Ras-related protein Rab-2A

Overview
NameRas-related protein Rab-2A
Smed IDSMED30017717
Length (bp)1052
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Ras-related protein Rab-2A (SMED30017717) t-SNE clustered cells

Violin plots show distribution of expression levels for Ras-related protein Rab-2A (SMED30017717) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Ras-related protein Rab-2A (SMED30017717) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Ras-related protein Rab-2A (SMED30017717) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30017717

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 3

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
protonephridiaSMED30017717SMESG000076159.1 dd_Smed_v4_1113_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
gutSMED30017717SMESG000076159.1 dd_Smed_v4_1113_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30017717SMESG000076159.1 dd_Smed_v4_1113_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Ras-related protein Rab-2A vs. Ensembl Human
Match: RAB2A (RAB2A, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:9763])

HSP 1 Score: 383.645 bits (984), Expect = 1.134e-134
Identity = 179/197 (90.86%), Postives = 192/197 (97.46%), Query Frame = 2 
Query:   56 MSYSYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQVKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRETFNHLTTWLEDARQHSSSNMVIMLIGNKSDLEARRDVKREEGEAFAREHGLVFMETSAKTAANVEEAFINTAKAIYEKIQEGVLDINNEANGIKLGPQHTPSGST 646
            M+Y+YLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQ+KLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRR+TFNHLTTWLEDARQHS+SNMVIMLIGNKSDLE+RR+VK+EEGEAFAREHGL+FMETSAKTA+NVEEAFINTAK IYEKIQEGV DINNEANGIK+GPQH  + +T
Sbjct:    1 MAYAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRDTFNHLTTWLEDARQHSNSNMVIMLIGNKSDLESRREVKKEEGEAFAREHGLIFMETSAKTASNVEEAFINTAKEIYEKIQEGVFDINNEANGIKIGPQHAATNAT 197
[Close]
BLAST of Ras-related protein Rab-2A vs. Ensembl Human
Match: RAB2B (RAB2B, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:20246])

HSP 1 Score: 380.563 bits (976), Expect = 1.691e-133
Identity = 180/216 (83.33%), Postives = 195/216 (90.28%), Query Frame = 2 
Query:   56 MSYSYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQVKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRETFNHLTTWLEDARQHSSSNMVIMLIGNKSDLEARRDVKREEGEAFAREHGLVFMETSAKTAANVEEAFINTAKAIYEKIQEGVLDINNEANGIKLGPQHTPSGSTAGLGQNRS-----SSGGCC 688
            M+Y+YLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARM+ IDGKQ+KLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRETFNHLT+WLEDARQHSSSNMVIMLIGNKSDLE+RRDVKREEGEAFAREHGL+FMETSAKTA NVEEAFINTAK IY KIQ+G+ D++NEANGIK+GPQ + S S       R+     S+ GCC
Sbjct:    1 MTYAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMVNIDGKQIKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRETFNHLTSWLEDARQHSSSNMVIMLIGNKSDLESRRDVKREEGEAFAREHGLIFMETSAKTACNVEEAFINTAKEIYRKIQQGLFDVHNEANGIKIGPQQSISTSVGPSASQRNSRDIGSNSGCC 216
[Close]
BLAST of Ras-related protein Rab-2A vs. Ensembl Human
Match: RAB2B (RAB2B, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:20246])

HSP 1 Score: 379.793 bits (974), Expect = 3.558e-133
Identity = 179/206 (86.89%), Postives = 192/206 (93.20%), Query Frame = 2 
Query:   56 MSYSYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQVKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRETFNHLTTWLEDARQHSSSNMVIMLIGNKSDLEARRDVKREEGEAFAREHGLVFMETSAKTAANVEEAFINTAKAIYEKIQEGVLDINNEANGIKLGPQHT------PSGSTAGL 655
            M+Y+YLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARM+ IDGKQ+KLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRETFNHLT+WLEDARQHSSSNMVIMLIGNKSDLE+RRDVKREEGEAFAREHGL+FMETSAKTA NVEEAFINTAK IY KIQ+G+ D++NEANGIK+GPQ +      PS S AGL
Sbjct:    1 MTYAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMVNIDGKQIKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRETFNHLTSWLEDARQHSSSNMVIMLIGNKSDLESRRDVKREEGEAFAREHGLIFMETSAKTACNVEEAFINTAKEIYRKIQQGLFDVHNEANGIKIGPQQSISTSVGPSASHAGL 206
[Close]
BLAST of Ras-related protein Rab-2A vs. Ensembl Human
Match: RAB2A (RAB2A, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:9763])

HSP 1 Score: 318.161 bits (814), Expect = 3.330e-109
Identity = 155/197 (78.68%), Postives = 168/197 (85.28%), Query Frame = 2 
Query:   56 MSYSYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQVKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRETFNHLTTWLEDARQHSSSNMVIMLIGNKSDLEARRDVKREEGEAFAREHGLVFMETSAKTAANVEEAFINTAKAIYEKIQEGVLDINNEANGIKLGPQHTPSGST 646
            M+Y+YLFKYIIIGDTGV                        EFGARMITIDGKQ+KLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRR+TFNHLTTWLEDARQHS+SNMVIMLIGNKSDLE+RR+VK+EEGEAFAREHGL+FMETSAKTA+NVEEAFINTAK IYEKIQEGV DINNEANGIK+GPQH  + +T
Sbjct:    1 MAYAYLFKYIIIGDTGV------------------------EFGARMITIDGKQIKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRDTFNHLTTWLEDARQHSNSNMVIMLIGNKSDLESRREVKKEEGEAFAREHGLIFMETSAKTASNVEEAFINTAKEIYEKIQEGVFDINNEANGIKIGPQHAATNAT 173
[Close]
BLAST of Ras-related protein Rab-2A vs. Ensembl Human
Match: RAB14 (RAB14, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:16524])

HSP 1 Score: 264.233 bits (674), Expect = 1.407e-87
Identity = 124/209 (59.33%), Postives = 157/209 (75.12%), Query Frame = 2 
Query:   59 SYSYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQVKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRETFNHLTTWLEDARQHSSSNMVIMLIGNKSDLEARRDVKREEGEAFAREHGLVFMETSAKTAANVEEAFINTAKAIYEKIQEGVLDINNEANGIKLGPQHTPSGSTAGLGQNRSSSGGC 685
            +YSY+FKYIIIGD GVGKSCLL QFT+K+F      TIGVEFG R+I + G+++KLQIWDTAGQE FR++TRSYYRGAAGAL+VYDITRR T+NHL++WL DAR  ++ N VI+LIGNK+DLEA+RDV  EE + FA E+GL+F+E SAKT  NVE+AF+  AK IY+ IQ+G LD+N   +G++  P     G      Q +    GC
Sbjct:    7 NYSYIFKYIIIGDMGVGKSCLLHQFTEKKFMADCPHTIGVEFGTRIIEVSGQKIKLQIWDTAGQERFRAVTRSYYRGAAGALMVYDITRRSTYNHLSSWLTDARNLTNPNTVIILIGNKADLEAQRDVTYEEAKQFAEENGLLFLEASAKTGENVEDAFLEAAKKIYQNIQDGSLDLNAAESGVQHKPSAPQGGRLTSEPQPQREGCGC 215
[Close]
BLAST of Ras-related protein Rab-2A vs. Ensembl Celegans
Match: unc-108 (pep chromosome:WBcel235:I:3824947:3826514:1 gene:WBGene00006833.1 transcript:F53F10.4a.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:unc-108)

HSP 1 Score: 387.111 bits (993), Expect = 1.822e-136
Identity = 182/198 (91.92%), Postives = 192/198 (96.97%), Query Frame = 2 
Query:   56 MSYSYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQVKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRETFNHLTTWLEDARQHSSSNMVIMLIGNKSDLEARRDVKREEGEAFAREHGLVFMETSAKTAANVEEAFINTAKAIYEKIQEGVLDINNEANGIKLGPQHTPSGSTA 649
            MSY+YLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARM+TIDGKQ+KLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRR+TFNHLT+WLEDARQHS+SNMVIMLIGNKSDLEARR+VKREEGEAFAREHGLVFMETSAKTAANVEEAFI+TAK IY KIQEGV DINNEANGIKLGPQH+PS   +
Sbjct:    1 MSYAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMVTIDGKQIKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRDTFNHLTSWLEDARQHSNSNMVIMLIGNKSDLEARREVKREEGEAFAREHGLVFMETSAKTAANVEEAFIDTAKEIYRKIQEGVFDINNEANGIKLGPQHSPSSPNS 198
[Close]
BLAST of Ras-related protein Rab-2A vs. Ensembl Celegans
Match: unc-108 (pep chromosome:WBcel235:I:3822883:3826514:1 gene:WBGene00006833.1 transcript:F53F10.4b.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:unc-108)

HSP 1 Score: 387.111 bits (993), Expect = 2.484e-136
Identity = 182/198 (91.92%), Postives = 192/198 (96.97%), Query Frame = 2 
Query:   56 MSYSYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQVKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRETFNHLTTWLEDARQHSSSNMVIMLIGNKSDLEARRDVKREEGEAFAREHGLVFMETSAKTAANVEEAFINTAKAIYEKIQEGVLDINNEANGIKLGPQHTPSGSTA 649
            MSY+YLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARM+TIDGKQ+KLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRR+TFNHLT+WLEDARQHS+SNMVIMLIGNKSDLEARR+VKREEGEAFAREHGLVFMETSAKTAANVEEAFI+TAK IY KIQEGV DINNEANGIKLGPQH+PS   +
Sbjct:   10 MSYAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMVTIDGKQIKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRDTFNHLTSWLEDARQHSNSNMVIMLIGNKSDLEARREVKREEGEAFAREHGLVFMETSAKTAANVEEAFIDTAKEIYRKIQEGVFDINNEANGIKLGPQHSPSSPNS 207
[Close]
BLAST of Ras-related protein Rab-2A vs. Ensembl Celegans
Match: unc-108 (pep chromosome:WBcel235:I:3825124:3826514:1 gene:WBGene00006833.1 transcript:F53F10.4c.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:unc-108)

HSP 1 Score: 290.812 bits (743), Expect = 3.100e-99
Identity = 137/152 (90.13%), Postives = 146/152 (96.05%), Query Frame = 2 
Query:  194 MITIDGKQVKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRETFNHLTTWLEDARQHSSSNMVIMLIGNKSDLEARRDVKREEGEAFAREHGLVFMETSAKTAANVEEAFINTAKAIYEKIQEGVLDINNEANGIKLGPQHTPSGSTA 649
            M+TIDGKQ+KLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRR+TFNHLT+WLEDARQHS+SNMVIMLIGNKSDLEARR+VKREEGEAFAREHGLVFMETSAKTAANVEEAFI+TAK IY KIQEGV DINNEANGIKLGPQH+PS   +
Sbjct:    1 MVTIDGKQIKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRDTFNHLTSWLEDARQHSNSNMVIMLIGNKSDLEARREVKREEGEAFAREHGLVFMETSAKTAANVEEAFIDTAKEIYRKIQEGVFDINNEANGIKLGPQHSPSSPNS 152
[Close]
BLAST of Ras-related protein Rab-2A vs. Ensembl Celegans
Match: rab-14 (RAB family [Source:UniProtKB/TrEMBL;Acc:Q93874])

HSP 1 Score: 257.684 bits (657), Expect = 1.619e-85
Identity = 118/185 (63.78%), Postives = 149/185 (80.54%), Query Frame = 2 
Query:   59 SYSYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQVKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRETFNHLTTWLEDARQHSSSNMVIMLIGNKSDLEARRDVKREEGEAFAREHGLVFMETSAKTAANVEEAFINTAKAIYEKIQEGVLDINNEANGIK 613
            +YSY+FKYIIIGD GVGKSCLL QFT+K+F      TIGVEFG R+I + G+++KLQIWDTAGQE FR++TRSYYRGAAGAL+VYDITRR T+NHL++WL DA+  ++ N  I LIGNK+DLE +RDV  EE +AFA E+GL F+E SAKT +NVE+AF+ TAK IY+ IQ+G LD+N    G++
Sbjct:    7 NYSYIFKYIIIGDMGVGKSCLLHQFTEKKFMADCPHTIGVEFGTRIIEVSGQKIKLQIWDTAGQERFRAVTRSYYRGAAGALMVYDITRRSTYNHLSSWLADAKSLTNPNTAIFLIGNKADLEDQRDVPYEEAKAFAEENGLTFLECSAKTGSNVEDAFLETAKQIYQNIQDGSLDLNAADTGVQ 191
[Close]
BLAST of Ras-related protein Rab-2A vs. Ensembl Celegans
Match: rab-14 (RAB family [Source:UniProtKB/TrEMBL;Acc:Q93874])

HSP 1 Score: 257.684 bits (657), Expect = 1.619e-85
Identity = 118/185 (63.78%), Postives = 149/185 (80.54%), Query Frame = 2 
Query:   59 SYSYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQVKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRETFNHLTTWLEDARQHSSSNMVIMLIGNKSDLEARRDVKREEGEAFAREHGLVFMETSAKTAANVEEAFINTAKAIYEKIQEGVLDINNEANGIK 613
            +YSY+FKYIIIGD GVGKSCLL QFT+K+F      TIGVEFG R+I + G+++KLQIWDTAGQE FR++TRSYYRGAAGAL+VYDITRR T+NHL++WL DA+  ++ N  I LIGNK+DLE +RDV  EE +AFA E+GL F+E SAKT +NVE+AF+ TAK IY+ IQ+G LD+N    G++
Sbjct:    7 NYSYIFKYIIIGDMGVGKSCLLHQFTEKKFMADCPHTIGVEFGTRIIEVSGQKIKLQIWDTAGQERFRAVTRSYYRGAAGALMVYDITRRSTYNHLSSWLADAKSLTNPNTAIFLIGNKADLEDQRDVPYEEAKAFAEENGLTFLECSAKTGSNVEDAFLETAKQIYQNIQDGSLDLNAADTGVQ 191
[Close]
BLAST of Ras-related protein Rab-2A vs. Ensembl Fly
Match: Rab2 (gene:FBgn0014009 transcript:FBtr0336658)

HSP 1 Score: 384.03 bits (985), Expect = 3.256e-135
Identity = 183/213 (85.92%), Postives = 199/213 (93.43%), Query Frame = 2 
Query:   56 MSYSYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQVKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRETFNHLTTWLEDARQHSSSNMVIMLIGNKSDLEARRDVKREEGEAFAREHGLVFMETSAKTAANVEEAFINTAKAIYEKIQEGVLDINNEANGIKLGPQHTPSGST--AGLGQNRSSSGGCC 688
            MSY+YLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQ+KLQIWDTAGQE+FRSITRSYYRGAAGALLVYDITRRETFNHLTTWLEDARQHS+SNMVIMLIGNKSDL++RR+VK+EEGEAFAREHGLVFMETSA+TAANVEEAFINTAK IYEKIQEGV DINNEANGIK+G QH+P+  +     G   +++ GCC
Sbjct:    1 MSYAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIWDTAGQEAFRSITRSYYRGAAGALLVYDITRRETFNHLTTWLEDARQHSNSNMVIMLIGNKSDLDSRREVKKEEGEAFAREHGLVFMETSARTAANVEEAFINTAKEIYEKIQEGVFDINNEANGIKIGQQHSPTNPSLPGAGGAAGAANSGCC 213
[Close]
BLAST of Ras-related protein Rab-2A vs. Ensembl Fly
Match: Rab2 (gene:FBgn0014009 transcript:FBtr0086124)

HSP 1 Score: 384.03 bits (985), Expect = 3.256e-135
Identity = 183/213 (85.92%), Postives = 199/213 (93.43%), Query Frame = 2 
Query:   56 MSYSYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQVKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRETFNHLTTWLEDARQHSSSNMVIMLIGNKSDLEARRDVKREEGEAFAREHGLVFMETSAKTAANVEEAFINTAKAIYEKIQEGVLDINNEANGIKLGPQHTPSGST--AGLGQNRSSSGGCC 688
            MSY+YLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQ+KLQIWDTAGQE+FRSITRSYYRGAAGALLVYDITRRETFNHLTTWLEDARQHS+SNMVIMLIGNKSDL++RR+VK+EEGEAFAREHGLVFMETSA+TAANVEEAFINTAK IYEKIQEGV DINNEANGIK+G QH+P+  +     G   +++ GCC
Sbjct:    1 MSYAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIWDTAGQEAFRSITRSYYRGAAGALLVYDITRRETFNHLTTWLEDARQHSNSNMVIMLIGNKSDLDSRREVKKEEGEAFAREHGLVFMETSARTAANVEEAFINTAKEIYEKIQEGVFDINNEANGIKIGQQHSPTNPSLPGAGGAAGAANSGCC 213
[Close]
BLAST of Ras-related protein Rab-2A vs. Ensembl Fly
Match: Rab14 (gene:FBgn0015791 transcript:FBtr0343678)

HSP 1 Score: 256.144 bits (653), Expect = 9.882e-85
Identity = 121/193 (62.69%), Postives = 151/193 (78.24%), Query Frame = 2 
Query:   59 SYSYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQVKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRETFNHLTTWLEDARQHSSSNMVIMLIGNKSDLEARRDVKREEGEAFAREHGLVFMETSAKTAANVEEAFINTAKAIYEKIQEGVLDINNEANGIKLGPQHTPS 637
            +Y+Y+FKYIIIGD GVGKSCLL QFT+K+F      TIGVEFG R+I +D K++KLQIWDTAGQE FR++TRSYYRGAAGAL+VYDITRR T+NHL++WL D R  ++ + VI LIGNKSDLE+ R+V  EE + FA E+GL+F+E SA T  NVEEAF+ TA+ IY+ IQEG LD+N   +G+    QH PS
Sbjct:    7 NYNYIFKYIIIGDMGVGKSCLLHQFTEKKFMANCPHTIGVEFGTRIIEVDDKKIKLQIWDTAGQERFRAVTRSYYRGAAGALMVYDITRRSTYNHLSSWLTDTRNLTNPSTVIFLIGNKSDLESTREVTYEEAKEFADENGLMFLEASAMTGQNVEEAFLETARKIYQNIQEGRLDLNASESGV----QHRPS 195
[Close]
BLAST of Ras-related protein Rab-2A vs. Ensembl Fly
Match: Rab14 (gene:FBgn0015791 transcript:FBtr0080626)

HSP 1 Score: 256.144 bits (653), Expect = 9.882e-85
Identity = 121/193 (62.69%), Postives = 151/193 (78.24%), Query Frame = 2 
Query:   59 SYSYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQVKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRETFNHLTTWLEDARQHSSSNMVIMLIGNKSDLEARRDVKREEGEAFAREHGLVFMETSAKTAANVEEAFINTAKAIYEKIQEGVLDINNEANGIKLGPQHTPS 637
            +Y+Y+FKYIIIGD GVGKSCLL QFT+K+F      TIGVEFG R+I +D K++KLQIWDTAGQE FR++TRSYYRGAAGAL+VYDITRR T+NHL++WL D R  ++ + VI LIGNKSDLE+ R+V  EE + FA E+GL+F+E SA T  NVEEAF+ TA+ IY+ IQEG LD+N   +G+    QH PS
Sbjct:    7 NYNYIFKYIIIGDMGVGKSCLLHQFTEKKFMANCPHTIGVEFGTRIIEVDDKKIKLQIWDTAGQERFRAVTRSYYRGAAGALMVYDITRRSTYNHLSSWLTDTRNLTNPSTVIFLIGNKSDLESTREVTYEEAKEFADENGLMFLEASAMTGQNVEEAFLETARKIYQNIQEGRLDLNASESGV----QHRPS 195
[Close]
BLAST of Ras-related protein Rab-2A vs. Ensembl Fly
Match: Rab14 (gene:FBgn0015791 transcript:FBtr0080627)

HSP 1 Score: 256.144 bits (653), Expect = 1.947e-84
Identity = 125/205 (60.98%), Postives = 155/205 (75.61%), Query Frame = 2 
Query:   23 IIKFNKHT*A*MSYSYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQVKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRETFNHLTTWLEDARQHSSSNMVIMLIGNKSDLEARRDVKREEGEAFAREHGLVFMETSAKTAANVEEAFINTAKAIYEKIQEGVLDINNEANGIKLGPQHTPS 637
            I K    T A  +Y+Y+FKYIIIGD GVGKSCLL QFT+K+F      TIGVEFG R+I +D K++KLQIWDTAGQE FR++TRSYYRGAAGAL+VYDITRR T+NHL++WL D R  ++ + VI LIGNKSDLE+ R+V  EE + FA E+GL+F+E SA T  NVEEAF+ TA+ IY+ IQEG LD+N   +G+    QH PS
Sbjct:   19 IEKCPNMTAAPYNYNYIFKYIIIGDMGVGKSCLLHQFTEKKFMANCPHTIGVEFGTRIIEVDDKKIKLQIWDTAGQERFRAVTRSYYRGAAGALMVYDITRRSTYNHLSSWLTDTRNLTNPSTVIFLIGNKSDLESTREVTYEEAKEFADENGLMFLEASAMTGQNVEEAFLETARKIYQNIQEGRLDLNASESGV----QHRPS 219
[Close]
BLAST of Ras-related protein Rab-2A vs. Ensembl Zebrafish
Match: rab2a (RAB2A, member RAS oncogene family [Source:ZFIN;Acc:ZDB-GENE-011212-2])

HSP 1 Score: 385.185 bits (988), Expect = 1.525e-135
Identity = 180/197 (91.37%), Postives = 192/197 (97.46%), Query Frame = 2 
Query:   56 MSYSYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQVKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRETFNHLTTWLEDARQHSSSNMVIMLIGNKSDLEARRDVKREEGEAFAREHGLVFMETSAKTAANVEEAFINTAKAIYEKIQEGVLDINNEANGIKLGPQHTPSGST 646
            M+Y+YLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQ+KLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRR+TFNHLTTWLEDARQHS+SNMVIMLIGNKSDLE+RR+VK+EEGEAFAREHGL+FMETSAKTA+NVEEAFINTAK IYEKIQEGV DINNEANGIK+GPQH  + ST
Sbjct:    1 MAYAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRDTFNHLTTWLEDARQHSNSNMVIMLIGNKSDLESRREVKKEEGEAFAREHGLIFMETSAKTASNVEEAFINTAKEIYEKIQEGVFDINNEANGIKIGPQHAATNST 197
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BLAST of Ras-related protein Rab-2A vs. Ensembl Zebrafish
Match: rab14 (RAB14, member RAS oncogene family [Source:ZFIN;Acc:ZDB-GENE-030826-20])

HSP 1 Score: 264.233 bits (674), Expect = 8.295e-88
Identity = 124/198 (62.63%), Postives = 155/198 (78.28%), Query Frame = 2 
Query:   59 SYSYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQVKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRETFNHLTTWLEDARQHSSSNMVIMLIGNKSDLEARRDVKREEGEAFAREHGLVFMETSAKTAANVEEAFINTAKAIYEKIQEGVLDINNEANGIKLGPQHTPSGSTAG 652
            +YSY+FKYIIIGD GVGKSCLL QFT+K+F      TIGVEFG R+I + G++VKLQIWDTAGQE FR++TRSYYRGAAGAL+VYDITRR T+NHL++WL DAR  ++ N VI+LIGNK+DLEA+RDV  EE + FA E+GL+F+E SAKT  NVE+AF+  AK IY+ IQ+G LD+N   +G+    QH P+    G
Sbjct:    7 NYSYIFKYIIIGDMGVGKSCLLHQFTEKKFMADCPHTIGVEFGTRIIEVSGQKVKLQIWDTAGQERFRAVTRSYYRGAAGALMVYDITRRSTYNHLSSWLTDARNLTNPNTVIILIGNKADLEAQRDVTYEEAKQFAEENGLLFLEASAKTGENVEDAFLEAAKKIYQNIQDGSLDLNAAESGV----QHKPTAPQGG 200
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BLAST of Ras-related protein Rab-2A vs. Ensembl Zebrafish
Match: rab14l (RAB14, member RAS oncogene family, like [Source:ZFIN;Acc:ZDB-GENE-040426-1207])

HSP 1 Score: 263.077 bits (671), Expect = 2.518e-87
Identity = 123/198 (62.12%), Postives = 155/198 (78.28%), Query Frame = 2 
Query:   59 SYSYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQVKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRETFNHLTTWLEDARQHSSSNMVIMLIGNKSDLEARRDVKREEGEAFAREHGLVFMETSAKTAANVEEAFINTAKAIYEKIQEGVLDINNEANGIKLGPQHTPSGSTAG 652
            +YSY+FKYIIIGD GVGKSCLL QFT+K+F      TIGVEFG R++ + G+++KLQIWDTAGQE FR++TRSYYRGAAGAL+VYDITRR T+NHL++WL DAR  ++ N VI+LIGNK+DLEA+RDV  EE + FA E+GL+F+E SAKT  NVE+AF+  AK IY+ IQ+G LD+N   +G+    QH PS    G
Sbjct:    7 NYSYIFKYIIIGDMGVGKSCLLHQFTEKKFMADCPHTIGVEFGTRIMEVSGQKIKLQIWDTAGQERFRAVTRSYYRGAAGALMVYDITRRSTYNHLSSWLTDARNLTNPNTVIILIGNKADLEAQRDVTYEEAKQFAEENGLLFLEASAKTGENVEDAFLEAAKKIYQNIQDGSLDLNAAESGV----QHKPSAPQGG 200
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BLAST of Ras-related protein Rab-2A vs. Ensembl Zebrafish
Match: rab4b (RAB4B, member RAS oncogene family [Source:NCBI gene;Acc:445498])

HSP 1 Score: 231.106 bits (588), Expect = 7.842e-75
Identity = 114/202 (56.44%), Postives = 144/202 (71.29%), Query Frame = 2 
Query:   59 SYSYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQVKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRETFNHLTTWLEDARQHSSSNMVIMLIGNKSDLEARRDVKREEGEAFAREHGLVFMETSAKTAANVEEAFINTAKAIYEKIQEGVLDINNEANGIKLGPQ-----HTPSGSTA 649
            +Y +LFK+++IG  G GKSCLL QF + +F+   + TIGVEFG+R++ + GK VKLQIWDTAGQE FRS+TRSYYRGAAGALLVYDIT RET+N LT WL DAR  +S N+VI+L GNK DL+A R+V   E   FA+E+ L+F+ETSA T  NVEEAF+  A++I  KI+ G LD     +GI+ G         P GS A
Sbjct:    4 TYDFLFKFLVIGSAGTGKSCLLHQFIENKFKQDSNHTIGVEFGSRVVNVGGKTVKLQIWDTAGQERFRSVTRSYYRGAAGALLVYDITSRETYNALTNWLTDARTLASPNIVIILCGNKKDLDADREVTFLEASRFAQENELMFLETSALTGENVEEAFLKCARSILNKIESGELDPERMGSGIQYGDASLRQIRQPRGSAA 205
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BLAST of Ras-related protein Rab-2A vs. Ensembl Zebrafish
Match: rab4b (RAB4B, member RAS oncogene family [Source:NCBI gene;Acc:445498])

HSP 1 Score: 231.106 bits (588), Expect = 7.842e-75
Identity = 114/202 (56.44%), Postives = 144/202 (71.29%), Query Frame = 2 
Query:   59 SYSYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQVKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRETFNHLTTWLEDARQHSSSNMVIMLIGNKSDLEARRDVKREEGEAFAREHGLVFMETSAKTAANVEEAFINTAKAIYEKIQEGVLDINNEANGIKLGPQ-----HTPSGSTA 649
            +Y +LFK+++IG  G GKSCLL QF + +F+   + TIGVEFG+R++ + GK VKLQIWDTAGQE FRS+TRSYYRGAAGALLVYDIT RET+N LT WL DAR  +S N+VI+L GNK DL+A R+V   E   FA+E+ L+F+ETSA T  NVEEAF+  A++I  KI+ G LD     +GI+ G         P GS A
Sbjct:    4 TYDFLFKFLVIGSAGTGKSCLLHQFIENKFKQDSNHTIGVEFGSRVVNVGGKTVKLQIWDTAGQERFRSVTRSYYRGAAGALLVYDITSRETYNALTNWLTDARTLASPNIVIILCGNKKDLDADREVTFLEASRFAQENELMFLETSALTGENVEEAFLKCARSILNKIESGELDPERMGSGIQYGDASLRQIRQPRGSAA 205
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BLAST of Ras-related protein Rab-2A vs. Ensembl Xenopus
Match: RAB2A (RAB2A, member RAS oncogene family [Source:NCBI gene;Acc:100038062])

HSP 1 Score: 383.259 bits (983), Expect = 1.454e-134
Identity = 179/196 (91.33%), Postives = 191/196 (97.45%), Query Frame = 2 
Query:   56 MSYSYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQVKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRETFNHLTTWLEDARQHSSSNMVIMLIGNKSDLEARRDVKREEGEAFAREHGLVFMETSAKTAANVEEAFINTAKAIYEKIQEGVLDINNEANGIKLGPQHTPSGS 643
            M+Y+YLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQ+KLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRR+TFNHLTTWLEDARQHS+SNMVIMLI NKSDLE+RR+VK+EEGEAFAREHGL+FMETSAKTA+NVEEAFINTAK IYEKIQEGV DINNEANGIK+GPQH+  GS
Sbjct:    1 MAYAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRDTFNHLTTWLEDARQHSNSNMVIMLIANKSDLESRREVKKEEGEAFAREHGLIFMETSAKTASNVEEAFINTAKEIYEKIQEGVFDINNEANGIKIGPQHSTPGS 196
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BLAST of Ras-related protein Rab-2A vs. Ensembl Xenopus
Match: hus1 (HUS1 checkpoint clamp component [Source:Xenbase;Acc:XB-GENE-983295])

HSP 1 Score: 377.867 bits (969), Expect = 2.183e-132
Identity = 183/217 (84.33%), Postives = 199/217 (91.71%), Query Frame = 2 
Query:   56 MSYSYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQVKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRETFNHLTTWLEDARQHSSSNMVIMLIGNKSDLEARRDVKREEGEAFAREHGLVFMETSAKTAANVEEAFINTAKAIYEKIQEGVLDINNEANGIKLGPQHT---PSGSTAGLGQNRSSSG---GCC 688
            MSY+YLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMI IDGK +KLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRETF+HLT+WLEDARQHSSSNMVI+LIGNKSDLE+RRDV REEGEAFAREHGL+FMETSAKTAANVEEAFI+TAK IY+KIQ+G+ D+NNEANGIK+GPQ +   P GS  GL QN++  G   GCC
Sbjct:    1 MSYAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMINIDGKPIKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRETFSHLTSWLEDARQHSSSNMVIILIGNKSDLESRRDVSREEGEAFAREHGLIFMETSAKTAANVEEAFIDTAKEIYKKIQQGLFDVNNEANGIKVGPQQSINEPLGS--GLRQNQNEGGGTSGCC 215
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BLAST of Ras-related protein Rab-2A vs. Ensembl Xenopus
Match: RAB2A (RAB2A, member RAS oncogene family [Source:NCBI gene;Acc:100038062])

HSP 1 Score: 335.495 bits (859), Expect = 1.039e-115
Identity = 161/190 (84.74%), Postives = 173/190 (91.05%), Query Frame = 2 
Query:   62 YSYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQVKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRETFNHLTTWLEDARQHSSSNMVIMLIGNKSDLEARRDVKREEGEAFAREHGLVFMETSAKTAANVEEAFINTAKAIYEKIQEGVLDINNEANGIKLGPQHT 631
            Y Y +  ++I   GVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQ+KLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRR+TFNHLTTWLEDARQHS+SNMVIMLI NKSDLE+RR+VK+EEGEAFAREHGL+FMETSAKTA+NVEEAFINTAK IYEKIQEGV DINNE     L  QH+
Sbjct:    3 YCYCYFLLLIFYAGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRDTFNHLTTWLEDARQHSNSNMVIMLIANKSDLESRREVKKEEGEAFAREHGLIFMETSAKTASNVEEAFINTAKEIYEKIQEGVFDINNEVT--LLDQQHS 190
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BLAST of Ras-related protein Rab-2A vs. Ensembl Xenopus
Match: map4 (microtubule associated protein 4 [Source:Xenbase;Acc:XB-GENE-6259104])

HSP 1 Score: 226.868 bits (577), Expect = 4.666e-73
Identity = 110/193 (56.99%), Postives = 141/193 (73.06%), Query Frame = 2 
Query:   59 SYSYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQVKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRETFNHLTTWLEDARQHSSSNMVIMLIGNKSDLEARRDVKREEGEAFAREHGLVFMETSAKTAANVEEAFINTAKAIYEKIQEGVLDINNEANGIKLG---PQH 628
            +Y +LFK+++IG  G GKSCLL QF + +F+   + TIGVEFG+R++ + GK VKLQIWDTAGQE FRS+TRSYYRGAAGALLVYDI  RET+N LT WL DAR  +S N++I+L GNK DL+A R+V   E   FA+E+ L+F+ETSA T  NVEEAF+  A+ I  KI+ G LD     +GI+ G   P+H
Sbjct:    4 TYDFLFKFLVIGSAGTGKSCLLHQFIENKFKQDSNHTIGVEFGSRIVNVGGKSVKLQIWDTAGQERFRSVTRSYYRGAAGALLVYDIASRETYNALTNWLTDARTLASPNIIIILCGNKKDLDADREVTFLEASRFAQENELMFLETSALTGENVEEAFLKCARTILSKIESGELDPERMWSGIQYGDASPRH 196
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BLAST of Ras-related protein Rab-2A vs. Ensembl Xenopus
Match: rab14 (RAB14, member RAS oncogene family [Source:NCBI gene;Acc:493231])

HSP 1 Score: 223.402 bits (568), Expect = 5.826e-72
Identity = 111/209 (53.11%), Postives = 142/209 (67.94%), Query Frame = 2 
Query:   59 SYSYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQVKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRETFNHLTTWLEDARQHSSSNMVIMLIGNKSDLEARRDVKREEGEAFAREHGLVFMETSAKTAANVEEAFINTAKAIYEKIQEGVLDINNEANGIKLGPQHTPSGSTAGLGQNRSSSGGC 685
            +YSY+FKYIII    V   C                TIGVEFG R+I + G+++KLQIWDTAGQE FR++TRSYYRGAAGAL+VYDITRR T+NHL++WL DAR  ++ N VI+LIGNK+DLEA+RDV  EE + FA E+GL+F+E SAKT  NVE+AF+  AK IY+ IQ+G LD+N   +G++  P     G      Q +    GC
Sbjct:    7 NYSYIFKYIII----VMADC--------------PHTIGVEFGTRIIEVSGQKIKLQIWDTAGQERFRAVTRSYYRGAAGALMVYDITRRSTYNHLSSWLTDARNLTNPNTVIILIGNKADLEAQRDVTYEEAKQFAEENGLLFLEASAKTGENVEDAFLEAAKKIYQNIQDGSLDLNAAESGVQHKPSAPQGGRLTSEPQPQREGCGC 197
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BLAST of Ras-related protein Rab-2A vs. Ensembl Mouse
Match: Rab2a (RAB2A, member RAS oncogene family [Source:MGI Symbol;Acc:MGI:1928750])

HSP 1 Score: 384.03 bits (985), Expect = 5.483e-135
Identity = 179/199 (89.95%), Postives = 193/199 (96.98%), Query Frame = 2 
Query:   56 MSYSYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQVKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRETFNHLTTWLEDARQHSSSNMVIMLIGNKSDLEARRDVKREEGEAFAREHGLVFMETSAKTAANVEEAFINTAKAIYEKIQEGVLDINNEANGIKLGPQHTPSGSTAG 652
            M+Y+YLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQ+KLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRR+TFNHLTTWLEDARQHS+SNMVIMLIGNKSDLE+RR+VK+EEGEAFAREHGL+FMETSAKTA+NVEEAFINTAK IYEKIQEGV DINNEANGIK+GPQH  + ++ G
Sbjct:    1 MAYAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRDTFNHLTTWLEDARQHSNSNMVIMLIGNKSDLESRREVKKEEGEAFAREHGLIFMETSAKTASNVEEAFINTAKEIYEKIQEGVFDINNEANGIKIGPQHAATNASHG 199
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BLAST of Ras-related protein Rab-2A vs. Ensembl Mouse
Match: Rab2b (RAB2B, member RAS oncogene family [Source:MGI Symbol;Acc:MGI:1923588])

HSP 1 Score: 376.326 bits (965), Expect = 5.462e-132
Identity = 180/216 (83.33%), Postives = 195/216 (90.28%), Query Frame = 2 
Query:   56 MSYSYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQVKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRETFNHLTTWLEDARQHSSSNMVIMLIGNKSDLEARRDVKREEGEAFAREHGLVFMETSAKTAANVEEAFINTAKAIYEKIQEGVLDINNEANGIKLGPQHTPSGSTAGLG--QNRSSSG---GCC 688
            M+Y+YLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARM+ IDGKQ+KLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRETFNHLT+WLEDARQHSSSNMVIMLIGNKSDLE+RRDVKREEGEAFAREHGL+FMETSAKTA NVEEA+INTAK IY KIQ+G+ D++NEANGIK+GPQ + + S       QN S  G   GCC
Sbjct:    1 MTYAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMVNIDGKQIKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRETFNHLTSWLEDARQHSSSNMVIMLIGNKSDLESRRDVKREEGEAFAREHGLIFMETSAKTACNVEEAYINTAKEIYRKIQQGLFDVHNEANGIKIGPQQSITSSVGPCSPQQNVSDIGPDSGCC 216
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BLAST of Ras-related protein Rab-2A vs. Ensembl Mouse
Match: Rab2b (RAB2B, member RAS oncogene family [Source:MGI Symbol;Acc:MGI:1923588])

HSP 1 Score: 376.326 bits (965), Expect = 5.462e-132
Identity = 180/216 (83.33%), Postives = 195/216 (90.28%), Query Frame = 2 
Query:   56 MSYSYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQVKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRETFNHLTTWLEDARQHSSSNMVIMLIGNKSDLEARRDVKREEGEAFAREHGLVFMETSAKTAANVEEAFINTAKAIYEKIQEGVLDINNEANGIKLGPQHTPSGSTAGLG--QNRSSSG---GCC 688
            M+Y+YLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARM+ IDGKQ+KLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRETFNHLT+WLEDARQHSSSNMVIMLIGNKSDLE+RRDVKREEGEAFAREHGL+FMETSAKTA NVEEA+INTAK IY KIQ+G+ D++NEANGIK+GPQ + + S       QN S  G   GCC
Sbjct:    1 MTYAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMVNIDGKQIKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRETFNHLTSWLEDARQHSSSNMVIMLIGNKSDLESRRDVKREEGEAFAREHGLIFMETSAKTACNVEEAYINTAKEIYRKIQQGLFDVHNEANGIKIGPQQSITSSVGPCSPQQNVSDIGPDSGCC 216
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BLAST of Ras-related protein Rab-2A vs. Ensembl Mouse
Match: Rab2b (RAB2B, member RAS oncogene family [Source:MGI Symbol;Acc:MGI:1923588])

HSP 1 Score: 330.102 bits (845), Expect = 4.691e-114
Identity = 165/216 (76.39%), Postives = 175/216 (81.02%), Query Frame = 2 
Query:   56 MSYSYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQVKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRETFNHLTTWLEDARQHSSSNMVIMLIGNKSDLEARRDVKREEGEAFAREHGLVFMETSAKTAANVEEAFINTAKAIYEKIQEGVLDINNEANGIKLGPQHTPSGSTAGLG--QNRSSSG---GCC 688
            M+Y+YLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARM+ IDGKQ+KLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRETFNHLT+WLEDARQHSSSNMVIMLIGNKSDLE+RRDVKREEGEAFAREHGL+FMETSAKTA NVE                       EANGIK+GPQ + + S       QN S  G   GCC
Sbjct:    1 MTYAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMVNIDGKQIKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRETFNHLTSWLEDARQHSSSNMVIMLIGNKSDLESRRDVKREEGEAFAREHGLIFMETSAKTACNVE-----------------------EANGIKIGPQQSITSSVGPCSPQQNVSDIGPDSGCC 193
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BLAST of Ras-related protein Rab-2A vs. Ensembl Mouse
Match: Rab14 (RAB14, member RAS oncogene family [Source:MGI Symbol;Acc:MGI:1915615])

HSP 1 Score: 264.233 bits (674), Expect = 9.661e-88
Identity = 124/209 (59.33%), Postives = 157/209 (75.12%), Query Frame = 2 
Query:   59 SYSYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQVKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRETFNHLTTWLEDARQHSSSNMVIMLIGNKSDLEARRDVKREEGEAFAREHGLVFMETSAKTAANVEEAFINTAKAIYEKIQEGVLDINNEANGIKLGPQHTPSGSTAGLGQNRSSSGGC 685
            +YSY+FKYIIIGD GVGKSCLL QFT+K+F      TIGVEFG R+I + G+++KLQIWDTAGQE FR++TRSYYRGAAGAL+VYDITRR T+NHL++WL DAR  ++ N VI+LIGNK+DLEA+RDV  EE + FA E+GL+F+E SAKT  NVE+AF+  AK IY+ IQ+G LD+N   +G++  P     G      Q +    GC
Sbjct:    7 NYSYIFKYIIIGDMGVGKSCLLHQFTEKKFMADCPHTIGVEFGTRIIEVSGQKIKLQIWDTAGQERFRAVTRSYYRGAAGALMVYDITRRSTYNHLSSWLTDARNLTNPNTVIILIGNKADLEAQRDVTYEEAKQFAEENGLLFLEASAKTGENVEDAFLEAAKKIYQNIQDGSLDLNAAESGVQHKPSAPQGGRLTSEPQPQREGCGC 215
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BLAST of Ras-related protein Rab-2A vs. UniProt/SwissProt
Match: sp|Q05975|RAB2_LYMST (Ras-related protein Rab-2 OS=Lymnaea stagnalis OX=6523 GN=RAB2 PE=2 SV=1)

HSP 1 Score: 386.726 bits (992), Expect = 3.199e-135
Identity = 180/197 (91.37%), Postives = 193/197 (97.97%), Query Frame = 2 
Query:   56 MSYSYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQVKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRETFNHLTTWLEDARQHSSSNMVIMLIGNKSDLEARRDVKREEGEAFAREHGLVFMETSAKTAANVEEAFINTAKAIYEKIQEGVLDINNEANGIKLGPQHTPSGST 646
            MSY+YLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQ+KLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRR+TFNHLTTWLEDARQHS+SNMVIMLIGNKSDLEARR+VK+EEGEAFAREHGL+FMETSAKTAANVEEAFINTAK IY+KIQ+GV DINNEANGIK+GPQH+P+  +
Sbjct:    1 MSYAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRDTFNHLTTWLEDARQHSNSNMVIMLIGNKSDLEARREVKKEEGEAFAREHGLIFMETSAKTAANVEEAFINTAKEIYQKIQDGVFDINNEANGIKIGPQHSPASQS 197
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BLAST of Ras-related protein Rab-2A vs. UniProt/SwissProt
Match: sp|Q90965|RAB2A_CHICK (Ras-related protein Rab-2A OS=Gallus gallus OX=9031 GN=RAB2A PE=2 SV=1)

HSP 1 Score: 384.03 bits (985), Expect = 3.631e-134
Identity = 179/197 (90.86%), Postives = 192/197 (97.46%), Query Frame = 2 
Query:   56 MSYSYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQVKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRETFNHLTTWLEDARQHSSSNMVIMLIGNKSDLEARRDVKREEGEAFAREHGLVFMETSAKTAANVEEAFINTAKAIYEKIQEGVLDINNEANGIKLGPQHTPSGST 646
            M+Y+YLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQ+KLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRR+TFNHLTTWLEDARQHS+SNMVIMLIGNKSDLE+RR+VK+EEGEAFAREHGL+FMETSAKTA+NVEEAFINTAK IYEKIQEGV DINNEANGIK+GPQH  + +T
Sbjct:    1 MAYAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRDTFNHLTTWLEDARQHSNSNMVIMLIGNKSDLESRREVKKEEGEAFAREHGLIFMETSAKTASNVEEAFINTAKEIYEKIQEGVFDINNEANGIKIGPQHAATNAT 197
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BLAST of Ras-related protein Rab-2A vs. UniProt/SwissProt
Match: sp|P53994|RAB2A_MOUSE (Ras-related protein Rab-2A OS=Mus musculus OX=10090 GN=Rab2a PE=1 SV=1)

HSP 1 Score: 384.03 bits (985), Expect = 3.836e-134
Identity = 179/199 (89.95%), Postives = 193/199 (96.98%), Query Frame = 2 
Query:   56 MSYSYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQVKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRETFNHLTTWLEDARQHSSSNMVIMLIGNKSDLEARRDVKREEGEAFAREHGLVFMETSAKTAANVEEAFINTAKAIYEKIQEGVLDINNEANGIKLGPQHTPSGSTAG 652
            M+Y+YLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQ+KLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRR+TFNHLTTWLEDARQHS+SNMVIMLIGNKSDLE+RR+VK+EEGEAFAREHGL+FMETSAKTA+NVEEAFINTAK IYEKIQEGV DINNEANGIK+GPQH  + ++ G
Sbjct:    1 MAYAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRDTFNHLTTWLEDARQHSNSNMVIMLIGNKSDLESRREVKKEEGEAFAREHGLIFMETSAKTASNVEEAFINTAKEIYEKIQEGVFDINNEANGIKIGPQHAATNASHG 199
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BLAST of Ras-related protein Rab-2A vs. UniProt/SwissProt
Match: sp|Q5R6B6|RAB2A_PONAB (Ras-related protein Rab-2A OS=Pongo abelii OX=9601 GN=RAB2A PE=2 SV=1)

HSP 1 Score: 383.645 bits (984), Expect = 5.444e-134
Identity = 179/197 (90.86%), Postives = 192/197 (97.46%), Query Frame = 2 
Query:   56 MSYSYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQVKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRETFNHLTTWLEDARQHSSSNMVIMLIGNKSDLEARRDVKREEGEAFAREHGLVFMETSAKTAANVEEAFINTAKAIYEKIQEGVLDINNEANGIKLGPQHTPSGST 646
            M+Y+YLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQ+KLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRR+TFNHLTTWLEDARQHS+SNMVIMLIGNKSDLE+RR+VK+EEGEAFAREHGL+FMETSAKTA+NVEEAFINTAK IYEKIQEGV DINNEANGIK+GPQH  + +T
Sbjct:    1 MAYAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRDTFNHLTTWLEDARQHSNSNMVIMLIGNKSDLESRREVKKEEGEAFAREHGLIFMETSAKTASNVEEAFINTAKEIYEKIQEGVFDINNEANGIKIGPQHAATNAT 197
[Close]
BLAST of Ras-related protein Rab-2A vs. UniProt/SwissProt
Match: sp|Q4R4X6|RAB2A_MACFA (Ras-related protein Rab-2A OS=Macaca fascicularis OX=9541 GN=RAB2A PE=2 SV=1)

HSP 1 Score: 383.645 bits (984), Expect = 5.444e-134
Identity = 179/197 (90.86%), Postives = 192/197 (97.46%), Query Frame = 2 
Query:   56 MSYSYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQVKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRETFNHLTTWLEDARQHSSSNMVIMLIGNKSDLEARRDVKREEGEAFAREHGLVFMETSAKTAANVEEAFINTAKAIYEKIQEGVLDINNEANGIKLGPQHTPSGST 646
            M+Y+YLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQ+KLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRR+TFNHLTTWLEDARQHS+SNMVIMLIGNKSDLE+RR+VK+EEGEAFAREHGL+FMETSAKTA+NVEEAFINTAK IYEKIQEGV DINNEANGIK+GPQH  + +T
Sbjct:    1 MAYAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRDTFNHLTTWLEDARQHSNSNMVIMLIGNKSDLESRREVKKEEGEAFAREHGLIFMETSAKTASNVEEAFINTAKEIYEKIQEGVFDINNEANGIKIGPQHAATNAT 197
[Close]
BLAST of Ras-related protein Rab-2A vs. TrEMBL
Match: A0A1S3JC63 (ras-related protein Rab-2 isoform X3 OS=Lingula unguis OX=7574 GN=LOC106171596 PE=4 SV=1)

HSP 1 Score: 406.371 bits (1043), Expect = 1.422e-140
Identity = 194/212 (91.51%), Postives = 201/212 (94.81%), Query Frame = 2 
Query:   56 MSYSYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQVKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRETFNHLTTWLEDARQHSSSNMVIMLIGNKSDLEARRDVKREEGEAFAREHGLVFMETSAKTAANVEEAFINTAKAIYEKIQEGVLDINNEANGIKLGPQHTPSG-STAGLGQNRSSSGGCC 688
            MSY+YLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQ+KLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRR+TFNHLTTWLEDARQHSSSNMVIMLIGNKSDLEARRDVK+EEGEAFAREHGL+FMETSAKTAANVEEAFINTAKAIYEK+QEGVLDINNEANGIKLGPQH+PS  S A  G      GGCC
Sbjct:    1 MSYAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRDTFNHLTTWLEDARQHSSSNMVIMLIGNKSDLEARRDVKKEEGEAFAREHGLIFMETSAKTAANVEEAFINTAKAIYEKVQEGVLDINNEANGIKLGPQHSPSNPSMAAGGATGKQDGGCC 212
[Close]
BLAST of Ras-related protein Rab-2A vs. TrEMBL
Match: A0A2B4SQJ0 (Ras-related protein Rab-2 OS=Stylophora pistillata OX=50429 GN=RAB2 PE=4 SV=1)

HSP 1 Score: 404.831 bits (1039), Expect = 7.185e-140
Identity = 192/212 (90.57%), Postives = 202/212 (95.28%), Query Frame = 2 
Query:   56 MSYSYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQVKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRETFNHLTTWLEDARQHSSSNMVIMLIGNKSDLEARRDVKREEGEAFAREHGLVFMETSAKTAANVEEAFINTAKAIYEKIQEGVLDINNEANGIKLGPQHTPSGSTAGLGQNRS-SSGGCC 688
            MSY+YLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQ+KLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRR+TFNHLTTWLEDARQHSSSNMVIMLIGNKSDLEARRDV++EEGEAFAREHGL+FMETSAKTAANVEEAFINTAK IY+KIQEGV DINNEANGIK+GPQH+PS  +  LG  RS  SGGCC
Sbjct:    1 MSYAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRDTFNHLTTWLEDARQHSSSNMVIMLIGNKSDLEARRDVRKEEGEAFAREHGLIFMETSAKTAANVEEAFINTAKEIYQKIQEGVFDINNEANGIKIGPQHSPSNPSVPLGGGRSQDSGGCC 212
[Close]
BLAST of Ras-related protein Rab-2A vs. TrEMBL
Match: H2YDW1 (Uncharacterized protein OS=Ciona savignyi OX=51511 PE=4 SV=1)

HSP 1 Score: 401.749 bits (1031), Expect = 9.440e-139
Identity = 192/213 (90.14%), Postives = 202/213 (94.84%), Query Frame = 2 
Query:   56 MSYSYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQVKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRETFNHLTTWLEDARQHSSSNMVIMLIGNKSDLEARRDVKREEGEAFAREHGLVFMETSAKTAANVEEAFINTAKAIYEKIQEGVLDINNEANGIKLGPQHTPSGSTAGLGQNRSSS--GGCC 688
            MSY+YLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDG+Q+KLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRR+TFNHLTTWLEDARQHSSSNMVIMLIGNKSDLEARR+VK+EEGEAFAREHGL+FMETSAKTAANVEEAFINTAK IYEKIQEGV DINNEANGIKLGPQH+P+   AG  + R SS  GGCC
Sbjct:    1 MSYAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGRQIKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRDTFNHLTTWLEDARQHSSSNMVIMLIGNKSDLEARREVKKEEGEAFAREHGLIFMETSAKTAANVEEAFINTAKEIYEKIQEGVFDINNEANGIKLGPQHSPASGGAGGNRPRQSSDGGGCC 213
[Close]
BLAST of Ras-related protein Rab-2A vs. TrEMBL
Match: A0A1B6CLR0 (Uncharacterized protein OS=Clastoptera arizonana OX=38151 GN=g.16737 PE=4 SV=1)

HSP 1 Score: 399.053 bits (1024), Expect = 1.129e-137
Identity = 189/212 (89.15%), Postives = 200/212 (94.34%), Query Frame = 2 
Query:   56 MSYSYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQVKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRETFNHLTTWLEDARQHSSSNMVIMLIGNKSDLEARRDVKREEGEAFAREHGLVFMETSAKTAANVEEAFINTAKAIYEKIQEGVLDINNEANGIKLGPQHTPSGSTAGLG-QNRSSSGGCC 688
            MSY+YLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQ+KLQIWDTAGQE+FRSITRSYYRGAAGALLVYDITRRETFNHLTTWLEDARQHS+SNMVIMLIGNKSDLE+RR+VK+EEGEAFAREHGL+FMETSAKTAANVEEAFINTAK IYEKIQEGV DINNEANGIK+GPQH+PS  +   G Q    SGGCC
Sbjct:    1 MSYAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIWDTAGQEAFRSITRSYYRGAAGALLVYDITRRETFNHLTTWLEDARQHSNSNMVIMLIGNKSDLESRREVKKEEGEAFAREHGLIFMETSAKTAANVEEAFINTAKEIYEKIQEGVFDINNEANGIKIGPQHSPSNPSLPPGSQGSMQSGGCC 212
[Close]
BLAST of Ras-related protein Rab-2A vs. TrEMBL
Match: S4RNP2 (Uncharacterized protein OS=Petromyzon marinus OX=7757 PE=4 SV=1)

HSP 1 Score: 397.127 bits (1019), Expect = 6.160e-137
Identity = 190/212 (89.62%), Postives = 197/212 (92.92%), Query Frame = 2 
Query:   56 MSYSYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQVKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRETFNHLTTWLEDARQHSSSNMVIMLIGNKSDLEARRDVKREEGEAFAREHGLVFMETSAKTAANVEEAFINTAKAIYEKIQEGVLDINNEANGIKLGPQHTPSGSTAGLGQNR-SSSGGCC 688
            MSY+YLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQVKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRR+TFNHLTTWLEDARQHS+SNMVIMLIGNKSDLE+RR+VKREEGEAFAREHGLVFMETSAKTA+NVEEAFINTAK IYEKIQEGV DINNEANGIK+GPQH  S       QNR    GGCC
Sbjct:    1 MSYAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQVKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRDTFNHLTTWLEDARQHSNSNMVIMLIGNKSDLESRREVKREEGEAFAREHGLVFMETSAKTASNVEEAFINTAKEIYEKIQEGVFDINNEANGIKIGPQHAASSPGMASSQNRQQQDGGCC 212
[Close]
BLAST of Ras-related protein Rab-2A vs. Ensembl Cavefish
Match: rab2a (RAB2A, member RAS oncogene family [Source:NCBI gene;Acc:103041250])

HSP 1 Score: 383.645 bits (984), Expect = 5.186e-135
Identity = 179/197 (90.86%), Postives = 192/197 (97.46%), Query Frame = 2 
Query:   56 MSYSYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQVKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRETFNHLTTWLEDARQHSSSNMVIMLIGNKSDLEARRDVKREEGEAFAREHGLVFMETSAKTAANVEEAFINTAKAIYEKIQEGVLDINNEANGIKLGPQHTPSGST 646
            M+Y+YLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQ+KLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRR+TFNHLTTWLEDARQHS+SNMVIMLIGNKSDLE+RR+VK+EEGEAFAREHGL+FMETSAKTA+NVEEAFINTAK IYEKIQEGV DINNEANGIK+GPQH  + S+
Sbjct:    1 MAYAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRDTFNHLTTWLEDARQHSNSNMVIMLIGNKSDLESRREVKKEEGEAFAREHGLIFMETSAKTASNVEEAFINTAKEIYEKIQEGVFDINNEANGIKIGPQHAATNSS 197
[Close]
BLAST of Ras-related protein Rab-2A vs. Ensembl Cavefish
Match: rab14 (ras-related protein Rab-14 [Source:NCBI gene;Acc:103026976])

HSP 1 Score: 264.233 bits (674), Expect = 7.030e-88
Identity = 124/198 (62.63%), Postives = 155/198 (78.28%), Query Frame = 2 
Query:   59 SYSYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQVKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRETFNHLTTWLEDARQHSSSNMVIMLIGNKSDLEARRDVKREEGEAFAREHGLVFMETSAKTAANVEEAFINTAKAIYEKIQEGVLDINNEANGIKLGPQHTPSGSTAG 652
            +YSY+FKYIIIGD GVGKSCLL QFT+K+F      TIGVEFG R+I + G++VKLQIWDTAGQE FR++TRSYYRGAAGAL+VYDITRR T+NHL++WL DAR  ++ N VI+LIGNK+DLEA+RDV  EE + FA E+GL+F+E SAKT  NVE+AF+  AK IY+ IQ+G LD+N   +G+    QH P+    G
Sbjct:    7 NYSYIFKYIIIGDMGVGKSCLLHQFTEKKFMADCPHTIGVEFGTRIIEVSGQKVKLQIWDTAGQERFRAVTRSYYRGAAGALMVYDITRRSTYNHLSSWLTDARNLTNPNTVIILIGNKADLEAQRDVTYEEAKQFAEENGLLFLEASAKTGENVEDAFLEAAKKIYQNIQDGSLDLNAAESGV----QHKPTAPQGG 200
[Close]
BLAST of Ras-related protein Rab-2A vs. Ensembl Cavefish
Match: ENSAMXT00000039673.1 (pep primary_assembly:Astyanax_mexicanus-2.0:APWO02000139.1:3081649:3095559:1 gene:ENSAMXG00000040126.1 transcript:ENSAMXT00000039673.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 266.159 bits (679), Expect = 8.187e-88
Identity = 124/198 (62.63%), Postives = 156/198 (78.79%), Query Frame = 2 
Query:   59 SYSYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQVKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRETFNHLTTWLEDARQHSSSNMVIMLIGNKSDLEARRDVKREEGEAFAREHGLVFMETSAKTAANVEEAFINTAKAIYEKIQEGVLDINNEANGIKLGPQHTPSGSTAG 652
            +YSY+FKYIIIGD GVGKSCLL QFT+K+F      TIGVEFG R+I ++G+++KLQIWDTAGQE FR++TRSYYRGAAGAL+VYDITRR T+NHL++WL DAR  ++ N VI+LIGNK+DLEA+RDV  EE + FA E+GL+F+E SAKT  NVE+AF+  AK IY+ IQ+G LD+N   +G+    QH PS    G
Sbjct:   64 NYSYIFKYIIIGDMGVGKSCLLHQFTEKKFMADCPHTIGVEFGTRIIEVNGQKIKLQIWDTAGQERFRAVTRSYYRGAAGALMVYDITRRSTYNHLSSWLTDARNLTNPNTVIILIGNKADLEAQRDVTYEEAKQFAEENGLLFLEASAKTGENVEDAFLEAAKKIYQNIQDGSLDLNAAESGV----QHKPSAPQGG 257
[Close]
BLAST of Ras-related protein Rab-2A vs. Ensembl Cavefish
Match: rab4b (ras-related protein Rab-4B [Source:NCBI gene;Acc:103022831])

HSP 1 Score: 229.18 bits (583), Expect = 4.025e-74
Identity = 113/202 (55.94%), Postives = 143/202 (70.79%), Query Frame = 2 
Query:   59 SYSYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQVKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRETFNHLTTWLEDARQHSSSNMVIMLIGNKSDLEARRDVKREEGEAFAREHGLVFMETSAKTAANVEEAFINTAKAIYEKIQEGVLDINNEANGIKLGPQ-----HTPSGSTA 649
            +Y +LFK+++IG  G GKSCLL QF + +F+   + TIGVEFG+R++ + GK VKLQIWDTAGQE FRS+TRSYYRGAAGALLVYDIT RET+N LT WL DAR  +S N+VI+L GNK DL+A R+V   E   FA+E+ L+F+ETSA T  NVEEAF+  A+ I  KI+ G LD     +GI+ G         P G+ A
Sbjct:    4 TYDFLFKFLVIGSAGTGKSCLLHQFIENKFKQDSNHTIGVEFGSRVVNVGGKTVKLQIWDTAGQERFRSVTRSYYRGAAGALLVYDITSRETYNALTNWLTDARTLASPNIVIILCGNKKDLDADREVTFLEASRFAQENELMFLETSALTGENVEEAFLKCARTILNKIESGELDPERMGSGIQYGDASLRQLRQPRGTAA 205
[Close]
BLAST of Ras-related protein Rab-2A vs. Ensembl Cavefish
Match: rab4a (RAB4A, member RAS oncogene family [Source:NCBI gene;Acc:103032660])

HSP 1 Score: 226.868 bits (577), Expect = 2.517e-73
Identity = 110/187 (58.82%), Postives = 140/187 (74.87%), Query Frame = 2 
Query:   59 SYSYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQVKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRETFNHLTTWLEDARQHSSSNMVIMLIGNKSDLEARRDVKREEGEAFAREHGLVFMETSAKTAANVEEAFINTAKAIYEKIQEGVLDINNEANGIKLG 619
            +Y +LFK+++IG+ G GKSCLL QF +K+F+   + TIGVEFG+++I +  K VKLQIWDTAGQE FRS+TRSYYRGAAGALLVYDIT RET+N LT WL DAR  +S N+VI+L GNK DL+A R+V   E   FA+E+ L+F+ETSA T  NVEEAF+  A+ I  KI+ G LD     +GI+ G
Sbjct:    4 TYDFLFKFLVIGNAGTGKSCLLHQFIEKKFKDDSNHTIGVEFGSKIINVVNKFVKLQIWDTAGQERFRSVTRSYYRGAAGALLVYDITSRETYNALTNWLTDARMLASQNIVIILCGNKKDLDADREVTFLEASRFAQENELMFLETSALTGENVEEAFVQCARKILNKIESGELDPERMGSGIQYG 190
[Close]
BLAST of Ras-related protein Rab-2A vs. Ensembl Sea Lamprey
Match: rab2a (RAB2A, member RAS oncogene family [Source:ZFIN;Acc:ZDB-GENE-011212-2])

HSP 1 Score: 397.127 bits (1019), Expect = 4.733e-141
Identity = 190/212 (89.62%), Postives = 197/212 (92.92%), Query Frame = 2 
Query:   56 MSYSYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQVKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRETFNHLTTWLEDARQHSSSNMVIMLIGNKSDLEARRDVKREEGEAFAREHGLVFMETSAKTAANVEEAFINTAKAIYEKIQEGVLDINNEANGIKLGPQHTPSGSTAGLGQNR-SSSGGCC 688
            MSY+YLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQVKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRR+TFNHLTTWLEDARQHS+SNMVIMLIGNKSDLE+RR+VKREEGEAFAREHGLVFMETSAKTA+NVEEAFINTAK IYEKIQEGV DINNEANGIK+GPQH  S       QNR    GGCC
Sbjct:    1 MSYAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQVKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRDTFNHLTTWLEDARQHSNSNMVIMLIGNKSDLESRREVKREEGEAFAREHGLVFMETSAKTASNVEEAFINTAKEIYEKIQEGVFDINNEANGIKIGPQHAASSPGMASSQNRQQQDGGCC 212
[Close]
BLAST of Ras-related protein Rab-2A vs. Ensembl Sea Lamprey
Match: RAB2B (RAB2B, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:20246])

HSP 1 Score: 381.719 bits (979), Expect = 8.578e-135
Identity = 184/214 (85.98%), Postives = 196/214 (91.59%), Query Frame = 2 
Query:   56 MSYSYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQVKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRETFNHLTTWLEDARQHSSSNMVIMLIGNKSDLEARRDVKREEGEAFAREHGLVFMETSAKTAANVEEAFINTAKAIYEKIQEGVLDINNEANGIKLGPQHTPSGSTAGLGQNRSSSG---GCC 688
            MSY+YLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMI I GKQVKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRR+TFNHLT WLEDARQHS+SNMVIMLIGNKSDLE+RR+VK EEGEAFAREHGLVFMETSAKTAANVEEAFINTA+ IYEKIQEGV D+NNEANGIK+GPQ   +  +AG G+   S+G   GCC
Sbjct:    6 MSYAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMIAIGGKQVKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRDTFNHLTAWLEDARQHSNSNMVIMLIGNKSDLESRREVKCEEGEAFAREHGLVFMETSAKTAANVEEAFINTAREIYEKIQEGVFDVNNEANGIKIGPQQLGATPSAGQGRPAGSTGGSDGCC 219
[Close]
BLAST of Ras-related protein Rab-2A vs. Ensembl Sea Lamprey
Match: RAB2B (RAB2B, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:20246])

HSP 1 Score: 355.525 bits (911), Expect = 4.730e-125
Identity = 169/179 (94.41%), Postives = 175/179 (97.77%), Query Frame = 2 
Query:   56 MSYSYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQVKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRETFNHLTTWLEDARQHSSSNMVIMLIGNKSDLEARRDVKREEGEAFAREHGLVFMETSAKTAANVEEAFINTAKAIYEKIQEGVLDIN 592
            MSY+YLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMI IDGKQVKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRR+TFNHLTTWLEDARQHSSSNM+IMLIGNKSDLE+RRDVKREEGEAFAREHGLVFMETSAKTAANVEEAFINTAK IY++I EGV DIN
Sbjct:    6 MSYAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMINIDGKQVKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRDTFNHLTTWLEDARQHSSSNMIIMLIGNKSDLESRRDVKREEGEAFAREHGLVFMETSAKTAANVEEAFINTAKEIYQRIHEGVFDIN 184
[Close]
BLAST of Ras-related protein Rab-2A vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002219.1 (pep scaffold:Pmarinus_7.0:GL483980:50:9020:-1 gene:ENSPMAG00000002006.1 transcript:ENSPMAT00000002219.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 269.24 bits (687), Expect = 1.474e-90
Identity = 128/209 (61.24%), Postives = 157/209 (75.12%), Query Frame = 2 
Query:   59 SYSYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQVKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRETFNHLTTWLEDARQHSSSNMVIMLIGNKSDLEARRDVKREEGEAFAREHGLVFMETSAKTAANVEEAFINTAKAIYEKIQEGVLDINNEANGIKLGPQHTPSGSTAGLGQNRSSSGGC 685
            +YSY+FKYIIIGD GVGKSCLL QFT+K+F      TIGVEFG R+I + G++VKLQIWDTAGQE FR++TRSYYRGAAGAL+VYDITRR T+NHL++WL DAR  ++ N VI LIGNK+DLEA+RDV  EE + FA E+GL+F+E SAKT  NVEEAF+ TAK IY+ IQ+G LD+N   +G++  P     G  A   Q    S  C
Sbjct:    7 NYSYIFKYIIIGDMGVGKSCLLHQFTEKKFMADCPHTIGVEFGTRIIEVSGQKVKLQIWDTAGQERFRAVTRSYYRGAAGALMVYDITRRSTYNHLSSWLTDARNLTNPNTVIFLIGNKADLEAQRDVTYEEAKQFAEENGLLFLEASAKTGDNVEEAFLETAKKIYQNIQDGSLDLNAAESGVQHKPATPQPGRLASDAQPAKDSCSC 215
[Close]
BLAST of Ras-related protein Rab-2A vs. Ensembl Sea Lamprey
Match: rab4b (RAB4B, member RAS oncogene family [Source:NCBI gene;Acc:445498])

HSP 1 Score: 218.394 bits (555), Expect = 1.379e-70
Identity = 108/190 (56.84%), Postives = 136/190 (71.58%), Query Frame = 2 
Query:   56 MSYSYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQVKLQIWDTAGQESFRSITRSYYRGAAGALLVYDIT--RRETFNHLTTWLEDARQHSSSNMVIMLIGNKSDLEARRDVKREEGEAFAREHGLVFMETSAKTAANVEEAFINTAKAIYEKIQEGVLDINNEANGIKLG 619
            +S  +LFK+++IG  G GKSCLL QF + +F+   + TIGVEFG++++   GK VKLQIWDTAGQE FRS+TRSYYRGAAGALLVYDIT   RET+N LT WL DAR  +S N+ I+L GNK DLE  R+V   E   FA+E+ L+F+ETSA T  NVEEAF+  A+ I  KI+ G LD     +GI+ G
Sbjct:    7 VSTDFLFKFLVIGSAGTGKSCLLHQFIENKFKQDSNHTIGVEFGSKVVNTGGKTVKLQIWDTAGQERFRSVTRSYYRGAAGALLVYDITSGSRETYNALTNWLADARTLASPNIAIILCGNKKDLEPDREVTFLEASRFAQENELMFLETSALTGENVEEAFLKCARTILNKIESGELDPERMGSGIQYG 196
[Close]
BLAST of Ras-related protein Rab-2A vs. Ensembl Yeast
Match: YPT31 (Rab family GTPase; involved in the exocytic pathway; mediates intra-Golgi traffic or the budding of post-Golgi vesicles from the trans-Golgi; YPT31 has a paralog, YPT32, that arose from the whole genome duplication; localizes to the transitional and late Golgi [Source:SGD;Acc:S000000833])

HSP 1 Score: 189.504 bits (480), Expect = 1.850e-59
Identity = 98/215 (45.58%), Postives = 139/215 (64.65%), Query Frame = 2 
Query:   62 YSYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQVKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRETFNHLTTWLEDARQHSSSNMVIMLIGNKSDLEARRDVKREEGEAFAREHGLVFMETSAKTAANVEEAFINTAKAIYEKIQEGVLDI-NNEANGIKLGPQHTPSGSTAGL----GQNRSSSG-GCC 688
            Y  LFK ++IGD+GVGKS LL +FT   F      TIGVEF  R + IDGK++K QIWDTAGQE +R+IT +YYRGA GAL+VYDI++  ++ +   WL + R+++  N+ + LIGNKSDL   R V  EE + FA+E+ L+F ETSA  + NV++AF      IY+K+ +  +D+ ++ ANG   G    P+G T  L     +N+ ++G  CC
Sbjct:   10 YDLLFKIVLIGDSGVGKSNLLSRFTKNEFNMDSKSTIGVEFATRTLEIDGKRIKAQIWDTAGQERYRAITSAYYRGAVGALIVYDISKSSSYENCNHWLSELRENADDNVAVGLIGNKSDLAHLRAVPTEESKTFAQENQLLFTETSALNSENVDKAFEELINTIYQKVSKHQMDLGDSSANGNANGAS-APNGPTISLTPTPNENKKANGNNCC 223
[Close]
BLAST of Ras-related protein Rab-2A vs. Ensembl Yeast
Match: YPT1 (Rab family GTPase; involved in the ER-to-Golgi step of the secretory pathway; complex formation with the Rab escort protein Mrs6p is required for prenylation of Ypt1p by type II protein geranylgeranyltransferase (Bet2p-Bet4p); binds to unspliced HAC1 mRNA; regulates the unfolded protein response (UPR) by promoting the decay of HAC1 RNA; localizes to the early Golgi, the transitional Golgi and ER membranes, pre-autophagosomal structures, and cytoplasmic vesicles [Source:SGD;Acc:S000001856])

HSP 1 Score: 183.341 bits (464), Expect = 2.868e-57
Identity = 91/210 (43.33%), Postives = 141/210 (67.14%), Query Frame = 2 
Query:   62 YSYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQVKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRETFNHLTTWLEDARQHSSSNMVIMLIGNKSDLEARRDVKREEGEAFAREHGLVFMETSAKTAANVEEAFINTAKAIYEKIQEGVLDINNEANGIKLGPQHTPSGSTAGLGQNRSSS-GGCC 688
            Y YLFK ++IG++GVGKSCLLL+F+D  +   +  TIGV+F  + + +DGK VKLQIWDTAGQE FR+IT SYYRG+ G ++VYD+T +E+FN +  WL++  ++++S ++ +L+GNK DL+ +R V+ +  + FA  + + F+ETSA  + NVE+AF+  A+ I E + +  L   NE        +    G+    GQ+ +++ GGCC
Sbjct:    5 YDYLFKLLLIGNSGVGKSCLLLRFSDDTYTNDYISTIGVDFKIKTVELDGKTVKLQIWDTAGQERFRTITSSYYRGSHGIIIVYDVTDQESFNGVKMWLQEIDRYATSTVLKLLVGNKCDLKDKRVVEYDVAKEFADANKMPFLETSALDSTNVEDAFLTMARQIKESMSQQNL---NETT-----QKKEDKGNVNLKGQSLTNTGGGCC 206
[Close]
BLAST of Ras-related protein Rab-2A vs. Ensembl Yeast
Match: SEC4 (Rab family GTPase; essential for vesicle-mediated exocytic secretion and autophagy; associates with the exocyst component Sec15p and may regulate polarized delivery of transport vesicles to the exocyst at the plasma membrane [Source:SGD;Acc:S000001889])

HSP 1 Score: 183.341 bits (464), Expect = 4.085e-57
Identity = 85/175 (48.57%), Postives = 120/175 (68.57%), Query Frame = 2 
Query:   59 SYSYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQVKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRETFNHLTTWLEDARQHSSSNMVIMLIGNKSDLEARRDVKREEGEAFAREHGLVFMETSAKTAANVEEAFINTAKAIYEKIQEGVL 583
            SY  + K ++IGD+GVGKSCLL++F + +F P    TIG++F  + + I+GK+VKLQ+WDTAGQE FR+IT +YYRGA G +LVYD+T   TF ++  W +   +H++    ++L+GNKSD+E R  V  ++GEA A+E G+ F+E+SAK   NV E F   AK I EKI    L
Sbjct:   16 SYDSIMKILLIGDSGVGKSCLLVRFVEDKFNPSFITTIGIDFKIKTVDINGKKVKLQLWDTAGQERFRTITTAYYRGAMGIILVYDVTDERTFTNIKQWFKTVNEHANDEAQLLLVGNKSDMETRV-VTADQGEALAKELGIPFIESSAKNDDNVNEIFFTLAKLIQEKIDSNKL 189
[Close]
BLAST of Ras-related protein Rab-2A vs. Ensembl Yeast
Match: YPT32 (Rab family GTPase involved in the exocytic pathway; mediates intra-Golgi traffic or the budding of post-Golgi vesicles from the trans-Golgi; protein abundance increases in response to DNA replication stress; YPT32 has a paralog, YPT31, that arose from the whole genome duplication [Source:SGD;Acc:S000003178])

HSP 1 Score: 179.874 bits (455), Expect = 1.063e-55
Identity = 93/215 (43.26%), Postives = 133/215 (61.86%), Query Frame = 2 
Query:   62 YSYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQVKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRETFNHLTTWLEDARQHSSSNMVIMLIGNKSDLEARRDVKREEGEAFAREHGLVFMETSAKTAANVEEAFINTAKAIYEKIQEGVLDI------NNEANGIKLGPQHTPSGSTAGLGQNRSSSGGCC 688
            Y YLFK ++IGD+GVGKS LL +FT   F      TIGVEF  R I ++ K++K QIWDTAGQE +R+IT +YYRGA GAL+VYDI++  ++ +   WL + R+++  N+ + LIGNKSDL   R V  +E + FA E+ ++F ETSA  + NV++AF     AI++ + +  +D+      N  +NG   GP  T S + A     +  S  CC
Sbjct:   10 YDYLFKIVLIGDSGVGKSNLLSRFTTDEFNIESKSTIGVEFATRTIEVENKKIKAQIWDTAGQERYRAITSAYYRGAVGALIVYDISKSSSYENCNHWLTELRENADDNVAVGLIGNKSDLAHLRAVPTDEAKNFAMENQMLFTETSALNSDNVDKAFRELIVAIFQMVSKHQVDLSGSGTNNMGSNGAPKGP--TISLTPAPKEDKKKKSSNCC 222
[Close]
BLAST of Ras-related protein Rab-2A vs. Ensembl Yeast
Match: VPS21 (Endosomal Rab family GTPase; required for endocytic transport and sorting of vacuolar hydrolases; required for endosomal localization of the CORVET complex; required with YPT52 for MVB biogenesis and sorting; involved in autophagy and ionic stress tolerance; geranylgeranylation required for membrane association; protein abundance increases in response to DNA replication stress; mammalian Rab5 homolog; VPS21 has a paralog, YPT53, that arose from the whole genome duplication [Source:SGD;Acc:S000005615])

HSP 1 Score: 140.198 bits (352), Expect = 1.568e-40
Identity = 72/178 (40.45%), Postives = 105/178 (58.99%), Query Frame = 2 
Query:   74 FKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQVKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRETFNHLTTWLEDARQHSSSNMVIMLIGNKSDL---EARRDVKREEGEAFAREHGLVFMETSAKTAANVEEAFINTAKAIYEKIQEGVLDINNE 598
             K +++G+  VGKS ++L+F    F    + TIG  F  + +TI+   VK +IWDTAGQE F S+   YYR A  AL+VYD+T+ ++F     W+++  + +S +++I L+GNK D+      R V REEGE  A E GL+F ETSAKT  NV + F+   + I  K  E     +NE
Sbjct:    8 IKLVLLGEAAVGKSSIVLRFVSNDFAENKEPTIGAAFLTQRVTINEHTVKFEIWDTAGQERFASLAPMYYRNAQAALVVYDVTKPQSFIKARHWVKELHEQASKDIIIALVGNKIDMLQEGGERKVAREEGEKLAEEKGLLFFETSAKTGENVNDVFLGIGEKIPLKTAEEQNSASNE 185
[Close]
BLAST of Ras-related protein Rab-2A vs. Ensembl Nematostella
Match: EDO36687 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SHU3])

HSP 1 Score: 393.275 bits (1009), Expect = 3.444e-139
Identity = 185/197 (93.91%), Postives = 193/197 (97.97%), Query Frame = 2 
Query:   56 MSYSYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQVKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRETFNHLTTWLEDARQHSSSNMVIMLIGNKSDLEARRDVKREEGEAFAREHGLVFMETSAKTAANVEEAFINTAKAIYEKIQEGVLDINNEANGIKLGPQHTPSGST 646
            MSY+YLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQ+KLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRR+TFNHLTTWLEDARQHSSSNMVIMLIGNKSDLEARRDVK+EEGEAFAREHGL+FMETSAKTAANVEEAFINTAK IY+KIQEGV DINNEANGIKLGPQH+PS  +
Sbjct:    1 MSYAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRDTFNHLTTWLEDARQHSSSNMVIMLIGNKSDLEARRDVKKEEGEAFAREHGLIFMETSAKTAANVEEAFINTAKEIYQKIQEGVFDINNEANGIKLGPQHSPSNPS 197
[Close]
BLAST of Ras-related protein Rab-2A vs. Ensembl Nematostella
Match: EDO43319 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RZ04])

HSP 1 Score: 261.151 bits (666), Expect = 4.125e-87
Identity = 123/192 (64.06%), Postives = 152/192 (79.17%), Query Frame = 2 
Query:   59 SYSYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQVKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRETFNHLTTWLEDARQHSSSNMVIMLIGNKSDLEARRDVKREEGEAFAREHGLVFMETSAKTAANVEEAFINTAKAIYEKIQEGVLDINNEANGIKLGPQHTP 634
            +YSY+FKYIIIGD GVGKSCLL QFT+K+F      TIGVEFG R+I + G+++KLQIWDTAGQE FR++TRSYYRGAAGAL+VYDITRR T+NHL++WL DAR  ++ N VI LIGNKSDL+A+RDV  EE + FA E+GL+F E SAKT  NVE+AF+ TAK IY+ IQ+G LD+N   +G+    QH P
Sbjct:    8 NYSYIFKYIIIGDMGVGKSCLLHQFTEKKFMADCPHTIGVEFGTRIIEVSGQKIKLQIWDTAGQERFRAVTRSYYRGAAGALMVYDITRRSTYNHLSSWLTDARNLTNPNTVIFLIGNKSDLDAQRDVTYEEAKQFAEENGLLFCEASAKTGENVEDAFLETAKKIYQNIQDGSLDLNAAESGV----QHKP 195
[Close]
BLAST of Ras-related protein Rab-2A vs. Ensembl Nematostella
Match: EDO43047 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RZT6])

HSP 1 Score: 228.024 bits (580), Expect = 4.302e-74
Identity = 113/211 (53.55%), Postives = 148/211 (70.14%), Query Frame = 2 
Query:   59 SYSYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQVKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRETFNHLTTWLEDARQHSSSNMVIMLIGNKSDLEARRDVKREEGEAFAREHGLVFMETSAKTAANVEEAFINTAKAIYEKIQEGVLDINNEANGIKLG-PQHTPSGSTA-GLGQNRSSSGGC 685
            +Y +LFK+++IG  G GKSC+L QF + +F+     TIGVEFG++++ + GK VKLQIWDTAGQE FRS+TRSYYRGAAGALLVYDI+ RETFN LT WL DAR  +S N+VI+L+GNK DL+A R+V   E   FA+E+ L+F+ETSA T  NVEE F+  ++ I  KI+ G LD +   +GI+ G P    S     G G N++   GC
Sbjct:    4 TYDFLFKFLVIGSAGTGKSCILHQFIEGKFKQDSSHTIGVEFGSKIVNVGGKSVKLQIWDTAGQERFRSVTRSYYRGAAGALLVYDISSRETFNSLTNWLTDARTLASPNIVIILVGNKKDLDADREVTFLEASRFAQENELMFLETSALTGENVEEGFLKCSRTILNKIESGELDPDRMGSGIQYGDPSMRRSIRPGRGRGDNKNKCPGC 214
[Close]
BLAST of Ras-related protein Rab-2A vs. Ensembl Nematostella
Match: EDO47471 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RMA6])

HSP 1 Score: 198.749 bits (504), Expect = 7.092e-63
Identity = 95/198 (47.98%), Postives = 134/198 (67.68%), Query Frame = 2 
Query:   59 SYSYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQVKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRETFNHLTTWLEDARQHSSSNMVIMLIGNKSDLEARRDVKREEGEAFAREHGLVFMETSAKTAANVEEAFINTAKAIYEKIQEGVLDINNEANGIKLGPQHTPSGSTAG 652
            SY YLFK ++IGD+GVGK+C+L +F+D  F      TIG++F  + I + GK++KLQIWDTAGQE F +IT SYYRGA G +LVYDIT+ +TF++++ WL +  +H++ ++  M++GNK D++ RR V RE GE  AREHG+ F+ETSAKT  N+E+AF   A+ I +K  E   D    +N I +  Q    G   G
Sbjct:    5 SYDYLFKLLLIGDSGVGKTCILFRFSDDAFNTTFISTIGIDFKIKTIEMQGKKIKLQIWDTAGQERFHTITTSYYRGAMGIMLVYDITQEKTFDNISKWLRNIEEHANEDVEKMILGNKCDMDDRRIVSRERGEQIAREHGIRFLETSAKTNINIEQAFQYLAQDILKK--ELNKDSEEPSNNIHVHDQKDKKGGCCG 200
[Close]
BLAST of Ras-related protein Rab-2A vs. Ensembl Nematostella
Match: EDO41018 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S5I6])

HSP 1 Score: 193.356 bits (490), Expect = 1.083e-60
Identity = 88/183 (48.09%), Postives = 129/183 (70.49%), Query Frame = 2 
Query:   59 SYSYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQVKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRETFNHLTTWLEDARQHSSSNMVIMLIGNKSDLEARRDVKREEGEAFAREHGLVFMETSAKTAANVEEAFINTAKAIYEKIQEGVLDINNEANG 607
            +Y +LFK ++IGD+GVGK+C+L +F++  F      TIG++F  R I +DGK++KLQIWDTAGQE FR+IT +YYRGA G +LVYDIT  ++F ++  W+ +  +H+S ++  M++GNK D+E RR V +E GE  A E+G+ FMETSAK + NVEEAF   A+ I  K+ + + + N  + G
Sbjct:    4 TYDFLFKLLLIGDSGVGKTCVLFRFSEDAFNSTFISTIGIDFKIRTIELDGKKIKLQIWDTAGQERFRTITTAYYRGAMGIMLVYDITNDKSFENIKNWIRNIEEHASQDVEKMVLGNKCDMEDRRQVSKERGEQLAVEYGIKFMETSAKASINVEEAFFTLARDIKLKMDKKLENSNPASTG 186
[Close]
BLAST of Ras-related protein Rab-2A vs. Ensembl Medaka
Match: rab2a (RAB2A, member RAS oncogene family [Source:NCBI gene;Acc:101175108])

HSP 1 Score: 391.349 bits (1004), Expect = 5.641e-138
Identity = 185/212 (87.26%), Postives = 198/212 (93.40%), Query Frame = 2 
Query:   56 MSYSYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQVKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRETFNHLTTWLEDARQHSSSNMVIMLIGNKSDLEARRDVKREEGEAFAREHGLVFMETSAKTAANVEEAFINTAKAIYEKIQEGVLDINNEANGIKLGPQHTPSGSTAGLGQ-NRSSSGGCC 688
            M+Y+YLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQ+KLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRR+TFNHLTTWLEDARQHS+SNMVIMLIGNKSDLE+RR+VK+EEGEAFAREHGL+FMETSAKTA+NVEEAFINTAK IYEKIQEGV DINNEANGIK+GPQH  + ST    Q    + GGCC
Sbjct:    1 MAYAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRDTFNHLTTWLEDARQHSNSNMVIMLIGNKSDLESRREVKKEEGEAFAREHGLIFMETSAKTASNVEEAFINTAKEIYEKIQEGVFDINNEANGIKIGPQHPTTNSTLSSSQGGHQAGGGCC 212
[Close]
BLAST of Ras-related protein Rab-2A vs. Ensembl Medaka
Match: rab2a (RAB2A, member RAS oncogene family [Source:NCBI gene;Acc:101175108])

HSP 1 Score: 306.605 bits (784), Expect = 6.376e-105
Identity = 151/197 (76.65%), Postives = 162/197 (82.23%), Query Frame = 2 
Query:  101 GVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQVKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRETFNHLTTWLEDARQHSSSNMVIMLIGNKSDLEARRDVKREEGEAFAREHGLVFMETSAKTAANVEEAFINTAKAIYEKIQEGVLDINNEANGIKLGPQHTPSGSTAGLGQ-NRSSSGGCC 688
            GVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQ+KLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRR+TFNHLTTWLEDARQHS+SNMVIMLIGNKSDLE+RR+VK+EEGEAFAREHGL+FMETSAKTA+NVE                       EANGIK+GPQH  + ST    Q    + GGCC
Sbjct:   15 GVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRDTFNHLTTWLEDARQHSNSNMVIMLIGNKSDLESRREVKKEEGEAFAREHGLIFMETSAKTASNVE-----------------------EANGIKIGPQHPTTNSTLSSSQGGHQAGGGCC 188
[Close]
BLAST of Ras-related protein Rab-2A vs. Ensembl Medaka
Match: rab14 (ras-related protein Rab-14 [Source:NCBI gene;Acc:101162540])

HSP 1 Score: 264.233 bits (674), Expect = 7.540e-88
Identity = 124/209 (59.33%), Postives = 157/209 (75.12%), Query Frame = 2 
Query:   59 SYSYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQVKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRETFNHLTTWLEDARQHSSSNMVIMLIGNKSDLEARRDVKREEGEAFAREHGLVFMETSAKTAANVEEAFINTAKAIYEKIQEGVLDINNEANGIKLGPQHTPSGSTAGLGQNRSSSGGC 685
            +YSY+FKYIIIGD GVGKSCLL QFT+K+F      TIGVEFG R+I + G+++KLQIWDTAGQE FR++TRSYYRGAAGAL+VYDITRR T+NHL++WL DAR  ++ N VI+LIGNK+DLEA+RDV  EE + FA E+GL+F+E SAKT  NVE+AF+  AK IY+ IQ+G LD+N   +G++  P     G      Q +    GC
Sbjct:    7 NYSYIFKYIIIGDMGVGKSCLLHQFTEKKFMADCPHTIGVEFGTRIIEVSGQKIKLQIWDTAGQERFRAVTRSYYRGAAGALMVYDITRRSTYNHLSSWLTDARNLTNPNTVIILIGNKADLEAQRDVTYEEAKQFAEENGLLFLEASAKTGENVEDAFLEAAKKIYQNIQDGSLDLNAAESGVQHKPSAPQGGRLTSEPQPQREGCGC 215
[Close]
BLAST of Ras-related protein Rab-2A vs. Ensembl Medaka
Match: ENSORLT00000033612.1 (ras-related protein Rab-14 [Source:NCBI gene;Acc:101167092])

HSP 1 Score: 263.077 bits (671), Expect = 1.902e-87
Identity = 124/198 (62.63%), Postives = 155/198 (78.28%), Query Frame = 2 
Query:   59 SYSYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQVKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRETFNHLTTWLEDARQHSSSNMVIMLIGNKSDLEARRDVKREEGEAFAREHGLVFMETSAKTAANVEEAFINTAKAIYEKIQEGVLDINNEANGIKLGPQHTPSGSTAG 652
            +YS++FKYIIIGD GVGKSCLL QFT+K+F      TIGVEFG R++ + G++VKLQIWDTAGQE FR++TRSYYRGAAGAL+VYDITRR T+NHL++WL DAR  ++ N VI+LIGNK+DLEA+RDV  EE + FA E+GL+F+E SAKT  NVEEAF+  AK IY+ IQ+G LD+N   +G+    QH PS    G
Sbjct:    7 NYSFIFKYIIIGDMGVGKSCLLHQFTEKKFMADCPHTIGVEFGTRIMEVHGQKVKLQIWDTAGQERFRAVTRSYYRGAAGALMVYDITRRSTYNHLSSWLTDARNLTNPNTVIILIGNKADLEAQRDVTYEEAKQFADENGLLFLEASAKTGENVEEAFLEAAKRIYQNIQDGSLDLNAAESGV----QHKPSAPQGG 200
[Close]
BLAST of Ras-related protein Rab-2A vs. Ensembl Medaka
Match: rab14 (ras-related protein Rab-14 [Source:NCBI gene;Acc:101162540])

HSP 1 Score: 239.58 bits (610), Expect = 1.842e-78
Identity = 113/184 (61.41%), Postives = 142/184 (77.17%), Query Frame = 2 
Query:  101 GVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQVKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRETFNHLTTWLEDARQHSSSNMVIMLIGNKSDLEARRDVKREEGEAFAREHGLVFMETSAKTAANVEEAFINTAKAIYEKIQEGVLDINNEANGIKLGPQHTPSGSTAG 652
            GVGKSCLL QFT+K+F      TIGVEFG R+I + G+++KLQIWDTAGQE FR++TRSYYRGAAGAL+VYDITRR T+NHL++WL DAR  ++ N VI+LIGNK+DLEA+RDV  EE + FA E+GL+F+E SAKT  NVE+AF+  AK IY+ IQ+G LD+N   +G+    QH PS    G
Sbjct:    2 GVGKSCLLHQFTEKKFMADCPHTIGVEFGTRIIEVSGQKIKLQIWDTAGQERFRAVTRSYYRGAAGALMVYDITRRSTYNHLSSWLTDARNLTNPNTVIILIGNKADLEAQRDVTYEEAKQFAEENGLLFLEASAKTGENVEDAFLEAAKKIYQNIQDGSLDLNAAESGV----QHKPSAPQGG 181
[Close]
BLAST of Ras-related protein Rab-2A vs. Planmine SMEST
Match: SMESG000076159.1 (SMESG000076159.1)

HSP 1 Score: 440.654 bits (1132), Expect = 1.281e-157
Identity = 211/211 (100.00%), Postives = 211/211 (100.00%), Query Frame = 2 
Query:   56 MSYSYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQVKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRETFNHLTTWLEDARQHSSSNMVIMLIGNKSDLEARRDVKREEGEAFAREHGLVFMETSAKTAANVEEAFINTAKAIYEKIQEGVLDINNEANGIKLGPQHTPSGSTAGLGQNRSSSGGCC 688
            MSYSYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQVKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRETFNHLTTWLEDARQHSSSNMVIMLIGNKSDLEARRDVKREEGEAFAREHGLVFMETSAKTAANVEEAFINTAKAIYEKIQEGVLDINNEANGIKLGPQHTPSGSTAGLGQNRSSSGGCC
Sbjct:    1 MSYSYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQVKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRETFNHLTTWLEDARQHSSSNMVIMLIGNKSDLEARRDVKREEGEAFAREHGLVFMETSAKTAANVEEAFINTAKAIYEKIQEGVLDINNEANGIKLGPQHTPSGSTAGLGQNRSSSGGCC 211
[Close]
BLAST of Ras-related protein Rab-2A vs. Planmine SMEST
Match: SMESG000017457.1 (SMESG000017457.1)

HSP 1 Score: 379.407 bits (973), Expect = 1.956e-133
Identity = 183/189 (96.83%), Postives = 185/189 (97.88%), Query Frame = 2 
Query:   56 MSYSYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQVKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRETFNHLTTWLEDARQHSSSNMVIMLIGNKSDLEARRDVKREEGEAFAREHGLVFMETSAKTAANVEEAFINTAKAIYEKIQEGVLDINNEANGIKLGP 622
            MSYSYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQVKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRETF+HLTTWLEDARQHSSSNMVIMLIGNKSDLE RRDVKREEGE+FA EHGLVFMETSAKTA NVEEAFINTAKAIY KIQEGVLDINNEANGIKLGP
Sbjct:    1 MSYSYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQVKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRETFDHLTTWLEDARQHSSSNMVIMLIGNKSDLENRRDVKREEGESFAHEHGLVFMETSAKTALNVEEAFINTAKAIYGKIQEGVLDINNEANGIKLGP 189
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BLAST of Ras-related protein Rab-2A vs. Planmine SMEST
Match: SMESG000043454.1 (SMESG000043454.1)

HSP 1 Score: 292.738 bits (748), Expect = 2.832e-99
Identity = 135/189 (71.43%), Postives = 161/189 (85.19%), Query Frame = 2 
Query:   56 MSYSYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQVKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRETFNHLTTWLEDARQHSSSNMVIMLIGNKSDLEARRDVKREEGEAFAREHGLVFMETSAKTAANVEEAFINTAKAIYEKIQEGVLDINNEANGIKLGP 622
            MSY++LFK+IIIGDTGVGKSCLLLQFTDKRFQ  HD+TIGVEFG R ITID    KLQ+WDTAGQE+FRSITRSYYRG+A ALLVYDIT++ETF  + +WLEDARQ++SSN+V++LIGNKSDLE+ R V   EGEAF++EHGL+F+ETSAKT  NV+EAFI TA  IY+KIQ+G ++  NE  GIKLG 
Sbjct:    1 MSYAFLFKFIIIGDTGVGKSCLLLQFTDKRFQQTHDMTIGVEFGVRTITIDKSLTKLQVWDTAGQEAFRSITRSYYRGSAAALLVYDITKKETFTSVLSWLEDARQNASSNLVVILIGNKSDLESERQVSTYEGEAFSKEHGLLFLETSAKTCDNVDEAFIITANHIYQKIQDGTINCENETGGIKLGT 189
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BLAST of Ras-related protein Rab-2A vs. Planmine SMEST
Match: SMESG000044270.1 (SMESG000044270.1)

HSP 1 Score: 249.595 bits (636), Expect = 2.771e-82
Identity = 115/186 (61.83%), Postives = 150/186 (80.65%), Query Frame = 2 
Query:   59 SYSYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQVKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRETFNHLTTWLEDARQHSSSNMVIMLIGNKSDLEARRDVKREEGEAFAREHGLVFMETSAKTAANVEEAFINTAKAIYEKIQEGVLDINNEANGIKL 616
            +YSY+FKYIIIGD GVGKSCLL QFT+K+F      TIGVEFG R+I I+G+++KLQIWDTAGQE FR++TRSYYRGAAGALLVYD+TR+ TFNH+ +WL DAR  +S N VI +IGNKSD+  +RDV  +EG+A A E+GL+F+E SAKT   VE+AFI TA+ I++ IQ+G +D+N+  +G+ +
Sbjct:    7 NYSYIFKYIIIGDMGVGKSCLLHQFTEKKFMADCPHTIGVEFGTRIIEINGEKIKLQIWDTAGQERFRAVTRSYYRGAAGALLVYDVTRKSTFNHIHSWLTDARGLTSPNTVIFMIGNKSDMNEQRDVTYDEGKAVADENGLMFLECSAKTGEGVEDAFIETARKIFQNIQDGSVDLNSANDGVVM 192
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BLAST of Ras-related protein Rab-2A vs. Planmine SMEST
Match: SMESG000024495.1 (SMESG000024495.1)

HSP 1 Score: 246.514 bits (628), Expect = 3.714e-81
Identity = 116/205 (56.59%), Postives = 152/205 (74.15%), Query Frame = 2 
Query:   59 SYSYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQVKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRETFNHLTTWLEDARQHSSSNMVIMLIGNKSDLEARRDVKREEGEAFAREHGLVFMETSAKTAANVEEAFINTAKAIYEKIQEGVLDINNEANGIKLGPQHTPSGSTAGLGQNRSS 673
            +YSY+FKYIIIGD GVGKSCLL QFT+ +F P    TIGVEFG ++I + G++VKLQIWDTAGQE FR++TRSYYRGAAGA+LVYDITR+ TFN + +WL DAR  +S   V +LIGNK DL   R+V  E+G+  A E+G+ F+E SA+T  +VE+AFI TA+ IY+ IQEG +D+N+ +NG+ +    TP+ S     +N S 
Sbjct:    5 AYSYIFKYIIIGDMGVGKSCLLHQFTESKFLPDCPHTIGVEFGTKIIEVSGEKVKLQIWDTAGQERFRAVTRSYYRGAAGAILVYDITRKATFNRVHSWLSDARSLTSPQTVFILIGNKGDLNENREVSFEDGKELAEENGMFFLECSARTGEHVEDAFIETARKIYQHIQEGNVDLNSASNGVVMKRSPTPAKSAQSNQKNCSC 209
The following BLAST results are available for this feature:
BLAST of Ras-related protein Rab-2A vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
RAB2A1.134e-13490.86RAB2A, member RAS oncogene family [Source:HGNC Sym... [more]
RAB2B1.691e-13383.33RAB2B, member RAS oncogene family [Source:HGNC Sym... [more]
RAB2B3.558e-13386.89RAB2B, member RAS oncogene family [Source:HGNC Sym... [more]
RAB2A3.330e-10978.68RAB2A, member RAS oncogene family [Source:HGNC Sym... [more]
RAB141.407e-8759.33RAB14, member RAS oncogene family [Source:HGNC Sym... [more]
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BLAST of Ras-related protein Rab-2A vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
unc-1081.822e-13691.92pep chromosome:WBcel235:I:3824947:3826514:1 gene:W... [more]
unc-1082.484e-13691.92pep chromosome:WBcel235:I:3822883:3826514:1 gene:W... [more]
unc-1083.100e-9990.13pep chromosome:WBcel235:I:3825124:3826514:1 gene:W... [more]
rab-141.619e-8563.78RAB family [Source:UniProtKB/TrEMBL;Acc:Q93874][more]
rab-141.619e-8563.78RAB family [Source:UniProtKB/TrEMBL;Acc:Q93874][more]
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BLAST of Ras-related protein Rab-2A vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Rab23.256e-13585.92gene:FBgn0014009 transcript:FBtr0336658[more]
Rab23.256e-13585.92gene:FBgn0014009 transcript:FBtr0086124[more]
Rab149.882e-8562.69gene:FBgn0015791 transcript:FBtr0343678[more]
Rab149.882e-8562.69gene:FBgn0015791 transcript:FBtr0080626[more]
Rab141.947e-8460.98gene:FBgn0015791 transcript:FBtr0080627[more]
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BLAST of Ras-related protein Rab-2A vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
rab2a1.525e-13591.37RAB2A, member RAS oncogene family [Source:ZFIN;Acc... [more]
rab148.295e-8862.63RAB14, member RAS oncogene family [Source:ZFIN;Acc... [more]
rab14l2.518e-8762.12RAB14, member RAS oncogene family, like [Source:ZF... [more]
rab4b7.842e-7556.44RAB4B, member RAS oncogene family [Source:NCBI gen... [more]
rab4b7.842e-7556.44RAB4B, member RAS oncogene family [Source:NCBI gen... [more]
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BLAST of Ras-related protein Rab-2A vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
RAB2A1.454e-13491.33RAB2A, member RAS oncogene family [Source:NCBI gen... [more]
hus12.183e-13284.33HUS1 checkpoint clamp component [Source:Xenbase;Ac... [more]
RAB2A1.039e-11584.74RAB2A, member RAS oncogene family [Source:NCBI gen... [more]
map44.666e-7356.99microtubule associated protein 4 [Source:Xenbase;A... [more]
rab145.826e-7253.11RAB14, member RAS oncogene family [Source:NCBI gen... [more]
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BLAST of Ras-related protein Rab-2A vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Rab2a5.483e-13589.95RAB2A, member RAS oncogene family [Source:MGI Symb... [more]
Rab2b5.462e-13283.33RAB2B, member RAS oncogene family [Source:MGI Symb... [more]
Rab2b5.462e-13283.33RAB2B, member RAS oncogene family [Source:MGI Symb... [more]
Rab2b4.691e-11476.39RAB2B, member RAS oncogene family [Source:MGI Symb... [more]
Rab149.661e-8859.33RAB14, member RAS oncogene family [Source:MGI Symb... [more]
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BLAST of Ras-related protein Rab-2A vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q05975|RAB2_LYMST3.199e-13591.37Ras-related protein Rab-2 OS=Lymnaea stagnalis OX=... [more]
sp|Q90965|RAB2A_CHICK3.631e-13490.86Ras-related protein Rab-2A OS=Gallus gallus OX=903... [more]
sp|P53994|RAB2A_MOUSE3.836e-13489.95Ras-related protein Rab-2A OS=Mus musculus OX=1009... [more]
sp|Q5R6B6|RAB2A_PONAB5.444e-13490.86Ras-related protein Rab-2A OS=Pongo abelii OX=9601... [more]
sp|Q4R4X6|RAB2A_MACFA5.444e-13490.86Ras-related protein Rab-2A OS=Macaca fascicularis ... [more]
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BLAST of Ras-related protein Rab-2A vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A1S3JC631.422e-14091.51ras-related protein Rab-2 isoform X3 OS=Lingula un... [more]
A0A2B4SQJ07.185e-14090.57Ras-related protein Rab-2 OS=Stylophora pistillata... [more]
H2YDW19.440e-13990.14Uncharacterized protein OS=Ciona savignyi OX=51511... [more]
A0A1B6CLR01.129e-13789.15Uncharacterized protein OS=Clastoptera arizonana O... [more]
S4RNP26.160e-13789.62Uncharacterized protein OS=Petromyzon marinus OX=7... [more]
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BLAST of Ras-related protein Rab-2A vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
rab2a5.186e-13590.86RAB2A, member RAS oncogene family [Source:NCBI gen... [more]
rab147.030e-8862.63ras-related protein Rab-14 [Source:NCBI gene;Acc:1... [more]
ENSAMXT00000039673.18.187e-8862.63pep primary_assembly:Astyanax_mexicanus-2.0:APWO02... [more]
rab4b4.025e-7455.94ras-related protein Rab-4B [Source:NCBI gene;Acc:1... [more]
rab4a2.517e-7358.82RAB4A, member RAS oncogene family [Source:NCBI gen... [more]
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BLAST of Ras-related protein Rab-2A vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
rab2a4.733e-14189.62RAB2A, member RAS oncogene family [Source:ZFIN;Acc... [more]
RAB2B8.578e-13585.98RAB2B, member RAS oncogene family [Source:HGNC Sym... [more]
RAB2B4.730e-12594.41RAB2B, member RAS oncogene family [Source:HGNC Sym... [more]
ENSPMAT00000002219.11.474e-9061.24pep scaffold:Pmarinus_7.0:GL483980:50:9020:-1 gene... [more]
rab4b1.379e-7056.84RAB4B, member RAS oncogene family [Source:NCBI gen... [more]
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BLAST of Ras-related protein Rab-2A vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 5
Match NameE-valueIdentityDescription
YPT311.850e-5945.58Rab family GTPase; involved in the exocytic pathwa... [more]
YPT12.868e-5743.33Rab family GTPase; involved in the ER-to-Golgi ste... [more]
SEC44.085e-5748.57Rab family GTPase; essential for vesicle-mediated ... [more]
YPT321.063e-5543.26Rab family GTPase involved in the exocytic pathway... [more]
VPS211.568e-4040.45Endosomal Rab family GTPase; required for endocyti... [more]
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BLAST of Ras-related protein Rab-2A vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO366873.444e-13993.91Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO433194.125e-8764.06Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO430474.302e-7453.55Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO474717.092e-6347.98Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO410181.083e-6048.09Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Ras-related protein Rab-2A vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
rab2a5.641e-13887.26RAB2A, member RAS oncogene family [Source:NCBI gen... [more]
rab2a6.376e-10576.65RAB2A, member RAS oncogene family [Source:NCBI gen... [more]
rab147.540e-8859.33ras-related protein Rab-14 [Source:NCBI gene;Acc:1... [more]
ENSORLT00000033612.11.902e-8762.63ras-related protein Rab-14 [Source:NCBI gene;Acc:1... [more]
rab141.842e-7861.41ras-related protein Rab-14 [Source:NCBI gene;Acc:1... [more]
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BLAST of Ras-related protein Rab-2A vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000076159.11.281e-157100.00SMESG000076159.1[more]
SMESG000017457.11.956e-13396.83SMESG000017457.1[more]
SMESG000043454.12.832e-9971.43SMESG000043454.1[more]
SMESG000044270.12.771e-8261.83SMESG000044270.1[more]
SMESG000024495.13.714e-8156.59SMESG000024495.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30017717 ID=SMED30017717|Name=Ras-related protein Rab-2A|organism=Schmidtea mediterranea sexual|type=transcript|length=1052bp
AACTTTGTTACACATCTTCAACATTATAAAATTTAATAAACATACGTAGG
CCTAAATGTCATATTCTTACCTTTTTAAGTATATTATTATCGGAGATACT
GGTGTTGGAAAGTCATGTTTACTTTTACAGTTTACTGATAAAAGATTTCA
ACCAGTTCATGATTTAACCATCGGAGTGGAGTTTGGTGCTAGGATGATAA
CGATTGATGGAAAACAAGTTAAACTTCAAATTTGGGATACAGCTGGCCAG
GAATCATTCAGATCTATTACTAGGTCTTATTACAGAGGCGCTGCAGGTGC
TTTACTAGTTTATGACATAACAAGGCGAGAAACATTCAATCACCTCACAA
CCTGGCTTGAGGATGCACGACAACACTCCAGTTCAAATATGGTTATTATG
CTGATAGGTAATAAAAGTGATTTGGAAGCTCGAAGAGATGTAAAACGTGA
AGAAGGCGAAGCTTTTGCCCGAGAGCATGGCCTAGTGTTTATGGAAACAT
CAGCTAAGACTGCTGCAAACGTTGAAGAAGCATTTATTAACACAGCTAAA
GCGATTTATGAGAAAATCCAAGAAGGTGTTTTAGACATCAATAATGAAGC
CAATGGGATTAAACTCGGTCCACAACACACTCCTTCTGGATCAACGGCCG
GTTTAGGACAAAATAGGTCATCCAGTGGTGGATGTTGTTAATTACACTAC
TCCAATTATTATATTAAATCTCAATCAATCGTGACAAGCAAAGAACCTAG
AGTATATTTACTGTTTTATTTTAAAAAAAAATGTAGTGCGATATAACTCA
TTCCATTTGTAACAATTTTGCTGTTAAAAATTTATTCTTGAACAATGTCT
TATACCAGTGTCGGAAATAATATTTATTCCACTGAGGATATTGTTTTATA
GTGCAATACTTTTTGCCATTGACATTTCGCAGGTAAATATATATATATAT
AAATAATACAAGTTTGTATTCTGTATCTGATAAGAACTAACAATCAGAAT
ATCAAGTAGTGGGTTTGTGTGATATTTTACTGCATTATTGTTCTGGGTTC
AA
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protein sequence of SMED30017717-orf-1

>SMED30017717-orf-1 ID=SMED30017717-orf-1|Name=SMED30017717-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=212bp
MSYSYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITI
DGKQVKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRETFNHLTTW
LEDARQHSSSNMVIMLIGNKSDLEARRDVKREEGEAFAREHGLVFMETSA
KTAANVEEAFINTAKAIYEKIQEGVLDINNEANGIKLGPQHTPSGSTAGL
GQNRSSSGGCC*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: molecular function
TermDefinition
GO:0003924GTPase activity
GO:0019003GDP binding
GO:0005525GTP binding
GO:0000166nucleotide binding
Vocabulary: biological process
TermDefinition
GO:0007030Golgi organization
GO:0007264small GTPase mediated signal transduction
GO:0006810transport
GO:0015031protein transport
GO:0016192vesicle-mediated transport
Vocabulary: cellular component
TermDefinition
GO:0042470melanosome
GO:0000139Golgi membrane
GO:0005783endoplasmic reticulum
GO:0005789endoplasmic reticulum membrane
GO:0005794Golgi apparatus
GO:0016020membrane
GO:0033116endoplasmic reticulum-Golgi intermediate compartment membrane
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000020protonephridia
PLANA:0000026gut
PLANA:0002032epidermal cell
Vocabulary: INTERPRO
TermDefinition
IPR005225Small_GTP-bd_dom
IPR001806Small_GTPase
IPR027417P-loop_NTPase
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availablePRINTSPR00449RASTRNSFRMNGcoord: 48..70
score: 55.39
coord: 7..28
score: 51.86
coord: 145..167
score: 46.63
coord: 110..123
score: 50.42
coord: 30..46
score: 32.76
NoneNo IPR availableSMARTSM00175rab_sub_5coord: 7..170
e-value: 1.1E-108
score: 377.1
NoneNo IPR availableSMARTSM00173ras_sub_4coord: 4..170
e-value: 5.6E-37
score: 138.8
NoneNo IPR availableSMARTSM00174rho_sub_3coord: 9..170
e-value: 1.1E-11
score: 30.2
NoneNo IPR availableSMARTSM00176ran_sub_2coord: 12..200
e-value: 7.2E-6
score: 33.8
NoneNo IPR availableGENE3DG3DSA:3.40.50.300coord: 1..199
e-value: 9.4E-69
score: 232.8
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 192..211
NoneNo IPR availablePANTHERPTHR24073FAMILY NOT NAMEDcoord: 3..198
NoneNo IPR availablePANTHERPTHR24073:SF990RAS-RELATED PROTEIN RAB-2Acoord: 3..198
NoneNo IPR availablePROSITEPS51419RABcoord: 2..211
score: 36.317
NoneNo IPR availableCDDcd01866Rab2coord: 3..170
e-value: 8.72482E-132
score: 365.207
IPR001806Small GTPasePFAMPF00071Rascoord: 8..168
e-value: 3.0E-62
score: 209.0
IPR005225Small GTP-binding protein domainTIGRFAMTIGR00231TIGR00231coord: 7..161
e-value: 7.7E-33
score: 111.5
IPR027417P-loop containing nucleoside triphosphate hydrolaseSUPERFAMILYSSF52540P-loop containing nucleoside triphosphate hydrolasescoord: 1..181