Sorting nexin-2

Overview


Name	Sorting nexin-2
Smed ID	SMED30017841
Length (bp)	1629

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of Sorting nexin-2 (SMED30017841) t-SNE clustered cells

Violin plots show distribution of expression levels for Sorting nexin-2 (SMED30017841) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Sorting nexin-2 (SMED30017841) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Sorting nexin-2 (SMED30017841) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30017841

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 12

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
intestinal phagocyte	SMED30017841	SMESG000064358.1	Contig4400	GPL15192	PMID:23079596 Forsthoefel et al., 2012
intestinal phagocyte	SMED30017841	SMESG000016192.1	PL030008B20E06	ncbi_smed_ests	PMID:23079596 Forsthoefel et al., 2012
intestinal phagocyte	SMED30017841	SMESG000016192.1	Contig4400	GPL15192	PMID:23079596 Forsthoefel et al., 2012
protonephridia	SMED30017841	SMESG000016192.1	dd_Smed_v4_835_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
gut	SMED30017841	SMESG000016192.1	dd_Smed_v4_835_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
epidermis	SMED30017841	SMESG000016192.1	dd_Smed_v4_835_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30017841	SMESG000016192.1	dd_Smed_v4_835_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
neoblast	SMED30017841	SMESG000016192.1	dd_Smed_v4_835_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parenchymal cell	SMED30017841	SMESG000016192.1	dd_Smed_v4_835_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30017841	SMESG000016192.1	Contig49791	newmark_ests	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30017841	SMESG000016192.1	Contig49791	uc_Smed_v2	PMID:29674431 Fincher et al., 2018
epidermis	SMED30017841	SMESG000016192.1	dd_Smed_v4_835_0_1	dd_Smed_v4	PMID:28292427 Wurtzel et al., 2017

Note: Hover over icons to view figure legend

Homology

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BLAST of Sorting nexin-2 vs. Ensembl Human
Match: SNX2 (sorting nexin 2 [Source:HGNC Symbol;Acc:HGNC:11173])

HSP 1 Score: 334.339 bits (856), Expect = 9.980e-110
Identity = 178/383 (46.48%), Postives = 259/383 (67.62%), Query Frame = 3

Query:  267 IEISVSYPEKLGSGMAAYFIYKINTKTNRPSFLHQEITVRRRFSDFLGLHERLKLKYLFAGCIIPPAPEKNAFGNTKLKLSKEDQTNSEFXXXXXXXXXXYLQRIARHPLLVIDADFREFLEDDKELPKAVNTQVLSGANMKKLFKNVGDAVGKITTKMDDCDQKDILWFDDKQVEMDNLDRHLSQIHCSFEHLISQRKELASQIKVFAQNCSQLSHVEEHNGLARALAQLXXXXXXXXXXXXRQAEVEFYTLLELLKDYLGMIGAVKEVLNERIRQYRVWQEAESNLNKKREQKARCEISGKVDKIPAFDLEIKECLNKVDRTREDFEKISKTIKTELEAFDTTKVIDFKEGIIKVLEAMISSQEEIIHQWEKYIPDTAGIS 1415
            IEI VS PEK+G GM AY  Y++ TKT+   F   E +V+RRFSDFLGLH +L  KYL  G I+PPAPEK+  G TK+K+ KED +++EF+E+RRAALERYLQR  +HP L+ D D R+FLE   ELP+AVNTQ LSGA + ++     DAV K+T KM++ D     WF++KQ + +NLD+ L ++H S E L+  RKEL++    FA++ + L + E+H  L+RAL+QL+  +E+I  + + QA  +FY   ELL DY+ +I AVK V + R++ ++ W++A+  L KKRE +A+  ++ K DKI     EI+E   KV +   DFE+ISKTI+ E+  F+  +V DFK  IIK LE+++ +Q+++I  WE ++P+   I+
Sbjct:   25 IEIGVSDPEKVGDGMNAYMAYRVTTKTSLSMFSKSEFSVKRRFSDFLGLHSKLASKYLHVGYIVPPAPEKSIVGMTKVKVGKEDSSSTEFVEKRRAALERYLQRTVKHPTLLQDPDLRQFLESS-ELPRAVNTQALSGAGILRMVNKAADAVNKMTIKMNESDA----WFEEKQQQFENLDQQLRKLHVSVEALVCHRKELSANTAAFAKSAAMLGNSEDHTALSRALSQLAEVEEKIDQLHQEQAFADFYMFSELLSDYIRLIAAVKGVFDHRMKCWQKWEDAQITLLKKREAEAKMMVANKPDKIQQAKNEIREWEAKVQQGERDFEQISKTIRKEVGRFEKERVKDFKTVIIKYLESLVQTQQQLIKYWEAFLPEAKAIA 402

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BLAST of Sorting nexin-2 vs. Ensembl Human
Match: SNX2 (sorting nexin 2 [Source:HGNC Symbol;Acc:HGNC:11173])

HSP 1 Score: 337.806 bits (865), Expect = 2.014e-109
Identity = 197/465 (42.37%), Postives = 286/465 (61.51%), Query Frame = 3

Query:   87 DDDDIFEEAMENTDEFGVQTEIRLD----EPTITRNASPPRTSVTEIS----------------NDRVPNQRKISKTGKF--IEISVSYPEKLGSGMAAYFIYKINTKTNRPSFLHQEITVRRRFSDFLGLHERLKLKYLFAGCIIPPAPEKNAFGNTKLKLSKEDQTNSEFXXXXXXXXXXYLQRIARHPLLVIDADFREFLEDDKELPKAVNTQVLSGANMKKLFKNVGDAVGKITTKMDDCDQKDILWFDDKQVEMDNLDRHLSQIHCSFEHLISQRKELASQIKVFAQNCSQLSHVEEHNGLARALAQLXXXXXXXXXXXXRQAEVEFYTLLELLKDYLGMIGAVKEVLNERIRQYRVWQEAESNLNKKREQKARCEISGKVDKIPAFDLEIKECLNKVDRTREDFEKISKTIKTELEAFDTTKVIDFKEGIIKVLEAMISSQEEIIHQWEKYIPDTAGIS 1415
            D +D+F EA E         E+ LD    EP ++   SP  T VT  +                 DR   + +    G    IEI VS PEK+G GM AY  Y++ TKT+   F   E +V+RRFSDFLGLH +L  KYL  G I+PPAPEK+  G TK+K+ KED +++EF+E+RRAALERYLQR  +HP L+ D D R+FLE   ELP+AVNTQ LSGA + ++     DAV K+T KM++ D     WF++KQ + +NLD+ L ++H S E L+  RKEL++    FA++ + L + E+H  L+RAL+QL+  +E+I  + + QA  +FY   ELL DY+ +I AVK V + R++ ++ W++A+  L KKRE +A+  ++ K DKI     EI+E   KV +   DFE+ISKTI+ E+  F+  +V DFK  IIK LE+++ +Q+++I  WE ++P+   I+
Sbjct:   69 DREDLFAEATE---------EVSLDSPEREPILSSEPSPAVTPVTPTTLIAPRIESKSMSAPVIFDRSREEIEEEANGDIFDIEIGVSDPEKVGDGMNAYMAYRVTTKTSLSMFSKSEFSVKRRFSDFLGLHSKLASKYLHVGYIVPPAPEKSIVGMTKVKVGKEDSSSTEFVEKRRAALERYLQRTVKHPTLLQDPDLRQFLESS-ELPRAVNTQALSGAGILRMVNKAADAVNKMTIKMNESDA----WFEEKQQQFENLDQQLRKLHVSVEALVCHRKELSANTAAFAKSAAMLGNSEDHTALSRALSQLAEVEEKIDQLHQEQAFADFYMFSELLSDYIRLIAAVKGVFDHRMKCWQKWEDAQITLLKKREAEAKMMVANKPDKIQQAKNEIREWEAKVQQGERDFEQISKTIRKEVGRFEKERVKDFKTVIIKYLESLVQTQQQLIKYWEAFLPEAKAIA 519

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BLAST of Sorting nexin-2 vs. Ensembl Human
Match: SNX1 (sorting nexin 1 [Source:HGNC Symbol;Acc:HGNC:11172])

HSP 1 Score: 296.204 bits (757), Expect = 2.003e-93
Identity = 162/383 (42.30%), Postives = 251/383 (65.54%), Query Frame = 3

Query:  267 IEISVSYPEKLGSGMAAYFIYKINTKTNRPSFLHQEITVRRRFSDFLGLHERLKLKYLFAGCIIPPAPEKNAFGNTKLKLSKEDQTNSEFXXXXXXXXXXYLQRIARHPLLVIDADFREFLEDDKELPKAVNTQVLSGANMKKLFKNVGDAVGKITTKMDDCDQKDILWFDDKQVEMDNLDRHLSQIHCSFEHLISQRKELASQIKVFAQNCSQLSHVEEHNGLARALAQLXXXXXXXXXXXXRQAEVEFYTLLELLKDYLGMIGAVKEVLNERIRQYRVWQEAESNLNKKREQKARCEISGKVDKIPAFDLEIKECLNKVDRTREDFEKISKTIKTELEAFDTTKVIDFKEGIIKVLEAMISSQEEIIHQWEKYIPDTAGIS 1415
            + + ++ PEK+G GM AY  YK+ T+T+ P F  ++  V+RRFSDFLGL+E+L  K+   G I+PP PEK+  G TK+K+ KED +++EFLE+RRAALERYLQRI  HP ++ D D REFLE + ELP+AV TQ LSGA + K+F    DAV K+T KM++ D    +WF++K  E++  ++ L ++H   E L++ RKELA     FA++ + L   E++  L+RAL+QL+  +E+I  + + QA  +F+ L ELL DY+ ++  V+   ++R++ ++ WQ+A++ L KKRE +AR   + K DK+     EI E  ++V +   DFE+IS  ++ E+  F+  K  DFK  +IK LE ++ SQ+++   WE ++P+   IS
Sbjct:  145 LTVGITDPEKIGDGMNAYVAYKVTTQTSLPLFRSKQFAVKRRFSDFLGLYEKLSEKHSQNGFIVPPPPEKSLIGMTKVKVGKEDSSSAEFLEKRRAALERYLQRIVNHPTMLQDPDVREFLEKE-ELPRAVGTQTLSGAGLLKMFNKATDAVSKMTIKMNESD----IWFEEKLQEVECEEQRLRKLHAVVETLVNHRKELALNTAQFAKSLAMLGSSEDNTALSRALSQLAEVEEKIEQLHQEQANNDFFLLAELLSDYIRLLAIVRAAFDQRMKTWQRWQDAQATLQKKREAEARLLWANKPDKLQQAKDEILEWESRVTQYERDFERISTVVRKEVIRFEKEKSKDFKNHVIKYLETLLYSQQQLAKYWEAFLPEAKAIS 522

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BLAST of Sorting nexin-2 vs. Ensembl Human
Match: SNX1 (sorting nexin 1 [Source:HGNC Symbol;Acc:HGNC:11172])

HSP 1 Score: 286.574 bits (732), Expect = 1.668e-90
Identity = 159/372 (42.74%), Postives = 243/372 (65.32%), Query Frame = 3

Query:  300 GSGMAAYFIYKINTKTNRPSFLHQEITVRRRFSDFLGLHERLKLKYLFAGCIIPPAPEKNAFGNTKLKLSKEDQTNSEFXXXXXXXXXXYLQRIARHPLLVIDADFREFLEDDKELPKAVNTQVLSGANMKKLFKNVGDAVGKITTKMDDCDQKDILWFDDKQVEMDNLDRHLSQIHCSFEHLISQRKELASQIKVFAQNCSQLSHVEEHNGLARALAQLXXXXXXXXXXXXRQAEVEFYTLLELLKDYLGMIGAVKEVLNERIRQYRVWQEAESNLNKKREQKARCEISGKVDKIPAFDLEIKECLNKVDRTREDFEKISKTIKTELEAFDTTKVIDFKEGIIKVLEAMISSQEEIIHQWEKYIPDTAGIS 1415
            G GM AY  YK+ T+T+ P F  ++  V+RRFSDFLGL+E+L  K+   G I+PP PEK+  G TK+K+ KED +++EFLE+RRAALERYLQRI  HP ++ D D REFLE + ELP+AV TQ LSGA + K+F    DAV K+T KM++ D    +WF++K  E++  ++ L ++H   E L++ RKELA     FA++ + L   E++  L+RAL+QL+  +E+I  + + QA  +F+ L ELL DY+ ++  V+   ++R++ ++ WQ+A++ L KKRE +AR   + K DK+     EI E  ++V +   DFE+IS  ++ E+  F+  K  DFK  +IK LE ++ SQ+++   WE ++P+   IS
Sbjct:   91 GDGMNAYVAYKVTTQTSLPLFRSKQFAVKRRFSDFLGLYEKLSEKHSQNGFIVPPPPEKSLIGMTKVKVGKEDSSSAEFLEKRRAALERYLQRIVNHPTMLQDPDVREFLEKE-ELPRAVGTQTLSGAGLLKMFNKATDAVSKMTIKMNESD----IWFEEKLQEVECEEQRLRKLHAVVETLVNHRKELALNTAQFAKSLAMLGSSEDNTALSRALSQLAEVEEKIEQLHQEQANNDFFLLAELLSDYIRLLAIVRAAFDQRMKTWQRWQDAQATLQKKREAEARLLWANKPDKLQQAKDEILEWESRVTQYERDFERISTVVRKEVIRFEKEKSKDFKNHVIKYLETLLYSQQQLAKYWEAFLPEAKAIS 457

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BLAST of Sorting nexin-2 vs. Ensembl Human
Match: SNX1 (sorting nexin 1 [Source:HGNC Symbol;Acc:HGNC:11172])

HSP 1 Score: 281.567 bits (719), Expect = 2.089e-87
Identity = 158/371 (42.59%), Postives = 243/371 (65.50%), Query Frame = 3

Query:  267 IEISVSYPEKLGSGMAAYFIYKINTKTNRPSFLHQEITVRRRFSDFLGLHERLKLKYLFAGCIIPPAPEKNAFGNTKLKLSKEDQTNSEFXXXXXXXXXXYLQRIARHPLLVIDADFREFLEDDKELPKAVNTQVLSGANMKKLFKNVGDAVGKITTKMDDCDQKDILWFDDKQVEMDNLDRHLSQIHCSFEHLISQRKELASQIKVFAQNCSQLSHVEEHNGLARALAQLXXXXXXXXXXXXRQAEVEFYTLLELLKDYLGMIGAVKEVLNERIRQYRVWQEAESNLNKKREQKARCEISGKVDKIPAFDLEIKECLNKVDRTREDFEKISKTIKTELEAFDTTKVIDFKEGIIKVLEAMISSQEEIIHQ 1379
            + + ++ PEK+G GM AY  YK+ T+T+ P F  ++  V+RRFSDFLGL+E+L  K+   G I+PP PEK+  G TK+K+ KED +++EFLE+RRAALERYLQRI  HP ++ D D REFLE + ELP+AV TQ LSGA + K+F    DAV K+T KM++ D    +WF++K  E++  ++ L ++H   E L++ RKELA     FA++ + L   E++  L+RAL+QL+  +E+I  + + QA  +F+ L ELL DY+ ++  V+   ++R++ ++ WQ+A++ L KKRE +AR   + K DK+     EI E  ++V +   DFE+IS  ++ E+  F+  K  DFK  +IK LE ++ SQ++   Q
Sbjct:  145 LTVGITDPEKIGDGMNAYVAYKVTTQTSLPLFRSKQFAVKRRFSDFLGLYEKLSEKHSQNGFIVPPPPEKSLIGMTKVKVGKEDSSSAEFLEKRRAALERYLQRIVNHPTMLQDPDVREFLEKE-ELPRAVGTQTLSGAGLLKMFNKATDAVSKMTIKMNESD----IWFEEKLQEVECEEQRLRKLHAVVETLVNHRKELALNTAQFAKSLAMLGSSEDNTALSRALSQLAEVEEKIEQLHQEQANNDFFLLAELLSDYIRLLAIVRAAFDQRMKTWQRWQDAQATLQKKREAEARLLWANKPDKLQQAKDEILEWESRVTQYERDFERISTVVRKEVIRFEKEKSKDFKNHVIKYLETLLYSQQQAGEQ 510

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BLAST of Sorting nexin-2 vs. Ensembl Celegans
Match: snx-1 (Sorting NeXin [Source:UniProtKB/TrEMBL;Acc:Q9GYJ9])

HSP 1 Score: 213.386 bits (542), Expect = 8.006e-63
Identity = 132/377 (35.01%), Postives = 221/377 (58.62%), Query Frame = 3

Query:  291 EKLGSGMAAYFIYKINTK-TNRPSFLHQEITVRRRFSDFLGLHERLKLKYLFAGCIIPPAPEKNAFGNTKLKLSKEDQTNSEFXXXXXXXXXXYLQRIARHPLLVIDADFREFLEDDKELPKAVNTQVLSGANMKKLFKNVGDAVGKITTKMDDCDQKDILWFDDKQVEMDNLDRHLSQIHCSFEHLISQRKELASQIKVFAQNCSQLSHVEEHNGLARALAQLXXXXXXXXXXXXRQAEVEFYTLLELLKDYLGMIGAVKEVLNERIRQYRVWQEAESNLNKKREQKARCEIS--GKVDKIPAFDLEIKECLNKVDRTREDFEKISKTIKTELEAFDTTKVIDFKEGIIKVLEAMISSQEEIIHQWEKYIPDTAGI 1412
            EK G GM AY +YK+ T+ +    +  Q     RRFSDFLGLH ++  KYL  G +IP  PEK+    TK K + +   + E   +R   LERY+ R+ +HP +  D D R+FL  + +LPKAV T  LS   +KK+FKN      K+   M++ D+    WF+  Q ++D LD  L +++   E L++ R+++A+  +   +  S L+  EE   L+RAL+ L+   E +SA+  +QAEV+     E + +Y+ +I A+K+V  ER+R ++ WQ+A+  L +KR+QK + ++S  G+ ++      EI++ + K+D+  + F ++SK I+ E+  FD  +  D K+ +++ +E+MI +  E++H WEK+ P+   I
Sbjct:   98 EKRGDGMNAYIVYKLETEVSGVVGYTKQHYETWRRFSDFLGLHGKIVEKYLAKGIVIPQPPEKSISALTKTKTNSDPAMSREVGIQRARQLERYICRLIQHPRMRNDCDVRDFLTIESDLPKAVQTAALSSFGVKKIFKNFQVVFSKMAFHMEEGDR----WFEQVQSQVDELDEALRKLYTVTETLVASRRDMATSGEQLGKALSMLAACEESTSLSRALSSLTDVTENVSAVYGKQAEVDNSKFSESIYEYIMLISALKDVFGERVRAWQQWQDAQQTLARKRDQKTKIDLSAGGRNERSDQLKGEIEDTVQKMDQLEQHFIELSKAIREEVARFDADRKQDMKKMLVEYMESMIHTHTELLHLWEKFEPEANNI 470

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Query:  291 EKLGSGMAAYFIYKINTK-TNRPSFLHQEITVRRRFSDFLGLHERLKLKYLFAGCIIPPAPEKNAFGNTKLKLSKEDQTNSEFXXXXXXXXXXYLQRIARHPLLVIDADFREFLEDDKELPKAVNTQVLSGANMKKLFKNVGDAVGKITTKMDDCDQKDILWFDDKQVEMDNLDRHLSQIHCSFEHLISQRKELASQIKVFAQNCSQLSHVEEHNGLARALAQLXXXXXXXXXXXXRQAEVEFYTLLELLKDYLGMIGAVKEVLNERIRQYRVWQEAESNLNKKREQKARCEIS--GKVDKIPAFDLEIKECLNKVDRTREDFEKISKTIKTELEAFDTTKVIDFKEGIIKVLEAMISSQEEIIHQWEKYIPDTAGI 1412
            EK G GM AY +YK+ T+ +    +  Q     RRFSDFLGLH ++  KYL  G +IP  PEK+    TK K + +   + E   +R   LERY+ R+ +HP +  D D R+FL  + +LPKAV T  LS   +KK+FKN      K+   M++ D+    WF+  Q ++D LD  L +++   E L++ R+++A+  +   +  S L+  EE   L+RAL+ L+   E +SA+  +QAEV+     E + +Y+ +I A+K+V  ER+R ++ WQ+A+  L +KR+QK + ++S  G+ ++      EI++ + K+D+  + F ++SK I+ E+  FD  +  D K+ +++ +E+MI +  E++H WEK+ P+   I
Sbjct:   98 EKRGDGMNAYIVYKLETEVSGVVGYTKQHYETWRRFSDFLGLHGKIVEKYLAKGIVIPQPPEKSISALTKTKTNSDPAMSREVGIQRARQLERYICRLIQHPRMRNDCDVRDFLTIESDLPKAVQTAALSSFGVKKIFKNFQVVFSKMAFHMEEGDR----WFEQVQSQVDELDEALRKLYTVTETLVASRRDMATSGEQLGKALSMLAACEESTSLSRALSSLTDVTENVSAVYGKQAEVDNSKFSESIYEYIMLISALKDVFGERVRAWQQWQDAQQTLARKRDQKTKIDLSAGGRNERSDQLKGEIEDTVQKMDQLEQHFIELSKAIREEVARFDADRKQDMKKMLVEYMESMIHTHTELLHLWEKFEPEANNI 470

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BLAST of Sorting nexin-2 vs. Ensembl Celegans
Match: snx-6 (Sorting NeXin [Source:UniProtKB/TrEMBL;Acc:D9PTP8])

HSP 1 Score: 85.8853 bits (211), Expect = 1.227e-17
Identity = 97/362 (26.80%), Postives = 159/362 (43.92%), Query Frame = 3

Query:  327 YKINTKTNRPSFLHQEITVRRRFSDFLGLHERLKLKYLFAGCIIPPAPEKNAFGNTKLKLSK-----EDQTNSEFXXXXXXXXXXY--------------LQRIARHPLLVIDADFREFLEDDKELPKAVNTQVLSGANMKKLFKNVGDAVGKITTKMDDCDQKDI-LWFDDKQVEMDNLDRHLSQIHCSFEHLISQRKELASQIKVFAQNCSQLSHVEEHNGLARALAQLXXXXXXXXXXXXRQAEVEFYTLLELLKDYLGMIGAVKEVLNERIRQYRVWQEAESNLNKKREQKARCEISGKVDKIPAFDLEIKECLNKVDRTREDFEKISKTIKTELEAFDTTKVIDFKEGIIKVLEAMI 1352
            Y ++T+T R   +  E  V R   +FL LH  L+    +AG IIPPAP K  F +++ KL K        T  EFL+ +    + Y              LQRIA HP+   D +FR FL+ + EL        + G N K+  ++      +   ++    QKD+  +F+ ++  M   + H+ +     E LI+ RK + +       +  +++  E +  LAR  AQ + A  ++  +E R +  E   L + L  +     A K++L  R+R    ++ A  NL + R          K  +IP  + E  E   K       FE+I+   K EL+   T +V  FK+ +  + E  I
Sbjct:  120 YTVHTRT-RLQEMKPETAVVREHEEFLWLHGTLEDNENYAGFIIPPAPPKPNFDSSREKLQKLGEGEATMTKEEFLKMKHDLEQDYLAQFKKTVAMHEVFLQRIAAHPVFKNDQNFRIFLQYENELS-------VRGKNKKEQVESFWKRFTQSADEVLLSGQKDVDEFFEKEKNYMVEYNIHIKEAAAKSEKLIAARKNVVASFSKIGDSFERIARGEPNKSLARTFAQGADAMFKLKKVESRSSNDEELKLGDTLHYFARDTQAAKDLLYRRMRCLANYEAANKNLERAR---------AKNREIPKAEAEQSEACKK-------FEEITGLSKNELKELKTRRVQAFKKNLTDLAELEI 457

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Query:  327 YKINTKTNRPSFLHQEITVRRRFSDFLGLHERLKLKYLFAGCIIPPAPEKNAFGNTKLKLSK-----EDQTNSEFXXXXXXXXXXY--------------LQRIARHPLLVIDADFREFLEDDKELPKAVNTQVLSGANMKKLFKNVGDAVGKITTKMDDCDQKDI-LWFDDKQVEMDNLDRHLSQIHCSFEHLISQRKELASQIKVFAQNCSQLSHVEEHNGLARALAQLXXXXXXXXXXXXRQAEVEFYTLLELLKDYLGMIGAVKEVLNERIRQYRVWQEAESNLNKKREQKARCEISGKVDKIPAFDLEIKECLNKVDRTREDFEKISKTIKTELEAFDTTKVIDFKEGIIKVLEAMI 1352
            Y ++T+T R   +  E  V R   +FL LH  L+    +AG IIPPAP K  F +++ KL K        T  EFL+ +    + Y              LQRIA HP+   D +FR FL+ + EL        + G N K+  ++      +   ++    QKD+  +F+ ++  M   + H+ +     E LI+ RK + +       +  +++  E +  LAR  AQ + A  ++  +E R +  E   L + L  +     A K++L  R+R    ++ A  NL + R          K  +IP  + E  E   K       FE+I+   K EL+   T +V  FK+ +  + E  I
Sbjct:  120 YTVHTRT-RLQEMKPETAVVREHEEFLWLHGTLEDNENYAGFIIPPAPPKPNFDSSREKLQKLGEGEATMTKEEFLKMKHDLEQDYLAQFKKTVAMHEVFLQRIAAHPVFKNDQNFRIFLQYENELS-------VRGKNKKEQVESFWKRFTQSADEVLLSGQKDVDEFFEKEKNYMVEYNIHIKEAAAKSEKLIAARKNVVASFSKIGDSFERIARGEPNKSLARTFAQGADAMFKLKKVESRSSNDEELKLGDTLHYFARDTQAAKDLLYRRMRCLANYEAANKNLERAR---------AKNREIPKAEAEQSEACKK-------FEEITGLSKNELKELKTRRVQAFKKNLTDLAELEI 457

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BLAST of Sorting nexin-2 vs. Ensembl Celegans
Match: snx-6 (Sorting NeXin [Source:UniProtKB/TrEMBL;Acc:D9PTP8])

HSP 1 Score: 85.1149 bits (209), Expect = 1.416e-17
Identity = 97/361 (26.87%), Postives = 156/361 (43.21%), Query Frame = 3

Query:  327 YKINTKTNRPSFLHQEITVRRRFSDFLGLHERLKLKYLFAGCIIPPAPEKNAFGNTKLKLSK-----EDQTNSEFXXXXXXXXXXY--------------LQRIARHPLLVIDADFREFLEDDKELPKAVNTQVLSGANMKKLFKNVGDAVGKITTKMDDCDQKDILWFDDKQVEMDNLDRHLSQIHCSFEHLISQRKELASQIKVFAQNCSQLSHVEEHNGLARALAQLXXXXXXXXXXXXRQAEVEFYTLLELLKDYLGMIGAVKEVLNERIRQYRVWQEAESNLNKKREQKARCEISGKVDKIPAFDLEIKECLNKVDRTREDFEKISKTIKTELEAFDTTKVIDFKEGIIKVLEAMI 1352
            Y ++T+T R   +  E  V R   +FL LH  L+    +AG IIPPAP K  F +++ KL K        T  EFL+ +    + Y              LQRIA HP+   D +FR FL+ + EL      +     +  K F    D V  + +   D D+    +F+ ++  M   + H+ +     E LI+ RK + +       +  +++  E +  LAR  AQ + A  ++  +E R +  E   L + L  +     A K++L  R+R    ++ A  NL + R          K  +IP  + E  E   K       FE+I+   K EL+   T +V  FK+ +  + E  I
Sbjct:   23 YTVHTRT-RLQEMKPETAVVREHEEFLWLHGTLEDNENYAGFIIPPAPPKPNFDSSREKLQKLGEGEATMTKEEFLKMKHDLEQDYLAQFKKTVAMHEVFLQRIAAHPVFKNDQNFRIFLQYENELSVRGKNKKEQVESFWKRFTQSADEV--LLSGQKDVDE----FFEKEKNYMVEYNIHIKEAAAKSEKLIAARKNVVASFSKIGDSFERIARGEPNKSLARTFAQGADAMFKLKKVESRSSNDEELKLGDTLHYFARDTQAAKDLLYRRMRCLANYEAANKNLERAR---------AKNREIPKAEAEQSEACKK-------FEEITGLSKNELKELKTRRVQAFKKNLTDLAELEI 360

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BLAST of Sorting nexin-2 vs. Ensembl Fly
Match: Snx1 (gene:FBgn0031534 transcript:FBtr0077517)

HSP 1 Score: 322.783 bits (826), Expect = 1.025e-104
Identity = 180/418 (43.06%), Postives = 265/418 (63.40%), Query Frame = 3

Query:  168 TITRNASPPRTSVTEISN--DRVPNQRKISKTGK-FIEISVSYPEKLGSGMAAYFIYKINTKTNRPSFLHQEITVRRRFSDFLGLHERLKLKYLFAGCIIPPAPEKNAFGNTKLKLSKEDQ-----TNSEFXXXXXXXXXXYLQRIARHPLLVIDADFREFLEDDKELPKAVNTQVLSGANMKKLFKNVGDAVGKITTKMDDCDQKDILWFDDKQVEMDNLDRHLSQIHCSFEHLISQRKELASQIKVFAQNCSQLSHVEEHNGLARALAQLXXXXXXXXXXXXRQAEVEFYTLLELLKDYLGMIGAVKEVLNERIRQYRVWQEAESNLNKKREQKARCEISGKVDKIPAFDLEIKECLNKVDRTREDFEKISKTIKTELEAFDTTKVIDFKEGIIKVLEAMISSQEEIIHQWEKYIP 1397
            T+ RN S    S    S+  D  P Q  ++  G  FI I VS P+K+G GM +Y  YK+ TKTN P F   E +  RRFSDFLG+H+ L  KY+  G IIPPAP KN  G+TK+K+S +          E++E RRAALER++ R A+HP+L +D DF  FLE D+ELP++VNT  LSGA + +LF  VG+ V KIT KMD+ D     WFDDK  E+++LD +L ++H + + L++ R+EL+    + A++ + LS  EEH GL+RAL+ L+  +E+I  +   QA  +F+ L E +KDYLG+ GA+K + +ER++ ++ WQ A+  L+K+RE + R E++ + DK+     E+ E   KV R ++ F+ IS  IK E+E F+ T+V DFK  IIK +E  ++ Q++I+  WE + P
Sbjct:   39 TLDRNESDLFVSALSPSSIGDIHPLQEVLTDDGDYFISIVVSDPQKIGDGMGSYLAYKVTTKTNIPKFKRSEFSTLRRFSDFLGIHDLLVGKYMRLGRIIPPAPSKNIIGSTKVKISPQQSEPGTPMTQEWVEIRRAALERFVHRTAQHPVLRVDLDFMNFLESDQELPRSVNTSALSGAGVIRLFNKVGETVNKITYKMDENDP----WFDDKITEVESLDANLQKLHNAMKSLVTSRRELSLLTGLVAKSAAMLSTCEEHTGLSRALSNLADVEEKIELLRSEQANSDFFILAEFIKDYLGLFGAIKCIFHERVKAFQNWQYAQMQLSKRRENRGRFELANRADKLDQAQQEVDEWQGKVQRCQQQFDDISAEIKREMERFELTRVKDFKVNIIKYIEDQMAHQQQIVSYWEAFAP 452

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BLAST of Sorting nexin-2 vs. Ensembl Fly
Match: Snx1 (gene:FBgn0031534 transcript:FBtr0343238)

HSP 1 Score: 318.931 bits (816), Expect = 3.043e-103
Identity = 180/418 (43.06%), Postives = 265/418 (63.40%), Query Frame = 3

Query:  168 TITRNASPPRTSVTEISN--DRVPNQRKISKTGK-FIEISVSYPEKLGSGMAAYFIYKINTKTNRPSFLHQEITVRRRFSDFLGLHERLKLKYLFAGCIIPPAPEKNAFGNTKLKLSKEDQ-----TNSEFXXXXXXXXXXYLQRIARHPLLVIDADFREFLEDDKELPKAVNTQVLSGANMKKLFKNVGDAVGKITTKMDDCDQKDILWFDDKQVEMDNLDRHLSQIHCSFEHLISQRKELASQIKVFAQNCSQLSHVEEHNGLARALAQLXXXXXXXXXXXXRQAEVEFYTLLELLKDYLGMIGAVKEVLNERIRQYRVWQEAESNLNKKREQKARCEISGKVDKIPAFDLEIKECLNKVDRTREDFEKISKTIKTELEAFDTTKVIDFKEGIIKVLEAMISSQEEIIHQWEKYIP 1397
            T+ RN S    S    S+  D  P Q  ++  G  FI I VS P+K+G GM +Y  YK+ TKTN P F   E +  RRFSDFLG+H+ L  KY+  G IIPPAP KN  G+TK+K+S +          E++E RRAALER++ R A+HP+L +D DF  FLE D+ELP++VNT  LSGA + +LF  VG+ V KIT KMD+ D     WFDDK  E+++LD +L ++H + + L++ R+EL+    + A++ + LS  EEH GL+RAL+ L+  +E+I  +   QA  +F+ L E +KDYLG+ GA+K + +ER++ ++ WQ A+  L+K+RE + R E++ + DK+     E+ E   KV R ++ F+ IS  IK E+E F+ T+V DFK  IIK +E  ++ Q++I+  WE + P
Sbjct:   39 TLDRNESDLFVSALSPSSIGDIHPLQEVLTDDGDYFISIVVSDPQKIGDGMGSYLAYKVTTKTNIPKFKRSEFSTLRRFSDFLGIHDLLVGKYMRLGRIIPPAPSKNIIGSTKVKISPQQSEPGTPMTQEWVEIRRAALERFVHRTAQHPVLRVDLDFMNFLESDQELPRSVNTSALSGAGVIRLFNKVGETVNKITYKMDENDP----WFDDKITEVESLDANLQKLHNAMKSLVTSRRELSLLTGLVAKSAAMLSTCEEHTGLSRALSNLADVEEKIELLRSEQANSDFFILAEFIKDYLGLFGAIKCIFHERVKAFQNWQYAQMQLSKRRENRGRFELANRADKLDQAQQEVDE--GKVQRCQQQFDDISAEIKREMERFELTRVKDFKVNIIKYIEDQMAHQQQIVSYWEAFAP 450

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BLAST of Sorting nexin-2 vs. Ensembl Fly
Match: Snx6 (gene:FBgn0032005 transcript:FBtr0306170)

HSP 1 Score: 79.337 bits (194), Expect = 1.964e-15
Identity = 92/375 (24.53%), Postives = 163/375 (43.47%), Query Frame = 3

Query:  327 YKINTKTNRPSFLHQEITVRRRFSDFLGLHERLKLKYLFAGCIIPPAPEKNAFGNTKLKLSK-----EDQTNSEFXXXXXXXXXXY--------------LQRIARHPLLVIDADFREFLEDDKEL-PKAVNTQVLSGANMKKLFKNVGDAVGKITTKMDDCDQKDILWFDDKQVEMDNLDRHLSQIHCSFEHLISQRKELASQIKVFAQNCSQLSHVEEHNGLARALAQLXXXXXXXXXXXXRQAEVEFYTLLELLKDYLGMIGAVKEVLNERIRQYRVWQEAESNLNKKREQKARCEISGKVDKIPAFDLEIKECLNKVDRTREDFEKISKTIKTELEAFDTTKVIDFKEGIIKVLEAMISSQEEIIHQWEKY 1391
            + ++T+T  P F  ++  V R+  +F+ LH+R++    +AG IIPP P +  F  ++ KL +      + T  EF + +      Y              L+R+A HP+  +D   + FLE D++L  K      + G  +K L K   + +   T +    D  D  +F+++   +     HL +     E +  + K++    +  +   +QLS  E+ N +   +A+ +   E I  +E R A  +   L + L+ Y     A K +L  R+R    ++ A  NL K R +          +K     LE++E         E FE +S   K EL  F   +V  FK+ ++++      S+ EI H   +Y
Sbjct:   90 FTVHTRTTLPGFSKKDNNVVRQHEEFVWLHDRIEENDDYAGYIIPPCPPRPDFDASREKLQRLGEGEGNMTKEEFKKMKSELEAEYLATFKKTVAMHEVFLRRLASHPVFRVDQHLKVFLEYDQDLCAKPRKKMAIFGGFVKSLGKTTDEILLSATVR----DVND--FFENELQFLTEYHGHLREAALRTEKMTQRHKDVGDSHQKISNALTQLSTTEKGN-VETFVAKTAEIFERIKNLETRVASDQDLKLGDTLRYYQRDSDAAKALLIRRLRCLAAYEAANRNLEKARSK----------NKDVHAPLEVQEAETAQAEACEKFESMSACGKEELIGFRNRRVAAFKKSLVEL------SELEIKHAKTQY 441

[Close]

BLAST of Sorting nexin-2 vs. Ensembl Fly
Match: Snx6 (gene:FBgn0032005 transcript:FBtr0079631)

HSP 1 Score: 75.485 bits (184), Expect = 3.030e-14
Identity = 92/375 (24.53%), Postives = 161/375 (42.93%), Query Frame = 3

Query:  327 YKINTKTNRPSFLHQEITVRRRFSDFLGLHERLKLKYLFAGCIIPPAPEKNAFGNTKLKLSK-----EDQTNSEFXXXXXXXXXXY--------------LQRIARHPLLVIDADFREFLEDDKEL-PKAVNTQVLSGANMKKLFKNVGDAVGKITTKMDDCDQKDILWFDDKQVEMDNLDRHLSQIHCSFEHLISQRKELASQIKVFAQNCSQLSHVEEHNGLARALAQLXXXXXXXXXXXXRQAEVEFYTLLELLKDYLGMIGAVKEVLNERIRQYRVWQEAESNLNKKREQKARCEISGKVDKIPAFDLEIKECLNKVDRTREDFEKISKTIKTELEAFDTTKVIDFKEGIIKVLEAMISSQEEIIHQWEKY 1391
            + ++T+T  P F  ++  V R+  +F+ LH+R++    +AG IIPP P +  F  ++ KL +      + T  EF + +      Y              L+R+A HP+  +D   + FLE D++L  K      + G  +K L K   + +   T +    D  D  +F+++   +     HL +     E +  + K++    +  +   +QLS  E+ N +   +A+ +   E I  +E R A  +   L + L+ Y     A K +L  R+R    ++ A  NL K R        S   D   A   + + C        E FE +S   K EL  F   +V  FK+ ++++      S+ EI H   +Y
Sbjct:   90 FTVHTRTTLPGFSKKDNNVVRQHEEFVWLHDRIEENDDYAGYIIPPCPPRPDFDASREKLQRLGEGEGNMTKEEFKKMKSELEAEYLATFKKTVAMHEVFLRRLASHPVFRVDQHLKVFLEYDQDLCAKPRKKMAIFGGFVKSLGKTTDEILLSATVR----DVND--FFENELQFLTEYHGHLREAALRTEKMTQRHKDVGDSHQKISNALTQLSTTEKGN-VETFVAKTAEIFERIKNLETRVASDQDLKLGDTLRYYQRDSDAAKALLIRRLRCLAAYEAANRNLEKAR--------SKNKDVHAAETAQAEAC--------EKFESMSACGKEELIGFRNRRVAAFKKSLVEL------SELEIKHAKTQY 435

[Close]

BLAST of Sorting nexin-2 vs. Ensembl Fly
Match: Snx3 (gene:FBgn0038065 transcript:FBtr0082641)

HSP 1 Score: 48.9062 bits (115), Expect = 1.535e-6
Identity = 39/112 (34.82%), Postives = 58/112 (51.79%), Query Frame = 3

Query:  264 FIEISVSYP-EKLGSGMAAYFIYKINTKTNRPSFLHQEITVRRRFSDFLGLHERLKLKYLFAGCIIPPAPEKNAFGNTKLKLSKEDQTNSEFXXXXXXXXXXYLQRIARHPL 596
            F+EI V  P   + +G   Y  Y++  +TN P F  +E +VRRR+SDF  L   L+     +  ++PP P K A+         E   +  F+E RR  LE ++ +IA HPL
Sbjct:   32 FLEIDVVNPLTTMAAGKKRYTDYEVRMRTNLPVFKVKESSVRRRYSDFEWLRNELERD---SKIVVPPLPGK-AWKRQMPFRGDEGIFDESFIEERRKGLEAFINKIAGHPL 139

[Close]

BLAST of Sorting nexin-2 vs. Ensembl Zebrafish
Match: snx1a (sorting nexin 1a [Source:ZFIN;Acc:ZDB-GENE-060302-3])

HSP 1 Score: 310.071 bits (793), Expect = 2.357e-97
Identity = 168/383 (43.86%), Postives = 255/383 (66.58%), Query Frame = 3

Query:  267 IEISVSYPEKLGSGMAAYFIYKINTKTNRPSFLHQEITVRRRFSDFLGLHERLKLKYLFAGCIIPPAPEKNAFGNTKLKLSKEDQTNSEFXXXXXXXXXXYLQRIARHPLLVIDADFREFLEDDKELPKAVNTQVLSGANMKKLFKNVGDAVGKITTKMDDCDQKDILWFDDKQVEMDNLDRHLSQIHCSFEHLISQRKELASQIKVFAQNCSQLSHVEEHNGLARALAQLXXXXXXXXXXXXRQAEVEFYTLLELLKDYLGMIGAVKEVLNERIRQYRVWQEAESNLNKKREQKARCEISGKVDKIPAFDLEIKECLNKVDRTREDFEKISKTIKTELEAFDTTKVIDFKEGIIKVLEAMISSQEEIIHQWEKYIPDTAGIS 1415
            + +S++ PEK+G GM AY +YK++T+T+   F  +  TVRRRFSDFLGL+E+L  K+   G I+PP PEK+  G TK+K+ KED +++EF+ERRRAALERYLQR+  HP L+ D D REFLE + ELP+AV+TQ LSGA   K+     DAV K+T KM++ D    +WFD+K  +++N ++ L ++H   E L++ RKEL+     FA++ + L   E++  L+RAL+QL+  ++ I  +   QA  +F+T  ELL DY+ ++GAV+   ++R++ ++ WQ+AES L KKRE +A+   + K DK+     EI E   KV +   DFE+IS T++ ++  FD  K  DFK  IIK LE+++ SQ+++I  WE ++P+   I+
Sbjct:  282 LNVSITNPEKVGDGMNAYMVYKVSTQTSLSMFRSKTFTVRRRFSDFLGLYEKLSEKHSQNGYIVPPPPEKSIMGMTKVKVGKEDPSSAEFVERRRAALERYLQRVVSHPSLLQDPDVREFLEKE-ELPRAVSTQTLSGAGFLKMLNKATDAVSKMTIKMNEQD----VWFDEKIQDVENEEQLLRKLHVMVESLVNHRKELSGNTAAFAKSVAMLGSSEDNTALSRALSQLAEVEDRIEQLHRDQAANDFFTFAELLADYIRLLGAVRGCFDQRMKAWQRWQDAESMLQKKREAEAKLLWANKPDKLQQAKDEIAEWEAKVTQYERDFERISATVQKDVIRFDKEKARDFKRQIIKYLESLLHSQQQLIKYWEAFLPEAKAIA 659

[Close]

BLAST of Sorting nexin-2 vs. Ensembl Zebrafish
Match: snx1b (sorting nexin 1b [Source:ZFIN;Acc:ZDB-GENE-050913-82])

HSP 1 Score: 275.018 bits (702), Expect = 8.713e-86
Identity = 149/348 (42.82%), Postives = 234/348 (67.24%), Query Frame = 3

Query:  267 IEISVSYPEKLGSGMAAYFIYKINTKTNRPSFLHQEITVRRRFSDFLGLHERLKLKYLFAGCIIPPAPEKNAFGNTKLKLSKEDQTNSEFXXXXXXXXXXYLQRIARHPLLVIDADFREFLEDDKELPKAVNTQVLSGANMKKLFKNVGDAVGKITTKMDDCDQKDILWFDDKQVEMDNLDRHLSQIHCSFEHLISQRKELASQIKVFAQNCSQLSHVEEHNGLARALAQLXXXXXXXXXXXXRQAEVEFYTLLELLKDYLGMIGAVKEVLNERIRQYRVWQEAESNLNKKREQKARCEISGKVDKIPAFDLEIKECLNKVDRTREDFEKISKTIKTELEAFDTTKVI 1310
            + I+V+ PEK+G GM AY  YK++T+T  P F ++  TVRRRFSDFLGL+E++  K    GCIIPPAP+K+  G TK+K+ KED +++EF+E+RRAALERYLQR+  HP L+ D D REFLE D ELP+AVNTQ LSG  + K+     DAV K+T K+++ D     WF+ K  E++N ++ L ++H + + L++ RKEL     VF+++ + L  VEE++ L+RAL+QL+  ++++  + ++QA  +F+ L ELL DY+ ++GAV+    +R++ ++  QEA+  L KKRE +A+   + K +K+     +I E  +KV +   DFE+++ T++ E+  F+   V+
Sbjct:  147 LNIAVTNPEKIGDGMTAYMSYKVSTQTTLPMFANKTFTVRRRFSDFLGLYEKMSAKNSLMGCIIPPAPQKSVVGMTKVKVGKEDSSSAEFVEKRRAALERYLQRVVAHPSLLQDPDVREFLERD-ELPRAVNTQTLSGPGLLKMINRASDAVNKMTIKINESDN----WFESKLQEVENEEQLLRRLHAAVDSLVNHRKELCINTAVFSKSVAMLGSVEENSALSRALSQLAEVEDKMEQLHQQQAFSDFFILAELLADYVRLLGAVRCCFEQRMKVWQRLQEAQITLQKKREAEAKLLWANKPEKLQQAKDDINEWESKVSQYERDFERVTCTVRKEVLRFEVRHVV 489

[Close]

BLAST of Sorting nexin-2 vs. Ensembl Zebrafish
Match: snx1b (sorting nexin 1b [Source:ZFIN;Acc:ZDB-GENE-050913-82])

HSP 1 Score: 273.478 bits (698), Expect = 3.156e-85
Identity = 148/343 (43.15%), Postives = 232/343 (67.64%), Query Frame = 3

Query:  267 IEISVSYPEKLGSGMAAYFIYKINTKTNRPSFLHQEITVRRRFSDFLGLHERLKLKYLFAGCIIPPAPEKNAFGNTKLKLSKEDQTNSEFXXXXXXXXXXYLQRIARHPLLVIDADFREFLEDDKELPKAVNTQVLSGANMKKLFKNVGDAVGKITTKMDDCDQKDILWFDDKQVEMDNLDRHLSQIHCSFEHLISQRKELASQIKVFAQNCSQLSHVEEHNGLARALAQLXXXXXXXXXXXXRQAEVEFYTLLELLKDYLGMIGAVKEVLNERIRQYRVWQEAESNLNKKREQKARCEISGKVDKIPAFDLEIKECLNKVDRTREDFEKISKTIKTELEAFD 1295
            + I+V+ PEK+G GM AY  YK++T+T  P F ++  TVRRRFSDFLGL+E++  K    GCIIPPAP+K+  G TK+K+ KED +++EF+E+RRAALERYLQR+  HP L+ D D REFLE D ELP+AVNTQ LSG  + K+     DAV K+T K+++ D     WF+ K  E++N ++ L ++H + + L++ RKEL     VF+++ + L  VEE++ L+RAL+QL+  ++++  + ++QA  +F+ L ELL DY+ ++GAV+    +R++ ++  QEA+  L KKRE +A+   + K +K+     +I E  +KV +   DFE+++ T++ E+  F+
Sbjct:  147 LNIAVTNPEKIGDGMTAYMSYKVSTQTTLPMFANKTFTVRRRFSDFLGLYEKMSAKNSLMGCIIPPAPQKSVVGMTKVKVGKEDSSSAEFVEKRRAALERYLQRVVAHPSLLQDPDVREFLERD-ELPRAVNTQTLSGPGLLKMINRASDAVNKMTIKINESDN----WFESKLQEVENEEQLLRRLHAAVDSLVNHRKELCINTAVFSKSVAMLGSVEENSALSRALSQLAEVEDKMEQLHQQQAFSDFFILAELLADYVRLLGAVRCCFEQRMKVWQRLQEAQITLQKKREAEAKLLWANKPEKLQQAKDDINEWESKVSQYERDFERVTCTVRKEVLRFE 484

[Close]

BLAST of Sorting nexin-2 vs. Ensembl Zebrafish
Match: snx2 (sorting nexin 2 [Source:ZFIN;Acc:ZDB-GENE-051120-45])

HSP 1 Score: 209.534 bits (532), Expect = 9.557e-61
Identity = 144/460 (31.30%), Postives = 233/460 (50.65%), Query Frame = 3

Query:   87 DDDDIFEEAMENTDEFGVQTEIRLD----EPTITRNASPPRTSVTEIS---------NDRVPNQ---RKISKTGKFIEISVSYPEKLGSGMAAYFIYKINTKTNRPSFLHQEITVRRRFSDFLGLHERLKLKYL-FAGCIIPPAPEKNAFGNTKLKLSKEDQTNSEFXXXXXXXXXXYLQRIARHPLLVIDADFREFLEDDKELPKAVNTQVLSGANMKKLFKNVGDAVGKITTKMDDCDQKDILWFDDKQVEMDNLDRHLSQIHCSFEHLISQRKELASQIKVFAQNCSQLSHVEEHNGLARALAQLXXXXXXXXXXXXRQAEVEFYTLLELLKDYLGMIGAVKEVLNERIRQYRVWQEAESNLNKKREQKARCEISGKVDKIPAFDLEIKECLNKVDRTREDFEKISKTIKTELEAFDTTKVIDFKEGIIKVLEAMISSQEEIIHQWEKYIPDTAGIS 1415
            D +D+F EA E         E+ LD    +P ++   SP  T VT +S          DR P +    + S+    I+ISVS PEK+G GM AY +YK+ TK+    F   E+ V   ++ F G      L+YL  + C++ P  E +    + +    +         +R A +  YL R  +HP L+ D D  +FLE   ELP+AV+TQ LSGA + ++     DAV K+T KM++ D     WF++KQ + +NLD  L ++H S E L+  RK L   +  F      L+   E+  LA+   +            +R     F     +L D   +   ++ V ++R++ +  WQ+A+  L +KRE +A+ + + K DK+     EIKE   KV +   DFE+ISK I+ E+  F+  +V DF+  ++K LE+++ +Q+++I  WE ++P+   I+
Sbjct:   62 DTEDLFAEATE---------EVSLDSPERQPILSDGPSPAITPVTPVSIGSRVELGAFDRSPEEDEDEQESRDTLDIQISVSDPEKVGDGMNAYMVYKVTTKSCLSVFSRSEVCVYTDYTIFQGCVCVCYLQYLRVSVCVLSPVFEMSVCVLSPVFEGVQLMNRINIRGKRGADISLYLMRTVKHPALLKDPDVLQFLES-SELPRAVSTQALSGAGILRMVNKAADAVNKMTIKMNEADA----WFEEKQQQFENLDLQLRKLHASVESLVCHRKALCLFLASFVSESGVLNKSFEYTSLAKFCFE-HPNVSAEMETHQRNTMALFLDESVILNDSSQLCVRIRGVFDQRMKTWAKWQDAQVMLQRKREAEAKLQYANKPDKLQQAKDEIKEWEGKVQQGERDFEQISKNIRREVGRFEKDRVKDFRIVVVKYLESLVHTQQQLIKYWEAFLPEAKAIA 506

[Close]

BLAST of Sorting nexin-2 vs. Ensembl Zebrafish
Match: snx5 (sorting nexin 5 [Source:ZFIN;Acc:ZDB-GENE-040426-2857])

HSP 1 Score: 80.4925 bits (197), Expect = 7.420e-16
Identity = 85/362 (23.48%), Postives = 160/362 (44.20%), Query Frame = 3

Query:  327 YKINTKTNRPSFLHQEITVRRRFSDFLGLHERLKLKYLFAGCIIPPAPEKNAFGNTKLKLSK-----EDQTNSEFXXXXXXXXXXY--------------LQRIARHPLLVIDADFREFLEDDKELP-KAVNTQVLSGANMKKLFKNVGDAVGKITTKMDDCDQKDILWFDDKQVEMDNLDRHLSQIHCSFEHLISQRKELASQIKVFAQNCSQLSHVEEHNGLARALAQLXXXXXXXXXXXXRQAEVEFYTLLELLKDYLGMIGAVKEVLNERIRQYRVWQEAESNLNKKREQKARCEISGKVDKIPAFDLEIKECLNKVDRTREDFEKISKTIKTELEAFDTTKVIDFKEGIIKVLEAMI 1352
            + ++TKT   SF   + +V R+  DF+ LH+ +     +AG IIPPAP K  F   + K+ K        T  E+ + ++     Y              LQR++ HP    D +F  FLE D++L  +  N + + G   K + K   + +     ++D+       +F+ ++  + +    +       E +    K +A      +   + ++  + ++   + L +     E++  +E+R A  +   L ELL+ Y   I A K++L  R R    ++ +   L+K R       + GK   +P  +   K+CL K DR       +S++ K EL +F   +V+ F++ +I++ E  I
Sbjct:   42 FTVHTKTTLSSFQKPDFSVPRQHEDFIWLHDAIVETEEYAGLIIPPAPPKPDFEGPREKMHKLGEGESSMTKEEYAKMKQELEAEYLAVFKKTVQVHEVFLQRLSSHPSFSKDRNFHIFLEYDQDLSVRRKNAKEMFGGFFKNMVKTADEVLISGVKEVDE-------FFEQEKTFLLDYSNKIKDSTAKAEKMTRSHKNVADDYNHISGALNSVA-ADNNSAFKKHLEKCVEVFEKLRKVEDRVASDQELKLTELLRYYTRDIQAAKDLLYRRARALADYENSNKALDKAR-------LKGK--DVPQAEENQKQCLQKFDR-------LSESGKKELTSFKARRVVAFRKNLIEMTELEI 379

[Close]

BLAST of Sorting nexin-2 vs. Ensembl Xenopus
Match: SNX2 (sorting nexin 2 [Source:NCBI gene;Acc:100492702])

HSP 1 Score: 337.806 bits (865), Expect = 1.554e-109
Identity = 196/466 (42.06%), Postives = 288/466 (61.80%), Query Frame = 3

Query:   87 DDDDIFEEAMENTDEFGVQTEIRLDEP----TITRNASPPRTSVTEISNDRVPNQRKISKTGKFI-------------------EISVSYPEKLGSGMAAYFIYKINTKTNRPSFLHQEITVRRRFSDFLGLHERLKLKYLFAGCIIPPAPEKNAFGNTKLKLSKEDQTNSEFXXXXXXXXXXYLQRIARHPLLVIDADFREFLEDDKELPKAVNTQVLSGANMKKLFKNVGDAVGKITTKMDDCDQKDILWFDDKQVEMDNLDRHLSQIHCSFEHLISQRKELASQIKVFAQNCSQLSHVEEHNGLARALAQLXXXXXXXXXXXXRQAEVEFYTLLELLKDYLGMIGAVKEVLNERIRQYRVWQEAESNLNKKREQKARCEISGKVDKIPAFDLEIKECLNKVDRTREDFEKISKTIKTELEAFDTTKVIDFKEGIIKVLEAMISSQEEIIHQWEKYIPDTAGIS 1415
            D +D+F EA +         E+ LD P     ++   SP  T VT  S   +P    IS +   I                   EI VS PEK+G GM AY  YK+ TKT+   F   E +VRRRFSDFLGLH +L  KY+  G I+PPAPEK+  G TK+K+ KED +++EF+E+RRAALERYLQR  +HP L+ D D R+FLE   ELP+AV+TQ LSGA + ++     DAV K+T KM++ D     WF++KQ + +NLD+ L ++H + E L+  RKEL++    FA++ + L + E+H  L+RAL+QL+  +E+I  + + QA  +FY   ELL DY+ +I AVK V ++R++ ++ WQ+A+ NL KK+E +A+ +IS K DK+     EI+E   KV +   DF++ISKTI+ E+  F+  +V DFK  IIK LE+++ +Q+++I  WE ++P+   I+
Sbjct:   69 DREDLFAEATD---------EVSLDSPERDLILSSEPSPAITPVTPTSL-IMPRMETISISAPVIYDRSTDEIEEEANGDAFDVEIGVSDPEKVGDGMNAYMAYKVTTKTSLSMFNKNEFSVRRRFSDFLGLHSKLATKYMHIGYIVPPAPEKSIVGMTKVKVGKEDSSSNEFVEKRRAALERYLQRTVKHPTLLQDPDLRQFLES-SELPRAVSTQALSGAGLLRMVNKAADAVNKMTIKMNESDA----WFEEKQQQFENLDQQLRKLHGNVESLVCHRKELSANTAAFAKSAAMLGNSEDHTALSRALSQLAEVEEKIDQLHQDQAFADFYLFTELLSDYIRLIAAVKGVFDQRMKCWQKWQDAQVNLQKKQEAEAKLQISNKPDKLQQAKDEIREWEAKVQQGERDFDQISKTIRKEVGRFEKERVRDFKSVIIKYLESLVRTQQQLIKYWEAFLPEAKAIA 519

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BLAST of Sorting nexin-2 vs. Ensembl Xenopus
Match: SNX2 (sorting nexin 2 [Source:NCBI gene;Acc:100492702])

HSP 1 Score: 326.635 bits (836), Expect = 3.307e-105
Identity = 196/470 (41.70%), Postives = 288/470 (61.28%), Query Frame = 3

Query:   87 DDDDIFEEAMENTDEFGVQTEIRLDEP----TITRNASPPRTSVTEISNDRVPNQRKISKTGKFI-------------------EISVSYPEKLGSGMAAYFIYKINTKTNRPSFLHQEITVRRRFSDFLGLHERLKLKYLFAGCIIPPAPEKNAFGNTKLKLSKEDQTNSEFXXXXXXXXXXYLQRIARHPLLVIDADFREFLEDDKELPKAVNTQVLSGANMKKLFKNVGDAVGKITTKMDDCDQKDILWFDDKQVEMDNLDRHLSQIHCSFEHLISQRKELASQIKVFAQNCSQLSHVEEHNGLARALAQLXXXXXXXXXXXXRQAEVEFYTLLELLKDYLGMIGAVKEVLNERIRQYRVWQEAESNLNKKREQKARCEISGKVDKIP----AFDLEIKECLNKVDRTREDFEKISKTIKTELEAFDTTKVIDFKEGIIKVLEAMISSQEEIIHQWEKYIPDTAGIS 1415
            D +D+F EA +         E+ LD P     ++   SP  T VT  S   +P    IS +   I                   EI VS PEK+G GM AY  YK+ TKT+   F   E +VRRRFSDFLGLH +L  KY+  G I+PPAPEK+  G TK+K+ KED +++EF+E+RRAALERYLQR  +HP L+ D D R+FLE   ELP+AV+TQ LSGA + ++     DAV K+T KM++ D     WF++KQ + +NLD+ L ++H + E L+  RKEL++    FA++ + L + E+H  L+RAL+QL+  +E+I  + + QA  +FY   ELL DY+ +I AVK V ++R++ ++ WQ+A+ NL KK+E +A+ +IS K DK+         EI+E   KV +   DF++ISKTI+ E+  F+  +V DFK  IIK LE+++ +Q+++I  WE ++P+   I+
Sbjct:   69 DREDLFAEATD---------EVSLDSPERDLILSSEPSPAITPVTPTSL-IMPRMETISISAPVIYDRSTDEIEEEANGDAFDVEIGVSDPEKVGDGMNAYMAYKVTTKTSLSMFNKNEFSVRRRFSDFLGLHSKLATKYMHIGYIVPPAPEKSIVGMTKVKVGKEDSSSNEFVEKRRAALERYLQRTVKHPTLLQDPDLRQFLE-SSELPRAVSTQALSGAGLLRMVNKAADAVNKMTIKMNESDA----WFEEKQQQFENLDQQLRKLHGNVESLVCHRKELSANTAAFAKSAAMLGNSEDHTALSRALSQLAEVEEKIDQLHQDQAFADFYLFTELLSDYIRLIAAVKGVFDQRMKCWQKWQDAQVNLQKKQEAEAKLQISNKPDKLQQAKDEIREEIEEWEAKVQQGERDFDQISKTIRKEVGRFEKERVRDFKSVIIKYLESLVRTQQQLIKYWEAFLPEAKAIA 523

[Close]

BLAST of Sorting nexin-2 vs. Ensembl Xenopus
Match: SNX2 (sorting nexin 2 [Source:NCBI gene;Acc:100492702])

HSP 1 Score: 322.783 bits (826), Expect = 9.764e-104
Identity = 191/450 (42.44%), Postives = 278/450 (61.78%), Query Frame = 3

Query:   87 DDDDIFEEAMENTDEFGVQTEIRLDEP----TITRNASPPRTSVTEISNDRVPNQRKISKTGKFI-------------------EISVSYPEKLGSGMAAYFIYKINTKTNRPSFLHQEITVRRRFSDFLGLHERLKLKYLFAGCIIPPAPEKNAFGNTKLKLSKEDQTNSEFXXXXXXXXXXYLQRIARHPLLVIDADFREFLEDDKELPKAVNTQVLSGANMKKLFKNVGDAVGKITTKMDDCDQKDILWFDDKQVEMDNLDRHLSQIHCSFEHLISQRKELASQIKVFAQNCSQLSHVEEHNGLARALAQLXXXXXXXXXXXXRQAEVEFYTLLELLKDYLGMIGAVKEVLNERIRQYRVWQEAESNLNKKREQKARCEISGKVDKIPAFDLEIKECLNKVDRTREDFEKISKTIKTELEAFDTTKVIDFKEGIIKVLEAMISSQEE 1367
            D +D+F EA +         E+ LD P     ++   SP  T VT  S   +P    IS +   I                   EI VS PEK+G GM AY  YK+ TKT+   F   E +VRRRFSDFLGLH +L  KY+  G I+PPAPEK+  G TK+K+ KED +++EF+E+RRAALERYLQR  +HP L+ D D R+FLE   ELP+AV+TQ LSGA + ++     DAV K+T KM++ D     WF++KQ + +NLD+ L ++H + E L+  RKEL++    FA++ + L + E+H  L+RAL+QL+  +E+I  + + QA  +FY   ELL DY+ +I AVK V ++R++ ++ WQ+A+ NL KK+E +A+ +IS K DK+     EI+E   KV +   DF++ISKTI+ E+  F+  +V DFK  IIK LE+++ +Q++
Sbjct:   69 DREDLFAEATD---------EVSLDSPERDLILSSEPSPAITPVTPTSL-IMPRMETISISAPVIYDRSTDEIEEEANGDAFDVEIGVSDPEKVGDGMNAYMAYKVTTKTSLSMFNKNEFSVRRRFSDFLGLHSKLATKYMHIGYIVPPAPEKSIVGMTKVKVGKEDSSSNEFVEKRRAALERYLQRTVKHPTLLQDPDLRQFLES-SELPRAVSTQALSGAGLLRMVNKAADAVNKMTIKMNESDA----WFEEKQQQFENLDQQLRKLHGNVESLVCHRKELSANTAAFAKSAAMLGNSEDHTALSRALSQLAEVEEKIDQLHQDQAFADFYLFTELLSDYIRLIAAVKGVFDQRMKCWQKWQDAQVNLQKKQEAEAKLQISNKPDKLQQAKDEIREWEAKVQQGERDFDQISKTIRKEVGRFEKERVRDFKSVIIKYLESLVRTQQQ 503

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BLAST of Sorting nexin-2 vs. Ensembl Xenopus
Match: SNX2 (sorting nexin 2 [Source:NCBI gene;Acc:100492702])

HSP 1 Score: 312.383 bits (799), Expect = 5.340e-100
Identity = 186/435 (42.76%), Postives = 273/435 (62.76%), Query Frame = 3

Query:   87 DDDDIFEEAMENTDEFGVQTEIRLDEP----TITRNASPPRTSVTEISNDRVP----NQRKISKTGKFIEISVSYPEKLGSGMAAYFIYKINTKTNRPSFLHQEITVRRRFSDFLGLHERLKLKYLFAGCIIPPAPEKNAFGNTKLKLSKEDQTNSEFXXXXXXXXXXYLQRIARHPLLVIDADFREFLEDDKELPKAVNTQVLSGANMKKLFKNVGDAVGKITTKMDDCDQKDILWFDDKQVEMDNLDRHLSQIHCSFEHLISQRKELASQIKVFAQNCSQLSHVEEHNGLARALAQLXXXXXXXXXXXXRQAEVEFYTLLELLKDYLGMIGAVKEVLNERIRQYRVWQEAESNLNKKREQKARCEISGKVDKIPAFDLEIKECLNKVDRTREDFEKISKTIKTELEAFDTTKVIDFKEGIIKVLEAMISSQEE 1367
            D +D+F EA +         E+ LD P     ++   SP  T VT  S   VP    N ++   T  F+         LG GM AY  YK+ TKT+   F   E +VRRRFSDFLGLH +L  KY+  G I+PPAPEK+  G TK+K+ KED +++EF+E+RRAALERYLQR  +HP L+ D D R+FLE   ELP+AV+TQ LSGA + ++     DAV K+T KM++ D     WF++KQ + +NLD+ L ++H + E L+  RKEL++    FA++ + L + E+H  L+RAL+QL+  +E+I  + + QA  +FY   ELL DY+ +I AVK V ++R++ ++ WQ+A+ NL KK+E +A+ +IS K DK+     EI+E   KV +   DF++ISKTI+ E+  F+  +V DFK  IIK LE+++ +Q++
Sbjct:   69 DREDLFAEATD---------EVSLDSPERDLILSSEPSPAITPVTPTSLIIVPLGVYNIKQYILTFCFL--------FLGDGMNAYMAYKVTTKTSLSMFNKNEFSVRRRFSDFLGLHSKLATKYMHIGYIVPPAPEKSIVGMTKVKVGKEDSSSNEFVEKRRAALERYLQRTVKHPTLLQDPDLRQFLESS-ELPRAVSTQALSGAGLLRMVNKAADAVNKMTIKMNESDA----WFEEKQQQFENLDQQLRKLHGNVESLVCHRKELSANTAAFAKSAAMLGNSEDHTALSRALSQLAEVEEKIDQLHQDQAFADFYLFTELLSDYIRLIAAVKGVFDQRMKCWQKWQDAQVNLQKKQEAEAKLQISNKPDKLQQAKDEIREWEAKVQQGERDFDQISKTIRKEVGRFEKERVRDFKSVIIKYLESLVRTQQQ 481

[Close]

BLAST of Sorting nexin-2 vs. Ensembl Xenopus
Match: SNX2 (sorting nexin 2 [Source:NCBI gene;Acc:100492702])

HSP 1 Score: 306.99 bits (785), Expect = 4.096e-99
Identity = 166/357 (46.50%), Postives = 244/357 (68.35%), Query Frame = 3

Query:  297 LGSGMAAYFIYKINTKTNRPSFLHQEITVRRRFSDFLGLHERLKLKYLFAGCIIPPAPEKNAFGNTKLKLSKEDQTNSEFXXXXXXXXXXYLQRIARHPLLVIDADFREFLEDDKELPKAVNTQVLSGANMKKLFKNVGDAVGKITTKMDDCDQKDILWFDDKQVEMDNLDRHLSQIHCSFEHLISQRKELASQIKVFAQNCSQLSHVEEHNGLARALAQLXXXXXXXXXXXXRQAEVEFYTLLELLKDYLGMIGAVKEVLNERIRQYRVWQEAESNLNKKREQKARCEISGKVDKIPAFDLEIKECLNKVDRTREDFEKISKTIKTELEAFDTTKVIDFKEGIIKVLEAMISSQEE 1367
            LG GM AY  YK+ TKT+   F   E +VRRRFSDFLGLH +L  KY+  G I+PPAPEK+  G TK+K+ KED +++EF+E+RRAALERYLQR  +HP L+ D D R+FLE   ELP+AV+TQ LSGA + ++     DAV K+T KM++ D     WF++KQ + +NLD+ L ++H + E L+  RKEL++    FA++ + L + E+H  L+RAL+QL+  +E+I  + + QA  +FY   ELL DY+ +I AVK V ++R++ ++ WQ+A+ NL KK+E +A+ +IS K DK+     EI+E   KV +   DF++ISKTI+ E+  F+  +V DFK  IIK LE+++ +Q++
Sbjct:   38 LGDGMNAYMAYKVTTKTSLSMFNKNEFSVRRRFSDFLGLHSKLATKYMHIGYIVPPAPEKSIVGMTKVKVGKEDSSSNEFVEKRRAALERYLQRTVKHPTLLQDPDLRQFLESS-ELPRAVSTQALSGAGLLRMVNKAADAVNKMTIKMNESDA----WFEEKQQQFENLDQQLRKLHGNVESLVCHRKELSANTAAFAKSAAMLGNSEDHTALSRALSQLAEVEEKIDQLHQDQAFADFYLFTELLSDYIRLIAAVKGVFDQRMKCWQKWQDAQVNLQKKQEAEAKLQISNKPDKLQQAKDEIREWEAKVQQGERDFDQISKTIRKEVGRFEKERVRDFKSVIIKYLESLVRTQQQ 389

[Close]

BLAST of Sorting nexin-2 vs. Ensembl Mouse
Match: Snx2 (sorting nexin 2 [Source:MGI Symbol;Acc:MGI:1915054])

HSP 1 Score: 338.576 bits (867), Expect = 6.377e-110
Identity = 199/472 (42.16%), Postives = 289/472 (61.23%), Query Frame = 3

Query:   72 VSTMTDDD--DIFEEAMENTDEFGVQTEIRLDEP----TITRNASPPRTSVTEIS----------------NDRVPNQRKISKTGKF--IEISVSYPEKLGSGMAAYFIYKINTKTNRPSFLHQEITVRRRFSDFLGLHERLKLKYLFAGCIIPPAPEKNAFGNTKLKLSKEDQTNSEFXXXXXXXXXXYLQRIARHPLLVIDADFREFLEDDKELPKAVNTQVLSGANMKKLFKNVGDAVGKITTKMDDCDQKDILWFDDKQVEMDNLDRHLSQIHCSFEHLISQRKELASQIKVFAQNCSQLSHVEEHNGLARALAQLXXXXXXXXXXXXRQAEVEFYTLLELLKDYLGMIGAVKEVLNERIRQYRVWQEAESNLNKKREQKARCEISGKVDKIPAFDLEIKECLNKVDRTREDFEKISKTIKTELEAFDTTKVIDFKEGIIKVLEAMISSQEEIIHQWEKYIPDTAGIS 1415
            V  + DDD  D+F EA E         E+ LD P     ++   SP  T VT  +                 DR  ++ +    G    IEI VS PEK+G GM AY  Y++ TKT+   F   E +V+RRFSDFLGLH +L  KYL  G I+PPAPEK+  G TK+K+ KED +++EF+E+RRAALERYLQR  +HP L+ D D R+FLE   ELP+AVNTQ LSGA + ++     DAV K+T KM++ D     WF++KQ + +NLD+ L ++H S E L+  RKEL++    FA++ + L + E+H  L+RAL+QL+  +E+I  + + QA  +FY   ELL DY+ +I AVK V + R++ ++ W++A+  L KKRE +A+  ++ K DKI     EI+E   KV +   DFE+ISKTI+ E+  F+  +V DFK  IIK LE+++ +Q+++I  WE ++P+   I+
Sbjct:   62 VEVVLDDDREDLFAEATE---------EVSLDSPERELILSSEPSPAVTPVTPTTLIAPRIESKSISAPVIFDRSRDEIEEEANGDIFDIEIGVSDPEKVGDGMNAYMAYRVTTKTSLSMFSKSEFSVKRRFSDFLGLHSKLASKYLHVGYIVPPAPEKSIVGMTKVKVGKEDSSSTEFVEKRRAALERYLQRTVKHPTLLQDPDLRQFLESS-ELPRAVNTQALSGAGILRMVNKAADAVNKMTIKMNESDA----WFEEKQQQFENLDQQLRKLHASVEALVCHRKELSANTAAFAKSAAMLGNSEDHTALSRALSQLAEVEEKIDQLHQEQAFADFYMFSELLSDYIRLIAAVKGVFDHRMKCWQKWEDAQITLLKKRETEAKMMVANKPDKIQQAKNEIREWEAKVQQGERDFEQISKTIRKEVGRFEKERVKDFKAVIIKYLESLVQTQQQLIKYWEAFLPEAKAIA 519

[Close]

BLAST of Sorting nexin-2 vs. Ensembl Mouse
Match: Snx1 (sorting nexin 1 [Source:MGI Symbol;Acc:MGI:1928395])

HSP 1 Score: 299.671 bits (766), Expect = 8.066e-95
Identity = 161/383 (42.04%), Postives = 252/383 (65.80%), Query Frame = 3

Query:  267 IEISVSYPEKLGSGMAAYFIYKINTKTNRPSFLHQEITVRRRFSDFLGLHERLKLKYLFAGCIIPPAPEKNAFGNTKLKLSKEDQTNSEFXXXXXXXXXXYLQRIARHPLLVIDADFREFLEDDKELPKAVNTQVLSGANMKKLFKNVGDAVGKITTKMDDCDQKDILWFDDKQVEMDNLDRHLSQIHCSFEHLISQRKELASQIKVFAQNCSQLSHVEEHNGLARALAQLXXXXXXXXXXXXRQAEVEFYTLLELLKDYLGMIGAVKEVLNERIRQYRVWQEAESNLNKKREQKARCEISGKVDKIPAFDLEIKECLNKVDRTREDFEKISKTIKTELEAFDTTKVIDFKEGIIKVLEAMISSQEEIIHQWEKYIPDTAGIS 1415
            + + ++ PEK+G GM AY  YK+ T+T+ P F  ++  V+RRFSDFLGL+E+L  K+   G I+PP PEK+  G TK+K+ KED +++EFLE+RRAALERYLQRI  HP ++ D D REFLE + ELP+AV TQ LSGA + K+F    DAV K+T KM++ D    +WF++K  E++  ++ L ++H   E L++ RKELA    +FA++ + L   E++  L+RAL+QL+  +E+I  + + QA  +F+ L ELL DY+ ++  V+   ++R++ ++ WQ+A++ L KKRE +AR   + K DK+     EI E  ++V +   DFE+IS  ++ E+  F+  K  DFK  ++K LE ++ SQ+++   WE ++P+   IS
Sbjct:  144 LTVGITDPEKIGDGMNAYVAYKVTTQTSLPMFRSRQFAVKRRFSDFLGLYEKLSEKHSQNGFIVPPPPEKSLIGMTKVKVGKEDSSSAEFLEKRRAALERYLQRIVNHPTMLQDPDVREFLEKE-ELPRAVGTQALSGAGLLKMFNKATDAVSKMTIKMNESD----IWFEEKLQEVECEEQRLRKLHAVVETLVNHRKELALNTALFAKSLAMLGSSEDNTALSRALSQLAEVEEKIEQLHQEQANNDFFLLAELLSDYIRLLAIVRAAFDQRMKTWQRWQDAQATLQKKRESEARLLWANKPDKLQQAKDEITEWESRVTQYERDFERISTVVRKEVTRFEKEKSKDFKNHVMKYLETLLHSQQQLAKYWEAFLPEAKAIS 521

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BLAST of Sorting nexin-2 vs. Ensembl Mouse
Match: Snx1 (sorting nexin 1 [Source:MGI Symbol;Acc:MGI:1928395])

HSP 1 Score: 98.5969 bits (244), Expect = 2.396e-23
Identity = 43/90 (47.78%), Postives = 64/90 (71.11%), Query Frame = 3

Query:  267 IEISVSYPEKLGSGMAAYFIYKINTKTNRPSFLHQEITVRRRFSDFLGLHERLKLKYLFAGCIIPPAPEKNAFGNTKLKLSKEDQTNSEF 536
            + + ++ PEK+G GM AY  YK+ T+T+ P F  ++  V+RRFSDFLGL+E+L  K+   G I+PP PEK+  G TK+K+ KED +++EF
Sbjct:   96 LTVGITDPEKIGDGMNAYVAYKVTTQTSLPMFRSRQFAVKRRFSDFLGLYEKLSEKHSQNGFIVPPPPEKSLIGMTKVKVGKEDSSSAEF 185

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BLAST of Sorting nexin-2 vs. Ensembl Mouse
Match: Snx5 (sorting nexin 5 [Source:MGI Symbol;Acc:MGI:1916428])

HSP 1 Score: 82.0333 bits (201), Expect = 2.627e-16
Identity = 88/362 (24.31%), Postives = 163/362 (45.03%), Query Frame = 3

Query:  327 YKINTKTNRPSFLHQEITVRRRFSDFLGLHERLKLKYLFAGCIIPPAPEKNAFGNTKLKLSKEDQ-----TNSEFXXXXXXXXXXY--------------LQRIARHPLLVIDADFREFLEDDKELP-KAVNTQVLSGANMKKLFKNVGDAVGKITTKMDDCDQKDILWFDDKQVEMDNLDRHLSQIHCSFEHLISQRKELASQIKVFAQNCSQLSHVEEHNGLARALAQLXXXXXXXXXXXXRQAEVEFYTLLELLKDYLGMIGAVKEVLNERIRQYRVWQEAESNLNKKREQKARCEISGKVDKIPAFDLEIKECLNKVDRTREDFEKISKTIKTELEAFDTTKVIDFKEGIIKVLEAMI 1352
            + ++TKT   +F   E +V R+  DF+ LH+ L     +AG IIPPAP K  F   + K+ K  +     T  EF + ++     Y              LQR++ HP+L  D +F  FLE D++L  +  NT+ + G   K + K+  + +     ++DD       +F+ ++  + N    +       + +    K +A    +    C     +EE   + + L +++   E++  +E R +  E   L ELL+ Y+  I A K++L  R +    ++ +   L+K R +    +++         +   +EC  K       FE++S++ K EL  F   +V  F++ +I++ E  I
Sbjct:   47 FTVHTKTTLSTFQSPEFSVTRQHEDFVWLHDTLTETTDYAGLIIPPAPTKPDFDGPREKMQKLGEGEGSMTKEEFAKMKQELEAEYLAVFKKTVSTHEVFLQRLSSHPVLSKDRNFHVFLEYDQDLSVRRKNTKEMFGGFFKSVVKSADEVLFSGVKEVDD-------FFEQEKNFLINYYNRIKDSCAKADKMTRSHKNVADDY-IHTAACLHSLALEEPTVIKKYLLKVAELFEKLRKVEGRVSSDEDLKLTELLRYYMLNIEAAKDLLYRRTKALIDYENSNKALDKARLKSKDVKLA---------ETHQQECCQK-------FEQLSESAKEELINFKRKRVAAFRKNLIEMSELEI 384

[Close]

Query:  327 YKINTKTNRPSFLHQEITVRRRFSDFLGLHERLKLKYLFAGCIIPPAPEKNAFGNTKLKLSKEDQ-----TNSEFXXXXXXXXXXY--------------LQRIARHPLLVIDADFREFLEDDKELP-KAVNTQVLSGANMKKLFKNVGDAVGKITTKMDDCDQKDILWFDDKQVEMDNLDRHLSQIHCSFEHLISQRKELASQIKVFAQNCSQLSHVEEHNGLARALAQLXXXXXXXXXXXXRQAEVEFYTLLELLKDYLGMIGAVKEVLNERIRQYRVWQEAESNLNKKREQKARCEISGKVDKIPAFDLEIKECLNKVDRTREDFEKISKTIKTELEAFDTTKVIDFKEGIIKVLEAMI 1352
            + ++TKT   +F   E +V R+  DF+ LH+ L     +AG IIPPAP K  F   + K+ K  +     T  EF + ++     Y              LQR++ HP+L  D +F  FLE D++L  +  NT+ + G   K + K+  + +     ++DD       +F+ ++  + N    +       + +    K +A    +    C     +EE   + + L +++   E++  +E R +  E   L ELL+ Y+  I A K++L  R +    ++ +   L+K R +    +++         +   +EC  K       FE++S++ K EL  F   +V  F++ +I++ E  I
Sbjct:   47 FTVHTKTTLSTFQSPEFSVTRQHEDFVWLHDTLTETTDYAGLIIPPAPTKPDFDGPREKMQKLGEGEGSMTKEEFAKMKQELEAEYLAVFKKTVSTHEVFLQRLSSHPVLSKDRNFHVFLEYDQDLSVRRKNTKEMFGGFFKSVVKSADEVLFSGVKEVDD-------FFEQEKNFLINYYNRIKDSCAKADKMTRSHKNVADDY-IHTAACLHSLALEEPTVIKKYLLKVAELFEKLRKVEGRVSSDEDLKLTELLRYYMLNIEAAKDLLYRRTKALIDYENSNKALDKARLKSKDVKLA---------ETHQQECCQK-------FEQLSESAKEELINFKRKRVAAFRKNLIEMSELEI 384

[Close]

BLAST of Sorting nexin-2 vs. UniProt/SwissProt
Match: sp|Q9CWK8|SNX2_MOUSE (Sorting nexin-2 OS=Mus musculus OX=10090 GN=Snx2 PE=1 SV=2)

HSP 1 Score: 338.576 bits (867), Expect = 4.460e-109
Identity = 199/472 (42.16%), Postives = 289/472 (61.23%), Query Frame = 3

Query:   72 VSTMTDDD--DIFEEAMENTDEFGVQTEIRLDEP----TITRNASPPRTSVTEIS----------------NDRVPNQRKISKTGKF--IEISVSYPEKLGSGMAAYFIYKINTKTNRPSFLHQEITVRRRFSDFLGLHERLKLKYLFAGCIIPPAPEKNAFGNTKLKLSKEDQTNSEFXXXXXXXXXXYLQRIARHPLLVIDADFREFLEDDKELPKAVNTQVLSGANMKKLFKNVGDAVGKITTKMDDCDQKDILWFDDKQVEMDNLDRHLSQIHCSFEHLISQRKELASQIKVFAQNCSQLSHVEEHNGLARALAQLXXXXXXXXXXXXRQAEVEFYTLLELLKDYLGMIGAVKEVLNERIRQYRVWQEAESNLNKKREQKARCEISGKVDKIPAFDLEIKECLNKVDRTREDFEKISKTIKTELEAFDTTKVIDFKEGIIKVLEAMISSQEEIIHQWEKYIPDTAGIS 1415
            V  + DDD  D+F EA E         E+ LD P     ++   SP  T VT  +                 DR  ++ +    G    IEI VS PEK+G GM AY  Y++ TKT+   F   E +V+RRFSDFLGLH +L  KYL  G I+PPAPEK+  G TK+K+ KED +++EF+E+RRAALERYLQR  +HP L+ D D R+FLE   ELP+AVNTQ LSGA + ++     DAV K+T KM++ D     WF++KQ + +NLD+ L ++H S E L+  RKEL++    FA++ + L + E+H  L+RAL+QL+  +E+I  + + QA  +FY   ELL DY+ +I AVK V + R++ ++ W++A+  L KKRE +A+  ++ K DKI     EI+E   KV +   DFE+ISKTI+ E+  F+  +V DFK  IIK LE+++ +Q+++I  WE ++P+   I+
Sbjct:   62 VEVVLDDDREDLFAEATE---------EVSLDSPERELILSSEPSPAVTPVTPTTLIAPRIESKSISAPVIFDRSRDEIEEEANGDIFDIEIGVSDPEKVGDGMNAYMAYRVTTKTSLSMFSKSEFSVKRRFSDFLGLHSKLASKYLHVGYIVPPAPEKSIVGMTKVKVGKEDSSSTEFVEKRRAALERYLQRTVKHPTLLQDPDLRQFLESS-ELPRAVNTQALSGAGILRMVNKAADAVNKMTIKMNESDA----WFEEKQQQFENLDQQLRKLHASVEALVCHRKELSANTAAFAKSAAMLGNSEDHTALSRALSQLAEVEEKIDQLHQEQAFADFYMFSELLSDYIRLIAAVKGVFDHRMKCWQKWEDAQITLLKKRETEAKMMVANKPDKIQQAKNEIREWEAKVQQGERDFEQISKTIRKEVGRFEKERVKDFKAVIIKYLESLVQTQQQLIKYWEAFLPEAKAIA 519

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BLAST of Sorting nexin-2 vs. UniProt/SwissProt
Match: sp|O60749|SNX2_HUMAN (Sorting nexin-2 OS=Homo sapiens OX=9606 GN=SNX2 PE=1 SV=2)

HSP 1 Score: 337.806 bits (865), Expect = 9.672e-109
Identity = 197/465 (42.37%), Postives = 286/465 (61.51%), Query Frame = 3

Query:   87 DDDDIFEEAMENTDEFGVQTEIRLD----EPTITRNASPPRTSVTEIS----------------NDRVPNQRKISKTGKF--IEISVSYPEKLGSGMAAYFIYKINTKTNRPSFLHQEITVRRRFSDFLGLHERLKLKYLFAGCIIPPAPEKNAFGNTKLKLSKEDQTNSEFXXXXXXXXXXYLQRIARHPLLVIDADFREFLEDDKELPKAVNTQVLSGANMKKLFKNVGDAVGKITTKMDDCDQKDILWFDDKQVEMDNLDRHLSQIHCSFEHLISQRKELASQIKVFAQNCSQLSHVEEHNGLARALAQLXXXXXXXXXXXXRQAEVEFYTLLELLKDYLGMIGAVKEVLNERIRQYRVWQEAESNLNKKREQKARCEISGKVDKIPAFDLEIKECLNKVDRTREDFEKISKTIKTELEAFDTTKVIDFKEGIIKVLEAMISSQEEIIHQWEKYIPDTAGIS 1415
            D +D+F EA E         E+ LD    EP ++   SP  T VT  +                 DR   + +    G    IEI VS PEK+G GM AY  Y++ TKT+   F   E +V+RRFSDFLGLH +L  KYL  G I+PPAPEK+  G TK+K+ KED +++EF+E+RRAALERYLQR  +HP L+ D D R+FLE   ELP+AVNTQ LSGA + ++     DAV K+T KM++ D     WF++KQ + +NLD+ L ++H S E L+  RKEL++    FA++ + L + E+H  L+RAL+QL+  +E+I  + + QA  +FY   ELL DY+ +I AVK V + R++ ++ W++A+  L KKRE +A+  ++ K DKI     EI+E   KV +   DFE+ISKTI+ E+  F+  +V DFK  IIK LE+++ +Q+++I  WE ++P+   I+
Sbjct:   69 DREDLFAEATE---------EVSLDSPEREPILSSEPSPAVTPVTPTTLIAPRIESKSMSAPVIFDRSREEIEEEANGDIFDIEIGVSDPEKVGDGMNAYMAYRVTTKTSLSMFSKSEFSVKRRFSDFLGLHSKLASKYLHVGYIVPPAPEKSIVGMTKVKVGKEDSSSTEFVEKRRAALERYLQRTVKHPTLLQDPDLRQFLESS-ELPRAVNTQALSGAGILRMVNKAADAVNKMTIKMNESDA----WFEEKQQQFENLDQQLRKLHVSVEALVCHRKELSANTAAFAKSAAMLGNSEDHTALSRALSQLAEVEEKIDQLHQEQAFADFYMFSELLSDYIRLIAAVKGVFDHRMKCWQKWEDAQITLLKKREAEAKMMVANKPDKIQQAKNEIREWEAKVQQGERDFEQISKTIRKEVGRFEKERVKDFKTVIIKYLESLVQTQQQLIKYWEAFLPEAKAIA 519

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BLAST of Sorting nexin-2 vs. UniProt/SwissProt
Match: sp|Q5R9A9|SNX2_PONAB (Sorting nexin-2 OS=Pongo abelii OX=9601 GN=SNX2 PE=2 SV=1)

HSP 1 Score: 327.405 bits (838), Expect = 1.058e-104
Identity = 197/469 (42.00%), Postives = 286/469 (60.98%), Query Frame = 3

Query:   87 DDDDIFEEAMENTDEFGVQTEIRLD----EPTITRNASPPRTSVTEIS----------------NDRVPNQRKISKTGKF--IEISVSYPEKLGSGMAAYFIYKINTKTNRPSFLHQEITVRRRFSDFLGLHERLKLKYLFAGCIIPPAPEKNAFGNTKLKLSKEDQTNSEFXXXXXXXXXXYLQRIARHPLLVIDADFREFLEDDKELPKAVNTQVLSGANMKKLFKNVGDAVGKITTKMDDCDQKDILWFDDKQVEMDNLDRHLSQIHCSFEHLISQRKELASQIKVFAQNCSQLSHVEEHNGLARALAQLXXXXXXXXXXXXRQAEVEFYTLLELLKDYLGMIGAVKEVLNERIRQYRVWQEAESNLNKKREQKARCEISGKVDKIP----AFDLEIKECLNKVDRTREDFEKISKTIKTELEAFDTTKVIDFKEGIIKVLEAMISSQEEIIHQWEKYIPDTAGIS 1415
            D +D+F EA E         E+ LD    EP ++   SP  T VT  +                 DR   + +    G    IEI VS PEK+G GM AY  Y++ TKT+   F   E +V+RRFSDFLGLH +L  KYL  G I+PPAPEK+  G TK+K+ KED +++EF+E+RRAALERYLQR  +HP L+ D D R+FLE   ELP+AVNTQ LSGA + ++     DAV K+T KM++ D     WF++KQ + +NLD+ L ++H S E L+  RKEL++    FA++ + L + E+H  L+RAL+QL+  +E+I  + + QA  +FY   ELL DY+ +I AVK V + R++ ++ W++A+  L KKRE +A+  ++ K DKI         EI+E   KV +   DFE+ISKTI+ E+  F+  +V DFK  IIK LE+++ +Q+++I  WE ++P+   I+
Sbjct:   69 DREDLFAEATE---------EVSLDSPEREPILSSEPSPAVTPVTPTTLIAPRIESKSMSAPVIFDRSREEIEEEANGDIFDIEIGVSDPEKVGDGMNAYMAYRVTTKTSLSMFSKSEFSVKRRFSDFLGLHSKLASKYLHVGYIVPPAPEKSIVGMTKVKVGKEDSSSTEFVEKRRAALERYLQRTVKHPTLLQDPDLRQFLESS-ELPRAVNTQALSGAGILRMVNKAADAVNKMTIKMNESDA----WFEEKQQQFENLDQQLRKLHASVEALVCHRKELSANTAAFAKSAAMLGNSEDHTALSRALSQLAEVEEKIDQLHQEQAFADFYMFSELLSDYIRLIAAVKGVFDHRMKCWQKWEDAQITLLKKREAEAKMMVANKPDKIQQAKNEIREEIEEWEAKVQQGERDFEQISKTIRKEVGRFEKERVKDFKTVIIKYLESLVQTQQQLIKYWEAFLPEAKAIA 523

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BLAST of Sorting nexin-2 vs. UniProt/SwissProt
Match: sp|P0C220|SNX2_MACFA (Sorting nexin-2 OS=Macaca fascicularis OX=9541 GN=SNX2 PE=2 SV=1)

HSP 1 Score: 327.405 bits (838), Expect = 1.153e-104
Identity = 197/469 (42.00%), Postives = 286/469 (60.98%), Query Frame = 3

Query:   87 DDDDIFEEAMENTDEFGVQTEIRLD----EPTITRNASPPRTSVTEIS----------------NDRVPNQRKISKTGKF--IEISVSYPEKLGSGMAAYFIYKINTKTNRPSFLHQEITVRRRFSDFLGLHERLKLKYLFAGCIIPPAPEKNAFGNTKLKLSKEDQTNSEFXXXXXXXXXXYLQRIARHPLLVIDADFREFLEDDKELPKAVNTQVLSGANMKKLFKNVGDAVGKITTKMDDCDQKDILWFDDKQVEMDNLDRHLSQIHCSFEHLISQRKELASQIKVFAQNCSQLSHVEEHNGLARALAQLXXXXXXXXXXXXRQAEVEFYTLLELLKDYLGMIGAVKEVLNERIRQYRVWQEAESNLNKKREQKARCEISGKVDKIP----AFDLEIKECLNKVDRTREDFEKISKTIKTELEAFDTTKVIDFKEGIIKVLEAMISSQEEIIHQWEKYIPDTAGIS 1415
            D +D+F EA E         E+ LD    EP ++   SP  T VT  +                 DR   + +    G    IEI VS PEK+G GM AY  Y++ TKT+   F   E +V+RRFSDFLGLH +L  KYL  G I+PPAPEK+  G TK+K+ KED +++EF+E+RRAALERYLQR  +HP L+ D D R+FLE   ELP+AVNTQ LSGA + ++     DAV K+T KM++ D     WF++KQ + +NLD+ L ++H S E L+  RKEL++    FA++ + L + E+H  L+RAL+QL+  +E+I  + + QA  +FY   ELL DY+ +I AVK V + R++ ++ W++A+  L KKRE +A+  ++ K DKI         EI+E   KV +   DFE+ISKTI+ E+  F+  +V DFK  IIK LE+++ +Q+++I  WE ++P+   I+
Sbjct:   69 DREDLFAEATE---------EVSLDSPEREPILSSEPSPAVTPVTPTTLIAPRIESKSMSAPVIFDRSREEIEEEANGDIFDIEIGVSDPEKVGDGMNAYMAYRVTTKTSLSMFSKSEFSVKRRFSDFLGLHSKLASKYLHVGYIVPPAPEKSIVGMTKVKVGKEDSSSTEFVEKRRAALERYLQRTVKHPTLLQDPDLRQFLESS-ELPRAVNTQALSGAGILRMVNKAADAVNKMTIKMNESDA----WFEEKQQQFENLDQQLRKLHASVEALVCHRKELSANTAAFAKSAAMLGNSEDHTALSRALSQLAEVEEKIDQLHQEQAFADFYMFSELLSDYIRLIAAVKGVFDHRMKCWQKWEDAQITLLKKREAEAKMMVANKPDKIQQAKNEIREEIEEWEAKVQQGERDFEQISKTIRKEVGRFEKERVKDFKTVIIKYLESLVQTQQQLIKYWEAFLPEAKAIA 523

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BLAST of Sorting nexin-2 vs. UniProt/SwissProt
Match: sp|Q2TBW7|SNX2_BOVIN (Sorting nexin-2 OS=Bos taurus OX=9913 GN=SNX2 PE=2 SV=1)

HSP 1 Score: 327.02 bits (837), Expect = 1.479e-104
Identity = 196/465 (42.15%), Postives = 286/465 (61.51%), Query Frame = 3

Query:   87 DDDDIFEEAMENTDEFGVQTEIRLD----EPTITRNASPPRTSVTEIS----------------NDRVPNQRKISKTGKF--IEISVSYPEKLGSGMAAYFIYKINTKTNRPSFLHQEITVRRRFSDFLGLHERLKLKYLFAGCIIPPAPEKNAFGNTKLKLSKEDQTNSEFXXXXXXXXXXYLQRIARHPLLVIDADFREFLEDDKELPKAVNTQVLSGANMKKLFKNVGDAVGKITTKMDDCDQKDILWFDDKQVEMDNLDRHLSQIHCSFEHLISQRKELASQIKVFAQNCSQLSHVEEHNGLARALAQLXXXXXXXXXXXXRQAEVEFYTLLELLKDYLGMIGAVKEVLNERIRQYRVWQEAESNLNKKREQKARCEISGKVDKIPAFDLEIKECLNKVDRTREDFEKISKTIKTELEAFDTTKVIDFKEGIIKVLEAMISSQEEIIHQWEKYIPDTAGIS 1415
            D +D+F EA E         E+ LD    EP ++   SP  T VT  +                 DR  ++ +    G    IEI VS PEK+G GM AY  Y++ TKT+   F   E +V+RRFSDFLGLH +L  KYL  G I+PPAPEK+  G TK+K+ KED +++EF+E+RRAALERYLQR  +HP L+ D D R+FLE   ELP+AVNTQ LSGA + ++     DAV K+T KM++ D     WF++KQ + +N D+ L ++H S E L+  RKEL++    FA++ + L + E+H  L+RAL+QL+  +E+I  + + QA  +FY   ELL DY+ +I AVK V + R++ ++ W++A+  L KKRE +A+  ++ K DKI     EI+E   KV +   DFE+ISKTI+ E+  F+  +V DFK  IIK LE+++ +Q+++I  WE ++P+   I+
Sbjct:   69 DREDLFAEATE---------EVSLDSPEREPILSSETSPAVTPVTPTTLIAPRIESKSMSAPVIFDRSRDEIEEEANGDVFDIEIGVSDPEKVGDGMNAYMAYRVTTKTSLSMFSKSEFSVKRRFSDFLGLHSKLASKYLHVGYIVPPAPEKSIVGMTKVKVGKEDSSSTEFVEKRRAALERYLQRTVKHPTLLQDPDLRQFLESS-ELPRAVNTQALSGAGILRMVNKAADAVNKMTIKMNESDA----WFEEKQQQFENQDQQLRKLHASVEALVCHRKELSANTAAFAKSAAMLGNSEDHTALSRALSQLAEVEEKIDQLHQEQAFADFYMFSELLSDYIRLIAAVKGVFDHRVKCWQKWEDAQITLLKKRETEAKMMVANKPDKIQQAKNEIREWEAKVQQGERDFEQISKTIRKEVGRFEKERVKDFKTVIIKYLESLVQTQQQLIKYWEAFLPEAKAIA 519

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BLAST of Sorting nexin-2 vs. TrEMBL
Match: A0A1S3K472 (sorting nexin-2 OS=Lingula unguis OX=7574 GN=LOC106178690 PE=4 SV=1)

HSP 1 Score: 382.874 bits (982), Expect = 1.155e-123
Identity = 196/383 (51.17%), Postives = 276/383 (72.06%), Query Frame = 3

Query:  267 IEISVSYPEKLGSGMAAYFIYKINTKTNRPSFLHQEITVRRRFSDFLGLHERLKLKYLFAGCIIPPAPEKNAFGNTKLKLSKEDQTNSEFXXXXXXXXXXYLQRIARHPLLVIDADFREFLEDDKELPKAVNTQVLSGANMKKLFKNVGDAVGKITTKMDDCDQKDILWFDDKQVEMDNLDRHLSQIHCSFEHLISQRKELASQIKVFAQNCSQLSHVEEHNGLARALAQLXXXXXXXXXXXXRQAEVEFYTLLELLKDYLGMIGAVKEVLNERIRQYRVWQEAESNLNKKREQKARCEISGKVDKIPAFDLEIKECLNKVDRTREDFEKISKTIKTELEAFDTTKVIDFKEGIIKVLEAMISSQEEIIHQWEKYIPDTAGIS 1415
            +EISV  P K G GM++Y +Y +NTKT  P+F   + +V RRFSDFLGLH++L  K+L  G I+PPAPEK+  G TK+K+SKEDQ +SEF+E+RRAALERYL R A HP+L +D DFREFLE + +LPKA NT  LSGA + +LF  VGDAVGKIT KMD+ DQ    WF++KQ ++++LD HL ++H S E L+  RK+L+     FA++ + L++ EEH  L+RA++QL+  +E+I  + E QA+ +FY   ELLKDY+ +IGAVK+V N+R++ Y+ W+EAES LNKKRE K + E++ K DKIP    EI+E   KV++ +EDFEKIS+ I+ E+  FD  +V DFK  II  LE ++++Q+++I  WE ++P+   I+
Sbjct:  150 LEISVGNPHKKGDGMSSYMVYDVNTKTTIPAFQKSDFSVTRRFSDFLGLHDKLTEKHLMLGRIVPPAPEKSVIGMTKIKMSKEDQGSSEFVEKRRAALERYLNRTAAHPVLRMDPDFREFLELNGDLPKATNTSALSGAGVMRLFNKVGDAVGKITFKMDETDQ----WFEEKQQQVESLDTHLRKLHGSVEALVVHRKDLSQMTGSFAKSAAMLANAEEHTALSRAISQLAEIEEKIEQLHEDQADTDFYVFAELLKDYVTLIGAVKDVFNQRVKVYKAWKEAESMLNKKREAKVKLELAHKSDKIPQAQSEIEEWEGKVEKGQEDFEKISENIRKEVARFDKKRVRDFKITIINYLETLMNNQQQLIKYWETFLPEAKAIA 528

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BLAST of Sorting nexin-2 vs. TrEMBL
Match: A0A023FLQ8 (Putative membrane coat complex retromer subunit vps5/snx1 sorting nexin (Fragment) OS=Amblyomma cajennense OX=34607 PE=2 SV=1)

HSP 1 Score: 379.793 bits (974), Expect = 2.441e-123
Identity = 194/435 (44.60%), Postives = 293/435 (67.36%), Query Frame = 3

Query:  135 GVQTEIRLDEPTITRNASPPRTSVTEISND-------RVPNQRKISKTGKFIEISVSYPEKLGSGMAAYFIYKINTKTNRPSFLHQEITVRRRFSDFLGLHERLKLKYLFAGCIIPPAPEKNAFGNTKLKLSKEDQTNSE-FXXXXXXXXXXYLQRIARHPLLVIDADFREFLEDDKELPKAVNTQVLSGANMKKLFKNVGDAVGKITTKMDDCDQKDILWFDDKQVEMDNLDRHLSQIHCSFEHLISQRKELASQIKVFAQNCSQLSHVEEHNGLARALAQLXXXXXXXXXXXXRQAEVEFYTLLELLKDYLGMIGAVKEVLNERIRQYRVWQEAESNLNKKREQKARCEISGKVDKIPAFDLEIKECLNKVDRTREDFEKISKTIKTELEAFDTTKVIDFKEGIIKVLEAMISSQEEIIHQWEKYIPDTAGIS 1415
            G + E++   P      +PPR + T  S D       +   Q+K S+  +F+EISV  P+K+G GMAAY  Y++ T+TN P F   + +V RRFSDFLGLHE+L  K+L  G I+PPAPEK+  G TK+K+SK++Q  SE F+ERRRAALER+LQR A HP L +D DFREFLE + ELP+A NT  LSGA M +L   +GD+V KITTKMD+ D     WF++KQ ++DNLD  L ++H S E+++ QR+EL+     FA++ + L + EEH GL+RAL++L+   E +  ++ RQA  +FY L EL+KDYL ++GA+K+V ++R++ Y+ WQ A+  L +KRE KA+ E++ K DKIP    E+ E   KV+R +E+F+ +S+ I+TE++ F+  ++ DF+  +++  E ++ +Q+++I  WE ++P+   I+
Sbjct:   48 GAEDEVQRSNP----EPNPPRQATTLFSPDVSTLKPAKEKEQQKASEGEEFVEISVREPQKVGEGMAAYVTYRVVTRTNAPYFRKTQFSVNRRFSDFLGLHEKLVEKHLHMGRIVPPAPEKSVLGMTKIKMSKDEQVTSEDFVERRRAALERFLQRTAAHPSLKVDPDFREFLEQEAELPRATNTSSLSGAGMFRLISRMGDSVSKITTKMDEADP----WFEEKQQQIDNLDMQLKRLHASVENMVQQRRELSQSTGAFAKSAAMLGNCEEHTGLSRALSKLAEVGERVEQLQGRQANHDFYCLAELVKDYLALVGAIKDVFHQRVKVYQTWQHAQQMLARKREAKAKLELAAKSDKIPQARQEVLEWEAKVERGQEEFDNVSRVIRTEMDRFELNRITDFRNSVVRYFEFLLDTQQQLIKYWETFLPEAKAIA 474

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BLAST of Sorting nexin-2 vs. TrEMBL
Match: A0A131XK28 (Putative sorting nexin OS=Hyalomma excavatum OX=257692 PE=2 SV=1)

HSP 1 Score: 378.252 bits (970), Expect = 2.877e-122
Identity = 195/434 (44.93%), Postives = 293/434 (67.51%), Query Frame = 3

Query:  147 EIRLDEPTITRN---ASPPRTSVTEISND-------RVPNQRKISKTGKFIEISVSYPEKLGSGMAAYFIYKINTKTNRPSFLHQEITVRRRFSDFLGLHERLKLKYLFAGCIIPPAPEKNAFGNTKLKLSKEDQTNSE-FXXXXXXXXXXYLQRIARHPLLVIDADFREFLEDDKELPKAVNTQVLSGANMKKLFKNVGDAVGKITTKMDDCDQKDILWFDDKQVEMDNLDRHLSQIHCSFEHLISQRKELASQIKVFAQNCSQLSHVEEHNGLARALAQLXXXXXXXXXXXXRQAEVEFYTLLELLKDYLGMIGAVKEVLNERIRQYRVWQEAESNLNKKREQKARCEISGKVDKIPAFDLEIKECLNKVDRTREDFEKISKTIKTELEAFDTTKVIDFKEGIIKVLEAMISSQEEIIHQWEKYIPDTAGIS 1415
            E R  E  + RN    +PPR + T  S D       +   Q+K S+  +F+EISV  P+K+G GMAAY  Y++ T+TN P F   + +V RRFSDFLGLHE+L  K+L  G I+PPAPEK+  G TK+K+SK++Q  SE F+ERRRAALER+LQR A HP L +D DFREFLE + ELP+A NT  LSGA M +L   +GD+V KITTKMD+ D     WF++KQ ++DNLD  L ++H S E+++ QR+EL+     FA++ + L + EEH GL+RAL++L+   E +  ++ RQA  +FY L EL+KDYL ++GA+K+V ++R++ Y+ WQ A+  L +KRE KA+ E++ K +KIP    E+ E   KV+R +E+F+ +S+ I+TE++ F+  ++ DF+  +++  E ++ +Q+++I  WE ++P+   I+
Sbjct:   69 EFRATEDEVQRNNPEPNPPRQATTLFSPDASTLKPAKEKEQQKASEGEEFVEISVREPQKVGEGMAAYVTYRVVTRTNAPYFRKTQFSVNRRFSDFLGLHEKLVEKHLHMGRIVPPAPEKSVLGMTKIKMSKDEQVTSEDFVERRRAALERFLQRTAAHPSLRVDPDFREFLEQESELPRATNTSSLSGAGMFRLISRMGDSVSKITTKMDEADP----WFEEKQQQIDNLDIQLKRLHASVENMVQQRRELSQSTGAFAKSAAMLGNCEEHTGLSRALSKLAEVGERVEQLQGRQANHDFYCLAELVKDYLSLVGAIKDVFHQRVKVYQTWQHAQQMLARKREAKAKLELAAKSEKIPQARQEVLEWEAKVERGQEEFDNVSRVIRTEMDRFELNRIADFRNSVVRYFEFLLDTQQQLIKYWETFLPEAKAIA 498

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BLAST of Sorting nexin-2 vs. TrEMBL
Match: A0A023FZP4 (Putative membrane coat complex retromer subunit vps5/snx1 sorting nexin (Fragment) OS=Amblyomma parvum OX=251391 PE=2 SV=1)

HSP 1 Score: 375.555 bits (963), Expect = 1.237e-121
Identity = 193/435 (44.37%), Postives = 292/435 (67.13%), Query Frame = 3

Query:  135 GVQTEIRLDEPTITRNASPPRTSVTEISND-------RVPNQRKISKTGKFIEISVSYPEKLGSGMAAYFIYKINTKTNRPSFLHQEITVRRRFSDFLGLHERLKLKYLFAGCIIPPAPEKNAFGNTKLKLSKEDQTNSE-FXXXXXXXXXXYLQRIARHPLLVIDADFREFLEDDKELPKAVNTQVLSGANMKKLFKNVGDAVGKITTKMDDCDQKDILWFDDKQVEMDNLDRHLSQIHCSFEHLISQRKELASQIKVFAQNCSQLSHVEEHNGLARALAQLXXXXXXXXXXXXRQAEVEFYTLLELLKDYLGMIGAVKEVLNERIRQYRVWQEAESNLNKKREQKARCEISGKVDKIPAFDLEIKECLNKVDRTREDFEKISKTIKTELEAFDTTKVIDFKEGIIKVLEAMISSQEEIIHQWEKYIPDTAGIS 1415
            G + E++   P      + PR + T  S D       +   Q+K S+  +F+EISV  P+K+G GMAAY  Y++ T+TN P F   + +V RRFSDFLGLHE+L  K+L  G I+PPAPEK+  G TK+K+SK++Q  SE F+ERRRAALER+LQR A HP L +D DFREFLE + ELP+A NT  LSGA M +L   +GD+V KITTKMD+ D     WF++KQ ++DNLD  L ++H S E+++ QR+EL+     FA++ + L + EEH GL+RAL++L+   E +  ++ RQA  +FY L EL+KDYL ++GA+K+V ++R++ Y+ WQ A+  L +KRE KA+ E++ K DKIP    E+ E   KV+R +E+F+ +S+ I+TE++ F+  ++ DF+  +++  E ++ +Q+++I  WE ++P+   I+
Sbjct:   48 GAEDEVQRSNP----EPNSPRQATTLFSPDVSTLKPAKEKEQQKASEGEEFVEISVREPQKVGEGMAAYVTYRVVTRTNAPYFRKTQFSVNRRFSDFLGLHEKLVEKHLHMGRIVPPAPEKSVLGMTKIKMSKDEQVTSEDFVERRRAALERFLQRTAAHPSLKVDPDFREFLEQEAELPRATNTSSLSGAGMFRLISRMGDSVSKITTKMDEADP----WFEEKQQQIDNLDIQLKRLHASVENMVQQRRELSQSTGAFAKSAAMLGNCEEHTGLSRALSKLAEVGERVEQLQGRQANHDFYCLAELVKDYLALVGAIKDVFHQRVKVYQTWQHAQQMLARKREAKAKLELAAKSDKIPQARQEVLEWEAKVERGQEEFDNVSRVIRTEMDRFELNRITDFRNSVVRYFEFLLDTQQQLIKYWETFLPEAKAIA 474

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BLAST of Sorting nexin-2 vs. TrEMBL
Match: A0A131YSX6 (Sorting nexin-1/2 OS=Rhipicephalus appendiculatus OX=34631 PE=4 SV=1)

HSP 1 Score: 376.326 bits (965), Expect = 1.410e-121
Identity = 194/434 (44.70%), Postives = 293/434 (67.51%), Query Frame = 3

Query:  147 EIRLDEPTITRN---ASPPRTSVTEISND-------RVPNQRKISKTGKFIEISVSYPEKLGSGMAAYFIYKINTKTNRPSFLHQEITVRRRFSDFLGLHERLKLKYLFAGCIIPPAPEKNAFGNTKLKLSKEDQTNSE-FXXXXXXXXXXYLQRIARHPLLVIDADFREFLEDDKELPKAVNTQVLSGANMKKLFKNVGDAVGKITTKMDDCDQKDILWFDDKQVEMDNLDRHLSQIHCSFEHLISQRKELASQIKVFAQNCSQLSHVEEHNGLARALAQLXXXXXXXXXXXXRQAEVEFYTLLELLKDYLGMIGAVKEVLNERIRQYRVWQEAESNLNKKREQKARCEISGKVDKIPAFDLEIKECLNKVDRTREDFEKISKTIKTELEAFDTTKVIDFKEGIIKVLEAMISSQEEIIHQWEKYIPDTAGIS 1415
            E R  E  + R+    +PPR   T  S D       +   Q+K S+  +F+EISV  P+K+G GMAAY  Y++ T+TN P +   + +V RRFSDFLGLHE+L  K+L  G I+PPAPEK+  G TK+K+SK++Q  SE F+ERRRAALER+LQR A HP L +D DFREFLE + ELP+A NT  LSGA M +L   +GD+V KITTKMD+ D     WF++KQ ++DNLD  L ++H S E+++ QR+EL+     FA++ + L + EEH GL+RAL++L+   E +  ++ RQA  +FY L EL+KDYL ++GA+K+V ++R++ Y+ WQ A+  L +KRE KA+ E++ K +KIP    E+ E   KV+R +E+F+ +S+ I+TE++ F+ T++ DF+  +++  E ++ +Q+++I  WE ++P+   I+
Sbjct:   68 EFRATEDEVQRSNPEPNPPRQPTTLFSPDVSTLKPIKEKEQQKASEGEEFVEISVREPQKVGEGMAAYVTYRVVTRTNAPYYRKTQFSVNRRFSDFLGLHEKLVEKHLHMGRIVPPAPEKSVLGMTKIKMSKDEQVTSEDFVERRRAALERFLQRTAAHPSLRVDPDFREFLEQEAELPRATNTSSLSGAGMFRLISRMGDSVSKITTKMDEADP----WFEEKQQQIDNLDIQLKRLHASVENMVQQRRELSQSTGAFAKSAAMLGNCEEHTGLSRALSKLAEVGERVEQLQGRQANHDFYCLAELVKDYLSLVGAIKDVFHQRVKVYQTWQHAQQMLARKREAKAKLELAAKSEKIPQARQEVLEWEAKVERGQEEFDNVSRVIRTEMDRFELTRIADFRNSVVRYFEFLLDTQQQLIKYWETFLPEAKAIA 497

[Close]

BLAST of Sorting nexin-2 vs. Ensembl Cavefish
Match: snx1b (sorting nexin-1-like [Source:NCBI gene;Acc:103044300])

HSP 1 Score: 310.842 bits (795), Expect = 2.747e-99
Identity = 162/382 (42.41%), Postives = 256/382 (67.02%), Query Frame = 3

Query:  267 IEISVSYPEKLGSGMAAYFIYKINTKTNRPSFLHQEITVRRRFSDFLGLHERLKLKYLFAGCIIPPAPEKNAFGNTKLKLSKEDQTNSEFXXXXXXXXXXYLQRIARHPLLVIDADFREFLEDDKELPKAVNTQVLSGANMKKLFKNVGDAVGKITTKMDDCDQKDILWFDDKQVEMDNLDRHLSQIHCSFEHLISQRKELASQIKVFAQNCSQLSHVEEHNGLARALAQLXXXXXXXXXXXXRQAEVEFYTLLELLKDYLGMIGAVKEVLNERIRQYRVWQEAESNLNKKREQKARCEISGKVDKIPAFDLEIKECLNKVDRTREDFEKISKTIKTELEAFDTTKVIDFKEGIIKVLEAMISSQEEIIHQWEKYIPDTAGI 1412
            + I+V+ PEK+G GM AY  YK++T+T  P+F  +  +VRRRFSDFLGL+E+L +K+   GCIIPP P+K+  G TK+K+ KED +++EF+E+RRAALERYLQR+  HP L+ D+D +EFLE + ELP+AVNTQ LSG+   K+     DAV K+T KM++ D     WF+ K  E++N ++ L ++H S + L++ RKE+     +FA++ + L   EE++ L+RAL+QL+  ++++  + + QA  +F+ L ELL DY+ ++GAV+    +R++ ++ WQEA++ L KKRE +A+   + K DK+     ++ E   KV +   DFE+IS T++ E+  F+  K  DFK  I+K LE+++ SQ  ++  WE ++P+   I
Sbjct:  148 LNIAVTNPEKMGDGMNAYMTYKVSTQTTLPAFHIKTFSVRRRFSDFLGLYEKLSVKHHLMGCIIPPPPQKSVVGMTKVKVGKEDPSSAEFVEKRRAALERYLQRVVAHPALLQDSDVQEFLERE-ELPRAVNTQALSGSGFLKMINKASDAVNKMTIKMNESDN----WFESKLQEVENEEQLLRRLHASVDSLVNHRKEMCINTAMFAKSVAMLGSSEENSALSRALSQLAEVEDKLEQLHQEQAFSDFFILTELLADYVRLLGAVRGCFEQRMKAWQRWQEAQATLQKKREAEAKLLWANKPDKLQQAKEDLTEWEAKVGQCERDFERISSTLRKEVHRFEKEKCRDFKHHIVKYLESLLRSQHRVVKCWEAFLPEAKAI 524

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BLAST of Sorting nexin-2 vs. Ensembl Cavefish
Match: snx2 (sorting nexin 2 [Source:ZFIN;Acc:ZDB-GENE-051120-45])

HSP 1 Score: 307.375 bits (786), Expect = 3.292e-98
Identity = 187/445 (42.02%), Postives = 272/445 (61.12%), Query Frame = 3

Query:   87 DDDDIFEEAMENTDEFGVQTEIRLD----EPTITRNASPPRTSVTEI----------SNDRVPNQ-RKISKTGKF--IEISVSYPEKLGSGMAAYFIYKINTKTNRPSFLHQEITVRRRFSDFLGLHERLKLKYLFAGCIIPPAPEKNAFGNTKLKLSKEDQTNSEFXXXXXXXXXXYLQRIARHPLLVIDADFREFLEDDKELPKAVNTQVLSGANMKKLFKNVGDAVGKITTKMDDCDQKDILWFDDKQVEMDNLDRHLSQIHCSFEHLISQRKELASQIKVFAQNCSQLSHVEEHNGLARALAQLXXXXXXXXXXXXRQAEVEFYTLLELLKDYLGMIGAVKEVLNERIRQYRVWQEAESNLNKKREQKARCEISGKVDKIPAFDLEIKECLNKVDRTREDFEKISKTIKTELEAFDTTKVIDFKEGIIKVLEAMISSQEEI 1370
            D +D+F EA E         E+ LD    EP ++   SP  T VT              DR P++  +  + G    ++I VS PEK+G GM AY  YK+ TKT+   F   E TV+RRFSDFLGLH +L  KYL  G I+PPAPEK+  G TK+K+ KED +++EF+E+RR+ALERYL R   HP L+ D D  +FLE   ELP+AV+TQ LSGA + ++     +AV K+T KM++ D     WF++KQ + +NLD  L ++H S E L+  RKEL+     FA++ + L + E+H  L+RAL+QL+  +E+I  + + QA  +FY   ELL DY+ +I AVK V + R++ +  WQ+A+  L +KRE +A+ + + K DK+     EIKE   KV +   DFE+ISK I+ E+  F+  +V DFK  IIK LE+++ +Q+++
Sbjct:   70 DQEDLFAEATE---------EVSLDSPEREPILSDGPSPAITPVTPTVIITPRVDASMFDRSPDEDEEAEENGDTFDLQIMVSDPEKVGDGMNAYMAYKVTTKTSLNLFNRNEFTVKRRFSDFLGLHSKLASKYLHIGYIVPPAPEKSIVGMTKVKVGKEDLSSAEFVEKRRSALERYLMRTVNHPALLKDPDVIQFLES-TELPRAVSTQALSGAGILRMVNKAAEAVNKMTIKMNESDA----WFEEKQQQFENLDVQLRKLHASVESLVCHRKELSVNTASFAKSAAMLGNSEDHTALSRALSQLAEVEEKIDQLHQEQAYADFYLFSELLGDYVRLITAVKGVFDHRMKTWSKWQDAQVMLQRKREAEAKLQYANKPDKLQQAKEEIKEWEAKVQQGERDFEQISKNIRREVGRFEKQRVKDFKVVIIKYLESLVHTQQQV 500

[Close]

BLAST of Sorting nexin-2 vs. Ensembl Cavefish
Match: snx1b (sorting nexin-1-like [Source:NCBI gene;Acc:103044300])

HSP 1 Score: 296.59 bits (758), Expect = 5.510e-94
Identity = 163/392 (41.58%), Postives = 254/392 (64.80%), Query Frame = 3

Query:  267 IEISVSYPEKLGSGMAAYFIYKINTKTNRPSFLHQEITVRRRFSDFLGLHERLKLKYLFAGCIIPPAPEKNAFGNTKLKLSKEDQTNSEFXXXXXXXXXXYLQRIARHPLLVIDADFREFLEDDKELPKAVNTQVLSGANMKKLFKNVGDAVGKITTKMDDCDQKDILWFDDKQVEMDNLDRHLSQIHCSFEHLISQRKELASQIKVFAQNCSQLSHVEEHNGLARALAQLXXXXXXXXXXXXRQAEVEFYTLLELLKDYLGMIGAVKEVLNERIR----------QYRVWQEAESNLNKKREQKARCEISGKVDKIPAFDLEIKECLNKVDRTREDFEKISKTIKTELEAFDTTKVIDFKEGIIKVLEAMISSQEEIIHQWEKYIPDTAGI 1412
            + I+V+ PEK+G GM AY  YK++T+T  P+F  +  +VRRRFSDFLGL+E+L +K+   GCIIPP P+K+  G TK+K+ KED +++EF+E+RRAALERYLQR+  HP L+ D+D +EFLE + ELP+AVNTQ LSG+   K+     DAV K+T KM++ D     WF+ K  E++N ++ L ++H S + L++ RKE+     +FA++ + L   EE++ L+RAL+QL+  ++++  + + QA  +F+ L ELL DY+ ++GAV+ V N               ++ WQEA++ L KKRE +A+   + K DK+     ++ E   KV +   DFE+IS T++ E+  F+  K  DFK  I+K LE+++ SQ  ++  WE ++P+   I
Sbjct:  121 LNIAVTNPEKMGDGMNAYMTYKVSTQTTLPAFHIKTFSVRRRFSDFLGLYEKLSVKHHLMGCIIPPPPQKSVVGMTKVKVGKEDPSSAEFVEKRRAALERYLQRVVAHPALLQDSDVQEFLERE-ELPRAVNTQALSGSGFLKMINKASDAVNKMTIKMNESDN----WFESKLQEVENEEQLLRRLHASVDSLVNHRKEMCINTAMFAKSVAMLGSSEENSALSRALSQLAEVEDKLEQLHQEQAFSDFFILTELLADYVRLLGAVR-VRNSLFYGTLLKYTFCCSWQRWQEAQATLQKKREAEAKLLWANKPDKLQQAKEDLTEWEAKVGQCERDFERISSTLRKEVHRFEKEKCRDFKHHIVKYLESLLRSQHRVVKCWEAFLPEAKAI 506

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BLAST of Sorting nexin-2 vs. Ensembl Cavefish
Match: snx2 (sorting nexin 2 [Source:ZFIN;Acc:ZDB-GENE-051120-45])

HSP 1 Score: 293.508 bits (750), Expect = 1.042e-92
Identity = 186/449 (41.43%), Postives = 272/449 (60.58%), Query Frame = 3

Query:   87 DDDDIFEEAMENTDEFGVQTEIRLD----EPTITRNASPPRTSVTEI----------SNDRVPNQ-RKISKTGKF--IEISVSYPEKLGSGMAAYFIYKINTKTNRPSFLHQEITVRRRFSDFLGLHERLKLKYLFAGCIIPPAPEKNAFGNTKLKLSKEDQTNSEFXXXXXXXXXXYLQRIARHPLLVIDADFREFLEDDKELPKAVNTQVLSGANMKKLFKNVGDAVGKITTKMDDCDQKDILWFDDKQVEMDNLDRHLSQIHCSFEHLISQRKELASQIKVFAQNCSQLSHVEEHNGLARALAQLXXXXXXXXXXXXRQAEVEFYTLLELLKDYLGMIGAVKEVLNERIRQYRVWQEAESNLNKKREQKARCEISGKVDKI----PAFDLEIKECLNKVDRTREDFEKISKTIKTELEAFDTTKVIDFKEGIIKVLEAMISSQEEI 1370
            D +D+F EA E         E+ LD    EP ++   SP  T VT              DR P++  +  + G    ++I VS PEK+G GM AY  YK+ TKT+   F   E TV+RRFSDFLGLH +L  KYL  G I+PPAPEK+  G TK+K+ KED +++EF+E+RR+ALERYL R   HP L+ D D  +FLE   ELP+AV+TQ LSGA + ++     +AV K+T KM++ D     WF++KQ + +NLD  L ++H S E L+  RKEL+     FA++ + L + E+H  L+RAL+QL+  +E+I  + + QA  +FY   ELL DY+ +I AVK V + R++ +  WQ+A+  L +KRE +A+ + + K DK+         EI+E   KV +   DFE+ISK I+ E+  F+  +V DFK  IIK LE+++ +Q+++
Sbjct:   70 DQEDLFAEATE---------EVSLDSPEREPILSDGPSPAITPVTPTVIITPRVDASMFDRSPDEDEEAEENGDTFDLQIMVSDPEKVGDGMNAYMAYKVTTKTSLNLFNRNEFTVKRRFSDFLGLHSKLASKYLHIGYIVPPAPEKSIVGMTKVKVGKEDLSSAEFVEKRRSALERYLMRTVNHPALLKDPDVIQFLE-STELPRAVSTQALSGAGILRMVNKAAEAVNKMTIKMNESDA----WFEEKQQQFENLDVQLRKLHASVESLVCHRKELSVNTASFAKSAAMLGNSEDHTALSRALSQLAEVEEKIDQLHQEQAYADFYLFSELLGDYVRLITAVKGVFDHRMKTWSKWQDAQVMLQRKREAEAKLQYANKPDKLQQAKEEIKEEIEEWEAKVQQGERDFEQISKNIRREVGRFEKQRVKDFKVVIIKYLESLVHTQQQV 504

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BLAST of Sorting nexin-2 vs. Ensembl Cavefish
Match: snx1a (sorting nexin 1a [Source:ZFIN;Acc:ZDB-GENE-060302-3])

HSP 1 Score: 273.092 bits (697), Expect = 2.039e-83
Identity = 155/383 (40.47%), Postives = 244/383 (63.71%), Query Frame = 3

Query:  267 IEISVSYPEKLGSGMAAYFIYKINTKTNRPSFLHQEITVRRRFSDFLGLHERLKLKYLFAGCIIPPAPEKNAFGNTKLKLSKEDQTNSEFXXXXXXXXXXYLQRIARHPLLVIDADFREFLEDDKELPKAVNTQVLSGANMKKLFKNVGDAVGKITTKMDDCDQKDILWFDDKQVEMDNLDRHLSQIHCSFEHLISQRKELASQIKVFAQNCSQLSHVEEHNGLARALAQLXXXXXXXXXXXXRQAEVEFYTLLELLKDYLGMIGAVKEVLNERIRQYRVWQEAESNLNKKREQKARCEISGKVDKIPAFDLEIKECLNKVDRTREDFEKISKTIKTELEAFDTTKVIDFKEGIIKVLEAMISSQEEIIHQWEKYIPDTAGIS 1415
            + ISV+ PEK+G        +     T    F  ++  VRRRFSDFLGL+E+L  K+   G I+PP PEK+  G TK+K+ KED +++EF+ERRRAALERYLQR+  HP L+ D D REFLE + ELP+AV TQ LSGA   K+     DAV K+T KM++ D    +WF++K  E+++ D+ L ++H   + L+  RKEL+    +FA++ + L   E++  L+RAL+QL+  ++ I  + + QA  +F+   ELL DY+ ++GAV+   ++R++ ++ WQ+A++ L KKRE +A+   + K DK+     EI E   KV +   DFE++S T++ E+  ++  K  DFK+ II+ LE+++ SQ+++I  WE ++P+   I+
Sbjct:  278 LNISVTNPEKVGK-------FTPTPITTLSMFRSKQFVVRRRFSDFLGLYEKLSEKHAQNGYIVPPPPEKSILGMTKVKVGKEDPSSAEFVERRRAALERYLQRVVCHPSLLQDPDVREFLEKE-ELPRAVGTQALSGAGFLKMINKATDAVSKMTIKMNESD----VWFEEKLQEVESEDQQLRKLHAMVDSLVIHRKELSMNTAMFAKSVAMLGSSEDNTALSRALSQLAEVEDRIEQLHQDQASNDFFIFAELLADYIRLLGAVRACFDQRMKAWQRWQDAQNMLQKKRETEAKLLWANKPDKLQQAKDEIVEWEAKVSQYERDFERVSATVRKEVIRYEKEKTRDFKKQIIRYLESLLQSQQQLIKYWEAFLPEAKAIA 648

[Close]

BLAST of Sorting nexin-2 vs. Ensembl Sea Lamprey
Match: snx1a (sorting nexin 1a [Source:ZFIN;Acc:ZDB-GENE-060302-3])

HSP 1 Score: 326.25 bits (835), Expect = 1.159e-105
Identity = 166/383 (43.34%), Postives = 267/383 (69.71%), Query Frame = 3

Query:  267 IEISVSYPEKLGSGMAAYFIYKINTKTNRPSFLHQEITVRRRFSDFLGLHERLKLKYLFAGCIIPPAPEKNAFGNTKLKLSKEDQTNSEFXXXXXXXXXXYLQRIARHPLLVIDADFREFLEDDKELPKAVNTQVLSGANMKKLFKNVGDAVGKITTKMDDCDQKDILWFDDKQVEMDNLDRHLSQIHCSFEHLISQRKELASQIKVFAQNCSQLSHVEEHNGLARALAQLXXXXXXXXXXXXRQAEVEFYTLLELLKDYLGMIGAVKEVLNERIRQYRVWQEAESNLNKKREQKARCEISGKVDKIPAFDLEIKECLNKVDRTREDFEKISKTIKTELEAFDTTKVIDFKEGIIKVLEAMISSQEEIIHQWEKYIPDTAGIS 1415
            + I+++ PEK+G GM AY  Y + T T+ P F  +E TV+RRFSDFLGL+E+L  K+  +G I+PPAPEK+  G TK+K+ K+D ++ EF+ERRRAALERYLQR ++HP L+ D DFR+FLE D ELP+AVNTQ LSGA + ++     DAV K+T KM++ D     WF++KQ+E +NL+  L ++H +FE L++ RKE++     FA++ + L + E++  L+RAL+QL+  +E+I A+ + QA  + Y   ELL DY+ ++ +++ V ++R + ++ WQ+A++NL+KKRE +A+ + + K DK+     EI+E   KV +   +FE +SKTI+ E+  F+  +V DFK GI++ +E++I++++++I  WE ++P+   I+
Sbjct:  169 LRITITNPEKVGDGMNAYMAYNVTTTTSLPMFKRKEFTVKRRFSDFLGLYEKLTEKFSHSGFIVPPAPEKSVLGMTKVKVGKDDPSSVEFVERRRAALERYLQRTSKHPTLMQDPDFRDFLERD-ELPRAVNTQALSGAGILRMVTKAADAVNKMTIKMNESDS----WFEEKQLEFENLETQLRKLHGNFEGLVNHRKEMSLNTAAFAKSAAMLGNSEDNTALSRALSQLAEVEEKIDALHQEQANADLYVFAELLADYIRLLTSIRGVFDQRAKSWQRWQDAQANLHKKRENEAKLQWANKPDKLQQAKDEIREWDAKVQQGESEFEIVSKTIRKEVMRFEKERVRDFKNGIVRYIESLINTEQQLIKYWEAFLPEAKAIA 546

[Close]

BLAST of Sorting nexin-2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000227.1 (pep scaffold:Pmarinus_7.0:GL480786:1217:16989:1 gene:ENSPMAG00000000197.1 transcript:ENSPMAT00000000227.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 72.4034 bits (176), Expect = 6.597e-14
Identity = 84/367 (22.89%), Postives = 155/367 (42.23%), Query Frame = 3

Query:  324 IYKINTKTNRPSFLHQEITVRRRFSDFLGLHERLKLKYLFAGCIIPPAPEKNAFGNTKLKLSKEDQ-----TNSEFXXXXXXXXXXY--------------LQRIARHPLLVIDADFREFLEDDKEL-PKAVNTQVLSGANMKKLFKNVGDAVGKITTKMDD-CDQKDILWFD------DKQVEMDNLDRHLSQIHCSFEHLISQRKELASQIKVFAQNCSQLSHVEEHNGLARALAQLXXXXXXXXXXXXRQAEVEFYTLLELLKDYLGMIGAVKEVLNERIRQYRVWQEAESNLNKKREQKARCEISGKVDKIPAFDLEIKECLNKVDRTREDFEKISKTIKTELEAFDTTKVIDFKEGIIKVLE 1343
            ++ + TKT  P+F + ++ V R+  DF+ LH+       +AG IIPPAP +  F  ++ KL +  Q     T  EF   ++     Y              L R+A HP+L  D++ + FLE   EL  +  N + + G   + + K+  + V      +D+  + + +   D      D   + D + +    I   + H+ +    LA+Q               +   L++    ++   E+   +E R A  +   L +L + Y+    A K++L  R R    ++ A   L++ R +                D+   E   +    R  FEK+S T K EL+ F   +V+ F++G++++ E
Sbjct:   46 LFTVCTKTILPAFKNSKVCVSRQHEDFVWLHDSYVENGTYAGFIIPPAPLRPDFSASRDKLHRLGQSEGTMTKEEFSRMKQEVEAEYLVVFKKTVAMHEGFLVRLATHPVLSQDSNLQVFLEYTHELNVRGKNKKEMLGGFFRNVVKSADELVVSGVEDIDEFMEHEKVFLVDYHLRIKDATTKADKMTKAHKNIAEDYLHISASFTSLATQ---------------DSRNLSKLYLCIADVLEKTRKLEGRAASDQDLKLSDLFRYYMKDSQAAKDLLYRRTRALVDYENANKALDRARTRNK--------------DVAATESQQQTSLQR--FEKLSSTGKQELKDFRCRRVLAFRKGLVELTE 381

[Close]

BLAST of Sorting nexin-2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000009855.1 (pep scaffold:Pmarinus_7.0:GL476399:593532:610067:1 gene:ENSPMAG00000008881.1 transcript:ENSPMAT00000009855.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 66.6254 bits (161), Expect = 4.261e-12
Identity = 78/362 (21.55%), Postives = 159/362 (43.92%), Query Frame = 3

Query:  327 YKINTKTNRPSFLHQEITVRRRFSDFLGLHERLKLKYLFAGCIIPPAPEKNAFGNTKLKLSKEDQ-----TNSEFXXXXXXXXXXYLQ--------------RIARHPLLVIDADFREFLEDDKELP-KAVNTQVLSGANMKKLFKNVGDAVGKITTKMDDCDQKDILWFDDKQVEMDNLDRHLSQIHCSFEHLISQRKELASQ---IKVFAQNCSQLSHVEEHNGLARALAQLXXXXXXXXXXXXRQAEVEFYTLLELLKDYLGMIGAVKEVLNERIRQYRVWQEAESNLNKKREQKARCEISGKVDKIPAFDLEIKECLNKVDRTREDFEKISKTIKTELEAFDTTKVIDFKEGIIKVLE 1343
            + + T T+ P+F   +++V R+  +F+ LH+       + G +IPPAP +  F +++ KL +  +     T  EF + ++     YL               R+A HP+L  D +F  FLE D+EL  +  NT+ + G  +K + K+  +    + +   D D+    +F+ +++ +      + +     + +    K ++     I  +  N  +    +E++ L+R L   S   E+    + R A  +   L +LL+ Y+    A K++L  R R     +     L+K R          K   +   +++ K  ++K       F+ +S + + EL  F   +V  F++ ++++ E
Sbjct:   49 FTVQTTTSLPTFKKGKLSVSRQHEEFIWLHDSYVENEDYGGIVIPPAPPRPDFDSSREKLQRLGEGEATMTKEEFSKMKQELEAEYLAIFKKTVAMHEVFLCRLAAHPILSQDRNFHIFLEYDQELSVRGKNTKEILGGFLKSMMKSADEV---LVSGAKDSDE----FFEHEKIFLLEYHMRVKESALKADKMTRAHKNVSEDYIGISTWLYNIGE----QEYSKLSRFLQLSSDMFEKYRKQQGRVASDQDLKLTDLLRYYVRETQAAKDLLYRRARSLVDAENTGRALDKAR---------AKGKDVQQAEMQQKLAMHK-------FDSLSTSARQELMDFKMRRVAAFRKNLVEMAE 383

[Close]

BLAST of Sorting nexin-2 vs. Ensembl Sea Lamprey
Match: snx30 (sorting nexin family member 30 [Source:NCBI gene;Acc:550496])

HSP 1 Score: 61.2326 bits (147), Expect = 1.951e-10
Identity = 41/119 (34.45%), Postives = 58/119 (48.74%), Query Frame = 3

Query:  273 ISVSYPEKLGSGMAAYFIYKINTKTNRPSFLHQEITVRRRFSDFLGLHERLKLKYLFAGCIIPPAPEKNAFGNTKLKLSKEDQTNSEFXXXXXXXXXXYLQRIARHPLLVIDADFREFL 629
            + V  PEK  + M  Y  Y++  +T R  +   E  VRRR+ DF  L  R KL+      IIPP PEK             D+   +F+  R+ AL+++L R+A HP L   + F  FL
Sbjct:   28 VRVDSPEKHVTAMETYITYRVTVRTTRSEYDGMEFVVRRRYQDFDWL--RTKLEETQPTHIIPPLPEKFVMKGVV------DRFTEDFVTTRQKALDKFLNRLANHPTLSFSSYFHSFL 138

[Close]

BLAST of Sorting nexin-2 vs. Ensembl Sea Lamprey
Match: snx6 (sorting nexin 6 [Source:ZFIN;Acc:ZDB-GENE-050913-152])

HSP 1 Score: 60.8474 bits (146), Expect = 2.783e-10
Identity = 89/362 (24.59%), Postives = 157/362 (43.37%), Query Frame = 3

Query:  327 YKINTKTNRPSFLHQEITVRRRFSDFLGLHERLKLKYLFAGCIIPPAPEKNAFGNTKLKLSKEDQ-----TNSEFXXXXXXXXXXYLQ--------------RIARHPLLVIDADFREFLEDDKELP-KAVNTQVLSGANMKKLFKNVGDAVGKITTKMDDCDQKDILWFDDKQVEMDNLDRHLSQIHCSFEHLISQRKELASQIKVFAQNCSQLSHVEEHNGLARALAQLXXXXXXXXXXXXRQAEVEFYTLLELLKDYLGMIGAVKEVLNERIRQYRVWQEAESNLNKKREQKARCEISGKVDKIPAFDLEIKECLNKVDRTREDFEKISKTIKTELEAFDTTKVIDFKEGIIKVLEAMI 1352
            + ++TKT  P F   E +V R+  +F+ LH+  +    +AG IIPPAP +  F  ++ KL K  +     T  EF + ++     YL               R+A HPLL  D +F  FLE D++L  +  N +   G  +K + K   + +   T  +D+       +FD ++  +      +       + +    K +A      +     L   +E   L+R   + +   E+   +E R A  E   L +LL+ Y+    A K++L  R R    ++ A   L+K R +    + +    +I         C +K       FEK+S++ K EL  F T +V+ F++ ++++ E  I
Sbjct:   51 FTVHTKTTLPYFKQGEFSVVRQHEEFIWLHDAYEENEEYAGIIIPPAPPRPDFDASREKLQKLGEGEGTMTKEEFTKMKQELEAEYLAIFKKTVAMHEVFLCRLAAHPLLRKDHNFHVFLEYDQDLSVRGKNKKEKFGGFLKNMVKTADEVLIAGTKDVDE-------FFDHEKTFILEYHGRIKDATMKADKMTRAHKNVAEDYIRISSGVYTLG-TQEPTNLSRIFLKFTELLEKTRKLEGRVASDEDLKLSDLLRYYMKDSQAAKDLLYRRARSLIDYENANKALDKARAKNKDVQQAEAHQQI---------CCHK-------FEKLSESAKHELIDFKTRRVVAFRKNLVEMTEMEI 388

[Close]

BLAST of Sorting nexin-2 vs. Ensembl Yeast
Match: VPS5 (Nexin-1 homolog; required for localizing membrane proteins from a prevacuolar/late endosomal compartment back to late Golgi; structural component of retromer membrane coat complex; forms a retromer subcomplex with Vps17p; required for recruiting the retromer complex to the endosome membranes; VPS5 has a paralog, YKR078W, that arose from the whole genome duplication [Source:SGD;Acc:S000005595])

HSP 1 Score: 89.7373 bits (221), Expect = 2.508e-19
Identity = 102/428 (23.83%), Postives = 194/428 (45.33%), Query Frame = 3

Query:  207 TEISNDRVPNQRKISKTGKFIEISVSYPEKLGSGMAAYFIYKINTKTNRPSFLHQEITVRRRFSDFLGLHERLKLKYLFAGCIIPPAPEKNAFGNTKLKLSKEDQTNSEFXXXXXXXXXXYLQRIARHPLLVIDADFREFLEDD---KELPK--------AVN------------TQVLSGANMKKLFKNVG-DAVG---------KITTKMDDCDQKDILWFDDKQVEMDNLDRHLSQIHCSFEHLISQRKELASQIKVFAQNCSQLSHVEEHNGLARALAQLXXXXXXXXXXXXRQAEVEFYTLLELLKDYLGMIGAVKEVLNERIRQYRVWQEAESNLNKKREQKARCEISGKVDKIPAFDLEIKECLNKVDRTREDFEKISKTIKTELEAFDTTKVIDFKEGIIKVLEAMISSQEEIIHQWEKY 1391
            T+I +   P ++ ++      ++ V  P K+G   + +  Y + ++++     + +++  RR+ DF  L+ +L+  +   G +IPP PEK + G+ K            F+E RR  +E  L++I + P+L  D DF  FL  D    E  K        A+N             Q+L   +  ++ KN G DA               K ++ D+    +F +K+ ++D L+ +L ++  S E + + R  LA+  + F+     L+ +      +  L   +   + I +  ER +  E  T+  +L DY+  + +VK + N+R +        E+++NKK  Q  +   +   +K      E +    + + T++ ++ +   IK E + F T K+ +F+ G+   LEA I SQ+E I  WE +
Sbjct:  266 TKIGSKVPPTEKAVA-----FKVEVKDPVKVGELTSIHVEYTVISESSLLELKYAQVS--RRYRDFRWLYRQLQNNHW--GKVIPPPPEKQSVGSFK----------ENFIENRRFQMESMLKKICQDPVLQKDKDFLLFLTSDDFSSESKKRAFLTGSGAINDSNDLSEVRISEIQLLGAEDAAEVLKNGGIDAESHKGFMSISFSSLPKYNEADE----FFIEKKQKIDELEDNLKKLSKSLEMVDTSRNTLAASTEEFSSMVETLASLNVSEPNSELLNNFADVHKSIKSSLERSSLQETLTMGVMLDDYIRSLASVKAIFNQRSKLGYFLVVIENDMNKKHSQLGKLGQNIHSEKFREMRKEFQTLERRYNLTKKQWQAVGDKIKDEFQGFSTDKIREFRNGMEISLEAAIESQKECIELWETF 670

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BLAST of Sorting nexin-2 vs. Ensembl Yeast
Match: SNX4 (Sorting nexin; involved in retrieval of late-Golgi SNAREs from post-Golgi endosomes to the trans-Golgi network and in cytoplasm to vacuole transport; contains a PX phosphoinositide-binding domain; forms complexes with Snx41p and with Atg20p [Source:SGD;Acc:S000003573])

HSP 1 Score: 58.5362 bits (140), Expect = 1.258e-9
Identity = 98/413 (23.73%), Postives = 178/413 (43.10%), Query Frame = 3

Query:  264 FIEISVSYPEKL----GSGMAAYFIYKINTKTNRPSFLHQE------ITVRRRFSDFLGLHERLKLKYLFAGCIIPPAPEKNAFGNTKLKLSKEDQTNSEFXXXXXXXXXXYLQRIARHPLLVIDADFREFL-EDDKELPKAV-------NTQVLSGANMKKLFKNV-------------GDAVGKITTKMDDCDQKDILWFDDKQVEMDNLDRHLSQIHCSFEHLISQRKELASQIKVFAQNCSQLSHVEEHNGLARALAQLXXXXXXXXXXXXRQAEVEFYTLLELLK-------DYLGMIGAVKEVLNERIRQYRVWQEAESNLNKKREQKARCEISGKVDKIPAFDLEIKECLNKVDRTREDFEKISKTIKTELEAFDTTKVIDFKEGIIKVLEAMISSQEEIIHQWEK 1388
            + EI VS P+K     GS  + Y  Y+I+TKTN  SF          I V RR+SD L LH+ L  +  F  CIIPP P+K  F     +    D+ +  F ++R  +L+ +L+R++ HP L     F+ FL   D E  + V       N   ++ A M   FK V              D + +  TK+D    K +   D    +   L  +L ++    E +  + +ELA+++K+F +  +QLS+          L  L+   +    ++ +  E    ++ +L+K       DY  +   +   + E+      +  +    NK  E     + + + +KI   + +I     +++  ++  +   +    E++ F++ K  + K+ +  + +  I   E I+  WEK
Sbjct:   27 WFEIIVSDPQKRTGDPGSS-SGYVSYQISTKTNNTSFYDNRGDPESIIVVHRRYSDLLLLHDILLNR--FPTCIIPPLPDKKVF-----QYIAGDRFSQRFTQKRCHSLQNFLRRVSLHPDLSQSKVFKTFLVSKDWESHRKVLQDSLQPNKDEVTDAFM-NAFKTVHKQNEEFTEIREKSDKLDRTVTKIDKLFHKVVKKNDSMSEDYTKLGSNLQELQ---ELVTGENEELAAKLKIFNEGVTQLSY---------GLQDLTKYLDYEYIVDLKDLEHYIDSMRQLIKLKDQKQIDYEELSDYLTRSIKEKNNLISGYGGSNFFANKLEELAGINQEASRREKINKLEGKITSLTGELENAKKVADGFEQECLKEIDHFESVKTAEIKKSLGSLADHHIEFYERILEAWEK 418

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BLAST of Sorting nexin-2 vs. Ensembl Nematostella
Match: EDO32102 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SW17])

HSP 1 Score: 353.984 bits (907), Expect = 3.777e-118
Identity = 182/383 (47.52%), Postives = 263/383 (68.67%), Query Frame = 3

Query:  267 IEISVSYPEKLGSGMAAYFIYKINTKTNRPSFLHQEITVRRRFSDFLGLHERLKLKYLFAGCIIPPAPEKNAFGNTKLKLSKEDQTNSEFXXXXXXXXXXYLQRIARHPLLVIDADFREFLEDDKELPKAVNTQVLSGANMKKLFKNVGDAVGKITTKMDDCDQKDILWFDDKQVEMDNLDRHLSQIHCSFEHLISQRKELASQIKVFAQNCSQLSHVEEHNGLARALAQLXXXXXXXXXXXXRQAEVEFYTLLELLKDYLGMIGAVKEVLNERIRQYRVWQEAESNLNKKREQKARCEISGKVDKIPAFDLEIKECLNKVDRTREDFEKISKTIKTELEAFDTTKVIDFKEGIIKVLEAMISSQEEIIHQWEKYIPDTAGIS 1415
            +EI V+ PEK+G GM A+  Y++ TKT+ P F   E TV+RRFSDFLGLHER+  KYL  G I+PPAPEK+  G +K+K SKED  +++F+ +RRA LER+L R+A HP L  D DFR+FLE D ELP+A +T  LSG  +K+L K++GD +  +TTKM + DQ    WF++KQ +++ LD+ L ++H + E L+  RKEL+     FA++ + LS+ EEH  L+RAL QL+  +E+I A+   Q+E +F+   ELLKDY+G+I +VK    ER+R Y VWQ A+  L KKRE   + E++GK +K+P    E+KE   KV++ +EDFE ISK I+ E+  F+  +V DF+  IIK LEAM+ +Q+++I QWE ++P+   I+
Sbjct:   14 MEIKVTDPEKVGDGMNAFMSYRVITKTSMPEFNSPETTVKRRFSDFLGLHERINAKYLHLGRIVPPAPEKSVIGMSKVKFSKEDSNSTDFIGKRRAVLERFLNRVAAHPELRKDPDFRQFLEAD-ELPRAKDTAALSGGGLKRLVKSMGDTMFSLTTKMSESDQ----WFEEKQQQIETLDQQLKKLHHNVEILVMHRKELSISTASFAKSAAMLSNAEEHTSLSRALTQLAEVEEKIEALHVEQSETDFFVFSELLKDYIGLISSVKACFQERVRAYSVWQHAQQTLTKKREALVKTELAGKNEKLPQAQEEVKEWEQKVEKGQEDFEAISKMIRKEMVRFENNRVKDFRAAIIKYLEAMMDTQQQLIKQWEGFLPEAKAIA 391

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BLAST of Sorting nexin-2 vs. Ensembl Nematostella
Match: EDO46895 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RNQ3])

HSP 1 Score: 68.1662 bits (165), Expect = 2.234e-12
Identity = 51/130 (39.23%), Postives = 70/130 (53.85%), Query Frame = 3

Query:  243 KISKTG-KFIEISVSYPEKLGSGMAAYFIYKINTKTNRPSFLHQEITVRRRFSDFLGLHERLKLKYLFAGCIIPPAPEKNAFGNTKLKLSKEDQTNSEFXXXXXXXXXXYLQRIARHPLLVIDADFREFL 629
            K+S T  K + I V  PEK   G   Y  Y + TKT R  F H E +VRRR+ DFL L +R++  Y     IIPP PEK++F          D+ + EFL+ R  AL +++ RIA HP++  +     FL
Sbjct:   18 KMSATHVKDLFIRVDDPEKHVGG---YVSYNVITKTTRNQFDHPEYSVRRRYQDFLWLRQRMQESY--PTHIIPPLPEKHSFTK------HFDRFSPEFLKARELALNKFMTRIADHPVMSFNDHLHVFL 136

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BLAST of Sorting nexin-2 vs. Ensembl Nematostella
Match: EDO38324 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SD93])

HSP 1 Score: 52.373 bits (124), Expect = 4.184e-8
Identity = 41/112 (36.61%), Postives = 57/112 (50.89%), Query Frame = 3

Query:  264 FIEISVSYPEKLGSGMAAYFIYKINTKTNRPSFLHQEITVRRRFSDFLGLHERLKLKYLFAGCIIPPAPEKNAFGNTKLKLSKEDQT-NSEFXXXXXXXXXXYLQRIARHPL 596
            F+EI V  PE  G G   Y  Y++  +TN P F  +E +VRRR+SDF  L   L+     +  ++P  P K       L    +D     EF+E RR  LE ++ R+A HPL
Sbjct:   34 FLEIDVVNPETHGVGKKRYTDYELRMRTNLPVFKQKESSVRRRYSDFEWLRSELERD---SKIVVPALPGKAL--KRMLPFRGDDGIFEDEFIEDRRQGLEAFINRVAGHPL 140

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BLAST of Sorting nexin-2 vs. Ensembl Nematostella
Match: EDO46810 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RP73])

HSP 1 Score: 48.521 bits (114), Expect = 4.978e-6
Identity = 90/372 (24.19%), Postives = 153/372 (41.13%), Query Frame = 3

Query:  327 YKINTKTNRPSFLHQEITVRRRFSDFLGLHERLKLKYLFAGCIIPPAPEKNAFGNTKLKLSK-----EDQTNSEFXXXXXXXXXXYLQ--------------RIARHPLLVIDADFREFLEDDKELPKAVNTQVLSGANMKK----LFKNVGDAVGKITTKMDDCDQKDILWFDDKQVEMDNLDRHLSQIHCSFEHLISQRKELASQIKVFAQNCSQLS----------HVEEHNGLARALAQLXXXXXXXXXXXXRQAEVEFYTLLELLKDYLGMIGAVKEVLNERIRQYRVWQEAESNLNKKREQKARCEISGKVDKIPAFDLEIKECLNKVDRTREDFEKISKTIKTELEAFDTTKVIDFKEGIIKVLE 1343
            + ++TKT  P F   + +V R   +F+ LH+R      +AG IIPPAP K  F  ++ KL K      + T  EF + ++     YL               R+A HP L  D++F+ FLE   EL        + G N K+    LFK +   V ++        QKD+  F       ++  + L + H   +  + +   +    K    NC+ +              E+ GL + L +     E    +E R A  E   +++LL+ Y+    A K +L+ R +    ++ A   L+K R +                + EI E   +     E FE +S+  + EL  F   +V  F++ + +++E
Sbjct:   36 FTVHTKTTLPDFKESDFSVVREHEEFVWLHDRCVENEEYAGIIIPPAPPKPDFDVSREKLQKLGEGEGNMTKEEFQKMKQELEAEYLATFKKTVAMHEVFLTRLASHPSLRKDSNFKVFLEYKAELN-------VRGKNKKEKLGGLFKGLAKGVDEVLL----SGQKDVDEF------FESEKKFLVEYHNKLKDSVRKGDVMTRSHK----NCADVYIKISTGIASMGTSEYTGLDKFLNKTGDYFERARKLEGRVASDEDLKMVDLLRYYMRDTEAAKNLLHRRAKCLAEYENANKALDKARMK----------------NKEIAESAQQ--NASEKFEHMSEIARQELTDFKARRVQQFRKNLTELVE 368

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BLAST of Sorting nexin-2 vs. Ensembl Medaka
Match: snx2 (sorting nexin 2 [Source:NCBI gene;Acc:101172341])

HSP 1 Score: 325.865 bits (834), Expect = 2.817e-105
Identity = 174/383 (45.43%), Postives = 257/383 (67.10%), Query Frame = 3

Query:  267 IEISVSYPEKLGSGMAAYFIYKINTKTNRPSFLHQEITVRRRFSDFLGLHERLKLKYLFAGCIIPPAPEKNAFGNTKLKLSKEDQTNSEFXXXXXXXXXXYLQRIARHPLLVIDADFREFLEDDKELPKAVNTQVLSGANMKKLFKNVGDAVGKITTKMDDCDQKDILWFDDKQVEMDNLDRHLSQIHCSFEHLISQRKELASQIKVFAQNCSQLSHVEEHNGLARALAQLXXXXXXXXXXXXRQAEVEFYTLLELLKDYLGMIGAVKEVLNERIRQYRVWQEAESNLNKKREQKARCEISGKVDKIPAFDLEIKECLNKVDRTREDFEKISKTIKTELEAFDTTKVIDFKEGIIKVLEAMISSQEEIIHQWEKYIPDTAGIS 1415
            I ISVS PEK+G GM AY  YK+ TKT+   F  ++ +V+RRFSDFLGLH +L  KYL  G I+PPAPEK+  G TK+K+ KEDQ+++EF+E+RR+ALERYL R  +HP+L+ D D  +FLE   ELP+AVNTQ LS A + ++     +AV K+T KM++ D     WF++KQ   +NLD  L ++H S E L+  RKEL+     FA++ + L + E+H  L+RAL+QL+  +E+I  + + QA  +FY   ELL DY+ +I AVK V ++R++ ++ WQ+++  L KKRE +A+ + + K DK+     EIKE   KV +   DFE+ISKTI+ E+  F+  +V DFK  I+K LE+++ +Q+++I  WE ++P+   IS
Sbjct:  132 IHISVSDPEKVGDGMNAYMAYKVTTKTSVALFKQRDFSVKRRFSDFLGLHSKLASKYLHIGYIVPPAPEKSIVGMTKVKVGKEDQSSNEFVEKRRSALERYLMRTVKHPILLKDPDVLQFLES-SELPRAVNTQALSSAGILRMVNKAAEAVNKMTIKMNESDA----WFEEKQQHFENLDAQLRKLHASVECLVCHRKELSVNTAQFAKSAAMLGNSEDHTALSRALSQLAEVEEKIDQLHQDQANADFYLFSELLGDYVRLITAVKGVFDQRMKTWQKWQDSQMLLQKKREAEAKLQFTNKPDKLQQTKDEIKELEGKVQQGERDFEQISKTIRKEVSRFEKDRVKDFKMSIVKYLESLVQTQQQLIKYWEAFLPEAKAIS 509

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BLAST of Sorting nexin-2 vs. Ensembl Medaka
Match: snx2 (sorting nexin 2 [Source:NCBI gene;Acc:101172341])

HSP 1 Score: 313.153 bits (801), Expect = 2.381e-100
Identity = 173/387 (44.70%), Postives = 257/387 (66.41%), Query Frame = 3

Query:  267 IEISVSYPEKLGSGMAAYFIYKINTKTNRPSFLHQEITVRRRFSDFLGLHERLKLKYLFAGCIIPPAPEKNAFGNTKLKLSKEDQTNSEFXXXXXXXXXXYLQRIARHPLLVIDADFREFLEDDKELPKAVNTQVLSGANMKKLFKNVGDAVGKITTKMDDCDQKDILWFDDKQVEMDNLDRHLSQIHCSFEHLISQRKELASQIKVFAQNCSQLSHVEEHNGLARALAQLXXXXXXXXXXXXRQAEVEFYTLLELLKDYLGMIGAVKEVLNERIRQYRVWQEAESNLNKKREQKARCEISGKVDKIP----AFDLEIKECLNKVDRTREDFEKISKTIKTELEAFDTTKVIDFKEGIIKVLEAMISSQEEIIHQWEKYIPDTAGIS 1415
            I ISVS PEK+G GM AY  YK+ TKT+   F  ++ +V+RRFSDFLGLH +L  KYL  G I+PPAPEK+  G TK+K+ KEDQ+++EF+E+RR+ALERYL R  +HP+L+ D D  +FLE   ELP+AVNTQ LS A + ++     +AV K+T KM++ D     WF++KQ   +NLD  L ++H S E L+  RKEL+     FA++ + L + E+H  L+RAL+QL+  +E+I  + + QA  +FY   ELL DY+ +I AVK V ++R++ ++ WQ+++  L KKRE +A+ + + K DK+         EI+E   KV +   DFE+ISKTI+ E+  F+  +V DFK  I+K LE+++ +Q+++I  WE ++P+   IS
Sbjct:  132 IHISVSDPEKVGDGMNAYMAYKVTTKTSVALFKQRDFSVKRRFSDFLGLHSKLASKYLHIGYIVPPAPEKSIVGMTKVKVGKEDQSSNEFVEKRRSALERYLMRTVKHPILLKDPDVLQFLE-SSELPRAVNTQALSSAGILRMVNKAAEAVNKMTIKMNESDA----WFEEKQQHFENLDAQLRKLHASVECLVCHRKELSVNTAQFAKSAAMLGNSEDHTALSRALSQLAEVEEKIDQLHQDQANADFYLFSELLGDYVRLITAVKGVFDQRMKTWQKWQDSQMLLQKKREAEAKLQFTNKPDKLQQTKDEIKEEIEELEGKVQQGERDFEQISKTIRKEVSRFEKDRVKDFKMSIVKYLESLVQTQQQLIKYWEAFLPEAKAIS 513

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BLAST of Sorting nexin-2 vs. Ensembl Medaka
Match: snx1a (sorting nexin-1 [Source:NCBI gene;Acc:101163736])

HSP 1 Score: 285.419 bits (729), Expect = 7.687e-88
Identity = 161/381 (42.26%), Postives = 249/381 (65.35%), Query Frame = 3

Query:  273 ISVSYPEKLGSGMAAYFIYKINTKTNRPSFLHQEITVRRRFSDFLGLHERLKLKYLFAGCIIPPAPEKNAFGNTKLKLSKEDQTNSEFXXXXXXXXXXYLQRIARHPLLVIDADFREFLEDDKELPKAVNTQVLSGANMKKLFKNVGDAVGKITTKMDDCDQKDILWFDDKQVEMDNLDRHLSQIHCSFEHLISQRKELASQIKVFAQNCSQLSHVEEHNGLARALAQLXXXXXXXXXXXXRQAEVEFYTLLELLKDYLGMIGAVKEVLNERIRQYRVWQEAESNLNKKREQKARCEISGKVDKIPAFDLEIKECLNKVDRTREDFEKISKTIKTELEAFDTTKVIDFKEGIIKVLEAMISSQEEIIHQWEKYIPDTAGIS 1415
            +SV  PEK+G GM AY  YK++T+T  P F ++  TVRRRFSDFLGL+++L  K+   G I+PP PEK+  G TK+K+ KED ++++FLERRR ALERYLQR+  HPLL+ D D REFLE D ELP+AV+TQ LSGA   K+     DAV K+T KM++ D     WF++K  E+++ D+H  ++H   E L+  RKEL+     FA++ + L   E++  L+RAL+QL+  +++I  + + QA  + ++  EL+ DY+ ++GAV+   + RI+ ++ WQ+A++ L KKRE +A+   + K DK+     EI E   +V +   DFE++S T++ E+  F+  +  +FK  I K LE ++ SQ+++I  WE ++P+   I+
Sbjct:  293 VSVKDPEKVGDGMNAYMAYKVSTETTLPMFRNKLFTVRRRFSDFLGLYQKLSEKHGPNGLIVPPPPEKSILGMTKVKVGKEDSSSADFLERRRGALERYLQRVVNHPLLLQDPDVREFLEKD-ELPRAVSTQTLSGAGFLKMINKATDAVSKMTIKMNESD----AWFEEKLQEVESADQHFRKLHALVESLVVHRKELSLNTANFAKSAAMLGSAEDNTALSRALSQLAEVEDKIEQLHQDQAAYDTFSFAELIADYIRLLGAVRGSFDHRIKAWQRWQDAQAMLQKKREMEAKLLWANKPDKLQQAKEEIVEWEARVTQFERDFERVSATVRKEVLRFEKQRTKNFKRQITKYLELLLQSQQQLIKYWEAFLPEAKAIA 668

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BLAST of Sorting nexin-2 vs. Ensembl Medaka
Match: snx1b (sorting nexin 1b [Source:ZFIN;Acc:ZDB-GENE-050913-82])

HSP 1 Score: 213.772 bits (543), Expect = 1.005e-64
Identity = 126/293 (43.00%), Postives = 190/293 (64.85%), Query Frame = 3

Query:  492 TKLKLSKEDQTNSEFXXXXXXXXXXYLQRIARHPLLVIDADFREFLEDDKELPKAVNTQVLSGANMKKLFKNVGDAVGKITTKMDDCDQKDILWFDDKQVEMDNLDRHLSQIHCSFEHLISQRKELASQIKVFAQNCSQLSHVEEHNGLARALAQLXXXXXXXXXXXXRQAEVEFYTLLELLKDYLGMIGAVKEVLNERIRQYRVWQEAESNLNKKREQKARCEISGKVDKIPAFDLEIKECLNKVDRTREDFEKISKTIKTELEAFDTTKVIDFKEGIIKVLEAMISSQEEI 1370
            TK+K+  +D ++ EF+ERRRAALERYLQR+  HP LV D D REFLE D +LP+AVNTQ LSGA   K+     DAV K+T KM++ D     WF+DK  E++  ++ L ++H   + L++ RKEL     +FA++ + L + E++  L+RAL+QL+  ++++  + + QA  +F+ L ELL DY+ ++GAV+  L++R+R ++ WQEA+S L KKRE +A+   + K DK+     EI E   KV +   DF++I  T++ E   F+  K  DFK  IIK LEAM+ SQ+ +
Sbjct:    2 TKVKVGMDDPSSVEFVERRRAALERYLQRVVSHPSLVQDPDVREFLEKD-DLPRAVNTQTLSGAGFLKMINRASDAVNKMTIKMNESD----TWFEDKLQEVEAEEQQLRKLHSVVDSLVNHRKELCGNTAIFAKSMAMLGNSEDNTALSRALSQLAEVEDKMEQLHQEQAASDFFILAELLADYIRLLGAVRGCLDQRMRAWQRWQEAQSTLQKKRETEAKLLWANKPDKLQQAKDEITEWETKVTQYERDFDRIGMTVRKEFLRFEKDKAKDFKSQIIKYLEAMMKSQQRV 289

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BLAST of Sorting nexin-2 vs. Ensembl Medaka
Match: snx6 (sorting nexin 6 [Source:NCBI gene;Acc:101159712])

HSP 1 Score: 78.9518 bits (193), Expect = 2.478e-15
Identity = 93/363 (25.62%), Postives = 156/363 (42.98%), Query Frame = 3

Query:  327 YKINTKTNRPSFLHQEITVRRRFSDFLGLHERLKLKYLFAGCIIPPAPEKNAFGNTKLKLSKEDQ-----TNSEFXXXXXXXXXXYLQ--------------RIARHPLLVIDADFREFLEDDKELPKAVNTQVLSGANMKK----LFKN-VGDAVGKITTKMDDCDQKDILWFDDKQVEMDNLDRHLSQIHCSFEHLISQRKELASQIKVFAQNCSQLSHVEEHNGLARALAQLXXXXXXXXXXXXRQAEVEFYTLLELLKDYLGMIGAVKEVLNERIRQYRVWQEAESNLNKKREQKARCEISGKVDKIPAFDLEIKECLNKVDRTREDFEKISKTIKTELEAFDTTKVIDFKEGIIKVLE 1343
            + ++TK+  P+F   E +V R+  +F+ LH+       +AG IIPPAP +  F  ++ KL K  +     T  EF + ++     YL               R+A HP+L  D +F  FLE +++L        + G N K+     FKN V  A G +   + D D     +F+ ++  +      +       + +I   K  A  +   A +   L   ++   L +   ++S   E+   IE R A  E   L +LLK YL    A K++L  R R    ++ A   L+K R                A + ++ +  N        FEKIS++ K EL  F T +V  F++ ++++ E
Sbjct:   49 FTVHTKSTLPNFKQNEFSVVRQHEEFIWLHDSFVENEDYAGYIIPPAPPRPDFDASREKLQKLGEGEGSMTKEEFTKMKQELEAEYLAIFKKTVAMHEVFLCRVAAHPVLRKDLNFHVFLEYNQDLS-------VRGKNKKEKLEDFFKNVVKSADGVLVAGVKDVDD----FFEHEKTFLLEYHNRVKDSSAKCDRMIRSHKNAADDMNRIASSLYTLG-TQDSTDLCKFFLKVSELFEKTRKIEARVAADEDLKLADLLKYYLRESQAAKDLLYRRSRSLVDYENANKALDKAR----------------AKNRDVMQAENNQQLCCHKFEKISESAKQELIDFKTRRVAAFRKNLVELAE 383

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BLAST of Sorting nexin-2 vs. Planmine SMEST
Match: SMESG000016192.1 (SMESG000016192.1)

HSP 1 Score: 857.055 bits (2213), Expect = 0.000e+0
Identity = 441/446 (98.88%), Postives = 442/446 (99.10%), Query Frame = 3

Query:   81 MTDDDDIFEEAMENTDEFGVQTEIRLDEPTITRNASPPRTSVTEISNDRVPNQRKISKTGKFIEISVSYPEKLGSGMAAYFIYKINTKTNRPSFLHQEITVRRRFSDFLGLHERLKLKYLFAGCIIPPAPEKNAFGNTKLKLSKEDQTNSEFXXXXXXXXXXYLQRIARHPLLVIDADFREFLEDDKELPKAVNTQVLSGANMKKLFKNVGDAVGKITTKMDDCDQKDILWFDDKQVEMDNLDRHLSQIHCSFEHLISQRKELASQIKVFAQNCSQLSHVEEHNGLARALAQLXXXXXXXXXXXXRQAEVEFYTLLELLKDYLGMIGAVKEVLNERIRQYRVWQEAESNLNKKREQKARCEISGKVDKIPAFDLEIKECLNKVDRTREDFEKISKTIKTELEAFDTTKVIDFKEGIIKVLEAMISSQEEIIHQWEKYIPDTAGIST 1418
            MTDDDDIFEEAMENTDEFGVQTEIRLDEPTITRNASPPRTSVTEISNDRVPNQRKISKTGKFIEISVSYPEKLGSGMAAYFIYKINTKTNRPSFLHQEITVRRRFSDFLGLHERLKLKYLFAGCIIPPAPEKNAFGNTKLKLSKEDQTNSEFLERRRAALERYLQRIARHPLLVIDADFREFLEDDKELPKAVNTQVLSGANMKKLFKNVGDAVGKITTKMDDCDQ    WFDDKQVEMDNLDRHLSQIHCSFEHLISQRKELASQIKVFAQNCSQLSHVEEHNGLARALAQLSAAKEEISAIEERQAEVEFYTLLELLKDYLGMIGAVKEVLNERIRQYRVWQEAESNLNKKREQKARCE+SGKVDKIPAFDLEIKECLNKVDRTREDFEKISKTIKTELEAFDTTKVIDFKEGIIKVLEAMISSQEEIIHQWEKYIPDTAGIST
Sbjct:    1 MTDDDDIFEEAMENTDEFGVQTEIRLDEPTITRNASPPRTSVTEISNDRVPNQRKISKTGKFIEISVSYPEKLGSGMAAYFIYKINTKTNRPSFLHQEITVRRRFSDFLGLHERLKLKYLFAGCIIPPAPEKNAFGNTKLKLSKEDQTNSEFLERRRAALERYLQRIARHPLLVIDADFREFLEDDKELPKAVNTQVLSGANMKKLFKNVGDAVGKITTKMDDCDQ----WFDDKQVEMDNLDRHLSQIHCSFEHLISQRKELASQIKVFAQNCSQLSHVEEHNGLARALAQLSAAKEEISAIEERQAEVEFYTLLELLKDYLGMIGAVKEVLNERIRQYRVWQEAESNLNKKREQKARCELSGKVDKIPAFDLEIKECLNKVDRTREDFEKISKTIKTELEAFDTTKVIDFKEGIIKVLEAMISSQEEIIHQWEKYIPDTAGIST 442

[Close]

BLAST of Sorting nexin-2 vs. Planmine SMEST
Match: SMESG000066985.1 (SMESG000066985.1)

HSP 1 Score: 63.5438 bits (153), Expect = 1.622e-10
Identity = 47/162 (29.01%), Postives = 79/162 (48.77%), Query Frame = 3

Query:  324 IYKINTKTNRPSFLHQEITVRRRFSDFLGLHERLKLKYLFAGCIIPPAPEKNAFGNTKLKLSK--EDQTN---SEFXXXXXXXXXXY--------------LQRIARHPLLVIDADFREFLEDDKELPKAVNTQVLSGANMKKLFKNVGDAVGKITTKMDDC 752
            ++ ++TKT    F ++E +V+R+  +F+ LH++L+    +AG I PPAP K  F +++ KL K  E + N    +F + +      Y              LQR+A HP+L  D +F  FLE D  L        + G + K+ F      + ++T  MD+ 
Sbjct:   58 VFTVHTKTTLKQFKNKEFSVKRQHEEFVWLHDQLEETEDYAGVIFPPAPPKPDFDDSRDKLMKLSEAENNMPKDQFDKMKAELEAEYLATFKKTVAMHEVFLQRLAAHPILQNDVNFSIFLEYDSNLS-------VRGKSRKEKFTGF---IKQVTATMDET 209

[Close]

BLAST of Sorting nexin-2 vs. Planmine SMEST
Match: SMESG000066985.1 (SMESG000066985.1)

HSP 1 Score: 63.5438 bits (153), Expect = 1.762e-10
Identity = 47/162 (29.01%), Postives = 79/162 (48.77%), Query Frame = 3

Query:  324 IYKINTKTNRPSFLHQEITVRRRFSDFLGLHERLKLKYLFAGCIIPPAPEKNAFGNTKLKLSK--EDQTN---SEFXXXXXXXXXXY--------------LQRIARHPLLVIDADFREFLEDDKELPKAVNTQVLSGANMKKLFKNVGDAVGKITTKMDDC 752
            ++ ++TKT    F ++E +V+R+  +F+ LH++L+    +AG I PPAP K  F +++ KL K  E + N    +F + +      Y              LQR+A HP+L  D +F  FLE D  L        + G + K+ F      + ++T  MD+ 
Sbjct:   59 VFTVHTKTTLKQFKNKEFSVKRQHEEFVWLHDQLEETEDYAGVIFPPAPPKPDFDDSRDKLMKLSEAENNMPKDQFDKMKAELEAEYLATFKKTVAMHEVFLQRLAAHPILQNDVNFSIFLEYDSNLS-------VRGKSRKEKFTGF---IKQVTATMDET 210

[Close]

BLAST of Sorting nexin-2 vs. Planmine SMEST
Match: SMESG000075553.1 (SMESG000075553.1)

HSP 1 Score: 49.2914 bits (116), Expect = 4.984e-6
Identity = 40/114 (35.09%), Postives = 63/114 (55.26%), Query Frame = 3

Query:  291 EKLGSGMAAYFIYKINTKTN-RPSFLHQEITVRRRFSDFLGLHERLKLKYLFAGCIIPPAPEKNAFGNTKLKLSKEDQTNSEFXXXXXXXXXXYLQRIARHPLLVIDADFREFL 629
            +K  S +  + +Y I T  N RP       +V RR++DF  L +RL  +Y  A  I+PP P+K+        L+  ++ +  F+E RR ALE++LQR+  H +L +D +F  FL
Sbjct:   48 KKASSFLETFIVYTIQTTGNFRP------YSVERRYNDFQWLFQRLSDRYPMA--IVPPLPDKH-------NLTAIERFSGIFIELRRNALEKFLQRLTDHKILSLDKEFWAFL 146

The following BLAST results are available for this feature:

BLAST of Sorting nexin-2 vs. Ensembl Human
BLAST of Sorting nexin-2 vs. Ensembl Celegans
BLAST of Sorting nexin-2 vs. Ensembl Fly
BLAST of Sorting nexin-2 vs. Ensembl Zebrafish
BLAST of Sorting nexin-2 vs. Ensembl Xenopus
BLAST of Sorting nexin-2 vs. Ensembl Mouse
BLAST of Sorting nexin-2 vs. UniProt/SwissProt
BLAST of Sorting nexin-2 vs. TrEMBL
BLAST of Sorting nexin-2 vs. Ensembl Cavefish
BLAST of Sorting nexin-2 vs. Ensembl Sea Lamprey
BLAST of Sorting nexin-2 vs. Ensembl Yeast
BLAST of Sorting nexin-2 vs. Ensembl Nematostella
BLAST of Sorting nexin-2 vs. Ensembl Medaka
BLAST of Sorting nexin-2 vs. Planmine SMEST

BLAST of Sorting nexin-2 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
SNX2	9.980e-110	46.48	sorting nexin 2 [Source:HGNC Symbol;Acc:HGNC:11173...	[more]
SNX2	2.014e-109	42.37	sorting nexin 2 [Source:HGNC Symbol;Acc:HGNC:11173...	[more]
SNX1	2.003e-93	42.30	sorting nexin 1 [Source:HGNC Symbol;Acc:HGNC:11172...	[more]
SNX1	1.668e-90	42.74	sorting nexin 1 [Source:HGNC Symbol;Acc:HGNC:11172...	[more]
SNX1	2.089e-87	42.59	sorting nexin 1 [Source:HGNC Symbol;Acc:HGNC:11172...	[more]

BLAST of Sorting nexin-2 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
snx-1	8.006e-63	35.01	Sorting NeXin [Source:UniProtKB/TrEMBL;Acc:Q9GYJ9...	[more]
snx-1	8.006e-63	35.01	Sorting NeXin [Source:UniProtKB/TrEMBL;Acc:Q9GYJ9...	[more]
snx-6	1.227e-17	26.80	Sorting NeXin [Source:UniProtKB/TrEMBL;Acc:D9PTP8...	[more]
snx-6	1.227e-17	26.80	Sorting NeXin [Source:UniProtKB/TrEMBL;Acc:D9PTP8...	[more]
snx-6	1.416e-17	26.87	Sorting NeXin [Source:UniProtKB/TrEMBL;Acc:D9PTP8...	[more]

BLAST of Sorting nexin-2 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Snx1	1.025e-104	43.06	gene:FBgn0031534 transcript:FBtr0077517	[more]
Snx1	3.043e-103	43.06	gene:FBgn0031534 transcript:FBtr0343238	[more]
Snx6	1.964e-15	24.53	gene:FBgn0032005 transcript:FBtr0306170	[more]
Snx6	3.030e-14	24.53	gene:FBgn0032005 transcript:FBtr0079631	[more]
Snx3	1.535e-6	34.82	gene:FBgn0038065 transcript:FBtr0082641	[more]

BLAST of Sorting nexin-2 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
snx1a	2.357e-97	43.86	sorting nexin 1a [Source:ZFIN;Acc:ZDB-GENE-060302-...	[more]
snx1b	8.713e-86	42.82	sorting nexin 1b [Source:ZFIN;Acc:ZDB-GENE-050913-...	[more]
snx1b	3.156e-85	43.15	sorting nexin 1b [Source:ZFIN;Acc:ZDB-GENE-050913-...	[more]
snx2	9.557e-61	31.30	sorting nexin 2 [Source:ZFIN;Acc:ZDB-GENE-051120-4...	[more]
snx5	7.420e-16	23.48	sorting nexin 5 [Source:ZFIN;Acc:ZDB-GENE-040426-2...	[more]

BLAST of Sorting nexin-2 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
SNX2	1.554e-109	42.06	sorting nexin 2 [Source:NCBI gene;Acc:100492702]	[more]
SNX2	3.307e-105	41.70	sorting nexin 2 [Source:NCBI gene;Acc:100492702]	[more]
SNX2	9.764e-104	42.44	sorting nexin 2 [Source:NCBI gene;Acc:100492702]	[more]
SNX2	5.340e-100	42.76	sorting nexin 2 [Source:NCBI gene;Acc:100492702]	[more]
SNX2	4.096e-99	46.50	sorting nexin 2 [Source:NCBI gene;Acc:100492702]	[more]

BLAST of Sorting nexin-2 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Snx2	6.377e-110	42.16	sorting nexin 2 [Source:MGI Symbol;Acc:MGI:1915054...	[more]
Snx1	8.066e-95	42.04	sorting nexin 1 [Source:MGI Symbol;Acc:MGI:1928395...	[more]
Snx1	2.396e-23	47.78	sorting nexin 1 [Source:MGI Symbol;Acc:MGI:1928395...	[more]
Snx5	2.627e-16	24.31	sorting nexin 5 [Source:MGI Symbol;Acc:MGI:1916428...	[more]
Snx5	2.627e-16	24.31	sorting nexin 5 [Source:MGI Symbol;Acc:MGI:1916428...	[more]

BLAST of Sorting nexin-2 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q9CWK8\|SNX2_MOUSE	4.460e-109	42.16	Sorting nexin-2 OS=Mus musculus OX=10090 GN=Snx2 P...	[more]
sp\|O60749\|SNX2_HUMAN	9.672e-109	42.37	Sorting nexin-2 OS=Homo sapiens OX=9606 GN=SNX2 PE...	[more]
sp\|Q5R9A9\|SNX2_PONAB	1.058e-104	42.00	Sorting nexin-2 OS=Pongo abelii OX=9601 GN=SNX2 PE...	[more]
sp\|P0C220\|SNX2_MACFA	1.153e-104	42.00	Sorting nexin-2 OS=Macaca fascicularis OX=9541 GN=...	[more]
sp\|Q2TBW7\|SNX2_BOVIN	1.479e-104	42.15	Sorting nexin-2 OS=Bos taurus OX=9913 GN=SNX2 PE=2...	[more]

BLAST of Sorting nexin-2 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A1S3K472	1.155e-123	51.17	sorting nexin-2 OS=Lingula unguis OX=7574 GN=LOC10...	[more]
A0A023FLQ8	2.441e-123	44.60	Putative membrane coat complex retromer subunit vp...	[more]
A0A131XK28	2.877e-122	44.93	Putative sorting nexin OS=Hyalomma excavatum OX=25...	[more]
A0A023FZP4	1.237e-121	44.37	Putative membrane coat complex retromer subunit vp...	[more]
A0A131YSX6	1.410e-121	44.70	Sorting nexin-1/2 OS=Rhipicephalus appendiculatus ...	[more]

BLAST of Sorting nexin-2 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
snx1b	2.747e-99	42.41	sorting nexin-1-like [Source:NCBI gene;Acc:1030443...	[more]
snx2	3.292e-98	42.02	sorting nexin 2 [Source:ZFIN;Acc:ZDB-GENE-051120-4...	[more]
snx1b	5.510e-94	41.58	sorting nexin-1-like [Source:NCBI gene;Acc:1030443...	[more]
snx2	1.042e-92	41.43	sorting nexin 2 [Source:ZFIN;Acc:ZDB-GENE-051120-4...	[more]
snx1a	2.039e-83	40.47	sorting nexin 1a [Source:ZFIN;Acc:ZDB-GENE-060302-...	[more]

BLAST of Sorting nexin-2 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5


Match Name	E-value	Identity	Description
snx1a	1.159e-105	43.34	sorting nexin 1a [Source:ZFIN;Acc:ZDB-GENE-060302-...	[more]
ENSPMAT00000000227.1	6.597e-14	22.89	pep scaffold:Pmarinus_7.0:GL480786:1217:16989:1 ge...	[more]
ENSPMAT00000009855.1	4.261e-12	21.55	pep scaffold:Pmarinus_7.0:GL476399:593532:610067:1...	[more]
snx30	1.951e-10	34.45	sorting nexin family member 30 [Source:NCBI gene;A...	[more]
snx6	2.783e-10	24.59	sorting nexin 6 [Source:ZFIN;Acc:ZDB-GENE-050913-1...	[more]

BLAST of Sorting nexin-2 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 2


Match Name	E-value	Identity	Description
VPS5	2.508e-19	23.83	Nexin-1 homolog; required for localizing membrane ...	[more]
SNX4	1.258e-9	23.73	Sorting nexin; involved in retrieval of late-Golgi...	[more]

BLAST of Sorting nexin-2 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 4


Match Name	E-value	Identity	Description
EDO32102	3.777e-118	47.52	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO46895	2.234e-12	39.23	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO38324	4.184e-8	36.61	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO46810	4.978e-6	24.19	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of Sorting nexin-2 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
snx2	2.817e-105	45.43	sorting nexin 2 [Source:NCBI gene;Acc:101172341]	[more]
snx2	2.381e-100	44.70	sorting nexin 2 [Source:NCBI gene;Acc:101172341]	[more]
snx1a	7.687e-88	42.26	sorting nexin-1 [Source:NCBI gene;Acc:101163736]	[more]
snx1b	1.005e-64	43.00	sorting nexin 1b [Source:ZFIN;Acc:ZDB-GENE-050913-...	[more]
snx6	2.478e-15	25.62	sorting nexin 6 [Source:NCBI gene;Acc:101159712]	[more]

BLAST of Sorting nexin-2 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 4


Match Name	E-value	Identity	Description
SMESG000016192.1	0.000e+0	98.88	SMESG000016192.1	[more]
SMESG000066985.1	1.622e-10	29.01	SMESG000066985.1	[more]
SMESG000066985.1	1.762e-10	29.01	SMESG000066985.1	[more]
SMESG000075553.1	4.984e-6	35.09	SMESG000075553.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30017841 ID=SMED30017841|Name=Sorting nexin-2|organism=Schmidtea mediterranea sexual|type=transcript|length=1629bp
TTTTTTTATTTATTTCAAATTTCGGAAAAAAGTTTTGACTTTAAAGTTTT
ATTTAATAAAATAAAATTATTGTTTCCACAATGACTGATGATGATGATAT
TTTTGAAGAAGCTATGGAAAATACAGATGAATTTGGAGTTCAGACCGAAA
TAAGGTTAGATGAGCCAACTATTACGAGGAATGCATCACCTCCGAGAACC
AGTGTGACTGAAATATCAAATGATAGAGTACCTAACCAAAGAAAAATATC
TAAAACTGGAAAATTCATTGAGATTTCTGTCAGTTACCCAGAAAAACTTG
GATCGGGAATGGCCGCATATTTCATTTATAAAATTAATACTAAAACTAAT
CGGCCTTCATTTCTCCATCAGGAAATCACAGTTCGCCGTAGATTCTCTGA
TTTTCTAGGCTTGCATGAGCGATTGAAATTGAAGTACTTATTTGCCGGCT
GTATCATTCCTCCGGCTCCGGAAAAAAATGCCTTTGGCAATACAAAGTTG
AAGCTGTCGAAGGAAGACCAGACAAACAGCGAATTCCTGGAGAGGCGTCG
AGCTGCACTTGAGCGATATTTACAACGAATTGCTCGTCATCCGTTGCTTG
TTATTGACGCCGATTTCAGGGAGTTCCTGGAGGATGACAAGGAGCTACCG
AAGGCTGTCAACACTCAGGTGCTCTCGGGGGCAAACATGAAGAAACTCTT
CAAAAATGTTGGAGATGCTGTCGGTAAAATCACTACAAAAATGGACGATT
GCGATCAGAAGGACATTTTGTGGTTCGATGACAAACAGGTTGAGATGGAT
AATCTTGATCGCCATCTCAGTCAAATTCACTGCAGTTTCGAACACTTGAT
CAGCCAAAGAAAAGAACTTGCCTCACAGATCAAAGTATTTGCCCAAAACT
GTTCCCAGTTGTCACACGTTGAAGAACACAACGGATTGGCCAGAGCTCTG
GCACAATTGTCAGCTGCCAAAGAAGAAATAAGCGCCATTGAAGAACGCCA
AGCAGAAGTGGAATTTTACACACTTCTCGAACTGTTAAAAGACTATTTGG
GAATGATTGGTGCTGTAAAGGAGGTATTGAACGAGAGGATCCGCCAGTAT
CGAGTCTGGCAGGAAGCGGAATCGAATTTGAATAAGAAACGCGAGCAGAA
AGCGAGATGTGAAATATCGGGGAAGGTCGATAAAATTCCAGCGTTCGATT
TGGAAATCAAGGAGTGCCTCAACAAGGTCGACAGAACGAGAGAAGACTTT
GAAAAAATCTCCAAGACTATCAAAACGGAATTGGAAGCATTCGACACAAC
AAAAGTGATCGATTTCAAGGAAGGAATAATCAAGGTGCTCGAGGCAATGA
TTTCGAGTCAGGAAGAAATTATCCACCAATGGGAGAAATACATTCCCGAC
ACTGCCGGAATATCTACATGAACCCGTTGTTCCAGTTGAATCCAGTACAT
TTGACTATCTATACTACTGATTAATATTTACATTTGTCAGTAGTATAAAT
AGCTTTATTTTTACAAAATATAAGTTGAAATTGAAATATTTATTTGTTTA
TCGATTGATTAATTGATTGGAATTTGAAATTAGTATTGATCGATTTATTA
TTGAGTTTCAATATTTCAATAAATCACTG

protein sequence of SMED30017841-orf-1

>SMED30017841-orf-1 ID=SMED30017841-orf-1|Name=SMED30017841-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=447bp
MTDDDDIFEEAMENTDEFGVQTEIRLDEPTITRNASPPRTSVTEISNDRV
PNQRKISKTGKFIEISVSYPEKLGSGMAAYFIYKINTKTNRPSFLHQEIT
VRRRFSDFLGLHERLKLKYLFAGCIIPPAPEKNAFGNTKLKLSKEDQTNS
EFLERRRAALERYLQRIARHPLLVIDADFREFLEDDKELPKAVNTQVLSG
ANMKKLFKNVGDAVGKITTKMDDCDQKDILWFDDKQVEMDNLDRHLSQIH
CSFEHLISQRKELASQIKVFAQNCSQLSHVEEHNGLARALAQLSAAKEEI
SAIEERQAEVEFYTLLELLKDYLGMIGAVKEVLNERIRQYRVWQEAESNL
NKKREQKARCEISGKVDKIPAFDLEIKECLNKVDRTREDFEKISKTIKTE
LEAFDTTKVIDFKEGIIKVLEAMISSQEEIIHQWEKYIPDTAGIST*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **biological process**
Term	Definition
GO:0006886	intracellular protein transport
GO:0006897	endocytosis
GO:0042147	retrograde transport, endosome to Golgi

Vocabulary: **cellular component**
Term	Definition
GO:0030904	retromer complex

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000020	protonephridia
PLANA:0000026	gut
PLANA:0000034	epidermis
PLANA:0000070	intestinal phagocyte
PLANA:0002032	epidermal cell
PLANA:0003116	parenchymal cell

Vocabulary: **INTERPRO**
Term	Definition
IPR036871	PX_dom_sf
IPR027267	AH/BAR_dom_sf
IPR028660	SNX1
IPR039358	Sorting_nexin-like
IPR001683	Phox
IPR015404	Vps5_C

Vocabulary: **molecular function**
Term	Definition
GO:0035091	phosphatidylinositol binding

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
None	No IPR available	COILS	Coil	Coil	coord: 286..306
IPR001683	Phox homologous domain	SMART	SM00312	PX_2	coord: 60..186 e-value: 3.9E-31 score: 119.4
IPR001683	Phox homologous domain	PFAM	PF00787	PX	coord: 61..185 e-value: 2.5E-27 score: 95.1
IPR001683	Phox homologous domain	PROSITE	PS50195	PX	coord: 61..189 score: 19.952
IPR036871	PX domain superfamily	GENE3D	G3DSA:3.30.1520.10		coord: 61..186 e-value: 4.0E-41 score: 141.9
IPR036871	PX domain superfamily	SUPERFAMILY	SSF64268	PX domain	coord: 61..186
IPR015404	Sorting nexin Vps5-like, C-terminal	PFAM	PF09325	Vps5	coord: 204..439 e-value: 2.4E-67 score: 226.9
IPR027267	AH/BAR domain superfamily	GENE3D	G3DSA:1.20.1270.60		coord: 218..444 e-value: 8.9E-58 score: 197.6
IPR028660	Sorting nexin-1	PANTHER	PTHR10555:SF129	SORTING NEXIN-1	coord: 52..444
IPR039358	Sorting nexin-like	PANTHER	PTHR10555	SORTING NEXIN	coord: 52..444