PDZ domain-containing protein

Overview


Name	PDZ domain-containing protein
Smed ID	SMED30017785
Length (bp)	2257

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of PDZ domain-containing protein (SMED30017785) t-SNE clustered cells

Violin plots show distribution of expression levels for PDZ domain-containing protein (SMED30017785) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of PDZ domain-containing protein (SMED30017785) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for PDZ domain-containing protein (SMED30017785) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30017785

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 8

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
nervous system	SMED30017785	SMESG000023284.1	dd_Smed_v4_1210_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30017785	SMESG000023284.1	dd_Smed_v4_1210_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
anterior side	SMED30017785	SMESG000023284.1	dd_Smed_v4_1210_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
muscle cell	SMED30017785	SMESG000023284.1	dd_Smed_v4_1210_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30017785	SMESG000023284.1	Contig45443	uc_Smed_v2	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30017785	SMESG000023284.1	Contig45443	newmark_ests	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30017785	SMESG000023284.1	Contig11392	uc_Smed_v2	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30017785	SMESG000023284.1	Contig11392	newmark_ests	PMID:29674431 Fincher et al., 2018

Note: Hover over icons to view figure legend

Homology

[Close]

BLAST of PDZ domain-containing protein vs. Ensembl Human
Match: PDLIM7 (PDZ and LIM domain 7 [Source:HGNC Symbol;Acc:HGNC:22958])

HSP 1 Score: 50.447 bits (119), Expect = 1.074e-6
Identity = 34/110 (30.91%), Postives = 53/110 (48.18%), Query Frame = 2

Query:  371 PWGFRLQGGSDTGYPLSVQRVF-SGSPAEGILQRNDEIKIIDNSDVEHGTLKQVQDLIRTSGSQLNFIVVRDPNKEITNIDQSEEKISVQNARKMFASNE--NRSPQPFG 691
            PWGFRLQGG D   PLS+ R+   G  A+  +   D +  ID  +    T  + Q+ IR  G +L+  + R   + + +  Q     +    R  FA +   N++ +PFG
Sbjct:   13 PWGFRLQGGKDFNVPLSISRLTPGGKAAQAGVAVGDWVLSIDGENAGSLTHIEAQNKIRACGERLSLGLSR--AQPVQSKPQKASAPAADPPRYTFAPSVSLNKTARPFG 120

[Close]

BLAST of PDZ domain-containing protein vs. Ensembl Human
Match: PDLIM7 (PDZ and LIM domain 7 [Source:HGNC Symbol;Acc:HGNC:22958])

HSP 1 Score: 50.447 bits (119), Expect = 1.575e-6
Identity = 34/110 (30.91%), Postives = 53/110 (48.18%), Query Frame = 2

Query:  371 PWGFRLQGGSDTGYPLSVQRVF-SGSPAEGILQRNDEIKIIDNSDVEHGTLKQVQDLIRTSGSQLNFIVVRDPNKEITNIDQSEEKISVQNARKMFASNE--NRSPQPFG 691
            PWGFRLQGG D   PLS+ R+   G  A+  +   D +  ID  +    T  + Q+ IR  G +L+  + R   + + +  Q     +    R  FA +   N++ +PFG
Sbjct:   13 PWGFRLQGGKDFNVPLSISRLTPGGKAAQAGVAVGDWVLSIDGENAGSLTHIEAQNKIRACGERLSLGLSR--AQPVQSKPQKASAPAADPPRYTFAPSVSLNKTARPFG 120

[Close]

BLAST of PDZ domain-containing protein vs. Ensembl Human
Match: PDLIM7 (PDZ and LIM domain 7 [Source:HGNC Symbol;Acc:HGNC:22958])

HSP 1 Score: 50.8322 bits (120), Expect = 1.599e-6
Identity = 34/110 (30.91%), Postives = 53/110 (48.18%), Query Frame = 2

Query:  371 PWGFRLQGGSDTGYPLSVQRVF-SGSPAEGILQRNDEIKIIDNSDVEHGTLKQVQDLIRTSGSQLNFIVVRDPNKEITNIDQSEEKISVQNARKMFASNE--NRSPQPFG 691
            PWGFRLQGG D   PLS+ R+   G  A+  +   D +  ID  +    T  + Q+ IR  G +L+  + R   + + +  Q     +    R  FA +   N++ +PFG
Sbjct:   13 PWGFRLQGGKDFNVPLSISRLTPGGKAAQAGVAVGDWVLSIDGENAGSLTHIEAQNKIRACGERLSLGLSR--AQPVQSKPQKASAPAADPPRYTFAPSVSLNKTARPFG 120

[Close]

BLAST of PDZ domain-containing protein vs. Ensembl Human
Match: PDLIM3 (PDZ and LIM domain 3 [Source:HGNC Symbol;Acc:HGNC:20767])

HSP 1 Score: 51.9878 bits (123), Expect = 2.096e-6
Identity = 39/133 (29.32%), Postives = 53/133 (39.85%), Query Frame = 2

Query:  371 PWGFRLQGGSDTGYPLSVQRVFSGSPAEGI-LQRNDEIKIIDNSDVEHGTLKQVQDLIRTSGSQLNFIVVRDPNKEITNIDQSEE-----KISVQNARKMFASNENRSPQPFGQFGTEYHKKSNTLPTSLKIE 751
            PWGFRL GG D   PL + R+  GS A    L   D I  ID    E  T    QD I+ +  QL              ID+ E      ++S       F  N    PQ F   GT +++++     +  I+
Sbjct:   12 PWGFRLSGGIDFNQPLVITRITPGSKAAAANLCPGDVILAIDGFGTESMTHADAQDRIKAAAHQLCL-----------KIDRGETHLWSPQVSEDGKAHPFKINLESEPQEFKPIGTAHNRRAQPFVAAANID 133

[Close]

BLAST of PDZ domain-containing protein vs. Ensembl Human
Match: PDLIM7 (PDZ and LIM domain 7 [Source:HGNC Symbol;Acc:HGNC:22958])

HSP 1 Score: 50.8322 bits (120), Expect = 2.258e-6
Identity = 34/110 (30.91%), Postives = 53/110 (48.18%), Query Frame = 2

Query:  371 PWGFRLQGGSDTGYPLSVQRVF-SGSPAEGILQRNDEIKIIDNSDVEHGTLKQVQDLIRTSGSQLNFIVVRDPNKEITNIDQSEEKISVQNARKMFASNE--NRSPQPFG 691
            PWGFRLQGG D   PLS+ R+   G  A+  +   D +  ID  +    T  + Q+ IR  G +L+  + R   + + +  Q     +    R  FA +   N++ +PFG
Sbjct:   13 PWGFRLQGGKDFNVPLSISRLTPGGKAAQAGVAVGDWVLSIDGENAGSLTHIEAQNKIRACGERLSLGLSR--AQPVQSKPQKASAPAADPPRYTFAPSVSLNKTARPFG 120

[Close]

BLAST of PDZ domain-containing protein vs. Ensembl Fly
Match: Zasp66 (gene:FBgn0035917 transcript:FBtr0089568)

HSP 1 Score: 64.3142 bits (155), Expect = 8.337e-11
Identity = 33/86 (38.37%), Postives = 44/86 (51.16%), Query Frame = 2

Query:  326 MQTLNLRLTRDNLSRPWGFRLQGGSDTGYPLSVQRVFSGSPAEGILQRNDEIKIIDNSDVEHGTLKQVQDLIRTSGSQLNFIVVRD 583
            +    + L RD  + PWG RL GG+D   PL + RV  GSPA G L R D I  I   D    +    Q L R +G+++  +V RD
Sbjct:    5 LHEFAVVLLRDGQATPWGIRLVGGNDLDTPLIITRVQVGSPAHGELLRGDIISKIGEYDARDLSHADAQQLFRGAGNEIRLVVHRD 90

[Close]

BLAST of PDZ domain-containing protein vs. Ensembl Fly
Match: Zasp66 (gene:FBgn0035917 transcript:FBtr0301156)

HSP 1 Score: 64.6994 bits (156), Expect = 8.892e-11
Identity = 33/86 (38.37%), Postives = 44/86 (51.16%), Query Frame = 2

Query:  326 MQTLNLRLTRDNLSRPWGFRLQGGSDTGYPLSVQRVFSGSPAEGILQRNDEIKIIDNSDVEHGTLKQVQDLIRTSGSQLNFIVVRD 583
            +    + L RD  + PWG RL GG+D   PL + RV  GSPA G L R D I  I   D    +    Q L R +G+++  +V RD
Sbjct:    5 LHEFAVVLLRDGQATPWGIRLVGGNDLDTPLIITRVQVGSPAHGELLRGDIISKIGEYDARDLSHADAQQLFRGAGNEIRLVVHRD 90

[Close]

BLAST of PDZ domain-containing protein vs. Ensembl Fly
Match: Zasp66 (gene:FBgn0035917 transcript:FBtr0301154)

HSP 1 Score: 65.0846 bits (157), Expect = 9.937e-11
Identity = 33/86 (38.37%), Postives = 44/86 (51.16%), Query Frame = 2

Query:  326 MQTLNLRLTRDNLSRPWGFRLQGGSDTGYPLSVQRVFSGSPAEGILQRNDEIKIIDNSDVEHGTLKQVQDLIRTSGSQLNFIVVRD 583
            +    + L RD  + PWG RL GG+D   PL + RV  GSPA G L R D I  I   D    +    Q L R +G+++  +V RD
Sbjct:    5 LHEFAVVLLRDGQATPWGIRLVGGNDLDTPLIITRVQVGSPAHGELLRGDIISKIGEYDARDLSHADAQQLFRGAGNEIRLVVHRD 90

[Close]

BLAST of PDZ domain-containing protein vs. Ensembl Fly
Match: Zasp66 (gene:FBgn0035917 transcript:FBtr0089563)

HSP 1 Score: 65.0846 bits (157), Expect = 1.093e-10
Identity = 33/86 (38.37%), Postives = 44/86 (51.16%), Query Frame = 2

Query:  326 MQTLNLRLTRDNLSRPWGFRLQGGSDTGYPLSVQRVFSGSPAEGILQRNDEIKIIDNSDVEHGTLKQVQDLIRTSGSQLNFIVVRD 583
            +    + L RD  + PWG RL GG+D   PL + RV  GSPA G L R D I  I   D    +    Q L R +G+++  +V RD
Sbjct:    5 LHEFAVVLLRDGQATPWGIRLVGGNDLDTPLIITRVQVGSPAHGELLRGDIISKIGEYDARDLSHADAQQLFRGAGNEIRLVVHRD 90

[Close]

BLAST of PDZ domain-containing protein vs. Ensembl Fly
Match: Zasp52 (gene:FBgn0265991 transcript:FBtr0329910)

HSP 1 Score: 59.3066 bits (142), Expect = 1.713e-9
Identity = 35/83 (42.17%), Postives = 54/83 (65.06%), Query Frame = 2

Query:  329 QTLNLRLTRDNLSRPWGFRLQGGSDTGYPLSVQRVFSGSPAE-GILQRNDEIKIIDNSDVEHGTLKQVQDLIRTSGSQLNFIV 574
            Q L ++L+R + ++PWGFRLQGG+D   PL VQ+V +GS +E   LQ  D +  I++ DV +   K  QD++  SG+  NF++
Sbjct:    5 QLLQIKLSRFD-AQPWGFRLQGGTDFAQPLLVQKVNAGSLSEQAGLQPGDAVVKINDVDVFNLRHKDAQDIVVRSGN--NFVI 84

[Close]

BLAST of PDZ domain-containing protein vs. Ensembl Zebrafish
Match: ldb3b (LIM domain binding 3b [Source:ZFIN;Acc:ZDB-GENE-030131-6032])

HSP 1 Score: 52.7582 bits (125), Expect = 6.324e-7
Identity = 69/257 (26.85%), Postives = 108/257 (42.02%), Query Frame = 2

Query:  371 PWGFRLQGGSDTGYPLSVQRVFSGS-PAEGILQRNDEIKIIDNSDVEHGTLKQVQDLIRTSGSQLNFIVVRD--------------------PN-KEITNIDQSEEKISVQN--ARKMFASNENRSPQPFGQFG--TEYHKKSNTLPTSLKIETNHEFYEQRNDTARHHEMNDEEDAADYSFMTLPV--------SERKKLFAKPDENLTTRSMPRQRSYSFRPSQKSNQIFPKTQSSIYQRKPQEFGWAPSKEKFE 1039
            PWGFRLQGG D    L++ R+  GS  A G L + D I  ID    E  T  + Q+ I+ + ++L+  + R                     P+ K I N   ++E +   N  A K  A + ++  +  G  G  T  H + NT P S+  +            AR +EM+  +D+A     +LP+        S   +   KPD+     S   +R+ + +   KS +I      + Y + P E     S+EKFE
Sbjct:   13 PWGFRLQGGKDFNMSLTISRITPGSKAASGNLNQGDIITAIDGVSTEGMTHLEAQNKIKAATTKLSLTMQRSRRPAPVPTATPRMDSPMPVIPHQKVIANTAATQEYVPSFNPIALKDSALSTHKPIEVKGPGGKATIIHAQYNT-PISMYSQDAIMDAIAGQAQARGNEMSG-DDSAGSPLASLPIKDPLVDSASPVYQAVIKPDDKGLEMSEWARRAANLQ--SKSFRILAHITGTEYLQDPDEEALRKSREKFE 265

[Close]

Query:  371 PWGFRLQGGSDTGYPLSVQRVFSGS-PAEGILQRNDEIKIIDNSDVEHGTLKQVQDLIRTSGSQLNFIVVRD--------------------PN-KEITNIDQSEEKISVQN--ARKMFASNENRSPQPFGQFG--TEYHKKSNTLPTSLKIETNHEFYEQRNDTARHHEMNDEEDAADYSFMTLPV--------SERKKLFAKPDENLTTRSMPRQRSYSFRPSQKSNQIFPKTQSSIYQRKPQEFGWAPSKEKFE 1039
            PWGFRLQGG D    L++ R+  GS  A G L + D I  ID    E  T  + Q+ I+ + ++L+  + R                     P+ K I N   ++E +   N  A K  A + ++  +  G  G  T  H + NT P S+  +            AR +EM+  +D+A     +LP+        S   +   KPD+     S   +R+ + +   KS +I      + Y + P E     S+EKFE
Sbjct:   13 PWGFRLQGGKDFNMSLTISRITPGSKAASGNLNQGDIITAIDGVSTEGMTHLEAQNKIKAATTKLSLTMQRSRRPAPVPTATPRMDSPMPVIPHQKVIANTAATQEYVPSFNPIALKDSALSTHKPIEVKGPGGKATIIHAQYNT-PISMYSQDAIMDAIAGQAQARGNEMSG-DDSAGSPLASLPIKDPLVDSASPVYQAVIKPDDKGLEMSEWARRAANLQ--SKSFRILAHITGTEYLQDPDEEALRKSREKFE 265

[Close]

Query:  371 PWGFRLQGGSDTGYPLSVQRVFSGS-PAEGILQRNDEIKIIDNSDVEHGTLKQVQDLIRTSGSQLNFIVVRD--------------------PN-KEITNIDQSEEKISVQN--ARKMFASNENRSPQPFGQFG--TEYHKKSNTLPTSLKIETNHEFYEQRNDTARHHEMNDEEDAADYSFMTLPV--------SERKKLFAKPDENLTTRSMPRQRSYSFRPSQKSNQIFPKTQSSIYQRKPQEFGWAPSKEKFE 1039
            PWGFRLQGG D    L++ R+  GS  A G L + D I  ID    E  T  + Q+ I+ + ++L+  + R                     P+ K I N   ++E +   N  A K  A + ++  +  G  G  T  H + NT P S+  +            AR +EM+  +D+A     +LP+        S   +   KPD+     S   +R+ + +   KS +I      + Y + P E     S+EKFE
Sbjct:   13 PWGFRLQGGKDFNMSLTISRITPGSKAASGNLNQGDIITAIDGVSTEGMTHLEAQNKIKAATTKLSLTMQRSRRPAPVPTATPRMDSPMPVIPHQKVIANTAATQEYVPSFNPIALKDSALSTHKPIEVKGPGGKATIIHAQYNT-PISMYSQDAIMDAIAGQAQARGNEMSG-DDSAGSPLASLPIKDPLVDSASPVYQAVIKPDDKGLEMSEWARRAANLQ--SKSFRILAHITGTEYLQDPDEEALRKSREKFE 265

[Close]

BLAST of PDZ domain-containing protein vs. Ensembl Zebrafish
Match: ldb3b (LIM domain binding 3b [Source:ZFIN;Acc:ZDB-GENE-030131-6032])

HSP 1 Score: 50.8322 bits (120), Expect = 9.175e-7
Identity = 27/71 (38.03%), Postives = 39/71 (54.93%), Query Frame = 2

Query:  371 PWGFRLQGGSDTGYPLSVQRVFSGS-PAEGILQRNDEIKIIDNSDVEHGTLKQVQDLIRTSGSQLNFIVVR 580
            PWGFRLQGG D    L++ R+  GS  A G L + D I  ID    E  T  + Q+ I+ + ++L+  + R
Sbjct:   13 PWGFRLQGGKDFNMSLTISRITPGSKAASGNLNQGDIITAIDGVSTEGMTHLEAQNKIKAATTKLSLTMQR 83

[Close]

BLAST of PDZ domain-containing protein vs. Ensembl Zebrafish
Match: ldb3b (LIM domain binding 3b [Source:ZFIN;Acc:ZDB-GENE-030131-6032])

HSP 1 Score: 50.8322 bits (120), Expect = 1.344e-6
Identity = 27/71 (38.03%), Postives = 39/71 (54.93%), Query Frame = 2

Query:  371 PWGFRLQGGSDTGYPLSVQRVFSGS-PAEGILQRNDEIKIIDNSDVEHGTLKQVQDLIRTSGSQLNFIVVR 580
            PWGFRLQGG D    L++ R+  GS  A G L + D I  ID    E  T  + Q+ I+ + ++L+  + R
Sbjct:   10 PWGFRLQGGKDFNMSLTISRITPGSKAASGNLNQGDIITAIDGVSTEGMTHLEAQNKIKAATTKLSLTMQR 80

[Close]

BLAST of PDZ domain-containing protein vs. Ensembl Xenopus
Match: aldh4a1 (aldehyde dehydrogenase 4 family member A1 [Source:Xenbase;Acc:XB-GENE-959460])

HSP 1 Score: 51.2174 bits (121), Expect = 6.959e-6
Identity = 27/78 (34.62%), Postives = 43/78 (55.13%), Query Frame = 2

Query:  371 PWGFRLQGGSDTGYPLSVQRVFSGSPAEGILQRNDEIKIIDNSDVEHGTLKQVQDLIRTSGSQLNFIVVRDPNKEITN 604
            PWGF L+GG + G PL + +V  G+ A  IL   DEI  I++  +  G  ++   L++ S   L  IV R  + +++N
Sbjct:   49 PWGFTLKGGKEHGEPLIITKVEDGNKAADILMAGDEIVNINDQQL-LGYRQEAICLVKGSHKILKMIVKRSSSHDLSN 125

[Close]

BLAST of PDZ domain-containing protein vs. Ensembl Mouse
Match: Pdlim3 (PDZ and LIM domain 3 [Source:MGI Symbol;Acc:MGI:1859274])

HSP 1 Score: 52.373 bits (124), Expect = 1.131e-6
Identity = 39/133 (29.32%), Postives = 54/133 (40.60%), Query Frame = 2

Query:  371 PWGFRLQGGSDTGYPLSVQRVFSGSPAEGI-LQRNDEIKIIDNSDVEHGTLKQVQDLIRTSGSQLNFIVVRDPNKEITNIDQSEEK-----ISVQNARKMFASNENRSPQPFGQFGTEYHKKSNTLPTSLKIE 751
            PWGFRL GG D   PL + R+  GS A    L   D I  ID    E  T    QD I+ +  QL              ID++E +     +S       F  N    PQ F   GT +++++     +  I+
Sbjct:   12 PWGFRLSGGIDFNQPLVITRITPGSKAAAANLCPGDVILAIDGFGTESMTHADAQDRIKAASYQLCL-----------KIDRAETRLWSPQVSEDGKAHPFKINLEAEPQEFKPIGTAHNRRAQPFVAAANID 133

[Close]

BLAST of PDZ domain-containing protein vs. Ensembl Mouse
Match: Pdlim7 (PDZ and LIM domain 7 [Source:MGI Symbol;Acc:MGI:1914649])

HSP 1 Score: 52.373 bits (124), Expect = 1.539e-6
Identity = 52/195 (26.67%), Postives = 78/195 (40.00%), Query Frame = 2

Query:  371 PWGFRLQGGSDTGYPLSVQRVF-SGSPAEGILQRNDEIKIIDNSDVEHGTLKQVQDLIRTSGSQLNFIVVRDPNKEITNIDQSEEKISVQNARKMFA--SNENRSPQPFGQFGTEYHKKSNTLPTSLKIETNHEFYEQ-RNDTARHHEMNDEED-------AADYSFMTLPVSERKKLFAKPDENLTTRS--MPR 916
            PWGFRLQGG D   PLS+ R+   G  A+  +   D +  ID  +    T  + Q+ IR  G +L+  + R   + + +  Q          R  FA  ++ N++ +PFG             PT   +  N +   Q   D ++   M D ED           SF  L      +    PDE    +S  +PR
Sbjct:   13 PWGFRLQGGKDFNVPLSISRLTPGGKAAQAGVAVGDWVLNIDGENAGSLTHIEAQNKIRACGERLSLGLSR--AQPVQSKPQKALTPPADPPRYTFAPSASLNKTARPFGA----------PPPTDSTLRQNGQLLRQPVPDASKQRLMEDTEDWRPRPGTGQSRSFRILAHLTGTEFMQDPDEEFMKKSSQVPR 195

[Close]

Query:  371 PWGFRLQGGSDTGYPLSVQRVF-SGSPAEGILQRNDEIKIIDNSDVEHGTLKQVQDLIRTSGSQLNFIVVRDPNKEITNIDQSEEKISVQNARKMFA--SNENRSPQPFGQFGTEYHKKSNTLPTSLKIETNHEFYEQ-RNDTARHHEMNDEED-------AADYSFMTLPVSERKKLFAKPDENLTTRS--MPR 916
            PWGFRLQGG D   PLS+ R+   G  A+  +   D +  ID  +    T  + Q+ IR  G +L+  + R   + + +  Q          R  FA  ++ N++ +PFG             PT   +  N +   Q   D ++   M D ED           SF  L      +    PDE    +S  +PR
Sbjct:   13 PWGFRLQGGKDFNVPLSISRLTPGGKAAQAGVAVGDWVLNIDGENAGSLTHIEAQNKIRACGERLSLGLSR--AQPVQSKPQKALTPPADPPRYTFAPSASLNKTARPFGA----------PPPTDSTLRQNGQLLRQPVPDASKQRLMEDTEDWRPRPGTGQSRSFRILAHLTGTEFMQDPDEEFMKKSSQVPR 195

[Close]

BLAST of PDZ domain-containing protein vs. Ensembl Mouse
Match: Pdlim7 (PDZ and LIM domain 7 [Source:MGI Symbol;Acc:MGI:1914649])

HSP 1 Score: 50.8322 bits (120), Expect = 1.700e-6
Identity = 50/190 (26.32%), Postives = 75/190 (39.47%), Query Frame = 2

Query:  371 PWGFRLQGGSDTGYPLSVQRVF-SGSPAEGILQRNDEIKIIDNSDVEHGTLKQVQDLIRTSGSQLNFIVVRDPNKEITNIDQSEEKISVQNARKMFA--SNENRSPQPFGQFGTEYHKKSNTLPTSLKIETNHEFYEQ-RNDTARHHEMNDEED-------AADYSFMTLPVSERKKLFAKPDENLTTRS 907
            PWGFRLQGG D   PLS+ R+   G  A+  +   D +  ID  +    T  + Q+ IR  G +L+  + R   + + +  Q          R  FA  ++ N++ +PFG             PT   +  N +   Q   D ++   M D ED           SF  L      +    PDE    +S
Sbjct:   13 PWGFRLQGGKDFNVPLSISRLTPGGKAAQAGVAVGDWVLNIDGENAGSLTHIEAQNKIRACGERLSLGLSR--AQPVQSKPQKALTPPADPPRYTFAPSASLNKTARPFGA----------PPPTDSTLRQNGQLLRQPVPDASKQRLMEDTEDWRPRPGTGQSRSFRILAHLTGTEFMQDPDEEFMKKS 190

[Close]

BLAST of PDZ domain-containing protein vs. Ensembl Mouse
Match: Pdlim7 (PDZ and LIM domain 7 [Source:MGI Symbol;Acc:MGI:1914649])

HSP 1 Score: 48.521 bits (114), Expect = 2.039e-6
Identity = 34/110 (30.91%), Postives = 53/110 (48.18%), Query Frame = 2

Query:  371 PWGFRLQGGSDTGYPLSVQRVF-SGSPAEGILQRNDEIKIIDNSDVEHGTLKQVQDLIRTSGSQLNFIVVRDPNKEITNIDQSEEKISVQNARKMFA--SNENRSPQPFG 691
            PWGFRLQGG D   PLS+ R+   G  A+  +   D +  ID  +    T  + Q+ IR  G +L+  + R   + + +  Q          R  FA  ++ N++ +PFG
Sbjct:   13 PWGFRLQGGKDFNVPLSISRLTPGGKAAQAGVAVGDWVLNIDGENAGSLTHIEAQNKIRACGERLSLGLSR--AQPVQSKPQKALTPPADPPRYTFAPSASLNKTARPFG 120

[Close]

BLAST of PDZ domain-containing protein vs. UniProt/SwissProt
Match: sp|A1ZA47|ZASP_DROME (PDZ and LIM domain protein Zasp OS=Drosophila melanogaster OX=7227 GN=Zasp52 PE=1 SV=2)

HSP 1 Score: 61.6178 bits (148), Expect = 3.085e-8
Identity = 35/83 (42.17%), Postives = 54/83 (65.06%), Query Frame = 2

Query:  329 QTLNLRLTRDNLSRPWGFRLQGGSDTGYPLSVQRVFSGSPAE-GILQRNDEIKIIDNSDVEHGTLKQVQDLIRTSGSQLNFIV 574
            Q L ++L+R + ++PWGFRLQGG+D   PL VQ+V +GS +E   LQ  D +  I++ DV +   K  QD++  SG+  NF++
Sbjct:    5 QLLQIKLSRFD-AQPWGFRLQGGTDFAQPLLVQKVNAGSLSEQAGLQPGDAVVKINDVDVFNLRHKDAQDIVVRSGN--NFVI 84

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BLAST of PDZ domain-containing protein vs. UniProt/SwissProt
Match: sp|Q3SYZ8|PDLI3_BOVIN (PDZ and LIM domain protein 3 OS=Bos taurus OX=9913 GN=PDLIM3 PE=2 SV=1)

HSP 1 Score: 53.1434 bits (126), Expect = 4.433e-6
Identity = 38/133 (28.57%), Postives = 54/133 (40.60%), Query Frame = 2

Query:  371 PWGFRLQGGSDTGYPLSVQRVFSGSPAEGI-LQRNDEIKIIDNSDVEHGTLKQVQDLIRTSGSQLNFIVVRDPNKEITNIDQSEEK-----ISVQNARKMFASNENRSPQPFGQFGTEYHKKSNTLPTSLKIE 751
            PWGFRL GG D   PL + R+  GS A    L   D I  ID    E  T    QD I+ +G QL              ID++E +     ++       F  N    PQ F   G  +++++     +  I+
Sbjct:   12 PWGFRLSGGIDFNQPLVITRITPGSKAAAANLCPGDVILAIDGFGTESMTHADAQDRIKAAGHQLCL-----------KIDRAEARLWSPQVTEDGKAHPFKINLESEPQEFKPIGAAHNRRAQPFVAAANID 133

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BLAST of PDZ domain-containing protein vs. UniProt/SwissProt
Match: sp|O70209|PDLI3_MOUSE (PDZ and LIM domain protein 3 OS=Mus musculus OX=10090 GN=Pdlim3 PE=1 SV=1)

HSP 1 Score: 52.373 bits (124), Expect = 7.912e-6
Identity = 39/133 (29.32%), Postives = 54/133 (40.60%), Query Frame = 2

Query:  371 PWGFRLQGGSDTGYPLSVQRVFSGSPAEGI-LQRNDEIKIIDNSDVEHGTLKQVQDLIRTSGSQLNFIVVRDPNKEITNIDQSEEK-----ISVQNARKMFASNENRSPQPFGQFGTEYHKKSNTLPTSLKIE 751
            PWGFRL GG D   PL + R+  GS A    L   D I  ID    E  T    QD I+ +  QL              ID++E +     +S       F  N    PQ F   GT +++++     +  I+
Sbjct:   12 PWGFRLSGGIDFNQPLVITRITPGSKAAAANLCPGDVILAIDGFGTESMTHADAQDRIKAASYQLCL-----------KIDRAETRLWSPQVSEDGKAHPFKINLEAEPQEFKPIGTAHNRRAQPFVAAANID 133

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BLAST of PDZ domain-containing protein vs. TrEMBL
Match: A0A1I8JCQ2 (PDZ domain-containing protein OS=Macrostomum lignano OX=282301 PE=4 SV=1)

HSP 1 Score: 109.768 bits (273), Expect = 8.352e-22
Identity = 95/301 (31.56%), Postives = 138/301 (45.85%), Query Frame = 2

Query:  326 MQTLNLRLTRDNLSRPWGFRLQGGSDTGYPLSVQRVFSGSPAEGILQRNDEIKIIDNSDVEHGTLKQVQDLIRTSGSQLNFIVVRDPNKEITNIDQSEEKISVQNA---RKMFASNENRSPQPFGQFGTEYH--------KKSNTLPTSLKIETNHEFYEQRN----------DTARHHEMNDEEDAADYSFMTLPVSERKKLFAKPDE-NLTTRSMPRQRSYSFRPSQKSNQIFPKTQSS--IYQRKPQEFGWAPSKEKFEKARN-----ALPNQSTVPLKYQANLAATP-TMGRSHPER 1138
            M  + +RL RD+L  PWGFR+QGG+D   PL+VQRVF+GSPAEG L R D +  IDN D       + QD+I+ SG  L  + +R P+  +     S    +V  A    ++ +    R   P  +FG +Y         ++    P   + +   + Y                A    M+D++   DY+F    V++R+K F +P     T  S+PR  S     S  +N+   K Q    + QR P EFGW PS +   +AR      A   QS +P + Q     +P   GRSH  R
Sbjct:    1 MAAVTVRLYRDSLQTPWGFRVQGGADFHTPLTVQRVFTGSPAEGELHRGDTVVGIDNYDATTMLHSEAQDVIKNSGGTL-LLNIRRPHGAVPPSQSSRAMAAVSAAPPHSRVPSQPTWRPSGPRPEFGVQYGGSPRGRAVQQPVMAPQHQQHQQQADNYMMDRVSRSLATMDLQAAAQRSMDDQD--VDYAFTQQSVADRRKAFMQPTSYGNTYHSVPRPNSSG---SAAANRYRQKRQPDPVLGQRVP-EFGWTPSPDLLRQARRGPSSAAFEQQSYLPSQGQGVREDSPFRAGRSHGGR 294

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BLAST of PDZ domain-containing protein vs. TrEMBL
Match: A0A267GMZ5 (PDZ domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig024866g1 PE=4 SV=1)

HSP 1 Score: 110.153 bits (274), Expect = 8.941e-22
Identity = 95/301 (31.56%), Postives = 138/301 (45.85%), Query Frame = 2

Query:  326 MQTLNLRLTRDNLSRPWGFRLQGGSDTGYPLSVQRVFSGSPAEGILQRNDEIKIIDNSDVEHGTLKQVQDLIRTSGSQLNFIVVRDPNKEITNIDQSEEKISVQNA---RKMFASNENRSPQPFGQFGTEYH--------KKSNTLPTSLKIETNHEFYEQRN----------DTARHHEMNDEEDAADYSFMTLPVSERKKLFAKPDE-NLTTRSMPRQRSYSFRPSQKSNQIFPKTQSS--IYQRKPQEFGWAPSKEKFEKARN-----ALPNQSTVPLKYQANLAATP-TMGRSHPER 1138
            M  + +RL RD+L  PWGFR+QGG+D   PL+VQRVF+GSPAEG L R D +  IDN D       + QD+I+ SG  L  + +R P+  +     S    +V  A    ++ +    R   P  +FG +Y         ++    P   + +   + Y                A    M+D++   DY+F    V++R+K F +P     T  S+PR  S     S  +N+   K Q    + QR P EFGW PS +   +AR      A   QS +P + Q     +P   GRSH  R
Sbjct:    1 MAAVTVRLYRDSLQTPWGFRVQGGADFHTPLTVQRVFTGSPAEGELHRGDTVVGIDNYDATTMLHSEAQDVIKNSGGTL-LLNIRRPHGAVPPSQSSRAMAAVSAAPPHSRVPSQPTWRPSGPRPEFGVQYGGSPRGRAVQQPVMAPQHQQHQQQADNYMMDRVSRSLATMDLQAAAQRSMDDQD--VDYAFTQQSVADRRKAFMQPTSYGNTYHSVPRPNSSG---SAAANRYRQKRQPDPVLGQRVP-EFGWTPSPDLLRQARRGPSSAAFEQQSYLPSQGQGVREDSPFRAGRSHGGR 294

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BLAST of PDZ domain-containing protein vs. TrEMBL
Match: A0A1I8GC93 (PDZ domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig024406g1 PE=4 SV=1)

HSP 1 Score: 109.768 bits (273), Expect = 1.209e-21
Identity = 95/301 (31.56%), Postives = 138/301 (45.85%), Query Frame = 2

Query:  326 MQTLNLRLTRDNLSRPWGFRLQGGSDTGYPLSVQRVFSGSPAEGILQRNDEIKIIDNSDVEHGTLKQVQDLIRTSGSQLNFIVVRDPNKEITNIDQSEEKISVQNA---RKMFASNENRSPQPFGQFGTEYH--------KKSNTLPTSLKIETNHEFYEQRN----------DTARHHEMNDEEDAADYSFMTLPVSERKKLFAKPDE-NLTTRSMPRQRSYSFRPSQKSNQIFPKTQSS--IYQRKPQEFGWAPSKEKFEKARN-----ALPNQSTVPLKYQANLAATP-TMGRSHPER 1138
            M  + +RL RD+L  PWGFR+QGG+D   PL+VQRVF+GSPAEG L R D +  IDN D       + QD+I+ SG  L  + +R P+  +     S    +V  A    ++ +    R   P  +FG +Y         ++    P   + +   + Y                A    M+D++   DY+F    V++R+K F +P     T  S+PR  S     S  +N+   K Q    + QR P EFGW PS +   +AR      A   QS +P + Q     +P   GRSH  R
Sbjct:    1 MAAVTVRLYRDSLQTPWGFRVQGGADFHTPLTVQRVFTGSPAEGELHRGDTVVGIDNYDATTMLHSEAQDVIKNSGGTL-LLNIRRPHGAVPPSQSSRAMAAVSAAPPHSRVPSQPTWRPSGPRPEFGVQYGGSPRGRAVQQPVMAPQHQQHQQQADNYMMDRVSRSLATMDLQAAAQRSMDDQD--VDYAFTQQSVADRRKAFMQPTSYGNTYHSVPRPNSSG---SAAANRYRQKRQPDPVLGQRVP-EFGWTPSPDLLRQARRGPSSAAFEQQSYLPSQGQGVREDSPFRAGRSHGGR 294

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BLAST of PDZ domain-containing protein vs. TrEMBL
Match: A0A1I8JD03 (PDZ domain-containing protein OS=Macrostomum lignano OX=282301 PE=4 SV=1)

HSP 1 Score: 110.153 bits (274), Expect = 1.656e-21
Identity = 95/301 (31.56%), Postives = 138/301 (45.85%), Query Frame = 2

Query:  326 MQTLNLRLTRDNLSRPWGFRLQGGSDTGYPLSVQRVFSGSPAEGILQRNDEIKIIDNSDVEHGTLKQVQDLIRTSGSQLNFIVVRDPNKEITNIDQSEEKISVQNA---RKMFASNENRSPQPFGQFGTEYH--------KKSNTLPTSLKIETNHEFYEQRN----------DTARHHEMNDEEDAADYSFMTLPVSERKKLFAKPDE-NLTTRSMPRQRSYSFRPSQKSNQIFPKTQSS--IYQRKPQEFGWAPSKEKFEKARN-----ALPNQSTVPLKYQANLAATP-TMGRSHPER 1138
            M  + +RL RD+L  PWGFR+QGG+D   PL+VQRVF+GSPAEG L R D +  IDN D       + QD+I+ SG  L  + +R P+  +     S    +V  A    ++ +    R   P  +FG +Y         ++    P   + +   + Y                A    M+D++   DY+F    V++R+K F +P     T  S+PR  S     S  +N+   K Q    + QR P EFGW PS +   +AR      A   QS +P + Q     +P   GRSH  R
Sbjct:    1 MAAVTVRLYRDSLQTPWGFRVQGGADFHTPLTVQRVFTGSPAEGELHRGDTVVGIDNYDATTMLHSEAQDVIKNSGGTL-LLNIRRPHGAVPPSQSSRAMAAVSAAPPHSRVPSQPTWRPSGPRPEFGVQYGGSPRGRAVQQPVMAPQHQQHQQQADNYMMDRVSRSLATMDLQAAAQRSMDDQD--VDYAFTQQSVADRRKAFMQPTSYGNTYHSVPRPNSSG---SAAANRYRQKRQPDPVLGQRVP-EFGWTPSPDLLRQARRGPSSAAFEQQSYLPSQGQGVREDSPFRAGRSHGGR 294

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BLAST of PDZ domain-containing protein vs. TrEMBL
Match: A0A1I8GEY9 (PDZ domain-containing protein OS=Macrostomum lignano OX=282301 PE=4 SV=1)

HSP 1 Score: 110.153 bits (274), Expect = 1.975e-21
Identity = 95/301 (31.56%), Postives = 138/301 (45.85%), Query Frame = 2

Query:  326 MQTLNLRLTRDNLSRPWGFRLQGGSDTGYPLSVQRVFSGSPAEGILQRNDEIKIIDNSDVEHGTLKQVQDLIRTSGSQLNFIVVRDPNKEITNIDQSEEKISVQNA---RKMFASNENRSPQPFGQFGTEYH--------KKSNTLPTSLKIETNHEFYEQRN----------DTARHHEMNDEEDAADYSFMTLPVSERKKLFAKPDE-NLTTRSMPRQRSYSFRPSQKSNQIFPKTQSS--IYQRKPQEFGWAPSKEKFEKARN-----ALPNQSTVPLKYQANLAATP-TMGRSHPER 1138
            M  + +RL RD+L  PWGFR+QGG+D   PL+VQRVF+GSPAEG L R D +  IDN D       + QD+I+ SG  L  + +R P+  +     S    +V  A    ++ +    R   P  +FG +Y         ++    P   + +   + Y                A    M+D++   DY+F    V++R+K F +P     T  S+PR  S     S  +N+   K Q    + QR P EFGW PS +   +AR      A   QS +P + Q     +P   GRSH  R
Sbjct:    1 MAAVTVRLYRDSLQTPWGFRVQGGADFHTPLTVQRVFTGSPAEGELHRGDTVVGIDNYDATTMLHSEAQDVIKNSGGTL-LLNIRRPHGAVPPSQSSRAMAAVSAAPPHSRVPSQPTWRPSGPRPEFGVQYGGSPRGRAVQQPVMAPQHQQHQQQADNYMMDRVSRSLATMDLQAAAQRSMDDQD--VDYAFTQQSVADRRKAFMQPTSYGNTYHSVPRPNSSG---SAAANRYRQKRQPDPVLGQRVP-EFGWTPSPDLLRQARRGPSSAAFEQQSYLPSQGQGVREDSPFRAGRSHGGR 294

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BLAST of PDZ domain-containing protein vs. Ensembl Cavefish
Match: ENSAMXT00000038897.1 (pep primary_assembly:Astyanax_mexicanus-2.0:25:9932529:9968599:-1 gene:ENSAMXG00000038221.1 transcript:ENSAMXT00000038897.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 51.6026 bits (122), Expect = 1.368e-6
Identity = 27/71 (38.03%), Postives = 38/71 (53.52%), Query Frame = 2

Query:  371 PWGFRLQGGSDTGYPLSVQRVFSGS-PAEGILQRNDEIKIIDNSDVEHGTLKQVQDLIRTSGSQLNFIVVR 580
            PWGFRLQGG D   PL++ R+  GS  A G L + D I  ID    +  T  + Q+ I+++   L   + R
Sbjct:   13 PWGFRLQGGKDFNMPLTISRITPGSKAAAGNLVQGDIIVAIDGVSTDGMTHLEAQNKIKSANFNLALTMTR 83

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BLAST of PDZ domain-containing protein vs. Ensembl Cavefish
Match: ENSAMXT00000049893.1 (pep primary_assembly:Astyanax_mexicanus-2.0:25:9951336:9975990:-1 gene:ENSAMXG00000038221.1 transcript:ENSAMXT00000049893.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 48.521 bits (114), Expect = 1.794e-6
Identity = 27/71 (38.03%), Postives = 38/71 (53.52%), Query Frame = 2

Query:  371 PWGFRLQGGSDTGYPLSVQRVFSGS-PAEGILQRNDEIKIIDNSDVEHGTLKQVQDLIRTSGSQLNFIVVR 580
            PWGFRLQGG D   PL++ R+  GS  A G L + D I  ID    +  T  + Q+ I+++   L   + R
Sbjct:   13 PWGFRLQGGKDFNMPLTISRITPGSKAAAGNLVQGDIIVAIDGVSTDGMTHLEAQNKIKSANFNLALTMTR 83

[Close]

BLAST of PDZ domain-containing protein vs. Ensembl Cavefish
Match: pdlim3b (PDZ and LIM domain protein 3 [Source:NCBI gene;Acc:103035000])

HSP 1 Score: 50.447 bits (119), Expect = 3.479e-6
Identity = 41/116 (35.34%), Postives = 54/116 (46.55%), Query Frame = 2

Query:  371 PWGFRLQGGSDTGYPLSVQRVFSGSPAEGI-LQRNDEIKIIDNSDVEHGTLKQVQDLIRTSGSQLNFIVVRDPNKEITNIDQSEE------KISV---QNARKMFASNENRSPQPF 688
            PWGFRL GG D   PL+V RV  GS A  + L   D I  I+    E  T  + Q+ I+ S  QL   + R P  ++ +    EE      KI++   Q   K   +  NR  QPF
Sbjct:   12 PWGFRLSGGKDFNQPLTVTRVTPGSKAALVNLTPGDVILAIEGVSTEGMTHGEAQNKIKDSTYQLCLKIER-PETKLWSPQVMEEGKTHPFKINLEAEQQEYKPIGTGHNRRAQPF 126

[Close]

BLAST of PDZ domain-containing protein vs. Ensembl Cavefish
Match: pdlim3b (PDZ and LIM domain protein 3 [Source:NCBI gene;Acc:103035000])

HSP 1 Score: 50.447 bits (119), Expect = 4.361e-6
Identity = 41/116 (35.34%), Postives = 54/116 (46.55%), Query Frame = 2

Query:  371 PWGFRLQGGSDTGYPLSVQRVFSGSPAEGI-LQRNDEIKIIDNSDVEHGTLKQVQDLIRTSGSQLNFIVVRDPNKEITNIDQSEE------KISV---QNARKMFASNENRSPQPF 688
            PWGFRL GG D   PL+V RV  GS A  + L   D I  I+    E  T  + Q+ I+ S  QL   + R P  ++ +    EE      KI++   Q   K   +  NR  QPF
Sbjct:   12 PWGFRLSGGKDFNQPLTVTRVTPGSKAALVNLTPGDVILAIEGVSTEGMTHGEAQNKIKDSTYQLCLKIER-PETKLWSPQVMEEGKTHPFKINLEAEQQEYKPIGTGHNRRAQPF 126

[Close]

BLAST of PDZ domain-containing protein vs. Ensembl Cavefish
Match: pdlim3a (PDZ and LIM domain protein 3-like [Source:NCBI gene;Acc:103042722])

HSP 1 Score: 50.0618 bits (118), Expect = 5.330e-6
Identity = 37/116 (31.90%), Postives = 56/116 (48.28%), Query Frame = 2

Query:  371 PWGFRLQGGSDTGYPLSVQRVFSGSPAEGI-LQRNDEIKIIDNSDVEHGTLKQVQDLIRTSGSQLNFIVVRDPNKEITNIDQSEE------KISVQNARKMF---ASNENRSPQPF 688
            PWGFRL GG D   PL++ R+ SGS A  + L   D I  ID     +      Q+ IR +  QL   + R P  ++ +   +E+      KI++++ R+ F    +  NR   PF
Sbjct:   12 PWGFRLIGGKDFNQPLTIARISSGSKASMVDLSPGDIILAIDGIATANMLHCDAQNHIREATDQLTLTIER-PEAQLWSPRVNEDGRAHPFKINLESERQEFRPIGTGHNRRAAPF 126

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BLAST of PDZ domain-containing protein vs. Ensembl Nematostella
Match: EDO30217 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T1F1])

HSP 1 Score: 46.2098 bits (108), Expect = 1.794e-6
Identity = 25/71 (35.21%), Postives = 40/71 (56.34%), Query Frame = 2

Query:  371 PWGFRLQGGSDTGYPLSVQRVFSGSPAE-GILQRNDEIKIIDNSDVEHGTLKQVQDLIRTSGSQLNFIVVR 580
            PWGFRLQGG D   PL + +V  GS AE   ++ N  ++ I+N   E  +     + I+ +G+ LN ++ +
Sbjct:   16 PWGFRLQGGKDFRAPLKIAKVEQGSKAERAGIRPNLYVRSINNDPCETMSHGDALNNIKRTGTNLNLLLCK 86

[Close]

BLAST of PDZ domain-containing protein vs. Ensembl Medaka
Match: pdlim4 (PDZ and LIM domain 4 [Source:NCBI gene;Acc:101166681])

HSP 1 Score: 56.225 bits (134), Expect = 4.900e-8
Identity = 32/77 (41.56%), Postives = 40/77 (51.95%), Query Frame = 2

Query:  371 PWGFRLQGGSDTGYPLSVQRVFSGS-PAEGILQRNDEIKIIDNSDVEHGTLKQVQDLIRTSGSQLNFIVVRDPNKEI 598
            PWGFRL GG D   PL+V RV  GS  A+G L   D I  I+    EH T  + Q+ I+T   QL   + R  N  +
Sbjct:   12 PWGFRLVGGRDFSTPLTVSRVTPGSKAAQGDLCPGDTILTINGDSTEHMTHMEAQNRIKTCTQQLTLSISRYGNGRL 88

[Close]

BLAST of PDZ domain-containing protein vs. Ensembl Medaka
Match: pdlim1 (PDZ and LIM domain 1 [Source:NCBI gene;Acc:101156764])

HSP 1 Score: 55.8398 bits (133), Expect = 6.820e-8
Identity = 40/119 (33.61%), Postives = 53/119 (44.54%), Query Frame = 2

Query:  371 PWGFRLQGGSDTGYPLSVQRVFSGS-PAEGILQRNDEIKIIDNSDVEHGTLKQVQDLIRTSGSQLNFIVVRDPNKEITNIDQSEEK--------ISVQNARKMFASNENRSPQPFGQFG 700
            PWGFRL GG D   PL++ RV +GS  A+  L   D I  ID    ++ T  + Q+ I+  G ++   V R   K  + +   E K         S     K   S  NRS  PF  FG
Sbjct:   12 PWGFRLVGGKDFEQPLAISRVNTGSKAAQANLCIGDIILAIDGEPTDNMTHLEAQNKIKACGDEMVLSVDRSEAKLWSPLSADEGKSHPYKMNLASEPREVKHIGSTHNRSALPFAGFG 130

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BLAST of PDZ domain-containing protein vs. Ensembl Medaka
Match: ldb3a (LIM domain-binding protein 3 [Source:NCBI gene;Acc:101165171])

HSP 1 Score: 55.4546 bits (132), Expect = 7.232e-8
Identity = 44/132 (33.33%), Postives = 57/132 (43.18%), Query Frame = 2

Query:  371 PWGFRLQGGSDTGYPLSVQRVFSGSPAE-GILQRNDEIKIIDNSDVEHGTLKQVQDLIRTSGSQLNFIVV---RDPNKEITNIDQSEEKISVQNARKMFASNENRSPQPFGQFGTEYHKKSNTLPTSLKIET 754
            PWGFRLQGG D   PL++ R+  GS A  G L + D I  ID    E  T  + Q+ I+ +   L   +    R P      ID     I  Q A  + A+N   +P   G        K NT+ T   IE 
Sbjct:   13 PWGFRLQGGKDFNMPLTISRITPGSKAALGNLIQGDVIVAIDGVSTEGMTHLEAQNKIKMANHSLALTMSKSKRPPPLAAPRIDSGISMIPHQQAFPLAATNAGFNP---GML------KENTISTHKAIEV 135

[Close]

BLAST of PDZ domain-containing protein vs. Ensembl Medaka
Match: ldb3a (LIM domain-binding protein 3 [Source:NCBI gene;Acc:101165171])

HSP 1 Score: 56.6102 bits (135), Expect = 8.328e-8
Identity = 44/132 (33.33%), Postives = 57/132 (43.18%), Query Frame = 2

Query:  371 PWGFRLQGGSDTGYPLSVQRVFSGSPAE-GILQRNDEIKIIDNSDVEHGTLKQVQDLIRTSGSQLNFIVV---RDPNKEITNIDQSEEKISVQNARKMFASNENRSPQPFGQFGTEYHKKSNTLPTSLKIET 754
            PWGFRLQGG D   PL++ R+  GS A  G L + D I  ID    E  T  + Q+ I+ +   L   +    R P      ID     I  Q A  + A+N   +P   G        K NT+ T   IE 
Sbjct:   13 PWGFRLQGGKDFNMPLTISRITPGSKAALGNLIQGDVIVAIDGVSTEGMTHLEAQNKIKMANHSLALTMSKSKRPPPLAAPRIDSGISMIPHQQAFPLAATNAGFNP---GML------KENTISTHKAIEV 135

[Close]

BLAST of PDZ domain-containing protein vs. Ensembl Medaka
Match: ldb3a (LIM domain-binding protein 3 [Source:NCBI gene;Acc:101165171])

HSP 1 Score: 56.6102 bits (135), Expect = 8.497e-8
Identity = 44/132 (33.33%), Postives = 57/132 (43.18%), Query Frame = 2

Query:  371 PWGFRLQGGSDTGYPLSVQRVFSGSPAE-GILQRNDEIKIIDNSDVEHGTLKQVQDLIRTSGSQLNFIVV---RDPNKEITNIDQSEEKISVQNARKMFASNENRSPQPFGQFGTEYHKKSNTLPTSLKIET 754
            PWGFRLQGG D   PL++ R+  GS A  G L + D I  ID    E  T  + Q+ I+ +   L   +    R P      ID     I  Q A  + A+N   +P   G        K NT+ T   IE 
Sbjct:   13 PWGFRLQGGKDFNMPLTISRITPGSKAALGNLIQGDVIVAIDGVSTEGMTHLEAQNKIKMANHSLALTMSKSKRPPPLAAPRIDSGISMIPHQQAFPLAATNAGFNP---GML------KENTISTHKAIEV 135

[Close]

BLAST of PDZ domain-containing protein vs. Planmine SMEST
Match: SMESG000023284.1 (SMESG000023284.1)

HSP 1 Score: 1088.56 bits (2814), Expect = 0.000e+0
Identity = 548/549 (99.82%), Postives = 548/549 (99.82%), Query Frame = 2

Query:  326 MQTLNLRLTRDNLSRPWGFRLQGGSDTGYPLSVQRVFSGSPAEGILQRNDEIKIIDNSDVEHGTLKQVQDLIRTSGSQLNFIVVRDPNKEITNIDQSEEKISVQNARKMFASNENRSPQPFGQFGTEYHKKSNTLPTSLKIETNHEFYEQRNDTARHHEMNDEEDAADYSFMTLPVSERKKLFAKPDENLTTRSMPRQRSYSFRPSQKSNQIFPKTQSSIYQRKPQEFGWAPSKEKFEKARNALPNQSTVPLKYQANLAATPTMGRSHPERIANNYYANXXXXXXXXXXXXXXXXXXMIPGQSRTPFTSSTLNFTPTSNERRQNIYPGERVKSQTKYIYHCGRNTNESSTEPSIIVIPASRQPQNLYVNTYGNQSLSPSQSPRFFRPAYPAYTTDHSAVDNMSIISVRSEPYSKRIDRSMAYDKPGTYRILRDSSSVQRDLSHDLGTLQIGEPRTRVIADPASPSCYLNRSFWGNEINNNRTHEQPIHSYVIESSPIRVDSKPFRRTPTVPKSQSTIVMNPSRPGNDSTYSQVSWLKQHRDSMAGISDF 1972
            MQTLNLRLTRDNLSRPWGFRLQGGSDTGYPLSVQRVFSGSPAEGILQRNDEIKIIDNSDVEHGTLKQVQDLIRTSGSQLNFIVVRDPNKEITNIDQSEEKISVQNARKMFASNENRSPQPFGQFGTEYHKKSNTLPTSLKIETNHEFYEQRNDTARHHEMNDEEDAADYSFMTLPVSERKKLFAKPDENLTTRSMPRQRSYSFRPSQKSNQIFPKTQSSIYQRKPQEFGWAPSKEKFEKARNALPNQSTVPLKYQANLAATPTMGRSHPERIANNYYANSQTTPRPSQPPRRFSSSTMIPGQSRTPFTSSTLNFTPTSNERRQNIYPGERVKSQTKYIYHCGRNTNESSTEPSIIVIPASRQPQNLYVNTYGNQSLSPSQSPRFFRPAYPAYTTDHSAVDNMSIISVRSEPYSKRIDRSMAYDKPGTYRILRDSSSVQRDLSHDLGTLQIGEPRTRVIADPASPSCYLNRSFWGNEINNNRTHEQPIHSYVIESSPIRVDSKPFRRTPTVPKSQSTIVMNPSRPGNDST SQVSWLKQHRDSMAGISDF
Sbjct:    1 MQTLNLRLTRDNLSRPWGFRLQGGSDTGYPLSVQRVFSGSPAEGILQRNDEIKIIDNSDVEHGTLKQVQDLIRTSGSQLNFIVVRDPNKEITNIDQSEEKISVQNARKMFASNENRSPQPFGQFGTEYHKKSNTLPTSLKIETNHEFYEQRNDTARHHEMNDEEDAADYSFMTLPVSERKKLFAKPDENLTTRSMPRQRSYSFRPSQKSNQIFPKTQSSIYQRKPQEFGWAPSKEKFEKARNALPNQSTVPLKYQANLAATPTMGRSHPERIANNYYANSQTTPRPSQPPRRFSSSTMIPGQSRTPFTSSTLNFTPTSNERRQNIYPGERVKSQTKYIYHCGRNTNESSTEPSIIVIPASRQPQNLYVNTYGNQSLSPSQSPRFFRPAYPAYTTDHSAVDNMSIISVRSEPYSKRIDRSMAYDKPGTYRILRDSSSVQRDLSHDLGTLQIGEPRTRVIADPASPSCYLNRSFWGNEINNNRTHEQPIHSYVIESSPIRVDSKPFRRTPTVPKSQSTIVMNPSRPGNDSTCSQVSWLKQHRDSMAGISDF 549

[Close]

BLAST of PDZ domain-containing protein vs. Planmine SMEST
Match: SMESG000064215.1 (SMESG000064215.1)

HSP 1 Score: 63.1586 bits (152), Expect = 2.725e-11
Identity = 32/86 (37.21%), Postives = 50/86 (58.14%), Query Frame = 2

Query:  323 NMQTLNLRLTRDNLSRPWGFRLQGGSDTGYPLSVQRVFSGSPAEGILQRNDEIKIIDNSDVEHGTLKQVQDLIRTSGSQLNFIVVR 580
            N ++L + L R++   PWGFR+QGG D    LSV++V SGSP++  LQ  D I  I+     +    +  +LI+ S  +L+ I+ R
Sbjct:   70 NTKSLEVILERNSEGEPWGFRIQGGHDYHLQLSVKKVKSGSPSDSKLQSGDAIIKINGFATHNLCHSEAIELIKCSSKKLSLIIAR 155

[Close]

BLAST of PDZ domain-containing protein vs. Planmine SMEST
Match: SMESG000015397.1 (SMESG000015397.1)

HSP 1 Score: 65.0846 bits (157), Expect = 3.456e-11
Identity = 36/91 (39.56%), Postives = 52/91 (57.14%), Query Frame = 2

Query:  329 QTLNLRLTRDNLSRPWGFRLQGGSDTGYPLSVQRVFSGSPAE-GILQRNDEIKIIDNSDVEHGTLKQVQDLIRTSGSQLNFIVVRDPNKEI 598
            QTL + L R + S PWGFRL+GG D G P+ + ++ SGS AE   LQ  D + +I+ S  E  T +Q +  I  S +++ F + R  N  I
Sbjct:    3 QTLIIDLRRSDTSIPWGFRLEGGVDMGAPIRIMKIVSGSIAEYAGLQPADYVLLINRSTTERMTHEQAKMEIIRSANEITFTISRGSNPPI 93

[Close]

BLAST of PDZ domain-containing protein vs. Planmine SMEST
Match: SMESG000029617.1 (SMESG000029617.1)

HSP 1 Score: 64.3142 bits (155), Expect = 9.418e-11
Identity = 35/98 (35.71%), Postives = 51/98 (52.04%), Query Frame = 2

Query:  326 MQTLNLRLTRDNLSRPWGFRLQGGSDTGYPLSVQRVFSGSPAEGI-LQRNDEIKIIDNSDVEHGTLKQVQDLIRTSGSQLNFIVVRDPNKEITNIDQS 616
            M+ +N  L++  L  PWGFR+QGG D   PL + R+   S A+   L+  D I  I+N D       + Q +I  SG+ LN  + RDP     N+ Q+
Sbjct:    1 MKQMNFNLSKAGLHNPWGFRIQGGRDFNRPLIISRITCDSVADNSGLKCGDRITKINNFDTGFICHNEAQQVIIESGNTLNLEITRDPLPVAENLKQT 98

[Close]

BLAST of PDZ domain-containing protein vs. Planmine SMEST
Match: SMESG000015639.1 (SMESG000015639.1)

HSP 1 Score: 57.3806 bits (137), Expect = 4.155e-9
Identity = 32/86 (37.21%), Postives = 50/86 (58.14%), Query Frame = 2

Query:  320 VNMQTLNLRLTRDNLSRPWGFRLQGGSDTGYPLSVQRVF-SGSPAEGILQRNDEIKIIDNSDVEHGTLKQVQDLIRTSGSQLNFIV 574
            +N++T+ L L R    +PWGF LQGGSD G P+ V +V  +G   +  L+  D I  I NS +   T  Q++  I  +G++++F V
Sbjct:    1 MNIETIVLSLRRTVTDKPWGFVLQGGSDQGLPVFVHKVTRNGIAHKSGLEPGDVIIQIGNSQLTGKTHAQIKAEILRAGNEIDFTV 86

The following BLAST results are available for this feature:

BLAST of PDZ domain-containing protein vs. Ensembl Human
BLAST of PDZ domain-containing protein vs. Ensembl Celegans
BLAST of PDZ domain-containing protein vs. Ensembl Fly
BLAST of PDZ domain-containing protein vs. Ensembl Zebrafish
BLAST of PDZ domain-containing protein vs. Ensembl Xenopus
BLAST of PDZ domain-containing protein vs. Ensembl Mouse
BLAST of PDZ domain-containing protein vs. UniProt/SwissProt
BLAST of PDZ domain-containing protein vs. TrEMBL
BLAST of PDZ domain-containing protein vs. Ensembl Cavefish
BLAST of PDZ domain-containing protein vs. Ensembl Sea Lamprey
BLAST of PDZ domain-containing protein vs. Ensembl Yeast
BLAST of PDZ domain-containing protein vs. Ensembl Nematostella
BLAST of PDZ domain-containing protein vs. Ensembl Medaka
BLAST of PDZ domain-containing protein vs. Planmine SMEST

BLAST of PDZ domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
PDLIM7	1.074e-6	30.91	PDZ and LIM domain 7 [Source:HGNC Symbol;Acc:HGNC:...	[more]
PDLIM7	1.575e-6	30.91	PDZ and LIM domain 7 [Source:HGNC Symbol;Acc:HGNC:...	[more]
PDLIM7	1.599e-6	30.91	PDZ and LIM domain 7 [Source:HGNC Symbol;Acc:HGNC:...	[more]
PDLIM3	2.096e-6	29.32	PDZ and LIM domain 3 [Source:HGNC Symbol;Acc:HGNC:...	[more]
PDLIM7	2.258e-6	30.91	PDZ and LIM domain 7 [Source:HGNC Symbol;Acc:HGNC:...	[more]

BLAST of PDZ domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of PDZ domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Zasp66	8.337e-11	38.37	gene:FBgn0035917 transcript:FBtr0089568	[more]
Zasp66	8.892e-11	38.37	gene:FBgn0035917 transcript:FBtr0301156	[more]
Zasp66	9.937e-11	38.37	gene:FBgn0035917 transcript:FBtr0301154	[more]
Zasp66	1.093e-10	38.37	gene:FBgn0035917 transcript:FBtr0089563	[more]
Zasp52	1.713e-9	42.17	gene:FBgn0265991 transcript:FBtr0329910	[more]

BLAST of PDZ domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ldb3b	6.324e-7	26.85	LIM domain binding 3b [Source:ZFIN;Acc:ZDB-GENE-03...	[more]
ldb3b	6.324e-7	26.85	LIM domain binding 3b [Source:ZFIN;Acc:ZDB-GENE-03...	[more]
ldb3b	6.324e-7	26.85	LIM domain binding 3b [Source:ZFIN;Acc:ZDB-GENE-03...	[more]
ldb3b	9.175e-7	38.03	LIM domain binding 3b [Source:ZFIN;Acc:ZDB-GENE-03...	[more]
ldb3b	1.344e-6	38.03	LIM domain binding 3b [Source:ZFIN;Acc:ZDB-GENE-03...	[more]

BLAST of PDZ domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 1


Match Name	E-value	Identity	Description
aldh4a1	6.959e-6	34.62	aldehyde dehydrogenase 4 family member A1 [Source:...	[more]

BLAST of PDZ domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Pdlim3	1.131e-6	29.32	PDZ and LIM domain 3 [Source:MGI Symbol;Acc:MGI:18...	[more]
Pdlim7	1.539e-6	26.67	PDZ and LIM domain 7 [Source:MGI Symbol;Acc:MGI:19...	[more]
Pdlim7	1.539e-6	26.67	PDZ and LIM domain 7 [Source:MGI Symbol;Acc:MGI:19...	[more]
Pdlim7	1.700e-6	26.32	PDZ and LIM domain 7 [Source:MGI Symbol;Acc:MGI:19...	[more]
Pdlim7	2.039e-6	30.91	PDZ and LIM domain 7 [Source:MGI Symbol;Acc:MGI:19...	[more]

BLAST of PDZ domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 3


Match Name	E-value	Identity	Description
sp\|A1ZA47\|ZASP_DROME	3.085e-8	42.17	PDZ and LIM domain protein Zasp OS=Drosophila mela...	[more]
sp\|Q3SYZ8\|PDLI3_BOVIN	4.433e-6	28.57	PDZ and LIM domain protein 3 OS=Bos taurus OX=9913...	[more]
sp\|O70209\|PDLI3_MOUSE	7.912e-6	29.32	PDZ and LIM domain protein 3 OS=Mus musculus OX=10...	[more]

BLAST of PDZ domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A1I8JCQ2	8.352e-22	31.56	PDZ domain-containing protein OS=Macrostomum ligna...	[more]
A0A267GMZ5	8.941e-22	31.56	PDZ domain-containing protein OS=Macrostomum ligna...	[more]
A0A1I8GC93	1.209e-21	31.56	PDZ domain-containing protein OS=Macrostomum ligna...	[more]
A0A1I8JD03	1.656e-21	31.56	PDZ domain-containing protein OS=Macrostomum ligna...	[more]
A0A1I8GEY9	1.975e-21	31.56	PDZ domain-containing protein OS=Macrostomum ligna...	[more]

BLAST of PDZ domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ENSAMXT00000038897.1	1.368e-6	38.03	pep primary_assembly:Astyanax_mexicanus-2.0:25:993...	[more]
ENSAMXT00000049893.1	1.794e-6	38.03	pep primary_assembly:Astyanax_mexicanus-2.0:25:995...	[more]
pdlim3b	3.479e-6	35.34	PDZ and LIM domain protein 3 [Source:NCBI gene;Acc...	[more]
pdlim3b	4.361e-6	35.34	PDZ and LIM domain protein 3 [Source:NCBI gene;Acc...	[more]
pdlim3a	5.330e-6	31.90	PDZ and LIM domain protein 3-like [Source:NCBI gen...	[more]

BLAST of PDZ domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of PDZ domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of PDZ domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1


Match Name	E-value	Identity	Description
EDO30217	1.794e-6	35.21	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of PDZ domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
pdlim4	4.900e-8	41.56	PDZ and LIM domain 4 [Source:NCBI gene;Acc:1011666...	[more]
pdlim1	6.820e-8	33.61	PDZ and LIM domain 1 [Source:NCBI gene;Acc:1011567...	[more]
ldb3a	7.232e-8	33.33	LIM domain-binding protein 3 [Source:NCBI gene;Acc...	[more]
ldb3a	8.328e-8	33.33	LIM domain-binding protein 3 [Source:NCBI gene;Acc...	[more]
ldb3a	8.497e-8	33.33	LIM domain-binding protein 3 [Source:NCBI gene;Acc...	[more]

BLAST of PDZ domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000023284.1	0.000e+0	99.82	SMESG000023284.1	[more]
SMESG000064215.1	2.725e-11	37.21	SMESG000064215.1	[more]
SMESG000015397.1	3.456e-11	39.56	SMESG000015397.1	[more]
SMESG000029617.1	9.418e-11	35.71	SMESG000029617.1	[more]
SMESG000015639.1	4.155e-9	37.21	SMESG000015639.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30017785 ID=SMED30017785|Name=PDZ domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=2257bp
CCGATCTGGGGGTGCGACGATATTTGTCGATTTTCTTCACTTGGGCACAG
AAAATTCGGGGGAAAATTGAACTTTCATAGTGTGCCTTCAGGTTTGTTGC
GACAATGTTTTCCGATGTGCAAAAATACCAATAGTAATGATGCTGTGAAA
CATTGATCGATTCGTAGAATTTACTGATCTGGGATTTATTGGGCAATGCT
GTGAGATCTGAGACAAATTTCCTTTCATTGGGGTACTACTGAAGTCTTCT
CAATTTTTGGTCCATATTCGTTGCTGTTGACGATAATTTGTATTCTTTTC
TTAGCATATTGCACCTCCAGTCAATATGCAGACACTCAATCTTCGTCTAA
CTAGGGATAATTTGAGTCGTCCCTGGGGATTTCGACTTCAAGGAGGATCT
GATACAGGGTATCCACTTTCAGTACAGCGGGTATTTTCGGGAAGTCCAGC
AGAAGGAATTTTACAAAGAAACGATGAAATAAAAATAATTGACAACTCTG
ATGTTGAACATGGAACTTTGAAACAAGTTCAAGACCTGATTCGGACCTCT
GGAAGCCAACTTAACTTTATTGTCGTGAGAGATCCAAATAAAGAAATAAC
CAATATAGACCAAAGTGAAGAAAAAATATCAGTTCAAAATGCTCGTAAAA
TGTTTGCAAGTAACGAAAACCGTTCACCTCAGCCGTTCGGACAGTTTGGA
ACCGAATATCATAAAAAGTCAAACACACTCCCAACAAGCCTTAAAATTGA
AACCAACCACGAATTCTATGAACAAAGAAACGATACAGCAAGACATCACG
AAATGAATGACGAGGAAGACGCGGCCGACTACAGCTTTATGACTTTGCCT
GTGAGCGAGCGGAAGAAATTATTCGCCAAACCCGACGAGAATTTAACAAC
TAGATCCATGCCTCGACAAAGATCATATAGCTTTCGACCATCTCAAAAAT
CTAACCAAATCTTTCCAAAAACTCAATCGTCGATTTATCAAAGAAAACCA
CAAGAATTTGGATGGGCTCCAAGTAAAGAGAAATTTGAAAAAGCGAGAAA
CGCCTTACCAAATCAGTCAACAGTTCCATTAAAATACCAAGCAAATCTCG
CTGCAACTCCTACAATGGGCAGATCACATCCAGAAAGGATAGCAAATAAT
TACTATGCCAATTCTCAAACTACTCCAAGACCTTCTCAACCCCCTCGTCG
TTTCAGTAGCAGTACAATGATACCAGGACAAAGTCGGACTCCGTTCACAT
CATCTACTTTGAATTTCACTCCAACTTCAAATGAACGTCGACAGAATATT
TATCCAGGAGAACGAGTTAAATCCCAAACGAAATACATATACCATTGCGG
TCGAAATACCAACGAGAGTTCTACGGAACCTTCTATCATTGTGATTCCTG
CAAGTAGACAGCCGCAAAACCTTTACGTCAATACATACGGGAACCAGTCA
TTATCGCCATCACAATCACCTCGGTTTTTCCGGCCAGCATATCCGGCGTA
TACCACGGACCACTCGGCGGTTGATAACATGTCCATAATTTCCGTACGGA
GTGAGCCTTATTCAAAACGCATAGACAGAAGTATGGCATACGATAAACCG
GGAACGTACAGAATCCTTCGAGACTCGAGTTCCGTACAGCGTGACTTGTC
ACACGACTTGGGCACCTTACAAATCGGTGAACCTCGGACTCGAGTCATTG
CTGATCCAGCCTCACCGAGTTGTTATCTGAACCGATCATTTTGGGGAAAT
GAAATCAACAACAATCGAACGCATGAGCAGCCGATTCACAGTTACGTAAT
CGAATCGAGTCCAATCAGAGTGGACTCAAAACCGTTTAGGAGAACACCGA
CAGTTCCCAAGTCTCAATCGACAATCGTCATGAATCCATCTCGACCCGGA
AACGATTCGACATATTCTCAAGTGTCTTGGTTGAAACAACACAGAGATAG
TATGGCCGGGATTTCAGATTTCTAGAAACTTTAGCTATTTTACTCCTTGA
TCTCAATTTTGATCGGTAATGCATGTTAATGAAAAACATTGAATTTCCTT
CCAAAAATGAAATCTCTAATATCTATGAGGACCCAGCAAAATTATTTCCT
ATTTTGCTTGCAGCTTGCTATCAAATTCACTTTATATGACATAGAGTCGG
TTGATGTTTTCGACTTATGGAAAAGTTCTAGATGAGATTATTAATAACGT
TTATAAACTACTCAATACCTACACCTCGTTCAAATATATTTTGGCATGAG
AAAAAAA

protein sequence of SMED30017785-orf-1

>SMED30017785-orf-1 ID=SMED30017785-orf-1|Name=SMED30017785-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=550bp
MQTLNLRLTRDNLSRPWGFRLQGGSDTGYPLSVQRVFSGSPAEGILQRND
EIKIIDNSDVEHGTLKQVQDLIRTSGSQLNFIVVRDPNKEITNIDQSEEK
ISVQNARKMFASNENRSPQPFGQFGTEYHKKSNTLPTSLKIETNHEFYEQ
RNDTARHHEMNDEEDAADYSFMTLPVSERKKLFAKPDENLTTRSMPRQRS
YSFRPSQKSNQIFPKTQSSIYQRKPQEFGWAPSKEKFEKARNALPNQSTV
PLKYQANLAATPTMGRSHPERIANNYYANSQTTPRPSQPPRRFSSSTMIP
GQSRTPFTSSTLNFTPTSNERRQNIYPGERVKSQTKYIYHCGRNTNESST
EPSIIVIPASRQPQNLYVNTYGNQSLSPSQSPRFFRPAYPAYTTDHSAVD
NMSIISVRSEPYSKRIDRSMAYDKPGTYRILRDSSSVQRDLSHDLGTLQI
GEPRTRVIADPASPSCYLNRSFWGNEINNNRTHEQPIHSYVIESSPIRVD
SKPFRRTPTVPKSQSTIVMNPSRPGNDSTYSQVSWLKQHRDSMAGISDF*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000101	muscle cell
PLANA:0000140	anterior region of the whole animal

Vocabulary: **INTERPRO**
Term	Definition
IPR036034	PDZ_sf
IPR001478	PDZ

Vocabulary: **molecular function**
Term	Definition
GO:0005515	protein binding
GO:0008270	zinc ion binding
GO:0042805	actinin binding
GO:0046872	metal ion binding

Vocabulary: **biological process**
Term	Definition
GO:0030036	actin cytoskeleton organization

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR001478	PDZ domain	SMART	SM00228	pdz_new	coord: 15..87 e-value: 2.1E-9 score: 47.3
IPR001478	PDZ domain	PFAM	PF00595	PDZ	coord: 11..81 e-value: 4.0E-8 score: 33.5
IPR001478	PDZ domain	PROSITE	PS50106	PDZ	coord: 5..87 score: 13.732
IPR036034	PDZ superfamily	GENE3D	G3DSA:2.30.42.10		coord: 8..101 e-value: 4.0E-17 score: 63.8
IPR036034	PDZ superfamily	SUPERFAMILY	SSF50156	PDZ domain-like	coord: 5..90
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 191..220
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 276..323
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 189..220
None	No IPR available	PANTHER	PTHR24214:SF38	FI06453P-RELATED	coord: 2..289
None	No IPR available	PANTHER	PTHR24214	FAMILY NOT NAMED	coord: 2..289
None	No IPR available	CDD	cd00992	PDZ_signaling	coord: 7..84 e-value: 1.22424E-15 score: 69.903

Main menu

PDZ domain-containing protein

Zeng et. al., 2018

▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 8

Owlery

blazegraph-runner