SMED30017807

Overview
NameSMED30017807
Smed IDSMED30017807
Length (bp)511
Neoblast Clusters

Zeng et. al., 2018



 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30017807

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 8

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
pharynxSMED30017807SMESG000041639.1 dd_Smed_v4_9130_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
nervous systemSMED30017807SMESG000041639.1 dd_Smed_v4_9130_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30017807SMESG000041639.1 dd_Smed_v4_9130_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30017807SMESG000041639.1 dd_Smed_v4_9130_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30017807SMESG000041639.1 Contig41010newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30017807SMESG000041639.1 Contig41010uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
head regionSMED30017807SMESG000041639.1 dd_Smed_v6_9130_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017		whole organism asexual adult RNA-sequencing evidence
epidermisSMED30017807SMESG000041639.1 dd_Smed_v4_9130_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017		whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Alignments
SMED30017807 aligns in the following genomic locations:
Alignment LocationAlignment Score
v31.002770:17411..18058 -2442
Homology
[Close]
BLAST of SMED30017807 vs. Ensembl Human
Match: TMEM107 (transmembrane protein 107 [Source:HGNC Symbol;Acc:HGNC:28128])

HSP 1 Score: 56.6102 bits (135), Expect = 3.744e-10
Identity = 38/124 (30.65%), Postives = 66/124 (53.23%), Query Frame = -2 
Query:  151 QINGLIPTRFLVTISHLIGIISIFLKRERYTSIG----------TTEDQQFIAVXXXXXXXXXXXXXXXICGVTMFKNTYSLFISIIHVSGTVSLSYFITNKWSVSLFFNIFYGTILVPVALEI 492
            +++GL+P+RFL  ++HL+ +I++F  R+                  +D Q +A LS ++     EL  F+ GV+MF +T SL     H S +V+LS+FI  +W  + ++ IF     +P   E+
Sbjct:    3 RVSGLVPSRFLTLLAHLVVVITLFWSRDSNIQACLPLTFTPEEYDKQDIQLVAALSVTLGLFAVELAGFLSGVSMFNSTQSLISIGAHCSASVALSFFIFERWECTTYWYIFVFCSALPAVTEM 126
[Close]
BLAST of SMED30017807 vs. Ensembl Zebrafish
Match: tmem107l (transmembrane protein 107 like [Source:ZFIN;Acc:ZDB-GENE-090313-269])

HSP 1 Score: 62.003 bits (149), Expect = 1.821e-12
Identity = 43/127 (33.86%), Postives = 73/127 (57.48%), Query Frame = -2 
Query:  139 INGLIPTRFLVTISHLIGIISIFLKRE---------RYTSIG-TTEDQQFIAVXXXXXXXXXXXXXXXICGVTMFKNTYSLFISIIHVSGTVSLSYFITNKWSVSLFFNIFYGTILVPVALEIIYVI 489
            ++ L+P RFL  I+HL+ +I IF  RE          YT+   T ED + +  LS ++  L  EL+ F+CG++MF N  +L     H SG+V+L +F+  +W+ S+++ IF    ++P   E++ V+
Sbjct:    4 VSSLVPARFLTLIAHLVIVIIIFWSREYSVRACLPLDYTNEEYTAEDTRLVVALSVTLGLLAIELVGFLCGISMFNNNQALLSIGCHSSGSVALLFFMFEQWTCSIYWWIFSFCSVIPALYEMVIVV 130
[Close]
BLAST of SMED30017807 vs. Ensembl Zebrafish
Match: tmem107l (transmembrane protein 107 like [Source:ZFIN;Acc:ZDB-GENE-090313-269])

HSP 1 Score: 62.003 bits (149), Expect = 1.821e-12
Identity = 43/127 (33.86%), Postives = 73/127 (57.48%), Query Frame = -2 
Query:  139 INGLIPTRFLVTISHLIGIISIFLKRE---------RYTSIG-TTEDQQFIAVXXXXXXXXXXXXXXXICGVTMFKNTYSLFISIIHVSGTVSLSYFITNKWSVSLFFNIFYGTILVPVALEIIYVI 489
            ++ L+P RFL  I+HL+ +I IF  RE          YT+   T ED + +  LS ++  L  EL+ F+CG++MF N  +L     H SG+V+L +F+  +W+ S+++ IF    ++P   E++ V+
Sbjct:    4 VSSLVPARFLTLIAHLVIVIIIFWSREYSVRACLPLDYTNEEYTAEDTRLVVALSVTLGLLAIELVGFLCGISMFNNNQALLSIGCHSSGSVALLFFMFEQWTCSIYWWIFSFCSVIPALYEMVIVV 130
[Close]
BLAST of SMED30017807 vs. Ensembl Zebrafish
Match: tmem107l (transmembrane protein 107 like [Source:ZFIN;Acc:ZDB-GENE-090313-269])

HSP 1 Score: 62.003 bits (149), Expect = 1.821e-12
Identity = 43/127 (33.86%), Postives = 73/127 (57.48%), Query Frame = -2 
Query:  139 INGLIPTRFLVTISHLIGIISIFLKRE---------RYTSIG-TTEDQQFIAVXXXXXXXXXXXXXXXICGVTMFKNTYSLFISIIHVSGTVSLSYFITNKWSVSLFFNIFYGTILVPVALEIIYVI 489
            ++ L+P RFL  I+HL+ +I IF  RE          YT+   T ED + +  LS ++  L  EL+ F+CG++MF N  +L     H SG+V+L +F+  +W+ S+++ IF    ++P   E++ V+
Sbjct:    4 VSSLVPARFLTLIAHLVIVIIIFWSREYSVRACLPLDYTNEEYTAEDTRLVVALSVTLGLLAIELVGFLCGISMFNNNQALLSIGCHSSGSVALLFFMFEQWTCSIYWWIFSFCSVIPALYEMVIVV 130
[Close]
BLAST of SMED30017807 vs. Ensembl Zebrafish
Match: tmem107 (transmembrane protein 107 [Source:NCBI gene;Acc:406492])

HSP 1 Score: 48.1358 bits (113), Expect = 2.639e-7
Identity = 38/123 (30.89%), Postives = 62/123 (50.41%), Query Frame = -2 
Query:  151 INGLIPTRFLVTISHLIGIISIFLKRE---------RYTSIG-TTEDQQFIAVXXXXXXXXXXXXXXXICGVTMFKNTYSLFISIIHVSGTVSLSYFITNKWSVSLFFNIFYGTILVPVALEI 489
            +  L+P RFL   +HL+ II+IF  R+          +T     TED +    LS ++   + EL  F+ GV+MF +  +L   I H S  V LS+F+ ++W    ++ IF    + P  +E+
Sbjct:    4 LKSLVPARFLTLTAHLVIIITIFWSRDNNIQSCLPLEFTEDQYRTEDTRLTVALSVTLALFVLELAGFLSGVSMFNSNQALLSLITHSSACVCLSFFVFHQWPCWTYWIIFSICSVFPAVVEL 126
[Close]
BLAST of SMED30017807 vs. Ensembl Xenopus
Match: TMEM107 (transmembrane protein 107 [Source:NCBI gene;Acc:101731170])

HSP 1 Score: 50.8322 bits (120), Expect = 4.475e-8
Identity = 40/128 (31.25%), Postives = 63/128 (49.22%), Query Frame = -2 
Query:  148 INGLIPTRFLVTISHLIGIISIFLKRE--------------RYTSIGTTEDQQFIAVXXXXXXXXXXXXXXXICGVTMFKNTYSLFISIIHVSGTVSLSYFITNKWSVSLFFNIFYGTILVPVALEII 489
            I+ L+P+RFL   +HL+ +I IF  R+              +Y+S     D + I  LS ++     E   F+ GV+MF  T SL     H + +VSLS F++ +W  + ++ IF     +P   EII
Sbjct:    4 ISSLVPSRFLTLTAHLVIVIIIFWSRDNNVLACLPIDFTPQQYSS----RDTELIVALSVTLGLFAIEYAGFLSGVSMFNKTQSLLSLAAHCAASVSLSLFVSEQWECTSYWYIFGFCSALPAFTEII 127
[Close]
BLAST of SMED30017807 vs. Ensembl Mouse
Match: Tmem107 (transmembrane protein 107 [Source:MGI Symbol;Acc:MGI:1914160])

HSP 1 Score: 60.077 bits (144), Expect = 1.232e-11
Identity = 39/123 (31.71%), Postives = 66/123 (53.66%), Query Frame = -2 
Query:  154 QINGLIPTRFLVTISHLIGIISIFLKRE---------RYTSIG-TTEDQQFIAVXXXXXXXXXXXXXXXICGVTMFKNTYSLFISIIHVSGTVSLSYFITNKWSVSLFFNIFYGTILVPVALE 492
            +I+GL+P+RFL  ++HL+ +I++F  RE         ++T      +D Q +A L  ++     EL  F+ GV+MF +T SL     H S +V+LS+F+  +W  + ++ IF      P   E
Sbjct:    3 RISGLVPSRFLTLLAHLVVVITLFWSRESNIQACLPLKFTPEEYEKQDNQLVAALCLTLGLFAVELAGFLSGVSMFNSTQSLLSIAAHCSASVALSFFVFERWECTTYWYIFTFCSAFPAVTE 125
[Close]
BLAST of SMED30017807 vs. Ensembl Mouse
Match: Tmem107 (transmembrane protein 107 [Source:MGI Symbol;Acc:MGI:1914160])

HSP 1 Score: 60.077 bits (144), Expect = 1.379e-11
Identity = 37/112 (33.04%), Postives = 64/112 (57.14%), Query Frame = -2 
Query:  187 QINGLIPTRFLVTISHLIGIISIFLKRE---------RYTSIG-TTEDQQFIAVXXXXXXXXXXXXXXXICGVTMFKNTYSLFISIIHVSGTVSLSYFITNKWSVSLFFNIF 492
            +I+GL+P+RFL  ++HL+ +I++F  RE         ++T      +D Q +A L  ++     EL  F+ GV+MF +T SL     H S +V+LS+F+  +W  + ++ IF
Sbjct:    3 RISGLVPSRFLTLLAHLVVVITLFWSRESNIQACLPLKFTPEEYEKQDNQLVAALCLTLGLFAVELAGFLSGVSMFNSTQSLLSIAAHCSASVALSFFVFERWECTTYWYIF 114
[Close]
BLAST of SMED30017807 vs. UniProt/SwissProt
Match: sp|D3ZFW5|TM107_RAT (Transmembrane protein 107 OS=Rattus norvegicus OX=10116 GN=Tmem107 PE=3 SV=1)

HSP 1 Score: 60.4622 bits (145), Expect = 5.493e-11
Identity = 40/123 (32.52%), Postives = 66/123 (53.66%), Query Frame = -2 
Query:  154 QINGLIPTRFLVTISHLIGIISIFLKRE---------RYTSIG-TTEDQQFIAVXXXXXXXXXXXXXXXICGVTMFKNTYSLFISIIHVSGTVSLSYFITNKWSVSLFFNIFYGTILVPVALE 492
            +I+GL+P+RFL  ++HL+ +I++F  RE         ++T      +D Q +A L  ++     EL  F+ GV+MF +T SL     H S +V+LS+FI  +W  + ++ IF      P   E
Sbjct:    3 RISGLVPSRFLTLLAHLVIVITLFWSRESNIQACLPLKFTPEEYEKQDNQLVAALCLTLGLFAVELAGFLSGVSMFNSTQSLLSIAAHCSASVALSFFIFERWECTTYWYIFAFCSAFPAVTE 125
[Close]
BLAST of SMED30017807 vs. UniProt/SwissProt
Match: sp|Q9CPV0|TM107_MOUSE (Transmembrane protein 107 OS=Mus musculus OX=10090 GN=Tmem107 PE=1 SV=1)

HSP 1 Score: 60.077 bits (144), Expect = 8.619e-11
Identity = 39/123 (31.71%), Postives = 66/123 (53.66%), Query Frame = -2 
Query:  154 QINGLIPTRFLVTISHLIGIISIFLKRE---------RYTSIG-TTEDQQFIAVXXXXXXXXXXXXXXXICGVTMFKNTYSLFISIIHVSGTVSLSYFITNKWSVSLFFNIFYGTILVPVALE 492
            +I+GL+P+RFL  ++HL+ +I++F  RE         ++T      +D Q +A L  ++     EL  F+ GV+MF +T SL     H S +V+LS+F+  +W  + ++ IF      P   E
Sbjct:    3 RISGLVPSRFLTLLAHLVVVITLFWSRESNIQACLPLKFTPEEYEKQDNQLVAALCLTLGLFAVELAGFLSGVSMFNSTQSLLSIAAHCSASVALSFFVFERWECTTYWYIFTFCSAFPAVTE 125
[Close]
BLAST of SMED30017807 vs. UniProt/SwissProt
Match: sp|Q6UX40|TM107_HUMAN (Transmembrane protein 107 OS=Homo sapiens OX=9606 GN=TMEM107 PE=1 SV=1)

HSP 1 Score: 56.6102 bits (135), Expect = 1.798e-9
Identity = 38/124 (30.65%), Postives = 66/124 (53.23%), Query Frame = -2 
Query:  151 QINGLIPTRFLVTISHLIGIISIFLKRERYTSIG----------TTEDQQFIAVXXXXXXXXXXXXXXXICGVTMFKNTYSLFISIIHVSGTVSLSYFITNKWSVSLFFNIFYGTILVPVALEI 492
            +++GL+P+RFL  ++HL+ +I++F  R+                  +D Q +A LS ++     EL  F+ GV+MF +T SL     H S +V+LS+FI  +W  + ++ IF     +P   E+
Sbjct:    3 RVSGLVPSRFLTLLAHLVVVITLFWSRDSNIQACLPLTFTPEEYDKQDIQLVAALSVTLGLFAVELAGFLSGVSMFNSTQSLISIGAHCSASVALSFFIFERWECTTYWYIFVFCSALPAVTEM 126
[Close]
BLAST of SMED30017807 vs. UniProt/SwissProt
Match: sp|Q3B8H0|TM107_XENLA (Transmembrane protein 107 OS=Xenopus laevis OX=8355 GN=tmem107 PE=2 SV=1)

HSP 1 Score: 52.7582 bits (125), Expect = 4.755e-8
Identity = 42/124 (33.87%), Postives = 62/124 (50.00%), Query Frame = -2 
Query:  148 INGLIPTRFLVTISHLIGIISIFLKRER---------YTSIG-TTEDQQFIAVXXXXXXXXXXXXXXXICGVTMFKNTYSLFISIIHVSGTVSLSYFITNKWSVSLFFNIFYGTILVPVALEII 489
            I+ L+P+RFL   +HL+ +I+IF  RE          +T    ++ D + I  LS ++     E   F+ GV+MF  T SL     H S TVSL +F+   W  SL++ I      +P   EII
Sbjct:    4 ISSLVPSRFLTLTAHLVIVITIFWSRENNVLACLPINFTPQQFSSRDTELIIALSVTLGLFAVEYAGFLSGVSMFNKTQSLLSVGAHASATVSLLFFLFEGWDCSLYWWIMSFCSALPAVTEII 127
[Close]
BLAST of SMED30017807 vs. UniProt/SwissProt
Match: sp|Q6NZZ4|TM107_DANRE (Transmembrane protein 107 OS=Danio rerio OX=7955 GN=tmem107 PE=2 SV=1)

HSP 1 Score: 48.1358 bits (113), Expect = 1.992e-6
Identity = 38/123 (30.89%), Postives = 62/123 (50.41%), Query Frame = -2 
Query:  151 INGLIPTRFLVTISHLIGIISIFLKRE---------RYTSIG-TTEDQQFIAVXXXXXXXXXXXXXXXICGVTMFKNTYSLFISIIHVSGTVSLSYFITNKWSVSLFFNIFYGTILVPVALEI 489
            +  L+P RFL   +HL+ II+IF  R+          +T     TED +    LS ++   + EL  F+ GV+MF +  +L   I H S  V LS+F+ ++W    ++ IF    + P  +E+
Sbjct:    4 LKSLVPARFLTLTAHLVIIITIFWSRDNNIQSCLPLEFTEDQYRTEDTRLTVALSVTLALFVLELAGFLSGVSMFNSNQALLSLITHSSACVCLSFFVFHQWPCWTYWIIFSICSVFPAVVEL 126
[Close]
BLAST of SMED30017807 vs. TrEMBL
Match: A0A267H7X0 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig009266g1 PE=4 SV=1)

HSP 1 Score: 74.3294 bits (181), Expect = 1.341e-13
Identity = 55/129 (42.64%), Postives = 78/129 (60.47%), Query Frame = -2 
Query:  139 MQINGLIPTRFLVTISHLIGIISIFLKRERY--TSIGTT--------EDQQFIAVXXXXXXXXXXXXXXXICGVTMFKNTYSLFISIIHVSGTVSLSYFITNKWSVSLFFNIFYGTILVPVALEIIYVI 495
            M++NGLIP RFLV ISH++  ++IF+ R+ +   S+ TT        ED +FI VL+ S     FEL+SF+ GVTMF  T SLF +  H +G+V+L  F+ + W V+ FF IF   I  P   E+  +I
Sbjct:    1 MRVNGLIPARFLVLISHIVITVTIFISRDLHIKASLSTTYTTAEYNAEDLKFIIVLAVSCFLFAFELLSFLFGVTMFLPTQSLFSTASHFAGSVALLLFLLDSWPVNDFFYIFGFCIAFPAVTEVFAII 129
[Close]
BLAST of SMED30017807 vs. TrEMBL
Match: A0A2C9LGI1 (Uncharacterized protein OS=Biomphalaria glabrata OX=6526 GN=106053542 PE=4 SV=1)

HSP 1 Score: 65.4698 bits (158), Expect = 2.395e-10
Identity = 47/137 (34.31%), Postives = 69/137 (50.36%), Query Frame = -2 
Query:  115 MQINGLIPTRFLVTISHLIGIISIFLKR---------ERYTSIG-TTEDQQFIAVXXXXXXXXXXXXXXXICGVTMFKNTYSLFISIIHVSGTVSLSYFITNKWSVSLFFNIFYGTILVPVALEIIYVIFRLCIRHS 495
            MQ  GL+P RFL  I+HL+ +I +F  R         E YTS     +D + I  LS ++     E I F+ GVTMF    +L  +  H    ++L+YF+ ++W    ++ IF      P  +EIIY+I  LC R  
Sbjct:    1 MQGTGLVPARFLTLIAHLVLVIVVFWTRDENVKMCLPEDYTSSDFNDKDIEMIVALSITLGLFAVEFIGFMGGVTMFMPFQALLSTAAHSGAAIALAYFLFDQWPCHWYWYIFGFCSAFPACMEIIYIIGILCFRKG 137
[Close]
BLAST of SMED30017807 vs. TrEMBL
Match: A0A3S1H2Q8 (Uncharacterized protein OS=Elysia chlorotica OX=188477 GN=EGW08_021194 PE=4 SV=1)

HSP 1 Score: 65.0846 bits (157), Expect = 2.896e-10
Identity = 48/137 (35.04%), Postives = 72/137 (52.55%), Query Frame = -2 
Query:  115 MQINGLIPTRFLVTISHLIGIISIFLKRERY----------TSIGTTEDQQFIAVXXXXXXXXXXXXXXXICGVTMFKNTYSLFISIIHVSGTVSLSYFITNKWSVSLFFNIFYGTILVPVALEIIYVIFRLCIRHS 495
            MQ  GL+P RFL  I+HL+ +I IF  RE            TS    +D + +  LS ++ F L ELI F+ G+TMF N   L  ++ H +  ++LSYF+ + W    ++ IF      P  +EIIY++  +C R  
Sbjct:    1 MQSTGLVPARFLTIIAHLVLVIVIFWTREENIRACLPEDYTTSQYDDKDLEMLIGLSVTLGFFLVELIGFMGGITMFMNFQGLISTVAHSAAAITLSYFLFDAWPCEWYWYIFGFCSAFPALMEIIYIVGIMCFRKG 137
[Close]
BLAST of SMED30017807 vs. TrEMBL
Match: A0A3P8QFV9 (Transmembrane protein 107 like OS=Astatotilapia calliptera OX=8154 PE=4 SV=1)

HSP 1 Score: 64.6994 bits (156), Expect = 4.966e-10
Identity = 44/127 (34.65%), Postives = 66/127 (51.97%), Query Frame = -2 
Query:  139 INGLIPTRFLVTISHLIGIISIFLKRERYTSIG----------TTEDQQFIAVXXXXXXXXXXXXXXXICGVTMFKNTYSLFISIIHVSGTVSLSYFITNKWSVSLFFNIFYGTILVPVALEIIYVI 489
            ++ L+P RFL  I+HL+ +I+IF  RE                 TED+Q +  LS ++     EL  F  GV+MF  + SL     H SG+VSLS+F+  KW    ++ IF    ++P  +EI+  I
Sbjct:    4 VSSLVPARFLTIIAHLVIVITIFWSRENNVKACLPLDFTQEQYDTEDRQLVVALSVTLGLFAIELAGFFSGVSMFNCSQSLLSLAAHCSGSVSLSFFVFEKWECWTYWVIFATCSVLPALVEILLFI 130
[Close]
BLAST of SMED30017807 vs. TrEMBL
Match: A0A3Q2WMJ0 (Transmembrane protein 107 like OS=Haplochromis burtoni OX=8153 PE=4 SV=1)

HSP 1 Score: 64.6994 bits (156), Expect = 5.019e-10
Identity = 44/127 (34.65%), Postives = 66/127 (51.97%), Query Frame = -2 
Query:  139 INGLIPTRFLVTISHLIGIISIFLKRERYTSIG----------TTEDQQFIAVXXXXXXXXXXXXXXXICGVTMFKNTYSLFISIIHVSGTVSLSYFITNKWSVSLFFNIFYGTILVPVALEIIYVI 489
            ++ L+P RFL  I+HL+ +I+IF  RE                 TED+Q +  LS ++     EL  F  GV+MF  + SL     H SG+VSLS+F+  KW    ++ IF    ++P  +EI+  I
Sbjct:    4 VSSLVPARFLTIIAHLVIVITIFWSRENNVKACLPLDFTQEQYDTEDRQLVVALSVTLGLFAIELAGFFSGVSMFNCSQSLLSLAAHCSGSVSLSFFVFEKWECWTYWVIFATCSVLPALVEILLFI 130
[Close]
BLAST of SMED30017807 vs. Ensembl Cavefish
Match: tmem107l (transmembrane protein 107-like [Source:NCBI gene;Acc:103046146])

HSP 1 Score: 59.6918 bits (143), Expect = 1.410e-11
Identity = 41/123 (33.33%), Postives = 67/123 (54.47%), Query Frame = -2 
Query:  151 INGLIPTRFLVTISHLIGIISIFLKRE---------RYTSIG-TTEDQQFIAVXXXXXXXXXXXXXXXICGVTMFKNTYSLFISIIHVSGTVSLSYFITNKWSVSLFFNIFYGTILVPVALEI 489
            I+ L+P+RFL  I+HL+ +I+IF  RE          YT+     ED + +  LS ++     EL  F  G++MF N  SL  +  H SG V+L +F+  +W+ S+++ IF    ++P   E+
Sbjct:    4 ISSLVPSRFLTLIAHLVIVITIFWSRENNVRACLPLEYTNEEYNQEDTRLVVALSVTLGLFFVELAGFFSGISMFNNNQSLLSTACHASGAVALLFFLFEQWTCSIYWWIFGFCSVIPALYEM 126
[Close]
BLAST of SMED30017807 vs. Ensembl Cavefish
Match: tmem107 (transmembrane protein 107-like [Source:NCBI gene;Acc:103024721])

HSP 1 Score: 56.225 bits (134), Expect = 2.845e-10
Identity = 43/134 (32.09%), Postives = 67/134 (50.00%), Query Frame = -2 
Query:  118 INGLIPTRFLVTISHLIGIISIFLKRERYT----SIGTTEDQ------QFIAVXXXXXXXXXXXXXXXICGVTMFKNTYSLFISIIHVSGTVSLSYFITNKWSVSLFFNIFYGTILVPVALEIIYVIFRLCIRH 489
            IN L+P RFL   +HL+ +I+IF  R+        +  TEDQ      + +  LS ++     EL+ F  GV+MF     L     H S +VSLS+FI  +W    ++ IF    +VP   E++ +   LC++ 
Sbjct:    4 INSLVPARFLTLTAHLVIVITIFWSRDNNVRACLPLDFTEDQYRNEDNRLVIGLSVTLGLFALELLGFFSGVSMFNTNQGLLSVAAHCSASVSLSFFIFEQWECWYYWVIFSLCSVVPAVGELVQMFAVLCLKK 137
[Close]
BLAST of SMED30017807 vs. Ensembl Medaka
Match: tmem107 (transmembrane protein 107 [Source:NCBI gene;Acc:101155221])

HSP 1 Score: 56.225 bits (134), Expect = 2.401e-10
Identity = 40/117 (34.19%), Postives = 60/117 (51.28%), Query Frame = -2 
Query:  169 INGLIPTRFLVTISHLIGIISIFLKRERYTSIG----------TTEDQQFIAVXXXXXXXXXXXXXXXICGVTMFKNTYSLFISIIHVSGTVSLSYFITNKWSVSLFFNIFYGTILV 489
            I+ LIP RFL  I+HL+ +I+IF  RE                 TED++ +  LS ++     EL  F  GV+MF ++  L    +H S +VSLS+F+  +W    ++ IF    LV
Sbjct:    4 ISSLIPARFLTIIAHLVIVITIFWSRENNVKACLPLEFTQEQYDTEDRKLVVALSATLGLFAIELAGFFSGVSMFSSSQGLLSLAVHCSASVSLSFFVFEQWECWTYWVIFATCRLV 120
[Close]
BLAST of SMED30017807 vs. Planmine SMEST
Match: SMESG000041639.1 (SMESG000041639.1)

HSP 1 Score: 216.853 bits (551), Expect = 1.698e-73
Identity = 128/128 (100.00%), Postives = 128/128 (100.00%), Query Frame = -2 
Query:  112 MQINGLIPTRFLVTISHLIGIISIFLKRERYTSIGTTEDQQFIAVXXXXXXXXXXXXXXXICGVTMFKNTYSLFISIIHVSGTVSLSYFITNKWSVSLFFNIFYGTILVPVALEIIYVIFRLCIRHSL 495
            MQINGLIPTRFLVTISHLIGIISIFLKRERYTSIGTTEDQQFIAVLSFSIIFLLFELISFICGVTMFKNTYSLFISIIHVSGTVSLSYFITNKWSVSLFFNIFYGTILVPVALEIIYVIFRLCIRHSL
Sbjct:    1 MQINGLIPTRFLVTISHLIGIISIFLKRERYTSIGTTEDQQFIAVLSFSIIFLLFELISFICGVTMFKNTYSLFISIIHVSGTVSLSYFITNKWSVSLFFNIFYGTILVPVALEIIYVIFRLCIRHSL 128
[Close]
BLAST of SMED30017807 vs. Planmine SMEST
Match: SMESG000041627.1 (SMESG000041627.1)

HSP 1 Score: 128.257 bits (321), Expect = 3.741e-38
Identity = 75/127 (59.06%), Postives = 96/127 (75.59%), Query Frame = -2 
Query:  115 MQINGLIPTRFLVTISHLIGIISIFLKRERYTSIGTTEDQQFIAVXXXXXXXXXXXXXXXICGVTMFKNTYSLFISIIHVSGTVSLSYFITNKWSVSLFFNIFYGTILVPVALEIIYVIFRLCIRHS 495
            M+INGLIP RFLV +SHLI ++SI  +R+++T IGT ED QF   LS S++F+LFEL SFICGVTMFKNTYSLF+S+ HV+GT  LSYFI  KWS+  F+ IFY T++VP   E++ V  RL  R +
Sbjct:    1 MKINGLIPARFLVLLSHLIIVMSIIFQRDKHTKIGTMEDNQFFMGLSLSVMFILFELFSFICGVTMFKNTYSLFVSVAHVAGTSCLSYFINEKWSMEKFWYIFYSTVMVPGIAELVSVTSRLFFRQT 127
[Close]
BLAST of SMED30017807 vs. Planmine SMEST
Match: SMESG000041627.1 (SMESG000041627.1)

HSP 1 Score: 128.257 bits (321), Expect = 6.033e-38
Identity = 75/127 (59.06%), Postives = 96/127 (75.59%), Query Frame = -2 
Query:  115 MQINGLIPTRFLVTISHLIGIISIFLKRERYTSIGTTEDQQFIAVXXXXXXXXXXXXXXXICGVTMFKNTYSLFISIIHVSGTVSLSYFITNKWSVSLFFNIFYGTILVPVALEIIYVIFRLCIRHS 495
            M+INGLIP RFLV +SHLI ++SI  +R+++T IGT ED QF   LS S++F+LFEL SFICGVTMFKNTYSLF+S+ HV+GT  LSYFI  KWS+  F+ IFY T++VP   E++ V  RL  R +
Sbjct:    1 MKINGLIPARFLVLLSHLIIVMSIIFQRDKHTKIGTMEDNQFFMGLSLSVMFILFELFSFICGVTMFKNTYSLFVSVAHVAGTSCLSYFINEKWSMEKFWYIFYSTVMVPGIAELVSVTSRLFFRQT 127
[Close]
BLAST of SMED30017807 vs. Planmine SMEST
Match: SMESG000041627.1 (SMESG000041627.1)

HSP 1 Score: 123.25 bits (308), Expect = 3.666e-36
Identity = 71/115 (61.74%), Postives = 90/115 (78.26%), Query Frame = -2 
Query:  151 MQINGLIPTRFLVTISHLIGIISIFLKRERYTSIGTTEDQQFIAVXXXXXXXXXXXXXXXICGVTMFKNTYSLFISIIHVSGTVSLSYFITNKWSVSLFFNIFYGTILVPVALEI 495
            M+INGLIP RFLV +SHLI ++SI  +R+++T IGT ED QF   LS S++F+LFEL SFICGVTMFKNTYSLF+S+ HV+GT  LSYFI  KWS+  F+ IFY T++VP   E+
Sbjct:    1 MKINGLIPARFLVLLSHLIIVMSIIFQRDKHTKIGTMEDNQFFMGLSLSVMFILFELFSFICGVTMFKNTYSLFVSVAHVAGTSCLSYFINEKWSMEKFWYIFYSTVMVPGIAEL 115
[Close]
BLAST of SMED30017807 vs. Planmine SMEST
Match: SMESG000041627.1 (SMESG000041627.1)

HSP 1 Score: 123.25 bits (308), Expect = 5.819e-36
Identity = 71/117 (60.68%), Postives = 91/117 (77.78%), Query Frame = -2 
Query:  145 MQINGLIPTRFLVTISHLIGIISIFLKRERYTSIGTTEDQQFIAVXXXXXXXXXXXXXXXICGVTMFKNTYSLFISIIHVSGTVSLSYFITNKWSVSLFFNIFYGTILVPVALEIIY 495
            M+INGLIP RFLV +SHLI ++SI  +R+++T IGT ED QF   LS S++F+LFEL SFICGVTMFKNTYSLF+S+ HV+GT  LSYFI  KWS+  F+ IFY T++VP   E+ +
Sbjct:    1 MKINGLIPARFLVLLSHLIIVMSIIFQRDKHTKIGTMEDNQFFMGLSLSVMFILFELFSFICGVTMFKNTYSLFVSVAHVAGTSCLSYFINEKWSMEKFWYIFYSTVMVPGIAELQF 117
The following BLAST results are available for this feature:
BLAST of SMED30017807 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 1
Match NameE-valueIdentityDescription
TMEM1073.744e-1030.65transmembrane protein 107 [Source:HGNC Symbol;Acc:... [more]
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BLAST of SMED30017807 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of SMED30017807 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of SMED30017807 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 4
Match NameE-valueIdentityDescription
tmem107l1.821e-1233.86transmembrane protein 107 like [Source:ZFIN;Acc:ZD... [more]
tmem107l1.821e-1233.86transmembrane protein 107 like [Source:ZFIN;Acc:ZD... [more]
tmem107l1.821e-1233.86transmembrane protein 107 like [Source:ZFIN;Acc:ZD... [more]
tmem1072.639e-730.89transmembrane protein 107 [Source:NCBI gene;Acc:40... [more]
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BLAST of SMED30017807 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 1
Match NameE-valueIdentityDescription
TMEM1074.475e-831.25transmembrane protein 107 [Source:NCBI gene;Acc:10... [more]
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BLAST of SMED30017807 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 2
Match NameE-valueIdentityDescription
Tmem1071.232e-1131.71transmembrane protein 107 [Source:MGI Symbol;Acc:M... [more]
Tmem1071.379e-1133.04transmembrane protein 107 [Source:MGI Symbol;Acc:M... [more]
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BLAST of SMED30017807 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|D3ZFW5|TM107_RAT5.493e-1132.52Transmembrane protein 107 OS=Rattus norvegicus OX=... [more]
sp|Q9CPV0|TM107_MOUSE8.619e-1131.71Transmembrane protein 107 OS=Mus musculus OX=10090... [more]
sp|Q6UX40|TM107_HUMAN1.798e-930.65Transmembrane protein 107 OS=Homo sapiens OX=9606 ... [more]
sp|Q3B8H0|TM107_XENLA4.755e-833.87Transmembrane protein 107 OS=Xenopus laevis OX=835... [more]
sp|Q6NZZ4|TM107_DANRE1.992e-630.89Transmembrane protein 107 OS=Danio rerio OX=7955 G... [more]
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BLAST of SMED30017807 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A267H7X01.341e-1342.64Uncharacterized protein OS=Macrostomum lignano OX=... [more]
A0A2C9LGI12.395e-1034.31Uncharacterized protein OS=Biomphalaria glabrata O... [more]
A0A3S1H2Q82.896e-1035.04Uncharacterized protein OS=Elysia chlorotica OX=18... [more]
A0A3P8QFV94.966e-1034.65Transmembrane protein 107 like OS=Astatotilapia ca... [more]
A0A3Q2WMJ05.019e-1034.65Transmembrane protein 107 like OS=Haplochromis bur... [more]
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BLAST of SMED30017807 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 2
Match NameE-valueIdentityDescription
tmem107l1.410e-1133.33transmembrane protein 107-like [Source:NCBI gene;A... [more]
tmem1072.845e-1032.09transmembrane protein 107-like [Source:NCBI gene;A... [more]
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BLAST of SMED30017807 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of SMED30017807 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of SMED30017807 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of SMED30017807 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 1
Match NameE-valueIdentityDescription
tmem1072.401e-1034.19transmembrane protein 107 [Source:NCBI gene;Acc:10... [more]
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BLAST of SMED30017807 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000041639.11.698e-73100.00SMESG000041639.1[more]
SMESG000041627.13.741e-3859.06SMESG000041627.1[more]
SMESG000041627.16.033e-3859.06SMESG000041627.1[more]
SMESG000041627.13.666e-3661.74SMESG000041627.1[more]
SMESG000041627.15.819e-3660.68SMESG000041627.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30017807 ID=SMED30017807|Name=SMED30017807|organism=Schmidtea mediterranea sexual|type=transcript|length=511bp
ATATTGCAATTAAAATTAATTGAATATTTATAAATCCATTTCAATAATAA
TAATACATAAATTTAGAATCGATTGAATTAAAAATAAATTTCATCTATTT
AAATATCATCACAAACTATGTCGAATGCACAAACGGAAAATTACATAAAT
GATCTCCAAAGCCACTGGTACGAGTATTGTTCCGTAAAATATGTTAAAAA
ATAGAGATACAGACCATTTATTGGTTATAAAGTAGGACAGTGATACCGTT
CCGCTAACATGAATGATACTTATGAACAATGAATAAGTATTTTTAAACAT
AGTAACACCGCATATGAAACTAATCAATTCGAATAGAAGAAAAATAATTG
AGAATGACAACACAGCAATAAACTGCTGATCTTCAGTTGTCCCGATACTT
GTATATCTTTCCCTTTTAAGAAAAATTGATATAATACCTATAAGGTGACT
TATTGTTACTAAAAATCGTGTTGGAATTAAACCGTTAATTTGCATTTTAA
TTGTTTATCTT
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000016pharynx
PLANA:0000034epidermis
PLANA:0000099neuron
PLANA:0000418head
PLANA:0002032epidermal cell
Vocabulary: INTERPRO
TermDefinition
IPR029248TMEM107
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR029248Transmembrane protein 107PFAMPF14995TMEM107coord: 6..116
e-value: 4.5E-18
score: 65.9
IPR029248Transmembrane protein 107PANTHERPTHR34341FAMILY NOT NAMEDcoord: 3..124
NoneNo IPR availableTMHMMTMhelixcoord: 70..92
NoneNo IPR availableTMHMMTMhelixcoord: 41..63
NoneNo IPR availableTMHMMTMhelixcoord: 7..26
NoneNo IPR availableTMHMMTMhelixcoord: 102..124