TNF receptor-associated factor
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30017619 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 10Note: Hover over icons to view figure legend
Homology
BLAST of TNF receptor-associated factor vs. Ensembl Human
Match: TRAF4 (TNF receptor associated factor 4 [Source:HGNC Symbol;Acc:HGNC:12034]) HSP 1 Score: 122.094 bits (305), Expect = 2.750e-29 Identity = 110/508 (21.65%), Postives = 218/508 (42.91%), Query Frame = 1
Query: 139 MRDYNYESVTEIQNDMLCLLCKKLLVNA-RCAPCSCRFCFTCISDYLDKNEICPGNTEDCKQELLHLN-ENIYVDQPMNIKISKLQVKC--KEMSCDYVDELRKMEEHSRTCKYRSVACPYSNIGCDKC--NISQDKVTDHLQSEIFAHTKLLMDFV-VNFNNEM-----------EMLKANNNGLSAVNELLRNEIN---------------ELKLDG-ERRREEIAELQRKCADQAEEIELLNEDIPALRNVDRNVSDRLDGLQLIIEGNQVAMRAVENDFQQQIAQCATNCQQAEIKQKELIDKIGQMENKQKVDLTEMSNKIDKLSGNVDRKLLEMAANQNQLNYGEFVWKLDKFTDKMADAKNGINAIIYSESFLTHKNGFKMCLRVDPDGFGDGKGTHLSVFFCLMKGEFDGILEWPFRHSVTFALINQR----TRLPHVSRT----AKCADYTNNKELIQSTDRNN-GFGFDQFLSLKELSSNPDLMRNNQIFIKCSVDID 1533
M ++Y+ + + + +LC LC K + + + C RFC TC+ ++L + C ++ L L+ IY D + +++ L ++C E C + LR ++ H TC + + CP ++C +S+ + HLQ + +L +F +F+ E + N G + LL E D + + + L C +Q + ED+P N + L + ++ A+ ++ + K + + + ++Q+ +L E+ ++++LS D G +WK+ + ++ +AK N +S +F THK G+K+ + +G G G+GTHLS++ ++ G FD +LEWPF VTF+L++Q + HV+ T ++ S D ++ GFG+ +F+S +++ + +R++ +FI+ +V++
Sbjct: 1 MPGFDYKFLEKPKRRLLCPLCGKPMREPVQVSTCGHRFCDTCLQEFLSEGVF------KCPEDQLPLDYAKIYPDPELEVQVLGLPIRCIHSEEGCRWSGPLRHLQGHLNTCSFNVIPCP------NRCPMKLSRRDLPAHLQHDC-PKRRLKCEFCGCDFSGEAYESHEGMCPQESVYCENKCGARMMRRLLAQHATSECPKRTQPCTYCTKEFVFDTIQSHQYQCPRLPVACPNQCGVGTVAREDLPGHLKDSCNTALVLCPFKDSGCKHRCPKLAMARHVEESV--------------KPHLAMMCALVSRQRQELQELRRELEELSVGSD---------------GVLIWKIGSYGRRLQEAKAKPNLECFSPAFYTHKYGYKLQVSAFLNGNGSGEGTHLSLYIRVLPGAFDNLLEWPFARRVTFSLLDQSDPGLAKPQHVTETFHPDPNWKNFQKPGTWRGSLDESSLGFGYPKFISHQDIRKR-NYVRDDAVFIRAAVELP 465
BLAST of TNF receptor-associated factor vs. Ensembl Human
Match: TRAF3 (TNF receptor associated factor 3 [Source:HGNC Symbol;Acc:HGNC:12033]) HSP 1 Score: 115.546 bits (288), Expect = 7.848e-27 Identity = 124/528 (23.48%), Postives = 225/528 (42.61%), Query Frame = 1
Query: 148 YNYESVTEIQNDMLCLLCKKLLVNARCAPCSCRFCFTCISDYLDKNEICPGNTEDCKQELLHLNENIYVDQPMNIKISKLQVKCK--------------------------EMSCDYVD----ELRK-MEEH-SRTCKYRSVAC--------------------PYSNIGCD-KCNI--------SQDKVTDHLQSEIFAHTKLLMDFVVNFNNEMEMLKANNNGLSAVNELLRNEINELKLDGERRRE-------EIAELQRKCADQAEEIELLNEDIPALRNVDRNVSDRLDGLQLIIEGNQVAMRAVENDFQQQIAQCATNCQQAEIKQKELIDKIGQMENKQKVDLTEMSNKIDKLSGNVDRKLLEMAANQNQLNYGEFVWKLDKFTDKMADAKNGINAIIYSESFLTHKNGFKMCLRVDPDGFGDGKGTHLSVFFCLMKGEFDGILEWPFRHSVTFALINQRTRLPHVSRTAKCADYTNNKELIQSTDRNNGFGFDQFLSLKELSSNPDLMRNNQIFIKCSVD 1527
Y + V +++ C C +L + + C RFC +C++ L + P T C++ ++ + ++ D +I LQ+ C+ E+ C D LRK + +H + CKYR C P + C KC++ + ++ H S H LL ++ + ++ +L+ + + + L N+I +++ ER++E +I LQR QAE+++ L+++I R + D ++ +E Q + +E+ + Q A N E + + + QM + + L +M + ++LE A+ G +WK+ + + +A G +YS+ F T G+KMC RV +G G GKGTHLS+FF +M+GE+D +L WPF+ VT L++Q + H+ K D ++ + + N G F++ L N ++++ IFIK VD
Sbjct: 39 YKEKFVKTVEDKYKCEKCHLVLCSPKQTECGHRFCESCMAALLSSSS--PKCTA-CQESIV--KDKVFKDNCCKREILALQIYCRNESRGCAEQLMLGHLLVHLKNDCHFEELPCVRPDCKEKVLRKDLRDHVEKACKYREATCSHCKSQVPMIALQKHEDTDCPCVVVSCPHKCSVQTLLRSEGTNQQIKAHEASSAVQHVNLLKEWSNSLEKKVSLLQNESVEKNKSIQSLHNQICSFEIEIERQKEMLRNNESKILHLQRVIDSQAEKLKELDKEIRPFRQN----WEEADSMKSSVESLQNRVTELES-VDKSAGQVARNTGLLESQ----LSRHDQMLSVHDIRLADMDLRF---------QVLETASYN-----GVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLMLMDQGSSRRHLGDAFK-PDPNSSSFKKPTGEMNIASGCPVFVAQTVL-ENGTYIKDDTIFIKVIVD 536
BLAST of TNF receptor-associated factor vs. Ensembl Human
Match: TRAF3 (TNF receptor associated factor 3 [Source:HGNC Symbol;Acc:HGNC:12033]) HSP 1 Score: 115.546 bits (288), Expect = 7.848e-27 Identity = 124/528 (23.48%), Postives = 225/528 (42.61%), Query Frame = 1
Query: 148 YNYESVTEIQNDMLCLLCKKLLVNARCAPCSCRFCFTCISDYLDKNEICPGNTEDCKQELLHLNENIYVDQPMNIKISKLQVKCK--------------------------EMSCDYVD----ELRK-MEEH-SRTCKYRSVAC--------------------PYSNIGCD-KCNI--------SQDKVTDHLQSEIFAHTKLLMDFVVNFNNEMEMLKANNNGLSAVNELLRNEINELKLDGERRRE-------EIAELQRKCADQAEEIELLNEDIPALRNVDRNVSDRLDGLQLIIEGNQVAMRAVENDFQQQIAQCATNCQQAEIKQKELIDKIGQMENKQKVDLTEMSNKIDKLSGNVDRKLLEMAANQNQLNYGEFVWKLDKFTDKMADAKNGINAIIYSESFLTHKNGFKMCLRVDPDGFGDGKGTHLSVFFCLMKGEFDGILEWPFRHSVTFALINQRTRLPHVSRTAKCADYTNNKELIQSTDRNNGFGFDQFLSLKELSSNPDLMRNNQIFIKCSVD 1527
Y + V +++ C C +L + + C RFC +C++ L + P T C++ ++ + ++ D +I LQ+ C+ E+ C D LRK + +H + CKYR C P + C KC++ + ++ H S H LL ++ + ++ +L+ + + + L N+I +++ ER++E +I LQR QAE+++ L+++I R + D ++ +E Q + +E+ + Q A N E + + + QM + + L +M + ++LE A+ G +WK+ + + +A G +YS+ F T G+KMC RV +G G GKGTHLS+FF +M+GE+D +L WPF+ VT L++Q + H+ K D ++ + + N G F++ L N ++++ IFIK VD
Sbjct: 39 YKEKFVKTVEDKYKCEKCHLVLCSPKQTECGHRFCESCMAALLSSSS--PKCTA-CQESIV--KDKVFKDNCCKREILALQIYCRNESRGCAEQLMLGHLLVHLKNDCHFEELPCVRPDCKEKVLRKDLRDHVEKACKYREATCSHCKSQVPMIALQKHEDTDCPCVVVSCPHKCSVQTLLRSEGTNQQIKAHEASSAVQHVNLLKEWSNSLEKKVSLLQNESVEKNKSIQSLHNQICSFEIEIERQKEMLRNNESKILHLQRVIDSQAEKLKELDKEIRPFRQN----WEEADSMKSSVESLQNRVTELES-VDKSAGQVARNTGLLESQ----LSRHDQMLSVHDIRLADMDLRF---------QVLETASYN-----GVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLMLMDQGSSRRHLGDAFK-PDPNSSSFKKPTGEMNIASGCPVFVAQTVL-ENGTYIKDDTIFIKVIVD 536
BLAST of TNF receptor-associated factor vs. Ensembl Human
Match: TRAF3 (TNF receptor associated factor 3 [Source:HGNC Symbol;Acc:HGNC:12033]) HSP 1 Score: 113.235 bits (282), Expect = 6.065e-26 Identity = 95/371 (25.61%), Postives = 171/371 (46.09%), Query Frame = 1
Query: 436 KMEEHSRTCKYRSVACPYSNIGCDKCNISQDKVTDHLQSEIFAHTKLLMDFVVNFNNEMEMLKANNNGLSAVNELLRNEINELKLDGERRRE-------EIAELQRKCADQAEEIELLNEDIPALRNVDRNVSDRLDGLQLIIEGNQVAMRAVENDFQQQIAQCATNCQQAEIKQKELIDKIGQMENKQKVDLTEMSNKIDKLSGNVDRKLLEMAANQNQLNYGEFVWKLDKFTDKMADAKNGINAIIYSESFLTHKNGFKMCLRVDPDGFGDGKGTHLSVFFCLMKGEFDGILEWPFRHSVTFALINQRTRLPHVSRTAKCADYTNNKELIQSTDRNNGFGFDQFLSLKELSSNPDLMRNNQIFIKCSVD 1527
++ H C C + GC +Q ++ H S H LL ++ + ++ +L+ + + + L N+I +++ ER++E +I LQR QAE+++ L+++I R + D ++ +E Q + +E+ + Q A N E + + + QM + + L +M + ++LE A+ G +WK+ + + +A G +YS+ F T G+KMC RV +G G GKGTHLS+FF +M+GE+D +L WPF+ VT L++Q + H+ K D ++ + + N G F++ L N ++++ IFIK VD
Sbjct: 217 ELSAHLSECVNAPSTCSFKRYGCVFQGTNQ-QIKAHEASSAVQHVNLLKEWSNSLEKKVSLLQNESVEKNKSIQSLHNQICSFEIEIERQKEMLRNNESKILHLQRVIDSQAEKLKELDKEIRPFRQN----WEEADSMKSSVESLQNRVTELES-VDKSAGQVARNTGLLESQ----LSRHDQMLSVHDIRLADMDLRF---------QVLETASYN-----GVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLMLMDQGSSRRHLGDAFK-PDPNSSSFKKPTGEMNIASGCPVFVAQTVL-ENGTYIKDDTIFIKVIVD 561
BLAST of TNF receptor-associated factor vs. Ensembl Human
Match: TRAF3 (TNF receptor associated factor 3 [Source:HGNC Symbol;Acc:HGNC:12033]) HSP 1 Score: 113.235 bits (282), Expect = 6.065e-26 Identity = 95/371 (25.61%), Postives = 171/371 (46.09%), Query Frame = 1
Query: 436 KMEEHSRTCKYRSVACPYSNIGCDKCNISQDKVTDHLQSEIFAHTKLLMDFVVNFNNEMEMLKANNNGLSAVNELLRNEINELKLDGERRRE-------EIAELQRKCADQAEEIELLNEDIPALRNVDRNVSDRLDGLQLIIEGNQVAMRAVENDFQQQIAQCATNCQQAEIKQKELIDKIGQMENKQKVDLTEMSNKIDKLSGNVDRKLLEMAANQNQLNYGEFVWKLDKFTDKMADAKNGINAIIYSESFLTHKNGFKMCLRVDPDGFGDGKGTHLSVFFCLMKGEFDGILEWPFRHSVTFALINQRTRLPHVSRTAKCADYTNNKELIQSTDRNNGFGFDQFLSLKELSSNPDLMRNNQIFIKCSVD 1527
++ H C C + GC +Q ++ H S H LL ++ + ++ +L+ + + + L N+I +++ ER++E +I LQR QAE+++ L+++I R + D ++ +E Q + +E+ + Q A N E + + + QM + + L +M + ++LE A+ G +WK+ + + +A G +YS+ F T G+KMC RV +G G GKGTHLS+FF +M+GE+D +L WPF+ VT L++Q + H+ K D ++ + + N G F++ L N ++++ IFIK VD
Sbjct: 217 ELSAHLSECVNAPSTCSFKRYGCVFQGTNQ-QIKAHEASSAVQHVNLLKEWSNSLEKKVSLLQNESVEKNKSIQSLHNQICSFEIEIERQKEMLRNNESKILHLQRVIDSQAEKLKELDKEIRPFRQN----WEEADSMKSSVESLQNRVTELES-VDKSAGQVARNTGLLESQ----LSRHDQMLSVHDIRLADMDLRF---------QVLETASYN-----GVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLMLMDQGSSRRHLGDAFK-PDPNSSSFKKPTGEMNIASGCPVFVAQTVL-ENGTYIKDDTIFIKVIVD 561
BLAST of TNF receptor-associated factor vs. Ensembl Celegans
Match: trf-1 (TNF Receptor Associated Factor (TRAF) homolog; TRF-1 [Source:UniProtKB/TrEMBL;Acc:G5EG80]) HSP 1 Score: 87.4261 bits (215), Expect = 3.838e-18 Identity = 53/173 (30.64%), Postives = 89/173 (51.45%), Query Frame = 1
Query: 1042 KLLEMAANQNQLNYGEFVWKLDKFTDKMADAKNGINAIIYSESFLTHKNGFKM----CLRVDPDGFGDGK--GTHLSVFFCLMKGEFDGILEWPFRHSVTFALINQRTRLPHVSRTAKCADY----TNNKELIQS-TDRNNGFGFDQFLSLKELSSNPDLMRNNQIFIKCSVD 1527
++L A ++ + +WK+DK + +AK+G + I+S F++H+ G+KM CL FGDG G +S++ L+KGEFD LEWPF ++ +L++Q R D N K L + +RN FG F SL L + +++++I+++ VD
Sbjct: 249 RILSAAETCTEMFGPQLIWKIDKLQQRTNEAKSGADTTIFSVPFMSHRFGYKMMACACL------FGDGSSAGKSISLYVLLLKGEFDPTLEWPFHRAIKISLLDQNPRPEDRVNITYVIDPRKLKANEKFLARPRGERNAAFGSQSFCSLAILQ---NYVKDDKIYVQIDVD 412
BLAST of TNF receptor-associated factor vs. Ensembl Celegans
Match: trf-2 (TNF Receptor Associated Factor (TRAF) homolog [Source:UniProtKB/TrEMBL;Acc:Q9N586]) HSP 1 Score: 82.4185 bits (202), Expect = 7.025e-17 Identity = 47/133 (35.34%), Postives = 72/133 (54.14%), Query Frame = 1
Query: 1132 AKNGINAIIYSESFLTHKNGFKMCLRVDPDGFGDGKGTHLSVFFCLMKGEFDGILEWPFRHSVTFALINQRTRLPHVSRTAKCADYTNNKELIQSTD--RNNGFGFDQFLSLKELSSNPDLMRNNQIFIKCSV 1524
KN + IYS+ F +H G+KM P G G + SVF CLMKGE+D ILEWPFR VTF++++ + +++T + +E ++ + RN FGF FL L +++ + + IFI+ V
Sbjct: 175 TKNKSHRSIYSQPFYSHGYGYKMMAVAAPYGDGLAFREYFSVFVCLMKGEWDDILEWPFRCDVTFSILSDDKKE-LLTKTIYVNEMPEIQEFLERPEGLRNGTFGFQNFLPLAKVT---EFAADGDIFIQIKV 303
BLAST of TNF receptor-associated factor vs. Ensembl Fly
Match: Traf4 (gene:FBgn0026319 transcript:FBtr0334401) HSP 1 Score: 91.6633 bits (226), Expect = 2.397e-19 Identity = 51/169 (30.18%), Postives = 92/169 (54.44%), Query Frame = 1
Query: 1042 KLLEMAANQNQLNY-GEFVWKLDKFTDKMADAKNGINAIIYSESFLTHKNGFKMCLRVDPDGFGDGKGTHLSVFFCLMKGEFDGILEWPFRHSVTFALINQRTRLPHVSRTAKCADYTNNKELIQSTDRNN------GFGFDQFLSLKELSSNPDLMRNNQIFIKCSVD 1527
++L+ A ++ +NY G +WK+ ++ KMA+A+ + S F T + G+K+ + +G G G+ TH+SV+ ++ GE+D +L+WPF HS+TF L Q + S A+ ++ R + GFGF +F+S + L S P ++ + +F++ VD
Sbjct: 307 QMLKSAVSKLSINYTGTLLWKITDWSAKMAEARGKDGLELVSPPFYTSQYGYKLQASMFLNGNGPGENTHVSVYIKVLPGEYDALLKWPFSHSITFTLFEQGAQ----SGQGGVAESFVPDPTWENFQRPSNEPDQLGFGFPRFISHELLHSRP-FIKGDTVFLRVKVD 470
BLAST of TNF receptor-associated factor vs. Ensembl Fly
Match: Traf4 (gene:FBgn0026319 transcript:FBtr0077429) HSP 1 Score: 90.8929 bits (224), Expect = 3.498e-19 Identity = 51/169 (30.18%), Postives = 92/169 (54.44%), Query Frame = 1
Query: 1042 KLLEMAANQNQLNY-GEFVWKLDKFTDKMADAKNGINAIIYSESFLTHKNGFKMCLRVDPDGFGDGKGTHLSVFFCLMKGEFDGILEWPFRHSVTFALINQRTRLPHVSRTAKCADYTNNKELIQSTDRNN------GFGFDQFLSLKELSSNPDLMRNNQIFIKCSVD 1527
++L+ A ++ +NY G +WK+ ++ KMA+A+ + S F T + G+K+ + +G G G+ TH+SV+ ++ GE+D +L+WPF HS+TF L Q + S A+ ++ R + GFGF +F+S + L S P ++ + +F++ VD
Sbjct: 316 QMLKSAVSKLSINYTGTLLWKITDWSAKMAEARGKDGLELVSPPFYTSQYGYKLQASMFLNGNGPGENTHVSVYIKVLPGEYDALLKWPFSHSITFTLFEQGAQ----SGQGGVAESFVPDPTWENFQRPSNEPDQLGFGFPRFISHELLHSRP-FIKGDTVFLRVKVD 479
BLAST of TNF receptor-associated factor vs. Ensembl Fly
Match: Traf-like (gene:FBgn0030748 transcript:FBtr0308606) HSP 1 Score: 51.9878 bits (123), Expect = 8.961e-7 Identity = 32/148 (21.62%), Postives = 71/148 (47.97%), Query Frame = 1
Query: 1084 GEFVWKLDKFTDKMADAKNGINAIIYSESFLTHKNGFKMCLRVDPDGFGDGKGTHLSVFFCLMKGEFDGILEWPFRHSVTFALINQRTRLPHVSRTAKCADYTNNKELIQSTDRNNGFGFDQFLSL-KELSSNPDLMRNNQIFIKCSV 1524
G +W++ ++ K+ ++K + I++S F G+ + L + +G G KG ++ ++ GE+D +L WP R + +Q T + A DY K + ++ +Q+ + ++ ++ + +RN+ +FI+ V
Sbjct: 255 GHLIWRIKDYSKKLEESKQ-YDTILHSAMFSNKAFGYALRLDIYLNGKGTWKGRNMIACLNVLSGEYDPLLAWPCRLQAEIIIRDQCTNV------ADAEDYV--KTIFVRKKSDDFIQSNQYFHIPHKVITSRNYLRNDSMFIEVRV 393
BLAST of TNF receptor-associated factor vs. Ensembl Fly
Match: Traf-like (gene:FBgn0030748 transcript:FBtr0074274) HSP 1 Score: 51.9878 bits (123), Expect = 8.961e-7 Identity = 32/148 (21.62%), Postives = 71/148 (47.97%), Query Frame = 1
Query: 1084 GEFVWKLDKFTDKMADAKNGINAIIYSESFLTHKNGFKMCLRVDPDGFGDGKGTHLSVFFCLMKGEFDGILEWPFRHSVTFALINQRTRLPHVSRTAKCADYTNNKELIQSTDRNNGFGFDQFLSL-KELSSNPDLMRNNQIFIKCSV 1524
G +W++ ++ K+ ++K + I++S F G+ + L + +G G KG ++ ++ GE+D +L WP R + +Q T + A DY K + ++ +Q+ + ++ ++ + +RN+ +FI+ V
Sbjct: 255 GHLIWRIKDYSKKLEESKQ-YDTILHSAMFSNKAFGYALRLDIYLNGKGTWKGRNMIACLNVLSGEYDPLLAWPCRLQAEIIIRDQCTNV------ADAEDYV--KTIFVRKKSDDFIQSNQYFHIPHKVITSRNYLRNDSMFIEVRV 393
BLAST of TNF receptor-associated factor vs. Ensembl Fly
Match: Traf-like (gene:FBgn0030748 transcript:FBtr0334036) HSP 1 Score: 51.9878 bits (123), Expect = 8.961e-7 Identity = 32/148 (21.62%), Postives = 71/148 (47.97%), Query Frame = 1
Query: 1084 GEFVWKLDKFTDKMADAKNGINAIIYSESFLTHKNGFKMCLRVDPDGFGDGKGTHLSVFFCLMKGEFDGILEWPFRHSVTFALINQRTRLPHVSRTAKCADYTNNKELIQSTDRNNGFGFDQFLSL-KELSSNPDLMRNNQIFIKCSV 1524
G +W++ ++ K+ ++K + I++S F G+ + L + +G G KG ++ ++ GE+D +L WP R + +Q T + A DY K + ++ +Q+ + ++ ++ + +RN+ +FI+ V
Sbjct: 255 GHLIWRIKDYSKKLEESKQ-YDTILHSAMFSNKAFGYALRLDIYLNGKGTWKGRNMIACLNVLSGEYDPLLAWPCRLQAEIIIRDQCTNV------ADAEDYV--KTIFVRKKSDDFIQSNQYFHIPHKVITSRNYLRNDSMFIEVRV 393
BLAST of TNF receptor-associated factor vs. Ensembl Zebrafish
Match: traf2a (Tnf receptor-associated factor 2a [Source:ZFIN;Acc:ZDB-GENE-071120-2]) HSP 1 Score: 134.035 bits (336), Expect = 3.903e-33 Identity = 118/446 (26.46%), Postives = 200/446 (44.84%), Query Frame = 1
Query: 292 CPGNTEDCK--QELLHLNENIYVDQPMNIKISKLQVKCKEMSCD---YVDELRKMEEHSRTCKYRSVACPYSNIGCDKCNISQDKVTDHLQSEIFAHTKLLMDFVVNFNNEMEMLKANNNGLSA--VNELLRNEINELKLDGERRREEIAELQRKCA----------------------DQAEEIELLNEDIPALRNVDRNVSDRLDGLQLIIEGNQVAMRAVENDFQQQIAQCATNCQQAEIKQKELIDKIGQMENKQKVDLTEMSNKIDKLSGNVDRKLLEMAANQNQLNY----GEFVWKLDKFTDKMADAKNGINAIIYSESFLTHKNGFKMCLRVDPDGFGDGKGTHLSVFFCLMKGEFDGILEWPFRHSVTFALINQRTRLPHVSRTAKCADYTNNKELIQSTDRNNGFGFDQFLSLKELSSNPDLMRNNQIFIKCSVDI 1530
CP T +CK +E H +NI + K + C + YVD H + C C + +GCD + ++K+ DH Q+ + H LL+ F++ +E L+ + L++ ++EL + EL+L + A +Q CA A E++L +E + +S R L+L + + + + + ++ +Q + Q DKI + NK + ++++ G D ++EM A +++ G FVWK+ F+ K DA G ++S +F T K G+KMCLR+ +G G G+GTHLS+FF +M+G D +L+WPF VT L++Q R H+ + D +++ +D N G F L +L S +R++ IFIK VD+
Sbjct: 156 CPERTLNCKYCKEPFHF-KNIKAHDEICPKYPMICEGCAKKKIPREKYVD-------HIKLCTKFRTPCRFHVVGCDM-TVEKEKIHDHEQACSYEHLNLLLHFIMGIKVNLESLQPQSLELASHKIHEL-HQSLRELELKMGQLCGAGASVQGACALPPPPPPAPTLGTSFTPLPTAVGAALELQLHSEKTKVV-----ELSRRCQELELKVNTFENIVCVLNREMERSATTMEAYNRQHRLDQ----DKIEILNNKVR--------QLERTVGLRDLSIVEMEAKMREMSAATYDGVFVWKISDFSKKRQDAVAGRAPAMFSPAFYTSKYGYKMCLRIYLNGDGTGRGTHLSLFFVVMRGHSDALLKWPFNQKVTLMLLDQNNR-EHIIDAFR-PDISSSSFQRPVSDMNIASGCPLFCPLSKLDSKNSYIRDDTIFIKAIVDL 572
BLAST of TNF receptor-associated factor vs. Ensembl Zebrafish
Match: traf4a (tnf receptor-associated factor 4a [Source:ZFIN;Acc:ZDB-GENE-040308-1]) HSP 1 Score: 127.872 bits (320), Expect = 1.773e-31 Identity = 118/501 (23.55%), Postives = 223/501 (44.51%), Query Frame = 1
Query: 139 MRDYNYESVTEIQNDMLCLLCKKLLVNA-RCAPCSCRFCFTCISDYLDKNEICPGNTEDCKQELLHLN-ENIYVDQPMNIKISKLQVKC--KEMSCDYVDELRKMEEHSRTCKYRSVACPYSNIGCDKCNI--SQDKVTDHLQSEIFAHTKLLMDFVVN-FNNEMEMLKANNNGLSAVNELL-RNEINELKLDGERRREEIAELQRKCADQAEEIELLNEDIPALRNVDRNVSDRLDGLQLIIE------GNQ-----VAMRAVENDFQQQIAQCATNCQQAEIKQKELIDKIG---QMENKQKVDLTEMSNKIDKLSGNVDRKLLEMAANQNQLNY---GEFVWKLDKFTDKMADAKNGINAIIYSESFLTHKNGFKMCLRVDPDGFGDGKGTHLSVFFCLMKGEFDGILEWPFRHSVTFALINQR----TRLPHVSRTAKC-ADYTNNKELIQSTDRNN------GFGFDQFLSLKELSSNPDLMRNNQIFIKCSVDID 1533
M ++Y+ + + + C LC K + + + C RFC TC+ ++L + C ++ L L+ IY D + +I L ++C E C + ++++++ H TC + + CP ++C++ ++ + +HLQ + K+ +F + F E N+ G+ + N+ A + R+ Q E P V D + Q NQ +A + N ++ C E K K+ +E K LT M + L G +++LE+ +L+ G +WKL ++ K+ +AK N +S F TH+ G+K+ + +G G G+G+HLS++ ++ GE+D +LEWPF + VTF++++Q ++ H++ T ++ N ++ S RN+ GFG+ +F+S +E+ + +R+N IF+K S++I
Sbjct: 1 MPGFDYKFLEKPKRRFQCPLCSKAMREPVQVSTCGHRFCDTCLQEFLSEGVF------KCPEDQLPLDYAKIYPDPELEQQILALPIRCIHSEEGCRWTGQMKQLQSHFSTCAFNVIPCP------NRCSVKLTRRDLPEHLQHDC-PKRKVKCEFCGSEFTGEA---YENHQGICPQESVYCENKCG-------------ARMMRRLLSQHTMTECPKRTQPCKYCGKEFVYDTIQNHQYHCPRFPVQCPNQCGTPNIAREDLANHVKESCGSALVLCPFKEAGCKHRCPKMAIGRHLEESTKSHLTMMCS----LVGRQRQEILELRREMEELSVSHDGVLIWKLTDYSRKLQEAKLRNNHEFFSPPFYTHRYGYKLQVSAFLNGNGSGEGSHLSIYIRVLPGEYDNLLEWPFSYKVTFSILDQSDPSLSKPQHITETFNPDPNWKNFQKPCSS--RNSLDESTLGFGYPKFISHEEIKKR-NYIRDNSIFLKASIEIP 465
BLAST of TNF receptor-associated factor vs. Ensembl Zebrafish
Match: traf4a (tnf receptor-associated factor 4a [Source:ZFIN;Acc:ZDB-GENE-040308-1]) HSP 1 Score: 127.872 bits (320), Expect = 1.773e-31 Identity = 118/501 (23.55%), Postives = 223/501 (44.51%), Query Frame = 1
Query: 139 MRDYNYESVTEIQNDMLCLLCKKLLVNA-RCAPCSCRFCFTCISDYLDKNEICPGNTEDCKQELLHLN-ENIYVDQPMNIKISKLQVKC--KEMSCDYVDELRKMEEHSRTCKYRSVACPYSNIGCDKCNI--SQDKVTDHLQSEIFAHTKLLMDFVVN-FNNEMEMLKANNNGLSAVNELL-RNEINELKLDGERRREEIAELQRKCADQAEEIELLNEDIPALRNVDRNVSDRLDGLQLIIE------GNQ-----VAMRAVENDFQQQIAQCATNCQQAEIKQKELIDKIG---QMENKQKVDLTEMSNKIDKLSGNVDRKLLEMAANQNQLNY---GEFVWKLDKFTDKMADAKNGINAIIYSESFLTHKNGFKMCLRVDPDGFGDGKGTHLSVFFCLMKGEFDGILEWPFRHSVTFALINQR----TRLPHVSRTAKC-ADYTNNKELIQSTDRNN------GFGFDQFLSLKELSSNPDLMRNNQIFIKCSVDID 1533
M ++Y+ + + + C LC K + + + C RFC TC+ ++L + C ++ L L+ IY D + +I L ++C E C + ++++++ H TC + + CP ++C++ ++ + +HLQ + K+ +F + F E N+ G+ + N+ A + R+ Q E P V D + Q NQ +A + N ++ C E K K+ +E K LT M + L G +++LE+ +L+ G +WKL ++ K+ +AK N +S F TH+ G+K+ + +G G G+G+HLS++ ++ GE+D +LEWPF + VTF++++Q ++ H++ T ++ N ++ S RN+ GFG+ +F+S +E+ + +R+N IF+K S++I
Sbjct: 1 MPGFDYKFLEKPKRRFQCPLCSKAMREPVQVSTCGHRFCDTCLQEFLSEGVF------KCPEDQLPLDYAKIYPDPELEQQILALPIRCIHSEEGCRWTGQMKQLQSHFSTCAFNVIPCP------NRCSVKLTRRDLPEHLQHDC-PKRKVKCEFCGSEFTGEA---YENHQGICPQESVYCENKCG-------------ARMMRRLLSQHTMTECPKRTQPCKYCGKEFVYDTIQNHQYHCPRFPVQCPNQCGTPNIAREDLANHVKESCGSALVLCPFKEAGCKHRCPKMAIGRHLEESTKSHLTMMCS----LVGRQRQEILELRREMEELSVSHDGVLIWKLTDYSRKLQEAKLRNNHEFFSPPFYTHRYGYKLQVSAFLNGNGSGEGSHLSIYIRVLPGEYDNLLEWPFSYKVTFSILDQSDPSLSKPQHITETFNPDPNWKNFQKPCSS--RNSLDESTLGFGYPKFISHEEIKKR-NYIRDNSIFLKASIEIP 465
BLAST of TNF receptor-associated factor vs. Ensembl Zebrafish
Match: BX901915.1 (pep chromosome:GRCz11:CHR_ALT_CTG5_1_18:28764891:28768979:-1 gene:ENSDARG00000109857.1 transcript:ENSDART00000191629.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:BX901915.1) HSP 1 Score: 117.857 bits (294), Expect = 1.979e-29 Identity = 78/242 (32.23%), Postives = 125/242 (51.65%), Query Frame = 1
Query: 883 FQQQIAQCATNCQQAEIK-----------QKELIDKIGQME--NKQ------KVDLTEMSNKIDKLSGNV---DRKLLEMAANQNQLNY----GEFVWKLDKFTDKMADAKNGINAIIYSESFLTHKNGFKMCLRVDPDGFGDGKGTHLSVFFCLMKGEFDGILEWPFRHSVTFALINQRTRLPHVSRTAKCADYTNNKELIQSTDRNNGFGFDQFLSLKELSSNPDLMRNNQIFIKCSVDI 1530
Q Q+ + + CQ+ E+K +E+ ME N+Q K+++ ++NK+ +L V D ++EM A +++ G FVWK+ F+ K DA G ++S +F T K G+KMCLR+ +G G G+GTHLS+FF +M+G D +L+WPF VT L++Q R H+ + D +++ +D N G F L +L S +R++ IFIK VD+
Sbjct: 35 LQPQMVELSRRCQELELKVNTFENIVCVLNREMERSATTMEAYNRQHRLDQDKIEI--LNNKVRQLERTVGLRDLSIVEMEAKMREMSAATYDGVFVWKISDFSKKRQDAVAGRAPAMFSPAFYTSKYGYKMCLRIYLNGDGTGRGTHLSLFFVVMRGHSDALLKWPFNQKVTLMLLDQNNR-EHIIDAFR-PDISSSSFQRPVSDMNIASGCPLFCPLSKLDSKNSYIRDDTIFIKAIVDL 272
BLAST of TNF receptor-associated factor vs. Ensembl Zebrafish
Match: AL844899.1 (pep chromosome:GRCz11:CHR_ALT_CTG5_2_4:28756846:28760787:-1 gene:ENSDARG00000111038.1 transcript:ENSDART00000183806.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:AL844899.1) HSP 1 Score: 117.857 bits (294), Expect = 1.979e-29 Identity = 78/242 (32.23%), Postives = 125/242 (51.65%), Query Frame = 1
Query: 883 FQQQIAQCATNCQQAEIK-----------QKELIDKIGQME--NKQ------KVDLTEMSNKIDKLSGNV---DRKLLEMAANQNQLNY----GEFVWKLDKFTDKMADAKNGINAIIYSESFLTHKNGFKMCLRVDPDGFGDGKGTHLSVFFCLMKGEFDGILEWPFRHSVTFALINQRTRLPHVSRTAKCADYTNNKELIQSTDRNNGFGFDQFLSLKELSSNPDLMRNNQIFIKCSVDI 1530
Q Q+ + + CQ+ E+K +E+ ME N+Q K+++ ++NK+ +L V D ++EM A +++ G FVWK+ F+ K DA G ++S +F T K G+KMCLR+ +G G G+GTHLS+FF +M+G D +L+WPF VT L++Q R H+ + D +++ +D N G F L +L S +R++ IFIK VD+
Sbjct: 35 LQPQMVELSRRCQELELKVNTFENIVCVLNREMERSATTMEAYNRQHRLDQDKIEI--LNNKVRQLERTVGLRDLSIVEMEAKMREMSAATYDGVFVWKISDFSKKRQDAVAGRAPAMFSPAFYTSKYGYKMCLRIYLNGDGTGRGTHLSLFFVVMRGHSDALLKWPFNQKVTLMLLDQNNR-EHIIDAFR-PDISSSSFQRPVSDMNIASGCPLFCPLSKLDSKNSYIRDDTIFIKAIVDL 272
BLAST of TNF receptor-associated factor vs. Ensembl Xenopus
Match: ssh2 (slingshot protein phosphatase 2 [Source:Xenbase;Acc:XB-GENE-993093]) HSP 1 Score: 124.79 bits (312), Expect = 5.580e-30 Identity = 132/523 (25.24%), Postives = 234/523 (44.74%), Query Frame = 1
Query: 148 YNYESVTEIQNDMLCLLCKKLLVNARCAPCSCRFCFTCISDYLDKNE----ICPGN-TED-------CKQELLHL-----NENIYVDQPMNIK--ISKLQVKCK--EMSCDYVD----ELRK-MEEH-SRTCKYRS--------------------VACPYSNIGCDK-CNI--------SQDKVTDHLQSEIFAHTKLLMDFVVNFNNEMEMLKANNNGLSAVNELLRNEINELKLDGERRREE-------IAELQRKCADQAEEIELLNEDIPALRNVDRNVSDRLDGLQLIIEGNQVAMRAVENDFQQQIAQCATNCQQAEIKQKELIDKIGQMENKQKVDLTEMSNKIDKLSGNVDRKLLEMAANQNQLNYGEFVWKLDKFTDKMADAKNGINAIIYSESFLTHKNGFKMCLRVDPDGFGDGKGTHLSVFFCLMKGEFDGILEWPFRHSVTFALINQRTRLPHVSRTAKCADYTNNKELIQSTDRNNGFGFDQFLSLKELSSNPDLMRNNQIFIKCSVD 1527
Y + ++ C C+ +L N R C RFC TC++ L C N T+D C++E+L L NE + + + + L+ C+ E+SC D +RK + +H +TCKYR V CP I C C++ + ++ H S H L+ ++ ++ ML+ ++ + ++L N++ +++ ER +E+ I +LQR QA++++ L+++I RN+ R D DG++ E Q + +E +A+ A + ++ + I++ QM + + L +M + ++LE A+ G +WK+ + + +A G +YS+ F T G+KMC RV +G G GKGTHLS+FF +M+GE+D +L WPF+ V+ L++Q H+ K D ++ + + N G F++ L N ++++ IFIK VD
Sbjct: 34 YKERFLKPVEEKYKCEKCRLVLCNPRQTECGHRFCETCMNAILSSTSPQCMACEDNITKDKVFKDNCCRREVLALQMFCRNETRGCKELITLGNLLIHLKSDCQFEELSCPRADCKEKVIRKDLSDHIEKTCKYRETPCKFCRNQVPLVEMQKHEDVDCPSVVISCPHMCSVKSLLRSEGTNQQIKAHEASSAVQHVNLMKEWSNYLEAKVSMLQNESSEKNKSIQILHNQMCSFEIEIERHKEQLRNNEARIIQLQRVIEGQADKLKDLDKEI---RNL-RQTGDEADGMKSNYESLQNRLSQLE-----VMAKNAASWNPGVLETQ--INRHDQMLSVHDIRLADMDLRF---------QVLETASYN-----GVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVSLMLMDQGPSRRHLGDAFK-PDPNSSSFKKPTGEMNIASGCPVFVAQTVL-ENGTYIKDDTIFIKVIVD 529
BLAST of TNF receptor-associated factor vs. Ensembl Xenopus
Match: sytl2 (synaptotagmin like 2 [Source:Xenbase;Acc:XB-GENE-945155]) HSP 1 Score: 118.242 bits (295), Expect = 4.720e-28 Identity = 106/509 (20.83%), Postives = 220/509 (43.22%), Query Frame = 1
Query: 139 MRDYNYESVTEIQNDMLCLLCKKLLVNA-RCAPCSCRFCFTCISDYLDKNEICPGNTEDCKQELLHLN-ENIYVDQPMNIKISKLQVKC--KEMSCDYVDELRKMEEHSRTCKYRSVA---------------------CPYSNIGCDKC--NISQDKVTDH----LQSEIFAHTKL---LMDFVVNFNNEMEMLKANNNGLSAVNELLRNEINELKLDGERRREEIAELQRKCADQAEEIELLNEDIPALRNVDRNVSDRLDGLQLIIEGNQVAMRAVENDFQQQIAQCATNCQQAEIKQKELIDKIGQMENKQKVDLTEMSNKIDKLSGNVDRKLLEMAANQNQLNYGEFVWKLDKFTDKMADAKNGINAIIYSESFLTHKNGFKMCLRVDPDGFGDGKGTHLSVFFCLMKGEFDGILEWPFRHSVTFALINQR----TRLPHVSRTAKCADYTNNKELIQSTDRNN-------GFGFDQFLSLKELSSNPDLMRNNQIFIKCSVDI 1530
M Y+Y+ + +++ LC LC K + + + C RFC TC+ ++L + C ++ L L+ IY D+ + ++ L ++C E C + +L++++ H C + + CP + C+ C + + + DH Q ++ K +M V++ ++ +E K E + + I + R C +Q + ED+ ++ D + + + ++ + T + E + + + + ++Q+ ++ E+ ++++LS + + G +WK+ ++ K+ +AK N +S F THK G+K+ + +G G G+G++LSV+ ++ GE+D +LEWPF + VTF+L++Q ++ H++ T N K + T N GFG+ +F+S +++ + +R+N IF++ SV+I
Sbjct: 1 MPGYDYKFLEKLRRKFLCPLCGKAMREPVQVSTCGHRFCDTCLQEFLSEGVF------KCPEDQLPLDYAKIYPDRDLETQVMGLSIRCIHSEEGCRWSGQLKQLQPHLNICAFNVIPCPNRCSTKLIRRDLPEHMQHDCPKRKVRCEFCGADFTGEAYEDHQGCCPQESVYCENKCGARMMRRVLSQHSLVECPKRTQPCPYCNKEFVFDTIQSHQYQCPR-------YPTPCPNQCGIASIAREDL------SNHLKDSCS--------SALVLCPFKDSGCKHRGPKITISRHLEENMRAHLSMMSSLVSRQRQEILELRKQVEELSVSSE---------------GVLIWKISDYSRKVQEAKVRGNFESFSPPFYTHKYGYKLQVSAFLNGNGSGEGSYLSVYIRVLPGEYDNLLEWPFSYRVTFSLLDQSDPSLSKPQHITETFN--PDPNWKNFQKPTGSRNSLDESTLGFGYPKFISHEDIRKR-NYVRDNAIFLRASVEI 464
BLAST of TNF receptor-associated factor vs. Ensembl Xenopus
Match: hspb6 (heat shock protein family B (small) member 6 [Source:Xenbase;Acc:XB-GENE-876273]) HSP 1 Score: 113.235 bits (282), Expect = 9.488e-27 Identity = 65/166 (39.16%), Postives = 94/166 (56.63%), Query Frame = 1
Query: 1048 LEM-AANQNQLNY-GEFVWKLDKFTDKMADAKNGINAIIYSESFLTHKNGFKMCLRVDPDGFGDGKGTHLSVFFCLMKGEFDGILEWPFRHSVTFALINQRTRLPHVSRTAKCADYTNNKELIQSTDRNNGFGFDQFLSLKELSSNPD-LMRNNQIFIKCSVDIDS 1536
LEM +A Q +Y G F+WK+ T+K DA G +YS +F T K G+K+CLR+ +G G GKGTH+S+FF +MKGE+D +L WPF+H VTF L++ R A D T+ D N G F + +L+S +R N ++I+C +D +S
Sbjct: 216 LEMRSACLEQTSYDGVFLWKISDLTNKSHDAVTGRAISLYSPAFYTAKYGYKVCLRIYLNGDGAGKGTHVSLFFTVMKGEYDALLPWPFKHKVTFVLVDHNNR--DSVFDAFRPDVTSASFQRPINDMNVASGCPLFCPIAKLNSPKHAYIRENTLYIRCIIDTNS 379
BLAST of TNF receptor-associated factor vs. Ensembl Xenopus
Match: ssh2 (slingshot protein phosphatase 2 [Source:Xenbase;Acc:XB-GENE-993093]) HSP 1 Score: 114.775 bits (286), Expect = 1.521e-26 Identity = 132/548 (24.09%), Postives = 234/548 (42.70%), Query Frame = 1
Query: 148 YNYESVTEIQNDMLCLLCKKLLVNARCAPCSCRFCFTCISDYLDKNE----ICPGN-TED-------CKQELLHL-----NENIYVDQPMNIK--ISKLQVKCK--EMSCDYVD----ELRK-MEEH-SRTCKYRS--------------------VACPYSNIGCDK-CNI---------------------------------SQDKVTDHLQSEIFAHTKLLMDFVVNFNNEMEMLKANNNGLSAVNELLRNEINELKLDGERRREE-------IAELQRKCADQAEEIELLNEDIPALRNVDRNVSDRLDGLQLIIEGNQVAMRAVENDFQQQIAQCATNCQQAEIKQKELIDKIGQMENKQKVDLTEMSNKIDKLSGNVDRKLLEMAANQNQLNYGEFVWKLDKFTDKMADAKNGINAIIYSESFLTHKNGFKMCLRVDPDGFGDGKGTHLSVFFCLMKGEFDGILEWPFRHSVTFALINQRTRLPHVSRTAKCADYTNNKELIQSTDRNNGFGFDQFLSLKELSSNPDLMRNNQIFIKCSVD 1527
Y + ++ C C+ +L N R C RFC TC++ L C N T+D C++E+L L NE + + + + L+ C+ E+SC D +RK + +H +TCKYR V CP I C C++ + ++ H S H L+ ++ ++ ML+ ++ + ++L N++ +++ ER +E+ I +LQR QA++++ L+++I RN+ R D DG++ E Q + +E +A+ A + ++ + I++ QM + + L +M + ++LE A+ G +WK+ + + +A G +YS+ F T G+KMC RV +G G GKGTHLS+FF +M+GE+D +L WPF+ V+ L++Q H+ K D ++ + + N G F++ L N ++++ IFIK VD
Sbjct: 34 YKERFLKPVEEKYKCEKCRLVLCNPRQTECGHRFCETCMNAILSSTSPQCMACEDNITKDKVFKDNCCRREVLALQMFCRNETRGCKELITLGNLLIHLKSDCQFEELSCPRADCKEKVIRKDLSDHIEKTCKYRETPCKFCRNQVPLVEMQKHEDVDCPSVVISCPHMCSVKSLLRSELNAHLLECVNAPSTCSFKRYGCTFKGTNQQIKAHEASSAVQHVNLMKEWSNYLEAKVSMLQNESSEKNKSIQILHNQMCSFEIEIERHKEQLRNNEARIIQLQRVIEGQADKLKDLDKEI---RNL-RQTGDEADGMKSNYESLQNRLSQLE-----VMAKNAASWNPGVLETQ--INRHDQMLSVHDIRLADMDLRF---------QVLETASYN-----GVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVSLMLMDQGPSRRHLGDAFK-PDPNSSSFKKPTGEMNIASGCPVFVAQTVL-ENGTYIKDDTIFIKVIVD 554
BLAST of TNF receptor-associated factor vs. Ensembl Xenopus
Match: slc12a1 (solute carrier family 12 member 1 [Source:Xenbase;Acc:XB-GENE-479925]) HSP 1 Score: 104.76 bits (260), Expect = 2.541e-23 Identity = 123/535 (22.99%), Postives = 233/535 (43.55%), Query Frame = 1
Query: 154 YESVTEIQNDMLCLLCKKLLVNARCAPCSCRFCFTCISDYLDKNEI--CPGNTED-----------CKQELL-----------------------HLNENIY----------VDQPMNIKI-SKLQVKCK-----------EMSCDYVDELRK------MEEHSRTCKYRSVACPYSNIGCDKCNISQDKVTDHLQSEIFAHTKLLMDFVVNFNNEMEMLKANNNGLSAVNELLRNEINELKLDGERRREEIAELQRKCADQAEEI--------ELLNEDIPALRNVDRNVSDRLDGLQLII-EGNQVAMRAVENDFQQQIAQCATNCQQAEIKQKELIDKIGQMENKQKVDLTEMSNKIDKLSGNVDRKLLEMAANQNQLNYGEFVWKLDKFTDKMADAKNGINAIIYSESFLTHKNGFKMCLRVDPDGFGDGKGTHLSVFFCLMKGEFDGILEWPFRHSVTFALINQRTRLPHVSRTAKCADYTNNKELIQSTDRNNGFGFDQFLSLKELSSNPD---LMRNNQIFIKCSVDI 1530
Y V ++Q+ C C +L N C RFC CIS+ ++ +E CP + E+ CK+E+L HL + +Y DQ + ++ L+ +CK MS ++ + +K +++H C + C +SN GC+ + + KV +H + + H M +V+N N ++E LS + L +LK E + +++++ + C + + L+ +D+++ +QL+ E +++ +R + + + + +T + D+I ++ + K +SN +++ N +R L + N G+ +WK+ + K +A G I+S+ F T G+++C R +G G GKG+ LS++F +MKGEFD IL WPF+ VT L++Q + H++ + AD ++ ++ N G +F S +L NP ++++ +FIK VD+
Sbjct: 32 YLFVEQLQDRYKCASCHLVLHNPHQTGCGHRFCEKCISNLIELSETPQCPIDMENIKSHEIFKDNCCKREVLNLLVYCKNSPACDVKVMLGRYQEHLGQCLYEMTLCSNDGCHDQMIRKELKGHLESECKLRQEACIYCKQTMSFNHENNYKKIFFSFQLDKHLCECPEAELQCTFSNYGCN-VMVKRGKVKEHEDTFLRDH----MLYVLNRNMKLE-----EQVLSVLQNL------DLK---EHQIQQLSDTVKWCEKECHQFGQFTGSNGNSLSSTKTLASYIDKSMWLEEQVIQLVSKEHSRLDLRPILDTLESTKQRLST--------LEAYKDRIDNLDGQFKKHDVLLSNHKMQMTSNEERFRLVEGTSYN----GKLIWKITDYERKKREAMEGRAVSIFSQHFYTSWCGYRLCARAYLNGDGSGKGSFLSLYFVVMKGEFDSILLWPFKQKVTLMLLDQSGKKNHITDVFR-ADPNSSSFKRPDSEMNIASGCPRFASHAQL-ENPKNGCYIKDDTLFIKIVVDL 533
BLAST of TNF receptor-associated factor vs. Ensembl Mouse
Match: Traf4 (TNF receptor associated factor 4 [Source:MGI Symbol;Acc:MGI:1202880]) HSP 1 Score: 125.561 bits (314), Expect = 1.108e-30 Identity = 113/501 (22.55%), Postives = 220/501 (43.91%), Query Frame = 1
Query: 139 MRDYNYESVTEIQNDMLCLLCKKLLVNA-RCAPCSCRFCFTCISDYLDKNEICPGNTEDCKQELLHLN-ENIYVDQPMNIKISKLQVKC--KEMSCDYVDELRKMEEHSRTCKYRSVACPYSNIGCDKC--NISQDKVTDHLQSEIFAHTKLLMDFV-VNFNNEM-----------EMLKANNNGLSAVNELLRNEINELKLDGERRREEIAELQRKCAD---QAEEIELLNEDIPALRNVDRNVSDRLDGLQLIIEGNQVAMRAVENDFQQQIAQCATNC------QQAEIKQKELIDKIGQMENKQKVDLTEMSNKIDKLSGNVDRKLLEMAANQNQLNYGEFVWKLDKFTDKMADAKNGINAIIYSESFLTHKNGFKMCLRVDPDGFGDGKGTHLSVFFCLMKGEFDGILEWPFRHSVTFALINQR----TRLPHVSRT----AKCADYTNNKELIQSTDRNN-GFGFDQFLSLKELSSNPDLMRNNQIFIKCSVDID 1533
M ++Y+ + + + +LC LC K + + + C RFC TC+ ++L + C ++ L L+ IY D + +++ L ++C E C + LR ++ H TC + V CP ++C +S+ + HLQ + +L +F +F+ E + N G + LL + +R + A ++ Q+ + + +P R D + + A V F++ + C C + E K + + + ++Q+ +L E+ ++++LS D G +WK+ + ++ +AK N +S +F THK G+K+ + +G G G+GTHLS++ ++ G FD +LEWPF VTF+L++Q + HV+ T ++ S D ++ GFG+ +F+S +++ + +R++ +FI+ SV++
Sbjct: 1 MPGFDYKFLEKPKRRLLCPLCGKPMREPVQVSTCGHRFCDTCLQEFLSEGVF------KCPEDQLPLDYAKIYPDPELEVQVLGLAIRCIHSEEGCRWSGPLRHLQGHLNTCSFNVVPCP------NRCPAKLSRRDLPAHLQHDC-PKRRLKCEFCGCDFSGEAYESHEGVCPQESVYCENKCGARMMRRLLAQHATS---ECPKRTQPCAYCTKEFVYDTIQSHQYQCPRLPVPCPNQCGVGTVAREDLPTHLKDSCSTAF--VLCPFKE--SGCKHRCPKLAMGRHVEESVKPHLAMMCALVSRQRQELQELRRELEELSIGSD---------------GVLIWKIGSYGRRLQEAKAKPNLECFSPAFYTHKYGYKLQVSAFLNGNGSGEGTHLSIYIRVLPGAFDNLLEWPFARRVTFSLLDQSDPGLAKPQHVTETFHPDPNWKNFQKPGTWRGSLDESSLGFGYPKFISHQDIRKR-NYVRDDAVFIRASVELP 465
BLAST of TNF receptor-associated factor vs. Ensembl Mouse
Match: Traf2 (TNF receptor-associated factor 2 [Source:MGI Symbol;Acc:MGI:101835]) HSP 1 Score: 123.25 bits (308), Expect = 1.150e-29 Identity = 124/501 (24.75%), Postives = 201/501 (40.12%), Query Frame = 1
Query: 166 TEIQNDMLCLLCKKLLVNARCAPCSCRFCFTCISDYLDKNEICPGNTEDCKQELLHL-------NENIYVDQPMNIKISKLQVKCKEMSCDYVDELRKMEE-HSRTCKYRSVACPY--------------------SNIGCDKCNISQDKVTDHLQSEIFAHTKLLMDFVVNFNNEMEMLKANNNGLSAVNELLR------NEINELK----LDGERRREEIAELQRKCADQAEEIELLNEDIPALRNVDRNVSDRLDGLQLIIEGNQVAMRAVENDFQQQIAQCATNC-QQAEIKQKELIDKIGQMENKQKVDLTEMSNKIDKLSGNVDRKLLEMAANQNQLNY-------GEFVWKLDKFTDKMADAKNGINAIIYSESFLTHKNGFKMCLRVDPDGFGDGKGTHLSVFFCLMKGEFDGILEWPFRHSVTFALINQRTRLPHVSRTAKCADYTNNKELIQSTDRNNGFGFDQFLSLKELSSNPDLMRNNQIFIKCSVDI 1530
T ++ LC CK +L A C R+C C++ L P N C E L+ + + + D ++ L C C + L++ E H C + CP ++ C C V + E+ L D E + + S L R +E+ E + + +R RE +A L + LN+ P L + + ++ + I+ V N +++A A C +Q + Q DKI +SNK+ +L ++ K L MA + +++ G F+WK+ FT K +A G I+S +F T + G+KMCLRV +G G G+GTHLS+FF +MKG D +L+WPF VT L++ R HV + D T++ +D N G F + ++ + +R++ IFIK VD+
Sbjct: 26 TRLEAKYLCSACKNILRRPFQAQCGHRYCSFCLTSILSSG---PQNCAACVYEGLYEEGISILESSSAFPDNAARREVESLPAVCPNDGCTWKGTLKEYESCHEGLCPFLLTECPACKGLVRLSEKEHHTEQECPKRSLSCQHCRAPCSHVDLEVHYEVCPKFPLTCDGCGKKKIPRETFQDHVRACSKCRVLCRFHTVGCSEMVETENLQDHELQRLREHLALLLSSFLEAQASPGTLNQVGPELLQRCQILEQKIATFENIV--------CVLNREVERVAVTAEACSRQHRLDQ----DKI-----------EALSNKVQQLERSIGLKDLAMADLEQKVSELEVSTYDGVFIWKISDFTRKRQEAVAGRTPAIFSPAFYTSRYGYKMCLRVYLNGDGTGRGTHLSLFFVVMKGPNDALLQWPFNQKVTLMLLDHNNR-EHVIDAFR-PDVTSSSFQRPVSDMNIASGCPLFCPVSKMEAKNSYVRDDAIFIKAIVDL 498
BLAST of TNF receptor-associated factor vs. Ensembl Mouse
Match: Traf2 (TNF receptor-associated factor 2 [Source:MGI Symbol;Acc:MGI:101835]) HSP 1 Score: 121.324 bits (303), Expect = 5.502e-29 Identity = 125/505 (24.75%), Postives = 202/505 (40.00%), Query Frame = 1
Query: 166 TEIQNDMLCLLCKKLLVNARCAPCSCRFCFTCISDYLDKNEIC----PGNTEDCKQELLHL-------NENIYVDQPMNIKISKLQVKCKEMSCDYVDELRKMEE-HSRTCKYRSVACPY--------------------SNIGCDKCNISQDKVTDHLQSEIFAHTKLLMDFVVNFNNEMEMLKANNNGLSAVNELLR------NEINELK----LDGERRREEIAELQRKCADQAEEIELLNEDIPALRNVDRNVSDRLDGLQLIIEGNQVAMRAVENDFQQQIAQCATNC-QQAEIKQKELIDKIGQMENKQKVDLTEMSNKIDKLSGNVDRKLLEMAANQNQLNY-------GEFVWKLDKFTDKMADAKNGINAIIYSESFLTHKNGFKMCLRVDPDGFGDGKGTHLSVFFCLMKGEFDGILEWPFRHSVTFALINQRTRLPHVSRTAKCADYTNNKELIQSTDRNNGFGFDQFLSLKELSSNPDLMRNNQIFIKCSVDI 1530
T ++ LC CK +L A C R+C C++ L I P N C E L+ + + + D ++ L C C + L++ E H C + CP ++ C C V + E+ L D E + + S L R +E+ E + + +R RE +A L + LN+ P L + + ++ + I+ V N +++A A C +Q + Q DKI +SNK+ +L ++ K L MA + +++ G F+WK+ FT K +A G I+S +F T + G+KMCLRV +G G G+GTHLS+FF +MKG D +L+WPF VT L++ R HV + D T++ +D N G F + ++ + +R++ IFIK VD+
Sbjct: 26 TRLEAKYLCSACKNILRRPFQAQCGHRYCSFCLTSILRCASILSSSGPQNCAACVYEGLYEEGISILESSSAFPDNAARREVESLPAVCPNDGCTWKGTLKEYESCHEGLCPFLLTECPACKGLVRLSEKEHHTEQECPKRSLSCQHCRAPCSHVDLEVHYEVCPKFPLTCDGCGKKKIPRETFQDHVRACSKCRVLCRFHTVGCSEMVETENLQDHELQRLREHLALLLSSFLEAQASPGTLNQVGPELLQRCQILEQKIATFENIV--------CVLNREVERVAVTAEACSRQHRLDQ----DKI-----------EALSNKVQQLERSIGLKDLAMADLEQKVSELEVSTYDGVFIWKISDFTRKRQEAVAGRTPAIFSPAFYTSRYGYKMCLRVYLNGDGTGRGTHLSLFFVVMKGPNDALLQWPFNQKVTLMLLDHNNR-EHVIDAFR-PDVTSSSFQRPVSDMNIASGCPLFCPVSKMEAKNSYVRDDAIFIKAIVDL 505
BLAST of TNF receptor-associated factor vs. Ensembl Mouse
Match: Traf3 (TNF receptor-associated factor 3 [Source:MGI Symbol;Acc:MGI:108041]) HSP 1 Score: 120.168 bits (300), Expect = 1.661e-28 Identity = 128/523 (24.47%), Postives = 228/523 (43.59%), Query Frame = 1
Query: 148 YNYESVTEIQNDMLCLLCKKLLVNARCAPCSCRFCFTCISDYLDKNEI-CPGNTED-----------CKQELLHL-----NENIYVDQPMNIK--ISKLQVKCK--EMSCDYVD----ELRK-MEEH-SRTCKYRSVAC--------------------PYSNIGCD-KCNI--------SQDKVTDHLQSEIFAHTKLLMDFVVNFNNEMEMLKANNNGLSAVNELLRNEINELKLDGERRRE-------EIAELQRKCADQAEEIELLNEDIPALRNVDRNVSDRLDGLQLIIEGNQVAMRAVENDFQQQIAQCATNCQQAEIKQKELIDKIGQMENKQKVDLTEMSNKIDKLSGNVDRKLLEMAANQNQLNYGEFVWKLDKFTDKMADAKNGINAIIYSESFLTHKNGFKMCLRVDPDGFGDGKGTHLSVFFCLMKGEFDGILEWPFRHSVTFALINQRTRLPHVSRTAKCADYTNNKELIQSTDRNNGFGFDQFLSLKELSSNPDLMRNNQIFIKCSVD 1527
Y + V +++ C C+ +L N + C RFC +C++ L + C E CK+E+L L NE + + + + L+ +C+ E+ C D LRK + +H + CKYR C P + C KC++ + ++ H S H LL ++ + ++ +L+ + + + L N+I +++ ER++E +I LQR QAE+++ L+++I R + D ++ +E Q + +E+ + Q A N E + + + QM + + L +M + ++LE A+ G +WK+ + + +A G +YS+ F T G+KMC RV +G G GKGTHLS+FF +M+GE+D +L WPF+ VT L++Q + H+ K D ++ + + N G F++ L N ++++ IFIK VD
Sbjct: 38 YKEKFVKTVEDKYKCEKCRLVLCNPKQTECGHRFCESCMAALLSSSSPKCTACQESIIKDKVFKDNCCKREILALQVYCRNEGRGCAEQLTLGHLLVHLKNECQFEELPCLRADCKEKVLRKDLRDHVEKACKYREATCSHCKSQVPMIKLQKHEDTDCPCVVVSCPHKCSVQTLLRSEGTNQQIKAHEASSAVQHVNLLKEWSNSLEKKVSLLQNESVEKNKSIQSLHNQICSFEIEIERQKEMLRNNESKILHLQRVIDSQAEKLKELDKEIRPFRQN----WEEADSMKSSVESLQNRVTELES-VDKSAGQAARNTGLLESQ----LSRHDQMLSVHDIRLADMDLRF---------QVLETASYN-----GVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLMLMDQGSSRRHLGDAFK-PDPNSSSFKKPTGEMNIASGCPVFVAQTVL-ENGTYIKDDTIFIKVIVD 535
BLAST of TNF receptor-associated factor vs. Ensembl Mouse
Match: Traf3 (TNF receptor-associated factor 3 [Source:MGI Symbol;Acc:MGI:108041]) HSP 1 Score: 120.168 bits (300), Expect = 1.661e-28 Identity = 128/523 (24.47%), Postives = 228/523 (43.59%), Query Frame = 1
Query: 148 YNYESVTEIQNDMLCLLCKKLLVNARCAPCSCRFCFTCISDYLDKNEI-CPGNTED-----------CKQELLHL-----NENIYVDQPMNIK--ISKLQVKCK--EMSCDYVD----ELRK-MEEH-SRTCKYRSVAC--------------------PYSNIGCD-KCNI--------SQDKVTDHLQSEIFAHTKLLMDFVVNFNNEMEMLKANNNGLSAVNELLRNEINELKLDGERRRE-------EIAELQRKCADQAEEIELLNEDIPALRNVDRNVSDRLDGLQLIIEGNQVAMRAVENDFQQQIAQCATNCQQAEIKQKELIDKIGQMENKQKVDLTEMSNKIDKLSGNVDRKLLEMAANQNQLNYGEFVWKLDKFTDKMADAKNGINAIIYSESFLTHKNGFKMCLRVDPDGFGDGKGTHLSVFFCLMKGEFDGILEWPFRHSVTFALINQRTRLPHVSRTAKCADYTNNKELIQSTDRNNGFGFDQFLSLKELSSNPDLMRNNQIFIKCSVD 1527
Y + V +++ C C+ +L N + C RFC +C++ L + C E CK+E+L L NE + + + + L+ +C+ E+ C D LRK + +H + CKYR C P + C KC++ + ++ H S H LL ++ + ++ +L+ + + + L N+I +++ ER++E +I LQR QAE+++ L+++I R + D ++ +E Q + +E+ + Q A N E + + + QM + + L +M + ++LE A+ G +WK+ + + +A G +YS+ F T G+KMC RV +G G GKGTHLS+FF +M+GE+D +L WPF+ VT L++Q + H+ K D ++ + + N G F++ L N ++++ IFIK VD
Sbjct: 38 YKEKFVKTVEDKYKCEKCRLVLCNPKQTECGHRFCESCMAALLSSSSPKCTACQESIIKDKVFKDNCCKREILALQVYCRNEGRGCAEQLTLGHLLVHLKNECQFEELPCLRADCKEKVLRKDLRDHVEKACKYREATCSHCKSQVPMIKLQKHEDTDCPCVVVSCPHKCSVQTLLRSEGTNQQIKAHEASSAVQHVNLLKEWSNSLEKKVSLLQNESVEKNKSIQSLHNQICSFEIEIERQKEMLRNNESKILHLQRVIDSQAEKLKELDKEIRPFRQN----WEEADSMKSSVESLQNRVTELES-VDKSAGQAARNTGLLESQ----LSRHDQMLSVHDIRLADMDLRF---------QVLETASYN-----GVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLMLMDQGSSRRHLGDAFK-PDPNSSSFKKPTGEMNIASGCPVFVAQTVL-ENGTYIKDDTIFIKVIVD 535
BLAST of TNF receptor-associated factor vs. UniProt/SwissProt
Match: sp|Q61382|TRAF4_MOUSE (TNF receptor-associated factor 4 OS=Mus musculus OX=10090 GN=Traf4 PE=1 SV=2) HSP 1 Score: 125.561 bits (314), Expect = 7.748e-30 Identity = 113/501 (22.55%), Postives = 220/501 (43.91%), Query Frame = 1
Query: 139 MRDYNYESVTEIQNDMLCLLCKKLLVNA-RCAPCSCRFCFTCISDYLDKNEICPGNTEDCKQELLHLN-ENIYVDQPMNIKISKLQVKC--KEMSCDYVDELRKMEEHSRTCKYRSVACPYSNIGCDKC--NISQDKVTDHLQSEIFAHTKLLMDFV-VNFNNEM-----------EMLKANNNGLSAVNELLRNEINELKLDGERRREEIAELQRKCAD---QAEEIELLNEDIPALRNVDRNVSDRLDGLQLIIEGNQVAMRAVENDFQQQIAQCATNC------QQAEIKQKELIDKIGQMENKQKVDLTEMSNKIDKLSGNVDRKLLEMAANQNQLNYGEFVWKLDKFTDKMADAKNGINAIIYSESFLTHKNGFKMCLRVDPDGFGDGKGTHLSVFFCLMKGEFDGILEWPFRHSVTFALINQR----TRLPHVSRT----AKCADYTNNKELIQSTDRNN-GFGFDQFLSLKELSSNPDLMRNNQIFIKCSVDID 1533
M ++Y+ + + + +LC LC K + + + C RFC TC+ ++L + C ++ L L+ IY D + +++ L ++C E C + LR ++ H TC + V CP ++C +S+ + HLQ + +L +F +F+ E + N G + LL + +R + A ++ Q+ + + +P R D + + A V F++ + C C + E K + + + ++Q+ +L E+ ++++LS D G +WK+ + ++ +AK N +S +F THK G+K+ + +G G G+GTHLS++ ++ G FD +LEWPF VTF+L++Q + HV+ T ++ S D ++ GFG+ +F+S +++ + +R++ +FI+ SV++
Sbjct: 1 MPGFDYKFLEKPKRRLLCPLCGKPMREPVQVSTCGHRFCDTCLQEFLSEGVF------KCPEDQLPLDYAKIYPDPELEVQVLGLAIRCIHSEEGCRWSGPLRHLQGHLNTCSFNVVPCP------NRCPAKLSRRDLPAHLQHDC-PKRRLKCEFCGCDFSGEAYESHEGVCPQESVYCENKCGARMMRRLLAQHATS---ECPKRTQPCAYCTKEFVYDTIQSHQYQCPRLPVPCPNQCGVGTVAREDLPTHLKDSCSTAF--VLCPFKE--SGCKHRCPKLAMGRHVEESVKPHLAMMCALVSRQRQELQELRRELEELSIGSD---------------GVLIWKIGSYGRRLQEAKAKPNLECFSPAFYTHKYGYKLQVSAFLNGNGSGEGTHLSIYIRVLPGAFDNLLEWPFARRVTFSLLDQSDPGLAKPQHVTETFHPDPNWKNFQKPGTWRGSLDESSLGFGYPKFISHQDIRKR-NYVRDDAVFIRASVELP 465
BLAST of TNF receptor-associated factor vs. UniProt/SwissProt
Match: sp|P39429|TRAF2_MOUSE (TNF receptor-associated factor 2 OS=Mus musculus OX=10090 GN=Traf2 PE=1 SV=1) HSP 1 Score: 123.25 bits (308), Expect = 8.041e-29 Identity = 124/501 (24.75%), Postives = 201/501 (40.12%), Query Frame = 1
Query: 166 TEIQNDMLCLLCKKLLVNARCAPCSCRFCFTCISDYLDKNEICPGNTEDCKQELLHL-------NENIYVDQPMNIKISKLQVKCKEMSCDYVDELRKMEE-HSRTCKYRSVACPY--------------------SNIGCDKCNISQDKVTDHLQSEIFAHTKLLMDFVVNFNNEMEMLKANNNGLSAVNELLR------NEINELK----LDGERRREEIAELQRKCADQAEEIELLNEDIPALRNVDRNVSDRLDGLQLIIEGNQVAMRAVENDFQQQIAQCATNC-QQAEIKQKELIDKIGQMENKQKVDLTEMSNKIDKLSGNVDRKLLEMAANQNQLNY-------GEFVWKLDKFTDKMADAKNGINAIIYSESFLTHKNGFKMCLRVDPDGFGDGKGTHLSVFFCLMKGEFDGILEWPFRHSVTFALINQRTRLPHVSRTAKCADYTNNKELIQSTDRNNGFGFDQFLSLKELSSNPDLMRNNQIFIKCSVDI 1530
T ++ LC CK +L A C R+C C++ L P N C E L+ + + + D ++ L C C + L++ E H C + CP ++ C C V + E+ L D E + + S L R +E+ E + + +R RE +A L + LN+ P L + + ++ + I+ V N +++A A C +Q + Q DKI +SNK+ +L ++ K L MA + +++ G F+WK+ FT K +A G I+S +F T + G+KMCLRV +G G G+GTHLS+FF +MKG D +L+WPF VT L++ R HV + D T++ +D N G F + ++ + +R++ IFIK VD+
Sbjct: 26 TRLEAKYLCSACKNILRRPFQAQCGHRYCSFCLTSILSSG---PQNCAACVYEGLYEEGISILESSSAFPDNAARREVESLPAVCPNDGCTWKGTLKEYESCHEGLCPFLLTECPACKGLVRLSEKEHHTEQECPKRSLSCQHCRAPCSHVDLEVHYEVCPKFPLTCDGCGKKKIPRETFQDHVRACSKCRVLCRFHTVGCSEMVETENLQDHELQRLREHLALLLSSFLEAQASPGTLNQVGPELLQRCQILEQKIATFENIV--------CVLNREVERVAVTAEACSRQHRLDQ----DKI-----------EALSNKVQQLERSIGLKDLAMADLEQKVSELEVSTYDGVFIWKISDFTRKRQEAVAGRTPAIFSPAFYTSRYGYKMCLRVYLNGDGTGRGTHLSLFFVVMKGPNDALLQWPFNQKVTLMLLDHNNR-EHVIDAFR-PDVTSSSFQRPVSDMNIASGCPLFCPVSKMEAKNSYVRDDAIFIKAIVDL 498
BLAST of TNF receptor-associated factor vs. UniProt/SwissProt
Match: sp|Q9BUZ4|TRAF4_HUMAN (TNF receptor-associated factor 4 OS=Homo sapiens OX=9606 GN=TRAF4 PE=1 SV=1) HSP 1 Score: 122.094 bits (305), Expect = 1.321e-28 Identity = 110/508 (21.65%), Postives = 218/508 (42.91%), Query Frame = 1
Query: 139 MRDYNYESVTEIQNDMLCLLCKKLLVNA-RCAPCSCRFCFTCISDYLDKNEICPGNTEDCKQELLHLN-ENIYVDQPMNIKISKLQVKC--KEMSCDYVDELRKMEEHSRTCKYRSVACPYSNIGCDKC--NISQDKVTDHLQSEIFAHTKLLMDFV-VNFNNEM-----------EMLKANNNGLSAVNELLRNEIN---------------ELKLDG-ERRREEIAELQRKCADQAEEIELLNEDIPALRNVDRNVSDRLDGLQLIIEGNQVAMRAVENDFQQQIAQCATNCQQAEIKQKELIDKIGQMENKQKVDLTEMSNKIDKLSGNVDRKLLEMAANQNQLNYGEFVWKLDKFTDKMADAKNGINAIIYSESFLTHKNGFKMCLRVDPDGFGDGKGTHLSVFFCLMKGEFDGILEWPFRHSVTFALINQR----TRLPHVSRT----AKCADYTNNKELIQSTDRNN-GFGFDQFLSLKELSSNPDLMRNNQIFIKCSVDID 1533
M ++Y+ + + + +LC LC K + + + C RFC TC+ ++L + C ++ L L+ IY D + +++ L ++C E C + LR ++ H TC + + CP ++C +S+ + HLQ + +L +F +F+ E + N G + LL E D + + + L C +Q + ED+P N + L + ++ A+ ++ + K + + + ++Q+ +L E+ ++++LS D G +WK+ + ++ +AK N +S +F THK G+K+ + +G G G+GTHLS++ ++ G FD +LEWPF VTF+L++Q + HV+ T ++ S D ++ GFG+ +F+S +++ + +R++ +FI+ +V++
Sbjct: 1 MPGFDYKFLEKPKRRLLCPLCGKPMREPVQVSTCGHRFCDTCLQEFLSEGVF------KCPEDQLPLDYAKIYPDPELEVQVLGLPIRCIHSEEGCRWSGPLRHLQGHLNTCSFNVIPCP------NRCPMKLSRRDLPAHLQHDC-PKRRLKCEFCGCDFSGEAYESHEGMCPQESVYCENKCGARMMRRLLAQHATSECPKRTQPCTYCTKEFVFDTIQSHQYQCPRLPVACPNQCGVGTVAREDLPGHLKDSCNTALVLCPFKDSGCKHRCPKLAMARHVEESV--------------KPHLAMMCALVSRQRQELQELRRELEELSVGSD---------------GVLIWKIGSYGRRLQEAKAKPNLECFSPAFYTHKYGYKLQVSAFLNGNGSGEGTHLSLYIRVLPGAFDNLLEWPFARRVTFSLLDQSDPGLAKPQHVTETFHPDPNWKNFQKPGTWRGSLDESSLGFGYPKFISHQDIRKR-NYVRDDAVFIRAAVELP 465
BLAST of TNF receptor-associated factor vs. UniProt/SwissProt
Match: sp|P70191|TRAF5_MOUSE (TNF receptor-associated factor 5 OS=Mus musculus OX=10090 GN=Traf5 PE=1 SV=1) HSP 1 Score: 116.701 bits (291), Expect = 1.732e-26 Identity = 127/538 (23.61%), Postives = 228/538 (42.38%), Query Frame = 1
Query: 145 DYNYESVTEIQNDMLCLLCKKLLVNARCAPCSCRFCFTCISDYLDKNE--ICPGNTED-----------CKQELLHLNENIYV-DQP---MNIKISKLQ----------VKCKEMSCDYVDELRKMEEH-SRTCKYRSV--------------------ACPYSNIGC-DKC--NISQDKVTDHL-------QSEIFAHTKLLMDFVVNFNNEMEMLKANNNGLSAV--NELLRNEINELKLDGERRREEIAELQRKCADQAEEIELLNEDIPALRNVDRNVSDRLDGLQLIIEGNQVAMRAVENDFQQQIAQCATNCQQAEIKQKELIDKIGQMENKQKVDLTEMSN-KIDKLSGNVDRKLLEMAANQNQLN--------------YGEFVWKLDKFTDKMADAKNGINAIIYSESFLTHKNGFKMCLRVDPDGFGDGKGTHLSVFFCLMKGEFDGILEWPFRHSVTFALINQRTRLPHVSRTAKCADYTNNKELIQSTDRNNGFGFDQFLSLKEL-SSNPDLMRNNQIFIKCSVDI 1530
D Y+ V +++ C C +L N C RFC CI + N ICP + E CK+E+L+L+ +Y + P I + + Q V C SC + ++EH S C++R +CP + C ++C I + +V +HL Q F H + E E ++ L + N L I++L E++ +I +L AE ++ +++ + L +Q + + +E +Q + N Q + + + L+D + + KQ++ E S+ ++ L G + + ++ QLN G+ +WK+ + K +A G ++S+ F T + G+++C R +G G GKGTHLS++F +M+GEFD +L+WPFR VT L++Q + H+ T K AD ++ + N G +F+S L +S ++++ +F+K +VD+
Sbjct: 30 DTEYQFVEQLEERYKCAFCHSVLHNPHQTGCGHRFCQQCIRSLRELNSVPICPVDKEVIKPQEVFKDNCCKREVLNLH--VYCKNAPGCNARIILGRFQDHLQHCSFQAVPCPNESCREAMLRKDVKEHLSAYCRFREEKCLYCKRDIVVTNLQDHEENSCPAYPVSCPNRCVQTIPRARVNEHLTVCPEAEQDCPFKHYGCTVKGKRGNLLEHERAALQDHMLLVLEKNYQLEQRISDLYQSLEQKESKIQQL-------AETVKKFEKELKQFTQMFGRNGTFLSNVQALTSHTDKSA-WLEAQVRQLLQ--IVNQQPSRLDLRSLVDAVDSV--KQRITQLEASDQRLVLLEGETSKHDAHINIHKAQLNKNEERFKQLEGACYSGKLIWKVTDYRVKKREAVEGHTVSVFSQPFYTSRCGYRLCARAYLNGDGSGKGTHLSLYFVVMRGEFDSLLQWPFRQRVTLMLLDQSGKKNHIVETFK-ADPNSSSFKRPDGEMNIASGCPRFVSHSTLENSKNTYIKDDTLFLKVAVDL 552
BLAST of TNF receptor-associated factor vs. UniProt/SwissProt
Match: sp|Q60803|TRAF3_MOUSE (TNF receptor-associated factor 3 OS=Mus musculus OX=10090 GN=Traf3 PE=1 SV=2) HSP 1 Score: 113.235 bits (282), Expect = 2.768e-25 Identity = 95/371 (25.61%), Postives = 171/371 (46.09%), Query Frame = 1
Query: 436 KMEEHSRTCKYRSVACPYSNIGCDKCNISQDKVTDHLQSEIFAHTKLLMDFVVNFNNEMEMLKANNNGLSAVNELLRNEINELKLDGERRRE-------EIAELQRKCADQAEEIELLNEDIPALRNVDRNVSDRLDGLQLIIEGNQVAMRAVENDFQQQIAQCATNCQQAEIKQKELIDKIGQMENKQKVDLTEMSNKIDKLSGNVDRKLLEMAANQNQLNYGEFVWKLDKFTDKMADAKNGINAIIYSESFLTHKNGFKMCLRVDPDGFGDGKGTHLSVFFCLMKGEFDGILEWPFRHSVTFALINQRTRLPHVSRTAKCADYTNNKELIQSTDRNNGFGFDQFLSLKELSSNPDLMRNNQIFIKCSVD 1527
++ H C C + GC +Q ++ H S H LL ++ + ++ +L+ + + + L N+I +++ ER++E +I LQR QAE+++ L+++I R + D ++ +E Q + +E+ + Q A N E + + + QM + + L +M + ++LE A+ G +WK+ + + +A G +YS+ F T G+KMC RV +G G GKGTHLS+FF +M+GE+D +L WPF+ VT L++Q + H+ K D ++ + + N G F++ L N ++++ IFIK VD
Sbjct: 216 ELSAHLSECVNAPSTCSFKRYGCVFQGTNQ-QIKAHEASSAVQHVNLLKEWSNSLEKKVSLLQNESVEKNKSIQSLHNQICSFEIEIERQKEMLRNNESKILHLQRVIDSQAEKLKELDKEIRPFRQN----WEEADSMKSSVESLQNRVTELES-VDKSAGQAARNTGLLESQ----LSRHDQMLSVHDIRLADMDLRF---------QVLETASYN-----GVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLMLMDQGSSRRHLGDAFK-PDPNSSSFKKPTGEMNIASGCPVFVAQTVL-ENGTYIKDDTIFIKVIVD 560
BLAST of TNF receptor-associated factor vs. TrEMBL
Match: A0A0F7GWW3 (TNF receptor associated factor 4 (Fragment) OS=Schmidtea mediterranea OX=79327 PE=2 SV=1) HSP 1 Score: 310.457 bits (794), Expect = 1.170e-100 Identity = 153/166 (92.17%), Postives = 159/166 (95.78%), Query Frame = 1
Query: 334 LNENIYVDQPMNIKISKLQVKCKEMSCDYVDELRKMEEHSRTCKYRSVACPYSNIGCDKCNISQDKVTDHLQSEIFAHTKLLMDFVVNFNNEMEMLKANNNGLSAVNELLRNEINELKLDGERRREEIAELQRKCADQAEEIELLNEDIPALRNVDRNVSDRLDGL 831
LNENI VD PMN+KI+KLQVKCKE SCDYVDELRKME+HSRTCKYRSVACPYSNIGCDKCNISQDKVTDHLQSEIF HTKLLMDFVVNFNNEMEMLKANNNGLS VNELLRNEINELKLDG+RRR EI +LQRKCA+QAEEIELLNEDIPALRNVDRNVSDRLDGL
Sbjct: 12 LNENICVDYPMNMKIAKLQVKCKEKSCDYVDELRKMEDHSRTCKYRSVACPYSNIGCDKCNISQDKVTDHLQSEIFVHTKLLMDFVVNFNNEMEMLKANNNGLSPVNELLRNEINELKLDGDRRRVEIGDLQRKCANQAEEIELLNEDIPALRNVDRNVSDRLDGL 177
BLAST of TNF receptor-associated factor vs. TrEMBL
Match: T1E101 (TRAF-6 OS=Dendrocoelum lacteum OX=27895 PE=2 SV=1) HSP 1 Score: 183.726 bits (465), Expect = 2.084e-48 Identity = 135/489 (27.61%), Postives = 245/489 (50.10%), Query Frame = 1
Query: 103 MSGSKLENVGQIMRDYNYESVTE-IQNDMLCLLCKKLLVNARCAPCSCRFCFTCISDYLDKNE-ICPGNTEDCKQELLHLNENIYVDQPMNIKISKLQVKCKEMSCDYVDELRKMEEHSRTCKYRSVACPYSNIGCDKCNISQDKVTDHLQSEIFAHTKLLMDFVVNFNNEMEMLKANNNGLSAVNELLRNEINELKLDGERRREEIAELQRKCADQ-AEEIELLNEDIPALRNVDRNVSDRLDGLQLIIEGNQVAMRAVENDFQQQIAQCATNCQQAEIKQKELIDKIGQMENKQKVDLTEMSNKIDKLSGNVDRKLLEMAANQNQLNY---------GEFVWKLDKFTDKMADAKNGINAIIYSESFLTHKNGFKMCLRVDPDGFGDGKGTHLSVFFCLMKGEFDGILEWPFRHSVTFALINQRTRLPHVSRTAKCADYTNNKELI-QSTDRNNGF--GFDQFLSLKELSSNPDLMRNNQIFIKCSV 1524
M SKL+NV +++ YN + V E + ND+LC+LC KL+ +A + C C +C+TCI YL +N CPG+ +CK++ L+L +++ + ++ +IS++ VKC + C+Y EL +++EH C SV CP IGC++ + +D++ HL ++ HT+L+M F +E+ N+N NE + +I+ LK E+ +Q+ D+ ++E L I LRN D + +Q + + + E++ ++ + Q+ E + +L + +G + K +V ++ +I + N+D E N L +F+W++++++ K + +YS+SF +H +K CL + +GD G ++ +MKGE D LEWP R +VT ++I Q + H + + Y NK+ + D N + G D + + P ++ N+ I + C V
Sbjct: 1 MIPSKLDNVQELLSKYNVKRVDESVNNDLLCILCNKLMRDACESACGCHYCYTCIRIYLSQNHNYCPGDKTECKEDYLNLEGDVFRNIRLSTRISRIVVKCPNIRCNYTSELLRLKEHLDKCTPESVECPCVTIGCEEEPLLKDEMAKHLTDQVLRHTQLIMSFCNELKSEI-----NHN-----NETTKEDISHLK--------EVLRVQKALNDEKTAQMEFL---IEELRNKDNMILVLSQDIQEVKNEMITLLTSKESELKKLKSDIQIFRQEIEFMKNDL-EVVGSTDIKNQV--KDLKKEIFGIKMNIDSNNEERERKMNNLIRLNKLCPNVDMDFMWRIEEYSKKRRTVTD-----VYSDSFQSH--NYKFCLNLYI--YGDNLG----LWCVIMKGEKDDFLEWPMRRTVTLSIIEQDSLKTHKTTVFQYDTYQRNKKAFDRPKDERNDYCIGTDSLVRYSYIKETPMILVNDSIIVACVV 452
BLAST of TNF receptor-associated factor vs. TrEMBL
Match: A0A5A9NXF1 (TNF receptor-associated factor OS=Triplophysa tibetana OX=1572043 GN=E1301_Tti007446 PE=3 SV=1) HSP 1 Score: 150.599 bits (379), Expect = 6.881e-36 Identity = 136/504 (26.98%), Postives = 221/504 (43.85%), Query Frame = 1
Query: 184 MLCLLCKKLLVNARCAPCSCRFCFTCISDYLDKNE--ICPGNTEDCKQE----LLHLNENIYVDQPMNIKISKLQVKCKEMSCDYVDELRKMEEHSRTCKYRSV---------------------ACPYSNIGCDKCNI---------SQDKVTDHLQSEIFAHTKLLMDFVVNFNNEM--------EMLKANNNGLSAVNELLRNEINELKLDGERR--REEIAELQRKCADQA--EEIELLNEDIPALRNVDRNVSDRLDGLQLIIEGNQVAMRAVENDF--QQQIAQCATNCQQAEIKQKELIDKIGQMENKQKVDLTEMSNKIDKLSGNVDRKLLEMAANQNQLNYGEFVWKLDKFTDKMADAKNGINAIIYSESFLTHKNGFKMCLRVDPDGFGDGKGTHLSVFFCLMKGEFDGILEWPFRHSVTFALI--NQRTRLPHVSRTAKCADYTNNKELIQSTDRNNGFGFDQFLSLKELSSNPDLM-RNNQIFIKCSVDIDS 1536
LC C +L AR C R+C C++ L N+ +C ED E +L L++ + D +N +I L+V C C + L+ E+H C+Y + CP + C C+ + DKV +H H +LL++ + + + E+L G + + L+ +E +EL+ DG ++ + L A+ A ++++ L + + + N+ + L +E Q+ + A+E D QQI Q Q E K +E + + ++ + +T + I L QN G F+W+L T + +A G YS +F T + GFK+C+R+ +G G GKGTH+S+FF +MKGE+DGIL+WPFRH VTF LI NQR + R C+ + ++ N G F L +L S +++ I+IKC VD S
Sbjct: 38 FLCSNCNNVLNKARQTVCGHRYCLACVNWLLRNNKDLVCTKCKEDQSIESDTSVLTLDQ-FFNDAAINKEILDLKVHCANQGCPWRSTLKNFEDHQSQCEYALIPCNIGCGIMVQRKALATHLERGCPNNKTTCASCSGVLTPRELQGNADKVKEHESCSHVGHLQLLLEVIRGLQSNLSSQERGIPEILDFLQPGTTG-SSLVSHEESELETDGGESGVNDKASSLHDDQAELAVGQQLDTLQQRVQVMENI-------ISALNREVEKTQIGVVALERDNLNNQQIIQ------QLETKVEEQQEWL----TRKDIHITSLQQCISGL--------------QNVSYDGTFLWRLCDVTQSLREAATGHKISQYSPAFYTARYGFKVCMRLYLNGDGVGKGTHISLFFVIMKGEYDGILQWPFRHKVTFFLIDQNQREHVIDAFRPDLCSASFHQP----VSEMNVASGCPLFFPLGKLRSPKHAYCKDDTIYIKCVVDTSS 504
BLAST of TNF receptor-associated factor vs. TrEMBL
Match: A0A226P8K3 (TNF receptor-associated factor OS=Colinus virginianus OX=9014 GN=H355_006777 PE=3 SV=1) HSP 1 Score: 144.821 bits (364), Expect = 8.402e-34 Identity = 139/508 (27.36%), Postives = 228/508 (44.88%), Query Frame = 1
Query: 187 LCLLCKKLLVNARCAPCSCRFCFTCISDYL--DKNEICPGNTEDCKQE--------LLHLNENIYVDQPMNIKISKLQVKCKEMSCDYVDELRKMEEHSRTCKYRSVACPYSNIG----------------------CDKC---------NISQDKVTDHLQSEIFAHTKLLMDFVVNFNNEMEMLKAN-------NNGLSAVNELLRN----EINELKLDGE---RRREEIAELQRKCADQAEEI--ELLNED-IPALRNVDRNVSDRLDGLQLIIEGNQVAMRAVENDFQQQIAQCATNCQQAEIKQKELIDKIGQMENKQKVDLTEMSNKIDKLSGNVDRKLLEMAANQNQLNYGEFVWKLDKFTDKMADAKNGINAIIYSESFLTHKNGFKMCLRVDPDGFGDGKGTHLSVFFCLMKGEFDGILEWPFRHSVTFALINQRTRLPHVSRTAKCADYTNNKELIQSTDRNNGFGFDQFLSLKEL-SSNPDLMRNNQIFIKCSVDID 1533
LC C +L A C R+C C+S + +KN +C + CK+E L E + D +N +IS+L+V+C + C + ++ EEH C+Y + C ++ G C KC + S++K+ +H ++ + H LL+ + M+ LKAN NG +EL N I+EL + G E+ L R E + +L+ E I L N + + L +E + + + A FQ+Q + + I+ EL KI ++ + LT+ + +L N+ L A+ + G F+WK+ + K+ D+ G +YS +F T K G+K+CLR+ +G G GKGTH+S+FF +MKG++D +L WPFRH VTF L++Q R H+ + D + D N G FL L +L S ++ + +F+KC +D +
Sbjct: 40 LCTNCNNVLKKALQTLCGHRYCSACLSWVVRNNKNPVC----QKCKEEDPSTLSEGSLLAEERAFGDAAINKEISELRVRCVTLGCSWCGTMKNFEEHQTLCEYALIPC-HTGCGHVVMRKKLADHLENGCVNNVTVCHKCKQSLSSSEYHGSKEKIKEHEKAAVGTHMLLLLQY-------MKQLKANLCSPSKAANGFIPQSELNVNGAEKSISELHIQGSLGINGNLEVDCLTRTSVPGDESVLQQLVREKLISELENKLHVFENIVAVLNKEVEASNLEITA----FQRQ-----SELDKNIIRGLEL--KIAELHHC----LTQKDAGLSRLHKNL---LFSEQASYD----GVFLWKITDVSRKLQDSVTGRAVSLYSPAFYTAKYGYKVCLRIYLNGDGTGKGTHVSLFFVVMKGDYDALLPWPFRHKVTFMLLDQNNR-EHIIDAFR-PDLASASFQRPVNDMNVASGCPTFLPLTKLQSPKHAYVKEDTLFLKCIIDTN 511
BLAST of TNF receptor-associated factor vs. TrEMBL
Match: A0A3P8ZGJ2 (TNF receptor-associated factor OS=Esox lucius OX=8010 PE=3 SV=1) HSP 1 Score: 144.05 bits (362), Expect = 2.763e-33 Identity = 124/442 (28.05%), Postives = 201/442 (45.48%), Query Frame = 1
Query: 292 CPGNTEDCKQELLHLNENIYVDQPMNIKISKLQVKCKEMSCDYVDELRKMEEHSRTCKYRSVACPYSNIGCDKCNISQDKVTDHLQSEIFAHTKLLMDFVVNFNNEMEMLKANNNGLSA--VNELLRNEINELKLD-GERRREEIAELQRKCADQAEEIELLNEDIPALRNVDRNVSDRLDGLQLIIEGNQVAMRAVENDFQQQIAQCATNCQQAEIK-----------QKELIDKIGQME--NKQ------KVDLTEMSNKIDKLSGNV---DRKLLEMAANQNQLNY----GEFVWKLDKFTDKMADAKNGINAIIYSESFLTHKNGFKMCLRVDPDGFGDGKGTHLSVFFCLMKGEFDGILEWPFRHSVTFALINQRTRLPHVSRTAKCADYTNNKELIQSTDRNNGFGFDQFLSLKELSSNPDLMRNNQIFIKCSVDI 1530
CP T +CK Y +P + K K YVD H + C C + +GCD ++ ++K+ DH ++ + H LL+ F++ +E L+ N L+ ++EL R + EL+L G+ A +Q CA L +PAL + + A+ + + ++A+ + CQ+ E+K +EL ME N+Q KV++ ++NK+ +L V D ++EM +++ G FVWK+ FT K DA G ++S +F T K G+KMCLR+ +G G G+GTHLS+FF +M+G D +L+WPF VT L++Q R H+ + D +++ +D N G F L +L S +R++ IFIK VD+
Sbjct: 156 CPERTLNCK----------YCKEPFHFKNIK-----------YVD-------HIKFCSKFRAPCRFHVVGCDT-SVEKEKIHDHERACSYEHLNLLLHFIMGIKVSLESLQPQNLELAGHKIHELHR-ALRELELKLGQLTLGVGAPVQGACAPA-----LPTPALPALTTSFTPLPSAMGA----------ALELQLHSEKTKVAELSRRCQELELKVSTFENIVCVLNRELERSCTTMEAYNRQHRLDQDKVEI--LNNKVRQLERTVGLRDLSIVEMEGKMKEMSAATFDGIFVWKISDFTKKRQDAIAGRAPAMFSPAFYTSKYGYKMCLRIYLNGDGAGRGTHLSLFFVVMRGHSDALLKWPFNQKVTLMLLDQNNR-EHIIDAFR-PDISSSSFQRPVSDMNIASGCPLFCPLPKLDSKNSYIRDDTIFIKAIVDL 548
BLAST of TNF receptor-associated factor vs. Ensembl Cavefish
Match: traf2a (TNF receptor-associated factor 2-like [Source:NCBI gene;Acc:103036375]) HSP 1 Score: 132.109 bits (331), Expect = 1.415e-32 Identity = 132/498 (26.51%), Postives = 220/498 (44.18%), Query Frame = 1
Query: 154 YESVTEIQNDMLCLLCKKLLVNARCAPCSCRFCFTCISDYLDKNEI-------CPGNTEDCK--QELLHLNENIYVDQPMNIKISKLQVKCKEMSCD---YVDELRKMEEHSRTCKYRSVACPYSNIGCDKCNISQDKVTDHLQSEIFAHTKLLMDFVVNFNNEMEMLKANNNGLSAVN-ELLRNEINELKLDGERRREEIAELQRKCADQAEEIELLNEDIPALRNVDRNVSDRLDGLQLIIEGNQVAMRAVENDFQQQIAQCATNCQQAEIK-----------QKELIDKIGQME--NKQ------KVDLTEMSNKIDKLSGNV---DRKLLEMAANQNQLNY----GEFVWKLDKFTDKMADAKNGINAIIYSESFLTHKNGFKMCLRVDPDGFGDGKGTHLSVFFCLMKGEFDGILEWPFRHSVTFALINQRTRLPHVSRTAKCADYTNNKELIQSTDRNNGFGFDQFLSLKELSSNPDLMRNNQIFIKCSVDI 1530
YE+ E Q D + + C SC+ + L NE+ CP T +CK +E H +NI + K + C + YVD ++ + C++ V GCD ++ ++K+ DH ++ + H LL+ F++ +E L+ + L++ + L + EL+L + A +Q CA L L V L+ LQL E + ++A+ + CQ+ E+K +E+ ME N+Q K+++ ++NK+ +L V D ++EM +++ G FVWK+ F+ K DA G ++S +F T K G+KMCLR+ +G G G+GTHLS+FF +M+G D +L+WPF VT L++Q R H+ + D +++ +D N G F L +L S +R++ IFIK VD+
Sbjct: 121 YEATHEGQCDFMIIPCP-----------SCK-------ELLRANELERHNERECPERTLNCKYCKEPFHF-KNIKAHDEICPKYPMICEGCAKKKIPREKYVDHIKLCTKFRTPCRFHVV-------GCDM-SVEKEKIHDHERACSYEHLNLLLHFIMGIKVNLESLQPQSLELASHKIQELHQSLRELELKMGQLSAG-APVQGACAPPPPPPPTLATSFTPLPT---TVGAALE-LQLHSE-------------KTKVAELSRRCQELELKVGTFENIVCVLNREMERSATTMEAYNRQHRLDQDKIEI--LNNKVRQLERTVGLRDLSIVEMEGKMREMSAATYDGVFVWKISDFSKKRQDAVAGRAPAMFSPAFYTSKYGYKMCLRIYLNGDGTGRGTHLSLFFVVMRGHSDALLKWPFNQKVTLMLLDQNNR-EHIIDAFR-PDISSSSFQRPVSDMNIASGCPLFCPLSKLDSKNSYIRDDTIFIKAIVDL 569
BLAST of TNF receptor-associated factor vs. Ensembl Cavefish
Match: traf2a (TNF receptor-associated factor 2-like [Source:NCBI gene;Acc:103036375]) HSP 1 Score: 117.087 bits (292), Expect = 6.686e-28 Identity = 109/380 (28.68%), Postives = 176/380 (46.32%), Query Frame = 1
Query: 400 KEMSCDYVDE---LRKMEEHSRTCKYRSVACPYSNIGCDKCNISQDKVTDHLQSEIFAHTKLLMDFVVNFNNEMEMLKANNNGLSAVNELLRNEINELKLDGERRREEIAELQRKCADQAEEIELLNEDIPALRNVDRNVSDRLDGLQLIIEGNQVAMRAVENDFQQQIAQCATNCQQAEIKQKELIDKIGQMENKQKVDLTEMSNKIDKLSGNVDRKLLEMAANQNQLNYGEFVWKLDKFTDKMADAKNGINAIIYSESFLTHKNGFKMCLRVDPDGFGDGKGTHLSVFFCLMKGEFDGILEWPFRHSVTFALINQRTRLPHVSRTAKCADYTNNKELIQSTDRNNGFGFDQFLSLKELSSNPDLMRNNQIFIKCSVDI 1530
+ ++C Y E + ++ H C + C GC K I ++K DH++ T V +M + K N + +LL + L + ++AEL R+C +E+EL + N+ + L +E + M A Q ++ Q + EI L +K+ Q+E + V L ++S I ++ G K+ EM+A G FVWK+ F+ K DA G ++S +F T K G+KMCLR+ +G G G+GTHLS+FF +M+G D +L+WPF VT L++Q R H+ + D +++ +D N G F L +L S +R++ IFIK VD+
Sbjct: 127 RTLNCKYCKEPFHFKNIKAHDEICPKYPMICE----GCAKKKIPREKYVDHIKLCTKFRTPCRFHVV---GCDMSVSKPQWNLILTPRDLLYTSFT-VPLS----QTKVAELSRRC----QELEL---KVGTFENI-------VCVLNREMERSATTMEAYNR--QHRLDQ-----DKIEI----LNNKVRQLE--RTVGLRDLS--IVEMEG----KMREMSAATYD---GVFVWKISDFSKKRQDAVAGRAPAMFSPAFYTSKYGYKMCLRIYLNGDGTGRGTHLSLFFVVMRGHSDALLKWPFNQKVTLMLLDQNNR-EHIIDAFR-PDISSSSFQRPVSDMNIASGCPLFCPLSKLDSKNSYIRDDTIFIKAIVDL 456
BLAST of TNF receptor-associated factor vs. Ensembl Cavefish
Match: traf2b (TNF receptor associated factor 2 [Source:NCBI gene;Acc:103028261]) HSP 1 Score: 113.235 bits (282), Expect = 2.420e-26 Identity = 62/202 (30.69%), Postives = 111/202 (54.95%), Query Frame = 1
Query: 955 KIGQMENKQKVD---LTEMSNKIDKLSGNVDRKLLEMAANQNQLNY-------GEFVWKLDKFTDKMADAKNGINAIIYSESFLTHKNGFKMCLRVDPDGFGDGKGTHLSVFFCLMKGEFDGILEWPFRHSVTFALINQRTRLPHVSRTAKCADYTNNKELIQSTDRNNGFGFDQFLSLKELSSNPDLMRNNQIFIKCSVDI 1530
++ + +Q++D + +SNK+ +L + + L++A ++ L G FVWK+ F+ + DA G ++S +F + K G+KMCLR+ +G G G+G+HLS+FF +M+G++D +L+WPF VT L++Q R H+ + D ++ ++ N G F L +L+ +R++ IFIK VD+
Sbjct: 329 RLEALTRQQQLDQEKIENLSNKVRQLERTLTMRDLQLAESEQALRELQFCTYDGVFVWKISDFSRRRQDALAGRAPAMFSPAFYSSKYGYKMCLRLYLNGDGTGRGSHLSLFFVVMRGKYDALLKWPFSQKVTLMLLDQNNR-EHIIDAFR-PDISSTSFQRPISEMNIASGCPLFCPLAKLAGKSSYLRDDTIFIKAIVDL 528
BLAST of TNF receptor-associated factor vs. Ensembl Cavefish
Match: traf1 (TNF receptor-associated factor 1-like [Source:NCBI gene;Acc:103045252]) HSP 1 Score: 112.079 bits (279), Expect = 5.840e-26 Identity = 101/377 (26.79%), Postives = 173/377 (45.89%), Query Frame = 1
Query: 427 ELRKMEEHSRTCKYRSVACPYSNIGCD-KCNISQDKVTDHLQSEIFAHTKLLMDFVVNFNNEMEMLKANNNGLSAVNELLRNE----INELKLDG---ERRREEIAELQRKCADQAEEIEL-LNEDIPALRNVDRNVSDRLDGLQLIIEGNQVAMRAVENDFQQQIAQCATNCQQAEIKQKELIDKIGQMENKQKVDLTEMSNKIDKLSGNVDRKLLEMAANQNQLNYGEFVWKLDKFTDKMADAKNGINAIIYSESFLTHKNGFKMCLRVDPDGFGDGKGTHLSVFFCLMKGEFDGILEWPFRHSVTFALINQRTRLPHVSRTAKCADYTNNKELIQSTDRNNGFGFDQFLSLKEL-SSNPDLMRNNQIFIKCSVD 1527
E RK + + K R C +S IGC K N DKV +H S AH LL++ V N + A++ L+N+ + ++ L+G E + + + ++ EL + + + AL+ + + + + L +E Q+ + +E D + LI + + +Q+ L +I L ++ +A Q+ G F+W++ + K+ +A G + YS +F T + GFK+C+R+ G G GKGTH+S+FF +MKG++D +L WPF+ VTF LI+Q R HV + D + ++ N G F L +L S ++++ +FIKC VD
Sbjct: 189 EKRKKDSKQESPK-RKETCVFSEIGCTFKGN--PDKVREHEVSSTSAHLHLLVEVVRNVQMSVPPPPERTVQYPALDLHLQNQDMTPLPDITLNGGELETDSGDTGANDKALSLHDDQAELEVGQQLHALQQRLQIMENIITALNREVEKTQLTVVVLERDNHNNM---------------NLIQHLEAVVAEQQQRLIRKDLQISSLQQSI-------SAQQDVSYDGTFLWRICDVSQKLKEAATGQKSSQYSPAFYTSRYGFKVCMRLYMYGDGVGKGTHISLFFVIMKGDYDPLLSWPFKQKVTFFLIDQNQR-EHVVDAFR-PDLRSASFQRPVSEMNVASGCPLFFPLSKLRSPKHAYVKDDTLFIKCVVD 538 HSP 2 Score: 49.6766 bits (117), Expect = 7.002e-6 Identity = 33/115 (28.70%), Postives = 52/115 (45.22%), Query Frame = 1
Query: 184 MLCLLCKKLLVNARCAPCSCRFCFTCISDYLDKNE--IC------PGNTEDCKQELLHLNENIYVDQPMNIKISKLQVKCKEMSCDYVDELRKMEEHSRTCKYRSVACPYSNIGC 504
LC C +L A C R+C C+ L N+ IC PG+ D ++ ++ + D +N +I +L+V C C + L+ E+H C+Y + C NIGC
Sbjct: 27 FLCSSCNNVLNEAHQTQCGHRYCRACVMWLLRNNKDLICTKCKEDPGSESD--SSMMLTLDHFFSDNAINKEIQELRVHCVNQGCGWRSTLKDFEDHQSQCEYALIPC---NIGC 136
BLAST of TNF receptor-associated factor vs. Ensembl Cavefish
Match: traf1 (TNF receptor-associated factor 1-like [Source:NCBI gene;Acc:103045252]) HSP 1 Score: 110.923 bits (276), Expect = 1.260e-25 Identity = 98/355 (27.61%), Postives = 159/355 (44.79%), Query Frame = 1
Query: 469 RSVACPYSNIGCD-KCNISQDKVTDHLQSEIFAHTKLLMDFVVNFNNEMEMLKANNNGLSAVNELLRNEINELKLDGERRREEIAELQRKCADQAEEIELLNEDIPALRNVDRNVSDRLDGLQLIIEGNQVAMRAVENDFQQQIAQCATNCQQAEIKQKELIDKIGQMENKQKVDLTEMSNKIDKLSGNVDRKLLEMAANQNQLNYGEFVWKLDKFTDKMADAKNGINAIIYSESFLTHKNGFKMCLRVDPDGFGDGKGTHLSVFFCLMKGEFDGILEWPFRHSVTFALINQRTRLPHVSRTAKCADYTNNKELIQSTDRNNGFGFDQFLSLKEL-SSNPDLMRNNQIFIKCSVD 1527
R C +S IGC K N DKV +H S AH LL++ V N + A++ L EL+ D L D E+E+ + + AL+ + + + + L +E Q+ + +E D + LI + + +Q+ L +I L ++ +A Q+ G F+W++ + K+ +A G + YS +F T + GFK+C+R+ G G GKGTH+S+FF +MKG++D +L WPF+ VTF LI+Q R HV + D + ++ N G F L +L S ++++ +FIKC VD
Sbjct: 192 RKETCVFSEIGCTFKGN--PDKVREHEVSSTSAHLHLLVEVVRNVQMSVPPPPERTVQYPALDLTLNG--GELETDSGDTGANDKALSLH--DDQAELEV-GQQLHALQQRLQIMENIITALNREVEKTQLTVVVLERDNHNNM---------------NLIQHLEAVVAEQQQRLIRKDLQISSLQQSI-------SAQQDVSYDGTFLWRICDVSQKLKEAATGQKSSQYSPAFYTSRYGFKVCMRLYMYGDGVGKGTHISLFFVIMKGDYDPLLSWPFKQKVTFFLIDQNQR-EHVVDAFR-PDLRSASFQRPVSEMNVASGCPLFFPLSKLRSPKHAYVKDDTLFIKCVVD 515 HSP 2 Score: 49.2914 bits (116), Expect = 7.595e-6 Identity = 33/115 (28.70%), Postives = 52/115 (45.22%), Query Frame = 1
Query: 184 MLCLLCKKLLVNARCAPCSCRFCFTCISDYLDKNE--IC------PGNTEDCKQELLHLNENIYVDQPMNIKISKLQVKCKEMSCDYVDELRKMEEHSRTCKYRSVACPYSNIGC 504
LC C +L A C R+C C+ L N+ IC PG+ D ++ ++ + D +N +I +L+V C C + L+ E+H C+Y + C NIGC
Sbjct: 27 FLCSSCNNVLNEAHQTQCGHRYCRACVMWLLRNNKDLICTKCKEDPGSESD--SSMMLTLDHFFSDNAINKEIQELRVHCVNQGCGWRSTLKDFEDHQSQCEYALIPC---NIGC 136
BLAST of TNF receptor-associated factor vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002130.1 (pep scaffold:Pmarinus_7.0:GL484662:8457:12718:-1 gene:ENSPMAG00000001936.1 transcript:ENSPMAT00000002130.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 110.153 bits (274), Expect = 2.146e-26 Identity = 93/372 (25.00%), Postives = 162/372 (43.55%), Query Frame = 1
Query: 436 KMEEHSRTCKYRSVACPYSNIGCDKCNISQDKVTDHLQSEIFAHTKLLMDFVVNFNNEMEM----LKANNNGLSAVNELLRNEINELKLDGERRREEIAELQRKCADQAEEIELLNEDIPALRNVDRNVSDRLD--GLQLIIEGNQVAMRAVENDFQQQIAQCATNCQQAEIKQKELIDKIGQMENKQKVDLTEMSNKIDKLSGNVDRKL--LEMAANQNQLNYGEFVWKLDKFTDKMADAKNGINAIIYSESFLTHKNGFKMCLRVDPDGFGDGKGTHLSVFFCLMKGEFDGILEWPFRHSVTFALINQRTRLPHVSRTAKCADYTNNKELIQSTDRNNGFGFDQFLSLKELSSNPDLMRNNQIFIKCSVD 1527
++ +H C + C + +GC + + V +H +S + +H L V++ N+E+E+ L+ + + ++E+L + +L+ D + E + NE + +L R D L+ + + +RA+E C C E Q++ + D L +R+L LE A G+ VWK+ + + +A +G +YS+ F T G+KMC R +G G G+GTHLS+FF +M+GE+D +LEWPFR VT +L++Q H+S T D + D N G F+S L + L+ ++ +F++ VD
Sbjct: 76 ELSQHMSACAMSTKLCGFHMLGCTFKQGTSESVREHEESAVRSHFTL----VISRNSELELQCARLQCSIEDHTNMSEMLTQRVAQLEQDLSHWSTLTGSNNTRLGSTLEMLTQHNEQLQSLHVAQRAPQRDADTAALRRDMATLRERLRALEAALGNP-GPCEERCHMHE----------------QRLTMH------DGLLDTAERRLQVLETAGYS-----GKLVWKIRDYARRKQEAASGRTLSLYSQPFYTSPFGYKMCARAYLNGDGVGRGTHLSLFFVVMRGEYDALLEWPFRRRVTLSLLDQGAARRHLSDTFT-PDPASGSFRRPDGDMNVASGCPLFVSHVALEGSSYLV-DDTVFVRVVVD 413
BLAST of TNF receptor-associated factor vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000074.1 (pep scaffold:Pmarinus_7.0:GL482142:165593:173010:-1 gene:ENSPMAG00000000066.1 transcript:ENSPMAT00000000074.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 105.145 bits (261), Expect = 1.854e-24 Identity = 55/148 (37.16%), Postives = 83/148 (56.08%), Query Frame = 1
Query: 1084 GEFVWKLDKFTDKMADAKNGINAIIYSESFLTHKNGFKMCLRVDPDGFGDGKGTHLSVFFCLMKGEFDGILEWPFRHSVTFALINQRTRLPHVSRTAKCADYTNNKELIQSTDRNNGFGFDQFLSLKELSSNPDLMRNNQIFIKCSVD 1527
G+ VWK+ + + DA +G +YS+ F T G++MC R +G G G+GTHLS+FF +M+GE+D +L WPFR VT L++Q +S T K D ++ ++D N G F+S L S ++++ IFIK VD
Sbjct: 325 GKLVWKIRDYARRKQDAVSGRTLSLYSQPFYTSPFGYRMCARAYLNGDGVGRGTHLSLFFVVMRGEYDALLPWPFRQRVTLTLLDQGAARRQLSDTFK-PDPASSSFRRPTSDMNIASGCPLFVSHVALESA-SYLQDDTIFIKVVVD 470
BLAST of TNF receptor-associated factor vs. Ensembl Sea Lamprey
Match: traf6 (TNF receptor-associated factor 6 [Source:NCBI gene;Acc:554561]) HSP 1 Score: 85.1149 bits (209), Expect = 8.463e-18 Identity = 115/532 (21.62%), Postives = 219/532 (41.17%), Query Frame = 1
Query: 148 YNYESVTEIQNDMLCLLCKKLLVNARCAPCSCRFCFTCISDYL---DKNEICPGNTEDCKQELLHLNENIYVDQPMNIKISKLQVKCKEMSCDYVDELRKMEEHSRTCKYRSVACPYSNIGCDKCN--ISQDKVTDHLQSEIFA------HTKLLMDFVVNFNNEMEMLKANNNGLSAVNELLRNEIN-ELKLDGERRREEIAELQRKCADQAEEIELLNEDIPALRNVDRNVSDRL--DGLQL----IIEGNQVAMRAVEN---------------DFQQQIA--------QCATNCQQAEIKQKELIDKIGQMENKQKVDLTEMSNKIDKLSG------NVDRKL-LEMAANQNQLNYGEFVWKLDKFTDKMAD------AKNGIN----AIIYSESFLTHKNGFKMCLRVD-------PDGFGD------GKGTHLSVFFCLMKGEFDGILEWPFRHSVTFALINQRTR-LPHVSRTAKCADYTNNKELIQSTDRN-NGFGFDQFLSLKELSSNPDLMRNNQIFIKCSV 1524
Y + +++ C +C L PC RFC CI + D CP + +LH + ++ D +I L V+C C + ELR ++EH C+Y + + C +C + + + H + E H M + + N+E N EL+R ++ L++D ++ A++ + E +++ + A + V RL +GL++ + +G Q + A + D Q A + A +C Q + +E+ + + Q + E+S K D G + R L +A ++++L G F W++++F+ + A +G++ A+++S F T G+++CLR+ P G G+ HL++F L++G++D L WPF+ + ++++Q R HV+ AD + S RN GFG+ F+ + L +R++ + ++C V
Sbjct: 51 YEADFEPPLESKYECPICLMALREPVQTPCGHRFCRACILHSMRLRDAGPKCPVDNA-----VLHEGQ-LFPDNFAKREILSLTVRCPNKPCGHRGELRALQEHQLRCEY-------AQVPCVRCEMPVCRRDLAKHEEQECMRRIVTCLHCCEKMAYKDSKNHEQMCPLVVVNCKHCQQELIREQLGPHLEVDCQQ-----AQVPCTFSPLGCEAQMVRSLLAAHMHEHTQVHMRLLANGLKILRIQVGQGAQPSSAAGSSAPPNSLSWLSSTSGGDVQTAGASRSQGSRDRAACDCAQELDRLREITRTLEERVVLQLHQIRELSAKTDNQQGLLAEATRLVRSLEARVAESESRLCAGIFTWRVERFSRLLPGGLASGFASDGMHPDAPAVMHSSGFYTGVPGYRLCLRLQVLSGREVPAGAASPSVLLAGRQPHLALFVHLLQGDYDHRLPWPFKGRIRISVVDQCERDSVHVTEMMD-ADPQLSAFQRPSVHRNPKGFGYMNFMDINTLHHR-SYLRDDCLVVRCEV 562
BLAST of TNF receptor-associated factor vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008091.1 (pep scaffold:Pmarinus_7.0:GL477915:34322:50582:-1 gene:ENSPMAG00000007312.1 transcript:ENSPMAT00000008091.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 51.2174 bits (121), Expect = 3.583e-7 Identity = 30/133 (22.56%), Postives = 60/133 (45.11%), Query Frame = 1
Query: 928 EIKQKELIDKIGQMENKQKVDLTEMSNKIDKLSGNVDRKLL----EMAANQNQLNYGEFVWKLDKFTDKMADAKNGIN--AIIYSESFLTHKNGFKMCLRVDPDGFGDGKGTHLSVFFCLMKGEFDGILEWPF 1308
+++ E + G ++ + L +++ +R +L +A +N G F+WK+ +++ +A NG I S +F T + G+++ LR+ G H+S + L G +D L WP+
Sbjct: 269 DVRVSEASTRQGNIDRDETARLQNKMARVEHSDQETERSILGLTRRLAELENTAYNGMFLWKIKHVINRLREAGNGAERPPQIDSPAFFTTRYGYRLRLRLC------RSGEHVSAYAMLGPGPYDATLAWPY 395
BLAST of TNF receptor-associated factor vs. Ensembl Sea Lamprey
Match: rnf41l (ring finger protein 41, like [Source:ZFIN;Acc:ZDB-GENE-030131-9441]) HSP 1 Score: 46.2098 bits (108), Expect = 1.368e-6 Identity = 31/113 (27.43%), Postives = 55/113 (48.67%), Query Frame = 1
Query: 163 VTEIQNDMLCLLCKKLLVNARCAPCSCRFCFTCISDYLDKNEICPGNTEDCKQELLHLNENIYVDQPMNIKISKLQVKC--KEMSCDYVDELRKMEEHSRTCKYRSVACPYSN 495
V +++ +LC +C+ +L + APC FC CI +L N CP ED ++ L +E + + M ++ L++ C + C+ V L + H + C Y CP++
Sbjct: 9 VGRVKDGLLCCVCRDVLEDPLQAPCEHAFCSACIHGWLVHNHTCP---ED--RQPLDASELRPLFRYMRNDLNALRLHCTHRARGCEGVCALETIAIHEQQCPYTPTPCPHTG 116
BLAST of TNF receptor-associated factor vs. Ensembl Nematostella
Match: EDO49464 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RG36]) HSP 1 Score: 132.494 bits (332), Expect = 3.303e-33 Identity = 135/537 (25.14%), Postives = 229/537 (42.64%), Query Frame = 1
Query: 139 MRDYNYES---VTEIQNDMLCLLCKKLLVNARCAPCSCRFCFTCISDYLDKNEICPGNTED-----------CKQELLHL-----NENIYVDQPMNIKISKLQ--------VKCKEMSCDYVDELRKMEEHSRTCKYRSVACPY-------------------SNIGCDKC---NISQDKVTDHLQSEIFAHTKLLMDFV---VNFNNEMEMLKAN--NNGLSAVNELLRNEINELKLDGERRREEIAELQRKCADQAEEIELLNEDIPALRNVDRNVSDRLDGLQLIIEGNQVAMRAVENDFQQQIAQCATNCQQAEIKQKELIDKIGQMENKQKVDLTEMSNKIDKLSGNV------DRKLLEMAANQNQL-------------NY-GEFVWKLDKFTDKMADAKNGINAIIYSESFLTHKNGFKMCLRVDPDGFGDGKGTHLSVFFCLMKGEFDGILEWPFRHSVTFALINQRTRLPHVSRTAKCADYTNNKELIQSTDRNNGFGFDQFLSLKELSSNPDLMRNNQIFIKCSVD 1527
M+D +++ V + C +C L + PC RFC C+ L CP + E+ C++E+L L N + + +++ + V+C C R +E H C+++ C Y + C C I +D++ H Q+ I +L F +F E L+ + + VN LL NE K R E A+L + ++A++ E + E AL ++N+ L +IE + R + +++I Q+ E +E ++G +EN+ S + G + DR ++A + QL +Y G ++WK+D++T + + +G IYS F + G+K C RV P+G G GKG+HLS+FF LM+GEFD +L WPFR VTF L++Q R+ + T + D T++ +++ N G F+S L + +R++ +FIK +VD
Sbjct: 1 MQDEGFQTELFVEPLDPKYRCPVCGNALKHPVQTPCGHRFCEGCLEPILRGPSKCPVDGEELKIDGVFKDVCCRREILCLACYCPNRQLGCEWMKDLQYLEEHRANCEYKGVQCHNPGCQEKVAKRDLEAHLERCEFKPSDCQYCLQRIPAASMEDHLQTCEKHPVVCPHCGAEGICRDELLHH-QTNICEQAELPCSFAKHGCHFKGTREALETHFRDQASVHVNLLLTATQNEEKA----RSEMAAKLSQMEKERAKQQEQMYEQREALAVANQNLRTYQGKLN-VIERSVAEQRRELAELKERI-----QLQEVEAAIREQDRRLGMIENEASRGAAPSSGP-GSMGGTMALERRQDRNEHQLALHDIQLAEHDLKLQMLEATSYDGTYIWKIDEYTRRYQEGVSGKTPSIYSPPFYVGRYGYKACARVYPNGDGMGKGSHLSLFFVLMRGEFDALLPWPFRQKVTFKLLDQ-DRVHDIGDTFR-PDPTSSSFKRPTSNMNIASGCPLFISHTNLQTR-AYVRDDTMFIKIAVD 522
BLAST of TNF receptor-associated factor vs. Ensembl Nematostella
Match: EDO35237 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SM27]) HSP 1 Score: 123.25 bits (308), Expect = 3.763e-30 Identity = 98/369 (26.56%), Postives = 169/369 (45.80%), Query Frame = 1
Query: 427 ELRKMEEHSRTCKYRSVACPYSNIGCDKCNISQDKVTDHLQSEIFAHTKLLMDFVVNFNNEMEMLKANNNGLSAVNELLR--NEINELKLDGERRREEIAELQRKCADQAEEIELLNEDIPALRNVDRNVSDRLDGLQLIIEGNQVAMRAVENDFQQQIAQCATNCQQAEIKQKELIDKIGQMENKQKVDLTEMSNKIDKLSGNVDRKLLEMAANQNQLNYGEFVWKLDKFTDKMADAKNGINAIIYSESFLTHKNGFKMCLRVDPDGFGDGKGTHLSVFFCLMKGEFDGILEWPFRHSVTFALINQRTRLPHVSRTAKCADYTNNKELIQSTDRNNGFGFDQFLSLKELSSNPDLMRNNQIFIKCSVD 1527
E +K+ H+R C C +S +GC + + + +H + H LL + N L N+L R E K + ER + E A+++ + DQ + ++ + + + + R D L+ +V MR + + C + +K+ E+ D NK L+++ + I + ++ L + Q G F+WK+DKFT++ A+AK+G IYS F TH+ G+K+C R+ P+G G + +LS+F LM+GE+D IL WPF+ ++T LI+Q + ++S T D + + + N G +F S L + M N +F+K VD
Sbjct: 173 ERKKLSAHTRECPNALTDCRFSPLGCTY-KVKKIALREHQNKHVIKHMILL---------GRTTGEPQPNLLELENQLERFDGENTSFKTELERHKYEFAQMKERFNDQNARLGIVEKTVANQKGDIAEIWMRFDQENLV---GEVRMRDKLKK-FKVKTKANKECLLSLMKRLEVQDDSQTNPNKLNRRLSQLESSITIHKTKLFQEDLRIQIQQAISYDGTFLWKIDKFTERYAEAKSGNATSIYSSPFYTHRFGYKLCARLFPNGDGSARDNYLSIFIALMRGEYDSILPWPFQETITITLIDQDNGM-NISETFD-PDPCSISFQRPTRNINVASGCPRFCSQTVLRTR-GYMNENCVFVKVVVD 524
BLAST of TNF receptor-associated factor vs. Ensembl Nematostella
Match: EDO38873 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SBN4]) HSP 1 Score: 117.087 bits (292), Expect = 3.476e-28 Identity = 114/481 (23.70%), Postives = 208/481 (43.24%), Query Frame = 1
Query: 166 TEIQNDMLCLLCKKLLVNARCAPCSCRFCFTCISDYLDKNEICPGNTEDCKQELLHLNENIYVDQPMNIKISKLQVKC--KEMSCDYVDELRKMEEHSRTCKYRSVACPYSNIGCDKCNISQDKVTDHLQSEI--------FAHTKLLMDFVVNFNNEMEMLKANNNGLSAVNELLRNEINELKLDGERRREEIAELQRKCADQAEEIELLNEDIPALRNVDRNVSDRLDGLQLIIEGNQVAMRAVENDFQQQIAQCATNCQQAEI---KQKELIDKIGQMENKQKVDLTEMSNKIDKL----------SGNVDRKLLEMAANQNQLNYGEF----VWKLDKFTDKMADAKNGINAIIYSESFLTHKNGFKMCLRVDPDGFGDGKGTHLSVFFCLMKGEFDGILEWPFRHSVTFALINQRTRLPHVSRTAKCADYTNNKELIQSTDRNNGFGFDQFLSLKELSSNPDLMRNNQIFIKCSVD 1527
T I LC C+ ++ +A C R+C CIS L + P + C + + D+ + +I +L V C + C + ELR + H C++ ++C + G +S K+ +HLQ+E + +++ + ++E N EL+R E++ E R E+ R C + E +E I L + ++GLQ + + A+ D +++A E+ + +D++ + + V L E + I +L +G + + ++ N L F +WK+ +K ++A +G YS F T +G+KMC R+ +G G G+ H+S+FF +M+GEFD +L WPFR VT L++Q + HV + D +++ + N G F S ++L+ + +R++ +F+K VD
Sbjct: 16 TAIAAKHLCAKCRLIVKDAVQTACGHRYCSPCISPLLSRG---PIQCDVCGSTIT--KPETFRDKFADREILELHVHCVNQPHGCPWEGELRHRQNHHTKCEFNPISCVHPECGK---KLSVAKLPEHLQNECQYREETCSYCEQPVVVARMKE-HHEKTCPSYPVNCPKCSKELIRVEVHSTPFTREPRLEK----GRGCENTLEVLEDHESRIKKLEQRGGGIG--VNGLQSMRISENIDNEAI-GDVLRRVANVEAKGADHEVLVVEAHSAVDELRREVGRLNVKLQESDDIIRRLERQLELHDQGTGLRNLAIADLEERLNTLQGTTFDSVLLWKITNVANKRSEATSGRVTSFYSPCFFTGPHGYKMCARIYLNGDGMGRNHHVSLFFVIMRGEFDALLRWPFRQKVTLMLLDQ-DNVEHVIDAFR-PDPSSSSFQRPRAEMNIASGCPLFCSHEQLTQH-AYIRDDTMFLKIIVD 477
BLAST of TNF receptor-associated factor vs. Ensembl Nematostella
Match: EDO48773 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RI91]) HSP 1 Score: 116.701 bits (291), Expect = 4.785e-28 Identity = 114/466 (24.46%), Postives = 198/466 (42.49%), Query Frame = 1
Query: 190 CLLCKKLLVNARCAPCSCRFCFTCISDYL-DKNEICP-GNTEDCKQELLHLNENIYVDQPMNIKISKLQVKCKEMSCDYVDELRKMEEHSRTCKYRSVACPYSNIGCDKCN-ISQDKVTDHLQSEIFAHTKLLMDFV---VNFNNEMEMLKANNNGLSAVNELLRNEINELKLDGERRREEIAELQRKCADQAEEIELLNEDIPALRNVDRNVSDRLDGLQLIIEGNQVAMRAVENDFQQQIAQCATNCQQAEIKQKELIDKIGQMENKQKVDLTEMSNKIDKLSGNVDRKLLEMAANQNQLNY-----------GEFVWKLDKFTDKMADAKNGINAIIYSESFLTHKNGFKMCLRVDPDGFGDGKGTHLSVFFCLMKGEFDGILEWPFRHSVTFALINQR----TRLPHVSRTAKCADYTNNKELIQSTDRNNGFGFDQFLSLKELSSNPDLMRNNQIFIKCSV 1524
C +C L + PC RFCF CI + D CP NT ++EL N + + M I ++K KE C + L+++EEH + C CP ++C + Q K D +E + + D V + E LK G ++ NE A +QRK D+ N +P D ++ Q + E+ + + Q A ++++ +D +G ++ + L + K++ + + DR++ E+ +L G F+WKLD F + G+ A I+S F T G+KMCLR++ +G G G H+S+F +M+G++DGILEWPF +T ++++Q +R P +S T + S + G+G+ +F + +L+ ++NN I ++ +
Sbjct: 58 CPICLLGLRDPVQTPCGHRFCFNCIRRSIRDAGPKCPVDNTPLSERELYRDN---FAKREMMSFIVWCRLK-KERGCTWKGALKELEEHLKGCPCMDTNCP------NECGAVMQRKEVDKHCAEACPNRSVPCDHCKMKVTISKIEEHLK----GCPCMDTNCPNECG-------------AVMQRKEVDKHCAEACPNRSVPC------------DHCKMKSSKEQASHGPQEHTPHEAELRREALFQSANMQRE--VDMLGSRGDEYRQFLAYLERKVEDVKTSSDRRIAELTHKLMRLETREIELEGRVCNGTFIWKLDNFRQCREGSIAGLTAAIHSPPFYTSMYGYKMCLRMNLNGVDGGLGEHVSLFIHMMQGDWDGILEWPFIGRITLSILDQSDQIDSRRP-ISETLVAKPNLLAFQRPTSPRNHKGYGYVEFCPIDQLTEG-QYIKNNSILVRIQI 480
BLAST of TNF receptor-associated factor vs. Ensembl Nematostella
Match: EDO41243 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S4Z7]) HSP 1 Score: 112.079 bits (279), Expect = 1.322e-26 Identity = 115/472 (24.36%), Postives = 196/472 (41.53%), Query Frame = 1
Query: 118 LENVGQIMRDYNYESVTEIQNDMLCLLCKKLLVNARCAPCSCRFCFTCISDYLDKNEI--CPGNTEDCKQELLHLNENIYVDQPMNIKISKLQVKCKEMSCDYVDELRKMEEHSRTCKYRSVACPYSNIGCDKCNISQDKVTDHLQSEIFAH----------TKLLMDFVVNFNNEMEMLKANNNGLSAVNELLRNEINELKLDGERRREEIAELQRKCADQAEEIELLNEDIPALRNVDRNVSDRLDGLQLIIEGNQVAMRAVEN----DFQQQIAQCATNCQQAEIK-QKELIDKIGQMENKQKVDLTEMSNKIDKLSGNVDRKLLEMAANQNQLNYGEFVWKLDKFTDKMADAKNGINAIIYSESFLTHKNGFKMCLRVDPDGFGDGKGTHLSVFFCLMKGEFDGILEWPFRHSVTFALINQRTRLPHVSRTAKCADYTNNKELIQ--STDRNNGFGFDQFLSLKELSS 1476
+ + + Y+ E V + + C +C L C RFC C+ + + CP + +E L L +++++D+ I VKC C + ELR +E H+R C Y V C SN C + + V +HL E + + N + +++ +N SA +L R +++E L R + E C D++ L+ N D+ L G Q+ + + + Q + CA E++ Q L+D+ + +++T + + SG +L + N+L FVW++ F D + AK G+ + SE F T KNG+K+ + P+G GK TH+S F + +GE+DGIL WPF + L++Q+ + K + E T NNG G F+S ++L +
Sbjct: 1 MADPSPVPSGYDSEFVIAVAEEYTCRICHLPLRVPVQTKCGHRFCKECLDEASRRKSRAECPMD-----REPLDLKKDVFLDKAAERTILSFLVKCPCKGCKWEAELRDLEAHARNCDYELVTC--SNPMCSA-QLPRMDVDEHLLVECDWRLIVCEYCGDESPYCLQKAHARNCDYKLVTCSNPMCSA--QLPRMDVDEHLLVECDWRLIVCEY---CGDESPY---------CLQKDHSNQCDKFPVLCPNDCGTQITREKLRDHQSEECQFAVVPCAFRDFGCEVEIQNRLMDQHLDTNIQSHLNMTCNQLLLSRDSGAQFHELQQGLGRVNELLKMRFVWRIPDFADSLRQAKLGLKVRLDSEPFFTEKNGYKLRATLYPNGTMSGKNTHISAFVSINRGEYDGILAWPFTRVIKITLLDQKENVLQRRNVEKTIIPNPSLENFHRPKTVSNNGRGSATFVSHEKLWT 450
BLAST of TNF receptor-associated factor vs. Ensembl Medaka
Match: ENSORLT00000020861.2 (TNF receptor-associated factor 2 [Source:NCBI gene;Acc:101167626]) HSP 1 Score: 131.724 bits (330), Expect = 2.267e-32 Identity = 112/405 (27.65%), Postives = 185/405 (45.68%), Query Frame = 1
Query: 418 YVDELRKMEEHSRTCKYRSVACPYSNIGCDKCNISQDKVTDHLQSEIFAHTKLLMDFVVNFNNEMEMLKANNNGLSAVNELLRNEINELKLDGERR-----REEIAELQRKCADQ-AEEIELLNEDIPALRNVDRNVSDRLDGLQLIIEGNQVAMRAVENDFQQQIAQCATNCQQAEIK-----------QKELIDKIGQME--NKQ------KVDLTEMSNKIDKLSGNV---DRKLLEMAANQNQLNY----GEFVWKLDKFTDKMADAKNGINAIIYSESFLTHKNGFKMCLRVDPDGFGDGKGTHLSVFFCLMKGEFDGILEWPFRHSVTFALINQRTRLPHVSRTAKCADYTNNKELIQSTDRNNGFGFDQFLSLKELSSNPDLMRNNQIFIKCSVDIDS 1536
YVD ++ + C++ V GCD ++ ++K+ DH + + H LL+ F++ +E L+ L ++ L +E+++ D E R R A LQ CA A L+ + A L+L ++ + ++A+ + CQ+ E+K +EL ME N+Q K+++ +SNK+ +L V D ++EM ++ G F+WK+ FT K DA G ++S +F T K G+KMCLR+ +G G G+GTHLS+FF +M+G D +L+WPF VT L++Q R H+ + D +++ +D N G F L +L S +R+ IFIK VD+
Sbjct: 203 YVDHIKFCSKFKAPCRFHVV-------GCDT-SVEKEKIHDHERQCSYEHLNLLLHFIMGIKVSLESLQPQR--LEVASQKL-HELHQSLRDLELRMSQLGRSGTAPLQGVCAATLATSFTPLHSAMGA-------------ALELQLQSEKT-----------KVAELSRRCQELELKVSTFENIVCILNRELERSCATMEAYNRQHRLDQDKIEI--LSNKVRQLERTVSLRDLSIVEMEGKMKDMSAATYDGIFIWKISDFTKKRQDAMAGRAPAMFSPAFYTSKYGYKMCLRIYLNGDGTGRGTHLSLFFVVMRGHSDALLKWPFNQKVTLMLLDQNNR-EHIIDAFR-PDISSSSFQRPVSDMNIASGCPLFCPLSKLDSKNSYIRDETIFIKAIVDLSG 568
BLAST of TNF receptor-associated factor vs. Ensembl Medaka
Match: traf3 (TNF receptor associated factor 3 [Source:NCBI gene;Acc:101161601]) HSP 1 Score: 123.635 bits (309), Expect = 4.075e-30 Identity = 110/450 (24.44%), Postives = 192/450 (42.67%), Query Frame = 1
Query: 190 CLLCKKLLVNARCAPCSCRFCFTCISDYLD-KNEICPGNTEDCKQELLHLNENIYVDQPMNIKISKLQVKCKEMS--CDYVDELRKMEEHSRTCKYRSVACPYSNIGCDKCNISQDKVTDHLQSEIFAHTKLLMDFVVNFNNEMEMLKANNNGLSAVNELLRNEINELKLD-GERRREEIAELQRKCADQAEEIELLNEDIPALRNVDRNVSDRLDGLQLIIEGNQVAMRAVENDFQQQIAQCATNCQQAEIKQKELIDKIGQMENKQKVDLTEMSNKIDKLSGNVDRKLLEMAANQNQLNYGEFVWKLDKFTDKMADAKNGINAIIYSESFLTHKNGFKMCLRVDPDGFGDGKGTHLSVFFCLMKGEFDGILEWPFRHSVTFALINQRTRLPHVSRTAKCADYTNNKELIQSTDRNNGFGFDQFLSLKELSSNPDLMRNNQIFIKCSVD 1527
C C+ +L R C RFC++CI+D L N +CP + E + I+ D + +I L+V C+ + C L+++ +H C + V CP +G K + + ++ +HL + + + +F N E+ K A N L E+ E + + + L +++ +LR V RL L+ +G + ++ + +++ M + ++ L +M + ++LE A+ G +WK+ + + DA G +YS+ F T G+KMC RV +G G GKGTHLS+FF +M+GE+D +L WPF+ VT L++Q H+ K D +++ + N G F+S L S ++++ IFIK +VD
Sbjct: 48 CEACRLVLCQPRQTECGHRFCYSCINDILSCPNPVCPADMEPL------FKDKIFRDVCCHREIMALKVYCRSEANGCQEQMSLQQIPDHVNVCPFFEVPCP---LGKCKERMMRKEIPEHLAWKC-KYRESTCEFCKNKMPLTELQKHKETVCPAFPVSCPNHCTSSSLPRSEKLMSSHTEKLLELELELRSLRQLRDEMESLRGTLDTVRTRLSALE---QGGRASL-------------------------ETQLNRHDDMLSVHEIRLADMDLRF---------QVLETASYN-----GTLIWKIRDYKRRKQDAVAGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVVMRGEYDALLPWPFKQKVTLMLMDQGPSRKHLGDAFK-PDPSSSSFRRPVAEMNIASGCPLFVSQSVLESG-TYIKDDTIFIKVTVD 443
BLAST of TNF receptor-associated factor vs. Ensembl Medaka
Match: traf4a (TNF receptor associated factor 4 [Source:NCBI gene;Acc:101161428]) HSP 1 Score: 122.094 bits (305), Expect = 1.460e-29 Identity = 114/511 (22.31%), Postives = 221/511 (43.25%), Query Frame = 1
Query: 139 MRDYNYESVTEIQNDMLCLLCKKLLVNA-RCAPCSCRFCFTCISDYLDKNEICPGNTEDCKQELLHLN-ENIYVDQPMNIKISKLQVKC--KEMSCDYVDELRKMEEHSRTCKYRSVA---------------------CPYSNIGCDKCN--ISQDKVTDH----LQSEIFAHTKL---LMDFVVNFNNEMEMLKANNNGLSAVNELLRNEINELKLDGERRREEIAELQRKCADQAEEIELLNEDIPALRNVDRNVSDRLDGLQLIIEGNQVAMRAVENDFQQQIAQCATNCQQAEIKQKELIDKIGQMENKQKVDLTEMSNKIDKLSGNV---DRKLLEMAANQNQLNYGEFVWKLDKFTDKMADAKNGINAIIYSESFLTHKNGFKMCLRVDPDGFGDGKGTHLSVFFCLMKGEFDGILEWPFRHSVTFALINQR----TRLPHVSRTAKCADYTNNKELIQSTDRNN------GFGFDQFLSLKELSSNPDLMRNNQIFIKCSVDI 1530
M ++Y+ + + + C LC K + + + C RFC TC+ ++L + C ++ L L+ IY D + +I L ++C E C + ++++++ H TC + + CP + C+ C + + +H Q ++ K +M +++ + E K E + + I + R +C +Q + ED+ +V D G+ + + ++ A C C + I + +E+ K LT M N + + + R++ E++ + + G +WKL+ ++ K+ +AK N +S F TH+ G+K+ + +G G G+G+HLSV+ ++ GE+D +LEWPF + VTF++++Q ++ H++ T N + ST RN+ GFG+ +F+S +E+ + +R+N IFIK S++I
Sbjct: 1 MPGFDYKFLEKPKRRFQCPLCSKAMREPVQVSTCGHRFCDTCLQEFLSEGVF------KCPEDQLPLDYAKIYPDPELEQQILSLPIRCIHSEEGCRWTGQMKQLQGHFSTCAFNVIPCPNRCSVKLTRRDLPDHLQHDCPKRKVKCEFCGSEFTGEAFENHQGVCPQESVYCENKCGARMMRRLLSQHGMAECPKRTQPCKYCGKEFVFDTIQNHQFHCPR-------FPVQCPNQCGTPNIAREDL------ANHVKDNC--------GSALVLCPFKD------AGCKHRCPKLAIGR--------HLEDTTKSHLTMMCNLVSRQRQEILELRREMEELSVSHD----GVLIWKLNDYSRKLQEAKLRSNHEFFSPPFYTHRYGYKLQVSAFLNGNGSGEGSHLSVYIRVLPGEYDNLLEWPFSYKVTFSILDQSDPSLSKPQHITETFNPDPNWKNFQKPCST-RNSLDESTLGFGYPKFISHEEIKKR-NYIRDNCIFIKASIEI 464
BLAST of TNF receptor-associated factor vs. Ensembl Medaka
Match: traf4a (TNF receptor associated factor 4 [Source:NCBI gene;Acc:101161428]) HSP 1 Score: 122.094 bits (305), Expect = 2.182e-29 Identity = 117/528 (22.16%), Postives = 227/528 (42.99%), Query Frame = 1
Query: 139 MRDYNYESVTEIQNDMLCLLCKKLLVNA-RCAPCSCRFCFTCISDYLDKNEICPGNTEDCKQELLHLN-ENIYVDQPMNIKISKLQVKC--KEMSCDYVDELRKMEEHSRTCKYRSVA---------------------CPYSNIGCDKCN--ISQDKVTDH----LQSEIFAHTKL---LMDFVVNFNNEMEMLKANNNGLSAVNELLRNEINELKLDGERRREEIAELQRKCADQAEEIELLNEDIPALRNVDRNVSDRLDGLQLIIEGNQVAMRAVENDFQQQIAQCATNCQQAEIKQKELIDKIGQMENKQKVDLTEMSNKIDKLSGNV---DRKLLEMAANQNQLNYGEFVWKLDKFTDKMADAKNGINAIIYSESFLTHKNGFKMCLRVDPDGFGDGKGTHLSVFFCLMKGEFDGILEWPFRHSVTFALINQR----TRLPHVSRTAKCADYTNNKELIQSTDRNN------GFGFDQFLSLKELSSNPDLMRNNQIFIKCSVDIDS*LNYIFIVINKFAHL 1581
M ++Y+ + + + C LC K + + + C RFC TC+ ++L + C ++ L L+ IY D + +I L ++C E C + ++++++ H TC + + CP + C+ C + + +H Q ++ K +M +++ + E K E + + I + R +C +Q + ED+ +V D G+ + + ++ A C C + I + +E+ K LT M N + + + R++ E++ + + G +WKL+ ++ K+ +AK N +S F TH+ G+K+ + +G G G+G+HLSV+ ++ GE+D +LEWPF + VTF++++Q ++ H++ T N + ST RN+ GFG+ +F+S +E+ + +R+N IFIK S++I I +++ F L
Sbjct: 1 MPGFDYKFLEKPKRRFQCPLCSKAMREPVQVSTCGHRFCDTCLQEFLSEGVF------KCPEDQLPLDYAKIYPDPELEQQILSLPIRCIHSEEGCRWTGQMKQLQGHFSTCAFNVIPCPNRCSVKLTRRDLPDHLQHDCPKRKVKCEFCGSEFTGEAFENHQGVCPQESVYCENKCGARMMRRLLSQHGMAECPKRTQPCKYCGKEFVFDTIQNHQFHCPR-------FPVQCPNQCGTPNIAREDL------ANHVKDNC--------GSALVLCPFKD------AGCKHRCPKLAIGR--------HLEDTTKSHLTMMCNLVSRQRQEILELRREMEELSVSHD----GVLIWKLNDYSRKLQEAKLRSNHEFFSPPFYTHRYGYKLQVSAFLNGNGSGEGSHLSVYIRVLPGEYDNLLEWPFSYKVTFSILDQSDPSLSKPQHITETFNPDPNWKNFQKPCST-RNSLDESTLGFGYPKFISHEEIKKR-NYIRDNCIFIKASIEIP---QKIMVILKCFIKL 478
BLAST of TNF receptor-associated factor vs. Ensembl Medaka
Match: unm_sa808 (TNF receptor-associated factor 2 [Source:NCBI gene;Acc:101155367]) HSP 1 Score: 120.168 bits (300), Expect = 2.057e-28 Identity = 114/455 (25.05%), Postives = 192/455 (42.20%), Query Frame = 1
Query: 292 CPGNTEDCK--QELLHLNENIYVDQPMNIKISKLQVKCKEMSCD---YVDELRKMEEHSRTCKYRSVACPYSNIGCDKCNISQDKVTDHLQSEIFAHTKLLMDFVVNFNNEMEMLKANNNGLSAVNELLRNEINELKLDGERRREEIAELQRKCADQAEEIELLNEDIPALRNVDR-------------NVSDRLDGLQLIIEGNQVAMRAVENDFQQQIAQCATNCQQAEIK-------------QKELIDKIGQMENKQ-KVD---LTEMSNKIDKLSGNVDRKLLEMAANQNQLNY-------GEFVWKLDKFTDKMADAKNGINAIIYSESFLTHKNGFKMCLRVDPDGFGDGKGTHLSVFFCLMKGEFDGILEWPFRHSVTFALINQRTRLPHVSRTAKCADYTNNKELIQSTDRNNGFGFDQFLSLKELSSNPDLMRNNQIFIKCSVDI 1530
CP T +CK +E H +NI + K + C + YVD H + C C + +GCD ++ ++K+ DH ++ + H LL+ +++ ME L+ GL L E+ + D E R +++ Q + +VS L + A+ + + ++A+ C + E+K + E + N+Q K+D + +SNK+ +L V K L +A + +L G F+W++ F K DA G ++S +F T K G+KMCLR+ +G G G+GTHLS+FF +M+G D +L+WPF VT L++Q R H+ + D T++ ++ N G F L +L + +R++ IFIK VD+
Sbjct: 156 CPERTLNCKYCKEPFHF-KNIKAHDEICPKYPMICEGCAKKKIPREKYVD-------HIKFCSKFRTPCRFHVVGCDM-SVEKEKIHDHERAFAYEHLNLLLHYIMGMKVSMEGLQPQ--GLETAGHKL-VELQKSLRDLEARVSQLSTTSSGPPVQGAAASSSSSSSGPPGPPASVPLPPPPTLPPTLSVSTSFTPLPSSV---GAALELQLHSEKTKVAELGRRCTELEVKSGTFENVVCVLNREVERFTTTMEASNRQHKLDQDKIEALSNKVRQLERTVGLKDLTVAEMEGRLREMAATTFDGVFIWRISDFAKKRQDAVAGRAPAMFSPAFYTSKYGYKMCLRIYLNGDGTGRGTHLSLFFVVMRGLSDALLKWPFNQKVTLMLLDQSNR-EHIIDAFR-PDVTSSSFQRPVSEMNIASGCPLFCPLSKLDAKNSYIRDDTIFIKAIVDL 593
BLAST of TNF receptor-associated factor vs. Planmine SMEST
Match: SMESG000025980.1 (SMESG000025980.1) HSP 1 Score: 858.596 bits (2217), Expect = 0.000e+0 Identity = 432/479 (90.19%), Postives = 450/479 (93.95%), Query Frame = 1
Query: 103 MSGSKLENVGQIMRDYNYESVTEIQNDMLCLLCKKLLVNARCAPCSCRFCFTCISDYLD-KNEICPGNTEDCKQELLHLNENIYVDQPMNIKISKLQVKCKEMSCDYVDELRKMEEHSRTCKYRSVACPYSNIGCDKCNISQDKVTDHLQSEIFAHTKLLMDFVVNFNNEMEMLKANNNGLSAVNELLRNEINELKLDGERRREEIAELQRKCADQAEEIELLNEDIPALRNVDRNVSDRLDGLQLIIEGNQVAMRAVENDFQQQIAQCATNCQQAEIKQKELIDKIGQMENKQKVDLTEMSNKIDKLSGNVDRKLLEMAANQNQLNYGEFVWKLDKFTDKMADAKNGINAIIYSESFLTHKNGFKMCLRVDPDGFGDGKGTHLSVFFCLMKGEFDGILEWPFRHSVTFALINQRTRLPHVSRTAKCADYTNNKELIQSTDRNNGFGFDQFLSLKELSSNPDLMRNNQIFIKCSVDIDS 1536
MSGSKLENVGQIMRDYNYESVTEIQNDMLCLLCKKLLVNARCAPCSCRFCFTCISD+LD K + CPGNTE+CKQE+LHLNENI VD PMN+KI+KLQVKCKEMSCDYVDELRKME+HSRTCKYRSVACPYSNIGCDKCNISQDKVTDHLQSEIF HTKLLMDFVVNFNNEME+LKANNNGLS VNELLRNEINELKLDG+RRR EI +LQRKCA+QAEEIELLNEDIPALRNVDRNVSDRLDGLQLIIEGNQVAMRAVENDFQQQIAQCATNCQQAEIKQKELIDKIGQMENKQKVDLTEMSNKIDKLSGNVDRKLLEMAANQNQ GEF+WKLDKFTDKMADAK GINA IYSESFLTHKNGFKMCL V PDG G GKG HLSVFF LMKGEFDGILEWPFRHSVTFALINQRTRLPHVS+ +CA+Y NNKE IQ TDRN G GF +F+S +ELSSNPDLMRNNQIFIKCSVDIDS
Sbjct: 1 MSGSKLENVGQIMRDYNYESVTEIQNDMLCLLCKKLLVNARCAPCSCRFCFTCISDFLDHKKKNCPGNTEECKQEMLHLNENICVDYPMNMKIAKLQVKCKEMSCDYVDELRKMEDHSRTCKYRSVACPYSNIGCDKCNISQDKVTDHLQSEIFVHTKLLMDFVVNFNNEMEILKANNNGLSPVNELLRNEINELKLDGDRRRVEIGDLQRKCANQAEEIELLNEDIPALRNVDRNVSDRLDGLQLIIEGNQVAMRAVENDFQQQIAQCATNCQQAEIKQKELIDKIGQMENKQKVDLTEMSNKIDKLSGNVDRKLLEMAANQNQRINGEFMWKLDKFTDKMADAKKGINAFIYSESFLTHKNGFKMCLSVYPDGDGGGKGNHLSVFFHLMKGEFDGILEWPFRHSVTFALINQRTRLPHVSKITECANYPNNKEFIQPTDRNAGRGFARFVSHEELSSNPDLMRNNQIFIKCSVDIDS 479
BLAST of TNF receptor-associated factor vs. Planmine SMEST
Match: SMESG000025794.1 (SMESG000025794.1) HSP 1 Score: 823.543 bits (2126), Expect = 0.000e+0 Identity = 412/479 (86.01%), Postives = 426/479 (88.94%), Query Frame = 1
Query: 103 MSGSKLENVGQIMRDYNYESVTEIQNDMLCLLCKKLLVNARCAPCSCRFCFTCISDYLD-KNEICPGNTEDCKQELLHLNENIYVDQPMNIKISKLQVKCKEMSCDYVDELRKMEEHSRTCKYRSVACPYSNIGCDKCNISQDKVTDHLQSEIFAHTKLLMDFVVNFNNEMEMLKANNNGLSAVNELLRNEINELKLDGERRREEIAELQRKCADQAEEIELLNEDIPALRNVDRNVSDRLDGLQLIIEGNQVAMRAVENDFQQQIAQCATNCQQAEIKQKELIDKIGQMENKQKVDLTEMSNKIDKLSGNVDRKLLEMAANQNQLNYGEFVWKLDKFTDKMADAKNGINAIIYSESFLTHKNGFKMCLRVDPDGFGDGKGTHLSVFFCLMKGEFDGILEWPFRHSVTFALINQRTRLPHVSRTAKCADYTNNKELIQSTDRNNGFGFDQFLSLKELSSNPDLMRNNQIFIKCSVDIDS 1536
MSGSKLENV QIMRDYNYESVTEIQNDMLC LCKKLLVNARCAPC CRFCFTCISD+LD K +ICPG+TE+CKQE+LHLNENI VD PMNIKISKLQVKCKEMSC YVDELRKME+HSRTCKYRSVACPYSNIGCDKCNISQDKVTDHLQSEIFAHTKLLMDFVVNFNNEMEMLKANNNGLSAVNELLRNEINELKLDGERRR EIA+LQRKCADQAEEIELLNEDIPALRNVDRNVSDRLDGLQLIIEGN QKELIDKIGQMENKQKVDLTEMSNKIDKLSGNVDRKLLEMAANQNQ GEF+WKLDKFTDKMADAKNGIN IYSESFLTHKNGFKMCLRVDPDG G GKGTHLSVFF LMKGEFDGILEWPFRHSVTFALINQRTRLPHVS+T KCA+Y N+K LIQ TDRN G GF +F+S +ELSSNPDLMRNNQIFIKCSVDIDS
Sbjct: 1 MSGSKLENVWQIMRDYNYESVTEIQNDMLCFLCKKLLVNARCAPCGCRFCFTCISDFLDHKEKICPGDTEECKQEMLHLNENICVDYPMNIKISKLQVKCKEMSCVYVDELRKMEDHSRTCKYRSVACPYSNIGCDKCNISQDKVTDHLQSEIFAHTKLLMDFVVNFNNEMEMLKANNNGLSAVNELLRNEINELKLDGERRRVEIADLQRKCADQAEEIELLNEDIPALRNVDRNVSDRLDGLQLIIEGN----------------------------QKELIDKIGQMENKQKVDLTEMSNKIDKLSGNVDRKLLEMAANQNQRINGEFMWKLDKFTDKMADAKNGINTRIYSESFLTHKNGFKMCLRVDPDGNGGGKGTHLSVFFHLMKGEFDGILEWPFRHSVTFALINQRTRLPHVSKTVKCANYPNDKALIQPTDRNAGLGFPKFVSHEELSSNPDLMRNNQIFIKCSVDIDS 451
BLAST of TNF receptor-associated factor vs. Planmine SMEST
Match: SMESG000025934.1 (SMESG000025934.1) HSP 1 Score: 796.579 bits (2056), Expect = 0.000e+0 Identity = 389/404 (96.29%), Postives = 393/404 (97.28%), Query Frame = 1
Query: 103 MSGSKLENVGQIMRDYNYESVTEIQNDMLCLLCKKLLVNARCAPCSCRFCFTCISDYLDKNEICPGNTEDCKQELLHLNENIYVDQPMNIKISKLQVKCKEMSCDYVDELRKMEEHSRTCKYRSVACPYSNIGCDKCNISQDKVTDHLQSEIFAHTKLLMDFVVNFNNEMEMLKANNNGLSAVNELLRNEINELKLDGERRREEIAELQRKCADQAEEIELLNEDIPALRNVDRNVSDRLDGLQLIIEGNQVAMRAVENDFQQQIAQCATNCQQAEIKQKELIDKIGQMENKQKVDLTEMSNKIDKLSGNVDRKLLEMAANQNQLNYGEFVWKLDKFTDKMADAKNGINAIIYSESFLTHKNGFKMCLRVDPDGFGDGKGTHLSVFFCLMKGEFDGILEWPFRH 1314
MSGSKLENV QIMRDYNYESVTEIQNDMLCLLCKKLLVNARCAPCSCRFCFTCISDYLDKNEICPGNTEDCKQE+L+LNENIYVDQPMNIKISKLQVKCKEMSCDYVDELRKMEEHSR CKYRSVACPYSNIGCDKCNISQDKVTDHLQSEIFAHTKLLMDFVVNF+NEMEMLKANNNGLSAVNELLRNEINELKLDGERRREEIAELQ KCADQAEEIELLNEDIPALRNVDRNVSDRLDGLQLIIEGNQVAMRAVENDFQQQIAQCATNCQQAEIKQKELIDKIGQMENKQKVDLTEMSNKIDK SGNVDRKLLEMAANQNQ GEF+WKLDKFTDKMADAK GINAIIYSESFLTHKNGFKMCLRVDPDG G GKGTHLSVFFCLMKGEFDGILEWPF H
Sbjct: 1 MSGSKLENVWQIMRDYNYESVTEIQNDMLCLLCKKLLVNARCAPCSCRFCFTCISDYLDKNEICPGNTEDCKQEVLYLNENIYVDQPMNIKISKLQVKCKEMSCDYVDELRKMEEHSRACKYRSVACPYSNIGCDKCNISQDKVTDHLQSEIFAHTKLLMDFVVNFHNEMEMLKANNNGLSAVNELLRNEINELKLDGERRREEIAELQMKCADQAEEIELLNEDIPALRNVDRNVSDRLDGLQLIIEGNQVAMRAVENDFQQQIAQCATNCQQAEIKQKELIDKIGQMENKQKVDLTEMSNKIDKSSGNVDRKLLEMAANQNQRINGEFMWKLDKFTDKMADAKKGINAIIYSESFLTHKNGFKMCLRVDPDGDGVGKGTHLSVFFCLMKGEFDGILEWPFSH 404
BLAST of TNF receptor-associated factor vs. Planmine SMEST
Match: SMESG000025901.1 (SMESG000025901.1) HSP 1 Score: 793.497 bits (2048), Expect = 0.000e+0 Identity = 417/513 (81.29%), Postives = 425/513 (82.85%), Query Frame = 1
Query: 103 MSGSKLENVGQIMRDYNYESVTEIQNDMLCLLCKKLLVNARCAPCSCRFCFTCISDYLDKNEICPGNTEDCKQELLHLNENIYVDQPMNIKISKLQVKCKEMSCDYVDELRKMEEHSRTCKYRSVACPYSNIGCDKCNISQDKVTDHLQSEIFAHTKLLMDFVVNFNNEMEMLKANNNGLSAVNELLRNEINELKLDGERRREEIAE-----------------------------------LQRKCADQAEEIELLNEDIPALRNVDRNVSDRLDGLQLIIEGNQVAMRAVENDFQQQIAQCATNCQQAEIKQKELIDKIGQMENKQKVDLTEMSNKIDKLSGNVDRKLLEMAANQNQLNYGEFVWKLDKFTDKMADAKNGINAIIYSESFLTHKNGFKMCLRVDPDGFGDGKGTHLSVFFCLMKGEFDGILEWPFRHSVTFALINQRTRLPHVSRTAKCADYTNNKELIQSTDRNNGFGFDQFLSLKELSSNPDLMRNNQIFIKCSVDIDS 1536
MS SKLENV QIMRDYNYESVTEIQNDMLCLLCKKLLVNARCAPCSCRFCFTCISDYLDKNEICPGNTEDCKQE+LHLNENIYVDQPMNIKISKLQVKCKEMSCDYVDELRKMEEHSRTCKYRS AC YSNIGCDKCNISQDKV DHLQSEIF HTKLLMDFVVNFNNEMEMLKANNNGLSAVNELLRNEINELKLDGERRREEIAE LQRKCADQAEEIELLNEDIPALRNVDRNVSDRLDGLQLIIEGN QKELIDKIGQMENKQKVDLTEMSNKIDKLSGNVDRKLLEMAANQNQ GEFVWKLDKFTDKMADAKNGINAIIYSESFLTHKNGFKMCL V PDG G GKGTHLSV+F LMKGEFDGILEWPFRHSVT ALINQRTRLPHVS T K A+ +N+K LIQ TDRN G GF +F+S +ELSSNPDLMRNNQIFIKCSVDIDS
Sbjct: 1 MSCSKLENVWQIMRDYNYESVTEIQNDMLCLLCKKLLVNARCAPCSCRFCFTCISDYLDKNEICPGNTEDCKQEVLHLNENIYVDQPMNIKISKLQVKCKEMSCDYVDELRKMEEHSRTCKYRSEACLYSNIGCDKCNISQDKVEDHLQSEIFVHTKLLMDFVVNFNNEMEMLKANNNGLSAVNELLRNEINELKLDGERRREEIAELRVNIICLNGENAAMRENMDKLISAGERNQVEIGDLQRKCADQAEEIELLNEDIPALRNVDRNVSDRLDGLQLIIEGN----------------------------QKELIDKIGQMENKQKVDLTEMSNKIDKLSGNVDRKLLEMAANQNQRINGEFVWKLDKFTDKMADAKNGINAIIYSESFLTHKNGFKMCLSVYPDGVGVGKGTHLSVYFHLMKGEFDGILEWPFRHSVTLALINQRTRLPHVSETTKYANDSNSKTLIQPTDRNAGLGFPKFVSHEELSSNPDLMRNNQIFIKCSVDIDS 485
BLAST of TNF receptor-associated factor vs. Planmine SMEST
Match: SMESG000025998.1 (SMESG000025998.1) HSP 1 Score: 792.341 bits (2045), Expect = 0.000e+0 Identity = 406/479 (84.76%), Postives = 425/479 (88.73%), Query Frame = 1
Query: 103 MSGSKLENVGQIMRDYNYESVTEIQNDMLCLLCKKLLVNARCAPCSCRFCFTCISDYLD-KNEICPGNTEDCKQELLHLNENIYVDQPMNIKISKLQVKCKEMSCDYVDELRKMEEHSRTCKYRSVACPYSNIGCDKCNISQDKVTDHLQSEIFAHTKLLMDFVVNFNNEMEMLKANNNGLSAVNELLRNEINELKLDGERRREEIAELQRKCADQAEEIELLNEDIPALRNVDRNVSDRLDGLQLIIEGNQVAMRAVENDFQQQIAQCATNCQQAEIKQKELIDKIGQMENKQKVDLTEMSNKIDKLSGNVDRKLLEMAANQNQLNYGEFVWKLDKFTDKMADAKNGINAIIYSESFLTHKNGFKMCLRVDPDGFGDGKGTHLSVFFCLMKGEFDGILEWPFRHSVTFALINQRTRLPHVSRTAKCADYTNNKELIQSTDRNNGFGFDQFLSLKELSSNPDLMRNNQIFIKCSVDIDS 1536
MSGSKLENVGQIMRDYNYESVTEIQNDMLCLLCKKLLVNARCAPCSCRFCFTCISD+LD K + CPGNTE+CKQE+LHLNENI VD PMN+KI+KLQVKCKE SCDYVDELRKME+HS+TCKYRSVACPYSNIGC+KCNISQDKV DHL SEI AHTKLLMDFVVNF+NEMEMLKANNNGLSAVNELLRNEINELKLDGERRREEIAELQ+KCADQAEEIELLNEDIPALRNVDRNVSDRLDGLQLIIEGN QKELIDKIGQMENKQKVDLTEMSNKIDKLSGNVDRKLLEMAANQNQ GEFVWKLDKFTDKMADAKNG NAIIYSESFLTHKNG+KMCL VDPDG G GKGTHLSVFFCLMKGEFDGILEWPF HSVTFALINQRTRLPHVS TAK +DY NNK IQ TDRN G+G+ +F+S +ELSSNPDLMRNN+IFIKCSVDIDS
Sbjct: 1 MSGSKLENVGQIMRDYNYESVTEIQNDMLCLLCKKLLVNARCAPCSCRFCFTCISDFLDHKKKNCPGNTEECKQEMLHLNENICVDYPMNMKIAKLQVKCKEKSCDYVDELRKMEDHSQTCKYRSVACPYSNIGCNKCNISQDKVADHLLSEILAHTKLLMDFVVNFHNEMEMLKANNNGLSAVNELLRNEINELKLDGERRREEIAELQKKCADQAEEIELLNEDIPALRNVDRNVSDRLDGLQLIIEGN----------------------------QKELIDKIGQMENKQKVDLTEMSNKIDKLSGNVDRKLLEMAANQNQRINGEFVWKLDKFTDKMADAKNGTNAIIYSESFLTHKNGYKMCLLVDPDGNGGGKGTHLSVFFCLMKGEFDGILEWPFGHSVTFALINQRTRLPHVSGTAKRSDYINNKAFIQPTDRNAGWGYAKFVSHEELSSNPDLMRNNEIFIKCSVDIDS 451 The following BLAST results are available for this feature:
BLAST of TNF receptor-associated factor vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of TNF receptor-associated factor vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 2
BLAST of TNF receptor-associated factor vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of TNF receptor-associated factor vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of TNF receptor-associated factor vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of TNF receptor-associated factor vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of TNF receptor-associated factor vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of TNF receptor-associated factor vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of TNF receptor-associated factor vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of TNF receptor-associated factor vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of TNF receptor-associated factor vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of TNF receptor-associated factor vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of TNF receptor-associated factor vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of TNF receptor-associated factor vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30017619 ID=SMED30017619|Name=TNF receptor-associated factor|organism=Schmidtea mediterranea sexual|type=transcript|length=1590bpback to top protein sequence of SMED30017619-orf-1 >SMED30017619-orf-1 ID=SMED30017619-orf-1|Name=SMED30017619-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=479bp MSGSKLENVGQIMRDYNYESVTEIQNDMLCLLCKKLLVNARCAPCSCRFCback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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