Endo/exonuclease/phosphatase domain-containing protein
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30018103 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 1
Homology
BLAST of Endo/exonuclease/phosphatase domain-containing protein vs. Ensembl Human
Match: PDE12 (phosphodiesterase 12 [Source:HGNC Symbol;Acc:HGNC:25386]) HSP 1 Score: 123.635 bits (309), Expect = 3.324e-29 Identity = 99/396 (25.00%), Postives = 174/396 (43.94%), Query Frame = 2
Query: 266 PIDYCEIFALDIKNQNKICISDLTINDLLISNILIKINEVIYQIYFKPPWIKTCKLPKITMVNIPITPILDLENVNESELSINWYVSKSSSSDD-----------------WIKCHTGT-IFIPSENYLNFFIKLQVNSTLRNK-NQNFQLISTSPIQQYPQM-EYQKLNLFNP-ILSDKTFRICSYNILSHIYAETDKAKSVLYRHCNPEFLTRDYRQCLIFGELLQHKSDIIFLQEVDQSFYQKSLYPILQSYNYEGIFQKKSRTNWEGQAIFWNINKFKLIDNISIPSLSMVINEENSEVYKK-IKRFLRDTNLYNKWQSTGQCMTGCVLETVSLADRKRLMLCNNHLICDPKLEIFRLFQLAVGMLQLEQIKYQYGEVCCDWWRFQCIV*CG 1387
P +CE + + + + D+ D +++I +V Y++ PP +LP+ M P+ P L LE + + WY + + W + ++ PS + +KL + + +L S ++ P + +L+ + D R SYNIL+ YA+T+ +++VLY +C P L DYRQ LI EL + +D+I LQEVD++ + SL P L+++ EG+F+ K EG A F+ +KF L+ I S E+ ++K+ +++ + + K + VL++ + KR+ + N HL PK RL Q+AV + + V CD + ++ CG
Sbjct: 115 PAVFCEPV-VKLYYREEAVAEDVLNVDAWQDGAVLQIGDVKYKVERNPPAFTELQLPRYIMAGFPVCPKLSLEFGDPASSLFRWYKEAKPGAAEPEVGVPSSLSPSSPSSSWTETDVEERVYTPSNADIGLRLKLHCTPGDGQRFGHSRELESVCVVEAGPGTCTFDHRHLYTKKVTEDALIRTVSYNILADTYAQTEFSRTVLYPYCAPYALELDYRQNLIQKELTGYNADVICLQEVDRAVFSDSLVPALEAFGLEGVFRIKQH---EGLATFYRKSKFSLLSQHDI---SFYEALESDPLHKELLEKLVLYPSAQEKVLQRSSVLQVSVLQSTKDSS-KRICVANTHLYWHPKGGYIRLIQMAVALAHIRH-------VSCDLYPGIPVIFCG 495 HSP 2 Score: 59.6918 bits (143), Expect = 9.167e-9 Identity = 34/116 (29.31%), Postives = 64/116 (55.17%), Query Frame = 3
Query: 1347 VVIGGDFNASFDAELMRFILDKSV-----ECSLVNNAIKLNHSLGDFYSVFKDKIE--FTNFTPDYVGVLDHIVIDCSGLEVKHLYDVPNRLDIAKNISLPNEFHPSDHLPLLCDI 1673
V+ GDFN++ + F+++ S+ + + + N SL F+ + E +TN+ + G LD+I ID + LEV+ + +P+ ++ + +LP+ HPSDH+ L+CD+
Sbjct: 491 VIFCGDFNSTPSTGMYHFVINGSIPEDHEDWASNGEEERCNMSLTHFFKLKSACGEPAYTNYVGGFHGCLDYIFIDLNALEVEQVIPLPSHEEVTTHQALPSVSHPSDHIALVCDL 606
BLAST of Endo/exonuclease/phosphatase domain-containing protein vs. Ensembl Human
Match: PDE12 (phosphodiesterase 12 [Source:HGNC Symbol;Acc:HGNC:25386]) HSP 1 Score: 111.694 bits (278), Expect = 1.339e-25 Identity = 93/368 (25.27%), Postives = 161/368 (43.75%), Query Frame = 2
Query: 266 PIDYCEIFALDIKNQNKICISDLTINDLLISNILIKINEVIYQIYFKPPWIKTCKLPKITMVNIPITPILDLENVNESELSINWYVSKSSSSDD-----------------WIKCHTGT-IFIPSENYLNFFIKLQVNSTLRNK-NQNFQLISTSPIQQYPQM-EYQKLNLFNP-ILSDKTFRICSYNILSHIYAETDKAKSVLYRHCNPEFLTRDYRQCLIFGELLQHKSDIIFLQEVDQSFYQKSLYPILQSYNYEGIFQKKSRTNWEGQAIFWNINKFKLIDNISIPSLSMVINEENSEVYKKIKRFLRDTNLYNKWQST----GQCMTGCVLETVSLADRKRLMLCNNHLICDPKLEIFRLFQL 1294
P +CE + + + + D+ D +++I +V Y++ PP +LP+ M P+ P L LE + + WY + + W + ++ PS + +KL + + +L S ++ P + +L+ + D R SYNIL+ YA+T+ +++VLY +C P L DYRQ LI EL + +D+I LQEVD++ + SL P L+++ EG+F+ K EG A F+ +KF L+ I S E+ ++K++ L LY Q + VL++ + KR+ + N HL PK + + Q+
Sbjct: 115 PAVFCEPV-VKLYYREEAVAEDVLNVDAWQDGAVLQIGDVKYKVERNPPAFTELQLPRYIMAGFPVCPKLSLEFGDPASSLFRWYKEAKPGAAEPEVGVPSSLSPSSPSSSWTETDVEERVYTPSNADIGLRLKLHCTPGDGQRFGHSRELESVCVVEAGPGTCTFDHRHLYTKKVTEDALIRTVSYNILADTYAQTEFSRTVLYPYCAPYALELDYRQNLIQKELTGYNADVICLQEVDRAVFSDSLVPALEAFGLEGVFRIKQH---EGLATFYRKSKFSLLSQHDI---SFYEALESDPLHKEL---LEKLVLYPSAQEKVLQRSSVLQVSVLQSTKDSS-KRICVANTHLYWHPKGRFYLVSQV 471
BLAST of Endo/exonuclease/phosphatase domain-containing protein vs. Ensembl Human
Match: CNOT6L (CCR4-NOT transcription complex subunit 6 like [Source:HGNC Symbol;Acc:HGNC:18042]) HSP 1 Score: 69.3218 bits (168), Expect = 6.632e-12 Identity = 62/228 (27.19%), Postives = 103/228 (45.18%), Query Frame = 2
Query: 650 NFQL--ISTSPIQQYPQMEYQKLNLFNPILSDKTFRICSYNILSHIYAETDKAKSVLYRHCNPEFLTRDYRQCLIFGELLQHKSDIIFLQEVDQSFYQKSLYPILQSYNYEGIFQKKSRT---------NWEGQAIFWNINKFKLIDNISIP--SLSMVINEENSEVYKKIKRFLRDTNL-YNKWQSTGQCMTGCVLETVSLADRKRLMLCNNHLICDPKLEIFRLFQ 1291
NF L ++ P +Q P + L + IL +F + YN+L YA LY +C L +YR+ I E++ +DII LQEV+ Y P L+ Y+G F KSR + +G AIF+ KF L+ ++ ++M N + SE + R + N+ + + G ++ + AD++ L++ N H+ DP+ +L Q
Sbjct: 151 NFMLDNLAVHP-EQLPPRPWITLKERDQILPSASFTVMCYNVLCDKYATRQ-----LYGYCPSWALNWEYRKKGIMEEIVNCDADIISLQEVETEQYFTLFLPALKERGYDGFFSPKSRAKIMSEQERKHVDGCAIFFKTEKFTLVQKHTVEFNQVAMA-NSDGSEAM--LNRVMTKDNIGVAVVLEVHKELFGAGMKPIHAADKQLLIVANAHMHWDPEYSDVKLIQ 369
BLAST of Endo/exonuclease/phosphatase domain-containing protein vs. Ensembl Human
Match: CNOT6L (CCR4-NOT transcription complex subunit 6 like [Source:HGNC Symbol;Acc:HGNC:18042]) HSP 1 Score: 68.9366 bits (167), Expect = 1.105e-11 Identity = 61/227 (26.87%), Postives = 102/227 (44.93%), Query Frame = 2
Query: 650 NFQL--ISTSPIQQYPQMEYQKLNLFNPILSDKTFRICSYNILSHIYAETDKAKSVLYRHCNPEFLTRDYRQCLIFGELLQHKSDIIFLQEVDQSFYQKSLYPILQSYNYEGIFQKKSRT---------NWEGQAIFWNINKFKLIDNISIP-SLSMVINEENSEVYKKIKRFLRDTNL-YNKWQSTGQCMTGCVLETVSLADRKRLMLCNNHLICDPKLEIFRLFQ 1291
NF L ++ P +Q P + L + IL +F + YN+L YA LY +C L +YR+ I E++ +DII LQEV+ Y P L+ Y+G F KSR + +G AIF+ KF L+ ++ + + N + SE + R + N+ + + G ++ + AD++ L++ N H+ DP+ +L Q
Sbjct: 151 NFMLDNLAVHP-EQLPPRPWITLKERDQILPSASFTVMCYNVLCDKYATRQ-----LYGYCPSWALNWEYRKKGIMEEIVNCDADIISLQEVETEQYFTLFLPALKERGYDGFFSPKSRAKIMSEQERKHVDGCAIFFKTEKFTLVQKHTVEFNQVAMANSDGSEAM--LNRVMTKDNIGVAVVLEVHKELFGAGMKPIHAADKQLLIVANAHMHWDPEYSDVKLIQ 369
BLAST of Endo/exonuclease/phosphatase domain-containing protein vs. Ensembl Human
Match: CNOT6L (CCR4-NOT transcription complex subunit 6 like [Source:HGNC Symbol;Acc:HGNC:18042]) HSP 1 Score: 68.9366 bits (167), Expect = 1.105e-11 Identity = 61/227 (26.87%), Postives = 102/227 (44.93%), Query Frame = 2
Query: 650 NFQL--ISTSPIQQYPQMEYQKLNLFNPILSDKTFRICSYNILSHIYAETDKAKSVLYRHCNPEFLTRDYRQCLIFGELLQHKSDIIFLQEVDQSFYQKSLYPILQSYNYEGIFQKKSRT---------NWEGQAIFWNINKFKLIDNISIP-SLSMVINEENSEVYKKIKRFLRDTNL-YNKWQSTGQCMTGCVLETVSLADRKRLMLCNNHLICDPKLEIFRLFQ 1291
NF L ++ P +Q P + L + IL +F + YN+L YA LY +C L +YR+ I E++ +DII LQEV+ Y P L+ Y+G F KSR + +G AIF+ KF L+ ++ + + N + SE + R + N+ + + G ++ + AD++ L++ N H+ DP+ +L Q
Sbjct: 151 NFMLDNLAVHP-EQLPPRPWITLKERDQILPSASFTVMCYNVLCDKYATRQ-----LYGYCPSWALNWEYRKKGIMEEIVNCDADIISLQEVETEQYFTLFLPALKERGYDGFFSPKSRAKIMSEQERKHVDGCAIFFKTEKFTLVQKHTVEFNQVAMANSDGSEAM--LNRVMTKDNIGVAVVLEVHKELFGAGMKPIHAADKQLLIVANAHMHWDPEYSDVKLIQ 369
BLAST of Endo/exonuclease/phosphatase domain-containing protein vs. Ensembl Celegans
Match: ccr-4 (CCR (Yeast CCR4/NOT complex component) homolog [Source:UniProtKB/TrEMBL;Acc:A0A061AD13]) HSP 1 Score: 65.4698 bits (158), Expect = 5.587e-11 Identity = 39/130 (30.00%), Postives = 64/130 (49.23%), Query Frame = 2
Query: 689 PQMEYQKLNLFNPILSDKTFRICSYNILSHIYAETDKAKSVLYRHCNPEFLTRDYRQCLIFGELLQHKSDIIFLQEVDQSFYQKSLYPILQSYNYEGIFQKKSRTNWEGQ---------AIFWNINKFKL 1051
P+ + + +P TF + YN+L YA ++ Y +C L +YR+ LI E+ +++D+I LQEV+ ++ P L+ Y GIF+ KSR G+ AIFW ++KF +
Sbjct: 192 PERNWVMIRHADPERPIATFTVLCYNVLCDKYATVNQ-----YSYCPSWALNWEYRKGLIIKEIRTYEADVITLQEVETEQFRTLFQPELKQLGYAGIFEAKSRAKTMGEEERKYVDGCAIFWKVDKFDM 316
BLAST of Endo/exonuclease/phosphatase domain-containing protein vs. Ensembl Celegans
Match: ccr-4 (CCR (Yeast CCR4/NOT complex component) homolog [Source:UniProtKB/TrEMBL;Acc:A0A061AD13]) HSP 1 Score: 65.4698 bits (158), Expect = 5.587e-11 Identity = 39/130 (30.00%), Postives = 64/130 (49.23%), Query Frame = 2
Query: 689 PQMEYQKLNLFNPILSDKTFRICSYNILSHIYAETDKAKSVLYRHCNPEFLTRDYRQCLIFGELLQHKSDIIFLQEVDQSFYQKSLYPILQSYNYEGIFQKKSRTNWEGQ---------AIFWNINKFKL 1051
P+ + + +P TF + YN+L YA ++ Y +C L +YR+ LI E+ +++D+I LQEV+ ++ P L+ Y GIF+ KSR G+ AIFW ++KF +
Sbjct: 192 PERNWVMIRHADPERPIATFTVLCYNVLCDKYATVNQ-----YSYCPSWALNWEYRKGLIIKEIRTYEADVITLQEVETEQFRTLFQPELKQLGYAGIFEAKSRAKTMGEEERKYVDGCAIFWKVDKFDM 316
BLAST of Endo/exonuclease/phosphatase domain-containing protein vs. Ensembl Celegans
Match: ccr-4 (CCR (Yeast CCR4/NOT complex component) homolog [Source:UniProtKB/TrEMBL;Acc:A0A061AD13]) HSP 1 Score: 65.4698 bits (158), Expect = 5.649e-11 Identity = 39/130 (30.00%), Postives = 64/130 (49.23%), Query Frame = 2
Query: 689 PQMEYQKLNLFNPILSDKTFRICSYNILSHIYAETDKAKSVLYRHCNPEFLTRDYRQCLIFGELLQHKSDIIFLQEVDQSFYQKSLYPILQSYNYEGIFQKKSRTNWEGQ---------AIFWNINKFKL 1051
P+ + + +P TF + YN+L YA ++ Y +C L +YR+ LI E+ +++D+I LQEV+ ++ P L+ Y GIF+ KSR G+ AIFW ++KF +
Sbjct: 201 PERNWVMIRHADPERPIATFTVLCYNVLCDKYATVNQ-----YSYCPSWALNWEYRKGLIIKEIRTYEADVITLQEVETEQFRTLFQPELKQLGYAGIFEAKSRAKTMGEEERKYVDGCAIFWKVDKFDM 325
BLAST of Endo/exonuclease/phosphatase domain-containing protein vs. Ensembl Celegans
Match: angl-1 (ANGeL-like deadenylase [Source:UniProtKB/TrEMBL;Acc:A0A0M9JJ86]) HSP 1 Score: 63.929 bits (154), Expect = 6.433e-11 Identity = 54/210 (25.71%), Postives = 100/210 (47.62%), Query Frame = 2
Query: 725 PILSDKTFRICSYNILSH-IYAETDKAKSVLYRH--CNPEFLTRDYRQCLIFGELLQHKSDIIFLQEVDQSFYQKSLYPILQSYNYEGIFQKKSRTNW--EGQAIFWNINKFKLIDNISIPSLSMVINEENSEVYKKIKRFLRDTNLYNKWQSTGQCMTGCVLETVSLADRKRLMLCNNHLICDPKLEIFRLFQLAVGMLQLEQIKYQYG 1339
P +S K F ICSYN+L A TD LYRH + +FL ++R + EL +DI+ LQEV + + P+++ Y YEG++++K T +G A+F++ KF+L+ N +++ F+ DT + N+ C + ++ +++ N HL+ + + +L QLA+ + +++ +
Sbjct: 65 PKISSK-FTICSYNVLCQKTIARTD----YLYRHLQGSAQFLDWEHRWRGLQVELPTFDADILGLQEVQADHFVEHFQPLMKKYGYEGVYKQKFGTQQKDDGCALFYHPAKFELVAN------------------QEVNYFISDTAISNRENIAQIVALRCRIT------KELILVANTHLLFNEERGDVKLAQLAILFASIHKMREDFA 245
BLAST of Endo/exonuclease/phosphatase domain-containing protein vs. Ensembl Celegans
Match: angl-1 (ANGeL-like deadenylase [Source:UniProtKB/TrEMBL;Acc:A0A0M9JJ86]) HSP 1 Score: 63.929 bits (154), Expect = 6.433e-11 Identity = 54/210 (25.71%), Postives = 100/210 (47.62%), Query Frame = 2
Query: 725 PILSDKTFRICSYNILSH-IYAETDKAKSVLYRH--CNPEFLTRDYRQCLIFGELLQHKSDIIFLQEVDQSFYQKSLYPILQSYNYEGIFQKKSRTNW--EGQAIFWNINKFKLIDNISIPSLSMVINEENSEVYKKIKRFLRDTNLYNKWQSTGQCMTGCVLETVSLADRKRLMLCNNHLICDPKLEIFRLFQLAVGMLQLEQIKYQYG 1339
P +S K F ICSYN+L A TD LYRH + +FL ++R + EL +DI+ LQEV + + P+++ Y YEG++++K T +G A+F++ KF+L+ N +++ F+ DT + N+ C + ++ +++ N HL+ + + +L QLA+ + +++ +
Sbjct: 65 PKISSK-FTICSYNVLCQKTIARTD----YLYRHLQGSAQFLDWEHRWRGLQVELPTFDADILGLQEVQADHFVEHFQPLMKKYGYEGVYKQKFGTQQKDDGCALFYHPAKFELVAN------------------QEVNYFISDTAISNRENIAQIVALRCRIT------KELILVANTHLLFNEERGDVKLAQLAILFASIHKMREDFA 245
BLAST of Endo/exonuclease/phosphatase domain-containing protein vs. Ensembl Fly
Match: CG31759 (gene:FBgn0051759 transcript:FBtr0290240) HSP 1 Score: 131.724 bits (330), Expect = 1.536e-36 Identity = 116/444 (26.13%), Postives = 205/444 (46.17%), Query Frame = 2
Query: 59 LNHIFIRNSDQINNHVLIEFEYSFENSS-SLYYSFLRPISESLEVLFNKMISKLYFSSNKRKNKKIKTEIPIDYCEIFALDIKNQNKICISDLTINDLL----ISNILIKINEVIYQIYFKPPWIKTCK-LPKITMVNIPITPILDLENVNESELS-INWYVSKSSSSDDWIKCHTGTIFIPSENYLNFFIKLQV--NSTLRNKNQNFQLISTSPIQQYPQ---MEYQKLNLFNPILSDKTFRICSYNILSHIYAETDKAKSVLYRHCNPEFLTRDYRQCLIFGELLQHKSDIIFLQEVDQSFYQKSLYPILQS--YNYEGIFQKKSRTNWEGQAIFWNINKFKLID------NISIPSLSMVINEENSEVYKKIKRFLRDTNLYNKWQSTGQCMTGCVLETVSL---ADRKRLMLCNNHLICDPKLEIFRLFQLAVGMLQLEQ 1321
+ +++RN+ + I F + EN + ++F R ++E ++ + ++ S + + KK K + P EI + ++ ++LT DL+ ISN+ +++ + +Y + F PPWI + K LP + I P E + S W+ +K + DW C G ++ + + + +K V + L + I+ S +Q+ P + ++ + N + R+ SYN+L+ +YA +D A S L+ +C ++L DYR+ L E++ + SDI+ LQEVDQ + L IL+ YNY GI K + EG AIF+ ++F L+D +IP+L + ++ KIK N + C L+T L +++ N HL P + RL Q+ ML +EQ
Sbjct: 1 MEKVYLRNASD-TKELDIVFRFVNENLKINREFNFRRQMNEPIDAILARIQSNI-IGRLAKSCKKSKIKPP---AEINVKLLSDKYGEKFNELTFEDLVVTQDISNVKLQVLDTVYDLVFNPPWISSLKFLPSCILAGFVIYPTNVQIQFGERQFSKAVWFKAKKPTDTDWEVCGEGFQYLVTPEDIGYHLKFVVTPGNALGMTGPVVEKITNSAVQESPGRCPFQDRQRHTTNSLSESNEIRVVSYNLLADLYASSDYAGSTLFSYCPAKYLQIDYRKPLFINEIIGYNSDILCLQEVDQRIFDFDLKEILEQPPYNYHGIMAPKGKCA-EGVAIFFRNSRFDLLDSQILHLGSNIPALPVF-----ESLWNKIK--------VNAQLAERICERSTTLQTCLLRIKGTDNYVLVANTHLYFHPDADHIRLLQMGFSMLFVEQ 425 HSP 2 Score: 41.5874 bits (96), Expect = 1.536e-36 Identity = 25/116 (21.55%), Postives = 55/116 (47.41%), Query Frame = 3
Query: 1347 VVIGGDFNASFDAELMRFILDKSVECSLVNNAIKLNHSLG--DFYSVFK-----DKIEFTNFTPDYVGVLDHIVIDCSGLEVKHLYDVPNRLDIAKNISLPNEFHPSDHLPLLCDI 1673
++ GDFN+ + + + + ++ E +L + ++ + FK E+T++T + G LD++ EV + +P ++ N ++P+ PSDH+ L+ D+
Sbjct: 444 LIFCGDFNSVPECGIYKLMTEQLAEKTLEDWQSNAEQAVSNVELAQPFKMASAYGAPEYTHYTTLFAGCLDYVFYQNDRFEVLKVVPLPTEEELKANTAIPSAVFPSDHVALVADL 559
BLAST of Endo/exonuclease/phosphatase domain-containing protein vs. Ensembl Fly
Match: CG31759 (gene:FBgn0051759 transcript:FBtr0290239) HSP 1 Score: 131.724 bits (330), Expect = 1.536e-36 Identity = 116/444 (26.13%), Postives = 205/444 (46.17%), Query Frame = 2
Query: 59 LNHIFIRNSDQINNHVLIEFEYSFENSS-SLYYSFLRPISESLEVLFNKMISKLYFSSNKRKNKKIKTEIPIDYCEIFALDIKNQNKICISDLTINDLL----ISNILIKINEVIYQIYFKPPWIKTCK-LPKITMVNIPITPILDLENVNESELS-INWYVSKSSSSDDWIKCHTGTIFIPSENYLNFFIKLQV--NSTLRNKNQNFQLISTSPIQQYPQ---MEYQKLNLFNPILSDKTFRICSYNILSHIYAETDKAKSVLYRHCNPEFLTRDYRQCLIFGELLQHKSDIIFLQEVDQSFYQKSLYPILQS--YNYEGIFQKKSRTNWEGQAIFWNINKFKLID------NISIPSLSMVINEENSEVYKKIKRFLRDTNLYNKWQSTGQCMTGCVLETVSL---ADRKRLMLCNNHLICDPKLEIFRLFQLAVGMLQLEQ 1321
+ +++RN+ + I F + EN + ++F R ++E ++ + ++ S + + KK K + P EI + ++ ++LT DL+ ISN+ +++ + +Y + F PPWI + K LP + I P E + S W+ +K + DW C G ++ + + + +K V + L + I+ S +Q+ P + ++ + N + R+ SYN+L+ +YA +D A S L+ +C ++L DYR+ L E++ + SDI+ LQEVDQ + L IL+ YNY GI K + EG AIF+ ++F L+D +IP+L + ++ KIK N + C L+T L +++ N HL P + RL Q+ ML +EQ
Sbjct: 1 MEKVYLRNASD-TKELDIVFRFVNENLKINREFNFRRQMNEPIDAILARIQSNI-IGRLAKSCKKSKIKPP---AEINVKLLSDKYGEKFNELTFEDLVVTQDISNVKLQVLDTVYDLVFNPPWISSLKFLPSCILAGFVIYPTNVQIQFGERQFSKAVWFKAKKPTDTDWEVCGEGFQYLVTPEDIGYHLKFVVTPGNALGMTGPVVEKITNSAVQESPGRCPFQDRQRHTTNSLSESNEIRVVSYNLLADLYASSDYAGSTLFSYCPAKYLQIDYRKPLFINEIIGYNSDILCLQEVDQRIFDFDLKEILEQPPYNYHGIMAPKGKCA-EGVAIFFRNSRFDLLDSQILHLGSNIPALPVF-----ESLWNKIK--------VNAQLAERICERSTTLQTCLLRIKGTDNYVLVANTHLYFHPDADHIRLLQMGFSMLFVEQ 425 HSP 2 Score: 41.5874 bits (96), Expect = 1.536e-36 Identity = 25/116 (21.55%), Postives = 55/116 (47.41%), Query Frame = 3
Query: 1347 VVIGGDFNASFDAELMRFILDKSVECSLVNNAIKLNHSLG--DFYSVFK-----DKIEFTNFTPDYVGVLDHIVIDCSGLEVKHLYDVPNRLDIAKNISLPNEFHPSDHLPLLCDI 1673
++ GDFN+ + + + + ++ E +L + ++ + FK E+T++T + G LD++ EV + +P ++ N ++P+ PSDH+ L+ D+
Sbjct: 444 LIFCGDFNSVPECGIYKLMTEQLAEKTLEDWQSNAEQAVSNVELAQPFKMASAYGAPEYTHYTTLFAGCLDYVFYQNDRFEVLKVVPLPTEEELKANTAIPSAVFPSDHVALVADL 559
BLAST of Endo/exonuclease/phosphatase domain-containing protein vs. Ensembl Fly
Match: twin (gene:FBgn0011725 transcript:FBtr0084567) HSP 1 Score: 58.9214 bits (141), Expect = 2.537e-13 Identity = 61/229 (26.64%), Postives = 96/229 (41.92%), Query Frame = 2
Query: 665 STSPIQQYPQMEYQKLNLFNPILSDKTFRICSYNILSHIYAETDKAKSVLYRHCNPEFLTRDYRQCLIFGELLQHKSDIIFLQEVDQSFYQKSLYPILQSYNYEGIFQKKSRTNW---------EGQAIFWNINKFKLIDN--ISIPSLSMVINEENSEVYKKIKRFLRDTNLY---------NKWQSTGQCMTGCVLETVSLADRKRLMLCNNHLICDPKLEIFRLFQ 1291
+ +P Q P + K N P F + YN+L YA +Y +C L +YR+ I E+ + +DII LQE++ + P L++ YEGIF KSR +G AIF+ +KF LI I L+M N E S+ + R + N+ N W+ + + +S + L++C H+ DP+ +L Q
Sbjct: 161 TVNPPPQRPWLPLAKPNKTRPAC---IFTVMCYNVLCDKYATRQ-----MYGYCPSWALCWEYRKKSIIDEIRHYAADIISLQEIETEQFYHFFLPELKNDGYEGIFSPKSRAKTMSELERKYVDGCAIFFRASKFTLIKESLIEFNQLAMA-NAEGSD--NMLNRVMPKDNIGLAALLKVKENAWEPMSE------VTQIS----QPLLVCTAHIHWDPEFCDVKLIQ 368 HSP 2 Score: 35.8094 bits (81), Expect = 2.537e-13 Identity = 35/134 (26.12%), Postives = 63/134 (47.01%), Query Frame = 3
Query: 1326 NTNTVKCVVIGGDFNASFDAELMRFILDKSVECS----------------LVNNAIKLNHSLGDFYSVFKDKIEFTNFTPDYVGVLDHIVIDCSGL-EVKHLYDVPN-RLDIAKNISLPNEFHPSDHLPLLCDI 1673
++N V+ +++ GDFN+ D+ ++ F+ V L N+ + HS + +D + TN+T D+ G++D+I +G+ + L V N L K + P+ PSDH PLL ++
Sbjct: 394 DSNAVQ-LLLCGDFNSLPDSGVVEFLGKGRVSMDHLDFKDMGYKSCLQRLLSNDTNEFTHSFKLASAYNEDIMPHTNYTFDFKGIIDYIFYTKTGMVPLGLLGPVSNDWLRENKVVGCPHPHIPSDHFPLLVEL 526
BLAST of Endo/exonuclease/phosphatase domain-containing protein vs. Ensembl Fly
Match: twin (gene:FBgn0011725 transcript:FBtr0084569) HSP 1 Score: 58.9214 bits (141), Expect = 2.576e-13 Identity = 61/229 (26.64%), Postives = 96/229 (41.92%), Query Frame = 2
Query: 665 STSPIQQYPQMEYQKLNLFNPILSDKTFRICSYNILSHIYAETDKAKSVLYRHCNPEFLTRDYRQCLIFGELLQHKSDIIFLQEVDQSFYQKSLYPILQSYNYEGIFQKKSRTNW---------EGQAIFWNINKFKLIDN--ISIPSLSMVINEENSEVYKKIKRFLRDTNLY---------NKWQSTGQCMTGCVLETVSLADRKRLMLCNNHLICDPKLEIFRLFQ 1291
+ +P Q P + K N P F + YN+L YA +Y +C L +YR+ I E+ + +DII LQE++ + P L++ YEGIF KSR +G AIF+ +KF LI I L+M N E S+ + R + N+ N W+ + + +S + L++C H+ DP+ +L Q
Sbjct: 183 TVNPPPQRPWLPLAKPNKTRPAC---IFTVMCYNVLCDKYATRQ-----MYGYCPSWALCWEYRKKSIIDEIRHYAADIISLQEIETEQFYHFFLPELKNDGYEGIFSPKSRAKTMSELERKYVDGCAIFFRASKFTLIKESLIEFNQLAMA-NAEGSD--NMLNRVMPKDNIGLAALLKVKENAWEPMSE------VTQIS----QPLLVCTAHIHWDPEFCDVKLIQ 390 HSP 2 Score: 35.8094 bits (81), Expect = 2.576e-13 Identity = 35/134 (26.12%), Postives = 63/134 (47.01%), Query Frame = 3
Query: 1326 NTNTVKCVVIGGDFNASFDAELMRFILDKSVECS----------------LVNNAIKLNHSLGDFYSVFKDKIEFTNFTPDYVGVLDHIVIDCSGL-EVKHLYDVPN-RLDIAKNISLPNEFHPSDHLPLLCDI 1673
++N V+ +++ GDFN+ D+ ++ F+ V L N+ + HS + +D + TN+T D+ G++D+I +G+ + L V N L K + P+ PSDH PLL ++
Sbjct: 416 DSNAVQ-LLLCGDFNSLPDSGVVEFLGKGRVSMDHLDFKDMGYKSCLQRLLSNDTNEFTHSFKLASAYNEDIMPHTNYTFDFKGIIDYIFYTKTGMVPLGLLGPVSNDWLRENKVVGCPHPHIPSDHFPLLVEL 548
BLAST of Endo/exonuclease/phosphatase domain-containing protein vs. Ensembl Fly
Match: twin (gene:FBgn0011725 transcript:FBtr0084566) HSP 1 Score: 58.9214 bits (141), Expect = 2.986e-13 Identity = 61/229 (26.64%), Postives = 96/229 (41.92%), Query Frame = 2
Query: 665 STSPIQQYPQMEYQKLNLFNPILSDKTFRICSYNILSHIYAETDKAKSVLYRHCNPEFLTRDYRQCLIFGELLQHKSDIIFLQEVDQSFYQKSLYPILQSYNYEGIFQKKSRTNW---------EGQAIFWNINKFKLIDN--ISIPSLSMVINEENSEVYKKIKRFLRDTNLY---------NKWQSTGQCMTGCVLETVSLADRKRLMLCNNHLICDPKLEIFRLFQ 1291
+ +P Q P + K N P F + YN+L YA +Y +C L +YR+ I E+ + +DII LQE++ + P L++ YEGIF KSR +G AIF+ +KF LI I L+M N E S+ + R + N+ N W+ + + +S + L++C H+ DP+ +L Q
Sbjct: 168 TVNPPPQRPWLPLAKPNKTRPAC---IFTVMCYNVLCDKYATRQ-----MYGYCPSWALCWEYRKKSIIDEIRHYAADIISLQEIETEQFYHFFLPELKNDGYEGIFSPKSRAKTMSELERKYVDGCAIFFRASKFTLIKESLIEFNQLAMA-NAEGSD--NMLNRVMPKDNIGLAALLKVKENAWEPMSE------VTQIS----QPLLVCTAHIHWDPEFCDVKLIQ 375 HSP 2 Score: 35.8094 bits (81), Expect = 2.986e-13 Identity = 35/134 (26.12%), Postives = 63/134 (47.01%), Query Frame = 3
Query: 1326 NTNTVKCVVIGGDFNASFDAELMRFILDKSVECS----------------LVNNAIKLNHSLGDFYSVFKDKIEFTNFTPDYVGVLDHIVIDCSGL-EVKHLYDVPN-RLDIAKNISLPNEFHPSDHLPLLCDI 1673
++N V+ +++ GDFN+ D+ ++ F+ V L N+ + HS + +D + TN+T D+ G++D+I +G+ + L V N L K + P+ PSDH PLL ++
Sbjct: 401 DSNAVQ-LLLCGDFNSLPDSGVVEFLGKGRVSMDHLDFKDMGYKSCLQRLLSNDTNEFTHSFKLASAYNEDIMPHTNYTFDFKGIIDYIFYTKTGMVPLGLLGPVSNDWLRENKVVGCPHPHIPSDHFPLLVEL 533
BLAST of Endo/exonuclease/phosphatase domain-containing protein vs. Ensembl Zebrafish
Match: pde12 (phosphodiesterase 12 [Source:ZFIN;Acc:ZDB-GENE-060519-25]) HSP 1 Score: 139.813 bits (351), Expect = 7.225e-35 Identity = 107/400 (26.75%), Postives = 201/400 (50.25%), Query Frame = 2
Query: 167 PISESLEVLFNKMISKLYFSSNKRKNKKIKTEIPIDYCEIFALDIKNQNKICISDLTIN-DLLISNILIKINEVIYQIYFKPPWIKTCKLPKITMVNIPITPILDLENVNESELSINWYVSKSSSS------DDWIKCHTGTIFIPSENYLNFFIKLQVNSTLRNK---NQNFQLISTSPIQQYPQM-EYQKLNLFNPILSDK-TFRICSYNILSHIYAETDKAKSVLYRHCNPEFLTRDYRQCLIFGELLQHKSDIIFLQEVDQSFYQKSLYPILQSYNYEGIFQKKSRTNWEGQAIFWNINKFKLIDNISIP-SLSMVINEENSEVYKKIKRFLRDTNLYNKWQSTGQCMTGCVLETVSLADRKRLM-LCNNHLICDPKLEIFRLFQLAVGMLQLEQI 1324
P+ + L+ + N + S K K K K E +L + Q +S T+N D ++++ ++ Y++ PP +LP M P+ P +++E + + W+ S+S+ + W + + +F PS L+ ++L + T N + +L+S+S ++ P + + +++ L+D+ + R+ SYNIL+ +YA+TD +K+VLY +C P L DYRQ LI EL + +DII LQEVD+ + L P L ++ +G+F+ K + + EG A ++ +K KL++ + S ++ + + E+++K+ +L K + + VL+ SL D R++ + N HL P+ RL Q+AV + ++Q+
Sbjct: 71 PLGKLLDRIANNSVKTTAGKSKKHKPSKEKPESQEAEKPETSLSVNGQP---VSPETLNSDAWEDGAVLQVGDLKYKVERNPPTFTQSELPSSLMAGFPVCPKIEIEFGDLKDCEFRWFKESSASAYITGDAECWREAGSERVFTPSN--LDIGLRLMLKCTPGNGSKIGEPKKLVSSSAVEAGPGICTFDNRHIYTQKLTDEGSLRVVSYNILADVYAQTDLSKTVLYPYCAPYALQMDYRQNLIKKELSGYNADIICLQEVDKCVFVDVLCPALDAFGLDGVFRIKEKQH-EGLATYFRRSKLKLVEQYDVMLSEALTTDPIHRELWEKVS---CSPSLKEKIEKRSTTLQVTVLQ--SLCDPSRILCVGNTHLYWRPEGGNVRLVQIAVALEHMKQV 459 HSP 2 Score: 51.2174 bits (121), Expect = 2.787e-6 Identity = 21/59 (35.59%), Postives = 40/59 (67.80%), Query Frame = 3
Query: 1497 EFTNFTPDYVGVLDHIVIDCSGLEVKHLYDVPNRLDIAKNISLPNEFHPSDHLPLLCDI 1673
+FTNF + G LD+I ++ L+V+ + +P+ +++ ++LP+ HPSDH+ L+CD+
Sbjct: 526 DFTNFVGGFQGCLDYIFVEPRTLQVEQVIPLPSLEEVSNCVALPSISHPSDHIALVCDL 584
BLAST of Endo/exonuclease/phosphatase domain-containing protein vs. Ensembl Zebrafish
Match: cnot6a (CCR4-NOT transcription complex, subunit 6a [Source:ZFIN;Acc:ZDB-GENE-030131-2768]) HSP 1 Score: 63.1586 bits (152), Expect = 4.620e-10 Identity = 62/239 (25.94%), Postives = 102/239 (42.68%), Query Frame = 2
Query: 650 NFQLISTSPIQQYPQMEYQKLNLFNPILSDKTFRICSYNILSHIYAETDKAKSVLYRHCNPEFLTRDYRQCLIFGELLQHKSDIIFLQEVDQSFYQKSLYPILQSYNYEGIFQKKSRT---------NWEGQAIFWNINKFKLIDNISIP--SLSMVINEENSEVYKKIKRFLRDTNLYNK--WQSTGQCMTGCVLETVSLADRKRLMLCNNHLICDPKLEIFRLFQLAVGMLQLEQIK 1327
N +PI+Q P + L + F + YN+L YA LY +C L +YR+ I E+L +DII LQEV+ Y L+ YEG F KSR + +G A+F+ +KF L+ ++ L+M N E SE + R + N+ + + M + + +++ L++ N H+ DP+ +L Q M+ L ++K
Sbjct: 156 NLAGTKRAPIEQPPPRSWIPLQEPDRTRPAALFSVMCYNVLCDKYATRQ-----LYGYCPSWALNWEYRKKSIMQEILSCSADIISLQEVETEQYYNYFLLELKEQGYEGFFSPKSRARTMSESDRKHVDGCAVFYKTDKFSLVQKHTVEFNQLAMA-NSEGSEAM--LNRVMTKDNIGVAVLLELRKEMMELSAGKPLHGMEKQLLLVANAHMHWDPEYSDVKLVQT---MMFLSEVK 383
BLAST of Endo/exonuclease/phosphatase domain-containing protein vs. Ensembl Zebrafish
Match: cnot6a (CCR4-NOT transcription complex, subunit 6a [Source:ZFIN;Acc:ZDB-GENE-030131-2768]) HSP 1 Score: 63.1586 bits (152), Expect = 4.620e-10 Identity = 62/239 (25.94%), Postives = 102/239 (42.68%), Query Frame = 2
Query: 650 NFQLISTSPIQQYPQMEYQKLNLFNPILSDKTFRICSYNILSHIYAETDKAKSVLYRHCNPEFLTRDYRQCLIFGELLQHKSDIIFLQEVDQSFYQKSLYPILQSYNYEGIFQKKSRT---------NWEGQAIFWNINKFKLIDNISIP--SLSMVINEENSEVYKKIKRFLRDTNLYNK--WQSTGQCMTGCVLETVSLADRKRLMLCNNHLICDPKLEIFRLFQLAVGMLQLEQIK 1327
N +PI+Q P + L + F + YN+L YA LY +C L +YR+ I E+L +DII LQEV+ Y L+ YEG F KSR + +G A+F+ +KF L+ ++ L+M N E SE + R + N+ + + M + + +++ L++ N H+ DP+ +L Q M+ L ++K
Sbjct: 156 NLAGTKRAPIEQPPPRSWIPLQEPDRTRPAALFSVMCYNVLCDKYATRQ-----LYGYCPSWALNWEYRKKSIMQEILSCSADIISLQEVETEQYYNYFLLELKEQGYEGFFSPKSRARTMSESDRKHVDGCAVFYKTDKFSLVQKHTVEFNQLAMA-NSEGSEAM--LNRVMTKDNIGVAVLLELRKEMMELSAGKPLHGMEKQLLLVANAHMHWDPEYSDVKLVQT---MMFLSEVK 383
BLAST of Endo/exonuclease/phosphatase domain-containing protein vs. Ensembl Zebrafish
Match: angel2 (angel homolog 2 (Drosophila) [Source:NCBI gene;Acc:562704]) HSP 1 Score: 61.6178 bits (148), Expect = 1.699e-9 Identity = 50/193 (25.91%), Postives = 90/193 (46.63%), Query Frame = 2
Query: 746 FRICSYNILSHIYAETDKAKSVLYRHCNPEFLTRDYRQCLIFGELLQHKSDIIFLQEVDQSFYQKSLYPILQSYNYEGIFQKKSRTNWEGQAIFWNINKFKLIDNISIPSLSMVINEENSEVYKKIKRFLRDTNLYNKWQSTGQCMTGCVLETVSLADRKRLMLCNNHLICDPKLEIFRLFQLAVGMLQLEQI 1324
F + SYNILS + + LYRHCNP L R I EL Q+ +DI+ LQEV + Y++ + P L+S Y F++++ +G A+ + +F L+ ++ F R L ++ + + VSL++ + + N HL+ +P+ +L QLA+ + ++ ++
Sbjct: 199 FSVMSYNILSQDLLCDN---TYLYRHCNPPVLDWRNRFPNIIKELEQYSADIMCLQEVQEDHYKQQIKPSLESLGYHCEFKRRTGLKPDGCAVIFKRERFSLVS------------------CHPVEYFRRGVPLMDRDNVGLIVLLRPIDPHVSLSN---ICVANTHLLYNPRRGDIKLAQLAMLLAEISRV 367
BLAST of Endo/exonuclease/phosphatase domain-containing protein vs. Ensembl Zebrafish
Match: cnot6l (CCR4-NOT transcription complex, subunit 6-like [Source:NCBI gene;Acc:553665]) HSP 1 Score: 56.225 bits (134), Expect = 6.932e-8 Identity = 56/234 (23.93%), Postives = 96/234 (41.03%), Query Frame = 2
Query: 680 QQYPQMEYQKLNLFNPILSDKTFRICSYNILSHIYAETDKAKSVLYRHCNPEFLTRDYRQCLIFGELLQHKSDIIFLQEVDQSFYQKSLYPILQSYNYEGIFQKKSRT---------NWEGQAIFWNINKFKLIDNISIP-SLSMVINEENSEVYKKIKRFLRDTNLYNKWQSTGQCMTGCVLE------TVSL---ADRKRLMLCNNHLICDPKLEIFRLFQLAVGMLQLEQI 1324
+Q PQ + L + ++ F + YN+L YA LY +C L +YR+ I E+ +DII LQEV+ Y L+ Y+G F KSR + +G +F+ KF L+ ++ + + N E SEV + N+ + +LE L +++ L++ N H+ DP+ +L Q + + +L+ I
Sbjct: 162 EQLPQRPWITLRERDQMMPTAVFTVMCYNVLCDKYATRQ-----LYGYCPSWALNWEYRKKGIMEEITNCDADIISLQEVETEQYYTFFLETLKDRGYDGFFCPKSRAKLVSEQERKHVDGCGVFFKTEKFALVQKHTVEFNQVAMANSEGSEV------------MLNRVMTKDNIGVAVLLEVKKDLFAAGLKPPPEKQLLLVANAHMHWDPEYSDVKLIQTMMFLSELKSI 378
BLAST of Endo/exonuclease/phosphatase domain-containing protein vs. Ensembl Xenopus
Match: PDE12 (phosphodiesterase 12 [Source:HGNC Symbol;Acc:HGNC:25386]) HSP 1 Score: 127.102 bits (318), Expect = 1.042e-38 Identity = 89/340 (26.18%), Postives = 153/340 (45.00%), Query Frame = 2
Query: 365 LIKINEVIYQIYFKPPWIKTCKLPKITMVNIPITPILDLENVNESELSINWYVSKSSSSDDWIKCHTGTIFIPSENYLNFFIKLQ-VNSTLRNKNQNFQLISTSPIQQYPQ--MEYQKLNLFNPILSDKTFRICSYNILSHIYAETDKAKSVLYRHCNPEFLTRDYRQCLIFGELLQHKSDIIFLQEVDQSFYQKSLYPILQSYNYEGIFQKKSRTNWEGQAIFWNINKFKLIDNISIPSLSMVINE-ENSEVYKKIKRFLRDTNLYNKWQSTGQCMTGCVLETVSLADRKRLMLCNNHLICDPKLEIFRLFQLAVGMLQLEQIKYQ-YGEV----CCDW 1357
++++ Y + PP +LP++ +V P+ P L +E W W TG ++ P E L +KL+ V + ++ P + ++ L FR SYNIL+ +YA T+ ++ VLY +C L YR L+ EL +++DI+ LQE D+ ++ +L P+L+ EG ++ K R EG A F++ ++F+L+ I ++ E +SE+ ++ R+ K S Q + VLE++ R R+ + N HL PK RL Q+AV + L + + YG + C D+
Sbjct: 94 VLQVGAAQYLVERNPPAFLHLELPRVVLVGAPLCPRLCMEFGRPDLSRFEWL---RQGERGWEGAGTGRLYTPGEAELGLRLKLRAVPGDGTRWGCAAEAEPEGCVEAGPGRYLSDGRIVLTREGAGPGRFRTVSYNILAEVYARTELSREVLYPYCPAWALQGGYRHSLLRRELSGYRADILCLQEADREVFEAALGPLLEQLGMEGRYRGKERQQ-EGLATFYSRDRFRLLGQHDISLAGALLGEPRHSELLGRLSRYPGARERVLKRSSALQVL---VLESIEEPSR-RICVANTHLYFHPKGGHIRLVQMAVALAHLGHVANELYGGIPVVFCGDF 425 HSP 2 Score: 54.299 bits (129), Expect = 1.042e-38 Identity = 33/116 (28.45%), Postives = 62/116 (53.45%), Query Frame = 3
Query: 1347 VVIGGDFNASFDAELMRFILDKSV-----ECSLVNNAIKLNHSLGDFYSVFK--DKIEFTNFTPDYVGVLDHIVIDCSGLEVKHLYDVPNRLDIAKNISLPNEFHPSDHLPLLCDI 1673
VV GDFN+ + L RF+ ++ + + + N +L +S+ + +TN+ ++ G LD+I ID L ++ + +P+ ++ + +LP+ HPSDHL L+CD+
Sbjct: 419 VVFCGDFNSLPNTGLHRFVQGGAIAEDDEDWTSNGEEERCNMALTHPFSLASACGEPAYTNYIGEFHGCLDYIFIDSRQLALEQIIPLPSHEEVTQYRALPSVAHPSDHLALVCDL 534
BLAST of Endo/exonuclease/phosphatase domain-containing protein vs. Ensembl Xenopus
Match: hnf4g (hepatocyte nuclear factor 4 gamma [Source:Xenbase;Acc:XB-GENE-487527]) HSP 1 Score: 70.4774 bits (171), Expect = 3.306e-12 Identity = 62/233 (26.61%), Postives = 107/233 (45.92%), Query Frame = 2
Query: 662 ISTSPIQQYPQMEYQKLNLFNPILSDKTFRICSYNILSHIYAETDKAKSVLYRHCNPEFLTRDYRQCLIFGELLQHKSDIIFLQEVDQSFYQKSLYPILQSYNYEGIFQKKSRT---------NWEGQAIFWNINKFKLIDNISIP--SLSMVINEENSEVYKKIKRFLRDTNL-YNKWQSTGQCMTGCVLETVSLADRKRLMLCNNHLICDPKLEIFRLFQLAVGMLQLEQI 1324
+S P +Q PQ + L + IL +F + +N+L YA LY +C L +YR+ I E++ +DII LQEV+ Y P L+ Y+G F KSR + +G AIF+ KF L+ ++ ++M N E SE + R + N+ + ++G ++ ++++ LM+ N H+ DP+ +L Q + + +L+ I
Sbjct: 157 LSVHP-EQLPQRPWITLKERDQILPSVSFTVMCFNVLCDKYATRQ-----LYGYCPSWALNWEYRKKGIMEEIVSCDADIISLQEVETEQYYTLFMPALKERGYDGFFSPKSRAKIMSDQEKKHVDGCAIFFRTEKFSLVQKHTVEFNQIAMA-NSEGSEAM--LNRVMTKDNIGVTVLLELHKDLSGAGMKPHHSSEKQLLMVANAHMHWDPEYSDVKLIQTMMFVSELKSI 380
BLAST of Endo/exonuclease/phosphatase domain-containing protein vs. Ensembl Xenopus
Match: hnf4g (hepatocyte nuclear factor 4 gamma [Source:Xenbase;Acc:XB-GENE-487527]) HSP 1 Score: 70.4774 bits (171), Expect = 3.571e-12 Identity = 62/233 (26.61%), Postives = 107/233 (45.92%), Query Frame = 2
Query: 662 ISTSPIQQYPQMEYQKLNLFNPILSDKTFRICSYNILSHIYAETDKAKSVLYRHCNPEFLTRDYRQCLIFGELLQHKSDIIFLQEVDQSFYQKSLYPILQSYNYEGIFQKKSRT---------NWEGQAIFWNINKFKLIDNISIP--SLSMVINEENSEVYKKIKRFLRDTNL-YNKWQSTGQCMTGCVLETVSLADRKRLMLCNNHLICDPKLEIFRLFQLAVGMLQLEQI 1324
+S P +Q PQ + L + IL +F + +N+L YA LY +C L +YR+ I E++ +DII LQEV+ Y P L+ Y+G F KSR + +G AIF+ KF L+ ++ ++M N E SE + R + N+ + ++G ++ ++++ LM+ N H+ DP+ +L Q + + +L+ I
Sbjct: 157 LSVHP-EQLPQRPWITLKERDQILPSVSFTVMCFNVLCDKYATRQ-----LYGYCPSWALNWEYRKKGIMEEIVSCDADIISLQEVETEQYYTLFMPALKERGYDGFFSPKSRAKIMSDQEKKHVDGCAIFFRTEKFSLVQKHTVEFNQIAMA-NSEGSEAM--LNRVMTKDNIGVTVLLELHKDLSGAGMKPHHSSEKQLLMVANAHMHWDPEYSDVKLIQTMMFVSELKSI 380
BLAST of Endo/exonuclease/phosphatase domain-containing protein vs. Ensembl Xenopus
Match: hnf4g (hepatocyte nuclear factor 4 gamma [Source:Xenbase;Acc:XB-GENE-487527]) HSP 1 Score: 70.4774 bits (171), Expect = 3.913e-12 Identity = 62/233 (26.61%), Postives = 107/233 (45.92%), Query Frame = 2
Query: 662 ISTSPIQQYPQMEYQKLNLFNPILSDKTFRICSYNILSHIYAETDKAKSVLYRHCNPEFLTRDYRQCLIFGELLQHKSDIIFLQEVDQSFYQKSLYPILQSYNYEGIFQKKSRT---------NWEGQAIFWNINKFKLIDNISIP--SLSMVINEENSEVYKKIKRFLRDTNL-YNKWQSTGQCMTGCVLETVSLADRKRLMLCNNHLICDPKLEIFRLFQLAVGMLQLEQI 1324
+S P +Q PQ + L + IL +F + +N+L YA LY +C L +YR+ I E++ +DII LQEV+ Y P L+ Y+G F KSR + +G AIF+ KF L+ ++ ++M N E SE + R + N+ + ++G ++ ++++ LM+ N H+ DP+ +L Q + + +L+ I
Sbjct: 164 LSVHP-EQLPQRPWITLKERDQILPSVSFTVMCFNVLCDKYATRQ-----LYGYCPSWALNWEYRKKGIMEEIVSCDADIISLQEVETEQYYTLFMPALKERGYDGFFSPKSRAKIMSDQEKKHVDGCAIFFRTEKFSLVQKHTVEFNQIAMA-NSEGSEAM--LNRVMTKDNIGVTVLLELHKDLSGAGMKPHHSSEKQLLMVANAHMHWDPEYSDVKLIQTMMFVSELKSI 387
BLAST of Endo/exonuclease/phosphatase domain-containing protein vs. Ensembl Xenopus
Match: hnf4g (hepatocyte nuclear factor 4 gamma [Source:Xenbase;Acc:XB-GENE-487527]) HSP 1 Score: 66.2402 bits (160), Expect = 8.108e-11 Identity = 59/234 (25.21%), Postives = 105/234 (44.87%), Query Frame = 2
Query: 662 ISTSPIQQYPQMEYQKLNLFNPILSDKTFRICSYNILSHIYAETDKAKSVLYRHCNPEFLTRDYRQCLIFGELLQHKSDIIFLQEVDQSFYQKSLYPILQSYNYEGIFQKKSRT---------NWEGQAIFWNINKFKLIDNISIP--SLSMVINEENSEVYKKI--KRFLRDTNLYNKWQSTGQCMTGCVLETVSLADRKRLMLCNNHLICDPKLEIFRLFQLAVGMLQLEQI 1324
+S P +Q PQ + L + IL +F + +N+L YA LY +C L +YR+ I E++ +DII LQEV+ Y P L+ Y+G F KSR + +G AIF+ KF L+ ++ ++M +E + + ++ K + T L + ++ ++++ LM+ N H+ DP+ +L Q + + +L+ I
Sbjct: 157 LSVHP-EQLPQRPWITLKERDQILPSVSFTVMCFNVLCDKYATRQ-----LYGYCPSWALNWEYRKKGIMEEIVSCDADIISLQEVETEQYYTLFMPALKERGYDGFFSPKSRAKIMSDQEKKHVDGCAIFFRTEKFSLVQKHTVEFNQIAMANSEGSEAMLNRVMTKDNIGVTVLLELHKDLSGIFISIGMKPHHSSEKQLLMVANAHMHWDPEYSDVKLIQTMMFVSELKSI 384
BLAST of Endo/exonuclease/phosphatase domain-containing protein vs. Ensembl Mouse
Match: Pde12 (phosphodiesterase 12 [Source:MGI Symbol;Acc:MGI:2443226]) HSP 1 Score: 119.398 bits (298), Expect = 1.376e-37 Identity = 101/411 (24.57%), Postives = 189/411 (45.99%), Query Frame = 2
Query: 200 KMISKLYFSSNKRKNK---------KIKTEIPIDYCEIFALDIKNQNKICISDLTINDLLISNILIKINEVIYQIYFKPPWIKTCKLPKITMVNIPITPILDLENVNESELSINWYVSKSSSSDD-----------------WIKCHTGT---IFIPSENYLNFFIKLQVNSTLRNKNQNF----QLISTSPIQQYPQM-EYQKLNLFNPILSDKTF-RICSYNILSHIYAETDKAKSVLYRHCNPEFLTRDYRQCLIFGELLQHKSDIIFLQEVDQSFYQKSLYPILQSYNYEGIFQKKSRTNWEGQAIFWNINKFKLIDNISIPSLSMVINEENSEVYKK-IKRFLRDTNLYNKWQSTGQCMTGCVLETVSLADRKRLMLCNNHLICDPKLEIFRLFQLAVGMLQLEQI 1324
K +K+ + RKN+ + P+ CE + + + + D+ D +++I +V Y++ PP +LP+ M P+ P L +E + + WY + + WI+ TG ++ P + ++L+++ T N Q F +L S P++ P + +L+ +++ +F R SYNIL+ YA+T+ +++VLY +C P L DYRQ LI EL + +D+I LQEVD++ + SL P L+++ EG+F+ K EG A F+ +KF+L+ I S ++ ++K+ +++ + K + VL++ + + K++ + N HL PK RL Q+ V ++ + +
Sbjct: 83 KGHAKVAAAKKSRKNRAHSSGGAACEATGPEPVATCEPV-VKLYYREEAVAEDVLNVDAWQDGAVLQIGDVKYKVERNPPTFTELQLPRYIMAGFPVCPKLGVEFGDPASSVFRWYKEVKPGAAEPGDSGPASSSHSSQPSAWIE--TGVDERVYTPCN--ADIGLRLRLHCTPGN-GQRFGPSRELESLCPVEAGPGTCTFDHRHLYTKKVTEDSFIRTVSYNILADTYAQTEFSRTVLYPYCAPYALELDYRQNLIQKELTGYNADLICLQEVDRAVFSDSLVPALEAFGLEGVFRIKQH---EGLATFYRKSKFRLLSQHDI---SFQEALKSDPLHKELLEKLALNPLAQEKVLQRSSVLQISVLQSTTDSS-KKICVANTHLYWHPKGGYIRLIQMEVALVHIRHV 480 HSP 2 Score: 57.7658 bits (138), Expect = 1.376e-37 Identity = 34/124 (27.42%), Postives = 64/124 (51.61%), Query Frame = 3
Query: 1347 VVIGGDFNASFDAELMRFILDKSV--------------ECSL-VNNAIKLNHSLGDFYSVFKDKIEFTNFTPDYVGVLDHIVIDCSGLEVKHLYDVPNRLDIAKNISLPNEFHPSDHLPLLCDI 1673
V+ GDFN++ + F++ S+ CS+ +++ KL + G+ +TN+ + G LD+I ID + LEV+ + +P+ ++ + +LP+ HPSDH+ L+CD+
Sbjct: 490 VIFCGDFNSTPSTGMYHFVISGSIAEDHEDWASNGEEERCSMPLSHCFKLKSACGE--------PAYTNYVGGFHGCLDYIFIDLNTLEVEQVIPLPSHEEVTTHQALPSVSHPSDHIALVCDL 605
BLAST of Endo/exonuclease/phosphatase domain-containing protein vs. Ensembl Mouse
Match: Pde12 (phosphodiesterase 12 [Source:MGI Symbol;Acc:MGI:2443226]) HSP 1 Score: 119.398 bits (298), Expect = 1.376e-37 Identity = 101/411 (24.57%), Postives = 189/411 (45.99%), Query Frame = 2
Query: 200 KMISKLYFSSNKRKNK---------KIKTEIPIDYCEIFALDIKNQNKICISDLTINDLLISNILIKINEVIYQIYFKPPWIKTCKLPKITMVNIPITPILDLENVNESELSINWYVSKSSSSDD-----------------WIKCHTGT---IFIPSENYLNFFIKLQVNSTLRNKNQNF----QLISTSPIQQYPQM-EYQKLNLFNPILSDKTF-RICSYNILSHIYAETDKAKSVLYRHCNPEFLTRDYRQCLIFGELLQHKSDIIFLQEVDQSFYQKSLYPILQSYNYEGIFQKKSRTNWEGQAIFWNINKFKLIDNISIPSLSMVINEENSEVYKK-IKRFLRDTNLYNKWQSTGQCMTGCVLETVSLADRKRLMLCNNHLICDPKLEIFRLFQLAVGMLQLEQI 1324
K +K+ + RKN+ + P+ CE + + + + D+ D +++I +V Y++ PP +LP+ M P+ P L +E + + WY + + WI+ TG ++ P + ++L+++ T N Q F +L S P++ P + +L+ +++ +F R SYNIL+ YA+T+ +++VLY +C P L DYRQ LI EL + +D+I LQEVD++ + SL P L+++ EG+F+ K EG A F+ +KF+L+ I S ++ ++K+ +++ + K + VL++ + + K++ + N HL PK RL Q+ V ++ + +
Sbjct: 83 KGHAKVAAAKKSRKNRAHSSGGAACEATGPEPVATCEPV-VKLYYREEAVAEDVLNVDAWQDGAVLQIGDVKYKVERNPPTFTELQLPRYIMAGFPVCPKLGVEFGDPASSVFRWYKEVKPGAAEPGDSGPASSSHSSQPSAWIE--TGVDERVYTPCN--ADIGLRLRLHCTPGN-GQRFGPSRELESLCPVEAGPGTCTFDHRHLYTKKVTEDSFIRTVSYNILADTYAQTEFSRTVLYPYCAPYALELDYRQNLIQKELTGYNADLICLQEVDRAVFSDSLVPALEAFGLEGVFRIKQH---EGLATFYRKSKFRLLSQHDI---SFQEALKSDPLHKELLEKLALNPLAQEKVLQRSSVLQISVLQSTTDSS-KKICVANTHLYWHPKGGYIRLIQMEVALVHIRHV 480 HSP 2 Score: 57.7658 bits (138), Expect = 1.376e-37 Identity = 34/124 (27.42%), Postives = 64/124 (51.61%), Query Frame = 3
Query: 1347 VVIGGDFNASFDAELMRFILDKSV--------------ECSL-VNNAIKLNHSLGDFYSVFKDKIEFTNFTPDYVGVLDHIVIDCSGLEVKHLYDVPNRLDIAKNISLPNEFHPSDHLPLLCDI 1673
V+ GDFN++ + F++ S+ CS+ +++ KL + G+ +TN+ + G LD+I ID + LEV+ + +P+ ++ + +LP+ HPSDH+ L+CD+
Sbjct: 490 VIFCGDFNSTPSTGMYHFVISGSIAEDHEDWASNGEEERCSMPLSHCFKLKSACGE--------PAYTNYVGGFHGCLDYIFIDLNTLEVEQVIPLPSHEEVTTHQALPSVSHPSDHIALVCDL 605
BLAST of Endo/exonuclease/phosphatase domain-containing protein vs. Ensembl Mouse
Match: Cnot6l (CCR4-NOT transcription complex, subunit 6-like [Source:MGI Symbol;Acc:MGI:2443154]) HSP 1 Score: 69.707 bits (169), Expect = 3.882e-12 Identity = 62/228 (27.19%), Postives = 103/228 (45.18%), Query Frame = 2
Query: 650 NFQL--ISTSPIQQYPQMEYQKLNLFNPILSDKTFRICSYNILSHIYAETDKAKSVLYRHCNPEFLTRDYRQCLIFGELLQHKSDIIFLQEVDQSFYQKSLYPILQSYNYEGIFQKKSRT---------NWEGQAIFWNINKFKLIDNISIP--SLSMVINEENSEVYKKIKRFLRDTNL-YNKWQSTGQCMTGCVLETVSLADRKRLMLCNNHLICDPKLEIFRLFQ 1291
NF L ++ P +Q P + L + IL +F + YN+L YA LY +C L +YR+ I E++ +DII LQEV+ Y P L+ Y+G F KSR + +G AIF+ KF L+ ++ ++M N + SE + R + N+ + + G ++ + AD++ L++ N H+ DP+ +L Q
Sbjct: 151 NFMLDNLAVHP-EQLPPRPWITLKERDQILPSASFTVMCYNVLCDKYATRQ-----LYGYCPSWALNWEYRKKGIMEEIVNWDADIISLQEVETEQYFTLFLPALKDRGYDGFFSPKSRAKIMSEQERKHVDGCAIFFKTEKFTLVQKHTVEFNQVAMA-NSDGSEAM--LNRVMTKDNIGVAVVLEVHKELFGTGMKPIHAADKQLLIVANAHMHWDPEYSDVKLIQ 369
BLAST of Endo/exonuclease/phosphatase domain-containing protein vs. Ensembl Mouse
Match: Cnot6l (CCR4-NOT transcription complex, subunit 6-like [Source:MGI Symbol;Acc:MGI:2443154]) HSP 1 Score: 69.3218 bits (168), Expect = 7.134e-12 Identity = 61/227 (26.87%), Postives = 102/227 (44.93%), Query Frame = 2
Query: 650 NFQL--ISTSPIQQYPQMEYQKLNLFNPILSDKTFRICSYNILSHIYAETDKAKSVLYRHCNPEFLTRDYRQCLIFGELLQHKSDIIFLQEVDQSFYQKSLYPILQSYNYEGIFQKKSRT---------NWEGQAIFWNINKFKLIDNISIP-SLSMVINEENSEVYKKIKRFLRDTNL-YNKWQSTGQCMTGCVLETVSLADRKRLMLCNNHLICDPKLEIFRLFQ 1291
NF L ++ P +Q P + L + IL +F + YN+L YA LY +C L +YR+ I E++ +DII LQEV+ Y P L+ Y+G F KSR + +G AIF+ KF L+ ++ + + N + SE + R + N+ + + G ++ + AD++ L++ N H+ DP+ +L Q
Sbjct: 151 NFMLDNLAVHP-EQLPPRPWITLKERDQILPSASFTVMCYNVLCDKYATRQ-----LYGYCPSWALNWEYRKKGIMEEIVNWDADIISLQEVETEQYFTLFLPALKDRGYDGFFSPKSRAKIMSEQERKHVDGCAIFFKTEKFTLVQKHTVEFNQVAMANSDGSEAM--LNRVMTKDNIGVAVVLEVHKELFGTGMKPIHAADKQLLIVANAHMHWDPEYSDVKLIQ 369
BLAST of Endo/exonuclease/phosphatase domain-containing protein vs. Ensembl Mouse
Match: Cnot6l (CCR4-NOT transcription complex, subunit 6-like [Source:MGI Symbol;Acc:MGI:2443154]) HSP 1 Score: 68.9366 bits (167), Expect = 7.517e-12 Identity = 61/227 (26.87%), Postives = 102/227 (44.93%), Query Frame = 2
Query: 650 NFQL--ISTSPIQQYPQMEYQKLNLFNPILSDKTFRICSYNILSHIYAETDKAKSVLYRHCNPEFLTRDYRQCLIFGELLQHKSDIIFLQEVDQSFYQKSLYPILQSYNYEGIFQKKSRT---------NWEGQAIFWNINKFKLIDNISIP-SLSMVINEENSEVYKKIKRFLRDTNL-YNKWQSTGQCMTGCVLETVSLADRKRLMLCNNHLICDPKLEIFRLFQ 1291
NF L ++ P +Q P + L + IL +F + YN+L YA LY +C L +YR+ I E++ +DII LQEV+ Y P L+ Y+G F KSR + +G AIF+ KF L+ ++ + + N + SE + R + N+ + + G ++ + AD++ L++ N H+ DP+ +L Q
Sbjct: 156 NFMLDNLAVHP-EQLPPRPWITLKERDQILPSASFTVMCYNVLCDKYATRQ-----LYGYCPSWALNWEYRKKGIMEEIVNWDADIISLQEVETEQYFTLFLPALKDRGYDGFFSPKSRAKIMSEQERKHVDGCAIFFKTEKFTLVQKHTVEFNQVAMANSDGSEAM--LNRVMTKDNIGVAVVLEVHKELFGTGMKPIHAADKQLLIVANAHMHWDPEYSDVKLIQ 374
BLAST of Endo/exonuclease/phosphatase domain-containing protein vs. UniProt/SwissProt
Match: sp|Q3TIU4|PDE12_MOUSE (2',5'-phosphodiesterase 12 OS=Mus musculus OX=10090 GN=Pde12 PE=1 SV=2) HSP 1 Score: 119.398 bits (298), Expect = 8.367e-37 Identity = 101/411 (24.57%), Postives = 189/411 (45.99%), Query Frame = 2
Query: 200 KMISKLYFSSNKRKNK---------KIKTEIPIDYCEIFALDIKNQNKICISDLTINDLLISNILIKINEVIYQIYFKPPWIKTCKLPKITMVNIPITPILDLENVNESELSINWYVSKSSSSDD-----------------WIKCHTGT---IFIPSENYLNFFIKLQVNSTLRNKNQNF----QLISTSPIQQYPQM-EYQKLNLFNPILSDKTF-RICSYNILSHIYAETDKAKSVLYRHCNPEFLTRDYRQCLIFGELLQHKSDIIFLQEVDQSFYQKSLYPILQSYNYEGIFQKKSRTNWEGQAIFWNINKFKLIDNISIPSLSMVINEENSEVYKK-IKRFLRDTNLYNKWQSTGQCMTGCVLETVSLADRKRLMLCNNHLICDPKLEIFRLFQLAVGMLQLEQI 1324
K +K+ + RKN+ + P+ CE + + + + D+ D +++I +V Y++ PP +LP+ M P+ P L +E + + WY + + WI+ TG ++ P + ++L+++ T N Q F +L S P++ P + +L+ +++ +F R SYNIL+ YA+T+ +++VLY +C P L DYRQ LI EL + +D+I LQEVD++ + SL P L+++ EG+F+ K EG A F+ +KF+L+ I S ++ ++K+ +++ + K + VL++ + + K++ + N HL PK RL Q+ V ++ + +
Sbjct: 83 KGHAKVAAAKKSRKNRAHSSGGAACEATGPEPVATCEPV-VKLYYREEAVAEDVLNVDAWQDGAVLQIGDVKYKVERNPPTFTELQLPRYIMAGFPVCPKLGVEFGDPASSVFRWYKEVKPGAAEPGDSGPASSSHSSQPSAWIE--TGVDERVYTPCN--ADIGLRLRLHCTPGN-GQRFGPSRELESLCPVEAGPGTCTFDHRHLYTKKVTEDSFIRTVSYNILADTYAQTEFSRTVLYPYCAPYALELDYRQNLIQKELTGYNADLICLQEVDRAVFSDSLVPALEAFGLEGVFRIKQH---EGLATFYRKSKFRLLSQHDI---SFQEALKSDPLHKELLEKLALNPLAQEKVLQRSSVLQISVLQSTTDSS-KKICVANTHLYWHPKGGYIRLIQMEVALVHIRHV 480 HSP 2 Score: 57.7658 bits (138), Expect = 8.367e-37 Identity = 34/124 (27.42%), Postives = 64/124 (51.61%), Query Frame = 3
Query: 1347 VVIGGDFNASFDAELMRFILDKSV--------------ECSL-VNNAIKLNHSLGDFYSVFKDKIEFTNFTPDYVGVLDHIVIDCSGLEVKHLYDVPNRLDIAKNISLPNEFHPSDHLPLLCDI 1673
V+ GDFN++ + F++ S+ CS+ +++ KL + G+ +TN+ + G LD+I ID + LEV+ + +P+ ++ + +LP+ HPSDH+ L+CD+
Sbjct: 490 VIFCGDFNSTPSTGMYHFVISGSIAEDHEDWASNGEEERCSMPLSHCFKLKSACGE--------PAYTNYVGGFHGCLDYIFIDLNTLEVEQVIPLPSHEEVTTHQALPSVSHPSDHIALVCDL 605
BLAST of Endo/exonuclease/phosphatase domain-containing protein vs. UniProt/SwissProt
Match: sp|Q6L8Q7|PDE12_HUMAN (2',5'-phosphodiesterase 12 OS=Homo sapiens OX=9606 GN=PDE12 PE=1 SV=2) HSP 1 Score: 123.635 bits (309), Expect = 1.596e-28 Identity = 99/396 (25.00%), Postives = 174/396 (43.94%), Query Frame = 2
Query: 266 PIDYCEIFALDIKNQNKICISDLTINDLLISNILIKINEVIYQIYFKPPWIKTCKLPKITMVNIPITPILDLENVNESELSINWYVSKSSSSDD-----------------WIKCHTGT-IFIPSENYLNFFIKLQVNSTLRNK-NQNFQLISTSPIQQYPQM-EYQKLNLFNP-ILSDKTFRICSYNILSHIYAETDKAKSVLYRHCNPEFLTRDYRQCLIFGELLQHKSDIIFLQEVDQSFYQKSLYPILQSYNYEGIFQKKSRTNWEGQAIFWNINKFKLIDNISIPSLSMVINEENSEVYKK-IKRFLRDTNLYNKWQSTGQCMTGCVLETVSLADRKRLMLCNNHLICDPKLEIFRLFQLAVGMLQLEQIKYQYGEVCCDWWRFQCIV*CG 1387
P +CE + + + + D+ D +++I +V Y++ PP +LP+ M P+ P L LE + + WY + + W + ++ PS + +KL + + +L S ++ P + +L+ + D R SYNIL+ YA+T+ +++VLY +C P L DYRQ LI EL + +D+I LQEVD++ + SL P L+++ EG+F+ K EG A F+ +KF L+ I S E+ ++K+ +++ + + K + VL++ + KR+ + N HL PK RL Q+AV + + V CD + ++ CG
Sbjct: 115 PAVFCEPV-VKLYYREEAVAEDVLNVDAWQDGAVLQIGDVKYKVERNPPAFTELQLPRYIMAGFPVCPKLSLEFGDPASSLFRWYKEAKPGAAEPEVGVPSSLSPSSPSSSWTETDVEERVYTPSNADIGLRLKLHCTPGDGQRFGHSRELESVCVVEAGPGTCTFDHRHLYTKKVTEDALIRTVSYNILADTYAQTEFSRTVLYPYCAPYALELDYRQNLIQKELTGYNADVICLQEVDRAVFSDSLVPALEAFGLEGVFRIKQH---EGLATFYRKSKFSLLSQHDI---SFYEALESDPLHKELLEKLVLYPSAQEKVLQRSSVLQVSVLQSTKDSS-KRICVANTHLYWHPKGGYIRLIQMAVALAHIRH-------VSCDLYPGIPVIFCG 495 HSP 2 Score: 59.6918 bits (143), Expect = 4.402e-8 Identity = 34/116 (29.31%), Postives = 64/116 (55.17%), Query Frame = 3
Query: 1347 VVIGGDFNASFDAELMRFILDKSV-----ECSLVNNAIKLNHSLGDFYSVFKDKIE--FTNFTPDYVGVLDHIVIDCSGLEVKHLYDVPNRLDIAKNISLPNEFHPSDHLPLLCDI 1673
V+ GDFN++ + F+++ S+ + + + N SL F+ + E +TN+ + G LD+I ID + LEV+ + +P+ ++ + +LP+ HPSDH+ L+CD+
Sbjct: 491 VIFCGDFNSTPSTGMYHFVINGSIPEDHEDWASNGEEERCNMSLTHFFKLKSACGEPAYTNYVGGFHGCLDYIFIDLNALEVEQVIPLPSHEEVTTHQALPSVSHPSDHIALVCDL 606
BLAST of Endo/exonuclease/phosphatase domain-containing protein vs. UniProt/SwissProt
Match: sp|Q6AXQ5|PDE12_RAT (2',5'-phosphodiesterase 12 OS=Rattus norvegicus OX=10116 GN=Pde12 PE=2 SV=1) HSP 1 Score: 123.635 bits (309), Expect = 1.617e-28 Identity = 97/375 (25.87%), Postives = 171/375 (45.60%), Query Frame = 2
Query: 344 DLLISNILIKINEVIYQIYFKPPWIKTCKLPKITMVNIPITPILDLENVNESELSINWYVSKSSSSDD-----------------WIKCHTGT---IFIPSENYLNFFIKLQVNSTLRNKNQNF----QLISTSPIQQYPQM-EYQKLNLFNPILSDKTF-RICSYNILSHIYAETDKAKSVLYRHCNPEFLTRDYRQCLIFGELLQHKSDIIFLQEVDQSFYQKSLYPILQSYNYEGIFQKKSRTNWEGQAIFWNINKFKLIDNISIPSLSMVINEENSEVYKK-IKRFLRDTNLYNKWQSTGQCMTGCVLETVSLADRKRLMLCNNHLICDPKLEIFRLFQLAVGMLQLEQIKYQYGEVCCDWWRFQCIV*CG 1387
D +++I +V Y++ PP +LP+ M P+ P L LE + + WY + + WI+ TG ++ P + +KL Q F +L S P++ P + +L+ +++ +F R SYNIL+ YA+T+ +++VLY +C P L DYRQ LI EL + +D+I LQEVD++ + SL P L+++ EG+F+ K EG A F+ +KF+L+ I S ++ ++K+ +++ + K + VL++ + + K++ + N HL PK RL Q+A ++ + V CD + ++ CG
Sbjct: 139 DAWQDGAVLQIGDVKYKVERNPPAFTELQLPRYIMAGFPVCPKLGLEFGDPASSVFRWYKEVKPGAAEPGDSGLASSSHSLQSSAWIE--TGVDERVYTPCNADIGLRLKLHCTP---GNGQRFGPSRELESVCPVEAGPGTCTFDHRHLYTKKVTEDSFIRTVSYNILADTYAQTEFSRTVLYPYCAPYALELDYRQNLIQKELTGYNADLICLQEVDRAVFSDSLVPALEAFGLEGVFRIKQH---EGLATFYRKSKFRLLSQHDI---SFQEALKSDPLHKELLEKLALNPLAQEKVLQRSSVLQISVLQSTTDSS-KKICVANTHLYWHPKGGYIRLIQMAAALVHIRH-------VSCDLYPGIPVIFCG 494 HSP 2 Score: 57.7658 bits (138), Expect = 2.002e-7 Identity = 34/124 (27.42%), Postives = 63/124 (50.81%), Query Frame = 3
Query: 1347 VVIGGDFNASFDAELMRFILDKSV--------------ECSL-VNNAIKLNHSLGDFYSVFKDKIEFTNFTPDYVGVLDHIVIDCSGLEVKHLYDVPNRLDIAKNISLPNEFHPSDHLPLLCDI 1673
V+ GDFN++ + F+++ SV C + + + KL + G+ +TN+ + G LD+I ID + LEV+ + +P+ ++ + +LP+ HPSDH+ L+CD+
Sbjct: 490 VIFCGDFNSTPSTGMYHFVINGSVPEDHEDWASNGEEERCGMSLTHCFKLKSACGE--------PAYTNYVGGFHGCLDYIFIDLNALEVEQVIPLPSHEEVTTHQALPSVSHPSDHIALVCDL 605
BLAST of Endo/exonuclease/phosphatase domain-containing protein vs. UniProt/SwissProt
Match: sp|Q08DF7|PDE12_BOVIN (2',5'-phosphodiesterase 12 OS=Bos taurus OX=9913 GN=PDE12 PE=1 SV=1) HSP 1 Score: 121.324 bits (303), Expect = 9.508e-28 Identity = 101/377 (26.79%), Postives = 166/377 (44.03%), Query Frame = 2
Query: 344 DLLISNILIKINEVIYQIYFKPPWIKTCKLPKITMVNIPITPILDLENVNESELSINWYVSKSSSSDD-----------------WIKCHTGT---IFIPSENYLNFFIKLQVNSTLRNKNQNF----QLISTSPIQQYPQM-EYQKLNLFNPILSDKTF-RICSYNILSHIYAETDKAKSVLYRHCNPEFLTRDYRQCLIFGELLQHKSDIIFLQEVDQSFYQKSLYPILQSYNYEGIFQKKSRTNWEGQAIFWNINKFKLIDNISIPSLSMVINEENSEVYKKIKRFLRDTNLYNKWQSTGQCMTGCVLETV--SLAD-RKRLMLCNNHLICDPKLEIFRLFQLAVGMLQLEQIKYQYGEVCCDWWRFQCIV*CG 1387
D +++I +V Y++ PP +LP+ M P+ P L +E + + WY + + W + TG ++ PS + +KL Q F +L S P++ P + +L+ ++D R SYNIL+ YA+T+ +++VLY +C P L DYRQ LI EL + +D+I LQEVD+ + SL P L+++ EG+F+ K EG A F+ +KF L+ I + ++ ++K++ L LY Q + V +V S D K++ + N HL PK RL Q+AV + + V CD + ++ CG
Sbjct: 140 DAWQDGAVLQIGDVKYKVERNPPAFTELQLPRYIMAGFPVCPKLGVEFGDPTGSLFRWYKETKPRAAEPEGGGPSSSSPSSPSPGWTE--TGVDERVYTPSNADIGLRLKLHCTP---GNGQRFGPSRELESVCPVEAGPGTCTFDHRHLYTKKVTDDALIRTVSYNILADTYAQTEFSRTVLYPYCAPYALELDYRQNLIQKELTGYNADLICLQEVDRCVFTDSLMPALEAFGLEGVFRIKQH---EGLATFYRKSKFSLLSQHDIAFHEAL---QSDPLHKEL---LEKLALYPSAQERVLQRSSVVQVSVLQSTKDSSKKICVANTHLYWHPKGGYIRLIQMAVALAHIRH-------VSCDLYPGIPVIFCG 495 HSP 2 Score: 59.6918 bits (143), Expect = 4.558e-8 Identity = 34/116 (29.31%), Postives = 63/116 (54.31%), Query Frame = 3
Query: 1347 VVIGGDFNASFDAELMRFILDKSV-----ECSLVNNAIKLNHSLGDFYSVFKDKIE--FTNFTPDYVGVLDHIVIDCSGLEVKHLYDVPNRLDIAKNISLPNEFHPSDHLPLLCDI 1673
V+ GDFN++ + F+++ S+ + + + N SL F+ + E +TN+ + G LD+I ID LEV+ + +P+ ++ + +LP+ HPSDH+ L+CD+
Sbjct: 491 VIFCGDFNSTPSTGMYHFVINGSIAEDHEDWTSNGEEERCNMSLSHFFKLKSACGEPAYTNYVGGFHGCLDYIFIDLHALEVEQVIPLPSHEEVTTHQALPSVSHPSDHIALVCDL 606
BLAST of Endo/exonuclease/phosphatase domain-containing protein vs. UniProt/SwissProt
Match: sp|P31384|CCR4_YEAST (Glucose-repressible alcohol dehydrogenase transcriptional effector OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=CCR4 PE=1 SV=2) HSP 1 Score: 73.1738 bits (178), Expect = 1.243e-20 Identity = 62/225 (27.56%), Postives = 101/225 (44.89%), Query Frame = 2
Query: 689 PQMEY----QKLNLFNPILSDKTFRICSYNILSHIYAETDKAKSVLYRHCNPEFLTRDYRQCLIFGELLQHKSDIIFLQEVDQSFYQKSLYPILQSYNYEGIFQKKSRTNW---------EGQAIFWNINKFKLIDNISIPSLSMVINEENSEVYKKIKRFLRDTNLYNKWQSTGQCMTGCVLETVSLADRKRLMLCNNHLICDPKLEIFRLFQLAVGMLQLEQI 1324
PQ EY Q L+ +TF + SYN L YA T K +YR+ L+ DYR+ + ++L + SD++ LQEV+ +++ P+L + Y GIF K+R +G IF+ ++FKLI ++ + S + K K+F R + N+ + L+ + D + HL DPK + FQ+ V + LE +
Sbjct: 482 PQREYDSLQQSTEHLATDLAKRTFTVLSYNTLCQHYA-TPK----MYRYTPSWALSWDYRRNKLKEQILSYDSDLLCLQEVESKTFEEYWVPLLDKHGYTGIFHAKARAKTMHSKDSKKVDGCCIFFKRDQFKLITKDAM---------DFSGAWMKHKKFQRTEDYLNRAMNKDNVALFLKLQHIPSGD--TIWAVTTHLHWDPKFNDVKTFQVGVLLDHLETL 690 HSP 2 Score: 49.6766 bits (117), Expect = 1.243e-20 Identity = 35/117 (29.91%), Postives = 54/117 (46.15%), Query Frame = 3
Query: 1347 VVIGGDFNASFDAELMRFILDKSVECSLVNNAIKL----------NHSLGDFYSVFKDKIEFTNFTPDYVGVLDHIVIDCSGLEVKHLYDVPNRLDIAKNISLPNEFHPSDHLPLLC 1667
V+I GDFN+ ++ + I V+ N N +L Y+ + + FTNFTP + V+D+I L V+ L + ++K I PN+ PSDH+PLL
Sbjct: 708 VLICGDFNSYINSAVYELINTGRVQIHQEGNGRDFGYMSEKNFSHNLALKSSYNCIGE-LPFTNFTPSFTDVIDYIWFSTHALRVRGLLGEVDPEYVSKFIGFPNDKFPSDHIPLLA 823
BLAST of Endo/exonuclease/phosphatase domain-containing protein vs. TrEMBL
Match: A0A5A9NBT1 (2',5'-phosphodiesterase 12 OS=Triplophysa tibetana OX=1572043 GN=E1301_Tti021121 PE=4 SV=1) HSP 1 Score: 151.754 bits (382), Expect = 6.779e-42 Identity = 115/409 (28.12%), Postives = 208/409 (50.86%), Query Frame = 2
Query: 158 FLRPISESLEVLFNKMISKLYFSSNK-RKNKKIKTEIPIDYCEIFALDIKNQNKICIS------DLTINDLLISNILIKINEVIYQIYFKPPWIKTCKLPKITMVNIPITPILDLENVNESELSINWY--VSKSSSS----DDWIKCHTGTIFIPSENYLNFFIKLQVNSTLRNK---NQNFQLISTSPIQQYPQM-EYQKLNLFNPILSDKT-FRICSYNILSHIYAETDKAKSVLYRHCNPEFLTRDYRQCLIFGELLQHKSDIIFLQEVDQSFYQKSLYPILQSYNYEGIFQKKSRTNWEGQAIFWNINKFKLIDNISIP-SLSMVINEENSEVYKKIKRFLRDTNLYNKWQSTGQCMTGCVLETVSLADRKRLM-LCNNHLICDPKLEIFRLFQLAVGMLQLEQI 1324
LR +E LE + +M + + + +K +K+K+ + E ++ EI K+C++ D +D ++ + E+ Y++ PP +LP + + P+ P L++E + + W+ +S +S S D W + +F PS L+ +K+ + T RN + +L+S ++ P + +++ ++D+T RI SYNIL+ IYA+TD +K+VLY +C P L DYR LI EL + +DII LQEVD+ + SL P L ++ +G+F+ K R + EG A F+ +KFK++ + S +++ + + E+ K+ +++L K + + VL+ SL D R++ + N HL P RL Q+AV + ++Q+
Sbjct: 63 MLREQTEPLEKVLTRMSNSIIKAQSKDKKSKRCRGETAVEKPEI---------KLCVNGEPVTLDTANSDAWKDGAVLHVGEMTYKVERNPPTFTVSELPSSLLSDFPVCPKLEVEFGDVKDGEFRWFKEISPNSHSSGEQDCWREAGDERVFTPSN--LDIGLKVMLKCTPRNGSRFGEPAKLVSAGTVEAGPGTCTFDNRHMYTQRVTDETSVRIVSYNILADIYAQTDLSKTVLYPYCPPYALEMDYRHNLIKKELSGYNADIICLQEVDKGAFTDSLSPALDAFGLDGVFKIKERQH-EGLATFFRRSKFKMLGQYDVTLSKALMTDPLHQELLDKVS---TNSSLREKIVNRSTALQVTVLQ--SLCDPSRVICVGNTHLYWHPTGGNVRLVQIAVALKHMKQV 454 HSP 2 Score: 50.0618 bits (118), Expect = 6.779e-42 Identity = 34/126 (26.98%), Postives = 64/126 (50.79%), Query Frame = 3
Query: 1344 CVVIGGDFNASFDAELMRFILDKSV----------------ECSLVNNAIKLNHSLGDFYSVFKDKIEFTNFTPDYVGVLDHIVIDCSGLEVKHLYDVPNRLDIAKNISLPNEFHPSDHLPLLCDI 1673
C++ GDFN++ + L++ + S+ + SLVN ++L + G + V+ TN+ + G LD+I ++ L+V + +P+ +I +LP+ HPSDH+ L+CD+
Sbjct: 463 CLMFSGDFNSTPTSGLLQLMCQGSILENHEDWASSGPEELLQMSLVN-PLQLVSACG--FPVY------TNYVGGFQGCLDYIFVEPHVLQVDQIIPLPSHQEITTCQALPSVSHPSDHIALVCDL 579
BLAST of Endo/exonuclease/phosphatase domain-containing protein vs. TrEMBL
Match: A0A4Y2B8A3 (2',5'-phosphodiesterase 12 OS=Araneus ventricosus OX=182803 GN=Pde12_0 PE=4 SV=1) HSP 1 Score: 144.05 bits (362), Expect = 1.161e-41 Identity = 124/454 (27.31%), Postives = 218/454 (48.02%), Query Frame = 2
Query: 53 NQLNHIFIRNSDQINNHVLIEFEYSFENSSSLYYSFLRPISESLEVLFNKM----ISKLYFSSNKRKNKKIKTEIPIDYCEI-FALDIKNQNKICISDLTINDLLISNILIKINEVIYQIYFKPPWIKTCKLPKITMVNIPITPILDLENVNESELSINWY--VSK------------SSSSDDWIKCHTGTIFIPSENYLNFFIKLQVNSTLRNKNQ---NFQLISTSPIQQYPQ---MEYQKLNLFNPILSDKTFRICSYNILSHIYAETDKAKSVLYRHCNPEFLTRDYRQCLIFGELLQHKSDIIFLQEVDQSFYQKSLYPILQSYNYEGIFQKKSRTNWEGQAIFWNINKFKLIDNISIPSLSMVINEENSEVYKKIK-RFLRDTNLYNKWQSTGQCMTGCVLETVSLADRKRLMLCNNHLICDPKLEIFRLFQLAVGMLQLEQIKYQY 1336
+Q +F+++ + N + I F +F + ++FLR E LEV ++M + N +K KKI + + +I L I + ++L D N +KIN+ +Y+I PP + LPK M P+ P ++LE + + WY +SK S+ S++W+ +I +E + KL+V+ +N + +STS IQ P+ EY+ N I R SYNIL+ +YA+++ A++ L+ +C EFL DYR+ L E++ + +DII LQEVD+ + L P+L S +GI+ +K EG ++F+ +KF+++++ + V NE V K I+ + + L ++ S + +LE+ + +KR+++ N HL P + RL Q ++ LE + +Y
Sbjct: 2 SQCAKVFVKHIED-ENKMKIYFNLAFPDLPERTFTFLRSKEEKLEVTISRMKLKILEAFNKKLNNKKKKKISETVDENNTQISLTLAILKDGEFIDNELRNIDAWTENAQLKINDHVYEIAENPPSVLHLSLPKSIMSGFPVYPKVELEYCFKEQCDFTWYRTISKAEKSTVDINKIVSTKSENWLILSKNYFYITNET--DVGCKLKVSCVPKNGEKVGLEEIAVSTSLIQAGPEKCPFEYRH-EFTNSITEPGMLRCVSYNILADLYADSETARTELFPYCPVEFLMLDYRRQLYLKEIMGYNADIICLQEVDRKVFYGDLVPVLTSTGLDGIYSEKGGQVVEGLSLFYRTSKFRVVESQAKILSDAVTNE---PVLKPIQDKLAENEKLKERFMSRTTAVQAVLLESTDVP-QKRILVGNTHLYFRPDRDNIRLLQATSCIMYLEDLLLKY 447 HSP 2 Score: 56.9954 bits (136), Expect = 1.161e-41 Identity = 38/130 (29.23%), Postives = 65/130 (50.00%), Query Frame = 3
Query: 1311 NWSRLNTNTVKCVVIGGDFNASFDAELMRFI---------LDKSVECSLVNNAIKLNHSLGDFYSVFKDKIEFTNFTPDYVGVLDHIVIDCSGLEVKHLYDVPNRLDIAKNISLPNEFHPSDHLPLLCDI 1673
+ + N + V +++ GDFN+ + + +FI +D + I L HSL + +TN+T +VG LD+I + + LEVK + +P+ + K +LPN+ PSDHL L+C +
Sbjct: 446 KYQKENPSYVTSLMLCGDFNSCPENGVYKFITEGYLNEDCIDWQSNPEEIVPGIPLKHSLSIDSAC--GTPSYTNYTEGFVGCLDYIFYNKAHLEVKDVVPLPHHEQVTKYKALPNKVFPSDHLALVCTL 573
BLAST of Endo/exonuclease/phosphatase domain-containing protein vs. TrEMBL
Match: T1HYV8 (Endo/exonuclease/phosphatase domain-containing protein (Fragment) OS=Rhodnius prolixus OX=13249 PE=4 SV=1) HSP 1 Score: 153.68 bits (387), Expect = 3.383e-41 Identity = 98/330 (29.70%), Postives = 177/330 (53.64%), Query Frame = 2
Query: 353 ISNILIKINEVIYQIYFKPPWIKTCKLPKITMVNIPITPILDLENVNESELSINWYVSKSSSSDDWIKCHTGTIFIPSENYLNFFIKL---QVNSTLRNKNQNFQLISTSPIQQYPQM-EYQKLNLFN-PILSDKTFRICSYNILSHIYAETDKAKSVLYRHCNPEFLTRDYRQCLIFGELLQHKSDIIFLQEVDQSFYQKSLYPILQSYNYEGIFQKKSRTNWEGQAIFWNINKFKLIDNI-SIPSLSMVINEENSEVYKKIKRFLRDTNLYNKWQSTGQCMTGCVLETVSLADRKRLMLCNNHLICDPKLEIFRLFQLAVGMLQLEQI 1324
++ + +K+++ Y + PWI LP M P+ PI+D++ N+ + + WY + SSS+DWI+ TG ++IPS + ++ +KL N T + ++ ++ P + +Q+ LF IL + FR+ SYNIL+ +YAETD AK+ L+ +C P L+ DYR+ L E++ + +DI+ LQEVD + L +L + +G+ +K + EG A F++ KF+L++ + S + +N ++ KIK ++ NL +++ + +LE++ + RK +++ N HL P + RL Q + + LE I
Sbjct: 20 VNKMTLKVSDTEYDVTVNSPWIVKLALPSSIMAGFPVYPIIDIKFGNKYKSKLTWY-RQRSSSNDWIEVGTGLVYIPSNDEIDHKLKLCCVPGNGTTFGPESTVE--TSGKVEAGPGLCPFQERQLFTKEILPLERFRVVSYNILADLYAETDVAKTELFPYCAPYALSLDYRKQLYLQEIVGYNADIVCLQEVDCKVFDNELQDVLLLKDMQGVLTRKGASVAEGVATFFSTRKFRLVETMKSELGEEVDVNLIYRNIWNKIK---KNKNLSERFKERTTVLQVVILESLWDSTRK-IIVGNTHLFFHPDADHIRLLQAGMILAYLENI 342 HSP 2 Score: 45.8246 bits (107), Expect = 3.383e-41 Identity = 29/114 (25.44%), Postives = 52/114 (45.61%), Query Frame = 3
Query: 1350 VIGGDFNASFDAELMRFILDKSVECSLVNNAIKLNHSLGDFYSVFKDKI-------EFTNFTPDYVGVLDHIVIDCSGLEVKHLYDVPNRLDIAKNISLPNEFHPSDHLPLLCD 1670
++ GDFN++ D+ + R + V +++ K + D I +FTNFT + LD+I L V + P+ + N+++P+ PSDH+ L+ D
Sbjct: 358 IMCGDFNSTPDSGIYRLMTTNHVPADIIDWKSKEGEEVEDLELKHPFSIDSACGTPQFTNFTAGFSACLDYIYYQKDKLNVLQVVPFPDEETLKANVAIPSITFPSDHIALIAD 471
BLAST of Endo/exonuclease/phosphatase domain-containing protein vs. TrEMBL
Match: A0A2D4N4Q5 (Endo/exonuclease/phosphatase domain-containing protein (Fragment) OS=Micrurus spixii OX=129469 PE=4 SV=1) HSP 1 Score: 137.502 bits (345), Expect = 1.120e-39 Identity = 95/340 (27.94%), Postives = 169/340 (49.71%), Query Frame = 2
Query: 365 LIKINEVIYQIYFKPPWIKTCKLPKITMVNIPITPILDLENVNESELSINWY---------VSKSSSSDDWIKCHTGT--IFIPSENYLNFFIKLQV--NSTLRNKNQNFQLISTSPIQQYPQM-EYQKLNLFNP-ILSDKTFRICSYNILSHIYAETDKAKSVLYRHCNPEFLTRDYRQCLIFGELLQHKSDIIFLQEVDQSFYQKSLYPILQSYNYEGIFQKKSRTNWEGQAIFWNINKFKLIDNISIPSLSMVINEENSEVYKKIKRFLRD-----TNLYNKWQSTGQCMTGCVLETVSLADRKRLMLCNNHLICDPKLEIFRLFQLAVGMLQLEQI 1324
++ E Y++ PP + +LP+ M P+ P L +E + + WY S +++S+ W++ G+ +F+P+ + +KL + R ++ S P++ P ++ +L+ I + R+ SYNIL+ IYA T+ +++VLY +C P L DYRQ L+ EL + +DII LQEVD+S + SL P L ++ EG+F+ K R + EG A F+ +KF+L+ I + + + E+ ++R LRD + + VL++ + + RK + + N HL PK E RL Q+A+ + ++ +
Sbjct: 1 VLHSGEARYRVERNPPRLTEVQLPRSLMAGFPVCPKLQVEFGSARDCLFRWYYEQKIEPAETSSAAASNSWVEAPAGSERVFMPTNAQIGRRLKLVCIPGNGERRYGLPREVESVGPVEAGPGACTFEARHLYTKKIAAPGLIRLVSYNILADIYARTELSRTVLYPYCAPYSLELDYRQNLLKKELAGYNADIICLQEVDKSVFVDSLGPALDAFGLEGLFRIKERQH-EGLATFYRRDKFRLLSQHDI-AFNQALLED------PLQRELRDKVATCPQVEESLLKRSSALQVSVLQSQNDSSRK-ICVANTHLFWHPKGENIRLIQVAIALSHIKHV 331 HSP 2 Score: 57.3806 bits (137), Expect = 1.120e-39 Identity = 35/118 (29.66%), Postives = 60/118 (50.85%), Query Frame = 3
Query: 1347 VVIGGDFNASFDAELMRFILDKSV---------ECSLVNNAIKLNHSLGDFYSVFKDKIEFTNFTPDYVGVLDHIVIDCSGLEVKHLYDVPNRLDIAKNISLPNEFHPSDHLPLLCDI 1673
+++ GDFNA+ F+ S+ E A+ L H G + + +TN+ + G LD+I ID + LEV+ + +P+ ++ + +LP+ HPSDH+ L+CDI
Sbjct: 341 LILCGDFNATPSTGTYTFVNSGSITEDHESWDSEVKEQRFAMSLTHQFGLKSAC--GEPAYTNYVGGFHGCLDYIFIDANVLEVEQVIPLPSHEEVTTHQALPSVSHPSDHIALICDI 456
BLAST of Endo/exonuclease/phosphatase domain-containing protein vs. TrEMBL
Match: V8PEM5 (2',5'-phosphodiesterase 12 (Fragment) OS=Ophiophagus hannah OX=8665 GN=Pde12 PE=4 SV=1) HSP 1 Score: 136.732 bits (343), Expect = 1.702e-39 Identity = 93/328 (28.35%), Postives = 163/328 (49.70%), Query Frame = 2
Query: 365 LIKINEVIYQIYFKPPWIKTCKLPKITMVNIPITPILDLENVNESELSINWYVSK--SSSSDDWIKCHTGT--IFIPSENYLNFFIKLQV--NSTLRNKNQNFQLISTSPIQQYPQM-EYQKLNLFNP-ILSDKTFRICSYNILSHIYAETDKAKSVLYRHCNPEFLTRDYRQCLIFGELLQHKSDIIFLQEVDQSFYQKSLYPILQSYNYEGIFQKKSRTNWEGQAIFWNINKFKLIDNISIPSLSMVINEENSEVYKKIKRFLRDTNLYNKWQSTGQCMTGCVLETVSLADRKRLMLCNNHLICDPKLEIFRLFQLAVGMLQLEQI 1324
+++I E Y++ PP + +LP+ M P+ P L +E + + WY + + W++ G+ +F+P+ + +KL + R + S P++ P ++ +L+ I + R+ SYNIL+ IYA T+ +++VLY +C P L DYRQ L+ EL + +DII LQEVD+S + SL P L ++ EG+F+ K R + EG A F+ +KF+L+ I + + + E+ ++R LRD L++ + + RK + + N HL PK E RL Q+A+ + ++ +
Sbjct: 143 VLQIGETRYRVERNPPTLTEVQLPRSLMAGFPVCPKLQVEFGSARDCLFRWYYEQKIEPAETSWVEAPAGSERVFMPTNAQIGRRLKLVCIPGNGERRYGLPREAESVGPVEAGPGACTFEARHLYTKKIAAPGLIRVVSYNILADIYARTELSRTVLYPYCAPYSLELDYRQNLLKKELAGYNADIICLQEVDKSVFVDSLGPALDAFGLEGLFRIKERQH-EGLATFYRRDKFRLLSQHDI-AFNQALLED------PLQRELRDKVATCPQVEESLLKRSSALQSQNDSSRK-ICVANTHLFWHPKGENIRLIQVAIALSHIKHV 461 HSP 2 Score: 56.9954 bits (136), Expect = 1.702e-39 Identity = 36/118 (30.51%), Postives = 60/118 (50.85%), Query Frame = 3
Query: 1347 VVIGGDFNASFDAELMRFILDKSV---------ECSLVNNAIKLNHSLGDFYSVFKDKIEFTNFTPDYVGVLDHIVIDCSGLEVKHLYDVPNRLDIAKNISLPNEFHPSDHLPLLCDI 1673
+++ GDFNA+ F+ S+ E A+ L H G S + +TN+ + G LD+I ID + LEV+ + +P+ ++ + +LP+ HPSDH+ L+CDI
Sbjct: 471 LILCGDFNATPSTGTYTFVNSGSITEDHESWDSEVKEQRFAMSLTHQFG-LKSACGEPA-YTNYVGGFHGCLDYIFIDANVLEVEQVIPLPSHEEVTTHQALPSVSHPSDHIALICDI 586
BLAST of Endo/exonuclease/phosphatase domain-containing protein vs. Ensembl Cavefish
Match: pde12 (phosphodiesterase 12 [Source:NCBI gene;Acc:103036143]) HSP 1 Score: 134.035 bits (336), Expect = 6.378e-33 Identity = 97/375 (25.87%), Postives = 184/375 (49.07%), Query Frame = 2
Query: 311 NKICISDLTIN-DLLISNILIKINEVIYQIYFKPPWIKTCKLPKITMVNIPITPILDLENVNESELSINWYVSKSSSSDD------------------------WIKCHTGTIFIPSENYLNFFIKLQVNSTLRNKNQNF----QLISTSPIQQYPQM-EYQKLNLFNPILSDKT-FRICSYNILSHIYAETDKAKSVLYRHCNPEFLTRDYRQCLIFGELLQHKSDIIFLQEVDQSFYQKSLYPILQSYNYEGIFQKKSRTNWEGQAIFWNINKFKLIDNISIP-SLSMVINEENSEVYKKIKRFLRDTNLYNKWQSTGQCMTGCVLETVSLADRKRLM-LCNNHLICDPKLEIFRLFQLAVGMLQLEQIKYQY 1336
N +S+ +IN + ++ + E Y+I PP T +LP + P+ P L++E + + WY +S ++ W++ + ++ PS L+ +KL++ T + N + +L++ ++ P + + +++ ++D T R+ SYNIL+ IYA+T+ +K+VLY +C P L DYRQ LI EL + +DI+ LQEVD+ + SL P L ++ +G+F+ K + + EG A F+ +KF+L+ + S ++ + +S + +K+ + L K + VL++V D +++ + N HL PK RL Q+AV + L+++ ++
Sbjct: 108 NGDSVSEDSINSEAWQDGAVLHVGENKYRIERNPPSFTTAELPASVLSGFPVCPRLEIEFGHLKDCKFTWYKERSPNAHAQQQEQHPTESTESSELGGSELNTCWLEAGSERVYTPSN--LDIGLKLKLKCTPGDGNARYGLTKELVTPEAVEAGPGVCTFDNRHMYTRKVTDATTVRVVSYNILADIYAQTELSKTVLYPYCAPYALGLDYRQSLIKKELSGYNADIVCLQEVDKGVFSDSLCPALDAFGMDGVFRVKEKQH-EGLATFYRRSKFRLLGQHDVMLSEALTTDAVHSALLEKVS---TNPTLMEKVVQRSTTLQVTVLQSV--GDPSKIVYVGNTHLYWHPKGSNVRLIQVAVALQHLKRVTEEH 474
BLAST of Endo/exonuclease/phosphatase domain-containing protein vs. Ensembl Cavefish
Match: angel2 (angel homolog 2 [Source:NCBI gene;Acc:103025889]) HSP 1 Score: 70.4774 bits (171), Expect = 2.427e-12 Identity = 38/103 (36.89%), Postives = 60/103 (58.25%), Query Frame = 2
Query: 746 FRICSYNILSHIYAETDKAKSVLYRHCNPEFLTRDYRQCLIFGELLQHKSDIIFLQEVDQSFYQKSLYPILQSYNYEGIFQKKSRTNWEGQAIFWNINKFKLI 1054
F + SYNILS E + + LY+HCNP L YR I EL +H +DI+ LQEV + YQK + P+L+S Y +++++ +G A+ + ++F L+
Sbjct: 192 FSVMSYNILSQ---ELLLSNAYLYKHCNPRILEWRYRFTNIIKELERHNADIMCLQEVQEDHYQKQIKPMLESLGYHCEYKRRTGRKPDGCAVVFRRDRFSLL 291
BLAST of Endo/exonuclease/phosphatase domain-containing protein vs. Ensembl Cavefish
Match: cnot6a (CCR4-NOT transcription complex subunit 6 [Source:NCBI gene;Acc:103025554]) HSP 1 Score: 62.003 bits (149), Expect = 9.182e-10 Identity = 60/215 (27.91%), Postives = 95/215 (44.19%), Query Frame = 2
Query: 746 FRICSYNILSHIYAETDKAKSVLYRHCNPEFLTRDYRQCLIFGELLQHKSDIIFLQEVDQSFYQKSLYPILQSYNYEGIFQKKSRT---------NWEGQAIFWNINKFKLIDNISIP--SLSMVINEENSEVYKKIKRFLRDTNLYNK----------WQSTGQCMTGCVLETVSLADRKRLMLCNNHLICDPKLEIFRLFQLAVGMLQLEQIK 1327
F + YN+L YA LY +C L +YR+ I E+L +DII LQEV+ Y L+ + YEG F KSR + +G AIF+ +KF L+ ++ L+M N E SEV + R + N+ QS G+ + G +++ +++ N H+ DP+ +L Q M+ L ++K
Sbjct: 188 FSVMCYNVLCDKYATRQ-----LYGYCPSWALNWEYRKKSIMQEILNCSADIISLQEVETEQYYNFFLVELKEHGYEGFFSPKSRARTMSESDRKHVDGCAIFYKTDKFSLVQKHTVEFNQLAMA-NSEGSEVM--LNRVMTKDNIGVAVLLELRKEIMEQSAGKPLHGM--------EKQLVLVANAHMHWDPEYSDVKLVQT---MMFLSEVK 383
BLAST of Endo/exonuclease/phosphatase domain-containing protein vs. Ensembl Cavefish
Match: cnot6b (CCR4-NOT transcription complex subunit 6 [Source:NCBI gene;Acc:103047334]) HSP 1 Score: 61.6178 bits (148), Expect = 1.396e-9 Identity = 59/210 (28.10%), Postives = 94/210 (44.76%), Query Frame = 2
Query: 746 FRICSYNILSHIYAETDKAKSVLYRHCNPEFLTRDYRQCLIFGELLQHKSDIIFLQEVDQSFYQKSLYPILQSYNYEGIFQKKSRT---------NWEGQAIFWNINKFKLIDNISIP--SLSMVINEENSEVYKKIKRFLRDTN-----LYNKWQSTGQCMTGCVLETVSLADRKRLMLCNNHLICDPKLEIFRLFQLAVGMLQLEQIK 1327
F + YN+L YA LY +C P L +YR+ I E+L +DII LQEV+ Y K L+ Y+G F KSR + +G AIF+ KF ++ ++ L+M N E SE + R + N L + + +G L + +++ L++ N H+ DP+ +L Q M+ L ++K
Sbjct: 189 FSVMCYNVLCDKYATRQ-----LYGYCPPWALNWEYRKKSIMQEILSCNADIISLQEVETEQYYKFFLVELKGQGYDGFFSPKSRARTMSESDRKHVDGCAIFYKTEKFTVVQKHTVEFNQLAMA-NSEGSEAM--LNRVMTKDNIGVAVLLELRREMMEITSGKSLHGM---EKQLLLVANAHMHWDPEYSDVKLVQT---MMFLSEVK 384
BLAST of Endo/exonuclease/phosphatase domain-containing protein vs. Ensembl Cavefish
Match: cnot6l (CCR4-NOT transcription complex, subunit 6-like [Source:NCBI gene;Acc:553665]) HSP 1 Score: 60.4622 bits (145), Expect = 3.206e-9 Identity = 57/227 (25.11%), Postives = 98/227 (43.17%), Query Frame = 2
Query: 680 QQYPQMEYQKLNLFNPILSDKTFRICSYNILSHIYAETDKAKSVLYRHCNPEFLTRDYRQCLIFGELLQHKSDIIFLQEVDQSFYQKSLYPILQSYNYEGIFQKKSRT---------NWEGQAIFWNINKFKLIDNISIP-SLSMVINEENSEVYKKIKRFLRDTNLYNK--WQSTGQCMTGCVLETVSLADRKRLMLCNNHLICDPKLEIFRLFQLAVGMLQLEQI 1324
+Q PQ + L + + F + YN+L YA LY +C L +YR+ I E+ +DII LQEV+ Y L+ Y+G F KSR + +G A+F+ KF L+ ++ + + N E SEV + R + N+ + + G + S +++ L++ N H+ DP+ +L Q + + +L+ I
Sbjct: 162 EQLPQRPWITLKERDQTMPTAVFTVMCYNVLCDKYATRQ-----LYGYCPSWALNWEYRKKGIMEEITHCDADIISLQEVETEQYYTFFLETLKERGYDGFFCPKSRAKLVSEQERKHVDGCAVFFKTEKFALVQKHTVEFNQVAMANSEGSEVM--LNRVMTKDNIGVAVLLEVKKEMFAGGI---KSPTEKQLLLVANAHMHWDPEYSDVKLIQTMMFLSELKSI 378
BLAST of Endo/exonuclease/phosphatase domain-containing protein vs. Ensembl Sea Lamprey
Match: cnot6l (CCR4-NOT transcription complex, subunit 6-like [Source:NCBI gene;Acc:553665]) HSP 1 Score: 58.5362 bits (140), Expect = 2.689e-9 Identity = 62/238 (26.05%), Postives = 97/238 (40.76%), Query Frame = 2
Query: 665 STSPIQQYPQMEYQKLNLFNPILSDKTFRICSYNILSHIYAETDKAKSVLYRHCNPEFLTRDYRQCLIFGELLQHKSDIIFLQEVDQSFYQKSLYPILQSYNYEGIFQKKSRTNW---------EGQAIFWNINKFKLIDN--ISIPSLSMVINEENSEVYKKIKRFLRDTNL-------YNKWQSTGQCMTGCVLETVSLADRKRLMLCNNHLICDPKLEIFRLFQLAVGMLQLEQI 1324
S P Q P+ Q N + ++ YN+L YA LY +C L +YR+ I E++Q+ +DII LQEV+ Y P L+ Y GIF KSR +G A+F+ +KF L+ + L+M N E SE + R + N+ G C + ++ L++ N H+ DP+ +L Q + + +L I
Sbjct: 165 SVQPDQPPPRPWIQLANPDRVRPPARLTKVMCYNVLCDKYATRQ-----LYGYCPTWALAWEYRKKGIMQEIMQYSADIISLQEVETDQYWNFFLPELKLQGYSGIFSSKSRARTMSEQERKFVDGCAVFFKSDKFTLMKEHLVEFNQLAMA-NSEGSEAM--LNRVMTKDNIGVAVLLEVKDVNFQGSCELHVCNDI-----KQTLLVANAHIHWDPEFSDVKLIQTMMFLSELRSI 389
BLAST of Endo/exonuclease/phosphatase domain-containing protein vs. Ensembl Sea Lamprey
Match: nocta (nocturnin a [Source:ZFIN;Acc:ZDB-GENE-050208-306]) HSP 1 Score: 55.0694 bits (131), Expect = 1.937e-8 Identity = 37/133 (27.82%), Postives = 59/133 (44.36%), Query Frame = 2
Query: 698 EYQKLNLFNPILSDKTFRICSYNILSHIYAETDKAKSVLYRHCNPEFLTRDYRQCLIFGELLQHKSDIIFLQEVDQSFYQKSLYPILQSYNYEGIFQKKSRT---------NWEGQAIFWNINKFKLIDNISI 1069
E+ + +P +FRI +N+L+ E + C P LT R LI E++ ++ D+I LQEVD+ Y + P L Y G F K + +G AIF+ +F+L+ +I
Sbjct: 64 EFVPVEGLDPSPPTHSFRIMQWNVLAQALGEGKDN----FVCCRPADLTWAARWPLILDEIVSYQPDLICLQEVDR--YHDAFSPALNQLGYGGAFVPKRHSPCLDVQPNYGPDGCAIFYRKERFELLGGYAI 190
BLAST of Endo/exonuclease/phosphatase domain-containing protein vs. Ensembl Sea Lamprey
Match: angel2 (angel homolog 2 (Drosophila) [Source:NCBI gene;Acc:562704]) HSP 1 Score: 48.1358 bits (113), Expect = 3.423e-6 Identity = 32/103 (31.07%), Postives = 51/103 (49.51%), Query Frame = 2
Query: 743 TFRICSYNILSHIYAETDKAKSVLYRHCNPEFLTRDYRQCLIFGELLQHKSDIIFLQEVDQSFYQKSLYPILQSYNYEGIFQKKSRTNWEGQAIFWNINKFKL 1051
F + +YNILS E + + LYRHCN L YR + E+ + +D++ LQEV + Y L P L Y ++ ++ +G AI + ++F L
Sbjct: 4 AFSVMTYNILSQTLLEDN---AYLYRHCNRSVLEWAYRFPNLIQEIERFNADVLCLQEVQKDHYIDQLKPHLIKLGYSCHYKMRTGDKNDGCAICFKRSRFSL 103
BLAST of Endo/exonuclease/phosphatase domain-containing protein vs. Ensembl Sea Lamprey
Match: angel2 (angel homolog 2 (Drosophila) [Source:NCBI gene;Acc:562704]) HSP 1 Score: 48.1358 bits (113), Expect = 3.889e-6 Identity = 32/103 (31.07%), Postives = 51/103 (49.51%), Query Frame = 2
Query: 743 TFRICSYNILSHIYAETDKAKSVLYRHCNPEFLTRDYRQCLIFGELLQHKSDIIFLQEVDQSFYQKSLYPILQSYNYEGIFQKKSRTNWEGQAIFWNINKFKL 1051
F + +YNILS E + + LYRHCN L YR + E+ + +D++ LQEV + Y L P L Y ++ ++ +G AI + ++F L
Sbjct: 21 AFSVMTYNILSQTLLEDN---AYLYRHCNRSVLEWAYRFPNLIQEIERFNADVLCLQEVQKDHYIDQLKPHLIKLGYSCHYKMRTGDKNDGCAICFKRSRFSL 120
BLAST of Endo/exonuclease/phosphatase domain-containing protein vs. Ensembl Sea Lamprey
Match: angel2 (angel homolog 2 (Drosophila) [Source:NCBI gene;Acc:562704]) HSP 1 Score: 48.1358 bits (113), Expect = 3.966e-6 Identity = 32/103 (31.07%), Postives = 51/103 (49.51%), Query Frame = 2
Query: 743 TFRICSYNILSHIYAETDKAKSVLYRHCNPEFLTRDYRQCLIFGELLQHKSDIIFLQEVDQSFYQKSLYPILQSYNYEGIFQKKSRTNWEGQAIFWNINKFKL 1051
F + +YNILS E + + LYRHCN L YR + E+ + +D++ LQEV + Y L P L Y ++ ++ +G AI + ++F L
Sbjct: 20 AFSVMTYNILSQTLLEDN---AYLYRHCNRSVLEWAYRFPNLIQEIERFNADVLCLQEVQKDHYIDQLKPHLIKLGYSCHYKMRTGDKNDGCAICFKRSRFSL 119
BLAST of Endo/exonuclease/phosphatase domain-containing protein vs. Ensembl Yeast
Match: CCR4 (Component of the CCR4-NOT transcriptional complex; CCR4-NOT is involved in regulation of gene expression; component of the major cytoplasmic deadenylase, which is involved in mRNA poly(A) tail shortening [Source:SGD;Acc:S000000019]) HSP 1 Score: 73.1738 bits (178), Expect = 2.265e-22 Identity = 62/225 (27.56%), Postives = 101/225 (44.89%), Query Frame = 2
Query: 689 PQMEY----QKLNLFNPILSDKTFRICSYNILSHIYAETDKAKSVLYRHCNPEFLTRDYRQCLIFGELLQHKSDIIFLQEVDQSFYQKSLYPILQSYNYEGIFQKKSRTNW---------EGQAIFWNINKFKLIDNISIPSLSMVINEENSEVYKKIKRFLRDTNLYNKWQSTGQCMTGCVLETVSLADRKRLMLCNNHLICDPKLEIFRLFQLAVGMLQLEQI 1324
PQ EY Q L+ +TF + SYN L YA T K +YR+ L+ DYR+ + ++L + SD++ LQEV+ +++ P+L + Y GIF K+R +G IF+ ++FKLI ++ + S + K K+F R + N+ + L+ + D + HL DPK + FQ+ V + LE +
Sbjct: 482 PQREYDSLQQSTEHLATDLAKRTFTVLSYNTLCQHYA-TPK----MYRYTPSWALSWDYRRNKLKEQILSYDSDLLCLQEVESKTFEEYWVPLLDKHGYTGIFHAKARAKTMHSKDSKKVDGCCIFFKRDQFKLITKDAM---------DFSGAWMKHKKFQRTEDYLNRAMNKDNVALFLKLQHIPSGD--TIWAVTTHLHWDPKFNDVKTFQVGVLLDHLETL 690 HSP 2 Score: 49.6766 bits (117), Expect = 2.265e-22 Identity = 35/117 (29.91%), Postives = 54/117 (46.15%), Query Frame = 3
Query: 1347 VVIGGDFNASFDAELMRFILDKSVECSLVNNAIKL----------NHSLGDFYSVFKDKIEFTNFTPDYVGVLDHIVIDCSGLEVKHLYDVPNRLDIAKNISLPNEFHPSDHLPLLC 1667
V+I GDFN+ ++ + I V+ N N +L Y+ + + FTNFTP + V+D+I L V+ L + ++K I PN+ PSDH+PLL
Sbjct: 708 VLICGDFNSYINSAVYELINTGRVQIHQEGNGRDFGYMSEKNFSHNLALKSSYNCIGE-LPFTNFTPSFTDVIDYIWFSTHALRVRGLLGEVDPEYVSKFIGFPNDKFPSDHIPLLA 823
BLAST of Endo/exonuclease/phosphatase domain-containing protein vs. Ensembl Nematostella
Match: EDO45845 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RRK8]) HSP 1 Score: 101.293 bits (251), Expect = 1.273e-22 Identity = 76/307 (24.76%), Postives = 140/307 (45.60%), Query Frame = 2
Query: 194 FNKMISKLYFSSNKRKNKKIKTEIPIDY-CEIFALDIKNQNKICISDLTINDLLISNILIKINEVIYQIYFKPPWIKTCKLPKITMVNIPITPILDLENVNESELSINWYVSK----------SSSSDDWIKCHTGTIFIPSENYLNFFIKLQVNSTLRNKNQNFQLISTSPIQ---QYPQMEYQKLNLFN-PILSDKTFRICSYNILSHIYAETDKAKSVLYRHCNPEFLTRDYRQCLIFGELLQHKSDIIFLQEVDQSFYQKSLYPILQSYNYEGIFQKKSRTNWEGQAIFWNINKFKLIDNISI 1069
K ++++ S+N++ KK K + I + + + + DL + ++ I E + + PP + + LP MV+ P+ P++ LE W+ S+ S + W + T + P + ++KL + ++ + + SPI+ + + ++ +L+ L R SYNIL+ YA + A +VLY +C P L YR+ ++ EL+ + +DII LQE Q + L P ++ Y+GI + K+ EG+AIF+N +KF+LI +
Sbjct: 36 LKKSLARISLSANQKSRKKDKKAGKGNKDISIPSASLTFEGSLLDEDLPNVEAWKDGSVLIIGEEQFSVLVNPPTVLSLFLPSHIMVDFPVYPVIKLEFAELKYCMFEWFRSENPEPSAASLPSVTECAWEEVGTEFCYKPCLQDIGCYLKLVCTPSRQDPTNGLKAETVSPIRVAAEPGRCPFENRHLYTLKKLEPGHIRCVSYNILADAYAREEFALNVLYPYCPPYALDIGYRKQVLMKELIGYNADIICLQECGQKLFDGFLLPCMELEGYQGIIKCKAGEIPEGEAIFFNRDKFELIKTCDV 342
BLAST of Endo/exonuclease/phosphatase domain-containing protein vs. Ensembl Nematostella
Match: EDO30336 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T131]) HSP 1 Score: 62.003 bits (149), Expect = 3.728e-10 Identity = 53/217 (24.42%), Postives = 92/217 (42.40%), Query Frame = 2
Query: 734 SDKTFRICSYNILSHIYAETDKAKSVLYRHCNPEFLTRDYRQCLIFGELLQHKSDIIFLQEVDQSFYQKSLYPILQSYNYEGIFQKKSRT---------NWEGQAIFWNINKFKLIDNI--SIPSLSMVINEENSEVYKKIKRFLRDTNLYNKWQSTGQCMTGCVLET-----VSLADRKRLMLCNNHLICDPKLEIFRLFQLAVGMLQLEQIKYQY 1336
S F + +N+L Y + + Y +C L DYR+ I E+L + +DI+ LQEV+ + P L+ Y GIF KSR + +G AIF+ KF ++ L+M N + S+ ++ N+ + +LE + +++++ N H+ DP+ +L Q + M +L+ I QY
Sbjct: 180 SSGNFSVMCFNVLCDKYCTSQQ-----YGYCPTWALNWDYRKTAIMKEILHYGADIVSLQEVETEQFHNFFLPQLKQDGYNGIFSPKSRARTMSEDDRKHVDGCAIFYRTTKFTMVKEFLTEFNQLAMA-NAQGSD------------DMLNRVMTKDNIGIAVLLELKDTGYIGYNGGQQVLVSNAHIHWDPEFRDVKLIQTVLLMHELQMILKQY 378
BLAST of Endo/exonuclease/phosphatase domain-containing protein vs. Ensembl Nematostella
Match: EDO40210 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S800]) HSP 1 Score: 50.447 bits (119), Expect = 3.856e-7 Identity = 28/96 (29.17%), Postives = 49/96 (51.04%), Query Frame = 2
Query: 758 SYNILSHIYAETDKAKSVLYRHCNPEFLTRDYRQCLIFGELLQHKSDIIFLQEVDQSFYQKSLYPILQSYNYEGIFQKKSRTNWEGQAIFWNINKF 1045
SYN+L+ + A LY C L +YR+ + E+L +DI+ LQEV+ + +P L Y+G ++K++ +G A F+ ++F
Sbjct: 2 SYNVLADGLMQ---AHPGLYEECEERCLDWEYRKKNLLKEILHCNADILCLQEVESEHFDNWFFPELCKAGYKGFYKKRTGKKSDGCATFYKKSRF 94
BLAST of Endo/exonuclease/phosphatase domain-containing protein vs. Ensembl Nematostella
Match: EDO42961 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S059]) HSP 1 Score: 50.8322 bits (120), Expect = 8.742e-7 Identity = 44/153 (28.76%), Postives = 68/153 (44.44%), Query Frame = 2
Query: 812 LYRHCNPEFLTRD----YRQCLIFGELLQHKSDIIFLQEVDQSFYQKSLYPILQSYNYEGIFQKKSRTNWEGQAIFWNINKFKLIDNISIPSLSMVINEENSEVYKKIKRFLRDTNLYNKWQSTGQCMTGCVLETVSLADRKRLMLCNNHLIC 1258
+Y H +FL RD R L+ E+ +DI LQE+D +Y + + S Y G++ KK+ +G AIF+ +KFK + LS I++ + KK+ + TG + LE SL D L + N H +C
Sbjct: 1 MYPHTELKFLFRDGISSRRHHLLTEEIRWLNADIFCLQELDDWYYNGIIDKFMDSLGYSGVYMKKADPKLDGLAIFYRRSKFKKA-KTDMVLLSDCIDKLTGD--KKMTGY-----------KTGHVLLMVALE--SLEDGSILAIGNTHSLC 137
BLAST of Endo/exonuclease/phosphatase domain-containing protein vs. Ensembl Medaka
Match: pde12 (phosphodiesterase 12 [Source:NCBI gene;Acc:101162595]) HSP 1 Score: 139.813 bits (351), Expect = 2.260e-40 Identity = 95/335 (28.36%), Postives = 168/335 (50.15%), Query Frame = 2
Query: 359 NILIKINEVIYQIYFKPPWIKTCKLPKITMVNIPITPILDLENVNESELSINWYV--SKSSSSDD-------WIKCHTGTIFIPSENYLNFFIKLQVNSTLRNKNQNF-QLISTSPIQQYPQM-EYQKLNLFNPILSD-KTFRICSYNILSHIYAETDKAKSVLYRHCNPEFLTRDYRQCLIFGELLQHKSDIIFLQEVDQSFYQKSLYPILQSYNYEGIFQKKSRTNWEGQAIFWNINKFKLIDNISIP-SLSMVINEENSEVYKKIKRFLRDTNLYNKWQSTGQCMTGCVLETVSLADRKRLMLCNNHLICDPKLEIFRLFQLAVGMLQLEQI 1324
++++ +V + ++ PP + T +LP + P+ P L++E N + W+ S+SS D W + + + +PS + +KL+ ++ +L+S S ++ P + + + + + R+ SYNIL+ IYA+T+ +K+VLY +C P L DYRQ L+ EL + DI+ LQEVD+ + SL P L ++ +G+F+ K + + EG A F+ +KF+L+ + I S ++ + +SE+ ++I + L K + VLE ADRK L++ N HL PK RL Q+ V + L +
Sbjct: 130 GAVLQVGDVTFTVHRNPPTLTTAELPLSLLSGFPVCPKLEVEFANLQDSEFTWFRENPPSTSSADGLDLDSSWTRVGSARVHVPSNQDIGCRLKLRCTPKEGGRSGPAKELVSVSAVEAGPGVCTFDGRHAYTAKEAAWPAVRVVSYNILADIYAQTELSKTVLYPYCAPYALQLDYRQNLVKKELAGYNGDILCLQEVDKGVFADSLSPALDAFGLDGVFRIKEKQH-EGLATFYRRSKFQLLSSHDIMFSEALTSDPLHSELLQRIS---GNVALKEKVLQRSTSLQVTVLEDRFRADRK-LIVANTHLYWHPKGGNVRLVQVGVALRHLSHV 459 HSP 2 Score: 46.595 bits (109), Expect = 2.260e-40 Identity = 30/119 (25.21%), Postives = 56/119 (47.06%), Query Frame = 3
Query: 1359 GDFNASFDAELMRFILDKSV--------------ECSLVNNAIKLNHSLGDFYSVFKDKIEFTNFTPDYVGVLDHIVIDCSGLEVKHLYDVPNRLDIAKNISLPNEFHPSDHLPLLCDI 1673
GDFN+ D+ L + + + SV CS+ +L S + +TN+ + G LD++ I ++V+ + +P+ ++ +LP+ HPSDH+ L+CD+
Sbjct: 473 GDFNSMPDSGLFQLLSEGSVPEQHPDWSGLGPEESCSM-----ELTSPFPPLLSAC-GQPAYTNYVGGFHGCLDYVFIQPQSMKVEQVIPLPSHQEVTAYEALPSLAHPSDHIALVCDL 585
BLAST of Endo/exonuclease/phosphatase domain-containing protein vs. Ensembl Medaka
Match: angel1 (angel homolog 1 [Source:NCBI gene;Acc:101168336]) HSP 1 Score: 70.0922 bits (170), Expect = 3.792e-12 Identity = 72/311 (23.15%), Postives = 132/311 (42.44%), Query Frame = 2
Query: 422 TCKLPKITMVNIPITPILDLENVNESELSINWYVSKSSSSDDWIKCH-----TGTIFIPSENYLNFFIKLQVNSTLRNKNQNFQLISTSPIQQYPQMEYQKLNLFNPILSDKT--FRICSYNILSHIYAETDKAKSVLYRHCNPEFLTRDYRQCLIFGELLQHKSDIIFLQEVDQSFYQKSLYPILQSYNYEGIFQKKSRTNWEGQAIFWNINKFKLIDNISIPSLSMVINEENSEVYKKIKRFLRDTNLYNKWQSTG--QCMTGCVLETVSLADRK-RLMLCNNHLICDPKLEIFRLFQLAVGMLQLEQI 1324
T P++T+ ++P L+ V E E W+ I+C + ++P E + +V L + N + I P Q SD + F + SYNIL+ E ++ LY+HC E L +YR L+ E+ + DI+ LQEV ++ Y++ L+P L Y I++ ++ T +G A+ + +F + + K++ F +T L N+ + G + V + +L + L L N HL+ +P+ +L QLA+ + +++ +
Sbjct: 212 TASAPQLTLSSLPSGTQAHLQCVEEHEEQTCWHFPHGPGLTQEIQCKPWEFPALSYYLPMEPAEQLEVIWRVWKELSDCNAAVERI---PFQ----------------FSDGSMDFTVMSYNILAQDLLELNQ---YLYKHCPLEVLDWNYRYNLLVEEIKKWTPDILCLQEVQENHYREQLHPALVEMGYSCIYKCRTGTKTDGCAVCYRSKRFAEVS------------------FTKLEFFRSETGLLNR-HNVGIVLLLRPLVAQGAALKESGPPLCLANTHLLFNPRRGDVKLAQLAIMLAEIDAV 481
BLAST of Endo/exonuclease/phosphatase domain-containing protein vs. Ensembl Medaka
Match: cnot6b (CCR4-NOT transcription complex subunit 6 [Source:NCBI gene;Acc:101160421]) HSP 1 Score: 62.3882 bits (150), Expect = 6.548e-10 Identity = 61/231 (26.41%), Postives = 98/231 (42.42%), Query Frame = 2
Query: 674 PIQQYPQMEYQKLNLFNPILSDKTFRICSYNILSHIYAETDKAKSVLYRHCNPEFLTRDYRQCLIFGELLQHKSDIIFLQEVDQSFYQKSLYPILQSYNYEGIFQKKSRT---------NWEGQAIFWNINKFKLIDNISIP--SLSMVINEENSEVYKKIKRFLRDTNLYNK--WQSTGQCMTGCVLETVSLADRKRLMLCNNHLICDPKLEIFRLFQLAVGMLQLEQIK 1327
P +Q P + L S F + YN+L YA LY +C L +YR+ I E++ SDII LQEV+ Y P L+ Y+G F KSR + +G AIF+ KF + ++ L+M N E SE + R + N+ + + M +++ +++ L++ N H+ DP +L Q M+ L ++K
Sbjct: 165 PTEQPPARSWISLQEPERTRSSALFSVMCYNVLCDKYATRQ-----LYGYCPSWALNWEYRKKSIIQEIMGCNSDIISLQEVETEQYYNFFLPELKDQGYDGFFSPKSRARTMSESDRKHVDGCAIFYKTEKFSAVQKHTVEFNQLAMA-NSEGSEAM--LNRVMTKDNIGVAVLLEVRKEMMELSSGKSLHGMEKQLLLVANAHMHWDPDYSDVKLVQT---MMFLSEVK 384
BLAST of Endo/exonuclease/phosphatase domain-containing protein vs. Ensembl Medaka
Match: cnot6b (CCR4-NOT transcription complex subunit 6 [Source:NCBI gene;Acc:101160421]) HSP 1 Score: 62.3882 bits (150), Expect = 7.235e-10 Identity = 61/231 (26.41%), Postives = 98/231 (42.42%), Query Frame = 2
Query: 674 PIQQYPQMEYQKLNLFNPILSDKTFRICSYNILSHIYAETDKAKSVLYRHCNPEFLTRDYRQCLIFGELLQHKSDIIFLQEVDQSFYQKSLYPILQSYNYEGIFQKKSRT---------NWEGQAIFWNINKFKLIDNISIP--SLSMVINEENSEVYKKIKRFLRDTNLYNK--WQSTGQCMTGCVLETVSLADRKRLMLCNNHLICDPKLEIFRLFQLAVGMLQLEQIK 1327
P +Q P + L S F + YN+L YA LY +C L +YR+ I E++ SDII LQEV+ Y P L+ Y+G F KSR + +G AIF+ KF + ++ L+M N E SE + R + N+ + + M +++ +++ L++ N H+ DP +L Q M+ L ++K
Sbjct: 165 PTEQPPARSWISLQEPERTRSSALFSVMCYNVLCDKYATRQ-----LYGYCPSWALNWEYRKKSIIQEIMGCNSDIISLQEVETEQYYNFFLPELKDQGYDGFFSPKSRARTMSESDRKHVDGCAIFYKTEKFSAVQKHTVEFNQLAMA-NSEGSEAM--LNRVMTKDNIGVAVLLEVRKEMMELSSGKSLHGMEKQLLLVANAHMHWDPDYSDVKLVQT---MMFLSEVK 384
BLAST of Endo/exonuclease/phosphatase domain-containing protein vs. Ensembl Medaka
Match: angel2 (protein angel homolog 2-like [Source:NCBI gene;Acc:111947098]) HSP 1 Score: 60.8474 bits (146), Expect = 2.168e-9 Identity = 53/216 (24.54%), Postives = 96/216 (44.44%), Query Frame = 2
Query: 725 PILSDKT---FRICSYNILSHIYAETDKAKSVLYRHCNPEFLTRDYRQCLIFGELLQHKSDIIFLQEVDQSFYQKSLYPILQSYNYEGIFQKKSRTNWEGQAIFWNINKFKLIDNISIPSLSMVINEENSEVYKKIKRFLRDTNLYNKWQSTGQCMTGCVLETVSLADRKR----LMLCNNHLICDPKLEIFRLFQLAVGMLQLEQI-KYQYGEVC 1348
P L T F + SYNILS E + + LYRHC P L+ D+R + E+ D++ LQEV + Y + LQ+ Y ++K++ +G A+ + ++F L+ + + E ++ L N+ G V+ + AD + + + N HL+ +PK +L QLA+ + +++++ + G C
Sbjct: 194 PPLGGSTAFHFTVMSYNILSQQLLEDN---AFLYRHCPPAVLSWDHRLPNLLSEIQHLHPDVLCLQEVQEDHYDNQIKAALQALGYRCEYKKRTGQKPDGCAVAFKASRFHLLSSNPV------------EFFRAGDPLLDRDNV------------GLVV-LLQPADGRSGSPPICVANTHLLYNPKRGDIKLTQLAILLAEVQRLSRLPDGSAC 381
BLAST of Endo/exonuclease/phosphatase domain-containing protein vs. Planmine SMEST
Match: SMESG000035204.1 (SMESG000035204.1) HSP 1 Score: 872.848 bits (2254), Expect = 0.000e+0 Identity = 431/435 (99.08%), Postives = 432/435 (99.31%), Query Frame = 2
Query: 47 MENQLNHIFIRNSDQINNHVLIEFEYSFENSSSLYYSFLRPISESLEVLFNKMISKLYFSSNKRKNKKIKTEIPIDYCEIFALDIKNQNKICISDLTINDLLISNILIKINEVIYQIYFKPPWIKTCKLPKITMVNIPITPILDLENVNESELSINWYVSKSSSSDDWIKCHTGTIFIPSENYLNFFIKLQVNSTLRNKNQNFQLISTSPIQQYPQMEYQKLNLFNPILSDKTFRICSYNILSHIYAETDKAKSVLYRHCNPEFLTRDYRQCLIFGELLQHKSDIIFLQEVDQSFYQKSLYPILQSYNYEGIFQKKSRTNWEGQAIFWNINKFKLIDNISIPSLSMVINEENSEVYKKIKRFLRDTNLYNKWQSTGQCMTGCVLETVSLADRKRLMLCNNHLICDPKLEIFRLFQLAVGMLQLEQIKYQYGEVCC 1351
MENQLNHIFIRNSDQINNHVLIEFEYSFENSSSLYYSFLRPISESLEVLFNKMISKLYFSSNKRKNKKIKTEIPIDYCEIFALDIKNQNKICISDLTINDLLISNILIKINEVIYQIYFKPPWIKTCKLPKITMVNIPITPILDLENVNESELSINWYVSK SSSDDWIKCHTGTIFIPSENYLNFFIKLQVNSTL NKNQNFQLISTSPIQQYPQMEYQKLNLFNPILSDKTFRICSYNILSHIYAETDKAKSVLYRHCNPEFLTRDYRQCLIFGELLQHKSDIIFLQEVDQSFYQKSLYPILQSYNYEGIFQKKSRTNWEGQAIFWNINKFKLIDNISIPSLS VINEENSEVYKKIKRFLRDTNLYNKWQSTGQCMTGCVLETVSLADRKRLMLCNNHLICDPKLEIFRLFQLAVG+LQLEQIKYQYGEVCC
Sbjct: 1 MENQLNHIFIRNSDQINNHVLIEFEYSFENSSSLYYSFLRPISESLEVLFNKMISKLYFSSNKRKNKKIKTEIPIDYCEIFALDIKNQNKICISDLTINDLLISNILIKINEVIYQIYFKPPWIKTCKLPKITMVNIPITPILDLENVNESELSINWYVSKCSSSDDWIKCHTGTIFIPSENYLNFFIKLQVNSTLTNKNQNFQLISTSPIQQYPQMEYQKLNLFNPILSDKTFRICSYNILSHIYAETDKAKSVLYRHCNPEFLTRDYRQCLIFGELLQHKSDIIFLQEVDQSFYQKSLYPILQSYNYEGIFQKKSRTNWEGQAIFWNINKFKLIDNISIPSLSKVINEENSEVYKKIKRFLRDTNLYNKWQSTGQCMTGCVLETVSLADRKRLMLCNNHLICDPKLEIFRLFQLAVGILQLEQIKYQYGEVCC 435 HSP 2 Score: 228.409 bits (581), Expect = 2.520e-67 Identity = 110/111 (99.10%), Postives = 110/111 (99.10%), Query Frame = 3
Query: 1344 CVVIGGDFNASFDAELMRFILDKSVECSLVNNAIKLNHSLGDFYSVFKDKIEFTNFTPDYVGVLDHIVIDCSGLEVKHLYDVPNRLDIAKNISLPNEFHPSDHLPLLCDIS 1676
C VIGGDFNASFDAELMRFILDKSVECSLVNNAIKLNHSLGDFYSVFKDKIEFTNFTPDYVGVLDHIVIDCSGLEVKHLYDVPNRLDIAKNISLPNEFHPSDHLPLLCDIS
Sbjct: 434 CCVIGGDFNASFDAELMRFILDKSVECSLVNNAIKLNHSLGDFYSVFKDKIEFTNFTPDYVGVLDHIVIDCSGLEVKHLYDVPNRLDIAKNISLPNEFHPSDHLPLLCDIS 544
BLAST of Endo/exonuclease/phosphatase domain-containing protein vs. Planmine SMEST
Match: SMESG000035291.1 (SMESG000035291.1) HSP 1 Score: 414.075 bits (1063), Expect = 1.736e-147 Identity = 208/434 (47.93%), Postives = 297/434 (68.43%), Query Frame = 2
Query: 59 LNHIFIRNSDQINNHVLIEFEYSFENSSSLYYSFLRPISESLEVLFNKMISKLYFSSNKRKNKKIKTEIPIDYCEIFALDIKNQNKICISDLTINDLLISNILIKINEVIYQIYFKPPWIKTCKLPKITMVNIPITPILDLENVNESELSINWYVSKSSSSDDWIKCHTGTIFIPSENYLNFFIKLQVNSTLRNKNQNFQLISTSPIQQYPQMEYQKLNLFNPI---LSDKTFRICSYNILSHIYAETDKAKSVLYRHCNPEFLTRDYRQCLIFGELLQHKSDIIFLQEVDQSFYQKSLYPILQSYNYEGIFQKKSRTNWEGQAIFWNINKFKLIDNISIPSLSMVINEENSEVYKKIKRFLRDTNLYNKWQSTGQCMTGCVLETVSLADRKRLMLCNNHLICDPKLEIFRLFQLAVGMLQLEQIKYQ-YGEVC 1348
+ +FI SDQ +N L+EF+Y + +S +YSFLRPI ESL++LF ++ SK+ ++ NKKIK + C+I +D + N++ ++L+I LL I +KINE +Y + PPWIK C LPKI MVN P+ PI + N ++ + WY KS ++++WI+C + ++FIPS+ +LN F+KL+V++ + Q F++IS +P++ +PQ YQ LF+ ++ +F +C+YNILSHIYAET +K VLYRHC+ ++L+ DYRQ LI GE++Q SD+IFLQEVDQSF+ + L+PIL+ +NY+GI+Q KS+ EGQAIFW INKFKL++NISIP LS IN+ E + ++K L DTNL KWQS GQCMTGCVL+ V + KRL+L NNHL P EIFRLFQ+ + QLE++K + YG C
Sbjct: 5 IKEMFIHYSDQSSNDALLEFDYEYTDSVKYFYSFLRPIDESLDMLFKRISSKISKIKYRKCNKKIKNHPMANNCDIKVVDSETFNELQATELSIRSLLSFKICLKINEALYNVCLNPPWIKQCYLPKICMVNCPVYPIFEAVNAENTKFNFKWYKGKSKTTNEWIECCSDSVFIPSQEHLNHFLKLEVSTAVNISRQVFKIISNNPVENFPQAHYQLSMLFDKTNINENEDSFTMCTYNILSHIYAETPHSKKVLYRHCDKKYLSHDYRQSLILGEIIQRSSDLIFLQEVDQSFFFQMLHPILKYFNYDGIYQNKSKNKLEGQAIFWKINKFKLLENISIPCLSDEINK--IESFCEMKSMLTDTNLIEKWQSMGQCMTGCVLQAVFGSTNKRLILSNNHLFFHPDYEIFRLFQVGIVFNQLERLKREYYGSAC 436 HSP 2 Score: 129.413 bits (324), Expect = 1.736e-147 Identity = 55/108 (50.93%), Postives = 79/108 (73.15%), Query Frame = 3
Query: 1350 VIGGDFNASFDAELMRFILDKSVECSLVNNAIKLNHSLGDFYSVFKDKIEFTNFTPDYVGVLDHIVIDCSGLEVKHLYDVPNRLDIAKNISLPNEFHPSDHLPLLCDI 1673
+IGGDFNASF+ + ++FI D ++ N +IKL H + + V +D +EF+NFTPDYVG+LDH++ID + +K Y P+R +I +NI+LPN+FHPSDHLPL CD+
Sbjct: 437 IIGGDFNASFEDDSIKFIFDNQIQLQYENKSIKLEHGMRNLLGVHRDVVEFSNFTPDYVGLLDHVIIDSEKIGIKRAYKTPSREEIEENIALPNKFHPSDHLPLYCDL 544
BLAST of Endo/exonuclease/phosphatase domain-containing protein vs. Planmine SMEST
Match: SMESG000062434.1 (SMESG000062434.1) HSP 1 Score: 207.994 bits (528), Expect = 2.392e-62 Identity = 135/421 (32.07%), Postives = 236/421 (56.06%), Query Frame = 2
Query: 110 IEFEYSFENSSSLYYSFLRPISESLEVLFNKMISKL-YFSSNK--RKNK-KIKTEIPIDYCEIFALDIKNQNKIC---ISDLTINDLLISNILIKINEVIYQIYFKPPWIKTCKLPKITMVNIPITPILDLENVNESELSINWYVSKSSSSDDWIKCHTGTIFIPSENYLNFFIKLQ---VNSTLRNKNQNFQLISTSPIQQYPQMEYQKLNLFNPILSDKTFRICSYNILSHIYAETDKAKSVLYRHCNPEFLTRDYRQCLIFGELLQHKSDIIFLQEVDQSFYQKSLYPILQSYNYEGIFQKKSRTNWEGQAIFWNINKFKLIDNISIPSLS-MVINEENSEVYKKIKRFLRDTN-LYNKWQSTGQCMTGCVLETVSLADRKRLMLCNNHLICDPKLEIFRLFQLAVGMLQLEQIKYQY 1336
I+F++S + +S LRP +E L +++ K+ + +NK RKNK KI T+ I + + + N+ I I + + D+LI + +I+I+++ Y + P I + KLP+I + + + P +D+E S+++ W+ S + DWI+ +G + ENY N F+KL+ N + ++ + I P Q + + + +N L++ FR+ SYNIL+ +Y+E+D + + +RHC E+L +YR+ L+ E+ + SDII LQEV+ Y+ LYP Y ++G+FQ K + EGQAIFW +KF+L++N+ + S+S +V+ ++ E +K+I F+R +N L W QC+ GCVL+ V ++L++ N HL P I R FQ++ + Q+ +K +Y
Sbjct: 3 IDFDFSDHKLCNKKFSLLRPQTEDLSNFIHRLKYKINHIVTNKILRKNKQKILTDQQIAESLVNEVVVINEKHIFDENILQMPLKDVLIEHTIIRIDKMNYNVALNVPLIVSIKLPQILLTDSFVFPQIDMEQGELSDINFLWFASLNKH--DWIQIDSGFAILIKENYKNHFLKLKCSCFNDYIVSEKISNSTIQLGPSQNALKNRWNYTSNYNDQLNE--FRVLSYNILAKMYSESDVGRQI-FRHCPDEYLDVNYRKDLLIKEIFNYHSDIICLQEVESHMYRHFLYPFYSCYYFDGLFQAKDLESMEGQAIFWRKSKFELVENVCLESISKLVLTNDHLEGFKEIVNFIRKSNILLQNWVKLKQCVAGCVLQAVDGDRLRQLIVFNTHLYFKPSANIIRSFQMSAILFQISLLKLKY 418 HSP 2 Score: 51.2174 bits (121), Expect = 2.392e-62 Identity = 36/115 (31.30%), Postives = 60/115 (52.17%), Query Frame = 3
Query: 1347 VVIGGDFNASFDAELMRFILDKSVECSLVNN-----AIKLNHSLGDFYSVFKDKIEFTNFTPDYVGVLDHIVIDCSGLEVKHLYDVPNRLDIAKNISLPNEFHPSDHLPLLCDIS 1676
V++ GDFN D+ + +LD SV + +I L+H L S + FTN+ D+ G LD+I D + L+ + +P+ ++ ++ +LPN+ PSDHL L+ D
Sbjct: 423 VILTGDFNDFRDSNAVSLVLDGSVTMKHLLTEGHELSINLSHDLL-LKSAYNS--SFTNYVLDFSGELDYIFYDSNELQCGNTVPLPSLEEVMRDQALPNKDFPSDHLALIADFQ 534
BLAST of Endo/exonuclease/phosphatase domain-containing protein vs. Planmine SMEST
Match: SMESG000023679.1 (SMESG000023679.1) HSP 1 Score: 59.6918 bits (143), Expect = 6.979e-12 Identity = 48/193 (24.87%), Postives = 88/193 (45.60%), Query Frame = 2
Query: 743 TFRICSYNILSHIYAETDKAKSVLYRHCNPEFLTRDYRQCLIFGELLQHKSDIIFLQEVDQSFYQKSLYPILQSYNYEGIFQKKSRTNW---------EGQAIFWNINKFKLIDNISIPSLSMVINEENSEVYKKIKRFLRDTNLYNKWQSTGQCMTGCVLETVSLA-DRKRLMLCNNHLICDPKLEIFRLFQ 1291
+F + YN+L YA T +Y +C L +YR+ I E+ ++K+DII LQE++ S Y+ L+ NY+G+F KSR+ +G AIFW + F+ + +++ + I + + + R + N+ +LE ++++L + H+ DP+ +L Q
Sbjct: 190 SFTLMCYNVLCQKYATTH-----MYPYCPAFALDWEYRKRGILEEIWKYKADIICLQELETSQYENVFSVELRKRNYDGLFVPKSRSRTMHESDSKCVDGCAIFWKVECFEKVHHVTHEFMLSCIGVSKNPAPELLNRVMNRDNV----------ALSIILEVKDPKMNKRKLCVSTGHIHWDPEYSDVKLIQ 367 HSP 2 Score: 30.0314 bits (66), Expect = 6.979e-12 Identity = 32/136 (23.53%), Postives = 65/136 (47.79%), Query Frame = 3
Query: 1347 VVIGGDFNASFDAELMRFILDKSVECSLVN-------------NAIK--------LNHSLGDFYSVFKDK----IEFTNFTPDYVGVLDHIVIDCSGLE-VKHLYDVP-NRLDIAKNISLPNEFHPSDHLPLLCDI 1673
V++ GDFN+ + ++ +++ VE S V+ +A++ L H +F +KD+ +++TN+T D+ G++D+I L + +L +P + + K + P+ SDH LL ++
Sbjct: 398 VILCGDFNSLPQSGVVDYLIKGEVERSHVDFREFGDKYLFNEWSAMQDEFVENDVLKHRF-NFDRAYKDEHESGLKWTNYTYDFRGIIDYIFFSKEHLGLLGNLKQIPESWFEQQKIVGAPHVHFNSDHFSLLVEL 532
BLAST of Endo/exonuclease/phosphatase domain-containing protein vs. Planmine SMEST
Match: SMESG000023679.1 (SMESG000023679.1) HSP 1 Score: 59.3066 bits (142), Expect = 1.600e-11 Identity = 48/193 (24.87%), Postives = 88/193 (45.60%), Query Frame = 2
Query: 743 TFRICSYNILSHIYAETDKAKSVLYRHCNPEFLTRDYRQCLIFGELLQHKSDIIFLQEVDQSFYQKSLYPILQSYNYEGIFQKKSRTNW---------EGQAIFWNINKFKLIDNISIPSLSMVINEENSEVYKKIKRFLRDTNLYNKWQSTGQCMTGCVLETVSLA-DRKRLMLCNNHLICDPKLEIFRLFQ 1291
+F + YN+L YA T +Y +C L +YR+ I E+ ++K+DII LQE++ S Y+ L+ NY+G+F KSR+ +G AIFW + F+ + +++ + I + + + R + N+ +LE ++++L + H+ DP+ +L Q
Sbjct: 390 SFTLMCYNVLCQKYATTH-----MYPYCPAFALDWEYRKRGILEEIWKYKADIICLQELETSQYENVFSVELRKRNYDGLFVPKSRSRTMHESDSKCVDGCAIFWKVECFEKVHHVTHEFMLSCIGVSKNPAPELLNRVMNRDNV----------ALSIILEVKDPKMNKRKLCVSTGHIHWDPEYSDVKLIQ 567 HSP 2 Score: 29.261 bits (64), Expect = 1.600e-11 Identity = 32/136 (23.53%), Postives = 65/136 (47.79%), Query Frame = 3
Query: 1347 VVIGGDFNASFDAELMRFILDKSVECSLVN-------------NAIK--------LNHSLGDFYSVFKDK----IEFTNFTPDYVGVLDHIVIDCSGLE-VKHLYDVP-NRLDIAKNISLPNEFHPSDHLPLLCDI 1673
V++ GDFN+ + ++ +++ VE S V+ +A++ L H +F +KD+ +++TN+T D+ G++D+I L + +L +P + + K + P+ SDH LL ++
Sbjct: 598 VILCGDFNSLPQSGVVDYLIKGEVERSHVDFREFGDKYLFNEWSAMQDEFVENDVLKHRF-NFDRAYKDEHESGLKWTNYTYDFRGIIDYIFFSKEHLGLLGNLKQIPESWFEQQKIVGAPHVHFNSDHFSLLVEL 732 The following BLAST results are available for this feature:
BLAST of Endo/exonuclease/phosphatase domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Endo/exonuclease/phosphatase domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Endo/exonuclease/phosphatase domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Endo/exonuclease/phosphatase domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Endo/exonuclease/phosphatase domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Endo/exonuclease/phosphatase domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Endo/exonuclease/phosphatase domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Endo/exonuclease/phosphatase domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Endo/exonuclease/phosphatase domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Endo/exonuclease/phosphatase domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Endo/exonuclease/phosphatase domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 1
BLAST of Endo/exonuclease/phosphatase domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 4
BLAST of Endo/exonuclease/phosphatase domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Endo/exonuclease/phosphatase domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30018103 ID=SMED30018103|Name=Endo/exonuclease/phosphatase domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=1719bpback to top protein sequence of SMED30018103-orf-1 >SMED30018103-orf-1 ID=SMED30018103-orf-1|Name=SMED30018103-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=445bp MENQLNHIFIRNSDQINNHVLIEFEYSFENSSSLYYSFLRPISESLEVLFback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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