nuclear factor Y complex A

Overview


Name	nuclear factor Y complex A (AKG62116.1)
Smed ID	SMED30017865
Length (bp)	1091

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of nuclear factor Y complex A (SMED30017865) t-SNE clustered cells

Violin plots show distribution of expression levels for nuclear factor Y complex A (SMED30017865) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of nuclear factor Y complex A (SMED30017865) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for nuclear factor Y complex A (SMED30017865) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30017865

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 6

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
testis	SMED30017865	h1SMcG0002214	KU366701	smed_ncbi_20240424	PMID:27304889 Iyer et al., 2016
X2 cell	SMED30017865	h1SMcG0002214	SmedASXL_004386	SmedAsxl_ww_GCZZ01	PMID:26114597 Zhu et al., 2015
nervous system	SMED30017865	h1SMcG0002214	dd_Smed_v4_4860_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parenchymal cell	SMED30017865	h1SMcG0002214	dd_Smed_v4_4860_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30017865	h1SMcG0000753	Contig5045	GPL15192	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30017865	h1SMcG0002214	Contig5045	GPL15192	PMID:29674431 Fincher et al., 2018

Note: Hover over icons to view figure legend

Homology

[Close]

BLAST of nuclear factor Y complex A vs. Ensembl Human
Match: NFYA (nuclear transcription factor Y subunit alpha [Source:HGNC Symbol;Acc:HGNC:7804])

HSP 1 Score: 107.842 bits (268), Expect = 3.724e-26
Identity = 47/60 (78.33%), Postives = 54/60 (90.00%), Query Frame = 3

Query:  531 PLYVNAKQYNRILKRRQARAKLEAQGRLPKGRSKYLHESRHKHAMNRVRGEGGKFCSIKK 710
            PLYVNAKQY+RILKRRQARAKLEA+G++PK R KYLHESRH+HAM R RGEGG+F S K+
Sbjct:  235 PLYVNAKQYHRILKRRQARAKLEAEGKIPKERRKYLHESRHRHAMARKRGEGGRFFSPKE 294

[Close]

BLAST of nuclear factor Y complex A vs. Ensembl Human
Match: NFYA (nuclear transcription factor Y subunit alpha [Source:HGNC Symbol;Acc:HGNC:7804])

HSP 1 Score: 108.612 bits (270), Expect = 3.915e-26
Identity = 47/60 (78.33%), Postives = 54/60 (90.00%), Query Frame = 3

Query:  531 PLYVNAKQYNRILKRRQARAKLEAQGRLPKGRSKYLHESRHKHAMNRVRGEGGKFCSIKK 710
            PLYVNAKQY+RILKRRQARAKLEA+G++PK R KYLHESRH+HAM R RGEGG+F S K+
Sbjct:  264 PLYVNAKQYHRILKRRQARAKLEAEGKIPKERRKYLHESRHRHAMARKRGEGGRFFSPKE 323

[Close]

BLAST of nuclear factor Y complex A vs. Ensembl Celegans
Match: nfya-1 (Nuclear transcription Factor Y, A (Alpha) subunit [Source:UniProtKB/TrEMBL;Acc:G5EEG1])

HSP 1 Score: 81.6481 bits (200), Expect = 8.557e-17
Identity = 35/59 (59.32%), Postives = 44/59 (74.58%), Query Frame = 3

Query:  531 PLYVNAKQYNRILKRRQARAKLEAQGRLPKGRSKYLHESRHKHAMNRVRGEGGKFCSIK 707
            P+ VN KQ+NRI++RR+ R +LEA GRLP  R KYLHESRH HA+ R RG  G+F + K
Sbjct:  304 PMLVNPKQFNRIMRRREMRQQLEASGRLPLARQKYLHESRHLHALKRKRGLDGRFDNTK 362

[Close]

BLAST of nuclear factor Y complex A vs. Ensembl Celegans
Match: nfya-2 (Nuclear transcription Factor Y, A (Alpha) subunit [Source:UniProtKB/TrEMBL;Acc:F3Y5S3])

HSP 1 Score: 68.9366 bits (167), Expect = 4.552e-13
Identity = 31/55 (56.36%), Postives = 40/55 (72.73%), Query Frame = 3

Query:  531 PLYVNAKQYNRILKRRQARAKLEAQGRLPKGRSKYLHESRHKHAMNRVRGEGGKF 695
            P+ VN +QY RI+KRR+ R K+E  GRLP  R KY+HESR +HA+ R R  GG+F
Sbjct:  139 PIMVNPRQYKRIIKRREMRQKMEDSGRLPLERQKYMHESRRQHALKRRRT-GGRF 192

[Close]

BLAST of nuclear factor Y complex A vs. Ensembl Celegans
Match: nfya-2 (Nuclear transcription Factor Y, A (Alpha) subunit [Source:UniProtKB/TrEMBL;Acc:F3Y5S3])

HSP 1 Score: 68.5514 bits (166), Expect = 6.103e-13
Identity = 31/55 (56.36%), Postives = 40/55 (72.73%), Query Frame = 3

Query:  531 PLYVNAKQYNRILKRRQARAKLEAQGRLPKGRSKYLHESRHKHAMNRVRGEGGKF 695
            P+ VN +QY RI+KRR+ R K+E  GRLP  R KY+HESR +HA+ R R  GG+F
Sbjct:  148 PIMVNPRQYKRIIKRREMRQKMEDSGRLPLERQKYMHESRRQHALKRRRT-GGRF 201

[Close]

BLAST of nuclear factor Y complex A vs. Ensembl Celegans
Match: nfya-2 (Nuclear transcription Factor Y, A (Alpha) subunit [Source:UniProtKB/TrEMBL;Acc:F3Y5S3])

HSP 1 Score: 64.6994 bits (156), Expect = 1.319e-12
Identity = 30/52 (57.69%), Postives = 38/52 (73.08%), Query Frame = 3

Query:  540 VNAKQYNRILKRRQARAKLEAQGRLPKGRSKYLHESRHKHAMNRVRGEGGKF 695
            VN +QY RI+KRR+ R K+E  GRLP  R KY+HESR +HA+ R R  GG+F
Sbjct:    2 VNPRQYKRIIKRREMRQKMEDSGRLPLERQKYMHESRRQHALKRRRT-GGRF 52

[Close]

BLAST of nuclear factor Y complex A vs. Ensembl Fly
Match: Nf-YA (gene:FBgn0035993 transcript:FBtr0076504)

HSP 1 Score: 97.8265 bits (242), Expect = 2.189e-22
Identity = 45/60 (75.00%), Postives = 51/60 (85.00%), Query Frame = 3

Query:  531 PLYVNAKQYNRILKRRQARAKLEAQGRLPKGRSKYLHESRHKHAMNRVRGEGGKFCSIKK 710
            PLYVNAKQY RIL RRQARAKLE+  R+PK R KYLHESRH+HAMNR RGEGG+F S ++
Sbjct:  290 PLYVNAKQYKRILIRRQARAKLES--RIPKERCKYLHESRHRHAMNRARGEGGRFHSAQE 347

[Close]

BLAST of nuclear factor Y complex A vs. Ensembl Zebrafish
Match: nfyal (nuclear transcription factor Y, alpha, like [Source:ZFIN;Acc:ZDB-GENE-040718-491])

HSP 1 Score: 108.227 bits (269), Expect = 2.918e-26
Identity = 47/63 (74.60%), Postives = 55/63 (87.30%), Query Frame = 3

Query:  531 PLYVNAKQYNRILKRRQARAKLEAQGRLPKGRSKYLHESRHKHAMNRVRGEGGKFCSIKKTSK 719
            PLYVNAKQY+RILKRRQARAKLEA+G++PK R KYLHESRHKHAM R RG+GG+F S K+  +
Sbjct:  236 PLYVNAKQYHRILKRRQARAKLEAEGKIPKERKKYLHESRHKHAMQRKRGDGGRFFSPKEKEE 298

[Close]

BLAST of nuclear factor Y complex A vs. Ensembl Zebrafish
Match: nfyal (nuclear transcription factor Y, alpha, like [Source:ZFIN;Acc:ZDB-GENE-040718-491])

HSP 1 Score: 108.612 bits (270), Expect = 4.360e-26
Identity = 47/63 (74.60%), Postives = 55/63 (87.30%), Query Frame = 3

Query:  531 PLYVNAKQYNRILKRRQARAKLEAQGRLPKGRSKYLHESRHKHAMNRVRGEGGKFCSIKKTSK 719
            PLYVNAKQY+RILKRRQARAKLEA+G++PK R KYLHESRHKHAM R RG+GG+F S K+  +
Sbjct:  299 PLYVNAKQYHRILKRRQARAKLEAEGKIPKERKKYLHESRHKHAMQRKRGDGGRFFSPKEKEE 361

[Close]

BLAST of nuclear factor Y complex A vs. Ensembl Zebrafish
Match: nfya (nuclear transcription factor Y, alpha [Source:ZFIN;Acc:ZDB-GENE-010501-1])

HSP 1 Score: 104.76 bits (260), Expect = 4.621e-26
Identity = 46/63 (73.02%), Postives = 55/63 (87.30%), Query Frame = 3

Query:  531 PLYVNAKQYNRILKRRQARAKLEAQGRLPKGRSKYLHESRHKHAMNRVRGEGGKFCSIKKTSK 719
            PLYVNAKQY+RILKRRQARAKLEA+G++PK R KYLHESRH+HAM R RG+GG+F S K+  +
Sbjct:  130 PLYVNAKQYHRILKRRQARAKLEAEGKIPKERRKYLHESRHRHAMARKRGDGGRFFSPKEKEE 192

[Close]

BLAST of nuclear factor Y complex A vs. Ensembl Zebrafish
Match: nfya (nuclear transcription factor Y, alpha [Source:ZFIN;Acc:ZDB-GENE-010501-1])

HSP 1 Score: 106.686 bits (265), Expect = 1.117e-25
Identity = 46/63 (73.02%), Postives = 55/63 (87.30%), Query Frame = 3

Query:  531 PLYVNAKQYNRILKRRQARAKLEAQGRLPKGRSKYLHESRHKHAMNRVRGEGGKFCSIKKTSK 719
            PLYVNAKQY+RILKRRQARAKLEA+G++PK R KYLHESRH+HAM R RG+GG+F S K+  +
Sbjct:  257 PLYVNAKQYHRILKRRQARAKLEAEGKIPKERRKYLHESRHRHAMARKRGDGGRFFSPKEKEE 319

[Close]

BLAST of nuclear factor Y complex A vs. Ensembl Zebrafish
Match: nfya (nuclear transcription factor Y, alpha [Source:ZFIN;Acc:ZDB-GENE-010501-1])

HSP 1 Score: 106.301 bits (264), Expect = 1.223e-25
Identity = 46/63 (73.02%), Postives = 55/63 (87.30%), Query Frame = 3

Query:  531 PLYVNAKQYNRILKRRQARAKLEAQGRLPKGRSKYLHESRHKHAMNRVRGEGGKFCSIKKTSK 719
            PLYVNAKQY+RILKRRQARAKLEA+G++PK R KYLHESRH+HAM R RG+GG+F S K+  +
Sbjct:  232 PLYVNAKQYHRILKRRQARAKLEAEGKIPKERRKYLHESRHRHAMARKRGDGGRFFSPKEKEE 294

[Close]

BLAST of nuclear factor Y complex A vs. Ensembl Xenopus
Match: nfya (nuclear transcription factor Y subunit alpha [Source:NCBI gene;Acc:394530])

HSP 1 Score: 106.686 bits (265), Expect = 1.180e-25
Identity = 46/66 (69.70%), Postives = 56/66 (84.85%), Query Frame = 3

Query:  531 PLYVNAKQYNRILKRRQARAKLEAQGRLPKGRSKYLHESRHKHAMNRVRGEGGKFCSIKKTSKNEI 728
            PLYVNAKQY+RILKRRQARAKLEA+G++PK R KYLHESRH+HAM R RG+GG+F S K+   + +
Sbjct:  255 PLYVNAKQYHRILKRRQARAKLEAEGKIPKERRKYLHESRHRHAMARKRGDGGRFFSPKEKESHHL 320

[Close]

BLAST of nuclear factor Y complex A vs. Ensembl Xenopus
Match: nfya (nuclear transcription factor Y subunit alpha [Source:NCBI gene;Acc:394530])

HSP 1 Score: 105.916 bits (263), Expect = 1.253e-25
Identity = 46/66 (69.70%), Postives = 56/66 (84.85%), Query Frame = 3

Query:  531 PLYVNAKQYNRILKRRQARAKLEAQGRLPKGRSKYLHESRHKHAMNRVRGEGGKFCSIKKTSKNEI 728
            PLYVNAKQY+RILKRRQARAKLEA+G++PK R KYLHESRH+HAM R RG+GG+F S K+   + +
Sbjct:  227 PLYVNAKQYHRILKRRQARAKLEAEGKIPKERRKYLHESRHRHAMARKRGDGGRFFSPKEKESHHL 292

[Close]

BLAST of nuclear factor Y complex A vs. Ensembl Mouse
Match: Nfya (nuclear transcription factor-Y alpha [Source:MGI Symbol;Acc:MGI:97316])

HSP 1 Score: 106.686 bits (265), Expect = 7.345e-27
Identity = 47/60 (78.33%), Postives = 54/60 (90.00%), Query Frame = 3

Query:  531 PLYVNAKQYNRILKRRQARAKLEAQGRLPKGRSKYLHESRHKHAMNRVRGEGGKFCSIKK 710
            PLYVNAKQY+RILKRRQARAKLEA+G++PK R KYLHESRH+HAM R RGEGG+F S K+
Sbjct:  128 PLYVNAKQYHRILKRRQARAKLEAEGKIPKERRKYLHESRHRHAMARKRGEGGRFFSPKE 187

[Close]

Query:  531 PLYVNAKQYNRILKRRQARAKLEAQGRLPKGRSKYLHESRHKHAMNRVRGEGGKFCSIKK 710
            PLYVNAKQY+RILKRRQARAKLEA+G++PK R KYLHESRH+HAM R RGEGG+F S K+
Sbjct:  128 PLYVNAKQYHRILKRRQARAKLEAEGKIPKERRKYLHESRHRHAMARKRGEGGRFFSPKE 187

[Close]

BLAST of nuclear factor Y complex A vs. Ensembl Mouse
Match: Nfya (nuclear transcription factor-Y alpha [Source:MGI Symbol;Acc:MGI:97316])

HSP 1 Score: 108.612 bits (270), Expect = 2.517e-26
Identity = 47/60 (78.33%), Postives = 54/60 (90.00%), Query Frame = 3

Query:  531 PLYVNAKQYNRILKRRQARAKLEAQGRLPKGRSKYLHESRHKHAMNRVRGEGGKFCSIKK 710
            PLYVNAKQY+RILKRRQARAKLEA+G++PK R KYLHESRH+HAM R RGEGG+F S K+
Sbjct:  263 PLYVNAKQYHRILKRRQARAKLEAEGKIPKERRKYLHESRHRHAMARKRGEGGRFFSPKE 322

[Close]

Query:  531 PLYVNAKQYNRILKRRQARAKLEAQGRLPKGRSKYLHESRHKHAMNRVRGEGGKFCSIKK 710
            PLYVNAKQY+RILKRRQARAKLEA+G++PK R KYLHESRH+HAM R RGEGG+F S K+
Sbjct:  263 PLYVNAKQYHRILKRRQARAKLEAEGKIPKERRKYLHESRHRHAMARKRGEGGRFFSPKE 322

[Close]

BLAST of nuclear factor Y complex A vs. Ensembl Mouse
Match: Nfya (nuclear transcription factor-Y alpha [Source:MGI Symbol;Acc:MGI:97316])

HSP 1 Score: 108.612 bits (270), Expect = 2.557e-26
Identity = 47/60 (78.33%), Postives = 54/60 (90.00%), Query Frame = 3

Query:  531 PLYVNAKQYNRILKRRQARAKLEAQGRLPKGRSKYLHESRHKHAMNRVRGEGGKFCSIKK 710
            PLYVNAKQY+RILKRRQARAKLEA+G++PK R KYLHESRH+HAM R RGEGG+F S K+
Sbjct:  264 PLYVNAKQYHRILKRRQARAKLEAEGKIPKERRKYLHESRHRHAMARKRGEGGRFFSPKE 323

[Close]

BLAST of nuclear factor Y complex A vs. UniProt/SwissProt
Match: sp|P23708|NFYA_MOUSE (Nuclear transcription factor Y subunit alpha OS=Mus musculus OX=10090 GN=Nfya PE=1 SV=2)

HSP 1 Score: 108.612 bits (270), Expect = 1.761e-25
Identity = 47/60 (78.33%), Postives = 54/60 (90.00%), Query Frame = 3

Query:  531 PLYVNAKQYNRILKRRQARAKLEAQGRLPKGRSKYLHESRHKHAMNRVRGEGGKFCSIKK 710
            PLYVNAKQY+RILKRRQARAKLEA+G++PK R KYLHESRH+HAM R RGEGG+F S K+
Sbjct:  263 PLYVNAKQYHRILKRRQARAKLEAEGKIPKERRKYLHESRHRHAMARKRGEGGRFFSPKE 322

[Close]

BLAST of nuclear factor Y complex A vs. UniProt/SwissProt
Match: sp|P23511|NFYA_HUMAN (Nuclear transcription factor Y subunit alpha OS=Homo sapiens OX=9606 GN=NFYA PE=1 SV=2)

HSP 1 Score: 108.612 bits (270), Expect = 1.880e-25
Identity = 47/60 (78.33%), Postives = 54/60 (90.00%), Query Frame = 3

Query:  531 PLYVNAKQYNRILKRRQARAKLEAQGRLPKGRSKYLHESRHKHAMNRVRGEGGKFCSIKK 710
            PLYVNAKQY+RILKRRQARAKLEA+G++PK R KYLHESRH+HAM R RGEGG+F S K+
Sbjct:  264 PLYVNAKQYHRILKRRQARAKLEAEGKIPKERRKYLHESRHRHAMARKRGEGGRFFSPKE 323

[Close]

BLAST of nuclear factor Y complex A vs. UniProt/SwissProt
Match: sp|P18576|NFYA_RAT (Nuclear transcription factor Y subunit alpha OS=Rattus norvegicus OX=10116 GN=Nfya PE=1 SV=1)

HSP 1 Score: 107.842 bits (268), Expect = 3.287e-25
Identity = 47/60 (78.33%), Postives = 54/60 (90.00%), Query Frame = 3

Query:  531 PLYVNAKQYNRILKRRQARAKLEAQGRLPKGRSKYLHESRHKHAMNRVRGEGGKFCSIKK 710
            PLYVNAKQY+RILKRRQARAKLEA+G++PK R KYLHESRH+HAM R RGEGG+F S K+
Sbjct:  258 PLYVNAKQYHRILKRRQARAKLEAEGKIPKERRKYLHESRHRHAMARKRGEGGRFFSPKE 317

[Close]

BLAST of nuclear factor Y complex A vs. UniProt/SwissProt
Match: sp|Q5E9S2|NFYA_BOVIN (Nuclear transcription factor Y subunit alpha OS=Bos taurus OX=9913 GN=NFYA PE=2 SV=1)

HSP 1 Score: 107.842 bits (268), Expect = 3.287e-25
Identity = 47/60 (78.33%), Postives = 54/60 (90.00%), Query Frame = 3

Query:  531 PLYVNAKQYNRILKRRQARAKLEAQGRLPKGRSKYLHESRHKHAMNRVRGEGGKFCSIKK 710
            PLYVNAKQY+RILKRRQARAKLEA+G++PK R KYLHESRH+HAM R RGEGG+F S K+
Sbjct:  258 PLYVNAKQYHRILKRRQARAKLEAEGKIPKERRKYLHESRHRHAMARKRGEGGRFFSPKE 317

[Close]

BLAST of nuclear factor Y complex A vs. UniProt/SwissProt
Match: sp|P06774|HAP2_YEAST (Transcriptional activator HAP2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=HAP2 PE=1 SV=1)

HSP 1 Score: 89.7373 bits (221), Expect = 2.462e-19
Identity = 40/57 (70.18%), Postives = 45/57 (78.95%), Query Frame = 3

Query:  531 PLYVNAKQYNRILKRRQARAKLEAQGRLPKGRSKYLHESRHKHAMNRVRGEGGKFCS 701
            P YVNAKQY RILKRR ARAKLE + R+ + R  YLHESRHKHAM R RGEGG+F +
Sbjct:  160 PFYVNAKQYYRILKRRYARAKLEEKLRISRERKPYLHESRHKHAMRRPRGEGGRFLT 216

[Close]

BLAST of nuclear factor Y complex A vs. TrEMBL
Match: A0A0F7GYF7 (Nuclear factor Y complex A (Fragment) OS=Schmidtea mediterranea OX=79327 PE=2 SV=1)

HSP 1 Score: 435.647 bits (1119), Expect = 3.654e-151
Identity = 253/253 (100.00%), Postives = 253/253 (100.00%), Query Frame = 3

Query:  174 NPMDKNNGNATLVQNHNAQVTLTQPIVLAQGQGGNTILGIQTSDGNIIPLQLASNPNGSQVMMVVPSQISTQSANLTGQVTSVASHDQVPQCVQPTQIIGSYXXXXXXXXXXXXXXXXXPLYVNAKQYNRILKRRQARAKLEAQGRLPKGRSKYLHESRHKHAMNRVRGEGGKFCSIKKTSKNEIHXXXXXXXXXXXXXXXXXXLRSSQSTTQIIQLPQLQKYVIASNFPSSQLVNTSNGLIYEVKVEPPTTV 932
            NPMDKNNGNATLVQNHNAQVTLTQPIVLAQGQGGNTILGIQTSDGNIIPLQLASNPNGSQVMMVVPSQISTQSANLTGQVTSVASHDQVPQCVQPTQIIGSYETEQISEENSQQNAQEEPLYVNAKQYNRILKRRQARAKLEAQGRLPKGRSKYLHESRHKHAMNRVRGEGGKFCSIKKTSKNEIHQSMNSQNTVTSTQNTNTNLRSSQSTTQIIQLPQLQKYVIASNFPSSQLVNTSNGLIYEVKVEPPTTV
Sbjct:    1 NPMDKNNGNATLVQNHNAQVTLTQPIVLAQGQGGNTILGIQTSDGNIIPLQLASNPNGSQVMMVVPSQISTQSANLTGQVTSVASHDQVPQCVQPTQIIGSYETEQISEENSQQNAQEEPLYVNAKQYNRILKRRQARAKLEAQGRLPKGRSKYLHESRHKHAMNRVRGEGGKFCSIKKTSKNEIHQSMNSQNTVTSTQNTNTNLRSSQSTTQIIQLPQLQKYVIASNFPSSQLVNTSNGLIYEVKVEPPTTV 253

[Close]

BLAST of nuclear factor Y complex A vs. TrEMBL
Match: A0A182BAE4 (Nuclear factor-Y subunit A1 OS=Schmidtea mediterranea OX=79327 GN=NF-YA1 PE=2 SV=1)

HSP 1 Score: 432.18 bits (1110), Expect = 7.952e-150
Identity = 251/251 (100.00%), Postives = 251/251 (100.00%), Query Frame = 3

Query:  180 MDKNNGNATLVQNHNAQVTLTQPIVLAQGQGGNTILGIQTSDGNIIPLQLASNPNGSQVMMVVPSQISTQSANLTGQVTSVASHDQVPQCVQPTQIIGSYXXXXXXXXXXXXXXXXXPLYVNAKQYNRILKRRQARAKLEAQGRLPKGRSKYLHESRHKHAMNRVRGEGGKFCSIKKTSKNEIHXXXXXXXXXXXXXXXXXXLRSSQSTTQIIQLPQLQKYVIASNFPSSQLVNTSNGLIYEVKVEPPTTV 932
            MDKNNGNATLVQNHNAQVTLTQPIVLAQGQGGNTILGIQTSDGNIIPLQLASNPNGSQVMMVVPSQISTQSANLTGQVTSVASHDQVPQCVQPTQIIGSYETEQISEENSQQNAQEEPLYVNAKQYNRILKRRQARAKLEAQGRLPKGRSKYLHESRHKHAMNRVRGEGGKFCSIKKTSKNEIHQSMNSQNTVTSTQNTNTNLRSSQSTTQIIQLPQLQKYVIASNFPSSQLVNTSNGLIYEVKVEPPTTV
Sbjct:    1 MDKNNGNATLVQNHNAQVTLTQPIVLAQGQGGNTILGIQTSDGNIIPLQLASNPNGSQVMMVVPSQISTQSANLTGQVTSVASHDQVPQCVQPTQIIGSYETEQISEENSQQNAQEEPLYVNAKQYNRILKRRQARAKLEAQGRLPKGRSKYLHESRHKHAMNRVRGEGGKFCSIKKTSKNEIHQSMNSQNTVTSTQNTNTNLRSSQSTTQIIQLPQLQKYVIASNFPSSQLVNTSNGLIYEVKVEPPTTV 251

[Close]

BLAST of nuclear factor Y complex A vs. TrEMBL
Match: A0A182BAE5 (Nuclear factor-Y subunit A2 OS=Schmidtea mediterranea OX=79327 GN=NF-YA2 PE=2 SV=1)

HSP 1 Score: 131.724 bits (330), Expect = 1.489e-32
Identity = 92/232 (39.66%), Postives = 124/232 (53.45%), Query Frame = 3

Query:  246 PIVLAQGQGGNTILGIQTSDGNIIPLQLASN--PNGSQVMMVVPSQISTQSANLTGQVTSVASHDQVPQCVQPTQIIGSYXXXXXXXXXXXXXXXXXPLYVNAKQYNRILKRRQARAKLEAQGRLPKGRSKYLHESRHKHAMNRVRGEGGKFCSIKKTSKNEIHXXXXXXXXXXXXXXXXXXLRSSQSTTQIIQLPQLQKYVIASNFPSSQLVN----TSNGLIYEVKVEPP 923
            P+VL     G + L IQT DG+IIP+Q  +N   N   ++M+  + I   +   +G   S AS D V                         N  EEPLYVNAKQYNRILKRR AR KLEAQGR+PK R KYLHESRHKHAMNR+RG GG+F S++   +N+   +  + N   +  +  + +  SQS              ++  F S +LV+    T+N +I E+K+EPP
Sbjct:   32 PLVLTTSSDGTSFLAIQTVDGHIIPIQFVTNGTSNSHNLVMMPATTIDNTNHTESG---SQASTDPVKD--------------------EAINNAEEPLYVNAKQYNRILKRRAARTKLEAQGRIPKERKKYLHESRHKHAMNRIRGSGGRFYSVQSEIQNQ-ENNQKNTNVTNNDISRKSYVNGSQSN-------------VSYGF-SRELVSLAAKTTNNVIIELKLEPP 225

[Close]

BLAST of nuclear factor Y complex A vs. TrEMBL
Match: A0A504XZE4 (Nuclear transcription factor Y subunit alpha OS=Fasciola gigantica OX=46835 GN=FGIG_00026 PE=4 SV=1)

HSP 1 Score: 130.954 bits (328), Expect = 4.654e-32
Identity = 86/215 (40.00%), Postives = 113/215 (52.56%), Query Frame = 3

Query:  237 LTQPIVL-AQGQGGNTILGIQTSDGNIIPLQLASNPNGSQVMMVVPSQ----------ISTQSANLTG-------QVTSVASHDQ-----------------------VPQCVQPTQII--------GSYXXXXXXXXXXXXXXX-----XXPLYVNAKQYNRILKRRQARAKLEAQGRLPKGRSKYLHESRHKHAMNRVRGEGGKFCSIKKTSK 719
            + QP+++ A G    T   +Q SDG++IP+QLA++  G QV+M +PS           I + + NL G       Q+ S A  D                        +PQ V  TQ++        G+      + + +   +      EEPLYVNAKQY+RILKRRQARAKLE+QGR+PK R KYLHESRHKHAMNRVR  GG+F SI   S 
Sbjct:   20 MQQPLLMDANGAAQPTTFAVQASDGSLIPVQLATSAGGGQVIMFLPSAAQQTIYATQPIVSAATNLDGSLTNTQGQIISTAVDDDNHILQQLQQTPHVQVLHQTQTTSIPQTVSSTQVVQVSSPKVEGALGDSVGAAQTAASVSPGLPVGEEPLYVNAKQYHRILKRRQARAKLESQGRIPKERPKYLHESRHKHAMNRVRSSGGRFFSIPNYSD 234

[Close]

BLAST of nuclear factor Y complex A vs. TrEMBL
Match: A0A2H1CRY0 (CCAAT-binding transcription factor subunit B OS=Fasciola hepatica OX=6192 GN=D915_02266 PE=4 SV=1)

HSP 1 Score: 130.954 bits (328), Expect = 9.134e-32
Identity = 86/215 (40.00%), Postives = 113/215 (52.56%), Query Frame = 3

Query:  237 LTQPIVL-AQGQGGNTILGIQTSDGNIIPLQLASNPNGSQVMMVVPSQ----------ISTQSANLTG-------QVTSVASHDQ-----------------------VPQCVQPTQII--------GSYXXXXXXXXXXXXXX-----XXXPLYVNAKQYNRILKRRQARAKLEAQGRLPKGRSKYLHESRHKHAMNRVRGEGGKFCSIKKTSK 719
            + QP+++ A G    T   +Q SDG++IP+QLA++  G QV+M +PS           I + + NL G       Q+ S A  D                        +PQ V  TQ++        G+      + + +   +      EEPLYVNAKQY+RILKRRQARAKLE+QGR+PK R KYLHESRHKHAMNRVR  GG+F SI   S 
Sbjct:   43 MQQPLLMDANGAAQPTTFAVQASDGSLIPVQLATSAGGGQVIMFLPSAAQQTIYATQPIVSAATNLDGSLTNTQGQIISTAVDDDNHILQQLQQAPHVQVLHQTQTTSIPQTVSSTQVVQVSSPKVEGALGDSVGAAQTAASVSPGLPVGEEPLYVNAKQYHRILKRRQARAKLESQGRIPKERPKYLHESRHKHAMNRVRSSGGRFFSIPNYSD 257

[Close]

BLAST of nuclear factor Y complex A vs. Ensembl Cavefish
Match: nfyal (nuclear transcription factor Y, alpha, like [Source:ZFIN;Acc:ZDB-GENE-040718-491])

HSP 1 Score: 106.686 bits (265), Expect = 2.945e-26
Identity = 46/63 (73.02%), Postives = 55/63 (87.30%), Query Frame = 3

Query:  531 PLYVNAKQYNRILKRRQARAKLEAQGRLPKGRSKYLHESRHKHAMNRVRGEGGKFCSIKKTSK 719
            PLYVNAKQY+RILKRRQARAKLEA+G++PK R KYLHESRH+HAM R RG+GG+F S K+  +
Sbjct:  199 PLYVNAKQYHRILKRRQARAKLEAEGKIPKERRKYLHESRHRHAMQRKRGDGGRFFSPKEKEE 261

[Close]

BLAST of nuclear factor Y complex A vs. Ensembl Sea Lamprey
Match: nfya (nuclear transcription factor Y, alpha [Source:ZFIN;Acc:ZDB-GENE-010501-1])

HSP 1 Score: 107.842 bits (268), Expect = 5.571e-27
Identity = 46/58 (79.31%), Postives = 53/58 (91.38%), Query Frame = 3

Query:  531 PLYVNAKQYNRILKRRQARAKLEAQGRLPKGRSKYLHESRHKHAMNRVRGEGGKFCSI 704
            PLYVNAKQY+RILKRRQARAKLEA+GR+PK R KYLHESRH+HAM R RGEGG+F ++
Sbjct:  265 PLYVNAKQYHRILKRRQARAKLEAEGRIPKERKKYLHESRHRHAMQRQRGEGGRFHTL 322

[Close]

BLAST of nuclear factor Y complex A vs. Ensembl Yeast
Match: HAP2 (Subunit of the Hap2p/3p/4p/5p CCAAT-binding complex; complex is heme-activated and glucose-repressed; complex is a transcriptional activator and global regulator of respiratory gene expression; contains sequences sufficient for both complex assembly and DNA binding; respiratory defect of the null mutant is functionally complemented by human NFYA [Source:SGD;Acc:S000003206])

HSP 1 Score: 89.7373 bits (221), Expect = 3.546e-21
Identity = 40/57 (70.18%), Postives = 45/57 (78.95%), Query Frame = 3

Query:  531 PLYVNAKQYNRILKRRQARAKLEAQGRLPKGRSKYLHESRHKHAMNRVRGEGGKFCS 701
            P YVNAKQY RILKRR ARAKLE + R+ + R  YLHESRHKHAM R RGEGG+F +
Sbjct:  160 PFYVNAKQYYRILKRRYARAKLEEKLRISRERKPYLHESRHKHAMRRPRGEGGRFLT 216

[Close]

BLAST of nuclear factor Y complex A vs. Ensembl Nematostella
Match: EDO48713 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RII3])

HSP 1 Score: 91.6633 bits (226), Expect = 2.916e-23
Identity = 41/57 (71.93%), Postives = 49/57 (85.96%), Query Frame = 3

Query:  531 PLYVNAKQYNRILKRRQARAKLEAQGRLPKGRSKYLHESRHKHAMNRVRGEGGKFCS 701
            PLYVNAKQY+RI+KRRQARAKLEA+G++PK R KYLHESRH+HA  R R  GG+F +
Sbjct:    7 PLYVNAKQYHRIIKRRQARAKLEAEGKIPKVRKKYLHESRHQHACRRKRSNGGRFVT 63

[Close]

BLAST of nuclear factor Y complex A vs. Ensembl Nematostella
Match: EDO27514 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T919])

HSP 1 Score: 92.4337 bits (228), Expect = 3.144e-23
Identity = 41/57 (71.93%), Postives = 49/57 (85.96%), Query Frame = 3

Query:  531 PLYVNAKQYNRILKRRQARAKLEAQGRLPKGRSKYLHESRHKHAMNRVRGEGGKFCS 701
            PLYVNAKQY+RI+KRRQARAKLEA+G++PK R KYLHESRH+HA  R R  GG+F +
Sbjct:    7 PLYVNAKQYHRIIKRRQARAKLEAEGKIPKVRKKYLHESRHQHACRRKRSNGGRFVT 63

[Close]

BLAST of nuclear factor Y complex A vs. Ensembl Medaka
Match: nfyal (nuclear transcription factor Y subunit alpha [Source:NCBI gene;Acc:101159350])

HSP 1 Score: 106.686 bits (265), Expect = 5.444e-26
Identity = 46/60 (76.67%), Postives = 53/60 (88.33%), Query Frame = 3

Query:  531 PLYVNAKQYNRILKRRQARAKLEAQGRLPKGRSKYLHESRHKHAMNRVRGEGGKFCSIKK 710
            PLYVNAKQY+RILKRRQARAKLEA+G++PK R KYLHESRH+HAM R RG+GG+F S K 
Sbjct:  230 PLYVNAKQYHRILKRRQARAKLEAEGKIPKERRKYLHESRHRHAMQRKRGDGGRFFSPKD 289

[Close]

BLAST of nuclear factor Y complex A vs. Planmine SMEST
Match: SMESG000045451.1 (SMESG000045451.1)

HSP 1 Score: 315.079 bits (806), Expect = 3.516e-108
Identity = 192/192 (100.00%), Postives = 192/192 (100.00%), Query Frame = 3

Query:  357 MMVVPSQISTQSANLTGQVTSVASHDQVPQCVQPTQIIGSYXXXXXXXXXXXXXXXXXPLYVNAKQYNRILKRRQARAKLEAQGRLPKGRSKYLHESRHKHAMNRVRGEGGKFCSIKKTSKNEIHXXXXXXXXXXXXXXXXXXLRSSQSTTQIIQLPQLQKYVIASNFPSSQLVNTSNGLIYEVKVEPPTTV 932
            MMVVPSQISTQSANLTGQVTSVASHDQVPQCVQPTQIIGSYETEQISEENSQQNAQEEPLYVNAKQYNRILKRRQARAKLEAQGRLPKGRSKYLHESRHKHAMNRVRGEGGKFCSIKKTSKNEIHQSMNSQNTVTSTQNTNTNLRSSQSTTQIIQLPQLQKYVIASNFPSSQLVNTSNGLIYEVKVEPPTTV
Sbjct:    1 MMVVPSQISTQSANLTGQVTSVASHDQVPQCVQPTQIIGSYETEQISEENSQQNAQEEPLYVNAKQYNRILKRRQARAKLEAQGRLPKGRSKYLHESRHKHAMNRVRGEGGKFCSIKKTSKNEIHQSMNSQNTVTSTQNTNTNLRSSQSTTQIIQLPQLQKYVIASNFPSSQLVNTSNGLIYEVKVEPPTTV 192

[Close]

BLAST of nuclear factor Y complex A vs. Planmine SMEST
Match: SMESG000045451.1 (SMESG000045451.1)

HSP 1 Score: 312.383 bits (799), Expect = 4.715e-107
Identity = 191/191 (100.00%), Postives = 191/191 (100.00%), Query Frame = 3

Query:  360 MVVPSQISTQSANLTGQVTSVASHDQVPQCVQPTQIIGSYXXXXXXXXXXXXXXXXXPLYVNAKQYNRILKRRQARAKLEAQGRLPKGRSKYLHESRHKHAMNRVRGEGGKFCSIKKTSKNEIHXXXXXXXXXXXXXXXXXXLRSSQSTTQIIQLPQLQKYVIASNFPSSQLVNTSNGLIYEVKVEPPTTV 932
            MVVPSQISTQSANLTGQVTSVASHDQVPQCVQPTQIIGSYETEQISEENSQQNAQEEPLYVNAKQYNRILKRRQARAKLEAQGRLPKGRSKYLHESRHKHAMNRVRGEGGKFCSIKKTSKNEIHQSMNSQNTVTSTQNTNTNLRSSQSTTQIIQLPQLQKYVIASNFPSSQLVNTSNGLIYEVKVEPPTTV
Sbjct:    1 MVVPSQISTQSANLTGQVTSVASHDQVPQCVQPTQIIGSYETEQISEENSQQNAQEEPLYVNAKQYNRILKRRQARAKLEAQGRLPKGRSKYLHESRHKHAMNRVRGEGGKFCSIKKTSKNEIHQSMNSQNTVTSTQNTNTNLRSSQSTTQIIQLPQLQKYVIASNFPSSQLVNTSNGLIYEVKVEPPTTV 191

[Close]

BLAST of nuclear factor Y complex A vs. Planmine SMEST
Match: SMESG000010136.1 (SMESG000010136.1)

HSP 1 Score: 112.464 bits (280), Expect = 1.213e-29
Identity = 65/135 (48.15%), Postives = 86/135 (63.70%), Query Frame = 3

Query:  531 PLYVNAKQYNRILKRRQARAKLEAQGRLPKGRSKYLHESRHKHAMNRVRGEGGKFCSIKKTSKNEIHXXXXXXXXXXXXXXXXXXLRSSQSTTQIIQLPQLQKYVIASNFPSSQLVN----TSNGLIYEVKVEPP 923
            PLYVNAKQYNRILKRR AR KLEAQGR+PK R KYLHESRHKHAMNR+RG GG+F S++   +N+   +  + N   +  +  + +  SQS              ++  F S +LV+    T+N +I E+K+EPP
Sbjct:   34 PLYVNAKQYNRILKRRAARTKLEAQGRIPKERKKYLHESRHKHAMNRIRGSGGRFYSVQSEIQNQ-ENNQKNTNVTNNDISRKSYVNGSQSN-------------VSYGF-SRELVSLAAKTTNNVIIELKLEPP 153

[Close]

BLAST of nuclear factor Y complex A vs. Planmine SMEST
Match: SMESG000010136.1 (SMESG000010136.1)

HSP 1 Score: 112.079 bits (279), Expect = 1.328e-29
Identity = 65/135 (48.15%), Postives = 86/135 (63.70%), Query Frame = 3

Query:  531 PLYVNAKQYNRILKRRQARAKLEAQGRLPKGRSKYLHESRHKHAMNRVRGEGGKFCSIKKTSKNEIHXXXXXXXXXXXXXXXXXXLRSSQSTTQIIQLPQLQKYVIASNFPSSQLVN----TSNGLIYEVKVEPP 923
            PLYVNAKQYNRILKRR AR KLEAQGR+PK R KYLHESRHKHAMNR+RG GG+F S++   +N+   +  + N   +  +  + +  SQS              ++  F S +LV+    T+N +I E+K+EPP
Sbjct:   35 PLYVNAKQYNRILKRRAARTKLEAQGRIPKERKKYLHESRHKHAMNRIRGSGGRFYSVQSEIQNQ-ENNQKNTNVTNNDISRKSYVNGSQSN-------------VSYGF-SRELVSLAAKTTNNVIIELKLEPP 154

[Close]

BLAST of nuclear factor Y complex A vs. Planmine SMEST
Match: SMESG000031441.1 (SMESG000031441.1)

HSP 1 Score: 69.707 bits (169), Expect = 4.209e-14
Identity = 39/67 (58.21%), Postives = 47/67 (70.15%), Query Frame = 3

Query:  534 LYVNAKQYNRILKRRQARAKLEAQGRLPKG-RSKYLHESRHKHAMNRVRGEGGKFCSIKKTSKNEIH 731
            L+VN KQYNRILKRR ARAKL    +L  G RS+Y++ESR KHA+NR R  GG+F   KK S N + 
Sbjct:   87 LFVNPKQYNRILKRRVARAKL----KLRTGERSRYMYESRRKHALNRARSIGGQFT--KKNSANTLE 147

The following BLAST results are available for this feature:

BLAST of nuclear factor Y complex A vs. Ensembl Human
BLAST of nuclear factor Y complex A vs. Ensembl Celegans
BLAST of nuclear factor Y complex A vs. Ensembl Fly
BLAST of nuclear factor Y complex A vs. Ensembl Zebrafish
BLAST of nuclear factor Y complex A vs. Ensembl Xenopus
BLAST of nuclear factor Y complex A vs. Ensembl Mouse
BLAST of nuclear factor Y complex A vs. UniProt/SwissProt
BLAST of nuclear factor Y complex A vs. TrEMBL
BLAST of nuclear factor Y complex A vs. Ensembl Cavefish
BLAST of nuclear factor Y complex A vs. Ensembl Sea Lamprey
BLAST of nuclear factor Y complex A vs. Ensembl Yeast
BLAST of nuclear factor Y complex A vs. Ensembl Nematostella
BLAST of nuclear factor Y complex A vs. Ensembl Medaka
BLAST of nuclear factor Y complex A vs. Planmine SMEST

BLAST of nuclear factor Y complex A vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 2


Match Name	E-value	Identity	Description
NFYA	3.724e-26	78.33	nuclear transcription factor Y subunit alpha [Sour...	[more]
NFYA	3.915e-26	78.33	nuclear transcription factor Y subunit alpha [Sour...	[more]

BLAST of nuclear factor Y complex A vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 4


Match Name	E-value	Identity	Description
nfya-1	8.557e-17	59.32	Nuclear transcription Factor Y, A (Alpha) subunit ...	[more]
nfya-2	4.552e-13	56.36	Nuclear transcription Factor Y, A (Alpha) subunit ...	[more]
nfya-2	6.103e-13	56.36	Nuclear transcription Factor Y, A (Alpha) subunit ...	[more]
nfya-2	1.319e-12	57.69	Nuclear transcription Factor Y, A (Alpha) subunit ...	[more]

BLAST of nuclear factor Y complex A vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 1


Match Name	E-value	Identity	Description
Nf-YA	2.189e-22	75.00	gene:FBgn0035993 transcript:FBtr0076504	[more]

BLAST of nuclear factor Y complex A vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
nfyal	2.918e-26	74.60	nuclear transcription factor Y, alpha, like [Sourc...	[more]
nfyal	4.360e-26	74.60	nuclear transcription factor Y, alpha, like [Sourc...	[more]
nfya	4.621e-26	73.02	nuclear transcription factor Y, alpha [Source:ZFIN...	[more]
nfya	1.117e-25	73.02	nuclear transcription factor Y, alpha [Source:ZFIN...	[more]
nfya	1.223e-25	73.02	nuclear transcription factor Y, alpha [Source:ZFIN...	[more]

BLAST of nuclear factor Y complex A vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 2


Match Name	E-value	Identity	Description
nfya	1.180e-25	69.70	nuclear transcription factor Y subunit alpha [Sour...	[more]
nfya	1.253e-25	69.70	nuclear transcription factor Y subunit alpha [Sour...	[more]

BLAST of nuclear factor Y complex A vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Nfya	7.345e-27	78.33	nuclear transcription factor-Y alpha [Source:MGI S...	[more]
Nfya	7.345e-27	78.33	nuclear transcription factor-Y alpha [Source:MGI S...	[more]
Nfya	2.517e-26	78.33	nuclear transcription factor-Y alpha [Source:MGI S...	[more]
Nfya	2.517e-26	78.33	nuclear transcription factor-Y alpha [Source:MGI S...	[more]
Nfya	2.557e-26	78.33	nuclear transcription factor-Y alpha [Source:MGI S...	[more]

BLAST of nuclear factor Y complex A vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|P23708\|NFYA_MOUSE	1.761e-25	78.33	Nuclear transcription factor Y subunit alpha OS=Mu...	[more]
sp\|P23511\|NFYA_HUMAN	1.880e-25	78.33	Nuclear transcription factor Y subunit alpha OS=Ho...	[more]
sp\|P18576\|NFYA_RAT	3.287e-25	78.33	Nuclear transcription factor Y subunit alpha OS=Ra...	[more]
sp\|Q5E9S2\|NFYA_BOVIN	3.287e-25	78.33	Nuclear transcription factor Y subunit alpha OS=Bo...	[more]
sp\|P06774\|HAP2_YEAST	2.462e-19	70.18	Transcriptional activator HAP2 OS=Saccharomyces ce...	[more]

BLAST of nuclear factor Y complex A vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A0F7GYF7	3.654e-151	100.00	Nuclear factor Y complex A (Fragment) OS=Schmidtea...	[more]
A0A182BAE4	7.952e-150	100.00	Nuclear factor-Y subunit A1 OS=Schmidtea mediterra...	[more]
A0A182BAE5	1.489e-32	39.66	Nuclear factor-Y subunit A2 OS=Schmidtea mediterra...	[more]
A0A504XZE4	4.654e-32	40.00	Nuclear transcription factor Y subunit alpha OS=Fa...	[more]
A0A2H1CRY0	9.134e-32	40.00	CCAAT-binding transcription factor subunit B OS=Fa...	[more]

BLAST of nuclear factor Y complex A vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 1


Match Name	E-value	Identity	Description
nfyal	2.945e-26	73.02	nuclear transcription factor Y, alpha, like [Sourc...	[more]

BLAST of nuclear factor Y complex A vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1


Match Name	E-value	Identity	Description
nfya	5.571e-27	79.31	nuclear transcription factor Y, alpha [Source:ZFIN...	[more]

BLAST of nuclear factor Y complex A vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1


Match Name	E-value	Identity	Description
HAP2	3.546e-21	70.18	Subunit of the Hap2p/3p/4p/5p CCAAT-binding comple...	[more]

BLAST of nuclear factor Y complex A vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 2


Match Name	E-value	Identity	Description
EDO48713	2.916e-23	71.93	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO27514	3.144e-23	71.93	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of nuclear factor Y complex A vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 1


Match Name	E-value	Identity	Description
nfyal	5.444e-26	76.67	nuclear transcription factor Y subunit alpha [Sour...	[more]

BLAST of nuclear factor Y complex A vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000045451.1	3.516e-108	100.00	SMESG000045451.1	[more]
SMESG000045451.1	4.715e-107	100.00	SMESG000045451.1	[more]
SMESG000010136.1	1.213e-29	48.15	SMESG000010136.1	[more]
SMESG000010136.1	1.328e-29	48.15	SMESG000010136.1	[more]
SMESG000031441.1	4.209e-14	58.21	SMESG000031441.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Cross References

External references for this transcript


Database	Accession
SmedGD GBrowse	SMED30017865
GenBank	AKG62116.1

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30017865 ID=SMED30017865|Name=nuclear factor Y complex A|organism=Schmidtea mediterranea sexual|type=transcript|length=1091bp
ATCTATATAAATCTTATATGTATCATTTCTCAAATTTTAAATGACCTTGG
TTTAATTATATCAGTTGATGTATAGCACCAATGGAGTAAATTCATTTATA
TTTATGATTAGTTTGATTCGTTGTCGAACGGGATCATAGATAGAACATCC
AATCAGTGATATATCAATATTGAAATCCAATGGATAAGAATAATGGTAAT
GCAACTTTGGTACAGAATCATAATGCACAAGTCACACTTACTCAGCCTAT
TGTCCTGGCTCAAGGTCAAGGTGGAAATACTATTTTAGGAATCCAAACTA
GTGATGGAAATATAATCCCTTTGCAATTAGCATCGAATCCCAATGGTAGT
CAAGTAATGATGGTCGTACCTTCTCAGATATCTACTCAATCTGCAAACTT
GACAGGTCAAGTAACTAGTGTCGCAAGTCATGATCAAGTTCCACAGTGCG
TGCAACCAACTCAGATTATTGGTAGTTATGAAACGGAACAGATATCAGAA
GAAAATTCTCAGCAAAATGCCCAAGAAGAACCACTTTATGTAAACGCAAA
GCAATATAATCGAATACTCAAACGTAGGCAAGCCAGAGCAAAGCTTGAAG
CTCAAGGTCGATTGCCGAAAGGTAGGAGTAAATATTTACATGAATCAAGA
CATAAGCATGCCATGAATCGAGTAAGAGGTGAAGGTGGGAAGTTCTGCTC
TATTAAGAAAACATCAAAAAATGAAATTCACCAGTCAATGAATAGTCAGA
ATACTGTAACATCTACACAAAACACAAATACGAATTTAAGATCATCTCAA
AGCACAACTCAGATTATACAATTACCACAATTACAAAAATATGTTATCGC
GTCCAATTTCCCATCCAGCCAACTGGTTAATACTAGCAATGGTCTGATTT
ACGAAGTGAAAGTTGAACCTCCTACTACTGTCTAATGTTATAATTGTAAA
CATGATTTATCTCTCTCTCTCTCTCTGTTTTGAATGTGTTCATCGATGTT
ATTTGAATGAAAATATTCATTGATAAGTGAATGAATTTTAATAATGAACA
ATCGCATATTTTATTGTGTATAAATATTTTATGTAAATAAG

protein sequence of SMED30017865-orf-1

>SMED30017865-orf-1 ID=SMED30017865-orf-1|Name=SMED30017865-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=252bp
MDKNNGNATLVQNHNAQVTLTQPIVLAQGQGGNTILGIQTSDGNIIPLQL
ASNPNGSQVMMVVPSQISTQSANLTGQVTSVASHDQVPQCVQPTQIIGSY
ETEQISEENSQQNAQEEPLYVNAKQYNRILKRRQARAKLEAQGRLPKGRS
KYLHESRHKHAMNRVRGEGGKFCSIKKTSKNEIHQSMNSQNTVTSTQNTN
TNLRSSQSTTQIIQLPQLQKYVIASNFPSSQLVNTSNGLIYEVKVEPPTT
V*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000208	testis
PLANA:0002111	X2 cell

Vocabulary: **INTERPRO**
Term	Definition
IPR001289	NFYA
IPR018362	CCAAT-binding_factor_CS

Vocabulary: **molecular function**
Term	Definition
GO:0003700	transcription factor activity, sequence-specific DNA binding
GO:0003677	DNA binding

Vocabulary: **biological process**
Term	Definition
GO:0006355	regulation of transcription, DNA-templated

Vocabulary: **cellular component**
Term	Definition
GO:0016602	CCAAT-binding factor complex

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR001289	Nuclear transcription factor Y subunit A	PRINTS	PR00616	CCAATSUBUNTB	coord: 118..140 score: 83.33 coord: 149..172 score: 72.92
IPR001289	Nuclear transcription factor Y subunit A	SMART	SM00521	cbf3	coord: 114..175 e-value: 3.5E-34 score: 129.5
IPR001289	Nuclear transcription factor Y subunit A	PFAM	PF02045	CBFB_NFYA	coord: 117..172 e-value: 8.4E-28 score: 96.8
IPR001289	Nuclear transcription factor Y subunit A	PANTHER	PTHR12632	TRANSCRIPTION FACTOR NF-Y ALPHA-RELATED	coord: 61..208
IPR001289	Nuclear transcription factor Y subunit A	PROSITE	PS51152	NFYA_HAP2_2	coord: 115..175 score: 35.722
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 185..206
None	No IPR available	PANTHER	PTHR12632:SF6	NUCLEAR TRANSCRIPTION FACTOR Y SUBUNIT ALPHA	coord: 61..208
IPR018362	CCAAT-binding factor, conserved site	PROSITE	PS00686	NFYA_HAP2_1	coord: 120..140