HTH CENPB-type domain-containing protein

Overview
NameHTH CENPB-type domain-containing protein
Smed IDSMED30017976
Length (bp)934
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of HTH CENPB-type domain-containing protein (SMED30017976) t-SNE clustered cells

Violin plots show distribution of expression levels for HTH CENPB-type domain-containing protein (SMED30017976) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of HTH CENPB-type domain-containing protein (SMED30017976) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for HTH CENPB-type domain-containing protein (SMED30017976) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30017976

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 5

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
pharynxSMED30017976h1SMcG0018298 dd_Smed_v4_12660_2_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
nervous systemSMED30017976h1SMcG0018298 dd_Smed_v4_12660_2_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30017976h1SMcG0018298 dd_Smed_v4_12660_2_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30017976h1SMcG0018298 dd_Smed_v4_12660_2_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30017976h1SMcG0018298 dd_Smed_v4_12660_2_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of HTH CENPB-type domain-containing protein vs. Ensembl Human
Match: TIGD1 (tigger transposable element derived 1 [Source:HGNC Symbol;Acc:HGNC:14523])

HSP 1 Score: 206.838 bits (525), Expect = 3.623e-67
Identity = 101/184 (54.89%), Postives = 134/184 (72.83%), Query Frame = 1 
Query:   19 EFLEENNYTKEQIFNVDETGLYWKRMPERTYIHKEEKSMPGFKAFKDRITVLLGGNIVG-YKLKPFVVHRSKNPRAFKGVKRNMLPVNYNSNKSAWMTQLLFEDWFMNVFATEVKEYCNQHKIPFRILLLLDNAXXXXXXXXXXXXNIQIMYLPPNTTSILQPMDQGAIATFKAHYLINYIHSS 567
            + ++E  YTK+QIFNVDET  YWK+MP RT+I +EEKS+PGFKA KDR+T+LLG N  G +KLKP +++ S+NPRA K   ++ LPV Y  N  A MT  LF  WF   F   V+ YC++ KIPF+ILLL+DNAP HP  L +++  I ++++P NTTSILQPMDQG I+TFK++YL N  H +
Sbjct:  171 KIIDEGGYTKQQIFNVDETAFYWKKMPSRTFIAREEKSVPGFKASKDRLTLLLGANAAGDFKLKPMLIYHSENPRALKNYTKSTLPVLYKWNSKARMTAHLFTAWFTEYFKPTVETYCSEKKIPFKILLLIDNAPSHPRALMEIYEEINVIFMPANTTSILQPMDQGVISTFKSYYLRNTFHKA 354

HSP 2 Score: 68.5514 bits (166), Expect = 3.623e-67
Identity = 41/124 (33.06%), Postives = 68/124 (54.84%), Query Frame = 2 
Query:  554 TFTQAIMAIEEGIT-------LKEFWSKFNILQGIINLASGWKEVKASCMSGIWKKLTKI----FEESRSSSIEKEVDVEEITDQIVDLGWQLNLEVDSEDINQLIAHQLDDLANEDLLEFEAQ 892
            TF +A+ A++  ++       LK FW  F IL  I N+   W+EVK S ++G+WKKL       +E  ++S       VEE++  +V++  +L LEV+ ED+ +L+      L +E+L   +AQ
Sbjct:  350 TFHKALAAMDSDVSDGSGQSKLKTFWKGFTILDAIKNIRDSWEEVKLSTLTGVWKKLIPTLIDDYEGFKTS-------VEEVSADVVEIAKELELEVEPEDVTELLQSHDKTLTDEELFLMDAQ 466
[Close]
BLAST of HTH CENPB-type domain-containing protein vs. Ensembl Human
Match: JRKL (JRK like [Source:HGNC Symbol;Acc:HGNC:6200])

HSP 1 Score: 149.058 bits (375), Expect = 2.268e-42
Identity = 78/184 (42.39%), Postives = 110/184 (59.78%), Query Frame = 1 
Query:    1 FVVKFNEFLEENNYTKEQIFNVDETGLYWKRMPERTYIHKEEKSMPGFKAFKDRITVLLGGNIVG-YKLKPFVVHRSKNPRAFKGVKRNMLPVNYNSNKSAWMTQLLFEDWFMNVFATEVKEYCNQHKIPFRILLLLDNAXXXXXXXXXXXXNIQIM--YLPPNTTSILQPMDQGAIATFKAHY 543
            F   F +F+E  N   EQI+N DETGL+WK +P R  + K + ++PG K+ ++R+T++   N  G +KLK  VV ++K PR+FK      LPV+Y S K AWM   +F  WF  +F  +V+EY     +  + +LLLDN+P HP        + QI   YLPPN  S++QP DQG IAT K +Y
Sbjct:  155 FCNNFRDFIERENLQPEQIYNADETGLFWKCLPSRISVIKGKCTVPGHKSIEERVTIMCCANATGLHKLKLCVVGKAKKPRSFKSTDTLNLPVSYFSQKGAWMDLSIFRQWFDKIFVPQVREYLRSKGLQEKAVLLLDNSPTHPNENVLRSDDGQIFAKYLPPNVASLIQPSDQGVIATMKRNY 338

HSP 2 Score: 43.5134 bits (101), Expect = 2.268e-42
Identity = 24/64 (37.50%), Postives = 34/64 (53.12%), Query Frame = 2 
Query:  578 IEEGITLKEFWSKFNILQGIINLASGWKEVKASCMSGIWKKLTKIFEESRSSSIEKEVDVEEIT 769
            +EEG  LK FW K  +L  +  +A  W  VK   +S  WKK+  + EE  S     + DVE+I+
Sbjct:  347 LEEGNDLKSFWKKLTLLDALYEIAMAWNLVKPVTISRAWKKILPMVEEKESL----DFDVEDIS 406
[Close]
BLAST of HTH CENPB-type domain-containing protein vs. Ensembl Human
Match: TIGD2 (tigger transposable element derived 2 [Source:HGNC Symbol;Acc:HGNC:18333])

HSP 1 Score: 140.198 bits (352), Expect = 2.912e-37
Identity = 72/184 (39.13%), Postives = 106/184 (57.61%), Query Frame = 1 
Query:    1 FVVKFNEFLEENNYTKEQIFNVDETGLYWKRMPERTYIHKEEKSMPGFKAFKDRITVLLGGNIVG-YKLKPFVVHRSKNPRAFKGVKRNMLPVNYNSNKSAWMTQLLFEDWFMNVFATEVKEYCNQHKIPFRILLLLD--NAXXXXXXXXXXXXNIQIMYLPPNTTSILQPMDQGAIATFKAHY 543
            F   F EF+E+ N   EQI+  D+TGL+WK +P RT   + ++S  G ++ ++RI ++   N  G +KL   VV ++K PRAFKG   + LPV Y S K AW+ Q +F  WF   F  +V+++     +  + +LLLD   A  +   L      I + YLPPN TS++QPM QG +AT K +Y
Sbjct:  155 FCGSFQEFVEKENLQPEQIYGADQTGLFWKCLPSRTLTLETDQSTSGCRSSRERIIIMCCANATGLHKLNLCVVGKAKKPRAFKGTDLSNLPVTYYSQKGAWIEQSVFRQWFEKYFVPQVQKHLKSKGLLEKAVLLLDFPPARPNEEMLSSDDGRIIVKYLPPNVTSLIQPMSQGVLATVKRYY 338

HSP 2 Score: 35.039 bits (79), Expect = 2.912e-37
Identity = 18/55 (32.73%), Postives = 29/55 (52.73%), Query Frame = 2 
Query:  578 IEEGITLKEFWSKFNILQGIINLASGWKEVKASCMSGIWKKLTKIFEESRSSSIE 742
            ++EG   K FW    +L  I  ++  W  VK+S ++  WKKL    EE+   +I+
Sbjct:  347 MDEGNDPKIFWKNLTVLDAIYEVSRAWNMVKSSTITKAWKKLFPGNEENSGMNID 401
[Close]
BLAST of HTH CENPB-type domain-containing protein vs. Ensembl Human
Match: TIGD2 (tigger transposable element derived 2 [Source:HGNC Symbol;Acc:HGNC:18333])

HSP 1 Score: 140.198 bits (352), Expect = 2.912e-37
Identity = 72/184 (39.13%), Postives = 106/184 (57.61%), Query Frame = 1 
Query:    1 FVVKFNEFLEENNYTKEQIFNVDETGLYWKRMPERTYIHKEEKSMPGFKAFKDRITVLLGGNIVG-YKLKPFVVHRSKNPRAFKGVKRNMLPVNYNSNKSAWMTQLLFEDWFMNVFATEVKEYCNQHKIPFRILLLLD--NAXXXXXXXXXXXXNIQIMYLPPNTTSILQPMDQGAIATFKAHY 543
            F   F EF+E+ N   EQI+  D+TGL+WK +P RT   + ++S  G ++ ++RI ++   N  G +KL   VV ++K PRAFKG   + LPV Y S K AW+ Q +F  WF   F  +V+++     +  + +LLLD   A  +   L      I + YLPPN TS++QPM QG +AT K +Y
Sbjct:  155 FCGSFQEFVEKENLQPEQIYGADQTGLFWKCLPSRTLTLETDQSTSGCRSSRERIIIMCCANATGLHKLNLCVVGKAKKPRAFKGTDLSNLPVTYYSQKGAWIEQSVFRQWFEKYFVPQVQKHLKSKGLLEKAVLLLDFPPARPNEEMLSSDDGRIIVKYLPPNVTSLIQPMSQGVLATVKRYY 338

HSP 2 Score: 35.039 bits (79), Expect = 2.912e-37
Identity = 18/55 (32.73%), Postives = 29/55 (52.73%), Query Frame = 2 
Query:  578 IEEGITLKEFWSKFNILQGIINLASGWKEVKASCMSGIWKKLTKIFEESRSSSIE 742
            ++EG   K FW    +L  I  ++  W  VK+S ++  WKKL    EE+   +I+
Sbjct:  347 MDEGNDPKIFWKNLTVLDAIYEVSRAWNMVKSSTITKAWKKLFPGNEENSGMNID 401
[Close]
BLAST of HTH CENPB-type domain-containing protein vs. Ensembl Human
Match: JRK (Jrk helix-turn-helix protein [Source:HGNC Symbol;Acc:HGNC:6199])

HSP 1 Score: 126.716 bits (317), Expect = 3.574e-32
Identity = 66/189 (34.92%), Postives = 109/189 (57.67%), Query Frame = 1 
Query:    1 FVVKFNEFLEENNYTKEQIFNVDETGLYWKRMPERTYIHKEEKSMPGFKAFKDRITVLLGGNIVG-YKLKPFVVHRSKNPRAFKGVKRNMLPVNYNSNKSAWMTQLLFEDWFMNVFATEVKEYCNQHKIP--FRILLLLDNAXXXXXXXXXXXXNIQIMYLPPNTTSILQPMDQGAIATFKAHYLINYI 558
            F   F     E+  + EQ++N DETGL+W+ +P  T    E  ++PG K  KDR+TVL+  N  G ++LKP  + +   PRAFKG++   LPV Y +  +AW+ + +F DWF ++F   V+E+     +P   + +LLLD++  HP     +  N+  ++LP +  S++QPM+QG     +  ++ N+I
Sbjct:  165 FCAFFRSLAAEHGLSAEQVYNADETGLFWRCLPNPT---PEGGAVPGPKQGKDRLTVLMCANATGSHRLKPLAIGKCSGPRAFKGIQH--LPVAYKAQGNAWVDKEIFSDWFHHIFVPSVREHFRTIGLPEDSKAVLLLDSSRAHPQEAELVSSNVFTIFLPASVASLVQPMEQG----IRRDFMRNFI 344
[Close]
BLAST of HTH CENPB-type domain-containing protein vs. Ensembl Xenopus
Match: kif6 (kinesin family member 6 [Source:Xenbase;Acc:XB-GENE-1014042])

HSP 1 Score: 128.257 bits (321), Expect = 1.931e-32
Identity = 67/209 (32.06%), Postives = 119/209 (56.94%), Query Frame = 1 
Query:    1 FVVKFNEFLEENNYTKEQIFNVDETGLYWKRMPERTYIHKEEKSMPGFKAFKDRITVLLGGNIVG-YKLKPFVVHRSKNPRAFKGVKRNMLPVNYNSNKSAWMTQLLFEDWFMNVFATEVKEYCNQHKIP--FRILLLLDNAXXXXXXXXXXXXNIQIMYLPPNTTSILQPMDQGAIATFKAHYLINYIHSSNYGY*RGDYFKRILVEV 618
            FV K N+ + + + + EQ++N  +  L+W+ +P++     ++    G +  K+R+TVL   N  G +K +  V+ +S+NPRAFKGV+  + PV Y +NK A +T+ +F+DWF N F  E + +C    +    +++L+LD+ P HP     +  N+  + LPP+ TS +QP+DQG +  FK++Y             + ++ +R+L E 
Sbjct:  332 FVKKLNKLVSDEHLSAEQVYNAAKASLFWRHLPQKLVATAQKPPSSGLEDPKERLTVLACSNAAGTHKARLLVIGKSRNPRAFKGVR--VFPVTYTANKQAGITREIFQDWFENHFVPEARAHCMSVGLSQDAKVMLILDHCPTHPSAEFLVKDNVFAVCLPPDCTSFIQPLDQGILRLFKSNY-------------KSEFLQRMLTEC 525
[Close]
BLAST of HTH CENPB-type domain-containing protein vs. Ensembl Xenopus
Match: apmapl (adipocyte plasma membrane associated protein LIKE [Source:Xenbase;Acc:XB-GENE-5754317])

HSP 1 Score: 80.4925 bits (197), Expect = 2.223e-16
Identity = 45/135 (33.33%), Postives = 76/135 (56.30%), Query Frame = 1 
Query:  148 AFKDRITVLLGGNIVG-YKLKPFVVHRSKNPRAFKGVKRNMLPVNYNSNKSAWMTQLLFEDWFMNVFATEVKEYCNQHKIPFRILLLLDNAXXX--XXXXXXXXXNIQIMYLPPNTTSILQPMDQGAIATFKAHY 543
             + D +TVLL  N+ G +KLKP VV + ++P + +   ++  P  Y+ +++AW+TQ L  +WF+  F   VK Y  +  +  + +LL++  PG      L     NI++++L   T S +  MDQG I++FK  Y
Sbjct:  171 GYGDEVTVLLAANLTGSHKLKPLVVGKLRDPPSLRHHNQDKFPAVYHYSRNAWVTQELLREWFLEEFVPAVKRYLKRCCLQQKAVLLVNQCPGKPPEEDLQTADGNIRVLFLSKTTRSKIPSMDQGVISSFKQLY 305
[Close]
BLAST of HTH CENPB-type domain-containing protein vs. Ensembl Xenopus
Match: ENSXETT00000046714.1 (pep primary_assembly:Xenopus_tropicalis_v9.1:KV460367.1:582927:585046:-1 gene:ENSXETG00000018570.1 transcript:ENSXETT00000046714.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 77.7962 bits (190), Expect = 1.655e-15
Identity = 53/127 (41.73%), Postives = 70/127 (55.12%), Query Frame = 1 
Query:   40 YTKEQIFNVDETGLYWKRMPERTYIHKEEKSMPGFKAFKDRITVLLGGNIVGY-KLKPFVVHRSKNPRAFKGVKRNMLPVNYNSNKSAWMTQLLFEDWFMNVFATEVKEYCNQHKIPFRILLLLDNA 417
            Y  + IFN DETGL++  +P +T+  + E    G K  K R+TVL   N  G  KLKP V+ +S  PR FK V  N LP NY +N  AWMT  LFE+  M++    ++    +HK    ILL LD  
Sbjct:  166 YELKNIFNTDETGLFFNVLPGKTFCFRGEDCHGG-KLSKLRLTVLFTTNADGSEKLKPLVIGKSVKPRCFKNV--NTLPTNYTANTKAWMTTKLFEEQ-MHLLDNRMR--LQKHK----ILLFLDRC 282
[Close]
BLAST of HTH CENPB-type domain-containing protein vs. Ensembl Mouse
Match: Jrkl (Jrk-like [Source:MGI Symbol;Acc:MGI:1924782])

HSP 1 Score: 146.362 bits (368), Expect = 1.865e-40
Identity = 78/190 (41.05%), Postives = 111/190 (58.42%), Query Frame = 1 
Query:    1 FVVKFNEFLEENNYTKEQIFNVDETGLYWKRMPERTYIHKEEKSMPGFKAFKDRITVLLGGNIVG-YKLKPFVVHRSKNPRAFKGVKRNMLPVNYNSNKSAWMTQLLFEDWFMNVFATEVKEYCNQHKIPFRILLLLDNAXXXXXXXXXXXXNIQIM--YLPPNTTSILQPMDQGAIATFKAHYLINYIH 561
            F   F +F+E+ N   EQI+N DETGL+WK +P RT + K + ++PG    ++RITV+   N  G +KLK  VV +++ PR+FK      LPV+Y S K AWM   +F  WF  +F  +V+EY     +  + +LLLDN+P HP        + QI   YLPPN  S++QP+ QG IA  K +Y    +H
Sbjct:  155 FCNNFRDFIEQENLQPEQIYNADETGLFWKCLPSRTTVIKGKCTVPGHNLGEERITVMCCTNATGLHKLKLCVVGKARKPRSFKSTDTLNLPVSYFSQKGAWMDLSIFRQWFDKIFVPQVREYLRSKGLQEKAVLLLDNSPTHPNENVLRSDDGQIFAKYLPPNVASLIQPLGQGVIAAMKRNYRAGLLH 344

HSP 2 Score: 39.2762 bits (90), Expect = 1.865e-40
Identity = 18/48 (37.50%), Postives = 25/48 (52.08%), Query Frame = 2 
Query:  578 IEEGITLKEFWSKFNILQGIINLASGWKEVKASCMSGIWKKLTKIFEE 721
            +EEG  LK FW K  +L  +  +A  W  VK   +S  WK++    EE
Sbjct:  347 LEEGNDLKSFWKKLTLLDALYEIAMAWNLVKPVTISRAWKQILPAIEE 394
[Close]
BLAST of HTH CENPB-type domain-containing protein vs. Ensembl Mouse
Match: Tigd2 (tigger transposable element derived 2 [Source:MGI Symbol;Acc:MGI:1915390])

HSP 1 Score: 133.265 bits (334), Expect = 5.850e-36
Identity = 70/190 (36.84%), Postives = 102/190 (53.68%), Query Frame = 1 
Query:    1 FVVKFNEFLEENNYTKEQIFNVDETGLYWKRMPERTYIHKEEKSMPGFKAFKDRITVLLGGNIVG-YKLKPFVVHRSKNPRAFKGVKRNMLPVNYNSNKSAWMTQLLFEDWFMNVFATEVKEYCNQHKIPFRILLLLD--NAXXXXXXXXXXXXNIQIMYLPPNTTSILQPMDQGAIATFKAHYLINYIH 561
            F   F EF+E  N   EQI+  D+TGL+WK +P RT     ++S   ++  ++RI ++   N  G +KL   VV ++K PRAFKG   + LPV Y S KSAW+   + + WF   F  +V+++     +  + +LLLD   A      L      I + YLPPN TS++QPM QG + T K +Y    I 
Sbjct:  155 FCGNFQEFVERENLLPEQIYGADQTGLFWKCLPTRTLAFDTDQSTCEYRTSRERIIIMCCANATGSHKLNLCVVGKAKRPRAFKGTDLSNLPVTYFSQKSAWIEPSVLKQWFEKCFVPQVQKHLKSKGLREKAVLLLDFPAAHPAEELLSSDDGRIIVKYLPPNVTSLIQPMSQGVLTTVKRYYRAGLIQ 344

HSP 2 Score: 37.3502 bits (85), Expect = 5.850e-36
Identity = 17/55 (30.91%), Postives = 30/55 (54.55%), Query Frame = 2 
Query:  578 IEEGITLKEFWSKFNILQGIINLASGWKEVKASCMSGIWKKLTKIFEESRSSSIE 742
            ++EG   K FW    +L  I   +  W +++++ ++  WKKL    EE+ S SI+
Sbjct:  347 MDEGNDPKTFWKNLTVLDAIYEASRAWNQIRSNTITRAWKKLFPGNEENPSVSID 401
[Close]
BLAST of HTH CENPB-type domain-containing protein vs. Ensembl Mouse
Match: Jrk (jerky [Source:MGI Symbol;Acc:MGI:106214])

HSP 1 Score: 120.168 bits (300), Expect = 1.780e-30
Identity = 57/171 (33.33%), Postives = 100/171 (58.48%), Query Frame = 1 
Query:   13 FNEFLEENNYTKEQIFNVDETGLYWKRMPERTYIHKEEKSMPGFKAFKDRITVLLGGNIVG-YKLKPFVVHRSKNPRAFKGVKRNMLPVNYNSNKSAWMTQLLFEDWFMNVFATEVKEYCNQHKIP--FRILLLLDNAXXXXXXXXXXXXNIQIMYLPPNTTSILQPMDQG 516
            F     E+  + EQ+++ DETGL W+ +P       ++ ++P FK  KDR+TVL+  N  G +++KP  + +   PRAF+G++   LP+ Y +  +AW+ + +F DWF ++F   V+E+     +P   + +LLLD++  H      +  N+  ++LP + TS+LQP +QG
Sbjct:  169 FRSLAAEHGLSPEQVYSADETGLVWRCLPNSA---PDDGTVPHFKQGKDRLTVLMCANATGSHRIKPLAIGKGGGPRAFRGIQH--LPIAYKAQGNAWVDKEIFSDWFHHIFVPSVREHFRTIGLPEDSKAILLLDHSRAHSQESELVSENVFTIFLPSSVTSLLQPTEQG 334

HSP 2 Score: 31.9574 bits (71), Expect = 1.780e-30
Identity = 12/42 (28.57%), Postives = 20/42 (47.62%), Query Frame = 2 
Query:  578 IEEGITLKEFWSKFNILQGIINLASGWKEVKASCMSGIWKKL 703
            I   +  + F ++ NI   I+N+A  W  V +      W+KL
Sbjct:  344 INPPVAFQGFPTRHNINDAIVNVARAWNAVPSQVFQRAWRKL 385
[Close]
BLAST of HTH CENPB-type domain-containing protein vs. Ensembl Mouse
Match: Tigd4 (tigger transposable element derived 4 [Source:MGI Symbol;Acc:MGI:2685264])

HSP 1 Score: 92.4337 bits (228), Expect = 2.082e-20
Identity = 56/171 (32.75%), Postives = 92/171 (53.80%), Query Frame = 1 
Query:   34 NNYTKEQIFNVDETGLYWKRMPERTYIHKEEKSMPGFKAFKDRITVLLGGNIVGY-KLKPFVVHRSKNPRAFKGVKRNMLPVNYNSNKSAWMTQLLFEDWFMNVFATEVKEYCNQHKIPFRILLLLDNAXXXXXXXXXXXXNIQIMYLPPNTTSILQPMDQGAIATFKAHY 543
            N+Y  + +FNV ETGL ++ +P  T+  K E    G K  KDRIT+ LG N+ G  KL   ++ +++ PR FKG+K   LPV Y +N++AWMT  +FE W   +     +++  Q +   R+++ +D+             +I++ + P   +S    M+QG I + K  Y
Sbjct:  172 NDYHPKNVFNVKETGLLYRMLPTNTFAFKGETCSVG-KLCKDRITLALGTNMDGSEKLPLLIIGKNRAPRCFKGIKS--LPVYYEANRTAWMTAAIFEQWMQKL----DEKFQAQKR---RVVIFVDSC--PAHPEVKNLKSIELAFFPSCLSSGFAAMNQGVIKSLKIKY 330
[Close]
BLAST of HTH CENPB-type domain-containing protein vs. Ensembl Mouse
Match: Tigd5 (tigger transposable element derived 5 [Source:MGI Symbol;Acc:MGI:2145902])

HSP 1 Score: 81.2629 bits (199), Expect = 1.210e-16
Identity = 43/133 (32.33%), Postives = 71/133 (53.38%), Query Frame = 1 
Query:   31 ENNYTKEQIFNVDETGLYWKRMPERTYIHKEEKSM-PGFKAFK---DRITVLLGGNIVG-YKLKPFVVHRSKNPRAFKGVKRNMLPVNYNSNKSAWMTQLLFEDWFMNVFATEVKEYCNQHKIPFRILLLLDN 414
            E  Y  EQI+N + TGLYW+ +PE+        S  PG  + +   DR+TVLL  N+ G +KLKP V+ +  +P + +   ++  P +Y  +  AW+++ L   WF   F   VK Y  +  +  + +LL+ +
Sbjct:  235 EGGYGDEQIYNANVTGLYWRLLPEQASTPGTGDSKEPGGCSRRWRSDRVTVLLAANLTGSHKLKPLVIGQLPDPPSLRHHNQDKFPASYRYSPDAWLSRPLLRGWFFEEFVPGVKRYLRRSCLQQKAVLLVAH 367
[Close]
BLAST of HTH CENPB-type domain-containing protein vs. UniProt/SwissProt
Match: sp|Q96MW7|TIGD1_HUMAN (Tigger transposable element-derived protein 1 OS=Homo sapiens OX=9606 GN=TIGD1 PE=1 SV=1)

HSP 1 Score: 206.838 bits (525), Expect = 1.556e-66
Identity = 101/184 (54.89%), Postives = 134/184 (72.83%), Query Frame = 1 
Query:   19 EFLEENNYTKEQIFNVDETGLYWKRMPERTYIHKEEKSMPGFKAFKDRITVLLGGNIVG-YKLKPFVVHRSKNPRAFKGVKRNMLPVNYNSNKSAWMTQLLFEDWFMNVFATEVKEYCNQHKIPFRILLLLDNAXXXXXXXXXXXXNIQIMYLPPNTTSILQPMDQGAIATFKAHYLINYIHSS 567
            + ++E  YTK+QIFNVDET  YWK+MP RT+I +EEKS+PGFKA KDR+T+LLG N  G +KLKP +++ S+NPRA K   ++ LPV Y  N  A MT  LF  WF   F   V+ YC++ KIPF+ILLL+DNAP HP  L +++  I ++++P NTTSILQPMDQG I+TFK++YL N  H +
Sbjct:  171 KIIDEGGYTKQQIFNVDETAFYWKKMPSRTFIAREEKSVPGFKASKDRLTLLLGANAAGDFKLKPMLIYHSENPRALKNYTKSTLPVLYKWNSKARMTAHLFTAWFTEYFKPTVETYCSEKKIPFKILLLIDNAPSHPRALMEIYEEINVIFMPANTTSILQPMDQGVISTFKSYYLRNTFHKA 354

HSP 2 Score: 68.5514 bits (166), Expect = 1.556e-66
Identity = 41/124 (33.06%), Postives = 68/124 (54.84%), Query Frame = 2 
Query:  554 TFTQAIMAIEEGIT-------LKEFWSKFNILQGIINLASGWKEVKASCMSGIWKKLTKI----FEESRSSSIEKEVDVEEITDQIVDLGWQLNLEVDSEDINQLIAHQLDDLANEDLLEFEAQ 892
            TF +A+ A++  ++       LK FW  F IL  I N+   W+EVK S ++G+WKKL       +E  ++S       VEE++  +V++  +L LEV+ ED+ +L+      L +E+L   +AQ
Sbjct:  350 TFHKALAAMDSDVSDGSGQSKLKTFWKGFTILDAIKNIRDSWEEVKLSTLTGVWKKLIPTLIDDYEGFKTS-------VEEVSADVVEIAKELELEVEPEDVTELLQSHDKTLTDEELFLMDAQ 466
[Close]
BLAST of HTH CENPB-type domain-containing protein vs. UniProt/SwissProt
Match: sp|Q9Y4A0|JERKL_HUMAN (Jerky protein homolog-like OS=Homo sapiens OX=9606 GN=JRKL PE=2 SV=2)

HSP 1 Score: 149.058 bits (375), Expect = 9.743e-42
Identity = 78/184 (42.39%), Postives = 110/184 (59.78%), Query Frame = 1 
Query:    1 FVVKFNEFLEENNYTKEQIFNVDETGLYWKRMPERTYIHKEEKSMPGFKAFKDRITVLLGGNIVG-YKLKPFVVHRSKNPRAFKGVKRNMLPVNYNSNKSAWMTQLLFEDWFMNVFATEVKEYCNQHKIPFRILLLLDNAXXXXXXXXXXXXNIQIM--YLPPNTTSILQPMDQGAIATFKAHY 543
            F   F +F+E  N   EQI+N DETGL+WK +P R  + K + ++PG K+ ++R+T++   N  G +KLK  VV ++K PR+FK      LPV+Y S K AWM   +F  WF  +F  +V+EY     +  + +LLLDN+P HP        + QI   YLPPN  S++QP DQG IAT K +Y
Sbjct:  155 FCNNFRDFIERENLQPEQIYNADETGLFWKCLPSRISVIKGKCTVPGHKSIEERVTIMCCANATGLHKLKLCVVGKAKKPRSFKSTDTLNLPVSYFSQKGAWMDLSIFRQWFDKIFVPQVREYLRSKGLQEKAVLLLDNSPTHPNENVLRSDDGQIFAKYLPPNVASLIQPSDQGVIATMKRNY 338

HSP 2 Score: 43.5134 bits (101), Expect = 9.743e-42
Identity = 24/64 (37.50%), Postives = 34/64 (53.12%), Query Frame = 2 
Query:  578 IEEGITLKEFWSKFNILQGIINLASGWKEVKASCMSGIWKKLTKIFEESRSSSIEKEVDVEEIT 769
            +EEG  LK FW K  +L  +  +A  W  VK   +S  WKK+  + EE  S     + DVE+I+
Sbjct:  347 LEEGNDLKSFWKKLTLLDALYEIAMAWNLVKPVTISRAWKKILPMVEEKESL----DFDVEDIS 406
[Close]
BLAST of HTH CENPB-type domain-containing protein vs. UniProt/SwissProt
Match: sp|B2RRL2|JERKL_MOUSE (Jerky protein homolog-like OS=Mus musculus OX=10090 GN=Jrkl PE=2 SV=1)

HSP 1 Score: 146.362 bits (368), Expect = 1.103e-39
Identity = 78/190 (41.05%), Postives = 111/190 (58.42%), Query Frame = 1 
Query:    1 FVVKFNEFLEENNYTKEQIFNVDETGLYWKRMPERTYIHKEEKSMPGFKAFKDRITVLLGGNIVG-YKLKPFVVHRSKNPRAFKGVKRNMLPVNYNSNKSAWMTQLLFEDWFMNVFATEVKEYCNQHKIPFRILLLLDNAXXXXXXXXXXXXNIQIM--YLPPNTTSILQPMDQGAIATFKAHYLINYIH 561
            F   F +F+E+ N   EQI+N DETGL+WK +P RT + K + ++PG    ++RITV+   N  G +KLK  VV +++ PR+FK      LPV+Y S K AWM   +F  WF  +F  +V+EY     +  + +LLLDN+P HP        + QI   YLPPN  S++QP+ QG IA  K +Y    +H
Sbjct:  155 FCNNFRDFIEQENLQPEQIYNADETGLFWKCLPSRTTVIKGKCTVPGHNLGEERITVMCCTNATGLHKLKLCVVGKARKPRSFKSTDTLNLPVSYFSQKGAWMDLSIFRQWFDKIFVPQVREYLRSKGLQEKAVLLLDNSPTHPNENVLRSDDGQIFAKYLPPNVASLIQPLGQGVIAAMKRNYRAGLLH 344

HSP 2 Score: 39.2762 bits (90), Expect = 1.103e-39
Identity = 18/48 (37.50%), Postives = 25/48 (52.08%), Query Frame = 2 
Query:  578 IEEGITLKEFWSKFNILQGIINLASGWKEVKASCMSGIWKKLTKIFEE 721
            +EEG  LK FW K  +L  +  +A  W  VK   +S  WK++    EE
Sbjct:  347 LEEGNDLKSFWKKLTLLDALYEIAMAWNLVKPVTISRAWKQILPAIEE 394
[Close]
BLAST of HTH CENPB-type domain-containing protein vs. UniProt/SwissProt
Match: sp|Q4W5G0|TIGD2_HUMAN (Tigger transposable element-derived protein 2 OS=Homo sapiens OX=9606 GN=TIGD2 PE=3 SV=1)

HSP 1 Score: 140.198 bits (352), Expect = 1.251e-36
Identity = 72/184 (39.13%), Postives = 106/184 (57.61%), Query Frame = 1 
Query:    1 FVVKFNEFLEENNYTKEQIFNVDETGLYWKRMPERTYIHKEEKSMPGFKAFKDRITVLLGGNIVG-YKLKPFVVHRSKNPRAFKGVKRNMLPVNYNSNKSAWMTQLLFEDWFMNVFATEVKEYCNQHKIPFRILLLLD--NAXXXXXXXXXXXXNIQIMYLPPNTTSILQPMDQGAIATFKAHY 543
            F   F EF+E+ N   EQI+  D+TGL+WK +P RT   + ++S  G ++ ++RI ++   N  G +KL   VV ++K PRAFKG   + LPV Y S K AW+ Q +F  WF   F  +V+++     +  + +LLLD   A  +   L      I + YLPPN TS++QPM QG +AT K +Y
Sbjct:  155 FCGSFQEFVEKENLQPEQIYGADQTGLFWKCLPSRTLTLETDQSTSGCRSSRERIIIMCCANATGLHKLNLCVVGKAKKPRAFKGTDLSNLPVTYYSQKGAWIEQSVFRQWFEKYFVPQVQKHLKSKGLLEKAVLLLDFPPARPNEEMLSSDDGRIIVKYLPPNVTSLIQPMSQGVLATVKRYY 338

HSP 2 Score: 35.039 bits (79), Expect = 1.251e-36
Identity = 18/55 (32.73%), Postives = 29/55 (52.73%), Query Frame = 2 
Query:  578 IEEGITLKEFWSKFNILQGIINLASGWKEVKASCMSGIWKKLTKIFEESRSSSIE 742
            ++EG   K FW    +L  I  ++  W  VK+S ++  WKKL    EE+   +I+
Sbjct:  347 MDEGNDPKIFWKNLTVLDAIYEVSRAWNMVKSSTITKAWKKLFPGNEENSGMNID 401
[Close]
BLAST of HTH CENPB-type domain-containing protein vs. UniProt/SwissProt
Match: sp|Q0VBL1|TIGD2_MOUSE (Tigger transposable element-derived protein 2 OS=Mus musculus OX=10090 GN=Tigd2 PE=2 SV=1)

HSP 1 Score: 133.265 bits (334), Expect = 3.462e-35
Identity = 70/190 (36.84%), Postives = 102/190 (53.68%), Query Frame = 1 
Query:    1 FVVKFNEFLEENNYTKEQIFNVDETGLYWKRMPERTYIHKEEKSMPGFKAFKDRITVLLGGNIVG-YKLKPFVVHRSKNPRAFKGVKRNMLPVNYNSNKSAWMTQLLFEDWFMNVFATEVKEYCNQHKIPFRILLLLD--NAXXXXXXXXXXXXNIQIMYLPPNTTSILQPMDQGAIATFKAHYLINYIH 561
            F   F EF+E  N   EQI+  D+TGL+WK +P RT     ++S   ++  ++RI ++   N  G +KL   VV ++K PRAFKG   + LPV Y S KSAW+   + + WF   F  +V+++     +  + +LLLD   A      L      I + YLPPN TS++QPM QG + T K +Y    I 
Sbjct:  155 FCGNFQEFVERENLLPEQIYGADQTGLFWKCLPTRTLAFDTDQSTCEYRTSRERIIIMCCANATGSHKLNLCVVGKAKRPRAFKGTDLSNLPVTYFSQKSAWIEPSVLKQWFEKCFVPQVQKHLKSKGLREKAVLLLDFPAAHPAEELLSSDDGRIIVKYLPPNVTSLIQPMSQGVLTTVKRYYRAGLIQ 344

HSP 2 Score: 37.3502 bits (85), Expect = 3.462e-35
Identity = 17/55 (30.91%), Postives = 30/55 (54.55%), Query Frame = 2 
Query:  578 IEEGITLKEFWSKFNILQGIINLASGWKEVKASCMSGIWKKLTKIFEESRSSSIE 742
            ++EG   K FW    +L  I   +  W +++++ ++  WKKL    EE+ S SI+
Sbjct:  347 MDEGNDPKTFWKNLTVLDAIYEASRAWNQIRSNTITRAWKKLFPGNEENPSVSID 401
[Close]
BLAST of HTH CENPB-type domain-containing protein vs. TrEMBL
Match: K7GFF7 (HTH CENPB-type domain-containing protein OS=Pelodiscus sinensis OX=13735 PE=4 SV=1)

HSP 1 Score: 240.35 bits (612), Expect = 3.123e-83
Identity = 115/184 (62.50%), Postives = 149/184 (80.98%), Query Frame = 1 
Query:    1 FVVKFNEFLEENNYTKEQIFNVDETGLYWKRMPERTYIHKEEKSMPGFKAFKDRITVLLGGNIVGYKLKPFVVHRSKNPRAFKGVKRNMLPVNYNSNKSAWMTQLLFEDWFMNVFATEVKEYCNQHKIPFRILLLLDNAXXXXXXXXXXXXNIQIMYLPPNTTSILQPMDQGAIATFKAHYLIN 552
            F+ + ++ ++E NY  EQIFNVDETGL+WK+MPE TYIH+E K+MPG+KAFKD +TV+LGGN+ GYKLKP + +RS+NPRAFK + +  LPV+Y +NK AW+T  LFEDWFMN F  EVK Y  +  IPF+IL +LDNAPGHP +L  L+ ++++++LPPNTTSILQPMDQGAIA FKA+YL N
Sbjct:  168 FIEELDKLIKEGNYFPEQIFNVDETGLFWKKMPEHTYIHREAKTMPGYKAFKDHLTVMLGGNVSGYKLKPLLNYRSENPRAFKNISKATLPVHYRANKKAWLTLALFEDWFMNCFIPEVKSYFLEKGIPFQILFILDNAPGHPQYLNYLNSDVKVVFLPPNTTSILQPMDQGAIAAFKAYYLRN 351

HSP 2 Score: 98.5969 bits (244), Expect = 3.123e-83
Identity = 51/112 (45.54%), Postives = 76/112 (67.86%), Query Frame = 2 
Query:  554 TFTQAIMAIE--EGITLKEFWSKFNILQGIINLASGWKEVKASCMSGIWKKLTKIFEESRSSSIEKEVDVEEITDQIVDLGWQLNLEVDSEDINQLIAHQLDDLANEDLLEF 883
            +F +A+ A E   G TL EFW  +NIL  I N+A+GW+EV   CM+GIWKK+ K F        EKE ++E+I++ IV L  +++LE+D+EDI+QL+    D+L+NEDL++ 
Sbjct:  352 SFAKAVTATECENGKTLPEFWKDYNILHCIRNIAAGWEEVTPQCMNGIWKKILKRFVNC-FEGFEKEKELEDISNNIVQLAKEVDLEMDNEDIHQLVEDVGDELSNEDLMQL 462
[Close]
BLAST of HTH CENPB-type domain-containing protein vs. TrEMBL
Match: K7GC45 (Uncharacterized protein OS=Pelodiscus sinensis OX=13735 PE=4 SV=1)

HSP 1 Score: 234.187 bits (596), Expect = 3.411e-81
Identity = 117/184 (63.59%), Postives = 148/184 (80.43%), Query Frame = 1 
Query:    1 FVVKFNEFLEENNYTKEQIFNVDETGLYWKRMPERTYIHKEEKSMPGFKAFKDRITVLLGGNIVGYKLKPFVVHRSKNPRAFKGVKRNMLPVNYNSNKSAWMTQLLFEDWFMNVFATEVKEYCNQHKIPFRILLLLDNAXXXXXXXXXXXXNIQIMYLPPNTTSILQPMDQGAIATFKAHYLIN 552
            F+ + ++ ++E NY  E IFNVDETGL+WK+ PE TYIHKE K+MPG+K FKDR+TVLLGGN+ GYKLKP +++RS+NPRAFK + +  LPV+Y+ NK AWMT  LFEDWFMN F  EVK Y  +  IPF+ILL+LDNAPGHP +L DLH ++++++LPPNTTSILQPMDQ AIA FKA+ L N
Sbjct:  144 FIEELDKLIKEGNYFPEHIFNVDETGLFWKKTPECTYIHKEAKTMPGYKPFKDRLTVLLGGNVSGYKLKPLLIYRSENPRAFKNISKATLPVHYHINKKAWMTLALFEDWFMNCFIPEVKSYFLKKGIPFQILLILDNAPGHPQYLNDLHSDLKVVFLPPNTTSILQPMDQKAIAAFKAYDLRN 327

HSP 2 Score: 97.8265 bits (242), Expect = 3.411e-81
Identity = 53/115 (46.09%), Postives = 78/115 (67.83%), Query Frame = 2 
Query:  554 TFTQAIMAIE--EGITLKEFWSKFNILQGIINLASGWKEVKASCMSGIWKKLTKIFEESRSSSIEKEVDVEEITDQIVDLGWQLNLEVDSEDINQLIAHQLDDLANEDLLEFEAQ 892
            TF +A+ A E   G TL EFW  +NIL  I N+A+GW+EV + CM+ IWKK+ K F      S EKE  +E+I++ IV L  ++ LE+D+EDI+QL+    ++L+NEDL++ EA+
Sbjct:  328 TFAKAVAATECKNGKTLHEFWKDYNILHCIRNIAAGWEEVTSQCMNCIWKKILKRFVNC-FKSFEKEKALEDISNNIVQLAKEVALEMDNEDIHQLVEDVGEELSNEDLMQLEAE 441
[Close]
BLAST of HTH CENPB-type domain-containing protein vs. TrEMBL
Match: A0A452GZM6 (HTH CENPB-type domain-containing protein OS=Gopherus agassizii OX=38772 PE=4 SV=1)

HSP 1 Score: 233.417 bits (594), Expect = 1.715e-79
Identity = 113/179 (63.13%), Postives = 147/179 (82.12%), Query Frame = 1 
Query:   13 FNEFLEENNYTKEQIFNVDETGLYWKRMPERTYIHKEEKSMPGFKAFKDRITVLLGGNIVG-YKLKPFVVHRSKNPRAFKGVKRNMLPVNYNSNKSAWMTQLLFEDWFMNVFATEVKEYCNQHKIPFRILLLLDNAXXXXXXXXXXXXNIQIMYLPPNTTSILQPMDQGAIATFKAHYL 546
              + +EE  YT +QIFNVDETGL+WK+MPERTYI KEEK+MPGFKA KDR+T+LLGGN  G  KLKP +V+ S+NP AFKG+ +  LPV++ SN+ AW+T  LFEDWF+N+F  E +++C ++ IPF+I+L++DNAPGHP HL D HPN+++++LPPNTTSILQPMDQG IA FKA+YL
Sbjct:  174 LRKLIEECGYTAQQIFNVDETGLFWKKMPERTYISKEEKTMPGFKAAKDRLTLLLGGNAAGDCKLKPLLVYHSENPHAFKGISKATLPVHFRSNRKAWITMALFEDWFINLFIPEAEKFCRENDIPFKIMLIVDNAPGHPAHLDDFHPNVKVVFLPPNTTSILQPMDQGVIANFKAYYL 352

HSP 2 Score: 92.8189 bits (229), Expect = 1.715e-79
Identity = 52/119 (43.70%), Postives = 71/119 (59.66%), Query Frame = 2 
Query:  554 TFTQAIMAI--EEGITLKEFWSKFNILQGIINLASGWKEVKASCMSGIWKKLTKIFEESRSSSIEKEVDVEEITDQIVDLGWQLNLEVDSEDINQLIAHQLDDLANEDLLEFEAQCVGE 904
            TF QA+ A   E G TL++FW  +NI Q IIN+A  W EV    ++ +WKK+   F  S     EK+   EE+ D+IV L  QL LE+D  D+++LI     +L+NEDL+E EA  V E
Sbjct:  355 TFAQAVKATDRESGKTLRDFWKSYNIYQAIINIAKAWAEVTQVRLNAVWKKVCPQFVHS-FKVFEKDETYEEVADEIVKLAEQLELEIDVGDVDELIESHGAELSNEDLIELEAAKVKE 472
[Close]
BLAST of HTH CENPB-type domain-containing protein vs. TrEMBL
Match: A0A452GH56 (HTH CENPB-type domain-containing protein OS=Gopherus agassizii OX=38772 PE=4 SV=1)

HSP 1 Score: 214.927 bits (546), Expect = 2.991e-76
Identity = 107/179 (59.78%), Postives = 143/179 (79.89%), Query Frame = 1 
Query:   13 FNEFLEENNYTKEQIFNVDETGLYWKRMPERTYIHKEEKSMPGFKAFKDRITVLLGGNIVG-YKLKPFVVHRSKNPRAFKGVKRNMLPVNYNSNKSAWMTQLLFEDWFMNVFATEVKEYCNQHKIPFRILLLLDNAXXXXXXXXXXXXNIQIMYLPPNTTSILQPMDQGAIATFKAHYL 546
              + +EE  YT +QIFNV+ETGL+WK+MP+RTYI KEEK+ PGFKA KD++T+LLGGN  G  KLKP +V+ S+NPRAFKG+    LPV++ S++ AW+T  LFEDWF+N+F  EV+++C ++ IPF+I+L++DNAPGHP HL D HPN+++++LP N TSILQPM QG IA FKA YL
Sbjct:  174 LRKLIEEYGYTAQQIFNVNETGLFWKKMPDRTYISKEEKTTPGFKAVKDKLTLLLGGNAAGDCKLKPLLVYHSENPRAFKGISEVNLPVHFRSDRKAWITMALFEDWFINLFIPEVEKFCRENDIPFKIMLIVDNAPGHPAHLDDFHPNVKVVFLPLNKTSILQPMAQGVIANFKACYL 352

HSP 2 Score: 100.908 bits (250), Expect = 2.991e-76
Identity = 54/119 (45.38%), Postives = 72/119 (60.50%), Query Frame = 2 
Query:  554 TFTQAIMAI--EEGITLKEFWSKFNILQGIINLASGWKEVKASCMSGIWKKLTKIFEESRSSSIEKEVDVEEITDQIVDLGWQLNLEVDSEDINQLIAHQLDDLANEDLLEFEAQCVGE 904
            TF QA+ A   E G TL +FW  +NI Q IIN+A  W+EV   C++ +WKK+   F  S     EK+   EE+ D+IV L  QL LE+D  D++Q I    D+L+NEDL+E EA  V E
Sbjct:  355 TFAQAVEATDRETGKTLHDFWKSYNIYQAIINIAKAWEEVTQVCLNAVWKKMCPQFVHS-FKGFEKDKTYEEVADEIVKLAEQLELEIDVGDVDQFIESHGDELSNEDLMELEAAKVKE 472
[Close]
BLAST of HTH CENPB-type domain-containing protein vs. TrEMBL
Match: M7BBU3 (Uncharacterized protein (Fragment) OS=Chelonia mydas OX=8469 GN=UY3_07369 PE=4 SV=1)

HSP 1 Score: 221.861 bits (564), Expect = 3.202e-76
Identity = 108/179 (60.34%), Postives = 146/179 (81.56%), Query Frame = 1 
Query:   13 FNEFLEENNYTKEQIFNVDETGLYWKRMPERTYIHKEEKSMPGFKAFKDRITVLLGGNIVG-YKLKPFVVHRSKNPRAFKGVKRNMLPVNYNSNKSAWMTQLLFEDWFMNVFATEVKEYCNQHKIPFRILLLLDNAXXXXXXXXXXXXNIQIMYLPPNTTSILQPMDQGAIATFKAHYL 546
              + +EE  YT +QIFNVDETGL+WK+MP+RT I KEEK MPGFKA KDR+T+LLGGN  G  KLKP +V+ S+NP AFKG+ +  LPV++ SN+ AW+T  LF+DWF+N+F  EV+++C ++ IPF+I+L++DNAPGHP +L D HPN+++++LPPNTTS+LQPMD+G IA FKA+YL
Sbjct:  161 LRKLIEEYGYTAQQIFNVDETGLFWKKMPDRTNISKEEKMMPGFKASKDRLTLLLGGNAAGDCKLKPLLVYHSENPCAFKGISKATLPVHFRSNRKAWITMALFKDWFINLFIPEVEKFCRENDIPFKIMLIVDNAPGHPANLDDFHPNVKVVFLPPNTTSLLQPMDKGVIANFKAYYL 339

HSP 2 Score: 93.5893 bits (231), Expect = 3.202e-76
Identity = 51/113 (45.13%), Postives = 68/113 (60.18%), Query Frame = 2 
Query:  554 TFTQAIMAI--EEGITLKEFWSKFNILQGIINLASGWKEVKASCMSGIWKKLTKIFEESRSSSIEKEVDVEEITDQIVDLGWQLNLEVDSEDINQLIAHQLDDLANEDLLEFE 886
            TF QA+ A   E G TL++FW  +NI Q IIN+A  W EV   C++ +WKK    F  S     EK+   EE+ D+IV L  QL LEVD  D+++LI     +L+NEDL+E E
Sbjct:  342 TFAQAVEATGRETGKTLRDFWKSYNIYQAIINIAKAWAEVTQVCLNAVWKKACPQFVRS-FKGFEKDETYEEVADEIVKLAKQLELEVDIGDVDELIESHGAELSNEDLMELE 453
[Close]
BLAST of HTH CENPB-type domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004972.1 (pep scaffold:Pmarinus_7.0:GL476545:74372:75575:-1 gene:ENSPMAG00000004517.1 transcript:ENSPMAT00000004972.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 189.889 bits (481), Expect = 4.267e-58
Identity = 98/176 (55.68%), Postives = 129/176 (73.30%), Query Frame = 1 
Query:    1 FVVKFNEFLEENNYTKEQIFNVDETGLYWKRMPERTYIHKEEKSMPGFKAFKDRITVLLGGNIVGYKLKPFVVHRSKNPRAFKGVKRNMLPVNYNSNKSAWMTQLLFEDWFMNVFATEVKEYCNQHKIPFRILLLLDNAXXXXXXXXXXXXNIQIMYLPPNTTSILQPMDQGAIAT 528
            F  + ++ + E NY  EQIFNVDETG              + K+M GFKAFKDR+T+LLGGN+  YKLKPF+++ S N RA   + +NMLPV+Y  NK AWMT +LFEDWF+N F  EVKE+C ++ IPF+I+L+LDNAPGH  ++GD  PN+ +++LPPNTTSI+QPMDQGA+AT
Sbjct:  147 FKGELHKIIVEENYLPEQIFNVDETGT-------------DAKTMAGFKAFKDRLTLLLGGNVAVYKLKPFMIYHSTNARALARISKNMLPVHYRHNKKAWMTAVLFEDWFVNCFIPEVKEHCRKNGIPFKIMLILDNAPGHLQYIGDNDPNV-VVFLPPNTTSIIQPMDQGAVAT 308

HSP 2 Score: 46.595 bits (109), Expect = 3.794e-6
Identity = 18/40 (45.00%), Postives = 25/40 (62.50%), Query Frame = 2 
Query:  596 LKEFWSKFNILQGIINLASGWKEVKASCMSGIWKKLTKIF 715
            L+  W + N+L  I N+   WKEV   CM+GIWK L K++
Sbjct:  324 LRMIWKESNVLNAIRNIGRAWKEVTKECMNGIWKNLLKVY 363
[Close]
BLAST of HTH CENPB-type domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000005921.1 (pep scaffold:Pmarinus_7.0:GL487978:976:2666:1 gene:ENSPMAG00000005352.1 transcript:ENSPMAT00000005921.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 122.479 bits (306), Expect = 5.399e-45
Identity = 61/106 (57.55%), Postives = 82/106 (77.36%), Query Frame = 1 
Query:  229 KNPRAFKGVKRNMLPVNYNSNKSAWMTQLLFEDWFMNVFATEVKEYCNQHKIPFRILLLLDNAXXXXXXXXXXXXNIQIMYLPPNTTSILQPMDQGAIATFKAHYL 546
            +NPRAFKG+ +  LPV + +N +AW+T  +FEDWF+N F  +V++YC    IPF+ILL++DNAP HP HL D HPNI++++LPPN TS+LQPMDQG  A  KA+YL
Sbjct:  189 ENPRAFKGISKATLPVYFRANPTAWVTVAIFEDWFINCFIPDVEKYCRDEGIPFKILLVIDNAPSHPAHLDDFHPNIKVVFLPPNATSVLQPMDQGVNAKCKAYYL 294

HSP 2 Score: 75.8702 bits (185), Expect = 5.399e-45
Identity = 46/136 (33.82%), Postives = 69/136 (50.74%), Query Frame = 2 
Query:  554 TFTQAIMAIE--EGITLKEFWSKFNILQGIINLASGWKEVKASCMSGIWKKLTKIFE------ESRSSSIEKEVDVEEITDQIVDLGWQLNLEVDSEDINQLIAHQLDDLANEDL-LEFEAQCVGENVDKGKSDEE 934
            T  QA+ A E   G T++EFW  +++ Q + N+A  W EV  +C++G W+K+            +R      E    E+   IV L  +L LEVD+ D+ +LI     +L+NEDL  +FEA  V E      +DE 
Sbjct:  297 TLAQALEATEGDTGKTVREFWEAYDVYQAVQNIAKAWAEVTQTCLNGAWEKMCPQLAAAAAAVHARRGPQNDETHA-EVAQSIVTLAAELRLEVDAADVEELIESHGAELSNEDLAAQFEAAKVAEEARDEPADEP 431
[Close]
BLAST of HTH CENPB-type domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000003106.1 (pep scaffold:Pmarinus_7.0:GL476998:37517:41189:1 gene:ENSPMAG00000002845.1 transcript:ENSPMAT00000003106.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 107.071 bits (266), Expect = 1.293e-41
Identity = 53/107 (49.53%), Postives = 76/107 (71.03%), Query Frame = 1 
Query:  226 SKNPRAFKGVKRNMLPVNYNSNKSAWMTQLLFEDWFMNVFATEVKEYCNQHKIPFRILLLLDNAXXXXXXXXXXXXNIQIMYLPPNTTSILQPMDQGAIATFKAHYL 546
            ++NPRA KG  +N LPV + SN  A +T  +FE+WF   F   VKEYC  + + F+ +L+LDNAP HP  +    PNI++++L PNTT++LQPMDQG +++FKA+YL
Sbjct:  181 TENPRALKGYTKNTLPVIWKSNPKARVTGAIFEEWFRVYFVPAVKEYCRTNNLAFKAILVLDNAPCHPVSVEGFDPNIKVVFLTPNTTALLQPMDQGVMSSFKAYYL 287

HSP 2 Score: 80.1073 bits (196), Expect = 1.293e-41
Identity = 53/120 (44.17%), Postives = 76/120 (63.33%), Query Frame = 2 
Query:  554 TFTQAIMAI--EEGITLKEFWSKFNILQGIINLASGWKEVKASCMSGIWKKLTKIFEESRSSSIEKEVD-VEEITDQIVDLGWQLNLEVDSEDINQLIAHQLDDLANEDLLEFEAQCVGE 904
            TF QAI A   E G TL EFW  F+IL  + N+A+ WKE+K S ++G+W+KL   F     S+ +   D VEE+T+ +V++  QL LEV  ED+ +L+A    +L+NEDLL+ E Q + E
Sbjct:  290 TFAQAISATDKEGGPTLTEFWKGFSILDAVKNIAASWKEMKQSNLNGVWRKLCPEF----VSNFQGFTDTVEEVTENVVEMAGQLQLEVAPEDVGELLASHAHELSNEDLLQLEQQRLEE 405
[Close]
BLAST of HTH CENPB-type domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000005656.1 (pep scaffold:Pmarinus_7.0:GL476578:539135:542172:1 gene:ENSPMAG00000005132.1 transcript:ENSPMAT00000005656.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 147.132 bits (370), Expect = 1.315e-40
Identity = 67/140 (47.86%), Postives = 92/140 (65.71%), Query Frame = 1 
Query:    1 FVVKFNEFLEENNYTKEQIFNVDETGLYWKRMPERTYIHKEEKSMPGFKAFKDRITVLLGGNIVG-YKLKPFVVHRSKNPRAFKGVKRNMLPVNYNSNKSAWMTQLLFEDWFMNVFATEVKEYCNQHKIPFRILLLLDNA 417
            F     E +E   Y+ EQ+FNV+ETGL+WKRMP  T++ +EEK+ PGFKA KDR+ +L+G N  G  KLKP +V+ SK PRA KG  +  LPV + SNK  W+T  +F DW  N F   +++YC +  +  + LLLL+NA
Sbjct:  166 FKSTLKEIIEGGGYSPEQVFNVNETGLFWKRMPASTFLSREEKTAPGFKASKDRLALLVGANAAGDCKLKPLLVYHSKTPRALKGCIKADLPVIWRSNKKGWITASVFLDWLKNHFCPAIEKYCKKKNLDHKALLLLNNA 305
[Close]
BLAST of HTH CENPB-type domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000003283.1 (pep scaffold:Pmarinus_7.0:GL479064:1419:3178:1 gene:ENSPMAG00000003000.1 transcript:ENSPMAT00000003283.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 140.198 bits (352), Expect = 1.163e-38
Identity = 71/143 (49.65%), Postives = 98/143 (68.53%), Query Frame = 1 
Query:  121 EEKSMPGFKAFKDRITVLLGGNIVG-YKLKPFVVHRSKNPRAFKGVKRNMLPVNYNSNKSAWMTQLLFEDWFMNVFATEVKEYCNQHKIPFRILLLLDNAXXXXXXXXXXXXNIQIMYLPPNTTSILQPMDQGAIATFKAHYL 546
            +  + PG +A KDR+TV+LG N  G Y+LKP VVH S NPR  KG  R  L V++ S+K  WMT  +F D+ +     E++ YC +    F+ILL++DNAP HPP++ DL   I++++LPP+TTS+LQPM QG IA FKA+YL
Sbjct:  176 DRATAPGLRAAKDRLTVMLGANASGGYRLKPVVVHHSANPRTLKGFVRADLGVHFRSSKRGWMTDQMFTDYVLETLQDELRRYCKRKNQDFKILLVVDNAPSHPPYIVDLSEQIKVVFLPPHTTSLLQPMGQGVIAAFKAYYL 318

HSP 2 Score: 36.965 bits (84), Expect = 1.163e-38
Identity = 18/67 (26.87%), Postives = 34/67 (50.75%), Query Frame = 2 
Query:  608 WSKFNILQGIINLASGWKEVKASCMSGIWKKLTKIFEESRSSSIEKEVDVEEITDQIVDLGWQLNLE 808
            W  FNI Q I  +   W ++   C++G+ +KL  +  + R+   ++E  +++I  Q V L  +   E
Sbjct:  340 WRSFNIKQAIDIIVEAWTDITQPCLNGVCRKLPHVVRDFRAFEAQQE-QLKKIQIQCVALARRAGFE 405
[Close]
BLAST of HTH CENPB-type domain-containing protein vs. Ensembl Nematostella
Match: EDO44738 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RUQ6])

HSP 1 Score: 79.7221 bits (195), Expect = 7.670e-17
Identity = 54/171 (31.58%), Postives = 86/171 (50.29%), Query Frame = 1 
Query:   34 NNYTKEQIFNVDETGLYWKRMPERTYIHKEEKSMPGFKAFKDRITVLLGGNIVGYKLKPFVVHRSKNPRAFKGVKRNMLPVNYNSNKSAWMTQLLFEDWFMNVFATEVKEYCNQHKIPFRILLLLDNAXXXXXXXXXXXXNIQIMYLPP-NTTSILQPMDQGAIATFKAHY 543
            + Y    I+N+ ETGLY++ +P++  + + E +        +R+TV L  N+ G   KP V+  + NP  F  +    LPV + +N+ AW+T  +F DW   +            +   RILL LDN+P HPP L   +  +  +  P  NT + LQP+ QG +  F+  Y
Sbjct:  156 DGYRSTDIYNLVETGLYYRALPDKNLVPETESTS------TERLTVTLCCNMDGEFEKPLVIGPTANPPCFAKLDSECLPVIWRANRRAWITTSIFADWLRTLDR-------KMRQKDRRILLFLDNSPPHPPTLQLTNVKLVFLIKPSNNTVNQLQPLTQGIVEAFRMAY 313
[Close]
BLAST of HTH CENPB-type domain-containing protein vs. Ensembl Nematostella
Match: EDO40000 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S8J7])

HSP 1 Score: 69.3218 bits (168), Expect = 9.842e-14
Identity = 51/153 (33.33%), Postives = 79/153 (51.63%), Query Frame = 1 
Query:   34 NNYTKEQIFNVDETGLYWKRMPERTYIHKEEKSMPGFKAFKDRITVLLGGNIVGYKLKPFVVHRSKNPRAFKGVKRNMLPVNYNSNKSAWMTQL-LFEDWFMNVFATEVKEYCNQHKIPFR-ILLLLDNAXXXXXXXXXXXXNIQIMYLPPNT 486
            + Y  E +F+ DE GL++K +P++  +H + +S  G K  K R+T L   +  G KL  FV+ +S+ PR F GV+   LP  Y + K  W+    LFE+W        V+E     + P R + L++DN P HP         I ++ LPP +
Sbjct:  120 SKYALEDMFDADEFGLFYKALPDK-LMHLKLQSCVGGKQSKVRLTGLAAASSSGEKLPMFVIGKSQKPRCFSGVRN--LPCRYRAPKKGWILDSNLFEEW--------VREQDRSFERPGRNVALVVDNGPAHPTVSNFKA--IDLILLPPTS 259
[Close]
BLAST of HTH CENPB-type domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000031980.1 (pep primary_assembly:ASM223467v1:3:6881985:6888319:-1 gene:ENSORLG00000025652.1 transcript:ENSORLT00000031980.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 186.037 bits (471), Expect = 5.744e-56
Identity = 94/184 (51.09%), Postives = 121/184 (65.76%), Query Frame = 1 
Query:   10 KFNEFLEENNYTKEQIFNVDETGLYWKRMPERTYIHKEEKSMPGFKAFKDRITVLLGGNIVGYKLKPFVVHRSKNPRAFKGVKRNMLPVNYNSNKSAWMTQLLFEDWFMNVFATEVKEYCNQHKIPFRILLLLDNAXXXXXXXXXXXXNIQIMYLPPNTTSILQPMDQGAIATFKAHYLINYIH 561
            KF   +EE  Y  EQIFN+DETGL+WKRMP RT+I +EE   PGFKA KDR+T++  GN  G+ +KP +++RSKNPRA K   ++ L V +  N  AWMT+ L  DWF N F  +VK Y     + F++LLL+DNA GH   L      +QI +LPPNTTS++QPMDQG I  FKA Y  N + 
Sbjct:   96 KFKAIIEEGGYKPEQIFNIDETGLFWKRMPSRTFIMQEEAKAPGFKAQKDRLTLVKCGNAAGFMIKPGLIYRSKNPRALKNKNKDDLHVCWMYNAKAWMTKALNLDWFKNCFIPQVKCYLRGKGLDFKVLLLVDNAGGHADDLAYDC--VQIKFLPPNTTSLIQPMDQGIIRAFKALYTRNTLQ 277
[Close]
BLAST of HTH CENPB-type domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000036785.1 (pep primary_assembly:ASM223467v1:22:11796267:11802170:-1 gene:ENSORLG00000024024.1 transcript:ENSORLT00000036785.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 154.066 bits (388), Expect = 5.675e-43
Identity = 78/185 (42.16%), Postives = 110/185 (59.46%), Query Frame = 1 
Query:    7 VKFNEFLEENNYTKEQIFNVDETGLYWKRMPERTYIHKEEKSMPGFKAFKDRITVLLGGNIVGYKLKPFVVHRSKNPRAFKGVKRNMLPVNYNSNKSAWMTQLLFEDWFMNVFATEVKEYCNQHKIPFRILLLLDNAXXXXXXXXXXXXNIQIMYLPPNTTSILQPMDQGAIATFKAHYLINYIH 561
             KF   ++E  Y  EQ+FN+ ETGL+WK++P +           GF+  KDR+T+++ GN  G+ +KP ++ R KNPRA K    + LPV +  N  AWMT+ L  +WF   F  EVK Y  +  + F++LLL+DNA          H  +QI +LPPNT+S++QPMDQG I TFKA Y  N + 
Sbjct:  141 TKFKTIIKEGTYKPEQVFNMGETGLFWKQIPSQA-------KASGFRGQKDRVTLVMCGNAAGFMIKPGLISRLKNPRALKNKNMSALPVYWMHNTMAWMTKALNLNWFKGCFIPEVKGYLTEKGLDFKVLLLIDNA--GGFADDLSHDGVQIEFLPPNTSSLIQPMDQGIIRTFKALYTRNTLQ 316

HSP 2 Score: 39.6614 bits (91), Expect = 5.675e-43
Identity = 27/109 (24.77%), Postives = 54/109 (49.54%), Query Frame = 2 
Query:  572 MAIEEGITLKEFWSKFNILQGIINLASGWKEVKASCMSGIWKKLTKIFEESRSSSIEKEVD--VEEITDQIVDLGWQLNL----EVDSEDINQLIAHQLDDLANEDLLE 880
            M  ++  + K++W ++ I   + ++    +E+K+  ++G W+KL   + E+  +  E  +D     + +  V L  +L      E+ S+D+N LI      L +EDL E
Sbjct:  322 MDSDQNFSFKDYWREYTIASCLQHIQRAHQEMKSETLNGCWEKL---WPEAVHNPTESRLDEIHRSVVETAVSLAKRLRGDGFDEITSDDVNSLIDAHSQPLTDEDLAE 427
[Close]
BLAST of HTH CENPB-type domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000034610.1 (pep primary_assembly:ASM223467v1:22:20217020:20217298:1 gene:ENSORLG00000027855.1 transcript:ENSORLT00000034610.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 45.4394 bits (106), Expect = 3.952e-6
Identity = 32/69 (46.38%), Postives = 38/69 (55.07%), Query Frame = -3 
Query:    9 TKGFNL*PTIFPPNKTVIRSLKALNPGILFSSL*IYVRSGILFQYRPVSSTLNICSFV*LFSSKNSLNL 215
            + GF + P  F     V  S  ALNPG   SS  I VR GILFQ +PVSS L  CS +   SS  +LN+
Sbjct:    2 SPGFIIKPAGFLHIVRVTLSFWALNPGAFASSCMIKVREGILFQDKPVSSMLKTCSGLYPPSSMMALNV 70
[Close]
BLAST of HTH CENPB-type domain-containing protein vs. Planmine SMEST
Match: SMESG000027161.1 (SMESG000027161.1)

HSP 1 Score: 93.2041 bits (230), Expect = 1.098e-20
Identity = 60/168 (35.71%), Postives = 90/168 (53.57%), Query Frame = 1 
Query:   13 FNEFLEENNYTKEQIFNVDETGLYWKRMPERTYIHK-EEKSMPGFKAFKDRITVLLGGNIVG-YKLKPFVVHRSKNPRAFKGVKRNMLPVNYNSNKSAWMTQLLFEDWFMNVFATEVKEYCNQHKIPFRILLLLDNAXXXXXXXXXXXXNIQIMYLPPNTTSILQPMD 510
              +FLEE  YT +Q++N DET L +K +P RT+  K +     GFK  KDR+T+L   N  G +KL+P ++ +SK PR F  V     P  Y ++ +AWM    F DWF   F  +V+ +  + K+  +  L+LDN P HP     +  + +    P +T S+ Q  D
Sbjct:  353 LKKFLEEGCYTADQVYNCDETDLCYKILPNRTFTTKTDNHKREGFKKRKDRLTLLFCVNKSGSHKLRPLMIGKSKAPRCFYRVNMKSPPFQYINSNNAWMNTTAFYDWFHKTFVPDVRAHLRKLKLEEKA-LILDNCPAHPKRKILIKASPEGKLKPASTMSLPQSRD 519
[Close]
BLAST of HTH CENPB-type domain-containing protein vs. Planmine SMEST
Match: SMESG000029226.1 (SMESG000029226.1)

HSP 1 Score: 89.3521 bits (220), Expect = 2.329e-19
Identity = 59/166 (35.54%), Postives = 89/166 (53.61%), Query Frame = 1 
Query:   49 EQIFNVDETGLYWKRMPERTYIHKEEKSMPGFKAFKDRITVLLGGNIVGY-KLKPFVVHRSKNPRAFKGVKRNMLPVNYNSNKSAWMTQLLFEDWFMNVFATEVKEYCNQHKIPFRILLLLDNAXXXXXXXXXXXXNIQIMYLPPNTTSILQPMDQGAIATFKAHY 543
            E I   +ETGL +K +P +T+  K+EK   G K+ K+RIT+L G +  G  KL P V+ +S  PR  K +  + L   Y SN+  WMT+ +F +    +     K +  +++   +ILL +DN       L     N+++ +   N TS LQPMD+G IA FK  Y
Sbjct: 2331 EDIDKAEETGLLYKCLPNKTFNIKDEKCFNGEKS-KERITILFGCDAAGSDKLTPLVIGKSLKPRCIKLINMSNLGFYYLSNRKTWMTEGVFRESIAKI----DKRFLAKNR---KILLFIDN--FSGHALKSQSNNVKVAFFHLNCTSKLQPMDKGIIANFKLKY 2486
[Close]
BLAST of HTH CENPB-type domain-containing protein vs. Planmine SMEST
Match: SMESG000029226.1 (SMESG000029226.1)

HSP 1 Score: 88.9669 bits (219), Expect = 2.419e-19
Identity = 59/166 (35.54%), Postives = 89/166 (53.61%), Query Frame = 1 
Query:   49 EQIFNVDETGLYWKRMPERTYIHKEEKSMPGFKAFKDRITVLLGGNIVGY-KLKPFVVHRSKNPRAFKGVKRNMLPVNYNSNKSAWMTQLLFEDWFMNVFATEVKEYCNQHKIPFRILLLLDNAXXXXXXXXXXXXNIQIMYLPPNTTSILQPMDQGAIATFKAHY 543
            E I   +ETGL +K +P +T+  K+EK   G K+ K+RIT+L G +  G  KL P V+ +S  PR  K +  + L   Y SN+  WMT+ +F +    +     K +  +++   +ILL +DN       L     N+++ +   N TS LQPMD+G IA FK  Y
Sbjct: 2108 EDIDKAEETGLLYKCLPNKTFNIKDEKCFNGEKS-KERITILFGCDAAGSDKLTPLVIGKSLKPRCIKLINMSNLGFYYLSNRKTWMTEGVFRESIAKI----DKRFLAKNR---KILLFIDN--FSGHALKSQSNNVKVAFFHLNCTSKLQPMDKGIIANFKLKY 2263
[Close]
BLAST of HTH CENPB-type domain-containing protein vs. Planmine SMEST
Match: SMESG000029226.1 (SMESG000029226.1)

HSP 1 Score: 88.9669 bits (219), Expect = 2.494e-19
Identity = 59/166 (35.54%), Postives = 89/166 (53.61%), Query Frame = 1 
Query:   49 EQIFNVDETGLYWKRMPERTYIHKEEKSMPGFKAFKDRITVLLGGNIVGY-KLKPFVVHRSKNPRAFKGVKRNMLPVNYNSNKSAWMTQLLFEDWFMNVFATEVKEYCNQHKIPFRILLLLDNAXXXXXXXXXXXXNIQIMYLPPNTTSILQPMDQGAIATFKAHY 543
            E I   +ETGL +K +P +T+  K+EK   G K+ K+RIT+L G +  G  KL P V+ +S  PR  K +  + L   Y SN+  WMT+ +F +    +     K +  +++   +ILL +DN       L     N+++ +   N TS LQPMD+G IA FK  Y
Sbjct: 2170 EDIDKAEETGLLYKCLPNKTFNIKDEKCFNGEKS-KERITILFGCDAAGSDKLTPLVIGKSLKPRCIKLINMSNLGFYYLSNRKTWMTEGVFRESIAKI----DKRFLAKNR---KILLFIDN--FSGHALKSQSNNVKVAFFHLNCTSKLQPMDKGIIANFKLKY 2325
[Close]
BLAST of HTH CENPB-type domain-containing protein vs. Planmine SMEST
Match: SMESG000029226.1 (SMESG000029226.1)

HSP 1 Score: 88.9669 bits (219), Expect = 2.598e-19
Identity = 59/166 (35.54%), Postives = 89/166 (53.61%), Query Frame = 1 
Query:   49 EQIFNVDETGLYWKRMPERTYIHKEEKSMPGFKAFKDRITVLLGGNIVGY-KLKPFVVHRSKNPRAFKGVKRNMLPVNYNSNKSAWMTQLLFEDWFMNVFATEVKEYCNQHKIPFRILLLLDNAXXXXXXXXXXXXNIQIMYLPPNTTSILQPMDQGAIATFKAHY 543
            E I   +ETGL +K +P +T+  K+EK   G K+ K+RIT+L G +  G  KL P V+ +S  PR  K +  + L   Y SN+  WMT+ +F +    +     K +  +++   +ILL +DN       L     N+++ +   N TS LQPMD+G IA FK  Y
Sbjct: 2263 EDIDKAEETGLLYKCLPNKTFNIKDEKCFNGEKS-KERITILFGCDAAGSDKLTPLVIGKSLKPRCIKLINMSNLGFYYLSNRKTWMTEGVFRESIAKI----DKRFLAKNR---KILLFIDN--FSGHALKSQSNNVKVAFFHLNCTSKLQPMDKGIIANFKLKY 2418
The following BLAST results are available for this feature:
BLAST of HTH CENPB-type domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
TIGD13.623e-6754.89tigger transposable element derived 1 [Source:HGNC... [more]
JRKL2.268e-4242.39JRK like [Source:HGNC Symbol;Acc:HGNC:6200][more]
TIGD22.912e-3739.13tigger transposable element derived 2 [Source:HGNC... [more]
TIGD22.912e-3739.13tigger transposable element derived 2 [Source:HGNC... [more]
JRK3.574e-3234.92Jrk helix-turn-helix protein [Source:HGNC Symbol;A... [more]
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BLAST of HTH CENPB-type domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of HTH CENPB-type domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of HTH CENPB-type domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of HTH CENPB-type domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 3
Match NameE-valueIdentityDescription
kif61.931e-3232.06kinesin family member 6 [Source:Xenbase;Acc:XB-GEN... [more]
apmapl2.223e-1633.33adipocyte plasma membrane associated protein LIKE ... [more]
ENSXETT00000046714.11.655e-1541.73pep primary_assembly:Xenopus_tropicalis_v9.1:KV460... [more]
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BLAST of HTH CENPB-type domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Jrkl1.865e-4041.05Jrk-like [Source:MGI Symbol;Acc:MGI:1924782][more]
Tigd25.850e-3636.84tigger transposable element derived 2 [Source:MGI ... [more]
Jrk1.780e-3033.33jerky [Source:MGI Symbol;Acc:MGI:106214][more]
Tigd42.082e-2032.75tigger transposable element derived 4 [Source:MGI ... [more]
Tigd51.210e-1632.33tigger transposable element derived 5 [Source:MGI ... [more]
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BLAST of HTH CENPB-type domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q96MW7|TIGD1_HUMAN1.556e-6654.89Tigger transposable element-derived protein 1 OS=H... [more]
sp|Q9Y4A0|JERKL_HUMAN9.743e-4242.39Jerky protein homolog-like OS=Homo sapiens OX=9606... [more]
sp|B2RRL2|JERKL_MOUSE1.103e-3941.05Jerky protein homolog-like OS=Mus musculus OX=1009... [more]
sp|Q4W5G0|TIGD2_HUMAN1.251e-3639.13Tigger transposable element-derived protein 2 OS=H... [more]
sp|Q0VBL1|TIGD2_MOUSE3.462e-3536.84Tigger transposable element-derived protein 2 OS=M... [more]
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BLAST of HTH CENPB-type domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
K7GFF73.123e-8362.50HTH CENPB-type domain-containing protein OS=Pelodi... [more]
K7GC453.411e-8163.59Uncharacterized protein OS=Pelodiscus sinensis OX=... [more]
A0A452GZM61.715e-7963.13HTH CENPB-type domain-containing protein OS=Gopher... [more]
A0A452GH562.991e-7659.78HTH CENPB-type domain-containing protein OS=Gopher... [more]
M7BBU33.202e-7660.34Uncharacterized protein (Fragment) OS=Chelonia myd... [more]
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BLAST of HTH CENPB-type domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of HTH CENPB-type domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSPMAT00000004972.14.267e-5855.68pep scaffold:Pmarinus_7.0:GL476545:74372:75575:-1 ... [more]
ENSPMAT00000005921.15.399e-4557.55pep scaffold:Pmarinus_7.0:GL487978:976:2666:1 gene... [more]
ENSPMAT00000003106.11.293e-4149.53pep scaffold:Pmarinus_7.0:GL476998:37517:41189:1 g... [more]
ENSPMAT00000005656.11.315e-4047.86pep scaffold:Pmarinus_7.0:GL476578:539135:542172:1... [more]
ENSPMAT00000003283.11.163e-3849.65pep scaffold:Pmarinus_7.0:GL479064:1419:3178:1 gen... [more]
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BLAST of HTH CENPB-type domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of HTH CENPB-type domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 2
Match NameE-valueIdentityDescription
EDO447387.670e-1731.58Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO400009.842e-1433.33Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of HTH CENPB-type domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 3
Match NameE-valueIdentityDescription
ENSORLT00000031980.15.744e-5651.09pep primary_assembly:ASM223467v1:3:6881985:6888319... [more]
ENSORLT00000036785.15.675e-4342.16pep primary_assembly:ASM223467v1:22:11796267:11802... [more]
ENSORLT00000034610.13.952e-646.38pep primary_assembly:ASM223467v1:22:20217020:20217... [more]
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BLAST of HTH CENPB-type domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000027161.11.098e-2035.71SMESG000027161.1[more]
SMESG000029226.12.329e-1935.54SMESG000029226.1[more]
SMESG000029226.12.419e-1935.54SMESG000029226.1[more]
SMESG000029226.12.494e-1935.54SMESG000029226.1[more]
SMESG000029226.12.598e-1935.54SMESG000029226.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30017976 ID=SMED30017976|Name=HTH CENPB-type domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=934bp
TTTGTTGTTAAATTCAACGAGTTTTTAGAAGAAAACAATTATACAAAAGA
ACAAATATTTAATGTGGACGAGACCGGTCTGTATTGGAAGAGGATGCCTG
AACGTACGTATATTCATAAGGAGGAAAAAAGTATGCCAGGGTTTAAGGCT
TTTAAGGACCGTATAACAGTTTTATTAGGCGGAAATATTGTTGGTTATAA
ATTGAAACCTTTTGTTGTACATCGCTCGAAAAATCCAAGAGCATTTAAAG
GAGTAAAACGTAATATGTTACCCGTGAATTACAACTCTAATAAAAGTGCT
TGGATGACACAATTACTTTTTGAAGACTGGTTTATGAACGTATTTGCAAC
TGAAGTAAAAGAATATTGTAATCAGCATAAAATTCCATTTAGAATACTTT
TGCTACTTGATAATGCTCCTGGACATCCGCCACACCTAGGCGACTTACAC
CCGAACATCCAAATTATGTATCTGCCTCCGAATACTACGAGCATTTTGCA
GCCCATGGATCAGGGTGCTATAGCTACATTTAAGGCCCATTATTTAATAA
ATTACATTCACTCAAGCAATTATGGCTATTGAAGAGGGGATTACTTTAAA
AGAATTTTGGTCGAAGTTTAATATTCTTCAAGGAATTATAAATTTAGCAA
GCGGATGGAAAGAAGTCAAGGCTTCTTGTATGAGCGGAATATGGAAAAAA
CTAACAAAAATATTTGAAGAATCTAGAAGTTCGTCGATCGAAAAAGAAGT
TGACGTTGAGGAAATTACGGATCAGATTGTAGATCTTGGTTGGCAGCTCA
ATCTTGAAGTTGACAGTGAAGATATTAACCAACTTATTGCACACCAATTG
GATGACCTAGCGAATGAAGATTTATTGGAATTTGAAGCACAATGTGTTGG
AGAAAACGTTGATAAAGGCAAATCGGATGAAGAA
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protein sequence of SMED30017976-orf-1

>SMED30017976-orf-1 ID=SMED30017976-orf-1|Name=SMED30017976-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=121bp
MAIEEGITLKEFWSKFNILQGIINLASGWKEVKASCMSGIWKKLTKIFEE
SRSSSIEKEVDVEEITDQIVDLGWQLNLEVDSEDINQLIAHQLDDLANED
LLEFEAQCVGENVDKGKSDEE
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protein sequence of SMED30017976-orf-2

>SMED30017976-orf-2 ID=SMED30017976-orf-2|Name=SMED30017976-orf-2|organism=Schmidtea mediterranea sexual|type=polypeptide|length=194bp
FVVKFNEFLEENNYTKEQIFNVDETGLYWKRMPERTYIHKEEKSMPGFKA
FKDRITVLLGGNIVGYKLKPFVVHRSKNPRAFKGVKRNMLPVNYNSNKSA
WMTQLLFEDWFMNVFATEVKEYCNQHKIPFRILLLLDNAPGHPPHLGDLH
PNIQIMYLPPNTTSILQPMDQGAIATFKAHYLINYIHSSNYGY*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000099neuron
Vocabulary: INTERPRO
TermDefinition
IPR004875DDE_SF_endonuclease_dom
Vocabulary: molecular function
TermDefinition
GO:0003676nucleic acid binding
GO:0003677DNA binding