slc4a-8
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30018199 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 15
Homology
BLAST of slc4a-8 vs. Ensembl Human
Match: SLC4A11 (solute carrier family 4 member 11 [Source:HGNC Symbol;Acc:HGNC:16438]) HSP 1 Score: 572.392 bits (1474), Expect = 0.000e+0 Identity = 344/822 (41.85%), Postives = 524/822 (63.75%), Query Frame = 2
Query: 449 NMSNISGSTLAYCLQ-----NADETEDDSVP--CLFLSRLEK-IPMKDFSAEVRATLDIQKFLKEAVLLLDMSGSCLEEIIDSMLLTILAN-EVTDAKVSLEALVEEAKKTLFIQS-SYLTYTYQRLAKTIRGLSLSETEGLMTDQSWLCTMCSLNCIHKRHVAIARLNNPVNMGRSSEGIYFIILVVTPTKEKGTKSDIELGRTFATIFADVEFRQQLLFSESVEQFKELLQYHSGDLMEDQAMNRRKSLKVQEVMNQAFHFD------KKYL-VGSGIVSDFKKRFPVYLMDFRDGFRGKG-TIRKVISATIFLYFACLLPSIAFGVLNYNNTEGKIDVRRVIISQAIGGLCFGFFSGQXXXXXXXXXXXXXFVKIISSICNDYDLDFFAMYSCVGLINSLLLILYAMFDISKLMRWSTRSSEEIFALFVAISFVVDAVKDIYKEFSTHYFSCYLSA--NNQSTEHLRLSRFKRAFSGIISNIXXXXXXXXXXXXXXXXXXCQREVSILYLFLVAGTVWLAIQLFTSTKTPFLNNAKREMLTDFALPLAVVIMSLIGTYLFKEIEMQPFVIVEEKVKFEASGILKLPWLAIAGAIALAFPLSLLMFMDQNISSAMVNSPANKLKKGSSYHWDLLVVALINAGLSVFGLPLVHGALPHSPLHVKALADLEERIDTAHHVHQTIVKVRETRITSILSHVFIGISLQMLPIPLIYIPVAVLDGLFVYMAVTTLYGNQFFERILLLFTEQSAYPPSHYLRRVPQRKLHIFTGLQIFQLAGLCLLGFSPSPYLKMGFPLLLLFHMVFRHQVVPRVIDEKYLNALD 2854
N S +SG ++ + + A TE+++ C+ L K + +K+F E+RA D+ FL +A ++L+ + + L+ ++ +ML + + + +L+ L+ LF + + + L+ TI+G++ + T G+ QSWLC +C++ + KRHV I+RL P N G +S + F+ILV+ P K K TK+ +E+ RTFAT+F+D+ FRQ+LL + + E+FKE L + L K + ++ H K ++ G GI D +RFP+Y +DF DG GK + K I+ T+FLYFACLLP+IAFG LN NT+G IDV++ I Q+IGGL + FSGQPL+ILLTTAPLAL++++I IC+DYDLDF + Y+ GL NS L LYA F++S +M RS+EEI ALF++I+FV+DAVK K F +Y+ YL +++ + LS + + + + + +++S Q ++L L ++ GT+WL L+ K+P+L+ RE+L+D ALP+AV+ SLI ++ F+EIEM F + F + I L A++GA+ L F LS+L F++QN+ +A+VN+P N+L KG++YHWDLL++A+IN GLS+FGLP +H A PHSPLHV+ALA +EER++ H++ TIV V+ETR+TS+ + V +G+SL +LP+PL +IP VL GLF+Y+A+T+L GNQ +R+ LL EQ+AYPP+HY+RRVPQRK+H FTGLQ+ QL LC G S PY+KM FPL+++ + R+ ++PR+I+ KYL+ +D
Sbjct: 56 NSSIVSGESIRFFVNVNLEMQATNTENEATSGGCVLLHTSRKYLKLKNFKEEIRAHRDLDGFLAQASIVLNETATSLDNVLRTMLRRFARDPDNNEPNCNLDLLM----AMLFTDAGAPMRGKVHLLSDTIQGVTATVT-GVRYQQSWLCIICTMKALQKRHVCISRLVRPQNWGENSCEVRFVILVLAPPKMKSTKTAMEVARTFATMFSDIAFRQKLLETRTEEEFKEALVHQRQLLTMVSHGPVAPRTKERSTVSLPAHRHPEPPKCKDFVPFGKGIREDIARRFPLYPLDFTDGIIGKNKAVGKYITTTLFLYFACLLPTIAFGSLNDENTDGAIDVQKTIAGQSIGGLLYALFSGQPLVILLTTAPLALYIQVIRVICDDYDLDFNSFYAWTGLWNSFFLALYAFFNLSLVMSLFKRSTEEIIALFISITFVLDAVKGTVKIFWKYYYGHYLDDYHTKRTSSLVSLSGLGASLNASLHTALNASFLASPTELPSATHSGQ-ATAVLSLLIMLGTLWLGYTLYQFKKSPYLHPCVREILSDCALPIAVLAFSLISSHGFREIEMSKFRYNPSESPFAMAQIQSLSLRAVSGAMGLGFLLSMLFFIEQNLVAALVNAPENRLVKGTAYHWDLLLLAIINTGLSLFGLPWIHAAYPHSPLHVRALALVEERVENG-HIYDTIVNVKETRLTSLGASVLVGLSLLLLPVPLQWIPKPVLYGLFLYIALTSLDGNQLVQRVALLLKEQTAYPPTHYIRRVPQRKIHYFTGLQVLQLLLLCAFGMSSLPYMKMIFPLIMIAMIPIRYILLPRIIEAKYLDVMD 870
BLAST of slc4a-8 vs. Ensembl Human
Match: SLC4A11 (solute carrier family 4 member 11 [Source:HGNC Symbol;Acc:HGNC:16438]) HSP 1 Score: 572.007 bits (1473), Expect = 0.000e+0 Identity = 344/822 (41.85%), Postives = 524/822 (63.75%), Query Frame = 2
Query: 449 NMSNISGSTLAYCLQ-----NADETEDDSVP--CLFLSRLEK-IPMKDFSAEVRATLDIQKFLKEAVLLLDMSGSCLEEIIDSMLLTILAN-EVTDAKVSLEALVEEAKKTLFIQS-SYLTYTYQRLAKTIRGLSLSETEGLMTDQSWLCTMCSLNCIHKRHVAIARLNNPVNMGRSSEGIYFIILVVTPTKEKGTKSDIELGRTFATIFADVEFRQQLLFSESVEQFKELLQYHSGDLMEDQAMNRRKSLKVQEVMNQAFHFD------KKYL-VGSGIVSDFKKRFPVYLMDFRDGFRGKG-TIRKVISATIFLYFACLLPSIAFGVLNYNNTEGKIDVRRVIISQAIGGLCFGFFSGQXXXXXXXXXXXXXFVKIISSICNDYDLDFFAMYSCVGLINSLLLILYAMFDISKLMRWSTRSSEEIFALFVAISFVVDAVKDIYKEFSTHYFSCYLSA--NNQSTEHLRLSRFKRAFSGIISNIXXXXXXXXXXXXXXXXXXCQREVSILYLFLVAGTVWLAIQLFTSTKTPFLNNAKREMLTDFALPLAVVIMSLIGTYLFKEIEMQPFVIVEEKVKFEASGILKLPWLAIAGAIALAFPLSLLMFMDQNISSAMVNSPANKLKKGSSYHWDLLVVALINAGLSVFGLPLVHGALPHSPLHVKALADLEERIDTAHHVHQTIVKVRETRITSILSHVFIGISLQMLPIPLIYIPVAVLDGLFVYMAVTTLYGNQFFERILLLFTEQSAYPPSHYLRRVPQRKLHIFTGLQIFQLAGLCLLGFSPSPYLKMGFPLLLLFHMVFRHQVVPRVIDEKYLNALD 2854
N S +SG ++ + + A TE+++ C+ L K + +K+F E+RA D+ FL +A ++L+ + + L+ ++ +ML + + + +L+ L+ LF + + + L+ TI+G++ + T G+ QSWLC +C++ + KRHV I+RL P N G +S + F+ILV+ P K K TK+ +E+ RTFAT+F+D+ FRQ+LL + + E+FKE L + L K + ++ H K ++ G GI D +RFP+Y +DF DG GK + K I+ T+FLYFACLLP+IAFG LN NT+G IDV++ I Q+IGGL + FSGQPL+ILLTTAPLAL++++I IC+DYDLDF + Y+ GL NS L LYA F++S +M RS+EEI ALF++I+FV+DAVK K F +Y+ YL +++ + LS + + + + + +++S Q ++L L ++ GT+WL L+ K+P+L+ RE+L+D ALP+AV+ SLI ++ F+EIEM F + F + I L A++GA+ L F LS+L F++QN+ +A+VN+P N+L KG++YHWDLL++A+IN GLS+FGLP +H A PHSPLHV+ALA +EER++ H++ TIV V+ETR+TS+ + V +G+SL +LP+PL +IP VL GLF+Y+A+T+L GNQ +R+ LL EQ+AYPP+HY+RRVPQRK+H FTGLQ+ QL LC G S PY+KM FPL+++ + R+ ++PR+I+ KYL+ +D
Sbjct: 99 NSSIVSGESIRFFVNVNLEMQATNTENEATSGGCVLLHTSRKYLKLKNFKEEIRAHRDLDGFLAQASIVLNETATSLDNVLRTMLRRFARDPDNNEPNCNLDLLM----AMLFTDAGAPMRGKVHLLSDTIQGVTATVT-GVRYQQSWLCIICTMKALQKRHVCISRLVRPQNWGENSCEVRFVILVLAPPKMKSTKTAMEVARTFATMFSDIAFRQKLLETRTEEEFKEALVHQRQLLTMVSHGPVAPRTKERSTVSLPAHRHPEPPKCKDFVPFGKGIREDIARRFPLYPLDFTDGIIGKNKAVGKYITTTLFLYFACLLPTIAFGSLNDENTDGAIDVQKTIAGQSIGGLLYALFSGQPLVILLTTAPLALYIQVIRVICDDYDLDFNSFYAWTGLWNSFFLALYAFFNLSLVMSLFKRSTEEIIALFISITFVLDAVKGTVKIFWKYYYGHYLDDYHTKRTSSLVSLSGLGASLNASLHTALNASFLASPTELPSATHSGQ-ATAVLSLLIMLGTLWLGYTLYQFKKSPYLHPCVREILSDCALPIAVLAFSLISSHGFREIEMSKFRYNPSESPFAMAQIQSLSLRAVSGAMGLGFLLSMLFFIEQNLVAALVNAPENRLVKGTAYHWDLLLLAIINTGLSLFGLPWIHAAYPHSPLHVRALALVEERVENG-HIYDTIVNVKETRLTSLGASVLVGLSLLLLPVPLQWIPKPVLYGLFLYIALTSLDGNQLVQRVALLLKEQTAYPPTHYIRRVPQRKIHYFTGLQVLQLLLLCAFGMSSLPYMKMIFPLIMIAMIPIRYILLPRIIEAKYLDVMD 913
BLAST of slc4a-8 vs. Ensembl Human
Match: SLC4A11 (solute carrier family 4 member 11 [Source:HGNC Symbol;Acc:HGNC:16438]) HSP 1 Score: 571.622 bits (1472), Expect = 0.000e+0 Identity = 344/822 (41.85%), Postives = 524/822 (63.75%), Query Frame = 2
Query: 449 NMSNISGSTLAYCLQ-----NADETEDDSVP--CLFLSRLEK-IPMKDFSAEVRATLDIQKFLKEAVLLLDMSGSCLEEIIDSMLLTILAN-EVTDAKVSLEALVEEAKKTLFIQS-SYLTYTYQRLAKTIRGLSLSETEGLMTDQSWLCTMCSLNCIHKRHVAIARLNNPVNMGRSSEGIYFIILVVTPTKEKGTKSDIELGRTFATIFADVEFRQQLLFSESVEQFKELLQYHSGDLMEDQAMNRRKSLKVQEVMNQAFHFD------KKYL-VGSGIVSDFKKRFPVYLMDFRDGFRGKG-TIRKVISATIFLYFACLLPSIAFGVLNYNNTEGKIDVRRVIISQAIGGLCFGFFSGQXXXXXXXXXXXXXFVKIISSICNDYDLDFFAMYSCVGLINSLLLILYAMFDISKLMRWSTRSSEEIFALFVAISFVVDAVKDIYKEFSTHYFSCYLSA--NNQSTEHLRLSRFKRAFSGIISNIXXXXXXXXXXXXXXXXXXCQREVSILYLFLVAGTVWLAIQLFTSTKTPFLNNAKREMLTDFALPLAVVIMSLIGTYLFKEIEMQPFVIVEEKVKFEASGILKLPWLAIAGAIALAFPLSLLMFMDQNISSAMVNSPANKLKKGSSYHWDLLVVALINAGLSVFGLPLVHGALPHSPLHVKALADLEERIDTAHHVHQTIVKVRETRITSILSHVFIGISLQMLPIPLIYIPVAVLDGLFVYMAVTTLYGNQFFERILLLFTEQSAYPPSHYLRRVPQRKLHIFTGLQIFQLAGLCLLGFSPSPYLKMGFPLLLLFHMVFRHQVVPRVIDEKYLNALD 2854
N S +SG ++ + + A TE+++ C+ L K + +K+F E+RA D+ FL +A ++L+ + + L+ ++ +ML + + + +L+ L+ LF + + + L+ TI+G++ + T G+ QSWLC +C++ + KRHV I+RL P N G +S + F+ILV+ P K K TK+ +E+ RTFAT+F+D+ FRQ+LL + + E+FKE L + L K + ++ H K ++ G GI D +RFP+Y +DF DG GK + K I+ T+FLYFACLLP+IAFG LN NT+G IDV++ I Q+IGGL + FSGQPL+ILLTTAPLAL++++I IC+DYDLDF + Y+ GL NS L LYA F++S +M RS+EEI ALF++I+FV+DAVK K F +Y+ YL +++ + LS + + + + + +++S Q ++L L ++ GT+WL L+ K+P+L+ RE+L+D ALP+AV+ SLI ++ F+EIEM F + F + I L A++GA+ L F LS+L F++QN+ +A+VN+P N+L KG++YHWDLL++A+IN GLS+FGLP +H A PHSPLHV+ALA +EER++ H++ TIV V+ETR+TS+ + V +G+SL +LP+PL +IP VL GLF+Y+A+T+L GNQ +R+ LL EQ+AYPP+HY+RRVPQRK+H FTGLQ+ QL LC G S PY+KM FPL+++ + R+ ++PR+I+ KYL+ +D
Sbjct: 72 NSSIVSGESIRFFVNVNLEMQATNTENEATSGGCVLLHTSRKYLKLKNFKEEIRAHRDLDGFLAQASIVLNETATSLDNVLRTMLRRFARDPDNNEPNCNLDLLM----AMLFTDAGAPMRGKVHLLSDTIQGVTATVT-GVRYQQSWLCIICTMKALQKRHVCISRLVRPQNWGENSCEVRFVILVLAPPKMKSTKTAMEVARTFATMFSDIAFRQKLLETRTEEEFKEALVHQRQLLTMVSHGPVAPRTKERSTVSLPAHRHPEPPKCKDFVPFGKGIREDIARRFPLYPLDFTDGIIGKNKAVGKYITTTLFLYFACLLPTIAFGSLNDENTDGAIDVQKTIAGQSIGGLLYALFSGQPLVILLTTAPLALYIQVIRVICDDYDLDFNSFYAWTGLWNSFFLALYAFFNLSLVMSLFKRSTEEIIALFISITFVLDAVKGTVKIFWKYYYGHYLDDYHTKRTSSLVSLSGLGASLNASLHTALNASFLASPTELPSATHSGQ-ATAVLSLLIMLGTLWLGYTLYQFKKSPYLHPCVREILSDCALPIAVLAFSLISSHGFREIEMSKFRYNPSESPFAMAQIQSLSLRAVSGAMGLGFLLSMLFFIEQNLVAALVNAPENRLVKGTAYHWDLLLLAIINTGLSLFGLPWIHAAYPHSPLHVRALALVEERVENG-HIYDTIVNVKETRLTSLGASVLVGLSLLLLPVPLQWIPKPVLYGLFLYIALTSLDGNQLVQRVALLLKEQTAYPPTHYIRRVPQRKIHYFTGLQVLQLLLLCAFGMSSLPYMKMIFPLIMIAMIPIRYILLPRIIEAKYLDVMD 886
BLAST of slc4a-8 vs. Ensembl Human
Match: SLC4A11 (solute carrier family 4 member 11 [Source:HGNC Symbol;Acc:HGNC:16438]) HSP 1 Score: 552.747 bits (1423), Expect = 0.000e+0 Identity = 317/696 (45.55%), Postives = 464/696 (66.67%), Query Frame = 2
Query: 797 LAKTIRGLSLSETEGLMTDQSWLCTMCSLNCIHKRHVAIARLNNPVNMGRSSEGIYFIILVVTPTKEKGTKSDIELGRTFATIFADVEFRQQLLFSESVEQFKELLQYHSGDLMEDQAMNRRKSLKVQEVMNQAFHFD------KKYL-VGSGIVSDFKKRFPVYLMDFRDGFRGKG-TIRKVISATIFLYFACLLPSIAFGVLNYNNTEGKIDVRRVIISQAIGGLCFGFFSGQXXXXXXXXXXXXXFVKIISSICNDYDLDFFAMYSCVGLINSLLLILYAMFDISKLMRWSTRSSEEIFALFVAISFVVDAVKDIYKEFSTHYFSCYLS--ANNQSTEHLRLSRFKRAFSGIISNIXXXXXXXXXXXXXXXXXXCQREVSILYLFLVAGTVWLAIQLFTSTKTPFLNNAKREMLTDFALPLAVVIMSLIGTYLFKEIEMQPFVIVEEKVKFEASGILKLPWLAIAGAIALAFPLSLLMFMDQNISSAMVNSPANKLKKGSSYHWDLLVVALINAGLSVFGLPLVHGALPHSPLHVKALADLEERIDTAHHVHQTIVKVRETRITSILSHVFIGISLQMLPIPLIYIPVAVLDGLFVYMAVTTLYGNQFFERILLLFTEQSAYPPSHYLRRVPQRKLHIFTGLQIFQLAGLCLLGFSPSPYLKMGFPLLLLFHMVFRHQVVPRVIDEKYLNALD 2854
L+ TI+G++ + T G+ QSWLC +C++ + KRHV I+RL P N G +S + F+ILV+ P K K TK+ +E+ RTFAT+F+D+ FRQ+LL + + E+FKE L + L K + ++ H K ++ G GI D +RFP+Y +DF DG GK + K I+ T+FLYFACLLP+IAFG LN NT+G IDV++ I Q+IGGL + FSGQPL+ILLTTAPLAL++++I IC+DYDLDF + Y+ GL NS L LYA F++S +M RS+EEI ALF++I+FV+DAVK K F +Y+ YL +++ + LS + + + + + +++S Q ++L L ++ GT+WL L+ K+P+L+ RE+L+D ALP+AV+ SLI ++ F+EIEM F + F + I L A++GA+ L F LS+L F++QN+ +A+VN+P N+L KG++YHWDLL++A+IN GLS+FGLP +H A PHSPLHV+ALA +EER++ H++ TIV V+ETR+TS+ + V +G+SL +LP+PL +IP VL GLF+Y+A+T+L GNQ +R+ LL EQ+AYPP+HY+RRVPQRK+H FTGLQ+ QL LC G S PY+KM FPL+++ + R+ ++PR+I+ KYL+ +D
Sbjct: 155 LSDTIQGVTATVT-GVRYQQSWLCIICTMKALQKRHVCISRLVRPQNWGENSCEVRFVILVLAPPKMKSTKTAMEVARTFATMFSDIAFRQKLLETRTEEEFKEALVHQRQLLTMVSHGPVAPRTKERSTVSLPAHRHPEPPKCKDFVPFGKGIREDIARRFPLYPLDFTDGIIGKNKAVGKYITTTLFLYFACLLPTIAFGSLNDENTDGAIDVQKTIAGQSIGGLLYALFSGQPLVILLTTAPLALYIQVIRVICDDYDLDFNSFYAWTGLWNSFFLALYAFFNLSLVMSLFKRSTEEIIALFISITFVLDAVKGTVKIFWKYYYGHYLDDYHTKRTSSLVSLSGLGASLNASLHTALNASFLASPTELPSATHSGQ-ATAVLSLLIMLGTLWLGYTLYQFKKSPYLHPCVREILSDCALPIAVLAFSLISSHGFREIEMSKFRYNPSESPFAMAQIQSLSLRAVSGAMGLGFLLSMLFFIEQNLVAALVNAPENRLVKGTAYHWDLLLLAIINTGLSLFGLPWIHAAYPHSPLHVRALALVEERVENG-HIYDTIVNVKETRLTSLGASVLVGLSLLLLPVPLQWIPKPVLYGLFLYIALTSLDGNQLVQRVALLLKEQTAYPPTHYIRRVPQRKIHYFTGLQVLQLLLLCAFGMSSLPYMKMIFPLIMIAMIPIRYILLPRIIEAKYLDVMD 847
BLAST of slc4a-8 vs. Ensembl Human
Match: SLC4A11 (solute carrier family 4 member 11 [Source:HGNC Symbol;Acc:HGNC:16438]) HSP 1 Score: 528.48 bits (1360), Expect = 1.323e-173 Identity = 320/822 (38.93%), Postives = 492/822 (59.85%), Query Frame = 2
Query: 449 NMSNISGSTLAYCLQ-----NADETEDDSVP--CLFLSRLEK-IPMKDFSAEVRATLDIQKFLKEAVLLLDMSGSCLEEIIDSMLLTILAN-EVTDAKVSLEALVEEAKKTLFIQS-SYLTYTYQRLAKTIRGLSLSETEGLMTDQSWLCTMCSLNCIHKRHVAIARLNNPVNMGRSSEGIYFIILVVTPTKEKGTKSDIELGRTFATIFADVEFRQQLLFSESVEQFKELLQYHSGDLMEDQAMNRRKSLKVQEVMNQAFHFD------KKYL-VGSGIVSDFKKRFPVYLMDFRDGFRGKG-TIRKVISATIFLYFACLLPSIAFGVLNYNNTEGKIDVRRVIISQAIGGLCFGFFSGQXXXXXXXXXXXXXFVKIISSICNDYDLDFFAMYSCVGLINSLLLILYAMFDISKLMRWSTRSSEEIFALFVAISFVVDAVKDIYKEFSTHYFSCYLS--ANNQSTEHLRLSRFKRAFSGIISNIXXXXXXXXXXXXXXXXXXCQREVSILYLFLVAGTVWLAIQLFTSTKTPFLNNAKREMLTDFALPLAVVIMSLIGTYLFKEIEMQPFVIVEEKVKFEASGILKLPWLAIAGAIALAFPLSLLMFMDQNISSAMVNSPANKLKKGSSYHWDLLVVALINAGLSVFGLPLVHGALPHSPLHVKALADLEERIDTAHHVHQTIVKVRETRITSILSHVFIGISLQMLPIPLIYIPVAVLDGLFVYMAVTTLYGNQFFERILLLFTEQSAYPPSHYLRRVPQRKLHIFTGLQIFQLAGLCLLGFSPSPYLKMGFPLLLLFHMVFRHQVVPRVIDEKYLNALD 2854
N S +SG ++ + + A TE+++ C+ L K + +K+F E+RA D+ FL +A ++L+ + + L+ ++ +ML + + + +L+ L+ LF + + + L+ TI+G++ + T G+ QSWLC +C++ + KRHV I+RL P N G +S + F+ILV+ P K K TK+ +E+ RTFAT+F+D+ FRQ+LL + + E+FKE L + L K + ++ H K ++ G GI D +RFP+Y +DF DG GK + K I+ T+FLYFACLLP+IAFG LN NT+G I +I IC+DYDLDF + Y+ GL NS L LYA F++S +M RS+EEI ALF++I+FV+DAVK K F +Y+ YL +++ + LS + + + + + +++S Q ++L L ++ GT+WL L+ K+P+L+ RE+L+D ALP+AV+ SLI ++ F+EIEM F + F + I L A++GA+ L F LS+L F++QN+ +A+VN+P N+L KG++YHWDLL++A+IN GLS+FGLP +H A PHSPLHV+ALA +EER++ H++ TIV V+ETR+TS+ + V +G+SL +LP+PL +IP VL GLF+Y+A+T+L GNQ +R+ LL EQ+AYPP+HY+RRVPQRK+H FTGLQ+ QL LC G S PY+KM FPL+++ + R+ ++PR+I+ KYL+ +D
Sbjct: 56 NSSIVSGESIRFFVNVNLEMQATNTENEATSGGCVLLHTSRKYLKLKNFKEEIRAHRDLDGFLAQASIVLNETATSLDNVLRTMLRRFARDPDNNEPNCNLDLLM----AMLFTDAGAPMRGKVHLLSDTIQGVTATVT-GVRYQQSWLCIICTMKALQKRHVCISRLVRPQNWGENSCEVRFVILVLAPPKMKSTKTAMEVARTFATMFSDIAFRQKLLETRTEEEFKEALVHQRQLLTMVSHGPVAPRTKERSTVSLPAHRHPEPPKCKDFVPFGKGIREDIARRFPLYPLDFTDGIIGKNKAVGKYITTTLFLYFACLLPTIAFGSLNDENTDGAI--------------------------------------VIRVICDDYDLDFNSFYAWTGLWNSFFLALYAFFNLSLVMSLFKRSTEEIIALFISITFVLDAVKGTVKIFWKYYYGHYLDDYHTKRTSSLVSLSGLGASLNASLHTALNASFLASPTELPSATHSGQ-ATAVLSLLIMLGTLWLGYTLYQFKKSPYLHPCVREILSDCALPIAVLAFSLISSHGFREIEMSKFRYNPSESPFAMAQIQSLSLRAVSGAMGLGFLLSMLFFIEQNLVAALVNAPENRLVKGTAYHWDLLLLAIINTGLSLFGLPWIHAAYPHSPLHVRALALVEERVENG-HIYDTIVNVKETRLTSLGASVLVGLSLLLLPVPLQWIPKPVLYGLFLYIALTSLDGNQLVQRVALLLKEQTAYPPTHYIRRVPQRKIHYFTGLQVLQLLLLCAFGMSSLPYMKMIFPLIMIAMIPIRYILLPRIIEAKYLDVMD 832
BLAST of slc4a-8 vs. Ensembl Celegans
Match: abts-3 (Anion/Bicarbonate TranSporter family [Source:UniProtKB/TrEMBL;Acc:A0A3B1E4W4]) HSP 1 Score: 669.078 bits (1725), Expect = 0.000e+0 Identity = 365/789 (46.26%), Postives = 528/789 (66.92%), Query Frame = 2
Query: 509 EDDSVPCLFLSRLEKIPMKDFSAEVRATLDIQKFLKEAVLLLDMSGSCLEEIIDSMLLTILANEVTDAKVSLEALVEEAKKTLFIQSSYLTYTYQRLAKTIRGLSLSETEG--LMTDQSWLCTMCSLNCIHKRHVAIARLNNPVNMGRSSEGIYFIILVVTPTKEKGTKSDIELGRTFATIFADVEFRQQLLFSESVEQFKELLQYHSGDLMEDQAM--NRRKSLKVQEVMNQAFHFDKKYLVGSGIVSDFKKRFPVYLMDFRDGFRGKGTIRKVISATIFLYFACLLPSIAFGVLNYNNTEGKIDVRRVIISQAIGGLCFGFFSGQXXXXXXXXXXXXXFVKIISSICNDYDLDFFAMYSCVGLINSLLLILYAMFDISKLMRWSTRSSEEIFALFVAISFVVDAVKDIYKEFSTHYFSCYLSANNQSTEHLRLSRFKRAFSG--IISNIXXXXXXXXXXXXXXXXXXCQREVSILYLFLVAGTVWLAIQLFTSTKTPFLNNAKREMLTDFALPLAVVIMSLIGTYLFKEIEMQPFVIVEEKVKFEASGILKLPWLAIAGAIALAFPLSLLMFMDQNISSAMVNSPANKLKKGSSYHWDLLVVALINAGLSVFGLPLVHGALPHSPLHVKALADLEERIDTAHHVHQTIVKVRETRITSILSHVFIGISLQML-PIPLIYIPVAVLDGLFVYMAVTTLYGNQFFERILLLFTEQSAYPPSHYLRRVPQRKLHIFTGLQIFQLAGLCLLGFSPSPYLKMGFPLLLLFHMVFRHQVVPRVIDEKYLNALD 2854
E D+V L ++ EKIPMKDF +E+RAT+DI L +AVLLLD+ + LEEI ++ + E E E+ + LF Q + + L++T++ + + + G DQ+W+C +C LN + RHVAIARL++P N+GR+ + + FII+V+ P++ KGTK+ +E RTFAT+FAD+E RQ+L+ ++SVEQF+ L + +L DQ R+ S+ + Q F + Y G+V +FK+R +Y D+ DG RG T++K+ S +FLYFACLLP+IAFGVLN +NT+G I+VR+VII+QAIGG+ F F GQP+IILLTT PLA+++K+I I + DF AMY+CVGL + LILY+ ++ LM+++TRS+EE+F+LF+AI+F V++++ I+ F +Y C SA + L+ FK + I+ NI T+ S + + C+R+ SILY+ L+ GT+WL + L+ KTP+L ++RE L D+ALP +V+IMS G+Y F +IE F + E + + + LP + L F LS L F+DQNI+SA+VN+ NKLKKG+S++ DL VVAL+N LSVFGLP +HGALPHSPLH++ALAD+EER+ HVH+ I+ VRETR+ S+++HV I +S+ L P PL IP +VL GLF+YMA+T+L GN+ FER+LLL TEQ AYPP+HY+R+VPQRK+H+FT Q+ QL LC GFSP P+++M FP++ F + RH ++PR+ID KYL+ALD
Sbjct: 270 EYDNV-TLMYAKHEKIPMKDFGSEIRATMDIDHLLNKAVLLLDLQETSLEEIFAKIIHEMDIQEP-------EFTSEQVRSVLFTQDA--GNQFHILSRTVQSICTTGSVGGSFDYDQTWICALCMLNTVQHRHVAIARLSHPTNLGRTMQDLRFIIIVIAPSRAKGTKTALETTRTFATLFADMEIRQRLVMAQSVEQFRSTLLSAAKELAMDQNQWRERKSSIHLSHAKEQIFGPEAWYPF-RGLVEEFKRRLAIYPSDYLDGIRGHKTVQKLFSTVVFLYFACLLPAIAFGVLNDDNTKGAINVRKVIIAQAIGGIFFSLFGGQPMIILLTTVPLAIYIKVIFKISQELGYDFLAMYACVGLFCQMFLILYSATELCSLMKFATRSAEEMFSLFIAIAFTVESIRAIHNSFKKNYNDCDTSAISMKAARTALNAFKNGSNADSIVGNI------TSSMSIGDTGSLCRRDTSILYMLLMFGTLWLGLFLYNFRKTPYLTRSRREWLADYALPASVLIMSFTGSYAFSDIEKDRFNLRFEFPLIQMADVTSLPPSGYFVCLLLGFSLSFLFFIDQNITSAIVNNNQNKLKKGTSHNLDLFVVALLNMFLSVFGLPWMHGALPHSPLHLRALADVEERVSQG-HVHEVIMNVRETRLASLIAHVMILVSMFFLIPYPLQLIPTSVLHGLFLYMALTSLSGNEMFERLLLLITEQQAYPPTHYIRKVPQRKVHLFTACQLLQLIILCAFGFSPYPFIEMVFPIVCFFFLPIRHTLIPRLIDYKYLDALD 1040
BLAST of slc4a-8 vs. Ensembl Celegans
Match: abts-3 (Anion/Bicarbonate TranSporter family [Source:UniProtKB/TrEMBL;Acc:A0A3B1E4W4]) HSP 1 Score: 669.078 bits (1725), Expect = 0.000e+0 Identity = 362/782 (46.29%), Postives = 524/782 (67.01%), Query Frame = 2
Query: 530 LFLSRLEKIPMKDFSAEVRATLDIQKFLKEAVLLLDMSGSCLEEIIDSMLLTILANEVTDAKVSLEALVEEAKKTLFIQSSYLTYTYQRLAKTIRGLSLSETEG--LMTDQSWLCTMCSLNCIHKRHVAIARLNNPVNMGRSSEGIYFIILVVTPTKEKGTKSDIELGRTFATIFADVEFRQQLLFSESVEQFKELLQYHSGDLMEDQAM--NRRKSLKVQEVMNQAFHFDKKYLVGSGIVSDFKKRFPVYLMDFRDGFRGKGTIRKVISATIFLYFACLLPSIAFGVLNYNNTEGKIDVRRVIISQAIGGLCFGFFSGQXXXXXXXXXXXXXFVKIISSICNDYDLDFFAMYSCVGLINSLLLILYAMFDISKLMRWSTRSSEEIFALFVAISFVVDAVKDIYKEFSTHYFSCYLSANNQSTEHLRLSRFKRAFSG--IISNIXXXXXXXXXXXXXXXXXXCQREVSILYLFLVAGTVWLAIQLFTSTKTPFLNNAKREMLTDFALPLAVVIMSLIGTYLFKEIEMQPFVIVEEKVKFEASGILKLPWLAIAGAIALAFPLSLLMFMDQNISSAMVNSPANKLKKGSSYHWDLLVVALINAGLSVFGLPLVHGALPHSPLHVKALADLEERIDTAHHVHQTIVKVRETRITSILSHVFIGISLQML-PIPLIYIPVAVLDGLFVYMAVTTLYGNQFFERILLLFTEQSAYPPSHYLRRVPQRKLHIFTGLQIFQLAGLCLLGFSPSPYLKMGFPLLLLFHMVFRHQVVPRVIDEKYLNALD 2854
L ++ EKIPMKDF +E+RAT+DI L +AVLLLD+ + LEEI ++ + E E E+ + LF Q + + L++T++ + + + G DQ+W+C +C LN + RHVAIARL++P N+GR+ + + FII+V+ P++ KGTK+ +E RTFAT+FAD+E RQ+L+ ++SVEQF+ L + +L DQ R+ S+ + Q F + Y G+V +FK+R +Y D+ DG RG T++K+ S +FLYFACLLP+IAFGVLN +NT+G I+VR+VII+QAIGG+ F F GQP+IILLTT PLA+++K+I I + DF AMY+CVGL + LILY+ ++ LM+++TRS+EE+F+LF+AI+F V++++ I+ F +Y C SA + L+ FK + I+ NI T+ S + + C+R+ SILY+ L+ GT+WL + L+ KTP+L ++RE L D+ALP +V+IMS G+Y F +IE F + E + + + LP + L F LS L F+DQNI+SA+VN+ NKLKKG+S++ DL VVAL+N LSVFGLP +HGALPHSPLH++ALAD+EER+ HVH+ I+ VRETR+ S+++HV I +S+ L P PL IP +VL GLF+YMA+T+L GN+ FER+LLL TEQ AYPP+HY+R+VPQRK+H+FT Q+ QL LC GFSP P+++M FP++ F + RH ++PR+ID KYL+ALD
Sbjct: 192 LMYAKHEKIPMKDFGSEIRATMDIDHLLNKAVLLLDLQETSLEEIFAKIIHEMDIQEP-------EFTSEQVRSVLFTQDA--GNQFHILSRTVQSICTTGSVGGSFDYDQTWICALCMLNTVQHRHVAIARLSHPTNLGRTMQDLRFIIIVIAPSRAKGTKTALETTRTFATLFADMEIRQRLVMAQSVEQFRSTLLSAAKELAMDQNQWRERKSSIHLSHAKEQIFGPEAWYPF-RGLVEEFKRRLAIYPSDYLDGIRGHKTVQKLFSTVVFLYFACLLPAIAFGVLNDDNTKGAINVRKVIIAQAIGGIFFSLFGGQPMIILLTTVPLAIYIKVIFKISQELGYDFLAMYACVGLFCQMFLILYSATELCSLMKFATRSAEEMFSLFIAIAFTVESIRAIHNSFKKNYNDCDTSAISMKAARTALNAFKNGSNADSIVGNI------TSSMSIGDTGSLCRRDTSILYMLLMFGTLWLGLFLYNFRKTPYLTRSRREWLADYALPASVLIMSFTGSYAFSDIEKDRFNLRFEFPLIQMADVTSLPPSGYFVCLLLGFSLSFLFFIDQNITSAIVNNNQNKLKKGTSHNLDLFVVALLNMFLSVFGLPWMHGALPHSPLHLRALADVEERVSQG-HVHEVIMNVRETRLASLIAHVMILVSMFFLIPYPLQLIPTSVLHGLFLYMALTSLSGNEMFERLLLLITEQQAYPPTHYIRKVPQRKVHLFTACQLLQLIILCAFGFSPYPFIEMVFPIVCFFFLPIRHTLIPRLIDYKYLDALD 956
BLAST of slc4a-8 vs. Ensembl Celegans
Match: abts-3 (Anion/Bicarbonate TranSporter family [Source:UniProtKB/TrEMBL;Acc:A0A3B1E4W4]) HSP 1 Score: 668.307 bits (1723), Expect = 0.000e+0 Identity = 362/782 (46.29%), Postives = 524/782 (67.01%), Query Frame = 2
Query: 530 LFLSRLEKIPMKDFSAEVRATLDIQKFLKEAVLLLDMSGSCLEEIIDSMLLTILANEVTDAKVSLEALVEEAKKTLFIQSSYLTYTYQRLAKTIRGLSLSETEG--LMTDQSWLCTMCSLNCIHKRHVAIARLNNPVNMGRSSEGIYFIILVVTPTKEKGTKSDIELGRTFATIFADVEFRQQLLFSESVEQFKELLQYHSGDLMEDQAM--NRRKSLKVQEVMNQAFHFDKKYLVGSGIVSDFKKRFPVYLMDFRDGFRGKGTIRKVISATIFLYFACLLPSIAFGVLNYNNTEGKIDVRRVIISQAIGGLCFGFFSGQXXXXXXXXXXXXXFVKIISSICNDYDLDFFAMYSCVGLINSLLLILYAMFDISKLMRWSTRSSEEIFALFVAISFVVDAVKDIYKEFSTHYFSCYLSANNQSTEHLRLSRFKRAFSG--IISNIXXXXXXXXXXXXXXXXXXCQREVSILYLFLVAGTVWLAIQLFTSTKTPFLNNAKREMLTDFALPLAVVIMSLIGTYLFKEIEMQPFVIVEEKVKFEASGILKLPWLAIAGAIALAFPLSLLMFMDQNISSAMVNSPANKLKKGSSYHWDLLVVALINAGLSVFGLPLVHGALPHSPLHVKALADLEERIDTAHHVHQTIVKVRETRITSILSHVFIGISLQML-PIPLIYIPVAVLDGLFVYMAVTTLYGNQFFERILLLFTEQSAYPPSHYLRRVPQRKLHIFTGLQIFQLAGLCLLGFSPSPYLKMGFPLLLLFHMVFRHQVVPRVIDEKYLNALD 2854
L ++ EKIPMKDF +E+RAT+DI L +AVLLLD+ + LEEI ++ + E E E+ + LF Q + + L++T++ + + + G DQ+W+C +C LN + RHVAIARL++P N+GR+ + + FII+V+ P++ KGTK+ +E RTFAT+FAD+E RQ+L+ ++SVEQF+ L + +L DQ R+ S+ + Q F + Y G+V +FK+R +Y D+ DG RG T++K+ S +FLYFACLLP+IAFGVLN +NT+G I+VR+VII+QAIGG+ F F GQP+IILLTT PLA+++K+I I + DF AMY+CVGL + LILY+ ++ LM+++TRS+EE+F+LF+AI+F V++++ I+ F +Y C SA + L+ FK + I+ NI T+ S + + C+R+ SILY+ L+ GT+WL + L+ KTP+L ++RE L D+ALP +V+IMS G+Y F +IE F + E + + + LP + L F LS L F+DQNI+SA+VN+ NKLKKG+S++ DL VVAL+N LSVFGLP +HGALPHSPLH++ALAD+EER+ HVH+ I+ VRETR+ S+++HV I +S+ L P PL IP +VL GLF+YMA+T+L GN+ FER+LLL TEQ AYPP+HY+R+VPQRK+H+FT Q+ QL LC GFSP P+++M FP++ F + RH ++PR+ID KYL+ALD
Sbjct: 111 LMYAKHEKIPMKDFGSEIRATMDIDHLLNKAVLLLDLQETSLEEIFAKIIHEMDIQEP-------EFTSEQVRSVLFTQDA--GNQFHILSRTVQSICTTGSVGGSFDYDQTWICALCMLNTVQHRHVAIARLSHPTNLGRTMQDLRFIIIVIAPSRAKGTKTALETTRTFATLFADMEIRQRLVMAQSVEQFRSTLLSAAKELAMDQNQWRERKSSIHLSHAKEQIFGPEAWYPF-RGLVEEFKRRLAIYPSDYLDGIRGHKTVQKLFSTVVFLYFACLLPAIAFGVLNDDNTKGAINVRKVIIAQAIGGIFFSLFGGQPMIILLTTVPLAIYIKVIFKISQELGYDFLAMYACVGLFCQMFLILYSATELCSLMKFATRSAEEMFSLFIAIAFTVESIRAIHNSFKKNYNDCDTSAISMKAARTALNAFKNGSNADSIVGNI------TSSMSIGDTGSLCRRDTSILYMLLMFGTLWLGLFLYNFRKTPYLTRSRREWLADYALPASVLIMSFTGSYAFSDIEKDRFNLRFEFPLIQMADVTSLPPSGYFVCLLLGFSLSFLFFIDQNITSAIVNNNQNKLKKGTSHNLDLFVVALLNMFLSVFGLPWMHGALPHSPLHLRALADVEERVSQG-HVHEVIMNVRETRLASLIAHVMILVSMFFLIPYPLQLIPTSVLHGLFLYMALTSLSGNEMFERLLLLITEQQAYPPTHYIRKVPQRKVHLFTACQLLQLIILCAFGFSPYPFIEMVFPIVCFFFLPIRHTLIPRLIDYKYLDALD 875
BLAST of slc4a-8 vs. Ensembl Celegans
Match: abts-3 (Anion/Bicarbonate TranSporter family [Source:UniProtKB/TrEMBL;Acc:A0A3B1E4W4]) HSP 1 Score: 668.307 bits (1723), Expect = 0.000e+0 Identity = 362/782 (46.29%), Postives = 524/782 (67.01%), Query Frame = 2
Query: 530 LFLSRLEKIPMKDFSAEVRATLDIQKFLKEAVLLLDMSGSCLEEIIDSMLLTILANEVTDAKVSLEALVEEAKKTLFIQSSYLTYTYQRLAKTIRGLSLSETEG--LMTDQSWLCTMCSLNCIHKRHVAIARLNNPVNMGRSSEGIYFIILVVTPTKEKGTKSDIELGRTFATIFADVEFRQQLLFSESVEQFKELLQYHSGDLMEDQAM--NRRKSLKVQEVMNQAFHFDKKYLVGSGIVSDFKKRFPVYLMDFRDGFRGKGTIRKVISATIFLYFACLLPSIAFGVLNYNNTEGKIDVRRVIISQAIGGLCFGFFSGQXXXXXXXXXXXXXFVKIISSICNDYDLDFFAMYSCVGLINSLLLILYAMFDISKLMRWSTRSSEEIFALFVAISFVVDAVKDIYKEFSTHYFSCYLSANNQSTEHLRLSRFKRAFSG--IISNIXXXXXXXXXXXXXXXXXXCQREVSILYLFLVAGTVWLAIQLFTSTKTPFLNNAKREMLTDFALPLAVVIMSLIGTYLFKEIEMQPFVIVEEKVKFEASGILKLPWLAIAGAIALAFPLSLLMFMDQNISSAMVNSPANKLKKGSSYHWDLLVVALINAGLSVFGLPLVHGALPHSPLHVKALADLEERIDTAHHVHQTIVKVRETRITSILSHVFIGISLQML-PIPLIYIPVAVLDGLFVYMAVTTLYGNQFFERILLLFTEQSAYPPSHYLRRVPQRKLHIFTGLQIFQLAGLCLLGFSPSPYLKMGFPLLLLFHMVFRHQVVPRVIDEKYLNALD 2854
L ++ EKIPMKDF +E+RAT+DI L +AVLLLD+ + LEEI ++ + E E E+ + LF Q + + L++T++ + + + G DQ+W+C +C LN + RHVAIARL++P N+GR+ + + FII+V+ P++ KGTK+ +E RTFAT+FAD+E RQ+L+ ++SVEQF+ L + +L DQ R+ S+ + Q F + Y G+V +FK+R +Y D+ DG RG T++K+ S +FLYFACLLP+IAFGVLN +NT+G I+VR+VII+QAIGG+ F F GQP+IILLTT PLA+++K+I I + DF AMY+CVGL + LILY+ ++ LM+++TRS+EE+F+LF+AI+F V++++ I+ F +Y C SA + L+ FK + I+ NI T+ S + + C+R+ SILY+ L+ GT+WL + L+ KTP+L ++RE L D+ALP +V+IMS G+Y F +IE F + E + + + LP + L F LS L F+DQNI+SA+VN+ NKLKKG+S++ DL VVAL+N LSVFGLP +HGALPHSPLH++ALAD+EER+ HVH+ I+ VRETR+ S+++HV I +S+ L P PL IP +VL GLF+YMA+T+L GN+ FER+LLL TEQ AYPP+HY+R+VPQRK+H+FT Q+ QL LC GFSP P+++M FP++ F + RH ++PR+ID KYL+ALD
Sbjct: 30 LMYAKHEKIPMKDFGSEIRATMDIDHLLNKAVLLLDLQETSLEEIFAKIIHEMDIQEP-------EFTSEQVRSVLFTQDA--GNQFHILSRTVQSICTTGSVGGSFDYDQTWICALCMLNTVQHRHVAIARLSHPTNLGRTMQDLRFIIIVIAPSRAKGTKTALETTRTFATLFADMEIRQRLVMAQSVEQFRSTLLSAAKELAMDQNQWRERKSSIHLSHAKEQIFGPEAWYPF-RGLVEEFKRRLAIYPSDYLDGIRGHKTVQKLFSTVVFLYFACLLPAIAFGVLNDDNTKGAINVRKVIIAQAIGGIFFSLFGGQPMIILLTTVPLAIYIKVIFKISQELGYDFLAMYACVGLFCQMFLILYSATELCSLMKFATRSAEEMFSLFIAIAFTVESIRAIHNSFKKNYNDCDTSAISMKAARTALNAFKNGSNADSIVGNI------TSSMSIGDTGSLCRRDTSILYMLLMFGTLWLGLFLYNFRKTPYLTRSRREWLADYALPASVLIMSFTGSYAFSDIEKDRFNLRFEFPLIQMADVTSLPPSGYFVCLLLGFSLSFLFFIDQNITSAIVNNNQNKLKKGTSHNLDLFVVALLNMFLSVFGLPWMHGALPHSPLHLRALADVEERVSQG-HVHEVIMNVRETRLASLIAHVMILVSMFFLIPYPLQLIPTSVLHGLFLYMALTSLSGNEMFERLLLLITEQQAYPPTHYIRKVPQRKVHLFTACQLLQLIILCAFGFSPYPFIEMVFPIVCFFFLPIRHTLIPRLIDYKYLDALD 794
BLAST of slc4a-8 vs. Ensembl Celegans
Match: abts-3 (Anion/Bicarbonate TranSporter family [Source:UniProtKB/TrEMBL;Acc:A0A3B1E4W4]) HSP 1 Score: 667.922 bits (1722), Expect = 0.000e+0 Identity = 362/782 (46.29%), Postives = 524/782 (67.01%), Query Frame = 2
Query: 530 LFLSRLEKIPMKDFSAEVRATLDIQKFLKEAVLLLDMSGSCLEEIIDSMLLTILANEVTDAKVSLEALVEEAKKTLFIQSSYLTYTYQRLAKTIRGLSLSETEG--LMTDQSWLCTMCSLNCIHKRHVAIARLNNPVNMGRSSEGIYFIILVVTPTKEKGTKSDIELGRTFATIFADVEFRQQLLFSESVEQFKELLQYHSGDLMEDQAM--NRRKSLKVQEVMNQAFHFDKKYLVGSGIVSDFKKRFPVYLMDFRDGFRGKGTIRKVISATIFLYFACLLPSIAFGVLNYNNTEGKIDVRRVIISQAIGGLCFGFFSGQXXXXXXXXXXXXXFVKIISSICNDYDLDFFAMYSCVGLINSLLLILYAMFDISKLMRWSTRSSEEIFALFVAISFVVDAVKDIYKEFSTHYFSCYLSANNQSTEHLRLSRFKRAFSG--IISNIXXXXXXXXXXXXXXXXXXCQREVSILYLFLVAGTVWLAIQLFTSTKTPFLNNAKREMLTDFALPLAVVIMSLIGTYLFKEIEMQPFVIVEEKVKFEASGILKLPWLAIAGAIALAFPLSLLMFMDQNISSAMVNSPANKLKKGSSYHWDLLVVALINAGLSVFGLPLVHGALPHSPLHVKALADLEERIDTAHHVHQTIVKVRETRITSILSHVFIGISLQML-PIPLIYIPVAVLDGLFVYMAVTTLYGNQFFERILLLFTEQSAYPPSHYLRRVPQRKLHIFTGLQIFQLAGLCLLGFSPSPYLKMGFPLLLLFHMVFRHQVVPRVIDEKYLNALD 2854
L ++ EKIPMKDF +E+RAT+DI L +AVLLLD+ + LEEI ++ + E E E+ + LF Q + + L++T++ + + + G DQ+W+C +C LN + RHVAIARL++P N+GR+ + + FII+V+ P++ KGTK+ +E RTFAT+FAD+E RQ+L+ ++SVEQF+ L + +L DQ R+ S+ + Q F + Y G+V +FK+R +Y D+ DG RG T++K+ S +FLYFACLLP+IAFGVLN +NT+G I+VR+VII+QAIGG+ F F GQP+IILLTT PLA+++K+I I + DF AMY+CVGL + LILY+ ++ LM+++TRS+EE+F+LF+AI+F V++++ I+ F +Y C SA + L+ FK + I+ NI T+ S + + C+R+ SILY+ L+ GT+WL + L+ KTP+L ++RE L D+ALP +V+IMS G+Y F +IE F + E + + + LP + L F LS L F+DQNI+SA+VN+ NKLKKG+S++ DL VVAL+N LSVFGLP +HGALPHSPLH++ALAD+EER+ HVH+ I+ VRETR+ S+++HV I +S+ L P PL IP +VL GLF+YMA+T+L GN+ FER+LLL TEQ AYPP+HY+R+VPQRK+H+FT Q+ QL LC GFSP P+++M FP++ F + RH ++PR+ID KYL+ALD
Sbjct: 123 LMYAKHEKIPMKDFGSEIRATMDIDHLLNKAVLLLDLQETSLEEIFAKIIHEMDIQEP-------EFTSEQVRSVLFTQDA--GNQFHILSRTVQSICTTGSVGGSFDYDQTWICALCMLNTVQHRHVAIARLSHPTNLGRTMQDLRFIIIVIAPSRAKGTKTALETTRTFATLFADMEIRQRLVMAQSVEQFRSTLLSAAKELAMDQNQWRERKSSIHLSHAKEQIFGPEAWYPF-RGLVEEFKRRLAIYPSDYLDGIRGHKTVQKLFSTVVFLYFACLLPAIAFGVLNDDNTKGAINVRKVIIAQAIGGIFFSLFGGQPMIILLTTVPLAIYIKVIFKISQELGYDFLAMYACVGLFCQMFLILYSATELCSLMKFATRSAEEMFSLFIAIAFTVESIRAIHNSFKKNYNDCDTSAISMKAARTALNAFKNGSNADSIVGNI------TSSMSIGDTGSLCRRDTSILYMLLMFGTLWLGLFLYNFRKTPYLTRSRREWLADYALPASVLIMSFTGSYAFSDIEKDRFNLRFEFPLIQMADVTSLPPSGYFVCLLLGFSLSFLFFIDQNITSAIVNNNQNKLKKGTSHNLDLFVVALLNMFLSVFGLPWMHGALPHSPLHLRALADVEERVSQG-HVHEVIMNVRETRLASLIAHVMILVSMFFLIPYPLQLIPTSVLHGLFLYMALTSLSGNEMFERLLLLITEQQAYPPTHYIRKVPQRKVHLFTACQLLQLIILCAFGFSPYPFIEMVFPIVCFFFLPIRHTLIPRLIDYKYLDALD 887
BLAST of slc4a-8 vs. Ensembl Fly
Match: Ndae1 (gene:FBgn0259111 transcript:FBtr0299537) HSP 1 Score: 191.045 bits (484), Expect = 1.898e-49 Identity = 170/559 (30.41%), Postives = 272/559 (48.66%), Query Frame = 2
Query: 1229 SGIVSDFKKRFPVYLMDFRDGFRGKGTIRKVISATIFLYFACLLPSIAFGVLNYNNTEGKIDVRRVIISQAIGGLCFGFFSGQXXXXXXXXXXXXXFVKIISSICNDYDLDFFAMYSCVGLINSLLLILYAMFDISKLMRWSTRSSEEIFALFVAISFVVDAVKD---IYKEFSTHY--FSCYLSANNQSTEHLRLSRFKRAFSGIISNIXXXXXXXXXXXXXXXXXXC----QREVSILYLFLVAGTVWLAIQLFTSTKTPFLNNAKREMLTDFALPLAVVIMSLIGTYLFKEIEMQPFVIVEE-KVKFEASGIL------KLPWLAIAGAIALAFPLSLLMFMDQNISSAMVNSPANKLKKGSSYHWDLLVVALINAGLSVFGLPLVHGALPHSPLHVKALADLEERIDTAHHVHQTIVKVRETRITSILSHVFIGISLQMLPIPLIYIPVAVLDGLFVYMAVTTLYGNQFFERILLLFTEQSAYPPSHYLRRVPQRKLHIFTGLQIFQLAGLCLL-GFSPSPYLKMGFPLLLLFHMVFRHQVVPRVIDEKYLNALD 2854
G+++D K++ P Y+ D++D + +++ IFLYFACL P I FG L T + ++S + G+ +GFFSGQPL IL +T P+ +F II C D+ +G+ + + I+ D S L+ + TR +EE FA +A F+ A+++ I K F + + C + S + +I + + C V ++ + L AGT ++ L F + R+ ++DF++ +A+ MS L + Q + E K G L K PW + A+ A ++L+FMDQ I++ +VN NKLKKG YH DL +++++ A S+ GLP A S HV +L LE Q + VRE R+T IL + IG+S+ + P+ L IP+ VL G+F+YM V +L G QFF+RIL++F P +LR+VP +++H+FT +Q+ L L L+ FS + L FPL+L+ + R + + V + L LD
Sbjct: 415 GGLINDIKRKAPWYISDYKDALS-----MQCVASWIFLYFACLSPIITFGGLLAEATGKHMAAMESLVSGFVCGMGYGFFSGQPLTILGSTGPVLVFESIIYEFCLKMGWDYMTFRFWIGMWVAGICIVLTAIDASALVCYITRFTEENFATLIAFIFIYKAIENVMVIGKNFPVNQGIYDCVCTPPIGSN------------ASVIDYAKYNWDSCESYNGTLVGGDCGTPPTENVFLMSVVLCAGTFLISTVLKEFKNALFFPSIVRQYISDFSVLIAIFAMSFFDYSL--GVPTQKLEVPNELKPTLSTRGWLIPPFVEKNPWWSAIIAVFPALLGTILIFMDQQITAVIVNRKENKLKKGCGYHLDLFILSILIAICSMMGLPWFVAATVLSINHVNSLK-LESECSAPGEKPQ-FLGVREQRVTHILIFLTIGVSVLLTPL-LGNIPMPVLFGVFLYMGVASLKGLQFFDRILIMFMPAKYQPDYMFLRQVPIKRVHLFTMIQLACLIILWLIKSFSQTSIL---FPLMLVVMIGIR-KALDLVFTRRELKILD 947
BLAST of slc4a-8 vs. Ensembl Fly
Match: Ndae1 (gene:FBgn0259111 transcript:FBtr0331660) HSP 1 Score: 190.66 bits (483), Expect = 2.091e-49 Identity = 170/559 (30.41%), Postives = 272/559 (48.66%), Query Frame = 2
Query: 1229 SGIVSDFKKRFPVYLMDFRDGFRGKGTIRKVISATIFLYFACLLPSIAFGVLNYNNTEGKIDVRRVIISQAIGGLCFGFFSGQXXXXXXXXXXXXXFVKIISSICNDYDLDFFAMYSCVGLINSLLLILYAMFDISKLMRWSTRSSEEIFALFVAISFVVDAVKD---IYKEFSTHY--FSCYLSANNQSTEHLRLSRFKRAFSGIISNIXXXXXXXXXXXXXXXXXXC----QREVSILYLFLVAGTVWLAIQLFTSTKTPFLNNAKREMLTDFALPLAVVIMSLIGTYLFKEIEMQPFVIVEE-KVKFEASGIL------KLPWLAIAGAIALAFPLSLLMFMDQNISSAMVNSPANKLKKGSSYHWDLLVVALINAGLSVFGLPLVHGALPHSPLHVKALADLEERIDTAHHVHQTIVKVRETRITSILSHVFIGISLQMLPIPLIYIPVAVLDGLFVYMAVTTLYGNQFFERILLLFTEQSAYPPSHYLRRVPQRKLHIFTGLQIFQLAGLCLL-GFSPSPYLKMGFPLLLLFHMVFRHQVVPRVIDEKYLNALD 2854
G+++D K++ P Y+ D++D + +++ IFLYFACL P I FG L T + ++S + G+ +GFFSGQPL IL +T P+ +F II C D+ +G+ + + I+ D S L+ + TR +EE FA +A F+ A+++ I K F + + C + S + +I + + C V ++ + L AGT ++ L F + R+ ++DF++ +A+ MS L + Q + E K G L K PW + A+ A ++L+FMDQ I++ +VN NKLKKG YH DL +++++ A S+ GLP A S HV +L LE Q + VRE R+T IL + IG+S+ + P+ L IP+ VL G+F+YM V +L G QFF+RIL++F P +LR+VP +++H+FT +Q+ L L L+ FS + L FPL+L+ + R + + V + L LD
Sbjct: 412 GGLINDIKRKAPWYISDYKDALS-----MQCVASWIFLYFACLSPIITFGGLLAEATGKHMAAMESLVSGFVCGMGYGFFSGQPLTILGSTGPVLVFESIIYEFCLKMGWDYMTFRFWIGMWVAGICIVLTAIDASALVCYITRFTEENFATLIAFIFIYKAIENVMVIGKNFPVNQGIYDCVCTPPIGSN------------ASVIDYAKYNWDSCESYNGTLVGGDCGTPPTENVFLMSVVLCAGTFLISTVLKEFKNALFFPSIVRQYISDFSVLIAIFAMSFFDYSL--GVPTQKLEVPNELKPTLSTRGWLIPPFVEKNPWWSAIIAVFPALLGTILIFMDQQITAVIVNRKENKLKKGCGYHLDLFILSILIAICSMMGLPWFVAATVLSINHVNSLK-LESECSAPGEKPQ-FLGVREQRVTHILIFLTIGVSVLLTPL-LGNIPMPVLFGVFLYMGVASLKGLQFFDRILIMFMPAKYQPDYMFLRQVPIKRVHLFTMIQLACLIILWLIKSFSQTSIL---FPLMLVVMIGIR-KALDLVFTRRELKILD 944
BLAST of slc4a-8 vs. Ensembl Fly
Match: Ndae1 (gene:FBgn0259111 transcript:FBtr0331662) HSP 1 Score: 190.66 bits (483), Expect = 2.555e-49 Identity = 170/559 (30.41%), Postives = 272/559 (48.66%), Query Frame = 2
Query: 1229 SGIVSDFKKRFPVYLMDFRDGFRGKGTIRKVISATIFLYFACLLPSIAFGVLNYNNTEGKIDVRRVIISQAIGGLCFGFFSGQXXXXXXXXXXXXXFVKIISSICNDYDLDFFAMYSCVGLINSLLLILYAMFDISKLMRWSTRSSEEIFALFVAISFVVDAVKD---IYKEFSTHY--FSCYLSANNQSTEHLRLSRFKRAFSGIISNIXXXXXXXXXXXXXXXXXXC----QREVSILYLFLVAGTVWLAIQLFTSTKTPFLNNAKREMLTDFALPLAVVIMSLIGTYLFKEIEMQPFVIVEE-KVKFEASGIL------KLPWLAIAGAIALAFPLSLLMFMDQNISSAMVNSPANKLKKGSSYHWDLLVVALINAGLSVFGLPLVHGALPHSPLHVKALADLEERIDTAHHVHQTIVKVRETRITSILSHVFIGISLQMLPIPLIYIPVAVLDGLFVYMAVTTLYGNQFFERILLLFTEQSAYPPSHYLRRVPQRKLHIFTGLQIFQLAGLCLL-GFSPSPYLKMGFPLLLLFHMVFRHQVVPRVIDEKYLNALD 2854
G+++D K++ P Y+ D++D + +++ IFLYFACL P I FG L T + ++S + G+ +GFFSGQPL IL +T P+ +F II C D+ +G+ + + I+ D S L+ + TR +EE FA +A F+ A+++ I K F + + C + S + +I + + C V ++ + L AGT ++ L F + R+ ++DF++ +A+ MS L + Q + E K G L K PW + A+ A ++L+FMDQ I++ +VN NKLKKG YH DL +++++ A S+ GLP A S HV +L LE Q + VRE R+T IL + IG+S+ + P+ L IP+ VL G+F+YM V +L G QFF+RIL++F P +LR+VP +++H+FT +Q+ L L L+ FS + L FPL+L+ + R + + V + L LD
Sbjct: 438 GGLINDIKRKAPWYISDYKDALS-----MQCVASWIFLYFACLSPIITFGGLLAEATGKHMAAMESLVSGFVCGMGYGFFSGQPLTILGSTGPVLVFESIIYEFCLKMGWDYMTFRFWIGMWVAGICIVLTAIDASALVCYITRFTEENFATLIAFIFIYKAIENVMVIGKNFPVNQGIYDCVCTPPIGSN------------ASVIDYAKYNWDSCESYNGTLVGGDCGTPPTENVFLMSVVLCAGTFLISTVLKEFKNALFFPSIVRQYISDFSVLIAIFAMSFFDYSL--GVPTQKLEVPNELKPTLSTRGWLIPPFVEKNPWWSAIIAVFPALLGTILIFMDQQITAVIVNRKENKLKKGCGYHLDLFILSILIAICSMMGLPWFVAATVLSINHVNSLK-LESECSAPGEKPQ-FLGVREQRVTHILIFLTIGVSVLLTPL-LGNIPMPVLFGVFLYMGVASLKGLQFFDRILIMFMPAKYQPDYMFLRQVPIKRVHLFTMIQLACLIILWLIKSFSQTSIL---FPLMLVVMIGIR-KALDLVFTRRELKILD 970
BLAST of slc4a-8 vs. Ensembl Fly
Match: Ndae1 (gene:FBgn0259111 transcript:FBtr0331659) HSP 1 Score: 190.66 bits (483), Expect = 2.778e-49 Identity = 170/559 (30.41%), Postives = 272/559 (48.66%), Query Frame = 2
Query: 1229 SGIVSDFKKRFPVYLMDFRDGFRGKGTIRKVISATIFLYFACLLPSIAFGVLNYNNTEGKIDVRRVIISQAIGGLCFGFFSGQXXXXXXXXXXXXXFVKIISSICNDYDLDFFAMYSCVGLINSLLLILYAMFDISKLMRWSTRSSEEIFALFVAISFVVDAVKD---IYKEFSTHY--FSCYLSANNQSTEHLRLSRFKRAFSGIISNIXXXXXXXXXXXXXXXXXXC----QREVSILYLFLVAGTVWLAIQLFTSTKTPFLNNAKREMLTDFALPLAVVIMSLIGTYLFKEIEMQPFVIVEE-KVKFEASGIL------KLPWLAIAGAIALAFPLSLLMFMDQNISSAMVNSPANKLKKGSSYHWDLLVVALINAGLSVFGLPLVHGALPHSPLHVKALADLEERIDTAHHVHQTIVKVRETRITSILSHVFIGISLQMLPIPLIYIPVAVLDGLFVYMAVTTLYGNQFFERILLLFTEQSAYPPSHYLRRVPQRKLHIFTGLQIFQLAGLCLL-GFSPSPYLKMGFPLLLLFHMVFRHQVVPRVIDEKYLNALD 2854
G+++D K++ P Y+ D++D + +++ IFLYFACL P I FG L T + ++S + G+ +GFFSGQPL IL +T P+ +F II C D+ +G+ + + I+ D S L+ + TR +EE FA +A F+ A+++ I K F + + C + S + +I + + C V ++ + L AGT ++ L F + R+ ++DF++ +A+ MS L + Q + E K G L K PW + A+ A ++L+FMDQ I++ +VN NKLKKG YH DL +++++ A S+ GLP A S HV +L LE Q + VRE R+T IL + IG+S+ + P+ L IP+ VL G+F+YM V +L G QFF+RIL++F P +LR+VP +++H+FT +Q+ L L L+ FS + L FPL+L+ + R + + V + L LD
Sbjct: 471 GGLINDIKRKAPWYISDYKDALS-----MQCVASWIFLYFACLSPIITFGGLLAEATGKHMAAMESLVSGFVCGMGYGFFSGQPLTILGSTGPVLVFESIIYEFCLKMGWDYMTFRFWIGMWVAGICIVLTAIDASALVCYITRFTEENFATLIAFIFIYKAIENVMVIGKNFPVNQGIYDCVCTPPIGSN------------ASVIDYAKYNWDSCESYNGTLVGGDCGTPPTENVFLMSVVLCAGTFLISTVLKEFKNALFFPSIVRQYISDFSVLIAIFAMSFFDYSL--GVPTQKLEVPNELKPTLSTRGWLIPPFVEKNPWWSAIIAVFPALLGTILIFMDQQITAVIVNRKENKLKKGCGYHLDLFILSILIAICSMMGLPWFVAATVLSINHVNSLK-LESECSAPGEKPQ-FLGVREQRVTHILIFLTIGVSVLLTPL-LGNIPMPVLFGVFLYMGVASLKGLQFFDRILIMFMPAKYQPDYMFLRQVPIKRVHLFTMIQLACLIILWLIKSFSQTSIL---FPLMLVVMIGIR-KALDLVFTRRELKILD 1003
BLAST of slc4a-8 vs. Ensembl Fly
Match: Ndae1 (gene:FBgn0259111 transcript:FBtr0299538) HSP 1 Score: 190.66 bits (483), Expect = 2.938e-49 Identity = 170/559 (30.41%), Postives = 272/559 (48.66%), Query Frame = 2
Query: 1229 SGIVSDFKKRFPVYLMDFRDGFRGKGTIRKVISATIFLYFACLLPSIAFGVLNYNNTEGKIDVRRVIISQAIGGLCFGFFSGQXXXXXXXXXXXXXFVKIISSICNDYDLDFFAMYSCVGLINSLLLILYAMFDISKLMRWSTRSSEEIFALFVAISFVVDAVKD---IYKEFSTHY--FSCYLSANNQSTEHLRLSRFKRAFSGIISNIXXXXXXXXXXXXXXXXXXC----QREVSILYLFLVAGTVWLAIQLFTSTKTPFLNNAKREMLTDFALPLAVVIMSLIGTYLFKEIEMQPFVIVEE-KVKFEASGIL------KLPWLAIAGAIALAFPLSLLMFMDQNISSAMVNSPANKLKKGSSYHWDLLVVALINAGLSVFGLPLVHGALPHSPLHVKALADLEERIDTAHHVHQTIVKVRETRITSILSHVFIGISLQMLPIPLIYIPVAVLDGLFVYMAVTTLYGNQFFERILLLFTEQSAYPPSHYLRRVPQRKLHIFTGLQIFQLAGLCLL-GFSPSPYLKMGFPLLLLFHMVFRHQVVPRVIDEKYLNALD 2854
G+++D K++ P Y+ D++D + +++ IFLYFACL P I FG L T + ++S + G+ +GFFSGQPL IL +T P+ +F II C D+ +G+ + + I+ D S L+ + TR +EE FA +A F+ A+++ I K F + + C + S + +I + + C V ++ + L AGT ++ L F + R+ ++DF++ +A+ MS L + Q + E K G L K PW + A+ A ++L+FMDQ I++ +VN NKLKKG YH DL +++++ A S+ GLP A S HV +L LE Q + VRE R+T IL + IG+S+ + P+ L IP+ VL G+F+YM V +L G QFF+RIL++F P +LR+VP +++H+FT +Q+ L L L+ FS + L FPL+L+ + R + + V + L LD
Sbjct: 484 GGLINDIKRKAPWYISDYKDALS-----MQCVASWIFLYFACLSPIITFGGLLAEATGKHMAAMESLVSGFVCGMGYGFFSGQPLTILGSTGPVLVFESIIYEFCLKMGWDYMTFRFWIGMWVAGICIVLTAIDASALVCYITRFTEENFATLIAFIFIYKAIENVMVIGKNFPVNQGIYDCVCTPPIGSN------------ASVIDYAKYNWDSCESYNGTLVGGDCGTPPTENVFLMSVVLCAGTFLISTVLKEFKNALFFPSIVRQYISDFSVLIAIFAMSFFDYSL--GVPTQKLEVPNELKPTLSTRGWLIPPFVEKNPWWSAIIAVFPALLGTILIFMDQQITAVIVNRKENKLKKGCGYHLDLFILSILIAICSMMGLPWFVAATVLSINHVNSLK-LESECSAPGEKPQ-FLGVREQRVTHILIFLTIGVSVLLTPL-LGNIPMPVLFGVFLYMGVASLKGLQFFDRILIMFMPAKYQPDYMFLRQVPIKRVHLFTMIQLACLIILWLIKSFSQTSIL---FPLMLVVMIGIR-KALDLVFTRRELKILD 1016
BLAST of slc4a-8 vs. Ensembl Zebrafish
Match: slc4a11 (solute carrier family 4 member 11 [Source:ZFIN;Acc:ZDB-GENE-090313-183]) HSP 1 Score: 539.265 bits (1388), Expect = 2.945e-178 Identity = 319/788 (40.48%), Postives = 497/788 (63.07%), Query Frame = 2
Query: 527 CLFLSRLEKIPMKDFSAEVRATLDIQKFLKEAVLLLDMSGSCLEEIIDSMLLTILANEVTDAKVSLEALVEEAKKTLFIQSSYLTYTYQRLAKTIRGLSLSETEGLMTDQSWLCTMCSLNCIHKRHVAIARLNNPVNMGRSSEGIYFIILVVTPTKEKGTKSDIELGRTFATIFADVEFRQQLLFSESVEQFKELL---QYH--------SGDLMEDQAMNRRKSLKVQEVMNQAFHFDKKYLVGSGIVSDFKKRFPVYLMDFRDGFRGKG-TIRKVISATIFLYFACLLPSIAFGVLNYNNTEGKIDVRRVIISQAIGGLCFGFFSGQXXXXXXXXXXXXXFVKIISSICNDYDLDFFAMYSCVGLINSLLLILYAMFDISKLMRWSTRSSEEIFALFVAISFVVDAVKDIYKEFSTHYFSCYLSANNQSTEHLRLSRFKRAFSGIISNIXXXXXXXXXXXXXXXXXXCQREVSILYLFLVAGTVWLAIQLFTSTKTPFLNNAKREMLTDFALPLAVVIMSLIGTYLFKEIEMQPFVIVEEKVKFEASGILKLPWLAIAGAIALAFPLSLLMFMDQNISSAMVNSPANKLKKGSSYHWDLLVVALINAGLSVFGLPLVHGALPHSPLHVKALADLEERIDTAHHVHQTIVKVRETRITSILSHVFIGISLQMLPIPLIYIPVAVLDGLFVYMAVTTLYGNQFFERILLLFTEQSAYPPSHYLRRVPQRKLHIFTGLQIFQLAGLCLLGFSPSPYLKMGFPLLLLFHMVFRHQVVPRVIDEKYLNALD 2854
C+F S + + +F EVRA D+ FL+ A +LL + L++++ +ML + + T EE +LF + L++T++ ++ + T G+ QSWLC +C++ + +RHV I+RL+ P N G + + ++IL++ P+K K TK+ +ELGRTFA++F+D+ FRQ+LL S++ E+FKE L +YH + E+ + +K LK ++ + VG GI D +R P+Y DF DG G + K ++ +IFLY A LLP+IAFG LN +T G+IDV++ II Q+IGG+ + +G PL+I LTTAP+A+F+ +I IC+DY+LDF A Y+C+GL NSL LI+ +F++S L++ RS EE+ ALF++I+FV DAVK K F +Y + L AN + E R+S G + ++ T+ S S C R +L L L+ GT+W+ L+ ++PFL+ RE+L+D ALP++V++ S +G+Y+F +I + F E V F+ + + KL ++ A+ L F L LL+F+DQNI ++ N+P N+L KG++YHWDL + LIN +SV GLP +H A PHS LHV+ LA +EER++ H +++TIV V+ETR+TS+++++ IG+S+ +LP+PL +IP VL GLF+Y+A+T++ GNQ +R+ LL EQ++YPP+HY+R+VPQRK+H FT LQ+ QL LC G P PY+KM FPLL+ + R+ ++PR+I+ KYL+ +D
Sbjct: 51 CVFASGFRYVKLMNFEEEVRAHRDLDGFLERASILLHEDEASLDDVLKTMLRHVSQDPHTAEP---GCNFEEIMSSLFTDAGSQEVNVHLLSETLQCVTATAT-GIQYQQSWLCILCNVKNLQRRHVCISRLDRPQNWGENCAEVRYVILILAPSKMKSTKTAMELGRTFASMFSDISFRQKLLESKTQEEFKEALVIQRYHLTAAKRKTTAVEGEETDPHSQKPLKCRDF----------FRVGRGIYEDLCRRLPLYPSDFTDGLVGNNKALVKFMTTSIFLYIAVLLPAIAFGSLNDESTRGEIDVQKTIIGQSIGGIIYSLCAGSPLVIPLTTAPIAIFISVIRGICDDYELDFAAFYACIGLWNSLFLIMGGVFNLSLLVKLFKRSIEEVIALFISIAFVADAVKGTVKIFHDNYHAPTL-ANGSAAELNRIS-------GSVHLGELNQTEAGPVSLPESFILCTRARPLLCLLLMMGTLWVGYTLYQFRRSPFLHVKMREILSDCALPISVLVFSYVGSYVFNDIALPVFNFHEGPV-FQVAPLDKLTGASVLSAMGLGFLLFLLIFIDQNIVVSLTNAPENRLLKGTAYHWDLTLSGLINILMSVLGLPWMHAAFPHSTLHVRQLAIVEERVEGGH-LYETIVSVKETRVTSLVANILIGVSVFLLPVPLQWIPKPVLYGLFLYIALTSIEGNQMCDRMALLLKEQTSYPPTHYIRKVPQRKIHYFTFLQMVQLLFLCAFGMYPLPYMKMIFPLLMFILIPIRNCLLPRIIEAKYLDIMD 814
BLAST of slc4a-8 vs. Ensembl Zebrafish
Match: slc4a11 (solute carrier family 4 member 11 [Source:ZFIN;Acc:ZDB-GENE-090313-183]) HSP 1 Score: 539.265 bits (1388), Expect = 2.945e-178 Identity = 319/788 (40.48%), Postives = 497/788 (63.07%), Query Frame = 2
Query: 527 CLFLSRLEKIPMKDFSAEVRATLDIQKFLKEAVLLLDMSGSCLEEIIDSMLLTILANEVTDAKVSLEALVEEAKKTLFIQSSYLTYTYQRLAKTIRGLSLSETEGLMTDQSWLCTMCSLNCIHKRHVAIARLNNPVNMGRSSEGIYFIILVVTPTKEKGTKSDIELGRTFATIFADVEFRQQLLFSESVEQFKELL---QYH--------SGDLMEDQAMNRRKSLKVQEVMNQAFHFDKKYLVGSGIVSDFKKRFPVYLMDFRDGFRGKG-TIRKVISATIFLYFACLLPSIAFGVLNYNNTEGKIDVRRVIISQAIGGLCFGFFSGQXXXXXXXXXXXXXFVKIISSICNDYDLDFFAMYSCVGLINSLLLILYAMFDISKLMRWSTRSSEEIFALFVAISFVVDAVKDIYKEFSTHYFSCYLSANNQSTEHLRLSRFKRAFSGIISNIXXXXXXXXXXXXXXXXXXCQREVSILYLFLVAGTVWLAIQLFTSTKTPFLNNAKREMLTDFALPLAVVIMSLIGTYLFKEIEMQPFVIVEEKVKFEASGILKLPWLAIAGAIALAFPLSLLMFMDQNISSAMVNSPANKLKKGSSYHWDLLVVALINAGLSVFGLPLVHGALPHSPLHVKALADLEERIDTAHHVHQTIVKVRETRITSILSHVFIGISLQMLPIPLIYIPVAVLDGLFVYMAVTTLYGNQFFERILLLFTEQSAYPPSHYLRRVPQRKLHIFTGLQIFQLAGLCLLGFSPSPYLKMGFPLLLLFHMVFRHQVVPRVIDEKYLNALD 2854
C+F S + + +F EVRA D+ FL+ A +LL + L++++ +ML + + T EE +LF + L++T++ ++ + T G+ QSWLC +C++ + +RHV I+RL+ P N G + + ++IL++ P+K K TK+ +ELGRTFA++F+D+ FRQ+LL S++ E+FKE L +YH + E+ + +K LK ++ + VG GI D +R P+Y DF DG G + K ++ +IFLY A LLP+IAFG LN +T G+IDV++ II Q+IGG+ + +G PL+I LTTAP+A+F+ +I IC+DY+LDF A Y+C+GL NSL LI+ +F++S L++ RS EE+ ALF++I+FV DAVK K F +Y + L AN + E R+S G + ++ T+ S S C R +L L L+ GT+W+ L+ ++PFL+ RE+L+D ALP++V++ S +G+Y+F +I + F E V F+ + + KL ++ A+ L F L LL+F+DQNI ++ N+P N+L KG++YHWDL + LIN +SV GLP +H A PHS LHV+ LA +EER++ H +++TIV V+ETR+TS+++++ IG+S+ +LP+PL +IP VL GLF+Y+A+T++ GNQ +R+ LL EQ++YPP+HY+R+VPQRK+H FT LQ+ QL LC G P PY+KM FPLL+ + R+ ++PR+I+ KYL+ +D
Sbjct: 51 CVFASGFRYVKLMNFEEEVRAHRDLDGFLERASILLHEDEASLDDVLKTMLRHVSQDPHTAEP---GCNFEEIMSSLFTDAGSQEVNVHLLSETLQCVTATAT-GIQYQQSWLCILCNVKNLQRRHVCISRLDRPQNWGENCAEVRYVILILAPSKMKSTKTAMELGRTFASMFSDISFRQKLLESKTQEEFKEALVIQRYHLTAAKRKTTAVEGEETDPHSQKPLKCRDF----------FRVGRGIYEDLCRRLPLYPSDFTDGLVGNNKALVKFMTTSIFLYIAVLLPAIAFGSLNDESTRGEIDVQKTIIGQSIGGIIYSLCAGSPLVIPLTTAPIAIFISVIRGICDDYELDFAAFYACIGLWNSLFLIMGGVFNLSLLVKLFKRSIEEVIALFISIAFVADAVKGTVKIFHDNYHAPTL-ANGSAAELNRIS-------GSVHLGELNQTEAGPVSLPESFILCTRARPLLCLLLMMGTLWVGYTLYQFRRSPFLHVKMREILSDCALPISVLVFSYVGSYVFNDIALPVFNFHEGPV-FQVAPLDKLTGASVLSAMGLGFLLFLLIFIDQNIVVSLTNAPENRLLKGTAYHWDLTLSGLINILMSVLGLPWMHAAFPHSTLHVRQLAIVEERVEGGH-LYETIVSVKETRVTSLVANILIGVSVFLLPVPLQWIPKPVLYGLFLYIALTSIEGNQMCDRMALLLKEQTSYPPTHYIRKVPQRKIHYFTFLQMVQLLFLCAFGMYPLPYMKMIFPLLMFILIPIRNCLLPRIIEAKYLDIMD 814
BLAST of slc4a-8 vs. Ensembl Zebrafish
Match: slc4a11 (solute carrier family 4 member 11 [Source:ZFIN;Acc:ZDB-GENE-090313-183]) HSP 1 Score: 535.798 bits (1379), Expect = 2.137e-177 Identity = 320/795 (40.25%), Postives = 500/795 (62.89%), Query Frame = 2
Query: 509 EDDSVPCLFLSRLEK-IPMKDFSAEVRATLDIQKFLKEAVLLLDMSGSCLEEIIDSMLLTILANEVTDAKVSLEALVEEAKKTLFIQSSYLTYTYQRLAKTIRGLSLSETEGLMTDQSWLCTMCSLNCIHKRHVAIARLNNPVNMGRSSEGIYFIILVVTPTKEKGTKSDIELGRTFATIFADVEFRQQLLFSESVEQFKELL---QYH--------SGDLMEDQAMNRRKSLKVQEVMNQAFHFDKKYLVGSGIVSDFKKRFPVYLMDFRDGFRGKG-TIRKVISATIFLYFACLLPSIAFGVLNYNNTEGKIDVRRVIISQAIGGLCFGFFSGQXXXXXXXXXXXXXFVKIISSICNDYDLDFFAMYSCVGLINSLLLILYAMFDISKLMRWSTRSSEEIFALFVAISFVVDAVKDIYKEFSTHYFSCYLSANNQSTEHLRLSRFKRAFSGIISNIXXXXXXXXXXXXXXXXXXCQREVSILYLFLVAGTVWLAIQLFTSTKTPFLNNAKREMLTDFALPLAVVIMSLIGTYLFKEIEMQPFVIVEEKVKFEASGILKLPWLAIAGAIALAFPLSLLMFMDQNISSAMVNSPANKLKKGSSYHWDLLVVALINAGLSVFGLPLVHGALPHSPLHVKALADLEERIDTAHHVHQTIVKVRETRITSILSHVFIGISLQMLPIPLIYIPVAVLDGLFVYMAVTTLYGNQFFERILLLFTEQSAYPPSHYLRRVPQRKLHIFTGLQIFQLAGLCLLGFSPSPYLKMGFPLLLLFHMVFRHQVVPRVIDEKYLNALD 2854
E D C+ L+ + + + +F EVRA D+ FL+ A +LL + L++++ +ML + + T EE +LF + L++T++ ++ + T G+ QSWLC +C++ + +RHV I+RL+ P N G + + ++IL++ P+K K TK+ +ELGRTFA++F+D+ FRQ+LL S++ E+FKE L +YH + E+ + +K LK ++ + VG GI D +R P+Y DF DG G + K ++ +IFLY A LLP+IAFG LN +T G+IDV++ II Q+IGG+ + +G PL+I LTTAP+A+F+ +I IC+DY+LDF A Y+C+GL NSL LI+ +F++S L++ RS EE+ ALF++I+FV DAVK K F +Y + L AN + E R+S G + ++ T+ S S C R +L L L+ GT+W+ L+ ++PFL+ RE+L+D ALP++V++ S +G+Y+F +I + F E V F+ + + KL ++ A+ L F L LL+F+DQNI ++ N+P N+L KG++YHWDL + LIN +SV GLP +H A PHS LHV+ LA +EER++ H +++TIV V+ETR+TS+++++ IG+S+ +LP+PL +IP VL GLF+Y+A+T++ GNQ +R+ LL EQ++YPP+HY+R+VPQRK+H FT LQ+ QL LC G P PY+KM FPLL+ + R+ ++PR+I+ KYL+ +D
Sbjct: 8 ETDVHGCVLLNTSRRYVKLMNFEEEVRAHRDLDGFLERASILLHEDEASLDDVLKTMLRHVSQDPHTAEP---GCNFEEIMSSLFTDAGSQEVNVHLLSETLQCVTATAT-GIQYQQSWLCILCNVKNLQRRHVCISRLDRPQNWGENCAEVRYVILILAPSKMKSTKTAMELGRTFASMFSDISFRQKLLESKTQEEFKEALVIQRYHLTAAKRKTTAVEGEETDPHSQKPLKCRDF----------FRVGRGIYEDLCRRLPLYPSDFTDGLVGNNKALVKFMTTSIFLYIAVLLPAIAFGSLNDESTRGEIDVQKTIIGQSIGGIIYSLCAGSPLVIPLTTAPIAIFISVIRGICDDYELDFAAFYACIGLWNSLFLIMGGVFNLSLLVKLFKRSIEEVIALFISIAFVADAVKGTVKIFHDNYHAPTL-ANGSAAELNRIS-------GSVHLGELNQTEAGPVSLPESFILCTRARPLLCLLLMMGTLWVGYTLYQFRRSPFLHVKMREILSDCALPISVLVFSYVGSYVFNDIALPVFNFHEGPV-FQVAPLDKLTGASVLSAMGLGFLLFLLIFIDQNIVVSLTNAPENRLLKGTAYHWDLTLSGLINILMSVLGLPWMHAAFPHSTLHVRQLAIVEERVEGGH-LYETIVSVKETRVTSLVANILIGVSVFLLPVPLQWIPKPVLYGLFLYIALTSIEGNQMCDRMALLLKEQTSYPPTHYIRKVPQRKIHYFTFLQMVQLLFLCAFGMYPLPYMKMIFPLLMFILIPIRNCLLPRIIEAKYLDIMD 778
BLAST of slc4a-8 vs. Ensembl Zebrafish
Match: slc4a11 (solute carrier family 4 member 11 [Source:ZFIN;Acc:ZDB-GENE-090313-183]) HSP 1 Score: 535.798 bits (1379), Expect = 2.137e-177 Identity = 320/795 (40.25%), Postives = 500/795 (62.89%), Query Frame = 2
Query: 509 EDDSVPCLFLSRLEK-IPMKDFSAEVRATLDIQKFLKEAVLLLDMSGSCLEEIIDSMLLTILANEVTDAKVSLEALVEEAKKTLFIQSSYLTYTYQRLAKTIRGLSLSETEGLMTDQSWLCTMCSLNCIHKRHVAIARLNNPVNMGRSSEGIYFIILVVTPTKEKGTKSDIELGRTFATIFADVEFRQQLLFSESVEQFKELL---QYH--------SGDLMEDQAMNRRKSLKVQEVMNQAFHFDKKYLVGSGIVSDFKKRFPVYLMDFRDGFRGKG-TIRKVISATIFLYFACLLPSIAFGVLNYNNTEGKIDVRRVIISQAIGGLCFGFFSGQXXXXXXXXXXXXXFVKIISSICNDYDLDFFAMYSCVGLINSLLLILYAMFDISKLMRWSTRSSEEIFALFVAISFVVDAVKDIYKEFSTHYFSCYLSANNQSTEHLRLSRFKRAFSGIISNIXXXXXXXXXXXXXXXXXXCQREVSILYLFLVAGTVWLAIQLFTSTKTPFLNNAKREMLTDFALPLAVVIMSLIGTYLFKEIEMQPFVIVEEKVKFEASGILKLPWLAIAGAIALAFPLSLLMFMDQNISSAMVNSPANKLKKGSSYHWDLLVVALINAGLSVFGLPLVHGALPHSPLHVKALADLEERIDTAHHVHQTIVKVRETRITSILSHVFIGISLQMLPIPLIYIPVAVLDGLFVYMAVTTLYGNQFFERILLLFTEQSAYPPSHYLRRVPQRKLHIFTGLQIFQLAGLCLLGFSPSPYLKMGFPLLLLFHMVFRHQVVPRVIDEKYLNALD 2854
E D C+ L+ + + + +F EVRA D+ FL+ A +LL + L++++ +ML + + T EE +LF + L++T++ ++ + T G+ QSWLC +C++ + +RHV I+RL+ P N G + + ++IL++ P+K K TK+ +ELGRTFA++F+D+ FRQ+LL S++ E+FKE L +YH + E+ + +K LK ++ + VG GI D +R P+Y DF DG G + K ++ +IFLY A LLP+IAFG LN +T G+IDV++ II Q+IGG+ + +G PL+I LTTAP+A+F+ +I IC+DY+LDF A Y+C+GL NSL LI+ +F++S L++ RS EE+ ALF++I+FV DAVK K F +Y + L AN + E R+S G + ++ T+ S S C R +L L L+ GT+W+ L+ ++PFL+ RE+L+D ALP++V++ S +G+Y+F +I + F E V F+ + + KL ++ A+ L F L LL+F+DQNI ++ N+P N+L KG++YHWDL + LIN +SV GLP +H A PHS LHV+ LA +EER++ H +++TIV V+ETR+TS+++++ IG+S+ +LP+PL +IP VL GLF+Y+A+T++ GNQ +R+ LL EQ++YPP+HY+R+VPQRK+H FT LQ+ QL LC G P PY+KM FPLL+ + R+ ++PR+I+ KYL+ +D
Sbjct: 8 ETDVHGCVLLNTSRRYVKLMNFEEEVRAHRDLDGFLERASILLHEDEASLDDVLKTMLRHVSQDPHTAEP---GCNFEEIMSSLFTDAGSQEVNVHLLSETLQCVTATAT-GIQYQQSWLCILCNVKNLQRRHVCISRLDRPQNWGENCAEVRYVILILAPSKMKSTKTAMELGRTFASMFSDISFRQKLLESKTQEEFKEALVIQRYHLTAAKRKTTAVEGEETDPHSQKPLKCRDF----------FRVGRGIYEDLCRRLPLYPSDFTDGLVGNNKALVKFMTTSIFLYIAVLLPAIAFGSLNDESTRGEIDVQKTIIGQSIGGIIYSLCAGSPLVIPLTTAPIAIFISVIRGICDDYELDFAAFYACIGLWNSLFLIMGGVFNLSLLVKLFKRSIEEVIALFISIAFVADAVKGTVKIFHDNYHAPTL-ANGSAAELNRIS-------GSVHLGELNQTEAGPVSLPESFILCTRARPLLCLLLMMGTLWVGYTLYQFRRSPFLHVKMREILSDCALPISVLVFSYVGSYVFNDIALPVFNFHEGPV-FQVAPLDKLTGASVLSAMGLGFLLFLLIFIDQNIVVSLTNAPENRLLKGTAYHWDLTLSGLINILMSVLGLPWMHAAFPHSTLHVRQLAIVEERVEGGH-LYETIVSVKETRVTSLVANILIGVSVFLLPVPLQWIPKPVLYGLFLYIALTSIEGNQMCDRMALLLKEQTSYPPTHYIRKVPQRKIHYFTFLQMVQLLFLCAFGMYPLPYMKMIFPLLMFILIPIRNCLLPRIIEAKYLDIMD 778
BLAST of slc4a-8 vs. Ensembl Zebrafish
Match: slc4a11 (solute carrier family 4 member 11 [Source:ZFIN;Acc:ZDB-GENE-090313-183]) HSP 1 Score: 535.798 bits (1379), Expect = 1.466e-176 Identity = 320/795 (40.25%), Postives = 500/795 (62.89%), Query Frame = 2
Query: 509 EDDSVPCLFLSRLEK-IPMKDFSAEVRATLDIQKFLKEAVLLLDMSGSCLEEIIDSMLLTILANEVTDAKVSLEALVEEAKKTLFIQSSYLTYTYQRLAKTIRGLSLSETEGLMTDQSWLCTMCSLNCIHKRHVAIARLNNPVNMGRSSEGIYFIILVVTPTKEKGTKSDIELGRTFATIFADVEFRQQLLFSESVEQFKELL---QYH--------SGDLMEDQAMNRRKSLKVQEVMNQAFHFDKKYLVGSGIVSDFKKRFPVYLMDFRDGFRGKG-TIRKVISATIFLYFACLLPSIAFGVLNYNNTEGKIDVRRVIISQAIGGLCFGFFSGQXXXXXXXXXXXXXFVKIISSICNDYDLDFFAMYSCVGLINSLLLILYAMFDISKLMRWSTRSSEEIFALFVAISFVVDAVKDIYKEFSTHYFSCYLSANNQSTEHLRLSRFKRAFSGIISNIXXXXXXXXXXXXXXXXXXCQREVSILYLFLVAGTVWLAIQLFTSTKTPFLNNAKREMLTDFALPLAVVIMSLIGTYLFKEIEMQPFVIVEEKVKFEASGILKLPWLAIAGAIALAFPLSLLMFMDQNISSAMVNSPANKLKKGSSYHWDLLVVALINAGLSVFGLPLVHGALPHSPLHVKALADLEERIDTAHHVHQTIVKVRETRITSILSHVFIGISLQMLPIPLIYIPVAVLDGLFVYMAVTTLYGNQFFERILLLFTEQSAYPPSHYLRRVPQRKLHIFTGLQIFQLAGLCLLGFSPSPYLKMGFPLLLLFHMVFRHQVVPRVIDEKYLNALD 2854
E D C+ L+ + + + +F EVRA D+ FL+ A +LL + L++++ +ML + + T EE +LF + L++T++ ++ + T G+ QSWLC +C++ + +RHV I+RL+ P N G + + ++IL++ P+K K TK+ +ELGRTFA++F+D+ FRQ+LL S++ E+FKE L +YH + E+ + +K LK ++ + VG GI D +R P+Y DF DG G + K ++ +IFLY A LLP+IAFG LN +T G+IDV++ II Q+IGG+ + +G PL+I LTTAP+A+F+ +I IC+DY+LDF A Y+C+GL NSL LI+ +F++S L++ RS EE+ ALF++I+FV DAVK K F +Y + L AN + E R+S G + ++ T+ S S C R +L L L+ GT+W+ L+ ++PFL+ RE+L+D ALP++V++ S +G+Y+F +I + F E V F+ + + KL ++ A+ L F L LL+F+DQNI ++ N+P N+L KG++YHWDL + LIN +SV GLP +H A PHS LHV+ LA +EER++ H +++TIV V+ETR+TS+++++ IG+S+ +LP+PL +IP VL GLF+Y+A+T++ GNQ +R+ LL EQ++YPP+HY+R+VPQRK+H FT LQ+ QL LC G P PY+KM FPLL+ + R+ ++PR+I+ KYL+ +D
Sbjct: 72 ETDVHGCVLLNTSRRYVKLMNFEEEVRAHRDLDGFLERASILLHEDEASLDDVLKTMLRHVSQDPHTAEP---GCNFEEIMSSLFTDAGSQEVNVHLLSETLQCVTATAT-GIQYQQSWLCILCNVKNLQRRHVCISRLDRPQNWGENCAEVRYVILILAPSKMKSTKTAMELGRTFASMFSDISFRQKLLESKTQEEFKEALVIQRYHLTAAKRKTTAVEGEETDPHSQKPLKCRDF----------FRVGRGIYEDLCRRLPLYPSDFTDGLVGNNKALVKFMTTSIFLYIAVLLPAIAFGSLNDESTRGEIDVQKTIIGQSIGGIIYSLCAGSPLVIPLTTAPIAIFISVIRGICDDYELDFAAFYACIGLWNSLFLIMGGVFNLSLLVKLFKRSIEEVIALFISIAFVADAVKGTVKIFHDNYHAPTL-ANGSAAELNRIS-------GSVHLGELNQTEAGPVSLPESFILCTRARPLLCLLLMMGTLWVGYTLYQFRRSPFLHVKMREILSDCALPISVLVFSYVGSYVFNDIALPVFNFHEGPV-FQVAPLDKLTGASVLSAMGLGFLLFLLIFIDQNIVVSLTNAPENRLLKGTAYHWDLTLSGLINILMSVLGLPWMHAAFPHSTLHVRQLAIVEERVEGGH-LYETIVSVKETRVTSLVANILIGVSVFLLPVPLQWIPKPVLYGLFLYIALTSIEGNQMCDRMALLLKEQTSYPPTHYIRKVPQRKIHYFTFLQMVQLLFLCAFGMYPLPYMKMIFPLLMFILIPIRNCLLPRIIEAKYLDIMD 842
BLAST of slc4a-8 vs. Ensembl Xenopus
Match: SLC4A11 (solute carrier family 4 member 11 [Source:NCBI gene;Acc:100486382]) HSP 1 Score: 593.193 bits (1528), Expect = 0.000e+0 Identity = 337/799 (42.18%), Postives = 500/799 (62.58%), Query Frame = 2
Query: 509 EDDSVPCLFLSRLEK-IPMKDFSAEVRATLDIQKFLKEAVLLLDMSGSCLEEIIDSMLLTILAN-EVTDAKVSLEALVEEAKKTLFIQS-SYLTYTYQRLAKTIRGLSLSETEGLMTDQSWLCTMCSLNCIHKRHVAIARLNNPVNMGRSSEGIYFIILVVTPTKEKGTKSDIELGRTFATIFADVEFRQQLLFSESV----------EQFKELLQYHSGDLMEDQAMNRRKSLKVQEVMNQAFHFDKKYLVGSGIVSDFKKRFPVYLMDFRDGFRGKG-TIRKVISATIFLYFACLLPSIAFGVLNYNNTEGKIDVRRVIISQAIGGLCFGFFSGQXXXXXXXXXXXXXFVKIISSICNDYDLDFFAMYSCVGLINSLLLILYAMFDISKLMRWSTRSSEEIFALFVAISFVVDAVKDIYKEFSTHYF---SCYLSANNQSTEHLRLSRFKRAFSGIISNIXXXXXXXXXXXXXXXXXXCQREVSILYLFLVAGTVWLAIQLFTSTKTPFLNNAKREMLTDFALPLAVVIMSLIGTYLFKEIEMQPFVIVEEKVKFEASGILKLPWLAIAGAIALAFPLSLLMFMDQNISSAMVNSPANKLKKGSSYHWDLLVVALINAGLSVFGLPLVHGALPHSPLHVKALADLEERIDTAHHVHQTIVKVRETRITSILSHVFIGISLQMLPIPLIYIPVAVLDGLFVYMAVTTLYGNQFFERILLLFTEQSAYPPSHYLRRVPQRKLHIFTGLQIFQLAGLCLLGFSPSPYLKMGFPLLLLFHMVFRHQVVPRVIDEKYLNALD 2854
E++S C+ L K + +K+F EVRA D+ FL +A ++LD + + L++++ ML + + E + + ++ TLF S + L+ TI+G++ + T G+ QSWLC +C++ + KRHV I+RL P N G +S + F+ILV+ P K K TK+ E+GRTF+T+F+D+ FRQ+LL +++ L+ HS L + + K LK+ E N VG GI D +R PVY +DF DG G I K I+ IFLYFACLLPSIAFG LN +T G IDV++ I+ Q IGG+ + FSGQPL++LLTTAPLAL++ +I IC+DY+LDF A Y+ GL NS LILY++F+ S LM+ RS+EEI ALF++I+FV+DA+K I K F +Y S + + + +HL F ++++ SS + RE ++L L L+ GT+WL L+ K+P+L++ REML+D ALP++V+ S++G+Y FKEI + F ++ + F + I LP I A+ L F LS+L F++QNI +++ N+P N+L KG++YHWDLL+VALIN GLSVFG+P +H A HS +R + H+++TIV VRETR+TS++++V +G+SL +LP PL +IP VL GLF+Y+A+T++ G+Q FER+ LL EQ+AYPP+HY+RRVPQRK+H FTGLQ+ QL LC G SP PY+KM FPL+++ + R+ ++P++I+ KYL+A+D
Sbjct: 84 ENESSGCVLLHTSRKYLKLKNFEEEVRAHRDLDGFLAKASIILDETATSLDDVLREMLKHFVEDPENAEPSCNFNKIMS----TLFTDSGAPREGNVHLLSDTIQGVTATAT-GVQYQQSWLCIICTIKSLQKRHVCISRLERPQNWGENSCEVRFVILVLAPPKMKSTKTATEVGRTFSTMFSDINFRQKLLETKTEEEFKEALVHQRHLLTLVNKHS-SLNDGHKVQSHKPLKLNEFFN----------VGKGIFDDIARRLPVYPLDFTDGIIGNNKAIGKYITTMIFLYFACLLPSIAFGSLNDESTAGVIDVQKTIVGQCIGGVIYSLFSGQPLVVLLTTAPLALYINVIRGICDDYNLDFKAFYAWTGLWNSCFLILYSLFNCSLLMKLFKRSTEEIIALFISITFVLDALKGIIKIFKKYYLEIPSSHTYPDQEYNKHLPNLNFTSDV--LLNSTFNGSVFAPNGSSDHEEIHYGRESAVLSLMLMFGTLWLGHTLYQFKKSPYLHSRVREMLSDCALPISVLTFSVVGSYFFKEIHIAKFNYIKTESMFVLAPIGSLPMGPITSAMGLGFLLSMLFFIEQNIVASLTNAPENRLVKGTAYHWDLLLVALINTGLSVFGMPWIHAAFLHSHNARAGARQSWKREWSTGHIYETIVSVRETRLTSLVANVLVGLSLFLLPYPLQWIPKPVLYGLFLYIALTSIDGSQLFERVALLLKEQTAYPPTHYIRRVPQRKIHYFTGLQVLQLVILCGFGMSPLPYMKMIFPLIMIGMIPIRYNLLPKIIESKYLDAMD 864
BLAST of slc4a-8 vs. Ensembl Xenopus
Match: SLC4A11 (solute carrier family 4 member 11 [Source:NCBI gene;Acc:100486382]) HSP 1 Score: 592.808 bits (1527), Expect = 0.000e+0 Identity = 337/799 (42.18%), Postives = 500/799 (62.58%), Query Frame = 2
Query: 509 EDDSVPCLFLSRLEK-IPMKDFSAEVRATLDIQKFLKEAVLLLDMSGSCLEEIIDSMLLTILAN-EVTDAKVSLEALVEEAKKTLFIQS-SYLTYTYQRLAKTIRGLSLSETEGLMTDQSWLCTMCSLNCIHKRHVAIARLNNPVNMGRSSEGIYFIILVVTPTKEKGTKSDIELGRTFATIFADVEFRQQLLFSESV----------EQFKELLQYHSGDLMEDQAMNRRKSLKVQEVMNQAFHFDKKYLVGSGIVSDFKKRFPVYLMDFRDGFRGKG-TIRKVISATIFLYFACLLPSIAFGVLNYNNTEGKIDVRRVIISQAIGGLCFGFFSGQXXXXXXXXXXXXXFVKIISSICNDYDLDFFAMYSCVGLINSLLLILYAMFDISKLMRWSTRSSEEIFALFVAISFVVDAVKDIYKEFSTHYF---SCYLSANNQSTEHLRLSRFKRAFSGIISNIXXXXXXXXXXXXXXXXXXCQREVSILYLFLVAGTVWLAIQLFTSTKTPFLNNAKREMLTDFALPLAVVIMSLIGTYLFKEIEMQPFVIVEEKVKFEASGILKLPWLAIAGAIALAFPLSLLMFMDQNISSAMVNSPANKLKKGSSYHWDLLVVALINAGLSVFGLPLVHGALPHSPLHVKALADLEERIDTAHHVHQTIVKVRETRITSILSHVFIGISLQMLPIPLIYIPVAVLDGLFVYMAVTTLYGNQFFERILLLFTEQSAYPPSHYLRRVPQRKLHIFTGLQIFQLAGLCLLGFSPSPYLKMGFPLLLLFHMVFRHQVVPRVIDEKYLNALD 2854
E++S C+ L K + +K+F EVRA D+ FL +A ++LD + + L++++ ML + + E + + ++ TLF S + L+ TI+G++ + T G+ QSWLC +C++ + KRHV I+RL P N G +S + F+ILV+ P K K TK+ E+GRTF+T+F+D+ FRQ+LL +++ L+ HS L + + K LK+ E N VG GI D +R PVY +DF DG G I K I+ IFLYFACLLPSIAFG LN +T G IDV++ I+ Q IGG+ + FSGQPL++LLTTAPLAL++ +I IC+DY+LDF A Y+ GL NS LILY++F+ S LM+ RS+EEI ALF++I+FV+DA+K I K F +Y S + + + +HL F ++++ SS + RE ++L L L+ GT+WL L+ K+P+L++ REML+D ALP++V+ S++G+Y FKEI + F ++ + F + I LP I A+ L F LS+L F++QNI +++ N+P N+L KG++YHWDLL+VALIN GLSVFG+P +H A HS +R + H+++TIV VRETR+TS++++V +G+SL +LP PL +IP VL GLF+Y+A+T++ G+Q FER+ LL EQ+AYPP+HY+RRVPQRK+H FTGLQ+ QL LC G SP PY+KM FPL+++ + R+ ++P++I+ KYL+A+D
Sbjct: 81 ENESSGCVLLHTSRKYLKLKNFEEEVRAHRDLDGFLAKASIILDETATSLDDVLREMLKHFVEDPENAEPSCNFNKIMS----TLFTDSGAPREGNVHLLSDTIQGVTATAT-GVQYQQSWLCIICTIKSLQKRHVCISRLERPQNWGENSCEVRFVILVLAPPKMKSTKTATEVGRTFSTMFSDINFRQKLLETKTEEEFKEALVHQRHLLTLVNKHS-SLNDGHKVQSHKPLKLNEFFN----------VGKGIFDDIARRLPVYPLDFTDGIIGNNKAIGKYITTMIFLYFACLLPSIAFGSLNDESTAGVIDVQKTIVGQCIGGVIYSLFSGQPLVVLLTTAPLALYINVIRGICDDYNLDFKAFYAWTGLWNSCFLILYSLFNCSLLMKLFKRSTEEIIALFISITFVLDALKGIIKIFKKYYLEIPSSHTYPDQEYNKHLPNLNFTSDV--LLNSTFNGSVFAPNGSSDHEEIHYGRESAVLSLMLMFGTLWLGHTLYQFKKSPYLHSRVREMLSDCALPISVLTFSVVGSYFFKEIHIAKFNYIKTESMFVLAPIGSLPMGPITSAMGLGFLLSMLFFIEQNIVASLTNAPENRLVKGTAYHWDLLLVALINTGLSVFGMPWIHAAFLHSHNARAGARQSWKREWSTGHIYETIVSVRETRLTSLVANVLVGLSLFLLPYPLQWIPKPVLYGLFLYIALTSIDGSQLFERVALLLKEQTAYPPTHYIRRVPQRKIHYFTGLQVLQLVILCGFGMSPLPYMKMIFPLIMIGMIPIRYNLLPKIIESKYLDAMD 861
BLAST of slc4a-8 vs. Ensembl Xenopus
Match: SLC4A11 (solute carrier family 4 member 11 [Source:NCBI gene;Acc:100486382]) HSP 1 Score: 567.385 bits (1461), Expect = 0.000e+0 Identity = 325/772 (42.10%), Postives = 485/772 (62.82%), Query Frame = 2
Query: 539 SRLEKIPMKDFSAEVRATLDIQKFLKEAVLLLDMSGSCLEEIIDSMLLTILANEVTDAKVSLEALVEEAKKTLFIQS-SYLTYTYQRLAKTIRGLSLSETEGLMTDQSWLCTMCSLNCIHKRHVAIARLNNPVNMGRSSEGIYFIILVVTPTKEKGTKSDIELGRTFATIFADVEFRQQLLFSESV----------EQFKELLQYHSGDLMEDQAMNRRKSLKVQEVMNQAFHFDKKYLVGSGIVSDFKKRFPVYLMDFRDGFRGKG-TIRKVISATIFLYFACLLPSIAFGVLNYNNTEGKIDVRRVIISQAIGGLCFGFFSGQXXXXXXXXXXXXXFVKIISSICNDYDLDFFAMYSCVGLINSLLLILYAMFDISKLMRWSTRSSEEIFALFVAISFVVDAVKDIYKEFSTHYF---SCYLSANNQSTEHLRLSRFKRAFSGIISNIXXXXXXXXXXXXXXXXXXCQREVSILYLFLVAGTVWLAIQLFTSTKTPFLNNAKREMLTDFALPLAVVIMSLIGTYLFKEIEMQPFVIVEEKVKFEASGILKLPWLAIAGAIALAFPLSLLMFMDQNISSAMVNSPANKLKKGSSYHWDLLVVALINAGLSVFGLPLVHGALPHSPLHVKALADLEERIDTAHHVHQTIVKVRETRITSILSHVFIGISLQMLPIPLIYIPVAVLDGLFVYMAVTTLYGNQFFERILLLFTEQSAYPPSHYLRRVPQRKLHIFTGLQIFQLAGLCLLGFSPSPYLKMGFPLLLLFHMVFRHQ 2809
+++ + +K+F EVRA D+ FL +A ++LD + + L++++ ML + + +A+ S + TLF S + L+ TI+G++ + T G+ QSWLC +C++ + KRHV I+RL P N G +S + F+ILV+ P K K TK+ E+GRTF+T+F+D+ FRQ+LL +++ L+ HS L + + K LKV+ + ++ + VG GI D +R PVY +DF DG G I K I+ IFLYFACLLPSIAFG LN +T G IDV++ I+ Q IGG+ + FSGQPL++LLTTAPLAL++ +I IC+DY+LDF A Y+ GL NS LILY++F+ S LM+ RS+EEI ALF++I+FV+DA+K I K F +Y S + + + +HL F ++++ SS + RE ++L L L+ GT+WL L+ K+P+L++ REML+D ALP++V+ S++G+Y FKEI + F ++ + F + I LP I A+ L F LS+L F++QNI +++ N+P N+L KG++YHWDLL+VALIN GLSVFG+P +H A HS +R + H+++TIV VRETR+TS++++V +G+SL +LP PL +IP VL GLF+Y+A+T++ G+Q FER+ LL EQ+AYPP+HY+RRVPQRK+H FTGLQ+ QL LC G SP PY+KM FPL+++ + R++
Sbjct: 86 TQITYLKLKNFEEEVRAHRDLDGFLAKASIILDETATSLDDVLREMLKHFVEDP-ENAEPSCN--FNKIMSTLFTDSGAPREGNVHLLSDTIQGVTATAT-GVQYQQSWLCIICTIKSLQKRHVCISRLERPQNWGENSCEVRFVILVLAPPKMKSTKTATEVGRTFSTMFSDINFRQKLLETKTEEEFKEALVHQRHLLTLVNKHS-SLNDGHKVQSHKPLKVRG--SSPPKLNEFFNVGKGIFDDIARRLPVYPLDFTDGIIGNNKAIGKYITTMIFLYFACLLPSIAFGSLNDESTAGVIDVQKTIVGQCIGGVIYSLFSGQPLVVLLTTAPLALYINVIRGICDDYNLDFKAFYAWTGLWNSCFLILYSLFNCSLLMKLFKRSTEEIIALFISITFVLDALKGIIKIFKKYYLEIPSSHTYPDQEYNKHLPNLNFTSDV--LLNSTFNGSVFAPNGSSDHEEIHYGRESAVLSLMLMFGTLWLGHTLYQFKKSPYLHSRVREMLSDCALPISVLTFSVVGSYFFKEIHIAKFNYIKTESMFVLAPIGSLPMGPITSAMGLGFLLSMLFFIEQNIVASLTNAPENRLVKGTAYHWDLLLVALINTGLSVFGMPWIHAAFLHSHNARAGARQSWKREWSTGHIYETIVSVRETRLTSLVANVLVGLSLFLLPYPLQWIPKPVLYGLFLYIALTSIDGSQLFERVALLLKEQTAYPPTHYIRRVPQRKIHYFTGLQVLQLVILCGFGMSPLPYMKMIFPLIMIGMIPIRYR 848
BLAST of slc4a-8 vs. Ensembl Xenopus
Match: SLC4A11 (solute carrier family 4 member 11 [Source:NCBI gene;Acc:100486382]) HSP 1 Score: 553.903 bits (1426), Expect = 0.000e+0 Identity = 324/762 (42.52%), Postives = 469/762 (61.55%), Query Frame = 2
Query: 560 MKDFSAEVRATLDIQKFLKEAVLLLDMSGSCLEEIIDSMLLTILANEVTDAKVSLEALVEEAKKTLFIQS-SYLTYTYQRLAKTIRGLSLSETEGLMTDQSWLCTMCSLNCIHKRHVAIARLNNPVNMGRSSEGIYFIILVVTPTKEKGTKSDIELGRTFATIFADVEFRQQLLFSESV----------EQFKELLQYHSGDLMEDQAMNRRKSLKVQEVMNQAFHFDKKYLVGSGIVSDFKKRFPVYLMDFRDGFRGKG-TIRKVISATIFLYFACLLPSIAFGVLNYNNTEGKIDVRRVIISQAIGGLCFGFFSGQXXXXXXXXXXXXXFVKIISSICNDYDLDFFAMYSCVGLINSLLLILYAMFDISKLMRWSTRSSEEIFALFVAISFVVDAVKDIYKEFSTHYFSCYLSANNQSTEHLRLSRFKRAFSGIISNIXXXXXXXXXXXXXXXXXXCQREVSILYLFLVAGTVWLAIQLFTSTKTPFLNNAKREMLTDFALPLAVVIMSLIGTYLFKEIEMQPFVIVEEKVKFEASGILKLPWLAIAGAIALAFPLSLLMFMDQNISSAMVNSPANKLKKGSSYHWDLLVVALINAGLSVFGLPLVHGALPHSPLHVKALADLEERIDTAHHVHQTIVKVRETRITSILSHVFIGISLQMLPIPLIYIPVAVLDGLFVYMAVTTLYGNQFFERILLLFTEQSAYPPSHYLRRVPQRKLHIFTGLQIFQLAGLCLLGFSPSPYLKMGFPLLLLFHMVFRHQ 2809
+K+F EVRA D+ FL +A ++LD + + L++++ ML + + +A+ S + TLF S + L+ TI+G++ + T G+ QSWLC +C++ + KRHV I+RL P N G +S + F+ILV+ P K K TK+ E+GRTF+T+F+D+ FRQ+LL +++ L+ HS L + + K LK+ E N VG GI D +R PVY +DF DG G I K I+ IFLYFACLLPSIAFG LN +T G IDV++ I+ Q IGG+ + FSGQPL++LLTTAPLAL++ +I IC+DY+LDF A Y+ GL NS LILY++F+ S LM+ RS+EEI ALF++I+FV+DA+K I K S +Y Q+ ++RL +K Y+ RE ++L L L+ GT+WL L+ K+P+L++ REML+D ALP++V+ S++G+Y FKEI + F + I LP I A+ L F LS+L F++QNI +++ N+P N+L KG++YHWDLL+VALIN GLSVFG+P +H A HS +R + H+++TIV VRETR+TS++++V +G+SL +LP PL +IP VL GLF+Y+A+T++ G+Q FER+ LL EQ+AYPP+HY+RRVPQRK+H FTGLQ+ QL LC G SP PY+KM FPL+++ + R++
Sbjct: 21 LKNFEEEVRAHRDLDGFLAKASIILDETATSLDDVLREMLKHFVEDP-ENAEPSCN--FNKIMSTLFTDSGAPREGNVHLLSDTIQGVTATAT-GVQYQQSWLCIICTIKSLQKRHVCISRLERPQNWGENSCEVRFVILVLAPPKMKSTKTATEVGRTFSTMFSDINFRQKLLETKTEEEFKEALVHQRHLLTLVNKHS-SLNDGHKVQSHKPLKLNEFFN----------VGKGIFDDIARRLPVYPLDFTDGIIGNNKAIGKYITTMIFLYFACLLPSIAFGSLNDESTAGVIDVQKTIVGQCIGGVIYSLFSGQPLVVLLTTAPLALYINVIRGICDDYNLDFKAFYAWTGLWNSCFLILYSLFNCSLLMKLFKRSTEEIIALFISITFVLDALKGIIKSKSIYY--------PQTNSNMRLV-WKELLG-------------------YTEIHYGRESAVLSLMLMFGTLWLGHTLYQFKKSPYLHSRVREMLSDCALPISVLTFSVVGSYFFKEIHSK------LPDMFVLAPIGSLPMGPITSAMGLGFLLSMLFFIEQNIVASLTNAPENRLVKGTAYHWDLLLVALINTGLSVFGMPWIHAAFLHSHNARAGARQSWKREWSTGHIYETIVSVRETRLTSLVANVLVGLSLFLLPYPLQWIPKPVLYGLFLYIALTSIDGSQLFERVALLLKEQTAYPPTHYIRRVPQRKIHYFTGLQVLQLVILCGFGMSPLPYMKMIFPLIMIGMIPIRYR 733
BLAST of slc4a-8 vs. Ensembl Xenopus
Match: SLC4A11 (solute carrier family 4 member 11 [Source:NCBI gene;Acc:100486382]) HSP 1 Score: 533.872 bits (1374), Expect = 1.762e-176 Identity = 324/770 (42.08%), Postives = 473/770 (61.43%), Query Frame = 2
Query: 509 EDDSVPCLFLSRLEK-IPMKDFSAEVRATLDIQKFLKEAVLLLDMSGSCLEEIIDSMLLTILANEVTDAKVSLEALVEEAKKTLFIQS-SYLTYTYQRLAKTIRGLSLSETEGLMTDQSWLCTMCSLNCIHKRHVAIARLNNPVNMGRSSEGIYFIILVVTPTKEKGTKSDIELGRTFATIFADVEFRQQLLFSESVEQFKELLQYHSGDLMEDQAMNRRKSLKVQEVMNQAFHFDKKYLVGSGIVSDFKKRFPVYLMDFRDGFRGKG-TIRKVISATIFLYFACLLPSIAFGVLNYNNTEGKIDVRRVIISQAIGGLCFGFFSGQXXXXXXXXXXXXXFVKIISSICNDYDLDFFAMYSCVGLINSLLLILYAMFDISKLMRWSTRSSEEIFALFVAISFVVDAVKDIYKEFSTHYFSCYLSANNQSTEHLRLSRFKRAFSGIISNIXXXXXXXXXXXXXXXXXXCQREVSILYLFLVAGTVWLAIQLFTSTKTPFLNNAKREMLTDFALPLAVVIMSLIGTYLFKEIEMQPFVIVEEKVKFEASGILKLPWLAIAGAIALAFPLSLLMFMDQNISSAMVNSPANKLKKGSSYHWDLLVVALINAGLSVFGLPLVHGALPHSPLHVKALADLEERIDTAHHVHQTIVKVRETRITSILSHVFIGISLQMLPIPLIYIPVAVLDGLFVYMAVTTLYGNQFFERILLLFTEQSAYPPSHYLRRVPQRKLHIFTGLQIFQLAGLCLLGFSPSPYLKMGFPLLLLFHMVFRHQ 2809
E++S C+ L K + +K+F EVRA D+ FL +A ++LD + + L++++ ML + + +A+ S + TLF S + L+ TI+G++ + T G+ QSWLC +C++ + KRHV I+RL P N G +S + F+ILV+ P K K TK+ E+GRTF+T+F+D+ FRQ+LL +++ E+FKE L H L+ +N+ SL +N+ F+ VG GI D +R PVY +DF DG G I K I+ IFLYFACLLPSIAFG LN +T G IDV++ I+ Q IGG+ + FSGQPL++LLTTAPLAL++ +I IC+DY+LDF A Y+ GL NS LILY++F+ S LM+ RS+EEI ALF++I+FV+DA+K I K S + C +S + + +GI+ R+ + Y G +WL P+L++ REML+D ALP++V+ S++G+Y FKEI + F + I LP I A+ L F LS+L F++QNI +++ N+P N+L KG++YHWDLL+VALIN GLSVFG+P +H A HS +R + H+++TIV VRETR+TS++++V +G+SL +LP PL +IP VL GLF+Y+A+T++ G+Q FER+ LL EQ+AYPP+HY+RRVPQRK+H FTGLQ+ QL LC G SP PY+KM FPL+++ + R++
Sbjct: 66 ENESSGCVLLHTSRKYLKLKNFEEEVRAHRDLDGFLAKASIILDETATSLDDVLREMLKHFVEDP-ENAEPSCN--FNKIMSTLFTDSGAPREGNVHLLSDTIQGVTATAT-GVQYQQSWLCIICTIKSLQKRHVCISRLERPQNWGENSCEVRFVILVLAPPKMKSTKTATEVGRTFSTMFSDINFRQKLLETKTEEEFKEAL-VHQRHLL--TLVNKHSSLNDGHKLNEFFN------VGKGIFDDIARRLPVYPLDFTDGIIGNNKAIGKYITTMIFLYFACLLPSIAFGSLNDESTAGVIDVQKTIVGQCIGGVIYSLFSGQPLVVLLTTAPLALYINVIRGICDDYNLDFKAFYAWTGLWNSCFLILYSLFNCSLLMKLFKRSTEEIIALFISITFVLDALKGIIKSKSIY---CIISVRPLGRD------WGCGIAGIVG----------------------RDGA--YSSSGWGGLWL----------PYLHSRVREMLSDCALPISVLTFSVVGSYFFKEIHSK------LPDMFVLAPIGSLPMGPITSAMGLGFLLSMLFFIEQNIVASLTNAPENRLVKGTAYHWDLLLVALINTGLSVFGMPWIHAAFLHSHNARAGARQSWKREWSTGHIYETIVSVRETRLTSLVANVLVGLSLFLLPYPLQWIPKPVLYGLFLYIALTSIDGSQLFERVALLLKEQTAYPPTHYIRRVPQRKIHYFTGLQVLQLVILCGFGMSPLPYMKMIFPLIMIGMIPIRYR 773
BLAST of slc4a-8 vs. Ensembl Mouse
Match: Slc4a11 (solute carrier family 4, sodium bicarbonate transporter-like, member 11 [Source:MGI Symbol;Acc:MGI:2138987]) HSP 1 Score: 563.148 bits (1450), Expect = 0.000e+0 Identity = 350/822 (42.58%), Postives = 516/822 (62.77%), Query Frame = 2
Query: 449 NMSNISGSTLAYCLQ-------NADETEDDSVPCLFLSRLEK-IPMKDFSAEVRATLDIQKFLKEAVLLLDMSGSCLEEIIDSMLLTIL-----ANEVTDAKVSLEALVEEAKKTLFIQSSYLTYTYQRLAKTIRGLSLSETEGLMTDQSWLCTMCSLNCIHKRHVAIARLNNPVNMGRSSEGIYFIILVVTPTKEKGTKSDIELGRTFATIFADVEFRQQLLFSESVEQFKELLQYHSGDL---MEDQAMNRRKSLKVQEVMNQAFHFDKKYLVGSGIVSDFKKRFPVYLMDFRDGFRGKG-TIRKVISATIFLYFACLLPSIAFGVLNYNNTEGKIDVRRVIISQAIGGLCFGFFSGQXXXXXXXXXXXXXFVKIISSICNDYDLDFFAMYSCVGLINSLLLILYAMFDISKLMRWSTRSSEEIFALFVAISFVVDAVKDIYKEFSTHYFSCYLSANNQSTEHLRLSRFKRAFSGIISNIXXXXXXXXXXXXXXXX---XXCQREVSILYLFLVAGTVWLAIQLFTSTKTPFLNNAKREMLTDFALPLAVVIMSLIGTYLFKEIEMQPFVIVEEKVKFEASGILKLPWLAIAGAIALAFPLSLLMFMDQNISSAMVNSPANKLKKGSSYHWDLLVVALINAGLSVFGLPLVHGALPHSPLHVKALADLEERIDTAHHVHQTIVKVRETRITSILSHVFIGISLQMLPIPLIYIPVAVLDGLFVYMAVTTLYGNQFFERILLLFTEQSAYPPSHYLRRVPQRKLHIFTGLQIFQLAGLCLLGFSPSPYLKMGFPLLLLFHMVFRHQVVPRVIDEKYLNALD 2854
N S +SG ++ + + + + E + C+ L K + +K+F EVRA D+ FL +A ++L+ + + L++++ +ML A D + + L +A + + L+ T Q + T+RG+ +QSWLC +C++ + KRHV I+RL P N G +S + F+ILV+ P K K TK+ +E+ RTFAT+F+D+ FRQ+LL + + E+FKE L + L M A + SL Q + G GI D +RFPVY MDF DG GK ++ K ++ T+FLYFACLLP+IAFG LN NT G IDV++ I Q+IGGL + FSGQPL+ILLTTAPLA++ ++I IC+DY+LDF A Y+ GL NS L LYA ++S LM RS+EEI ALF++I+FV+DAVK + K F +Y+ + S+ L + S + + ++ SL + + + SS + ++L L ++ GT+WL L+ K+P+L+ RE L+D ALP+AV+ SLIG+Y F+EIEM F + FE + I L + AI A+ L F LSLL F++QN+ +A+VN+P N+L KG++YHWDLL++A+IN GLS+FGLP +H A PHSPLHV+ALA +EER++ H+++TIV V+ETR+T++ + V +G+SL +LP PL +IP VL GLF+Y+A+T+L GNQ F R+ LL EQ++YPP+HY+RRVPQRK+H FTGLQI QL LC G S PY+KM FPL+++ + R+ ++PR+I+ KYL+ +D
Sbjct: 46 NSSIVSGESIRFFVNVNLEVQPSKSDLEAATGGCVLLHTSRKYLKLKNFEEEVRAHRDLDGFLAQASIILNETATSLDDVLRTMLNRFALDPNHAEPDCDLDLLMAKLFTDAGAPMESKVHLLSDTIQGVTATVRGVQY--------EQSWLCIICTMKTLQKRHVCISRLVRPQNWGENSCEVRFVILVLAPPKMKSTKTAMEVARTFATMFSDITFRQKLLKTRTEEEFKEALVHQRQLLTMMMPRAAGHSMSSLHTHR-HPQPPKCKDFFPFGKGIWMDIMRRFPVYPMDFTDGIIGKSKSVGKYVTTTLFLYFACLLPTIAFGSLNDENTNGAIDVQKTIAGQSIGGLLYALFSGQPLVILLTTAPLAIYTQVIRVICDDYNLDFNAFYAWTGLWNSFFLALYAFLNLSLLMNLFKRSTEEIIALFISITFVLDAVKGMVKIFGKYYYGHHYHTKRTSSLVSLLGIGRSPNSSLHTALNASLLASPVEMATTSSPGSTHSGQATAVLSLLIMLGTLWLGYTLYQFKKSPYLHPCVRETLSDCALPIAVLSFSLIGSYGFQEIEMSKFRYNPSESLFEVAQIHSLSFKAIGSAMGLGFLLSLLFFIEQNLVAALVNAPENRLVKGTAYHWDLLLLAIINTGLSLFGLPWIHAAYPHSPLHVRALALVEERVENG-HIYETIVDVKETRLTALGASVLVGLSLLLLPFPLQWIPKPVLYGLFLYIALTSLDGNQLFSRVALLLKEQTSYPPTHYIRRVPQRKIHYFTGLQILQLLLLCAFGMSSLPYMKMVFPLIMIAMIPIRYNLLPRIIEAKYLDVMD 857
BLAST of slc4a-8 vs. Ensembl Mouse
Match: Slc4a1 (solute carrier family 4 (anion exchanger), member 1 [Source:MGI Symbol;Acc:MGI:109393]) HSP 1 Score: 202.601 bits (514), Expect = 3.254e-53 Identity = 159/559 (28.44%), Postives = 277/559 (49.55%), Query Frame = 2
Query: 1229 SGIVSDFKKRFPVYLMDFRDGFRGKGTIRKVISATIFLYFACLLPSIAFGVLNYNNTEGKIDVRRVIISQAIGGLCFGFFSGQXXXXXXXXXXXXXFVKIISSICNDYDLDFFAMYSCVGLINSLLLILYAMFDISKLMRWSTRSSEEIFALFVAISFVVDAVKDIYKEFSTHYFSCYLSANNQSTEHLRLSRFKRAFSGIISNIXXXXXXXXXXXXXXXXXXCQREVSILYLFLVAGTVWLAIQLFTSTKTPFLNNAKREMLTDFALPLAVVIMSLI-----GTYLFKEIEMQPFVIVEEKVKFEAS----------GILKL--PWLAIAGAIALAFPLSLLMFMDQNISSAMVNSPANKLKKGSSYHWDLLVVALINAGLSVFGLPLVHGALPHSPLHVKALADLEERIDTAHHVHQTIVKVRETRITSILSHVFIGISLQMLPIPLIYIPVAVLDGLFVYMAVTTLYGNQFFERILLLFTEQSAYPPSHYLRRVPQRKLHIFTGLQIFQLAGLCLLGFSPSPYLKMGFPLLLLFHMVFRHQVVPRVIDEKYLNALD 2854
G++ D ++R+P YL D D +V++A IF+YFA L P++ FG L T + V ++IS A+ G+ F QPL++L + PL +F + S C +L++ + +G LL++L F+ S L+++ +R ++EIF+ +++ F+ + + K F + Q T + + K G + N ++ L L+AGT LA+ L + + R ++ DF +P++++IM L+ GTY K + V + +K S G+ +L W+ A + A + +L+F++ I++ +V+ P K+ KGS +H DLL+V + ++FG+P + S H AL + + + I +V+E RI+ +L V +G+S+ M PI L IP+AVL G+F+YM VT+L G Q F+RILLLF +P +++RV ++H+FTG+QI LA L ++ +P+ + P +L+ + R ++P + E L LD
Sbjct: 399 GGLIRDIRRRYPYYLSDITDALS-----PQVLAAVIFIYFAALSPAVTFGGLLGEKTRNLMGVSELLISTAVQGILFALLGAQPLLVLGFSGPLLVFEEAFFSFCESNNLEYIVGRAWIGFWLILLVMLVVAFEGSFLVQYISRYTQEIFSFLISLIFIYETFSKLIKIFQDYPL--------QQTYAPVVMKPKP--QGPVPN-----------------------TALFSLVLMAGTFLLAMTLRKFKNSTYFPGKLRRVIGDFGVPISILIMVLVDSFIKGTYTQK-------LSVPDGLKVSNSSARGWVIHPLGLYRLFPTWMMFASVLP-ALLVFILIFLESQITTLIVSKPERKMIKGSGFHLDLLLVVGMGGVAALFGMPWLSATTVRSVTHANALTVMGKA--SGPGAAAQIQEVKEQRISGLLVSVLVGLSILMEPI-LSRIPLAVLFGIFLYMGVTSLSGIQLFDRILLLFKPPKYHPDVPFVKRVKTWRMHLFTGIQIICLAVLWVVKSTPA---SLALPFVLILTVPLRRLILPLIFRELELQCLD 905
BLAST of slc4a-8 vs. Ensembl Mouse
Match: Slc4a8 (solute carrier family 4 (anion exchanger), member 8 [Source:MGI Symbol;Acc:MGI:1928745]) HSP 1 Score: 199.904 bits (507), Expect = 3.693e-52 Identity = 167/568 (29.40%), Postives = 283/568 (49.82%), Query Frame = 2
Query: 1229 SGIVSDFKKRFPVYLMDFRDGFRGKGTIRKVISATIFLYFACLLPSIAFGVLNYNNTEGKIDVRRVIISQAIGGLCFGFFSGQXXXXXXXXXXXXXFVKIISSICNDYDLDFFAMYSCVGLINSLLLILYAMFDISKLMRWSTRSSEEIFALFVAISFVVDAVKDI--------------YKEFSTHYFSCYLSANNQSTEHLRLSRFKRAFSGIISNIXXXXXXXXXXXXXXXXXXCQRE----VSILY----LFLVAGTVWLAIQLFTSTKTPFLNNAKREMLTDFALPLAVVIMS----LIGTYLFKEIEMQPFVIVEEKVKFEASGILKLPWLAIAGAIALAFPLSLLMFMDQNISSAMVNSPANKLKKGSSYHWDLLVVALINAGLSVFGLPLVHGALPHSPLHVKALADLEERIDTAHHVHQTIVKVRETRITSILSHVFIGISLQMLPIPLIYIPVAVLDGLFVYMAVTTLYGNQFFERILLLFTEQSAYPPSHYLRRVPQRKLHIFTGLQIFQLAGLCLLGFSPSPYLKMGFPLLLLFHMVFRHQVVPRVIDEKYLNALD 2854
G+V D K++ P Y D+RD + +++ +FLY AC+ P I FG L TEG+I + ++ G+ + F+GQPL IL +T P+ +F KI+ C DY L + ++ + +GL + L I+ D S L+ + TR +EE FA + I F+ +A++ + S +Y C L N + L+ + + ++ ++++++ + ++C +L+ LF V ++ F +++ + R M++DFA+ L + M LIG K F + + + I PW + AI A ++L+FMDQ I++ ++N +KLKKG YH DLL+VA++ S+ GLP A S HV +L LE +A + +RE R+T ++ V +G S+ M + L +IP+ VL G+F+YM V++L G QFF+R+ L P YLR VP RK+H+FT +Q+ L L ++ SP+ + FP+++L +VF +V+ ++ L+ LD
Sbjct: 399 GGLVLDVKRKAPWYWSDYRDALS-----LQCLASFLFLYCACMSPVITFGGLLGEATEGRISAIESLFGASMTGIAYSLFAGQPLTILGSTGPVLVFEKILFKFCKDYALSYLSLRALIGLWTAFLCIVLVATDASSLVCYITRFTEEAFASLICIIFIYEAIEKLIHLAETYPIHMHSQLDHLSLYYCRCVL-PENPNNHTLQYWKDHNILAAEVNWANLTVSECQEMHGEFMGSACGHHGPYTPDVLFWSCILFFATFIVSSTLKTFKTSR--YFPTRVRSMVSDFAVFLTIFTMVVLDFLIGVPSPKLQVPNVFKPTRDDRGWFINPIGPNPWWTVIAAIIPALLCTILIFMDQQITAVIINRKEHKLKKGCGYHLDLLMVAVMLGVCSIMGLPWFVAATVLSITHVNSLK-LESEC-SAPGEQPKFLGIREQRVTGLMIFVLMGCSVFMTAV-LKFIPMPVLYGVFLYMGVSSLQGIQFFDRLKLFGMPAKHQPDFIYLRHVPLRKVHLFTLVQLTCLVLLWVIKASPAAIV---FPMMVL-ALVFVRKVMDLCFSKRELSWLD 951
BLAST of slc4a-8 vs. Ensembl Mouse
Match: Slc4a8 (solute carrier family 4 (anion exchanger), member 8 [Source:MGI Symbol;Acc:MGI:1928745]) HSP 1 Score: 199.519 bits (506), Expect = 6.663e-52 Identity = 167/568 (29.40%), Postives = 283/568 (49.82%), Query Frame = 2
Query: 1229 SGIVSDFKKRFPVYLMDFRDGFRGKGTIRKVISATIFLYFACLLPSIAFGVLNYNNTEGKIDVRRVIISQAIGGLCFGFFSGQXXXXXXXXXXXXXFVKIISSICNDYDLDFFAMYSCVGLINSLLLILYAMFDISKLMRWSTRSSEEIFALFVAISFVVDAVKDI--------------YKEFSTHYFSCYLSANNQSTEHLRLSRFKRAFSGIISNIXXXXXXXXXXXXXXXXXXCQRE----VSILY----LFLVAGTVWLAIQLFTSTKTPFLNNAKREMLTDFALPLAVVIMS----LIGTYLFKEIEMQPFVIVEEKVKFEASGILKLPWLAIAGAIALAFPLSLLMFMDQNISSAMVNSPANKLKKGSSYHWDLLVVALINAGLSVFGLPLVHGALPHSPLHVKALADLEERIDTAHHVHQTIVKVRETRITSILSHVFIGISLQMLPIPLIYIPVAVLDGLFVYMAVTTLYGNQFFERILLLFTEQSAYPPSHYLRRVPQRKLHIFTGLQIFQLAGLCLLGFSPSPYLKMGFPLLLLFHMVFRHQVVPRVIDEKYLNALD 2854
G+V D K++ P Y D+RD + +++ +FLY AC+ P I FG L TEG+I + ++ G+ + F+GQPL IL +T P+ +F KI+ C DY L + ++ + +GL + L I+ D S L+ + TR +EE FA + I F+ +A++ + S +Y C L N + L+ + + ++ ++++++ + ++C +L+ LF V ++ F +++ + R M++DFA+ L + M LIG K F + + + I PW + AI A ++L+FMDQ I++ ++N +KLKKG YH DLL+VA++ S+ GLP A S HV +L LE +A + +RE R+T ++ V +G S+ M + L +IP+ VL G+F+YM V++L G QFF+R+ L P YLR VP RK+H+FT +Q+ L L ++ SP+ + FP+++L +VF +V+ ++ L+ LD
Sbjct: 451 GGLVLDVKRKAPWYWSDYRDALS-----LQCLASFLFLYCACMSPVITFGGLLGEATEGRISAIESLFGASMTGIAYSLFAGQPLTILGSTGPVLVFEKILFKFCKDYALSYLSLRALIGLWTAFLCIVLVATDASSLVCYITRFTEEAFASLICIIFIYEAIEKLIHLAETYPIHMHSQLDHLSLYYCRCVL-PENPNNHTLQYWKDHNILAAEVNWANLTVSECQEMHGEFMGSACGHHGPYTPDVLFWSCILFFATFIVSSTLKTFKTSR--YFPTRVRSMVSDFAVFLTIFTMVVLDFLIGVPSPKLQVPNVFKPTRDDRGWFINPIGPNPWWTVIAAIIPALLCTILIFMDQQITAVIINRKEHKLKKGCGYHLDLLMVAVMLGVCSIMGLPWFVAATVLSITHVNSLK-LESEC-SAPGEQPKFLGIREQRVTGLMIFVLMGCSVFMTAV-LKFIPMPVLYGVFLYMGVSSLQGIQFFDRLKLFGMPAKHQPDFIYLRHVPLRKVHLFTLVQLTCLVLLWVIKASPAAIV---FPMMVL-ALVFVRKVMDLCFSKRELSWLD 1003
BLAST of slc4a-8 vs. Ensembl Mouse
Match: Slc4a10 (solute carrier family 4, sodium bicarbonate cotransporter-like, member 10 [Source:MGI Symbol;Acc:MGI:2150150]) HSP 1 Score: 194.126 bits (492), Expect = 3.214e-50 Identity = 164/565 (29.03%), Postives = 285/565 (50.44%), Query Frame = 2
Query: 1229 SGIVSDFKKRFPVYLMDFRDGFRGKGTIRKVISATIFLYFACLLPSIAFGVLNYNNTEGKIDVRRVIISQAIGGLCFGFFSGQXXXXXXXXXXXXXFVKIISSICNDYDLDFFAMYSCVGLINSLLLILYAMFDISKLMRWSTRSSEEIFALFVAISFVVDAVKDIYK-------------EFSTHYFSCYLSANNQSTEHLRLSRFKRAFSGIISNIXXXXXXXXXXXXXXXXXXCQR------EVSILYLFLVAGTVWLAIQLFTSTKTPFLNNAKREMLTDFALPLAVVIMSLIGTYL-FKEIEMQ-P--FVIVEEKVKFEASGILKLPWLAIAGAIALAFPLSLLMFMDQNISSAMVNSPANKLKKGSSYHWDLLVVALINAGLSVFGLPLVHGALPHSPLHVKALADLEERIDTAHHVHQTIVKVRETRITSILSHVFIGISLQMLPIPLIYIPVAVLDGLFVYMAVTTLYGNQFFERILLLFTEQSAYPPSHYLRRVPQRKLHIFTGLQIFQLAGLCLLGFSPSPYLKMGFPLLLLFHMVFRHQVVPRVIDEKYLNALD 2854
G++ D K++ P + DFRD F + +++ +FLY AC+ P I FG L TEG+I + ++ G+ + F GQPL IL +T P+ +F KI+ C +Y L + ++ + +GL + L I+ D S L+ + TR +EE FA + I F+ +A++ +++ E T Y + ++ S + L+ R + I ++++++ Y +C +V + L TV ++ L + + R +++DFA+ L ++ M LI + ++Q P F + + + + PW I AI A ++L+FMDQ I++ ++N +KLKKG YH DLL+VA++ S+ GLP A S HV +L LE +A + +RE R+T ++ + +G S+ M I L +IP+ VL G+F+YM ++L G Q F+RI L + P YLR VP RK+H+FT +Q+ L L ++ S + + FP+++L +VF +++ + ++ L+ LD
Sbjct: 454 GGLILDIKRKAPFFWSDFRDAFS-----LQCLASFLFLYCACMSPVITFGGLLGEATEGRISAIESLFGASMTGIAYSLFGGQPLTILGSTGPVLVFEKILFKFCKEYGLSYLSLRASIGLWTATLCIILVATDASSLVCYITRFTEEAFASLICIIFIYEALEKLFELSETYPINMHNDLELLTQYSCNCMEPHSPSNDTLKEWRESNLSASDIIWGNLTVSECRSLHGEYVGRACGHGHPYVPDVLFWSVILFFSTVTMSATLKQFKTSRYFPTKVRSIVSDFAVFLTILCMVLIDYAIGIPSPKLQVPSVFKPTRDDRGWFVTPLGPNPWWTIIAAIIPALLCTILIFMDQQITAVIINRKEHKLKKGCGYHLDLLMVAVMLGVCSIMGLPWFVAATVLSITHVNSLK-LESEC-SAPGEQPKFLGIREQRVTGLMIFILMGSSVFMTSI-LKFIPMPVLYGVFLYMGASSLKGIQLFDRIKLFWMPAKHQPDFIYLRHVPLRKVHLFTVIQMSCLGLLWIIKVSRAAIV---FPMMVL-ALVFVRKLMDFLFTKRELSWLD 1006
BLAST of slc4a-8 vs. UniProt/SwissProt
Match: sp|Q8NBS3|S4A11_HUMAN (Sodium bicarbonate transporter-like protein 11 OS=Homo sapiens OX=9606 GN=SLC4A11 PE=1 SV=2) HSP 1 Score: 571.622 bits (1472), Expect = 0.000e+0 Identity = 344/822 (41.85%), Postives = 524/822 (63.75%), Query Frame = 2
Query: 449 NMSNISGSTLAYCLQ-----NADETEDDSVP--CLFLSRLEK-IPMKDFSAEVRATLDIQKFLKEAVLLLDMSGSCLEEIIDSMLLTILAN-EVTDAKVSLEALVEEAKKTLFIQS-SYLTYTYQRLAKTIRGLSLSETEGLMTDQSWLCTMCSLNCIHKRHVAIARLNNPVNMGRSSEGIYFIILVVTPTKEKGTKSDIELGRTFATIFADVEFRQQLLFSESVEQFKELLQYHSGDLMEDQAMNRRKSLKVQEVMNQAFHFD------KKYL-VGSGIVSDFKKRFPVYLMDFRDGFRGKG-TIRKVISATIFLYFACLLPSIAFGVLNYNNTEGKIDVRRVIISQAIGGLCFGFFSGQXXXXXXXXXXXXXFVKIISSICNDYDLDFFAMYSCVGLINSLLLILYAMFDISKLMRWSTRSSEEIFALFVAISFVVDAVKDIYKEFSTHYFSCYLSA--NNQSTEHLRLSRFKRAFSGIISNIXXXXXXXXXXXXXXXXXXCQREVSILYLFLVAGTVWLAIQLFTSTKTPFLNNAKREMLTDFALPLAVVIMSLIGTYLFKEIEMQPFVIVEEKVKFEASGILKLPWLAIAGAIALAFPLSLLMFMDQNISSAMVNSPANKLKKGSSYHWDLLVVALINAGLSVFGLPLVHGALPHSPLHVKALADLEERIDTAHHVHQTIVKVRETRITSILSHVFIGISLQMLPIPLIYIPVAVLDGLFVYMAVTTLYGNQFFERILLLFTEQSAYPPSHYLRRVPQRKLHIFTGLQIFQLAGLCLLGFSPSPYLKMGFPLLLLFHMVFRHQVVPRVIDEKYLNALD 2854
N S +SG ++ + + A TE+++ C+ L K + +K+F E+RA D+ FL +A ++L+ + + L+ ++ +ML + + + +L+ L+ LF + + + L+ TI+G++ + T G+ QSWLC +C++ + KRHV I+RL P N G +S + F+ILV+ P K K TK+ +E+ RTFAT+F+D+ FRQ+LL + + E+FKE L + L K + ++ H K ++ G GI D +RFP+Y +DF DG GK + K I+ T+FLYFACLLP+IAFG LN NT+G IDV++ I Q+IGGL + FSGQPL+ILLTTAPLAL++++I IC+DYDLDF + Y+ GL NS L LYA F++S +M RS+EEI ALF++I+FV+DAVK K F +Y+ YL +++ + LS + + + + + +++S Q ++L L ++ GT+WL L+ K+P+L+ RE+L+D ALP+AV+ SLI ++ F+EIEM F + F + I L A++GA+ L F LS+L F++QN+ +A+VN+P N+L KG++YHWDLL++A+IN GLS+FGLP +H A PHSPLHV+ALA +EER++ H++ TIV V+ETR+TS+ + V +G+SL +LP+PL +IP VL GLF+Y+A+T+L GNQ +R+ LL EQ+AYPP+HY+RRVPQRK+H FTGLQ+ QL LC G S PY+KM FPL+++ + R+ ++PR+I+ KYL+ +D
Sbjct: 72 NSSIVSGESIRFFVNVNLEMQATNTENEATSGGCVLLHTSRKYLKLKNFKEEIRAHRDLDGFLAQASIVLNETATSLDNVLRTMLRRFARDPDNNEPNCNLDLLM----AMLFTDAGAPMRGKVHLLSDTIQGVTATVT-GVRYQQSWLCIICTMKALQKRHVCISRLVRPQNWGENSCEVRFVILVLAPPKMKSTKTAMEVARTFATMFSDIAFRQKLLETRTEEEFKEALVHQRQLLTMVSHGPVAPRTKERSTVSLPAHRHPEPPKCKDFVPFGKGIREDIARRFPLYPLDFTDGIIGKNKAVGKYITTTLFLYFACLLPTIAFGSLNDENTDGAIDVQKTIAGQSIGGLLYALFSGQPLVILLTTAPLALYIQVIRVICDDYDLDFNSFYAWTGLWNSFFLALYAFFNLSLVMSLFKRSTEEIIALFISITFVLDAVKGTVKIFWKYYYGHYLDDYHTKRTSSLVSLSGLGASLNASLHTALNASFLASPTELPSATHSGQ-ATAVLSLLIMLGTLWLGYTLYQFKKSPYLHPCVREILSDCALPIAVLAFSLISSHGFREIEMSKFRYNPSESPFAMAQIQSLSLRAVSGAMGLGFLLSMLFFIEQNLVAALVNAPENRLVKGTAYHWDLLLLAIINTGLSLFGLPWIHAAYPHSPLHVRALALVEERVENG-HIYDTIVNVKETRLTSLGASVLVGLSLLLLPVPLQWIPKPVLYGLFLYIALTSLDGNQLVQRVALLLKEQTAYPPTHYIRRVPQRKIHYFTGLQVLQLLLLCAFGMSSLPYMKMIFPLIMIAMIPIRYILLPRIIEAKYLDVMD 886
BLAST of slc4a-8 vs. UniProt/SwissProt
Match: sp|A2AJN7|S4A11_MOUSE (Sodium bicarbonate transporter-like protein 11 OS=Mus musculus OX=10090 GN=Slc4a11 PE=2 SV=1) HSP 1 Score: 563.148 bits (1450), Expect = 0.000e+0 Identity = 350/822 (42.58%), Postives = 516/822 (62.77%), Query Frame = 2
Query: 449 NMSNISGSTLAYCLQ-------NADETEDDSVPCLFLSRLEK-IPMKDFSAEVRATLDIQKFLKEAVLLLDMSGSCLEEIIDSMLLTIL-----ANEVTDAKVSLEALVEEAKKTLFIQSSYLTYTYQRLAKTIRGLSLSETEGLMTDQSWLCTMCSLNCIHKRHVAIARLNNPVNMGRSSEGIYFIILVVTPTKEKGTKSDIELGRTFATIFADVEFRQQLLFSESVEQFKELLQYHSGDL---MEDQAMNRRKSLKVQEVMNQAFHFDKKYLVGSGIVSDFKKRFPVYLMDFRDGFRGKG-TIRKVISATIFLYFACLLPSIAFGVLNYNNTEGKIDVRRVIISQAIGGLCFGFFSGQXXXXXXXXXXXXXFVKIISSICNDYDLDFFAMYSCVGLINSLLLILYAMFDISKLMRWSTRSSEEIFALFVAISFVVDAVKDIYKEFSTHYFSCYLSANNQSTEHLRLSRFKRAFSGIISNIXXXXXXXXXXXXXXXX---XXCQREVSILYLFLVAGTVWLAIQLFTSTKTPFLNNAKREMLTDFALPLAVVIMSLIGTYLFKEIEMQPFVIVEEKVKFEASGILKLPWLAIAGAIALAFPLSLLMFMDQNISSAMVNSPANKLKKGSSYHWDLLVVALINAGLSVFGLPLVHGALPHSPLHVKALADLEERIDTAHHVHQTIVKVRETRITSILSHVFIGISLQMLPIPLIYIPVAVLDGLFVYMAVTTLYGNQFFERILLLFTEQSAYPPSHYLRRVPQRKLHIFTGLQIFQLAGLCLLGFSPSPYLKMGFPLLLLFHMVFRHQVVPRVIDEKYLNALD 2854
N S +SG ++ + + + + E + C+ L K + +K+F EVRA D+ FL +A ++L+ + + L++++ +ML A D + + L +A + + L+ T Q + T+RG+ +QSWLC +C++ + KRHV I+RL P N G +S + F+ILV+ P K K TK+ +E+ RTFAT+F+D+ FRQ+LL + + E+FKE L + L M A + SL Q + G GI D +RFPVY MDF DG GK ++ K ++ T+FLYFACLLP+IAFG LN NT G IDV++ I Q+IGGL + FSGQPL+ILLTTAPLA++ ++I IC+DY+LDF A Y+ GL NS L LYA ++S LM RS+EEI ALF++I+FV+DAVK + K F +Y+ + S+ L + S + + ++ SL + + + SS + ++L L ++ GT+WL L+ K+P+L+ RE L+D ALP+AV+ SLIG+Y F+EIEM F + FE + I L + AI A+ L F LSLL F++QN+ +A+VN+P N+L KG++YHWDLL++A+IN GLS+FGLP +H A PHSPLHV+ALA +EER++ H+++TIV V+ETR+T++ + V +G+SL +LP PL +IP VL GLF+Y+A+T+L GNQ F R+ LL EQ++YPP+HY+RRVPQRK+H FTGLQI QL LC G S PY+KM FPL+++ + R+ ++PR+I+ KYL+ +D
Sbjct: 46 NSSIVSGESIRFFVNVNLEVQPSKSDLEAATGGCVLLHTSRKYLKLKNFEEEVRAHRDLDGFLAQASIILNETATSLDDVLRTMLNRFALDPNHAEPDCDLDLLMAKLFTDAGAPMESKVHLLSDTIQGVTATVRGVQY--------EQSWLCIICTMKTLQKRHVCISRLVRPQNWGENSCEVRFVILVLAPPKMKSTKTAMEVARTFATMFSDITFRQKLLKTRTEEEFKEALVHQRQLLTMMMPRAAGHSMSSLHTHR-HPQPPKCKDFFPFGKGIWMDIMRRFPVYPMDFTDGIIGKSKSVGKYVTTTLFLYFACLLPTIAFGSLNDENTNGAIDVQKTIAGQSIGGLLYALFSGQPLVILLTTAPLAIYTQVIRVICDDYNLDFNAFYAWTGLWNSFFLALYAFLNLSLLMNLFKRSTEEIIALFISITFVLDAVKGMVKIFGKYYYGHHYHTKRTSSLVSLLGIGRSPNSSLHTALNASLLASPVEMATTSSPGSTHSGQATAVLSLLIMLGTLWLGYTLYQFKKSPYLHPCVRETLSDCALPIAVLSFSLIGSYGFQEIEMSKFRYNPSESLFEVAQIHSLSFKAIGSAMGLGFLLSLLFFIEQNLVAALVNAPENRLVKGTAYHWDLLLLAIINTGLSLFGLPWIHAAYPHSPLHVRALALVEERVENG-HIYETIVDVKETRLTALGASVLVGLSLLLLPFPLQWIPKPVLYGLFLYIALTSLDGNQLFSRVALLLKEQTSYPPTHYIRRVPQRKIHYFTGLQILQLLLLCAFGMSSLPYMKMVFPLIMIAMIPIRYNLLPRIIEAKYLDVMD 857
BLAST of slc4a-8 vs. UniProt/SwissProt
Match: sp|Q2Y0W8|S4A8_HUMAN (Electroneutral sodium bicarbonate exchanger 1 OS=Homo sapiens OX=9606 GN=SLC4A8 PE=1 SV=1) HSP 1 Score: 206.068 bits (523), Expect = 3.652e-53 Identity = 171/565 (30.27%), Postives = 279/565 (49.38%), Query Frame = 2
Query: 1229 SGIVSDFKKRFPVYLMDFRDGFRGKGTIRKVISATIFLYFACLLPSIAFGVLNYNNTEGKIDVRRVIISQAIGGLCFGFFSGQXXXXXXXXXXXXXFVKIISSICNDYDLDFFAMYSCVGLINSLLLILYAMFDISKLMRWSTRSSEEIFALFVAISFVVDAVKDI--------------YKEFSTHYFSCYL--SANNQSTEHLRLSRFKRA---FSGIISNIXXXXXXXXXXXXXXXXXXCQREVSILYLFLVAGTVWLAIQLFTSTKTPFLNNAKREMLTDFALPLA----VVIMSLIGTYLFKEIEMQPFVIVEEKVKFEASGILKLPWLAIAGAIALAFPLSLLMFMDQNISSAMVNSPANKLKKGSSYHWDLLVVALINAGLSVFGLPLVHGALPHSPLHVKALADLEERIDTAHHVHQTIVKVRETRITSILSHVFIGISLQMLPIPLIYIPVAVLDGLFVYMAVTTLYGNQFFERILLLFTEQSAYPPSHYLRRVPQRKLHIFTGLQIFQLAGLCLLGFSPSPYLKMGFPLLLLFHMVFRHQVVPRVIDEKYLNALD 2854
G+V D K++ P Y D+RD + +++ +FLY AC+ P I FG L TEG+I + ++ G+ + F+GQ L IL +T P+ +F KI+ C DY L + ++ +C+GL + L I+ D S L+ + TR +EE FA + I F+ +A++ + S +Y C L + NN + ++ + A ++ + + + + S+ +V L T L+ L T + + R M++DFA+ L V+I LIG K F + + + I PW + AI A ++L+FMDQ I++ ++N +KLKKG YH DLL+VA++ S+ GLP A S HV +L LE +A + +RE R+T ++ V +G S+ M I L +IP+ VL G+F+YM V++L G QFF+R+ L P YLR VP RK+H+FT +Q+ L L ++ SP+ + FP+++L +VF +V+ ++ L+ LD
Sbjct: 453 GGLVLDIKRKAPWYWSDYRDALS-----LQCLASFLFLYCACMSPVITFGGLLGEATEGRISAIESLFGASMTGIAYSLFAGQALTILGSTGPVLVFEKILFKFCKDYALSYLSLRACIGLWTAFLCIVLVATDASSLVCYITRFTEEAFASLICIIFIYEAIEKLIHLAETYPIHMHSQLDHLSLYYCRCTLPENPNNHTLQYWKDHNIVTAEVHWANLTVSECQEMHGEFMGSACGHHGPYTPDVLFWSCILFFTTFILSSTLKTFKTSRYFPTRVRSMVSDFAVFLTIFTMVIIDFLIGVPSPKLQVPSVFKPTRDDRGWIINPIGPNPWWTVIAAIIPALLCTILIFMDQQITAVIINRKEHKLKKGCGYHLDLLMVAIMLGVCSIMGLPWFVAATVLSITHVNSLK-LESEC-SAPGEQPKFLGIREQRVTGLMIFVLMGCSVFMTAI-LKFIPMPVLYGVFLYMGVSSLQGIQFFDRLKLFGMPAKHQPDFIYLRHVPLRKVHLFTLIQLTCLVLLWVIKASPAAIV---FPMMVLA-LVFVRKVMDLCFSKRELSWLD 1005
BLAST of slc4a-8 vs. UniProt/SwissProt
Match: sp|P02730|B3AT_HUMAN (Band 3 anion transport protein OS=Homo sapiens OX=9606 GN=SLC4A1 PE=1 SV=3) HSP 1 Score: 202.986 bits (515), Expect = 1.613e-52 Identity = 160/553 (28.93%), Postives = 276/553 (49.91%), Query Frame = 2
Query: 1229 SGIVSDFKKRFPVYLMDFRDGFRGKGTIRKVISATIFLYFACLLPSIAFGVLNYNNTEGKIDVRRVIISQAIGGLCFGFFSGQXXXXXXXXXXXXXFVKIISSICNDYDLDFFAMYSCVGLINSLLLILYAMFDISKLMRWSTRSSEEIFALFVAISFVVDAVKDIYKEFSTHYFSCYLSANNQSTEHLRLSRFKRAFSGIISNIXXXXXXXXXXXXXXXXXXCQREVSILYLFLVAGTVWLAIQLFTSTKTPFLNNAKREMLTDFALPLAVVIMSLIGTYLFKEIEMQPFVIVE--EKVKFEASGILKLP---------WLAIAGAIALAFPLSLLMFMDQNISSAMVNSPANKLKKGSSYHWDLLVVALINAGLSVFGLPLVHGALPHSPLHVKALADLEERIDTAHHVHQTIVKVRETRITSILSHVFIGISLQMLPIPLIYIPVAVLDGLFVYMAVTTLYGNQFFERILLLFTEQSAYPPSHYLRRVPQRKLHIFTGLQIFQLAGLCLLGFSPSPYLKMGFPLLLLFHMVFRHQVVPRVIDEKYLNALD 2854
G+V D ++R+P YL D D F +V++A IF+YFA L P+I FG L T ++ V ++IS A+ G+ F QPL+++ + PL +F + S C L++ +G LL++L F+ S L+R+ +R ++EIF+ +++ F+ + + K F H Q T + + + G + N ++L L L+AGT + A+ L + + R ++ DF +P++++IM L+ + ++ Q + + + A G + P W+ A A+ A + +L+F++ I++ +V+ P K+ KGS +H DLL+V + ++FG+P + S H AL + + T Q I +V+E RI+ +L V +G+S+ M PI L IP+AVL G+F+YM VT+L G Q F+RILLLF +P Y++RV ++H+FTG+QI LA L ++ +P+ + P +L+ + R ++P + L LD
Sbjct: 380 GGLVRDIRRRYPYYLSDITDAFS-----PQVLAAVIFIYFAALSPAITFGGLLGEKTRNQMGVSELLISTAVQGILFALLGAQPLLVVGFSGPLLVFEEAFFSFCETNGLEYIVGRVWIGFWLILLVVLVVAFEGSFLVRFISRYTQEIFSFLISLIFIYETFSKLIKIFQDHPL--------QKTYNYNVLMVPKP-QGPLPN-----------------------TALLSLVLMAGTFFFAMMLRKFKNSSYFPGKLRRVIGDFGVPISILIMVLV-DFFIQDTYTQKLSVPDGFKVSNSSARGWVIHPLGLRSEFPIWMMFASALP-ALLVFILIFLESQITTLIVSKPERKMVKGSGFHLDLLLVVGMGGVAALFGMPWLSATTVRSVTHANALTVMG-KASTPGAAAQ-IQEVKEQRISGLLVAVLVGLSILMEPI-LSRIPLAVLFGIFLYMGVTSLSGIQLFDRILLLFKPPKYHPDVPYVKRVKTWRMHLFTGIQIICLAVLWVVKSTPA---SLALPFVLILTVPLRRVLLPLIFRNVELQCLD 887
BLAST of slc4a-8 vs. UniProt/SwissProt
Match: sp|P04919|B3AT_MOUSE (Band 3 anion transport protein OS=Mus musculus OX=10090 GN=Slc4a1 PE=1 SV=1) HSP 1 Score: 202.601 bits (514), Expect = 2.276e-52 Identity = 159/559 (28.44%), Postives = 277/559 (49.55%), Query Frame = 2
Query: 1229 SGIVSDFKKRFPVYLMDFRDGFRGKGTIRKVISATIFLYFACLLPSIAFGVLNYNNTEGKIDVRRVIISQAIGGLCFGFFSGQXXXXXXXXXXXXXFVKIISSICNDYDLDFFAMYSCVGLINSLLLILYAMFDISKLMRWSTRSSEEIFALFVAISFVVDAVKDIYKEFSTHYFSCYLSANNQSTEHLRLSRFKRAFSGIISNIXXXXXXXXXXXXXXXXXXCQREVSILYLFLVAGTVWLAIQLFTSTKTPFLNNAKREMLTDFALPLAVVIMSLI-----GTYLFKEIEMQPFVIVEEKVKFEAS----------GILKL--PWLAIAGAIALAFPLSLLMFMDQNISSAMVNSPANKLKKGSSYHWDLLVVALINAGLSVFGLPLVHGALPHSPLHVKALADLEERIDTAHHVHQTIVKVRETRITSILSHVFIGISLQMLPIPLIYIPVAVLDGLFVYMAVTTLYGNQFFERILLLFTEQSAYPPSHYLRRVPQRKLHIFTGLQIFQLAGLCLLGFSPSPYLKMGFPLLLLFHMVFRHQVVPRVIDEKYLNALD 2854
G++ D ++R+P YL D D +V++A IF+YFA L P++ FG L T + V ++IS A+ G+ F QPL++L + PL +F + S C +L++ + +G LL++L F+ S L+++ +R ++EIF+ +++ F+ + + K F + Q T + + K G + N ++ L L+AGT LA+ L + + R ++ DF +P++++IM L+ GTY K + V + +K S G+ +L W+ A + A + +L+F++ I++ +V+ P K+ KGS +H DLL+V + ++FG+P + S H AL + + + I +V+E RI+ +L V +G+S+ M PI L IP+AVL G+F+YM VT+L G Q F+RILLLF +P +++RV ++H+FTG+QI LA L ++ +P+ + P +L+ + R ++P + E L LD
Sbjct: 399 GGLIRDIRRRYPYYLSDITDALS-----PQVLAAVIFIYFAALSPAVTFGGLLGEKTRNLMGVSELLISTAVQGILFALLGAQPLLVLGFSGPLLVFEEAFFSFCESNNLEYIVGRAWIGFWLILLVMLVVAFEGSFLVQYISRYTQEIFSFLISLIFIYETFSKLIKIFQDYPL--------QQTYAPVVMKPKP--QGPVPN-----------------------TALFSLVLMAGTFLLAMTLRKFKNSTYFPGKLRRVIGDFGVPISILIMVLVDSFIKGTYTQK-------LSVPDGLKVSNSSARGWVIHPLGLYRLFPTWMMFASVLP-ALLVFILIFLESQITTLIVSKPERKMIKGSGFHLDLLLVVGMGGVAALFGMPWLSATTVRSVTHANALTVMGKA--SGPGAAAQIQEVKEQRISGLLVSVLVGLSILMEPI-LSRIPLAVLFGIFLYMGVTSLSGIQLFDRILLLFKPPKYHPDVPFVKRVKTWRMHLFTGIQIICLAVLWVVKSTPA---SLALPFVLILTVPLRRLILPLIFRELELQCLD 905
BLAST of slc4a-8 vs. TrEMBL
Match: A0A0H3YK00 (Slc4a-8 OS=Schmidtea mediterranea OX=79327 GN=slc4a-8 PE=2 SV=1) HSP 1 Score: 1701.8 bits (4406), Expect = 0.000e+0 Identity = 915/915 (100.00%), Postives = 915/915 (100.00%), Query Frame = 2
Query: 119 MSDSDLGIQTSLEEIPLKCNLKRISXXXXXXXXXXDTVGHNIYSSRRPSSLHQTTFSGRNYYSMPTGEQEVTIKDNRTSISSHLFXXXXXXXXXXXXXXXXXXASNVSVDNMSNISGSTLAYCLQNADETEDDSVPCLFLSRLEKIPMKDFSAEVRATLDIQKFLKEAVLLLDMSGSCLEEIIDSMLLTILANEVTDAKVSLEALVEEAKKTLFIQSSYLTYTYQRLAKTIRGLSLSETEGLMTDQSWLCTMCSLNCIHKRHVAIARLNNPVNMGRSSEGIYFIILVVTPTKEKGTKSDIELGRTFATIFADVEFRQQLLFSESVEQFKELLQYHSGDLMEDQAMNRRKSLKVQEVMNQAFHFDKKYLVGSGIVSDFKKRFPVYLMDFRDGFRGKGTIRKVISATIFLYFACLLPSIAFGVLNYNNTEGKIDVRRVIISQAIGGLCFGFFSGQXXXXXXXXXXXXXFVKIISSICNDYDLDFFAMYSCVGLINSLLLILYAMFDISKLMRWSTRSSEEIFALFVAISFVVDAVKDIYKEFSTHYFSCYLSANNQSTEHLRLSRFKRAFSGIISNIXXXXXXXXXXXXXXXXXXCQREVSILYLFLVAGTVWLAIQLFTSTKTPFLNNAKREMLTDFALPLAVVIMSLIGTYLFKEIEMQPFVIVEEKVKFEASGILKLPWLAIAGAIALAFPLSLLMFMDQNISSAMVNSPANKLKKGSSYHWDLLVVALINAGLSVFGLPLVHGALPHSPLHVKALADLEERIDTAHHVHQTIVKVRETRITSILSHVFIGISLQMLPIPLIYIPVAVLDGLFVYMAVTTLYGNQFFERILLLFTEQSAYPPSHYLRRVPQRKLHIFTGLQIFQLAGLCLLGFSPSPYLKMGFPLLLLFHMVFRHQVVPRVIDEKYLNALDKPI 2863
MSDSDLGIQTSLEEIPLKCNLKRISNEINNHNHEIDTVGHNIYSSRRPSSLHQTTFSGRNYYSMPTGEQEVTIKDNRTSISSHLFLLPPSPGRRLSRQRQGSSASNVSVDNMSNISGSTLAYCLQNADETEDDSVPCLFLSRLEKIPMKDFSAEVRATLDIQKFLKEAVLLLDMSGSCLEEIIDSMLLTILANEVTDAKVSLEALVEEAKKTLFIQSSYLTYTYQRLAKTIRGLSLSETEGLMTDQSWLCTMCSLNCIHKRHVAIARLNNPVNMGRSSEGIYFIILVVTPTKEKGTKSDIELGRTFATIFADVEFRQQLLFSESVEQFKELLQYHSGDLMEDQAMNRRKSLKVQEVMNQAFHFDKKYLVGSGIVSDFKKRFPVYLMDFRDGFRGKGTIRKVISATIFLYFACLLPSIAFGVLNYNNTEGKIDVRRVIISQAIGGLCFGFFSGQPLIILLTTAPLALFVKIISSICNDYDLDFFAMYSCVGLINSLLLILYAMFDISKLMRWSTRSSEEIFALFVAISFVVDAVKDIYKEFSTHYFSCYLSANNQSTEHLRLSRFKRAFSGIISNISISLTQTNLNSSLYSSNSCQREVSILYLFLVAGTVWLAIQLFTSTKTPFLNNAKREMLTDFALPLAVVIMSLIGTYLFKEIEMQPFVIVEEKVKFEASGILKLPWLAIAGAIALAFPLSLLMFMDQNISSAMVNSPANKLKKGSSYHWDLLVVALINAGLSVFGLPLVHGALPHSPLHVKALADLEERIDTAHHVHQTIVKVRETRITSILSHVFIGISLQMLPIPLIYIPVAVLDGLFVYMAVTTLYGNQFFERILLLFTEQSAYPPSHYLRRVPQRKLHIFTGLQIFQLAGLCLLGFSPSPYLKMGFPLLLLFHMVFRHQVVPRVIDEKYLNALDKPI
Sbjct: 1 MSDSDLGIQTSLEEIPLKCNLKRISNEINNHNHEIDTVGHNIYSSRRPSSLHQTTFSGRNYYSMPTGEQEVTIKDNRTSISSHLFLLPPSPGRRLSRQRQGSSASNVSVDNMSNISGSTLAYCLQNADETEDDSVPCLFLSRLEKIPMKDFSAEVRATLDIQKFLKEAVLLLDMSGSCLEEIIDSMLLTILANEVTDAKVSLEALVEEAKKTLFIQSSYLTYTYQRLAKTIRGLSLSETEGLMTDQSWLCTMCSLNCIHKRHVAIARLNNPVNMGRSSEGIYFIILVVTPTKEKGTKSDIELGRTFATIFADVEFRQQLLFSESVEQFKELLQYHSGDLMEDQAMNRRKSLKVQEVMNQAFHFDKKYLVGSGIVSDFKKRFPVYLMDFRDGFRGKGTIRKVISATIFLYFACLLPSIAFGVLNYNNTEGKIDVRRVIISQAIGGLCFGFFSGQPLIILLTTAPLALFVKIISSICNDYDLDFFAMYSCVGLINSLLLILYAMFDISKLMRWSTRSSEEIFALFVAISFVVDAVKDIYKEFSTHYFSCYLSANNQSTEHLRLSRFKRAFSGIISNISISLTQTNLNSSLYSSNSCQREVSILYLFLVAGTVWLAIQLFTSTKTPFLNNAKREMLTDFALPLAVVIMSLIGTYLFKEIEMQPFVIVEEKVKFEASGILKLPWLAIAGAIALAFPLSLLMFMDQNISSAMVNSPANKLKKGSSYHWDLLVVALINAGLSVFGLPLVHGALPHSPLHVKALADLEERIDTAHHVHQTIVKVRETRITSILSHVFIGISLQMLPIPLIYIPVAVLDGLFVYMAVTTLYGNQFFERILLLFTEQSAYPPSHYLRRVPQRKLHIFTGLQIFQLAGLCLLGFSPSPYLKMGFPLLLLFHMVFRHQVVPRVIDEKYLNALDKPI 915
BLAST of slc4a-8 vs. TrEMBL
Match: A0A0H3YIT6 (Slc4a-5 OS=Schmidtea mediterranea OX=79327 GN=slc4a-5 PE=2 SV=1) HSP 1 Score: 947.577 bits (2448), Expect = 0.000e+0 Identity = 476/804 (59.20%), Postives = 612/804 (76.12%), Query Frame = 2
Query: 446 DNMSNISGSTLAYCLQNADETEDDSVPCLFLSRLEKIPMKDFSAEVRATLDIQKFLKEAVLLLDMSGSCLEEIIDSMLLTILANEVTDAKVSLEALVEEAKKTLFIQSSYLTYTYQRLAKTIRGLSLSETEGLMTDQSWLCTMCSLNCIHKRHVAIARLNNPVNMGRSSEGIYFIILVVTPTKEKGTKSDIELGRTFATIFADVEFRQQLLFSESVEQFKELLQYHSGDLMEDQAMNRRKSLKVQEVMNQAFHFDKKYLVGSGIVSDFKKRFPVYLMDFRDGFRGKGTIRKVISATIFLYFACLLPSIAFGVLNYNNTEGKIDVRRVIISQAIGGLCFGFFSGQXXXXXXXXXXXXXFVKIISSICNDYDLDFFAMYSCVGLINSLLLILYAMFDISKLMRWSTRSSEEIFALFVAISFVVDAVKDIYKEFSTHYFSCYLSANNQSTEHLRLSRFKRAFSGIISNIXXXXXXXXXXXXXXXXXXCQREVSILYLFLVAGTVWLAIQLFTSTKTPFLNNAKREMLTDFALPLAVVIMSLIGTYLFKEIEMQPFVIVEEKVKFEASGILKLPWLAIAGAIALAFPLSLLMFMDQNISSAMVNSPANKLKKGSSYHWDLLVVALINAGLSVFGLPLVHGALPHSPLHVKALADLEERIDTAHHVHQTIVKVRETRITSILSHVFIGISLQMLPIPLIYIPVAVLDGLFVYMAVTTLYGNQFFERILLLFTEQSAYPPSHYLRRVPQRKLHIFTGLQIFQLAGLCLLGFSPSPYLKMGFPLLLLFHMVFRHQVVPRVIDEKYLNALDK 2857
DN+S +SG + L+N + P L LSRLEK+P+KDFS+EVRA+LDI+KF+KE+VL L+M +EEII+ ML+ IL E+TD ++SLE ++EAK LF+ +S+LTY+YQRLAKTI+G+S+ +TEGL DQSW+ M +L +HKRH+AIARL+ P N+GRS+E ++FIILV+ PTKEKGTKS+IELGRTF+TI AD++FRQQLL E+ + F+ +LQ+ + L E Q + R++S+KV EVM+QAF K+ +G GIV D K+R P YL D+ DGF+G TIRKV S T FLYF+CLLPSIAFGVLN NNT+ KIDV+RVIISQAIGGL FG GQPLI++LTTAPLAL+ KII +I +Y +DF AM++C G+ N++ L++Y++ D+ KLM+WST+S+EE+FA FVAI+F VDA KD+YKEF+ HY C ++ LS F I S +S N +S C R+VS+LYL L GTVWLA LF TKTP+LN KRE+L DFALPLA+ IMS+IG LF++I + PF E+ +F+ + L W AI AL FPLSLL FMDQNI+S+MVNSP+NKLKKGS++HWDL +VALIN LS+FGLP +HGA+PHSPLHVKAL+D+EERID H VHQTIV+VRETR+TSILS++FI +SL +LP PL YIP+AVLDGLF++MAVT+LY NQF ERI LLFTEQSAYPPSHYLRRVPQRKLH+FT Q+ QL L LGFSPSPY+KMGFP++LL + RH+++P+ IDE ++NA+DK
Sbjct: 77 DNISMLSGVS-GIGLRNLSLFYNSPPPYLVLSRLEKLPLKDFSSEVRASLDIEKFVKESVLFLEMPCLSMEEIIERMLINILECEITD-EISLEMWIKEAKTKLFMHTSFLTYSYQRLAKTIKGISIDDTEGLAMDQSWITAMATLPNLHKRHLAIARLSTPANLGRSNENVHFIILVLNPTKEKGTKSEIELGRTFSTIMADIDFRQQLLMIENEQDFRSMLQFQARQLAETQKILRKRSVKVDEVMDQAFSVKTKFWIGGGIVGDIKRRIPHYLSDYCDGFKGANTIRKVFSTTSFLYFSCLLPSIAFGVLNGNNTDRKIDVKRVIISQAIGGLVFGILGGQPLIVMLTTAPLALYTKIIFTISTEYKIDFSAMFACTGIFNAVYLMIYSLTDMCKLMKWSTKSTEEVFAFFVAIAFTVDASKDVYKEFAQHY-QCAEENKVNNSIFKSLSNMSNPFQ-ITSTLSPMPDFHNSLHKGHSP--CHRDVSVLYLLLTIGTVWLAGHLFNFTKTPYLNARKRELLADFALPLAITIMSIIGALLFRDINLDPFYYDEKVFQFQPVNLPILGWKAILSCAALGFPLSLLFFMDQNIASSMVNSPSNKLKKGSTFHWDLFIVALINGFLSIFGLPWIHGAIPHSPLHVKALSDIEERIDIGHKVHQTIVRVRETRVTSILSNIFIALSLFLLPKPLSYIPIAVLDGLFIHMAVTSLYNNQFCERITLLFTEQSAYPPSHYLRRVPQRKLHLFTFFQLIQLIMLSALGFSPSPYMKMGFPIVLLLQIPIRHKIIPKFIDEIFINAMDK 874
BLAST of slc4a-8 vs. TrEMBL
Match: A0A0H3YEW7 (Slc4a-4 OS=Schmidtea mediterranea OX=79327 GN=slc4a-4 PE=2 SV=1) HSP 1 Score: 907.516 bits (2344), Expect = 0.000e+0 Identity = 460/815 (56.44%), Postives = 623/815 (76.44%), Query Frame = 2
Query: 428 ASNVSVDNMSNISGSTLAYCLQNADETEDDSVPCLFLSRLEKIPMKDFSAEVRATLDIQKFLKEAVLLLDMSGSCLEEIIDSMLLTI--LANEVTDAKVSLEALVEEAKKTLFIQSSYLTYTYQRLAKTIRGLSLSETEGLMTDQSWLCTMCSLNCIHKRHVAIARLNNPVNMGRSSEGIYFIILVVTPTKEKGTKSDIELGRTFATIFADVEFRQQLLFSESVEQFKELLQYHSGDLMEDQAMNRRKSLKVQEVMNQAFHFDKKYLVGSGIVSDFKKRFPVYLMDFRDGFRGKGTIRKVISATIFLYFACLLPSIAFGVLNYNNTEGKIDVRRVIISQAIGGLCFGFFSGQXXXXXXXXXXXXXFVKIISSICNDYDLDFFAMYSCVGLINSLLLILYAMFDISKLMRWSTRSSEEIFALFVAISFVVDAVKDIYKEFSTHYFSCYLSANNQSTEHLRLSRFKRAFSGIISNIXXXXXXXXXXXXXXXXXXCQREVSILYLFLVAGTVWLAIQLFTSTKTPFLNNAKREMLTDFALPLAVVIMSLIGTYLFKEIEMQPFVI-VEEKVKFEASGILKLPWLAIAGAIALAFPLSLLMFMDQNISSAMVNSPANKLKKGSSYHWDLLVVALINAGLSVFGLPLVHGALPHSPLHVKALADLEERIDTAHHVHQTIVKVRETRITSILSHVFIGISLQMLPIPLIYIPVAVLDGLFVYMAVTTLYGNQFFERILLLFTEQSAYPPSHYLRRVPQRKLHIFTGLQIFQLAGLCLLGFSPSPYLKMGFPLLLLFHMVFRHQVVPRVIDEKYLNALDKPI 2863
S +S D +SN S +LA + ADE + +PCL L+RLEKIP+KDFS+EVRATLD++KFLKE VL+LDM + ++ I++ +L I LA +V+ + ++ + EAK LF+++ Y ++YQRLAKT++G+ ++E EGL TDQSW+ MCSL C+HKRHVAIARL PVN+GRSSEG+YF++LV+TP KEK TKSDIEL RTFAT+ +D+EFR QLLF+++ ++FKE+LQ H+ DL E+Q + RR+S+++ EVMNQAF +++K+ +G+GIV D +KR PVY+ D++DG +G GTIRK++SA FLYFACLLPS+AFGVL NT+GKI+V+RVI+SQ +GGLCF GQPLI++LTTAPL L++K+I +I Y L F+ M+S VG+ NS+ LILY++ D+SKLMRWSTRS+EEIFALF++I+F+VDAVKD+ K F Y + + N++ + + K G++++ ++ ++E +L+L L+ GTVWL I TKTPFLN++KR ++ D++LPLAV+IMS IG+YLFK+I++ F EE+ + ++ A+ A+ LAFPLSLL FMDQN++SAMVN P+NKLKKGS+YHWDLL+VA+IN LS+FGLP VHG LPHSPLHVKALADLEERID+ H +++TIVKVRETR+T ++SH+ IG+SL +LPIPLIY+P+AVLDGLFVYMA+T LYGNQ ER++LLFTEQ+AYPPSHYLRRVPQRK+H+FT LQ+ QL LC LGF+P+PY K+GFP+LLL M RH + P+ I Y++ALDKPI
Sbjct: 95 TSEMSTDTVSNFSIGSLARYYRTADE-NGEGLPCLVLARLEKIPIKDFSSEVRATLDVEKFLKEVVLILDMEANDVDTIVEHLLREIYPLAMDVSIGQ--MDTFITEAKNALFMKAHYENFSYQRLAKTLKGILINENEGLSTDQSWISAMCSLTCVHKRHVAIARLKTPVNLGRSSEGVYFVMLVITPKKEKDTKSDIELSRTFATLLSDMEFRSQLLFAQTEDEFKEMLQNHARDLAEEQRLYRRRSIRITEVMNQAFAYEEKFPLGNGIVDDLRKRIPVYISDYKDGIQGPGTIRKLVSAATFLYFACLLPSMAFGVLYDQNTDGKINVKRVILSQTVGGLCFALIGGQPLIVMLTTAPLTLYIKVIYAISAKYSLHFYTMFSWVGIFNSIFLILYSLLDLSKLMRWSTRSTEEIFALFISIAFIVDAVKDVLKVFYKSYVTTLV---NKTVPIVNTTLAK----GLLNS--------TNEFITITTEESRKENGLLFLLLLIGTVWLGIYFLNFTKTPFLNSSKRLLMADYSLPLAVLIMSFIGSYLFKDIKIDTFKTRSEEEFSIKFVNFSQISISAVFAALGLAFPLSLLFFMDQNVTSAMVNCPSNKLKKGSAYHWDLLIVAIINLVLSLFGLPWVHGTLPHSPLHVKALADLEERIDSGHRIYETIVKVRETRLTGLISHILIGLSLLLLPIPLIYVPIAVLDGLFVYMAITALYGNQLVERVILLFTEQAAYPPSHYLRRVPQRKVHLFTVLQLTQLGLLCALGFAPTPYAKIGFPILLLLQMPIRHWIFPKFISLTYIDALDKPI 891
BLAST of slc4a-8 vs. TrEMBL
Match: A0A267G7Q1 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig031769g2 PE=4 SV=1) HSP 1 Score: 894.419 bits (2310), Expect = 0.000e+0 Identity = 468/836 (55.98%), Postives = 614/836 (73.44%), Query Frame = 2
Query: 428 ASNVSVDNMSNISGSTLAYCLQNADETEDDSVPCLFLSRLEKIPMKDFSAEVRATLDIQKFLKEAVLLLDMSGSCLEEIIDSMLLTILANE------------------------VTDAKVSLEALVEEAKKTLFIQSSYLTYTYQRLAKTIRGLSLSETEGLMTDQSWLCTMCSLNCIHKRHVAIARLNNPVNMGRSSEGIYFIILVVTPTKEKGTKSDIELGRTFATIFADVEFRQQLLFSESVEQFKELLQYHSGDLMEDQAMNRRKSLKVQEVMNQAFHFDKKYLVGSGIVSDFKKRFPVYLMDFRDGFRGKGTIRKVISATIFLYFACLLPSIAFGVLNYNNTEGKIDVRRVIISQAIGGLCFGFFSGQXXXXXXXXXXXXXFVKIISSICNDYDLDFFAMYSCVGLINSLLLILYAMFDISKLMRWSTRSSEEIFALFVAISFVVDAVKDIYKEFSTHYFSCYLSANNQSTEHLRLSRFKRAFSGIISNIXXXXXXXXXXXXXXXXXXCQREVSILYLFLVAGTVWLAIQLFTSTKTPFLNNAKREMLTDFALPLAVVIMSLIGTYLFKEIEMQPFVIVEEKVKFEASGILKLPWLAIAGAIALAFPLSLLMFMDQNISSAMVNSPANKLKKGSSYHWDLLVVALINAGLSVFGLPLVHGALPHSPLHVKALADLEERIDTAHHVHQTIVKVRETRITSILSHVFIGISLQMLPIPLIYIPVAVLDGLFVYMAVTTLYGNQFFERILLLFTEQSAYPPSHYLRRVPQRKLHIFTGLQIFQLAGLCLLGFSPSPYLKMGFPLLLLFHMVFRHQVVPRVIDEKYLNALDKPI 2863
A++V DN+S +SG +LA +NAD T D+S+PCL +SRLEKIP+KDFS+E+RA +DIQ+FLKEA LLLD+ G+ +E II+ ML +I + D++ L+A V++AKKTLF+Q++++ YTYQRLAKTI+ +S+ ++EGL+TD SWLCTMCSLN + KRHVAIARL+ PVN+GRSSEG+ FI+LVVTPTKEKGTKSDIELGRTFATI AD EFRQ+LL +E+ +FKE+LQ H+ +L E+Q + RRKSL+ ++ M+QAF+++ + + +GI +D K+R YL DF D FR TIRKV++ IFLYFACL+P IAFGVLN + T G I V RVI+SQ IGG+ F F GQPLII+LTTAPLAL+ +II + ++ LDFFA + VG+ N+ LL+LYA+ D+SKLMRWSTRS+EEIFA+F++++F V AVK +Y F T+Y T L+ + ++ + +S +CQR+VSIL+L L GTV+L++ L TKTP+LN AKRE++ DF+LP++V+ MS +GTYLF+ ++++ F + ++ E LP LAI GA LA PLS+L FM+QNISSAMVN PANKL+KGS+YH DLL VAL+N +S FGLP VHGALPHSPLHVKALADLEERID HVHQ++V+VRETRIT ++S+V IG+SL M P+PL +IPV VLDGLFV MA+T L+ NQ FERILLLFTEQ+AYPPSHYLRRVPQRK+HIFT LQ+ QL LC LGF+ Y K+GFP++L M RH ++P++IDE YL+ALDKP+
Sbjct: 100 AASVDRDNLSIMSGGSLAMFYRNADGT-DESLPCLVVSRLEKIPLKDFSSEIRANMDIQRFLKEATLLLDVEGANVECIIEQMLRSIFRADHESHHSSGSGGGGGDGGSVAGAAGAIDSR--LDAKVQDAKKTLFLQANWMDYTYQRLAKTIKSISVVDSEGLITDNSWLCTMCSLNGVQKRHVAIARLSTPVNLGRSSEGVSFILLVVTPTKEKGTKSDIELGRTFATILADSEFRQKLLLAETESEFKEMLQGHAHELGEEQKIYRRKSLRTKDFMSQAFNYESSWPICNGIRADLKRRLSHYLSDFIDAFRDNKTIRKVVTTVIFLYFACLMPCIAFGVLNNSLTNGYITVHRVILSQCIGGVTFALFGGQPLIIMLTTAPLALYTRIIFELSQNHGLDFFAFFGWVGVFNAALLLLYAVLDLSKLMRWSTRSTEEIFAMFISVAFTVGAVKSVYGNFDTYYCD---GNGGAETNGGNLTSGSDKWGPNLT-LDSQSALNGSSSVGQKQQNCQRDVSILFLLLCIGTVFLSMYLLNFTKTPYLNRAKRELMADFSLPVSVLAMSFVGTYLFRNVQLEKFSCL-PYIQLEFVIARPLPGLAILGAFGLAIPLSMLFFMEQNISSAMVNCPANKLRKGSAYHLDLLTVALMNGVMSCFGLPWVHGALPHSPLHVKALADLEERIDLGQHVHQSVVRVRETRITGVVSNVLIGLSLLMCPVPLSFIPVPVLDGLFVCMAITALFDNQLFERILLLFTEQAAYPPSHYLRRVPQRKVHIFTCLQLLQLFVLCALGFNSIAYAKLGFPVILFLQMPVRHLLIPKLIDENYLDALDKPM 927
BLAST of slc4a-8 vs. TrEMBL
Match: A0A267H2A6 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig031769g1 PE=4 SV=1) HSP 1 Score: 892.108 bits (2304), Expect = 0.000e+0 Identity = 467/837 (55.79%), Postives = 612/837 (73.12%), Query Frame = 2
Query: 428 ASNVSVDNMSNISGSTLAYCLQNADETEDDSVPCLFLSRLEKIPMKDFSAEVRATLDIQKFLKEAVLLLDMSGSCLEEIIDSMLLTILANE------------------------VTDAKVSLEALVEEAKKTLFIQSSYLTYTYQRLAKTIRGLSLSETEGLMTDQSWLCTMCSLNCIHKRHVAIARLNNPVNMGRSSEGIYFIILVVTPTKEKGTKSDIELGRTFATIFADVEFRQQLLFSESVEQFKELLQYHSGDLMEDQAMNRRKSLKVQEVMNQAFHFDKKYLVGSGIVSDFKKRFPVYLMDFRDGFRGKGTIRKVISATIFLYFACLLPSIAFGVLNYNNTEGKIDVRRVIISQAIGGLCFGFFSGQXXXXXXXXXXXXXFVKIISSICNDYDLDFFAMYSCVGLINSLLLILYAMFDISKLMRWSTRSSEEIFALFVAISFVVDAVKDIYKEFSTHYFSCYLSANNQSTEHLRLS-RFKRAFSGIISNIXXXXXXXXXXXXXXXXXXCQREVSILYLFLVAGTVWLAIQLFTSTKTPFLNNAKREMLTDFALPLAVVIMSLIGTYLFKEIEMQPFVIVEEKVKFEASGILKLPWLAIAGAIALAFPLSLLMFMDQNISSAMVNSPANKLKKGSSYHWDLLVVALINAGLSVFGLPLVHGALPHSPLHVKALADLEERIDTAHHVHQTIVKVRETRITSILSHVFIGISLQMLPIPLIYIPVAVLDGLFVYMAVTTLYGNQFFERILLLFTEQSAYPPSHYLRRVPQRKLHIFTGLQIFQLAGLCLLGFSPSPYLKMGFPLLLLFHMVFRHQVVPRVIDEKYLNALDKPI 2863
A++V DN+S +SG +LA +NAD T D+S+PCL +SRLEKIP+KDFS+E+RA +DIQ+FLKEA LLLD+ G+ +E II+ ML +I + D++ L+A V++AKKTLF+Q++++ YTYQRLAKTI+ +S+ ++EGL+TD SWLCTMCSLN + KRHVAIARL+ PVN+GRSSEG+ FI+LVVTPTKEKGTKSDIELGRTFATI AD EFRQ+LL +E+ +FKE+LQ H+ +L E+Q + RRKSL+ ++ M+QAF ++ + + +GI +D K+R YL DF D FR TIRKV++ IFLYFACL+P IAFGVLN + T G I V RVI+SQ IGG+ F F GQPLI++LTTAPLAL+ II + ++ LDFFA + VG+ N+ LL+LYA+ D+SKLMRWSTRS+EEIFA+F++++F V AVK +Y F T+Y A S ++ R + + +S +CQR+VSIL+L L GTV+L++ L TKTP+LN AKRE++ DF+LP++V+ MS +GTYLF+ ++++ F + ++ E LP LAI GA LA PLS+L FM+QNISSAMVN PANKL+KGS+YH DLL VAL+N +S FGLP VHGALPHSPLHVKALADLEERID HVHQ++V+VRETRIT ++S++ IG+SL M P+PL +IPV VLDGLFV MA+T L+ NQ FERILLLFTEQ+AYPPSHYLRRVPQRK+HIFT LQ+ QL LC LGF+ Y K+GFP++L M RH ++P++IDE YL+ALDKP+
Sbjct: 100 AASVDRDNLSIMSGGSLAMFYRNADGT-DESLPCLVVSRLEKIPLKDFSSEIRANMDIQRFLKEATLLLDVEGANVECIIEQMLRSIFRADHESHHSSGSGGGGGDGGSVAGAAGAIDSR--LDAKVQDAKKTLFLQANWMDYTYQRLAKTIKSISVVDSEGLITDNSWLCTMCSLNGVQKRHVAIARLSTPVNLGRSSEGVSFILLVVTPTKEKGTKSDIELGRTFATILADSEFRQKLLLAETESEFKEMLQGHAHELGEEQKIYRRKSLRTKDFMSQAFSYESSWPICNGIRADLKRRLSHYLSDFIDAFRDNKTIRKVVTTVIFLYFACLMPCIAFGVLNNSLTNGYITVHRVILSQCIGGVTFALFGGQPLIVMLTTAPLALYTHIIFELSQNHGLDFFAFFGWVGVFNAALLLLYAVLDLSKLMRWSTRSTEEIFAMFISVAFTVGAVKSVYGNFDTYYCDGNGGAETNGGNLTSGSDKWGRNLT-----LDSQSALNGSSSVGQKQQNCQRDVSILFLLLCIGTVFLSMYLLNFTKTPYLNRAKRELMADFSLPVSVLAMSFVGTYLFRNVQLENFSCL-PYIQLEFVIARPLPGLAILGAFGLAIPLSMLFFMEQNISSAMVNCPANKLRKGSAYHLDLLTVALMNGVMSCFGLPWVHGALPHSPLHVKALADLEERIDLGQHVHQSVVRVRETRITGVVSNILIGLSLLMCPVPLSFIPVPVLDGLFVCMAITALFDNQLFERILLLFTEQAAYPPSHYLRRVPQRKVHIFTCLQLLQLFVLCALGFNSIAYAKLGFPVILFLQMPVRHLLIPKLIDENYLDALDKPM 927
BLAST of slc4a-8 vs. Ensembl Cavefish
Match: ENSAMXT00000011908.2 (pep primary_assembly:Astyanax_mexicanus-2.0:APWO02000151.1:229098:263825:-1 gene:ENSAMXG00000011585.2 transcript:ENSAMXT00000011908.2 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 557.37 bits (1435), Expect = 0.000e+0 Identity = 320/775 (41.29%), Postives = 481/775 (62.06%), Query Frame = 2
Query: 560 MKDFSAEVRATLDIQKFLKEAVLLLDMSGSCLEEIIDSMLLTILANEVTDAKVSLEALVEEAKKTLFIQSSYLTYTYQRLAKTIRGLSLSETEGLMTDQSWLCTMCSLNCIHKRHVAIARLNNPVNMGRSSEGIYFIILVVTPTKEKGTKSDIELGRTFATIFADVEFRQQLLFSESVEQFKELLQY---------HSGDLMEDQAMNRRKSLKVQEVMNQAFHFDKKYLVGSGIVSDFKKRFPVYLMDFRDGFRGKG-TIRKVISATIFLYFACLLPSIAFGVLNYNNTEGKIDVRRVIISQAIGGLCFGFFSGQXXXXXXXXXXXXXFVKIISSICNDYDLDFFAMYSCVGLINSLLLILYAMFDISKLMRWSTRSSEEIFALFVAISFVVDAVKDIYKEFSTHYFSCYLSANNQSTEHLRLSRFKRAFSGIISNIXXXXXXXXXXXXXXXXXXCQREVSILYLFLVAGTVWLAIQLFTSTKTPFLNNAKREMLTDFALPLAVVIMSLIGTYLFKEIEMQPFVIVEEKVKFEASGILKLPWLAIAGAIALAFPLSLLMFMDQNISSAMVNSPANKLKKGSSYHWDLLVVALINAGLSVFGLPLVHGALPHSPLHVKALADLEERIDTAHHVHQTIVKVRETRITSILSHVFIGISLQMLPIPLIYIPVAVLDGLFVYMAVTTLYGNQFFERILLLFTEQSAYPPSHYLRRVPQRKLHIFTGLQIFQLAGLCLLGFSPSPYLKMGFPLLLLFHMVFRHQVVPRVIDEKYLNALD 2854
+ +F EVRA D+ FL +A +LLD + + L+E++ ML + D + S + E LF + + L +TI+ ++ + T G+ QSWLC +C++ + +R V I RL P N G + + F+IL++ P + K TK+ IELGRTFAT+F+D+ FRQ+LL +++ + FK+ L + H + E+ + K LKV+E + G GI D +R P Y+ DF DG G ++ K + IFLY A LLP+IAFG LN +T G+IDV++ I+ Q+IGG+ + +G P++I +TTAPLA+F+ +I IC+DYDLDF A Y+C+GL NSL LIL +F+IS M+ RS+EE+ ALF++I+FV DAVK K F +Y L N+ + E L+ + S + + S C RE IL L L+ GT+WL LF ++PFL+ RE+++D ALP++VVI S +G+YLF +IE+ F + F + + L + + A L F L+LL+F+DQNI ++ N+P N+L KG++YHWDL++ IN +SV GLP +H A PHS LHV+ LA +E+R++ H +++TIV V+ETR+TS+ ++V IG+S+ +LP+PL +IP VL GLF+Y+A+T++ GNQ +RI LL EQ++YPP+HY+RRVPQRK+H FTGLQ+ QL LC G P PY+KM FPLL++F + R+ ++P++I+ KYL+ +D
Sbjct: 42 LMNFQEEVRAHRDLNSFLAQASILLDETAASLDEVLRRMLQHV----ARDGQGSCDQ--REVISALFTDAGGQEASVHLLTETIQAVTATAT-GVRYQQSWLCVLCNVKSLQRRCVCITRLERPQNWGVNCCEVRFVILILAPPRTKSTKTAIELGRTFATLFSDISFRQKLLETKTQDDFKQELVHQMQLLSSAEHKASIEEETGPHINKPLKVKEFLQ----------AGRGIYEDLSRRLPYYVSDFTDGMYGSNRSLLKYTTTAIFLYIAILLPAIAFGSLNDESTRGEIDVQKTIVGQSIGGVIYSLLAGSPMVIPITTAPLAIFISVIRGICDDYDLDFPAFYACIGLWNSLFLILGGLFNISLFMKLFKRSTEEVIALFISIAFVGDAVKGTIKIFHKYYHGPTL-VNSSAVEIHHLADMIQH--------PDSSSSSTAPSLSAVLTLCTRERPILCLLLMLGTLWLGYVLFLIKRSPFLHAKVREVVSDCALPISVVIFSFVGSYLFIDIELPVFNYYNGSI-FNIAPLDMLSGMNVLSACGLGFLLALLIFIDQNIVISLTNAPENRLLKGTAYHWDLMLSGFINILMSVLGLPWMHAAFPHSTLHVRQLAKVEQRVEQGH-LYETIVSVKETRLTSLAANVLIGLSVFLLPVPLQWIPKPVLYGLFLYIALTSIDGNQMCDRIALLLKEQTSYPPTHYIRRVPQRKVHYFTGLQLIQLIILCAFGMYPLPYMKMIFPLLMIFLIPVRNSMLPKIIEAKYLDIID 788
BLAST of slc4a-8 vs. Ensembl Cavefish
Match: ENSAMXT00000047690.1 (pep primary_assembly:Astyanax_mexicanus-2.0:APWO02000151.1:229977:263825:-1 gene:ENSAMXG00000011585.2 transcript:ENSAMXT00000047690.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 541.962 bits (1395), Expect = 6.261e-180 Identity = 315/762 (41.34%), Postives = 469/762 (61.55%), Query Frame = 2
Query: 560 MKDFSAEVRATLDIQKFLKEAVLLLDMSGSCLEEIIDSMLLTILANEVTDAKVSLEALVEEAKKTLFIQSSYLTYTYQRLAKTIRGLSLSETEGLMTDQSWLCTMCSLNCIHKRHVAIARLNNPVNMGRSSEGIYFIILVVTPTKEKGTKSDIELGRTFATIFADVEFRQQLLFSESVEQFKELLQY---------HSGDLMEDQAMNRRKSLKVQEVMNQAFHFDKKYLVGSGIVSDFKKRFPVYLMDFRDGFRGKG-TIRKVISATIFLYFACLLPSIAFGVLNYNNTEGKIDVRRVIISQAIGGLCFGFFSGQXXXXXXXXXXXXXFVKIISSICNDYDLDFFAMYSCVGLINSLLLILYAMFDISKLMRWSTRSSEEIFALFVAISFVVDAVKDIYKEFSTHYFSCYLSANNQSTEHLRLSRFKRAFSGIISNIXXXXXXXXXXXXXXXXXXCQREVSILYLFLVAGTVWLAIQLFTSTKTPFLNNAKREMLTDFALPLAVVIMSLIGTYLFKEIEMQPFVIVEEKVKFEASGILKLPWLAIAGAIALAFPLSLLMFMDQNISSAMVNSPANKLKKGSSYHWDLLVVALINAGLSVFGLPLVHGALPHSPLHVKALADLEERIDTAHHVHQTIVKVRETRITSILSHVFIGISLQMLPIPLIYIPVAVLDGLFVYMAVTTLYGNQFFERILLLFTEQSAYPPSHYLRRVPQRKLHIFTGLQIFQLAGLCLLGFSPSPYLKMGFPLLLLFHMVFRHQVV 2815
+ +F EVRA D+ FL +A +LLD + + L+E++ ML + D + S + E LF + + L +TI+ ++ + T G+ QSWLC +C++ + +R V I RL P N G + + F+IL++ P + K TK+ IELGRTFAT+F+D+ FRQ+LL +++ + FK+ L + H + E+ + K LKV+E + G GI D +R P Y+ DF DG G ++ K + IFLY A LLP+IAFG LN +T G+IDV++ I+ Q+IGG+ + +G P++I +TTAPLA+F+ +I IC+DYDLDF A Y+C+GL NSL LIL +F+IS M+ RS+EE+ ALF++I+FV DAVK K F +Y L N+ + E L+ + S + + S C RE IL L L+ GT+WL LF ++PFL+ RE+++D ALP++VVI S +G+YLF +IE+ F + F + + L + + A L F L+LL+F+DQNI ++ N+P N+L KG++YHWDL++ IN +SV GLP +H A PHS LHV+ LA +E+R++ H +++TIV V+ETR+TS+ ++V IG+S+ +LP+PL +IP VL GLF+Y+A+T++ GNQ +RI LL EQ++YPP+HY+RRVPQRK+H FTGLQ+ QL LC G P PY+KM FPLL++F + R+ V
Sbjct: 42 LMNFQEEVRAHRDLNSFLAQASILLDETAASLDEVLRRMLQHV----ARDGQGSCDQ--REVISALFTDAGGQEASVHLLTETIQAVTATAT-GVRYQQSWLCVLCNVKSLQRRCVCITRLERPQNWGVNCCEVRFVILILAPPRTKSTKTAIELGRTFATLFSDISFRQKLLETKTQDDFKQELVHQMQLLSSAEHKASIEEETGPHINKPLKVKEFLQ----------AGRGIYEDLSRRLPYYVSDFTDGMYGSNRSLLKYTTTAIFLYIAILLPAIAFGSLNDESTRGEIDVQKTIVGQSIGGVIYSLLAGSPMVIPITTAPLAIFISVIRGICDDYDLDFPAFYACIGLWNSLFLILGGLFNISLFMKLFKRSTEEVIALFISIAFVGDAVKGTIKIFHKYYHGPTL-VNSSAVEIHHLADMIQH--------PDSSSSSTAPSLSAVLTLCTRERPILCLLLMLGTLWLGYVLFLIKRSPFLHAKVREVVSDCALPISVVIFSFVGSYLFIDIELPVFNYYNGSI-FNIAPLDMLSGMNVLSACGLGFLLALLIFIDQNIVISLTNAPENRLLKGTAYHWDLMLSGFINILMSVLGLPWMHAAFPHSTLHVRQLAKVEQRVEQGH-LYETIVSVKETRLTSLAANVLIGLSVFLLPVPLQWIPKPVLYGLFLYIALTSIDGNQMCDRIALLLKEQTSYPPTHYIRRVPQRKVHYFTGLQLIQLIILCAFGMYPLPYMKMIFPLLMIFLIPVRYGTV 775
BLAST of slc4a-8 vs. Ensembl Cavefish
Match: slc4a11 (solute carrier family 4 member 11 [Source:ZFIN;Acc:ZDB-GENE-090313-183]) HSP 1 Score: 519.235 bits (1336), Expect = 4.187e-171 Identity = 318/799 (39.80%), Postives = 492/799 (61.58%), Query Frame = 2
Query: 509 EDDSVPCLFLSRLEK-IPMKDFSAEVRATLDIQKFLKEAVLLLDMSGSCLEEIIDSMLLTILANEVTDAKVSLEALVEEAKKTLFIQSSYLTYTYQRLAKTIRGLSLSETEGLMTDQSWLCTMCSLNCIHKRHVAIARLNNPVNMGRSSEGIYFIILVVTPTKEKGTKSDIELGRTFATIFADVEFRQQLLFSESVEQFKELL---QYHSGDLMEDQAMNRRKSLKVQEVMNQAFHFDKK----YLVGSGIVSDFKKRFPVYLMDFRDGFRGKG-TIRKVISATIFLYFACLLPSIAFGVLNYNNTEGK-------IDVRRVIISQAIGGLCFGFFSGQXXXXXXXXXXXXXFVKIISSICNDYDLDFFAMYSCVGLINSLLLILYAMFDISKLM-RWSTRSSEEIFALFVAISFVVDAVKDIYKEFSTHYFSCYLSANNQSTEHLRLSRFKRAFSGIISNIXXXXXXXXXXXXXXXXXXCQREVSILYLFLVAGTVWLAIQLFTSTKTPFLNNAKREMLTDFALPLAVVIMSLIGTYLFKEIEMQPFVIVEEKVKFEASGILKLPWLAIAGAIALAFPLSLLMFMDQNISSAMVNSPANKLKKGSSYHWDLLVVALINAGLSVFGLPLVHGALPHSPLHVKALADLEERIDTAHHVHQTIVKVRETRITSILSHVFIGISLQMLPIPLIYIPVAVLDGLFVYMAVTTLYGNQFFERILLLFTEQSAYPPSHYLRRVPQRKLHIFTGLQIFQLAGLCLLGFSPSPYLKMGFPLLLLFHMVFRHQVVPRVIDEKYLNALD 2854
+ D C+ L+ + + + +F E+RA D+ FL+ A +LL + L++++ +ML I + T EE +LF + L++T++ ++ + T G+ QSWLC +C++ + +RHV I+RL+ P N G + + ++IL++ P K K TK+ +ELGRTFA++F+D+ FRQ+LL S++ E+FKE L +YH A R+ + +E + H K + VG GI D +R P Y DF DG G + K ++ +IFLY A LLP+IAFG LN +T G+ DV++ II Q+IGG+ + +G PL+I LTTAP+A+F+ +I IC+DY+LDF A Y+C+GL NSL LI+ +F++S L+ + RS EE+ ALF++I+FV DA+K K F +Y + L AN E R+SR +G + S C R +L L L+ GT+W+ L+ ++PFL+ RE+L+D ALP++V+I S +G+Y+F +I + F + V F + + KL ++ A+ L F L+LL+F+DQNI ++ N+P N+L KG++YHWDL + LIN +SV GLP +H A PHS LHV+ LA +EER++ H +++TIV V+ETR+TS+++++ IG+S+ +LP+PL +IP VL GLF+Y+A+T++ GNQ +R+ LL EQ++YPP+HY+R+VPQRK+H FT LQ+ QL LC G P PY+KM FPLL+ + R+ ++PR+ID KYL+ +D
Sbjct: 11 DSDVHGCVLLNTSRRYVKLMNFEEEIRAHRDLDGFLERASILLHEDEASLDDVLKTMLRHISQDPHTAEP---GCNFEEIMSSLFTDAGSQEVNVHLLSETLQCVTATAT-GIQYQQSWLCILCNVKNLQRRHVCISRLDRPQNWGENCAEVRYVILILAPLKMKSTKTAMELGRTFASMFSDISFRQKLLESKTQEEFKEALVIQRYHL------TATKRKTTTVEEEETDPHSHKPLKCRDFFRVGRGIYEDLCRRLPFYPSDFTDGIVGNNKALVKYMTTSIFLYIAVLLPAIAFGSLNDESTRGENSICVSVSDVQKTIIGQSIGGIIYSLCAGSPLVIPLTTAPIAIFISVIRGICDDYELDFAAFYACIGLWNSLFLIIGGVFNLSLLLVKLFKRSIEEVIALFISIAFVADAMKGTVKIFHKYYHAPTL-ANGSIEELNRISR-DMNLTGELPE---------------SFILCTRARPLLCLLLMLGTLWVGYTLYQFKRSPFLHAKMREILSDCALPISVLIFSYVGSYVFNDIGLPVFDFHKGPV-FRVAPLEKLTGASVLSAMGLGFLLALLIFIDQNIVVSLTNAPENRLLKGTAYHWDLTLSGLINILMSVLGLPWMHAAFPHSTLHVRQLAIVEERVEGGH-LYETIVSVKETRVTSLVANILIGVSVFLLPVPLQWIPKPVLYGLFLYIALTSIDGNQMCDRMALLLKEQTSYPPTHYIRKVPQRKIHYFTFLQMVQLLFLCTFGMYPLPYMKMIFPLLMFILIPIRNCLLPRIIDAKYLDIMD 780
BLAST of slc4a-8 vs. Ensembl Cavefish
Match: slc4a2b (anion exchange protein 2-like [Source:NCBI gene;Acc:103041005]) HSP 1 Score: 196.438 bits (498), Expect = 5.635e-51 Identity = 155/555 (27.93%), Postives = 276/555 (49.73%), Query Frame = 2
Query: 1232 GIVSDFKKRFPVYLMDFRDGFRGKGTIRKVISATIFLYFACLLPSIAFGVLNYNNTEGKIDVRRVIISQAIGGLCFGFFSGQXXXXXXXXXXXXXFVKIISSICNDYDLDFFAMYSCVGLINSLLLILYAMFDISKLMRWSTRSSEEIFALFVAISFVVDAVKDIYKEFSTHYFSCYLSANNQSTEHLRLSRFKRAFSGIISNIXXXXXXXXXXXXXXXXXXCQREVSILYLFLVAGTVWLAIQLFTSTKTPFLNNAKREMLTDFALPLAVVIMSLIGTYLFKEIEMQPFVIVEEKVKFEASGILKLPWLAIAGAIALAFPLSL-------------LMFMDQNISSAMVNSPANKLKKGSSYHWDLLVVALINAGLSVFGLPLVHGALPHSPLHVKALADLEERIDTAHHVHQTIVKVRETRITSILSHVFIGISLQMLPIPLIYIPVAVLDGLFVYMAVTTLYGNQFFERILLLFTEQSAYPPSHYLRRVPQRKLHIFTGLQIFQLAGL-CLLGFSPSPYLKMGFPLLLLFHMVFRHQVVPRVIDEKYLNALD 2854
G++ D ++R+P YL DF+D + ++A IF+YFA L P+I FG L TEG I V +I++ I G+ F QPL+++ + PL +F + S C L++ +G +++++ F+ S L+R+ +R ++EIF+ +++ F+ + + K F H Q + +S + + N + S TN +S++ + ++L L L++GT ++A L + F R ++ DF +P+A++IM L+ Y +E Q + F + K W+ + FP+ + L+FM+ I++ +V+ L KGS +H DLLV+ + ++FGLP + A S HV AL + + + A I +V+E R+T +L + +G+S+ + + L IP+AVL G+F+YM V +L G Q ER+ LL +P Y+R+V ++H+FT LQ+ LA L ++ S S + FP +L+ + + ++PR+ + + LD
Sbjct: 629 GMIRDIRRRYPKYLSDFKDALNPQ-----CMAAVIFIYFAALSPAITFGGLLGEKTEGLIGVSELIVATCIQGVVFCLLGAQPLLVVGFSGPLLVFEEAFYSFCKSNGLEYLTGRVWIGFWLIIIVVVMVAFEGSFLVRFVSRFTQEIFSFLISLIFIYETFSKLAKIFQQHPL--------QRCSFVNVSVLNESEISPMENFTWSSEATNSSSTIVIKG--EPNTALLSLVLMSGTFFIAFYLRKFKNSAFFPGRLRRVIGDFGVPIAILIMVLVD-YSIQETYTQKLSV---PSGFSVTSPDKRGWIVNPLGSEVQFPVWMMAASVLPALLVFILIFMETQITTLIVSKKERMLIKGSGFHLDLLVIVAMGGICALFGLPWMAAATVRSVTHVNALTVMSKAV--APGDKPRIQEVKEQRVTGLLVAILVGLSIVIGDL-LRQIPIAVLFGIFLYMGVMSLNGIQLTERMQLLLMPPKYHPDHTYVRKVRTLRMHLFTALQVVCLAALWAVMSTSAS----LAFPFVLILTVPLKMFLLPRIFSTREMQCLD 1157
BLAST of slc4a-8 vs. Ensembl Cavefish
Match: slc4a2b (anion exchange protein 2-like [Source:NCBI gene;Acc:103041005]) HSP 1 Score: 195.282 bits (495), Expect = 1.298e-50 Identity = 160/584 (27.40%), Postives = 282/584 (48.29%), Query Frame = 2
Query: 1163 KSLKVQEVMNQAFHFDKKYLVGSG-----IVSDFKKRFPVYLMDFRDGFRGKGTIRKVISATIFLYFACLLPSIAFGVLNYNNTEGKIDVRRVIISQAIGGLCFGFFSGQXXXXXXXXXXXXXFVKIISSICNDYDLDFFAMYSCVGLINSLLLILYAMFDISKLMRWSTRSSEEIFALFVAISFVVDAVKDIYKEFSTHYFSCYLSANNQSTEHLRLSRFKR-AFSGIISNIXXXXXXXXXXXXXXXXXXCQREVSILYLFLVAGTVWLAIQLFTSTKTPFLNNAKREMLTDFALPLAVVIMSLIGTYLFKEIEMQPFVIVEEKVKFEASGILKLPWLAIAGAIALAFPLSL-------------LMFMDQNISSAMVNSPANKLKKGSSYHWDLLVVALINAGLSVFGLPLVHGALPHSPLHVKALADLEERIDTAHHVHQTIVKVRETRITSILSHVFIGISLQMLPIPLIYIPVAVLDGLFVYMAVTTLYGNQFFERILLLFTEQSAYPPSHYLRRVPQRKLHIFTGLQIFQLAGL-CLLGFSPSPYLKMGFPLLLLFHMVFRHQVVPRVIDEKYLNALD 2854
KSL+ +E + F + L +G ++ D ++R+P YL DF+D + ++A IF+YFA L P+I FG L TEG I V +I++ I G+ F QPL+++ + PL +F + S C L++ +G +++++ F+ S L+R+ +R ++EIF+ +++ F+ + + K F H N +S + +S +N SS + ++L L L++GT ++A L + F R ++ DF +P+A++IM L+ Y +E Q + F + K W+ + FP+ + L+FM+ I++ +V+ L KGS +H DLLV+ + ++FGLP + A S HV AL + + + A I +V+E R+T +L + +G+S+ + + L IP+AVL G+F+YM V +L G Q ER+ LL +P Y+R+V ++H+FT LQ+ LA L ++ S S + FP +L+ + + ++PR+ + + LD
Sbjct: 609 KSLEEKEALLTPFKPEDDPLQRTGRPFGGMIRDIRRRYPKYLSDFKDALNPQ-----CMAAVIFIYFAALSPAITFGGLLGEKTEGLIGVSELIVATCIQGVVFCLLGAQPLLVVGFSGPLLVFEEAFYSFCKSNGLEYLTGRVWIGFWLIIIVVVMVAFEGSFLVRFVSRFTQEIFSFLISLIFIYETFSKLAKIFQQHPLQRCSFVNVSVLNESEISPMENFTWSSEATN-----------SSSTIVIKGEPNTALLSLVLMSGTFFIAFYLRKFKNSAFFPGRLRRVIGDFGVPIAILIMVLVD-YSIQETYTQKLSV---PSGFSVTSPDKRGWIVNPLGSEVQFPVWMMAASVLPALLVFILIFMETQITTLIVSKKERMLIKGSGFHLDLLVIVAMGGICALFGLPWMAAATVRSVTHVNALTVMSKAV--APGDKPRIQEVKEQRVTGLLVAILVGLSIVIGDL-LRQIPIAVLFGIFLYMGVMSLNGIQLTERMQLLLMPPKYHPDHTYVRKVRTLRMHLFTALQVVCLAALWAVMSTSAS----LAFPFVLILTVPLKMFLLPRIFSTREMQCLD 1165
BLAST of slc4a-8 vs. Ensembl Sea Lamprey
Match: slc4a11 (solute carrier family 4 member 11 [Source:ZFIN;Acc:ZDB-GENE-090313-183]) HSP 1 Score: 570.852 bits (1470), Expect = 0.000e+0 Identity = 337/787 (42.82%), Postives = 490/787 (62.26%), Query Frame = 2
Query: 548 EKIPMKDFSAEVRATLDIQKFLKEAVLLLDMSGSCLEEIIDSMLLTILAN----EVTDAKVSLEALVEEAKKTLFIQSSYLTYTYQRLAKTIRGLSLSETEGLMTDQSWLCTMCSLNCIHKRHVAIARLNNPVNMGRSSEGIYFIILVVTPTKEKGTKSDIELGRTFATIFADVEFRQQLLFSESVEQFKELLQYHSGDLM---EDQAMNRRKSLKVQEVMNQAFHFDKKYLVGSGIVSDFKKRFPVYLMDFRDGFRGKGTIRKVISATIFLYFACLLPSIAFGVLNYNNTEGKIDVRRVIISQAIGGLCFGFFSGQXXXXXXXXXXXXXFVKIISSICNDYDLDFFAMYSCVGLINSLLLILYAMFDISKLMRWSTRSSEEIFALFVAISFVVDAVKDIYKEFSTHYF-----SCYLSANNQSTEHLRLSRFKRAFSGIISNIXXXXXXXXXXXXXXXXXXCQREVSILYLFLVAGTVWLAIQLFTSTKTPFLNNAKREMLTDFALPLAVVIMSLIGTYLFKEIEMQ----PFVIVEEKVKFEASGILKLPWLAIAGAIALAFPLSLLMFMDQNISSAMVNSPANKLKKGSSYHWDLLVVALINAGLSVFGLPLVHGALPHSPLHVKALADLEERIDTAHHVHQTIVKVRETRITSILSHVFIGISLQMLPIPLI-YIPVAVLDGLFVYMAVTTLYGNQFFERILLLFTEQSAYPPSHYLRRVPQRKLHIFTGLQIFQLAGLCLLGFSPSPYLKMGFPLLLLFHMVFRHQVVPRVIDEKYLNALDK 2857
+ + +K+FS EVRA D+ +FL +A +LLD+ LE + ML ++L + E +A+ SL KT I +L L++TI+ ++++ + GL QSWLC +C+ + R V IARL N G + + F+ILV+ P K K TK+ E+GRTFATIF D+ FRQQL+ + S E+FK L DL E+Q + + S+ +Q Q F L+G I D ++R P Y DF DG I K I A IFLYFACLLPSIAFG LN NT G IDV++ +++Q++GG+ F SGQPLI+LLTTAPLAL++ I +IC++++LDF A Y+C+GL NS L LYA+ +S + S RS EEIFALF++I+FVVDA+KDI K F +Y C + NN S + +G+ S R+V++L L L+ GTVWL L+ K P+L+ RE+L+D A+PL+V+ S +G+Y+F++I+ F + F + + L +I A+ + F LS+L FM+ +++++ N+P N+LKKG+SYHWDLL+VA++NA S+FGLP +H A PHSPLHV+ALA +EER++ H V +T +TR+ +L+H+ +G+SL L + +IP VLDG+F+Y+A+T+L GNQ F+R+ LLFTEQ+AYPP+HY+RRVPQRK+H FTGLQ+ QLA LC +GFSP PY+KM FP+++L + R VP++I+ +YL+ +D+
Sbjct: 1 QSVKIKNFSEEVRAGRDVDRFLSQAAVLLDLPSRSLESTLCHMLESVLEDNPCAEPREARCSL-------LKTDCINKVHL------LSETIQAVTVNPS-GLHYQQSWLCVLCTETTLQHREVCIARLERAQNWGENCCEVRFVILVLAPPKSKSTKTATEVGRTFATIFVDIGFRQQLIEARSPEEFKHALLLRRHDLTAQHEEQEDSSKSSVSIQHPHEQVFGAVVWPLMG--IWEDIRRRLPYYSSDFTDGILRNRCIGKYIIAMIFLYFACLLPSIAFGSLNDINTRGAIDVQKTLVAQSMGGVLFAVLSGQPLIVLLTTAPLALYIYAIRTICDEFELDFHAYYACIGLWNSFFLTLYALLHMSTRLHLSKRSIEEIFALFISIAFVVDAIKDIIKIFKQNYLPGEPGGCGSAGNNTSDDGWE------GAAGVDSG----------------GPKGSRDVALLALLLMLGTVWLGSTLYQFRKRPYLHLQAREILSDCAMPLSVIAFSFLGSYVFRDIDRMVTGLKFSYTPSESYFALAPLNLLTVGSICSAMGIGFLLSILFFMEHTMAASLTNAPHNRLKKGTSYHWDLLLVAVLNATFSLFGLPWMHAAFPHSPLHVRALATVEERVEDGH-VDETQGNSLKTRVPVLLAHMLLGLSLFFLLPLPLQWIPRPVLDGIFLYIALTSLDGNQLFQRLALLFTEQTAYPPTHYVRRVPQRKIHYFTGLQLLQLAVLCGVGFSPIPYMKMVFPVIMLAALPVRFFAVPKIIESRYLDVMDE 748
BLAST of slc4a-8 vs. Ensembl Sea Lamprey
Match: SLC4A2 (solute carrier family 4 member 2 [Source:HGNC Symbol;Acc:HGNC:11028]) HSP 1 Score: 207.608 bits (527), Expect = 1.961e-55 Identity = 161/556 (28.96%), Postives = 282/556 (50.72%), Query Frame = 2
Query: 1229 SGIVSDFKKRFPVYLMDFRDGFRGKGTIRKVISATIFLYFACLLPSIAFGVLNYNNTEGKIDVRRVIISQAIGGLCFGFFSGQXXXXXXXXXXXXXFVKIISSICNDYDLDFFAMYSCVGLINSLLLILYAMFDISKLMRWSTRSSEEIFALFVAISFVVDAVKDIYKEFSTH-YFSCYLSANNQSTEHLRLSRFKRAFSGIISNIXXXXXXXXXXXXXXXXXXCQREVSILYLFLVAGTVWLAIQLFTSTKTPFLNNAKREMLTDFALPLAVVIMSLI-----GTYLFKEIEMQPFVIVEEKVK------FEASGILKLPWLAIAGAIA--LAFPLSLLMFMDQNISSAMVNSPANKLKKGSSYHWDLLVVALINAGLSVFGLPLVHGALPHSPLHVKALADLEERIDTAHHVHQTIVKVRETRITSILSHVFIGISLQMLPIPLIYIPVAVLDGLFVYMAVTTLYGNQFFERILLLFTEQSAYPPSHYLRRVPQRKLHIFTGLQIFQLAGLCLLGFSPSPYLKMGFPLLLLFHMVFRHQVVPRVIDEKYLNALD 2854
G+V D ++R+P YL D RD + ++A IF+YFA L P+I FG L T+G + V +IIS + G+ F QPL+I+ + PL +F + S C+ +++ +G L+++L F+ S ++R+ +R ++EIF++ +++ F+ + +YK F H S Y +N +T + S I++ + + + Q ++L L L++GT ++A L + FL R ++ DF +P+A+++M L+ TY K F + + A G + WL A I L F +L+FM+ I++ +V+ L KGS +H DLL++ ++ A ++FGLP + A S HV AL + + TA I V+E RIT +L + +G+S+ + + L IP+AVL G+F+YM VT+L G QF++R++L+F +P + Y +V +++++TG+Q L GL + S + FP +L+ + R ++ R+ ++ L LD
Sbjct: 467 GGLVRDARRRYPHYLSDLRDALNPQ-----CLAAVIFIYFAALSPAITFGGLLSEKTQGLMGVSELIISTCLQGILFALLGAQPLLIIGFSGPLLVFEEAFFSFCSSQGVEYLTGRVWIGFWMVLIVLLLVAFEGSFMVRFISRFTQEIFSILISLIFIYETFSKLYKVFQDHPLLSTYPVISNMTTNS------DTSNSSIVNGTTAATPKVLN----------QPNTALLSLLLMSGTFFIAFFLRKFKNSRFLAGKVRRVIGDFGVPIAILVMVLVDFGVPNTYTQKLNVPDGFSVTSPSKRGWVINPLGAEGTFPV-WLMFACVIPGLLVF---ILIFMESQITTLIVSKKERMLLKGSGFHLDLLLIVVMGAICTIFGLPWLTAATVRSVTHVNALTVMSKA--TAPGDKPRIECVKEQRITGLLVAIIVGLSMVLGQV-LRQIPLAVLFGIFLYMGVTSLNGIQFYDRLMLVFMPAKYHPDTAYATKVRTLRMNLYTGIQFVCLGGLWAVM---STAASLAFPFVLILTVPLRRFLLSRIFTDRELKCLD 991
BLAST of slc4a-8 vs. Ensembl Sea Lamprey
Match: slc4a7 (solute carrier family 4 member 7 [Source:ZFIN;Acc:ZDB-GENE-140106-104]) HSP 1 Score: 198.364 bits (503), Expect = 2.324e-52 Identity = 169/566 (29.86%), Postives = 278/566 (49.12%), Query Frame = 2
Query: 1229 SGIVSDFKKRFPVYLMDFRDGFRGKGTIRKVISATIFLYFACLLPSIAFGVLNYNNTEGKIDVRRVIISQAIGGLCFGFFSGQXXXXXXXXXXXXXFVKIISSICNDYDLDFFAMYSCVGLINSLLLILYAMFDISKLMRWSTRSSEEIFALFVAISFVVDAVKDIY-------------KEFSTHYFSCYLSANNQSTEHLR-LSRFKRAFSGIISNIXXXXXXXXXXXXXXXXXXCQR------EVSILYLFLVAGTVWLAIQLFTSTKTPFLNNAKREMLTDFALPLAVVIMSLIGTYL-FKEIEMQ---PFVIVEEKVKFEASGILKLPWLAIAGAIALAFPLSLLMFMDQNISSAMVNSPANKLKKGSSYHWDLLVVALINAGLSVFGLPLVHGALPHSPLHVKALADLEERIDTAHHVHQTIVKVRETRITSILSHVFIGISLQMLPIPLIYIPVAVLDGLFVYMAVTTLYGNQFFERILLLFTEQSAYPPSHYLRRVPQRKLHIFTGLQIFQLAGLCLLGFSPSPYLKMGFPLLLLFHMVFRHQVVPRVIDEKYLNALD 2854
G+V D K++ P Y D+RD + I++ +FLY AC+ P I FG L TEG+I + ++ G+ + F+GQPL IL +T P+ +F KI+ C DY+L + ++ +C+GL + L +L D S L+ + TR +EE FA + I F+ +A++ + E T Y + + S E L S R+ I ++++++ + +C +V + L T +L+ L + R ++DFA+ L ++ M +I +L ++Q F + + I PW I A A ++L+FMDQ I++ ++N +KLKKG YH DLL VA++ A S+ GLP A S HV +L E +A + +RE R+T ++ V +G S+ M + L +IP+ VL G+F+YM ++L G QFF+RI L P YLR VP RK+H+FT +Q L L ++ SP+ + FP+++L +VF +++ ++ L+ LD
Sbjct: 487 GGLVRDIKRKIPFYWSDYRDSLN-----LQCIASFLFLYCACMSPVITFGGLLGEATEGRISAIESLFGASMTGIAYSLFAGQPLTILGSTGPVLVFEKILYKFCKDYNLSYLSLRACIGLWTAFLCLLLVATDASSLVCYITRFTEEAFASLICIIFIYEALEKLVHLGETYEVNMHADPELLTQYSCVCVEPSVPSNETLDAWSNMNRSADSIPWG-NLTVSKCLELHGQFVGTACGHHGPYIPDVLFWSIILFFATFFLSGFLKQFKTMRYFPTKVRSTVSDFAVFLTILSMVVIDYFLGIPSPKLQVPSEFKPTRDDRGWIVDPIGPNPWWTILAAAIPALLCTILVFMDQQITAVIINRKEHKLKKGCGYHLDLLWVAIMLAVCSIMGLPWFVAATVLSISHVNSLKVESEC--SAPGEQPKFLGIREQRVTGLMIFVLMGCSVFMTGV-LKFIPMPVLYGVFLYMGASSLKGIQFFDRIKLFVMPAKHQPDFIYLRHVPLRKVHLFTAVQFTCLVLLWVIKASPAAIV---FPMMVL-ALVFIRKLLDFCFTKRELSWLD 1039
BLAST of slc4a-8 vs. Ensembl Sea Lamprey
Match: SLC4A2 (solute carrier family 4 member 2 [Source:HGNC Symbol;Acc:HGNC:11028]) HSP 1 Score: 184.496 bits (467), Expect = 8.529e-48 Identity = 159/559 (28.44%), Postives = 274/559 (49.02%), Query Frame = 2
Query: 1229 SGIVSDFKKRFPVYLMDFRDGFRGKGTIRKVISATIFLYFACLLPSIAFGVLNYNNTEGKIDVRRVIISQAIGGLCFGFFSGQXXXXXXXXXXXXXFVKIISSICNDYDLDFFAMYSCVGLINSLLLILYAMFDISKLMRWSTRSSEEIFALFVAISFVVDAVKDIYKEFSTHYFSCYLSANNQSTEHLRLSRFKRAFSGIISN----IXXXXXXXXXXXXXXXXXXCQREVSILYLFLVAGTVWLAIQLFTSTKTPFLNNAKREMLTDFALPLAVVIMSLIGTYLFKEIEMQPFVIVEEKVKFEASGILKLPWLAIAGAIALAFPLSL-------------LMFMDQNISSAMVNSPANKLKKGSSYHWDLLVVALINAGLSVFGLPLVHGALPHSPLHVKALADLEERIDTAHHVHQTIVKVRETRITSILSHVFIGISLQMLPIPLIYIPVAVLDGLFVYMAVTTLYGNQFFERILLLFTEQSAYPPSHYLRRVPQRKLHIFTGLQIFQLAGLCLLGFSPSPYLKMGFPLLLLFHMVFRHQVVPRVIDEKYLNALD 2854
G+V D ++R+P Y D +D + ++A IF+YFA L P+I FG L T+G I V +IIS +I + F S QPL+I+ + PL +F + S C D+++ +G L+++L F+ S L+R+ +R ++EIF++ ++I F+ + ++K F H + A SG+ N I + ++ + Q S+L L L++GT ++A L + FL R ++ DF +P+A++IM L+ + + + Q + + F + + WL + FP+ + L+FM+ I++ +V+ +L KGS +H DLL++ L+ ++ G+P + A S HV AL + + TA I V+E R T +L V IG+S+ + + L IP+AVL G+F+YM VT++ G Q ++R+LL F +P S Y +V +++++T +Q LA LL S + FP +L+ + RH ++PR+ L LD
Sbjct: 679 GGVVRDARRRYPFYPSDIKDAVDPQ-----CLAAVIFIYFAALSPAITFGGLLGEKTQGLIGVSELIISTSIQSIFFALLSAQPLLIVGFSGPLLVFEEAFFSFCWSQDVEYLTGRLWIGFWLILIVLLTVAFEGSFLVRYISRFTQEIFSILISIIFIYETFYKLFKVFKEHPLLKTYTIGGTDL----------AGSGVWGNASMVIGSATAAARNDTDAPTKMPSQPNTSLLSLVLMSGTFFIAFFLRKLKNSRFLAGKVRRVIGDFGVPIAILIMVLVDSAI-PDTYTQKLAVPD---GFSVTSPDQRSWLVNPLGVRSTFPVWMMFACVVPAALVFILIFMETQITTLIVSKSERRLVKGSGFHLDLLLIVLMGGASALLGVPWLTAATVRSVTHVNALTVMSKA--TAPGEKPRIECVKEQRATGLLVAVLIGLSVVLGEV-LRRIPLAVLFGIFLYMGVTSVNGIQMYDRLLLAFMPAKHHPDSAYASKVKTWRMNMYTAIQFVCLA---LLWVVMSTAASLAFPFVLILTVPLRHFLLPRIFTAHELRCLD 1212
BLAST of slc4a-8 vs. Ensembl Sea Lamprey
Match: SLC4A4 (solute carrier family 4 member 4 [Source:HGNC Symbol;Acc:HGNC:11030]) HSP 1 Score: 133.65 bits (335), Expect = 1.911e-33 Identity = 120/444 (27.03%), Postives = 214/444 (48.20%), Query Frame = 2
Query: 1229 SGIVSDFKKRFPVYLMDFRDGFRGKGTIRKVISATIFLYFACLLPSIAFGVLNYNNTEGKIDVRRVIISQAIGGLCFGFFSGQXXXXXXXXXXXXXFVKIISSICNDYDLDFFAMYSCVGLINSLLLILYAMFDISKLMRWSTRSSEEIFALFVAISFVVDAVKDI-----YKEFSTHYFSCYLSANNQSTEHLRLSRFKRAFSGIISNIXXXXXXXXXXXXXXXXXXCQ--REVSILYLFLVAGTVWLAIQLFTSTKTPFLNNAKREMLTDFALPLAVVIMSLIGTYLFKEIEMQPFVIVEE-KVKFEASGILKLP------WLAIAGAIALAFPLSLLMFMDQNISSAMVNSPANKLKKGSSYHWDLLVVALINAGLSVFGLPLVHGALPHSPLHVKALADLEERIDTAHHVHQTIVKVRETRITSILSHVFIGISLQMLPI 2518
G+ D K++ P + D D + +SAT+F+Y A + +I FG L + T+ V + A+ G F F+GQPLIIL +T P+ +F +++ + + D D+ +GL ++ + ++ D S L+++ TR +EE F+ ++ F+ DA+K + Y + Y Y++ + + + K+ + +I+ + + + S +C+ +V+++ L L GT + + L + R++++DF++ L+ I + +G + +E V+ E K G P W+ + A+ A +++L+FMDQ I++ +VN NKLKKGS YH DL VA++ A S GLP A S H+ +L E +A + VRE RIT +L V G+S+ + PI
Sbjct: 4 GGLFKDIKRKLPFFCSDIYDALS-----IQSLSATLFIYLATITNAITFGGLLGDATDNMQGVLESFLGTALSGAVFCLFAGQPLIILSSTGPVLVFERLLFNFSKENDFDYLEFRLWIGLWSAFMSLILVATDASYLVQYFTRFTEEGFSALISFIFIYDAIKKMLGLFNYYPINLDYKPDYITLYSCTCQAPDPEWGKKLNTAVINAALYNKKECSKYGGSLSGKACKFVPDVALVSLLLFMGTYYTTMALKRFKTGRYFPTTIRKLISDFSIILS--IFTFVGLDILIGLETPKLVVPTEFKPTSAKRGWFVPPFGGNPWWVYLVSAVP-AILITILVFMDQQITAIIVNRKENKLKKGSGYHLDLFWVAVLMATCSFLGLPWYVAATVLSIAHIDSLK--METETSAPGEQPKFLGVREQRITGVLVFVLTGVSVFLAPI 437
BLAST of slc4a-8 vs. Ensembl Yeast
Match: BOR1 (Boron efflux transporter of the plasma membrane; binds HCO3-, I-, Br-, NO3- and Cl-; has similarity to the characterized boron efflux transporter A. thaliana BOR1 [Source:SGD;Acc:S000005219]) HSP 1 Score: 89.7373 bits (221), Expect = 6.155e-19 Identity = 71/257 (27.63%), Postives = 118/257 (45.91%), Query Frame = 2
Query: 1985 PFLNNAKREMLTDFALPLAVVIMSLI---GTYL----FKEIEMQPFVIVEEKVKFEASGILKLPWLAIAGA-IALAFP--LSLLMFMDQNISSAMVNSPANKLKKGSSYHWDLLVVALINAGLSVFGLPLVHGALPHSPLHVKALADLEERIDTAHHVHQTIVKVRETRITSILSHVFI-GISLQMLPIPLIYIPVAVLDGLFVYMAVTTLYGNQFFERILLLFTEQSAYPPSHYLRRVPQRKLHIFTGLQIFQLAG 2722
P ++ R ++D++ L+V+ S G YL FK++ + KV + L + + IAL F L++L + D N+SS M KLKK SS+H+D ++ L V G+P +G +P +PLH + L +Q ++ E R T+ + I G + L + L IP AVL GLF M + L N +R++ LF++ + + L +V ++ + IF + AG
Sbjct: 260 PLFSHRIRTFISDYSTALSVLFWSSFTHFGGYLHDVKFKKLPITKAFFPTSKVNRPQNTWLAYEPIPVKDVFIALPFGIFLTILFYFDHNVSSLMAQRHQYKLKKPSSFHYDFALLGLTTCISGVLGIPAPNGLIPQAPLHTETLL--------VRDSNQKVISCVEQRFTNTFQGLMILGTMTRPLLVCLGEIPQAVLSGLFFIMGINGLMTNSIIQRLVFLFSDPNRRDNTSPLMKVSKKSMLIFLSFSLTGFAG 508 HSP 2 Score: 66.6254 bits (161), Expect = 1.172e-11 Identity = 48/173 (27.75%), Postives = 88/173 (50.87%), Query Frame = 2
Query: 1223 VGSGIVSDFKKRFPVYLMDFRDGFRGKGTIRKVISATIFLYFACLLPSIAFGVLNYNNTEGKIDVRRVIISQAIGGLCFGFFSGQXXXXXXXXXXXXXFVKIISSICNDYDLDFFAMYSCVGLINSLLLILYAMFDISKLMRWSTRSSEEIFALFVAISFVVDAVKDIYKEFS 1741
+G GI D K R P Y D+ D F +VI + + YF LLP+IAF ++ T+ V V++S A+ G+ FG GQPL I+ T P+++F + I + +F + + + + ++ A + L+++ T +IF LF+ + ++ ++ + ++FS
Sbjct: 58 LGIGIWLDLKDRIPYYKSDWVDAFN-----YRVIPSIVDTYFNNLLPAIAFAQDMFDRTDNSYGVNEVLLSSAMAGIVFGVLGGQPLCIVGVTGPISIFNYTVYEIIKPLNTSYFGFMFWICMWSMIFHLVLAFTNAVCLLQYVTTFPCDIFGLFINVVYIQKGIQILTRQFS 225
BLAST of slc4a-8 vs. Ensembl Nematostella
Match: EDO40610 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S6T5]) HSP 1 Score: 358.992 bits (920), Expect = 3.046e-116 Identity = 192/327 (58.72%), Postives = 236/327 (72.17%), Query Frame = 2
Query: 1898 CQREVSILYLFLVAGTVWLAIQLFTSTKTPFLNNAKREMLTDFALPLAVVIMSLIGTYLFKEIEMQPFVIVEEKVKFEASGILKLPWL--------AIAGAIALAFPLSLLMFMDQNISSAMVNSPANKLKKGSSYHWDLLVVALINAGLSVFGLPLVHGALPHSPLHVKALADLEERIDTAHHVHQTIVKVRETRITSILSHVFIGISLQMLPIPLIYIPVAVLDGLFVYMAVTTLYGNQFFERILLLFTEQSAYPPSHYLRRVPQRKLHIFTGLQIFQLAGLCLLGFSPSPYLKMGFPLLLLFHMVFRHQVVPRVIDEKYLNALD 2854
C RE LYL L GTV L + L+ K+PFL+ KRE L D+ALP+AV+ S IGTY F E F++SG + L A+ GA L F LSLL FMDQNISSAMVN+P N+LKKGS++H DLLVVA+IN LS FGLP +HGALPHSPLHV+ALAD+EER+D H V IVKVRETR+T++++H+ IG+SL MLP PL YIP AVLDGLF+++AVT+L NQ FER+LL TEQSAYPP+HY+RRVPQRK+H +TG+Q+ QL LC GFSP PYLKM FP+LLL + RH VVPRVI+ K+L+A+D
Sbjct: 4 CSREAGTLYLLLSLGTVLLGVTLYNFKKSPFLDANKREALADYALPVAVLFFSFIGTYFFSG---------ESLHTFKSSGAVTLKPSSLSLLSAGAVFGACGLGFCLSLLFFMDQNISSAMVNNPGNRLKKGSAFHLDLLVVAIINGILSAFGLPWIHGALPHSPLHVRALADVEERVDQGH-VFDIIVKVRETRLTTLIAHILIGLSLLMLPTPLDYIPTAVLDGLFLFVAVTSLDDNQMFERLLLFVTEQSAYPPNHYIRRVPQRKMHAYTGMQMLQLGILCGFGFSPMPYLKMVFPVLLLLLLPIRHLVVPRVIERKFLDAID 320
BLAST of slc4a-8 vs. Ensembl Nematostella
Match: EDO40611 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S6T6]) HSP 1 Score: 245.743 bits (626), Expect = 3.734e-70 Identity = 144/296 (48.65%), Postives = 177/296 (59.80%), Query Frame = 2
Query: 1898 CQREVSILYLFLVAGTVWLAIQLFTSTKTPFLNNAKREMLTDFALPLAVVIMSLIGTYLFKEIEMQPFVIVEEKVKFEASGILKLPWLAIAGAIALAFPLSLLMFMDQNISSAMVNSPANKLKKGSSYHWDLLVVALINAGLSVFGLPLVHGALPHSPLHVKALADLEERIDTAHHVHQTIVKVRETRITSILSHVFIGISLQMLPIPLIYIPVAVLDGLFVYMAVTTLYGNQFFERILL---LFTEQSAYPPSHYLRRVPQRKLHIFTGLQIFQLAGLCLLGFSPSPYLKMGFPL 2776
C RE LYL L GTV L + L+ K+PFL+ KRE L D+ALP+AV+ S IGTY F V+V SS + +LKKGS++H DLLVVA+IN LS FGLP +HGALPHSPLHV+ALAD+EER+D HV IVKVRETR+T++++H+ IG+SL MLP PL YIP AVLDGL + + Q F LL F QSAYPP+HY+RRVPQRK+H +TG+Q+ QL LC GFSP PYLKM FP+
Sbjct: 404 CSREAGTLYLLLSLGTVLLGVTLYNFKKSPFLDANKREALADYALPVAVLFFSFIGTYFFSGESCDIVVVVL-------------------------------------CSSTHIQ----ELKKGSAFHLDLLVVAIINGILSAFGLPWIHGALPHSPLHVRALADVEERVDQG-HVFDIIVKVRETRLTTLIAHILIGLSLLMLPTPLDYIPTAVLDGL------ASSHNAQVFA--LLENNCFLLQSAYPPNHYIRRVPQRKMHAYTGMQMLQLGILCGFGFSPMPYLKMVFPV 649 HSP 2 Score: 232.646 bits (592), Expect = 1.683e-65 Identity = 133/338 (39.35%), Postives = 202/338 (59.76%), Query Frame = 2
Query: 500 DETEDDSVPCLFLSRLEKIPMKDFSAEVRATLDIQKFLKEAVLLLDMSGSCLEEIIDSMLLTILANEVTDAKVSLEALVEEAKKTLFIQSSYLTYTYQRLAKTIRGLSLSETEGLMTDQSWLCTMCSLNCIHKRHVAIARLNNPVNMGRSSEGIYFIILVVTPTKEKGTKSDIELGRTFATIFADVEFRQQLLFSESVEQFKELLQYHSGDLMEDQAMNRRKSLKVQEVMNQA----------FHFDKKYLVGS--GIVSDFKKRFPVYLMDFRDGFRGKGTIRKVISATIFLYFACLLPSIAFGVLNYNNTEGKIDVRRVIISQAIGGLCFGFFSGQ 1477
D+ E ++ L L + +KI MK+FS EVRA DI +FL++ +LL++ + +E+IID ML I+ ++ KV+ A A+ F + S L+ I+G +SE G Q+WL M L I + H+A++RL + N+GR+ +G + ++L+++P K K TK+ +ELGRTFAT+ +D++FRQ LL +ES E+F ++L DL + NR K +++ A F+F + + GI DF +R P YL DF+DG G T+ K++S IFLYFAC+LPS+AFGVLN NT+GK+DV++V++SQ GGL F GQ
Sbjct: 6 DDYEKET--SLMLVKHQKIDMKNFSTEVRARKDIDRFLEKPTVLLNVHKTKIEDIIDLMLDKIIEDKQLQ-KVNFSA----ARTAFFTKDSV-----HCLSHVIQGTEISEGGGWEETQNWLVAMADLPSIQQSHIAMSRLRHATNLGRTLQGTHLVVLILSPVKTKKTKNSLELGRTFATLLSDIDFRQSLLEAESKEEFVKVLAERKSDL----SNNRNKPEINSKLVRSASKGFNPYHCVFNFQETSTMKPCRGIRDDFMRRMPHYLSDFKDGVVGHRTLFKLVSTVIFLYFACILPSVAFGVLNSKNTKGKMDVQKVLVSQVFGGLFFSLLGGQ 327
BLAST of slc4a-8 vs. Ensembl Nematostella
Match: EDO31793 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SWX4]) HSP 1 Score: 191.045 bits (484), Expect = 4.023e-50 Identity = 160/548 (29.20%), Postives = 267/548 (48.72%), Query Frame = 2
Query: 1166 SLKVQEVMNQAFHFD-----KKYLVGSGIVSDFKKRFPVYLMDFRDGFRGKGTIRKVISATIFLYFACLLPSIAFGVLNYNNTEGKIDVRRVIISQAIGGLCFGFFSGQXXXXXXXXXXXXXFVKIISSICNDYDLDFFAMYSCVGLINSLLLILYAMFDISK--LMRWSTRSSEEIFALFVAISFVVDAVKDIYKEFSTHYFSCYLSANNQSTEHLRLSRFKRAFSGIISNIXXXXXXXXXXXXXXXXXXCQREVSILYLF---LVAGTVWLAIQLFTSTKTPFLNNAKREMLTDFALPLAVVIMSLIGTYLFKEIEMQPFVIVEEKVK--FEASGILKLPWL-------------AIAGAIALAFPLSLLMFMDQNISSAMVNSPANKLKKGSSYHWDLLVVALINAGLSVFGLPLVHGALPHSPLHVKALADLEERIDTAHHVHQTIVKVRETRITSILSHVFIGISLQMLPIPLIYIPVAVLDGLFVYMAVTTLYGNQFFERILLLFTEQSAYPPSHYLRRVPQRKLHIFTGLQIFQLAGLCLL 2734
L+ QE + ++ + + L G++ D K+RFP Y D D F + + ATI +Y ACL P+I+FG L Y T+G + V +I+S A+ G+ F F+GQPLII+ T PL LF + ++ +D ++ + VG+ ++LI +A+ + L+R+ TR +EEIFA +++ F+ D +K IY F + + SG N+ ++VS LF L GT ++A + + FLN+ R +++DF + +A+V M L+ E+ Q + V F+ + W AI GA+ A +S+L+FM+ + +++ N+LKKG Y+ DL VV + SV GLP + H+ H+ AL + + A H +++V+E R+T+I+ HV IG+++ + P+ + PV VL G+FV++ ++L QF ER LLF + +P Y+R V K++ FT +Q+ +CLL
Sbjct: 340 DLETQETVTESLELEDDPLKRTGLFCGGLLRDVKRRFPYYKSDMTDSFNWR-----CVMATILVYVACLAPAISFGGLLYKKTKGWMGVAEMIVSTALSGVIFALFAGQPLIIIGATGPLLLFETNVFNLSESFDFEYMPWRAWVGIW--VMLICWALVAMEGCFLIRYFTRFTEEIFACMISLIFIYDGIKYIYDIFGLYPLT----------------------SGTTENVD------------------GKDVSNTALFTTILFFGTFFVAHIIRDVRHSRFLNHTLRRVISDFGVLIAIVAMILV------ELSAQSIYVQRLNVPDGFDVTSPHLRGWYVNPMGTERRLGADAIFGALVPAILVSILVFMEVEFCNVILDKKDNQLKKGPGYNLDLFVVGFLMGMCSVLGLPWMCATPVHTVSHLHAL--MVHSTNHAPGEHPQLLEVKEQRVTNIIIHVLIGLTMLLAPV-IRLTPVVVLFGVFVHLGFSSLSHLQFVERFKLLFVSPNHHPDRRYVRSVSTGKMNAFTLVQV-----VCLL 826
BLAST of slc4a-8 vs. Ensembl Nematostella
Match: EDO45844 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RRK7]) HSP 1 Score: 188.348 bits (477), Expect = 4.079e-49 Identity = 178/681 (26.14%), Postives = 311/681 (45.67%), Query Frame = 2
Query: 878 SLNCIHKRHVAIARLNNPVNMGRSSE---GIYFIILVVTPTKEKGTKSDIELGRTFATIFADVEFRQQLLFSESVEQF--------------------KELLQYHSGDLMEDQAMNRRKSLKVQEVMNQAFHFDKKYLVGSG-----IVSDFKKRFPVYLMDFRDGFRGKGTIRKVISATIFLYFACLLPSIAFGVLNYNNTEGKIDVRRVIISQAIGGLCFGFFSGQXXXXXXXXXXXXXFVKIISSICNDYDLDFFAMYSCVGLINSLLLILYAMFDISKLMRWSTRSSEEIFALFVAISFVVDAVKDIYKEFSTHYFSCYLSANNQSTEHLRLSRFKRAFSGIISNIXXXXXXXXXXXXXXXXXXCQREVSILYLFLVAGTVWLAIQLFTSTKTPFLNNAKREMLTDFALPLAVVIMSLIGTYLFKEIEMQPFVIVEE--KVKFEASGILKLPWLA-------------IAGAIALAFPLSLLMFMDQNISSAMVNSPANKLKKGSSYHWDLLVVALINAGLSVFGLPLVHGALPHSPLHVKALADLEERIDTAHHVHQT--IVKVRETRITSILSHVFIGISLQMLPIPLIYIPVAVLDGLFVYMAVTTLYGNQFFERILLLFTEQSAYPPSHYLRRVPQRKLHIFTGLQIFQLAGLCLLGFSPSPYLKMGFPLLLL 2785
+L+C+ A RL +G +E + F+ +++ P + T E+GR+ AT+ +D F +SES E K+LL + A R+++ ++ + QA + L +G ++ D K R Y+ DF+DGF + + T+FLYFA P++AFG L T+ + V VI + GL F FSGQPLII+ T P+ +F + I C +++F +G ++L L F+ L+R+ TR +EE+FA +++ F+ +A+ +YK F + S N + + I NI + ++L L+ GT ++A + + F R +++DF + +A++ M +I + ++ + P + + + KV F + K W + AI A + +L+FM+ ++ ++N N L+K Y+ DLL++ +I S+FGLP + A S H AL+ T+H + +V+VRE RIT+IL HV G+S+ + P+ L ++PV VL G+ +Y+ +++L Q R++++ +P Y+R+VP K+H G + QLA L +L L FP ++
Sbjct: 249 TLDCLKNPVTAFVRLAKGCYLGNVTEVAIPVRFLFVMLGPETQSDTYH--EIGRSIATLMSDQVFHDLAYYSESREDILMAINEFLDDTVVLPPGEWDKQLLIPVLLSQSKTMAKRRKQAKEINAIATQAAEEEDNPLKRTGRFCGGLIQDIKHRSKTYISDFKDGFNWQ-----CLLVTVFLYFAVFAPNVAFGGLLAEKTDQWLGVSEVIFASCFCGLLFALFSGQPLIIIGATGPVMVFEQTIFKFCEQSNIEFLPWRCWIGFWVLVILFLVVAFEGCFLVRYFTRFTEELFACLISLIFIYEAINFLYKVFKKNPLSRDPVTNLTNIDPY-----------IKENIVPVTG--------------EPNTALLCAILMFGTYFVAFYMRKFRNSHFFGKKARRLVSDFGIAIAMITMVIIDVAI-RDTVITPKISIGDVTKVGFHPTLKTKRGWFINPMGLVDSMKAGWVFAAIIPALFVGILLFMETELTGVLINKKENCLQKRPGYNMDLLLMGVITLICSLFGLPWMCPATVRSVSHFNALSVWS----TSHAPGEKPYLVEVREQRITNILIHVLTGMSILLAPV-LHHVPVPVLFGVLLYLGLSSLSNLQLINRLIMMLMPPKHHPDVRYVRKVPTAKIH---GYTLIQLACLLVLMAVKLTILAPSFPFFII 888
BLAST of slc4a-8 vs. Ensembl Nematostella
Match: EDO27089 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7TA82]) HSP 1 Score: 50.447 bits (119), Expect = 1.382e-7 Identity = 33/101 (32.67%), Postives = 59/101 (58.42%), Query Frame = 2
Query: 1427 IISQAIGGLCFGFFSGQXXXXXXXXXXXXXFVKIISSICNDYDLDFFAMYSCVGLINSLLLILYAMFDISKLMRWSTRSSEEIFALFVAISFVVDAVKDIY 1729
++ AIGG+ F FSGQPLIIL T P+ +F +I+ + C L++ + +G+ L ++ + D S ++ + TR +EE FA +AI ++ + K ++
Sbjct: 5 MLGGAIGGILFALFSGQPLIILGATGPMLVFEEIVYTFCERVGLEYLSFRLWIGIWTMLFCLILVVTDASAMICYFTRFTEETFATLIAIIYIYEGFKKLF 105
BLAST of slc4a-8 vs. Ensembl Medaka
Match: slc4a11 (solute carrier family 4 member 11 [Source:NCBI gene;Acc:101165271]) HSP 1 Score: 572.392 bits (1474), Expect = 0.000e+0 Identity = 330/796 (41.46%), Postives = 508/796 (63.82%), Query Frame = 2
Query: 491 QNADETEDDSVPCLFLSRLEK-IPMKDFSAEVRATLDIQKFLKEAVLLLDMSGSCLEEIIDSMLLTILANEVTDAKVSLEALV--EEAKKTLFIQSSYLTYTYQRLAKTIRGLSLSETEGLMTDQSWLCTMCSLNCIHKRHVAIARLNNPVNMGRSSEGIYFIILVVTPTKEKGTKSDIELGRTFATIFADVEFRQQLLFSESVEQFKELLQYHSGDLMEDQAMNRRKSLKVQEVMNQAFHFDKK----YLVGSGIVSDFKKRFPVYLMDFRDGFRGKG-TIRKVISATIFLYFACLLPSIAFGVLNYNNTEGKIDVRRVIISQAIGGLCFGFFSGQXXXXXXXXXXXXXFVKIISSICNDYDLDFFAMYSCVGLINSLLLILYAMFDISKLMRWSTRSSEEIFALFVAISFVVDAVKDIYKEFSTHYFSCYLSANNQSTEHLRLSRFKRAFSGIISNIXXXXXXXXXXXXXXXXXXCQREVSILYLFLVAGTVWLAIQLFTSTKTPFLNNAKREMLTDFALPLAVVIMSLIGTYLFKEIEMQPFVIVEEKVKFEASGILKLPWLAIAGAIALAFPLSLLMFMDQNISSAMVNSPANKLKKGSSYHWDLLVVALINAGLSVFGLPLVHGALPHSPLHVKALADLEERIDTAHHVHQTIVKVRETRITSILSHVFIGISLQMLPIPLIYIPVAVLDGLFVYMAVTTLYGNQFFERILLLFTEQSAYPPSHYLRRVPQRKLHIFTGLQIFQLAGLCLLGFSPSPYLKMGFPLLLLFHMVFRHQVVPRVIDEKYLNALD 2854
Q + T+ D C+ L+ + + + +F EVRA D+ FL +A +LLD + + L++++ ML + V + E EE LF + L++TI+G++ + T G+ QSWLC +C++ + +RHV I+RL P N G + + ++IL++ P+K K TK+ +ELGRTFAT+F+D+ FRQ+LL +++ E+FKE L + L A N++ + +E + H K + VG GI DF +R P Y DF DG G T+ K ++ IFLY A LLP+IAFG LN +T G+IDVR+ I+ Q+IGG+ + F+G PL+I LTTAPLA+F+ +I IC+DY+LDF A Y+C+GL N L LIL +F++S LM+ RS+EE+ ALF++I+FVVDAVK K F +Y N ++ + L F++ + N S + LN+ + C RE +L L L+ GT+W+ L+ ++PFL+ RE+L+D ALP++V++ S IG+Y+F +IE+ P V + F + +L + + A+ L F L+LL+F+DQNI ++ N+P N+L KG++YHWDL++ LIN +SV GLP +H A PHS LHV+ LA +E+R++ H +++TIV+V+ETR+TS+ +++FIG+SL +LP+PL +IP VL GLF+Y+A+T++ GNQ +R+ LL EQ++YPP+HY+R+VPQRK+H FT LQ+ QL LC G P PY+KM FPL+++F + R+ V+P +I+ KYL+ +D
Sbjct: 61 QISPGTDADDCGCVLLNTSRRYVKLMNFEEEVRALRDLDGFLAKASILLDETAASLDDVLKRML-----HHVGQDGHAYEPSCNFEEVMSLLFTDAGAQEVNVHLLSETIQGVTATAT-GIQYQQSWLCILCNVKHLQRRHVCISRLERPQNWGENCCEVRYVILILAPSKMKSTKTAMELGRTFATLFSDISFRQKLLETKTQEEFKEALLFQRHQLT---AANQQPTALGKEETDPRSHKPLKCKDFFKVGRGIYEDFCRRLPFYPSDFTDGIVGSNKTLLKYMTTAIFLYIAILLPAIAFGSLNDESTRGEIDVRKTIVGQSIGGIIYSLFAGSPLVIPLTTAPLAIFISVIRGICDDYNLDFPAFYACIGLWNCLFLILGGIFNVSLLMKLFKRSTEEVIALFISIAFVVDAVKGTVKIFQRYY-------NAPTSTNRSLEDFRQGGELLEGNRSEVAARLMLNALPETIIQCSRERPVLCLLLMLGTLWMGYTLYQFKRSPFLHAKVREVLSDCALPISVLLFSFIGSYIFSDIEL-PVFKVHNRPIFNVAPFERLSAMNVVSAMGLGFLLALLIFIDQNIVVSLTNAPENRLLKGTAYHWDLMLSGLINILMSVLGLPWMHAAFPHSTLHVRQLAFVEQRVEGGH-LYETIVQVKETRLTSLAANIFIGVSLLLLPVPLQWIPKPVLYGLFLYIALTSIDGNQMCDRMALLLKEQTSYPPTHYIRKVPQRKIHYFTFLQMMQLLVLCTFGMYPIPYMKMIFPLVMIFLIPIRNNVLPHIIEAKYLDIMD 838
BLAST of slc4a-8 vs. Ensembl Medaka
Match: slc4a11 (solute carrier family 4 member 11 [Source:NCBI gene;Acc:101165271]) HSP 1 Score: 572.392 bits (1474), Expect = 0.000e+0 Identity = 330/796 (41.46%), Postives = 508/796 (63.82%), Query Frame = 2
Query: 491 QNADETEDDSVPCLFLSRLEK-IPMKDFSAEVRATLDIQKFLKEAVLLLDMSGSCLEEIIDSMLLTILANEVTDAKVSLEALV--EEAKKTLFIQSSYLTYTYQRLAKTIRGLSLSETEGLMTDQSWLCTMCSLNCIHKRHVAIARLNNPVNMGRSSEGIYFIILVVTPTKEKGTKSDIELGRTFATIFADVEFRQQLLFSESVEQFKELLQYHSGDLMEDQAMNRRKSLKVQEVMNQAFHFDKK----YLVGSGIVSDFKKRFPVYLMDFRDGFRGKG-TIRKVISATIFLYFACLLPSIAFGVLNYNNTEGKIDVRRVIISQAIGGLCFGFFSGQXXXXXXXXXXXXXFVKIISSICNDYDLDFFAMYSCVGLINSLLLILYAMFDISKLMRWSTRSSEEIFALFVAISFVVDAVKDIYKEFSTHYFSCYLSANNQSTEHLRLSRFKRAFSGIISNIXXXXXXXXXXXXXXXXXXCQREVSILYLFLVAGTVWLAIQLFTSTKTPFLNNAKREMLTDFALPLAVVIMSLIGTYLFKEIEMQPFVIVEEKVKFEASGILKLPWLAIAGAIALAFPLSLLMFMDQNISSAMVNSPANKLKKGSSYHWDLLVVALINAGLSVFGLPLVHGALPHSPLHVKALADLEERIDTAHHVHQTIVKVRETRITSILSHVFIGISLQMLPIPLIYIPVAVLDGLFVYMAVTTLYGNQFFERILLLFTEQSAYPPSHYLRRVPQRKLHIFTGLQIFQLAGLCLLGFSPSPYLKMGFPLLLLFHMVFRHQVVPRVIDEKYLNALD 2854
Q + T+ D C+ L+ + + + +F EVRA D+ FL +A +LLD + + L++++ ML + V + E EE LF + L++TI+G++ + T G+ QSWLC +C++ + +RHV I+RL P N G + + ++IL++ P+K K TK+ +ELGRTFAT+F+D+ FRQ+LL +++ E+FKE L + L A N++ + +E + H K + VG GI DF +R P Y DF DG G T+ K ++ IFLY A LLP+IAFG LN +T G+IDVR+ I+ Q+IGG+ + F+G PL+I LTTAPLA+F+ +I IC+DY+LDF A Y+C+GL N L LIL +F++S LM+ RS+EE+ ALF++I+FVVDAVK K F +Y N ++ + L F++ + N S + LN+ + C RE +L L L+ GT+W+ L+ ++PFL+ RE+L+D ALP++V++ S IG+Y+F +IE+ P V + F + +L + + A+ L F L+LL+F+DQNI ++ N+P N+L KG++YHWDL++ LIN +SV GLP +H A PHS LHV+ LA +E+R++ H +++TIV+V+ETR+TS+ +++FIG+SL +LP+PL +IP VL GLF+Y+A+T++ GNQ +R+ LL EQ++YPP+HY+R+VPQRK+H FT LQ+ QL LC G P PY+KM FPL+++F + R+ V+P +I+ KYL+ +D
Sbjct: 63 QISPGTDADDCGCVLLNTSRRYVKLMNFEEEVRALRDLDGFLAKASILLDETAASLDDVLKRML-----HHVGQDGHAYEPSCNFEEVMSLLFTDAGAQEVNVHLLSETIQGVTATAT-GIQYQQSWLCILCNVKHLQRRHVCISRLERPQNWGENCCEVRYVILILAPSKMKSTKTAMELGRTFATLFSDISFRQKLLETKTQEEFKEALLFQRHQLT---AANQQPTALGKEETDPRSHKPLKCKDFFKVGRGIYEDFCRRLPFYPSDFTDGIVGSNKTLLKYMTTAIFLYIAILLPAIAFGSLNDESTRGEIDVRKTIVGQSIGGIIYSLFAGSPLVIPLTTAPLAIFISVIRGICDDYNLDFPAFYACIGLWNCLFLILGGIFNVSLLMKLFKRSTEEVIALFISIAFVVDAVKGTVKIFQRYY-------NAPTSTNRSLEDFRQGGELLEGNRSEVAARLMLNALPETIIQCSRERPVLCLLLMLGTLWMGYTLYQFKRSPFLHAKVREVLSDCALPISVLLFSFIGSYIFSDIEL-PVFKVHNRPIFNVAPFERLSAMNVVSAMGLGFLLALLIFIDQNIVVSLTNAPENRLLKGTAYHWDLMLSGLINILMSVLGLPWMHAAFPHSTLHVRQLAFVEQRVEGGH-LYETIVQVKETRLTSLAANIFIGVSLLLLPVPLQWIPKPVLYGLFLYIALTSIDGNQMCDRMALLLKEQTSYPPTHYIRKVPQRKIHYFTFLQMMQLLVLCTFGMYPIPYMKMIFPLVMIFLIPIRNNVLPHIIEAKYLDIMD 840
BLAST of slc4a-8 vs. Ensembl Medaka
Match: slc4a11 (solute carrier family 4 member 11 [Source:NCBI gene;Acc:101165271]) HSP 1 Score: 566.614 bits (1459), Expect = 0.000e+0 Identity = 332/813 (40.84%), Postives = 516/813 (63.47%), Query Frame = 2
Query: 482 YCLQNADETEDDSVPCLFLSRLEK-IPMKDFSAEVRATLDIQKFLKEAVLLLDMSGSCLEEIIDSMLLTILAN-----------EV-----TDAKVSLEALVEEAKKTLFIQSSYLTYTYQRLAKTIRGLSLSETEGLMTDQSWLCTMCSLNCIHKRHVAIARLNNPVNMGRSSEGIYFIILVVTPTKEKGTKSDIELGRTFATIFADVEFRQQLLFSESVEQFKELLQYHSGDLMEDQAMNRRKSLKVQEVMNQAFHFDKK----YLVGSGIVSDFKKRFPVYLMDFRDGFRGKG-TIRKVISATIFLYFACLLPSIAFGVLNYNNTEGKIDVRRVIISQAIGGLCFGFFSGQXXXXXXXXXXXXXFVKIISSICNDYDLDFFAMYSCVGLINSLLLILYAMFDISKLMRWSTRSSEEIFALFVAISFVVDAVKDIYKEFSTHYFSCYLSANNQSTEHLRLSRFKRAFSGIISNIXXXXXXXXXXXXXXXXXXCQREVSILYLFLVAGTVWLAIQLFTSTKTPFLNNAKREMLTDFALPLAVVIMSLIGTYLFKEIEMQPFVIVEEKVKFEASGILKLPWLAIAGAIALAFPLSLLMFMDQNISSAMVNSPANKLKKGSSYHWDLLVVALINAGLSVFGLPLVHGALPHSPLHVKALADLEERIDTAHHVHQTIVKVRETRITSILSHVFIGISLQMLPIPLIYIPVAVLDGLFVYMAVTTLYGNQFFERILLLFTEQSAYPPSHYLRRVPQRKLHIFTGLQIFQLAGLCLLGFSPSPYLKMGFPLLLLFHMVFRHQVVPRVIDEKYLNALD 2854
Y Q + T+ D C+ L+ + + + +F EVRA D+ FL +A +LLD + + L++++ ML + + EV TDA + + + ++ +F +L L++TI+G++ + T G+ QSWLC +C++ + +RHV I+RL P N G + + ++IL++ P+K K TK+ +ELGRTFAT+F+D+ FRQ+LL +++ E+FKE L + L A N++ + +E + H K + VG GI DF +R P Y DF DG G T+ K ++ IFLY A LLP+IAFG LN +T G+IDVR+ I+ Q+IGG+ + F+G PL+I LTTAPLA+F+ +I IC+DY+LDF A Y+C+GL N L LIL +F++S LM+ RS+EE+ ALF++I+FVVDAVK K F +Y N ++ + L F++ + N S + LN+ + C RE +L L L+ GT+W+ L+ ++PFL+ RE+L+D ALP++V++ S IG+Y+F +IE+ P V + F + +L + + A+ L F L+LL+F+DQNI ++ N+P N+L KG++YHWDL++ LIN +SV GLP +H A PHS LHV+ LA +E+R++ H +++TIV+V+ETR+TS+ +++FIG+SL +LP+PL +IP VL GLF+Y+A+T++ GNQ +R+ LL EQ++YPP+HY+R+VPQRK+H FT LQ+ QL LC G P PY+KM FPL+++F + R+ V+P +I+ KYL+ +D
Sbjct: 60 YDNQISPGTDADDCGCVLLNTSRRYVKLMNFEEEVRALRDLDGFLAKASILLDETAASLDDVLKRMLHHVGQDGHAYEPSCNFEEVMSLLFTDAGA--QEVNDNSQSFVFFDDVHL------LSETIQGVTATAT-GIQYQQSWLCILCNVKHLQRRHVCISRLERPQNWGENCCEVRYVILILAPSKMKSTKTAMELGRTFATLFSDISFRQKLLETKTQEEFKEALLFQRHQLT---AANQQPTALGKEETDPRSHKPLKCKDFFKVGRGIYEDFCRRLPFYPSDFTDGIVGSNKTLLKYMTTAIFLYIAILLPAIAFGSLNDESTRGEIDVRKTIVGQSIGGIIYSLFAGSPLVIPLTTAPLAIFISVIRGICDDYNLDFPAFYACIGLWNCLFLILGGIFNVSLLMKLFKRSTEEVIALFISIAFVVDAVKGTVKIFQRYY-------NAPTSTNRSLEDFRQGGELLEGNRSEVAARLMLNALPETIIQCSRERPVLCLLLMLGTLWMGYTLYQFKRSPFLHAKVREVLSDCALPISVLLFSFIGSYIFSDIEL-PVFKVHNRPIFNVAPFERLSAMNVVSAMGLGFLLALLIFIDQNIVVSLTNAPENRLLKGTAYHWDLMLSGLINILMSVLGLPWMHAAFPHSTLHVRQLAFVEQRVEGGH-LYETIVQVKETRLTSLAANIFIGVSLLLLPVPLQWIPKPVLYGLFLYIALTSIDGNQMCDRMALLLKEQTSYPPTHYIRKVPQRKIHYFTFLQMMQLLVLCTFGMYPIPYMKMIFPLVMIFLIPIRNNVLPHIIEAKYLDIMD 851
BLAST of slc4a-8 vs. Ensembl Medaka
Match: SLC4A11 (sodium bicarbonate transporter-like protein 11 [Source:NCBI gene;Acc:101168050]) HSP 1 Score: 503.056 bits (1294), Expect = 4.072e-166 Identity = 291/685 (42.48%), Postives = 429/685 (62.63%), Query Frame = 2
Query: 890 IHKRHVAIARLNNPVNMGRSSEGIYFIILVVTPTKEKGTKSDIELGRTFATIFADVEFRQQLLFSESVEQFKELLQYHSGDLMEDQAMNRRKSLKVQEVMNQAFHFDKK------YLVGSGIVSDFKKRFPVYLMDFRDGFRGKG-TIRKVISATIFLYFACLLPSIAFGVLNYNNTEGKIDVRRVIISQAIGGLCFGFFSGQXXXXXXXXXXXXXFVKIISSICNDYDLDFFAMYSCVGLINSLLLILYAMFDISKLMRWSTRSSEEIFALFVAISFVVDAVKDIYKEFSTHYFSCYL------------------SANNQS---TEHLR--LSRFKRAFSGIISNIXXXXXXXXXXXXXXXXXXCQREVSILYLFLVAGTVWLAIQLFTSTKTPFLNNAKREMLTDFALPLAVVIMSLIGTYLFKEIEMQPFVIVEEKVKFEASGILKLPWLAIAGAIALAFPLSLLMFMDQNISSAMVNSPANKLKKGSSYHWDLLVVALINAGLSVFGLPLVHGALPHSPLHVKALADLEERIDTAHHVHQTIVKVRETRITSILSHVFIGISLQMLPIPLIYIPVAVLDGLFVYMAVTTLYGNQFFERILLLFTEQSAYPPSHYLRRVPQRKLHIFTGLQIFQLAGLCLLGFSPSPYLKMGFPLLLLFHMVFRHQVVPRVIDEKYLNALD 2854
+ +R V IARL+ P N G + ++IL++ P + K TK+ IELGRTFAT+F+D+ FR++LL + ++FK+ L L E A + V+EV K + G G+ +D ++R P+Y DF DG GK + K I+ IFLY A LLP+IAFG LN +T G+IDV++ I+ Q+IGG+ + F+G PL+I LTTAPLA+F+ II IC+DY+LDF A Y+C+GL N L+L +F++S LM+ RS+EE+ ALF++I+FV DA+K K F HYF + ANNQ+ TEH + +S+F++A + ++ + C RE IL L L+ GT+WL L+ ++P+LN+ RE+++D ALP++V+I S IG+YLF +I++ P V + F+ KL +A+ A+ L F L+LL+F+DQNI ++ + P +KL KG+++HWDL++ IN +S GLP +H A PHS LH + LA +E ++ H +H TIV V+ETR+TS+++++ IG+S MLPIPL +IP VL GLF+Y+A T+L GNQ +R+ LL EQ++YPP+HY+RRVPQRK+H FT LQ+ QL LC G P PY+KM FPLL++ + R ++PR+ID KYL+ +D
Sbjct: 18 LQRRQVCIARLDKPQNWGVNCAEARYVILILAPPRTKSTKTAIELGRTFATMFSDISFREKLLDPRTQDEFKQELVSQRRQLSEVNA-----NTIVEEVEESDPRRGKPLECRDFFKAGRGVYNDLRRRLPLYPSDFTDGITGKDRCLVKYITTAIFLYIAILLPAIAFGSLNDESTRGEIDVQKTIVGQSIGGVIYSLFAGSPLVIPLTTAPLAIFISIIRGICDDYNLDFEAFYACIGLWNCFFLVLGGLFNVSLLMKLFKRSTEEVIALFISIAFVGDAIKGTIKIFD-HYFHGPILATTNSSAVLQQINEILEKANNQTPHLTEHHKGDMSQFEQAETQVL------------VFLPETLVICTRERPILCLLLMLGTLWLGYALYLMKRSPYLNDKIREVVSDCALPISVMIFSFIGSYLFIDIQL-PVFNVHDGPVFKYPEFEKLSGMAVLSAVGLGFLLALLIFIDQNIVISLTHVPEHKLLKGTTFHWDLVLTGFINILMSCLGLPWMHAAFPHSSLHARQLAKVEHHLENGH-LHSTIVSVKETRVTSLVANILIGLSAFMLPIPLQWIPKPVLYGLFLYVAATSLDGNQMVDRMTLLLKEQTSYPPTHYIRRVPQRKVHYFTALQMLQLIILCAFGMYPLPYMKMVFPLLMILLVPVRTGLLPRLIDAKYLDIMD 682
BLAST of slc4a-8 vs. Ensembl Medaka
Match: slc4a3 (solute carrier family 4 member 3 [Source:NCBI gene;Acc:101164449]) HSP 1 Score: 199.519 bits (506), Expect = 6.117e-52 Identity = 161/554 (29.06%), Postives = 280/554 (50.54%), Query Frame = 2
Query: 1229 SGIVSDFKKRFPVYLMDFRDGFRGKGTIRKVISATIFLYFACLLPSIAFGVLNYNNTEGKIDVRRVIISQAIGGLCFGFFSGQXXXXXXXXXXXXXFVKIISSICNDYDLDFFAMYSCVG--LINSLLLILYAMFDISKLMRWSTRSSEEIFALFVAISFVVDAVKDIYKEFSTHYFSCYLSANNQSTEHLRLSRFKRAFSGIISNIXXXXXXXXXXXXXXXXXXCQREVSILYLFLVAGTVWLAIQLFTSTKTPFLNNAKREMLTDFALPLAVVI-----MSLIGTYLFKEIEMQPFVIV--EEKVKFEASGILKLP---WLAIAGAIALAFPLSLLMFMDQNISSAMVNSPANKLKKGSSYHWDLLVVALINAGLSVFGLPLVHGALPHSPLHVKALADLEERIDTAHHVHQTIVKVRETRITSILSHVFIGISLQMLPIPLIYIPVAVLDGLFVYMAVTTLYGNQFFERILLLFTEQSAYPPSHYLRRVPQRKLHIFTGLQIFQLAGLCLLGFSPSPYLKMGFPLLLLFHMVFRHQVVPRVIDEKYLNALD 2854
G++ D ++R+P+Y+ DF+D + I+A IF+YFA L P+I FG L TEG + V +I+S A G+ F F+GQPL+I+ + PL +F + C Y ++ +G LI +L+I+ A + S L+R+ + ++EIFA +++ F+ + ++K F H + + + F + I + Q ++L L L+ GT ++A L + FL R ++ DF +P+++++ S+ TY K F + +++ F + K P W+ + ++ A + +L+FM+ I+S +V+ +L KGS +H DLL++ ++ A +FGLP + A S HV AL + + TA I +V+E R+T +L V +G+S+ M + L IP+AVL G+F+YM VT+L G Q +ERI L+ T +P Y+ +V ++++FT I QL + L S + + FP +L+ + R ++ R+ +E+ L ALD
Sbjct: 705 GGLIHDIRRRYPLYISDFKDALD-----MQCIAAVIFIYFAALSPTITFGGLLGEKTEGMMGVTELIVSTATLGVLFSLFAGQPLLIIGFSGPLLVFEEAYYKFCQAYKFEYLTGRVWIGFWLIGIVLVIVAA--EGSFLVRYISPFTQEIFAFLISLIFIYETFSKLFKVFKEHPLMAVYPTDTTAA-----TGFPNEDNLIFN---------------------QPNTALLSLVLMMGTFFIAFFLRKFRNSRFLGGKARRIIGDFGIPISILVSVLVDYSITDTYTQKLNVPSGFSVTSPDKRGWFISPFGDKQPFPTWM-MGASVVPALLVFILIFMETQITSLIVSKKERRLIKGSGFHLDLLLIVILGAICPLFGLPWLTAATVRSVTHVNALTVMSKA--TAPGEKPMIQEVKEQRLTGLLVAVLVGMSIVMTDV-LRLIPLAVLFGIFLYMGVTSLTGIQLYERITLMVTPAKHHPDHIYVTKVKTWRMNMFT---IIQLTCIVALWVVKSTVVSLAFPFILIMTVPLRRLILSRIFEERELQALD 1218
BLAST of slc4a-8 vs. Planmine SMEST
Match: SMESG000009949.1 (SMESG000009949.1) HSP 1 Score: 1697.56 bits (4395), Expect = 0.000e+0 Identity = 913/915 (99.78%), Postives = 914/915 (99.89%), Query Frame = 2
Query: 119 MSDSDLGIQTSLEEIPLKCNLKRISXXXXXXXXXXDTVGHNIYSSRRPSSLHQTTFSGRNYYSMPTGEQEVTIKDNRTSISSHLFXXXXXXXXXXXXXXXXXXASNVSVDNMSNISGSTLAYCLQNADETEDDSVPCLFLSRLEKIPMKDFSAEVRATLDIQKFLKEAVLLLDMSGSCLEEIIDSMLLTILANEVTDAKVSLEALVEEAKKTLFIQSSYLTYTYQRLAKTIRGLSLSETEGLMTDQSWLCTMCSLNCIHKRHVAIARLNNPVNMGRSSEGIYFIILVVTPTKEKGTKSDIELGRTFATIFADVEFRQQLLFSESVEQFKELLQYHSGDLMEDQAMNRRKSLKVQEVMNQAFHFDKKYLVGSGIVSDFKKRFPVYLMDFRDGFRGKGTIRKVISATIFLYFACLLPSIAFGVLNYNNTEGKIDVRRVIISQAIGGLCFGFFSGQXXXXXXXXXXXXXFVKIISSICNDYDLDFFAMYSCVGLINSLLLILYAMFDISKLMRWSTRSSEEIFALFVAISFVVDAVKDIYKEFSTHYFSCYLSANNQSTEHLRLSRFKRAFSGIISNIXXXXXXXXXXXXXXXXXXCQREVSILYLFLVAGTVWLAIQLFTSTKTPFLNNAKREMLTDFALPLAVVIMSLIGTYLFKEIEMQPFVIVEEKVKFEASGILKLPWLAIAGAIALAFPLSLLMFMDQNISSAMVNSPANKLKKGSSYHWDLLVVALINAGLSVFGLPLVHGALPHSPLHVKALADLEERIDTAHHVHQTIVKVRETRITSILSHVFIGISLQMLPIPLIYIPVAVLDGLFVYMAVTTLYGNQFFERILLLFTEQSAYPPSHYLRRVPQRKLHIFTGLQIFQLAGLCLLGFSPSPYLKMGFPLLLLFHMVFRHQVVPRVIDEKYLNALDKPI 2863
MSDSDLGIQTSLEEIPLK NLKRISNEINNHNHEIDTVGHNIYSSRRPSSLHQTTFSGRNYYSMPTGEQEVTIKDNRTSISSHLFLLPPSPGRRLSRQRQGSSASNVSVDNMSNISGSTLAYCLQNADETEDDSVPCLFLSRLEKIPMKDFSAEVRATLDIQKFLKEAVLLLDMSGSCLEEIIDSMLLTILANEVTDAKVSLEALVEEAKKTLFIQSSYLTYTYQRLAKTIRGLSLSETEGLMTDQSWLCTMCSLNCIHKRHVAIARLNNPVNMGRSSEGIYFIILVVTPTKEKGTKSDIELGRTFATIFADVEFRQQLLFSESVEQFKELLQYHSGDLMEDQAMNRRKSLKVQEVMNQAFHFDKKYLVGSGIVSDFKKRFPVYLMDFRDGFRGKGTIRKVISATIFLYFACLLPSIAFGVLNYNNTEGKIDVRRVIISQAIGGLCFGFFSGQPLIILLTTAPLALFVKIISSICNDYDLDFFAMYSCVGLINSLLLILYAMFDISKLMRWSTRSSEEIFALFVAISFVVDAVKDIYKEFSTHYFSCYLSANNQST+HLRLSRFKRAFSGIISNISISLTQTNLNSSLYSSNSCQREVSILYLFLVAGTVWLAIQLFTSTKTPFLNNAKREMLTDFALPLAVVIMSLIGTYLFKEIEMQPFVIVEEKVKFEASGILKLPWLAIAGAIALAFPLSLLMFMDQNISSAMVNSPANKLKKGSSYHWDLLVVALINAGLSVFGLPLVHGALPHSPLHVKALADLEERIDTAHHVHQTIVKVRETRITSILSHVFIGISLQMLPIPLIYIPVAVLDGLFVYMAVTTLYGNQFFERILLLFTEQSAYPPSHYLRRVPQRKLHIFTGLQIFQLAGLCLLGFSPSPYLKMGFPLLLLFHMVFRHQVVPRVIDEKYLNALDKPI
Sbjct: 1 MSDSDLGIQTSLEEIPLKSNLKRISNEINNHNHEIDTVGHNIYSSRRPSSLHQTTFSGRNYYSMPTGEQEVTIKDNRTSISSHLFLLPPSPGRRLSRQRQGSSASNVSVDNMSNISGSTLAYCLQNADETEDDSVPCLFLSRLEKIPMKDFSAEVRATLDIQKFLKEAVLLLDMSGSCLEEIIDSMLLTILANEVTDAKVSLEALVEEAKKTLFIQSSYLTYTYQRLAKTIRGLSLSETEGLMTDQSWLCTMCSLNCIHKRHVAIARLNNPVNMGRSSEGIYFIILVVTPTKEKGTKSDIELGRTFATIFADVEFRQQLLFSESVEQFKELLQYHSGDLMEDQAMNRRKSLKVQEVMNQAFHFDKKYLVGSGIVSDFKKRFPVYLMDFRDGFRGKGTIRKVISATIFLYFACLLPSIAFGVLNYNNTEGKIDVRRVIISQAIGGLCFGFFSGQPLIILLTTAPLALFVKIISSICNDYDLDFFAMYSCVGLINSLLLILYAMFDISKLMRWSTRSSEEIFALFVAISFVVDAVKDIYKEFSTHYFSCYLSANNQSTDHLRLSRFKRAFSGIISNISISLTQTNLNSSLYSSNSCQREVSILYLFLVAGTVWLAIQLFTSTKTPFLNNAKREMLTDFALPLAVVIMSLIGTYLFKEIEMQPFVIVEEKVKFEASGILKLPWLAIAGAIALAFPLSLLMFMDQNISSAMVNSPANKLKKGSSYHWDLLVVALINAGLSVFGLPLVHGALPHSPLHVKALADLEERIDTAHHVHQTIVKVRETRITSILSHVFIGISLQMLPIPLIYIPVAVLDGLFVYMAVTTLYGNQFFERILLLFTEQSAYPPSHYLRRVPQRKLHIFTGLQIFQLAGLCLLGFSPSPYLKMGFPLLLLFHMVFRHQVVPRVIDEKYLNALDKPI 915
BLAST of slc4a-8 vs. Planmine SMEST
Match: SMESG000061700.1 (SMESG000061700.1) HSP 1 Score: 947.577 bits (2448), Expect = 0.000e+0 Identity = 476/804 (59.20%), Postives = 612/804 (76.12%), Query Frame = 2
Query: 446 DNMSNISGSTLAYCLQNADETEDDSVPCLFLSRLEKIPMKDFSAEVRATLDIQKFLKEAVLLLDMSGSCLEEIIDSMLLTILANEVTDAKVSLEALVEEAKKTLFIQSSYLTYTYQRLAKTIRGLSLSETEGLMTDQSWLCTMCSLNCIHKRHVAIARLNNPVNMGRSSEGIYFIILVVTPTKEKGTKSDIELGRTFATIFADVEFRQQLLFSESVEQFKELLQYHSGDLMEDQAMNRRKSLKVQEVMNQAFHFDKKYLVGSGIVSDFKKRFPVYLMDFRDGFRGKGTIRKVISATIFLYFACLLPSIAFGVLNYNNTEGKIDVRRVIISQAIGGLCFGFFSGQXXXXXXXXXXXXXFVKIISSICNDYDLDFFAMYSCVGLINSLLLILYAMFDISKLMRWSTRSSEEIFALFVAISFVVDAVKDIYKEFSTHYFSCYLSANNQSTEHLRLSRFKRAFSGIISNIXXXXXXXXXXXXXXXXXXCQREVSILYLFLVAGTVWLAIQLFTSTKTPFLNNAKREMLTDFALPLAVVIMSLIGTYLFKEIEMQPFVIVEEKVKFEASGILKLPWLAIAGAIALAFPLSLLMFMDQNISSAMVNSPANKLKKGSSYHWDLLVVALINAGLSVFGLPLVHGALPHSPLHVKALADLEERIDTAHHVHQTIVKVRETRITSILSHVFIGISLQMLPIPLIYIPVAVLDGLFVYMAVTTLYGNQFFERILLLFTEQSAYPPSHYLRRVPQRKLHIFTGLQIFQLAGLCLLGFSPSPYLKMGFPLLLLFHMVFRHQVVPRVIDEKYLNALDK 2857
DN+S +SG + L+N + P L LSRLEK+P+KDFS+EVRA+LDI+KF+KE+VL L+M +EEII+ ML+ IL E+TD ++SLE ++EAK LF+ +S+LTY+YQRLAKTI+G+S+ +TEGL DQSW+ M +L +HKRH+AIARL+ P N+GRS+E ++FIILV+ PTKEKGTKS+IELGRTF+TI AD++FRQQLL E+ + F+ +LQ+ + L E Q + R++S+KV EVM+QAF K+ +G GIV D K+R P YL D+ DGF+G TIRKV S T FLYF+CLLPSIAFGVLN NNT+ KIDV+RVIISQAIGGL FG GQPLI++LTTAPLAL+ KII +I +Y +DF AM++C G+ N++ L++Y++ D+ KLM+WST+S+EE+FA FVAI+F VDA KD+YKEF+ HY C ++ LS F I S +S N +S C R+VS+LYL L GTVWLA LF TKTP+LN KRE+L DFALPLA+ IMS+IG LF++I + PF E+ +F+ + L W AI AL FPLSLL FMDQNI+S+MVNSP+NKLKKGS++HWDL +VALIN LS+FGLP +HGA+PHSPLHVKAL+D+EERID H VHQTIV+VRETR+TSILS++FI +SL +LP PL YIP+AVLDGLF++MAVT+LY NQF ERI LLFTEQSAYPPSHYLRRVPQRKLH+FT Q+ QL L LGFSPSPY+KMGFP++LL + RH+++P+ IDE ++NA+DK
Sbjct: 77 DNISMLSGVS-GIGLRNLSLFYNSPPPYLVLSRLEKLPLKDFSSEVRASLDIEKFVKESVLFLEMPCLSMEEIIERMLINILECEITD-EISLEMWIKEAKTKLFMHTSFLTYSYQRLAKTIKGISIDDTEGLAMDQSWITAMATLPNLHKRHLAIARLSTPANLGRSNENVHFIILVLNPTKEKGTKSEIELGRTFSTIMADIDFRQQLLMIENEQDFRSMLQFQARQLAETQKILRKRSVKVDEVMDQAFSVKTKFWIGGGIVGDIKRRIPHYLSDYCDGFKGANTIRKVFSTTSFLYFSCLLPSIAFGVLNGNNTDRKIDVKRVIISQAIGGLVFGILGGQPLIVMLTTAPLALYTKIIFTISTEYKIDFSAMFACTGIFNAVYLMIYSLTDMCKLMKWSTKSTEEVFAFFVAIAFTVDASKDVYKEFAQHY-QCAEENKVNNSIFKSLSNMSNPFQ-ITSTLSPMPDFHNSLHKGHSP--CHRDVSVLYLLLTIGTVWLAGHLFNFTKTPYLNARKRELLADFALPLAITIMSIIGALLFRDINLDPFYYDEKVFQFQPVNLPILGWKAILSCAALGFPLSLLFFMDQNIASSMVNSPSNKLKKGSTFHWDLFIVALINGFLSIFGLPWIHGAIPHSPLHVKALSDIEERIDIGHKVHQTIVRVRETRVTSILSNIFIALSLFLLPKPLSYIPIAVLDGLFIHMAVTSLYNNQFCERITLLFTEQSAYPPSHYLRRVPQRKLHLFTFFQLIQLIMLSALGFSPSPYMKMGFPIVLLLQIPIRHKIIPKFIDEIFINAMDK 874
BLAST of slc4a-8 vs. Planmine SMEST
Match: SMESG000039045.1 (SMESG000039045.1) HSP 1 Score: 907.131 bits (2343), Expect = 0.000e+0 Identity = 460/815 (56.44%), Postives = 623/815 (76.44%), Query Frame = 2
Query: 428 ASNVSVDNMSNISGSTLAYCLQNADETEDDSVPCLFLSRLEKIPMKDFSAEVRATLDIQKFLKEAVLLLDMSGSCLEEIIDSMLLTI--LANEVTDAKVSLEALVEEAKKTLFIQSSYLTYTYQRLAKTIRGLSLSETEGLMTDQSWLCTMCSLNCIHKRHVAIARLNNPVNMGRSSEGIYFIILVVTPTKEKGTKSDIELGRTFATIFADVEFRQQLLFSESVEQFKELLQYHSGDLMEDQAMNRRKSLKVQEVMNQAFHFDKKYLVGSGIVSDFKKRFPVYLMDFRDGFRGKGTIRKVISATIFLYFACLLPSIAFGVLNYNNTEGKIDVRRVIISQAIGGLCFGFFSGQXXXXXXXXXXXXXFVKIISSICNDYDLDFFAMYSCVGLINSLLLILYAMFDISKLMRWSTRSSEEIFALFVAISFVVDAVKDIYKEFSTHYFSCYLSANNQSTEHLRLSRFKRAFSGIISNIXXXXXXXXXXXXXXXXXXCQREVSILYLFLVAGTVWLAIQLFTSTKTPFLNNAKREMLTDFALPLAVVIMSLIGTYLFKEIEMQPFVI-VEEKVKFEASGILKLPWLAIAGAIALAFPLSLLMFMDQNISSAMVNSPANKLKKGSSYHWDLLVVALINAGLSVFGLPLVHGALPHSPLHVKALADLEERIDTAHHVHQTIVKVRETRITSILSHVFIGISLQMLPIPLIYIPVAVLDGLFVYMAVTTLYGNQFFERILLLFTEQSAYPPSHYLRRVPQRKLHIFTGLQIFQLAGLCLLGFSPSPYLKMGFPLLLLFHMVFRHQVVPRVIDEKYLNALDKPI 2863
S +S D +SN S +LA + ADE + +PCL L+RLEKIP+KDFS+EVRATLD++KFLKE VL+LDM + ++ I++ +L I LA +V+ + ++ + EAK LF+++ Y ++YQRLAKT++G+ ++E EGL TDQSW+ MCSL C+HKRHVAIARL PVN+GRSSEG+YF++LV+TP KEK TKSDIEL RTFAT+ +D+EFR QLLF+++ ++FKE+LQ H+ DL E+Q + RR+S+++ EVMNQAF +++K+ +G+GIV D +KR PVY+ D++DG +G GTIRK++SA FLYFACLLPS+AFGVL NT+GKI+V+RVI+SQ +GGLCF GQPLI++LTTAPL L++K+I +I Y L F+ M+S VG+ NS+ LILY++ D+SKLMRWSTRS+EEIFALF++I+F+VDAVKD+ K F Y + + N++ + + K G++++ ++ ++E +L+L L+ GTVWL I TKTPFLN++KR ++ D++LPLAV+IMS IG+YLFK+I++ F EE+ + ++ A+ A+ LAFPLSLL FMDQN++SAMVN P+NKLKKGS+YHWDLL+VA+IN LS+FGLP VHG LPHSPLHVKALADLEERID+ H +++TIVKVRETR+T ++SH+ IG+SL +LPIPLIY+P+AVLDGLFVYMA+T LYGNQ ER++LLFTEQ+AYPPSHYLRRVPQRK+H+FT LQ+ QL LC LGF+P+PY K+GFP+LLL M RH + P+ I Y++ALDKPI
Sbjct: 72 TSEMSTDTVSNFSIGSLARYYRTADE-NGEGLPCLVLARLEKIPIKDFSSEVRATLDVEKFLKEVVLILDMEANDVDTIVEHLLREIYPLAMDVSIGQ--MDTFITEAKNALFMKAHYENFSYQRLAKTLKGILINENEGLSTDQSWISAMCSLTCVHKRHVAIARLKTPVNLGRSSEGVYFVMLVITPKKEKDTKSDIELSRTFATLLSDMEFRSQLLFAQTEDEFKEMLQNHARDLAEEQRLYRRRSIRITEVMNQAFAYEEKFPLGNGIVDDLRKRIPVYISDYKDGIQGPGTIRKLVSAATFLYFACLLPSMAFGVLYDQNTDGKINVKRVILSQTVGGLCFALIGGQPLIVMLTTAPLTLYIKVIYAISAKYSLHFYTMFSWVGIFNSIFLILYSLLDLSKLMRWSTRSTEEIFALFISIAFIVDAVKDVLKVFYKSYVTTLV---NKTVPIVNTTLAK----GLLNS--------TNEFITITTEESRKENGLLFLLLLIGTVWLGIYFLNFTKTPFLNSSKRLLMADYSLPLAVLIMSFIGSYLFKDIKIDTFKTRSEEEFSIKFVNFSQISISAVFAALGLAFPLSLLFFMDQNVTSAMVNCPSNKLKKGSAYHWDLLIVAIINLVLSLFGLPWVHGTLPHSPLHVKALADLEERIDSGHRIYETIVKVRETRLTGLISHILIGLSLLLLPIPLIYVPIAVLDGLFVYMAITALYGNQLVERVILLFTEQAAYPPSHYLRRVPQRKVHLFTVLQLTQLGLLCALGFAPTPYAKIGFPILLLLQMPIRHWIFPKFISLTYIDALDKPI 868
BLAST of slc4a-8 vs. Planmine SMEST
Match: SMESG000039045.1 (SMESG000039045.1) HSP 1 Score: 892.878 bits (2306), Expect = 0.000e+0 Identity = 449/788 (56.98%), Postives = 609/788 (77.28%), Query Frame = 2
Query: 509 EDDSVPCLFLSRLEKIPMKDFSAEVRATLDIQKFLKEAVLLLDMSGSCLEEIIDSMLLTI--LANEVTDAKVSLEALVEEAKKTLFIQSSYLTYTYQRLAKTIRGLSLSETEGLMTDQSWLCTMCSLNCIHKRHVAIARLNNPVNMGRSSEGIYFIILVVTPTKEKGTKSDIELGRTFATIFADVEFRQQLLFSESVEQFKELLQYHSGDLMEDQAMNRRKSLKVQEVMNQAFHFDKKYLVGSGIVSDFKKRFPVYLMDFRDGFRGKGTIRKVISATIFLYFACLLPSIAFGVLNYNNTEGKIDVRRVIISQAIGGLCFGFFSGQXXXXXXXXXXXXXFVKIISSICNDYDLDFFAMYSCVGLINSLLLILYAMFDISKLMRWSTRSSEEIFALFVAISFVVDAVKDIYKEFSTHYFSCYLSANNQSTEHLRLSRFKRAFSGIISNIXXXXXXXXXXXXXXXXXXCQREVSILYLFLVAGTVWLAIQLFTSTKTPFLNNAKREMLTDFALPLAVVIMSLIGTYLFKEIEMQPFVI-VEEKVKFEASGILKLPWLAIAGAIALAFPLSLLMFMDQNISSAMVNSPANKLKKGSSYHWDLLVVALINAGLSVFGLPLVHGALPHSPLHVKALADLEERIDTAHHVHQTIVKVRETRITSILSHVFIGISLQMLPIPLIYIPVAVLDGLFVYMAVTTLYGNQFFERILLLFTEQSAYPPSHYLRRVPQRKLHIFTGLQIFQLAGLCLLGFSPSPYLKMGFPLLLLFHMVFRHQVVPRVIDEKYLNALDKPI 2863
+ + +PCL L+RLEKIP+KDFS+EVRATLD++KFLKE VL+LDM + ++ I++ +L I LA +V+ + ++ + EAK LF+++ Y ++YQRLAKT++G+ ++E EGL TDQSW+ MCSL C+HKRHVAIARL PVN+GRSSEG+YF++LV+TP KEK TKSDIEL RTFAT+ +D+EFR QLLF+++ ++FKE+LQ H+ DL E+Q + RR+S+++ EVMNQAF +++K+ +G+GIV D +KR PVY+ D++DG +G GTIRK++SA FLYFACLLPS+AFGVL NT+GKI+V+RVI+SQ +GGLCF GQPLI++LTTAPL L++K+I +I Y L F+ M+S VG+ NS+ LILY++ D+SKLMRWSTRS+EEIFALF++I+F+VDAVKD+ K F Y + + N++ + + K G++++ ++ ++E +L+L L+ GTVWL I TKTPFLN++KR ++ D++LPLAV+IMS IG+YLFK+I++ F EE+ + ++ A+ A+ LAFPLSLL FMDQN++SAMVN P+NKLKKGS+YHWDLL+VA+IN LS+FGLP VHG LPHSPLHVKALADLEERID+ H +++TIVKVRETR+T ++SH+ IG+SL +LPIPLIY+P+AVLDGLFVYMA+T LYGNQ ER++LLFTEQ+AYPPSHYLRRVPQRK+H+FT LQ+ QL LC LGF+P+PY K+GFP+LLL M RH + P+ I Y++ALDKPI
Sbjct: 67 KGEGLPCLVLARLEKIPIKDFSSEVRATLDVEKFLKEVVLILDMEANDVDTIVEHLLREIYPLAMDVSIGQ--MDTFITEAKNALFMKAHYENFSYQRLAKTLKGILINENEGLSTDQSWISAMCSLTCVHKRHVAIARLKTPVNLGRSSEGVYFVMLVITPKKEKDTKSDIELSRTFATLLSDMEFRSQLLFAQTEDEFKEMLQNHARDLAEEQRLYRRRSIRITEVMNQAFAYEEKFPLGNGIVDDLRKRIPVYISDYKDGIQGPGTIRKLVSAATFLYFACLLPSMAFGVLYDQNTDGKINVKRVILSQTVGGLCFALIGGQPLIVMLTTAPLTLYIKVIYAISAKYSLHFYTMFSWVGIFNSIFLILYSLLDLSKLMRWSTRSTEEIFALFISIAFIVDAVKDVLKVFYKSYVTTLV---NKTVPIVNTTLAK----GLLNS--------TNEFITITTEESRKENGLLFLLLLIGTVWLGIYFLNFTKTPFLNSSKRLLMADYSLPLAVLIMSFIGSYLFKDIKIDTFKTRSEEEFSIKFVNFSQISISAVFAALGLAFPLSLLFFMDQNVTSAMVNCPSNKLKKGSAYHWDLLIVAIINLVLSLFGLPWVHGTLPHSPLHVKALADLEERIDSGHRIYETIVKVRETRLTGLISHILIGLSLLLLPIPLIYVPIAVLDGLFVYMAITALYGNQLVERVILLFTEQAAYPPSHYLRRVPQRKVHLFTVLQLTQLGLLCALGFAPTPYAKIGFPILLLLQMPIRHWIFPKFISLTYIDALDKPI 837
BLAST of slc4a-8 vs. Planmine SMEST
Match: SMESG000012150.1 (SMESG000012150.1) HSP 1 Score: 520.776 bits (1340), Expect = 1.018e-169 Identity = 311/775 (40.13%), Postives = 460/775 (59.35%), Query Frame = 2
Query: 539 SRLEKIPMKDFSAEVRATLDIQKFLKEAVLLLDMSGSCLEEIIDSMLLTILANEVTDAKVSLEALVEEAKKTLFIQSSYLTYTYQRLAKTIRGLSLSETEGLMTDQSWLCTMCSLNCIHKRHVAIARLNNPVNMGRSSEGIYFIILVVTPTKEKGTKSDIELGRTFATIFADVEFRQQLLFSESVEQ-FKELLQYHSGDLMEDQAMNRRKSLKVQEVMNQAFHFDKKYLVGSGIVSDFKKRFPVYLMDFRDGFRGKGTIRKVISATIFLYFACLLPSIAFGVLNYNNTEGKIDVRRVIISQAIGGLCFGFFSGQXXXXXXXXXXXXXFVKIISSICNDYDLDFFAMYSCVGLINSLLLILYAMFDISKLMRWSTRSSEEIFALFVAISFVVDAVKDIYKEFSTHYFSCYLSANNQSTEHLRLSRFKRAFSGIISNIXXXXXXXXXXXXXXXXXXCQREVSILYLFLVAGTVWLAIQLFTSTKTPFLNNAKREMLTDFALPLAVVIMSLIGTYLFKEIEMQPFVIVE-EKVKFEASGILKLPWLAIAGAIALAFPLSLLMFMDQNISSAMVNSPANKLKKGSSYHWDLLVVALINAGLSVFGLPLVHGALPHSPLHVKALADLEERIDTAHHVHQTIVKVRETRITSILSHVFIGISLQMLPIPLIYIPVAVLDGLFVYMAVTTLYGNQFFERILLLFTEQSAYPPSHYLRRVPQRKLHIFTGLQIFQLAGLCLLGFSPSPYLKMGFPLLLLFHMVFRHQVVPRVIDEKYLNALDK 2857
+R +P S E+RA D +KF + ++L+ E I+ +L + + D L+ VE A L + ++ Y + AKTI G + + D SWL M SL+ I R V +P+NMG S + + +V+ P KEK K DIE R A I +D EFRQ + + E F++ + + L + + + +E + H K +G GI DF+ R P Y D++D F K +I K I+ L+F+ LLP+IAFG+LN T KI+V +++Q IGG+ F F GQP+II+LTT+PL+L + ++ + F Y+ +G+ N++ L +Y+ S +M++S RS+EE F LFV+++FV+D+VK K F +Y+ + N + A +G SC +E S+L++ L+ T+ L + L T+TPFLN+ R+ML++FALP++V+ MS IG+Y+FKE+++ F + A+ I +LP I A A+AFPLS+L FM+QNI+S++VN P NKLKKG +YH+DLLVV +IN LS+FGLP VHGALPHSP+HV ALA +EE ID + + Q +VKV ETRI I++++ IG + ++P PL+YIP VL+GLF+YMA T L+ NQ FER+LL TEQSAYPP+HYL+RVPQ+K+HIFT +Q QL LC+LGF+P Y+K+ FP +L+ + FRH + P++I +KYL+ALDK
Sbjct: 46 NRPTNVPF--LSEEIRARADAEKFSSTSSIVLNNYHIKTEIIVKDLLQKMFLTTIRDHD-KLDLSVELAFAELIVSNNDKEGDYFQFAKTINGFEHGKGGIMTADPSWLIAMASLSWIDHRLVGFTTTVHPINMGPSHSSVQMLAIVIAPIKEKTMKRDIETSRNIAAIMSDPEFRQTIRGYDVTETTFRDAFKETALRLQNSKPKSDNSEGEHEE--HSGLH--NKVSLGRGIYKDFRGRLPHYWSDYKDAFMDKNSIFKTITTIFVLFFSNLLPTIAFGMLNEYGTNHKINVASGLLAQLIGGVGFALFGGQPMIIMLTTSPLSLLIAAFYTMNSSLGYKFLQFYTWIGIFNAVYLFVYSFTGFSMIMKFSRRSTEETFELFVSVTFVIDSVKACTKSFHNYYYGGHCV--NATI----------AVTG----------------------SCTKEESLLFVLLLLSTMALGLWLNGLTETPFLNSMSRKMLSEFALPVSVLFMSFIGSYVFKEVKIHSFTAPPWRNISMIATDIRELPIAGIMLAAAVAFPLSILFFMEQNIASSIVNCPLNKLKKGPAYHYDLLVVGIINLILSIFGLPWVHGALPHSPMHVTALATIEEHIDEGNKIDQKVVKVTETRIPVIIANILIGCCIFLMPYPLLYIPAPVLNGLFLYMAFTALHSNQLFERLLLFITEQSAYPPNHYLKRVPQKKVHIFTSIQFLQLLLLCILGFTPITYVKLVFPFILILQLPFRHIIFPKIISKKYLDALDK 779 The following BLAST results are available for this feature:
BLAST of slc4a-8 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of slc4a-8 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of slc4a-8 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of slc4a-8 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of slc4a-8 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of slc4a-8 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of slc4a-8 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of slc4a-8 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of slc4a-8 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of slc4a-8 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of slc4a-8 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 1
BLAST of slc4a-8 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of slc4a-8 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of slc4a-8 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Cross References
External references for this transcript
Sequences
The following sequences are available for this feature:
transcript sequence >SMED30018199 ID=SMED30018199|Name=slc4a-8|organism=Schmidtea mediterranea sexual|type=transcript|length=2907bpback to top protein sequence of SMED30018199-orf-1 >SMED30018199-orf-1 ID=SMED30018199-orf-1|Name=SMED30018199-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=916bp MSDSDLGIQTSLEEIPLKCNLKRISNEINNHNHEIDTVGHNIYSSRRPSSback to top Aliases
The feature 'slc4a-8' has the following synonyms
Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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