Glycine receptor subunit alpha-3
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30018078 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 10
Homology
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Human
Match: GLRA3 (glycine receptor alpha 3 [Source:HGNC Symbol;Acc:HGNC:4328]) HSP 1 Score: 259.996 bits (663), Expect = 1.965e-80 Identity = 151/440 (34.32%), Postives = 249/440 (56.59%), Query Frame = 1
Query: 175 RKSPMAQQRDLIMERIVDKKRYKKDERPS-EIYQTNVLVYMKVLAINSVSVTKMEYSTDVYLRQEWTDPRLTWENLEEFRSFNNNIVSPSLKKILWLPDLFFRNGKEGYVHKMTLPNYLMRLRPNGRILYSQKITMRFSCEMNLQTFPMDSQECLMDIGSYGYTLDELKFTWRKEDPILISTGLQISEFNSPHQVSTIDCTNDSSTSTGKYTCLKAKFLLQRQLGSYLVSTFVPSILIVMVSWLNFWINVDSVPARXXXXXXXXXXXXXQATGISSTLPRVSYIKAIDVWVIACIMFVIGALLEYVVASVLARKKKSNGWEKDVREIVRHELAR--WCSACQRQQFFHLQEQNTLDR-NRLEFCSELESLLINHALDAHKGK---------KTIKTTPTE--------DSDIDSYSRFLFPACFLLYNCFYWLYYLVLVH 1431
R +PM+ D + + + Y RP+ + NV + + + S++ T M+Y +++LRQ+W DPRL + + ++ + PS+ +W PDLFF N K H++T N L+R+ NG +LYS ++T+ SC M+L+ FPMD Q C+M + S+GYT+++L F W+ E P+ ++ GL + +F + CT +TGK+TC++ +F L+RQ+G YL+ ++PS+LIV++SW++FWIN+D+ PARV LG+ T+L M TQ++G ++LP+VSY+KAID+W+ C++FV ALLEY + ++R+ K E++R R A ++F+ + + R +R F + + L A G + + +P E ID+ SR FP FL++N FYW+ Y +L H
Sbjct: 37 RSAPMSPS-DFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPD----DSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQDEAPVQVAEGLTLPQFLLKEEKDLRYCTK--HYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHK---------ELLRFRRKRKNKTEAFALEKFYRFSDMDDEVRESRFSFT----AYGMGPCLQAKDGMTPKGPNHPVQVMPKSPDEMRKVFIDRAKKIDTISRACFPLAFLIFNIFYWVIYKILRH 456
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Human
Match: GLRA3 (glycine receptor alpha 3 [Source:HGNC Symbol;Acc:HGNC:4328]) HSP 1 Score: 258.455 bits (659), Expect = 4.724e-80 Identity = 148/429 (34.50%), Postives = 243/429 (56.64%), Query Frame = 1
Query: 175 RKSPMAQQRDLIMERIVDKKRYKKDERPS-EIYQTNVLVYMKVLAINSVSVTKMEYSTDVYLRQEWTDPRLTWENLEEFRSFNNNIVSPSLKKILWLPDLFFRNGKEGYVHKMTLPNYLMRLRPNGRILYSQKITMRFSCEMNLQTFPMDSQECLMDIGSYGYTLDELKFTWRKEDPILISTGLQISEFNSPHQVSTIDCTNDSSTSTGKYTCLKAKFLLQRQLGSYLVSTFVPSILIVMVSWLNFWINVDSVPARXXXXXXXXXXXXXQATGISSTLPRVSYIKAIDVWVIACIMFVIGALLEYVVASVLAR--------KKKSNGWEKDVREIVRHELARWCSAC-QRQQFFHLQEQNTLDRNRLEFCSELESLLINHALDAHKGKKTIKTTPTEDSDIDSYSRFLFPACFLLYNCFYWLYYLVLVH 1431
R +PM+ D + + + Y RP+ + NV + + + S++ T M+Y +++LRQ+W DPRL + + ++ + PS+ +W PDLFF N K H++T N L+R+ NG +LYS ++T+ SC M+L+ FPMD Q C+M + S+GYT+++L F W+ E P+ ++ GL + +F + CT +TGK+TC++ +F L+RQ+G YL+ ++PS+LIV++SW++FWIN+D+ PARV LG+ T+L M TQ++G ++LP+VSY+KAID+W+ C++FV ALLEY + ++R ++K + +VRE A C Q + + N + + E+ + I+ A ID+ SR FP FL++N FYW+ Y +L H
Sbjct: 37 RSAPMSPS-DFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPD----DSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQDEAPVQVAEGLTLPQFLLKEEKDLRYCTK--HYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRKRKNKDDEVRESRFSFTAYGMGPCLQAKDGMTPKGPNHPVQVMPKSPDEMRKVFIDRA-----------------KKIDTISRACFPLAFLIFNIFYWVIYKILRH 441
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Human
Match: GLRA2 (glycine receptor alpha 2 [Source:HGNC Symbol;Acc:HGNC:4327]) HSP 1 Score: 254.603 bits (649), Expect = 1.481e-78 Identity = 145/404 (35.89%), Postives = 229/404 (56.68%), Query Frame = 1
Query: 277 NVLVYMKVLAINSVSVTKMEYSTDVYLRQEWTDPRLTWENLEEFRSFNNNIVSPSLKKILWLPDLFFRNGKEGYVHKMTLPNYLMRLRPNGRILYSQKITMRFSCEMNLQTFPMDSQECLMDIGSYGYTLDELKFTWRKEDPILISTGLQISEFNSPHQVSTIDCTNDSSTSTGKYTCLKAKFLLQRQLGSYLVSTFVPSILIVMVSWLNFWINVDSVPARXXXXXXXXXXXXXQATGISSTLPRVSYIKAIDVWVIACIMFVIGALLEYVVASVLARKKKSNGWEKDVREIVRHELARWCSACQRQQFFHLQEQNTLDRNRLEFCSELESLLINHALDAHKGKKTIKTTPT-------EDSD------------IDSYSRFLFPACFLLYNCFYWLYYLVLVH 1431
NV + + + SV+ T M+Y +++LRQ+W D RL + + ++ + PS+ +W PDLFF N K H +T N L+R+ NG++LYS ++T+ SC M+L+ FPMD Q C M + S+GYT+++L F W + P+ ++ GL + +F + CT +TGK+TC++ KF L+RQ+G YL+ ++PS+LIV++SW++FWIN+D+ PARV LG+ T+L M TQ++G ++LP+VSY+KAID+W+ C++FV ALLEY + ++R+ K E R +RQ +E++ +R F + H L G +K TP +D D ID+ SR FP FL++N FYW+ Y ++ H
Sbjct: 72 NVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPD----DSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWLSDGPVQVAEGLTLPQFILKEEKELGYCTK--HYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQHK--------------EFLRLRRRQKRQN----KEEDVTRESRFNF----SGYGMGHCLQVKDG-TAVKATPANPLPQPPKDGDAIKKKFVDRAKRIDTISRAAFPLAFLIFNIFYWITYKIIRH 446
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Human
Match: GLRA2 (glycine receptor alpha 2 [Source:HGNC Symbol;Acc:HGNC:4327]) HSP 1 Score: 253.832 bits (647), Expect = 3.053e-78 Identity = 144/404 (35.64%), Postives = 229/404 (56.68%), Query Frame = 1
Query: 277 NVLVYMKVLAINSVSVTKMEYSTDVYLRQEWTDPRLTWENLEEFRSFNNNIVSPSLKKILWLPDLFFRNGKEGYVHKMTLPNYLMRLRPNGRILYSQKITMRFSCEMNLQTFPMDSQECLMDIGSYGYTLDELKFTWRKEDPILISTGLQISEFNSPHQVSTIDCTNDSSTSTGKYTCLKAKFLLQRQLGSYLVSTFVPSILIVMVSWLNFWINVDSVPARXXXXXXXXXXXXXQATGISSTLPRVSYIKAIDVWVIACIMFVIGALLEYVVASVLARKKKSNGWEKDVREIVRHELARWCSACQRQQFFHLQEQNTLDRNRLEFCSELESLLINHALDAHKGKKTIKTTPT-------EDSD------------IDSYSRFLFPACFLLYNCFYWLYYLVLVH 1431
NV + + + S++ T M+Y +++LRQ+W D RL + + ++ + PS+ +W PDLFF N K H +T N L+R+ NG++LYS ++T+ SC M+L+ FPMD Q C M + S+GYT+++L F W + P+ ++ GL + +F + CT +TGK+TC++ KF L+RQ+G YL+ ++PS+LIV++SW++FWIN+D+ PARV LG+ T+L M TQ++G ++LP+VSY+KAID+W+ C++FV ALLEY + ++R+ K E R +RQ +E++ +R F + H L G +K TP +D D ID+ SR FP FL++N FYW+ Y ++ H
Sbjct: 72 NVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDSRLAYSEYPD----DSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWLSDGPVQVAEGLTLPQFILKEEKELGYCTK--HYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQHK--------------EFLRLRRRQKRQN----KEEDVTRESRFNF----SGYGMGHCLQVKDG-TAVKATPANPLPQPPKDGDAIKKKFVDRAKRIDTISRAAFPLAFLIFNIFYWITYKIIRH 446
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Human
Match: GLRA1 (glycine receptor alpha 1 [Source:HGNC Symbol;Acc:HGNC:4326]) HSP 1 Score: 252.677 bits (644), Expect = 1.200e-77 Identity = 139/402 (34.58%), Postives = 231/402 (57.46%), Query Frame = 1
Query: 277 NVLVYMKVLAINSVSVTKMEYSTDVYLRQEWTDPRLTWENLEEFRSFNNNIVSPSLKKILWLPDLFFRNGKEGYVHKMTLPNYLMRLRPNGRILYSQKITMRFSCEMNLQTFPMDSQECLMDIGSYGYTLDELKFTWRKEDPILISTGLQISEFNSPHQVSTIDCTNDSSTSTGKYTCLKAKFLLQRQLGSYLVSTFVPSILIVMVSWLNFWINVDSVPARXXXXXXXXXXXXXQATGISSTLPRVSYIKAIDVWVIACIMFVIGALLEYVVASVLARKKKSNGWEKDVREIVRHELARWCSACQRQQFFHLQEQNTLDRNRLEFCSELESLLINHALDA--HKGKKTIKTT-----PTEDSD------------IDSYSRFLFPACFLLYNCFYWLYYLVL 1425
NV + + + S++ T M+Y +++LRQ+W DPRL + + ++ + PS+ +W PDLFF N K + H++T N L+R+ NG +LYS +IT+ +C M+L+ FPMD Q C+M + S+GYT+++L F W+++ + ++ GL + +F + CT +TGK+TC++A+F L+RQ+G YL+ ++PS+LIV++SW++FWIN+D+ PARV LG+ T+L M TQ++G ++LP+VSY+KAID+W+ C++FV ALLEY + ++R+ K + R + + +L +++ R F + A D KG TT P++ + ID SR FP FL++N FYW+ Y ++
Sbjct: 66 NVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYNEYPD----DSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQEQGAVQVADGLTLPQFILKEEKDLRYCTK--HYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWISFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRKRRHHKSPM------------LNLFQEDEAGEGRFNFSAYGMGPACLQAKDGISVKGANNSNTTNPPPAPSKSPEEMRKLFIQRAKKIDKISRIGFPMAFLIFNMFYWIIYKIV 449
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Celegans
Match: avr-14 (pep chromosome:WBcel235:I:5968009:5973320:-1 gene:WBGene00000232.1 transcript:B0207.12a.2 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:avr-14) HSP 1 Score: 227.254 bits (578), Expect = 6.337e-69 Identity = 142/394 (36.04%), Postives = 220/394 (55.84%), Query Frame = 1
Query: 280 VLVYMKVLAINSVSVTKMEYSTDVYLRQEWTDPRLTWENLEEFRSFNNNIVSPSL----------KKILWLPDLFFRNGKEGYVHKMTLPNYLMRLRPNGRILYSQKITMRFSCEMNLQTFPMDSQECLMDIGSYGYTLDELKFTWRKEDPILISTGLQISEFNSPHQ-VSTIDCTNDSSTSTGKYTCLKAKFLLQRQLGSYLVSTFVPSILIVMVSWLNFWINVDSVPARXXXXXXXXXXXXXQATGISSTLPRVSYIKAIDVWVIACIMFVIGALLEYVVASVLARKKKSNGWEKDVREI--VRHELARWCSACQRQQFFHLQEQNTLDRNRLEFCSELESLLINHALDAHKGKKTIKTTPTEDSDIDSYSRFLFPACFLLYNCFYWLYYLV 1422
V V + + +I+ + MEYS R+EWTD RL +E EE + V P + + +W+PD FF+N KE H + PN L+R+ NG+ILYS ++++ SC M+L+ +P+D Q CL+D+ SY YT ++K+ W+++ PI GL+ S + Q V T CT S T+TG+Y+CL+ + +L+R+ YL+ ++PS ++V+VSW++FW++ DSVPARVTLG+ TLL M TQ++GI++ LP VSY KAIDVW+ C+ F+ GALLE+ + + ARK + ++ +R++ + E R SA Q R FC + ++ ID SR +FP + +N YW YL+
Sbjct: 60 VTVNIYLRSISKIDDVNMEYSAQFTFREEWTDQRLAYERYEES---GDTEVPPFVVLATSENADQSQQIWMPDTFFQNEKEARRHLIDKPNVLIRIHKNGQILYSVRLSLVLSCPMSLEFYPLDRQNCLIDLASYAYTTQDIKYEWKEKKPIQQKDGLRQSLPSFELQDVVTDYCT--SLTNTGEYSCLRTRMVLRREFSYYLLQLYIPSFMLVIVSWVSFWLDKDSVPARVTLGVTTLLTMTTQSSGINAKLPPVSYTKAIDVWIGVCLAFIFGALLEFALVNYAARKDMTQVSQR-IRQMKQLPTEGYRPLSASQ---------------GRSSFCCRI----------------FVRRYKERSKRIDVVSRLVFPIGYACFNVLYWAVYLM 416
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Celegans
Match: avr-14 (pep chromosome:WBcel235:I:5967250:5973320:-1 gene:WBGene00000232.1 transcript:B0207.12a.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:avr-14) HSP 1 Score: 227.254 bits (578), Expect = 6.337e-69 Identity = 142/394 (36.04%), Postives = 220/394 (55.84%), Query Frame = 1
Query: 280 VLVYMKVLAINSVSVTKMEYSTDVYLRQEWTDPRLTWENLEEFRSFNNNIVSPSL----------KKILWLPDLFFRNGKEGYVHKMTLPNYLMRLRPNGRILYSQKITMRFSCEMNLQTFPMDSQECLMDIGSYGYTLDELKFTWRKEDPILISTGLQISEFNSPHQ-VSTIDCTNDSSTSTGKYTCLKAKFLLQRQLGSYLVSTFVPSILIVMVSWLNFWINVDSVPARXXXXXXXXXXXXXQATGISSTLPRVSYIKAIDVWVIACIMFVIGALLEYVVASVLARKKKSNGWEKDVREI--VRHELARWCSACQRQQFFHLQEQNTLDRNRLEFCSELESLLINHALDAHKGKKTIKTTPTEDSDIDSYSRFLFPACFLLYNCFYWLYYLV 1422
V V + + +I+ + MEYS R+EWTD RL +E EE + V P + + +W+PD FF+N KE H + PN L+R+ NG+ILYS ++++ SC M+L+ +P+D Q CL+D+ SY YT ++K+ W+++ PI GL+ S + Q V T CT S T+TG+Y+CL+ + +L+R+ YL+ ++PS ++V+VSW++FW++ DSVPARVTLG+ TLL M TQ++GI++ LP VSY KAIDVW+ C+ F+ GALLE+ + + ARK + ++ +R++ + E R SA Q R FC + ++ ID SR +FP + +N YW YL+
Sbjct: 60 VTVNIYLRSISKIDDVNMEYSAQFTFREEWTDQRLAYERYEES---GDTEVPPFVVLATSENADQSQQIWMPDTFFQNEKEARRHLIDKPNVLIRIHKNGQILYSVRLSLVLSCPMSLEFYPLDRQNCLIDLASYAYTTQDIKYEWKEKKPIQQKDGLRQSLPSFELQDVVTDYCT--SLTNTGEYSCLRTRMVLRREFSYYLLQLYIPSFMLVIVSWVSFWLDKDSVPARVTLGVTTLLTMTTQSSGINAKLPPVSYTKAIDVWIGVCLAFIFGALLEFALVNYAARKDMTQVSQR-IRQMKQLPTEGYRPLSASQ---------------GRSSFCCRI----------------FVRRYKERSKRIDVVSRLVFPIGYACFNVLYWAVYLM 416
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Celegans
Match: avr-15 (pep chromosome:WBcel235:V:13498786:13502743:-1 gene:WBGene00000233.1 transcript:R11G10.1b.2 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:avr-15) HSP 1 Score: 223.787 bits (569), Expect = 8.332e-67 Identity = 147/417 (35.25%), Postives = 236/417 (56.59%), Query Frame = 1
Query: 208 IMERIVDKKRYKKDERPSE---IYQTNVLVYMKVL--AINSVSVTKMEYSTDVYLRQEWTDPRLTWENLEEFRSFNNNIVSPSLKKILWLPDLFFRNGKEGYVHKMTLPNYLMRLRPNGRILYSQKITMRFSCEMNLQTFPMDSQECLMDIGSYGYTLDELKFTWRKEDPILISTGLQIS--EFNSPHQVSTIDCTNDSSTSTGKYTCLKAKFLLQRQLGSYLVSTFVPSILIVMVSWLNFWINVDSVPARXXXXXXXXXXXXXQATGISSTLPRVSYIKAIDVWVIACIMFVIGALLEYVVASVLARKKKSNGWEKDVREIVRHELARWCSACQRQQFFHLQEQNT---LDRNRLEFCSELESLLINHALDAHKGKKTIKTTPTEDSD----IDSYSRFLFPACFLLYNCFYWLYY 1416
I+E ++ + + P E I+ V+V + +L +I+ + MEYS + R+ W D RL++ + + + + + + +W+PD FF+N K+ Y H + PN L+R+ +G ILYS +I++ SC M+LQ +PMD Q+C +D+ SY YT ++++ W++E P+ + GL S F + ST CT S T+TG Y+CL+ L+RQ YL+ ++PS ++V+VSW++FWI+ +VPARVTLG+ TLL M TQ++GI++ LP V+YIKAIDVW+ AC+ F+ ALLE+ + +A K+ +N + RE + + LQ + + R E E+ ++ +N + K IKT TE +D D SR +FP FL +N YW +Y
Sbjct: 75 ILEHLLTRGYDHRVRPPGEDGTIHGGPVVVSVNMLLRSISKIDNVNMEYSVQLTFRESWVDKRLSFGVKGDAQP---DFLILTAGQEIWMPDSFFQNEKQAYKHMIDKPNVLIRVHKDGTILYSVRISLVLSCPMHLQYYPMDVQQCFIDLASYAYTTKDIEYVWKEETPVQLKAGLSSSLPSFQLTN-TSTTYCT--SKTNTGSYSCLRTIIQLRRQFSYYLLQLYIPSCMLVIVSWVSFWIDRTAVPARVTLGVTTLLTMTTQSSGINAKLPPVAYIKAIDVWIGACMTFIFCALLEFAWVTYIANKQDANKRARTERE--------------KAELPFLQNSHNDVWVPREVAEQEREVMTVRMNRR-QTNSVWKWIKTK-TEWNDKSKRADLISRVMFPVLFLTFNISYWTHY 469
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Celegans
Match: avr-15 (pep chromosome:WBcel235:V:13498786:13502582:-1 gene:WBGene00000233.1 transcript:R11G10.1b.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:avr-15) HSP 1 Score: 223.787 bits (569), Expect = 8.332e-67 Identity = 147/417 (35.25%), Postives = 236/417 (56.59%), Query Frame = 1
Query: 208 IMERIVDKKRYKKDERPSE---IYQTNVLVYMKVL--AINSVSVTKMEYSTDVYLRQEWTDPRLTWENLEEFRSFNNNIVSPSLKKILWLPDLFFRNGKEGYVHKMTLPNYLMRLRPNGRILYSQKITMRFSCEMNLQTFPMDSQECLMDIGSYGYTLDELKFTWRKEDPILISTGLQIS--EFNSPHQVSTIDCTNDSSTSTGKYTCLKAKFLLQRQLGSYLVSTFVPSILIVMVSWLNFWINVDSVPARXXXXXXXXXXXXXQATGISSTLPRVSYIKAIDVWVIACIMFVIGALLEYVVASVLARKKKSNGWEKDVREIVRHELARWCSACQRQQFFHLQEQNT---LDRNRLEFCSELESLLINHALDAHKGKKTIKTTPTEDSD----IDSYSRFLFPACFLLYNCFYWLYY 1416
I+E ++ + + P E I+ V+V + +L +I+ + MEYS + R+ W D RL++ + + + + + + +W+PD FF+N K+ Y H + PN L+R+ +G ILYS +I++ SC M+LQ +PMD Q+C +D+ SY YT ++++ W++E P+ + GL S F + ST CT S T+TG Y+CL+ L+RQ YL+ ++PS ++V+VSW++FWI+ +VPARVTLG+ TLL M TQ++GI++ LP V+YIKAIDVW+ AC+ F+ ALLE+ + +A K+ +N + RE + + LQ + + R E E+ ++ +N + K IKT TE +D D SR +FP FL +N YW +Y
Sbjct: 75 ILEHLLTRGYDHRVRPPGEDGTIHGGPVVVSVNMLLRSISKIDNVNMEYSVQLTFRESWVDKRLSFGVKGDAQP---DFLILTAGQEIWMPDSFFQNEKQAYKHMIDKPNVLIRVHKDGTILYSVRISLVLSCPMHLQYYPMDVQQCFIDLASYAYTTKDIEYVWKEETPVQLKAGLSSSLPSFQLTN-TSTTYCT--SKTNTGSYSCLRTIIQLRRQFSYYLLQLYIPSCMLVIVSWVSFWIDRTAVPARVTLGVTTLLTMTTQSSGINAKLPPVAYIKAIDVWIGACMTFIFCALLEFAWVTYIANKQDANKRARTERE--------------KAELPFLQNSHNDVWVPREVAEQEREVMTVRMNRR-QTNSVWKWIKTK-TEWNDKSKRADLISRVMFPVLFLTFNISYWTHY 469
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Celegans
Match: glc-2 (Glutamate-gated chloride channel subunit beta [Source:UniProtKB/Swiss-Prot;Acc:Q17328]) HSP 1 Score: 221.861 bits (564), Expect = 1.320e-66 Identity = 134/392 (34.18%), Postives = 212/392 (54.08%), Query Frame = 1
Query: 277 NVLVYMKVLAINSVSVTKMEYSTDVYLRQEWTDPRLTWENLEEFRSFNNNIVSPSLKKILWLPDLFFRNGKEGYVHKMTLPNYLMRLRPNGRILYSQKITMRFSCEMNLQTFPMDSQECLMDIGSYGYTLDELKFTWRKEDPILISTGL--QISEFNSPHQVSTIDCTNDSSTSTGKYTCLKAKFLLQRQLGSYLVSTFVPSILIVMVSWLNFWINVDSVPARXXXXXXXXXXXXXQATGISSTLPRVSYIKAIDVWVIACIMFVIGALLEYVVASVLARKKKSNGWEKDVREIVRHELARWCSACQRQQFFHLQEQNTLDRNRLEFCSE--LESLLINHALDAH-----KGKKTIKTTPTEDSDIDSYSRFLFPACFLLYNCFYWLYYLVL 1425
NV V + + ++ + V MEYS + R++W DPRL +ENL F + + P +KK LW+PD FF K + H + + N +R+ P+G+ILYS +I++ SC M LQ +P+D Q C D+ SY +T++++ + W P+ + G+ + F + + DCT S T+TG Y CL+ + L +RQ YLV + P+ +IV+VSW++FWI++ S RV LG+ TLL M T + I++ LP VSY+K +DVW+ AC FV GALLEY S ++ VR+ ++ +R +A + Q+ R +LE + H +A K ++ + ID Y+RF+ P FL +N YW+ L++
Sbjct: 58 NVRVNIMIRMLSKIDVVNMEYSIQLTFREQWIDPRLAYENLG-FYNPPAFLTVPHVKKSLWIPDTFFPTEKAAHRHLIDMENMFLRIYPDGKILYSSRISLTSSCPMRLQLYPLDYQSCNFDLVSYAHTMNDIMYEWDPSTPVQLKPGVGSDLPNFILKNYTTNADCT--SHTNTGSYGCLRMQLLFKRQFSYYLVQLYAPTTMIVIVSWVSFWIDLHSTAGRVALGVTTLLTMTTMQSAINAKLPPVSYVKVVDVWLGACQTFVFGALLEYAFVS----------YQDSVRQ---NDRSREKAARKAQR----------RREKLEMVDAEVYQPPCTCHTFEARETFRDKVRRYFTKPDYLPAKIDFYARFVVPLAFLAFNVIYWVSCLIM 423
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Fly
Match: GluClalpha (gene:FBgn0024963 transcript:FBtr0335420) HSP 1 Score: 239.195 bits (609), Expect = 6.336e-73 Identity = 144/413 (34.87%), Postives = 228/413 (55.21%), Query Frame = 1
Query: 208 IMERIVDKKRYKKDERPSEI-----YQTNVLVYMKVLAINSVSVTKMEYSTDVYLRQEWTDPRLTWENLEEFRSFNNNIVSPSLKKILWLPDLFFRNGKEGYVHKMTLPNYLMRLRPNGRILYSQKITMRFSCEMNLQTFPMDSQECLMDIGSYGYTLDELKFTWRKEDPILISTGLQISEFNSPHQVSTIDCTNDSSTSTGKYTCLKAKFLLQRQLGSYLVSTFVPSILIVMVSWLNFWINVDSVPARXXXXXXXXXXXXXQATGISSTLPRVSYIKAIDVWVIACIMFVIGALLEYVVASVLARKKKSNGWEKDVREIVRHELARWCSACQRQQFFHLQEQNTLDRNRLEFCSELESLLINHALDAHKGKKTIKT----TPTEDSDIDSYSRFLFPACFLLYNCFYWLYYL 1419
++++I+ +Y RPS I TNV V M + +I+ + KMEYS + R++WTD RL +++++ + ++ + +W+PDLFF N KEG+ H + +PN +R+ PNG +LYS +I++ +C MNL+ +P+D Q C + + SYG+T ++L F W++ DP+ + L + F + + T C +S T+TG+Y+CLK L +R+ YL+ ++P ++V+VSW++FW++ +VPARV+LG+ TLL M TQ +GI+++LP VSY KAIDVW C+ FV GALLE+ + + +R K R + S L R+ + + + L + A K KT PT ID SR FP F L+N YW YL
Sbjct: 36 VLDQILGAGKYDARIRPSGINGTDNKATNVSVNMFLRSISKIDDYKMEYSVQLTFREQWTDERLKFDDIQGRLKY----LTLTEANRVWMPDLFFSNEKEGHFHNIIMPNVYIRIFPNGSVLYSIRISLTLACPMNLKLYPLDRQICSLRMASYGWTTNDLVFLWKEGDPVQVVKNLHLPRF-TLEKFLTDYC--NSKTNTGEYSCLKVDLLFKREFSYYLIQIYIPCCMLVIVSWVSFWLDQGAVPARVSLGVTTLLTMATQTSGINASLPPVSYTKAIDVWTGVCLTFVFGALLEFALVNYASRSDMHKENMKKKRRDLEQASLDAASDLLDTDSNATFAMKPLVRHPGDPLALEKRLQCEVHMQAPKRPNCCKTWLSKFPTRSKRIDVISRITFPLVFALFNLVYWSTYL 441
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Fly
Match: GluClalpha (gene:FBgn0024963 transcript:FBtr0335419) HSP 1 Score: 238.424 bits (607), Expect = 1.165e-72 Identity = 143/412 (34.71%), Postives = 229/412 (55.58%), Query Frame = 1
Query: 208 IMERIVDKKRYKKDERPSEIYQTN----VLVYMKVLAINSVSVTKMEYSTDVYLRQEWTDPRLTWENLEEFRSFNNNIVSPSLKKILWLPDLFFRNGKEGYVHKMTLPNYLMRLRPNGRILYSQKITMRFSCEMNLQTFPMDSQECLMDIGSYGYTLDELKFTWRKEDPILISTGLQISEFNSPHQVSTIDCTNDSSTSTGKYTCLKAKFLLQRQLGSYLVSTFVPSILIVMVSWLNFWINVDSVPARXXXXXXXXXXXXXQATGISSTLPRVSYIKAIDVWVIACIMFVIGALLEYVVASVLARKKKSNGWEKDVREIVRHELARWCSACQRQQFFHLQEQNTLDRNRLEFCSELESLLINHALDAHKGKKTIKT----TPTEDSDIDSYSRFLFPACFLLYNCFYWLYYL 1419
++++I+ +Y RPS I T+ V + + V +I ++S KMEYS + R++WTD RL +++++ + ++ + +W+PDLFF N KEG+ H + +PN +R+ PNG +LYS +I++ +C MNL+ +P+D Q C + + SYG+T ++L F W++ DP+ + L + F + + T C +S T+TG+Y+CLK L +R+ YL+ ++P ++V+VSW++FW++ +VPARV+LG+ TLL M TQ +GI+++LP VSY KAIDVW C+ FV GALLE+ + + +R K R + S L R+ + + + L + A K KT PT ID SR FP F L+N YW YL
Sbjct: 36 VLDQILGAGKYDARIRPSGINGTDGPAIVRINLFVRSIMTISDIKMEYSVQLTFREQWTDERLKFDDIQGRLKY----LTLTEANRVWMPDLFFSNEKEGHFHNIIMPNVYIRIFPNGSVLYSIRISLTLACPMNLKLYPLDRQICSLRMASYGWTTNDLVFLWKEGDPVQVVKNLHLPRF-TLEKFLTDYC--NSKTNTGEYSCLKVDLLFKREFSYYLIQIYIPCCMLVIVSWVSFWLDQGAVPARVSLGVTTLLTMATQTSGINASLPPVSYTKAIDVWTGVCLTFVFGALLEFALVNYASRSDMHKENMKKKRRDLEQASLDAASDLLDTDSNATFAMKPLVRHPGDPLALEKRLQCEVHMQAPKRPNCCKTWLSKFPTRSKRIDVISRITFPLVFALFNLVYWSTYL 440
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Fly
Match: GluClalpha (gene:FBgn0024963 transcript:FBtr0343788) HSP 1 Score: 236.884 bits (603), Expect = 5.663e-72 Identity = 148/428 (34.58%), Postives = 241/428 (56.31%), Query Frame = 1
Query: 208 IMERIVDKKRYKKDERPSEIYQTN----VLVYMKVLAINSVSVTKMEYSTDVYLRQEWTDPRLTWENLEEFRSFNNNIVSPSLKKILWLPDLFFRNGKEGYVHKMTLPNYLMRLRPNGRILYSQKITMRFSCEMNLQTFPMDSQECLMDIGSYGYTLDELKFTWRKEDPILISTGLQISEFNSPHQVSTIDCTNDSSTSTGKYTCLKAKFLLQRQLGSYLVSTFVPSILIVMVSWLNFWINVDSVPARXXXXXXXXXXXXXQATGISSTLPRVSYIKAIDVWVIACIMFVIGALLEYVVASVLAR--KKKSNGWEKDVREIVRH-ELARWCSA------------CQRQQFFH-LQEQNTLDRNRLEFCSELESLLINHALDAHKGKKTIKT----TPTEDSDIDSYSRFLFPACFLLYNCFYWLYYL 1419
++++I+ +Y RPS I T+ V V + V +I+ + MEYS + R++WTD RL +++++ + ++ + +W+PDLFF N KEG+ H + +PN +R+ PNG +LYS +I++ +C MNL+ +P+D Q C + + SYG+T ++L F W++ DP+ + L + F + + T C +S T+TG+Y+CLK L +R+ YL+ ++P ++V+VSW++FW++ +VPARV+LG+ TLL M TQ +GI+++LP VSY KAIDVW C+ FV GALLE+ + + +R K+N ++++++ R E A +A QF +Q L R+ + + + L + A K KT PT ID SR FP F L+N YW YL
Sbjct: 36 VLDQILGAGKYDARIRPSGINGTDGPAVVRVNIFVRSISKIDDVTMEYSVQLTFREQWTDERLKFDDIQGRLKY----LTLTEANRVWMPDLFFSNEKEGHFHNIIMPNVYIRIFPNGSVLYSIRISLTLACPMNLKLYPLDRQICSLRMASYGWTTNDLVFLWKEGDPVQVVKNLHLPRF-TLEKFLTDYC--NSKTNTGEYSCLKVDLLFKREFSYYLIQIYIPCCMLVIVSWVSFWLDQGAVPARVSLGVTTLLTMATQTSGINASLPPVSYTKAIDVWTGVCLTFVFGALLEFALVNYASRSGSNKANMHKENMKKKRRDLEQASLDAASDLLDTDSNATFAMASQFARGGGQQKPLVRHPGDPLALEKRLQCEVHMQAPKRPNCCKTWLSKFPTRSKRIDVISRITFPLVFALFNLVYWSTYL 456
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Fly
Match: GluClalpha (gene:FBgn0024963 transcript:FBtr0335416) HSP 1 Score: 235.728 bits (600), Expect = 1.020e-71 Identity = 142/412 (34.47%), Postives = 227/412 (55.10%), Query Frame = 1
Query: 208 IMERIVDKKRYKKDERPSEIYQTN----VLVYMKVLAINSVSVTKMEYSTDVYLRQEWTDPRLTWENLEEFRSFNNNIVSPSLKKILWLPDLFFRNGKEGYVHKMTLPNYLMRLRPNGRILYSQKITMRFSCEMNLQTFPMDSQECLMDIGSYGYTLDELKFTWRKEDPILISTGLQISEFNSPHQVSTIDCTNDSSTSTGKYTCLKAKFLLQRQLGSYLVSTFVPSILIVMVSWLNFWINVDSVPARXXXXXXXXXXXXXQATGISSTLPRVSYIKAIDVWVIACIMFVIGALLEYVVASVLARKKKSNGWEKDVREIVRHELARWCSACQRQQFFHLQEQNTLDRNRLEFCSELESLLINHALDAHKGKKTIKT----TPTEDSDIDSYSRFLFPACFLLYNCFYWLYYL 1419
++++I+ +Y RPS I T+ V V + V +I+ + MEYS + R++WTD RL +++++ + ++ + +W+PDLFF N KEG+ H + +PN +R+ PNG +LYS +I++ +C MNL+ +P+D Q C + + SYG+T ++L F W++ DP+ + L + F + + T C +S T+TG+Y+CLK L +R+ YL+ ++P ++V+VSW++FW++ +VPARV+LG+ TLL M TQ +GI+++LP VSY KAIDVW C+ FV GALLE+ + + +R K R + S L R+ + + + L + A K KT PT ID SR FP F L+N YW YL
Sbjct: 36 VLDQILGAGKYDARIRPSGINGTDGPAVVRVNIFVRSISKIDDVTMEYSVQLTFREQWTDERLKFDDIQGRLKY----LTLTEANRVWMPDLFFSNEKEGHFHNIIMPNVYIRIFPNGSVLYSIRISLTLACPMNLKLYPLDRQICSLRMASYGWTTNDLVFLWKEGDPVQVVKNLHLPRF-TLEKFLTDYC--NSKTNTGEYSCLKVDLLFKREFSYYLIQIYIPCCMLVIVSWVSFWLDQGAVPARVSLGVTTLLTMATQTSGINASLPPVSYTKAIDVWTGVCLTFVFGALLEFALVNYASRSDMHKENMKKKRRDLEQASLDAASDLLDTDSNATFAMKPLVRHPGDPLALEKRLQCEVHMQAPKRPNCCKTWLSKFPTRSKRIDVISRITFPLVFALFNLVYWSTYL 440
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Fly
Match: GluClalpha (gene:FBgn0024963 transcript:FBtr0343789) HSP 1 Score: 234.572 bits (597), Expect = 3.980e-71 Identity = 144/421 (34.20%), Postives = 234/421 (55.58%), Query Frame = 1
Query: 208 IMERIVDKKRYKKDERPSEIYQTN----VLVYMKVLAINSVSVTKMEYSTDVYLRQEWTDPRLTWENLEEFRSFNNNIVSPSLKKILWLPDLFFRNGKEGYVHKMTLPNYLMRLRPNGRILYSQKITMRFSCEMNLQTFPMDSQECLMDIGSYGYTLDELKFTWRKEDPILISTGLQISEFNSPHQVSTIDCTNDSSTSTGKYTCLKAKFLLQRQLGSYLVSTFVPSILIVMVSWLNFWINVDSVPARXXXXXXXXXXXXXQATGISSTLPRVSYIKAIDVWVIACIMFVIGALLEYVVASVLARKKKSNGWEKDVREIVRHELARWCSACQRQQFFHLQEQNT-----LDRNRLEFCSELESLLINHALDAHKGKKTIKT----TPTEDSD----IDSYSRFLFPACFLLYNCFYWLYYL 1419
++++I+ +Y RPS I T+ V V + V +I+ + MEYS + R++WTD RL +++++ + ++ + +W+PDLFF N KEG+ H + +PN +R+ PNG +LYS +I++ +C MNL+ +P+D Q C + + SYG+T ++L F W++ DP+ + L + F + + T C +S T+TG+Y+CLK L +R+ YL+ ++P ++V+VSW++FW++ +VPARV+LG+ TLL M TQ +GI+++LP VSY KAIDVW C+ FV GALLE+ + + +R ++ K+ + R +L + S T L R+ + + + L + A K KT PT ID SR FP F L+N YW YL
Sbjct: 36 VLDQILGAGKYDARIRPSGINGTDGPAVVRVNIFVRSISKIDDVTMEYSVQLTFREQWTDERLKFDDIQGRLKY----LTLTEANRVWMPDLFFSNEKEGHFHNIIMPNVYIRIFPNGSVLYSIRISLTLACPMNLKLYPLDRQICSLRMASYGWTTNDLVFLWKEGDPVQVVKNLHLPRF-TLEKFLTDYC--NSKTNTGEYSCLKVDLLFKREFSYYLIQIYIPCCMLVIVSWVSFWLDQGAVPARVSLGVTTLLTMATQTSGINASLPPVSYTKAIDVWTGVCLTFVFGALLEFALVNYASRSDRAADMHKENMKKKRRDLEQ-ASLDAASDLLDTDSNATFAMKPLVRHPGDPLALEKRLQCEVHMQAPKRPNCCKTWLSKFPTRQCSRSKRIDVISRITFPLVFALFNLVYWSTYL 448
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Zebrafish
Match: glra1 (glycine receptor, alpha 1 [Source:NCBI gene;Acc:30676]) HSP 1 Score: 260.766 bits (665), Expect = 5.518e-81 Identity = 148/421 (35.15%), Postives = 237/421 (56.29%), Query Frame = 1
Query: 217 RIVDKKRYKKDERPSEIYQTNVLVYMKVLAINSVSVTKMEYSTDVYLRQEWTDPRLTWENLEEFRSFNNNIVSPSLKKILWLPDLFFRNGKEGYVHKMTLPNYLMRLRPNGRILYSQKITMRFSCEMNLQTFPMDSQECLMDIGSYGYTLDELKFTWRKEDPILISTGLQISEFNSPHQVSTIDCTNDSSTSTGKYTCLKAKFLLQRQLGSYLVSTFVPSILIVMVSWLNFWINVDSVPARXXXXXXXXXXXXXQATGISSTLPRVSYIKAIDVWVIACIMFVIGALLEYVVASVLARKKKSNGWEKDVREIVRHELARWCSACQRQQFFHLQEQNTLDRNRLEFCSELESLLINHALDAHKGKKTIKTTPTEDSD------------------IDSYSRFLFPACFLLYNCFYWLYYLVL 1425
+ +D + K D + NV + + + S++ T M+Y +++LRQ+W DPRL + + ++ + PS+ +W PDLFF N K H++T N L+R+ NG +LYS +IT+ +C M+L+ FPMD Q C+M + S+GYT+++L F W ++ + ++ GL + +F + CT +TGK+TC++A+F L+RQ+G YL+ ++PS+LIV++SW++FWIN+D+ PARV LG+ T+L M TQ++G ++LP+VSY+KAID+W+ C++FV ALLEY + +AR+ K EL R+ QR++ HL+E D R F + A D K PT + ID+ SR FP FL++N FYW+ Y ++
Sbjct: 57 KALDPQGSKSDGTHKKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPD----DSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTK--HYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARQHK--------------ELLRF----QRRRR-HLKEDEAGD-GRFSFAAYGMGPACLQAKDGMAIKGNNNNAPTSTNPPEKTVEEMRKLFISRAKRIDTVSRVAFPLVFLIFNIFYWITYKII 451
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Zebrafish
Match: glra1 (glycine receptor, alpha 1 [Source:NCBI gene;Acc:30676]) HSP 1 Score: 259.61 bits (662), Expect = 1.278e-80 Identity = 148/418 (35.41%), Postives = 235/418 (56.22%), Query Frame = 1
Query: 226 DKKRYKKDERPSEIYQTNVLVYMKVLAINSVSVTKMEYSTDVYLRQEWTDPRLTWENLEEFRSFNNNIVSPSLKKILWLPDLFFRNGKEGYVHKMTLPNYLMRLRPNGRILYSQKITMRFSCEMNLQTFPMDSQECLMDIGSYGYTLDELKFTWRKEDPILISTGLQISEFNSPHQVSTIDCTNDSSTSTGKYTCLKAKFLLQRQLGSYLVSTFVPSILIVMVSWLNFWINVDSVPARXXXXXXXXXXXXXQATGISSTLPRVSYIKAIDVWVIACIMFVIGALLEYVVASVLARKKKSNGWEKDVREIVRHELARWCSACQRQQFFHLQEQNTLDRNRLEFCSELESLLINHALDAHKGKKTIKTTPTEDSD------------------IDSYSRFLFPACFLLYNCFYWLYYLVL 1425
D + K D + NV + + + S++ T M+Y +++LRQ+W DPRL + + ++ + PS+ +W PDLFF N K H++T N L+R+ NG +LYS +IT+ +C M+L+ FPMD Q C+M + S+GYT+++L F W ++ + ++ GL + +F + CT +TGK+TC++A+F L+RQ+G YL+ ++PS+LIV++SW++FWIN+D+ PARV LG+ T+L M TQ++G ++LP+VSY+KAID+W+ C++FV ALLEY + +AR+ K EL R+ QR++ HL+E D R F + A D K PT + ID+ SR FP FL++N FYW+ Y ++
Sbjct: 58 DPQGSKSDGTHKKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPD----DSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTK--HYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARQHK--------------ELLRF----QRRRR-HLKEDEAGD-GRFSFAAYGMGPACLQAKDGMAIKGNNNNAPTSTNPPEKTVEEMRKLFISRAKRIDTVSRVAFPLVFLIFNIFYWITYKII 449
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Zebrafish
Match: glra1 (glycine receptor, alpha 1 [Source:NCBI gene;Acc:30676]) HSP 1 Score: 258.84 bits (660), Expect = 2.378e-80 Identity = 145/402 (36.07%), Postives = 230/402 (57.21%), Query Frame = 1
Query: 274 TNVLVYMKVLAINSVSVTKMEYSTDVYLRQEWTDPRLTWENLEEFRSFNNNIVSPSLKKILWLPDLFFRNGKEGYVHKMTLPNYLMRLRPNGRILYSQKITMRFSCEMNLQTFPMDSQECLMDIGSYGYTLDELKFTWRKEDPILISTGLQISEFNSPHQVSTIDCTNDSSTSTGKYTCLKAKFLLQRQLGSYLVSTFVPSILIVMVSWLNFWINVDSVPARXXXXXXXXXXXXXQATGISSTLPRVSYIKAIDVWVIACIMFVIGALLEYVVASVLARKKKSNGWEKDVREIVRHELARWCSACQRQQFFHLQEQNTLDRNRLEFCSELESLLINHALDAHKGKKTIKTTPTEDSD------------------IDSYSRFLFPACFLLYNCFYWLYYLVL 1425
NV + + + S++ T M+Y +++LRQ+W DPRL + + ++ + PS+ +W PDLFF N K H++T N L+R+ NG +LYS +IT+ +C M+L+ FPMD Q C+M + S+GYT+++L F W ++ + ++ GL + +F + CT +TGK+TC++A+F L+RQ+G YL+ ++PS+LIV++SW++FWIN+D+ PARV LG+ T+L M TQ++G ++LP+VSY+KAID+W+ C++FV ALLEY + +AR+ K EL R+ QR++ HL+E D R F + A D K PT + ID+ SR FP FL++N FYW+ Y ++
Sbjct: 61 VNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPD----DSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCT--KHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARQHK--------------ELLRF----QRRRR-HLKEDEAGD-GRFSFAAYGMGPACLQAKDGMAIKGNNNNAPTSTNPPEKTVEEMRKLFISRAKRIDTVSRVAFPLVFLIFNIFYWITYKII 436
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Zebrafish
Match: glra3 (glycine receptor, alpha 3 [Source:ZFIN;Acc:ZDB-GENE-020402-1]) HSP 1 Score: 258.455 bits (659), Expect = 3.822e-80 Identity = 152/451 (33.70%), Postives = 245/451 (54.32%), Query Frame = 1
Query: 175 RKSPMAQQRDLIMERIVDKKRYKKDERPS-EIYQTNVLVYMKVLAINSVSVTKMEYSTDVYLRQEWTDPRLTWENLEEFRSFNNNIVSPSLKKILWLPDLFFRNGKEGYVHKMTLPNYLMRLRPNGRILYSQKITMRFSCEMNLQTFPMDSQECLMDIGSYGYTLDELKFTWRKEDPILISTGLQISEFNSPHQVSTIDCTNDSSTSTGKYTCLKAKFLLQRQLGSYLVSTFVPSILIVMVSWLNFWINVDSVPARXXXXXXXXXXXXXQATGISSTLPRVSYIKAIDVWVIACIMFVIGALLEYVVASVLARKKKS----------NGWEKDVREIVRHELARWCSACQRQQFFHLQEQNTLDRNRLEFCSELESLLINHALDAH--KGKKTIKTTPTEDS-------------------DIDSYSRFLFPACFLLYNCFYWLYYLVLVH 1431
R +PM+ D + + + Y RP+ + NV + + + S++ T M+Y +++LRQ+W DPRL + + ++ + PS+ +W PDLFF N K + H++T N L+R+ NG +LYS ++T+ SC M+L+ FPMD Q C+M + S+GYT+++L F W+++ P+ ++ GL + +F + CT +TGK+TC++ +F L+RQ+G YL+ ++PS+LIV++SW++FWIN+D+ PARV LG+ T+L M TQ++G ++LP+VSY+KAID+W+ C++FV ALLEY + ++R+ K +G E++VRE +RL F N D K TTP+E + ID+ SR FP FL +N FYW+ Y +L H
Sbjct: 37 RAAPMSPS-DFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPD----DSLDLDPSMLDSIWKPDLFFANEKGAHFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQEKGPVQVADGLTLPQFILKDESDLRYCTK--HYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRTSLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRRRKKSGKEEEVRE-----------------------------SRLSFTP-------NAGKDGAVPKTANNAATTPSEPAVAPGKSHEEMRKLFIDRAKKIDTVSRAGFPLAFLFFNIFYWVLYKILRH 444
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Zebrafish
Match: glra2 (glycine receptor, alpha 2 [Source:ZFIN;Acc:ZDB-GENE-090407-1]) HSP 1 Score: 258.07 bits (658), Expect = 4.271e-80 Identity = 144/399 (36.09%), Postives = 235/399 (58.90%), Query Frame = 1
Query: 277 NVLVYMKVLAINSVSVTKMEYSTDVYLRQEWTDPRLTWENLEEFRSFNNNIVSPSLKKILWLPDLFFRNGKEGYVHKMTLPNYLMRLRPNGRILYSQKITMRFSCEMNLQTFPMDSQECLMDIGSYGYTLDELKFTWRKEDPILISTGLQISEFNSPHQVSTIDCTNDSSTSTGKYTCLKAKFLLQRQLGSYLVSTFVPSILIVMVSWLNFWINVDSVPARXXXXXXXXXXXXXQATGISSTLPRVSYIKAIDVWVIACIMFVIGALLEYVVASVLARKKKSNGWEKDVREIVRHELARWCSACQRQQFFHLQEQNTLDRNRLEF-------CSELESLLINHALDAHKGKKTIKTTPTEDSD-------IDSYSRFLFPACFLLYNCFYWLYYLVLVH 1431
NV + + + SV+ T M+Y +++LRQ+W DPRL + + ++ + PS+ +W PDLFF N K H +T N L+R+ +G +LYS ++T+ SC M+L+ FPMD Q C M + S+GYT+++L F W + P+ ++ GL + +F + CT +TGK+TC++ KF L+RQ+G YL+ ++PS+LIV++SW++FWIN+D+ PARV LG+ T+L M TQ++G ++LP+VSY+KAID+W+ C++FV ALLEY + ++R++K E +R + +RQ+ Q++ L RL F C + +++ N ++ + +K T T ID+ SR FP FL++N FYW+ Y ++ H
Sbjct: 70 NVTCNIFINSFGSVTETTMDYRVNIFLRQKWNDPRLAYSEYPD----SSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRIFKDGTVLYSIRLTLILSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWLDKGPVQVADGLTLPQFLIRDEKDLGYCTK--HYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAGVNFVSRQQK---------EFLRLK--------RRQR--RTQKEEDLQDGRLHFSSYNTTTCVKDGAVVKNTQVNQIQQPSILKNTETNRKKFVDRAKRIDTISRAAFPLAFLIFNVFYWITYKIIRH 443
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Xenopus
Match: GLRA3 (glycine receptor alpha 3 [Source:NCBI gene;Acc:100488938]) HSP 1 Score: 256.529 bits (654), Expect = 1.598e-79 Identity = 149/433 (34.41%), Postives = 244/433 (56.35%), Query Frame = 1
Query: 175 RKSPMAQQRDLIMERIVDKKRYKKDERPS-EIYQTNVLVYMKVLAINSVSVTKMEYSTDVYLRQEWTDPRLTWENLEEFRSFNNNIVSPSLKKILWLPDLFFRNGKEGYVHKMTLPNYLMRLRPNGRILYSQKITMRFSCEMNLQTFPMDSQECLMDIGSYGYTLDELKFTWRKEDPILISTGLQISEFNSPHQVSTIDCTNDSSTSTGKYTCLKAKFLLQRQLGSYLVSTFVPSILIVMVSWLNFWINVDSVPARXXXXXXXXXXXXXQATGISSTLPRVSYIKAIDVWVIACIMFVIGALLEYVVASVLARKKKSNGWEKDVREIVRHELARWCSACQRQQFFHLQEQNTLDRNRLEFCSELESLLINHALDAHKGKKTIKTTPTEDSD-------------IDSYSRFLFPACFLLYNCFYWLYYLVLVH 1431
R SPM+ D + + + Y RP+ + NV + V + S++ T M+Y +++LRQ+W DPRL + + ++ + PS+ +W PDLFF N K H++T N L+R+ +G +LYS ++T+ SC M+L+ FPMD Q C+M + S+GYT+++L F W++ P+ I+ GL + +F + CT +TGK+TC++ +F L+RQ+G YL+ ++PS+LIV++SW++FWIN+D+ PARV LG+ T+L M TQ++G ++LP+VSY+KAID+W+ C++FV ALLEY + ++R+ K EL R+ ++ + ++E +R F + + A D K + P + ID+ SR FP FL++N FYW+ Y +L H
Sbjct: 20 RPSPMSPS-DFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFVNSFGSIAETTMDYRLNIFLRQKWNDPRLAYSEYPD----DSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKDGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQENGPVQIADGLTLPQFVLKEEKDLRYCTK--HYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHK--------------ELLRFRRKRKKDRDDDVRE------SRFSFTAYGMGPCL-QAKDGVNPKGPLNAPPAPKTHEEMRKVFIDRAKKIDTLSRACFPLAFLIFNIFYWVIYKILRH 424
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Xenopus
Match: GLRA3 (glycine receptor alpha 3 [Source:NCBI gene;Acc:100488938]) HSP 1 Score: 256.144 bits (653), Expect = 2.791e-79 Identity = 149/433 (34.41%), Postives = 244/433 (56.35%), Query Frame = 1
Query: 175 RKSPMAQQRDLIMERIVDKKRYKKDERPS-EIYQTNVLVYMKVLAINSVSVTKMEYSTDVYLRQEWTDPRLTWENLEEFRSFNNNIVSPSLKKILWLPDLFFRNGKEGYVHKMTLPNYLMRLRPNGRILYSQKITMRFSCEMNLQTFPMDSQECLMDIGSYGYTLDELKFTWRKEDPILISTGLQISEFNSPHQVSTIDCTNDSSTSTGKYTCLKAKFLLQRQLGSYLVSTFVPSILIVMVSWLNFWINVDSVPARXXXXXXXXXXXXXQATGISSTLPRVSYIKAIDVWVIACIMFVIGALLEYVVASVLARKKKSNGWEKDVREIVRHELARWCSACQRQQFFHLQEQNTLDRNRLEFCSELESLLINHALDAHKGKKTIKTTPTEDSD-------------IDSYSRFLFPACFLLYNCFYWLYYLVLVH 1431
R SPM+ D + + + Y RP+ + NV + V + S++ T M+Y +++LRQ+W DPRL + + ++ + PS+ +W PDLFF N K H++T N L+R+ +G +LYS ++T+ SC M+L+ FPMD Q C+M + S+GYT+++L F W++ P+ I+ GL + +F + CT +TGK+TC++ +F L+RQ+G YL+ ++PS+LIV++SW++FWIN+D+ PARV LG+ T+L M TQ++G ++LP+VSY+KAID+W+ C++FV ALLEY + ++R+ K EL R+ ++ + ++E +R F + + A D K + P + ID+ SR FP FL++N FYW+ Y +L H
Sbjct: 32 RPSPMSPS-DFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFVNSFGSIAETTMDYRLNIFLRQKWNDPRLAYSEYPD----DSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKDGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQENGPVQIADGLTLPQFVLKEEKDLRYCTK--HYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHK--------------ELLRFRRKRKKDRDDDVRE------SRFSFTAYGMGPCL-QAKDGVNPKGPLNAPPAPKTHEEMRKVFIDRAKKIDTLSRACFPLAFLIFNIFYWVIYKILRH 436
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Xenopus
Match: tal1 (T-cell acute lymphocytic leukemia 1 [Source:Xenbase;Acc:XB-GENE-479827]) HSP 1 Score: 255.373 bits (651), Expect = 4.192e-79 Identity = 143/420 (34.05%), Postives = 238/420 (56.67%), Query Frame = 1
Query: 178 KSPMAQQRDLIMERIVDKKRYKKDERPS-EIYQTNVLVYMKVLAINSVSVTKMEYSTDVYLRQEWTDPRLTWENLEEFRSFNNNIVSPSLKKILWLPDLFFRNGKEGYVHKMTLPNYLMRLRPNGRILYSQKITMRFSCEMNLQTFPMDSQECLMDIGSYGYTLDELKFTWRKEDPILISTGLQISEFNSPHQVSTIDCTNDSSTSTGKYTCLKAKFLLQRQLGSYLVSTFVPSILIVMVSWLNFWINVDSVPARXXXXXXXXXXXXXQATGISSTLPRVSYIKAIDVWVIACIMFVIGALLEYVVASVLARKKKSNGWEKDVREIVRHELARWCSACQRQQFFHLQEQNTLDRNRLEFCSELESLLINHALDAHKGKKTIKTTPTEDSD-IDSYSRFLFPACFLLYNCFYWLYYLVLVH 1431
KSP D + + + Y RP+ + NV + + + S++ T M+Y +++LRQ W DPRL++ + ++ + PS+ +W PDLFF N K H +T N L+R+ NG +LYS ++T+ SC M+L+ FPMD Q C M + S+GYT+++L F W P+ ++ GL + +F + CT +TGK+TC++ KF L+RQ+G YL+ ++PS+LIV++SW++FWIN+D+ PARV LG+ T+L M TQ++G ++LP+VSY+KAID+W+ C++FV ALLEY + ++R+ K + ++ E R+ F+ +++ + +++ K +IK + + ID+ SR FP FL++N FYW+ Y ++ H
Sbjct: 14 KSPPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQTWNDPRLSYSEYPD----DSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCAMQLESFGYTMNDLIFEWLSTSPVQVADGLTLPQFILKEENELGYCTK--HYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQHKEFLRLRRRQKRQSKE-----EDVARESRFNFSGYGMGHCLQVKDGTAVKATPPIPPPPQPKDADSIKKKFVDRAKRIDTISRAAFPLAFLIFNIFYWITYKIIRH 422
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Xenopus
Match: tal1 (T-cell acute lymphocytic leukemia 1 [Source:Xenbase;Acc:XB-GENE-479827]) HSP 1 Score: 256.144 bits (653), Expect = 4.388e-79 Identity = 144/420 (34.29%), Postives = 238/420 (56.67%), Query Frame = 1
Query: 178 KSPMAQQRDLIMERIVDKKRYKKDERPS-EIYQTNVLVYMKVLAINSVSVTKMEYSTDVYLRQEWTDPRLTWENLEEFRSFNNNIVSPSLKKILWLPDLFFRNGKEGYVHKMTLPNYLMRLRPNGRILYSQKITMRFSCEMNLQTFPMDSQECLMDIGSYGYTLDELKFTWRKEDPILISTGLQISEFNSPHQVSTIDCTNDSSTSTGKYTCLKAKFLLQRQLGSYLVSTFVPSILIVMVSWLNFWINVDSVPARXXXXXXXXXXXXXQATGISSTLPRVSYIKAIDVWVIACIMFVIGALLEYVVASVLARKKKSNGWEKDVREIVRHELARWCSACQRQQFFHLQEQNTLDRNRLEFCSELESLLINHALDAHKGKKTIKTTPTEDSD-IDSYSRFLFPACFLLYNCFYWLYYLVLVH 1431
KSP D + + + Y RP+ + NV + + + SV+ T M+Y +++LRQ W DPRL++ + ++ + PS+ +W PDLFF N K H +T N L+R+ NG +LYS ++T+ SC M+L+ FPMD Q C M + S+GYT+++L F W P+ ++ GL + +F + CT +TGK+TC++ KF L+RQ+G YL+ ++PS+LIV++SW++FWIN+D+ PARV LG+ T+L M TQ++G ++LP+VSY+KAID+W+ C++FV ALLEY + ++R+ K + ++ E R+ F+ +++ + +++ K +IK + + ID+ SR FP FL++N FYW+ Y ++ H
Sbjct: 36 KSPPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQTWNDPRLSYSEYPD----DSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCAMQLESFGYTMNDLIFEWLSTSPVQVADGLTLPQFILKEENELGYCTK--HYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQHKEFLRLRRRQKRQSKE-----EDVARESRFNFSGYGMGHCLQVKDGTAVKATPPIPPPPQPKDADSIKKKFVDRAKRIDTISRAAFPLAFLIFNIFYWITYKIIRH 444
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Xenopus
Match: tal1 (T-cell acute lymphocytic leukemia 1 [Source:Xenbase;Acc:XB-GENE-479827]) HSP 1 Score: 254.988 bits (650), Expect = 5.092e-79 Identity = 143/420 (34.05%), Postives = 238/420 (56.67%), Query Frame = 1
Query: 178 KSPMAQQRDLIMERIVDKKRYKKDERPS-EIYQTNVLVYMKVLAINSVSVTKMEYSTDVYLRQEWTDPRLTWENLEEFRSFNNNIVSPSLKKILWLPDLFFRNGKEGYVHKMTLPNYLMRLRPNGRILYSQKITMRFSCEMNLQTFPMDSQECLMDIGSYGYTLDELKFTWRKEDPILISTGLQISEFNSPHQVSTIDCTNDSSTSTGKYTCLKAKFLLQRQLGSYLVSTFVPSILIVMVSWLNFWINVDSVPARXXXXXXXXXXXXXQATGISSTLPRVSYIKAIDVWVIACIMFVIGALLEYVVASVLARKKKSNGWEKDVREIVRHELARWCSACQRQQFFHLQEQNTLDRNRLEFCSELESLLINHALDAHKGKKTIKTTPTEDSD-IDSYSRFLFPACFLLYNCFYWLYYLVLVH 1431
KSP D + + + Y RP+ + NV + + + S++ T M+Y +++LRQ W DPRL++ + ++ + PS+ +W PDLFF N K H +T N L+R+ NG +LYS ++T+ SC M+L+ FPMD Q C M + S+GYT+++L F W P+ ++ GL + +F + CT +TGK+TC++ KF L+RQ+G YL+ ++PS+LIV++SW++FWIN+D+ PARV LG+ T+L M TQ++G ++LP+VSY+KAID+W+ C++FV ALLEY + ++R+ K + ++ E R+ F+ +++ + +++ K +IK + + ID+ SR FP FL++N FYW+ Y ++ H
Sbjct: 16 KSPPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQTWNDPRLSYSEYPD----DSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCAMQLESFGYTMNDLIFEWLSTSPVQVADGLTLPQFILKEENELGYCTK--HYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQHKEFLRLRRRQKRQSKE-----EDVARESRFNFSGYGMGHCLQVKDGTAVKATPPIPPPPQPKDADSIKKKFVDRAKRIDTISRAAFPLAFLIFNIFYWITYKIIRH 424
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Mouse
Match: Glra3 (glycine receptor, alpha 3 subunit [Source:MGI Symbol;Acc:MGI:95749]) HSP 1 Score: 261.151 bits (666), Expect = 7.729e-81 Identity = 150/436 (34.40%), Postives = 250/436 (57.34%), Query Frame = 1
Query: 175 RKSPMAQQRDLIMERIVDKKRYKKDERPS-EIYQTNVLVYMKVLAINSVSVTKMEYSTDVYLRQEWTDPRLTWENLEEFRSFNNNIVSPSLKKILWLPDLFFRNGKEGYVHKMTLPNYLMRLRPNGRILYSQKITMRFSCEMNLQTFPMDSQECLMDIGSYGYTLDELKFTWRKEDPILISTGLQISEFNSPHQVSTIDCTNDSSTSTGKYTCLKAKFLLQRQLGSYLVSTFVPSILIVMVSWLNFWINVDSVPARXXXXXXXXXXXXXQATGISSTLPRVSYIKAIDVWVIACIMFVIGALLEYVVASVLARKKKSNGWEKDVREIVRHELARW--CSACQRQQFFHLQE-QNTLDRNRLEF-------CSELESLLI----NHALDA--HKGKKTIKTTPTEDSDIDSYSRFLFPACFLLYNCFYWLYYLVLVH 1431
R +PM+ D + + + Y RP+ + NV + + + S++ T M+Y +++LRQ+W DPRL + + ++ + PS+ +W PDLFF N K H++T N L+R+ NG +LYS ++T+ SC M+L+ FPMD Q C+M + S+GYT+++L F W+ E P+ ++ GL + +F + CT +TGK+TC++ +F L+RQ+G YL+ ++PS+LIV++SW++FWIN+D+ PARV LG+ T+L M TQ++G ++LP+VSY+KAID+W+ C++FV ALLEY + ++R+ K E++R R A ++F+ + + + +R F C + + ++ NHA+ + K ID+ SR FP FL++N FYW+ Y +L H
Sbjct: 53 RSAPMSPS-DFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPD----DSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQDEAPVQVAEGLTLPQFLLKEEKDLRYCTK--HYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHK---------ELLRFRRKRKNKTEAFALEKFYRFSDTDDEVRESRFSFTAYGMGPCLQAKDGVVPKGPNHAVQVMPKSPDEMRKVFIDRAKKIDTISRACFPLAFLIFNIFYWVIYKILRH 472
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Mouse
Match: Glra2 (glycine receptor, alpha 2 subunit [Source:MGI Symbol;Acc:MGI:95748]) HSP 1 Score: 254.603 bits (649), Expect = 1.061e-78 Identity = 137/386 (35.49%), Postives = 227/386 (58.81%), Query Frame = 1
Query: 277 NVLVYMKVLAINSVSVTKMEYSTDVYLRQEWTDPRLTWENLEEFRSFNNNIVSPSLKKILWLPDLFFRNGKEGYVHKMTLPNYLMRLRPNGRILYSQKITMRFSCEMNLQTFPMDSQECLMDIGSYGYTLDELKFTWRKEDPILISTGLQISEFNSPHQVSTIDCTNDSSTSTGKYTCLKAKFLLQRQLGSYLVSTFVPSILIVMVSWLNFWINVDSVPARXXXXXXXXXXXXXQATGISSTLPRVSYIKAIDVWVIACIMFVIGALLEYVVASVLARKKKSNGWEKDVREIVRHELARWCSACQRQQFFHLQEQNTLDRNRLEFCSELESLLINHALDAHKGKKTIKTTPTEDSD-IDSYSRFLFPACFLLYNCFYWLYYLVLVH 1431
NV + + + SV+ T M+Y +++LRQ+W D RL + + ++ + PS+ +W PDLFF N K H +T N L+R+ NG++LYS ++T+ SC M+L+ FPMD Q C M + S+GYT+++L F W + P+ ++ GL + +F + CT +TGK+TC++ KF L+RQ+G YL+ ++PS+LIV++SW++FWIN+D+ PARV LG+ T+L M TQ++G ++LP+VSY+KAID+W+ C++FV ALLEY + ++R+ K + ++ E R+ F+ +++ + +++ N K IK + + ID+ SR FP FL++N FYW+ Y ++ H
Sbjct: 72 NVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPD----DSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWLSDGPVQVAEGLTLPQFILKEEKELGYCTK--HYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQHKEFLRLRRRQKRQNKE-----EDVTRESRFNFSGYGMGHCLQMKDGTAVKATPANPLPQPPKDADAIKKKFVDRAKRIDTISRAAFPLAFLIFNIFYWITYKIIRH 446
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Mouse
Match: Glra1 (glycine receptor, alpha 1 subunit [Source:MGI Symbol;Acc:MGI:95747]) HSP 1 Score: 247.669 bits (631), Expect = 5.293e-76 Identity = 137/403 (34.00%), Postives = 226/403 (56.08%), Query Frame = 1
Query: 274 TNVLVYMKVLAINSVSVTKMEYSTDVYLRQEWTDPRLTWENLEEFRSFNNNIVSPSLKKILWLPDLFFRNGKEGYVHKMTLPNYLMRLRPNGRILYSQKITMRFSCEMNLQTFPMDSQECLMDIGSYGYTLDELKFTWRKEDPILISTGLQISEFNSPHQVSTIDCTNDSSTSTGKYTCLKAKFLLQRQLGSYLVSTFVPSILIVMVSWLNFWINVDSVPARXXXXXXXXXXXXXQATGISSTLPRVSYIKAIDVWVIACIMFVIGALLEYVVASVLARKKKSNGWEKDVREIVRHELARWCSACQRQQFFHLQEQNTLDRNRLEFCSELESLLINHALDAHKGKK-----------TIKTTPTE--------DSDIDSYSRFLFPACFLLYNCFYWLYYLVL 1425
NV + + + S++ T M+Y +++LRQ+W DPRL + + ++ + PS+ +W PDLFF N K + H++T N L+R+ NG +LYS +IT+ +C M+L+ FPMD Q C+M + S+GYT+++L F W+++ + ++ GL + +F + CT +TGK+TC++A+F L+RQ+G YL+ ++PS+LIV++SW++FWIN+D+ PARV LG+ T+L M TQ++G ++LP+VSY+KAID+W+ C++FV ALLEY + ++R+ K + R + + +L + + R F + A D K +P E ID SR FP FL++N FYW+ Y ++
Sbjct: 65 VNVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYNEYPD----DSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQEQGAVQVADGLTLPQFILKEEKDLRYCTK--HYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWISFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRKRRHHKSPM------------LNLFQDDEGGEGRFNFSAYGMGPACLQAKDGISVKGANNNNTTNPPPAPSKSPEEMRKLFIQRAKKIDKISRIGFPMAFLIFNMFYWIIYKIV 449
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Mouse
Match: Glra4 (glycine receptor, alpha 4 subunit [Source:MGI Symbol;Acc:MGI:95750]) HSP 1 Score: 245.743 bits (626), Expect = 2.905e-75 Identity = 139/391 (35.55%), Postives = 226/391 (57.80%), Query Frame = 1
Query: 274 TNVLVYMKVLAINSVSVTKMEYSTDVYLRQEWTDPRLTWENLEEFRSFNNNIVSPSLKKILWLPDLFFRNGKEGYVHKMTLPNYLMRLRPNGRILYSQKITMRFSCEMNLQTFPMDSQECLMDIGSYGYTLDELKFTWRKEDP-ILISTGLQISEFNSPHQVSTIDCTNDSSTSTGKYTCLKAKFLLQRQLGSYLVSTFVPSILIVMVSWLNFWINVDSVPARXXXXXXXXXXXXXQATGISSTLPRVSYIKAIDVWVIACIMFVIGALLEYVVASVLARKKKS------NGWEKDVREIVRHELARWCSACQRQQFFHLQEQNTLDRNRLEFCSELESLLINHALDAHKGKKTIKTTPTEDSDIDSYSRFLFPACFLLYNCFYWLYYLVL 1425
NV + + + SV+ T M+Y +V+LRQ+W DPRL + + ++ + PS+ +W PDLFF N K H++T N L+R+ NG +LYS ++T+ SC M+L+ FPMD Q C M + S+GYT+++L F W ++ P + ++ GL + +F + CT +TGK+TC++ KF L+RQ+G YL+ ++PS+LIV++SW++FWIN+D+ PARV LG+ T+L M TQ++G ++LP+VSY+KAID+W+ C++FV ALLEY + ++R+ K + + E + E + ++ ++ + + LL +G+ K ID+ SR +FP FL++N FYW+ Y VL
Sbjct: 70 VNVTCNIFINSFGSVTETTMDYRVNVFLRQQWNDPRLAYREYPD----DSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLILSCPMDLKNFPMDIQTCTMQLESFGYTMNDLMFEWLEDAPAVQVAEGLTLPQFILRDEKDLGYCTK--HYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQHKEFMRLRRRQRRQRMEEDIIRESRFYFRGYGLGHCLQARDGGPMEGSSIYSPQPPTPLL-------KEGETMRKLYVDRAKRIDTISRAVFPFTFLVFNIFYWVVYKVL 447
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Mouse
Match: Glra1 (glycine receptor, alpha 1 subunit [Source:MGI Symbol;Acc:MGI:95747]) HSP 1 Score: 243.047 bits (619), Expect = 3.173e-74 Identity = 115/282 (40.78%), Postives = 191/282 (67.73%), Query Frame = 1
Query: 274 TNVLVYMKVLAINSVSVTKMEYSTDVYLRQEWTDPRLTWENLEEFRSFNNNIVSPSLKKILWLPDLFFRNGKEGYVHKMTLPNYLMRLRPNGRILYSQKITMRFSCEMNLQTFPMDSQECLMDIGSYGYTLDELKFTWRKEDPILISTGLQISEFNSPHQVSTIDCTNDSSTSTGKYTCLKAKFLLQRQLGSYLVSTFVPSILIVMVSWLNFWINVDSVPARXXXXXXXXXXXXXQATGISSTLPRVSYIKAIDVWVIACIMFVIGALLEYVVASVLARKKK 1119
NV + + + S++ T M+Y +++LRQ+W DPRL + + ++ + PS+ +W PDLFF N K + H++T N L+R+ NG +LYS +IT+ +C M+L+ FPMD Q C+M + S+GYT+++L F W+++ + ++ GL + +F + CT +TGK+TC++A+F L+RQ+G YL+ ++PS+LIV++SW++FWIN+D+ PARV LG+ T+L M TQ++G ++LP+VSY+KAID+W+ C++FV ALLEY + ++R+ K
Sbjct: 65 VNVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYNEYPD----DSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQEQGAVQVADGLTLPQFILKEEKDLRYCTK--HYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWISFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHK 340
BLAST of Glycine receptor subunit alpha-3 vs. UniProt/SwissProt
Match: sp|P24524|GLRA3_RAT (Glycine receptor subunit alpha-3 OS=Rattus norvegicus OX=10116 GN=Glra3 PE=1 SV=1) HSP 1 Score: 263.462 bits (672), Expect = 4.081e-81 Identity = 151/436 (34.63%), Postives = 251/436 (57.57%), Query Frame = 1
Query: 175 RKSPMAQQRDLIMERIVDKKRYKKDERPS-EIYQTNVLVYMKVLAINSVSVTKMEYSTDVYLRQEWTDPRLTWENLEEFRSFNNNIVSPSLKKILWLPDLFFRNGKEGYVHKMTLPNYLMRLRPNGRILYSQKITMRFSCEMNLQTFPMDSQECLMDIGSYGYTLDELKFTWRKEDPILISTGLQISEFNSPHQVSTIDCTNDSSTSTGKYTCLKAKFLLQRQLGSYLVSTFVPSILIVMVSWLNFWINVDSVPARXXXXXXXXXXXXXQATGISSTLPRVSYIKAIDVWVIACIMFVIGALLEYVVASVLARKKKSNGWEKDVREIVRHELAR--WCSACQRQQFFHLQE-QNTLDRNRLEF-------CSELESLLI----NHALDA--HKGKKTIKTTPTEDSDIDSYSRFLFPACFLLYNCFYWLYYLVLVH 1431
R +PM+ D + + + Y RP+ + NV + + + S++ T M+Y +++LRQ+W DPRL + + ++ + PS+ +W PDLFF N K H++T N L+R+ NG +LYS ++T+ SC M+L+ FPMD Q C+M + S+GYT+++L F W+ E P+ ++ GL + +F + CT +TGK+TC++ +F L+RQ+G YL+ ++PS+LIV++SW++FWIN+D+ PARV LG+ T+L M TQ++G ++LP+VSY+KAID+W+ C++FV ALLEY + ++R+ K E++R R A ++F+ + + + +RL F C + + ++ NHA+ + K ID+ SR FP FL++N FYW+ Y +L H
Sbjct: 37 RSAPMSPS-DFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPD----DSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQDEAPVQVAEGLTLPQFLLKEEKDLRYCTK--HYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHK---------ELLRFRRKRKNKTEAFALEKFYRFSDTDDEVRESRLSFTAYGMGPCLQAKDGVVPKGPNHAVQVMPKSADEMRKVFIDRAKKIDTISRACFPLAFLIFNIFYWVIYKILRH 456
BLAST of Glycine receptor subunit alpha-3 vs. UniProt/SwissProt
Match: sp|Q91XP5|GLRA3_MOUSE (Glycine receptor subunit alpha-3 OS=Mus musculus OX=10090 GN=Glra3 PE=1 SV=2) HSP 1 Score: 261.151 bits (666), Expect = 3.326e-80 Identity = 150/436 (34.40%), Postives = 250/436 (57.34%), Query Frame = 1
Query: 175 RKSPMAQQRDLIMERIVDKKRYKKDERPS-EIYQTNVLVYMKVLAINSVSVTKMEYSTDVYLRQEWTDPRLTWENLEEFRSFNNNIVSPSLKKILWLPDLFFRNGKEGYVHKMTLPNYLMRLRPNGRILYSQKITMRFSCEMNLQTFPMDSQECLMDIGSYGYTLDELKFTWRKEDPILISTGLQISEFNSPHQVSTIDCTNDSSTSTGKYTCLKAKFLLQRQLGSYLVSTFVPSILIVMVSWLNFWINVDSVPARXXXXXXXXXXXXXQATGISSTLPRVSYIKAIDVWVIACIMFVIGALLEYVVASVLARKKKSNGWEKDVREIVRHELARW--CSACQRQQFFHLQE-QNTLDRNRLEF-------CSELESLLI----NHALDA--HKGKKTIKTTPTEDSDIDSYSRFLFPACFLLYNCFYWLYYLVLVH 1431
R +PM+ D + + + Y RP+ + NV + + + S++ T M+Y +++LRQ+W DPRL + + ++ + PS+ +W PDLFF N K H++T N L+R+ NG +LYS ++T+ SC M+L+ FPMD Q C+M + S+GYT+++L F W+ E P+ ++ GL + +F + CT +TGK+TC++ +F L+RQ+G YL+ ++PS+LIV++SW++FWIN+D+ PARV LG+ T+L M TQ++G ++LP+VSY+KAID+W+ C++FV ALLEY + ++R+ K E++R R A ++F+ + + + +R F C + + ++ NHA+ + K ID+ SR FP FL++N FYW+ Y +L H
Sbjct: 37 RSAPMSPS-DFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPD----DSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQDEAPVQVAEGLTLPQFLLKEEKDLRYCTK--HYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHK---------ELLRFRRKRKNKTEAFALEKFYRFSDTDDEVRESRFSFTAYGMGPCLQAKDGVVPKGPNHAVQVMPKSPDEMRKVFIDRAKKIDTISRACFPLAFLIFNIFYWVIYKILRH 456
BLAST of Glycine receptor subunit alpha-3 vs. UniProt/SwissProt
Match: sp|O75311|GLRA3_HUMAN (Glycine receptor subunit alpha-3 OS=Homo sapiens OX=9606 GN=GLRA3 PE=1 SV=2) HSP 1 Score: 259.996 bits (663), Expect = 9.438e-80 Identity = 151/440 (34.32%), Postives = 249/440 (56.59%), Query Frame = 1
Query: 175 RKSPMAQQRDLIMERIVDKKRYKKDERPS-EIYQTNVLVYMKVLAINSVSVTKMEYSTDVYLRQEWTDPRLTWENLEEFRSFNNNIVSPSLKKILWLPDLFFRNGKEGYVHKMTLPNYLMRLRPNGRILYSQKITMRFSCEMNLQTFPMDSQECLMDIGSYGYTLDELKFTWRKEDPILISTGLQISEFNSPHQVSTIDCTNDSSTSTGKYTCLKAKFLLQRQLGSYLVSTFVPSILIVMVSWLNFWINVDSVPARXXXXXXXXXXXXXQATGISSTLPRVSYIKAIDVWVIACIMFVIGALLEYVVASVLARKKKSNGWEKDVREIVRHELAR--WCSACQRQQFFHLQEQNTLDR-NRLEFCSELESLLINHALDAHKGK---------KTIKTTPTE--------DSDIDSYSRFLFPACFLLYNCFYWLYYLVLVH 1431
R +PM+ D + + + Y RP+ + NV + + + S++ T M+Y +++LRQ+W DPRL + + ++ + PS+ +W PDLFF N K H++T N L+R+ NG +LYS ++T+ SC M+L+ FPMD Q C+M + S+GYT+++L F W+ E P+ ++ GL + +F + CT +TGK+TC++ +F L+RQ+G YL+ ++PS+LIV++SW++FWIN+D+ PARV LG+ T+L M TQ++G ++LP+VSY+KAID+W+ C++FV ALLEY + ++R+ K E++R R A ++F+ + + R +R F + + L A G + + +P E ID+ SR FP FL++N FYW+ Y +L H
Sbjct: 37 RSAPMSPS-DFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPD----DSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQDEAPVQVAEGLTLPQFLLKEEKDLRYCTK--HYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHK---------ELLRFRRKRKNKTEAFALEKFYRFSDMDDEVRESRFSFT----AYGMGPCLQAKDGMTPKGPNHPVQVMPKSPDEMRKVFIDRAKKIDTISRACFPLAFLIFNIFYWVIYKILRH 456
BLAST of Glycine receptor subunit alpha-3 vs. UniProt/SwissProt
Match: sp|O93430|GLRA1_DANRE (Glycine receptor subunit alphaZ1 OS=Danio rerio OX=7955 GN=glra1 PE=1 SV=1) HSP 1 Score: 258.84 bits (660), Expect = 1.795e-79 Identity = 145/402 (36.07%), Postives = 230/402 (57.21%), Query Frame = 1
Query: 274 TNVLVYMKVLAINSVSVTKMEYSTDVYLRQEWTDPRLTWENLEEFRSFNNNIVSPSLKKILWLPDLFFRNGKEGYVHKMTLPNYLMRLRPNGRILYSQKITMRFSCEMNLQTFPMDSQECLMDIGSYGYTLDELKFTWRKEDPILISTGLQISEFNSPHQVSTIDCTNDSSTSTGKYTCLKAKFLLQRQLGSYLVSTFVPSILIVMVSWLNFWINVDSVPARXXXXXXXXXXXXXQATGISSTLPRVSYIKAIDVWVIACIMFVIGALLEYVVASVLARKKKSNGWEKDVREIVRHELARWCSACQRQQFFHLQEQNTLDRNRLEFCSELESLLINHALDAHKGKKTIKTTPTEDSD------------------IDSYSRFLFPACFLLYNCFYWLYYLVL 1425
NV + + + S++ T M+Y +++LRQ+W DPRL + + ++ + PS+ +W PDLFF N K H++T N L+R+ NG +LYS +IT+ +C M+L+ FPMD Q C+M + S+GYT+++L F W ++ + ++ GL + +F + CT +TGK+TC++A+F L+RQ+G YL+ ++PS+LIV++SW++FWIN+D+ PARV LG+ T+L M TQ++G ++LP+VSY+KAID+W+ C++FV ALLEY + +AR+ K EL R+ QR++ HL+E D R F + A D K PT + ID+ SR FP FL++N FYW+ Y ++
Sbjct: 61 VNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPD----DSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCT--KHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARQHK--------------ELLRF----QRRRR-HLKEDEAGD-GRFSFAAYGMGPACLQAKDGMAIKGNNNNAPTSTNPPEKTVEEMRKLFISRAKRIDTVSRVAFPLVFLIFNIFYWITYKII 436
BLAST of Glycine receptor subunit alpha-3 vs. UniProt/SwissProt
Match: sp|P23416|GLRA2_HUMAN (Glycine receptor subunit alpha-2 OS=Homo sapiens OX=9606 GN=GLRA2 PE=1 SV=1) HSP 1 Score: 254.603 bits (649), Expect = 7.114e-78 Identity = 145/404 (35.89%), Postives = 229/404 (56.68%), Query Frame = 1
Query: 277 NVLVYMKVLAINSVSVTKMEYSTDVYLRQEWTDPRLTWENLEEFRSFNNNIVSPSLKKILWLPDLFFRNGKEGYVHKMTLPNYLMRLRPNGRILYSQKITMRFSCEMNLQTFPMDSQECLMDIGSYGYTLDELKFTWRKEDPILISTGLQISEFNSPHQVSTIDCTNDSSTSTGKYTCLKAKFLLQRQLGSYLVSTFVPSILIVMVSWLNFWINVDSVPARXXXXXXXXXXXXXQATGISSTLPRVSYIKAIDVWVIACIMFVIGALLEYVVASVLARKKKSNGWEKDVREIVRHELARWCSACQRQQFFHLQEQNTLDRNRLEFCSELESLLINHALDAHKGKKTIKTTPT-------EDSD------------IDSYSRFLFPACFLLYNCFYWLYYLVLVH 1431
NV + + + SV+ T M+Y +++LRQ+W D RL + + ++ + PS+ +W PDLFF N K H +T N L+R+ NG++LYS ++T+ SC M+L+ FPMD Q C M + S+GYT+++L F W + P+ ++ GL + +F + CT +TGK+TC++ KF L+RQ+G YL+ ++PS+LIV++SW++FWIN+D+ PARV LG+ T+L M TQ++G ++LP+VSY+KAID+W+ C++FV ALLEY + ++R+ K E R +RQ +E++ +R F + H L G +K TP +D D ID+ SR FP FL++N FYW+ Y ++ H
Sbjct: 72 NVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPD----DSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWLSDGPVQVAEGLTLPQFILKEEKELGYCTK--HYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQHK--------------EFLRLRRRQKRQN----KEEDVTRESRFNF----SGYGMGHCLQVKDG-TAVKATPANPLPQPPKDGDAIKKKFVDRAKRIDTISRAAFPLAFLIFNIFYWITYKIIRH 446
BLAST of Glycine receptor subunit alpha-3 vs. TrEMBL
Match: A0A3S5FGS1 (Uncharacterized protein OS=Protopolystoma xenopodis OX=117903 GN=PXEA_LOCUS33396 PE=3 SV=1) HSP 1 Score: 503.056 bits (1294), Expect = 2.461e-172 Identity = 249/412 (60.44%), Postives = 314/412 (76.21%), Query Frame = 1
Query: 199 RDLIMERIVDKKRYKKDERPSEIYQT--NVLVYMKVLAINSVSVTKMEYSTDVYLRQEWTDPRLTWENLEEFRSFNNNIVSPSLKKILWLPDLFFRNGKEGYVHKMTLPNYLMRLRPNGRILYSQKITMRFSCEMNLQTFPMDSQECLMDIGSYGYTLDELKFTWRKEDPILISTGLQISEFNSPHQVSTIDCTNDSSTSTGKYTCLKAKFLLQRQLGSYLVSTFVPSILIVMVSWLNFWINVDSVPARXXXXXXXXXXXXXQATGISSTLPRVSYIKAIDVWVIACIMFVIGALLEYVVASVLARKKKSNGWEKDVREIVRHELARWCSACQRQQFFHLQEQNTLDRNRLEFCSELESLLINHALDAHKGK-KTIKTTPTEDSDIDSYSRFLFPACFLLYNCFYWLYYLVL 1425
RD I+ I + Y K ERP+E+ T V V M+VLAI S+ V M+Y D YLRQ W D RL W +++EFR + IVS LK +WLPDLFFRNGKEGY+H MT+PNYL+R+ P+G +LYSQKITMRFSC+M LQ FPMD Q C ++IGSYGYTL+ELKF W E+ + +S ++ISEFN+P T DCTN S TSTG YTCL A F L+RQL SYL +T++P+ILI+MVSWL+FW+NVD+ PARV LGL++LLG+LTQA+ +S++LPRVSYIKAID+W+I I+FVIG L+EY +A + R+K+++ W +DVREIVR ELA+WC+ACQ+Q LQ + L R +LEFC ELE+LL N +D K K K +K T T +S+IDSYSRFLFPACFLLYNCFYWLYYLVL
Sbjct: 33 RDRIVNHIF--RNYLKHERPTELDNTPTEVGVNMRVLAIFSIDVRNMDYYIDAYLRQIWFDKRLAWAHIDEFRQYKQPIVSSKLKNDIWLPDLFFRNGKEGYLHTMTVPNYLLRVMPDGNVLYSQKITMRFSCQMELQNFPMDMQVCGLNIGSYGYTLNELKFVWH-EEKVNLSGRMRISEFNTPETFDTFDCTNSSKTSTGNYTCLNATFKLKRQLSSYLATTYIPNILIIMVSWLSFWVNVDAAPARVPLGLLSLLGILTQASSVSNSLPRVSYIKAIDIWMIFSIIFVIGVLVEYALALTMLRRKRADTWHRDVREIVRQELAKWCTACQQQHLVQLQNSHQLTRGQLEFCEELEALLTNQVIDHQKEKNKAVKPTTTTESEIDSYSRFLFPACFLLYNCFYWLYYLVL 441
BLAST of Glycine receptor subunit alpha-3 vs. TrEMBL
Match: A0A183AQU5 (Uncharacterized protein OS=Echinostoma caproni OX=27848 GN=ECPE_LOCUS9330 PE=3 SV=1) HSP 1 Score: 484.952 bits (1247), Expect = 2.079e-165 Identity = 243/413 (58.84%), Postives = 314/413 (76.03%), Query Frame = 1
Query: 199 RDLIMERIVDKKRYKKDERP-SEIYQTNVLVYMKVLAINSVSVTKMEYSTDVYLRQEWTDPRLTWENLEEFRSFNNNIVSPSLKKILWLPDLFFRNGKEGYVHKMTLPNYLMRLRPNGRILYSQKITMRFSCEMNLQTFPMDSQECLMDIGSYGYTLDELKFTWRKEDPILISTGLQISEFNSPHQVSTIDCTNDSSTSTGKYTCLKAKFLLQRQLGSYLVSTFVPSILIVMVSWLNFWINVDSVPARXXXXXXXXXXXXXQATGISSTLPRVSYIKAIDVWVIACIMFVIGALLEYVVASVLARKKKSNGWEKDVREIVRHELARWCSACQRQQFFHLQEQNTLDRNRLEFCSELESLLINHALDAHKGKKTIKTTPT-EDSDIDSYSRFLFPACFLLYNCFYWLYYLVLVH 1431
RD I+ I++K Y+ ERP + T+V+V+MK+LAI S+ V M+Y D+ LRQ W D RL+W + F+++ +VSP LK+ LWLPDLFFRNGK+GY+HK+TLPNYL+R+ PNG +LYSQKITMRFSC+M+LQTFPMD+Q+C+++IGSYGYT+ ELKF WR EDP+ ++ LQ+SEF +P T DC+ + STSTG Y CL+A F LQRQLGSYL +T+VP+ILI+MVSWL+FW+NVDS PARV LGL++LLG+LTQA +SSTLPRVSYIKAIDVW+I I+FVIG L+EY VA + RKK++ W +DV+ IV EL RWC+ CQ+QQ LQ L R +LEFC E+E LL + +D K K + P +S+ID+YSRFLFPAC++LYNCFYW YYL L H
Sbjct: 18 RDQIVNMIMNK--YRSYERPPTGANATHVIVFMKILAIFSIDVRTMDYYVDMLLRQTWKDRRLSWNEVPAFQNYTETLVSPKLKEQLWLPDLFFRNGKDGYLHKLTLPNYLLRVSPNGEVLYSQKITMRFSCQMHLQTFPMDTQKCMINIGSYGYTITELKFVWRAEDPVELADALQLSEFETPESFGTEDCSGNYSTSTGAYACLQAWFHLQRQLGSYLATTYVPNILIIMVSWLSFWVNVDSAPARVPLGLLSLLGILTQAISVSSTLPRVSYIKAIDVWMIFSIIFVIGVLVEYAVALTVLRKKQAETWHEDVKMIVHEELTRWCAVCQQQQLAQLQNSQGLSRGQLEFCEEMELLLTSQLIDDSKEKTKPRRPPGLVESEIDNYSRFLFPACYILYNCFYWAYYLGLKH 428
BLAST of Glycine receptor subunit alpha-3 vs. TrEMBL
Match: A0A5J4NN47 (Glycine receptor alpha-2 OS=Paragonimus westermani OX=34504 GN=DEA37_0005192 PE=3 SV=1) HSP 1 Score: 487.263 bits (1253), Expect = 1.256e-164 Identity = 237/412 (57.52%), Postives = 305/412 (74.03%), Query Frame = 1
Query: 199 RDLIMERIVDKKRYKKDERPSEIYQTNVLVY-MKVLAINSVSVTKMEYSTDVYLRQEWTDPRLTWENLEEFRSFNNNIVSPSLKKILWLPDLFFRNGKEGYVHKMTLPNYLMRLRPNGRILYSQKITMRFSCEMNLQTFPMDSQECLMDIGSYGYTLDELKFTWRKEDPILISTGLQISEFNSPHQVSTIDCTNDSSTSTGKYTCLKAKFLLQRQLGSYLVSTFVPSILIVMVSWLNFWINVDSVPARXXXXXXXXXXXXXQATGISSTLPRVSYIKAIDVWVIACIMFVIGALLEYVVASVLARKKKSNGWEKDVREIVRHELARWCSACQRQQFFHLQEQNTLDRNRLEFCSELESLLINHALDAHKGKKTIKTTPT-EDSDIDSYSRFLFPACFLLYNCFYWLYYLVLV 1428
RD I+E I+ K YK ERP E V+ MK+LAI S+ V M+Y D LRQ W D RL+W ++ F ++ +VSP LK+ LWLPDLFFRNGK+GY+H MTLPNYL+R+ PNG +LYSQKITMRFSC+M+LQTFPMD+Q C M+IGSYGYTL ELKF WR + P+ +S LQ+SEF +P + DC+ +SSTSTG+Y+CL A F LQRQLGSYL +T++P++LI+MVSWL+FW+NVDS PARV LGL++LLG+LTQA +SSTLPRVSYIKAIDVW++ I+FVIG L+EY VA + R+ W +DVR IV EL RWC+ CQ+QQ +Q L R +L FC E+E LL + +D +K K ++ P +S++D YSRF+FPA ++LYNCFYW+YYLVLV
Sbjct: 132 RDQIVEMIMSK--YKSYERPPEGGNATVVTMNMKILAIFSIDVRTMDYYVDALLRQTWKDRRLSWSDVPAFANYTQELVSPKLKEQLWLPDLFFRNGKDGYLHTMTLPNYLLRVSPNGEVLYSQKITMRFSCQMHLQTFPMDTQRCDMNIGSYGYTLSELKFVWRADKPVELSDNLQLSEFETPEEFEVADCSENSSTSTGQYSCLLATFELQRQLGSYLATTYIPNVLIIMVSWLSFWVNVDSAPARVPLGLLSLLGILTQAISVSSTLPRVSYIKAIDVWMMFSIIFVIGVLVEYAVALTVLRRNHQETWHQDVRHIVHEELTRWCAVCQQQQLSKIQNAQGLSRGQLGFCEEMELLLTSQLIDDNKEKSKLRRPPGLVESEVDRYSRFMFPASYILYNCFYWMYYLVLV 541
BLAST of Glycine receptor subunit alpha-3 vs. TrEMBL
Match: A0A183W0B4 (Uncharacterized protein OS=Trichobilharzia regenti OX=157069 GN=TRE_LOCUS6169 PE=3 SV=1) HSP 1 Score: 486.108 bits (1250), Expect = 6.055e-164 Identity = 247/416 (59.38%), Postives = 313/416 (75.24%), Query Frame = 1
Query: 190 AQQRDLIMERIVDKKRYKKDERPSEIYQ-TNVLVYMKVLAINSVSVTKMEYSTDVYLRQEWTDPRLTWENLEEFRSFNNNIVSPSLKKILWLPDLFFRNGKEGYVHKMTLPNYLMRLRPNGRILYSQKITMRFSCEMNLQTFPMDSQECLMDIGSYGYTLDELKFTWRKEDPILISTGLQISEFNSPHQVSTIDCTNDSSTSTGKYTCLKAKFLLQRQLGSYLVSTFVPSILIVMVSWLNFWINVDSVPARXXXXXXXXXXXXXQATGISSTLPRVSYIKAIDVWVIACIMFVIGALLEYVVASVLARKKKSNGWEKDVREIVRHELARWCSACQRQQFFHLQEQNTLDRNRLEFCSELESLLINHALDAHKGKKTIKTTPT-EDSDIDSYSRFLFPACFLLYNCFYWLYYLVLVH 1431
+ RD I+ I+ K Y+ ERP + T V V MKVLAI S+ V M+Y+ D+ LRQ W D RL+W + EFR F +VSP LK+ LWLPDLFFRNGK+GY+HK+TLPNYL+R+ PNG +LYSQKITMRFSC+M+LQTFPMDSQ C +DIGSYGYTL+ELKF W E P+ + LQ+SEF +P + DC++ STSTG+Y CLKA F LQRQLGSYL +T+VP++LI+MVSWL+FW+NVDS PARV LGL++LLG+LTQA +SSTLPRVSYIKAID+W+I I+FVIG L+EY VA L R+K+S W +DV++IVR ELARWC+ CQ+QQ LQ L R ++EF ELE LL N ++ K K + P +S++D+YSRFLFPACF+LYNCFYW Y+LV+V+
Sbjct: 138 SSMRDRIVSLIMSK--YRSYERPPDGGNATIVTVNMKVLAIFSIDVRTMDYNVDLLLRQAWRDRRLSWHEIPEFRDFKEPLVSPKLKEQLWLPDLFFRNGKDGYLHKLTLPNYLLRVHPNGNVLYSQKITMRFSCQMHLQTFPMDSQSCYIDIGSYGYTLNELKFVWNGEKPVELGENLQLSEFETPEKFDAHDCSSGYSTSTGQYACLKATFELQRQLGSYLATTYVPNVLIIMVSWLSFWVNVDSAPARVPLGLLSLLGILTQAISVSSTLPRVSYIKAIDIWMIFSIIFVIGVLVEYAVALTLLRRKQSETWHEDVKDIVREELARWCAICQQQQLVQLQNSQGLTRGQMEFREELEHLLTNQLIEESKDKSKPRRPPGLVESEVDTYSRFLFPACFVLYNCFYWCYFLVIVN 551
BLAST of Glycine receptor subunit alpha-3 vs. TrEMBL
Match: A0A183PWS9 (Uncharacterized protein OS=Schistosoma mattheei OX=31246 GN=SMTD_LOCUS18815 PE=3 SV=1) HSP 1 Score: 481.485 bits (1238), Expect = 5.426e-163 Identity = 247/413 (59.81%), Postives = 316/413 (76.51%), Query Frame = 1
Query: 199 RDLIMERIVDKKRYKKDERPSEIYQ-TNVLVYMKVLAINSVSVTKMEYSTDVYLRQEWTDPRLTWENLEEFRSFNNNIVSPSLKKILWLPDLFFRNGKEGYVHKMTLPNYLMRLRPNGRILYSQKITMRFSCEMNLQTFPMDSQECLMDIGSYGYTLDELKFTWRKEDPILISTGLQISEFNSPHQVSTIDCTNDSSTSTGKYTCLKAKFLLQRQLGSYLVSTFVPSILIVMVSWLNFWINVDSVPARXXXXXXXXXXXXXQATGISSTLPRVSYIKAIDVWVIACIMFVIGALLEYVVASVLARKKKSNGWEKDVREIVRHELARWCSACQRQQFFHLQEQNTLDRNRLEFCSELESLLINHALDAHKGKKTIKTTPTE-DSDIDSYSRFLFPACFLLYNCFYWLYYLVLVH 1431
RD I+ I+ K Y+ ERP + T V V MKVLAI S+ V M+Y D+ LRQ W D RL+W ++ EF FN +VSP LK+ LWLPDLFFRNGK+GY+HK+TLPNYL+R+ PNG +LYSQKITMRFSC+M+LQTFPMD+Q C ++IGSYGYTL+ELKF W + P+ ++ LQ+SEF +P Q T DC++ STSTG+YTCL A F LQRQLGSYL +T++P++LI+MVSWL+FW+NVDS PARV LGL++LLG+LTQA +SSTLPRVSYIKAID+W+I I+FVIG L+EY +A + R+K+S W +DV+EIVR ELARWC+ CQ+QQ LQ N L + +LEF ELE LL N +D +K K K P +S+ID+YSRFLFPACF+LYNCFYW Y+L++V+
Sbjct: 93 RDRIVNLIMSK--YRSYERPPDGGNATIVTVNMKVLAIFSIDVRTMDYYIDLLLRQVWRDRRLSWYDIPEFSKFNEPLVSPKLKEQLWLPDLFFRNGKDGYLHKLTLPNYLLRVHPNGNVLYSQKITMRFSCQMHLQTFPMDNQHCHINIGSYGYTLNELKFVWNHDKPVELAEKLQLSEFETPKQFITNDCSSGYSTSTGQYTCLNATFELQRQLGSYLATTYIPNVLIIMVSWLSFWVNVDSAPARVPLGLLSLLGILTQAISVSSTLPRVSYIKAIDIWMIFSIIFVIGVLVEYAIALTILRRKQSETWHEDVKEIVREELARWCAICQQQQLIQLQNTNQLIKGQLEFREELEHLLTNQFIDDYKDKTKPKRPPGLIESEIDTYSRFLFPACFVLYNCFYWCYFLIIVN 503
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Cavefish
Match: glra1 (glycine receptor alpha 1 [Source:NCBI gene;Acc:103026517]) HSP 1 Score: 258.07 bits (658), Expect = 4.739e-80 Identity = 147/418 (35.17%), Postives = 233/418 (55.74%), Query Frame = 1
Query: 226 DKKRYKKDERPSEIYQTNVLVYMKVLAINSVSVTKMEYSTDVYLRQEWTDPRLTWENLEEFRSFNNNIVSPSLKKILWLPDLFFRNGKEGYVHKMTLPNYLMRLRPNGRILYSQKITMRFSCEMNLQTFPMDSQECLMDIGSYGYTLDELKFTWRKEDPILISTGLQISEFNSPHQVSTIDCTNDSSTSTGKYTCLKAKFLLQRQLGSYLVSTFVPSILIVMVSWLNFWINVDSVPARXXXXXXXXXXXXXQATGISSTLPRVSYIKAIDVWVIACIMFVIGALLEYVVASVLARKKKSNGWEKDVREIVRHELARWCSACQRQQFFHLQEQNTLDRNRLEFCSELESLLINHALDAHKGKKTIKTTPTED------------------SDIDSYSRFLFPACFLLYNCFYWLYYLVL 1425
D + K D + NV + + + S++ T M+Y +++LRQ+W DPRL + + ++ + PS+ +W PDLFF N K H++T N L+R+ NG +LYS +IT+ +C M+L+ FPMD Q C+M + S+GYT+++L F W ++ + ++ GL + +F + CT +TGK+TC++A+F L+RQ+G YL+ ++PS+LIV++SW++FWIN+D+ PARV LG+ T+L M TQ++G ++LP+VSY+KAID+W+ C++FV ALLEY + +AR+ K EL R+ QR++ HL+E R F + A D K PT ID+ SR FP FL++N FYW+ Y ++
Sbjct: 61 DPQGSKSDGTHKKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPD----DSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTK--HYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARQHK--------------ELLRF----QRRR-RHLKEDEA-GEGRFSFAAYGMGPACLQAKDGMAIKGNNNNAPTSSIPPEKTVEEMRKLFISRAKRIDTVSRVAFPLVFLIFNIFYWIIYKII 452
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Cavefish
Match: glra1 (glycine receptor alpha 1 [Source:NCBI gene;Acc:103026517]) HSP 1 Score: 256.914 bits (655), Expect = 9.122e-80 Identity = 144/402 (35.82%), Postives = 228/402 (56.72%), Query Frame = 1
Query: 274 TNVLVYMKVLAINSVSVTKMEYSTDVYLRQEWTDPRLTWENLEEFRSFNNNIVSPSLKKILWLPDLFFRNGKEGYVHKMTLPNYLMRLRPNGRILYSQKITMRFSCEMNLQTFPMDSQECLMDIGSYGYTLDELKFTWRKEDPILISTGLQISEFNSPHQVSTIDCTNDSSTSTGKYTCLKAKFLLQRQLGSYLVSTFVPSILIVMVSWLNFWINVDSVPARXXXXXXXXXXXXXQATGISSTLPRVSYIKAIDVWVIACIMFVIGALLEYVVASVLARKKKSNGWEKDVREIVRHELARWCSACQRQQFFHLQEQNTLDRNRLEFCSELESLLINHALDAHKGKKTIKTTPTED------------------SDIDSYSRFLFPACFLLYNCFYWLYYLVL 1425
NV + + + S++ T M+Y +++LRQ+W DPRL + + ++ + PS+ +W PDLFF N K H++T N L+R+ NG +LYS +IT+ +C M+L+ FPMD Q C+M + S+GYT+++L F W ++ + ++ GL + +F + CT +TGK+TC++A+F L+RQ+G YL+ ++PS+LIV++SW++FWIN+D+ PARV LG+ T+L M TQ++G ++LP+VSY+KAID+W+ C++FV ALLEY + +AR+ K EL R+ QR++ HL+E R F + A D K PT ID+ SR FP FL++N FYW+ Y ++
Sbjct: 64 VNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPD----DSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTK--HYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARQHK--------------ELLRF----QRRR-RHLKEDEA-GEGRFSFAAYGMGPACLQAKDGMAIKGNNNNAPTSSIPPEKTVEEMRKLFISRAKRIDTVSRVAFPLVFLIFNIFYWIIYKII 439
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Cavefish
Match: glra3 (glycine receptor, alpha 3 [Source:ZFIN;Acc:ZDB-GENE-020402-1]) HSP 1 Score: 255.373 bits (651), Expect = 4.621e-79 Identity = 144/404 (35.64%), Postives = 233/404 (57.67%), Query Frame = 1
Query: 277 NVLVYMKVLAINSVSVTKMEYSTDVYLRQEWTDPRLTWENLEEFRSFNNNIVSPSLKKILWLPDLFFRNGKEGYVHKMTLPNYLMRLRPNGRILYSQKITMRFSCEMNLQTFPMDSQECLMDIGSYGYTLDELKFTWRKEDPILISTGLQISEFNSPHQVSTIDCTNDSSTSTGKYTCLKAKFLLQRQLGSYLVSTFVPSILIVMVSWLNFWINVDSVPARXXXXXXXXXXXXXQATGISSTLPRVSYIKAIDVWVIACIMFVIGALLEYVVASVLARKKKS-----NGWEKDVREIVRHELARWCSACQRQQFFHLQEQNTLDRNRLEFCSELESLLINHALDAHKGKKTIKTTP-----TED---------SDIDSYSRFLFPACFLLYNCFYWLYYLVLVH 1431
NV + + + S++ T M+Y +++LRQ+W DPRL + + ++ + PS+ +W PDLFF N K + H++T N L+R+ NG +LYS ++T+ SC M+L+ FPMD Q C+M + S+GYT+++L F W+ P+ ++ GL + +F + CT +TGK+TC++ +F L+RQ+G YL+ ++PS+LIV++SW++FWIN+D+ PARV LG+ T+L M TQ++G ++LP+VSY+KAID+W+ C++FV ALLEY + ++R+ K +K +E E+ C + + + T+ + N+A KG+ T T P TE+ ID+ SR FP FL +N FYW+ Y +L H
Sbjct: 70 NVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPD----DSLDLDPSMLDSIWKPDLFFANEKGAHFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQANGPVQVADGLTLPQFILKDESDLRYCTKH--YNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRTSLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRRRKKSTKE---EEVRESCLSFTA----NAGKDGTMTKP------------TNNAASTPKGQPT-PTVPQAGKSTEEMRKIFIDRAKKIDTVSRAGFPLAFLFFNIFYWVLYKILRH 447
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Cavefish
Match: glra3 (glycine receptor, alpha 3 [Source:ZFIN;Acc:ZDB-GENE-020402-1]) HSP 1 Score: 256.144 bits (653), Expect = 7.144e-79 Identity = 145/424 (34.20%), Postives = 236/424 (55.66%), Query Frame = 1
Query: 277 NVLVYMKVLAINSVSVTKMEYSTDVYLRQEWTDPRLTWENLEEFRSFNNNIVSPSLKKILWLPDLFFRNGKEGYVHKMTLPNYLMRLRPNGRILYSQKITMRFSCEMNLQTFPMDSQECLMDIGSYGYTLDELKFTWRKEDPILISTGLQISEFNSPHQVSTIDCTNDSSTSTGKYTCLKAKFLLQRQLGSYLVSTFVPSILIVMVSWLNFWINVDSVPARXXXXXXXXXXXXXQATGISSTLPRVSYIKAIDVWVIACIMFVIGALLEYVVASVLARKKK----------------SNGWEKDVREIVRHELARWCSACQRQQFFHLQEQNTLDRNRLEFCSELESLL---------INHALDAHKGKKTIKTTP-----TED---------SDIDSYSRFLFPACFLLYNCFYWLYYLVLVH 1431
NV + + + S++ T M+Y +++LRQ+W DPRL + + ++ + PS+ +W PDLFF N K + H++T N L+R+ NG +LYS ++T+ SC M+L+ FPMD Q C+M + S+GYT+++L F W+ P+ ++ GL + +F + CT +TGK+TC++ +F L+RQ+G YL+ ++PS+LIV++SW++FWIN+D+ PARV LG+ T+L M TQ++G ++LP+VSY+KAID+W+ C++FV ALLEY + ++R+ K +E+++ E ++ + + E N + E C + N+A KG+ T T P TE+ ID+ SR FP FL +N FYW+ Y +L H
Sbjct: 70 NVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPD----DSLDLDPSMLDSIWKPDLFFANEKGAHFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQANGPVQVADGLTLPQFILKDESDLRYCTK--HYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRTSLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRRRKKSTKLHDRSFEEELSESLQSVNGLRSADPVYGSMDQMSESNDREEEVRESCLSFTANAGKDGTMTKPTNNAASTPKGQPT-PTVPQAGKSTEEMRKIFIDRAKKIDTVSRAGFPLAFLFFNIFYWVLYKILRH 486
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Cavefish
Match: glra2 (glycine receptor, alpha 2 [Source:ZFIN;Acc:ZDB-GENE-090407-1]) HSP 1 Score: 254.218 bits (648), Expect = 9.156e-79 Identity = 146/403 (36.23%), Postives = 234/403 (58.06%), Query Frame = 1
Query: 277 NVLVYMKVLAINSVSVTKMEYSTDVYLRQEWTDPRLTWENLEEFRSFNNNIVSPSLKKILWLPDLFFRNGKEGYVHKMTLPNYLMRLRPNGRILYSQKITMRFSCEMNLQTFPMDSQECLMDIGSYGYTLDELKFTWRKEDPILISTGLQISEFNSPHQVSTIDCTNDSSTSTGKYTCLKAKFLLQRQLGSYLVSTFVPSILIVMVSWLNFWINVDSVPARXXXXXXXXXXXXXQATGISSTLPRVSYIKAIDVWVIACIMFVIGALLEYVVASVLARKKKSNGWEKDVREIVRHELARWCSACQRQQFFHLQEQNTLDRNRLEF-------CSELESLLINHALDA-----------HKGKKTIKTTPTEDSDIDSYSRFLFPACFLLYNCFYWLYYLVLVH 1431
NV + + + SV+ T M+Y +++LRQ+W DPRL + + S + + PS+ +W PDLFF N K H +T N L+R+ +G +LYS ++T+ SC M+L+ FPMD Q C M + S+GYT+++L F W E P+ ++ GL + +F + CT +TGK+TC++ KF L+RQ+G YL+ ++PS+LIV++SW++FWIN+D+ PARV LG+ T+L M TQ++G ++LP+VSY+KAID+W+ C++FV ALLEY + ++R++K E +R +R+Q +L+E+ L R F C + +++ + +A H KK + ID+ SR FP FL++N FYW+ Y ++ H
Sbjct: 60 NVTCNIFINSFGSVTETTMDYRVNIFLRQKWNDPRLAYSEYPD-PSLD---LDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKDGTVLYSIRLTLILSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWLDEGPVQVAEGLTLPQFIMREEKELGYCTK--HYNTGKFTCIEVKFKLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAGVNFVSRQQK---------EFLR---------LKRRQKRNLKEE--LREGRFHFSGYSMAPCMKDGTVVKSATANAIQQPSALRDAEHNRKKFVDRA----KRIDTISRAAFPLAFLIFNIFYWITYKIIRH 432
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Sea Lamprey
Match: glra2 (glycine receptor, alpha 2 [Source:ZFIN;Acc:ZDB-GENE-090407-1]) HSP 1 Score: 250.366 bits (638), Expect = 1.357e-78 Identity = 141/399 (35.34%), Postives = 231/399 (57.89%), Query Frame = 1
Query: 268 YQTNVLVYMKVLAINSVSVTKMEYSTDVYLRQEWTDPRLTWENLEEFRSFNNNIVSPSLKKILWLPDLFFRNGKEGYVHKMTLPNYLMRLRPNGRILYSQKITMRFSCEMNLQTFPMDSQECLMDIGSYGYTLDELKFTWRKEDPILISTGLQISEFNSPHQVSTIDCTNDSSTSTGKYTCLKAKFLLQRQLGSYLVSTFVPSILIVMVSWLNFWINVDSVPARXXXXXXXXXXXXXQATGISSTLPRVSYIKAIDVWVIACIMFVIGALLEYVVASVLARKKKSNGWEKDVREIVRHELARWCSACQRQQFFHLQEQNTLDRNRLEFCSELESLLINHALDAHKG-------------KKTIKTTPTEDSD-IDSYSRFLFPACFLLYNCFYWLYYLV 1422
Y NV + + + S++ T M+Y +++LRQ+W DPRL + + ++ + PS+ +W PDLFF N K H++T N L+R+ +G +LYS ++T+ SC M+L+ FPMD Q C M + S+GYT+++L F W++E + ++ GL + +F + + CT +TGK+TC++ KF L+RQ+G YL+ ++PS+LIV++SW++FWIN+D+ PARV LG+ T+L M TQ++G ++LP+VSY+KAID+W+ C++FV ALLEY + ++R+ K + R+ + +L C F + + N + E L ++ KG + IK + + ID+ SR FP FL++N FYW+ Y V
Sbjct: 4 YPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPD----DSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKDGNVLYSIRLTLTLSCPMDLKNFPMDVQTCAMQLESFGYTMNDLIFEWKQEGAVQVAEGLTLPQFVLKDEKDLVYCTK--HYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQHKELLRIRRRRQRNQIDLTSLILIC--NIFTYFINSSVPIFNMFKRVEGNERALTKDSVSV-KGVNATNAAPAPAPTQDAIKKKFVDRAKRIDTISRAAFPLAFLIFNIFYWIIYKV 393
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008467.1 (pep scaffold:Pmarinus_7.0:GL477211:8305:20106:1 gene:ENSPMAG00000007648.1 transcript:ENSPMAT00000008467.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 241.891 bits (616), Expect = 1.856e-74 Identity = 146/409 (35.70%), Postives = 226/409 (55.26%), Query Frame = 1
Query: 277 NVLVYMKVLAINSVSVTKMEYSTDVYLRQEWTDPRLTWEN--LEEFRSFNNNIVSPSLKKILWLPDLFFRNGKEGYVHKMTLPNYLMRLRPNGRILYSQKITMRFSCEMNLQTFPMDSQECLMDIGSYGYTLDELKFTWRKEDPILISTGLQISEFNSPHQVSTIDCTNDSSTSTGKYTCLKAKFLLQRQLGSYLVSTFVPSILIVMVSWLNFWINVDSVPARXXXXXXXXXXXXXQATGISSTLPRVSYIKAIDVWVIACIMFVIGALLEYVVASVLARK-----KKSNGWEKDVREIVRHELARWCSACQRQQFFHLQEQNTLDRNRLEFCSELESLLINHALDAHKGKKTI------------------KTTPTEDSDIDSYSRFLFPACFLLYNCFYWLYYLVLV 1428
NV + + + S+ +Y VYLRQ WTDPRL + + + +NI K +W PDLFF N K + H++T N ++R+ NG + Y+ ++T+ SC M+L FPMD+Q C M + S+GYT ++ F W P+ + GL + +F +++ST CT + STG +TC+ AKF L R++G YL+ +VPSILIV++SW++FWIN+++ PARV LG+ T+L + TQ+TG ++LP+VSYIKA+D+W+ C++FV ALLEY +V +R+ KK G +K + +++ H+ W +F + N L L F + +L N L KK + K ID+ SR FP FL++N YW + V++
Sbjct: 70 NVSCGVFIRSFGSIQEATSDYRMTVYLRQRWTDPRLAYSHYPVPLLHLDQSNI------KHIWKPDLFFDNEKSAHFHEITTDNKMLRIANNGVVDYAMRLTLTLSCPMDLHNFPMDTQMCSMYLESFGYTTADIVFHWNGPTPVSLFEGLTLPQFVLSNKISTGSCTK--TYSTGSFTCIFAKFTLHREMGFYLIQLYVPSILIVILSWVSFWINMEAAPARVALGITTVLTLTTQSTGARASLPKVSYIKAMDIWMATCLLFVFAALLEYAAVNVTSRQSQGFMKKGRGNQKPI-DLLVHKKMFW-------KFLVAENDNDL----LYFTITIFTL--NGLLPVSDSKKPVIVCIKPLLSLQETKEKMRKKYVACAQTIDNISRLFFPISFLIFNVVYWFAFKVML 456
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Sea Lamprey
Match: glra1 (glycine receptor, alpha 1 [Source:NCBI gene;Acc:30676]) HSP 1 Score: 202.601 bits (514), Expect = 1.092e-61 Identity = 100/248 (40.32%), Postives = 165/248 (66.53%), Query Frame = 1
Query: 277 NVLVYMKVLAINSVSVTKMEYSTDVYLRQEWTDPRLTWENLEE-FRSFNNNIVSPSLKKILWLPDLFFRNGKEGYVHKMTLPNYLMRLRPNGRILYSQKITMRFSCEMNLQTFPMDSQECLMDIGSYGYTLDELKFTWRKEDPILISTGLQISEFNSPHQVSTIDCTNDSSTSTGKYTCLKAKFLLQRQLGSYLVSTFVPSILIVMVSWLNFWINVDSVPARXXXXXXXXXXXXXQATGISSTLPRVS 1017
N VY+K + S+ T M+Y ++LRQ+W DPRLT+ + E + + + + + +W PDLFF N K Y H++T N ++R+ NG +L++ ++T+ SC M+L+ FPMD+Q C M + S+GYT+ +L F W +E+P++IS L + +F ++ T C S+ TG ++C+ A+F+L R++G YL+ +VPS LIV++SW++FWIN+++ PARV LG+ T+L M TQ+TG ++LP+V+
Sbjct: 33 NCSVYIK--SFGSIEETTMDYQVTIFLRQKWIDPRLTYSHYPEPYLDLDQSNI-----QYIWRPDLFFDNEKSAYFHEVTTDNKMLRIFKNGLVLFTVRLTLTLSCPMDLRNFPMDTQMCYMFLESFGYTMADLSFHWDEEEPVIISKELVLPQFVLSSKIDTDSCDKLYSSGTGHFSCISARFVLHREMGFYLIQLYVPSALIVIISWVSFWINMEAAPARVALGITTVLTMTTQSTGARASLPKVT 273
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Sea Lamprey
Match: glra4a (glycine receptor, alpha 4a [Source:ZFIN;Acc:ZDB-GENE-010410-3]) HSP 1 Score: 201.06 bits (510), Expect = 4.874e-59 Identity = 129/428 (30.14%), Postives = 215/428 (50.23%), Query Frame = 1
Query: 175 RKSPMAQQRDLIMERIVDKKRYKKDERPSEIYQTNVLVYMKVLAINSVSVTKMEYSTDVYLRQEWTDPRLTWENLEEFRSFNNNIV--SPSLKKILWLPDLFFRNGKEGYVHKMTLPN---YLMRLRPNGRILYSQKITMRFSCEMNLQTFPMDSQECLMDIGSYGYTLDELKFTWRKEDPILISTGLQISEFNSPHQVSTIDCTNDSSTSTGKYTCLKAKFLLQRQLGSYLVSTFVPSILIVMVSWLNFWINVDSVPARXXXXXXXXXXXXXQATGISSTLPRVSYIKAIDVWVIACIMFVIGALLEYVVASVLARKKKSNGWEKDVREIVRHELA-RW-------CSACQRQQFFHLQEQNTLDRNRLEFCSELESLLINHALDAHKGKKTIK-TTPTEDSDIDSYSRFLFPACFLLYNCFYWLYY 1416
+ SP ++I + D + + P + ++LV V M+YS +++LRQ W DPR+ N+ + +N + + S +W PDLFF N K L Y+ ++++ +C M+L+ +PMD+Q C + + SYGYT ++L F W +P+ G+ +F ++ +CT + + G ++C+KA F L R +G YL+ ++PS L+V++SWL+FW+NV++ PARV LG+ T+L + TQ T ++ LP+VSYIKAIDVW+ AC +FV ALLE+ ++ R+ + D + EL W S+ +R Q H E++ + + N+A H + + + ID SR +FP F+++N FYW+ Y
Sbjct: 40 KPSPFLSMDNVIRDTGYDSRMRPNVDGPPVVVNCSILV----KGFGPVEEATMDYSINIFLRQTWNDPRIL--NVLKSIEYNTDFLDLGNSFVDSVWKPDLFFENEKSAAFQMYQLVTGFKYMYTFAMWITCFLCFRLSLVLACPMSLEVYPMDAQYCSIYLESYGYTTNDLIFQWNDTEPVSFGAGVSTPKFTLSNETFLGECTKE--YTYGTFSCVKATFFLDRDMGYYLIQVYIPSCLLVIISWLSFWLNVEAAPARVGLGITTILTVTTQMTSANAALPKVSYIKAIDVWMGACQVFVFSALLEFAAVNMATRRHGISPSHHDGDHGTKGELPIEWKRHRHANVSSVRRPQ-RHRPERDCRSQGKPGVFHTNSRRDENNATRVHVSDEEWRYQSLLHARRIDYISRVIFPTVFMIFNIFYWVIY 458
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002305.1 (pep scaffold:Pmarinus_7.0:GL478144:76380:93696:1 gene:ENSPMAG00000002075.1 transcript:ENSPMAT00000002305.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 199.904 bits (507), Expect = 7.638e-59 Identity = 127/436 (29.13%), Postives = 222/436 (50.92%), Query Frame = 1
Query: 193 QQRDLI-------MERIVDKKRYKKDERPSEIYQTNVLVYMKVL--AINSVSVTKMEYSTDVYLRQEWTDPRL-----TWENLEEFRSFNNNIVSPSLKKILWLPDLFFRNGKEGYVHKMTLPNYLMRLRPNGRILYSQKITMRFSCEMNLQTFPMDSQECLMDIGSYGYTLDELKFTWRKEDPILISTGLQISEFNSPHQVSTIDCTNDSSTSTGKYTCLKAKFLLQRQLGSYLVSTFVPSILIVMVSWLNFWINVDSVPARXXXXXXXXXXXXXQATGISSTLPRVSYIKAIDVWVIACIMFVIGALLEYVVASVLAR-----------KKKSNGWE---KDVREIVRHELARWCSACQRQQFFHLQEQNTLDRNRLEFCSELESLLINHALDAHKGKKTIKTTPTEDSDIDSYSRFLFPACFLLYNCFYWLYY 1416
Q+RD++ ++ ++ + Y RP+ +Y + VLV VL + + M+Y +YL+Q W D R+ ++F NN + +W PDLFF N K H++ ++ N + +S +++ +C MNL+ +P+D+QEC +++ S+GYT +L F W + +P++++T L +F + DC+ + TG ++C+ A F L R +G YL+ + PS L+V++SWL+FW++V+S PARV+LG+ T+L + TQ T ++ LP++SYIKA+DVW+ AC +FV ALLE V SV + +K +N W+ + ++V + +R ++ ++ I+ D+ + + + ID SR LFP F+++ YW Y
Sbjct: 22 QRRDIVKRSGMDGLDELIKESSYDGRLRPN-MYGSPVLVNCSVLVKSFGPIEENTMDYMMLIYLQQSWIDSRIESIYSAGHYQKDFLDLANNYI-----DTVWTPDLFFENEKSAAFHEIHCRFSIIVHATNNKTCFSLVLSLTLACPMNLEYYPLDTQECRINLESFGYTTQDLIFQWDENEPLVVATNLYTPKFKLSNHTELGDCSKE--YLTGTHSCINATFYLHRDMGYYLIQVYFPSCLLVIISWLSFWLSVESTPARVSLGITTILTVTTQMTSANAALPKMSYIKAMDVWMAACQVFVFAALLESTVVSVTKQHVVSGKAETRDQKNNNVWDLFFNPLYDVVGYNRSRSLGRAAKRT--------------TSVVNQPHGWFISQPTDSDGMAR--ERSLVRSRQIDYISRVLFPLAFVIFLTIYWFSY 433
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Nematostella
Match: EDO39173 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SAS4]) HSP 1 Score: 183.726 bits (465), Expect = 4.393e-54 Identity = 101/271 (37.27%), Postives = 170/271 (62.73%), Query Frame = 1
Query: 277 NVLVYMKVLAINSVSVTKMEYSTDVYLRQEWTDPRLTWENLEEFRSFNNNIVSPSLKKILWLPDLFFRNGKEGYVHKMTLPNYLMRLRPNGRILYSQKITMRFSCEMNLQTFPMDSQECLMDIGSYGYTLDELKFTWRKEDPILISTGLQISEFNSPHQVSTIDCTNDSSTSTGKYTCLKAKFLLQRQLGSYLVSTFVPSILIVMVSWLNFWINVDSVPARXXXXXXXXXXXXXQATGISSTLPRVSYIKAIDVWVIACIMFVIGALLEYV 1089
N+ VYM V++ ++V ME+S DV+ +Q W DPRL F I+ S K+ W+PD FF N K H++ N + + P+G I S+++T+ SC M+L+ +P+D Q C+++I SY + ++++ + W+ ++ ++I G +++EF + S + S + TG YT L AKF+ +R+L + + P+ LIV++SWL+FWI+ D+VPARV LG+ T+L ++T + +++P+VSYIKAID+++I +FV G LLEY+
Sbjct: 30 NISVYMSVVSFSTVYEKDMEFSLDVFFKQAWRDPRLRHSAKMPF------ILPGSQKEKFWIPDTFFLNVKTARFHQVPAANTRIVVTPDGDIELSERLTVSASCRMDLRMYPLDQQTCVLEILSYSFDINDIDYRWKAKEDLIILDG-EMNEFE--LKDSRGERKQKSRSCTGTYTHLVAKFVFRRRLAYSFIQIYSPTFLIVVLSWLSFWISKDAVPARVALGITTVLTIVTLMGSLRNSVPKVSYIKAIDLYLIVSFIFVFGTLLEYI 291
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Nematostella
Match: EDO34692 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SNK5]) HSP 1 Score: 182.185 bits (461), Expect = 1.202e-53 Identity = 101/281 (35.94%), Postives = 171/281 (60.85%), Query Frame = 1
Query: 337 YSTDVYLRQEWTDPRLTWENLEEFRSFNNNIVSPSLKKI--LWLPDLFFRNGKEGYVHKMTLPNYLMRLRPNGRILYSQKITMRFSCEMNLQTFPMDSQECLMDIGSYGYTLDELKFTWRKE----DPILISTGLQISEFNSPHQVSTIDCTNDSST-STGKYTCLKAKFLLQRQLGSYLVSTFVPSILIVMVSWLNFWINVDSVPARXXXXXXXXXXXXXQATGISSTLPRVSYIKAIDVWVIACIMFVIGALLEYVVASVLARKKKSNGWEKDVREIVR 1158
++ D+YLRQ W DPRL ++ + N ++++ + + I +W+P +F N K+ Y H +T NYL+ ++PNG + YS ++T+ +C++ LQ FP D Q C M + SYGY ++ + W D + IS L++ +F +++ + ++ + G ++ L AKF R+LG Y++ T++PS+L V +SW +FWI+ DS PARV LG+ T+L M+T + + LP+VSY KAID +++ C+++V GAL+EY + + A K + K RE +R
Sbjct: 2 FTIDMYLRQYWRDPRLIFDPV----PVNTDVLTLNRQTIDEIWIPSTYFFNAKKAYFHDVTTENYLLMIKPNGDVFYSVRLTITMACKLTLQMFPHDVQVCEMMLESYGYQATDVYYRWNSRNSTGDVVYISEDLEMPQF----KITNVKLEERTNIYNIGPHSALIAKFTFHRRLGYYMIQTYIPSMLTVTISWFSFWISPDSPPARVGLGITTVLTMITISNSARAPLPKVSYTKAIDWFLLMCLVYVFGALMEYAIVNFYACKVQQRNRNK--REEIR 272
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Nematostella
Match: EDO41538 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S448]) HSP 1 Score: 182.185 bits (461), Expect = 1.051e-52 Identity = 121/382 (31.68%), Postives = 197/382 (51.57%), Query Frame = 1
Query: 334 EYSTDVYLRQEWTDPRLTWENLEEFRSFNNNIVSPSLKKILWLPDLFFRNGKEGYVHKMTLPNYLMRLRPNGRILYSQKITMRFSCEMNLQTFPMDSQECLMDIGSYGYTLDELKFTW--RKEDPILISTGLQISEFNSPHQVSTIDCTNDSSTSTGKYTCLKAKFLLQRQLGSYLVSTFVPSILIVMVSWLNFWINVDSVPARXXXXXXXXXXXXXQATGISSTLPRVSYIKAIDVWVIACIMFVIGALLEYVVA--------SVLARK---------KKSNGWEKDVREI-VRHELARWCSACQRQQFFHLQEQNTLDRNRLEFCSELESLLINHALDAHKGKKTIKTTPTEDSDIDSYSRFLFPACFLLYNCFYWLYYL 1419
+YS D++ RQ W D RL + + F N +P + W PD +F N K H +T N ++ P+G I YS +IT+ SCEM+L+ FPMD+Q+C++ I SY YT++++ + W R PI I G ++++F+ T+ S TG + L+ F +R+ ++V +VPS IV +SWL FWIN ++VPAR++L + +L + I+S+LPR+SY+KA+D ++I MF++ +++EYV+ L+RK ++SNG + RE+ V + + L +++ F +L S + H KK+ ID S+ +FP + L+N YW YYL
Sbjct: 4 DYSLDIFFRQWWRDERLAHDVNKVF----NMAANPG--QYFWTPDTYFVNVKSSKFHHVTRENMRTKIWPDGLIYYSSRITLTASCEMDLRFFPMDTQDCVLKIESYAYTVEDVIYNWNNRGTTPIEIFAG-EMAQFDMTEM--TMQTMITFSLLTGSFDSLRVSFRFKRRTSYFIVQHYVPSAFIVFLSWLGFWINKNAVPARISLTVTCILSTMVLFESINSSLPRISYLKAVDYYLIISFMFILASMVEYVLVLNVTDYKRITLSRKHSLQPCHCRERSNGLPRPRRELPVPNGFSDADHVTNILPLQRLASHKQQEKHEYNFGDQLSS-----SSYEHYAKKS--------HFIDHCSKKVFPLLYALFNIVYWSYYL 363
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Nematostella
Match: EDO40889 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S5Y7]) HSP 1 Score: 172.17 bits (435), Expect = 1.439e-49 Identity = 92/288 (31.94%), Postives = 163/288 (56.60%), Query Frame = 1
Query: 238 YKKDERPSEIYQTN---VLVYMKVLAINSVSVTKMEYSTDVYLRQEWTDPRLTWENLEEFRSFNNNIVSPSLKKILWLPDLFFRNGKEGYVHKMTLPNYLMRLRPNGRILYSQKITMRFSCEMNLQTFPMDSQECLMDIGSYGYTLDELKFTWRKEDPILISTGLQISEFNSPHQVSTIDCTNDSSTSTGKYTCLKAKFLLQRQLGSYLVSTFVPSILIVMVSWLNFWINVDSVPARXXXXXXXXXXXXXQATGISSTLPRVSYIKAIDVWVIACIMFVIGALLEYVV 1092
Y+ RP+ YQ + +L+ + V + ++ M++S D++ RQ W DPRL N+ E + P+ +W+PD F + Y+H + + N+ + + P GR+ + + T+ C MNL+ +PMD Q C + I SY Y + L + W+ I + G ++S+F + + G+Y+ LKA F QR++G YL+ ++P + IV V+W++ W++ + PARV+L + TLL + T +++++PRVSY+K+ID++++ FV+G LLEY+V
Sbjct: 11 YESKIRPN--YQGDPVEILIDISVASFGNLQEADMKFSLDMFFRQSWHDPRLR-HNMNETMTLTTGTKHPA--DFVWVPDTVFVDASHAYMHNVMVANHKLDVTPGGRVFWGTRATLIARCHMNLRRYPMDEQTCNLSIISYAYPVRHLLYRWKNSPGIKVLDG-EMSQF---YMTRITTSLRNEIYVAGEYSVLKASFTFQRRVGFYLIQIYIPCMAIVFVAWMSLWVDRRATPARVSLCITTLLTIATIWGNVNASMPRVSYVKSIDIYLMTSFTFVLGTLLEYIV 289
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Nematostella
Match: EDO43147 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RZH2]) HSP 1 Score: 171.785 bits (434), Expect = 1.528e-49 Identity = 96/290 (33.10%), Postives = 166/290 (57.24%), Query Frame = 1
Query: 232 KRYKKDERP-SEIYQTNVLVYMKVLAINSVSVTKMEYSTDVYLRQEWTDPRLTWENLEEFRSFNNNIVSPSLKKILWLPDLFFRNGKEGYVHKMTLPNYLMRLRPNGRILYSQKITMRFSCEMNLQTFPMDSQECLMDIGSYGYTLDELKFTWRKEDPILISTGLQISEFNSPHQVSTIDCTND---SSTSTGKYTCLKAKFLLQRQLGSYLVSTFVPSILIVMVSWLNFWINVDSVPARXXXXXXXXXXXXXQATGISSTLPRVSYIKAIDVWVIACIMFVIGALLEYV 1089
K+Y K RP + V V KV+++ ++ ME+S D++ RQ W +PR T E F ++ K+ W+PD +F N K+ HK+T N + + P+G + YS ++T+ C MNLQ FPMD Q C + I SY YT +++K+ W + G++I N Q ++ + ++ +G ++ L A F L+R+L + ++ P++++V++SW FWI D++PAR++L + T+L L + +++ +P+VSY+KAIDV+V+ F+ +L+EYV
Sbjct: 13 KKYDKKLRPNAGGLPVEVQVEFKVVSLGGINEASMEFSMDIFFRQWWHEPRFTHNYSEPFT------MAEDAGKLFWIPDTYFINAKKSNFHKVTKENARIIIYPSGNVYYSVRLTLTLQCNMNLQLFPMDVQACPLFIESYAYTSEDIKYKWTPRG----TKGIEIIS-NETAQFVLVEARTEQIATAKISGHFSQLVATFSLKRRLEYFAITVVTPAMILVVLSWCCFWIVPDAIPARISLSVTTILSTLLLSGTVNAQMPKVSYMKAIDVFVLGNFAFIFLSLIEYV 291
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Medaka
Match: glra4a (glycine receptor subunit alpha-4-like [Source:NCBI gene;Acc:101156095]) HSP 1 Score: 258.455 bits (659), Expect = 2.922e-80 Identity = 149/422 (35.31%), Postives = 238/422 (56.40%), Query Frame = 1
Query: 175 RKSPMAQQRDLIMERIVDKKRYKKDERPS-EIYQTNVLVYMKVLAINSVSVTKMEYSTDVYLRQEWTDPRLTWENLEEFRSFNNNIVSPSLKKILWLPDLFFRNGKEGYVHKMTLPNYLMRLRPNGRILYSQKITMRFSCEMNLQTFPMDSQECLMDIGSYGYTLDELKFTWRKEDPILISTGLQISEFNSPHQVSTIDCTNDSSTSTGKYTCLKAKFLLQRQLGSYLVSTFVPSILIVMVSWLNFWINVDSVPARXXXXXXXXXXXXXQATGISSTLPRVSYIKAIDVWVIACIMFVIGALLEYVVASVLARKKKS--NGWEKDVREIVRHELARWCSACQRQQFFHLQEQNTLDRNRLEFCSELESLLINHALDAHKGKKTIKTTPTEDSDIDSYSRFLFPACFLLYNCFYWLYYLVLVH 1431
R P D + + + Y RP+ + NV + + + S++ T M+Y +V+LRQ W DPRL + + N+ + PS+ +W PDLFF N K H++T N L+R+ +G +LYS ++T+ SC M+L+ FPMD Q C M + S+GYT+++L F W ++P+ ++ L + +F + CT +TGK+TC++ KF L+RQ+G YL+ ++PS+LIV++SW++FWIN+D+ PARV LG+ T+L M TQ++G ++LP+VSY+KAID+W+ C++FV ALLEY + ++R+ K +K ++ + EL R + + T D LE + + + G+ K ID+ SR +FP FL++N FYWL Y VL H
Sbjct: 36 RAGPQLSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSITETTMDYRLNVFLRQNWNDPRLAYSEYPD----NSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFQDGSVLYSIRLTLILSCPMDLKNFPMDIQTCTMQLESFGYTMNDLIFEWLSDNPVQVADDLTLPQFVLKEEKDLGYCTK--HYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQHKEFIRLRKKQRQQRIEEELVRESRGFYFRGYGLGHCLQTKDGAPLEGATVFSP---PPPMTMYDGEVFSKRFVDRAKRIDTISRAVFPLSFLIFNIFYWLTYKVLRH 448
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Medaka
Match: ENSORLT00000025211.2 (glycine receptor subunit alpha-3 [Source:NCBI gene;Acc:101174559]) HSP 1 Score: 256.144 bits (653), Expect = 2.096e-79 Identity = 145/437 (33.18%), Postives = 245/437 (56.06%), Query Frame = 1
Query: 175 RKSPMAQQRDLIMERIVDKKRYKKDERPS-EIYQTNVLVYMKVLAINSVSVTKMEYSTDVYLRQEWTDPRLTWENLEEFRSFNNNIVSPSLKKILWLPDLFFRNGKEGYVHKMTLPNYLMRLRPNGRILYSQKITMRFSCEMNLQTFPMDSQECLMDIGSYGYTLDELKFTWRKEDPILISTGLQISEFNSPHQVSTIDCTNDSSTSTGKYTCLKAKFLLQRQLGSYLVSTFVPSILIVMVSWLNFWINVDSVPARXXXXXXXXXXXXXQATGISSTLPRVSYIKAIDVWVIACIMFVIGALLEYVVASVLARKKKSNGWEKDVREIVRHELARWCSACQRQQFFHLQEQNTLDRNRLEFCSELESLLINHALDAHKGKKTIKTTPTEDSD-----------------IDSYSRFLFPACFLLYNCFYWLYYLVLVH 1431
R +PM+ D + + + Y RP+ + NV + + + S++ T M+Y +++LRQ+W DPRL + + ++ + PS+ +W PDLFF N K + H++T N L+R+ NG +LYS ++T+ SC M+L+ FPMD Q C+M + S+GYT+++L F W++ P+ ++ GL + +F + CT +TGK+TC++ +F L+RQ+G YL+ ++PS+LIV++SW++FWIN+D+ PARV LG+ T+L M TQ++G ++LP+VSY+KAID+W+ C++FV ALLEY + ++R+ K++ RH+ + +++ + +T S+ +N+A+ T + P ID+ SR FP FL +N FYW+ Y +L H
Sbjct: 29 RHAPMSPS-DFLDKLMGRTSGYDARIRPNFKGPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYAEYPD----DSLDLDPSMLDSIWKPDLFFANEKGAHFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFQWQENGPVQVAEGLTLPQFILKDESDLRYCTK--HYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRTSLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQ------HKELLRFRRHK------SKTKEEVGESKLTSTAVMTSTPSISKDSKASVNNAV--APAANTTQNAPAAGGGGRSTEEMRKLFIDRAKKIDTVSRAGFPLAFLFFNIFYWVLYKILRH 444
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Medaka
Match: glra1 (glycine receptor alpha 1 [Source:NCBI gene;Acc:101173557]) HSP 1 Score: 255.758 bits (652), Expect = 3.189e-79 Identity = 146/417 (35.01%), Postives = 234/417 (56.12%), Query Frame = 1
Query: 226 DKKRYKKDERPSEIYQTNVLVYMKVLAINSVSVTKMEYSTDVYLRQEWTDPRLTWENLEEFRSFNNNIVSPSLKKILWLPDLFFRNGKEGYVHKMTLPNYLMRLRPNGRILYSQKITMRFSCEMNLQTFPMDSQECLMDIGSYGYTLDELKFTWRKEDPILISTGLQISEFNSPHQVSTIDCTNDSSTSTGKYTCLKAKFLLQRQLGSYLVSTFVPSILIVMVSWLNFWINVDSVPARXXXXXXXXXXXXXQATGISSTLPRVSYIKAIDVWVIACIMFVIGALLEYVVASVLARKKKSNGWEKDVREIVRHELARWCSACQRQQFFHLQEQNTLDRNRLEFCSELESLLINHALDAHKGKKTIKTTPTEDSD-----------------IDSYSRFLFPACFLLYNCFYWLYYLVL 1425
D K K + + NV + + + S++ T M+Y +++LRQ+W DPRL + + ++ + PS+ +W PDLFF N K H++T N L+R+ NG +LYS +IT+ +C M+L+ FPMD Q C+M + S+GYT+++L F W ++ + ++ GL + +F + CT +TGK+TC++A+F L+RQ+G YL+ ++PS+LIV++SW++FWIN+D+ PARV LG+ T+L M TQ++G ++LP+VSY+KAID+W+ C++FV ALLEY + +AR+ K E++R R++ H++E T D R F A D K PT + ID+ SR FP FL++N FYW+ Y ++
Sbjct: 51 DPKGSKNEATHKKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPD----DSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLILACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTK--HYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARQHK---------ELLR----------FRRRRRHMKEDETGD-GRFGFPGYGMGPACLQAKDGMAIKGNNNNAPTSAAPEKSIEEMKKLFIGRAKRIDTVSRVAFPLVFLIFNIFYWITYKII 441
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Medaka
Match: glra1 (glycine receptor alpha 1 [Source:NCBI gene;Acc:101173557]) HSP 1 Score: 254.603 bits (649), Expect = 5.447e-79 Identity = 143/400 (35.75%), Postives = 229/400 (57.25%), Query Frame = 1
Query: 277 NVLVYMKVLAINSVSVTKMEYSTDVYLRQEWTDPRLTWENLEEFRSFNNNIVSPSLKKILWLPDLFFRNGKEGYVHKMTLPNYLMRLRPNGRILYSQKITMRFSCEMNLQTFPMDSQECLMDIGSYGYTLDELKFTWRKEDPILISTGLQISEFNSPHQVSTIDCTNDSSTSTGKYTCLKAKFLLQRQLGSYLVSTFVPSILIVMVSWLNFWINVDSVPARXXXXXXXXXXXXXQATGISSTLPRVSYIKAIDVWVIACIMFVIGALLEYVVASVLARKKKSNGWEKDVREIVRHELARWCSACQRQQFFHLQEQNTLDRNRLEFCSELESLLINHALDAHKGKKTIKTTPTEDSD-----------------IDSYSRFLFPACFLLYNCFYWLYYLVL 1425
NV + + + S++ T M+Y +++LRQ+W DPRL + + ++ + PS+ +W PDLFF N K H++T N L+R+ NG +LYS +IT+ +C M+L+ FPMD Q C+M + S+GYT+++L F W ++ + ++ GL + +F + CT +TGK+TC++A+F L+RQ+G YL+ ++PS+LIV++SW++FWIN+D+ PARV LG+ T+L M TQ++G ++LP+VSY+KAID+W+ C++FV ALLEY + +AR+ K E++R R++ H++E T D R F A D K PT + ID+ SR FP FL++N FYW+ Y ++
Sbjct: 55 NVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPD----DSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLILACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTK--HYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARQHK---------ELLR----------FRRRRRHMKEDETGD-GRFGFPGYGMGPACLQAKDGMAIKGNNNNAPTSAAPEKSIEEMKKLFIGRAKRIDTVSRVAFPLVFLIFNIFYWITYKII 428
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Medaka
Match: glra1 (glycine receptor alpha 1 [Source:NCBI gene;Acc:101173557]) HSP 1 Score: 255.373 bits (651), Expect = 5.994e-79 Identity = 146/417 (35.01%), Postives = 234/417 (56.12%), Query Frame = 1
Query: 226 DKKRYKKDERPSEIYQTNVLVYMKVLAINSVSVTKMEYSTDVYLRQEWTDPRLTWENLEEFRSFNNNIVSPSLKKILWLPDLFFRNGKEGYVHKMTLPNYLMRLRPNGRILYSQKITMRFSCEMNLQTFPMDSQECLMDIGSYGYTLDELKFTWRKEDPILISTGLQISEFNSPHQVSTIDCTNDSSTSTGKYTCLKAKFLLQRQLGSYLVSTFVPSILIVMVSWLNFWINVDSVPARXXXXXXXXXXXXXQATGISSTLPRVSYIKAIDVWVIACIMFVIGALLEYVVASVLARKKKSNGWEKDVREIVRHELARWCSACQRQQFFHLQEQNTLDRNRLEFCSELESLLINHALDAHKGKKTIKTTPTEDSD-----------------IDSYSRFLFPACFLLYNCFYWLYYLVL 1425
D K K + + NV + + + S++ T M+Y +++LRQ+W DPRL + + ++ + PS+ +W PDLFF N K H++T N L+R+ NG +LYS +IT+ +C M+L+ FPMD Q C+M + S+GYT+++L F W ++ + ++ GL + +F + CT +TGK+TC++A+F L+RQ+G YL+ ++PS+LIV++SW++FWIN+D+ PARV LG+ T+L M TQ++G ++LP+VSY+KAID+W+ C++FV ALLEY + +AR+ K E++R R++ H++E T D R F A D K PT + ID+ SR FP FL++N FYW+ Y ++
Sbjct: 66 DPKGSKNEATHKKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPD----DSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLILACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTK--HYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARQHK---------ELLR----------FRRRRRHMKEDETGD-GRFGFPGYGMGPACLQAKDGMAIKGNNNNAPTSAAPEKSIEEMKKLFIGRAKRIDTVSRVAFPLVFLIFNIFYWITYKII 456
BLAST of Glycine receptor subunit alpha-3 vs. Planmine SMEST
Match: SMESG000041885.1 (SMESG000041885.1) HSP 1 Score: 857.055 bits (2213), Expect = 0.000e+0 Identity = 425/425 (100.00%), Postives = 425/425 (100.00%), Query Frame = 1
Query: 175 RKSPMAQQRDLIMERIVDKKRYKKDERPSEIYQTNVLVYMKVLAINSVSVTKMEYSTDVYLRQEWTDPRLTWENLEEFRSFNNNIVSPSLKKILWLPDLFFRNGKEGYVHKMTLPNYLMRLRPNGRILYSQKITMRFSCEMNLQTFPMDSQECLMDIGSYGYTLDELKFTWRKEDPILISTGLQISEFNSPHQVSTIDCTNDSSTSTGKYTCLKAKFLLQRQLGSYLVSTFVPSILIVMVSWLNFWINVDSVPARXXXXXXXXXXXXXQATGISSTLPRVSYIKAIDVWVIACIMFVIGALLEYVVASVLARKKKSNGWEKDVREIVRHELARWCSACQRQQFFHLQEQNTLDRNRLEFCSELESLLINHALDAHKGKKTIKTTPTEDSDIDSYSRFLFPACFLLYNCFYWLYYLVLVHYAQNIS 1449
RKSPMAQQRDLIMERIVDKKRYKKDERPSEIYQTNVLVYMKVLAINSVSVTKMEYSTDVYLRQEWTDPRLTWENLEEFRSFNNNIVSPSLKKILWLPDLFFRNGKEGYVHKMTLPNYLMRLRPNGRILYSQKITMRFSCEMNLQTFPMDSQECLMDIGSYGYTLDELKFTWRKEDPILISTGLQISEFNSPHQVSTIDCTNDSSTSTGKYTCLKAKFLLQRQLGSYLVSTFVPSILIVMVSWLNFWINVDSVPARVTLGLVTLLGMLTQATGISSTLPRVSYIKAIDVWVIACIMFVIGALLEYVVASVLARKKKSNGWEKDVREIVRHELARWCSACQRQQFFHLQEQNTLDRNRLEFCSELESLLINHALDAHKGKKTIKTTPTEDSDIDSYSRFLFPACFLLYNCFYWLYYLVLVHYAQNIS
Sbjct: 24 RKSPMAQQRDLIMERIVDKKRYKKDERPSEIYQTNVLVYMKVLAINSVSVTKMEYSTDVYLRQEWTDPRLTWENLEEFRSFNNNIVSPSLKKILWLPDLFFRNGKEGYVHKMTLPNYLMRLRPNGRILYSQKITMRFSCEMNLQTFPMDSQECLMDIGSYGYTLDELKFTWRKEDPILISTGLQISEFNSPHQVSTIDCTNDSSTSTGKYTCLKAKFLLQRQLGSYLVSTFVPSILIVMVSWLNFWINVDSVPARVTLGLVTLLGMLTQATGISSTLPRVSYIKAIDVWVIACIMFVIGALLEYVVASVLARKKKSNGWEKDVREIVRHELARWCSACQRQQFFHLQEQNTLDRNRLEFCSELESLLINHALDAHKGKKTIKTTPTEDSDIDSYSRFLFPACFLLYNCFYWLYYLVLVHYAQNIS 448
BLAST of Glycine receptor subunit alpha-3 vs. Planmine SMEST
Match: SMESG000077704.1 (SMESG000077704.1) HSP 1 Score: 589.726 bits (1519), Expect = 0.000e+0 Identity = 299/419 (71.36%), Postives = 346/419 (82.58%), Query Frame = 1
Query: 181 SPMAQQRDLIMERIVDKKRYKKDERPSEIYQTNVLVYMKVLAINSVSVTKMEYSTDVYLRQEWTDPRLTWENLEEFRSFNNNIVSPSLKKILWLPDLFFRNGKEGYVHKMTLPNYLMRLRPNGRILYSQKITMRFSCEMNLQTFPMDSQECLMDIGSYGYTLDELKFTWRKEDPILISTGLQISEFNSPHQVSTIDCTNDSSTSTGKYTCLKAKFLLQRQLGSYLVSTFVPSILIVMVSWLNFWINVDSVPARXXXXXXXXXXXXXQATGISSTLPRVSYIKAIDVWVIACIMFVIGALLEYVVASVLARKKKSNGWEKDVREIVRHELARWCSACQRQQFFHLQEQNTLDRNRLEFCSELESLLINHALDAHKGKKTIKTTPTEDSDIDSYSRFLFPACFLLYNCFYWLYYLVLVHYA 1437
S A QR LI I K Y K++RP E QT V VYMK+LAINSVSVT+MEYSTDVYLRQEW D RL W NL++F+S+N NIVSPSLKK+LWLPDLFFRNGKEGYVHKMTLPNYLMRL PNG ILYSQKITMRFSC+M+L+TFPMD+Q C MDIGSYGYTLDEL+F WR D I I+TG+QISEFNSP + +T DCT SSTSTG+Y+CLKA+F+LQRQLGSY+VSTFVPSILIVMVSWLNFWI+VDSVPARV LGLVTLLGMLTQA GISSTLPRVSYIKAID+WVI CI+FVI ALLEY VA+ + + SN E +V+ IV+ EL WC+A R Q H+Q N+LDR+RL+FC +LE+LLI A+D+H KK IK P E+S +D YSRFLFPA FL YNCFYW+Y+LVLV+Y+
Sbjct: 26 SEKADQRSLIRAEIFSK--YLKEDRPKEEEQTEVTVYMKILAINSVSVTQMEYSTDVYLRQEWVDSRLAWNNLDKFKSYNANIVSPSLKKVLWLPDLFFRNGKEGYVHKMTLPNYLMRLSPNGLILYSQKITMRFSCQMDLKTFPMDTQICEMDIGSYGYTLDELRFNWRVNDSISIATGMQISEFNSPGKFTTRDCTKLSSTSTGQYSCLKAEFVLQRQLGSYIVSTFVPSILIVMVSWLNFWIHVDSVPARVMLGLVTLLGMLTQAIGISSTLPRVSYIKAIDIWVIWCIIFVICALLEYAVANSVVARNYSNNMENEVKLIVQRELMNWCTAFDRLQISHMQVHNSLDRDRLQFCHDLENLLIEKAIDSH--KKVIKVRPPENSIVDVYSRFLFPALFLFYNCFYWVYFLVLVNYS 440
BLAST of Glycine receptor subunit alpha-3 vs. Planmine SMEST
Match: SMESG000037124.1 (SMESG000037124.1) HSP 1 Score: 524.242 bits (1349), Expect = 0.000e+0 Identity = 267/441 (60.54%), Postives = 333/441 (75.51%), Query Frame = 1
Query: 187 MAQQRDLIMERIVDKKRYKKDERPSEIYQTNVLVYMKVLAINSVSVTKMEYSTDVYLRQEWTDPRLTWENLEEFRSFNNNIVSPSLKKILWLPDLFFRNGKEGYVHKMTLPNYLMRLRPNGRILYSQKITMRFSCEMNLQTFPMDSQECLMDIGSYGYTLDELKFTWRKEDPILISTGLQISEFNSPHQVSTIDCTNDSSTSTGKYTCLKAKFLLQRQLGSYLVSTFVPSILIVMVSWLNFWINVDSVPARXXXXXXXXXXXXXQATGISSTLPRVSYIKAIDVWVIACIMFVIGALLEYVVASVLARKKKSNGWEKDVREIVRHELARWCS-ACQRQQ-----------------FFHLQEQNTLDRNRLEFCSELESLLINHALDAHKGKKTIKTT--------PTE-DSDIDSYSRFLFPACFLLYNCFYWLYYLVLV 1428
M R+ I I K YK +ERPSE QT V VYMKVLAINSV V KMEYSTDVYLRQEW D RL W+++E+FRS+NNN+VSP K+ +WLPDLFFRNGK+GYVH MT PNYL+RL+PNG +LYSQKITM+FSC+M+LQTFPMD+QEC MDIGSYGYTLD+LKF WR +P+++ +QI EFN P V TIDC+ SSTSTG YTC+KA F LQRQLGSYL ST++P++LIVMVSWLNFW+++D+VPAR+TLGL+TLLG+LTQATG+S+ LPRVSYIKAIDVW+IACI+FVIGAL+E+ +AS+++RK KS W++DV+ IV EL +W A ++QQ F +L + N+ D + EF +LE L L+A +K K+ P + DS+ID YS+FLFPA F+LYNCFYWLYYL+LV
Sbjct: 10 MNSDREQIQNHIF--KGYKSNERPSENKQTIVTVYMKVLAINSVDVIKMEYSTDVYLRQEWIDERLAWDHIEKFRSYNNNLVSPLFKEKIWLPDLFFRNGKDGYVHSMTTPNYLLRLQPNGEVLYSQKITMKFSCQMDLQTFPMDTQECNMDIGSYGYTLDQLKFRWRSWEPMILPPVMQIPEFNQPTNVKTIDCSELSSTSTGDYTCIKATFFLQRQLGSYLASTYIPNVLIVMVSWLNFWVSIDAVPARITLGLLTLLGILTQATGMSANLPRVSYIKAIDVWIIACILFVIGALIEFAIASMISRKSKSELWQRDVQNIVHQELFKWSKMALKKQQSINFLQMHLMGTPKTNSFTNLAQMNSTDNSANEFYHKLEVFLTAQLLEASPNEKLRKSISKPQVSEPPVQIDSEIDGYSQFLFPAFFMLYNCFYWLYYLILV 448
BLAST of Glycine receptor subunit alpha-3 vs. Planmine SMEST
Match: SMESG000032691.1 (SMESG000032691.1) HSP 1 Score: 523.857 bits (1348), Expect = 0.000e+0 Identity = 261/415 (62.89%), Postives = 327/415 (78.80%), Query Frame = 1
Query: 214 ERIVDK--KRYKKDERPSEIYQTNVLVYMKVLAINSVSVTKMEYSTDVYLRQEWTDPRLTWENLEEFRSFNNNIVSPSLKKILWLPDLFFRNGKEGYVHKMTLPNYLMRLRPNGRILYSQKITMRFSCEMNLQTFPMDSQECLMDIGSYGYTLDELKFTWRKEDPILISTGLQISEFNSPHQVSTIDCTNDSSTSTGKYTCLKAKFLLQRQLGSYLVSTFVPSILIVMVSWLNFWINVDSVPARXXXXXXXXXXXXXQATGISSTLPRVSYIKAIDVWVIACIMFVIGALLEYVVASVLARKKKSNGWEKDVREIVRHELARWCSACQRQQFFHLQEQNTLDRNRLEFCSELESLLINHAL--------DAHKGKKTIKTTPTEDSDIDSYSRFLFPACFLLYNCFYWLYYLVLV 1428
ERI+DK + Y +ERP E QT V+V+MKVLAINSV+V+ MEYSTD+YLRQ W D RL W+NL EF+ FN+++VSPSLK LWLPDLFFRNGKEGYVH MT PNYLMRL PNG +LYSQKITMRFSC+M+LQT+PMD+Q C M+IGSYGYTLD+LKF W + +P+ + +QI EFN+P +V T DCTN S+T TG Y+CLKA F+L+RQLGSYLVSTF+P+ LIV+VSWLNFW++V++VPAR+TLGL+TLLG+LTQA+GIS LPRVSYIKAIDVW+IACI+FVIGALLE+ VAS +A++KK W+ +VR+IVR EL+RW A RQ+ H+Q L+RN LEFC EL+ LL AH+ K+ + E+S ID YSR+LFP+CF+ YN YW+YYL++V
Sbjct: 32 ERIMDKILQNYSLNERPIESNQTRVMVFMKVLAINSVNVSNMEYSTDLYLRQLWVDARLRWDNLNEFKHFNSSLVSPSLKDRLWLPDLFFRNGKEGYVHIMTKPNYLMRLFPNGEVLYSQKITMRFSCQMDLQTYPMDTQSCEMNIGSYGYTLDQLKFYWSQTNPMELGNNVQIPEFNAPTKVETNDCTNSSTTETGFYSCLKALFILRRQLGSYLVSTFIPNTLIVIVSWLNFWVSVEAVPARITLGLLTLLGILTQASGISGNLPRVSYIKAIDVWLIACIVFVIGALLEFAVASTVAQQKKLYQWKSEVRDIVRQELSRWNLAINRQKTHHMQTSQILNRNELEFCEELDILLTAQQYANNYHSQESAHQIKRQKILSEIEESKIDVYSRYLFPSCFIFYNFCYWIYYLIIV 446
BLAST of Glycine receptor subunit alpha-3 vs. Planmine SMEST
Match: SMESG000061905.1 (SMESG000061905.1) HSP 1 Score: 500.36 bits (1287), Expect = 1.358e-174 Identity = 264/409 (64.55%), Postives = 328/409 (80.20%), Query Frame = 1
Query: 232 KRYKKDERPSEIYQTNVLVYMKVLAINSVSVTKMEYSTDVYLRQEWTDPRLTWENLEEFRSFNNNIVSPSLKKILWLPDLFFRNGKEGYVHKMTLPNYLMRLRPNGRILYSQKITMRFSCEMNLQTFPMDSQECLMDIGSYGYTLDELKFTWRKEDPILISTGLQISEFNSPHQVSTIDCTNDSSTSTGKYTCLKAKFLLQRQLGSYLVSTFVPSILIVMVSWLNFWINVDSVPARXXXXXXXXXXXXXQATGISSTLPRVSYIKAIDVWVIACIMFVIGALLEYVVASVLARKKKSNGWEKDVREIVRHELARWCSACQRQQFFHLQEQNTLDRNRLEF---CSELESLLINHALDAHKGK---KTIKTTPTE--DSDIDSYSRFLFPACFLLYNCFYWLYYLVLVHY 1434
+ Y ERPSE+ QT V+VYM+VLAINSV V KMEYSTDV LRQEW D RLTW S+N +I SP+LK+ +WLPDLFFRNGK+GYVH MTLPNYLMRL NG ILYSQKITMRFSC+MNL TFPMDSQEC+MDIGSYGYTLD+LKF WR+++PI+I++ +QI EFN T DC+ ++ TSTG YTCLKA F L+RQLGSYL ST++P++LIVMVSWLNFW++V+++PAR+TLGL+TLLG+LTQATG+S++LPRVSYIKAID+W+IACI+FVIGAL+E+ +AS++AR++KS W+K VREIVR ELARWC+ CQ+QQ +Q + +DR + E +LE LL + K K K ++ P + DS+ID YSRFLFPACF+LYNCFYWLYYLVLVH+
Sbjct: 58 ENYNLHERPSEVKQTEVVVYMRVLAINSVDVLKMEYSTDVLLRQEWLDDRLTWHRHPRLASYNKSISSPALKEKVWLPDLFFRNGKKGYVHSMTLPNYLMRLNSNGMILYSQKITMRFSCQMNLSTFPMDSQECIMDIGSYGYTLDQLKFLWREKEPIIIASNIQIPEFNPSTDPYTFDCSKEAGTSTGNYTCLKASFHLRRQLGSYLASTYIPNVLIVMVSWLNFWVSVEAIPARITLGLLTLLGILTQATGMSNSLPRVSYIKAIDIWIIACIIFVIGALIEFAMASMIARRRKSEDWQKQVREIVRQELARWCAVCQQQQLVQIQNSSLIDRTQFETPIGTEDLEILLCPDTVQKWKKKPVQKVNRSKPQKSVDSEIDCYSRFLFPACFVLYNCFYWLYYLVLVHH 466 The following BLAST results are available for this feature:
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Glycine receptor subunit alpha-3 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Glycine receptor subunit alpha-3 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Glycine receptor subunit alpha-3 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30018078 ID=SMED30018078|Name=Glycine receptor subunit alpha-3|organism=Schmidtea mediterranea sexual|type=transcript|length=1556bpback to top protein sequence of SMED30018078-orf-1 >SMED30018078-orf-1 ID=SMED30018078-orf-1|Name=SMED30018078-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=449bp MNPIFFIVLVLLLNSLRLLSIPRRKSPMAQQRDLIMERIVDKKRYKKDERback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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