PRKCA-binding protein

Overview
NamePRKCA-binding protein
Smed IDSMED30017874
Length (bp)1442
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of PRKCA-binding protein (SMED30017874) t-SNE clustered cells

Violin plots show distribution of expression levels for PRKCA-binding protein (SMED30017874) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of PRKCA-binding protein (SMED30017874) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for PRKCA-binding protein (SMED30017874) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30017874

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 3

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
pharynxSMED30017874SMESG000013976.1 dd_Smed_v4_11769_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30017874SMESG000013976.1 dd_Smed_v4_11769_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30017874SMESG000013976.1 dd_Smed_v4_11769_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of PRKCA-binding protein vs. Ensembl Human
Match: PICK1 (protein interacting with PRKCA 1 [Source:HGNC Symbol;Acc:HGNC:9394])

HSP 1 Score: 187.963 bits (476), Expect = 1.819e-95
Identity = 112/216 (51.85%), Postives = 151/216 (69.91%), Query Frame = 1 
Query:  127 QEDKCGMRVTSGSVVLNKDKHSLXXXXXXXXXXXXXXXXXVQIFDNTVAAKDGTLEAGDEVTAIDKKSVKGVSRGEVAKWIQKAENKVTIYYNKLHLDKNQGKSVEMIFKRFKHRLVENIDSSTADFLGLSRAILVNDSLMKRLELLNQTSHLFEDLS----NFISKFNEESKESAIIHKKMAEVFENIGVKEPQANASEAFLIFAKGQRCMQKYS 762
            +EDK G+    G V L KD  +LIGISIGGG  YCPC+YIVQ+FDNT AA DGT+ AGDE+T ++ +S+KG ++ EVAK IQ+ + +VTI+YNKL  D  QG S++++ K+ KHRLVEN+ S TAD LGLSRAIL ND L+KRLE L +T+ L++ ++    N +  F E S+     H+   +VF  IGV+EPQ  ASEAF+ FA   R ++K+ 
Sbjct:   10 EEDKLGIPTVPGKVTLQKDAQNLIGISIGGGAQYCPCLYIVQVFDNTPAALDGTVAAGDEITGVNGRSIKGKTKVEVAKMIQEVKGEVTIHYNKLQADPKQGMSLDIVLKKVKHRLVENMSSGTADALGLSRAILCNDGLVKRLEELERTAELYKGMTEHTKNLLRAFYELSQ----THRAFGDVFSVIGVREPQPAASEAFVKFADAHRSIEKFG 221

HSP 2 Score: 182.57 bits (462), Expect = 1.819e-95
Identity = 83/127 (65.35%), Postives = 102/127 (80.31%), Query Frame = 3 
Query:  819 VIPDTKLTIKKYLEAKFEYLSYCLKVKEMDDEELCYVALHEALYRIETGNYEYRLLLRCRQNSRKKFSKMRNDVLEKMELLDNKHVQDIVKNLGKFMDILKQYYNDNYSAWKNAQIFPIEIDISSLT 1199
             IPDT+LTIKKYL+ KFEYLSYCLKVKEMDDEE   +AL E LYR+ TGNYEYRL+LRCRQ +R +FS+MR DVLEKMELLD KHVQDIV  L + +  + +YYND Y+  ++A +FPIE+D++  T
Sbjct:  242 AIPDTRLTIKKYLDVKFEYLSYCLKVKEMDDEEYSCIALGEPLYRVSTGNYEYRLILRCRQEARARFSQMRKDVLEKMELLDQKHVQDIVFQLQRLVSTMSKYYNDCYAVLRDADVFPIEVDLAHTT 368
[Close]
BLAST of PRKCA-binding protein vs. Ensembl Human
Match: PICK1 (protein interacting with PRKCA 1 [Source:HGNC Symbol;Acc:HGNC:9394])

HSP 1 Score: 187.963 bits (476), Expect = 1.819e-95
Identity = 112/216 (51.85%), Postives = 151/216 (69.91%), Query Frame = 1 
Query:  127 QEDKCGMRVTSGSVVLNKDKHSLXXXXXXXXXXXXXXXXXVQIFDNTVAAKDGTLEAGDEVTAIDKKSVKGVSRGEVAKWIQKAENKVTIYYNKLHLDKNQGKSVEMIFKRFKHRLVENIDSSTADFLGLSRAILVNDSLMKRLELLNQTSHLFEDLS----NFISKFNEESKESAIIHKKMAEVFENIGVKEPQANASEAFLIFAKGQRCMQKYS 762
            +EDK G+    G V L KD  +LIGISIGGG  YCPC+YIVQ+FDNT AA DGT+ AGDE+T ++ +S+KG ++ EVAK IQ+ + +VTI+YNKL  D  QG S++++ K+ KHRLVEN+ S TAD LGLSRAIL ND L+KRLE L +T+ L++ ++    N +  F E S+     H+   +VF  IGV+EPQ  ASEAF+ FA   R ++K+ 
Sbjct:   10 EEDKLGIPTVPGKVTLQKDAQNLIGISIGGGAQYCPCLYIVQVFDNTPAALDGTVAAGDEITGVNGRSIKGKTKVEVAKMIQEVKGEVTIHYNKLQADPKQGMSLDIVLKKVKHRLVENMSSGTADALGLSRAILCNDGLVKRLEELERTAELYKGMTEHTKNLLRAFYELSQ----THRAFGDVFSVIGVREPQPAASEAFVKFADAHRSIEKFG 221

HSP 2 Score: 182.57 bits (462), Expect = 1.819e-95
Identity = 83/127 (65.35%), Postives = 102/127 (80.31%), Query Frame = 3 
Query:  819 VIPDTKLTIKKYLEAKFEYLSYCLKVKEMDDEELCYVALHEALYRIETGNYEYRLLLRCRQNSRKKFSKMRNDVLEKMELLDNKHVQDIVKNLGKFMDILKQYYNDNYSAWKNAQIFPIEIDISSLT 1199
             IPDT+LTIKKYL+ KFEYLSYCLKVKEMDDEE   +AL E LYR+ TGNYEYRL+LRCRQ +R +FS+MR DVLEKMELLD KHVQDIV  L + +  + +YYND Y+  ++A +FPIE+D++  T
Sbjct:  242 AIPDTRLTIKKYLDVKFEYLSYCLKVKEMDDEEYSCIALGEPLYRVSTGNYEYRLILRCRQEARARFSQMRKDVLEKMELLDQKHVQDIVFQLQRLVSTMSKYYNDCYAVLRDADVFPIEVDLAHTT 368
[Close]
BLAST of PRKCA-binding protein vs. Ensembl Human
Match: PICK1 (protein interacting with PRKCA 1 [Source:HGNC Symbol;Acc:HGNC:9394])

HSP 1 Score: 188.734 bits (478), Expect = 1.626e-56
Identity = 112/216 (51.85%), Postives = 151/216 (69.91%), Query Frame = 1 
Query:  127 QEDKCGMRVTSGSVVLNKDKHSLXXXXXXXXXXXXXXXXXVQIFDNTVAAKDGTLEAGDEVTAIDKKSVKGVSRGEVAKWIQKAENKVTIYYNKLHLDKNQGKSVEMIFKRFKHRLVENIDSSTADFLGLSRAILVNDSLMKRLELLNQTSHLFEDLS----NFISKFNEESKESAIIHKKMAEVFENIGVKEPQANASEAFLIFAKGQRCMQKYS 762
            +EDK G+    G V L KD  +LIGISIGGG  YCPC+YIVQ+FDNT AA DGT+ AGDE+T ++ +S+KG ++ EVAK IQ+ + +VTI+YNKL  D  QG S++++ K+ KHRLVEN+ S TAD LGLSRAIL ND L+KRLE L +T+ L++ ++    N +  F E S+     H+   +VF  IGV+EPQ  ASEAF+ FA   R ++K+ 
Sbjct:   10 EEDKLGIPTVPGKVTLQKDAQNLIGISIGGGAQYCPCLYIVQVFDNTPAALDGTVAAGDEITGVNGRSIKGKTKVEVAKMIQEVKGEVTIHYNKLQADPKQGMSLDIVLKKVKHRLVENMSSGTADALGLSRAILCNDGLVKRLEELERTAELYKGMTEHTKNLLRAFYELSQ----THRAFGDVFSVIGVREPQPAASEAFVKFADAHRSIEKFG 221
[Close]
BLAST of PRKCA-binding protein vs. Ensembl Human
Match: PICK1 (protein interacting with PRKCA 1 [Source:HGNC Symbol;Acc:HGNC:9394])

HSP 1 Score: 116.316 bits (290), Expect = 1.913e-30
Identity = 71/125 (56.80%), Postives = 94/125 (75.20%), Query Frame = 1 
Query:  127 QEDKCGMRVTSGSVVLNKDKHSLXXXXXXXXXXXXXXXXXVQIFDNTVAAKDGTLEAGDEVTAIDKKSVKGVSRGEVAKWIQKAENKVTIYYNKLHLDKNQGKSVEMIFKRFKHRLVENIDSSTA 501
            +EDK G+    G V L KD  +LIGISIGGG  YCPC+YIVQ+FDNT AA DGT+ AGDE+T ++ +S+KG ++ EVAK IQ+ + +VTI+YNKL  D  QG S++++ K+ KHRLVEN+ S TA
Sbjct:   10 EEDKLGIPTVPGKVTLQKDAQNLIGISIGGGAQYCPCLYIVQVFDNTPAALDGTVAAGDEITGVNGRSIKGKTKVEVAKMIQEVKGEVTIHYNKLQADPKQGMSLDIVLKKVKHRLVENMSSGTA 134
[Close]
BLAST of PRKCA-binding protein vs. Ensembl Human
Match: PICK1 (protein interacting with PRKCA 1 [Source:HGNC Symbol;Acc:HGNC:9394])

HSP 1 Score: 91.6633 bits (226), Expect = 1.338e-21
Identity = 60/107 (56.07%), Postives = 80/107 (74.77%), Query Frame = 1 
Query:  127 QEDKCGMRVTSGSVVLNKDKHSLXXXXXXXXXXXXXXXXXVQIFDNTVAAKDGTLEAGDEVTAIDKKSVKGVSRGEVAKWIQKAENKVTIYYNKLHLDKNQGKSVEM 447
            +EDK G+    G V L KD  +LIGISIGGG  YCPC+YIVQ+FDNT AA DGT+ AGDE+T ++ +S+KG ++ EVAK IQ+ + +VTI+YNKL  D  QG S+++
Sbjct:   10 EEDKLGIPTVPGKVTLQKDAQNLIGISIGGGAQYCPCLYIVQVFDNTPAALDGTVAAGDEITGVNGRSIKGKTKVEVAKMIQEVKGEVTIHYNKLQADPKQGMSLDI 116
[Close]
BLAST of PRKCA-binding protein vs. Ensembl Celegans
Match: Y57G11C.22 (pep chromosome:WBcel235:IV:14837112:14853662:1 gene:WBGene00013317.1 transcript:Y57G11C.22a.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:Y57G11C.22)

HSP 1 Score: 153.295 bits (386), Expect = 4.575e-68
Identity = 72/126 (57.14%), Postives = 94/126 (74.60%), Query Frame = 3 
Query:  819 VIPDTKLTIKKYLEAKFEYLSYCLKVKEMDDEELCYVALHEALYRIETGNYEYRLLLRCRQNSRKKFSKMRNDVLEKMELLDNKHVQDIVKNLGKFMDILKQYYNDNYSAWKNAQIFPIEIDISSL 1196
            V+PDT+LTIKKYL+ K+EYLSYCLK+KEMDDEE+ +VA+ E LYR+ETGNYEYR++LRCRQ  R +F KMR+DV+ K+ELLD KHV+DI ++L  F   + +   +     K     PIEID+  L
Sbjct:  238 VVPDTRLTIKKYLDVKYEYLSYCLKLKEMDDEEVEFVAIQEPLYRVETGNYEYRVMLRCRQECRARFMKMRDDVMVKIELLDQKHVRDIAQHLAIFAKTMAKCQQECAEILKERIDVPIEIDLEQL 363

HSP 2 Score: 124.79 bits (312), Expect = 4.575e-68
Identity = 82/210 (39.05%), Postives = 130/210 (61.90%), Query Frame = 1 
Query:  127 QEDKCGMRVTSGSVVLNKDKHSLXXXXXXXXXXXXXXXXXVQIFDNTVAAKDGTLEAGDEVTAIDKKSVKGVSRGEVAKWIQKAENKVTIYYNKLHLDKNQGKSVEMIFKRFKHRLVENIDSSTADFLGLSRAILVNDSLMKRLELLNQTSHLFEDLSNFISKFNEESKESAIIHKKMAEVFENIGVKEPQANASEAFLIFAKGQRCMQK 756
            +ED+ GMR+ S ++ L KD+  ++GISIGGG PYCPC+Y+VQ+FD + A KDG +  GDE+ AI+  +VKG  +  VA+ IQ + N V I  NKL     +GK+++++ K+ KH++VE +D  +AD LGLSRAIL ND L ++ ++L + +  +  L  +     +  ++ +   K+   +F ++   E Q  A+EAF  F    R + K
Sbjct:    6 EEDRLGMRIQSETIELTKDEKGVVGISIGGGGPYCPCVYVVQVFDKSPAFKDGRIRCGDEIVAINGITVKGERKSAVAQLIQVSLNPVKITINKLEEANTKGKTLDILIKKVKHKVVEFVDQDSADALGLSRAILTNDPLAEKEKILEENAEFYRHLVAYFGDMFQYQQKISECQKEFGSIFCDLAAHEKQQTANEAFSSFGDKHRMIAK 215
[Close]
BLAST of PRKCA-binding protein vs. Ensembl Fly
Match: PICK1 (gene:FBgn0032447 transcript:FBtr0080395)

HSP 1 Score: 176.792 bits (447), Expect = 6.888e-83
Identity = 107/212 (50.47%), Postives = 149/212 (70.28%), Query Frame = 1 
Query:  121 FPQEDKCGMRVTSGSVVLNKDKHSLXXXXXXXXXXXXXXXXXVQIFDNTVAAKDGTLEAGDEVTAIDKKSVKGVSRGEVAKWIQKAENKVTIYYNKLHLDKNQGKSVEMIFKRFKHRLVENIDSSTADFLGLSRAILVNDSLMKRLELLNQTSHLFEDLSNFISKFNEESKESAIIHKKMAEVFENIGVKEPQANASEAFLIFAKGQRCMQK 756
            F +EDK GM V++ +VV+ KD+ +LIGISIGGG P CPC+YIVQIFD T AA++G+L++GDE+ A++  SVKG ++ EVAK IQ A ++V I+YNKLH D  QGK++++I K+ KHR+V+N+ S+TAD LGLSRAIL NDSL+KRLE L  T  +++ L     +  +   +    +K   + F  I V EPQ  ASEAF  F +  R ++K
Sbjct:   10 FFEEDKMGMTVSTNAVVITKDQSNLIGISIGGGAPMCPCLYIVQIFDGTPAAREGSLQSGDELLAVNSVSVKGKTKVEVAKMIQTATDEVVIHYNKLHADPEQGKTLDIILKKLKHRIVDNLSSNTADTLGLSRAILCNDSLVKRLEELEGTELMYKGLVEHARRMLKAYYDLLQTYKSFGDCFTQISVHEPQQRASEAFRTFGEFHRTLEK 221

HSP 2 Score: 151.369 bits (381), Expect = 6.888e-83
Identity = 71/123 (57.72%), Postives = 91/123 (73.98%), Query Frame = 3 
Query:  819 VIPDTKLTIKKYLEAKFEYLSYCLKVKEMDDEELCYVALHEALYRIETGNYEYRLLLRCRQNSRKKFSKMRNDVLEKMELLDNKHVQDIVKNLGKFMDILKQYYNDNYSAWKN-AQIFPIEID 1184
             IPDTKLT+++Y +AKF YLSYCLKVKEMDDEE  + AL E LYR+ETGNYEYRL+LRCRQ++R KF+K+R DVLEKMELL+ KH  D+ K L   ++ L + +        +   +FPIE+D
Sbjct:  244 AIPDTKLTVRRYADAKFTYLSYCLKVKEMDDEEHGFAALQEPLYRVETGNYEYRLILRCRQDARSKFAKLRTDVLEKMELLECKHAMDLNKQLRSLLESLAELHRSLVDRLDSLPPLFPIEVD 366
[Close]
BLAST of PRKCA-binding protein vs. Ensembl Fly
Match: PICK1 (gene:FBgn0032447 transcript:FBtr0340543)

HSP 1 Score: 173.326 bits (438), Expect = 5.532e-82
Identity = 104/208 (50.00%), Postives = 146/208 (70.19%), Query Frame = 1 
Query:  133 DKCGMRVTSGSVVLNKDKHSLXXXXXXXXXXXXXXXXXVQIFDNTVAAKDGTLEAGDEVTAIDKKSVKGVSRGEVAKWIQKAENKVTIYYNKLHLDKNQGKSVEMIFKRFKHRLVENIDSSTADFLGLSRAILVNDSLMKRLELLNQTSHLFEDLSNFISKFNEESKESAIIHKKMAEVFENIGVKEPQANASEAFLIFAKGQRCMQK 756
            D+ GM V++ +VV+ KD+ +LIGISIGGG P CPC+YIVQIFD T AA++G+L++GDE+ A++  SVKG ++ EVAK IQ A ++V I+YNKLH D  QGK++++I K+ KHR+V+N+ S+TAD LGLSRAIL NDSL+KRLE L  T  +++ L     +  +   +    +K   + F  I V EPQ  ASEAF  F +  R ++K
Sbjct:   87 DRLGMTVSTNAVVITKDQSNLIGISIGGGAPMCPCLYIVQIFDGTPAAREGSLQSGDELLAVNSVSVKGKTKVEVAKMIQTATDEVVIHYNKLHADPEQGKTLDIILKKLKHRIVDNLSSNTADTLGLSRAILCNDSLVKRLEELEGTELMYKGLVEHARRMLKAYYDLLQTYKSFGDCFTQISVHEPQQRASEAFRTFGEFHRTLEK 294

HSP 2 Score: 151.754 bits (382), Expect = 5.532e-82
Identity = 71/123 (57.72%), Postives = 91/123 (73.98%), Query Frame = 3 
Query:  819 VIPDTKLTIKKYLEAKFEYLSYCLKVKEMDDEELCYVALHEALYRIETGNYEYRLLLRCRQNSRKKFSKMRNDVLEKMELLDNKHVQDIVKNLGKFMDILKQYYNDNYSAWKN-AQIFPIEID 1184
             IPDTKLT+++Y +AKF YLSYCLKVKEMDDEE  + AL E LYR+ETGNYEYRL+LRCRQ++R KF+K+R DVLEKMELL+ KH  D+ K L   ++ L + +        +   +FPIE+D
Sbjct:  317 AIPDTKLTVRRYADAKFTYLSYCLKVKEMDDEEHGFAALQEPLYRVETGNYEYRLILRCRQDARSKFAKLRTDVLEKMELLECKHAMDLNKQLRSLLESLAELHRSLVDRLDSLPPLFPIEVD 439
[Close]
BLAST of PRKCA-binding protein vs. Ensembl Fly
Match: PICK1 (gene:FBgn0032447 transcript:FBtr0340542)

HSP 1 Score: 167.933 bits (424), Expect = 2.858e-80
Identity = 102/204 (50.00%), Postives = 143/204 (70.10%), Query Frame = 1 
Query:  145 MRVTSGSVVLNKDKHSLXXXXXXXXXXXXXXXXXVQIFDNTVAAKDGTLEAGDEVTAIDKKSVKGVSRGEVAKWIQKAENKVTIYYNKLHLDKNQGKSVEMIFKRFKHRLVENIDSSTADFLGLSRAILVNDSLMKRLELLNQTSHLFEDLSNFISKFNEESKESAIIHKKMAEVFENIGVKEPQANASEAFLIFAKGQRCMQK 756
            M V++ +VV+ KD+ +LIGISIGGG P CPC+YIVQIFD T AA++G+L++GDE+ A++  SVKG ++ EVAK IQ A ++V I+YNKLH D  QGK++++I K+ KHR+V+N+ S+TAD LGLSRAIL NDSL+KRLE L  T  +++ L     +  +   +    +K   + F  I V EPQ  ASEAF  F +  R ++K
Sbjct:    1 MTVSTNAVVITKDQSNLIGISIGGGAPMCPCLYIVQIFDGTPAAREGSLQSGDELLAVNSVSVKGKTKVEVAKMIQTATDEVVIHYNKLHADPEQGKTLDIILKKLKHRIVDNLSSNTADTLGLSRAILCNDSLVKRLEELEGTELMYKGLVEHARRMLKAYYDLLQTYKSFGDCFTQISVHEPQQRASEAFRTFGEFHRTLEK 204

HSP 2 Score: 151.369 bits (381), Expect = 2.858e-80
Identity = 71/123 (57.72%), Postives = 91/123 (73.98%), Query Frame = 3 
Query:  819 VIPDTKLTIKKYLEAKFEYLSYCLKVKEMDDEELCYVALHEALYRIETGNYEYRLLLRCRQNSRKKFSKMRNDVLEKMELLDNKHVQDIVKNLGKFMDILKQYYNDNYSAWKN-AQIFPIEID 1184
             IPDTKLT+++Y +AKF YLSYCLKVKEMDDEE  + AL E LYR+ETGNYEYRL+LRCRQ++R KF+K+R DVLEKMELL+ KH  D+ K L   ++ L + +        +   +FPIE+D
Sbjct:  227 AIPDTKLTVRRYADAKFTYLSYCLKVKEMDDEEHGFAALQEPLYRVETGNYEYRLILRCRQDARSKFAKLRTDVLEKMELLECKHAMDLNKQLRSLLESLAELHRSLVDRLDSLPPLFPIEVD 349
[Close]
BLAST of PRKCA-binding protein vs. Ensembl Fly
Match: PICK1 (gene:FBgn0032447 transcript:FBtr0340544)

HSP 1 Score: 167.933 bits (424), Expect = 2.858e-80
Identity = 102/204 (50.00%), Postives = 143/204 (70.10%), Query Frame = 1 
Query:  145 MRVTSGSVVLNKDKHSLXXXXXXXXXXXXXXXXXVQIFDNTVAAKDGTLEAGDEVTAIDKKSVKGVSRGEVAKWIQKAENKVTIYYNKLHLDKNQGKSVEMIFKRFKHRLVENIDSSTADFLGLSRAILVNDSLMKRLELLNQTSHLFEDLSNFISKFNEESKESAIIHKKMAEVFENIGVKEPQANASEAFLIFAKGQRCMQK 756
            M V++ +VV+ KD+ +LIGISIGGG P CPC+YIVQIFD T AA++G+L++GDE+ A++  SVKG ++ EVAK IQ A ++V I+YNKLH D  QGK++++I K+ KHR+V+N+ S+TAD LGLSRAIL NDSL+KRLE L  T  +++ L     +  +   +    +K   + F  I V EPQ  ASEAF  F +  R ++K
Sbjct:    1 MTVSTNAVVITKDQSNLIGISIGGGAPMCPCLYIVQIFDGTPAAREGSLQSGDELLAVNSVSVKGKTKVEVAKMIQTATDEVVIHYNKLHADPEQGKTLDIILKKLKHRIVDNLSSNTADTLGLSRAILCNDSLVKRLEELEGTELMYKGLVEHARRMLKAYYDLLQTYKSFGDCFTQISVHEPQQRASEAFRTFGEFHRTLEK 204

HSP 2 Score: 151.369 bits (381), Expect = 2.858e-80
Identity = 71/123 (57.72%), Postives = 91/123 (73.98%), Query Frame = 3 
Query:  819 VIPDTKLTIKKYLEAKFEYLSYCLKVKEMDDEELCYVALHEALYRIETGNYEYRLLLRCRQNSRKKFSKMRNDVLEKMELLDNKHVQDIVKNLGKFMDILKQYYNDNYSAWKN-AQIFPIEID 1184
             IPDTKLT+++Y +AKF YLSYCLKVKEMDDEE  + AL E LYR+ETGNYEYRL+LRCRQ++R KF+K+R DVLEKMELL+ KH  D+ K L   ++ L + +        +   +FPIE+D
Sbjct:  227 AIPDTKLTVRRYADAKFTYLSYCLKVKEMDDEEHGFAALQEPLYRVETGNYEYRLILRCRQDARSKFAKLRTDVLEKMELLECKHAMDLNKQLRSLLESLAELHRSLVDRLDSLPPLFPIEVD 349
[Close]
BLAST of PRKCA-binding protein vs. Ensembl Fly
Match: PICK1 (gene:FBgn0032447 transcript:FBtr0080396)

HSP 1 Score: 167.933 bits (424), Expect = 2.858e-80
Identity = 102/204 (50.00%), Postives = 143/204 (70.10%), Query Frame = 1 
Query:  145 MRVTSGSVVLNKDKHSLXXXXXXXXXXXXXXXXXVQIFDNTVAAKDGTLEAGDEVTAIDKKSVKGVSRGEVAKWIQKAENKVTIYYNKLHLDKNQGKSVEMIFKRFKHRLVENIDSSTADFLGLSRAILVNDSLMKRLELLNQTSHLFEDLSNFISKFNEESKESAIIHKKMAEVFENIGVKEPQANASEAFLIFAKGQRCMQK 756
            M V++ +VV+ KD+ +LIGISIGGG P CPC+YIVQIFD T AA++G+L++GDE+ A++  SVKG ++ EVAK IQ A ++V I+YNKLH D  QGK++++I K+ KHR+V+N+ S+TAD LGLSRAIL NDSL+KRLE L  T  +++ L     +  +   +    +K   + F  I V EPQ  ASEAF  F +  R ++K
Sbjct:    1 MTVSTNAVVITKDQSNLIGISIGGGAPMCPCLYIVQIFDGTPAAREGSLQSGDELLAVNSVSVKGKTKVEVAKMIQTATDEVVIHYNKLHADPEQGKTLDIILKKLKHRIVDNLSSNTADTLGLSRAILCNDSLVKRLEELEGTELMYKGLVEHARRMLKAYYDLLQTYKSFGDCFTQISVHEPQQRASEAFRTFGEFHRTLEK 204

HSP 2 Score: 151.369 bits (381), Expect = 2.858e-80
Identity = 71/123 (57.72%), Postives = 91/123 (73.98%), Query Frame = 3 
Query:  819 VIPDTKLTIKKYLEAKFEYLSYCLKVKEMDDEELCYVALHEALYRIETGNYEYRLLLRCRQNSRKKFSKMRNDVLEKMELLDNKHVQDIVKNLGKFMDILKQYYNDNYSAWKN-AQIFPIEID 1184
             IPDTKLT+++Y +AKF YLSYCLKVKEMDDEE  + AL E LYR+ETGNYEYRL+LRCRQ++R KF+K+R DVLEKMELL+ KH  D+ K L   ++ L + +        +   +FPIE+D
Sbjct:  227 AIPDTKLTVRRYADAKFTYLSYCLKVKEMDDEEHGFAALQEPLYRVETGNYEYRLILRCRQDARSKFAKLRTDVLEKMELLECKHAMDLNKQLRSLLESLAELHRSLVDRLDSLPPLFPIEVD 349
[Close]
BLAST of PRKCA-binding protein vs. Ensembl Zebrafish
Match: pick1 (protein interacting with prkca 1 [Source:ZFIN;Acc:ZDB-GENE-061013-283])

HSP 1 Score: 192.2 bits (487), Expect = 3.157e-96
Identity = 113/212 (53.30%), Postives = 147/212 (69.34%), Query Frame = 1 
Query:  127 QEDKCGMRVTSGSVVLNKDKHSLXXXXXXXXXXXXXXXXXVQIFDNTVAAKDGTLEAGDEVTAIDKKSVKGVSRGEVAKWIQKAENKVTIYYNKLHLDKNQGKSVEMIFKRFKHRLVENIDSSTADFLGLSRAILVNDSLMKRLELLNQTSHLFEDLSNFISKFNEESKESAIIHKKMAEVFENIGVKEPQANASEAFLIFAKGQRCMQKYS 762
            +EDK G+    G+V L KD  +LIGISIGGG  +CPC+YIVQ+FDNT AA DGTL AGDE+T ++ K VKG ++ EVAK IQ  + +V I YNKL  D  QGKS++++ K+ KHRLVEN+ S TAD LGLSRAIL ND L+KRLE L +T+ L++ L     +      E +  H+   +VF  IGV+EPQA ASEAF+ FA+  R M+K+ 
Sbjct:   10 EEDKLGIPTVPGTVTLKKDSQNLIGISIGGGAQFCPCLYIVQVFDNTAAALDGTLAAGDEITGVNGKPVKGKTKVEVAKMIQAVQGEVVIQYNKLQADPKQGKSLDIVLKKVKHRLVENMSSGTADALGLSRAILCNDGLVKRLEELEKTAELYKGLMEHTKRLLRAFYELSQTHRAFGDVFSVIGVREPQAAASEAFVKFAEAHRNMEKFG 221

HSP 2 Score: 180.644 bits (457), Expect = 3.157e-96
Identity = 85/130 (65.38%), Postives = 104/130 (80.00%), Query Frame = 3 
Query:  819 VIPDTKLTIKKYLEAKFEYLSYCLKVKEMDDEELCYVALHEALYRIETGNYEYRLLLRCRQNSRKKFSKMRNDVLEKMELLDNKHVQDIVKNLGKFMDILKQYYNDNYSAWKNAQIFPIEIDISSLTHIN 1208
             IPDTKLTI+KYL+ KFEYLSYCLKVKEMDDEE   +AL + LYR+ TGNYEYRL+LRCRQ +R +F+KMR DVLEK+ELLD KHVQDIV  L +F+  +  YY+D Y+  K+A +FPIE+D+S  T IN
Sbjct:  242 AIPDTKLTIRKYLDVKFEYLSYCLKVKEMDDEEYSCIALGDPLYRVSTGNYEYRLVLRCRQEARARFAKMRKDVLEKIELLDQKHVQDIVFQLQRFVSGMSHYYDDCYAVLKDADVFPIEVDLSR-TMIN 370
[Close]
BLAST of PRKCA-binding protein vs. Ensembl Xenopus
Match: pick1 (protein interacting with PRKCA 1 [Source:NCBI gene;Acc:734086])

HSP 1 Score: 186.808 bits (473), Expect = 1.673e-92
Identity = 111/221 (50.23%), Postives = 149/221 (67.42%), Query Frame = 1 
Query:  100 FEDIMNSFPQEDKCGMRVTSGSVVLNKDKHSLXXXXXXXXXXXXXXXXXVQIFDNTVAAKDGTLEAGDEVTAIDKKSVKGVSRGEVAKWIQKAENKVTIYYNKLHLDKNQGKSVEMIFKRFKHRLVENIDSSTADFLGLSRAILVNDSLMKRLELLNQTSHLFEDLSNFISKFNEESKESAIIHKKMAEVFENIGVKEPQANASEAFLIFAKGQRCMQKYS 762
            F D+   F +EDK G+    G+V L KD  ++IGISIGGG  +CPC+YIVQ+FDNT A+ DGT+ AGDE+T ++ KSVKG ++ EVAK IQ  + +VTI+YNKL  D  QGKS++++ K+ KHRLVEN+ S TAD LGLSRAIL ND L+KRLE L +T   +  +     +      E +  H+   +VF  IGV+EPQ  ASEAF+ FA   R ++K+ 
Sbjct:    2 FSDLDYDF-EEDKLGIPTVPGTVTLKKDSQNVIGISIGGGAQHCPCLYIVQVFDNTPASLDGTIAAGDEITGVNGKSVKGKTKVEVAKMIQNVKGEVTIHYNKLQADPKQGKSLDIVLKKVKHRLVENLSSGTADALGLSRAILCNDGLVKRLEELEKTGEFYRGMMEHTKRLLRSFFELSQTHRAFGDVFSVIGVREPQPAASEAFVKFADAHRSIEKFG 221

HSP 2 Score: 174.096 bits (440), Expect = 1.673e-92
Identity = 81/127 (63.78%), Postives = 98/127 (77.17%), Query Frame = 3 
Query:  819 VIPDTKLTIKKYLEAKFEYLSYCLKVKEMDDEELCYVALHEALYRIETGNYEYRLLLRCRQNSRKKFSKMRNDVLEKMELLDNKHVQDIVKNLGKFMDILKQYYNDNYSAWKNAQIFPIEIDISSLT 1199
             IPDTKLTI+KYL+ KFEYLSYCLKVKEMDDEE   +AL E LYR+ TGNYEYRL+LRCRQ +R +F+KMR DVLEK+ELLD KHV DIV  L +F+  + +Y +  Y   K A IFPIE+D++  T
Sbjct:  242 AIPDTKLTIRKYLDVKFEYLSYCLKVKEMDDEEYSSIALGEPLYRVGTGNYEYRLILRCRQEARARFAKMRKDVLEKIELLDQKHVHDIVFQLQRFVSAMSKYNDQCYEVLKEADIFPIEVDLAKTT 368
[Close]
BLAST of PRKCA-binding protein vs. Ensembl Xenopus
Match: pick1 (protein interacting with PRKCA 1 [Source:NCBI gene;Acc:734086])

HSP 1 Score: 179.874 bits (455), Expect = 1.858e-90
Identity = 105/207 (50.72%), Postives = 141/207 (68.12%), Query Frame = 1 
Query:  142 GMRVTSGSVVLNKDKHSLXXXXXXXXXXXXXXXXXVQIFDNTVAAKDGTLEAGDEVTAIDKKSVKGVSRGEVAKWIQKAENKVTIYYNKLHLDKNQGKSVEMIFKRFKHRLVENIDSSTADFLGLSRAILVNDSLMKRLELLNQTSHLFEDLSNFISKFNEESKESAIIHKKMAEVFENIGVKEPQANASEAFLIFAKGQRCMQKYS 762
            G+    G+V L KD  ++IGISIGGG  +CPC+YIVQ+FDNT A+ DGT+ AGDE+T ++ KSVKG ++ EVAK IQ  + +VTI+YNKL  D  QGKS++++ K+ KHRLVEN+ S TAD LGLSRAIL ND L+KRLE L +T   +  +     +      E +  H+   +VF  IGV+EPQ  ASEAF+ FA   R ++K+ 
Sbjct:   31 GIPTVPGTVTLKKDSQNVIGISIGGGAQHCPCLYIVQVFDNTPASLDGTIAAGDEITGVNGKSVKGKTKVEVAKMIQNVKGEVTIHYNKLQADPKQGKSLDIVLKKVKHRLVENLSSGTADALGLSRAILCNDGLVKRLEELEKTGEFYRGMMEHTKRLLRSFFELSQTHRAFGDVFSVIGVREPQPAASEAFVKFADAHRSIEKFG 237

HSP 2 Score: 174.096 bits (440), Expect = 1.858e-90
Identity = 81/127 (63.78%), Postives = 98/127 (77.17%), Query Frame = 3 
Query:  819 VIPDTKLTIKKYLEAKFEYLSYCLKVKEMDDEELCYVALHEALYRIETGNYEYRLLLRCRQNSRKKFSKMRNDVLEKMELLDNKHVQDIVKNLGKFMDILKQYYNDNYSAWKNAQIFPIEIDISSLT 1199
             IPDTKLTI+KYL+ KFEYLSYCLKVKEMDDEE   +AL E LYR+ TGNYEYRL+LRCRQ +R +F+KMR DVLEK+ELLD KHV DIV  L +F+  + +Y +  Y   K A IFPIE+D++  T
Sbjct:  258 AIPDTKLTIRKYLDVKFEYLSYCLKVKEMDDEEYSSIALGEPLYRVGTGNYEYRLILRCRQEARARFAKMRKDVLEKIELLDQKHVHDIVFQLQRFVSAMSKYNDQCYEVLKEADIFPIEVDLAKTT 384
[Close]
BLAST of PRKCA-binding protein vs. Ensembl Xenopus
Match: pick1 (protein interacting with PRKCA 1 [Source:NCBI gene;Acc:734086])

HSP 1 Score: 179.874 bits (455), Expect = 2.486e-90
Identity = 105/207 (50.72%), Postives = 141/207 (68.12%), Query Frame = 1 
Query:  142 GMRVTSGSVVLNKDKHSLXXXXXXXXXXXXXXXXXVQIFDNTVAAKDGTLEAGDEVTAIDKKSVKGVSRGEVAKWIQKAENKVTIYYNKLHLDKNQGKSVEMIFKRFKHRLVENIDSSTADFLGLSRAILVNDSLMKRLELLNQTSHLFEDLSNFISKFNEESKESAIIHKKMAEVFENIGVKEPQANASEAFLIFAKGQRCMQKYS 762
            G+    G+V L KD  ++IGISIGGG  +CPC+YIVQ+FDNT A+ DGT+ AGDE+T ++ KSVKG ++ EVAK IQ  + +VTI+YNKL  D  QGKS++++ K+ KHRLVEN+ S TAD LGLSRAIL ND L+KRLE L +T   +  +     +      E +  H+   +VF  IGV+EPQ  ASEAF+ FA   R ++K+ 
Sbjct:   12 GIPTVPGTVTLKKDSQNVIGISIGGGAQHCPCLYIVQVFDNTPASLDGTIAAGDEITGVNGKSVKGKTKVEVAKMIQNVKGEVTIHYNKLQADPKQGKSLDIVLKKVKHRLVENLSSGTADALGLSRAILCNDGLVKRLEELEKTGEFYRGMMEHTKRLLRSFFELSQTHRAFGDVFSVIGVREPQPAASEAFVKFADAHRSIEKFG 218

HSP 2 Score: 173.711 bits (439), Expect = 2.486e-90
Identity = 81/127 (63.78%), Postives = 98/127 (77.17%), Query Frame = 3 
Query:  819 VIPDTKLTIKKYLEAKFEYLSYCLKVKEMDDEELCYVALHEALYRIETGNYEYRLLLRCRQNSRKKFSKMRNDVLEKMELLDNKHVQDIVKNLGKFMDILKQYYNDNYSAWKNAQIFPIEIDISSLT 1199
             IPDTKLTI+KYL+ KFEYLSYCLKVKEMDDEE   +AL E LYR+ TGNYEYRL+LRCRQ +R +F+KMR DVLEK+ELLD KHV DIV  L +F+  + +Y +  Y   K A IFPIE+D++  T
Sbjct:  239 AIPDTKLTIRKYLDVKFEYLSYCLKVKEMDDEEYSSIALGEPLYRVGTGNYEYRLILRCRQEARARFAKMRKDVLEKIELLDQKHVHDIVFQLQRFVSAMSKYNDQCYEVLKEADIFPIEVDLAKTT 365
[Close]
BLAST of PRKCA-binding protein vs. Ensembl Xenopus
Match: pick1 (protein interacting with PRKCA 1 [Source:NCBI gene;Acc:734086])

HSP 1 Score: 180.259 bits (456), Expect = 1.220e-51
Identity = 105/207 (50.72%), Postives = 141/207 (68.12%), Query Frame = 1 
Query:  142 GMRVTSGSVVLNKDKHSLXXXXXXXXXXXXXXXXXVQIFDNTVAAKDGTLEAGDEVTAIDKKSVKGVSRGEVAKWIQKAENKVTIYYNKLHLDKNQGKSVEMIFKRFKHRLVENIDSSTADFLGLSRAILVNDSLMKRLELLNQTSHLFEDLSNFISKFNEESKESAIIHKKMAEVFENIGVKEPQANASEAFLIFAKGQRCMQKYS 762
            G+    G+V L KD  ++IGISIGGG  +CPC+YIVQ+FDNT A+ DGT+ AGDE+T ++ KSVKG ++ EVAK IQ  + +VTI+YNKL  D  QGKS++++ K+ KHRLVEN+ S TAD LGLSRAIL ND L+KRLE L +T   +  +     +      E +  H+   +VF  IGV+EPQ  ASEAF+ FA   R ++K+ 
Sbjct:    8 GIPTVPGTVTLKKDSQNVIGISIGGGAQHCPCLYIVQVFDNTPASLDGTIAAGDEITGVNGKSVKGKTKVEVAKMIQNVKGEVTIHYNKLQADPKQGKSLDIVLKKVKHRLVENLSSGTADALGLSRAILCNDGLVKRLEELEKTGEFYRGMMEHTKRLLRSFFELSQTHRAFGDVFSVIGVREPQPAASEAFVKFADAHRSIEKFG 214

HSP 2 Score: 114.775 bits (286), Expect = 1.441e-27
Identity = 52/90 (57.78%), Postives = 66/90 (73.33%), Query Frame = 3 
Query:  930 ALHEALYRIETGNYEYRLLLRCRQNSRKKFSKMRNDVLEKMELLDNKHVQDIVKNLGKFMDILKQYYNDNYSAWKNAQIFPIEIDISSLT 1199
            AL E LYR+ TGNYEYRL+LRCRQ +R +F+KMR DVLEK+ELLD KHV DIV  L +F+  + +Y +  Y   K A IFPIE+D++  T
Sbjct:  241 ALGEPLYRVGTGNYEYRLILRCRQEARARFAKMRKDVLEKIELLDQKHVHDIVFQLQRFVSAMSKYNDQCYEVLKEADIFPIEVDLAKTT 330
[Close]
BLAST of PRKCA-binding protein vs. Ensembl Mouse
Match: Pick1 (protein interacting with C kinase 1 [Source:MGI Symbol;Acc:MGI:894645])

HSP 1 Score: 188.734 bits (478), Expect = 1.623e-96
Identity = 113/216 (52.31%), Postives = 151/216 (69.91%), Query Frame = 1 
Query:  127 QEDKCGMRVTSGSVVLNKDKHSLXXXXXXXXXXXXXXXXXVQIFDNTVAAKDGTLEAGDEVTAIDKKSVKGVSRGEVAKWIQKAENKVTIYYNKLHLDKNQGKSVEMIFKRFKHRLVENIDSSTADFLGLSRAILVNDSLMKRLELLNQTSHLFEDLS----NFISKFNEESKESAIIHKKMAEVFENIGVKEPQANASEAFLIFAKGQRCMQKYS 762
            +EDK G+    G V L KD  +LIGISIGGG  YCPC+YIVQ+FDNT AA DGT+ AGDE+T ++ KS+KG ++ EVAK IQ+ + +VTI+YNKL  D  QG S++++ K+ KHRLVEN+ S TAD LGLSRAIL ND L+KRLE L +T+ L++ ++    N +  F E S+     H+   +VF  IGV+EPQ  ASEAF+ FA   R ++K+ 
Sbjct:   10 EEDKLGIPTVPGKVTLQKDAQNLIGISIGGGAQYCPCLYIVQVFDNTPAALDGTVAAGDEITGVNGKSIKGKTKVEVAKMIQEVKGEVTIHYNKLQADPKQGMSLDIVLKKVKHRLVENMSSGTADALGLSRAILCNDGLVKRLEELERTAELYKGMTEHTKNLLRAFYELSQ----THRAFGDVFSVIGVREPQPAASEAFVKFADAHRSIEKFG 221

HSP 2 Score: 184.882 bits (468), Expect = 1.623e-96
Identity = 84/127 (66.14%), Postives = 103/127 (81.10%), Query Frame = 3 
Query:  819 VIPDTKLTIKKYLEAKFEYLSYCLKVKEMDDEELCYVALHEALYRIETGNYEYRLLLRCRQNSRKKFSKMRNDVLEKMELLDNKHVQDIVKNLGKFMDILKQYYNDNYSAWKNAQIFPIEIDISSLT 1199
             IPDT+LTIKKYL+ KFEYLSYCLKVKEMDDEE   +AL E LYR+ TGNYEYRL+LRCRQ +R +FS+MR DVLEKMELLD KHVQDIV  L +F+  + +YYND Y+  ++A +FPIE+D++  T
Sbjct:  242 AIPDTRLTIKKYLDVKFEYLSYCLKVKEMDDEEYSCIALGEPLYRVSTGNYEYRLILRCRQEARARFSQMRKDVLEKMELLDQKHVQDIVFQLQRFVSTMSKYYNDCYAVLQDADVFPIEVDLAHTT 368
[Close]
BLAST of PRKCA-binding protein vs. Ensembl Mouse
Match: Pick1 (protein interacting with C kinase 1 [Source:MGI Symbol;Acc:MGI:894645])

HSP 1 Score: 188.734 bits (478), Expect = 1.623e-96
Identity = 113/216 (52.31%), Postives = 151/216 (69.91%), Query Frame = 1 
Query:  127 QEDKCGMRVTSGSVVLNKDKHSLXXXXXXXXXXXXXXXXXVQIFDNTVAAKDGTLEAGDEVTAIDKKSVKGVSRGEVAKWIQKAENKVTIYYNKLHLDKNQGKSVEMIFKRFKHRLVENIDSSTADFLGLSRAILVNDSLMKRLELLNQTSHLFEDLS----NFISKFNEESKESAIIHKKMAEVFENIGVKEPQANASEAFLIFAKGQRCMQKYS 762
            +EDK G+    G V L KD  +LIGISIGGG  YCPC+YIVQ+FDNT AA DGT+ AGDE+T ++ KS+KG ++ EVAK IQ+ + +VTI+YNKL  D  QG S++++ K+ KHRLVEN+ S TAD LGLSRAIL ND L+KRLE L +T+ L++ ++    N +  F E S+     H+   +VF  IGV+EPQ  ASEAF+ FA   R ++K+ 
Sbjct:   10 EEDKLGIPTVPGKVTLQKDAQNLIGISIGGGAQYCPCLYIVQVFDNTPAALDGTVAAGDEITGVNGKSIKGKTKVEVAKMIQEVKGEVTIHYNKLQADPKQGMSLDIVLKKVKHRLVENMSSGTADALGLSRAILCNDGLVKRLEELERTAELYKGMTEHTKNLLRAFYELSQ----THRAFGDVFSVIGVREPQPAASEAFVKFADAHRSIEKFG 221

HSP 2 Score: 184.882 bits (468), Expect = 1.623e-96
Identity = 84/127 (66.14%), Postives = 103/127 (81.10%), Query Frame = 3 
Query:  819 VIPDTKLTIKKYLEAKFEYLSYCLKVKEMDDEELCYVALHEALYRIETGNYEYRLLLRCRQNSRKKFSKMRNDVLEKMELLDNKHVQDIVKNLGKFMDILKQYYNDNYSAWKNAQIFPIEIDISSLT 1199
             IPDT+LTIKKYL+ KFEYLSYCLKVKEMDDEE   +AL E LYR+ TGNYEYRL+LRCRQ +R +FS+MR DVLEKMELLD KHVQDIV  L +F+  + +YYND Y+  ++A +FPIE+D++  T
Sbjct:  242 AIPDTRLTIKKYLDVKFEYLSYCLKVKEMDDEEYSCIALGEPLYRVSTGNYEYRLILRCRQEARARFSQMRKDVLEKMELLDQKHVQDIVFQLQRFVSTMSKYYNDCYAVLQDADVFPIEVDLAHTT 368
[Close]
BLAST of PRKCA-binding protein vs. Ensembl Mouse
Match: Pick1 (protein interacting with C kinase 1 [Source:MGI Symbol;Acc:MGI:894645])

HSP 1 Score: 188.734 bits (478), Expect = 1.623e-96
Identity = 113/216 (52.31%), Postives = 151/216 (69.91%), Query Frame = 1 
Query:  127 QEDKCGMRVTSGSVVLNKDKHSLXXXXXXXXXXXXXXXXXVQIFDNTVAAKDGTLEAGDEVTAIDKKSVKGVSRGEVAKWIQKAENKVTIYYNKLHLDKNQGKSVEMIFKRFKHRLVENIDSSTADFLGLSRAILVNDSLMKRLELLNQTSHLFEDLS----NFISKFNEESKESAIIHKKMAEVFENIGVKEPQANASEAFLIFAKGQRCMQKYS 762
            +EDK G+    G V L KD  +LIGISIGGG  YCPC+YIVQ+FDNT AA DGT+ AGDE+T ++ KS+KG ++ EVAK IQ+ + +VTI+YNKL  D  QG S++++ K+ KHRLVEN+ S TAD LGLSRAIL ND L+KRLE L +T+ L++ ++    N +  F E S+     H+   +VF  IGV+EPQ  ASEAF+ FA   R ++K+ 
Sbjct:   10 EEDKLGIPTVPGKVTLQKDAQNLIGISIGGGAQYCPCLYIVQVFDNTPAALDGTVAAGDEITGVNGKSIKGKTKVEVAKMIQEVKGEVTIHYNKLQADPKQGMSLDIVLKKVKHRLVENMSSGTADALGLSRAILCNDGLVKRLEELERTAELYKGMTEHTKNLLRAFYELSQ----THRAFGDVFSVIGVREPQPAASEAFVKFADAHRSIEKFG 221

HSP 2 Score: 184.882 bits (468), Expect = 1.623e-96
Identity = 84/127 (66.14%), Postives = 103/127 (81.10%), Query Frame = 3 
Query:  819 VIPDTKLTIKKYLEAKFEYLSYCLKVKEMDDEELCYVALHEALYRIETGNYEYRLLLRCRQNSRKKFSKMRNDVLEKMELLDNKHVQDIVKNLGKFMDILKQYYNDNYSAWKNAQIFPIEIDISSLT 1199
             IPDT+LTIKKYL+ KFEYLSYCLKVKEMDDEE   +AL E LYR+ TGNYEYRL+LRCRQ +R +FS+MR DVLEKMELLD KHVQDIV  L +F+  + +YYND Y+  ++A +FPIE+D++  T
Sbjct:  242 AIPDTRLTIKKYLDVKFEYLSYCLKVKEMDDEEYSCIALGEPLYRVSTGNYEYRLILRCRQEARARFSQMRKDVLEKMELLDQKHVQDIVFQLQRFVSTMSKYYNDCYAVLQDADVFPIEVDLAHTT 368
[Close]
BLAST of PRKCA-binding protein vs. Ensembl Mouse
Match: Gm49486 (predicted gene, 49486 [Source:MGI Symbol;Acc:MGI:6155161])

HSP 1 Score: 189.119 bits (479), Expect = 7.763e-84
Identity = 113/216 (52.31%), Postives = 151/216 (69.91%), Query Frame = 1 
Query:  127 QEDKCGMRVTSGSVVLNKDKHSLXXXXXXXXXXXXXXXXXVQIFDNTVAAKDGTLEAGDEVTAIDKKSVKGVSRGEVAKWIQKAENKVTIYYNKLHLDKNQGKSVEMIFKRFKHRLVENIDSSTADFLGLSRAILVNDSLMKRLELLNQTSHLFEDLS----NFISKFNEESKESAIIHKKMAEVFENIGVKEPQANASEAFLIFAKGQRCMQKYS 762
            +EDK G+    G V L KD  +LIGISIGGG  YCPC+YIVQ+FDNT AA DGT+ AGDE+T ++ KS+KG ++ EVAK IQ+ + +VTI+YNKL  D  QG S++++ K+ KHRLVEN+ S TAD LGLSRAIL ND L+KRLE L +T+ L++ ++    N +  F E S+     H+   +VF  IGV+EPQ  ASEAF+ FA   R ++K+ 
Sbjct:   10 EEDKLGIPTVPGKVTLQKDAQNLIGISIGGGAQYCPCLYIVQVFDNTPAALDGTVAAGDEITGVNGKSIKGKTKVEVAKMIQEVKGEVTIHYNKLQADPKQGMSLDIVLKKVKHRLVENMSSGTADALGLSRAILCNDGLVKRLEELERTAELYKGMTEHTKNLLRAFYELSQ----THRAFGDVFSVIGVREPQPAASEAFVKFADAHRSIEKFG 221

HSP 2 Score: 142.124 bits (357), Expect = 7.763e-84
Identity = 65/85 (76.47%), Postives = 73/85 (85.88%), Query Frame = 3 
Query:  819 VIPDTKLTIKKYLEAKFEYLSYCLKVKEMDDEELCYVALHEALYRIETGNYEYRLLLRCRQNSRKKFSKMRNDVLEKMELLDNKH 1073
             IPDT+LTIKKYL+ KFEYLSYCLKVKEMDDEE   +AL E LYR+ TGNYEYRL+LRCRQ +R +FS+MR DVLEKMELLD KH
Sbjct:  242 AIPDTRLTIKKYLDVKFEYLSYCLKVKEMDDEEYSCIALGEPLYRVSTGNYEYRLILRCRQEARARFSQMRKDVLEKMELLDQKH 326
[Close]
BLAST of PRKCA-binding protein vs. UniProt/SwissProt
Match: sp|Q2T9M1|PICK1_BOVIN (PRKCA-binding protein OS=Bos taurus OX=9913 GN=PICK1 PE=2 SV=1)

HSP 1 Score: 188.348 bits (477), Expect = 1.221e-95
Identity = 112/216 (51.85%), Postives = 151/216 (69.91%), Query Frame = 1 
Query:  127 QEDKCGMRVTSGSVVLNKDKHSLXXXXXXXXXXXXXXXXXVQIFDNTVAAKDGTLEAGDEVTAIDKKSVKGVSRGEVAKWIQKAENKVTIYYNKLHLDKNQGKSVEMIFKRFKHRLVENIDSSTADFLGLSRAILVNDSLMKRLELLNQTSHLFEDLS----NFISKFNEESKESAIIHKKMAEVFENIGVKEPQANASEAFLIFAKGQRCMQKYS 762
            +EDK G+    G V L KD  +LIGISIGGG  YCPC+YIVQ+FDNT AA DGT+ AGDE+T ++ +S+KG ++ EVAK IQ+ + +VTI+YNKL  D  QG S++++ K+ KHRLVEN+ S TAD LGLSRAIL ND L+KRLE L +T+ L++ ++    N +  F E S+     H+   +VF  IGV+EPQ  ASEAF+ FA   R ++K+ 
Sbjct:   10 EEDKLGIPTVPGKVTLQKDAQNLIGISIGGGAQYCPCLYIVQVFDNTPAALDGTVAAGDEITGVNGRSIKGKTKVEVAKMIQEVKGEVTIHYNKLQADPKQGMSLDIVLKKVKHRLVENMSSGTADALGLSRAILCNDGLVKRLEELERTAELYKGMTEHTKNLLRAFYELSQ----THRAFGDVFSVIGVREPQPAASEAFVKFADAHRSIEKFG 221

HSP 2 Score: 184.882 bits (468), Expect = 1.221e-95
Identity = 84/127 (66.14%), Postives = 103/127 (81.10%), Query Frame = 3 
Query:  819 VIPDTKLTIKKYLEAKFEYLSYCLKVKEMDDEELCYVALHEALYRIETGNYEYRLLLRCRQNSRKKFSKMRNDVLEKMELLDNKHVQDIVKNLGKFMDILKQYYNDNYSAWKNAQIFPIEIDISSLT 1199
             IPDT+LTIKKYL+ KFEYLSYCLKVKEMDDEE   +AL E LYR+ TGNYEYRL+LRCRQ +R +FS+MR DVLEKMELLD +HVQDIV  L +F+  + +YYND YS  ++A +FPIE+D++  T
Sbjct:  242 AIPDTRLTIKKYLDVKFEYLSYCLKVKEMDDEEYSCIALGEPLYRVSTGNYEYRLILRCRQEARARFSQMRKDVLEKMELLDQEHVQDIVLQLQRFVSTMSKYYNDCYSVLRDADVFPIEVDLAHTT 368
[Close]
BLAST of PRKCA-binding protein vs. UniProt/SwissProt
Match: sp|Q9EP80|PICK1_RAT (PRKCA-binding protein OS=Rattus norvegicus OX=10116 GN=Pick1 PE=1 SV=1)

HSP 1 Score: 187.963 bits (476), Expect = 1.372e-95
Identity = 112/216 (51.85%), Postives = 151/216 (69.91%), Query Frame = 1 
Query:  127 QEDKCGMRVTSGSVVLNKDKHSLXXXXXXXXXXXXXXXXXVQIFDNTVAAKDGTLEAGDEVTAIDKKSVKGVSRGEVAKWIQKAENKVTIYYNKLHLDKNQGKSVEMIFKRFKHRLVENIDSSTADFLGLSRAILVNDSLMKRLELLNQTSHLFEDLS----NFISKFNEESKESAIIHKKMAEVFENIGVKEPQANASEAFLIFAKGQRCMQKYS 762
            +EDK G+    G V L KD  +LIGISIGGG  YCPC+YIVQ+FDNT AA DGT+ AGDE+T ++ +S+KG ++ EVAK IQ+ + +VTI+YNKL  D  QG S++++ K+ KHRLVEN+ S TAD LGLSRAIL ND L+KRLE L +T+ L++ ++    N +  F E S+     H+   +VF  IGV+EPQ  ASEAF+ FA   R ++K+ 
Sbjct:   10 EEDKLGIPTVPGKVTLQKDAQNLIGISIGGGAQYCPCLYIVQVFDNTPAALDGTVAAGDEITGVNGRSIKGKTKVEVAKMIQEVKGEVTIHYNKLQADPKQGMSLDIVLKKVKHRLVENMSSGTADALGLSRAILCNDGLVKRLEELERTAELYKGMTEHTKNLLRAFYELSQ----THRAFGDVFSVIGVREPQPAASEAFVKFADAHRSIEKFG 221

HSP 2 Score: 185.267 bits (469), Expect = 1.372e-95
Identity = 84/127 (66.14%), Postives = 103/127 (81.10%), Query Frame = 3 
Query:  819 VIPDTKLTIKKYLEAKFEYLSYCLKVKEMDDEELCYVALHEALYRIETGNYEYRLLLRCRQNSRKKFSKMRNDVLEKMELLDNKHVQDIVKNLGKFMDILKQYYNDNYSAWKNAQIFPIEIDISSLT 1199
             IPDT+LTIKKYL+ KFEYLSYCLKVKEMDDEE   +AL E LYR+ TGNYEYRL+LRCRQ +R +FS+MR DVLEKMELLD KHVQDIV  L +F+  + +YYND Y+  ++A +FPIE+D++  T
Sbjct:  242 AIPDTRLTIKKYLDVKFEYLSYCLKVKEMDDEEYSCIALGEPLYRVSTGNYEYRLILRCRQEARARFSQMRKDVLEKMELLDQKHVQDIVFQLQRFVSTMSKYYNDCYAVLRDADVFPIEVDLAHTT 368
[Close]
BLAST of PRKCA-binding protein vs. UniProt/SwissProt
Match: sp|Q5REH1|PICK1_PONAB (PRKCA-binding protein OS=Pongo abelii OX=9601 GN=PICK1 PE=2 SV=1)

HSP 1 Score: 187.963 bits (476), Expect = 7.535e-95
Identity = 112/216 (51.85%), Postives = 151/216 (69.91%), Query Frame = 1 
Query:  127 QEDKCGMRVTSGSVVLNKDKHSLXXXXXXXXXXXXXXXXXVQIFDNTVAAKDGTLEAGDEVTAIDKKSVKGVSRGEVAKWIQKAENKVTIYYNKLHLDKNQGKSVEMIFKRFKHRLVENIDSSTADFLGLSRAILVNDSLMKRLELLNQTSHLFEDLS----NFISKFNEESKESAIIHKKMAEVFENIGVKEPQANASEAFLIFAKGQRCMQKYS 762
            +EDK G+    G V L KD  +LIGISIGGG  YCPC+YIVQ+FDNT AA DGT+ AGDE+T ++ +S+KG ++ EVAK IQ+ + +VTI+YNKL  D  QG S++++ K+ KHRLVEN+ S TAD LGLSRAIL ND L+KRLE L +T+ L++ ++    N +  F E S+     H+   +VF  IGV+EPQ  ASEAF+ FA   R ++K+ 
Sbjct:   10 EEDKLGIPTVPGKVTLQKDAQNLIGISIGGGAQYCPCLYIVQVFDNTPAALDGTVAAGDEITGVNGRSIKGKTKVEVAKMIQEVKGEVTIHYNKLQADPKQGMSLDIVLKKVKHRLVENMSSGTADALGLSRAILCNDGLVKRLEELERTAELYKGMTEHTKNLLRAFYELSQ----THRAFGDVFSVIGVREPQPAASEAFVKFADAHRSIEKFG 221

HSP 2 Score: 182.956 bits (463), Expect = 7.535e-95
Identity = 83/127 (65.35%), Postives = 102/127 (80.31%), Query Frame = 3 
Query:  819 VIPDTKLTIKKYLEAKFEYLSYCLKVKEMDDEELCYVALHEALYRIETGNYEYRLLLRCRQNSRKKFSKMRNDVLEKMELLDNKHVQDIVKNLGKFMDILKQYYNDNYSAWKNAQIFPIEIDISSLT 1199
             IPDT+LTIKKYL+ KFEYLSYCLKVKEMDDEE   +AL E LYR+ TGNYEYRL+LRCRQ +R +FS+MR DVLEKMELLD KHVQDIV  L + +  + +YYND Y+  ++A +FPIE+D++  T
Sbjct:  242 AIPDTRLTIKKYLDVKFEYLSYCLKVKEMDDEEYSCIALGEPLYRVSTGNYEYRLILRCRQEARARFSQMRKDVLEKMELLDQKHVQDIVFQLQRLVSTMSKYYNDCYAVLRDADVFPIEVDLAHTT 368
[Close]
BLAST of PRKCA-binding protein vs. UniProt/SwissProt
Match: sp|Q9NRD5|PICK1_HUMAN (PRKCA-binding protein OS=Homo sapiens OX=9606 GN=PICK1 PE=1 SV=2)

HSP 1 Score: 187.963 bits (476), Expect = 7.920e-95
Identity = 112/216 (51.85%), Postives = 151/216 (69.91%), Query Frame = 1 
Query:  127 QEDKCGMRVTSGSVVLNKDKHSLXXXXXXXXXXXXXXXXXVQIFDNTVAAKDGTLEAGDEVTAIDKKSVKGVSRGEVAKWIQKAENKVTIYYNKLHLDKNQGKSVEMIFKRFKHRLVENIDSSTADFLGLSRAILVNDSLMKRLELLNQTSHLFEDLS----NFISKFNEESKESAIIHKKMAEVFENIGVKEPQANASEAFLIFAKGQRCMQKYS 762
            +EDK G+    G V L KD  +LIGISIGGG  YCPC+YIVQ+FDNT AA DGT+ AGDE+T ++ +S+KG ++ EVAK IQ+ + +VTI+YNKL  D  QG S++++ K+ KHRLVEN+ S TAD LGLSRAIL ND L+KRLE L +T+ L++ ++    N +  F E S+     H+   +VF  IGV+EPQ  ASEAF+ FA   R ++K+ 
Sbjct:   10 EEDKLGIPTVPGKVTLQKDAQNLIGISIGGGAQYCPCLYIVQVFDNTPAALDGTVAAGDEITGVNGRSIKGKTKVEVAKMIQEVKGEVTIHYNKLQADPKQGMSLDIVLKKVKHRLVENMSSGTADALGLSRAILCNDGLVKRLEELERTAELYKGMTEHTKNLLRAFYELSQ----THRAFGDVFSVIGVREPQPAASEAFVKFADAHRSIEKFG 221

HSP 2 Score: 182.57 bits (462), Expect = 7.920e-95
Identity = 83/127 (65.35%), Postives = 102/127 (80.31%), Query Frame = 3 
Query:  819 VIPDTKLTIKKYLEAKFEYLSYCLKVKEMDDEELCYVALHEALYRIETGNYEYRLLLRCRQNSRKKFSKMRNDVLEKMELLDNKHVQDIVKNLGKFMDILKQYYNDNYSAWKNAQIFPIEIDISSLT 1199
             IPDT+LTIKKYL+ KFEYLSYCLKVKEMDDEE   +AL E LYR+ TGNYEYRL+LRCRQ +R +FS+MR DVLEKMELLD KHVQDIV  L + +  + +YYND Y+  ++A +FPIE+D++  T
Sbjct:  242 AIPDTRLTIKKYLDVKFEYLSYCLKVKEMDDEEYSCIALGEPLYRVSTGNYEYRLILRCRQEARARFSQMRKDVLEKMELLDQKHVQDIVFQLQRLVSTMSKYYNDCYAVLRDADVFPIEVDLAHTT 368
[Close]
BLAST of PRKCA-binding protein vs. UniProt/SwissProt
Match: sp|Q62083|PICK1_MOUSE (PRKCA-binding protein OS=Mus musculus OX=10090 GN=Pick1 PE=1 SV=2)

HSP 1 Score: 188.734 bits (478), Expect = 1.077e-94
Identity = 113/216 (52.31%), Postives = 151/216 (69.91%), Query Frame = 1 
Query:  127 QEDKCGMRVTSGSVVLNKDKHSLXXXXXXXXXXXXXXXXXVQIFDNTVAAKDGTLEAGDEVTAIDKKSVKGVSRGEVAKWIQKAENKVTIYYNKLHLDKNQGKSVEMIFKRFKHRLVENIDSSTADFLGLSRAILVNDSLMKRLELLNQTSHLFEDLS----NFISKFNEESKESAIIHKKMAEVFENIGVKEPQANASEAFLIFAKGQRCMQKYS 762
            +EDK G+    G V L KD  +LIGISIGGG  YCPC+YIVQ+FDNT AA DGT+ AGDE+T ++ KS+KG ++ EVAK IQ+ + +VTI+YNKL  D  QG S++++ K+ KHRLVEN+ S TAD LGLSRAIL ND L+KRLE L +T+ L++ ++    N +  F E S+     H+   +VF  IGV+EPQ  ASEAF+ FA   R ++K+ 
Sbjct:   10 EEDKLGIPTVPGKVTLQKDAQNLIGISIGGGAQYCPCLYIVQVFDNTPAALDGTVAAGDEITGVNGKSIKGKTKVEVAKMIQEVKGEVTIHYNKLQADPKQGMSLDIVLKKVKHRLVENMSSGTADALGLSRAILCNDGLVKRLEELERTAELYKGMTEHTKNLLRAFYELSQ----THRAFGDVFSVIGVREPQPAASEAFVKFADAHRSIEKFG 221

HSP 2 Score: 181.415 bits (459), Expect = 1.077e-94
Identity = 82/127 (64.57%), Postives = 101/127 (79.53%), Query Frame = 3 
Query:  819 VIPDTKLTIKKYLEAKFEYLSYCLKVKEMDDEELCYVALHEALYRIETGNYEYRLLLRCRQNSRKKFSKMRNDVLEKMELLDNKHVQDIVKNLGKFMDILKQYYNDNYSAWKNAQIFPIEIDISSLT 1199
             IPDT+LTIKKYL+ KFEYLSYCLKVKEMDDEE   +    ALYR+ TGNYEYRL+LRCRQ +R +FS+MR DVLEKMELLD KHVQDIV  L +F+  + +YYND Y+  ++A +FPIE+D++  T
Sbjct:  242 AIPDTRLTIKKYLDVKFEYLSYCLKVKEMDDEEYSCIGPRRALYRVSTGNYEYRLILRCRQEARARFSQMRKDVLEKMELLDQKHVQDIVFQLQRFVSTMSKYYNDCYAVLQDADVFPIEVDLAHTT 368
[Close]
BLAST of PRKCA-binding protein vs. TrEMBL
Match: A0A210QSU7 (PRKCA-binding protein OS=Mizuhopecten yessoensis OX=6573 GN=KP79_PYT05633 PE=4 SV=1)

HSP 1 Score: 199.904 bits (507), Expect = 1.253e-96
Identity = 117/212 (55.19%), Postives = 155/212 (73.11%), Query Frame = 1 
Query:  127 QEDKCGMRVTSGSVVLNKDKHSLXXXXXXXXXXXXXXXXXVQIFDNTVAAKDGTLEAGDEVTAIDKKSVKGVSRGEVAKWIQKAENKVTIYYNKLHLDKNQGKSVEMIFKRFKHRLVENIDSSTADFLGLSRAILVNDSLMKRLELLNQTSHLFEDLSNFISKFNEESKESAIIHKKMAEVFENIGVKEPQANASEAFLIFAKGQRCMQKYS 762
            +EDK GMRVTSGS+VL KD  +LIGISIGGG P CPC+Y+VQIFDNT AAKD TL +GDE+T ++ +S KG S+ EVAK IQ     VTI YNKLH D  QGKS++++ K+ KHR+VE ++++TAD LGLSRAIL ND L+K+LE L +T+ +++ L +   K  + + E +  HK   EVF  IGV+EPQ  ASEAF +F +  R M+K++
Sbjct:   13 EEDKLGMRVTSGSIVLKKDTQNLIGISIGGGAPLCPCLYVVQIFDNTPAAKDSTLASGDEITGVNGQSAKGKSKVEVAKMIQSISESVTINYNKLHADPKQGKSLDIVLKKVKHRVVETMNTNTADALGLSRAILCNDGLVKKLEELEKTADMYKGLIDQTKKLLKSTFELSQSHKAFGEVFSGIGVREPQPAASEAFSMFGEAHRNMEKFA 224

HSP 2 Score: 184.496 bits (467), Expect = 1.253e-96
Identity = 85/134 (63.43%), Postives = 104/134 (77.61%), Query Frame = 3 
Query:  819 VIPDTKLTIKKYLEAKFEYLSYCLKVKEMDDEELCYVALHEALYRIETGNYEYRLLLRCRQNSRKKFSKMRNDVLEKMELLDNKHVQDIVKNLGKFMDILKQYYNDNYSAWKNAQIFPIEIDISSLTHINDEFN 1220
             +PDT+LTIKKYL+ KFEYL+YCLKVKEMDDEE  Y AL E LYR+ETGNYEYRL+LRCRQ++R +F+KMR DVL KMELLD KHVQDIV  L +F+  + +Y+ND +   K A +FPIE+D+S  T   D  N
Sbjct:  245 AVPDTRLTIKKYLDVKFEYLAYCLKVKEMDDEEYSYAALQEPLYRVETGNYEYRLVLRCRQDARHRFAKMRADVLVKMELLDQKHVQDIVFQLQRFVSAMAKYHNDCHGVMKKAVVFPIEVDLSRGTFTYDTSN 378
[Close]
BLAST of PRKCA-binding protein vs. TrEMBL
Match: A0A0B7AE74 (Uncharacterized protein OS=Arion vulgaris OX=1028688 GN=ORF112509 PE=4 SV=1)

HSP 1 Score: 193.741 bits (491), Expect = 1.607e-95
Identity = 114/215 (53.02%), Postives = 154/215 (71.63%), Query Frame = 1 
Query:  118 SFPQEDKCGMRVTSGSVVLNKDKHSLXXXXXXXXXXXXXXXXXVQIFDNTVAAKDGTLEAGDEVTAIDKKSVKGVSRGEVAKWIQKAENKVTIYYNKLHLDKNQGKSVEMIFKRFKHRLVENIDSSTADFLGLSRAILVNDSLMKRLELLNQTSHLFEDLSNFISKFNEESKESAIIHKKMAEVFENIGVKEPQANASEAFLIFAKGQRCMQKYS 762
              P ED  GM VTSG VVL KD  +LIGISIGGG P CPC+Y+VQ+FDNT AAKDG L AGDE+  ++ +SVKG ++ EVA+ IQ  +++VTI YNKLH D  QGKS++++ K+ KHR+VEN++S+TAD LGLSRAIL ND L+K+LE + +T++++  L     K  +   + +  HK   EVF +IGV+EPQ  ASEAF  F +  R M+K++
Sbjct:   28 PMPWEDNMGMTVTSGHVVLKKDTQNLIGISIGGGAPLCPCLYVVQVFDNTPAAKDGALAAGDEIVGVNGQSVKGRTKVEVARMIQSIKSEVTINYNKLHADPKQGKSLDIVLKKVKHRVVENMNSNTADALGLSRAILCNDGLLKKLEEMERTANMYGGLIIQTRKLLKAIFDLSQSHKAFGEVFADIGVREPQPAASEAFSQFGEAHRNMEKFA 242

HSP 2 Score: 187.193 bits (474), Expect = 1.607e-95
Identity = 86/135 (63.70%), Postives = 106/135 (78.52%), Query Frame = 3 
Query:  819 VIPDTKLTIKKYLEAKFEYLSYCLKVKEMDDEELCYVALHEALYRIETGNYEYRLLLRCRQNSRKKFSKMRNDVLEKMELLDNKHVQDIVKNLGKFMDILKQYYNDNYSAWKNAQIFPIEIDISSLTHINDEFNA 1223
             +PDT+LT+KKYL+AKFEYLSYCLKVKEMDDEE  Y AL E LYR+ETGNYEYRL+LRCRQ +R +F+KMR+DVL KMELLD KHVQDIV  L KF+  + +Y+ D ++  K A +FPIE+D+S  T   D  N+
Sbjct:  263 AVPDTRLTVKKYLDAKFEYLSYCLKVKEMDDEEYSYAALQEPLYRVETGNYEYRLVLRCRQEARSRFAKMRSDVLVKMELLDQKHVQDIVFQLQKFVTAMAKYHTDCHNVMKTAVVFPIEVDLSRGTFTYDTANS 397
[Close]
BLAST of PRKCA-binding protein vs. TrEMBL
Match: I6YMZ0 (PICK1 OS=Aplysia californica OX=6500 PE=2 SV=1)

HSP 1 Score: 193.741 bits (491), Expect = 2.415e-95
Identity = 115/221 (52.04%), Postives = 160/221 (72.40%), Query Frame = 1 
Query:  100 FEDIMNSFPQEDKCGMRVTSGSVVLNKDKHSLXXXXXXXXXXXXXXXXXVQIFDNTVAAKDGTLEAGDEVTAIDKKSVKGVSRGEVAKWIQKAENKVTIYYNKLHLDKNQGKSVEMIFKRFKHRLVENIDSSTADFLGLSRAILVNDSLMKRLELLNQTSHLFEDLSNFISKFNEESKESAIIHKKMAEVFENIGVKEPQANASEAFLIFAKGQRCMQKYS 762
            F+++++   +EDK GM VTSG VVL KD  +LIGISIGGG P CPC+Y+VQ+FDNT AAK+G+L AGDE+  ++ +SVKG ++ EVA+ IQ  + +VTI YNKLH D  QGKS+++I K+ KHR+VEN++S+TAD LGLSRAIL ND L+K+LE + +T++++  L     K  +   + +  HK   EVF  IGV+EPQ  ASEAF  F +  R M+K++
Sbjct:    2 FDEMLDYEVEEDKLGMTVTSGHVVLKKDTQNLIGISIGGGAPLCPCLYVVQVFDNTPAAKEGSLAAGDEIVGVNGQSVKGRTKVEVARMIQSIKAEVTINYNKLHADPKQGKSLDIILKKVKHRVVENMNSNTADALGLSRAILCNDGLLKKLEEMERTANMYGGLIVQTRKLLKAIFDLSQSHKAFGEVFSGIGVREPQPAASEAFSQFGEAHRNMEKFA 222

HSP 2 Score: 186.808 bits (473), Expect = 2.415e-95
Identity = 86/134 (64.18%), Postives = 105/134 (78.36%), Query Frame = 3 
Query:  819 VIPDTKLTIKKYLEAKFEYLSYCLKVKEMDDEELCYVALHEALYRIETGNYEYRLLLRCRQNSRKKFSKMRNDVLEKMELLDNKHVQDIVKNLGKFMDILKQYYNDNYSAWKNAQIFPIEIDISSLTHINDEFN 1220
             +PDT+LT+KKYL+AKFEYLSYCLKVKEMDDEE  Y AL E LYR+ETGNYEYRL+LRCRQ +R +F+KMR+DVL KMELLD KHVQDIV  L KF+  + +Y+ D ++  K A +FPIE+D+S  T   D  N
Sbjct:  243 AVPDTRLTVKKYLDAKFEYLSYCLKVKEMDDEEYSYAALQEPLYRVETGNYEYRLVLRCRQEARTRFAKMRSDVLVKMELLDQKHVQDIVFQLQKFVTAMAKYHTDCHNVMKTAVVFPIEVDLSRGTFTYDTAN 376
[Close]
BLAST of PRKCA-binding protein vs. TrEMBL
Match: A0A3S0ZXP0 (Uncharacterized protein OS=Elysia chlorotica OX=188477 GN=EGW08_003712 PE=4 SV=1)

HSP 1 Score: 192.971 bits (489), Expect = 1.315e-94
Identity = 117/233 (50.21%), Postives = 160/233 (68.67%), Query Frame = 1 
Query:   64 VKTLDPDFEVIEFEDIMNSFPQEDKCGMRVTSGSVVLNKDKHSLXXXXXXXXXXXXXXXXXVQIFDNTVAAKDGTLEAGDEVTAIDKKSVKGVSRGEVAKWIQKAENKVTIYYNKLHLDKNQGKSVEMIFKRFKHRLVENIDSSTADFLGLSRAILVNDSLMKRLELLNQTSHLFEDLSNFISKFNEESKESAIIHKKMAEVFENIGVKEPQANASEAFLIFAKGQRCMQKYS 762
            V T+D D EV    +     P ED  GM VTSG VVL KD  +LIGISIGGG P CPC+Y+VQ+FDNT A+K+G+L AGDE+  ++ +SVKG ++ EVA+ IQ  + +VTI YNKLH D  QGKS++++ K+ KHR+VEN++S+TAD LGLSRAIL ND L+K+LE + +T+ ++  L     K  +   + +  H+   EVF  IGV+EPQ  ASEAF  F +  R M+K++
Sbjct:   11 VSTMDLD-EVYADHNKHQPMPWEDHMGMTVTSGHVVLKKDTQNLIGISIGGGAPLCPCLYVVQVFDNTPASKEGSLAAGDEIVGVNGQSVKGRTKVEVARMIQSIKAEVTINYNKLHADPKQGKSLDIVLKKVKHRVVENMNSNTADALGLSRAILCNDGLLKKLEEMERTATMYSGLIVQTRKLLKAIFDLSQSHRAFGEVFAGIGVREPQPGASEAFTQFGEAHRMMEKFA 242

HSP 2 Score: 184.882 bits (468), Expect = 1.315e-94
Identity = 84/134 (62.69%), Postives = 105/134 (78.36%), Query Frame = 3 
Query:  819 VIPDTKLTIKKYLEAKFEYLSYCLKVKEMDDEELCYVALHEALYRIETGNYEYRLLLRCRQNSRKKFSKMRNDVLEKMELLDNKHVQDIVKNLGKFMDILKQYYNDNYSAWKNAQIFPIEIDISSLTHINDEFN 1220
             +PDT+LT++KYL++KFEYLSYCLKVKEMDDEE  Y AL E LYR+ETGNYEYRL+LRCRQ++R +F+KMR+DVL KMELLD KHVQDIV  L KF+  + +Y+ D +   K A +FPIE+D+S  T   D  N
Sbjct:  263 AVPDTRLTVRKYLDSKFEYLSYCLKVKEMDDEEYSYAALQEPLYRVETGNYEYRLVLRCRQDARTRFAKMRSDVLVKMELLDQKHVQDIVFQLQKFVTAMAKYHTDCHEVMKGAVVFPIEVDLSRGTFTYDTAN 396
[Close]
BLAST of PRKCA-binding protein vs. TrEMBL
Match: A0A5J5N549 (Uncharacterized protein OS=Muntiacus reevesi OX=9886 GN=FD755_002308 PE=4 SV=1)

HSP 1 Score: 188.734 bits (478), Expect = 2.113e-94
Identity = 85/127 (66.93%), Postives = 104/127 (81.89%), Query Frame = 3 
Query:  819 VIPDTKLTIKKYLEAKFEYLSYCLKVKEMDDEELCYVALHEALYRIETGNYEYRLLLRCRQNSRKKFSKMRNDVLEKMELLDNKHVQDIVKNLGKFMDILKQYYNDNYSAWKNAQIFPIEIDISSLT 1199
             IPDT+LTIKKYL+ KFEYLSYCLKVKEMDDEE  Y+AL E LYR+ TGNYEYRL+LRCRQ +R +FS+MR DVLEKMELLD KHVQDIV  L +F+  + +YYND Y+  ++A +FPIE+D++  T
Sbjct:  242 AIPDTRLTIKKYLDVKFEYLSYCLKVKEMDDEEYSYIALGEPLYRVSTGNYEYRLILRCRQEARARFSQMRKDVLEKMELLDQKHVQDIVFQLQRFVSTMSKYYNDCYAVLRDADVFPIEVDLAHTT 368

HSP 2 Score: 188.348 bits (477), Expect = 2.113e-94
Identity = 112/216 (51.85%), Postives = 151/216 (69.91%), Query Frame = 1 
Query:  127 QEDKCGMRVTSGSVVLNKDKHSLXXXXXXXXXXXXXXXXXVQIFDNTVAAKDGTLEAGDEVTAIDKKSVKGVSRGEVAKWIQKAENKVTIYYNKLHLDKNQGKSVEMIFKRFKHRLVENIDSSTADFLGLSRAILVNDSLMKRLELLNQTSHLFEDLS----NFISKFNEESKESAIIHKKMAEVFENIGVKEPQANASEAFLIFAKGQRCMQKYS 762
            +EDK G+    G V L KD  +LIGISIGGG  YCPC+YIVQ+FDNT AA DGT+ AGDE+T ++ +S+KG ++ EVAK IQ+ + +VTI+YNKL  D  QG S++++ K+ KHRLVEN+ S TAD LGLSRAIL ND L+KRLE L +T+ L++ ++    N +  F E S+     H+   +VF  IGV+EPQ  ASEAF+ FA   R ++K+ 
Sbjct:   10 EEDKLGIPTVPGKVTLQKDAQNLIGISIGGGAQYCPCLYIVQVFDNTPAALDGTVAAGDEITGVNGRSIKGKTKVEVAKMIQEVKGEVTIHYNKLQADPKQGMSLDIVLKKVKHRLVENMSSGTADALGLSRAILCNDGLVKRLEELERTAELYKGMTEHTKNLLRAFYELSQ----THRAFGDVFSVIGVREPQPAASEAFVKFADAHRSIEKFG 221
[Close]
BLAST of PRKCA-binding protein vs. Ensembl Cavefish
Match: pick1 (protein interacting with PRKCA 1 [Source:NCBI gene;Acc:103045423])

HSP 1 Score: 192.586 bits (488), Expect = 3.109e-96
Identity = 116/221 (52.49%), Postives = 151/221 (68.33%), Query Frame = 1 
Query:  100 FEDIMNSFPQEDKCGMRVTSGSVVLNKDKHSLXXXXXXXXXXXXXXXXXVQIFDNTVAAKDGTLEAGDEVTAIDKKSVKGVSRGEVAKWIQKAENKVTIYYNKLHLDKNQGKSVEMIFKRFKHRLVENIDSSTADFLGLSRAILVNDSLMKRLELLNQTSHLFEDLSNFISKFNEESKESAIIHKKMAEVFENIGVKEPQANASEAFLIFAKGQRCMQKYS 762
            F D M+   +EDK G+    G+V L KD  +LIGISIGGG  YCPC+YIVQ+FDNT AA DGTL AGDE+T ++ K VKG ++ EVAK IQ  + +  I+YNKL  D  QGKS++++ K+ KHRLVEN+ S TAD LGLSRAIL ND L+K+LE L +TS L++ L     +      E +  H+   +VF  IGV+EPQA ASEAF+ FA+  R ++KY 
Sbjct:    2 FTDSMDYELEEDKLGIPTVPGTVTLKKDAQNLIGISIGGGAQYCPCLYIVQVFDNTPAALDGTLAAGDEITGVNGKPVKGKTKVEVAKMIQAVQGEAVIHYNKLQADPKQGKSLDIVLKKVKHRLVENLSSGTADALGLSRAILCNDGLVKKLEELEKTSELYKGLMEHSKRLLRAFFELSQTHRAFGDVFSVIGVREPQAAASEAFVKFAEAHRNIEKYG 222

HSP 2 Score: 179.874 bits (455), Expect = 3.109e-96
Identity = 82/127 (64.57%), Postives = 102/127 (80.31%), Query Frame = 3 
Query:  819 VIPDTKLTIKKYLEAKFEYLSYCLKVKEMDDEELCYVALHEALYRIETGNYEYRLLLRCRQNSRKKFSKMRNDVLEKMELLDNKHVQDIVKNLGKFMDILKQYYNDNYSAWKNAQIFPIEIDISSLT 1199
             IPDT+LTI+KYL+ KFEYLSYCLKVKEMDDEE   +AL E LYR+ TGNYEYRL+LRCRQ +R +F+KMR DVLEK+ELLD KHVQDIV  L +F+  + +YY++ Y+  K A +FPIE+D+S  T
Sbjct:  243 AIPDTRLTIRKYLDVKFEYLSYCLKVKEMDDEEYSCIALGEPLYRVSTGNYEYRLILRCRQEARSRFAKMRKDVLEKIELLDQKHVQDIVFQLQRFVSGMSRYYDECYAVLKEADVFPIEVDLSRTT 369
[Close]
BLAST of PRKCA-binding protein vs. Ensembl Cavefish
Match: pick1 (protein interacting with PRKCA 1 [Source:NCBI gene;Acc:103045423])

HSP 1 Score: 192.586 bits (488), Expect = 3.109e-96
Identity = 116/221 (52.49%), Postives = 151/221 (68.33%), Query Frame = 1 
Query:  100 FEDIMNSFPQEDKCGMRVTSGSVVLNKDKHSLXXXXXXXXXXXXXXXXXVQIFDNTVAAKDGTLEAGDEVTAIDKKSVKGVSRGEVAKWIQKAENKVTIYYNKLHLDKNQGKSVEMIFKRFKHRLVENIDSSTADFLGLSRAILVNDSLMKRLELLNQTSHLFEDLSNFISKFNEESKESAIIHKKMAEVFENIGVKEPQANASEAFLIFAKGQRCMQKYS 762
            F D M+   +EDK G+    G+V L KD  +LIGISIGGG  YCPC+YIVQ+FDNT AA DGTL AGDE+T ++ K VKG ++ EVAK IQ  + +  I+YNKL  D  QGKS++++ K+ KHRLVEN+ S TAD LGLSRAIL ND L+K+LE L +TS L++ L     +      E +  H+   +VF  IGV+EPQA ASEAF+ FA+  R ++KY 
Sbjct:    2 FTDSMDYELEEDKLGIPTVPGTVTLKKDAQNLIGISIGGGAQYCPCLYIVQVFDNTPAALDGTLAAGDEITGVNGKPVKGKTKVEVAKMIQAVQGEAVIHYNKLQADPKQGKSLDIVLKKVKHRLVENLSSGTADALGLSRAILCNDGLVKKLEELEKTSELYKGLMEHSKRLLRAFFELSQTHRAFGDVFSVIGVREPQAAASEAFVKFAEAHRNIEKYG 222

HSP 2 Score: 179.874 bits (455), Expect = 3.109e-96
Identity = 82/127 (64.57%), Postives = 102/127 (80.31%), Query Frame = 3 
Query:  819 VIPDTKLTIKKYLEAKFEYLSYCLKVKEMDDEELCYVALHEALYRIETGNYEYRLLLRCRQNSRKKFSKMRNDVLEKMELLDNKHVQDIVKNLGKFMDILKQYYNDNYSAWKNAQIFPIEIDISSLT 1199
             IPDT+LTI+KYL+ KFEYLSYCLKVKEMDDEE   +AL E LYR+ TGNYEYRL+LRCRQ +R +F+KMR DVLEK+ELLD KHVQDIV  L +F+  + +YY++ Y+  K A +FPIE+D+S  T
Sbjct:  243 AIPDTRLTIRKYLDVKFEYLSYCLKVKEMDDEEYSCIALGEPLYRVSTGNYEYRLILRCRQEARSRFAKMRKDVLEKIELLDQKHVQDIVFQLQRFVSGMSRYYDECYAVLKEADVFPIEVDLSRTT 369
[Close]
BLAST of PRKCA-binding protein vs. Ensembl Sea Lamprey
Match: pick1 (protein interacting with prkca 1 [Source:ZFIN;Acc:ZDB-GENE-061013-283])

HSP 1 Score: 180.644 bits (457), Expect = 2.571e-54
Identity = 108/216 (50.00%), Postives = 149/216 (68.98%), Query Frame = 1 
Query:  127 QEDKCGMRVTSGSVVLNKDKHSLXXXXXXXXXXXXXXXXXVQIFDNTVAAKDGTLEAGDEVTAIDKKSVKGVSRGEVAKWIQKAENKVTIYYNKLHLDKNQGKSVEMIFKRFKHRLVENIDSSTADFLGLSRAILVNDSLMKRLELLNQTSHLFEDL----SNFISKFNEESKESAIIHKKMAEVFENIGVKEPQANASEAFLIFAKGQRCMQKYS 762
            +EDK G+    G VV+ KD  ++IGISIGGG P CPC+Y+VQ+FDN  AAKDGTL AGDE+  ++ KSVKG ++ EVAK IQ  + +VT+YYNKL  D   GK+++++ K+ KHRLVE++ SSTAD LGLSRAIL ND L+K+L+ L +T+ L++ L       +  F E S+    +     +VF  IGV+EPQ  ASEAF+ FA+  R ++K+ 
Sbjct:   10 EEDKLGIPTIPGKVVIQKDPQNMIGISIGGGAPLCPCLYVVQVFDNAPAAKDGTLMAGDEIVGVNGKSVKGKTKVEVAKMIQAVKGEVTMYYNKLQADPKLGKTMDIVMKKAKHRLVESMSSSTADALGLSRAILCNDGLVKKLDELERTAELYKGLMEHTKRLLKAFFELSQR---VRPAFGDVFSVIGVREPQPAASEAFVKFAEAHRSIEKFG 222
[Close]
BLAST of PRKCA-binding protein vs. Ensembl Nematostella
Match: EDO38097 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SDZ2])

HSP 1 Score: 179.874 bits (455), Expect = 5.088e-52
Identity = 80/124 (64.52%), Postives = 103/124 (83.06%), Query Frame = 3 
Query:  819 VIPDTKLTIKKYLEAKFEYLSYCLKVKEMDDEELCYVALHEALYRIETGNYEYRLLLRCRQNSRKKFSKMRNDVLEKMELLDNKHVQDIVKNLGKFMDILKQYYNDNYSAWKNAQIFPIEIDIS 1190
             IPDT+LTI+KY +AKFEYLSYCLKVKEMDDEE  Y ALHE+LYR+ETGNY+YR++LRCRQ +R+KF+K+R+DVL K+ELLD KHVQDIV  L +F+  +  Y++D Y   K A +FPIE+D++
Sbjct:  239 AIPDTRLTIRKYADAKFEYLSYCLKVKEMDDEEYAYAALHESLYRVETGNYDYRVVLRCRQLAREKFAKLRSDVLVKLELLDQKHVQDIVFQLQRFVSAVAGYHDDAYGILKEANVFPIEVDLT 362

HSP 2 Score: 170.629 bits (431), Expect = 1.218e-48
Identity = 108/243 (44.44%), Postives = 164/243 (67.49%), Query Frame = 1 
Query:  133 DKCGMRVTSGSVVLNKDKHSLXXXXXXXXXXXXXXXXXVQIFDNTVAAKDGTLEAGDEVTAIDKKSVKGVSRGEVAKWIQKAENKVTIYYNKLHLDKNQGKSVEMIFKRFKHRLVENIDSSTADFLGLSRAILVNDSLMKRLELLNQTSHLFEDLSNFISKFNEESKESAIIHKKMAEVFENIGVKEPQANASEAFLIFAKGQRCMQKYS-DF------TYAEVN----------KLTI*KYS 810
            D  G++   GSV L KDK +LIGISIGGG P CPC+Y+VQ+FDNT A+KDGTL+AGDE+  ++ KS++G ++ +VA+ IQ  + +V I Y KLH D  +GK+++++ K+ KHR+VE + SSTAD LGLSRAIL ND L+K+L+ L Q +++++ L +   ++     + +  HK++ ++F +IGV+E Q NASEAF IF++  R   ++  DF      T +++N          +LTI KY+
Sbjct:    9 DPRGLQGKPGSVTLIKDKQNLIGISIGGGAPLCPCLYVVQVFDNTPASKDGTLQAGDEIVGVNGKSLRGKTKVDVARAIQAVKEEVIINYVKLHADPKEGKTLDIVMKKMKHRMVEGMSSSTADALGLSRAILCNDGLVKKLDELEQNANVYKGLLDHARQYLHSFYQLSQTHKELGDIFASIGVRELQPNASEAFAIFSEAHRQFDRHGMDFLKKVKPTLSDLNTYLSKAIPDTRLTIRKYA 251
[Close]
BLAST of PRKCA-binding protein vs. Ensembl Medaka
Match: pick1 (protein interacting with PRKCA 1 [Source:NCBI gene;Acc:101171334])

HSP 1 Score: 188.734 bits (478), Expect = 8.510e-95
Identity = 112/212 (52.83%), Postives = 147/212 (69.34%), Query Frame = 1 
Query:  127 QEDKCGMRVTSGSVVLNKDKHSLXXXXXXXXXXXXXXXXXVQIFDNTVAAKDGTLEAGDEVTAIDKKSVKGVSRGEVAKWIQKAENKVTIYYNKLHLDKNQGKSVEMIFKRFKHRLVENIDSSTADFLGLSRAILVNDSLMKRLELLNQTSHLFEDLSNFISKFNEESKESAIIHKKMAEVFENIGVKEPQANASEAFLIFAKGQRCMQKYS 762
            +EDK G+    G+V L KD ++LIGISIGGG  YCPC+YIVQ+FDNT AA DGTL AGDE+T ++ K VKG ++ EVAK IQ  + +  I+YNKL  D  QGKS++++ K+ KHRLVEN+ + TAD LGLSRAIL ND L+KRLE L +T+ L++ L     +      E +  H+   +VF  IGV+EPQA ASEAF+ FA   R ++KY 
Sbjct:   24 EEDKLGIPTVPGTVTLKKDANNLIGISIGGGAQYCPCLYIVQVFDNTPAALDGTLAAGDEITGVNGKPVKGKTKVEVAKMIQAVQGESVIHYNKLQADPKQGKSLDIVLKKVKHRLVENLSAGTADALGLSRAILCNDGLVKRLEELEKTAELYKGLMEHTKRLLRAFFELSQTHRAFGDVFSVIGVREPQAAASEAFVKFADAHRNIEKYG 235

HSP 2 Score: 179.104 bits (453), Expect = 8.510e-95
Identity = 81/127 (63.78%), Postives = 101/127 (79.53%), Query Frame = 3 
Query:  819 VIPDTKLTIKKYLEAKFEYLSYCLKVKEMDDEELCYVALHEALYRIETGNYEYRLLLRCRQNSRKKFSKMRNDVLEKMELLDNKHVQDIVKNLGKFMDILKQYYNDNYSAWKNAQIFPIEIDISSLT 1199
             IPDTKLTI+KYL+ KFEYLSYCLKVKEMDDEE   +A+ E LYR+ TGNYEYRL+LRCRQ +R +F+KMR DVLEK+ELLD KHVQDIV  L +F+  +  YY++ Y+  + A +FPIE+D+S  T
Sbjct:  256 AIPDTKLTIRKYLDVKFEYLSYCLKVKEMDDEEYSSIAMGEPLYRVSTGNYEYRLILRCRQEARARFAKMRKDVLEKIELLDQKHVQDIVFQLQRFVSGMSHYYDECYAVLREADVFPIEVDLSRTT 382
[Close]
BLAST of PRKCA-binding protein vs. Ensembl Medaka
Match: pick1 (protein interacting with PRKCA 1 [Source:NCBI gene;Acc:101171334])

HSP 1 Score: 188.734 bits (478), Expect = 8.510e-95
Identity = 112/212 (52.83%), Postives = 147/212 (69.34%), Query Frame = 1 
Query:  127 QEDKCGMRVTSGSVVLNKDKHSLXXXXXXXXXXXXXXXXXVQIFDNTVAAKDGTLEAGDEVTAIDKKSVKGVSRGEVAKWIQKAENKVTIYYNKLHLDKNQGKSVEMIFKRFKHRLVENIDSSTADFLGLSRAILVNDSLMKRLELLNQTSHLFEDLSNFISKFNEESKESAIIHKKMAEVFENIGVKEPQANASEAFLIFAKGQRCMQKYS 762
            +EDK G+    G+V L KD ++LIGISIGGG  YCPC+YIVQ+FDNT AA DGTL AGDE+T ++ K VKG ++ EVAK IQ  + +  I+YNKL  D  QGKS++++ K+ KHRLVEN+ + TAD LGLSRAIL ND L+KRLE L +T+ L++ L     +      E +  H+   +VF  IGV+EPQA ASEAF+ FA   R ++KY 
Sbjct:   24 EEDKLGIPTVPGTVTLKKDANNLIGISIGGGAQYCPCLYIVQVFDNTPAALDGTLAAGDEITGVNGKPVKGKTKVEVAKMIQAVQGESVIHYNKLQADPKQGKSLDIVLKKVKHRLVENLSAGTADALGLSRAILCNDGLVKRLEELEKTAELYKGLMEHTKRLLRAFFELSQTHRAFGDVFSVIGVREPQAAASEAFVKFADAHRNIEKYG 235

HSP 2 Score: 179.104 bits (453), Expect = 8.510e-95
Identity = 81/127 (63.78%), Postives = 101/127 (79.53%), Query Frame = 3 
Query:  819 VIPDTKLTIKKYLEAKFEYLSYCLKVKEMDDEELCYVALHEALYRIETGNYEYRLLLRCRQNSRKKFSKMRNDVLEKMELLDNKHVQDIVKNLGKFMDILKQYYNDNYSAWKNAQIFPIEIDISSLT 1199
             IPDTKLTI+KYL+ KFEYLSYCLKVKEMDDEE   +A+ E LYR+ TGNYEYRL+LRCRQ +R +F+KMR DVLEK+ELLD KHVQDIV  L +F+  +  YY++ Y+  + A +FPIE+D+S  T
Sbjct:  256 AIPDTKLTIRKYLDVKFEYLSYCLKVKEMDDEEYSSIAMGEPLYRVSTGNYEYRLILRCRQEARARFAKMRKDVLEKIELLDQKHVQDIVFQLQRFVSGMSHYYDECYAVLREADVFPIEVDLSRTT 382
[Close]
BLAST of PRKCA-binding protein vs. Planmine SMEST
Match: SMESG000013976.1 (SMESG000013976.1)

HSP 1 Score: 467.618 bits (1202), Expect = 0.000e+0
Identity = 249/251 (99.20%), Postives = 250/251 (99.60%), Query Frame = 1 
Query:   43 MDDKSLDVKTLDPDFEVIEFEDIMNSFPQEDKCGMRVTSGSVVLNKDKHSLXXXXXXXXXXXXXXXXXVQIFDNTVAAKDGTLEAGDEVTAIDKKSVKGVSRGEVAKWIQKAENKVTIYYNKLHLDKNQGKSVEMIFKRFKHRLVENIDSSTADFLGLSRAILVNDSLMKRLELLNQTSHLFEDLSNFISKFNEESKESAIIHKKMAEVFENIGVKEPQANASEAFLIFAKGQRCMQKYSDFTYAEVNKLT 795
            MDDKSLDVKTLDPDFEVIEFEDIMNSFPQEDKCGMRVTSGSVVLNKDKHSLIGISIGGGIPYCPCIYIVQIFDNTVAAKDGTLEAGDEVTAIDKKSVKGVSRGEVAKWIQKAENKVTIYYNKLHLDKNQGKSVEMIFKRFKHRLVENIDSSTADFLGLSRAILVNDSLMKRLELLNQTSHLFEDLSNFISKFNEESKESAIIHKKMAEVFENIGVKEPQANASEAFLIFAKGQRCMQKYSDFTYAEVNK+ 
Sbjct:    1 MDDKSLDVKTLDPDFEVIEFEDIMNSFPQEDKCGMRVTSGSVVLNKDKHSLIGISIGGGIPYCPCIYIVQIFDNTVAAKDGTLEAGDEVTAIDKKSVKGVSRGEVAKWIQKAENKVTIYYNKLHLDKNQGKSVEMIFKRFKHRLVENIDSSTADFLGLSRAILVNDSLMKRLELLNQTSHLFEDLSNFISKFNEESKESAIIHKKMAEVFENIGVKEPQANASEAFLIFAKGQRCMQKYSDFTYAEVNKIV 251

HSP 2 Score: 339.347 bits (869), Expect = 0.000e+0
Identity = 165/166 (99.40%), Postives = 165/166 (99.40%), Query Frame = 3 
Query:  819 VIPDTKLTIKKYLEAKFEYLSYCLKVKEMDDEELCYVALHEALYRIETGNYEYRLLLRCRQNSRKKFSKMRNDVLEKMELLDNKHVQDIVKNLGKFMDILKQYYNDNYSAWKNAQIFPIEIDISSLTHINDEFNARLRSIQDGNQDEDDELINGDEDILQSVLKDM 1316
            VIPDTKLTIKKYLEAKFEYLSYCLKVKEMDDEE CYVALHEALYRIETGNYEYRLLLRCRQNSRKKFSKMRNDVLEKMELLDNKHVQDIVKNLGKFMDILKQYYNDNYSAWKNAQIFPIEIDISSLTHINDEFNARLRSIQDGNQDEDDELINGDEDILQSVLKDM
Sbjct:  261 VIPDTKLTIKKYLEAKFEYLSYCLKVKEMDDEESCYVALHEALYRIETGNYEYRLLLRCRQNSRKKFSKMRNDVLEKMELLDNKHVQDIVKNLGKFMDILKQYYNDNYSAWKNAQIFPIEIDISSLTHINDEFNARLRSIQDGNQDEDDELINGDEDILQSVLKDM 426
[Close]
BLAST of PRKCA-binding protein vs. Planmine SMEST
Match: SMESG000005998.1 (SMESG000005998.1)

HSP 1 Score: 200.675 bits (509), Expect = 2.425e-99
Identity = 121/220 (55.00%), Postives = 158/220 (71.82%), Query Frame = 1 
Query:  106 DIMNSFP-QEDKCGMRVTSGSVVLNKDKHSLXXXXXXXXXXXXXXXXXVQIFDNTVAAKDGTLEAGDEVTAIDKKSVKGVSRGEVAKWIQKAENKVTIYYNKLHLDKNQGKSVEMIFKRFKHRLVENIDSSTADFLGLSRAILVNDSLMKRLELLNQTSHLFEDLSNFISKFNEESKESAIIHKKMAEVFENIGVKEPQANASEAFLIFAKGQRCMQKYS 762
            D+ + +P +EDK GM VTSGSV L KD  +LIGISIGGG PYCPC+Y+VQIFDNT A+KDG+L +GDE+T ++++SVK  S+ EVA+ IQ    +VTI YNKLH D  QGK++++I K+ KHRLVE ++SSTAD LGLSRAILVND L+KRL+ +N+T  LF  L            + + +++   EVF  IGVKEPQ  ASEAF IF    R M++Y+
Sbjct:    2 DLYDDYPLEEDKMGMTVTSGSVTLLKDAQNLIGISIGGGAPYCPCLYVVQIFDNTPASKDGSLLSGDEITGVNQQSVKSKSKVEVARLIQSYRGEVTINYNKLHADPKQGKTLDIILKKVKHRLVERLESSTADALGLSRAILVNDGLVKRLDEMNKTGGLFFGLVEHSKFLVRAIYDLSKVYRAFGEVFSQIGVKEPQPRASEAFTIFGNAHRNMERYA 221

HSP 2 Score: 181.8 bits (460), Expect = 2.425e-99
Identity = 87/134 (64.93%), Postives = 105/134 (78.36%), Query Frame = 3 
Query:  819 VIPDTKLTIKKYLEAKFEYLSYCLKVKEMDDEELCYVALHEALYRIETGNYEYRLLLRCRQNSRKKFSKMRNDVLEKMELLDNKHVQDIVKNLGKFMDILKQYYNDNYSAWKNAQIFPIEIDISSLTHINDEFN 1220
             IPDT+LTIKKYL+AKFEYLSYCLKVKEMDDEE    A+ E LYR+ETGNYEYRL+LRCRQ++R +F+KMRNDVL K+ELLDNKHVQDIV  L KF+  + +Y+ D  +  K   IFPIE+D+S  T   D+ N
Sbjct:  242 AIPDTRLTIKKYLDAKFEYLSYCLKVKEMDDEEYSASAMQEPLYRVETGNYEYRLILRCRQDARIRFAKMRNDVLVKIELLDNKHVQDIVCQLDKFVKAMSKYHQDCLATMKETDIFPIEVDLSRHTFTYDKSN 375
[Close]
BLAST of PRKCA-binding protein vs. Planmine SMEST
Match: SMESG000005998.1 (SMESG000005998.1)

HSP 1 Score: 181.8 bits (460), Expect = 2.591e-92
Identity = 87/134 (64.93%), Postives = 105/134 (78.36%), Query Frame = 3 
Query:  819 VIPDTKLTIKKYLEAKFEYLSYCLKVKEMDDEELCYVALHEALYRIETGNYEYRLLLRCRQNSRKKFSKMRNDVLEKMELLDNKHVQDIVKNLGKFMDILKQYYNDNYSAWKNAQIFPIEIDISSLTHINDEFN 1220
             IPDT+LTIKKYL+AKFEYLSYCLKVKEMDDEE    A+ E LYR+ETGNYEYRL+LRCRQ++R +F+KMRNDVL K+ELLDNKHVQDIV  L KF+  + +Y+ D  +  K   IFPIE+D+S  T   D+ N
Sbjct:  287 AIPDTRLTIKKYLDAKFEYLSYCLKVKEMDDEEYSASAMQEPLYRVETGNYEYRLILRCRQDARIRFAKMRNDVLVKIELLDNKHVQDIVCQLDKFVKAMSKYHQDCLATMKETDIFPIEVDLSRHTFTYDKSN 420

HSP 2 Score: 177.178 bits (448), Expect = 2.591e-92
Identity = 120/265 (45.28%), Postives = 158/265 (59.62%), Query Frame = 1 
Query:  106 DIMNSFP-QEDKCGMRVTSGSVVLNKDKHSLXXXXXXXXXXXXXXXXXVQIFDNTVAAKDGTLEAGDEVTAIDKKSVKGVSRGEVAKWIQKAENKVTIYYNKLHLDKNQGKSVEMIFKRFKHRLVENIDSSTADFLGLSRAILVN---------------------------------------------DSLMKRLELLNQTSHLFEDLSNFISKFNEESKESAIIHKKMAEVFENIGVKEPQANASEAFLIFAKGQRCMQKYS 762
            D+ + +P +EDK GM VTSGSV L KD  +LIGISIGGG PYCPC+Y+VQIFDNT A+KDG+L +GDE+T ++++SVK  S+ EVA+ IQ    +VTI YNKLH D  QGK++++I K+ KHRLVE ++SSTAD LGLSRAILVN                                             + L+KRL+ +N+T  LF  L            + + +++   EVF  IGVKEPQ  ASEAF IF    R M++Y+
Sbjct:    2 DLYDDYPLEEDKMGMTVTSGSVTLLKDAQNLIGISIGGGAPYCPCLYVVQIFDNTPASKDGSLLSGDEITGVNQQSVKSKSKVEVARLIQSYRGEVTINYNKLHADPKQGKTLDIILKKVKHRLVERLESSTADALGLSRAILVNVLKKVKHRVVENMTSSTADAFGLSRAILCNVLSIENCSSMSSKNVNGLVKRLDEMNKTGGLFFGLVEHSKFLVRAIYDLSKVYRAFGEVFSQIGVKEPQPRASEAFTIFGNAHRNMERYA 266
[Close]
BLAST of PRKCA-binding protein vs. Planmine SMEST
Match: SMESG000005998.1 (SMESG000005998.1)

HSP 1 Score: 181.415 bits (459), Expect = 1.427e-88
Identity = 87/134 (64.93%), Postives = 105/134 (78.36%), Query Frame = 3 
Query:  819 VIPDTKLTIKKYLEAKFEYLSYCLKVKEMDDEELCYVALHEALYRIETGNYEYRLLLRCRQNSRKKFSKMRNDVLEKMELLDNKHVQDIVKNLGKFMDILKQYYNDNYSAWKNAQIFPIEIDISSLTHINDEFN 1220
             IPDT+LTIKKYL+AKFEYLSYCLKVKEMDDEE    A+ E LYR+ETGNYEYRL+LRCRQ++R +F+KMRNDVL K+ELLDNKHVQDIV  L KF+  + +Y+ D  +  K   IFPIE+D+S  T   D+ N
Sbjct:  307 AIPDTRLTIKKYLDAKFEYLSYCLKVKEMDDEEYSASAMQEPLYRVETGNYEYRLILRCRQDARIRFAKMRNDVLVKIELLDNKHVQDIVCQLDKFVKAMSKYHQDCLATMKETDIFPIEVDLSRHTFTYDKSN 440

HSP 2 Score: 165.236 bits (417), Expect = 1.427e-88
Identity = 120/285 (42.11%), Postives = 156/285 (54.74%), Query Frame = 1 
Query:  106 DIMNSFP-QEDKCGMRVTSGSVVLNKDKHSLXXXXXXXXXXXXXXXXXVQIFDNTVAAKDGTLEAGDEVTAIDKKSVKGVSRGEVAKWIQKAENKVTIYYNKLHLDKNQGKSVEMIFKRFKHRLVE------------------------------NIDSSTADFLGLSRAILVN-----------------------------------DSLMKRLELLNQTSHLFEDLSNFISKFNEESKESAIIHKKMAEVFENIGVKEPQANASEAFLIFAKGQRCMQKYS 762
            D+ + +P +EDK GM VTSGSV L KD  +LIGISIGGG PYCPC+Y+VQIFDNT A+KDG+L +GDE+T ++++SVK  S+ EVA+ IQ    +VTI YNKLH D  QGK++++I K+ KHRLVE                              N+ SSTAD  GLSRAIL N                                   D L+KRL+ +N+T  LF  L            + + +++   EVF  IGVKEPQ  ASEAF IF    R M++Y+
Sbjct:    2 DLYDDYPLEEDKMGMTVTSGSVTLLKDAQNLIGISIGGGAPYCPCLYVVQIFDNTPASKDGSLLSGDEITGVNQQSVKSKSKVEVARLIQSYRGEVTINYNKLHADPKQGKTLDIILKKVKHRLVERLESSTADALGLSRAILVNVLKKVKHRVVENMTSSTADAFGLSRAILCNVLSIENCSSMSSKNVTCLRLYKFWDLFLLINDTHLDGLVKRLDEMNKTGGLFFGLVEHSKFLVRAIYDLSKVYRAFGEVFSQIGVKEPQPRASEAFTIFGNAHRNMERYA 286
[Close]
BLAST of PRKCA-binding protein vs. Planmine SMEST
Match: SMESG000050775.1 (SMESG000050775.1)

HSP 1 Score: 175.252 bits (443), Expect = 2.582e-85
Identity = 102/215 (47.44%), Postives = 154/215 (71.63%), Query Frame = 1 
Query:  112 MNSFPQEDKCGMRVTSGSVVLNKDKHSLXXXXXXXXXXXXXXXXXVQIFDNTVAAKDGTLEAGDEVTAIDKKSVKGVSRGEVAKWIQKAENKVTIYYNKLHLDKNQGKSVEMIFKRFKHRLVENIDSSTADFLGLSRAILVNDSLMKRLELLNQTSHLFEDLSNFISKFNEESKESAIIHKKMAEVFENIGVKEPQANASEAFLIFAKGQRCMQK 756
            MN F +    GMR+TSGSV L K +++LIGISIGGG P CP +Y+VQ+FDN+ +AKDGTLEAGDE+ +++  SVK  +R E AK IQ++++ VTI YNKLH+D   GKS ++  K+ KH+ V+ I+SS AD +G+SRAILVND+++K+   L +T++++++L  ++S F   + E  ++HK   ++   IG++E Q +A+EAF  F K  + M+K
Sbjct:    1 MNVFDENIPKGMRITSGSVTLEKKRNNLIGISIGGGAPLCPALYVVQVFDNSSSAKDGTLEAGDELVSVNGISVKNYTRTETAKLIQESKDSVTINYNKLHVDCIHGKSCDINLKKIKHKFVDKINSSVADLIGMSRAILVNDTMVKKFSNLKETANVYKNLVKYLSNFLHANLEMGLVHKVFGDLNIEIGIRELQVSANEAFCKFGKIHQTMEK 215

HSP 2 Score: 160.229 bits (404), Expect = 2.582e-85
Identity = 73/127 (57.48%), Postives = 99/127 (77.95%), Query Frame = 3 
Query:  819 VIPDTKLTIKKYLEAKFEYLSYCLKVKEMDDEELCYVALHEALYRIETGNYEYRLLLRCRQNSRKKFSKMRNDVLEKMELLDNKHVQDIVKNLGKFMDILKQYYNDNYSAWKNAQIFPIEIDISSLT 1199
             IPD  LTIKKYL+ KFEYL+YCLK+KEMDDEE  + ++HE+LYR+ETGNYEYR  LRCRQ +R++F++ R +VL K++LLDNK+VQDI  NL   +  L ++++ N+   KN ++FPIEIDI+  T
Sbjct:  238 AIPDIYLTIKKYLDVKFEYLAYCLKIKEMDDEEYGFYSMHESLYRLETGNYEYRFNLRCRQEARRRFAQERTNVLIKLDLLDNKYVQDITTNLQTLVQCLSEFHSANFHLLKNIRLFPIEIDIAHTT 364
The following BLAST results are available for this feature:
BLAST of PRKCA-binding protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
PICK11.819e-9551.85protein interacting with PRKCA 1 [Source:HGNC Symb... [more]
PICK11.819e-9551.85protein interacting with PRKCA 1 [Source:HGNC Symb... [more]
PICK11.626e-5651.85protein interacting with PRKCA 1 [Source:HGNC Symb... [more]
PICK11.913e-3056.80protein interacting with PRKCA 1 [Source:HGNC Symb... [more]
PICK11.338e-2156.07protein interacting with PRKCA 1 [Source:HGNC Symb... [more]
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BLAST of PRKCA-binding protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 1
Match NameE-valueIdentityDescription
Y57G11C.224.575e-6857.14pep chromosome:WBcel235:IV:14837112:14853662:1 gen... [more]
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BLAST of PRKCA-binding protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
PICK16.888e-8350.47gene:FBgn0032447 transcript:FBtr0080395[more]
PICK15.532e-8250.00gene:FBgn0032447 transcript:FBtr0340543[more]
PICK12.858e-8050.00gene:FBgn0032447 transcript:FBtr0340542[more]
PICK12.858e-8050.00gene:FBgn0032447 transcript:FBtr0340544[more]
PICK12.858e-8050.00gene:FBgn0032447 transcript:FBtr0080396[more]
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BLAST of PRKCA-binding protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 1
Match NameE-valueIdentityDescription
pick13.157e-9653.30protein interacting with prkca 1 [Source:ZFIN;Acc:... [more]
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BLAST of PRKCA-binding protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 4
Match NameE-valueIdentityDescription
pick11.673e-9250.23protein interacting with PRKCA 1 [Source:NCBI gene... [more]
pick11.858e-9050.72protein interacting with PRKCA 1 [Source:NCBI gene... [more]
pick12.486e-9050.72protein interacting with PRKCA 1 [Source:NCBI gene... [more]
pick11.220e-5150.72protein interacting with PRKCA 1 [Source:NCBI gene... [more]
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BLAST of PRKCA-binding protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 4
Match NameE-valueIdentityDescription
Pick11.623e-9652.31protein interacting with C kinase 1 [Source:MGI Sy... [more]
Pick11.623e-9652.31protein interacting with C kinase 1 [Source:MGI Sy... [more]
Pick11.623e-9652.31protein interacting with C kinase 1 [Source:MGI Sy... [more]
Gm494867.763e-8452.31predicted gene, 49486 [Source:MGI Symbol;Acc:MGI:6... [more]
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BLAST of PRKCA-binding protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q2T9M1|PICK1_BOVIN1.221e-9551.85PRKCA-binding protein OS=Bos taurus OX=9913 GN=PIC... [more]
sp|Q9EP80|PICK1_RAT1.372e-9551.85PRKCA-binding protein OS=Rattus norvegicus OX=1011... [more]
sp|Q5REH1|PICK1_PONAB7.535e-9551.85PRKCA-binding protein OS=Pongo abelii OX=9601 GN=P... [more]
sp|Q9NRD5|PICK1_HUMAN7.920e-9551.85PRKCA-binding protein OS=Homo sapiens OX=9606 GN=P... [more]
sp|Q62083|PICK1_MOUSE1.077e-9452.31PRKCA-binding protein OS=Mus musculus OX=10090 GN=... [more]
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BLAST of PRKCA-binding protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A210QSU71.253e-9655.19PRKCA-binding protein OS=Mizuhopecten yessoensis O... [more]
A0A0B7AE741.607e-9553.02Uncharacterized protein OS=Arion vulgaris OX=10286... [more]
I6YMZ02.415e-9552.04PICK1 OS=Aplysia californica OX=6500 PE=2 SV=1[more]
A0A3S0ZXP01.315e-9450.21Uncharacterized protein OS=Elysia chlorotica OX=18... [more]
A0A5J5N5492.113e-9466.93Uncharacterized protein OS=Muntiacus reevesi OX=98... [more]
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BLAST of PRKCA-binding protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 2
Match NameE-valueIdentityDescription
pick13.109e-9652.49protein interacting with PRKCA 1 [Source:NCBI gene... [more]
pick13.109e-9652.49protein interacting with PRKCA 1 [Source:NCBI gene... [more]
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BLAST of PRKCA-binding protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1
Match NameE-valueIdentityDescription
pick12.571e-5450.00protein interacting with prkca 1 [Source:ZFIN;Acc:... [more]
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BLAST of PRKCA-binding protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of PRKCA-binding protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1
Match NameE-valueIdentityDescription
EDO380975.088e-5264.52Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of PRKCA-binding protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 2
Match NameE-valueIdentityDescription
pick18.510e-9552.83protein interacting with PRKCA 1 [Source:NCBI gene... [more]
pick18.510e-9552.83protein interacting with PRKCA 1 [Source:NCBI gene... [more]
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BLAST of PRKCA-binding protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000013976.10.000e+099.20SMESG000013976.1[more]
SMESG000005998.12.425e-9955.00SMESG000005998.1[more]
SMESG000005998.12.591e-9264.93SMESG000005998.1[more]
SMESG000005998.11.427e-8864.93SMESG000005998.1[more]
SMESG000050775.12.582e-8547.44SMESG000050775.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30017874 ID=SMED30017874|Name=PRKCA-binding protein|organism=Schmidtea mediterranea sexual|type=transcript|length=1442bp
TATTGTTATTTGTTTTAAATATAAATATTTTAATTATTTATTATGGATGA
TAAATCATTGGATGTGAAAACATTGGATCCAGATTTTGAAGTGATCGAAT
TTGAAGATATTATGAACAGTTTTCCTCAAGAAGATAAATGTGGTATGCGA
GTTACAAGCGGATCAGTAGTTTTAAATAAGGACAAACATAGCCTTATTGG
AATTAGTATTGGTGGAGGAATTCCGTACTGCCCTTGCATTTATATTGTAC
AAATTTTCGATAATACAGTAGCCGCTAAGGACGGTACACTGGAAGCTGGA
GACGAAGTTACCGCAATTGACAAAAAATCTGTAAAAGGTGTAAGCCGAGG
CGAAGTAGCCAAATGGATTCAAAAAGCAGAGAACAAAGTCACCATTTATT
ATAATAAGTTGCACCTGGACAAAAATCAAGGAAAATCCGTGGAAATGATT
TTCAAGAGGTTCAAACACAGATTAGTAGAAAATATAGATTCATCAACAGC
AGATTTTTTGGGCCTCAGTAGAGCCATTTTGGTCAATGATTCTTTGATGA
AAAGATTAGAATTACTTAATCAAACTTCACATTTATTTGAAGATCTTTCT
AATTTTATATCAAAATTTAATGAAGAGAGCAAAGAATCTGCTATAATTCA
TAAAAAAATGGCAGAAGTTTTTGAAAACATTGGAGTCAAAGAACCACAGG
CTAATGCTAGTGAAGCATTCTTGATTTTTGCGAAAGGCCAACGATGCATG
CAAAAGTATTCAGATTTTACCTATGCTGAAGTAAATAAATTGACGATTTG
AAAATATTCTTGAAAAAGGTAATTCCAGACACAAAACTTACTATTAAAAA
ATACTTAGAAGCTAAATTCGAGTATTTATCTTATTGCCTAAAAGTCAAAG
AAATGGACGACGAAGAATTATGTTATGTGGCATTGCACGAAGCTTTATAT
CGTATAGAAACTGGAAATTATGAATATCGGTTGCTTTTAAGATGTCGTCA
AAATAGTAGAAAAAAATTTTCAAAAATGAGAAATGATGTTTTAGAAAAAA
TGGAATTGCTTGACAACAAACATGTTCAAGATATAGTGAAAAATTTAGGA
AAATTTATGGATATTCTGAAACAGTATTACAATGATAATTACTCTGCTTG
GAAAAATGCTCAAATTTTTCCCATAGAAATAGACATAAGCAGTCTAACTC
ATATTAATGATGAATTTAATGCGAGACTTAGAAGCATCCAAGATGGTAAT
CAAGACGAGGATGACGAACTTATCAATGGCGACGAAGATATATTGCAATC
TGTATTAAAGGATATGTGAACTTGACGTGTGTCAAATCTGTTGTATTTGT
GAATATTATTTTTGACAATTTTTTGTTTGGCTTCTCAATTTAGTTTCTAG
GTTTAAATTAAGTTCTTTTAAGTTCTTCAATATCAAAGGATT
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protein sequence of SMED30017874-orf-1

>SMED30017874-orf-1 ID=SMED30017874-orf-1|Name=SMED30017874-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=139bp
MDDEELCYVALHEALYRIETGNYEYRLLLRCRQNSRKKFSKMRNDVLEKM
ELLDNKHVQDIVKNLGKFMDILKQYYNDNYSAWKNAQIFPIEIDISSLTH
INDEFNARLRSIQDGNQDEDDELINGDEDILQSVLKDM*
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protein sequence of SMED30017874-orf-2

>SMED30017874-orf-2 ID=SMED30017874-orf-2|Name=SMED30017874-orf-2|organism=Schmidtea mediterranea sexual|type=polypeptide|length=253bp
MDDKSLDVKTLDPDFEVIEFEDIMNSFPQEDKCGMRVTSGSVVLNKDKHS
LIGISIGGGIPYCPCIYIVQIFDNTVAAKDGTLEAGDEVTAIDKKSVKGV
SRGEVAKWIQKAENKVTIYYNKLHLDKNQGKSVEMIFKRFKHRLVENIDS
STADFLGLSRAILVNDSLMKRLELLNQTSHLFEDLSNFISKFNEESKESA
IIHKKMAEVFENIGVKEPQANASEAFLIFAKGQRCMQKYSDFTYAEVNKL
TI*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000016pharynx
PLANA:0002032epidermal cell
Vocabulary: INTERPRO
TermDefinition
IPR036034PDZ_sf
IPR030798Arfaptin_fam
IPR001478PDZ
IPR010504AH_dom
IPR027267AH/BAR_dom_sf
Vocabulary: molecular function
TermDefinition
GO:0005515protein binding
GO:0019904protein domain specific binding
GO:0001664G-protein coupled receptor binding
GO:0003779actin binding
GO:0005080protein kinase C binding
GO:0005102signaling receptor binding
GO:0008022protein C-terminus binding
GO:0008092cytoskeletal protein binding
GO:0016887ATPase activity
GO:0030971receptor tyrosine kinase binding
GO:0035256G-protein coupled glutamate receptor binding
GO:0042802identical protein binding
GO:0046872metal ion binding
GO:0046875ephrin receptor binding
GO:0051015actin filament binding
GO:0051020GTPase binding
GO:0071933Arp2/3 complex binding
Vocabulary: biological process
TermDefinition
GO:0002092positive regulation of receptor internalization
GO:0006468protein phosphorylation
GO:0007205protein kinase C-activating G-protein coupled receptor signaling pathway
GO:0010629negative regulation of gene expression
GO:0015844monoamine transport
GO:0015872dopamine transport
GO:0021782glial cell development
GO:0034316negative regulation of Arp2/3 complex-mediated actin nucleation
GO:0036294cellular response to decreased oxygen levels
GO:0042149cellular response to glucose starvation
GO:0043113receptor clustering
GO:0050900leukocyte migration
GO:0060292long term synaptic depression
GO:0060548negative regulation of cell death
GO:0097061dendritic spine organization
GO:0097062dendritic spine maintenance
Vocabulary: cellular component
TermDefinition
GO:0005737cytoplasm
GO:0005794Golgi apparatus
GO:0005856cytoskeleton
GO:0005886plasma membrane
GO:0008021synaptic vesicle
GO:0014069postsynaptic density
GO:0016020membrane
GO:0030054cell junction
GO:0030425dendrite
GO:0042734presynaptic membrane
GO:0043005neuron projection
GO:0043234protein complex
GO:0045202synapse
GO:0045211postsynaptic membrane
GO:0048471perinuclear region of cytoplasm
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR001478PDZ domainSMARTSM00228pdz_newcoord: 50..122
e-value: 1.0E-9
score: 48.3
IPR001478PDZ domainPFAMPF00595PDZcoord: 42..118
e-value: 3.9E-8
score: 33.5
IPR001478PDZ domainPROSITEPS50106PDZcoord: 41..124
score: 15.139
IPR036034PDZ superfamilyGENE3DG3DSA:2.30.42.10coord: 34..145
e-value: 9.0E-30
score: 104.6
IPR036034PDZ superfamilySUPERFAMILYSSF50156PDZ domain-likecoord: 41..119
IPR027267AH/BAR domain superfamilyGENE3DG3DSA:1.20.1270.60coord: 164..251
e-value: 7.0E-6
score: 27.8
IPR027267AH/BAR domain superfamilySUPERFAMILYSSF103657BAR/IMD domain-likecoord: 161..250
IPR010504Arfaptin homology (AH) domainPFAMPF06456Arfaptincoord: 138..249
e-value: 7.9E-16
score: 58.3
NoneNo IPR availablePANTHERPTHR12141:SF1PRKCA-BINDING PROTEINcoord: 26..240
NoneNo IPR availableCDDcd00992PDZ_signalingcoord: 62..118
e-value: 7.47733E-9
score: 49.4875
IPR030798Arfaptin familyPANTHERPTHR12141ARFAPTIN-RELATEDADP-RIBOSYLATION FACTOR INTERACTING PROTEIN/PROTEIN KINASE C ALPHA BINDING PROTEINcoord: 26..240