Jagged 2-1
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30017862 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 6
Homology
BLAST of Jagged 2-1 vs. Ensembl Human
Match: NOTCH4 (notch receptor 4 [Source:HGNC Symbol;Acc:HGNC:7884]) HSP 1 Score: 66.2402 bits (160), Expect = 1.745e-10 Identity = 32/96 (33.33%), Postives = 45/96 (46.88%), Query Frame = 3
Query: 720 CYNNGFCVNKGSTFECKCMESYSGKFCE-FANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKC--DLKVVQTCKCPENMRCNYSESGVLFSC 998
C+N G CV+ G ++ C C + G C+ NPC PCQN C +P+G Y C C G+ G C +L Q+ C + C G +C
Sbjct: 900 CHNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSG--YLCQCAPGYDGQNCSKELDACQSQPCHNHGTCTPKPGGFHCAC 993 HSP 2 Score: 57.3806 bits (137), Expect = 8.220e-8 Identity = 35/110 (31.82%), Postives = 47/110 (42.73%), Query Frame = 3
Query: 681 KCLPNNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFCE--FANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCD--LKVVQTCKCPENMRCNYSESGVLFSC 998
+C + S C+N G CVN+ TF C C + G CE C +PC+N C P G C C TG+ G C + + CP N C ++G F C
Sbjct: 762 QCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGPR--CLCPTGYTGGSCQTLMDLCAQKPCPRNSHC--LQTGPSFHC 867 HSP 3 Score: 53.9138 bits (128), Expect = 1.161e-6 Identity = 32/126 (25.40%), Postives = 51/126 (40.48%), Query Frame = 3
Query: 549 ECENGYYPAKQCNKFCFPSENEYTC---DGFGNKICKEGLYFDADENKCLPNNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFCEFANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKC 917
ECE P + C S + C G+G C+E L ++CIA++ C C+++ +F C C +G C + C PC +C P + C C+ G++G C
Sbjct: 316 ECETQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENL-----------DDCIAAT--CAPGSTCIDRVGSFSCLCPPGRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTC 428 HSP 4 Score: 53.5286 bits (127), Expect = 1.486e-6 Identity = 40/141 (28.37%), Postives = 56/141 (39.72%), Query Frame = 3
Query: 546 HECENGYYPAKQCNKFCFPSENEYTCDGFGNKICKEGLYFDADENKCLPNNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFCEF-ANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCDLKVVQTCKCPENMRC 965
H+ NG+ QC C P GF C+E D DE + P C N G C ++ F CKC+ + G C+ + C +PC C P A+FC C +GF G C++ + C C
Sbjct: 528 HDLLNGF----QC--ICLP--------GFSGTRCEE----DIDECRSSP---------CANGGQCQDQPGAFHCKCLPGFEGPRCQTEVDECLSDPCPVGASCLDLP--GAFFCLCPSGFTGQLCEVPLCAPNLCQPKQIC 639 HSP 5 Score: 52.373 bits (124), Expect = 3.011e-6 Identity = 33/108 (30.56%), Postives = 51/108 (47.22%), Query Frame = 3
Query: 651 EGLYFDADENKCLPNNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFCEF-ANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCDLKVVQTCK--CPENMRC 965
EG + + N+C +S C N+ C + + F+C C+ +SG CE + C +PC N G+C +P A+ C C GF G +C +V + CP C
Sbjct: 505 EGQLCEVETNEC-------ASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQDQP--GAFHCKCLPGFEGPRCQTEVDECLSDPCPVGASC 603
BLAST of Jagged 2-1 vs. Ensembl Human
Match: NOTCH4 (notch receptor 4 [Source:HGNC Symbol;Acc:HGNC:7884]) HSP 1 Score: 66.2402 bits (160), Expect = 1.745e-10 Identity = 32/96 (33.33%), Postives = 45/96 (46.88%), Query Frame = 3
Query: 720 CYNNGFCVNKGSTFECKCMESYSGKFCE-FANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKC--DLKVVQTCKCPENMRCNYSESGVLFSC 998
C+N G CV+ G ++ C C + G C+ NPC PCQN C +P+G Y C C G+ G C +L Q+ C + C G +C
Sbjct: 901 CHNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSG--YLCQCAPGYDGQNCSKELDACQSQPCHNHGTCTPKPGGFHCAC 994 HSP 2 Score: 54.299 bits (129), Expect = 8.692e-7 Identity = 34/110 (30.91%), Postives = 46/110 (41.82%), Query Frame = 3
Query: 681 KCLPNNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFCE--FANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCD--LKVVQTCKCPENMRCNYSESGVLFSC 998
+C + S C+N G CVN+ TF C C + G CE C +PC+N C P G C C T + G C + + CP N C ++G F C
Sbjct: 763 QCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGPR--CLCPTVYTGGSCQTLMDLCAQKPCPRNSHC--LQTGPSFHC 868 HSP 3 Score: 53.9138 bits (128), Expect = 1.161e-6 Identity = 32/126 (25.40%), Postives = 51/126 (40.48%), Query Frame = 3
Query: 549 ECENGYYPAKQCNKFCFPSENEYTC---DGFGNKICKEGLYFDADENKCLPNNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFCEFANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKC 917
ECE P + C S + C G+G C+E L ++CIA++ C C+++ +F C C +G C + C PC +C P + C C+ G++G C
Sbjct: 317 ECETQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENL-----------DDCIAAT--CAPGSTCIDRVGSFSCLCPPGRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTC 429 HSP 4 Score: 53.5286 bits (127), Expect = 1.486e-6 Identity = 40/141 (28.37%), Postives = 56/141 (39.72%), Query Frame = 3
Query: 546 HECENGYYPAKQCNKFCFPSENEYTCDGFGNKICKEGLYFDADENKCLPNNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFCEF-ANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCDLKVVQTCKCPENMRC 965
H+ NG+ QC C P GF C+E D DE + P C N G C ++ F CKC+ + G C+ + C +PC C P A+FC C +GF G C++ + C C
Sbjct: 529 HDLLNGF----QC--ICLP--------GFSGTRCEE----DIDECRSSP---------CANGGQCQDQPGAFHCKCLPGFEGPRCQTEVDECLSDPCPVGASCLDLP--GAFFCLCPSGFTGQLCEVPLCAPNLCQPKQIC 640 HSP 5 Score: 52.373 bits (124), Expect = 3.011e-6 Identity = 33/108 (30.56%), Postives = 51/108 (47.22%), Query Frame = 3
Query: 651 EGLYFDADENKCLPNNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFCEF-ANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCDLKVVQTCK--CPENMRC 965
EG + + N+C +S C N+ C + + F+C C+ +SG CE + C +PC N G+C +P A+ C C GF G +C +V + CP C
Sbjct: 506 EGQLCEVETNEC-------ASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQDQP--GAFHCKCLPGFEGPRCQTEVDECLSDPCPVGASC 604
BLAST of Jagged 2-1 vs. Ensembl Human
Match: NOTCH4 (notch receptor 4 [Source:HGNC Symbol;Acc:HGNC:7884]) HSP 1 Score: 66.2402 bits (160), Expect = 1.745e-10 Identity = 32/96 (33.33%), Postives = 45/96 (46.88%), Query Frame = 3
Query: 720 CYNNGFCVNKGSTFECKCMESYSGKFCE-FANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKC--DLKVVQTCKCPENMRCNYSESGVLFSC 998
C+N G CV+ G ++ C C + G C+ NPC PCQN C +P+G Y C C G+ G C +L Q+ C + C G +C
Sbjct: 901 CHNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSG--YLCQCAPGYDGQNCSKELDACQSQPCHNHGTCTPKPGGFHCAC 994 HSP 2 Score: 57.3806 bits (137), Expect = 8.220e-8 Identity = 35/110 (31.82%), Postives = 47/110 (42.73%), Query Frame = 3
Query: 681 KCLPNNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFCE--FANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCD--LKVVQTCKCPENMRCNYSESGVLFSC 998
+C + S C+N G CVN+ TF C C + G CE C +PC+N C P G C C TG+ G C + + CP N C ++G F C
Sbjct: 763 QCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGPR--CLCPTGYTGGSCQTLMDLCAQKPCPRNSHC--LQTGPSFHC 868 HSP 3 Score: 53.9138 bits (128), Expect = 1.161e-6 Identity = 32/126 (25.40%), Postives = 51/126 (40.48%), Query Frame = 3
Query: 549 ECENGYYPAKQCNKFCFPSENEYTC---DGFGNKICKEGLYFDADENKCLPNNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFCEFANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKC 917
ECE P + C S + C G+G C+E L ++CIA++ C C+++ +F C C +G C + C PC +C P + C C+ G++G C
Sbjct: 317 ECETQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENL-----------DDCIAAT--CAPGSTCIDRVGSFSCLCPPGRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTC 429 HSP 4 Score: 53.5286 bits (127), Expect = 1.486e-6 Identity = 40/141 (28.37%), Postives = 56/141 (39.72%), Query Frame = 3
Query: 546 HECENGYYPAKQCNKFCFPSENEYTCDGFGNKICKEGLYFDADENKCLPNNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFCEF-ANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCDLKVVQTCKCPENMRC 965
H+ NG+ QC C P GF C+E D DE + P C N G C ++ F CKC+ + G C+ + C +PC C P A+FC C +GF G C++ + C C
Sbjct: 529 HDLLNGF----QC--ICLP--------GFSGTRCEE----DIDECRSSP---------CANGGQCQDQPGAFHCKCLPGFEGPRCQTEVDECLSDPCPVGASCLDLP--GAFFCLCPSGFTGQLCEVPLCAPNLCQPKQIC 640 HSP 5 Score: 52.373 bits (124), Expect = 3.011e-6 Identity = 33/108 (30.56%), Postives = 51/108 (47.22%), Query Frame = 3
Query: 651 EGLYFDADENKCLPNNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFCEF-ANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCDLKVVQTCK--CPENMRC 965
EG + + N+C +S C N+ C + + F+C C+ +SG CE + C +PC N G+C +P A+ C C GF G +C +V + CP C
Sbjct: 506 EGQLCEVETNEC-------ASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQDQP--GAFHCKCLPGFEGPRCQTEVDECLSDPCPVGASC 604
BLAST of Jagged 2-1 vs. Ensembl Human
Match: NOTCH4 (notch receptor 4 [Source:HGNC Symbol;Acc:HGNC:7884]) HSP 1 Score: 66.2402 bits (160), Expect = 1.745e-10 Identity = 32/96 (33.33%), Postives = 45/96 (46.88%), Query Frame = 3
Query: 720 CYNNGFCVNKGSTFECKCMESYSGKFCE-FANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKC--DLKVVQTCKCPENMRCNYSESGVLFSC 998
C+N G CV+ G ++ C C + G C+ NPC PCQN C +P+G Y C C G+ G C +L Q+ C + C G +C
Sbjct: 901 CHNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSG--YLCQCAPGYDGQNCSKELDACQSQPCHNHGTCTPKPGGFHCAC 994 HSP 2 Score: 57.3806 bits (137), Expect = 8.220e-8 Identity = 35/110 (31.82%), Postives = 47/110 (42.73%), Query Frame = 3
Query: 681 KCLPNNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFCE--FANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCD--LKVVQTCKCPENMRCNYSESGVLFSC 998
+C + S C+N G CVN+ TF C C + G CE C +PC+N C P G C C TG+ G C + + CP N C ++G F C
Sbjct: 763 QCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGPR--CLCPTGYTGGSCQTLMDLCAQKPCPRNSHC--LQTGPSFHC 868 HSP 3 Score: 53.9138 bits (128), Expect = 1.161e-6 Identity = 32/126 (25.40%), Postives = 51/126 (40.48%), Query Frame = 3
Query: 549 ECENGYYPAKQCNKFCFPSENEYTC---DGFGNKICKEGLYFDADENKCLPNNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFCEFANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKC 917
ECE P + C S + C G+G C+E L ++CIA++ C C+++ +F C C +G C + C PC +C P + C C+ G++G C
Sbjct: 317 ECETQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENL-----------DDCIAAT--CAPGSTCIDRVGSFSCLCPPGRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTC 429 HSP 4 Score: 53.5286 bits (127), Expect = 1.486e-6 Identity = 40/141 (28.37%), Postives = 56/141 (39.72%), Query Frame = 3
Query: 546 HECENGYYPAKQCNKFCFPSENEYTCDGFGNKICKEGLYFDADENKCLPNNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFCEF-ANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCDLKVVQTCKCPENMRC 965
H+ NG+ QC C P GF C+E D DE + P C N G C ++ F CKC+ + G C+ + C +PC C P A+FC C +GF G C++ + C C
Sbjct: 529 HDLLNGF----QC--ICLP--------GFSGTRCEE----DIDECRSSP---------CANGGQCQDQPGAFHCKCLPGFEGPRCQTEVDECLSDPCPVGASCLDLP--GAFFCLCPSGFTGQLCEVPLCAPNLCQPKQIC 640 HSP 5 Score: 52.373 bits (124), Expect = 3.011e-6 Identity = 33/108 (30.56%), Postives = 51/108 (47.22%), Query Frame = 3
Query: 651 EGLYFDADENKCLPNNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFCEF-ANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCDLKVVQTCK--CPENMRC 965
EG + + N+C +S C N+ C + + F+C C+ +SG CE + C +PC N G+C +P A+ C C GF G +C +V + CP C
Sbjct: 506 EGQLCEVETNEC-------ASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQDQP--GAFHCKCLPGFEGPRCQTEVDECLSDPCPVGASC 604
BLAST of Jagged 2-1 vs. Ensembl Human
Match: NOTCH4 (notch receptor 4 [Source:HGNC Symbol;Acc:HGNC:7884]) HSP 1 Score: 66.2402 bits (160), Expect = 1.745e-10 Identity = 32/96 (33.33%), Postives = 45/96 (46.88%), Query Frame = 3
Query: 720 CYNNGFCVNKGSTFECKCMESYSGKFCE-FANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKC--DLKVVQTCKCPENMRCNYSESGVLFSC 998
C+N G CV+ G ++ C C + G C+ NPC PCQN C +P+G Y C C G+ G C +L Q+ C + C G +C
Sbjct: 901 CHNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSG--YLCQCAPGYDGQNCSKELDACQSQPCHNHGTCTPKPGGFHCAC 994 HSP 2 Score: 57.3806 bits (137), Expect = 8.220e-8 Identity = 35/110 (31.82%), Postives = 47/110 (42.73%), Query Frame = 3
Query: 681 KCLPNNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFCE--FANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCD--LKVVQTCKCPENMRCNYSESGVLFSC 998
+C + S C+N G CVN+ TF C C + G CE C +PC+N C P G C C TG+ G C + + CP N C ++G F C
Sbjct: 763 QCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGPR--CLCPTGYTGGSCQTLMDLCAQKPCPRNSHC--LQTGPSFHC 868 HSP 3 Score: 53.9138 bits (128), Expect = 1.161e-6 Identity = 32/126 (25.40%), Postives = 51/126 (40.48%), Query Frame = 3
Query: 549 ECENGYYPAKQCNKFCFPSENEYTC---DGFGNKICKEGLYFDADENKCLPNNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFCEFANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKC 917
ECE P + C S + C G+G C+E L ++CIA++ C C+++ +F C C +G C + C PC +C P + C C+ G++G C
Sbjct: 317 ECETQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENL-----------DDCIAAT--CAPGSTCIDRVGSFSCLCPPGRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTC 429 HSP 4 Score: 53.5286 bits (127), Expect = 1.486e-6 Identity = 40/141 (28.37%), Postives = 56/141 (39.72%), Query Frame = 3
Query: 546 HECENGYYPAKQCNKFCFPSENEYTCDGFGNKICKEGLYFDADENKCLPNNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFCEF-ANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCDLKVVQTCKCPENMRC 965
H+ NG+ QC C P GF C+E D DE + P C N G C ++ F CKC+ + G C+ + C +PC C P A+FC C +GF G C++ + C C
Sbjct: 529 HDLLNGF----QC--ICLP--------GFSGTRCEE----DIDECRSSP---------CANGGQCQDQPGAFHCKCLPGFEGPRCQTEVDECLSDPCPVGASCLDLP--GAFFCLCPSGFTGQLCEVPLCAPNLCQPKQIC 640 HSP 5 Score: 52.373 bits (124), Expect = 3.011e-6 Identity = 33/108 (30.56%), Postives = 51/108 (47.22%), Query Frame = 3
Query: 651 EGLYFDADENKCLPNNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFCEF-ANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCDLKVVQTCK--CPENMRC 965
EG + + N+C +S C N+ C + + F+C C+ +SG CE + C +PC N G+C +P A+ C C GF G +C +V + CP C
Sbjct: 506 EGQLCEVETNEC-------ASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQDQP--GAFHCKCLPGFEGPRCQTEVDECLSDPCPVGASC 604
BLAST of Jagged 2-1 vs. Ensembl Celegans
Match: clec-78 (C-type LECtin [Source:UniProtKB/TrEMBL;Acc:Q20531]) HSP 1 Score: 64.3142 bits (155), Expect = 2.495e-10 Identity = 50/143 (34.97%), Postives = 66/143 (46.15%), Query Frame = 3
Query: 549 ECENGYYPAKQC--NKFCFPSENEYTCDGFGNKICKEGLYFDADENKCLPNNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFCEFANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCDLKVVQ--TCKCPENMRC 965
E +NG AK C N FC +Y C +C G+ E+ PN CI C+N G C + GS EC C S++GK CEF N C+N GKC + G C C GF G++C+ + + T CP C
Sbjct: 2396 EQDNGSCAAKPCRNNGFCVSLVADYFC------VCPPGVSGKNCESA--PNRCIGQP--CHNGGECGDFGSHLECACPASFTGKGCEFKNTGCKT-CENGGKC-AEAAGGLQKCECSPGFTGERCETNIDECSTAHCPSGATC 2526 HSP 2 Score: 56.6102 bits (135), Expect = 5.683e-8 Identity = 48/164 (29.27%), Postives = 71/164 (43.29%), Query Frame = 3
Query: 441 INFSHKTINLKKISSKDTFELHSITLENFVKVTVEHECENGYYPAKQCNKFCFPSENEYTCDGFGNKI---CKEGLYFDADENKCLPNNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFCEF-ANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCD 920
INF T+ + E + T ++E C +P K C EN C F ++ CK G D +C + S+ CYN G C G+T++C C + ++G C+F ++ C C N G C P + C CRTGFAG +C+
Sbjct: 1980 INFYQPTVG-----QQSCIECSNTTATQTTGESLESSC----FPIDCSAKMC---ENNAECSVFMHRAQCHCKPGYVGD----RCEMLEDVCSTQPCYNGGKCEQVGTTYKCTCPKMFNGARCQFESDECNGVKCPNGGVCHDLPGVKSTTCLCRTGFAGPQCE 2127 HSP 3 Score: 53.9138 bits (128), Expect = 3.980e-7 Identity = 42/133 (31.58%), Postives = 56/133 (42.11%), Query Frame = 3
Query: 600 PSENEYTCDGFGNK---ICKEGLYFDADENKCLPNNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFCEFA-NPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCDLKVVQTCKCPENMRCNYSESGV 986
P N+ C G +CK G KC +N ++ C NNGFCV+ + + C C SGK CE A N C PC N G+C G+ C C F G C+ K C +C + G+
Sbjct: 2368 PCLNDAQCVDMGGAYKCVCKSGW----TGPKCEQDNGSCAAKPCRNNGFCVSLVADYFCVCPPGVSGKNCESAPNRCIGQPCHNGGEC--GDFGSHLECACPASFTGKGCEFKNTGCKTCENGGKCAEAAGGL 2494 HSP 4 Score: 52.373 bits (124), Expect = 1.435e-6 Identity = 33/119 (27.73%), Postives = 54/119 (45.38%), Query Frame = 3
Query: 600 PSENEYTC-DGFGNKICKEGLYFDADENKCLPNNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFCEF-ANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCDLKVVQTCKCP 950
P +N+ C D +C+ ++ + L ++C C+NN C N G+T+ C C + G CE + C N C +G + N + C C+ G+ G +CD+K Q P
Sbjct: 2252 PCQNDAKCIDEINGYMCECADGYEGVHCQHLVDHCAKQP--CHNNATCTNMGATYHCDCTLGFDGVHCEMNIDECAENQCDKLGTESCRDAVNDFKCVCKPGYTGPRCDVKQDQCADSP 2368 HSP 5 Score: 50.447 bits (119), Expect = 5.492e-6 Identity = 40/142 (28.17%), Postives = 60/142 (42.25%), Query Frame = 3
Query: 585 NKFCFPSENEYTCD---GFGNKICKEGLYFDADENKCLPNNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFCEF-ANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCDLKVVQTCKCPENMRCNYSESGVLFSC 998
N C N+Y C+ GF K C EN C + C+ +G C++K + +C C ++G+ C+ + C +PCQN KC + NG Y C C G+ G C V K P + + G + C
Sbjct: 2181 NATCVDLINDYKCECPTGFSGKRCH------IKENLCASSPCV--------HGLCIDKLYSRQCLCQPGWTGENCDQNIDECAASPCQNDAKCIDEING--YMCECADGYEGVHCQHLVDHCAKQPCHNNATCTNMGATYHC 2306
BLAST of Jagged 2-1 vs. Ensembl Celegans
Match: lin-12 (pep chromosome:WBcel235:III:9060096:9071760:-1 gene:WBGene00003001.1 transcript:R107.8.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:lin-12) HSP 1 Score: 56.225 bits (134), Expect = 7.343e-8 Identity = 33/91 (36.26%), Postives = 48/91 (52.75%), Query Frame = 3
Query: 651 EGLYFDADENKCLPNNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFC-EFANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCD 920
EG+ + D+N+CL N C NNG CVN +F C C + GK+C E N C C+N G C + + ++ C C+ GF G +C+
Sbjct: 358 EGILCEQDKNECLSEN------MCLNNGTCVNLPGSFRCDCARGFGGKWCDEPLNMCQDFHCENDGTC-MHTSDHSPVCQCKNGFIGKRCE 441
BLAST of Jagged 2-1 vs. Ensembl Celegans
Match: ZC116.3 (Probable cubilin [Source:UniProtKB/Swiss-Prot;Acc:Q20911]) HSP 1 Score: 55.4546 bits (132), Expect = 1.523e-7 Identity = 39/113 (34.51%), Postives = 57/113 (50.44%), Query Frame = 3
Query: 597 FPSENEYTC---DGF-GNKICKEGLYFDADENKCLPNNCIASSIQCYNNGFCVNKGST-FECKCMESYSGKFCEFANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCD 920
+ + +YTC DG+ G+ I +EG A N C +NC+ N G C T ++C+C + GKFCE +PC NPC+N G C N+ +C+C F G C+
Sbjct: 410 YSAVGDYTCYCPDGYVGDGIGEEGCVKSA-SNVCQNHNCV-------NAGKCKPTSDTEYKCECEAGFLGKFCEKTSPCQTNPCKNGGTCIAVE--NSAYCDCPEHFFGRACE 512
BLAST of Jagged 2-1 vs. Ensembl Celegans
Match: egas-3 (EGF plus ASC domain ion channel [Source:UniProtKB/TrEMBL;Acc:Q9XTS9]) HSP 1 Score: 54.299 bits (129), Expect = 2.453e-7 Identity = 48/154 (31.17%), Postives = 67/154 (43.51%), Query Frame = 3
Query: 579 QCNKFCFPSENEYTCDGFGNKICKEGLYFDADENKCLPNNCIASSIQC---YNNGFCVNKGST----FECKCMESYSGKFCE--FANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCDL-KVVQTCKCPENMRCNYSESGVLFSCTSIN 1010
C K C +EY K+ + ++A E + PN C +S C +G C+N S F C C ++G CE A+ C PNPC N G C + N Y C+C GF+GD C+ K C C + +G F C +N
Sbjct: 278 DCKKSCGGDSSEYC-----GKVNSRCIVYEAGEMETDPNACEDNSTLCGAELGHGMCINWQSDVTDGFACICEPLWTGPDCENPVASACTPNPCVN-GTCVLNEQYNKYKCDCDDGFSGDNCEYSKTCTAATCLYGGTCTETNNGG-FKCDCLN 424
BLAST of Jagged 2-1 vs. Ensembl Celegans
Match: cdh-4 (Cadherin-4 [Source:UniProtKB/TrEMBL;Acc:A0A1C3NSI5]) HSP 1 Score: 53.9138 bits (128), Expect = 4.691e-7 Identity = 27/73 (36.99%), Postives = 38/73 (52.05%), Query Frame = 3
Query: 714 IQCYNNGFCVNKG-STFECKCMESYSGKFCEF-ANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCDLK 926
+ C + G C+++G S F+C+C YSG CE PC +PC +C P N Y C C GF G C+ +
Sbjct: 3936 LPCQHAGTCISQGKSHFKCECPSRYSGNVCEIDLEPCASSPCPTGIQCI--PFYNDYLCKCPNGFTGKHCEAR 4006
BLAST of Jagged 2-1 vs. Ensembl Fly
Match: ft (gene:FBgn0001075 transcript:FBtr0077478) HSP 1 Score: 77.0258 bits (188), Expect = 4.468e-14 Identity = 46/139 (33.09%), Postives = 69/139 (49.64%), Query Frame = 3
Query: 609 NEYTC---DGFGNKICKEGLYFDADENKCLPNNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFCE--FANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCDLKVVQTCK---CPENMRCNYSESGVLFSCT 1001
++Y+C GF + C ++ CLPN C S +QC GS F+C C + GK CE ++ C+ PC+N G C P+G++YFC CR GF G++C+ V +C+ C C + G +CT
Sbjct: 3995 HDYSCQCTSGFSGEQCSR------RQDPCLPNPC-HSQVQCRR------LGSDFQCMCPANRDGKHCEKERSDVCYSKPCRNGGSCQRSPDGSSYFCLCRPGFRGNQCE-SVSDSCRPNPCLHGGLCVSLKPGYKCNCT 4119
BLAST of Jagged 2-1 vs. Ensembl Fly
Match: eys (gene:FBgn0031414 transcript:FBtr0344662) HSP 1 Score: 62.7734 bits (151), Expect = 1.111e-9 Identity = 36/99 (36.36%), Postives = 49/99 (49.49%), Query Frame = 3
Query: 720 CYNNGFCVNKGSTFECKCMESYSGKFCEF-ANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCDLKVVQTCKCPENMRCNYS-----ESGVLFSC 998
C N G CV+ + + C C E +SG CE + C NPCQN G C + NG Y C C+ G+ G C+L V C+ RC + G+ F+C
Sbjct: 191 CQNGGTCVDGVAYYNCTCPEGFSGSNCEENVDECMSNPCQNGGLCRDRTNG--YICTCQPGYLGSHCELDVA-VCETGTGARCQHGGECIEGPGLEFTC 286 HSP 2 Score: 51.6026 bits (122), Expect = 3.024e-6 Identity = 47/156 (30.13%), Postives = 65/156 (41.67%), Query Frame = 3
Query: 552 CENGYYPAKQCNKFCFPSEN-EYTCD---GFGNKICKEGLYFDADENKCLPNNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFC-EFANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCDLKVVQTCKCPENMRCNYSESGV-LFSCT 1001
CE G Q C E+TCD G+ +IC+E + N C +S C N G CV+K + + C C Y+G C E C NPCQN C ++ C C + G+KC+ + + P M GV FSC+
Sbjct: 262 CETGTGARCQHGGECIEGPGLEFTCDCPAGWHGRICQEEI-----------NECASSP--CQNGGVCVDKLAAYACACPMGYTGINCEEEILICADNPCQNNALCLMEE--GVPTCYCVPDYHGEKCEFQYDECQLGPRCMNGGVCIDGVDTFSCS 402
BLAST of Jagged 2-1 vs. Ensembl Fly
Match: eys (gene:FBgn0031414 transcript:FBtr0344663) HSP 1 Score: 62.7734 bits (151), Expect = 1.111e-9 Identity = 36/99 (36.36%), Postives = 49/99 (49.49%), Query Frame = 3
Query: 720 CYNNGFCVNKGSTFECKCMESYSGKFCEF-ANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCDLKVVQTCKCPENMRCNYS-----ESGVLFSC 998
C N G CV+ + + C C E +SG CE + C NPCQN G C + NG Y C C+ G+ G C+L V C+ RC + G+ F+C
Sbjct: 191 CQNGGTCVDGVAYYNCTCPEGFSGSNCEENVDECMSNPCQNGGLCRDRTNG--YICTCQPGYLGSHCELDVA-VCETGTGARCQHGGECIEGPGLEFTC 286 HSP 2 Score: 51.6026 bits (122), Expect = 3.024e-6 Identity = 47/156 (30.13%), Postives = 65/156 (41.67%), Query Frame = 3
Query: 552 CENGYYPAKQCNKFCFPSEN-EYTCD---GFGNKICKEGLYFDADENKCLPNNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFC-EFANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCDLKVVQTCKCPENMRCNYSESGV-LFSCT 1001
CE G Q C E+TCD G+ +IC+E + N C +S C N G CV+K + + C C Y+G C E C NPCQN C ++ C C + G+KC+ + + P M GV FSC+
Sbjct: 262 CETGTGARCQHGGECIEGPGLEFTCDCPAGWHGRICQEEI-----------NECASSP--CQNGGVCVDKLAAYACACPMGYTGINCEEEILICADNPCQNNALCLMEE--GVPTCYCVPDYHGEKCEFQYDECQLGPRCMNGGVCIDGVDTFSCS 402
BLAST of Jagged 2-1 vs. Ensembl Fly
Match: N (gene:FBgn0004647 transcript:FBtr0304659) HSP 1 Score: 58.151 bits (139), Expect = 2.917e-8 Identity = 55/166 (33.13%), Postives = 75/166 (45.18%), Query Frame = 3
Query: 549 ECENGYYPA------KQCNKFCFPSENEYTC-DGFGNKICK-----EGLYFDADENKCLPNNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFCEF-ANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCDLKV--VQTCKCPENMRCNYSESGVLFSCT 1001
EC G+Y A +C P NE C DG IC G + D ++C SS C + G C +K + F C+CM Y+G+ CE + C NPC N G C K NG Y C C+ F G C+ K+ + +C +C S + + FSCT
Sbjct: 740 ECPRGFYDAHCLSDVDECASN--PCVNEGRCEDGINEFICHCPPGYTGKRCELDIDEC-------SSNPCQHGGTCYDKLNAFSCQCMPGYTGQKCETNIDDCVTNPCGNGGTCIDKVNG--YKCVCKVPFTGRDCESKMDPCASNRCKNEAKCTPSSNFLDFSCT 894 HSP 2 Score: 56.9954 bits (136), Expect = 6.436e-8 Identity = 38/113 (33.63%), Postives = 50/113 (44.25%), Query Frame = 3
Query: 654 GLYFDADENKCLPNNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFCEF-ANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCDLKV--VQTCKCPENMRCNYSESG 983
G+ + +++ C P C+NNG C+++ FEC C + G CE N C NPC N G N Y CNCR G G C+ KV C CN +SG
Sbjct: 1253 GIICEINKDDCKPG-------ACHNNGSCIDRVGGFECVCQPGFVGARCEGDINECLSNPCSNAGTLDCVQLVNNYHCNCRPGHMGRHCEHKVDFCAQSPCQNGGNCNIRQSG 1358 HSP 3 Score: 54.299 bits (129), Expect = 4.075e-7 Identity = 29/68 (42.65%), Postives = 38/68 (55.88%), Query Frame = 3
Query: 720 CYNNGFCVNKGSTFECKCMESYSGKFCEFA-NPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCD 920
C G CVN +++C C Y+GK C+ PC P+PCQN G C + NG +Y C C GF G C+
Sbjct: 226 CKYGGTCVNTHGSYQCMCPTGYTGKDCDTKYKPCSPSPCQNGGIC--RSNGLSYECKCPKGFEGKNCE 291 HSP 4 Score: 52.373 bits (124), Expect = 1.398e-6 Identity = 28/71 (39.44%), Postives = 38/71 (53.52%), Query Frame = 3
Query: 720 CYNNGFCVNKGSTFECKCMESYSGKFCEF-ANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCDLKV 929
C N G C++ TF C CM ++G CE + C NPC N G C K NG + C+C GF G +C + +
Sbjct: 497 CQNEGSCLDDPGTFRCVCMPGFTGTQCEIDIDECQSNPCLNDGTCHDKING--FKCSCALGFTGARCQINI 565 HSP 5 Score: 50.0618 bits (118), Expect = 8.189e-6 Identity = 34/99 (34.34%), Postives = 47/99 (47.47%), Query Frame = 3
Query: 645 CKEGLYFDADENKC---LPNNCIASSIQCYNNGFCVNKG-STFECKCMESYSGKFCEFANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCDLKV 929
CK L FD E+ C +PN C + C N G C K + C C Y+G+ CE N C +PC+N C +++ C+C GF GD C +
Sbjct: 124 CKCPLGFD--ESLCEIAVPNAC--DHVTCLNGGTCQLKTLEEYTCACANGYTGERCETKNLCASSPCRNGATCTALAGSSSFTCSCPPGFTGDTCSYDI 218
BLAST of Jagged 2-1 vs. Ensembl Fly
Match: N (gene:FBgn0004647 transcript:FBtr0070507) HSP 1 Score: 58.151 bits (139), Expect = 2.917e-8 Identity = 55/166 (33.13%), Postives = 75/166 (45.18%), Query Frame = 3
Query: 549 ECENGYYPA------KQCNKFCFPSENEYTC-DGFGNKICK-----EGLYFDADENKCLPNNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFCEF-ANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCDLKV--VQTCKCPENMRCNYSESGVLFSCT 1001
EC G+Y A +C P NE C DG IC G + D ++C SS C + G C +K + F C+CM Y+G+ CE + C NPC N G C K NG Y C C+ F G C+ K+ + +C +C S + + FSCT
Sbjct: 740 ECPRGFYDAHCLSDVDECASN--PCVNEGRCEDGINEFICHCPPGYTGKRCELDIDEC-------SSNPCQHGGTCYDKLNAFSCQCMPGYTGQKCETNIDDCVTNPCGNGGTCIDKVNG--YKCVCKVPFTGRDCESKMDPCASNRCKNEAKCTPSSNFLDFSCT 894 HSP 2 Score: 56.9954 bits (136), Expect = 6.436e-8 Identity = 38/113 (33.63%), Postives = 50/113 (44.25%), Query Frame = 3
Query: 654 GLYFDADENKCLPNNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFCEF-ANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCDLKV--VQTCKCPENMRCNYSESG 983
G+ + +++ C P C+NNG C+++ FEC C + G CE N C NPC N G N Y CNCR G G C+ KV C CN +SG
Sbjct: 1253 GIICEINKDDCKPG-------ACHNNGSCIDRVGGFECVCQPGFVGARCEGDINECLSNPCSNAGTLDCVQLVNNYHCNCRPGHMGRHCEHKVDFCAQSPCQNGGNCNIRQSG 1358 HSP 3 Score: 54.299 bits (129), Expect = 4.075e-7 Identity = 29/68 (42.65%), Postives = 38/68 (55.88%), Query Frame = 3
Query: 720 CYNNGFCVNKGSTFECKCMESYSGKFCEFA-NPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCD 920
C G CVN +++C C Y+GK C+ PC P+PCQN G C + NG +Y C C GF G C+
Sbjct: 226 CKYGGTCVNTHGSYQCMCPTGYTGKDCDTKYKPCSPSPCQNGGIC--RSNGLSYECKCPKGFEGKNCE 291 HSP 4 Score: 52.373 bits (124), Expect = 1.398e-6 Identity = 28/71 (39.44%), Postives = 38/71 (53.52%), Query Frame = 3
Query: 720 CYNNGFCVNKGSTFECKCMESYSGKFCEF-ANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCDLKV 929
C N G C++ TF C CM ++G CE + C NPC N G C K NG + C+C GF G +C + +
Sbjct: 497 CQNEGSCLDDPGTFRCVCMPGFTGTQCEIDIDECQSNPCLNDGTCHDKING--FKCSCALGFTGARCQINI 565 HSP 5 Score: 50.0618 bits (118), Expect = 8.189e-6 Identity = 34/99 (34.34%), Postives = 47/99 (47.47%), Query Frame = 3
Query: 645 CKEGLYFDADENKC---LPNNCIASSIQCYNNGFCVNKG-STFECKCMESYSGKFCEFANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCDLKV 929
CK L FD E+ C +PN C + C N G C K + C C Y+G+ CE N C +PC+N C +++ C+C GF GD C +
Sbjct: 124 CKCPLGFD--ESLCEIAVPNAC--DHVTCLNGGTCQLKTLEEYTCACANGYTGERCETKNLCASSPCRNGATCTALAGSSSFTCSCPPGFTGDTCSYDI 218
BLAST of Jagged 2-1 vs. Ensembl Zebrafish
Match: svep1 (sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 [Source:ZFIN;Acc:ZDB-GENE-110726-1]) HSP 1 Score: 65.855 bits (159), Expect = 1.738e-10 Identity = 44/117 (37.61%), Postives = 59/117 (50.43%), Query Frame = 3
Query: 600 PSENEYTC-DGFGNKICK-----EGLYFDADENKCLPNNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFCEF-ANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCDLKV 929
P +N C DG G+ C+ GL +A+ N+C SS C N G CV++ + F C C + ++G CE N C +PCQN G C K YFC C GF GD C++ V
Sbjct: 1240 PCQNGGLCRDGMGDFQCQCQPGFVGLLCEAEVNEC-------SSSPCLNEGICVDEVNYFSCSCPDGFTGPRCEMEINECASSPCQNEGVC--KDLEGGYFCTCAQGFTGDNCEVDV 1347 HSP 2 Score: 53.5286 bits (127), Expect = 9.680e-7 Identity = 47/163 (28.83%), Postives = 69/163 (42.33%), Query Frame = 3
Query: 600 PSENEYTCDGFG-NKICK-----EGLYFDADENKCLPNNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFCEF-ANPCFPNPCQNMGKCFIKPNGNAYF-CNCRTGFAGDKCDLKV--VQTCKCPENMRCNYSESGVLFSCT-SINEDNRENPENPLYEKP 1055
P +N+ TC+ G +C G ++D ++C S C N G C + F+C+C + G CE N C +PC N G C + N YF C+C GF G +C++++ + C C E G +C DN E N Y P
Sbjct: 1202 PCQNQGTCEEVGVGYVCTCLPGFTGAKCESDIDEC-------DSAPCQNGGLCRDGMGDFQCQCQPGFVGLLCEAEVNECSSSPCLNEGICVDEVN---YFSCSCPDGFTGPRCEMEINECASSPCQNEGVCKDLEGGYFCTCAQGFTGDNCEVDVNECYSAP 1354
BLAST of Jagged 2-1 vs. Ensembl Zebrafish
Match: fat1a (FAT atypical cadherin 1a [Source:ZFIN;Acc:ZDB-GENE-050425-1]) HSP 1 Score: 65.4698 bits (158), Expect = 1.844e-10 Identity = 43/139 (30.94%), Postives = 58/139 (41.73%), Query Frame = 3
Query: 600 PSENEYTCDGF--GNKICKEGLYFDADENKCLPNNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFCEFANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCDLKVVQTCKCPENMRCNYSESGVLFSCTSIN 1010
P N TC G CK F + + C +S C G C+ +G F C+C YSG+ C+ C NPC+N GKC +G C C GF G++C V + K P + + FSC N
Sbjct: 4022 PCTNGGTCLALPNGGYFCKCTAAFMGTHCEVTISPC--ASNPCLYGGTCIPRGGDFYCQCRGQYSGQRCQLGPYCTDNPCKNSGKCIDSLDGPV--CECEPGFQGERCLSDVDECLKNPCGNGGHCQNTYGSFSCNCSN 4156
BLAST of Jagged 2-1 vs. Ensembl Zebrafish
Match: fat1a (FAT atypical cadherin 1a [Source:ZFIN;Acc:ZDB-GENE-050425-1]) HSP 1 Score: 65.4698 bits (158), Expect = 1.844e-10 Identity = 43/139 (30.94%), Postives = 58/139 (41.73%), Query Frame = 3
Query: 600 PSENEYTCDGF--GNKICKEGLYFDADENKCLPNNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFCEFANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCDLKVVQTCKCPENMRCNYSESGVLFSCTSIN 1010
P N TC G CK F + + C +S C G C+ +G F C+C YSG+ C+ C NPC+N GKC +G C C GF G++C V + K P + + FSC N
Sbjct: 4025 PCTNGGTCLALPNGGYFCKCTAAFMGTHCEVTISPC--ASNPCLYGGTCIPRGGDFYCQCRGQYSGQRCQLGPYCTDNPCKNSGKCIDSLDGPV--CECEPGFQGERCLSDVDECLKNPCGNGGHCQNTYGSFSCNCSN 4159
BLAST of Jagged 2-1 vs. Ensembl Zebrafish
Match: fat1a (FAT atypical cadherin 1a [Source:ZFIN;Acc:ZDB-GENE-050425-1]) HSP 1 Score: 65.4698 bits (158), Expect = 1.859e-10 Identity = 43/139 (30.94%), Postives = 58/139 (41.73%), Query Frame = 3
Query: 600 PSENEYTCDGF--GNKICKEGLYFDADENKCLPNNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFCEFANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCDLKVVQTCKCPENMRCNYSESGVLFSCTSIN 1010
P N TC G CK F + + C +S C G C+ +G F C+C YSG+ C+ C NPC+N GKC +G C C GF G++C V + K P + + FSC N
Sbjct: 4025 PCTNGGTCLALPNGGYFCKCTAAFMGTHCEVTISPC--ASNPCLYGGTCIPRGGDFYCQCRGQYSGQRCQLGPYCTDNPCKNSGKCIDSLDGPV--CECEPGFQGERCLSDVDECLKNPCGNGGHCQNTYGSFSCNCSN 4159
BLAST of Jagged 2-1 vs. Ensembl Zebrafish
Match: LO018022.1 (FAT atypical cadherin 4 [Source:NCBI gene;Acc:101882648]) HSP 1 Score: 62.7734 bits (151), Expect = 1.396e-9 Identity = 39/115 (33.91%), Postives = 54/115 (46.96%), Query Frame = 3
Query: 615 YTCD---GFGNKICKEGLYFDADENKCLPNNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFCEF-ANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCDLKVVQTCKC 947
Y C+ G+ +C + D ++C P C+N G C N F C C + ++G CE N C NPCQN C P G + C C++GFAG CD V+ C+C
Sbjct: 3401 YACNCRPGYAGALC------ETDIDECQPT-------PCHNGGTCHNLVGGFSCTCPDGFTGMACERDVNECLSNPCQNGALCQNYPGG--FNCLCKSGFAGKACD-SVINYCEC 3499 HSP 2 Score: 51.2174 bits (121), Expect = 5.001e-6 Identity = 37/104 (35.58%), Postives = 46/104 (44.23%), Query Frame = 3
Query: 618 TC-DGFGNKICKEGLYFDADENKCLPNNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFCE-FANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCDL 923
TC DGF C+ D N+CL N C N C N F C C ++GK C+ N C NPC N G C + G Y+C+C G G C+L
Sbjct: 3442 TCPDGFTGMACER------DVNECLSN-------PCQNGALCQNYPGGFNCLCKSGFAGKACDSVINYCECNPCFNGGSCQNRVEG--YYCHCPFGVFGKHCEL 3530
BLAST of Jagged 2-1 vs. Ensembl Xenopus
Match: fto (FTO alpha-ketoglutarate dependent dioxygenase [Source:Xenbase;Acc:XB-GENE-972564]) HSP 1 Score: 64.6994 bits (156), Expect = 5.397e-10 Identity = 45/136 (33.09%), Postives = 60/136 (44.12%), Query Frame = 3
Query: 525 FVKVTVEHECENGYYPAKQCNKFCFPSENEYTCDGFGNKICKEGLYFDADENKCLPNNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFCEFA-NPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCDLKV 929
F+ C NG C P+EN+YTC GL + D N+C P C N G C N ++ C+C Y+G+ CE PC P+PC N G C + + AY CNC GF G C+ +
Sbjct: 121 FIDACASQPCANG--------STCIPNENQYTCSCQAGYT---GLKCEVDVNECGPPG------MCKNGGTCENLPGSYRCQCHPGYTGQRCESPFIPCSPSPCMNGGTCR-QTSEFAYECNCLPGFDGKNCETNI 238 HSP 2 Score: 58.9214 bits (141), Expect = 2.787e-8 Identity = 41/114 (35.96%), Postives = 58/114 (50.88%), Query Frame = 3
Query: 600 PSENEYTC-DGFGNKICK-----EGLYFDADENKCLPNNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFCEF-ANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCD 920
P +N+ TC D G C +G++ + + N+CL N C+ NNG CV+K + F C C ++G C+ + C PCQN KC P+G Y C C TGF G C+
Sbjct: 440 PCQNDATCLDKIGGFTCLCMPGYKGIHCEIEINECLSNPCV-------NNGECVDKVNRFVCICPPGFTGSVCQIDIDDCSSTPCQNGAKCVDHPSG--YDCICATGFTGVLCE 544 HSP 3 Score: 51.9878 bits (123), Expect = 4.182e-6 Identity = 42/144 (29.17%), Postives = 62/144 (43.06%), Query Frame = 3
Query: 600 PSENEYTCDGFGNKI---CKEGL-----YFDADENKCLPNNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFCE-FANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCDLKVVQ--TCKCPENMRCNYSESGVLFSC 998
P +N TCD N CK+G D DE +S C N+G C + + + C C Y+G C+ PC P PC N G C + ++ C C TG+ G +C + + + T C RC ++ G + C
Sbjct: 741 PCQNGGTCDNLVNGYRCSCKKGFKGYNCQIDIDE---------CASNPCLNHGTCRDGINGYTCHCGLPYTGTNCQNILTPCSPEPCHNGGICQESEDFKSFSCLCATGWHGQRCTIDIDECITNPCKNYGRCQNTKGGYICHC 875 HSP 4 Score: 50.8322 bits (120), Expect = 8.468e-6 Identity = 32/113 (28.32%), Postives = 49/113 (43.36%), Query Frame = 3
Query: 585 NKFCFPSENEYTCDGFGNKICKEGLYFDADENKCLPNNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFCEF-ANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCD 920
N C P C +C+E + + C P+ + C+N G C++K + C+C+ ++G+ CE N C NPC G N Y C C+ GF G C+
Sbjct: 1163 NGICLPGYQGVNC-----PLCEENI------DDCAPS---SEGPHCFNGGRCLDKIGGYSCECLPGFAGERCEGDVNECLSNPCSAKGSLDCIQLDNNYLCKCKPGFTGRHCE 1261
BLAST of Jagged 2-1 vs. Ensembl Xenopus
Match: fto (FTO alpha-ketoglutarate dependent dioxygenase [Source:Xenbase;Acc:XB-GENE-972564]) HSP 1 Score: 64.3142 bits (155), Expect = 5.862e-10 Identity = 45/136 (33.09%), Postives = 60/136 (44.12%), Query Frame = 3
Query: 525 FVKVTVEHECENGYYPAKQCNKFCFPSENEYTCDGFGNKICKEGLYFDADENKCLPNNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFCEFA-NPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCDLKV 929
F+ C NG C P+EN+YTC GL + D N+C P C N G C N ++ C+C Y+G+ CE PC P+PC N G C + + AY CNC GF G C+ +
Sbjct: 125 FIDACASQPCANG--------STCIPNENQYTCSCQAGYT---GLKCEVDVNECGPPG------MCKNGGTCENLPGSYRCQCHPGYTGQRCESPFIPCSPSPCMNGGTCR-QTSEFAYECNCLPGFDGKNCETNI 242 HSP 2 Score: 58.9214 bits (141), Expect = 2.879e-8 Identity = 41/114 (35.96%), Postives = 58/114 (50.88%), Query Frame = 3
Query: 600 PSENEYTC-DGFGNKICK-----EGLYFDADENKCLPNNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFCEF-ANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCD 920
P +N+ TC D G C +G++ + + N+CL N C+ NNG CV+K + F C C ++G C+ + C PCQN KC P+G Y C C TGF G C+
Sbjct: 444 PCQNDATCLDKIGGFTCLCMPGYKGIHCEIEINECLSNPCV-------NNGECVDKVNRFVCICPPGFTGSVCQIDIDDCSSTPCQNGAKCVDHPSG--YDCICATGFTGVLCE 548 HSP 3 Score: 55.4546 bits (132), Expect = 2.917e-7 Identity = 29/83 (34.94%), Postives = 42/83 (50.60%), Query Frame = 3
Query: 699 CIASSIQCYNNGFCV--NKGSTFECKCMESYSGKFCEFANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCDLKVVQTC 941
C +S C N G C+ + GS + CKC +++ GK+C+ NPC C N G C + + + C C GF G+ C V C
Sbjct: 9 CRGASEPCLNEGKCITNDDGSAY-CKCTDAFVGKYCQLQNPCQETICLNGGTCKVSSDLSKGVCTCAPGFGGENCKQPVANVC 90 HSP 4 Score: 51.9878 bits (123), Expect = 3.410e-6 Identity = 35/118 (29.66%), Postives = 54/118 (45.76%), Query Frame = 3
Query: 654 GLYFDADENKCLPNNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFCE-FANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCDLKVVQ--TCKCPENMRCNYSESGVLFSC 998
G + D+N+CL N C N G C N + + C C + + G C+ PC P PC N G C + ++ C C TG+ G +C + + + T C RC ++ G + C
Sbjct: 694 GKKCEVDKNECLSN-------PCQNGGTCDNLVNGYRCSCKKGFKGTNCQNILTPCSPEPCHNGGICQESEDFKSFSCLCATGWHGQRCTIDIDECITNPCKNYGRCQNTKGGYICHC 804 HSP 5 Score: 51.2174 bits (121), Expect = 6.080e-6 Identity = 56/189 (29.63%), Postives = 77/189 (40.74%), Query Frame = 3
Query: 390 MDTNLSISIKLENGGSTINFSHKTINLKKISSKDTFELHSITLENFVKVTVEHECENGYYPAKQCNKFCFPSEN--EYTCDGFGNKICKEGLY-----FDADENKCLPNNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFCEF-ANPCFPNPCQNMGKCFIKPNG-NAYFCNCRTGFAGDKCDLKV 929
+D N +S +NGG+ N +N + S K F+ +N + C NG C SE+ ++C +C G + D DE C+ N C N G C N + C C E ++G CE + C NPCQN C +G N + CNC GF GDKC V
Sbjct: 699 VDKNECLSNPCQNGGTCDNL----VNGYRCSCKKGFK--GTNCQNILTPCSPEPCHNG--------GICQESEDFKSFSC------LCATGWHGQRCTIDIDE--CITN-------PCKNYGRCQNTKGGYICHCFEGFNGVNCENNIDDCLSNPCQNGASCV---DGINTFSCNCLAGFHGDKCQKDV 855
BLAST of Jagged 2-1 vs. Ensembl Xenopus
Match: fto (FTO alpha-ketoglutarate dependent dioxygenase [Source:Xenbase;Acc:XB-GENE-972564]) HSP 1 Score: 64.3142 bits (155), Expect = 6.088e-10 Identity = 45/136 (33.09%), Postives = 60/136 (44.12%), Query Frame = 3
Query: 525 FVKVTVEHECENGYYPAKQCNKFCFPSENEYTCDGFGNKICKEGLYFDADENKCLPNNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFCEFA-NPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCDLKV 929
F+ C NG C P+EN+YTC GL + D N+C P C N G C N ++ C+C Y+G+ CE PC P+PC N G C + + AY CNC GF G C+ +
Sbjct: 125 FIDACASQPCANG--------STCIPNENQYTCSCQAGYT---GLKCEVDVNECGPPG------MCKNGGTCENLPGSYRCQCHPGYTGQRCESPFIPCSPSPCMNGGTCR-QTSEFAYECNCLPGFDGKNCETNI 242 HSP 2 Score: 58.9214 bits (141), Expect = 2.936e-8 Identity = 41/114 (35.96%), Postives = 58/114 (50.88%), Query Frame = 3
Query: 600 PSENEYTC-DGFGNKICK-----EGLYFDADENKCLPNNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFCEF-ANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCD 920
P +N+ TC D G C +G++ + + N+CL N C+ NNG CV+K + F C C ++G C+ + C PCQN KC P+G Y C C TGF G C+
Sbjct: 445 PCQNDATCLDKIGGFTCLCMPGYKGIHCEIEINECLSNPCV-------NNGECVDKVNRFVCICPPGFTGSVCQIDIDDCSSTPCQNGAKCVDHPSG--YDCICATGFTGVLCE 549 HSP 3 Score: 51.6026 bits (122), Expect = 4.557e-6 Identity = 42/144 (29.17%), Postives = 62/144 (43.06%), Query Frame = 3
Query: 600 PSENEYTCDGFGNKI---CKEGL-----YFDADENKCLPNNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFCE-FANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCDLKVVQ--TCKCPENMRCNYSESGVLFSC 998
P +N TCD N CK+G D DE +S C N+G C + + + C C Y+G C+ PC P PC N G C + ++ C C TG+ G +C + + + T C RC ++ G + C
Sbjct: 745 PCQNGGTCDNLVNGYRCSCKKGFKGYNCQIDIDE---------CASNPCLNHGTCRDGINGYTCHCGLPYTGTNCQNILTPCSPEPCHNGGICQESEDFKSFSCLCATGWHGQRCTIDIDECITNPCKNYGRCQNTKGGYICHC 879 HSP 4 Score: 50.8322 bits (120), Expect = 8.332e-6 Identity = 37/142 (26.06%), Postives = 59/142 (41.55%), Query Frame = 3
Query: 507 SITLENFVKVTVEHECENGYYPAKQCNKFCFPSENEYTCD---GFGNKICKEGLYFDADENKCLPNNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFCEF-ANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCD 920
I L + V E+E + C N++ C G +C+E + + C P+ + C+N G C++K + C+C+ ++G+ CE N C NPC G N Y C C+ GF G C+
Sbjct: 1147 GICLPGYQGVNCEYEIDECQIQPCHNGGTCVDLVNQFRCSCPPGTRGPLCEENI------DDCAPS---SEGPHCFNGGRCLDKIGGYSCECLPGFAGERCEGDVNECLSNPCSAKGSLDCIQLDNNYLCKCKPGFTGRHCE 1279
BLAST of Jagged 2-1 vs. Ensembl Xenopus
Match: fto (FTO alpha-ketoglutarate dependent dioxygenase [Source:Xenbase;Acc:XB-GENE-972564]) HSP 1 Score: 64.3142 bits (155), Expect = 6.565e-10 Identity = 45/136 (33.09%), Postives = 60/136 (44.12%), Query Frame = 3
Query: 525 FVKVTVEHECENGYYPAKQCNKFCFPSENEYTCDGFGNKICKEGLYFDADENKCLPNNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFCEFA-NPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCDLKV 929
F+ C NG C P+EN+YTC GL + D N+C P C N G C N ++ C+C Y+G+ CE PC P+PC N G C + + AY CNC GF G C+ +
Sbjct: 147 FIDACASQPCANG--------STCIPNENQYTCSCQAGYT---GLKCEVDVNECGPPG------MCKNGGTCENLPGSYRCQCHPGYTGQRCESPFIPCSPSPCMNGGTCR-QTSEFAYECNCLPGFDGKNCETNI 264 HSP 2 Score: 58.5362 bits (140), Expect = 3.332e-8 Identity = 41/114 (35.96%), Postives = 58/114 (50.88%), Query Frame = 3
Query: 600 PSENEYTC-DGFGNKICK-----EGLYFDADENKCLPNNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFCEF-ANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCD 920
P +N+ TC D G C +G++ + + N+CL N C+ NNG CV+K + F C C ++G C+ + C PCQN KC P+G Y C C TGF G C+
Sbjct: 466 PCQNDATCLDKIGGFTCLCMPGYKGIHCEIEINECLSNPCV-------NNGECVDKVNRFVCICPPGFTGSVCQIDIDDCSSTPCQNGAKCVDHPSG--YDCICATGFTGVLCE 570 HSP 3 Score: 51.6026 bits (122), Expect = 5.041e-6 Identity = 42/144 (29.17%), Postives = 62/144 (43.06%), Query Frame = 3
Query: 600 PSENEYTCDGFGNKI---CKEGL-----YFDADENKCLPNNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFCE-FANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCDLKVVQ--TCKCPENMRCNYSESGVLFSC 998
P +N TCD N CK+G D DE +S C N+G C + + + C C Y+G C+ PC P PC N G C + ++ C C TG+ G +C + + + T C RC ++ G + C
Sbjct: 767 PCQNGGTCDNLVNGYRCSCKKGFKGYNCQIDIDE---------CASNPCLNHGTCRDGINGYTCHCGLPYTGTNCQNILTPCSPEPCHNGGICQESEDFKSFSCLCATGWHGQRCTIDIDECITNPCKNYGRCQNTKGGYICHC 901
BLAST of Jagged 2-1 vs. Ensembl Xenopus
Match: fto (FTO alpha-ketoglutarate dependent dioxygenase [Source:Xenbase;Acc:XB-GENE-972564]) HSP 1 Score: 63.929 bits (154), Expect = 7.466e-10 Identity = 45/136 (33.09%), Postives = 60/136 (44.12%), Query Frame = 3
Query: 525 FVKVTVEHECENGYYPAKQCNKFCFPSENEYTCDGFGNKICKEGLYFDADENKCLPNNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFCEFA-NPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCDLKV 929
F+ C NG C P+EN+YTC GL + D N+C P C N G C N ++ C+C Y+G+ CE PC P+PC N G C + + AY CNC GF G C+ +
Sbjct: 128 FIDACASQPCANG--------STCIPNENQYTCSCQAGYT---GLKCEVDVNECGPPG------MCKNGGTCENLPGSYRCQCHPGYTGQRCESPFIPCSPSPCMNGGTCR-QTSEFAYECNCLPGFDGKNCETNI 245 HSP 2 Score: 58.5362 bits (140), Expect = 3.724e-8 Identity = 41/114 (35.96%), Postives = 58/114 (50.88%), Query Frame = 3
Query: 600 PSENEYTC-DGFGNKICK-----EGLYFDADENKCLPNNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFCEF-ANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCD 920
P +N+ TC D G C +G++ + + N+CL N C+ NNG CV+K + F C C ++G C+ + C PCQN KC P+G Y C C TGF G C+
Sbjct: 448 PCQNDATCLDKIGGFTCLCMPGYKGIHCEIEINECLSNPCV-------NNGECVDKVNRFVCICPPGFTGSVCQIDIDDCSSTPCQNGAKCVDHPSG--YDCICATGFTGVLCE 552 HSP 3 Score: 51.6026 bits (122), Expect = 5.682e-6 Identity = 42/144 (29.17%), Postives = 62/144 (43.06%), Query Frame = 3
Query: 600 PSENEYTCDGFGNKI---CKEGL-----YFDADENKCLPNNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFCE-FANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCDLKVVQ--TCKCPENMRCNYSESGVLFSC 998
P +N TCD N CK+G D DE +S C N+G C + + + C C Y+G C+ PC P PC N G C + ++ C C TG+ G +C + + + T C RC ++ G + C
Sbjct: 748 PCQNGGTCDNLVNGYRCSCKKGFKGYNCQIDIDE---------CASNPCLNHGTCRDGINGYTCHCGLPYTGTNCQNILTPCSPEPCHNGGICQESEDFKSFSCLCATGWHGQRCTIDIDECITNPCKNYGRCQNTKGGYICHC 882
BLAST of Jagged 2-1 vs. Ensembl Mouse
Match: Notch4 (notch 4 [Source:MGI Symbol;Acc:MGI:107471]) HSP 1 Score: 68.5514 bits (166), Expect = 2.505e-11 Identity = 34/97 (35.05%), Postives = 49/97 (50.52%), Query Frame = 3
Query: 720 CYNNGFCVNKGSTFECKCMESYSGKFCE-FANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCDLKVVQTCK---CPENMRCNYSESGVLFSC 998
C N G C++ GS++ C+C + GK C+ NPC PNPC + C +P+G Y C C G+ G C KV+ C+ C + C G +C
Sbjct: 897 CQNGGLCIDTGSSYFCRCPPGFQGKLCQDNVNPCEPNPCHHGSTCVPQPSG--YVCQCAPGYEGQNCS-KVLDACQSQPCHNHGTCTSRPGGFHCAC 990 HSP 2 Score: 58.9214 bits (141), Expect = 2.187e-8 Identity = 39/107 (36.45%), Postives = 51/107 (47.66%), Query Frame = 3
Query: 693 NNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFC-EFANP-CFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCDLKVVQTCK---CPENMRCNYSESGVLFSC 998
++C+++S C N G CVNK TF C C + G C E NP C +PC+N C P G C C G+ G C ++ C CP RC +SG F C
Sbjct: 766 DHCVSAS--CLNGGTCVNKPGTFFCLCATGFQGLHCEEKTNPSCADSPCRNKATCQDTPRGAR--CLCSPGYTGSSCQ-TLIDLCARKPCPHTARC--LQSGPSFQC 865 HSP 3 Score: 54.6842 bits (130), Expect = 4.772e-7 Identity = 31/98 (31.63%), Postives = 44/98 (44.90%), Query Frame = 3
Query: 720 CYNNGFCVNKGSTFECKCMESYSGKFCEFA-NPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCDLKVVQTCK---CPENMRCNYSESGVLFSCT 1001
C N G C + + C C+ S++G+ C+ A + C C N G C KP +FC C TGF G C+ K +C C C + G C+
Sbjct: 735 CLNGGSCSIRPEGYSCTCLPSHTGRHCQTAVDHCVSASCLNGGTCVNKP--GTFFCLCATGFQGLHCEEKTNPSCADSPCRNKATCQDTPRGARCLCS 830 HSP 4 Score: 53.5286 bits (127), Expect = 9.754e-7 Identity = 34/103 (33.01%), Postives = 45/103 (43.69%), Query Frame = 3
Query: 666 DADENKCLPNNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFCEF-ANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKC--DLKVVQTCKCPENMRC 965
+AD N+CL S C+ C++ +TF C C G+ CE N C NPC N C NG + C C GF G +C D+ + C RC
Sbjct: 470 EADHNECL-------SQPCHPGSTCLDLLATFHCLCPPGLEGRLCEVEVNECTSNPCLNQAACHDLLNG--FQCLCLPGFTGARCEKDMDECSSTPCANGGRC 563 HSP 5 Score: 53.1434 bits (126), Expect = 1.207e-6 Identity = 29/85 (34.12%), Postives = 40/85 (47.06%), Query Frame = 3
Query: 708 SSIQCYNNGFCVNKGSTFECKCMESYSGKFCEF-ANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCDLKVVQTCKCPENM 959
SS C N G C ++ F C+C+ + G CE + C +PC C P A+FC CR GF G C++ + C NM
Sbjct: 553 SSTPCANGGRCRDQPGAFYCECLPGFEGPHCEKEVDECLSDPCPVGASCLDLP--GAFFCLCRPGFTGQLCEVPL-----CTPNM 630 HSP 6 Score: 50.447 bits (119), Expect = 7.844e-6 Identity = 30/105 (28.57%), Postives = 43/105 (40.95%), Query Frame = 3
Query: 720 CYNNGFCVNKGSTFECKCMESYSGKFCEFANPC----------FPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCDLKV--VQTCKCPENMRCNYSESGVLFSC 998
C + C+ G +F+C C++ ++G C+F C CQN G C G++YFC C GF G C V + C C SG + C
Sbjct: 850 CPHTARCLQSGPSFQCLCLQGWTGALCDFPLSCQKAAMSQGIEISGLCQNGGLCI--DTGSSYFCRCPPGFQGKLCQDNVNPCEPNPCHHGSTCVPQPSGYVCQC 952
BLAST of Jagged 2-1 vs. Ensembl Mouse
Match: Notch3 (notch 3 [Source:MGI Symbol;Acc:MGI:99460]) HSP 1 Score: 64.6994 bits (156), Expect = 3.704e-10 Identity = 36/107 (33.64%), Postives = 50/107 (46.73%), Query Frame = 3
Query: 654 GLYFDADENKCLPNNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFCEF-ANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCDLKV--VQTCKCPENMRC 965
G + + D C P++C +N G CV+ S+F C C Y+G C++ A+PCF PC + G C P + C CR GF G +C V C RC
Sbjct: 919 GFHCEIDLPDCSPSSC-------FNGGTCVDGVSSFSCLCRPGYTGTHCQYEADPCFSRPCLHGGIC--NPTHPGFECTCREGFTGSQCQNPVDWCSQAPCQNGGRC 1016 HSP 2 Score: 60.4622 bits (145), Expect = 7.629e-9 Identity = 38/117 (32.48%), Postives = 52/117 (44.44%), Query Frame = 3
Query: 600 PSENEYTC-DGFGNKICK-----EGLYFDADENKCLPNNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFCEF-ANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCDLKV 929
P N+ TC D G C G Y + D ++C S C N G C ++ + F C C +SG C+ + C PC+N KC +P+G Y C C GF G C+ V
Sbjct: 440 PCRNQATCLDRIGQFTCICMAGFTGTYCEVDIDEC-------QSSPCVNGGVCKDRVNGFSCTCPSGFSGSMCQLDVDECASTPCRNGAKCVDQPDG--YECRCAEGFEGTLCERNV 547 HSP 3 Score: 60.077 bits (144), Expect = 9.934e-9 Identity = 40/138 (28.99%), Postives = 60/138 (43.48%), Query Frame = 3
Query: 549 ECENGYYPAKQCNKFCFPSENEYTCD---GFGNKICKEGLYFDADENKCLPNNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFCEF-ANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCDLKVVQTCKCP 950
EC G P + + C ++ + C G+ C + D N+CL S C N C+++ F C CM ++G +CE + C +PC N G C K N + C C +GF+G C L V + P
Sbjct: 395 ECSIGANPCEHLGR-CVNTQGSFLCQCGRGYTGPRC------ETDVNECL-------SGPCRNQATCLDRIGQFTCICMAGFTGTYCEVDIDECQSSPCVNGGVC--KDRVNGFSCTCPSGFSGSMCQLDVDECASTP 516 HSP 4 Score: 56.9954 bits (136), Expect = 9.646e-8 Identity = 36/123 (29.27%), Postives = 57/123 (46.34%), Query Frame = 3
Query: 654 GLYFDADENKCLPNNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFCEF-ANPCFPNPCQ--NMGKCFIKPNGNAYFCNCRTGFAGDKCDLKV--VQTCKCPENMRCNYS---ESGVLFSC 998
G+ + +E+ C + S +QC +NG CV+ F C C Y+G CE N C P C + C P G+ + C C GF G +C + + ++ C +C +S G+ F+C
Sbjct: 1155 GVLCEINEDDCDLGPSLDSGVQCLHNGTCVDLVGGFRCNCPPGYTGLHCEADINECRPGACHAAHTRDCLQDPGGH-FRCVCHPGFTGPRCQIALSPCESQPCQHGGQCRHSLGRGGGLTFTC 1276 HSP 5 Score: 56.225 bits (134), Expect = 1.391e-7 Identity = 28/75 (37.33%), Postives = 39/75 (52.00%), Query Frame = 3
Query: 708 SSIQCYNNGFCVNKGSTFECKCMESYSGKFCEF-ANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCDLKV 929
S C + G C+N +F C+C Y+G CE PC P+PC+N G C + + Y C C GF G C++ V
Sbjct: 165 SGTTCRHGGTCLNTPGSFRCQCPLGYTGLLCENPVVPCAPSPCRNGGTCR-QSSDVTYDCACLPGFEGQNCEVNV 238 HSP 6 Score: 55.8398 bits (133), Expect = 1.922e-7 Identity = 27/78 (34.62%), Postives = 38/78 (48.72%), Query Frame = 3
Query: 720 CYNNGFCVNKGSTFECKCMESYSGKFCEF-ANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCDLKVVQTCKCP 950
C G C++KG + C C E +G CE +PC PCQ+ G C + Y C C G+AGD C+ + + P
Sbjct: 1056 CQEGGKCIDKGRSHYCVCPEGRTGSHCEHEVDPCTAQPCQHGGTC--RGYMGGYVCECPAGYAGDSCEDNIDECASQP 1131 HSP 7 Score: 53.9138 bits (128), Expect = 8.518e-7 Identity = 34/106 (32.08%), Postives = 46/106 (43.40%), Query Frame = 3
Query: 693 NNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFCEF-ANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKC--DLKVVQTCKCPENMRCNYSESGVLFSCT 1001
+ C + C + G CVN +F C+C Y+G CE N C PC+N C + + C C GF G C D+ Q+ C C +G FSCT
Sbjct: 394 DECSIGANPCEHLGRCVNTQGSFLCQCGRGYTGPRCETDVNECLSGPCRNQATCLDRI--GQFTCICMAGFTGTYCEVDIDECQSSPCVNGGVCKDRVNG--FSCT 495 HSP 8 Score: 53.1434 bits (126), Expect = 1.360e-6 Identity = 36/117 (30.77%), Postives = 55/117 (47.01%), Query Frame = 3
Query: 594 CFPSENEYTC---DGFGNKICKEGLYFDADENKCLPNNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFCEF-ANPCFPNPCQNMGKCFIKPNGNAYF-CNCRTGFAGDKCDLKV 929
C N ++C GF +C+ D DE +S C N CV++ +EC+C E + G CE + C P+PC + G+C +G A F C C G+ G +C+ +V
Sbjct: 485 CKDRVNGFSCTCPSGFSGSMCQ----LDVDE---------CASTPCRNGAKCVDQPDGYECRCAEGFEGTLCERNVDDCSPDPCHH-GRCV---DGIASFSCACAPGYTGIRCESQV 584 HSP 9 Score: 51.9878 bits (123), Expect = 2.685e-6 Identity = 28/83 (33.73%), Postives = 40/83 (48.19%), Query Frame = 3
Query: 705 ASSIQCYNNGFCVNKGSTFECKCMESYSGKFC-EFANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCDLKVVQTCKCP 950
A + C +G C N F C C Y+G FC + + C PNPC + G C + ++ C+C GFAG +C V + P
Sbjct: 816 AGASPCGPHGTCTNLPGNFRCICHRGYTGPFCDQDIDDCDPNPCLHGGSC--QDGVGSFSCSCLDGFAGPRCARDVDECLSSP 896 HSP 10 Score: 51.2174 bits (121), Expect = 4.510e-6 Identity = 34/120 (28.33%), Postives = 48/120 (40.00%), Query Frame = 3
Query: 642 ICKEGLYFDADENKCLPNNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFCEFANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCDLKVVQ-----------TC-KCPENMRC 965
+C+ G P+ C S C G C + G F C C + G CE +PC P+ C++ G C P+ C+C G+ G +C V + TC P N RC
Sbjct: 720 VCEPGWSGPRCSQSLAPDAC--ESQPCQAGGTCTSDGIGFRCTCAPGFQGHQCEVLSPCTPSLCEHGGHCESDPD-RLTVCSCPPGWQGPRCQQDVDECAGASPCGPHGTCTNLPGNFRC 836 HSP 11 Score: 50.8322 bits (120), Expect = 5.871e-6 Identity = 26/97 (26.80%), Postives = 37/97 (38.14%), Query Frame = 3
Query: 720 CYNNGFCVNKGSTFECKCMESYSGKFCEFANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCDLKV----VQTCKCPENMRCNYSESGVLFSC 998
C++ C ++ ++F C C +G C + C NPC C P C C GF G CD V + C RC ++ L C
Sbjct: 324 CFHGATCHDRVASFYCACPMGKTGLLCHLDDACVSNPCHEDAICDTNPVSGRAICTCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQC 420
BLAST of Jagged 2-1 vs. Ensembl Mouse
Match: Sned1 (sushi, nidogen and EGF-like domains 1 [Source:MGI Symbol;Acc:MGI:3045960]) HSP 1 Score: 61.2326 bits (147), Expect = 3.539e-9 Identity = 34/91 (37.36%), Postives = 42/91 (46.15%), Query Frame = 3
Query: 708 SSIQCYNNGFCVNKGSTFECKCMESYSGKFCE-----FANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCDLKVVQTCKCPENMRC 965
SS C N G CV+ + C C+E + G CE +PC NPCQN G C G Y C C GF G C +++ C C RC
Sbjct: 392 SSDPCQNGGSCVDLVGNYSCICVEPFEGPQCETGSYLVPSPCLSNPCQNGGTCVDADEG--YVCECPEGFMGLDCRERILNDCDCRNGGRC 480 HSP 2 Score: 56.225 bits (134), Expect = 1.354e-7 Identity = 38/115 (33.04%), Postives = 51/115 (44.35%), Query Frame = 3
Query: 594 CFPSENEYTCD---GFGNKICKEGLYFDADENKCLPNNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFCEFANP--CFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCDL 923
C E+ YTC+ GF + C+ K P+ C SS C N G C G + C C ++G+ CE P C PC N G CF Y C+C GF+G C++
Sbjct: 556 CDAHEDSYTCECPRGFHGRHCE----------KARPHLC--SSGPCRNGGTCKEMGDEYRCTCPYRFTGRHCEIGKPDSCASGPCHNGGTCFHYI--GKYKCDCPPGFSGRHCEI 656 HSP 3 Score: 51.6026 bits (122), Expect = 3.516e-6 Identity = 30/87 (34.48%), Postives = 42/87 (48.28%), Query Frame = 3
Query: 687 LPNNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFCEFANP--CFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCDLKVVQTC 941
LP+ C S C+N G C ++ C+C + G+ CE A P C PC+N G C K G+ Y C C F G C++ +C
Sbjct: 541 LPSPC--DSDPCFNGGSCDAHEDSYTCECPRGFHGRHCEKARPHLCSSGPCRNGGTC--KEMGDEYRCTCPYRFTGRHCEIGKPDSC 623
BLAST of Jagged 2-1 vs. Ensembl Mouse
Match: Notch2 (notch 2 [Source:MGI Symbol;Acc:MGI:97364]) HSP 1 Score: 60.077 bits (144), Expect = 9.345e-9 Identity = 41/114 (35.96%), Postives = 57/114 (50.00%), Query Frame = 3
Query: 600 PSENEYTC-DGFGNKICK-----EGLYFDADENKCLPNNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFCEF-ANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCD 920
P +N+ TC D G C +G++ + + N+C N C+ NNG CV+K + F+C C ++G C+ + C PC N KC PNG Y C C TGF G CD
Sbjct: 464 PCQNDATCLDKIGGFTCLCMPGFKGVHCELEVNECQSNPCV-------NNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTPCLNGAKCIDHPNG--YECQCATGFTGILCD 568 HSP 2 Score: 56.225 bits (134), Expect = 1.448e-7 Identity = 29/75 (38.67%), Postives = 40/75 (53.33%), Query Frame = 3
Query: 708 SSIQCYNNGFCVNKGSTFECKCMESYSGKFCE-FANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCDLKV 929
+S C N G C + S + C CM Y+GK C+ PC PNPC+N C PN ++ C C G+ G +C + V
Sbjct: 800 ASNPCLNQGTCFDDVSGYTCHCMLPYTGKNCQTVLAPCSPNPCENAAVCKEAPNFESFSCLCAPGWQGKRCTVDV 874 HSP 3 Score: 56.225 bits (134), Expect = 1.550e-7 Identity = 40/114 (35.09%), Postives = 53/114 (46.49%), Query Frame = 3
Query: 600 PSENEYTC---DGFGNKICKEGLYFDADENKCLPNNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFCEF-ANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCDLKV 929
P +Y C G+ C E D DE +A+S C + G CVN F C+C++ Y+G CE N C +PCQN C K G + C C GF G C+L+V
Sbjct: 394 PLNGQYICTCPQGYKGADCTE----DVDECA------MANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDINECHSDPCQNDATCLDKIGG--FTCLCMPGFKGVHCELEV 495 HSP 4 Score: 55.8398 bits (133), Expect = 1.717e-7 Identity = 39/104 (37.50%), Postives = 49/104 (47.12%), Query Frame = 3
Query: 642 ICKEGLYFDADENKCLP-----------NNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFC-EFANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKC 917
+CKE F++ C P + CI S C NNG C N ++ C+C +SG C E N C NPCQN G C + N + C C GF GDKC
Sbjct: 847 VCKEAPNFESFSCLCAPGWQGKRCTVDVDECI--SKPCMNNGVCHNTQGSYVCECPPGFSGMDCEEDINDCLANPCQNGGSCVD--HVNTFSCQCHPGFIGDKC 946 HSP 5 Score: 53.5286 bits (127), Expect = 1.051e-6 Identity = 47/152 (30.92%), Postives = 71/152 (46.71%), Query Frame = 3
Query: 513 TLENFVKVTVEHECENGYYPAKQCN--KFCF--PSENEYTCDGFGNKI---CKEGLY---FDADENKC-LPNNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFCEFA-NPCFPNPCQNMGKCFIKPNGNAYF-CNCRTGFAGDKCDLKV 929
T + T E C+ G+ KQC C P EN TC ++ C GL +AD N+C +P +C + G C+N ++ C+C + ++G+ C+ PC P+PC N G C + G+ F CNC GF G C+ +
Sbjct: 120 TCHMLSRDTYECTCQVGFT-GKQCQWTDACLSHPCENGSTCTSVASQFSCKCPAGLTGQKCEADINECDIPG-------RCQHGGTCLNLPGSYRCQCPQGFTGQHCDSPYVPCAPSPCVNGGTC--RQTGDFTFECNCLPGFEGSTCERNI 261
BLAST of Jagged 2-1 vs. Ensembl Mouse
Match: Fat4 (FAT atypical cadherin 4 [Source:MGI Symbol;Acc:MGI:3045256]) HSP 1 Score: 58.9214 bits (141), Expect = 2.549e-8 Identity = 34/99 (34.34%), Postives = 50/99 (50.51%), Query Frame = 3
Query: 654 GLYFDADENKCLPNNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFCEF-ANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCDLKVVQTCKC 947
G + + D ++CLP C+N G C N F C C E ++G+ CE N C P+PC++ C P G + C C+TG+ G C+ V C+C
Sbjct: 3858 GSWCEVDIDECLP-------APCHNGGTCHNLVGGFSCSCPEGFTGRACERDINECLPSPCKHGAVCQNFPGG--FNCVCKTGYTGKMCE-SSVNYCEC 3946 HSP 2 Score: 51.2174 bits (121), Expect = 5.373e-6 Identity = 34/101 (33.66%), Postives = 47/101 (46.53%), Query Frame = 3
Query: 624 DGFGNKICKEGLYFDADENKCLPNNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFCEFA-NPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCDL 923
+GF + C+ D N+CLP+ C + C N F C C Y+GK CE + N C NPC N G C + +Y+C+C G G C+L
Sbjct: 3892 EGFTGRACER------DINECLPS-------PCKHGAVCQNFPGGFNCVCKTGYTGKMCESSVNYCECNPCFNGGSC--QSGVESYYCHCPFGVFGKHCEL 3977
BLAST of Jagged 2-1 vs. UniProt/SwissProt
Match: sp|P33450|FAT_DROME (Cadherin-related tumor suppressor OS=Drosophila melanogaster OX=7227 GN=ft PE=1 SV=3) HSP 1 Score: 77.0258 bits (188), Expect = 4.478e-13 Identity = 46/139 (33.09%), Postives = 69/139 (49.64%), Query Frame = 3
Query: 609 NEYTC---DGFGNKICKEGLYFDADENKCLPNNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFCE--FANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCDLKVVQTCK---CPENMRCNYSESGVLFSCT 1001
++Y+C GF + C ++ CLPN C S +QC GS F+C C + GK CE ++ C+ PC+N G C P+G++YFC CR GF G++C+ V +C+ C C + G +CT
Sbjct: 3995 HDYSCQCTSGFSGEQCSR------RQDPCLPNPC-HSQVQCRR------LGSDFQCMCPANRDGKHCEKERSDVCYSKPCRNGGSCQRSPDGSSYFCLCRPGFRGNQCE-SVSDSCRPNPCLHGGLCVSLKPGYKCNCT 4119
BLAST of Jagged 2-1 vs. UniProt/SwissProt
Match: sp|P31695|NOTC4_MOUSE (Neurogenic locus notch homolog protein 4 OS=Mus musculus OX=10090 GN=Notch4 PE=1 SV=3) HSP 1 Score: 68.5514 bits (166), Expect = 1.752e-10 Identity = 34/97 (35.05%), Postives = 49/97 (50.52%), Query Frame = 3
Query: 720 CYNNGFCVNKGSTFECKCMESYSGKFCE-FANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCDLKVVQTCK---CPENMRCNYSESGVLFSC 998
C N G C++ GS++ C+C + GK C+ NPC PNPC + C +P+G Y C C G+ G C KV+ C+ C + C G +C
Sbjct: 897 CQNGGLCIDTGSSYFCRCPPGFQGKLCQDNVNPCEPNPCHHGSTCVPQPSG--YVCQCAPGYEGQNCS-KVLDACQSQPCHNHGTCTSRPGGFHCAC 990 HSP 2 Score: 58.9214 bits (141), Expect = 1.530e-7 Identity = 39/107 (36.45%), Postives = 51/107 (47.66%), Query Frame = 3
Query: 693 NNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFC-EFANP-CFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCDLKVVQTCK---CPENMRCNYSESGVLFSC 998
++C+++S C N G CVNK TF C C + G C E NP C +PC+N C P G C C G+ G C ++ C CP RC +SG F C
Sbjct: 766 DHCVSAS--CLNGGTCVNKPGTFFCLCATGFQGLHCEEKTNPSCADSPCRNKATCQDTPRGAR--CLCSPGYTGSSCQ-TLIDLCARKPCPHTARC--LQSGPSFQC 865 HSP 3 Score: 54.6842 bits (130), Expect = 3.338e-6 Identity = 31/98 (31.63%), Postives = 44/98 (44.90%), Query Frame = 3
Query: 720 CYNNGFCVNKGSTFECKCMESYSGKFCEFA-NPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCDLKVVQTCK---CPENMRCNYSESGVLFSCT 1001
C N G C + + C C+ S++G+ C+ A + C C N G C KP +FC C TGF G C+ K +C C C + G C+
Sbjct: 735 CLNGGSCSIRPEGYSCTCLPSHTGRHCQTAVDHCVSASCLNGGTCVNKP--GTFFCLCATGFQGLHCEEKTNPSCADSPCRNKATCQDTPRGARCLCS 830 HSP 4 Score: 53.5286 bits (127), Expect = 6.823e-6 Identity = 34/103 (33.01%), Postives = 45/103 (43.69%), Query Frame = 3
Query: 666 DADENKCLPNNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFCEF-ANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKC--DLKVVQTCKCPENMRC 965
+AD N+CL S C+ C++ +TF C C G+ CE N C NPC N C NG + C C GF G +C D+ + C RC
Sbjct: 470 EADHNECL-------SQPCHPGSTCLDLLATFHCLCPPGLEGRLCEVEVNECTSNPCLNQAACHDLLNG--FQCLCLPGFTGARCEKDMDECSSTPCANGGRC 563 HSP 5 Score: 53.1434 bits (126), Expect = 8.441e-6 Identity = 29/85 (34.12%), Postives = 40/85 (47.06%), Query Frame = 3
Query: 708 SSIQCYNNGFCVNKGSTFECKCMESYSGKFCEF-ANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCDLKVVQTCKCPENM 959
SS C N G C ++ F C+C+ + G CE + C +PC C P A+FC CR GF G C++ + C NM
Sbjct: 553 SSTPCANGGRCRDQPGAFYCECLPGFEGPHCEKEVDECLSDPCPVGASCLDLP--GAFFCLCRPGFTGQLCEVPL-----CTPNM 630
BLAST of Jagged 2-1 vs. UniProt/SwissProt
Match: sp|Q99466|NOTC4_HUMAN (Neurogenic locus notch homolog protein 4 OS=Homo sapiens OX=9606 GN=NOTCH4 PE=1 SV=2) HSP 1 Score: 66.2402 bits (160), Expect = 8.381e-10 Identity = 32/96 (33.33%), Postives = 45/96 (46.88%), Query Frame = 3
Query: 720 CYNNGFCVNKGSTFECKCMESYSGKFCE-FANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKC--DLKVVQTCKCPENMRCNYSESGVLFSC 998
C+N G CV+ G ++ C C + G C+ NPC PCQN C +P+G Y C C G+ G C +L Q+ C + C G +C
Sbjct: 901 CHNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSG--YLCQCAPGYDGQNCSKELDACQSQPCHNHGTCTPKPGGFHCAC 994 HSP 2 Score: 57.3806 bits (137), Expect = 3.948e-7 Identity = 35/110 (31.82%), Postives = 47/110 (42.73%), Query Frame = 3
Query: 681 KCLPNNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFCE--FANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCD--LKVVQTCKCPENMRCNYSESGVLFSC 998
+C + S C+N G CVN+ TF C C + G CE C +PC+N C P G C C TG+ G C + + CP N C ++G F C
Sbjct: 763 QCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGPR--CLCPTGYTGGSCQTLMDLCAQKPCPRNSHC--LQTGPSFHC 868 HSP 3 Score: 53.9138 bits (128), Expect = 5.575e-6 Identity = 32/126 (25.40%), Postives = 51/126 (40.48%), Query Frame = 3
Query: 549 ECENGYYPAKQCNKFCFPSENEYTC---DGFGNKICKEGLYFDADENKCLPNNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFCEFANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKC 917
ECE P + C S + C G+G C+E L ++CIA++ C C+++ +F C C +G C + C PC +C P + C C+ G++G C
Sbjct: 317 ECETQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENL-----------DDCIAAT--CAPGSTCIDRVGSFSCLCPPGRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTC 429 HSP 4 Score: 53.5286 bits (127), Expect = 7.136e-6 Identity = 40/141 (28.37%), Postives = 56/141 (39.72%), Query Frame = 3
Query: 546 HECENGYYPAKQCNKFCFPSENEYTCDGFGNKICKEGLYFDADENKCLPNNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFCEF-ANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCDLKVVQTCKCPENMRC 965
H+ NG+ QC C P GF C+E D DE + P C N G C ++ F CKC+ + G C+ + C +PC C P A+FC C +GF G C++ + C C
Sbjct: 529 HDLLNGF----QC--ICLP--------GFSGTRCEE----DIDECRSSP---------CANGGQCQDQPGAFHCKCLPGFEGPRCQTEVDECLSDPCPVGASCLDLP--GAFFCLCPSGFTGQLCEVPLCAPNLCQPKQIC 640
BLAST of Jagged 2-1 vs. UniProt/SwissProt
Match: sp|Q61982|NOTC3_MOUSE (Neurogenic locus notch homolog protein 3 OS=Mus musculus OX=10090 GN=Notch3 PE=1 SV=1) HSP 1 Score: 64.6994 bits (156), Expect = 2.591e-9 Identity = 36/107 (33.64%), Postives = 50/107 (46.73%), Query Frame = 3
Query: 654 GLYFDADENKCLPNNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFCEF-ANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCDLKV--VQTCKCPENMRC 965
G + + D C P++C +N G CV+ S+F C C Y+G C++ A+PCF PC + G C P + C CR GF G +C V C RC
Sbjct: 919 GFHCEIDLPDCSPSSC-------FNGGTCVDGVSSFSCLCRPGYTGTHCQYEADPCFSRPCLHGGIC--NPTHPGFECTCREGFTGSQCQNPVDWCSQAPCQNGGRC 1016 HSP 2 Score: 60.4622 bits (145), Expect = 5.336e-8 Identity = 38/117 (32.48%), Postives = 52/117 (44.44%), Query Frame = 3
Query: 600 PSENEYTC-DGFGNKICK-----EGLYFDADENKCLPNNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFCEF-ANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCDLKV 929
P N+ TC D G C G Y + D ++C S C N G C ++ + F C C +SG C+ + C PC+N KC +P+G Y C C GF G C+ V
Sbjct: 440 PCRNQATCLDRIGQFTCICMAGFTGTYCEVDIDEC-------QSSPCVNGGVCKDRVNGFSCTCPSGFSGSMCQLDVDECASTPCRNGAKCVDQPDG--YECRCAEGFEGTLCERNV 547 HSP 3 Score: 60.077 bits (144), Expect = 6.949e-8 Identity = 40/138 (28.99%), Postives = 60/138 (43.48%), Query Frame = 3
Query: 549 ECENGYYPAKQCNKFCFPSENEYTCD---GFGNKICKEGLYFDADENKCLPNNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFCEF-ANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCDLKVVQTCKCP 950
EC G P + + C ++ + C G+ C + D N+CL S C N C+++ F C CM ++G +CE + C +PC N G C K N + C C +GF+G C L V + P
Sbjct: 395 ECSIGANPCEHLGR-CVNTQGSFLCQCGRGYTGPRC------ETDVNECL-------SGPCRNQATCLDRIGQFTCICMAGFTGTYCEVDIDECQSSPCVNGGVC--KDRVNGFSCTCPSGFSGSMCQLDVDECASTP 516 HSP 4 Score: 56.9954 bits (136), Expect = 6.747e-7 Identity = 36/123 (29.27%), Postives = 57/123 (46.34%), Query Frame = 3
Query: 654 GLYFDADENKCLPNNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFCEF-ANPCFPNPCQ--NMGKCFIKPNGNAYFCNCRTGFAGDKCDLKV--VQTCKCPENMRCNYS---ESGVLFSC 998
G+ + +E+ C + S +QC +NG CV+ F C C Y+G CE N C P C + C P G+ + C C GF G +C + + ++ C +C +S G+ F+C
Sbjct: 1155 GVLCEINEDDCDLGPSLDSGVQCLHNGTCVDLVGGFRCNCPPGYTGLHCEADINECRPGACHAAHTRDCLQDPGGH-FRCVCHPGFTGPRCQIALSPCESQPCQHGGQCRHSLGRGGGLTFTC 1276 HSP 5 Score: 56.225 bits (134), Expect = 9.729e-7 Identity = 28/75 (37.33%), Postives = 39/75 (52.00%), Query Frame = 3
Query: 708 SSIQCYNNGFCVNKGSTFECKCMESYSGKFCEF-ANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCDLKV 929
S C + G C+N +F C+C Y+G CE PC P+PC+N G C + + Y C C GF G C++ V
Sbjct: 165 SGTTCRHGGTCLNTPGSFRCQCPLGYTGLLCENPVVPCAPSPCRNGGTCR-QSSDVTYDCACLPGFEGQNCEVNV 238 HSP 6 Score: 55.8398 bits (133), Expect = 1.344e-6 Identity = 27/78 (34.62%), Postives = 38/78 (48.72%), Query Frame = 3
Query: 720 CYNNGFCVNKGSTFECKCMESYSGKFCEF-ANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCDLKVVQTCKCP 950
C G C++KG + C C E +G CE +PC PCQ+ G C + Y C C G+AGD C+ + + P
Sbjct: 1056 CQEGGKCIDKGRSHYCVCPEGRTGSHCEHEVDPCTAQPCQHGGTC--RGYMGGYVCECPAGYAGDSCEDNIDECASQP 1131 HSP 7 Score: 53.9138 bits (128), Expect = 5.958e-6 Identity = 34/106 (32.08%), Postives = 46/106 (43.40%), Query Frame = 3
Query: 693 NNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFCEF-ANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKC--DLKVVQTCKCPENMRCNYSESGVLFSCT 1001
+ C + C + G CVN +F C+C Y+G CE N C PC+N C + + C C GF G C D+ Q+ C C +G FSCT
Sbjct: 394 DECSIGANPCEHLGRCVNTQGSFLCQCGRGYTGPRCETDVNECLSGPCRNQATCLDRI--GQFTCICMAGFTGTYCEVDIDECQSSPCVNGGVCKDRVNG--FSCT 495 HSP 8 Score: 53.1434 bits (126), Expect = 9.512e-6 Identity = 36/117 (30.77%), Postives = 55/117 (47.01%), Query Frame = 3
Query: 594 CFPSENEYTC---DGFGNKICKEGLYFDADENKCLPNNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFCEF-ANPCFPNPCQNMGKCFIKPNGNAYF-CNCRTGFAGDKCDLKV 929
C N ++C GF +C+ D DE +S C N CV++ +EC+C E + G CE + C P+PC + G+C +G A F C C G+ G +C+ +V
Sbjct: 485 CKDRVNGFSCTCPSGFSGSMCQ----LDVDE---------CASTPCRNGAKCVDQPDGYECRCAEGFEGTLCERNVDDCSPDPCHH-GRCV---DGIASFSCACAPGYTGIRCESQV 584
BLAST of Jagged 2-1 vs. UniProt/SwissProt
Match: sp|Q9R172|NOTC3_RAT (Neurogenic locus notch homolog protein 3 OS=Rattus norvegicus OX=10116 GN=Notch3 PE=2 SV=2) HSP 1 Score: 63.1586 bits (152), Expect = 6.789e-9 Identity = 34/107 (31.78%), Postives = 51/107 (47.66%), Query Frame = 3
Query: 654 GLYFDADENKCLPNNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFCEF-ANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCDLKV--VQTCKCPENMRC 965
G + + D C P++C +N G CV+ ++F C C Y+G C++ +PCF PC + G C P + + C CR GF G++C V C RC
Sbjct: 920 GFHCETDLLDCSPSSC-------FNGGTCVDGVNSFSCLCRPGYTGTHCQYKVDPCFSRPCLHGGIC--NPTHSGFECTCREGFTGNQCQNPVDWCSQAPCQNGGRC 1017 HSP 2 Score: 61.2326 bits (147), Expect = 2.609e-8 Identity = 41/138 (29.71%), Postives = 60/138 (43.48%), Query Frame = 3
Query: 549 ECENGYYPAKQCNKFCFPSENEYTCD---GFGNKICKEGLYFDADENKCLPNNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFCEF-ANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCDLKVVQTCKCP 950
EC G P + + C ++ + C G+ C + D N+CL S C N C+++ F C CM ++G FCE + C +PC N G C K N + C C +GF+G C L V + P
Sbjct: 396 ECSIGANPCEHLGR-CVNTQGSFLCQCGRGYTGPRC------ETDVNECL-------SGPCRNQATCLDRIGQFTCICMAGFTGTFCEVDIDECQSSPCVNGGVC--KDRVNGFSCTCPSGFSGSTCQLDVDECASTP 517 HSP 3 Score: 58.151 bits (139), Expect = 2.601e-7 Identity = 37/117 (31.62%), Postives = 52/117 (44.44%), Query Frame = 3
Query: 600 PSENEYTC-DGFGNKICK-----EGLYFDADENKCLPNNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFCEF-ANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCDLKV 929
P N+ TC D G C G + + D ++C S C N G C ++ + F C C +SG C+ + C PC+N KC +P+G Y C C GF G C+ V
Sbjct: 441 PCRNQATCLDRIGQFTCICMAGFTGTFCEVDIDEC-------QSSPCVNGGVCKDRVNGFSCTCPSGFSGSTCQLDVDECASTPCRNGAKCVDQPDG--YECRCAEGFEGTLCERNV 548 HSP 4 Score: 54.6842 bits (130), Expect = 2.724e-6 Identity = 36/123 (29.27%), Postives = 56/123 (45.53%), Query Frame = 3
Query: 654 GLYFDADENKCLPNNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFCEF-ANPCFPNPCQ--NMGKCFIKPNGNAYFCNCRTGFAGDKCDLKV--VQTCKCPENMRCNYS---ESGVLFSC 998
G+ + +E+ C P + S ++C +NG CV+ F C C Y+G CE N C P C + C P G+ + C C GF G +C + ++ C +C S G+ F+C
Sbjct: 1156 GVLCEINEDDCGPGPSLDSGLRCLHNGTCVDLVGGFRCNCPPGYTGLHCEADINECRPGTCHAAHTRDCLQDPGGH-FRCICLPGFTGPRCQTALFPCESQPCQHGGQCRPSLGRGGGLTFTC 1277 HSP 5 Score: 54.6842 bits (130), Expect = 2.941e-6 Identity = 29/83 (34.94%), Postives = 42/83 (50.60%), Query Frame = 3
Query: 705 ASSIQCYNNGFCVNKGSTFECKCMESYSGKFC-EFANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCDLKVVQTCKCP 950
A + C +G C N +F C C Y+G FC + + C PNPC N G C + ++ C+C +GFAG +C V + P
Sbjct: 817 AGASPCGPHGTCTNLPGSFRCICHGGYTGPFCDQDIDDCDPNPCLNGGSC--QDGVGSFSCSCLSGFAGPRCARDVDECLSSP 897 HSP 6 Score: 54.6842 bits (130), Expect = 3.257e-6 Identity = 37/113 (32.74%), Postives = 52/113 (46.02%), Query Frame = 3
Query: 603 SENEYTC---DGFGNKICKEGLYFDADENKCLPNNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFCEFA-NPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCDLKV 929
S+ Y C G+ + C+ D DE C A + C + G C+N +F C C Y+G CE PC P+PC+N G C + + Y C C GF G C++ V
Sbjct: 140 SDGRYACACPPGYQGRNCRS----DIDE-------CRAGA-SCRHGGTCINTPGSFHCLCPLGYTGLLCENPIVPCAPSPCRNGGTCR-QSSDVTYDCACLPGFEGQNCEVNV 239 HSP 7 Score: 53.1434 bits (126), Expect = 8.663e-6 Identity = 34/106 (32.08%), Postives = 46/106 (43.40%), Query Frame = 3
Query: 693 NNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFCEF-ANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKC--DLKVVQTCKCPENMRCNYSESGVLFSCT 1001
+ C + C + G CVN +F C+C Y+G CE N C PC+N C + + C C GF G C D+ Q+ C C +G FSCT
Sbjct: 395 DECSIGANPCEHLGRCVNTQGSFLCQCGRGYTGPRCETDVNECLSGPCRNQATCLDRI--GQFTCICMAGFTGTFCEVDIDECQSSPCVNGGVCKDRVNG--FSCT 496
BLAST of Jagged 2-1 vs. TrEMBL
Match: I1ZIA3 (Jagged 2-1 (Fragment) OS=Schmidtea mediterranea OX=79327 PE=2 SV=1) HSP 1 Score: 311.612 bits (797), Expect = 5.535e-100 Identity = 159/186 (85.48%), Postives = 159/186 (85.48%), Query Frame = 3
Query: 99 MLTLRVSLAHILIALLFFGFSYSLHITQANFNSQQSPAKVNLRFLISKFSQLLTSEPVKFSLCIDKNHEKCFWTTNKNVELHEELFQEVQFEFYINNMDTNLSISIKLENGGSTINFSHKTINLKKISSKDTFELHSITLENFVKVTVEHECENGYYPAKQCNKFCFPSENEYTCDGFGNKICKEG 656
MLTLRVSLAHILIALLFFGFSYSLHITQANFNSQQSPAKVNLR CFWTTNKNVELHEELFQEVQFEFYINNMDTNLSISIKLENGGSTINFSHKTINLKKISSKDTFELHSITLENFVKVTVEHECENGYYPAKQCNKFCFPSENEYTCDGFGNKICKEG
Sbjct: 1 MLTLRVSLAHILIALLFFGFSYSLHITQANFNSQQSPAKVNLR---------------------------CFWTTNKNVELHEELFQEVQFEFYINNMDTNLSISIKLENGGSTINFSHKTINLKKISSKDTFELHSITLENFVKVTVEHECENGYYPAKQCNKFCFPSENEYTCDGFGNKICKEG 159
BLAST of Jagged 2-1 vs. TrEMBL
Match: A0A1Z1R174 (Jagged-like (Fragment) OS=Schmidtea mediterranea OX=79327 PE=2 SV=1) HSP 1 Score: 111.694 bits (278), Expect = 3.985e-22 Identity = 112/421 (26.60%), Postives = 182/421 (43.23%), Query Frame = 3
Query: 198 QQSPAKVNLRFLISKFSQLLTSEPVKFSL--CIDKNH---EKCFW---TTNKNVELHEELFQEVQFEFYINNMDTNLSISIKLENGGSTINFSHKTINLKKISSKDTFELHSITLENFVKVTVEH--ECENGYYPAKQCNKFCFPSENEYTCDGFGNKICKEGLYFDADENKCLPNNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFCEFANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCDLKVVQTC---KCPENMRCNY------------SESGV---LFSCTSINEDNRENP---------ENPLYEK-PIKKSENK--QNQNWNNVSSTTTIVAA-----IGCFMVLISIGVSVYVCQRTRNYS--SLIKSRTSEGTQSNFLNQYPPKFESTFKRSFSLEDNSAYL 1319
+++P + L+ + + + K+ L C+ E+C W T N N H+ + F ++N+ + L + I KT N K I ++ + I ++F ++V+ +C+ G++P +C CF + Y CD G KIC G FD NKC +NC + +I C+NNG CV+ +C C++ +SG CE +PC C+N GKC N + C C+ + G C+ K ++C C +N C S+S + + SI P + P+ E P+ K N+ Q+ + N +TT IV IGCF V + Y ++++ YS S + S S + + E F+R SL+DNS YL
Sbjct: 20 KRAPGTLTLKIQTPAYVEDCVEKYCKYVLKSCVGSGRSENERCLWSPLTVNSNY-FHKMPKYLAEISFEVDNVKDPFYFNANLSYFQNEILV--KTENFKNIIIQNLYGASQIHSQDFATLSVDIVIKCKPGFFPKNRCLVSCFEEASVYKCDENGRKICLSGYVFDPLTNKCNLDNCNSENIICFNNGTCVSGAHNPKCFCVDGFSGPSCEIWDPCTKPRCKNGGKCIKSELKNDFICFCKNNYYGKNCE-KTGKSCNDITCEKNQFCEIVNNQPKCSVKKNSKSFIQKTFVTPPSIKSTTITKPKFVSLNVETKKPIVESIPVNKGTNRLLQSHSLLNEYTTTAIVIVLVVFMIGCFGVTFWVLKIKYFQKKSKTYSNFSTLPVMPSIYNASTYRSS-----EENFRRWHSLDDNSFYL 431
BLAST of Jagged 2-1 vs. TrEMBL
Match: V3ZTS2 (Uncharacterized protein (Fragment) OS=Lottia gigantea OX=225164 GN=LOTGIDRAFT_202917 PE=4 SV=1) HSP 1 Score: 78.5666 bits (192), Expect = 6.503e-13 Identity = 49/140 (35.00%), Postives = 66/140 (47.14%), Query Frame = 3
Query: 513 TLENFVKVTVEHECENGYYPAKQCNKFCFPSENEYTC---DGFGNKICKEGLYFDADENKCLPNNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFCE-FANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCD 920
T + + + C+N N FC PS + C DG+ C+ N CLPN C NNGFC G++F C C Y+G C+ ANPC PNPCQN G F +P+G ++ C C+ G+ G C
Sbjct: 34 TCQTIANPCLPNPCKN--------NGFCQPSGTSFLCTCQDGYAGTTCQT------IANPCLPN-------PCKNNGFCQPSGTSFLCTCQAGYAGTTCQTIANPCLPNPCQNNG--FCQPSGTSFLCTCQAGYTGTTCQ 150 HSP 2 Score: 75.8702 bits (185), Expect = 5.396e-12 Identity = 48/142 (33.80%), Postives = 65/142 (45.77%), Query Frame = 3
Query: 507 SITLENFVKVTVEHECENGYYPAKQCNKFCFPSENEYTCD---GFGNKICKEGLYFDADENKCLPNNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFCE-FANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCD 920
T + + + C+N N FC PS + C G+ C+ N CLPN C NNGFC G++F C C Y+G C+ ANPC PNPCQN G F +P+G ++ C C+ G+ G C
Sbjct: 70 GTTCQTIANPCLPNPCKN--------NGFCQPSGTSFLCTCQAGYAGTTCQT------IANPCLPN-------PCQNNGFCQPSGTSFLCTCQAGYTGTTCQTIANPCLPNPCQNNG--FCQPSGTSFLCTCQAGYTGTTCQ 188 HSP 3 Score: 68.1662 bits (165), Expect = 2.156e-9 Identity = 52/169 (30.77%), Postives = 73/169 (43.20%), Query Frame = 3
Query: 702 IASSIQCYNNGFCVNKGSTFECKCMESYSGKFCE-FANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCDLKVVQTC---KCPENMRCNYSESGVLFSCTSINEDNR-ENPENPLYEKPIKKSENKQNQNWNNVSSTTTIVAAIGCFMVLISIGVSVYVCQRTRN 1193
+ S C NNGFC G++F C C Y+G C+ ANPC PNPC+N G F +P+G ++ C C+ G+AG C + C C N C S + L +C + + NP P QN + S T+ F+ G + CQ N
Sbjct: 3 LCSPNPCQNNGFCQPSGTSFSCTCQGGYTGSTCQTIANPCLPNPCKNNG--FCQPSGTSFLCTCQDGYAGTTCQ-TIANPCLPNPCKNNGFCQPSGTSFLCTCQAGYAGTTCQTIANPCLPNPC------QNNGFCQPSGTS--------FLCTCQAGYTGTTCQTIAN 154
BLAST of Jagged 2-1 vs. TrEMBL
Match: A0A267FSM0 (Delta-like protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig014459g1 PE=4 SV=1) HSP 1 Score: 82.8037 bits (203), Expect = 1.051e-12 Identity = 66/222 (29.73%), Postives = 104/222 (46.85%), Query Frame = 3
Query: 297 NHEKCFWTTNKNVELHEELFQEVQFEFYI----NNMDTNLSISIKLENGGST----INFSHKTINLKKISSKDTFELHSITLENFVKVTVEHECENGYYPAKQCNKFCFPSEN----EYTCDGFGNKICKEGLYFDADENKCLPNNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFCE-FANPC-FPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCD 920
+H + W +K+V F ++ I +N D L I + + + ST I+ T+ +KD + S + + +++ + C +GYY A CN +C N YTC G K+C+ G + AD P+ C S+ C N CV G ++ C+C YSG CE F NPC + NPC+N C + NG++Y C C ++G C+
Sbjct: 77 DHSQSGWYWDKDVIDFGSDFAGIKNPVVIAMNFDNNDGRLFIRVIVHDKDSTADDLIDIFSATLEASGPDAKD-LTIVSHAMGHTLRIRYWYSCHSGYYGA-LCNTYCMEKNNAWDGHYTCGSDGQKVCRSG-WIGADCKT--PHPC--STDVCQNGATCVPNGDSYSCRCPADYSGTNCETFLNPCTYRNPCKNGATCVL--NGDSYSCRCPADYSGTNCE 289
BLAST of Jagged 2-1 vs. TrEMBL
Match: A0A267E305 (Delta-like protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig020206g1 PE=4 SV=1) HSP 1 Score: 82.4185 bits (202), Expect = 1.241e-12 Identity = 66/222 (29.73%), Postives = 104/222 (46.85%), Query Frame = 3
Query: 297 NHEKCFWTTNKNVELHEELFQEVQFEFYI----NNMDTNLSISIKLENGGST----INFSHKTINLKKISSKDTFELHSITLENFVKVTVEHECENGYYPAKQCNKFCFPSEN----EYTCDGFGNKICKEGLYFDADENKCLPNNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFCE-FANPC-FPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCD 920
+H + W +K+V F ++ I +N D L I + + + ST I+ T+ +KD + S + + +++ + C +GYY A CN +C N YTC G K+C+ G + AD P+ C S+ C N CV G ++ C+C YSG CE F NPC + NPC+N C + NG++Y C C ++G C+
Sbjct: 77 DHSQSGWYWDKDVIDFGSDFAGIKNPVVIAMNFDNNDGRLFIRVIVHDKDSTADDLIDIFSATLEASGPDAKD-LTIVSHAMGHTLRIRYWYSCHSGYYGA-LCNTYCMEKNNAWDGHYTCGSDGQKVCRSG-WIGADCKT--PHPC--STGVCQNGATCVPNGDSYSCRCPADYSGTNCETFLNPCTYRNPCKNGATCVL--NGDSYSCRCPADYSGTNCE 289 HSP 2 Score: 61.2326 bits (147), Expect = 5.591e-6 Identity = 67/237 (28.27%), Postives = 99/237 (41.77%), Query Frame = 3
Query: 720 CYNNGFC-VNKGSTF-ECKCMESYSGKFCEFANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCDLKVVQTCK---CPENMRCNYSESGVLFSCTSINEDNRENPENPLYEKPIKKSENKQNQNWNNVSS--TTTIVAAIGC---FMVLISIGV--SVYVCQRTRNYSSLIKSRTSEGTQSNFLNQYPPKFESTFKR---SFSLEDNSAYLPVNSTVLTNSP--QLITLGSSN 1379
C N+G C VN+ C C E + G+ CE NPC+ +PCQN C + + + C+C F GD+C+ C C C G FSCT E + KS + +N + S+ ++ + A GC F++LI++GV VY+ +R RN S +S G + N +F T + + ED A S + P QL G N
Sbjct: 378 CLNSGICHVNETDGVPRCLCPEGFLGENCEIDNPCYSSPCQNGAPC--RNSAVGFACDCPPDFIGDRCETAKPNYCASGPCRNGGDCVSGTDG--FSCTCPTGFKGALCER-FASEGTPKSVGQVGENPGDASTGNSSVVGVAAGCAVGFLLLIALGVFLGVYLLRRRRNAGSEADLGSSIGHTNEIYNN-ASEFTGTVRSYDPTVQWEDEPAVYEAISGLPVGEPANQLPVGGLEN 608
BLAST of Jagged 2-1 vs. Ensembl Cavefish
Match: fat1a (protocadherin Fat 1 [Source:NCBI gene;Acc:103021730]) HSP 1 Score: 69.707 bits (169), Expect = 9.164e-12 Identity = 48/147 (32.65%), Postives = 62/147 (42.18%), Query Frame = 3
Query: 570 PAKQCNKFCFPSENEYTCDGF--GNKICKEGLYFDADENKCLPNNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFCEFANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCDLKVVQTCK--CPENMRCNYSESGVLFSC 998
PA C P N TC G CK F + + C SS C G CV +G F C+C YSG+ C+ C NPC+N G+C +G C C GF GD+C V + K C +C+ + FSC
Sbjct: 4030 PAPACTSN--PCTNGGTCAELPNGGYFCKCSALFMGTHCEVSISPC--SSNPCLYGGTCVPRGDDFYCQCRGQYSGQRCQLGPYCTENPCKNSGRCIDSLDGPV--CECEPGFQGDRCLGDVDECVKNPCANGGQCHNTYGS--FSC 4168
BLAST of Jagged 2-1 vs. Ensembl Cavefish
Match: fat1a (protocadherin Fat 1 [Source:NCBI gene;Acc:103021730]) HSP 1 Score: 69.707 bits (169), Expect = 9.564e-12 Identity = 48/147 (32.65%), Postives = 62/147 (42.18%), Query Frame = 3
Query: 570 PAKQCNKFCFPSENEYTCDGF--GNKICKEGLYFDADENKCLPNNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFCEFANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCDLKVVQTCK--CPENMRCNYSESGVLFSC 998
PA C P N TC G CK F + + C SS C G CV +G F C+C YSG+ C+ C NPC+N G+C +G C C GF GD+C V + K C +C+ + FSC
Sbjct: 4053 PAPACTSN--PCTNGGTCAELPNGGYFCKCSALFMGTHCEVSISPC--SSNPCLYGGTCVPRGDDFYCQCRGQYSGQRCQLGPYCTENPCKNSGRCIDSLDGPV--CECEPGFQGDRCLGDVDECVKNPCANGGQCHNTYGS--FSC 4191
BLAST of Jagged 2-1 vs. Ensembl Cavefish
Match: fat1a (protocadherin Fat 1 [Source:NCBI gene;Acc:103021730]) HSP 1 Score: 69.707 bits (169), Expect = 9.566e-12 Identity = 48/147 (32.65%), Postives = 62/147 (42.18%), Query Frame = 3
Query: 570 PAKQCNKFCFPSENEYTCDGF--GNKICKEGLYFDADENKCLPNNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFCEFANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCDLKVVQTCK--CPENMRCNYSESGVLFSC 998
PA C P N TC G CK F + + C SS C G CV +G F C+C YSG+ C+ C NPC+N G+C +G C C GF GD+C V + K C +C+ + FSC
Sbjct: 4053 PAPACTSN--PCTNGGTCAELPNGGYFCKCSALFMGTHCEVSISPC--SSNPCLYGGTCVPRGDDFYCQCRGQYSGQRCQLGPYCTENPCKNSGRCIDSLDGPV--CECEPGFQGDRCLGDVDECVKNPCANGGQCHNTYGS--FSC 4191
BLAST of Jagged 2-1 vs. Ensembl Cavefish
Match: fat1a (protocadherin Fat 1 [Source:NCBI gene;Acc:103021730]) HSP 1 Score: 69.707 bits (169), Expect = 9.566e-12 Identity = 48/147 (32.65%), Postives = 62/147 (42.18%), Query Frame = 3
Query: 570 PAKQCNKFCFPSENEYTCDGF--GNKICKEGLYFDADENKCLPNNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFCEFANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCDLKVVQTCK--CPENMRCNYSESGVLFSC 998
PA C P N TC G CK F + + C SS C G CV +G F C+C YSG+ C+ C NPC+N G+C +G C C GF GD+C V + K C +C+ + FSC
Sbjct: 4053 PAPACTSN--PCTNGGTCAELPNGGYFCKCSALFMGTHCEVSISPC--SSNPCLYGGTCVPRGDDFYCQCRGQYSGQRCQLGPYCTENPCKNSGRCIDSLDGPV--CECEPGFQGDRCLGDVDECVKNPCANGGQCHNTYGS--FSC 4191
BLAST of Jagged 2-1 vs. Ensembl Cavefish
Match: fat1a (protocadherin Fat 1 [Source:NCBI gene;Acc:103021730]) HSP 1 Score: 69.707 bits (169), Expect = 9.618e-12 Identity = 48/147 (32.65%), Postives = 62/147 (42.18%), Query Frame = 3
Query: 570 PAKQCNKFCFPSENEYTCDGF--GNKICKEGLYFDADENKCLPNNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFCEFANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCDLKVVQTCK--CPENMRCNYSESGVLFSC 998
PA C P N TC G CK F + + C SS C G CV +G F C+C YSG+ C+ C NPC+N G+C +G C C GF GD+C V + K C +C+ + FSC
Sbjct: 4053 PAPACTSN--PCTNGGTCAELPNGGYFCKCSALFMGTHCEVSISPC--SSNPCLYGGTCVPRGDDFYCQCRGQYSGQRCQLGPYCTENPCKNSGRCIDSLDGPV--CECEPGFQGDRCLGDVDECVKNPCANGGQCHNTYGS--FSC 4191
BLAST of Jagged 2-1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004043.1 (pep scaffold:Pmarinus_7.0:GL479143:9150:31231:-1 gene:ENSPMAG00000003698.1 transcript:ENSPMAT00000004043.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 67.781 bits (164), Expect = 7.064e-12 Identity = 40/118 (33.90%), Postives = 56/118 (47.46%), Query Frame = 3
Query: 654 GLYFDADENKCLPNNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFCEF-ANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCDLKV--VQTCKCPENMRCNYSESGVLFSC 998
G + +AD ++CL S C + G C N F C+C+ +SG CE + C PCQN G C G A C+C GF+G CD+ V + C N C + +G +SC
Sbjct: 1525 GTWCEADMDECL-------STPCRHGGSCQNLPGGFACRCLPGFSGTACETDVDECLEGPCQNGGLCHNTQGGFA--CDCSAGFSGKICDVTVDNCASSPCYNNGSCVNTATG--YSC 1631 HSP 2 Score: 57.7658 bits (138), Expect = 8.377e-9 Identity = 32/100 (32.00%), Postives = 42/100 (42.00%), Query Frame = 3
Query: 627 GFGNKICKEGLYFDADENKCLPNNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFCEFA-NPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCDL 923
GF C + D ++CL C N G C N F C C +SGK C+ + C +PC N G C G Y C C G +G +C+L
Sbjct: 1560 GFSGTAC------ETDVDECLEG-------PCQNGGLCHNTQGGFACDCSAGFSGKICDVTVDNCASSPCYNNGSCVNTATG--YSCRCPFGMSGARCEL 1644 HSP 3 Score: 49.6766 bits (117), Expect = 2.196e-6 Identity = 32/104 (30.77%), Postives = 44/104 (42.31%), Query Frame = 3
Query: 519 ENFVKVTVEHECENGYYPAKQCNKFCFPSENEYTCD---GFGNKICKEGLYFDADENKCLPNNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFCEFANPCF 821
E V +E C+NG C ++ + CD GF KIC + +NC +S CYNNG CVN + + C+C SG CE + F
Sbjct: 1567 ETDVDECLEGPCQNG--------GLCHNTQGGFACDCSAGFSGKICDVTV-----------DNCASSP--CYNNGSCVNTATGYSCRCPFGMSGARCELTSYGF 1649 HSP 4 Score: 48.9062 bits (115), Expect = 3.981e-6 Identity = 25/83 (30.12%), Postives = 39/83 (46.99%), Query Frame = 3
Query: 765 CKCMESYSGKFCEF-ANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCDLKVVQTCK--CPENMRCNYSESGVLFSCTS 1004
C C Y+G +CE + C PC++ G C P G A C C GF+G C+ V + + C C+ ++ G C++
Sbjct: 1517 CTCTAGYAGTWCEADMDECLSTPCRHGGSCQNLPGGFA--CRCLPGFSGTACETDVDECLEGPCQNGGLCHNTQGGFACDCSA 1597
BLAST of Jagged 2-1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004042.1 (pep scaffold:Pmarinus_7.0:GL479143:9150:31231:-1 gene:ENSPMAG00000003698.1 transcript:ENSPMAT00000004042.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 67.3958 bits (163), Expect = 7.765e-12 Identity = 40/118 (33.90%), Postives = 56/118 (47.46%), Query Frame = 3
Query: 654 GLYFDADENKCLPNNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFCEF-ANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCDLKV--VQTCKCPENMRCNYSESGVLFSC 998
G + +AD ++CL S C + G C N F C+C+ +SG CE + C PCQN G C G A C+C GF+G CD+ V + C N C + +G +SC
Sbjct: 1525 GTWCEADMDECL-------STPCRHGGSCQNLPGGFACRCLPGFSGTACETDVDECLEGPCQNGGLCHNTQGGFA--CDCSAGFSGKICDVTVDNCASSPCYNNGSCVNTATG--YSC 1631 HSP 2 Score: 57.7658 bits (138), Expect = 9.050e-9 Identity = 32/100 (32.00%), Postives = 42/100 (42.00%), Query Frame = 3
Query: 627 GFGNKICKEGLYFDADENKCLPNNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFCEFA-NPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCDL 923
GF C + D ++CL C N G C N F C C +SGK C+ + C +PC N G C G Y C C G +G +C+L
Sbjct: 1560 GFSGTAC------ETDVDECLEG-------PCQNGGLCHNTQGGFACDCSAGFSGKICDVTVDNCASSPCYNNGSCVNTATG--YSCRCPFGMSGARCEL 1644 HSP 3 Score: 49.6766 bits (117), Expect = 2.392e-6 Identity = 32/104 (30.77%), Postives = 44/104 (42.31%), Query Frame = 3
Query: 519 ENFVKVTVEHECENGYYPAKQCNKFCFPSENEYTCD---GFGNKICKEGLYFDADENKCLPNNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFCEFANPCF 821
E V +E C+NG C ++ + CD GF KIC + +NC +S CYNNG CVN + + C+C SG CE + F
Sbjct: 1567 ETDVDECLEGPCQNG--------GLCHNTQGGFACDCSAGFSGKICDVTV-----------DNCASSP--CYNNGSCVNTATGYSCRCPFGMSGARCELTSYGF 1649 HSP 4 Score: 48.9062 bits (115), Expect = 4.263e-6 Identity = 25/83 (30.12%), Postives = 39/83 (46.99%), Query Frame = 3
Query: 765 CKCMESYSGKFCEF-ANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCDLKVVQTCK--CPENMRCNYSESGVLFSCTS 1004
C C Y+G +CE + C PC++ G C P G A C C GF+G C+ V + + C C+ ++ G C++
Sbjct: 1517 CTCTAGYAGTWCEADMDECLSTPCRHGGSCQNLPGGFA--CRCLPGFSGTACETDVDECLEGPCQNGGLCHNTQGGFACDCSA 1597
BLAST of Jagged 2-1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002014.1 (pep scaffold:Pmarinus_7.0:GL482490:2146:12219:-1 gene:ENSPMAG00000001825.1 transcript:ENSPMAT00000002014.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 55.8398 bits (133), Expect = 3.781e-9 Identity = 48/150 (32.00%), Postives = 62/150 (41.33%), Query Frame = 3
Query: 495 FELHSITLENFVKVTVEHECENGYYPAKQCNKFCFPSENEYTCD---GFGNKICKEGLYFDADENKCLPNNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFCEF-ANPCFPNPCQNMGKCFIKPNGNAYF-CNCRTGFAGDKCDLKV 929
F H + V + C+NG C YTCD GF K C+ D DE +S C N G CVN +F C C+ Y+G C+ + C +PCQN G+C NG F C+C G+ G CD V
Sbjct: 1 FRGHRMAPGADVDECSPNPCQNGGR--------CIDGAASYTCDCAQGFTGKRCET----DIDE---------CTSDPCQNGGQCVNGAGSFTCSCLAGYTGTLCDSDIDECTSDPCQNGGQCV---NGAGSFTCSCLAGYTGTLCDSDV 126 HSP 2 Score: 51.6026 bits (122), Expect = 9.639e-8 Identity = 32/93 (34.41%), Postives = 46/93 (49.46%), Query Frame = 3
Query: 654 GLYFDADENKCLPNNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFCEF-ANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCDLKV 929
G D+D ++C +S C N G CVN +F C C+ Y+G C+ N C +PC N G+C + A+ C C GF G +C+ V
Sbjct: 81 GTLCDSDIDEC-------TSDPCQNGGQCVNGAGSFTCSCLAGYTGTLCDSDVNECASSPCLNGGRC--RDGVAAFTCECAPGFTGTRCETDV 164
BLAST of Jagged 2-1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002017.1 (pep scaffold:Pmarinus_7.0:GL482490:2146:11907:-1 gene:ENSPMAG00000001825.1 transcript:ENSPMAT00000002017.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 55.4546 bits (132), Expect = 8.033e-9 Identity = 41/117 (35.04%), Postives = 53/117 (45.30%), Query Frame = 3
Query: 594 CFPSENEYTCD---GFGNKICKEGLYFDADENKCLPNNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFCEF-ANPCFPNPCQNMGKCFIKPNGNAYF-CNCRTGFAGDKCDLKV 929
C YTCD GF K C+ D DE +S C N G CVN +F C C+ Y+G C+ + C +PCQN G+C NG F C+C G+ G CD +
Sbjct: 14 CIDGAASYTCDCAQGFTGKRCET----DIDE---------CTSDPCQNGGQCVNGAGSFTCSCLAGYTGTLCDSDIDECTSDPCQNGGQCV---NGAGSFTCSCLAGYTGTLCDSDI 114 HSP 2 Score: 48.9062 bits (115), Expect = 1.206e-6 Identity = 26/72 (36.11%), Postives = 40/72 (55.56%), Query Frame = 3
Query: 720 CYNNGFCVNKGSTFECKCMESYSGKFCEF-ANPCFPNPCQNMGKCFIKPNGNAYF-CNCRTGFAGDKCDLKV 929
C N G C++ +++ C C + ++GK CE + C +PCQN G+C NG F C+C G+ G CD +
Sbjct: 8 CQNGGRCIDGAASYTCDCAQGFTGKRCETDIDECTSDPCQNGGQCV---NGAGSFTCSCLAGYTGTLCDSDI 76
BLAST of Jagged 2-1 vs. Ensembl Sea Lamprey
Match: JAG1 (jagged canonical Notch ligand 1 [Source:HGNC Symbol;Acc:HGNC:6188]) HSP 1 Score: 57.3806 bits (137), Expect = 8.723e-9 Identity = 30/73 (41.10%), Postives = 41/73 (56.16%), Query Frame = 3
Query: 708 SSIQCYNNGFCVNKGSTFECKCMESYSGKFCEF-ANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCDL 923
+S C N G C + ++ C CM+ ++G CE + C PNPCQN +C PNG+ YFC+C F G C L
Sbjct: 357 ASHPCLNGGQCRDAIDSYYCVCMDGFAGDSCELDVDLCVPNPCQNGARCVNLPNGD-YFCHCSENFEGTNCTL 428 HSP 2 Score: 53.1434 bits (126), Expect = 1.680e-7 Identity = 28/68 (41.18%), Postives = 36/68 (52.94%), Query Frame = 3
Query: 720 CYNNGFCVNKGSTFECKCMESYSGKFCEFAN--PCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKC 917
C N G C + G TF C C + G C A C PNPCQN C I +G++Y C C++G+ G C
Sbjct: 581 CNNGGECFDVGDTFRCSCPTGWEGPTCNIAQSIACMPNPCQNGATCVI--SGDSYKCICQSGWEGANC 646 HSP 3 Score: 52.7582 bits (125), Expect = 2.171e-7 Identity = 28/72 (38.89%), Postives = 42/72 (58.33%), Query Frame = 3
Query: 717 QCYNNGFCVNKGSTFECKCMESYSGKFCEF-ANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCDLKV 929
+C N G C + + + C+C Y+G+ CE N C +PC N G+C + ++Y+C C GFAGD C+L V
Sbjct: 322 KCLNGGTCKDLVNDYSCECKPGYTGRRCETEVNECASHPCLNGGQC--RDAIDSYYCVCMDGFAGDSCELDV 391 HSP 4 Score: 48.1358 bits (113), Expect = 6.959e-6 Identity = 52/202 (25.74%), Postives = 81/202 (40.10%), Query Frame = 3
Query: 426 NGGSTINFSHKTINLKKISSKDTFELHSITLENFVKVT--VEHECENGYYPAKQCNKFCFPSEN---EYTCDGFGNKICKEGLYFDADENKCLPNNCIASSIQCYNNG----------------------FCVNKGST--FECKCMESYSGKFCE-FANPCFPN-PCQNMGKCF-IKPNGNAYFCNCRTGFAGDKCDLKVVQ 935
N GS + I+ D + HS V V + C+ Y+ + C K C P ++ Y CD GNK+C +G + C QC N G CV+ G + +EC+C ++ G C+ N C + PC+N G C +P+ +Y C+C+ G+ G C++ VQ
Sbjct: 4 NTGSGTQLITRVTYSGMINPGDQWHNHSAVGARAVTVDYRLRVMCDEHYF-STNCTKLCKPRDDYFGHYACDSNGNKVCLDGWTGGDCKKAICRQGCSTEHGQCDNPGECNCRCQYGWQGHFCDQCIPYPGCVHGGCSKPWECRCDTNWGGLLCDKDLNYCGNHQPCRNGGSCSNAQPD--SYKCDCQKGYHGVNCEIDYVQ 202
BLAST of Jagged 2-1 vs. Ensembl Nematostella
Match: EDO35413 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SLL0]) HSP 1 Score: 69.3218 bits (168), Expect = 3.628e-12 Identity = 37/116 (31.90%), Postives = 53/116 (45.69%), Query Frame = 3
Query: 627 GFGNKICKEGLYFDADENKCLPNNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFCEF-ANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCDLKV--VQTCKCPENMRC 965
GF C+E + N C PN C N G C + +F+C C+ Y+G+ CE + C NPC++ C P G Y C C+ G+ G CD+ + Q+ C N C
Sbjct: 1399 GFTGSQCEESV------NDCNPN-------PCRNEGTCTDNNGSFKCSCIPGYTGRLCESDIDECLTNPCKHASACDNTPGG--YTCTCKPGYTGQNCDVDINYCQSSPCMYNSTC 1499
BLAST of Jagged 2-1 vs. Ensembl Nematostella
Match: EDO29866 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T2E9]) HSP 1 Score: 63.1586 bits (152), Expect = 6.846e-12 Identity = 41/112 (36.61%), Postives = 53/112 (47.32%), Query Frame = 3
Query: 600 PSENEYTCDGFGNK---ICKEGL--YFDADENKCLPNNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFCEFANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCD 920
P N TC FG +C EG +E KC PN C+ N G C F CKC + Y G C + C PNPC++ G C +G+ Y C+CR G+AG C+
Sbjct: 46 PCGNGATCTMFGATFHCLCPEGFRGLTCLEELKCHPNPCL-------NGGMCFENSGGFTCKCADGYRGINCAEHDHCHPNPCRHGGVC--AGDGDDYVCSCRNGWAGTNCE 148 HSP 2 Score: 50.8322 bits (120), Expect = 1.211e-7 Identity = 36/107 (33.64%), Postives = 46/107 (42.99%), Query Frame = 3
Query: 606 ENEYTCD---GFGNKICKEGLYFDADENKCLPNNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFCEFANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKC 917
E++Y CD G+ + C E + N C +S C N C G+TF C C E + G C C PNPC N G CF N + C C G+ G C
Sbjct: 19 EDDYRCDCIHGYRGRDCDEQI-----------NLCDSSP--CGNGATCTMFGATFHCLCPEGFRGLTCLEELKCHPNPCLNGGMCF--ENSGGFTCKCADGYRGINC 110
BLAST of Jagged 2-1 vs. Ensembl Nematostella
Match: EDO41767 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S3G3]) HSP 1 Score: 67.0106 bits (162), Expect = 2.461e-11 Identity = 44/136 (32.35%), Postives = 56/136 (41.18%), Query Frame = 3
Query: 609 NEYTCD---GFGNKICKEGLYFDADENKCLPNNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFCEFANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCDLKV--VQTCKCPENMRCNYSESGVLFSCT 1001
+++ CD G K C + D C N C+ NG C NKGS FECKC SGK CE C PC N G C + A C C GF G C + V Q+ C + C + +C+
Sbjct: 3972 DDFICDCPKGVSGKTC------EVDSRPCASN-------PCFFNGNCTNKGSDFECKCPNDLSGKRCEHGFHCNRLPCMNGGSC--ETRDGAAVCLCPRGFTGLDCSVDVDECQSNPCLNDGACVNTRGSFRCNCS 4092
BLAST of Jagged 2-1 vs. Ensembl Nematostella
Match: EDO33795 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SR75]) HSP 1 Score: 63.5438 bits (153), Expect = 5.259e-11 Identity = 42/121 (34.71%), Postives = 56/121 (46.28%), Query Frame = 3
Query: 600 PSENEYTC---DGFGNKICKEGLYFDADE----NKCLPNNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFCEFANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCDLKVVQTC 941
P +N +C G G IC+ G + E N C PN C+N CV S+F+C CM ++G C+ C PNPCQN G C P N Y C C+ + G+ C+ K C
Sbjct: 163 PCQNGGSCLEEGGLGRCICQMGYHGQHCESESQNVCHPN-------PCHNGATCVATDSSFDCDCMAGWTGPLCQTRQYCIPNPCQNGGTCV--PQENGYRCTCQANYEGNDCERKSANPC 274 HSP 2 Score: 54.6842 bits (130), Expect = 4.978e-8 Identity = 32/78 (41.03%), Postives = 39/78 (50.00%), Query Frame = 3
Query: 720 CYNNGFCVNKGSTFECKCMESYSGKFCEFANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCD---LKVVQTCK 944
C N G C + G +EC C + G+ CE N C PNPC+N G C + Y C CR GF G C+ L V CK
Sbjct: 15 CRNGGTCYDVGQGYECTCARGFKGENCEEINKCHPNPCRNGGMCTGTTSVTGYQCTCREGFKGFDCEEINLCVPNPCK 92
BLAST of Jagged 2-1 vs. Ensembl Nematostella
Match: EDO33048 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7STC0]) HSP 1 Score: 63.1586 bits (152), Expect = 1.201e-10 Identity = 37/99 (37.37%), Postives = 49/99 (49.49%), Query Frame = 3
Query: 708 SSIQCYNNGFCVNKGSTFECKCMESYSGKFCEFANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCDLKVVQTCKCPENMRCNYSESGVLFSCTS 1004
S C N G CVN+GS++ C C +SG C+ +N CF NPC N G C N+Y C C G+ G +C+ V + C C G +CTS
Sbjct: 280 SPTPCLNGGTCVNQGSSYNCTCPAQFSGVICQDSNECFSNPCMNAGTCVDGV--NSYTCTCAEGWTGSRCESSVCLSNPCQNGGTCRQGNGGYYCNCTS 376 HSP 2 Score: 58.151 bits (139), Expect = 5.060e-9 Identity = 30/71 (42.25%), Postives = 40/71 (56.34%), Query Frame = 3
Query: 708 SSIQCYNNGFCVNKGSTFECKCMESYSGKFCEFANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCD 920
S C N G CVN+GS++ C C +SG C+ +N CF NPC N G C N+Y C C G+ G +C+
Sbjct: 130 SPTPCLNGGTCVNQGSSYNCTCPAQFSGVICQDSNECFSNPCMNAGTCVDGV--NSYTCTCAEGWTGSRCE 198 HSP 3 Score: 48.1358 bits (113), Expect = 8.056e-6 Identity = 29/83 (34.94%), Postives = 44/83 (53.01%), Query Frame = 3
Query: 672 DENKCLPNNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFCEFANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCD 920
D N+C N C+ N G CV+ +++ C C E ++G CE ++ C NPCQN G C + Y+CNC + + G C+
Sbjct: 312 DSNECFSNPCM-------NAGTCVDGVNSYTCTCAEGWTGSRCE-SSVCLSNPCQNGGTC--RQGNGGYYCNCTSNYGGYNCE 384
BLAST of Jagged 2-1 vs. Ensembl Medaka
Match: fat1a (FAT atypical cadherin 1 [Source:NCBI gene;Acc:101157514]) HSP 1 Score: 61.2326 bits (147), Expect = 3.519e-9 Identity = 29/77 (37.66%), Postives = 38/77 (49.35%), Query Frame = 3
Query: 720 CYNNGFCVNKGSTFECKCMESYSGKFCEFANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCDLKVVQTCKCP 950
C G CV + F C+C YSG+ C+ C NPC+N GKC +G C C GF G++C V + K P
Sbjct: 4094 CLYGGTCVPRAGDFYCQCRGQYSGQRCQLGPYCKDNPCKNSGKCIDSLDGPV--CECEAGFQGERCLSDVDECIKSP 4168
BLAST of Jagged 2-1 vs. Ensembl Medaka
Match: fat1a (FAT atypical cadherin 1 [Source:NCBI gene;Acc:101157514]) HSP 1 Score: 61.2326 bits (147), Expect = 3.619e-9 Identity = 29/77 (37.66%), Postives = 38/77 (49.35%), Query Frame = 3
Query: 720 CYNNGFCVNKGSTFECKCMESYSGKFCEFANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCDLKVVQTCKCP 950
C G CV + F C+C YSG+ C+ C NPC+N GKC +G C C GF G++C V + K P
Sbjct: 4071 CLYGGTCVPRAGDFYCQCRGQYSGQRCQLGPYCKDNPCKNSGKCIDSLDGPV--CECEAGFQGERCLSDVDECIKSP 4145
BLAST of Jagged 2-1 vs. Ensembl Medaka
Match: fat1a (FAT atypical cadherin 1 [Source:NCBI gene;Acc:101157514]) HSP 1 Score: 61.2326 bits (147), Expect = 3.650e-9 Identity = 29/77 (37.66%), Postives = 38/77 (49.35%), Query Frame = 3
Query: 720 CYNNGFCVNKGSTFECKCMESYSGKFCEFANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCDLKVVQTCKCP 950
C G CV + F C+C YSG+ C+ C NPC+N GKC +G C C GF G++C V + K P
Sbjct: 4094 CLYGGTCVPRAGDFYCQCRGQYSGQRCQLGPYCKDNPCKNSGKCIDSLDGPV--CECEAGFQGERCLSDVDECIKSP 4168
BLAST of Jagged 2-1 vs. Ensembl Medaka
Match: fat1a (FAT atypical cadherin 1 [Source:NCBI gene;Acc:101157514]) HSP 1 Score: 61.2326 bits (147), Expect = 3.650e-9 Identity = 29/77 (37.66%), Postives = 38/77 (49.35%), Query Frame = 3
Query: 720 CYNNGFCVNKGSTFECKCMESYSGKFCEFANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCDLKVVQTCKCP 950
C G CV + F C+C YSG+ C+ C NPC+N GKC +G C C GF G++C V + K P
Sbjct: 4094 CLYGGTCVPRAGDFYCQCRGQYSGQRCQLGPYCKDNPCKNSGKCIDSLDGPV--CECEAGFQGERCLSDVDECIKSP 4168
BLAST of Jagged 2-1 vs. Ensembl Medaka
Match: fat1a (FAT atypical cadherin 1 [Source:NCBI gene;Acc:101157514]) HSP 1 Score: 61.2326 bits (147), Expect = 3.650e-9 Identity = 29/77 (37.66%), Postives = 38/77 (49.35%), Query Frame = 3
Query: 720 CYNNGFCVNKGSTFECKCMESYSGKFCEFANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCDLKVVQTCKCP 950
C G CV + F C+C YSG+ C+ C NPC+N GKC +G C C GF G++C V + K P
Sbjct: 4094 CLYGGTCVPRAGDFYCQCRGQYSGQRCQLGPYCKDNPCKNSGKCIDSLDGPV--CECEAGFQGERCLSDVDECIKSP 4168
BLAST of Jagged 2-1 vs. Planmine SMEST
Match: SMESG000025147.1 (SMESG000025147.1) HSP 1 Score: 1013.06 bits (2618), Expect = 0.000e+0 Identity = 508/510 (99.61%), Postives = 509/510 (99.80%), Query Frame = 3
Query: 99 MLTLRVSLAHILIALLFFGFSYSLHITQANFNSQQSPAKVNLRFLISKFSQLLTSEPVKFSLCIDKNHEKCFWTTNKNVELHEELFQEVQFEFYINNMDTNLSISIKLENGGSTINFSHKTINLKKISSKDTFELHSITLENFVKVTVEHECENGYYPAKQCNKFCFPSENEYTCDGFGNKICKEGLYFDADENKCLPNNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFCEFANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCDLKVVQTCKCPENMRCNYSESGVLFSCTSINEDNRENPENPLYEKPIKKSENKQNQNWNNVSSTTTIVAAIGCFMVLISIGVSVYVCQRTRNYSSLIKSRTSEGTQSNFLNQYPPKFESTFKRSFSLEDNSAYLPVNSTVLTNSPQLITLGSSNGFSVHSNSYQDNPAISFVSYPSTYNEICKQDPRSGYMIMTRNCGENSNTDTNTLSSGSIXXXXXXXXXNIDNESPILLTQNSE 1628
MLTLRVSLAHILIALLFFGFSYSLHITQANFNSQQSPAKVNLRFLISKFSQLLTSEPVKFSLCIDKNHEKCFWTTNKNVELHEELFQEVQFEFYINNMDTNLSISIKLENGGSTINFSHKTINLKKISSKDTFELHSITLENFVKVTVEHECENGYYPAKQCNKFCFPSENEYTCDGFGNKICKEGLYFDADENKCLPNNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFCEFANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCD KVVQTCKCPENMRCNYSESGVLFSCTSIN+DNRENPENPLYEKPIKKSENKQNQNWNNVSSTTTIVAAIGCFMVLISIGVSVYVCQRTRNYSSLIKSRTSEGTQSNFLNQYPPKFESTFKRSFSLEDNSAYLPVNSTVLTNSPQLITLGSSNGFSVHSNSYQDNPAISFVSYPSTYNEICKQDPRSGYMIMTRNCGENSNTDTNTLSSGSIPPPALPPRPNIDNESPILLTQNSE
Sbjct: 1 MLTLRVSLAHILIALLFFGFSYSLHITQANFNSQQSPAKVNLRFLISKFSQLLTSEPVKFSLCIDKNHEKCFWTTNKNVELHEELFQEVQFEFYINNMDTNLSISIKLENGGSTINFSHKTINLKKISSKDTFELHSITLENFVKVTVEHECENGYYPAKQCNKFCFPSENEYTCDGFGNKICKEGLYFDADENKCLPNNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFCEFANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCDFKVVQTCKCPENMRCNYSESGVLFSCTSINDDNRENPENPLYEKPIKKSENKQNQNWNNVSSTTTIVAAIGCFMVLISIGVSVYVCQRTRNYSSLIKSRTSEGTQSNFLNQYPPKFESTFKRSFSLEDNSAYLPVNSTVLTNSPQLITLGSSNGFSVHSNSYQDNPAISFVSYPSTYNEICKQDPRSGYMIMTRNCGENSNTDTNTLSSGSIPPPALPPRPNIDNESPILLTQNSE 510
BLAST of Jagged 2-1 vs. Planmine SMEST
Match: SMESG000005484.1 (SMESG000005484.1) HSP 1 Score: 111.694 bits (278), Expect = 1.133e-25 Identity = 112/421 (26.60%), Postives = 182/421 (43.23%), Query Frame = 3
Query: 198 QQSPAKVNLRFLISKFSQLLTSEPVKFSL--CIDKNH---EKCFW---TTNKNVELHEELFQEVQFEFYINNMDTNLSISIKLENGGSTINFSHKTINLKKISSKDTFELHSITLENFVKVTVEH--ECENGYYPAKQCNKFCFPSENEYTCDGFGNKICKEGLYFDADENKCLPNNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFCEFANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCDLKVVQTC---KCPENMRCNY------------SESGV---LFSCTSINEDNRENP---------ENPLYEK-PIKKSENK--QNQNWNNVSSTTTIVAA-----IGCFMVLISIGVSVYVCQRTRNYS--SLIKSRTSEGTQSNFLNQYPPKFESTFKRSFSLEDNSAYL 1319
+++P + L+ + + + K+ L C+ E+C W T N N H+ + F ++N+ + L + I KT N K I ++ + I ++F ++V+ +C+ G++P +C CF + Y CD G KIC G FD NKC +NC + +I C+NNG CV+ +C C++ +SG CE +PC C+N GKC N + C C+ + G C+ K ++C C +N C S+S + + SI P + P+ E P+ K N+ Q+ + N +TT IV IGCF V + Y ++++ YS S + S S + + E F+R SL+DNS YL
Sbjct: 26 KRAPGTLTLKIQTPAYVEDCVEKYCKYVLKSCVGSGRSENERCLWSPLTVNSNY-FHKMPKYLAEISFEVDNVKDPFYFNANLSYFQNEILV--KTENFKNIIIQNLYGATQIHSQDFATLSVDIVIKCKPGFFPKNRCLVSCFEEASVYKCDENGRKICLSGYVFDPLTNKCNLDNCNSENIICFNNGTCVSGAHNPKCFCVDGFSGPSCEIWDPCAKPRCKNGGKCIKSELKNDFICFCKNNYYGKNCE-KTGKSCNDITCEKNQFCEIVNNQPKCSVKKNSKSFIQKTFVTPPSIKSTTITKPKLVSLNVETKKPIVESIPVSKGTNRLLQSHSLLNEYTTTAIVIVLVVFMIGCFGVTFWVLKIKYFQKKSKTYSNFSTLPVMPSIYNASTYRSS-----EENFRRWHSLDDNSFYL 437
BLAST of Jagged 2-1 vs. Planmine SMEST
Match: SMESG000059836.1 (SMESG000059836.1) HSP 1 Score: 78.9518 bits (193), Expect = 2.203e-15 Identity = 89/380 (23.42%), Postives = 150/380 (39.47%), Query Frame = 3
Query: 144 LFFGFSYSLHITQANFNSQQSPAKVNLRFLISKFSQLLTSEPVKFSLCIDKNH-EKCFWTTNKNVELHEELFQEVQFEFYINNM----DTNLSISIKLENGGSTINFSHKTINLKKISSKDTFELHS---ITLENFVK------VTVEHECENGYYPAKQCNKFCFPSENEYTCDGFGNKICKEGLYFDADENKCLPNNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFCEFANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCDLKVVQTCKCPENMRCNYSESGVLFSCTSINEDNRENPENPLYEKPIKKSENKQNQNWNNVSSTTTIVAAIGCFMV-LISIGVSVYVCQRTR--NYSSLIKSRTSEGT 1232
++F F +L I+ F Q+P + + L + V ++ + + ++L + E+ +F + N+ D N + I ++NG T + + I+ K S+K +F L++ +T + K V +C+ +YP C+ C ++ CD GNKIC++G YF+ C + C S C N+G CVN+ EC C YSGK+C+ L + Q CP C+ V T I+ D +E N Q N+ V S TI++ G +V +I+I ++++ C+R R Y S+ S S T
Sbjct: 4 IYFVFV-ALGISSVGFARFQAPGTITMNIKYHPDIYLYGDDNVTLDSTVNTTKMRRELYKKADRMKLLSDGALELTIKFDVYNISEHIDYNGLMKI-MQNGRKTETYEFRLISFK-FSTKKSFLLNNMRYVTATAYSKEYKELEVMTSVKCKQNFYPEFNCSVLCVKTQTIEKCDSNGNKICRKGFYFNDYTQTCDTDWCTQSKPICVNDGHCVNRRKESECVCGPLYSGKYCQIP-------------------------------------LNLCQQHNCPNKTYCSVQIGKV----TCISLDQKELVSN-------------QGNNYFKVMSAYTILSMFGFVIVFIITILLTIWACKRQRFERYRSMDASIHSSHT 326
BLAST of Jagged 2-1 vs. Planmine SMEST
Match: SMESG000063217.1 (SMESG000063217.1) HSP 1 Score: 68.5514 bits (166), Expect = 1.499e-11 Identity = 46/116 (39.66%), Postives = 59/116 (50.86%), Query Frame = 3
Query: 594 CFPSENEYTCDGFGNKICKEGLYFDADENKCLPNNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFCE-FANPCFPNPCQNMGKCF---IKPNGNAYFCNCRTGFAGDKCDLKV 929
C N+Y C IC+ G F + N+C SS C +G CV+K + FECKC E+Y G CE PC NPC N G C + N Y CNCR GF G +C++K+
Sbjct: 750 CIDHINDYQC------ICQSG--FSGKNCEINDNDCTESS--CLGHGQCVDKVNGFECKCNENYIGTNCEHLKRPCDSNPCLNKGSCINRKVNQNTPGYLCNCRRGFTGPRCEIKM 855
BLAST of Jagged 2-1 vs. Planmine SMEST
Match: SMESG000066558.1 (SMESG000066558.1) HSP 1 Score: 58.151 bits (139), Expect = 1.999e-8 Identity = 35/87 (40.23%), Postives = 44/87 (50.57%), Query Frame = 3
Query: 693 NNCIASSIQCYNNGFCVNK-GSTFECKCMESYSGKFCEFANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCDLKVVQTCKCP 950
N+CI + C N G C++K S F C C + G C+F NPC C+N G C NG + C CR GF G+ C VQ CP
Sbjct: 54 NDCIQNP--CKNGGTCIDKKNSQFTCNCTSQFIGNLCQFENPCLNVNCENGGTCESLENG-MFQCKCRYGFIGEFC---AVQNIACP 134 HSP 2 Score: 51.9878 bits (123), Expect = 1.397e-6 Identity = 34/92 (36.96%), Postives = 44/92 (47.83%), Query Frame = 3
Query: 675 ENKCLPNNCIASSIQCYNNGFCVN-KGSTFECKCMESYSGKFCEFAN---PCFPNP----CQNMGKCFIKPNGNAYFCNCRTGFAGDKCDLK 926
EN CL ++ C N G C + + F+CKC + G+FC N P P C N G+C I PN FC C G+ GD+CD K
Sbjct: 91 ENPCL-------NVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPN-MTLFCKCDPGYTGDRCDKK 174 The following BLAST results are available for this feature:
BLAST of Jagged 2-1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Jagged 2-1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Jagged 2-1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Jagged 2-1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Jagged 2-1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Jagged 2-1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Jagged 2-1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Jagged 2-1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Jagged 2-1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Jagged 2-1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Jagged 2-1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of Jagged 2-1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Jagged 2-1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Jagged 2-1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30017862 ID=SMED30017862|Name=Jagged 2-1|organism=Schmidtea mediterranea sexual|type=transcript|length=1955bpback to top protein sequence of SMED30017862-orf-1 >SMED30017862-orf-1 ID=SMED30017862-orf-1|Name=SMED30017862-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=511bp MLTLRVSLAHILIALLFFGFSYSLHITQANFNSQQSPAKVNLRFLISKFSback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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