Talin-1
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30018086 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 25Note: Hover over icons to view figure legend
Homology
BLAST of Talin-1 vs. Ensembl Human
Match: TLN1 (talin 1 [Source:HGNC Symbol;Acc:HGNC:11845]) HSP 1 Score: 970.689 bits (2508), Expect = 0.000e+0 Identity = 725/2432 (29.81%), Postives = 1223/2432 (50.29%), Query Frame = 1
Query: 55 LRIHIVDADVTKIVPLDPEATIFQLCETIRKNIREAQTKSPKSYGLYLPHDDLKKGLWLDNSKTLQHYILKRGDTIEYRNRSRWLHIRTMDGTNKTLKVDDSWTVSELMLTVCTKLGIYNYDEYSLISDKMDFSPGIDKTLSMKRGISINXXXXXXXXXXXXYHTEDGLNWLNPSQSLRQQGIEESEVLLLKRKYFFSDMNVDSRDPIQLSLLYEQLKDAVINGTHPVTLPEAIELAGLQCQVQLGNYSADKFKPGFLDLRECLPKEYQKNPKTVEKKIFNQHSKSKDLSEVEAKEKYCLLCRSFKTYGITFFLVKEKVIGKNKLIPRLLGVNKESVVQVDEKTKEIINTWPLTSIRKWAASFNGFTMDFGEYSPDEYYTAQTDKGERISQLIAGYIDIILKRKKAKDHLGVDADEESIMYEENIAPSKAIIVEH----VPKQKRSSVSEEDVVIRKKAHMANSSVRMNSQASDSVCSQDCTDFYQEDINMSRQTSSLGRTQSPSSSLTTNSMHY-RMSDDDIRQKLYIISLQDNLDTIQKYKDQLMIENKGPEIGKDEASQQWIYVNIDNSRQRMADEIGAMNAAVAQVLRSAQGLATIXXXXXXXXXXXXIAKMQNSFSLITVHLPSLMEEIRTAAYYQDQLTDEDVSGEELIAAAKRLADAFTNLIKAAYPVEDQKRSLNRKEIFDAANAVGEASSDLLQQITEQENCQIELKSERPYSIIMITEEDQLYQEELLRLAKSVANETTNLIKQVKVIAVEAENPSDQKKVVMAATETGLAISQLISTTKIVAPTIEQSVCQEQLIFSIEDVSKAIQVVVESSNKATQSEELQDLTVQAANQVQEALDTLMKHLRXXXXXXXXXXXXXXAYENI----QEXXXXXXXXXXXXXXXRRLAQATTAMISEIQLKAVNEQYKTPEERDKLINAAKQLAEATTVLIDSAKNCTMDKDEMNLRYTLREATERFIVVTYTTECATYIQEQVIDHLLVAARKAATTGTHLINTSLSAAKKSRASNFK---VCNDGRELSNQISNLIVAIKEARRDPKDHLAQLELIAACRDYIDPSEQLSQSNKYMWPTVSDPSLQTALNQSINQSVIATEELKKCVHQADLMCQHLDLSAALEQLKRLEQNLKSIKNSIERENLIPLPDEKSDESAALLIKSVRRSGSAANQFKNDLESRCVVYEQTNGEDSYQNLENLDVAGQKARELSMALDRLVHAARGVAASIEFENQESENNDKNLEKLAQLQIVNNCLEAVKAARDLVIEAKSS---PPDNDQMDRAQQASVRXXXXXXXXXXXXPGQRDLDMLSKHIESKKHQFAENRLPIQQNNNINLSNCRSELTDTTFDFNQAVNELVSAPSFNLVNKGCKK-MRMSYDRIVEICNVLVHDPFDESDSALHHLSSNRDHIANGVMIMSEDCQTLLDKVKKIQCEPDNIIVRKQLQEATKMLLDSINRLLTNISTNLRPGQKECDKTIYRLESMRPILDNPVHPISHKDYFECLDFIIDKTVQPLADSLKNIPAAVKDENNQKFIDSIYHCADSVCMLLEETAQTAYLVGVGDVRSKIGNKGLADHTSFLQIQKEISENCQTICNPDTTARQDSSLMISTAGQIAENSRKLCEASK--TIMISFPNDKIKLSDKTKITLLAVSELMTGVQNLNQNFNEDNRKEVESLSGKVQDNVAELVQLLLSYKFAGDAAIISEEAKESQGPIKAAGITVLDTAIEVIQCSKALISSEANEELFIAYSSSCKDLNDALKHLISTIKESAPGQKECDEXXXXXXXXXXQAYDSKMKIMKHRS------RTISRTFESEESYQNILQSALIQMPHCINELSRAGKKEPEQLARIFSRQTQLLESMVNSCICAANQTDLIQNSNIYLEHLITILEASEQLLKAVKKSGGNPKANSVHSQ--IDEMAQGVIESCEDLLAALDKISFKQGNVNTIVETITKSSAKVQESAIIPEKSRFGNSQSKMLDICYDMNNLTTDISSNANSESTQRLLAPLTQNLTQRYDDLCRACQGAVATLSNENNGKQLQECVQTVGKVSISLVKSTTEVR--PSVASSISNLQAKTQELHKRIDDVIQLLISSNVGTQACTQAIKILKEINSDIDTSILFVKSADIQNDDREYYSVKELFKKSRNSVIDNSSELVRNIKLIVSKDVCDVNILQESADQIAITSQSLANDVKVGLEHLNSSTSQYNIELLVSFQEVIVSLISFLEVARNTSGLPYTDPLFQNLKEEGKCSINAITSLLKVLKSMDDVNLKDFQAIDNAIIXXXXXXXXXXXXXXGISREASPVESPTSTNRLSIGSDITVSPRFAPEEINRLIPSLANVCDKILEISSPEFKPIIRQENISVVSISCSKVNNELTSACKNLLRNGPVT-DSKKQTLNTVDQLVENYTELLKNFKLYLTNPTKETR 7263
L + I +V K + +P ++ C IR+ I EA P +GL+L DD KKG+WL+ K L +Y+L+ GDT+EYR + R L IR +DGT KT+ VDDS TV+++++T+C ++GI N+DEYSL+ + M+ + T ++++ ++ +D++K++KLK+K HT+D LNWL+ ++LR+QG+EE E LLL+RK+F+SD NVDSRDP+QL+LLY Q +D ++NG+HPV+ +A E AG QCQ+Q G ++ K K GFLDL++ LPKEY K + E+KIF H +SE+EAK +Y L RS KTYG++FFLVKEK+ GKNKL+PRLLG+ KE V++VDEKTKE+I W LT+I++WAAS FT+DFG+Y D YY+ QT +GE+I+QLIAGYIDIILK+KK+KDH G++ DEES M E++++P K+ +++ V K + SV+ + M S AS + +Q +G +T+ MH M Q+ ++ ++ +Q + L + P +G+D AS+ W +D S+ + ++ A+ A A V+ G + E + + + I+ +L + ++ A L DE SG L+ AAK LA A + L+++A P + R + + AA VG+AS +LLQQI E ++ D +Q+ L++LAK+VA+ L+ + K +A E+ Q +V+ AAT+ L+ SQL++ TK+VAPTI VCQEQL+ + V+KA++ V +S AT+ +L AA V +AL+ L++H++ + A + I + + S D ++V AR LAQAT+ +++ I KA E E KL++AAK LA+AT ++++AK D + LREA E + T I+++++ L AA++AA + T I + AA +AS + + ++ QI L+ ++ ++ P AQL LIAA + ++ P ++ + K PT+ D + L+Q A EL+ +A C L++ +AL ++ LE++L+ +K + L PLP E ++ L S + SA Q + E G ++Y + DVAG L L AARGVAA +D ++ + +++ + + A L+ EAK + P D + R Q + ++ AL+ C+ LPGQRD+D + + + + LP + +S L + NQA ELV A ++G + + + R + + + + + A +R + + + +S LL K + +P ++ QL A + + DSIN+L+T + T PGQKECD + LE++R +L+NPV PI+ YF CLD +++ + + L +++ I K+ N +F D+I + ++C E AQ AYLVGV D S+ G +GL + T F + + I CQ++ P T Q ++S A +A+++ LC + + + + P K + K + + L+ ++ L+ F E+NR + + + + + V L + +F+ A IS E + + PI + T+L++A +IQ ++AL + + + + + ++D++K LI+++++ APGQ EC+ A +S ++ + S + R S+E+ + +A+ ++ H I L+ A + E QL S+ Q E + + + AA++T L+ T+ E++ QLL K++GGNPK + H+Q ++E Q + E+ EDL L++ + G V +V++IT++ ++ E + + F + Q+ M+ + ++ + +N+ + L PL LT Y L + A NE G ++ VQ +G +LV ++ PS A + L + + +++ V+ L + N GTQAC A + I +D+DT+I+F + + +RE E F R ++ + LV + K++V L ++A T LA+ VK+G L + + + L+ + ++V +L + + +G DP LK K + +TSLLK +K+++D K +A++ I +E + SP + S PE+ R+ + K + + RQE++ + + ++ ACK + V D + + L+ + Y ELL + L L P+ E +
Sbjct: 4 LSLKISIGNVVKTMQFEPSTMVYDACRIIRERIPEAPAGPPSDFGLFLSDDDPKKGIWLEAGKALDYYMLRNGDTMEYRKKQRPLKIRMLDGTVKTIMVDDSKTVTDMLMTICARIGITNHDEYSLVRELME-EKKEEITGTLRKDKTLLRDEKKMEKLKQKLHTDDELNWLDHGRTLREQGVEEHETLLLRRKFFYSDQNVDSRDPVQLNLLYVQARDDILNGSHPVSFDKACEFAGFQCQIQFGPHNEQKHKAGFLDLKDFLPKEYVK--QKGERKIFQAHKNCGQMSEIEAKVRYVKLARSLKTYGVSFFLVKEKMKGKNKLVPRLLGITKECVMRVDEKTKEVIQEWNLTNIKRWAASPKSFTLDFGDYQ-DGYYSVQTTEGEQIAQLIAGYIDIILKKKKSKDHFGLEGDEESTMLEDSVSPKKSTVLQQQYNRVGKVEHGSVALPAI--------------MRSGASGP-------ENFQ-----------VGSMPPAQQQITSGQMHRGHMPPLTSAQQALTGTINSSMQAVQAAQATLDDFDTLPPLGQDAASKAWRKNKMDESKHEIHSQVDAITAGTASVVNLTAG----------DPAETDYTAVGCAVTTISSNLTEMSRGVKLLAAL---LEDEGGSGRPLLQAAKGLAGAVSELLRSAQPASAEPR----QNLLQAAGNVGQASGELLQQIGE-------------------SDTDPHFQDALMQLAKAVASAAAALVLKAKSVAQRTEDSGLQTQVIAAATQCALSTSQLVACTKVVAPTISSPVCQEQLVEAGRLVAKAVEGCVSASQAATEDGQLLRGVGAAATAVTQALNELLQHVKAHATGAGPAGRYDQATDTILTVTENIFSSMGDAGEMVRQARILAQATSDLVNAI--KADAEGESDLENSRKLLSAAKILADATAKMVEAAKGAAAHPDSEEQQQRLREAAEGLRMAT-NAAAQNAIKKKLVQRLEHAAKQAAASATQTIAAAQHAASTPKASAGPQPLLVQSCKAVAEQIPLLVQGVRGSQAQPDSPSAQLALIAASQSFLQPGGKMVAAAKASVPTIQDQASAMQLSQCAKNLGTALAELRTAAQKAQEACGPLEMDSALSVVQNLEKDLQEVKAAARDGKLKPLPGETMEKCTQDLGNSTKAVSSAIAQL---------LGEVAQGNENYAGIAARDVAG--------GLRSLAQAARGVAAL---------TSDPAVQAI----VLDTASDVLDKASSLIEEAKKAAGHPGDPESQQRLAQVAKAVTQALNRCVSCLPGQRDVDNALRAVGDASKRLLSDSLP---PSTGTFQEAQSRLNEAAAGLNQAATELVQA------SRGTPQDLARASGRFGQDFSTFLEAGVEMAGQAPSQ--EDRAQVVSNLKGISMSSSKLLLAAKALSTDPAAPNLKSQLAAAARAVTDSINQLIT-MCTQQAPGQKECDNALRELETVRELLENPVQPINDMSYFGCLDSVMENS-KVLGEAMTGISQNAKNGNLPEFGDAISTASKALCGFTEAAAQAAYLVGVSDPNSQAGQQGLVEPTQFARANQAIQMACQSLGEPGCTQAQ----VLSAATIVAKHTSALCNSCRLASARTTNPTAKRQFVQSAKEVANSTANLVKTIKALDGAFTEENRAQCRAATAPLLEAVDNLSAFASNPEFSSIPAQISPEGRAAMEPIVISAKTMLESAGGLIQTARALAVNPRDPPSWSVLAGHSRTVSDSIKKLITSMRDKAPGQLECE--------TAIAALNSCLRDLDQASLAAVSQQLAPREGISQEALHTQMLTAVQEISHLIEPLANAARAEASQLGHKVSQMAQYFEPLTLAAVGAASKTLSHPQQMALLDQTKTLAESALQLLYTAKEAGGNPK-QAAHTQEALEEAVQMMTEAVEDLTTTLNEAASAAGVVGGMVDSITQAINQLDEGPMGEPEGSFVDYQTTMVRTAKAIAVTVQEMVTKSNTSPEE--LGPLANQLTSDYGRLASEAKPAAVAAENEEIGSHIKHRVQELGHGCAALVTKAGALQCSPSDAYTKKELIECARRVSEKVSHVLAALQAGNRGTQACITAASAVSGIIADLDTTIMFATAGTL---NREGT---ETFADHREGILKTAKVLVEDTKVLVQNAAGSQEKLAQAAQSSVATITRLADVVKLGAASLGAEDPETQVVLINAVKDVAKALGDLISATKAAAGKVGDDPAVWQLKNSAKVMVTNVTSLLKTVKAVEDEATKGTRALE--------------ATTEHIRQELAVFCSPEPPAKTST-----------PEDFIRMTKGITMATAKAVAAGNS-----CRQEDVIATANLSRRAIADMLRACKEAAYHPEVAPDVRLRALHYGRECANGYLELLDHVLLTLQKPSPELK 2266
BLAST of Talin-1 vs. Ensembl Human
Match: TLN2 (talin 2 [Source:HGNC Symbol;Acc:HGNC:15447]) HSP 1 Score: 940.258 bits (2429), Expect = 0.000e+0 Identity = 717/2424 (29.58%), Postives = 1234/2424 (50.91%), Query Frame = 1
Query: 49 FELRIHIVDADVTKIVPLDPEATIFQLCETIRKNIREAQTKSPKSYGLYLPHDDLKKGLWLDNSKTLQHYILKRGDTIEYRNRSRWLHIRTMDGTNKTLKVDDSWTVSELMLTVCTKLGIYNYDEYSLISDKMDFSPGIDKTLSMKRGISINXXXXXXXXXXXXYHTEDGLNWLNPSQSLRQQGIEESEVLLLKRKYFFSDMNVDSRDPIQLSLLYEQLKDAVINGTHPVTLPEAIELAGLQCQVQLGNYSADKFKPGFLDLRECLPKEYQKNPKTVEKKIFNQHSKSKDLSEVEAKEKYCLLCRSFKTYGITFFLVKEKVIGKNKLIPRLLGVNKESVVQVDEKTKEIINTWPLTSIRKWAASFNGFTMDFGEYSPDEYYTAQTDKGERISQLIAGYIDIILKRKKAKDHLGVDADEESIMYEENIAPSKAIIVEHVPKQKRSSVSEEDVVIRKKAHMANSSVRMNSQASDSVCSQDCTDFYQEDINMSRQTSSLGRTQSPSSSLTTNSMHY-RMSDDDIRQKLYIISLQDNLDTIQKYKDQLMIENKGPEIGKDEASQQWIYVNIDNSRQRMADEIGAMNAAVAQVLRSAQGLATIXXXXXXXXXXXXIAKMQNSFSLITVHLPSLMEEIRTAAYYQDQLTDEDVSGEELIAAAKRLADAFTNLIKAAYPVEDQKRSLNRKEIFDAANAVGEASSDLLQQITEQENCQIELKSERPYSIIMITEEDQLYQEELLRLAKSVANETTNLIKQVKVIAVEAENPSDQKKVVMAATETGLAISQLISTTKIVAPTIEQSVCQEQLIFSIEDVSKAIQVVVESSNKATQSEELQDLTVQAANQVQEALDTLMKHLRXXXXXXXXXXXXXXAYENI----QEXXXXXXXXXXXXXXXRRLAQATTAMISEIQLKAVNEQYKTPEERDKLINAAKQLAEATTVLIDSAKNCTMDKDEMNLRYTLREATERFIVVTYTTECATYIQEQVIDHLLVAARKAATTGTHLINTSLSAA--KKSRASNFKVCNDGRELSNQISNLIVAIKEARRDPKDHLAQLELIAACRDYIDPSEQLSQSNKYMWPTVSDPSLQTALNQSINQSVIATEELKKCVHQADLMCQHLDLSAALEQLKRLEQNLKSIKNSIERENLIPLPDEKSDESAALLIKSVRRSGSAANQFKNDLESRCVVYEQTNGEDSYQNLENLDVAGQKARELSMALDRLVHAARGVAASIEFENQESENNDKNLEKLAQLQIVNNCLEAVKAARDLVIEAKS---SPPDNDQMDRAQQASVRXXXXXXXXXXXXPGQRDLDMLSKHIESKKHQFAENRLPIQQNNNINLSNCRSELTDTTFDFNQAVNELVSAPSFNLVNKGCKKMRMSYDRIVEICNVLVHDPFDESDSALHHLSSNRDHIANGVMI------MSEDCQTLLDKVKKIQCEPDNIIVRKQLQEATKMLLDSINRLLTNISTNLRPGQKECDKTIYRLESMRPILDNPVHPISHKDYFECLDFIIDKTVQPLADSLKNIPAAVKDENNQKFIDSIYHCADSVCMLLEETAQTAYLVGVGDVRSKIGNKGLADHTSFLQIQKEISENCQTICNPDTTARQDSSLMISTAGQIAENSRKLCEASK--TIMISFPNDKIKLSDKTKITLLAVSELMTGVQNLNQNFNEDNRKEVESLSGKVQDNVAELVQLLLSYKFAGDAAIISEEAKESQGPIKAAGITVLDTAIEVIQCSKALISSEANEELFIAYSSSCKDLNDALKHLISTIKESAPGQKECDEXXXXXXXXXXQAYDSKMKIMKHRSRTISRTFESEESYQNILQSALIQMPHCINELSRAGKKEPEQLARIFSRQTQLLESMVNSCICAANQTDLIQNSNIYLEHLITILEASEQLLKAVKKSGGNPKANSVHSQIDEMAQGVIESCEDLLAALDKISFKQGNVNTIVETITKSSAKVQESAIIPEKSRFGNSQSKMLDICYDMNNLTTDISSNANSESTQRLLAPLTQNLTQRYDDLCRACQGAVATLSNENNGKQLQECVQTVGKVSISLVK--STTEVRPSVASSISNLQAKTQELHKRIDDVIQLLISSNVGTQACTQAIKILKEINSDIDTSILFVKSADIQNDDREYYSVKELFKKSRNSVIDNSSELVRNIKLIVSKDVCDVNILQESADQIAITSQSLANDVKVGLEHLNSSTSQYNIELLVSFQEVIVSLISFLEVARNTSGLPYTDPLFQNLKEEGKCSINAITSLLKVLKSMDDVNLKDFQAIDNAIIXXXXXXXXXXXXXXGISREASPVESPTSTNRLSIGSDITVSPRFAPEEINRLIPSLANVCDKILEISSPEFKPIIRQENISVVSISCSKVNNELTSACKNLLRNGPVTDS-KKQTLNTVDQLVENYTELLKNFKLYLTNPTKE 7257
L+I + +V K + +P ++ C IR+ + EAQT YGL+L +D +KG+WL+ +TL +Y+L+ GD +EY+ + R IR +DG+ KT+ VDDS TV EL++T+C+++GI NY+EYSLI + ++ + T ++K+ ++ +D+ K++KLK K HT+D LNWL+ S++ R+QG++E+E LLL+RK+F+SD NVDSRDP+QL+LLY Q +D ++NG+HPV+ +A E G Q Q+Q G + K KPGFLDL+E LPKEY K + EK+IF +H ++SE+EAK KY L RS +TYG++FFLVKEK+ GKNKL+PRLLG+ K+SV++VDEKTKE++ WPLT++++WAAS FT+DFGEY + YY+ QT +GE+ISQLIAGYIDIILK+K++KD G++ DEES M EE+++P K+ I++ + R+ +E V + SS +T ++G SP + MH M Q+ + ++ ++ +Q+ +D L + P +G+D AS+ W+ +D S+ + ++ A+ A A V+ G + + + + + I+ +L + + ++ A D DE SGE+L+ AA+ LA A ++L+KA P + R + + AA ++G+AS DLL+QI E E D+ +Q+ L+ LAK+VAN L+ + K +A AE+ Q +V+ AAT+ L+ SQL++ K+V+PTI VCQEQLI + + V ++++ V + AT EL AA+ V +AL L++H+R+ + + + + A + I + + S D ++V AR LAQAT+ +++ ++ A E E KL+ AAK LA++T ++++AK + + + + LREA E V T I++++++ L VAA++AA T I S +AA K+ A+ ++ + +++ I L+ ++ ++ +D AQL LI + ++++ P ++ S K PTVSD + L+Q + EL+ +A C +++ +AL ++ L+ L+ K + L PLP E ++ A L + + GS+ Q C G + Y G ARE + AL L AARGVAAS + A ++++ + ++ + L+ EAK +P D ++ R Q + +S +L+ C++ LPGQ+D+D+ K I + + LP + +SEL D NQ+ E+V A + S D FDE A ++ + + + +S LL K + +P + L A + + +SIN+L+T + T PGQKECD + LE+++ +LDNP P+S YF+C++ +++ + + L +S+ I K + F + + + ++C L E AQ AYLVG+ D S+ G++GL D F + + I CQ + +P ++ Q ++S A +A+++ LC A + + + P K K + + L+ ++ L+ +F+EDNR + + + + V L + +F A IS E ++Q PI + T+L+++ +I+ +++L + + + + ++D++K LI++I++ APGQ+ECD ++ + + I+ + + + T R S E+ Q L S + ++ H I+ ++ A + E QL ++ E ++ + + A++ Q L+ T+ E++ Q+L A K+ GGNPKA H I E AQ + E+ +D++ L++ + + G V +V+ I ++ +K+ E K F + Q+ ++ Y T S + L L +T Y L Q A AT E G Q++ VQ +G I LV+ +V P+ + + L + + +++ V+ L + N GTQAC A + I +D+DT+I+F + + ++ E F R +++ + LV + KL+VS + L ++A A T LA VK+G L S + + L+ + ++V +L + + + P DP LK K + +TSLLK +K+++D + +A++ I I +E + +S + S +PEE R+ + K + + RQE++ + K +++ +ACK + V+D + + L + Y +LL++ + L PT E
Sbjct: 4 LSLKICVRHCNVVKTMQFEPSTAVYDACRVIRERVPEAQTGQASDYGLFLSDEDPRKGIWLEAGRTLDYYMLRNGDILEYKKKQRPQKIRMLDGSVKTVMVDDSKTVGELLVTICSRIGITNYEEYSLIQETIE-EKKEEGTGTLKKDRTLLRDERKMEKLKAKLHTDDDLNWLDHSRTFREQGVDENETLLLRRKFFYSDQNVDSRDPVQLNLLYVQARDDILNGSHPVSFEKACEFGGFQAQIQFGPHVEHKHKPGFLDLKEFLPKEYIKQ-RGAEKRIFQEHKNCGEMSEIEAKVKYVKLARSLRTYGVSFFLVKEKMKGKNKLVPRLLGITKDSVMRVDEKTKEVLQEWPLTTVKRWAASPKSFTLDFGEYQ-ESYYSVQTTEGEQISQLIAGYIDIILKKKQSKDRFGLEGDEESTMLEESVSPKKSTILQQ--QFNRTGKAEHGSVALPAVMRSGSS--------------------------GPETFNVGSMPSPQQQVMVGQMHRGHMPPLTSAQQALMGTINTSMHAVQQAQDDLSELDSLPPLGQDMASRVWVQNKVDESKHEIHSQVDAITAGTASVVNLTAG----------DPADTDYTAVGCAITTISSNLTEMSKGVKLLAALMD---DEVGSGEDLLRAARTLAGAVSDLLKAVQPTSGEPR----QTVLTAAGSIGQASGDLLRQIGENET-------------------DERFQDVLMSLAKAVANAAAMLVLKAKNVAQVAEDTVLQNRVIAAATQCALSTSQLVACAKVVSPTISSPVCQEQLIEAGKLVDRSVENCVRACQAATTDSELLKQVSAAASVVSQALHDLLQHVRQFASRGEPIGRYDQATDTIMCVTESIFSSMGDAGEMVRQARVLAQATSDLVNAMRSDA--EAEIDMENSKKLLAAAKLLADSTARMVEAAKGAAANPENEDQQQRLREAAEGLRVAT-NAAAQNAIKKKIVNRLEVAAKQAAAAATQTIAASQNAAVSNKNPAAQQQLVQSCKAVADHIPQLVQGVRGSQAQAEDLSAQLALIISSQNFLQPGSKMVSSAKAAVPTVSDQAAAMQLSQCAKNLATSLAELRTASQKAHEACGPMEIDSALNTVQTLKNELQDAKMAAVESQLKPLPGETLEKCAQDLGSTSKAVGSSMAQLLT-----CAA----QGNEHY--------TGVAARETAQALKTLAQAARGVAAS-------------TTDPAAAHAMLDSARDVMEGSAMLIQEAKQALIAPGDAERQQRLAQVAKAVSHSLNNCVNCLPGQKDVDVALKSIGESSKKLLVDSLP---PSTKPFQEAQSELNQAAADLNQSAGEVVHATRGQSGELAAASGKFS-------------DDFDEFLDAGIEMAGQAQTKEDQIQVIGNLKNISMASSKLLLAAKSLSVDPGAPNAKNLLAAAARAVTESINQLIT-LCTQQAPGQKECDNALRELETVKGMLDNPNEPVSDLSYFDCIESVMENS-KVLGESMAGISQNAKTGDLPAFGECVGIASKALCGLTEAAAQAAYLVGISDPNSQAGHQGLVDPIQFARANQAIQMACQNLVDPGSSPSQ----VLSAATIVAKHTSALCNACRIASSKTANPVAKRHFVQSAKEVANSTANLVKTIKALDGDFSEDNRNKCRIATAPLIEAVENLTAFASNPEFVSIPAQISSEGSQAQEPILVSAKTMLESSSYLIRTARSLAINPKDPPTWSVLAGHSHTVSDSIKSLITSIRDKAPGQRECDYSIDGINRCIRDIEQASLAAVSQSLAT--RDDISVEALQEQLTSVVQEIGHLIDPIATAARGEAAQLGHKVTQLASYFEPLILAAVGVASKILDHQQQMTVLDQTKTLAESALQMLYAAKEGGGNPKAQHTHDAITEAAQLMKEAVDDIMVTLNEAASEVGLVGGMVDAIAEAMSKLDEGTPPEPKGTFVDYQTTVVK--YSKAIAVTAQEMMTKSVTNPEELGGLASQMTSDYGHLAFQGQMAAATAEPEEIGFQIRTRVQDLGHGCIFLVQKAGALQVCPTDSYTKRELIECARAVTEKVSLVLSALQAGNKGTQACITAATAVSGIIADLDTTIMFATAGTLNAEN------SETFADHRENILKTAKALVEDTKLLVSGAASTPDKLAQAAQSSAATITQLAEVVKLGAASLGSDDPETQVVLINAIKDVAKALSDLISATKGAASKPVDDPSMYQLKGAAKVMVTNVTSLLKTVKAVEDEATRGTRALEATI--------------ECIKQELTVFQSKDVPEKTS-----------SPEESIRMTKGITMATAKAVAAGNS-----CRQEDVIATANLSRKAVSDMLTACKQASFHPDVSDEVRTRALRFGTECTLGYLDLLEHVLVILQKPTPE 2265
BLAST of Talin-1 vs. Ensembl Human
Match: MAST4 (microtubule associated serine/threonine kinase family member 4 [Source:HGNC Symbol;Acc:HGNC:19037]) HSP 1 Score: 651.358 bits (1679), Expect = 0.000e+0 Identity = 312/555 (56.22%), Postives = 401/555 (72.25%), Query Frame = 1
Query: 9565 IKPRSQSLNPCRSPGAYEQDIFILNHVYKERFPKATIQMMERLSAMLEELENENTVSW-EPISRLVHTQIMKHVKDILNMTNLEAITSTYFFELTQNLEKLLKETRLKCPES-LARVRPIVQHLLFIIARPARLLECIEFDPKEFYKLLEVAENNLR---NVQTDVPKYIISKLGLDKDPYDIGSEELNTSLELNGGSLEIXXXXXXXXXXXXXXXXXLNMSQESNNSLELSFSKSMTPKESDFEDIKLISNGAYGAVHLVREKKTKKRFAMKKIRKDNLLLRNQVEQIFAERDIMTFADSPFVVGLYCTFETRKYLCMIMEYVEGGDVATLIKSIGPLPDELARMYFAETVLALEYLHNFGIVHRDLKPDNLLITLEGHIKLTDFGLSKVGLMNLTTTLLESVLNKDCTMFQDKQVFGTPDYIAPEVILRQGYDKMIDWWAMGIILYEFIVGCTPFYGDSTEELFGNIISGEIEWPQDPDPCVPDNAVNLITELLKRDPLVRLGAEGTHEVKEHEFFSDVDWQGLLRQKALFIPVLDHEDDTSYFDPRTSRYQH 11214
++PRS+SL+P RSP + +I ++NHVYKERFPKAT QM ERL ++ +N + + + H QI++ +D L+ ++ ITS YF EL L+KLL+E + LA ++ +V+ +L +IARPARLLEC+EFDP+EFY LLE AE + + ++TD+P+YIIS+LGL+KDP EE+ + G+ E + ES +S S P+ESDFE IKLISNGAYGAV+ VR K++++RFAMKKI K NL+LRNQ++Q F ERDI+TFA++PFVV +YC+FETR++LCM+MEYVEGGD ATL+K++GPLP ++ARMYFAETVLALEYLHN+GIVHRDLKPDNLL+T GHIKLTDFGLSKVGLM++TT L E + KD F DKQV GTP+YIAPEVILRQGY K +DWWAMGIILYEF+VGC PF+GD+ EELFG +IS EI WP+ D P +A +LIT LL+++PL RLG G +EVK+H FF +DW LLRQKA FIP L+ EDDTSYFD R+ +Y H
Sbjct: 160 MRPRSRSLSPGRSPACCDHEIIMMNHVYKERFPKATAQMEERLKEIITSYSPDNVLPLADGVLSFTHHQIIELARDCLDKSHQGLITSRYFLELQHKLDKLLQEAHDRSESGELAFIKQLVRKILIVIARPARLLECLEFDPEEFYYLLEAAEGHAKEGQGIKTDIPRYIISQLGLNKDPL----EEMAHLGNYDSGTAETPE------------------TDESVSSSNASLKLRRKPRESDFETIKLISNGAYGAVYFVRHKESRQRFAMKKINKQNLILRNQIQQAFVERDILTFAENPFVVSMYCSFETRRHLCMVMEYVEGGDCATLMKNMGPLPVDMARMYFAETVLALEYLHNYGIVHRDLKPDNLLVTSMGHIKLTDFGLSKVGLMSMTTNLYEGHIEKDAREFLDKQVCGTPEYIAPEVILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVISDEINWPEK-DEAPPPDAQDLITLLLRQNPLERLGTGGAYEVKQHRFFRSLDWNSLLRQKAEFIPQLESEDDTSYFDTRSEKYHH 691 HSP 2 Score: 109.768 bits (273), Expect = 1.266e-22 Identity = 48/99 (48.48%), Postives = 69/99 (69.70%), Query Frame = 1
Query: 12130 IVIHRRSRNFGFVIRAIRVFYGESNVYTLHHLIVGVDPEGSAFQAGLREGDLITHINGVSIVGAYHTEVVSMIIQSGASISLRVIPINKSFIRTDGPWR 12426
IVIH +N+GF IRAIRV+ G+S++YT+HH++ V+ A QAGL+ GDLITHING + G HTEV+ ++++SG +S+ P + I+T GP R
Sbjct: 953 IVIHSSGKNYGFTIRAIRVYVGDSDIYTVHHIVWNVEEGSPACQAGLKAGDLITHINGEPVHGLVHTEVIELLLKSGNKVSITTTPFENTSIKT-GPAR 1050
BLAST of Talin-1 vs. Ensembl Human
Match: MAST4 (microtubule associated serine/threonine kinase family member 4 [Source:HGNC Symbol;Acc:HGNC:19037]) HSP 1 Score: 651.358 bits (1679), Expect = 0.000e+0 Identity = 312/555 (56.22%), Postives = 401/555 (72.25%), Query Frame = 1
Query: 9565 IKPRSQSLNPCRSPGAYEQDIFILNHVYKERFPKATIQMMERLSAMLEELENENTVSW-EPISRLVHTQIMKHVKDILNMTNLEAITSTYFFELTQNLEKLLKETRLKCPES-LARVRPIVQHLLFIIARPARLLECIEFDPKEFYKLLEVAENNLR---NVQTDVPKYIISKLGLDKDPYDIGSEELNTSLELNGGSLEIXXXXXXXXXXXXXXXXXLNMSQESNNSLELSFSKSMTPKESDFEDIKLISNGAYGAVHLVREKKTKKRFAMKKIRKDNLLLRNQVEQIFAERDIMTFADSPFVVGLYCTFETRKYLCMIMEYVEGGDVATLIKSIGPLPDELARMYFAETVLALEYLHNFGIVHRDLKPDNLLITLEGHIKLTDFGLSKVGLMNLTTTLLESVLNKDCTMFQDKQVFGTPDYIAPEVILRQGYDKMIDWWAMGIILYEFIVGCTPFYGDSTEELFGNIISGEIEWPQDPDPCVPDNAVNLITELLKRDPLVRLGAEGTHEVKEHEFFSDVDWQGLLRQKALFIPVLDHEDDTSYFDPRTSRYQH 11214
++PRS+SL+P RSP + +I ++NHVYKERFPKAT QM ERL ++ +N + + + H QI++ +D L+ ++ ITS YF EL L+KLL+E + LA ++ +V+ +L +IARPARLLEC+EFDP+EFY LLE AE + + ++TD+P+YIIS+LGL+KDP EE+ + G+ E + ES +S S P+ESDFE IKLISNGAYGAV+ VR K++++RFAMKKI K NL+LRNQ++Q F ERDI+TFA++PFVV +YC+FETR++LCM+MEYVEGGD ATL+K++GPLP ++ARMYFAETVLALEYLHN+GIVHRDLKPDNLL+T GHIKLTDFGLSKVGLM++TT L E + KD F DKQV GTP+YIAPEVILRQGY K +DWWAMGIILYEF+VGC PF+GD+ EELFG +IS EI WP+ D P +A +LIT LL+++PL RLG G +EVK+H FF +DW LLRQKA FIP L+ EDDTSYFD R+ +Y H
Sbjct: 349 MRPRSRSLSPGRSPACCDHEIIMMNHVYKERFPKATAQMEERLKEIITSYSPDNVLPLADGVLSFTHHQIIELARDCLDKSHQGLITSRYFLELQHKLDKLLQEAHDRSESGELAFIKQLVRKILIVIARPARLLECLEFDPEEFYYLLEAAEGHAKEGQGIKTDIPRYIISQLGLNKDPL----EEMAHLGNYDSGTAETPE------------------TDESVSSSNASLKLRRKPRESDFETIKLISNGAYGAVYFVRHKESRQRFAMKKINKQNLILRNQIQQAFVERDILTFAENPFVVSMYCSFETRRHLCMVMEYVEGGDCATLMKNMGPLPVDMARMYFAETVLALEYLHNYGIVHRDLKPDNLLVTSMGHIKLTDFGLSKVGLMSMTTNLYEGHIEKDAREFLDKQVCGTPEYIAPEVILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVISDEINWPEK-DEAPPPDAQDLITLLLRQNPLERLGTGGAYEVKQHRFFRSLDWNSLLRQKAEFIPQLESEDDTSYFDTRSEKYHH 880 HSP 2 Score: 109.768 bits (273), Expect = 1.525e-22 Identity = 48/99 (48.48%), Postives = 69/99 (69.70%), Query Frame = 1
Query: 12130 IVIHRRSRNFGFVIRAIRVFYGESNVYTLHHLIVGVDPEGSAFQAGLREGDLITHINGVSIVGAYHTEVVSMIIQSGASISLRVIPINKSFIRTDGPWR 12426
IVIH +N+GF IRAIRV+ G+S++YT+HH++ V+ A QAGL+ GDLITHING + G HTEV+ ++++SG +S+ P + I+T GP R
Sbjct: 1142 IVIHSSGKNYGFTIRAIRVYVGDSDIYTVHHIVWNVEEGSPACQAGLKAGDLITHINGEPVHGLVHTEVIELLLKSGNKVSITTTPFENTSIKT-GPAR 1239
BLAST of Talin-1 vs. Ensembl Human
Match: MAST4 (microtubule associated serine/threonine kinase family member 4 [Source:HGNC Symbol;Acc:HGNC:19037]) HSP 1 Score: 650.973 bits (1678), Expect = 0.000e+0 Identity = 312/555 (56.22%), Postives = 401/555 (72.25%), Query Frame = 1
Query: 9565 IKPRSQSLNPCRSPGAYEQDIFILNHVYKERFPKATIQMMERLSAMLEELENENTVSW-EPISRLVHTQIMKHVKDILNMTNLEAITSTYFFELTQNLEKLLKETRLKCPES-LARVRPIVQHLLFIIARPARLLECIEFDPKEFYKLLEVAENNLR---NVQTDVPKYIISKLGLDKDPYDIGSEELNTSLELNGGSLEIXXXXXXXXXXXXXXXXXLNMSQESNNSLELSFSKSMTPKESDFEDIKLISNGAYGAVHLVREKKTKKRFAMKKIRKDNLLLRNQVEQIFAERDIMTFADSPFVVGLYCTFETRKYLCMIMEYVEGGDVATLIKSIGPLPDELARMYFAETVLALEYLHNFGIVHRDLKPDNLLITLEGHIKLTDFGLSKVGLMNLTTTLLESVLNKDCTMFQDKQVFGTPDYIAPEVILRQGYDKMIDWWAMGIILYEFIVGCTPFYGDSTEELFGNIISGEIEWPQDPDPCVPDNAVNLITELLKRDPLVRLGAEGTHEVKEHEFFSDVDWQGLLRQKALFIPVLDHEDDTSYFDPRTSRYQH 11214
++PRS+SL+P RSP + +I ++NHVYKERFPKAT QM ERL ++ +N + + + H QI++ +D L+ ++ ITS YF EL L+KLL+E + LA ++ +V+ +L +IARPARLLEC+EFDP+EFY LLE AE + + ++TD+P+YIIS+LGL+KDP EE+ + G+ E + ES +S S P+ESDFE IKLISNGAYGAV+ VR K++++RFAMKKI K NL+LRNQ++Q F ERDI+TFA++PFVV +YC+FETR++LCM+MEYVEGGD ATL+K++GPLP ++ARMYFAETVLALEYLHN+GIVHRDLKPDNLL+T GHIKLTDFGLSKVGLM++TT L E + KD F DKQV GTP+YIAPEVILRQGY K +DWWAMGIILYEF+VGC PF+GD+ EELFG +IS EI WP+ D P +A +LIT LL+++PL RLG G +EVK+H FF +DW LLRQKA FIP L+ EDDTSYFD R+ +Y H
Sbjct: 155 MRPRSRSLSPGRSPACCDHEIIMMNHVYKERFPKATAQMEERLKEIITSYSPDNVLPLADGVLSFTHHQIIELARDCLDKSHQGLITSRYFLELQHKLDKLLQEAHDRSESGELAFIKQLVRKILIVIARPARLLECLEFDPEEFYYLLEAAEGHAKEGQGIKTDIPRYIISQLGLNKDPL----EEMAHLGNYDSGTAETPE------------------TDESVSSSNASLKLRRKPRESDFETIKLISNGAYGAVYFVRHKESRQRFAMKKINKQNLILRNQIQQAFVERDILTFAENPFVVSMYCSFETRRHLCMVMEYVEGGDCATLMKNMGPLPVDMARMYFAETVLALEYLHNYGIVHRDLKPDNLLVTSMGHIKLTDFGLSKVGLMSMTTNLYEGHIEKDAREFLDKQVCGTPEYIAPEVILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVISDEINWPEK-DEAPPPDAQDLITLLLRQNPLERLGTGGAYEVKQHRFFRSLDWNSLLRQKAEFIPQLESEDDTSYFDTRSEKYHH 686 HSP 2 Score: 109.768 bits (273), Expect = 1.320e-22 Identity = 48/99 (48.48%), Postives = 69/99 (69.70%), Query Frame = 1
Query: 12130 IVIHRRSRNFGFVIRAIRVFYGESNVYTLHHLIVGVDPEGSAFQAGLREGDLITHINGVSIVGAYHTEVVSMIIQSGASISLRVIPINKSFIRTDGPWR 12426
IVIH +N+GF IRAIRV+ G+S++YT+HH++ V+ A QAGL+ GDLITHING + G HTEV+ ++++SG +S+ P + I+T GP R
Sbjct: 948 IVIHSSGKNYGFTIRAIRVYVGDSDIYTVHHIVWNVEEGSPACQAGLKAGDLITHINGEPVHGLVHTEVIELLLKSGNKVSITTTPFENTSIKT-GPAR 1045
BLAST of Talin-1 vs. Ensembl Celegans
Match: tln-1 (TaLiN [Source:UniProtKB/TrEMBL;Acc:A0A0K3AUD9]) HSP 1 Score: 731.095 bits (1886), Expect = 0.000e+0 Identity = 670/2512 (26.67%), Postives = 1181/2512 (47.01%), Query Frame = 1
Query: 43 GNFELRIHIVDADVTKIVPLDPEATIFQLCETIRKNIREAQTKSPKSYGLYLPHDDLKKGLWLDNSKTLQHYILKRGDTIEYRNRSRWLHIRTMDGTNKTLKVDDSWTVSELMLTVCTKLGIYNYDEYSLISD--------------------------KMDFSPGIDKTLSMKRGISINXXXXXXXXXXXXYHTEDGLNWLNPSQSLRQQGIEESEVLLLKRKYFFSDMNVDSRDPIQLSLLYEQLKDAVINGTHPVTLPEAIELAGLQCQVQLGNYSADKFKPGF-LDLRECLPKEYQKNPKTVEKKIFNQHSKSKDLSEVEAKEKYCLLCRSFKTYGITFFLVKEKVIGKNKLIPRLLGVNKESVVQVDEKTKEIINTWPLTSIRKWAASFNGFTMDFGEYSPDEYYTAQTDKGERISQLIAGYIDIILKRKKAKDHLGVDADEESIMYEENIAPSKAIIVEHVPKQKRSSVSEEDVVIRK--KAHMANSSVRMNSQASDSVCSQDCTDFYQEDINMSRQTSSLGRTQSPSSSLTTNSMHYRMSDDDIR---QKLYIISLQDNLDTIQKYKDQLMIENK--GPEIGKDEASQQWI----YVNIDNSRQRMADEIGAMNAAVAQVLRSAQGLATIXXXXXXXXXXXXIAKMQNSFSLITVHLPSLMEEIRTAAYYQDQLTDEDVSGEELIAAAKRLADAFTNLIKAAYPVEDQKRSLNRKEIFDAANAVGEASSDLLQQITEQENCQIELKSERPYSIIMITEEDQLYQEELLRLAKSVANETTNLIKQVKVIAVEAENPSDQKKVVMAATETGLAISQLISTTKIVAPTIEQSVCQEQLIFSIEDVSKAIQVVVESSNKAT-QSEELQDLTVQAANQVQEALDTLMKHLRXXXXXXXXXXXXXXAYENIQEXXXXXXXXXXXXXXXRRLAQATTAMISEIQLKAVNEQYKTPEERDKLINAAKQLAEATTVLIDSAKNCTMDKDEMNLRYTLREATERFIVVTYTTECATYIQEQ-VIDHLLVAARKAATTGTHLINTSLSAAK--KSRASNFKVCNDGRELSNQISNLIVAIKEARR---DPKDHL-AQLELIAACRDYIDPSEQLSQSNKYMWPTVSDPSLQTALNQSINQSVIATEELKKCVHQADLMCQHLDLSAAL----EQLKRLEQNL-KSIKNSIERENLIPLPDEKSDESAALLIKSVRRSGSAANQFKNDLESRCVVYEQTNGEDSYQNLENLDVAGQKARELSMALDRLVHAARGVAASIEFENQESENNDKNLEKLAQLQIVNNCLEAVKAARDLVIEAKSSPPDNDQMDRAQQASVRXXXXXXXXXXXXPGQRDLDML--SKHIESKKHQFAENRLPIQQNNNINLSNCRSELTDTTFDFNQAVNELVSAPSFNLVNKGCKKMRMSYDRIVEICNVLVHDPFDESDSALHHL--SSNRDHIANGVMIMSEDCQ----TLLDKVKKIQCEPDNIIVRKQLQEATKMLLDSINRL--LTNISTNLRPGQKECDKTIYRLESMRPILDNPVHPISHKDYFECLDFIIDKTVQPLADSLKNIPAAVKDENNQKFIDSIYHCADSVCMLLEETAQTAYLVGVGDVRSKIGNKGLADHTSFLQIQKEISENCQTICNPDTTARQ-DSSLMISTAGQIAENSRKLCEASKTI--MISFPNDKIKLSDKTKITLLAVSELMTGVQNLNQNFNEDNRKEVESLSGKVQDNVAELVQLLLSYKFAGDAAIISEEAKESQGPIKAAGITVLDTAIEVIQCSKALISSEANEELFIAYSSSCKDLNDALKHLISTIKESAPGQKECDEXXXXXXXXXXQAYDSKM------KIMKHRSRTISRTFESEESYQNILQSALIQMPHCINELSRAGKKEPEQLARIFSRQTQLLESMVNSCICAANQT-DLIQNSNIYLEHLITILEASEQLLKAVKKSGGNPKANSVHSQIDEMAQGVIESCEDLLAALDKISFKQGNVNTIVETITKSSAK--VQESAIIPEKSRFGNSQSKMLDICYDMNNLTTDISSNANSESTQRLLAPLTQNLTQRYDDLCRACQGAVATLSNENNGKQLQECVQTVGKVSISLVKSTTEVR--PSVASSISNLQAKTQELHKRIDDVIQLLISSNVGTQACTQAIKILKEINSDIDTSILFVKSADI-QNDDREYYSVKELFKKSRNSVIDNSSELVRNIKLIVSKDVCDVNILQESADQIAITSQSLANDVKVGLEHLNSSTSQYNIELLVSFQEVIVSLISFLEVARNTSGLPYTDPLFQNLKEEGKCSINAITSLLKVLKSMDDVNLKDFQAIDNAIIXXXXXXXXXXXXXXGISREASPVESPTSTNRLSIGSDITVSPRFAPEEINRLIPSLANVCDKILEISSPEFKPIIRQENISVVSISCSKVNNELTSACKNLLRNGPVTDSKKQTLNTVDQLVENYTELLKNFKLYLT-NPTKE--TRIPVET---VVSKLNELIKLLRDQVNL 7332
G L + + + K + +P I+ + IR+ + YG++ ++ K LW+DN +T +HY+++ D IEY+ + R L +R +DG KT+ VD+S VS+LM+TVC K+GI NY+EYSL+ D K S D+ G K+++KL++L+KK HT++ L WL+ +++LR+QGI E E L+L+RKYFFSD NVDSRDP+QL+LLY Q +D ++ G HPV A +LA LQ +Q G++ DK P F LD R+ LPKEY KN K EKK+ + + SE++AK KY LCR KTYG+TFF+VKEK+ GKNKL+PRLLGVNKESV++VDE +K+I+ WPL +R+W S F++DFG+Y D YY+ QT GE+I+QLI GY+DIILK+K+ +DH G++ DE S M E+ +AP+KA +V H ++ V +R + +N +V + + QE L R Q R+ D+ Q+ I +++ + ++ + +L E + P D + +W+ VN +N +R+A AM AA AQV++ EE ++ + + I +LP + +R + + D L+ A K+L AF + P E + R R E+F A VGE S L+ + E N E Q + E L++ AK+VA T L+ K I+ E + P Q++V+ +AT+ A SQL++ ++VAPTI+ + CQ+QL + +V++++ ++ + A Q L D+ +AA QV ALD+L++H + Y + + R A+ + + +E ++ PE R++L++AA ++A AT+ +I + + ++ Y LR A ER V T E QEQ ++ L AA++ A T I+ + SA +SR+ + + + + + NLI +I+E+++ P + AQ LI ++ S +L ++ + P VSD L ++L+QS N+ + +L+ V+ A Q L+ S L E +K L+ L + K +I RE L P+ + S ++ L+ + GS Q + T+ +D Y +++A Q R+ + A+ +V + D L+KL + +AR +V E+ DR ++ S + S ++ + L +KHIE H+ IQ + +N R + QA N+ + A S +V G R E ++ V D S + L SN +++ ++ E+ Q +L+ +++ P + + +Q T+ L ++N+L L+ + Q+ECD + R++++ + + P++ YF L + D + + L +++ + K + + F S+ AD++C L E + +AYLVG+ S G L D + + + I+ +CQ + +RQ + ++S I + S L + + PN K L S L+T ++L++ + ++R S + +++ +L+ FA IS E +Q PI + +LD++ ++IQ +K+ S+ +E + + + + ++D++ L++ I E+APGQ E + A+ L+ L Q S M + KH + +E +Q Q+ +++L A + E+L ++ Q++E + ++ CAA T D Q + ++ + T++EA ++ A ++SGGNP A H+ + + A + + D+ + K+S +QG V +V+TI+ S A V S+ P S F ++Q++M D+ ++ + ++ L + NL+++Y + + A L + G++L+ VQ +G I V R P L ++ + +R++ V+ L S++ GTQAC A + I D+DT+I+F S + +DDR++ S KE +++ + LV + K +V+ + L +A T +L++ VK G L+S S+ + ++ + ++V +L S ++ +N SGL P +LK+ K ++ + LLK + ++++ N + +A++ A+ +A E + L+ G+ I F PE + + ++ + ++++ + P +E I V ++S S V + L + + + + + L++ + N LL + + NP +E R+ +E V S L+ L+ L + L
Sbjct: 2 GVLSLTVSSAEKGIKKTMQFEPSTLIYDAAKLIREKF-AMHDVNANEYGIFRLDENPSKSLWMDNGRTFEHYLVRNKDEIEYKRKIRLLKVRMLDGAVKTISVDESQPVSQLMMTVCNKIGISNYEEYSLVRDDILMQNGGGGGGGGGQNGGSTWNLKEKESRSKSSDRGGGGIYGTMRKKNEQKLEELRKKLHTDEELPWLDHTKTLREQGITEEETLILRRKYFFSDSNVDSRDPVQLNLLYVQCRDGILRGLHPVEKETAFQLAALQSHIQYGDFPYDK--PKFHLDGRDVLPKEYAKN-KENEKKVVAMYKELSGTSELDAKSKYVHLCRGLKTYGVTFFVVKEKLPGKNKLVPRLLGVNKESVMRVDENSKQILKEWPLEQVRRWVPSAKCFSLDFGDYQ-DGYYSVQTTDGEKIAQLIQGYVDIILKKKRTQDHQGIEGDEGSTMLEDMVAPAKATLVAHGQIGSGQHATDGLVAVRGVLRTPQGGQGYGINGAQYGAVSGEITS---QE----------LARAQ-------------RLRYQDMYQHPQRALIGTIEATIRAVEDAEIELEAEPQIDIPRFNDDYSQNRWMEEQQAVNKENVNERLA----AMGAATAQVVQ-------------WTAVEEYDDRVGTAIATIGSNLPDVSRNVRDLGAFMEHRERGD-----LLDATKKLCGAFGKFLNTVNP-ETEAR---RNEVFRTAGHVGETSQHLI-NVMEAPN-----------------EGQQKFDERLVQSAKNVATSTAQLVLCAKTISAECDEPQVQERVIQSATKCAFATSQLVACARVVAPTIDNNACQQQLSTAATEVTQSVNNLLHDAEHAVYQQSSLTDIH-EAARQVTSALDSLLEHAKCSPKTQTTRREEEEMYNEVLRRTNRMVVHQGPSEDLTREARKVVRHSQLLTEQFQHEAHQRPEHRERLLDAAAKVAHATSEMILATEQAESQPRQVETEYALRTAAERLGQV--TNETTQEQQEQHIMQRLEQAAKQTAYDATQTISAANSAKDVIESRSYKENLVYESTQTAGHLPNLITSIRESQKVDNTPGEKFKAQSRLIRDSYKVLETSVRLFETARTAVPMVSDSHLASSLDQSANRLGTSLADLRTSVNDA----QQLNFSQQLLYSEELIKELDDQLVNTQKRAIARE-LPPIQNATSFSVSSKLMATTSNVGSGVAQL--------ITAAATSNDDKYVGTSAVELA-QGLRDFTDAITEIV----------------TVRTDIQLDKL------------IVSARSVVHESGRV------FDRVREKSAPTVLTDAAMNVSTSLKQVISCLPDTKHIEKAIHE-------IQTAHTS--ANIRP------MEVRQAANKFIEATSQLVVTIGSPDSR-------EAVDIFVRAYCDLHGSVVAQLQRQSNMNNVKTAIIDRLEEAQRGSIGVLETLRQA-GNPSDHTLSQQFTSKTRELATTVNQLVELSGMDGGESRWQRECDAALRRIQAVYHVTQHANVPLNDNGYFASLQSVSDGS-RRLGEAMTGMARHAKGNDTEGFCTSVRDSADALCSLAESASHSAYLVGISHPASSPGRAALIDSSEVARSVESINASCQRV-----ESRQLNREELMSDISSITKQSSSLAQLCRIASEKTQNPNVKKHLVGCAMGVASKTSSLVTAFKDLDRMPDAESR--CTSSASELRQVALQLLHFADKPDFAAIQGSISTEGHSAQQPILQSSREMLDSSAQMIQTAKSWASAPQDEATWQRMAVNSRQVSDSIMRLVNAIHEAAPGQMELEAAIGRLSALSGQIERSAMDCYASGNVQKHGA-------NAERQLLQQVQHIASQLEDKVDDLHNAAVEHGERLPKVVQLHCQMVEDLADAACCAAGMTVDSNQQTELF-DKCKTVVEAELAMMVASRESGGNPNAVHAHANVKDAAGQLKHAIGDMRQTIAKVSSEQGAVQGMVDTISSSIAHTDVAVSSAHP-GSSFADAQTRMTAYLEDIRRTAIEMPTLNTTD-----LGAASLNLSEKYRLVAGDVRQAAGMLPEADIGQRLKLAVQKLGTSCIETVTVAGGKRAHPEDERIQRQLSSQAGTVVERVEQVLAALHSASRGTQACINAANTVSGIIGDLDTTIMFATSGSLNSSDDRKFPSHKE-------AIVKTAKALVEDTKALVAGAASNQEQLAVAAQNAVRTIVNLSDAVKTGAVSLSSENSETQVLVIHAVRDVAAALTSLIQATKNASGLSLQHPAMGHLKDAAKVMVSNVARLLKTVATVEEKNQQGTRAVEAAV-------------------DAIGFEMKQFEHDLNEGAAIPTD--FRPEHLQQTAEHVSEITKRVMQGADA---PQSEEEIIGVANLSRSAVRS-LLAVVRTISNDADTAPQRYAVLDSGRDVANNVKSLLVSLHTQMVRNPGQEESRRLLLEASKGVSSALSHLVGLCNEMTGL 2310
BLAST of Talin-1 vs. Ensembl Celegans
Match: kin-4 (KIN-4 protein; Protein KINase [Source:UniProtKB/TrEMBL;Acc:G5EFA4]) HSP 1 Score: 533.872 bits (1374), Expect = 3.643e-157 Identity = 263/503 (52.29%), Postives = 350/503 (69.58%), Query Frame = 1
Query: 9748 SRLVHTQIMKHVKDILNMTNLEAITSTYFFELTQNLEKLLKETRLKC-PESLARVRPIVQHLLFIIARPARLLECIEFDPKEFYKLLEVAENNLRNVQT-------DVPKYIISKLGLDKDPYDIGSEELNTSLELNGGSLEIXXXXXXXXXXXXXXXXXLNMSQESNNSLELSFSKSMTPKESDFEDIKLISNGAYGAVHLVREKKTKKRFAMKKIRKDNLLLRNQVEQIFAERDIMTFADSPFVVGLYCTFETRKYLCMIMEYVEGGDVATLIKSIGPLPDELARMYFAETVLALEYLHNFGIVHRDLKPDNLLITLEGHIKLTDFGLSKVGLMNLTTTLLESV-LNKDCTMFQDKQVFGTPDYIAPEVILRQGYDKMIDWWAMGIILYEFIVGCTPFYGDSTEELFGNIISGEIEWPQDPDPCVPDNAVNLITELLKRDPLVRLGA-EGTHEVKEHEFFSDVDWQGLLRQKALFIPVLDHEDDTSYFDPRTSRYQHESES 11226
+R +H QI++ D L + + IT +YF E++Q LE+ L E ++K PESL + +V+ LL I++RPARLLEC+EFDP EFY LLE AE +R D+P+YII KLGLD+DP +E +++S + + T + + QE+N + P E DF+ I+L+SNGAYGAV+LVR ++T++RFA+KK+ K L+LRNQV+Q+FAERDI+T AD+PFVV Y +FETR+YLCM+MEYVEGGD A L+KS G LP EL R+Y AET+LA+EYLH++GIVHRDLKPDNLLIT GHIKLTDFGLSK+GLMN TT + E + FQDKQ+ GTP+YIAPEVILR+GY K +DWWA+GIILYEF+VG PF+G++ E LF +IS ++E+P++ D +P A +L LL+++P RLG G ++ HEFF +D+ LLRQKA F+P LD+E+DTSYFD RT RY HE+ES
Sbjct: 392 TRFLHHQIVEIALDCLGKSKDDLITCSYFCEMSQRLEETLNEAQMKTSPESLEYLSKLVKKLLMIVSRPARLLECLEFDPDEFYHLLEEAEGVVREQLGSGTARVPDLPQYIIGKLGLDRDPLIDSTEHVDSSENTHATT-----------SGTTSAKGAGSAWQETNRA----------PCEDDFDTIRLVSNGAYGAVYLVRHRETRQRFALKKMNKQTLMLRNQVDQVFAERDILTMADNPFVVSFYGSFETRQYLCMLMEYVEGGDCAALLKSAGTLPVELVRLYVAETILAIEYLHSYGIVHRDLKPDNLLITAMGHIKLTDFGLSKIGLMNRTTLVAEGYDAVVETQQFQDKQLCGTPEYIAPEVILRRGYGKPVDWWALGIILYEFLVGIVPFFGETPEALFSKVISEDVEYPEE-DEALPPEAADLCRRLLEKNPAERLGTLNGAAQLMAHEFFILLDFTSLLRQKAEFVPQLDNEEDTSYFDTRTDRYNHEAES 872 HSP 2 Score: 78.1814 bits (191), Expect = 1.499e-13 Identity = 39/115 (33.91%), Postives = 65/115 (56.52%), Query Frame = 1
Query: 12130 IVIHRRSRNFGFVIRAIRVFYGE-SNVYTLHHLIVGVDPEGSAFQAGLREGDLITHINGVSIVGAYHTEVVSMIIQSGASISLRVIPINKSFIRTDGPWRPAGKMATKHHPRKAQ 12471
I I + FGF ++++RV+ GE S YT+ H++ V AF A L+ D+ITH+NG + H +++ ++ +G + LR++P+ + IR R GKMA K P++ Q
Sbjct: 1173 ITIRKGPFGFGFTLKSVRVYLGEHSEYYTIEHIVTAVVEGSPAFHANLQAEDMITHVNGHPVHNLTHPQLMHRLLANGNELILRLVPLANTSIREGAARRTVGKMARK-KPKRPQ 1286
BLAST of Talin-1 vs. Ensembl Celegans
Match: kin-4 (KIN-4 protein; Protein KINase [Source:UniProtKB/TrEMBL;Acc:G5EFA4]) HSP 1 Score: 528.48 bits (1360), Expect = 7.039e-157 Identity = 263/503 (52.29%), Postives = 350/503 (69.58%), Query Frame = 1
Query: 9748 SRLVHTQIMKHVKDILNMTNLEAITSTYFFELTQNLEKLLKETRLKC-PESLARVRPIVQHLLFIIARPARLLECIEFDPKEFYKLLEVAENNLRNVQT-------DVPKYIISKLGLDKDPYDIGSEELNTSLELNGGSLEIXXXXXXXXXXXXXXXXXLNMSQESNNSLELSFSKSMTPKESDFEDIKLISNGAYGAVHLVREKKTKKRFAMKKIRKDNLLLRNQVEQIFAERDIMTFADSPFVVGLYCTFETRKYLCMIMEYVEGGDVATLIKSIGPLPDELARMYFAETVLALEYLHNFGIVHRDLKPDNLLITLEGHIKLTDFGLSKVGLMNLTTTLLESV-LNKDCTMFQDKQVFGTPDYIAPEVILRQGYDKMIDWWAMGIILYEFIVGCTPFYGDSTEELFGNIISGEIEWPQDPDPCVPDNAVNLITELLKRDPLVRLGA-EGTHEVKEHEFFSDVDWQGLLRQKALFIPVLDHEDDTSYFDPRTSRYQHESES 11226
+R +H QI++ D L + + IT +YF E++Q LE+ L E ++K PESL + +V+ LL I++RPARLLEC+EFDP EFY LLE AE +R D+P+YII KLGLD+DP +E +++S + + T + + QE+N + P E DF+ I+L+SNGAYGAV+LVR ++T++RFA+KK+ K L+LRNQV+Q+FAERDI+T AD+PFVV Y +FETR+YLCM+MEYVEGGD A L+KS G LP EL R+Y AET+LA+EYLH++GIVHRDLKPDNLLIT GHIKLTDFGLSK+GLMN TT + E + FQDKQ+ GTP+YIAPEVILR+GY K +DWWA+GIILYEF+VG PF+G++ E LF +IS ++E+P++ D +P A +L LL+++P RLG G ++ HEFF +D+ LLRQKA F+P LD+E+DTSYFD RT RY HE+ES
Sbjct: 206 TRFLHHQIVEIALDCLGKSKDDLITCSYFCEMSQRLEETLNEAQMKTSPESLEYLSKLVKKLLMIVSRPARLLECLEFDPDEFYHLLEEAEGVVREQLGSGTARVPDLPQYIIGKLGLDRDPLIDSTEHVDSSENTHATT-----------SGTTSAKGAGSAWQETNRA----------PCEDDFDTIRLVSNGAYGAVYLVRHRETRQRFALKKMNKQTLMLRNQVDQVFAERDILTMADNPFVVSFYGSFETRQYLCMLMEYVEGGDCAALLKSAGTLPVELVRLYVAETILAIEYLHSYGIVHRDLKPDNLLITAMGHIKLTDFGLSKIGLMNRTTLVAEGYDAVVETQQFQDKQLCGTPEYIAPEVILRRGYGKPVDWWALGIILYEFLVGIVPFFGETPEALFSKVISEDVEYPEE-DEALPPEAADLCRRLLEKNPAERLGTLNGAAQLMAHEFFILLDFTSLLRQKAEFVPQLDNEEDTSYFDTRTDRYNHEAES 686 HSP 2 Score: 77.7962 bits (190), Expect = 2.353e-13 Identity = 39/115 (33.91%), Postives = 65/115 (56.52%), Query Frame = 1
Query: 12130 IVIHRRSRNFGFVIRAIRVFYGE-SNVYTLHHLIVGVDPEGSAFQAGLREGDLITHINGVSIVGAYHTEVVSMIIQSGASISLRVIPINKSFIRTDGPWRPAGKMATKHHPRKAQ 12471
I I + FGF ++++RV+ GE S YT+ H++ V AF A L+ D+ITH+NG + H +++ ++ +G + LR++P+ + IR R GKMA K P++ Q
Sbjct: 987 ITIRKGPFGFGFTLKSVRVYLGEHSEYYTIEHIVTAVVEGSPAFHANLQAEDMITHVNGHPVHNLTHPQLMHRLLANGNELILRLVPLANTSIREGAARRTVGKMARK-KPKRPQ 1100
BLAST of Talin-1 vs. Ensembl Celegans
Match: kin-4 (KIN-4 protein; Protein KINase [Source:UniProtKB/TrEMBL;Acc:G5EFA4]) HSP 1 Score: 529.635 bits (1363), Expect = 8.709e-156 Identity = 263/503 (52.29%), Postives = 350/503 (69.58%), Query Frame = 1
Query: 9748 SRLVHTQIMKHVKDILNMTNLEAITSTYFFELTQNLEKLLKETRLKC-PESLARVRPIVQHLLFIIARPARLLECIEFDPKEFYKLLEVAENNLRNVQT-------DVPKYIISKLGLDKDPYDIGSEELNTSLELNGGSLEIXXXXXXXXXXXXXXXXXLNMSQESNNSLELSFSKSMTPKESDFEDIKLISNGAYGAVHLVREKKTKKRFAMKKIRKDNLLLRNQVEQIFAERDIMTFADSPFVVGLYCTFETRKYLCMIMEYVEGGDVATLIKSIGPLPDELARMYFAETVLALEYLHNFGIVHRDLKPDNLLITLEGHIKLTDFGLSKVGLMNLTTTLLESV-LNKDCTMFQDKQVFGTPDYIAPEVILRQGYDKMIDWWAMGIILYEFIVGCTPFYGDSTEELFGNIISGEIEWPQDPDPCVPDNAVNLITELLKRDPLVRLGA-EGTHEVKEHEFFSDVDWQGLLRQKALFIPVLDHEDDTSYFDPRTSRYQHESES 11226
+R +H QI++ D L + + IT +YF E++Q LE+ L E ++K PESL + +V+ LL I++RPARLLEC+EFDP EFY LLE AE +R D+P+YII KLGLD+DP +E +++S + + T + + QE+N + P E DF+ I+L+SNGAYGAV+LVR ++T++RFA+KK+ K L+LRNQV+Q+FAERDI+T AD+PFVV Y +FETR+YLCM+MEYVEGGD A L+KS G LP EL R+Y AET+LA+EYLH++GIVHRDLKPDNLLIT GHIKLTDFGLSK+GLMN TT + E + FQDKQ+ GTP+YIAPEVILR+GY K +DWWA+GIILYEF+VG PF+G++ E LF +IS ++E+P++ D +P A +L LL+++P RLG G ++ HEFF +D+ LLRQKA F+P LD+E+DTSYFD RT RY HE+ES
Sbjct: 389 TRFLHHQIVEIALDCLGKSKDDLITCSYFCEMSQRLEETLNEAQMKTSPESLEYLSKLVKKLLMIVSRPARLLECLEFDPDEFYHLLEEAEGVVREQLGSGTARVPDLPQYIIGKLGLDRDPLIDSTEHVDSSENTHATT-----------SGTTSAKGAGSAWQETNRA----------PCEDDFDTIRLVSNGAYGAVYLVRHRETRQRFALKKMNKQTLMLRNQVDQVFAERDILTMADNPFVVSFYGSFETRQYLCMLMEYVEGGDCAALLKSAGTLPVELVRLYVAETILAIEYLHSYGIVHRDLKPDNLLITAMGHIKLTDFGLSKIGLMNRTTLVAEGYDAVVETQQFQDKQLCGTPEYIAPEVILRRGYGKPVDWWALGIILYEFLVGIVPFFGETPEALFSKVISEDVEYPEE-DEALPPEAADLCRRLLEKNPAERLGTLNGAAQLMAHEFFILLDFTSLLRQKAEFVPQLDNEEDTSYFDTRTDRYNHEAES 869 HSP 2 Score: 77.7962 bits (190), Expect = 2.339e-13 Identity = 39/115 (33.91%), Postives = 65/115 (56.52%), Query Frame = 1
Query: 12130 IVIHRRSRNFGFVIRAIRVFYGE-SNVYTLHHLIVGVDPEGSAFQAGLREGDLITHINGVSIVGAYHTEVVSMIIQSGASISLRVIPINKSFIRTDGPWRPAGKMATKHHPRKAQ 12471
I I + FGF ++++RV+ GE S YT+ H++ V AF A L+ D+ITH+NG + H +++ ++ +G + LR++P+ + IR R GKMA K P++ Q
Sbjct: 1170 ITIRKGPFGFGFTLKSVRVYLGEHSEYYTIEHIVTAVVEGSPAFHANLQAEDMITHVNGHPVHNLTHPQLMHRLLANGNELILRLVPLANTSIREGAARRTVGKMARK-KPKRPQ 1283
BLAST of Talin-1 vs. Ensembl Celegans
Match: kin-4 (KIN-4 protein; Protein KINase [Source:UniProtKB/TrEMBL;Acc:G5EFA4]) HSP 1 Score: 530.02 bits (1364), Expect = 2.971e-155 Identity = 263/503 (52.29%), Postives = 350/503 (69.58%), Query Frame = 1
Query: 9748 SRLVHTQIMKHVKDILNMTNLEAITSTYFFELTQNLEKLLKETRLKC-PESLARVRPIVQHLLFIIARPARLLECIEFDPKEFYKLLEVAENNLRNVQT-------DVPKYIISKLGLDKDPYDIGSEELNTSLELNGGSLEIXXXXXXXXXXXXXXXXXLNMSQESNNSLELSFSKSMTPKESDFEDIKLISNGAYGAVHLVREKKTKKRFAMKKIRKDNLLLRNQVEQIFAERDIMTFADSPFVVGLYCTFETRKYLCMIMEYVEGGDVATLIKSIGPLPDELARMYFAETVLALEYLHNFGIVHRDLKPDNLLITLEGHIKLTDFGLSKVGLMNLTTTLLESV-LNKDCTMFQDKQVFGTPDYIAPEVILRQGYDKMIDWWAMGIILYEFIVGCTPFYGDSTEELFGNIISGEIEWPQDPDPCVPDNAVNLITELLKRDPLVRLGA-EGTHEVKEHEFFSDVDWQGLLRQKALFIPVLDHEDDTSYFDPRTSRYQHESES 11226
+R +H QI++ D L + + IT +YF E++Q LE+ L E ++K PESL + +V+ LL I++RPARLLEC+EFDP EFY LLE AE +R D+P+YII KLGLD+DP +E +++S + + T + + QE+N + P E DF+ I+L+SNGAYGAV+LVR ++T++RFA+KK+ K L+LRNQV+Q+FAERDI+T AD+PFVV Y +FETR+YLCM+MEYVEGGD A L+KS G LP EL R+Y AET+LA+EYLH++GIVHRDLKPDNLLIT GHIKLTDFGLSK+GLMN TT + E + FQDKQ+ GTP+YIAPEVILR+GY K +DWWA+GIILYEF+VG PF+G++ E LF +IS ++E+P++ D +P A +L LL+++P RLG G ++ HEFF +D+ LLRQKA F+P LD+E+DTSYFD RT RY HE+ES
Sbjct: 469 TRFLHHQIVEIALDCLGKSKDDLITCSYFCEMSQRLEETLNEAQMKTSPESLEYLSKLVKKLLMIVSRPARLLECLEFDPDEFYHLLEEAEGVVREQLGSGTARVPDLPQYIIGKLGLDRDPLIDSTEHVDSSENTHATT-----------SGTTSAKGAGSAWQETNRA----------PCEDDFDTIRLVSNGAYGAVYLVRHRETRQRFALKKMNKQTLMLRNQVDQVFAERDILTMADNPFVVSFYGSFETRQYLCMLMEYVEGGDCAALLKSAGTLPVELVRLYVAETILAIEYLHSYGIVHRDLKPDNLLITAMGHIKLTDFGLSKIGLMNRTTLVAEGYDAVVETQQFQDKQLCGTPEYIAPEVILRRGYGKPVDWWALGIILYEFLVGIVPFFGETPEALFSKVISEDVEYPEE-DEALPPEAADLCRRLLEKNPAERLGTLNGAAQLMAHEFFILLDFTSLLRQKAEFVPQLDNEEDTSYFDTRTDRYNHEAES 949 HSP 2 Score: 77.411 bits (189), Expect = 2.578e-13 Identity = 39/115 (33.91%), Postives = 65/115 (56.52%), Query Frame = 1
Query: 12130 IVIHRRSRNFGFVIRAIRVFYGE-SNVYTLHHLIVGVDPEGSAFQAGLREGDLITHINGVSIVGAYHTEVVSMIIQSGASISLRVIPINKSFIRTDGPWRPAGKMATKHHPRKAQ 12471
I I + FGF ++++RV+ GE S YT+ H++ V AF A L+ D+ITH+NG + H +++ ++ +G + LR++P+ + IR R GKMA K P++ Q
Sbjct: 1250 ITIRKGPFGFGFTLKSVRVYLGEHSEYYTIEHIVTAVVEGSPAFHANLQAEDMITHVNGHPVHNLTHPQLMHRLLANGNELILRLVPLANTSIREGAARRTVGKMARK-KPKRPQ 1363
BLAST of Talin-1 vs. Ensembl Fly
Match: rhea (gene:FBgn0260442 transcript:FBtr0305210) HSP 1 Score: 900.968 bits (2327), Expect = 0.000e+0 Identity = 685/2447 (27.99%), Postives = 1232/2447 (50.35%), Query Frame = 1
Query: 49 FELRIHIVDADVTKIVPLDPEATIFQLCETIRKNIREAQTKSPKSYGLYLPHDDLKKGLWLDNSKTLQHYILKRGDTIEYRNRSRWLHIRTMDGTNKTLKVDDSWTVSELMLTVCTKLGIYNYDEYSLI-----SDKMDFSPGIDKTLSMKRGISINXXXXXXXXXXXXYHTEDGLNWLNPSQSLRQQGIEESEVLLLKRKYFFSDMNVDSRDPIQLSLLYEQLKDAVINGTHPVTLPEAIELAGLQCQVQLGNYSADKFKPGFLDLRECLPKEYQKNPKTVEKKIFNQHSKSKDLSEVEAKEKYCLLCRSFKTYGITFFLVKEKVIGKNKLIPRLLGVNKESVVQVDEKTKEIINTWPLTSIRKWAASFNGFTMDFGEYSPDEYYTAQTDKGERISQLIAGYIDIILKRKKAKDHLGVDADEESIMYEENIAPSKAIIVEHVPKQKRSSVSEEDVVIRKKAHMANSSVRMNSQASDSVCSQDCTDFYQE-DINMSRQTSSLGRTQSPSSSLTTNSMHYRMSDDDIRQKLYIISLQDNLDTIQKYKDQLMIENKGPEIGKDEASQQWIYVNIDNSRQRMADEIGAMNAAVAQVLRSAQGLATIXXXXXXXXXXXXIAKMQNSFSLITVHLPSLMEEIRTAAYYQDQLTDEDVSGEELIAAAKRLADAFTNLIKAAYPVEDQKRSLNRKEIFDAANAVGEASSDLLQQITEQENCQIELKSERPYSIIMITEEDQLYQEELLRLAKSVANETTNLIKQVKVIAVEAENPSDQKKVVMAATETGLAISQLISTTKIVAPTIEQSVCQEQLIFSIEDVSKAIQVVVESSNKATQSEELQDLTVQAANQVQEALDTLMKHLRXXXXXXXXXXXXXXA-YENI---QEXXXXXXXXXXXXXXXRRLAQATTAMISEIQLKAVNEQYKTPEERDKLINAAKQLAEATTVLIDSAKNCTMDKDEMNLRYTLREATERFIVVTYTTECATYIQEQVIDHLLVAARKAATTGTHLINTSLSAAKKSRASNFK--VCNDGRELSNQISNLIVAIKEARRDPKDHLAQLELIAACRDYIDPSEQLSQSNKYMWPTVSDPSLQTALNQSINQSVIATEELKKCVHQADLMCQHLDLSAALEQLKRLEQNLKSIKNSIERENLIPLPDEKSDESAALLIKSVRRSGSAANQFKNDLESRCVVYEQTNGEDSYQNLENLDVAGQKARELSMALDRLVHAARGVAASIEFENQESENNDKNLEKLAQLQIVNNCLEAVKAARDLVIEAKSSPPDNDQMDRAQQASVRXXXXXXXXXXXXPGQRDLDMLSKHIESKKHQFAENRLPIQQNNNINLSNCRSELTDTTFDFNQAVNEL-VSAPSFNLVNKGCKKMRMSYDRIVEICNVLVHDPFDESDSALHHLSSNRDHIANGVMIMSEDCQTLLDKVKKIQCEPDNIIVRKQLQEATKMLLDSINRLLTNISTNLRPGQKECDKTIYRLESMRPILDNPVHPISHKDYFECLDFIIDKTVQPLADSLKNIPAAVKDENNQKFIDSIYHCADSVCMLLEETAQTAYLVGVGDVRSKIGNKGLADHTSFLQIQKEISENCQTICNPDTTARQDSSLMISTAGQIAENSRKLCEASK--TIMISFPNDKIKLSDKTKITLLAVSELMTGVQNLNQNFNEDNRKEVESLSGKVQDNVAELVQLLLSYKFAGDAAIISEEAKESQGPIKAAGITVLDTAIEVIQCSKALISSEANEELFIAYSSSCKDLNDALKHLISTIKESAPGQKECDEXXXXXXXXXXQAYDSKMKIMKHRSRTISRTFESE-ESYQNILQSALIQMPHCINELSRAGKKEPEQLARIFSRQTQLLESMVNSCICAANQTDLIQNSNIYLEHLITILEASEQLLKAVKKSGGNPKANSVHSQIDEMAQGVIESCEDLLAALDKISFKQGNVNTIVE----TITKSSAKVQESAIIPEKSRFGNSQSKMLDICYDMNNLTTDISSNANSESTQRLLAPLTQNLTQRYDDLCRACQGAVATLSNENNGKQLQECVQTVGKVSISLVKSTT-EVRPSVASSISNLQAKTQELHKRIDDVIQLLISSNVGTQACTQAIKILKEINSDIDTSILFVKSADIQNDDREYYSVKELFKKSRNSVIDNSSELVRNIKLIVSKDVCDVNILQESADQIAITSQSLANDVKVGLEHLNSSTSQYNIELLVSFQEVIVSLISFLEVARNTSGLPYTDPLFQNLKEEGKCSINAITSLLKVLKSMDDVNLKDFQAIDNAIIXXXXXXXXXXXXXXGISREASPVESPTSTNRLSIGSDITVSPRFAPEEINRLIPSLANVCDKILEISSPEFKP-IIRQENISVVSISCSKVNNELTSACKNLLRNGPVTDS-KKQTLNTVDQLVENYTELLKNFKLYLTNPTKETRIPVETVVSK-LNELIKLLR 7317
LRI + VTK + P T+F C+ IR EA P YGL++ + ++G+WL+ +TL +YIL DT+EYR ++R L +R +DG KT+ VDDS VS+LM+ +CTK+GI N++EY L+ + + TL++KR I K++ L+KK T+D +NW++ S++LR+QGI+E+E +LL+R++FFSD N+DSRDP+QL+LLY Q +DA+++GTHPVT +A E AG+Q +Q G ++ K K GFLDL++ LP+ Y + K +EKKIF++H K DLSE++AK Y R TYG+TFFLVKEK+ GKNKL+PRLLGV K+SV+++DE TKEI+ +WPLT++R+W AS N FT+DFG+Y+ ++YY+ QT + E+I QLIAGYIDIILK+K+ KDH G++ DE S M EE++APSKA ++H + E + + AH + D Y E ++ + + +G+ TT + + Q+ + + D + + ++L + E+G D S +W +D S+Q ++ + M+AA AQ++ ++ +E + S S I +P + +E+R A L + D SG++L+ AA+ L AF++L+KAA P + + + +AA+ VGEA++ +L I E+E E++ + LL LAK+VAN T L+ + K IA ++ + +V+ AA++ LA SQL++ K+VAPT+ + C+EQL + ++V++A+ + E N+A+ +L+ + AA V ++L +++H++ ++ + L+ EN+ ++ S D ++V AR L Q T +I I+ +A +Q + + + L++AAKQLA+AT L+++A+ C+ + + + + LR+A E +T T ++ +I L +++AA+ T I+ + +A + S+ K + D + +++ I L+ ++K R P D AQL LI A +I+P+ Q+S+S++ + PTV+D T L++ EL +A C +L +ALE++++L L + + L PLP + + +A L KS + G A +Q + V++ Q SY AG R+ ++AL + GVAA+ + I++ + V ++ L+ +A+ + + QA ++ ALS +D +PGQR++D+ +++ + + P L +SEL + A E+ VS S L+ + + +Y ++ + + +E R H+ + +S +LL K I +P + L A + + +SIN+L+ + S PGQKECD + +E++R +LD P PI+ YF+C++ K+ + L ++ + K + +F S+ + DS+ L+E ++Q AYL+GV S G G+ D + I ++C + + +T Q MIS IA+++ LC + ++ S P K + K A S+L+ ++ + + +R E L + + V + Q S +F+ A IS E +++Q P+ AG V+D +E+++ +K+L + N ++ S +++++K L+ I++ APGQ +C++ L L ++ + + ++ +S+ ++ + ++ ++ + + AGK EQL ++ + MVN I A Q ++ +++E++ L+++ K+S GNP+A H ++D+ G E+ ++L ++KI+ + G V ++E +IT+ + K Q F + Q++M+ ++ +L ++ NA S L L ++TQ Y L + GA T S+ + +++ V +G+ S+++S+ RP+ A + + +E+ +++ V+ L + + GTQAC A + I D+DT+I+F + + +D F R ++ + LV + K++V+ + L +A T LA VK G L S+ + ++ + ++V +L + + SG DP Q+LKE + + ++SLLK +K+++D + + +A++ + IS+E + SP +G PE++ R+ ++ K + + + I+ N+ +IS E+ C+++ N T+ + +TL + E+Y +LL L N + + R+ + V+K + +L+ + R
Sbjct: 4 LSLRIQLEGGRVTKTIQFQPNTTVFDACKVIRDKFAEAVQGQPSEYGLFISDEQNQQGVWLEPGRTLGYYILHNQDTLEYRRKTRTLRVRMLDGAVKTILVDDSQPVSQLMVVICTKIGITNHEEYGLVREDNEAQNENLPDNKFGTLTLKRKIMEKDRDAKMESLRKKLKTDDEMNWVDVSRTLREQGIDEAETVLLRRRFFFSDQNIDSRDPVQLNLLYVQARDAILDGTHPVTQDKACEFAGIQVHIQFGPHNEAKHKTGFLDLKDFLPQSYVRT-KGIEKKIFSEHRKHVDLSEIDAKVLYTKTARELPTYGVTFFLVKEKMNGKNKLVPRLLGVTKDSVLRLDEHTKEILISWPLTTVRRWGASPNTFTLDFGDYA-NQYYSVQTTEAEQIVQLIAGYIDIILKKKQTKDHFGIEGDEGSTMVEESVAPSKATFLQHETNRM------EQLNVESLAH------------PGIMRPYDGERSYMENEVQTVQYGAFVGQVNHAHQPPTTKEVRISSVNLTEPQRALLGYISAGQDVLIRADEELRTKAPIQELGSDLRSIEWRENTLDTSKQAVSSHVATMSAATAQIITASH------------PDEVDTEAISASVSQIAQTIPEVTKEVRLIAA----LMENDTSGDQLLEAARNLCSAFSDLLKAAEPESKEP----PQHLINAASRVGEATTHVLSTIAEEE-----------------VPENRDLHDMLLALAKAVANTTAALVLRAKNIAASCDDEQARNRVIGAASQCALATSQLVACAKVVAPTLHNAACREQLEAAAKNVARAVNSLCEVCNEASNDPKLKADLLAAARDVSKSLTDMLEHVKLSSREHANRTSTELSPVENVIIGTDILVSTHDPQEMVRHARTLGQTTAQLIQSIKGEA--DQQQDADMKRHLLSAAKQLADATAKLVEAARLCSSNPHDSDNQNALRKAAEELREITTTAANTPAMKRGLIQRLEFCSKQAASAATQCISAAQNAVQHSQDHQTKETLLQDCKRVADTIPRLVTSLKTTRAQPDDPNAQLNLIEAAEQFIEPALQVSKSSRALQPTVTDIPSATQLSKGALHLGQCVSELHSVAQRARDACGGQELESALEEVRKLHDVLDDTRQAAIAGQLRPLPGQTVENTADELRKSAKNVGIALSQLLS-----SVLHNQR----SY--------AGAAGRDTALALGDFTRSVHGVAATTQ-----------------NPAIIDCADDVVTSSARLIEQAQRTLQGASNPEALTQAGREVTGALSATVDCIPGQREVDVALRNVSELSEILSMSEFPPSSRPYATL---QSELKQVAEQLSSAGGEIVVSYSSPALLAESSQNFAANYRDLLSVSMEMAGQTQEE---------EVRSHMIESLRHVSTQSCSLLSTAKSIAADPGQPNAKNLLHAAARGVTESINQLV-DASIQSAPGQKECDNAMRNIEALRLMLDYPHEPINELGYFDCVEQATGKS-RNLGYAISEMINNAKQSQHVEFSQSVNNVNDSIQGLIESSSQAAYLIGVSHPSSVAGRPGIIDQAQLTWAYQGIRQHCDIVSSQQSTKPQ----MISALTVIAKHTSYLCSICRQASMNTSNPVAKNEFIVLAKQVATATSDLVQDIKAIEEQSAGGSR---ERLVDPLLEAVKAVRQYASSSEFSSVPAKISAEGRKAQEPVIQAGRGVIDGVVEMVKAAKSLALTPDNPPVWQQLSMHSTPVSESVKRLVDNIRDKAPGQAQCEQVLHTLGTCTRELDSCALAV---NAQGLSQRRDNNLHGFSGQTMNSASELIDKLEPIRMAGKNNAEQLGHAVGEISRYVVPMVNGAIGACTHIVHSQQQMSLIQQTRSVVESAITLVQSAKESAGNPRATHAHPRLDDAIDGTREAIQELQQTVEKINAETGIVTGLMEQVNRSITRLTDKRQSLLNASYSDTFVDYQTRMVARAKEIASLANEM--NAKSSVEPSALPQLAVDMTQNYQQLTQDSVGASTTTSSPDVAMRIRTTVIDLGRSVSSMIQSSAGGARPNDAGAQKEIARSAREVSEKVAQVLAALQAGSRGTQACINAAHTVSGIIGDLDTTIMFATAGTLHSDGDGS------FADHREHILQTAKALVEDTKVLVTGAAGTQDQLANAAQNAVSTITQLAEAVKRGACSLGSTQPDSQVMVINAVKDVASALGDLINCTKLASGKSINDPSMQDLKESARVMVLNVSSLLKTVKAVEDEHTRGTRAMEATV--------------EAISQEIRAMHSPPPVGNTQVG----------PEDLIRVTMNVTAATAKAVAAGTSNLQADIVSAANLGRRAIS------EMLIVCRSVAWNCAETEELRSRTLEAGTAVGESYRDLLSGI---LHNCSADDRMHLSRRVAKCVTDLVAMAR 2292
BLAST of Talin-1 vs. Ensembl Fly
Match: rhea (gene:FBgn0260442 transcript:FBtr0333105) HSP 1 Score: 900.968 bits (2327), Expect = 0.000e+0 Identity = 685/2447 (27.99%), Postives = 1232/2447 (50.35%), Query Frame = 1
Query: 49 FELRIHIVDADVTKIVPLDPEATIFQLCETIRKNIREAQTKSPKSYGLYLPHDDLKKGLWLDNSKTLQHYILKRGDTIEYRNRSRWLHIRTMDGTNKTLKVDDSWTVSELMLTVCTKLGIYNYDEYSLI-----SDKMDFSPGIDKTLSMKRGISINXXXXXXXXXXXXYHTEDGLNWLNPSQSLRQQGIEESEVLLLKRKYFFSDMNVDSRDPIQLSLLYEQLKDAVINGTHPVTLPEAIELAGLQCQVQLGNYSADKFKPGFLDLRECLPKEYQKNPKTVEKKIFNQHSKSKDLSEVEAKEKYCLLCRSFKTYGITFFLVKEKVIGKNKLIPRLLGVNKESVVQVDEKTKEIINTWPLTSIRKWAASFNGFTMDFGEYSPDEYYTAQTDKGERISQLIAGYIDIILKRKKAKDHLGVDADEESIMYEENIAPSKAIIVEHVPKQKRSSVSEEDVVIRKKAHMANSSVRMNSQASDSVCSQDCTDFYQE-DINMSRQTSSLGRTQSPSSSLTTNSMHYRMSDDDIRQKLYIISLQDNLDTIQKYKDQLMIENKGPEIGKDEASQQWIYVNIDNSRQRMADEIGAMNAAVAQVLRSAQGLATIXXXXXXXXXXXXIAKMQNSFSLITVHLPSLMEEIRTAAYYQDQLTDEDVSGEELIAAAKRLADAFTNLIKAAYPVEDQKRSLNRKEIFDAANAVGEASSDLLQQITEQENCQIELKSERPYSIIMITEEDQLYQEELLRLAKSVANETTNLIKQVKVIAVEAENPSDQKKVVMAATETGLAISQLISTTKIVAPTIEQSVCQEQLIFSIEDVSKAIQVVVESSNKATQSEELQDLTVQAANQVQEALDTLMKHLRXXXXXXXXXXXXXXA-YENI---QEXXXXXXXXXXXXXXXRRLAQATTAMISEIQLKAVNEQYKTPEERDKLINAAKQLAEATTVLIDSAKNCTMDKDEMNLRYTLREATERFIVVTYTTECATYIQEQVIDHLLVAARKAATTGTHLINTSLSAAKKSRASNFK--VCNDGRELSNQISNLIVAIKEARRDPKDHLAQLELIAACRDYIDPSEQLSQSNKYMWPTVSDPSLQTALNQSINQSVIATEELKKCVHQADLMCQHLDLSAALEQLKRLEQNLKSIKNSIERENLIPLPDEKSDESAALLIKSVRRSGSAANQFKNDLESRCVVYEQTNGEDSYQNLENLDVAGQKARELSMALDRLVHAARGVAASIEFENQESENNDKNLEKLAQLQIVNNCLEAVKAARDLVIEAKSSPPDNDQMDRAQQASVRXXXXXXXXXXXXPGQRDLDMLSKHIESKKHQFAENRLPIQQNNNINLSNCRSELTDTTFDFNQAVNEL-VSAPSFNLVNKGCKKMRMSYDRIVEICNVLVHDPFDESDSALHHLSSNRDHIANGVMIMSEDCQTLLDKVKKIQCEPDNIIVRKQLQEATKMLLDSINRLLTNISTNLRPGQKECDKTIYRLESMRPILDNPVHPISHKDYFECLDFIIDKTVQPLADSLKNIPAAVKDENNQKFIDSIYHCADSVCMLLEETAQTAYLVGVGDVRSKIGNKGLADHTSFLQIQKEISENCQTICNPDTTARQDSSLMISTAGQIAENSRKLCEASK--TIMISFPNDKIKLSDKTKITLLAVSELMTGVQNLNQNFNEDNRKEVESLSGKVQDNVAELVQLLLSYKFAGDAAIISEEAKESQGPIKAAGITVLDTAIEVIQCSKALISSEANEELFIAYSSSCKDLNDALKHLISTIKESAPGQKECDEXXXXXXXXXXQAYDSKMKIMKHRSRTISRTFESE-ESYQNILQSALIQMPHCINELSRAGKKEPEQLARIFSRQTQLLESMVNSCICAANQTDLIQNSNIYLEHLITILEASEQLLKAVKKSGGNPKANSVHSQIDEMAQGVIESCEDLLAALDKISFKQGNVNTIVE----TITKSSAKVQESAIIPEKSRFGNSQSKMLDICYDMNNLTTDISSNANSESTQRLLAPLTQNLTQRYDDLCRACQGAVATLSNENNGKQLQECVQTVGKVSISLVKSTT-EVRPSVASSISNLQAKTQELHKRIDDVIQLLISSNVGTQACTQAIKILKEINSDIDTSILFVKSADIQNDDREYYSVKELFKKSRNSVIDNSSELVRNIKLIVSKDVCDVNILQESADQIAITSQSLANDVKVGLEHLNSSTSQYNIELLVSFQEVIVSLISFLEVARNTSGLPYTDPLFQNLKEEGKCSINAITSLLKVLKSMDDVNLKDFQAIDNAIIXXXXXXXXXXXXXXGISREASPVESPTSTNRLSIGSDITVSPRFAPEEINRLIPSLANVCDKILEISSPEFKP-IIRQENISVVSISCSKVNNELTSACKNLLRNGPVTDS-KKQTLNTVDQLVENYTELLKNFKLYLTNPTKETRIPVETVVSK-LNELIKLLR 7317
LRI + VTK + P T+F C+ IR EA P YGL++ + ++G+WL+ +TL +YIL DT+EYR ++R L +R +DG KT+ VDDS VS+LM+ +CTK+GI N++EY L+ + + TL++KR I K++ L+KK T+D +NW++ S++LR+QGI+E+E +LL+R++FFSD N+DSRDP+QL+LLY Q +DA+++GTHPVT +A E AG+Q +Q G ++ K K GFLDL++ LP+ Y + K +EKKIF++H K DLSE++AK Y R TYG+TFFLVKEK+ GKNKL+PRLLGV K+SV+++DE TKEI+ +WPLT++R+W AS N FT+DFG+Y+ ++YY+ QT + E+I QLIAGYIDIILK+K+ KDH G++ DE S M EE++APSKA ++H + E + + AH + D Y E ++ + + +G+ TT + + Q+ + + D + + ++L + E+G D S +W +D S+Q ++ + M+AA AQ++ ++ +E + S S I +P + +E+R A L + D SG++L+ AA+ L AF++L+KAA P + + + +AA+ VGEA++ +L I E+E E++ + LL LAK+VAN T L+ + K IA ++ + +V+ AA++ LA SQL++ K+VAPT+ + C+EQL + ++V++A+ + E N+A+ +L+ + AA V ++L +++H++ ++ + L+ EN+ ++ S D ++V AR L Q T +I I+ +A +Q + + + L++AAKQLA+AT L+++A+ C+ + + + + LR+A E +T T ++ +I L +++AA+ T I+ + +A + S+ K + D + +++ I L+ ++K R P D AQL LI A +I+P+ Q+S+S++ + PTV+D T L++ EL +A C +L +ALE++++L L + + L PLP + + +A L KS + G A +Q + V++ Q SY AG R+ ++AL + GVAA+ + I++ + V ++ L+ +A+ + + QA ++ ALS +D +PGQR++D+ +++ + + P L +SEL + A E+ VS S L+ + + +Y ++ + + +E R H+ + +S +LL K I +P + L A + + +SIN+L+ + S PGQKECD + +E++R +LD P PI+ YF+C++ K+ + L ++ + K + +F S+ + DS+ L+E ++Q AYL+GV S G G+ D + I ++C + + +T Q MIS IA+++ LC + ++ S P K + K A S+L+ ++ + + +R E L + + V + Q S +F+ A IS E +++Q P+ AG V+D +E+++ +K+L + N ++ S +++++K L+ I++ APGQ +C++ L L ++ + + ++ +S+ ++ + ++ ++ + + AGK EQL ++ + MVN I A Q ++ +++E++ L+++ K+S GNP+A H ++D+ G E+ ++L ++KI+ + G V ++E +IT+ + K Q F + Q++M+ ++ +L ++ NA S L L ++TQ Y L + GA T S+ + +++ V +G+ S+++S+ RP+ A + + +E+ +++ V+ L + + GTQAC A + I D+DT+I+F + + +D F R ++ + LV + K++V+ + L +A T LA VK G L S+ + ++ + ++V +L + + SG DP Q+LKE + + ++SLLK +K+++D + + +A++ + IS+E + SP +G PE++ R+ ++ K + + + I+ N+ +IS E+ C+++ N T+ + +TL + E+Y +LL L N + + R+ + V+K + +L+ + R
Sbjct: 4 LSLRIQLEGGRVTKTIQFQPNTTVFDACKVIRDKFAEAVQGQPSEYGLFISDEQNQQGVWLEPGRTLGYYILHNQDTLEYRRKTRTLRVRMLDGAVKTILVDDSQPVSQLMVVICTKIGITNHEEYGLVREDNEAQNENLPDNKFGTLTLKRKIMEKDRDAKMESLRKKLKTDDEMNWVDVSRTLREQGIDEAETVLLRRRFFFSDQNIDSRDPVQLNLLYVQARDAILDGTHPVTQDKACEFAGIQVHIQFGPHNEAKHKTGFLDLKDFLPQSYVRT-KGIEKKIFSEHRKHVDLSEIDAKVLYTKTARELPTYGVTFFLVKEKMNGKNKLVPRLLGVTKDSVLRLDEHTKEILISWPLTTVRRWGASPNTFTLDFGDYA-NQYYSVQTTEAEQIVQLIAGYIDIILKKKQTKDHFGIEGDEGSTMVEESVAPSKATFLQHETNRM------EQLNVESLAH------------PGIMRPYDGERSYMENEVQTVQYGAFVGQVNHAHQPPTTKEVRISSVNLTEPQRALLGYISAGQDVLIRADEELRTKAPIQELGSDLRSIEWRENTLDTSKQAVSSHVATMSAATAQIITASH------------PDEVDTEAISASVSQIAQTIPEVTKEVRLIAA----LMENDTSGDQLLEAARNLCSAFSDLLKAAEPESKEP----PQHLINAASRVGEATTHVLSTIAEEE-----------------VPENRDLHDMLLALAKAVANTTAALVLRAKNIAASCDDEQARNRVIGAASQCALATSQLVACAKVVAPTLHNAACREQLEAAAKNVARAVNSLCEVCNEASNDPKLKADLLAAARDVSKSLTDMLEHVKLSSREHANRTSTELSPVENVIIGTDILVSTHDPQEMVRHARTLGQTTAQLIQSIKGEA--DQQQDADMKRHLLSAAKQLADATAKLVEAARLCSSNPHDSDNQNALRKAAEELREITTTAANTPAMKRGLIQRLEFCSKQAASAATQCISAAQNAVQHSQDHQTKETLLQDCKRVADTIPRLVTSLKTTRAQPDDPNAQLNLIEAAEQFIEPALQVSKSSRALQPTVTDIPSATQLSKGALHLGQCVSELHSVAQRARDACGGQELESALEEVRKLHDVLDDTRQAAIAGQLRPLPGQTVENTADELRKSAKNVGIALSQLLS-----SVLHNQR----SY--------AGAAGRDTALALGDFTRSVHGVAATTQ-----------------NPAIIDCADDVVTSSARLIEQAQRTLQGASNPEALTQAGREVTGALSATVDCIPGQREVDVALRNVSELSEILSMSEFPPSSRPYATL---QSELKQVAEQLSSAGGEIVVSYSSPALLAESSQNFAANYRDLLSVSMEMAGQTQEE---------EVRSHMIESLRHVSTQSCSLLSTAKSIAADPGQPNAKNLLHAAARGVTESINQLV-DASIQSAPGQKECDNAMRNIEALRLMLDYPHEPINELGYFDCVEQATGKS-RNLGYAISEMINNAKQSQHVEFSQSVNNVNDSIQGLIESSSQAAYLIGVSHPSSVAGRPGIIDQAQLTWAYQGIRQHCDIVSSQQSTKPQ----MISALTVIAKHTSYLCSICRQASMNTSNPVAKNEFIVLAKQVATATSDLVQDIKAIEEQSAGGSR---ERLVDPLLEAVKAVRQYASSSEFSSVPAKISAEGRKAQEPVIQAGRGVIDGVVEMVKAAKSLALTPDNPPVWQQLSMHSTPVSESVKRLVDNIRDKAPGQAQCEQVLHTLGTCTRELDSCALAV---NAQGLSQRRDNNLHGFSGQTMNSASELIDKLEPIRMAGKNNAEQLGHAVGEISRYVVPMVNGAIGACTHIVHSQQQMSLIQQTRSVVESAITLVQSAKESAGNPRATHAHPRLDDAIDGTREAIQELQQTVEKINAETGIVTGLMEQVNRSITRLTDKRQSLLNASYSDTFVDYQTRMVARAKEIASLANEM--NAKSSVEPSALPQLAVDMTQNYQQLTQDSVGASTTTSSPDVAMRIRTTVIDLGRSVSSMIQSSAGGARPNDAGAQKEIARSAREVSEKVAQVLAALQAGSRGTQACINAAHTVSGIIGDLDTTIMFATAGTLHSDGDGS------FADHREHILQTAKALVEDTKVLVTGAAGTQDQLANAAQNAVSTITQLAEAVKRGACSLGSTQPDSQVMVINAVKDVASALGDLINCTKLASGKSINDPSMQDLKESARVMVLNVSSLLKTVKAVEDEHTRGTRAMEATV--------------EAISQEIRAMHSPPPVGNTQVG----------PEDLIRVTMNVTAATAKAVAAGTSNLQADIVSAANLGRRAIS------EMLIVCRSVAWNCAETEELRSRTLEAGTAVGESYRDLLSGI---LHNCSADDRMHLSRRVAKCVTDLVAMAR 2292
BLAST of Talin-1 vs. Ensembl Fly
Match: rhea (gene:FBgn0260442 transcript:FBtr0333106) HSP 1 Score: 900.968 bits (2327), Expect = 0.000e+0 Identity = 685/2447 (27.99%), Postives = 1232/2447 (50.35%), Query Frame = 1
Query: 49 FELRIHIVDADVTKIVPLDPEATIFQLCETIRKNIREAQTKSPKSYGLYLPHDDLKKGLWLDNSKTLQHYILKRGDTIEYRNRSRWLHIRTMDGTNKTLKVDDSWTVSELMLTVCTKLGIYNYDEYSLI-----SDKMDFSPGIDKTLSMKRGISINXXXXXXXXXXXXYHTEDGLNWLNPSQSLRQQGIEESEVLLLKRKYFFSDMNVDSRDPIQLSLLYEQLKDAVINGTHPVTLPEAIELAGLQCQVQLGNYSADKFKPGFLDLRECLPKEYQKNPKTVEKKIFNQHSKSKDLSEVEAKEKYCLLCRSFKTYGITFFLVKEKVIGKNKLIPRLLGVNKESVVQVDEKTKEIINTWPLTSIRKWAASFNGFTMDFGEYSPDEYYTAQTDKGERISQLIAGYIDIILKRKKAKDHLGVDADEESIMYEENIAPSKAIIVEHVPKQKRSSVSEEDVVIRKKAHMANSSVRMNSQASDSVCSQDCTDFYQE-DINMSRQTSSLGRTQSPSSSLTTNSMHYRMSDDDIRQKLYIISLQDNLDTIQKYKDQLMIENKGPEIGKDEASQQWIYVNIDNSRQRMADEIGAMNAAVAQVLRSAQGLATIXXXXXXXXXXXXIAKMQNSFSLITVHLPSLMEEIRTAAYYQDQLTDEDVSGEELIAAAKRLADAFTNLIKAAYPVEDQKRSLNRKEIFDAANAVGEASSDLLQQITEQENCQIELKSERPYSIIMITEEDQLYQEELLRLAKSVANETTNLIKQVKVIAVEAENPSDQKKVVMAATETGLAISQLISTTKIVAPTIEQSVCQEQLIFSIEDVSKAIQVVVESSNKATQSEELQDLTVQAANQVQEALDTLMKHLRXXXXXXXXXXXXXXA-YENI---QEXXXXXXXXXXXXXXXRRLAQATTAMISEIQLKAVNEQYKTPEERDKLINAAKQLAEATTVLIDSAKNCTMDKDEMNLRYTLREATERFIVVTYTTECATYIQEQVIDHLLVAARKAATTGTHLINTSLSAAKKSRASNFK--VCNDGRELSNQISNLIVAIKEARRDPKDHLAQLELIAACRDYIDPSEQLSQSNKYMWPTVSDPSLQTALNQSINQSVIATEELKKCVHQADLMCQHLDLSAALEQLKRLEQNLKSIKNSIERENLIPLPDEKSDESAALLIKSVRRSGSAANQFKNDLESRCVVYEQTNGEDSYQNLENLDVAGQKARELSMALDRLVHAARGVAASIEFENQESENNDKNLEKLAQLQIVNNCLEAVKAARDLVIEAKSSPPDNDQMDRAQQASVRXXXXXXXXXXXXPGQRDLDMLSKHIESKKHQFAENRLPIQQNNNINLSNCRSELTDTTFDFNQAVNEL-VSAPSFNLVNKGCKKMRMSYDRIVEICNVLVHDPFDESDSALHHLSSNRDHIANGVMIMSEDCQTLLDKVKKIQCEPDNIIVRKQLQEATKMLLDSINRLLTNISTNLRPGQKECDKTIYRLESMRPILDNPVHPISHKDYFECLDFIIDKTVQPLADSLKNIPAAVKDENNQKFIDSIYHCADSVCMLLEETAQTAYLVGVGDVRSKIGNKGLADHTSFLQIQKEISENCQTICNPDTTARQDSSLMISTAGQIAENSRKLCEASK--TIMISFPNDKIKLSDKTKITLLAVSELMTGVQNLNQNFNEDNRKEVESLSGKVQDNVAELVQLLLSYKFAGDAAIISEEAKESQGPIKAAGITVLDTAIEVIQCSKALISSEANEELFIAYSSSCKDLNDALKHLISTIKESAPGQKECDEXXXXXXXXXXQAYDSKMKIMKHRSRTISRTFESE-ESYQNILQSALIQMPHCINELSRAGKKEPEQLARIFSRQTQLLESMVNSCICAANQTDLIQNSNIYLEHLITILEASEQLLKAVKKSGGNPKANSVHSQIDEMAQGVIESCEDLLAALDKISFKQGNVNTIVE----TITKSSAKVQESAIIPEKSRFGNSQSKMLDICYDMNNLTTDISSNANSESTQRLLAPLTQNLTQRYDDLCRACQGAVATLSNENNGKQLQECVQTVGKVSISLVKSTT-EVRPSVASSISNLQAKTQELHKRIDDVIQLLISSNVGTQACTQAIKILKEINSDIDTSILFVKSADIQNDDREYYSVKELFKKSRNSVIDNSSELVRNIKLIVSKDVCDVNILQESADQIAITSQSLANDVKVGLEHLNSSTSQYNIELLVSFQEVIVSLISFLEVARNTSGLPYTDPLFQNLKEEGKCSINAITSLLKVLKSMDDVNLKDFQAIDNAIIXXXXXXXXXXXXXXGISREASPVESPTSTNRLSIGSDITVSPRFAPEEINRLIPSLANVCDKILEISSPEFKP-IIRQENISVVSISCSKVNNELTSACKNLLRNGPVTDS-KKQTLNTVDQLVENYTELLKNFKLYLTNPTKETRIPVETVVSK-LNELIKLLR 7317
LRI + VTK + P T+F C+ IR EA P YGL++ + ++G+WL+ +TL +YIL DT+EYR ++R L +R +DG KT+ VDDS VS+LM+ +CTK+GI N++EY L+ + + TL++KR I K++ L+KK T+D +NW++ S++LR+QGI+E+E +LL+R++FFSD N+DSRDP+QL+LLY Q +DA+++GTHPVT +A E AG+Q +Q G ++ K K GFLDL++ LP+ Y + K +EKKIF++H K DLSE++AK Y R TYG+TFFLVKEK+ GKNKL+PRLLGV K+SV+++DE TKEI+ +WPLT++R+W AS N FT+DFG+Y+ ++YY+ QT + E+I QLIAGYIDIILK+K+ KDH G++ DE S M EE++APSKA ++H + E + + AH + D Y E ++ + + +G+ TT + + Q+ + + D + + ++L + E+G D S +W +D S+Q ++ + M+AA AQ++ ++ +E + S S I +P + +E+R A L + D SG++L+ AA+ L AF++L+KAA P + + + +AA+ VGEA++ +L I E+E E++ + LL LAK+VAN T L+ + K IA ++ + +V+ AA++ LA SQL++ K+VAPT+ + C+EQL + ++V++A+ + E N+A+ +L+ + AA V ++L +++H++ ++ + L+ EN+ ++ S D ++V AR L Q T +I I+ +A +Q + + + L++AAKQLA+AT L+++A+ C+ + + + + LR+A E +T T ++ +I L +++AA+ T I+ + +A + S+ K + D + +++ I L+ ++K R P D AQL LI A +I+P+ Q+S+S++ + PTV+D T L++ EL +A C +L +ALE++++L L + + L PLP + + +A L KS + G A +Q + V++ Q SY AG R+ ++AL + GVAA+ + I++ + V ++ L+ +A+ + + QA ++ ALS +D +PGQR++D+ +++ + + P L +SEL + A E+ VS S L+ + + +Y ++ + + +E R H+ + +S +LL K I +P + L A + + +SIN+L+ + S PGQKECD + +E++R +LD P PI+ YF+C++ K+ + L ++ + K + +F S+ + DS+ L+E ++Q AYL+GV S G G+ D + I ++C + + +T Q MIS IA+++ LC + ++ S P K + K A S+L+ ++ + + +R E L + + V + Q S +F+ A IS E +++Q P+ AG V+D +E+++ +K+L + N ++ S +++++K L+ I++ APGQ +C++ L L ++ + + ++ +S+ ++ + ++ ++ + + AGK EQL ++ + MVN I A Q ++ +++E++ L+++ K+S GNP+A H ++D+ G E+ ++L ++KI+ + G V ++E +IT+ + K Q F + Q++M+ ++ +L ++ NA S L L ++TQ Y L + GA T S+ + +++ V +G+ S+++S+ RP+ A + + +E+ +++ V+ L + + GTQAC A + I D+DT+I+F + + +D F R ++ + LV + K++V+ + L +A T LA VK G L S+ + ++ + ++V +L + + SG DP Q+LKE + + ++SLLK +K+++D + + +A++ + IS+E + SP +G PE++ R+ ++ K + + + I+ N+ +IS E+ C+++ N T+ + +TL + E+Y +LL L N + + R+ + V+K + +L+ + R
Sbjct: 4 LSLRIQLEGGRVTKTIQFQPNTTVFDACKVIRDKFAEAVQGQPSEYGLFISDEQNQQGVWLEPGRTLGYYILHNQDTLEYRRKTRTLRVRMLDGAVKTILVDDSQPVSQLMVVICTKIGITNHEEYGLVREDNEAQNENLPDNKFGTLTLKRKIMEKDRDAKMESLRKKLKTDDEMNWVDVSRTLREQGIDEAETVLLRRRFFFSDQNIDSRDPVQLNLLYVQARDAILDGTHPVTQDKACEFAGIQVHIQFGPHNEAKHKTGFLDLKDFLPQSYVRT-KGIEKKIFSEHRKHVDLSEIDAKVLYTKTARELPTYGVTFFLVKEKMNGKNKLVPRLLGVTKDSVLRLDEHTKEILISWPLTTVRRWGASPNTFTLDFGDYA-NQYYSVQTTEAEQIVQLIAGYIDIILKKKQTKDHFGIEGDEGSTMVEESVAPSKATFLQHETNRM------EQLNVESLAH------------PGIMRPYDGERSYMENEVQTVQYGAFVGQVNHAHQPPTTKEVRISSVNLTEPQRALLGYISAGQDVLIRADEELRTKAPIQELGSDLRSIEWRENTLDTSKQAVSSHVATMSAATAQIITASH------------PDEVDTEAISASVSQIAQTIPEVTKEVRLIAA----LMENDTSGDQLLEAARNLCSAFSDLLKAAEPESKEP----PQHLINAASRVGEATTHVLSTIAEEE-----------------VPENRDLHDMLLALAKAVANTTAALVLRAKNIAASCDDEQARNRVIGAASQCALATSQLVACAKVVAPTLHNAACREQLEAAAKNVARAVNSLCEVCNEASNDPKLKADLLAAARDVSKSLTDMLEHVKLSSREHANRTSTELSPVENVIIGTDILVSTHDPQEMVRHARTLGQTTAQLIQSIKGEA--DQQQDADMKRHLLSAAKQLADATAKLVEAARLCSSNPHDSDNQNALRKAAEELREITTTAANTPAMKRGLIQRLEFCSKQAASAATQCISAAQNAVQHSQDHQTKETLLQDCKRVADTIPRLVTSLKTTRAQPDDPNAQLNLIEAAEQFIEPALQVSKSSRALQPTVTDIPSATQLSKGALHLGQCVSELHSVAQRARDACGGQELESALEEVRKLHDVLDDTRQAAIAGQLRPLPGQTVENTADELRKSAKNVGIALSQLLS-----SVLHNQR----SY--------AGAAGRDTALALGDFTRSVHGVAATTQ-----------------NPAIIDCADDVVTSSARLIEQAQRTLQGASNPEALTQAGREVTGALSATVDCIPGQREVDVALRNVSELSEILSMSEFPPSSRPYATL---QSELKQVAEQLSSAGGEIVVSYSSPALLAESSQNFAANYRDLLSVSMEMAGQTQEE---------EVRSHMIESLRHVSTQSCSLLSTAKSIAADPGQPNAKNLLHAAARGVTESINQLV-DASIQSAPGQKECDNAMRNIEALRLMLDYPHEPINELGYFDCVEQATGKS-RNLGYAISEMINNAKQSQHVEFSQSVNNVNDSIQGLIESSSQAAYLIGVSHPSSVAGRPGIIDQAQLTWAYQGIRQHCDIVSSQQSTKPQ----MISALTVIAKHTSYLCSICRQASMNTSNPVAKNEFIVLAKQVATATSDLVQDIKAIEEQSAGGSR---ERLVDPLLEAVKAVRQYASSSEFSSVPAKISAEGRKAQEPVIQAGRGVIDGVVEMVKAAKSLALTPDNPPVWQQLSMHSTPVSESVKRLVDNIRDKAPGQAQCEQVLHTLGTCTRELDSCALAV---NAQGLSQRRDNNLHGFSGQTMNSASELIDKLEPIRMAGKNNAEQLGHAVGEISRYVVPMVNGAIGACTHIVHSQQQMSLIQQTRSVVESAITLVQSAKESAGNPRATHAHPRLDDAIDGTREAIQELQQTVEKINAETGIVTGLMEQVNRSITRLTDKRQSLLNASYSDTFVDYQTRMVARAKEIASLANEM--NAKSSVEPSALPQLAVDMTQNYQQLTQDSVGASTTTSSPDVAMRIRTTVIDLGRSVSSMIQSSAGGARPNDAGAQKEIARSAREVSEKVAQVLAALQAGSRGTQACINAAHTVSGIIGDLDTTIMFATAGTLHSDGDGS------FADHREHILQTAKALVEDTKVLVTGAAGTQDQLANAAQNAVSTITQLAEAVKRGACSLGSTQPDSQVMVINAVKDVASALGDLINCTKLASGKSINDPSMQDLKESARVMVLNVSSLLKTVKAVEDEHTRGTRAMEATV--------------EAISQEIRAMHSPPPVGNTQVG----------PEDLIRVTMNVTAATAKAVAAGTSNLQADIVSAANLGRRAIS------EMLIVCRSVAWNCAETEELRSRTLEAGTAVGESYRDLLSGI---LHNCSADDRMHLSRRVAKCVTDLVAMAR 2292
BLAST of Talin-1 vs. Ensembl Fly
Match: rhea (gene:FBgn0260442 transcript:FBtr0333108) HSP 1 Score: 900.582 bits (2326), Expect = 0.000e+0 Identity = 685/2447 (27.99%), Postives = 1232/2447 (50.35%), Query Frame = 1
Query: 49 FELRIHIVDADVTKIVPLDPEATIFQLCETIRKNIREAQTKSPKSYGLYLPHDDLKKGLWLDNSKTLQHYILKRGDTIEYRNRSRWLHIRTMDGTNKTLKVDDSWTVSELMLTVCTKLGIYNYDEYSLI-----SDKMDFSPGIDKTLSMKRGISINXXXXXXXXXXXXYHTEDGLNWLNPSQSLRQQGIEESEVLLLKRKYFFSDMNVDSRDPIQLSLLYEQLKDAVINGTHPVTLPEAIELAGLQCQVQLGNYSADKFKPGFLDLRECLPKEYQKNPKTVEKKIFNQHSKSKDLSEVEAKEKYCLLCRSFKTYGITFFLVKEKVIGKNKLIPRLLGVNKESVVQVDEKTKEIINTWPLTSIRKWAASFNGFTMDFGEYSPDEYYTAQTDKGERISQLIAGYIDIILKRKKAKDHLGVDADEESIMYEENIAPSKAIIVEHVPKQKRSSVSEEDVVIRKKAHMANSSVRMNSQASDSVCSQDCTDFYQE-DINMSRQTSSLGRTQSPSSSLTTNSMHYRMSDDDIRQKLYIISLQDNLDTIQKYKDQLMIENKGPEIGKDEASQQWIYVNIDNSRQRMADEIGAMNAAVAQVLRSAQGLATIXXXXXXXXXXXXIAKMQNSFSLITVHLPSLMEEIRTAAYYQDQLTDEDVSGEELIAAAKRLADAFTNLIKAAYPVEDQKRSLNRKEIFDAANAVGEASSDLLQQITEQENCQIELKSERPYSIIMITEEDQLYQEELLRLAKSVANETTNLIKQVKVIAVEAENPSDQKKVVMAATETGLAISQLISTTKIVAPTIEQSVCQEQLIFSIEDVSKAIQVVVESSNKATQSEELQDLTVQAANQVQEALDTLMKHLRXXXXXXXXXXXXXXA-YENI---QEXXXXXXXXXXXXXXXRRLAQATTAMISEIQLKAVNEQYKTPEERDKLINAAKQLAEATTVLIDSAKNCTMDKDEMNLRYTLREATERFIVVTYTTECATYIQEQVIDHLLVAARKAATTGTHLINTSLSAAKKSRASNFK--VCNDGRELSNQISNLIVAIKEARRDPKDHLAQLELIAACRDYIDPSEQLSQSNKYMWPTVSDPSLQTALNQSINQSVIATEELKKCVHQADLMCQHLDLSAALEQLKRLEQNLKSIKNSIERENLIPLPDEKSDESAALLIKSVRRSGSAANQFKNDLESRCVVYEQTNGEDSYQNLENLDVAGQKARELSMALDRLVHAARGVAASIEFENQESENNDKNLEKLAQLQIVNNCLEAVKAARDLVIEAKSSPPDNDQMDRAQQASVRXXXXXXXXXXXXPGQRDLDMLSKHIESKKHQFAENRLPIQQNNNINLSNCRSELTDTTFDFNQAVNEL-VSAPSFNLVNKGCKKMRMSYDRIVEICNVLVHDPFDESDSALHHLSSNRDHIANGVMIMSEDCQTLLDKVKKIQCEPDNIIVRKQLQEATKMLLDSINRLLTNISTNLRPGQKECDKTIYRLESMRPILDNPVHPISHKDYFECLDFIIDKTVQPLADSLKNIPAAVKDENNQKFIDSIYHCADSVCMLLEETAQTAYLVGVGDVRSKIGNKGLADHTSFLQIQKEISENCQTICNPDTTARQDSSLMISTAGQIAENSRKLCEASK--TIMISFPNDKIKLSDKTKITLLAVSELMTGVQNLNQNFNEDNRKEVESLSGKVQDNVAELVQLLLSYKFAGDAAIISEEAKESQGPIKAAGITVLDTAIEVIQCSKALISSEANEELFIAYSSSCKDLNDALKHLISTIKESAPGQKECDEXXXXXXXXXXQAYDSKMKIMKHRSRTISRTFESE-ESYQNILQSALIQMPHCINELSRAGKKEPEQLARIFSRQTQLLESMVNSCICAANQTDLIQNSNIYLEHLITILEASEQLLKAVKKSGGNPKANSVHSQIDEMAQGVIESCEDLLAALDKISFKQGNVNTIVE----TITKSSAKVQESAIIPEKSRFGNSQSKMLDICYDMNNLTTDISSNANSESTQRLLAPLTQNLTQRYDDLCRACQGAVATLSNENNGKQLQECVQTVGKVSISLVKSTT-EVRPSVASSISNLQAKTQELHKRIDDVIQLLISSNVGTQACTQAIKILKEINSDIDTSILFVKSADIQNDDREYYSVKELFKKSRNSVIDNSSELVRNIKLIVSKDVCDVNILQESADQIAITSQSLANDVKVGLEHLNSSTSQYNIELLVSFQEVIVSLISFLEVARNTSGLPYTDPLFQNLKEEGKCSINAITSLLKVLKSMDDVNLKDFQAIDNAIIXXXXXXXXXXXXXXGISREASPVESPTSTNRLSIGSDITVSPRFAPEEINRLIPSLANVCDKILEISSPEFKP-IIRQENISVVSISCSKVNNELTSACKNLLRNGPVTDS-KKQTLNTVDQLVENYTELLKNFKLYLTNPTKETRIPVETVVSK-LNELIKLLR 7317
LRI + VTK + P T+F C+ IR EA P YGL++ + ++G+WL+ +TL +YIL DT+EYR ++R L +R +DG KT+ VDDS VS+LM+ +CTK+GI N++EY L+ + + TL++KR I K++ L+KK T+D +NW++ S++LR+QGI+E+E +LL+R++FFSD N+DSRDP+QL+LLY Q +DA+++GTHPVT +A E AG+Q +Q G ++ K K GFLDL++ LP+ Y + K +EKKIF++H K DLSE++AK Y R TYG+TFFLVKEK+ GKNKL+PRLLGV K+SV+++DE TKEI+ +WPLT++R+W AS N FT+DFG+Y+ ++YY+ QT + E+I QLIAGYIDIILK+K+ KDH G++ DE S M EE++APSKA ++H + E + + AH + D Y E ++ + + +G+ TT + + Q+ + + D + + ++L + E+G D S +W +D S+Q ++ + M+AA AQ++ ++ +E + S S I +P + +E+R A L + D SG++L+ AA+ L AF++L+KAA P + + + +AA+ VGEA++ +L I E+E E++ + LL LAK+VAN T L+ + K IA ++ + +V+ AA++ LA SQL++ K+VAPT+ + C+EQL + ++V++A+ + E N+A+ +L+ + AA V ++L +++H++ ++ + L+ EN+ ++ S D ++V AR L Q T +I I+ +A +Q + + + L++AAKQLA+AT L+++A+ C+ + + + + LR+A E +T T ++ +I L +++AA+ T I+ + +A + S+ K + D + +++ I L+ ++K R P D AQL LI A +I+P+ Q+S+S++ + PTV+D T L++ EL +A C +L +ALE++++L L + + L PLP + + +A L KS + G A +Q + V++ Q SY AG R+ ++AL + GVAA+ + I++ + V ++ L+ +A+ + + QA ++ ALS +D +PGQR++D+ +++ + + P L +SEL + A E+ VS S L+ + + +Y ++ + + +E R H+ + +S +LL K I +P + L A + + +SIN+L+ + S PGQKECD + +E++R +LD P PI+ YF+C++ K+ + L ++ + K + +F S+ + DS+ L+E ++Q AYL+GV S G G+ D + I ++C + + +T Q MIS IA+++ LC + ++ S P K + K A S+L+ ++ + + +R E L + + V + Q S +F+ A IS E +++Q P+ AG V+D +E+++ +K+L + N ++ S +++++K L+ I++ APGQ +C++ L L ++ + + ++ +S+ ++ + ++ ++ + + AGK EQL ++ + MVN I A Q ++ +++E++ L+++ K+S GNP+A H ++D+ G E+ ++L ++KI+ + G V ++E +IT+ + K Q F + Q++M+ ++ +L ++ NA S L L ++TQ Y L + GA T S+ + +++ V +G+ S+++S+ RP+ A + + +E+ +++ V+ L + + GTQAC A + I D+DT+I+F + + +D F R ++ + LV + K++V+ + L +A T LA VK G L S+ + ++ + ++V +L + + SG DP Q+LKE + + ++SLLK +K+++D + + +A++ + IS+E + SP +G PE++ R+ ++ K + + + I+ N+ +IS E+ C+++ N T+ + +TL + E+Y +LL L N + + R+ + V+K + +L+ + R
Sbjct: 4 LSLRIQLEGGRVTKTIQFQPNTTVFDACKVIRDKFAEAVQGQPSEYGLFISDEQNQQGVWLEPGRTLGYYILHNQDTLEYRRKTRTLRVRMLDGAVKTILVDDSQPVSQLMVVICTKIGITNHEEYGLVREDNEAQNENLPDNKFGTLTLKRKIMEKDRDAKMESLRKKLKTDDEMNWVDVSRTLREQGIDEAETVLLRRRFFFSDQNIDSRDPVQLNLLYVQARDAILDGTHPVTQDKACEFAGIQVHIQFGPHNEAKHKTGFLDLKDFLPQSYVRT-KGIEKKIFSEHRKHVDLSEIDAKVLYTKTARELPTYGVTFFLVKEKMNGKNKLVPRLLGVTKDSVLRLDEHTKEILISWPLTTVRRWGASPNTFTLDFGDYA-NQYYSVQTTEAEQIVQLIAGYIDIILKKKQTKDHFGIEGDEGSTMVEESVAPSKATFLQHETNRM------EQLNVESLAH------------PGIMRPYDGERSYMENEVQTVQYGAFVGQVNHAHQPPTTKEVRISSVNLTEPQRALLGYISAGQDVLIRADEELRTKAPIQELGSDLRSIEWRENTLDTSKQAVSSHVATMSAATAQIITASH------------PDEVDTEAISASVSQIAQTIPEVTKEVRLIAA----LMENDTSGDQLLEAARNLCSAFSDLLKAAEPESKEP----PQHLINAASRVGEATTHVLSTIAEEE-----------------VPENRDLHDMLLALAKAVANTTAALVLRAKNIAASCDDEQARNRVIGAASQCALATSQLVACAKVVAPTLHNAACREQLEAAAKNVARAVNSLCEVCNEASNDPKLKADLLAAARDVSKSLTDMLEHVKLSSREHANRTSTELSPVENVIIGTDILVSTHDPQEMVRHARTLGQTTAQLIQSIKGEA--DQQQDADMKRHLLSAAKQLADATAKLVEAARLCSSNPHDSDNQNALRKAAEELREITTTAANTPAMKRGLIQRLEFCSKQAASAATQCISAAQNAVQHSQDHQTKETLLQDCKRVADTIPRLVTSLKTTRAQPDDPNAQLNLIEAAEQFIEPALQVSKSSRALQPTVTDIPSATQLSKGALHLGQCVSELHSVAQRARDACGGQELESALEEVRKLHDVLDDTRQAAIAGQLRPLPGQTVENTADELRKSAKNVGIALSQLLSS-----VLHNQR----SY--------AGAAGRDTALALGDFTRSVHGVAATTQ-----------------NPAIIDCADDVVTSSARLIEQAQRTLQGASNPEALTQAGREVTGALSATVDCIPGQREVDVALRNVSELSEILSMSEFPPSSRPYATL---QSELKQVAEQLSSAGGEIVVSYSSPALLAESSQNFAANYRDLLSVSMEMAGQTQEE---------EVRSHMIESLRHVSTQSCSLLSTAKSIAADPGQPNAKNLLHAAARGVTESINQLV-DASIQSAPGQKECDNAMRNIEALRLMLDYPHEPINELGYFDCVEQATGKS-RNLGYAISEMINNAKQSQHVEFSQSVNNVNDSIQGLIESSSQAAYLIGVSHPSSVAGRPGIIDQAQLTWAYQGIRQHCDIVSSQQSTKPQ----MISALTVIAKHTSYLCSICRQASMNTSNPVAKNEFIVLAKQVATATSDLVQDIKAIEEQSAGGSR---ERLVDPLLEAVKAVRQYASSSEFSSVPAKISAEGRKAQEPVIQAGRGVIDGVVEMVKAAKSLALTPDNPPVWQQLSMHSTPVSESVKRLVDNIRDKAPGQAQCEQVLHTLGTCTRELDSCALAV---NAQGLSQRRDNNLHGFSGQTMNSASELIDKLEPIRMAGKNNAEQLGHAVGEISRYVVPMVNGAIGACTHIVHSQQQMSLIQQTRSVVESAITLVQSAKESAGNPRATHAHPRLDDAIDGTREAIQELQQTVEKINAETGIVTGLMEQVNRSITRLTDKRQSLLNASYSDTFVDYQTRMVARAKEIASLANEM--NAKSSVEPSALPQLAVDMTQNYQQLTQDSVGASTTTSSPDVAMRIRTTVIDLGRSVSSMIQSSAGGARPNDAGAQKEIARSAREVSEKVAQVLAALQAGSRGTQACINAAHTVSGIIGDLDTTIMFATAGTLHSDGDGS------FADHREHILQTAKALVEDTKVLVTGAAGTQDQLANAAQNAVSTITQLAEAVKRGACSLGSTQPDSQVMVINAVKDVASALGDLINCTKLASGKSINDPSMQDLKESARVMVLNVSSLLKTVKAVEDEHTRGTRAMEATV--------------EAISQEIRAMHSPPPVGNTQVG----------PEDLIRVTMNVTAATAKAVAAGTSNLQADIVSAANLGRRAIS------EMLIVCRSVAWNCAETEELRSRTLEAGTAVGESYRDLLSGI---LHNCSADDRMHLSRRVAKCVTDLVAMAR 2292
BLAST of Talin-1 vs. Ensembl Fly
Match: rhea (gene:FBgn0260442 transcript:FBtr0333107) HSP 1 Score: 895.96 bits (2314), Expect = 0.000e+0 Identity = 686/2447 (28.03%), Postives = 1228/2447 (50.18%), Query Frame = 1
Query: 49 FELRIHIVDADVTKIVPLDPEATIFQLCETIRKNIREAQTKSPKSYGLYLPHDDLKKGLWLDNSKTLQHYILKRGDTIEYRNRSRWLHIRTMDGTNKTLKVDDSWTVSELMLTVCTKLGIYNYDEYSLI-----SDKMDFSPGIDKTLSMKRGISINXXXXXXXXXXXXYHTEDGLNWLNPSQSLRQQGIEESEVLLLKRKYFFSDMNVDSRDPIQLSLLYEQLKDAVINGTHPVTLPEAIELAGLQCQVQLGNYSADKFKPGFLDLRECLPKEYQKNPKTVEKKIFNQHSKSKDLSEVEAKEKYCLLCRSFKTYGITFFLVKEKVIGKNKLIPRLLGVNKESVVQVDEKTKEIINTWPLTSIRKWAASFNGFTMDFGEYSPDEYYTAQTDKGERISQLIAGYIDIILKRKKAKDHLGVDADEESIMYEENIAPSKAIIVEHVPKQKRSSVSEEDVVIRKKAHMANSSVRMNSQASDSVCSQDCTDFYQEDINMSR-QTSSLGRTQSPSSSLTTNSMHYRMSDDDIRQKLYIISLQDNLDTIQKYKDQLMIENKGPEIGKDEASQQWIYVNIDNSRQRMADEIGAMNAAVAQVLRSAQGLATIXXXXXXXXXXXXIAKMQNSFSLITVHLPSLMEEIRTAAYYQDQLTDEDVSGEELIAAAKRLADAFTNLIKAAYPVEDQKRSLNRKEIFDAANAVGEASSDLLQQITEQENCQIELKSERPYSIIMITEEDQLYQEELLRLAKSVANETTNLIKQVKVIAVEAENPSDQKKVVMAATETGLAISQLISTTKIVAPTIEQSVCQEQLIFSIEDVSKAIQVVVESSNKATQSEELQDLTVQAANQVQEALDTLMKHLRXXXXXXXXXXXXXXA-YENI---QEXXXXXXXXXXXXXXXRRLAQATTAMISEIQLKAVNEQYKTPEERDKLINAAKQLAEATTVLIDSAKNCTMDKDEMNLRYTLREATERFIVVTYTTECATYIQEQVIDHLLVAARKAATTGTHLINTSLSAAKKSRASNFK--VCNDGRELSNQISNLIVAIKEARRDPKDHLAQLELIAACRDYIDPSEQLSQSNKYMWPTVSDPSLQTALNQSINQSVIATEELKKCVHQADLMCQHLDLSAALEQLKRLEQNLKSIKNSIERENLIPLPDEKSDESAALLIKSVRRSGSAANQFKNDLESRCVVYEQTNGEDSYQNLENLDVAGQKARELSMALDRLVHAARGVAASIEFENQESENNDKNLEKLAQLQIVNNCLEAVKAARDLVIEAKSSPPDNDQMDRAQQASVRXXXXXXXXXXXXPGQRDLDMLSKHIESKKHQFAENRLPIQQNNNINLSNCRSELTDTTFDFNQAVNEL-VSAPSFNLVNKGCKKMRMSYDRIVEICNVLVHDPFDESDSALHHLSSNRDHIANGVMIMSEDCQTLLDKVKKIQCEPDNIIVRKQLQEATKMLLDSINRLLTNISTNLRPGQKECDKTIYRLESMRPILDNPVHPISHKDYFECLDFIIDKTVQPLADSLKNIPAAVKDENNQKFIDSIYHCADSVCMLLEETAQTAYLVGVGDVRSKIGNKGLADHTSFLQIQKEISENCQTICNPDTTARQDSSLMISTAGQIAENSRKLCEASK--TIMISFPNDKIKLSDKTKITLLAVSELMTGVQNLNQNFNEDNRKEVESLSGKVQDNVAELVQLLLSYKFAGDAAIISEEAKESQGPIKAAGITVLDTAIEVIQCSKALISSEANEELFIAYSSSCKDLNDALKHLISTIKESAPGQKECDEXXXXXXXXXXQAYDSKMKIMKHRSRTISRTFESE-ESYQNILQSALIQMPHCINELSRAGKKEPEQLARIFSRQTQLLESMVNSCICAANQTDLIQNSNIYLEHLITILEASEQLLKAVKKSGGNPKANSVHSQIDEMAQGVIESCEDLLAALDKISFKQGNVNTIVE----TITKSSAKVQESAIIPEKSRFGNSQSKMLDICYDMNNLTTDISSNANSESTQRLLAPLTQNLTQRYDDLCRACQGAVATLSNENNGKQLQECVQTVGKVSISLVKSTT-EVRPSVASSISNLQAKTQELHKRIDDVIQLLISSNVGTQACTQAIKILKEINSDIDTSILFVKSADIQNDDREYYSVKELFKKSRNSVIDNSSELVRNIKLIVSKDVCDVNILQESADQIAITSQSLANDVKVGLEHLNSSTSQYNIELLVSFQEVIVSLISFLEVARNTSGLPYTDPLFQNLKEEGKCSINAITSLLKVLKSMDDVNLKDFQAIDNAIIXXXXXXXXXXXXXXGISREASPVESPTSTNRLSIGSDITVSPRFAPEEINRLIPSLANVCDKILEISSPEFKP-IIRQENISVVSISCSKVNNELTSACKNLLRNGPVTDS-KKQTLNTVDQLVENYTELLKNFKLYLTNPTKETRIPVETVVSK-LNELIKLLR 7317
LRI + VTK + P T+F C+ IR EA P YGL++ + ++G+WL+ +TL +YIL DT+EYR ++R L +R +DG KT+ VDDS VS+LM+ +CTK+GI N++EY L+ + + TL++KR I K++ L+KK T+D +NW++ S++LR+QGI+E+E +LL+R++FFSD N+DSRDP+QL+LLY Q +DA+++GTHPVT +A E AG+Q +Q G ++ K K GFLDL++ LP+ Y + K +EKKIF++H K DLSE++AK Y R TYG+TFFLVKEK+ GKNKL+PRLLGV K+SV+++DE TKEI+ +WPLT++R+W AS N FT+DFG+Y+ ++YY+ QT + E+I QLIAGYIDIILK+K+ KDH G++ DE S M EE++APSKA ++H + E + + AH + AS + +N++ Q + LG + L +D+++R K I L +L +I +W +D S+Q ++ + M+AA AQ++ ++ +E + S S I +P + +E+R A L + D SG++L+ AA+ L AF++L+KAA P + + + +AA+ VGEA++ +L I E+E E++ + LL LAK+VAN T L+ + K IA ++ + +V+ AA++ LA SQL++ K+VAPT+ + C+EQL + ++V++A+ + E N+A+ +L+ + AA V ++L +++H++ ++ + L+ EN+ ++ S D ++V AR L Q T +I I+ +A +Q + + + L++AAKQLA+AT L+++A+ C+ + + + + LR+A E +T T ++ +I L +++AA+ T I+ + +A + S+ K + D + +++ I L+ ++K R P D AQL LI A +I+P+ Q+S+S++ + PTV+D T L++ EL +A C +L +ALE++++L L + + L PLP + + +A L KS + G A +Q + V++ Q SY AG R+ ++AL + GVAA+ + I++ + V ++ L+ +A+ + + QA ++ ALS +D +PGQR++D+ +++ + + P L +SEL + A E+ VS S L+ + + +Y ++ + + +E R H+ + +S +LL K I +P + L A + + +SIN+L+ + S PGQKECD + +E++R +LD P PI+ YF+C++ K+ + L ++ + K + +F S+ + DS+ L+E ++Q AYL+GV S G G+ D + I ++C + + +T Q MIS IA+++ LC + ++ S P K + K A S+L+ ++ + + +R E L + + V + Q S +F+ A IS E +++Q P+ AG V+D +E+++ +K+L + N ++ S +++++K L+ I++ APGQ +C++ L L ++ + + ++ +S+ ++ + ++ ++ + + AGK EQL ++ + MVN I A Q ++ +++E++ L+++ K+S GNP+A H ++D+ G E+ ++L ++KI+ + G V ++E +IT+ + K Q F + Q++M+ ++ +L ++ NA S L L ++TQ Y L + GA T S+ + +++ V +G+ S+++S+ RP+ A + + +E+ +++ V+ L + + GTQAC A + I D+DT+I+F + + +D F R ++ + LV + K++V+ + L +A T LA VK G L S+ + ++ + ++V +L + + SG DP Q+LKE + + ++SLLK +K+++D + + +A++ + IS+E + SP +G PE++ R+ ++ K + + + I+ N+ +IS E+ C+++ N T+ + +TL + E+Y +LL L N + + R+ + V+K + +L+ + R
Sbjct: 4 LSLRIQLEGGRVTKTIQFQPNTTVFDACKVIRDKFAEAVQGQPSEYGLFISDEQNQQGVWLEPGRTLGYYILHNQDTLEYRRKTRTLRVRMLDGAVKTILVDDSQPVSQLMVVICTKIGITNHEEYGLVREDNEAQNENLPDNKFGTLTLKRKIMEKDRDAKMESLRKKLKTDDEMNWVDVSRTLREQGIDEAETVLLRRRFFFSDQNIDSRDPVQLNLLYVQARDAILDGTHPVTQDKACEFAGIQVHIQFGPHNEAKHKTGFLDLKDFLPQSYVRT-KGIEKKIFSEHRKHVDLSEIDAKVLYTKTARELPTYGVTFFLVKEKMNGKNKLVPRLLGVTKDSVLRLDEHTKEILISWPLTTVRRWGASPNTFTLDFGDYA-NQYYSVQTTEAEQIVQLIAGYIDIILKKKQTKDHFGIEGDEGSTMVEESVAPSKATFLQHETNRM------EQLNVESLAH---PGIMRPYDASGHPMFYKTKEVRISSVNLTEPQRALLGYISAGQDVLI-------RADEELRTKAPIQELGSDLRSI-----------------------EWRENTLDTSKQAVSSHVATMSAATAQIITASH------------PDEVDTEAISASVSQIAQTIPEVTKEVRLIAA----LMENDTSGDQLLEAARNLCSAFSDLLKAAEPESKEP----PQHLINAASRVGEATTHVLSTIAEEE-----------------VPENRDLHDMLLALAKAVANTTAALVLRAKNIAASCDDEQARNRVIGAASQCALATSQLVACAKVVAPTLHNAACREQLEAAAKNVARAVNSLCEVCNEASNDPKLKADLLAAARDVSKSLTDMLEHVKLSSREHANRTSTELSPVENVIIGTDILVSTHDPQEMVRHARTLGQTTAQLIQSIKGEA--DQQQDADMKRHLLSAAKQLADATAKLVEAARLCSSNPHDSDNQNALRKAAEELREITTTAANTPAMKRGLIQRLEFCSKQAASAATQCISAAQNAVQHSQDHQTKETLLQDCKRVADTIPRLVTSLKTTRAQPDDPNAQLNLIEAAEQFIEPALQVSKSSRALQPTVTDIPSATQLSKGALHLGQCVSELHSVAQRARDACGGQELESALEEVRKLHDVLDDTRQAAIAGQLRPLPGQTVENTADELRKSAKNVGIALSQLLS-----SVLHNQR----SY--------AGAAGRDTALALGDFTRSVHGVAATTQ-----------------NPAIIDCADDVVTSSARLIEQAQRTLQGASNPEALTQAGREVTGALSATVDCIPGQREVDVALRNVSELSEILSMSEFPPSSRPYATL---QSELKQVAEQLSSAGGEIVVSYSSPALLAESSQNFAANYRDLLSVSMEMAGQTQEE---------EVRSHMIESLRHVSTQSCSLLSTAKSIAADPGQPNAKNLLHAAARGVTESINQLV-DASIQSAPGQKECDNAMRNIEALRLMLDYPHEPINELGYFDCVEQATGKS-RNLGYAISEMINNAKQSQHVEFSQSVNNVNDSIQGLIESSSQAAYLIGVSHPSSVAGRPGIIDQAQLTWAYQGIRQHCDIVSSQQSTKPQ----MISALTVIAKHTSYLCSICRQASMNTSNPVAKNEFIVLAKQVATATSDLVQDIKAIEEQSAGGSR---ERLVDPLLEAVKAVRQYASSSEFSSVPAKISAEGRKAQEPVIQAGRGVIDGVVEMVKAAKSLALTPDNPPVWQQLSMHSTPVSESVKRLVDNIRDKAPGQAQCEQVLHTLGTCTRELDSCALAV---NAQGLSQRRDNNLHGFSGQTMNSASELIDKLEPIRMAGKNNAEQLGHAVGEISRYVVPMVNGAIGACTHIVHSQQQMSLIQQTRSVVESAITLVQSAKESAGNPRATHAHPRLDDAIDGTREAIQELQQTVEKINAETGIVTGLMEQVNRSITRLTDKRQSLLNASYSDTFVDYQTRMVARAKEIASLANEM--NAKSSVEPSALPQLAVDMTQNYQQLTQDSVGASTTTSSPDVAMRIRTTVIDLGRSVSSMIQSSAGGARPNDAGAQKEIARSAREVSEKVAQVLAALQAGSRGTQACINAAHTVSGIIGDLDTTIMFATAGTLHSDGDGS------FADHREHILQTAKALVEDTKVLVTGAAGTQDQLANAAQNAVSTITQLAEAVKRGACSLGSTQPDSQVMVINAVKDVASALGDLINCTKLASGKSINDPSMQDLKESARVMVLNVSSLLKTVKAVEDEHTRGTRAMEATV--------------EAISQEIRAMHSPPPVGNTQVG----------PEDLIRVTMNVTAATAKAVAAGTSNLQADIVSAANLGRRAIS------EMLIVCRSVAWNCAETEELRSRTLEAGTAVGESYRDLLSGI---LHNCSADDRMHLSRRVAKCVTDLVAMAR 2271
BLAST of Talin-1 vs. Ensembl Zebrafish
Match: tln1 (talin 1 [Source:ZFIN;Acc:ZDB-GENE-031002-48]) HSP 1 Score: 989.178 bits (2556), Expect = 0.000e+0 Identity = 700/2275 (30.77%), Postives = 1194/2275 (52.48%), Query Frame = 1
Query: 55 LRIHIVDADVTKIVPLDPEATIFQLCETIRKNIREAQTKSPKSYGLYLPHDDLKKGLWLDNSKTLQHYILKRGDTIEYRNRSRWLHIRTMDGTNKTLKVDDSWTVSELMLTVCTKLGIYNYDEYSLISDKMDFSPGIDKTLSMKRGISINXXXXXXXXXXXXYHTEDGLNWLNPSQSLRQQGIEESEVLLLKRKYFFSDMNVDSRDPIQLSLLYEQLKDAVINGTHPVTLPEAIELAGLQCQVQLGNYSADKFKPGFLDLRECLPKEYQKNPKTVEKKIFNQHSKSKDLSEVEAKEKYCLLCRSFKTYGITFFLVKEKVIGKNKLIPRLLGVNKESVVQVDEKTKEIINTWPLTSIRKWAASFNGFTMDFGEYSPDEYYTAQTDKGERISQLIAGYIDIILKRKKAKDHLGVDADEESIMYEENIAPSKAIIVEH----VPKQKRSSVSEEDVVIRKKAHMANSSVRMNSQASDSVCSQDCTDFYQEDINMSRQTSSLGRTQSPSSSLTTNSMHY-RMSDDDIRQKLYIISLQDNLDTIQKYKDQLMIENKGPEIGKDEASQQWIYVNIDNSRQRMADEIGAMNAAVAQVLRSAQGLATIXXXXXXXXXXXXIAKMQNSFSLITVHLPSLMEEIRTAAYYQDQLTDEDVSGEELIAAAKRLADAFTNLIKAAYPVEDQKRSLNRKEIFDAANAVGEASSDLLQQITEQENCQIELKSERPYSIIMITEEDQLYQEELLRLAKSVANETTNLIKQVKVIAVEAENPSDQKKVVMAATETGLAISQLISTTKIVAPTIEQSVCQEQLIFSIEDVSKAIQVVVESSNKATQSEELQDLTVQAANQVQEALDTLMKHLRXXXXXXXXXXXXXXAYENIQEXX----XXXXXXXXXXXXXRRLAQATTAMISEIQLKAVNEQYKTPEERDKLINAAKQLAEATTVLIDSAKNCTMDKDEMNLRYTLREATERFIVVTYTTECATYIQEQVIDHLLVAARKAATTGTHLINTSLSAAK--KSRASNFKVCNDGRELSNQISNLIVAIKEARRDPKDHLAQLELIAACRDYIDPSEQLSQSNKYMWPTVSDPSLQTALNQSINQSVIATEELKKCVHQADLMCQHLDLSAALEQLKRLEQNLKSIKNSIERENLIPLPDEKSDESAALLIKSVRRSGSAANQFKNDLESRCVVYEQTNGEDSYQNLENLDVAGQKARELSMALDRLVHAARGVAASIEFENQESENNDKNLEKLAQLQIVNNCLEAVKAARDLVIEAKSSPPDNDQMDRAQQASVRXXXXXXXXXXXXPGQRDLDMLSKHIESKKHQFAENRLPIQQNNNINLSNCRSELTDTTFDFNQAVNELVSAPSFNL--VNKGCKKMRMSYDRIVEICNVLVHDPFDESDSALHHLSSNRDHIANGVMIMSEDCQTLLDKVKKIQCEPDNIIVRKQLQEATKMLLDSINRLLTNISTNLRPGQKECDKTIYRLESMRPILDNPVHPISHKDYFECLDFIIDKTVQPLADSLKNIPAAVKDENNQKFIDSIYHCADSVCMLLEETAQTAYLVGVGDVRSKIGNKGLADHTSFLQIQKEISENCQTICNPDTTARQDSSLMISTAGQIAENSRKLCEASK--TIMISFPNDKIKLSDKTKITLLAVSELMTGVQNLNQNFNEDNRKEVESLSGKVQDNVAELVQLLLSYKFAGDAAIISEEAKESQGPIKAAGITVLDTAIEVIQCSKALISSEANEELFIAYSSSCKDLNDALKHLISTIKESAPGQKECDEXXXXXXXXXXQAYDSKMKIMKHRSRTISRTFESEESYQNILQSALIQMPHCINELSRAGKKEPEQLARIFSRQTQLLESMVNSCICAANQTDLIQNSNIYLEHLITILEASEQLLKAVKKSGGNPKANSVHSQIDEMAQGVIESCEDLLAALDKISFKQGNVNTIVETITKSSAKVQESAIIPEKSRFGNSQSKMLDICYDMNNLTTDISSNANSESTQRLLAPLTQNLTQRYDDLCRACQGAVATLSNENNGKQLQECVQTVGKVSISLVKSTTEVR--PSVASSISNLQAKTQELHKRIDDVIQLLISSNVGTQACTQAIKILKEINSDIDTSILFVKSADIQNDDREYYSVKELFKKSRNSVIDNSSELVRNIKLIVSKDVCDVNILQESADQIAITSQSLANDVKVGLEHLNSSTSQYNIELLVSFQEVIVSLISFLEVARNTSGLPYTDPLFQNLKEEGKCSINAITSLLKVLKSMDDVNLKDFQAIDNAI 6828
L + I +V K + +P ++ C IR+ + EAQ P YGL+L DD KKG+WL+ K L +Y+L+ GDT+EY+ + R L IR +DGT KT+ VDDS VS++++T+C ++GI NYDEYSL+ D + + T ++KR ++ +D +K++KLK+K HT+D LNWL+ ++LR+QG+EESE+LLL+RK+F+SD NVDSRDP+QL+LLY Q +D ++NG+HPV+ +A E AG QCQ+Q G+++ K KPGFLDL+E LPKEY KN EK+IF H ++++E+EAK Y L RS KTYG++FFLVKEK+ GKNKL+PRLLG+ KESV++VDEKTKE+I W LT+I++WAAS FT+DFG+Y D YY+ QT +GE+I+QLIAGYIDIILK+KK+KDH G++ DEES M E++++P K+ +++ + K + SV+ +IR A S++M S + ++Q +T+ MH M Q+ ++ ++ +Q + L + P +G D ASQ W +D S+ + ++ A+ A A ++ G + I+ S L +LME DE +G++L+ AAK LA A ++++K A P + R + + AA VG+AS +LLQQI E ++ DQ +Q+ L++LAK+VAN L+ + K +A ++E+ + Q KV+ AAT+ L+ SQL++ T++VAPTI VCQEQLI + + V+K+++ VE+S+ AT E L AA V +AL+ L++H+R+ + A + I +V S D ++V AR LAQAT+ +++ I KA E E KL++AAK LA+AT ++++AK + D + LREA E + T I++++++ L AA++AA T I + AA K+ A+ ++ + +++QI L+ ++ ++ P AQL LI A ++++ P ++ + K PT+SD + L+Q A EL+ +A C L++ AL ++ LE++++ K S L PLP E ++ + L S + SA Q + E T G ++Y G AR+++ AL L AARGVAA N + L + A L + ++ + + A + P D D R Q + +S AL+ ++ LPGQRD+D + + + ++ P + N ++ L + NQ+ NELV A + K K +++ ++ + + D + + + +S LL K + +P++ ++ QL A + + DSIN+L++ + T PGQKECD + LE++ +L+NP ++ YF+C+D +++ + + L +++ I K+ N +F DS+ + ++C L E AQ AYLVGV D S G KGL D + F + ++ I CQ + +P T Q ++S A +A+++ LC A + + S P K + K + + L+ ++ ++ FN++NR++ + +G + + V L + +FA A IS E + PI AA +L+++ +IQ +++L + + + + + ++D++K LI+ ++E APGQ+ECD+A+ +L+ I++ + + + + R S E+ + +++ ++ + I ++ A + + QL S+ E ++ + I A++ Q L+ T+ E++ Q+L K++GGN KA ++E Q + E+ +DL + L +++ G V +V +IT+S K+++ + F + Q+ M+ + ++ + +N+ + L L LT + DL + A T N+ G +++ V +G LV ++ P+ + + L +++ +++ V+ L + N GTQAC A + I +D+DT+I+F + + ++ E ++ + + ++ + LV + KL+VS L ++A T LA+ VK+G L S + + L+ + ++V +L + + +G P+ DP LK K + +TSLLK +K+++D K +A++ I
Sbjct: 4 LSLKIGVGNVVKTMQFEPSTVVYDACRIIRERVPEAQLGQPSDYGLFLSDDDPKKGIWLEAGKALDYYMLRNGDTLEYKKKQRPLKIRMLDGTVKTVMVDDSKIVSDMLMTICARIGITNYDEYSLVRD-VGEEKKEETTGTLKRDKTLLRDDKKMEKLKQKLHTDDELNWLDHGRTLREQGVEESEMLLLRRKFFYSDQNVDSRDPVQLNLLYVQARDDILNGSHPVSFDKACEFAGYQCQIQFGDHNESKHKPGFLDLKEFLPKEYVKNKG--EKRIFQAHKNCQNMTEIEAKVNYVKLARSLKTYGVSFFLVKEKMKGKNKLVPRLLGITKESVMRVDEKTKEVIQEWSLTNIKRWAASPKSFTLDFGDYQ-DGYYSVQTTEGEQIAQLIAGYIDIILKKKKSKDHFGLEGDEESTMLEDSVSPKKSTVLQQQFNKMGKVETGSVALP-AIIRSGAG-GPESMKMGS------------------MPQAKQ------------HITSGQMHRGHMPPLTSAQQALTGTINSSMQAVQAVQASLDEFDALPPLGTDSASQAWRKNKMDESKHEIHSQVDAITAGTASMVNLTAGDPAETDYTAVGCAVTTISSNLTEMSKGVKLLAALME-------------DEGGNGQQLLGAAKNLACAVSDMLKTAQPSSTEPR----QNLLQAAGNVGQASGELLQQIGE-------------------SDADQHFQDMLMQLAKAVANAAAALVLKAKNVAQKSEDSAQQNKVIAAATQCALSTSQLVACTRVVAPTISSPVCQEQLIEAGKLVAKSVEGCVEASHGATGDEHLLKQVGAAATGVTQALNELLQHIRQYASGGQPIGRHGEATDRILDVTDNIFSSMGDAGEMVRQARILAQATSDLVNAI--KADAEGESDLENSRKLLSAAKLLADATARMVEAAKGAAANPDSEEQQQKLREAAEGLRMAT-NAAAQNAIKKRLVNKLENAAKQAAAAATQTIAAAQHAASSNKNPAAQQQLVQSCKVVADQIPQLVQGLRSSQAQPDSPSAQLALIGASQNFLQPGAKMVTAAKATVPTISDQASAMQLSQCAKNLASALAELRTAAQKAQEACGPLEIDNALTMVRGLERDMQEAKASAAEGKLRPLPGETLEKCSQDLGSSTKAVSSAIAQL---------LSEATQGNENY--------TGMAARDVAQALRSLASAARGVAA----------NTEDPLARNAMLDCTGDVMDKSASLIEETKRAIAKPGDPDSQQRLAQVAKAVSQALNRSVNCLPGQRDVDNAIRTVGEASKKLLSDKFPA---SGKNFQEAQANLNEAAAGLNQSANELVQASRGTTQDLAKASGKFGQDFNQFLQAGVDMAGQSQSKED---------QTQVVTNLKTISMSSSKLLLAAKALSTDPNSPNLKNQLAAAARAVTDSINQLIS-MCTQQAPGQKECDNALRELETVGGMLENPTEAVNDLGYFDCIDSVMENS-KVLGEAMAGISHNAKNSNLPEFGDSVSSASKALCGLTEAAAQGAYLVGVSDPNSHAGQKGLVDPSQFARAKQSIQMACQNLVDPACTQSQ----VLSAATIVAKHTSALCNACRLASSKTSNPVAKRQFVQSAKEVANSTANLVKSIKAIDGAFNQENRQKCKEATGPLIEAVDNLTAFASNPEFASVPAQISPEGLAAMEPITAAAKAMLESSTGLIQTARSLAVNPKDPPKWSVLAGHSRTVSDSIKKLITNMREKAPGQRECDDAIEVLSNCIREVDKASLAAISQ--QLTPRDDISHEALHEQMAASVHEISNLIEPVAIAARADASQLGHKVSQMVSYFEPLIMAAIGTASKILNSQQQMNVLDQTKTLAESALQMLYTAKETGGNHKAAHTQEALEESVQMMKEAVDDLGSTLAEVASAAGAVGGMVNSITQSINKMEDGPAFEPEGTFVDYQTTMVKTAKAIAVTVQEMVTKSNTNPDE--LGGLANQLTTEFGDLASEAKCAAMTAENDEIGSHIKKQVTELGYTCTGLVSKAGALQCSPNDSYTKKELIDSARKVSEKVSHVLAALQAGNRGTQACITAASAVSGIIADLDTTIMFATAGTLNRENAETFADHRYYIE---HILKTAKVLVEDTKLLVSGAGASQEKLAQAAQSSVNTITKLADVVKLGAASLGSEDPETQVVLINAVKDVAKALGDLISATKAAAGKPHDDPAMLQLKNSAKVMVTNVTSLLKTVKAVEDEATKGTRALEATI 2151
BLAST of Talin-1 vs. Ensembl Zebrafish
Match: tln1 (talin 1 [Source:ZFIN;Acc:ZDB-GENE-031002-48]) HSP 1 Score: 977.237 bits (2525), Expect = 0.000e+0 Identity = 703/2276 (30.89%), Postives = 1191/2276 (52.33%), Query Frame = 1
Query: 55 LRIHIVDADVTKIVPLDPEATIFQLCETIRKNIREAQTKSPKSYGLYLPHDDLKKGLWLDNSKTLQHYILKRGDTIEYRNRSRWLHIRTMDGTNKTLKVDDSWTVSELMLTVCTKLGIYNYDEYSLISDKMDFSPGIDKTLSMKRGISINXXXXXXXXXXXXYHTEDGLNWLNPSQSLRQQGIEESEVLLLKRKYFFSDMNVDSRDPIQLSLLYEQLKDAVINGTHPVTLPEAIELAGLQCQVQLGNYSADKFKPGFLDLRECLPKEYQKNPKTVEKKIFNQHSKSKDLSEVEAKEKYCLLCRSFKTYGITFFLVKEKVIGKNKLIPRLLGVNKESVVQVDEKTKEIINTWPLTSIRKWAASFNGFTMDFGEYSPDEYYTAQTDKGERISQLIAGYIDIILKRKKAKDHLGVDADEESIMYEENIAPSKAIIVEH----VPKQKRSSVSEEDVVIRKKAHMANSSVRMNSQASDSVCSQDCTDFYQEDINMSRQTSSLGRTQSPSSSLTTNSMHY-RMSDDDIRQKLYIISLQDNLDTIQKYKDQLMIENKGPEIGKDEASQQWIYVNIDNSRQRMADEIGAMNAAVAQVLRSAQGLATIXXXXXXXXXXXXIAKMQNSFSLITVHLPSLMEEIRTAAYYQDQLTDEDVSGEELIAAAKRLADAFTNLIKAAYPVEDQKRSLNRKEIFDAANAVGEASSDLLQQITEQENCQIELKSERPYSIIMITEEDQLYQEELLRLAKSVANETTNLIKQVKVIAVEAENPSDQKKVVMAATETGLAISQLISTTKIV-APTIEQSVCQEQLIFSIEDVSKAIQVVVESSNKATQSEELQDLTVQAANQVQEALDTLMKHLRXXXXXXXXXXXXXXAYENIQEXX----XXXXXXXXXXXXXRRLAQATTAMISEIQLKAVNEQYKTPEERDKLINAAKQLAEATTVLIDSAKNCTMDKDEMNLRYTLREATERFIVVTYTTECATYIQEQVIDHLLVAARKAATTGTHLINTSLSAAK--KSRASNFKVCNDGRELSNQISNLIVAIKEARRDPKDHLAQLELIAACRDYIDPSEQLSQSNKYMWPTVSDPSLQTALNQSINQSVIATEELKKCVHQADLMCQHLDLSAALEQLKRLEQNLKSIKNSIERENLIPLPDEKSDESAALLIKSVRRSGSAANQFKNDLESRCVVYEQTNGEDSYQNLENLDVAGQKARELSMALDRLVHAARGVAASIEFENQESENNDKNLEKLAQLQIVNNCLEAVKAARDLVIEAKSSPPDNDQMDRAQQASVRXXXXXXXXXXXXPGQRDLDMLSKHIESKKHQFAENRLPIQQNNNINLSNCRSELTDTTFDFNQAVNELVSAPSFNL--VNKGCKKMRMSYDRIVEICNVLVHDPFDESDSALHHLSSNRDHIANGVMIMSEDCQTLLDKVKKIQCEPDNIIVRKQLQEATKMLLDSINRLLTNISTNLRPGQKECDKTIYRLESMRPILDNPVHPISHKDYFECLDFIIDKTVQPLADSLKNIPAAVKDENNQKFIDSIYHCADSVCMLLEETAQTAYLVGVGDVRSKIGNKGLADHTSFLQIQKEISENCQTICNPDTTARQDSSLMISTAGQIAENSRKLCEASK--TIMISFPNDKIKLSDKTKITLLAVSELMTGVQNLNQNFNEDNRKEVESLSGKVQDNVAELVQLLLSYKFAGDAAIISEEAKESQGPIKAAGITVLDTAIEVIQCSKALISSEANEELFIAYSSSCKDLNDALKHLISTIKESAPGQKECDEXXXXXXXXXXQAYDSKMKIMKHRSRTISRTFESEESYQNILQSALIQMPHCINELSRAGKKEPEQLARIFSRQTQLLESMVNSCICAANQTDLIQNSNIYLEHLITILEASEQLLKAVKKSGGNPKANSVHSQIDEMAQGVIESCEDLLAALDKISFKQGNVNTIVETITKSSAKVQESAIIPEKSRFGNSQSKMLDICYDMNNLTTDISSNANSESTQRLLAPLTQNLTQRYDDLCRACQGAVATLSNENNGKQLQECVQTVGKVSISLVKSTTEVR--PSVASSISNLQAKTQELHKRIDDVIQLLISSNVGTQACTQAIKILKEINSDIDTSILFVKSADIQNDDREYYSVKELFKKSRNSVIDNSSELVRNIKLIVSKDVCDVNILQESADQIAITSQSLANDVKVGLEHLNSSTSQYNIELLVSFQEVIVSLISFLEVARNTSGLPYTDPLFQNLKEEGKCSINAITSLLKVLKSMDDVNLKDFQAIDNAI 6828
L + I +V K + +P ++ C IR+ + EAQ P YGL+L DD KKG+WL+ K L +Y+L+ GDT+EY+ + R L IR +DGT KT+ VDDS VS++++T+C ++GI NYDEYSL+ D + + T ++KR ++ +D +K++KLK+K HT+D LNWL+ ++LR+QG+EESE+LLL+RK+F+SD NVDSRDP+QL+LLY Q +D ++NG+HPV+ +A E AG QCQ+Q G+++ K KPGFLDL+E LPKEY KN EK+IF H ++++E+EAK Y L RS KTYG++FFLVKEK+ GKNKL+PRLLG+ KESV++VDEKTKE+I W LT+I++WAAS DFG+Y D YY+ QT +GE+I+QLIAGYIDIILK+KK+KDH G++ DEES M E++++P K+ +++ + K + SV+ +IR A S++M S + ++Q +T+ MH M Q+ ++ ++ +Q + L + P +G D ASQ W +D S+ + ++ A+ A A ++ G + I+ S L +LME DE +G++L+ AAK LA A ++++K A P + R + + AA VG+AS +LLQQI E ++ DQ +Q+ L++LAK+VAN L+ + K +A ++E+ + Q KV+ AAT+ L+ SQL++ T++V APTI VCQEQLI + + V+K+++ VE+S+ AT E L AA V +AL+ L++H+R+ + A + I +V S D ++V AR LAQAT+ +++ I KA E E KL++AAK LA+AT ++++AK + D + LREA E + T I++++++ L AA++AA T I + AA K+ A+ ++ + +++QI L+ ++ ++ P AQL LI A ++++ P ++ + K PT+SD + L+Q A EL+ +A C L++ AL ++ LE++++ K S L PLP E ++ + L S + SA Q + E T G ++Y G AR+++ AL L AARGVAA N + L + A L + ++ + + A + P D D R Q + +S AL+ ++ LPGQRD+D + + + ++ P + N ++ L + NQ+ NELV A + K K +++ ++ D +S S ++ + + +S LL K + +P++ ++ QL A + + DSIN+L++ + T PGQKECD + LE++ +L+NP ++ YF+C+D +++ + + L +++ I K+ N +F DS+ + ++C L E AQ AYLVGV D S G KGL D + F + ++ I CQ + +P T Q ++S A +A+++ LC A + + S P K + K + + L+ ++ L+ FN++NR++ + +G + + V L + +FA A IS E + PI AA +L+++ +IQ +++L + + + + + ++D++K LI+ ++E APGQ+ECD+A+ +L+ I++ + + + + R S E+ + +++ ++ + I ++ A + + QL S+ E ++ + I A++ Q L+ T+ E++ Q+L K++GGN KA ++E Q + E+ +DL + L +++ G V +V +IT+S K+++ + F + Q+ M+ + ++ + +N+ + L L LT + DL + A T N+ G +++ V +G LV ++ P+ + + L +++ +++ V+ L + N GTQAC A + I +D+DT+I+F + + ++ E F R ++ + LV + KL+VS L ++A T LA+ VK+G L S + + L+ + ++V +L + + +G P+ DP LK K + +TSLLK +K+++D K +A++ I
Sbjct: 4 LSLKIGVGNVVKTMQFEPSTVVYDACRIIRERVPEAQLGQPSDYGLFLSDDDPKKGIWLEAGKALDYYMLRNGDTLEYKKKQRPLKIRMLDGTVKTVMVDDSKIVSDMLMTICARIGITNYDEYSLVRD-VGEEKKEETTGTLKRDKTLLRDDKKMEKLKQKLHTDDELNWLDHGRTLREQGVEESEMLLLRRKFFYSDQNVDSRDPVQLNLLYVQARDDILNGSHPVSFDKACEFAGYQCQIQFGDHNESKHKPGFLDLKEFLPKEYVKNKG--EKRIFQAHKNCQNMTEIEAKVNYVKLARSLKTYGVSFFLVKEKMKGKNKLVPRLLGITKESVMRVDEKTKEVIQEWSLTNIKRWAAS----PKDFGDYQ-DGYYSVQTTEGEQIAQLIAGYIDIILKKKKSKDHFGLEGDEESTMLEDSVSPKKSTVLQQQFNKMGKVETGSVALP-AIIRSGAG-GPESMKMGS------------------MPQAKQ------------HITSGQMHRGHMPPLTSAQQALTGTINSSMQAVQAVQASLDEFDALPPLGTDSASQAWRKNKMDESKHEIHSQVDAITAGTASMVNLTAGDPAETDYTAVGCAVTTISSNLTEMSKGVKLLAALME-------------DEGGNGQQLLGAAKNLACAVSDMLKTAQPSSTEPR----QNLLQAAGNVGQASGELLQQIGE-------------------SDADQHFQDMLMQLAKAVANAAAALVLKAKNVAQKSEDSAQQNKVIAAATQCALSTSQLVACTRVVVAPTISSPVCQEQLIEAGKLVAKSVEGCVEASHGATGDEHLLKQVGAAATGVTQALNELLQHIRQYASGGQPIGRHGEATDRILDVTDNIFSSMGDAGEMVRQARILAQATSDLVNAI--KADAEGESDLENSRKLLSAAKLLADATARMVEAAKGAAANPDSEEQQQKLREAAEGLRMAT-NAAAQNAIKKRLVNKLENAAKQAAAAATQTIAAAQHAASSNKNPAAQQQLVQSCKVVADQIPQLVQGLRSSQAQPDSPSAQLALIGASQNFLQPGAKMVTAAKATVPTISDQASAMQLSQCAKNLASALAELRTAAQKAQEACGPLEIDNALTMVRGLERDMQEAKASAAEGKLRPLPGETLEKCSQDLGSSTKAVSSAIAQL---------LSEATQGNENY--------TGMAARDVAQALRSLASAARGVAA----------NTEDPLARNAMLDCTGDVMDKSASLIEETKRAIAKPGDPDSQQRLAQVAKAVSQALNRSVNCLPGQRDVDNAIRTVGEASKKLLSDKFPA---SGKNFQEAQANLNEAAAGLNQSANELVQASRGTTQDLAKASGKFGQDFNQFLQAG----VDMAGQSQS-----KEDQTQVVTNLKTISMSSSKLLLAAKALSTDPNSPNLKNQLAAAARAVTDSINQLIS-MCTQQAPGQKECDNALRELETVGGMLENPTEAVNDLGYFDCIDSVMENS-KVLGEAMAGISHNAKNSNLPEFGDSVSSASKALCGLTEAAAQGAYLVGVSDPNSHAGQKGLVDPSQFARAKQSIQMACQNLVDPACTQSQ----VLSAATIVAKHTSALCNACRLASSKTSNPVAKRQFVQSAKEVANSTANLVKSIKALDGAFNQENRQKCKEATGPLIEAVDNLTAFASNPEFASVPAQISPEGLAAMEPITAAAKAMLESSTGLIQTARSLAVNPKDPPKWSVLAGHSRTVSDSIKKLITNMREKAPGQRECDDAIEVLSNCIREVDKASLAAISQ--QLTPRDDISHEALHEQMAASVHEISNLIEPVAIAARADASQLGHKVSQMVSYFEPLIMAAIGTASKILNSQQQMNVLDQTKTLAESALQMLYTAKETGGNHKAAHTQEALEESVQMMKEAVDDLGSTLAEVASAAGAVGGMVNSITQSINKMEDGPAFEPEGTFVDYQTTMVKTAKAIAVTVQEMVTKSNTNPDE--LGGLANQLTTEFGDLASEAKCAAMTAENDEIGSHIKKQVTELGYTCTGLVSKAGALQCSPNDSYTKKELIDSARKVSEKVSHVLAALQAGNRGTQACITAASAVSGIIADLDTTIMFATAGTLNREN------AETFADHREHILKTAKVLVEDTKLLVSGAGASQEKLAQAAQSSVNTITKLADVVKLGAASLGSEDPETQVVLINAVKDVAKALGDLISATKAAAGKPHDDPAMLQLKNSAKVMVTNVTSLLKTVKAVEDEATKGTRALEATI 2145
BLAST of Talin-1 vs. Ensembl Zebrafish
Match: tln2a (talin 2a [Source:ZFIN;Acc:ZDB-GENE-040724-263]) HSP 1 Score: 922.924 bits (2384), Expect = 0.000e+0 Identity = 702/2291 (30.64%), Postives = 1178/2291 (51.42%), Query Frame = 1
Query: 49 FELRIHIVDADVTKIVPLDPEATIFQLCETIRKNIREAQTKSPKSYGLYLPHDDLKKGLWLDNSKTLQHYILKRGDTIEYRNRSRWLHIRTMDGTNKTLKVDDSWTVSELMLTVCTKLGIYNYDEYSLISDKMDFSPGIDKTLSMKRGISINXXXXXXXXXXXXYHTEDGLNWLNPSQSLRQQGIEESEVLLLKRKYFFSDMNVDSRDPIQLSLLYEQLKDAVINGTHPVTLPEAIELAGLQCQVQLGNYSADKFKPGFLDLRECLPKEYQKNPKTVEKKIFNQHSKSKDLSEVEAKEKYCLLCRSFKTYGITFFLVKEKVIGKNKLIPRLLGVNKESVVQVDEKTKEIINTWPLTSIRKWAASFNGFTMDFGEYSPDEYYTAQTDKGERISQLIAGYIDIILKRKKAKDHLGVDADEESIMYEENIAPSKAIIVEH----VPKQKRSSVSEEDVVIRKKAHMANSSVRMNSQASDSVCSQDCTDFYQEDINMSRQTSSLGRTQSPSSSLTTNSMHY-RMSDDDIRQKLYIISLQDNLDTIQKYKDQLMIENKGPEIGKDEASQQWIYVNIDNSRQRMADEIGAMNAAVAQVLRSAQGLATIXXXXXXXXXXXXIAKMQNSFSLITVHLPSLMEEIRTAAYYQDQLTDEDVSGEELIAAAKRLADAFTNLIKAAYPVEDQKRSLNRKEIFDAANAVGEASSDLLQQITEQENCQIELKSERPYSIIMITEEDQLYQEELLRLAKSVANETTNLIKQVKVIAVEAENPSDQKKVVMAATETGLAISQLISTTKIVAPTIEQSVCQEQLIFSIEDVSKAIQVVVESSNKATQSEELQDLTVQAANQVQEALDTLMKHLRXXXXXXXXXXXXXXAYENI----QEXXXXXXXXXXXXXXXRRLAQATTAMISEIQLKAVNEQYKTPEERDKLINAAKQLAEATTVLIDSAKNCTMDKDEMNLRYTLREATERFIVVTYTTECATYIQEQVIDHL--LVAARKAATTGTHLINTSLSAAKKSRASNFKVCNDGRELSNQISNLIVAIKEARRDPKDHLAQLELIAACRDYIDPSEQLSQSNKYMWPTVSDPSLQTALNQSINQSVIATEELKKCVHQADLMCQHLDLSAALEQLKRLEQNLKSIKNSIERENLIPLPDEKSDESAALLIKSVRRSGSAANQFKNDLESRCVVYEQTNGEDSYQNLENLDVAGQKARELSMALDRLVHAARGVAASIEFENQESENNDKNLEKLAQLQIVNNCLEAVKAARDLVIEAKS---SPPDNDQMDRAQQASVRXXXXXXXXXXXXPGQRDLDMLSKHI-ESKKHQFAENRLPIQQNNNINLSNCRSELTDTTFDFNQAVNELVSAPSFNLVNKGCKKMRMSYDRIVEICNVLVHDPFDES-DSALH---HLSSNRD--HIANGVMIMSEDCQTLLDKVKKIQCEPDNIIVRKQLQEATKMLLDSINRLLTNISTNLRPGQKECDKTIYRLESMRPILDNPVHPISHKDYFECLDFIIDKTVQPLADSLKNIPAAVKDENNQKFIDSIYHCADSVCMLLEETAQTAYLVGVGDVRSKIGNKGLADHTSFLQIQKEISENCQTICNPDTTARQDSSLMISTAGQIAENSRKLCEASK--TIMISFPNDKIKLSDKTKITLLAVSELMTGVQNLNQNFNEDNRKEVESLSGKVQDNVAELVQLLLSYKFAGDAAIISEEAKESQGPIKAAGITVLDTAIEVIQCSKALISSEANEELFIAYSSSCKDLNDALKHLISTIKESAPGQKECDEXXXXXXXXXXQAYDSKMKIMKHRSRTISRTFE-SEESYQNILQSALIQMPHCINELSRAGKKEPEQLARIFSRQTQLLESMVNSCICAANQT-DLIQNSNIYLEHLITILEASEQLLKAVKKSGGNPKANSVHSQIDEMAQGVIESCEDLLAALDKISFKQGNVNTIVETITKSSAKVQESAIIPEKSRFGNSQSKML----DICYDMNNLTTDISSNANSESTQRLLAPLTQNLTQRYDDLCRACQGAVATLSNENNGKQLQECVQTVGKVSISLVK--STTEVRPSVASSISNLQAKTQELHKRIDDVIQLLISSNVGTQACTQAIKILKEINSDIDTSILFVKSADIQNDDREYYSVKELFKKSRNSVIDNSSELVRNIKLIVSKDVCDVNILQESADQIAITSQSLANDVKVGLEHLNSSTSQYNIELLVSFQEVIVSLISFLEVARNTSGLPYTDPLFQNLKEEGKCSINAITSLLKVLKSMDDVNLKDFQAIDNAI 6828
L+I + +V K + +P ++ C IR+ + EAQT YGL+L +D +KG+WL+ +TL +Y+L+ GD +EY+ + R ++ +DG KT+ VDDS TV EL++T+C+++GI NY+EYSLI + ++ + T ++K+ ++ +++ K++KLK K HT+D LNWL+ ++ R+QG+EESE LLL+RK+F+SD NVDSRDP+QL+LLY Q +D ++NG+HPV+ +A E G+Q Q+Q G + K K GFLDL+E LPKEY K + EKKIF +H +++E+EAK KY L RS +TYG++FFLVKEK+ KNKL+PRLLGV KESV++VDEKTK+++ WPLT++++WAAS FT+DFGEY + YY+ QT +GE+ISQLIAGYIDIILK+K++KD G++ DEE+ M EE+++P K+ I++ V + + SV+ ++ S SV + E +NM G +P +TT MH M Q+ + ++ ++ +Q+ +D L + P +G D AS+ WI +D S+ + ++ A+ A A V+ G T + I+ S L +LME DE SG +L+ AA+ L A ++L+KA P + R+ + AA ++G+AS DLL+QI E E D+ +Q+ L+ LAK+VAN ++ + K +A +E+ Q +V+ AAT+ L+ SQL++ K+V+PTI VCQEQLI + + V ++++ V++ AT EL AA V +AL L+ H+R + + + + A + I + + S D ++V AR LAQAT+ +++ ++ A E KL+ AAK LA+AT ++++AK + + + LREA E V T I++++I L AA T T + + +A+ K+ A++ ++ R +++ I L+ ++ ++ P+D AQL LI A ++++ P ++ S K PTV+D + L Q EL+ A C +++ +AL ++ L+ L+ K + L PLP E ++ A L + + GS+ Q C G + Y G A E + AL L AARGVAA+ + ++++ E ++ + L+ EAK +P D + R Q + +S +L+ C++ LPGQ+D+DM K I E+ K E P + + +S+L T D NQ+ ++V A R + ++ + D FDE D+ + H D + + +S LL K + +P + L A + + DSIN+L+T + N PGQ+ECD + LE++R +LDNP P++ YF+C++ +++ + + L +S+ I K + F D + + ++C L E Q +YLVGV D S+ G+ GL D F + + I CQ + +PD++ Q ++S A +A+++ LC A + + + P K K + + L+ ++ L+ +F+E+NR++ + + + V L + +FA A IS E +Q PI + ++LD++ +++ +++L+ + + + + + ++D++K LI+ I++ APGQKECD A+ + K I D + + S+ + R E S E+ Q L S++ ++ H I ++ A K E QL S+ +V++ + A++T D Q N+ L+ T+ E++ Q+L A K+ GGNPKA+ H I E AQ + E+ +DLL L++ + + G V+ +V++I S K+ E + F Q+ M+ I + T S S+ L L +T Y L + A AT E G Q++ VQ +G I LV+ ++ P+ + + L + + +++ V+ L + N GTQAC A + I +D+DT+I+F SA N + + S F R +++ + LV + K +VS L ++A A T L + VK+G + + + L+ + ++V +L + + +G DP LK K + +TSLLK +K+++D + +A++ I
Sbjct: 4 LSLKICVRQCNVVKTMQFEPSTAVYDACRVIRERVPEAQTGQASEYGLFLSDEDPRKGIWLEGGRTLDYYMLRNGDILEYKKKQRPQKVKMLDGAVKTIMVDDSKTVGELLVTICSRIGITNYEEYSLIQETVEEKKD-EGTGTLKKDRTLLREERKMEKLKAKLHTDDDLNWLDHGRTFREQGVEESETLLLRRKFFYSDQNVDSRDPVQLNLLYVQARDDILNGSHPVSFDKACEFGGIQTQIQFGPHIEHKHKTGFLDLKEFLPKEYIKQ-RGAEKKIFQEHKGCGEMTEIEAKVKYVKLARSLRTYGVSFFLVKEKMKSKNKLVPRLLGVTKESVMRVDEKTKDVVQEWPLTTVKRWAASPKSFTLDFGEYQ-ESYYSVQTTEGEQISQLIAGYIDIILKKKQSKDRFGLEGDEEATMLEESVSPKKSTILQQQFNRVGRVEHGSVALPGIL-----------------RSGSVGA--------ETLNM-------GTMPAPQQQITTGQMHLGHMPPLSAAQQALVGTINTSMQAVQQAQDDLEEVEELPPLGDDMASKMWIQNKMDESKHDIHSQVDAITAGTASVVNLTAGDPTDTDYTAVGCAITTISSNLTEMSKGVKLLAALME-------------DEVGSGHDLMRAARTLTGAVSDLLKAVEPTSGEP----RQTVLTAAGSIGQASGDLLRQIGENET-------------------DERFQDVLMNLAKAVANAAAMMVLKAKNVAQVSEDSVMQNRVIAAATQCALSTSQLVACAKVVSPTISSPVCQEQLIEAGKLVDRSVEGCVKACLSATSDGELLKAVSAAAGIVTQALSDLLTHVRNYATRGEPIGRYDQATDTIMNVTENIFSSMGDAGEMVRQARVLAQATSDLVNAMRSDA--EVEVDVNNSKKLLAAAKLLADATARMVEAAKGAAAYPENEDQQQKLREAAEGLRVAT-NAAAQNAIKKKLITRLENAAKQAAAAATQTIAASQNAAASNKNTAAHQQLVQSCRAVADHIPQLVQGVRGSQGQPEDGSAQLALIIASKNFLQPGSKMVSSAKSSVPTVTDQAAAMQLGQCAKNLATTLAELRTAAQTAHEACGPMEIDSALIAVQTLKNELQDAKMAASEGQLKPLPGESLEKCAQDLGGTSKAVGSSMAQLLT-----CAA----QGNEHY--------TGVAASETAQALKTLAQAARGVAATTS-------------DPAGAAAMLDSAREVMEGSAKLISEAKEALVAPGDAEIQQRLAQVAKAVSHSLNACVNCLPGQKDVDMALKSIGEASKKLLVETLPPCSK----SFQEAQSDLNQTAADLNQSAGDVVHAS------------RGTTTQLADASGKF-SDNFDEFLDAGIEMAGHTPGKDDQLQVIGNLKNISMASSKLLLAAKSLSVDPGAGNAKNLLAAAARSVTDSINQLITMCTQNA-PGQRECDNALRELEAVRGLLDNPNEPVNDLSYFDCIESVMENS-KVLGESMAGISHNCKTGDVPAFGDCVGGASKALCGLTEAAGQASYLVGVSDPSSQAGHPGLVDPIQFARANQAIQMACQNLVDPDSSPSQ----VLSAATIVAKHTSALCNACRLASSKTANPVAKRHFVQSAKEVANSTANLVKTIKALDGDFSEENREKCRIATAPLIEAVDNLTIFASNPEFASVPAQISREGSAAQEPIIQSARSMLDSSTHLLKTARSLVMNPKDPPTWSLLAGHSRTVSDSIKSLITAIRDKAPGQKECDSAIDNINKCI---RDIEQASLAAVSQNLPRRDEVSSEALQEQLTSSVQEVGHLIEPITTAAKGEAAQLGHKVSQLVSYFTPLVSASMGIASKTLDHQQQMNL-LDQTKTLAESALQMLYAAKEGGGNPKASHTHDAIAEAAQLMREAVDDLLLTLNEAASEVGMVSGMVDSIADSMGKLGEGTPPEPEGSFVEYQTTMVRYSKAIAVSAQEMIT------KSVSSPEDLCSLASQVTADYSQLAVQGRLASATAEPEEIGFQIKTSVQELGHGCIVLVQKAGALQISPTDSFTKRELIECARAVTEKVSMVLSALQAGNKGTQACITAASAVSGIIADLDTTIMFA-SAGTLNAENDSDS----FADHRENILKTAKALVEDTKNLVSGAASSQEKLAQAAQSSAKTITQLTDVVKLGAASIGPDDPETQVVLINAVKDVAKALAELISATKCAAGKAADDPSMFQLKSAAKVMVTNVTSLLKTVKAVEDEASRGTRALEATI 2152
BLAST of Talin-1 vs. Ensembl Zebrafish
Match: tln2a (talin 2a [Source:ZFIN;Acc:ZDB-GENE-040724-263]) HSP 1 Score: 917.531 bits (2370), Expect = 0.000e+0 Identity = 700/2290 (30.57%), Postives = 1176/2290 (51.35%), Query Frame = 1
Query: 49 FELRIHIVDADVTKIVPLDPEATIFQLCETIRKNIREAQTKSPKSYGLYLPHDDLKKGLWLDNSKTLQHYILKRGDTIEYRNRSRWLHIRTMDGTNKTLKVDDSWTVSELMLTVCTKLGIYNYDEYSLISDKMDFSPGIDKTLSMKRGISINXXXXXXXXXXXXYHTEDGLNWLNPSQSLRQQGIEESEVLLLKRKYFFSDMNVDSRDPIQLSLLYEQLKDAVINGTHPVTLPEAIELAGLQCQVQLGNYSADKFKPGFLDLRECLPKEYQKNPKTVEKKIFNQHSKSKDLSEVEAKEKYCLLCRSFKTYGITFFLVKEKVIGKNKLIPRLLGVNKESVVQVDEKTKEIINTWPLTSIRKWAASFNGFTMDFGEYSPDEYYTAQTDKGERISQLIAGYIDIILKRKKAKDHLGVDADEESIMYEENIAPSKAIIVEH----VPKQKRSSVSEEDVVIRKKAHMANSSVRMNSQASDSVCSQDCTDFYQEDINMSRQTSSLGRTQSPSSSLTTNSMHY-RMSDDDIRQKLYIISLQDNLDTIQKYKDQLMIENKGPEIGKDEASQQWIYVNIDNSRQRMADEIGAMNAAVAQVLRSAQGLATIXXXXXXXXXXXXIAKMQNSFSLITVHLPSLMEEIRTAAYYQDQLTDEDVSGEELIAAAKRLADAFTNLIKAAYPVEDQKRSLNRKEIFDAANAVGEASSDLLQQITEQENCQIELKSERPYSIIMITEEDQLYQEELLRLAKSVANETTNLIKQVKVIAVEAENPSDQKKVVMAATETGLAISQLISTTKIVAPTIEQSVCQEQLIFSIEDVSKAIQVVVESSNKATQSEELQDLTVQAANQVQEALDTLMKHLRXXXXXXXXXXXXXXAYENI----QEXXXXXXXXXXXXXXXRRLAQATTAMISEIQLKAVNEQYKTPEERDKLINAAKQLAEATTVLIDSAKNCTMDKDEMNLRYTLREATERFIVVTYTTECATYIQEQVIDHL--LVAARKAATTGTHLINTSLSAAKKSRASNFKVCNDGRELSNQISNLIVAIKEARRDPKDHLAQLELIAACRDYIDPSEQLSQSNKYMWPTVSDPSLQTALNQSINQSVIATEELKKCVHQADLMCQHLDLSAALEQLKRLEQNLKSIKNSIERENLIPLPDEKSDESAALLIKSVRRSGSAANQFKNDLESRCVVYEQTNGEDSYQNLENLDVAGQKARELSMALDRLVHAARGVAASIEFENQESENNDKNLEKLAQLQIVNNCLEAVKAARDLVIEAKS---SPPDNDQMDRAQQASVRXXXXXXXXXXXXPGQRDLDMLSKHIESKKHQFAENRLPIQQNNNINLSNCRSELTDTTFDFNQAVNELVSAPSFNLVNKGCKKMRMSYDRIVEICNVLVHDPFDES-DSALH---HLSSNRD--HIANGVMIMSEDCQTLLDKVKKIQCEPDNIIVRKQLQEATKMLLDSINRLLTNISTNLRPGQKECDKTIYRLESMRPILDNPVHPISHKDYFECLDFIIDKTVQPLADSLKNIPAAVKDENNQKFIDSIYHCADSVCMLLEETAQTAYLVGVGDVRSKIGNKGLADHTSFLQIQKEISENCQTICNPDTTARQDSSLMISTAGQIAENSRKLCEASK--TIMISFPNDKIKLSDKTKITLLAVSELMTGVQNLNQNFNEDNRKEVESLSGKVQDNVAELVQLLLSYKFAGDAAIISEEAKESQGPIKAAGITVLDTAIEVIQCSKALISSEANEELFIAYSSSCKDLNDALKHLISTIKESAPGQKECDEXXXXXXXXXXQAYDSKMKIMKHRSRTISRTFE-SEESYQNILQSALIQMPHCINELSRAGKKEPEQLARIFSRQTQLLESMVNSCICAANQT-DLIQNSNIYLEHLITILEASEQLLKAVKKSGGNPKANSVHSQIDEMAQGVIESCEDLLAALDKISFKQGNVNTIVETITKSSAKVQESAIIPEKSRFGNSQSKML----DICYDMNNLTTDISSNANSESTQRLLAPLTQNLTQRYDDLCRACQGAVATLSNENNGKQLQECVQTVGKVSISLVK--STTEVRPSVASSISNLQAKTQELHKRIDDVIQLLISSNVGTQACTQAIKILKEINSDIDTSILFVKSADIQNDDREYYSVKELFKKSRNSVIDNSSELVRNIKLIVSKDVCDVNILQESADQIAITSQSLANDVKVGLEHLNSSTSQYNIELLVSFQEVIVSLISFLEVARNTSGLPYTDPLFQNLKEEGKCSINAITSLLKVLKSMDDVNLKDFQAIDNAI 6828
L+I + +V K + +P ++ C IR+ + EAQT YGL+L +D +KG+WL+ +TL +Y+L+ GD +EY+ + R ++ +DG KT+ VDDS TV EL++T+C+++GI NY+EYSLI + ++ + T ++K+ ++ +++ K++KLK K HT+D LNWL+ ++ R+QG+EESE LLL+RK+F+SD NVDSRDP+QL+LLY Q +D ++NG+HPV+ +A E G+Q Q+Q G + K K GFLDL+E LPKEY K + EKKIF +H +++E+EAK KY L RS +TYG++FFLVKEK+ KNKL+PRLLGV KESV++VDEKTK+++ WPLT++++WAAS FT+DFGEY + YY+ QT +GE+ISQLIAGYIDIILK+K++KD G++ DEE+ M EE+++P K+ I++ V + + SV+ ++ S SV + E +NM G +P +TT MH M Q+ + ++ ++ +Q+ +D L + P +G D AS+ WI +D S+ + ++ A+ A A V+ G T + I+ S L +LME DE SG +L+ AA+ L A ++L+KA P + R+ + AA ++G+AS DLL+QI E E D+ +Q+ L+ LAK+VAN ++ + K +A +E+ Q +V+ AAT+ L+ SQL++ K+V+PTI VCQEQLI + + V ++++ V++ AT EL AA V +AL L+ H+R + + + + A + I + + S D ++V AR LAQAT+ +++ ++ A E KL+ AAK LA+AT ++++AK + + + LREA E V T I++++I L AA T T + + +A+ K+ A++ ++ R +++ I L+ ++ ++ P+D AQL LI A ++++ P ++ S K PTV+D + L Q EL+ A C +++ +AL ++ L+ L+ K + L PLP E ++ A L + + GS+ Q C G + Y G A E + AL L AARGVAA+ + ++++ E ++ + L+ EAK +P D + R Q + +S +L+ C++ LPGQ+D+DM K I + LP + + +S+L T D NQ+ ++V A R + ++ + D FDE D+ + H D + + +S LL K + +P + L A + + DSIN+L+T + N PGQ+ECD + LE++R +LDNP P++ YF+C++ +++ + + L +S+ I K + F D + + ++C L E Q +YLVGV D S+ G+ GL D F + + I CQ + +PD++ Q ++S A +A+++ LC A + + + P K K + + L+ ++ L+ +F+E+NR++ + + + V L + +FA A IS E +Q PI + ++LD++ +++ +++L+ + + + + + ++D++K LI+ I++ APGQKECD A+ + K I D + + S+ + R E S E+ Q L S++ ++ H I ++ A K E QL S+ +V++ + A++T D Q N+ L+ T+ E++ Q+L A K+ GGNPKA+ H I E AQ + E+ +DLL L++ + + G V+ +V++I S K+ E + F Q+ M+ I + T S S+ L L +T Y L + A AT E G Q++ VQ +G I LV+ ++ P+ + + L + + +++ V+ L + N GTQAC A + I +D+DT+I+F SA N + + S F R +++ + LV + K +VS L ++A A T L + VK+G + + + L+ + ++V +L + + +G DP LK K + +TSLLK +K+++D + +A++ I
Sbjct: 4 LSLKICVRQCNVVKTMQFEPSTAVYDACRVIRERVPEAQTGQASEYGLFLSDEDPRKGIWLEGGRTLDYYMLRNGDILEYKKKQRPQKVKMLDGAVKTIMVDDSKTVGELLVTICSRIGITNYEEYSLIQETVEEKKD-EGTGTLKKDRTLLREERKMEKLKAKLHTDDDLNWLDHGRTFREQGVEESETLLLRRKFFYSDQNVDSRDPVQLNLLYVQARDDILNGSHPVSFDKACEFGGIQTQIQFGPHIEHKHKTGFLDLKEFLPKEYIKQ-RGAEKKIFQEHKGCGEMTEIEAKVKYVKLARSLRTYGVSFFLVKEKMKSKNKLVPRLLGVTKESVMRVDEKTKDVVQEWPLTTVKRWAASPKSFTLDFGEYQ-ESYYSVQTTEGEQISQLIAGYIDIILKKKQSKDRFGLEGDEEATMLEESVSPKKSTILQQQFNRVGRVEHGSVALPGIL-----------------RSGSVGA--------ETLNM-------GTMPAPQQQITTGQMHLGHMPPLSAAQQALVGTINTSMQAVQQAQDDLEEVEELPPLGDDMASKMWIQNKMDESKHDIHSQVDAITAGTASVVNLTAGDPTDTDYTAVGCAITTISSNLTEMSKGVKLLAALME-------------DEVGSGHDLMRAARTLTGAVSDLLKAVEPTSGEP----RQTVLTAAGSIGQASGDLLRQIGENET-------------------DERFQDVLMNLAKAVANAAAMMVLKAKNVAQVSEDSVMQNRVIAAATQCALSTSQLVACAKVVSPTISSPVCQEQLIEAGKLVDRSVEGCVKACLSATSDGELLKAVSAAAGIVTQALSDLLTHVRNYATRGEPIGRYDQATDTIMNVTENIFSSMGDAGEMVRQARVLAQATSDLVNAMRSDA--EVEVDVNNSKKLLAAAKLLADATARMVEAAKGAAAYPENEDQQQKLREAAEGLRVAT-NAAAQNAIKKKLITRLENAAKQAAAAATQTIAASQNAAASNKNTAAHQQLVQSCRAVADHIPQLVQGVRGSQGQPEDGSAQLALIIASKNFLQPGSKMVSSAKSSVPTVTDQAAAMQLGQCAKNLATTLAELRTAAQTAHEACGPMEIDSALIAVQTLKNELQDAKMAASEGQLKPLPGESLEKCAQDLGGTSKAVGSSMAQLLT-----CAA----QGNEHY--------TGVAASETAQALKTLAQAARGVAATTS-------------DPAGAAAMLDSAREVMEGSAKLISEAKEALVAPGDAEIQQRLAQVAKAVSHSLNACVNCLPGQKDVDMALKSIGEASKKL---LLP---PCSKSFQEAQSDLNQTAADLNQSAGDVVHAS------------RGTTTQLADASGKF-SDNFDEFLDAGIEMAGHTPGKDDQLQVIGNLKNISMASSKLLLAAKSLSVDPGAGNAKNLLAAAARSVTDSINQLITMCTQNA-PGQRECDNALRELEAVRGLLDNPNEPVNDLSYFDCIESVMENS-KVLGESMAGISHNCKTGDVPAFGDCVGGASKALCGLTEAAGQASYLVGVSDPSSQAGHPGLVDPIQFARANQAIQMACQNLVDPDSSPSQ----VLSAATIVAKHTSALCNACRLASSKTANPVAKRHFVQSAKEVANSTANLVKTIKALDGDFSEENREKCRIATAPLIEAVDNLTIFASNPEFASVPAQISREGSAAQEPIIQSARSMLDSSTHLLKTARSLVMNPKDPPTWSLLAGHSRTVSDSIKSLITAIRDKAPGQKECDSAIDNINKCI---RDIEQASLAAVSQNLPRRDEVSSEALQEQLTSSVQEVGHLIEPITTAAKGEAAQLGHKVSQLVSYFTPLVSASMGIASKTLDHQQQMNL-LDQTKTLAESALQMLYAAKEGGGNPKASHTHDAIAEAAQLMREAVDDLLLTLNEAASEVGMVSGMVDSIADSMGKLGEGTPPEPEGSFVEYQTTMVRYSKAIAVSAQEMIT------KSVSSPEDLCSLASQVTADYSQLAVQGRLASATAEPEEIGFQIKTSVQELGHGCIVLVQKAGALQISPTDSFTKRELIECARAVTEKVSMVLSALQAGNKGTQACITAASAVSGIIADLDTTIMFA-SAGTLNAENDSDS----FADHRENILKTAKALVEDTKNLVSGAASSQEKLAQAAQSSAKTITQLTDVVKLGAASIGPDDPETQVVLINAVKDVAKALAELISATKCAAGKAADDPSMFQLKSAAKVMVTNVTSLLKTVKAVEDEASRGTRALEATI 2149
BLAST of Talin-1 vs. Ensembl Zebrafish
Match: mast1a (microtubule associated serine/threonine kinase 1a [Source:ZFIN;Acc:ZDB-GENE-121214-221]) HSP 1 Score: 643.269 bits (1658), Expect = 0.000e+0 Identity = 323/614 (52.61%), Postives = 417/614 (67.92%), Query Frame = 1
Query: 9565 IKPRSQSLNPCRSPGAYEQDIFILNHVYKERFPKATIQMMERLSAMLEELENENTVSW-EPISRLVHTQIMKHVKDILNMTNLEAITSTYFFELTQNLEKLLKETRLKCPES-LARVRPIVQHLLFIIARPARLLECIEFDPKEFYKLLEVAENNLRNVQ---TDVPKYIISKLGLDKDPYDIGSEELNTSLELNGGSLEIXXXXXXXXXXXXXXXXXLNMSQESNNSLELSFSKSMTPKESDFEDIKLISNGAYGAVHLVREKKTKKRFAMKKIRKDNLLLRNQVEQIFAERDIMTFADSPFVVGLYCTFETRKYLCMIMEYVEGGDVATLIKSIGPLPDELARMYFAETVLALEYLHNFGIVHRDLKPDNLLITLEGHIKLTDFGLSKVGLMNLTTTLLESVLNKDCTMFQDKQVFGTPDYIAPEVILRQGYDKMIDWWAMGIILYEFIVGCTPFYGDSTEELFGNIISGEIEWPQDPDPCVPDNAVNLITELLKRDPLVRLGAEGTHEVKEHEFFSDVDWQGLLRQKALFIPVLDHEDDTSYFDPRTSRYQHESESDDPDPGSGLGSXXXXXXNDETIEHCEXXXXXXXXXXXXXGTVFHAFPSCSPRFSR 11391
++PRS+SL+P RS Y+ +I ++NHVYKERFPKAT QM ERL+ +E EN + + + +H QI + ++ L + IT+ YF+EL +NLEKLL E + S L + +V+ L II+RPARLLEC+EF+P+EFY LLE AE++ + Q D+P+YIIS+LGL +DP + + +N + G + E+++S E P ESDF+ IKLISNGAYGAV+LVR ++T++RFAMKKI K NL+LRNQ++Q F ERDI+TFA++PFVV ++C+FETR++LCM+MEYVEGGD ATL+K+IG LP ++ARMYFAETVLALEY+HN+GIVHRDLKPDNLLIT GHIKLTDFGLSK+GLMNLTT L E + KD F DKQV GTP+YIAPEVILRQGY K +DWWAMGIILYEF+VGC PF+GD+ EELFG +I+ IEWP D +P +A +LI+ LL+ +PLVRLG G EVK+H FFS +DW GLLRQKA FIP L+ E+DTSYFD R+ RY+H + D+ D +DE +E F SCSPRFS+
Sbjct: 131 MRPRSRSLSPGRSSSCYDNEIVMMNHVYKERFPKATAQMEERLADFIESYSPENVLPLADGVLSFIHHQIAELSRNCLTKSREGLITTVYFYELQENLEKLLHEAYERSESSELTFITELVKKLFIIISRPARLLECLEFNPEEFYHLLEAAEDHAKEGQLMKADIPRYIISQLGLTRDPLE---DMVNLESYDSEGP----------------------HTPETDDSAEGKLKAIKPPCESDFQTIKLISNGAYGAVYLVRHRETRQRFAMKKINKQNLILRNQIQQAFVERDILTFAENPFVVSMFCSFETRRHLCMVMEYVEGGDCATLLKNIGALPVDMARMYFAETVLALEYIHNYGIVHRDLKPDNLLITSMGHIKLTDFGLSKMGLMNLTTNLYEGHIEKDAREFLDKQVCGTPEYIAPEVILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVITDYIEWPNG-DEALPADAQSLISSLLQTNPLVRLGTGGAFEVKQHSFFSGLDWNGLLRQKAEFIPHLESEEDTSYFDTRSERYRHINSYDEDD-----------TNDDEPVE-------------------IRQFSSCSPRFSK 688 HSP 2 Score: 98.5969 bits (244), Expect = 1.930e-19 Identity = 44/99 (44.44%), Postives = 67/99 (67.68%), Query Frame = 1
Query: 12130 IVIHRRSRNFGFVIRAIRVFYGESNVYTLHHLIVGVDPEGSAFQAGLREGDLITHINGVSIVGAYHTEVVSMIIQSGASISLRVIPINKSFIRTDGPWR 12426
I I R + +GF +RAIRV+ G+++VY++HH++ V+ G A +AGL GDLITH+NG S+ G HTEVV +I++SG +++ P + I+ GP R
Sbjct: 952 ITIQRSGKKYGFTLRAIRVYIGDTDVYSVHHIVWHVEDGGPAQEAGLCAGDLITHVNGESVHGLVHTEVVELILKSGNKVTVTTTPFENTSIKV-GPAR 1049
BLAST of Talin-1 vs. Ensembl Xenopus
Match: TLN2 (talin 2 [Source:NCBI gene;Acc:100144637]) HSP 1 Score: 928.317 bits (2398), Expect = 0.000e+0 Identity = 681/2286 (29.79%), Postives = 1182/2286 (51.71%), Query Frame = 1
Query: 49 FELRIHIVDADVTKIVPLDPEATIFQLCETIRKNIREAQTKSPKSYGLYLPHDDLKKGLWLDNSKTLQHYILKRGDTIEYRNRSRWLHIRTMDGTNKTLKVDDSWTVSELMLTVCTKLGIYNYDEYSLISDKMDFSPGIDKTLSMKRGISINXXXXXXXXXXXXYHTEDGLNWLNPSQSLRQQGIEESEVLLLKRKYFFSDMNVDSRDPIQLSLLYEQLKDAVINGTHPVTLPEAIELAGLQCQVQLGNYSADKFKPGFLDLRECLPKEYQKNPKTVEKKIFNQHSKSKDLSEVEAKEKYCLLCRSFKTYGITFFLVKEKVIGKNKLIPRLLGVNKESVVQVDEKTKEIINTWPLTSIRKWAASFNGFTMDFGEYSPDEYYTAQTDKGERISQLIAGYIDIILKRKKAKDHLGVDADEESIMYEENIAPSKAIIVEHVPKQKRSSVSEEDVVIRKKAHMANSSVRMNSQASDSVCSQDCTDFYQEDINMSRQTSSLGRTQSPSSSLTTNSMHY-RMSDDDIRQKLYIISLQDNLDTIQKYKDQLMIENKGPEIGKDEASQQWIYVNIDNSRQRMADEIGAMNAAVAQVLRSAQGLATIXXXXXXXXXXXXIAKMQNSFSLITVHLPSLMEEIRTAAYYQDQLTDEDVSGEELIAAAKRLADAFTNLIKAAYPVEDQKRSLNRKEIFDAANAVGEASSDLLQQITEQENCQIELKSERPYSIIMITEEDQLYQEELLRLAKSVANETTNLIKQVKVIAVEAENPSDQKKVVMAATETGLAISQLISTTKIVAPTIEQSVCQEQLIFSIEDVSKAIQVVVESSNKATQSEELQDLTVQAANQVQEALDTLMKHLRXXXXXXXXXXXXXXAYENI----QEXXXXXXXXXXXXXXXRRLAQATTAMISEIQLKAVNEQYKTPEERDKLINAAKQLAEATTVLIDSAKNCTMDKDEMNLRYTLREATERFIVVTYTTECATYIQEQVIDHLLVAARKAATTGTHLINTSLSA--AKKSRASNFKVCNDGRELSNQISNLIVAIKEARRDPKDHLAQLELIAACRDYIDPSEQLSQSNKYMWPTVSDPSLQTALNQSINQSVIATEELKKCVHQADLMCQHLDLSAALEQLKRLEQNLKSIKNSIERENLIPLPDEKSDESAALLIKSVRRSGSAANQFKNDLESRCVVYEQTNGEDSYQNLENLDVAGQKARELSMALDRLVHAARGVAASIEFENQESENNDKNLEKLAQLQIVNNCLEAVKAARDLVIEAKS---SPPDNDQMDRAQQASVRXXXXXXXXXXXXPGQRDLDMLSKHIESKKHQFAENRLPIQQNNNINLSNCRSELTDTTFDFNQAVNELVSAPSFNLVNKGCKKMRMSYDRIVEICNVLVHDPFDESDSALHHLSSNRD---HIANGVMIMSEDCQTLLDKVKKIQCEPDNIIVRKQLQEATKMLLDSINRLLTNISTNLRPGQKECDKTIYRLESMRPILDNPVHPISHKDYFECLDFIIDKTVQPLADSLKNIPAAVKDENNQKFIDSIYHCADSVCMLLEETAQTAYLVGVGDVRSKIGNKGLADHTSFLQIQKEISENCQTICNPDTTARQDSSLMISTAGQIAENSRKLCEASK--TIMISFPNDKIKLSDKTKITLLAVSELMTGVQNLNQNFNEDNRKEVESLSGKVQDNVAELVQLLLSYKFAGDAAIISEEAKESQGPIKAAGITVLDTAIEVIQCSKALISSEANEELFIAYSSSCKDLNDALKHLISTIKESAPGQKECDEXXXXXXXXXXQAYDSKMKIMKHRSR----TISRTFE-----SEESYQNILQSALIQMPHCINELSRAGKKEPEQLARIFSRQTQLLESMVNSCICAANQTDLIQNSNIYLEHLITILEASEQLLKAVKKSGGNPKANSVHSQIDEMAQGVIESCEDLLAALDKISFKQGNVNTIVETITKSSAKVQESAIIPEKSRFGNSQSKMLDICYDMNNLTTDISSNANSESTQRLLAPLTQNLTQRYDDLCRACQGAVATLSNENNGKQLQECVQTVGKVSISLVK--STTEVRPSVASSISNLQAKTQELHKRIDDVIQLLISSNVGTQACTQAIKILKEINSDIDTSILFVKSADIQNDDREYYSVKELFKKSRNSVIDNSSELVRNIKLIVSKDVCDVNILQESADQIAITSQSLANDVKVGLEHLNSSTSQYNIELLVSFQEVIVSLISFLEVARNTSGLPYTDPLFQNLKEEGKCSINAITSLLKVLKSMDDVNLKDFQAIDNAI 6828
L+I + +V K + +P ++ C IR+ + EAQ+ +GL+L +D +KG+WL+ +TL +Y+L+ GD +EY+ + R IR +DG K + VDDS TV EL++T+C+++GI NY+EYSLI + M+ ++T ++K+ ++ +D++K++KLK K HTED LNWL+ S++ R+QG++E+E LLL+RK+F+SD NVDSRDP+QL+LLY Q +D ++NG+HPV+ +A E G+Q Q+Q G + K KPGFL+L+E LPKEY K + EKKIF +H +++E+EAK KY L RS +TYG++FFLVKEK+ GKNKL+PRLLG+ K+SV++VDEKTKE++ WPLT++++WAAS FT+DFGEY + YY+ QT +GE+ISQLIAGYIDIILK+K++KD G++ DEES M EE+++P K+ I++ ++ + K + ++ ++ S +T ++G S LTT MH M Q+ + ++ ++ +Q+ L + P +G D AS+ WI +D S+ + ++ A+ A A V+ G T + I+ S L +LME DE SGE+L+ AA+ LA A ++L+ A P + R+ + AA ++G+AS +LL+QI E E D+ +Q+ L+ LAK+VAN L+ + K +A E+ Q +V+ AAT+ L+ SQL++ K+V+PTI VCQEQLI + + V ++++ V + + AT+ EL AA+ V +AL+ L++H+R+ + + + + A + I + + S D ++V AR LAQAT+ +++ ++ A E + KL+ AAK LA++T ++++AK + + + + LREA E V T I++++++ L AA++AA T I S +A + K+ A++ ++ + +++ I L+ ++ ++ +D AQL LI + ++++ P ++ S K PTV+D + L+Q + EL+ +A C +++ +AL ++ L+ L+ K + L PLP E ++ A L + + GS+ Q C G + Y G ARE + AL L AARGVAAS S+ ++++ + ++ + +L+ EAK +P D + R Q + +S +L+ C++ LPGQ+D+DM K I + + LP + + +SEL D NQ+ E+V A + S D D F ++ + + N+D + + +S LL K + + + L A + + +SIN+L+T + T PGQKECD + LE+++ +L+NP P S YF+C++ +++ + + L +S+ I K + F + + + ++C L E Q AYLVG+ D S+ G +GL D F + + I CQ + +P ++ Q ++S A +A+++ LC A + + + P K K + + L+ ++ L+ +F+E+NR + + + V L + +FA A IS E +Q PI + +T+L+++ +I+ +++L + + + + + + ++D++K LI++I++ APGQ+ECD Q+ DS + ++ + ++S+ S E+ Q L S + ++ H I+ ++ A + E QL ++ + E +V + + ++ Q L+ T+ E++ Q+L A K+ GGNPKA H I E AQ + E+ +DL+ L++ + + G V +V++I ++ +K+ E F + Q+ + Y T S + L L +T Y +L + A AT + G Q++ +Q +G I LV+ ++ P+ + + L + + +++ V+ L + N GTQAC A + I +D+DT+I+F + + ++ KE F R +++ + LV + KL+VS L ++A A T LA VK+G L S + + L+ + ++V +L +E + +G DP LK K + +TSLLK +K+++D + +A++ I
Sbjct: 4 LSLKICVRQCNVVKTMQFEPSTAVYDACRIIRERVSEAQSGQALDFGLFLSDEDPRKGIWLEAGRTLDYYMLRNGDVLEYKKKHRPQKIRMLDGAAKMILVDDSKTVGELLVTICSRIGITNYEEYSLIRETME-EKKEEQTGTLKKDRTLLRDEKKMEKLKAKLHTEDELNWLDHSRTFREQGVDENETLLLRRKFFYSDQNVDSRDPVQLNLLYVQARDDILNGSHPVSFDKACEFGGIQAQIQFGPHVESKHKPGFLELKEFLPKEYMKQ-RGAEKKIFQEHKNCGEMTEIEAKVKYVKLARSLRTYGVSFFLVKEKMKGKNKLVPRLLGITKDSVMRVDEKTKEVLQEWPLTTVKRWAASPKSFTLDFGEYQ-ESYYSVQTTEGEQISQLIAGYIDIILKKKQSKDRFGLEGDEESTMLEESVSPKKSTILQ-----------QQQITRPGKPELGTVALPAIIRSGSS----------------GPETFNVGSMPSAQQQLTTGQMHRGHMPPLTSAQQALMGTINTSMHAVQQAHSDLSQVDNLPPLGHDMASRVWIQNKVDESKHEIHSQVDAITAGTASVVNLTAGDPTETDYTAVGCAITTISSNLTEMSKGVKLLAALME-------------DEVGSGEKLLGAARTLAGAVSDLLTAVQPSSGEP----RQTVLTAAGSIGQASGELLRQIGE-------------------NEADERFQDVLMNLAKAVANAAAMLVLKAKNVAQVTEDTVLQNRVIAAATQCALSTSQLVACAKVVSPTISSPVCQEQLIEAGKLVDRSVENCVHACHSATEDIELLKQVSAAASVVSQALNDLLQHVRQFASRGEPIGRYDQATDTIMSVTESIFSSMGDAGEMVRQARVLAQATSDLVNAMRSDA--EAEIDMDNSKKLLAAAKLLADSTARMVEAAKGAAANPENEDQQQRLREAAEGLRVAT-NAAAQNAIKKKIVNRLEAAAKQAAAAATQTIAASQNASLSNKNTAAHQQLVQSCKTVADHIPQLVQGVRSSQAQAEDLSAQLTLIVSSQNFLQPGSKMVASAKAAVPTVTDQAAAMQLSQCAKNLATSLAELRTAAQKAHEACGPMEIDSALNAVQTLKNELQDAKMAASDRQLKPLPGETLEKCAQDLGSTSKTVGSSMAQLLT-----CAA----QGNEHY--------TGVAARETAQALKTLAQAARGVAASTSDPQAASD-------------MLDSARDVMEGSANLIQEAKQALVAPGDAEIQQRLAQVAKAVSHSLNNCVNCLPGQKDVDMALKSIGESSKKLLVDSLP---PSTKSFQEAQSELNQAAEDLNQSAGEVVHASRGQSGELAAASGKFSQD----------FDEFLDAGIEMAGQTQNKDDQMQVIGSLKTISMASSKLLLAAKSLSVDSGAPSAKNLLAAAARAVTESINQLIT-LCTQQAPGQKECDNALRELETVKGMLENPNEPASDLSYFDCIESVMENS-KVLGESMAGISQNAKTGDLPAFGECVSVASKALCGLTEAAVQAAYLVGISDPNSQAGQQGLVDPIQFARANQAIQMACQNLVDPASSPSQ----VLSAATIVAKHTSALCNACRIASSKTANPVAKRHFVQSAKEVANSTANLVKTIKTLDGDFSEENRNKCSIATSPLISAVENLTAFASNPEFASIPAQISSEGARAQEPILVSAVTMLESSSSLIKTARSLAINPKDPPTWSSLAGHSRIVSDSIKSLITSIRDKAPGQRECD-----------QSIDSINRFIRDIEQASLASVSQDLAMRDDISLEALQEQLTSVVQEIGHLIDPITTAARGEAAQLGHKVTQLARYFEPLVLAAVGLVSKVLDHQQQMTVLDQTKTLAESALQMLYAAKEGGGNPKAFHTHDAIAEAAQLMKEAVDDLMITLNEAASEVGMVGGMVDSIAEAMSKLDEGTPPEPTGTFVDYQTT--GVKYSKAIAVTAQEMMTKSVTNPEELGGLASQVTSDYGNLAVQGRMAAATAEPKEVGFQIKSRIQDLGHGCIFLVQKAGALQICPTDSYTKRELIECARAVTEKVSLVLSALQAGNKGTQACITASSAVSGIIADLDTTIMFATAGTLNAEN------KESFADHRENILKTAKALVEDTKLLVSGAASSQEKLAQAAQSSANTITQLAEVVKLGAASLGSDDPETQVVLINAIKDVAKALGDLIEATKCAAGKAADDPSMYQLKSAAKVMVTNVTSLLKTVKAVEDEATRGTRALEATI 2152
BLAST of Talin-1 vs. Ensembl Xenopus
Match: TLN2 (talin 2 [Source:NCBI gene;Acc:100144637]) HSP 1 Score: 924.08 bits (2387), Expect = 0.000e+0 Identity = 711/2453 (28.98%), Postives = 1244/2453 (50.71%), Query Frame = 1
Query: 49 FELRIHIVDADVTKIVPLDPEATIFQLCETIRKNIREAQTKSPKSYGLYLPHDDLKKGLWLDNSKTLQHYILKRGDTIEYRNRSRWLHIRTMDGTNKTLKVDDSWTVSELMLTVCTKLGIYNYDEYSLISDKMDFSPGIDKTLSMKRGISINXXXXXXXXXXXXYHTEDGLNWLNPSQSLRQQGIEESEVLLLKRKYFFSDMNVDSRDPIQLSLLYEQLKDAVINGTHPVTLPEAIELAGLQCQVQLGNYSADKFKPGFLDLRECLPKEYQKNPKTVEKKIFNQHSKSKDLSEVEAKEKYCLLCRSFKTYGITFFLVKEKVIGKNKLIPRLLGVNKESVVQVDEKTKEIINTWPLTSIRKWAASFNGFTMDFGEYSPDEYYTAQTDKGERISQLIAGYIDIILKRKKAKDHLGVDADEESIMYEENIAPSKAIIVEHVPKQKRSSVSEEDVVIRKKAHMANSSVRMNSQASDSVCSQDCTDFYQEDINMSRQTSSLGRTQSPSSSLTTNSMHY-RMSDDDIRQKLYIISLQDNLDTIQKYKDQLMIENKGPEIGKDEASQQWIYVNIDNSRQRMADEIGAMNAAVAQVLRSAQGLATIXXXXXXXXXXXXIAKMQNSFSLITVHLPSLMEEIRTAAYYQDQLTDEDVSGEELIAAAKRLADAFTNLIKAAYPVEDQKRSLNRKEIFDAANAVGEASSDLLQQITEQENCQIELKSERPYSIIMITEEDQLYQ--EELLRLAKSVANETTNLIKQVKVIAVEAENPSDQKKVVMAATETGLAISQLISTTKIVAPTIEQSVCQEQLIFSIEDVSKAIQVVVESSNKATQSEELQDLTVQAANQVQEALDTLMKHLRXXXXXXXXXXXXXXAYENI----QEXXXXXXXXXXXXXXXRRLAQATTAMISEIQLKAVNEQYKTPEERDKLINAAKQLAEATTVLIDSAKNCTMDKDEMNLRYTLREATERFIVVTYTTECATYIQEQVIDHLLVAARKAATTGTHLINTSLSA--AKKSRASNFKVCNDGRELSNQISNLIVAIKEARRDPKDHLAQLELIAACRDYIDPSEQLSQSNKYMWPTVSDPSLQTALNQSINQSVIATEELKKCVHQADLMCQHLDLSAALEQLKRLEQNLKSIKNSIERENLIPLPDEKSDESAALLIKSVRRSGSAANQFKNDLESRCVVYEQTNGEDSYQNLENLDVAGQKARELSMALDRLVHAARGVAASIEFENQESENNDKNLEKLAQLQIVNNCLEAVKAARDLVIEAKS---SPPDNDQMDRAQQASVRXXXXXXXXXXXXPGQRDLDMLSKHIESKKHQFAENRLPIQQNNNINLSNCRSELTDTTFDFNQAVNELVSAPSFNLVNKGCKKMRMSYDRIVEICNVLVHDPFDESDSALHHLSSNRD---HIANGVMIMSEDCQTLLDKVKKIQCEPDNIIVRKQLQEATKMLLDSINRLLTNISTNLRPGQKECDKTIYRLESMRPILDNPVHPISHKDYFECLDFIIDKTVQPLADSLKNIPAAVKDENNQKFIDSIYHCADSVCMLLEETAQTAYLVGVGDVRSKIGNKGLADHTSFLQIQKEISENCQTICNPDTTARQDSSLMISTAGQIAENSRKLCEASK--TIMISFPNDKIKLSDKTKITLLAVSELMTGVQNLNQNFNEDNRKEVESLSGKVQDNVAELVQLLLSYKFAGDAAIISEEAKESQGPIKAAGITVLDTAIEVIQCSKALISSEANEELFIAYSSSCKDLNDALKHLISTIKESAPGQKECDEXXXXXXXXXXQAYDSKMKIMKHRSR----TISRTFE-----SEESYQNILQSALIQMPHCINELSRAGKKEPEQLARIFSRQTQLLESMVNSCICAANQTDLIQNSNIYLEHLITILEASEQLLKAVKKSGGNPKANSVHSQIDEMAQGVIESCEDLLAALDKISFKQGNVNTIVETITKSSAKVQESAIIPEKSRFGNSQSKMLDICYDMNNLTTDISSNANSESTQRLLAPLTQNLTQRYDDLCRACQGAVATLSNENNGKQLQECVQTVGKVSISLVK--STTEVRPSVASSISNLQAKTQELHKRIDDVIQLLISSNVGTQACTQAIKILKEINSDIDTSILFVKSADIQNDDREYYSVKELFKKSRNSVIDNSSELVRNIKLIVSKDVCDVNILQESADQIAITSQSLANDVKVGLEHLNSSTSQYNIELLVSFQEVIVSLISFLEVARNTSGLPYTDPLFQNLKEEGKCSINAITSLLKVLKSMDDVNLKDFQAIDNAIIXXXXXXXXXXXXXXGISREASPVESPTSTNRLSIGSDITVSPRFAPEEINRLIPSLANVCDKILEISSPEFKPIIRQENISVVSISCSKVNNELTSACKNLLRNGPV-TDSKKQTLNTVDQLVENYTELLKNFKLYLTNPTKETR----IPVETVVSKLNELIK 7308
L+I + +V K + +P ++ C IR+ + EAQ+ +GL+L +D +KG+WL+ +TL +Y+L+ GD +EY+ + R IR +DG K + VDDS TV EL++T+C+++GI NY+EYSLI + M+ ++T ++K+ ++ +D++K++KLK K HTED LNWL+ S++ R+QG++E+E LLL+RK+F+SD NVDSRDP+QL+LLY Q +D ++NG+HPV+ +A E G+Q Q+Q G + K KPGFL+L+E LPKEY K + EKKIF +H +++E+EAK KY L RS +TYG++FFLVKEK+ GKNKL+PRLLG+ K+SV++VDEKTKE++ WPLT++++WAAS FT+DFGEY + YY+ QT +GE+ISQLIAGYIDIILK+K++KD G++ DEES M EE+++P K+ I++ ++ + K + ++ ++ S +T ++G S LTT MH M Q+ + ++ ++ +Q+ L + P +G D AS+ WI +D S+ + ++ A+ A A V+ G T + I+ S L +LME DE SGE+L+ AA+ LA A ++L+ A P + R+ + AA ++G+AS +LL+QI E E D+ +Q + L+ LAK+VAN L+ + K +A E+ Q +V+ AAT+ L+ SQL++ K+V+PTI VCQEQLI + + V ++++ V + + AT+ EL AA+ V +AL+ L++H+R+ + + + + A + I + + S D ++V AR LAQAT+ +++ ++ A E + KL+ AAK LA++T ++++AK + + + + LREA E V T I++++++ L AA++AA T I S +A + K+ A++ ++ + +++ I L+ ++ ++ +D AQL LI + ++++ P ++ S K PTV+D + L+Q + EL+ +A C +++ +AL ++ L+ L+ K + L PLP E ++ A L + + GS+ Q C G + Y G ARE + AL L AARGVAAS S+ ++++ + ++ + +L+ EAK +P D + R Q + +S +L+ C++ LPGQ+D+DM K I + + LP + + +SEL D NQ+ E+V A + S D D F ++ + + N+D + + +S LL K + + + L A + + +SIN+L+T + T PGQKECD + LE+++ +L+NP P S YF+C++ +++ + + L +S+ I K + F + + + ++C L E Q AYLVG+ D S+ G +GL D F + + I CQ + +P ++ Q ++S A +A+++ LC A + + + P K K + + L+ ++ L+ +F+E+NR + + + V L + +FA A IS E +Q PI + +T+L+++ +I+ +++L + + + + + + ++D++K LI++I++ APGQ+ECD Q+ DS + ++ + ++S+ S E+ Q L S + ++ H I+ ++ A + E QL ++ + E +V + + ++ Q L+ T+ E++ Q+L A K+ GGNPKA H I E AQ + E+ +DL+ L++ + + G V +V++I ++ +K+ E F + Q+ + Y T S + L L +T Y +L + A AT + G Q++ +Q +G I LV+ ++ P+ + + L + + +++ V+ L + N GTQAC A + I +D+DT+I+F + + ++ KE F R +++ + LV + KL+VS L ++A A T LA VK+G L S + + L+ + ++V +L +E + +G DP LK K + +TSLLK +K+++D + +A++ I I +E + +S + S +PEE R+ + K + + RQE++ + K +E+ +ACK + + V D++++ + Y E+L++ L P+ ET+ I + + + + ELI+
Sbjct: 4 LSLKICVRQCNVVKTMQFEPSTAVYDACRIIRERVSEAQSGQALDFGLFLSDEDPRKGIWLEAGRTLDYYMLRNGDVLEYKKKHRPQKIRMLDGAAKMILVDDSKTVGELLVTICSRIGITNYEEYSLIRETME-EKKEEQTGTLKKDRTLLRDEKKMEKLKAKLHTEDELNWLDHSRTFREQGVDENETLLLRRKFFYSDQNVDSRDPVQLNLLYVQARDDILNGSHPVSFDKACEFGGIQAQIQFGPHVESKHKPGFLELKEFLPKEYMKQ-RGAEKKIFQEHKNCGEMTEIEAKVKYVKLARSLRTYGVSFFLVKEKMKGKNKLVPRLLGITKDSVMRVDEKTKEVLQEWPLTTVKRWAASPKSFTLDFGEYQ-ESYYSVQTTEGEQISQLIAGYIDIILKKKQSKDRFGLEGDEESTMLEESVSPKKSTILQ-----------QQQITRPGKPELGTVALPAIIRSGSS----------------GPETFNVGSMPSAQQQLTTGQMHRGHMPPLTSAQQALMGTINTSMHAVQQAHSDLSQVDNLPPLGHDMASRVWIQNKVDESKHEIHSQVDAITAGTASVVNLTAGDPTETDYTAVGCAITTISSNLTEMSKGVKLLAALME-------------DEVGSGEKLLGAARTLAGAVSDLLTAVQPSSGEP----RQTVLTAAGSIGQASGELLRQIGE-------------------NEADERFQVFDVLMNLAKAVANAAAMLVLKAKNVAQVTEDTVLQNRVIAAATQCALSTSQLVACAKVVSPTISSPVCQEQLIEAGKLVDRSVENCVHACHSATEDIELLKQVSAAASVVSQALNDLLQHVRQFASRGEPIGRYDQATDTIMSVTESIFSSMGDAGEMVRQARVLAQATSDLVNAMRSDA--EAEIDMDNSKKLLAAAKLLADSTARMVEAAKGAAANPENEDQQQRLREAAEGLRVAT-NAAAQNAIKKKIVNRLEAAAKQAAAAATQTIAASQNASLSNKNTAAHQQLVQSCKTVADHIPQLVQGVRSSQAQAEDLSAQLTLIVSSQNFLQPGSKMVASAKAAVPTVTDQAAAMQLSQCAKNLATSLAELRTAAQKAHEACGPMEIDSALNAVQTLKNELQDAKMAASDRQLKPLPGETLEKCAQDLGSTSKTVGSSMAQLLT-----CAA----QGNEHY--------TGVAARETAQALKTLAQAARGVAASTSDPQAASD-------------MLDSARDVMEGSANLIQEAKQALVAPGDAEIQQRLAQVAKAVSHSLNNCVNCLPGQKDVDMALKSIGESSKKLLVDSLP---PSTKSFQEAQSELNQAAEDLNQSAGEVVHASRGQSGELAAASGKFSQD----------FDEFLDAGIEMAGQTQNKDDQMQVIGSLKTISMASSKLLLAAKSLSVDSGAPSAKNLLAAAARAVTESINQLIT-LCTQQAPGQKECDNALRELETVKGMLENPNEPASDLSYFDCIESVMENS-KVLGESMAGISQNAKTGDLPAFGECVSVASKALCGLTEAAVQAAYLVGISDPNSQAGQQGLVDPIQFARANQAIQMACQNLVDPASSPSQ----VLSAATIVAKHTSALCNACRIASSKTANPVAKRHFVQSAKEVANSTANLVKTIKTLDGDFSEENRNKCSIATSPLISAVENLTAFASNPEFASIPAQISSEGARAQEPILVSAVTMLESSSSLIKTARSLAINPKDPPTWSSLAGHSRIVSDSIKSLITSIRDKAPGQRECD-----------QSIDSINRFIRDIEQASLASVSQDLAMRDDISLEALQEQLTSVVQEIGHLIDPITTAARGEAAQLGHKVTQLARYFEPLVLAAVGLVSKVLDHQQQMTVLDQTKTLAESALQMLYAAKEGGGNPKAFHTHDAIAEAAQLMKEAVDDLMITLNEAASEVGMVGGMVDSIAEAMSKLDEGTPPEPTGTFVDYQTT--GVKYSKAIAVTAQEMMTKSVTNPEELGGLASQVTSDYGNLAVQGRMAAATAEPKEVGFQIKSRIQDLGHGCIFLVQKAGALQICPTDSYTKRELIECARAVTEKVSLVLSALQAGNKGTQACITASSAVSGIIADLDTTIMFATAGTLNAEN------KESFADHRENILKTAKALVEDTKLLVSGAASSQEKLAQAAQSSANTITQLAEVVKLGAASLGSDDPETQVVLINAIKDVAKALGDLIEATKCAAGKAADDPSMYQLKSAAKVMVTNVTSLLKTVKAVEDEATRGTRALEATI--------------EHIKQELTVFQSKDIPEKTS-----------SPEESIRMTKGITTATAKAVAAGNS-----CRQEDVIATANLSRKAVSEMLTACKQAVYHPDVNADTRQRAFRYGTECTFAYLEMLEHVLSILQKPSLETKQQLSIFSKRIAAAVTELIQ 2289
BLAST of Talin-1 vs. Ensembl Xenopus
Match: TLN2 (talin 2 [Source:NCBI gene;Acc:100144637]) HSP 1 Score: 914.45 bits (2362), Expect = 0.000e+0 Identity = 706/2451 (28.80%), Postives = 1236/2451 (50.43%), Query Frame = 1
Query: 49 FELRIHIVDADVTKIVPLDPEATIFQLCETIRKNIREAQTKSPKSYGLYLPHDDLKKGLWLDNSKTLQHYILKRGDTIEYRNRSRWLHIRTMDGTNKTLKVDDSWTVSELMLTVCTKLGIYNYDEYSLISDKMDFSPGIDKTLSMKRGISINXXXXXXXXXXXXYHTEDGLNWLNPSQSLRQQGIEESEVLLLKRKYFFSDMNVDSRDPIQLSLLYEQLKDAVINGTHPVTLPEAIELAGLQCQVQLGNYSADKFKPGFLDLRECLPKEYQKNPKTVEKKIFNQHSKSKDLSEVEAKEKYCLLCRSFKTYGITFFLVKEKVIGKNKLIPRLLGVNKESVVQVDEKTKEIINTWPLTSIRKWAASFNGFTMDFGEYSPDEYYTAQTDKGERISQLIAGYIDIILKRKKAKDHLGVDADEESIMYEENIAPSKAIIVEHVPKQKRSSVSEEDVVIRKKAHMANSSVRMNSQASDSVCSQDCTDFYQEDINMSRQTSSLGRTQSPSSSLTTNSMHY-RMSDDDIRQKLYIISLQDNLDTIQKYKDQLMIENKGPEIGKDEASQQWIYVNIDNSRQRMADEIGAMNAAVAQVLRSAQGLATIXXXXXXXXXXXXIAKMQNSFSLITVHLPSLMEEIRTAAYYQDQLTDEDVSGEELIAAAKRLADAFTNLIKAAYPVEDQKRSLNRKEIFDAANAVGEASSDLLQQITEQENCQIELKSERPYSIIMITEEDQLYQEELLRLAKSVANETTNLIKQVKVIAVEAENPSDQKKVVMAATETGLAISQLISTTKIVAPTIEQSVCQEQLIFSIEDVSKAIQVVVESSNKATQSEELQDLTVQAANQVQEALDTLMKHLRXXXXXXXXXXXXXXAYENI----QEXXXXXXXXXXXXXXXRRLAQATTAMISEIQLKAVNEQYKTPEERDKLINAAKQLAEATTVLIDSAKNCTMDKDEMNLRYTLREATERFIVVTYTTECATYIQEQVIDHLLVAARKAATTGTHLINTSLSA--AKKSRASNFKVCNDGRELSNQISNLIVAIKEARRDPKDHLAQLELIAACRDYIDPSEQLSQSNKYMWPTVSDPSLQTALNQSINQSVIATEELKKCVHQADLMCQHLDLSAALEQLKRLEQNLKSIKNSIERENLIPLPDEKSDESAALLIKSVRRSGSAANQFKNDLESRCVVYEQTNGEDSYQNLENLDVAGQKARELSMALDRLVHAARGVAASIEFENQESENNDKNLEKLAQLQIVNNCLEAVKAARDLVIEAKS---SPPDNDQMDRAQQASVRXXXXXXXXXXXXPGQRDLDMLSKHIESKKHQFAENRLPIQQNNNINLSNCRSELTDTTFDFNQAVNELVSAPSFNLVNKGCKKMRMSYDRIVEICNVLVHDPFDESDSALHHLSSNRD---HIANGVMIMSEDCQTLLDKVKKIQCEPDNIIVRKQLQEATKMLLDSINRLLTNISTNLRPGQKECDKTIYRLESMRPILDNPVHPISHKDYFECLDFIIDKTVQPLADSLKNIPAAVKDENNQKFIDSIYHCADSVCMLLEETAQTAYLVGVGDVRSKIGNKGLADHTSFLQIQKEISENCQTICNPDTTARQDSSLMISTAGQIAENSRKLCEASK--TIMISFPNDKIKLSDKTKITLLAVSELMTGVQNLNQNFNEDNRKEVESLSGKVQDNVAELVQLLLSYKFAGDAAIISEEAKESQGPIKAAGITVLDTAIEVIQCSKALISSEANEELFIAYSSSCKDLNDALKHLISTIKESAPGQKECDEXXXXXXXXXXQAYDSKMKIMKHRSR----TISRTFE-----SEESYQNILQSALIQMPHCINELSRAGKKEPEQLARIFSRQTQLLESMVNSCICAANQTDLIQNSNIYLEHLITILEASEQLLKAVKKSGGNPKANSVHSQIDEMAQGVIESCEDLLAALDKISFKQGNVNTIVETITKSSAKVQESAIIPEKSRFGNSQSKMLDICYDMNNLTTDISSNANSESTQRLLAPLTQNLTQRYDDLCRACQGAVATLSNENNGKQLQECVQTVGKVSISLVK--STTEVRPSVASSISNLQAKTQELHKRIDDVIQLLISSNVGTQACTQAIKILKEINSDIDTSILFVKSADIQNDDREYYSVKELFKKSRNSVIDNSSELVRNIKLIVSKDVCDVNILQESADQIAITSQSLANDVKVGLEHLNSSTSQYNIELLVSFQEVIVSLISFLEVARNTSGLPYTDPLFQNLKEEGKCSINAITSLLKVLKSMDDVNLKDFQAIDNAIIXXXXXXXXXXXXXXGISREASPVESPTSTNRLSIGSDITVSPRFAPEEINRLIPSLANVCDKILEISSPEFKPIIRQENISVVSISCSKVNNELTSACKNLLRNGPV-TDSKKQTLNTVDQLVENYTELLKNFKLYLTNPTKETR----IPVETVVSKLNELIK 7308
L+I + +V K + +P ++ C IR+ + EAQ+ +GL+L +D +KG+WL+ +TL +Y+L+ GD +EY+ + R IR +DG K + VDDS TV EL++T+C+++GI NY+EYSLI + M+ ++T ++K+ ++ +D++K++KLK K HTED LNWL+ S++ R+QG++E+E LLL+RK+F+SD NVDSRDP+QL+LLY Q +D ++NG+HPV+ +A E G+Q Q+Q G + K KPGFL+L+E LPKEY K + EKKIF +H +++E+EAK KY L RS +TYG++FFLVKEK+ GKNKL+PRLLG+ K+SV++VDEKTKE++ WPLT++++WAAS FT+DFGEY + YY+ QT +GE+ISQLIAGYIDIILK+K++KD G++ DEES M EE+++P K+ I++ ++ + K + ++ ++ S +T ++G S LTT MH M Q+ + ++ ++ +Q+ L + P +G D AS+ WI +D S+ + ++ A+ A A V+ G T + I+ S L +LME DE SGE+L+ AA+ LA A ++L+ A P + R+ + AA ++G+AS +LL+QI E E D+ +Q+ L+ LAK+VAN L+ + K +A E+ Q +V+ AAT+ L+ SQL++ K+V+PTI VCQEQLI + + V ++++ V + + AT+ EL AA+ V +AL+ L++H+R+ + + + + A + I + + S D ++V AR LAQAT+ +++ ++ A E + KL+ AAK LA++T ++++AK + + + + LREA E V T I++++++ L AA++AA T I S +A + K+ A++ ++ + +++ I L+ ++ ++ +D AQL LI + ++++ P ++ S K PTV+D + L+Q + EL+ +A C +++ +AL ++ L+ L+ K + L PLP E ++ A L + + GS+ Q C G + Y G ARE + AL L AARGVAAS S+ ++++ + ++ + +L+ EAK +P D + R Q + +S +L+ C++ LPGQ+D+DM K I + + LP + + +SEL D NQ+ E+V A + S D D F ++ + + N+D + + +S LL K + + + L A + + +SIN+L+T + T PGQKECD + LE+++ +L+NP P S YF+C++ +++ + + L +S+ I K + F + + + ++C L E Q AYLVG+ D S+ G +GL D F + + I CQ + +P ++ Q ++S A +A+++ LC A + + + P K K + + L+ ++ L+ +F+E+NR + + + V L + +FA A IS E +Q PI + +T+L+++ +I+ +++L + + + + + + ++D++K LI++I++ APGQ+ECD Q+ DS + ++ + ++S+ S E+ Q L S + ++ H I+ ++ A + E QL ++ + E +V + + ++ Q L+ T+ E++ Q+L A K+ GGNPKA H I E AQ + E+ +DL+ L++ + + G V +V++I ++ +K+ E F + Q TT + +Y A+A + E G Q++ +Q +G I LV+ ++ P+ + + L + + +++ V+ L + N GTQAC A + I +D+DT+I+F + + ++ KE F R +++ + LV + KL+VS L ++A A T LA VK+G L S + + L+ + ++V +L +E + +G DP LK K + +TSLLK +K+++D + +A++ I I +E + +S + S +PEE R+ + K + + RQE++ + K +E+ +ACK + + V D++++ + Y E+L++ L P+ ET+ I + + + + ELI+
Sbjct: 4 LSLKICVRQCNVVKTMQFEPSTAVYDACRIIRERVSEAQSGQALDFGLFLSDEDPRKGIWLEAGRTLDYYMLRNGDVLEYKKKHRPQKIRMLDGAAKMILVDDSKTVGELLVTICSRIGITNYEEYSLIRETME-EKKEEQTGTLKKDRTLLRDEKKMEKLKAKLHTEDELNWLDHSRTFREQGVDENETLLLRRKFFYSDQNVDSRDPVQLNLLYVQARDDILNGSHPVSFDKACEFGGIQAQIQFGPHVESKHKPGFLELKEFLPKEYMKQ-RGAEKKIFQEHKNCGEMTEIEAKVKYVKLARSLRTYGVSFFLVKEKMKGKNKLVPRLLGITKDSVMRVDEKTKEVLQEWPLTTVKRWAASPKSFTLDFGEYQ-ESYYSVQTTEGEQISQLIAGYIDIILKKKQSKDRFGLEGDEESTMLEESVSPKKSTILQ-----------QQQITRPGKPELGTVALPAIIRSGSS----------------GPETFNVGSMPSAQQQLTTGQMHRGHMPPLTSAQQALMGTINTSMHAVQQAHSDLSQVDNLPPLGHDMASRVWIQNKVDESKHEIHSQVDAITAGTASVVNLTAGDPTETDYTAVGCAITTISSNLTEMSKGVKLLAALME-------------DEVGSGEKLLGAARTLAGAVSDLLTAVQPSSGEP----RQTVLTAAGSIGQASGELLRQIGE-------------------NEADERFQDVLMNLAKAVANAAAMLVLKAKNVAQVTEDTVLQNRVIAAATQCALSTSQLVACAKVVSPTISSPVCQEQLIEAGKLVDRSVENCVHACHSATEDIELLKQVSAAASVVSQALNDLLQHVRQFASRGEPIGRYDQATDTIMSVTESIFSSMGDAGEMVRQARVLAQATSDLVNAMRSDA--EAEIDMDNSKKLLAAAKLLADSTARMVEAAKGAAANPENEDQQQRLREAAEGLRVAT-NAAAQNAIKKKIVNRLEAAAKQAAAAATQTIAASQNASLSNKNTAAHQQLVQSCKTVADHIPQLVQGVRSSQAQAEDLSAQLTLIVSSQNFLQPGSKMVASAKAAVPTVTDQAAAMQLSQCAKNLATSLAELRTAAQKAHEACGPMEIDSALNAVQTLKNELQDAKMAASDRQLKPLPGETLEKCAQDLGSTSKTVGSSMAQLLT-----CAA----QGNEHY--------TGVAARETAQALKTLAQAARGVAASTSDPQAASD-------------MLDSARDVMEGSANLIQEAKQALVAPGDAEIQQRLAQVAKAVSHSLNNCVNCLPGQKDVDMALKSIGESSKKLLVDSLP---PSTKSFQEAQSELNQAAEDLNQSAGEVVHASRGQSGELAAASGKFSQD----------FDEFLDAGIEMAGQTQNKDDQMQVIGSLKTISMASSKLLLAAKSLSVDSGAPSAKNLLAAAARAVTESINQLIT-LCTQQAPGQKECDNALRELETVKGMLENPNEPASDLSYFDCIESVMENS-KVLGESMAGISQNAKTGDLPAFGECVSVASKALCGLTEAAVQAAYLVGISDPNSQAGQQGLVDPIQFARANQAIQMACQNLVDPASSPSQ----VLSAATIVAKHTSALCNACRIASSKTANPVAKRHFVQSAKEVANSTANLVKTIKTLDGDFSEENRNKCSIATSPLISAVENLTAFASNPEFASIPAQISSEGARAQEPILVSAVTMLESSSSLIKTARSLAINPKDPPTWSSLAGHSRIVSDSIKSLITSIRDKAPGQRECD-----------QSIDSINRFIRDIEQASLASVSQDLAMRDDISLEALQEQLTSVVQEIGHLIDPITTAARGEAAQLGHKVTQLARYFEPLVLAAVGLVSKVLDHQQQMTVLDQTKTLAESALQMLYAAKEGGGNPKAFHTHDAIAEAAQLMKEAVDDLMITLNEAASEVGMVGGMVDSIAEAMSKLDEGTPPEPTGTFVDYQ-------------TTGV----------------------KYSK-------AIAVTAQEMVGFQIKSRIQDLGHGCIFLVQKAGALQICPTDSYTKRELIECARAVTEKVSLVLSALQAGNKGTQACITASSAVSGIIADLDTTIMFATAGTLNAEN------KESFADHRENILKTAKALVEDTKLLVSGAASSQEKLAQAAQSSANTITQLAEVVKLGAASLGSDDPETQVVLINAIKDVAKALGDLIEATKCAAGKAADDPSMYQLKSAAKVMVTNVTSLLKTVKAVEDEATRGTRALEATI--------------EHIKQELTVFQSKDIPEKTS-----------SPEESIRMTKGITTATAKAVAAGNS-----CRQEDVIATANLSRKAVSEMLTACKQAVYHPDVNADTRQRAFRYGTECTFAYLEMLEHVLSILQKPSLETKQQLSIFSKRIAAAVTELIQ 2247
BLAST of Talin-1 vs. Ensembl Xenopus
Match: TLN2 (talin 2 [Source:NCBI gene;Acc:100144637]) HSP 1 Score: 913.679 bits (2360), Expect = 0.000e+0 Identity = 707/2444 (28.93%), Postives = 1235/2444 (50.53%), Query Frame = 1
Query: 49 FELRIHIVDADVTKIVPLDPEATIFQLCETIRKNIREAQTKSPKSYGLYLPHDDLKKGLWLDNSKTLQHYILKRGDTIEYRNRSRWLHIRTMDGTNKTLKVDDSWTVSELMLTVCTKLGIYNYDEYSLISDKMDFSPGIDKTLSMKRGISINXXXXXXXXXXXXYHTEDGLNWLNPSQSLRQQGIEESEVLLLKRKYFFSDMNVDSRDPIQLSLLYEQLKDAVINGTHPVTLPEAIELAGLQCQVQLGNYSADKFKPGFLDLRECLPKEYQKNPKTVEKKIFNQHSKSKDLSEVEAKEKYCLLCRSFKTYGITFFLVKEKVIGKNKLIPRLLGVNKESVVQVDEKTKEIINTWPLTSIRKWAASFNGFTMDFGEYSPDEYYTAQTDKGERISQLIAGYIDIILKRKKAKDHLGVDADEESIMYEENIAPSKAIIVEHVPKQKRSSVSEEDVVIRKKAHMANSSVRMNSQASDSVCSQDCTDFYQEDINMSRQTSSLGRTQSPSSSLTTNSMHY-RMSDDDIRQKLYIISLQDNLDTIQKYKDQLMIENKGPEIGKDEASQQWIYVNIDNSRQRMADEIGAMNAAVAQVLRSAQGLATIXXXXXXXXXXXXIAKMQNSFSLITVHLPSLMEEIRTAAYYQDQLTDEDVSGEELIAAAKRLADAFTNLIKAAYPVEDQKRSLNRKEIFDAANAVGEASSDLLQQITEQENCQIELKSERPYSIIMITEEDQLYQEELLRLAKSVANETTNLIKQVKVIAVEAENPSDQKKVVMAATETGLAISQLISTTKIVAPTIEQSVCQEQLIFSIEDVSKAIQVVVESSNKATQSEELQDLTVQAANQVQEALDTLMKHLRXXXXXXXXXXXXXXAYENI----QEXXXXXXXXXXXXXXXRRLAQATTAMISEIQLKAVNEQYKTPEERDKLINAAKQLAEATTVLIDSAKNCTMDKDEMNLRYTLREATERFIVVTYTTECATYIQEQVIDHLLVAARKAATTGTHLINTSLSA--AKKSRASNFKVCNDGRELSNQISNLIVAIKEARRDPKDHLAQLELIAACRDYIDPSEQLSQSNKYMWPTVSDPSLQTALNQSINQSVIATEELKKCVHQADLMCQHLDLSAALEQLKRLEQNLKSIKNSIERENLIPLPDEKSDESAALLIKSVRRSGSAANQFKNDLESRCVVYEQTNGEDSYQNLENLDVAGQKARELSMALDRLVHAARGVAASIEFENQESENNDKNLEKLAQLQIVNNCLEAVKAARDLVIEAKS---SPPDNDQMDRAQQASVRXXXXXXXXXXXXPGQRDLDMLSKHIESKKHQFAENRLPIQQNNNINLSNCRSELTDTTFDFNQAVNELVSAPSFNLVNKGCKKMRMSYDRIVEICNVLVHDPFDESDSALHHLSSNRD---HIANGVMIMSEDCQTLLDKVKKIQCEPDNIIVRKQLQEATKMLLDSINRLLTNISTNLRPGQKECDKTIYRLESMRPILDNPVHPISHKDYFECLDFIIDKTVQPLADSLKNIPAAVKDENNQKFIDSIYHCADSVCMLLEETAQTAYLVGVGDVRSKIGNKGLADHTSFLQIQKEISENCQTICNPDTTARQDSSLMISTAGQIAENSRKLCEASK--TIMISFPNDKIKLSDKTKITLLAVSELMTGVQNLNQNFNEDNRKEVESLSGKVQDNVAELVQLLLSYKFAGDAAIISEEAKESQGPIKAAGITVLDTAIEVIQCSKALISSEANEELFIAYSSSCKDLNDALKHLISTIKESAPGQKECDEXXXXXXXXXXQAYDSKMKIMKHRSRTISRTFESEESYQN--ILQSALIQMPHCINELSRAGKKEPEQLARIFSRQTQLLESMVNSCICAANQTDLIQNSNIYLEHLITILEASEQLLKAVKKSGGNPKANSVHSQIDEMAQGVIESCEDLLAALDKISFKQGNVNTIVETITKSSAKVQESAIIPEKSRFGNSQSKMLDICYDMNNLTTDISSNANSESTQRLLAPLTQNLTQRYDDLCRACQGAVATLSNENNGKQLQECVQTVGKVSISLVK--STTEVRPSVASSISNLQAKTQELHKRIDDVIQLLISSNVGTQACTQAIKILKEINSDIDTSILFVKSADIQNDDREYYSVKELFKKSRNSVIDNSSELVRNIKLIVSKDVCDVNILQESADQIAITSQSLANDVKVGLEHLNSSTSQYNIELLVSFQEVIVSLISFLEVARNTSGLPYTDPLFQNLKEEGKCSINAITSLLKVLKSMDDVNLKDFQAIDNAIIXXXXXXXXXXXXXXGISREASPVESPTSTNRLSIGSDITVSPRFAPEEINRLIPSLANVCDKILEISSPEFKPIIRQENISVVSISCSKVNNELTSACKNLLRNGPV-TDSKKQTLNTVDQLVENYTELLKNFKLYLTNPTKETR----IPVETVVSKLNELIK 7308
L+I + +V K + +P ++ C IR+ + EAQ+ +GL+L +D +KG+WL+ +TL +Y+L+ GD +EY+ + R IR +DG K + VDDS TV EL++T+C+++GI NY+EYSLI + M+ ++T ++K+ ++ +D++K++KLK K HTED LNWL+ S++ R+QG++E+E LLL+RK+F+SD NVDSRDP+QL+LLY Q +D ++NG+HPV+ +A E G+Q Q+Q G + K KPGFL+L+E LPKEY K + EKKIF +H +++E+EAK KY L RS +TYG++FFLVKEK+ GKNKL+PRLLG+ K+SV++VDEKTKE++ WPLT++++WAAS FT+DFGEY + YY+ QT +GE+ISQLIAGYIDIILK+K++KD G++ DEES M EE+++P K+ I++ ++ + K + ++ ++ S +T ++G S LTT MH M Q+ + ++ ++ +Q+ L + P +G D AS+ WI +D S+ + ++ A+ A A V+ G T + I+ S L +LME DE SGE+L+ AA+ LA A ++L+ A P + R+ + AA ++G+AS +LL+QI E E D+ +Q+ L+ LAK+VAN L+ + K +A E+ Q +V+ AAT+ L+ SQL++ K+V+PTI VCQEQLI + + V ++++ V + + AT+ EL AA+ V +AL+ L++H+R+ + + + + A + I + + S D ++V AR LAQAT+ +++ ++ A E + KL+ AAK LA++T ++++AK + + + + LREA E V T I++++++ L AA++AA T I S +A + K+ A++ ++ + +++ I L+ ++ ++ +D AQL LI + ++++ P ++ S K PTV+D + L+Q + EL+ +A C +++ +AL ++ L+ L+ K + L PLP E ++ A L + + GS+ Q C G + Y G ARE + AL L AARGVAAS S+ ++++ + ++ + +L+ EAK +P D + R Q + +S +L+ C++ LPGQ+D+DM K I + + LP + + +SEL D NQ+ E+V A + S D D F ++ + + N+D + + +S LL K + + + L A + + +SIN+L+T + T PGQKECD + LE+++ +L+NP P S YF+C++ +++ + + L +S+ I K + F + + + ++C L E Q AYLVG+ D S+ G +GL D F + + I CQ + +P ++ Q ++S A +A+++ LC A + + + P K K + + L+ ++ L+ +F+E+NR + + + V L + +FA A IS E +Q PI + +T+L+++ +I+ +++L + + + + + + ++D++K LI++I++ APGQ+ECD Q+ DS + ++ + + + + ++ L+ + Q+ H + QLAR F E +V + + ++ Q L+ T+ E++ Q+L A K+ GGNPKA H I E AQ + E+ +DL+ L++ + + G V +V++I ++ +K+ E F + Q+ + Y T S + L L +T Y +L + A AT + G Q++ +Q +G I LV+ ++ P+ + + L + + +++ V+ L + N GTQAC A + I +D+DT+I+F + + ++ KE F R +++ + LV + KL+VS L ++A A T LA VK+G L S + + L+ + ++V +L +E + +G DP LK K + +TSLLK +K+++D + +A++ I I +E + +S + S +PEE R+ + K + + RQE++ + K +E+ +ACK + + V D++++ + Y E+L++ L P+ ET+ I + + + + ELI+
Sbjct: 8 LSLKICVRQCNVVKTMQFEPSTAVYDACRIIRERVSEAQSGQALDFGLFLSDEDPRKGIWLEAGRTLDYYMLRNGDVLEYKKKHRPQKIRMLDGAAKMILVDDSKTVGELLVTICSRIGITNYEEYSLIRETME-EKKEEQTGTLKKDRTLLRDEKKMEKLKAKLHTEDELNWLDHSRTFREQGVDENETLLLRRKFFYSDQNVDSRDPVQLNLLYVQARDDILNGSHPVSFDKACEFGGIQAQIQFGPHVESKHKPGFLELKEFLPKEYMKQ-RGAEKKIFQEHKNCGEMTEIEAKVKYVKLARSLRTYGVSFFLVKEKMKGKNKLVPRLLGITKDSVMRVDEKTKEVLQEWPLTTVKRWAASPKSFTLDFGEYQ-ESYYSVQTTEGEQISQLIAGYIDIILKKKQSKDRFGLEGDEESTMLEESVSPKKSTILQ-----------QQQITRPGKPELGTVALPAIIRSGSS----------------GPETFNVGSMPSAQQQLTTGQMHRGHMPPLTSAQQALMGTINTSMHAVQQAHSDLSQVDNLPPLGHDMASRVWIQNKVDESKHEIHSQVDAITAGTASVVNLTAGDPTETDYTAVGCAITTISSNLTEMSKGVKLLAALME-------------DEVGSGEKLLGAARTLAGAVSDLLTAVQPSSGEP----RQTVLTAAGSIGQASGELLRQIGE-------------------NEADERFQDVLMNLAKAVANAAAMLVLKAKNVAQVTEDTVLQNRVIAAATQCALSTSQLVACAKVVSPTISSPVCQEQLIEAGKLVDRSVENCVHACHSATEDIELLKQVSAAASVVSQALNDLLQHVRQFASRGEPIGRYDQATDTIMSVTESIFSSMGDAGEMVRQARVLAQATSDLVNAMRSDA--EAEIDMDNSKKLLAAAKLLADSTARMVEAAKGAAANPENEDQQQRLREAAEGLRVAT-NAAAQNAIKKKIVNRLEAAAKQAAAAATQTIAASQNASLSNKNTAAHQQLVQSCKTVADHIPQLVQGVRSSQAQAEDLSAQLTLIVSSQNFLQPGSKMVASAKAAVPTVTDQAAAMQLSQCAKNLATSLAELRTAAQKAHEACGPMEIDSALNAVQTLKNELQDAKMAASDRQLKPLPGETLEKCAQDLGSTSKTVGSSMAQLLT-----CAA----QGNEHY--------TGVAARETAQALKTLAQAARGVAASTSDPQAASD-------------MLDSARDVMEGSANLIQEAKQALVAPGDAEIQQRLAQVAKAVSHSLNNCVNCLPGQKDVDMALKSIGESSKKLLVDSLP---PSTKSFQEAQSELNQAAEDLNQSAGEVVHASRGQSGELAAASGKFSQD----------FDEFLDAGIEMAGQTQNKDDQMQVIGSLKTISMASSKLLLAAKSLSVDSGAPSAKNLLAAAARAVTESINQLIT-LCTQQAPGQKECDNALRELETVKGMLENPNEPASDLSYFDCIESVMENS-KVLGESMAGISQNAKTGDLPAFGECVSVASKALCGLTEAAVQAAYLVGISDPNSQAGQQGLVDPIQFARANQAIQMACQNLVDPASSPSQ----VLSAATIVAKHTSALCNACRIASSKTANPVAKRHFVQSAKEVANSTANLVKTIKTLDGDFSEENRNKCSIATSPLISAVENLTAFASNPEFASIPAQISSEGARAQEPILVSAVTMLESSSSLIKTARSLAINPKDPPTWSSLAGHSRIVSDSIKSLITSIRDKAPGQRECD-----------QSIDSINRFIRDIEQASLASVSQDLAMRDDISLEVSAAQLGHKVT-----------QLARYF-------EPLVLAAVGLVSKVLDHQQQMTVLDQTKTLAESALQMLYAAKEGGGNPKAFHTHDAIAEAAQLMKEAVDDLMITLNEAASEVGMVGGMVDSIAEAMSKLDEGTPPEPTGTFVDYQTT--GVKYSKAIAVTAQEMMTKSVTNPEELGGLASQVTSDYGNLAVQGRMAAATAEPKEVGFQIKSRIQDLGHGCIFLVQKAGALQICPTDSYTKRELIECARAVTEKVSLVLSALQAGNKGTQACITASSAVSGIIADLDTTIMFATAGTLNAEN------KESFADHRENILKTAKALVEDTKLLVSGAASSQEKLAQAAQSSANTITQLAEVVKLGAASLGSDDPETQVVLINAIKDVAKALGDLIEATKCAAGKAADDPSMYQLKSAAKVMVTNVTSLLKTVKAVEDEATRGTRALEATI--------------EHIKQELTVFQSKDIPEKTS-----------SPEESIRMTKGITTATAKAVAAGNS-----CRQEDVIATANLSRKAVSEMLTACKQAVYHPDVNADTRQRAFRYGTECTFAYLEMLEHVLSILQKPSLETKQQLSIFSKRIAAAVTELIQ 2266
BLAST of Talin-1 vs. Ensembl Xenopus
Match: TLN2 (talin 2 [Source:NCBI gene;Acc:100144637]) HSP 1 Score: 827.78 bits (2137), Expect = 0.000e+0 Identity = 588/1916 (30.69%), Postives = 1011/1916 (52.77%), Query Frame = 1
Query: 49 FELRIHIVDADVTKIVPLDPEATIFQLCETIRKNIREAQTKSPKSYGLYLPHDDLKKGLWLDNSKTLQHYILKRGDTIEYRNRSRWLHIRTMDGTNKTLKVDDSWTVSELMLTVCTKLGIYNYDEYSLISDKMDFSPGIDKTLSMKRGISINXXXXXXXXXXXXYHTEDGLNWLNPSQSLRQQGIEESEVLLLKRKYFFSDMNVDSRDPIQLSLLYEQLKDAVINGTHPVTLPEAIELAGLQCQVQLGNYSADKFKPGFLDLRECLPKEYQKNPKTVEKKIFNQHSKSKDLSEVEAKEKYCLLCRSFKTYGITFFLVKEKVIGKNKLIPRLLGVNKESVVQVDEKTKEIINTWPLTSIRKWAASFNGFTMDFGEYSPDEYYTAQTDKGERISQLIAGYIDIILKRKKAKDHLGVDADEESIMYEENIAPSKAIIVEHVPKQKRSSVSEEDVVIRKKAHMANSSVRMNSQASDSVCSQDCTDFYQEDINMSRQTSSLGRTQSPSSSLTTNSMHY-RMSDDDIRQKLYIISLQDNLDTIQKYKDQLMIENKGPEIGKDEASQQWIYVNIDNSRQRMADEIGAMNAAVAQVLRSAQGLATIXXXXXXXXXXXXIAKMQNSFSLITVHLPSLMEEIRTAAYYQDQLTDEDVSGEELIAAAKRLADAFTNLIKAAYPVEDQKRSLNRKEIFDAANAVGEASSDLLQQITEQENCQIELKSERPYSIIMITEEDQLYQEELLRLAKSVANETTNLIKQVKVIAVEAENPSDQKKVVMAATETGLAISQLISTTKIVAPTIEQSVCQEQLIFSIEDVSKAIQVVVESSNKATQSEELQDLTVQAANQVQEALDTLMKHLRXXXXXXXXXXXXXXAYENI----QEXXXXXXXXXXXXXXXRRLAQATTAMISEIQLKAVNEQYKTPEERDKLINAAKQLAEATTVLIDSAKNCTMDKDEMNLRYTLREATERFIVVTYTTECATYIQEQVIDHLLVAARKAATTGTHLINTSLSA--AKKSRASNFKVCNDGRELSNQISNLIVAIKEARRDPKDHLAQLELIAACRDYIDPSEQLSQSNKYMWPTVSDPSLQTALNQSINQSVIATEELKKCVHQADLMCQHLDLSAALEQLKRLEQNLKSIKNSIERENLIPLPDEKSDESAALLIKSVRRSGSAANQFKNDLESRCVVYEQTNGEDSYQNLENLDVAGQKARELSMALDRLVHAARGVAASIEFENQESENNDKNLEKLAQLQIVNNCLEAVKAARDLVIEAKS---SPPDNDQMDRAQQASVRXXXXXXXXXXXXPGQRDLDMLSKHIESKKHQFAENRLPIQQNNNINLSNCRSELTDTTFDFNQAVNELVSAPSFNLVNKGCKKMRMSYDRIVEICNVLVHDPFDESDSALHHLSSNRD---HIANGVMIMSEDCQTLLDKVKKIQCEPDNIIVRKQLQEATKMLLDSINRLLTNISTNLRPGQKECDKTIYRLESMRPILDNPVHPISHKDYFECLDFIIDKTVQPLADSLKNIPAAVKDENNQKFIDSIYHCADSVCMLLEETAQTAYLVGVGDVRSKIGNKGLADHTSFLQIQKEISENCQTICNPDTTARQDSSLMISTAGQIAENSRKLCEASK--TIMISFPNDKIKLSDKTKITLLAVSELMTGVQNLNQNFNEDNRKEVESLSGKVQDNVAELVQLLLSYKFAGDAAIISEEAKESQGPIKAAGITVLDTAIEVIQCSKALISSEANEELFIAYSSSCKDLNDALKHLISTIKESAPGQKECDEXXXXXXXXXXQAYDSKMKIMKHRSR----TISRTFE-----SEESYQNILQSALIQMPHCINELSRAGKKEPEQLARIFSRQTQLLESMVNSCICAANQTDLIQNSNIYLEHLITILEASEQLLKAVKKSGGNPK 5724
L+I + +V K + +P ++ C IR+ + EAQ+ +GL+L +D +KG+WL+ +TL +Y+L+ GD +EY+ + R IR +DG K + VDDS TV EL++T+C+++GI NY+EYSLI + M+ ++T ++K+ ++ +D++K++KLK K HTED LNWL+ S++ R+QG++E+E LLL+RK+F+SD NVDSRDP+QL+LLY Q +D ++NG+HPV+ +A E G+Q Q+Q G + K KPGFL+L+E LPKEY K + EKKIF +H +++E+EAK KY L RS +TYG++FFLVKEK+ GKNKL+PRLLG+ K+SV++VDEKTKE++ WPLT++++WAAS FT+DFGEY + YY+ QT +GE+ISQLIAGYIDIILK+K++KD G++ DEES M EE+++P K+ I++ ++ + K + ++ ++ S +T ++G S LTT MH M Q+ + ++ ++ +Q+ L + P +G D AS+ WI +D S+ + ++ A+ A A V+ G T + I+ S L +LME DE SGE+L+ AA+ LA A ++L+ A P + R+ + AA ++G+AS +LL+QI E E D+ +Q+ L+ LAK+VAN L+ + K +A E+ Q +V+ AAT+ L+ SQL++ K+V+PTI VCQEQLI + + V ++++ V + + AT+ EL AA+ V +AL+ L++H+R+ + + + + A + I + + S D ++V AR LAQAT+ +++ ++ A E + KL+ AAK LA++T ++++AK + + + + LREA E V T I++++++ L AA++AA T I S +A + K+ A++ ++ + +++ I L+ ++ ++ +D AQL LI + ++++ P ++ S K PTV+D + L+Q + EL+ +A C +++ +AL ++ L+ L+ K + L PLP E ++ A L + + GS+ Q C G + Y G ARE + AL L AARGVAAS S+ ++++ + ++ + +L+ EAK +P D + R Q + +S +L+ C++ LPGQ+D+DM K I + + LP + + +SEL D NQ+ E+V A + S D D F ++ + + N+D + + +S LL K + + + L A + + +SIN+L+T + T PGQKECD + LE+++ +L+NP P S YF+C++ +++ + + L +S+ I K + F + + + ++C L E Q AYLVG+ D S+ G +GL D F + + I CQ + +P ++ Q ++S A +A+++ LC A + + + P K K + + L+ ++ L+ +F+E+NR + + + V L + +FA A IS E +Q PI + +T+L+++ +I+ +++L + + + + + + ++D++K LI++I++ APGQ+ECD Q+ DS + ++ + ++S+ S E+ Q L S + ++ H I+ ++ A + E QL ++ + E +V + + ++ Q L+ T+ E++ Q+L A K+ GGNPK
Sbjct: 4 LSLKICVRQCNVVKTMQFEPSTAVYDACRIIRERVSEAQSGQALDFGLFLSDEDPRKGIWLEAGRTLDYYMLRNGDVLEYKKKHRPQKIRMLDGAAKMILVDDSKTVGELLVTICSRIGITNYEEYSLIRETME-EKKEEQTGTLKKDRTLLRDEKKMEKLKAKLHTEDELNWLDHSRTFREQGVDENETLLLRRKFFYSDQNVDSRDPVQLNLLYVQARDDILNGSHPVSFDKACEFGGIQAQIQFGPHVESKHKPGFLELKEFLPKEYMKQ-RGAEKKIFQEHKNCGEMTEIEAKVKYVKLARSLRTYGVSFFLVKEKMKGKNKLVPRLLGITKDSVMRVDEKTKEVLQEWPLTTVKRWAASPKSFTLDFGEYQ-ESYYSVQTTEGEQISQLIAGYIDIILKKKQSKDRFGLEGDEESTMLEESVSPKKSTILQ-----------QQQITRPGKPELGTVALPAIIRSGSS----------------GPETFNVGSMPSAQQQLTTGQMHRGHMPPLTSAQQALMGTINTSMHAVQQAHSDLSQVDNLPPLGHDMASRVWIQNKVDESKHEIHSQVDAITAGTASVVNLTAGDPTETDYTAVGCAITTISSNLTEMSKGVKLLAALME-------------DEVGSGEKLLGAARTLAGAVSDLLTAVQPSSGEP----RQTVLTAAGSIGQASGELLRQIGE-------------------NEADERFQDVLMNLAKAVANAAAMLVLKAKNVAQVTEDTVLQNRVIAAATQCALSTSQLVACAKVVSPTISSPVCQEQLIEAGKLVDRSVENCVHACHSATEDIELLKQVSAAASVVSQALNDLLQHVRQFASRGEPIGRYDQATDTIMSVTESIFSSMGDAGEMVRQARVLAQATSDLVNAMRSDA--EAEIDMDNSKKLLAAAKLLADSTARMVEAAKGAAANPENEDQQQRLREAAEGLRVAT-NAAAQNAIKKKIVNRLEAAAKQAAAAATQTIAASQNASLSNKNTAAHQQLVQSCKTVADHIPQLVQGVRSSQAQAEDLSAQLTLIVSSQNFLQPGSKMVASAKAAVPTVTDQAAAMQLSQCAKNLATSLAELRTAAQKAHEACGPMEIDSALNAVQTLKNELQDAKMAASDRQLKPLPGETLEKCAQDLGSTSKTVGSSMAQLLT-----CAA----QGNEHY--------TGVAARETAQALKTLAQAARGVAASTSDPQAASD-------------MLDSARDVMEGSANLIQEAKQALVAPGDAEIQQRLAQVAKAVSHSLNNCVNCLPGQKDVDMALKSIGESSKKLLVDSLP---PSTKSFQEAQSELNQAAEDLNQSAGEVVHASRGQSGELAAASGKFSQD----------FDEFLDAGIEMAGQTQNKDDQMQVIGSLKTISMASSKLLLAAKSLSVDSGAPSAKNLLAAAARAVTESINQLIT-LCTQQAPGQKECDNALRELETVKGMLENPNEPASDLSYFDCIESVMENS-KVLGESMAGISQNAKTGDLPAFGECVSVASKALCGLTEAAVQAAYLVGISDPNSQAGQQGLVDPIQFARANQAIQMACQNLVDPASSPSQ----VLSAATIVAKHTSALCNACRIASSKTANPVAKRHFVQSAKEVANSTANLVKTIKTLDGDFSEENRNKCSIATSPLISAVENLTAFASNPEFASIPAQISSEGARAQEPILVSAVTMLESSSSLIKTARSLAINPKDPPTWSSLAGHSRIVSDSIKSLITSIRDKAPGQRECD-----------QSIDSINRFIRDIEQASLASVSQDLAMRDDISLEALQEQLTSVVQEIGHLIDPITTAARGEAAQLGHKVTQLARYFEPLVLAAVGLVSKVLDHQQQMTVLDQTKTLAESALQMLYAAKEGGGNPK 1790 HSP 2 Score: 91.6633 bits (226), Expect = 4.228e-17 Identity = 97/419 (23.15%), Postives = 186/419 (44.39%), Query Frame = 1
Query: 6073 AVATLSNENNGKQLQECVQTVGKVSISLVK--STTEVRPSVASSISNLQAKTQELHKRIDDVIQLLISSNVGTQACTQAIKILKEINSDIDTSILFVKSADIQNDDREYYSVKELFKKSRNSVIDNSSELVRNIKLIVSKDVCDVNILQESADQIAITSQSLANDVKVGLEHLNSSTSQYNIELLVSFQEVIVSLISFLEVARNTSGLPYTDPLFQNLKEEGKCSINAITSLLKVLKSMDDVNLKDFQAIDNAIIXXXXXXXXXXXXXXGISREASPVESPTSTNRLSIGSDITVSPRFAPEEINRLIPSLANVCDKILEISSPEFKPIIRQENISVVSISCSKVNNELTSACKNLLRNGPV-TDSKKQTLNTVDQLVENYTELLKNFKLYLTNPTKETR----IPVETVVSKLNELIK 7308
A+A + E G Q++ +Q +G I LV+ ++ P+ + + L + + +++ V+ L + N GTQAC A + I +D+DT+I+F + + ++ KE F R +++ + LV + KL+VS L ++A A T LA VK+G L S + + L+ + ++V +L +E + +G DP LK K + +TSLLK +K+++D + +A++ I I +E + +S + S +PEE R+ + K + + RQE++ + K +E+ +ACK + + V D++++ + Y E+L++ L P+ ET+ I + + + + ELI+
Sbjct: 1816 AIAVTAQEMVGFQIKSRIQDLGHGCIFLVQKAGALQICPTDSYTKRELIECARAVTEKVSLVLSALQAGNKGTQACITASSAVSGIIADLDTTIMFATAGTLNAEN------KESFADHRENILKTAKALVEDTKLLVSGAASSQEKLAQAAQSSANTITQLAEVVKLGAASLGSDDPETQVVLINAIKDVAKALGDLIEATKCAAGKAADDPSMYQLKSAAKVMVTNVTSLLKTVKAVEDEATRGTRALEATI--------------EHIKQELTVFQSKDIPEKTS-----------SPEESIRMTKGITTATAKAVAAGNS-----CRQEDVIATANLSRKAVSEMLTACKQAVYHPDVNADTRQRAFRYGTECTFAYLEMLEHVLSILQKPSLETKQQLSIFSKRIAAAVTELIQ 2198
BLAST of Talin-1 vs. Ensembl Mouse
Match: Tln1 (talin 1 [Source:MGI Symbol;Acc:MGI:1099832]) HSP 1 Score: 962.214 bits (2486), Expect = 0.000e+0 Identity = 696/2283 (30.49%), Postives = 1176/2283 (51.51%), Query Frame = 1
Query: 55 LRIHIVDADVTKIVPLDPEATIFQLCETIRKNIREAQTKSPKSYGLYLPHDDLKKGLWLDNSKTLQHYILKRGDTIEYRNRSRWLHIRTMDGTNKTLKVDDSWTVSELMLTVCTKLGIYNYDEYSLISDKMDFSPGIDKTLSMKRGISINXXXXXXXXXXXXYHTEDGLNWLNPSQSLRQQGIEESEVLLLKRKYFFSDMNVDSRDPIQLSLLYEQLKDAVINGTHPVTLPEAIELAGLQCQVQLGNYSADKFKPGFLDLRECLPKEYQKNPKTVEKKIFNQHSKSKDLSEVEAKEKYCLLCRSFKTYGITFFLVKEKVIGKNKLIPRLLGVNKESVVQVDEKTKEIINTWPLTSIRKWAASFNGFTMDFGEYSPDEYYTAQTDKGERISQLIAGYIDIILKRKKAKDHLGVDADEESIMYEENIAPSKAIIVEH----VPKQKRSSVSEEDVVIRKKAHMANSSVRMNSQASDSVCSQDCTDFYQEDINMSRQTSSLGRTQSPSSSLTTNSMHY-RMSDDDIRQKLYIISLQDNLDTIQKYKDQLMIENKGPEIGKDEASQQWIYVNIDNSRQRMADEIGAMNAAVAQVLRSAQGLATIXXXXXXXXXXXXIAKMQNSFSLITVHLPSLMEEIRTAAYYQDQLTDEDVSGEELIAAAKRLADAFTNLIKAAYPVEDQKRSLNRKEIFDAANAVGEASSDLLQQITEQENCQIELKSERPYSIIMITEEDQLYQEELLRLAKSVANETTNLIKQVKVIAVEAENPSDQKKVVMAATETGLAISQLISTTKIVAPTIEQSVCQEQLIFSIEDVSKAIQVVVESSNKATQSEELQDLTVQAANQVQEALDTLMKHLRXXXXXXXXXXXXXXAYENI----QEXXXXXXXXXXXXXXXRRLAQATTAMISEIQLKAVNEQYKTPEERDKLINAAKQLAEATTVLIDSAKNCTMDKDEMNLRYTLREATERFIVVTYTTECATYIQEQVIDHLLVAARKAATTGTHLINTSLSAAKKSRASNFK---VCNDGRELSNQISNLIVAIKEARRDPKDHLAQLELIAACRDYIDPSEQLSQSNKYMWPTVSDPSLQTALNQSINQSVIATEELKKCVHQADLMCQHLDLSAALEQLKRLEQNLKSIKNSIERENLIPLPDEKSDESAALLIKSVRRSGSAANQFKNDLESRCVVYEQTNGEDSYQNLENLDVAGQKARELSMALDRLVHAARGVAASIEFENQESENNDKNLEKLAQLQIVNNCLEAVKAARDLVIEAKSS---PPDNDQMDRAQQASVRXXXXXXXXXXXXPGQRDLDMLSKHIESKKHQFAENRLPIQQNNNINLSNCRSELTDTTFDFNQAVNELVSAPSFNLVNKGCKK-MRMSYDRIVEICNVLVHDPFDESDSALHHLSSNRDHIANGVMIMSEDCQTLLDKVKKIQCEPDNIIVRKQLQEATKMLLDSINRLLTNISTNLRPGQKECDKTIYRLESMRPILDNPVHPISHKDYFECLDFIIDKTVQPLADSLKNIPAAVKDENNQKFIDSIYHCADSVCMLLEETAQTAYLVGVGDVRSKIGNKGLADHTSFLQIQKEISENCQTICNPDTTARQDSSLMISTAGQIAENSRKLCEASK--TIMISFPNDKIKLSDKTKITLLAVSELMTGVQNLNQNFNEDNRKEVESLSGKVQDNVAELVQLLLSYKFAGDAAIISEEAKESQGPIKAAGITVLDTAIEVIQCSKALISSEANEELFIAYSSSCKDLNDALKHLISTIKESAPGQKECDEXXXXXXXXXXQAYDSKMKIMKHRS------RTISRTFESEESYQNILQSALIQMPHCINELSRAGKKEPEQLARIFSRQTQLLESMVNSCICAANQTDLIQNSNIYLEHLITILEASEQLLKAVKKSGGNPKANSVHSQ--IDEMAQGVIESCEDLLAALDKISFKQGNVNTIVETITKSSAKVQESAIIPEKSRFGNSQSKMLDICYDMNNLTTDISSNANSESTQRLLAPLTQNLTQRYDDLCRACQGAVATLSNENNGKQLQECVQTVGKVSISLVKSTTEVR--PSVASSISNLQAKTQELHKRIDDVIQLLISSNVGTQACTQAIKILKEINSDIDTSILFVKSADIQNDDREYYSVKELFKKSRNSVIDNSSELVRNIKLIVSKDVCDVNILQESADQIAITSQSLANDVKVGLEHLNSSTSQYNIELLVSFQEVIVSLISFLEVARNTSGLPYTDPLFQNLKEEGKCSINAITSLLKVLKSMDDVNLKDFQAID 6819
L + I +V K + +P ++ C IR+ I EA P +GL+L DD KKG+WL+ K L +Y+L+ GDT+EYR + R L IR +DGT KT+ VDDS TV+++++T+C ++GI N+DEYSL+ + M+ + T ++++ ++ +D++K++KLK+K HT+D LNWL+ ++LR+QG+EE E LLL+RK+F+SD NVDSRDP+QL+LLY Q +D ++NG+HPV+ +A E AG QCQ+Q G ++ K K GFLDL++ LPKEY K + E+KIF H +SE+EAK +Y L RS KTYG++FFLVKEK+ GKNKL+PRLLG+ KE V++VDEKTKE+I W LT+I++WAAS FT+DFG+Y D YY+ QT +GE+I+QLIAGYIDIILK+KK+KDH G++ DEES M E++++P K+ +++ V K + SV+ + M S AS + +Q +G +T+ MH M Q+ ++ ++ +Q + L P +G+D AS+ W +D S+ + ++ A+ A A V+ G + E + + + I+ +L + ++ A L DE +G L+ AAK LA A + L+++A P + R + + AA VG+AS +LLQQI E ++ D +Q+ L++LAK+VA+ L+ + K +A E+ Q +V+ AAT+ L+ SQL++ TK+VAPTI VCQEQL+ + V+KA++ V +S AT+ +L AA V +AL+ L++H++ + A + I + + S D ++V AR LAQAT+ +++ I KA E E KL++AAK LA+AT ++++AK D + LREA E + T I+++++ L AA++AA + T I + AA +AS + + ++ QI L+ ++ ++ P AQL LIAA + ++ P ++ + K PT+ D + L+Q A EL+ +A C L++ +AL ++ LE++L+ IK + L PLP E ++ L S + SA + ++ G ++Y + DVAG L L AARGVAA +D ++ + +++ + + A L+ EAK + P D + R Q + ++ AL+ C+ LPGQRD+D + + + + LP + +S L + NQA ELV A ++G + + + R + + + + + A +R + + + +S LL K + +P + ++ QL A + + DSIN+L+T + T PGQKECD + +LE++R +L+NPV PI+ YF CLD +++ + + L +++ I K+ N +F D+I + ++C E AQ AYLVGV D S+ G +GL + T F + + I CQ++ P T Q ++S A +A+++ LC + + + + P K + K + + L+ ++ L+ +F E+NR + + + + + V L + +F+ A IS E + + PI + T+L++A +IQ ++AL + + + + + ++D++K LI+++++ APGQ EC+ A +S ++ + S + R S+E+ + +A+ ++ H I L+ A + E QL S+ Q E + + + AA++T L+ T+ E++ QLL K++GGNPK + H+Q ++E Q + E+ EDL L++ + G V +V++IT++ ++ E + + F + Q+ M+ + ++ + +N+ + L PL LT Y L + A NE G ++ VQ +G +LV ++ PS + L + + +++ V+ L + N GTQAC A + I +D+DT+I+F + + +RE E F R ++ + LV + K++V L ++A T LA+ VK+G L + + + L+ + ++V +L + + +G DP LK K + +TSLLK +K+++D K +A++
Sbjct: 4 LSLKISIGNVVKTMQFEPSTMVYDACRMIRERIPEALAGPPNDFGLFLSDDDPKKGIWLEAGKALDYYMLRNGDTMEYRKKQRPLKIRMLDGTVKTIMVDDSKTVTDMLMTICARIGITNHDEYSLVRELMEEKKD-EGTGTLRKDKTLLRDEKKMEKLKQKLHTDDELNWLDHGRTLREQGVEEHETLLLRRKFFYSDQNVDSRDPVQLNLLYVQARDDILNGSHPVSFDKACEFAGFQCQIQFGPHNEQKHKAGFLDLKDFLPKEYVK--QKGERKIFQAHKNCGQMSEIEAKVRYVKLARSLKTYGVSFFLVKEKMKGKNKLVPRLLGITKECVMRVDEKTKEVIQEWSLTNIKRWAASPKSFTLDFGDYQ-DGYYSVQTTEGEQIAQLIAGYIDIILKKKKSKDHFGLEGDEESTMLEDSVSPKKSTVLQQQYNRVGKVEHGSVALPAI--------------MRSGASGP-------ENFQ-----------VGSMPPAQQQITSGQMHRGHMPPLTSAQQALTGTINSSMQAVQAAQATLDDFETLPPLGQDAASKAWRKNKMDESKHEIHSQVDAITAGTASVVNLTAG----------DPAETDYTAVGCAVTTISSNLTEMSRGVKLLAAL---LEDEGGNGRPLLQAAKGLAGAVSELLRSAQPASAEPR----QNLLQAAGNVGQASGELLQQIGE-------------------SDTDPHFQDVLMQLAKAVASAAAALVLKAKSVAQRTEDSGLQTQVIAAATQCALSTSQLVACTKVVAPTISSPVCQEQLVEAGRLVAKAVEGCVSASQAATEDGQLLRGVGAAATAVTQALNELLQHVKAHATGAGPAGRYDQATDTILTVTENIFSSMGDAGEMVRQARILAQATSDLVNAI--KADAEGESDLENSRKLLSAAKILADATAKMVEAAKGAAAHPDSEEQQQRLREAAEGLRMAT-NAAAQNAIKKKLVQRLEHAAKQAAASATQTIAAAQHAASAPKASAGPQPLLVQSCKAVAEQIPLLVQGVRGSQAQPDSPSAQLALIAASQSFLQPGGKMVAAAKASVPTIQDQASAMQLSQCAKNLGTALAELRTAAQKAQEACGPLEMDSALSVVQNLEKDLQEIKAAARDGKLKPLPGETMEKCTQDLGNSTKAVSSAIAKLLGEI---------AQGNENYAGIAARDVAG--------GLRSLAQAARGVAAL---------TSDPAVQAI----VLDTASDVLDKASSLIEEAKKASGHPGDPESQQRLAQVAKAVTQALNRCVSCLPGQRDVDNALRAVGDASKRLLSDSLP---PSTGTFQEAQSRLNEAAAGLNQAATELVQA------SRGTPQDLARASGRFGQDFSTFLEAGVEMAGQAPSQ--EDRAQVVSNLKGISMSSSKLLLAAKALSTDPASPNLKSQLAAAARAVTDSINQLIT-MCTQQAPGQKECDNALRQLETVRELLENPVQPINDMSYFGCLDSVMENS-KVLGEAMTGISQNAKNGNLPEFGDAIATASKALCGFTEAAAQAAYLVGVSDPNSQAGQQGLVEPTQFARANQAIQMACQSLGEPGCTQAQ----VLSAATIVAKHTSALCNSCRLASARTANPTAKRQFVQSAKEVANSTANLVKTIKALDGDFTEENRAQCRAATAPLLEAVDNLSAFASNPEFSSVPAQISPEGRAAMEPIVISAKTMLESAGGLIQTARALAVNPRDPPRWSVLAGHSRTVSDSIKKLITSMRDKAPGQLECE--------TAIAALNSCLRDLDQASLAAVSQQLAPREGISQEALHTQMLTAVQEISHLIEPLASAARAEASQLGHKVSQMAQYFEPLTLAAVGAASKTLSHPQQMALLDQTKTLAESALQLLYTAKEAGGNPK-QAAHTQEALEEAVQMMTEAVEDLTTTLNEAASAAGVVGGMVDSITQAINQLDEGPMGDPEGSFVDYQTTMVRTAKAIAVTVQEMVTKSNTSPEE--LGPLANQLTSDYGRLASQAKPAAVAAENEEIGAHIKHRVQELGHGCSALVTKAGALQCSPSDVYTKKELIECARRVSEKVSHVLAALQAGNRGTQACITAASAVSGIIADLDTTIMFATAGTL---NREGA---ETFADHREGILKTAKVLVEDTKVLVQNAAGSQEKLAQAAQSSVATITRLADVVKLGAASLGAEDPETQVVLINAVKDVAKALGDLISATKAAAGKVGDDPAVWQLKNSAKVMVTNVTSLLKTVKAVEDEATKGTRALE 2147
BLAST of Talin-1 vs. Ensembl Mouse
Match: Tln2 (talin 2 [Source:MGI Symbol;Acc:MGI:1917799]) HSP 1 Score: 933.324 bits (2411), Expect = 0.000e+0 Identity = 692/2281 (30.34%), Postives = 1187/2281 (52.04%), Query Frame = 1
Query: 49 FELRIHIVDADVTKIVPLDPEATIFQLCETIRKNIREAQTKSPKSYGLYLPHDDLKKGLWLDNSKTLQHYILKRGDTIEYRNRSRWLHIRTMDGTNKTLKVDDSWTVSELMLTVCTKLGIYNYDEYSLISDKMDFSPGIDKTLSMKRGISINXXXXXXXXXXXXYHTEDGLNWLNPSQSLRQQGIEESEVLLLKRKYFFSDMNVDSRDPIQLSLLYEQLKDAVINGTHPVTLPEAIELAGLQCQVQLGNYSADKFKPGFLDLRECLPKEYQKNPKTVEKKIFNQHSKSKDLSEVEAKEKYCLLCRSFKTYGITFFLVKEKVIGKNKLIPRLLGVNKESVVQVDEKTKEIINTWPLTSIRKWAASFNGFTMDFGEYSPDEYYTAQTDKGERISQLIAGYIDIILKRKKAKDHLGVDADEESIMYEENIAPSKAIIVEHVPKQKRSSVSEEDVVIRKKAHMANSSVRMNSQASDSVCSQDCTDFYQEDINMSRQTSSLGRTQSPSSSLTTNSMHY-RMSDDDIRQKLYIISLQDNLDTIQKYKDQLMIENKGPEIGKDEASQQWIYVNIDNSRQRMADEIGAMNAAVAQVLRSAQGLATIXXXXXXXXXXXXIAKMQNSFSLITVHLPSLMEEIRTAAYYQDQLTDEDV-SGEELIAAAKRLADAFTNLIKAAYPVEDQKRSLNRKEIFDAANAVGEASSDLLQQITEQENCQIELKSERPYSIIMITEEDQLYQEELLRLAKSVANETTNLIKQVKVIAVEAENPSDQKKVVMAATETGLAISQLISTTKIVAPTIEQSVCQEQLIFSIEDVSKAIQVVVESSNKATQSEELQDLTVQAANQVQEALDTLMKHLRXXXXXXXXXXXXXXAYENI----QEXXXXXXXXXXXXXXXRRLAQATTAMISEIQLKAVNEQYKTPEERDKLINAAKQLAEATTVLIDSAKNCTMDKDEMNLRYTLREATERFIVVTYTTECATYIQEQVIDHLLVAARKAATTGTHLINTSLSAA--KKSRASNFKVCNDGRELSNQISNLIVAIKEARRDPKDHLAQLELIAACRDYIDPSEQLSQSNKYMWPTVSDPSLQTALNQSINQSVIATEELKKCVHQADLMCQHLDLSAALEQLKRLEQNLKSIKNSIERENLIPLPDEKSDESAALLIKSVRRSGSAANQFKNDLESRCVVYEQTNGEDSYQNLENLDVAGQKARELSMALDRLVHAARGVAASIEFENQESENNDKNLEKLAQLQIVNNCLEAVKAARDLVIEAKS---SPPDNDQMDRAQQASVRXXXXXXXXXXXXPGQRDLDMLSKHIESKKHQFAENRLPIQQNNNINLSNCRSELTDTTFDFNQAVNELVSAPSFNLVNKGCKKMRMSYDRIVEICNVLVHDPFDESDSALHHLSS------NRDHIANGVMIMSEDCQTLLDKVKKIQCEPDNIIVRKQLQEATKMLLDSINRLLTNISTNLRPGQKECDKTIYRLESMRPILDNPVHPISHKDYFECLDFIIDKTVQPLADSLKNIPAAVKDENNQKFIDSIYHCADSVCMLLEETAQTAYLVGVGDVRSKIGNKGLADHTSFLQIQKEISENCQTICNPDTTARQDSSLMISTAGQIAENSRKLCEASK--TIMISFPNDKIKLSDKTKITLLAVSELMTGVQNLNQNFNEDNRKEVESLSGKVQDNVAELVQLLLSYKFAGDAAIISEEAKESQGPIKAAGITVLDTAIEVIQCSKALISSEANEELFIAYSSSCKDLNDALKHLISTIKESAPGQKECDEXXXXXXXXXXQAYDSKMKIMKHRSRTISRTFESEESYQNILQSALIQMPHCINELSRAGKKEPEQLARIFSRQTQLLESMVNSCICAANQTDLIQNSNIYLEHLITILEASEQLLKAVKKSGGNPKANSVHSQIDEMAQGVIESCEDLLAALDKISFKQGNVNTIVETITKSSAKVQESAIIPEKSRFGNSQSKMLDICYDMNNLTTDISSNANSESTQRLLAPLTQNLTQRYDDLCRACQGAVATLSNENNGKQLQECVQTVGKVSISLVK--STTEVRPSVASSISNLQAKTQELHKRIDDVIQLLISSNVGTQACTQAIKILKEINSDIDTSILFVKSADIQNDDREYYSVKELFKKSRNSVIDNSSELVRNIKLIVSKDVCDVNILQESADQIAITSQSLANDVKVGLEHLNSSTSQYNIELLVSFQEVIVSLISFLEVARNTSGLPYTDPLFQNLKEEGKCSINAITSLLKVLKSMDDVNLKDFQAIDNAI 6828
L+I + +V K + +P ++ C IR+ + EAQT YGL+L +D +KG+WL+ +TL +Y+L+ GD +EY+ + R IR +DG+ KT+ VDDS TV EL++T+C+++GI NY+EYSLI + ++ + T ++K+ ++ +D+ K++KLK K HT+D LNWL+ S++ R+QG++E+E LLL+RK+F+SD NVDSRDP+QL+LLY Q +D ++NG+HPV+ +A E G Q Q+Q G + K KPGFLDL+E LPKEY K + EK+IF +H ++SE+EAK KY L RS +TYG++FFLVKEK+ GKNKL+PRLLG+ K+SV++VDEKTKE++ WPLT++++WAAS FT+DFGEY + YY+ QT +GE+ISQLIAGYIDIILK+K++KD G++ DEES M EE+++P K+ I++ + R+ +E V + SS +T ++G SP + MH M Q+ + ++ ++ +Q+ +D L + P +G+D AS+ W+ +D S+ + ++ A+ A A V+ G + + + + + I+ +L + + ++ A L D+DV SGE+L+ AA+ LA A ++L+KA P + R + + AA ++G+AS DLL+QI E E D+ +Q+ L+ LAK+VAN L+ + K +A AE+ Q +V+ AAT+ L+ SQL++ K+V+PTI VCQEQLI + + V ++++ V + AT EL AA+ V +AL L++H+R+ + + + + A + I + + S D ++V AR LAQAT+ +++ ++ A E E KL+ AAK LA++T ++++AK + + + + LREA E V T I++++++ L VAA++AA T I S +AA K+ ++ ++ + +++ I L+ ++ ++ +D AQL LI + ++++ P ++ S K PTVSD + L+Q + EL+ +A C +++ +AL ++ L+ L+ K + L PLP E ++ A L + + GS+ Q C G + Y G ARE + AL L AARGVAAS ND A ++++ + ++ + L+ EAK +P D + R Q + +S +L+ C++ LPGQ+D+D+ K I + + LP + +SEL D NQ+ E+V A + S D FDE A ++ ++ + + +S LL K + +P + L A + + +SIN+L+ + T PGQKECD + LE+++ +L+NP P+S YF+C++ +++ + + L +S+ I K + F + + + ++C L E AQ AYLVG+ D S+ G++GL D F + + I CQ + +P ++ Q ++S A +A+++ LC A + + + P K K + + L+ ++ L+ +F+EDNR + + + + V L + +FA A IS E ++Q PI + T+L+++ +I+ +++L + + + + ++D++K LI++I++ APGQ+ECD ++ + + I+ + + + T R S E+ Q L S + ++ H I+ ++ A + E QL ++ E ++ + + A++ Q L+ T+ E++ Q+L A K+ GGNPKA H I E AQ + E+ +D++ L++ + + G V +V+ I ++ +K+ E K F + Q+ ++ Y T S + L L +T Y L Q A AT E G Q++ VQ +G I LV+ +V P+ + + L + + +++ V+ L + N GTQAC A + I +D+DT+I+F + + ++ E F R +++ + LV + KL+VS + L ++A A T LA VK+G L S+ + + L+ + ++V +L + + + P DP LK K + +TSLLK +K+++D + +A++ I
Sbjct: 6 LSLKICVRHCNVVKTMQFEPSTAVYDACRVIRERVPEAQTGQASDYGLFLSDEDPRKGIWLEAGRTLDYYMLRNGDILEYKKKQRPQKIRMLDGSVKTVMVDDSKTVGELLVTICSRIGITNYEEYSLIQETIE-EKKEEGTGTLKKDRTLLRDERKMEKLKAKLHTDDDLNWLDHSRTFREQGVDENETLLLRRKFFYSDQNVDSRDPVQLNLLYVQARDDILNGSHPVSFEKACEFGGFQAQIQFGPHVEHKHKPGFLDLKEFLPKEYIKQ-RGAEKRIFQEHKNCGEMSEIEAKVKYVKLARSLRTYGVSFFLVKEKMKGKNKLVPRLLGITKDSVMRVDEKTKEVLQEWPLTTVKRWAASPKSFTLDFGEYQ-ESYYSVQTTEGEQISQLIAGYIDIILKKKQSKDRFGLEGDEESTMLEESVSPKKSTILQQ--QFNRTGKAEHGSVALPAVMRSGSS--------------------------GPETFNVGSMPSPQQQVMVGQMHRGHMPPLTSAQQALMGTINTSMHAVQQAQDDLSELDSLPPLGQDMASRVWVQNKVDESKHEIHSQVDAITAGTASVVNLTAG----------DPADTDYTAVGCAITTISSNLTEMSKGVKLLAA----LMDDDVGSGEDLLRAARTLAGAVSDLLKAVQPTSGEPR----QTVLTAAGSIGQASGDLLRQIGENET-------------------DERFQDVLMSLAKAVANAAAMLVLKAKNVAQVAEDTVLQNRVIAAATQCALSTSQLVACAKVVSPTISSPVCQEQLIEAGKLVDRSVENCVRACQAATSDSELLKQVSAAASVVSQALHDLLQHVRQFASRGEPIGRYDQATDTIMCVTESIFSSMGDAGEMVRQARVLAQATSDLVNAMRSDA--EAEIDMENSKKLLAAAKLLADSTARMVEAAKGAAANPENEDQQQRLREAAEGLRVAT-NAAAQNAIKKKIVNRLEVAAKQAAAAATQTIAASQNAAISNKNPSAQQQLVQSCKAVADHIPQLVQGVRGSQAQAEDLSAQLALIISSQNFLQPGSKMVSSAKAAVPTVSDQAAAMQLSQCAKNLATSLAELRTASQKAHEACGPMEIDSALNTVQTLKNELQDAKMAAAESQLKPLPGETLEKCAQDLGSTSKGVGSSMAQLLT-----CAA----QGNEHY--------TGVAARETAQALKTLAQAARGVAAS---------TNDPE----AAHAMLDSARDVMEGSAMLIQEAKQALIAPGDTESQQRLAQVAKAVSHSLNNCVNCLPGQKDVDVALKSIGEASKKLLVDSLP---PSTKPFQEAQSELNQAAADLNQSAGEVVHATRGQSGELAAASGKFS-------------DDFDEFLDAGIEMAGQAQTKEDQMQVIGNLKNISMASSKLLLAAKSLSVDPGAPNAKNLLAAAARAVTESINQLIM-LCTQQAPGQKECDNALRELETVKGMLENPNEPVSDLSYFDCIESVMENS-KVLGESMAGISQNAKTGDLPAFGECVGIASKALCGLTEAAAQAAYLVGISDPNSQAGHQGLVDPIQFARANQAIQMACQNLVDPGSSPSQ----VLSAATIVAKHTSALCNACRIASSKTANPVAKRHFVQSAKEVANSTANLVKTIKALDGDFSEDNRNKCRIATTPLIEAVENLTAFASNPEFASIPAQISSEGSQAQEPILVSAKTMLESSSYLIRTARSLAINPKDPPTWSVLAGHSHTVSDSIKSLITSIRDKAPGQRECDYSIDGINRCIRDIEQASLAAVSQSLAT--RDDISVEALQEQLTSVVQEIGHLIDPIATAARGEAAQLGHKVTQLASYFEPLILAAVGVASKMLDHQQQMTVLDQTKTLAESALQMLYAAKEGGGNPKAQHTHDAITEAAQLMKEAVDDIMVTLNEAASEVGLVGGMVDAIAEAMSKLDEGTPPEPKGTFVDYQTTVVK--YSKAIAVTAQEMMTKSVTNPEELGGLASQMTTDYGHLALQGQMAAATAEPEEIGFQIRTRVQDLGHGCIFLVQKAGALQVCPTDSYTKRELIECARSVTEKVSLVLSALQAGNKGTQACITAATAVSGIIADLDTTIMFATAGTLNAEN------GETFADHRENILKTAKALVEDTKLLVSGAASTPDKLAQAAQSSAATITQLAEVVKLGAASLGSNDPETQVVLINAIKDVAKALSDLIGATKGAASKPADDPSMYQLKGAAKVMVTNVTSLLKTVKAVEDEATRGTRALEATI 2153
BLAST of Talin-1 vs. Ensembl Mouse
Match: Tln2 (talin 2 [Source:MGI Symbol;Acc:MGI:1917799]) HSP 1 Score: 932.939 bits (2410), Expect = 0.000e+0 Identity = 692/2281 (30.34%), Postives = 1187/2281 (52.04%), Query Frame = 1
Query: 49 FELRIHIVDADVTKIVPLDPEATIFQLCETIRKNIREAQTKSPKSYGLYLPHDDLKKGLWLDNSKTLQHYILKRGDTIEYRNRSRWLHIRTMDGTNKTLKVDDSWTVSELMLTVCTKLGIYNYDEYSLISDKMDFSPGIDKTLSMKRGISINXXXXXXXXXXXXYHTEDGLNWLNPSQSLRQQGIEESEVLLLKRKYFFSDMNVDSRDPIQLSLLYEQLKDAVINGTHPVTLPEAIELAGLQCQVQLGNYSADKFKPGFLDLRECLPKEYQKNPKTVEKKIFNQHSKSKDLSEVEAKEKYCLLCRSFKTYGITFFLVKEKVIGKNKLIPRLLGVNKESVVQVDEKTKEIINTWPLTSIRKWAASFNGFTMDFGEYSPDEYYTAQTDKGERISQLIAGYIDIILKRKKAKDHLGVDADEESIMYEENIAPSKAIIVEHVPKQKRSSVSEEDVVIRKKAHMANSSVRMNSQASDSVCSQDCTDFYQEDINMSRQTSSLGRTQSPSSSLTTNSMHY-RMSDDDIRQKLYIISLQDNLDTIQKYKDQLMIENKGPEIGKDEASQQWIYVNIDNSRQRMADEIGAMNAAVAQVLRSAQGLATIXXXXXXXXXXXXIAKMQNSFSLITVHLPSLMEEIRTAAYYQDQLTDEDV-SGEELIAAAKRLADAFTNLIKAAYPVEDQKRSLNRKEIFDAANAVGEASSDLLQQITEQENCQIELKSERPYSIIMITEEDQLYQEELLRLAKSVANETTNLIKQVKVIAVEAENPSDQKKVVMAATETGLAISQLISTTKIVAPTIEQSVCQEQLIFSIEDVSKAIQVVVESSNKATQSEELQDLTVQAANQVQEALDTLMKHLRXXXXXXXXXXXXXXAYENI----QEXXXXXXXXXXXXXXXRRLAQATTAMISEIQLKAVNEQYKTPEERDKLINAAKQLAEATTVLIDSAKNCTMDKDEMNLRYTLREATERFIVVTYTTECATYIQEQVIDHLLVAARKAATTGTHLINTSLSAA--KKSRASNFKVCNDGRELSNQISNLIVAIKEARRDPKDHLAQLELIAACRDYIDPSEQLSQSNKYMWPTVSDPSLQTALNQSINQSVIATEELKKCVHQADLMCQHLDLSAALEQLKRLEQNLKSIKNSIERENLIPLPDEKSDESAALLIKSVRRSGSAANQFKNDLESRCVVYEQTNGEDSYQNLENLDVAGQKARELSMALDRLVHAARGVAASIEFENQESENNDKNLEKLAQLQIVNNCLEAVKAARDLVIEAKS---SPPDNDQMDRAQQASVRXXXXXXXXXXXXPGQRDLDMLSKHIESKKHQFAENRLPIQQNNNINLSNCRSELTDTTFDFNQAVNELVSAPSFNLVNKGCKKMRMSYDRIVEICNVLVHDPFDESDSALHHLSS------NRDHIANGVMIMSEDCQTLLDKVKKIQCEPDNIIVRKQLQEATKMLLDSINRLLTNISTNLRPGQKECDKTIYRLESMRPILDNPVHPISHKDYFECLDFIIDKTVQPLADSLKNIPAAVKDENNQKFIDSIYHCADSVCMLLEETAQTAYLVGVGDVRSKIGNKGLADHTSFLQIQKEISENCQTICNPDTTARQDSSLMISTAGQIAENSRKLCEASK--TIMISFPNDKIKLSDKTKITLLAVSELMTGVQNLNQNFNEDNRKEVESLSGKVQDNVAELVQLLLSYKFAGDAAIISEEAKESQGPIKAAGITVLDTAIEVIQCSKALISSEANEELFIAYSSSCKDLNDALKHLISTIKESAPGQKECDEXXXXXXXXXXQAYDSKMKIMKHRSRTISRTFESEESYQNILQSALIQMPHCINELSRAGKKEPEQLARIFSRQTQLLESMVNSCICAANQTDLIQNSNIYLEHLITILEASEQLLKAVKKSGGNPKANSVHSQIDEMAQGVIESCEDLLAALDKISFKQGNVNTIVETITKSSAKVQESAIIPEKSRFGNSQSKMLDICYDMNNLTTDISSNANSESTQRLLAPLTQNLTQRYDDLCRACQGAVATLSNENNGKQLQECVQTVGKVSISLVK--STTEVRPSVASSISNLQAKTQELHKRIDDVIQLLISSNVGTQACTQAIKILKEINSDIDTSILFVKSADIQNDDREYYSVKELFKKSRNSVIDNSSELVRNIKLIVSKDVCDVNILQESADQIAITSQSLANDVKVGLEHLNSSTSQYNIELLVSFQEVIVSLISFLEVARNTSGLPYTDPLFQNLKEEGKCSINAITSLLKVLKSMDDVNLKDFQAIDNAI 6828
L+I + +V K + +P ++ C IR+ + EAQT YGL+L +D +KG+WL+ +TL +Y+L+ GD +EY+ + R IR +DG+ KT+ VDDS TV EL++T+C+++GI NY+EYSLI + ++ + T ++K+ ++ +D+ K++KLK K HT+D LNWL+ S++ R+QG++E+E LLL+RK+F+SD NVDSRDP+QL+LLY Q +D ++NG+HPV+ +A E G Q Q+Q G + K KPGFLDL+E LPKEY K + EK+IF +H ++SE+EAK KY L RS +TYG++FFLVKEK+ GKNKL+PRLLG+ K+SV++VDEKTKE++ WPLT++++WAAS FT+DFGEY + YY+ QT +GE+ISQLIAGYIDIILK+K++KD G++ DEES M EE+++P K+ I++ + R+ +E V + SS +T ++G SP + MH M Q+ + ++ ++ +Q+ +D L + P +G+D AS+ W+ +D S+ + ++ A+ A A V+ G + + + + + I+ +L + + ++ A L D+DV SGE+L+ AA+ LA A ++L+KA P + R + + AA ++G+AS DLL+QI E E D+ +Q+ L+ LAK+VAN L+ + K +A AE+ Q +V+ AAT+ L+ SQL++ K+V+PTI VCQEQLI + + V ++++ V + AT EL AA+ V +AL L++H+R+ + + + + A + I + + S D ++V AR LAQAT+ +++ ++ A E E KL+ AAK LA++T ++++AK + + + + LREA E V T I++++++ L VAA++AA T I S +AA K+ ++ ++ + +++ I L+ ++ ++ +D AQL LI + ++++ P ++ S K PTVSD + L+Q + EL+ +A C +++ +AL ++ L+ L+ K + L PLP E ++ A L + + GS+ Q C G + Y G ARE + AL L AARGVAAS ND A ++++ + ++ + L+ EAK +P D + R Q + +S +L+ C++ LPGQ+D+D+ K I + + LP + +SEL D NQ+ E+V A + S D FDE A ++ ++ + + +S LL K + +P + L A + + +SIN+L+ + T PGQKECD + LE+++ +L+NP P+S YF+C++ +++ + + L +S+ I K + F + + + ++C L E AQ AYLVG+ D S+ G++GL D F + + I CQ + +P ++ Q ++S A +A+++ LC A + + + P K K + + L+ ++ L+ +F+EDNR + + + + V L + +FA A IS E ++Q PI + T+L+++ +I+ +++L + + + + ++D++K LI++I++ APGQ+ECD ++ + + I+ + + + T R S E+ Q L S + ++ H I+ ++ A + E QL ++ E ++ + + A++ Q L+ T+ E++ Q+L A K+ GGNPKA H I E AQ + E+ +D++ L++ + + G V +V+ I ++ +K+ E K F + Q+ ++ Y T S + L L +T Y L Q A AT E G Q++ VQ +G I LV+ +V P+ + + L + + +++ V+ L + N GTQAC A + I +D+DT+I+F + + ++ E F R +++ + LV + KL+VS + L ++A A T LA VK+G L S+ + + L+ + ++V +L + + + P DP LK K + +TSLLK +K+++D + +A++ I
Sbjct: 4 LSLKICVRHCNVVKTMQFEPSTAVYDACRVIRERVPEAQTGQASDYGLFLSDEDPRKGIWLEAGRTLDYYMLRNGDILEYKKKQRPQKIRMLDGSVKTVMVDDSKTVGELLVTICSRIGITNYEEYSLIQETIE-EKKEEGTGTLKKDRTLLRDERKMEKLKAKLHTDDDLNWLDHSRTFREQGVDENETLLLRRKFFYSDQNVDSRDPVQLNLLYVQARDDILNGSHPVSFEKACEFGGFQAQIQFGPHVEHKHKPGFLDLKEFLPKEYIKQ-RGAEKRIFQEHKNCGEMSEIEAKVKYVKLARSLRTYGVSFFLVKEKMKGKNKLVPRLLGITKDSVMRVDEKTKEVLQEWPLTTVKRWAASPKSFTLDFGEYQ-ESYYSVQTTEGEQISQLIAGYIDIILKKKQSKDRFGLEGDEESTMLEESVSPKKSTILQQ--QFNRTGKAEHGSVALPAVMRSGSS--------------------------GPETFNVGSMPSPQQQVMVGQMHRGHMPPLTSAQQALMGTINTSMHAVQQAQDDLSELDSLPPLGQDMASRVWVQNKVDESKHEIHSQVDAITAGTASVVNLTAG----------DPADTDYTAVGCAITTISSNLTEMSKGVKLLAA----LMDDDVGSGEDLLRAARTLAGAVSDLLKAVQPTSGEPR----QTVLTAAGSIGQASGDLLRQIGENET-------------------DERFQDVLMSLAKAVANAAAMLVLKAKNVAQVAEDTVLQNRVIAAATQCALSTSQLVACAKVVSPTISSPVCQEQLIEAGKLVDRSVENCVRACQAATSDSELLKQVSAAASVVSQALHDLLQHVRQFASRGEPIGRYDQATDTIMCVTESIFSSMGDAGEMVRQARVLAQATSDLVNAMRSDA--EAEIDMENSKKLLAAAKLLADSTARMVEAAKGAAANPENEDQQQRLREAAEGLRVAT-NAAAQNAIKKKIVNRLEVAAKQAAAAATQTIAASQNAAISNKNPSAQQQLVQSCKAVADHIPQLVQGVRGSQAQAEDLSAQLALIISSQNFLQPGSKMVSSAKAAVPTVSDQAAAMQLSQCAKNLATSLAELRTASQKAHEACGPMEIDSALNTVQTLKNELQDAKMAAAESQLKPLPGETLEKCAQDLGSTSKGVGSSMAQLLT-----CAA----QGNEHY--------TGVAARETAQALKTLAQAARGVAAS---------TNDPE----AAHAMLDSARDVMEGSAMLIQEAKQALIAPGDTESQQRLAQVAKAVSHSLNNCVNCLPGQKDVDVALKSIGEASKKLLVDSLP---PSTKPFQEAQSELNQAAADLNQSAGEVVHATRGQSGELAAASGKFS-------------DDFDEFLDAGIEMAGQAQTKEDQMQVIGNLKNISMASSKLLLAAKSLSVDPGAPNAKNLLAAAARAVTESINQLIM-LCTQQAPGQKECDNALRELETVKGMLENPNEPVSDLSYFDCIESVMENS-KVLGESMAGISQNAKTGDLPAFGECVGIASKALCGLTEAAAQAAYLVGISDPNSQAGHQGLVDPIQFARANQAIQMACQNLVDPGSSPSQ----VLSAATIVAKHTSALCNACRIASSKTANPVAKRHFVQSAKEVANSTANLVKTIKALDGDFSEDNRNKCRIATTPLIEAVENLTAFASNPEFASIPAQISSEGSQAQEPILVSAKTMLESSSYLIRTARSLAINPKDPPTWSVLAGHSHTVSDSIKSLITSIRDKAPGQRECDYSIDGINRCIRDIEQASLAAVSQSLAT--RDDISVEALQEQLTSVVQEIGHLIDPIATAARGEAAQLGHKVTQLASYFEPLILAAVGVASKMLDHQQQMTVLDQTKTLAESALQMLYAAKEGGGNPKAQHTHDAITEAAQLMKEAVDDIMVTLNEAASEVGLVGGMVDAIAEAMSKLDEGTPPEPKGTFVDYQTTVVK--YSKAIAVTAQEMMTKSVTNPEELGGLASQMTTDYGHLALQGQMAAATAEPEEIGFQIRTRVQDLGHGCIFLVQKAGALQVCPTDSYTKRELIECARSVTEKVSLVLSALQAGNKGTQACITAATAVSGIIADLDTTIMFATAGTLNAEN------GETFADHRENILKTAKALVEDTKLLVSGAASTPDKLAQAAQSSAATITQLAEVVKLGAASLGSNDPETQVVLINAIKDVAKALSDLIGATKGAASKPADDPSMYQLKGAAKVMVTNVTSLLKTVKAVEDEATRGTRALEATI 2151
BLAST of Talin-1 vs. Ensembl Mouse
Match: Tln2 (talin 2 [Source:MGI Symbol;Acc:MGI:1917799]) HSP 1 Score: 932.939 bits (2410), Expect = 0.000e+0 Identity = 692/2281 (30.34%), Postives = 1187/2281 (52.04%), Query Frame = 1
Query: 49 FELRIHIVDADVTKIVPLDPEATIFQLCETIRKNIREAQTKSPKSYGLYLPHDDLKKGLWLDNSKTLQHYILKRGDTIEYRNRSRWLHIRTMDGTNKTLKVDDSWTVSELMLTVCTKLGIYNYDEYSLISDKMDFSPGIDKTLSMKRGISINXXXXXXXXXXXXYHTEDGLNWLNPSQSLRQQGIEESEVLLLKRKYFFSDMNVDSRDPIQLSLLYEQLKDAVINGTHPVTLPEAIELAGLQCQVQLGNYSADKFKPGFLDLRECLPKEYQKNPKTVEKKIFNQHSKSKDLSEVEAKEKYCLLCRSFKTYGITFFLVKEKVIGKNKLIPRLLGVNKESVVQVDEKTKEIINTWPLTSIRKWAASFNGFTMDFGEYSPDEYYTAQTDKGERISQLIAGYIDIILKRKKAKDHLGVDADEESIMYEENIAPSKAIIVEHVPKQKRSSVSEEDVVIRKKAHMANSSVRMNSQASDSVCSQDCTDFYQEDINMSRQTSSLGRTQSPSSSLTTNSMHY-RMSDDDIRQKLYIISLQDNLDTIQKYKDQLMIENKGPEIGKDEASQQWIYVNIDNSRQRMADEIGAMNAAVAQVLRSAQGLATIXXXXXXXXXXXXIAKMQNSFSLITVHLPSLMEEIRTAAYYQDQLTDEDV-SGEELIAAAKRLADAFTNLIKAAYPVEDQKRSLNRKEIFDAANAVGEASSDLLQQITEQENCQIELKSERPYSIIMITEEDQLYQEELLRLAKSVANETTNLIKQVKVIAVEAENPSDQKKVVMAATETGLAISQLISTTKIVAPTIEQSVCQEQLIFSIEDVSKAIQVVVESSNKATQSEELQDLTVQAANQVQEALDTLMKHLRXXXXXXXXXXXXXXAYENI----QEXXXXXXXXXXXXXXXRRLAQATTAMISEIQLKAVNEQYKTPEERDKLINAAKQLAEATTVLIDSAKNCTMDKDEMNLRYTLREATERFIVVTYTTECATYIQEQVIDHLLVAARKAATTGTHLINTSLSAA--KKSRASNFKVCNDGRELSNQISNLIVAIKEARRDPKDHLAQLELIAACRDYIDPSEQLSQSNKYMWPTVSDPSLQTALNQSINQSVIATEELKKCVHQADLMCQHLDLSAALEQLKRLEQNLKSIKNSIERENLIPLPDEKSDESAALLIKSVRRSGSAANQFKNDLESRCVVYEQTNGEDSYQNLENLDVAGQKARELSMALDRLVHAARGVAASIEFENQESENNDKNLEKLAQLQIVNNCLEAVKAARDLVIEAKS---SPPDNDQMDRAQQASVRXXXXXXXXXXXXPGQRDLDMLSKHIESKKHQFAENRLPIQQNNNINLSNCRSELTDTTFDFNQAVNELVSAPSFNLVNKGCKKMRMSYDRIVEICNVLVHDPFDESDSALHHLSS------NRDHIANGVMIMSEDCQTLLDKVKKIQCEPDNIIVRKQLQEATKMLLDSINRLLTNISTNLRPGQKECDKTIYRLESMRPILDNPVHPISHKDYFECLDFIIDKTVQPLADSLKNIPAAVKDENNQKFIDSIYHCADSVCMLLEETAQTAYLVGVGDVRSKIGNKGLADHTSFLQIQKEISENCQTICNPDTTARQDSSLMISTAGQIAENSRKLCEASK--TIMISFPNDKIKLSDKTKITLLAVSELMTGVQNLNQNFNEDNRKEVESLSGKVQDNVAELVQLLLSYKFAGDAAIISEEAKESQGPIKAAGITVLDTAIEVIQCSKALISSEANEELFIAYSSSCKDLNDALKHLISTIKESAPGQKECDEXXXXXXXXXXQAYDSKMKIMKHRSRTISRTFESEESYQNILQSALIQMPHCINELSRAGKKEPEQLARIFSRQTQLLESMVNSCICAANQTDLIQNSNIYLEHLITILEASEQLLKAVKKSGGNPKANSVHSQIDEMAQGVIESCEDLLAALDKISFKQGNVNTIVETITKSSAKVQESAIIPEKSRFGNSQSKMLDICYDMNNLTTDISSNANSESTQRLLAPLTQNLTQRYDDLCRACQGAVATLSNENNGKQLQECVQTVGKVSISLVK--STTEVRPSVASSISNLQAKTQELHKRIDDVIQLLISSNVGTQACTQAIKILKEINSDIDTSILFVKSADIQNDDREYYSVKELFKKSRNSVIDNSSELVRNIKLIVSKDVCDVNILQESADQIAITSQSLANDVKVGLEHLNSSTSQYNIELLVSFQEVIVSLISFLEVARNTSGLPYTDPLFQNLKEEGKCSINAITSLLKVLKSMDDVNLKDFQAIDNAI 6828
L+I + +V K + +P ++ C IR+ + EAQT YGL+L +D +KG+WL+ +TL +Y+L+ GD +EY+ + R IR +DG+ KT+ VDDS TV EL++T+C+++GI NY+EYSLI + ++ + T ++K+ ++ +D+ K++KLK K HT+D LNWL+ S++ R+QG++E+E LLL+RK+F+SD NVDSRDP+QL+LLY Q +D ++NG+HPV+ +A E G Q Q+Q G + K KPGFLDL+E LPKEY K + EK+IF +H ++SE+EAK KY L RS +TYG++FFLVKEK+ GKNKL+PRLLG+ K+SV++VDEKTKE++ WPLT++++WAAS FT+DFGEY + YY+ QT +GE+ISQLIAGYIDIILK+K++KD G++ DEES M EE+++P K+ I++ + R+ +E V + SS +T ++G SP + MH M Q+ + ++ ++ +Q+ +D L + P +G+D AS+ W+ +D S+ + ++ A+ A A V+ G + + + + + I+ +L + + ++ A L D+DV SGE+L+ AA+ LA A ++L+KA P + R + + AA ++G+AS DLL+QI E E D+ +Q+ L+ LAK+VAN L+ + K +A AE+ Q +V+ AAT+ L+ SQL++ K+V+PTI VCQEQLI + + V ++++ V + AT EL AA+ V +AL L++H+R+ + + + + A + I + + S D ++V AR LAQAT+ +++ ++ A E E KL+ AAK LA++T ++++AK + + + + LREA E V T I++++++ L VAA++AA T I S +AA K+ ++ ++ + +++ I L+ ++ ++ +D AQL LI + ++++ P ++ S K PTVSD + L+Q + EL+ +A C +++ +AL ++ L+ L+ K + L PLP E ++ A L + + GS+ Q C G + Y G ARE + AL L AARGVAAS ND A ++++ + ++ + L+ EAK +P D + R Q + +S +L+ C++ LPGQ+D+D+ K I + + LP + +SEL D NQ+ E+V A + S D FDE A ++ ++ + + +S LL K + +P + L A + + +SIN+L+ + T PGQKECD + LE+++ +L+NP P+S YF+C++ +++ + + L +S+ I K + F + + + ++C L E AQ AYLVG+ D S+ G++GL D F + + I CQ + +P ++ Q ++S A +A+++ LC A + + + P K K + + L+ ++ L+ +F+EDNR + + + + V L + +FA A IS E ++Q PI + T+L+++ +I+ +++L + + + + ++D++K LI++I++ APGQ+ECD ++ + + I+ + + + T R S E+ Q L S + ++ H I+ ++ A + E QL ++ E ++ + + A++ Q L+ T+ E++ Q+L A K+ GGNPKA H I E AQ + E+ +D++ L++ + + G V +V+ I ++ +K+ E K F + Q+ ++ Y T S + L L +T Y L Q A AT E G Q++ VQ +G I LV+ +V P+ + + L + + +++ V+ L + N GTQAC A + I +D+DT+I+F + + ++ E F R +++ + LV + KL+VS + L ++A A T LA VK+G L S+ + + L+ + ++V +L + + + P DP LK K + +TSLLK +K+++D + +A++ I
Sbjct: 4 LSLKICVRHCNVVKTMQFEPSTAVYDACRVIRERVPEAQTGQASDYGLFLSDEDPRKGIWLEAGRTLDYYMLRNGDILEYKKKQRPQKIRMLDGSVKTVMVDDSKTVGELLVTICSRIGITNYEEYSLIQETIE-EKKEEGTGTLKKDRTLLRDERKMEKLKAKLHTDDDLNWLDHSRTFREQGVDENETLLLRRKFFYSDQNVDSRDPVQLNLLYVQARDDILNGSHPVSFEKACEFGGFQAQIQFGPHVEHKHKPGFLDLKEFLPKEYIKQ-RGAEKRIFQEHKNCGEMSEIEAKVKYVKLARSLRTYGVSFFLVKEKMKGKNKLVPRLLGITKDSVMRVDEKTKEVLQEWPLTTVKRWAASPKSFTLDFGEYQ-ESYYSVQTTEGEQISQLIAGYIDIILKKKQSKDRFGLEGDEESTMLEESVSPKKSTILQQ--QFNRTGKAEHGSVALPAVMRSGSS--------------------------GPETFNVGSMPSPQQQVMVGQMHRGHMPPLTSAQQALMGTINTSMHAVQQAQDDLSELDSLPPLGQDMASRVWVQNKVDESKHEIHSQVDAITAGTASVVNLTAG----------DPADTDYTAVGCAITTISSNLTEMSKGVKLLAA----LMDDDVGSGEDLLRAARTLAGAVSDLLKAVQPTSGEPR----QTVLTAAGSIGQASGDLLRQIGENET-------------------DERFQDVLMSLAKAVANAAAMLVLKAKNVAQVAEDTVLQNRVIAAATQCALSTSQLVACAKVVSPTISSPVCQEQLIEAGKLVDRSVENCVRACQAATSDSELLKQVSAAASVVSQALHDLLQHVRQFASRGEPIGRYDQATDTIMCVTESIFSSMGDAGEMVRQARVLAQATSDLVNAMRSDA--EAEIDMENSKKLLAAAKLLADSTARMVEAAKGAAANPENEDQQQRLREAAEGLRVAT-NAAAQNAIKKKIVNRLEVAAKQAAAAATQTIAASQNAAISNKNPSAQQQLVQSCKAVADHIPQLVQGVRGSQAQAEDLSAQLALIISSQNFLQPGSKMVSSAKAAVPTVSDQAAAMQLSQCAKNLATSLAELRTASQKAHEACGPMEIDSALNTVQTLKNELQDAKMAAAESQLKPLPGETLEKCAQDLGSTSKGVGSSMAQLLT-----CAA----QGNEHY--------TGVAARETAQALKTLAQAARGVAAS---------TNDPE----AAHAMLDSARDVMEGSAMLIQEAKQALIAPGDTESQQRLAQVAKAVSHSLNNCVNCLPGQKDVDVALKSIGEASKKLLVDSLP---PSTKPFQEAQSELNQAAADLNQSAGEVVHATRGQSGELAAASGKFS-------------DDFDEFLDAGIEMAGQAQTKEDQMQVIGNLKNISMASSKLLLAAKSLSVDPGAPNAKNLLAAAARAVTESINQLIM-LCTQQAPGQKECDNALRELETVKGMLENPNEPVSDLSYFDCIESVMENS-KVLGESMAGISQNAKTGDLPAFGECVGIASKALCGLTEAAAQAAYLVGISDPNSQAGHQGLVDPIQFARANQAIQMACQNLVDPGSSPSQ----VLSAATIVAKHTSALCNACRIASSKTANPVAKRHFVQSAKEVANSTANLVKTIKALDGDFSEDNRNKCRIATTPLIEAVENLTAFASNPEFASIPAQISSEGSQAQEPILVSAKTMLESSSYLIRTARSLAINPKDPPTWSVLAGHSHTVSDSIKSLITSIRDKAPGQRECDYSIDGINRCIRDIEQASLAAVSQSLAT--RDDISVEALQEQLTSVVQEIGHLIDPIATAARGEAAQLGHKVTQLASYFEPLILAAVGVASKMLDHQQQMTVLDQTKTLAESALQMLYAAKEGGGNPKAQHTHDAITEAAQLMKEAVDDIMVTLNEAASEVGLVGGMVDAIAEAMSKLDEGTPPEPKGTFVDYQTTVVK--YSKAIAVTAQEMMTKSVTNPEELGGLASQMTTDYGHLALQGQMAAATAEPEEIGFQIRTRVQDLGHGCIFLVQKAGALQVCPTDSYTKRELIECARSVTEKVSLVLSALQAGNKGTQACITAATAVSGIIADLDTTIMFATAGTLNAEN------GETFADHRENILKTAKALVEDTKLLVSGAASTPDKLAQAAQSSAATITQLAEVVKLGAASLGSNDPETQVVLINAIKDVAKALSDLIGATKGAASKPADDPSMYQLKGAAKVMVTNVTSLLKTVKAVEDEATRGTRALEATI 2151
BLAST of Talin-1 vs. Ensembl Mouse
Match: Mast4 (microtubule associated serine/threonine kinase family member 4 [Source:MGI Symbol;Acc:MGI:1918885]) HSP 1 Score: 648.662 bits (1672), Expect = 0.000e+0 Identity = 313/555 (56.40%), Postives = 400/555 (72.07%), Query Frame = 1
Query: 9565 IKPRSQSLNPCRSPGAYEQDIFILNHVYKERFPKATIQMMERLSAMLEELENENTVSW-EPISRLVHTQIMKHVKDILNMTNLEAITSTYFFELTQNLEKLLKETRLKCPES-LARVRPIVQHLLFIIARPARLLECIEFDPKEFYKLLEVAENNLR---NVQTDVPKYIISKLGLDKDPYDIGSEELNTSLELNGGSLEIXXXXXXXXXXXXXXXXXLNMSQESNNSLELSFSKSMTPKESDFEDIKLISNGAYGAVHLVREKKTKKRFAMKKIRKDNLLLRNQVEQIFAERDIMTFADSPFVVGLYCTFETRKYLCMIMEYVEGGDVATLIKSIGPLPDELARMYFAETVLALEYLHNFGIVHRDLKPDNLLITLEGHIKLTDFGLSKVGLMNLTTTLLESVLNKDCTMFQDKQVFGTPDYIAPEVILRQGYDKMIDWWAMGIILYEFIVGCTPFYGDSTEELFGNIISGEIEWPQDPDPCVPDNAVNLITELLKRDPLVRLGAEGTHEVKEHEFFSDVDWQGLLRQKALFIPVLDHEDDTSYFDPRTSRYQH 11214
++PRS+SL+P RSP + +I ++NHVYKERFPKAT QM ERL ++ ++ + + + H QI++ +D L+ ++ ITS YFFEL L+KLL+E + LA ++ +V+ +L +IARPARLLEC+EFDP+EFY LLE AE + + ++TD+P+YIIS+LGL+KDP EE+ + + E S SN SL L P+ESDFE IKLISNGAYGAV+ VR K++++RFAMKKI K NL+LRNQ++Q F ERDI+TFA++PFVV +YC+FETR++LCM+MEYVEGGD ATL+K++GPLP ++ARMYFAETVLALEYLHN+GIVHRDLKPDNLL+T GHIKLTDFGLSKVGLM++TT L E + KD F DKQV GTP+YIAPEVILRQGY K +DWWAMGIILYEF+VGC PF+GD+ EELFG +IS EI WP+ D P +A LIT LL+++PL RLG G +EVK+H FF +DW LLRQKA FIP L+ EDDTSYFD R+ +Y H
Sbjct: 173 MRPRSRSLSPGRSPACCDHEIIMMNHVYKERFPKATAQMEERLKEIITSYSPDHVLPLADGVLSFTHHQIIELARDCLDKSHQGLITSRYFFELQHKLDKLLQEAHDRSESGELAFIKQLVRKILIVIARPARLLECLEFDPEEFYYLLEAAEGHAKEGQGIKTDIPRYIISQLGLNKDPL----EEMAQLGNYDSRTAETPEMDESVSS--------------SNTSLRLR----RKPRESDFETIKLISNGAYGAVYFVRHKESRQRFAMKKINKQNLILRNQIQQAFVERDILTFAENPFVVSMYCSFETRRHLCMVMEYVEGGDCATLMKNMGPLPVDMARMYFAETVLALEYLHNYGIVHRDLKPDNLLVTSMGHIKLTDFGLSKVGLMSMTTNLYEGHIEKDAREFLDKQVCGTPEYIAPEVILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVISDEINWPEK-DEAPPPDAQELITLLLRQNPLERLGTGGAYEVKQHRFFRSLDWNSLLRQKAEFIPQLESEDDTSYFDTRSEKYHH 704 HSP 2 Score: 111.694 bits (278), Expect = 2.180e-23 Identity = 48/99 (48.48%), Postives = 70/99 (70.71%), Query Frame = 1
Query: 12130 IVIHRRSRNFGFVIRAIRVFYGESNVYTLHHLIVGVDPEGSAFQAGLREGDLITHINGVSIVGAYHTEVVSMIIQSGASISLRVIPINKSFIRTDGPWR 12426
IVIH +N+GF IRAIRV+ G+S++YT+HH++ V+ A+QAGL+ GDLITHING + G HTEV+ ++++SG +S+ P + I+T GP R
Sbjct: 966 IVIHSSGKNYGFTIRAIRVYVGDSDIYTVHHIVWNVEEGSPAYQAGLKAGDLITHINGEPVHGLVHTEVIELLLKSGNKVSITTTPFENTSIKT-GPAR 1063
BLAST of Talin-1 vs. UniProt/SwissProt
Match: sp|Q9Y490|TLN1_HUMAN (Talin-1 OS=Homo sapiens OX=9606 GN=TLN1 PE=1 SV=3) HSP 1 Score: 970.689 bits (2508), Expect = 0.000e+0 Identity = 725/2432 (29.81%), Postives = 1223/2432 (50.29%), Query Frame = 1
Query: 55 LRIHIVDADVTKIVPLDPEATIFQLCETIRKNIREAQTKSPKSYGLYLPHDDLKKGLWLDNSKTLQHYILKRGDTIEYRNRSRWLHIRTMDGTNKTLKVDDSWTVSELMLTVCTKLGIYNYDEYSLISDKMDFSPGIDKTLSMKRGISINXXXXXXXXXXXXYHTEDGLNWLNPSQSLRQQGIEESEVLLLKRKYFFSDMNVDSRDPIQLSLLYEQLKDAVINGTHPVTLPEAIELAGLQCQVQLGNYSADKFKPGFLDLRECLPKEYQKNPKTVEKKIFNQHSKSKDLSEVEAKEKYCLLCRSFKTYGITFFLVKEKVIGKNKLIPRLLGVNKESVVQVDEKTKEIINTWPLTSIRKWAASFNGFTMDFGEYSPDEYYTAQTDKGERISQLIAGYIDIILKRKKAKDHLGVDADEESIMYEENIAPSKAIIVEH----VPKQKRSSVSEEDVVIRKKAHMANSSVRMNSQASDSVCSQDCTDFYQEDINMSRQTSSLGRTQSPSSSLTTNSMHY-RMSDDDIRQKLYIISLQDNLDTIQKYKDQLMIENKGPEIGKDEASQQWIYVNIDNSRQRMADEIGAMNAAVAQVLRSAQGLATIXXXXXXXXXXXXIAKMQNSFSLITVHLPSLMEEIRTAAYYQDQLTDEDVSGEELIAAAKRLADAFTNLIKAAYPVEDQKRSLNRKEIFDAANAVGEASSDLLQQITEQENCQIELKSERPYSIIMITEEDQLYQEELLRLAKSVANETTNLIKQVKVIAVEAENPSDQKKVVMAATETGLAISQLISTTKIVAPTIEQSVCQEQLIFSIEDVSKAIQVVVESSNKATQSEELQDLTVQAANQVQEALDTLMKHLRXXXXXXXXXXXXXXAYENI----QEXXXXXXXXXXXXXXXRRLAQATTAMISEIQLKAVNEQYKTPEERDKLINAAKQLAEATTVLIDSAKNCTMDKDEMNLRYTLREATERFIVVTYTTECATYIQEQVIDHLLVAARKAATTGTHLINTSLSAAKKSRASNFK---VCNDGRELSNQISNLIVAIKEARRDPKDHLAQLELIAACRDYIDPSEQLSQSNKYMWPTVSDPSLQTALNQSINQSVIATEELKKCVHQADLMCQHLDLSAALEQLKRLEQNLKSIKNSIERENLIPLPDEKSDESAALLIKSVRRSGSAANQFKNDLESRCVVYEQTNGEDSYQNLENLDVAGQKARELSMALDRLVHAARGVAASIEFENQESENNDKNLEKLAQLQIVNNCLEAVKAARDLVIEAKSS---PPDNDQMDRAQQASVRXXXXXXXXXXXXPGQRDLDMLSKHIESKKHQFAENRLPIQQNNNINLSNCRSELTDTTFDFNQAVNELVSAPSFNLVNKGCKK-MRMSYDRIVEICNVLVHDPFDESDSALHHLSSNRDHIANGVMIMSEDCQTLLDKVKKIQCEPDNIIVRKQLQEATKMLLDSINRLLTNISTNLRPGQKECDKTIYRLESMRPILDNPVHPISHKDYFECLDFIIDKTVQPLADSLKNIPAAVKDENNQKFIDSIYHCADSVCMLLEETAQTAYLVGVGDVRSKIGNKGLADHTSFLQIQKEISENCQTICNPDTTARQDSSLMISTAGQIAENSRKLCEASK--TIMISFPNDKIKLSDKTKITLLAVSELMTGVQNLNQNFNEDNRKEVESLSGKVQDNVAELVQLLLSYKFAGDAAIISEEAKESQGPIKAAGITVLDTAIEVIQCSKALISSEANEELFIAYSSSCKDLNDALKHLISTIKESAPGQKECDEXXXXXXXXXXQAYDSKMKIMKHRS------RTISRTFESEESYQNILQSALIQMPHCINELSRAGKKEPEQLARIFSRQTQLLESMVNSCICAANQTDLIQNSNIYLEHLITILEASEQLLKAVKKSGGNPKANSVHSQ--IDEMAQGVIESCEDLLAALDKISFKQGNVNTIVETITKSSAKVQESAIIPEKSRFGNSQSKMLDICYDMNNLTTDISSNANSESTQRLLAPLTQNLTQRYDDLCRACQGAVATLSNENNGKQLQECVQTVGKVSISLVKSTTEVR--PSVASSISNLQAKTQELHKRIDDVIQLLISSNVGTQACTQAIKILKEINSDIDTSILFVKSADIQNDDREYYSVKELFKKSRNSVIDNSSELVRNIKLIVSKDVCDVNILQESADQIAITSQSLANDVKVGLEHLNSSTSQYNIELLVSFQEVIVSLISFLEVARNTSGLPYTDPLFQNLKEEGKCSINAITSLLKVLKSMDDVNLKDFQAIDNAIIXXXXXXXXXXXXXXGISREASPVESPTSTNRLSIGSDITVSPRFAPEEINRLIPSLANVCDKILEISSPEFKPIIRQENISVVSISCSKVNNELTSACKNLLRNGPVT-DSKKQTLNTVDQLVENYTELLKNFKLYLTNPTKETR 7263
L + I +V K + +P ++ C IR+ I EA P +GL+L DD KKG+WL+ K L +Y+L+ GDT+EYR + R L IR +DGT KT+ VDDS TV+++++T+C ++GI N+DEYSL+ + M+ + T ++++ ++ +D++K++KLK+K HT+D LNWL+ ++LR+QG+EE E LLL+RK+F+SD NVDSRDP+QL+LLY Q +D ++NG+HPV+ +A E AG QCQ+Q G ++ K K GFLDL++ LPKEY K + E+KIF H +SE+EAK +Y L RS KTYG++FFLVKEK+ GKNKL+PRLLG+ KE V++VDEKTKE+I W LT+I++WAAS FT+DFG+Y D YY+ QT +GE+I+QLIAGYIDIILK+KK+KDH G++ DEES M E++++P K+ +++ V K + SV+ + M S AS + +Q +G +T+ MH M Q+ ++ ++ +Q + L + P +G+D AS+ W +D S+ + ++ A+ A A V+ G + E + + + I+ +L + ++ A L DE SG L+ AAK LA A + L+++A P + R + + AA VG+AS +LLQQI E ++ D +Q+ L++LAK+VA+ L+ + K +A E+ Q +V+ AAT+ L+ SQL++ TK+VAPTI VCQEQL+ + V+KA++ V +S AT+ +L AA V +AL+ L++H++ + A + I + + S D ++V AR LAQAT+ +++ I KA E E KL++AAK LA+AT ++++AK D + LREA E + T I+++++ L AA++AA + T I + AA +AS + + ++ QI L+ ++ ++ P AQL LIAA + ++ P ++ + K PT+ D + L+Q A EL+ +A C L++ +AL ++ LE++L+ +K + L PLP E ++ L S + SA Q + E G ++Y + DVAG L L AARGVAA +D ++ + +++ + + A L+ EAK + P D + R Q + ++ AL+ C+ LPGQRD+D + + + + LP + +S L + NQA ELV A ++G + + + R + + + + + A +R + + + +S LL K + +P ++ QL A + + DSIN+L+T + T PGQKECD + LE++R +L+NPV PI+ YF CLD +++ + + L +++ I K+ N +F D+I + ++C E AQ AYLVGV D S+ G +GL + T F + + I CQ++ P T Q ++S A +A+++ LC + + + + P K + K + + L+ ++ L+ F E+NR + + + + + V L + +F+ A IS E + + PI + T+L++A +IQ ++AL + + + + + ++D++K LI+++++ APGQ EC+ A +S ++ + S + R S+E+ + +A+ ++ H I L+ A + E QL S+ Q E + + + AA++T L+ T+ E++ QLL K++GGNPK + H+Q ++E Q + E+ EDL L++ + G V +V++IT++ ++ E + + F + Q+ M+ + ++ + +N+ + L PL LT Y L + A NE G ++ VQ +G +LV ++ PS A + L + + +++ V+ L + N GTQAC A + I +D+DT+I+F + + +RE E F R ++ + LV + K++V L ++A T LA+ VK+G L + + + L+ + ++V +L + + +G DP LK K + +TSLLK +K+++D K +A++ I +E + SP + S PE+ R+ + K + + RQE++ + + ++ ACK + V D + + L+ + Y ELL + L L P+ E +
Sbjct: 4 LSLKISIGNVVKTMQFEPSTMVYDACRIIRERIPEAPAGPPSDFGLFLSDDDPKKGIWLEAGKALDYYMLRNGDTMEYRKKQRPLKIRMLDGTVKTIMVDDSKTVTDMLMTICARIGITNHDEYSLVRELME-EKKEEITGTLRKDKTLLRDEKKMEKLKQKLHTDDELNWLDHGRTLREQGVEEHETLLLRRKFFYSDQNVDSRDPVQLNLLYVQARDDILNGSHPVSFDKACEFAGFQCQIQFGPHNEQKHKAGFLDLKDFLPKEYVK--QKGERKIFQAHKNCGQMSEIEAKVRYVKLARSLKTYGVSFFLVKEKMKGKNKLVPRLLGITKECVMRVDEKTKEVIQEWNLTNIKRWAASPKSFTLDFGDYQ-DGYYSVQTTEGEQIAQLIAGYIDIILKKKKSKDHFGLEGDEESTMLEDSVSPKKSTVLQQQYNRVGKVEHGSVALPAI--------------MRSGASGP-------ENFQ-----------VGSMPPAQQQITSGQMHRGHMPPLTSAQQALTGTINSSMQAVQAAQATLDDFDTLPPLGQDAASKAWRKNKMDESKHEIHSQVDAITAGTASVVNLTAG----------DPAETDYTAVGCAVTTISSNLTEMSRGVKLLAAL---LEDEGGSGRPLLQAAKGLAGAVSELLRSAQPASAEPR----QNLLQAAGNVGQASGELLQQIGE-------------------SDTDPHFQDALMQLAKAVASAAAALVLKAKSVAQRTEDSGLQTQVIAAATQCALSTSQLVACTKVVAPTISSPVCQEQLVEAGRLVAKAVEGCVSASQAATEDGQLLRGVGAAATAVTQALNELLQHVKAHATGAGPAGRYDQATDTILTVTENIFSSMGDAGEMVRQARILAQATSDLVNAI--KADAEGESDLENSRKLLSAAKILADATAKMVEAAKGAAAHPDSEEQQQRLREAAEGLRMAT-NAAAQNAIKKKLVQRLEHAAKQAAASATQTIAAAQHAASTPKASAGPQPLLVQSCKAVAEQIPLLVQGVRGSQAQPDSPSAQLALIAASQSFLQPGGKMVAAAKASVPTIQDQASAMQLSQCAKNLGTALAELRTAAQKAQEACGPLEMDSALSVVQNLEKDLQEVKAAARDGKLKPLPGETMEKCTQDLGNSTKAVSSAIAQL---------LGEVAQGNENYAGIAARDVAG--------GLRSLAQAARGVAAL---------TSDPAVQAI----VLDTASDVLDKASSLIEEAKKAAGHPGDPESQQRLAQVAKAVTQALNRCVSCLPGQRDVDNALRAVGDASKRLLSDSLP---PSTGTFQEAQSRLNEAAAGLNQAATELVQA------SRGTPQDLARASGRFGQDFSTFLEAGVEMAGQAPSQ--EDRAQVVSNLKGISMSSSKLLLAAKALSTDPAAPNLKSQLAAAARAVTDSINQLIT-MCTQQAPGQKECDNALRELETVRELLENPVQPINDMSYFGCLDSVMENS-KVLGEAMTGISQNAKNGNLPEFGDAISTASKALCGFTEAAAQAAYLVGVSDPNSQAGQQGLVEPTQFARANQAIQMACQSLGEPGCTQAQ----VLSAATIVAKHTSALCNSCRLASARTTNPTAKRQFVQSAKEVANSTANLVKTIKALDGAFTEENRAQCRAATAPLLEAVDNLSAFASNPEFSSIPAQISPEGRAAMEPIVISAKTMLESAGGLIQTARALAVNPRDPPSWSVLAGHSRTVSDSIKKLITSMRDKAPGQLECE--------TAIAALNSCLRDLDQASLAAVSQQLAPREGISQEALHTQMLTAVQEISHLIEPLANAARAEASQLGHKVSQMAQYFEPLTLAAVGAASKTLSHPQQMALLDQTKTLAESALQLLYTAKEAGGNPK-QAAHTQEALEEAVQMMTEAVEDLTTTLNEAASAAGVVGGMVDSITQAINQLDEGPMGEPEGSFVDYQTTMVRTAKAIAVTVQEMVTKSNTSPEE--LGPLANQLTSDYGRLASEAKPAAVAAENEEIGSHIKHRVQELGHGCAALVTKAGALQCSPSDAYTKKELIECARRVSEKVSHVLAALQAGNRGTQACITAASAVSGIIADLDTTIMFATAGTL---NREGT---ETFADHREGILKTAKVLVEDTKVLVQNAAGSQEKLAQAAQSSVATITRLADVVKLGAASLGAEDPETQVVLINAVKDVAKALGDLISATKAAAGKVGDDPAVWQLKNSAKVMVTNVTSLLKTVKAVEDEATKGTRALE--------------ATTEHIRQELAVFCSPEPPAKTST-----------PEDFIRMTKGITMATAKAVAAGNS-----CRQEDVIATANLSRRAIADMLRACKEAAYHPEVAPDVRLRALHYGRECANGYLELLDHVLLTLQKPSPELK 2266
BLAST of Talin-1 vs. UniProt/SwissProt
Match: sp|P26039|TLN1_MOUSE (Talin-1 OS=Mus musculus OX=10090 GN=Tln1 PE=1 SV=2) HSP 1 Score: 962.214 bits (2486), Expect = 0.000e+0 Identity = 696/2283 (30.49%), Postives = 1176/2283 (51.51%), Query Frame = 1
Query: 55 LRIHIVDADVTKIVPLDPEATIFQLCETIRKNIREAQTKSPKSYGLYLPHDDLKKGLWLDNSKTLQHYILKRGDTIEYRNRSRWLHIRTMDGTNKTLKVDDSWTVSELMLTVCTKLGIYNYDEYSLISDKMDFSPGIDKTLSMKRGISINXXXXXXXXXXXXYHTEDGLNWLNPSQSLRQQGIEESEVLLLKRKYFFSDMNVDSRDPIQLSLLYEQLKDAVINGTHPVTLPEAIELAGLQCQVQLGNYSADKFKPGFLDLRECLPKEYQKNPKTVEKKIFNQHSKSKDLSEVEAKEKYCLLCRSFKTYGITFFLVKEKVIGKNKLIPRLLGVNKESVVQVDEKTKEIINTWPLTSIRKWAASFNGFTMDFGEYSPDEYYTAQTDKGERISQLIAGYIDIILKRKKAKDHLGVDADEESIMYEENIAPSKAIIVEH----VPKQKRSSVSEEDVVIRKKAHMANSSVRMNSQASDSVCSQDCTDFYQEDINMSRQTSSLGRTQSPSSSLTTNSMHY-RMSDDDIRQKLYIISLQDNLDTIQKYKDQLMIENKGPEIGKDEASQQWIYVNIDNSRQRMADEIGAMNAAVAQVLRSAQGLATIXXXXXXXXXXXXIAKMQNSFSLITVHLPSLMEEIRTAAYYQDQLTDEDVSGEELIAAAKRLADAFTNLIKAAYPVEDQKRSLNRKEIFDAANAVGEASSDLLQQITEQENCQIELKSERPYSIIMITEEDQLYQEELLRLAKSVANETTNLIKQVKVIAVEAENPSDQKKVVMAATETGLAISQLISTTKIVAPTIEQSVCQEQLIFSIEDVSKAIQVVVESSNKATQSEELQDLTVQAANQVQEALDTLMKHLRXXXXXXXXXXXXXXAYENI----QEXXXXXXXXXXXXXXXRRLAQATTAMISEIQLKAVNEQYKTPEERDKLINAAKQLAEATTVLIDSAKNCTMDKDEMNLRYTLREATERFIVVTYTTECATYIQEQVIDHLLVAARKAATTGTHLINTSLSAAKKSRASNFK---VCNDGRELSNQISNLIVAIKEARRDPKDHLAQLELIAACRDYIDPSEQLSQSNKYMWPTVSDPSLQTALNQSINQSVIATEELKKCVHQADLMCQHLDLSAALEQLKRLEQNLKSIKNSIERENLIPLPDEKSDESAALLIKSVRRSGSAANQFKNDLESRCVVYEQTNGEDSYQNLENLDVAGQKARELSMALDRLVHAARGVAASIEFENQESENNDKNLEKLAQLQIVNNCLEAVKAARDLVIEAKSS---PPDNDQMDRAQQASVRXXXXXXXXXXXXPGQRDLDMLSKHIESKKHQFAENRLPIQQNNNINLSNCRSELTDTTFDFNQAVNELVSAPSFNLVNKGCKK-MRMSYDRIVEICNVLVHDPFDESDSALHHLSSNRDHIANGVMIMSEDCQTLLDKVKKIQCEPDNIIVRKQLQEATKMLLDSINRLLTNISTNLRPGQKECDKTIYRLESMRPILDNPVHPISHKDYFECLDFIIDKTVQPLADSLKNIPAAVKDENNQKFIDSIYHCADSVCMLLEETAQTAYLVGVGDVRSKIGNKGLADHTSFLQIQKEISENCQTICNPDTTARQDSSLMISTAGQIAENSRKLCEASK--TIMISFPNDKIKLSDKTKITLLAVSELMTGVQNLNQNFNEDNRKEVESLSGKVQDNVAELVQLLLSYKFAGDAAIISEEAKESQGPIKAAGITVLDTAIEVIQCSKALISSEANEELFIAYSSSCKDLNDALKHLISTIKESAPGQKECDEXXXXXXXXXXQAYDSKMKIMKHRS------RTISRTFESEESYQNILQSALIQMPHCINELSRAGKKEPEQLARIFSRQTQLLESMVNSCICAANQTDLIQNSNIYLEHLITILEASEQLLKAVKKSGGNPKANSVHSQ--IDEMAQGVIESCEDLLAALDKISFKQGNVNTIVETITKSSAKVQESAIIPEKSRFGNSQSKMLDICYDMNNLTTDISSNANSESTQRLLAPLTQNLTQRYDDLCRACQGAVATLSNENNGKQLQECVQTVGKVSISLVKSTTEVR--PSVASSISNLQAKTQELHKRIDDVIQLLISSNVGTQACTQAIKILKEINSDIDTSILFVKSADIQNDDREYYSVKELFKKSRNSVIDNSSELVRNIKLIVSKDVCDVNILQESADQIAITSQSLANDVKVGLEHLNSSTSQYNIELLVSFQEVIVSLISFLEVARNTSGLPYTDPLFQNLKEEGKCSINAITSLLKVLKSMDDVNLKDFQAID 6819
L + I +V K + +P ++ C IR+ I EA P +GL+L DD KKG+WL+ K L +Y+L+ GDT+EYR + R L IR +DGT KT+ VDDS TV+++++T+C ++GI N+DEYSL+ + M+ + T ++++ ++ +D++K++KLK+K HT+D LNWL+ ++LR+QG+EE E LLL+RK+F+SD NVDSRDP+QL+LLY Q +D ++NG+HPV+ +A E AG QCQ+Q G ++ K K GFLDL++ LPKEY K + E+KIF H +SE+EAK +Y L RS KTYG++FFLVKEK+ GKNKL+PRLLG+ KE V++VDEKTKE+I W LT+I++WAAS FT+DFG+Y D YY+ QT +GE+I+QLIAGYIDIILK+KK+KDH G++ DEES M E++++P K+ +++ V K + SV+ + M S AS + +Q +G +T+ MH M Q+ ++ ++ +Q + L P +G+D AS+ W +D S+ + ++ A+ A A V+ G + E + + + I+ +L + ++ A L DE +G L+ AAK LA A + L+++A P + R + + AA VG+AS +LLQQI E ++ D +Q+ L++LAK+VA+ L+ + K +A E+ Q +V+ AAT+ L+ SQL++ TK+VAPTI VCQEQL+ + V+KA++ V +S AT+ +L AA V +AL+ L++H++ + A + I + + S D ++V AR LAQAT+ +++ I KA E E KL++AAK LA+AT ++++AK D + LREA E + T I+++++ L AA++AA + T I + AA +AS + + ++ QI L+ ++ ++ P AQL LIAA + ++ P ++ + K PT+ D + L+Q A EL+ +A C L++ +AL ++ LE++L+ IK + L PLP E ++ L S + SA + ++ G ++Y + DVAG L L AARGVAA +D ++ + +++ + + A L+ EAK + P D + R Q + ++ AL+ C+ LPGQRD+D + + + + LP + +S L + NQA ELV A ++G + + + R + + + + + A +R + + + +S LL K + +P + ++ QL A + + DSIN+L+T + T PGQKECD + +LE++R +L+NPV PI+ YF CLD +++ + + L +++ I K+ N +F D+I + ++C E AQ AYLVGV D S+ G +GL + T F + + I CQ++ P T Q ++S A +A+++ LC + + + + P K + K + + L+ ++ L+ +F E+NR + + + + + V L + +F+ A IS E + + PI + T+L++A +IQ ++AL + + + + + ++D++K LI+++++ APGQ EC+ A +S ++ + S + R S+E+ + +A+ ++ H I L+ A + E QL S+ Q E + + + AA++T L+ T+ E++ QLL K++GGNPK + H+Q ++E Q + E+ EDL L++ + G V +V++IT++ ++ E + + F + Q+ M+ + ++ + +N+ + L PL LT Y L + A NE G ++ VQ +G +LV ++ PS + L + + +++ V+ L + N GTQAC A + I +D+DT+I+F + + +RE E F R ++ + LV + K++V L ++A T LA+ VK+G L + + + L+ + ++V +L + + +G DP LK K + +TSLLK +K+++D K +A++
Sbjct: 4 LSLKISIGNVVKTMQFEPSTMVYDACRMIRERIPEALAGPPNDFGLFLSDDDPKKGIWLEAGKALDYYMLRNGDTMEYRKKQRPLKIRMLDGTVKTIMVDDSKTVTDMLMTICARIGITNHDEYSLVRELMEEKKD-EGTGTLRKDKTLLRDEKKMEKLKQKLHTDDELNWLDHGRTLREQGVEEHETLLLRRKFFYSDQNVDSRDPVQLNLLYVQARDDILNGSHPVSFDKACEFAGFQCQIQFGPHNEQKHKAGFLDLKDFLPKEYVK--QKGERKIFQAHKNCGQMSEIEAKVRYVKLARSLKTYGVSFFLVKEKMKGKNKLVPRLLGITKECVMRVDEKTKEVIQEWSLTNIKRWAASPKSFTLDFGDYQ-DGYYSVQTTEGEQIAQLIAGYIDIILKKKKSKDHFGLEGDEESTMLEDSVSPKKSTVLQQQYNRVGKVEHGSVALPAI--------------MRSGASGP-------ENFQ-----------VGSMPPAQQQITSGQMHRGHMPPLTSAQQALTGTINSSMQAVQAAQATLDDFETLPPLGQDAASKAWRKNKMDESKHEIHSQVDAITAGTASVVNLTAG----------DPAETDYTAVGCAVTTISSNLTEMSRGVKLLAAL---LEDEGGNGRPLLQAAKGLAGAVSELLRSAQPASAEPR----QNLLQAAGNVGQASGELLQQIGE-------------------SDTDPHFQDVLMQLAKAVASAAAALVLKAKSVAQRTEDSGLQTQVIAAATQCALSTSQLVACTKVVAPTISSPVCQEQLVEAGRLVAKAVEGCVSASQAATEDGQLLRGVGAAATAVTQALNELLQHVKAHATGAGPAGRYDQATDTILTVTENIFSSMGDAGEMVRQARILAQATSDLVNAI--KADAEGESDLENSRKLLSAAKILADATAKMVEAAKGAAAHPDSEEQQQRLREAAEGLRMAT-NAAAQNAIKKKLVQRLEHAAKQAAASATQTIAAAQHAASAPKASAGPQPLLVQSCKAVAEQIPLLVQGVRGSQAQPDSPSAQLALIAASQSFLQPGGKMVAAAKASVPTIQDQASAMQLSQCAKNLGTALAELRTAAQKAQEACGPLEMDSALSVVQNLEKDLQEIKAAARDGKLKPLPGETMEKCTQDLGNSTKAVSSAIAKLLGEI---------AQGNENYAGIAARDVAG--------GLRSLAQAARGVAAL---------TSDPAVQAI----VLDTASDVLDKASSLIEEAKKASGHPGDPESQQRLAQVAKAVTQALNRCVSCLPGQRDVDNALRAVGDASKRLLSDSLP---PSTGTFQEAQSRLNEAAAGLNQAATELVQA------SRGTPQDLARASGRFGQDFSTFLEAGVEMAGQAPSQ--EDRAQVVSNLKGISMSSSKLLLAAKALSTDPASPNLKSQLAAAARAVTDSINQLIT-MCTQQAPGQKECDNALRQLETVRELLENPVQPINDMSYFGCLDSVMENS-KVLGEAMTGISQNAKNGNLPEFGDAIATASKALCGFTEAAAQAAYLVGVSDPNSQAGQQGLVEPTQFARANQAIQMACQSLGEPGCTQAQ----VLSAATIVAKHTSALCNSCRLASARTANPTAKRQFVQSAKEVANSTANLVKTIKALDGDFTEENRAQCRAATAPLLEAVDNLSAFASNPEFSSVPAQISPEGRAAMEPIVISAKTMLESAGGLIQTARALAVNPRDPPRWSVLAGHSRTVSDSIKKLITSMRDKAPGQLECE--------TAIAALNSCLRDLDQASLAAVSQQLAPREGISQEALHTQMLTAVQEISHLIEPLASAARAEASQLGHKVSQMAQYFEPLTLAAVGAASKTLSHPQQMALLDQTKTLAESALQLLYTAKEAGGNPK-QAAHTQEALEEAVQMMTEAVEDLTTTLNEAASAAGVVGGMVDSITQAINQLDEGPMGDPEGSFVDYQTTMVRTAKAIAVTVQEMVTKSNTSPEE--LGPLANQLTSDYGRLASQAKPAAVAAENEEIGAHIKHRVQELGHGCSALVTKAGALQCSPSDVYTKKELIECARRVSEKVSHVLAALQAGNRGTQACITAASAVSGIIADLDTTIMFATAGTL---NREGA---ETFADHREGILKTAKVLVEDTKVLVQNAAGSQEKLAQAAQSSVATITRLADVVKLGAASLGAEDPETQVVLINAVKDVAKALGDLISATKAAAGKVGDDPAVWQLKNSAKVMVTNVTSLLKTVKAVEDEATKGTRALE 2147
BLAST of Talin-1 vs. UniProt/SwissProt
Match: sp|P54939|TLN1_CHICK (Talin-1 OS=Gallus gallus OX=9031 GN=TLN1 PE=1 SV=2) HSP 1 Score: 959.518 bits (2479), Expect = 0.000e+0 Identity = 734/2449 (29.97%), Postives = 1252/2449 (51.12%), Query Frame = 1
Query: 55 LRIHIVDADVTKIVPLDPEATIFQLCETIRKNIREAQTKSPKSYGLYLPHDDLKKGLWLDNSKTLQHYILKRGDTIEYRNRSRWLHIRTMDGTNKTLKVDDSWTVSELMLTVCTKLGIYNYDEYSLISDKMDFSPGIDKTLSMKRGISINXXXXXXXXXXXXYHTEDGLNWLNPSQSLRQQGIEESEVLLLKRKYFFSDMNVDSRDPIQLSLLYEQLKDAVINGTHPVTLPEAIELAGLQCQVQLGNYSADKFKPGFLDLRECLPKEYQKNPKTVEKKIFNQHSKSKDLSEVEAKEKYCLLCRSFKTYGITFFLVKEKVIGKNKLIPRLLGVNKESVVQVDEKTKEIINTWPLTSIRKWAASFNGFTMDFGEYSPDEYYTAQTDKGERISQLIAGYIDIILKRKKAKDHLGVDADEESIMYEENIAPSKAIIVEH----VPKQKRSSVSEEDVVIRKKAHMANSSVRMNSQASDSVCSQDCTDFYQEDINMSRQTSSLGRTQSPSSSLTTNSMHYRMSDDDIRQKLYIISLQDNLDTIQKYKDQLMIENKGPEIGKDEASQQWIYVNIDNSRQRMADEIGAMNAAVAQVLRSAQGLATIXXXXXXXXXXXXIAKMQNSFSLITVHLPSLMEEIRTAAYYQDQLTDEDVSGEELIAAAKRLADAFTNLIKAAYPVEDQKRSLNRKEIFDAANAVGEASSDLLQQITEQENCQIELKSERPYSIIMITEEDQLYQEELLRLAKSVANETTNLIKQVKVIAVEAENPSDQKKVVMAATETGLAISQLISTTKIVAPTIEQSVCQEQLIFSIEDVSKAIQVVVESSNKATQSEELQDLTVQAANQVQEALDTLMKHLRXXXXXXXXXXXXXXAYENI----QEXXXXXXXXXXXXXXXRRLAQATTAMISEIQLKAVNEQYKTPEERDKLINAAKQLAEATTVLIDSAKNCTMDKDEMNLRYTLREATERFIVVTYTTECATYIQEQVIDHLLVAARKAATTGTHLI--NTSLSAAKKSRASNFKVCNDGRELSNQISNLIVAIKEARRDPKDHLAQLELIAACRDYIDPSEQLSQSNKYMWPTVSDPSLQTALNQSINQSVIATEELKKCVHQADLMCQHLDLSAALEQLKRLEQNLKSIKNSIERENLIPLPDEKSDESAALLIKSVRRSGSAANQFKNDLESRCVVYEQTNGEDSYQNLENLDVAGQKARELSMALDRLVHAARGVAASIEFENQESENNDKNLEKLAQLQIVNNCLEAVKAARDLVIEAK---SSPPDNDQMDRAQQASVRXXXXXXXXXXXXPGQRDLDMLSKHIESKKHQFAENRLPIQQNNNINLSNCRSELTDTTFDFNQAVNELVSAPSFNLVNKGCKKMRMSYDRIVEICNVLVHDPFDESDSALHHLSSNRD---HIANGVMIMSEDCQTLLDKVKKIQCEPDNIIVRKQLQEATKMLLDSINRLLTNISTNLRPGQKECDKTIYRLESMRPILDNPVHPISHKDYFECLDFIIDKTVQPLADSLKNIPAAVKDENNQKFIDSIYHCADSVCMLLEETAQTAYLVGVGDVRSKIGNKGLADHTSFLQIQKEISENCQTICNPDTTARQDSSLMISTAGQIAENSRKLCEASK--TIMISFPNDKIKLSDKTKITLLAVSELMTGVQNLNQNFNEDNRKEVESLSGKVQDNVAELVQLLLSYKFAGDAAIISEEAKESQGPIKAAGITVLDTAIEVIQCSKALISSEANEELFIAYSSSCKDLNDALKHLISTIKESAPGQKECDEXXXXXXXXXXQAYDSKMKIMKHRSRTISRTFESEESYQNILQSALIQMPHCINELSRAGKKEPEQLARIFSRQTQLLESMVNSCICAANQTDLIQNSNIYLEHLITILEASEQLLKAVKKSGGNPKANSVHSQ--IDEMAQGVIESCEDLLAALDKISFKQGNVNTIVETITKSSAKVQESAIIPEKSRFGNSQSKMLD----ICYDMNNLTTDISSNANSESTQRLLAPLTQNLTQRYDDLCRACQGAVATLSNENNGKQLQECVQTVGKVSISLVKSTTEVR--PSVASSISNLQAKTQELHKRIDDVIQLLISSNVGTQACTQAIKILKEINSDIDTSILFVKSADIQNDDREYYSVKELFKKSRNSVIDNSSELVRNIKLIVSKDVCDVNILQESADQIAITSQSLANDVKVGLEHLNSSTSQYNIELLVSFQEVIVSLISFLEVARNTSGLPYTDPLFQNLKEEGKCSINAITSLLKVLKSMDDVNLKDFQAIDNAIIXXXXXXXXXXXXXXGISREASPVESPTSTNRLSIGSDITVSPRFAPEEINRLIPSLANVCDKILEISSPEFKPIIRQENISVVSISCSKVNNELTSACKNLLRNGPVT-DSKKQTLNTVDQLVENYTELLKNFKLYLTNPTKETRIPV----ETVVSKLNELIK 7308
L + I +V K + +P ++ C IR+ + EAQ P +GL+L +D KKG+WL+ K L +Y+L+ GDT+EY+ + R L IR +DGT KT+ VDDS TV++++ T+C ++GI NYDEYSL+ + M+ + T ++K+ ++ +D++K++KLK+K HT+D LNWL+ ++LR+QGI+++E LLL+RK+F+SD NVDSRDP+QL+LLY Q +D ++NG+HPV+ +A E AG QCQ+Q G ++ K KPGFL+L++ LPKEY K + E+KIF H ++SE+EAK +Y L RS KTYG++FFLVKEK+ GKNKL+PRLLG+ KE V++VDEKTKE+I W LT+I++WAAS FT+DFG+Y D YY+ QT +GE+I+QLIAGYIDIILK+KK+KDH G++ DEES M E++++P K+ +++ V K + SV+ ++ N V QA + S + + ++Q T +++ M + Q D+ +T+ P +G+D AS+ W +D S+ + + A+ A A V+ G + I+ S L +LME DE +G +L+ AAK LA A ++L+K A P + R + + AA VG+ S +LLQQI E ++ D +Q+ L++LAK+VA+ L+ + K +A + E+ + Q +V+ AAT+ L+ SQL++ TK+VAPTI VCQEQLI + + V+K+ + VE+S AT ++L AA V +AL+ L++H+++ + + A + I + + S D ++V AR LAQAT+ +++ I KA E E KL++AAK LA+AT ++++AK D + LREA E + T I+++++ L AA++AA + T I +A+ K+ A+ ++ + +++QI L+ ++ ++ P AQL LIAA ++++ P ++ + K PT++D + L+Q A EL+ +A C L++ +AL ++ LE++LK K + L PLP E ++ A L S + SA + E G ++Y G ARE++ AL L AARGVAA+ S+ +N A L+ ++ ++ A +L+ EA+ + P D D R Q + +S AL+ C++ LPGQRD+D + + + + P +N +S+L NQ+ NELV A + + D + F ++ + LS ++ + + + +S LL K + +P + ++ QL A + + DSIN+L+T + T PGQKECD + LE+++ +L+NP ++ YF CLD +++ + + L +S+ I K+ +F +SI + ++C L E AQ AYLVGV D S+ G +GL D T F + + I CQ + +P T Q ++S A +A+++ LC + + + P K + K + + L+ ++ L+ FNE+NR+ + + + + V L + +FA A IS E + + PI + T+L+++ +IQ +++L + + + + + ++D++K LI+ +++ APGQ+ECDEA+ +L + +++ + + + + R S+E+ N + +A+ ++ + I ++ A + E QL S+ Q E ++ + I AA++T Q L+ T+ E++ Q+L K++GGNPK + H+Q ++E Q + E+ EDL L++ + G V +V++IT++ ++ E + + F + Q+ M+ I + + T ++N + L L LT Y L + + A T NE G ++ VQ +G +LV ++ PS A + L +++ +++ V+ L + N GTQAC A + I +D+DT+I+F + + ++ E F R ++ + LV + K++V L ++A T LA VK+G L S + + L+ + ++V +L + + +G DP LK K + +TSLLK +K+++D K +A++ I I +E + SP ++S PE+ R+ + K + + RQE++ + + ++ ACK + V+ D +++ L + + Y ELL++ + L PT E + + + V S + ELI+
Sbjct: 4 LSLKISIGNVVKTMQFEPSTMVYDACRMIRERVPEAQMGQPNDFGLFLSDEDPKKGIWLEAGKALDYYMLRNGDTMEYKKKQRPLKIRMLDGTVKTVMVDDSKTVTDMLTTICARIGITNYDEYSLVREIME-EKKEEVTGTLKKDKTLLRDEKKMEKLKQKLHTDDELNWLDHGRTLREQGIDDNETLLLRRKFFYSDQNVDSRDPVQLNLLYVQARDDILNGSHPVSFDKACEFAGYQCQIQFGPHNEQKHKPGFLELKDFLPKEYIK--QKGERKIFMAHKNCGNMSEIEAKVRYVKLARSLKTYGVSFFLVKEKMKGKNKLVPRLLGITKECVMRVDEKTKEVIQEWSLTNIKRWAASPKSFTLDFGDYQ-DGYYSVQTTEGEQIAQLIAGYIDIILKKKKSKDHFGLEGDEESTMLEDSVSPKKSTVLQQQFNRVGKAELGSVALPAIMRTGAGGPENFQVGTMPQAQMQITSGQMHRGHMPPLTSAQQA-------------LTGTINSSMQAVNAAQATL-----DDFETL-------------PPLGQDAASKAWRKNKMDESKHEIHSQADAITAGTASVVNLTAGDPADTDYTAVGCAVTTISSNLTEMSKGVKLLAALME-------------DEGGNGRQLLQAAKNLASAVSDLLKTAQPASAEPR----QNLLQAAGLVGQTSGELLQQIGE-------------------SDTDPRFQDMLMQLAKAVASAAAALVLKAKNVAQKTEDSALQTQVIAAATQCALSTSQLVACTKVVAPTISSPVCQEQLIEAGKLVAKSAEGCVEASKAATNDDQLLKQVGVAATAVTQALNDLLQHIKQHATGGQPIGRYDQATDTILNVTENIFSSMGDAGEMVRQARILAQATSDLVNAI--KADAEGETDLENSRKLLSAAKILADATAKMVEAAKGAAAHPDSEEQQQRLREAAEGLRMAT-NAAAQNAIKKKLVHKLEHAAKQAAASATQTIAAAQHAAASNKNPAAQQQLVQSCKVVADQIPMLVQGVRGSQSQPDSPSAQLALIAASQNFLQPGGKMVAAAKATVPTITDQASAMQLSQCAKNLAAALAELRTAAQKAQEACGPLEIDSALGLVQSLERDLKEAKAAARDGKLKPLPGETMEKCAQDLGNSTKAVTSAIAHL---------LGEVAQGNENY--------TGIAAREVAQALRSLSQAARGVAAN------SSDPQAQN----AMLECASDVMD---KANNLIEEARKAVAKPGDPDSQQRLVQVAKAVSQALNRCVNCLPGQRDVDAAIRMVGEASKRLLSDSFP---PSNKTFQEAQSQLNRAAAGLNQSANELVQASRGTPQDLAKSSGKFGQD----------FNEFLQAGVEMASLSPTKEDQAQVVSNLKSISMSSSKLLLAAKALSADPTSPNLKSQLAAAARAVTDSINQLIT-MCTQQAPGQKECDNALRELETVKELLENPTQTVNDMSYFSCLDSVMENS-KVLGESMAGISQNAKNSKLPEFGESISAASKALCGLTEAAAQAAYLVGVSDPNSQAGQQGLVDPTQFARANQAIQMACQNLVDPACTQSQ----VLSAATIVAKHTSALCNTCRLASSRTANPVAKRQFVQPAKEVANSTANLVKTIKALDGAFNEENRERCRAATAPLIEAVDNLTAFASNPEFATVPAQISPEGRRAMEPIVTSAKTMLESSAGLIQTARSLAVNPKDPPQWSVLAGHSRTVSDSIKKLITNMRDKAPGQRECDEAIDVLNRCMREVDQASLAAISQ--QLAPREGISQEALHNQMITAVQEINNLIEPVASAARAEASQLGHKVSQMAQYFEPLILAAIGAASKTPNHQQQMNLLDQTKTLAESALQMLYTAKEAGGNPK-QAAHTQEALEEAVQMMKEAVEDLTTTLNEAASAAGVVGGMVDSITQAINQLDEGPMGEPEGTFVDYQTTMVKTAKAIAVTVQEMVTKSTTNPDE------LGILANQLTNDYGQLAQQAKPAALTAENEEIGSHIKRRVQELGHGCAALVTKAGALQCSPSDAYTKKELIESARKVSEKVSHVLAALQAGNRGTQACITAASAVSGIIADLDTTIMFATAGTLNREN------SETFADHREGILKTAKALVEDTKVLVQNATASQEKLAQAAQSSVSTITRLAEVVKLGAASLGSEDPETQVVLINAVKDVAKALGDLIGATKAAAGKAGDDPAVYQLKNSAKVMVTNVTSLLKTVKAVEDEATKGTRALEATI--------------EHIRQELAVFSSPVPPAQVST-----------PEDFIRMTKGITMATAKAVAAGNS-----CRQEDVIATANLSRRAIADMLRACKEAAYHPEVSADVRQRALRFGKECADGYLELLEHVLVILQKPTHELKQQLAGYSKRVASSVTELIQ 2284
BLAST of Talin-1 vs. UniProt/SwissProt
Match: sp|Q9Y4G6|TLN2_HUMAN (Talin-2 OS=Homo sapiens OX=9606 GN=TLN2 PE=1 SV=4) HSP 1 Score: 940.258 bits (2429), Expect = 0.000e+0 Identity = 717/2424 (29.58%), Postives = 1234/2424 (50.91%), Query Frame = 1
Query: 49 FELRIHIVDADVTKIVPLDPEATIFQLCETIRKNIREAQTKSPKSYGLYLPHDDLKKGLWLDNSKTLQHYILKRGDTIEYRNRSRWLHIRTMDGTNKTLKVDDSWTVSELMLTVCTKLGIYNYDEYSLISDKMDFSPGIDKTLSMKRGISINXXXXXXXXXXXXYHTEDGLNWLNPSQSLRQQGIEESEVLLLKRKYFFSDMNVDSRDPIQLSLLYEQLKDAVINGTHPVTLPEAIELAGLQCQVQLGNYSADKFKPGFLDLRECLPKEYQKNPKTVEKKIFNQHSKSKDLSEVEAKEKYCLLCRSFKTYGITFFLVKEKVIGKNKLIPRLLGVNKESVVQVDEKTKEIINTWPLTSIRKWAASFNGFTMDFGEYSPDEYYTAQTDKGERISQLIAGYIDIILKRKKAKDHLGVDADEESIMYEENIAPSKAIIVEHVPKQKRSSVSEEDVVIRKKAHMANSSVRMNSQASDSVCSQDCTDFYQEDINMSRQTSSLGRTQSPSSSLTTNSMHY-RMSDDDIRQKLYIISLQDNLDTIQKYKDQLMIENKGPEIGKDEASQQWIYVNIDNSRQRMADEIGAMNAAVAQVLRSAQGLATIXXXXXXXXXXXXIAKMQNSFSLITVHLPSLMEEIRTAAYYQDQLTDEDVSGEELIAAAKRLADAFTNLIKAAYPVEDQKRSLNRKEIFDAANAVGEASSDLLQQITEQENCQIELKSERPYSIIMITEEDQLYQEELLRLAKSVANETTNLIKQVKVIAVEAENPSDQKKVVMAATETGLAISQLISTTKIVAPTIEQSVCQEQLIFSIEDVSKAIQVVVESSNKATQSEELQDLTVQAANQVQEALDTLMKHLRXXXXXXXXXXXXXXAYENI----QEXXXXXXXXXXXXXXXRRLAQATTAMISEIQLKAVNEQYKTPEERDKLINAAKQLAEATTVLIDSAKNCTMDKDEMNLRYTLREATERFIVVTYTTECATYIQEQVIDHLLVAARKAATTGTHLINTSLSAA--KKSRASNFKVCNDGRELSNQISNLIVAIKEARRDPKDHLAQLELIAACRDYIDPSEQLSQSNKYMWPTVSDPSLQTALNQSINQSVIATEELKKCVHQADLMCQHLDLSAALEQLKRLEQNLKSIKNSIERENLIPLPDEKSDESAALLIKSVRRSGSAANQFKNDLESRCVVYEQTNGEDSYQNLENLDVAGQKARELSMALDRLVHAARGVAASIEFENQESENNDKNLEKLAQLQIVNNCLEAVKAARDLVIEAKS---SPPDNDQMDRAQQASVRXXXXXXXXXXXXPGQRDLDMLSKHIESKKHQFAENRLPIQQNNNINLSNCRSELTDTTFDFNQAVNELVSAPSFNLVNKGCKKMRMSYDRIVEICNVLVHDPFDESDSALHHLSSNRDHIANGVMI------MSEDCQTLLDKVKKIQCEPDNIIVRKQLQEATKMLLDSINRLLTNISTNLRPGQKECDKTIYRLESMRPILDNPVHPISHKDYFECLDFIIDKTVQPLADSLKNIPAAVKDENNQKFIDSIYHCADSVCMLLEETAQTAYLVGVGDVRSKIGNKGLADHTSFLQIQKEISENCQTICNPDTTARQDSSLMISTAGQIAENSRKLCEASK--TIMISFPNDKIKLSDKTKITLLAVSELMTGVQNLNQNFNEDNRKEVESLSGKVQDNVAELVQLLLSYKFAGDAAIISEEAKESQGPIKAAGITVLDTAIEVIQCSKALISSEANEELFIAYSSSCKDLNDALKHLISTIKESAPGQKECDEXXXXXXXXXXQAYDSKMKIMKHRSRTISRTFESEESYQNILQSALIQMPHCINELSRAGKKEPEQLARIFSRQTQLLESMVNSCICAANQTDLIQNSNIYLEHLITILEASEQLLKAVKKSGGNPKANSVHSQIDEMAQGVIESCEDLLAALDKISFKQGNVNTIVETITKSSAKVQESAIIPEKSRFGNSQSKMLDICYDMNNLTTDISSNANSESTQRLLAPLTQNLTQRYDDLCRACQGAVATLSNENNGKQLQECVQTVGKVSISLVK--STTEVRPSVASSISNLQAKTQELHKRIDDVIQLLISSNVGTQACTQAIKILKEINSDIDTSILFVKSADIQNDDREYYSVKELFKKSRNSVIDNSSELVRNIKLIVSKDVCDVNILQESADQIAITSQSLANDVKVGLEHLNSSTSQYNIELLVSFQEVIVSLISFLEVARNTSGLPYTDPLFQNLKEEGKCSINAITSLLKVLKSMDDVNLKDFQAIDNAIIXXXXXXXXXXXXXXGISREASPVESPTSTNRLSIGSDITVSPRFAPEEINRLIPSLANVCDKILEISSPEFKPIIRQENISVVSISCSKVNNELTSACKNLLRNGPVTDS-KKQTLNTVDQLVENYTELLKNFKLYLTNPTKE 7257
L+I + +V K + +P ++ C IR+ + EAQT YGL+L +D +KG+WL+ +TL +Y+L+ GD +EY+ + R IR +DG+ KT+ VDDS TV EL++T+C+++GI NY+EYSLI + ++ + T ++K+ ++ +D+ K++KLK K HT+D LNWL+ S++ R+QG++E+E LLL+RK+F+SD NVDSRDP+QL+LLY Q +D ++NG+HPV+ +A E G Q Q+Q G + K KPGFLDL+E LPKEY K + EK+IF +H ++SE+EAK KY L RS +TYG++FFLVKEK+ GKNKL+PRLLG+ K+SV++VDEKTKE++ WPLT++++WAAS FT+DFGEY + YY+ QT +GE+ISQLIAGYIDIILK+K++KD G++ DEES M EE+++P K+ I++ + R+ +E V + SS +T ++G SP + MH M Q+ + ++ ++ +Q+ +D L + P +G+D AS+ W+ +D S+ + ++ A+ A A V+ G + + + + + I+ +L + + ++ A D DE SGE+L+ AA+ LA A ++L+KA P + R + + AA ++G+AS DLL+QI E E D+ +Q+ L+ LAK+VAN L+ + K +A AE+ Q +V+ AAT+ L+ SQL++ K+V+PTI VCQEQLI + + V ++++ V + AT EL AA+ V +AL L++H+R+ + + + + A + I + + S D ++V AR LAQAT+ +++ ++ A E E KL+ AAK LA++T ++++AK + + + + LREA E V T I++++++ L VAA++AA T I S +AA K+ A+ ++ + +++ I L+ ++ ++ +D AQL LI + ++++ P ++ S K PTVSD + L+Q + EL+ +A C +++ +AL ++ L+ L+ K + L PLP E ++ A L + + GS+ Q C G + Y G ARE + AL L AARGVAAS + A ++++ + ++ + L+ EAK +P D ++ R Q + +S +L+ C++ LPGQ+D+D+ K I + + LP + +SEL D NQ+ E+V A + S D FDE A ++ + + + +S LL K + +P + L A + + +SIN+L+T + T PGQKECD + LE+++ +LDNP P+S YF+C++ +++ + + L +S+ I K + F + + + ++C L E AQ AYLVG+ D S+ G++GL D F + + I CQ + +P ++ Q ++S A +A+++ LC A + + + P K K + + L+ ++ L+ +F+EDNR + + + + V L + +F A IS E ++Q PI + T+L+++ +I+ +++L + + + + ++D++K LI++I++ APGQ+ECD ++ + + I+ + + + T R S E+ Q L S + ++ H I+ ++ A + E QL ++ E ++ + + A++ Q L+ T+ E++ Q+L A K+ GGNPKA H I E AQ + E+ +D++ L++ + + G V +V+ I ++ +K+ E K F + Q+ ++ Y T S + L L +T Y L Q A AT E G Q++ VQ +G I LV+ +V P+ + + L + + +++ V+ L + N GTQAC A + I +D+DT+I+F + + ++ E F R +++ + LV + KL+VS + L ++A A T LA VK+G L S + + L+ + ++V +L + + + P DP LK K + +TSLLK +K+++D + +A++ I I +E + +S + S +PEE R+ + K + + RQE++ + K +++ +ACK + V+D + + L + Y +LL++ + L PT E
Sbjct: 4 LSLKICVRHCNVVKTMQFEPSTAVYDACRVIRERVPEAQTGQASDYGLFLSDEDPRKGIWLEAGRTLDYYMLRNGDILEYKKKQRPQKIRMLDGSVKTVMVDDSKTVGELLVTICSRIGITNYEEYSLIQETIE-EKKEEGTGTLKKDRTLLRDERKMEKLKAKLHTDDDLNWLDHSRTFREQGVDENETLLLRRKFFYSDQNVDSRDPVQLNLLYVQARDDILNGSHPVSFEKACEFGGFQAQIQFGPHVEHKHKPGFLDLKEFLPKEYIKQ-RGAEKRIFQEHKNCGEMSEIEAKVKYVKLARSLRTYGVSFFLVKEKMKGKNKLVPRLLGITKDSVMRVDEKTKEVLQEWPLTTVKRWAASPKSFTLDFGEYQ-ESYYSVQTTEGEQISQLIAGYIDIILKKKQSKDRFGLEGDEESTMLEESVSPKKSTILQQ--QFNRTGKAEHGSVALPAVMRSGSS--------------------------GPETFNVGSMPSPQQQVMVGQMHRGHMPPLTSAQQALMGTINTSMHAVQQAQDDLSELDSLPPLGQDMASRVWVQNKVDESKHEIHSQVDAITAGTASVVNLTAG----------DPADTDYTAVGCAITTISSNLTEMSKGVKLLAALMD---DEVGSGEDLLRAARTLAGAVSDLLKAVQPTSGEPR----QTVLTAAGSIGQASGDLLRQIGENET-------------------DERFQDVLMSLAKAVANAAAMLVLKAKNVAQVAEDTVLQNRVIAAATQCALSTSQLVACAKVVSPTISSPVCQEQLIEAGKLVDRSVENCVRACQAATTDSELLKQVSAAASVVSQALHDLLQHVRQFASRGEPIGRYDQATDTIMCVTESIFSSMGDAGEMVRQARVLAQATSDLVNAMRSDA--EAEIDMENSKKLLAAAKLLADSTARMVEAAKGAAANPENEDQQQRLREAAEGLRVAT-NAAAQNAIKKKIVNRLEVAAKQAAAAATQTIAASQNAAVSNKNPAAQQQLVQSCKAVADHIPQLVQGVRGSQAQAEDLSAQLALIISSQNFLQPGSKMVSSAKAAVPTVSDQAAAMQLSQCAKNLATSLAELRTASQKAHEACGPMEIDSALNTVQTLKNELQDAKMAAVESQLKPLPGETLEKCAQDLGSTSKAVGSSMAQLLT-----CAA----QGNEHY--------TGVAARETAQALKTLAQAARGVAAS-------------TTDPAAAHAMLDSARDVMEGSAMLIQEAKQALIAPGDAERQQRLAQVAKAVSHSLNNCVNCLPGQKDVDVALKSIGESSKKLLVDSLP---PSTKPFQEAQSELNQAAADLNQSAGEVVHATRGQSGELAAASGKFS-------------DDFDEFLDAGIEMAGQAQTKEDQIQVIGNLKNISMASSKLLLAAKSLSVDPGAPNAKNLLAAAARAVTESINQLIT-LCTQQAPGQKECDNALRELETVKGMLDNPNEPVSDLSYFDCIESVMENS-KVLGESMAGISQNAKTGDLPAFGECVGIASKALCGLTEAAAQAAYLVGISDPNSQAGHQGLVDPIQFARANQAIQMACQNLVDPGSSPSQ----VLSAATIVAKHTSALCNACRIASSKTANPVAKRHFVQSAKEVANSTANLVKTIKALDGDFSEDNRNKCRIATAPLIEAVENLTAFASNPEFVSIPAQISSEGSQAQEPILVSAKTMLESSSYLIRTARSLAINPKDPPTWSVLAGHSHTVSDSIKSLITSIRDKAPGQRECDYSIDGINRCIRDIEQASLAAVSQSLAT--RDDISVEALQEQLTSVVQEIGHLIDPIATAARGEAAQLGHKVTQLASYFEPLILAAVGVASKILDHQQQMTVLDQTKTLAESALQMLYAAKEGGGNPKAQHTHDAITEAAQLMKEAVDDIMVTLNEAASEVGLVGGMVDAIAEAMSKLDEGTPPEPKGTFVDYQTTVVK--YSKAIAVTAQEMMTKSVTNPEELGGLASQMTSDYGHLAFQGQMAAATAEPEEIGFQIRTRVQDLGHGCIFLVQKAGALQVCPTDSYTKRELIECARAVTEKVSLVLSALQAGNKGTQACITAATAVSGIIADLDTTIMFATAGTLNAEN------SETFADHRENILKTAKALVEDTKLLVSGAASTPDKLAQAAQSSAATITQLAEVVKLGAASLGSDDPETQVVLINAIKDVAKALSDLISATKGAASKPVDDPSMYQLKGAAKVMVTNVTSLLKTVKAVEDEATRGTRALEATI--------------ECIKQELTVFQSKDVPEKTS-----------SPEESIRMTKGITMATAKAVAAGNS-----CRQEDVIATANLSRKAVSDMLTACKQASFHPDVSDEVRTRALRFGTECTLGYLDLLEHVLVILQKPTPE 2265
BLAST of Talin-1 vs. UniProt/SwissProt
Match: sp|Q71LX4|TLN2_MOUSE (Talin-2 OS=Mus musculus OX=10090 GN=Tln2 PE=1 SV=3) HSP 1 Score: 831.247 bits (2146), Expect = 0.000e+0 Identity = 599/1917 (31.25%), Postives = 1022/1917 (53.31%), Query Frame = 1
Query: 49 FELRIHIVDADVTKIVPLDPEATIFQLCETIRKNIREAQTKSPKSYGLYLPHDDLKKGLWLDNSKTLQHYILKRGDTIEYRNRSRWLHIRTMDGTNKTLKVDDSWTVSELMLTVCTKLGIYNYDEYSLISDKMDFSPGIDKTLSMKRGISINXXXXXXXXXXXXYHTEDGLNWLNPSQSLRQQGIEESEVLLLKRKYFFSDMNVDSRDPIQLSLLYEQLKDAVINGTHPVTLPEAIELAGLQCQVQLGNYSADKFKPGFLDLRECLPKEYQKNPKTVEKKIFNQHSKSKDLSEVEAKEKYCLLCRSFKTYGITFFLVKEKVIGKNKLIPRLLGVNKESVVQVDEKTKEIINTWPLTSIRKWAASFNGFTMDFGEYSPDEYYTAQTDKGERISQLIAGYIDIILKRKKAKDHLGVDADEESIMYEENIAPSKAIIVEHVPKQKRSSVSEEDVVIRKKAHMANSSVRMNSQASDSVCSQDCTDFYQEDINMSRQTSSLGRTQSPSSSLTTNSMHY-RMSDDDIRQKLYIISLQDNLDTIQKYKDQLMIENKGPEIGKDEASQQWIYVNIDNSRQRMADEIGAMNAAVAQVLRSAQGLATIXXXXXXXXXXXXIAKMQNSFSLITVHLPSLMEEIRTAAYYQDQLTDEDV-SGEELIAAAKRLADAFTNLIKAAYPVEDQKRSLNRKEIFDAANAVGEASSDLLQQITEQENCQIELKSERPYSIIMITEEDQLYQEELLRLAKSVANETTNLIKQVKVIAVEAENPSDQKKVVMAATETGLAISQLISTTKIVAPTIEQSVCQEQLIFSIEDVSKAIQVVVESSNKATQSEELQDLTVQAANQVQEALDTLMKHLRXXXXXXXXXXXXXXAYENI----QEXXXXXXXXXXXXXXXRRLAQATTAMISEIQLKAVNEQYKTPEERDKLINAAKQLAEATTVLIDSAKNCTMDKDEMNLRYTLREATERFIVVTYTTECATYIQEQVIDHLLVAARKAATTGTHLINTSLSAA--KKSRASNFKVCNDGRELSNQISNLIVAIKEARRDPKDHLAQLELIAACRDYIDPSEQLSQSNKYMWPTVSDPSLQTALNQSINQSVIATEELKKCVHQADLMCQHLDLSAALEQLKRLEQNLKSIKNSIERENLIPLPDEKSDESAALLIKSVRRSGSAANQFKNDLESRCVVYEQTNGEDSYQNLENLDVAGQKARELSMALDRLVHAARGVAASIEFENQESENNDKNLEKLAQLQIVNNCLEAVKAARDLVIEAKS---SPPDNDQMDRAQQASVRXXXXXXXXXXXXPGQRDLDMLSKHIESKKHQFAENRLPIQQNNNINLSNCRSELTDTTFDFNQAVNELVSAPSFNLVNKGCKKMRMSYDRIVEICNVLVHDPFDESDSALHHLSS------NRDHIANGVMIMSEDCQTLLDKVKKIQCEPDNIIVRKQLQEATKMLLDSINRLLTNISTNLRPGQKECDKTIYRLESMRPILDNPVHPISHKDYFECLDFIIDKTVQPLADSLKNIPAAVKDENNQKFIDSIYHCADSVCMLLEETAQTAYLVGVGDVRSKIGNKGLADHTSFLQIQKEISENCQTICNPDTTARQDSSLMISTAGQIAENSRKLCEASK--TIMISFPNDKIKLSDKTKITLLAVSELMTGVQNLNQNFNEDNRKEVESLSGKVQDNVAELVQLLLSYKFAGDAAIISEEAKESQGPIKAAGITVLDTAIEVIQCSKALISSEANEELFIAYSSSCKDLNDALKHLISTIKESAPGQKECDEXXXXXXXXXXQAYDSKMKIMKHRSRTISRTFESEESYQNILQSALIQMPHCINELSRAGKKEPEQLARIFSRQTQLLESMVNSCICAANQTDLIQNSNIYLEHLITILEASEQLLKAVKKSGGNPKANSVHS 5742
L+I + +V K + +P ++ C IR+ + EAQT YGL+L +D +KG+WL+ +TL +Y+L+ GD +EY+ + R IR +DG+ KT+ VDDS TV EL++T+C+++GI NY+EYSLI + ++ + T ++K+ ++ +D+ K++KLK K HT+D LNWL+ S++ R+QG++E+E LLL+RK+F+SD NVDSRDP+QL+LLY Q +D ++NG+HPV+ +A E G Q Q+Q G + K KPGFLDL+E LPKEY K + EK+IF +H ++SE+EAK KY L RS +TYG++FFLVKEK+ GKNKL+PRLLG+ K+SV++VDEKTKE++ WPLT++++WAAS FT+DFGEY + YY+ QT +GE+ISQLIAGYIDIILK+K++KD G++ DEES M EE+++P +KRS++ ++ KA + ++ ++ S +T ++G SP + MH M Q+ + ++ ++ +Q+ +D L + P +G+D AS+ W+ +D S+ + ++ A+ A A V+ G + + + + + I+ +L + + ++ A L D+DV SGE+L+ AA+ LA A ++L+KA P + R+ + AA ++G+AS DLL+QI E E D+ +Q+ L+ LAK+VAN L+ + K +A AE+ Q +V+ AAT+ L+ SQL++ K+V+PTI VCQEQLI + + V ++++ V + AT EL AA+ V +AL L++H+R+ + + + + A + I + + S D ++V AR LAQAT+ +++ ++ A E E KL+ AAK LA++T ++++AK + + + + LREA E V T I++++++ L VAA++AA T I S +AA K+ ++ ++ + +++ I L+ ++ ++ +D AQL LI + ++++ P ++ S K PTVSD + L+Q + EL+ +A C +++ +AL ++ L+ L+ K + L PLP E ++ A L + + GS+ Q C G + Y G ARE + AL L AARGVAAS ND A ++++ + ++ + L+ EAK +P D + R Q + +S +L+ C++ LPGQ+D+D+ K I + + LP + +SEL D NQ+ E+V A + S D FDE A ++ ++ + + +S LL K + +P + L A + + +SIN+L+ + T PGQKECD + LE+++ +L+NP P+S YF+C++ +++ + + L +S+ I K + F + + + ++C L E AQ AYLVG+ D S+ G++GL D F + + I CQ + +P ++ Q ++S A +A+++ LC A + + + P K K + + L+ ++ L+ +F+EDNR + + + + V L + +FA A IS E ++Q PI + T+L+++ +I+ +++L + + + + ++D++K LI++I++ APGQ+ECD ++ + + I+ + + + T R S E+ Q L S + ++ H I+ ++ A + E QL ++ E ++ + + A++ Q L+ T+ E++ Q+L A K+ GGNPKA VH+
Sbjct: 4 LSLKICVRHCNVVKTMQFEPSTAVYDACRVIRERVPEAQTGQASDYGLFLSDEDPRKGIWLEAGRTLDYYMLRNGDILEYKKKQRPQKIRMLDGSVKTVMVDDSKTVGELLVTICSRIGITNYEEYSLIQETIE-EKKEEGTGTLKKDRTLLRDERKMEKLKAKLHTDDDLNWLDHSRTFREQGVDENETLLLRRKFFYSDQNVDSRDPVQLNLLYVQARDDILNGSHPVSFEKACEFGGFQAQIQFGPHVEHKHKPGFLDLKEFLPKEYIKQ-RGAEKRIFQEHKNCGEMSEIEAKVKYVKLARSLRTYGVSFFLVKEKMKGKNKLVPRLLGITKDSVMRVDEKTKEVLQEWPLTTVKRWAASPKSFTLDFGEYQ-ESYYSVQTTEGEQISQLIAGYIDIILKKKQSKDRFGLEGDEESTMLEESVSP-----------KKRSTILQQQFNRTGKAEHGSVALPAVMRSGSS----------------GPETFNVGSMPSPQQQVMVGQMHRGHMPPLTSAQQALMGTINTSMHAVQQAQDDLSELDSLPPLGQDMASRVWVQNKVDESKHEIHSQVDAITAGTASVVNLTAG----------DPADTDYTAVGCAITTISSNLTEMSKGVKLLAA----LMDDDVGSGEDLLRAARTLAGAVSDLLKAVQPTSGEP----RQTVLTAAGSIGQASGDLLRQIGENET-------------------DERFQDVLMSLAKAVANAAAMLVLKAKNVAQVAEDTVLQNRVIAAATQCALSTSQLVACAKVVSPTISSPVCQEQLIEAGKLVDRSVENCVRACQAATSDSELLKQVSAAASVVSQALHDLLQHVRQFASRGEPIGRYDQATDTIMCVTESIFSSMGDAGEMVRQARVLAQATSDLVNAMRSDA--EAEIDMENSKKLLAAAKLLADSTARMVEAAKGAAANPENEDQQQRLREAAEGLRVAT-NAAAQNAIKKKIVNRLEVAAKQAAAAATQTIAASQNAAISNKNPSAQQQLVQSCKAVADHIPQLVQGVRGSQAQAEDLSAQLALIISSQNFLQPGSKMVSSAKAAVPTVSDQAAAMQLSQCAKNLATSLAELRTASQKAHEACGPMEIDSALNTVQTLKNELQDAKMAAAESQLKPLPGETLEKCAQDLGSTSKGVGSSMAQLLT-----CAA----QGNEHY--------TGVAARETAQALKTLAQAARGVAAS---------TNDPE----AAHAMLDSARDVMEGSAMLIQEAKQALIAPGDTESQQRLAQVAKAVSHSLNNCVNCLPGQKDVDVALKSIGEASKKLLVDSLP---PSTKPFQEAQSELNQAAADLNQSAGEVVHATRGQSGELAAASGKFS-------------DDFDEFLDAGIEMAGQAQTKEDQMQVIGNLKNISMASSKLLLAAKSLSVDPGAPNAKNLLAAAARAVTESINQLIM-LCTQQAPGQKECDNALRELETVKGMLENPNEPVSDLSYFDCIESVMENS-KVLGESMAGISQNAKTGDLPAFGECVGIASKALCGLTEAAAQAAYLVGISDPNSQAGHQGLVDPIQFARANQAIQMACQNLVDPGSSPSQ----VLSAATIVAKHTSALCNACRIASSKTANPVAKRHFVQSAKEVANSTANLVKTIKALDGDFSEDNRNKCRIATTPLIEAVENLTAFASNPEFASIPAQISSEGSQAQEPILVSAKTMLESSSYLIRTARSLAINPKDPPTWSVLAGHSHTVSDSIKSLITSIRDKAPGQRECDYSIDGINRCIRDIEQASLAAVSQSLAT--RDDISVEALQEQLTSVVQEIGHLIDPIATAARGEAAQLGHKVTQLASYFEPLILAAVGVASKMLDHQQQMTVLDQTKTLAESALQMLYAAKEGGGNPKA--VHT 1794 HSP 2 Score: 85.8853 bits (211), Expect = 1.057e-14 Identity = 67/254 (26.38%), Postives = 124/254 (48.82%), Query Frame = 1
Query: 6073 AVATLSNENNGKQLQECVQTVGKVSISLVK--STTEVRPSVASSISNLQAKTQELHKRIDDVIQLLISSNVGTQACTQAIKILKEINSDIDTSILFVKSADIQNDDREYYSVKELFKKSRNSVIDNSSELVRNIKLIVSKDVCDVNILQESADQIAITSQSLANDVKVGLEHLNSSTSQYNIELLVSFQEVIVSLISFLEVARNTSGLPYTDPLFQNLKEEGKCSINAITSLLKVLKSMDDVNLKDFQAIDNAI 6828
A+A + E G Q++ VQ +G I LV+ +V P+ + + L + + +++ V+ L + N GTQAC A + I +D+DT+I+F + + ++ E F R +++ + LV + KL+VS + L ++A A T LA VK+G L S+ + + L+ + ++V +L + + + P DP LK K + +TSLLK +K+++D + +A++ I
Sbjct: 1815 AIAVTAQEMIGFQIRTRVQDLGHGCIFLVQKAGALQVCPTDSYTKRELIECARSVTEKVSLVLSALQAGNKGTQACITAATAVSGIIADLDTTIMFATAGTLNAEN------GETFADHRENILKTAKALVEDTKLLVSGAASTPDKLAQAAQSSAATITQLAEVVKLGAASLGSNDPETQVVLINAIKDVAKALSDLIGATKGAASKPADDPSMYQLKGAAKVMVTNVTSLLKTVKAVEDEATRGTRALEATI 2062
BLAST of Talin-1 vs. TrEMBL
Match: A0A504YNR7 (Talin OS=Fasciola gigantica OX=46835 GN=FGIG_00042 PE=4 SV=1) HSP 1 Score: 1498.03 bits (3877), Expect = 0.000e+0 Identity = 989/2894 (34.17%), Postives = 1590/2894 (54.94%), Query Frame = 1
Query: 28 MLNSNGNFELRIHIVDADVTKIVPLDPEATIFQLCETIRKNIREA-QTKSPKSYGLYLPHDDLKKGLWLDNSKTLQHYILKRGDTIEYRNRSRWLHIRTMDGTNKTLKVDDSWTVSELMLTVCTKLGIYNYDEYSLIS--DKMDFSPGIDKTLSMKRG----ISINXXXXXXXXXXXXYHTEDGLNWLNPSQSLRQQGIEESEVLLLKRKYFFSDMNVDSRDPIQLSLLYEQLKDAVINGTHPVTLPEAIELAGLQCQVQLGNYSADKFKPGFLDLRECLPKEYQKNPKTVEKKIFNQHSKSKDLSEVEAKEKYCLLCRSFKTYGITFFLVKEKVIGKNKLIPRLLGVNKESVVQVDEKTKEIINTWPLTSIRKWAASFNGFTMDFGEYSPDEYYTAQTDKGERISQLIAGYIDIILKRKKAKDHLGVDADEESIMYEENIAPSKAIIVEH--VPKQKRSSVSE-------EDVVIRKKAHMANSSVRMNSQASDSVCSQ-----DCTDFYQEDINMSRQTSSLGRTQSPSSSLTTNSMHYRMSDDDIRQKLYIISLQDNLDTIQKYKDQLMIENKGPE----IGKDEASQQWIYVNIDNSRQRMADEIGAMNAAVAQVLRSAQ------GLATIXXXXXXXX-XXXXIAKMQNSFSLITVHLPSLMEEIRTAAYYQ--------DQLTDEDV------SGEELIAAAKRLADAFTNLIKAAYPVEDQK------------------------------RSLNRKEIFDAANAVGEASSDLLQQITEQENCQIELKSERPYSIIMITEEDQLYQEELLRLAKSVANETTNLIKQVKVIAVEAE-NPSDQKKVVMAATETGLAISQLISTTKIVAPTIEQSVCQEQLIFSIEDVSKAIQVVVESSNK-----ATQSEELQDLTVQ--------AANQVQEALDTLMKHLRXXXXXXXXXXXX---XXAYENIQEXXXXXXXXXXXXXXXRRLAQATTAMISEIQLKAVNEQYKTPEERDKLINAAKQLAEATTVLIDSAKNCTMDKDEMNLRYTLREATERFIVVTYTTECATYIQEQVIDHLLVAARKAATTGTHLINTSLSAAKKSRASNFKVCNDGRELSNQISNLIVAIKEARRDPKDHLAQLELIAACRDYIDPSEQLSQSNKYMWPTVSDPSLQTALNQSINQSVIATEELKKCVHQADLMCQHLDLSAALEQLKRLEQNLKSIKNSIERENLIPLPDEKSDESAALLIKSVRRSGSAANQFKNDLESRCVVYEQTNGEDSYQN---LENLDVAGQKARELSMALDRLVHAARGVAASIEFENQESENNDKNLEKL--AQLQIVNNCLEAVKAARDLVIEAKSSPPDNDQMDRAQQASVRXXXXXXXXXXXXPGQRDLDMLSKHIE-SKKHQFAENRLPIQQNNNINLS-----------------NCRSELTDTTFDFNQAVNELVSAPSFNLVNKGCKKMRMSYDRIVE------ICNVLVHDPFDESDSALHHLSSNRDHIANGVMIMSEDCQTLLDKVKKIQCEPDNIIVRKQLQEATKMLLDSINRLLTNISTNLRPGQKECDKTIYRLESMRPILDNPVHPISHKDYFECLDFIIDKTVQPLADSLKNIPAAVKDENNQKFIDSIYHCADSVCMLLEETAQTAYLVGVGDVRSKIGNKGLADHTSFLQIQKEISENCQTICNPDTTARQDSSLMISTAGQIAENSRKLCEASKTIMISFP--NDKIKLSDKTKITLLAVSELMTGVQNL-------NQNFNEDNRKEVESLSGKVQDNVAELVQLLLSY-KFAGDAAIISEEAKESQGPIKAAGITVLDTAIEVIQCSKALIS---SEANEELFIAYSSSCKDLNDALKHLISTIKESAPGQKECDEXXXXXXXXXXQAYDSKMKIMKHRSRTISRTFESEESYQNILQSALIQMPHCINELSRAGKKEPEQLARIFSRQTQLLESMVNSCICAANQTDLIQNSNIYLEHLITILEASEQLLKAVKKSGGNPKANSVHSQIDEMAQGVIESCEDLLAALDKISFKQGNVNTIVETITKSSAKVQESAIIPEKSRFGNSQSKMLDICYDMNNLTTDISSNANSESTQRLLAPLTQNLTQRYDDLCRACQGAVATLSNENNGKQLQECVQTVGKVSISLVKSTTEVR-------------PSVASSISNLQAKTQELHKRIDDVIQLLISSNVGTQACTQAIKILKEINSDIDTSILFVKSADIQ---NDD-------REYYSVKEL-------------------FKKSRNSVIDNSSELVRNIKLIVSKDVCDVNILQESADQIAITSQSLANDVKVGLEHLNSSTSQYNIELLVSFQEVIVSLISFLEVARNTSGLPYTDPLFQNLKEEGKCSINAITSLLKVLKSMDDVNLKDFQAI--------DNAIIXXXXXXXXXXXXXXGISREA--SPVES----PTSTNRLSIGSDITVSPRF-APEEINRLIPS-LANVCDKILEISSPEFKPIIRQENISVVSISCSKVNNELTSACKNLLR-NGPVTDSKKQTLNTVDQLVENYTELLKNFKLYLTNPTKET---RIPVETVVSKLNELIKLLRDQVNLLREGPRLVMYFRPSSPEWRDVSEKYIGRHVAYHHCFVKSYN----HDSHTSLHHHQAPF-IQLPINTRDPSEVDLDT---AKNQIKFVTTKLIDIKLNPDLIGKDKCSVAEVDQMLSYIKDIGWSTEELLSSSQEI--CKSNSDTDNEIWNIDFKKEIFKSAIGVSNAMKDLCEAA---SKPLSTGCSPTWG--------------------DRMSTSTRKVANSTGQLLLNLKP-TVIQNKSQIEKIHTHGNQIKKNTDLL 8016
M+ N + LR+H + VTK + D + T+ Q CE IR +RE+ QT K +GL+LPH+D KKGLWLDN++TL+HYIL+ GDT+EYR R RWL+IRTMDGT K L VDDS +V+ELML +CTK+GIYN++EYSL+ D+ D D++ +++R ++I +DQEK++KLK+K HT+D ++WLNPSQSLRQQGI+E EVLLLKR+YFFSDMNVD+RDP+QL+LLY QLKDA++ GTHPV+L EAI LA +QCQVQ G+Y +KFKP FLDL++ LPKEY K +++EKKIF QH++ LSEV+AK +YC CRS KTYGITFFLVKE++ GKNKLIPRLLGV K+ V+++DE+TKE++ TWPLTSI +WAAS + FTMDFGEYSPD+ YTAQT +GE+ISQLIAGY+DII K++KAKDH G DEES MYEEN+ +A IV+H +P + E E ++ R + S++M++ + SQ D + +++ R SP + + + + + Q+ ++++ ++++T+Q K+QL I G +G DE S++W+ ++ S+ ++ DE+GAMNAAVAQ LRSA G+ + + + MQ SF ++T+H P+ +++++ A + DQ + V S + L++AA+ +ADAFT+L+++A P+ S +RK I +AA+ VGEAS+DLL+ + + + E + ++TEE++LYQ+ LL LAK+VAN T L+ + K +A + +P Q++V+ AAT+TGL SQL++ TK++APTI Q CQ+QL + +VS A+ VV++S A Q ++Q +VQ AA +V++ALD L HL K K D LAYEN+Q+ + +LV++ARRLAQAT MI++I+ +A P+ + +L AAKQLA+ATT LI+ AK C+ + D++ L+ LREA E V+ Y+ A + ++I L AAR T T L+N S A K+SR + ++V +D + ++ I I++I+E+R +P D + Q+ELI AC ++ P E L +S++ + PTVSDP++Q AL+ S Q V A E L+ C+ + + +HL + AL +L RL +I+ S+++ L+PLPDEK ++ LL SV+ ++ + ++ +E ++Q+ + D+ G A L+ A+ LV A RGV A F++ +SE + + A+ + + ++V+ A +LV A + +D A A+V R L L H E S+ E R +N+ INLS +S+LT +FNQA +L+S+ S + ++ +YD++ + + V P N+D + NG++ +S+ L+ + ++ P+ +R + Q A + + +SI++LLT +T + P ++C+ + RL+++RP+L+NP P++ + Y++C+D + K++ PLADSL+N+ + +D+ Q+F ++ CA+S+C L+EETAQ AYL+G+ D RS+ G L + FL+ Q+EI E C IC+P T RQ +IS + ++A +++ LCEA ++ P + + +L++ T+ T+ +++ L+ N+ N + E NR+ + + V NV+ LV LL + +FAG AA +++EA+ESQ P+ +AG+ L+ A V++ ++ LI+ + +E F +SS+ KDL++++K L S +++ APGQ+EC L +A L++ +KM M++ + R +EE +Q L ++ + L RA + E EQL L + ++ I AA+++ L YLEH T+LEA++QL+ + +GGNP+A +H+ +D+ +GV++SCEDLL ALD I+ +QG+V+T+++T+ ++ A+ +E +P +RF + Q++ML I M L I A S++ L PL LTQ Y ++C+ C+GA ATL + + +L+ V+ VG S LV +TT R S I++L + + L ++ ++I LL TQAC Q+ + I +D+DT+ILF S + +DD EY+S EL F R S++ + LV + + +VS D L +A LAN VK G + +ELL + ++V +L S + A DP+ ++ + +++ IT+LL+ +K+++D + QA+ D A + G A +PV S P+ N ++ + ++ R+ AP+++ R + + K++ S+ + Q ++ + + V +L +A K LLR + +++ + T +L E + ELL K L + RIP T ++ +L L + + LREGPRLVMYFR SSPEWRDV+EK+IGRHVAYHH +V +Y+ +H S++ + ++LP +T + + T A+++I+ +L +PD KD S +L + + + L+ +++ I ++ + ++++ + VS A + +C+ + S+ L CS G +R+ RKVA ++ QLL+ K + + I+K+ G +K+ TD L
Sbjct: 10 MVGDNRSLALRVHFPKSGVTKTMVFDAQMTVGQACEHIRAQMRESDQTDGTKDHGLFLPHEDNKKGLWLDNARTLEHYILRNGDTVEYRYRYRWLYIRTMDGTRKKLCVDDSKSVAELMLMICTKMGIYNHEEYSLVREHDENDR----DRSSTLRRQGTGMVTIGRDQEKMEKLKRKLHTDDDMDWLNPSQSLRQQGIDEREVLLLKRRYFFSDMNVDARDPVQLNLLYVQLKDAILKGTHPVSLEEAIRLAAIQCQVQFGDYVPEKFKPNFLDLKDFLPKEYAKL-RSLEKKIFQQHAEMIGLSEVDAKFEYCQFCRSLKTYGITFFLVKERIKGKNKLIPRLLGVTKDKVIRLDERTKEVLKTWPLTSISRWAASLHAFTMDFGEYSPDDCYTAQTSEGEQISQLIAGYVDIITKKQKAKDHAGFQGDEESAMYEENVRAERATIVQHQRMPPTRGPRAKEGLLNGTAEPLISRDM----DDSIQMSAVHRINGWSQQHIIGDGMSTVVDGQSIATSGVQPPRQMSPDNFMIGGTHIFHYQEMTPAQRALLVTINEDVETLQAAKEQLQIGPAGERVLLGVGSDETSRRWLSESLGASQAKVTDEMGAMNAAVAQALRSANRAEAYDGIPPAQAGLGASSDPGDDLMMMQQSFRVVTIHFPAFVDDVKRVAVLRREAGAIRADQTGEPTVAEQTEESTQNLLSAARYVADAFTDLLESARPLASGHTREVMDGTDDTATGSHAVITTTTTTTGGPVSSSSRKAIIEAASRVGEASNDLLRHVMNESGDDV---LESTTHLQLLTEEERLYQDHLLSLAKAVANATAGLVVKAKNLATQPNLDPEAQQRVIAAATQTGLCTSQLVACTKVLAPTIHQPSCQQQLSEAAREVSWAVDGVVQASRAVGLTLADQPPQIQH-SVQMAVTDTETAATEVRDALDALNAHLLKASAKAYSGDALDNFQLAYENLQQ--NHAGGGQRLVASARRLAQATAQMIADIKAQA-ELSGDDPDRQSRLFAAAKQLADATTNLIEVAKVCSANPDDIMLQNELREAAENLNVIAYSA-AAELLHTRLIRSLQAAARATVTGATQLVNVSQVAGKRSRGNTYQVISDAKAVNGMIPRTIISIRESRANPDDPMTQMELIGACERFVQPCEALIRSSRSIAPTVSDPTVQAALDNSTAQLVSAVETLRACLGRLAPLSRHLQIDGALARLARLSVEAAAIETSLQQGTLVPLPDEKVEDCFHLLSMSVQDGSASTRELQSIIEGL-----------AHQDPDIVNRPDICGMPATSLASAMAGLVQATRGVVAHEGFDSLDSELSPSMGPAVESARRAVTQDTRQSVQLAYELVKAASDARIASDTHQTATLATVLSHSEQLSAQLLDALSRCLRGLPGHREISEATHLIERR----RNDLINLSQSAPTRKVRLVEPSEYERAQSDLTRAAVEFNQATGDLLSSYSPGTFRRTTRRFTGAYDQLTDKGVELSLTGVPCTPPGQP--------QVNQD-LVNGLVTVSDQSHALMTQASRVCARPEEQDLRSRFQAAARDVTESISQLLTICTTGVTPDHRDCEVALRRLDALRPLLENPNRPVNQQAYYDCVDSVA-KSLSPLADSLRNMSNSARDQQTQEFGSAVRQCANSMCQLVEETAQAAYLIGLADPRSEPGKPSLVNTQLFLRTQQEIQEVCDAICSPSVTNRQ----VISLSTEMARSAKVLCEACSSVSAQTPSVDARQQLNNLTRETMQSITALIQHQGNMVNTSGATNGEWAEANRQTTLASAQAVSSNVSRLVHLLTTGPQFAGHAARVTDEARESQVPVCSAGLASLNAAQSVLRAAQNLITNARTSQSEMAFKGFSSASKDLSESIKTLASAMRDHAPGQRECQHVLNNIAHLMQDLQQAKMASMENHLQ--PRRELNEEGFQKQLATSTRALLDAAPALGRAARSEAEQLGHAALLVDSYLPGLTSNAIAAASRSPLSSTQLTYLEHACTVLEATDQLVTVARDAGGNPRAAHLHNPLDDAVRGVMDSCEDLLVALDDIASRQGHVSTLIDTLNRALAQTEEIIQVPVDARFSDYQARMLRIARHMEQLNQAIQLRARQPSSEGELTPLAHTLTQEYQEMCQTCKGAAATLPDAHQADELRAAVRAVGLASADLVHATTGSRLRGSDVHGGQQMFLSRNRGIADLDKRAELLDFKLRELIALLDLRGPNTQACLQSASTVSGIIADLDTTILFASSGTLHPPIHDDVDALLSGDEYHSRYELTGPDALDRRGGPGSQSTESFGPIRESIVRTARALVDDTQNLVSGTGEDQARLASTAHTAVERVTQLANVVKRGAAVIGPGQPDTQVELLSACRDVATALRSVFQSASQLPARTVDDPVVNEVRTNAQLTVSGITALLQKVKAIEDDERRGLQALTLAAKYCRDQASQLAPTVTNAGGDSTTGTETAAILTPVSSRKSAPSVANMSAVSNTSSLIARYLAPDDLARAASGPVQSAVSKVILASNTQ-----SQGDVLATAAATRDVVTDLVAATKALLRFSEAAPETRSACVVTSKELSEEFAELLDALKATLLPSCRAADRERIPNST--RRIADLSHSLLNLLGTLREGPRLVMYFRASSPEWRDVAEKFIGRHVAYHHHYVPNYSIAGPGYTHRSVYIRPTCYPLRLPHDTTEANATADSTEAEAESRIQLAIQQLEQALTSPDESSKDSAS------LLRVAHSVALAAQNLIRTARSIGLVPASEPAERARHAPHRSASLWRTELTVSLATQHMCQLSLLCSEALRAECSAQGGVGKANADELFGTSMRLVPSRERLLAEVRKVAAASAQLLMWAKARKLTYGANDIQKLQAAGQSVKETTDRL 2842
BLAST of Talin-1 vs. TrEMBL
Match: A0A4E0S2C9 (Talin OS=Fasciola hepatica OX=6192 GN=D915_001787 PE=4 SV=1) HSP 1 Score: 1493.02 bits (3864), Expect = 0.000e+0 Identity = 993/2903 (34.21%), Postives = 1593/2903 (54.87%), Query Frame = 1
Query: 28 MLNSNGNFELRIHIVDADVTKIVPLDPEATIFQLCETIRKNIREA-QTKSPKSYGLYLPHDDLKKGLWLDNSKTLQHYILKRGDTIEYRNRSRWLHIRTMDGTNKTLKVDDSWTVSELMLTVCTKLGIYNYDEYSLIS--DKMDFSPGIDKTLSMKRG----ISINXXXXXXXXXXXXYHTEDGLNWLNPSQSLRQQGIEESEVLLLKRKYFFSDMNVDSRDPIQLSLLYEQLKDAVINGTHPVTLPEAIELAGLQCQVQLGNYSADKFKPGFLDLRECLPKEYQKNPKTVEKKIFNQHSKSKDLSEVEAKEKYCLLCRSFKTYGITFFLVKEKVIGKNKLIPRLLGVNKESVVQVDEKTKEIINTWPLTSIRKWAASFNGFTMDFGEYSPDEYYTAQTDKGERISQLIAGYIDIILKRKKAKDHLGVDADEESIMYEENIAPSKAIIVEH--VPKQKRSSVSEEDVVIRKKAHMANSSVRMNSQASDSVCSQDCTDFYQ----EDINMSRQTSSLG--------------------RTQSPSSSLTTNSMHYRMSDDDIRQKLYIISLQDNLDTIQKYKDQLMIENKGPE----IGKDEASQQWIYVNIDNSRQRMADEIGAMNAAVAQVLRSAQ------GLATIXXXXXXXX-XXXXIAKMQNSFSLITVHLPSLMEEIRTAAYYQ--------DQLTDEDV------SGEELIAAAKRLADAFTNLIKAAYPVEDQK------------------------------RSLNRKEIFDAANAVGEASSDLLQQITEQENCQIELKSERPYSIIMITEEDQLYQEELLRLAKSVANETTNLIKQVKVIAVEAE-NPSDQKKVVMAATETGLAISQLISTTKIVAPTIEQSVCQEQLIFSIEDVSKAIQVVVESSNKAT-----QSEELQDLTVQ--------AANQVQEALDTLMKHLRXXXXXXXXXXXX---XXAYENIQEXXXXXXXXXXXXXXXRRLAQATTAMISEIQLKAVNEQYKTPEERDKLINAAKQLAEATTVLIDSAKNCTMDKDEMNLRYTLREATERFIVVTYTTECATYIQEQVIDHLLVAARKAATTGTHLINTSLSAAKKSRASNFKVCNDGRELSNQISNLIVAIKEARRDPKDHLAQLELIAACRDYIDPSEQLSQSNKYMWPTVSDPSLQTALNQSINQSVIATEELKKCVHQADLMCQHLDLSAALEQLKRLEQNLKSIKNSIERENLIPLPDEKSDESAALLIKSVRRSGSAANQFKNDLESRCVVYEQTNGEDSYQN---LENLDVAGQKARELSMALDRLVHAARGVAASIEFENQESENNDKNLEKL--AQLQIVNNCLEAVKAARDLVIEAKSSPPDNDQ---------MDRAQQASVRXXXXXXXXXXXXPGQRDLDMLSKHIESKKHQFA--ENRLPIQQNNNINLS---NCRSELTDTTFDFNQAVNELVSAPSFNLVNKGCKKMRMSYDRIVE------ICNVLVHDPFDESDSALHHLSSNRDHIANGVMIMSEDCQTLLDKVKKIQCEPDNIIVRKQLQEATKMLLDSINRLLTNISTNLRPGQKECDKTIYRLESMRPILDNPVHPISHKDYFECLDFIIDKTVQPLADSLKNIPAAVKDENNQKFIDSIYHCADSVCMLLEETAQTAYLVGVGDVRSKIGNKGLADHTSFLQIQKEISENCQTICNPDTTARQDSSLMISTAGQIAENSRKLCEASKTIMISFP--NDKIKLSDKTKITLLAVSELMTGVQNL-------NQNFNEDNRKEVESLSGKVQDNVAELVQLLLSY-KFAGDAAIISEEAKESQGPIKAAGITVLDTAIEVIQCSKALIS---SEANEELFIAYSSSCKDLNDALKHLISTIKESAPGQKECDEXXXXXXXXXXQAYDSKMKIMKHRSRTISRTFESEESYQNILQSALIQMPHCINELSRAGKKEPEQLARIFSRQTQLLESMVNSCICAANQTDLIQNSNIYLEHLITILEASEQLLKAVKKSGGNPKANSVHSQIDEMAQGVIESCEDLLAALDKISFKQGNVNTIVETITKSSAKVQESAIIPEKSRFGNSQSKMLDICYDMNNLTTDISSNANSESTQRLLAPLTQNLTQRYDDLCRACQGAVATLSNENNGKQLQECVQTVGKVSISLVKSTTEVR-------------PSVASSISNLQAKTQELHKRIDDVIQLLISSNVGTQACTQAIKILKEINSDIDTSILFVKSADIQ---NDD-------REYYSVKEL-------------------FKKSRNSVIDNSSELVRNIKLIVSKDVCDVNILQESADQIAITSQSLANDVKVGLEHLNSSTSQYNIELLVSFQEVIVSLISFLEVARNTSGLPYTDPLFQNLKEEGKCSINAITSLLKVLKSMDDVNLKDFQAI--------DNAIIXXXXXXXXXXXXXXGISREA--SPVES----PTSTNRLSIGSDITVSPRF-APEEINRLI--PSLANVCDKILEISSPEFKPIIRQENISVVSISCSKVNNELTSACKNLLR-NGPVTDSKKQTLNTVDQLVENYTELLKNFKLYLTNPTKET---RIPVETVVSKLNELIKLLRDQVNLLREGPRLVMYFRPSSPEWRDVSEKYIGRHVAYHHCFVKSYN----HDSHTSLHHHQAPF-IQLPINTRDPSEVDLDT---AKNQIKFVTTKLIDIKLNPDLIGKDKCSVAEVDQMLSYIKDIGWSTEELLSSSQEI--CKSNSDTDNEIWNIDFKKEIFKSAIGVSNAMKDLCEAA---SKPLSTGCSPTWG--------------------DRMSTSTRKVANSTGQLLLNLKP-TVIQNKSQIEKIHTHGNQIKKNTDLL 8016
M+ N + LR+H + VTK + D + T+ Q CE IR +RE+ QT K +GL+LPH+D KKGLWLDN++TL+HYIL+ GDT+EYR R RWL+IRTMDGT K L VDDS +V+ELML +CTK+GIYN++EYSL+ D+ D D++ +++R ++I +DQEK++KLK+K HT+D ++WLNPSQSLRQQGI+E EVLLLKR+YFFSDMNVD+RDP+QL+LLY QLKDA++ GTHPV+L EAI LA +QCQVQ G+Y +KFKP FLDL++ LPKEY K +++EKKIF QH++ LSEV+AK +YC CRS KTYGITFFLVKE++ GKNKLIPRLLGV K+ V+++DE+TKE++ TWPLTSI +WAAS + FTMDFGEYSPD+ YTAQT +GE+ISQLIAGY+DII K++KAKDH G DEES MYEEN+ +A IV+H +P + R K + N +D + S+D D Q IN Q +G R SP + + + + + Q+ ++++ ++++T+Q K+QL I G +G DE S++W+ ++ S+ ++ DE+GAMNAAVAQ LRSA G+ + + + MQ SF ++T+H P+ +++++ A + DQ + V S + L++AA+ +ADAFT+L+++A P+ S +RK I +AA+ VGEAS+DLL+ + + + E + ++TEE++LYQ+ LL LAK+VAN T L+ + K +A + +P Q++V+ AAT+TGL SQL++ TK++APTI Q CQ+QL + +VS A+ VV++S Q ++Q +VQ AA +V++ALD L HL K K D LAYEN+Q+ + +LV++ARRLAQAT MI++I+ +A P+ + +L AAKQLA+ATT LI+ AK C+ + D++ L+ LREA E V+ Y+ A + ++I L AAR T T L+N S A K+SR + ++V +D + ++ I I++I+E+R +P D + Q+ELI AC ++ P E L +S++ + PTVSDP++Q AL+ S Q V A E L+ C+ + + +HL + AL +L RL +I+ S+++ L+PLPDEK ++ LL SV+ ++ + ++ +E ++Q+ + D+ G A L+ A+ LV A RGV A F++ +SE + + A+ + + ++V+ A +LV A + +D + ++Q S +L DALS CL LPG R++ + IE +++ P ++ + S +S+LT +FNQA +L+S+ S + ++ +YD++ + + V P N+D + NG++ +S+ L+ + ++ P+ +R + Q A + + +SI++LLT +T + P ++C+ + RL+++RP+L+NP P++ + Y++C+D + K++ PLADSL+N+ + +D+ Q+F ++ CA+S+C L+EETAQ AYL+G+ D RS+ G L + FL+ Q+EI E C IC+P T RQ MIS + ++A +++ LCEA ++ P + + +L++ T+ T+ +++ L+ N+ N + E NR+ + + V NV+ LV LL + +FAG AA +++EA+ESQ P+ +AG+ L+ A V++ ++ LI+ + +E F +SS+ KDL++++K L S +++ APGQ+EC L + L++ +KM M++ + R +EE +Q L ++ + L RA + E EQL L + ++ I AA+++ L YLEH T+LEA++QL+ + +GGNP+A +H+ +D+ +GV++SCEDLL ALD I+ +QG+V+T+++T+ ++ A+ +E +P +RF + Q+++L I M L I A S++ L PL LTQ Y ++C+ C+GA ATL + + +L+ V+ VG S LV +TT R S I++L + + L ++ ++I LL TQAC Q+ + I +D+DT+ILF S + +DD EY+S EL F R S++ + LV + + +VS D L +A LAN VK G + +ELL + ++V L S + A DP+ ++ + +++ ITSLL+ +K+++D + QA+ D A + G A +PV S P+ N ++ + ++ R+ AP+++ R P + V IL ++ Q ++ + + V +L +A K LLR + +++ + T +L E + ELL K L + RIP T ++ +L L + ++ LREGPRLVMYFR SSPEWRDV+EK+IGRHVAYHH +V +Y+ +H S++ + ++LP T + + T A+++I+ +L +PD KD S +L + + + L+ +++ I ++ + ++++ + VS A + +C+ + S+ L C+ G +R+ RKVA ++ QLL+ K + + ++K+ G +K+ TD L
Sbjct: 45 MVGDNRSLALRVHFPKSGVTKTMVFDAQMTVGQACEHIRAQMRESDQTDGTKDHGLFLPHEDNKKGLWLDNARTLEHYILRNGDTVEYRYRYRWLYIRTMDGTRKKLCVDDSKSVAELMLMICTKMGIYNHEEYSLVREHDENDR----DRSSTLRRQGTGMVTIGRDQEKMEKLKRKLHTDDDMDWLNPSQSLRQQGIDEREVLLLKRRYFFSDMNVDARDPVQLNLLYVQLKDAILKGTHPVSLEEAIRLAAIQCQVQFGDYVPEKFKPNFLDLKDFLPKEYAKL-RSLEKKIFQQHAEMIGLSEVDAKFEYCQFCRSLKTYGITFFLVKERIKGKNKLIPRLLGVTKDKVIRLDERTKEVLKTWPLTSISRWAASLHAFTMDFGEYSPDDCYTAQTSEGEQISQLIAGYVDIITKKQKAKDHAGFQGDEESAMYEENVRAERATIVQHQRMPPTRGP---------RAKDGLLNG-------IADPLISRDMDDSIQMSAVHRINGWSQQHIIGDGMSTVVDGQSIATSGVQPPRQMSPDNFMIGGTHIFHYQEMTPAQRALLVTINEDVETLQAAKEQLQIGPAGERVLLGVGSDETSRRWLSESLGASQAKVTDEMGAMNAAVAQALRSANRAEAYDGIPPAQAGLGASSDPGDDLMMMQQSFRVVTIHFPAFVDDVKRVAVLRREAGAIRADQTGEPTVAEQTEESTQNLLSAARYVADAFTDLLESARPLASGHTREVMDGTDDTATGSHAVITTTTTTTGGPVSSSSRKAIIEAASRVGEASNDLLRHVMNESGDDV---LESTTHLQLLTEEERLYQDHLLSLAKAVANATAGLVVKAKNLATQPNLDPEAQQRVIAAATQTGLCTSQLVACTKVLAPTIHQPSCQQQLSEAAREVSWAVDGVVQASRAVGLTLVDQPPQIQH-SVQMAVTDTETAATEVRDALDALNAHLLKASAKAYSGDALDNFQLAYENLQQ--NHAGGGQRLVASARRLAQATAQMIADIKAQA-ELSGDDPDRQSRLFAAAKQLADATTNLIEVAKVCSANPDDIMLQNELREAAENLNVIAYSA-AAELLHTRLIRSLQAAARATVTGATQLVNVSQVAGKRSRGNPYQVISDAKAVNGMIPRTIISIRESRANPDDPMTQMELIGACERFVQPCEALVRSSRSIAPTVSDPTVQAALDNSTAQLVSAVETLRACLGRLAPLSRHLQIDGALARLARLSVEAAAIETSLQQGTLVPLPDEKVEDCFHLLSMSVQDGSASTRELQSIIEGL-----------AHQDPDIINRPDICGMPATSLASAMAGLVQATRGVVAHEGFDSLDSELSPSMGPAVESARRAVTQDTRQSVQLAYELVKAASDARIASDTHQTATLATVLSHSEQLSAQLLDALSRCLRGLPGHREISEATHLIERRRNDLISLSQSAPTRKVRLVEPSEYERAQSDLTRAAVEFNQATGDLLSSYSPGTFRRTTRRFTGAYDQLTDKGVELSLTGVPCTPPGQP--------QVNQD-LVNGLVTVSDQSHALMTQASRVCARPEEQDLRSRFQAAARDVTESISQLLTICTTGVTPDHRDCEIALRRLDALRPLLENPNRPVNQQAYYDCVDSVA-KSLSPLADSLRNMSNSARDQQTQEFGSAVRQCANSMCQLVEETAQAAYLIGLADPRSEPGKPSLVNTQLFLRTQQEIQEVCDAICSPSVTNRQ----MISLSTEMARSAKVLCEACSSVSAQTPSVDARQQLNNLTRETMQSITALIQHQGNMVNTSGATNGEWAEANRQTTLASAQAVSSNVSRLVHLLTTGPQFAGHAARVTDEARESQVPLCSAGLASLNAAQSVLRAAQNLITNARTSQSEMAFKGFSSASKDLSESIKTLASAMRDHAPGQRECQHVLNNIVHLMQDLQQAKMASMENHLQ--PRRELNEEGFQKQLATSARALLDAAPALGRAARSEAEQLGHAALLVDSYLPGLTSNAIAAASRSPLSSTQLTYLEHACTVLEATDQLVTVARDAGGNPRAAHLHNPLDDAVRGVMDSCEDLLVALDDIASRQGHVSTLIDTLNRALAQTEEIIQVPVDARFSDYQARLLRIARHMEQLNQAIQLRARQPSSEGELTPLAHTLTQEYQEMCQTCKGAAATLPDAHQADELRAAVRAVGLASADLVHATTGSRLRGSDVHGGQQMFLSRNRGIADLDKRAELLDFKLRELIALLDLRGPNTQACLQSASTVSGIIADLDTTILFASSGTLHPPIHDDVDALLSGDEYHSRYELTGPGALDRRGGSGSQSTESFGPIRESIVRTARALVDDTQNLVSGTGEDQARLASTAHTAVERVTQLANVVKRGAAVIGPGQPDTQVELLSACRDVATGLRSVFQSASQLPARTVDDPVVNEVRNNAQLTVSGITSLLQKVKAIEDDERRGLQALILAAKYCRDQASQLAPTTTSAGGDSTTGTETAAILTPVSSRKSAPSVANMSAVSNTSSLIARYLAPDDLARAASGPVQSAVSKAILASNTQS------QGDVLATAAATRDVVTDLVAATKALLRFSEAAPETRSACVVTSRELSEEFAELLDALKATLLPSCRAADRERIPNST--RRIADLSHSLLNLLDTLREGPRLVMYFRASSPEWRDVAEKFIGRHVAYHHHYVPNYSIAGPGFTHRSVYIRPTCYPLRLPHATTEANATADSTEAEAESRIQSAIQQLEHALTSPDESSKDSAS------LLRVAHSVALAAQNLIRTARSIGLVPASEPAERARHAPHRSASLWRTELTVSLATQHMCQLSLLCSEALRAECAAQGGVGKANADELFGTSMRLVPSRERLLAEVRKVAAASAQLLMWAKAHKLTYGANDVQKLQAAGQSVKETTDRL 2877
BLAST of Talin-1 vs. TrEMBL
Match: A0A0X3P9U1 (Uncharacterized protein OS=Schistocephalus solidus OX=70667 GN=TR147538 PE=4 SV=1) HSP 1 Score: 1439.48 bits (3725), Expect = 0.000e+0 Identity = 988/2859 (34.56%), Postives = 1537/2859 (53.76%), Query Frame = 1
Query: 25 PMLNSNGNFELRIHIVDADVTKIVPLDPEATIFQLCETIRKNIREAQT-KSPKSYGLYLPHDDLKKGLWLDNSKTLQHYILKRGDTIEYRNRSRWLHIRTMDGTNKTLKVDDSWTVSELMLTVCTKLGIYNYDEYSLISDKMDFSPGIDKTLSMKR----GISINXXXXXXX-XXXXXYHTEDGLNWLNPSQSLRQQGIEESEVLLLKRKYFFSDMNVDSRDPIQLSLLYEQLKDAVINGTHPVTLPEAIELAGLQCQVQLGNYSADKFKPGFLDLRECLPKEYQKNPKTVEKKIFNQHSKSKDLSEVEAKEKYCLLCRSFKTYGITFFLVKEKVIGKNKLIPRLLGVNKESVVQVDEKTKEIINTWPLTSIRKWAASFNGFTMDFGEYSPDEYYTAQTDKGERISQLIAGYIDIILKRKKAKDHLGVDADEESIMYEENIAPSKAIIVEHVPKQKRSSVSEEDVVIRKKAHMANSSVRMNSQASDSVCSQDCTDFYQED-IN--MSRQTSSLGRTQSPSS-------------------SLTTNSMHYRMSDDDIRQKLYIISLQDNLDTIQKYKDQLMIENKGPE----IGKDEASQQWIYVNIDNSRQRMADEIGAMNAAVAQVLRSAQGLATIXXXXXXXXXXXX------IAKMQNSFSLITVHLPSLMEEIRTAAYYQDQLTDEDVSGEE------------------LIAAAKRLADAFTNLIKAAYPVEDQKRS-------------------LNRKEIFDAANAVGEASSDLLQQITEQENCQIELKSERPYSIIMITEEDQLYQEELLRLAKSVANETTNLIKQVKVIAVEAE-NPSDQKKVVMAATETGLAISQLISTTKIVAPTIEQSVCQEQLIFSIEDVSKAIQVVVESSNKATQS--EELQDLTVQ--------------AANQVQEALDTLMKHLRXXXXXXXXXXXX---XXAYENIQEXXXXXXXXXXXXXXXRRLAQATTAMISEIQLKAVNEQYKTPEERDKLINAAKQLAEATTVLIDSAKNCTMDKDEMNLRYTLREATERFIVVTYTTECATYIQEQVIDHLLVAARKAATTGTHLINTSLSAAKKSRASNFKVCNDGRELSNQISNLIVAIKEARRDPKDHLAQLELIAACRDYIDPSEQLSQSNKYMWPTVSDPSLQTALNQSINQSVIATEELKKCVHQADLMCQHLDLSAALEQLKRLEQNLKSIKNSIERENLIPLPDEKSDESAALLIKSVRRSGSAANQFKNDLESRC---VVYEQTNGEDSYQNLENLDVAGQKARELSMALDRLVHAARGVAASIEFENQESENNDKNLEKLAQLQIVNNCLEAVKAARDLVIEAK-------SSPPDNDQ--MDRAQQASVR-------XXXXXXXXXXXXPGQRDLDMLSKHIESKKH---QFAENRLPIQQN--NNINLSNCRSELTDTTFDFNQAVNELVSAPSFNLVNKGCKKMRMSYDRIVEICNVLVHDPFDESDSALHHLSSNRDHIANGVMIMSEDCQTLLDKVKKIQCEPDNIIVRKQLQEATKMLLDSINRLLTNISTNLRPGQKECDKTIYRLESMRPILDNPVHPISHKDYFECLDFIIDKTVQPLADSLKNIPAAVKDENNQKFIDSIYHCADSVCMLLEETAQTAYLVGVGDVRSKIGNKGLADHTSFLQIQKEISENCQTICNPDTTARQDSSLMISTAGQIAENSRKLCEASKTI--MISFPNDKIKLSDKTKITLLAVSELMTGVQNLNQNFNEDNRKEVESLSGKVQDNVAELVQLLL-SYKFAGDAAIISEEAKESQGPIKAAGITVLDTAIEVIQCSKALISS-----EANEELFIAYSSSCKDLNDALKHLISTIKESAPGQKECDEXXXXXXXXXXQAYDSKMKIMKHRSRTISRTFESEESYQNILQSALIQMPHCINELSRAGKKEPEQLARIFSRQTQLLESMVNSCICAANQTDLIQNSN-IYLEHLITILEASEQLLKAVKKSGGNPKANSVHSQIDEMAQGVIESCEDLLAALDKISFKQGNVNTIVETITKSSAKVQESAIIPEKSRFGNSQSKMLDICYDMNNLTTD---ISSNANSESTQRLLAPLTQNLTQRYDDLCRACQGAVATLSNENNGKQLQECVQTVGKVSISLVKSTTE----------VRPSV--ASSISNLQAKTQELHKRIDDVIQLLISSNVGTQACTQAIKILKEINSDIDTSILFVKSA----------DIQNDDR----EYYSV------------KELFKKSRNSVIDNSSELVRNIKLIVSKDVCDVNILQESADQIAITSQSLANDVKVGLEHLNSSTSQYNIELLVSFQEVIVSLISFLEVARNTSGLPYTDPLFQNLKEEGKCSINAITSLLKVLKSMDDVNLKDFQAIDNAIIXXXXXXXXXXXXXXGISREASPVESPTSTNRLSIGSDI-----TVSPRFAPEEINRLI--PSLANVCDKILEISSPEFKPIIRQENISVVSISCSKVNNELTSACKNLLRNGPVT-DSKKQTLNTVDQLVENYTELLKNFKLYLTNPTKETRIPVETVVSKLNELIKLLRDQVNLLREGPRLVMYFRPSSPEWRDVSEKYIGRHVAYHHCFVKSYNHD----SHTSLHHHQAPFIQLPINTRDP---SEVDLDTAKNQIKFVTTKLIDIKLNPDLIGKDKCSVAEVDQMLSYIKDIGWSTEELLSSSQEICKSNSDTDNEIWNIDFKKEIFKSAIGVSNAMKDLCE-----AASKPLSTGCSPT--------WGDRMSTSTRKVANSTGQLLLNLKPTVIQNKSQIEKIHTHGNQIKKNTD 8010
PM + LRIH+ DADVTK + D T+ Q C+ IR+ IRE +PK YGL+LPH+D KKGLWLD+S++L+HYIL+ GDT+EY+ R RWL+IRTMDGT KTL+VDDS T+SELML +CTK+GIYNY+EY L+ D + D+T+++++ G+S + KL+++ HT+D + WLNPSQSLRQQGI E E+LLL+R+YFFSDMNVD+RDP+QL+LLY QLKDA++NGTHPVTL EA+ LA +QCQV+LGNY+ +KFK GFLDL++ LPKE+ K K +EKKIF QH+ +S+VEA+ KYC CRS KTYGITFFLVKEK+ GKN+LIPRLLG+ ++SVV++DE+TKE++ WPLTSI KWAAS N FTMDFGEYSPDEYYTAQT +GE+ISQLIAGYIDIILK++KA+DH G+ DEES MYEEN+ +A IV+ R SV D R + N++ S+ DS + + Y D +N M L +SP S + T++ HY+ Q+ ++++ +N++ +++ K L I + IG DEAS++W+ ++ S+ ++AD++GAMNAAVAQ +RSA + + MQ SF ++TVH P+ +++++ A + + EE L+ AA+ +AD+F+ L+KAA P+ Q+++ +RK I +AAN VGEAS+D L+ + + Q + + EE++ YQ+ELL LAK VAN T L+ + K +A + +P Q+ VV AAT+TGL SQL++ TK++APTI Q CQ+QL S +VS A+ VV+++ A QS ++ Q+L+ + AA +V+ LD L HL K+ + + DN AYE +Q + D ++V+AARRL+Q + MI++++ +A + PE + KL AAKQLA+ATT LI+ AK C+ D + L+++ + +VV Y + A + +V+ L AAR T THL+NTS AAKKSRA+N+ + D R ++ L+ AI+ R P D LAQLELI AC+ ++P L++S++ M PTVSDPSLQ+ L S++Q V+A E L+ C+ +A + + L + AL +L RL + + ++S +L LPD+K ++ +L VR A NQ +ES VY +G D + D G + +L+ AL LV A R +AA+ K + + +++C+ + + A LV E++ S P+ + R + + + L+ AL+ CL LPGQR++ S ++ ++H +FAE+ I+ + + I+ ++ R++ T +FNQA EL S + N + + +YD +V+ L E + I N ++ +S+ + LL+ +++ EP+ +R +L A K + DSIN LL ++ L PG +CD + RLE++RP+L+ P PI+ Y EC++ + TV PLAD L+ I AV + N KF + DS+C+L+EETAQ AYL+G+ +SK G K D F IQ+EI + C+ I +P T RQD + ++S A I+ N R LC+A +I + ++ +L T+ + +++EL+ + +++E+ ++ + + V +V++LV+ + +FAG A I+ EA+ESQ P+ AGI+ LD V+ SK +++S E+ + F+ +S++ DL+D +KHL+S +K APGQ EC +AL +A+L++ +M IM R R + E +Q L +++ + L RA E E+L LL +V+S + +A++ S IYL H T+LE+SEQL+ A K++GGNP++ +H+ I++ + IESCEDLL+A+D I + + ++ + +S + V + A +P + F + Q++ML + M T +S A++ + L P+ NL Q Y +LC C+ A TL + QL+ V+ VG + +L++S T R V +SS NL ++ R+ ++I LL + GTQAC Q + I +D+DT+ILF S D+ N DR E +S+ ++ F R S+ + LV + + +VS D N L S LA VK G L + LL +E VS+ + A G DP++++L+ G N+ L+ + S+D + + +A+ A + G AS VE ++ N+ S + VS APEE++R + P V +L SS +Q++ + + +L ACK L+R V+ ++++ T + V Q+ + +LL K + ++ R + ++ L L + L+EGPRLVMYFR SSPEWRDV+EK++GRHVA+HH +V Y D + T + HQ +Q+ +++ E A+ +I +L D LN ++ + V +LS K I + E + + + +T + + +S + VS A + LCE +AS+P +P +R+ + R+VA+++ +LL + +++ + G +K+ TD
Sbjct: 10 PMTGDSRRLALRIHVPDADVTKTLVFDALMTVGQACDQIRQQIREIDGLDNPKDYGLFLPHEDSKKGLWLDHSRSLEHYILRNGDTVEYKYRYRWLYIRTMDGTRKTLRVDDSKTLSELMLPICTKMGIYNYEEYLLVRDVDEAEK--DRTMTLRKSHQTGMSGTLRDAEKMDKLRRELHTDDDVTWLNPSQSLRQQGIGEKEILLLRRRYFFSDMNVDARDPVQLNLLYVQLKDAILNGTHPVTLDEAVYLAAIQCQVELGNYNPEKFKSGFLDLKDFLPKEFLK-VKGLEKKIFQQHATLNGISDVEARVKYCHFCRSLKTYGITFFLVKEKMKGKNRLIPRLLGITRDSVVRLDERTKEVVKVWPLTSILKWAASPNAFTMDFGEYSPDEYYTAQTSEGEQISQLIAGYIDIILKKQKARDHQGLQGDEESAMYEENVRAERAKIVQSA----RRSVGPAD---RDR----NAATDGVSETIDSQRVETQMNGYTGDQLNGYMGTTERHLITLESPVSIDGQSVVSRQRNDNQDDFMTGGTHTYHYQTMTP--VQRALMLTIDENMEVLEQGKQMLDIGSPSERVLLNIGHDEASKRWLDESMGASQVKVADDVGAMNAAVAQAVRSANRADAVLSQTAGYEVGAGSDPGDDLMMMQQSFRVVTVHFPAFVDDVKRVAVLRRETGALQAEAEENPETREYITMRAENSAQNLLGAARTVADSFSELLKAATPLATQQQTDYEISSTVQYSDHAVPVGGSSRKAILEAANRVGEASNDFLRFVIQDGEEQAMATDDTGTGLRSFAEEERAYQDELLGLAKEVANATAGLVVKAKHLATQTNLDPEHQQDVVFAATQTGLCTSQLVACTKVLAPTIRQPTCQQQLSESAREVSVAVDGVVKAARGAGQSVYDQQQNLSPEESAEVNEAVRDVDDAATEVRNTLDRLNAHLLKESVRPYRGDNLDLFQAAYEALQR----ETDGQRMVAAARRLSQVSAQMIADVKTQA-EQADGDPERQTKLFAAAKQLADATTDLINHAKVCSTAPDSEPNQTKLKQSADELVVVAYAS-AAELLNARVMRSLQAAARAVVTASTHLVNTSRCAAKKSRANNYHILEDARVVNELTPKLVAAIRYVRSHPDDPLAQLELICACQQVVEPCSILARSSRSMAPTVSDPSLQSTLELSMSQMVVAVETLRACLGRAAPIARQLQMDGALARLLRLIRESEETESSARAGSLTALPDDKVEDRFQMLSLGVRDGIDAGNQIGAAVESLTSAYSVYPSASGRDQEE-----DWLGSSSNQLASALADLVQATRCIAAA-------DMATTKGVAGEVLTEFLHSCVLSTQIAYQLVCESRKLEVLEPSQTPETQAALLQRNTEVNTKCRDYITDLTAALTGCLRGLPGQREISEASIMVKRRRHDLVRFAEDPTIIEFHDADQISPADTRTDFTGAAVEFNQATVELTSCYTPNNFKRSSLRFAGAYDNLVDRGLRLSRSKPPEDITG--------KEIVNELVQISDKSEILLEDAQQVCNEPEIQPLRNRLHSAAKSVTDSINHLLNLSTSGLAPGATDCDAALRRLEALRPLLEQPTRPINQHIYHECIETVAQSTV-PLADGLRGISNAVNENNADKFSVHVQQTTDSICLLIEETAQAAYLIGIAHPKSKPGTKSPVDRALFEGIQREIQDACKAITSPQVTERQDRARVVSLANDISSNLRTLCDACTSISAQATSAEERRQLKTLTQDMMQSITELV----KRSADWSEEGKRATANNAHLVNTHVSQLVRFVTCGPQFAGHPARITAEARESQQPLCTAGISCLDAGKSVLIASKHMVNSAQTKNESADSSFMNFSAASHDLSDGIKHLVSVLKSHAPGQAECQQALENIARLLRDLQRDEMAIMD--DRFPQRHDNTAEGFQKQLTTSVRAVMEMAPTLGRAATSEAERLGHSVRELDALLPGIVSSALGSASRAPPGCPSQLIYLGHTRTLLESSEQLVLAAKEAGGNPRSVHLHAPIEDAVRAQIESCEDLLSAVDSIVSQHDFMEKLMAVLNQSQSVVDQPARVPRDAHFTDYQARMLRLARHMEQQTQSAVIVSRRADATAE---LPPVANNLAQDYAELCLVCRDASETLPDGRQSDQLRSAVKNVGNATRALIQSATSGAFARTRDGPGRQLVEESSSQRNLDYAAGLMNDRLRELIALLEAQGPGTQACLQGASTVSGIIADLDTTILFASSGTLHPPIHDDFDVANLDRRRAGERFSLTIRGADDFGHEAQDNFISIRESINRAADALVEDTRSLVSGAGEDQNRLAGSTHLAVRNISQLAEVVKQGASILGPGQLDNQVALLEGAKETAVSVRTLFLTASQLHGRQKPDPVYEDLRLSGDAVQNSAAKLVTLANSIDSESTRGTKALIAA--TKFCHQMADHVSTMGAELSASQVEMNSAVNQCGSASTLLSTTSLVSRYMAPEELSRAVAGPMQLVVSKAVLASSSR------KQDDGLTAANTARHALIDLVQACKGLVRQQEVSKEARQSTKSAVKQIASEFAKLLDGVKCVIHADNEKDRERISLAAGRIAALSSQLLNIAEGLKEGPRLVMYFRASSPEWRDVAEKFLGRHVAFHHHYVPCYGKDGSSVTSTRVASHQTSCLQMRLDSVGRVVVGEGASSEAEKRIDAALQRLED-GLNRART-HEQATTPSVQPILSMTKSIALAAREFIQAVR-TSSGAGETPKTSRSGSETATLGRSELSVSVATEYLCELARFCSASRPEGPTAAPVDDPVKIMPSRERLLAAIRQVASTSAELLYAARSRRQLPPTRLSAVQATGKAVKEQTD 2805
BLAST of Talin-1 vs. TrEMBL
Match: A0A5K4FCV3 (Putative talin OS=Schistosoma mansoni OX=6183 PE=4 SV=1) HSP 1 Score: 1435.62 bits (3715), Expect = 0.000e+0 Identity = 949/2696 (35.20%), Postives = 1502/2696 (55.71%), Query Frame = 1
Query: 28 MLNSNGNFELRIHIVDADVTKIVPLDPEATIFQLCETIRKNIREA-QTKSPKSYGLYLPHDDLKKGLWLDNSKTLQHYILKRGDTIEYRNRSRWLHIRTMDGTNKTLKVDDSWTVSELMLTVCTKLGIYNYDEYSLISDKMDFSPGIDKTLSMKRGI-------SINXXXXXXXXXXXXYHTEDGLNWLNPSQSLRQQGIEESEVLLLKRKYFFSDMNVDSRDPIQLSLLYEQLKDAVINGTHPVTLPEAIELAGLQCQVQLGNYSADKFKPGFLDLRECLPKEYQKNPKTVEKKIFNQHSKSKDLSEVEAKEKYCLLCRSFKTYGITFFLVKEKVIGKNKLIPRLLGVNKESVVQVDEKTKEIINTWPLTSIRKWAASFNGFTMDFGEYSPDEYYTAQTDKGERISQLIAGYIDIILKRKKAKDHLGVDADEESIMYEENIAPSKAIIVEH--VPKQKRSSVSEEDVVIRKKAHMANSSV--------RMNSQASDSVCSQDCTDFYQED-----------INMSRQTSSLGRTQSPSSSLTTNSMHYRMSDDDIRQKLYIISLQDNLDTIQKYKDQLMIENKGP-------EIGKDEASQQWIYVNIDNSRQRMADEIGAMNAAVAQVLRSAQGLATIXXXXXXXXX--------XXXIAKMQNSFSLITVHLPSLMEEIRTAAYYQDQ--LTDEDVSGEELIA------------AAKRLADAFTNLIKAA------------YPVEDQK---------------RSLNRKEIFDAANAVGEASSDLLQQITEQENCQIELKSERPYSIIMITEEDQLYQEELLRLAKSVANETTNLIKQVKVIAVE-AENPSDQKKVVMAATETGLAISQLISTTKIVAPTIEQSVCQEQLIFSIEDVSKAIQVVVESSNKATQ--SEELQDL------TVQAANQVQEALDTLMKHL---RXXXXXXXXXXXXXXAYENIQEXXXXXXXXXXXXXXXRRLAQATTAMISEIQLKAVNEQYKTPEERDKLINAAKQLAEATTVLIDSAKNCTMDKDEMNLRYTLREATERFIVVTYTTECATYIQEQVIDHLLVAARKAATTGTHLINTSLSAAKKSRASNFKVCNDGRELSNQISNLIVAIKEARRDPKDHLAQLELIAACRDYIDPSEQLSQSNKYMWPTVSDPSLQTALNQSINQSVIATEELKKCVHQADLMCQHLDLSAALEQLKRLEQNLKSIKNSIERENLIPLPDEKSDESAALLIKSVRRSGSAANQFKNDLESRCVVYEQTNGEDSYQNLENLDVAGQKARELSMALDRLVHAARGVAAS-----IEFENQESENNDKNLEKLAQLQIVNNCL----EAVKAARDLVIEAKSSPPDNDQM--DRAQQASVRXXXXXXXXXXXXPGQRDLDMLSKHIESKKHQFAENRLPIQQNNNINLS----------NCRSELTDTTFDFNQAVNELVSAPSFNLVNKGCKKMRMSYDRIVE------ICNVLVHDPFDESDSALHHLSSNRDHIANGVMIMSEDCQTLLDKVKKIQCEPDNIIVRKQLQEATKMLLDSINRLLTNISTNLRPGQKECDKTIYRLESMRPILDNPVHPISHKDYFECLDFIIDKTVQPLADSLKNIPAAVKDENNQKFIDSIYHCADSVCMLLEETAQTAYLVGVGDVRSKIGNKGLADHTS------------------FLQIQKEISENCQTICNPDTTARQDSSLMISTAGQIAENSRKLCEASKTIMISFPN--DKIKLSDKTKITLLAVSELM-----TGVQNLNQNFNEDNRKEVESLSGKVQDNVAELVQLLLSYKFAGDAAI----ISEEAKESQGPIKAAGITVLDTAIEVIQCSKALISSE---ANEELFIAYSSSCKDLNDALKHLISTIKESAPGQKECDEXXXXXXXXXXQAYDSKMKIMKHRSRTISRTFESEESYQNILQSALIQMPHCINELSRAGKKEPEQLARIFSRQTQLLESMVNSCICAANQTDLIQNSNIYLEHLITILEASEQLLKAVKKSGGNPKANSVHSQIDEMAQGVIESCEDLLAALDKISFKQGNVNTIVETITKSSAKVQESAIIPEKSRFGNSQSKMLDICYDMNNLTTDISSNANSESTQRLLAPLTQNLTQRYDDLCRACQGAVATLSNENNGKQLQECVQTVGKVSISLVKSTTEVRPSVAS----------------SISNLQAKTQELHKRIDDVIQLLISSNVGTQACTQAIKILKEINSDIDTSILFVKSAD----IQND------DREYYSVK---------------------------------ELFKKSRNSVIDNSSELVRNIKLIVSKDVCDVNILQESADQIAITS-QSLANDVKVGLEHLNSSTSQYNIELLVSFQEVIVSLISFLEVARNTSGLPYTDPLFQNLKEEGKCSINAITSLLKVLKSMDDVNLKDFQAIDNA--IIXXXXXXXXXXXXXXGISREASPVESPTSTNRLSIGSDITVSPRFAPEEINRLI--PSLANVCDKILEISSPEFKPIIRQENISVVSISCSKVNNELTSACKNLLRNGPVTDSKKQTLNTVD-QLVENYTELLKNFKLYLTNPTKETRIPVETVVSKLNELIKLLRDQVNLLREGPRLVMYFRPSSPEWRDVSEKYIGRHVAYHHCFVKSY 7452
ML + + LR+H+ A +TK D + T+ Q CE IR +RE+ QT K YGL+LPH+D KKGLWLDNS+TL+HYIL+ GDTIEYR R RWL+IRTMDGT KTLKVDDS TV+ELML +CTK+GIYNY+EY L D+ + ++T ++KR ++ +DQEK++KLK+K HT+D + WLNPSQSLRQQG++E E+LLLKR+YFFSDMNVD+RDP+QL+LLY QLKDA++ GTHPV+L EA+ LAG+QCQVQ GNY A+KFKP FLDL++ LPKEY K +++EKKIF QH++ LSE+EAK KYC CRS KTYGITFFLVKE++ GKNKLIPRLLG+ K+SVV++DEKTKE++ WPLTSI KWAAS + FTMDFGEYSPDEYYTAQT +GE+ISQLIAGYIDIILK++KA DH G+ DEES MYEEN+ +A IV+H VP V +R K + N V N AS + + +Q++ S T++ R SP + +T + + + QK +I++ ++L+T+Q K+ L I GP +G DEAS++W+ ++ S+ ++ DE+GAMNAAVAQ LRSA + + + ++ + + MQ SF ++T+H P+ +++++ A + + D +G+ +IA AA+ +ADAFT+L+++A YP D S +RK I +AA+ VG AS+DLL+ + + + + +++T+E+++YQ++LL LAK+VAN T L+ + KV+A + +P Q++V+ + T+TGL SQL++ TK++APTI Q CQ+QL + +V+ A+ VV++S A SE+ Q + T AA +V++ALD L HL + D L++F +YE++++ D ++V++ARRLAQAT MI++I+ +A E + +++L +AAKQLA+ATT LI++AK C+ + D + L+ LR+A + + Y+ + Q ++I +L AAR T T L+N S +A K SR +++++ ND R ++N I ++ I+E+R +P D +A LELI AC ++ P + +S+K + PT+SDPS+Q AL S +Q A E L C+ + +HL L AL +L RL + I+ S+ + L P+P++K ++ L+ SV +A + + + S + DS L ++AGQ A L+ A+ LVHA RG+ A I N + + + A +Q + + E V+A +D I + P N +QQ + +L + L+ CL LPG R++ + IE K+ Q + P N INL+ +++LT +FNQA +L+S+ S + ++ +YD + + ICN + S++ N D + NG++ +S+ L+++ ++ +P+ +R + Q A + + +SI++LLT ++ + P Q+EC+ I RL+S RP+L NP P++ Y++C+D + K+++PLA+SL+ + + +D+ +F ++ CA+SVC L+EETAQTAYL+G+ D +I N+ ++ TS F+Q QKEI C IC P+ RQ +IS + ++A +++ LCEA + N + +L++ TK T+ +++ L+ T ++N ++E NR++ + + V NVA LV+L+ + D I+ KE+Q P+ AG+ L+ V++ ++ L+S+ +E F+A+SS+ KDL++++K L + ++E+APGQ+EC + KL+ + D+++ M++ R R +EE +Q + +++ + + RA E EQL R L +V+ I AA+++ L +YL+H T+LEA+ QL+ K SGGNP+A +H ++E +G+++SCE+ L LD ++ +QG+V+T+++T+ ++ A+ +E +P +RF + Q++ML I M+ L I A ++ +APL NLTQ Y ++C+ C+GA ATL + N QL+ V+ VG ISL+++T+ RP + SI L + + L ++ ++I LL GTQAC Q+ + I SD+DT+ILF S +++D D E+ + E F R S+ + LV + + +VS D L +A IA+ LA+ VK G + +ELL S ++V +L S + G P DP++ ++ + I+ + LL+ LKS+++ + ++++ A + + G+ S +S + ++ GS ++ AP+++ R P + V IL ++ + I++ S + +L +A K LLR + + + V +L E + LL K L P K V + ++ ++ L + V+ LREGPRL+MYFR SSPEWRDV+EK+IGRHVAYHH +V +Y
Sbjct: 1 MLGDSRSLVLRVHLPKAGITKTTAFDAQMTVGQACERIRAQVRESDQTDGAKDYGLFLPHEDNKKGLWLDNSRTLEHYILRNGDTIEYRYRYRWLYIRTMDGTRKTLKVDDSKTVAELMLMICTKMGIYNYEEYLLARDRDETDR--ERTNTLKRSTGHHHHTGTLMRDQEKMEKLKRKLHTDDDMEWLNPSQSLRQQGVDEKEILLLKRRYFFSDMNVDARDPVQLNLLYVQLKDAILKGTHPVSLEEAVYLAGIQCQVQFGNYVAEKFKPNFLDLKDFLPKEYAK-IRSLEKKIFQQHAELCGLSEIEAKVKYCQFCRSLKTYGITFFLVKERIKGKNKLIPRLLGITKDSVVRLDEKTKEVLKIWPLTSICKWAASPHAFTMDFGEYSPDEYYTAQTSEGEQISQLIAGYIDIILKKQKATDHPGLQGDEESAMYEENVQAERATIVQHQRVP-----------VRVRGKDQLVNGVVEKPFDHHQHRNDLASHQIHTNGVWSIHQQNNLVGDENSTVIDGQSILTATTTRQMSPDNFMTGGTHIFHYQEMSPAQKSLLITINEDLETLQAAKEHLDI---GPPTERHLLNVGTDEASKRWLSESMGASQAKVTDEVGAMNAAVAQALRSANRAESTDINAVQQGQPLDQIHDPGDDLMMMQQSFRVVTIHFPAFVDDLKRVAVLRRESGALKADQTGQPIIAEKTEESTQNLLSAARHVADAFTDLLQSARPLAMGQTHEEIYPTSDDGTYQANHVITQQQGPVSSSSRKAIIEAASRVGAASNDLLRHVMHGGDDDDLFNT----NYLILTDEERIYQDQLLGLAKAVANATAGLVVKAKVLASQITSDPEAQQRVIASVTQTGLCTSQLVACTKVLAPTIHQPTCQQQLSEAGREVTWAVDGVVQASRAAVHVPSEDPQMVQQSIIETETAATEVRDALDQLNAHLLKGSYKGYQGDALNSFQTSYEDLKQ--YYTTDGQRMVASARRLAQATALMIADIKAQA-EESGDDSDRQNRLFHAAKQLADATTNLINAAKACSSNPDNIQLQTELRDAADELYTLAYSAGGEQF-QTRLIHNLQSAARATVTGATQLVNISQAATKYSRGNSYQLHNDTRNVTNLIPKTVITIRESRANPDDPMALLELIGACERFVQPCTAMVRSSKSLAPTLSDPSIQAALENSNSQLASALETLITCLIKVAPFARHLQLDGALTRLTRLSDEVAEIETSLMQGTLTPIPEQKVEDCCHLVNISVHDGTESAKKLDSIINSMAKM-------DSAV-LNQPELAGQSADRLASAMTGLVHATRGIIADQNSLIINGSNSNNNTSAAESTRRAVIQDIRQAVQLSYELVRAVKDTRIACDAKQPANAATVQSHSQQLTTQLIETLTRCLRGLPGHREISEATYLIEQKRSQLIQYSQP----NQINLTARFVEPNEYQRKQTDLTQAAVEFNQATGDLLSSYSPGSFKRTTRRFTGAYDCLTDKGIELSICNEI------PSNNQQFEPVVNTD-LLNGLINVSDQSYVLMNEASRVCGQPEAENLRGKFQSAARDVTESISQLLTICTSGVSPDQRECEAAIRRLDSFRPLLLNPNRPLNQHSYYDCVD-TVAKSLEPLAESLRTMSTSARDQKLNEFSFAVRQCANSVCQLVEETAQTAYLIGLAD---RIENRRVSGATSISSGISSPPGSSLIDLDLFIQSQKEIQSACNAICEPNVNNRQ----VISLSTEMARSAKTLCEACSQLASQTTNVDTRQRLNNITKQTMQSITSLIQHRGSTVATDVNGEWSESNRQQTLANAQAVSANVANLVKLITTEPRLVDLTTSQERITNTTKETQRPVCVAGLESLNATQTVLRAAQNLLSTSRMGPSENTFMAFSSASKDLSNSIKVLANAMRENAPGQRECQCVFNNIKKLLHELQDARIASMEN--RLPPRRELNEEGFQRQVATSVRALLDSAPAVGRAASSEAEQLGRTILTWDFYLPGLVSGSIAAASRSPLSSTQLVYLDHACTVLEAASQLVTVAKDSGGNPRAVHLHDSLNESVRGLVDSCEEFLTILDDVASRQGHVSTLIDTLNRAQAQAEEIIQVPMDARFSDYQTRMLRIARHMDQLNQAIQLRARQPASDGEIAPLAHNLTQEYQEMCQTCKGAAATLPDVNQADQLRSAVRGVGTACISLIQATSASRPDIYGSGTTTGGQHLLLTRNKSIVELDRRAEFLDSKLRNLINLLEIHGPGTQACLQSASTVSGIISDLDTTILFASSGTLHPPVRDDFDAIWTDNEFGHSRLTADRGHSLALSNNTDGTSIPSRAGSRSEMHNVENFTPLRESIARTARALVDDTQSLVSGTGEDQARLANTA-HIAVERITELADVVKRGAAVIGPGQPDTQVELLTSCRDVATALRSVFLSSGKVQGRPSLDPIYDEVRSNAQVVISNVGQLLQTLKSVEEDERRGIRSLELAANYCREQAKLLPSSKDPEGLLTPNSSRKSGPRSTSVASGSSSLIARYLAPDDLARAAGGPVQSAVSKAILANNTQIHRDIVQ------TSSATRDAVADLVAAAKCLLRYSDIPPETRSSCAIVTRELAEEFAALLDALKNGLYIPRKSGPENVSNIARRIADISHSLINLVDSLREGPRLIMYFRASSPEWRDVAEKFIGRHVAYHHHYVSNY 2635
BLAST of Talin-1 vs. TrEMBL
Match: A0A0X3PHC1 (Uncharacterized protein OS=Schistocephalus solidus OX=70667 GN=TR147538 PE=4 SV=1) HSP 1 Score: 1431 bits (3703), Expect = 0.000e+0 Identity = 987/2859 (34.52%), Postives = 1535/2859 (53.69%), Query Frame = 1
Query: 25 PMLNSNGNFELRIHIVDADVTKIVPLDPEATIFQLCETIRKNIREAQT-KSPKSYGLYLPHDDLKKGLWLDNSKTLQHYILKRGDTIEYRNRSRWLHIRTMDGTNKTLKVDDSWTVSELMLTVCTKLGIYNYDEYSLISDKMDFSPGIDKTLSMKR----GISINXXXXXXX-XXXXXYHTEDGLNWLNPSQSLRQQGIEESEVLLLKRKYFFSDMNVDSRDPIQLSLLYEQLKDAVINGTHPVTLPEAIELAGLQCQVQLGNYSADKFKPGFLDLRECLPKEYQKNPKTVEKKIFNQHSKSKDLSEVEAKEKYCLLCRSFKTYGITFFLVKEKVIGKNKLIPRLLGVNKESVVQVDEKTKEIINTWPLTSIRKWAASFNGFTMDFGEYSPDEYYTAQTDKGERISQLIAGYIDIILKRKKAKDHLGVDADEESIMYEENIAPSKAIIVEHVPKQKRSSVSEEDVVIRKKAHMANSSVRMNSQASDSVCSQDCTDFYQED-IN--MSRQTSSLGRTQSPSS-------------------SLTTNSMHYRMSDDDIRQKLYIISLQDNLDTIQKYKDQLMIENKGPE----IGKDEASQQWIYVNIDNSRQRMADEIGAMNAAVAQVLRSAQGLATIXXXXXXXXXXXX------IAKMQNSFSLITVHLPSLMEEIRTAAYYQDQLTDEDVSGEE------------------LIAAAKRLADAFTNLIKAAYPVEDQKRS-------------------LNRKEIFDAANAVGEASSDLLQQITEQENCQIELKSERPYSIIMITEEDQLYQEELLRLAKSVANETTNLIKQVKVIAVEAE-NPSDQKKVVMAATETGLAISQLISTTKIVAPTIEQSVCQEQLIFSIEDVSKAIQVVVESSNKATQS--EELQDLTVQ--------------AANQVQEALDTLMKHLRXXXXXXXXXXXX---XXAYENIQEXXXXXXXXXXXXXXXRRLAQATTAMISEIQLKAVNEQYKTPEERDKLINAAKQLAEATTVLIDSAKNCTMDKDEMNLRYTLREATERFIVVTYTTECATYIQEQVIDHLLVAARKAATTGTHLINTSLSAAKKSRASNFKVCNDGRELSNQISNLIVAIKEARRDPKDHLAQLELIAACRDYIDPSEQLSQSNKYMWPTVSDPSLQTALNQSINQSVIATEELKKCVHQADLMCQHLDLSAALEQLKRLEQNLKSIKNSIERENLIPLPDEKSDESAALLIKSVRRSGSAANQFKNDLESRC---VVYEQTNGEDSYQNLENLDVAGQKARELSMALDRLVHAARGVAASIEFENQESENNDKNLEKLAQLQIVNNCLEAVKAARDLVIEAK-------SSPPDNDQ--MDRAQQASVR-------XXXXXXXXXXXXPGQRDLDMLSKHIESKKH---QFAENRLPIQQN--NNINLSNCRSELTDTTFDFNQAVNELVSAPSFNLVNKGCKKMRMSYDRIVEICNVLVHDPFDESDSALHHLSSNRDHIANGVMIMSEDCQTLLDKVKKIQCEPDNIIVRKQLQEATKMLLDSINRLLTNISTNLRPGQKECDKTIYRLESMRPILDNPVHPISHKDYFECLDFIIDKTVQPLADSLKNIPAAVKDENNQKFIDSIYHCADSVCMLLEETAQTAYLVGVGDVRSKIGNKGLADHTSFLQIQKEISENCQTICNPDTTARQDSSLMISTAGQIAENSRKLCEASKTI--MISFPNDKIKLSDKTKITLLAVSELMTGVQNLNQNFNEDNRKEVESLSGKVQDNVAELVQLLL-SYKFAGDAAIISEEAKESQGPIKAAGITVLDTAIEVIQCSKALISS-----EANEELFIAYSSSCKDLNDALKHLISTIKESAPGQKECDEXXXXXXXXXXQAYDSKMKIMKHRSRTISRTFESEESYQNILQSALIQMPHCINELSRAGKKEPEQLARIFSRQTQLLESMVNSCICAANQTDLIQNSN-IYLEHLITILEASEQLLKAVKKSGGNPKANSVHSQIDEMAQGVIESCEDLLAALDKISFKQGNVNTIVETITKSSAKVQESAIIPEKSRFGNSQSKMLDICYDMNNLTTD---ISSNANSESTQRLLAPLTQNLTQRYDDLCRACQGAVATLSNENNGKQLQECVQTVGKVSISLVKSTTE----------VRPSV--ASSISNLQAKTQELHKRIDDVIQLLISSNVGTQACTQAIKILKEINSDIDTSILFVKSA----------DIQNDDR----EYYSV------------KELFKKSRNSVIDNSSELVRNIKLIVSKDVCDVNILQESADQIAITSQSLANDVKVGLEHLNSSTSQYNIELLVSFQEVIVSLISFLEVARNTSGLPYTDPLFQNLKEEGKCSINAITSLLKVLKSMDDVNLKDFQAIDNAIIXXXXXXXXXXXXXXGISREASPVESPTSTNRLSIGSDI-----TVSPRFAPEEINRLI--PSLANVCDKILEISSPEFKPIIRQENISVVSISCSKVNNELTSACKNLLRNGPVT-DSKKQTLNTVDQLVENYTELLKNFKLYLTNPTKETRIPVETVVSKLNELIKLLRDQVNLLREGPRLVMYFRPSSPEWRDVSEKYIGRHVAYHHCFVKSYNHD----SHTSLHHHQAPFIQLPINTRDP---SEVDLDTAKNQIKFVTTKLIDIKLNPDLIGKDKCSVAEVDQMLSYIKDIGWSTEELLSSSQEICKSNSDTDNEIWNIDFKKEIFKSAIGVSNAMKDLCE-----AASKPLSTGCSPT--------WGDRMSTSTRKVANSTGQLLLNLKPTVIQNKSQIEKIHTHGNQIKKNTD 8010
PM + LRIH+ DADVTK + D T+ Q C+ IR+ IRE +PK YGL+LPH+D KKGLWLD+S++L+HYIL+ GDT+EY+ R RWL+IRTMDGT KTL+VDDS T+SELML +CTK+GIYNY+EY L+ D + D+T+++++ G+S + KL+++ HT+D + WLNPSQSLRQQGI E E+LLL+R+YFFSDMNVD+RDP+QL+LLY QLKDA++NGTHPVTL EA+ LA +QCQV+LGNY+ +KFK GFLDL++ LPKE+ K K +EKKIF QH+ +S+VEA+ KYC CRS KTYGITFFLVKEK+ GKN+LIPRLLG+ ++SVV++DE+TKE++ WPLTSI KWAAS N FTMDFGEYSPDEYYTAQT +GE+ISQLIAGYIDIILK++KA+DH G+ DEES MYEEN+ +A IV+ R SV D R + N++ S+ DS + + Y D +N M L +SP S + T++ HY+ Q+ ++++ +N++ +++ K L I + IG DEAS++W+ ++ S+ ++AD++GAMNAAVAQ +RSA + + MQ SF ++TVH P+ +++++ A + + EE L+ AA+ +AD+F+ L+KAA P+ Q+++ +RK I +AAN VGEAS+D L+ + + Q + + EE++ YQ+ELL LAK VAN T L+ + K +A + +P Q+ VV AAT+TGL SQL++ TK++APTI Q CQ+QL S +VS A+ VV+++ A QS ++ Q+L+ + AA +V+ LD L HL K+ + + DN AYE +Q + D ++V+AARRL+Q + MI++++ +A + PE + KL AAKQLA+ATT LI+ AK C+ D + L+++ + +VV Y + A + +V+ L AAR T THL+NTS AAKKSRA+N+ + D R ++ L+ AI+ R P D LAQLELI AC+ ++P L++S++ M PTVSDPSLQ+ L S++Q V+A E L+ C+ +A + + L + AL +L RL + + ++S +L LPD+K ++ +L VR A NQ +ES VY +G D + D G + +L+ AL LV A R +AA+ K + + +++C+ + + A LV E++ S P+ + R + + + L+ AL+ CL LPGQR++ S ++ ++H +FAE+ I+ + + I+ ++ R++ T +FNQA EL S + N + + +YD +V+ L E + I N ++ +S+ + LL+ +++ EP+ +R +L A K + DSIN LL ++ L PG +CD + RLE++RP+L+ P PI+ Y EC++ + TV PLAD L+ I AV + N KF + DS+C+L+EETAQ AYL+G+ +SK G K D F IQ+EI + C+ I +P T RQ ++S A I+ N R LC+A +I + ++ +L T+ + +++EL+ + +++E+ ++ + + V +V++LV+ + +FAG A I+ EA+ESQ P+ AGI+ LD V+ SK +++S E+ + F+ +S++ DL+D +KHL+S +K APGQ EC +AL +A+L++ +M IM R R + E +Q L +++ + L RA E E+L LL +V+S + +A++ S IYL H T+LE+SEQL+ A K++GGNP++ +H+ I++ + IESCEDLL+A+D I + + ++ + +S + V + A +P + F + Q++ML + M T +S A++ + L P+ NL Q Y +LC C+ A TL + QL+ V+ VG + +L++S T R V +SS NL ++ R+ ++I LL + GTQAC Q + I +D+DT+ILF S D+ N DR E +S+ ++ F R S+ + LV + + +VS D N L S LA VK G L + LL +E VS+ + A G DP++++L+ G N+ L+ + S+D + + +A+ A + G AS VE ++ N+ S + VS APEE++R + P V +L SS +Q++ + + +L ACK L+R V+ ++++ T + V Q+ + +LL K + ++ R + ++ L L + L+EGPRLVMYFR SSPEWRDV+EK++GRHVA+HH +V Y D + T + HQ +Q+ +++ E A+ +I +L D LN ++ + V +LS K I + E + + + +T + + +S + VS A + LCE +AS+P +P +R+ + R+VA+++ +LL + +++ + G +K+ TD
Sbjct: 10 PMTGDSRRLALRIHVPDADVTKTLVFDALMTVGQACDQIRQQIREIDGLDNPKDYGLFLPHEDSKKGLWLDHSRSLEHYILRNGDTVEYKYRYRWLYIRTMDGTRKTLRVDDSKTLSELMLPICTKMGIYNYEEYLLVRDVDEAEK--DRTMTLRKSHQTGMSGTLRDAEKMDKLRRELHTDDDVTWLNPSQSLRQQGIGEKEILLLRRRYFFSDMNVDARDPVQLNLLYVQLKDAILNGTHPVTLDEAVYLAAIQCQVELGNYNPEKFKSGFLDLKDFLPKEFLK-VKGLEKKIFQQHATLNGISDVEARVKYCHFCRSLKTYGITFFLVKEKMKGKNRLIPRLLGITRDSVVRLDERTKEVVKVWPLTSILKWAASPNAFTMDFGEYSPDEYYTAQTSEGEQISQLIAGYIDIILKKQKARDHQGLQGDEESAMYEENVRAERAKIVQSA----RRSVGPAD---RDR----NAATDGVSETIDSQRVETQMNGYTGDQLNGYMGTTERHLITLESPVSIDGQSVVSRQRNDNQDDFMTGGTHTYHYQTMTP--VQRALMLTIDENMEVLEQGKQMLDIGSPSERVLLNIGHDEASKRWLDESMGASQVKVADDVGAMNAAVAQAVRSANRADAVLSQTAGYEVGAGSDPGDDLMMMQQSFRVVTVHFPAFVDDVKRVAVLRRETGALQAEAEENPETREYITMRAENSAQNLLGAARTVADSFSELLKAATPLATQQQTDYEISSTVQYSDHAVPVGGSSRKAILEAANRVGEASNDFLRFVIQDGEEQAMATDDTGTGLRSFAEEERAYQDELLGLAKEVANATAGLVVKAKHLATQTNLDPEHQQDVVFAATQTGLCTSQLVACTKVLAPTIRQPTCQQQLSESAREVSVAVDGVVKAARGAGQSVYDQQQNLSPEESAEVNEAVRDVDDAATEVRNTLDRLNAHLLKESVRPYRGDNLDLFQAAYEALQR----ETDGQRMVAAARRLSQVSAQMIADVKTQA-EQADGDPERQTKLFAAAKQLADATTDLINHAKVCSTAPDSEPNQTKLKQSADELVVVAYAS-AAELLNARVMRSLQAAARAVVTASTHLVNTSRCAAKKSRANNYHILEDARVVNELTPKLVAAIRYVRSHPDDPLAQLELICACQQVVEPCSILARSSRSMAPTVSDPSLQSTLELSMSQMVVAVETLRACLGRAAPIARQLQMDGALARLLRLIRESEETESSARAGSLTALPDDKVEDRFQMLSLGVRDGIDAGNQIGAAVESLTSAYSVYPSASGRDQEE-----DWLGSSSNQLASALADLVQATRCIAAA-------DMATTKGVAGEVLTEFLHSCVLSTQIAYQLVCESRKLEVLEPSQTPETQAALLQRNTEVNTKCRDYITDLTAALTGCLRGLPGQREISEASIMVKRRRHDLVRFAEDPTIIEFHDADQISPADTRTDFTGAAVEFNQATVELTSCYTPNNFKRSSLRFAGAYDNLVDRGLRLSRSKPPEDITG--------KEIVNELVQISDKSEILLEDAQQVCNEPEIQPLRNRLHSAAKSVTDSINHLLNLSTSGLAPGATDCDAALRRLEALRPLLEQPTRPINQHIYHECIETVAQSTV-PLADGLRGISNAVNENNADKFSVHVQQTTDSICLLIEETAQAAYLIGIAHPKSKPGTKSPVDRALFEGIQREIQDACKAITSPQVTERQ----VVSLANDISSNLRTLCDACTSISAQATSAEERRQLKTLTQDMMQSITELV----KRSADWSEEGKRATANNAHLVNTHVSQLVRFVTCGPQFAGHPARITAEARESQQPLCTAGISCLDAGKSVLIASKHMVNSAQTKNESADSSFMNFSAASHDLSDGIKHLVSVLKSHAPGQAECQQALENIARLLRDLQRDEMAIMD--DRFPQRHDNTAEGFQKQLTTSVRAVMEMAPTLGRAATSEAERLGHSVRELDALLPGIVSSALGSASRAPPGCPSQLIYLGHTRTLLESSEQLVLAAKEAGGNPRSVHLHAPIEDAVRAQIESCEDLLSAVDSIVSQHDFMEKLMAVLNQSQSVVDQPARVPRDAHFTDYQARMLRLARHMEQQTQSAVIVSRRADATAE---LPPVANNLAQDYAELCLVCRDASETLPDGRQSDQLRSAVKNVGNATRALIQSATSGAFARTRDGPGRQLVEESSSQRNLDYAAGLMNDRLRELIALLEAQGPGTQACLQGASTVSGIIADLDTTILFASSGTLHPPIHDDFDVANLDRRRAGERFSLTIRGADDFGHEAQDNFISIRESINRAADALVEDTRSLVSGAGEDQNRLAGSTHLAVRNISQLAEVVKQGASILGPGQLDNQVALLEGAKETAVSVRTLFLTASQLHGRQKPDPVYEDLRLSGDAVQNSAAKLVTLANSIDSESTRGTKALIAA--TKFCHQMADHVSTMGAELSASQVEMNSAVNQCGSASTLLSTTSLVSRYMAPEELSRAVAGPMQLVVSKAVLASSSR------KQDDGLTAANTARHALIDLVQACKGLVRQQEVSKEARQSTKSAVKQIASEFAKLLDGVKCVIHADNEKDRERISLAAGRIAALSSQLLNIAEGLKEGPRLVMYFRASSPEWRDVAEKFLGRHVAFHHHYVPCYGKDGSSVTSTRVASHQTSCLQMRLDSVGRVVVGEGASSEAEKRIDAALQRLED-GLNRART-HEQATTPSVQPILSMTKSIALAAREFIQAVR-TSSGAGETPKTSRSGSETATLGRSELSVSVATEYLCELARFCSASRPEGPTAAPVDDPVKIMPSRERLLAAIRQVASTSAELLYAARSRRQLPPTRLSAVQATGKAVKEQTD 2801
BLAST of Talin-1 vs. Ensembl Cavefish
Match: tln1 (talin 1 [Source:ZFIN;Acc:ZDB-GENE-031002-48]) HSP 1 Score: 936.021 bits (2418), Expect = 0.000e+0 Identity = 693/2278 (30.42%), Postives = 1172/2278 (51.45%), Query Frame = 1
Query: 55 LRIHIVDADVTKIVPLDPEATIFQLCETIRKNIREAQTKSPKSYGLYLPHDDLKKGLWLDNSKTLQHYILKRGDTIEYRNRSRWLHIRTMDGTNKTLKVDDSWTVSELMLTVCTKLGIYNYDEYSLISDKMDFSPGIDKTLSMKRGISINXXXXXXXXXXXXYHTEDGLNWLNPSQSLRQQGIEESEVLLLKRKYFFSDMNVDSRDPIQLSLLYEQLKDAVINGTHPVTLPEAIELAGLQCQVQLGNYSADKFKPGFLDLRECLPKEYQKNPKTVEKKIFNQHSKSKDLSEVEAKEKYCLLCRSFKTYGITFFLVKEKVIGKNKLIPRLLGVNKESVVQVDEKTKEIINTWPLTSIRKWAASFNGFTMDFGEYSPDEYYTAQTDKGERISQLIAGYIDIILKRKKAKDHLGVDADEESIMYEENIAPSKAIIVEH----VPKQKRSSVSEEDVVIRKKAHMANSSVRMNSQASDSVCSQDCTDFYQEDINMSRQTSSLGRTQSPSSSLTTNSMHY-RMSDDDIRQKLYIISLQDNLDTIQKYKDQLMIENKGPEIGKDEASQQWIYVNIDNSRQRMADEIGAMNAAVAQVLRSAQGLATIXXXXXXXXXXXXIAKMQNSFSLITVHLPSLMEEIRTAAYYQDQLTDEDVSGEELIAAAKRLADAFTNLIKAAYPVEDQKRSLNRKEIFDAANAVGEASSDLLQQITEQENCQIELKSERPYSIIMITEEDQLYQEELLRLAKSVANETTNLIKQVKVIAVEAENPSDQKKVVMAATETGLAISQLISTTKIVAPTIEQSVCQEQLIFSIEDVSKAIQVVVESSNKATQSEELQDLTVQAANQVQEALDTLMKHLRXXXXXXXXXXXXXXAYENI----QEXXXXXXXXXXXXXXXRRLAQATTAMISEIQLKAVNEQYKTPEERDKLINAAKQLAEATTVLIDSAKNCTMDKDEMNLRYTLREATERFIVVTYTTECATYIQEQVIDHLLVAARKAATTGTHLINTSLSAAK--KSRASNFKVCNDGRELSNQISNLIVAIKEARRDPKDHLAQLELIAACRDYIDPSEQLSQSNKYMWPTVSDPSLQTALNQSINQSVIATEELKKCVHQADLMCQHLDLSAALEQLKRLEQNLKSIKNSIERENLIPLPDEKSDESAALLIKSVRRSGSAANQFKNDLESRCVVYEQTNGEDSYQNLENLDVAGQKARELSMALDRLVHAARGVAASIEFENQESENNDKNLEKLAQLQIVNNCLEAVKAARDLVIEAK---SSPPDNDQMDRAQQASVRXXXXXXXXXXXXPGQRDLDMLSKHIESKKHQFAENRLPIQQNNNINLSNCRSELTDTTFDFNQAVNELVSAPSFNL--VNKGCKKMRMSYDRIVEICNVLVHDPFDESDSALHHLSSNRDHIANGVMIMSEDCQTLLDKVKKIQCEPDNIIVRKQLQEATKMLLDSINRLLTNISTNLRPGQKECDKTIYRLESMRPILDNPVHPISHKDYFECLDFIIDKTVQPLADSLKNIPAAVKDENNQKFIDSIYHCADSVCMLLEETAQTAYLVGVGDVRSKIGNKGLADHTSFLQIQKEISENCQTICNPDTTARQDSSLMISTAGQIAENSRKLCEASK--TIMISFPNDKIKLSDKTKITLLAVSELMTGVQNLNQNFNEDNRKEVESLSGKVQDNVAELVQLLLSYKFAGDAAIISEEAKESQGPIKAAGITVLDTAIEVIQCSKALISSEANEELFIAYSSSCKDLNDALKHLISTIKESAPGQKECDEXXXXXXXXXXQAYDSKMKIMKHRSRTISRTFESEESYQNILQSALIQMPHCINELSRAGKKEPEQLARIFSRQTQLLESMVNSCICAANQTDLIQNSNIYLEHLITILEASEQLLKAVKKSGGNPKANSVHSQIDEMAQGVIESCEDLLAALDKISFKQGNVNTIVETITKSSAKVQESAIIPEKSRFGNSQSKMLDICYDMNNLTTDISSNANSESTQRLLAPLTQNLTQRYDDLCRACQGAVATLSNENNGKQLQECVQTVGKVSISLVKSTTEVRPSVASSISN--LQAKTQELHKRIDDVIQLLISSNVGTQACTQAIKILKEINSDIDTSILFVKSADIQNDDREYYSVKELFKKSRNSVIDNSSELVRNIKLIVSKDVCDVNILQESADQIAITSQSLANDVKVGLEHLNSSTSQYNIELLVSFQEVIVSLISFLEVARNTSGLPYTDPLFQNLKEEGKCSINAITSLLKVLKSMDDVNLKDFQAIDNAI 6828
L + I +V K + +P ++ C IR+ + EAQ P YGL+L +D KKG+WL+ K L +Y+L+ GDT++Y+ + R L IR +DGT KT+ VDDS VS++++T+C ++GI NYDEYSL+ D + + T ++KR ++ +D +K++KLK+K HT+D LNWL+ ++LR+QG+EE+E+LLL+RK+F+SD NVDSRDP+QL+LLY Q +D ++NG+HPV+ +A E AG QCQ+Q G+++ K KPGFLDL+E LPKEY KN EKKIF H ++++E+EAK Y L RS KTYG++FFLVKEK+ GKNKL+PRLLG+ KESV++VDEKTKE++ W LT+I++WAAS FT+DFG+Y D YY+ QT +GE+I+QLIAGYIDIILK+KK+KDH G++ DEES M E++++P K+ +++ V K + SV+ VI + S +M S I ++Q +T+ MH M Q+ ++ ++ +Q + L + P +G D ASQ W +D S+ + ++ A+ A A ++ G + I+ S L +LME DE +G++L+ AA+ LA A ++++K A P + R + + AA VG+AS +LLQQI E ++ DQ +Q+ L++LAK+VAN L+ + K +A + E+ + Q +V+ AAT+ L+ SQL++ T++VAPTI VCQEQLI + + V+K+++ VE+S AT E L AA V +AL+ L++H+++ + A + I + + S D ++V AR LAQAT+ +++ I KA E E KL++AAK LA+AT ++++AK + D + LREA E + T I++++++ L AA++AA T I + AA K+ A+ ++ + +++QI L+ ++ ++ P AQL LI + ++++ P ++ + K PT+SD + L+Q A EL+ +A C L++ AL ++ LE++++ K + L PLP E ++ + L + + SA Q + E G ++Y L DVA + A + E+ ++ N A L + ++ K+A +L+ E K + P D D R Q + LS AL+ ++ LPGQRD+D + + + ++ P + + ++ L NQ+ NELV A + K K + +E D +S S ++ + + +S LL K + +P++ ++ QL A + + DSIN+L+T + T PGQKECD + LE++R +L+NP ++ YF+C+D +++ + + L +++ I K+ N +F D++ + ++C L E Q AYLVGV D S G KGL D F + ++ I CQ + +P T Q ++S A +A+++ LC A + + S P K + K + + L+ ++ L+ FN++NR++ ++ +G + + V L + +FA A IS E + PI AA T+L+++ +IQ +++L + + + + + ++D++K LI+ +++ APGQ+ECDEA+ +L I++ + + + + R S E+ + +++ ++ H I+ ++ A + + QL S+ E ++ + I A++ Q L+ T+ E++ Q+L K++GGNPKA ++E Q + E+ +DL L + + G V +V+TIT++ ++++ A+ PE S F + Q+ M+ A+A E G +++ V +G LV ++ S SI+ L +++ +++ V+ L + N GTQAC A + I +D+DT+I+F + + ++ E F R ++ + LV + KL+VS L ++A T LA+ VK+G L S + + L+ + ++V +L + + +G P+ DP LK K + +TSLLK +K+++D K +A++ I
Sbjct: 4 LSLKIGVGNVVKTMQFEPSTMVYDACRIIRERVPEAQLGQPNDYGLFLSDEDPKKGIWLEAGKALDYYMLRNGDTLDYKKKQRPLKIRMLDGTVKTVMVDDSKIVSDMLMTICARIGITNYDEYSLVRD-IGEEKKEETTGTLKRDKTLLRDDKKMEKLKQKLHTDDELNWLDHGRTLREQGVEETEMLLLRRKFFYSDQNVDSRDPVQLNLLYVQARDDILNGSHPVSFDKACEFAGYQCQIQFGDHNESKHKPGFLDLKEFLPKEYIKNKG--EKKIFQAHKNCQNMTEIEAKVSYVKLARSLKTYGVSFFLVKEKMKGKNKLVPRLLGITKESVMRVDEKTKEVMQEWSLTNIKRWAASPKSFTLDFGDYQ-DGYYSVQTTEGEQIAQLIAGYIDIILKKKKSKDHFGLEGDEESTMLEDSVSPKKSTVMQQQFNKVGKVETGSVAMP--VIMRSGAGGQGSFQMGS------------------IPQAKQ------------QITSGQMHTGHMPPLTSAQQALTGTINSSMQAVQAAQASLDDFDALPPLGTDAASQAWRKNKMDESKHEIHSQVDAITAGTASMVNLTAGDPAETDYTAVGCAVTTISSNLTEMSKGVKLLAALME-------------DEGGTGQQLLGAARNLACAVSDMLKTAQPASTEPR----QNLLQAAGNVGQASGELLQQIGE-------------------SDADQQFQDMLMKLAKAVANAAAALVLKAKNVAQKTEDSAQQNRVIAAATQCALSTSQLVACTRVVAPTISSPVCQEQLIEAGKLVAKSVEGCVEASQGATGDEHLLKQVGAAATGVTQALNELLQHIKQYASGGQPIGRHGEATDRILDVTENIFSSMGDAGEMVRQARILAQATSDLVNAI--KADAEGETDLENSRKLLSAAKLLADATARMVEAAKGAAANPDSEEQQQKLREAAEGLRMAT-NAAAQNAIKKRLVNKLENAAKQAAAAATQTIAAAQHAASSNKNPAAQQQLVQSCKVVADQIPQLVQGVRGSQAQPDSPSAQLALIGSSQNFLQPGAKMVTAAKATVPTISDQASAMQLSQCAKNLASALAELRTAAQKAQEACGPLEIDNALTVVRGLERDIQEAKAAAAEGKLRPLPGETLEKCSQDLGSNTKAVSSAVAQL---------LSEAAQGNENYTGLAARDVAQALRSLAAAA----------RGVAATTEDPQARN--------AMLDCTGDVMD--KSA-NLIEETKRAVAKPGDPDCQQRLAQVAKALSQALNRSVNCLPGQRDVDNAIRTVGEASKKLLSDQFPA---SGKSFQEAQAGLNQAAAGLNQSANELVQASRGTTQDLAKASGKFGKDFSHFLEAG----VDMAGQSQS-----KEDQTQVVTNLKTISMSSSKLLLAAKALSTDPNSPNLKNQLAAAARAVTDSINQLIT-MCTQQAPGQKECDNALRELETVRGMLENPTEAVNDLGYFDCIDSVMENS-KVLGEAMAGISHNAKNSNLPEFGDAVSSASKALCGLTEAATQGAYLVGVSDPNSHAGQKGLVDPAQFAKAKQSIQMACQNLVDPACTQSQ----VLSAATIVAKHTSALCNACRLASSKTSNPVAKRQFVQSAKEVANSTANLVKSIKALDGAFNQENRQKCKAATGPLIEAVDNLTAFASNPEFASVPAQISPEGLAAMEPIVAAAKTMLESSTGMIQTARSLAVNPKDPPKWSVLAGHSRTVSDSIKKLITNMRDKAPGQRECDEAIEVLNNCIREVDQASLAAISQ--QLTPRDDISHEALHEQMAASVQEISHLIDPVAIAARSDASQLGHKVSQMASYFEPLIMAAIGTASKILNSQQQMSVLDQTKTLAESALQILYTAKEAGGNPKAAHTQEALEEAVQMMKEAVDDLGGTLTEAAGAAGAVGGMVDTITQAINRMEDQAVEPEGS-FVDYQTTMVKTAK------------------------------------------AIAVTVQEMIGSHIKKQVTELGYSCTGLVTKAGALQCSPNDSITKKELIDSARKVSEKVSHVLAALQAGNRGTQACITAASAVAGIIADLDTTIMFATAGTLNREN------AETFADHREHILKTAKVLVEDTKLLVSGAGASQEKLAQAAQSSVNTITKLADVVKLGAASLGSEDPETQVVLINAVKDVAKALGDLIRATKAAAGKPHDDPAMLQLKNSAKVMVTNVTSLLKTVKAVEDEATKGTRALEATI 2107
BLAST of Talin-1 vs. Ensembl Cavefish
Match: tln2b (talin 2b [Source:ZFIN;Acc:ZDB-GENE-130325-1]) HSP 1 Score: 905.205 bits (2338), Expect = 0.000e+0 Identity = 680/2284 (29.77%), Postives = 1161/2284 (50.83%), Query Frame = 1
Query: 49 FELRIHIVDADVTKIVPLDPEATIFQLCETIRKNIREAQTKSPKSYGLYLPHDDLKKGLWLDNSKTLQHYILKRGDTIEYRNRSRWLHIRTMDGTNKTLKVDDSWTVSELMLTVCTKLGIYNYDEYSLISDKMDFSPGIDKTLSMKRGISINXXXXXXXXXXXXYHTEDGLNWLNPSQSLRQQGIEESEVLLLKRKYFFSDMNVDSRDPIQLSLLYEQLKDAVINGTHPVTLPEAIELAGLQCQVQLGNYSADKFKPGFLDLRECLPKEYQKNPKTVEKKIFNQHSKSKDLSEVEAKEKYCLLCRSFKTYGITFFLVKEKVIGKNKLIPRLLGVNKESVVQVDEKTKEIINTWPLTSIRKWAASFNGFTMDFGEYSPDEYYTAQTDKGERISQLIAGYIDIILKRKKAKDHLGVDADEESIMYEENIAPSKAIIVEH----VPKQKRSSVSEEDVVIRKKAHMANSSVRMNSQASDSVCSQDCTDFYQEDINMSRQTSSLGRTQSPSSSLTTNSMHY-RMSDDDIRQKLYIISLQDNLDTIQKYKDQLMIENKGPEIGKDEASQQWIYVNIDNSRQRMADEIGAMNAAVAQVLRSAQGLATIXXXXXXXXXXXXIAKMQNSFSLITVHLPSLMEEIRTAAYYQDQLTDEDVSGEELIAAAKRLADAFTNLIKAAYPVEDQKRSLNRKEIFDAANAVGEASSDLLQQITEQENCQIELKSERPYSIIMITEEDQLYQEELLRLAKSVANETTNLIKQVKVIAVEAENPSDQKKVVMAATETGLAISQLISTTKIVAPTIEQSVCQEQLIFSIEDVSKAIQVVVESSNKATQSEELQDLTVQAANQVQEALDTLMKHLRXXXXXXXXXXXXXXAYENI----QEXXXXXXXXXXXXXXXRRLAQATTAMISEIQLKAVNEQYKTPEERDKLINAAKQLAEATTVLIDSAKNCTMDKDEMNLRYTLREATERFIVVTYTTECATYIQEQVIDHL--LVAARKAATTGTHLINTSLSAAKKSRASNFKVCNDGRELSNQISNLIVAIKEARRDPKDHLAQLELIAACRDYIDPSEQLSQSNKYMWPTVSDPSLQTALNQSINQSVIATEELKKCVHQADLMCQHLDLSAALEQLKRLEQNLKSIKNSIERENLIPLPDEKSDESAALLIKSVRRSGSAANQFKNDLESRCVVYEQTNGEDSYQNLENLDVAGQKARELSMALDRLVHAARGVAASIEFENQESENNDKNLEKLAQLQIVNNCLEAVKAARDLVIEAKS---SPPDNDQMDRAQQASVRXXXXXXXXXXXXPGQRDLDMLSKHIESKKHQFAENRLPIQQNNNINLSNCRSELTDTTFDFNQAVNELVSAPSFNL-VNKGCKKMRMSYDRIVEICNVLVHDPFDESDSALHHLSSNRDHIA--NGVMIMSEDCQTLLDKVKKIQCEPDNIIVRKQLQEATKMLLDSINRLLTNISTNLRPGQKECDKTIYRLESMRPILDNPVHPISHKDYFECLDFIIDKTVQPLADSLKNIPAAVKDENNQKFIDSIYHCADSVCMLLEETAQTAYLVGVGDVRSKIGNKGLADHTSFLQIQKEISENCQTICNPDTTARQDSSLMISTAGQIAENSRKLCEASK--TIMISFPNDKIKLSDKTKITLLAVSELMTGVQNLNQNFNEDNRKEVESLSGKVQDNVAELVQLLLSYKFAGDAAIISEEAKESQGPIKAAGITVLDTAIEVIQCSKALISSEANEELFIAYSSSCKDLNDALKHLISTIKESAPGQKECDEXXXXXXXXXXQAYDSKMKIMKHRSRTISRTFESEESYQNILQSALIQMPHCINELSRAGKKEPEQLARIFSRQTQLLESM-VNSCICAANQTDLIQNSNIYLEHLITILEASEQLLKAVKKSGGNPKANSVHSQIDEMAQGVIESCEDLLAALDKISFKQGNVNTIVETITKSSAKVQESAIIPEKSRFGNSQSKMLDICYDMNNLTTDISSNANSESTQRLLAPLTQNLTQRYDDLCRACQGAVATLSNENNGKQLQECVQTVGKVSISLVKSTTEVRPSVASSISNLQ----AKTQELHKRIDDVIQLLISSNVGTQACTQAIKILKEINSDIDTSILFVKSADIQNDDREYYSVKELFKKSRNSVIDNSSELVRNIKLIVSKDVCDVNILQESADQIAITSQSLANDVKVGLEHLNSSTSQYNIELLVSFQEVIVSLISFLEVARNTSGLPYTDPLFQNLKEEGKCSINAITSLLKVLKSMDDVNLKDFQAIDNAI 6828
L+I + +V K + +P ++ C IR+ + EAQT YGL+L DD +KG+WL++ +TL +Y+L+ GD +EY+ + R I+ +DG KT+ VDDS TV EL++T+C+++GI NY+EYSLI ++ + D ++K+ ++ +D+ K++KLK K HT+D LNWL+ S++ R+QG+EESE LLL+RK+F+SD NVDSRDP+QL+LLY Q +D ++NG+HPV+ +A E AG+Q Q+Q G + K KPGFLDL+E LPKEY K + EK+IF H +++E+EAK KY L RS +TYG++FFLVKEK+ KNKL+PRLLG+ KESV++VDE+TK+++ WPLT++++WAAS FT+DFGEY + YY+ QT +GE+ISQLIAGYIDIILK+K++KD G+D DEES M EE+++P K+ I++ V + + SV+ ++ S S+ D + NM G +P +TT MH M + Q+ + ++ ++ +Q+ + L + P +G+D AS+ W+ +D S+ + ++ A+ A A V+ G T + I+ S L +LME DE SG+ L+ AA+ L A ++L++A P + R + + AA ++G+AS DLL+Q+ E E D+ +Q+ ++ LAK+VAN L+ + K +A AE+ Q +V+ AAT+ L+ SQL++ TK+V+PTI VCQEQL+ + V ++++ V++ + A++ EL AA V +AL L++H+R + + + A + I + + S D ++V AR LAQAT+ +++ ++ A E + KL+ AAK LA+AT ++++AK + + + LREA E V T I++++++ L AA T T + +A+ K+ AS+ ++ + + +++ I L+ ++ ++ P+D AQL LI A + ++ P ++ S+K PTV+D + L+Q EL+ +A C L++ +AL ++ L+ L+ K + L PLP + ++ A L + + GS+ Q C G + Y G ARE + AL L AARGVAA E+ + ++++ ++ + L+ EA SP D + R Q + +S +L+ C++ LPGQ+D+DM + I +A + L +Q L C + + N+ V S L V G K +D D H S D I + +S LL K + +P + L A + + +SIN+L+T + T PGQKECD + LE++R +LDNP P+S YF+C++ +++ + + L +S+ I K + F + + + ++C L E Q +YLVGV D S+ G++GL D F + + I CQ++ +P ++ Q ++S A +A+++ LC A + + + P + K + L+ ++ L+ +F+++NR+ + + + V L + +FA A IS E +Q PI + ++LD++ ++++ +++L+ + + + + + ++D++K LI+ I++ APGQ+ECD ++ + K I+ + + + R S E+ Q + SA+ ++ H I +S A + E QL ++ + E + V S A+ D Q NI L+ T+ E+S Q+L A K+ GGNPKA+ H I E AQ + E+ +D++ L++ + + G V +VE+I ++ ++ E F + Q+ M+ A+A + E G Q++ VQ +G I LV+ ++ S S + + A+T + +++ V+ L + N GTQAC A + I +D+DT+I+F + + ++ E F R +++ + LV + KL+V+ L ++A A T L + VK+G + S + + L+ + ++V +L + + +G DP LK K + +TSLLK +K+++D + +A++ I
Sbjct: 4 LSLKICVRQCNVVKTMQFEPSTPVYDACRIIRERVPEAQTGQASDYGLFLSDDDPRKGIWLESGRTLDYYMLRNGDILEYKKKQRPQKIKMLDGAIKTIMVDDSKTVGELLVTICSRIGITNYEEYSLIQEQGEERKE-DGMGTLKKERTLLRDERKMEKLKAKLHTDDDLNWLDHSRTFREQGVEESETLLLRRKFFYSDQNVDSRDPVQLNLLYVQARDDILNGSHPVSFDKACEFAGIQAQIQFGPHVEHKHKPGFLDLKEFLPKEYIKQ-RGAEKRIFQDHKSCGEMTEIEAKVKYVKLARSLRTYGVSFFLVKEKMKSKNKLVPRLLGITKESVMRVDERTKDVVQEWPLTTVKRWAASPKSFTLDFGEYQ-ESYYSVQTTEGEQISQLIAGYIDIILKKKQSKDRFGLDGDEESTMLEESVSPKKSTILQQQFNRVGRVEHGSVALPGIM-----------------RSGSIGGPD-------NFNM-------GSMPAPQQQITTGQMHRGHMPPLSLAQQALMGTINSSMQAVQQAQADLGEVDNLPPLGQDRASRVWVQNKVDESKHEIHSQVDAITAGTASVVNLTAGDPTDTDYTAVGCAITTISSNLTEMSKGVKLLAALME-------------DEVGSGQNLMCAARTLTGAVSDLLRAVEPASGEPR----QTVLTAAGSIGQASGDLLRQMGEGET-------------------DERFQDIMMNLAKAVANAAAMLVLKAKNVAQVAEDTVLQNRVITAATQCALSTSQLVACTKVVSPTISSPVCQEQLVEAGRLVERSVEGCVKACHAASEEAELLRQVNGAAGAVSQALSDLLQHVRHYASCGEPIGRYDQATDTIMTVTESIFTSMGDAGEMVRQARVLAQATSDLVNAMRSDA--EAEVDVDNSKKLLAAAKLLADATARMVEAAKGAAAHPENEDQQQRLREAAEGLRVAT-NAAAQNAIKKKLVNRLEIAAKQAAAAATQTIAAAQNAAASNKNTASHQQLVHSCKAVADHIPQLVQGMRSSQAQPEDLSAQLTLIIASQSFLQPGSKMVTSSKSAIPTVTDQAAAMQLSQCAKNLATCLAELRTAAQKAHEACGPLEIDSALNAVQTLKNELQDAKMAAFDGQLKPLPGDSLEKCAQDLGSTSKAVGSSMAQLLT-----CAA----QGNEHY--------TGVAARETAQALRTLAQAARGVAAC-------------TAERQSAAAMLDSASHVMEGSAMLIHEAHQALISPGDAESQQRLAQVAKAVSHSLNNCVNCLPGQKDVDMALRSI---GEFYANSYLCVQ------LPPCSKSFQEAQTELNRTVVHSSRGTSSQLAVASG--KFSQDFDEF-----------LDAGIEMAGHTQSKDDQIQVIGNLKNISMASSKLLLAAKSLSVDPGAANAKNLLAAAARAVTESINQLIT-LCTQQAPGQKECDNALRELEAVRGMLDNPNEPVSDLSYFDCIESVMENS-KVLGESMAGISQHCKTGDVPAFGECVGVASKALCGLTEAAGQASYLVGVSDPNSQSGHQGLVDPIQFAKANQAIQMACQSLVDPASSPSQ----VLSAATIVAKHTSALCNACRLASSKTANPVARRHFVQSAKEVANTTANLVKTIKALDGDFSDENRERCRVATTPLIEAVENLSTFASNPEFASIPAQISNEGSAAQEPILRSARSMLDSSTQLLETARSLVINPKDPPTWSILAGHSRTVSDSIKSLITAIRDKAPGQRECDHSIDSINKCIRDIEQASLAAVGQ--SLPCRDDISLEAVQEQVTSAVQEIGHLIEPISTAARGEAAQLGHKVTQLSNYFEPLIVASVGLASKHMDHQQQMNI-LDQTKTLAESSLQMLYAAKEGGGNPKASHTHDAIAEAAQLMKEAVDDIMVTLNEAASEGGMVGGMVESIAEAMGRMDEGTPPEPDGTFVDYQTTMVKFSK------------------------------------------AIAITAQEMVGLQIKTRVQELGHGCIYLVQKAGALQMSPTDSFTKRELIECART--VTEKVSMVLSALQAGNKGTQACITAASSVSGIIADLDTTIMFASAGTLNAENEES------FADHRENILKTAKALVEDTKLLVAGAASSQEKLAQAAQSSAKTITQLTDVVKLGAASMGSEDPETQVVLINAVRDVAKALAELIGATKCAAGKAADDPSMYQLKSAAKVMVTNVTSLLKTVKAVEDEATRGTRALEATI 2103
BLAST of Talin-1 vs. Ensembl Cavefish
Match: tln2a (talin-2-like [Source:NCBI gene;Acc:103042966]) HSP 1 Score: 889.797 bits (2298), Expect = 0.000e+0 Identity = 678/2291 (29.59%), Postives = 1165/2291 (50.85%), Query Frame = 1
Query: 49 FELRIHIVDADVTKIVPLDPEATIFQLCETIRKNIREAQTKSPKSYGLYLPHDDLKKGLWLDNSKTLQHYILKRGDTIEYRNRSRWLHIRTMDGTNKTLKVDDSWTVSELMLTVCTKLGIYNYDEYSLISDKMDFSPGIDKTLS-MKRGISINXXXXXXXXXXXXYHTEDGLNWLNPSQSLRQQGIEESEVLLLKRKYFFSDMNVDSRDPIQLSLLYEQLKDAVINGTHPVTLPEAIELAGLQCQVQLGNYSADKFKPGFLDLRECLPKEYQKNPKTVEKKIFNQHSKSKDLSEVEAKEKYCLLCRSFKTYGITFFLVKEKVIGKNKLIPRLLGVNKESVVQVDEKTKEIINTWPLTSIRKWAASFNGFTMDFGEYSPDEYYTAQTDKGERISQLIAGYIDIILKRKKAKDHLGVDADEESIMYEENIAPSKAIIVEHVPKQKRSSVSEEDVVIRKKAHMANSSVRMNSQASDSVCSQDCTDFYQEDINMSRQTSSLGRTQSPSSSLTTNSMHY-RMSDDDIRQKLYIISLQDNLDTIQKYKDQLMIENKGPEIGKDEASQQWIYVNIDNSRQRMADEIGAMNAAVAQVLRSAQGLATIXXXXXXXXXXXXIAKMQNSFSLITVHLPSLMEEIRTAAYYQDQLTDEDVSGEELIAAAKRLADAFTNLIKAAYPVEDQKRSLNRKEIFDAANAVGEASSDLLQQITEQENCQIELKSERPYSIIMITEEDQLYQEELLRLAKSVANETTNLIKQVKVIAVEAENPSDQKKVVMAATETGLAISQLISTTKIVAPTIEQSVCQEQLIFSIEDVSKAIQVVVESSNKATQSEELQDLTVQAANQVQEALDTLMKHLRXXXXXXXXXXXXXXAYENI----QEXXXXXXXXXXXXXXXRRLAQATTAMISEIQLKAVNEQYKTPEERDKLINAAKQLAEATTVLIDSAKNCTMDKDEMNLRYTLREATERFIVVTYTTECATYIQEQVIDHLLV--AARKAATTGTHLINTSLSAAKKSRASNFKVCNDGRELSNQISNLIVAIKEARRDPKDHLAQLELIAACRDYIDPSEQLSQSNKYMWPTVSDPSLQTALNQSINQSVIATEELKKCVHQADLMCQHLDLSAALEQLKRLEQNLKSIKNSIERENLIPLPDEKSDESAALLIKSVRRSGSAANQFKNDLESRCVVYEQTNGEDSYQNLENLDVAGQKARELSMALDRLVHAARGVAASIEFENQESENNDKNLEKLAQLQIVNNCLEAVKAARDLVIEAK---SSPPDNDQMDRAQQASVRXXXXXXXXXXXXPGQRDLDMLSKHI-ESKKHQFAENRLPIQQNNNINLSNCRSELTDTTFDFNQAVNELVSAPSFNLVNKGCKKMRMSYDRIVEICNVLVHDPFDES-DSALH---HLSSNRD--HIANGVMIMSEDCQTLLDKVKKIQCEPDNIIVRKQLQEATKMLLDSINRLLTNISTNLRPGQKECDKTIYRLESMRPILDNPVHPISHKDYFECLDFIIDKTVQPLADSLKNIPAAVKDENNQKFIDSIYHCADSVCMLLEETAQTAYLVGVGDVRSKIGNKGLADHTSFLQIQKEISENCQTICNPDTTARQDSSLMISTAGQIAENSRKLCEASK--TIMISFPNDKIKLSDKTKITLLAVSELMTGVQNLNQNFNEDNRKEVESLSGKVQDNVAELVQLLLSYKFAGDAAIISEEAKESQGPIKAAGITVLDTAIEVIQCSKALISSEANEELFIAYSSSCKDLNDALKHLISTIKESAPGQKECDEXXXXXXXXXXQAYDSKMKIMKHRSRTI---------SRTFESEESYQNILQSALIQMPHCINELSRAGKKEPEQLARIFSRQTQLLESMVNSCICAANQTDLIQNSNIYLEHLITILEASEQLLKAVKKSGGNPKANSVHSQIDEMAQGVIESCEDLLAALDKISFKQGNVNTIVETITKSSAKVQESAIIPEKSRFGNSQSKMLDICYDMNNLTTDISSNANSESTQRLLAPLTQNLTQRYDDLCRACQGAVATLSNENNGKQLQECVQTVGKVSISLVK--STTEVRPSVASSISNLQAKTQELHKRIDDVIQLLISSNVGTQACTQAIKILKEINSDIDTSILFVKSADIQNDDREYYSVKELFKKSRNSVIDNSSELVRNIKLIVSKDVCDVNILQESADQIAITSQSLANDVKVGLEHLNSSTSQYNIELLVSFQEVIVSLISFLEVARNTSGLPYTDPLFQNLKEEGKCSINAITSLLKVLKSMDDVNLKDFQAIDNAI 6828
L+I + +V K + P ++ C IR+ + EAQT +GL+L +D +KG+WL++ +TL +Y+L+ GD +EYR + R ++ +DG KT+ VDDS TV EL+LT+C+++GI NYDEYS++ + + D+ +S +++ ++ +D+ K++KLK K HT+D LNWL+ ++ R+QG+EESE LLL+RK+F+SD NVDSRDP+QL+LLY Q +D ++NG+HPV+ +A E G+Q Q+Q G + K + G LDL+E LPKEY K + EKKIF +H +++E+EAK KY L RS KTYG++FFLVKEK+ KNKL+PRLLGV KESV++VDEKTKE++ WPLT++++WAAS FT+DFGEY + YY+ QT +GE+ISQLIAGYIDIILK+KK+KD G++ DEE+ M E++++P K+ I++ +Q S+ E + + SSV +T ++G SP +TT MH M Q+ + ++ ++ T+Q+ + L + P +G D AS+ WI +D S+ + ++GA+ A A V+ G E + + + I+ +L + + ++ A + DE SG++L+ AA+ L A ++L+ A P + R+ + +AA ++G+AS DLL+QI E+E D+ +Q+ L+ LAK+VAN ++ + K +A +E+ Q +V+ AAT+ L+ SQL++ K+V+PTI VCQEQL+ + + V +++Q V + AT EL AA V +AL L+ H+R + + + A + I + + S D ++V AR LAQAT+ ++ ++ A E + KL+ AAK LA+AT ++++AK + + + LREA E V T + I++++I L V AA T + +A+ K+ A++ ++ + +++ I L+ ++ ++ P+D A L LI A ++++ P ++ S K PTV+D + L+Q + EL+ H A C +++ +AL ++ L L+ + + + L PLP E ++ L + + GS+ Q C G + Y G ARE + AL L AA + A + ++++ E ++ + L+ +AK +P D + Q + +S +L+ C++ LPGQ+D+D+ K I E+ K E P + + +S+L T NQ+ ++V A R + ++ + D FDE D+ + H D + + +S LL K + P + L A + + DSIN+L+T + T PGQ+ECD + LE++ +LDNP P++ YF+C++ +++ + + L +S+ I K + F + + + ++C L E QT+YLVGV D S+ G +GL D F + + I CQ + +P ++ Q ++S A +A+++ LC A + + + P K K + + L+ ++ L+ +F+ +NR + + + + V L + S +F A IS E +Q PI + ++LD++I+++ +++L+ + + L+ ++ ++D++K LI+ +++ APGQ+ECD A DS K ++ + +R S E+ Q L S++ ++ H I+ +S A K E QL S+ E + + + A++ Q L+ T+ E++ Q+L A K+ GGNPK H I E AQ + E+ +DL+ L++ + + G V +V++I ++ K+ + F + Q+ M+ + D+ S S+ L L +T Y L + A AT E G Q++ VQ +G ++LV+ ++ PS + + L + + +++ V+ L + N GTQAC A + I +D+DT+I+F SA N + + S F + R +++ + LV + K +VS L +A A T L VK+G + + + L+ + ++V +L + + +G DP LK K + +TSLLK +K+++D + +A++ AI
Sbjct: 4 LSLKICVRQCNVVKTMQFKPATAVYDACRVIRERVPEAQTGPASEFGLFLSDEDPRKGIWLESGRTLDYYMLRNGDVLEYRRKQRPQKVKMLDGAVKTVMVDDSKTVGELLLTICSRIGITNYDEYSVVRETGEERR--DEGMSTLRKDRTLLRDERKMEKLKAKLHTDDELNWLDHGRTFREQGVEESETLLLRRKFFYSDQNVDSRDPVQLNLLYVQARDDILNGSHPVSFDKACEFGGIQTQIQFGPHIEQKHRTGLLDLKEFLPKEYVKQ-RGAEKKIFQEHKACGEMTEIEAKVKYVKLARSLKTYGVSFFLVKEKMKSKNKLVPRLLGVTKESVMRVDEKTKEVLQEWPLTTVKRWAASPKSFTLDFGEYQ-ESYYSVQTTEGEQISQLIAGYIDIILKKKKSKDRFGLEGDEEATMLEDSVSPKKSTILQ---QQYNSAGRVEHGSVALPGVLRTSSV-------------------------GPETLNVGTMPSPQQQITTGQMHLGHMPPLSAAQQALVGTINTSMQTVQQVQADLEEVEELPPLGDDLASKVWIQNKVDESKHEIHSQVGAITAGTASVVNLTAG----------GPEETDYTAVGCAITTISSNLSEMSKGVKLLAAL---VEDEVGSGQDLMRAARTLTGAVSDLLNAVEPTSGEP----RQTVLNAAGSIGQASGDLLRQIGEKET-------------------DERFQDVLMNLAKAVANAAAMMVLKAKNVAQVSEDTVLQNRVIAAATQCALSTSQLVACAKVVSPTISSPVCQEQLMEAGKLVDRSVQGCVNACLSATDDGELLKAVSAAAGVVTQALADLLAHVRNYDSCGEPIGRYDQATDTIMNVTENIFSSMGDAGEMVRQARVLAQATSDLVGAMRSDA--EAEIDVDNSKKLLAAAKLLADATARMVEAAKGAAAFPENEDQQQKLREAAEGLRVAT-SAAAQNAIKKKLITRLEVRAKQAAAAATQAIAAAQNAAASNKNTAAHQQLVQSCKAVADHIPQLVQGVRGSQGQPEDDSAHLALIIASQNFLQPGSKMVASAKSSVPTVTDQAAAMQLSQCAKNLSTSLAELRTAAHMAHEACGPMEIDSALTAVQTLRNELQDARTAAVKHQLKPLPGESLEKCGQDLGSTSKAVGSSMAQLLT-----CAA----QGNEHY--------TGVAARETAQALKSLGQAA-------------RGVAAATADAEAAVLMLDSAREVMQGSEMLISKAKEALETPGDTESQQTLAQMARSVSHSLNSCVNCLPGQKDVDLALKSIGEASKKLLMETLPPCSK----SFQEAQSDLNQTAAGLNQSAGDVVHAS------------RGTSSQLADASGKFSED-FDEFLDAGIEMAGHTQRKDDQLQVIGNLKNISMSSSKLLLAAKSLSVNPRAANAKSLLATAARSVTDSINQLIT-MCTQHSPGQRECDNALRELEAVIVLLDNPNEPVNGLSYFDCIESVMENS-KVLGESMAGISQNCKTGDVPAFGECVGVASKALCGLTEVARQTSYLVGVSDPNSQAGQQGLVDPIQFARANQAIQMACQNLADPGSSPSQ----VLSAATIVAKHTSALCNACRLASAKTTNPVAKRHFVQSAKEVANSTAILVKTIKALDGDFSAENRDKCRVATAPLIEAVDSLTVFVSSPEFGSVPAQISREGSAAQEPILQSARSMLDSSIKLLTTARSLVLNPKDPALWSLLAAHSHTVSDSIKSLITAVRDKAPGQRECDS-----------AIDSVRKCIREMEQACLSAVSQNLPTRQDISLEALQEQLMSSVQEVGHLIDPISTAAKGEASQLGHTVSQLASYFEPLSRAAVGVASKMMHHQEQMNLLDQSRTLAESALQMLYAAKEGGGNPKVTLTHDAIAEAAQLMREAVDDLMLTLNEAASEVGIVGGMVDSIAEAMGKLGAGTPSETEGSFVDYQTVMVKFSRAIAVTAHDMI--GKSVSSPEELGSLASQVTADYGQLALHGRLAAATAEPEEVGVQIKSRVQELGHGCMALVQKAGALQICPSDSITKRELMECARTVTEKVSLVLSALQAGNKGTQACITAASAVSGIIADLDTTIMFA-SAGTLNTENDSDS----FAEHRENILKTAKALVEDTKNLVSGAATSPEKLARAAQSSAKTITQLTEVVKLGAASIGPDDPETQVVLINAVKDVAKALAELISATKGAAGKAAEDPSMLQLKGAAKVMVTNVTSLLKTVKAVEDEATRGTRALEAAI 2152
BLAST of Talin-1 vs. Ensembl Cavefish
Match: mast2 (microtubule associated serine/threonine kinase 2 [Source:ZFIN;Acc:ZDB-GENE-050309-150]) HSP 1 Score: 649.047 bits (1673), Expect = 0.000e+0 Identity = 311/555 (56.04%), Postives = 405/555 (72.97%), Query Frame = 1
Query: 9565 IKPRSQSLNPCRSPGAYEQDIFILNHVYKERFPKATIQMMERLSAMLEELENENTVSW-EPISRLVHTQIMKHVKDILNMTNLEAITSTYFFELTQNLEKLLKETRLKCPE-SLARVRPIVQHLLFIIARPARLLECIEFDPKEFYKLLEVAENNLR---NVQTDVPKYIISKLGLDKDPYDIGSEELNTSLELNGGSLEIXXXXXXXXXXXXXXXXXLNMSQESNNSLELSFSKSMTPKESDFEDIKLISNGAYGAVHLVREKKTKKRFAMKKIRKDNLLLRNQVEQIFAERDIMTFADSPFVVGLYCTFETRKYLCMIMEYVEGGDVATLIKSIGPLPDELARMYFAETVLALEYLHNFGIVHRDLKPDNLLITLEGHIKLTDFGLSKVGLMNLTTTLLESVLNKDCTMFQDKQVFGTPDYIAPEVILRQGYDKMIDWWAMGIILYEFIVGCTPFYGDSTEELFGNIISGEIEWPQDPDPCVPDNAVNLITELLKRDPLVRLGAEGTHEVKEHEFFSDVDWQGLLRQKALFIPVLDHEDDTSYFDPRTSRYQH 11214
++PRS+SL+P RSP +++ +I ++NHVYKERFPKAT QM ERL+ + E + + + +H Q+++ +D L+ + ITS YF+EL +NLEKLL++ + + V +V+ L+ IIARPARLLEC+EFDP+EFY LLE AE + + +++D+P+YIIS+LGL +DP EE+ + G+ E + E+ +S E K+ TP+E DFE IKLISNGAYGAV LVR K+T++RFAMKKI K NL+LRNQ++Q F ERDI+TFA++PFVV ++C+FETR++LCM+MEYVEGGD ATL+K IG LP ++ARMYFAETVLALEYLHN+GIVHRDLKPDNLLIT GHIKLTDFGLSK+GLM+LTT L E + KD F DKQV GTP+YIAPEVILRQGY K +DWWAMG+ILYEF+VGC PF+GD+ EELFG +IS EI WP++ D +P +A +LI++LL+++PL RLG EVK+H FF+D+DW LLRQKA FIP L+ EDDTSYFD R+ RY H
Sbjct: 212 MRPRSRSLSPGRSPISFDHEIVMMNHVYKERFPKATAQMEERLAEFMSSSAPEKVMPLADGVLSFIHHQVIELSRDCLDKSREGLITSRYFYELQENLEKLLQDAHERSESVEVTFVTQLVKKLMIIIARPARLLECLEFDPEEFYHLLEAAEGHAKEGQGIKSDIPRYIISQLGLTRDPL----EEMAQLSSYDSGNPE---------------------TPETEDSSEPQ-PKTKTPREEDFETIKLISNGAYGAVFLVRHKETRQRFAMKKINKQNLILRNQIQQAFVERDILTFAENPFVVSMFCSFETRRHLCMVMEYVEGGDCATLLKHIGALPVDMARMYFAETVLALEYLHNYGIVHRDLKPDNLLITSMGHIKLTDFGLSKIGLMSLTTNLYEGHIEKDAREFLDKQVCGTPEYIAPEVILRQGYGKPVDWWAMGVILYEFLVGCAPFFGDTPEELFGQVISDEIIWPEE-DEALPPDAQDLISKLLRQNPLERLGTGSAFEVKQHRFFTDLDWNSLLRQKAEFIPQLESEDDTSYFDTRSDRYHH 739 HSP 2 Score: 117.472 bits (293), Expect = 2.966e-25 Identity = 56/126 (44.44%), Postives = 82/126 (65.08%), Query Frame = 1
Query: 12124 PAIVIHRRSRNFGFVIRAIRVFYGESNVYTLHHLIVGVDPEGSAFQAGLREGDLITHINGVSIVGAYHTEVVSMIIQSGASISLRVIPINKSFIRTDGPWRPA---GKMATKHHPRKAQHLRAGKK 12492
PAIVIHR + +GF +RAIRV+ G++++YT+HH++ V+ G A +AGLREGDLITH+NG + G HTEVV +I++SG +S+ P + I+ GP R KMA ++ K + + KK
Sbjct: 1009 PAIVIHRAGKKYGFTLRAIRVYMGDTDIYTVHHMVWHVEEGGPAHEAGLREGDLITHVNGEPVHGLVHTEVVELILKSGTKVSISATPFENTSIKV-GPARKTSSKSKMARRNKKTKTKEGQDSKK 1133
BLAST of Talin-1 vs. Ensembl Cavefish
Match: mast3b (microtubule associated serine/threonine kinase 3b [Source:ZFIN;Acc:ZDB-GENE-111209-1]) HSP 1 Score: 620.542 bits (1599), Expect = 0.000e+0 Identity = 301/561 (53.65%), Postives = 402/561 (71.66%), Query Frame = 1
Query: 9565 IKPRSQSLNPCRSPGAYEQDIFILNHVYKERFPKATIQMMERLSAMLEELENENTVSW-EPISRLVHTQIMKHVKDILNMTNLEAITSTYFFELTQNLEKLLKETRLKC-PESLARVRPIVQHLLFIIARPARLLECIEFDPKEFYKLLEVAENNLR---NVQTDVPKYIISKLGLDKDPYDIGSEELNTSLELNGGSLEIXXXXXXXXXXXXXXXXXLNMSQESNNSLELSFSKSM------TPKESDFEDIKLISNGAYGAVHLVREKKTKKRFAMKKIRKDNLLLRNQVEQIFAERDIMTFADSPFVVGLYCTFETRKYLCMIMEYVEGGDVATLIKSIGPLPDELARMYFAETVLALEYLHNFGIVHRDLKPDNLLITLEGHIKLTDFGLSKVGLMNLTTTLLESVLNKDCTMFQDKQVFGTPDYIAPEVILRQGYDKMIDWWAMGIILYEFIVGCTPFYGDSTEELFGNIISGEIEWPQDPDPCVPDNAVNLITELLKRDPLVRLGAEGTHEVKEHEFFSDVDWQGLLRQKALFIPVLDHEDDTSYFDPRTSRYQH 11214
I+PRS+SL+P R+ G+++ + ++NHVYKERFPKAT QM +RL ++ + ++T+ + + + Q+++ V+D L+ ++ +TS YF EL + LEKLL E + E + + +V+ +L II+RPARLLEC+EFDP+EFY LLE AE + + ++TD+P+YII++LGL++DP D S+ + + ++ LS +KS+ P ESDFE IKLISNGAYGAV+LVR K T++RFAMKKI + NL+LRNQ++Q+F ERDI+TFA++PFVV ++C+FETR++LCM+MEYVEGGD A L+K++GPLP ++AR+YFAETVLALEYLH++GIVHRDLKPDNLLIT GHIKLTDFGLSK+GLMN+TT L E + KD F DKQV GTP+YIAPEVILRQGY K +DWWAMGIILYEF+VGC PF+GD+ EELFG ++S +I WP D D +P +A ++IT LL + PL RLG G EVK+H FF+ +DW LLRQKA FIP L+ EDDTSYFD R+ RY H
Sbjct: 167 IRPRSRSLSPGRTSGSFDNETVMMNHVYKERFPKATAQMEDRLLDIVRQCSPDSTLPLGDGVLGFIQHQLVELVRDCLDKSHKGLVTSLYFLELQEKLEKLLHEALERSESEEVTIITQLVKKILIIISRPARLLECLEFDPEEFYHLLEAAEGHAKVGQGIKTDIPRYIINQLGLNRDPLDEVSQ----------------------------------LEEHYDSGPSLSPNKSVLTPPRRKPLESDFETIKLISNGAYGAVYLVRHKDTRQRFAMKKINRQNLILRNQIQQVFVERDILTFAENPFVVSMFCSFETRRHLCMVMEYVEGGDCANLLKNMGPLPVDMARLYFAETVLALEYLHSYGIVHRDLKPDNLLITSMGHIKLTDFGLSKIGLMNMTTNLYEGHIEKDTREFIDKQVCGTPEYIAPEVILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVVSDDIIWP-DGDDALPVDAQDMITRLLWQSPLERLGTGGATEVKQHTFFTRLDWNSLLRQKAEFIPQLEGEDDTSYFDTRSDRYHH 692 HSP 2 Score: 99.7525 bits (247), Expect = 5.944e-20 Identity = 45/112 (40.18%), Postives = 72/112 (64.29%), Query Frame = 1
Query: 12124 PAIVIHRRSRNFGFVIRAIRVFYGESNVYTLHHLIVGVDPEGSAFQAGLREGDLITHINGVSIVGAYHTEVVSMIIQSGASISLRVIPINKSFIRTDGPWRPA---GKMATK 12450
P I IH + +GF ++ IRV+ G S++YT+HH++ V+ A +AGLR GDLITH+NG S+ G HTE++ ++++SG ++L+ + + I+ GP R GKMA +
Sbjct: 931 PPIFIHSSGKKYGFTLQTIRVYMGNSDIYTIHHMVSSVEEGSPAHEAGLRAGDLITHVNGESVQGLVHTEMMELLLKSGNKVALQTTALEDTTIKV-GPARKTSCKGKMARR 1041
BLAST of Talin-1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000003776.1 (pep scaffold:Pmarinus_7.0:GL481036:4073:28398:-1 gene:ENSPMAG00000003436.1 transcript:ENSPMAT00000003776.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 695.271 bits (1793), Expect = 0.000e+0 Identity = 492/1602 (30.71%), Postives = 827/1602 (51.62%), Query Frame = 1
Query: 49 FELRIHIVDADVTKIVPLDPEATIFQLCETIRKNIREAQTKSPKSYGLYL---PHDDLKKGLWLDNSKTLQHYILKRGDTIEYRNRSRWLHIRTMDGTNKTLKVDDSWTVSELMLTVCTKLGIYNYDEYSLISDKMDFSPGIDKTLSMKRGISINXXXXXXXXXXXXYHTEDGLNWLNPSQSLRQQGIEESEVLLLKRKYFFSDMNVDSRDPIQLSLLYEQLKDAVINGTHPVTLPEAIELAGLQCQVQLGNYSADKFKPGFLDLRECLPKEYQKNPKTVEKKIFNQHSKSKDLSEVEAKEKYCLLCRSFKTYGITFFLVKEKVIGKNKLIPRLLGVNKESVVQVDEKTKEIINTWPLTSIRKWAASFNGFTMDFGEYSPDEYYTAQTDKGERISQLIAGYIDIILKRKKAKDHLGVDADEESIMYEENIAPSKAIIVEHVPKQKRSSVSEEDVVIRKKAHMANSSVRMNSQASDSVCSQDCTDFYQEDINMSRQTSSLGRTQSPSSS--LTTNSMHY-RMSDDDIRQKLYIISLQDNLDTIQKYKDQLMIENKGPEIGKDEASQQWIYVNIDNSRQRMADEIGAMNAAVAQVLRSAQGLATIXXXXXXXXXXXXIAKMQNSFSLITVHLPSLMEEIRTAAYYQDQLTDEDVSGEELIAAAKRLADAFTNLIKAAYPVEDQKRSLNRKEIFDAANAVGEASSDLLQQITEQENCQIELKSERPYSIIMITEEDQLYQEELLRLAKSVANETTNLIKQVKVIAVEAENPSDQKKVVMAATETGLAISQLISTTKIVAPTIEQSVCQEQLIFSIEDVSKAIQVVVESSNKATQSEELQDLTVQAANQVQEALDTLMKHLRXXXXXXXXXXXXXXAYENI----QEXXXXXXXXXXXXXXXRRLAQATTAMISEIQLKAVNEQYKTPEERDKLINAAKQLAEATTVLIDSAKNCTMDKDEMNLRYTLREATERFIVVTYTTECATYIQEQVIDHLLV--AARKAATTGTHLINTSLSAAKKSRASNFKVCNDGRELSNQISNLIVAIKEARRDPKDHLAQLELIAACRDYIDPSEQLSQSNKYMWPTVSDPSLQTALNQSINQSVIATEELKKCVHQADLMCQHLDLSAALEQLKRLEQNLKSIKNSIERENLIPLPDEKSDESAALLIKSVRRSGSAANQFKNDLESRCVVYEQTNGEDSYQNLENLDVAGQKARELSMALDRLVHAARGVAASIEFENQESENNDKNLEKLAQLQIVNNCLEAVKAARDLVIEAKSS---PPDNDQMDRAQQASVRXXXXXXXXXXXXPGQRDLDMLSKHIESKKHQFAENRLPIQQNNNINLSNCRSELTDTTFDFNQAVNELVSAP--SFNLVNKGCKKMRMSYDRIVEICNVLVHDPFDESDSALHHLSSNRDHIANGVMIMSEDCQTLLDKVKKIQCEPDNIIVRKQLQEATKMLLDSINRLLTNISTNLRPGQKECDKTIYRLESMRPILDNPVHPISHKDYFECLDFIIDKTVQPLADSLKNIPAAVKDENNQKFIDSIYHCADSVCMLLEETAQTAYLVGVGDVRSKIGNKGLADHTSFLQIQKEISENCQTICNP 4803
L+I + +V K + +P ++ C IR+ + EAQ P + L L P L + ++ T + D +EYR + R L +R +DGT KT VDDS TV +++L VC ++GI NY+EYSL+ + + +D T ++K+ S+ +D++K++KLK+K HT+D +NWL+ ++LR+QG+E+SE LLL+RK+F+SD NVDSRDP+QL+LLY Q +D ++NG+HPV+ A E AG Q Q+Q G ++ K KPGFLDL+E LPKEY K + EK++F +H K + ++E+EAK +Y RS KTYG++FFLVKEK+ GKNKL+PRL G+ KESV++VDE+TKE+I WPLT++++WAAS FT+DFG+YS D YY+ QT +GE+I+QLIAGYIDIILK+KK+KD G + DEES M E++++P K+ +++ + + + + +A +V + SLGR P ++ +T+ +MH + Q+ + ++ ++ +Q+ + L + P +G+D+AS+ W +D ++ + ++ A+NA+ A + G A + I+ S L +L EE E G L+ AA+ L D ++L+K P + R+ + AA+ VG +S++LL+QI +Q DQ +Q+ L +LAK+VAN L+ + K +A +A++ + Q +V+ AAT+ L+ SQL++ TK+V PT++ VCQEQL+ S + V++A++ V SS +AT+ +EL AA V +ALD L++H++ + + A + I + + S + ++V AR LAQAT+ +I+ I++ A E + E KL+ AAK LA+AT ++++AK + + + L+EA E V T I+++++ L V AA + T +A+ K+ A+ ++ + +++ + L+ + ++ P AQL LI A +++ P ++ + K PTV+D + L Q EL+ +A C L++ +AL+ ++ LE L+ K + L PLP E + A L + + GS+ Q V+ + G ++Y + D A + + A ++A +K Q ++ + + + A + EAK + P D R Q + +S AL C+ LPGQ+D+D + + + + +P + + + L D N + +ELV A S ++ +K + R ++ + + D + + +S LL K + +P+ + QL A + + DSIN+L+T + T PGQ ECD + LE+++ +LDNP P++ YFEC+D +++ + + L ++++ + K N F ++I + ++C L E +Q+AYLVGV D S+ G GL D F + + I CQ + +P
Sbjct: 4 LSLKICVRHCNVVKTMQFEPSTVVYDACRIIRERVPEAQDGQPPATPLALSSLPSPPRPLHLPISSTATSPPHPQ---DLLEYRKKQRPLKVRMLDGTIKTAMVDDSKTVGDMLLAVCARIGITNYEEYSLVREVAE-EKAMDGTGTLKKDRSLLRDEKKMEKLKQKLHTDDDMNWLDHGRTLREQGVEDSETLLLRRKFFYSDQNVDSRDPVQLNLLYVQARDDILNGSHPVSFEMACEFAGYQAQIQFGPHNEVKHKPGFLDLKEFLPKEYVKQ-RGAEKRLFQEHKKCESMTEIEAKVRYVRQARSLKTYGVSFFLVKEKMKGKNKLVPRLFGITKESVMRVDERTKEVIQEWPLTTVKRWAASPKSFTLDFGDYS-DGYYSVQTTEGEQIAQLIAGYIDIILKKKKSKDRFGTEGDEESTMLEDSVSPKKSTVIQ---------TNCNPMGMAEHGSVALPAVMRGIGGPE----------------------SLGRGVMPGANKVITSGAMHRGHLPPMSTNQQALMGTITSSMQAVQQAGNSLDEMDALPPLGQDKASKAWRQYKMDQAKHEIHSQVDAINASTASCINLTSGDAADTDYTAVGCAVVTISSNLTEMSRGVRLLAALTEE-------------EGGDGRALLQAARGLIDCISDLLKTVQPSSTEP----RQAVLTAASTVGRSSNNLLKQIGQQ-------------------GVDQQFQDVLNQLAKAVANAAAGLVLKAKTVAQKADDQALQNQVIAAATQCALSTSQLVACTKVVGPTMDSPVCQEQLMESGKLVARAVEGCVRSSQEATKDDELLRQVGGAAGAVTQALDALLQHVKLLASGGHGMGRYDCATDTIITATESIFSSTGNAGEMVKQARLLAQATSDLINAIKVDAEAEGDQ--ENSRKLLAAAKYLADATAKMVEAAKGAAANPESEEQQQRLQEAAEGLRVAT-NIAAQNAIRKKLVHRLEVAARQAAAAASQAIAAATQAAASNKNPANQQQLVGCSKNVADHVPQLVQGWRGSQSQPDSPSAQLALITASHNFLQPGTKMVAAAKASVPTVTDQASSMQLGQCAKNLATCLAELRTAAQKAQDACGTLEIDSALDLVRSLEAELQEAKVAASDGKLHPLPGETLETCAQDLGATSKTVGSSMAQ---------VMTAASQGNENYTGIAARDTAQALKQLAAAARGLAANSA---------------------DKPTQEAVLESARDLMDKASLFIQEAKKAVVRPGDPINQQRLAQVAKAVSGALGKCVGCLPGQQDVDTALRSLADHSKKLLSDTIP---RSGSSFQEAQGNLNDAAAGLNLSASELVQASRGSSQELSTASRKFGNDFSRFLDAGIDMAGQAKTKEDQV---------QVVGNLKSISMSSSKLLLAAKALCVDPNAPNAKNQLAAAARAVTDSINQLIT-MCTQQAPGQNECDNALRELETVKGMLDNPSEPVNDLSYFECIDSLMENS-KVLGEAMQGVSQNAKTSNLPAFGEAISSASKALCGLTEAASQSAYLVGVSDPNSQAGQPGLVDPGQFARANQAIQMACQNLVDP 1485
BLAST of Talin-1 vs. Ensembl Sea Lamprey
Match: mast2 (microtubule associated serine/threonine kinase 2 [Source:ZFIN;Acc:ZDB-GENE-050309-150]) HSP 1 Score: 621.313 bits (1601), Expect = 0.000e+0 Identity = 311/614 (50.65%), Postives = 418/614 (68.08%), Query Frame = 1
Query: 9589 NPCRSPGAYEQDIFILNHVYKERFPKATIQMMERLSAMLEELENENTVSW-EPISRLVHTQIMKHVKDILNMTNLEAITSTYFFELTQNLEKLLKETRLKCPES-LARVRPIVQHLLFIIARPARLLECIEFDPKEFYKLLEVAENNLR---NVQTDVPKYIISKLGLDKDPYDIGSEELNTSLELNGGSLEIXXXXXXXXXXXXXXXXXLNMSQESNNSLELSFSKSM---TPKESDFEDIKLISNGAYGAVHLVREKKTKKRFAMKKIRKDNLLLRNQVEQIFAERDIMTFADSPFVVGLYCTFETRKYLCMIMEYVEGGDVATLIKSIGPLPDELARMYFAETVLALEYLHNFGIVHRDLKPDNLLITLEGHIKLTDFGLSKVGLMNLTTTLLESVLNKDCTMFQDKQVFGTPDYIAPEVILRQGYDKMIDWWAMGIILYEFIVGCTPFYGDSTEELFGNIISGEIEWPQDPDPCVPDNAVNLITELLKRDPLVRLGAEGTHEVKEHEFFSDVDWQGLLRQKALFIPVLDHEDDTSYFDPRTSRYQHESESDDPDPGSGLGSXXXXXXNDETIEHCEXXXXXXXXXXXXXGTVFHAFPSCSPRFSRFVETE 11406
+P RSP Y+ +I ++NHVYKERFPKAT QM ERL ++ + E+T+ + + +H Q+++ +D L + ITS YF+EL +NLEKLL + + + + +A + + + LL +I+RPARLLEC+EFDP+EFY LLE AE + + +++D+P+YIIS+LGL +DP EE+ + G+ E + E++++ + ++S+ P E DFE IKLISNGAYGAV+LVR K+T++RFAMKKI K NL+LRNQ++Q F ERDI+TFA++PFVVG++C+FET+++LCM+MEYVEGGD ATL+K++G LP ++A++YFAETVLALEYLHN+GIVHRDLKPDNLLIT GH+KLTDFGLSK+GLM+LTT L E + KD F DKQV GTP+YIAPEVILRQGY K +DWWAMG+ILYEF+VGC PF+GD+ EELFG +IS EI WP+ D +P + +LIT LL+R+PL RLG G EVK+H+FF +DW GLLRQKA F+P L+ E+DTSYFD R+ RY H DD + ++E +E F SCSPRF + E
Sbjct: 1 SPGRSPSVYDNEIVMMNHVYKERFPKATAQMEERLQVLVAVNDPEDTLPLADGVLSFIHHQLIELARDCLAKSRTGQITSRYFYELQENLEKLLNDAQDRSESNEVAFITQLAKRLLIVISRPARLLECLEFDPEEFYHLLEAAEGHAKEDQGIKSDIPRYIISQLGLTRDPL----EEMAQLSSCDSGNPE---------------------TPETDDATDSRAAESLPKKKPCEEDFETIKLISNGAYGAVYLVRHKETRQRFAMKKINKQNLILRNQIQQAFVERDILTFAENPFVVGMFCSFETKRHLCMVMEYVEGGDCATLLKNLGALPVDMAQLYFAETVLALEYLHNYGIVHRDLKPDNLLITSMGHVKLTDFGLSKIGLMSLTTNLYEEHIEKDTREFLDKQVCGTPEYIAPEVILRQGYGKPVDWWAMGVILYEFLVGCVPFFGDTPEELFGQVISDEIVWPEGED-ALPSDVQDLITGLLERNPLERLGTGGAFEVKQHQFFHSLDWDGLLRQKAEFVPQLESEEDTSYFDTRSDRYHHLDSEDDTN-------------DEEPLE-------------------MRQFSSCSPRFKVYSSME 556 HSP 2 Score: 97.8265 bits (242), Expect = 4.668e-20 Identity = 46/101 (45.54%), Postives = 68/101 (67.33%), Query Frame = 1
Query: 12130 IVIHRRSRNFGFVIRAIRVFYGESNVYTLHHLIV--GVDPEGSAFQAGLREGDLITHINGVSIVGAYHTEVVSMIIQSGASISLRVIPINKSFIRTDGPWR 12426
+VIHR + +GF +RAIRV+ G+S+VY++HH++ V+ A +AGLR GDLITH+NG + G HTEVV +I++SG +S+ P + I+ GP R
Sbjct: 790 VVIHRAGKKYGFTLRAIRVYMGDSDVYSVHHVVWWQNVEEGSPANEAGLRAGDLITHVNGEPVHGLVHTEVVELILKSGYKVSIATTPFENTSIKV-GPAR 889
BLAST of Talin-1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007752.1 (pep scaffold:Pmarinus_7.0:GL478287:501:47681:-1 gene:ENSPMAG00000006982.1 transcript:ENSPMAT00000007752.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 397.127 bits (1019), Expect = 7.422e-116 Identity = 355/1209 (29.36%), Postives = 580/1209 (47.97%), Query Frame = 1
Query: 901 HSKSKDLSEVEAKEKYCLLCRSFKTYGITFFLVKEKVIGKNKLIPRLLGVNKESVVQVDEKTKEIINTWPLTSIRKWAASFNGFTMDFGEYSPDEYYTAQTDKGERISQLIAGYIDIILKRKKAKDHLGVDADEESIMYEENIAPSKAIIVEH----VPKQKRSSVSEEDVVIRKKAHMANSSVRMNSQASDSVCSQDCTDFYQEDINMSRQTSSLGRTQSPSSSLTTNSMH-YRMSDDDIRQKLYIISLQDNLDTIQKYKDQLMIENKGPEIGKDEASQQWIYVNIDNSRQRMADEIGAMNAAVAQVLRSAQGLATIXXXXXXXXXXXXIAKMQNSFSLITVHLPSLMEEIRTAAYYQDQLTDEDVSGEELIAAAKRLADAFTNLIKAAYPVEDQKRSLNRKEIFDAANAVGEASSDLLQQITEQENCQIELKSERPYSIIMITEEDQLYQEELLRLAKSVANETTNLIKQVKVIAVEAENPSDQKKVVMAATETGLAISQLISTTKIVAPTIEQSVCQEQLIFSIEDVSKAIQVVVESSNKATQSEELQDLTVQAANQVQEALDTLMKHLRXXXXXXXXXXXXXXAY-----------ENIQEXXXXXXXXXXXXXXXRRLAQATTAMISEIQLKAVNEQYKTPEERDKLINAAKQLAEATTVLIDSAKNCTMDKDEMNLRYTLREATERFIVVTYTTECATYIQEQVIDHLLVAARKAATTGTHLINTSLSAAKKSRASNF--KVCNDGRELSNQISNLIVAIKEARRDPKDHLAQLELIAACRDYIDPSEQLSQSNKYMWPTVSDPSLQTALNQSINQSVIATEELKKCVHQADLMCQHLDLS-AALEQLKRLEQNLKSIKNSIERENLIPLPDEKSDESAALLIKSVRRS-GSAANQFKNDLESRCVVYEQTNGEDSYQNLENLDVAGQKARELSMALDRLVHAARGVAASIEFENQESENNDKNLEKLAQLQIVNNCLEAVKAARDLVIEAKSSPPDNDQMDRAQQASVRXXXXXXXXXXXXPGQRDLDMLSKHIESKKHQFAENRLPIQQNNNINLSNCRSELTDTTFDFNQAVNELVSAPSFNLVNKGCKKMRMSYDRIVEICNVLVHDPFDES--DSALHHLSSNRDHIANGVMIMSEDCQTLLDKVKKIQCEPDNIIVRKQLQEATKMLLDSINRLLTNISTNLRPGQKECDKTIYRLE 4461
H + + +E+ AK KY L RS +TYG++FFLVKEK+ KNKL+PRLLGV KESV++VDE+TKE++ WPLT++++WAAS FT+DFG+Y YY+ QT +GE+ISQLIAGYIDIILK+K+AKD G++ DEES M EE+++P K+ I++ V K + +SV+ ++ R + D+V + G +T+ MH M Q+ + ++ ++ +Q+ L + P +G D SQ W +D S+ + ++ A+ A A V+ G + + + + + I+ +L + + +R A D DE +G++L+ AA+ LA A ++L+K P + R + + AA VG+AS +LL+ I E E DQ +Q+ L++LAK+VAN L+ + K +A AE+P+ Q +V+ AAT+ L+ SQL++ TK+V PTI CQEQL+ + + V++A++ V++S AT+ EEL +AA V +AL+ L++H+R+ +Y ENI S D ++V AR LAQAT+ +++ I+ A EQ + E L+ AA+ LA+AT ++++AK + + + LREA E V T I++++ + L AA++AA T I + AA +++ N ++ + +++ I L+ +++E++ P AQ LI + ++ P L S + P+V + + L EL+ H+A C + +AL ++ LE L+ K + + L PLP E + ES +L + S ++ GSA Q + + G++S+ + + A + A + A +A E + DK+ N EA KAA A S PDN Q R Q + +S AL+ C++SLPGQ+D+D ++I + + P + + +S LT NQA +V A + R D D D + L ++ + + +S LL K + +P V+ QL A + + DSIN LL ++ T PGQ+ECD + +LE
Sbjct: 3 HKECGEFNEITAKSKYVKLARSLRTYGVSFFLVKEKMKSKNKLVPRLLGVTKESVLRVDERTKEVMQEWPLTTVKRWAASPKSFTLDFGDYQVG-YYSVQTTEGEQISQLIAGYIDIILKKKQAKDRFGLEGDEESTMLEESVSPKKSTILQQQYNRVGKVEHASVALPAIM------------RPGAGGPDTV--------------------NWGMMPVAQQQVTSGQMHKGHMPPLSSAQQALVGTITSSMQAVQQAHGDLGDMDSLPPLGDDAESQSWRRNKMDESKHEIHSQVDAITAHTASVVNLTAG----------DPADTDYTAVGCAVTTISSNLTEMSKGVRLLAALLD---DEGANGQDLMQAARGLASAVSDLLKTVDPSTAEPR----QSVLTAAGNVGQASGELLRTIGEDE-------------------ADQSFQDMLMQLAKAVANAAATLVLKAKNVAQRAEDPAQQNRVIAAATQCALSTSQLVACTKVVGPTIRSPACQEQLMEAGKLVARAVEGCVQASQDATEEEELLRQVGEAATAVTQALNDLLRHVRQYAASLTGRAGPGGSYVQATDTILTATENI---FGSMGDAGEMVRQARLLAQATSDLVNAIKADAEAEQDQ--ENVRNLLAAARVLADATARMVEAAKGAAANPENEEQQQKLREAAEGLRVATNIA-AQNAIKKKLTNRLEQAAKQAAAASTQTIAAAQHAASSNKSPNSQQQLVQSCKVVADHIPQLVQSVRESQSTPDSQQAQQSLITSSLGFLQPGNHLVASARAAVPSVENQASSNQLGTCAKNLAACLSELRAAAHKAQQACSPTEGQDSALALVRALENELEEAKTEVAQGRLKPLPGE-TLESCSLELGSASKTVGSAIAQL---------LTAASQGDESFTDHAAHEAAEALRGLAAAARGVAANTADPLAQEAALETAR-DVMDKS---------ANLLQEARKAA------ANPSDPDNQQ--RLAQVAKAVSLALNNCVNSLPGQKDVDSALRNINDASKRLQADSFP---QSGRSYHEAQSGLTQAAAGLNQATGRVVHASHGSSRELATASGRFGRD---------FSDFLDAGIEMAGLTQTKEDQVQVIGNLKNISVSSSKLLMAAKSMVIDPAAPNVKNQLASAARAVTDSIN-LLISMCTQQAPGQRECDNALRQLE 1095
BLAST of Talin-1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000003561.1 (pep scaffold:Pmarinus_7.0:GL478057:5187:43749:1 gene:ENSPMAG00000003167.1 transcript:ENSPMAT00000003561.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 230.335 bits (586), Expect = 1.839e-60 Identity = 128/316 (40.51%), Postives = 185/316 (58.54%), Query Frame = 1
Query: 10267 KESDFEDIKLISNGAYGAVHLVREKKTKKRFAMKKIRKDNLLLRNQVEQIFAERDIMTFADSPFVVGLYCTFETRKYLCMIMEYVEGGDVATLIKSIGPLPDELARMYFAETVLALEYLHNFGIVHRDLKPDNLLITLEGHIKLTDFGLSKVGLMNLTTTLLESVLNKDCTMFQDKQVFGTPDYIAPEVILRQG----YDKMIDWWAMGIILYEFIVGCTPFYGDSTEELFGNII--SGEIEWPQDPDPCVPDNAVNLITELLKRDPLVRLGAEGTHEVKEHEFFSDVD--WQGLLRQKALFIPVLDHEDDTSYFD 11190
+ +D++ +K+I GA+G V LVR K TKK +AMK + K + R+ + ERDIM FA+SP+VV L+ F+ +YL M+MEY+ GGD+ L+ + +P++ AR Y AE VLAL+ +H+ G +HRD+KPDN+L+ GH+KL DFG M + T E ++ D + GTPDYI+PEV+ QG Y + DWW++G+ LYE +VG TPFY DS + I+ + +P D D + +A NLI L D VR+G G E+K H FF + W+ + A +P L + DTS FD
Sbjct: 72 RANDYDVVKVIGRGAFGEVQLVRHKATKKVYAMKLLSKFEMTKRSDSAFFWEERDIMAFANSPWVVQLFYAFQDHRYLYMVMEYMPGGDLVNLMSNYD-VPEKWARFYTAEVVLALDAIHSMGFIHRDVKPDNMLLDKNGHLKLADFGT----CMKMDT---EGMVRCDTAV-------GTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMDHKNALNFPDDVD--ISKDAKNLICAFLI-DREVRVGRNGVGEIKRHPFFKNDQWTWENIRETAAPVVPELVSDTDTSNFD 369
BLAST of Talin-1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004595.1 (pep scaffold:Pmarinus_7.0:GL477044:11103:63873:-1 gene:ENSPMAG00000004137.1 transcript:ENSPMAT00000004595.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 229.95 bits (585), Expect = 2.046e-60 Identity = 133/339 (39.23%), Postives = 203/339 (59.88%), Query Frame = 1
Query: 10276 DFEDIKLISNGAYGAVHLVREKKTKKRFAMKKIRKDNLLLRNQVEQIFAERDIMTFADSPFVVGLYCTFETRKYLCMIMEYVEGGDVATLIKSIGPLPDELARMYFAETVLALEYLHNFGIVHRDLKPDNLLITLEGHIKLTDFGLSKVGLMNLTTTLLESVLNKDCTMFQDKQVFGTPDYIAPEVILRQG----YDKMIDWWAMGIILYEFIVGCTPFYGDSTEELFGNIISGE--IEWPQDPDPCVPDNAVNLITELL-KRDPLVRLGAEGTHEVKEHEFFSDVD--WQGLLRQKALFIPVLDHEDDTSYFDPRTSRYQHESESDD--PDPGSGLGS 11259
D++ +K+I GA+G V LVR K TK +AMK + K ++ R+ + ERDIM FA+SP++V L+ +F+ +YL M+MEY+ GGD+ L+ + +P++ AR Y AE VLA++ +H+ G +HRD+KPDN+L+ GH+KL DFG T ++ LNKD + D V GTPDYI+PEV+ QG Y + DWW++G+ L+E +VG TPFY +S +G I+ + + +P D D + NA +LI L +RD VRLG G E+K H+FF + W+ + A +P L + DTS FD +++ +D+ P P + +G+
Sbjct: 46 DYDSVKVIGRGAFGEVQLVRHKVTKSVYAMKLLNKLEMIKRSDSAFFWEERDIMAFANSPWIVQLFYSFQDDRYLYMVMEYMPGGDLVNLMSNYD-VPEKWARFYTAEVVLAVDAIHSMGYIHRDVKPDNMLLDKSGHLKLADFG-----------TCMK--LNKDGMVRCDTAV-GTPDYISPEVLRSQGGQGYYGRECDWWSVGVFLFEMLVGDTPFYAESLVGTYGKIMDHKKSLTFPVDLD--ISKNAKSLICAFLTERD--VRLGKNGFAEIKCHDFFKNDQWTWENIRETSAPVVPELSSDTDTSNFDE----IENDKSADETFPQPKAFVGN 361
BLAST of Talin-1 vs. Ensembl Yeast
Match: KIN82 (Putative serine/threonine protein kinase; implicated in the regulation of phospholipid asymmetry through the activation of phospholipid translocases (flippases); involved in the phosphorylation of upstream inhibitory kinase Ypk1p along with Fpk1p; has a redundant role in the cellular response to mating pheromone; KIN82 has a paralog, FPK1, that arose from the whole genome duplication [Source:SGD;Acc:S000000687]) HSP 1 Score: 234.958 bits (598), Expect = 1.241e-64 Identity = 117/308 (37.99%), Postives = 186/308 (60.39%), Query Frame = 1
Query: 10258 MTPKESDFEDIKLISNGAYGAVHLVREKKTKKRFAMKKIRKDNLLLRNQVEQIFAERDIMTFADSPFVVGLYCTFETRKYLCMIMEYVEGGDV--ATLIKSIGPLPDELARMYFAETVLALEYLHNFGIVHRDLKPDNLLITLEGHIKLTDFGLSKVGLMNLTTTLLESVL--NKDCT-MFQDKQVFGTPDYIAPEVILRQGYDKMIDWWAMGIILYEFIVGCTPFYGDSTEELFGNIISGEIEWPQDPDPCVPDNAVNLITELLKRDPLVRLGAE-GTHEVKEHEFFSDVDWQGLLRQKALFIPVLD 11163
+T + FE I+L+ G G V+LVRE+ T + FA+K + K ++ R +++++ E++I+ +D PF+V LY +F+T+ YL + MEY GG+ A + + +E A+ Y +E V ALEYLH G ++RDLKP+N+L+ GH+ L+DF LS + T+ +S K C+ F+ GT +Y+APEVI G+ +DWW +GI++YE + GCTPF GD++ E F NI++ ++++P D + V N +LI +LL ++ RLG++ G ++K H FF V W L Q IP L+
Sbjct: 317 ITVEPQSFEKIRLLGQGDVGKVYLVRERDTNQIFALKVLNKHEMIKRKKIKRVLTEQEILATSDHPFIVTLYHSFQTKDYLYLCMEYCMGGEFFRALQTRKSKCIAEEDAKFYASEVVAALEYLHLLGFIYRDLKPENILLHQSGHVMLSDFDLSIQATGSKKPTMKDSTYLDTKICSDGFRTNSFVGTEEYLAPEVIRGNGHTAAVDWWTLGILIYEMLFGCTPFKGDNSNETFSNILTKDVKFPHDKE--VSKNCKDLIKKLLNKNEAKRLGSKSGAADIKRHPFFKKVQWSFLRNQDPPLIPALN 622
BLAST of Talin-1 vs. Ensembl Yeast
Match: TPK3 (cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk2p; localizes to P-bodies during stationary phase; TPK3 has a paralog, TPK1, that arose from the whole genome duplication [Source:SGD;Acc:S000001649]) HSP 1 Score: 223.787 bits (569), Expect = 4.595e-64 Identity = 115/314 (36.62%), Postives = 192/314 (61.15%), Query Frame = 1
Query: 10273 SDFEDIKLISNGAYGAVHLVREKKTKKRFAMKKIRKDNLLLRNQVEQIFAERDIMTFADSPFVVGLYCTFETRKYLCMIMEYVEGGDVATLIKSIGPLPDELARMYFAETVLALEYLHNFGIVHRDLKPDNLLITLEGHIKLTDFGLSKVGLMNLTTTLLESVLNKDCTMFQDKQVFGTPDYIAPEVILRQGYDKMIDWWAMGIILYEFIVGCTPFYGDSTEELFGNIISGEIEWPQDPDPCVPDNAVNLITELLKRDPLVRLG--AEGTHEVKEHEFFSDVDWQGLLRQKALFI------PVLDHEDDTSYFD 11190
SDF+ ++ + G++G VHL+R + +A+K ++K ++ QVE ER +++ PF++ ++ TF+ + + M+M+Y+EGG++ +L++ P+ +A+ Y AE LALEYLH+ I++RDLKP+N+L+ GHIK+TDFG +K + ++T TL C GTPDYIAPEV+ + Y+K +DWW+ G+++YE + G TPFY +T + + NI++ E+++P P +A +L+ +L+ RD RLG G+ +VK H +F++V W+ LL A +I P+ + DTS FD
Sbjct: 86 SDFQILRTLGTGSFGRVHLIRSNHNGRFYALKTLKKHTIVKLKQVEHTNDERRMLSIVSHPFIIRMWGTFQDSQQVFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKNGHIKITDFGFAKY-VPDVTYTL--------C---------GTPDYIAPEVVSTKPYNKSVDWWSFGVLIYEMLAGYTPFYNSNTMKTYENILNAELKFP----PFFHPDAQDLLKKLITRDLSERLGNLQNGSEDVKNHPWFNEVIWEKLL---ARYIETPYEPPIQQGQGDTSQFD 374
BLAST of Talin-1 vs. Ensembl Yeast
Match: TPK1 (cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; inhibited by regulatory subunit Bcy1p in the absence of cAMP; phosphorylates and inhibits Whi3p to promote G1/S phase passage; partially redundant with Tpk2p and Tpk3p; phosphorylates pre-Tom40p, which impairs its import into mitochondria under non-respiratory conditions; TPK1 has a paralog, TPK3, that arose from the whole genome duplication [Source:SGD;Acc:S000003700]) HSP 1 Score: 222.246 bits (565), Expect = 1.232e-63 Identity = 115/310 (37.10%), Postives = 188/310 (60.65%), Query Frame = 1
Query: 10276 DFEDIKLISNGAYGAVHLVREKKTKKRFAMKKIRKDNLLLRNQVEQIFAERDIMTFADSPFVVGLYCTFETRKYLCMIMEYVEGGDVATLIKSIGPLPDELARMYFAETVLALEYLHNFGIVHRDLKPDNLLITLEGHIKLTDFGLSKVGLMNLTTTLLESVLNKDCTMFQDKQVFGTPDYIAPEVILRQGYDKMIDWWAMGIILYEFIVGCTPFYGDSTEELFGNIISGEIEWPQDPDPCVPDNAVNLITELLKRDPLVRLG--AEGTHEVKEHEFFSDVDWQGLLRQK---ALFIPVLDHEDDTSYFD 11190
DF+ ++ + G++G VHL+R + + +AMK ++K+ ++ QVE ER +++ PF++ ++ TF+ + + MIM+Y+EGG++ +L++ P+ +A+ Y AE LALEYLH+ I++RDLKP+N+L+ GHIK+TDFG +K + ++T TL C GTPDYIAPEV+ + Y+K IDWW+ GI++YE + G TPFY +T + + I++ E+ +P P ++ +L++ L+ RD RLG GT +VK H +F +V W+ LL + P+ + DTS FD
Sbjct: 86 DFQILRTLGTGSFGRVHLIRSRHNGRYYAMKVLKKEIVVRLKQVEHTNDERLMLSIVTHPFIIRMWGTFQDAQQIFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKNGHIKITDFGFAKY-VPDVTYTL--------C---------GTPDYIAPEVVSTKPYNKSIDWWSFGILIYEMLAGYTPFYDSNTMKTYEKILNAELRFP----PFFNEDVKDLLSRLITRDLSQRLGNLQNGTEDVKNHPWFKEVVWEKLLSRNIETPYEPPIQQGQGDTSQFD 373
BLAST of Talin-1 vs. Ensembl Yeast
Match: TPK2 (cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk3p; localizes to P-bodies during stationary phase; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000006124]) HSP 1 Score: 214.927 bits (546), Expect = 2.645e-61 Identity = 113/326 (34.66%), Postives = 191/326 (58.59%), Query Frame = 1
Query: 10276 DFEDIKLISNGAYGAVHLVREKKTKKRFAMKKIRKDNLLLRNQVEQIFAERDIMTFADSPFVVGLYCTFETRKYLCMIMEYVEGGDVATLIKSIGPLPDELARMYFAETVLALEYLHNFGIVHRDLKPDNLLITLEGHIKLTDFGLSKVGLMNLTTTLLESVLNKDCTMFQDKQVFGTPDYIAPEVILRQGYDKMIDWWAMGIILYEFIVGCTPFYGDSTEELFGNIISGEIEWPQDPDPCVPDNAVNLITELLKRDPLVRLG--AEGTHEVKEHEFFSDVDWQGLLR---QKALFIPVLDHEDDTSYFDPRT-SRYQHESESDDP 11235
DF+ ++ + G++G VHLVR + +A+K ++K ++ QVE ER ++ + PF++ ++ TF+ + + M+M+Y+EGG++ +L++ P+ +A+ Y AE +LALEYLH I++RDLKP+N+L+ GHIK+TDFG +K + +T TL C GTPDYIAPEVI + Y+K +DWW++G+++YE + G TPFY + + + I+ G++ +P P + V+L+++L+ D R+G G+ ++K H +FS+V W+ LL + P+ DTS FD + + + DDP
Sbjct: 69 DFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKQQVVKMKQVEHTNDERRMLKLVEHPFLIRMWGTFQDARNIFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVILALEYLHAHNIIYRDLKPENILLDRNGHIKITDFGFAK-EVQTVTWTL--------C---------GTPDYIAPEVITTKPYNKSVDWWSLGVLIYEMLAGYTPFYDTTPMKTYEKILQGKVVYP----PYFHPDVVDLLSKLITADLTRRIGNLQSGSRDIKAHPWFSEVVWERLLAKDIETPYEPPITSGIGDTSLFDQYPEEQLDYGIQGDDP 372
BLAST of Talin-1 vs. Ensembl Yeast
Match: FPK1 (Ser/Thr protein kinase; phosphorylates several aminophospholipid translocase family members, regulating phospholipid translocation and membrane asymmetry; phosphorylates and inhibits upstream inhibitory kinase, Ypk1p; localizes to the cytoplasm, early endosome/TGN compartments and thplasma membrane; localizes to the shmoo tip where it has a redundant role in the cellular response to mating pheromone; FPK1 has a paralog, KIN82, that arose from the whole genome duplication [Source:SGD;Acc:S000005330]) HSP 1 Score: 228.024 bits (580), Expect = 2.957e-61 Identity = 119/305 (39.02%), Postives = 185/305 (60.66%), Query Frame = 1
Query: 10279 FEDIKLISNGAYGAVHLVREKKTKKRFAMKKIRKDNLLLRNQVEQIFAERDIMTFADSPFVVGLYCTFETRKYLCMIMEYVEGGDV--ATLIKSIGPLPDELARMYFAETVLALEYLHNFGIVHRDLKPDNLLITLEGHIKLTDFGL------SKVGLM--NLTTTLLESVLNKDCTMFQDKQVFGTPDYIAPEVILRQGYDKMIDWWAMGIILYEFIVGCTPFYGDSTEELFGNIISGEIEWPQDPDPCVPDNAVNLITELLKRDPLVRLGAE-GTHEVKEHEFFSDVDWQGLLRQKALFIPVL 11160
FE I+L+ G G V LVREKKT + +A+K + KD ++ RN+++++ E++I+ ++ PF+V LY +F++ YL + MEY GG+ A + + ++ AR Y +E ALEYLH G ++RDLKP+N+L+ GHI L+DF L SKV ++ + +TL+++ + D F+ GT +YIAPEVI G+ +DWW +GI++YE + G TPF GD+T E F NI+ E+ +P + + + +LI +LL ++ RLG + G +VK+H FF V W L Q+ IPVL
Sbjct: 496 FEKIRLLGQGDVGKVFLVREKKTNRVYALKVLSKDEMIKRNKIKRVLTEQEILATSNHPFIVTLYHSFQSEDYLYLCMEYCMGGEFFRALQTRKTKCICEDDARFYASEVTAALEYLHLLGFIYRDLKPENILLHQSGHIMLSDFDLSIQAKDSKVPVVKGSAQSTLVDTKICSDG--FRTNSFVGTEEYIAPEVIRGNGHTAAVDWWTLGILIYEMLFGFTPFKGDNTNETFTNILKNEVSFPNNNE--ISRTCKDLIKKLLTKNESKRLGCKMGAADVKKHPFFKKVQWSLLRNQEPPLIPVL 796
BLAST of Talin-1 vs. Ensembl Nematostella
Match: EDO47777 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RL15]) HSP 1 Score: 926.776 bits (2394), Expect = 0.000e+0 Identity = 687/2304 (29.82%), Postives = 1207/2304 (52.39%), Query Frame = 1
Query: 49 FELRIHIVDADVTKIVPLDPEATIFQLCETIRKNIREAQTKSPKSYGLYLPHDDLKKGLWLDNSKTLQHYILKRGDTIEYRNRSRWLHIRTMDGTNKTLKVDDSWTVSELMLTVCTKLGIYNYDEYSL-ISDKMDFSPGIDKTLSMKRGISIN--------XXXXXXXXXXXXYHTEDGLNWLNPSQSLRQQGIEESEVLLLKRKYFFSDMNVDSRDPIQLSLLYEQLKDAVINGTHPVTLPEAIELAGLQCQVQLGNYSADKFKPGFLDLRECLPKEYQKNPKTVEKKIFNQHSKSKDLSEVEAKEKYCLLCRSFKTYGITFFLVKEKVIGKNKLIPRLLGVNKESVVQVDEKTKEIINTWPLTSIRKWAASFNGFTMDFGEYSPDEYYTAQTDKGERISQLIAGYIDIILKRKKAKDHLGVDADEESIMYEENIAPSKAIIVEHVPKQKRSSVSEEDVVIRKKAHMANSSVRMNSQASDSVCSQDCTDFYQEDINMSRQTSSLGRTQSPSSSLTTNSMH--YR---MSDDDIRQKLYIISLQDNLDTIQKYKDQLMIENKGPEIGKDEASQQWIYVNIDNSRQRMADEIGAMNAAVAQVLRSAQGLATIXXXXXXXXXXXXIAKMQNSFSLITVHLPSLMEEIRTAAYYQDQLTDEDVSGEELIAAAKRLADAFTNLIKAAYPVEDQKRSLNRKEIFDAANAVGEASSDLLQQITEQENCQIELKSERPYSIIMITEEDQLYQEELLRLAKSVANETTNLIKQVKVIAVEAENPSDQKKVVMAATETGLAISQLISTTKIVAPTIEQSVCQEQLIFSIEDVSKAIQVVVESSNKATQSE-ELQDLTVQAANQVQEALDTLMKHLRXXXXXXXXXXXXXXAYENI----QEXXXXXXXXXXXXXXXRRLAQATTAMISEIQLKAVNEQYKTPEERDKLINAAKQLAEATTVLIDSAKNCTMDKDEMNLRYTLREATERFIVVTYTTECATYIQEQVIDHLLVAARKAATTGTHLINTSLSAAKKSR--ASNFKVCNDGRELSNQISNLIVAIKEARRDPKDHLAQLELIAACRDYIDPSEQLSQSNKYMWPTVSDPSLQTALNQSINQSVIATEELKKCVHQADLMCQHLDLSAALEQLKRLEQNLKSIKNSIERENLIPLPDEKSDESAALLIKSVRRSGSAANQFKNDLESRCVVYEQTNGEDSYQNLENLDVAGQKARELSMALDRLVHAARGVAASIEFENQESENNDKNLEKLAQLQIVNNCLEAVKAARDLVIEAKSS---PPDNDQMDRAQQASVRXXXXXXXXXXXXPGQRDLDMLSKHIES-----KKHQFAENRLPIQQNNNINLSNCRSELTDTTFDFNQAVNELVSAP--SFNLVNKGCKKMRMSYDRIVEICNVLVHDPFDESDSALHHLSSNRDHIANGVMIMSEDCQTLLDKVKKIQCEPDNIIVRKQLQEATKMLLDSINRLLTNISTNLRPGQKECDKTIYRLESMRPILDNPVHPISHKDYFECLDFIIDKTVQPLADSLKNIPAAVKDENNQKFIDSIYHCADSVCMLLEETAQTAYLVGVGDVRSKIGNKGLADHTSFLQIQKEISENCQTICNPDTTARQDSSLMISTAGQIAENSRKLCEASK--TIMISFPNDKIKLSDKTKITLLAVSELMTGVQNLNQNFNEDNRKEVESLSGKVQDNVAELVQLLLSYKFAGDAAIISEEAKESQGPIKAAGITVLDTAIEVIQCSKALISSEANEELFIAYSSSCKDLNDALKHLISTIKESAPGQKECD---EXXXXXXXXXXQAYDSKMKIMKHRSRTISRTFESEESYQNILQSALIQMPHCINELSRAGKKEPEQLARIFSRQTQLLESMVNSCICAANQTDLIQNS---NIYLEHLITILEASEQLLKAVKKSGGNPKANSVHSQIDEMAQGVIESCEDLLAALDKISFKQGNVNTIVETITKSSAKVQESAIIPEKSR----FGNSQSKMLDICYDMNNLTTDISSNANSESTQRLLAPLTQNLTQRYDDLCRACQGAVATLSNENNGKQLQECVQTVGKVSISLVKSTTEVR--PSVASSISNLQAKTQELHKRIDDVIQLLISSNVGTQACTQAIKILKEINSDIDTSILFVKSADIQNDDREYYSVKELFKKSRNSVIDNSSELVRNIKLIVSKDVCDVNILQESADQIAITSQSLANDVKVGLEHLNSSTSQYNIELLVSFQEVIVSLISFLEVARNTSGLPYTDPLFQNLKEEGKCSINAITSLLKVLKSMDDVNLKDFQAIDNA 6825
L+I++V + K + +PEAT+ + IR+ + +A YGL+ DD KG WL+ ++++ Y LK GD +EY+++ R + I+ MDG KTL++DDS TV +++ TVC K+GI N +E+SL + K D +KT ++KR + + +D++K+D+LKKK HTED + WL+ ++LR+QG ++S ++++RKYF+SD NVD +DP+QL+LLY Q +D +++GTHP T EA +L +Q QVQ G+Y K+K +DL+E LPKEY K+ K ++KKI +H K L E++ + KY LCR KTYG+TFFLVKEK+ GKNKL+PRLLG+ KES+++VDEKTKE++ TWPLT++R+WAAS N FT+DFG+Y+ + YY+ QT++GE+ISQLIAGYIDIILK++K + D DE S M E+ +APSK + D K H + SV + A Q + + S+G+ + + S H +R + + Q+ Y+ SL +D++ ++L +G D AS +W +D SRQ +A + A++A+ A ++ G E + + +I+ +L L + I+ A D D +L+ AA+ LA AF+ L+KAA + R ++ +AA VG + + LL+ + E E DQ QE LL+LA++VAN T L+ + K +A + + + Q KV+ AA +T + SQL++ K+V P+I +CQEQ++ S + V+KA++ + A + E ++ + AA V++AL+ L+K +R+ ++ + + + ++I + +S + ++V A+ LAQAT++++S I+ +A E + + +L+ AAK LA+AT L+++AK + ++ + + L+ A E T T + ++++++ L AA++A T L+ + +AA +R AS ++ + + + +QI+ L+ ++++ +P D +QL LI + +I P +L +K PT+ +P + L + + EL+ +A C L++ +AL++LK L+ +LK+++ + E L+PLP E + SA L + + GS+ Q + G +SY G AR+ + AL L A RGVAA +K AQ IV ++ + L+ EAK + P D + R Q + +S AL+ C++ LPGQR+++ K + + K +F P Q+N + +L+ + N A +++VSA S N + K +SY +V +L DE + ++ + + S LL + + +P+ + L A + + DSIN LL N + PGQKECD + ++++ ILDNPV P++ YF+CL+ + K+ + L +++ I ++K + KF SI +++VC L E AQ AYLV V D S G GL D F+ ++EI++ CQ++ NPD++ ++ +++ A +A+++ LC A K + P K + K + L+ ++ N N+DNRK S + ++++V L LS FA A IS+EA+ +Q P+ AG ++ ++ +K + + + + + K + DA++ LI+ IK++APGQ+ECD E + + + QA + RT + + YQ + L +M + L A K +PE + + ++ T L + ++ I AA+ L++NS L+ T+ E++ Q++ A K +GGNP+ + H +DE AQ + ++ DL +++ + + G V+ +V++I+K+ ++ ++ + F Q +M D+ D+ ++++ T+ L PL ++++ YDD+ +GAVAT+ N + +++ VQ +G+ I LV+S V+ P+ S +L +++++ +++ ++ LI+ + GTQAC A ++ I SD+DT+++F + + + + E F R ++ + LV + K +V+ ++L +A+ + L + VK+G + S S LL + ++V +L S + +N SG DP + LK K ++ ++SLL +K+++D ++ +A++++
Sbjct: 3 LSLKINVVKNNSIKTLQFNPEATVAEALRIIREKVPDASPGKVADYGLFKQEDDPAKGKWLEPARSINFYPLKDGDMLEYKSKIRLIKIKFMDGNVKTLQIDDSHTVGQILETVCVKMGISNPEEFSLLVEGKDDEKEEAEKTSTLKRVMMKDVPIKRLEERDRKKMDQLKKKLHTEDDVQWLDHDKTLREQGTDDSHTVVMRRKYFYSDQNVDIKDPVQLNLLYVQCRDGILDGTHPCTQEEASQLGAIQIQVQFGDYEESKYK--LIDLKEVLPKEYVKS-KNIDKKIKEEHRKFNGLDELQGRYKYVQLCRGLKTYGVTFFLVKEKMKGKNKLVPRLLGITKESILRVDEKTKEVMKTWPLTTVRRWAASPNSFTLDFGDYT-ESYYSVQTNEGEKISQLIAGYIDIILKKRKGMEGYDPDFDEVSAMEEDQVAPSKGTYL--------------DRQTNKVGHASVGSVAL--PAVVRAGGQGSSRY------------SMGKMEPAQYGTVSGSAHSAHRPPMLHNLTPAQQAYMSSLSQGIDSVDTADEELKRPVNIVALGSDPASLKWKQNTLDVSRQNVASRLAALSASCASIVNVTSG----------EPGDTNYTAAGAAVHVISANLQDLSKGIKLIAGLLDNQDDS----SKLLDAARGLAGAFSLLLKAAQEGAGGDKE-KRSQLLNAAGNVGSSGAQLLEYMGE-------------------PEVDQETQETLLKLAQAVANATATLVLKAKNVASQCPDTAQQNKVIGAAKDTAMTTSQLVACVKLVVPSITSQMCQEQVVESAKQVAKAVEDTEGACKGACDPDSENMNVLIDAAQGVRDALNALLKKVREGGERPTEGEKYGETCDDILGATDRLFNSMGNAGEMVKQAKILAQATSSLVSGIKSEA--EVQDDDDNQKRLLAAAKLLADATAKLVEAAKGAARNPNDADEQEKLKRAAEDLRSAT-NTAASDALKKKLVKRLENAAKEATGQTTQLVAAAQAAAPVNRNQASQQQLMDQLKPVEDQIARLLESLRDCSNNPDDANSQLNLINVSKMFIPPVAKLVAFSKAALPTIDEPMYASQLGNFSKSTAASLNELRNAAEKAAEACGTLEVDSALKRLKALDDDLKAVERAAEEGKLVPLPGENPESSALELGATSKTVGSSMAQL---------LTAAAQGNESY--------TGIAARDTANALKNLTQAVRGVAAGTS-------------DKDAQKNIVQAARGVIQESAKLINEAKKALNNPGDPNNQQRLAQVAKGVSQALNNCVNCLPGQREVEDSIKAVSAASQALSKEEFPPTTEPYQRN--------QEKLSQSGAALNAAASDVVSASRGSPNQLATSTKNFSLSYQGLVNSGLMLAGQAPDE---------AAKEALVRNLRNTSTASSKLLLAARSLVSDPNAPNAKNALANAARAVTDSINTLL-NACMSAAPGQKECDSALRNIQAVNTILDNPVEPVNDSTYFDCLETVAGKS-KDLTEAMPVIADSIKQADYNKFDRSIKRASNAVCALTETAAQAAYLVAVADPSSVAGKPGLIDQEQFINAKQEINDACQSLLNPDSSQQR----VLAAATAVAKHTSALCNACKVASAKTHEPAAKRQFVQAAKDVANNTANLVKQIKTFAGNMNDDNRKSCASATRPLRNSVESLTAYALSPDFAPVPAKISDEARSAQVPVIMAGKSIANSGANYFNAAKLSVVNPQDTNAWQNLQQTAKQVADAMRRLITAIKDNAPGQRECDLAIEDINTVINNLDQA-----SLANISDGLEPRTEQPLQVYQERMMQNLGEMNPVVEPLGVAAKSQPENIGHLVAKMTDFLVPLCDAAIGAAS---LMKNSKRKGDLLDQTKTVAESAAQMMYATKTAGGNPQVHHAHPAVDEAAQSMHDAIYDLKNTIEQDASESGIVSGLVDSISKTLSESPYDSVDAYRRGAYEPFVVYQERMTKAMKDLVRKAQDMVGKSSTDPTK--LGPLAKDISNLYDDIAHNARGAVATVGNADVAGRIRNGVQGLGESCIGLVQSAGAVQATPTDPYSKKDLADRSRQVAEKVSHLLAALITGSRGTQACINAASTVQGIVSDLDTTVMFATAGTLNPE-----TPGETFADHREDILRTAKVLVEDTKRLVASAQASQDVLATAAESSVGSVSKLTDHVKLGAAAMGSDDSDAQQMLLNAARDVASALGSLINSTKNASGKSPNDPAMEPLKSSAKTMVSNVSSLLMTVKTVEDKTMRGTRAMESS 2169
BLAST of Talin-1 vs. Ensembl Nematostella
Match: EDO42523 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S134]) HSP 1 Score: 563.148 bits (1450), Expect = 4.099e-178 Identity = 279/555 (50.27%), Postives = 387/555 (69.73%), Query Frame = 1
Query: 9568 KPRSQSLNPCRSPGAYEQDIFILNHVYKERFPKATIQMMERLSAMLEELENE---NTVSWEPISRLVHTQIMKHVKDILNMTNLEAITSTYFFELTQNLEKLLKETRLKCPESLARVRPIVQHLLFIIARPARLLECIEFDPKEFYKLLEVAENNLRNV---QTDVPKYIISKLGLDKDPYDIGSEELNTSLELNGGSLEIXXXXXXXXXXXXXXXXXLNMSQESNNSLELSFSKSMTPKESDFEDIKLISNGAYGAVHLVREKKTKKRFAMKKIRKDNLLLRNQVEQIFAERDIMTFADSPFVVGLYCTFETRKYLCMIMEYVEGGDVATLIKSIGPLPDELARMYFAETVLALEYLHNFGIVHRDLKPDNLLITLEGHIKLTDFGLSKVGLMNLTTTLLESVLNKDCTMFQDKQVFGTPDYIAPEVILRQGYDKMIDWWAMGIILYEFIVGCTPFYGDSTEELFGNIISGEIEWPQDPDPCVPDNAVNLITELLKRDPLVRLGAEGTHEVKEHEFFSDVDWQGLLRQKALFIPVLDHEDDTSYFDPRTSRYQH 11214
+ RS+SL+P RS G+ E ++ +LN++YKERFP A QM +L +E+ +E + + + V Q+++ +D+L + ++TS +F+EL++ +E+LL E + K + VR +++ LL I++RPARLLEC+EF+P E+Y +LE + + + D+ Y+ ++LGLD++ +++ ++ +S + + +++ S P E DF+ IKLISNGA+GAV+LVR K+T RFA+KKI K +L +NQVEQ+FAERDI+TFA++PFVVGL+C FET+K+LCM+MEYVEGGD A+L+K+IG LP +LARMYFAETVLA+EYLH++GIVHRD+KPDNLLIT GHIKLTDFGLSK+GLMN TT + E L++D F DKQVFGTPDY+APEVILRQGY + +DWW+MGIILYEF++G PFYGD+ EELF + +SG+IE D + PD+AV+LI LL++DP RLG+ G EVKEH FF+ +DW LLRQKA FIP L+ EDDTSYFD R+ RY H
Sbjct: 75 RQRSRSLSPNRSFGSQEDELQLLNNLYKERFPNAVKQMEAKLMEFVEDYTSETWGSVFGCDGVLNFVWHQVIESARDVLLQSQESSLTSRHFYELSEKMERLLYEAKQKTEVDMTPVRRLMRKLLVIVSRPARLLECLEFNPGEYYSMLEQEGQQMNSECPEKLDITNYVKARLGLDEEGRTTEPDDITDEID------------------------------DSTDPVTPTYTTSHLPTEEDFDYIKLISNGAFGAVYLVRHKETHTRFAIKKINKHAMLHKNQVEQVFAERDILTFAENPFVVGLWCCFETKKHLCMVMEYVEGGDCASLLKNIGALPADLARMYFAETVLAVEYLHSYGIVHRDIKPDNLLITSLGHIKLTDFGLSKIGLMNSTTRMYEHSLDRDTKQFMDKQVFGTPDYLAPEVILRQGYGRAVDWWSMGIILYEFLMGVPPFYGDTPEELFAHTLSGDIE-GLDGEDAPPDDAVDLIRGLLEQDPTQRLGSAGALEVKEHVFFTGLDWTALLRQKAEFIPQLEGEDDTSYFDSRSERYNH 598
BLAST of Talin-1 vs. Ensembl Nematostella
Match: EDO28503 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T6A2]) HSP 1 Score: 413.305 bits (1061), Expect = 5.509e-130 Identity = 206/389 (52.96%), Postives = 278/389 (71.47%), Query Frame = 1
Query: 9907 VRPIVQHLLFIIARPARLLECIEFDPKEFYKLLEVAENNLRNV---QTDVPKYIISKLGLDKDPYDIGSEELNTSLELNGGSLEIXXXXXXXXXXXXXXXXXLNMSQESNNSLELSFSKSMTPKESDFEDIKLISNGAYGAVHLVREKKTKKRFAMKKIRKDNLLLRNQV-----EQIFAERDIMTFADSPFVVGLYCTFETRKYLCMIMEYVEGGDVATLIKSIGPLPDELARMYFAETVLALEYLHNFGIVHRDLKPDNLLITLEGHIKLTDFGLSKVGLMNLTTTLLESVLNKDCTMFQDKQVFGTPDYIAPEVILRQGYDKMIDWWAMGIILYEFIVGCTPFYGDSTEELFGNIISGEIEWPQDPDPCVPDNAVNLITELLKRDP 11049
VR +++ LL I++RPARLLEC+EF+P E+Y +LE + + + D+ Y+ ++LGLD++ +++ ++ +S + + +++ S P E DF+ IKLISNGA+GAV+LVR K+T RFA+KKI K +L +NQV +Q+FAERDI+TFA++PFVVGL+C FET+K+LCM+MEYVEGGD A+L+K+IG LP +LARMYFAETVLA+EYLH++GIVHRD+KPDNLLIT GHIKLTDFGLSK+GLMN TT + E L++D F DKQVFGTPDY+APEVILRQGY + +DWW+MGIILYEF++G PFYGD+ EELF + +SG+IE D + PD+AV+LI LL++DP
Sbjct: 4 VRRLMRKLLVIVSRPARLLECLEFNPGEYYSMLEQEGQQMNSECPEKLDITNYVKARLGLDEEGRTTEPDDITDEID------------------------------DSTDPVTPTYTTSHLPTEEDFDYIKLISNGAFGAVYLVRHKETHTRFAIKKINKHAMLHKNQVVISMLKQVFAERDILTFAENPFVVGLWCCFETKKHLCMVMEYVEGGDCASLLKNIGALPADLARMYFAETVLAVEYLHSYGIVHRDIKPDNLLITSLGHIKLTDFGLSKIGLMNSTTRMYEHSLDRDTKQFMDKQVFGTPDYLAPEVILRQGYGRAVDWWSMGIILYEFLMGVPPFYGDTPEELFAHTLSGDIEG-LDGEDAPPDDAVDLIRGLLEQDP 361
BLAST of Talin-1 vs. Ensembl Nematostella
Match: EDO37800 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SEW2]) HSP 1 Score: 207.608 bits (527), Expect = 6.342e-58 Identity = 119/343 (34.69%), Postives = 191/343 (55.69%), Query Frame = 1
Query: 10234 LELSFSKSMTPKESDFEDIKLISNGAYGAVHLVREKKTKKRFAMKKIRKDNLLLRNQVEQIFAERDIMT-FADSPFVVGLYCTFETRKYLCMIMEYVEGGDVATLIKSIGPLPDELARMYFAETVLALEYLHNFGIVHRDLKPDNLLITLEGHIKLTDFGLSKVGLMNLTTTLLESVLNKDCTMFQDKQVFGTPDYIAPEVILRQGYDKMIDWWAMGIILYEFIVGCTPFYGDSTEELFGNIISGEIEWPQDPDPCVPDNAVNLITELLKRDPLVRLGA-EGTHE-VKEHEFFSDVDWQGLLRQ--KALFIPVLDHEDDTSYFDPRTSRYQHESESDDPDPGS 11247
++L S + K SDF +K+I G++G V L + K+ K +A+K + K + RN+ + I AER+++ PF+VGL+ +F+T+ L +++YV GG++ ++ P+ AR Y AE A+ YLH I++RDLKP+N+L+ +GHI LTDFGL K G+ TT GTP+Y+APEV+ +Q YDK +DWW +G +LYE + G PFY T E++ NI+ + + + +A +++ LL++D RLG+ EG E ++ H FF ++WQ L+ + + + P + + D +FDP R +P PGS
Sbjct: 59 IDLGESNNPKAKPSDFLFLKVIGKGSFGKVFLSKNKQEDKFYAIKVLNKSAIRKRNEAKHIMAERNVLVQNVTHPFLVGLHYSFQTKDKLYFVLDYVNGGELFFHLQRERYFPESRARFYAAEIASAIGYLHGLQIIYRDLKPENILLDSKGHIVLTDFGLCKEGIDRSGTT---------------STFCGTPEYLAPEVLRKQDYDKSVDWWCLGAVLYEMMYGLPPFYSRDTAEMYDNILHKPLRLRTN----ISQSARHILEGLLQKDKTKRLGSGEGDFEDIRTHSFFRSINWQQLVARGIEPPYNPNVSGQLDLKHFDPEFVR--------EPVPGS 374
BLAST of Talin-1 vs. Ensembl Nematostella
Match: EDO35228 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SM62]) HSP 1 Score: 204.527 bits (519), Expect = 8.183e-58 Identity = 110/310 (35.48%), Postives = 182/310 (58.71%), Query Frame = 1
Query: 10273 SDFEDIKLISNGAYGAVHLVREKKTKKRFAMKKIRKDNLLLRNQVEQIFAERDIMTFADSPFVVGLYCTFETRKYLCMIMEYVEGGDVATLIKSIGPLPDELARMYFAETVLALEYLHNFGIVHRDLKPDNLLITLEGHIKLTDFGLSKVGLMNLTTTLLESVLNKDCTMFQDKQVFGTPDYIAPEVILRQGYDKMIDWWAMGIILYEFIVGCTPFYGDSTEELFGNIISGEIEWPQDPDPCVPDNAVNLITELLKRDPLVRLGA--EGTHEVKEHEFFSDVDWQGLLRQKAL--FIPVLDHEDDTSYFD 11190
DFE K + G +G V L R+++ + +A+K + ++ QVE + E++I+ + PF+V L T + +L M++EY GG++ T +++ G + + +E V A++YLH IV+RDLKP+N+L+ +GH+KLTDFG +K V +K T+ GTP+Y+APE+I +G++K +DWWA+GI++YE +VG PF+ D+ ++ I+SG++EWP+ D +A +LI +LL D RLG+ G+ +VK H++F +DW +L++K P + H DT FD
Sbjct: 16 QDFELSKTLGTGTFGRVLLARDRRGGEFYALKIMNISEVIRLKQVEHVQNEKNILMSIEHPFIVNLLWTQHDQTFLYMLLEYACGGELFTYLRTAGRFNNGTGLFFGSEIVSAMDYLHGHSIVYRDLKPENILLDRDGHVKLTDFGFAK------------EVHDKTWTL------CGTPEYLAPEIIQSKGHNKAVDWWALGILIYEMLVGYPPFFDDNPFGIYEKILSGKVEWPKHMDNT---SAKDLIKKLLVHDRTRRLGSMKNGSEDVKNHKWFKVIDWNLVLQRKLKPPINPKISHPGDTRNFD 304
BLAST of Talin-1 vs. Ensembl Medaka
Match: tln2a (talin-2 [Source:NCBI gene;Acc:101173776]) HSP 1 Score: 952.199 bits (2460), Expect = 0.000e+0 Identity = 698/2291 (30.47%), Postives = 1194/2291 (52.12%), Query Frame = 1
Query: 49 FELRIHIVDADVTKIVPLDPEATIFQLCETIRKNIREAQTKSPKSYGLYLPHDDLKKGLWLDNSKTLQHYILKRGDTIEYRNRSRWLHIRTMDGTNKTLKVDDSWTVSELMLTVCTKLGIYNYDEYSLISDKMDFSPGIDKTLSMKRGISINXXXXXXXXXXXXYHTEDGLNWLNPSQSLRQQGIEESEVLLLKRKYFFSDMNVDSRDPIQLSLLYEQLKDAVINGTHPVTLPEAIELAGLQCQVQLGNYSADKFKPGFLDLRECLPKEYQKNPKTVEKKIFNQHSKSKDLSEVEAKEKYCLLCRSFKTYGITFFLVKEKVIGKNKLIPRLLGVNKESVVQVDEKTKEIINTWPLTSIRKWAASFNGFTMDFGEYSPDEYYTAQTDKGERISQLIAGYIDIILKRKKAKDHLGVDADEESIMYEENIAPSKAIIVEH----VPKQKRSSVSEEDVVIRKKAHMANSSVRMNSQASDSVCSQDCTDFYQEDINMSRQTSSLGRTQSPSSSLTTNSMHY-RMSDDDIRQKLYIISLQDNLDTIQKYKDQLMIENKGPEIGKDEASQQWIYVNIDNSRQRMADEIGAMNAAVAQVLRSAQGLATIXXXXXXXXXXXXIAKMQNSFSLITVHLPSLMEEIRTAAYYQDQLTDEDVSGEELIAAAKRLADAFTNLIKAAYPVEDQKRSLNRKEIFDAANAVGEASSDLLQQITEQENCQIELKSERPYSIIMITEEDQLYQEELLRLAKSVANETTNLIKQVKVIAVEAENPSDQKKVVMAATETGLAISQLISTTKIVAPTIEQSVCQEQLIFSIEDVSKAIQVVVESSNKATQSEELQDLTVQAANQVQEALDTLMKHLRXXXXXXXXXXXXXXAYENI----QEXXXXXXXXXXXXXXXRRLAQATTAMISEIQLKAVNEQYKTPEERDKLINAAKQLAEATTVLIDSAKNCTMDKDEMNLRYTLREATERFIVVTYTTECATYIQEQVIDHL--LVAARKAATTGTHLINTSLSAAKKSRASNFKVCNDGRELSNQISNLIVAIKEARRDPKDHLAQLELIAACRDYIDPSEQLSQSNKYMWPTVSDPSLQTALNQSINQSVIATEELKKCVHQADLMCQHLDLSAALEQLKRLEQNLKSIKNSIERENLIPLPDEKSDESAALLIKSVRRSGSAANQFKNDLESRCVVYEQTNGEDSYQNLENLDVAGQKARELSMALDRLVHAARGVAASIEFENQESENNDKNLEKLAQLQIVNNCLEAVKAARDLVIEAKS---SPPDNDQMDRAQQASVRXXXXXXXXXXXXPGQRDLDMLSKHIESKKHQFAENRLPIQQNNNINLSNCRSELTDTTFDFNQAVNELVSAPSFNLVNKGCKKMRMSYDRIVEICNVLVHDPFDESDSALHHLSSNRDHIANGVMIMSE------DCQTLLDKVKKIQCEPDNIIVRKQLQEATKMLLDSINRLLTNISTNLRPGQKECDKTIYRLESMRPILDNPVHPISHKDYFECLDFIIDKTVQPLADSLKNIPAAVKDENNQKFIDSIYHCADSVCMLLEETAQTAYLVGVGDVRSKIGNKGLADHTSFLQIQKEISENCQTICNPDTTARQDSSLMISTAGQIAENSRKLCEASK--TIMISFPNDKIKLSDKTKITLLAVSELMTGVQNLNQNFNEDNRKEVESLSGKVQDNVAELVQLLLSYKFAGDAAIISEEAKESQGPIKAAGITVLDTAIEVIQCSKALISSEANEELFIAYSSSCKDLNDALKHLISTIKESAPGQKECDEXXXXXXXXXXQAYDSKMKIMKHRSRTISRTFESEESYQNILQSALIQMPHCINELSRAGKKEPEQLARIFSRQTQLLESMVNSCICAANQTDLIQNSNIYLEHLITILEASEQLLKAVKKSGGNPKANSVHSQIDEMAQGVIESCEDLLAALDKISFKQGNVNTIVETITKSSAKVQESAIIPEKSRFGNSQSKMLDICYDMNNLTTDISSNANSESTQRLLAP-----LTQNLTQRYDDLCRACQGAVA--TLSNENNGKQLQECVQTVGKVSISLVK--STTEVRPSVASSISNLQAKTQELHKRIDDVIQLLISSNVGTQACTQAIKILKEINSDIDTSILFVKSADIQNDDREYYSVKELFKKSRNSVIDNSSELVRNIKLIVSKDVCDVNILQESADQIAITSQSLANDVKVGLEHLNSSTSQYNIELLVSFQEVIVSLISFLEVARNTSGLPYTDPLFQNLKEEGKCSINAITSLLKVLKSMDDVNLKDFQAIDNAI 6828
L+I + +V K + +P I+ C IR + EAQT YGL+L +D +KG+WL++ +TL +Y+L+ GD +EY+ + R I+ +DG KT+ VDDS TV EL++T+C+++GI NY+EYSLI + ++ D T ++K+ ++ +D+ K++KLK K HT+D LNWL+ S++ R+QG++++E LLL+RK+F+SD NVDSRDP+QL+LLY Q +D ++NG+HPV+ +A E AG+Q Q+Q G++ K KPGFLDL+E LPKEY K + EKKIF +H +++E+EAK KY L RS +TYG++FFLVKEK+ KNKL+PRLLG+ KESV++VDEKTK+++ WPLT++++WAAS FT+DFGEY + YY+ QT +GE+ISQLIAGYIDIILK+K++KD G++ DEES M EE+++P K+ I++ V + + SV+ V +R S ++S+ +LG SP +T MH M Q+ + ++ ++ +QK + L + P +G+D AS+ WI +D S+ + ++ A+ A A V+ G T + I+ S L +LME D+ G +L+ AA+ LA A ++L+KA P + R+ + AA ++G+AS DLL+QI E E D+ +Q+ L+ LAK+VAN L+ + K +A AE+ Q +V+ AAT+ L+ SQL++ K+V+PTI VCQEQLI + + V ++++ +++ AT+ EL AA+ V +AL L++H+R+ + + + + A + I + + S D ++V AR LAQAT+ +++ ++ A E + KL+ AAK LA+AT ++++AK + + + LREA E V T I++++I+ L AA T T + +A+ K+ A++ ++ + +++ I L+ ++ ++ P+D AQL LI A ++++ P ++ S K PTV+D + L Q EL+ +A C +++ +AL ++ L L+ K + L PLP E ++ A L + + GS+ Q C G + + G ARE + AL L AARGVAASI + A ++++ + ++ + L+ EAK SP D + R Q + +S +L+ C++ LPGQ+D+DM K I + + +P N + ++EL T D NQ+ E+V+A R S ++ HD FDE A ++ + + V ++S LL K + +P + L A + + DSIN+L+T + T PGQKECD + LE++R +LDNP P++ YF+C++ +++ + + L +S+ I K + F DS+ + ++C L E Q +YLVGV D S+ G++GL D F + + I CQ + +P+++ Q ++S A +A+++ LC A + + + P K K + + L+ ++ L+ +F+E+NR + + + + V L + +FA A IS E +Q PI + ++LD++ +++ +++L + + + + + ++D++K LI+ I++ APGQ+ECD ++ + K I+ + + ++ SR S E+ Q L S + ++ H I+ +S A + E QL ++ E ++ + + A++ + Q +L+ T+ E++ Q+L A K+ GGNPKA+ H I E AQ + E+ +D++ L++ + + G V +VE+I ++ AK+ E ++ F + Q+ M+ + I+ A T+ + +P L +T Y L A QG +A T E G Q++ VQ +G I LV+ ++ P+ + + L + + +++ V+ L + N GTQAC A + I +D+DT+I+F + + ++ E F R +++ + LV + K++VS L ++A A T L + VK+G + S + + L+ + ++V +L + + +G DP LK K + +TSLLK +K+++D + +A++ I
Sbjct: 4 LSLKICVRQCNVVKTMQFEPSTAIYDACRIIRDRVPEAQTGQASDYGLFLSDEDPRKGIWLESGRTLDYYMLRNGDILEYKKKQRPQKIKMLDGAVKTIMVDDSKTVGELLVTICSRIGITNYEEYSLIQETVE-EKKEDGTGTLKKDRTLLRDERKMEKLKAKLHTDDDLNWLDHSRTFREQGVDDNETLLLRRKFFYSDQNVDSRDPVQLNLLYVQARDDILNGSHPVSFDKACEFAGIQAQIQFGSHIEHKHKPGFLDLKEFLPKEYIKQ-RGAEKKIFQEHKNCGEMTEIEAKVKYVKLARSLRTYGVSFFLVKEKMKSKNKLVPRLLGITKESVMRVDEKTKDVVQEWPLTTVKRWAASPKSFTLDFGEYQ-ESYYSVQTTEGEQISQLIAGYIDIILKKKQSKDRFGLEGDEESTMLEESVSPKKSTILQQQFNRVGRVEHGSVALPGV------------IRSGSIGTESL--------------------TLGTMPSPQQQITMGQMHRGHMPPLSSAQQALMGTINTSMQAVQKAQIDLGEVDNLPPLGQDMASKVWIQNKMDESKHEIHSQVDAITAGTASVVNLTAGDPTDTDYTAVGCAITTISSNLTEMSKGVKLLAALME-------------DDVGGGNDLMKAARTLAGAVSDLLKAVEPASGEP----RQTVLTAAGSIGQASGDLLRQIGENET-------------------DERFQDVLMNLAKAVANAAAMLVLKAKNVAQVAEDTVLQNRVIAAATQCALSTSQLVACAKVVSPTISSPVCQEQLIEAGKLVDRSVESCIQACLSATEDGELLKQVSAAASVVSQALADLLQHVRQYTSRGEPIGRYDQATDTIMTVTESIFISMGDAGEMVRQARVLAQATSDLVNAMRSDA--EAEVDVDNSKKLLAAAKLLADATARMVEAAKGAAAYPENEDQQQRLREAAEGLRVAT-NAAAQNAIKKKLINRLENAAKQAAAAATQTIAAAQNAAASNKNTAAHQQLVQSCKAVADHIPQLVQGVRSSQAKPEDLSAQLALIIASQNFLQPGSKMVTSAKSSVPTVTDQAAAMQLGQCAKNLATCLAELRTAAQKAHEACGPMEIDSALTAIQTLRSELQDAKLAATTTQLKPLPGESLEKCAQDLGSTSKSVGSSMAQLLT-----CAA----QGNEHF--------TGIAARETAQALKTLAQAARGVAASI-------------TDPKASAAMLDSARDVMEGSALLIHEAKQALISPADAESQQRLAQVAKAVSHSLNNCVNCLPGQKDVDMALKSIGEASKKLLMDAIP---PANKSFQEAQNELNQTAADLNQSAGEVVTA------------TRGSSSQLAVASGKFSHD-FDEFLDAGIEMAGHTQKKDDQVQVISNLKNISMASSKLLLAAKSLSVDPAAANAKNLLAAAARAVTDSINQLIT-LCTQQAPGQKECDNALRELEAVRGMLDNPSEPVNDLSYFDCIESVMENS-KVLGESMAGISQNCKISDVTAFGDSVGSASKALCGLTEAAGQASYLVGVSDPNSQAGHQGLVDPIQFAKANQAIQMACQNLVDPESSPSQ----VLSAATIVAKHTSALCNACRLASSKTTNPVAKRHFVQSAKEVANSTANLVKTIKALDGDFSEENRSRCQVATTPLIEAVENLTTFASNPEFASVPAQISNEGSAAQEPIIQSARSMLDSSTLLLKTARSLALNPKDPPTWSVLAGHSRTVSDSIKSLITAIRDKAPGQRECDSSIDNINKCIRDIEQASLAVVSQ--NLPSRDDISLEALQEQLTSTVQEIGHLIDPVSTAARGEASQLGHKVTQLAGYFEPLIKASVGVASKLNDHQQQMTFLDQTKTLAESALQMLYAAKEGGGNPKASHTHDAIAEAAQLMKEAVDDIMVTLNEAASEVGMVGGMVESIAEAMAKLDEGTPPEDEGSFVDYQTSMV-------KHSKAIAVTAQEMMTKSVTSPDELGALASQVTVDYSQL--AVQGRLASHTAEPEEIGFQIKTRVQELGHGCIYLVQKAGALQISPTDSFTKRELIECARAVTEKVSLVLSALQAGNKGTQACITAASAVSGIIADLDTTIMFASAGTLNAENDES------FADHRENILKTAKALVEDTKMLVSGAASGQERLAQAAQSSAKTITQLTDVVKLGAASIGSDDPETQVVLINAVKDVAKALAELISATKCAAGKAADDPSMYQLKSAAKVMVTNVTSLLKTVKAVEDEATRGTRALEATI 2151
BLAST of Talin-1 vs. Ensembl Medaka
Match: tln2a (talin-2 [Source:NCBI gene;Acc:101173776]) HSP 1 Score: 951.429 bits (2458), Expect = 0.000e+0 Identity = 698/2291 (30.47%), Postives = 1194/2291 (52.12%), Query Frame = 1
Query: 49 FELRIHIVDADVTKIVPLDPEATIFQLCETIRKNIREAQTKSPKSYGLYLPHDDLKKGLWLDNSKTLQHYILKRGDTIEYRNRSRWLHIRTMDGTNKTLKVDDSWTVSELMLTVCTKLGIYNYDEYSLISDKMDFSPGIDKTLSMKRGISINXXXXXXXXXXXXYHTEDGLNWLNPSQSLRQQGIEESEVLLLKRKYFFSDMNVDSRDPIQLSLLYEQLKDAVINGTHPVTLPEAIELAGLQCQVQLGNYSADKFKPGFLDLRECLPKEYQKNPKTVEKKIFNQHSKSKDLSEVEAKEKYCLLCRSFKTYGITFFLVKEKVIGKNKLIPRLLGVNKESVVQVDEKTKEIINTWPLTSIRKWAASFNGFTMDFGEYSPDEYYTAQTDKGERISQLIAGYIDIILKRKKAKDHLGVDADEESIMYEENIAPSKAIIVEH----VPKQKRSSVSEEDVVIRKKAHMANSSVRMNSQASDSVCSQDCTDFYQEDINMSRQTSSLGRTQSPSSSLTTNSMHY-RMSDDDIRQKLYIISLQDNLDTIQKYKDQLMIENKGPEIGKDEASQQWIYVNIDNSRQRMADEIGAMNAAVAQVLRSAQGLATIXXXXXXXXXXXXIAKMQNSFSLITVHLPSLMEEIRTAAYYQDQLTDEDVSGEELIAAAKRLADAFTNLIKAAYPVEDQKRSLNRKEIFDAANAVGEASSDLLQQITEQENCQIELKSERPYSIIMITEEDQLYQEELLRLAKSVANETTNLIKQVKVIAVEAENPSDQKKVVMAATETGLAISQLISTTKIVAPTIEQSVCQEQLIFSIEDVSKAIQVVVESSNKATQSEELQDLTVQAANQVQEALDTLMKHLRXXXXXXXXXXXXXXAYENI----QEXXXXXXXXXXXXXXXRRLAQATTAMISEIQLKAVNEQYKTPEERDKLINAAKQLAEATTVLIDSAKNCTMDKDEMNLRYTLREATERFIVVTYTTECATYIQEQVIDHL--LVAARKAATTGTHLINTSLSAAKKSRASNFKVCNDGRELSNQISNLIVAIKEARRDPKDHLAQLELIAACRDYIDPSEQLSQSNKYMWPTVSDPSLQTALNQSINQSVIATEELKKCVHQADLMCQHLDLSAALEQLKRLEQNLKSIKNSIERENLIPLPDEKSDESAALLIKSVRRSGSAANQFKNDLESRCVVYEQTNGEDSYQNLENLDVAGQKARELSMALDRLVHAARGVAASIEFENQESENNDKNLEKLAQLQIVNNCLEAVKAARDLVIEAKS---SPPDNDQMDRAQQASVRXXXXXXXXXXXXPGQRDLDMLSKHIESKKHQFAENRLPIQQNNNINLSNCRSELTDTTFDFNQAVNELVSAPSFNLVNKGCKKMRMSYDRIVEICNVLVHDPFDESDSALHHLSSNRDHIANGVMIMSE------DCQTLLDKVKKIQCEPDNIIVRKQLQEATKMLLDSINRLLTNISTNLRPGQKECDKTIYRLESMRPILDNPVHPISHKDYFECLDFIIDKTVQPLADSLKNIPAAVKDENNQKFIDSIYHCADSVCMLLEETAQTAYLVGVGDVRSKIGNKGLADHTSFLQIQKEISENCQTICNPDTTARQDSSLMISTAGQIAENSRKLCEASK--TIMISFPNDKIKLSDKTKITLLAVSELMTGVQNLNQNFNEDNRKEVESLSGKVQDNVAELVQLLLSYKFAGDAAIISEEAKESQGPIKAAGITVLDTAIEVIQCSKALISSEANEELFIAYSSSCKDLNDALKHLISTIKESAPGQKECDEXXXXXXXXXXQAYDSKMKIMKHRSRTISRTFESEESYQNILQSALIQMPHCINELSRAGKKEPEQLARIFSRQTQLLESMVNSCICAANQTDLIQNSNIYLEHLITILEASEQLLKAVKKSGGNPKANSVHSQIDEMAQGVIESCEDLLAALDKISFKQGNVNTIVETITKSSAKVQESAIIPEKSRFGNSQSKMLDICYDMNNLTTDISSNANSESTQRLLAP-----LTQNLTQRYDDLCRACQGAVA--TLSNENNGKQLQECVQTVGKVSISLVK--STTEVRPSVASSISNLQAKTQELHKRIDDVIQLLISSNVGTQACTQAIKILKEINSDIDTSILFVKSADIQNDDREYYSVKELFKKSRNSVIDNSSELVRNIKLIVSKDVCDVNILQESADQIAITSQSLANDVKVGLEHLNSSTSQYNIELLVSFQEVIVSLISFLEVARNTSGLPYTDPLFQNLKEEGKCSINAITSLLKVLKSMDDVNLKDFQAIDNAI 6828
L+I + +V K + +P I+ C IR + EAQT YGL+L +D +KG+WL++ +TL +Y+L+ GD +EY+ + R I+ +DG KT+ VDDS TV EL++T+C+++GI NY+EYSLI + ++ D T ++K+ ++ +D+ K++KLK K HT+D LNWL+ S++ R+QG++++E LLL+RK+F+SD NVDSRDP+QL+LLY Q +D ++NG+HPV+ +A E AG+Q Q+Q G++ K KPGFLDL+E LPKEY K + EKKIF +H +++E+EAK KY L RS +TYG++FFLVKEK+ KNKL+PRLLG+ KESV++VDEKTK+++ WPLT++++WAAS FT+DFGEY + YY+ QT +GE+ISQLIAGYIDIILK+K++KD G++ DEES M EE+++P K+ I++ V + + SV+ V +R S ++S+ +LG SP +T MH M Q+ + ++ ++ +QK + L + P +G+D AS+ WI +D S+ + ++ A+ A A V+ G T + I+ S L +LME D+ G +L+ AA+ LA A ++L+KA P + R+ + AA ++G+AS DLL+QI E E D+ +Q+ L+ LAK+VAN L+ + K +A AE+ Q +V+ AAT+ L+ SQL++ K+V+PTI VCQEQLI + + V ++++ +++ AT+ EL AA+ V +AL L++H+R+ + + + + A + I + + S D ++V AR LAQAT+ +++ ++ A E + KL+ AAK LA+AT ++++AK + + + LREA E V T I++++I+ L AA T T + +A+ K+ A++ ++ + +++ I L+ ++ ++ P+D AQL LI A ++++ P ++ S K PTV+D + L Q EL+ +A C +++ +AL ++ L L+ K + L PLP E ++ A L + + GS+ Q C G + + G ARE + AL L AARGVAASI + A ++++ + ++ + L+ EAK SP D + R Q + +S +L+ C++ LPGQ+D+DM K I + + +P N + ++EL T D NQ+ E+V+A R S ++ HD FDE A ++ + + V ++S LL K + +P + L A + + DSIN+L+T + T PGQKECD + LE++R +LDNP P++ YF+C++ +++ + + L +S+ I K + F DS+ + ++C L E Q +YLVGV D S+ G++GL D F + + I CQ + +P+++ Q ++S A +A+++ LC A + + + P K K + + L+ ++ L+ +F+E+NR + + + + V L + +FA A IS E +Q PI + ++LD++ +++ +++L + + + + + ++D++K LI+ I++ APGQ+ECD ++ + K I+ + + ++ SR S E+ Q L S + ++ H I+ +S A + E QL ++ E ++ + + A++ + Q +L+ T+ E++ Q+L A K+ GGNPKA+ H I E AQ + E+ +D++ L++ + + G V +VE+I ++ AK+ E ++ F + Q+ M+ + I+ A T+ + +P L +T Y L A QG +A T E G Q++ VQ +G I LV+ ++ P+ + + L + + +++ V+ L + N GTQAC A + I +D+DT+I+F + + ++ E F R +++ + LV + K++VS L ++A A T L + VK+G + S + + L+ + ++V +L + + +G DP LK K + +TSLLK +K+++D + +A++ I
Sbjct: 4 LSLKICVRQCNVVKTMQFEPSTAIYDACRIIRDRVPEAQTGQASDYGLFLSDEDPRKGIWLESGRTLDYYMLRNGDILEYKKKQRPQKIKMLDGAVKTIMVDDSKTVGELLVTICSRIGITNYEEYSLIQETVE-EKKEDGTGTLKKDRTLLRDERKMEKLKAKLHTDDDLNWLDHSRTFREQGVDDNETLLLRRKFFYSDQNVDSRDPVQLNLLYVQARDDILNGSHPVSFDKACEFAGIQAQIQFGSHIEHKHKPGFLDLKEFLPKEYIKQ-RGAEKKIFQEHKNCGEMTEIEAKVKYVKLARSLRTYGVSFFLVKEKMKSKNKLVPRLLGITKESVMRVDEKTKDVVQEWPLTTVKRWAASPKSFTLDFGEYQ-ESYYSVQTTEGEQISQLIAGYIDIILKKKQSKDRFGLEGDEESTMLEESVSPKKSTILQQQFNRVGRVEHGSVALPGV------------IRSGSIGTESL--------------------TLGTMPSPQQQITMGQMHRGHMPPLSSAQQALMGTINTSMQAVQKAQIDLGEVDNLPPLGQDMASKVWIQNKMDESKHEIHSQVDAITAGTASVVNLTAGDPTDTDYTAVGCAITTISSNLTEMSKGVKLLAALME-------------DDVGGGNDLMKAARTLAGAVSDLLKAVEPASGEP----RQTVLTAAGSIGQASGDLLRQIGENET-------------------DERFQDVLMNLAKAVANAAAMLVLKAKNVAQVAEDTVLQNRVIAAATQCALSTSQLVACAKVVSPTISSPVCQEQLIEAGKLVDRSVESCIQACLSATEDGELLKQVSAAASVVSQALADLLQHVRQYTSRGEPIGRYDQATDTIMTVTESIFISMGDAGEMVRQARVLAQATSDLVNAMRSDA--EAEVDVDNSKKLLAAAKLLADATARMVEAAKGAAAYPENEDQQQRLREAAEGLRVAT-NAAAQNAIKKKLINRLENAAKQAAAAATQTIAAAQNAAASNKNTAAHQQLVQSCKAVADHIPQLVQGVRSSQAKPEDLSAQLALIIASQNFLQPGSKMVTSAKSSVPTVTDQAAAMQLGQCAKNLATCLAELRTAAQKAHEACGPMEIDSALTAIQTLRSELQDAKLAATTTQLKPLPGESLEKCAQDLGSTSKSVGSSMAQLLT-----CAA----QGNEHF--------TGIAARETAQALKTLAQAARGVAASI-------------TDPKASAAMLDSARDVMEGSALLIHEAKQALISPADAESQQRLAQVAKAVSHSLNNCVNCLPGQKDVDMALKSIGEASKKLLMDAIP---PANKSFQEAQNELNQTAADLNQSAGEVVTA------------TRGSSSQLAVASGKFSHD-FDEFLDAGIEMAGHTQKKDDQVQVISNLKNISMASSKLLLAAKSLSVDPAAANAKNLLAAAARAVTDSINQLIT-LCTQQAPGQKECDNALRELEAVRGMLDNPSEPVNDLSYFDCIESVMENS-KVLGESMAGISQNCKISDVTAFGDSVGSASKALCGLTEAAGQASYLVGVSDPNSQAGHQGLVDPIQFAKANQAIQMACQNLVDPESSPSQ----VLSAATIVAKHTSALCNACRLASSKTTNPVAKRHFVQSAKEVANSTANLVKTIKALDGDFSEENRSRCQVATTPLIEAVENLTTFASNPEFASVPAQISNEGSAAQEPIIQSARSMLDSSTLLLKTARSLALNPKDPPTWSVLAGHSRTVSDSIKSLITAIRDKAPGQRECDSSIDNINKCIRDIEQASLAVVSQ--NLPSRDDISLEALQEQLTSTVQEIGHLIDPVSTAARGEASQLGHKVTQLAGYFEPLIKASVGVASKLNDHQQQMTFLDQTKTLAESALQMLYAAKEGGGNPKASHTHDAIAEAAQLMKEAVDDIMVTLNEAASEVGMVGGMVESIAEAMAKLDEGTPPEDEGSFVDYQTSMV-------KHSKAIAVTAQEMMTKSVTSPDELGALASQVTVDYSQL--AVQGRLASHTAEPEEIGFQIKTRVQELGHGCIYLVQKAGALQISPTDSFTKRELIECARAVTEKVSLVLSALQAGNKGTQACITAASAVSGIIADLDTTIMFASAGTLNAENDES------FADHRENILKTAKALVEDTKMLVSGAASGQERLAQAAQSSAKTITQLTDVVKLGAASIGSDDPETQVVLINAVKDVAKALAELISATKCAAGKAADDPSMYQLKSAAKVMVTNVTSLLKTVKAVEDEATRGTRALEATI 2151
BLAST of Talin-1 vs. Ensembl Medaka
Match: tln1 (talin 1 [Source:NCBI gene;Acc:101157630]) HSP 1 Score: 947.192 bits (2447), Expect = 0.000e+0 Identity = 697/2279 (30.58%), Postives = 1180/2279 (51.78%), Query Frame = 1
Query: 55 LRIHIVDADVTKIVPLDPEATIFQLCETIRKNIREAQTKSPKSYGLYLPHDDLKKGLWLDNSKTLQHYILKRGDTIEYRNRSRWLHIRTMDGTNKTLKVDDSWTVSELMLTVCTKLGIYNYDEYSLISDKMDFSPGIDKTLSMKRGISINXXXXXXXXXXXXYHTEDGLNWLNPSQSLRQQGIEESEVLLLKRKYFFSDMNVDSRDPIQLSLLYEQLKDAVINGTHPVTLPEAIELAGLQCQVQLGNYSADKFKPGFLDLRECLPKEYQKNPKTVEKKIFNQHSKSKDLSEVEAKEKYCLLCRSFKTYGITFFLVKEKVIGKNKLIPRLLGVNKESVVQVDEKTKEIINTWPLTSIRKWAASFNGFTMDFGEYSPDEYYTAQTDKGERISQLIAGYIDIILKRKKAKDHLGVDADEESIMYEENIAPSKAIIVEH----VPKQKRSSVSEEDVVIRKKAHMANSSVRMNSQASDSVCSQDCTDFYQEDINMSRQTSSLGRTQSPSSSLTTNSMHY-RMSDDDIRQKLYIISLQDNLDTIQKYKDQLMIENKGPEIGKDEASQQWIYVNIDNSRQRMADEIGAMNAAVAQVLRSAQGLATIXXXXXXXXXXXXIAKMQNSFSLITVHLPSLMEEIRTAAYYQDQLTDEDVSGEELIAAAKRLADAFTNLIKAAYPVEDQKRSLNRKEIFDAANAVGEASSDLLQQITEQENCQIELKSERPYSIIMITEEDQLYQEELLRLAKSVANETTNLIKQVKVIAVEAENPSDQKKVVMAATETGLAISQLISTTKIVAPTIEQSVCQEQLIFSIEDVSKAIQVVVESSNKATQSEELQDLTVQAANQVQEALDTLMKHLRXXXXXXXXXXXXXXAYENI----QEXXXXXXXXXXXXXXXRRLAQATTAMISEIQLKAVNEQYKTPEERDKLINAAKQLAEATTVLIDSAKNCTMDKDEMNLRYTLREATERFIVVTYTTECATYIQEQVIDHLLVAARKAATTGTHLINTSLSAAK--KSRASNFKVCNDGRELSNQISNLIVAIKEARRDPKDHLAQLELIAACRDYIDPSEQLSQSNKYMWPTVSDPSLQTALNQSINQSVIATEELKKCVHQADLMCQHLDLSAALEQLKRLEQNLKSIKNSIERENLIPLPDEKSDESAALLIKSVRRSGSAANQFKNDLESRCVVYEQTNGEDSYQNLENLDVAGQKARELSMALDRLVHAARGVAASIEFENQESENNDKNLEKLAQLQIVNNCLEAVKAARDLVIEAK---SSPPDNDQMDRAQQASVRXXXXXXXXXXXXPGQRDLDMLSKHIESKKHQFAENRLPIQQNNNINLSNCRSELTDTTFDFNQAVNELVSAPSFNL--VNKGCKKMRMSYDRIVEICNVLVHDPFDESDSALHHLSSNRDHIANGVMIMSEDCQTLLDKVKKIQCEPDNIIVRKQLQEATKMLLDSINRLLTNISTNLRPGQKECDKTIYRLESMRPILDNPVHPISHKDYFECLDFIIDKTVQPLADSLKNIPAAVKDENNQKFIDSIYHCADSVCMLLEETAQTAYLVGVGDVRSKIGNKGLADHTSFLQIQKEISENCQTICNPDTTARQDSSLMISTAGQIAENSRKLCEASKTIMISFPN--DKIKLSDKTKITLLAVSELMTGVQNLNQNFNEDNRKEVESLSGKVQDNVAELVQLLLSYKFAGDAAIISEEAKESQGPIKAAGITVLDTAIEVIQCSKALISSEANEELFIAYSSSCKDLNDALKHLISTIKESAPGQKECDEXXXXXXXXXXQAYDSKM-KIMKHRSRTISRTFESEESYQNILQSALIQMPHCINELSRAGKKEPEQLARIFSRQTQLLESMVNSCICAANQTDLIQNSNIYLEHLITILEASEQLLKAVKKSGGNPKANSVHSQIDEMAQGVIESCEDLLAALDKISFKQGNVNTIVETITKSSAKVQESAIIPEKSRFGNSQSKMLDICYDMNNLTTDISSNANSESTQRLLAPLTQNLTQRYDDLCRACQGAVATLSNENNGKQLQECVQTVGKVSISLVKSTTEVR--PSVASSISNLQAKTQELHKRIDDVIQLLISSNVGTQACTQAIKILKEINSDIDTSILFVKSADIQNDDREYYSVKELFKKSRNSVIDNSSELVRNIKLIVSKDVCDVNILQESADQIAITSQSLANDVKVGLEHLNSSTSQYNIELLVSFQEVIVSLISFLEVARNTSGLPYTDPLFQNLKEEGKCSINAITSLLKVLKSMDDVNLKDFQAIDNAI 6828
L + I +V K + +P ++ C IR+ + EAQ P YGL+L +D KKG+WL+ K L +Y+L+ GDT++Y+ + R L IR +DGT KT+ VDDS VS++++T+C ++GI NYDEYSL+ D + + T ++K+ ++ +D +K++KLK+K HT+D LNWL+ ++LR+QG+EE+E+LLL+RK+F+SD NVDSRDP+QL+LLY Q +D ++NG+HPV+ +A E AG QCQ+Q G+++ K K GFLDL+E LPKEY KN EKKIF H ++++E+EAK Y L RS KTYG++FFLVKEK+ GKNKL+PRLLG+ KE V++VDEKTKE+I W LT+I++WAAS FT+DFG+Y D YY+ QT +GE+I+QLIAGYIDIILK+KK+KDH G++ DEES M E++++P K+ +++ + K + SV+ ++R A S +Q +G +T+ MH M Q+ ++ ++ +Q + L + P +G D ASQ W +D S+ + ++ A+ A A ++ G + I+ S L +LME DE +G+ L+ AAK LA A ++++K A P + R + + AA VG+ S +LL I E T+ D +QE L++LAK+VAN L+ + K +A + E+ + Q +V+ AAT+ L+ SQL++ T++VAPTI VCQEQLI + + V+K+++ V +S AT E L AA V + L+ L++H+++ + A + I + + S D ++V AR LAQAT+ +++ I++ A E E KL++AAK LA+AT ++++AK + D + LREA E + T I++++++ L AA++AA T I + AA K++ + ++ + ++ QI L+ ++ ++ P AQL LI A ++++ P ++ + K PT+SD + L+Q A EL+ +A C L++ AL ++ LE++++ K S L PLP E + + L + + SA Q + E T G+++Y AG AR+++ L LV AARGVAAS D + A L + L+ K+A +L+ EAK + P D + R Q + +S AL+ C++ LPGQRD+D + + + P ++ + +++L + NQ+ NE+V A + K K + ++ + + D + + + + +S LL K + + + ++ QL A + + DSIN+L+T + T PGQKECD + LES++ +L+NP ++ +FEC+D +++ + + L +S+ I K+ N +F DS+ + ++C L E AQ AYLVGV D S G KGL D T F + + I CQ + +P T Q ++S A +A+++ LC A + N K + K + L+ ++ L+ F+++NR++ ++ +G + + V L + +FA A IS E + PI AA T+L+++ +IQ +++L + + + + + ++D++K LI+ ++E APGQ+ECD+A+ +L I++ + + I +H + R S E+ + +++ ++ + I+ ++ A + E QL S+ E ++ + I A++ Q L+ T+ E++ Q+L K++GGNPKA + ++E Q + E+ +DL A L + G V +V+TI + K+++S + F + Q+ M+ + ++ + +N+ L L LT + +L + A T N+ G +++ V +G LV ++ P+ + L +++ +++ V+ L + N GTQAC A + I +D+DT+I+F + + ++ E F R ++ + LV + KL+VS L ++A T LA VK+G L S + + L+ + ++V +L + + + +G P+ DP LK K + +TSLLK +K+++D K +A++ I
Sbjct: 4 LSLKIGVGNVVKTMQFEPSTMVYDACRIIRERVPEAQLGQPNDYGLFLSDEDPKKGIWLEAGKALDYYMLRNGDTLDYKKKQRPLKIRMLDGTVKTVMVDDSKIVSDMLMTICARIGITNYDEYSLVHD-IGEEKKEETTGTLKKDKTLLRDDKKMEKLKQKLHTDDELNWLDHGRTLREQGVEETEMLLLRRKFFYSDQNVDSRDPVQLNLLYVQARDDILNGSHPVSFDKACEFAGYQCQIQFGDHNESKHKSGFLDLKEFLPKEYIKNKG--EKKIFQAHKNCQNMTEIEAKVSYVKLARSLKTYGVSFFLVKEKMKGKNKLVPRLLGITKECVMRVDEKTKEVIQEWNLTNIKRWAASPKSFTLDFGDYQ-DGYYSVQTTEGEQIAQLIAGYIDIILKKKKSKDHFGMEGDEESTMLEDSVSPKKSTVLQQQFNKMGKVETGSVALP-AIMRSGAGGPES--------------------FQ-----------MGSMPQAKQHITSGQMHRGHMPPLTSAQQALTGTINSSMQAVQAAQASLEDFDTLPPLGTDAASQAWRKNKMDESKHEIHSQVDAITAGTASMVNLTAGDPAETDYTAVGCAVTTISSNLTEMSKGVKLLAALME-------------DEGGNGQLLLGAAKNLACAVSDMLKTAQPANTEPR----QNLLQAAGNVGQTSGELLSHIGE-------------------TDTDPQFQEMLMQLAKAVANAAAALVLKAKNVAQKTEDSAQQNRVIAAATQCALSTSQLVACTRVVAPTISSPVCQEQLIEASKLVAKSVEGCVGASQSATNDEGLLKQVGVAATGVTQTLNELLQHIKQYASGGHPIGRHGEATDRILNVTENIFSSMGDAGEMVRQARILAQATSDLVNAIKMDAEGE--SDLENSRKLLSAAKLLADATAKMVEAAKGAAANPDSEEQQQKLREAAEGLRMAT-NAAAQNAIKKRLVNKLENAAKQAAAAATQTIAAAQHAASTNKNQGAQQQLVQSCKVVAEQIPQLVQGVRGSQSQPDSPSAQLALINASQNFLQPGAKMVTAAKATVPTISDQASAMQLSQCAKNLASALAELRTASQKAQDACGQLEIDNALVMVRDLEKDIQEAKASAREGKLKPLPGETLGKCSQDLSTNTKAVTSAIAQL---------LSEATQGDENY--------AGISARDMAQTLKSLVSAARGVAAS----------TDDPAARGAVLDCAGDVLD--KSA-NLIEEAKRAIAKPGDAESQQRLAQVAKAMSQALNRCVNCLPGQRDVDNAIRTVGEASKTLLADSFP---SSGKSFQELQAQLNEVAAGLNQSANEVVQASRGTTQDLAKATSKFGQDFSNFLDAGVDMAGTSQSKED---------QTQVVSNLKTISMSSSKLLLAAKALSTDSSSPNLKNQLAAAARAVTDSINQLIT-MCTQQAPGQKECDNALRELESVKGMLENPTEAVNDLSFFECIDSVMENS-KVLGESMAGISHNAKNSNLPEFGDSVSAASKALCGLTEGAAQAAYLVGVSDPNSTAGQKGLVDPTQFARANQSIQMACQNLVDPACTQSQ----VLSAATIVAKHTSALCNACRLASSQTSNAVAKRQFVQSAKEVANTTANLVKSIKALDGAFSQENREKCKAATGPLIEAVDNLTAFASNPEFASIPAHISPEGHAAMEPIVAAAQTMLESSTGLIQTARSLAVNPKDPPTWSVLAGHSRTVSDSIKKLITNMREKAPGQRECDDAIEVLNGCIREVDQASLAAISQHLT---PREDISMETLHEQMAASVHEISNLIDPVAVAARSEASQLGHKVSQMASYFEPLIMAAIGTASKILSSQQQMAVLDQTKTLAESALQMLYTAKEAGGNPKAAHMQEAVEESVQMMKEAVDDLGATLADAASAAGAVGGMVDTINDAINKMEDSHTLDHDGTFVDYQTTMVKTAKAIAVTVQEMVTKSNTNPDD--LGGLANQLTNNFGNLANEAKYAALTAENDEIGSHIKKQVGELGFTCTGLVTKAGALQCSPNDTFTKKELIESARKVSEKVSHVLASLQAGNRGTQACITAASAVSGIIADLDTTIMFATAGTLHREN------AETFADHRECILKTAKALVEDTKLLVSGAGASQEKLAQAAQSSVSTITKLAEVVKLGAASLGSEDPETQVVLINAVKDVAKALSNLISATKAAAGKPHDDPSMLQLKNSAKVMVTNVTSLLKTVKAVEDEATKGTRALEATI 2148
BLAST of Talin-1 vs. Ensembl Medaka
Match: tln2a (talin-2 [Source:NCBI gene;Acc:101173776]) HSP 1 Score: 874.774 bits (2259), Expect = 0.000e+0 Identity = 666/2200 (30.27%), Postives = 1141/2200 (51.86%), Query Frame = 1
Query: 322 MDGTNKTLKVDDSWTVSELMLTVCTKLGIYNYDEYSLISDKMDFSPGIDKTLSMKRGISINXXXXXXXXXXXXYHTEDGLNWLNPSQSLRQQGIEESEVLLLKRKYFFSDMNVDSRDPIQLSLLYEQLKDAVINGTHPVTLPEAIELAGLQCQVQLGNYSADKFKPGFLDLRECLPKEYQKNPKTVEKKIFNQHSKSKDLSEVEAKEKYCLLCRSFKTYGITFFLVKEKVIGKNKLIPRLLGVNKESVVQVDEKTKEIINTWPLTSIRKWAASFNGFTMDFGEYSPDEYYTAQTDKGERISQLIAGYIDIILKRKKAKDHLGVDADEESIMYEENIAPSKAIIVEH----VPKQKRSSVSEEDVVIRKKAHMANSSVRMNSQASDSVCSQDCTDFYQEDINMSRQTSSLGRTQSPSSSLTTNSMHY-RMSDDDIRQKLYIISLQDNLDTIQKYKDQLMIENKGPEIGKDEASQQWIYVNIDNSRQRMADEIGAMNAAVAQVLRSAQGLATIXXXXXXXXXXXXIAKMQNSFSLITVHLPSLMEEIRTAAYYQDQLTDEDVSGEELIAAAKRLADAFTNLIKAAYPVEDQKRSLNRKEIFDAANAVGEASSDLLQQITEQENCQIELKSERPYSIIMITEEDQLYQEELLRLAKSVANETTNLIKQVKVIAVEAENPSDQKKVVMAATETGLAISQLISTTKIVAPTIEQSVCQEQLIFSIEDVSKAIQVVVESSNKATQSEELQDLTVQAANQVQEALDTLMKHLRXXXXXXXXXXXXXXAYENI----QEXXXXXXXXXXXXXXXRRLAQATTAMISEIQLKAVNEQYKTPEERDKLINAAKQLAEATTVLIDSAKNCTMDKDEMNLRYTLREATERFIVVTYTTECATYIQEQVIDHL--LVAARKAATTGTHLINTSLSAAKKSRASNFKVCNDGRELSNQISNLIVAIKEARRDPKDHLAQLELIAACRDYIDPSEQLSQSNKYMWPTVSDPSLQTALNQSINQSVIATEELKKCVHQADLMCQHLDLSAALEQLKRLEQNLKSIKNSIERENLIPLPDEKSDESAALLIKSVRRSGSAANQFKNDLESRCVVYEQTNGEDSYQNLENLDVAGQKARELSMALDRLVHAARGVAASIEFENQESENNDKNLEKLAQLQIVNNCLEAVKAARDLVIEAKS---SPPDNDQMDRAQQASVRXXXXXXXXXXXXPGQRDLDMLSKHIESKKHQFAENRLPIQQNNNINLSNCRSELTDTTFDFNQAVNELVSAPSFNLVNKGCKKMRMSYDRIVEICNVLVHDPFDESDSALHHLSSNRDHIANGVMIMSE------DCQTLLDKVKKIQCEPDNIIVRKQLQEATKMLLDSINRLLTNISTNLRPGQKECDKTIYRLESMRPILDNPVHPISHKDYFECLDFIIDKTVQPLADSLKNIPAAVKDENNQKFIDSIYHCADSVCMLLEETAQTAYLVGVGDVRSKIGNKGLADHTSFLQIQKEISENCQTICNPDTTARQDSSLMISTAGQIAENSRKLCEASK--TIMISFPNDKIKLSDKTKITLLAVSELMTGVQNLNQNFNEDNRKEVESLSGKVQDNVAELVQLLLSYKFAGDAAIISEEAKESQGPIKAAGITVLDTAIEVIQCSKALISSEANEELFIAYSSSCKDLNDALKHLISTIKESAPGQKECDEXXXXXXXXXXQAYDSKMKIMKHRSRTISRTFESEESYQNILQSALIQMPHCINELSRAGKKEPEQLARIFSRQTQLLESMVNSCICAANQTDLIQNSNIYLEHLITILEASEQLLKAVKKSGGNPKANSVHSQIDEMAQGVIESCEDLLAALDKISFKQGNVNTIVETITKSSAKVQESAIIPEKSRFGNSQSKMLDICYDMNNLTTDISSNANSESTQRLLAP-----LTQNLTQRYDDLCRACQGAVA--TLSNENNGKQLQECVQTVGKVSISLVK--STTEVRPSVASSISNLQAKTQELHKRIDDVIQLLISSNVGTQACTQAIKILKEINSDIDTSILFVKSADIQNDDREYYSVKELFKKSRNSVIDNSSELVRNIKLIVSKDVCDVNILQESADQIAITSQSLANDVKVGLEHLNSSTSQYNIELLVSFQEVIVSLISFLEVARNTSGLPYTDPLFQNLKEEGKCSINAITSLLKVLKSMDDVNLKDFQAIDNAI 6828
+DG KT+ VDDS TV EL++T+C+++GI NY+EYSLI + ++ D T ++K+ ++ +D+ K++KLK K HT+D LNWL+ S++ R+QG++++E LLL+RK+F+SD NVDSRDP+QL+LLY Q +D ++NG+HPV+ +A E AG+Q Q+Q G++ K KPGFLDL+E LPKEY K + EKKIF +H +++E+EAK KY L RS +TYG++FFLVKEK+ KNKL+PRLLG+ KESV++VDEKTK+++ WPLT++++WAAS FT+DFGEY + YY+ QT +GE+ISQLIAGYIDIILK+K++KD G++ DEES M EE+++P K+ I++ V + + SV+ V +R S ++S+ +LG SP +T MH M Q+ + ++ ++ +QK + L + P +G+D AS+ WI +D S+ + ++ A+ A A V+ G T + I+ S L +LME D+ G +L+ AA+ LA A ++L+KA P + R+ + AA ++G+AS DLL+QI E E D+ +Q+ L+ LAK+VAN L+ + K +A AE+ Q +V+ AAT+ L+ SQL++ K+V+PTI VCQEQLI + + V ++++ +++ AT+ EL AA+ V +AL L++H+R+ + + + + A + I + + S D ++V AR LAQAT+ +++ ++ A E + KL+ AAK LA+AT ++++AK + + + LREA E V T I++++I+ L AA T T + +A+ K+ A++ ++ + +++ I L+ ++ ++ P+D AQL LI A ++++ P ++ S K PTV+D + L Q EL+ +A C +++ +AL ++ L L+ K + L PLP E ++ A L + + GS+ Q C G + + G ARE + AL L AARGVAASI + A ++++ + ++ + L+ EAK SP D + R Q + +S +L+ C++ LPGQ+D+DM K I + + +P N + ++EL T D NQ+ E+V+A R S ++ HD FDE A ++ + + V ++S LL K + +P + L A + + DSIN+L+T + T PGQKECD + LE++R +LDNP P++ YF+C++ +++ + + L +S+ I K + F DS+ + ++C L E Q +YLVGV D S+ G++GL D F + + I CQ + +P+++ Q ++S A +A+++ LC A + + + P K K + + L+ ++ L+ +F+E+NR + + + + V L + +FA A IS E +Q PI + ++LD++ +++ +++L + + + + + ++D++K LI+ I++ APGQ+ECD ++ + K I+ + + ++ SR S E+ Q L S + ++ H I+ +S A + E QL ++ E ++ + + A++ + Q +L+ T+ E++ Q+L A K+ GGNPKA+ H I E AQ + E+ +D++ L++ + + G V +VE+I ++ AK+ E ++ F + Q+ M+ + I+ A T+ + +P L +T Y L A QG +A T E G Q++ VQ +G I LV+ ++ P+ + + L + + +++ V+ L + N GTQAC A + I +D+DT+I+F + + ++ E F R +++ + LV + K++VS L ++A A T L + VK+G + S + + L+ + ++V +L + + +G DP LK K + +TSLLK +K+++D + +A++ I
Sbjct: 2 LDGAVKTIMVDDSKTVGELLVTICSRIGITNYEEYSLIQETVEEKKE-DGTGTLKKDRTLLRDERKMEKLKAKLHTDDDLNWLDHSRTFREQGVDDNETLLLRRKFFYSDQNVDSRDPVQLNLLYVQARDDILNGSHPVSFDKACEFAGIQAQIQFGSHIEHKHKPGFLDLKEFLPKEYIKQ-RGAEKKIFQEHKNCGEMTEIEAKVKYVKLARSLRTYGVSFFLVKEKMKSKNKLVPRLLGITKESVMRVDEKTKDVVQEWPLTTVKRWAASPKSFTLDFGEYQ-ESYYSVQTTEGEQISQLIAGYIDIILKKKQSKDRFGLEGDEESTMLEESVSPKKSTILQQQFNRVGRVEHGSVALPGV------------IRSGSIGTESL--------------------TLGTMPSPQQQITMGQMHRGHMPPLSSAQQALMGTINTSMQAVQKAQIDLGEVDNLPPLGQDMASKVWIQNKMDESKHEIHSQVDAITAGTASVVNLTAGDPTDTDYTAVGCAITTISSNLTEMSKGVKLLAALME-------------DDVGGGNDLMKAARTLAGAVSDLLKAVEPASGEP----RQTVLTAAGSIGQASGDLLRQIGENET-------------------DERFQDVLMNLAKAVANAAAMLVLKAKNVAQVAEDTVLQNRVIAAATQCALSTSQLVACAKVVSPTISSPVCQEQLIEAGKLVDRSVESCIQACLSATEDGELLKQVSAAASVVSQALADLLQHVRQYTSRGEPIGRYDQATDTIMTVTESIFISMGDAGEMVRQARVLAQATSDLVNAMRSDA--EAEVDVDNSKKLLAAAKLLADATARMVEAAKGAAAYPENEDQQQRLREAAEGLRVAT-NAAAQNAIKKKLINRLENAAKQAAAAATQTIAAAQNAAASNKNTAAHQQLVQSCKAVADHIPQLVQGVRSSQAKPEDLSAQLALIIASQNFLQPGSKMVTSAKSSVPTVTDQAAAMQLGQCAKNLATCLAELRTAAQKAHEACGPMEIDSALTAIQTLRSELQDAKLAATTTQLKPLPGESLEKCAQDLGSTSKSVGSSMAQLLT-----CAA----QGNEHF--------TGIAARETAQALKTLAQAARGVAASI-------------TDPKASAAMLDSARDVMEGSALLIHEAKQALISPADAESQQRLAQVAKAVSHSLNNCVNCLPGQKDVDMALKSIGEASKKLLMDAIP---PANKSFQEAQNELNQTAADLNQSAGEVVTA------------TRGSSSQLAVASGKFSHD-FDEFLDAGIEMAGHTQKKDDQVQVISNLKNISMASSKLLLAAKSLSVDPAAANAKNLLAAAARAVTDSINQLIT-LCTQQAPGQKECDNALRELEAVRGMLDNPSEPVNDLSYFDCIESVMENS-KVLGESMAGISQNCKISDVTAFGDSVGSASKALCGLTEAAGQASYLVGVSDPNSQAGHQGLVDPIQFAKANQAIQMACQNLVDPESSPSQ----VLSAATIVAKHTSALCNACRLASSKTTNPVAKRHFVQSAKEVANSTANLVKTIKALDGDFSEENRSRCQVATTPLIEAVENLTTFASNPEFASVPAQISNEGSAAQEPIIQSARSMLDSSTLLLKTARSLALNPKDPPTWSVLAGHSRTVSDSIKSLITAIRDKAPGQRECDSSIDNINKCIRDIEQASLAVVSQ--NLPSRDDISLEALQEQLTSTVQEIGHLIDPVSTAARGEASQLGHKVTQLAGYFEPLIKASVGVASKLNDHQQQMTFLDQTKTLAESALQMLYAAKEGGGNPKASHTHDAIAEAAQLMKEAVDDIMVTLNEAASEVGMVGGMVESIAEAMAKLDEGTPPEDEGSFVDYQTSMV-------KHSKAIAVTAQEMMTKSVTSPDELGALASQVTVDYSQL--AVQGRLASHTAEPEEIGFQIKTRVQELGHGCIYLVQKAGALQISPTDSFTKRELIECARAVTEKVSLVLSALQAGNKGTQACITAASAVSGIIADLDTTIMFASAGTLNAENDES------FADHRENILKTAKALVEDTKMLVSGAASGQERLAQAAQSSAKTITQLTDVVKLGAASIGSDDPETQVVLINAVKDVAKALAELISATKCAAGKAADDPSMYQLKSAAKVMVTNVTSLLKTVKAVEDEATRGTRALEATI 2058
BLAST of Talin-1 vs. Ensembl Medaka
Match: tln2b (talin 2 [Source:NCBI gene;Acc:101167954]) HSP 1 Score: 832.787 bits (2150), Expect = 0.000e+0 Identity = 601/1922 (31.27%), Postives = 1017/1922 (52.91%), Query Frame = 1
Query: 49 FELRIHIVDADVTKIVPLDPEATIFQLCETIRKNIREAQTKSPKSYGLYLPHDDLKKGLWLDNSKTLQHYILKRGDTIEYRNRSRWLHIRTMDGTNKTLKVDDSWTVSELMLTVCTKLGIYNYDEYSLIS----DKMDFSPGI---DKTLSMKRGISINXXXXXXXXXXXXYHTEDGLNWLNPSQSLRQQGIEESEVLLLKRKYFFSDMNVDSRDPIQLSLLYEQLKDAVINGTHPVTLPEAIELAGLQCQVQLGNYSADKFKPGFLDLRECLPKEYQKNPKTVEKKIFNQHSKSKDLSEVEAKEKYCLLCRSFKTYGITFFLVKEKVIGKNKLIPRLLGVNKESVVQVDEKTKEIINTWPLTSIRKWAASFNGFTMDFGEYSPDEYYTAQTDKGERISQLIAGYIDIILKRKKAKDHLGVDADEESIMYEENIAPSKAIIVEH----VPKQKRSSVSEEDVVIRKKAHMANSSVRMNSQASDSVCSQDCTDFYQEDINMSRQTSSLGRTQSPSSSLTTNSMH-YRMSDDDIRQKLYIISLQDNLDTIQKYKDQLMIENKGPEIGKDEASQQWIYVNIDNSRQRMADEIGAMNAAVAQVLRSAQGLATIXXXXXXXXXXXXIAKMQNSFSLITVHLPSLMEEIRTAAYYQDQLTDEDVSGEELIAAAKRLADAFTNLIKAAYPVEDQKRSLNRKEIFDAANAVGEASSDLLQQITEQENCQIELKSERPYSIIMITEEDQLYQEELLRLAKSVANETTNLIKQVKVIAVEAENPSDQKKVVMAATETGLAISQLISTTKIVAPTIEQSVCQEQLIFSIEDVSKAIQVVVESSNKATQSEELQDLTVQAANQVQEALDTLMKHLRXXXXXXXXXXXXXXAYENI----QEXXXXXXXXXXXXXXXRRLAQATTAMISEIQLKAVNEQYKTPEERDKLINAAKQLAEATTVLIDSAKNCTMDKDEMNLRYTLREATERFIVVTYTTECATYIQEQVIDHLLVAARKAATTGTHLINTSLSAA--KKSRASNFKVCNDGRELSNQISNLIVAIKEARRDPKDHLAQLELIAACRDYIDPSEQLSQSNKYMWPTVSDPSLQTALNQSINQSVIATEELKKCVHQADLMCQHLDLSAALEQLKRLEQNLKSIKNSIERENLIPLPDEKSDESAALLIKSVRRSGSAANQFKNDLESRCVVYEQTNGEDSYQNLENLDVAGQKARELSMALDRLVHAARGVAASIEFENQESENNDKNLEKLAQLQIVNNCLEAVKAARDLVIEAKSS---PPDNDQMDRAQQASVRXXXXXXXXXXXXPGQRDLDMLSKHIESKKHQFAENRLPIQQNNNINLSNCRSELTDTTFDFNQAVNELVSAPSFNLVNKGCKKMRMSYDRIVEICNVLVHDPFDES-DSALH---HLSSNRDHIA--NGVMIMSEDCQTLLDKVKKIQCEPDNIIVRKQLQEATKMLLDSINRLLTNISTNLRPGQKECDKTIYRLESMRPILDNPVHPISHKDYFECLDFIIDKTVQPLADSLKNIPAAVKDENNQKFIDSIYHCADSVCMLLEETAQTAYLVGVGDVRSKIGNKGLADHTSFLQIQKEISENCQTICNPDTTARQDSSLMISTAGQIAENSRKLCEASK--TIMISFPNDKIKLSDKTKITLLAVSELMTGVQNLNQNFNEDNRKEVESLSGKVQDNVAELVQLLLSYKFAGDAAIISEEAKESQGPIKAAGITVLDTAIEVIQCSKALISSEANEELFIAYSSSCKDLNDALKHLISTIKESAPGQKECDEXXXXXXXXXXQAYDSKMKIMKHRSRTIS-RTFESEESYQNILQSALIQMPHCINELSRAGKKEPEQLARIFSRQTQLLESMVNSCICAANQTDLIQNSNIYLEHLITILEASEQLLKAVKKSGGNPK 5724
L+I + +V K + +P ++ C IR+ + EAQT YGL+L DD +KG+WL++ +TL +Y+L+ GD +EY+ + R I+ +DGT KT+ VDDS TV EL++T+C+++GI NY+EYS+I DK D G D+TL ++ D+ K++KLK K HT+D LNWL+ S++ R+QG+EESE LLL+RK+F+SD NVDSRDP+QL+LLY Q +D +ING+HPV+ +A E AG+Q Q+Q G + K KPGFLDL+E LPKEY K + EKK+F +H +++E+E K KY L RS +TYG++FFLVKEK+ GKNKL+PRLLG+ KESV++VDEKTK+++ WPLT++++WAAS FT+DFGEY + YY+ QT +GE+ISQLIAGYIDIILK+K++KDH G++ DEES M EE+++P ++ I++ V + + SV+ ++ S S+ D T ++G S +TT MH M + Q+ + ++ ++ +Q+ + L + P +G D AS+ W+ +D S+ + ++ A+ A A V+ G E E + + + I+ +L + + ++ A D DE SG +L+ AA+ LA A ++L+++ P + R + + AA ++G+AS DLL+ + E E D+ +Q+ L+ LAK+VAN L+ + K +A AE+ + Q +V+ AAT+ L+ SQL++ TK+V+PTI VCQEQL+ + + V ++++ V++ A+ EL AA V +AL L++H+R + + + A + I + + S D ++V AR LAQAT+ +++ ++ A E + KL+ AAK LA+AT ++++AK + + + LREA E V T I++++++ L +AA++AA T I + +AA K+ AS+ ++ + + +++ I L+ I+ ++ P++ QL LI A ++++ P ++ S K PTV+D + L Q EL+ +A C L++ +AL+ ++ L+ L+ K S+ L PLP E ++ A L + + GS+ Q C G + Y G ARE + AL L AARGVAA + E A ++++ ++ + L+ EA + P D D R Q + +S +L+ C++ LPGQ+D+DM + I + + LP + + +++L T + N + E+V + + S D FDE D+ + H S D I + +S LL K + +P + L A + + +S+N+L+T + T GQKECD + LE++R +LDNP PI+ YF+C++ +++ + + L +S+ I K + Q F +S+ + ++C L E Q +YLVGV D S+ G++GL D F + + I CQ + +P ++ Q ++S A +A+++ LC A + + S P + + K + L+ ++ L+ +F+E+NR + + + V L + +F A IS E +Q PI + ++LD++ +I+ +++L+ + + + + + ++D++K LI++I++ APGQ+ECD ++ + K I+ D + + +T+ R S E+ Q L S++ ++ H I+ +S + E QL ++ + ++ + + A++ Q L+ T+ E++ Q+L A K+ GGNPK
Sbjct: 4 LSLKICVRQCNVVKTMQFEPSTPVYDACRIIRERVPEAQTGQASDYGLFLSDDDPRKGIWLESGRTLDYYMLRNGDILEYKKKQRPQKIKMLDGTIKTVMVDDSKTVGELLVTICSRIGITNYEEYSVIQELTEDKKDDGLGTLRKDRTLLLR-------DERKMEKLKAKLHTDDDLNWLDHSRTFREQGVEESETLLLRRKFFYSDQNVDSRDPVQLNLLYVQARDDIINGSHPVSFDKACEFAGIQAQIQFGPHVEHKHKPGFLDLKEFLPKEYIKQ-RGAEKKVFQEHKNCGEMTEIEGKVKYVKLARSLQTYGVSFFLVKEKMKGKNKLVPRLLGITKESVMRVDEKTKDVVQEWPLTTVKRWAASPKSFTLDFGEYQ-ESYYSVQTTEGEQISQLIAGYIDIILKKKQSKDHFGLEGDEESTMLEESVSPKRSTILQQQFNRVGRVEHGSVALPGII-----------------RSGSIGGPD--------------TFNMGTMPSAQQQITTGQMHKGHMPPLSLAQQALMGTINSSMQAVQQAQADLGHVDNLPPLGHDLASRVWVQNKVDESKHEIHSQVDAITAGTASVVNLTAG----------EPAETDYTAVGCAITTISSNLTEMSKGVKLLAALMD---DEVGSGHKLMGAARMLAGAVSDLLRSVEPAAAEPR----QTVLTAAGSIGQASGDLLRHMGEGET-------------------DEKFQDTLMNLAKAVANAAAMLVLKAKNVAQVAEDTTLQNRVIAAATQCALSTSQLVACTKVVSPTISSPVCQEQLVEAGKLVDRSVETCVKACRSASDDGELLKQVAAAAGVVSQALSDLLQHVRHYASCGEPIGRYDQATDTIMNVTENIFTSMGDAGEMVRQARVLAQATSDLVNAMRSDA--EAEVDVDNSKKLLAAAKLLADATARMVEAAKGAAAYPENEDQQQRLREAAEGLRVAT-NAAAQNAIKKKLVNRLEIAAKQAAAAATQTIAAAQNAAISNKNTASHQQLVHSCKAVADSIPQLVQGIRSSQAQPEELGPQLTLIMASQNFLQPGSKMVSSAKSAVPTVADQAAAMQLGQCAKNLATCLAELRTATQKAHEACGPLEIDSALKTVQTLKCELQDAKISVIDAQLKPLPGETLEKCAQDLGSTSKAVGSSMAQLLT-----CAA----QGNEHY--------TGVAARETAQALRTLAQAARGVAACTK-------------EPQAAAAMLDSAQCVMEGSAMLIHEAHQALVHPGDADSQQRLAQVAKAVSHSLNNCVNCLPGQKDVDMALRSIGEASKKLLVDFLP---PCSKSFQEAQTDLNHTAAELNHSAGEVVHSSRGTSRQLAAASGKFSQD-------------FDEFLDAGIEMAGHTQSKEDKIQVIGNLKNISMASSKLLLAAKSLSVDPGAANAKNLLAVAARAVTESVNQLIT-LCTQQAAGQKECDNALRELEAVRGLLDNPNEPINELSYFDCIESVMENS-KVLGESMAGISQHCKTGDVQAFGESVSLASKALCGLTEAAGQASYLVGVSDPNSQSGHEGLVDPIQFARAHQAIQTACQNLVDPASSPSQ----VLSAATIVAKHTSALCNACRLASSKTSNPVARRQFVQSAKEVANTTANLVKTIKGLDGDFSEENRNRCRLATAPLLEAVENLATFANNPEFVSAPAQISNEGSAAQEPIVRSARSMLDSSTYLIETARSLVLNPKDPPSWSILAGHSRTVSDSIKSLITSIRDKAPGQRECDYSIDNINKCIR---DIEQASLAAVGQTLPCRDDISMEALQEQLTSSVQEIGHLIDPVSTTARGEAAQLGHKVTQLASYFDPLIVASVGLASKLQDHQQQMTILDQTKTLSESALQMLYAAKEGGGNPK 1791 HSP 2 Score: 87.0409 bits (214), Expect = 5.194e-16 Identity = 70/254 (27.56%), Postives = 121/254 (47.64%), Query Frame = 1
Query: 6073 AVATLSNENNGKQLQECVQTVGKVSISLVKSTTEVRPSVASSISN--LQAKTQELHKRIDDVIQLLISSNVGTQACTQAIKILKEINSDIDTSILFVKSADIQNDDREYYSVKELFKKSRNSVIDNSSELVRNIKLIVSKDVCDVNILQESADQIAITSQSLANDVKVGLEHLNSSTSQYNIELLVSFQEVIVSLISFLEVARNTSGLPYTDPLFQNLKEEGKCSINAITSLLKVLKSMDDVNLKDFQAIDNAI 6828
A+A + E Q++ VQ +G I LV+ ++ S S S L + + +++ V+ L + N GTQAC A + I +D+DT+I+F SA N + E E F R S++ + LV + KL+V+ L ++A A T L VK+G + S + + L+ + ++V +L + + +G P DP LK K + +TSLLK +K+++D + +A++ I
Sbjct: 1817 AIAITAQEMVAFQIRTRVQELGHGCIFLVQKAGALQLSPTDSFSKRELIECARSVTEKVSLVLSALQAGNKGTQACITAASAVSGIIADLDTTIMFA-SAGTLNPENE-----ESFADHRESILKTAKALVEDTKLLVAGAASTQEKLAQAAHSSAKTITQLTEVVKLGATSMGSENPETQVVLINAVRDVAKALAELIGATKCAAGKPPDDPSMYQLKGAAKVMVTNVTSLLKTVKAVEDEATRGTRALEATI 2064
BLAST of Talin-1 vs. Planmine SMEST
Match: SMESG000066444.1 (SMESG000066444.1) HSP 1 Score: 5274.52 bits (13681), Expect = 0.000e+0 Identity = 2671/2685 (99.48%), Postives = 2675/2685 (99.63%), Query Frame = 1
Query: 22 SPMLNSNGNFELRIHIVDADVTKIVPLDPEATIFQLCETIRKNIREAQTKSPKSYGLYLPHDDLKKGLWLDNSKTLQHYILKRGDTIEYRNRSRWLHIRTMDGTNKTLKVDDSWTVSELMLTVCTKLGIYNYDEYSLISDKMDFSPGIDKTLSMKRGISINXXXXXXXXXXXXYHTEDGLNWLNPSQSLRQQGIEESEVLLLKRKYFFSDMNVDSRDPIQLSLLYEQLKDAVINGTHPVTLPEAIELAGLQCQVQLGNYSADKFKPGFLDLRECLPKEYQKNPKTVEKKIFNQHSKSKDLSEVEAKEKYCLLCRSFKTYGITFFLVKEKVIGKNKLIPRLLGVNKESVVQVDEKTKEIINTWPLTSIRKWAASFNGFTMDFGEYSPDEYYTAQTDKGERISQLIAGYIDIILKRKKAKDHLGVDADEESIMYEENIAPSKAIIVEHVPKQKRSSVSEEDVVIRKKAHMANSSVRMNSQASDSVCSQDCTDFYQEDINMSRQTSSLGRTQSPSSSLTTNSMHYRMSDDDIRQKLYIISLQDNLDTIQKYKDQLMIENKGPEIGKDEASQQWIYVNIDNSRQRMADEIGAMNAAVAQVLRSAQGLATIXXXXXXXXXXXXIAKMQNSFSLITVHLPSLMEEIRTAAYYQDQLTDEDVSGEELIAAAKRLADAFTNLIKAAYPVEDQKRSLNRKEIFDAANAVGEASSDLLQQITEQENCQIELKSERPYSIIMITEEDQLYQEELLRLAKSVANETTNLIKQVKVIAVEAENPSDQKKVVMAATETGLAISQLISTTKIVAPTIEQSVCQEQLIFSIEDVSKAIQVVVESSNKATQSEELQDLTVQAANQVQEALDTLMKHLRXXXXXXXXXXXXXXAYENIQEXXXXXXXXXXXXXXXRRLAQATTAMISEIQLKAVNEQYKTPEERDKLINAAKQLAEATTVLIDSAKNCTMDKDEMNLRYTLREATERFIVVTYTTECATYIQEQVIDHLLVAARKAATTGTHLINTSLSAAKKSRASNFKVCNDGRELSNQISNLIVAIKEARRDPKDHLAQLELIAACRDYIDPSEQLSQSNKYMWPTVSDPSLQTALNQSINQSVIATEELKKCVHQADLMCQHLDLSAALEQLKRLEQNLKSIKNSIERENLIPLPDEKSDESAALLIKSVRRSGSAANQFKNDLESRCVVYEQTNGEDSYQNLENLDVAGQKARELSMALDRLVHAARGVAASIEFENQESENNDKNLEKLAQLQIVNNCLEAVKAARDLVIEAKSSPPDNDQMDRAQQASVRXXXXXXXXXXXXPGQRDLDMLSKHIESKKHQFAENRLPIQQNNNINLSNCRSELTDTTFDFNQAVNELVSAPSFNLVNKGCKKMRMSYDRIVEICNVLVHDPFDESDSALHHLSSNRDHIANGVMIMSEDCQTLLDKVKKIQCEPDNIIVRKQLQEATKMLLDSINRLLTNISTNLRPGQKECDKTIYRLESMRPILDNPVHPISHKDYFECLDFIIDKTVQPLADSLKNIPAAVKDENNQKFIDSIYHCADSVCMLLEETAQTAYLVGVGDVRSKIGNKGLADHTSFLQIQKEISENCQTICNPDTTARQDSSLMISTAGQIAENSRKLCEASKTIMISFPNDKIKLSDKTKITLLAVSELMTGVQNLNQNFNEDNRKEVESLSGKVQDNVAELVQLLLSYKFAGDAAIISEEAKESQGPIKAAGITVLDTAIEVIQCSKALISSEANEELFIAYSSSCKDLNDALKHLISTIKESAPGQKECDEXXXXXXXXXXQAYDSKMKIMKHRSRTISRTFESEESYQNILQSALIQMPHCINELSRAGKKEPEQLARIFSRQTQLLESMVNSCICAANQTDLIQNSNIYLEHLITILEASEQLLKAVKKSGGNPKANSVHSQIDEMAQGVIESCEDLLAALDKISFKQGNVNTIVETITKSSAKVQESAIIPEKSRFGNSQSKMLDICYDMNNLTTDISSNANSESTQRLLAPLTQNLTQRYDDLCRACQGAVATLSNENNGKQLQECVQTVGKVSISLVKSTTEVRPSVASSISNLQAKTQELHKRIDDVIQLLISSNVGTQACTQAIKILKEINSDIDTSILFVKSADIQNDDREYYSVKELFKKSRNSVIDNSSELVRNIKLIVSKDVCDVNILQESADQIAITSQSLANDVKVGLEHLNSSTSQYNIELLVSFQEVIVSLISFLEVARNTSGLPYTDPLFQNLKEEGKCSINAITSLLKVLKSMDDVNLKDFQAIDNAIIXXXXXXXXXXXXXXGISREASPVESPTSTNRLSIGSDITVSPRFAPEEINRLIPSLANVCDKILEISSPEFKPIIRQENISVVSISCSKVNNELTSACKNLLRNGPVTDSKKQTLNTVDQLVENYTELLKNFKLYLTNPTKETRIPVETVVSKLNELIKLLRDQVNLLREGPRLVMYFRPSSPEWRDVSEKYIGRHVAYHHCFVKSYNHDSHTSLHHHQAPFIQLPINTRDPSEVDLDTAKNQIKFVTTKLIDIKLNPDLIGKDKCSVAEVDQMLSYIKDIGWSTEELLSSSQEICKSNSDTDNEIWNIDFKKEIFKSAIGVSNAMKDLCEAASKPLSTGCSPTWGDRMSTSTRKVANSTGQLLLNLKPTVIQNKSQIEKIHTHGNQIKKNTDLLLNHLNCINDRKWGEASLNAS 8076
SPMLNSNGNFELRIHIVDADVTKIVPLDPEATIFQLCETIRKNIREAQTKSPKSYGLYLPHDDLKKGLWLDNSKTLQHYILKRGDTIEYRNRSRWLHIRTMDGTNKTLKVDDSWTVSELMLTVCTKLGIYNYDEYSLISDKMDFSPGIDKTLSMK GISINKDQEKLDKLKKKYHTEDGLNWLNPSQSLRQQGIEESEVLLLKRKYFFSDMNVDSRDPIQLSLLYEQLKDAVINGTHPVTLPEAIELAGLQCQVQLGNYSADKFKPGFLDLRECLPKEYQKNPKTVEKKIFNQHSKSKDLSEVEAKEKYCLLCRSFKTYGITFFLVKEKVIGKNKLIPRLLGVNKESVVQVDEKTKEIINTWPLTSIRKWAASFNGFTMDFGEYSPDEYYTAQTDKGERISQLIAGYIDIILKRKKAKDHLGVDADEESIMYEENIAPSKAIIVEHVPKQKRSSVSEEDVVIRKKAHMANSSVRMNSQASDSVCSQD TDFYQEDINMSRQTSSLGRTQSPSSSLTTNSMHYRMSDDDIRQKLYIISLQDNLDTIQKYKDQLMIENKGPEIGKDEASQQWIYVNIDNSRQRMADEIGAMNAAVAQVLRSAQGLATIEE+EEEEMNEEMIAKMQNSFSLITVHLPSLMEEIRTAAYYQDQLTDEDVSGEELIAAAKRLADAFTNLIKAAYPVEDQKRSLNRKEIFDAANAVGEASSDLLQQITEQENCQIELKSERPYSIIMITEEDQLYQEELLRLAKSVANETTNLIKQVKVIAVEAENPSDQKKVVMAATETGLAISQLISTTKIVAPTIEQSVCQEQLIFSIEDVSKAIQVVVESSNKATQSEELQDLTVQAANQVQEALDTLMKHLRKDFDKNDKLDNFLLAYENIQEVDDSDDDLDKLVSAARRLAQATTAMISEIQLKAVNEQYKTPEERD+LINAAKQLAEATTVLIDSAKNCTMDKDEMNLRYTLREATERFIVVTYTTECATYIQEQVIDHLLVAARKAATTGTHLINTSLSAAKKSRASNFKVCNDGRELSNQISNLIVAIKEARRDPKDHLAQLELIAACRDYIDPSEQLSQSNKYMWPTVSDPSLQTALNQSINQSVIATEELKKCVHQADLMCQHLDLSAALEQLKRLEQNLKSIKNSIERENLIPLPDEKSDESAALLIKSVRRSGSAANQFKNDLESRCVVYEQTNGEDSYQNLENLD AGQKARELSMALDRLVHAARGVAASIEFENQESENNDKNLEKLAQLQIVNNCLEAVKAARDLVIEAKSSPPDNDQMDRAQQASVRLSDALSLCLDSLPGQRDLDMLSKHIESKKHQFAENRLPIQQNNNINLSNCRSELTDTTFDFNQAVNELVSAPSFNLVNKGCKKMRMSYDRIVEICNVLVHDPFDESDSALHHLSSNRDHIANGVMIMSEDCQTLLDKVKKIQCEPDNIIVRKQLQEATKMLLDSINRLLTNISTNLRPGQKECDKTIYRLESMRPILDNPVHPISHKDYFECLDFIIDKTVQPLADSLKNIPAAVKDENNQKFIDSIYHCADSVCMLLEETAQTAYLVGVGDVRSKIGNKGLADHTSFLQIQKEISENCQTICNPDTTARQ MISTAGQIAENSRKLCEASKTIMISFPNDKIKLSDKTKITLLAVSELMTGVQNLNQNFNEDNRKEVESLSGKVQDNVAELVQLLLSYKFAGDAAIISEEAKESQGPIKAAGITVLDTAIEVIQCSKALISSEANEELFIAYSSSCKDLNDALKHLISTIKESAPGQKECDEALAILAKLIKQAYDSKMKIMKHRSRTISRTFESEESYQNILQSALIQMPHCINELSRAGKKEPEQLARIFSRQTQLLESMVNSCICAANQTDLIQNSNIYLEHLI ILEASEQLLKA+KKSGGNPKANSVHSQIDEMAQGVIESCEDLLAALDKISFKQGNVNTIVETITKSSAKVQESAIIPEKSRFGNSQSKMLDICYDMNNLTTDISSNANSESTQRLLAPLTQNLTQRYDDLCRACQGAVATLSNENNGKQLQECVQTVGKVSISLVKSTTEVRPSVASSISNLQAKTQELHKRIDDVIQLLISSNVGTQACTQAIKILKEINSDIDTSILFVKSADIQNDDREYYSVKELFKKSRNSVIDNSSELVRNIKLIVSKDVCDVNILQESADQIAITSQSLANDVKVGLEHLNSSTSQYNIELLVSFQEVIVSLISFLEVARNTS LPYTDPLFQNLKEEGKCSINAITSLLKVLKSMDDVNLKDFQAIDNAIIELEHNHECLLELENGISREASPVESPTSTNRLSIGSDITVSPRFAPEEINRLIPSLANVCDKILEISSPEFKPIIRQENISVVSISCSKVNNELTSACKNLLRNGPVTDSKKQTLNTVDQLVENYTELLKNFKLYLTNPTKETRIPVETVVSKLNELIKLLRDQVNLLREGPRLVMYFRPSSPEWRDVSEKYIGRHVAYHHCFVKSYNHDSHTSLHHHQAPFIQLPINTR PSEVDLDTAKNQIKFVTTKLIDIKLNPDLIGKDKCSVAEVDQMLSYIKDIGWSTEELLSSSQEICKSNSDTDNEIWNIDFKKEIFKSAIGVSNAMKDLCEAASKPLSTGCSPTWGDRMSTSTRKVANSTGQLLLNLKPTVIQNKSQIEKIHTHGNQIKKNTDLLLNHLNCINDRKWGEASLNA+
Sbjct: 9 SPMLNSNGNFELRIHIVDADVTKIVPLDPEATIFQLCETIRKNIREAQTKSPKSYGLYLPHDDLKKGLWLDNSKTLQHYILKRGDTIEYRNRSRWLHIRTMDGTNKTLKVDDSWTVSELMLTVCTKLGIYNYDEYSLISDKMDFSPGIDKTLSMKHGISINKDQEKLDKLKKKYHTEDGLNWLNPSQSLRQQGIEESEVLLLKRKYFFSDMNVDSRDPIQLSLLYEQLKDAVINGTHPVTLPEAIELAGLQCQVQLGNYSADKFKPGFLDLRECLPKEYQKNPKTVEKKIFNQHSKSKDLSEVEAKEKYCLLCRSFKTYGITFFLVKEKVIGKNKLIPRLLGVNKESVVQVDEKTKEIINTWPLTSIRKWAASFNGFTMDFGEYSPDEYYTAQTDKGERISQLIAGYIDIILKRKKAKDHLGVDADEESIMYEENIAPSKAIIVEHVPKQKRSSVSEEDVVIRKKAHMANSSVRMNSQASDSVCSQDGTDFYQEDINMSRQTSSLGRTQSPSSSLTTNSMHYRMSDDDIRQKLYIISLQDNLDTIQKYKDQLMIENKGPEIGKDEASQQWIYVNIDNSRQRMADEIGAMNAAVAQVLRSAQGLATIEENEEEEMNEEMIAKMQNSFSLITVHLPSLMEEIRTAAYYQDQLTDEDVSGEELIAAAKRLADAFTNLIKAAYPVEDQKRSLNRKEIFDAANAVGEASSDLLQQITEQENCQIELKSERPYSIIMITEEDQLYQEELLRLAKSVANETTNLIKQVKVIAVEAENPSDQKKVVMAATETGLAISQLISTTKIVAPTIEQSVCQEQLIFSIEDVSKAIQVVVESSNKATQSEELQDLTVQAANQVQEALDTLMKHLRKDFDKNDKLDNFLLAYENIQEVDDSDDDLDKLVSAARRLAQATTAMISEIQLKAVNEQYKTPEERDRLINAAKQLAEATTVLIDSAKNCTMDKDEMNLRYTLREATERFIVVTYTTECATYIQEQVIDHLLVAARKAATTGTHLINTSLSAAKKSRASNFKVCNDGRELSNQISNLIVAIKEARRDPKDHLAQLELIAACRDYIDPSEQLSQSNKYMWPTVSDPSLQTALNQSINQSVIATEELKKCVHQADLMCQHLDLSAALEQLKRLEQNLKSIKNSIERENLIPLPDEKSDESAALLIKSVRRSGSAANQFKNDLESRCVVYEQTNGEDSYQNLENLDAAGQKARELSMALDRLVHAARGVAASIEFENQESENNDKNLEKLAQLQIVNNCLEAVKAARDLVIEAKSSPPDNDQMDRAQQASVRLSDALSLCLDSLPGQRDLDMLSKHIESKKHQFAENRLPIQQNNNINLSNCRSELTDTTFDFNQAVNELVSAPSFNLVNKGCKKMRMSYDRIVEICNVLVHDPFDESDSALHHLSSNRDHIANGVMIMSEDCQTLLDKVKKIQCEPDNIIVRKQLQEATKMLLDSINRLLTNISTNLRPGQKECDKTIYRLESMRPILDNPVHPISHKDYFECLDFIIDKTVQPLADSLKNIPAAVKDENNQKFIDSIYHCADSVCMLLEETAQTAYLVGVGDVRSKIGNKGLADHTSFLQIQKEISENCQTICNPDTTARQ----MISTAGQIAENSRKLCEASKTIMISFPNDKIKLSDKTKITLLAVSELMTGVQNLNQNFNEDNRKEVESLSGKVQDNVAELVQLLLSYKFAGDAAIISEEAKESQGPIKAAGITVLDTAIEVIQCSKALISSEANEELFIAYSSSCKDLNDALKHLISTIKESAPGQKECDEALAILAKLIKQAYDSKMKIMKHRSRTISRTFESEESYQNILQSALIQMPHCINELSRAGKKEPEQLARIFSRQTQLLESMVNSCICAANQTDLIQNSNIYLEHLIAILEASEQLLKAIKKSGGNPKANSVHSQIDEMAQGVIESCEDLLAALDKISFKQGNVNTIVETITKSSAKVQESAIIPEKSRFGNSQSKMLDICYDMNNLTTDISSNANSESTQRLLAPLTQNLTQRYDDLCRACQGAVATLSNENNGKQLQECVQTVGKVSISLVKSTTEVRPSVASSISNLQAKTQELHKRIDDVIQLLISSNVGTQACTQAIKILKEINSDIDTSILFVKSADIQNDDREYYSVKELFKKSRNSVIDNSSELVRNIKLIVSKDVCDVNILQESADQIAITSQSLANDVKVGLEHLNSSTSQYNIELLVSFQEVIVSLISFLEVARNTSELPYTDPLFQNLKEEGKCSINAITSLLKVLKSMDDVNLKDFQAIDNAIIELEHNHECLLELENGISREASPVESPTSTNRLSIGSDITVSPRFAPEEINRLIPSLANVCDKILEISSPEFKPIIRQENISVVSISCSKVNNELTSACKNLLRNGPVTDSKKQTLNTVDQLVENYTELLKNFKLYLTNPTKETRIPVETVVSKLNELIKLLRDQVNLLREGPRLVMYFRPSSPEWRDVSEKYIGRHVAYHHCFVKSYNHDSHTSLHHHQAPFIQLPINTRYPSEVDLDTAKNQIKFVTTKLIDIKLNPDLIGKDKCSVAEVDQMLSYIKDIGWSTEELLSSSQEICKSNSDTDNEIWNIDFKKEIFKSAIGVSNAMKDLCEAASKPLSTGCSPTWGDRMSTSTRKVANSTGQLLLNLKPTVIQNKSQIEKIHTHGNQIKKNTDLLLNHLNCINDRKWGEASLNAT 2689
BLAST of Talin-1 vs. Planmine SMEST
Match: SMESG000066444.1 (SMESG000066444.1) HSP 1 Score: 5272.98 bits (13677), Expect = 0.000e+0 Identity = 2671/2685 (99.48%), Postives = 2675/2685 (99.63%), Query Frame = 1
Query: 22 SPMLNSNGNFELRIHIVDADVTKIVPLDPEATIFQLCETIRKNIREAQTKSPKSYGLYLPHDDLKKGLWLDNSKTLQHYILKRGDTIEYRNRSRWLHIRTMDGTNKTLKVDDSWTVSELMLTVCTKLGIYNYDEYSLISDKMDFSPGIDKTLSMKRGISINXXXXXXXXXXXXYHTEDGLNWLNPSQSLRQQGIEESEVLLLKRKYFFSDMNVDSRDPIQLSLLYEQLKDAVINGTHPVTLPEAIELAGLQCQVQLGNYSADKFKPGFLDLRECLPKEYQKNPKTVEKKIFNQHSKSKDLSEVEAKEKYCLLCRSFKTYGITFFLVKEKVIGKNKLIPRLLGVNKESVVQVDEKTKEIINTWPLTSIRKWAASFNGFTMDFGEYSPDEYYTAQTDKGERISQLIAGYIDIILKRKKAKDHLGVDADEESIMYEENIAPSKAIIVEHVPKQKRSSVSEEDVVIRKKAHMANSSVRMNSQASDSVCSQDCTDFYQEDINMSRQTSSLGRTQSPSSSLTTNSMHYRMSDDDIRQKLYIISLQDNLDTIQKYKDQLMIENKGPEIGKDEASQQWIYVNIDNSRQRMADEIGAMNAAVAQVLRSAQGLATIXXXXXXXXXXXXIAKMQNSFSLITVHLPSLMEEIRTAAYYQDQLTDEDVSGEELIAAAKRLADAFTNLIKAAYPVEDQKRSLNRKEIFDAANAVGEASSDLLQQITEQENCQIELKSERPYSIIMITEEDQLYQEELLRLAKSVANETTNLIKQVKVIAVEAENPSDQKKVVMAATETGLAISQLISTTKIVAPTIEQSVCQEQLIFSIEDVSKAIQVVVESSNKATQSEELQDLTVQAANQVQEALDTLMKHLRXXXXXXXXXXXXXXAYENIQEXXXXXXXXXXXXXXXRRLAQATTAMISEIQLKAVNEQYKTPEERDKLINAAKQLAEATTVLIDSAKNCTMDKDEMNLRYTLREATERFIVVTYTTECATYIQEQVIDHLLVAARKAATTGTHLINTSLSAAKKSRASNFKVCNDGRELSNQISNLIVAIKEARRDPKDHLAQLELIAACRDYIDPSEQLSQSNKYMWPTVSDPSLQTALNQSINQSVIATEELKKCVHQADLMCQHLDLSAALEQLKRLEQNLKSIKNSIERENLIPLPDEKSDESAALLIKSVRRSGSAANQFKNDLESRCVVYEQTNGEDSYQNLENLDVAGQKARELSMALDRLVHAARGVAASIEFENQESENNDKNLEKLAQLQIVNNCLEAVKAARDLVIEAKSSPPDNDQMDRAQQASVRXXXXXXXXXXXXPGQRDLDMLSKHIESKKHQFAENRLPIQQNNNINLSNCRSELTDTTFDFNQAVNELVSAPSFNLVNKGCKKMRMSYDRIVEICNVLVHDPFDESDSALHHLSSNRDHIANGVMIMSEDCQTLLDKVKKIQCEPDNIIVRKQLQEATKMLLDSINRLLTNISTNLRPGQKECDKTIYRLESMRPILDNPVHPISHKDYFECLDFIIDKTVQPLADSLKNIPAAVKDENNQKFIDSIYHCADSVCMLLEETAQTAYLVGVGDVRSKIGNKGLADHTSFLQIQKEISENCQTICNPDTTARQDSSLMISTAGQIAENSRKLCEASKTIMISFPNDKIKLSDKTKITLLAVSELMTGVQNLNQNFNEDNRKEVESLSGKVQDNVAELVQLLLSYKFAGDAAIISEEAKESQGPIKAAGITVLDTAIEVIQCSKALISSEANEELFIAYSSSCKDLNDALKHLISTIKESAPGQKECDEXXXXXXXXXXQAYDSKMKIMKHRSRTISRTFESEESYQNILQSALIQMPHCINELSRAGKKEPEQLARIFSRQTQLLESMVNSCICAANQTDLIQNSNIYLEHLITILEASEQLLKAVKKSGGNPKANSVHSQIDEMAQGVIESCEDLLAALDKISFKQGNVNTIVETITKSSAKVQESAIIPEKSRFGNSQSKMLDICYDMNNLTTDISSNANSESTQRLLAPLTQNLTQRYDDLCRACQGAVATLSNENNGKQLQECVQTVGKVSISLVKSTTEVRPSVASSISNLQAKTQELHKRIDDVIQLLISSNVGTQACTQAIKILKEINSDIDTSILFVKSADIQNDDREYYSVKELFKKSRNSVIDNSSELVRNIKLIVSKDVCDVNILQESADQIAITSQSLANDVKVGLEHLNSSTSQYNIELLVSFQEVIVSLISFLEVARNTSGLPYTDPLFQNLKEEGKCSINAITSLLKVLKSMDDVNLKDFQAIDNAIIXXXXXXXXXXXXXXGISREASPVESPTSTNRLSIGSDITVSPRFAPEEINRLIPSLANVCDKILEISSPEFKPIIRQENISVVSISCSKVNNELTSACKNLLRNGPVTDSKKQTLNTVDQLVENYTELLKNFKLYLTNPTKETRIPVETVVSKLNELIKLLRDQVNLLREGPRLVMYFRPSSPEWRDVSEKYIGRHVAYHHCFVKSYNHDSHTSLHHHQAPFIQLPINTRDPSEVDLDTAKNQIKFVTTKLIDIKLNPDLIGKDKCSVAEVDQMLSYIKDIGWSTEELLSSSQEICKSNSDTDNEIWNIDFKKEIFKSAIGVSNAMKDLCEAASKPLSTGCSPTWGDRMSTSTRKVANSTGQLLLNLKPTVIQNKSQIEKIHTHGNQIKKNTDLLLNHLNCINDRKWGEASLNAS 8076
SPMLNSNGNFELRIHIVDADVTKIVPLDPEATIFQLCETIRKNIREAQTKSPKSYGLYLPHDDLKKGLWLDNSKTLQHYILKRGDTIEYRNRSRWLHIRTMDGTNKTLKVDDSWTVSELMLTVCTKLGIYNYDEYSLISDKMDFSPGIDKTLSMK GISINKDQEKLDKLKKKYHTEDGLNWLNPSQSLRQQGIEESEVLLLKRKYFFSDMNVDSRDPIQLSLLYEQLKDAVINGTHPVTLPEAIELAGLQCQVQLGNYSADKFKPGFLDLRECLPKEYQKNPKTVEKKIFNQHSKSKDLSEVEAKEKYCLLCRSFKTYGITFFLVKEKVIGKNKLIPRLLGVNKESVVQVDEKTKEIINTWPLTSIRKWAASFNGFTMDFGEYSPDEYYTAQTDKGERISQLIAGYIDIILKRKKAKDHLGVDADEESIMYEENIAPSKAIIVEHVPKQKRSSVSEEDVVIRKKAHMANSSVRMNSQASDSVCSQD TDFYQEDINMSRQTSSLGRTQSPSSSLTTNSMHYRMSDDDIRQKLYIISLQDNLDTIQKYKDQLMIENKGPEIGKDEASQQWIYVNIDNSRQRMADEIGAMNAAVAQVLRSAQGLATIEE+EEEEMNEEMIAKMQNSFSLITVHLPSLMEEIRTAAYYQDQLTDEDVSGEELIAAAKRLADAFTNLIKAAYPVEDQKRSLNRKEIFDAANAVGEASSDLLQQITEQENCQIELKSERPYSIIMITEEDQLYQEELLRLAKSVANETTNLIKQVKVIAVEAENPSDQKKVVMAATETGLAISQLISTTKIVAPTIEQSVCQEQLIFSIEDVSKAIQVVVESSNKATQSEELQDLTVQAANQVQEALDTLMKHLRKDFDKNDKLDNFLLAYENIQEVDDSDDDLDKLVSAARRLAQATTAMISEIQLKAVNEQYKTPEERD+LINAAKQLAEATTVLIDSAKNCTMDKDEMNLRYTLREATERFIVVTYTTECATYIQEQVIDHLLVAARKAATTGTHLINTSLSAAKKSRASNFKVCNDGRELSNQISNLIVAIKEARRDPKDHLAQLELIAACRDYIDPSEQLSQSNKYMWPTVSDPSLQTALNQSINQSVIATEELKKCVHQADLMCQHLDLSAALEQLKRLEQNLKSIKNSIERENLIPLPDEKSDESAALLIKSVRRSGSAANQFKNDLESRCVVYEQTNGEDSYQNLENLD AGQKARELSMALDRLVHAARGVAASIEFENQESENNDKNLEKLAQLQIVNNCLEAVKAARDLVIEAKSSPPDNDQMDRAQQASVRLSDALSLCLDSLPGQRDLDMLSKHIESKKHQFAENRLPIQQNNNINLSNCRSELTDTTFDFNQAVNELVSAPSFNLVNKGCKKMRMSYDRIVEICNVLVHDPFDESDSALHHLSSNRDHIANGVMIMSEDCQTLLDKVKKIQCEPDNIIVRKQLQEATKMLLDSINRLLTNISTNLRPGQKECDKTIYRLESMRPILDNPVHPISHKDYFECLDFIIDKTVQPLADSLKNIPAAVKDENNQKFIDSIYHCADSVCMLLEETAQTAYLVGVGDVRSKIGNKGLADHTSFLQIQKEISENCQTICNPDTTARQ MISTAGQIAENSRKLCEASKTIMISFPNDKIKLSDKTKITLLAVSELMTGVQNLNQNFNEDNRKEVESLSGKVQDNVAELVQLLLSYKFAGDAAIISEEAKESQGPIKAAGITVLDTAIEVIQCSKALISSEANEELFIAYSSSCKDLNDALKHLISTIKESAPGQKECDEALAILAKLIKQAYDSKMKIMKHRSRTISRTFESEESYQNILQSALIQMPHCINELSRAGKKEPEQLARIFSRQTQLLESMVNSCICAANQTDLIQNSNIYLEHLI ILEASEQLLKA+KKSGGNPKANSVHSQIDEMAQGVIESCEDLLAALDKISFKQGNVNTIVETITKSSAKVQESAIIPEKSRFGNSQSKMLDICYDMNNLTTDISSNANSESTQRLLAPLTQNLTQRYDDLCRACQGAVATLSNENNGKQLQECVQTVGKVSISLVKSTTEVRPSVASSISNLQAKTQELHKRIDDVIQLLISSNVGTQACTQAIKILKEINSDIDTSILFVKSADIQNDDREYYSVKELFKKSRNSVIDNSSELVRNIKLIVSKDVCDVNILQESADQIAITSQSLANDVKVGLEHLNSSTSQYNIELLVSFQEVIVSLISFLEVARNTS LPYTDPLFQNLKEEGKCSINAITSLLKVLKSMDDVNLKDFQAIDNAIIELEHNHECLLELENGISREASPVESPTSTNRLSIGSDITVSPRFAPEEINRLIPSLANVCDKILEISSPEFKPIIRQENISVVSISCSKVNNELTSACKNLLRNGPVTDSKKQTLNTVDQLVENYTELLKNFKLYLTNPTKETRIPVETVVSKLNELIKLLRDQVNLLREGPRLVMYFRPSSPEWRDVSEKYIGRHVAYHHCFVKSYNHDSHTSLHHHQAPFIQLPINTR PSEVDLDTAKNQIKFVTTKLIDIKLNPDLIGKDKCSVAEVDQMLSYIKDIGWSTEELLSSSQEICKSNSDTDNEIWNIDFKKEIFKSAIGVSNAMKDLCEAASKPLSTGCSPTWGDRMSTSTRKVANSTGQLLLNLKPTVIQNKSQIEKIHTHGNQIKKNTDLLLNHLNCINDRKWGEASLNA+
Sbjct: 9 SPMLNSNGNFELRIHIVDADVTKIVPLDPEATIFQLCETIRKNIREAQTKSPKSYGLYLPHDDLKKGLWLDNSKTLQHYILKRGDTIEYRNRSRWLHIRTMDGTNKTLKVDDSWTVSELMLTVCTKLGIYNYDEYSLISDKMDFSPGIDKTLSMKHGISINKDQEKLDKLKKKYHTEDGLNWLNPSQSLRQQGIEESEVLLLKRKYFFSDMNVDSRDPIQLSLLYEQLKDAVINGTHPVTLPEAIELAGLQCQVQLGNYSADKFKPGFLDLRECLPKEYQKNPKTVEKKIFNQHSKSKDLSEVEAKEKYCLLCRSFKTYGITFFLVKEKVIGKNKLIPRLLGVNKESVVQVDEKTKEIINTWPLTSIRKWAASFNGFTMDFGEYSPDEYYTAQTDKGERISQLIAGYIDIILKRKKAKDHLGVDADEESIMYEENIAPSKAIIVEHVPKQKRSSVSEEDVVIRKKAHMANSSVRMNSQASDSVCSQDGTDFYQEDINMSRQTSSLGRTQSPSSSLTTNSMHYRMSDDDIRQKLYIISLQDNLDTIQKYKDQLMIENKGPEIGKDEASQQWIYVNIDNSRQRMADEIGAMNAAVAQVLRSAQGLATIEENEEEEMNEEMIAKMQNSFSLITVHLPSLMEEIRTAAYYQDQLTDEDVSGEELIAAAKRLADAFTNLIKAAYPVEDQKRSLNRKEIFDAANAVGEASSDLLQQITEQENCQIELKSERPYSIIMITEEDQLYQEELLRLAKSVANETTNLIKQVKVIAVEAENPSDQKKVVMAATETGLAISQLISTTKIVAPTIEQSVCQEQLIFSIEDVSKAIQVVVESSNKATQSEELQDLTVQAANQVQEALDTLMKHLRKDFDKNDKLDNFLLAYENIQEVDDSDDDLDKLVSAARRLAQATTAMISEIQLKAVNEQYKTPEERDRLINAAKQLAEATTVLIDSAKNCTMDKDEMNLRYTLREATERFIVVTYTTECATYIQEQVIDHLLVAARKAATTGTHLINTSLSAAKKSRASNFKVCNDGRELSNQISNLIVAIKEARRDPKDHLAQLELIAACRDYIDPSEQLSQSNKYMWPTVSDPSLQTALNQSINQSVIATEELKKCVHQADLMCQHLDLSAALEQLKRLEQNLKSIKNSIERENLIPLPDEKSDESAALLIKSVRRSGSAANQFKNDLESRCVVYEQTNGEDSYQNLENLDAAGQKARELSMALDRLVHAARGVAASIEFENQESENNDKNLEKLAQLQIVNNCLEAVKAARDLVIEAKSSPPDNDQMDRAQQASVRLSDALSLCLDSLPGQRDLDMLSKHIESKKHQFAENRLPIQQNNNINLSNCRSELTDTTFDFNQAVNELVSAPSFNLVNKGCKKMRMSYDRIVEICNVLVHDPFDESDSALHHLSSNRDHIANGVMIMSEDCQTLLDKVKKIQCEPDNIIVRKQLQEATKMLLDSINRLLTNISTNLRPGQKECDKTIYRLESMRPILDNPVHPISHKDYFECLDFIIDKTVQPLADSLKNIPAAVKDENNQKFIDSIYHCADSVCMLLEETAQTAYLVGVGDVRSKIGNKGLADHTSFLQIQKEISENCQTICNPDTTARQ----MISTAGQIAENSRKLCEASKTIMISFPNDKIKLSDKTKITLLAVSELMTGVQNLNQNFNEDNRKEVESLSGKVQDNVAELVQLLLSYKFAGDAAIISEEAKESQGPIKAAGITVLDTAIEVIQCSKALISSEANEELFIAYSSSCKDLNDALKHLISTIKESAPGQKECDEALAILAKLIKQAYDSKMKIMKHRSRTISRTFESEESYQNILQSALIQMPHCINELSRAGKKEPEQLARIFSRQTQLLESMVNSCICAANQTDLIQNSNIYLEHLIAILEASEQLLKAIKKSGGNPKANSVHSQIDEMAQGVIESCEDLLAALDKISFKQGNVNTIVETITKSSAKVQESAIIPEKSRFGNSQSKMLDICYDMNNLTTDISSNANSESTQRLLAPLTQNLTQRYDDLCRACQGAVATLSNENNGKQLQECVQTVGKVSISLVKSTTEVRPSVASSISNLQAKTQELHKRIDDVIQLLISSNVGTQACTQAIKILKEINSDIDTSILFVKSADIQNDDREYYSVKELFKKSRNSVIDNSSELVRNIKLIVSKDVCDVNILQESADQIAITSQSLANDVKVGLEHLNSSTSQYNIELLVSFQEVIVSLISFLEVARNTSELPYTDPLFQNLKEEGKCSINAITSLLKVLKSMDDVNLKDFQAIDNAIIELEHNHECLLELENGISREASPVESPTSTNRLSIGSDITVSPRFAPEEINRLIPSLANVCDKILEISSPEFKPIIRQENISVVSISCSKVNNELTSACKNLLRNGPVTDSKKQTLNTVDQLVENYTELLKNFKLYLTNPTKETRIPVETVVSKLNELIKLLRDQVNLLREGPRLVMYFRPSSPEWRDVSEKYIGRHVAYHHCFVKSYNHDSHTSLHHHQAPFIQLPINTRYPSEVDLDTAKNQIKFVTTKLIDIKLNPDLIGKDKCSVAEVDQMLSYIKDIGWSTEELLSSSQEICKSNSDTDNEIWNIDFKKEIFKSAIGVSNAMKDLCEAASKPLSTGCSPTWGDRMSTSTRKVANSTGQLLLNLKPTVIQNKSQIEKIHTHGNQIKKNTDLLLNHLNCINDRKWGEASLNAT 2689
BLAST of Talin-1 vs. Planmine SMEST
Match: SMESG000066444.1 (SMESG000066444.1) HSP 1 Score: 5272.98 bits (13677), Expect = 0.000e+0 Identity = 2669/2683 (99.48%), Postives = 2673/2683 (99.63%), Query Frame = 1
Query: 28 MLNSNGNFELRIHIVDADVTKIVPLDPEATIFQLCETIRKNIREAQTKSPKSYGLYLPHDDLKKGLWLDNSKTLQHYILKRGDTIEYRNRSRWLHIRTMDGTNKTLKVDDSWTVSELMLTVCTKLGIYNYDEYSLISDKMDFSPGIDKTLSMKRGISINXXXXXXXXXXXXYHTEDGLNWLNPSQSLRQQGIEESEVLLLKRKYFFSDMNVDSRDPIQLSLLYEQLKDAVINGTHPVTLPEAIELAGLQCQVQLGNYSADKFKPGFLDLRECLPKEYQKNPKTVEKKIFNQHSKSKDLSEVEAKEKYCLLCRSFKTYGITFFLVKEKVIGKNKLIPRLLGVNKESVVQVDEKTKEIINTWPLTSIRKWAASFNGFTMDFGEYSPDEYYTAQTDKGERISQLIAGYIDIILKRKKAKDHLGVDADEESIMYEENIAPSKAIIVEHVPKQKRSSVSEEDVVIRKKAHMANSSVRMNSQASDSVCSQDCTDFYQEDINMSRQTSSLGRTQSPSSSLTTNSMHYRMSDDDIRQKLYIISLQDNLDTIQKYKDQLMIENKGPEIGKDEASQQWIYVNIDNSRQRMADEIGAMNAAVAQVLRSAQGLATIXXXXXXXXXXXXIAKMQNSFSLITVHLPSLMEEIRTAAYYQDQLTDEDVSGEELIAAAKRLADAFTNLIKAAYPVEDQKRSLNRKEIFDAANAVGEASSDLLQQITEQENCQIELKSERPYSIIMITEEDQLYQEELLRLAKSVANETTNLIKQVKVIAVEAENPSDQKKVVMAATETGLAISQLISTTKIVAPTIEQSVCQEQLIFSIEDVSKAIQVVVESSNKATQSEELQDLTVQAANQVQEALDTLMKHLRXXXXXXXXXXXXXXAYENIQEXXXXXXXXXXXXXXXRRLAQATTAMISEIQLKAVNEQYKTPEERDKLINAAKQLAEATTVLIDSAKNCTMDKDEMNLRYTLREATERFIVVTYTTECATYIQEQVIDHLLVAARKAATTGTHLINTSLSAAKKSRASNFKVCNDGRELSNQISNLIVAIKEARRDPKDHLAQLELIAACRDYIDPSEQLSQSNKYMWPTVSDPSLQTALNQSINQSVIATEELKKCVHQADLMCQHLDLSAALEQLKRLEQNLKSIKNSIERENLIPLPDEKSDESAALLIKSVRRSGSAANQFKNDLESRCVVYEQTNGEDSYQNLENLDVAGQKARELSMALDRLVHAARGVAASIEFENQESENNDKNLEKLAQLQIVNNCLEAVKAARDLVIEAKSSPPDNDQMDRAQQASVRXXXXXXXXXXXXPGQRDLDMLSKHIESKKHQFAENRLPIQQNNNINLSNCRSELTDTTFDFNQAVNELVSAPSFNLVNKGCKKMRMSYDRIVEICNVLVHDPFDESDSALHHLSSNRDHIANGVMIMSEDCQTLLDKVKKIQCEPDNIIVRKQLQEATKMLLDSINRLLTNISTNLRPGQKECDKTIYRLESMRPILDNPVHPISHKDYFECLDFIIDKTVQPLADSLKNIPAAVKDENNQKFIDSIYHCADSVCMLLEETAQTAYLVGVGDVRSKIGNKGLADHTSFLQIQKEISENCQTICNPDTTARQDSSLMISTAGQIAENSRKLCEASKTIMISFPNDKIKLSDKTKITLLAVSELMTGVQNLNQNFNEDNRKEVESLSGKVQDNVAELVQLLLSYKFAGDAAIISEEAKESQGPIKAAGITVLDTAIEVIQCSKALISSEANEELFIAYSSSCKDLNDALKHLISTIKESAPGQKECDEXXXXXXXXXXQAYDSKMKIMKHRSRTISRTFESEESYQNILQSALIQMPHCINELSRAGKKEPEQLARIFSRQTQLLESMVNSCICAANQTDLIQNSNIYLEHLITILEASEQLLKAVKKSGGNPKANSVHSQIDEMAQGVIESCEDLLAALDKISFKQGNVNTIVETITKSSAKVQESAIIPEKSRFGNSQSKMLDICYDMNNLTTDISSNANSESTQRLLAPLTQNLTQRYDDLCRACQGAVATLSNENNGKQLQECVQTVGKVSISLVKSTTEVRPSVASSISNLQAKTQELHKRIDDVIQLLISSNVGTQACTQAIKILKEINSDIDTSILFVKSADIQNDDREYYSVKELFKKSRNSVIDNSSELVRNIKLIVSKDVCDVNILQESADQIAITSQSLANDVKVGLEHLNSSTSQYNIELLVSFQEVIVSLISFLEVARNTSGLPYTDPLFQNLKEEGKCSINAITSLLKVLKSMDDVNLKDFQAIDNAIIXXXXXXXXXXXXXXGISREASPVESPTSTNRLSIGSDITVSPRFAPEEINRLIPSLANVCDKILEISSPEFKPIIRQENISVVSISCSKVNNELTSACKNLLRNGPVTDSKKQTLNTVDQLVENYTELLKNFKLYLTNPTKETRIPVETVVSKLNELIKLLRDQVNLLREGPRLVMYFRPSSPEWRDVSEKYIGRHVAYHHCFVKSYNHDSHTSLHHHQAPFIQLPINTRDPSEVDLDTAKNQIKFVTTKLIDIKLNPDLIGKDKCSVAEVDQMLSYIKDIGWSTEELLSSSQEICKSNSDTDNEIWNIDFKKEIFKSAIGVSNAMKDLCEAASKPLSTGCSPTWGDRMSTSTRKVANSTGQLLLNLKPTVIQNKSQIEKIHTHGNQIKKNTDLLLNHLNCINDRKWGEASLNAS 8076
MLNSNGNFELRIHIVDADVTKIVPLDPEATIFQLCETIRKNIREAQTKSPKSYGLYLPHDDLKKGLWLDNSKTLQHYILKRGDTIEYRNRSRWLHIRTMDGTNKTLKVDDSWTVSELMLTVCTKLGIYNYDEYSLISDKMDFSPGIDKTLSMK GISINKDQEKLDKLKKKYHTEDGLNWLNPSQSLRQQGIEESEVLLLKRKYFFSDMNVDSRDPIQLSLLYEQLKDAVINGTHPVTLPEAIELAGLQCQVQLGNYSADKFKPGFLDLRECLPKEYQKNPKTVEKKIFNQHSKSKDLSEVEAKEKYCLLCRSFKTYGITFFLVKEKVIGKNKLIPRLLGVNKESVVQVDEKTKEIINTWPLTSIRKWAASFNGFTMDFGEYSPDEYYTAQTDKGERISQLIAGYIDIILKRKKAKDHLGVDADEESIMYEENIAPSKAIIVEHVPKQKRSSVSEEDVVIRKKAHMANSSVRMNSQASDSVCSQD TDFYQEDINMSRQTSSLGRTQSPSSSLTTNSMHYRMSDDDIRQKLYIISLQDNLDTIQKYKDQLMIENKGPEIGKDEASQQWIYVNIDNSRQRMADEIGAMNAAVAQVLRSAQGLATIEE+EEEEMNEEMIAKMQNSFSLITVHLPSLMEEIRTAAYYQDQLTDEDVSGEELIAAAKRLADAFTNLIKAAYPVEDQKRSLNRKEIFDAANAVGEASSDLLQQITEQENCQIELKSERPYSIIMITEEDQLYQEELLRLAKSVANETTNLIKQVKVIAVEAENPSDQKKVVMAATETGLAISQLISTTKIVAPTIEQSVCQEQLIFSIEDVSKAIQVVVESSNKATQSEELQDLTVQAANQVQEALDTLMKHLRKDFDKNDKLDNFLLAYENIQEVDDSDDDLDKLVSAARRLAQATTAMISEIQLKAVNEQYKTPEERD+LINAAKQLAEATTVLIDSAKNCTMDKDEMNLRYTLREATERFIVVTYTTECATYIQEQVIDHLLVAARKAATTGTHLINTSLSAAKKSRASNFKVCNDGRELSNQISNLIVAIKEARRDPKDHLAQLELIAACRDYIDPSEQLSQSNKYMWPTVSDPSLQTALNQSINQSVIATEELKKCVHQADLMCQHLDLSAALEQLKRLEQNLKSIKNSIERENLIPLPDEKSDESAALLIKSVRRSGSAANQFKNDLESRCVVYEQTNGEDSYQNLENLD AGQKARELSMALDRLVHAARGVAASIEFENQESENNDKNLEKLAQLQIVNNCLEAVKAARDLVIEAKSSPPDNDQMDRAQQASVRLSDALSLCLDSLPGQRDLDMLSKHIESKKHQFAENRLPIQQNNNINLSNCRSELTDTTFDFNQAVNELVSAPSFNLVNKGCKKMRMSYDRIVEICNVLVHDPFDESDSALHHLSSNRDHIANGVMIMSEDCQTLLDKVKKIQCEPDNIIVRKQLQEATKMLLDSINRLLTNISTNLRPGQKECDKTIYRLESMRPILDNPVHPISHKDYFECLDFIIDKTVQPLADSLKNIPAAVKDENNQKFIDSIYHCADSVCMLLEETAQTAYLVGVGDVRSKIGNKGLADHTSFLQIQKEISENCQTICNPDTTARQ MISTAGQIAENSRKLCEASKTIMISFPNDKIKLSDKTKITLLAVSELMTGVQNLNQNFNEDNRKEVESLSGKVQDNVAELVQLLLSYKFAGDAAIISEEAKESQGPIKAAGITVLDTAIEVIQCSKALISSEANEELFIAYSSSCKDLNDALKHLISTIKESAPGQKECDEALAILAKLIKQAYDSKMKIMKHRSRTISRTFESEESYQNILQSALIQMPHCINELSRAGKKEPEQLARIFSRQTQLLESMVNSCICAANQTDLIQNSNIYLEHLI ILEASEQLLKA+KKSGGNPKANSVHSQIDEMAQGVIESCEDLLAALDKISFKQGNVNTIVETITKSSAKVQESAIIPEKSRFGNSQSKMLDICYDMNNLTTDISSNANSESTQRLLAPLTQNLTQRYDDLCRACQGAVATLSNENNGKQLQECVQTVGKVSISLVKSTTEVRPSVASSISNLQAKTQELHKRIDDVIQLLISSNVGTQACTQAIKILKEINSDIDTSILFVKSADIQNDDREYYSVKELFKKSRNSVIDNSSELVRNIKLIVSKDVCDVNILQESADQIAITSQSLANDVKVGLEHLNSSTSQYNIELLVSFQEVIVSLISFLEVARNTS LPYTDPLFQNLKEEGKCSINAITSLLKVLKSMDDVNLKDFQAIDNAIIELEHNHECLLELENGISREASPVESPTSTNRLSIGSDITVSPRFAPEEINRLIPSLANVCDKILEISSPEFKPIIRQENISVVSISCSKVNNELTSACKNLLRNGPVTDSKKQTLNTVDQLVENYTELLKNFKLYLTNPTKETRIPVETVVSKLNELIKLLRDQVNLLREGPRLVMYFRPSSPEWRDVSEKYIGRHVAYHHCFVKSYNHDSHTSLHHHQAPFIQLPINTR PSEVDLDTAKNQIKFVTTKLIDIKLNPDLIGKDKCSVAEVDQMLSYIKDIGWSTEELLSSSQEICKSNSDTDNEIWNIDFKKEIFKSAIGVSNAMKDLCEAASKPLSTGCSPTWGDRMSTSTRKVANSTGQLLLNLKPTVIQNKSQIEKIHTHGNQIKKNTDLLLNHLNCINDRKWGEASLNA+
Sbjct: 1 MLNSNGNFELRIHIVDADVTKIVPLDPEATIFQLCETIRKNIREAQTKSPKSYGLYLPHDDLKKGLWLDNSKTLQHYILKRGDTIEYRNRSRWLHIRTMDGTNKTLKVDDSWTVSELMLTVCTKLGIYNYDEYSLISDKMDFSPGIDKTLSMKHGISINKDQEKLDKLKKKYHTEDGLNWLNPSQSLRQQGIEESEVLLLKRKYFFSDMNVDSRDPIQLSLLYEQLKDAVINGTHPVTLPEAIELAGLQCQVQLGNYSADKFKPGFLDLRECLPKEYQKNPKTVEKKIFNQHSKSKDLSEVEAKEKYCLLCRSFKTYGITFFLVKEKVIGKNKLIPRLLGVNKESVVQVDEKTKEIINTWPLTSIRKWAASFNGFTMDFGEYSPDEYYTAQTDKGERISQLIAGYIDIILKRKKAKDHLGVDADEESIMYEENIAPSKAIIVEHVPKQKRSSVSEEDVVIRKKAHMANSSVRMNSQASDSVCSQDGTDFYQEDINMSRQTSSLGRTQSPSSSLTTNSMHYRMSDDDIRQKLYIISLQDNLDTIQKYKDQLMIENKGPEIGKDEASQQWIYVNIDNSRQRMADEIGAMNAAVAQVLRSAQGLATIEENEEEEMNEEMIAKMQNSFSLITVHLPSLMEEIRTAAYYQDQLTDEDVSGEELIAAAKRLADAFTNLIKAAYPVEDQKRSLNRKEIFDAANAVGEASSDLLQQITEQENCQIELKSERPYSIIMITEEDQLYQEELLRLAKSVANETTNLIKQVKVIAVEAENPSDQKKVVMAATETGLAISQLISTTKIVAPTIEQSVCQEQLIFSIEDVSKAIQVVVESSNKATQSEELQDLTVQAANQVQEALDTLMKHLRKDFDKNDKLDNFLLAYENIQEVDDSDDDLDKLVSAARRLAQATTAMISEIQLKAVNEQYKTPEERDRLINAAKQLAEATTVLIDSAKNCTMDKDEMNLRYTLREATERFIVVTYTTECATYIQEQVIDHLLVAARKAATTGTHLINTSLSAAKKSRASNFKVCNDGRELSNQISNLIVAIKEARRDPKDHLAQLELIAACRDYIDPSEQLSQSNKYMWPTVSDPSLQTALNQSINQSVIATEELKKCVHQADLMCQHLDLSAALEQLKRLEQNLKSIKNSIERENLIPLPDEKSDESAALLIKSVRRSGSAANQFKNDLESRCVVYEQTNGEDSYQNLENLDAAGQKARELSMALDRLVHAARGVAASIEFENQESENNDKNLEKLAQLQIVNNCLEAVKAARDLVIEAKSSPPDNDQMDRAQQASVRLSDALSLCLDSLPGQRDLDMLSKHIESKKHQFAENRLPIQQNNNINLSNCRSELTDTTFDFNQAVNELVSAPSFNLVNKGCKKMRMSYDRIVEICNVLVHDPFDESDSALHHLSSNRDHIANGVMIMSEDCQTLLDKVKKIQCEPDNIIVRKQLQEATKMLLDSINRLLTNISTNLRPGQKECDKTIYRLESMRPILDNPVHPISHKDYFECLDFIIDKTVQPLADSLKNIPAAVKDENNQKFIDSIYHCADSVCMLLEETAQTAYLVGVGDVRSKIGNKGLADHTSFLQIQKEISENCQTICNPDTTARQ----MISTAGQIAENSRKLCEASKTIMISFPNDKIKLSDKTKITLLAVSELMTGVQNLNQNFNEDNRKEVESLSGKVQDNVAELVQLLLSYKFAGDAAIISEEAKESQGPIKAAGITVLDTAIEVIQCSKALISSEANEELFIAYSSSCKDLNDALKHLISTIKESAPGQKECDEALAILAKLIKQAYDSKMKIMKHRSRTISRTFESEESYQNILQSALIQMPHCINELSRAGKKEPEQLARIFSRQTQLLESMVNSCICAANQTDLIQNSNIYLEHLIAILEASEQLLKAIKKSGGNPKANSVHSQIDEMAQGVIESCEDLLAALDKISFKQGNVNTIVETITKSSAKVQESAIIPEKSRFGNSQSKMLDICYDMNNLTTDISSNANSESTQRLLAPLTQNLTQRYDDLCRACQGAVATLSNENNGKQLQECVQTVGKVSISLVKSTTEVRPSVASSISNLQAKTQELHKRIDDVIQLLISSNVGTQACTQAIKILKEINSDIDTSILFVKSADIQNDDREYYSVKELFKKSRNSVIDNSSELVRNIKLIVSKDVCDVNILQESADQIAITSQSLANDVKVGLEHLNSSTSQYNIELLVSFQEVIVSLISFLEVARNTSELPYTDPLFQNLKEEGKCSINAITSLLKVLKSMDDVNLKDFQAIDNAIIELEHNHECLLELENGISREASPVESPTSTNRLSIGSDITVSPRFAPEEINRLIPSLANVCDKILEISSPEFKPIIRQENISVVSISCSKVNNELTSACKNLLRNGPVTDSKKQTLNTVDQLVENYTELLKNFKLYLTNPTKETRIPVETVVSKLNELIKLLRDQVNLLREGPRLVMYFRPSSPEWRDVSEKYIGRHVAYHHCFVKSYNHDSHTSLHHHQAPFIQLPINTRYPSEVDLDTAKNQIKFVTTKLIDIKLNPDLIGKDKCSVAEVDQMLSYIKDIGWSTEELLSSSQEICKSNSDTDNEIWNIDFKKEIFKSAIGVSNAMKDLCEAASKPLSTGCSPTWGDRMSTSTRKVANSTGQLLLNLKPTVIQNKSQIEKIHTHGNQIKKNTDLLLNHLNCINDRKWGEASLNAT 2679
BLAST of Talin-1 vs. Planmine SMEST
Match: SMESG000066444.1 (SMESG000066444.1) HSP 1 Score: 5250.64 bits (13619), Expect = 0.000e+0 Identity = 2671/2726 (97.98%), Postives = 2674/2726 (98.09%), Query Frame = 1
Query: 22 SPMLNSNGNFELRIHIVDADVTKIVPLDPEATIFQLCETIRKNIREAQTKSPKSYGLYLPHDDLKKGLWLDNSKTLQHYILKRGDTIEYRNRSRWLHIRTMDGTNKTLKVDDSWTVSELMLTVCTKLGIYNYDEYSLISDKMDFSPGIDKTLSMKRGISINXXXXXXXXXXXXYHTEDGLNWLNPSQSLRQQGIEESEVLLLKRKYFFSDMNVDSRDPIQLSLLYEQLKDAVINGTHPVTLPEAIELAGLQCQVQLGNYSADKFKPGFLDLRECLPKEYQKNPKTVEKKIFNQHSKSKDLSEVEAKEKYCLLCRSFKTYGITFFLVKEKVIGKNKLIPRLLGVNKESVVQVDEKTKEIINTWPLTSIRKWAASFNGFTMDFGEYSPDEYYTAQTDKGERISQLIAGYIDIILKRKKAKDHLGVDADEESIMYEENIAPSKAIIVEHVPKQKRSSVSEEDVVIRKKAHMANSSVRMNSQASDSVCSQDCTDFYQEDINMSRQTSSLGRTQSPSSSLTTNSMHYRMSDDDIRQKLYIISLQDNLDTIQKYKDQLMIENKGPEIGKDEASQQWIYVNIDNSRQRMADEIGAMNAAVAQVLRSAQGLATIXXXXXXXXXXXXIAKMQNSFSLITVHLPSLMEEIRTAAYYQDQLTDEDVSGEELIAAAKRLADAFTNLIKAAYPVEDQKRSLNRKEIFDAANAVGEASSDLLQQITEQENCQIELKSERPYSIIMITEEDQLYQEELLRLAKSVANETTNLIKQVKVIAVEAENPSDQKKVVMAATETGLAISQLISTTKIVAPTIEQSVCQEQLIFSIEDVSKAIQVVVESSNKATQSEELQDLTVQAANQVQEALDTLMKHLRXXXXXXXXXXXXXXAYENIQEXXXXXXXXXXXXXXXRRLAQATTAMISEIQLKAVNEQYKTPEERDKLINAAKQLAEATTVLIDSAKNCTMDKDEMNLRYTLREATERFIVVTYTTECATYIQEQVIDHLLVAARKAATTGTHLINTSLSAAKKSRASNFKVCNDGRELSNQISNLIVAIKEARRDPKDHLAQLELIAACRDYIDPSEQLSQSNKYMWPTVSDPSLQTALNQSINQSVIATEELKKCVHQADLMCQHLDLSAALEQLKRLEQNLKSIKNSIERENLIPLPDEKSDESAALLIKSVRRSGSAANQFKNDLESRCVVYEQTNGEDSYQNLENLDVAGQKARELSMALDRLVHAARGVAASIEFENQESENNDKNLEKLAQLQIVNNCLEAVKAARDLVIEAKSSPPDNDQMDRAQQASVRXXXXXXXXXXXXPGQRDLDMLSKHIESKKHQFAENRLPIQQNNNINLSNCRSELTDTTFDFNQAVNELVSAPSFNLVNKGCKKMRMSYDRIVEICNVLVHDPFDESDSALHHLSSNRDHIANGVMIMSEDCQTLLDKVKKIQCEPDNIIVRKQLQEATKMLLDSINRLLTNISTNLRPGQKECDKTIYRLESMRPILDNPVHPISHKDYFECLDFIIDKTVQPLADSLKNIPAAVKDENNQKFIDSIYHCADSVCMLLEETAQTAYLVGVGDVRSKIGNKGLADHTSFLQIQKEISENCQTICNPDTTARQDSSLMISTAGQIAENSRKLCEASKTIMISFPNDKIKLSDKTKITLLAVSELMTGVQNLNQNFNEDNRKEVESLSGKVQDNVAELVQLLLSYKFAGDAAIISEEAKESQGPIKAAGITVLDTAIEVIQCSKALISSEANEELFIAYSSSCKDLNDALKHLISTIKESAPGQKECDEXXXXXXXXXXQAYDSKMKIMKHRSRTISRTFESEESYQNILQSALIQMPHCINELSRAGKKEPEQLARIFSRQTQLLESMVNSCICAANQTDLIQNSNIYLEHLITILEASEQLLKAVKKSGGNPKANSVHSQIDEMAQGVIESCEDLLAALDKISFKQGNVNTIVETITKSSAKVQESAIIPEKSRFGNSQSKMLDICYDMNNLTTDISSNANSESTQRLLAPLTQNLTQRYDDLCRACQGAVATLSNENNGKQLQECVQTVGKVSISLVKSTTEVRPSVASSISNLQAKTQELHKRIDDVIQLLISSNVGTQACTQAIKILKEINSDIDTSILFVKSADIQNDDREYYSVKELFKKSRNSVIDNSSELVRNIKLIVSKDVCDVNILQESADQIAITSQSLANDVKVGLEHLNSSTSQYNIELLVSFQEVIVSLISFLEVARNTSGLPYTDPLFQNLKEEGKCSINAITSLLKVLKSMDDVNLKDFQAIDNAIIXXXXXXXXXXXXXXGISREASPVESPTSTNRLSIGSDITVSPRFAPEEINRLIPSLANVCDKILEISSPEFKPIIRQENISVVSISCSKVNNELTSACKNLLRNGPVTDSKKQTLNTVDQLVENYTELLKNFKLYLTNPTKETRIPVETVVSKLNELIKLLRDQVNLLREGPRLVMYFRPSSPEWRDVSEKYIGRHVAYHHCFVKSYNHDSHTSLHHHQAPFIQLPINTRDPSEVDLDTAKNQIKFVTTKLIDIKLNPD------------------------------------------LIGKDKCSVAEVDQMLSYIKDIGWSTEELLSSSQEICKSNSDTDNEIWNIDFKKEIFKSAIGVSNAMKDLCEAASKPLSTGCSPTWGDRMSTSTRKVANSTGQLLLNLKPTVIQNKSQIEKIHTHGNQIKKNTDLLLNHLNCINDRKWGEASLNA 8073
SPMLNSNGNFELRIHIVDADVTKIVPLDPEATIFQLCETIRKNIREAQTKSPKSYGLYLPHDDLKKGLWLDNSKTLQHYILKRGDTIEYRNRSRWLHIRTMDGTNKTLKVDDSWTVSELMLTVCTKLGIYNYDEYSLISDKMDFSPGIDKTLSMK GISINKDQEKLDKLKKKYHTEDGLNWLNPSQSLRQQGIEESEVLLLKRKYFFSDMNVDSRDPIQLSLLYEQLKDAVINGTHPVTLPEAIELAGLQCQVQLGNYSADKFKPGFLDLRECLPKEYQKNPKTVEKKIFNQHSKSKDLSEVEAKEKYCLLCRSFKTYGITFFLVKEKVIGKNKLIPRLLGVNKESVVQVDEKTKEIINTWPLTSIRKWAASFNGFTMDFGEYSPDEYYTAQTDKGERISQLIAGYIDIILKRKKAKDHLGVDADEESIMYEENIAPSKAIIVEHVPKQKRSSVSEEDVVIRKKAHMANSSVRMNSQASDSVCSQD TDFYQEDINMSRQTSSLGRTQSPSSSLTTNSMHYRMSDDDIRQKLYIISLQDNLDTIQKYKDQLMIENKGPEIGKDEASQQWIYVNIDNSRQRMADEIGAMNAAVAQVLRSAQGLATIEE+EEEEMNEEMIAKMQNSFSLITVHLPSLMEEIRTAAYYQDQLTDEDVSGEELIAAAKRLADAFTNLIKAAYPVEDQKRSLNRKEIFDAANAVGEASSDLLQQITEQENCQIELKSERPYSIIMITEEDQLYQEELLRLAKSVANETTNLIKQVKVIAVEAENPSDQKKVVMAATETGLAISQLISTTKIVAPTIEQSVCQEQLIFSIEDVSKAIQVVVESSNKATQSEELQDLTVQAANQVQEALDTLMKHLRKDFDKNDKLDNFLLAYENIQEVDDSDDDLDKLVSAARRLAQATTAMISEIQLKAVNEQYKTPEERD+LINAAKQLAEATTVLIDSAKNCTMDKDEMNLRYTLREATERFIVVTYTTECATYIQEQVIDHLLVAARKAATTGTHLINTSLSAAKKSRASNFKVCNDGRELSNQISNLIVAIKEARRDPKDHLAQLELIAACRDYIDPSEQLSQSNKYMWPTVSDPSLQTALNQSINQSVIATEELKKCVHQADLMCQHLDLSAALEQLKRLEQNLKSIKNSIERENLIPLPDEKSDESAALLIKSVRRSGSAANQFKNDLESRCVVYEQTNGEDSYQNLENLD AGQKARELSMALDRLVHAARGVAASIEFENQESENNDKNLEKLAQLQIVNNCLEAVKAARDLVIEAKSSPPDNDQMDRAQQASVRLSDALSLCLDSLPGQRDLDMLSKHIESKKHQFAENRLPIQQNNNINLSNCRSELTDTTFDFNQAVNELVSAPSFNLVNKGCKKMRMSYDRIVEICNVLVHDPFDESDSALHHLSSNRDHIANGVMIMSEDCQTLLDKVKKIQCEPDNIIVRKQLQEATKMLLDSINRLLTNISTNLRPGQKECDKTIYRLESMRPILDNPVHPISHKDYFECLDFIIDKTVQPLADSLKNIPAAVKDENNQKFIDSIYHCADSVCMLLEETAQTAYLVGVGDVRSKIGNKGLADHTSFLQIQKEISENCQTICNPDTTARQ MISTAGQIAENSRKLCEASKTIMISFPNDKIKLSDKTKITLLAVSELMTGVQNLNQNFNEDNRKEVESLSGKVQDNVAELVQLLLSYKFAGDAAIISEEAKESQGPIKAAGITVLDTAIEVIQCSKALISSEANEELFIAYSSSCKDLNDALKHLISTIKESAPGQKECDEALAILAKLIKQAYDSKMKIMKHRSRTISRTFESEESYQNILQSALIQMPHCINELSRAGKKEPEQLARIFSRQTQLLESMVNSCICAANQTDLIQNSNIYLEHLI ILEASEQLLKA+KKSGGNPKANSVHSQIDEMAQGVIESCEDLLAALDKISFKQGNVNTIVETITKSSAKVQESAIIPEKSRFGNSQSKMLDICYDMNNLTTDISSNANSESTQRLLAPLTQNLTQRYDDLCRACQGAVATLSNENNGKQLQECVQTVGKVSISLVKSTTEVRPSVASSISNLQAKTQELHKRIDDVIQLLISSNVGTQACTQAIKILKEINSDIDTSILFVKSADIQNDDREYYSVKELFKKSRNSVIDNSSELVRNIKLIVSKDVCDVNILQESADQIAITSQSLANDVKVGLEHLNSSTSQYNIELLVSFQEVIVSLISFLEVARNTS LPYTDPLFQNLKEEGKCSINAITSLLKVLKSMDDVNLKDFQAIDNAIIELEHNHECLLELENGISREASPVESPTSTNRLSIGSDITVSPRFAPEEINRLIPSLANVCDKILEISSPEFKPIIRQENISVVSISCSKVNNELTSACKNLLRNGPVTDSKKQTLNTVDQLVENYTELLKNFKLYLTNPTKETRIPVETVVSKLNELIKLLRDQVNLLREGPRLVMYFRPSSPEWRDVSEKYIGRHVAYHHCFVKSYNHDSHTSLHHHQAPFIQLPINTR PSEVDLDTAKNQIKFVTTKLIDIKLNPD LIGKDKCSVAEVDQMLSYIKDIGWSTEELLSSSQEICKSNSDTDNEIWNIDFKKEIFKSAIGVSNAMKDLCEAASKPLSTGCSPTWGDRMSTSTRKVANSTGQLLLNLKPTVIQNKSQIEKIHTHGNQIKKNTDLLLNHLNCINDRKWGEASLNA
Sbjct: 9 SPMLNSNGNFELRIHIVDADVTKIVPLDPEATIFQLCETIRKNIREAQTKSPKSYGLYLPHDDLKKGLWLDNSKTLQHYILKRGDTIEYRNRSRWLHIRTMDGTNKTLKVDDSWTVSELMLTVCTKLGIYNYDEYSLISDKMDFSPGIDKTLSMKHGISINKDQEKLDKLKKKYHTEDGLNWLNPSQSLRQQGIEESEVLLLKRKYFFSDMNVDSRDPIQLSLLYEQLKDAVINGTHPVTLPEAIELAGLQCQVQLGNYSADKFKPGFLDLRECLPKEYQKNPKTVEKKIFNQHSKSKDLSEVEAKEKYCLLCRSFKTYGITFFLVKEKVIGKNKLIPRLLGVNKESVVQVDEKTKEIINTWPLTSIRKWAASFNGFTMDFGEYSPDEYYTAQTDKGERISQLIAGYIDIILKRKKAKDHLGVDADEESIMYEENIAPSKAIIVEHVPKQKRSSVSEEDVVIRKKAHMANSSVRMNSQASDSVCSQDGTDFYQEDINMSRQTSSLGRTQSPSSSLTTNSMHYRMSDDDIRQKLYIISLQDNLDTIQKYKDQLMIENKGPEIGKDEASQQWIYVNIDNSRQRMADEIGAMNAAVAQVLRSAQGLATIEENEEEEMNEEMIAKMQNSFSLITVHLPSLMEEIRTAAYYQDQLTDEDVSGEELIAAAKRLADAFTNLIKAAYPVEDQKRSLNRKEIFDAANAVGEASSDLLQQITEQENCQIELKSERPYSIIMITEEDQLYQEELLRLAKSVANETTNLIKQVKVIAVEAENPSDQKKVVMAATETGLAISQLISTTKIVAPTIEQSVCQEQLIFSIEDVSKAIQVVVESSNKATQSEELQDLTVQAANQVQEALDTLMKHLRKDFDKNDKLDNFLLAYENIQEVDDSDDDLDKLVSAARRLAQATTAMISEIQLKAVNEQYKTPEERDRLINAAKQLAEATTVLIDSAKNCTMDKDEMNLRYTLREATERFIVVTYTTECATYIQEQVIDHLLVAARKAATTGTHLINTSLSAAKKSRASNFKVCNDGRELSNQISNLIVAIKEARRDPKDHLAQLELIAACRDYIDPSEQLSQSNKYMWPTVSDPSLQTALNQSINQSVIATEELKKCVHQADLMCQHLDLSAALEQLKRLEQNLKSIKNSIERENLIPLPDEKSDESAALLIKSVRRSGSAANQFKNDLESRCVVYEQTNGEDSYQNLENLDAAGQKARELSMALDRLVHAARGVAASIEFENQESENNDKNLEKLAQLQIVNNCLEAVKAARDLVIEAKSSPPDNDQMDRAQQASVRLSDALSLCLDSLPGQRDLDMLSKHIESKKHQFAENRLPIQQNNNINLSNCRSELTDTTFDFNQAVNELVSAPSFNLVNKGCKKMRMSYDRIVEICNVLVHDPFDESDSALHHLSSNRDHIANGVMIMSEDCQTLLDKVKKIQCEPDNIIVRKQLQEATKMLLDSINRLLTNISTNLRPGQKECDKTIYRLESMRPILDNPVHPISHKDYFECLDFIIDKTVQPLADSLKNIPAAVKDENNQKFIDSIYHCADSVCMLLEETAQTAYLVGVGDVRSKIGNKGLADHTSFLQIQKEISENCQTICNPDTTARQ----MISTAGQIAENSRKLCEASKTIMISFPNDKIKLSDKTKITLLAVSELMTGVQNLNQNFNEDNRKEVESLSGKVQDNVAELVQLLLSYKFAGDAAIISEEAKESQGPIKAAGITVLDTAIEVIQCSKALISSEANEELFIAYSSSCKDLNDALKHLISTIKESAPGQKECDEALAILAKLIKQAYDSKMKIMKHRSRTISRTFESEESYQNILQSALIQMPHCINELSRAGKKEPEQLARIFSRQTQLLESMVNSCICAANQTDLIQNSNIYLEHLIAILEASEQLLKAIKKSGGNPKANSVHSQIDEMAQGVIESCEDLLAALDKISFKQGNVNTIVETITKSSAKVQESAIIPEKSRFGNSQSKMLDICYDMNNLTTDISSNANSESTQRLLAPLTQNLTQRYDDLCRACQGAVATLSNENNGKQLQECVQTVGKVSISLVKSTTEVRPSVASSISNLQAKTQELHKRIDDVIQLLISSNVGTQACTQAIKILKEINSDIDTSILFVKSADIQNDDREYYSVKELFKKSRNSVIDNSSELVRNIKLIVSKDVCDVNILQESADQIAITSQSLANDVKVGLEHLNSSTSQYNIELLVSFQEVIVSLISFLEVARNTSELPYTDPLFQNLKEEGKCSINAITSLLKVLKSMDDVNLKDFQAIDNAIIELEHNHECLLELENGISREASPVESPTSTNRLSIGSDITVSPRFAPEEINRLIPSLANVCDKILEISSPEFKPIIRQENISVVSISCSKVNNELTSACKNLLRNGPVTDSKKQTLNTVDQLVENYTELLKNFKLYLTNPTKETRIPVETVVSKLNELIKLLRDQVNLLREGPRLVMYFRPSSPEWRDVSEKYIGRHVAYHHCFVKSYNHDSHTSLHHHQAPFIQLPINTRYPSEVDLDTAKNQIKFVTTKLIDIKLNPDSTCSFCEPVLVVDGLGNGRTKSAINNNNNNNKTFKIDVDPYQLIGKDKCSVAEVDQMLSYIKDIGWSTEELLSSSQEICKSNSDTDNEIWNIDFKKEIFKSAIGVSNAMKDLCEAASKPLSTGCSPTWGDRMSTSTRKVANSTGQLLLNLKPTVIQNKSQIEKIHTHGNQIKKNTDLLLNHLNCINDRKWGEASLNA 2730
BLAST of Talin-1 vs. Planmine SMEST
Match: SMESG000019748.1 (SMESG000019748.1) HSP 1 Score: 2668.65 bits (6916), Expect = 0.000e+0 Identity = 1527/1556 (98.14%), Postives = 1532/1556 (98.46%), Query Frame = 1
Query: 8227 WSMPLLVLITSFFVEISHYHSXXXXXXXXFHKSSDQGSKLISIIKSFEMQSNHXXXXXXXXXXXXXXQVESVSLKVDVAIQTDSIXXXXXXXXXXVRSRLQVHETNLLQKSLSSCKYPRKEKDDNLKKHVKFDSSIYTQMLDNVVDKYNRDVLIQQAEIINSSFPKSLSFSENLTQIEPDKEDVDESNIDKVTKPETNSDSGSSPRKIIRSKSDTKILSIWWSHIAKYKKDLTFKDNSVTSRPRLSSNISRVSSHGRRSLLFFGPNQPVLTSNSNPLKTVAMEDSKDLKTGSPTNSGKSPSFNTGVHIRAENKRVSDTRRWSLASLPSSGYGTLTPTSSNLSSQYSSKENLIHHKHHSSHQPRSPLCIGNNNTSQSSPFHSSGLVTSITQSSIRTANVAITGKCISGRNSRNHSPNDKISTIGESHRTPTDSTSDAQFASKTLPITIKPRSQSLNPCRSPGAYEQDIFILNHVYKERFPKATIQMMERLSAMLEELENENTVSWEPISRLVHTQIMKHVKDILNMTNLEAITSTYFFELTQNLEKLLKETRLKCPESLARVRPIVQHLLFIIARPARLLECIEFDPKEFYKLLEVAENNLRNVQTDVPKYIISKLGLDKDPYDIGSEELNTSLELNGGSLEIXXXXXXXXXXXXXXXXXLNMSQESNNSLELSFSKSMTPKESDFEDIKLISNGAYGAVHLVREKKTKKRFAMKKIRKDNLLLRNQVEQIFAERDIMTFADSPFVVGLYCTFETRKYLCMIMEYVEGGDVATLIKSIGPLPDELARMYFAETVLALEYLHNFGIVHRDLKPDNLLITLEGHIKLTDFGLSKVGLMNLTTTLLESVLNKDCTMFQDKQVFGTPDYIAPEVILRQGYDKMIDWWAMGIILYEFIVGCTPFYGDSTEELFGNIISGEIEWPQDPDPCVPDNAVNLITELLKRDPLVRLGAEGTHEVKEHEFFSDVDWQGLLRQKALFIPVLDHEDDTSYFDPRTSRYQHESESDDPDPGSGLGSXXXXXXNDETIEHCEXXXXXXXXXXXXXGTVFHAFPSCSPRFSRFVETELCRMSESSSLVFPQDSEDAGKMXXXXXXXXXXXXXXXXXXXXXXXXDDPIKSHGSAAVTIRTGGNXXXXXXXXXXXXXXXXXXXXXXXXXETELPSVIXXXXXXXWRDVGNQTNAVAMADIAVARERCDXXXXXXXXXXXXXXXXXXXXXCHSTLRALKPIRDPISAVSPLARVDXXXXXXXXXXXXXXXXXXXXXHQLTPPPAPAGSHRRSSAPRAQSPLXXXXXXXXXXXTQEPQPPPAIVIHRRSRNFGFVIRAIRVFYGESNVYTLHHLIVGVDPEGSAFQAGLREGDLITHINGVSIVGAYHTEVVSMIIQSGASISLRVIPINKSFIRTDGPWRPAGKMATKHHPRKAQHLRAGKKCCTGHQKPLKAIGXXXXXXXXXXXXXXXXXLSGGGATYFGYSSPSGSAPQIIRRSTEKPLIRQLSEKQQHRMQQSNQAGGPRQPVADTGSTGLITRTRHQHHXXXXXXXXXXXXXXXXXCHQQQQPPSGGTARR 12894
WSMPLLVLITSFFVEISHYHSLLKWLLLLFHKSSDQGSKLISIIKSFEMQSNHLYNWLNDLTNDNDDQVESVSLKVDVAIQTDSIKHCKCHCRRRVRSRLQVHETNLLQKSLSSCKYPRKEKDDNLKKHVKFDSSIYTQMLDNVVDKYNRDVLIQQAEIINSSFPKSLSFSENLTQIEPDKEDVDESNIDKVTKPETNSDSGSSPRKIIRSKSDTKILSIWWSHIAKYKKDLTFKDNSVTSRPRLSSNISRVSSHGRRSLLFFGPNQPVLTSNSNPLKTVAMEDSKDLKTGSPTNSGKSPSF TGVHIRAENKRVSDTRRWSLASLPSSGYGTLTPTSSNLSSQYSSKENLIHHKHHSSHQPRSPLCIGNNNTSQSSPFHSSGLVTSITQSSIRTANVAITGKCISGRNSRNHSPNDKISTIGESHRTPTDSTSDAQFASKTLPITIKPRSQSLNPCRSPGAYEQDIFILNHVYKERFPKATIQMMERLSAMLEELENENTVSWEPISRLVHTQIMKHVKDILNMTNLEAITSTYFFELTQNLEKLLKETRLKC ESLARVRPIVQHLLFIIARPARLLECIEFDPKEFYKLLEVAENNLRNVQTDVPKYIISKLGLDKDPYDIGSEELNTSLELNGGSLEITGCGGGRSRERTESGCELNMSQ+SNNSLELSFSKSMTPKESDFEDIKLISNGAYGAVHLVREKKTKKRFAMKKIRKDNLLLRNQVEQIFAERDIMTFADSPFVVGLYCTFETRKYLCMIMEYVEGGDVATLIKSIGPLPDELARMYFAETVLALEYLHNFGIVHRDLKPDNLLITLEGHIKLTDFGLSKVGLMNLTTTLLESVLNKDCTMFQDKQVFGTPDYIAPEVILRQGYDKMIDWWAMGIILYEFIVGCTPFYGDSTEELFGNIISGEIEWPQDPDPCVPDNAVNLITELLKRDPLVRLGAEGTHEVKEHEFFSDVDWQGLLRQKALFIPVLDHEDDTSYFDPRTSRYQHESESDDPDPGSGLGSAAAAAANDETIEHCESNDDNNYYSQDNNGTVFHAFPSCSPRFSRFVETELCRMSESSSLVFPQDSEDAGKMARSVSAAPSLLSSESSSSCGGAGGDDPIKSHGSAAVTIRTGGNSSTSSSSLELSAHGSLAHHSSDASSETELPSVIGGGGGNNWRDVGNQTNAVAMADIAVARERCD + S + GAGGGAGCHSTLRALKPIRDPISAVSPLARVD +T A AAANVARSASTHQLTPPPAPAGSHRRSSAPRAQSPL GA+GASGGTQEPQPPPAIVIHRRSRNFGFVIRAIRVFYGESNVYTLHHLIVGVDPEGSAFQAGLREGDLITHINGVSIVGAYHTEVVSMIIQSGASISLRVIPINKSFIRTDGPWRPAGKMATKHHPRKAQHLRAGKKCCTGHQKPLKAIGQVPPVPPHRQQHQVKQHLSGGGATYFGYSSPSGSAPQIIRRSTEKPLIRQLSEKQQHRMQQSNQAGG RQPVADTGSTGLITRTRHQHHSNSNSSSPSPVASSSYSCHQQQQPPSGGTARR
Sbjct: 223 WSMPLLVLITSFFVEISHYHSLLKWLLLLFHKSSDQGSKLISIIKSFEMQSNHLYNWLNDLTNDNDDQVESVSLKVDVAIQTDSIKHCKCHCRRRVRSRLQVHETNLLQKSLSSCKYPRKEKDDNLKKHVKFDSSIYTQMLDNVVDKYNRDVLIQQAEIINSSFPKSLSFSENLTQIEPDKEDVDESNIDKVTKPETNSDSGSSPRKIIRSKSDTKILSIWWSHIAKYKKDLTFKDNSVTSRPRLSSNISRVSSHGRRSLLFFGPNQPVLTSNSNPLKTVAMEDSKDLKTGSPTNSGKSPSFTTGVHIRAENKRVSDTRRWSLASLPSSGYGTLTPTSSNLSSQYSSKENLIHHKHHSSHQPRSPLCIGNNNTSQSSPFHSSGLVTSITQSSIRTANVAITGKCISGRNSRNHSPNDKISTIGESHRTPTDSTSDAQFASKTLPITIKPRSQSLNPCRSPGAYEQDIFILNHVYKERFPKATIQMMERLSAMLEELENENTVSWEPISRLVHTQIMKHVKDILNMTNLEAITSTYFFELTQNLEKLLKETRLKCLESLARVRPIVQHLLFIIARPARLLECIEFDPKEFYKLLEVAENNLRNVQTDVPKYIISKLGLDKDPYDIGSEELNTSLELNGGSLEITGCGGGRSRERTESGCELNMSQDSNNSLELSFSKSMTPKESDFEDIKLISNGAYGAVHLVREKKTKKRFAMKKIRKDNLLLRNQVEQIFAERDIMTFADSPFVVGLYCTFETRKYLCMIMEYVEGGDVATLIKSIGPLPDELARMYFAETVLALEYLHNFGIVHRDLKPDNLLITLEGHIKLTDFGLSKVGLMNLTTTLLESVLNKDCTMFQDKQVFGTPDYIAPEVILRQGYDKMIDWWAMGIILYEFIVGCTPFYGDSTEELFGNIISGEIEWPQDPDPCVPDNAVNLITELLKRDPLVRLGAEGTHEVKEHEFFSDVDWQGLLRQKALFIPVLDHEDDTSYFDPRTSRYQHESESDDPDPGSGLGSAAAAAANDETIEHCESNDDNNYYSQDNNGTVFHAFPSCSPRFSRFVETELCRMSESSSLVFPQDSEDAGKMARSVSAAPSLLSSESSSSCGGAGGDDPIKSHGSAAVTIRTGGNSSTSSSSLELSAHGSLAHHSSDASSETELPSVIGGGGGNNWRDVGNQTNAVAMADIAVARERCD---SSPVAMSVASSGAGGGAGCHSTLRALKPIRDPISAVSPLARVD--STATNPAAAAANVARSASTHQLTPPPAPAGSHRRSSAPRAQSPL---GATGASGGTQEPQPPPAIVIHRRSRNFGFVIRAIRVFYGESNVYTLHHLIVGVDPEGSAFQAGLREGDLITHINGVSIVGAYHTEVVSMIIQSGASISLRVIPINKSFIRTDGPWRPAGKMATKHHPRKAQHLRAGKKCCTGHQKPLKAIGQVPPVPPHRQQHQVKQHLSGGGATYFGYSSPSGSAPQIIRRSTEKPLIRQLSEKQQHRMQQSNQAGGSRQPVADTGSTGLITRTRHQHHSNSNSSSPSPVASSSYSCHQQQQPPSGGTARR 1770 The following BLAST results are available for this feature:
BLAST of Talin-1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Talin-1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Talin-1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Talin-1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Talin-1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Talin-1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Talin-1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Talin-1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Talin-1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Talin-1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Talin-1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 5
BLAST of Talin-1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Talin-1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Talin-1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30018086 ID=SMED30018086|Name=Talin-1|organism=Schmidtea mediterranea sexual|type=transcript|length=13480bpback to top protein sequence of SMED30018086-orf-1 >SMED30018086-orf-1 ID=SMED30018086-orf-1|Name=SMED30018086-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=1555bp MPLLVLITSFFVEISHYHSLLKWLLLLFHKSSDQGSKLISIIKSFEMQSNback to top protein sequence of SMED30018086-orf-2 >SMED30018086-orf-2 ID=SMED30018086-orf-2|Name=SMED30018086-orf-2|organism=Schmidtea mediterranea sexual|type=polypeptide|length=2733bp MLNSNGNFELRIHIVDADVTKIVPLDPEATIFQLCETIRKNIREAQTKSPback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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