DNA polymerase kappa

Overview


Name	DNA polymerase kappa
Smed ID	SMED30017662
Length (bp)	1964

Neoblast Clusters

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of DNA polymerase kappa (SMED30017662) t-SNE clustered cells

Violin plots show distribution of expression levels for DNA polymerase kappa (SMED30017662) in cells (dots) of each of the 12 neoblast clusters.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30017662

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 1

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication	Specimen	Lifecycle	Evidence
X1 cell	SMED30017662	SMESG000069346.1	SmedASXL_019932	SmedAsxl_ww_GCZZ01	PMID:26114597 Zhu et al., 2015

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Homology

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BLAST of DNA polymerase kappa vs. Ensembl Human
Match: POLK (DNA polymerase kappa [Source:HGNC Symbol;Acc:HGNC:9183])

HSP 1 Score: 371.318 bits (952), Expect = 5.570e-117
Identity = 246/647 (38.02%), Postives = 360/647 (55.64%), Query Frame = 3

Query:   81 LSSLKVNDNKAGMENLDKKKINETILEASRGSKYYEHEVXXXXXXXXXXXXXXXXYNSLSENDILRGVKKANKLLENISINRNLNQTFVHIDMDAYFAAVEINDNPSLRTKPMAVGSSSMLSTSNYVARKFGVRAGMPGFIAKKLCPDIILIEPNFNKYISISRIFRKIFLDYDINYSACGLDEATLDITEHLKNRISY-SDKQRTF-SCNVSCECRIPIQINSKQTK--------LFK----------------ICDECGKLIGAQEKTFSISSWSAVEELRFRIFARTQLTSSAGMASNGLLAKIVSDINKPNGQYHLSSDPWDINVFIKQLPVGKVPGIGKVSERKLDVLGIVKCEDFYHKRGALYHLFKPCMFSYFMRISLGXXXXXXXXXXXXXXXNGIDRKSMSVERTFPDCNDPILLMEKCKTLCKDLWKELLKKNLLGKCISIKLKLSSFEVRTRAFSNLEATNDLNNITNCACELLQTEINNNQPHKLCLRLLGVRISVL--------------------SMKLSPLATLTQLNIKEAF---------------KNQEMK--AESTKKEEGVNHE--------EQLKEKCS-----SEVIKDDSIVQCPVCFVS---VNISNINTHLDFCI-SPANSE 1781
            L  + +NDNKAGME LDK+KIN+ I+EA++GS++Y +E+KK K+  +++  + ++   ++   + +   + ++    +  +RNL+ T VHIDMDA++AAVE+ DNP L+ KP+AVGS SMLSTSNY AR+FGVRA MPGFIAK+LCP +I++ PNF+KY ++S+  ++I  DYD N+ A  LDEA L+IT+HL+ R ++  DK+R F     S E   P +  +K ++        LF+                  ++    I      F  S+   V+E+RFRI  +T LT+SAG+A N +LAK+ SD NKPNGQY +  +   +  FIK LP+ KV GIGKV+E+ L  LGI+ C + Y +R  L  LF    + YF+ ISLG          +    +G +RKSMSVERTF + N        C+ LC +L ++L K+ L G+ ++IKLK  +FEV+TRA +     +    I   A ELL+TEI+ + PH L LRL+GVRIS                      +  LS      +   K+ F               K  E K   + T K E VN +        + LK+K +     SE   D  I+ CPVCF +   +++  +N H+D C+  P+ SE
Sbjct:   16 LLRMGLNDNKAGMEGLDKEKINKIIMEATKGSRFYGNELKKEKQVNQRIENMMQQKAQITSQQLRKAQLQVDRFAMELEQSRNLSNTIVHIDMDAFYAAVEMRDNPELKDKPIAVGSMSMLSTSNYHARRFGVRAAMPGFIAKRLCPQLIIVPPNFDKYRAVSKEVKEILADYDPNFMAMSLDEAYLNITKHLEERQNWPEDKRRYFIKMGSSVENDNPGKEVNKLSEHERSISPLLFEESPSDVQPPGDPFQVNFEEQNNPQILQNSVVFGTSAQEVVKEIRFRIEQKTTLTASAGIAPNTMLAKVCSDKNKPNGQYQILPNRQAVMDFIKDLPIRKVSGIGKVTEKMLKALGIITCTELYQQRALLSLLFSETSWHYFLHISLG-------LGSTHLTRDG-ERKSMSVERTFSEINKAEEQYSLCQELCSELAQDLQKERLKGRTVTIKLKNVNFEVKTRASTVSSVVSTAEEIFAIAKELLKTEIDADFPHPLRLRLMGVRISSFPNEEDRKHQQRSIIGFLQAGNQALSATECTLEKTDKDKFVKPLEMSHKKSFFDKKRSERKWSHQDTFKCEAVNKQSFQTSQPFQVLKKKMNENLEISENSDDCQILTCPVCFRAQGCISLEALNKHVDECLDGPSISE 654

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BLAST of DNA polymerase kappa vs. Ensembl Human
Match: POLK (DNA polymerase kappa [Source:HGNC Symbol;Acc:HGNC:9183])

HSP 1 Score: 322.398 bits (825), Expect = 7.997e-103
Identity = 186/444 (41.89%), Postives = 271/444 (61.04%), Query Frame = 3

Query:   81 LSSLKVNDNKAGMENLDKKKINETILEASRGSKYYEHEVXXXXXXXXXXXXXXXXYNSLSENDILRGVKKANKLLENISINRNLNQTFVHIDMDAYFAAVEINDNPSLRTKPMAVGSSSMLSTSNYVARKFGVRAGMPGFIAKKLCPDIILIEPNFNKYISISRIFRKIFLDYDINYSACGLDEATLDITEHLKNRISY-SDKQRTF-SCNVSCECRIPIQINSKQTK--------LFK----------------ICDECGKLIGAQEKTFSISSWSAVEELRFRIFARTQLTSSAGMASNGLLAKIVSDINKPNGQYHLSSDPWDINVFIKQLPVGKVPGIGKVSERKLDVLGIVKCEDFYHKRGALYHLFKPCMFSYFMRISLGXXXXXXXXXXXXXXXNGIDRKSMSVERTFPDCNDPILLMEKCKTLCKDLWKELLKKNL 1334
            L  + +NDNKAGME LDK+KIN+ I+EA++GS++Y +E+KK K+  +++  + ++   ++   + +   + ++    +  +RNL+ T VHIDMDA++AAVE+ DNP L+ KP+AVGS SMLSTSNY AR+FGVRA MPGFIAK+LCP +I++ PNF+KY ++S+  ++I  DYD N+ A  LDEA L+IT+HL+ R ++  DK+R F     S E   P +  +K ++        LF+                  ++    I      F  S+   V+E+RFRI  +T LT+SAG+A N +LAK+ SD NKPNGQY +  +   +  FIK LP+ KV GIGKV+E+ L  LGI+ C + Y +R  L  LF    + YF+ ISLG GS   +           +RKSMSVERTF + N        C+ LC +L ++L K+ L
Sbjct:   16 LLRMGLNDNKAGMEGLDKEKINKIIMEATKGSRFYGNELKKEKQVNQRIENMMQQKAQITSQQLRKAQLQVDRFAMELEQSRNLSNTIVHIDMDAFYAAVEMRDNPELKDKPIAVGSMSMLSTSNYHARRFGVRAAMPGFIAKRLCPQLIIVPPNFDKYRAVSKEVKEILADYDPNFMAMSLDEAYLNITKHLEERQNWPEDKRRYFIKMGSSVENDNPGKEVNKLSEHERSISPLLFEESPSDVQPPGDPFQVNFEEQNNPQILQNSVVFGTSAQEVVKEIRFRIEQKTTLTASAGIAPNTMLAKVCSDKNKPNGQYQILPNRQAVMDFIKDLPIRKVSGIGKVTEKMLKALGIITCTELYQQRALLSLLFSETSWHYFLHISLGLGSTHLTRDG--------ERKSMSVERTFSEINKAEEQYSLCQELCSELAQDLQKERL 451

[Close]

BLAST of DNA polymerase kappa vs. Ensembl Human
Match: POLK (DNA polymerase kappa [Source:HGNC Symbol;Acc:HGNC:9183])

HSP 1 Score: 322.013 bits (824), Expect = 1.672e-102
Identity = 186/444 (41.89%), Postives = 271/444 (61.04%), Query Frame = 3

Query:   81 LSSLKVNDNKAGMENLDKKKINETILEASRGSKYYEHEVXXXXXXXXXXXXXXXXYNSLSENDILRGVKKANKLLENISINRNLNQTFVHIDMDAYFAAVEINDNPSLRTKPMAVGSSSMLSTSNYVARKFGVRAGMPGFIAKKLCPDIILIEPNFNKYISISRIFRKIFLDYDINYSACGLDEATLDITEHLKNRISY-SDKQRTF-SCNVSCECRIPIQINSKQTK--------LFK----------------ICDECGKLIGAQEKTFSISSWSAVEELRFRIFARTQLTSSAGMASNGLLAKIVSDINKPNGQYHLSSDPWDINVFIKQLPVGKVPGIGKVSERKLDVLGIVKCEDFYHKRGALYHLFKPCMFSYFMRISLGXXXXXXXXXXXXXXXNGIDRKSMSVERTFPDCNDPILLMEKCKTLCKDLWKELLKKNL 1334
            L  + +NDNKAGME LDK+KIN+ I+EA++GS++Y +E+KK K+  +++  + ++   ++   + +   + ++    +  +RNL+ T VHIDMDA++AAVE+ DNP L+ KP+AVGS SMLSTSNY AR+FGVRA MPGFIAK+LCP +I++ PNF+KY ++S+  ++I  DYD N+ A  LDEA L+IT+HL+ R ++  DK+R F     S E   P +  +K ++        LF+                  ++    I      F  S+   V+E+RFRI  +T LT+SAG+A N +LAK+ SD NKPNGQY +  +   +  FIK LP+ KV GIGKV+E+ L  LGI+ C + Y +R  L  LF    + YF+ ISLG GS   +           +RKSMSVERTF + N        C+ LC +L ++L K+ L
Sbjct:   16 LLRMGLNDNKAGMEGLDKEKINKIIMEATKGSRFYGNELKKEKQVNQRIENMMQQKAQITSQQLRKAQLQVDRFAMELEQSRNLSNTIVHIDMDAFYAAVEMRDNPELKDKPIAVGSMSMLSTSNYHARRFGVRAAMPGFIAKRLCPQLIIVPPNFDKYRAVSKEVKEILADYDPNFMAMSLDEAYLNITKHLEERQNWPEDKRRYFIKMGSSVENDNPGKEVNKLSEHERSISPLLFEESPSDVQPPGDPFQVNFEEQNNPQILQNSVVFGTSAQEVVKEIRFRIEQKTTLTASAGIAPNTMLAKVCSDKNKPNGQYQILPNRQAVMDFIKDLPIRKVSGIGKVTEKMLKALGIITCTELYQQRALLSLLFSETSWHYFLHISLGLGSTHLTRDG--------ERKSMSVERTFSEINKAEEQYSLCQELCSELAQDLQKERL 451

[Close]

BLAST of DNA polymerase kappa vs. Ensembl Human
Match: POLK (DNA polymerase kappa [Source:HGNC Symbol;Acc:HGNC:9183])

HSP 1 Score: 321.627 bits (823), Expect = 3.186e-102
Identity = 186/444 (41.89%), Postives = 271/444 (61.04%), Query Frame = 3

Query:   81 LSSLKVNDNKAGMENLDKKKINETILEASRGSKYYEHEVXXXXXXXXXXXXXXXXYNSLSENDILRGVKKANKLLENISINRNLNQTFVHIDMDAYFAAVEINDNPSLRTKPMAVGSSSMLSTSNYVARKFGVRAGMPGFIAKKLCPDIILIEPNFNKYISISRIFRKIFLDYDINYSACGLDEATLDITEHLKNRISY-SDKQRTF-SCNVSCECRIPIQINSKQTK--------LFK----------------ICDECGKLIGAQEKTFSISSWSAVEELRFRIFARTQLTSSAGMASNGLLAKIVSDINKPNGQYHLSSDPWDINVFIKQLPVGKVPGIGKVSERKLDVLGIVKCEDFYHKRGALYHLFKPCMFSYFMRISLGXXXXXXXXXXXXXXXNGIDRKSMSVERTFPDCNDPILLMEKCKTLCKDLWKELLKKNL 1334
            L  + +NDNKAGME LDK+KIN+ I+EA++GS++Y +E+KK K+  +++  + ++   ++   + +   + ++    +  +RNL+ T VHIDMDA++AAVE+ DNP L+ KP+AVGS SMLSTSNY AR+FGVRA MPGFIAK+LCP +I++ PNF+KY ++S+  ++I  DYD N+ A  LDEA L+IT+HL+ R ++  DK+R F     S E   P +  +K ++        LF+                  ++    I      F  S+   V+E+RFRI  +T LT+SAG+A N +LAK+ SD NKPNGQY +  +   +  FIK LP+ KV GIGKV+E+ L  LGI+ C + Y +R  L  LF    + YF+ ISLG GS   +           +RKSMSVERTF + N        C+ LC +L ++L K+ L
Sbjct:   16 LLRMGLNDNKAGMEGLDKEKINKIIMEATKGSRFYGNELKKEKQVNQRIENMMQQKAQITSQQLRKAQLQVDRFAMELEQSRNLSNTIVHIDMDAFYAAVEMRDNPELKDKPIAVGSMSMLSTSNYHARRFGVRAAMPGFIAKRLCPQLIIVPPNFDKYRAVSKEVKEILADYDPNFMAMSLDEAYLNITKHLEERQNWPEDKRRYFIKMGSSVENDNPGKEVNKLSEHERSISPLLFEESPSDVQPPGDPFQVNFEEQNNPQILQNSVVFGTSAQEVVKEIRFRIEQKTTLTASAGIAPNTMLAKVCSDKNKPNGQYQILPNRQAVMDFIKDLPIRKVSGIGKVTEKMLKALGIITCTELYQQRALLSLLFSETSWHYFLHISLGLGSTHLTRDG--------ERKSMSVERTFSEINKAEEQYSLCQELCSELAQDLQKERL 451

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BLAST of DNA polymerase kappa vs. Ensembl Human
Match: POLK (DNA polymerase kappa [Source:HGNC Symbol;Acc:HGNC:9183])

HSP 1 Score: 306.22 bits (783), Expect = 3.933e-97
Identity = 176/414 (42.51%), Postives = 255/414 (61.59%), Query Frame = 3

Query:   81 LSSLKVNDNKAGMENLDKKKINETILEASRGSKYYEHEVXXXXXXXXXXXXXXXXYNSLSENDILRGVKKANKLLENISINRNLNQTFVHIDMDAYFAAVEINDNPSLRTKPMAVGSSSMLSTSNYVARKFGVRAGMPGFIAKKLCPDIILIEPNFNKYISISRIFRKIFLDYDINYSACGLDEATLDITEHLKNRISY-SDKQRTF-SCNVSCECRIPIQINSKQTK--------LFK----------------ICDECGKLIGAQEKTFSISSWSAVEELRFRIFARTQLTSSAGMASNGLLAKIVSDINKPNGQYHLSSDPWDINVFIKQLPVGKVPGIGKVSERKLDVLGIVKCEDFYHKRGALYHLFKPCMFSYFMRISLGXXXXXXXXXXXXXXXNGIDRKSMSVERT 1244
            L  + +NDNKAGME LDK+KIN+ I+EA++GS++Y +E+KK K+  +++  + ++   ++   + +   + ++    +  +RNL+ T VHIDMDA++AAVE+ DNP L+ KP+AVGS SMLSTSNY AR+FGVRA MPGFIAK+LCP +I++ PNF+KY ++S+  ++I  DYD N+ A  LDEA L+IT+HL+ R ++  DK+R F     S E   P +  +K ++        LF+                  ++    I      F  S+   V+E+RFRI  +T LT+SAG+A N +LAK+ SD NKPNGQY +  +   +  FIK LP+ KV GIGKV+E+ L  LGI+ C + Y +R  L  LF    + YF+ ISLG GS   +           +RKSMSVER 
Sbjct:   16 LLRMGLNDNKAGMEGLDKEKINKIIMEATKGSRFYGNELKKEKQVNQRIENMMQQKAQITSQQLRKAQLQVDRFAMELEQSRNLSNTIVHIDMDAFYAAVEMRDNPELKDKPIAVGSMSMLSTSNYHARRFGVRAAMPGFIAKRLCPQLIIVPPNFDKYRAVSKEVKEILADYDPNFMAMSLDEAYLNITKHLEERQNWPEDKRRYFIKMGSSVENDNPGKEVNKLSEHERSISPLLFEESPSDVQPPGDPFQVNFEEQNNPQILQNSVVFGTSAQEVVKEIRFRIEQKTTLTASAGIAPNTMLAKVCSDKNKPNGQYQILPNRQAVMDFIKDLPIRKVSGIGKVTEKMLKALGIITCTELYQQRALLSLLFSETSWHYFLHISLGLGSTHLTRDG--------ERKSMSVERV 421

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BLAST of DNA polymerase kappa vs. Ensembl Celegans
Match: polk-1 (DNA polymerase kappa [Source:UniProtKB/Swiss-Prot;Acc:P34409])

HSP 1 Score: 301.212 bits (770), Expect = 1.690e-93
Identity = 215/580 (37.07%), Postives = 313/580 (53.97%), Query Frame = 3

Query:   90 LKVNDNKAGMENLDKKKINETILEASRGSKYYEHEVXXXXXXXXXXXXXXXXYNSLSENDILRGVKKANKLLENISI----NRNLNQTFVHIDMDAYFAAVEINDNPSLRTKPMAVGSSSMLSTSNYVARKFGVRAGMPGFIAKKLCPDIILIEPNFNKYISISRIFRKIFLDYDINYSACGLDEATLDITEHLKNRISYSDKQRTFSCNV---SCECRIP-IQINSKQTKLFK----ICDECGK--LIGAQEKTFSISSWSAVEELRFRIFARTQLTSSAGMASNGLLAKIVSDINKPNGQYHLSSDPWDINVFIKQLPVGKVPGIGKVSERKLDVLGIVKCEDFYHKRGALYHLFKPCMFSYFMRISLGXXXXXXXXXXXXXXXNGIDRKSMSVERTFPDCNDPILLMEKCKTLCKDLWKELLKKNLL-GKCISIKLKLSSFEVRTRAFSNLEATNDLNNITNCACELLQTEINNNQPHKLCLRLLGVRISVLSMKLSPLATLTQLNIKEAFKNQEMKAESTKKEEGVNHEEQLKEKCSSE-----VIKDDSIVQCPVCFVSVN--ISNINTHLDFCI 1763
            L  NDNKAGM  LDK+KI + I E +  S Y     K+    E+++L +K +  + +  +     +K+  L+EN+ +    +R+L++  V IDMDAYFAAVE+ DNP+LRT PMAVGSS+MLSTSNY+AR+FGVRAGMPGFI+ KLCP + ++  N+ KY  +SR F +IF++YD +     LDEA +D+T++    ++ + +++TF  +     C C +P    N    +  K    IC +C K   I      F      AV E+RFR+   T LT SAG+ASN +LAKI SD+NKPNGQY L +D   I  F+K LP+ KV GIG+V E +L  + I    D   K+      F P     F+R +LG                   RKS+SVERTF   +D  +L+E+ + +C+ L +++ K  ++ GK +++KLKLSSF+V TR+ +  +    L +I   + ELL+ E          +RLLGVR+S L                  F+  E K   T  E     + Q++    SE      +       CP+C   V   +  +N H+D CI
Sbjct:    2 LTFNDNKAGMNGLDKEKITKVIEENTSAS-YSSFSKKQQSRIEEKVLEIKNRLQTATREE----RQKSEILMENLEMKLESSRDLSRDCVCIDMDAYFAAVEMRDNPALRTVPMAVGSSAMLSTSNYLARRFGVRAGMPGFISNKLCPSLTIVPGNYPKYTKVSRQFSQIFMEYDSDVGMMSLDEAFIDLTDY----VASNTEKKTFKRHRFGGDCPCWLPRFDENENTLEDLKIEESICPKCEKSRKIYYDHVEFGTGREEAVREIRFRVEQLTGLTCSAGIASNFMLAKICSDLNKPNGQYVLENDKNAIMEFLKDLPIRKVGGIGRVCEAQLKAMDIQTVGDMNLKKNLYPLCFTPLSQESFLRTALGLPGRPSESDPR--------RKSISVERTFSPTSDFNILLEEHQEICRMLEEDVRKSGIVGGKTVTLKLKLSSFDVLTRSLTPSDVVKSLEDIQKFSLELLEKEKGKE------IRLLGVRLSQL-----------------IFEEDEKKRSKTITEFWNEKKLQIQNLQGSENVDDDDVIMMDTRPCPICGTDVENRLDVMNCHVDECI 541

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BLAST of DNA polymerase kappa vs. Ensembl Celegans
Match: polk-1 (DNA polymerase kappa [Source:UniProtKB/Swiss-Prot;Acc:P34409])

HSP 1 Score: 197.978 bits (502), Expect = 3.587e-56
Identity = 148/443 (33.41%), Postives = 219/443 (49.44%), Query Frame = 3

Query:  489 MPGFIAKKLCPDIILIEPNFNKYISISRIFRKIFLDYDINYSACGLDEATLDITEHLKNRISYSDKQRTFS---CNVSCECRIP-IQINSKQTKLFKI----CDECGK--LIGAQEKTFSISSWSAVEELRFRIFARTQLTSSAGMASNGLLAKIVSDINKPNGQYHLSSDPWDINVFIKQLPVGKVPGIGKVSERKLDVLGIVKCEDFYHKRGALYHLFKPCMFSYFMRISLGXXXXXXXXXXXXXXXNGIDRKSMSVERTFPDCNDPILLMEKCKTLCKDLWKELLKKNLL-GKCISIKLKLSSFEVRTRAFSNLEATNDLNNITNCACELLQTEINNNQPHKLCLRLLGVRISVLSMKLSPLATLTQLNIKEAFKNQEMKAESTKKEEGVNHEEQLKEKCSSE-----VIKDDSIVQCPVCFVSVN--ISNINTHLDFCI 1763
            MPGFI+ KLCP + ++  N+ KY  +SR F +IF++YD +     LDEA +D+T++    ++ + +++TF        C C +P    N    +  KI    C +C K   I      F      AV E+RFR+   T LT SAG+ASN +LAKI SD+NKPNGQY L +D   I  F+K LP+ KV GIG+V E +L  + I    D   K+      F P     F+R +LG                   RKS+SVERTF   +D  +L+E+ + +C+ L +++ K  ++ GK +++KLKLSSF+V TR+ +  +    L +I   + ELL+ E          +RLLGVR+S L                  F+  E K   T  E     + Q++    SE      +       CP+C   V   +  +N H+D CI
Sbjct:    1 MPGFISNKLCPSLTIVPGNYPKYTKVSRQFSQIFMEYDSDVGMMSLDEAFIDLTDY----VASNTEKKTFKRHRFGGDCPCWLPRFDENENTLEDLKIEESICPKCEKSRKIYYDHVEFGTGREEAVREIRFRVEQLTGLTCSAGIASNFMLAKICSDLNKPNGQYVLENDKNAIMEFLKDLPIRKVGGIGRVCEAQLKAMDIQTVGDMNLKKNLYPLCFTPLSQESFLRTALGLPGRPSESDPR--------RKSISVERTFSPTSDFNILLEEHQEICRMLEEDVRKSGIVGGKTVTLKLKLSSFDVLTRSLTPSDVVKSLEDIQKFSLELLEKEKGKE------IRLLGVRLSQL-----------------IFEEDEKKRSKTITEFWNEKKLQIQNLQGSENVDDDDVIMMDTRPCPICGTDVENRLDVMNCHVDECI 408

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BLAST of DNA polymerase kappa vs. Ensembl Celegans
Match: polh-1 (DNA polymerase eta; POLH (DNA polymerase eta) homolog [Source:UniProtKB/TrEMBL;Acc:G5EFY1])

HSP 1 Score: 70.4774 bits (171), Expect = 2.009e-12
Identity = 68/269 (25.28%), Postives = 117/269 (43.49%), Query Frame = 3

Query:  351 IDMDAYFAAVEINDNPSLRTKPMAV------GSSSMLSTSNYVARKFGVRAGMPGFIAKKLCPDIILIEPNFNKYI----------SISRIFRKIFLDYD--INYSACGLDEATLDITEHLKNRISYSDKQRTFSCNVSCE------CRIPIQINSKQTKLFK---ICDECGKLIGAQEKTFSISSWSAVEELRFRIFARTQLTSSAGMASNGLLAKIVSDINKPNGQYHLSSDPW-DINVFIKQLPVGKVPGI-GKVSERKLDVLGIV 1070
            IDMD ++A VE  DNPSL  +P+ V      G    +   +Y AR FGV+ GM    AK  CP I +      +Y+          + + +FR +  +YD  I      +DEA LD++ +   ++    +       +           +    + K+ +  +   + +         E    + +   VE++R +I   TQ   SAG+ +N ++AK+V   +KP  Q  +   PW  +   ++  P+G V G  GK+  R  ++L I 
Sbjct:    8 IDMDCFYAQVEQRDNPSLWGQPVIVVQHSRQGIEGGILAVSYEARPFGVKRGMTVAEAKLKCPQISICHVPIGEYVDKADIQKYRDASAEVFR-VLNNYDSQIIIEKASVDEAFLDLSAYTNQKLQELRENEGLEEFLQAAITYLPTTHLATGEDVKENEHLREDVLLEYIENARNCTENLLLLIAAVTVEQIRQQIHEETQFFCSAGVGNNKMMAKLVCARHKPRQQTLI---PWFYVREILRLTPIGDVRGFGGKMGNRIQEMLNIT 272

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BLAST of DNA polymerase kappa vs. Ensembl Celegans
Match: rev-1 (DNA repair protein REV1 [Source:UniProtKB/TrEMBL;Acc:Q09615])

HSP 1 Score: 69.3218 bits (168), Expect = 6.074e-12
Identity = 68/285 (23.86%), Postives = 117/285 (41.05%), Query Frame = 3

Query:  339 TFVHIDMDAYFAAVEINDNPSLRTKPMAVGSS--------SMLSTSNYVARKFGVRAGMPGFIAKKLCPDIILIEPNFNKYISISRIFRKIFLDYDINYSACGLDEATLDITEHLKNRISYSDKQRTFSCNVSCECRIPIQINSKQTKLFKICDECGKLIGAQEKTFSISSWSAVEELRFRIFARTQLTSSAGMASNGLLAKIVSDINKPNGQYHLSSDPWDINVFIKQLPVGKVPGIG-KVSERKLDVLG-IVKCEDFYHK-RGALYHLFKPCMFSYFMRISLG 1160
            T  H+D+D +F +V + +   L+ K +A+  S        S +++ +Y AR  GV+ GM    A + CP + L+   F  Y+ +SR   +I   Y +   A   DE  ++++       S+ +K                         ++I D                     E +R  I  +TQ  +S G+ S  LLA++ +   KP+G + +++     N FI +  V  +PG G ++  R     G I KC +   K    L  +F P + S  +R   G
Sbjct:  439 TVFHVDLDCFFVSVAVRNRIDLKHKEVAITHSKGTISNSMSEVASCSYAARDCGVKNGMLVRDALQKCPQLTLLPYQFEDYVQVSRKIYEILASYTLEVRAVSCDEMYINMS-------SFCEK-------------------------YEINDPT----------------ILAEHIRKVIREKTQCPASVGIGSTSLLARLATRHAKPDGVFWVNAHKK--NEFISEEKVKDLPGFGYEMMNRLTSFFGDITKCRELQLKTERELVPVFGPKLASKILRQCRG 673

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BLAST of DNA polymerase kappa vs. Ensembl Fly
Match: DNApol-iota (gene:FBgn0037554 transcript:FBtr0081797)

HSP 1 Score: 82.8037 bits (203), Expect = 3.981e-16
Identity = 73/256 (28.52%), Postives = 124/256 (48.44%), Query Frame = 3

Query:  333 NQTFVHIDMDAYFAAVEINDNPSLRTKPMAVGSSSMLSTSNYVARKFGVRAGMPGFIAKKLCPDIILIE-PNFNKYISISRIFRKIFLDYDINYSACGLDEATLDITEHLKNRISYSDKQRTFSCNVSCECRIPI-QINSKQTKLFKICDECGKLIGAQEKTFSISSWSAVEELRFRIFARTQLTSSAGMASNGLLAKIVSDINKPNGQYHLSSDPWDINVFIKQL-PVGKVPGIGKVSERKLDVLGIVKCEDFYH 1091
             +T +H+DMD ++A VE   +P+LR+K + +   +++ T NYVAR  GV   M    A+++CPD++L+   +   Y  +S+    + L+Y       G DE  +D+T  ++ R ++               R P+             CD CG    AQ    +I +  A +E+R  +  R  +T  AG+A N LLAK+V   ++PN Q  L S   +   F+++L  + +V GIG+ ++  L   G+   E    
Sbjct:   14 QRTIIHLDMDYFYAQVEEIRDPTLRSKALGIQQKNIVVTCNYVARAKGVTKLMLIAEAQRICPDLVLVNGEDLAPYRQMSQRIFDLLLNYTPLVEKLGFDENFMDVTALVELRQAHV---------AEALLRPPVGHTYPADGTPLSNCD-CG---CAQR--LAIGTRIA-QEIREELKLRLGITCCAGIAYNKLLAKLVGSSHEPNQQTVLVSTYAE--QFMRELGDLKRVTGIGQKTQCLLLEAGMSSVEQLQQ 251

[Close]

BLAST of DNA polymerase kappa vs. Ensembl Fly
Match: DNApol-iota (gene:FBgn0037554 transcript:FBtr0081798)

HSP 1 Score: 82.8037 bits (203), Expect = 3.981e-16
Identity = 73/256 (28.52%), Postives = 124/256 (48.44%), Query Frame = 3

Query:  333 NQTFVHIDMDAYFAAVEINDNPSLRTKPMAVGSSSMLSTSNYVARKFGVRAGMPGFIAKKLCPDIILIE-PNFNKYISISRIFRKIFLDYDINYSACGLDEATLDITEHLKNRISYSDKQRTFSCNVSCECRIPI-QINSKQTKLFKICDECGKLIGAQEKTFSISSWSAVEELRFRIFARTQLTSSAGMASNGLLAKIVSDINKPNGQYHLSSDPWDINVFIKQL-PVGKVPGIGKVSERKLDVLGIVKCEDFYH 1091
             +T +H+DMD ++A VE   +P+LR+K + +   +++ T NYVAR  GV   M    A+++CPD++L+   +   Y  +S+    + L+Y       G DE  +D+T  ++ R ++               R P+             CD CG    AQ    +I +  A +E+R  +  R  +T  AG+A N LLAK+V   ++PN Q  L S   +   F+++L  + +V GIG+ ++  L   G+   E    
Sbjct:   14 QRTIIHLDMDYFYAQVEEIRDPTLRSKALGIQQKNIVVTCNYVARAKGVTKLMLIAEAQRICPDLVLVNGEDLAPYRQMSQRIFDLLLNYTPLVEKLGFDENFMDVTALVELRQAHV---------AEALLRPPVGHTYPADGTPLSNCD-CG---CAQR--LAIGTRIA-QEIREELKLRLGITCCAGIAYNKLLAKLVGSSHEPNQQTVLVSTYAE--QFMRELGDLKRVTGIGQKTQCLLLEAGMSSVEQLQQ 251

[Close]

BLAST of DNA polymerase kappa vs. Ensembl Fly
Match: DNApol-iota (gene:FBgn0037554 transcript:FBtr0339606)

HSP 1 Score: 82.8037 bits (203), Expect = 3.981e-16
Identity = 73/256 (28.52%), Postives = 124/256 (48.44%), Query Frame = 3

Query:  333 NQTFVHIDMDAYFAAVEINDNPSLRTKPMAVGSSSMLSTSNYVARKFGVRAGMPGFIAKKLCPDIILIE-PNFNKYISISRIFRKIFLDYDINYSACGLDEATLDITEHLKNRISYSDKQRTFSCNVSCECRIPI-QINSKQTKLFKICDECGKLIGAQEKTFSISSWSAVEELRFRIFARTQLTSSAGMASNGLLAKIVSDINKPNGQYHLSSDPWDINVFIKQL-PVGKVPGIGKVSERKLDVLGIVKCEDFYH 1091
             +T +H+DMD ++A VE   +P+LR+K + +   +++ T NYVAR  GV   M    A+++CPD++L+   +   Y  +S+    + L+Y       G DE  +D+T  ++ R ++               R P+             CD CG    AQ    +I +  A +E+R  +  R  +T  AG+A N LLAK+V   ++PN Q  L S   +   F+++L  + +V GIG+ ++  L   G+   E    
Sbjct:   14 QRTIIHLDMDYFYAQVEEIRDPTLRSKALGIQQKNIVVTCNYVARAKGVTKLMLIAEAQRICPDLVLVNGEDLAPYRQMSQRIFDLLLNYTPLVEKLGFDENFMDVTALVELRQAHV---------AEALLRPPVGHTYPADGTPLSNCD-CG---CAQR--LAIGTRIA-QEIREELKLRLGITCCAGIAYNKLLAKLVGSSHEPNQQTVLVSTYAE--QFMRELGDLKRVTGIGQKTQCLLLEAGMSSVEQLQQ 251

[Close]

BLAST of DNA polymerase kappa vs. Ensembl Fly
Match: DNApol-eta (gene:FBgn0037141 transcript:FBtr0078489)

HSP 1 Score: 78.9518 bits (193), Expect = 7.674e-15
Identity = 74/283 (26.15%), Postives = 123/283 (43.46%), Query Frame = 3

Query:  309 NISINRNLNQTFVHIDMDAYFAAVEINDNPSLRTKPMAV-----GSSSMLSTSNYVARKFGVRAGMPGFIAKKLCPDIILIE-PNF------NKYISISRIFRKIFLDYDINYSACGLDEATLDITEHLKNRISY----------SDKQRTFSCNVSCECRIPIQINSK------QTKLFKICDECGKLIGAQEKTFSISSWSAVE-ELRFRIFARTQLTSSAGMASNGLLAKIVSDINKPNGQYHLSSDPWDINVFIKQLPVGKVPGI-GKVSERKLDVLGI 1067
            ++S+    ++  + +DMD +F  VE   +P  R +P+AV          +   NY AR  GV   M G  AK LCP+I+L + PN       +KY    +    +   +        +DEA LDITE + +R+             +   TF+           +I ++        + +++  +   L   ++    +   ++V  E+R  +   T    SAG+A N +LAK+ + +NKPN Q  L     +       LPVGK+ G+ GK  E   + LGI
Sbjct:    7 HVSMQNKYDRVVLLVDMDCFFCQVEEKQHPEYRNRPLAVVQYNPWRGGGIIAVNYAARAKGVTRHMRGDEAKDLCPEIVLCQVPNIREKADTSKYRDAGKEVANVLQRFTQLLERASVDEAYLDITETVNHRMQQMQSGAFALQPQELVNTFAVGYPSIGDYVNKITNRFANPYMDDERYQMSYDQNDLPAVRQSDIRLLIGASVAGEVRAAVKKETGYECSAGIAHNKILAKLAAGMNKPNKQTILPL--TETASLFDSLPVGKIKGLGGKFGEVVCETLGI 287

[Close]

BLAST of DNA polymerase kappa vs. Ensembl Fly
Match: Rev1 (gene:FBgn0035150 transcript:FBtr0072557)

HSP 1 Score: 67.3958 bits (163), Expect = 3.568e-11
Identity = 66/302 (21.85%), Postives = 104/302 (34.44%), Query Frame = 3

Query:  330 LNQTFVHIDMDAYFAAVEINDNPSLRTKPMAVGSS---------------------------------------------------SMLSTSNYVARKFGVRAGMPGFIAKKLCPDIILIEPNFNKYISISRIFRKIFLDYDINYSACGLDEATLDITEHLKNRISYSDKQRTFSCNVSCECRIPIQINSKQTKLFKICDECGKLIGAQEKTFSISSWSAVEELRFRIFARTQLTSSAGMASNGLLAKIVSDINKPNGQYHLSSDPWDINVFIKQLPVGKVPGIGKVSERKLDVLGIVKCED 1082
            L +  +HIDMD +F +V +   P LR  P+AV  S                                                   S +++ +Y AR+ G+R GM    A KLCP++  I  +F  Y  ++         Y +N  A                                                   CDE    +       ++   + V  LR  ++++T    SAG+A N LLA++ +   KPNGQ+ L S   DI  ++  + +  +PG+G     KL   G+  C D
Sbjct:  271 LERYVMHIDMDCFFVSVGLRTRPELRGLPIAVTHSKGGNAATDVPVHPQADRKAELELFAQRFEHHFHDGDKAEKVRSGFDKKMSLSEIASCSYEAREKGIRNGMFVGQALKLCPELKTIPYDFEGYKEVAFTLYDTVAQYTLNIEAVS-------------------------------------------------CDEMFVELTDLAHELNVDVMAFVSHLRQEVYSKTGCPCSAGVAGNKLLARMATKEAKPNGQFLLDSSN-DILAYMAPMSLDLLPGVGSSISHKLKQAGLNNCGD 522

[Close]

BLAST of DNA polymerase kappa vs. Ensembl Zebrafish
Match: polk (polymerase (DNA directed) kappa [Source:ZFIN;Acc:ZDB-GENE-060526-137])

HSP 1 Score: 377.096 bits (967), Expect = 2.749e-119
Identity = 211/481 (43.87%), Postives = 294/481 (61.12%), Query Frame = 3

Query:   81 LSSLKVNDNKAGMENLDKKKINETILEASRGSKYYEHEVXXXXXXXXXXXXXXXXYNSLSENDILRGVKKANKLLENISINRNLNQTFVHIDMDAYFAAVEINDNPSLRTKPMAVGSSSMLSTSNYVARKFGVRAGMPGFIAKKLCPDIILIEPNFNKYISISRIFRKIFLDYDINYSACGLDEATLDITEHLKNRISYSDKQRTFSCNVSCECRIPIQINSKQTKLFKICDECGKLIGAQEKTFSISSWSAVEELRFRIFARTQLTSSAGMASNGLLAKIVSDINKPNGQYHLSSDPWDINVFIKQLPVGKVPGIGKVSERKLDVLGIVKCEDFYHKRGALYHLFKPCMFSYFMRISLGXXXXXXXXXXXXXXXNGIDRKSMSVERTFPDCNDPILLMEKCKTLCKDLWKELLKKNLLGKCISIKLKLSSFEVRTRAFSNLEATNDLNNITNCACELLQTEINNNQPHKLCLRLLGVRIS 1523
            LS + +NDNKAGME LD+ KIN+ ILE S+GS++YE+E+KK ++  +++  + E+   +++  + +   + ++L  ++  +R L +  VH+DMDA++AAVE+ D P L+ KPMAVGS SMLSTSNY AR+FGVRA MPGFIAKKLCPD++++  NF+KY ++S   R+IF +YD N+    LDEA LDITEHL+ R  + D  RT                       KICD      G  E  F  S+  AV E+RFRI  +T LT+SAG+A N +LAK+ SD NKPNGQY +  +   +  F+K LPV KV G+GKV+E+ L  LGIV C     +   L  LF    + +F+ ISLG GS               +RKSMS ERTF + +D       CK LC DL ++L ++ L GK +++KLK   FEV+T+AF+   A      I   A +LL+ EI++  P  L LRL+GVR+S
Sbjct:   16 LSRIALNDNKAGMEGLDRDKINKIILETSKGSRFYENELKKERQVNQRIEKMMEQKAKITKEQMKQAQAEVDRLTVDLERSRELGRVIVHVDMDAFYAAVEMRDCPELKDKPMAVGSMSMLSTSNYHARRFGVRAAMPGFIAKKLCPDLVIVPTNFDKYRAVSAQVREIFSEYDPNFMPMSLDEAYLDITEHLEQRKHWPDTMRT----------------------HKICDAKTGADGKAE-VFGTSAEEAVREMRFRIEQKTSLTASAGIAPNMMLAKVCSDKNKPNGQYRIPPERQVVMDFMKDLPVRKVSGVGKVTEKMLAALGIVTCSQLGQQMALLSLLFSETSWHHFLHISLGLGSTYMERDS--------ERKSMSTERTFGEMSDAGEQYSLCKELCHDLAQDLQREGLKGKTVTLKLKNVKFEVKTKAFTLQYAVCTEEEIFAAAKDLLKVEIDSVSPQPLKLRLMGVRVS 465

[Close]

BLAST of DNA polymerase kappa vs. Ensembl Zebrafish
Match: polk (polymerase (DNA directed) kappa [Source:ZFIN;Acc:ZDB-GENE-060526-137])

HSP 1 Score: 374.4 bits (960), Expect = 4.858e-118
Identity = 216/492 (43.90%), Postives = 305/492 (61.99%), Query Frame = 3

Query:   81 LSSLKVNDNKAGMENLDKKKINETILEASRGSKYYEHEVXXXXXXXXXXXXXXXXYNSLSENDILRGVKKANKLLENISINRNLNQTFVHIDMDAYFAAVEINDNPSLRTKPMAVGSSSMLSTSNYVARKFGVRAGMPGFIAKKLCPDIILIEPNFNKYISISRIFRKIFLDYDINYSACGLDEATLDITEHLKNRISYSDKQRTFS-CNVSCE---CRIPIQINSKQTKLFKICDE-----CGKLIGAQEKT--FSISSWSAVEELRFRIFARTQLTSSAGMASNGLLAKIVSDINKPNGQYHLSSDPWDINVFIKQLPVGKVPGIGKVSERKLDVLGIVKCEDFYHKRGALYHLFKPCMFSYFMRISLGXXXXXXXXXXXXXXXNGIDRKSMSVERTFPDCNDPILLMEKCKTLCKDLWKELLKKNLLGKCISIKLKLSSFEVRTRAFSNLEATNDLNNITNCACELLQTEINNNQPHKLCLRLLGVRIS 1523
            LS + +NDNKAGME LD+ KIN+ ILE S+GS++YE+E+KK ++  +++  + E+   +++  + +   + ++L  ++  +R L +  VH+DMDA++AAVE+ D P L+ KPMAVGS SMLSTSNY AR+FGVRA MPGFIAKKLCPD++++  NF+KY ++S   R+IF +YD N+    LDEA LDITEHL+ R  + D  RT   C+   E   CR   +  S++ +L  +  E        L GA  K   F  S+  AV E+RFRI  +T LT+SAG+A N +LAK+ SD NKPNGQY +  +   +  F+K LPV KV G+GKV+E+ L  LGIV C     +   L  LF    + +F+ ISLG GS               +RKSMS ERTF + +D       CK LC DL ++L ++ L GK +++KLK   FEV+T+AF+   A      I   A +LL+ EI++  P  L LRL+GVR+S
Sbjct:   29 LSRIALNDNKAGMEGLDRDKINKIILETSKGSRFYENELKKERQVNQRIEKMMEQKAKITKEQMKQAQAEVDRLTVDLERSRELGRVIVHVDMDAFYAAVEMRDCPELKDKPMAVGSMSMLSTSNYHARRFGVRAAMPGFIAKKLCPDLVIVPTNFDKYRAVSAQVREIFSEYDPNFMPMSLDEAYLDITEHLEQRKHWPDTMRTHKICDAKTESDACRSTSE--SERDELSPVLFEDSPSSSPSLSGADGKAEVFGTSAEEAVREMRFRIEQKTSLTASAGIAPNMMLAKVCSDKNKPNGQYRIPPERQVVMDFMKDLPVRKVSGVGKVTEKMLAALGIVTCSQLGQQMALLSLLFSETSWHHFLHISLGLGSTYMERDS--------ERKSMSTERTFGEMSDAGEQYSLCKELCHDLAQDLQREGLKGKTVTLKLKNVKFEVKTKAFTLQYAVCTEEEIFAAAKDLLKVEIDSVSPQPLKLRLMGVRVS 510

[Close]

BLAST of DNA polymerase kappa vs. Ensembl Zebrafish
Match: poli (polymerase (DNA directed) iota [Source:ZFIN;Acc:ZDB-GENE-050417-376])

HSP 1 Score: 107.457 bits (267), Expect = 8.689e-24
Identity = 80/252 (31.75%), Postives = 122/252 (48.41%), Query Frame = 3

Query:  336 QTFVHIDMDAYFAAVEINDNPSLRTKPMAVGSSSMLSTSNYVARKFGVRAGMPGFIAKKLCPDIILIE-PNFNKYISISRIFRKIFLDYDINYSACGLDEATLDITEHLKNRISYSDKQRTFSCNVSCECRIPIQINSKQTKLFKICDECGKLIGAQEKTFSISSWSAVEELRFRIFARTQLTSSAGMASNGLLAKIVSDINKPNGQYHLSSDPWDINVFIKQLP-VGKVPGIGKVSERKLDVLGIVKCEDF 1085
            +  +H D+D ++A VE+  NP+LRTKP+ +    ++ TSNYVAR+ GV   M    A + CP ++L++  +   Y  +S    ++ + Y       G DE  +D+TE ++ RI  + +    S N        + ++ +  +L       G +I A              E+R  IF+   LT  AG+ASN LLAK+VS   KPN Q  L   P      +  L  + KVPGIG  +  KL  LG+V   D 
Sbjct:   37 RVILHFDLDCFYAQVEMIRNPALRTKPLGIQQKYIIVTSNYVARELGVNKLMSVTDAVEKCPQLVLVKGEDLTHYREMSYKVTELLMSYCPLVERLGFDENFMDVTEMVEKRIKET-RISDLSFNGHVYNHESVVVDEENIRL-----AVGSVIAA--------------EMRQAIFSTLGLTGCAGVASNKLLAKLVSGSFKPNQQTTLL--PHSTAELMSSLTGLIKVPGIGYKTREKLKALGLVNVRDL 266

[Close]

BLAST of DNA polymerase kappa vs. Ensembl Zebrafish
Match: rev1 (REV1 DNA directed polymerase [Source:ZFIN;Acc:ZDB-GENE-081105-180])

HSP 1 Score: 79.337 bits (194), Expect = 1.011e-14
Identity = 63/222 (28.38%), Postives = 96/222 (43.24%), Query Frame = 3

Query:  417 MAVGSSSMLSTSNYVARKFGVRAGMPGFIAKKLCPDIILIEPNFNKYISISRIFRKIFLDYDINYSACGLDEATLDITEHLKNRISYSDKQRTFSCNVSCECRIPIQINSKQTKLFKICDECGKLIGAQEKTFSISSWSAVEELRFRIFARTQLTSSAGMASNGLLAKIVSDINKPNGQYHLSSDPWDINVFIKQLPVGKVPGIGKVSERKLDVLGIVKCED 1082
            +A  S + +++ +Y AR+ GVR GM    AK+LCPD+  +  +F+ Y  ++    +I   Y  N  A   DEA +D T  L                                +L    DE  + I                  R  I  +T   +S GM+SN LLA++ +   KP GQY L S+  +++ FI+  PV  +PG+G+    KL  LG+  C D
Sbjct:  539 LAALSMAEIASCSYEARQAGVRNGMFFGRAKQLCPDLQSVPYDFHAYKEVALAMYEILASYTHNIEALSCDEALVDATALL-------------------------------VELGVSPDELARSI------------------REDIKEKTGCCASVGMSSNILLARMATRKAKPKGQYLLRSE--EVDDFIRDQPVSSLPGVGRSMSSKLTSLGVSTCGD 709

[Close]

Query:  417 MAVGSSSMLSTSNYVARKFGVRAGMPGFIAKKLCPDIILIEPNFNKYISISRIFRKIFLDYDINYSACGLDEATLDITEHLKNRISYSDKQRTFSCNVSCECRIPIQINSKQTKLFKICDECGKLIGAQEKTFSISSWSAVEELRFRIFARTQLTSSAGMASNGLLAKIVSDINKPNGQYHLSSDPWDINVFIKQLPVGKVPGIGKVSERKLDVLGIVKCED 1082
            +A  S + +++ +Y AR+ GVR GM    AK+LCPD+  +  +F+ Y  ++    +I   Y  N  A   DEA +D T  L                                +L    DE  + I                  R  I  +T   +S GM+SN LLA++ +   KP GQY L S+  +++ FI+  PV  +PG+G+    KL  LG+  C D
Sbjct:  539 LAALSMAEIASCSYEARQAGVRNGMFFGRAKQLCPDLQSVPYDFHAYKEVALAMYEILASYTHNIEALSCDEALVDATALL-------------------------------VELGVSPDELARSI------------------REDIKEKTGCCASVGMSSNILLARMATRKAKPKGQYLLRSE--EVDDFIRDQPVSSLPGVGRSMSSKLTSLGVSTCGD 709

[Close]

BLAST of DNA polymerase kappa vs. Ensembl Xenopus
Match: sec31a (SEC31 homolog A, COPII coat complex component [Source:Xenbase;Acc:XB-GENE-5955093])

HSP 1 Score: 376.711 bits (966), Expect = 3.949e-123
Identity = 214/510 (41.96%), Postives = 309/510 (60.59%), Query Frame = 3

Query:   90 LKVNDNKAGMENLDKKKINETILEASRGSKYYEHEVXXXXXXXXXXXXXXXXYNSLSENDILRGVKKANKLLENISINRNLNQTFVHIDMDAYFAAVEINDNPSLRTKPMAVGSSSMLSTSNYVARKFGVRAGMPGFIAKKLCPDIILIEPNFNKYISISRIFRKIFLDYDINYSACGLDEATLDITEHLKNRISYSDKQRTFSCNVS--------------CECRIPIQINSKQTKLFKICDE--CGKLIGAQEK----------TFSISSWSAVEELRFRIFARTQLTSSAGMASNGLLAKIVSDINKPNGQYHLSSDPWDINVFIKQLPVGKVPGIGKVSERKLDVLGIVKCEDFYHKRGALYHLFKPCMFSYFMRISLGXXXXXXXXXXXXXXXNGIDRKSMSVERTFPDCNDPILLMEKCKTLCKDLWKELLKKNLLGKCISIKLKLSSFEVRTRAFSNLEATNDLNNITNCACELLQTEINNNQPHKLCLRLLGVRISVLSMKL 1541
            + +NDNKAGME LDK+KIN+ I++A++GS++Y++E+KK ++  +++  L ++ + L++  I +   + ++L   +  NR+L++  VH+DMDA++AAVE+ D+P L+ KPMAVGS+SMLSTSNY+AR+FGVRA MPGFIAKKLCP + ++ PNF+KY ++S   R+I   YD N+    LDEA LDIT+HL  R+++ + +RTF    +               EC  P+      +    + D+      +G  E+           F  S   AV+E+RFRI  +T LT+SAG+A N +LAK+ SD NKPNGQY + +D   I  FIK LP+ KVPGIGKV+E+ L  LGI+ C D Y +R  L  LF    +  F+ ISLG GS               +RKSMS ERTF + +      + C+ LC+DL ++L K+ L GK ++IKLK   FEVRTRA +     +    I   A E+L+ EI+   P  L LRL+G   S +  KL
Sbjct:   19 MGLNDNKAGMEGLDKEKINKIIMDATKGSRFYDNELKKDQQVNQRIEKLMQQKSQLTDQQIKKAQIQVDRLALELERNRDLSRIIVHVDMDAFYAAVEMRDSPELKDKPMAVGSNSMLSTSNYLARRFGVRAAMPGFIAKKLCPTLKIVPPNFDKYRAVSSEVREILAQYDPNFLPMSLDEAYLDITDHLSERLAWPEDKRTFMIRTNNSGGNKPLPGKQEQVECTSPVLFEDSPS---FVADQNFSQPGLGTTEENRKPSLENVVVFGTSVEEAVKEMRFRIEQKTTLTASAGIAPNMMLAKVCSDKNKPNGQYRIFNDKQAIKDFIKDLPIRKVPGIGKVTEKMLKALGIITCTDLYQQRALLSLLFSETSWQNFVHISLGLGSTHVERDG--------ERKSMSTERTFSEISSSEEQYDLCQELCRDLAQDLQKEGLKGKTVTIKLKNVKFEVRTRALTVGSTVSTEEEIFAVAKEILKAEIDLASPEPLRLRLMGGACSCIDYKL 517

[Close]

BLAST of DNA polymerase kappa vs. Ensembl Xenopus
Match: sec31a (SEC31 homolog A, COPII coat complex component [Source:Xenbase;Acc:XB-GENE-5955093])

HSP 1 Score: 385.185 bits (988), Expect = 7.056e-123
Identity = 246/666 (36.94%), Postives = 364/666 (54.65%), Query Frame = 3

Query:   90 LKVNDNKAGMENLDKKKINETILEASRGSKYYEHEVXXXXXXXXXXXXXXXXYNSLSENDILRGVKKANKLLENISINRNLNQTFVHIDMDAYFAAVEINDNPSLRTKPMAVGSSSMLSTSNYVARKFGVRAGMPGFIAKKLCPDIILIEPNFNKYISISRIFRKIFLDYDINYSACGLDEATLDITEHLKNRISYSDKQRTFSCNVS--------------CECRIPIQINSKQTKLFKICDE--CGKLIGAQEK----------TFSISSWSAVEELRFRIFARTQLTSSAGMASNGLLAKIVSDINKPNGQYHLSSDPWDINVFIKQLPVGKVPGIGKVSERKLDVLGIVKCEDFYHKRGALYHLFKPCMFSYFMRISLGXXXXXXXXXXXXXXXNGIDRKSMSVERTFPDCNDPILLMEKCKTLCKDLWKELLKKNLLGKCISIKLKLSSFEVRTRAFSNLEATNDLNNITNCACELLQTEINNNQPHKLCLRLLGVRISVL------------------------------SMKLSP--LATLTQLNIKEAFKNQEMKAES-------------TKKEEG-VNHEEQLKEKCSSEVIKDDSIVQCPVCFV---SVNISNINTHLDFCI--SPANSEQPSTSTYVPTLKRSAPVNSKSRSKI 1856
            + +NDNKAGME LDK+KIN+ I++A++GS++Y++E+KK ++  +++  L ++ + L++  I +   + ++L   +  NR+L++  VH+DMDA++AAVE+ D+P L+ KPMAVGS+SMLSTSNY+AR+FGVRA MPGFIAKKLCP + ++ PNF+KY ++S   R+I   YD N+    LDEA LDIT+HL  R+++ + +RTF    +               EC  P+      +    + D+      +G  E+           F  S   AV+E+RFRI  +T LT+SAG+A N +LAK+ SD NKPNGQY + +D   I  FIK LP+ KVPGIGKV+E+ L  LGI+ C D Y +R  L  LF    +  F+ ISLG GS               +RKSMS ERTF + +      + C+ LC+DL ++L K+ L GK ++IKLK   FEVRTRA +     +    I   A E+L+ EI+   P  L LRL+GVR+S                                S K +P  LAT  Q   +++F NQ+  A                K E+  ++  E   E    E +       CP+CF+     ++++ N H+D C+  SP +SE  S       +  + P+++   S I
Sbjct:   19 MGLNDNKAGMEGLDKEKINKIIMDATKGSRFYDNELKKDQQVNQRIEKLMQQKSQLTDQQIKKAQIQVDRLALELERNRDLSRIIVHVDMDAFYAAVEMRDSPELKDKPMAVGSNSMLSTSNYLARRFGVRAAMPGFIAKKLCPTLKIVPPNFDKYRAVSSEVREILAQYDPNFLPMSLDEAYLDITDHLSERLAWPEDKRTFMIRTNNSGGNKPLPGKQEQVECTSPVLFEDSPS---FVADQNFSQPGLGTTEENRKPSLENVVVFGTSVEEAVKEMRFRIEQKTTLTASAGIAPNMMLAKVCSDKNKPNGQYRIFNDKQAIKDFIKDLPIRKVPGIGKVTEKMLKALGIITCTDLYQQRALLSLLFSETSWQNFVHISLGLGSTHVERDG--------ERKSMSTERTFSEISSSEEQYDLCQELCRDLAQDLQKEGLKGKTVTIKLKNVKFEVRTRALTVGSTVSTEEEIFAVAKEILKAEIDLASPEPLRLRLMGVRVSGFLTEEEKKHHQKSITGFLHVSKPGSSSSLGQSDKANPSALATGPQ---RQSFFNQKRAAREHMVQEKHAVCSGFVKSEDATISDSEGKTETLDLENVSQKPEFTCPICFLKESDWDLASFNKHIDKCLSRSPISSELESPYKEGAQIGHTRPLDAFDDSGI 670

[Close]

BLAST of DNA polymerase kappa vs. Ensembl Xenopus
Match: sec31a (SEC31 homolog A, COPII coat complex component [Source:Xenbase;Acc:XB-GENE-5955093])

HSP 1 Score: 384.8 bits (987), Expect = 3.486e-122
Identity = 244/646 (37.77%), Postives = 357/646 (55.26%), Query Frame = 3

Query:   90 LKVNDNKAGMENLDKKKINETILEASRGSKYYEHEVXXXXXXXXXXXXXXXXYNSLSENDILRGVKKANKLLENISINRNLNQTFVHIDMDAYFAAVEINDNPSLRTKPMAVGSSSMLSTSNYVARKFGVRAGMPGFIAKKLCPDIILIEPNFNKYISISRIFRKIFLDYDINYSACGLDEATLDITEHLKNRISYSDKQRTFSCNVS--------------CECRIPIQINSKQTKLFK-----ICDE--CGKLIGAQEK----------TFSISSWSAVEELRFRIFARTQLTSSAGMASNGLLAKIVSDINKPNGQYHLSSDPWDINVFIKQLPVGKVPGIGKVSERKLDVLGIVKCEDFYHKRGALYHLFKPCMFSYFMRISLGXXXXXXXXXXXXXXXNGIDRKSMSVERTFPDCNDPILLMEKCKTLCKDLWKELLKKNLLGKCISIKLKLSSFEVRTRAFSNLEATNDLNNITNCACELLQTEINNNQPHKLCLRLLGVRISVL------------------------------SMKLSP--LATLTQLNIKEAFKNQEMKAES-------------TKKEEG-VNHEEQLKEKCSSEVIKDDSIVQCPVCFV---SVNISNINTHLDFCI--SPANSE 1781
            + +NDNKAGME LDK+KIN+ I++A++GS++Y++E+KK ++  +++  L ++ + L++  I +   + ++L   +  NR+L++  VH+DMDA++AAVE+ D+P L+ KPMAVGS+SMLSTSNY+AR+FGVRA MPGFIAKKLCP + ++ PNF+KY ++S   R+I   YD N+    LDEA LDIT+HL  R+++ + +RTF    +               EC  P+        LF+     + D+      +G  E+           F  S   AV+E+RFRI  +T LT+SAG+A N +LAK+ SD NKPNGQY + +D   I  FIK LP+ KVPGIGKV+E+ L  LGI+ C D Y +R  L  LF    +  F+ ISLG GS               +RKSMS ERTF + +      + C+ LC+DL ++L K+ L GK ++IKLK   FEVRTRA +     +    I   A E+L+ EI+   P  L LRL+GVR+S                                S K +P  LAT  Q   +++F NQ+  A                K E+  ++  E   E    E +       CP+CF+     ++++ N H+D C+  SP +SE
Sbjct:   20 MGLNDNKAGMEGLDKEKINKIIMDATKGSRFYDNELKKDQQVNQRIEKLMQQKSQLTDQQIKKAQIQVDRLALELERNRDLSRIIVHVDMDAFYAAVEMRDSPELKDKPMAVGSNSMLSTSNYLARRFGVRAAMPGFIAKKLCPTLKIVPPNFDKYRAVSSEVREILAQYDPNFLPMSLDEAYLDITDHLSERLAWPEDKRTFMIRTNNSGGNKPLPGKQEQVECTSPV--------LFEDSPSFVADQNFSQPGLGTTEENRKPSLENVVVFGTSVEEAVKEMRFRIEQKTTLTASAGIAPNMMLAKVCSDKNKPNGQYRIFNDKQAIKDFIKDLPIRKVPGIGKVTEKMLKALGIITCTDLYQQRALLSLLFSETSWQNFVHISLGLGSTHVERDG--------ERKSMSTERTFSEISSSEEQYDLCQELCRDLAQDLQKEGLKGKTVTIKLKNVKFEVRTRALTVGSTVSTEEEIFAVAKEILKAEIDLASPEPLRLRLMGVRVSGFLTEEEKKHHQKSITGFLHVSKPGSSSSLGQSDKANPSALATGPQ---RQSFFNQKRAAREHMVQEKHAVCSGFVKSEDATISDSEGKTETLDLENVSQKPEFTCPICFLKESDWDLASFNKHIDKCLSRSPISSE 646

[Close]

BLAST of DNA polymerase kappa vs. Ensembl Xenopus
Match: sec31a (SEC31 homolog A, COPII coat complex component [Source:Xenbase;Acc:XB-GENE-5955093])

HSP 1 Score: 382.489 bits (981), Expect = 3.894e-122
Identity = 242/645 (37.52%), Postives = 355/645 (55.04%), Query Frame = 3

Query:   90 LKVNDNKAGMENLDKKKINETILEASRGSKYYEHEVXXXXXXXXXXXXXXXXYNSLSENDILRGVKKANKLLENISINRNLNQTFVHIDMDAYFAAVEINDNPSLRTKPMAVGSSSMLSTSNYVARKFGVRAGMPGFIAKKLCPDIILIEPNFNKYISISRIFRKIFLDYDINYSACGLDEATLDITEHLKNRISYSDKQRTFSCNVS------------------CECRIPIQINSKQTKLFKICDE--CGKLIGAQEK----------TFSISSWSAVEELRFRIFARTQLTSSAGMASNGLLAKIVSDINKPNGQYHLSSDPWDINVFIKQLPVGKVPGIGKVSERKLDVLGIVKCEDFYHKRGALYHLFKPCMFSYFMRISLGXXXXXXXXXXXXXXXNGIDRKSMSVERTFPDCNDPILLMEKCKTLCKDLWKELLKKNLLGKCISIKLKLSSFEVRTRAFSNLEATNDLNNITNCACELLQTEINNNQPHKLCLRLLGVRISVL------------------------------SMKLSP--LATLTQLNIKEAFKNQEMKAES-------------TKKEEG-VNHEEQLKEKCSSEVIKDDSIVQCPVCFV---SVNISNINTHLDFCI--SPANSE 1781
            + +NDNKAGME LDK+KIN+ I++A++GS++Y++E+KK ++  +++  L ++ + L++  I +   + ++L   +  NR+L++  VH+DMDA++AAVE+ D+P L+ KPMAVGS+SMLSTSNY+AR+FGVRA MPGFIAKKLCP + ++ PNF+KY ++S   R+I   YD N+    LDEA LDIT+HL  R+++ + +RTF    +                   EC  P+      +    + D+      +G  E+           F  S   AV+E+RFRI  +T LT+SAG+A N +LAK+ SD NKPNGQY + +D   I  FIK LP+ KVPGIGKV+E+ L  LGI+ C D Y +R  L  LF    +  F+ ISLG GS               +RKSMS ERTF + +      + C+ LC+DL ++L K+ L GK ++IKLK   FEVRTRA +     +    I   A E+L+ EI+   P  L LRL+GVR+S                                S K +P  LAT  Q   +++F NQ+  A                K E+  ++  E   E    E +       CP+CF+     ++++ N H+D C+  SP +SE
Sbjct:   19 MGLNDNKAGMEGLDKEKINKIIMDATKGSRFYDNELKKDQQVNQRIEKLMQQKSQLTDQQIKKAQIQVDRLALELERNRDLSRIIVHVDMDAFYAAVEMRDSPELKDKPMAVGSNSMLSTSNYLARRFGVRAAMPGFIAKKLCPTLKIVPPNFDKYRAVSSEVREILAQYDPNFLPMSLDEAYLDITDHLSERLAWPEDKRTFMIRTNNSGGNKPLPGKKNRIKDLLECTSPVLFEDSPS---FVADQNFSQPGLGTTEENRKPSLENVVVFGTSVEEAVKEMRFRIEQKTTLTASAGIAPNMMLAKVCSDKNKPNGQYRIFNDKQAIKDFIKDLPIRKVPGIGKVTEKMLKALGIITCTDLYQQRALLSLLFSETSWQNFVHISLGLGSTHVERDG--------ERKSMSTERTFSEISSSEEQYDLCQELCRDLAQDLQKEGLKGKTVTIKLKNVKFEVRTRALTVGSTVSTEEEIFAVAKEILKAEIDLASPEPLRLRLMGVRVSGFLTEEEKKHHQKSITGFLHVSKPGSSSSLGQSDKANPSALATGPQ---RQSFFNQKRAAREHMVQEKHAVCSGFVKSEDATISDSEGKTETLDLENVSQKPEFTCPICFLKESDWDLASFNKHIDKCLSRSPISSE 649

[Close]

BLAST of DNA polymerase kappa vs. Ensembl Xenopus
Match: sec31a (SEC31 homolog A, COPII coat complex component [Source:Xenbase;Acc:XB-GENE-5955093])

HSP 1 Score: 382.489 bits (981), Expect = 4.256e-122
Identity = 242/647 (37.40%), Postives = 355/647 (54.87%), Query Frame = 3

Query:   90 LKVNDNKAGMENLDKKKINETILEASRGSKYYEHEVXXXXXXXXXXXXXXXXYNSLSENDILRGVKKANKLLENISINRNLNQTFVHIDMDAYFAAVEINDNPSLRTKPMAVGSSSMLSTSNYVARKFGVRAGMPGFIAKKLCPDIILIEPNFNKYISISRIFRKIFLDYDINYSACGLDEATLDITEHLKNRISYSDKQRTFSCNVS--------------------CECRIPIQINSKQTKLFKICDE--CGKLIGAQEK----------TFSISSWSAVEELRFRIFARTQLTSSAGMASNGLLAKIVSDINKPNGQYHLSSDPWDINVFIKQLPVGKVPGIGKVSERKLDVLGIVKCEDFYHKRGALYHLFKPCMFSYFMRISLGXXXXXXXXXXXXXXXNGIDRKSMSVERTFPDCNDPILLMEKCKTLCKDLWKELLKKNLLGKCISIKLKLSSFEVRTRAFSNLEATNDLNNITNCACELLQTEINNNQPHKLCLRLLGVRISVL------------------------------SMKLSP--LATLTQLNIKEAFKNQEMKAES-------------TKKEEG-VNHEEQLKEKCSSEVIKDDSIVQCPVCFV---SVNISNINTHLDFCI--SPANSE 1781
            + +NDNKAGME LDK+KIN+ I++A++GS++Y++E+KK ++  +++  L ++ + L++  I +   + ++L   +  NR+L++  VH+DMDA++AAVE+ D+P L+ KPMAVGS+SMLSTSNY+AR+FGVRA MPGFIAKKLCP + ++ PNF+KY ++S   R+I   YD N+    LDEA LDIT+HL  R+++ + +RTF    +                     EC  P+      +    + D+      +G  E+           F  S   AV+E+RFRI  +T LT+SAG+A N +LAK+ SD NKPNGQY + +D   I  FIK LP+ KVPGIGKV+E+ L  LGI+ C D Y +R  L  LF    +  F+ ISLG GS               +RKSMS ERTF + +      + C+ LC+DL ++L K+ L GK ++IKLK   FEVRTRA +     +    I   A E+L+ EI+   P  L LRL+GVR+S                                S K +P  LAT  Q   +++F NQ+  A                K E+  ++  E   E    E +       CP+CF+     ++++ N H+D C+  SP +SE
Sbjct:   20 MGLNDNKAGMEGLDKEKINKIIMDATKGSRFYDNELKKDQQVNQRIEKLMQQKSQLTDQQIKKAQIQVDRLALELERNRDLSRIIVHVDMDAFYAAVEMRDSPELKDKPMAVGSNSMLSTSNYLARRFGVRAAMPGFIAKKLCPTLKIVPPNFDKYRAVSSEVREILAQYDPNFLPMSLDEAYLDITDHLSERLAWPEDKRTFMIRTNNSGGNKPLPDTTRLDSDLEQVECTSPVLFEDSPS---FVADQNFSQPGLGTTEENRKPSLENVVVFGTSVEEAVKEMRFRIEQKTTLTASAGIAPNMMLAKVCSDKNKPNGQYRIFNDKQAIKDFIKDLPIRKVPGIGKVTEKMLKALGIITCTDLYQQRALLSLLFSETSWQNFVHISLGLGSTHVERDG--------ERKSMSTERTFSEISSSEEQYDLCQELCRDLAQDLQKEGLKGKTVTIKLKNVKFEVRTRALTVGSTVSTEEEIFAVAKEILKAEIDLASPEPLRLRLMGVRVSGFLTEEEKKHHQKSITGFLHVSKPGSSSSLGQSDKANPSALATGPQ---RQSFFNQKRAAREHMVQEKHAVCSGFVKSEDATISDSEGKTETLDLENVSQKPEFTCPICFLKESDWDLASFNKHIDKCLSRSPISSE 652

[Close]

BLAST of DNA polymerase kappa vs. Ensembl Mouse
Match: Polk (polymerase (DNA directed), kappa [Source:MGI Symbol;Acc:MGI:1349767])

HSP 1 Score: 367.466 bits (942), Expect = 2.355e-119
Identity = 207/510 (40.59%), Postives = 302/510 (59.22%), Query Frame = 3

Query:   81 LSSLKVNDNKAGMENLDKKKINETILEASRGSKYYEHEVXXXXXXXXXXXXXXXXYNSLSENDILRGVKKANKLLENISINRNLNQTFVHIDMDAYFAAVEINDNPSLRTKPMAVGSSSMLSTSNYVARKFGVRAGMPGFIAKKLCPDIILIEPNFNKYISISRIFRKIFLDYDINYSACGLDEATLDITEHLKNRISYSDKQRTFSCNVSCECRI----------------------------------PIQINSKQTKLFKICDECGKLIGAQEKTFSISSWSAVEELRFRIFARTQLTSSAGMASNGLLAKIVSDINKPNGQYHLSSDPWDINVFIKQLPVGKVPGIGKVSERKLDVLGIVKCEDFYHKRGALYHLFKPCMFSYFMRISLGXXXXXXXXXXXXXXXNGIDRKSMSVERTFPDCNDPILLMEKCKTLCKDLWKELLKKNLLGKCISIKLKLSSFEVRTRAFSNLEATNDLNNITNCACELLQTEINNNQPHKLCLRLL 1508
            L  + +NDNKAGME LDK+KIN+ I+EA++GS++Y +E+KK K+  +++  + ++   ++   + +   + +K    +  NRNLN T VH+DMDA++AAVE+ DNP L+ KP+AVGS SML+TSNY AR+FGVRA MPGFIAK+LCP +I++ PNF+KY ++S+  ++I  +YD N+ A  LDEA L+IT+HL+ R  + + +R +   +    +I                                  P Q+NS+        ++    I      F  S+   V+E+RFRI  +T LT+SAG+A N +LAK+ SD NKPNGQY +      +  FIK LP+ KV GIGKV+E+ L  LGIV C + Y +R  L  LF    + YF+ I+LG GS + +           +RKSMSVERTF + +        C+ LC +L  +L K+ L G+ ++IKLK  +FEV+TRA +   A +    I   A ELL+TE+N   PH L LRL+
Sbjct:   15 LLRMGLNDNKAGMEGLDKEKINKIIMEATKGSRFYGNELKKEKQVNQRIENMMQQKAQITSQQLRKAQLQVDKFAMELERNRNLNNTIVHVDMDAFYAAVEMRDNPELKDKPIAVGSMSMLATSNYHARRFGVRAAMPGFIAKRLCPQLIIVPPNFDKYRAVSKEVKEILAEYDPNFMAMSLDEAYLNITQHLQERQDWPEDKRRYFIKMGNYLKIDTPRQEANELTEYERSISPLLFEDSPPDLQPQGSPFQLNSE--------EQNNPQIAQNSVVFGTSAEEVVKEIRFRIEQKTTLTASAGIAPNTMLAKVCSDKNKPNGQYQILPSRSAVMDFIKDLPIRKVSGIGKVTEKMLMALGIVTCTELYQQRALLSLLFSETSWHYFLHIALGLGSTDLARDG--------ERKSMSVERTFSEISKTEEQYSLCQELCAELAHDLQKEGLKGRTVTIKLKNVNFEVKTRASTVPAAISTAEEIFAIAKELLRTEVNVGSPHPLRLRLM 508

[Close]

BLAST of DNA polymerase kappa vs. Ensembl Mouse
Match: Polk (polymerase (DNA directed), kappa [Source:MGI Symbol;Acc:MGI:1349767])

HSP 1 Score: 375.941 bits (964), Expect = 4.941e-119
Identity = 212/518 (40.93%), Postives = 308/518 (59.46%), Query Frame = 3

Query:   81 LSSLKVNDNKAGMENLDKKKINETILEASRGSKYYEHEVXXXXXXXXXXXXXXXXYNSLSENDILRGVKKANKLLENISINRNLNQTFVHIDMDAYFAAVEINDNPSLRTKPMAVGSSSMLSTSNYVARKFGVRAGMPGFIAKKLCPDIILIEPNFNKYISISRIFRKIFLDYDINYSACGLDEATLDITEHLKNRISYSDKQRTFSCNVSCECRI----------------------------------PIQINSKQTKLFKICDECGKLIGAQEKTFSISSWSAVEELRFRIFARTQLTSSAGMASNGLLAKIVSDINKPNGQYHLSSDPWDINVFIKQLPVGKVPGIGKVSERKLDVLGIVKCEDFYHKRGALYHLFKPCMFSYFMRISLGXXXXXXXXXXXXXXXNGIDRKSMSVERTFPDCNDPILLMEKCKTLCKDLWKELLKKNLLGKCISIKLKLSSFEVRTRAFSNLEATNDLNNITNCACELLQTEINNNQPHKLCLRLLGVRISVLS 1532
            L  + +NDNKAGME LDK+KIN+ I+EA++GS++Y +E+KK K+  +++  + ++   ++   + +   + +K    +  NRNLN T VH+DMDA++AAVE+ DNP L+ KP+AVGS SML+TSNY AR+FGVRA MPGFIAK+LCP +I++ PNF+KY ++S+  ++I  +YD N+ A  LDEA L+IT+HL+ R  + + +R +   +    +I                                  P Q+NS++        +    I      F  S+   V+E+RFRI  +T LT+SAG+A N +LAK+ SD NKPNGQY +      +  FIK LP+ KV GIGKV+E+ L  LGIV C + Y +R  L  LF    + YF+ I+LG GS + +           +RKSMSVERTF + +        C+ LC +L  +L K+ L G+ ++IKLK  +FEV+TRA +   A +    I   A ELL+TE+N   PH L LRL+GVR+S  S
Sbjct:   15 LLRMGLNDNKAGMEGLDKEKINKIIMEATKGSRFYGNELKKEKQVNQRIENMMQQKAQITSQQLRKAQLQVDKFAMELERNRNLNNTIVHVDMDAFYAAVEMRDNPELKDKPIAVGSMSMLATSNYHARRFGVRAAMPGFIAKRLCPQLIIVPPNFDKYRAVSKEVKEILAEYDPNFMAMSLDEAYLNITQHLQERQDWPEDKRRYFIKMGNYLKIDTPRQEANELTEYERSISPLLFEDSPPDLQPQGSPFQLNSEE--------QNNPQIAQNSVVFGTSAEEVVKEIRFRIEQKTTLTASAGIAPNTMLAKVCSDKNKPNGQYQILPSRSAVMDFIKDLPIRKVSGIGKVTEKMLMALGIVTCTELYQQRALLSLLFSETSWHYFLHIALGLGSTDLARDG--------ERKSMSVERTFSEISKTEEQYSLCQELCAELAHDLQKEGLKGRTVTIKLKNVNFEVKTRASTVPAAISTAEEIFAIAKELLRTEVNVGSPHPLRLRLMGVRMSTFS 516

[Close]

BLAST of DNA polymerase kappa vs. Ensembl Mouse
Match: Polk (polymerase (DNA directed), kappa [Source:MGI Symbol;Acc:MGI:1349767])

HSP 1 Score: 346.665 bits (888), Expect = 1.973e-108
Identity = 198/484 (40.91%), Postives = 290/484 (59.92%), Query Frame = 3

Query:   81 LSSLKVNDNKAGMENLDKKKINETILEASRGSKYYEHEVXXXXXXXXXXXXXXXXYNSLSENDILRGVKKANKLLENISINRNLNQTFVHIDMDAYFAAVEINDNPSLRTKPMAVGSSSMLSTSNYVARKFGVRAGMPGFIAKKLCPDIILIEPNFNKYISISRIFRKIFLDYDINYSACGLDEATLDITEHLKNRISYSDKQRTFSCNVSCECRIPIQINSKQTKLFKICDECGKLIGAQEKTFSISSWSAVEELRFRIFARTQLTSSAGMASNGLLAKIVSDINKPNGQYHLSSDPWDINVFIKQLPVGKVPGIGKVSERKLDVLGIVKCEDFYHKRGALYHLFKPCMFSYFMRISLGXXXXXXXXXXXXXXXNGIDRKSMSVERTFPDCNDPILLMEKCKTLCKDLWKELLKKNLLGKCISIKLKLSSFEVRTRAFSNLEATNDLNNITNCACELLQTEINNNQPHKLCLRLLGVRISVLS 1532
            L  + +NDNKAGME LDK+KIN+ I+EA++GS++Y +E+KK K+  +++  + ++   ++   + +   + +K    +  NRNLN T VH+DMDA++AAVE+ DNP L+ KP+AVGS SML+TSNY AR+FGVRA MPGFIAK+LCP +I++ PNF+KY ++S+  ++I  +YD N+ A  LDEA L+IT+HL+ R  + + +R +   +    +I +                         T  +++ S +  LR             G+A N +LAK+ SD NKPNGQY +      +  FIK LP+ KV GIGKV+E+ L  LGIV C + Y +R  L  LF    + YF+ I+LG GS + +           +RKSMSVERTF + +        C+ LC +L  +L K+ L G+ ++IKLK  +FEV+TRA +   A +    I   A ELL+TE+N   PH L LRL+GVR+S  S
Sbjct:   15 LLRMGLNDNKAGMEGLDKEKINKIIMEATKGSRFYGNELKKEKQVNQRIENMMQQKAQITSQQLRKAQLQVDKFAMELERNRNLNNTIVHVDMDAFYAAVEMRDNPELKDKPIAVGSMSMLATSNYHARRFGVRAAMPGFIAKRLCPQLIIVPPNFDKYRAVSKEVKEILAEYDPNFMAMSLDEAYLNITQHLQERQDWPEDKRRYFIKMGNYLKIAMM------------------------TLDLAA-SNLNLLR--------PAKPPGIAPNTMLAKVCSDKNKPNGQYQILPSRSAVMDFIKDLPIRKVSGIGKVTEKMLMALGIVTCTELYQQRALLSLLFSETSWHYFLHIALGLGSTDLARDG--------ERKSMSVERTFSEISKTEEQYSLCQELCAELAHDLQKEGLKGRTVTIKLKNVNFEVKTRASTVPAAISTAEEIFAIAKELLRTEVNVGSPHPLRLRLMGVRMSTFS 457

[Close]

BLAST of DNA polymerase kappa vs. Ensembl Mouse
Match: Polk (polymerase (DNA directed), kappa [Source:MGI Symbol;Acc:MGI:1349767])

HSP 1 Score: 335.495 bits (859), Expect = 1.847e-104
Identity = 194/484 (40.08%), Postives = 279/484 (57.64%), Query Frame = 3

Query:   81 LSSLKVNDNKAGMENLDKKKINETILEASRGSKYYEHEVXXXXXXXXXXXXXXXXYNSLSENDILRGVKKANKLLENISINRNLNQTFVHIDMDAYFAAVEINDNPSLRTKPMAVGSSSMLSTSNYVARKFGVRAGMPGFIAKKLCPDIILIEPNFNKYISISRIFRKIFLDYDINYSACGLDEATLDITEHLKNRISYSDKQRTFSCNVSCECRIPIQINSKQTKLFKICDECGKLIGAQEKTFSISSWSAVEELRFRIFARTQLTSSAGMASNGLLAKIVSDINKPNGQYHLSSDPWDINVFIKQLPVGKVPGIGKVSERKLDVLGIVKCEDFYHKRGALYHLFKPCMFSYFMRISLGXXXXXXXXXXXXXXXNGIDRKSMSVERTFPDCNDPILLMEKCKTLCKDLWKELLKKNLLGKCISIKLKLSSFEVRTRAFSNLEATNDLNNITNCACELLQTEINNNQPHKLCLRLLGVRISVLS 1532
            L  + +NDNKAGME LDK+KIN+ I+EA++GS++Y +E+KK K+  +++  + ++   ++   + +   + +K    +  NRNLN T VH+DMDA++AAVE+ DNP L+ KP+AVGS SML+TSNY AR+FGVRA MPGFIAK+LCP +I++ PNF+KY ++S+  ++I  +YD N+ A  LDEA L+IT+HL+ R  + + +R +   +    +I I  N   T L K+C                                                   SD NKPNGQY +      +  FIK LP+ KV GIGKV+E+ L  LGIV C + Y +R  L  LF    + YF+ I+LG GS + +           +RKSMSVERTF + +        C+ LC +L  +L K+ L G+ ++IKLK  +FEV+TRA +   A +    I   A ELL+TE+N   PH L LRL+GVR+S  S
Sbjct:   15 LLRMGLNDNKAGMEGLDKEKINKIIMEATKGSRFYGNELKKEKQVNQRIENMMQQKAQITSQQLRKAQLQVDKFAMELERNRNLNNTIVHVDMDAFYAAVEMRDNPELKDKPIAVGSMSMLATSNYHARRFGVRAAMPGFIAKRLCPQLIIVPPNFDKYRAVSKEVKEILAEYDPNFMAMSLDEAYLNITQHLQERQDWPEDKRRYFIKMGNYLKIGIAPN---TMLAKVC---------------------------------------------------SDKNKPNGQYQILPSRSAVMDFIKDLPIRKVSGIGKVTEKMLMALGIVTCTELYQQRALLSLLFSETSWHYFLHIALGLGSTDLARDG--------ERKSMSVERTFSEISKTEEQYSLCQELCAELAHDLQKEGLKGRTVTIKLKNVNFEVKTRASTVPAAISTAEEIFAIAKELLRTEVNVGSPHPLRLRLMGVRMSTFS 436

[Close]

BLAST of DNA polymerase kappa vs. Ensembl Mouse
Match: Polk (polymerase (DNA directed), kappa [Source:MGI Symbol;Acc:MGI:1349767])

HSP 1 Score: 326.25 bits (835), Expect = 1.874e-104
Identity = 189/476 (39.71%), Postives = 273/476 (57.35%), Query Frame = 3

Query:   81 LSSLKVNDNKAGMENLDKKKINETILEASRGSKYYEHEVXXXXXXXXXXXXXXXXYNSLSENDILRGVKKANKLLENISINRNLNQTFVHIDMDAYFAAVEINDNPSLRTKPMAVGSSSMLSTSNYVARKFGVRAGMPGFIAKKLCPDIILIEPNFNKYISISRIFRKIFLDYDINYSACGLDEATLDITEHLKNRISYSDKQRTFSCNVSCECRIPIQINSKQTKLFKICDECGKLIGAQEKTFSISSWSAVEELRFRIFARTQLTSSAGMASNGLLAKIVSDINKPNGQYHLSSDPWDINVFIKQLPVGKVPGIGKVSERKLDVLGIVKCEDFYHKRGALYHLFKPCMFSYFMRISLGXXXXXXXXXXXXXXXNGIDRKSMSVERTFPDCNDPILLMEKCKTLCKDLWKELLKKNLLGKCISIKLKLSSFEVRTRAFSNLEATNDLNNITNCACELLQTEINNNQPHKLCLRLL 1508
            L  + +NDNKAGME LDK+KIN+ I+EA++GS++Y +E+KK K+  +++  + ++   ++   + +   + +K    +  NRNLN T VH+DMDA++AAVE+ DNP L+ KP+AVGS SML+TSNY AR+FGVRA MPGFIAK+LCP +I++ PNF+KY ++S+  ++I  +YD N+ A  LDEA L+IT+HL+ R  + + +R +   +    +I I  N   T L K+C                                                   SD NKPNGQY +      +  FIK LP+ KV GIGKV+E+ L  LGIV C + Y +R  L  LF    + YF+ I+LG GS + +           +RKSMSVERTF + +        C+ LC +L  +L K+ L G+ ++IKLK  +FEV+TRA +   A +    I   A ELL+TE+N   PH L LRL+
Sbjct:   15 LLRMGLNDNKAGMEGLDKEKINKIIMEATKGSRFYGNELKKEKQVNQRIENMMQQKAQITSQQLRKAQLQVDKFAMELERNRNLNNTIVHVDMDAFYAAVEMRDNPELKDKPIAVGSMSMLATSNYHARRFGVRAAMPGFIAKRLCPQLIIVPPNFDKYRAVSKEVKEILAEYDPNFMAMSLDEAYLNITQHLQERQDWPEDKRRYFIKMGNYLKIGIAPN---TMLAKVC---------------------------------------------------SDKNKPNGQYQILPSRSAVMDFIKDLPIRKVSGIGKVTEKMLMALGIVTCTELYQQRALLSLLFSETSWHYFLHIALGLGSTDLARDG--------ERKSMSVERTFSEISKTEEQYSLCQELCAELAHDLQKEGLKGRTVTIKLKNVNFEVKTRASTVPAAISTAEEIFAIAKELLRTEVNVGSPHPLRLRLM 428

[Close]

BLAST of DNA polymerase kappa vs. UniProt/SwissProt
Match: sp|Q9QUG2|POLK_MOUSE (DNA polymerase kappa OS=Mus musculus OX=10090 GN=Polk PE=1 SV=1)

HSP 1 Score: 375.941 bits (964), Expect = 3.456e-118
Identity = 212/518 (40.93%), Postives = 308/518 (59.46%), Query Frame = 3

Query:   81 LSSLKVNDNKAGMENLDKKKINETILEASRGSKYYEHEVXXXXXXXXXXXXXXXXYNSLSENDILRGVKKANKLLENISINRNLNQTFVHIDMDAYFAAVEINDNPSLRTKPMAVGSSSMLSTSNYVARKFGVRAGMPGFIAKKLCPDIILIEPNFNKYISISRIFRKIFLDYDINYSACGLDEATLDITEHLKNRISYSDKQRTFSCNVSCECRI----------------------------------PIQINSKQTKLFKICDECGKLIGAQEKTFSISSWSAVEELRFRIFARTQLTSSAGMASNGLLAKIVSDINKPNGQYHLSSDPWDINVFIKQLPVGKVPGIGKVSERKLDVLGIVKCEDFYHKRGALYHLFKPCMFSYFMRISLGXXXXXXXXXXXXXXXNGIDRKSMSVERTFPDCNDPILLMEKCKTLCKDLWKELLKKNLLGKCISIKLKLSSFEVRTRAFSNLEATNDLNNITNCACELLQTEINNNQPHKLCLRLLGVRISVLS 1532
            L  + +NDNKAGME LDK+KIN+ I+EA++GS++Y +E+KK K+  +++  + ++   ++   + +   + +K    +  NRNLN T VH+DMDA++AAVE+ DNP L+ KP+AVGS SML+TSNY AR+FGVRA MPGFIAK+LCP +I++ PNF+KY ++S+  ++I  +YD N+ A  LDEA L+IT+HL+ R  + + +R +   +    +I                                  P Q+NS++        +    I      F  S+   V+E+RFRI  +T LT+SAG+A N +LAK+ SD NKPNGQY +      +  FIK LP+ KV GIGKV+E+ L  LGIV C + Y +R  L  LF    + YF+ I+LG GS + +           +RKSMSVERTF + +        C+ LC +L  +L K+ L G+ ++IKLK  +FEV+TRA +   A +    I   A ELL+TE+N   PH L LRL+GVR+S  S
Sbjct:   15 LLRMGLNDNKAGMEGLDKEKINKIIMEATKGSRFYGNELKKEKQVNQRIENMMQQKAQITSQQLRKAQLQVDKFAMELERNRNLNNTIVHVDMDAFYAAVEMRDNPELKDKPIAVGSMSMLATSNYHARRFGVRAAMPGFIAKRLCPQLIIVPPNFDKYRAVSKEVKEILAEYDPNFMAMSLDEAYLNITQHLQERQDWPEDKRRYFIKMGNYLKIDTPRQEANELTEYERSISPLLFEDSPPDLQPQGSPFQLNSEE--------QNNPQIAQNSVVFGTSAEEVVKEIRFRIEQKTTLTASAGIAPNTMLAKVCSDKNKPNGQYQILPSRSAVMDFIKDLPIRKVSGIGKVTEKMLMALGIVTCTELYQQRALLSLLFSETSWHYFLHIALGLGSTDLARDG--------ERKSMSVERTFSEISKTEEQYSLCQELCAELAHDLQKEGLKGRTVTIKLKNVNFEVKTRASTVPAAISTAEEIFAIAKELLRTEVNVGSPHPLRLRLMGVRMSTFS 516

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BLAST of DNA polymerase kappa vs. UniProt/SwissProt
Match: sp|Q9UBT6|POLK_HUMAN (DNA polymerase kappa OS=Homo sapiens OX=9606 GN=POLK PE=1 SV=1)

HSP 1 Score: 371.318 bits (952), Expect = 2.675e-116
Identity = 246/647 (38.02%), Postives = 360/647 (55.64%), Query Frame = 3

Query:   81 LSSLKVNDNKAGMENLDKKKINETILEASRGSKYYEHEVXXXXXXXXXXXXXXXXYNSLSENDILRGVKKANKLLENISINRNLNQTFVHIDMDAYFAAVEINDNPSLRTKPMAVGSSSMLSTSNYVARKFGVRAGMPGFIAKKLCPDIILIEPNFNKYISISRIFRKIFLDYDINYSACGLDEATLDITEHLKNRISY-SDKQRTF-SCNVSCECRIPIQINSKQTK--------LFK----------------ICDECGKLIGAQEKTFSISSWSAVEELRFRIFARTQLTSSAGMASNGLLAKIVSDINKPNGQYHLSSDPWDINVFIKQLPVGKVPGIGKVSERKLDVLGIVKCEDFYHKRGALYHLFKPCMFSYFMRISLGXXXXXXXXXXXXXXXNGIDRKSMSVERTFPDCNDPILLMEKCKTLCKDLWKELLKKNLLGKCISIKLKLSSFEVRTRAFSNLEATNDLNNITNCACELLQTEINNNQPHKLCLRLLGVRISVL--------------------SMKLSPLATLTQLNIKEAF---------------KNQEMK--AESTKKEEGVNHE--------EQLKEKCS-----SEVIKDDSIVQCPVCFVS---VNISNINTHLDFCI-SPANSE 1781
            L  + +NDNKAGME LDK+KIN+ I+EA++GS++Y +E+KK K+  +++  + ++   ++   + +   + ++    +  +RNL+ T VHIDMDA++AAVE+ DNP L+ KP+AVGS SMLSTSNY AR+FGVRA MPGFIAK+LCP +I++ PNF+KY ++S+  ++I  DYD N+ A  LDEA L+IT+HL+ R ++  DK+R F     S E   P +  +K ++        LF+                  ++    I      F  S+   V+E+RFRI  +T LT+SAG+A N +LAK+ SD NKPNGQY +  +   +  FIK LP+ KV GIGKV+E+ L  LGI+ C + Y +R  L  LF    + YF+ ISLG          +    +G +RKSMSVERTF + N        C+ LC +L ++L K+ L G+ ++IKLK  +FEV+TRA +     +    I   A ELL+TEI+ + PH L LRL+GVRIS                      +  LS      +   K+ F               K  E K   + T K E VN +        + LK+K +     SE   D  I+ CPVCF +   +++  +N H+D C+  P+ SE
Sbjct:   16 LLRMGLNDNKAGMEGLDKEKINKIIMEATKGSRFYGNELKKEKQVNQRIENMMQQKAQITSQQLRKAQLQVDRFAMELEQSRNLSNTIVHIDMDAFYAAVEMRDNPELKDKPIAVGSMSMLSTSNYHARRFGVRAAMPGFIAKRLCPQLIIVPPNFDKYRAVSKEVKEILADYDPNFMAMSLDEAYLNITKHLEERQNWPEDKRRYFIKMGSSVENDNPGKEVNKLSEHERSISPLLFEESPSDVQPPGDPFQVNFEEQNNPQILQNSVVFGTSAQEVVKEIRFRIEQKTTLTASAGIAPNTMLAKVCSDKNKPNGQYQILPNRQAVMDFIKDLPIRKVSGIGKVTEKMLKALGIITCTELYQQRALLSLLFSETSWHYFLHISLG-------LGSTHLTRDG-ERKSMSVERTFSEINKAEEQYSLCQELCSELAQDLQKERLKGRTVTIKLKNVNFEVKTRASTVSSVVSTAEEIFAIAKELLKTEIDADFPHPLRLRLMGVRISSFPNEEDRKHQQRSIIGFLQAGNQALSATECTLEKTDKDKFVKPLEMSHKKSFFDKKRSERKWSHQDTFKCEAVNKQSFQTSQPFQVLKKKMNENLEISENSDDCQILTCPVCFRAQGCISLEALNKHVDECLDGPSISE 654

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BLAST of DNA polymerase kappa vs. UniProt/SwissProt
Match: sp|P34409|POLK_CAEEL (DNA polymerase kappa OS=Caenorhabditis elegans OX=6239 GN=polk-1 PE=3 SV=3)

HSP 1 Score: 301.212 bits (770), Expect = 2.149e-92
Identity = 215/580 (37.07%), Postives = 313/580 (53.97%), Query Frame = 3

Query:   90 LKVNDNKAGMENLDKKKINETILEASRGSKYYEHEVXXXXXXXXXXXXXXXXYNSLSENDILRGVKKANKLLENISI----NRNLNQTFVHIDMDAYFAAVEINDNPSLRTKPMAVGSSSMLSTSNYVARKFGVRAGMPGFIAKKLCPDIILIEPNFNKYISISRIFRKIFLDYDINYSACGLDEATLDITEHLKNRISYSDKQRTFSCNV---SCECRIP-IQINSKQTKLFK----ICDECGK--LIGAQEKTFSISSWSAVEELRFRIFARTQLTSSAGMASNGLLAKIVSDINKPNGQYHLSSDPWDINVFIKQLPVGKVPGIGKVSERKLDVLGIVKCEDFYHKRGALYHLFKPCMFSYFMRISLGXXXXXXXXXXXXXXXNGIDRKSMSVERTFPDCNDPILLMEKCKTLCKDLWKELLKKNLL-GKCISIKLKLSSFEVRTRAFSNLEATNDLNNITNCACELLQTEINNNQPHKLCLRLLGVRISVLSMKLSPLATLTQLNIKEAFKNQEMKAESTKKEEGVNHEEQLKEKCSSE-----VIKDDSIVQCPVCFVSVN--ISNINTHLDFCI 1763
            L  NDNKAGM  LDK+KI + I E +  S Y     K+    E+++L +K +  + +  +     +K+  L+EN+ +    +R+L++  V IDMDAYFAAVE+ DNP+LRT PMAVGSS+MLSTSNY+AR+FGVRAGMPGFI+ KLCP + ++  N+ KY  +SR F +IF++YD +     LDEA +D+T++    ++ + +++TF  +     C C +P    N    +  K    IC +C K   I      F      AV E+RFR+   T LT SAG+ASN +LAKI SD+NKPNGQY L +D   I  F+K LP+ KV GIG+V E +L  + I    D   K+      F P     F+R +LG                   RKS+SVERTF   +D  +L+E+ + +C+ L +++ K  ++ GK +++KLKLSSF+V TR+ +  +    L +I   + ELL+ E          +RLLGVR+S L                  F+  E K   T  E     + Q++    SE      +       CP+C   V   +  +N H+D CI
Sbjct:    2 LTFNDNKAGMNGLDKEKITKVIEENTSAS-YSSFSKKQQSRIEEKVLEIKNRLQTATREE----RQKSEILMENLEMKLESSRDLSRDCVCIDMDAYFAAVEMRDNPALRTVPMAVGSSAMLSTSNYLARRFGVRAGMPGFISNKLCPSLTIVPGNYPKYTKVSRQFSQIFMEYDSDVGMMSLDEAFIDLTDY----VASNTEKKTFKRHRFGGDCPCWLPRFDENENTLEDLKIEESICPKCEKSRKIYYDHVEFGTGREEAVREIRFRVEQLTGLTCSAGIASNFMLAKICSDLNKPNGQYVLENDKNAIMEFLKDLPIRKVGGIGRVCEAQLKAMDIQTVGDMNLKKNLYPLCFTPLSQESFLRTALGLPGRPSESDPR--------RKSISVERTFSPTSDFNILLEEHQEICRMLEEDVRKSGIVGGKTVTLKLKLSSFDVLTRSLTPSDVVKSLEDIQKFSLELLEKEKGKE------IRLLGVRLSQL-----------------IFEEDEKKRSKTITEFWNEKKLQIQNLQGSENVDDDDVIMMDTRPCPICGTDVENRLDVMNCHVDECI 541

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BLAST of DNA polymerase kappa vs. UniProt/SwissProt
Match: sp|Q6JDV7|POLK_ARATH (DNA polymerase kappa OS=Arabidopsis thaliana OX=3702 GN=POLK PE=1 SV=1)

HSP 1 Score: 300.827 bits (769), Expect = 1.773e-91
Identity = 184/484 (38.02%), Postives = 270/484 (55.79%), Query Frame = 3

Query:   75 WELSSLKVNDNKAGMENLDKKKINETILEASRGSKYYEHEVXXXXXXXXXXXXXXXXYNSLSENDILRGVKKANKLLENISINRNLNQTFVHIDMDAYFAAVEINDNPSLRTKPMAVGSSSMLSTSNYVARKFGVRAGMPGFIAKKLCPDIILIEPNFNKYISISRIFRKIFLDYDINYSACGLDEATLDITEHLKNRISYSDKQRTFSCNVSCECRIPIQINSKQTKLFKICDECGKLIGAQEKTFSISSWSAVEELRFRIFARTQLTSSAGMASNGLLAKIVSDINKPNGQYHLSSDPWDINVFIKQLPVGKVPGIGKVSERKL-DVLGIVKCEDFYHKRGALYHLFKPCMFSYFMRISLGXXXXXXXXXXXXXXXNGIDRKSMSVERTFPDCNDPILLMEKCKTLCKDLWKELLKKNLLGKCISIKLKLSSFEVRTRAFSNLEATNDLNNITNCACELLQTEINNNQPHKLCLRLLGVRIS 1523
            WE  +    + KAGME +DK+K+   + E S+GSKY+++E +K    ++++  ++++   LS  D+    K  +K +  +   R+L++ ++H+DMDA++AAVE   +PS++ KPMAVG  SM+ST+NY ARKFGVRA MPGFIA+KLCPD+I +  +F KY   S + RK+F +YD ++ A  LDEA LDITE                                      +C E G           +S     EELR  +++ T LT SAG+A+N LLAK+ SDINKPNGQ+ L +D   +  F+  LPV K+ GIGKV+E  L D LGI  CE+   K   LY LF      +F+ + LG G     +V S        RKS+S ERTF    D  LL  K   L + L  ++ K+ L  + +++KLK +SFE+R+RA S    T   ++I   A +LL+ E+       + +RL+G+R+S
Sbjct:   16 WESYNTVFTNAKAGMEGVDKEKVQRVVYEMSKGSKYFQNEERKEALMKQKIEHMRDRCAKLSSLDLSNYQKVVDKRILELEATRDLSRIWLHVDMDAFYAAVETLSDPSIKGKPMAVGGLSMISTANYEARKFGVRAAMPGFIARKLCPDLIFVPVDFTKYTHYSDLTRKVFRNYDPHFIAGSLDEAYLDITE--------------------------------------VCRERG-----------LSGGEIAEELRSSVYSETGLTCSAGVAANRLLAKVCSDINKPNGQFVLQNDRSTVMTFVSFLPVRKIGGIGKVTEHILKDALGIKTCEEMVQKGSLLYALFSQSSADFFLSVGLGLGGTNTPQVRS--------RKSISSERTFAATGDERLLYSKLDELAEMLSHDMKKEGLTARTLTLKLKTASFEIRSRAVSLQRYTCSSDDILKHATKLLKAEL------PVSVRLIGLRMS 436

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BLAST of DNA polymerase kappa vs. UniProt/SwissProt
Match: sp|O74944|POLK_SCHPO (DNA polymerase kappa OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=mug40 PE=1 SV=3)

HSP 1 Score: 219.935 bits (559), Expect = 2.634e-62
Identity = 176/588 (29.93%), Postives = 280/588 (47.62%), Query Frame = 3

Query:  108 KAGMENLDKKKINETILEASRGSKYYEHEVX---------XXXXXXXXXXXXXXXYNSLSENDILRGVKKANKLLENISINRNLNQTFVHIDMDAYFAAVEINDNPSLRTKPMAVGSSSMLSTSNYVARKFGVRAGMPGFIAKKLCPDIILIEPNFNKYISISRIFRKIFLDYDINYSACGLDEATLDITEHLKNRISYSDKQRTFSCNVSCECRIPIQINSKQTKLFKICDECGKLIGAQEKTFSISSWS-AVEELRFRIFARTQLTSSAGMASNGLLAKIVSDINKPNGQYHLSSDPWDINVFIKQLPVGKVPGIGKVSERKLDVLGIVKCEDFYHKRGALYHLFKPCMFSYFMRISLGXXXXXXXXXXXXXXXNGIDRKSMSVERTF-PDCNDPILLMEKCKTLCKDLWKELLKKNLLGKCISIKLKLSSFEVRTRAFSNLEATNDLNNITNCACELLQTEINNNQPHKLCLRLLGVRISVLSMKLSPLATLTQLNIKEAFKNQEMKAESTKKEEGVNHEEQLKEKCSSEVIKDDSIVQCPVCFVSVNISN----INTHLDFC--ISPANSEQPSTSTYVPTLKR 1820
            K+G EN+++KKINE I EAS+GSK++E E K         +  + E +    K +++   + +     +  +  +E+    R+L Q  VH+D DA++A++E   NP L++ PMAVG S +L T+NYVARKFGVR+ MP FIA+K+CPD+++I  N ++Y   S+  + +   YD N     +DE  +++T HL+                                              QE  F++ + +  VE++R ++   T +T S G+A+N LLAKI S+  KPN Q+ +  D   I+ F+  LPV +V GIG+V E++L  L I  C D       L ++F P  F   +R S G G+    E           RK++  E TF  + + P ++  K + L +++ + L K+ L+   I+IK K S F+V T+  S  +  +  +++   A +LL+      Q + + +RLLGVR + L  K   LA                               QLK        +  + V CPVC    NI N    +N H+D C  +    S   +  T  PT+K+
Sbjct:   45 KSGQENVNQKKINEIIYEASKGSKFFEAEQKRDRELRLRIEKVQVEVEKYQSKLRFDKAFQREWTIRQESVDTTVEDFRAKRDLTQIIVHVDCDAFYASIEELKNPKLKSLPMAVGKS-VLCTANYVARKFGVRSAMPEFIARKICPDLVVIPLNLSEYAIKSKEIQNVLAQYDSNLCPASIDEFYMNLTSHLR---------------------------------------------LQELAFTVENITMVVEKIRKQVHEETGVTVSCGIAANKLLAKIASNKRKPNNQFFIPFDEIGISKFMNDLPVREVSGIGRVLEQQLLGLEIKTCGDIQRNLVILSYIFLPKSFQNLLRCSYGFGTTILDEYGES------KRKTIGSEATFSSNLSSPSIIEYKLRLLVQNVSENLQKRGLVTNSIAIKYKTSEFQVHTKQKSIGQFIHSESDLLKPALQLLR------QSYPMTIRLLGVRATKLVSKSRCLAM------------------------------QLK-------FQSQNTVPCPVC--QKNIENELGILNQHVDLCLNVETVKSLINTDHTANPTIKK 535

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BLAST of DNA polymerase kappa vs. TrEMBL
Match: A0A2C9JXS0 (UmuC domain-containing protein OS=Biomphalaria glabrata OX=6526 GN=106072262 PE=3 SV=1)

HSP 1 Score: 402.905 bits (1034), Expect = 5.351e-127
Identity = 238/543 (43.83%), Postives = 335/543 (61.69%), Query Frame = 3

Query:   81 LSSLKVNDNKAGMENLDKKKINETILEASRGSKYYEHEVXXXXXXXXXXXXXXXXYNSLSENDILRGVKKANKLLENISINRNLNQTFVHIDMDAYFAAVEINDNPSLRTKPMAVGSSSMLSTSNYVARKFGVRAGMPGFIAKKLCPDIILIEPNFNKYISISRIFRKIFLDYDINYSACGLDEATLDITEHLKNRISYSDKQRTF------------------SCNVSCECRIPIQINSKQTK----------------------LFKICDECG-KLIGAQEKTFSISSWSAVEELRFRIFARTQLTSSAGMASNGLLAKIVSDINKPNGQYHLSSDPWDINVFIKQLPVGKVPGIGKVSERKLDVLGIVKCEDFYHKRGALYHLFKPCMFSYFMRISLGXXXXXXXXXXXXXXXNGIDRKSMSVERTFPDCNDPILLMEKCKTLCKDLWKELLKKNLLGKCISIKLKLSSFEVRTRAFSNLEATNDLNNITNCACELLQTEINNNQPHKLCLRLLGVRISVLSMKLSPLATLTQLNIKEAF 1586
            +S++ +NDNKAGME L+K+KIN+ I EAS+GSK++E+E KK ++  +++L  +   +SLS   +  G+K+A++L+E +   ++L+ T VH+DMDA++AAVE+ D+P L+ KPMAVG  SMLSTSNY+ARK+GVRA MPGFIA KLCP+++L+EPNF KY ++S+  R+IF  YD N+S   LDEA LD+TEHL  R   S+  R F                  +CN++   R P  IN ++ K                      L K C  C  KL     K +  +   AV E+R RI  RT LT+SAG+A N +LAK+ SD NKPNGQ+ +  D  +I  F+K LP+ K+ GIGKV+E+ L  L I  C D Y +R  LYH F    F YFM+I+LG GS    + E        +RKS+S ERTF + +DP  L EKC  LC+ L K+L ++ L+GK +S+K+K  SFE++TR+ +    TND   I N A +LL+ EI++ +   L LRL+GVR+S    KL P A+  Q++I   F
Sbjct:   12 ISTMAINDNKAGMEGLNKEKINQIIFEASKGSKFFENEQKKEEQLNQKILEQQILISSLSSAMLFHGLKEADELIEKLKACQDLSHTIVHVDMDAFYAAVEMRDDPRLKDKPMAVGGMSMLSTSNYIARKYGVRAAMPGFIALKLCPNLVLVEPNFTKYTAVSQEIREIFAQYDPNFSPMSLDEAYLDLTEHLIYRRGSSNLCRIFLLRLKTDNSSIVVNDLECTCNLNAVLR-PSVINLEELKINSVSSENLQEYLNSLDFSNFNLPKDCQVCNKKLPPFSLKLYDTTVEDAVLEMRNRIEQRTFLTASAGIAPNTMLAKVCSDRNKPNGQFQIHPDVQEIEEFMKNLPIRKISGIGKVTEKLLGSLNISLCSDLYKQRALLYHAFSSLTFQYFMKITLGMGSTSLEKDE--------ERKSLSTERTFAEISDPAQLYEKCAELCQHLAKDLNEEQLMGKTVSLKIKTISFEIKTRSHTLQCYTNDEKIIFNAAKQLLKVEIDSVKQSLLRLRLMGVRMS----KLVPQAS-NQVSIVSLF 540

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BLAST of DNA polymerase kappa vs. TrEMBL
Match: R7T7Z3 (UmuC domain-containing protein OS=Capitella teleta OX=283909 GN=CAPTEDRAFT_151315 PE=3 SV=1)

HSP 1 Score: 399.438 bits (1025), Expect = 8.692e-127
Identity = 238/592 (40.20%), Postives = 338/592 (57.09%), Query Frame = 3

Query:   81 LSSLKVNDNKAGMENLDKKKINETILEASRGSKYYEHEVXXXXXXXXXXXXXXXXYNSLSENDILRGVKKANKLLENISINRNLNQTFVHIDMDAYFAAVEINDNPSLRTKPMAVGSSSMLSTSNYVARKFGVRAGMPGFIAKKLCPDIILIEPNFNKYISISRIFRKIFLDYDINYSACGLDEATLDITEHLKNRISYSDKQRTFSCNVSCECRIPIQINSKQTKLFKICDECGKLIGAQEKTFSISSWSAVEELRFRIFARTQLTSSAGMASNGLLAKIVSDINKPNGQYHLSSDPWDINVFIKQLPVGKVPGIGKVSERKLDVLGIVKCEDFYHKRGALYHLFKPCMFSYFMRISLGXXXXXXXXXXXXXXXNGIDRKSMSVERTFPDCNDPILLMEKCKTLCKDLWKELLKKNLLGKCISIKLKLSSFEVRTRAFSNLEATNDLNNITNCACELLQTEINNNQPHKLCLRLLGVRISVLSMKLSPLATLTQLNIKEAFKNQE--------------------MKAESTKKEE---GVNHEEQLKEKCSSEVIKDDSIVQCPVCFVS----VNISNINTHLDFCISPAN 1775
            L  + +NDNKAGM NLDK++IN+ I E S+GSKYYE+E +K ++ + ++    ++  S    +I +   +A+ +L  I   R+ ++T VHIDMDA++AAVE+ DNPSL+  PMAVG S+MLSTSNY AR+FGVRA MPGFIAKKLCPD++++  NF+KY  +S+  ++I L YD N     LDEA LDIT+HL  R ++  +Q+TF                             +    +++ F + +   V+E+RFRI  +TQLT+SAG+A N +LAK+ SD NKPNGQY +  +   +  F+K LPV KV GIG+VS   L  +G+V C D + KRG L  L+    F+YF+R+S G        V S     G DRKSMS ERTF + N P  L  KC  LC+ L ++L K+NL GK I++K+K   + VRT+A S L AT D+  + + A +LL+TEI    P  L LRL+GVR+S LS   +  ++ TQ+ I +  K                       M+ +    +E   G N         S+E  KD++   CPVC       V++   N H+D C+   N
Sbjct:   35 LDRMALNDNKAGMGNLDKERINKVIYEMSKGSKYYENEQRKEEQVKAKIAAQHKQIQSFDAREIEKSELQADAMLAAIEEMRDFSRTIVHIDMDAFYAAVEMRDNPSLKNIPMAVGGSAMLSTSNYEARRFGVRAAMPGFIAKKLCPDLVIVPTNFDKYRQVSKDVKEILLQYDPNMCPMSLDEAYLDITQHLAERKNFDAEQKTF-----------------------------RTADGEQRMFGVDAEDVVQEIRFRIEVKTQLTASAGIAPNMMLAKVCSDFNKPNGQYLIPFNRQAVMDFVKDLPVRKVCGIGRVSCSMLGAMGVVTCSDLFRKRGLLLKLYSAISFNYFLRVSAG--------VGSTSVQRGDDRKSMSTERTFAEINRPAELFAKCYELCEALVEDLKKENLKGKTITLKIKTIKYIVRTKAHSLLNATQDVQLLYSTARDLLRTEIRLCSPEPLRLRLMGVRMSNLSP--ASKSSDTQITIHQMLKKSRGEQKLPFGAVVSGADRFLSFMEQKDPYVDEDLPGANAFPDEVPHTSTE--KDNTEFICPVCDEHPEDCVDLRTFNEHIDLCLFHTN 585

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BLAST of DNA polymerase kappa vs. TrEMBL
Match: A0A433T4X4 (UmuC domain-containing protein (Fragment) OS=Elysia chlorotica OX=188477 GN=EGW08_015654 PE=3 SV=1)

HSP 1 Score: 399.053 bits (1024), Expect = 3.917e-126
Identity = 228/552 (41.30%), Postives = 331/552 (59.96%), Query Frame = 3

Query:   81 LSSLKVNDNKAGMENLDKKKINETILEASRGSKYYEHEVXXXXXXXXXXXXXXXXYNSLSENDILRGVKKANKLLENISINRNLNQTFVHIDMDAYFAAVEINDNPSLRTKPMAVGSSSMLSTSNYVARKFGVRAGMPGFIAKKLCPDIILIEPNFNKYISISRIFRKIFLDYDINYSACGLDEATLDITEHLKNRISYSDKQRTF-------SCNVS------CECRI----------------------PIQ--INSKQT-KLFKICDECGKLIGAQE-KTFSISSWSAVEELRFRIFARTQLTSSAGMASNGLLAKIVSDINKPNGQYHLSSDPWDINVFIKQLPVGKVPGIGKVSERKLDVLGIVKCEDFYHKRGALYHLFKPCMFSYFMRISLGXXXXXXXXXXXXXXXNGIDRKSMSVERTFPDCNDPILLMEKCKTLCKDLWKELLKKNLLGKCISIKLKLSSFEVRTRAFSNLEATNDLNNITNCACELLQTEINNNQPHKLCLRLLGVRISVLSMKLSPLATLTQLNIKEAFKNQEMKAESTK 1619
            +S + +NDNKAGME LDK++IN+ I EAS+ SK++E+E KK ++ E ++   + K   +++  +    ++A+K+L  +   RNL+ T VH+DMDA++AAVE+ D+PSL+ KPMAVG   MLSTSNY+AR+FGVRA MPGFI  KLCPD++L++PNF+KY ++S+  R++   YD N+    LDEA LD T+HLKNR       R F        C+ +      C C +                       +Q  +NS+ + + F +C EC K+      K F  S   AV ELR RI  +T LT+SAG+A N +LAK+ SD NKPNGQY +  D  +I  F+  LP+ K+ GIGKV+E+ L  +G+V C D +  R  ++HLF    F +FMRIS G GS               +RKS+S ERTF + +DP LL++KC+ LCK+L +++  +  LGK +++K+K   FEVRTR+F+  + TND   +   A  LLQTEI +  P  L LRL+GVR+S L          +Q+++ E FK  + K +  +
Sbjct:   25 ISRMALNDNKAGMEGLDKERINQIIFEASKDSKFFENEKKKEEQLELRIQEQQSKILKITQAQLRGAEREADKVLTLLENERNLSHTIVHVDMDAFYAAVEMRDDPSLQNKPMAVGGLGMLSTSNYLARRFGVRAAMPGFIGLKLCPDLVLVQPNFDKYTAVSKEIRQVLAQYDPNFCPMSLDEAYLDFTDHLKNRCESLPLSRMFVLQEKNTECDKTYGNKDVCLCDLNSVLRPALLCSSEFRDHGASDETLQAFLNSESSFRGFDVCSECNKIFPRYTCKVFGCSVEDAVLELRNRIEEKTHLTASAGIAPNTMLAKVCSDKNKPNGQYRIKPDKAEIMSFVLDLPIRKISGIGKVTEKLLGSIGVVTCRDLFTHRAMIFHLFSSTSFHHFMRISAGIGSTCVERDG--------ERKSISTERTFSEISDPKLLLQKCRELCKNLSEDMKDEKTLGKTVTLKIKTVEFEVRTRSFTLPDFTNDEATLLKAAQMLLQTEITSELPRPLRLRLMGVRMSKLCSDQD-----SQVSVAEMFKKMDKKYQGDQ 563

[Close]

BLAST of DNA polymerase kappa vs. TrEMBL
Match: V4BHH4 (UmuC domain-containing protein OS=Lottia gigantea OX=225164 GN=LOTGIDRAFT_126473 PE=3 SV=1)

HSP 1 Score: 390.193 bits (1001), Expect = 4.215e-125
Identity = 230/490 (46.94%), Postives = 311/490 (63.47%), Query Frame = 3

Query:   69 PEWELSSLKVNDNKAGMENLDKKKINETILEASRGSKYYEHEVXXXXXXXXXXXXXXXXYNSLSENDILRGVKKANKLLENISINRNLNQTFVHIDMDAYFAAVEINDNPSLRTKPMAVGSSSMLSTSNYVARKFGVRAGMPGFIAKKLCPDIILIEPNFNKYISISRIFRKIFLDYDINYSACGLDEATLDITEHLKNRISYSDKQRTF---SCNVSCE--CRIPIQI-NSKQT--KLFKICDECGKLIGAQE-KTFSISSWSAVEELRFRIFARTQLTSSAGMASNGLLAKIVSDINKPNGQYHLSSDPWDINVFIKQLPVGKVPGIGKVSERKLDVLGIVKCEDFYHKRGALYHLFKPCMFSYFMRISLGXXXXXXXXXXXXXXXNGIDRKSMSVERTFPDCNDPILLMEKCKTLCKDLWKELLKKNLLGKCISIKLKLSSFEVRTRAFSNLEATNDLNNITNCACELLQTEINNNQPHKLCLRLLG 1511
            P   ++ +++ND+KAGME LDK KIN+ I EAS+GSKY+E+E KK ++ ++++   K +   ++   +  G+K+A+ LL  +    +L++  VH+DMDA++AAVE+ DNPSLR KPMAVG   MLSTSNY+ARKFGVRA MPGFI  KLCP++IL++ N  KY ++S+  R I +DYD NY    LDEA LD T+H+K R + SDK R+F   +C+V  E  C    Q  NS Q   ++  IC  C K     E K F      AV E+R RI  RT+LT+SAG+A N +LAK+ SD NKPNGQY + +    I  FI  LP+ K+ GIGK+SE+ L+ LG+VKC D Y  R  LYHL+    F YFMRI LG GS               +RKSMS ERTF D ++P  L +KC  L + L K+L ++ L GK +++K+K S+FEV+TRA +  +   D   I N   ELL+ EI N QP  L LRL+G
Sbjct:   19 PSSLMTRMELNDHKAGMEGLDKAKINQIIYEASKGSKYFENEKKKEEQVKERIEEQKRRMEKITAEQLQHGLKQADGLLSELESLFDLSRYIVHVDMDAFYAAVEMRDNPSLRYKPMAVGGMGMLSTSNYLARKFGVRAAMPGFIGLKLCPNLILVKSNQEKYSAVSKEIRAIMVDYDPNYCPLSLDEAYLDFTDHMKTRETSSDKDRSFLVKNCSVDDESKCMYSTQFSNSSQIEKEMLLICPVCNKPYPPYEVKLFDKDIEDAVNEMRCRIEQRTRLTASAGIAPNMMLAKVCSDKNKPNGQYRIQACRDSIKEFIDDLPIRKISGIGKISEQMLNALGVVKCRDLYQHRSLLYHLYSDISFHYFMRICLGLGSTTVERDS--------ERKSMSTERTFRDMSNPSDLYDKCLELSESLSKDLNEEGLKGKTVTLKIKTSTFEVKTRAQTIPDYIWDQETIYNTCKELLRIEIANAQPKPLTLRLMG 500

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BLAST of DNA polymerase kappa vs. TrEMBL
Match: A0A218VA30 (DNA polymerase kappa OS=Lonchura striata domestica OX=299123 GN=POLK PE=3 SV=1)

HSP 1 Score: 394.815 bits (1013), Expect = 8.688e-123
Identity = 250/674 (37.09%), Postives = 370/674 (54.90%), Query Frame = 3

Query:   33 FDHYNLISNLNMPEWELSSLKVNDNKAGMENLDKKKINETILEASRGSKYYEHEVXXXXXXXXXXXXXXXXYNSLSENDILRGVKKANKLLENISINRNLNQTFVHIDMDAYFAAVEINDNPSLRTKPMAVGSSSMLSTSNYVARKFGVRAGMPGFIAKKLCPDIILIEPNFNKYISISRIFRKIFLDYDINYSACGLDEATLDITEHLKNRISYSDKQRTFSCNVSCECRIP---IQINSK---------------QTKLFKICDECGKLIGAQEKTFSISSWSAVEELRFRIFARTQLTSSAGMASNGLLAKIVSDINKPNGQYHLSSDPWDINVFIKQLPVGKVPGIGKVSERKLDVLGIVKCEDFYHKRGALYHLFKPCMFSYFMRISLGXXXXXXXXXXXXXXXNGIDRKSMSVERTFPDCNDPILLMEKCKTLCKDLWKELLKKNLLGKCISIKLKLSSFEVRTRAFSNLEATNDLNNITNCACELLQTEINNNQPHKLCLRLLGVRIS-------------VLSMKLSPLATLTQLNIKEAFKNQEMKAESTKKEEGVNHEEQL------------KEKCSSEVIKDD----------------------SIVQCPVCF---VSVNISNINTHLDFC-----------ISPANSEQPSTSTYVPTLK 1817
             D    +SN +  +  L  + +NDNKAGM+ LDK+KIN+ I+EA++GSK+YE+E+KK ++  +++  + +    ++   +L+   + +KL+  +  NR+L+ T VHIDMDA++AAVE+ DNP L+ KP+AVGS SMLSTSNY AR+FGVRA MPGFIAK+LCP + ++  NF KY  +S+  R+I  +YD N+   GLDEA L+ITEHL+ R+++ + +R F  N      I    I +++K                T L     E   L       F  S+  AV+E+RFRI  +TQLT+SAG+A N +LAK+ SD NKPNGQY +S +   +  F+K LP+ KVPGIGKV+E+ L  LGIV C + Y +R  L  +F    +  F+ ISLG GS    +          +RKSMS ERTF + N        C+ LC+DL +EL K+ L GK +++KLK  +FEV+TRA + L + +    I   A +LL TEI++  PH L +RL+GVR+S              ++  L     +  L ++    NQE   ++++   G   +++              E  S ++ +DD                       I  CPVCF    S N+  +N H+D C           IS  +S + +TS ++P  K
Sbjct:    1 MDDMKKVSNSSCNDGLLLRMGLNDNKAGMQGLDKEKINKIIMEATKGSKFYENELKKDQQVNQRIEKMMQLKEKITAQQLLKAQMQVDKLVIELEQNRDLSSTIVHIDMDAFYAAVEMRDNPELKEKPIAVGSMSMLSTSNYHARRFGVRAAMPGFIAKRLCPHLTIVPLNFKKYGKVSKEVREILAEYDPNFMPVGLDEAYLNITEHLEERLNWPEDRRRFFFNTESTTGIDKDCINMSAKFNEGEVSSSPILFEDNTSLMDDSLEQRDLSVENSVVFGTSAEEAVKEIRFRIEQKTQLTASAGIAPNTMLAKMCSDHNKPNGQYRISPERLAVLDFLKDLPIRKVPGIGKVTEKMLKALGIVTCSELYQQRALLSLIFSEVSWRNFLDISLGLGSTHLEKDG--------ERKSMSTERTFSEINTAEDQYSLCRELCRDLAQELQKEGLKGKTVTLKLKNVNFEVKTRASTVLSSVSTEEEIFTVAKDLLGTEIDSVAPHPLRIRLMGVRVSGFLTEEEKKYQQKSITSFLKSGKEIGILRLQPEKANQEYFTKNSEAHRGSFFDQKRAARQLNSENISPNESRSKQLFQDDKSPANFMEETEKVTDSQNSDVCKIFTCPVCFEKQSSNNLEELNRHIDECLSGMCVKDTVEISKNDSSRENTSNFLPQFK 666

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BLAST of DNA polymerase kappa vs. Ensembl Cavefish
Match: polk (DNA polymerase kappa [Source:NCBI gene;Acc:103046822])

HSP 1 Score: 374.785 bits (961), Expect = 8.099e-118
Identity = 213/490 (43.47%), Postives = 296/490 (60.41%), Query Frame = 3

Query:   81 LSSLKVNDNKAGMENLDKKKINETILEASRGSKYYEHEVXXXXXXXXXXXXXXXXYNSLSENDILRGVKKANKLLENISINRNLNQTFVHIDMDAYFAAVEINDNPSLRTKPMAVGSSSMLSTSNYVARKFGVRAGMPGFIAKKLCPDIILIEPNFNKYISISRIFRKIFLDYDINYSACGLDEATLDITEHLKNRISYSDKQRTFSCNVS-CECRIPIQINSKQTK-----LFKICDECGKLIG---AQEKTFSISSWSAVEELRFRIFARTQLTSSAGMASNGLLAKIVSDINKPNGQYHLSSDPWDINVFIKQLPVGKVPGIGKVSERKLDVLGIVKCEDFYHKRGALYHLFKPCMFSYFMRISLGXXXXXXXXXXXXXXXNGIDRKSMSVERTFPDCNDPILLMEKCKTLCKDLWKELLKKNLLGKCISIKLKLSSFEVRTRAFSNLEATNDLNNITNCACELLQTEINNNQPHKLCLRLLGVRIS 1523
            LS + +NDNKAGME LD+ KIN+ ILE S+GS++YE+E+KK  +  +++  + ++   L+E  I     +  KL   +   RNL++  VH+DMDA++AAVE+ D P L+ KPMAVGS SMLSTSNY AR++GVRA MPGFIAKKLCP+++++  NF KY ++S   R++F DYD ++    LDEA LDIT+HL+ R  + +  RT+  N    E   P      +T      LF+              + + F  S   AV E+RFRI  +T LT+SAG+A N +LAK+ SD NKPNGQY +  +   +  FI+ LPV KV GIGKV+E+ L  LGIV C     +   L  LF    + +F++ISLG GS               +RKSMS ERTF + +D       C+ LC+DL K+L K+ L GK +++KLK   FEV+T+AF+   A      I   A +LL+ EI+N  P  L LRL+GVR+S
Sbjct:   19 LSRMALNDNKAGMEGLDRDKINKIILETSKGSRFYENELKKEHQVNQRIEKILQQKAKLTEQQIQNAQIEVEKLSAELERGRNLSRVIVHVDMDAFYAAVEMRDCPELKDKPMAVGSMSMLSTSNYYARRYGVRAAMPGFIAKKLCPNLVIVPLNFAKYRAVSEQVREVFADYDPHFLPMSLDEAYLDITDHLEQRQHWPESMRTYPINEGNSEGDKPSTETEAETDTLSPVLFEDSPTASPTFPVPRGKGEVFGTSPEEAVREMRFRIEQKTSLTASAGIAPNMMLAKVCSDKNKPNGQYRIPPERQAVMDFIQDLPVRKVSGIGKVTEKMLAALGIVSCAQLAQQMAMLSLLFSDTSWHHFIQISLGLGSTHIERDS--------ERKSMSTERTFAEMSDAEEQYSLCRDLCQDLAKDLQKEGLKGKTVTLKLKNVKFEVKTKAFTLQCAVCTEEEIFTAAKDLLKAEIDNVSPQPLRLRLMGVRVS 500

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BLAST of DNA polymerase kappa vs. Ensembl Cavefish
Match: poli (DNA polymerase iota [Source:NCBI gene;Acc:103044286])

HSP 1 Score: 95.5153 bits (236), Expect = 4.822e-20
Identity = 78/256 (30.47%), Postives = 123/256 (48.05%), Query Frame = 3

Query:  333 NQTFVHIDMDAYFAAVEINDNPSLRTKPMAVGSSSMLSTSNYVARKFGVRAGMPGFIAKKLCPDIILIE-PNFNKYISISRIFRKIFLDYDINYSACGLDEATLDITEHLKNRI---SYSDKQRTFSCNVSCECRIPIQINSKQTKLFKICDECGKLIGAQEKTFSISSWSAVEELRFRIFARTQLTSSAGMASNGLLAKIVSDINKPNGQYHLSSDPWDINVFIKQLPVG-KVPGIGKVSERKLDVLGIVKCEDF 1085
             +  +H D+D ++A VE+  NP+LR+KP+ V    ++ T NYVAR+  V   M    A + CPD++L++  +   Y  IS    ++ + +       G DE  +D++E ++ R+   S SD   +F  +V             +    ++ D     +G+          +   ELR  + +R  LTS AG+A++ LLAK+VS   KPN Q  L   P      +  L    KVPGIG  +  KL VLG+V   D 
Sbjct:   43 QRVILHFDLDCFYAQVEMIRNPALRSKPLGVQQKYIIVTCNYVARERSVTKLMGVKEALEKCPDLVLVKGEDLTHYRDISYKVTELLMSFCPLVERLGFDENFVDVSEMVETRMKDTSISD--LSFVGHV----------YGHEASSVEVGDHSRLAVGS----------AIAAELREALRSRLGLTSCAGVATSKLLAKLVSGAFKPNQQTTLL--PQSSAELMNSLSGPCKVPGIGYRTVEKLKVLGVVSVRDL 274

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BLAST of DNA polymerase kappa vs. Ensembl Cavefish
Match: poli (DNA polymerase iota [Source:NCBI gene;Acc:103044286])

HSP 1 Score: 95.5153 bits (236), Expect = 5.194e-20
Identity = 78/256 (30.47%), Postives = 123/256 (48.05%), Query Frame = 3

Query:  333 NQTFVHIDMDAYFAAVEINDNPSLRTKPMAVGSSSMLSTSNYVARKFGVRAGMPGFIAKKLCPDIILIE-PNFNKYISISRIFRKIFLDYDINYSACGLDEATLDITEHLKNRI---SYSDKQRTFSCNVSCECRIPIQINSKQTKLFKICDECGKLIGAQEKTFSISSWSAVEELRFRIFARTQLTSSAGMASNGLLAKIVSDINKPNGQYHLSSDPWDINVFIKQLPVG-KVPGIGKVSERKLDVLGIVKCEDF 1085
             +  +H D+D ++A VE+  NP+LR+KP+ V    ++ T NYVAR+  V   M    A + CPD++L++  +   Y  IS    ++ + +       G DE  +D++E ++ R+   S SD   +F  +V             +    ++ D     +G+          +   ELR  + +R  LTS AG+A++ LLAK+VS   KPN Q  L   P      +  L    KVPGIG  +  KL VLG+V   D 
Sbjct:   29 QRVILHFDLDCFYAQVEMIRNPALRSKPLGVQQKYIIVTCNYVARERSVTKLMGVKEALEKCPDLVLVKGEDLTHYRDISYKVTELLMSFCPLVERLGFDENFVDVSEMVETRMKDTSISD--LSFVGHV----------YGHEASSVEVGDHSRLAVGS----------AIAAELREALRSRLGLTSCAGVATSKLLAKLVSGAFKPNQQTTLL--PQSSAELMNSLSGPCKVPGIGYRTVEKLKVLGVVSVRDL 260

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BLAST of DNA polymerase kappa vs. Ensembl Cavefish
Match: rev1 (REV1 DNA directed polymerase [Source:NCBI gene;Acc:103044976])

HSP 1 Score: 75.8702 bits (185), Expect = 8.209e-14
Identity = 65/237 (27.43%), Postives = 95/237 (40.08%), Query Frame = 3

Query:  375 AVEINDNPSLRTKPMAVGSSSMLSTSNYVARKFGVRAGMPGFIAKKLCPDIILIEPNFNKYISISRIFRKIFLDYDINYSACGLDEATLDITEHLKNRISYSDKQRTFSCNVSCECRIPIQINSKQTKLFKICDECGKLIGAQEKTFSISSWSAVEELRFRIFARTQLTSSAGMASNGLLAKIVSDINKPNGQYHLSSDPWDINVFIKQLPVGKVPGIGKVSERKLDVLGIVKCEDF 1085
             VE ND        +A  S + +++ +Y ARK GVR GM    AK+LCP +  +  +F  Y  ++    +    Y  N  A   DEA +D T  L                                +L    DE    I                  R  +  +T  ++S GM SN LLA++ +   KPNGQY L   P +++ FI+   V  +PG+G+    KL  LG+  C D 
Sbjct:  556 GVEQND--------LAALSMAEIASCSYEARKAGVRNGMFFGQAKQLCPGLQSVPYDFQAYKEVALAMYETLASYTYNIEALSCDEALVDATALL-------------------------------AELGITPDELASAI------------------RTDVREKTGCSASIGMGSNILLARMATRKAKPNGQYFLR--PEEVDDFIRDQSVTSLPGVGRSMSSKLASLGVNTCGDL 733

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BLAST of DNA polymerase kappa vs. Ensembl Cavefish
Match: rev1 (REV1 DNA directed polymerase [Source:NCBI gene;Acc:103044976])

HSP 1 Score: 75.8702 bits (185), Expect = 8.323e-14
Identity = 65/237 (27.43%), Postives = 95/237 (40.08%), Query Frame = 3

Query:  375 AVEINDNPSLRTKPMAVGSSSMLSTSNYVARKFGVRAGMPGFIAKKLCPDIILIEPNFNKYISISRIFRKIFLDYDINYSACGLDEATLDITEHLKNRISYSDKQRTFSCNVSCECRIPIQINSKQTKLFKICDECGKLIGAQEKTFSISSWSAVEELRFRIFARTQLTSSAGMASNGLLAKIVSDINKPNGQYHLSSDPWDINVFIKQLPVGKVPGIGKVSERKLDVLGIVKCEDF 1085
             VE ND        +A  S + +++ +Y ARK GVR GM    AK+LCP +  +  +F  Y  ++    +    Y  N  A   DEA +D T  L                                +L    DE    I                  R  +  +T  ++S GM SN LLA++ +   KPNGQY L   P +++ FI+   V  +PG+G+    KL  LG+  C D 
Sbjct:  542 GVEQND--------LAALSMAEIASCSYEARKAGVRNGMFFGQAKQLCPGLQSVPYDFQAYKEVALAMYETLASYTYNIEALSCDEALVDATALL-------------------------------AELGITPDELASAI------------------RTDVREKTGCSASIGMGSNILLARMATRKAKPNGQYFLR--PEEVDDFIRDQSVTSLPGVGRSMSSKLASLGVNTCGDL 719

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BLAST of DNA polymerase kappa vs. Ensembl Sea Lamprey
Match: polk (polymerase (DNA directed) kappa [Source:ZFIN;Acc:ZDB-GENE-060526-137])

HSP 1 Score: 368.237 bits (944), Expect = 9.580e-118
Identity = 211/508 (41.54%), Postives = 302/508 (59.45%), Query Frame = 3

Query:   90 LKVNDNKAGMENLDKKKINETILEASRGSKYYEHEVXXXXXXXXXXXXXXXXYNSLSENDILRGVKKANKLLENISINRNLNQTFVHIDMDAYFAAVEINDNPSLRTKPMAVGSSSMLSTSNYVARKFGVRAGMPGFIAKKLCPDIILIEPNFNKYISISR-IFRKIFLDYDINYSACGLDEATLDITEHLKNRISYSDKQRTFSCNVS-CEC-----------------------RIPIQINSKQTKLFKICDECGKLIGAQEKT-----FSISSWSAVEELRFRIFARTQLTSSAGMASNGLLAKIVSDINKPNGQYHLSSDPWDINVFIKQLPVGKVPGIGKVSERKLDVLGIVKCEDFYHKRGALYHLFKPCMFSYFMRISLGXXXXXXXXXXXXXXXNGIDRKSMSVERTFPDCNDPILLMEKCKTLCKDLWKELLKKNLLGKCISIKLKLSSFEVRTRAFSNLEATNDLNNITNCACELLQTEINNNQPHKLCLRLLGVRIS 1523
            + +NDNKAGME LDK++IN+ IL+ S+GS++YE+E+KK ++  +++  + ++   L++  I +   + + L+E +  +R+LN+T VH+DMD ++AAVE+ D P L+ KPMAVGS SMLSTSNY AR+FGVRA MPGFIAKKLCPD+++   NFNKY ++S+ + R++  DYD N+    LDEA LDIT HL  R ++ + +RTF+ +   C+                          P Q+   +           +  GA E++     F +S   AV E+RFRI  +T LT+SAG+A N LLAK+ SD+NKPNGQY L      I  F+ +LP+ KV GIGKV+E+ L+ L +  C   + +R  +  LF      +F+RIS+G GS               +RKSMS ERTF + N    L   C  LC DL  +L K+ L G+ +++K K  SFEV+TRA S          I   A ELL+TE++N  P  L LRL+GVR+S
Sbjct:    1 MALNDNKAGMEGLDKERINKVILDISKGSRFYENELKKEQQVNQKIERMLQQKGQLTDQQIRQAELQMDSLVERLEKSRDLNRTIVHVDMDMFYAAVEMRDFPELKDKPMAVGSMSMLSTSNYHARRFGVRAAMPGFIAKKLCPDLVICPLNFNKYSAVSKQVVREVLADYDPNFLPMSLDEAYLDITAHLAERQAWPESRRTFAAHEGLCQTTDKQTDEANDGASFESYSPELFDSTPPQVGGSENAASGFGASASR-NGAPERSSTAVVFGLSVEEAVREMRFRIEQKTGLTASAGIAPNMLLAKVGSDMNKPNGQYRLEPTRDAIRNFVDELPIRKVSGIGKVTEKMLNALDVFTCAHLHRQRALVALLFSEGSCQHFLRISMGLGSTHVDRDG--------ERKSMSTERTFSEINKQEELYNLCWELCGDLANDLSKEGLKGRTVTVKTKSVSFEVKTRAMSLPGPVASREEIYAAAKELLKTEMDNISPQPLRLRLMGVRLS 499

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BLAST of DNA polymerase kappa vs. Ensembl Sea Lamprey
Match: ENSPMAT00000005239.1 (pep scaffold:Pmarinus_7.0:GL477257:209381:216639:1 gene:ENSPMAG00000004738.1 transcript:ENSPMAT00000005239.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 76.2554 bits (186), Expect = 9.739e-15
Identity = 66/279 (23.66%), Postives = 106/279 (37.99%), Query Frame = 3

Query:  342 FVHIDMDAYFAAVEINDNPSLRTKPMAV------GSS---------------------------------------------SMLSTSNYVARKFGVRAGMPGFIAKKLCPDIILIEPNFNKYISISRIFRKIFLDYDINYSACGLDEATLDITEHLKNRISYSDKQRTFSCNVSCECRIPIQINSKQTKLFKICDECGKLIGAQEKTFSISSWSAVEELRFRIFARTQLTSSAGMASNGLLAKIVSDINKPNGQYHLSSDPWDINVFIKQLPVGKVPG 1025
             +H+DMD +F +V I D P L+ KP+AV      GS                                              + +++ +Y AR+ GV+ GM    AK LCPD+  +  +F+ Y  +++   +    +     A   DEA LD+T  L +                                           GA  +  + +       +R  +FART+  +S GM SN LLA++ +   KP+GQ+HL  D   +  F++  PV  +PG
Sbjct:  420 IMHVDMDCFFVSVGIRDRPDLKGKPVAVTHTQGRGSQRPRPGADPHYEMQYYERKLDRGRTDGRGEGGGGGRVASDTAPMSMAEIASCSYEARRAGVKNGMFFGRAKLLCPDLQTVPYDFDGYREVAQALYETLASFTNEVEALSCDEAMLDVTAVLAD------------------------------------------TGAGPEELATA-------IRAEVFARTRCCASVGMGSNMLLARLATRKAKPDGQFHLRPD--VVEEFMRSQPVSSLPG 647

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BLAST of DNA polymerase kappa vs. Ensembl Nematostella
Match: EDO39102 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SB19])

HSP 1 Score: 352.443 bits (903), Expect = 6.278e-115
Identity = 196/487 (40.25%), Postives = 301/487 (61.81%), Query Frame = 3

Query:   90 LKVNDNKAGMENLDKKKINETILEASRGSKYYEHEVXXXXXXXXXXXXXXXXYNSLSENDILRGVKKANKLLENISINRNLNQTFVHIDMDAYFAAVEINDNPSLRTKPMAVGSSSMLSTSNYVARKFGVRAGMPGFIAKKLCPDIILIEPNFNKYISISRIFRKIFLDYDINYSACGLDEATLDITEHLKNRISYSDKQRTFSCNV----SCECRIPIQINSKQTKLFKICDECGKLIGAQEKT-----FSISSWSAVEELRFRIFARTQLTSSAGMASNGLLAKIVSDINKPNGQYHLSSDPWDINVFIKQLPVGKVPGIGKVSERKLDVLGIVKCEDFYHKRGALYHLFKPCMFSYFMRISLGXXXXXXXXXXXXXXXNGIDRKSMSVERTFPDCNDPILLMEKCKTLCKDLWKELLKKNLLGKCISIKLKLSSFEVRTRAFSNLEATNDLNNITNCACELLQTEINNNQPHKLCLRLLGVRIS 1523
            + +ND+KAGME LDK+KIN+ I E+S+GS++YE+E+K+ K+  +++    EK  + SE+++   + +A+++++ +   R++++T VH+DMDA++AAVE+ D+PSL+ KPMAVGS+SMLSTSNY AR++GVRA MPGFIAKKLCP +I++  +F+KY ++S+I R IF +YD  +    LDEA LD+T++L  R   ++K R F   V    S    +P +  S +        E   +    E       F       V+E+RFRI   TQLT+SAG+A N LLAK+ +D NKPNGQ++L  D  +I  F+K LP+ K+ GIG+VSE+ L  LG++ C D + KR  L  L       + + ++LG G+                RKS+  ERTF + ++P  L  +C+ LCK +  ++ ++ L  K ++IKLK  +FE++TR+ S  +       +   A +LL  EI   +P  L LRL+GVR+S
Sbjct:    2 MSLNDHKAGMEGLDKEKINKIIYESSKGSRFYENELKREKQVNERIKRQSEKLGACSEHELAEAMVEADRVVQELESGRDMSRTIVHVDMDAFYAAVEMRDDPSLKDKPMAVGSTSMLSTSNYPARRYGVRAAMPGFIAKKLCPHLIIVPLHFDKYRAVSKIVRGIFREYDPRFVPMSLDEAYLDLTDYLIERQRKTEK-RLFYKKVYRQTSPSAGVPSESESSEACGSNTAQESENVPSVAESVGEPIEFGNDVKDVVQEIRFRIENETQLTASAGIACNVLLAKVCTDCNKPNGQFYLKPDREEIVSFVKTLPIRKISGIGRVSEQMLKALGVITCADLFEKRDLLVLLHSDISSRFLIEVALGLGATRLETDR--------GRKSLGTERTFSEISNPAQLFSECEQLCKAIAVDMNEEGLRPKTVTIKLKTINFELKTRSVSFRQGITSEKELIASAFDLLGKEIKACEPKPLKLRLMGVRLS 479

[Close]

BLAST of DNA polymerase kappa vs. Ensembl Nematostella
Match: EDO29212 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T4A2])

HSP 1 Score: 347.436 bits (890), Expect = 1.178e-112
Identity = 193/485 (39.79%), Postives = 298/485 (61.44%), Query Frame = 3

Query:   90 LKVNDNKAGMENLDKKKINETILEASRGSKYYEHEVXXXXXXXXXXXXXXXXYNSLSENDILRGVKKANKLLENISINRNLNQTFVHIDMDAYFAAVEINDNPSLRTKPMAVGSSSMLSTSNYVARKFGVRAGMPGFIAKKLCPDIILIEPNFNKYISISRIFRKIFLDYDINYSACGLDEATLDITEHLKNRISYSDKQRTFSCNV----SCECRIPIQINSKQTKLFKICDECGKLIGAQEKT-----FSISSWSAVEELRFRIFARTQLTSSAGMASNGLLAKIVSDINKPNGQYHLSSDPWDINVFIKQLPVGKVPGIGKVSERKLDVLGIVKCEDFYHKRGALYHLFKPCMFSYFMRISLGXXXXXXXXXXXXXXXNGIDRKSMSVERTFPDCNDPILLMEKCKTLCKDLWKELLKKNLLGKCISIKLKLSSFEVRTRAFSNLEATNDLNNITNCACELLQTEINNNQPHKLCLRLLGVR 1517
            + +ND+KAGME LDK+KIN+ I E+S+GS++YE+E+K+ K+  +++    EK  + SE+++   + +A+++++ +   R++++T VH+DMDA++AAVE+ D+PSL+ KPMAVGS+SMLSTSNY AR++GVRA MPGFIAKKLCP +I++  +F+KY ++S+I R IF +YD  +    LDEA LD+T++L  R   ++K R F   V    S    +P +  S +        E   +    E       F       V+E+RFRI   TQLT+SAG+A N LLAK+ +D NKPNGQ++L  D  +I  F+K LP+ K+ GIG+VSE+ L  LG++ C D + KR  L  L       + + ++LG G+                RKS+  ERTF + ++P  L  +C+ LCK +  ++ ++ L  K ++IKLK  +FE++TR+ S  +       +   A +LL  EI   +P  L LRL+G +
Sbjct:    1 MSLNDHKAGMEGLDKEKINKIIYESSKGSRFYENELKREKQVNERIKRQSEKLGACSEHELAEAMVEADRVVQELESGRDMSRTIVHVDMDAFYAAVEMRDDPSLKDKPMAVGSTSMLSTSNYPARRYGVRAAMPGFIAKKLCPHLIIVPLHFDKYRAVSKIVRGIFREYDPRFVPMSLDEAYLDLTDYLIERQRKTEK-RLFYKKVYRQTSPSAGVPSESESSEACGSNTAQESENVPSVAESVGEPIEFGNDVKDVVQEIRFRIENETQLTASAGIACNVLLAKVCTDCNKPNGQFYLKPDREEIVSFVKTLPIRKISGIGRVSEQMLKALGVITCADLFEKRDLLVLLHSDISSRFLIEVALGLGATRLETDR--------GRKSLGTERTFSEISNPAQLFSECEQLCKAIAVDMNEEGLRPKTVTIKLKTINFELKTRSVSFRQGITSEKELIASAFDLLGKEIKACEPKPLKLRLMGYK 476

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BLAST of DNA polymerase kappa vs. Ensembl Nematostella
Match: EDO38905 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SBP1])

HSP 1 Score: 121.709 bits (304), Expect = 8.496e-30
Identity = 85/246 (34.55%), Postives = 128/246 (52.03%), Query Frame = 3

Query:  333 NQTFVHIDMDAYFAAVEINDNPSLRTKPMAVGSSSMLSTSNYVARKFGVRAGMPGFIAKKLCPDIILIE-PNFNKYISISRIFRKIFLDYDINYSACGLDEATLDITEHLKNRISYSDKQRTFSCNVSCECRIPIQINSKQTKLFKICDECGKLIGAQEKTFSISSWSAVEELRFRIFARTQLTSSAGMASNGLLAKIVSDINKPNGQYHLSSDPWDINVFIKQLPVGKVPGIGKVSERKLDVLGI 1067
            N+  VHID+D ++A VE+  NP LR +P+ V    +L T NYVAR  G++  +    AKK CPD+++I   +  KY   S    K+   + +     GLDE  +D++E ++ R+ ++ +    +  V C     I   S      ++C       G  E+  ++ S  A  ELR  IF    LT+ AG+A N LLAKI  + NKPN Q  L ++   +   +  LPV KVPGIG+ +  +L  LGI
Sbjct:    2 NRVIVHIDIDCFYAQVEMIRNPCLRDRPVGVSQKHILVTCNYVARAMGLKKLISLAEAKKKCPDLVIINGEDLTKYREFSSRVTKLLRRFALRVERLGLDENYVDVSELVQERMKHAPRGSYIA--VGCIYGDNILKGSSN----EVCP-----CGCHER-LTVGSVIA-SELRKAIFDEIGLTTCAGIAHNKLLAKIAGEQNKPNKQTLLYTE--RVEGLMGLLPVRKVPGIGRSTCARLGSLGI 232

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BLAST of DNA polymerase kappa vs. Ensembl Nematostella
Match: EDO49981 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7REV5])

HSP 1 Score: 100.908 bits (250), Expect = 4.660e-22
Identity = 99/391 (25.32%), Postives = 158/391 (40.41%), Query Frame = 3

Query:  333 NQTFVHIDMDAYFAAVEINDNPSLRTKPMAVG-----------------------------------------SSSMLSTSNYVARKFGVRAGMPGFIAKKLCPDIILIEPNFNKYISISRIFRKIFLDYDINYSACGLDEATLDITEHLKNRISYSDKQRTFSCNVSCECRIPIQINSKQTKLFKICDECGKLIGAQEKTFSISSWSAVEELRFRIFARTQLTSSAGMASNGLLAKIVSDINKPNGQYHLSSDPWDINVFIKQLPVGKVPGIGKVSERKLDVLGIVKCEDFYH-KRGALYHLFKPCMFSYFMRISLGXXXXXXXXXXXXXXXNGIDRKSMSVERT----FPDCNDPILLMEKCKTLCKDLWKELLKKNLLGKCISIKLKL 1367
             +  +HIDMD +F +V + D+P L  KP+AV                                          S S +++ +Y AR+ GVR GM    A+KLCPDI  +   F+KY  +S+   +I + Y  +  A   DEA LD+T                S +   E   P+ +                                 +++R  I A T+  +SAG++SN LLA++ + I KP+GQ++LS +  D+  F+       +PG+G    +KL+ +G+  C D       AL   F P       R   G                  +RKS+S E      F    + +  +E+   L  ++ K L +  L G+CI++KLK+
Sbjct:  283 GRVIMHIDMDCFFVSVYVRDHPELDGKPVAVSRFNGGGGCELKSSHIVNYEMSFPTGFVADLTSPDKSSAFFNSMSEIASCSYAARECGVRNGMFLGQARKLCPDITCVPYLFDKYRQVSQRLYEILVSYSHDIEAVSCDEAFLDVTH---------------SLDAGTE---PMAL--------------------------------AQQIRAEIRAATRCNASAGISSNVLLARMCTRIAKPDGQFYLSRED-DVIQFMASQKAKDLPGVGWALSKKLNDMGVETCADLQKLSLQALQKEFGPKTGLSLHRSCRGVDDRPLRVER--------ERKSVSAEINYGIRFTQDYEGVKFIEE---LAGEVHKRLREVGLKGRCITLKLKV 611

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BLAST of DNA polymerase kappa vs. Ensembl Nematostella
Match: EDO28363 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T6P5])

HSP 1 Score: 93.9745 bits (232), Expect = 7.427e-22
Identity = 84/295 (28.47%), Postives = 126/295 (42.71%), Query Frame = 3

Query:  546 FNKYISISRIFRKIFLDYDINYSACGLDEATLDITEHLKNRISYSDKQRTFSCNVSCECRIPIQINSKQTKLFKICDECGKLIGAQEKTFSISSWSAVEELRFRIFARTQLTSSAGMASNGLLAKIVSDINKPNGQYHLSSDPWDINVFIKQLPVGKVPGIGKVSERKLDVLGIVKCEDF-----------YHKRGA-LYHLFKPCMFSYFMRISLGXXXXXXXXXXXXXXXNGIDRKSMSVERTFPD-CNDPILLMEKCKTLCKDLWKELLKKNLLGKCISIKLKLSSFEVRTR 1391
            F +Y  IS   R IF +Y        LDEA LD+T++ K   S S                                    LI               +E+R RI+    L +SAG++ N  +AKI SDINKPNGQ  +  +P ++  F+++LP+ K  GIGKV+  K+   GI K  D            + K GA  YH+ +    S                   +   N + RKS++ ERTF +  +  I ++E+   +  +L K ++  N  GK I++K+K S F  +TR
Sbjct:    2 FGRYKEISSKIRAIFYEYTDLVEPLSLDEAYLDVTKNKKGNPSAS------------------------------------LIA--------------QEIRQRIWDELTLRASAGISINKFIAKIASDINKPNGQKTI--NPEEVVSFLEELPINKFFGIGKVTAAKMHNYGIFKGADLKKWTKEELEATFGKSGAQYYHIVRGIHNS-------------------QVKPNRV-RKSIAAERTFTENISSEIYMIERLDKIAVELEKRMVASNTKGKTITLKIKYSDFTQQTR 224

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BLAST of DNA polymerase kappa vs. Ensembl Medaka
Match: polk (DNA polymerase kappa [Source:NCBI gene;Acc:101163905])

HSP 1 Score: 367.851 bits (943), Expect = 7.625e-116
Identity = 218/503 (43.34%), Postives = 302/503 (60.04%), Query Frame = 3

Query:   72 EWELSSLKVNDNKAGMENLDKKKINETILEASRGSKYYEHEVXXXXXXXXXXXXXXXXYNSLSENDILRGVKKANKLLENISINRNLNQTFVHIDMDAYFAAVEINDNPSLRTKPMAVGSSSMLSTSNYVARKFGVRAGMPGFIAKKLCPDIILIEPNFNKYISISRIFRKIFLDYDINYSACGLDEATLDITEHLKNRISYSDKQRTFSCNVSC------ECRIPIQINSKQTKLFKIC-----------DECGKLIGAQEKTFSISSWSAVEELRFRIFARTQLTSSAGMASNGLLAKIVSDINKPNGQYHLSSDPWDINVFIKQLPVGKVPGIGKVSERKLDVLGIVKCEDFYHKRGALYHLFKPCMFSYFMRISLGXXXXXXXXXXXXXXXNGIDRKSMSVERTFPDCNDPILLMEKCKTLCKDLWKELLKKNLLGKCISIKLKLSSFEVRTRAFSNLEATNDLNNITNCACELLQTEINNNQPHKLCLRLLGVRISVL 1529
            E  LS + +NDNKAGME LD+ KIN  I+E+S+GSK+YE+E+KK ++  +++  +  +  ++++  + +   +  K+   +  +R+L++  VH+DMDA++AAVE+ D   L+TKPMAVGS SMLSTSNY+ARK+GVRA MPGFIAKKLC D++++ PNF+KY ++S   R+IF DYD ++    LDEA LD TEHL+ R ++ +  RT   +         E   P    +K   L  I            D      G  E  F  S   AV E+RFRI  +T LT+SAG+A N +LAK+ SD NKPNGQY L      +  FI+ LPV KV GIGKVSE+ L+ L I KC     +   L  LF       FM +SLG GS   S  E        +RKSMS+ERTF + +D       C+ LCKDL +++ K+ L GK +S+KLK  +FEV+TRA +   A      +   A +LL+TEI+N  PH L LRL+GVR+S  
Sbjct:   11 EGFLSRMALNDNKAGMEGLDRDKINNIIMESSKGSKFYENELKKDQQVNQRIEKMMLQKANITQAQLKKAQAQVEKMALALERSRDLSRVIVHVDMDAFYAAVEMRDCAELKTKPMAVGSMSMLSTSNYLARKYGVRAAMPGFIAKKLCSDLVIVPPNFDKYRAVSDEIREIFADYDPDFLPMSLDEAYLDFTEHLEQRQTWPESLRTHRYSSKSITTAVKETPNPKDTEAKDEDLSPILFNESPGSPPGLDGSKGANGGSE-LFGTSVEEAVREMRFRIEQKTMLTASAGIAPNMMLAKVCSDKNKPNGQYRLPPTREAVMDFIQDLPVRKVCGIGKVSEKMLNALEITKCSHLGQQMALLSLLFSETACQNFMEVSLGLGSTRISRHE--------ERKSMSIERTFKELSDAEEQYSLCRELCKDLAEDMKKEGLKGKTVSLKLKNVNFEVKTRAQTLQCAVAAEEELFAVAKDLLKTEIDNESPHPLKLRLMGVRMSAF 504

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BLAST of DNA polymerase kappa vs. Ensembl Medaka
Match: rev1 (REV1 DNA directed polymerase [Source:NCBI gene;Acc:101172774])

HSP 1 Score: 85.1149 bits (209), Expect = 1.367e-16
Identity = 80/319 (25.08%), Postives = 132/319 (41.38%), Query Frame = 3

Query:  420 AVGSSSMLSTSNYVARKFGVRAGMPGFIAKKLCPDIILIEPNFNKYISISRIFRKIFLDYDINYSACGLDEATLDITEHLKNRISYSDKQRTFSCNVSCECRIPIQINSKQTKLFKICDECGKLIGAQEKTFSISSWSAVEELRFRIFARTQLTSSAGMASNGLLAKIVSDINKPNGQYHLSSDPWDINVFIKQLPVGKVPGIGKVSERKLDVLGIVKCEDFYH-KRGALYHLFKPCMFSYFMRISLGXXXXXXXXXXXXXXXNGIDRKSMSVERTFPDCNDPILLMEKCKTLCKDLWKELLKK----NLLGKCISIKL 1361
            A  S + +++ +Y AR+ GVR GM    AK+LCP +  +  +F  Y  ++    +I   Y  +  A   DEA +D                                              G  + A+     IS     + +R  I  +T  ++S GM SN LLA++ +   KPNGQY L S+  +++ FI+ LPV ++PG+G V  +KL  LG+  C D        L  +F P       R   G         +        +RKS+S E  +   N     +E+ ++   +L  E+ K+     L G+ +++K+
Sbjct:  635 AALSMAEIASCSYEARQAGVRNGMFFGKAKQLCPSLQSVPYDFEAYKEVAINMYEILASYTRDIEALSCDEALID----------------------------------------------GSALLAE---LGISPDDLAQAIRADIKEKTGCSASVGMGSNILLARLATRKAKPNGQYFLKSE--EVDDFIRDLPVTRLPGVGHVMGKKLATLGVTTCGDLQQVSLSQLQRMFGPRTGQTLFRFCRGLDDRPVRCEK--------ERKSVSAEMNY---NIRFTKVEEAESFLSNLSMEVQKRLREAGLRGRRVTLKV 891

[Close]

BLAST of DNA polymerase kappa vs. Ensembl Medaka
Match: rev1 (REV1 DNA directed polymerase [Source:NCBI gene;Acc:101172774])

HSP 1 Score: 85.1149 bits (209), Expect = 1.432e-16
Identity = 80/319 (25.08%), Postives = 132/319 (41.38%), Query Frame = 3

Query:  420 AVGSSSMLSTSNYVARKFGVRAGMPGFIAKKLCPDIILIEPNFNKYISISRIFRKIFLDYDINYSACGLDEATLDITEHLKNRISYSDKQRTFSCNVSCECRIPIQINSKQTKLFKICDECGKLIGAQEKTFSISSWSAVEELRFRIFARTQLTSSAGMASNGLLAKIVSDINKPNGQYHLSSDPWDINVFIKQLPVGKVPGIGKVSERKLDVLGIVKCEDFYH-KRGALYHLFKPCMFSYFMRISLGXXXXXXXXXXXXXXXNGIDRKSMSVERTFPDCNDPILLMEKCKTLCKDLWKELLKK----NLLGKCISIKL 1361
            A  S + +++ +Y AR+ GVR GM    AK+LCP +  +  +F  Y  ++    +I   Y  +  A   DEA +D                                              G  + A+     IS     + +R  I  +T  ++S GM SN LLA++ +   KPNGQY L S+  +++ FI+ LPV ++PG+G V  +KL  LG+  C D        L  +F P       R   G         +        +RKS+S E  +   N     +E+ ++   +L  E+ K+     L G+ +++K+
Sbjct:  644 AALSMAEIASCSYEARQAGVRNGMFFGKAKQLCPSLQSVPYDFEAYKEVAINMYEILASYTRDIEALSCDEALID----------------------------------------------GSALLAE---LGISPDDLAQAIRADIKEKTGCSASVGMGSNILLARLATRKAKPNGQYFLKSE--EVDDFIRDLPVTRLPGVGHVMGKKLATLGVTTCGDLQQVSLSQLQRMFGPRTGQTLFRFCRGLDDRPVRCEK--------ERKSVSAEMNY---NIRFTKVEEAESFLSNLSMEVQKRLREAGLRGRRVTLKV 900

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BLAST of DNA polymerase kappa vs. Ensembl Medaka
Match: ENSORLT00000045125.1 (pep primary_assembly:ASM223467v1:9:1943765:1946356:-1 gene:ENSORLG00000024554.1 transcript:ENSORLT00000045125.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 49.2914 bits (116), Expect = 1.125e-6
Identity = 29/104 (27.88%), Postives = 51/104 (49.04%), Query Frame = 3

Query:  393 NPSLRTKPMAVGSSSMLSTSNYVARKFGVRAGMPGFIAKKLCPDIILIE-PNFNKYISISRIFRKIFLDYDINYSACGLDEATLDITEHLKNRISYSDKQRTFS 701
            +PSLR  P+ +    ++ T NYVAR+ GV   M    AK+ CP+++L+   +   Y   S    ++   +       G DE  +D+TE ++ R+  +     +S
Sbjct:    4 DPSLREVPLGIQQKYIIVTCNYVARERGVTKLMSVTDAKEKCPELVLVRGEDLTLYREASHQVTELLSSFCPLVERLGFDENFMDVTEMVERRMKETPPPEGYS 107

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BLAST of DNA polymerase kappa vs. Planmine SMEST
Match: SMESG000069346.1 (SMESG000069346.1)

HSP 1 Score: 1169.45 bits (3024), Expect = 0.000e+0
Identity = 604/608 (99.34%), Postives = 606/608 (99.67%), Query Frame = 3

Query:   66 MPEWELSSLKVNDNKAGMENLDKKKINETILEASRGSKYYEHEVXXXXXXXXXXXXXXXXYNSLSENDILRGVKKANKLLENISINRNLNQTFVHIDMDAYFAAVEINDNPSLRTKPMAVGSSSMLSTSNYVARKFGVRAGMPGFIAKKLCPDIILIEPNFNKYISISRIFRKIFLDYDINYSACGLDEATLDITEHLKNRISYSDKQRTFSCNVSCECRIPIQINSKQTKLFKICDECGKLIGAQEKTFSISSWSAVEELRFRIFARTQLTSSAGMASNGLLAKIVSDINKPNGQYHLSSDPWDINVFIKQLPVGKVPGIGKVSERKLDVLGIVKCEDFYHKRGALYHLFKPCMFSYFMRISLGXXXXXXXXXXXXXXXNGIDRKSMSVERTFPDCNDPILLMEKCKTLCKDLWKELLKKNLLGKCISIKLKLSSFEVRTRAFSNLEATNDLNNITNCACELLQTEINNNQPHKLCLRLLGVRISVLSMKLSPLATLTQLNIKEAFKNQEMKAESTKKEEGVNHEEQLKEKCSSEVIKDDSIVQCPVCFVSVNISNINTHLDFCISPANSEQPSTSTYVPTLKRSAPVNSKSRSKIPRCNSNRLFEK 1889
            MPEWELSSLKVNDNKAGMENLDKKKINETILEASRGSKYYEHEVKKAKEFEKQLLLLKEKYNSLSENDILRGVKKANKLLENISINRNLNQTFVHIDMDAYFAAVEINDNPSLRTKPMAVGSSSMLSTSNYVARKFGVRAGMPGFIAKKLCP+IILIEPNFNKYISISRIFRKIFLDYDINYSACGLDEATLDITEHLKNRISYSDKQRTFSCNVSCECRIPIQINSKQTKLFKICDECGKLIGAQEKTFSISSWSAVEELRFRIFA TQLTSSAGMASNGLLAKIVSDINKPNGQYHLSSDPWDINVFIKQLPVGKVPGIGKVSERKLDVLGIVKCEDFYHKRGALYHLFKPCMFSYFMRISLGEGSHEF EVESEENSNGIDRKSMSVERTFPDCNDPILLMEKCKTLCKDLWKELLKKNLLGKCISIKLKLSSFEVRTRAFSNLEATNDLNNITNCACELLQTEINN+QPHKLCLRLLGVRISVLSMKLSPLATLTQLNIKEAFKNQEMKAESTKKEEGVNHEEQLKEKCSSEVIKDDSIVQCPVCFVSVNISNINTHLDFCISPANSEQPSTSTYVPTLKRSAPVNSKSRSKIPRCNSNRLFEK
Sbjct:    1 MPEWELSSLKVNDNKAGMENLDKKKINETILEASRGSKYYEHEVKKAKEFEKQLLLLKEKYNSLSENDILRGVKKANKLLENISINRNLNQTFVHIDMDAYFAAVEINDNPSLRTKPMAVGSSSMLSTSNYVARKFGVRAGMPGFIAKKLCPNIILIEPNFNKYISISRIFRKIFLDYDINYSACGLDEATLDITEHLKNRISYSDKQRTFSCNVSCECRIPIQINSKQTKLFKICDECGKLIGAQEKTFSISSWSAVEELRFRIFASTQLTSSAGMASNGLLAKIVSDINKPNGQYHLSSDPWDINVFIKQLPVGKVPGIGKVSERKLDVLGIVKCEDFYHKRGALYHLFKPCMFSYFMRISLGEGSHEFPEVESEENSNGIDRKSMSVERTFPDCNDPILLMEKCKTLCKDLWKELLKKNLLGKCISIKLKLSSFEVRTRAFSNLEATNDLNNITNCACELLQTEINNDQPHKLCLRLLGVRISVLSMKLSPLATLTQLNIKEAFKNQEMKAESTKKEEGVNHEEQLKEKCSSEVIKDDSIVQCPVCFVSVNISNINTHLDFCISPANSEQPSTSTYVPTLKRSAPVNSKSRSKIPRCNSNRLFEK 608

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BLAST of DNA polymerase kappa vs. Planmine SMEST
Match: SMESG000019910.1 (SMESG000019910.1)

HSP 1 Score: 112.464 bits (280), Expect = 1.823e-25
Identity = 80/262 (30.53%), Postives = 121/262 (46.18%), Query Frame = 3

Query:  339 TFVHIDMDAYFAAVEINDNPSLRTKPM--------------AVGSSSMLSTSNYVARKFGVRAGMPGFIAKKLCPDIILIEPNFNKYISISRIFRKIFLDYDINYSACGLDEATLDITEHLKNRISYSDKQRTFSCNVSCECRIPIQINSKQTKLFKICDECGKLIGAQEKTFSISSWSAVEELRFRIFARTQLTSSAGMASNGLLAKIVSDINKPNGQYHL-SSDPWDINVFIKQLPVGKVPGIGKVSERKLDVLGIVKCE 1079
             F+H+DMD +F +V I D P L+ KP+               VGS S +++S+YVARKFG++ GM    AK LCP++I I  +F  Y+ +++   +    +  N      DE  +D+ + LK                       +   S   + F I                I+      + R  I   TQ ++S G+ SN L+ K+ ++  KP+G+Y L ++D  D   FIK + V  +PGIGKV E KL  L I  CE
Sbjct:  220 VFMHVDMDCFFVSVGIRDKPELKDKPVVVTHSTRGHSSNASTVGSMSEIASSSYVARKFGIKNGMHLGKAKTLCPNLITIPYDFEMYLEVAKTLYRTASKFTHNIEVGSCDELYIDLIDILK-----------------------VHRESDSLEQFSI----------------INPILFANQFRNIISKETQCSASCGIGSNLLICKLATNKAKPDGEYWLKTADAID---FIKSMNVRDLPGIGKVLEDKLKSLNITNCE 439

[Close]

BLAST of DNA polymerase kappa vs. Planmine SMEST
Match: SMESG000019910.1 (SMESG000019910.1)

HSP 1 Score: 112.079 bits (279), Expect = 2.186e-25
Identity = 80/262 (30.53%), Postives = 121/262 (46.18%), Query Frame = 3

Query:  339 TFVHIDMDAYFAAVEINDNPSLRTKPM--------------AVGSSSMLSTSNYVARKFGVRAGMPGFIAKKLCPDIILIEPNFNKYISISRIFRKIFLDYDINYSACGLDEATLDITEHLKNRISYSDKQRTFSCNVSCECRIPIQINSKQTKLFKICDECGKLIGAQEKTFSISSWSAVEELRFRIFARTQLTSSAGMASNGLLAKIVSDINKPNGQYHL-SSDPWDINVFIKQLPVGKVPGIGKVSERKLDVLGIVKCE 1079
             F+H+DMD +F +V I D P L+ KP+               VGS S +++S+YVARKFG++ GM    AK LCP++I I  +F  Y+ +++   +    +  N      DE  +D+ + LK                       +   S   + F I                I+      + R  I   TQ ++S G+ SN L+ K+ ++  KP+G+Y L ++D  D   FIK + V  +PGIGKV E KL  L I  CE
Sbjct:  220 VFMHVDMDCFFVSVGIRDKPELKDKPVVVTHSTRGHSSNASTVGSMSEIASSSYVARKFGIKNGMHLGKAKTLCPNLITIPYDFEMYLEVAKTLYRTASKFTHNIEVGSCDELYIDLIDILK-----------------------VHRESDSLEQFSI----------------INPILFANQFRNIISKETQCSASCGIGSNLLICKLATNKAKPDGEYWLKTADAID---FIKSMNVRDLPGIGKVLEDKLKSLNITNCE 439

[Close]

BLAST of DNA polymerase kappa vs. Planmine SMEST
Match: SMESG000010346.1 (SMESG000010346.1)

HSP 1 Score: 52.7582 bits (125), Expect = 6.544e-7
Identity = 63/245 (25.71%), Postives = 93/245 (37.96%), Query Frame = 3

Query:  333 NQTFVHIDMDAYFAAVEINDNPSLRTKPMAVGSSSMLSTSN-----------YVARKFGVRAGMPGFIAKKLCPDIILI-------EPNFNKYISISRIFRKIFLDYDINYSACGLDEATLDITEHLKNR-ISYSD-------KQRTFSCNVSCECRIPIQINSKQTKLFKI------CDECGKLIGAQEKTFSISSWSAVEELRFRIFARTQLTSSAGMASNGLLAKIVSDINKPNGQYHLSSD 971
            N   V IDMD ++  VE      L+  P  VG  S +   N           Y AR  GV   M G  AK+ CPDI L        + +  KY +      K    +        +DEA +DIT+ + N  +S +D       K R       C     +  N     L ++      CD+    +GA            V+++R  ++       SAG+A +   AK    ++KPN Q  + SD
Sbjct:    4 NPIIVLIDMDCFYVQVE------LKAAPQYVGKESAVVQYNTWRGGGIIAVSYEARAKGVNRSMRGDEAKQKCPDIHLFSVPENRGKADLTKYRNAGAEVIKCLSKHASCVERASIDEAFIDITDEVDNLLVSLTDLGELAMLKDRRDRSIEGCHAVGYVSYNDWLDHLMELRATDEQCDDVRLALGA----------FLVQQMREDVYNSLGYRCSAGIAHSKTTAKFACGVHKPNQQTLVPSD 232

[Close]

BLAST of DNA polymerase kappa vs. Planmine SMEST
Match: SMESG000010350.1 (SMESG000010350.1)

HSP 1 Score: 51.2174 bits (121), Expect = 1.994e-6
Identity = 65/264 (24.62%), Postives = 101/264 (38.26%), Query Frame = 3

Query:  333 NQTFVHIDMDAYFAAVEINDNPSLRTKPMAVGSSSMLSTSN-----------YVARKFGVRAGMPGFIAKKLCPDIILI-------EPNFNKYISISRIFRKIFLDYDINYSACGLDEATLDITEHLKNR-ISYSD-------KQRTFSCNVSCECRIPIQINSKQTKLFKI------CDECGKLIGAQEKTFSISSWSAVEELRFRIFARTQLTSSAGMASNGLLAKIVSDINKPNGQYHLSSDPWDINVFIKQLPVGKVPGI 1028
            N   V IDMD ++  VE      L+  P  VG  S +   N           Y AR  GV   M G  AK+ CPDI L        + +  KY +      K    +        +DEA +DIT+ + N  +S +D       K R       C     +  +     L ++      CD+    +GA            V+++R  ++       SAG+A +   AK    ++KPN Q  + SD   I+  +    + K+P +
Sbjct:    4 NPIIVLIDMDCFYVQVE------LKAAPQYVGKESAVVQYNTWRGGGIIAVSYEARAKGVNRSMRGDEAKQKCPDIHLFSVPENRGKADLTKYRNAGAEVIKCLSKHASCVERASIDEAFIDITDEVDNLLVSLTDLGELAMLKDRRDRSIEGCHAVGYVSYSDWLDHLMELRATDEQCDDVRLALGA----------FLVQQMREDVYNSLGYRCSAGIAHSKTTAKFACGVHKPNQQTLVPSD--RISDLMNNASIDKMPWL 249

The following BLAST results are available for this feature:

BLAST of DNA polymerase kappa vs. Ensembl Human
BLAST of DNA polymerase kappa vs. Ensembl Celegans
BLAST of DNA polymerase kappa vs. Ensembl Fly
BLAST of DNA polymerase kappa vs. Ensembl Zebrafish
BLAST of DNA polymerase kappa vs. Ensembl Xenopus
BLAST of DNA polymerase kappa vs. Ensembl Mouse
BLAST of DNA polymerase kappa vs. UniProt/SwissProt
BLAST of DNA polymerase kappa vs. TrEMBL
BLAST of DNA polymerase kappa vs. Ensembl Cavefish
BLAST of DNA polymerase kappa vs. Ensembl Sea Lamprey
BLAST of DNA polymerase kappa vs. Ensembl Yeast
BLAST of DNA polymerase kappa vs. Ensembl Nematostella
BLAST of DNA polymerase kappa vs. Ensembl Medaka
BLAST of DNA polymerase kappa vs. Planmine SMEST

BLAST of DNA polymerase kappa vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
POLK	5.570e-117	38.02	DNA polymerase kappa [Source:HGNC Symbol;Acc:HGNC:...	[more]
POLK	7.997e-103	41.89	DNA polymerase kappa [Source:HGNC Symbol;Acc:HGNC:...	[more]
POLK	1.672e-102	41.89	DNA polymerase kappa [Source:HGNC Symbol;Acc:HGNC:...	[more]
POLK	3.186e-102	41.89	DNA polymerase kappa [Source:HGNC Symbol;Acc:HGNC:...	[more]
POLK	3.933e-97	42.51	DNA polymerase kappa [Source:HGNC Symbol;Acc:HGNC:...	[more]

BLAST of DNA polymerase kappa vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 4


Match Name	E-value	Identity	Description
polk-1	1.690e-93	37.07	DNA polymerase kappa [Source:UniProtKB/Swiss-Prot...	[more]
polk-1	3.587e-56	33.41	DNA polymerase kappa [Source:UniProtKB/Swiss-Prot...	[more]
polh-1	2.009e-12	25.28	DNA polymerase eta; POLH (DNA polymerase eta) homo...	[more]
rev-1	6.074e-12	23.86	DNA repair protein REV1 [Source:UniProtKB/TrEMBL;...	[more]

BLAST of DNA polymerase kappa vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
DNApol-iota	3.981e-16	28.52	gene:FBgn0037554 transcript:FBtr0081797	[more]
DNApol-iota	3.981e-16	28.52	gene:FBgn0037554 transcript:FBtr0081798	[more]
DNApol-iota	3.981e-16	28.52	gene:FBgn0037554 transcript:FBtr0339606	[more]
DNApol-eta	7.674e-15	26.15	gene:FBgn0037141 transcript:FBtr0078489	[more]
Rev1	3.568e-11	21.85	gene:FBgn0035150 transcript:FBtr0072557	[more]

BLAST of DNA polymerase kappa vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
polk	2.749e-119	43.87	polymerase (DNA directed) kappa [Source:ZFIN;Acc:Z...	[more]
polk	4.858e-118	43.90	polymerase (DNA directed) kappa [Source:ZFIN;Acc:Z...	[more]
poli	8.689e-24	31.75	polymerase (DNA directed) iota [Source:ZFIN;Acc:ZD...	[more]
rev1	1.011e-14	28.38	REV1 DNA directed polymerase [Source:ZFIN;Acc:ZDB-...	[more]
rev1	1.011e-14	28.38	REV1 DNA directed polymerase [Source:ZFIN;Acc:ZDB-...	[more]

BLAST of DNA polymerase kappa vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
sec31a	3.949e-123	41.96	SEC31 homolog A, COPII coat complex component [Sou...	[more]
sec31a	7.056e-123	36.94	SEC31 homolog A, COPII coat complex component [Sou...	[more]
sec31a	3.486e-122	37.77	SEC31 homolog A, COPII coat complex component [Sou...	[more]
sec31a	3.894e-122	37.52	SEC31 homolog A, COPII coat complex component [Sou...	[more]
sec31a	4.256e-122	37.40	SEC31 homolog A, COPII coat complex component [Sou...	[more]

BLAST of DNA polymerase kappa vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Polk	2.355e-119	40.59	polymerase (DNA directed), kappa [Source:MGI Symbo...	[more]
Polk	4.941e-119	40.93	polymerase (DNA directed), kappa [Source:MGI Symbo...	[more]
Polk	1.973e-108	40.91	polymerase (DNA directed), kappa [Source:MGI Symbo...	[more]
Polk	1.847e-104	40.08	polymerase (DNA directed), kappa [Source:MGI Symbo...	[more]
Polk	1.874e-104	39.71	polymerase (DNA directed), kappa [Source:MGI Symbo...	[more]

BLAST of DNA polymerase kappa vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q9QUG2\|POLK_MOUSE	3.456e-118	40.93	DNA polymerase kappa OS=Mus musculus OX=10090 GN=P...	[more]
sp\|Q9UBT6\|POLK_HUMAN	2.675e-116	38.02	DNA polymerase kappa OS=Homo sapiens OX=9606 GN=PO...	[more]
sp\|P34409\|POLK_CAEEL	2.149e-92	37.07	DNA polymerase kappa OS=Caenorhabditis elegans OX=...	[more]
sp\|Q6JDV7\|POLK_ARATH	1.773e-91	38.02	DNA polymerase kappa OS=Arabidopsis thaliana OX=37...	[more]
sp\|O74944\|POLK_SCHPO	2.634e-62	29.93	DNA polymerase kappa OS=Schizosaccharomyces pombe ...	[more]

BLAST of DNA polymerase kappa vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A2C9JXS0	5.351e-127	43.83	UmuC domain-containing protein OS=Biomphalaria gla...	[more]
R7T7Z3	8.692e-127	40.20	UmuC domain-containing protein OS=Capitella teleta...	[more]
A0A433T4X4	3.917e-126	41.30	UmuC domain-containing protein (Fragment) OS=Elysi...	[more]
V4BHH4	4.215e-125	46.94	UmuC domain-containing protein OS=Lottia gigantea ...	[more]
A0A218VA30	8.688e-123	37.09	DNA polymerase kappa OS=Lonchura striata domestica...	[more]

BLAST of DNA polymerase kappa vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
polk	8.099e-118	43.47	DNA polymerase kappa [Source:NCBI gene;Acc:1030468...	[more]
poli	4.822e-20	30.47	DNA polymerase iota [Source:NCBI gene;Acc:10304428...	[more]
poli	5.194e-20	30.47	DNA polymerase iota [Source:NCBI gene;Acc:10304428...	[more]
rev1	8.209e-14	27.43	REV1 DNA directed polymerase [Source:NCBI gene;Acc...	[more]
rev1	8.323e-14	27.43	REV1 DNA directed polymerase [Source:NCBI gene;Acc...	[more]

BLAST of DNA polymerase kappa vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 2


Match Name	E-value	Identity	Description
polk	9.580e-118	41.54	polymerase (DNA directed) kappa [Source:ZFIN;Acc:Z...	[more]
ENSPMAT00000005239.1	9.739e-15	23.66	pep scaffold:Pmarinus_7.0:GL477257:209381:216639:1...	[more]

BLAST of DNA polymerase kappa vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of DNA polymerase kappa vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO39102	6.278e-115	40.25	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO29212	1.178e-112	39.79	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO38905	8.496e-30	34.55	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO49981	4.660e-22	25.32	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO28363	7.427e-22	28.47	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of DNA polymerase kappa vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 4


Match Name	E-value	Identity	Description
polk	7.625e-116	43.34	DNA polymerase kappa [Source:NCBI gene;Acc:1011639...	[more]
rev1	1.367e-16	25.08	REV1 DNA directed polymerase [Source:NCBI gene;Acc...	[more]
rev1	1.432e-16	25.08	REV1 DNA directed polymerase [Source:NCBI gene;Acc...	[more]
ENSORLT00000045125.1	1.125e-6	27.88	pep primary_assembly:ASM223467v1:9:1943765:1946356...	[more]

BLAST of DNA polymerase kappa vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000069346.1	0.000e+0	99.34	SMESG000069346.1	[more]
SMESG000019910.1	1.823e-25	30.53	SMESG000019910.1	[more]
SMESG000019910.1	2.186e-25	30.53	SMESG000019910.1	[more]
SMESG000010346.1	6.544e-7	25.71	SMESG000010346.1	[more]
SMESG000010350.1	1.994e-6	24.62	SMESG000010350.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30017662 ID=SMED30017662|Name=DNA polymerase kappa|organism=Schmidtea mediterranea sexual|type=transcript|length=1964bp
TAAATATTACATTATTTAATATTAAATTGTAATTTGATCATTACAATTTG
ATTAGTAATTTAAATATGCCTGAATGGGAACTTTCTTCGTTGAAAGTAAA
TGATAATAAAGCTGGTATGGAAAATTTAGATAAGAAGAAAATTAATGAAA
CAATTTTGGAAGCATCAAGAGGAAGTAAATATTATGAACATGAAGTCAAA
AAAGCTAAAGAATTTGAAAAACAACTTTTATTGCTCAAGGAAAAATATAA
TTCCTTGTCTGAAAATGATATTTTAAGAGGTGTAAAGAAGGCTAACAAAT
TGCTTGAAAATATTTCTATAAATCGTAATTTAAACCAAACATTTGTTCAT
ATTGATATGGACGCATACTTTGCTGCTGTTGAAATAAACGATAACCCATC
TTTACGTACTAAACCTATGGCAGTTGGTTCGTCAAGTATGCTTTCAACAA
GCAATTATGTAGCGAGGAAATTTGGTGTTAGAGCTGGAATGCCAGGATTT
ATTGCCAAGAAACTTTGCCCAGATATTATTCTTATCGAGCCAAATTTCAA
TAAATATATATCAATTAGTCGAATATTTCGAAAGATATTCTTAGATTACG
ATATAAATTATTCTGCATGCGGTCTGGATGAAGCAACACTCGATATAACT
GAGCATTTAAAAAACCGCATAAGCTATTCAGATAAACAAAGAACATTTTC
TTGTAATGTATCATGCGAATGCCGGATACCTATTCAAATCAATAGCAAAC
AAACTAAACTATTTAAAATTTGTGATGAATGCGGAAAGCTGATTGGAGCA
CAAGAAAAGACCTTTTCCATTAGCTCATGGAGTGCCGTTGAAGAGCTACG
TTTTCGAATATTTGCCAGAACTCAATTGACGTCCAGTGCCGGAATGGCAT
CCAACGGATTACTGGCCAAGATCGTATCCGATATAAACAAACCTAATGGG
CAATATCATCTCTCCTCCGATCCATGGGACATCAATGTTTTCATCAAGCA
ATTGCCAGTTGGGAAGGTTCCCGGTATTGGGAAAGTATCGGAACGTAAAT
TAGATGTATTGGGTATTGTGAAATGTGAAGATTTTTATCATAAAAGGGGC
GCACTTTATCATTTGTTTAAACCGTGTATGTTTTCGTATTTCATGAGAAT
ATCTCTTGGAGAGGGAAGTCATGAATTTTCTGAGGTTGAATCTGAAGAAA
ATTCAAACGGGATCGATAGGAAAAGTATGAGTGTTGAAAGAACATTCCCA
GATTGTAATGATCCGATACTATTAATGGAAAAATGTAAGACGTTATGTAA
GGACTTATGGAAAGAGTTATTAAAAAAAAATCTACTGGGTAAATGCATTT
CCATTAAATTGAAATTGTCTAGTTTTGAAGTGAGAACTCGAGCTTTTAGT
AATTTAGAAGCTACTAATGATCTTAATAACATAACTAATTGTGCATGCGA
GTTACTTCAAACAGAAATCAACAATAATCAACCTCACAAACTTTGCTTAA
GACTTTTGGGAGTGAGAATAAGTGTATTAAGTATGAAATTATCTCCCCTG
GCTACGTTGACTCAACTTAACATAAAAGAAGCTTTCAAAAATCAAGAAAT
GAAAGCTGAATCAACAAAAAAAGAAGAGGGTGTAAACCATGAAGAGCAAT
TGAAAGAGAAATGTAGTTCTGAGGTAATAAAGGATGATTCAATTGTGCAA
TGCCCTGTCTGCTTTGTCTCTGTGAATATATCAAATATAAATACACATCT
TGATTTCTGCATTTCGCCCGCAAATTCTGAACAACCATCCACCTCAACAT
ATGTTCCTACTCTCAAACGATCAGCTCCGGTAAACTCAAAAAGTCGTTCA
AAGATTCCTCGATGCAATAGTAACCGACTTTTTGAAAAATGATTCTGTGC
TAAAATTAGATTTTTGTGAATGTTTTCTATCAATGATTATTATTGGTTCG
GAATAAAATTCGAT

protein sequence of SMED30017662-orf-1

>SMED30017662-orf-1 ID=SMED30017662-orf-1|Name=SMED30017662-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=609bp
MPEWELSSLKVNDNKAGMENLDKKKINETILEASRGSKYYEHEVKKAKEF
EKQLLLLKEKYNSLSENDILRGVKKANKLLENISINRNLNQTFVHIDMDA
YFAAVEINDNPSLRTKPMAVGSSSMLSTSNYVARKFGVRAGMPGFIAKKL
CPDIILIEPNFNKYISISRIFRKIFLDYDINYSACGLDEATLDITEHLKN
RISYSDKQRTFSCNVSCECRIPIQINSKQTKLFKICDECGKLIGAQEKTF
SISSWSAVEELRFRIFARTQLTSSAGMASNGLLAKIVSDINKPNGQYHLS
SDPWDINVFIKQLPVGKVPGIGKVSERKLDVLGIVKCEDFYHKRGALYHL
FKPCMFSYFMRISLGEGSHEFSEVESEENSNGIDRKSMSVERTFPDCNDP
ILLMEKCKTLCKDLWKELLKKNLLGKCISIKLKLSSFEVRTRAFSNLEAT
NDLNNITNCACELLQTEINNNQPHKLCLRLLGVRISVLSMKLSPLATLTQ
LNIKEAFKNQEMKAESTKKEEGVNHEEQLKEKCSSEVIKDDSIVQCPVCF
VSVNISNINTHLDFCISPANSEQPSTSTYVPTLKRSAPVNSKSRSKIPRC
NSNRLFEK*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0002109	X1 cell

Vocabulary: **INTERPRO**
Term	Definition
IPR036775	DNA_pol_Y-fam_lit_finger_sf
IPR022880	DNApol_IV
IPR006642	Znf_Rad18_put
IPR017961	DNA_pol_Y-fam_little_finger
IPR024728	PolY_HhH_motif
IPR001126	UmuC

Vocabulary: **molecular function**
Term	Definition
GO:0003677	DNA binding
GO:0003684	damaged DNA binding
GO:0016779	nucleotidyltransferase activity
GO:0046872	metal ion binding
GO:0003887	DNA-directed DNA polymerase activity
GO:0005515	protein binding
GO:0016740	transferase activity

Vocabulary: **biological process**
Term	Definition
GO:0006281	DNA repair
GO:0071897	DNA biosynthetic process
GO:0006260	DNA replication
GO:0006297	nucleotide-excision repair, DNA gap filling
GO:0006974	cellular response to DNA damage stimulus

Vocabulary: **cellular component**
Term	Definition
GO:0005634	nucleus
GO:0005654	nucleoplasm
GO:0016604	nuclear body

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
None	No IPR available	COILS	Coil	Coil	coord: 40..67
None	No IPR available	GENE3D	G3DSA:3.30.160.60		coord: 542..570 e-value: 1.3E-6 score: 30.0
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 576..597
None	No IPR available	PANTHER	PTHR11076:SF33	DNA POLYMERASE KAPPA	coord: 3..585
None	No IPR available	PANTHER	PTHR11076	DNA REPAIR POLYMERASE UMUC / TRANSFERASE FAMILY MEMBER	coord: 3..585
None	No IPR available	SUPERFAMILY	SSF56672	DNA/RNA polymerases	coord: 75..368
IPR006642	Zinc finger, Rad18-type putative	SMART	SM00734	c2hc_5	coord: 543..566 e-value: 5.4E-5 score: 32.6
IPR024728	DNA polymerase type-Y, HhH motif	PFAM	PF11798	IMS_HHH	coord: 306..334 e-value: 4.3E-6 score: 26.7
IPR001126	UmuC domain	PFAM	PF00817	IMS	coord: 96..289 e-value: 3.1E-34 score: 118.1
IPR001126	UmuC domain	PROSITE	PS50173	UMUC	coord: 93..322 score: 49.857
IPR036775	DNA polymerase, Y-family, little finger domain superfamily	GENE3D	G3DSA:3.30.1490.100		coord: 385..492 e-value: 2.6E-27 score: 97.3
IPR036775	DNA polymerase, Y-family, little finger domain superfamily	SUPERFAMILY	SSF100879	Lesion bypass DNA polymerase (Y-family), little finger domain	coord: 385..486
IPR017961	DNA polymerase, Y-family, little finger domain	PFAM	PF11799	IMS_C	coord: 385..489 e-value: 5.2E-12 score: 46.5
IPR022880	DNA polymerase IV	CDD	cd03586	PolY_Pol_IV_kappa	coord: 94..486 e-value: 1.00555E-111 score: 336.03

Main menu

DNA polymerase kappa

Zeng et. al., 2018

▻ Overview

▻ Neoblast Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 1

Owlery

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