Peptidyl-glycine alpha-amidating monooxygenase

Overview
NamePeptidyl-glycine alpha-amidating monooxygenase
Smed IDSMED30017749
Length (bp)1524
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Peptidyl-glycine alpha-amidating monooxygenase (SMED30017749) t-SNE clustered cells

Violin plots show distribution of expression levels for Peptidyl-glycine alpha-amidating monooxygenase (SMED30017749) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Peptidyl-glycine alpha-amidating monooxygenase (SMED30017749) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Peptidyl-glycine alpha-amidating monooxygenase (SMED30017749) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30017749

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 12

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
head regionSMED30017749h1SMcG0015708 SmedASXL_010006SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016		whole organism asexual adult RNA-sequencing evidence
nervous systemSMED30017749h1SMcG0015708 dd_Smed_v4_3093_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30017749h1SMcG0015708 dd_Smed_v4_3093_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neuronSMED30017749h1SMcG0015708 dd_Smed_v4_3093_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		whole organism asexual adult colorimetric in situ hybridization evidence
non-ciliated neuronSMED30017749h1SMcG0015708 dd_Smed_v4_3093_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cilated neuronSMED30017749h1SMcG0015708 dd_Smed_v4_3093_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30017749h1SMcG0015708 Contig49495uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30017749h1SMcG0015708 Contig49495newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
head regionSMED30017749h1SMcG0015708 dd_Smed_v6_3093_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017		whole organism asexual adult RNA-sequencing evidence
head regionSMED30017749h1SMcG0015708 OX_Smed_1.0.08011ox_Smed_v2PMID:24238224
Kao et al., 2013		whole organism asexual adult RNA-sequencing evidence
neuronSMED30017749h1SMcG0015708 dd_Smed_v6_3093_0dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cholinergic neuronSMED30017749h1SMcG0015708 dd_Smed_v6_3093_0dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Peptidyl-glycine alpha-amidating monooxygenase vs. Ensembl Human
Match: PAM (peptidylglycine alpha-amidating monooxygenase [Source:HGNC Symbol;Acc:HGNC:8596])

HSP 1 Score: 177.563 bits (449), Expect = 7.003e-48
Identity = 117/296 (39.53%), Postives = 164/296 (55.41%), Query Frame = 3 
Query:  231 NWPSSKLLDYLGQVSGLSFCPKGYLYIFHRADVEMDERSFNNKNQYQKLSDGPIKESTXXXXXXXXXXAKVVGEFGSNLFYLPHGIFADKH-HMIATDLARHQVLRI-PHNSNKPDLILGEIFTPGNDANHFCKPTH-AVAAEDGTIFVADGYCNSRIVKFDKHGKFIGEFGNAKDKS-----RLSIPHHLVLIESKDLICAADRENMRVQCYSAGLKVTSKSGKLIKTIKDEKFGP-VYAVGFNKLNNLMYVVSDMVDDTDRSRV--FIYNWELDMVIGVMDYSGTNGFGMAHTI 1085
            +WP   LL   GQVSG++  PK  L IFHR D   D  SF++K  YQ++  GPI+E T   +  D +NA V+   G NLFYLPHG+  DK  +   TD+A HQV ++ P+N   P LILG    PG+D NHFC+PT  AV    G I+V+DGYCNSRIV+F   GKFI ++G     S     + ++PH L L+     +C ADREN R+QC+    K      + ++ IK   FG  V+A+ +  +  L++ V+      D+  V  F+ N+    +I +      + F M H I
Sbjct:  276 DWPGVYLLP--GQVSGVALDPKNNLVIFHRGDHVWDGNSFDSKFVYQQIGLGPIEEDT--ILVIDPNNAAVLQSSGKNLFYLPHGLSIDKDGNYWVTDVALHQVFKLDPNNKEGPVLILGRSMQPGSDQNHFCQPTDVAVDPGTGAIYVSDGYCNSRIVQFSPSGKFITQWGEESSGSSPLPGQFTVPHSLALVPLLGQLCVADRENGRIQCFKTDTK------EFVREIKHSSFGRNVFAISY--IPGLLFAVNGKPHFGDQEPVQGFVMNFSNGEIIDIFKPVRKH-FDMPHDI 558
[Close]
BLAST of Peptidyl-glycine alpha-amidating monooxygenase vs. Ensembl Human
Match: PAM (peptidylglycine alpha-amidating monooxygenase [Source:HGNC Symbol;Acc:HGNC:8596])

HSP 1 Score: 177.948 bits (450), Expect = 2.419e-47
Identity = 117/296 (39.53%), Postives = 164/296 (55.41%), Query Frame = 3 
Query:  231 NWPSSKLLDYLGQVSGLSFCPKGYLYIFHRADVEMDERSFNNKNQYQKLSDGPIKESTXXXXXXXXXXAKVVGEFGSNLFYLPHGIFADKH-HMIATDLARHQVLRI-PHNSNKPDLILGEIFTPGNDANHFCKPTH-AVAAEDGTIFVADGYCNSRIVKFDKHGKFIGEFGNAKDKS-----RLSIPHHLVLIESKDLICAADRENMRVQCYSAGLKVTSKSGKLIKTIKDEKFGP-VYAVGFNKLNNLMYVVSDMVDDTDRSRV--FIYNWELDMVIGVMDYSGTNGFGMAHTI 1085
            +WP   LL   GQVSG++  PK  L IFHR D   D  SF++K  YQ++  GPI+E T   +  D +NA V+   G NLFYLPHG+  DK  +   TD+A HQV ++ P+N   P LILG    PG+D NHFC+PT  AV    G I+V+DGYCNSRIV+F   GKFI ++G     S     + ++PH L L+     +C ADREN R+QC+    K      + ++ IK   FG  V+A+ +  +  L++ V+      D+  V  F+ N+    +I +      + F M H I
Sbjct:  503 DWPGVYLLP--GQVSGVALDPKNNLVIFHRGDHVWDGNSFDSKFVYQQIGLGPIEEDT--ILVIDPNNAAVLQSSGKNLFYLPHGLSIDKDGNYWVTDVALHQVFKLDPNNKEGPVLILGRSMQPGSDQNHFCQPTDVAVDPGTGAIYVSDGYCNSRIVQFSPSGKFITQWGEESSGSSPLPGQFTVPHSLALVPLLGQLCVADRENGRIQCFKTDTK------EFVREIKHSSFGRNVFAISY--IPGLLFAVNGKPHFGDQEPVQGFVMNFSNGEIIDIFKPVRKH-FDMPHDI 785
[Close]
BLAST of Peptidyl-glycine alpha-amidating monooxygenase vs. Ensembl Human
Match: PAM (peptidylglycine alpha-amidating monooxygenase [Source:HGNC Symbol;Acc:HGNC:8596])

HSP 1 Score: 177.563 bits (449), Expect = 2.455e-47
Identity = 117/296 (39.53%), Postives = 164/296 (55.41%), Query Frame = 3 
Query:  231 NWPSSKLLDYLGQVSGLSFCPKGYLYIFHRADVEMDERSFNNKNQYQKLSDGPIKESTXXXXXXXXXXAKVVGEFGSNLFYLPHGIFADKH-HMIATDLARHQVLRI-PHNSNKPDLILGEIFTPGNDANHFCKPTH-AVAAEDGTIFVADGYCNSRIVKFDKHGKFIGEFGNAKDKS-----RLSIPHHLVLIESKDLICAADRENMRVQCYSAGLKVTSKSGKLIKTIKDEKFGP-VYAVGFNKLNNLMYVVSDMVDDTDRSRV--FIYNWELDMVIGVMDYSGTNGFGMAHTI 1085
            +WP   LL   GQVSG++  PK  L IFHR D   D  SF++K  YQ++  GPI+E T   +  D +NA V+   G NLFYLPHG+  DK  +   TD+A HQV ++ P+N   P LILG    PG+D NHFC+PT  AV    G I+V+DGYCNSRIV+F   GKFI ++G     S     + ++PH L L+     +C ADREN R+QC+    K      + ++ IK   FG  V+A+ +  +  L++ V+      D+  V  F+ N+    +I +      + F M H I
Sbjct:  503 DWPGVYLLP--GQVSGVALDPKNNLVIFHRGDHVWDGNSFDSKFVYQQIGLGPIEEDT--ILVIDPNNAAVLQSSGKNLFYLPHGLSIDKDGNYWVTDVALHQVFKLDPNNKEGPVLILGRSMQPGSDQNHFCQPTDVAVDPGTGAIYVSDGYCNSRIVQFSPSGKFITQWGEESSGSSPLPGQFTVPHSLALVPLLGQLCVADRENGRIQCFKTDTK------EFVREIKHSSFGRNVFAISY--IPGLLFAVNGKPHFGDQEPVQGFVMNFSNGEIIDIFKPVRKH-FDMPHDI 785
[Close]
BLAST of Peptidyl-glycine alpha-amidating monooxygenase vs. Ensembl Human
Match: PAM (peptidylglycine alpha-amidating monooxygenase [Source:HGNC Symbol;Acc:HGNC:8596])

HSP 1 Score: 177.563 bits (449), Expect = 2.509e-47
Identity = 117/296 (39.53%), Postives = 164/296 (55.41%), Query Frame = 3 
Query:  231 NWPSSKLLDYLGQVSGLSFCPKGYLYIFHRADVEMDERSFNNKNQYQKLSDGPIKESTXXXXXXXXXXAKVVGEFGSNLFYLPHGIFADKH-HMIATDLARHQVLRI-PHNSNKPDLILGEIFTPGNDANHFCKPTH-AVAAEDGTIFVADGYCNSRIVKFDKHGKFIGEFGNAKDKS-----RLSIPHHLVLIESKDLICAADRENMRVQCYSAGLKVTSKSGKLIKTIKDEKFGP-VYAVGFNKLNNLMYVVSDMVDDTDRSRV--FIYNWELDMVIGVMDYSGTNGFGMAHTI 1085
            +WP   LL   GQVSG++  PK  L IFHR D   D  SF++K  YQ++  GPI+E T   +  D +NA V+   G NLFYLPHG+  DK  +   TD+A HQV ++ P+N   P LILG    PG+D NHFC+PT  AV    G I+V+DGYCNSRIV+F   GKFI ++G     S     + ++PH L L+     +C ADREN R+QC+    K      + ++ IK   FG  V+A+ +  +  L++ V+      D+  V  F+ N+    +I +      + F M H I
Sbjct:  396 DWPGVYLLP--GQVSGVALDPKNNLVIFHRGDHVWDGNSFDSKFVYQQIGLGPIEEDT--ILVIDPNNAAVLQSSGKNLFYLPHGLSIDKDGNYWVTDVALHQVFKLDPNNKEGPVLILGRSMQPGSDQNHFCQPTDVAVDPGTGAIYVSDGYCNSRIVQFSPSGKFITQWGEESSGSSPLPGQFTVPHSLALVPLLGQLCVADRENGRIQCFKTDTK------EFVREIKHSSFGRNVFAISY--IPGLLFAVNGKPHFGDQEPVQGFVMNFSNGEIIDIFKPVRKH-FDMPHDI 678
[Close]
BLAST of Peptidyl-glycine alpha-amidating monooxygenase vs. Ensembl Human
Match: PAM (peptidylglycine alpha-amidating monooxygenase [Source:HGNC Symbol;Acc:HGNC:8596])

HSP 1 Score: 177.948 bits (450), Expect = 2.565e-47
Identity = 117/296 (39.53%), Postives = 164/296 (55.41%), Query Frame = 3 
Query:  231 NWPSSKLLDYLGQVSGLSFCPKGYLYIFHRADVEMDERSFNNKNQYQKLSDGPIKESTXXXXXXXXXXAKVVGEFGSNLFYLPHGIFADKH-HMIATDLARHQVLRI-PHNSNKPDLILGEIFTPGNDANHFCKPTH-AVAAEDGTIFVADGYCNSRIVKFDKHGKFIGEFGNAKDKS-----RLSIPHHLVLIESKDLICAADRENMRVQCYSAGLKVTSKSGKLIKTIKDEKFGP-VYAVGFNKLNNLMYVVSDMVDDTDRSRV--FIYNWELDMVIGVMDYSGTNGFGMAHTI 1085
            +WP   LL   GQVSG++  PK  L IFHR D   D  SF++K  YQ++  GPI+E T   +  D +NA V+   G NLFYLPHG+  DK  +   TD+A HQV ++ P+N   P LILG    PG+D NHFC+PT  AV    G I+V+DGYCNSRIV+F   GKFI ++G     S     + ++PH L L+     +C ADREN R+QC+    K      + ++ IK   FG  V+A+ +  +  L++ V+      D+  V  F+ N+    +I +      + F M H I
Sbjct:  503 DWPGVYLLP--GQVSGVALDPKNNLVIFHRGDHVWDGNSFDSKFVYQQIGLGPIEEDT--ILVIDPNNAAVLQSSGKNLFYLPHGLSIDKDGNYWVTDVALHQVFKLDPNNKEGPVLILGRSMQPGSDQNHFCQPTDVAVDPGTGAIYVSDGYCNSRIVQFSPSGKFITQWGEESSGSSPLPGQFTVPHSLALVPLLGQLCVADRENGRIQCFKTDTK------EFVREIKHSSFGRNVFAISY--IPGLLFAVNGKPHFGDQEPVQGFVMNFSNGEIIDIFKPVRKH-FDMPHDI 785
[Close]
BLAST of Peptidyl-glycine alpha-amidating monooxygenase vs. Ensembl Celegans
Match: pgal-1 (Probable peptidyl-alpha-hydroxyglycine alpha-amidating lyase pgal-1 [Source:UniProtKB/Swiss-Prot;Acc:P91268])

HSP 1 Score: 170.244 bits (430), Expect = 3.804e-48
Identity = 99/230 (43.04%), Postives = 134/230 (58.26%), Query Frame = 3 
Query:  261 LGQVSGLSFCPKGYLYIFHRADVEMDERSFNNKNQYQKLSDGPIKESTXXXXXXXXXXAKVVGEFGSNLFYLPHGIFADKH-HMIATDLARHQVLRIPHNSNKPDLILGEIFTPGNDANHFCKPTHAVAAEDGTIFVADGYCNSRIVKFDKHGKFIGEFGNAKDK---SRLSIPHHLVLIESKDLICAADRENMRVQCYSAGLK---VTSKSGKLIKTIKDEKFGPVYAV 929
            +GQVSGL+    G++  FHR+    DE+SFN+   + K   G I   TI  I+ +    KV+ EFG+ LFY+PHG+  D +     TD+  HQV +I   + K  + LGE   PG D  HFCKPT    A++G IFVADGYCNSRI+KFD  G  + +   A ++   S   +PH L LIE  +++C ADREN RVQC+SAGL     T  +G  I +  D   G V+A+
Sbjct:   59 IGQVSGLAVNKNGHIVAFHRSGRVWDEKSFNDHETFNK-DLGVINNKTIAIISREK---KVIDEFGAGLFYMPHGLTIDNNGDYWVTDVGSHQVHKIDAKTQKIVMSLGEKMVPGEDQAHFCKPTDVAVAKNGHIFVADGYCNSRILKFDAKGNLMAQINAATEENQPSEFVVPHSLSLIEDMNIVCVADRENQRVQCFSAGLSEGDRTLPTGIPITSATD--IGRVFAI 282
[Close]
BLAST of Peptidyl-glycine alpha-amidating monooxygenase vs. Ensembl Celegans
Match: pgal-1 (Probable peptidyl-alpha-hydroxyglycine alpha-amidating lyase pgal-1 [Source:UniProtKB/Swiss-Prot;Acc:P91268])

HSP 1 Score: 170.244 bits (430), Expect = 3.804e-48
Identity = 99/230 (43.04%), Postives = 134/230 (58.26%), Query Frame = 3 
Query:  261 LGQVSGLSFCPKGYLYIFHRADVEMDERSFNNKNQYQKLSDGPIKESTXXXXXXXXXXAKVVGEFGSNLFYLPHGIFADKH-HMIATDLARHQVLRIPHNSNKPDLILGEIFTPGNDANHFCKPTHAVAAEDGTIFVADGYCNSRIVKFDKHGKFIGEFGNAKDK---SRLSIPHHLVLIESKDLICAADRENMRVQCYSAGLK---VTSKSGKLIKTIKDEKFGPVYAV 929
            +GQVSGL+    G++  FHR+    DE+SFN+   + K   G I   TI  I+ +    KV+ EFG+ LFY+PHG+  D +     TD+  HQV +I   + K  + LGE   PG D  HFCKPT    A++G IFVADGYCNSRI+KFD  G  + +   A ++   S   +PH L LIE  +++C ADREN RVQC+SAGL     T  +G  I +  D   G V+A+
Sbjct:   59 IGQVSGLAVNKNGHIVAFHRSGRVWDEKSFNDHETFNK-DLGVINNKTIAIISREK---KVIDEFGAGLFYMPHGLTIDNNGDYWVTDVGSHQVHKIDAKTQKIVMSLGEKMVPGEDQAHFCKPTDVAVAKNGHIFVADGYCNSRILKFDAKGNLMAQINAATEENQPSEFVVPHSLSLIEDMNIVCVADRENQRVQCFSAGLSEGDRTLPTGIPITSATD--IGRVFAI 282
[Close]
BLAST of Peptidyl-glycine alpha-amidating monooxygenase vs. Ensembl Celegans
Match: pamn-1 (Probable peptidyl-glycine alpha-amidating monooxygenase pamn-1 Probable peptidylglycine alpha-hydroxylating monooxygenase Probable peptidyl-alpha-hydroxyglycine alpha-amidating lyase [Source:UniProtKB/Swiss-Prot;Acc:P83388])

HSP 1 Score: 128.257 bits (321), Expect = 2.562e-31
Identity = 99/309 (32.04%), Postives = 154/309 (49.84%), Query Frame = 3 
Query:  261 LGQVSGLSFCPKGYLYIFHRADVEMDERSFNNKNQYQKLSDGPIKESTXXXXXXXXXXAKVVGEFGSNLFYLPHGIFADKHHMI-ATDLARHQV--LRIPHNSNKPDLILGEIFTPGNDANHFCKPTHAVAAEDGTIFVADGYCNSRIVKFDKHGKFIGEFG-NAKDKSRLSIPHHLVLIESKDLICAADRENMRVQCYSAGLKVTSKSGKLIKTIKDEKFGPVYAVGFNKLNNLMYVVSD---MVDDTDRSRVFIYNWELDMVIGVMDYS---GTNG--------FGMAHTIDVCPRGHCVAIGSLTK 1133
            LGQV+GL+F  +  L +F RA    D  +F+N N    L   PI +  I+ I+   +  K+  + G   FYLPHGI+ DK   +  TD+  H V   +I  N  K     GE+  PG+D +H+CKPT     ED  ++V DGYCNSR+V  D +GK I +FG   +D  + ++PH +V  +S   +   DREN RVQ         +  G +I+  K   F  +Y+   ++  + +++V     M  +T+   VF+         G+++Y+    T G        FG  H + VCP G  + +G + +
Sbjct:  357 LGQVAGLAFNNEQQLLVFQRAGRVWDASTFDNYNIL--LDKKPIADPVILVISYSGNQTKLERKLGGGQFYLPHGIYVDKDGFVYTTDVGSHTVAKWKIEGNELKNIWTSGELLMPGSDQHHYCKPTGITRVED-QLYVTDGYCNSRVVVLDLNGKRIRQFGLPGEDAGQFNLPHDIV-SDSAGRLLVTDRENGRVQH-------MTTQGHVIEEFKSTMFTNIYSAASHE--DYVFMVPGRPIMGHETEGIAVFVGR----SGTGLIEYAFGPTTKGKREQMGPQFGQPHCLRVCPDGGHIFVGDIAE 648
[Close]
BLAST of Peptidyl-glycine alpha-amidating monooxygenase vs. Ensembl Fly
Match: Pal2 (gene:FBgn0262728 transcript:FBtr0089500)

HSP 1 Score: 185.267 bits (469), Expect = 3.996e-53
Identity = 98/238 (41.18%), Postives = 135/238 (56.72%), Query Frame = 3 
Query:  222 LVPNWPSSKLLDYLGQVSGLSFCPKGYLYIFHRADVEMDERSFNNKNQYQKLSDGPIKESTXXXXXXXXXXAKVVGEFGSNLFYLPHGIFADKH-HMIATDLARHQVLRIPHNSNKPDLILGEIFTPGNDANHFCKPTHAVAAEDGTIFVADGYCNSRIVKFDKHGKFIGEFGNAKDKSRLSIPHHLVLIESKDLICAADRENMRVQCYSAGLKVTSKSGKLIKTIKDEKFGPVYAVG 932
            LV NWP+ +     GQV+ ++  P+G   +FHRA+   D  +FN  N Y  +  GPIKE+TI  ++      K    +GSN+FY+PHG+  D H +   TD+A HQ  +    SNKP L +G+ F PG+   H CKPT    A  G  F+ADGYCNSRI+KF+  GK +       +   L +PH + L+E  DL+C ADRENMRV C  AGL  +   G+   TI++   G V+ V 
Sbjct:  101 LVENWPTEQ--HSFGQVTAVAVDPQGSPVVFHRAERYWDVNTFNESNIYYLIEYGPIKENTIYVLDAKTGAIK--SGWGSNMFYMPHGLTIDLHGNYWITDVAMHQAFKFKPFSNKPLLTIGKRFRPGSSVKHLCKPTSIAVATTGEFFIADGYCNSRILKFNAAGKLLRTIPQPPEFLSLQVPHAITLLEHLDLLCIADRENMRVVCPKAGLISSHGEGEPAATIQEPDLGRVFGVA 334
[Close]
BLAST of Peptidyl-glycine alpha-amidating monooxygenase vs. Ensembl Fly
Match: Pal2 (gene:FBgn0262728 transcript:FBtr0346652)

HSP 1 Score: 185.267 bits (469), Expect = 3.996e-53
Identity = 98/238 (41.18%), Postives = 135/238 (56.72%), Query Frame = 3 
Query:  222 LVPNWPSSKLLDYLGQVSGLSFCPKGYLYIFHRADVEMDERSFNNKNQYQKLSDGPIKESTXXXXXXXXXXAKVVGEFGSNLFYLPHGIFADKH-HMIATDLARHQVLRIPHNSNKPDLILGEIFTPGNDANHFCKPTHAVAAEDGTIFVADGYCNSRIVKFDKHGKFIGEFGNAKDKSRLSIPHHLVLIESKDLICAADRENMRVQCYSAGLKVTSKSGKLIKTIKDEKFGPVYAVG 932
            LV NWP+ +     GQV+ ++  P+G   +FHRA+   D  +FN  N Y  +  GPIKE+TI  ++      K    +GSN+FY+PHG+  D H +   TD+A HQ  +    SNKP L +G+ F PG+   H CKPT    A  G  F+ADGYCNSRI+KF+  GK +       +   L +PH + L+E  DL+C ADRENMRV C  AGL  +   G+   TI++   G V+ V 
Sbjct:  101 LVENWPTEQ--HSFGQVTAVAVDPQGSPVVFHRAERYWDVNTFNESNIYYLIEYGPIKENTIYVLDAKTGAIK--SGWGSNMFYMPHGLTIDLHGNYWITDVAMHQAFKFKPFSNKPLLTIGKRFRPGSSVKHLCKPTSIAVATTGEFFIADGYCNSRILKFNAAGKLLRTIPQPPEFLSLQVPHAITLLEHLDLLCIADRENMRVVCPKAGLISSHGEGEPAATIQEPDLGRVFGVA 334
[Close]
BLAST of Peptidyl-glycine alpha-amidating monooxygenase vs. Ensembl Fly
Match: Pal2 (gene:FBgn0262728 transcript:FBtr0301509)

HSP 1 Score: 185.267 bits (469), Expect = 3.996e-53
Identity = 98/238 (41.18%), Postives = 135/238 (56.72%), Query Frame = 3 
Query:  222 LVPNWPSSKLLDYLGQVSGLSFCPKGYLYIFHRADVEMDERSFNNKNQYQKLSDGPIKESTXXXXXXXXXXAKVVGEFGSNLFYLPHGIFADKH-HMIATDLARHQVLRIPHNSNKPDLILGEIFTPGNDANHFCKPTHAVAAEDGTIFVADGYCNSRIVKFDKHGKFIGEFGNAKDKSRLSIPHHLVLIESKDLICAADRENMRVQCYSAGLKVTSKSGKLIKTIKDEKFGPVYAVG 932
            LV NWP+ +     GQV+ ++  P+G   +FHRA+   D  +FN  N Y  +  GPIKE+TI  ++      K    +GSN+FY+PHG+  D H +   TD+A HQ  +    SNKP L +G+ F PG+   H CKPT    A  G  F+ADGYCNSRI+KF+  GK +       +   L +PH + L+E  DL+C ADRENMRV C  AGL  +   G+   TI++   G V+ V 
Sbjct:  101 LVENWPTEQ--HSFGQVTAVAVDPQGSPVVFHRAERYWDVNTFNESNIYYLIEYGPIKENTIYVLDAKTGAIK--SGWGSNMFYMPHGLTIDLHGNYWITDVAMHQAFKFKPFSNKPLLTIGKRFRPGSSVKHLCKPTSIAVATTGEFFIADGYCNSRILKFNAAGKLLRTIPQPPEFLSLQVPHAITLLEHLDLLCIADRENMRVVCPKAGLISSHGEGEPAATIQEPDLGRVFGVA 334
[Close]
BLAST of Peptidyl-glycine alpha-amidating monooxygenase vs. Ensembl Fly
Match: Pal1 (gene:FBgn0283510 transcript:FBtr0339422)

HSP 1 Score: 159.844 bits (403), Expect = 9.568e-43
Identity = 87/216 (40.28%), Postives = 128/216 (59.26%), Query Frame = 3 
Query:  234 WPSSKLLDYLGQVSGLSFCPKGYLYIFHRADVEMDERSFNNKNQYQKLSDGPIKESTXXXXXXXXXXAKVVGEFGSNLFYLPHGIFAD-KHHMIATDLARHQVLRIPHNSN--KPDLILGEIFTPGNDANHFCKPTHAVAAEDGTIFVADGYCNSRIVKFDKHGKFIGEFG---------NAKDKSRLSIPHHLVLIESKDLICAADRENMRVQCY 845
            WP++ +   LG V+ +SF   G + IFHR +    + +F+N+NQYQ+   GPI+ESTI+ +       KV  ++G N FY+PHG+  D + ++  TD+A HQV + P      KP L LG+ F PG+    FCKPT     ++G  FVADGYCN+RI+K+ + G+ I  +G         +   ++  +IPH L L+    L+CAADREN RVQC+
Sbjct:  101 WPANNV--KLGAVTAVSFDKAGNVVIFHRVNRVWGQTTFDNRNQYQEKYRGPIRESTILALEPAT--GKVQYDWGKNFFYMPHGLTVDPEDNVWLTDVAMHQVFKFPPRGGDGKPALTLGDAFQPGS-GRKFCKPTSVAVLDNGDFFVADGYCNARILKYSRKGELILFWGQNTFSGISYDVAPQNFFAIPHALTLVPELQLLCAADRENGRVQCF 311
[Close]
BLAST of Peptidyl-glycine alpha-amidating monooxygenase vs. Ensembl Fly
Match: Pal1 (gene:FBgn0283510 transcript:FBtr0339423)

HSP 1 Score: 159.073 bits (401), Expect = 2.264e-42
Identity = 87/216 (40.28%), Postives = 128/216 (59.26%), Query Frame = 3 
Query:  234 WPSSKLLDYLGQVSGLSFCPKGYLYIFHRADVEMDERSFNNKNQYQKLSDGPIKESTXXXXXXXXXXAKVVGEFGSNLFYLPHGIFAD-KHHMIATDLARHQVLRIPHNSN--KPDLILGEIFTPGNDANHFCKPTHAVAAEDGTIFVADGYCNSRIVKFDKHGKFIGEFG---------NAKDKSRLSIPHHLVLIESKDLICAADRENMRVQCY 845
            WP++ +   LG V+ +SF   G + IFHR +    + +F+N+NQYQ+   GPI+ESTI+ +       KV  ++G N FY+PHG+  D + ++  TD+A HQV + P      KP L LG+ F PG+    FCKPT     ++G  FVADGYCN+RI+K+ + G+ I  +G         +   ++  +IPH L L+    L+CAADREN RVQC+
Sbjct:  101 WPANNV--KLGAVTAVSFDKAGNVVIFHRVNRVWGQTTFDNRNQYQEKYRGPIRESTILALEPAT--GKVQYDWGKNFFYMPHGLTVDPEDNVWLTDVAMHQVFKFPPRGGDGKPALTLGDAFQPGS-GRKFCKPTSVAVLDNGDFFVADGYCNARILKYSRKGELILFWGQNTFSGISYDVAPQNFFAIPHALTLVPELQLLCAADRENGRVQCF 311
[Close]
BLAST of Peptidyl-glycine alpha-amidating monooxygenase vs. Ensembl Zebrafish
Match: pam (peptidylglycine alpha-amidating monooxygenase [Source:ZFIN;Acc:ZDB-GENE-090313-384])

HSP 1 Score: 170.629 bits (431), Expect = 5.454e-46
Identity = 105/256 (41.02%), Postives = 148/256 (57.81%), Query Frame = 3 
Query:  225 VPNWPSSKLLDYLGQVSGLSFCPKGYLYIFHRADVEMDERSFNNKNQYQKLSDGPIKESTXXXXXXXXXXAKVVGEFGSNLFYLPHGIFAD-KHHMIATDLARHQVLRIPHNS-NKPDLILGEIFTPGNDANHFCKPTH-AVAAEDGTIFVADGYCNSRIVKFDKHGKFIGEFG-NAKDKSR---LSIPHHLVLIESKDLICAADRENMRVQCYSAGLKVTSKSGKLIKTIKDEKF-GPVYAVGFNKLN-NLMYVV 965
            V +WP + L   LGQVSGL+    G L IFHR D      SFN    YQ    GPI++STI+ +++     KV+   G N+FYLPHGI  D   +   TD+A HQV ++  N  ++  L+LGE F PG+D  HFC+PT  AV    G ++V+DGYCNSRI++F   GK+I  +G  + D+ R     IPH L  +  K  +C ADR+N R+QC+ A       +G+ +K IK + F G V+A+ ++     L+Y V
Sbjct:   83 VSDWPEADL--QLGQVSGLALNSNGDLVIFHRGDHIWGIDSFNMNAIYQLRDQGPIQQSTILLVDSVK--GKVLKASGKNMFYLPHGITTDHDDNYWVTDVALHQVFKLSGNGKDQQLLVLGEAFEPGSDKKHFCQPTDVAVDPVTGNVYVSDGYCNSRILQFSPEGKYISHWGAGSSDRKRRVPFRIPHSLTFLPDKRELCVADRDNGRIQCFMA------DTGEFVKEIKKDVFGGEVFAIAYSPAQGGLLYAV 328
[Close]
BLAST of Peptidyl-glycine alpha-amidating monooxygenase vs. Ensembl Zebrafish
Match: pam (peptidylglycine alpha-amidating monooxygenase [Source:ZFIN;Acc:ZDB-GENE-090313-384])

HSP 1 Score: 170.629 bits (431), Expect = 1.397e-45
Identity = 105/256 (41.02%), Postives = 148/256 (57.81%), Query Frame = 3 
Query:  225 VPNWPSSKLLDYLGQVSGLSFCPKGYLYIFHRADVEMDERSFNNKNQYQKLSDGPIKESTXXXXXXXXXXAKVVGEFGSNLFYLPHGIFAD-KHHMIATDLARHQVLRIPHN-SNKPDLILGEIFTPGNDANHFCKPTH-AVAAEDGTIFVADGYCNSRIVKFDKHGKFIGEFG-NAKDKSR---LSIPHHLVLIESKDLICAADRENMRVQCYSAGLKVTSKSGKLIKTIKDEKF-GPVYAVGFNKLN-NLMYVV 965
            V +WP + L   LGQVSGL+    G L IFHR D      SFN    YQ    GPI++STI+ +++     KV+   G N+FYLPHGI  D   +   TD+A HQV ++  N  ++  L+LGE F PG+D  HFC+PT  AV    G ++V+DGYCNSRI++F   GK+I  +G  + D+ R     IPH L  +  K  +C ADR+N R+QC+ A       +G+ +K IK + F G V+A+ ++     L+Y V
Sbjct:  184 VSDWPEADL--QLGQVSGLALNSNGDLVIFHRGDHIWGIDSFNMNAIYQLRDQGPIQQSTILLVDSVK--GKVLKASGKNMFYLPHGITTDHDDNYWVTDVALHQVFKLSGNGKDQQLLVLGEAFEPGSDKKHFCQPTDVAVDPVTGNVYVSDGYCNSRILQFSPEGKYISHWGAGSSDRKRRVPFRIPHSLTFLPDKRELCVADRDNGRIQCFMA------DTGEFVKEIKKDVFGGEVFAIAYSPAQGGLLYAV 429
[Close]
BLAST of Peptidyl-glycine alpha-amidating monooxygenase vs. Ensembl Zebrafish
Match: pam (peptidylglycine alpha-amidating monooxygenase [Source:ZFIN;Acc:ZDB-GENE-090313-384])

HSP 1 Score: 171.014 bits (432), Expect = 4.405e-45
Identity = 107/263 (40.68%), Postives = 149/263 (56.65%), Query Frame = 3 
Query:  225 VPNWPSSKLLDYLGQVSGLSFCPKGYLYIFHRADVEMDERSFNNKNQYQKLSDGPIKESTXXXXXXXXXXAKVVGEFGSNLFYLPHGIFADKH-HMIATDLARHQVLRIPHNS-NKPDLILGEIFTPGNDANHFCKPTH-AVAAEDGTIFVADGYCNSRIVKFDKHGKFIGEFGNAKDKSRLS-----------IPHHLVLIESKDLICAADRENMRVQCYSAGLKVTSKSGKLIKTIKDEKF-GPVYAVGFNKLN-NLMYVV 965
            V +WP + L   LGQVSGL+    G L IFHR D      SFN    YQ    GPI++STI+ +++     KV+   G N+FYLPHGI  D   +   TD+A HQV ++  N  ++  L+LGE F PG+D  HFC+PT  AV    G ++V+DGYCNSRI++F   GK+I  +G  + KS LS           IPH L  +  K  +C ADR+N R+QC+ A       +G+ +K IK + F G V+A+ ++     L+Y V
Sbjct:  495 VSDWPEADL--QLGQVSGLALNSNGDLVIFHRGDHIWGIDSFNMNAIYQLRDQGPIQQSTILLVDSVK--GKVLKASGKNMFYLPHGITTDHDDNYWVTDVALHQVFKLSGNGKDQQLLVLGEAFEPGSDKKHFCQPTDVAVDPVTGNVYVSDGYCNSRILQFSPEGKYISHWGADQRKSALSSALPGRRVPFRIPHSLTFLPDKRELCVADRDNGRIQCFMA------DTGEFVKEIKKDVFGGEVFAIAYSPAQGGLLYAV 747
[Close]
BLAST of Peptidyl-glycine alpha-amidating monooxygenase vs. Ensembl Zebrafish
Match: pam (peptidylglycine alpha-amidating monooxygenase [Source:ZFIN;Acc:ZDB-GENE-090313-384])

HSP 1 Score: 70.0922 bits (170), Expect = 2.643e-12
Identity = 47/106 (44.34%), Postives = 57/106 (53.77%), Query Frame = 3 
Query:  225 VPNWPSSKLLDYLGQVSGLSFCPKGYLYIFHRADVEMDERSFNNKNQYQKLSDGPIKESTXXXXXXXXXXAKVVGEFGSNLFYLPHGIFAD-KHHMIATDLARHQV 539
            V +WP + L   LGQVSGL+    G L IFHR D      SFN    YQ    GPI++ST   +  D    KV+   G N+FYLPHGI  D   +   TD+A HQV
Sbjct:  394 VSDWPEADL--QLGQVSGLALNSNGDLVIFHRGDHIWGIDSFNMNAIYQLRDQGPIQQST--ILLVDSVKGKVLKASGKNMFYLPHGITTDHDDNYWVTDVALHQV 495
[Close]
BLAST of Peptidyl-glycine alpha-amidating monooxygenase vs. Ensembl Xenopus
Match: pam (peptidylglycine alpha-amidating monooxygenase [Source:NCBI gene;Acc:100170159])

HSP 1 Score: 179.489 bits (454), Expect = 6.785e-48
Identity = 114/287 (39.72%), Postives = 160/287 (55.75%), Query Frame = 3 
Query:  135 NELNQLQKS-PVGKVAVENKPF-KVTLENANLVPNWPSSKLLDYLGQVSGLSFCPKGYLYIFHRADVEMDERSFNNKNQYQKLSDGPIKESTXXXXXXXXXXAKVVGEFGSNLFYLPHGIFADKH-HMIATDLARHQVLRIPHNSNKPDLILGEIFTPGNDANHFCKPTH-AVAAEDGTIFVADGYCNSRIVKFDKHGKFIGEFGNAKDKS-----RLSIPHHLVLIESKDLICAADRENMRVQCYSAGLKVTSKSGKLIKTIKDEKFG-PVYAVGFNKLNNLMYVV 965
            N L Q+Q+  P G    E +    V LE      +WP   L   +GQVSGL+  PK  L IFHR D   DE SF+    YQ+   GPI+EST   +  D + +KV+   G NLF+LPHG+  D+  +   TD+A HQV ++      P L+LG+ F PG+D  HFC+PT  AV    G  FV+DGYCNSRI++F  +G FI ++G+    +     +  IPH L ++     +C ADREN R+QC+ A      ++GK +K IK  +FG  V+AV +     ++Y V
Sbjct:  438 NTLPQVQQGRPAGADTREKQHLGDVHLEEDT---DWPGVNL--KVGQVSGLALDPKNNLVIFHRGDHVWDENSFDRNFVYQQRGIGPIQEST--ILVVDPNTSKVLKSAGKNLFFLPHGLTIDRDGNYWVTDVALHQVFKLGAEKETPLLVLGKAFQPGSDRKHFCQPTDVAVDPITGNFFVSDGYCNSRIMQFSPNGMFIMQWGDETSSTIPKPGQFRIPHSLTMVPDHGQLCVADRENGRIQCFHA------ETGKFVKQIKHREFGREVFAVSYAP-GGVLYAV 710
[Close]
BLAST of Peptidyl-glycine alpha-amidating monooxygenase vs. Ensembl Xenopus
Match: pam (peptidylglycine alpha-amidating monooxygenase [Source:NCBI gene;Acc:100170159])

HSP 1 Score: 179.489 bits (454), Expect = 6.823e-48
Identity = 114/287 (39.72%), Postives = 160/287 (55.75%), Query Frame = 3 
Query:  135 NELNQLQKS-PVGKVAVENKPF-KVTLENANLVPNWPSSKLLDYLGQVSGLSFCPKGYLYIFHRADVEMDERSFNNKNQYQKLSDGPIKESTXXXXXXXXXXAKVVGEFGSNLFYLPHGIFADKH-HMIATDLARHQVLRIPHNSNKPDLILGEIFTPGNDANHFCKPTH-AVAAEDGTIFVADGYCNSRIVKFDKHGKFIGEFGNAKDKS-----RLSIPHHLVLIESKDLICAADRENMRVQCYSAGLKVTSKSGKLIKTIKDEKFG-PVYAVGFNKLNNLMYVV 965
            N L Q+Q+  P G    E +    V LE      +WP   L   +GQVSGL+  PK  L IFHR D   DE SF+    YQ+   GPI+EST   +  D + +KV+   G NLF+LPHG+  D+  +   TD+A HQV ++      P L+LG+ F PG+D  HFC+PT  AV    G  FV+DGYCNSRI++F  +G FI ++G+    +     +  IPH L ++     +C ADREN R+QC+ A      ++GK +K IK  +FG  V+AV +     ++Y V
Sbjct:  459 NTLPQVQQGRPAGADTREKQHLGDVHLEEDT---DWPGVNL--KVGQVSGLALDPKNNLVIFHRGDHVWDENSFDRNFVYQQRGIGPIQEST--ILVVDPNTSKVLKSAGKNLFFLPHGLTIDRDGNYWVTDVALHQVFKLGAEKETPLLVLGKAFQPGSDRKHFCQPTDVAVDPITGNFFVSDGYCNSRIMQFSPNGMFIMQWGDETSSTIPKPGQFRIPHSLTMVPDHGQLCVADRENGRIQCFHA------ETGKFVKQIKHREFGREVFAVSYAP-GGVLYAV 731
[Close]
BLAST of Peptidyl-glycine alpha-amidating monooxygenase vs. Ensembl Xenopus
Match: pam (peptidylglycine alpha-amidating monooxygenase [Source:NCBI gene;Acc:100170159])

HSP 1 Score: 179.489 bits (454), Expect = 6.873e-48
Identity = 114/287 (39.72%), Postives = 160/287 (55.75%), Query Frame = 3 
Query:  135 NELNQLQKS-PVGKVAVENKPF-KVTLENANLVPNWPSSKLLDYLGQVSGLSFCPKGYLYIFHRADVEMDERSFNNKNQYQKLSDGPIKESTXXXXXXXXXXAKVVGEFGSNLFYLPHGIFADKH-HMIATDLARHQVLRIPHNSNKPDLILGEIFTPGNDANHFCKPTH-AVAAEDGTIFVADGYCNSRIVKFDKHGKFIGEFGNAKDKS-----RLSIPHHLVLIESKDLICAADRENMRVQCYSAGLKVTSKSGKLIKTIKDEKFG-PVYAVGFNKLNNLMYVV 965
            N L Q+Q+  P G    E +    V LE      +WP   L   +GQVSGL+  PK  L IFHR D   DE SF+    YQ+   GPI+EST   +  D + +KV+   G NLF+LPHG+  D+  +   TD+A HQV ++      P L+LG+ F PG+D  HFC+PT  AV    G  FV+DGYCNSRI++F  +G FI ++G+    +     +  IPH L ++     +C ADREN R+QC+ A      ++GK +K IK  +FG  V+AV +     ++Y V
Sbjct:  475 NTLPQVQQGRPAGADTREKQHLGDVHLEEDT---DWPGVNL--KVGQVSGLALDPKNNLVIFHRGDHVWDENSFDRNFVYQQRGIGPIQEST--ILVVDPNTSKVLKSAGKNLFFLPHGLTIDRDGNYWVTDVALHQVFKLGAEKETPLLVLGKAFQPGSDRKHFCQPTDVAVDPITGNFFVSDGYCNSRIMQFSPNGMFIMQWGDETSSTIPKPGQFRIPHSLTMVPDHGQLCVADRENGRIQCFHA------ETGKFVKQIKHREFGREVFAVSYAP-GGVLYAV 747
[Close]
BLAST of Peptidyl-glycine alpha-amidating monooxygenase vs. Ensembl Xenopus
Match: pam (peptidylglycine alpha-amidating monooxygenase [Source:NCBI gene;Acc:100170159])

HSP 1 Score: 179.489 bits (454), Expect = 6.886e-48
Identity = 114/287 (39.72%), Postives = 160/287 (55.75%), Query Frame = 3 
Query:  135 NELNQLQKS-PVGKVAVENKPF-KVTLENANLVPNWPSSKLLDYLGQVSGLSFCPKGYLYIFHRADVEMDERSFNNKNQYQKLSDGPIKESTXXXXXXXXXXAKVVGEFGSNLFYLPHGIFADKH-HMIATDLARHQVLRIPHNSNKPDLILGEIFTPGNDANHFCKPTH-AVAAEDGTIFVADGYCNSRIVKFDKHGKFIGEFGNAKDKS-----RLSIPHHLVLIESKDLICAADRENMRVQCYSAGLKVTSKSGKLIKTIKDEKFG-PVYAVGFNKLNNLMYVV 965
            N L Q+Q+  P G    E +    V LE      +WP   L   +GQVSGL+  PK  L IFHR D   DE SF+    YQ+   GPI+EST   +  D + +KV+   G NLF+LPHG+  D+  +   TD+A HQV ++      P L+LG+ F PG+D  HFC+PT  AV    G  FV+DGYCNSRI++F  +G FI ++G+    +     +  IPH L ++     +C ADREN R+QC+ A      ++GK +K IK  +FG  V+AV +     ++Y V
Sbjct:  475 NTLPQVQQGRPAGADTREKQHLGDVHLEEDT---DWPGVNL--KVGQVSGLALDPKNNLVIFHRGDHVWDENSFDRNFVYQQRGIGPIQEST--ILVVDPNTSKVLKSAGKNLFFLPHGLTIDRDGNYWVTDVALHQVFKLGAEKETPLLVLGKAFQPGSDRKHFCQPTDVAVDPITGNFFVSDGYCNSRIMQFSPNGMFIMQWGDETSSTIPKPGQFRIPHSLTMVPDHGQLCVADRENGRIQCFHA------ETGKFVKQIKHREFGREVFAVSYAP-GGVLYAV 747
[Close]
BLAST of Peptidyl-glycine alpha-amidating monooxygenase vs. Ensembl Xenopus
Match: pam (peptidylglycine alpha-amidating monooxygenase [Source:NCBI gene;Acc:100170159])

HSP 1 Score: 179.489 bits (454), Expect = 7.057e-48
Identity = 114/288 (39.58%), Postives = 161/288 (55.90%), Query Frame = 3 
Query:  135 NELNQLQKS-PVGKVAVENKPF-KVTLENANLVPNWPSSKLLDYLGQVSGLSFCPKGYLYIFHRADVEMDERSFNNKNQYQKLSDGPIKESTXXXXXXXXXXAKVVGEFGSNLFYLPHGIFADKH-HMIATDLARHQVLRIPHNSNKPDLILGEIFTPGNDANHFCKPTH-AVAAEDGTIFVADGYCNSRIVKFDKHGKFIGEFGNAKDKS-----RLSIPHHLVLIESKDLICAADRENMRVQCYSAGLKVTSKSGKLIKTIKDEKFG-PVYAVGFNKLNNLMYVVS 968
            N L Q+Q+  P G    E +    V LE      +WP   L   +GQVSGL+  PK  L IFHR D   DE SF+    YQ+   GPI+EST   +  D + +KV+   G NLF+LPHG+  D+  +   TD+A HQV ++      P L+LG+ F PG+D  HFC+PT  AV    G  FV+DGYCNSRI++F  +G FI ++G+    +     +  IPH L ++     +C ADREN R+QC+ A      ++GK +K IK  +FG  V+AV +     ++Y V+
Sbjct:  446 NTLPQVQQGRPAGADTREKQHLGDVHLEEDT---DWPGVNL--KVGQVSGLALDPKNNLVIFHRGDHVWDENSFDRNFVYQQRGIGPIQEST--ILVVDPNTSKVLKSAGKNLFFLPHGLTIDRDGNYWVTDVALHQVFKLGAEKETPLLVLGKAFQPGSDRKHFCQPTDVAVDPITGNFFVSDGYCNSRIMQFSPNGMFIMQWGDETSSTIPKPGQFRIPHSLTMVPDHGQLCVADRENGRIQCFHA------ETGKFVKQIKHREFGREVFAVSYAP-GGVLYAVN 719
[Close]
BLAST of Peptidyl-glycine alpha-amidating monooxygenase vs. Ensembl Mouse
Match: Pam (peptidylglycine alpha-amidating monooxygenase [Source:MGI Symbol;Acc:MGI:97475])

HSP 1 Score: 172.555 bits (436), Expect = 9.847e-46
Identity = 121/347 (34.87%), Postives = 176/347 (50.72%), Query Frame = 3 
Query:  234 WPSSKLLDYLGQVSGLSFCPKGYLYIFHRADVEMDERSFNNKNQYQKLSDGPIKESTXXXXXXXXXXAKVVGEFGSNLFYLPHGIFADKH-HMIATDLARHQVLRI-PHNSNKPDLILGEIFTPGNDANHFCKPTH-AVAAEDGTIFVADGYCNSRIVKFDKHGKFIGEFGNAKDKS-----RLSIPHHLVLIESKDLICAADRENMRVQCYSAGLKVTSKSGKLIKTIKDEKFGP-VYAVGFNKLNNLMYVVS--DMVDDTDRSRVFIYNWELDMVIGVMDYSGTNGFGMAHTIDVCPRGHCVAIGSLTKECPSDLINCLERGNDEEDFQLRNVWLYQLLDAKLDL 1241
            WP   LL   GQVSG++   K  L IFHR D   D  SF++K  YQ+   GPI+E TI+ I+ +   A+++   G NLFYLPHG+  D   +   TD+A HQV ++ P +   P L+LG    PG+D NHFC+PT  AV    G +FV+DGYCNSRIV+F   GKFI ++G     S     + S+PH L L+   + +C ADREN R+QC+    K      + ++ IK   FG  V+A+ +  +   ++ V+      D +  + F+ N+    +I V      + F M H I V      V IG                     D     VW + L +++L++
Sbjct:  401 WPGVYLLP--GQVSGVALDSKNNLVIFHRGDHVWDGNSFDSKFVYQQRGLGPIEEDTILVIDPNK--AEILQSSGKNLFYLPHGLSIDTDGNYWVTDVALHQVFKLEPRSKEGPLLVLGRSMQPGSDQNHFCQPTDVAVEPSTGAVFVSDGYCNSRIVQFSPSGKFITQWGEESSGSSPKPGQFSVPHSLALVPHLNQLCVADRENGRIQCFKTDTK------EFVREIKHASFGRNVFAISY--IPGFLFAVNGKPYFGDQEPVQGFVMNFSSGEIIDVFKPVRKH-FDMPHDI-VASEDGTVYIG---------------------DAHTNTVWKFTLTESRLEV 712
[Close]
BLAST of Peptidyl-glycine alpha-amidating monooxygenase vs. Ensembl Mouse
Match: Pam (peptidylglycine alpha-amidating monooxygenase [Source:MGI Symbol;Acc:MGI:97475])

HSP 1 Score: 172.555 bits (436), Expect = 1.135e-45
Identity = 121/347 (34.87%), Postives = 176/347 (50.72%), Query Frame = 3 
Query:  234 WPSSKLLDYLGQVSGLSFCPKGYLYIFHRADVEMDERSFNNKNQYQKLSDGPIKESTXXXXXXXXXXAKVVGEFGSNLFYLPHGIFADKH-HMIATDLARHQVLRI-PHNSNKPDLILGEIFTPGNDANHFCKPTH-AVAAEDGTIFVADGYCNSRIVKFDKHGKFIGEFGNAKDKS-----RLSIPHHLVLIESKDLICAADRENMRVQCYSAGLKVTSKSGKLIKTIKDEKFGP-VYAVGFNKLNNLMYVVS--DMVDDTDRSRVFIYNWELDMVIGVMDYSGTNGFGMAHTIDVCPRGHCVAIGSLTKECPSDLINCLERGNDEEDFQLRNVWLYQLLDAKLDL 1241
            WP   LL   GQVSG++   K  L IFHR D   D  SF++K  YQ+   GPI+E TI+ I+ +   A+++   G NLFYLPHG+  D   +   TD+A HQV ++ P +   P L+LG    PG+D NHFC+PT  AV    G +FV+DGYCNSRIV+F   GKFI ++G     S     + S+PH L L+   + +C ADREN R+QC+    K      + ++ IK   FG  V+A+ +  +   ++ V+      D +  + F+ N+    +I V      + F M H I V      V IG                     D     VW + L +++L++
Sbjct:  507 WPGVYLLP--GQVSGVALDSKNNLVIFHRGDHVWDGNSFDSKFVYQQRGLGPIEEDTILVIDPNK--AEILQSSGKNLFYLPHGLSIDTDGNYWVTDVALHQVFKLEPRSKEGPLLVLGRSMQPGSDQNHFCQPTDVAVEPSTGAVFVSDGYCNSRIVQFSPSGKFITQWGEESSGSSPKPGQFSVPHSLALVPHLNQLCVADRENGRIQCFKTDTK------EFVREIKHASFGRNVFAISY--IPGFLFAVNGKPYFGDQEPVQGFVMNFSSGEIIDVFKPVRKH-FDMPHDI-VASEDGTVYIG---------------------DAHTNTVWKFTLTESRLEV 818
[Close]
BLAST of Peptidyl-glycine alpha-amidating monooxygenase vs. Ensembl Mouse
Match: Pam (peptidylglycine alpha-amidating monooxygenase [Source:MGI Symbol;Acc:MGI:97475])

HSP 1 Score: 172.555 bits (436), Expect = 1.226e-45
Identity = 121/347 (34.87%), Postives = 176/347 (50.72%), Query Frame = 3 
Query:  234 WPSSKLLDYLGQVSGLSFCPKGYLYIFHRADVEMDERSFNNKNQYQKLSDGPIKESTXXXXXXXXXXAKVVGEFGSNLFYLPHGIFADKH-HMIATDLARHQVLRI-PHNSNKPDLILGEIFTPGNDANHFCKPTH-AVAAEDGTIFVADGYCNSRIVKFDKHGKFIGEFGNAKDKS-----RLSIPHHLVLIESKDLICAADRENMRVQCYSAGLKVTSKSGKLIKTIKDEKFGP-VYAVGFNKLNNLMYVVS--DMVDDTDRSRVFIYNWELDMVIGVMDYSGTNGFGMAHTIDVCPRGHCVAIGSLTKECPSDLINCLERGNDEEDFQLRNVWLYQLLDAKLDL 1241
            WP   LL   GQVSG++   K  L IFHR D   D  SF++K  YQ+   GPI+E TI+ I+ +   A+++   G NLFYLPHG+  D   +   TD+A HQV ++ P +   P L+LG    PG+D NHFC+PT  AV    G +FV+DGYCNSRIV+F   GKFI ++G     S     + S+PH L L+   + +C ADREN R+QC+    K      + ++ IK   FG  V+A+ +  +   ++ V+      D +  + F+ N+    +I V      + F M H I V      V IG                     D     VW + L +++L++
Sbjct:  507 WPGVYLLP--GQVSGVALDSKNNLVIFHRGDHVWDGNSFDSKFVYQQRGLGPIEEDTILVIDPNK--AEILQSSGKNLFYLPHGLSIDTDGNYWVTDVALHQVFKLEPRSKEGPLLVLGRSMQPGSDQNHFCQPTDVAVEPSTGAVFVSDGYCNSRIVQFSPSGKFITQWGEESSGSSPKPGQFSVPHSLALVPHLNQLCVADRENGRIQCFKTDTK------EFVREIKHASFGRNVFAISY--IPGFLFAVNGKPYFGDQEPVQGFVMNFSSGEIIDVFKPVRKH-FDMPHDI-VASEDGTVYIG---------------------DAHTNTVWKFTLTESRLEV 818
[Close]
BLAST of Peptidyl-glycine alpha-amidating monooxygenase vs. Ensembl Mouse
Match: Pam (peptidylglycine alpha-amidating monooxygenase [Source:MGI Symbol;Acc:MGI:97475])

HSP 1 Score: 81.6481 bits (200), Expect = 6.494e-18
Identity = 42/106 (39.62%), Postives = 60/106 (56.60%), Query Frame = 3 
Query:  636 AVAAEDGTIFVADGYCNSRIVKFDKHGKFIGEFGNAKDKS-----RLSIPHHLVLIESKDLICAADRENMRVQCYSAGLKVTSKSGKLIKTIKDEKFG-PVYAVGF 935
            AV    G +FV+DGYCNSRIV+F   GKFI ++G     S     + S+PH L L+   + +C ADREN R+QC+    K      + ++ IK   FG  V+A+ +
Sbjct:    4 AVEPSTGAVFVSDGYCNSRIVQFSPSGKFITQWGEESSGSSPKPGQFSVPHSLALVPHLNQLCVADRENGRIQCFKTDTK------EFVREIKHASFGRNVFAISY 103
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BLAST of Peptidyl-glycine alpha-amidating monooxygenase vs. UniProt/SwissProt
Match: sp|Q9W1L5|PAL2_DROME (Peptidyl-alpha-hydroxyglycine alpha-amidating lyase 2 OS=Drosophila melanogaster OX=7227 GN=Pal2 PE=1 SV=2)

HSP 1 Score: 185.267 bits (469), Expect = 4.006e-52
Identity = 98/238 (41.18%), Postives = 135/238 (56.72%), Query Frame = 3 
Query:  222 LVPNWPSSKLLDYLGQVSGLSFCPKGYLYIFHRADVEMDERSFNNKNQYQKLSDGPIKESTXXXXXXXXXXAKVVGEFGSNLFYLPHGIFADKH-HMIATDLARHQVLRIPHNSNKPDLILGEIFTPGNDANHFCKPTHAVAAEDGTIFVADGYCNSRIVKFDKHGKFIGEFGNAKDKSRLSIPHHLVLIESKDLICAADRENMRVQCYSAGLKVTSKSGKLIKTIKDEKFGPVYAVG 932
            LV NWP+ +     GQV+ ++  P+G   +FHRA+   D  +FN  N Y  +  GPIKE+TI  ++      K    +GSN+FY+PHG+  D H +   TD+A HQ  +    SNKP L +G+ F PG+   H CKPT    A  G  F+ADGYCNSRI+KF+  GK +       +   L +PH + L+E  DL+C ADRENMRV C  AGL  +   G+   TI++   G V+ V 
Sbjct:  101 LVENWPTEQ--HSFGQVTAVAVDPQGSPVVFHRAERYWDVNTFNESNIYYLIEYGPIKENTIYVLDAKTGAIK--SGWGSNMFYMPHGLTIDLHGNYWITDVAMHQAFKFKPFSNKPLLTIGKRFRPGSSVKHLCKPTSIAVATTGEFFIADGYCNSRILKFNAAGKLLRTIPQPPEFLSLQVPHAITLLEHLDLLCIADRENMRVVCPKAGLISSHGEGEPAATIQEPDLGRVFGVA 334
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BLAST of Peptidyl-glycine alpha-amidating monooxygenase vs. UniProt/SwissProt
Match: sp|P12890|AMDB_XENLA (Peptidyl-glycine alpha-amidating monooxygenase B OS=Xenopus laevis OX=8355 GN=pam-b PE=2 SV=1)

HSP 1 Score: 182.956 bits (463), Expect = 1.637e-48
Identity = 107/253 (42.29%), Postives = 147/253 (58.10%), Query Frame = 3 
Query:  231 NWPSSKLLDYLGQVSGLSFCPKGYLYIFHRADVEMDERSFNNKNQYQKLSDGPIKESTXXXXXXXXXXAKVVGEFGSNLFYLPHGIFADKH-HMIATDLARHQVLRIPHNSNKPDLILGEIFTPGNDANHFCKPTH-AVAAEDGTIFVADGYCNSRIVKFDKHGKFIGEFG-----NAKDKSRLSIPHHLVLIESKDLICAADRENMRVQCYSAGLKVTSKSGKLIKTIKDEKFG-PVYAVGFNKLNNLMYVV 965
            +WP   L   +GQVSGL+  PK  L IFHR D   DE SF+    YQ+   GPI+EST   +  D + +KV+   G NLF+LPHG+  D+  +   TD+A HQV ++      P L+LG  F PG+D  HFC+PT  AV    G  FVADGYCNSRI++F  +G FI ++G     N     +  IPH L +I  +  +C ADREN R+QC+ A      K+G+ +K IK ++FG  V+AV +     ++Y V
Sbjct:  403 DWPGVNL--KVGQVSGLALDPKNNLVIFHRGDHVWDENSFDRNFVYQQRGIGPIQEST--ILVVDPNTSKVLKSTGQNLFFLPHGLTIDRDGNYWVTDVALHQVFKVGAEKETPLLVLGRAFQPGSDRKHFCQPTDVAVDPITGNFFVADGYCNSRIMQFSPNGMFIMQWGEETSSNLPRPGQFRIPHSLTMISDQGQLCVADRENGRIQCFHA------KTGEFVKQIKHQEFGREVFAVSYAP-GGVLYAV 644
[Close]
BLAST of Peptidyl-glycine alpha-amidating monooxygenase vs. UniProt/SwissProt
Match: sp|P08478|AMDA_XENLA (Peptidyl-glycine alpha-amidating monooxygenase A OS=Xenopus laevis OX=8355 GN=pam-a PE=1 SV=3)

HSP 1 Score: 180.644 bits (457), Expect = 1.472e-47
Identity = 105/253 (41.50%), Postives = 146/253 (57.71%), Query Frame = 3 
Query:  231 NWPSSKLLDYLGQVSGLSFCPKGYLYIFHRADVEMDERSFNNKNQYQKLSDGPIKESTXXXXXXXXXXAKVVGEFGSNLFYLPHGIFADKH-HMIATDLARHQVLRIPHNSNKPDLILGEIFTPGNDANHFCKPTH-AVAAEDGTIFVADGYCNSRIVKFDKHGKFIGEFG-----NAKDKSRLSIPHHLVLIESKDLICAADRENMRVQCYSAGLKVTSKSGKLIKTIKDEKFG-PVYAVGFNKLNNLMYVV 965
            +WP   L   +GQVSGL+  PK  L IFHR D   DE SF+    YQ+   GPI+EST   +  D  ++KV+   G NLF+LPHG+  D+  +   TD+A HQV ++      P L+LG  F PG+D  HFC+PT  AV    G  FVADGYCNSRI++F  +G FI ++G     N     +  IPH L ++  +  +C ADREN R+QC+ A      ++G  +K IK ++FG  V+AV +     ++Y V
Sbjct:  399 DWPGVNL--KVGQVSGLALDPKNNLAIFHRGDHVWDENSFDRNFVYQQRGIGPIQEST--ILVVDPSSSKVLKSTGKNLFFLPHGLTIDRDGNYWVTDVALHQVFKLGAGKETPLLVLGRAFQPGSDRKHFCQPTDVAVDPITGNFFVADGYCNSRIMQFSPNGMFIMQWGEETSSNVPRPGQFRIPHSLTMVPDQGQLCVADRENGRIQCFHA------ETGNFVKQIKHQEFGREVFAVSYAP-GGVLYAV 640
[Close]
BLAST of Peptidyl-glycine alpha-amidating monooxygenase vs. UniProt/SwissProt
Match: sp|P91268|PGAL_CAEEL (Probable peptidyl-alpha-hydroxyglycine alpha-amidating lyase pgal-1 OS=Caenorhabditis elegans OX=6239 GN=pgal-1 PE=1 SV=2)

HSP 1 Score: 170.244 bits (430), Expect = 4.839e-47
Identity = 99/230 (43.04%), Postives = 134/230 (58.26%), Query Frame = 3 
Query:  261 LGQVSGLSFCPKGYLYIFHRADVEMDERSFNNKNQYQKLSDGPIKESTXXXXXXXXXXAKVVGEFGSNLFYLPHGIFADKH-HMIATDLARHQVLRIPHNSNKPDLILGEIFTPGNDANHFCKPTHAVAAEDGTIFVADGYCNSRIVKFDKHGKFIGEFGNAKDK---SRLSIPHHLVLIESKDLICAADRENMRVQCYSAGLK---VTSKSGKLIKTIKDEKFGPVYAV 929
            +GQVSGL+    G++  FHR+    DE+SFN+   + K   G I   TI  I+ +    KV+ EFG+ LFY+PHG+  D +     TD+  HQV +I   + K  + LGE   PG D  HFCKPT    A++G IFVADGYCNSRI+KFD  G  + +   A ++   S   +PH L LIE  +++C ADREN RVQC+SAGL     T  +G  I +  D   G V+A+
Sbjct:   59 IGQVSGLAVNKNGHIVAFHRSGRVWDEKSFNDHETFNK-DLGVINNKTIAIISREK---KVIDEFGAGLFYMPHGLTIDNNGDYWVTDVGSHQVHKIDAKTQKIVMSLGEKMVPGEDQAHFCKPTDVAVAKNGHIFVADGYCNSRILKFDAKGNLMAQINAATEENQPSEFVVPHSLSLIEDMNIVCVADRENQRVQCFSAGLSEGDRTLPTGIPITSATD--IGRVFAI 282
[Close]
BLAST of Peptidyl-glycine alpha-amidating monooxygenase vs. UniProt/SwissProt
Match: sp|P19021|AMD_HUMAN (Peptidyl-glycine alpha-amidating monooxygenase OS=Homo sapiens OX=9606 GN=PAM PE=1 SV=2)

HSP 1 Score: 177.948 bits (450), Expect = 1.161e-46
Identity = 117/296 (39.53%), Postives = 164/296 (55.41%), Query Frame = 3 
Query:  231 NWPSSKLLDYLGQVSGLSFCPKGYLYIFHRADVEMDERSFNNKNQYQKLSDGPIKESTXXXXXXXXXXAKVVGEFGSNLFYLPHGIFADKH-HMIATDLARHQVLRI-PHNSNKPDLILGEIFTPGNDANHFCKPTH-AVAAEDGTIFVADGYCNSRIVKFDKHGKFIGEFGNAKDKS-----RLSIPHHLVLIESKDLICAADRENMRVQCYSAGLKVTSKSGKLIKTIKDEKFGP-VYAVGFNKLNNLMYVVSDMVDDTDRSRV--FIYNWELDMVIGVMDYSGTNGFGMAHTI 1085
            +WP   LL   GQVSG++  PK  L IFHR D   D  SF++K  YQ++  GPI+E T   +  D +NA V+   G NLFYLPHG+  DK  +   TD+A HQV ++ P+N   P LILG    PG+D NHFC+PT  AV    G I+V+DGYCNSRIV+F   GKFI ++G     S     + ++PH L L+     +C ADREN R+QC+    K      + ++ IK   FG  V+A+ +  +  L++ V+      D+  V  F+ N+    +I +      + F M H I
Sbjct:  503 DWPGVYLLP--GQVSGVALDPKNNLVIFHRGDHVWDGNSFDSKFVYQQIGLGPIEEDT--ILVIDPNNAAVLQSSGKNLFYLPHGLSIDKDGNYWVTDVALHQVFKLDPNNKEGPVLILGRSMQPGSDQNHFCQPTDVAVDPGTGAIYVSDGYCNSRIVQFSPSGKFITQWGEESSGSSPLPGQFTVPHSLALVPLLGQLCVADRENGRIQCFKTDTK------EFVREIKHSSFGRNVFAISY--IPGLLFAVNGKPHFGDQEPVQGFVMNFSNGEIIDIFKPVRKH-FDMPHDI 785
[Close]
BLAST of Peptidyl-glycine alpha-amidating monooxygenase vs. TrEMBL
Match: A0A267FBA0 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig022186g1 PE=4 SV=1)

HSP 1 Score: 243.047 bits (619), Expect = 1.022e-71
Identity = 142/354 (40.11%), Postives = 202/354 (57.06%), Query Frame = 3 
Query:  228 PNWPSSKLLDYLGQVSGLSFCPKGYLYIFHRADVEMDERSFNNKNQYQKLSDGPIKESTXXXXXXXXXXAKVVGEFGSNLFYLPHGIFADKH-HMIATDLARHQVLRIPHNSNKPDLILGEIFTPGNDANHFCKPTHAVAAEDGTIFVADGYCNSRIVKFDKHGKFIGEFG---NAKDKSRLS-----IPHHLVLIESKDLICAADRENMRVQCYSAGLKVTSKSGKLIKTIKD-EKFGPVYAVGFNKLNNLMYVVSDMVDDTDRSRVFIYNWELDMVIGVMDYSGTN------GFGMAHTIDVCPRGHCVAIGSLTKECPSDLINCLERGNDEEDF-QLRNVWLYQLLDAKLD 1238
            PNW   +L   LGQVSG+S C KG  ++F RAD       F+   +Y K   GPI+ STII++++     ++V   G N+FYLPHGI  DK  H+  TD+ARHQV+R+  ++ KPDL++GE F PGNDA+HFCKPT    A DG  FVADGYCNSR++KFD  GK+IGEFG   +A   + L+     +PH L L ES DL+C ADRE+ RVQC+ AGL+  +  G+ ++++   +  G V+ V F+   NL+ +     +D+  S V ++  E   ++    +   N      GFG  H++   PRG    + SL+  C          G DEE F ++     YQ+    +D
Sbjct:   56 PNW---RLRQLLGQVSGVSICAKGRSFLFQRADRPWQADDFDEHERYTKAERGPIEVSTIIELDSV---GRLVSSLGENIFYLPHGITVDKEGHLWTTDVARHQVIRLNKDTRKPDLVIGEKFVPGNDASHFCKPTKVAVASDGHFFVADGYCNSRVMKFDPSGKYIGEFGKRPSATPSANLADNEFLVPHGLALFESLDLLCVADREHRRVQCFHAGLRQPADFGQFVRSLGSADHLGRVFDVAFDPSGNLLVLHH---EDSGVSLVSVFRPETGGLVTRFTFVPDNSQDSMVGFGDGHSVAASPRGDFFVVSSLSAVC---------DGYDEECFGEMPTQAPYQVFKFNVD 391
[Close]
BLAST of Peptidyl-glycine alpha-amidating monooxygenase vs. TrEMBL
Match: A0A1I8HRY2 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig022186g3 PE=4 SV=1)

HSP 1 Score: 241.891 bits (616), Expect = 3.194e-71
Identity = 143/355 (40.28%), Postives = 200/355 (56.34%), Query Frame = 3 
Query:  228 PNWPSSKLLDYLGQVSGLSFCPKGYLYIFHRADVEMDERSFNNKNQYQKLSDGPIKESTXXXXXXXXXXAKVVGEFGSNLFYLPHGIFADKH-HMIATDLARHQVLRIPHNSNKPDLILGEIFTPGNDANHFCKPTHAVAAEDGTIFVADGYCNSRIVKFDKHGKFIGEFG---------NAKDKSRLSIPHHLVLIESKDLICAADRENMRVQCYSAGLKVTSKSGKLIKTIKD-EKFGPVYAVGFNKLNNLMYVVSDMVDDTDRSRVFIYNWELDMVIGVMDYSGTN------GFGMAHTIDVCPRGHCVAIGSLTKECPSDLINCLERGNDEEDF-QLRNVWLYQLLDAKLD 1238
            PNW   +L   LGQVSG+S C KG  ++F RAD       F+   +Y K   GPI+ STII++++     ++V   G N+FYLPHGI  DK  H+  TD+ARHQV+R+  ++ KPDL++GE F PGNDA+HFCKPT    A DG  FVADGYCNSR++KFD  GK+IGEFG         N  D   L +PH L L ES DL+C ADRE+ RVQC+ AGL+  +  G+ ++++   +  G V+ V F+   NL+ +     +D+  S V ++  E   ++    +   N      GFG  H++   PRG    + SL+  C          G DEE F ++     YQ+    +D
Sbjct:   56 PNW---RLRQLLGQVSGVSICAKGRSFLFQRADRPWQADDFDEHERYTKAERGPIEVSTIIELDSV---GRLVSSIGENIFYLPHGITVDKDGHLWTTDVARHQVIRLNKDTRKPDLVIGEKFVPGNDASHFCKPTKVAVASDGHFFVADGYCNSRVMKFDPSGKYIGEFGKRPSATPGANLADNEFL-VPHGLALFESLDLLCVADREHRRVQCFHAGLRQPADFGQFVRSLGSADDLGRVFDVAFDPSGNLLVLHH---EDSGVSLVSVFRPETGGLVTRFTFVPDNSQDSMVGFGDGHSVAASPRGDFFVVSSLSAVC---------DGYDEECFGEMPTQAPYQVFKFNVD 391
[Close]
BLAST of Peptidyl-glycine alpha-amidating monooxygenase vs. TrEMBL
Match: A0A267GR20 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig022186g2 PE=4 SV=1)

HSP 1 Score: 227.254 bits (578), Expect = 1.347e-66
Identity = 120/256 (46.88%), Postives = 162/256 (63.28%), Query Frame = 3 
Query:  228 PNWPSSKLLDYLGQVSGLSFCPKGYLYIFHRADVEMDERSFNNKNQYQKLSDGPIKESTXXXXXXXXXXAKVVGEFGSNLFYLPHGIFADKH-HMIATDLARHQVLRIPHNSNKPDLILGEIFTPGNDANHFCKPTHAVAAEDGTIFVADGYCNSRIVKFDKHGKFIGEFG---------NAKDKSRLSIPHHLVLIESKDLICAADRENMRVQCYSAGLKVTSKSGKLIKTIKD-EKFGPVYAVGFNKLNNLMYV 962
            PNW   +L   LGQVSG+S C KG  ++F RAD       F+   +Y K   GPI+ STII++++     ++V   G N+FYLPHGI  DK  H+  TD+ARHQV+R+  ++ KPDL++GE F PGNDA+HFCKPT    A DG  FVADGYCNSR++KFD  GK+IGEFG         N  D   L +PH L L ES DL+C ADRE+ RVQC+ AGL+  +  G+ ++++   +  G V+ V F+   NL+ +
Sbjct:   56 PNW---RLRQLLGQVSGVSICAKGRSFLFQRADRPWQADDFDEHERYTKAERGPIEVSTIIELDSV---GRLVSSIGENIFYLPHGITVDKDGHLWTTDVARHQVIRLNKDTRKPDLVIGEKFVPGNDASHFCKPTKVAVASDGHFFVADGYCNSRVMKFDPSGKYIGEFGKRPSATPGANLADNEFL-VPHGLALFESLDLLCVADREHRRVQCFHAGLRQPADFGQFVRSLGSADDLGRVFDVAFDPSGNLLVL 304
[Close]
BLAST of Peptidyl-glycine alpha-amidating monooxygenase vs. TrEMBL
Match: A0A1I8IUF6 (Uncharacterized protein OS=Macrostomum lignano OX=282301 PE=4 SV=1)

HSP 1 Score: 219.935 bits (559), Expect = 6.276e-63
Identity = 139/354 (39.27%), Postives = 189/354 (53.39%), Query Frame = 3 
Query:  228 PNWPSSKLLDYLGQVSGLSFCPKGYLYIFHRADVEMDERSFNNKNQYQKLSDGPIKESTXXXXXXXXXXAKVVGEFGSNLFYLPHGIFADKH-HMIATDLARHQVLRIPHNSNKPDLILGEIFTPGNDANHFCKPTHAVAAEDGTIFVADGYCNSRIVKFDKHGKFIGEFG---------NAKDKSRLSIPHHLVLIESKDLICAADRENMRVQCYSAGLKVTSKSGKLIKTIKDEKFGPVYAVGFNKLNNLMYVVSDMVDDTDRSRVFIYNWELDMVIGVMDYSGTN------GFGMAHTIDVCPRGHCVAIGSLTKECPSDLINCLERGNDEEDF-QLRNVWLYQLLDAKLD 1238
            PNW   +L   LGQVSG+S C KG  ++F RAD       F+   +Y K   GPI+ STII++++     ++V   G N+FYLPHGI  DK  H+  TD+ARHQV+R+  ++ KPDL++GE F PGNDA+HFCKPT    A DG  FVADGYCNSR++KFD  GK+IGEFG         N  D   L +PH L L ES DL+C ADRE+ RV            SG+L   +       V+ V F+   NL+ +     +D+  S V ++  E   ++    +   N      GFG  H++   PRG    + SL+  C          G DEE F ++     YQ+    +D
Sbjct:   56 PNW---RLRQLLGQVSGVSICAKGRSFLFQRADRPWQADDFDEHERYTKAERGPIEVSTIIELDSV---GRLVSSIGENIFYLPHGITVDKDGHLWTTDVARHQVIRLNKDTRKPDLVIGEKFVPGNDASHFCKPTKVAVASDGHFFVADGYCNSRVMKFDPSGKYIGEFGKRPSATPGANLADNEFL-VPHGLALFESLDLLCVADREHRRVHL----------SGRLAARMTSAG---VFDVAFDPSGNLLVLHH---EDSGVSLVSVFRPETGGLVTRFTFVPDNSQDSMVGFGDGHSVAASPRGDFFVVSSLSAVC---------DGYDEECFGEMPTQAPYQVFKFNVD 377
[Close]
BLAST of Peptidyl-glycine alpha-amidating monooxygenase vs. TrEMBL
Match: A0A1W4WYG3 (peptidyl-alpha-hydroxyglycine alpha-amidating lyase 2-like OS=Agrilus planipennis OX=224129 GN=LOC108737040 PE=4 SV=1)

HSP 1 Score: 208.379 bits (529), Expect = 6.338e-58
Identity = 111/237 (46.84%), Postives = 146/237 (61.60%), Query Frame = 3 
Query:  225 VPNWPSSKLLDYLGQVSGLSFCPKGYLYIFHRADVEMDERSFNNKNQYQKLSDGPIKESTXXXXXXXXXXAKVVGEFGSNLFYLPHGIFADKH-HMIATDLARHQVLRIPHNSNKPDLILGEIFTPGNDANHFCKPTHAVAAEDGTIFVADGYCNSRIVKFDKHGKFIGEFGNAKDKSRLSIPHHLVLIESKDLICAADRENMRVQCYSAGLKVTSKSGKLIKTIKDEKFGPVYAVG 932
            V NWP S+L   LGQVSG++   K    IFHRAD    E +FN+ N YQ+++ GPIKE+TI+ ++      KV+ ++G+N+FY+PHGI  D+H +   TD+A HQV +     ++P L  G+ F PG+D  H CKPTHA  A  G +F+ADGYCNSRI+KF+  G  +    N  +   L +PH L LIES DLIC ADRENMRV C  AGL     S K   TI+    G V+ V 
Sbjct:   73 VKNWPDSQL--KLGQVSGVAVNSKNQPVIFHRADRIWGEFTFNDSNHYQQINLGPIKENTILTLHPTT--GKVIAQWGANMFYMPHGISFDRHDNTWVTDVALHQVFKFRPGESEPVLTFGQRFEPGSDLRHLCKPTHAAIASTGEVFIADGYCNSRILKFNAAGGLLKVIPNPPEFLSLVVPHALALIESLDLICVADRENMRVVCPRAGLYNIRDSDKQALTIQQPDMGRVFGVA 305

HSP 2 Score: 67.3958 bits (163), Expect = 3.629e-8
Identity = 43/123 (34.96%), Postives = 58/123 (47.15%), Query Frame = 3 
Query:  759 LSIPHHLVLIESKDLICAADRENMRVQCYSAGLKVTSKSGKLIKTIKDEKFGPVYAVGFNKLNNLMYVVSDMVDDTDRSRVFIYNWELDMVIGVMDYSGTNGFGMAHTIDVCPRGHCVAIGSL 1127
            L +PH L LIES DLIC ADRENMRV C  AGL     S K   TI+    G V+ V       ++Y V+         R    + + + VI    ++   GFG  H + V P G  + +  +
Sbjct:  317 LVVPHALALIESLDLICVADRENMRVVCPRAGLYNIRDSDKQALTIQQPDMGRVFGVA--SRGEIVYAVNGPTSPFLPVRGLTIDPKSEAVID--HWAPEEGFGNPHAVAVAPNGTALYVAEI 435
[Close]
BLAST of Peptidyl-glycine alpha-amidating monooxygenase vs. Ensembl Cavefish
Match: pam (peptidylglycine alpha-amidating monooxygenase [Source:NCBI gene;Acc:103031431])

HSP 1 Score: 191.43 bits (485), Expect = 3.728e-52
Identity = 130/331 (39.27%), Postives = 182/331 (54.98%), Query Frame = 3 
Query:  231 NWPSSKLLDYLGQVSGLSFCPKGYLYIFHRADVEMDERSFNNKNQYQKLSDGPIKESTXXXXXXXXXXAKVVGEFGSNLFYLPHGIFADK-HHMIATDLARHQVLRIPHN-SNKPDLILGEIFTPGNDANHFCKPTH-AVAAEDGTIFVADGYCNSRIVKFDKHGKFIGEFGNAK-DKSR---LSIPHHLVLIESKDLICAADRENMRVQCYSAGLKVTSKSGKLIKTIKDEKF-GPVYAVGFNKLN-NLMYVVS--DMVDDTDRSRVFIYNWELDMVIGVMDYSGTNGFGMAHTIDVCPRGHCVAIG-----SLTKECPSDLINCLERGN 1175
            +WP  +L   LGQVSGL+      L IFHR D   +  SF+NK  YQ+ S GPI++STI+ ++       V+   G N+FYLPHGI  DK ++   TD+A HQV ++  + + KP L+LGE F PG+D +HFCKPT  AV  E G IFV+DGYCN+RI+KF   GK++ ++G    D+ R     IPH L  +  K  +  ADREN RVQC+ A       +G+ +K IK ++F G VYAV +  +   L+YVV+       +   R F+ N+    ++       T  F M H I V   G  V +G     S+ K  PS+      + N
Sbjct:  502 DWPEVEL--QLGQVSGLAVDSDDNLVIFHRGDHRWEMNSFDNKAVYQQRSLGPIQQSTILVVDPSK--GNVLKASGKNMFYLPHGITTDKDNNYWVTDVALHQVFKLSKDGTEKPLLVLGEAFKPGSDKSHFCKPTDVAVDPETGNIFVSDGYCNTRILKFSPEGKYLSDWGAGSLDRRRRVPFQIPHSLAFVPDKRELLVADRENGRVQCFMA------DTGEFVKEIKRDEFGGEVYAVSYAPVQGGLIYVVNGESPYGQSAPLRGFVLNYSTKEILDTF-APDTQKFKMPHDIVVTKDG-SVYVGDATSDSVIKFVPSEKTETFVQAN 820
[Close]
BLAST of Peptidyl-glycine alpha-amidating monooxygenase vs. Ensembl Cavefish
Match: pam (peptidylglycine alpha-amidating monooxygenase [Source:NCBI gene;Acc:103031431])

HSP 1 Score: 191.045 bits (484), Expect = 3.880e-52
Identity = 126/313 (40.26%), Postives = 176/313 (56.23%), Query Frame = 3 
Query:  231 NWPSSKLLDYLGQVSGLSFCPKGYLYIFHRADVEMDERSFNNKNQYQKLSDGPIKESTXXXXXXXXXXAKVVGEFGSNLFYLPHGIFADK-HHMIATDLARHQVLRIPHN-SNKPDLILGEIFTPGNDANHFCKPTH-AVAAEDGTIFVADGYCNSRIVKFDKHGKFIGEFGNAK-DKSR---LSIPHHLVLIESKDLICAADRENMRVQCYSAGLKVTSKSGKLIKTIKDEKF-GPVYAVGFNKLN-NLMYVVS--DMVDDTDRSRVFIYNWELDMVIGVMDYSGTNGFGMAHTIDVCPRGHCVAIGSLTKE 1136
            +WP  +L   LGQVSGL+      L IFHR D   +  SF+NK  YQ+ S GPI++STI+ ++       V+   G N+FYLPHGI  DK ++   TD+A HQV ++  + + KP L+LGE F PG+D +HFCKPT  AV  E G IFV+DGYCN+RI+KF   GK++ ++G    D+ R     IPH L  +  K  +  ADREN RVQC+ A       +G+ +K IK ++F G VYAV +  +   L+YVV+       +   R F+ N+    ++       T  F M H I V   G  V +G  T +
Sbjct:  399 DWPEVEL--QLGQVSGLAVDSDDNLVIFHRGDHRWEMNSFDNKAVYQQRSLGPIQQSTILVVDPSK--GNVLKASGKNMFYLPHGITTDKDNNYWVTDVALHQVFKLSKDGTEKPLLVLGEAFKPGSDKSHFCKPTDVAVDPETGNIFVSDGYCNTRILKFSPEGKYLSDWGAGSLDRRRRVPFQIPHSLAFVPDKRELLVADRENGRVQCFMA------DTGEFVKEIKRDEFGGEVYAVSYAPVQGGLIYVVNGESPYGQSAPLRGFVLNYSTKEILDTF-APDTQKFKMPHDIVVTKDG-SVYVGDATSD 699
[Close]
BLAST of Peptidyl-glycine alpha-amidating monooxygenase vs. Ensembl Cavefish
Match: pam (peptidylglycine alpha-amidating monooxygenase [Source:NCBI gene;Acc:103031431])

HSP 1 Score: 191.045 bits (484), Expect = 4.472e-52
Identity = 126/314 (40.13%), Postives = 176/314 (56.05%), Query Frame = 3 
Query:  231 NWPSSKLLDYLGQVSGLSFCPKGYLYIFHRADVEMDERSFNNKNQYQKLSDGPIKESTXXXXXXXXXXAKVVGEFGSNLFYLPHGIFADK-HHMIATDLARHQVLRIPHN-SNKPDLILGEIFTPGNDANHFCKPTH-AVAAEDGTIFVADGYCNSRIVKFDKHGKFIGEFGNAK-DKSR---LSIPHHLVLIESKDLICAADRENMRVQCYSAGLKVTSKSGKLIKTIKDEKF-GPVYAVGFNKLN-NLMYVVS--DMVDDTDRSRVFIYNWELDMVIGVMDYSGTNGFGMAHTIDVCPRGHCVAIGSLTKEC 1139
            +WP  +L   LGQVSGL+      L IFHR D   +  SF+NK  YQ+ S GPI++STI+ ++       V+   G N+FYLPHGI  DK ++   TD+A HQV ++  + + KP L+LGE F PG+D +HFCKPT  AV  E G IFV+DGYCN+RI+KF   GK++ ++G    D+ R     IPH L  +  K  +  ADREN RVQC+ A       +G+ +K IK ++F G VYAV +  +   L+YVV+       +   R F+ N+    ++       T  F M H I V   G  V +G  T + 
Sbjct:  502 DWPEVEL--QLGQVSGLAVDSDDNLVIFHRGDHRWEMNSFDNKAVYQQRSLGPIQQSTILVVDPSK--GNVLKASGKNMFYLPHGITTDKDNNYWVTDVALHQVFKLSKDGTEKPLLVLGEAFKPGSDKSHFCKPTDVAVDPETGNIFVSDGYCNTRILKFSPEGKYLSDWGAGSLDRRRRVPFQIPHSLAFVPDKRELLVADRENGRVQCFMA------DTGEFVKEIKRDEFGGEVYAVSYAPVQGGLIYVVNGESPYGQSAPLRGFVLNYSTKEILDTF-APDTQKFKMPHDIVVTKDG-SVYVGDATSDS 803
[Close]
BLAST of Peptidyl-glycine alpha-amidating monooxygenase vs. Ensembl Sea Lamprey
Match: ENSPMAT00000003037.1 (pep scaffold:Pmarinus_7.0:GL480308:28740:39707:1 gene:ENSPMAG00000002773.1 transcript:ENSPMAT00000003037.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 146.747 bits (369), Expect = 4.794e-39
Identity = 96/254 (37.80%), Postives = 133/254 (52.36%), Query Frame = 3 
Query:  261 LGQVSGLSFCPKGYLYIFHRADVEMD-ERSFNNKNQYQKLSDGPIKESTXXXXXXXXXXAKVVGEFGSNLFYLPHGIFAD-KHHMIATDLARHQVLRIPHNSNK-PDLILGEIFTPGNDANHFCKPTH-AVAAEDGTIFVADGYCNSRIVKFDKHGKFIGEFGNAKDK-SRLSIPHHLVLIE------------SKDLICAADRENMRVQCYSAGLKVTSKSGKLIKTIKDEKF-GPVYAVGFNKLN-NLMYVV 965
            LGQV+GL+      +Y+FHRAD   D  RSFNN++++ +   GPI E TI+  +       +V  FG  +FYLPHG+  D +  +  TD+A HQV R+     K P L LG+   PG+ A+HFCKPT  AV       F++DGYCN RI  F   G F+ E+G    K     IPH L L+                 +C ADREN RVQC+ A        G   +TI+   F G V+++ +   +  L+YV+
Sbjct:  137 LGQVTGLAVDTDDLIYVFHRADRIWDPRRSFNNRDEFLEDHLGPIAEDTILAFDPVS--GHLVHSFGKGMFYLPHGLSIDFEGKLWVTDVALHQVFRLATGGGKEPLLTLGQRMRPGDGASHFCKPTDVAVDPRLRLAFISDGYCNGRIAVFSLDGTFVREWGTEGSKPGEFRIPHALTLVSRVSDDAGNDGGGDSSALCVADRENGRVQCFRA------DDGTRTRTIEHAAFGGRVFSLAYTPASGGLLYVL 382
[Close]
BLAST of Peptidyl-glycine alpha-amidating monooxygenase vs. Ensembl Sea Lamprey
Match: NHLRC3 (NHL repeat containing 3 [Source:HGNC Symbol;Acc:HGNC:33751])

HSP 1 Score: 50.8322 bits (120), Expect = 3.381e-7
Identity = 45/156 (28.85%), Postives = 74/156 (47.44%), Query Frame = 3 
Query:  444 VGEFGSNLFYLPHGIF----ADKHHMIATDLAR----HQVLRIPHNSNKPDLILGEIFTPGNDANHFC-----KPTHAVAAEDGTIFVADG--YCNSRIVKF----DKHGKFI-GEFGNAKDKSRLSIPHHLVLIESKDLICAADRENMRVQCYSA 851
            +G + S+   +PHGIF    A+  ++  TD+      H + R   + N    +L  + TPG     F      +P   +    G ++VADG    N+R+ K     D+  +++ GE G+ K  ++  IPH L L +S   +  ADR N R+Q + A
Sbjct:   63 LGSWNSSALEMPHGIFFLQSANNSNIWVTDVGTGEWGHSIKRFSPDGN----LLEVLGTPGKAGASFTPLQFDQPAEVIVGPRGEMYVADGDGGLNNRVFKLQSVTDRTLEWVHGEKGSGK--AQFYIPHSLCL-DSFGRLWVADRGNKRIQVFDA 211
[Close]
BLAST of Peptidyl-glycine alpha-amidating monooxygenase vs. Ensembl Sea Lamprey
Match: ENSPMAT00000005035.1 (pep scaffold:Pmarinus_7.0:GL476697:205350:209715:-1 gene:ENSPMAG00000004581.1 transcript:ENSPMAT00000005035.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 47.3654 bits (111), Expect = 3.740e-6
Identity = 41/130 (31.54%), Postives = 64/130 (49.23%), Query Frame = 3 
Query:  468 FYLPHGI-FADKHHMIATDLARHQVLRIPHNSNKPDLILGEIFTPGNDANHF-CKPTHAVAAEDGTIFVADGYCNSRIVKFDKHGKFIGEFGN-AKDKSRLSIPHHLVLIESKDLICAADRENMRVQCYS 848
            F  P G+    + H+I  D + H+ L++   S +    +  I + G+    F C     V A+ G I VAD Y N R+  FD+ G+F+  FG     + +LS P   V  +S  L+   D++N RVQ +S
Sbjct:   17 FTWPRGLAVTPEGHLIVADSSNHR-LQVFDWSGR---FIRAIGSHGSGDGQFDCLSGVTVNAQLGLILVADRY-NHRVQIFDRTGRFLRAFGREGAGRGQLSYPWG-VACDSSGLVYVCDKDNHRVQVFS 140
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BLAST of Peptidyl-glycine alpha-amidating monooxygenase vs. Ensembl Nematostella
Match: EDO42139 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S2F4])

HSP 1 Score: 158.303 bits (399), Expect = 2.441e-41
Identity = 102/281 (36.30%), Postives = 153/281 (54.45%), Query Frame = 3 
Query:  156 KSPVGKVAVENKPFKVTLENA------NLVPNWPSSKLL--DYLGQVSGLSFCPKGYLYIFHRADVEMDERSFNNKNQYQKLSDGPIKESTXXXXXXXXXXAKVVGEFGSNLFYLPHGIFAD-KHHMIATDLARHQVLRIPHN-SNKPDLILGEIFTPGNDANHFCKPTHAVAAEDGTIFVADGYCNSRIVKFDKHGKFIGEFGNAKDKSRLSIP---------HHLVLIESKDLICAADRENMRVQCYSAGLKVTSKSGKLIKTIKDEKFGP-VYAVGFN 938
            KSPVG   V+    +  LEN       +LV NWP   LL  + LGQVS ++   +G + +FHR     D +SF+  N +Q+ +  PI+E T+   +      K++G +G + FY+PHG+  D + +   TD+A HQV +   + S++P L+LGE+  PG+D  HFC+P        G  +VADGYCNSR++KF   GK + ++G A     L  P         H L L ++   +  ADREN RVQ      ++ +K G+  + I +++FG  VYAV FN
Sbjct:  379 KSPVGIGLVQKSSPQSALENPLNKLRYHLVENWP---LLGQETLGQVSAVALDMRGNVVVFHRGSRAWDLKSFDRDNVFQERT--PIREHTVTTFDRKT--GKIIGRWGRDRFYMPHGLTIDHEDNTWITDVALHQVHKYGTDGSSEPVLVLGEMLRPGSDDKHFCQPNDVAIETTGVFYVADGYCNSRVMKFSPEGKLLEQYGKAMSARGLGSPPPLGVFDVVHSLALDQTHHHLYVADRENGRVQ------RLDTKKGRFDREITNKEFGASVYAVDFN 646
[Close]
BLAST of Peptidyl-glycine alpha-amidating monooxygenase vs. Ensembl Nematostella
Match: EDO29851 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T2G3])

HSP 1 Score: 57.3806 bits (137), Expect = 9.319e-9
Identity = 44/153 (28.76%), Postives = 70/153 (45.75%), Query Frame = 3 
Query:  555 NSNKPDLILGEIFTPGNDANHFCKPTHAVAAEDGTIFVADGYCNSRIVKFDKHGKFIGEFGNAKDKS-RLSIPHHLVLIESKDLICAADRENMRVQCYSAGLKVTSKSGKLIKTIKDEKFGPVYAVGFNKLNNLMYVVSDMVDDTDRSRVFIY 1010
            N N    +L    + G      C+P       +G+I VAD   N+RI  FD +G F+ +FG+A  ++ +   P  +     +D I  AD++N RVQ +S       K G+  K  K+ +F   + V  N   N+      +V DT   RV ++
Sbjct:  298 NYNGVGPVLLSFGSEGESGGQLCRPWGVCCDRNGSIIVAD-RSNNRIQIFDNYGNFVHKFGSAGSRNGQFDRPAGVTCDHERDRIIVADKDNHRVQVFSLDGTFLLKFGE--KGSKNGQFSYPWDVAVNSEGNI------LVSDTRNHRVQLF 441
[Close]
BLAST of Peptidyl-glycine alpha-amidating monooxygenase vs. Ensembl Medaka
Match: pam (peptidylglycine alpha-amidating monooxygenase [Source:NCBI gene;Acc:101164528])

HSP 1 Score: 188.734 bits (478), Expect = 1.880e-51
Identity = 115/314 (36.62%), Postives = 178/314 (56.69%), Query Frame = 3 
Query:  225 VPNWPSSKLLDYLGQVSGLSFCPKGYLYIFHRADVEMDERSFNNKNQYQKLSDGPIKESTXXXXXXXXXXAKVVGEFGSNLFYLPHGIFADK-HHMIATDLARHQVLRIPHNS-NKPDLILGEIFTPGNDANHFCKPTH-AVAAEDGTIFVADGYCNSRIVKFDKHGKFIGEFG----NAKDKSRLSIPHHLVLIESKDLICAADRENMRVQCYSAGLKVTSKSGKLIKTIKDEKF-GPVYAVGFNKL-NNLMYVVS-DMVDDTDRSRVFIYNWELDMVIGVMDYSGTNGFGMAHTIDVCPRGHCVAIGSLTKE 1136
            V +WP   L   LGQVSGL+      L IFHR D   D  SF+ + +YQ  S GPI++S I+ ++      +++   G N+FYLPHGI AD+ ++   TD+A HQVL++  +  ++  L LGE FTPG+D++HFC+PT  A+    G +FV+DGYCN+RI+KF   GK++ ++G    + + ++R  IPH L  +  +  +C ADREN R+QC+ A       +G+ +K IK E+F G V+A+ ++   + L+Y V+ D    +   R F+ N+    ++          F M H +   P G  V +G    E
Sbjct:  413 VTDWPEGNL--QLGQVSGLALDSDSNLVIFHRGDHHWDLDSFDGRARYQHRSLGPIQQSAILVVDPAK--GRILKASGRNMFYLPHGITADRDNNYWVTDVALHQVLKVSSDGRDRTLLALGEAFTPGSDSSHFCQPTDVAIDPHTGNVFVSDGYCNARILKFSADGKYLSQWGAGSLDRRQRARFQIPHSLAFLSDRREVCVADRENGRIQCFIA------DTGEFVKEIKKEEFGGKVFAISYSPAGDGLIYAVNGDSPYHSAPLRGFVINYTSREILDTFSPKRKQDFKMPHDLVGGPDG-SVFVGDAGSE 715
[Close]
BLAST of Peptidyl-glycine alpha-amidating monooxygenase vs. Ensembl Medaka
Match: pam (peptidylglycine alpha-amidating monooxygenase [Source:NCBI gene;Acc:101164528])

HSP 1 Score: 188.348 bits (477), Expect = 2.395e-51
Identity = 115/314 (36.62%), Postives = 177/314 (56.37%), Query Frame = 3 
Query:  225 VPNWPSSKLLDYLGQVSGLSFCPKGYLYIFHRADVEMDERSFNNKNQYQKLSDGPIKESTXXXXXXXXXXAKVVGEFGSNLFYLPHGIFADK-HHMIATDLARHQVLRIPHNSNKPDLI-LGEIFTPGNDANHFCKPTH-AVAAEDGTIFVADGYCNSRIVKFDKHGKFIGEFG----NAKDKSRLSIPHHLVLIESKDLICAADRENMRVQCYSAGLKVTSKSGKLIKTIKDEKF-GPVYAVGFNKL-NNLMYVVS-DMVDDTDRSRVFIYNWELDMVIGVMDYSGTNGFGMAHTIDVCPRGHCVAIGSLTKE 1136
            V +WP   L   LGQVSGL+      L IFHR D   D  SF+ + +YQ  S GPI++S I+ ++      +++   G N+FYLPHGI AD+ ++   TD+A HQVL++  +     L+ LGE FTPG+D++HFC+PT  A+    G +FV+DGYCN+RI+KF   GK++ ++G    + + ++R  IPH L  +  +  +C ADREN R+QC+ A       +G+ +K IK E+F G V+A+ ++   + L+Y V+ D    +   R F+ N+    ++          F M H +   P G  V +G    E
Sbjct:  384 VTDWPEGNL--QLGQVSGLALDSDSNLVIFHRGDHHWDLDSFDGRARYQHRSLGPIQQSAILVVDPAK--GRILKASGRNMFYLPHGITADRDNNYWVTDVALHQVLKVSSDGRDRTLLALGEAFTPGSDSSHFCQPTDVAIDPHTGNVFVSDGYCNARILKFSADGKYLSQWGAGSLDRRQRARFQIPHSLAFLSDRREVCVADRENGRIQCFIA------DTGEFVKEIKKEEFGGKVFAISYSPAGDGLIYAVNGDSPYHSAPLRGFVINYTSREILDTFSPKRKQDFKMPHDLVGGPDG-SVFVGDAGSE 686
[Close]
BLAST of Peptidyl-glycine alpha-amidating monooxygenase vs. Ensembl Medaka
Match: pam (peptidylglycine alpha-amidating monooxygenase [Source:NCBI gene;Acc:101164528])

HSP 1 Score: 186.808 bits (473), Expect = 1.551e-50
Identity = 112/303 (36.96%), Postives = 174/303 (57.43%), Query Frame = 3 
Query:  225 VPNWPSSKLLDYLGQVSGLSFCPKGYLYIFHRADVEMDERSFNNKNQYQKLSDGPIKESTXXXXXXXXXXAKVVGEFGSNLFYLPHGIFADK-HHMIATDLARHQVLRIPHNS-NKPDLILGEIFTPGNDANHFCKPTH-AVAAEDGTIFVADGYCNSRIVKFDKHGKFIGEFG----NAKDKSRLSIPHHLVLIESKDLICAADRENMRVQCYSAGLKVTSKSGKLIKTIKDEKF-GPVYAVGFNKL-NNLMYVVS-DMVDDTDRSRVFIYNWELDMVIGVMDYSGTNGFGMAHTIDVCPRG 1103
            V +WP   L   LGQVSGL+      L IFHR D   D  SF+ + +YQ  S GPI++S I+ ++      +++   G N+FYLPHGI AD+ ++   TD+A HQVL++  +  ++  L LGE FTPG+D++HFC+PT  A+    G +FV+DGYCN+RI+KF   GK++ ++G    + + ++R  IPH L  +  +  +C ADREN R+QC+ A       +G+ +K IK E+F G V+A+ ++   + L+Y V+ D    +   R F+ N+    ++          F M H +   P G
Sbjct:  413 VTDWPEGNL--QLGQVSGLALDSDSNLVIFHRGDHHWDLDSFDGRARYQHRSLGPIQQSAILVVDPAK--GRILKASGRNMFYLPHGITADRDNNYWVTDVALHQVLKVSSDGRDRTLLALGEAFTPGSDSSHFCQPTDVAIDPHTGNVFVSDGYCNARILKFSADGKYLSQWGAGSLDRRQRARFQIPHSLAFLSDRREVCVADRENGRIQCFIA------DTGEFVKEIKKEEFGGKVFAISYSPAGDGLIYAVNGDSPYHSAPLRGFVINYTSREILDTFSPKRKQDFKMPHDLVGGPDG 705
[Close]
BLAST of Peptidyl-glycine alpha-amidating monooxygenase vs. Ensembl Medaka
Match: pam (peptidylglycine alpha-amidating monooxygenase [Source:NCBI gene;Acc:101164528])

HSP 1 Score: 186.422 bits (472), Expect = 1.790e-50
Identity = 112/303 (36.96%), Postives = 174/303 (57.43%), Query Frame = 3 
Query:  225 VPNWPSSKLLDYLGQVSGLSFCPKGYLYIFHRADVEMDERSFNNKNQYQKLSDGPIKESTXXXXXXXXXXAKVVGEFGSNLFYLPHGIFADK-HHMIATDLARHQVLRIPHNS-NKPDLILGEIFTPGNDANHFCKPTH-AVAAEDGTIFVADGYCNSRIVKFDKHGKFIGEFG----NAKDKSRLSIPHHLVLIESKDLICAADRENMRVQCYSAGLKVTSKSGKLIKTIKDEKF-GPVYAVGFNKL-NNLMYVVS-DMVDDTDRSRVFIYNWELDMVIGVMDYSGTNGFGMAHTIDVCPRG 1103
            V +WP   L   LGQVSGL+      L IFHR D   D  SF+ + +YQ  S GPI++S I+ ++      +++   G N+FYLPHGI AD+ ++   TD+A HQVL++  +  ++  L LGE FTPG+D++HFC+PT  A+    G +FV+DGYCN+RI+KF   GK++ ++G    + + ++R  IPH L  +  +  +C ADREN R+QC+ A       +G+ +K IK E+F G V+A+ ++   + L+Y V+ D    +   R F+ N+    ++          F M H +   P G
Sbjct:  384 VTDWPEGNL--QLGQVSGLALDSDSNLVIFHRGDHHWDLDSFDGRARYQHRSLGPIQQSAILVVDPAK--GRILKASGRNMFYLPHGITADRDNNYWVTDVALHQVLKVSSDGRDRTLLALGEAFTPGSDSSHFCQPTDVAIDPHTGNVFVSDGYCNARILKFSADGKYLSQWGAGSLDRRQRARFQIPHSLAFLSDRREVCVADRENGRIQCFIA------DTGEFVKEIKKEEFGGKVFAISYSPAGDGLIYAVNGDSPYHSAPLRGFVINYTSREILDTFSPKRKQDFKMPHDLVGGPDG 676
[Close]
BLAST of Peptidyl-glycine alpha-amidating monooxygenase vs. Ensembl Medaka
Match: pam (peptidylglycine alpha-amidating monooxygenase [Source:NCBI gene;Acc:101164528])

HSP 1 Score: 186.037 bits (471), Expect = 2.030e-50
Identity = 112/303 (36.96%), Postives = 174/303 (57.43%), Query Frame = 3 
Query:  225 VPNWPSSKLLDYLGQVSGLSFCPKGYLYIFHRADVEMDERSFNNKNQYQKLSDGPIKESTXXXXXXXXXXAKVVGEFGSNLFYLPHGIFADK-HHMIATDLARHQVLRIPHNS-NKPDLILGEIFTPGNDANHFCKPTH-AVAAEDGTIFVADGYCNSRIVKFDKHGKFIGEFG----NAKDKSRLSIPHHLVLIESKDLICAADRENMRVQCYSAGLKVTSKSGKLIKTIKDEKF-GPVYAVGFNKL-NNLMYVVS-DMVDDTDRSRVFIYNWELDMVIGVMDYSGTNGFGMAHTIDVCPRG 1103
            V +WP   L   LGQVSGL+      L IFHR D   D  SF+ + +YQ  S GPI++S I+ ++      +++   G N+FYLPHGI AD+ ++   TD+A HQVL++  +  ++  L LGE FTPG+D++HFC+PT  A+    G +FV+DGYCN+RI+KF   GK++ ++G    + + ++R  IPH L  +  +  +C ADREN R+QC+ A       +G+ +K IK E+F G V+A+ ++   + L+Y V+ D    +   R F+ N+    ++          F M H +   P G
Sbjct:  367 VTDWPEGNL--QLGQVSGLALDSDSNLVIFHRGDHHWDLDSFDGRARYQHRSLGPIQQSAILVVDPAK--GRILKASGRNMFYLPHGITADRDNNYWVTDVALHQVLKVSSDGRDRTLLALGEAFTPGSDSSHFCQPTDVAIDPHTGNVFVSDGYCNARILKFSADGKYLSQWGAGSLDRRQRARFQIPHSLAFLSDRREVCVADRENGRIQCFIA------DTGEFVKEIKKEEFGGKVFAISYSPAGDGLIYAVNGDSPYHSAPLRGFVINYTSREILDTFSPKRKQDFKMPHDLVGGPDG 659
[Close]
BLAST of Peptidyl-glycine alpha-amidating monooxygenase vs. Planmine SMEST
Match: SMESG000042480.1 (SMESG000042480.1)

HSP 1 Score: 764.607 bits (1973), Expect = 0.000e+0
Identity = 378/378 (100.00%), Postives = 378/378 (100.00%), Query Frame = 3 
Query:  111 CSPIDTAVNELNQLQKSPVGKVAVENKPFKVTLENANLVPNWPSSKLLDYLGQVSGLSFCPKGYLYIFHRADVEMDERSFNNKNQYQKLSDGPIKESTXXXXXXXXXXAKVVGEFGSNLFYLPHGIFADKHHMIATDLARHQVLRIPHNSNKPDLILGEIFTPGNDANHFCKPTHAVAAEDGTIFVADGYCNSRIVKFDKHGKFIGEFGNAKDKSRLSIPHHLVLIESKDLICAADRENMRVQCYSAGLKVTSKSGKLIKTIKDEKFGPVYAVGFNKLNNLMYVVSDMVDDTDRSRVFIYNWELDMVIGVMDYSGTNGFGMAHTIDVCPRGHCVAIGSLTKECPSDLINCLERGNDEEDFQLRNVWLYQLLDAKLDLA 1244
            CSPIDTAVNELNQLQKSPVGKVAVENKPFKVTLENANLVPNWPSSKLLDYLGQVSGLSFCPKGYLYIFHRADVEMDERSFNNKNQYQKLSDGPIKESTIIKINNDIDNAKVVGEFGSNLFYLPHGIFADKHHMIATDLARHQVLRIPHNSNKPDLILGEIFTPGNDANHFCKPTHAVAAEDGTIFVADGYCNSRIVKFDKHGKFIGEFGNAKDKSRLSIPHHLVLIESKDLICAADRENMRVQCYSAGLKVTSKSGKLIKTIKDEKFGPVYAVGFNKLNNLMYVVSDMVDDTDRSRVFIYNWELDMVIGVMDYSGTNGFGMAHTIDVCPRGHCVAIGSLTKECPSDLINCLERGNDEEDFQLRNVWLYQLLDAKLDLA
Sbjct:   17 CSPIDTAVNELNQLQKSPVGKVAVENKPFKVTLENANLVPNWPSSKLLDYLGQVSGLSFCPKGYLYIFHRADVEMDERSFNNKNQYQKLSDGPIKESTIIKINNDIDNAKVVGEFGSNLFYLPHGIFADKHHMIATDLARHQVLRIPHNSNKPDLILGEIFTPGNDANHFCKPTHAVAAEDGTIFVADGYCNSRIVKFDKHGKFIGEFGNAKDKSRLSIPHHLVLIESKDLICAADRENMRVQCYSAGLKVTSKSGKLIKTIKDEKFGPVYAVGFNKLNNLMYVVSDMVDDTDRSRVFIYNWELDMVIGVMDYSGTNGFGMAHTIDVCPRGHCVAIGSLTKECPSDLINCLERGNDEEDFQLRNVWLYQLLDAKLDLA 394
[Close]
BLAST of Peptidyl-glycine alpha-amidating monooxygenase vs. Planmine SMEST
Match: SMESG000042480.1 (SMESG000042480.1)

HSP 1 Score: 764.222 bits (1972), Expect = 0.000e+0
Identity = 378/378 (100.00%), Postives = 378/378 (100.00%), Query Frame = 3 
Query:  111 CSPIDTAVNELNQLQKSPVGKVAVENKPFKVTLENANLVPNWPSSKLLDYLGQVSGLSFCPKGYLYIFHRADVEMDERSFNNKNQYQKLSDGPIKESTXXXXXXXXXXAKVVGEFGSNLFYLPHGIFADKHHMIATDLARHQVLRIPHNSNKPDLILGEIFTPGNDANHFCKPTHAVAAEDGTIFVADGYCNSRIVKFDKHGKFIGEFGNAKDKSRLSIPHHLVLIESKDLICAADRENMRVQCYSAGLKVTSKSGKLIKTIKDEKFGPVYAVGFNKLNNLMYVVSDMVDDTDRSRVFIYNWELDMVIGVMDYSGTNGFGMAHTIDVCPRGHCVAIGSLTKECPSDLINCLERGNDEEDFQLRNVWLYQLLDAKLDLA 1244
            CSPIDTAVNELNQLQKSPVGKVAVENKPFKVTLENANLVPNWPSSKLLDYLGQVSGLSFCPKGYLYIFHRADVEMDERSFNNKNQYQKLSDGPIKESTIIKINNDIDNAKVVGEFGSNLFYLPHGIFADKHHMIATDLARHQVLRIPHNSNKPDLILGEIFTPGNDANHFCKPTHAVAAEDGTIFVADGYCNSRIVKFDKHGKFIGEFGNAKDKSRLSIPHHLVLIESKDLICAADRENMRVQCYSAGLKVTSKSGKLIKTIKDEKFGPVYAVGFNKLNNLMYVVSDMVDDTDRSRVFIYNWELDMVIGVMDYSGTNGFGMAHTIDVCPRGHCVAIGSLTKECPSDLINCLERGNDEEDFQLRNVWLYQLLDAKLDLA
Sbjct:   18 CSPIDTAVNELNQLQKSPVGKVAVENKPFKVTLENANLVPNWPSSKLLDYLGQVSGLSFCPKGYLYIFHRADVEMDERSFNNKNQYQKLSDGPIKESTIIKINNDIDNAKVVGEFGSNLFYLPHGIFADKHHMIATDLARHQVLRIPHNSNKPDLILGEIFTPGNDANHFCKPTHAVAAEDGTIFVADGYCNSRIVKFDKHGKFIGEFGNAKDKSRLSIPHHLVLIESKDLICAADRENMRVQCYSAGLKVTSKSGKLIKTIKDEKFGPVYAVGFNKLNNLMYVVSDMVDDTDRSRVFIYNWELDMVIGVMDYSGTNGFGMAHTIDVCPRGHCVAIGSLTKECPSDLINCLERGNDEEDFQLRNVWLYQLLDAKLDLA 395
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BLAST of Peptidyl-glycine alpha-amidating monooxygenase vs. Planmine SMEST
Match: SMESG000057300.1 (SMESG000057300.1)

HSP 1 Score: 122.865 bits (307), Expect = 2.480e-29
Identity = 98/299 (32.78%), Postives = 148/299 (49.50%), Query Frame = 3 
Query:  204 TLENAN-------LVPNWPSSKLLDYLGQVSGLS-FCPKGY-----LYIFHRADVEMDERSFNNKNQYQKLSDGPIKESTXXXXXXXXXXAKVVGEFGSNLFYLPHGIFA--DKHHMIATDLARHQVLRIPHNSNK------PDLILGEIFTPGNDANHFCKPTHAVAAEDGTIFVADGYCNSRIVKFDKHGKFIGEFGNAKDKSRLSIPHHLVLIE------SKDLICAADRENMRVQ--CYSAGLKVTSKSGKLIKTIKDEKFGPVYAVGFNKLNNLMYVVSDMVDDTDRSRVFIYN 1013
            TL+N N       +  NW  +K L   G+VSG+S    K Y     + + HR      ERSF  K+ YQ+  D PI + TI++++       V+ E    +FY+PHGI A  D  ++  TD+A HQV+R     +       P ++LG+ F PG D NHFCKP+       G IFVADGYCN+R+V F  +G +I E+   + +  + I H + + E      SK+++  ADREN ++    Y   +K T    K +          +Y + +N  N L+Y ++   D   R   F +N
Sbjct:  325 TLQNYNFDIDVLKMDKNWKVNKKL---GEVSGVSILLTKQYKLGYSVLVLHRGSHAWTERSFI-KDVYQEDLDSPISDYTIVEVDPVS--GNVLREAARGIFYMPHGITATKDGKYLWITDVAFHQVMRFNVRDDSKLIDKTPSIVLGKRFIPGRDMNHFCKPSQVAVDSRGYIFVADGYCNNRVVCFYPNGTYIEEW---QSQDPMFIVHSITIKEDESGDISKNIVWVADRENRKIIGFGYDGIIKFTHIFRKSLS---------IYGIKYNPKNQLIYGITS--DGDIRGSSFTFN 603
The following BLAST results are available for this feature:
BLAST of Peptidyl-glycine alpha-amidating monooxygenase vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
PAM7.003e-4839.53peptidylglycine alpha-amidating monooxygenase [Sou... [more]
PAM2.419e-4739.53peptidylglycine alpha-amidating monooxygenase [Sou... [more]
PAM2.455e-4739.53peptidylglycine alpha-amidating monooxygenase [Sou... [more]
PAM2.509e-4739.53peptidylglycine alpha-amidating monooxygenase [Sou... [more]
PAM2.565e-4739.53peptidylglycine alpha-amidating monooxygenase [Sou... [more]
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BLAST of Peptidyl-glycine alpha-amidating monooxygenase vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 3
Match NameE-valueIdentityDescription
pgal-13.804e-4843.04Probable peptidyl-alpha-hydroxyglycine alpha-amida... [more]
pgal-13.804e-4843.04Probable peptidyl-alpha-hydroxyglycine alpha-amida... [more]
pamn-12.562e-3132.04Probable peptidyl-glycine alpha-amidating monooxyg... [more]
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BLAST of Peptidyl-glycine alpha-amidating monooxygenase vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Pal23.996e-5341.18gene:FBgn0262728 transcript:FBtr0089500[more]
Pal23.996e-5341.18gene:FBgn0262728 transcript:FBtr0346652[more]
Pal23.996e-5341.18gene:FBgn0262728 transcript:FBtr0301509[more]
Pal19.568e-4340.28gene:FBgn0283510 transcript:FBtr0339422[more]
Pal12.264e-4240.28gene:FBgn0283510 transcript:FBtr0339423[more]
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BLAST of Peptidyl-glycine alpha-amidating monooxygenase vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 4
Match NameE-valueIdentityDescription
pam5.454e-4641.02peptidylglycine alpha-amidating monooxygenase [Sou... [more]
pam1.397e-4541.02peptidylglycine alpha-amidating monooxygenase [Sou... [more]
pam4.405e-4540.68peptidylglycine alpha-amidating monooxygenase [Sou... [more]
pam2.643e-1244.34peptidylglycine alpha-amidating monooxygenase [Sou... [more]
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BLAST of Peptidyl-glycine alpha-amidating monooxygenase vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
pam6.785e-4839.72peptidylglycine alpha-amidating monooxygenase [Sou... [more]
pam6.823e-4839.72peptidylglycine alpha-amidating monooxygenase [Sou... [more]
pam6.873e-4839.72peptidylglycine alpha-amidating monooxygenase [Sou... [more]
pam6.886e-4839.72peptidylglycine alpha-amidating monooxygenase [Sou... [more]
pam7.057e-4839.58peptidylglycine alpha-amidating monooxygenase [Sou... [more]
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BLAST of Peptidyl-glycine alpha-amidating monooxygenase vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 4
Match NameE-valueIdentityDescription
Pam9.847e-4634.87peptidylglycine alpha-amidating monooxygenase [Sou... [more]
Pam1.135e-4534.87peptidylglycine alpha-amidating monooxygenase [Sou... [more]
Pam1.226e-4534.87peptidylglycine alpha-amidating monooxygenase [Sou... [more]
Pam6.494e-1839.62peptidylglycine alpha-amidating monooxygenase [Sou... [more]
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BLAST of Peptidyl-glycine alpha-amidating monooxygenase vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q9W1L5|PAL2_DROME4.006e-5241.18Peptidyl-alpha-hydroxyglycine alpha-amidating lyas... [more]
sp|P12890|AMDB_XENLA1.637e-4842.29Peptidyl-glycine alpha-amidating monooxygenase B O... [more]
sp|P08478|AMDA_XENLA1.472e-4741.50Peptidyl-glycine alpha-amidating monooxygenase A O... [more]
sp|P91268|PGAL_CAEEL4.839e-4743.04Probable peptidyl-alpha-hydroxyglycine alpha-amida... [more]
sp|P19021|AMD_HUMAN1.161e-4639.53Peptidyl-glycine alpha-amidating monooxygenase OS=... [more]
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BLAST of Peptidyl-glycine alpha-amidating monooxygenase vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A267FBA01.022e-7140.11Uncharacterized protein OS=Macrostomum lignano OX=... [more]
A0A1I8HRY23.194e-7140.28Uncharacterized protein OS=Macrostomum lignano OX=... [more]
A0A267GR201.347e-6646.88Uncharacterized protein OS=Macrostomum lignano OX=... [more]
A0A1I8IUF66.276e-6339.27Uncharacterized protein OS=Macrostomum lignano OX=... [more]
A0A1W4WYG36.338e-5846.84peptidyl-alpha-hydroxyglycine alpha-amidating lyas... [more]
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BLAST of Peptidyl-glycine alpha-amidating monooxygenase vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 3
Match NameE-valueIdentityDescription
pam3.728e-5239.27peptidylglycine alpha-amidating monooxygenase [Sou... [more]
pam3.880e-5240.26peptidylglycine alpha-amidating monooxygenase [Sou... [more]
pam4.472e-5240.13peptidylglycine alpha-amidating monooxygenase [Sou... [more]
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BLAST of Peptidyl-glycine alpha-amidating monooxygenase vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 3
Match NameE-valueIdentityDescription
ENSPMAT00000003037.14.794e-3937.80pep scaffold:Pmarinus_7.0:GL480308:28740:39707:1 g... [more]
NHLRC33.381e-728.85NHL repeat containing 3 [Source:HGNC Symbol;Acc:HG... [more]
ENSPMAT00000005035.13.740e-631.54pep scaffold:Pmarinus_7.0:GL476697:205350:209715:-... [more]
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BLAST of Peptidyl-glycine alpha-amidating monooxygenase vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Peptidyl-glycine alpha-amidating monooxygenase vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 2
Match NameE-valueIdentityDescription
EDO421392.441e-4136.30Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO298519.319e-928.76Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Peptidyl-glycine alpha-amidating monooxygenase vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
pam1.880e-5136.62peptidylglycine alpha-amidating monooxygenase [Sou... [more]
pam2.395e-5136.62peptidylglycine alpha-amidating monooxygenase [Sou... [more]
pam1.551e-5036.96peptidylglycine alpha-amidating monooxygenase [Sou... [more]
pam1.790e-5036.96peptidylglycine alpha-amidating monooxygenase [Sou... [more]
pam2.030e-5036.96peptidylglycine alpha-amidating monooxygenase [Sou... [more]
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BLAST of Peptidyl-glycine alpha-amidating monooxygenase vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 3
Match NameE-valueIdentityDescription
SMESG000042480.10.000e+0100.00SMESG000042480.1[more]
SMESG000042480.10.000e+0100.00SMESG000042480.1[more]
SMESG000057300.12.480e-2932.78SMESG000057300.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30017749 ID=SMED30017749|Name=Peptidyl-glycine alpha-amidating monooxygenase|organism=Schmidtea mediterranea sexual|type=transcript|length=1524bp
AAAACTATTAATTATATACTTGTATAAATAACTCCAATCCACGATAATTC
TAATTATAAATGATGATTTCTATTTTTATTATTATATCAAATATTTTATT
TTTCATTTCCTGTTCACCAATAGATACTGCTGTTAATGAACTGAATCAAC
TTCAGAAATCCCCAGTTGGAAAAGTTGCAGTTGAAAACAAACCGTTCAAA
GTTACGTTAGAAAATGCTAATCTTGTACCAAACTGGCCATCATCAAAACT
CTTGGATTACCTAGGTCAAGTTTCGGGTCTTTCTTTTTGCCCCAAAGGAT
ATTTGTATATTTTTCACAGAGCTGATGTAGAAATGGATGAGAGATCATTC
AACAATAAAAATCAGTACCAAAAACTCTCCGATGGGCCGATCAAAGAAAG
CACAATAATAAAGATAAACAATGACATTGATAACGCGAAAGTGGTGGGAG
AATTCGGTTCAAATCTGTTTTATTTACCTCACGGAATATTTGCTGATAAA
CATCATATGATTGCAACAGATCTCGCTAGGCATCAAGTTCTGCGCATTCC
TCACAATTCCAATAAACCGGATTTAATCCTCGGGGAAATTTTCACACCTG
GAAATGATGCGAATCATTTTTGTAAACCGACTCATGCCGTTGCCGCTGAA
GACGGCACGATTTTTGTAGCGGATGGATATTGCAATTCGAGAATTGTGAA
ATTTGACAAGCACGGAAAATTCATTGGAGAATTCGGAAACGCAAAAGATA
AATCTCGTCTATCTATACCACATCACCTGGTGCTAATCGAATCAAAAGAT
TTGATATGTGCTGCTGATAGGGAAAATATGAGAGTTCAGTGCTATTCAGC
AGGACTCAAAGTTACTTCAAAATCAGGGAAATTAATAAAAACTATCAAAG
ATGAAAAGTTTGGACCCGTTTACGCAGTTGGTTTCAATAAACTAAACAAT
TTGATGTATGTTGTAAGTGATATGGTGGATGATACTGACAGATCTAGAGT
TTTTATATACAACTGGGAACTGGATATGGTTATTGGAGTAATGGATTATT
CGGGAACAAATGGATTTGGAATGGCTCATACAATCGACGTGTGTCCAAGA
GGACATTGTGTAGCCATTGGAAGCTTGACTAAAGAATGTCCATCAGATCT
AATTAATTGTTTGGAGCGAGGCAATGACGAGGAAGATTTTCAATTAAGAA
ACGTGTGGCTTTATCAATTATTGGATGCAAAATTAGATTTGGCATAATCG
AGAAGAAATTTCCATCTGAATATCCAGTTAGATTGTGTCCCATGTTTCCG
TCATAACATCAGTAGTCCTATGTCATTATTTTATGCCCATATCATTCGAC
AAAAGATAATTGTTAACTTTGAAATTCTGCTTATAATACAGAAAACTTGC
AATTTTATCATTTGTTTTAATGATAGAAATCAACATATTGCAAAGCGATA
TTATCATAAATATTCGTCAGTTTGAGTTTTTCATTAATTTAATCAGTTTG
AAACTATTTTTTCGTCGGATTTGT
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protein sequence of SMED30017749-orf-1

>SMED30017749-orf-1 ID=SMED30017749-orf-1|Name=SMED30017749-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=396bp
MMISIFIIISNILFFISCSPIDTAVNELNQLQKSPVGKVAVENKPFKVTL
ENANLVPNWPSSKLLDYLGQVSGLSFCPKGYLYIFHRADVEMDERSFNNK
NQYQKLSDGPIKESTIIKINNDIDNAKVVGEFGSNLFYLPHGIFADKHHM
IATDLARHQVLRIPHNSNKPDLILGEIFTPGNDANHFCKPTHAVAAEDGT
IFVADGYCNSRIVKFDKHGKFIGEFGNAKDKSRLSIPHHLVLIESKDLIC
AADRENMRVQCYSAGLKVTSKSGKLIKTIKDEKFGPVYAVGFNKLNNLMY
VVSDMVDDTDRSRVFIYNWELDMVIGVMDYSGTNGFGMAHTIDVCPRGHC
VAIGSLTKECPSDLINCLERGNDEEDFQLRNVWLYQLLDAKLDLA*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000099neuron
PLANA:0000418head
PLANA:0000463cholinergic neuron
Vocabulary: INTERPRO
TermDefinition
IPR0110426-blade_b-propeller_TolB-like
IPR013017NHL_repeat_subgr
Vocabulary: molecular function
TermDefinition
GO:0003824catalytic activity
GO:0004497monooxygenase activity
Vocabulary: biological process
TermDefinition
GO:0006518peptide metabolic process
GO:0055114oxidation-reduction process
Vocabulary: cellular component
TermDefinition
GO:0016020membrane
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR011042Six-bladed beta-propeller, TolB-likeGENE3DG3DSA:2.120.10.30coord: 46..362
e-value: 6.4E-79
score: 267.5
NoneNo IPR availablePANTHERPTHR10680PEPTIDYL-GLYCINE ALPHA-AMIDATING MONOOXYGENASEcoord: 61..356
NoneNo IPR availablePANTHERPTHR10680:SF14PEPTIDYL-GLYCINE ALPHA-AMIDATING MONOOXYGENASEcoord: 61..356
NoneNo IPR availableCDDcd14958NHL_PAL_likecoord: 56..349
e-value: 2.22879E-85
score: 259.888
NoneNo IPR availableSIGNALP_EUKSignalP-noTMSignalP-noTMcoord: 1..18
score: 0.776
NoneNo IPR availableSUPERFAMILYSSF63829Calcium-dependent phosphotriesterasecoord: 57..355
IPR013017NHL repeat, subgroupPROSITEPS51125NHLcoord: 252..265
score: 6.517
IPR013017NHL repeat, subgroupPROSITEPS51125NHLcoord: 126..143
score: 4.42
IPR013017NHL repeat, subgroupPROSITEPS51125NHLcoord: 179..218
score: 9.91