAQ
Sbjct:   75 SGRQLKKLKDAFDFFDIDNDGRISSVELHKVLRFLGTKVNEEEVKTMIADVDTNGNGTVEFNEFLRMMRSYYHRHCD---GHSEDAEMWEAFKAFDHNGDNYIDFTEIKKTMQFLGEEVTDADVKSMIKEADVDKDGRINFEEFKKMLSLLHQRAAQ 228          
BLAST of Troponin C, skeletal muscle vs. TrEMBL
Match: A0A267H156 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig010231g2 PE=4 SV=1)

HSP 1 Score: 165.236 bits (417), Expect = 1.835e-43
Identity = 84/157 (53.50%), Postives = 110/157 (70.06%), Query Frame = 2
Query:  905 NNKEIQKFRDAFDSVDTDSDGRISPEELKRAFTKLGNIVTETEILKMIKEVDIDRNGTVEFNEFVIMMHHYTKFRSDHQGNDSEDSDIYDAFKAFDHNGDGFIDSDEIKRTMVALGESVSDSDVMAMIFEADADKDGKINFNEFKKIMLIFKQRAAQ 1375
            + ++++K +DAFD  D D+DGRIS  EL +    LG  V E E+  MI +VD + NGTVEFNEF+ MM  Y     D     SED+++++AFKAFDHNGD +ID  EIK+TM  LGE V+D+DV +MI EAD DKDG+INF EFKK++ +  QRAAQ
Sbjct:   79 SGRQLKKLKDAFDFFDIDNDGRISSVELHKVLRFLGTKVNEEEVKTMIADVDTNGNGTVEFNEFLRMMRSYYHRHCD---GHSEDAEMWEAFKAFDHNGDNYIDFTEIKKTMQFLGEEVTDADVKSMIKEADVDKDGRINFEEFKKMLSLLHQRAAQ 232          
BLAST of Troponin C, skeletal muscle vs. TrEMBL
Match: A0A267EWH3 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig000719g1 PE=4 SV=1)

HSP 1 Score: 157.147 bits (396), Expect = 1.820e-41
Identity = 82/151 (54.30%), Postives = 107/151 (70.86%), Query Frame = 2
Query:  917 IQKFRDAFDSVDTDSDGRISPEELKRAFTKLGNIVTETEILKMIKEVDIDRNGTVEFNEFVIMMHHYTKFRSDHQGNDSEDSDIYDAFKAFDHNGDGFIDSDEIKRTMVALGESVSDSDVMAMIFEADADKDGKINFNEFKKIMLIFKQRA 1369
            ++  ++AF+  D D DGRI+  EL +    LG  VTE E+  MI +VD D NGTVEFNEF+ MM  Y  +R +   + +ED+D+++AFKAFDHNGD +ID  EIK+TM  LGE VSD DV +MI EADAD DG+INF EFKK+ML+ +QR 
Sbjct:    1 MKALKEAFNFFDIDHDGRITAGELHKVLKFLGTKVTENEVKMMIADVDSDGNGTVEFNEFLKMMKKY--YRKNAHCH-TEDADMWEAFKAFDHNGDNYIDFAEIKKTMHFLGEEVSDEDVQSMINEADADNDGRINFEEFKKMMLVMQQRG 148          
BLAST of Troponin C, skeletal muscle vs. TrEMBL
Match: A0A267E4E0 (Uncharacterized protein (Fragment) OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig000719g2 PE=4 SV=1)

HSP 1 Score: 160.614 bits (405), Expect = 1.998e-41
Identity = 82/152 (53.95%), Postives = 108/152 (71.05%), Query Frame = 2
Query:  914 EIQKFRDAFDSVDTDSDGRISPEELKRAFTKLGNIVTETEILKMIKEVDIDRNGTVEFNEFVIMMHHYTKFRSDHQGNDSEDSDIYDAFKAFDHNGDGFIDSDEIKRTMVALGESVSDSDVMAMIFEADADKDGKINFNEFKKIMLIFKQRA 1369
            +++  ++AF+  D D DGRI+  EL +    LG  VTE E+  MI +VD D NGTVEFNEF+ MM  Y  +R +   + +ED+D+++AFKAFDHNGD +ID  EIK+TM  LGE VSD DV +MI EADAD DG+INF EFKK+ML+ +QR 
Sbjct:  105 QMKALKEAFNFFDIDHDGRITAGELHKVLKFLGTKVTENEVKMMIADVDSDGNGTVEFNEFLKMMKKY--YRKNAHCH-TEDADMWEAFKAFDHNGDNYIDFAEIKKTMHFLGEEVSDEDVQSMINEADADNDGRINFEEFKKMMLVMQQRG 253          
BLAST of Troponin C, skeletal muscle vs. TrEMBL
Match: A0A1I8HZF4 (Uncharacterized protein OS=Macrostomum lignano OX=282301 PE=4 SV=1)

HSP 1 Score: 155.992 bits (393), Expect = 9.124e-41
Identity = 82/148 (55.41%), Postives = 105/148 (70.95%), Query Frame = 2
Query:  926 FRDAFDSVDTDSDGRISPEELKRAFTKLGNIVTETEILKMIKEVDIDRNGTVEFNEFVIMMHHYTKFRSDHQGNDSEDSDIYDAFKAFDHNGDGFIDSDEIKRTMVALGESVSDSDVMAMIFEADADKDGKINFNEFKKIMLIFKQRA 1369
             ++AF+  D D DGRI+  EL +    LG  VTE E+  MI +VD D NGTVEFNEF+ MM  Y  +R +   + +ED+D+++AFKAFDHNGD +ID  EIK+TM  LGE VSD DV +MI EADAD DG+INF EFKK+ML+ +QR 
Sbjct:   23 LKEAFNFFDIDHDGRITAGELHKVLKFLGTKVTENEVKMMIADVDSDGNGTVEFNEFLKMMKKY--YRKNAHCH-TEDADMWEAFKAFDHNGDNYIDFAEIKKTMHFLGEEVSDEDVQSMINEADADNDGRINFEEFKKMMLVMQQRG 167          
BLAST of Troponin C, skeletal muscle vs. Ensembl Cavefish
Match: calm3a (calmodulin [Source:NCBI gene;Acc:103037741])

HSP 1 Score: 110.538 bits (275), Expect = 5.296e-28
Identity = 61/146 (41.78%), Postives = 90/146 (61.64%), Query Frame = 2
Query:  911 KEIQKFRDAFDSVDTDSDGRISPEELKRAFTKLGNIVTETEILKMIKEVDIDRNGTVEFNEFVIMMHHYTKFRSDHQGNDSEDSDIYDAFKAFDHNGDGFIDSDEIKRTMVALGESVSDSDVMAMIFEADADKDGKINFNEFKKIM 1348
            ++I +F++AF   D D DG I+ +EL      LG   TE E+  MI EVD D NGT++F EF+ MM    K        DSE+ +I +AF+ FD +G+G+I + E++  M  LGE ++D +V  MI EAD D DG++N+ EF ++M
Sbjct:    8 EQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMK------DTDSEE-EIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 146          
BLAST of Troponin C, skeletal muscle vs. Ensembl Cavefish
Match: calm2a (calmodulin [Source:NCBI gene;Acc:103037741])

HSP 1 Score: 110.538 bits (275), Expect = 5.296e-28
Identity = 61/146 (41.78%), Postives = 90/146 (61.64%), Query Frame = 2
Query:  911 KEIQKFRDAFDSVDTDSDGRISPEELKRAFTKLGNIVTETEILKMIKEVDIDRNGTVEFNEFVIMMHHYTKFRSDHQGNDSEDSDIYDAFKAFDHNGDGFIDSDEIKRTMVALGESVSDSDVMAMIFEADADKDGKINFNEFKKIM 1348
            ++I +F++AF   D D DG I+ +EL      LG   TE E+  MI EVD D NGT++F EF+ MM    K        DSE+ +I +AF+ FD +G+G+I + E++  M  LGE ++D +V  MI EAD D DG++N+ EF ++M
Sbjct:    8 EQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMK------DTDSEE-EIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 146          
BLAST of Troponin C, skeletal muscle vs. Ensembl Cavefish
Match: calm1b (calmodulin [Source:NCBI gene;Acc:103037741])

HSP 1 Score: 110.538 bits (275), Expect = 5.296e-28
Identity = 61/146 (41.78%), Postives = 90/146 (61.64%), Query Frame = 2
Query:  911 KEIQKFRDAFDSVDTDSDGRISPEELKRAFTKLGNIVTETEILKMIKEVDIDRNGTVEFNEFVIMMHHYTKFRSDHQGNDSEDSDIYDAFKAFDHNGDGFIDSDEIKRTMVALGESVSDSDVMAMIFEADADKDGKINFNEFKKIM 1348
            ++I +F++AF   D D DG I+ +EL      LG   TE E+  MI EVD D NGT++F EF+ MM    K        DSE+ +I +AF+ FD +G+G+I + E++  M  LGE ++D +V  MI EAD D DG++N+ EF ++M
Sbjct:    8 EQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMK------DTDSEE-EIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 146          
BLAST of Troponin C, skeletal muscle vs. Ensembl Cavefish
Match: calm3a (calmodulin [Source:NCBI gene;Acc:103037741])

HSP 1 Score: 110.538 bits (275), Expect = 5.296e-28
Identity = 61/146 (41.78%), Postives = 90/146 (61.64%), Query Frame = 2
Query:  911 KEIQKFRDAFDSVDTDSDGRISPEELKRAFTKLGNIVTETEILKMIKEVDIDRNGTVEFNEFVIMMHHYTKFRSDHQGNDSEDSDIYDAFKAFDHNGDGFIDSDEIKRTMVALGESVSDSDVMAMIFEADADKDGKINFNEFKKIM 1348
            ++I +F++AF   D D DG I+ +EL      LG   TE E+  MI EVD D NGT++F EF+ MM    K        DSE+ +I +AF+ FD +G+G+I + E++  M  LGE ++D +V  MI EAD D DG++N+ EF ++M
Sbjct:    8 EQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMK------DTDSEE-EIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 146          
BLAST of Troponin C, skeletal muscle vs. Ensembl Cavefish
Match: calm3b (calmodulin 3b (phosphorylase kinase, delta) [Source:ZFIN;Acc:ZDB-GENE-030131-527])

HSP 1 Score: 107.071 bits (266), Expect = 8.565e-27
Identity = 60/144 (41.67%), Postives = 88/144 (61.11%), Query Frame = 2
Query:  917 IQKFRDAFDSVDTDSDGRISPEELKRAFTKLGNIVTETEILKMIKEVDIDRNGTVEFNEFVIMMHHYTKFRSDHQGNDSEDSDIYDAFKAFDHNGDGFIDSDEIKRTMVALGESVSDSDVMAMIFEADADKDGKINFNEFKKIM 1348
            + +F++AF   D D DG I+ +EL      LG   TE E+  MI EVD D NGT++F EF+ MM    K        DSE+ +I +AF+ FD +G+G+I + E++  M  LGE ++D +V  MI EAD D DG++N+ EF ++M
Sbjct:   10 LVEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMK------DTDSEE-EIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 146          
BLAST of Troponin C, skeletal muscle vs. Ensembl Sea Lamprey
Match: CALML3 (calmodulin like 3 [Source:HGNC Symbol;Acc:HGNC:1452])

HSP 1 Score: 110.538 bits (275), Expect = 9.181e-29
Identity = 61/146 (41.78%), Postives = 90/146 (61.64%), Query Frame = 2
Query:  911 KEIQKFRDAFDSVDTDSDGRISPEELKRAFTKLGNIVTETEILKMIKEVDIDRNGTVEFNEFVIMMHHYTKFRSDHQGNDSEDSDIYDAFKAFDHNGDGFIDSDEIKRTMVALGESVSDSDVMAMIFEADADKDGKINFNEFKKIM 1348
            ++I +F++AF   D D DG I+ +EL      LG   TE E+  MI EVD D NGT++F EF+ MM    K        DSE+ +I +AF+ FD +G+G+I + E++  M  LGE ++D +V  MI EAD D DG++N+ EF ++M
Sbjct:    8 EQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMK------DTDSEE-EIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 146          
BLAST of Troponin C, skeletal muscle vs. Ensembl Sea Lamprey
Match: CALM3 (calmodulin 3 [Source:HGNC Symbol;Acc:HGNC:1449])

HSP 1 Score: 110.538 bits (275), Expect = 1.074e-28
Identity = 61/146 (41.78%), Postives = 90/146 (61.64%), Query Frame = 2
Query:  911 KEIQKFRDAFDSVDTDSDGRISPEELKRAFTKLGNIVTETEILKMIKEVDIDRNGTVEFNEFVIMMHHYTKFRSDHQGNDSEDSDIYDAFKAFDHNGDGFIDSDEIKRTMVALGESVSDSDVMAMIFEADADKDGKINFNEFKKIM 1348
            ++I +F++AF   D D DG I+ +EL      LG   TE E+  MI EVD D NGT++F EF+ MM    K        DSE+ +I +AF+ FD +G+G+I + E++  M  LGE ++D +V  MI EAD D DG++N+ EF ++M
Sbjct:    8 EQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMK------DTDSEE-EIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 146          
BLAST of Troponin C, skeletal muscle vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006008.1 (pep scaffold:Pmarinus_7.0:GL476713:142259:146509:-1 gene:ENSPMAG00000005430.1 transcript:ENSPMAT00000006008.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 109.768 bits (273), Expect = 1.789e-28
Identity = 61/146 (41.78%), Postives = 90/146 (61.64%), Query Frame = 2
Query:  911 KEIQKFRDAFDSVDTDSDGRISPEELKRAFTKLGNIVTETEILKMIKEVDIDRNGTVEFNEFVIMMHHYTKFRSDHQGNDSEDSDIYDAFKAFDHNGDGFIDSDEIKRTMVALGESVSDSDVMAMIFEADADKDGKINFNEFKKIM 1348
            ++I +F++AF   D D DG I+ +EL      LG   TE E+  MI EVD D NGT++F EF+ MM    K        DSE+ +I +AF+ FD +G+G+I + E++  M  LGE ++D +V  MI EAD D DG++N+ EF ++M
Sbjct:    8 EQIAEFKEAFSLFDKDGDGTITVKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMK------DTDSEE-EIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 146          
BLAST of Troponin C, skeletal muscle vs. Ensembl Sea Lamprey
Match: si:rp71-17i16.4 (si:rp71-17i16.4 [Source:ZFIN;Acc:ZDB-GENE-090312-215])

HSP 1 Score: 102.834 bits (255), Expect = 9.030e-26
Identity = 56/148 (37.84%), Postives = 92/148 (62.16%), Query Frame = 2
Query:  905 NNKEIQKFRDAFDSVDTDSDGRISPEELKRAFTKLGNIVTETEILKMIKEVDIDRNGTVEFNEFVIMMHHYTKFRSDHQGNDSEDSDIYDAFKAFDHNGDGFIDSDEIKRTMVALGESVSDSDVMAMIFEADADKDGKINFNEFKKIM 1348
            N ++I +F+ AFD  D D  G IS  EL +    LG   T+ E+  +I+EVD D +GT++F EF++MM    K  S  Q     + ++ +AF+  D NGDG+ID DE+K  ++  GE+V+D ++  ++ + D + DG+++F+EF K+M
Sbjct:   18 NEEQIAEFKAAFDMFDADGGGDISTSELGKVMKLLGQTPTKEELDAIIEEVDEDGSGTIDFEEFLVMMVRQMKEESAGQ----TEEELAEAFRILDTNGDGYIDRDELKDILLNTGENVTDLEMDELMKDGDKNCDGRLDFDEFLKMM 161          
BLAST of Troponin C, skeletal muscle vs. Ensembl Sea Lamprey
Match: CETN1 (centrin 1 [Source:HGNC Symbol;Acc:HGNC:1866])

HSP 1 Score: 85.5001 bits (210), Expect = 1.517e-19
Identity = 55/153 (35.95%), Postives = 82/153 (53.59%), Query Frame = 2
Query:  890 PGIEDNNKEIQKFRDAFDSVDTDSDGRISPEELKRAFTKLGNIVTETEILKMIKEVDIDRNGTVEFNEFVIMMHHYTKFRSDHQGNDSEDSDIYDAFKAFDHNGDGFIDSDEIKRTMVALGESVSDSDVMAMIFEADADKDGKINFNEFKKIM 1348
            P  E + ++ Q+ ++AFD  D D  G I  +ELK A   LG    + EI KMI + D D +G + FN+F+ MM      +   +       +I  AF+ FD +  G I    +KR    LGE+++D ++  MI EAD D DG+IN  EF ++M
Sbjct:   32 PKPELSEEQKQEIKEAFDLFDADGSGTIDVKELKVAMRALGFEPKKEEIKKMIADFDKDGSGKINFNDFLAMMTQKMSEKDSRE-------EILKAFRLFDDDETGKISFKNLKRVAKELGETLTDEELQEMIDEADRDGDGEINEEEFLRVM 177          
BLAST of Troponin C, skeletal muscle vs. Ensembl Yeast
Match: CMD1 (Calmodulin; Ca2+ binding protein that regulates Ca2+ independent processes (mitosis, bud growth, actin organization, endocytosis, etc.) and Ca2+ dependent processes (stress-activated pathways), targets include Nuf1p, Myo2p and calcineurin; binds to the Hog1p MAPK in response to hyperosmotic stress; potentiates membrane tubulation and constriction mediated by the Rvs161p-Rvs167p complex; human CALM1 or CALM2 functionally complement repression induced inviability [Source:SGD;Acc:S000000313])

HSP 1 Score: 95.5153 bits (236), Expect = 1.239e-23
Identity = 52/146 (35.62%), Postives = 87/146 (59.59%), Query Frame = 2
Query:  911 KEIQKFRDAFDSVDTDSDGRISPEELKRAFTKLGNIVTETEILKMIKEVDIDRNGTVEFNEFVIMMHHYTKFRSDHQGNDSEDSDIYDAFKAFDHNGDGFIDSDEIKRTMVALGESVSDSDVMAMIFEADADKDGKINFNEFKKIM 1348
            ++I +F++AF   D D++G IS  EL      LG   +E E+  ++ E+D+D N  +EF+EF+ +M    K       NDSE  ++ +AFK FD NGDG I + E+K  + ++GE ++D++V  M+ E  +D  G+IN  +F  ++
Sbjct:    8 EQIAEFKEAFALFDKDNNGSISSSELATVMRSLGLSPSEAEVNDLMNEIDVDGNHQIEFSEFLALMSRQLK------SNDSE-QELLEAFKVFDKNGDGLISAAELKHVLTSIGEKLTDAEVDDMLREV-SDGSGEINIQQFAALL 145          
BLAST of Troponin C, skeletal muscle vs. Ensembl Yeast
Match: CDC31 (Calcium-binding component of the spindle pole body (SPB) half-bridge; required for SPB duplication in mitosis and meiosis II; homolog of mammalian centrin; binds multiubiquitinated proteins and is involved in proteasomal protein degradation [Source:SGD;Acc:S000005783])

HSP 1 Score: 67.781 bits (164), Expect = 7.041e-14
Identity = 50/142 (35.21%), Postives = 76/142 (53.52%), Query Frame = 2
Query:  920 QKFRDAFDSVDTDSDGRISPEELKRAFTKLGNIVTETEILKMIKEVDIDRNGTVEFNEFVIMMHHYTKFRSDHQGNDSEDSDIYDAFKAFDHNGDGFIDSDEIKRTMVALGESVSDSDVMAMIFEADADKDGKINFNEFKKI 1345
            Q+  +AF   D ++DG +   ELK A   LG  + + EIL +I E D +    +++++F I+M      R      D  D +I  AF+ FD +  G I    ++R    LGE+++D ++ AMI E D D DG+IN NEF  I
Sbjct:   23 QEIYEAFSLFDMNNDGFLDYHELKVAMKALGFELPKREILDLIDEYDSEGRHLMKYDDFYIVMGEKILKR------DPLD-EIKRAFQLFDDDHTGKISIKNLRRVAKELGETLTDEELRAMIEEFDLDGDGEINENEFIAI 157          

HSP 2 Score: 46.595 bits (109), Expect = 1.544e-6
Identity = 22/67 (32.84%), Postives = 40/67 (59.70%), Query Frame = 2
Query: 1148 DSEDSDIYDAFKAFDHNGDGFIDSDEIKRTMVALGESVSDSDVMAMIFEADADKDGKINFNEFKKIM 1348
            + +  +IY+AF  FD N DGF+D  E+K  M ALG  +   +++ +I E D++    + +++F  +M
Sbjct:   19 EEQKQEIYEAFSLFDMNNDGFLDYHELKVAMKALGFELPKREILDLIDEYDSEGRHLMKYDDFYIVM 85          

HSP 3 Score: 45.0542 bits (105), Expect = 5.009e-6
Identity = 22/61 (36.07%), Postives = 37/61 (60.66%), Query Frame = 2
Query:  917 IQKFRDAFDSVDTDSDGRISPEELKRAFTKLGNIVTETEILKMIKEVDIDRNGTVEFNEFV 1099
            + + + AF   D D  G+IS + L+R   +LG  +T+ E+  MI+E D+D +G +  NEF+
Sbjct:   95 LDEIKRAFQLFDDDHTGKISIKNLRRVAKELGETLTDEELRAMIEEFDLDGDGEINENEFI 155          
BLAST of Troponin C, skeletal muscle vs. Ensembl Yeast
Match: CNB1 (Calcineurin B; regulatory subunit of calcineurin, a Ca++/calmodulin-regulated type 2B protein phosphatase which regulates Crz1p (stress-response transcription factor); other calcineurin subunit encoded by CNA1 and/or CMP1; regulates function of Aly1p alpha-arrestin; myristoylation by Nmt1p reduces calcineurin activity in response to submaximal Ca signals, is needed to prevent constitutive phosphatase activity; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000001673])

HSP 1 Score: 57.3806 bits (137), Expect = 4.368e-10
Identity = 45/163 (27.61%), Postives = 83/163 (50.92%), Query Frame = 2
Query:  875 ANVIEPGIEDNN---KEIQKFRDAFDSVDTDSDGRISPEELKRAFTKLGNIVTETEILKMIKEVDIDRNGTVEFNEFVIMMHHYTKFRSDHQGNDSEDSDIYDAFKAFDHNGDGFIDSDEIKRTM-VALGESVSDSDVMAM----IFEADADKDGKINFNEFK 1339
            + +++  +ED N    EI++ R  F  +D DS G I   E    F  +  + +     ++++  D D +G V+F EF+  +  ++       G  S+D  +  AFK +D + DGFI + E+   + + +G ++ D  +  +    I E D+D DG+++F EFK
Sbjct:    6 SKIVDGLLEDTNFDRDEIERLRKRFMKLDRDSSGSIDKNE----FMSIPGVSSNPLAGRIMEVFDADNSGDVDFQEFITGLSIFS-------GRGSKDEKLRFAFKIYDIDKDGFISNGELFIVLKIMVGSNLDDEQLQQIVDRTIVENDSDGDGRLSFEEFK 157          
BLAST of Troponin C, skeletal muscle vs. Ensembl Nematostella
Match: EDO46518 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RPI8])

HSP 1 Score: 112.464 bits (280), Expect = 3.568e-29
Identity = 63/146 (43.15%), Postives = 90/146 (61.64%), Query Frame = 2
Query:  911 KEIQKFRDAFDSVDTDSDGRISPEELKRAFTKLGNIVTETEILKMIKEVDIDRNGTVEFNEFVIMMHHYTKFRSDHQGNDSEDSDIYDAFKAFDHNGDGFIDSDEIKRTMVALGESVSDSDVMAMIFEADADKDGKINFNEFKKIM 1348
            ++I +F++AF   D D DG I+ +EL      LG   TE E+  MI EVD D NGT++F EF+ MM    K        DSE+ +I +AF+ FD +G+GFI + E++  M  LGE ++D +V  MI EAD D DG++N+ EF K+M
Sbjct:    8 EQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMK------DTDSEE-EIREAFRVFDKDGNGFISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVKMM 146          
BLAST of Troponin C, skeletal muscle vs. Ensembl Nematostella
Match: EDO46606 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RPN8])

HSP 1 Score: 111.309 bits (277), Expect = 6.420e-29
Identity = 60/144 (41.67%), Postives = 87/144 (60.42%), Query Frame = 2
Query:  917 IQKFRDAFDSVDTDSDGRISPEELKRAFTKLGNIVTETEILKMIKEVDIDRNGTVEFNEFVIMMHHYTKFRSDHQGNDSEDSDIYDAFKAFDHNGDGFIDSDEIKRTMVALGESVSDSDVMAMIFEADADKDGKINFNEFKKIM 1348
            + +F++AF   D D DG I+ +EL      LG   TE E+  MI EVD D NGT++F EF+ MM    K       N   + +I +AF+ FD +G+GFI + E++  M  LGE ++D +V  MI EAD D DG++N++EF K+M
Sbjct:    1 MTEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMK-------NTDSEEEIREAFRVFDKDGNGFISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYDEFVKMM 137          
BLAST of Troponin C, skeletal muscle vs. Ensembl Nematostella
Match: EDO30674 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T043])

HSP 1 Score: 106.301 bits (264), Expect = 1.124e-26
Identity = 58/142 (40.85%), Postives = 86/142 (60.56%), Query Frame = 2
Query:  923 KFRDAFDSVDTDSDGRISPEELKRAFTKLGNIVTETEILKMIKEVDIDRNGTVEFNEFVIMMHHYTKFRSDHQGNDSEDSDIYDAFKAFDHNGDGFIDSDEIKRTMVALGESVSDSDVMAMIFEADADKDGKINFNEFKKIM 1348
            + ++AF   D D  G IS EEL+     LG   ++ E+ +MI+EVD D NG V+F EF+ MM    + R      D+E +++ +AF+ FD NGDG I   E++  M +LGE +SD ++  M+ EAD D DG INF EF +++
Sbjct:   20 ELQEAFSLFDKDGSGTISNEELEVVMKSLGQNPSDEELQQMIQEVDADGNGEVDFEEFLAMMKKQMQHR------DAE-AEMREAFRVFDRNGDGSISEWELRSVMASLGEKLSDDEIKEMMREADLDGDGVINFQEFVQMV 154          

HSP 2 Score: 52.7582 bits (125), Expect = 3.951e-8
Identity = 25/67 (37.31%), Postives = 39/67 (58.21%), Query Frame = 2
Query:  923 KFRDAFDSVDTDSDGRISPEELKRAFTKLGNIVTETEILKMIKEVDIDRNGTVEFNEFVIMMHHYTK 1123
            + R+AF   D + DG IS  EL+     LG  +++ EI +M++E D+D +G + F EFV M+    K
Sbjct:   93 EMREAFRVFDRNGDGSISEWELRSVMASLGEKLSDDEIKEMMREADLDGDGVINFQEFVQMVREMDK 159          
BLAST of Troponin C, skeletal muscle vs. Ensembl Nematostella
Match: EDO33580 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SRU7])

HSP 1 Score: 99.3673 bits (246), Expect = 1.746e-24
Identity = 59/149 (39.60%), Postives = 88/149 (59.06%), Query Frame = 2
Query:  905 NNKEIQKFRDAFDSVDTDSDGRISPEELKRAFTKLGNIVTETEILKMIKEVDIDRNGTVEFNEFVIMMHHYTKFRSDHQGNDSEDSDIYDAFKAFDHNGDGFIDSDEIKRTMVALGESVSDSDVMAMIFEADADKDGKINFNEFKKIML 1351
              +EI ++++AF   D D DG ++  EL      LG   T+ EI +MIKEVD D +G++ F EF+ +M   TK      G   ED ++  AF+ FD +G+G I   E+K  + +LGE +S+ +V  MI EAD+D DG +N  EF K+M+
Sbjct:    6 TEEEIAEYKEAFSLFDKDGDGTVTTAELGTVMRNLGQNPTDEEIREMIKEVDEDGSGSIGFEEFLQLMSKKTK------GKSYED-ELMAAFQIFDKDGNGSITVTELKEVLDSLGEKLSEDEVGEMIKEADSDGDGTVNIEEFIKMMV 147          
BLAST of Troponin C, skeletal muscle vs. Ensembl Nematostella
Match: EDO45935 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RRE8])

HSP 1 Score: 97.8265 bits (242), Expect = 5.178e-24
Identity = 58/150 (38.67%), Postives = 88/150 (58.67%), Query Frame = 2
Query:  911 KEIQKFRDAFDSVDTDSDGRISPEELKRAFTKLGNIVTETEILKMIKEVDIDRNGTVEFNEFVIMMHHYTKFRSDHQGNDSEDSDIYDAFKAFDHNGDGFIDSDEIKRTMVALGESVSD----SDVMAMIFEADADKDGKINFNEFKKIM 1348
            +++ +   AF   DT+ DG+IS EEL +A  + G +V++ E+  MI+ VD+D NG VEF EFV MM       ++  G  +   ++   F  FD +G+GFIDSDE+K  + A   +++       V AMI  AD + DGKI+F EF K++
Sbjct:    8 EQLSEIEAAFKMYDTNGDGQISAEELGQAMREAGQLVSDEELKDMIRAVDLDGNGKVEFKEFVQMM-------ANQLGQPAPVEEMKAYFDRFDQDGNGFIDSDEMKCLVRAFYSNLTGDALKQQVRAMIEAADTNSDGKISFEEFVKVL 150          
BLAST of Troponin C, skeletal muscle vs. Ensembl Medaka
Match: calm2a (calmodulin 2 [Source:NCBI gene;Acc:100049420])

HSP 1 Score: 110.538 bits (275), Expect = 5.263e-28
Identity = 61/146 (41.78%), Postives = 90/146 (61.64%), Query Frame = 2
Query:  911 KEIQKFRDAFDSVDTDSDGRISPEELKRAFTKLGNIVTETEILKMIKEVDIDRNGTVEFNEFVIMMHHYTKFRSDHQGNDSEDSDIYDAFKAFDHNGDGFIDSDEIKRTMVALGESVSDSDVMAMIFEADADKDGKINFNEFKKIM 1348
            ++I +F++AF   D D DG I+ +EL      LG   TE E+  MI EVD D NGT++F EF+ MM    K        DSE+ +I +AF+ FD +G+G+I + E++  M  LGE ++D +V  MI EAD D DG++N+ EF ++M
Sbjct:    8 EQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMK------DTDSEE-EIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 146          
BLAST of Troponin C, skeletal muscle vs. Ensembl Medaka
Match: ENSORLT00000008599.2 (calmodulin 3 [Source:NCBI gene;Acc:100049421])

HSP 1 Score: 110.538 bits (275), Expect = 5.263e-28
Identity = 61/146 (41.78%), Postives = 90/146 (61.64%), Query Frame = 2
Query:  911 KEIQKFRDAFDSVDTDSDGRISPEELKRAFTKLGNIVTETEILKMIKEVDIDRNGTVEFNEFVIMMHHYTKFRSDHQGNDSEDSDIYDAFKAFDHNGDGFIDSDEIKRTMVALGESVSDSDVMAMIFEADADKDGKINFNEFKKIM 1348
            ++I +F++AF   D D DG I+ +EL      LG   TE E+  MI EVD D NGT++F EF+ MM    K        DSE+ +I +AF+ FD +G+G+I + E++  M  LGE ++D +V  MI EAD D DG++N+ EF ++M
Sbjct:    8 EQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMK------DTDSEE-EIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 146          
BLAST of Troponin C, skeletal muscle vs. Ensembl Medaka
Match: calm1b (calmodulin [Source:NCBI gene;Acc:100049419])

HSP 1 Score: 110.538 bits (275), Expect = 5.263e-28
Identity = 61/146 (41.78%), Postives = 90/146 (61.64%), Query Frame = 2
Query:  911 KEIQKFRDAFDSVDTDSDGRISPEELKRAFTKLGNIVTETEILKMIKEVDIDRNGTVEFNEFVIMMHHYTKFRSDHQGNDSEDSDIYDAFKAFDHNGDGFIDSDEIKRTMVALGESVSDSDVMAMIFEADADKDGKINFNEFKKIM 1348
            ++I +F++AF   D D DG I+ +EL      LG   TE E+  MI EVD D NGT++F EF+ MM    K        DSE+ +I +AF+ FD +G+G+I + E++  M  LGE ++D +V  MI EAD D DG++N+ EF ++M
Sbjct:    8 EQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMK------DTDSEE-EIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 146          
BLAST of Troponin C, skeletal muscle vs. Ensembl Medaka
Match: ENSORLT00000022188.2 (calmodulin [Source:NCBI gene;Acc:100049422])

HSP 1 Score: 108.997 bits (271), Expect = 2.119e-27
Identity = 61/146 (41.78%), Postives = 90/146 (61.64%), Query Frame = 2
Query:  911 KEIQKFRDAFDSVDTDSDGRISPEELKRAFTKLGNIVTETEILKMIKEVDIDRNGTVEFNEFVIMMHHYTKFRSDHQGNDSEDSDIYDAFKAFDHNGDGFIDSDEIKRTMVALGESVSDSDVMAMIFEADADKDGKINFNEFKKIM 1348
            ++I +F++AF   D D DG I+ +EL      LG   TE E+  MI EVD D NGT++F EF+ MM    K        DSE+ +I +AF+ FD +G+G+I + E++  M  LGE ++D +V  MI EAD D DG++N+ EF ++M
Sbjct:   22 EQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMK------DTDSEE-EIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 160          

HSP 2 Score: 50.447 bits (119), Expect = 6.478e-7
Identity = 29/85 (34.12%), Postives = 52/85 (61.18%), Query Frame = 2
Query: 1094 FVIMMHHYTKFRSDHQGNDSEDSDIYDAFKAFDHNGDGFIDSDEIKRTMVALGESVSDSDVMAMIFEADADKDGKINFNEFKKIM 1348
            F+ + H    F++D Q  + + ++  +AF  FD +GDG I + E+   M +LG++ +++++  MI E DAD +G I+F EF  +M
Sbjct:    8 FLFVFH----FKAD-QLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMM 87          
BLAST of Troponin C, skeletal muscle vs. Ensembl Medaka
Match: si:rp71-17i16.4 (troponin C, skeletal muscle [Source:NCBI gene;Acc:101171577])

HSP 1 Score: 103.605 bits (257), Expect = 8.537e-25
Identity = 57/144 (39.58%), Postives = 88/144 (61.11%), Query Frame = 2
Query:  917 IQKFRDAFDSVDTDSDGRISPEELKRAFTKLGNIVTETEILKMIKEVDIDRNGTVEFNEFVIMMHHYTKFRSDHQGNDSEDSDIYDAFKAFDHNGDGFIDSDEIKRTMVALGESVSDSDVMAMIFEADADKDGKINFNEFKKIM 1348
            I +F+ AFD  DTD  G IS +EL      LG   +  E+  +I+EVD D +GT++F EF++MM    + + D  G   E+  + + F+ FD N DGF+D +E    +   GE+V++ D+  M  EAD++KDGK++F+EF K+M
Sbjct:   82 ITEFKAAFDMFDTDGGGDISTKELGTVMRMLGQNPSREELDAIIEEVDEDGSGTIDFEEFLVMMVQ--QLKEDQAGKSEEE--LSECFRIFDKNSDGFVDREEFGDILHMTGEAVTEEDIDEMFGEADSNKDGKLDFDEFLKMM 221          
BLAST of Troponin C, skeletal muscle vs. Planmine SMEST
Match: SMESG000005066.1 (SMESG000005066.1)

HSP 1 Score: 638.262 bits (1645), Expect = 0.000e+0
Identity = 368/369 (99.73%), Postives = 368/369 (99.73%), Query Frame = 2
Query:  272 MMSRKNRPVREQELQKLTESYGXXXXXXXXXXXXXXXXXXXXXXXXTDSQMSDFHDNDCRVEINNVNSGLVNKIDNKCNDVKDESFIPKSSLFVNKSPSPSFXXXXXXXXXXXXXXXXXXXXXXRVNSLTKRNIRLPDCIVKSNFCPSALRNQPIRNSIPQDSNSPGKQRKHKINITSPNLADSKFPTCSTPIRKYKENQNANVIEPGIEDNNKEIQKFRDAFDSVDTDSDGRISPEELKRAFTKLGNIVTETEILKMIKEVDIDRNGTVEFNEFVIMMHHYTKFRSDHQGNDSEDSDIYDAFKAFDHNGDGFIDSDEIKRTMVALGESVSDSDVMAMIFEADADKDGKINFNEFKKIMLIFKQRAAQK 1378
            MMSRKNRPVREQELQKLTESYGEVSDDDEFDFPEFDASSSYSYYSSTDSQMSDFHDNDCRVEINNVNSGLVNKIDNKCNDVKDESFIPKSSLFVNKSPSPSFKSQNCSKNCSESSKSVEKSETSRVNSLTKRNIRLPDCIVKSNFCPSALRNQPIRNSIPQDSNSPGKQRKHKINITSPNLADSKFPTCSTPIRKYKENQNANV EPGIEDNNKEIQKFRDAFDSVDTDSDGRISPEELKRAFTKLGNIVTETEILKMIKEVDIDRNGTVEFNEFVIMMHHYTKFRSDHQGNDSEDSDIYDAFKAFDHNGDGFIDSDEIKRTMVALGESVSDSDVMAMIFEADADKDGKINFNEFKKIMLIFKQRAAQK
Sbjct:    1 MMSRKNRPVREQELQKLTESYGEVSDDDEFDFPEFDASSSYSYYSSTDSQMSDFHDNDCRVEINNVNSGLVNKIDNKCNDVKDESFIPKSSLFVNKSPSPSFKSQNCSKNCSESSKSVEKSETSRVNSLTKRNIRLPDCIVKSNFCPSALRNQPIRNSIPQDSNSPGKQRKHKINITSPNLADSKFPTCSTPIRKYKENQNANVKEPGIEDNNKEIQKFRDAFDSVDTDSDGRISPEELKRAFTKLGNIVTETEILKMIKEVDIDRNGTVEFNEFVIMMHHYTKFRSDHQGNDSEDSDIYDAFKAFDHNGDGFIDSDEIKRTMVALGESVSDSDVMAMIFEADADKDGKINFNEFKKIMLIFKQRAAQK 369          
BLAST of Troponin C, skeletal muscle vs. Planmine SMEST
Match: SMESG000005066.1 (SMESG000005066.1)

HSP 1 Score: 635.95 bits (1639), Expect = 0.000e+0
Identity = 367/368 (99.73%), Postives = 367/368 (99.73%), Query Frame = 2
Query:  275 MSRKNRPVREQELQKLTESYGXXXXXXXXXXXXXXXXXXXXXXXXTDSQMSDFHDNDCRVEINNVNSGLVNKIDNKCNDVKDESFIPKSSLFVNKSPSPSFXXXXXXXXXXXXXXXXXXXXXXRVNSLTKRNIRLPDCIVKSNFCPSALRNQPIRNSIPQDSNSPGKQRKHKINITSPNLADSKFPTCSTPIRKYKENQNANVIEPGIEDNNKEIQKFRDAFDSVDTDSDGRISPEELKRAFTKLGNIVTETEILKMIKEVDIDRNGTVEFNEFVIMMHHYTKFRSDHQGNDSEDSDIYDAFKAFDHNGDGFIDSDEIKRTMVALGESVSDSDVMAMIFEADADKDGKINFNEFKKIMLIFKQRAAQK 1378
            MSRKNRPVREQELQKLTESYGEVSDDDEFDFPEFDASSSYSYYSSTDSQMSDFHDNDCRVEINNVNSGLVNKIDNKCNDVKDESFIPKSSLFVNKSPSPSFKSQNCSKNCSESSKSVEKSETSRVNSLTKRNIRLPDCIVKSNFCPSALRNQPIRNSIPQDSNSPGKQRKHKINITSPNLADSKFPTCSTPIRKYKENQNANV EPGIEDNNKEIQKFRDAFDSVDTDSDGRISPEELKRAFTKLGNIVTETEILKMIKEVDIDRNGTVEFNEFVIMMHHYTKFRSDHQGNDSEDSDIYDAFKAFDHNGDGFIDSDEIKRTMVALGESVSDSDVMAMIFEADADKDGKINFNEFKKIMLIFKQRAAQK
Sbjct:    1 MSRKNRPVREQELQKLTESYGEVSDDDEFDFPEFDASSSYSYYSSTDSQMSDFHDNDCRVEINNVNSGLVNKIDNKCNDVKDESFIPKSSLFVNKSPSPSFKSQNCSKNCSESSKSVEKSETSRVNSLTKRNIRLPDCIVKSNFCPSALRNQPIRNSIPQDSNSPGKQRKHKINITSPNLADSKFPTCSTPIRKYKENQNANVKEPGIEDNNKEIQKFRDAFDSVDTDSDGRISPEELKRAFTKLGNIVTETEILKMIKEVDIDRNGTVEFNEFVIMMHHYTKFRSDHQGNDSEDSDIYDAFKAFDHNGDGFIDSDEIKRTMVALGESVSDSDVMAMIFEADADKDGKINFNEFKKIMLIFKQRAAQK 368          
BLAST of Troponin C, skeletal muscle vs. Planmine SMEST
Match: SMESG000005066.1 (SMESG000005066.1)

HSP 1 Score: 526.939 bits (1356), Expect = 0.000e+0
Identity = 284/285 (99.65%), Postives = 284/285 (99.65%), Query Frame = 2
Query:  524 SFIPKSSLFVNKSPSPSFXXXXXXXXXXXXXXXXXXXXXXRVNSLTKRNIRLPDCIVKSNFCPSALRNQPIRNSIPQDSNSPGKQRKHKINITSPNLADSKFPTCSTPIRKYKENQNANVIEPGIEDNNKEIQKFRDAFDSVDTDSDGRISPEELKRAFTKLGNIVTETEILKMIKEVDIDRNGTVEFNEFVIMMHHYTKFRSDHQGNDSEDSDIYDAFKAFDHNGDGFIDSDEIKRTMVALGESVSDSDVMAMIFEADADKDGKINFNEFKKIMLIFKQRAAQK 1378
            SFIPKSSLFVNKSPSPSFKSQNCSKNCSESSKSVEKSETSRVNSLTKRNIRLPDCIVKSNFCPSALRNQPIRNSIPQDSNSPGKQRKHKINITSPNLADSKFPTCSTPIRKYKENQNANV EPGIEDNNKEIQKFRDAFDSVDTDSDGRISPEELKRAFTKLGNIVTETEILKMIKEVDIDRNGTVEFNEFVIMMHHYTKFRSDHQGNDSEDSDIYDAFKAFDHNGDGFIDSDEIKRTMVALGESVSDSDVMAMIFEADADKDGKINFNEFKKIMLIFKQRAAQK
Sbjct:    2 SFIPKSSLFVNKSPSPSFKSQNCSKNCSESSKSVEKSETSRVNSLTKRNIRLPDCIVKSNFCPSALRNQPIRNSIPQDSNSPGKQRKHKINITSPNLADSKFPTCSTPIRKYKENQNANVKEPGIEDNNKEIQKFRDAFDSVDTDSDGRISPEELKRAFTKLGNIVTETEILKMIKEVDIDRNGTVEFNEFVIMMHHYTKFRSDHQGNDSEDSDIYDAFKAFDHNGDGFIDSDEIKRTMVALGESVSDSDVMAMIFEADADKDGKINFNEFKKIMLIFKQRAAQK 286          
BLAST of Troponin C, skeletal muscle vs. Planmine SMEST
Match: SMESG000075370.1 (SMESG000075370.1)

HSP 1 Score: 159.458 bits (402), Expect = 4.390e-45
Identity = 82/157 (52.23%), Postives = 117/157 (74.52%), Query Frame = 2
Query:  905 NNKEIQKFRDAFDSVDTDSDGRISPEELKRAFTKLGNIVTETEILKMIKEVDIDRNGTVEFNEFVIMMHHYTKFRSDH-QGNDSEDSDIYDAFKAFDHNGDGFIDSDEIKRTMVALGESVSDSDVMAMIFEADADKDGKINFNEFKKIMLIFKQRAA 1372
            +N+  + +RDAF+SVD + DGRI+  ELK AF KLG+ VT+ ++ KMI+  D+D NGTVE+ EFV +M    +FRS   +   S D++ Y+ FKAFDHNGD  +D +EIK TM+ALGE V+D +V AMI EAD D++GKI+F+EFK+IM +F++++A
Sbjct:   56 HNRNDRDYRDAFNSVDANFDGRITMIELKEAFEKLGHTVTDEDVQKMIQGADLDNNGTVEYEEFVELM---KRFRSTKPKKVKSTDTEAYEVFKAFDHNGDDLLDFNEIKSTMIALGERVTDDEVRAMIIEADLDRNGKIDFSEFKRIMEMFQKKSA 209          

HSP 2 Score: 51.6026 bits (122), Expect = 3.608e-7
Identity = 29/74 (39.19%), Postives = 40/74 (54.05%), Query Frame = 2
Query: 1157 DSDIYDAFKAFDHNGDGFIDSDEIKRTMVALGESVSDSDVMAMIFEADADKDGKINFNEFKKIMLIFKQRAAQK 1378
            D D  DAF + D N DG I   E+K     LG +V+D DV  MI  AD D +G + + EF ++M  F+    +K
Sbjct:   60 DRDYRDAFNSVDANFDGRITMIELKEAFEKLGHTVTDEDVQKMIQGADLDNNGTVEYEEFVELMKRFRSTKPKK 133          
BLAST of Troponin C, skeletal muscle vs. Planmine SMEST
Match: SMESG000034095.1 (SMESG000034095.1)

HSP 1 Score: 110.538 bits (275), Expect = 3.702e-28
Identity = 62/146 (42.47%), Postives = 89/146 (60.96%), Query Frame = 2
Query:  911 KEIQKFRDAFDSVDTDSDGRISPEELKRAFTKLGNIVTETEILKMIKEVDIDRNGTVEFNEFVIMMHHYTKFRSDHQGNDSEDSDIYDAFKAFDHNGDGFIDSDEIKRTMVALGESVSDSDVMAMIFEADADKDGKINFNEFKKIM 1348
            ++I +F++AF   D D DG I+ +EL      LG   TE E+  MI EVD D NGT++F EF+ MM    K        DSE+ +I +AF+ FD +G+GFI + E++  M  LGE ++D +V  MI EAD D DG++N+ EF  +M
Sbjct:    8 EQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMK------DTDSEE-EIREAFRVFDKDGNGFISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVTMM 146          
The following BLAST results are available for this feature:
BLAST of Troponin C, skeletal muscle vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
CALM29.823e-2841.78calmodulin 2 [Source:HGNC Symbol;Acc:HGNC:1445][more]
CALM29.823e-2841.78calmodulin 2 [Source:HGNC Symbol;Acc:HGNC:1445][more]
CALM19.823e-2841.78calmodulin 1 [Source:HGNC Symbol;Acc:HGNC:1442][more]
CALM39.823e-2841.78calmodulin 3 [Source:HGNC Symbol;Acc:HGNC:1449][more]
CALM39.823e-2841.78calmodulin 3 [Source:HGNC Symbol;Acc:HGNC:1449][more]
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BLAST of Troponin C, skeletal muscle vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
cmd-13.531e-2842.47Calmodulin [Source:UniProtKB/Swiss-Prot;Acc:O1630... [more]
cal-11.372e-2743.15Calmodulin-like protein [Source:UniProtKB/Swiss-P... [more]
cal-12.398e-2743.15Calmodulin-like protein [Source:UniProtKB/Swiss-P... [more]
cal-24.668e-2643.06CALmodulin related genes; Calmodulin-like protein ... [more]
cmd-11.516e-2144.74Calmodulin [Source:UniProtKB/Swiss-Prot;Acc:O1630... [more]
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BLAST of Troponin C, skeletal muscle vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Cam4.224e-2842.47gene:FBgn0000253 transcript:FBtr0304964[more]
Cam4.224e-2842.47gene:FBgn0000253 transcript:FBtr0088001[more]
Cam4.224e-2842.47gene:FBgn0000253 transcript:FBtr0304963[more]
Cam4.224e-2842.47gene:FBgn0000253 transcript:FBtr0088002[more]
Cam4.224e-2842.47gene:FBgn0000253 transcript:FBtr0345018[more]
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BLAST of Troponin C, skeletal muscle vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
calm2a5.341e-2841.78calmodulin 2a (phosphorylase kinase, delta) [Sourc... [more]
calm3a6.249e-2841.78calmodulin 3a (phosphorylase kinase, delta) [Sourc... [more]
calm3b6.249e-2841.78calmodulin 3b (phosphorylase kinase, delta) [Sourc... [more]
calm1b6.249e-2841.78calmodulin 1b [Source:ZFIN;Acc:ZDB-GENE-030804-2][more]
calm1b6.249e-2841.78calmodulin 1b [Source:ZFIN;Acc:ZDB-GENE-030804-2][more]
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BLAST of Troponin C, skeletal muscle vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
CALM28.904e-2841.78calmodulin 1 (phosphorylase kinase, delta) [Source... [more]
CALM28.904e-2841.78calmodulin 1 (phosphorylase kinase, delta) [Source... [more]
calm28.904e-2841.78calmodulin 2 (phosphorylase kinase, delta) [Source... [more]
calm28.904e-2841.78calmodulin 2 (phosphorylase kinase, delta) [Source... [more]
CALM29.885e-2842.66calmodulin 1 (phosphorylase kinase, delta) [Source... [more]
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BLAST of Troponin C, skeletal muscle vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Calm13.791e-2841.78calmodulin 1 [Source:MGI Symbol;Acc:MGI:88251][more]
Calm36.744e-2841.78calmodulin 3 [Source:MGI Symbol;Acc:MGI:103249][more]
Calm16.744e-2841.78calmodulin 1 [Source:MGI Symbol;Acc:MGI:88251][more]
Calm26.744e-2841.78calmodulin 2 [Source:MGI Symbol;Acc:MGI:103250][more]
Calml32.486e-2740.14calmodulin-like 3 [Source:MGI Symbol;Acc:MGI:19176... [more]
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BLAST of Troponin C, skeletal muscle vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q9HFY6|CALM_BLAEM2.226e-2944.22Calmodulin OS=Blastocladiella emersonii OX=4808 GN... [more]
sp|Q0IUU4|CML2_ORYSJ5.213e-2939.47Putative calmodulin-like protein 2 OS=Oryza sativa... [more]
sp|Q8X187|CALM_PAXIN5.306e-2944.30Calmodulin OS=Paxillus involutus OX=71150 GN=calA ... [more]
sp|O94739|CALM_PLEOS7.276e-2944.90Calmodulin OS=Pleurotus ostreatus OX=5322 GN=CMD1 ... [more]
sp|A8CEP3|CALM_SACJA8.110e-2944.22Calmodulin OS=Saccharina japonica OX=88149 GN=cam ... [more]
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BLAST of Troponin C, skeletal muscle vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A267FJ111.633e-4353.50Uncharacterized protein OS=Macrostomum lignano OX=... [more]
A0A267H1561.835e-4353.50Uncharacterized protein OS=Macrostomum lignano OX=... [more]
A0A267EWH31.820e-4154.30Uncharacterized protein OS=Macrostomum lignano OX=... [more]
A0A267E4E01.998e-4153.95Uncharacterized protein (Fragment) OS=Macrostomum ... [more]
A0A1I8HZF49.124e-4155.41Uncharacterized protein OS=Macrostomum lignano OX=... [more]
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BLAST of Troponin C, skeletal muscle vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
calm3a5.296e-2841.78calmodulin [Source:NCBI gene;Acc:103037741][more]
calm2a5.296e-2841.78calmodulin [Source:NCBI gene;Acc:103037741][more]
calm1b5.296e-2841.78calmodulin [Source:NCBI gene;Acc:103037741][more]
calm3a5.296e-2841.78calmodulin [Source:NCBI gene;Acc:103037741][more]
calm3b8.565e-2741.67calmodulin 3b (phosphorylase kinase, delta) [Sourc... [more]
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BLAST of Troponin C, skeletal muscle vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
CALML39.181e-2941.78calmodulin like 3 [Source:HGNC Symbol;Acc:HGNC:145... [more]
CALM31.074e-2841.78calmodulin 3 [Source:HGNC Symbol;Acc:HGNC:1449][more]
ENSPMAT00000006008.11.789e-2841.78pep scaffold:Pmarinus_7.0:GL476713:142259:146509:-... [more]
si:rp71-17i16.49.030e-2637.84si:rp71-17i16.4 [Source:ZFIN;Acc:ZDB-GENE-090312-2... [more]
CETN11.517e-1935.95centrin 1 [Source:HGNC Symbol;Acc:HGNC:1866][more]
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BLAST of Troponin C, skeletal muscle vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 3
Match NameE-valueIdentityDescription
CMD11.239e-2335.62Calmodulin; Ca2+ binding protein that regulates Ca... [more]
CDC317.041e-1435.21Calcium-binding component of the spindle pole body... [more]
CNB14.368e-1027.61Calcineurin B; regulatory subunit of calcineurin, ... [more]
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BLAST of Troponin C, skeletal muscle vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO465183.568e-2943.15Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO466066.420e-2941.67Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO306741.124e-2640.85Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO335801.746e-2439.60Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO459355.178e-2438.67Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Troponin C, skeletal muscle vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
calm2a5.263e-2841.78calmodulin 2 [Source:NCBI gene;Acc:100049420][more]
ENSORLT00000008599.25.263e-2841.78calmodulin 3 [Source:NCBI gene;Acc:100049421][more]
calm1b5.263e-2841.78calmodulin [Source:NCBI gene;Acc:100049419][more]
ENSORLT00000022188.22.119e-2741.78calmodulin [Source:NCBI gene;Acc:100049422][more]
si:rp71-17i16.48.537e-2539.58troponin C, skeletal muscle [Source:NCBI gene;Acc:... [more]
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BLAST of Troponin C, skeletal muscle vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000005066.10.000e+099.73SMESG000005066.1[more]
SMESG000005066.10.000e+099.73SMESG000005066.1[more]
SMESG000005066.10.000e+099.65SMESG000005066.1[more]
SMESG000075370.14.390e-4552.23SMESG000075370.1[more]
SMESG000034095.13.702e-2842.47SMESG000034095.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30018233 ID=SMED30018233|Name=Troponin C, skeletal muscle|organism=Schmidtea mediterranea sexual|type=transcript|length=1799bp
CAACCATTAGCGTAGATTGCTGAATTTGAAATCACACTCATCCAGTACTC
TCCGATTCAAGTGTATCTCCAAAAATAAGTGGTTTTATTATTTTTTTTCT
ATTGTATTCTTTGTGACATAAAACCGTTGATGATATTTGCATTGGGATTT
ATTCATTTGACTTGGGTTTAAATGACGATTTCATTGTGACTTGCAGAGAT
ATTTTATATGAATTGAATGAAGAAATTCGGTTGGCATCTATTAGAAAATT
TGTCTACGAAATTCTACTAAAATGATGTCTAGAAAAAACCGGCCTGTGAG
AGAACAAGAATTACAAAAATTAACCGAAAGTTATGGTGAGGTTTCTGATG
ATGATGAATTTGACTTTCCAGAGTTTGACGCGTCCTCTAGTTATTCATAT
TATTCATCAACAGATTCACAAATGTCAGACTTTCATGATAATGACTGTCG
AGTTGAGATTAATAATGTAAACAGTGGTCTTGTAAACAAAATCGACAACA
AATGTAATGATGTCAAAGATGAGTCGTTTATACCAAAAAGTTCGCTATTT
GTCAACAAAAGTCCATCACCAAGTTTCAAATCACAGAATTGCTCAAAAAA
TTGCTCCGAATCCAGCAAATCAGTAGAGAAATCTGAAACCTCGCGTGTGA
ACTCATTGACAAAACGAAATATCAGACTACCCGATTGTATAGTTAAAAGT
AACTTCTGTCCGTCAGCTCTACGCAATCAACCCATTAGAAACTCAATTCC
CCAAGACAGTAATAGTCCTGGCAAGCAGAGAAAACATAAAATCAACATTA
CTTCTCCAAATCTAGCCGACTCTAAATTTCCAACTTGCTCAACTCCGATT
AGAAAATATAAGGAAAACCAAAATGCAAATGTTATAGAGCCTGGAATAGA
AGATAATAACAAAGAAATTCAAAAGTTCAGAGACGCATTTGACTCTGTCG
ACACAGACAGTGATGGACGAATCAGTCCTGAAGAATTGAAAAGAGCCTTT
ACAAAACTCGGGAACATTGTGACAGAAACGGAAATACTTAAAATGATAAA
GGAAGTTGATATTGACCGTAATGGCACTGTAGAATTTAATGAATTTGTCA
TAATGATGCATCATTACACGAAATTCCGATCCGATCATCAAGGCAATGAT
TCAGAAGACTCAGATATTTATGATGCATTTAAAGCTTTCGATCACAATGG
TGATGGGTTTATAGATTCGGACGAAATCAAACGTACAATGGTTGCGTTAG
GCGAAAGCGTATCGGATTCCGACGTCATGGCAATGATTTTCGAGGCTGAT
GCGGATAAAGATGGAAAAATTAATTTCAATGAATTTAAGAAAATTATGCT
AATTTTCAAACAAAGAGCAGCTCAAAAGTAGATTTAAGCTTAGTGAAACT
TACCTATTATTTACTCAAATGATGCGAAATTCGTGCGAGACTTTAAACGA
GAATCACATCAAATTCAACAACCTGACTGATTACATATTCAACTATTTCA
AATATATATTTATACATATATGAAAAGCAATTTTTCAAAAAAAACAAACT
ATTAGAATATTTTTCTATTTTAGCTTAATAAATCGATAATATTTATCGAT
TAAAACAATTTAAAAAAATGTCACTATTGATATTATTTTGTGTTAGATTT
GAGACTGTAATATCTTCTATTCATATGTAGACTAGTATTAGCATTTATTT
ATGCTTCATTTTCTGGAGAGTAATTATTTTTGTAGATATAATTTATTATT
GGTTGTTACGGATGAGAATGTGGTGAAAATAGGTTGTCAATGATGGCTA
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protein sequence of SMED30018233-orf-1

>SMED30018233-orf-1 ID=SMED30018233-orf-1|Name=SMED30018233-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=370bp
MMSRKNRPVREQELQKLTESYGEVSDDDEFDFPEFDASSSYSYYSSTDSQ
MSDFHDNDCRVEINNVNSGLVNKIDNKCNDVKDESFIPKSSLFVNKSPSP
SFKSQNCSKNCSESSKSVEKSETSRVNSLTKRNIRLPDCIVKSNFCPSAL
RNQPIRNSIPQDSNSPGKQRKHKINITSPNLADSKFPTCSTPIRKYKENQ
NANVIEPGIEDNNKEIQKFRDAFDSVDTDSDGRISPEELKRAFTKLGNIV
TETEILKMIKEVDIDRNGTVEFNEFVIMMHHYTKFRSDHQGNDSEDSDIY
DAFKAFDHNGDGFIDSDEIKRTMVALGESVSDSDVMAMIFEADADKDGKI
NFNEFKKIMLIFKQRAAQK*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: molecular function
TermDefinition
GO:0031014troponin T binding
GO:0046872metal ion binding
GO:0005509calcium ion binding
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000099neuron
PLANA:0000418head
Vocabulary: INTERPRO
TermDefinition
IPR002048EF_hand_dom
IPR011992EF-hand-dom_pair
IPR018247EF_Hand_1_Ca_BS
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR002048EF-hand domainSMARTSM00054efh_1coord: 334..362
e-value: 0.0019
score: 27.5
coord: 298..326
e-value: 0.0034
score: 26.6
coord: 254..282
e-value: 1.2E-5
score: 34.8
coord: 218..246
e-value: 1.6E-6
score: 37.6
IPR002048EF-hand domainPFAMPF13499EF-hand_7coord: 297..359
e-value: 1.4E-12
score: 47.9
coord: 217..279
e-value: 1.6E-14
score: 54.1
IPR002048EF-hand domainPROSITEPS50222EF_HAND_2coord: 294..329
score: 14.207
IPR002048EF-hand domainPROSITEPS50222EF_HAND_2coord: 330..365
score: 12.951
IPR002048EF-hand domainPROSITEPS50222EF_HAND_2coord: 250..285
score: 12.7
IPR002048EF-hand domainPROSITEPS50222EF_HAND_2coord: 214..249
score: 15.239
NoneNo IPR availableGENE3DG3DSA:1.10.238.10coord: 287..369
e-value: 2.7E-20
score: 74.4
NoneNo IPR availableGENE3DG3DSA:1.10.238.10coord: 188..286
e-value: 5.9E-24
score: 86.1
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 1..30
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 152..171
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 1..23
NoneNo IPR availablePANTHERPTHR23050:SF330CALMODULIN-LIKE PROTEIN 8coord: 211..362
NoneNo IPR availablePANTHERPTHR23050CALCIUM BINDING PROTEINcoord: 211..362
IPR018247EF-Hand 1, calcium-binding sitePROSITEPS00018EF_HAND_1coord: 263..275
IPR018247EF-Hand 1, calcium-binding sitePROSITEPS00018EF_HAND_1coord: 307..319
IPR018247EF-Hand 1, calcium-binding sitePROSITEPS00018EF_HAND_1coord: 227..239
IPR018247EF-Hand 1, calcium-binding sitePROSITEPS00018EF_HAND_1coord: 343..355
IPR011992EF-hand domain pairSUPERFAMILYSSF47473EF-handcoord: 211..362