Imidazolonepropionase

Overview
NameImidazolonepropionase
Smed IDSMED30018167
Length (bp)1360
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Imidazolonepropionase (SMED30018167) t-SNE clustered cells

Violin plots show distribution of expression levels for Imidazolonepropionase (SMED30018167) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Imidazolonepropionase (SMED30018167) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Imidazolonepropionase (SMED30018167) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30018167

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 5

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
pigment cellSMED30018167SMESG000058218.1 SmedASXL_010445SmedAsxl_ww_GCZZ01PMID:29158443
He et al., 2017		whole organism asexual adult RNA-sequencing evidence
gutSMED30018167SMESG000058218.1 dd_Smed_v4_5220_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30018167SMESG000058218.1 dd_Smed_v4_5220_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30018167SMESG000058218.1 dd_Smed_v4_5220_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30018167SMESG000058218.1 dd_Smed_v4_5220_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Imidazolonepropionase vs. Ensembl Human
Match: AMDHD1 (amidohydrolase domain containing 1 [Source:HGNC Symbol;Acc:HGNC:28577])

HSP 1 Score: 410.609 bits (1054), Expect = 2.046e-140
Identity = 202/383 (52.74%), Postives = 280/383 (73.11%), Query Frame = 2 
Query:  158 SICVDEVGNIKEINETEELIAKYS---YENLVDCKGGSIIPGFVDAHTHPVWAGDRVHEFEMKLAGASYLEIHNAGGGIHFSVDATTKASEISLEMSLKKRLMGMLQHGTTTVECKTGYGLLWETERKMLQVLTNMKKCLPIDISITFLPAHAIPKNSSSWQHTKDIVDNQIPKLKQCLISNELECNNIDVFCEKGIFEIEETKQILEAGKEIGLNINAHADELFPLGGTEMIAKLKAKAVSHLEEISKEGIKSLKEHGTTAVLLPTTAYLLSLKPPPVQDMIKRGVRCALGSDFNPNAFCLSMPIVMNLACVLYKMSMNEALLGATINGAYALGMEHRVGSLEIGKQADFLVLNETNWQHIIYQFGQSRDIIKFVVKKGNIV 1297
            S+ V + G IK I   + +  ++S   +E ++DC G  I+PG VDAHTHPVWAG+RVHEF MKLAGA+Y+EIH AGGGIHF+V+ T +A+E  L  SL++RL  M++ GTT VECK+GYGL  ETE KML+V+   ++ L I IS T+  AH++PK  ++ +   DI++N +PKLK+   + E+  +NIDVFCEKG+F+++ T++IL+ GK+IGL IN H DEL P+   E+ A+L A+A+SHLEE+S EGI ++     +A+LLPTTAY+L LK P  + M+  GV  ALGSDFNPNA+C SMP+VM+LACV  +MSM EAL  ATIN AYALG  H  GSLE+GKQ D +++N + W+H+IYQFG   ++I++V+ KG ++
Sbjct:   41 SLVVGKDGFIKAIGPADVIQRQFSGETFEEIIDCSGKCILPGLVDAHTHPVWAGERVHEFAMKLAGATYMEIHQAGGGIHFTVERTRQATEEELFRSLQQRLQCMMRAGTTLVECKSGYGLDLETELKMLRVIERARRELDIGISATYCGAHSVPKGKTATEAADDIINNHLPKLKELGRNGEIHVDNIDVFCEKGVFDLDSTRRILQRGKDIGLQINFHGDELHPMKAAELGAELGAQAISHLEEVSDEGIVAMATARCSAILLPTTAYMLRLKQPRARKMLDEGVIVALGSDFNPNAYCFSMPMVMHLACVNMRMSMPEALAAATINAAYALGKSHTHGSLEVGKQGDLIIINSSRWEHLIYQFGGHHELIEYVIAKGKLI 423
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BLAST of Imidazolonepropionase vs. Ensembl Celegans
Match: T12A2.1 (pep chromosome:WBcel235:III:6251811:6271282:1 gene:WBGene00020436.1 transcript:T12A2.1.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:T12A2.1)

HSP 1 Score: 382.104 bits (980), Expect = 1.082e-129
Identity = 196/431 (45.48%), Postives = 285/431 (66.13%), Query Frame = 2 
Query:   68 MYKLF-HNVSQIVT-----CSKFDLG-------ILNEKTSGKLSICVDEVGN---IKEINETEELIAKYSYE----NLVDCKGGSIIPGFVDAHTHPVWAGDRVHEFEMKLAGASYLEIHNAGGGIHFSVDATTKASEISLEMSLKKRLMGMLQHGTTTVECKTGYGLLWETERKMLQVLTNMKKCLPIDISITFLPAHAIPKNSSSWQHTKDIVDNQIPKLKQCLISNELE-CNNIDVFCEKGIFEIEETKQILEAGKEIGLNINAHADELFPLGGTEMIAKLKAKAVSHLEEISKEGIKSLKEHGTTAVLLPTTAYLLSLKPPPVQDMIKRGVRCALGSDFNPNAFCLSMPIVMNLACVLYKMSMNEALLGATINGAYALGMEHRVGSLEIGKQADFLVLNETNWQHIIYQFGQSRDIIKFVVKKGNIV 1297
            MY+L   N+ QIV       ++F +G       ILN+ +S  L I VD  G    I  +N  E  +     E     ++D  GG  IPGFVD H+HPV++GDRVHEF MKLAGA+Y+E+  AGGGI F+ + T +ASE  L    ++    ML+ GTTT+E K+GYGL  + E KML+VL      +P+++S TF  AHA+PK S+ ++ T+ I +  IPK++    +  L+   NIDVFCEKG+FE+E +++IL+ G+E G+ +N HA+EL  +GG EM AK+ A+A+SHLEEIS +GI+ + + G+ AVLLP+TA++L L PPP + +I+  V  ALGSDFNPNA+CL+MP++M+ ACV  K+SM EAL  AT+N A+++G     G++  G+ ADF++L+  +W+HIIY+     D+I +V+K GN+V
Sbjct:    1 MYRLLVKNLKQIVQIVDDDVTEFLIGDQMNNIKILND-SSNSLVILVDTNGKFSYIGNLNGAENKLKGEGVEMENLKIIDSNGGIAIPGFVDGHSHPVFSGDRVHEFAMKLAGATYMEVQQAGGGIMFTTNKTREASEQDLRKDFEELAKKMLRSGTTTLEAKSGYGLNVDAEMKMLRVLATENPNIPLEVSATFCGAHAVPKGSTEYEQTRMICEELIPKIEDEKRNGGLKNVENIDVFCEKGVFEVESSQKILKRGQEAGMAVNFHAEELKYIGGVEMGAKIGARAMSHLEEISDKGIRGMAQAGSVAVLLPSTAFILRLTPPPARKLIENNVIVALGSDFNPNAYCLAMPMIMHFACVTMKLSMPEALTAATLNSAHSIGRGKSHGAIAKGRNADFVILSANSWEHIIYRIAAHHDVINYVIKNGNVV 430
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BLAST of Imidazolonepropionase vs. Ensembl Zebrafish
Match: si:ch73-71d17.1 (si:ch73-71d17.1 [Source:NCBI gene;Acc:402826])

HSP 1 Score: 431.409 bits (1108), Expect = 8.949e-149
Identity = 203/387 (52.45%), Postives = 279/387 (72.09%), Query Frame = 2 
Query:  158 SICVDEVGNIKEINETEELIAKY---SYENLVDCKGGSIIPGFVDAHTHPVWAGDRVHEFEMKLAGASYLEIHNAGGGIHFSVDATTKASEISLEMSLKKRLMGMLQHGTTTVECKTGYGLLWETERKMLQVLTNMKKCLPIDISITFLPAHAIPKNSSSWQHTKDIVDNQIPKLKQCLISNELECNNIDVFCEKGIFEIEETKQILEAGKEIGLNINAHADELFPLGGTEMIAKLKAKAVSHLEEISKEGIKSLKEHGTTAVLLPTTAYLLSLKPPPVQDMIKRGVRCALGSDFNPNAFCLSMPIVMNLACVLYKMSMNEALLGATINGAYALGMEHRVGSLEIGKQADFLVLNETNWQHIIYQFGQSRDIIKFVVKKGNIVLFNN 1309
            S+ +   G IK +   + +  ++    ++N++D  G  ++PG VDAHTHPVWAGDRVHEF MKLAGA+Y+E+H AGGGIHF+V  T  ASE  L  +LK RL  M++ GTT VECK+GYGL  +TE KML+V+ + +K LPI IS T+  AHA+PK  +  + TKDIV  Q+PK+K    S +L+ +NIDVFCEKG+F++  T+ IL+AGK++GLNIN H DEL P+    + A+L A A+SHLEE++ +GI ++ +  T+AVLLPTTAY+L L PP  +DM+  GV  ALGSDFNPNA+C SMP+VM+LACV+ KMSM EAL  +TIN AYAL      GSLE+GKQ D +++N   W+H++YQFG  +++I++V+ KG+ V  N+
Sbjct:   42 SVLIGHDGLIKAVGPADVIETQFEGAKFDNVLDASGMCVLPGLVDAHTHPVWAGDRVHEFAMKLAGATYMEVHEAGGGIHFTVAHTRSASEQHLLAALKSRLERMMRAGTTLVECKSGYGLELDTEVKMLRVINSARKSLPIGISATYCGAHAVPKGKTMEEATKDIVAVQLPKIKHLSASGDLQVDNIDVFCEKGVFDLTSTRCILQAGKDMGLNINFHGDELHPMNSAHLGAELGALAISHLEEVTDDGIVAMAKSKTSAVLLPTTAYILRLTPPRARDMLDAGVIVALGSDFNPNAYCCSMPMVMHLACVMMKMSMPEALAASTINAAYALNRSQTHGSLEVGKQGDLVIVNAPRWEHLVYQFGGHQELIRYVIIKGDFVYEND 428
[Close]
BLAST of Imidazolonepropionase vs. Ensembl Zebrafish
Match: AMDHD1 (si:ch73-71d17.1 [Source:NCBI gene;Acc:402826])

HSP 1 Score: 429.483 bits (1103), Expect = 5.340e-148
Identity = 203/387 (52.45%), Postives = 278/387 (71.83%), Query Frame = 2 
Query:  158 SICVDEVGNIKEINETEELIAKY---SYENLVDCKGGSIIPGFVDAHTHPVWAGDRVHEFEMKLAGASYLEIHNAGGGIHFSVDATTKASEISLEMSLKKRLMGMLQHGTTTVECKTGYGLLWETERKMLQVLTNMKKCLPIDISITFLPAHAIPKNSSSWQHTKDIVDNQIPKLKQCLISNELECNNIDVFCEKGIFEIEETKQILEAGKEIGLNINAHADELFPLGGTEMIAKLKAKAVSHLEEISKEGIKSLKEHGTTAVLLPTTAYLLSLKPPPVQDMIKRGVRCALGSDFNPNAFCLSMPIVMNLACVLYKMSMNEALLGATINGAYALGMEHRVGSLEIGKQADFLVLNETNWQHIIYQFGQSRDIIKFVVKKGNIVLFNN 1309
            S+ +   G IK +   + +  ++    ++ ++D  G  ++PG VDAHTHPVWAGDRVHEF MKLAGA+Y+E+H AGGGIHF+V  T  ASE  L  +LK RL  M++ GTT VECK+GYGL  +TE KML+V+ + +K LPI IS T+  AHA+PK  +  + TKDIV  Q+PK+K    S +L+ +NIDVFCEKG+F++  T+ IL+AGK++GLNIN H DEL P+    + A+L A A+SHLEE++ +GI ++ +  T+AVLLPTTAY+L L PP  +DM+  GV  ALGSDFNPNA+C SMP+VM+LACV+ KMSM EAL  +TIN AYAL      GSLE+GKQ D +++N   W+H++YQFG  +++IK+V+ KG+ V  N+
Sbjct:   42 SVLIGHDGLIKAVGPADVIETQFEGAKFDKVLDASGMCVLPGLVDAHTHPVWAGDRVHEFAMKLAGATYMEVHEAGGGIHFTVAHTRSASEQHLLAALKSRLERMMRAGTTLVECKSGYGLELDTEVKMLRVINSARKSLPIGISATYCGAHAVPKGKTMEEATKDIVAVQLPKIKHLSASGDLQVDNIDVFCEKGVFDLTSTRCILQAGKDMGLNINFHGDELHPMNSAHLGAELGALAISHLEEVTYDGIVAMAKSKTSAVLLPTTAYILRLTPPRARDMLDAGVIVALGSDFNPNAYCCSMPMVMHLACVMMKMSMPEALAASTINAAYALNRSQTHGSLEVGKQGDLVIVNAPRWEHLVYQFGGHQELIKYVIIKGDFVYEND 428
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BLAST of Imidazolonepropionase vs. Ensembl Xenopus
Match: amdhd1 (amidohydrolase domain containing 1 [Source:NCBI gene;Acc:493273])

HSP 1 Score: 426.017 bits (1094), Expect = 1.639e-146
Identity = 223/419 (53.22%), Postives = 297/419 (70.88%), Query Frame = 2 
Query:   77 LFHNVSQIVT-CSKFDLGILNEKTSG-----KLSICVDEVGNIKEINETEELIAKYS---YENLVDCKGGSIIPGFVDAHTHPVWAGDRVHEFEMKLAGASYLEIHNAGGGIHFSVDATTKASEISLEMSLKKRLMGMLQHGTTTVECKTGYGLLWETERKMLQVLTNMKKCLPIDISITFLPAHAIPKNSSSWQHTKDIVDNQIPKLKQCLISNELECNNIDVFCEKGIFEIEETKQILEAGKEIGLNINAHADELFPLGGTEMIAKLKAKAVSHLEEISKEGIKSLKEHGTTAVLLPTTAYLLSLKPPPVQDMIKRGVRCALGSDFNPNAFCLSMPIVMNLACVLYKMSMNEALLGATINGAYALGMEHRVGSLEIGKQADFLVLNETNWQHIIYQFGQSRDIIKFVVKKGNIVLFN 1306
            L  N  QIV  CSK +  +L +         K S+ +   G IK++   E +  ++S   +EN++DC G  ++PGFVDAHTHPVWAGDRVHEF MKLAGA+Y++IH AGGGI+++V+ TT ASE  L  S K RL  ML+ GTT VECK+GYGL  ETE KML+V+    + L I +S T+  AH++PK  S+ + T DI+ N +P LKQ  ++ E+  +NIDVFCEKG+F+++ T++IL+AGK IGLN+N H DEL P+   E+ A+L A AVSHLEE+S +GI +L +   +AVLLPTTAY+L LK P  +DM+K GV  +LGSDFNPNA+C SMP+VM+LACV  KMS+ EAL  ATIN AYALG  H  GSLE+GKQ D +V+N + W+H+IYQFG  +++I++VV KG IV  N
Sbjct:    8 LLENAEQIVVVCSKEEEYLLEDGMQHLAILEKASLVIGNDGFIKDVGPAETIRNQFSNASFENIIDCSGKCVLPGFVDAHTHPVWAGDRVHEFAMKLAGATYMDIHKAGGGINYTVEHTTTASEEELFCSFKHRLERMLRAGTTLVECKSGYGLKLETELKMLRVIERAHQELDIAVSSTYCGAHSVPKGKSAQEATDDIIANHLPALKQMALNGEIHVDNIDVFCEKGVFDLDSTRKILQAGKAIGLNLNFHGDELNPMNSAELGAELGAHAVSHLEEVSDKGIAALAKAKCSAVLLPTTAYILRLKQPRARDMLKAGVIVSLGSDFNPNAYCFSMPMVMHLACVNMKMSLKEALAAATINAAYALGRAHTHGSLEVGKQGDVVVINASRWEHVIYQFGGHQELIEYVVIKGKIVYKN 426
[Close]
BLAST of Imidazolonepropionase vs. Ensembl Xenopus
Match: amdhd1 (amidohydrolase domain containing 1 [Source:NCBI gene;Acc:493273])

HSP 1 Score: 425.631 bits (1093), Expect = 2.199e-146
Identity = 223/419 (53.22%), Postives = 297/419 (70.88%), Query Frame = 2 
Query:   77 LFHNVSQIVT-CSKFDLGILNEKTSG-----KLSICVDEVGNIKEINETEELIAKYS---YENLVDCKGGSIIPGFVDAHTHPVWAGDRVHEFEMKLAGASYLEIHNAGGGIHFSVDATTKASEISLEMSLKKRLMGMLQHGTTTVECKTGYGLLWETERKMLQVLTNMKKCLPIDISITFLPAHAIPKNSSSWQHTKDIVDNQIPKLKQCLISNELECNNIDVFCEKGIFEIEETKQILEAGKEIGLNINAHADELFPLGGTEMIAKLKAKAVSHLEEISKEGIKSLKEHGTTAVLLPTTAYLLSLKPPPVQDMIKRGVRCALGSDFNPNAFCLSMPIVMNLACVLYKMSMNEALLGATINGAYALGMEHRVGSLEIGKQADFLVLNETNWQHIIYQFGQSRDIIKFVVKKGNIVLFN 1306
            L  N  QIV  CSK +  +L +         K S+ +   G IK++   E +  ++S   +EN++DC G  ++PGFVDAHTHPVWAGDRVHEF MKLAGA+Y++IH AGGGI+++V+ TT ASE  L  S K RL  ML+ GTT VECK+GYGL  ETE KML+V+    + L I +S T+  AH++PK  S+ + T DI+ N +P LKQ  ++ E+  +NIDVFCEKG+F+++ T++IL+AGK IGLN+N H DEL P+   E+ A+L A AVSHLEE+S +GI +L +   +AVLLPTTAY+L LK P  +DM+K GV  +LGSDFNPNA+C SMP+VM+LACV  KMS+ EAL  ATIN AYALG  H  GSLE+GKQ D +V+N + W+H+IYQFG  +++I++VV KG IV  N
Sbjct:    8 LLENAEQIVVVCSKEEEYLLEDGMQHLAILEKASLVIGNDGFIKDVGPAETIRNQFSNASFENIIDCSGKCVLPGFVDAHTHPVWAGDRVHEFAMKLAGATYMDIHKAGGGINYTVEHTTTASEEELFCSFKHRLERMLRAGTTLVECKSGYGLKLETELKMLRVIERAHQELDIAVSSTYCGAHSVPKGKSAQEATDDIIANHLPALKQMALNGEIHVDNIDVFCEKGVFDLDSTRKILQAGKAIGLNLNFHGDELNPMNSAELGAELGAHAVSHLEEVSDKGIAALAKAKCSAVLLPTTAYILRLKQPRARDMLKAGVIVSLGSDFNPNAYCFSMPMVMHLACVNMKMSLKEALAAATINAAYALGRAHTHGSLEVGKQGDVVVINASRWEHVIYQFGGHQELIEYVVIKGKIVYKN 426
[Close]
BLAST of Imidazolonepropionase vs. Ensembl Mouse
Match: Amdhd1 (amidohydrolase domain containing 1 [Source:MGI Symbol;Acc:MGI:1919011])

HSP 1 Score: 394.43 bits (1012), Expect = 2.342e-134
Identity = 195/383 (50.91%), Postives = 274/383 (71.54%), Query Frame = 2 
Query:  158 SICVDEVGNIKEINETEELIAKYS---YENLVDCKGGSIIPGFVDAHTHPVWAGDRVHEFEMKLAGASYLEIHNAGGGIHFSVDATTKASEISLEMSLKKRLMGMLQHGTTTVECKTGYGLLWETERKMLQVLTNMKKCLPIDISITFLPAHAIPKNSSSWQHTKDIVDNQIPKLKQCLISNELECNNIDVFCEKGIFEIEETKQILEAGKEIGLNINAHADELFPLGGTEMIAKLKAKAVSHLEEISKEGIKSLKEHGTTAVLLPTTAYLLSLKPPPVQDMIKRGVRCALGSDFNPNAFCLSMPIVMNLACVLYKMSMNEALLGATINGAYALGMEHRVGSLEIGKQADFLVLNETNWQHIIYQFGQSRDIIKFVVKKGNIV 1297
            S+ V   G IK +     +  ++S   +E  +DC G  ++PG VDAHTHPVWAG+RVHEF MKLAGA+Y++IH AGGGI+F+V+ T +ASE  L  S ++RL  M++ GTT VECK+GYGL  ETE KML+V+   ++ L + +S T+  AH++PK  ++ +   DI+ + +P+LK+   + +L  +NIDVFCEKG+F+++ T++ILE GK++GL IN H DEL P+   E+ A+L A+A+SHLEE+S EGI ++     +AVLLPTTAY+L LK P  + M+  GV  ALGSDFNPNA+C SMP+VM+LACV  +MSM EAL  ATIN AYALG  H  GSLE+GKQ D +++N + W+H+IYQFG   ++I +V+ KG ++
Sbjct:   41 SVVVGTDGLIKAVGPAAVIQKQFSGETFEERIDCSGKCVLPGLVDAHTHPVWAGERVHEFAMKLAGATYMDIHQAGGGINFTVEHTRQASEEELFCSFQQRLQCMMRAGTTLVECKSGYGLNLETELKMLRVIERARRELHLSLSATYCGAHSVPKGKTAVEAADDIISHHLPRLKELSRNGDLHVDNIDVFCEKGVFDLDTTRRILEGGKKMGLQINFHGDELHPMKAAELGAELGAQAISHLEEVSDEGIAAMAAARCSAVLLPTTAYMLRLKQPRARKMLDEGVIVALGSDFNPNAYCFSMPMVMHLACVNMRMSMPEALAAATINAAYALGKSHTHGSLEVGKQGDAIIINASRWEHLIYQFGGHHELIDYVITKGKVI 423
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BLAST of Imidazolonepropionase vs. UniProt/SwissProt
Match: sp|A7RX26|HUTI_NEMVE (Probable imidazolonepropionase OS=Nematostella vectensis OX=45351 GN=amdhd1 PE=3 SV=1)

HSP 1 Score: 433.721 bits (1114), Expect = 8.304e-149
Identity = 213/397 (53.65%), Postives = 281/397 (70.78%), Query Frame = 2 
Query:  119 DLGILNEKTSGKLSICVDEVGNIKEINETEELIAKY---SYENLVDCKGGSIIPGFVDAHTHPVWAGDRVHEFEMKLAGASYLEIHNAGGGIHFSVDATTKASEISLEMSLKKRLMGMLQHGTTTVECKTGYGLLWETERKMLQVLTNMKKCLPIDISITFLPAHAIPKNSSSWQHTKDIVDNQIPKLKQCLISNELECNNIDVFCEKGIFEIEETKQILEAGKEIGLNINAHADELFPLGGTEMIAKLKAKAVSHLEEISKEGIKSLKEHGTTAVLLPTTAYLLSLKPPPVQDMIKRGVRCALGSDFNPNAFCLSMPIVMNLACVLYKMSMNEALLGATINGAYALGMEHRVGSLEIGKQADFLVLNETNWQHIIYQFGQSRDIIKFVVKKGNIVL 1300
            ++ IL    +  +S+  DE G I+ I   +++  +Y   S+ + +D  G  ++PG +D HTHPVW GDRVHEF MKLAGASY+++H AGGGI+F+V+   KA+E  L   LK+RL  MLQ GTT VE K+GYGL  E E KML+V+   KK LPI+IS TF  AHAIP+ S++ Q   +I++ QIP L + + + EL+  NIDVFCEKG+FE+EET+ IL+AGK+ GL IN H DEL P+ G E+ A+L A+A+SHLEEIS+EGIK++ +     VLLPTTAY+L LKPPP + MI  GV  ALG+DFNPNA+CLSMP+ M+LAC + +MSM EAL GATIN A +LG     GSLE+GK AD +V+N   W+H+IYQ G   DII+ VVK G +V 
Sbjct:   30 NIAILEGSVNRGISVVADEFGKIECIGYDDDVEPQYNQCSFASEIDATGMCVLPGLIDGHTHPVWVGDRVHEFAMKLAGASYMDVHKAGGGINFTVEHVHKATEDELYEPLKQRLNRMLQCGTTLVEAKSGYGLNTENEMKMLKVIERAKKELPIEISSTFCGAHAIPRGSTAKQAADNIINEQIPTLVKAIKAGELDVENIDVFCEKGVFEVEETRVILQAGKDAGLAINFHGDELHPIKGAELGAELGARAISHLEEISEEGIKAMSKSSVIGVLLPTTAYILRLKPPPARAMIDAGVAIALGTDFNPNAYCLSMPLTMHLACCILRMSMTEALAGATINAAASLGRADTHGSLEVGKFADMVVINAERWEHLIYQIGGHDDIIQHVVKHGKVVF 426
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BLAST of Imidazolonepropionase vs. UniProt/SwissProt
Match: sp|Q7SXK5|HUTI_DANRE (Probable imidazolonepropionase OS=Danio rerio OX=7955 GN=amdhd1 PE=2 SV=2)

HSP 1 Score: 431.024 bits (1107), Expect = 1.079e-147
Identity = 202/387 (52.20%), Postives = 278/387 (71.83%), Query Frame = 2 
Query:  158 SICVDEVGNIKEINETEELIAKY---SYENLVDCKGGSIIPGFVDAHTHPVWAGDRVHEFEMKLAGASYLEIHNAGGGIHFSVDATTKASEISLEMSLKKRLMGMLQHGTTTVECKTGYGLLWETERKMLQVLTNMKKCLPIDISITFLPAHAIPKNSSSWQHTKDIVDNQIPKLKQCLISNELECNNIDVFCEKGIFEIEETKQILEAGKEIGLNINAHADELFPLGGTEMIAKLKAKAVSHLEEISKEGIKSLKEHGTTAVLLPTTAYLLSLKPPPVQDMIKRGVRCALGSDFNPNAFCLSMPIVMNLACVLYKMSMNEALLGATINGAYALGMEHRVGSLEIGKQADFLVLNETNWQHIIYQFGQSRDIIKFVVKKGNIVLFNN 1309
            S+ +   G IK +   + +  ++    ++N++D  G  ++PG VDAHTHPVWAGDRVHEF MKLAGA+Y+E+H AGGGIHF+V  T  ASE  L  +LK RL  M++ GTT VECK+GYGL  + E KML+V+ + +K LPI IS T+  AHA+PK  +  + TKDIV  Q+PK+K    S +L+ +NIDVFCEKG+F++  T+ IL+AGK++GLNIN H DEL P+    + A+L A A+SHLEE++ +GI ++ +  T+AVLLPTTAY+L L PP  +DM+  GV  ALGSDFNPNA+C SMP+VM+LACV+ KMSM EAL  +TIN AYAL      GSLE+GKQ D +++N   W+H++YQFG  +++I++V+ KG+ V  N+
Sbjct:   42 SVLIGHDGLIKAVGPADVIETQFEGAKFDNVLDASGMCVLPGLVDAHTHPVWAGDRVHEFAMKLAGATYMEVHEAGGGIHFTVAHTRSASEQHLLAALKSRLERMMRAGTTLVECKSGYGLELDIEVKMLRVINSARKSLPIGISATYCGAHAVPKGKTMEEATKDIVAVQLPKIKHLSASGDLQVDNIDVFCEKGVFDLTSTRCILQAGKDMGLNINFHGDELHPMNSAHLGAELGALAISHLEEVTDDGIVAMAKSKTSAVLLPTTAYILRLTPPRARDMLDAGVIVALGSDFNPNAYCFSMPMVMHLACVMMKMSMPEALAASTINAAYALNRSQTHGSLEVGKQGDLVIINAPRWEHLVYQFGGHQELIRYVIIKGDFVYEND 428
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BLAST of Imidazolonepropionase vs. UniProt/SwissProt
Match: sp|Q68EP2|HUTI_XENTR (Probable imidazolonepropionase OS=Xenopus tropicalis OX=8364 GN=amdhd1 PE=2 SV=1)

HSP 1 Score: 426.017 bits (1094), Expect = 8.682e-146
Identity = 223/419 (53.22%), Postives = 297/419 (70.88%), Query Frame = 2 
Query:   77 LFHNVSQIVT-CSKFDLGILNEKTSG-----KLSICVDEVGNIKEINETEELIAKYS---YENLVDCKGGSIIPGFVDAHTHPVWAGDRVHEFEMKLAGASYLEIHNAGGGIHFSVDATTKASEISLEMSLKKRLMGMLQHGTTTVECKTGYGLLWETERKMLQVLTNMKKCLPIDISITFLPAHAIPKNSSSWQHTKDIVDNQIPKLKQCLISNELECNNIDVFCEKGIFEIEETKQILEAGKEIGLNINAHADELFPLGGTEMIAKLKAKAVSHLEEISKEGIKSLKEHGTTAVLLPTTAYLLSLKPPPVQDMIKRGVRCALGSDFNPNAFCLSMPIVMNLACVLYKMSMNEALLGATINGAYALGMEHRVGSLEIGKQADFLVLNETNWQHIIYQFGQSRDIIKFVVKKGNIVLFN 1306
            L  N  QIV  CSK +  +L +         K S+ +   G IK++   E +  ++S   +EN++DC G  ++PGFVDAHTHPVWAGDRVHEF MKLAGA+Y++IH AGGGI+++V+ TT ASE  L  S K RL  ML+ GTT VECK+GYGL  ETE KML+V+    + L I +S T+  AH++PK  S+ + T DI+ N +P LKQ  ++ E+  +NIDVFCEKG+F+++ T++IL+AGK IGLN+N H DEL P+   E+ A+L A AVSHLEE+S +GI +L +   +AVLLPTTAY+L LK P  +DM+K GV  +LGSDFNPNA+C SMP+VM+LACV  KMS+ EAL  ATIN AYALG  H  GSLE+GKQ D +V+N + W+H+IYQFG  +++I++VV KG IV  N
Sbjct:    8 LLENAEQIVVVCSKEEEYLLEDGMQHLAILEKASLVIGNDGFIKDVGPAETIRNQFSNASFENIIDCSGKCVLPGFVDAHTHPVWAGDRVHEFAMKLAGATYMDIHKAGGGINYTVEHTTTASEEELFCSFKHRLERMLRAGTTLVECKSGYGLKLETELKMLRVIERAHQELDIAVSSTYCGAHSVPKGKSAQEATDDIIANHLPALKQMALNGEIHVDNIDVFCEKGVFDLDSTRKILQAGKAIGLNLNFHGDELNPMNSAELGAELGAHAVSHLEEVSDKGIAALAKAKCSAVLLPTTAYILRLKQPRARDMLKAGVIVSLGSDFNPNAYCFSMPMVMHLACVNMKMSLKEALAAATINAAYALGRAHTHGSLEVGKQGDVVVINASRWEHVIYQFGGHQELIEYVVIKGKIVYKN 426
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BLAST of Imidazolonepropionase vs. UniProt/SwissProt
Match: sp|Q561L6|HUTI_XENLA (Probable imidazolonepropionase OS=Xenopus laevis OX=8355 GN=amdhd1 PE=2 SV=1)

HSP 1 Score: 416.387 bits (1069), Expect = 7.094e-142
Identity = 221/419 (52.74%), Postives = 291/419 (69.45%), Query Frame = 2 
Query:   77 LFHNVSQIVT-CSKFDLGILNEKTSG-----KLSICVDEVGNIKEINETEEL---IAKYSYENLVDCKGGSIIPGFVDAHTHPVWAGDRVHEFEMKLAGASYLEIHNAGGGIHFSVDATTKASEISLEMSLKKRLMGMLQHGTTTVECKTGYGLLWETERKMLQVLTNMKKCLPIDISITFLPAHAIPKNSSSWQHTKDIVDNQIPKLKQCLISNELECNNIDVFCEKGIFEIEETKQILEAGKEIGLNINAHADELFPLGGTEMIAKLKAKAVSHLEEISKEGIKSLKEHGTTAVLLPTTAYLLSLKPPPVQDMIKRGVRCALGSDFNPNAFCLSMPIVMNLACVLYKMSMNEALLGATINGAYALGMEHRVGSLEIGKQADFLVLNETNWQHIIYQFGQSRDIIKFVVKKGNIVLFN 1306
            L  N  QIV  C+K +  +L +         K S+ +   G IK +   E +    +  S+EN++DC G  I+PGFVDAH HPVWAGDRVHEF MKLAGA+Y++IH AGGGI+++V+ TT AS   L  S K RL  ML+ GTT VECK+GYGL  ETE KML+V+    + L I +S T+  AH++PK  S+ +   DI++N +P LKQ  ++ E+  +NIDVFCEKG+F++E T +IL+AGK IGLN+N H DEL P+   E+ A+L A AVSHLEE+S +GI +L +   +AVLLPTTAY+L LK P  +DM+K GV  +LGSDFNPNA+C SMP+VM+LACV  KMS+ EAL  ATIN AYALG  H  GSLE+GKQ D +V+N + W+H+IYQFG  +++I+ VV KG IV  N
Sbjct:    8 LLENAEQIVVVCTKEEQYLLEDGMQHLAVLEKSSLVIGNDGCIKAVGPAETIRNHFSNASFENIIDCSGKCILPGFVDAHIHPVWAGDRVHEFAMKLAGATYMDIHQAGGGINYTVEHTTAASVEELFCSFKHRLERMLRAGTTLVECKSGYGLKLETELKMLRVIERAHRELDIAVSSTYCGAHSVPKGKSAQEAADDIINNHLPALKQMSLNGEIHVDNIDVFCEKGVFDLESTGRILQAGKAIGLNLNFHGDELNPMNSAELGAELGAHAVSHLEEVSDKGIAALAKAKCSAVLLPTTAYILRLKQPRARDMLKAGVIVSLGSDFNPNAYCFSMPMVMHLACVNMKMSLKEALAAATINAAYALGRAHTHGSLEVGKQGDVVVINASRWEHVIYQFGGHQELIECVVIKGKIVYKN 426
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BLAST of Imidazolonepropionase vs. UniProt/SwissProt
Match: sp|Q96NU7|HUTI_HUMAN (Probable imidazolonepropionase OS=Homo sapiens OX=9606 GN=AMDHD1 PE=1 SV=2)

HSP 1 Score: 410.609 bits (1054), Expect = 9.825e-140
Identity = 202/383 (52.74%), Postives = 280/383 (73.11%), Query Frame = 2 
Query:  158 SICVDEVGNIKEINETEELIAKYS---YENLVDCKGGSIIPGFVDAHTHPVWAGDRVHEFEMKLAGASYLEIHNAGGGIHFSVDATTKASEISLEMSLKKRLMGMLQHGTTTVECKTGYGLLWETERKMLQVLTNMKKCLPIDISITFLPAHAIPKNSSSWQHTKDIVDNQIPKLKQCLISNELECNNIDVFCEKGIFEIEETKQILEAGKEIGLNINAHADELFPLGGTEMIAKLKAKAVSHLEEISKEGIKSLKEHGTTAVLLPTTAYLLSLKPPPVQDMIKRGVRCALGSDFNPNAFCLSMPIVMNLACVLYKMSMNEALLGATINGAYALGMEHRVGSLEIGKQADFLVLNETNWQHIIYQFGQSRDIIKFVVKKGNIV 1297
            S+ V + G IK I   + +  ++S   +E ++DC G  I+PG VDAHTHPVWAG+RVHEF MKLAGA+Y+EIH AGGGIHF+V+ T +A+E  L  SL++RL  M++ GTT VECK+GYGL  ETE KML+V+   ++ L I IS T+  AH++PK  ++ +   DI++N +PKLK+   + E+  +NIDVFCEKG+F+++ T++IL+ GK+IGL IN H DEL P+   E+ A+L A+A+SHLEE+S EGI ++     +A+LLPTTAY+L LK P  + M+  GV  ALGSDFNPNA+C SMP+VM+LACV  +MSM EAL  ATIN AYALG  H  GSLE+GKQ D +++N + W+H+IYQFG   ++I++V+ KG ++
Sbjct:   41 SLVVGKDGFIKAIGPADVIQRQFSGETFEEIIDCSGKCILPGLVDAHTHPVWAGERVHEFAMKLAGATYMEIHQAGGGIHFTVERTRQATEEELFRSLQQRLQCMMRAGTTLVECKSGYGLDLETELKMLRVIERARRELDIGISATYCGAHSVPKGKTATEAADDIINNHLPKLKELGRNGEIHVDNIDVFCEKGVFDLDSTRRILQRGKDIGLQINFHGDELHPMKAAELGAELGAQAISHLEEVSDEGIVAMATARCSAILLPTTAYMLRLKQPRARKMLDEGVIVALGSDFNPNAYCFSMPMVMHLACVNMRMSMPEALAAATINAAYALGKSHTHGSLEVGKQGDLIIINSSRWEHLIYQFGGHHELIEYVIAKGKLI 423
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BLAST of Imidazolonepropionase vs. TrEMBL
Match: A0A0L8G4J1 (Amidohydro-rel domain-containing protein OS=Octopus bimaculoides OX=37653 GN=OCBIM_22000529mg PE=4 SV=1)

HSP 1 Score: 444.891 bits (1143), Expect = 1.472e-150
Identity = 217/396 (54.80%), Postives = 293/396 (73.99%), Query Frame = 2 
Query:  122 LGILNEKTSGKLSICVDEVGNIKEINETEELIAKY---SYENLVDCKGGSIIPGFVDAHTHPVWAGDRVHEFEMKLAGASYLEIHNAGGGIHFSVDATTKASEISLEMSLKKRLMGMLQHGTTTVECKTGYGLLWETERKMLQVLTNMKKCLPIDISITFLPAHAIPKNSSSWQHTKDIVDNQIPKLKQCLISNELECNNIDVFCEKGIFEIEETKQILEAGKEIGLNINAHADELFPLGGTEMIAKLKAKAVSHLEEISKEGIKSLKEHGTTAVLLPTTAYLLSLKPPPVQDMIKRGVRCALGSDFNPNAFCLSMPIVMNLACVLYKMSMNEALLGATINGAYALGMEHRVGSLEIGKQADFLVLNETNWQHIIYQFGQSRDIIKFVVKKGNIVL 1300
            L +LN K +  LS+ VD +GNI EI +T+E++ KY    ++ ++D KG  I+PGFVDAHTHPVWAGDRVHEF MKL+GASY+E+H AGGGIHF+V+ T KASE  L  SLK+RL  MLQ GTT VECK+GYGL   TE KML V+   KK +PIDIS TF  AHA+PK+ ++ + T D+++NQ+ ++K+ + S +L  +NIDVFCEK +F+I +++ ILEAG++ GL IN H DEL PL G EM A+L A A+SHLEEIS EG++++ + G+  V+LPTTAY+L LKPP V  MI  G+  ALGSDFNPNA+CLSMP+VM+LA V  +MS+ ++L+ +TIN A ALG     GSL  GK A+ +++  + W+H+IYQ G   D+IK+V+  GN+V+
Sbjct:   36 LQVLNAKDNDSLSLVVDRIGNILEIGDTKEILLKYPVSQFKKVIDVKGMCILPGFVDAHTHPVWAGDRVHEFAMKLSGASYMEVHQAGGGIHFTVEHTQKASEDELLESLKERLWQMLQAGTTLVECKSGYGLNTNTEVKMLTVIERAKKEVPIDISSTFCGAHAVPKDKTAEEATYDVINNQLVRVKELMDSRKLHVDNIDVFCEKFVFDINQSRAILEAGQKCGLAINFHGDELNPLKGAEMGAQLGALAISHLEEISDEGMQAMAKAGSVGVILPTTAYILRLKPPNVVKMINTGMAIALGSDFNPNAYCLSMPLVMHLASVNLRMSLQQSLVASTINAAKALGKSTTHGSLVPGKVANLVLIEASRWEHLIYQMGCYTDLIKYVIVHGNVVV 431
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BLAST of Imidazolonepropionase vs. TrEMBL
Match: R7UIN2 (Amidohydro-rel domain-containing protein OS=Capitella teleta OX=283909 GN=CAPTEDRAFT_166960 PE=4 SV=1)

HSP 1 Score: 442.58 bits (1137), Expect = 7.374e-150
Identity = 211/389 (54.24%), Postives = 281/389 (72.24%), Query Frame = 2 
Query:  158 SICVDEVGNIKEINETEELIAKY---SYENLVDCKGGSIIPGFVDAHTHPVWAGDRVHEFEMKLAGASYLEIHNAGGGIHFSVDATTKASEISLEMSLKKRLMGMLQHGTTTVECKTGYGLLWETERKMLQVLTNMKKC--LPIDISITFLPAHAIPKNSSSWQHTKDIVDNQIPKLKQCLISNELECNNIDVFCEKGIFEIEETKQILEAGKEIGLNINAHADELFPLGGTEMIAKLKAKAVSHLEEISKEGIKSLKEHGTTAVLLPTTAYLLSLKPPPVQDMIKRGVRCALGSDFNPNAFCLSMPIVMNLACVLYKMSMNEALLGATINGAYALGMEHRVGSLEIGKQADFLVLNETNWQHIIYQFGQSRDIIKFVVKKGNIVLFNN 1309
            SI VD  G I ++   +E+ AKY    +E  +D  G S+IPGFVD HTHPVW GDRVHEF MKLAGA+Y+E+H AGGGI F+VD   +AS   L  SLK+  M ML+ G+T  E K+GYGL  E E KMLQV+  + K   +P+ +S+T+  AHA+PK S++ + T+D++ NQ+P++K  + S +L  +NIDVFCE+G+F++++TK+ILEAG E GL IN H +EL  L   EM A++KA+A+SHLEEIS EGI ++ + G+  V+LPTTAY+L L PPPV+ MI+ G+  ALGSDFNPNA C SMP+V++LACV   MSMNEAL+ AT+N A +LG   R+GSLE+GKQAD LVLN   W+HI+YQFG   D+I+ V+K G IV  N 
Sbjct:   44 SIIVDHKGKIVDLGRDDEICAKYKKEQFEKTLDATGCSVIPGFVDGHTHPVWVGDRVHEFAMKLAGATYMEVHRAGGGIMFTVDRVRRASVDELYTSLKQYAMKMLRCGSTFAEMKSGYGLDAENEIKMLQVINRLIKDEEVPLGVSVTYCGAHAVPKGSTAAEATEDVISNQLPQIKALMDSGDLNVDNIDVFCEQGVFDVDQTKRILEAGVEAGLAINFHGEELHQLNSAEMGAEMKARAISHLEEISDEGITAMAKSGSVGVVLPTTAYILRLSPPPVRKMIEGGMAVALGSDFNPNAHCFSMPLVVHLACVTMHMSMNEALVAATLNAASSLGQSDRIGSLEVGKQADLLVLNSARWEHIVYQFGSHADVIREVIKDGKIVHTNQ 432
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BLAST of Imidazolonepropionase vs. TrEMBL
Match: K1R7V5 (Putative imidazolonepropionase OS=Crassostrea gigas OX=29159 GN=CGI_10020621 PE=4 SV=1)

HSP 1 Score: 441.81 bits (1135), Expect = 2.186e-149
Identity = 211/394 (53.55%), Postives = 284/394 (72.08%), Query Frame = 2 
Query:  128 ILNEKTSGKLSICVDEVGNIKEINETEELIAKYSY-----ENLVDCKGGSIIPGFVDAHTHPVWAGDRVHEFEMKLAGASYLEIHNAGGGIHFSVDATTKASEISLEMSLKKRLMGMLQHGTTTVECKTGYGLLWETERKMLQVLTNMKKCLPIDISITFLPAHAIPKNSSSWQHTKDIVDNQIPKLKQCLISNELECNNIDVFCEKGIFEIEETKQILEAGKEIGLNINAHADELFPLGGTEMIAKLKAKAVSHLEEISKEGIKSLKEHGTTAVLLPTTAYLLSLKPPPVQDMIKRGVRCALGSDFNPNAFCLSMPIVMNLACVLYKMSMNEALLGATINGAYALGMEHRVGSLEIGKQADFLVLNETNWQHIIYQFGQSRDIIKFVVKKGNI 1294
            I+  K    +SI VD  G I+ I    E ++KY       E +++ +G  I+PG VDAHTHPVW GDRVHEF MKLAGASY+E+H AGGGIHF+V+ T KAS+  L +S  KRL  M+  GTT VECK+GYGL  ETE KML+V+   K+  P+ IS TF  AHAIPK S++ + T+D+++NQ+P +K+ +   +L  +NIDVFCEKG+F++E+++ ILEAGK  GL IN H DEL PL G +M A+L A A+SHLEEIS+EGI ++   G+  V+LPTTAY+L L+PPPV+ M++ GV  ALGSDFNPNA+C++MP VM+LACVL +M+M E+L+ AT+N A ALG+    GSL  GK AD ++++   W+H+IYQFG    II +V+KKG+I
Sbjct:   36 IIKAKGEDGVSILVDSNGRIEFIGLDSERVSKYPRSEDEAEQVIEAEGKCIVPGLVDAHTHPVWVGDRVHEFAMKLAGASYMEVHEAGGGIHFTVENTRKASQDELYVSFSKRLYDMMSAGTTCVECKSGYGLDTETEIKMLKVIETAKREHPLTISSTFCGAHAIPKGSTAEKATEDVINNQLPAIKRLMKEGQLHVDNIDVFCEKGVFDLEQSRAILEAGKAAGLQINFHGDELHPLNGAKMGAELGALAISHLEEISEEGIAAMASSGSVGVVLPTTAYILRLRPPPVRRMLEAGVAVALGSDFNPNAYCMAMPTVMHLACVLLRMTMPESLIAATLNAASALGLSKDYGSLSRGKYADLVIIDAPRWEHLIYQFGCHDKIIDYVIKKGHI 429
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BLAST of Imidazolonepropionase vs. TrEMBL
Match: A0A090XD42 (Putative atrazine chlorohydrolase/guanine deaminase (Fragment) OS=Ixodes ricinus OX=34613 PE=2 SV=1)

HSP 1 Score: 441.039 bits (1133), Expect = 2.840e-149
Identity = 222/423 (52.48%), Postives = 293/423 (69.27%), Query Frame = 2 
Query:   62 QIMYKLFHNVSQIVT----CSKFD----LGILNEKTSGKLSICVDEVGNIKEINET---EELIAKYSYENLVDCKGGSIIPGFVDAHTHPVWAGDRVHEFEMKLAGASYLEIHNAGGGIHFSVDATTKASEISLEMSLKKRLMGMLQHGTTTVECKTGYGLLWETERKMLQVLTNMKKCLPIDISITFLPAHAIPKNSSSWQHTKDIVDNQIPKLKQCLISNELECNNIDVFCEKGIFEIEETKQILEAGKEIGLNINAHADELFPLGGTEMIAKLKAKAVSHLEEISKEGIKSLKEHGTTAVLLPTTAYLLSLKPPPVQDMIKRGVRCALGSDFNPNAFCLSMPIVMNLACVLYKMSMNEALLGATINGAYALGMEHRVGSLEIGKQADFLVLNETNWQHIIYQFGQSRDIIKFVVKKGNIV 1297
            +++ K    V Q+V     C K D    L IL    S   S+ VD+ G I  I+E+   EE  +   +EN+VD  G  +IPG VD+HTHPVWAGDRVHEF MKLAGASYLEIH  GGGIHF+VD T  AS  SL  SL  RL  ML+ GTT VE K+GYGL  E+E K+L+V+   +   PIDIS T+   HA+P+  +  + T+DIV  QIP++K+ ++   L   NIDVFCE+G+F+++ T+ IL+AG+ +GL IN H+DEL  +GGTEM A LKA+A+SHLE +S EG++++ E GTTAV+LPTTA+LL L+ PPV+D+I+ GV  ALGSDFNPNA+C SMP+VM LAC++  MS+ EAL  +TINGA ALG     GS+E+GK AD +V+   +W+H+IYQFG     IK V+K GN+V
Sbjct:    2 RLLLKNARQVVQVVNNGEKCLKGDSMKKLAILEGTDSHGFSLVVDQFGMIAAIDESGTIEENFSGCQFENVVDATGCCVIPGLVDSHTHPVWAGDRVHEFAMKLAGASYLEIHAQGGGIHFTVDHTKDASAESLLDSLVDRLGCMLRSGTTLVEAKSGYGLDLESEVKLLRVIDEARARTPIDISSTYCGGHAVPRGKTMGEATEDIVRKQIPEIKRRMLEGTLNVENIDVFCEEGVFDVDSTRSILQAGRSLGLRINFHSDELSCIGGTEMGASLKAEAISHLERVSPEGVRAMAEAGTTAVILPTTAFLLRLESPPVRDLIQAGVAVALGSDFNPNAYCTSMPMVMYLACIICHMSLEEALAASTINGAAALGRSRTHGSIEVGKMADLVVVEAPSWEHLIYQFGCHDRTIKCVIKAGNVV 424
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BLAST of Imidazolonepropionase vs. TrEMBL
Match: C1C0P6 (Probable imidazolonepropionase OS=Caligus clemensi OX=344056 GN=HUTI PE=2 SV=1)

HSP 1 Score: 440.654 bits (1132), Expect = 4.594e-149
Identity = 210/385 (54.55%), Postives = 281/385 (72.99%), Query Frame = 2 
Query:  155 LSICVDEVGNIKEINETEELIAKYS----YENLVDCKGGSIIPGFVDAHTHPVWAGDRVHEFEMKLAGASYLEIHNAGGGIHFSVDATTKASEISLEMSLKKRLMGMLQHGTTTVECKTGYGLLWETERKMLQVLTNMKKCLPIDISITFLPAHAIPKNSSSWQHTKDIVDNQIPKLKQCLISNELECNNIDVFCEKGIFEIEETKQILEAGKEIGLNINAHADELFPLGGTEMIAKLKAKAVSHLEEISKEGIKSLKEHGTTAVLLPTTAYLLSLKPPPVQDMIKRGVRCALGSDFNPNAFCLSMPIVMNLACVLYKMSMNEALLGATINGAYALGMEHRVGSLEIGKQADFLVLNETNWQHIIYQFGQSRDIIKFVVKKGNIV 1297
            +S+ VDE G I+ I    ++   Y     +E ++  +G  ++PG +D HTHPVWAGDRVHEF MKLAGA+Y+E+H AGGGI+F+VD T  ASE  L  S  KRL  ML+ GTTTVECK+GYGL  ETE KML+V+ N +K +PI+IS T+  AH++PK +++ + T DI+ +QIP++ +  +S  L   N DVFCEKG+F +E++K+ILEAG++ GL IN H DEL PLGG EM A + A+A+SHLEE+S +GIK +    T AV+LPTTAY+L LK PPV++MI+ GV  ALGSDFNPNAFCLSM +VM+LACV  +MS+ EA++ +T+N AY+L      GSLE GK+ADFL++N   W+H+IYQFG   DII+ V+K G IV
Sbjct:   43 VSLVVDEHGKIEMIGRDSDIRKAYPDKSIFERVISAEGKCLVPGLIDGHTHPVWAGDRVHEFAMKLAGATYMEVHEAGGGINFTVDHTRNASEEDLTDSFSKRLHRMLRAGTTTVECKSGYGLNLETELKMLRVIENGRKKVPIEISSTYCGAHSVPKGTTAEEATSDIISHQIPRIIKENMSGTLSVENTDVFCEKGVFNVEQSKRILEAGQQKGLTINFHGDELNPLGGAEMGASISARAISHLEEVSGQGIKDMAASSTAAVILPTTAYMLRLKNPPVREMIEAGVIVALGSDFNPNAFCLSMSMVMHLACVDQRMSLEEAIVASTLNSAYSLNRSSTHGSLEPGKEADFLIVNAPKWEHLIYQFGGHSDIIEHVIKTGTIV 427
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BLAST of Imidazolonepropionase vs. Ensembl Cavefish
Match: si:ch73-71d17.1 (amidohydrolase domain containing 1 [Source:NCBI gene;Acc:103043752])

HSP 1 Score: 397.512 bits (1020), Expect = 1.386e-135
Identity = 199/387 (51.42%), Postives = 275/387 (71.06%), Query Frame = 2 
Query:  158 SICVDEVGNIKEINETEELIAKYS---YENLVDCKGGSIIPGFVDAHTHPVWAGDRVHEFEMKLAGASYLEIHNAGGGIHFSVDATTKASEISLEMSLKKRLMGMLQHGTTTVECKTGYGLLWETERKMLQVLTNMKKCLPIDISITFLPAHAIPKNSSSWQHTKDIVDNQIPKLKQCLISNELECNNIDVFCEKGIFEIEETKQILEAGKEIGLNINAHADELFPLGGTEMIAKLKAKAVSHLEEISKEGIKSLKEHGTTAVLLPTTAYLLSLKPPPVQDMIKRGVRCALGSDFNPNAFCLSMPIVMNLACVLYKMSMNEALLGATINGAYALGMEHRVGSLEIGKQADFLVLNETNWQHIIYQFGQSRDIIKFVVKKGNIVLFNN 1309
            S+ +   G IK +   + + +++    ++ ++D  G  ++PG VDAHTHPVWAGDRVHEF MKLAGA+Y+E+H AGGGIHF+V  T  A   +L   LK RL  ML+ GTT VECK+GYGL  ETE KML V+ + +K  PI IS T+  AHA+P+  +  Q T+DI+  Q+P +++ + +  L+ +NIDVFCEKG+F++  T++IL+AGK++GLNIN H DEL P+   ++ A+L A A+SHLEE++ EGI ++    T+AVLLPTTAY+L L  P  +DM+  GV  +LGSDFNPNA+C SMP+VM+LACV  KMS++EAL  ATIN AYAL   H  GS+E GKQ D L++N   W+H+IYQFG  +++I+ V+ KGNIV  N+
Sbjct:   40 SVVIGHDGLIKAVGPADSIESQFRRAVFDKVLDATGMCVLPGLVDAHTHPVWAGDRVHEFAMKLAGATYMEVHEAGGGIHFTVRHTHAADSETLLQGLKGRLERMLRAGTTLVECKSGYGLELETELKMLSVIDSARKSSPIGISSTYCGAHAVPRGKTMEQATEDILAVQLPAIQKHISAGSLQVDNIDVFCEKGVFDLNSTRRILQAGKDMGLNINFHGDELHPMNSAQLGAELGALAISHLEEVTDEGIAAMAASQTSAVLLPTTAYILRLPCPRARDMLDAGVIVSLGSDFNPNAYCCSMPMVMHLACVTLKMSLSEALAAATINAAYALNCSHTHGSVEPGKQGDLLIINAPRWEHLIYQFGSHQELIRSVIIKGNIVYEND 426
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BLAST of Imidazolonepropionase vs. Ensembl Nematostella
Match: AMDHD1 (Probable imidazolonepropionase [Source:UniProtKB/Swiss-Prot;Acc:A7RX26])

HSP 1 Score: 433.721 bits (1114), Expect = 3.404e-150
Identity = 213/397 (53.65%), Postives = 281/397 (70.78%), Query Frame = 2 
Query:  119 DLGILNEKTSGKLSICVDEVGNIKEINETEELIAKY---SYENLVDCKGGSIIPGFVDAHTHPVWAGDRVHEFEMKLAGASYLEIHNAGGGIHFSVDATTKASEISLEMSLKKRLMGMLQHGTTTVECKTGYGLLWETERKMLQVLTNMKKCLPIDISITFLPAHAIPKNSSSWQHTKDIVDNQIPKLKQCLISNELECNNIDVFCEKGIFEIEETKQILEAGKEIGLNINAHADELFPLGGTEMIAKLKAKAVSHLEEISKEGIKSLKEHGTTAVLLPTTAYLLSLKPPPVQDMIKRGVRCALGSDFNPNAFCLSMPIVMNLACVLYKMSMNEALLGATINGAYALGMEHRVGSLEIGKQADFLVLNETNWQHIIYQFGQSRDIIKFVVKKGNIVL 1300
            ++ IL    +  +S+  DE G I+ I   +++  +Y   S+ + +D  G  ++PG +D HTHPVW GDRVHEF MKLAGASY+++H AGGGI+F+V+   KA+E  L   LK+RL  MLQ GTT VE K+GYGL  E E KML+V+   KK LPI+IS TF  AHAIP+ S++ Q   +I++ QIP L + + + EL+  NIDVFCEKG+FE+EET+ IL+AGK+ GL IN H DEL P+ G E+ A+L A+A+SHLEEIS+EGIK++ +     VLLPTTAY+L LKPPP + MI  GV  ALG+DFNPNA+CLSMP+ M+LAC + +MSM EAL GATIN A +LG     GSLE+GK AD +V+N   W+H+IYQ G   DII+ VVK G +V 
Sbjct:   30 NIAILEGSVNRGISVVADEFGKIECIGYDDDVEPQYNQCSFASEIDATGMCVLPGLIDGHTHPVWVGDRVHEFAMKLAGASYMDVHKAGGGINFTVEHVHKATEDELYEPLKQRLNRMLQCGTTLVEAKSGYGLNTENEMKMLKVIERAKKELPIEISSTFCGAHAIPRGSTAKQAADNIINEQIPTLVKAIKAGELDVENIDVFCEKGVFEVEETRVILQAGKDAGLAINFHGDELHPIKGAELGAELGARAISHLEEISEEGIKAMSKSSVIGVLLPTTAYILRLKPPPARAMIDAGVAIALGTDFNPNAYCLSMPLTMHLACCILRMSMTEALAGATINAAASLGRADTHGSLEVGKFADMVVINAERWEHLIYQIGGHDDIIQHVVKHGKVVF 426
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BLAST of Imidazolonepropionase vs. Ensembl Nematostella
Match: EDO26808 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7TB08])

HSP 1 Score: 82.8037 bits (203), Expect = 3.486e-19
Identity = 43/96 (44.79%), Postives = 58/96 (60.42%), Query Frame = 2 
Query:  239 LVDCKGGSIIPGFVDAHTHPVWAGDRVHEFEMKLAGASYLEIHNAGGGIHFSVDATTKASEISLEMSLKKRLMGMLQHGTTTVECKTGYGLLWETE 526
            ++D KG  I+P +VD+HTH V+AG+R+ EF  ++ G SY EI N GGGI  S     + SE  +    K RL  ++  GT  VE K+GYGL  E E
Sbjct:   36 IIDAKGKVILPTWVDSHTHIVYAGNRIQEFVDRINGLSYEEIANRGGGILNSAKKLNETSEEEIYEQSKLRLEEVMHQGTGAVEIKSGYGLTVEGE 131
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BLAST of Imidazolonepropionase vs. Ensembl Nematostella
Match: EDO32834 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7STY5])

HSP 1 Score: 46.595 bits (109), Expect = 6.625e-6
Identity = 20/42 (47.62%), Postives = 31/42 (73.81%), Query Frame = 2 
Query: 1091 YKMSMNEALLGATINGAYALGMEHRVGSLEIGKQADFLVLNE 1216
            YK +++EAL   TIN A+ L  E  +GSLE+GK+AD L++++
Sbjct:  137 YKATLDEALKAYTINAAWQLRKEKELGSLEVGKKADLLIISD 178
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BLAST of Imidazolonepropionase vs. Ensembl Medaka
Match: si:ch73-71d17.1 (amidohydrolase domain containing 1 [Source:NCBI gene;Acc:101169652])

HSP 1 Score: 407.527 bits (1046), Expect = 1.927e-139
Identity = 210/420 (50.00%), Postives = 287/420 (68.33%), Query Frame = 2 
Query:   77 LFHNVSQIVTCSKFDLGILNEKTSGKLSI------CVDEVGNIKEINETEELIAKY---SYENLVDCKGGSIIPGFVDAHTHPVWAGDRVHEFEMKLAGASYLEIHNAGGGIHFSVDATTKASEISLEMSLKKRLMGMLQHGTTTVECKTGYGLLWETERKMLQVLTNMKKCLPIDISITFLPAHAIPKNSSSWQHTKDIVDNQIPKLKQCLISNELECNNIDVFCEKGIFEIEETKQILEAGKEIGLNINAHADELFPLGGTEMIAKLKAKAVSHLEEISKEGIKSLKEHGTTAVLLPTTAYLLSLKPPPVQDMIKRGVRCALGSDFNPNAFCLSMPIVMNLACVLYKMSMNEALLGATINGAYALGMEHRVGSLEIGKQADFLVLNETNWQHIIYQFGQSRDIIKFVVKKGNIVLFNN 1309
            L  N  Q+V   +     LN+     LS+       +   G IK +   E + A+Y   S ++++D     ++PG VDAHTHPVWAGDRVHEF MKLAGASY+++H AGGGIHF+V+ T  A+   L  +L +RL  ML+ GTT VECK+GYGL  +TE KML+V+   ++ LPI+IS T+  AHA+PK  +  + T D++  Q+P+LK+ + +  L+ +NIDVFCE+G+F +  T +IL+AG+++GLNIN H DEL P+   ++ A+L A A+SHLEE++ EGI ++    T A+LLPTTAY+L L  P  +DM+  GV  ALGSDFNPNAFC SMPIVM+LACV  +MSM+EAL  ATIN AYALG  H  GSLE+ K  D LVLN + W+H+IYQ G  ++I+++VV KGNIV  N+
Sbjct:    8 LVKNAKQVVLICRNGEKFLNKDGMKSLSVIENGSVVIGRDGLIKAVGPAETISAQYPESSCDHVIDATDMCVLPGLVDAHTHPVWAGDRVHEFAMKLAGASYMDVHRAGGGIHFTVEHTRAAAASELLDALTRRLQRMLRAGTTLVECKSGYGLELQTEVKMLEVIEAARRSLPINISSTYCGAHAVPKGRTEAEATADVLQVQLPRLKELMSAGTLQVDNIDVFCERGVFGLSSTHRILQAGRDMGLNINFHGDELHPMNSAQLGAELGALAISHLEEVTDEGIVAMATAKTAAILLPTTAYILRLPQPRARDMLDAGVIVALGSDFNPNAFCCSMPIVMHLACVNMRMSMSEALAAATINAAYALGRAHTHGSLEVSKHGDLLVLNCSRWEHLIYQLGGHQEILRYVVIKGNIVHDND 427
[Close]
BLAST of Imidazolonepropionase vs. Ensembl Medaka
Match: si:ch73-71d17.1 (amidohydrolase domain containing 1 [Source:NCBI gene;Acc:101169652])

HSP 1 Score: 365.155 bits (936), Expect = 4.156e-123
Identity = 198/420 (47.14%), Postives = 269/420 (64.05%), Query Frame = 2 
Query:   77 LFHNVSQIVTCSKFDLGILNEKTSGKLSI------CVDEVGNIKEINETEELIAKY---SYENLVDCKGGSIIPGFVDAHTHPVWAGDRVHEFEMKLAGASYLEIHNAGGGIHFSVDATTKASEISLEMSLKKRLMGMLQHGTTTVECKTGYGLLWETERKMLQVLTNMKKCLPIDISITFLPAHAIPKNSSSWQHTKDIVDNQIPKLKQCLISNELECNNIDVFCEKGIFEIEETKQILEAGKEIGLNINAHADELFPLGGTEMIAKLKAKAVSHLEEISKEGIKSLKEHGTTAVLLPTTAYLLSLKPPPVQDMIKRGVRCALGSDFNPNAFCLSMPIVMNLACVLYKMSMNEALLGATINGAYALGMEHRVGSLEIGKQADFLVLNETNWQHIIYQFGQSRDIIKFVVKKGNIVLFNN 1309
            L  N  Q+V   +     LN+     LS+       +   G IK +   E + A+Y   S ++++D     ++PG VDAHTHPVWAGDRVHEF MKLAGASY+++H AGGGIHF+V+ T  A+   L  +L +RL  ML+ GTT VECK+GYGL  +TE KML+V+   ++ LPI+IS T+  AHA+PK  +  + T D++  Q+P+LK+ +                       +   L+AG+++GLNIN H DEL P+   ++ A+L A A+SHLEE++ EGI ++    T A+LLPTTAY+L L  P  +DM+  GV  ALGSDFNPNAFC SMPIVM+LACV  +MSM+EAL  ATIN AYALG  H  GSLE+ K  D LVLN + W+H+IYQ G  ++I+++VV KGNIV  N+
Sbjct:    8 LVKNAKQVVLICRNGEKFLNKDGMKSLSVIENGSVVIGRDGLIKAVGPAETISAQYPESSCDHVIDATDMCVLPGLVDAHTHPVWAGDRVHEFAMKLAGASYMDVHRAGGGIHFTVEHTRAAAASELLDALTRRLQRMLRAGTTLVECKSGYGLELQTEVKMLEVIEAARRSLPINISSTYCGAHAVPKGRTEAEATADVLQVQLPRLKELM-----------------------SAGTLQAGRDMGLNINFHGDELHPMNSAQLGAELGALAISHLEEVTDEGIVAMATAKTAAILLPTTAYILRLPQPRARDMLDAGVIVALGSDFNPNAFCCSMPIVMHLACVNMRMSMSEALAAATINAAYALGRAHTHGSLEVSKHGDLLVLNCSRWEHLIYQLGGHQEILRYVVIKGNIVHDND 404
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BLAST of Imidazolonepropionase vs. Planmine SMEST
Match: SMESG000058218.1 (SMESG000058218.1)

HSP 1 Score: 849.351 bits (2193), Expect = 0.000e+0
Identity = 412/414 (99.52%), Postives = 412/414 (99.52%), Query Frame = 2 
Query:   68 MYKLFHNVSQIVTCSKFDLGILNEKTSGKLSICVDEVGNIKEINETEELIAKYSYENLVDCKGGSIIPGFVDAHTHPVWAGDRVHEFEMKLAGASYLEIHNAGGGIHFSVDATTKASEISLEMSLKKRLMGMLQHGTTTVECKTGYGLLWETERKMLQVLTNMKKCLPIDISITFLPAHAIPKNSSSWQHTKDIVDNQIPKLKQCLISNELECNNIDVFCEKGIFEIEETKQILEAGKEIGLNINAHADELFPLGGTEMIAKLKAKAVSHLEEISKEGIKSLKEHGTTAVLLPTTAYLLSLKPPPVQDMIKRGVRCALGSDFNPNAFCLSMPIVMNLACVLYKMSMNEALLGATINGAYALGMEHRVGSLEIGKQADFLVLNETNWQHIIYQFGQSRDIIKFVVKKGNIVLFNN 1309
            MYKLFHNVSQIVTCSKFDLGILN KTSGKLSICVDEVGNIKEINETEELIAKYSYENL DCKGGSIIPGFVDAHTHPVWAGDRVHEFEMKLAGASYLEIHNAGGGIHFSVDATTKASEISLEMSLKKRLMGMLQHGTTTVECKTGYGLLWETERKMLQVLTNMKKCLPIDISITFLPAHAIPKNSSSWQHTKDIVDNQIPKLKQCLISNELECNNIDVFCEKGIFEIEETKQILEAGKEIGLNINAHADELFPLGGTEMIAKLKAKAVSHLEEISKEGIKSLKEHGTTAVLLPTTAYLLSLKPPPVQDMIKRGVRCALGSDFNPNAFCLSMPIVMNLACVLYKMSMNEALLGATINGAYALGMEHRVGSLEIGKQADFLVLNETNWQHIIYQFGQSRDIIKFVVKKGNIVLFNN
Sbjct:    1 MYKLFHNVSQIVTCSKFDLGILNGKTSGKLSICVDEVGNIKEINETEELIAKYSYENLFDCKGGSIIPGFVDAHTHPVWAGDRVHEFEMKLAGASYLEIHNAGGGIHFSVDATTKASEISLEMSLKKRLMGMLQHGTTTVECKTGYGLLWETERKMLQVLTNMKKCLPIDISITFLPAHAIPKNSSSWQHTKDIVDNQIPKLKQCLISNELECNNIDVFCEKGIFEIEETKQILEAGKEIGLNINAHADELFPLGGTEMIAKLKAKAVSHLEEISKEGIKSLKEHGTTAVLLPTTAYLLSLKPPPVQDMIKRGVRCALGSDFNPNAFCLSMPIVMNLACVLYKMSMNEALLGATINGAYALGMEHRVGSLEIGKQADFLVLNETNWQHIIYQFGQSRDIIKFVVKKGNIVLFNN 414
The following BLAST results are available for this feature:
BLAST of Imidazolonepropionase vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 1
Match NameE-valueIdentityDescription
AMDHD12.046e-14052.74amidohydrolase domain containing 1 [Source:HGNC Sy... [more]
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BLAST of Imidazolonepropionase vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 1
Match NameE-valueIdentityDescription
T12A2.11.082e-12945.48pep chromosome:WBcel235:III:6251811:6271282:1 gene... [more]
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BLAST of Imidazolonepropionase vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Imidazolonepropionase vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 2
Match NameE-valueIdentityDescription
si:ch73-71d17.18.949e-14952.45si:ch73-71d17.1 [Source:NCBI gene;Acc:402826][more]
AMDHD15.340e-14852.45si:ch73-71d17.1 [Source:NCBI gene;Acc:402826][more]
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BLAST of Imidazolonepropionase vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 2
Match NameE-valueIdentityDescription
amdhd11.639e-14653.22amidohydrolase domain containing 1 [Source:NCBI ge... [more]
amdhd12.199e-14653.22amidohydrolase domain containing 1 [Source:NCBI ge... [more]
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BLAST of Imidazolonepropionase vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 1
Match NameE-valueIdentityDescription
Amdhd12.342e-13450.91amidohydrolase domain containing 1 [Source:MGI Sym... [more]
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BLAST of Imidazolonepropionase vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|A7RX26|HUTI_NEMVE8.304e-14953.65Probable imidazolonepropionase OS=Nematostella vec... [more]
sp|Q7SXK5|HUTI_DANRE1.079e-14752.20Probable imidazolonepropionase OS=Danio rerio OX=7... [more]
sp|Q68EP2|HUTI_XENTR8.682e-14653.22Probable imidazolonepropionase OS=Xenopus tropical... [more]
sp|Q561L6|HUTI_XENLA7.094e-14252.74Probable imidazolonepropionase OS=Xenopus laevis O... [more]
sp|Q96NU7|HUTI_HUMAN9.825e-14052.74Probable imidazolonepropionase OS=Homo sapiens OX=... [more]
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BLAST of Imidazolonepropionase vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A0L8G4J11.472e-15054.80Amidohydro-rel domain-containing protein OS=Octopu... [more]
R7UIN27.374e-15054.24Amidohydro-rel domain-containing protein OS=Capite... [more]
K1R7V52.186e-14953.55Putative imidazolonepropionase OS=Crassostrea giga... [more]
A0A090XD422.840e-14952.48Putative atrazine chlorohydrolase/guanine deaminas... [more]
C1C0P64.594e-14954.55Probable imidazolonepropionase OS=Caligus clemensi... [more]
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BLAST of Imidazolonepropionase vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 1
Match NameE-valueIdentityDescription
si:ch73-71d17.11.386e-13551.42amidohydrolase domain containing 1 [Source:NCBI ge... [more]
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BLAST of Imidazolonepropionase vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Imidazolonepropionase vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Imidazolonepropionase vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 3
Match NameE-valueIdentityDescription
AMDHD13.404e-15053.65Probable imidazolonepropionase [Source:UniProtKB/... [more]
EDO268083.486e-1944.79Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO328346.625e-647.62Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Imidazolonepropionase vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 2
Match NameE-valueIdentityDescription
si:ch73-71d17.11.927e-13950.00amidohydrolase domain containing 1 [Source:NCBI ge... [more]
si:ch73-71d17.14.156e-12347.14amidohydrolase domain containing 1 [Source:NCBI ge... [more]
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BLAST of Imidazolonepropionase vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 1
Match NameE-valueIdentityDescription
SMESG000058218.10.000e+099.52SMESG000058218.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30018167 ID=SMED30018167|Name=Imidazolonepropionase|organism=Schmidtea mediterranea sexual|type=transcript|length=1360bp
TTTATAACCAGTTATTTATTAGCCTCATAGATAGTGCATTTAGCATAACT
TAATTTATTTACAAATTATGTACAAATTGTTTCACAACGTGTCGCAAATA
GTCACTTGTTCAAAATTTGACCTTGGGATTTTAAATGAAAAAACTTCAGG
AAAATTATCAATTTGTGTGGACGAAGTTGGGAATATCAAGGAAATAAATG
AAACCGAAGAGCTTATAGCAAAGTATTCATATGAAAATTTAGTTGATTGC
AAAGGAGGATCTATTATTCCTGGATTTGTCGATGCCCACACCCACCCTGT
ATGGGCTGGTGATAGAGTTCACGAATTCGAAATGAAACTGGCTGGTGCTT
CTTATCTAGAAATTCACAATGCTGGGGGAGGAATTCATTTTTCTGTTGAT
GCAACAACGAAAGCTTCCGAAATTAGTTTAGAAATGTCATTGAAAAAGAG
ATTAATGGGTATGCTGCAGCATGGTACCACGACAGTGGAATGTAAAACTG
GTTATGGTTTGTTATGGGAAACGGAACGTAAAATGTTGCAAGTTTTAACA
AACATGAAAAAATGTCTTCCAATAGATATCTCAATAACATTTTTGCCTGC
TCATGCGATACCAAAAAATTCATCGTCTTGGCAGCATACAAAGGACATTG
TTGATAATCAAATACCGAAATTGAAACAATGTTTAATCTCAAATGAGTTA
GAGTGCAACAATATTGACGTGTTTTGTGAAAAAGGTATTTTTGAAATCGA
AGAAACAAAACAAATTTTAGAAGCAGGTAAAGAAATCGGTTTAAACATAA
ATGCTCATGCAGATGAATTATTTCCACTTGGTGGAACTGAAATGATAGCT
AAATTAAAGGCGAAAGCTGTAAGTCATCTTGAAGAAATATCAAAAGAAGG
AATAAAGTCTTTAAAAGAGCATGGAACCACAGCAGTTCTGCTTCCTACAA
CTGCATATTTATTATCCTTGAAACCTCCTCCAGTACAAGACATGATTAAA
AGAGGTGTCCGGTGTGCTCTGGGATCTGATTTTAACCCTAACGCCTTTTG
TTTATCAATGCCTATTGTCATGAATTTGGCTTGTGTTCTTTATAAAATGT
CAATGAACGAAGCATTGCTGGGCGCAACCATCAATGGTGCATATGCTTTA
GGTATGGAGCATCGGGTCGGTTCTCTGGAAATTGGTAAGCAAGCAGATTT
TCTTGTTTTAAATGAGACCAATTGGCAGCATATTATTTATCAATTCGGTC
AATCTAGGGATATAATCAAGTTTGTGGTTAAAAAAGGAAATATTGTTTTA
TTTAACAATTGAAAGATAGCAGTTTTCAATAATAAATACTTGAACCTTTT
CAAAAAAAAA
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protein sequence of SMED30018167-orf-1

>SMED30018167-orf-1 ID=SMED30018167-orf-1|Name=SMED30018167-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=415bp
MYKLFHNVSQIVTCSKFDLGILNEKTSGKLSICVDEVGNIKEINETEELI
AKYSYENLVDCKGGSIIPGFVDAHTHPVWAGDRVHEFEMKLAGASYLEIH
NAGGGIHFSVDATTKASEISLEMSLKKRLMGMLQHGTTTVECKTGYGLLW
ETERKMLQVLTNMKKCLPIDISITFLPAHAIPKNSSSWQHTKDIVDNQIP
KLKQCLISNELECNNIDVFCEKGIFEIEETKQILEAGKEIGLNINAHADE
LFPLGGTEMIAKLKAKAVSHLEEISKEGIKSLKEHGTTAVLLPTTAYLLS
LKPPPVQDMIKRGVRCALGSDFNPNAFCLSMPIVMNLACVLYKMSMNEAL
LGATINGAYALGMEHRVGSLEIGKQADFLVLNETNWQHIIYQFGQSRDII
KFVVKKGNIVLFNN*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000026gut
PLANA:0002075pigment cell
PLANA:0003116parenchymal cell
Vocabulary: INTERPRO
TermDefinition
IPR005920HutI
IPR011059Metal-dep_hydrolase_composite
IPR006680Amidohydro-rel
IPR032466Metal_Hydrolase
Vocabulary: molecular function
TermDefinition
GO:0016810hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
GO:0016787hydrolase activity
GO:0016812hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
Vocabulary: cellular component
TermDefinition
GO:0005737cytoplasm
Vocabulary: biological process
TermDefinition
GO:0019556histidine catabolic process to glutamate and formamide
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableGENE3DG3DSA:3.20.20.140coord: 69..368
e-value: 1.9E-129
score: 433.6
IPR011059Metal-dependent hydrolase, composite domain superfamilyGENE3DG3DSA:2.30.40.10coord: 6..408
e-value: 1.9E-129
score: 433.6
IPR011059Metal-dependent hydrolase, composite domain superfamilySUPERFAMILYSSF51338Composite domain of metallo-dependent hydrolasescoord: 38..410
IPR005920ImidazolonepropionaseTIGRFAMTIGR01224TIGR01224coord: 30..409
e-value: 8.3E-129
score: 427.6
IPR005920ImidazolonepropionasePANTHERPTHR42752FAMILY NOT NAMEDcoord: 4..410
IPR005920ImidazolonepropionaseCDDcd01296Imidazolone-5PHcoord: 34..407
e-value: 2.56184E-169
score: 476.75
IPR006680Amidohydrolase-relatedPFAMPF01979Amidohydro_1coord: 66..410
e-value: 3.7E-23
score: 82.4
IPR032466Metal-dependent hydrolaseSUPERFAMILYSSF51556Metallo-dependent hydrolasescoord: 68..369