Cathepsin L

Overview
NameCathepsin L
Smed IDSMED30017650
Length (bp)1091
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Cathepsin L (SMED30017650) t-SNE clustered cells

Violin plots show distribution of expression levels for Cathepsin L (SMED30017650) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Cathepsin L (SMED30017650) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Cathepsin L (SMED30017650) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30017650

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 2

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
head regionSMED30017650SMESG000063517.1 SmedASXL_013595SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016
whole organism asexual adult RNA-sequencing evidence
pigment cellSMED30017650SMESG000063517.1 SMED30017650smed_20140614PMID:22884275
Lapan et al., 2012
whole organism asexual adult colorimetric in situ hybridization evidence
Note: Hover over icons to view figure legend
Homology
BLAST of Cathepsin L vs. Ensembl Human
Match: CTSV (cathepsin V [Source:HGNC Symbol;Acc:HGNC:2538])

HSP 1 Score: 211.46 bits (537), Expect = 3.369e-65
Identity = 122/327 (37.31%), Postives = 183/327 (55.96%), Query Frame = 2
Query:  119 MVSLLSRYDGEFQT----FKQRYNKSYSSMHEENSRFLNFISSLLEINHHNQLYENGQKSYEIGINHLSDWSGEELAQLTK-LKQSNLTGSSYLSSNVKIDLPDSFDWREKGAVTEVKNQGFCGSCYAFATTGTLEAQIWRKTGKLISLSEQQIV--XXXXXXXXXXXXFVQDALSYIKSNGGIENEESYPYISSETFKPNSKCNFFKSKVVATDTGFVQMPANDETKMKEALVTIGPISVAISAT-KSLKRYTSGIFHEDECDKLKLNHAVLIVGYGTD--QTSGTPYWIIKNSWSSFWGENGYFRLPRNI-NACKVAMMPVYPLV 1066
            + S + ++D    T    +K  + + Y + +EE  R   +  ++  I  HN  Y  G+  + + +N   D + EE  Q+    +             + +DLP S DWR+KG VT VKNQ  CGSC+AF+ TG LE Q++RKTGKL+SLSEQ +V       + GC+GGF+  A  Y+K NGG+++EESYPY++ +       C +     VA DTGF  +    E  + +A+ T+GPISVA+ A   S + Y SGI+ E +C    L+H VL+VGYG +   ++ + YW++KNSW   WG NGY ++ ++  N C +A    YP V
Sbjct:   14 IASAVPKFDQNLDTKWYQWKATHRRLYGA-NEEGWRRAVWEKNMKMIELHNGEYSQGKHGFTMAMNAFGDMTNEEFRQMMGCFRNQKFRKGKVFREPLFLDLPKSVDWRKKGYVTPVKNQKQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQGNQGCNGGFMARAFQYVKENGGLDSEESYPYVAVDEI-----CKYRPENSVANDTGFTVVAPGKEKALMKAVATVGPISVAMDAGHSSFQFYKSGIYFEPDCSSKNLDHGVLVVGYGFEGANSNNSKYWLVKNSWGPEWGSNGYVKIAKDKNNHCGIATAASYPNV 334          
BLAST of Cathepsin L vs. Ensembl Human
Match: CTSV (cathepsin V [Source:HGNC Symbol;Acc:HGNC:2538])

HSP 1 Score: 211.46 bits (537), Expect = 3.369e-65
Identity = 122/327 (37.31%), Postives = 183/327 (55.96%), Query Frame = 2
Query:  119 MVSLLSRYDGEFQT----FKQRYNKSYSSMHEENSRFLNFISSLLEINHHNQLYENGQKSYEIGINHLSDWSGEELAQLTK-LKQSNLTGSSYLSSNVKIDLPDSFDWREKGAVTEVKNQGFCGSCYAFATTGTLEAQIWRKTGKLISLSEQQIV--XXXXXXXXXXXXFVQDALSYIKSNGGIENEESYPYISSETFKPNSKCNFFKSKVVATDTGFVQMPANDETKMKEALVTIGPISVAISAT-KSLKRYTSGIFHEDECDKLKLNHAVLIVGYGTD--QTSGTPYWIIKNSWSSFWGENGYFRLPRNI-NACKVAMMPVYPLV 1066
            + S + ++D    T    +K  + + Y + +EE  R   +  ++  I  HN  Y  G+  + + +N   D + EE  Q+    +             + +DLP S DWR+KG VT VKNQ  CGSC+AF+ TG LE Q++RKTGKL+SLSEQ +V       + GC+GGF+  A  Y+K NGG+++EESYPY++ +       C +     VA DTGF  +    E  + +A+ T+GPISVA+ A   S + Y SGI+ E +C    L+H VL+VGYG +   ++ + YW++KNSW   WG NGY ++ ++  N C +A    YP V
Sbjct:   14 IASAVPKFDQNLDTKWYQWKATHRRLYGA-NEEGWRRAVWEKNMKMIELHNGEYSQGKHGFTMAMNAFGDMTNEEFRQMMGCFRNQKFRKGKVFREPLFLDLPKSVDWRKKGYVTPVKNQKQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQGNQGCNGGFMARAFQYVKENGGLDSEESYPYVAVDEI-----CKYRPENSVANDTGFTVVAPGKEKALMKAVATVGPISVAMDAGHSSFQFYKSGIYFEPDCSSKNLDHGVLVVGYGFEGANSNNSKYWLVKNSWGPEWGSNGYVKIAKDKNNHCGIATAASYPNV 334          
BLAST of Cathepsin L vs. Ensembl Human
Match: CTSL (cathepsin L [Source:HGNC Symbol;Acc:HGNC:2537])

HSP 1 Score: 211.46 bits (537), Expect = 3.607e-65
Identity = 124/315 (39.37%), Postives = 178/315 (56.51%), Query Frame = 2
Query:  143 DGEFQTFKQRYNKSYSSMHEENSRFLNFISSLLEINHHNQLYENGQKSYEIGINHLSDWSGEELAQ-LTKLKQSNLTGSSYLSSNVKIDLPDSFDWREKGAVTEVKNQGFCGSCYAFATTGTLEAQIWRKTGKLISLSEQQIVXXXXXXXXX--XXXFVQDALSYIKSNGGIENEESYPYISSETFKPNSKCNFFKSKVVATDTGFVQMPANDETKMKEALVTIGPISVAISAT-KSLKRYTSGIFHEDECDKLKLNHAVLIVGYGTDQT--SGTPYWIIKNSWSSFWGENGYFRLPRN-INACKVAMMPVYPLV 1066
            + ++  +K  +N+ Y  M+EE  R   +  ++  I  HNQ Y  G+ S+ + +N   D + EE  Q +   +             +  + P S DWREKG VT VKNQG CGSC+AF+ TG LE Q++RKTG+LISLSEQ +VDC         +GG +  A  Y++ NGG+++EESYPY ++E       C +     VA DTGFV +P  ++  MK A+ T+GPISVAI A  +S   Y  GI+ E +C    ++H VL+VGYG + T      YW++KNSW   WG  GY ++ ++  N C +A    YP V
Sbjct:   26 EAQWTKWKAMHNRLYG-MNEEGWRRAVWEKNMKMIELHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATE-----ESCKYNPKYSVANDTGFVDIPKQEKALMK-AVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV 333          
BLAST of Cathepsin L vs. Ensembl Human
Match: CTSL (cathepsin L [Source:HGNC Symbol;Acc:HGNC:2537])

HSP 1 Score: 211.46 bits (537), Expect = 3.607e-65
Identity = 124/315 (39.37%), Postives = 178/315 (56.51%), Query Frame = 2
Query:  143 DGEFQTFKQRYNKSYSSMHEENSRFLNFISSLLEINHHNQLYENGQKSYEIGINHLSDWSGEELAQ-LTKLKQSNLTGSSYLSSNVKIDLPDSFDWREKGAVTEVKNQGFCGSCYAFATTGTLEAQIWRKTGKLISLSEQQIVXXXXXXXXX--XXXFVQDALSYIKSNGGIENEESYPYISSETFKPNSKCNFFKSKVVATDTGFVQMPANDETKMKEALVTIGPISVAISAT-KSLKRYTSGIFHEDECDKLKLNHAVLIVGYGTDQT--SGTPYWIIKNSWSSFWGENGYFRLPRN-INACKVAMMPVYPLV 1066
            + ++  +K  +N+ Y  M+EE  R   +  ++  I  HNQ Y  G+ S+ + +N   D + EE  Q +   +             +  + P S DWREKG VT VKNQG CGSC+AF+ TG LE Q++RKTG+LISLSEQ +VDC         +GG +  A  Y++ NGG+++EESYPY ++E       C +     VA DTGFV +P  ++  MK A+ T+GPISVAI A  +S   Y  GI+ E +C    ++H VL+VGYG + T      YW++KNSW   WG  GY ++ ++  N C +A    YP V
Sbjct:   26 EAQWTKWKAMHNRLYG-MNEEGWRRAVWEKNMKMIELHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATE-----ESCKYNPKYSVANDTGFVDIPKQEKALMK-AVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV 333          
BLAST of Cathepsin L vs. Ensembl Human
Match: CTSS (cathepsin S [Source:HGNC Symbol;Acc:HGNC:2545])

HSP 1 Score: 208.764 bits (530), Expect = 3.283e-64
Identity = 132/319 (41.38%), Postives = 183/319 (57.37%), Query Frame = 2
Query:  143 DGEFQTFKQRYNKSYSSMHEENSRFLNFISSLLEINHHNQLYENGQKSYEIGINHLSDWSGEELAQL-TKLK-----QSNLTGSSYLSSNVKIDLPDSFDWREKGAVTEVKNQGFCGSCYAFATTGTLEAQIWRKTGKLISLSEQQIVXXXXXX---XXXXXXFVQDALSYIKSNGGIENEESYPYISSETFKPNSKCNFFKSKVVATDTGFVQMPANDETKMKEALVTIGPISVAISATK-SLKRYTSGIFHEDECDKLKLNHAVLIVGYGTDQTSGTPYWIIKNSWSSFWGENGYFRLPRNI-NACKVAMMPVYPLV 1066
            D  +  +K+ Y K Y   +EE  R L +  +L  +  HN  +  G  SY++G+NHL D + EE+  L + L+     Q N+T      SN    LPDS DWREKG VTEVK QG CG+C+AF+  G LEAQ+  KTGKL+SLS Q +VDC T      GC+GGF+  A  YI  N GI+++ SYPY + +      KC +      AT + + ++P   E  +KEA+   GP+SV + A   S   Y SG+++E  C +  +NH VL+VGYG    +G  YW++KNSW   +GE GY R+ RN  N C +A  P YP +
Sbjct:   25 DHHWHLWKKTYGKQYKEKNEEAVRRLIWEKNLKFVMLHNLEHSMGMHSYDLGMNHLGDMTSEEVMSLMSSLRVPSQWQRNIT----YKSNPNRILPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMD-----QKCQYDSKYRAATCSKYTELPYGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQ-NVNHGVLVVGYG--DLNGKEYWLVKNSWGHNFGEEGYIRMARNKGNHCGIASFPSYPEI 331          
BLAST of Cathepsin L vs. Ensembl Celegans
Match: cpl-1 (CathePsin L family [Source:UniProtKB/TrEMBL;Acc:H9G333])

HSP 1 Score: 242.276 bits (617), Expect = 1.488e-77
Identity = 131/314 (41.72%), Postives = 192/314 (61.15%), Query Frame = 2
Query:  149 EFQTFKQRYNKSYSSMHEENSRFLNFISSLLEINHHNQLYENGQKSYEIGINHLSDWSGEELAQLTKLKQ----SNLTGSSYLSSNVKIDLPDSFDWREKGAVTEVKNQGFCGSCYAFATTGTLEAQIWRKTGKLISLSEQQIVXXXXXXXXX--XXXFVQDALSYIKSNGGIENEESYPYISSETFKPNSKCNFFKSKVVATDTGFVQMPANDETKMKEALVTIGPISVAISAT-KSLKRYTSGIFHEDECDKLKLNHAVLIVGYGTDQTSGTPYWIIKNSWSSFWGENGYFRLPRNI-NACKVAMMPVYPLV 1066
            ++  +K+ ++K YS   EE +    F+ +++ I +HN+ +  G+K++E+G+NH++D    +  +L   ++    S +  SS   +   + +PD  DWR+   VT+VKNQG CGSC+AF+ TG LE Q  RK G+L+SLSEQ +VDC T       +GG +  A  YI+ N G++ EESYPY   +      KC+F K  V A D G+V  P  DE ++K A+ T GPIS+AI A  +S + Y  G+++++EC   +L+H VL+VGYGTD   G  YWI+KNSW + WGE GY R+ RN  N C VA    YPLV
Sbjct:   31 KWDDYKEDFDKEYSES-EEQTYMEAFVKNMIHIENHNRDHRLGRKTFEMGLNHIADLPFSQYRKLNGYRRLFGDSRIKNSSSFLAPFNVQVPDEVDWRDTHLVTDVKNQGMCGSCWAFSATGALEGQHARKLGQLVSLSEQNLVDCSTKYGNHGCNGGLMDQAFEYIRDNHGVDTEESYPYKGRDM-----KCHFNKKTVGADDKGYVDTPEGDEEQLKIAVATQGPISIAIDAGHRSFQLYKKGVYYDEECSSEELDHGVLLVGYGTDPEHGD-YWIVKNSWGAGWGEKGYIRIARNRNNHCGVATKASYPLV 337          
BLAST of Cathepsin L vs. Ensembl Celegans
Match: tag-196 (pep chromosome:WBcel235:V:8594914:8597500:1 gene:WBGene00007055.1 transcript:F41E6.6.2 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:tag-196)

HSP 1 Score: 191.43 bits (485), Expect = 1.998e-56
Identity = 127/315 (40.32%), Postives = 176/315 (55.87%), Query Frame = 2
Query:  152 FQTFKQRYNKSYSSMHEENSRFLNFISSLLEINHHNQLYENGQKSYEIGINHLSDWSGEELAQLTKLKQSN-----LTGSSYLSSNVKI---DLPDSFDWREKGAVTEVKNQGFCGSCYAFATTGTLEAQIWRKTGKLISLSEQQIVXXXXXXXXXXXXFVQDALSYIKSNGGIENEESYPYISSETFKPNSKCNFFKSKVVATDTGFVQMPANDETKMKEALVTIGPISVAISATKSLKRYTSGIFHEDE--CDKLKLNHAVLIVGYGTDQTSGTPYWIIKNSWSSFWGENGYFRLPRNINACKVAMMPVYPLV 1066
            F  F  R+ K Y++  E   RF  F  +   I    +L +N Q +   G    SD +  E  ++    Q       +  +++   +V I   DLP+SFDWREKGAVT+VKNQG CGSC+AF+TTG +E   +    KL+SLSEQ++VDCD+ D GC+GG   +A   I   GG+E E++YPY           C+  +  +     G V++P +DE +M++ LVT GPIS+ ++A  +L+ Y  G+ H  +  C+   LNH VLIVGYG D     PYWI+KNSW   WGE GYF+L R  N C V  M    LV
Sbjct:  174 FLDFVDRHEKKYTNKREVLKRFRVFKKNAKVIR---ELQKNEQGTAVYGFTKFSDMTTMEFKKIMLPYQWEQPVYPMEQANFEKHDVTINEEDLPESFDWREKGAVTQVKNQGNCGSCWAFSTTGNVEGAWFIAKNKLVSLSEQELVDCDSMDQGCNGGLPSNAYKEIIRMGGLEPEDAYPYDGR-----GETCHLVRKDIAVYINGSVELP-HDEVEMQKWLVTKGPISIGLNAN-TLQFYRHGVVHPFKIFCEPFMLNHGVLIVGYGKD--GRKPYWIVKNSWGPNWGEAGYFKLYRGKNVCGVQEMATSALV 476          
BLAST of Cathepsin L vs. Ensembl Celegans
Match: tag-196 (pep chromosome:WBcel235:V:8594914:8597469:1 gene:WBGene00007055.1 transcript:F41E6.6.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:tag-196)

HSP 1 Score: 191.43 bits (485), Expect = 1.998e-56
Identity = 127/315 (40.32%), Postives = 176/315 (55.87%), Query Frame = 2
Query:  152 FQTFKQRYNKSYSSMHEENSRFLNFISSLLEINHHNQLYENGQKSYEIGINHLSDWSGEELAQLTKLKQSN-----LTGSSYLSSNVKI---DLPDSFDWREKGAVTEVKNQGFCGSCYAFATTGTLEAQIWRKTGKLISLSEQQIVXXXXXXXXXXXXFVQDALSYIKSNGGIENEESYPYISSETFKPNSKCNFFKSKVVATDTGFVQMPANDETKMKEALVTIGPISVAISATKSLKRYTSGIFHEDE--CDKLKLNHAVLIVGYGTDQTSGTPYWIIKNSWSSFWGENGYFRLPRNINACKVAMMPVYPLV 1066
            F  F  R+ K Y++  E   RF  F  +   I    +L +N Q +   G    SD +  E  ++    Q       +  +++   +V I   DLP+SFDWREKGAVT+VKNQG CGSC+AF+TTG +E   +    KL+SLSEQ++VDCD+ D GC+GG   +A   I   GG+E E++YPY           C+  +  +     G V++P +DE +M++ LVT GPIS+ ++A  +L+ Y  G+ H  +  C+   LNH VLIVGYG D     PYWI+KNSW   WGE GYF+L R  N C V  M    LV
Sbjct:  174 FLDFVDRHEKKYTNKREVLKRFRVFKKNAKVIR---ELQKNEQGTAVYGFTKFSDMTTMEFKKIMLPYQWEQPVYPMEQANFEKHDVTINEEDLPESFDWREKGAVTQVKNQGNCGSCWAFSTTGNVEGAWFIAKNKLVSLSEQELVDCDSMDQGCNGGLPSNAYKEIIRMGGLEPEDAYPYDGR-----GETCHLVRKDIAVYINGSVELP-HDEVEMQKWLVTKGPISIGLNAN-TLQFYRHGVVHPFKIFCEPFMLNHGVLIVGYGKD--GRKPYWIVKNSWGPNWGEAGYFKLYRGKNVCGVQEMATSALV 476          
BLAST of Cathepsin L vs. Ensembl Celegans
Match: cpl-1 (CathePsin L family [Source:UniProtKB/TrEMBL;Acc:H9G333])

HSP 1 Score: 180.644 bits (457), Expect = 1.983e-55
Identity = 100/204 (49.02%), Postives = 131/204 (64.22%), Query Frame = 2
Query:  467 FCGSCYAFATTGTLEAQIWRKTGKLISLSEQQIVXXXXX--XXXXXXXFVQDALSYIKSNGGIENEESYPYISSETFKPNSKCNFFKSKVVATDTGFVQMPANDETKMKEALVTIGPISVAISAT-KSLKRYTSGIFHEDECDKLKLNHAVLIVGYGTDQTSGTPYWIIKNSWSSFWGENGYFRLPRNI-NACKVAMMPVYPLV 1066
             CGSC+AF+ TG LE Q  RK G+L+SLSEQ +VDC T   + GC+GG +  A  YI+ N G++ EESYPY   +      KC+F K  V A D G+V  P  DE ++K A+ T GPIS+AI A  +S + Y  G+++++EC   +L+H VL+VGYGTD   G  YWI+KNSW + WGE GY R+ RN  N C VA    YPLV
Sbjct:    1 MCGSCWAFSATGALEGQHARKLGQLVSLSEQNLVDCSTKYGNHGCNGGLMDQAFEYIRDNHGVDTEESYPYKGRDM-----KCHFNKKTVGADDKGYVDTPEGDEEQLKIAVATQGPISIAIDAGHRSFQLYKKGVYYDEECSSEELDHGVLLVGYGTDPEHGD-YWIVKNSWGAGWGEKGYIRIARNRNNHCGVATKASYPLV 198          
BLAST of Cathepsin L vs. Ensembl Celegans
Match: cpl-1 (CathePsin L family [Source:UniProtKB/TrEMBL;Acc:H9G333])

HSP 1 Score: 180.644 bits (457), Expect = 1.983e-55
Identity = 100/204 (49.02%), Postives = 131/204 (64.22%), Query Frame = 2
Query:  467 FCGSCYAFATTGTLEAQIWRKTGKLISLSEQQIVXXXXX--XXXXXXXFVQDALSYIKSNGGIENEESYPYISSETFKPNSKCNFFKSKVVATDTGFVQMPANDETKMKEALVTIGPISVAISAT-KSLKRYTSGIFHEDECDKLKLNHAVLIVGYGTDQTSGTPYWIIKNSWSSFWGENGYFRLPRNI-NACKVAMMPVYPLV 1066
             CGSC+AF+ TG LE Q  RK G+L+SLSEQ +VDC T   + GC+GG +  A  YI+ N G++ EESYPY   +      KC+F K  V A D G+V  P  DE ++K A+ T GPIS+AI A  +S + Y  G+++++EC   +L+H VL+VGYGTD   G  YWI+KNSW + WGE GY R+ RN  N C VA    YPLV
Sbjct:    1 MCGSCWAFSATGALEGQHARKLGQLVSLSEQNLVDCSTKYGNHGCNGGLMDQAFEYIRDNHGVDTEESYPYKGRDM-----KCHFNKKTVGADDKGYVDTPEGDEEQLKIAVATQGPISIAIDAGHRSFQLYKKGVYYDEECSSEELDHGVLLVGYGTDPEHGD-YWIVKNSWGAGWGEKGYIRIARNRNNHCGVATKASYPLV 198          
BLAST of Cathepsin L vs. Ensembl Fly
Match: Cp1 (gene:FBgn0013770 transcript:FBtr0087592)

HSP 1 Score: 246.128 bits (627), Expect = 6.870e-79
Identity = 136/321 (42.37%), Postives = 194/321 (60.44%), Query Frame = 2
Query:  149 EFQTFKQRYNKSYSSMHEENSRFLNFISSLLEINHHNQLYENGQKSYEIGINHLSDWSGEELAQLT-----------KLKQSNLTGSSYLSSNVKIDLPDSFDWREKGAVTEVKNQGFCGSCYAFATTGTLEAQIWRKTGKLISLSEQQIVXXXXXXXXX--XXXFVQDALSYIKSNGGIENEESYPYISSETFKPNSKCNFFKSKVVATDTGFVQMPANDETKMKEALVTIGPISVAISAT-KSLKRYTSGIFHEDECDKLKLNHAVLIVGYGTDQTSGTPYWIIKNSWSSFWGENGYFRLPRNI-NACKVAMMPVYPLV 1066
            E+ TFK  + K+Y    EE  R   F  +  +I  HNQ +  G+ S+++ +N  +D    E  QL            +    +  G +++S    + LP S DWR KGAVT VK+QG CGSC+AF++TG LE Q +RK+G L+SLSEQ +VDC T       +GG + +A  YIK NGGI+ E+SYPY +      +  C+F K  V ATD GF  +P  DE KM EA+ T+GP+SVAI A+ +S + Y+ G+++E +CD   L+H VL+VG+GTD+ SG  YW++KNSW + WG+ G+ ++ RN  N C +A    YPLV
Sbjct:   28 EWHTFKLEHRKNYQDETEERFRLKIFNENKHKIAKHNQRFAEGKVSFKLAVNKYADLLHHEFRQLMNGFNYTLHKQLRAADESFKGVTFISP-AHVTLPKSVDWRTKGAVTAVKDQGHCGSCWAFSSTGALEGQHFRKSGVLVSLSEQNLVDCSTKYGNNGCNGGLMDNAFRYIKDNGGIDTEKSYPYEA-----IDDSCHFNKGTVGATDRGFTDIPQGDEKKMAEAVATVGPVSVAIDASHESFQFYSEGVYNEPQCDAQNLDHGVLVVGFGTDE-SGEDYWLVKNSWGTTWGDKGFIKMLRNKENQCGIASASSYPLV 341          
BLAST of Cathepsin L vs. Ensembl Fly
Match: Cp1 (gene:FBgn0013770 transcript:FBtr0087593)

HSP 1 Score: 246.514 bits (628), Expect = 1.252e-78
Identity = 136/321 (42.37%), Postives = 194/321 (60.44%), Query Frame = 2
Query:  149 EFQTFKQRYNKSYSSMHEENSRFLNFISSLLEINHHNQLYENGQKSYEIGINHLSDWSGEELAQLT-----------KLKQSNLTGSSYLSSNVKIDLPDSFDWREKGAVTEVKNQGFCGSCYAFATTGTLEAQIWRKTGKLISLSEQQIVXXXXXXXXX--XXXFVQDALSYIKSNGGIENEESYPYISSETFKPNSKCNFFKSKVVATDTGFVQMPANDETKMKEALVTIGPISVAISAT-KSLKRYTSGIFHEDECDKLKLNHAVLIVGYGTDQTSGTPYWIIKNSWSSFWGENGYFRLPRNI-NACKVAMMPVYPLV 1066
            E+ TFK  + K+Y    EE  R   F  +  +I  HNQ +  G+ S+++ +N  +D    E  QL            +    +  G +++S    + LP S DWR KGAVT VK+QG CGSC+AF++TG LE Q +RK+G L+SLSEQ +VDC T       +GG + +A  YIK NGGI+ E+SYPY + +       C+F K  V ATD GF  +P  DE KM EA+ T+GP+SVAI A+ +S + Y+ G+++E +CD   L+H VL+VG+GTD+ SG  YW++KNSW + WG+ G+ ++ RN  N C +A    YPLV
Sbjct:   58 EWHTFKLEHRKNYQDETEERFRLKIFNENKHKIAKHNQRFAEGKVSFKLAVNKYADLLHHEFRQLMNGFNYTLHKQLRAADESFKGVTFISP-AHVTLPKSVDWRTKGAVTAVKDQGHCGSCWAFSSTGALEGQHFRKSGVLVSLSEQNLVDCSTKYGNNGCNGGLMDNAFRYIKDNGGIDTEKSYPYEAID-----DSCHFNKGTVGATDRGFTDIPQGDEKKMAEAVATVGPVSVAIDASHESFQFYSEGVYNEPQCDAQNLDHGVLVVGFGTDE-SGEDYWLVKNSWGTTWGDKGFIKMLRNKENQCGIASASSYPLV 371          
BLAST of Cathepsin L vs. Ensembl Fly
Match: Cp1 (gene:FBgn0013770 transcript:FBtr0339955)

HSP 1 Score: 239.195 bits (609), Expect = 2.569e-76
Identity = 137/329 (41.64%), Postives = 199/329 (60.49%), Query Frame = 2
Query:  134 SRYDGEFQTFKQ---RYNKSYSSMHEENSRFLNFISSLLEINHHNQLYENGQKSYEIGINHLSDWSGEELAQLT-----------KLKQSNLTGSSYLSSNVKIDLPDSFDWREKGAVTEVKNQGFCGSCYAFATTGTLEAQIWRKTGKLISLSEQQIVXXXXX--XXXXXXXFVQDALSYIKSNGGIENEESYPYISSETFKPNSKCNFFKSKVVATDTGFVQMPANDETKMKEALVTIGPISVAISAT-KSLKRYTSGIFHEDECDKLKLNHAVLIVGYGTDQTSGTPYWIIKNSWSSFWGENGYFRLPRNI-NACKVAMMPVYPLV 1066
            ++Y G  Q   +    + K+Y    EE  R   F  +  +I  HNQ +  G+ S+++ +N  +D    E  QL            +    +  G +++S    + LP S DWR KGAVT VK+QG CGSC+AF++TG LE Q +RK+G L+SLSEQ +VDC T   ++GC+GG + +A  YIK NGGI+ E+SYPY + +       C+F K  V ATD GF  +P  DE KM EA+ T+GP+SVAI A+ +S + Y+ G+++E +CD   L+H VL+VG+GTD+ SG  YW++KNSW + WG+ G+ ++ RN  N C +A    YPLV
Sbjct:   17 AKYPGILQNLLRLVLEHRKNYQDETEERFRLKIFNENKHKIAKHNQRFAEGKVSFKLAVNKYADLLHHEFRQLMNGFNYTLHKQLRAADESFKGVTFISP-AHVTLPKSVDWRTKGAVTAVKDQGHCGSCWAFSSTGALEGQHFRKSGVLVSLSEQNLVDCSTKYGNNGCNGGLMDNAFRYIKDNGGIDTEKSYPYEAID-----DSCHFNKGTVGATDRGFTDIPQGDEKKMAEAVATVGPVSVAIDASHESFQFYSEGVYNEPQCDAQNLDHGVLVVGFGTDE-SGEDYWLVKNSWGTTWGDKGFIKMLRNKENQCGIASASSYPLV 338          
BLAST of Cathepsin L vs. Ensembl Fly
Match: Cp1 (gene:FBgn0013770 transcript:FBtr0304021)

HSP 1 Score: 219.935 bits (559), Expect = 5.637e-70
Identity = 118/249 (47.39%), Postives = 167/249 (67.07%), Query Frame = 2
Query:  332 LAQLTKLKQSNLTGSSYLSSNVKIDLPDSFDWREKGAVTEVKNQGFCGSCYAFATTGTLEAQIWRKTGKLISLSEQQIVXXXXX--XXXXXXXFVQDALSYIKSNGGIENEESYPYISSETFKPNSKCNFFKSKVVATDTGFVQMPANDETKMKEALVTIGPISVAISAT-KSLKRYTSGIFHEDECDKLKLNHAVLIVGYGTDQTSGTPYWIIKNSWSSFWGENGYFRLPRNI-NACKVAMMPVYPLV 1066
            L +  +    +  G +++S    + LP S DWR KGAVT VK+QG CGSC+AF++TG LE Q +RK+G L+SLSEQ +VDC T   ++GC+GG + +A  YIK NGGI+ E+SYPY + +       C+F K  V ATD GF  +P  DE KM EA+ T+GP+SVAI A+ +S + Y+ G+++E +CD   L+H VL+VG+GTD+ SG  YW++KNSW + WG+ G+ ++ RN  N C +A    YPLV
Sbjct:    8 LHKQLRAADESFKGVTFISP-AHVTLPKSVDWRTKGAVTAVKDQGHCGSCWAFSSTGALEGQHFRKSGVLVSLSEQNLVDCSTKYGNNGCNGGLMDNAFRYIKDNGGIDTEKSYPYEAID-----DSCHFNKGTVGATDRGFTDIPQGDEKKMAEAVATVGPVSVAIDASHESFQFYSEGVYNEPQCDAQNLDHGVLVVGFGTDE-SGEDYWLVKNSWGTTWGDKGFIKMLRNKENQCGIASASSYPLV 249          
BLAST of Cathepsin L vs. Ensembl Fly
Match: CG4847 (gene:FBgn0034229 transcript:FBtr0086934)

HSP 1 Score: 217.238 bits (552), Expect = 4.422e-67
Identity = 131/326 (40.18%), Postives = 191/326 (58.59%), Query Frame = 2
Query:  122 VSLLSRYDGEFQTFKQRYNKSYSSMHEENSRFLNFISSLLEINHHNQLYENGQKSYEIGINHLSDWSGEE-LAQLTKLKQSNLTGSSYLSSNVKIDLP-----DSFDWREKGAVTEVKNQGFCGSCYAFATTGTLEAQIWRKTGKLISLSEQQIVXXXXXXX----XXXXXFVQDALSYIKS-NGGIENEESYPYISSETFKPNSKCNFFKSKVVATDTGFVQMPANDETKMKEALVTIGPISVAISATKSLKRYTSGIFHEDECDKLKLNHAVLIVGYGTDQTSGTPYWIIKNSWSSFWGENGYFRLPRNINACKVAMMPVYPLV 1066
            V LLS    +F  F  +  K+Y S  +       F S+   +   N  +  G  +++  +N  +D +  E L+QLT LK+S    +   +S   ++LP     D+FDWRE G VT VK QG CGSC+AFATTG +E   +RKTG L +LSEQ +VDC   +D    GCDGGF + A  +I     G+  E +YPYI ++       C +  SK  AT  GF  +P  DE ++K+ + T+GP++ +++  ++LK Y  GI+++DEC+K + NH++L+VGYG+++  G  YWI+KNSW   WGE GYFRLPR  N C +A    YP+V
Sbjct:   73 VPLLSNVQ-DFGDFLSQSGKTYLSAADRALHEGAFASTKNLVEAGNAAFAQGVHTFKQAVNAFADLTHSEFLSQLTGLKRSPEAKARAAASLKLVNLPAKPIPDAFDWREHGGVTPVKFQGTCGSCWAFATTGAIEGHTFRKTGSLPNLSEQNLVDCGPVEDFGLNGCDGGFQEAAFCFIDEVQKGVSQEGAYPYIDNK-----GTCKYDGSKSGATLQGFAAIPPKDEEQLKKVVATLGPVACSVNGLETLKNYAGGIYNDDECNKGEPNHSILVVGYGSEK--GQDYWIVKNSWDDTWGEKGYFRLPRGKNYCFIAEECSYPVV 390          
BLAST of Cathepsin L vs. Ensembl Zebrafish
Match: ctsl.1 (cathepsin L.1 [Source:ZFIN;Acc:ZDB-GENE-040718-61])

HSP 1 Score: 241.891 bits (616), Expect = 2.969e-77
Identity = 141/323 (43.65%), Postives = 202/323 (62.54%), Query Frame = 2
Query:  131 LSRYDGEFQTFKQRYNKSYSSMHEENSRFLNFISSLLEINHHNQLYENGQKSYEIGINHLSDWSGEELAQLT---KLKQSNLT----GSSYLSSNVKIDLPDSFDWREKGAVTEVKNQGFCGSCYAFATTGTLEAQIWRKTGKLISLSEQQIVXXXXXXX--XXXXXFVQDALSYIKSNGGIENEESYPYISSETFKPNSKCNFFKSKVVATDTGFVQMPANDETKMKEALVTIGPISVAISAT-KSLKRYTSGIFHEDECDKLKLNHAVLIVGYGTDQTSGTPYWIIKNSWSSFWGENGYFRLPRN-INACKVAMMPVYPLV 1066
            LS  D EF  +K ++ KSY S  EE+ R L ++++   +  HN + + G KSY +G+ + +D S EE  QL     L   N T    GS++        +PD+ DWR+KG VT++K+Q  CGSC+AF+ TG+LE Q +RKTGKL+SLSEQQ+VDC  +    GCDGG +  A  YI++N G++ E+SYPY + +      +C F  S V A+ TG+V + + DE+ ++EA+ TIGPISVAI A   S + Y+SG+++E +C   +L+H VL VGYG+  ++G  YWI+KNSW   WG  GY  + RN  N C +A    YPLV
Sbjct:   19 LSLEDMEFHAWKLKFGKSYRSAEEESHRQLTWLTNRKLVLVHNMMADQGLKSYRLGMTYFADMSNEEYRQLVFRGCLGSMNNTKARGGSTFFRLRKAAVVPDTVDWRDKGYVTDIKDQKQCGSCWAFSATGSLEGQTFRKTGKLVSLSEQQLVDCSGSYGNYGCDGGLMDQAFQYIEANKGLDTEDSYPYEAQD-----GECRFNPSTVGASCTGYVDIASGDESALQEAVATIGPISVAIDAGHSSFQLYSSGVYNEPDCSSSELDHGVLAVGYGS--SNGDDYWIVKNSWGLDWGVQGYILMSRNKSNQCGIATAASYPLV 334          
BLAST of Cathepsin L vs. Ensembl Zebrafish
Match: ctsl.1 (cathepsin L.1 [Source:ZFIN;Acc:ZDB-GENE-040718-61])

HSP 1 Score: 241.891 bits (616), Expect = 2.969e-77
Identity = 141/323 (43.65%), Postives = 202/323 (62.54%), Query Frame = 2
Query:  131 LSRYDGEFQTFKQRYNKSYSSMHEENSRFLNFISSLLEINHHNQLYENGQKSYEIGINHLSDWSGEELAQLT---KLKQSNLT----GSSYLSSNVKIDLPDSFDWREKGAVTEVKNQGFCGSCYAFATTGTLEAQIWRKTGKLISLSEQQIVXXXXXXX--XXXXXFVQDALSYIKSNGGIENEESYPYISSETFKPNSKCNFFKSKVVATDTGFVQMPANDETKMKEALVTIGPISVAISAT-KSLKRYTSGIFHEDECDKLKLNHAVLIVGYGTDQTSGTPYWIIKNSWSSFWGENGYFRLPRN-INACKVAMMPVYPLV 1066
            LS  D EF  +K ++ KSY S  EE+ R L ++++   +  HN + + G KSY +G+ + +D S EE  QL     L   N T    GS++        +PD+ DWR+KG VT++K+Q  CGSC+AF+ TG+LE Q +RKTGKL+SLSEQQ+VDC  +    GCDGG +  A  YI++N G++ E+SYPY + +      +C F  S V A+ TG+V + + DE+ ++EA+ TIGPISVAI A   S + Y+SG+++E +C   +L+H VL VGYG+  ++G  YWI+KNSW   WG  GY  + RN  N C +A    YPLV
Sbjct:   19 LSLEDMEFHAWKLKFGKSYRSAEEESHRQLTWLTNRKLVLVHNMMADQGLKSYRLGMTYFADMSNEEYRQLVFRGCLGSMNNTKARGGSTFFRLRKAAVVPDTVDWRDKGYVTDIKDQKQCGSCWAFSATGSLEGQTFRKTGKLVSLSEQQLVDCSGSYGNYGCDGGLMDQAFQYIEANKGLDTEDSYPYEAQD-----GECRFNPSTVGASCTGYVDIASGDESALQEAVATIGPISVAIDAGHSSFQLYSSGVYNEPDCSSSELDHGVLAVGYGS--SNGDDYWIVKNSWGLDWGVQGYILMSRNKSNQCGIATAASYPLV 334          
BLAST of Cathepsin L vs. Ensembl Zebrafish
Match: ctsl.1 (cathepsin L.1 [Source:ZFIN;Acc:ZDB-GENE-040718-61])

HSP 1 Score: 241.891 bits (616), Expect = 2.969e-77
Identity = 141/323 (43.65%), Postives = 202/323 (62.54%), Query Frame = 2
Query:  131 LSRYDGEFQTFKQRYNKSYSSMHEENSRFLNFISSLLEINHHNQLYENGQKSYEIGINHLSDWSGEELAQLT---KLKQSNLT----GSSYLSSNVKIDLPDSFDWREKGAVTEVKNQGFCGSCYAFATTGTLEAQIWRKTGKLISLSEQQIVXXXXXXX--XXXXXFVQDALSYIKSNGGIENEESYPYISSETFKPNSKCNFFKSKVVATDTGFVQMPANDETKMKEALVTIGPISVAISAT-KSLKRYTSGIFHEDECDKLKLNHAVLIVGYGTDQTSGTPYWIIKNSWSSFWGENGYFRLPRN-INACKVAMMPVYPLV 1066
            LS  D EF  +K ++ KSY S  EE+ R L ++++   +  HN + + G KSY +G+ + +D S EE  QL     L   N T    GS++        +PD+ DWR+KG VT++K+Q  CGSC+AF+ TG+LE Q +RKTGKL+SLSEQQ+VDC  +    GCDGG +  A  YI++N G++ E+SYPY + +      +C F  S V A+ TG+V + + DE+ ++EA+ TIGPISVAI A   S + Y+SG+++E +C   +L+H VL VGYG+  ++G  YWI+KNSW   WG  GY  + RN  N C +A    YPLV
Sbjct:   19 LSLEDMEFHAWKLKFGKSYRSAEEESHRQLTWLTNRKLVLVHNMMADQGLKSYRLGMTYFADMSNEEYRQLVFRGCLGSMNNTKARGGSTFFRLRKAAVVPDTVDWRDKGYVTDIKDQKQCGSCWAFSATGSLEGQTFRKTGKLVSLSEQQLVDCSGSYGNYGCDGGLMDQAFQYIEANKGLDTEDSYPYEAQD-----GECRFNPSTVGASCTGYVDIASGDESALQEAVATIGPISVAIDAGHSSFQLYSSGVYNEPDCSSSELDHGVLAVGYGS--SNGDDYWIVKNSWGLDWGVQGYILMSRNKSNQCGIATAASYPLV 334          
BLAST of Cathepsin L vs. Ensembl Zebrafish
Match: ctsla (cathepsin La [Source:ZFIN;Acc:ZDB-GENE-030131-106])

HSP 1 Score: 230.72 bits (587), Expect = 6.715e-73
Identity = 130/324 (40.12%), Postives = 193/324 (59.57%), Query Frame = 2
Query:  125 SLLSRYDGEFQTFKQRYNKSYSSMHEENSRFLNFISSLLEINHHNQLYENGQKSYEIGINHLSDWSGEELAQLTK----LKQSNLTGSSYLSSNVKIDLPDSFDWREKGAVTEVKNQGFCGSCYAFATTGTLEAQIWRKTGKLISLSEQQIVXXXXXXXXX--XXXFVQDALSYIKSNGGIENEESYPYISSETFKPNSKCNFFKSKVVATDTGFVQMPANDETKMKEALVTIGPISVAISAT-KSLKRYTSGIFHEDECDKLKLNHAVLIVGYG--TDQTSGTPYWIIKNSWSSFWGENGYFRLPRNI-NACKVAMMPVYPLV 1066
            +L  + +  +  +K+ ++K Y +  EE  R + +  +L +I  HN  +  G  +Y +G+NH  D + EE  Q+       K     GS ++  N  I++P+  DWREKG VT VK+QG CGSC+AF+TTG LE Q++RKTGKL+SLSEQ +VDC   +     +GG +  A  Y+K   G+++EESYPY+ ++    +  C+F      A DTGFV +P+  E  + +A+  +GP+SVAI A  +S + Y SGI++E EC   +L+H VL VGYG   +   G  YWI+KNSWS  WG+ GY  + ++  N C +A    YPLV
Sbjct:   20 TLDQQLNDHWDQWKKWHSKKYHAT-EEGWRRIIWEKNLKKIEMHNLEHSMGIHTYRLGMNHFGDMTHEEFRQVMNGFKHKKDRRFRGSLFMEPNF-IEVPNKLDWREKGYVTPVKDQGECGSCWAFSTTGALEGQMFRKTGKLVSLSEQNLVDCSRPEGNEGCNGGLMDQAFQYVKDQNGLDSEESYPYLGTD----DQPCHFDPKNSAANDTGFVDIPSGKERALMKAIAAVGPVSVAIDAGHESFQFYQSGIYYEKECSSEELDHGVLAVGYGFEGEDVDGKKYWIVKNSWSENWGDKGYIYMAKDRHNHCGIATAASYPLV 337          
BLAST of Cathepsin L vs. Ensembl Zebrafish
Match: ctsla (cathepsin La [Source:ZFIN;Acc:ZDB-GENE-030131-106])

HSP 1 Score: 230.72 bits (587), Expect = 6.715e-73
Identity = 130/324 (40.12%), Postives = 193/324 (59.57%), Query Frame = 2
Query:  125 SLLSRYDGEFQTFKQRYNKSYSSMHEENSRFLNFISSLLEINHHNQLYENGQKSYEIGINHLSDWSGEELAQLTK----LKQSNLTGSSYLSSNVKIDLPDSFDWREKGAVTEVKNQGFCGSCYAFATTGTLEAQIWRKTGKLISLSEQQIVXXXXXXXXX--XXXFVQDALSYIKSNGGIENEESYPYISSETFKPNSKCNFFKSKVVATDTGFVQMPANDETKMKEALVTIGPISVAISAT-KSLKRYTSGIFHEDECDKLKLNHAVLIVGYG--TDQTSGTPYWIIKNSWSSFWGENGYFRLPRNI-NACKVAMMPVYPLV 1066
            +L  + +  +  +K+ ++K Y +  EE  R + +  +L +I  HN  +  G  +Y +G+NH  D + EE  Q+       K     GS ++  N  I++P+  DWREKG VT VK+QG CGSC+AF+TTG LE Q++RKTGKL+SLSEQ +VDC   +     +GG +  A  Y+K   G+++EESYPY+ ++    +  C+F      A DTGFV +P+  E  + +A+  +GP+SVAI A  +S + Y SGI++E EC   +L+H VL VGYG   +   G  YWI+KNSWS  WG+ GY  + ++  N C +A    YPLV
Sbjct:   20 TLDQQLNDHWDQWKKWHSKKYHAT-EEGWRRIIWEKNLKKIEMHNLEHSMGIHTYRLGMNHFGDMTHEEFRQVMNGFKHKKDRRFRGSLFMEPNF-IEVPNKLDWREKGYVTPVKDQGECGSCWAFSTTGALEGQMFRKTGKLVSLSEQNLVDCSRPEGNEGCNGGLMDQAFQYVKDQNGLDSEESYPYLGTD----DQPCHFDPKNSAANDTGFVDIPSGKERALMKAIAAVGPVSVAIDAGHESFQFYQSGIYYEKECSSEELDHGVLAVGYGFEGEDVDGKKYWIVKNSWSENWGDKGYIYMAKDRHNHCGIATAASYPLV 337          
BLAST of Cathepsin L vs. Ensembl Xenopus
Match: fcrl2 (Fc receptor-like 2 [Source:Xenbase;Acc:XB-GENE-5904272])

HSP 1 Score: 225.713 bits (574), Expect = 9.580e-71
Identity = 131/316 (41.46%), Postives = 188/316 (59.49%), Query Frame = 2
Query:  143 DGEFQTFKQRYNKSYSSMHEENSRFLNFISSLLEINHHNQLYENGQKSYEIGINHLSDWSGEELAQLTK--LKQSNLTGSSYLSSNVKIDLPDSFDWREKGAVTEVKNQGFCGSCYAFATTGTLEAQIWRKTGKLISLSEQQIVXXXXXXXXX--XXXFVQDALSYIKSNGGIENEESYPYISSETFKPNSKCNFFKSKVVATDTGFVQMPANDETKMKEALVTIGPISVAISAT-KSLKRYTSGIFHEDECDKLKLNHAVLIVGYG--TDQTSGTPYWIIKNSWSSFWGENGYFRLPRNI-NACKVAMMPVYPLV 1066
            D  +  +K  + KSY+   EE  R + +  +L  I  HN  +  G+ S+ +G+N   D + EE  QL      Q  + GS++L+ N   + P S DWR+KG VT VK+QG CGSC+AF+TTG LE Q +R TGK+ISLSEQ +VDC         +GG +  A  Y+K NGGI++E+SYPY    T K + +C++  +   A DTGFV + +  E  +  A+ ++GP+SVA+ A  +S + Y SGI++E EC    L+H VL+VGYG   +   G  YWI+KNSWS  WG +GY  + ++  N C +A    YPLV
Sbjct:   26 DNHWNLWKNWHKKSYAPK-EEGWRRVLWEKNLRMIEFHNLEHSLGKHSHSLGMNQFGDMTNEEFRQLMNGYKNQKKIRGSTFLAPN-NFESPKSVDWRKKGYVTPVKDQGQCGSCWAFSTTGALEGQHYRNTGKMISLSEQNLVDCSRAQGNQGCNGGLMDQAFQYVKDNGGIDSEDSYPY----TAKDDQECHYDPNYNSANDTGFVDVTSGSEKDLMNAVASVGPVSVAVDAGHQSFQFYKSGIYYEPECSSEDLDHGVLVVGYGFEGEDEDGKKYWIVKNSWSEKWGNDGYIYIAKDRHNHCGIATAASYPLV 335          
BLAST of Cathepsin L vs. Ensembl Xenopus
Match: fcrl2 (Fc receptor-like 2 [Source:Xenbase;Acc:XB-GENE-5904272])

HSP 1 Score: 225.713 bits (574), Expect = 1.138e-70
Identity = 131/316 (41.46%), Postives = 188/316 (59.49%), Query Frame = 2
Query:  143 DGEFQTFKQRYNKSYSSMHEENSRFLNFISSLLEINHHNQLYENGQKSYEIGINHLSDWSGEELAQLTK--LKQSNLTGSSYLSSNVKIDLPDSFDWREKGAVTEVKNQGFCGSCYAFATTGTLEAQIWRKTGKLISLSEQQIVXXXXXXXXX--XXXFVQDALSYIKSNGGIENEESYPYISSETFKPNSKCNFFKSKVVATDTGFVQMPANDETKMKEALVTIGPISVAISAT-KSLKRYTSGIFHEDECDKLKLNHAVLIVGYG--TDQTSGTPYWIIKNSWSSFWGENGYFRLPRNI-NACKVAMMPVYPLV 1066
            D  +  +K  + KSY+   EE  R + +  +L  I  HN  +  G+ S+ +G+N   D + EE  QL      Q  + GS++L+ N   + P S DWR+KG VT VK+QG CGSC+AF+TTG LE Q +R TGK+ISLSEQ +VDC         +GG +  A  Y+K NGGI++E+SYPY    T K + +C++  +   A DTGFV + +  E  +  A+ ++GP+SVA+ A  +S + Y SGI++E EC    L+H VL+VGYG   +   G  YWI+KNSWS  WG +GY  + ++  N C +A    YPLV
Sbjct:   33 DNHWNLWKNWHKKSYAPK-EEGWRRVLWEKNLRMIEFHNLEHSLGKHSHSLGMNQFGDMTNEEFRQLMNGYKNQKKIRGSTFLAPN-NFESPKSVDWRKKGYVTPVKDQGQCGSCWAFSTTGALEGQHYRNTGKMISLSEQNLVDCSRAQGNQGCNGGLMDQAFQYVKDNGGIDSEDSYPY----TAKDDQECHYDPNYNSANDTGFVDVTSGSEKDLMNAVASVGPVSVAVDAGHQSFQFYKSGIYYEPECSSEDLDHGVLVVGYGFEGEDEDGKKYWIVKNSWSEKWGNDGYIYIAKDRHNHCGIATAASYPLV 342          
BLAST of Cathepsin L vs. Ensembl Xenopus
Match: ctsk (cathepsin K (pycnodysostosis) [Source:NCBI gene;Acc:448216])

HSP 1 Score: 214.157 bits (544), Expect = 2.360e-66
Identity = 118/317 (37.22%), Postives = 199/317 (62.78%), Query Frame = 2
Query:  134 SRYDGEFQTFKQRYNKSYSSMHEENSRFLNFISSLLEINHHNQLYENGQKSYEIGINHLSDWSGEELAQLT---KLKQSNLTGSSYLSS-NVKIDLPDSFDWREKGAVTEVKNQGFCGSCYAFATTGTLEAQIWRKTGKLISLSEQQIVXXXXXXXXXXXXFVQDALSYIKSNGGIENEESYPYISSETFKPNSKCNFFKSKVVATDTGFVQMPANDETKMKEALVTIGPISVAISAT-KSLKRYTSGIFHEDECDKLKLNHAVLIVGYGTDQTSGTPYWIIKNSWSSFWGENGYFRLPRN-INACKVAMMPVYPLV 1066
            S  D +++ +K+ Y++ Y+   +E  R   +  +L  I+ HN+ +  G  +Y++ +NHL D + EE+ Q     K+  ++   ++Y+   N +I  P+  D+R+KG VT V NQG CGSC+AF++ G LE Q+ +KTGKL+SLS Q +VDCDT++ GC+GG++ +A  Y++ NGGI+++  YPY+  +       C++  +   AT  G+ ++P   E  +K A+  +GP+SV+I A+  S + Y  G++++  C+   +NHAVL+VGYG ++  G  +WIIKNSW  +WG+ GY  L R+  NAC +A +  +P++
Sbjct:   22 SNLDSKWELWKKTYHRQYNGQLDEIRRRQIWEKNLNLISQHNKEFSQGLHTYDLAMNHLGDMTSEEVVQKMMGLKVPPNHRPNNTYIPEWNSRI--PEYIDYRKKGYVTPVHNQGICGSCWAFSSVGALEGQLMKKTGKLVSLSPQNLVDCDTDNYGCEGGYMTNAFGYVRDNGGIDSDAEYPYVGQD-----EGCHYNPADKAATCKGYKEIPVGSEKALKRAVANVGPVSVSIDASLPSFQFYKKGVYYDSSCNPDAVNHAVLVVGYGNEK--GIKHWIIKNSWGDWWGKKGYVLLARDKKNACGIASLASFPVM 329          
BLAST of Cathepsin L vs. Ensembl Xenopus
Match: ctsk (cathepsin K (pycnodysostosis) [Source:NCBI gene;Acc:448216])

HSP 1 Score: 214.157 bits (544), Expect = 2.763e-66
Identity = 118/317 (37.22%), Postives = 199/317 (62.78%), Query Frame = 2
Query:  134 SRYDGEFQTFKQRYNKSYSSMHEENSRFLNFISSLLEINHHNQLYENGQKSYEIGINHLSDWSGEELAQLT---KLKQSNLTGSSYLSS-NVKIDLPDSFDWREKGAVTEVKNQGFCGSCYAFATTGTLEAQIWRKTGKLISLSEQQIVXXXXXXXXXXXXFVQDALSYIKSNGGIENEESYPYISSETFKPNSKCNFFKSKVVATDTGFVQMPANDETKMKEALVTIGPISVAISAT-KSLKRYTSGIFHEDECDKLKLNHAVLIVGYGTDQTSGTPYWIIKNSWSSFWGENGYFRLPRN-INACKVAMMPVYPLV 1066
            S  D +++ +K+ Y++ Y+   +E  R   +  +L  I+ HN+ +  G  +Y++ +NHL D + EE+ Q     K+  ++   ++Y+   N +I  P+  D+R+KG VT V NQG CGSC+AF++ G LE Q+ +KTGKL+SLS Q +VDCDT++ GC+GG++ +A  Y++ NGGI+++  YPY+  +       C++  +   AT  G+ ++P   E  +K A+  +GP+SV+I A+  S + Y  G++++  C+   +NHAVL+VGYG ++  G  +WIIKNSW  +WG+ GY  L R+  NAC +A +  +P++
Sbjct:   29 SNLDSKWELWKKTYHRQYNGQLDEIRRRQIWEKNLNLISQHNKEFSQGLHTYDLAMNHLGDMTSEEVVQKMMGLKVPPNHRPNNTYIPEWNSRI--PEYIDYRKKGYVTPVHNQGICGSCWAFSSVGALEGQLMKKTGKLVSLSPQNLVDCDTDNYGCEGGYMTNAFGYVRDNGGIDSDAEYPYVGQD-----EGCHYNPADKAATCKGYKEIPVGSEKALKRAVANVGPVSVSIDASLPSFQFYKKGVYYDSSCNPDAVNHAVLVVGYGNEK--GIKHWIIKNSWGDWWGKKGYVLLARDKKNACGIASLASFPVM 336          
BLAST of Cathepsin L vs. Ensembl Xenopus
Match: harbi1 (harbinger transposase derived 1 [Source:Xenbase;Acc:XB-GENE-6077433])

HSP 1 Score: 208.764 bits (530), Expect = 3.074e-64
Identity = 123/314 (39.17%), Postives = 183/314 (58.28%), Query Frame = 2
Query:  143 DGEFQTFKQRYNKSYSSMHEENSRFLNFISSLLEINHHNQLYENGQKSYEIGINHLSDWSGEELAQL-TKLKQSNLTGSSYLSSN---VKIDLPDSFDWREKGAVTEVKNQGFCGSCYAFATTGTLEAQIWRKTGKLISLSEQQIVXXXXXXXXXXXXFVQDALSYIKSNGGIENEESYPYISSETFKPNSKCNFFKSKVVATDTGFVQMPANDETKMKEALVTIGPISVAISAT-KSLKRYTSGIFHEDECDKLKLNHAVLIVGYGTDQTSGTPYWIIKNSWSSFWGENGYFRLPRNI-NACKVAMMPVYPLV 1066
            D E++ +K  Y+K Y +   E  R L +  +L  I  HN  +  G  +YE+G+N   D + EE+ ++ T LK     G + L+S+       +P+S D+R+KG VT +++QG CGSC+AF+T G LE Q+ +KTGKL+ +S Q +VDC  ++ GC GG++  A  Y+K N GI++EE+YPY+  +      KC +  S   A   GF ++    ET +K+A+  +GPISV I A   +   Y  GI+++  CD   +NHAVL VGYG  +     YWIIKNSW   WG  GY  + R   NAC +A +  YP++
Sbjct:   25 DSEWEIWKTTYHKHYDNKIHELMRRLIWEKNLNIIRSHNLEFTQGLHTYELGMNKFGDMTSEEVVRMMTGLKVHTGMGPTNLTSDEDEASQRIPNSIDYRKKGYVTPIRDQGECGSCWAFSTVGALEGQLMKKTGKLVGISPQNLVDCVKDNFGCGGGYMTTAFKYVKKNKGIDSEEAYPYVGMD-----QKCKYNVSGRAAEIKGFKEVKKGSETALKKAVGLVGPISVGIDAGLDTFFLYKKGIYYDKSCDGDSINHAVLAVGYGKQKKG--KYWIIKNSWGEDWGNKGYILMAREKGNACGIANLASYPVM 331          
BLAST of Cathepsin L vs. Ensembl Mouse
Match: Ctsk (cathepsin K [Source:MGI Symbol;Acc:MGI:107823])

HSP 1 Score: 223.787 bits (569), Expect = 3.597e-70
Identity = 130/330 (39.39%), Postives = 202/330 (61.21%), Query Frame = 2
Query:  101 KFELENMVSLL----SRYDGEFQTFKQRYNKSYSSMHEENSRFLNFISSLLEINHHNQLYENGQKSYEIGINHLSDWSGEELAQ-LTKLK---QSNLTGSSYLSSNVKIDLPDSFDWREKGAVTEVKNQGFCGSCYAFATTGTLEAQIWRKTGKLISLSEQQIVXXXXXXXXXXXXFVQDALSYIKSNGGIENEESYPYISSETFKPNSKCNFFKSKVVATDTGFVQMPANDETKMKEALVTIGPISVAISAT-KSLKRYTSGIFHEDECDKLKLNHAVLIVGYGTDQTSGTPYWIIKNSWSSFWGENGYFRLPRNI-NACKVAMMPVYP 1060
            KF L  MVS         D +++ +K+ + K Y+S  +E SR L +  +L +I+ HN     G  +YE+ +NHL D + EE+ Q +T L+     + +  +  +   +  +PDS D+R+KG VT VKNQG CGSC+AF++ G LE Q+ +KTGKL++LS Q +VDC T + GC GG++  A  Y++ NGGI++E++YPY+  +       C +  +   A   G+ ++P  +E  +K A+  +GPISV+I A+  S + Y+ G+++++ CD+  +NHAVL+VGYGT +  G+ +WIIKNSW   WG  GY  L RN  NAC +  M  +P
Sbjct:    5 KFLLLPMVSFALSPEEMLDTQWELWKKTHQKQYNSKVDEISRRLIWEKNLKQISAHNLEASLGVHTYELAMNHLGDMTSEEVVQKMTGLRIPPSRSYSNDTLYTPEWEGRVPDSIDYRKKGYVTPVKNQGQCGSCWAFSSAGALEGQLKKKTGKLLALSPQNLVDCVTENYGCGGGYMTTAFQYVQQNGGIDSEDAYPYVGQD-----ESCMYNATAKAAKCRGYREIPVGNEKALKRAVARVGPISVSIDASLASFQFYSRGVYYDENCDRDNVNHAVLVVGYGTQK--GSKHWIIKNSWGESWGNKGYALLARNKNNACGITNMASFP 327          
BLAST of Cathepsin L vs. Ensembl Mouse
Match: Ctsl (cathepsin L [Source:MGI Symbol;Acc:MGI:88564])

HSP 1 Score: 216.853 bits (551), Expect = 2.024e-67
Identity = 126/316 (39.87%), Postives = 182/316 (57.59%), Query Frame = 2
Query:  140 YDGEFQTFKQRYNKSYSSMHEENSRFLNFISSLLEINHHNQLYENGQKSYEIGINHLSDWSGEELAQLTK-LKQSNLTGSSYLSSNVKIDLPDSFDWREKGAVTEVKNQGFCGSCYAFATTGTLEAQIWRKTGKLISLSEQQIV--XXXXXXXXXXXXFVQDALSYIKSNGGIENEESYPYISSETFKPNSKCNFFKSKVVATDTGFVQMPANDETKMKEALVTIGPISVAISATK-SLKRYTSGIFHEDECDKLKLNHAVLIVGYGTDQTSG--TPYWIIKNSWSSFWGENGYFRLPRNI-NACKVAMMPVYPLV 1066
            +  E+  +K  + + Y +  EE  R + +  ++  I  HN  Y NGQ  + + +N   D + EE  Q+    +             + + +P S DWREKG VT VKNQG CGSC+AF+ +G LE Q++ KTGKLISLSEQ +V       + GC+GG +  A  YIK NGG+++EESYPY + +       C +     VA DTGFV +P  ++  MK A+ T+GPISVA+ A+  SL+ Y+SGI++E  C    L+H VL+VGYG + T      YW++KNSW S WG  GY ++ ++  N C +A    YP+V
Sbjct:   25 FSAEWHQWKSTHRRLYGTNEEEWRRAI-WEKNMRMIQLHNGEYSNGQHGFSMEMNAFGDMTNEEFRQVVNGYRHQKHKKGRLFQEPLMLKIPKSVDWREKGCVTPVKNQGQCGSCWAFSASGCLEGQMFLKTGKLISLSEQNLVDCSHAQGNQGCNGGLMDFAFQYIKENGGLDSEESYPYEAKD-----GSCKYRAEFAVANDTGFVDIPQQEKALMK-AVATVGPISVAMDASHPSLQFYSSGIYYEPNCSSKNLDHGVLLVGYGYEGTDSNKNKYWLVKNSWGSEWGMEGYIKIAKDRDNHCGLATAASYPVV 333          
BLAST of Cathepsin L vs. Ensembl Mouse
Match: Ctsl (cathepsin L [Source:MGI Symbol;Acc:MGI:88564])

HSP 1 Score: 216.853 bits (551), Expect = 2.024e-67
Identity = 126/316 (39.87%), Postives = 182/316 (57.59%), Query Frame = 2
Query:  140 YDGEFQTFKQRYNKSYSSMHEENSRFLNFISSLLEINHHNQLYENGQKSYEIGINHLSDWSGEELAQLTK-LKQSNLTGSSYLSSNVKIDLPDSFDWREKGAVTEVKNQGFCGSCYAFATTGTLEAQIWRKTGKLISLSEQQIV--XXXXXXXXXXXXFVQDALSYIKSNGGIENEESYPYISSETFKPNSKCNFFKSKVVATDTGFVQMPANDETKMKEALVTIGPISVAISATK-SLKRYTSGIFHEDECDKLKLNHAVLIVGYGTDQTSG--TPYWIIKNSWSSFWGENGYFRLPRNI-NACKVAMMPVYPLV 1066
            +  E+  +K  + + Y +  EE  R + +  ++  I  HN  Y NGQ  + + +N   D + EE  Q+    +             + + +P S DWREKG VT VKNQG CGSC+AF+ +G LE Q++ KTGKLISLSEQ +V       + GC+GG +  A  YIK NGG+++EESYPY + +       C +     VA DTGFV +P  ++  MK A+ T+GPISVA+ A+  SL+ Y+SGI++E  C    L+H VL+VGYG + T      YW++KNSW S WG  GY ++ ++  N C +A    YP+V
Sbjct:   25 FSAEWHQWKSTHRRLYGTNEEEWRRAI-WEKNMRMIQLHNGEYSNGQHGFSMEMNAFGDMTNEEFRQVVNGYRHQKHKKGRLFQEPLMLKIPKSVDWREKGCVTPVKNQGQCGSCWAFSASGCLEGQMFLKTGKLISLSEQNLVDCSHAQGNQGCNGGLMDFAFQYIKENGGLDSEESYPYEAKD-----GSCKYRAEFAVANDTGFVDIPQQEKALMK-AVATVGPISVAMDASHPSLQFYSSGIYYEPNCSSKNLDHGVLLVGYGYEGTDSNKNKYWLVKNSWGSEWGMEGYIKIAKDRDNHCGLATAASYPVV 333          
BLAST of Cathepsin L vs. Ensembl Mouse
Match: 4930486L24Rik (RIKEN cDNA 4930486L24 gene [Source:MGI Symbol;Acc:MGI:1922258])

HSP 1 Score: 209.92 bits (533), Expect = 8.982e-65
Identity = 115/315 (36.51%), Postives = 181/315 (57.46%), Query Frame = 2
Query:  143 DGEFQTFKQRYNKSYSSMHEENSRFLNFISSLLEINHHNQLYENGQKSYEIGINHLSDWSGEELAQL-TKLKQSNLTGSSYLSSNVKIDLPDSFDWREKGAVTEVKNQGFCGSCYAFATTGTLEAQIWRKTGKLISLSEQQIV--XXXXXXXXXXXXFVQDALSYIKSNGGIENEESYPYISSETFKPNSKCNFFKSKVVATDTGFVQMPANDETKMKEALVTIGPISVAISAT-KSLKRYTSGIFHEDECDKLKLNHAVLIVGYG--TDQTSGTPYWIIKNSWSSFWGENGYFRLPRNI-NACKVAMMPVYPLV 1066
            D ++  ++ ++ K+Y+ ++EE  R   +  +   I  HN  Y  G+  + + +N   D +  E  ++ T  ++  +        +  + +P   DWR  G VT VKNQG+C S +AF+ TG+LE Q+++KTG+L+ LSEQ ++          C GGF+Q+A  Y+K NGG+  EESYPYI      P  KC +      A    FVQ+P  +E  MK A+  +GPISVA+ A+  S + Y SGI++E +C ++ LNHAVL+VGYG   +++ G  YW++KNSW   WG  GY ++ ++  N C +A +  YP+V
Sbjct:   26 DVQWNEWRTKHGKAYN-VNEERLRRAVWEKNFKMIELHNWEYLEGKHDFTMTMNAFGDLTNTEFVKMMTGFRRQKIKRMHVFQDHQFLYVPKYVDWRMLGYVTPVKNQGYCASSWAFSATGSLEGQMFKKTGRLVPLSEQNLLDCMGSNVTHDCSGGFMQNAFQYVKDNGGLATEESYPYIG-----PGRKCRYHAENSAANVRDFVQIPGREEALMK-AVAKVGPISVAVDASHDSFQFYDSGIYYEPQCKRVHLNHAVLVVGYGFEGEESDGNSYWLVKNSWGEEWGMKGYIKIAKDWNNHCGIATLATYPIV 333          
BLAST of Cathepsin L vs. Ensembl Mouse
Match: Ctss (cathepsin S [Source:MGI Symbol;Acc:MGI:107341])

HSP 1 Score: 204.912 bits (520), Expect = 8.663e-63
Identity = 127/318 (39.94%), Postives = 180/318 (56.60%), Query Frame = 2
Query:  143 DGEFQTFKQRYNKSYSSMHEENSRFLNFISSLLEINHHNQLYENGQKSYEIGINHLSDWSGEE----LAQLTKLKQSNLTGSSYLSSNVKIDLPDSFDWREKGAVTEVKNQGFCGSCYAFATTGTLEAQIWRKTGKLISLSEQQIVXXXXXXXXXXX----XFVQDALSYIKSNGGIENEESYPYISSETFKPNSKCNFFKSKVVATDTGFVQMPANDETKMKEALVTIGPISVAISAT-KSLKRYTSGIFHEDECDKLKLNHAVLIVGYGTDQTSGTPYWIIKNSWSSFWGENGYFRLPR-NINACKVAMMPVYPLV 1066
            D  +  +K+ + K Y   +EE  R L +  +L  I  HN  Y  G  +Y++G+N + D + EE    +  L   +QS  T +    SN    LPD+ DWREKG VTEVK QG CG+C+AF+  G LE Q+  KTGKLISLS Q +VDC   +   +     G++ +A  YI  NGGIE + SYPY +++      KC++      AT + ++Q+P  DE  +KEA+ T GP+SV I A+  S   Y SG++ +  C    +NH VL+VGYGT    G  YW++KNSW   +G+ GY R+ R N N C +A    YP +
Sbjct:   34 DYHWDLWKKTHEKEYKDKNEEEVRRLIWEKNLKFIMIHNLEYSMGMHTYQVGMNDMGDMTNEEILCRMGALRIPRQSPKTVTFRSYSNRT--LPDTVDWREKGCVTEVKYQGSCGACWAFSAVGALEGQLKLKTGKLISLSAQNLVDCSNEEKYGNKGCGGGYMTEAFQYIIDNGGIEADASYPYKATD-----EKCHYNSKNRAATCSRYIQLPFGDEDALKEAVATKGPVSVGIDASHSSFFFYKSGVYDDPSCTG-NVNHGVLVVGYGT--LDGKDYWLVKNSWGLNFGDQGYIRMARNNKNHCGIASYCSYPEI 341          
BLAST of Cathepsin L vs. UniProt/SwissProt
Match: sp|Q26636|CATL_SARPE (Cathepsin L OS=Sarcophaga peregrina OX=7386 PE=1 SV=1)

HSP 1 Score: 259.996 bits (663), Expect = 2.215e-83
Identity = 145/330 (43.94%), Postives = 208/330 (63.03%), Query Frame = 2
Query:  122 VSLLSRYDGEFQTFKQRYNKSYSSMHEENSRFLNFISSLLEINHHNQLYENGQKSYEIGINHLSDWSGEE-----------LAQLTKLKQSNLTGSSYLSSNVKIDLPDSFDWREKGAVTEVKNQGFCGSCYAFATTGTLEAQIWRKTGKLISLSEQQIVXXXXXXXXX--XXXFVQDALSYIKSNGGIENEESYPYISSETFKPNSKCNFFKSKVVATDTGFVQMPANDETKMKEALVTIGPISVAISAT-KSLKRYTSGIFHEDECDKLKLNHAVLIVGYGTDQTSGTPYWIIKNSWSSFWGENGYFRLPRNI-NACKVAMMPVYPLV 1066
            +S L     E+ T+K ++ K+Y++  EE  R   F  +  +I  HNQL+  G+ SY++G+N  +D    E           L QL + +++ L G++Y+     + +P S DWRE GAVT VK+QG CGSC+AF++TG LE Q +RK G L+SLSEQ +VDC T       +GG + +A  YIK NGGI+ E+SYPY   +       C+F K+ + ATDTGFV +P  DE KMK+A+ T+GP+SVAI A+ +S + Y+ G+++E ECD+  L+H VL+VGYGTD+ SG  YW++KNSW + WGE GY ++ RN  N C +A    YP V
Sbjct:   18 ISPLDLIKEEWHTYKLQHRKNYANEVEERFRMKIFNENRHKIAKHNQLFAQGKVSYKLGLNKYADMLHHEFKETMNGYNHTLRQLMR-ERTGLVGATYIPP-AHVTVPKSVDWREHGAVTGVKDQGHCGSCWAFSSTGALEGQHFRKAGVLVSLSEQNLVDCSTKYGNNGCNGGLMDNAFRYIKDNGGIDTEKSYPYEGID-----DSCHFNKATIGATDTGFVDIPEGDEEKMKKAVATMGPVSVAIDASHESFQLYSEGVYNEPECDEQNLDHGVLVVGYGTDE-SGMDYWLVKNSWGTTWGEQGYIKMARNQNNQCGIATASSYPTV 339          
BLAST of Cathepsin L vs. UniProt/SwissProt
Match: sp|Q95029|CATL_DROME (Cathepsin L OS=Drosophila melanogaster OX=7227 GN=Cp1 PE=2 SV=2)

HSP 1 Score: 246.514 bits (628), Expect = 1.255e-77
Identity = 136/321 (42.37%), Postives = 194/321 (60.44%), Query Frame = 2
Query:  149 EFQTFKQRYNKSYSSMHEENSRFLNFISSLLEINHHNQLYENGQKSYEIGINHLSDWSGEELAQLT-----------KLKQSNLTGSSYLSSNVKIDLPDSFDWREKGAVTEVKNQGFCGSCYAFATTGTLEAQIWRKTGKLISLSEQQIVXXXXXXXXX--XXXFVQDALSYIKSNGGIENEESYPYISSETFKPNSKCNFFKSKVVATDTGFVQMPANDETKMKEALVTIGPISVAISAT-KSLKRYTSGIFHEDECDKLKLNHAVLIVGYGTDQTSGTPYWIIKNSWSSFWGENGYFRLPRNI-NACKVAMMPVYPLV 1066
            E+ TFK  + K+Y    EE  R   F  +  +I  HNQ +  G+ S+++ +N  +D    E  QL            +    +  G +++S    + LP S DWR KGAVT VK+QG CGSC+AF++TG LE Q +RK+G L+SLSEQ +VDC T       +GG + +A  YIK NGGI+ E+SYPY + +       C+F K  V ATD GF  +P  DE KM EA+ T+GP+SVAI A+ +S + Y+ G+++E +CD   L+H VL+VG+GTD+ SG  YW++KNSW + WG+ G+ ++ RN  N C +A    YPLV
Sbjct:   58 EWHTFKLEHRKNYQDETEERFRLKIFNENKHKIAKHNQRFAEGKVSFKLAVNKYADLLHHEFRQLMNGFNYTLHKQLRAADESFKGVTFISP-AHVTLPKSVDWRTKGAVTAVKDQGHCGSCWAFSSTGALEGQHFRKSGVLVSLSEQNLVDCSTKYGNNGCNGGLMDNAFRYIKDNGGIDTEKSYPYEAID-----DSCHFNKGTVGATDRGFTDIPQGDEKKMAEAVATVGPVSVAIDASHESFQFYSEGVYNEPQCDAQNLDHGVLVVGFGTDE-SGEDYWLVKNSWGTTWGDKGFIKMLRNKENQCGIASASSYPLV 371          
BLAST of Cathepsin L vs. UniProt/SwissProt
Match: sp|O45734|CPL1_CAEEL (Cathepsin L-like OS=Caenorhabditis elegans OX=6239 GN=cpl-1 PE=1 SV=1)

HSP 1 Score: 242.276 bits (617), Expect = 1.893e-76
Identity = 131/314 (41.72%), Postives = 192/314 (61.15%), Query Frame = 2
Query:  149 EFQTFKQRYNKSYSSMHEENSRFLNFISSLLEINHHNQLYENGQKSYEIGINHLSDWSGEELAQLTKLKQ----SNLTGSSYLSSNVKIDLPDSFDWREKGAVTEVKNQGFCGSCYAFATTGTLEAQIWRKTGKLISLSEQQIVXXXXXXXXX--XXXFVQDALSYIKSNGGIENEESYPYISSETFKPNSKCNFFKSKVVATDTGFVQMPANDETKMKEALVTIGPISVAISAT-KSLKRYTSGIFHEDECDKLKLNHAVLIVGYGTDQTSGTPYWIIKNSWSSFWGENGYFRLPRNI-NACKVAMMPVYPLV 1066
            ++  +K+ ++K YS   EE +    F+ +++ I +HN+ +  G+K++E+G+NH++D    +  +L   ++    S +  SS   +   + +PD  DWR+   VT+VKNQG CGSC+AF+ TG LE Q  RK G+L+SLSEQ +VDC T       +GG +  A  YI+ N G++ EESYPY   +      KC+F K  V A D G+V  P  DE ++K A+ T GPIS+AI A  +S + Y  G+++++EC   +L+H VL+VGYGTD   G  YWI+KNSW + WGE GY R+ RN  N C VA    YPLV
Sbjct:   31 KWDDYKEDFDKEYSES-EEQTYMEAFVKNMIHIENHNRDHRLGRKTFEMGLNHIADLPFSQYRKLNGYRRLFGDSRIKNSSSFLAPFNVQVPDEVDWRDTHLVTDVKNQGMCGSCWAFSATGALEGQHARKLGQLVSLSEQNLVDCSTKYGNHGCNGGLMDQAFEYIRDNHGVDTEESYPYKGRDM-----KCHFNKKTVGADDKGYVDTPEGDEEQLKIAVATQGPISIAIDAGHRSFQLYKKGVYYDEECSSEELDHGVLLVGYGTDPEHGD-YWIVKNSWGAGWGEKGYIRIARNRNNHCGVATKASYPLV 337          
BLAST of Cathepsin L vs. UniProt/SwissProt
Match: sp|P13277|CYSP1_HOMAM (Digestive cysteine proteinase 1 OS=Homarus americanus OX=6706 GN=LCP1 PE=1 SV=2)

HSP 1 Score: 224.172 bits (570), Expect = 1.261e-69
Identity = 124/310 (40.00%), Postives = 188/310 (60.65%), Query Frame = 2
Query:  152 FQTFKQRYNKSYSSMHEENSRFLNFISSLLEINHHNQLYENGQKSYEIGINHLSDWSGEELAQLTKLKQSNLTGSSYLSSNVKIDLPDSFDWREKGAVTEVKNQGFCGSCYAFATTGTLEAQIWRKTGKLISLSEQQIVXXXXXX---XXXXXXFVQDALSYIKSNGGIENEESYPYISSETFKPNSKCNFFKSKVVATDTGFVQMPANDETKMKEALVTIGPISVAISAT-KSLKRYTSGIFHEDECDKLKLNHAVLIVGYGTDQTSGTPYWIIKNSWSSFWGENGYFRLPRNI-NACKVAMMPVYPLV 1066
            ++ FK ++ + Y  + EE  R   F+ +L  I   N+ YE G+ +Y + IN  SD + E+   + K  +     ++  +S          DWR KGAVT VK+QG CGSC+AF+TTG +E Q + KTG+L+SLSEQQ+VDC        GC+GG+V+ A+ Y++ NGG++ E SYPY + +     + C F  + + AT TG+V +    E+ +K A   IGPISVAI A+ +S + Y +G+++E  C   +L+HAVL VGYG++   G  +W++KNSW++ WGE+GY ++ RN  N C +A    YP V
Sbjct:   20 WEEFKGKFGRKYVDLEEERYRLNVFLDNLQYIEEFNKKYERGEVTYNLAINQFSDMTNEKFNAVMKGYKKGPRPAAVFTSTDAAPESTEVDWRTKGAVTPVKDQGQCGSCWAFSTTGGIEGQHFLKTGRLVSLSEQQLVDCAGGSYYNQGCNGGWVERAIMYVRDNGGVDTESSYPYEARD-----NTCRFNSNTIGATCTGYVGIAQGSESALKTATRDIGPISVAIDASHRSFQSYYTGVYYEPSCSSSQLDHAVLAVGYGSE--GGQDFWLVKNSWATSWGESGYIKMARNRNNNCGIATDACYPTV 322          
BLAST of Cathepsin L vs. UniProt/SwissProt
Match: sp|P55097|CATK_MOUSE (Cathepsin K OS=Mus musculus OX=10090 GN=Ctsk PE=1 SV=2)

HSP 1 Score: 223.787 bits (569), Expect = 2.516e-69
Identity = 130/330 (39.39%), Postives = 202/330 (61.21%), Query Frame = 2
Query:  101 KFELENMVSLL----SRYDGEFQTFKQRYNKSYSSMHEENSRFLNFISSLLEINHHNQLYENGQKSYEIGINHLSDWSGEELAQ-LTKLK---QSNLTGSSYLSSNVKIDLPDSFDWREKGAVTEVKNQGFCGSCYAFATTGTLEAQIWRKTGKLISLSEQQIVXXXXXXXXXXXXFVQDALSYIKSNGGIENEESYPYISSETFKPNSKCNFFKSKVVATDTGFVQMPANDETKMKEALVTIGPISVAISAT-KSLKRYTSGIFHEDECDKLKLNHAVLIVGYGTDQTSGTPYWIIKNSWSSFWGENGYFRLPRNI-NACKVAMMPVYP 1060
            KF L  MVS         D +++ +K+ + K Y+S  +E SR L +  +L +I+ HN     G  +YE+ +NHL D + EE+ Q +T L+     + +  +  +   +  +PDS D+R+KG VT VKNQG CGSC+AF++ G LE Q+ +KTGKL++LS Q +VDC T + GC GG++  A  Y++ NGGI++E++YPY+  +       C +  +   A   G+ ++P  +E  +K A+  +GPISV+I A+  S + Y+ G+++++ CD+  +NHAVL+VGYGT +  G+ +WIIKNSW   WG  GY  L RN  NAC +  M  +P
Sbjct:    5 KFLLLPMVSFALSPEEMLDTQWELWKKTHQKQYNSKVDEISRRLIWEKNLKQISAHNLEASLGVHTYELAMNHLGDMTSEEVVQKMTGLRIPPSRSYSNDTLYTPEWEGRVPDSIDYRKKGYVTPVKNQGQCGSCWAFSSAGALEGQLKKKTGKLLALSPQNLVDCVTENYGCGGGYMTTAFQYVQQNGGIDSEDAYPYVGQD-----ESCMYNATAKAAKCRGYREIPVGNEKALKRAVARVGPISVSIDASLASFQFYSRGVYYDENCDRDNVNHAVLVVGYGTQK--GSKHWIIKNSWGESWGNKGYALLARNKNNACGITNMASFP 327          
BLAST of Cathepsin L vs. TrEMBL
Match: A0A267GB11 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig008319g1 PE=3 SV=1)

HSP 1 Score: 274.633 bits (701), Expect = 2.728e-86
Identity = 161/374 (43.05%), Postives = 233/374 (62.30%), Query Frame = 2
Query:   11 ILICLLLAVISEARTTYSHHKSVPSDDISSKFELENMVS--LLSRYDG-----------EFQTFKQRYNKSYSSMHEENSRFLNFISSLLEINHHNQLYENGQKSYEIGINHLSDWSGEE-LAQLTKLKQSNLTGS---SYLSSNVKIDLPDSFDWREKGAVTEVKNQGFCGSCYAFATTGTLEAQIWRKTGKLISLSEQQIVXXXXXX---XXXXXXFVQDALSYIKSNGGIENEESYPYISSETFKPNSKCNFFKSKVVATDTGFVQMPANDETKMKEALVTIGPISVAISATK-SLKRYTSGIFHEDECDKLKLNHAVLIVGYGTDQTSGTPYWIIKNSWSSFWGENGYFRLPRNI-NACKVAMMPVYPLV 1066
            + + L++A++S A T  ++    P  DI    EL +  S  L+ R DG           ++  FK+R+ ++Y  +  E  R   F+ +LL I  HN L ++GQK+Y +G+   +D +  E LA++T LK+++  G    SY+S  V+  LPD+ DWR+KGAVT VKNQG CGSC++F+TTG+LE Q +RKTG+L+SLSEQQ+VDC        GC+GG + +A  YI+ + GIE E  YPY ++E     S+C + +S+V A  TGFV +P   E K+KEA+  +GP+SVAI A+  S + Y SG+++E  C   +L+H VL+VGYGT   SG+ YW++KNSWS  WGE GY R+ RN  N C +A    YP V
Sbjct:    1 MRVALIVALLSMALTANTN----PMPDIVRMTELNSDESSYLIGRPDGHERLRIEQFHKDWSRFKERFGRTYEDLTFERQRMEVFVRNLLYIRQHNALAKSGQKTYTLGVGPFADMTHSEFLARMTGLKRTDTFGRGRISYISPAVEQALPDTVDWRKKGAVTPVKNQGQCGSCWSFSTTGSLEGQHFRKTGRLLSLSEQQLVDCAGGRYGNQGCNGGLMDNAFMYIRDH-GIELESDYPYQAAE-----SRCQYQRSRVAANCTGFVDIPQGSEDKLKEAVANVGPVSVAIDASHPSFQHYQSGVYNEPACSSQQLDHGVLVVGYGT--LSGSDYWLVKNSWSDMWGEKGYIRMSRNKNNQCGIASTASYPTV 362          
BLAST of Cathepsin L vs. TrEMBL
Match: A0A267DZX3 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig002369g2 PE=3 SV=1)

HSP 1 Score: 274.633 bits (701), Expect = 2.879e-86
Identity = 161/374 (43.05%), Postives = 233/374 (62.30%), Query Frame = 2
Query:   11 ILICLLLAVISEARTTYSHHKSVPSDDISSKFELENMVS--LLSRYDG-----------EFQTFKQRYNKSYSSMHEENSRFLNFISSLLEINHHNQLYENGQKSYEIGINHLSDWSGEE-LAQLTKLKQSNLTGS---SYLSSNVKIDLPDSFDWREKGAVTEVKNQGFCGSCYAFATTGTLEAQIWRKTGKLISLSEQQIVXXXXXX---XXXXXXFVQDALSYIKSNGGIENEESYPYISSETFKPNSKCNFFKSKVVATDTGFVQMPANDETKMKEALVTIGPISVAISATK-SLKRYTSGIFHEDECDKLKLNHAVLIVGYGTDQTSGTPYWIIKNSWSSFWGENGYFRLPRNI-NACKVAMMPVYPLV 1066
            + + L++A++S A T  ++    P  DI    EL +  S  L+ R DG           ++  FK+R+ ++Y  +  E  R   F+ +LL I  HN L ++GQK+Y +G+   +D +  E LA++T LK+++  G    SY+S  V+  LPD+ DWR+KGAVT VKNQG CGSC++F+TTG+LE Q +RKTG+L+SLSEQQ+VDC        GC+GG + +A  YI+ + GIE E  YPY ++E     S+C + +S+V A  TGFV +P   E K+KEA+  +GP+SVAI A+  S + Y SG+++E  C   +L+H VL+VGYGT   SG+ YW++KNSWS  WGE GY R+ RN  N C +A    YP V
Sbjct:    1 MRVALIVALLSMALTANTN----PMPDIVRMTELNSDESSYLIGRPDGHERLRIEQFHKDWSRFKERFGRTYEDLTFERQRMEVFVRNLLYIRQHNALAKSGQKTYTLGVGPFADMTHSEFLARMTGLKRTDTFGRGRISYISPAVEQALPDTVDWRKKGAVTPVKNQGQCGSCWSFSTTGSLEGQHFRKTGRLLSLSEQQLVDCAGGRYGNQGCNGGLMNNAFMYIRDH-GIELESDYPYQAAE-----SRCQYQRSRVAANCTGFVDIPQGSEDKLKEAVANVGPVSVAIDASHPSFQHYQSGVYNEPACSSQQLDHGVLVVGYGT--LSGSDYWLVKNSWSDMWGEKGYIRMSRNKNNQCGIASTASYPTV 362          
BLAST of Cathepsin L vs. TrEMBL
Match: A0A1I8J130 (Uncharacterized protein OS=Macrostomum lignano OX=282301 PE=3 SV=1)

HSP 1 Score: 270.396 bits (690), Expect = 7.470e-85
Identity = 156/351 (44.44%), Postives = 221/351 (62.96%), Query Frame = 2
Query:   80 PSDDISSKFELENMVS--LLSRYDG-----------EFQTFKQRYNKSYSSMHEENSRFLNFISSLLEINHHNQLYENGQKSYEIGINHLSDWSGEE-LAQLTKLKQSNLTGS---SYLSSNVKIDLPDSFDWREKGAVTEVKNQGFCGSCYAFATTGTLEAQIWRKTGKLISLSEQQIVXXXXXX---XXXXXXFVQDALSYIKSNGGIENEESYPYISSETFKPNSKCNFFKSKVVATDTGFVQMPANDETKMKEALVTIGPISVAISATK-SLKRYTSGIFHEDECDKLKLNHAVLIVGYGTDQTSGTPYWIIKNSWSSFWGENGYFRLPRNI-NACKVAMMPVYPLV 1066
            P  DI    EL +  S  L+ R DG           ++  FK+R+ ++Y  +  E  R   F+ +LL I  HN L ++GQK+Y +G+   +D +  E LA++T LK+++  G    SY+S  V+  LPD+ DWR+KGAVT VKNQG CGSC++F+TTG+LE Q +RKTG+L+SLSEQQ+VDC        GC+GG + +A  YI+ + GIE E  YPY ++E     S+C + +S+V A  TGFV +P   E K+KEA+  +GP+SVAI A+  S + Y SG+++E  C+  +L+H VL+VGYGT   SG+ YW++KNSWS  WGE GY R+ RN  N C +A    YP V
Sbjct:    9 PMPDIVRMTELNSDESSYLIGRPDGHERLRIEQFHKDWSRFKERFGRTYEDLTFERQRMEVFVRNLLYIRQHNALAKSGQKTYTLGVGPFADMTHSEFLARMTGLKRTDTFGRGRISYISPAVEQALPDTVDWRKKGAVTPVKNQGQCGSCWSFSTTGSLEGQHFRKTGRLLSLSEQQLVDCAGGRYGNQGCNGGLMDNAFMYIRDH-GIELESDYPYQAAE-----SRCQYQRSRVAANCTGFVDIPHGSEDKLKEAVANVGPVSVAIDASHPSFQHYQSGVYNEPACNSQQLDHGVLVVGYGT--LSGSDYWLVKNSWSDMWGEKGYIRMSRNKNNQCGIASTASYPTV 351          
BLAST of Cathepsin L vs. TrEMBL
Match: A0A1I8IYR5 (Uncharacterized protein OS=Macrostomum lignano OX=282301 PE=3 SV=1)

HSP 1 Score: 270.396 bits (690), Expect = 1.001e-84
Identity = 156/351 (44.44%), Postives = 220/351 (62.68%), Query Frame = 2
Query:   80 PSDDISSKFELENMVS--LLSRYDG-----------EFQTFKQRYNKSYSSMHEENSRFLNFISSLLEINHHNQLYENGQKSYEIGINHLSDWSGEE-LAQLTKLKQSNLTGS---SYLSSNVKIDLPDSFDWREKGAVTEVKNQGFCGSCYAFATTGTLEAQIWRKTGKLISLSEQQIVXXXXXX---XXXXXXFVQDALSYIKSNGGIENEESYPYISSETFKPNSKCNFFKSKVVATDTGFVQMPANDETKMKEALVTIGPISVAISATK-SLKRYTSGIFHEDECDKLKLNHAVLIVGYGTDQTSGTPYWIIKNSWSSFWGENGYFRLPRNI-NACKVAMMPVYPLV 1066
            P  DI    EL +  S  L+ R DG           ++  FK+R+ ++Y  +  E  R   F+ +LL I  HN L ++GQK+Y +G+   +D +  E LA++T LK+++  G    SY+S  V+  LPD+ DWR+KGAVT VKNQG CGSC++F+TTG+LE Q +RKTG+L+SLSEQQ+VDC        GC+GG + +A  YI+ + GIE E  YPY ++E     S+C + +S+V A  TGFV +P   E K+KEA+  +GP+SVAI A+  S + Y SG+++E  C   +L+H VL+VGYGT   SG+ YW++KNSWS  WGE GY R+ RN  N C +A    YP V
Sbjct:    9 PMPDIVRMTELNSDESSYLIGRPDGHERLRIEQFHKDWSRFKERFGRTYEDLTFERQRMEVFVRNLLYIRQHNALAKSGQKTYTLGVGPFADMTHSEFLARMTGLKRTDTFGRGRISYISPAVEQALPDTVDWRKKGAVTPVKNQGQCGSCWSFSTTGSLEGQHFRKTGRLLSLSEQQLVDCAGGRYGNQGCNGGLMNNAFMYIRDH-GIELESDYPYQAAE-----SRCQYQRSRVAANCTGFVDIPQGSEDKLKEAVANVGPVSVAIDASHPSFQHYQSGVYNEPACSSQQLDHGVLVVGYGT--LSGSDYWLVKNSWSDMWGEKGYIRMSRNKNNQCGIASTASYPTV 351          
BLAST of Cathepsin L vs. TrEMBL
Match: K1R5E7 (Cathepsin L OS=Crassostrea gigas OX=29159 GN=CGI_10010587 PE=3 SV=1)

HSP 1 Score: 268.47 bits (685), Expect = 6.076e-84
Identity = 149/317 (47.00%), Postives = 212/317 (66.88%), Query Frame = 2
Query:  140 YDGEFQTFKQRYNKSYSSMHEENSRFLNFISSLLEINHHNQLYENGQKSYEIGINHLSDWSGEELAQLTKLKQSNLTG---SSYLSSNVKIDLPDSFDWREKGAVTEVKNQGFCGSCYAFATTGTLEAQIWRKTGKLISLSEQQIVXXXXX--XXXXXXXFVQDALSYIKSNGGIENEESYPYISSETFKP-NSKCNFFKSKVVATDTGFVQMPANDETKMKEALVTIGPISVAISAT-KSLKRYTSGIFHEDECDKLKLNHAVLIVGYGTDQTSGTPYWIIKNSWSSFWGENGYFRLPRN-INACKVAMMPVYPLV 1066
            Y+  ++ FK  ++K+Y ++ EE+ RF  F  ++ +I  HN+LY  G+KSY +G+N  SD   EE  +   LK+++L     SSYL++N  ++ PDS DWR+KG VT+VKNQG CGSC++F+TTG+LE Q +RK+GKL+SLSE Q+VDC  +  ++GC+GG + +A  YIKS GG+E+EE YPY      KP    C F  +KV ATDTG V + +  E+ +K+A+  +GP+SVAI A+  S + Y  G++ E EC   +L+H VL VGYGTD   G  YWI+KNSW + WGE+GY ++ RN  N C +A    YPLV
Sbjct:   52 YEQAWKEFKILHDKTYDALEEESRRFEIFRENVQKIEEHNKLYHLGKKSYYLGVNQFSDLKHEEFVKYNGLKKTSLKDGGCSSYLAANNLVE-PDSVDWRKKGYVTDVKNQGQCGSCWSFSTTGSLEGQHFRKSGKLVSLSESQLVDCSQSFGNEGCNGGLMDNAFKYIKSVGGLESEEDYPY------KPKQGTCKFDDTKVAATDTGCVDVESGSESALKKAVSEVGPVSVAIDASHSSFQSYAGGVYDEPECSSEQLDHGVLCVGYGTDD-QGQDYWIVKNSWGAEWGEDGYVKMSRNKKNQCGIATQASYPLV 360          
BLAST of Cathepsin L vs. Ensembl Cavefish
Match: ENSAMXT00000040914.1 (pep primary_assembly:Astyanax_mexicanus-2.0:APWO02000030.1:116984:135874:-1 gene:ENSAMXG00000037672.1 transcript:ENSAMXT00000040914.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 254.988 bits (650), Expect = 1.923e-82
Identity = 142/315 (45.08%), Postives = 196/315 (62.22%), Query Frame = 2
Query:  143 DGEFQTFKQRYNKSYSSMHEENSRFLNFISSLLEINHHNQLYENGQKSYEIGINHLSDWSGEELAQLTKL-----KQSNLTGSSYLSSNVKIDLPDSFDWREKGAVTEVKNQGFCGSCYAFATTGTLEAQIWRKTGKLISLSEQQIVXXXXXXXXXXXXFVQDALSYIKSNGGIENEESYPYISSETFKPNSKCNFFKSKVVATDTGFVQMPANDETKMKEALVTIGPISVAISATK-SLKRYTSGIFHEDECDKLKLNHAVLIVGYGTDQTSGTPYWIIKNSWSSFWGENGYFRLPRN-INACKVAMMPVYPLV 1066
            D EFQ +K ++ K Y  M EE+ R +N++++   +  HN L + G K+Y +G+NH +D   +E  Q+ K      K  N T     +      LPD+ DWR +G VT VK QG CGSC+AF+ TG LE Q++RKTG+L+SLSEQQ+VDC T + GCDGG++  A  Y+  N G++ E SYPY   +      KC F    V AT TG+    + DE  ++EA+ TIGPISV I A + S ++YTSG+++E  C   K  HAVL+VGYGT+  +G  YW++KNSW + WGENGY ++ RN  N C +A  P YPLV
Sbjct:   21 DLEFQEWKLKFGKKYHLMEEESQRKMNWMTNRKLVLEHNMLADQGLKTYRLGMNHFADMDNQEYRQMLKGFFNRNKAHNATTLLQKTEGSAAALPDTVDWRTRGYVTGVKTQGICGSCWAFSVTGALEGQMFRKTGRLVSLSEQQLVDCTTRNFGCDGGYLDRAFDYVMKNRGLDTEASYPYEDRQW-----KCRFNPKTVGATCTGYRSTRSGDEKALQEAVATIGPISVVIDAGQVSFQQYTSGVYNEPHCSSGKY-HAVLVVGYGTE--NGQDYWLVKNSWGTLWGENGYIKMSRNKYNQCGIATEPYYPLV 327          
BLAST of Cathepsin L vs. Ensembl Cavefish
Match: ENSAMXT00000001970.2 (cathepsin L1-like [Source:NCBI gene;Acc:103022163])

HSP 1 Score: 247.284 bits (630), Expect = 1.865e-79
Identity = 141/318 (44.34%), Postives = 200/318 (62.89%), Query Frame = 2
Query:  143 DGEFQTFKQRYNKSYSSMHEENSRFLNFISSLLEINHHNQLYENGQKSYEIGINHLSDWSGEEL-AQLTKLKQS-----NLTGSSYLSSNVKIDLPDSFDWREKGAVTEVKNQGFCGSCYAFATTGTLEAQIWRKTGKLISLSEQQIVXXXXX--XXXXXXXFVQDALSYIKSNGGIENEESYPYISSETFKPNSKCNFFKSKVVATDTGFVQMPANDETKMKEALVTIGPISVAISATK-SLKRYTSGIFHEDECDKLKLNHAVLIVGYGTDQTSGTPYWIIKNSWSSFWGENGYFRLPRN-INACKVAMMPVYPLV 1066
            D EF ++K ++ KSY S  EE+ R + ++++   +  HN L + G KSY +G+N  +D   +E  A  +   +S     +L  S++LS +    LP   DWR KG VT VKNQG CGSC+AF+ TG LE Q++RKTGKLISLSEQQ+VDC  +  + GC+GG+   +  YIKS+ G+E + +YPY + +       C F   +V+AT +GF  +P  DE  +K A+ +IGPISV I  +K + + Y SG++ E  C   KLNHAVL+VGY  D T G PYW++KNSW   WG+NGY ++ RN +N C +A +  YPLV
Sbjct:   23 DLEFNSWKLQHGKSYGSEEEESQRKMIWLTNRKLVLKHNMLADQGLKSYRLGMNIFADMKNQEFQAMFSHCVKSFDETDSLCTSTFLSEDEDAPLPQRVDWRAKGYVTFVKNQGICGSCWAFSATGALEGQMFRKTGKLISLSEQQLVDCSQSFGNLGCNGGWPSKSFDYIKSSKGLEADFTYPYKARKEI-----CRFNPQRVIATCSGFKSLPKGDENALKNAVASIGPISVLIDTSKHTFQLYKSGVYDEPGCSSTKLNHAVLLVGYDNDPT-GKPYWLVKNSWGINWGDNGYIKMSRNKMNQCGIATIATYPLV 334          
BLAST of Cathepsin L vs. Ensembl Cavefish
Match: ctsl.1 (cathepsin L1-like [Source:NCBI gene;Acc:103023607])

HSP 1 Score: 243.817 bits (621), Expect = 5.099e-78
Identity = 141/318 (44.34%), Postives = 197/318 (61.95%), Query Frame = 2
Query:  143 DGEFQTFKQRYNKSYSSMHEENSRFLNFISSLLEINHHNQLYENGQKSYEIGINHLSDWSGEELAQL--TKLKQSNLT----GSSYLSSNVKIDLPDSFDWREKGAVTEVKNQGFCGSCYAFATTGTLEAQIWRKTGKLISLSEQQIVXXXXXXX--XXXXXFVQDALSYIKSNGGIENEESYPYISSETFKPNSKCNFFKSKVVATDTGFVQMPANDETKMKEALVTIGPISVAISAT-KSLKRYTSGIFHEDECDKLKLNHAVLIVGYGTDQTSGTPYWIIKNSWSSFWGENGYFRLPRN-INACKVAMMPVYPLV 1066
            D EF  +K ++ K Y S+ EE+ R L ++++   +  HN L + G KSY +G+   +D   +E  +L  + L   N T     +++L   ++  LPD+ DWR KG VT++K+Q  CGSC+AF+ TG+LE Q +RKTGKL+SLSEQQ+VDC  +    GC GG +  A  YIK+N GI+ E+SYPY + +       C F    V AT TGFV + + DE  ++EA+ TIGPISVAI A   S + Y SGI++E +C   +L+H VL VGYGTD  +G  YW++KNSW   WG  GY ++ RN  N C +A M  YPLV
Sbjct:   23 DLEFHAWKLKFGKIYHSVEEESQRKLTWLTNRKLVLVHNMLADQGIKSYRLGMTFFADMDNKEYRKLFASCLGSFNRTKAHSATTFLRQTLRDPLPDTVDWRPKGYVTDIKDQKDCGSCWAFSATGSLEGQTFRKTGKLVSLSEQQLVDCSGDYGNFGCGGGLMDQAFEYIKANKGIDTEDSYPYEAVD-----GDCRFKPDSVGATCTGFVDITSGDEKALQEAVATIGPISVAIDAGHSSFQLYESGIYNEPDCSSTELDHGVLAVGYGTD--NGKDYWLVKNSWGLDWGNKGYIQMSRNEDNQCGIATMSSYPLV 333          
BLAST of Cathepsin L vs. Ensembl Cavefish
Match: ENSAMXT00000047972.1 (pep primary_assembly:Astyanax_mexicanus-2.0:APWO02000030.1:138766:150097:-1 gene:ENSAMXG00000038942.1 transcript:ENSAMXT00000047972.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 241.121 bits (614), Expect = 5.525e-77
Identity = 135/319 (42.32%), Postives = 198/319 (62.07%), Query Frame = 2
Query:  143 DGEFQTFKQRYNKSYSSMHEENSRFLNFISSLLEINHHNQLYENGQKSYEIGINHLSDWSGEE--------LAQLTKLKQSNLTGSSYLSSNVKIDLPDSFDWREKGAVTEVKNQGFCGSCYAFATTGTLEAQIWRKTGKLISLSEQQIVXXXXX--XXXXXXXFVQDALSYIKSNGGIENEESYPYISSETFKPNSKCNFFKSKVVATDTGFVQMPANDETKMKEALVTIGPISVAISATKSLKRYTSGIFHEDECDKLKLNHAVLIVGYGTDQTSGTPYWIIKNSWSSFWGENGYFRLPRNI-NACKVAMMPVYPLV 1066
            D EFQ +K ++ KSYSS  EE+ R + ++++L  +  HN L + G KS+ +G+NH +D   +E        L      K  N T   +        +PD+ DWR +G VTEVK+QG CGSC+AF++TG LE Q+++KTG L+SLSEQQ+VDC  +  ++GC+GG +  A +Y+ +NGG++ E SYPY        +S C F +  V AT +G+  + +  E ++KE + T+GP+SVA+ A  S + Y SGI+ E +C   +LNH VL VGYG+   +G  YW++KNSWS+ WGE GY R+ RN  N C +A   +YP V
Sbjct:   21 DLEFQEWKLKFGKSYSSEAEESQRKMIWMTNLKLVLEHNMLADQGLKSHRLGMNHFADMENQEFRKMLSRCLGSFDTTKIHNAT--KFTGKAGGAAVPDTVDWRTQGYVTEVKSQGLCGSCWAFSSTGALEGQMFKKTGSLVSLSEQQLVDCSESYGNNGCNGGLMSYAFNYVMNNGGLDTEASYPYEG-----QDSVCRFNQYSVGATCSGYTFISSGSEEELKEVVGTVGPVSVAVDAEVSFQLYQSGIYDESDCSSTQLNHGVLAVGYGSQ--NGKDYWLVKNSWSTSWGEAGYIRMSRNKNNQCGIATFALYPEV 330          
BLAST of Cathepsin L vs. Ensembl Cavefish
Match: ENSAMXT00000034892.1 (cathepsin L1-like [Source:NCBI gene;Acc:107196839])

HSP 1 Score: 236.498 bits (602), Expect = 3.924e-75
Identity = 138/318 (43.40%), Postives = 197/318 (61.95%), Query Frame = 2
Query:  143 DGEFQTFKQRYNKSYSSMHEENSRFLNFISSLLEINHHNQLYENGQKSYEIGINHLSDWSGEEL-AQLTKLKQS-----NLTGSSYLSSNVKIDLPDSFDWREKGAVTEVKNQGFCGSCYAFATTGTLEAQIWRKTGKLISLSEQQIVXXXXX--XXXXXXXFVQDALSYIKSNGGIENEESYPYISSETFKPNSKCNFFKSKVVATDTGFVQMPANDETKMKEALVTIGPISVAISATK-SLKRYTSGIFHEDECDKLKLNHAVLIVGYGTDQTSGTPYWIIKNSWSSFWGENGYFRLPRN-INACKVAMMPVYPLV 1066
            D EF ++K ++ KSY S  EE+ R + ++++   +  HN L + G KSY +G+N   D   +E  A  +   +S     +L  S++LS      LP   DWR+KG VT+VK+Q  CGSC+AF+ TG LE Q++RKTGKLISLSE+Q+VDC  +  + GC+GG+   +  YIKSN G+E + +YPY   E       C F   +VVAT +GF  +P  DE  +K+A+  IGPISVAI  +K + + Y SG++ E  C   +LNHAV++VGYG +   G  YW++KNSW   WG+NGY ++ RN +N C +A    YPLV
Sbjct:   24 DLEFNSWKLQHGKSYDSEEEESQRKMIWLNNRKLVLEHNMLADQGLKSYRLGMNIFGDMENQEFQAMFSHCVKSFNETDSLCTSTFLSEEEDTPLPRRVDWRKKGYVTDVKDQMSCGSCWAFSATGALEGQMFRKTGKLISLSEKQLVDCSQSFGNRGCNGGWPSKSFEYIKSNQGLEADFTYPYKPRE-----ETCRFNPQRVVATCSGFECLPQGDENALKKAVAKIGPISVAIDTSKHTFQLYKSGVYDEPGCSSTRLNHAVVLVGYG-NAPRGKQYWLVKNSWGIGWGDNGYIKMSRNKMNQCGIATDATYPLV 335          
BLAST of Cathepsin L vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006499.1 (pep scaffold:Pmarinus_7.0:GL477089:42202:47941:1 gene:ENSPMAG00000005817.1 transcript:ENSPMAT00000006499.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 217.624 bits (553), Expect = 1.662e-68
Identity = 126/318 (39.62%), Postives = 184/318 (57.86%), Query Frame = 2
Query:  143 DGEFQTFKQRYNKSYSSMHEENSRFLNFISSLLEINHHNQLYENGQKSYEIGINHLSDWSGEELAQLTK----LKQSNLTGSSYLSSNVKIDLPDSFDWREKGAVTEVKNQGFCGSCYAFATTGTLEAQIWRKTGKLISLSEQQIVXXXXXXXXX--XXXFVQDALSYIKSNGGIENEESYPYISSETFKPNSKCNFFKSKVVATDTGFVQMPANDETKMKEALVTIGPISVAISAT-KSLKRYTSGIFHEDECDKLKLNHAVLIVGYGTDQT--SGTPYWIIKNSWSSFWGENGYFRLPRN-INACKVAMMPVYPLV 1066
            D E+ ++K  + K Y    E   R + +  +L +I  HN  +  G+ ++ +G+NH  D + EE  Q       ++   ++  S        + P + DWR+KG VTEVK+QG CGSC+AF+TTG LE Q  RK G+L+SLSEQ +VDC   +      GG +  A  Y+K NGGI++E +YPY  ++      KC++      A DTGFV + + DE  +K A+ ++GP+SVAI A+ +S + Y SG++ E +C    L+H VL+VGYG   T  +G  YWI+KNSWS  WG+ GY  + RN  N C +A    YPLV
Sbjct:   27 DEEWGSWKGFHQKLYEPKQESWRRMI-WEKNLNKIKIHNLEHSLGKHTWRMGMNHFGDMTNEEFRQKMNGYHGVQPHKVSKGSTFLVPQNYEAPPTVDWRDKGLVTEVKDQGECGSCWAFSTTGALEGQHMRKVGQLVSLSEQNLVDCSRAEGNQGCGGGLMDQAFQYVKDNGGIDSEAAYPYTGTD----GDKCHYDPKFNSANDTGFVDVTSGDEKALKIAVASVGPVSVAIDASHESFQFYQSGVYFEPDCSSQDLDHGVLVVGYGVKGTGENGKKYWIVKNSWSPKWGDEGYVLMARNKKNHCGIATAASYPLV 339          
BLAST of Cathepsin L vs. Ensembl Sea Lamprey
Match: ENSPMAT00000010475.1 (pep scaffold:Pmarinus_7.0:GL482653:10321:33550:-1 gene:ENSPMAG00000009483.1 transcript:ENSPMAT00000010475.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 213.386 bits (542), Expect = 1.674e-67
Identity = 125/300 (41.67%), Postives = 185/300 (61.67%), Query Frame = 2
Query:  200 EENSRFLNFISSLLEINHHNQLYENGQKSYEIGINHLSDWSGEELAQ-LTKLKQSNLT-----GSSYLSSNVKIDLPDSFDWREKGAVTEVKNQGFCGSCYAFATTGTLEAQIWRKTGKLISLSEQQIVXXXXXXXXXX--XXFVQDALSYIKSNGGIENEESYPYISS-ETFKPNSKCNFFKSKVVATDTGFVQMPANDETKMKEALVTIGPISVAISAT-KSLKRYTSGIFHEDECDKLKLNHAVLIVGYGTDQTSGTPYWIIKNSWSSFWGENGYFRLPRNI-NACKVAMMPVYPLV 1066
            EE  R + +  +L  I+ HN  +  G+ ++ +G+N  SD +GEE  Q +   +  N T     G+++++     + P+S DWR++G VT++KNQG CGSC++F+TTG+LE Q  RKTG L+SLSEQ +VDC + +      GG + +A +YIK NGGI++EESYPY    ET      C +      A  TG+V++P  DE  +  A+ ++GP+SVAI A+  S + Y SGI+ +  C    ++HAVL+VGYG D+  G  +W++KNSW   WGE GY R+ R+  N C +A M  YPLV
Sbjct:    3 EEGWRRIIWEKNLKRISVHNLEHSMGKHTWRMGMNQFSDMTGEEFQQVMLGFRGWNGTSKAPRGATFMAPAF-FEAPESVDWRKQGYVTDIKNQGDCGSCWSFSTTGSLEGQHKRKTGVLVSLSEQNLVDCSSTEGNHGCNGGLMINAFNYIKKNGGIDSEESYPYKGQVET------CKYDPKNKAAEVTGYVEIPEGDEEALMNAVASVGPVSVAIDASLASFQSYGSGIYKDAMCSH-HIDHAVLVVGYGVDEM-GQKFWLVKNSWGVTWGEQGYVRMARDDNNLCGIATMSSYPLV 293          
BLAST of Cathepsin L vs. Ensembl Sea Lamprey
Match: ENSPMAT00000003800.1 (pep scaffold:Pmarinus_7.0:GL485125:12828:20107:1 gene:ENSPMAG00000003453.1 transcript:ENSPMAT00000003800.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 213.386 bits (542), Expect = 1.778e-67
Identity = 124/300 (41.33%), Postives = 184/300 (61.33%), Query Frame = 2
Query:  197 HEENSRFLNFISSLLEINHHNQLYENGQKSYEIGINHLSDWSGEELAQ-LTKLKQSNLT-----GSSYLSSNVKIDLPDSFDWREKGAVTEVKNQGFCGSCYAFATTGTLEAQIWRKTGKLISLSEQQIV--XXXXXXXXXXXXFVQDALSYIKSNGGIENEESYPYISSETFKPNSKCNFFKSKVVATDTGFVQMPANDETKMKEALVTIGPISVAISAT-KSLKRYTSGIFHEDECDKLKLNHAVLIVGYGTDQTSGTPYWIIKNSWSSFWGENGYFRLPRNI-NACKVAMMPVYPLV 1066
            +EE  R + +  +L +I  HN  +  G+ ++ +G+N   D +GEE  Q +   +  N T     G+++++     + P+S DWR++G VT+VKNQG CGSC++F+TTG+LE Q  RKTG L+SLSEQ +V       + GC+GG + +A +YIK NGGI++EESYPY           C +      A  TG+V++P  DE  +K A+ ++GP+SVAI A+  S   Y SGI+ +  C  + +NHAVL+VGYG D+  G  +W++KNSW   WGE GY R+ R+  N C +A+   YPLV
Sbjct:    3 NEEGWRRMIWEQNLKKIAVHNLEHSMGKHTWRMGMNRFGDMTGEEFQQVMLGFRGWNGTSKAPRGATFMAPAF-FEAPESVDWRKQGYVTDVKNQGDCGSCWSFSTTGSLEGQHKRKTGVLVSLSEQNLVDCSSTEGNYGCNGGLMINAFNYIKKNGGIDSEESYPYKGQGV----ETCKYNPKNKAAEVTGYVEIPEGDEEALKNAVASVGPVSVAIDASLNSFLYYISGIYKDKLCSHI-INHAVLVVGYGVDE-KGDKFWLVKNSWGVQWGEKGYVRMARDDNNLCGIAVTASYPLV 295          
BLAST of Cathepsin L vs. Ensembl Sea Lamprey
Match: ENSPMAT00000011285.1 (pep scaffold:Pmarinus_7.0:GL499136:454:1347:-1 gene:ENSPMAG00000010258.1 transcript:ENSPMAT00000011285.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 209.534 bits (532), Expect = 7.740e-66
Identity = 119/300 (39.67%), Postives = 183/300 (61.00%), Query Frame = 2
Query:  197 HEENSRFLNFISSLLEINHHNQLYENGQKSYEIGINHLSDWSGEELAQ-LTKLKQSNLT-----GSSYLSSNVKIDLPDSFDWREKGAVTEVKNQGFCGSCYAFATTGTLEAQIWRKTGKLISLSEQQIVXXXXXXXXX--XXXFVQDALSYIKSNGGIENEESYPYISSETFKPNSKCNFFKSKVVATDTGFVQMPANDETKMKEALVTIGPISVAISAT-KSLKRYTSGIFHEDECDKLKLNHAVLIVGYGTDQTSGTPYWIIKNSWSSFWGENGYFRLPRNI-NACKVAMMPVYPLV 1066
            +EE  R + +  +L +I  HN  +  G+ ++ +G+N   D + EE    +  L+ SN T     G+++++       P+S DWR++G VT+VK+QG CGSC+AF+TTG+LE Q  RKTG L+SLSEQ +VDC + +      GG +  A +YIK NGGI++E SYPY + +       C +      A DTGFV +P+ +E  +K A+ ++GP+S+ I A+ +S + Y+SGI+ + +C    L+H VL+VGYG D      +WI+KNSW + WG++GY  + R+  N C +A    YPLV
Sbjct:    6 NEEGWRRMIWEKNLKKIAVHNLEHSMGKHTWRMGMNRFGDMTKEEFQHTMLGLRGSNDTSKASRGATFMAPAF-FKAPESVDWRKQGYVTDVKDQGDCGSCWAFSTTGSLEGQHKRKTGVLVSLSEQNLVDCSSAEGNNGCKGGLMDLAFTYIKKNGGIDSEASYPYTAKD-----ENCKYNPKNKAAEDTGFVDIPSGNEEALKNAVASVGPVSIGIDASLESFQLYSSGIYSDSDCSN-NLDHGVLVVGYGVDDDE-RKFWIVKNSWGTKWGDHGYILMARDKDNLCGIATAASYPLV 297          
BLAST of Cathepsin L vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007755.1 (pep scaffold:Pmarinus_7.0:GL476381:1843:17023:-1 gene:ENSPMAG00000007008.1 transcript:ENSPMAT00000007755.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 195.282 bits (495), Expect = 5.621e-60
Identity = 126/317 (39.75%), Postives = 182/317 (57.41%), Query Frame = 2
Query:  149 EFQTFKQRYNKSYSSMHEENSRFLNFISSLLEINHHNQLYENGQKSYEIGINHLSDWSGEE-----LAQLTKLKQSNLTGSSYLSSNVKIDLPDSFDWREKGAVTEVKNQGFCGSCYAFATTGTLEAQIWRKTGKLISLSEQQIVXXXXX--XXXXXXXFVQDALSYIKSNGGIENEESYPYISSETFKPNSKCNFFKSKVVATDTGFVQM--PANDETKMKEALVTIGPISVAISAT-KSLKRYTSGIFHEDECDKLKLNHAVLIVGYGTDQTSGTPYWIIKNSWSSFWGENGYFRLPRNI-NACKVAMMPVYPLV 1066
            ++ T+K  Y K Y S  E+  R   F  +L  +  HN L + G  S+ +GIN  SD    E     + +   L+       +        +LP+  DWR KG VT VK QG CGS +AF+ TG+LE Q +  TG L SLSEQQ+VDC  +  ++GC+GG  + AL YI  N GI++E SYPY  ++      KC  FK   VAT     Q   P+++E  +++A+ ++GPI++A++A   + K Y SG+F+E  CDK   NHA+L+VGYG+   SG  +WI+KNSW   WGE GY  + RN  N C +A + +YP++
Sbjct:   26 QWDTWKSTYGKHYGSEQEDAHRRDVFEQNLKRVLQHNLLADEGNVSFHLGINKYSDLELHEYHEKVVGRFWNLRNGTRRRGAPFPLRSMDNLPEQVDWRLKGYVTPVKEQGLCGSSWAFSATGSLEGQHFAATGNLTSLSEQQLVDCTKSYYNNGCNGGRSERALQYIIDNNGIDSELSYPYEHAD-----GKCR-FKPANVATKCSSYQFVEPSSNEEVLRQAVASVGPIAIAMNADLDTFKHYKSGLFNEPSCDK-SPNHAMLVVGYGS--LSGNDFWIVKNSWGEDWGEKGYIYMIRNKDNQCGIASIGIYPII 333          
BLAST of Cathepsin L vs. Ensembl Nematostella
Match: EDO45852 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RRL9])

HSP 1 Score: 244.202 bits (622), Expect = 1.150e-78
Identity = 145/336 (43.15%), Postives = 209/336 (62.20%), Query Frame = 2
Query:   92 ISSKFELENMVSLLSRYDGEFQTFKQRYNKSYSSMHEENSRFLNFISSLLEINHHNQLYENGQKSYEIGINHLSDWSGEELAQ------LTKLKQSNLTGSSYLS-SNVKIDLPDSFDWREKGAVTEVKNQGFCGSCYAFATTGTLEAQIWRKTGKLISLSEQQIVXXXXX--XXXXXXXFVQDALSYIKSNGGIENEESYPYISSETFKPNSKCNFFKSKVVATDTGFVQMPANDETKMKEALVTIGPISVAISATKS-LKRYTSGIFHEDECDKLKLNHAVLIVGYGTDQTSGTPYWIIKNSWSSFWGENGYFRLPRNI-NACKVAMMPVYPLV 1066
            ISS   +  M  L    D  ++ +K  + K Y + +EE  R   + ++L +I  HN+    G+ S+++ +NHL D +  E++Q      L K  +S   G+++L  +NVK+   DS DWR KG VT VKNQG CGSC+AF+TTG LE Q +RKTGKL+SLSEQ +VDC     ++GC+GG + +A  YIK NGGI+ E+SYPY++ +       C++ KS + A DTGFV +P  DE  +++AL ++GPIS+AI A++S    Y  G++ + +C   +L+H VL VGYGTD   G  YW++KNSW   WGE GY ++ RN  + C VA    YPLV
Sbjct:   12 ISSALAMPPMEPL---QDPNWKAWKSFHGKEYPNKNEETMRNFIWQNNLKKIVTHNE----GKHSFKLAMNHLGDMTSLEISQTLLGLKLKKHAESQPKGATFLPPANVKV--VDSIDWRSKGYVTPVKNQGQCGSCWAFSTTGALEGQHFRKTGKLVSLSEQNLVDCSGKYGNNGCEGGLMDNAFQYIKENGGIDTEKSYPYLAKDGV-----CHYNKSAIGAKDTGFVDIPTGDENALQQALASVGPISIAIDASQSTFHFYHQGVYDDPDCSSTRLDHGVLAVGYGTDD--GKDYWLVKNSWGPSWGEEGYIKIARNDHDKCGVASKASYPLV 331          
BLAST of Cathepsin L vs. Ensembl Nematostella
Match: EDO36727 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SHX1])

HSP 1 Score: 229.18 bits (583), Expect = 6.859e-73
Identity = 138/316 (43.67%), Postives = 192/316 (60.76%), Query Frame = 2
Query:  149 EFQTFKQRYNKSYSSMHEENSRFLNFISSLLEINHHNQLYENGQKSYEIGINHLSDWSGEELAQL-TKLKQ--SNLT---GSSYLSSNVKIDLPDSFDWREKGAVTEVKNQGFCGSCYAFATTGTLEAQIWRKTGKLISLSEQQIV--XXXXXXXXXXXXFVQDALSYIKSNGGIENEESYPYISSETFKPNSKCNFFKSKVVATDTGFVQMPANDETKMKEALVTIGPISVAISATK-SLKRYTSGIFHEDECDKLKLNHAVLIVGYGTDQTSGTPYWIIKNSWSSFWGENGYFRLPRNI-NACKVAMMPVYPLV 1066
            ++Q +K  + K Y+++ EE +R   +  +L +I  HN        S+ + +NHL D + +E     T ++   SN T   GS++L+ +  + +PD+ DWR++G VT VKNQG CGSC+AF+TTG+LE Q ++KTGKL+SLSEQ +V       ++GC GG +  A  YIK NGGI+ EESYPY +      N +C F KS + A DTGFV +   DE  +K A  T+GPISVAI A   S + Y SG+++   C    L+H VL+VGYGT Q  G+ YW++KNSW   WG  GY  + RN  N C VA    YPLV
Sbjct:   27 QWQAWKLFHTKKYTTVTEEGARKAIWRDNLKKIQKHNAE----GHSFTLAMNHLGDLTQDEFRYFYTGMRSHYSNYTKKQGSAFLAPS-HVQVPDTVDWRKEGYVTPVKNQGQCGSCWAFSTTGSLEGQNFKKTGKLVSLSEQNLVDCSTAYGNNGCQGGLMDYAFKYIKENGGIDTEESYPYEAR-----NDRCRFQKSNIGAVDTGFVDVTHGDEEALKTAAGTVGPISVAIDAGHMSFQFYHSGVYNNAGCSSTSLDHGVLVVGYGTYQ--GSDYWLVKNSWGERWGMEGYIMMSRNKNNQCGVATQASYPLV 330          
BLAST of Cathepsin L vs. Ensembl Nematostella
Match: EDO45953 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RRH6])

HSP 1 Score: 218.009 bits (554), Expect = 1.570e-68
Identity = 129/317 (40.69%), Postives = 185/317 (58.36%), Query Frame = 2
Query:  143 DGEFQTFKQRYNKSYSSMHEENSRFLNFISSLLEINHHNQLYENGQKSYEIGINHLSDWSGEELAQ--LTKLKQSNLTGSSYLS----SNVKIDLPDSFDWREKGAVTEVKNQGFCGSCYAFATTGTLEAQIWRKTGKLISLSEQQIV--XXXXXXXXXXXXFVQDALSYIKSNGGIENEESYPYISSETFKPNSKCNFFKSKVVATDTGFVQMPANDETKMKEALVTIGPISVAISATKSLKRYTSGIFHEDECDKLKLNHAVLIVGYGTDQTSGTPYWIIKNSWSSFWGENGYFRLPRNI-NACKVAMMPVYPLV 1066
            D E+  +K  + KSYS +HEE +R   +  +L +I  HN        SY++ +NHL D + +E     L      N T   + +    SNVKI  P S DW +KG VT VKNQG CGSC+AF+TTG++E Q +RKTG L+SLSEQ ++       ++GC GG + +A  YI+SNGGI+ E SYPY+  +       C+F  S V A  TG+  +P   E  ++ A+ T+GP+SVA+ A++  + Y+SG++    C   +L+H VL++GYG    +G  YW++KNSW   WG  GY  + RN  N C +A    YPLV
Sbjct:   24 DSEWVAWKSYHGKSYSDVHEERTRMAIWQQNLEKIKRHNAE----DHSYKMAMNHLGDLTEDEFRYFYLGVRAHHNSTKRGWATYMPPSNVKI--PSSVDWSQKGYVTGVKNQGQCGSCWAFSTTGSVEGQHFRKTGSLVSLSEQNLIDCSGSYGNNGCQGGLMDNAFRYIESNGGIDTESSYPYLGQQ-----GSCHFSSSHVGARVTGYQDIPQGSEQALQSAVATVGPVSVAVDASQ-WQFYSSGVYDNPYCSSTQLDHGVLVIGYGN--YNGQDYWLVKNSWGYSWGVEGYIMMSRNKNNQCGIASSASYPLV 326          
BLAST of Cathepsin L vs. Ensembl Nematostella
Match: EDO46465 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RPY5])

HSP 1 Score: 215.698 bits (548), Expect = 9.703e-68
Identity = 141/361 (39.06%), Postives = 200/361 (55.40%), Query Frame = 2
Query:    2 MGPILICLLLAVISEARTTYSHHKSVPSDDISSKFELENMVSLLSRYDGEFQTFKQRYNKSYSSMHEENSRFLNFISSLLEINHHNQLYENGQKSYEIGINHLSDWSGEELAQ--LTKLKQSNLTGSSYLSSNVKIDLPDSFDWREKGAVTEVKNQGFCGSCYAFATTGTLEAQIWRKTGKLISLSEQQIVXXXXX--XXXXXXXFVQDALSYIKSNGGIENEESYPYISSETFKPNSKCNFFKSKVVATDTGFVQMPANDETKMKEALVTIGPISVAISAT-KSLKRYTSGIFHEDECDKLKLNHAVLIVGYGTDQTSGTPYWIIKNSWSSFWGENGYFRLPRNI-NACKVAMMPVYPLV 1066
            M   L CLL+AV+                       +    S LS+ D ++  +K  + K+Y+   EE+ R   +  +L  +  HN   EN   SY++ +NH +D +  E  Q  +     SN TG S       + LP   DWR+KG VT VKNQG CGSC+AF++TG+LE Q +RKTGKL+SLSEQ +VDC     ++GC+GG +  A  YIK+N GI+ E+SYPY + +      +C+F    V AT TG+  +    E  ++ A+ T+GPISVAI A   S + Y +G++ E +C   +L+H VL VGYG +   G  YW++KNSW   WG NGY ++ RN  N C +A    YPLV
Sbjct:    1 MKAFLACLLVAVL-----------------------IAQCFSELSQ-DRQWHAWKDFHGKTYTG-EEEDLRRAIWNDNLEIVKKHNA--EN--HSYKLDMNHFADLTVTEFKQRFMGYRAASNSTGGSTFLPLSNVQLPAEVDWRDKGFVTAVKNQGQCGSCWAFSSTGSLEGQHFRKTGKLVSLSEQNLVDCSKKYGNNGCEGGLMDYAFKYIKNNDGIDTEQSYPYTARD-----GQCHFKPGSVGATVTGYTDVQRGSEGDLQSAVATVGPISVAIDAGHSSFQLYKTGVYSEPDCSSTQLDHGVLAVGYGAE--DGKDYWLVKNSWGEGWGMNGYIKMSRNKDNQCGIATQASYPLV 325          
BLAST of Cathepsin L vs. Ensembl Nematostella
Match: EDO42751 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S0K3])

HSP 1 Score: 174.866 bits (442), Expect = 1.781e-52
Identity = 106/217 (48.85%), Postives = 139/217 (64.06%), Query Frame = 2
Query:  404 DLPDSFDWREKGAVTEVKNQGFCGSCYAFATTGTLEAQIWRKTGKLISLSEQQIVXXXXXXXXXXXXFVQDALSYIKSNGGIENEESYPYISSETFKPNSKCNFFKSKVVATDTGFVQMPANDETKMKEALVTIGPISVAISATKSLKRYTSGIFHEDE--CDKLKLNHAVLIVGYGTDQTSGTPYWIIKNSWSSFWGENGYFRLPRNINACKVAMM 1048
            D+P+S DWR+KG VT VKNQG CGSC+AF+TTG +E Q   KTGKL+SLSEQ++VDCDT D GC+GG   +A   I+  GG+E+E  YPY  ++     SKC F K++V  T    V + + DE ++   L   GPIS+ I+A  +++ Y  GI H  +  C+   LNH VLIVGYG    +GTPYWIIKNSW   WGE GY+ + R    C +  M
Sbjct:   62 DIPESVDWRDKGVVTPVKNQGSCGSCWAFSTTGNIEGQYAIKTGKLVSLSEQELVDCDTIDKGCEGGLPSNAYKQIEKLGGLESESDYPYKGAD-----SKCKFNKAEVKVTINSSVVI-SKDEKEIAAWLAKNGPISIGINAN-AMQFYMGGIAHPWKIFCNPSSLNHGVLIVGYGV--KNGTPYWIIKNSWGPSWGEKGYYLIYRGGGCCGLNTM 269          
BLAST of Cathepsin L vs. Ensembl Medaka
Match: ctsl.1 (cathepsin L1 [Source:NCBI gene;Acc:101171789])

HSP 1 Score: 235.343 bits (599), Expect = 9.973e-75
Identity = 136/325 (41.85%), Postives = 199/325 (61.23%), Query Frame = 2
Query:  131 LSRYDGEFQTFKQRYNKSYSSMHEENSRFLNFISSLLEINHHNQLYENGQKSYEIGINHLSDWSGEELAQLTKLKQSNL---------TGSSYLSSNVKIDLPDSFDWREKGAVTEVKNQGFCGSCYAFATTGTLEAQIWRKTGKLISLSEQQIVXXXXX--XXXXXXXFVQDALSYIKSNGGIENEESYPYISSETFKPNSKCNFFKSKVVATDTGFVQMPANDETKMKEALVTIGPISVAISATK-SLKRYTSGIFHEDECDKLKLNHAVLIVGYGTDQTSGTPYWIIKNSWSSFWGENGYFRLPRN-INACKVAMMPVYPLV 1066
            LS  D EF  ++ ++ ++YSS  EE  R   ++++   +  HN L + G KSY +G+ + +D   EE  +L  + Q  L          GS++       DLP + DWR+KG VT+VK+Q  CGSC+AF+ TG+LE Q +RKTGKL+SLSEQQ+VDC  +  + GC GG + DA  YI++ GGI+ EESYPY +      + +C +    V AT TG+V + + DE  ++EA+ TIGPISV I A+  S + Y SG++ E +C   +L+H VL VGYG++  +G  YW++KNSW   WG+ GY ++ +N  N C +A    YPLV
Sbjct:   24 LSLEDLEFHAWRLKFGRTYSSPTEEAQRRQTWLNNRKLVLVHNILADQGIKSYRLGMTYFADMENEEYKRL--ISQGCLGSFNASLPRRGSTFFRLPENKDLPAAVDWRDKGYVTDVKDQKQCGSCWAFSATGSLEGQTFRKTGKLVSLSEQQLVDCSGDYGNMGCGGGLMDDAFRYIQATGGIDTEESYPYEAE-----DGECRYKPDAVGATCTGYVDVSSGDEDALQEAVATIGPISVGIDASHISFQLYESGLYDEPQCSSSELDHGVLAVGYGSE--NGQDYWLVKNSWGLTWGDQGYIKMSKNKSNQCGIATAASYPLV 339          
BLAST of Cathepsin L vs. Ensembl Medaka
Match: ctsl (cathepsin L [Source:NCBI gene;Acc:100049246])

HSP 1 Score: 224.942 bits (572), Expect = 1.239e-70
Identity = 128/324 (39.51%), Postives = 193/324 (59.57%), Query Frame = 2
Query:  125 SLLSRYDGEFQTFKQRYNKSYSSMHEENSRFLNFISSLLEINHHNQLYENGQKSYEIGINHLSDWSGEELAQL----TKLKQSNLTGSSYLSSNVKIDLPDSFDWREKGAVTEVKNQGFCGSCYAFATTGTLEAQIWRKTGKLISLSEQQIVXXXXXXXXX--XXXFVQDALSYIKSNGGIENEESYPYISSETFKPNSKCNFFKSKVVATDTGFVQMPANDETKMKEALVTIGPISVAISAT-KSLKRYTSGIFHEDECDKLKLNHAVLIVGYG--TDQTSGTPYWIIKNSWSSFWGENGYFRLPRNI-NACKVAMMPVYPLV 1066
            +L  + D  +Q +K  ++K+Y    EE  R L +  +L +I  HN  +  G+ SY +G+NH  D + EE  Q+     + +Q   +GS ++  N  ++ P + DWR+KG VT VK+QG CGSC+AF+TTG LE Q +RKTGKL+SLSEQ +VDC   +     +GG +  A  Y+K N G+++E+ YPY  ++    +  C +        DTGFV +P+  E  + +A+ ++GP+SVAI A  +S + Y SGI+ E EC   +L+H VL+VGYG   +   G  YWI+KNSWS  WG+ G+  + ++  N C +A    YPLV
Sbjct:   19 TLDPQLDQHWQLWKGWHSKNYHEK-EEGWRRLVWEKNLRKIELHNLEHSMGKHSYRLGMNHFGDMTHEEFRQIMNGYKRREQRKYSGSLFMEPNF-LEAPRAVDWRDKGYVTPVKDQGQCGSCWAFSTTGALEGQQFRKTGKLVSLSEQNLVDCSRPEGNEGCNGGLMDQAFQYVKDNQGLDSEDFYPYKGTD----DQPCQYNAQYSAVNDTGFVDIPSGKERALMKAVASVGPVSVAIDAGHESFQFYQSGIYFEKECSSDELDHGVLVVGYGFEGEDVDGKKYWIVKNSWSEKWGDKGFIYMAKDRHNHCGIATAASYPLV 336          
BLAST of Cathepsin L vs. Ensembl Medaka
Match: ctss2.1 (cathepsin S [Source:NCBI gene;Acc:101165175])

HSP 1 Score: 208.764 bits (530), Expect = 1.981e-64
Identity = 126/319 (39.50%), Postives = 186/319 (58.31%), Query Frame = 2
Query:  134 SRYDGEFQTFKQRYNKSYSSMHEENSRFLNFISSLLEINHHNQLYENGQKSYEIGINHLSDWSGEE-LAQLTKLKQ-SNLTGSSYL--SSNVKIDLPDSFDWREKGAVTEVKNQGFCGSCYAFATTGTLEAQIWRKTGKLISLSEQQIVXXXXX--XXXXXXXFVQDALSYIKSNGGIENEESYPYISSETFKPNSKCNFFKSKVVATDTGFVQMPANDETKMKEALVTIGPISVAISATK-SLKRYTSGIFHEDECDKLKLNHAVLIVGYGTDQTSGTPYWIIKNSWSSFWGENGYFRLPRNIN-ACKVAMMPVYPLV 1066
            SR D  ++ +K+ ++K Y S  E+  R   +  +L+ I  HN  Y  G  +Y++ +NH+ D + EE L Q   L+  +NL    +L   ++   ++PD  DWR+K  VT VK QG CGSC+AF+  G LE Q+ RKTGKL+ LS Q +VDC +   + GC+GGF+  A  Y+  N GI+++  YPY+          C++      A  + +  +P  DE  +KEA+ TIGPISVAI AT+     Y SG++ +  C +  +NH VL VGYGT   +G  YW++KNSW + +GE GY R+ RN N  C +AM   YP++
Sbjct:   29 SRLDIHWELWKKTHSKHYPSEEEDVHRRDLWERNLMLITMHNLEYSMGLHTYDLSMNHMGDLTQEEILQQFASLRPPTNLKREPHLFVGASGSNNIPDEMDWRQKNCVTSVKMQGSCGSCWAFSAVGALEGQLCRKTGKLVDLSPQNLVDCSSKYGNHGCNGGFMHQAFQYVIDNQGIDSDAGYPYVGV-----TQNCHYSSEYRAANCSQYSFLPEGDEGALKEAIATIGPISVAIDATRPRFAFYRSGVYDDSSCSQ-NVNHGVLAVGYGT--LNGQDYWLVKNSWGTTFGEQGYIRMARNKNDQCGIAMYGCYPIM 339          
BLAST of Cathepsin L vs. Ensembl Medaka
Match: ctsk (cathepsin K [Source:NCBI gene;Acc:101164922])

HSP 1 Score: 206.453 bits (524), Expect = 1.657e-63
Identity = 120/313 (38.34%), Postives = 176/313 (56.23%), Query Frame = 2
Query:  143 DGEFQTFKQRYNKSYSSMHEENSRFLNFISSLLEINHHNQLYENGQKSYEIGINHLSDWSGEELAQLTKLKQSNLTGSSYLSSNVK---IDLPDSFDWREKGAVTEVKNQGFCGSCYAFATTGTLEAQIWRKTGKLISLSEQQIVXXXXXXXXXXXXFVQDALSYIKSNGGIENEESYPYISSETFKPNSKCNFFKSKVVATDTGFVQMPANDETKMKEALVTIGPISVAISATK-SLKRYTSGIFHEDECDKLKLNHAVLIVGYGTDQTSGTPYWIIKNSWSSFWGENGYFRLPRNI-NACKVAMMPVYPLV 1066
            D  ++ +K  + K Y ++ EE  R   +  +L  I  HNQ    G  +Y +G+N   D + EE+ +     Q  L     +        I LP S D+R+KG VT VKNQG CGSC+AF++ G LE Q+ +KTG L+ LS Q +VDC T +DGC GG++ +A  Y++ NGGI++E +YPY+  +       C +  S + A   G+ ++P  DE  +  AL   GP+SV I A++ S   Y  GI+ +  C+K  +NHAVL VGYG +   G  +WI+KNSW   WG  GY  + RN  N C +A +  YP++
Sbjct:   25 DAHWEEWKMTHTKEYITVEEEGIRRAIWEKNLRMIEAHNQEAALGMHTYTLGMNQFGDMTQEEVVERMTGLQMPLNPEPRVPMETDGSLIKLPKSVDYRKKGMVTSVKNQGSCGSCWAFSSVGALEGQLAKKTGNLVDLSPQNLVDCVTENDGCGGGYMTNAFKYVQENGGIDSEAAYPYMGED-----QPCRYNVSGLAAQIKGYKEVPEGDEHALAVALFKAGPVSVGIDASQNSFLYYQKGIYFDRNCNKEDINHAVLAVGYGVN-AKGKKFWIVKNSWGETWGNKGYVLMARNRGNVCGIANLASYPVM 331          
BLAST of Cathepsin L vs. Ensembl Medaka
Match: cts12 (cathepsin L1-like [Source:NCBI gene;Acc:101170830])

HSP 1 Score: 202.216 bits (513), Expect = 5.449e-62
Identity = 124/309 (40.13%), Postives = 176/309 (56.96%), Query Frame = 2
Query:  173 YNKSYSSMHEENSRFLNFISSLLEINHHNQLYENGQKSYEIGINHLSDWSGEELAQLTK-------LKQSNLTGSSYLSSNVKIDLPDSFDWREKGAVTEVKNQGFCGSCYAFATTGTLEAQIWRKTGKLISLSEQQIVXXXX--XXXXXXXXFVQDALSYIKSNGGIENEESYPYISSETFKPNSKCNFFKSKVVATDTGFVQMPANDETKMKEALVTIGPISVAISAT-KSLKRYTSGIFHEDECDKLKLNHAVLIVGYGTDQTSGTPYWIIKNSWSSFWGENGYFRLPRN-INACKVAMMPVYPLV 1066
            Y +   ++ EEN R          IN HNQ +  G++ + +G+N   D +G+E   L         +K+     +  L  N +       D+R  G VTEVK+QG+CGSC+AF+TTG +E QI +KTG+L+SLSEQ +VDC       GC G ++  A  Y+ SN G++  +SYPY S +T      C +     VA    +  +P  DE  + +A+ TIGPI+VAI A   S   Y+SGI+ E  CD  +L+HAVL+VGYG+++  G  YWIIKNSW S WGE GY R+ RN  N C +A   +YP++
Sbjct:   29 YEERRRAIWEENHRM---------INDHNQRFLTGKRPFSMGMNKYGDLTGQEYRVLQGAVMNAQFVKRGKEVSARRLRYNARKSEAGFVDYRNMGYVTEVKDQGYCGSCWAFSTTGAIEGQIVKKTGQLLSLSEQNLVDCSRPYGTHGCSGAWMASAYDYVLSN-GLQTTDSYPYTSVDT----QPCFYDSRLAVAHIKDYRFIPQGDEQALADAVATIGPITVAIDADHASFLFYSSGIYDEPNCDPNRLSHAVLLVGYGSEE--GQDYWIIKNSWGSSWGEGGYMRIIRNGSNTCGIASYALYPIL 321          
BLAST of Cathepsin L vs. Planmine SMEST
Match: SMESG000063517.1 (SMESG000063517.1)

HSP 1 Score: 708.368 bits (1827), Expect = 0.000e+0
Identity = 355/355 (100.00%), Postives = 355/355 (100.00%), Query Frame = 2
Query:    2 MGPILICLLLAVISEARTTYSHHKSVPSDDISSKFELENMVSLLSRYDGEFQTFKQRYNKSYSSMHEENSRFLNFISSLLEINHHNQLYENGQKSYEIGINHLSDWSGEELAQLTKLKQSNLTGSSYLSSNVKIDLPDSFDWREKGAVTEVKNQGFCGSCYAFATTGTLEAQIWRKTGKLISLSEQQIVXXXXXXXXXXXXFVQDALSYIKSNGGIENEESYPYISSETFKPNSKCNFFKSKVVATDTGFVQMPANDETKMKEALVTIGPISVAISATKSLKRYTSGIFHEDECDKLKLNHAVLIVGYGTDQTSGTPYWIIKNSWSSFWGENGYFRLPRNINACKVAMMPVYPLV 1066
            MGPILICLLLAVISEARTTYSHHKSVPSDDISSKFELENMVSLLSRYDGEFQTFKQRYNKSYSSMHEENSRFLNFISSLLEINHHNQLYENGQKSYEIGINHLSDWSGEELAQLTKLKQSNLTGSSYLSSNVKIDLPDSFDWREKGAVTEVKNQGFCGSCYAFATTGTLEAQIWRKTGKLISLSEQQIVDCDTNDDGCDGGFVQDALSYIKSNGGIENEESYPYISSETFKPNSKCNFFKSKVVATDTGFVQMPANDETKMKEALVTIGPISVAISATKSLKRYTSGIFHEDECDKLKLNHAVLIVGYGTDQTSGTPYWIIKNSWSSFWGENGYFRLPRNINACKVAMMPVYPLV
Sbjct:    4 MGPILICLLLAVISEARTTYSHHKSVPSDDISSKFELENMVSLLSRYDGEFQTFKQRYNKSYSSMHEENSRFLNFISSLLEINHHNQLYENGQKSYEIGINHLSDWSGEELAQLTKLKQSNLTGSSYLSSNVKIDLPDSFDWREKGAVTEVKNQGFCGSCYAFATTGTLEAQIWRKTGKLISLSEQQIVDCDTNDDGCDGGFVQDALSYIKSNGGIENEESYPYISSETFKPNSKCNFFKSKVVATDTGFVQMPANDETKMKEALVTIGPISVAISATKSLKRYTSGIFHEDECDKLKLNHAVLIVGYGTDQTSGTPYWIIKNSWSSFWGENGYFRLPRNINACKVAMMPVYPLV 358          
BLAST of Cathepsin L vs. Planmine SMEST
Match: SMESG000063517.1 (SMESG000063517.1)

HSP 1 Score: 707.983 bits (1826), Expect = 0.000e+0
Identity = 355/355 (100.00%), Postives = 355/355 (100.00%), Query Frame = 2
Query:    2 MGPILICLLLAVISEARTTYSHHKSVPSDDISSKFELENMVSLLSRYDGEFQTFKQRYNKSYSSMHEENSRFLNFISSLLEINHHNQLYENGQKSYEIGINHLSDWSGEELAQLTKLKQSNLTGSSYLSSNVKIDLPDSFDWREKGAVTEVKNQGFCGSCYAFATTGTLEAQIWRKTGKLISLSEQQIVXXXXXXXXXXXXFVQDALSYIKSNGGIENEESYPYISSETFKPNSKCNFFKSKVVATDTGFVQMPANDETKMKEALVTIGPISVAISATKSLKRYTSGIFHEDECDKLKLNHAVLIVGYGTDQTSGTPYWIIKNSWSSFWGENGYFRLPRNINACKVAMMPVYPLV 1066
            MGPILICLLLAVISEARTTYSHHKSVPSDDISSKFELENMVSLLSRYDGEFQTFKQRYNKSYSSMHEENSRFLNFISSLLEINHHNQLYENGQKSYEIGINHLSDWSGEELAQLTKLKQSNLTGSSYLSSNVKIDLPDSFDWREKGAVTEVKNQGFCGSCYAFATTGTLEAQIWRKTGKLISLSEQQIVDCDTNDDGCDGGFVQDALSYIKSNGGIENEESYPYISSETFKPNSKCNFFKSKVVATDTGFVQMPANDETKMKEALVTIGPISVAISATKSLKRYTSGIFHEDECDKLKLNHAVLIVGYGTDQTSGTPYWIIKNSWSSFWGENGYFRLPRNINACKVAMMPVYPLV
Sbjct:    1 MGPILICLLLAVISEARTTYSHHKSVPSDDISSKFELENMVSLLSRYDGEFQTFKQRYNKSYSSMHEENSRFLNFISSLLEINHHNQLYENGQKSYEIGINHLSDWSGEELAQLTKLKQSNLTGSSYLSSNVKIDLPDSFDWREKGAVTEVKNQGFCGSCYAFATTGTLEAQIWRKTGKLISLSEQQIVDCDTNDDGCDGGFVQDALSYIKSNGGIENEESYPYISSETFKPNSKCNFFKSKVVATDTGFVQMPANDETKMKEALVTIGPISVAISATKSLKRYTSGIFHEDECDKLKLNHAVLIVGYGTDQTSGTPYWIIKNSWSSFWGENGYFRLPRNINACKVAMMPVYPLV 355          
BLAST of Cathepsin L vs. Planmine SMEST
Match: SMESG000063471.1 (SMESG000063471.1)

HSP 1 Score: 630.172 bits (1624), Expect = 0.000e+0
Identity = 312/355 (87.89%), Postives = 333/355 (93.80%), Query Frame = 2
Query:    2 MGPILICLLLAVISEARTTYSHHKSVPSDDISSKFELENMVSLLSRYDGEFQTFKQRYNKSYSSMHEENSRFLNFISSLLEINHHNQLYENGQKSYEIGINHLSDWSGEELAQLTKLKQSNLTGSSYLSSNVKIDLPDSFDWREKGAVTEVKNQGFCGSCYAFATTGTLEAQIWRKTGKLISLSEQQIVXXXXXXXXXXXXFVQDALSYIKSNGGIENEESYPYISSETFKPNSKCNFFKSKVVATDTGFVQMPANDETKMKEALVTIGPISVAISATKSLKRYTSGIFHEDECDKLKLNHAVLIVGYGTDQTSGTPYWIIKNSWSSFWGENGYFRLPRNINACKVAMMPVYPLV 1066
            M PILICLLLAVISEARTTYSHHKSVPSDDISSKFELENMVSLLSRYDGEFQTFKQRYNKSYSSMHEENSRFLNFISSLLEINHHNQLYENGQKSYEIGINHLSDWS EEL+QLTKLKQSNLTGSSYLSS+VKIDLPDSFDWREKGAVTEVK+QG CGSCYAFA TGTLEAQIWRKTGKLISLSEQQIVDCDTND+ C GGFVQDALSYIKSNGGIENEE+YPY+S +T   N KCNF KSKVVATDTGFV+MPANDE K+KEALVTIGPIS  +SA KSL +Y+ GIF++ EC+KL++NHAVLIVGYGTDQTSGTPYWIIKNSW++ WGE GYFRLPRNINACK+A +PVYPLV
Sbjct:    1 MSPILICLLLAVISEARTTYSHHKSVPSDDISSKFELENMVSLLSRYDGEFQTFKQRYNKSYSSMHEENSRFLNFISSLLEINHHNQLYENGQKSYEIGINHLSDWSDEELSQLTKLKQSNLTGSSYLSSSVKIDLPDSFDWREKGAVTEVKDQGKCGSCYAFAATGTLEAQIWRKTGKLISLSEQQIVDCDTNDNNCYGGFVQDALSYIKSNGGIENEENYPYVSGKTADMNPKCNFVKSKVVATDTGFVKMPANDEEKLKEALVTIGPISALLSAPKSLIKYSKGIFYDKECEKLRVNHAVLIVGYGTDQTSGTPYWIIKNSWNASWGEKGYFRLPRNINACKIASVPVYPLV 355          
BLAST of Cathepsin L vs. Planmine SMEST
Match: SMESG000063471.1 (SMESG000063471.1)

HSP 1 Score: 629.787 bits (1623), Expect = 0.000e+0
Identity = 312/355 (87.89%), Postives = 333/355 (93.80%), Query Frame = 2
Query:    2 MGPILICLLLAVISEARTTYSHHKSVPSDDISSKFELENMVSLLSRYDGEFQTFKQRYNKSYSSMHEENSRFLNFISSLLEINHHNQLYENGQKSYEIGINHLSDWSGEELAQLTKLKQSNLTGSSYLSSNVKIDLPDSFDWREKGAVTEVKNQGFCGSCYAFATTGTLEAQIWRKTGKLISLSEQQIVXXXXXXXXXXXXFVQDALSYIKSNGGIENEESYPYISSETFKPNSKCNFFKSKVVATDTGFVQMPANDETKMKEALVTIGPISVAISATKSLKRYTSGIFHEDECDKLKLNHAVLIVGYGTDQTSGTPYWIIKNSWSSFWGENGYFRLPRNINACKVAMMPVYPLV 1066
            M PILICLLLAVISEARTTYSHHKSVPSDDISSKFELENMVSLLSRYDGEFQTFKQRYNKSYSSMHEENSRFLNFISSLLEINHHNQLYENGQKSYEIGINHLSDWS EEL+QLTKLKQSNLTGSSYLSS+VKIDLPDSFDWREKGAVTEVK+QG CGSCYAFA TGTLEAQIWRKTGKLISLSEQQIVDCDTND+ C GGFVQDALSYIKSNGGIENEE+YPY+S +T   N KCNF KSKVVATDTGFV+MPANDE K+KEALVTIGPIS  +SA KSL +Y+ GIF++ EC+KL++NHAVLIVGYGTDQTSGTPYWIIKNSW++ WGE GYFRLPRNINACK+A +PVYPLV
Sbjct:    4 MSPILICLLLAVISEARTTYSHHKSVPSDDISSKFELENMVSLLSRYDGEFQTFKQRYNKSYSSMHEENSRFLNFISSLLEINHHNQLYENGQKSYEIGINHLSDWSDEELSQLTKLKQSNLTGSSYLSSSVKIDLPDSFDWREKGAVTEVKDQGKCGSCYAFAATGTLEAQIWRKTGKLISLSEQQIVDCDTNDNNCYGGFVQDALSYIKSNGGIENEENYPYVSGKTADMNPKCNFVKSKVVATDTGFVKMPANDEEKLKEALVTIGPISALLSAPKSLIKYSKGIFYDKECEKLRVNHAVLIVGYGTDQTSGTPYWIIKNSWNASWGEKGYFRLPRNINACKIASVPVYPLV 358          
BLAST of Cathepsin L vs. Planmine SMEST
Match: SMESG000034294.1 (SMESG000034294.1)

HSP 1 Score: 397.512 bits (1020), Expect = 3.670e-138
Identity = 194/314 (61.78%), Postives = 238/314 (75.80%), Query Frame = 2
Query:  125 SLLSRYDGEFQTFKQRYNKSYSSMHEENSRFLNFISSLLEINHHNQLYENGQKSYEIGINHLSDWSGEELAQLTKLKQSNLTGSSYLSSNVKIDLPDSFDWREKGAVTEVKNQGFCGSCYAFATTGTLEAQIWRKTGKLISLSEQQIVXXXXXXXXXXXXFVQDALSYIKSNGGIENEESYPYISSETFKPNSKCNFFKSKVVATDTGFVQMPANDETKMKEALVTIGPISVAISATKSLKRYTSGIFHEDECDKLKLNHAVLIVGYGTDQTSGTPYWIIKNSWSSFWGENGYFRLPRNINACKVAMMPVYPLV 1066
            SL+  +  EF  FK++Y K Y S+ EEN RF NFI S +EIN+HNQ++E G K +++ INH+SDW+ EE  QL  LK SNL GS+YL  N+K DLP+SFDWR+KGAVTEVKNQ +CGSCYAF+TTG LE Q++RKTG LISLSEQQIVDCD  D GC GG V DA +YIK +GGIE+E+ YPY+S  T KPN  CNF + K V TDTGFV++P  DE  ++EALVTIGPIS+A SAT+  K Y +GI+H+D C  +++NH VL+VGYGTD+ SGTPYWIIKNSW   WGE+GYFR  RN N C +A    YPLV
Sbjct:   46 SLMVDFKSEFAKFKRQYGKVYESVEEENERFNNFILSQVEINNHNQMFEKGHKKFQMEINHMSDWTQEEFNQLNSLKISNLNGSTYLPLNIKPDLPESFDWRDKGAVTEVKNQKYCGSCYAFSTTGALEGQLFRKTGNLISLSEQQIVDCDHVDYGCSGGLVPDAFNYIKYSGGIESEQEYPYVSGLTKKPNPNCNFKEKKAVGTDTGFVKLPPGDEEALREALVTIGPISIAFSATEQFKHYKNGIYHDDWCSNVRINHGVLLVGYGTDEESGTPYWIIKNSWGPKWGESGYFRFERNKNMCNMAYNSYYPLV 359          
The following BLAST results are available for this feature:
BLAST of Cathepsin L vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
CTSV3.369e-6537.31cathepsin V [Source:HGNC Symbol;Acc:HGNC:2538][more]
CTSV3.369e-6537.31cathepsin V [Source:HGNC Symbol;Acc:HGNC:2538][more]
CTSL3.607e-6539.37cathepsin L [Source:HGNC Symbol;Acc:HGNC:2537][more]
CTSL3.607e-6539.37cathepsin L [Source:HGNC Symbol;Acc:HGNC:2537][more]
CTSS3.283e-6441.38cathepsin S [Source:HGNC Symbol;Acc:HGNC:2545][more]
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BLAST of Cathepsin L vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
cpl-11.488e-7741.72CathePsin L family [Source:UniProtKB/TrEMBL;Acc:H... [more]
tag-1961.998e-5640.32pep chromosome:WBcel235:V:8594914:8597500:1 gene:W... [more]
tag-1961.998e-5640.32pep chromosome:WBcel235:V:8594914:8597469:1 gene:W... [more]
cpl-11.983e-5549.02CathePsin L family [Source:UniProtKB/TrEMBL;Acc:H... [more]
cpl-11.983e-5549.02CathePsin L family [Source:UniProtKB/TrEMBL;Acc:H... [more]
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BLAST of Cathepsin L vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Cp16.870e-7942.37gene:FBgn0013770 transcript:FBtr0087592[more]
Cp11.252e-7842.37gene:FBgn0013770 transcript:FBtr0087593[more]
Cp12.569e-7641.64gene:FBgn0013770 transcript:FBtr0339955[more]
Cp15.637e-7047.39gene:FBgn0013770 transcript:FBtr0304021[more]
CG48474.422e-6740.18gene:FBgn0034229 transcript:FBtr0086934[more]
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BLAST of Cathepsin L vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ctsl.12.969e-7743.65cathepsin L.1 [Source:ZFIN;Acc:ZDB-GENE-040718-61][more]
ctsl.12.969e-7743.65cathepsin L.1 [Source:ZFIN;Acc:ZDB-GENE-040718-61][more]
ctsl.12.969e-7743.65cathepsin L.1 [Source:ZFIN;Acc:ZDB-GENE-040718-61][more]
ctsla6.715e-7340.12cathepsin La [Source:ZFIN;Acc:ZDB-GENE-030131-106][more]
ctsla6.715e-7340.12cathepsin La [Source:ZFIN;Acc:ZDB-GENE-030131-106][more]
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BLAST of Cathepsin L vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
fcrl29.580e-7141.46Fc receptor-like 2 [Source:Xenbase;Acc:XB-GENE-590... [more]
fcrl21.138e-7041.46Fc receptor-like 2 [Source:Xenbase;Acc:XB-GENE-590... [more]
ctsk2.360e-6637.22cathepsin K (pycnodysostosis) [Source:NCBI gene;Ac... [more]
ctsk2.763e-6637.22cathepsin K (pycnodysostosis) [Source:NCBI gene;Ac... [more]
harbi13.074e-6439.17harbinger transposase derived 1 [Source:Xenbase;Ac... [more]
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BLAST of Cathepsin L vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Ctsk3.597e-7039.39cathepsin K [Source:MGI Symbol;Acc:MGI:107823][more]
Ctsl2.024e-6739.87cathepsin L [Source:MGI Symbol;Acc:MGI:88564][more]
Ctsl2.024e-6739.87cathepsin L [Source:MGI Symbol;Acc:MGI:88564][more]
4930486L24Rik8.982e-6536.51RIKEN cDNA 4930486L24 gene [Source:MGI Symbol;Acc:... [more]
Ctss8.663e-6339.94cathepsin S [Source:MGI Symbol;Acc:MGI:107341][more]
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BLAST of Cathepsin L vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q26636|CATL_SARPE2.215e-8343.94Cathepsin L OS=Sarcophaga peregrina OX=7386 PE=1 S... [more]
sp|Q95029|CATL_DROME1.255e-7742.37Cathepsin L OS=Drosophila melanogaster OX=7227 GN=... [more]
sp|O45734|CPL1_CAEEL1.893e-7641.72Cathepsin L-like OS=Caenorhabditis elegans OX=6239... [more]
sp|P13277|CYSP1_HOMAM1.261e-6940.00Digestive cysteine proteinase 1 OS=Homarus america... [more]
sp|P55097|CATK_MOUSE2.516e-6939.39Cathepsin K OS=Mus musculus OX=10090 GN=Ctsk PE=1 ... [more]
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BLAST of Cathepsin L vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A267GB112.728e-8643.05Uncharacterized protein OS=Macrostomum lignano OX=... [more]
A0A267DZX32.879e-8643.05Uncharacterized protein OS=Macrostomum lignano OX=... [more]
A0A1I8J1307.470e-8544.44Uncharacterized protein OS=Macrostomum lignano OX=... [more]
A0A1I8IYR51.001e-8444.44Uncharacterized protein OS=Macrostomum lignano OX=... [more]
K1R5E76.076e-8447.00Cathepsin L OS=Crassostrea gigas OX=29159 GN=CGI_1... [more]
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BLAST of Cathepsin L vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSAMXT00000040914.11.923e-8245.08pep primary_assembly:Astyanax_mexicanus-2.0:APWO02... [more]
ENSAMXT00000001970.21.865e-7944.34cathepsin L1-like [Source:NCBI gene;Acc:103022163][more]
ctsl.15.099e-7844.34cathepsin L1-like [Source:NCBI gene;Acc:103023607][more]
ENSAMXT00000047972.15.525e-7742.32pep primary_assembly:Astyanax_mexicanus-2.0:APWO02... [more]
ENSAMXT00000034892.13.924e-7543.40cathepsin L1-like [Source:NCBI gene;Acc:107196839][more]
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BLAST of Cathepsin L vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSPMAT00000006499.11.662e-6839.62pep scaffold:Pmarinus_7.0:GL477089:42202:47941:1 g... [more]
ENSPMAT00000010475.11.674e-6741.67pep scaffold:Pmarinus_7.0:GL482653:10321:33550:-1 ... [more]
ENSPMAT00000003800.11.778e-6741.33pep scaffold:Pmarinus_7.0:GL485125:12828:20107:1 g... [more]
ENSPMAT00000011285.17.740e-6639.67pep scaffold:Pmarinus_7.0:GL499136:454:1347:-1 gen... [more]
ENSPMAT00000007755.15.621e-6039.75pep scaffold:Pmarinus_7.0:GL476381:1843:17023:-1 g... [more]
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BLAST of Cathepsin L vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Cathepsin L vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO458521.150e-7843.15Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO367276.859e-7343.67Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO459531.570e-6840.69Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO464659.703e-6839.06Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO427511.781e-5248.85Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Cathepsin L vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ctsl.19.973e-7541.85cathepsin L1 [Source:NCBI gene;Acc:101171789][more]
ctsl1.239e-7039.51cathepsin L [Source:NCBI gene;Acc:100049246][more]
ctss2.11.981e-6439.50cathepsin S [Source:NCBI gene;Acc:101165175][more]
ctsk1.657e-6338.34cathepsin K [Source:NCBI gene;Acc:101164922][more]
cts125.449e-6240.13cathepsin L1-like [Source:NCBI gene;Acc:101170830][more]
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BLAST of Cathepsin L vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000063517.10.000e+0100.00SMESG000063517.1[more]
SMESG000063517.10.000e+0100.00SMESG000063517.1[more]
SMESG000063471.10.000e+087.89SMESG000063471.1[more]
SMESG000063471.10.000e+087.89SMESG000063471.1[more]
SMESG000034294.13.670e-13861.78SMESG000034294.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30017650 ID=SMED30017650|Name=Cathepsin L|organism=Schmidtea mediterranea sexual|type=transcript|length=1091bp
GATGGGTCCTATCTTGATATGTTTATTATTAGCAGTGATTTCAGAAGCCA
GAACCACTTATAGCCATCACAAATCAGTTCCAAGTGATGACATTTCTAGT
AAATTTGAACTAGAAAATATGGTATCTCTCTTGTCCCGTTACGATGGAGA
ATTCCAAACCTTCAAACAGCGATATAATAAATCTTATAGTTCCATGCATG
AAGAGAATTCCAGATTTTTAAATTTTATATCATCTCTACTTGAGATCAAT
CATCACAATCAACTTTATGAAAACGGTCAGAAATCATACGAGATTGGAAT
CAACCATTTGAGTGATTGGAGTGGCGAAGAACTCGCTCAACTGACTAAAT
TGAAACAATCAAACCTGACGGGCTCATCATATCTATCATCCAATGTGAAA
ATTGACCTTCCAGATTCATTCGACTGGAGAGAGAAAGGTGCAGTTACTGA
AGTAAAAAACCAAGGATTTTGTGGATCATGTTATGCATTTGCTACTACTG
GCACCCTAGAAGCCCAAATCTGGAGGAAGACTGGGAAATTGATCAGTTTA
TCAGAACAACAAATTGTTGATTGCGATACTAATGATGATGGTTGTGATGG
CGGATTTGTGCAAGACGCGTTATCATACATCAAGTCAAATGGAGGCATTG
AAAATGAGGAAAGTTACCCTTACATATCAAGTGAAACATTTAAACCTAAT
TCTAAATGCAATTTCTTCAAAAGCAAAGTAGTGGCCACCGACACTGGATT
CGTTCAAATGCCAGCAAATGACGAAACAAAAATGAAAGAAGCTCTAGTTA
CAATTGGGCCTATTTCAGTAGCAATATCTGCAACCAAATCGCTCAAAAGA
TATACAAGTGGCATTTTTCATGAGGATGAATGTGACAAACTAAAACTTAA
TCACGCTGTTCTGATAGTCGGATATGGAACAGATCAAACTTCCGGGACAC
CATATTGGATAATTAAAAATAGTTGGAGCTCATTTTGGGGAGAAAATGGA
TATTTCCGGTTACCCAGAAATATAAATGCTTGCAAAGTAGCGATGATGCC
AGTTTATCCTTTGGTTTGAATTGATAAAATTTTGTTCACAC
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protein sequence of SMED30017650-orf-1

>SMED30017650-orf-1 ID=SMED30017650-orf-1|Name=SMED30017650-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=356bp
MGPILICLLLAVISEARTTYSHHKSVPSDDISSKFELENMVSLLSRYDGE
FQTFKQRYNKSYSSMHEENSRFLNFISSLLEINHHNQLYENGQKSYEIGI
NHLSDWSGEELAQLTKLKQSNLTGSSYLSSNVKIDLPDSFDWREKGAVTE
VKNQGFCGSCYAFATTGTLEAQIWRKTGKLISLSEQQIVDCDTNDDGCDG
GFVQDALSYIKSNGGIENEESYPYISSETFKPNSKCNFFKSKVVATDTGF
VQMPANDETKMKEALVTIGPISVAISATKSLKRYTSGIFHEDECDKLKLN
HAVLIVGYGTDQTSGTPYWIIKNSWSSFWGENGYFRLPRNINACKVAMMP
VYPLV*
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Aliases
The feature 'Cathepsin L' has the following synonyms
Synonym
Smed_04497
Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000418head
PLANA:0002075pigment cell
Vocabulary: INTERPRO
TermDefinition
IPR039417Peptidase_C1A_papain-like
IPR038765Papain-like_cys_pep_sf
IPR000668Peptidase_C1A_C
IPR013201Prot_inhib_I29
IPR025660Pept_his_AS
IPR000169Pept_cys_AS
IPR025661Pept_asp_AS
Vocabulary: molecular function
TermDefinition
GO:0008234cysteine-type peptidase activity
GO:0008233peptidase activity
GO:0016787hydrolase activity
Vocabulary: biological process
TermDefinition
GO:0006508proteolysis
GO:0007275multicellular organism development
GO:0030154cell differentiation
Vocabulary: cellular component
TermDefinition
GO:0005764lysosome
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000668Peptidase C1A, papain C-terminalPRINTSPR00705PAPAINcoord: 301..311
score: 62.49
coord: 318..324
score: 75.14
coord: 154..169
score: 55.44
IPR000668Peptidase C1A, papain C-terminalSMARTSM00645pept_c1coord: 136..354
e-value: 2.4E-106
score: 369.3
IPR000668Peptidase C1A, papain C-terminalPFAMPF00112Peptidase_C1coord: 136..353
e-value: 5.1E-77
score: 258.8
IPR013201Cathepsin propeptide inhibitor domain (I29)SMARTSM00848Inhibitor_I29_2coord: 51..111
e-value: 1.3E-18
score: 77.8
IPR013201Cathepsin propeptide inhibitor domain (I29)PFAMPF08246Inhibitor_I29coord: 51..110
e-value: 1.6E-11
score: 44.5
NoneNo IPR availableGENE3DG3DSA:3.90.70.10coord: 45..355
e-value: 1.2E-106
score: 358.9
NoneNo IPR availablePANTHERPTHR12411:SF631coord: 46..354
NoneNo IPR availablePANTHERPTHR12411CYSTEINE PROTEASE FAMILY C1-RELATEDcoord: 46..354
NoneNo IPR availableSIGNALP_EUKSignalP-noTMSignalP-noTMcoord: 1..16
score: 0.746
IPR025660Cysteine peptidase, histidine active sitePROSITEPS00639THIOL_PROTEASE_HIScoord: 299..309
IPR000169Cysteine peptidase, cysteine active sitePROSITEPS00139THIOL_PROTEASE_CYScoord: 154..165
IPR025661Cysteine peptidase, asparagine active sitePROSITEPS00640THIOL_PROTEASE_ASNcoord: 318..337
IPR039417Papain-like cysteine endopeptidaseCDDcd02248Peptidase_C1Acoord: 137..353
e-value: 2.61001E-112
score: 323.807
IPR038765Papain-like cysteine peptidase superfamilySUPERFAMILYSSF54001Cysteine proteinasescoord: 48..354