Parathyroid hormone receptor 1

Query:   34 FAMRLFVWILLTFIWCPFLQGKSIRKLEYKIEHDSQETLLRKAQENCNSKISNFSIAKLSLNTSFCRPVWDGVVCWYGYFQSGKTASQPCPHYIDKFIRKGKVYKRCTVNGEWFRRANSTKPWTDFGECKQ------STNKEPALFFVVTISNIGFFISITSVLLGIFILRFFKNLHCDRNTIHINLFVACLLRSCF---------------SLFSQLQTNNETNTF------------CKVFMSMHNYLIMANFTWVFVEALYLHNVLTLHTFKETSGVVFLYILVGWGXXXXXXXXXXXXXXVFDNTYCWD--AGDSQITLDMWVLFVYPVLLLIQ-NIIFFIKLIVILHAKM-----VTHQLTASQNKFRKLARSILVLMVVFGIYQLIFVPLDLIENMHN-NKVTFQIKMCAEHLINSAQGFLLAMMFCFCNSEVLKEIKR 1242
                L VW  L    C  L  ++    +  I  + Q  L+ KA+  C   I+    A+L      C P WDG++CW      GK ++ PCP YI  F  KG  ++ C  NG W    +  K W ++ +C +      S  K+     +  +  +G+ IS  S+ + I I+ +F+ LHC RN IH++LFV+ +LR+                  L S +  ++  N+             CK+ + M  Y +  N+ W+ VE LYLHN++ +  F +T   ++ +IL+GWG P   +  W + R    +  CW+  AGD +     W+ +  P+L  I  N I F+  + +L  K+     V H    ++ ++RKLA+S LVL++VFG++ ++FV L      H+   + ++I+M  E   NS QGF +++++C+CN EV  E+K+
Sbjct:    4 LGASLHVWGWLMLGSC--LLARAQLDSDGTITIEEQIVLVLKAKVQCELNIT----AQLQEGEGNCFPEWDGLICW-PRGTVGKISAVPCPPYIYDFNHKGVAFRHCNPNGTWDFMHSLNKTWANYSDCLRFLQPDISIGKQEFFERLYVMYTVGYSISFGSLAVAILIIGYFRRLHCTRNYIHMHLFVSFMLRATSIFVKDRVVHAHIGVKELESLIMQDDPQNSIEATSVDKSQYIGCKIAVVMFIYFLATNYYWILVEGLYLHNLIFVAFFSDTK-YLWGFILIGWGFPAAFVAAWAVARATLADARCWELSAGDIK-----WI-YQAPILAAIGLNFILFLNTVRVLATKIWETNAVGHD---TRKQYRKLAKSTLVLVLVFGVHYIVFVCLP-----HSFTGLGWEIRMHCELFFNSFQGFFVSIIYCYCNGEVQAEVKK 426          

Query:  229 CRPVWDGVVCWYGYFQSGKTASQPCPHYIDKFIRKGKVYKRCTVNGEWFRRANSTKPWTDFGECKQ----STNKEPALFFVVTISNIGFFISITSVLLGIFILRFFKNLHCDRNTIHINLFVACLLRSCFSLF--------------SQLQTNNETNTF----------------CKVFMSMHNYLIMANFTWVFVEALYLHNVLTLHTFKETSGVVFLYILVGWGXXXXXXXXXXXXXXVFDNTYCWDAGDSQITLDMWVLFVYPVLLLIQNIIFFIKLIVILHAKM--VTHQLTASQNKFRKLARSILVLMVVFGIYQLIFVPLDLIENMHNNKVTFQIKMCAEHLINSAQGFLLAMMFCFCNSEVLKEIKRKF 1248
            C P WD ++CW      G+  + PCP YI  F  KG  Y+RC  NG W       + W ++ EC +     T +      +  I  +G+ +S+ S+ + + IL +F+ LHC RN IH++LF++ +LR+  S+F              ++  T  E                    C+V ++   Y +  N+ W+ VE LYLH+++ +  F E    ++ + + GWGLP + + +W+ +R    NT CWD          W++ V  +  ++ N I FI ++ +L  K+         ++ ++RKL +S LVLM +FG++ ++F+     E    +   +Q++M  E L NS QGF +A+++CFCN EV  EIK+ +
Sbjct:  108 CLPEWDHILCW-PLGAPGEVVAVPCPDYIYDFNHKGHAYRRCDRNGSWELVPGHNRTWANYSECVKFLTNETREREVFDRLGMIYTVGYSVSLASLTVAVLILAYFRRLHCTRNYIHMHLFLSFMLRAV-SIFVKDAVLYSGATLDEAERLTEEELRAIAQAPPPPATAAAGYAGCRVAVTFFLYFLATNYYWILVEGLYLHSLIFMAFFSEKK-YLWGFTVFGWGLPAVFVAVWVSVRATLANTGCWDLSSGN---KKWIIQVPILASIVLNFILFINIVRVLATKLRETNAGRCDTRQQYRKLLKSTLVLMPLFGVHYIVFMATPYTEV---SGTLWQVQMHYEMLFNSFQGFFVAIIYCFCNGEVQAEIKKSW 474          

Query:  229 CRPVWDGVVCWYGYFQSGKTASQPCPHYIDKFIRKGKVYKRCTVNGEWFRRANSTKPWTDFGEC----KQSTNKEPALFFVVTISNIGFFISITSVLLGIFILRFFKNLHCDRNTIHINLFVACLLRSCFSLF--------------SQLQTNNETNTF----------------CKVFMSMHNYLIMANFTWVFVEALYLHNVLTLHTFKETSGVVFLYILVGWGXXXXXXXXXXXXXXVFDNTYCWDAGDSQITLDMWVLFVYPVLLLIQNIIFFIKLIVILHAKM--VTHQLTASQNKFRKLARSILVLMVVFGIYQLIFVPLDLIENMHNNKVTFQIKMCAEHLINSAQGFLLAMMFCFCNSEVLKEIKRKF 1248
            C P WD ++CW      G+  + PCP YI  F  KG  Y+RC  NG W       + W ++ EC       T +      +  I  +G+ +S+ S+ + + IL +F+ LHC RN IH++LF++ +LR+  S+F              ++  T  E                    C+V ++   Y +  N+ W+ VE LYLH+++ +  F E    ++ + + GWGLP + + +W+ +R    NT CWD          W++ V  +  ++ N I FI ++ +L  K+         ++ ++RKL +S LVLM +FG++ ++F+     E    +   +Q++M  E L NS QGF +A+++CFCN EV  EIK+ +
Sbjct:  108 CLPEWDHILCW-PLGAPGEVVAVPCPDYIYDFNHKGHAYRRCDRNGSWELVPGHNRTWANYSECVKFLTNETREREVFDRLGMIYTVGYSVSLASLTVAVLILAYFRRLHCTRNYIHMHLFLSFMLRAV-SIFVKDAVLYSGATLDEAERLTEEELRAIAQAPPPPATAAAGYAGCRVAVTFFLYFLATNYYWILVEGLYLHSLIFMAFFSEKK-YLWGFTVFGWGLPAVFVAVWVSVRATLANTGCWDLSSGN---KKWIIQVPILASIVLNFILFINIVRVLATKLRETNAGRCDTRQQYRKLLKSTLVLMPLFGVHYIVFMATPYTEV---SGTLWQVQMHYEMLFNSFQGFFVAIIYCFCNGEVQAEIKKSW 474          

Query:  229 CRPVWDGVVCWYGYFQSGKTASQPCPHYIDKFIRKGKVYKRCTVNGEWFRRANSTKPWTDFGEC----KQSTNKEPALFFVVTISNIGFFISITSVLLGIFILRFFKNLHCDRNTIHINLFVACLLRSCFSLF--------------SQLQTNNETNTF----------------CKVFMSMHNYLIMANFTWVFVEALYLHNVLTLHTFKETSGVVFLYILVGWGXXXXXXXXXXXXXXVFDNTYCWDAGDSQITLDMWVLFVYPVLLLIQNIIFFIKLIVILHAKM--VTHQLTASQNKFRKLARSILVLMVVFGIYQLIFVPLDLIENMHNNKVTFQIKMCAEHLINSAQGFLLAMMFCFCNSEVLKEIKRKF 1248
            C P WD ++CW      G+  + PCP YI  F  KG  Y+RC  NG W       + W ++ EC       T +      +  I  +G+ +S+ S+ + + IL +F+ LHC RN IH++LF++ +LR+  S+F              ++  T  E                    C+V ++   Y +  N+ W+ VE LYLH+++ +  F E    ++ + + GWGLP + + +W+ +R    NT CWD          W++ V  +  ++ N I FI ++ +L  K+         ++ ++RKL +S LVLM +FG++ ++F+     E    +   +Q++M  E L NS QGF +A+++CFCN EV  EIK+ +
Sbjct:  108 CLPEWDHILCW-PLGAPGEVVAVPCPDYIYDFNHKGHAYRRCDRNGSWELVPGHNRTWANYSECVKFLTNETREREVFDRLGMIYTVGYSVSLASLTVAVLILAYFRRLHCTRNYIHMHLFLSFMLRAV-SIFVKDAVLYSGATLDEAERLTEEELRAIAQAPPPPATAAAGYAGCRVAVTFFLYFLATNYYWILVEGLYLHSLIFMAFFSEKK-YLWGFTVFGWGLPAVFVAVWVSVRATLANTGCWDLSSGN---KKWIIQVPILASIVLNFILFINIVRVLATKLRETNAGRCDTRQQYRKLLKSTLVLMPLFGVHYIVFMATPYTEV---SGTLWQVQMHYEMLFNSFQGFFVAIIYCFCNGEVQAEIKKSW 474          

Query:  229 CRPVWDGVVCWYGYFQSGKTASQPCPHYIDKFIRKGKVYKRCTVNGEWFRRANSTKPWTDFGEC----KQSTNKEPALFFVVTISNIGFFISITSVLLGIFILRFFKNLHCDRNTIHINLFVACLLRSCFSLF--------------SQLQTNNETNTF----------------CKVFMSMHNYLIMANFTWVFVEALYLHNVLTLHTFKETSGVVFLYILVGWGXXXXXXXXXXXXXXVFDNTYCWDAGDSQITLDMWVLFVYPVLLLIQNIIFFIKLIVILHAKM--VTHQLTASQNKFRKLARSILVLMVVFGIYQLIFVPLDLIENMHNNKVTFQIKMCAEHLINSAQGFLLAMMFCFCNSEVLKEIKRKF 1248
            C P WD ++CW      G+  + PCP YI  F  KG  Y+RC  NG W       + W ++ EC       T +      +  I  +G+ +S+ S+ + + IL +F+ LHC RN IH++LF++ +LR+  S+F              ++  T  E                    C+V ++   Y +  N+ W+ VE LYLH+++ +  F E    ++ + + GWGLP + + +W+ +R    NT CWD          W++ V  +  ++ N I FI ++ +L  K+         ++ ++RKL +S LVLM +FG++ ++F+     E    +   +Q++M  E L NS QGF +A+++CFCN EV  EIK+ +
Sbjct:  108 CLPEWDHILCW-PLGAPGEVVAVPCPDYIYDFNHKGHAYRRCDRNGSWELVPGHNRTWANYSECVKFLTNETREREVFDRLGMIYTVGYSVSLASLTVAVLILAYFRRLHCTRNYIHMHLFLSFMLRAV-SIFVKDAVLYSGATLDEAERLTEEELRAIAQAPPPPATAAAGYAGCRVAVTFFLYFLATNYYWILVEGLYLHSLIFMAFFSEKK-YLWGFTVFGWGLPAVFVAVWVSVRATLANTGCWDLSSGN---KKWIIQVPILASIVLNFILFINIVRVLATKLRETNAGRCDTRQQYRKLLKSTLVLMPLFGVHYIVFMATPYTEV---SGTLWQVQMHYEMLFNSFQGFFVAIIYCFCNGEVQAEIKKSW 474          

Query:  211 SLNTSFCRPVWDGVVCWYGYFQSGKTASQPCPHYI-------DKFIRKGKVYKRCTVNGEWFRRANST---KPWTDFGECKQSTNKE-PALF--FVVTISNIGFFISITSVLLGIFILRFFKNLHCDRNTIHINLFVACLLR-SCFSLFSQLQTNN--------------ETNTFCKVFMSMHNYLIMANFTWVFVEALYLHNVLTLHTFKETSGVVFLYILVGWGXXXXXXXXXXXXXXVFD----NTYCWDAGDSQITLDMWVLFVYPVLLLIQNIIFFIKLIVILHAKMVTHQLTASQNKFRKLARSILVLMVVFGIYQLIFVPLDLIENMHNNKVTFQIKMCAEHLINSAQGFLLAMMFCFCNSEVLKEIKRKF 1248
            S N   C   +D  +CW      G+  ++ CP          ++   +  V + C   G W + +N T   K   ++ +C Q   +  P +    V+++S    F+S+  ++  I +   F ++ C R +IH NL  A + R +  ++++ +QT N              +    CK  +    Y  +A+  W+ +E  +L++  T+   + +     LY+  GWG+P + +  W ++         N++CW        L +W+L       LI N+IF + ++VIL  K+ T     S+  +R + ++ L+L+ + GI     +PL   E  H + V     M    ++  +QG  +A+++CF NSE+   +KR+ 
Sbjct:   22 SYNPGGCSVDFDKSLCW-ASAHIGQQMTRDCPFTFCTAIPGCEEIKDRYMVSRNCNSMGVW-QDSNYTMCIKVVEEYAQCLQGFCRVCPDVLRDLVISVSLTLSFVSVILLVAAIVLFSIFDSIQCRRLSIHKNLATAFVFRFAVLAIWTIVQTTNVFQDCTRLTPLPLWDYEWICKAILWFVIYFNVASVMWMLIEGAFLYSRFTVFAMRHSDAPWSLYLACGWGVPFVVVTAWALVHQYISSQQTNSFCWLPYAQ--GLHLWILAGTMGSALIMNLIFLLMIVVILVQKLRTENSAESKKIWRTI-KATLLLVPLLGISN---IPL-FYEPEHPSSV----YMLGSAILQHSQGIFIAVLYCFLNSEIQGALKRQL 386          

Query:  214 LNTSFCRPVWDGVVCWYGYFQSGKTAS--QPCPHYIDKFIRKGKVYKR-----CTVNGEWFRRANST-KPWTDFGECKQSTNKEPALFFVVTISNIGFFISITSVLLGIFILRFFKNLHCDRNTI-HINLFVACLLRSCFSLF--SQLQTNN--------ETNTFCKVFMSMH-NYLIMANFTWVFVEALYLHNVLTLHTFKETSGVVFL-YILVGWGXXXXXXXXXXXXXXVFDNT-YCWDAGDSQITLDMWVLFVYPVLLLIQNIIFFIKLIVILHAKMVTHQLTASQNKFRKLARSILVLMVVFGIYQLIFVPLDLIENMHNNKVTFQIKMCAEHLINSAQGFLLAMMFCFCNSEVLKEIKRKFENHRNSRSL--QTTDEVKIRENSYRKRRGNRDSLKQTDHQV 1365
            ++ S C P WDG  C    F S       + CP+YI         Y R     C  NG      N+  +  TD+  C  + + E  +   +    + +  S+  ++  +F+L   + + C    I H +L ++CLL   F L   S    N+        + + FC++  S+   YL + NFTW+  EA+YL  +L  HT + + G     Y ++ WG+P +  +++I +R + D+   CW   +S +    W++ + P LL +   +  + LIV +  K +       + ++RK  R  L+L+ VFG+ QL+ +          +   +Q+    +  +N  QG  ++ + C+ N  V++ + + + +H+  R+L  +    + I+E+     R       QT+H V
Sbjct:  141 VDDSPCPPTWDGWNC----FDSATPGVVFKQCPNYIYGGSNIKTDYDRLSQKVCRSNGWATPEVNAAAREHTDYTGCMSNGDVEARILAGL----LTYSASVIFLIPAVFLLTLLRPIRCQPMFILHRHLLISCLLYGAFYLITVSLFVVNDAPLSSQVFQNHLFCRLLFSIQLRYLRLTNFTWMLAEAVYLWRLL--HTAQHSEGETLRSYKVICWGVPGVITVVYIFVRSLNDDVGMCW-IENSTVAWIEWMI-ITPSLLAMGVNLLLLGLIVYILVKKLRCDPHLERIQYRKAVRGALMLIPVFGVQQLLTI-------YRFSNTYYQV---TDQSLNGLQGMFVSFIVCYTNRSVVECVLKFWSSHQEKRALGAECRQRMSIQESGKLILRP-----PQTEHVV 521          

Query:  226 FCRPVWDGVVCWYGYFQSGKTASQPCPHYIDKFIRKGKVYKRCTVNGEWF-RRANSTKP----WTDFGEC--------KQSTNKEPALFFVVTISN------IGFFISITSVLLGIFILRFFKNLHCDRNTIHINLFVACLLRSCFSLF-----------------SQLQTNNETNTFCKVFMSMHNYLIMANFTWVFVEALYLHNVLTLHTFKETSGVVFLYILVGWGXXXXXXXXXXXXXXV---FDNTYCWDAGDSQITLDMWVLFVYPVLLLIQNIIFFIKLIVILHAKMVTHQLTASQNKFRKLARSILVLMVVFGIYQLI----FVPLDLIENMHNNKVTFQIKMCAEHLINSAQGFLLAMMFCFCNSEVLKEIKRKFENHR 1260
            +C   +D V+CW     +     Q CPH +        + K C V+G W  R A    P    WT+F  C         Q+ N E          N      +G  +S+ S++L I I  +F+ L   RN +H++L +A L+     L                  ++ +T N     C+       Y     F W+F+E +YL+N +    F  +   +  Y + G+G+PL+  ++W+++ L+   F    C   G   +  + W+L    +  L+ N+ F   +I +L++K V      S+   +K  ++ ++L+ + G+  ++    F P        +N + F +           QG ++A ++CF N EV   +K  +  +R
Sbjct:   73 WCNATYDTVLCWPPTPANSSVTLQ-CPH-MKGLDPNKNITKDCHVSGVWSGRNAGEMGPTLPGWTNFTMCYTDEVIYIMQNLNNESLTIAQEVARNARKLEFVGLGLSLVSLILAISIFSYFRRLRVFRNLLHLHLMIAMLMVVILRLVLYIDLIFTGENGPHTNSAEGKTINTMPIVCEGMFFFLEYFKTVTFCWMFLEGIYLNNQIVFGFFN-SEPKLLPYFIAGYGIPLVHTMLWLLVVLIKKDFKVERCL--GSYYLEPEFWILDGPRMAELVINLFFICNVIRVLYSK-VRESNNTSEAGLKKSVKAAMMLLPLLGVPNIMQTIPFAP------TRDNIMVFAVWTYTASFTYMYQGLMVASIYCFTNKEVNHVLKTFYARYR 448          

Query:  226 FCRPVWDGVVCWYGYFQSGKTASQPCPHYIDKFIRKGKVYKRCTVNGEWF-RRANSTKP----WTDFGEC--------KQSTNKEPALFFVVTISN------IGFFISITSVLLGIFILRFFKNLHCDRNTIHINLFVACLLRSCFSLF-----------------SQLQTNNETNTFCKVFMSMHNYLIMANFTWVFVEALYLHNVLTLHTFKETSGVVFLYILVGWGXXXXXXXXXXXXXXV---FDNTYCWDAGDSQITLDMWVLFVYPVLLLIQNIIFFIKLIVILHAKMVTHQLTASQNKFRKLARSILVLMVVFGIYQLI----FVPLDLIENMHNNKVTFQIKMCAEHLINSAQGFLLAMMFCFCNSEVLKEIKRKFENHR 1260
            +C   +D V+CW     +     Q CPH +        + K C V+G W  R A    P    WT+F  C         Q+ N E          N      +G  +S+ S++L I I  +F+ L   RN +H++L +A L+     L                  ++ +T N     C+       Y     F W+F+E +YL+N +    F  +   +  Y + G+G+PL+  ++W+++ L+   F    C   G   +  + W+L    +  L+ N+ F   +I +L++K V      S+   +K  ++ ++L+ + G+  ++    F P        +N + F +           QG ++A ++CF N EV   +K  +  +R
Sbjct:   73 WCNATYDTVLCWPPTPANSSVTLQ-CPH-MKGLDPNKNITKDCHVSGVWSGRNAGEMGPTLPGWTNFTMCYTDEVIYIMQNLNNESLTIAQEVARNARKLEFVGLGLSLVSLILAISIFSYFRRLRVFRNLLHLHLMIAMLMVVILRLVLYIDLIFTGENGPHTNSAEGKTINTMPIVCEGMFFFLEYFKTVTFCWMFLEGIYLNNQIVFGFFN-SEPKLLPYFIAGYGIPLVHTMLWLLVVLIKKDFKVERCL--GSYYLEPEFWILDGPRMAELVINLFFICNVIRVLYSK-VRESNNTSEAGLKKSVKAAMMLLPLLGVPNIMQTIPFAP------TRDNIMVFAVWTYTASFTYMYQGLMVASIYCFTNKEVNHVLKTFYARYR 448          

Query:  226 FCRPVWDGVVCWYGYFQSGKTASQPCPHYIDKFIRKGKVYKRCTVNGEWF-RRANSTKP----WTDFGEC--------KQSTNKEPALFFVVTISN------IGFFISITSVLLGIFILRFFKNLHCDRNTIHINLFVACLLRSCFSLF-----------------SQLQTNNETNTFCKVFMSMHNYLIMANFTWVFVEALYLHNVLTLHTFKETSGVVFLYILVGWGXXXXXXXXXXXXXXV---FDNTYCWDAGDSQITLDMWVLFVYPVLLLIQNIIFFIKLIVILHAKMVTHQLTASQNKFRKLARSILVLMVVFGIYQLI----FVPLDLIENMHNNKVTFQIKMCAEHLINSAQGFLLAMMFCFCNSEVLKEIKRKFENHR 1260
            +C   +D V+CW     +     Q CPH +        + K C V+G W  R A    P    WT+F  C         Q+ N E          N      +G  +S+ S++L I I  +F+ L   RN +H++L +A L+     L                  ++ +T N     C+       Y     F W+F+E +YL+N +    F  +   +  Y + G+G+PL+  ++W+++ L+   F    C   G   +  + W+L    +  L+ N+ F   +I +L++K V      S+   +K  ++ ++L+ + G+  ++    F P        +N + F +           QG ++A ++CF N EV   +K  +  +R
Sbjct:   73 WCNATYDTVLCWPPTPANSSVTLQ-CPH-MKGLDPNKNITKDCHVSGVWSGRNAGEMGPTLPGWTNFTMCYTDEVIYIMQNLNNESLTIAQEVARNARKLEFVGLGLSLVSLILAISIFSYFRRLRVFRNLLHLHLMIAMLMVVILRLVLYIDLIFTGENGPHTNSAEGKTINTMPIVCEGMFFFLEYFKTVTFCWMFLEGIYLNNQIVFGFFN-SEPKLLPYFIAGYGIPLVHTMLWLLVVLIKKDFKVERCL--GSYYLEPEFWILDGPRMAELVINLFFICNVIRVLYSK-VRESNNTSEAGLKKSVKAAMMLLPLLGVPNIMQTIPFAP------TRDNIMVFAVWTYTASFTYMYQGLMVASIYCFTNKEVNHVLKTFYARYR 448          

Query:  229 CRPVWDGVVCWYGYFQSGKTASQPCPHYIDKFIRKGKVYKRCTVNGEWFRRANST-KPWTDFGECKQSTNK-------EPALFFVVTISNIGFFISITSVLLGIFILRFFKNLHCDRNTIHINLFVACLLRS---CFSLFSQLQTNNETNTFCKVFMSMHNYLIMANFTWVFVEALYLHNVLTLHTFKETSGVVFLYILVGWGXXXXXXXXXXXXXXV---FDNTY-------CWDAGDSQITLDMWVLFVYPVLLLIQNIIFFIKLIVILHAKMVTHQLTASQNKFRKLARSILVLMVVFGIYQLIFVPLDLIENMHNNKVTFQIKMCAEHLINSAQGFLLAMMFCFCNSEVLKEIKRKFENHRNSRSLQTTDEVKIRENSYRKR---RGNRDSLKQT 1353
            C   +D V+CW     +G  A  PC    ++F  KG V+   T N   F   N T   ++D+  C Q++          P +     I   G+F+S  ++++ + I   FK+L C RNTIH NLF+  +  +     +LF Q+ T   +   C   + M  Y  + NF W+FVE LYL+  L + TF   +    +Y L+GWG P + I++W I +      +N +       C    +S I    W+  V   L L+ N++F I+++ +L  K+ +   T    ++ K ++++LVL+ +FGI  L      L+       ++  +       + S QGF +A+ +CF NSEV + ++  F   R SR++     +K R +   K    R   +SL+ T
Sbjct:   84 CPSSFDSVLCW-PRTNAGSLAVLPC---FEEF--KG-VHYDTTDNATRFCFPNGTWDHYSDYDRCHQNSGSIPVVPDFSPNVELPAIIYAGGYFLSFATLVVALIIFLSFKDLRCLRNTIHANLFLTYITSALLWILTLFLQVITTESSQAGCITLVIMFQYFYLTNFFWMFVEGLYLYT-LVVQTFSSDNISFIIYALIGWGCPAVCILVWSIAKAFAPHLENEHFNGLEIDCAWMRESHID---WIFKVPASLALLVNLVFLIRIMWVLITKLRSAH-TLETRQYYKASKALLVLIPLFGITYL------LVLTGPEQGISRNLFEAIRAFLISTQGFFVALFYCFLNSEVRQTLRHGFTRWRESRNIHRNSSIKNRRHRASKDYSLRSRTESLRLT 464          

Query:  229 CRPVWDGVVCWYGYFQSGKTASQPCPHYIDKFIRKGKVYKRCTVNGEWFRRANST-KPWTDFGECKQSTNK-------EPALFFVVTISNIGFFISITSVLLGIFILRFFKNLHCDRNTIHINLFVACLLRS---CFSLFSQLQTNNETNTFCKVFMSMHNYLIMANFTWVFVEALYLHNVLTLHTFKETSGVVFLYILVGWGXXXXXXXXXXXXXXV---FDNTY-------CWDAGDSQITLDMWVLFVYPVLLLIQNIIFFIKLIVILHAKMVTHQLTASQNKFRKLARSILVLMVVFGIYQLIFVPLDLIENMHNNKVTFQIKMCAEHLINSAQGFLLAMMFCFCNSEVLKEIKRKFENHRNSRSLQTTDEVKIREN 1308
            C   +D V+CW     +G  A  PC    ++F  KG V+   T N   F   N T   ++D+  C Q++          P +     I   G+F+S  ++++ + I   FK+L C RNTIH NLF+  +  +     +LF Q+ T   +   C   + M  Y  + NF W+FVE LYL+  L + TF   +    +Y L+GWG P + I++W I +      +N +       C    +S I    W+  V   L L+ N++F I+++ +L  K+ +   T    ++ K ++++LVL+ +FGI  L      L+       ++  +       + S QGF +A+ +CF NSEV + ++  F   R SR++     +K R  
Sbjct:   84 CPSSFDSVLCW-PRTNAGSLAVLPC---FEEF--KG-VHYDTTDNATRFCFPNGTWDHYSDYDRCHQNSGSIPVVPDFSPNVELPAIIYAGGYFLSFATLVVALIIFLSFKDLRCLRNTIHANLFLTYITSALLWILTLFLQVITTESSQAGCITLVIMFQYFYLTNFFWMFVEGLYLYT-LVVQTFSSDNISFIIYALIGWGCPAVCILVWSIAKAFAPHLENEHFNGLEIDCAWMRESHID---WIFKVPASLALLVNLVFLIRIMWVLITKLRSAH-TLETRQYYKASKALLVLIPLFGITYL------LVLTGPEQGISRNLFEAIRAFLISTQGFFVALFYCFLNSEVRQTLRHGFTRWRESRNIHRNSSIKNRST 446          

Query:  166 ENCNSKISNFSIAKLSLNTSFCRPVWDGVVCWYGYFQSGKTASQPCPHYIDKFIRKGKVYKRCTVNGEWFRRANSTK----PWTDFGEC---------KQSTNKEPALFFVV-----TISNIGFFISITSVLLGIFILRFFKNLHCDRNTIHINLFVACLLRSCFSL---FSQLQTNNE---TNT----------FCKVFMSMHNYLIMANFTWVFVEALYLHNVLTLHTFKETSGVVFLYILVGWGXXXXXXXXXXXXXXVFDNTYCWDA-GDSQITLDMWVLFVYPVLLLIQNIIFFIKLIVILHAKMVTHQLTASQNKFRKLARSILVLMVVFGIYQLI--FVPLDLIENMHNNKVTFQIKMCAEHLINSAQGFLLAMMFCFCNSEV 1224
            ENC++   N+++ +  L   +C   WD ++CW     +G  A   CP        +    ++C ++G W  R N+T+     WTD+G C         +Q  +K+   +  +     T+  +G  +S+ ++++ + I   F++L  +R  IH NLFVA +L+    L     Q +  N+   TNT           C+    +  Y   A F W+F+E LYLHN++T+  F+ +  + F   L GW +P++   +W    +++ +T   +   +  +T   W+L    + +++ N  F + +I +L  K+   Q  +   + RK  R+ +VL+ + GI  L+    PL    N       F +     H + S QGF +A+++CF N EV
Sbjct:  129 ENCSALFVNYTLPQTGL---YCNWTWDTLLCWPPT-PAGVLARMNCPGGFHGVDTRKFAIRKCELDGRWGSRPNATEVNPPGWTDYGPCYKPEIIRLMQQMGSKDFDAYIDIARRTRTLEIVGLCLSLFALIVSLLIFCTFRSLRNNRTKIHKNLFVAMVLQVIIRLTLYLDQFRRGNKEAATNTSLSVIENTPYLCEASYVLLEYARTAMFMWMFIEGLYLHNMVTVAVFQGSFPLKFFSRL-GWCVPILMTTVWARCTVMYMDTSLGECLWNYNLTPYYWILEGPRLAVILLNFCFLVNIIRVLVMKLRQSQ-ASDIEQTRKAVRAAIVLLPLLGITNLLHQLAPLKTATN-------FAVWSYGTHFLTSFQGFFIALIYCFLNGEV 505          

Query:  166 ENCNSKISNFSIAKLSLNTSFCRPVWDGVVCWYGYFQSGKTASQPCP---HYIDKFIRKGKVYKRCTVNGEWFRRANSTK----PWTDFGEC---------KQSTNKEPALFFVV-----TISNIGFFISITSVLLGIFILRFFKNLHCDRNTIHINLFVACLLRSCFSL---FSQLQTNNE---TNT----------FCKVFMSMHNYLIMANFTWVFVEALYLHNVLTLHTFKETSGVVFLYILVGWGXXXXXXXXXXXXXXVFDNTYCWDA-GDSQITLDMWVLFVYPVLLLIQNIIFFIKLIVILHAKMVTHQLTASQNKFRKLARSILVLMVVFGIYQLI--FVPLDLIENMHNNKVTFQIKMCAEHLINSAQGFLLAMMFCFCNSEV 1224
            ENC++   N+++ +  L   +C   WD ++CW     +G  A   CP   H +D   RK  + ++C ++G W  R N+T+     WTD+G C         +Q  +K+   +  +     T+  +G  +S+ ++++ + I   F++L  +R  IH NLFVA +L+    L     Q +  N+   TNT           C+    +  Y   A F W+F+E LYLHN++T+  F+ +  + F   L GW +P++   +W    +++ +T   +   +  +T   W+L    + +++ N  F + +I +L  K+   Q  +   + RK  R+ +VL+ + GI  L+    PL    N       F +     H + S QGF +A+++CF N EV
Sbjct:  129 ENCSALFVNYTLPQTGL---YCNWTWDTLLCWPPT-PAGVLARMNCPGGFHGVD--TRKFAI-RKCELDGRWGSRPNATEVNPPGWTDYGPCYKPEIIRLMQQMGSKDFDAYIDIARRTRTLEIVGLCLSLFALIVSLLIFCTFRSLRNNRTKIHKNLFVAMVLQVIIRLTLYLDQFRRGNKEAATNTSLSVIENTPYLCEASYVLLEYARTAMFMWMFIEGLYLHNMVTVAVFQGSFPLKFFSRL-GWCVPILMTTVWARCTVMYMDTSLGECLWNYNLTPYYWILEGPRLAVILLNFCFLVNIIRVLVMKLRQSQ-ASDIEQTRKAVRAAIVLLPLLGITNLLHQLAPLKTATN-------FAVWSYGTHFLTSFQGFFIALIYCFLNGEV 505          

Query:  166 ENCNSKISNFSIAKLSLNTSFCRPVWDGVVCWYGYFQSGKTASQPCP---HYIDKFIRKGKVYKRCTVNGEWFRRANSTK----PWTDFGEC---------KQSTNKEPALFFVV-----TISNIGFFISITSVLLGIFILRFFKNLHCDRNTIHINLFVACLLRSCFSL---FSQLQTNNE---TNT----------FCKVFMSMHNYLIMANFTWVFVEALYLHNVLTLHTFKETSGVVFLYILVGWGXXXXXXXXXXXXXXVFDNTYCWDA-GDSQITLDMWVLFVYPVLLLIQNIIFFIKLIVILHAKMVTHQLTASQNKFRKLARSILVLMVVFGIYQLI--FVPLDLIENMHNNKVTFQIKMCAEHLINSAQGFLLAMMFCFCNSEV 1224
            ENC++   N+++ +  L   +C   WD ++CW     +G  A   CP   H +D   RK  + ++C ++G W  R N+T+     WTD+G C         +Q  +K+   +  +     T+  +G  +S+ ++++ + I   F++L  +R  IH NLFVA +L+    L     Q +  N+   TNT           C+    +  Y   A F W+F+E LYLHN++T+  F+ +  + F   L GW +P++   +W    +++ +T   +   +  +T   W+L    + +++ N  F + +I +L  K+   Q  +   + RK  R+ +VL+ + GI  L+    PL    N       F +     H + S QGF +A+++CF N EV
Sbjct:  129 ENCSALFVNYTLPQTGL---YCNWTWDTLLCWPPT-PAGVLARMNCPGGFHGVD--TRKFAI-RKCELDGRWGSRPNATEVNPPGWTDYGPCYKPEIIRLMQQMGSKDFDAYIDIARRTRTLEIVGLCLSLFALIVSLLIFCTFRSLRNNRTKIHKNLFVAMVLQVIIRLTLYLDQFRRGNKEAATNTSLSVIENTPYLCEASYVLLEYARTAMFMWMFIEGLYLHNMVTVAVFQGSFPLKFFSRL-GWCVPILMTTVWARCTVMYMDTSLGECLWNYNLTPYYWILEGPRLAVILLNFCFLVNIIRVLVMKLRQSQ-ASDIEQTRKAVRAAIVLLPLLGITNLLHQLAPLKTATN-------FAVWSYGTHFLTSFQGFFIALIYCFLNGEV 505          

Query:  133 DSQETLLRKAQENCNSKISNFSIAKLSLNTSFCRPVWDGVVCWYGYFQSGKTASQPCPHYIDKFIRKGKVYKRCTVNGEWFRRANSTKPWTDFGECKQ-----STNKEPALF-FVVTISNIGFFISITSVLLGIFILRFFKNLHCDRNTIHINLFVACLLRSCFSLF---------SQLQ------------------TNNETNTFCKVFMSMHNYLIMANFTWVFVEALYLHNVLTLHTFKETSGVVFLYILVGWGXXXXXXXXXXXXXXVFDNTYCWDAGDSQITLDMWVLFVYPVLLLIQNIIFFIKLIVILHAKM--VTHQLTASQNKFRKLARSILVLMVVFGIYQLIFVPLDLIENMHNNKVTFQIKMCAEHLINSAQGFLLAMMFCFCNSEVLKEIKRKFENHRNSRSLQTTDEVKIRENS 1311
            + Q  LL  A+  C   I     +K   +   C P WDG++CW      GK  S  CP YI  F  KG  Y+RC +NG W   +++ K W ++ EC +     + N+E  +F  +  I  +G+ IS+ S+++   IL +F+ LHC RN IH++LF++ +LR+  S+F         S LQ                   N      CKV +++  Y +  N+ W+ VE LYLH+++ + TF      ++ + L+GWG+P + + IW  +R    +T CWD     +    W++ +  +  ++ N + F+ +I +L  K+         ++ ++RKL +S LVLM +FG++ ++F+ +   E    + V +QI+M  E L NS QGF +A+++CFCN EV  EIK+ +    N R+L    + K R  S
Sbjct:   10 EEQIYLLFNAKRKCERAIK----SKHKTSEGSCLPEWDGILCWPEGV-PGKMVSTSCPEYIYDFNHKGHAYRRCDLNGTWELASHNNKTWANYSECAKFFPHYNQNQEREVFDRLYLIYTVGYSISLGSLMVATVILGYFRRLHCTRNYIHMHLFLSFMLRA-ISIFVKDVVLYSGSALQEMERITVEDLKSITEAPPANKTQFIGCKVAVTLFLYFLATNYYWILVEGLYLHSLIFM-TFFSDRKYLWGFTLIGWGVPAMFVTIWASVRATLADTECWDLSAGNLK---WIVQIPILTAIVVNFLLFLNIIRVLATKLRETNAGRCDTRQQYRKLLKSTLVLMPLFGVHYIVFMAMPYTEV---SGVLWQIQMHYEMLFNSVQGFFVAIIYCFCNGEVQAEIKKAW----NRRTLALDFKRKARSGS 420          

Query:   46 LFVWILLTFIWCPFLQGKSIRKLEYKIEHDSQETLLRKAQENCNSKISNFSIAKLSLNTSFCRPVWDGVVCWYGYFQSGKTASQPCPHYIDKFIRKGKVYKRCTVNGEWFRRANSTKPWTDFGECKQ-----STNKEPALF-FVVTISNIGFFISITSVLLGIFILRFFKNLHCDRNTIHINLFVACLLRSCFSLF---------SQLQ------------------TNNETNTFCKVFMSMHNYLIMANFTWVFVEALYLHNVLTLHTFKETSGVVFLYILVGWGXXXXXXXXXXXXXXVFDNTYCWDAGDSQITLDMWVLFVYPVLLLIQNIIFFIKLIVILHAKM--VTHQLTASQNKFRKLARSILVLMVVFGIYQLIFVPLDLIENMHNNKVTFQIKMCAEHLINSAQGFLLAMMFCFCNSEVLKEIKRKFENHRNSRSLQTTDEVKIRENS 1311
            LF   LL+F++        +   +  +  + Q  LL  A+  C   I     +K   +   C P WDG++CW      GK  S  CP YI  F  KG  Y+RC +NG W   +++ K W ++ EC +     + N+E  +F  +  I  +G+ IS+ S+++   IL +F+ LHC RN IH++LF++ +LR+  S+F         S LQ                   N      CKV +++  Y +  N+ W+ VE LYLH+++ + TF      ++ + L+GWG+P + + IW  +R    +T CWD     +    W++ +  +  ++ N + F+ +I +L  K+         ++ ++RKL +S LVLM +FG++ ++F+ +   E    + V +QI+M  E L NS QGF +A+++CFCN EV  EIK+ +    N R+L    + K R  S
Sbjct:   13 LFCGTLLSFVY-------GLVDADDVLTKEEQIYLLFNAKRKCERAIK----SKHKTSEGSCLPEWDGILCWPEGV-PGKMVSTSCPEYIYDFNHKGHAYRRCDLNGTWELASHNNKTWANYSECAKFFPHYNQNQEREVFDRLYLIYTVGYSISLGSLMVATVILGYFRRLHCTRNYIHMHLFLSFMLRA-ISIFVKDVVLYSGSALQEMERITVEDLKSITEAPPANKTQFIGCKVAVTLFLYFLATNYYWILVEGLYLHSLIFM-TFFSDRKYLWGFTLIGWGVPAMFVTIWASVRATLADTECWDLSAGNLK---WIVQIPILTAIVVNFLLFLNIIRVLATKLRETNAGRCDTRQQYRKLLKSTLVLMPLFGVHYIVFMAMPYTEV---SGVLWQIQMHYEMLFNSVQGFFVAIIYCFCNGEVQAEIKKAW----NRRTLALDFKRKARSGS 445          

Query:  121 KIEHDSQETLLRKAQENCNSKISNFSIAKLSLNTSFCRPVWDGVVCWYGYFQSGKTASQPCPHYIDKFIRKGKVYKRCTVNGEWFRRANSTKPWTDFGECKQST--NKEPALFF--VVTISNIGFFISITSVLLGIFILRFFKNLHCDRNTIHINLFVACLLRSC--------------FSLFSQLQTNNETNTF------------CKVFMSMHNYLIMANFTWVFVEALYLHNVLTLHTFKETSGVVFLYILVGWGXXXXXXXXXXXXXXVFDNTYCWDAGDSQITLDMWVLFVYPVLLLIQ-NIIFFIKLIVILHAKM--VTHQLTASQNKFRKLARSILVLMVVFGIYQLIFVPLDLIENMHN-NKVTFQIKMCAEHLINSAQGFLLAMMFCFCNSEVLKEIKR 1242
            +I  + Q  +L  A+  C  K+S+   A        C P WDG++CW   F  G     PCP YI  F      Y+RC  NG W    +S K W ++ EC +S   NK+  +FF  +  +  +G+ +S +S+L+ IFI+ +F+ LHC RN IH++LFV+ +LR+                  F  +  NN TN              CKV + +  Y +  N+ W+ VE LYLH+++ +  F   S  ++ + L+GWG+P + +  W ++R    +  CW+     I    W+  V P+L  I  N I F+ ++ +L  K+         ++ ++RKLA+S LVL+ VFG++ ++FV +      H    + ++++M  E   NS QGF +++++C+CN EV  EIK+
Sbjct:   62 EITAEEQVQMLLDAKLQCLQKVSSDDPA-----VGVCVPEWDGLICWPQGF-PGTLTKTPCPGYIYDFNHAAHAYRRCDSNGSWVLAESSNKTWVNYTECIKSPEPNKKRQVFFERLHIMYTVGYAVSFSSLLVAIFIIGYFRRLHCTRNYIHMHLFVSFMLRAASIFVKDHVVHTSAGLQEFDAVLMNNFTNAVDVAPVDTSQYMGCKVTVLLFIYFLATNYYWILVEGLYLHSLIFM-AFLSDSKYLWGFTLIGWGVPAVFVAAWAVVRATLADARCWELSAGNIK---WIYQV-PILTAIGLNFILFVNIVRVLATKIRETNAGRYDTRKQYRKLAKSTLVLVFVFGVHYIVFVGMP-----HTFEGLGWEVRMYCELFFNSFQGFFVSIIYCYCNGEVQTEIKK 453          

Query:  121 KIEHDSQETLLRKAQENCNSKISNFSIAKLSLNTSFCRPVWDGVVCWYGYFQSGKTASQPCPHYIDKFIRKGKVYKRCTVNGEWFRRANSTKPWTDFGECKQST--NKEPALFF--VVTISNIGFFISITSVLLGIFILRFFKNLHCDRNTIHINLFVACLLRSC--------------FSLFSQLQTNNETNTF------------CKVFMSMHNYLIMANFTWVFVEALYLHNVLTLHTFKETSGVVFLYILVGWGXXXXXXXXXXXXXXVFDNTYCWDAGDSQITLDMWVLFVYPVLLLIQ-NIIFFIKLIVILHAKM--VTHQLTASQNKFRKLARSILVLMVVFGIYQLIFVPLDLIENMHN-NKVTFQIKMCAEHLINSAQGFLLAMMFCFCNSEVLKEIKR 1242
            +I  + Q  +L  A+  C  K+S+   A        C P WDG++CW   F  G     PCP YI  F      Y+RC  NG W    +S K W ++ EC +S   NK+  +FF  +  +  +G+ +S +S+L+ IFI+ +F+ LHC RN IH++LFV+ +LR+                  F  +  NN TN              CKV + +  Y +  N+ W+ VE LYLH+++ +  F   S  ++ + L+GWG+P + +  W ++R    +  CW+     I    W+  V P+L  I  N I F+ ++ +L  K+         ++ ++RKLA+S LVL+ VFG++ ++FV +      H    + ++++M  E   NS QGF +++++C+CN EV  EIK+
Sbjct:   62 EITAEEQVQMLLDAKLQCLQKVSSDDPA-----VGVCVPEWDGLICWPQGF-PGTLTKTPCPGYIYDFNHAAHAYRRCDSNGSWVLAESSNKTWVNYTECIKSPEPNKKRQVFFERLHIMYTVGYAVSFSSLLVAIFIIGYFRRLHCTRNYIHMHLFVSFMLRAASIFVKDHVVHTSAGLQEFDAVLMNNFTNAVDVAPVDTSQYMGCKVTVLLFIYFLATNYYWILVEGLYLHSLIFM-AFLSDSKYLWGFTLIGWGVPAVFVAAWAVVRATLADARCWELSAGNIK---WIYQV-PILTAIGLNFILFVNIVRVLATKIRETNAGRYDTRKQYRKLAKSTLVLVFVFGVHYIVFVGMP-----HTFEGLGWEVRMYCELFFNSFQGFFVSIIYCYCNGEVQTEIKK 453          

Query:   52 VWILLTFIWCPFLQGKSIR----KLEYKIEHDSQETLLRKAQENCNSKISNFSIAKLSLNTSFCRPVWDGVVCWYGYFQSGKTASQPCPHYIDKFIRKGKVYKRCTVNGEWFRRANSTKPWTDFGEC----KQSTNKEPALFF--VVTISNIGFFISITSVLLGIFILRFFKNLHCDRNTIHINLFVACLLRSCFSLF----------------SQLQTN---------NETNTF-CKVFMSMHNYLIMANFTWVFVEALYLHNVLTLHTFKETSGVVFLYILVGWGXXXXXXXXXXXXXXVFDNTYCWDAGDSQITLDMWVLFVYPVLLLIQ-NIIFFIKLIVILHAKM--VTHQLTASQNKFRKLARSILVLMVVFGIYQLIFVPLDLIENMHN-NKVTFQIKMCAEHLINSAQGFLLAMMFCFCNSEVLKEIKRKF 1248
            +WI+L +I    L G S+       E  +    Q  LL   +  C   IS  + A        C P WDG+VCW      G     PCP Y+  F   G  Y++C+ NG W    N T  W ++ +C         K    FF  +  +  +G+ +S +S+L+ IFI+ +F+ LHC RN IH++LFV+ +LR+  S+F                + L  N         ++T  F CK+ +    Y +  N+ W+ VE LYLH+++ +  F + S  ++ + L+GWG+P + +  W ++R    +  CW+     I    W+  V P+L  I  N I F+ ++ +L  K+         ++ ++RKLA+S LVL++VFG++ ++FV +      H    + ++++M  E   NS QGF +++++CFCN EV  EI++ +
Sbjct:    1 MWIILVWISVQVLLGTSVEAQHVDPEVGLTAQEQVLLLYDIKLQCLQNISEHNPAD-----EVCSPGWDGLVCW-PQGSPGTVTKVPCPSYVYDFNHNGFAYRQCSSNGSWVSVENRT--WVNYSDCLRFLAPGIEKGKRDFFERLHIMYTVGYAVSFSSLLVAIFIIGYFRRLHCTRNYIHMHLFVSFMLRA-ISIFVKDRVVYANGVLQEYDTMLMDNISTVSISPLDKTQYFGCKITVLFFIYFLATNYYWILVEGLYLHSLIFMAFFSD-SKYLWGFTLIGWGVPALFVSTWAVVRATLADARCWELSAGNIK---WIYQV-PILTAIGLNFILFVNIVRVLATKIRETNAGRYDTRKQYRKLAKSTLVLVLVFGVHYIVFVGMP-----HTFTGLGWELRMYCELFFNSFQGFFVSIIYCFCNGEVQAEIRKTW 420          

Query:  130 HDSQETLLRKAQENCNSKISNFSIAKLS----LNTSFCRPVWDGVVCWYGYFQSGKTASQPCPHYIDKFIRKGKVYKRCTVNGEWFRRANSTKPWTDFGECKQ---STNKEPALF-FVVTISNIGFFISITSVLLGIFILRFFKNLHCDRNTIHINLFVACLLRS-----------CFSLFSQLQTNNETN---------------TFCKVFMSMHNYLIMANFTWVFVEALYLHNVLTLHTFKETSGVVFLYILVGWGXXXXXXXXXXXXXXVFDNTYCWDAGDSQITLDMWVLFVYPVLLLIQNIIFFIKLIVILHAKM--VTHQLTASQNKFRKLARSILVLMVVFGIYQLIFVPLDLIENMHNNKVTFQIKMCAEHLINSAQGFLLAMMFCFCNSEVLKEIKRKFEN-------HRNSRSLQTT 1284
            H +Q  L+ K  EN   +    ++ +      L    C P WDGVVCW      G T S  CP YI  F  KG  Y+RC +NG W     + + W ++ EC +   +  KE  +F  +  I  +G+ IS+ S+ + + IL +F+ LHC RN IH++LF++ +LR+             S   + +  +E +                 CKV ++   Y +  N+ W+ VE LYLH+++ +  F      ++ + L GWG+P I ++IW   R    +T CWD     +    W++ V  +  ++ N   FI ++ +L  K+         ++ ++RKL +S LVLM +FG++ ++F+     E    + + +Q++M  E L NS QGF +A+++CFCN EV  EIK+ +          R +RS  TT
Sbjct:   47 HGNQWCLISKQGENKKGREEIDALPQGPQPFLLRNGLCLPEWDGVVCWPEGL-PGNTVSISCPEYIQDFNHKGHAYRRCDMNGSWELVPGNNRTWANYTECAKYLFNETKEREVFDRLYLIYTVGYSISLGSLTVAVLILGYFRRLHCTRNYIHMHLFISFMLRAGSIFVKDAVLYSGSALEETELISEEDLKFITEIPPADKMQFVGCKVVVTFFLYFLATNYYWILVEGLYLHSLIFM-AFISDKKYLWGFTLFGWGVPAIFVLIWARERATVADTGCWDLSAGYLK---WIVQVPILAAIMVNFGLFINIVRVLATKLRETNAGRCDTRQQYRKLLKSTLVLMPLFGVHYIVFMAFPYTE---VSGILWQVQMHYELLFNSFQGFFVAIIYCFCNGEVQAEIKKSWSRWTLALDFKRKARSGSTT 466          

Query:  124 IEHDSQETLLRKAQENCNSKISNFSIAKLSLNTSFCRPVWDGVVCWYGYFQSGKTASQPCPHYIDKFIRKGKVYKRCTVNGEWFRRANSTKPWTDFGECKQ---STNKEPALF-FVVTISNIGFFISITSVLLGIFILRFFKNLHCDRNTIHINLFVACLLRS-----------CFSLFSQLQTNNETN---------------TFCKVFMSMHNYLIMANFTWVFVEALYLHNVLTLHTFKETSGVVFLYILVGWGXXXXXXXXXXXXXXVFDNTYCWDAGDSQITLDMWVLFVYPVLLLIQNIIFFIKLIVILHAKM--VTHQLTASQNKFRKLARSILVLMVVFGIYQLIFVPLDLIENMHNNKVTFQIKMCAEHLINSAQGFLLAMMFCFCNSEVLKEIKRKFEN-------HRNSRSLQTT 1284
            I  + Q  LL  A+  C   +S+ S +K   +   C P WDGVVCW      G T S  CP YI  F  KG  Y+RC +NG W     + + W ++ EC +   +  KE  +F  +  I  +G+ IS+ S+ + + IL +F+ LHC RN IH++LF++ +LR+             S   + +  +E +                 CKV ++   Y +  N+ W+ VE LYLH+++ +  F      ++ + L GWG+P I ++IW   R    +T CWD     +    W++ V  +  ++ N   FI ++ +L  K+         ++ ++RKL +S LVLM +FG++ ++F+     E    + + +Q++M  E L NS QGF +A+++CFCN EV  EIK+ +          R +RS  TT
Sbjct:   33 ITKEEQILLLWNAKALCEKLLSS-SASKA--HDGLCLPEWDGVVCWPEGL-PGNTVSISCPEYIQDFNHKGHAYRRCDMNGSWELVPGNNRTWANYTECAKYLFNETKEREVFDRLYLIYTVGYSISLGSLTVAVLILGYFRRLHCTRNYIHMHLFISFMLRAGSIFVKDAVLYSGSALEETELISEEDLKFITEIPPADKMQFVGCKVVVTFFLYFLATNYYWILVEGLYLHSLIFM-AFISDKKYLWGFTLFGWGVPAIFVLIWARERATVADTGCWDLSAGYLK---WIVQVPILAAIMVNFGLFINIVRVLATKLRETNAGRCDTRQQYRKLLKSTLVLMPLFGVHYIVFMAFPYTE---VSGILWQVQMHYELLFNSFQGFFVAIIYCFCNGEVQAEIKKSWSRWTLALDFKRKARSGSTT 447          

Query:  124 IEHDSQETLLRKAQENCNSKISNFSIAKLSLN--------TSFCRPVWDGVVCWYGYFQSGKTASQPCPHYIDKFIRKGKVYKRCTVNGEWFRRANSTKPWTDFGECKQ---STNKEPALF-FVVTISNIGFFISITSVLLGIFILRFFKNLHCDRNTIHINLFVACLLRS-----------CFSLFSQLQTNNETN---------------TFCKVFMSMHNYLIMANFTWVFVEALYLHNVLTLHTFKETSGVVFLYILVGWGXXXXXXXXXXXXXXVFDNTYCWDAGDSQITLDMWVLFVYPVLLLIQNIIFFIKLIVILHAKM--VTHQLTASQNKFRKLARSILVLMVVFGIYQLIFVPLDLIENMHNNKVTFQIKMCAEHLINSAQGFLLAMMFCFCNSEVLKEIKRKFEN-------HRNSRSLQTT 1284
            I  + Q  LL  A+  C   +S+ +    ++N           C P WDGVVCW      G T S  CP YI  F  KG  Y+RC +NG W     + + W ++ EC +   +  KE  +F  +  I  +G+ IS+ S+ + + IL +F+ LHC RN IH++LF++ +LR+             S   + +  +E +                 CKV ++   Y +  N+ W+ VE LYLH+++ +  F      ++ + L GWG+P I ++IW   R    +T CWD     +    W++ V  +  ++ N   FI ++ +L  K+         ++ ++RKL +S LVLM +FG++ ++F+     E    + + +Q++M  E L NS QGF +A+++CFCN EV  EIK+ +          R +RS  TT
Sbjct:   14 ITKEEQILLLWNAKALCEKLLSSSASKAHAINKLLNLPFADGLCLPEWDGVVCWPEGL-PGNTVSISCPEYIQDFNHKGHAYRRCDMNGSWELVPGNNRTWANYTECAKYLFNETKEREVFDRLYLIYTVGYSISLGSLTVAVLILGYFRRLHCTRNYIHMHLFISFMLRAGSIFVKDAVLYSGSALEETELISEEDLKFITEIPPADKMQFVGCKVVVTFFLYFLATNYYWILVEGLYLHSLIFM-AFISDKKYLWGFTLFGWGVPAIFVLIWARERATVADTGCWDLSAGYLK---WIVQVPILAAIMVNFGLFINIVRVLATKLRETNAGRCDTRQQYRKLLKSTLVLMPLFGVHYIVFMAFPYTE---VSGILWQVQMHYELLFNSFQGFFVAIIYCFCNGEVQAEIKKSWSRWTLALDFKRKARSGSTT 439          

Query:  124 IEHDSQETLLRKAQENCNSKISNFSIAKLSLN--------TSFCRPVWDGVVCWYGYFQSGKTASQPCPHYIDKFIRKGKVYKRCTVNGEWFRRANSTKPWTDFGECKQ---STNKEPALF-FVVTISNIGFFISITSVLLGIFILRFFKNLHCDRNTIHINLFVACLLRS-----------CFSLFSQLQTNNETN---------------TFCKVFMSMHNYLIMANFTWVFVEALYLHNVLTLHTFKETSGVVFLYILVGWGXXXXXXXXXXXXXXVFDNTYCWDAGDSQITLDMWVLFVYPVLLLIQNIIFFIKLIVILHAKM--VTHQLTASQNKFRKLARSILVLMVVFGIYQLIFVPLDLIENMHNNKVTFQIKMCAEHLINSAQGFLLAMMFCFCNSEVLKEIKRKFEN-------HRNSRSLQTT 1284
            I  + Q  LL  A+  C   +S+ +    ++N           C P WDGVVCW      G T S  CP YI  F  KG  Y+RC +NG W     + + W ++ EC +   +  KE  +F  +  I  +G+ IS+ S+ + + IL +F+ LHC RN IH++LF++ +LR+             S   + +  +E +                 CKV ++   Y +  N+ W+ VE LYLH+++ +  F      ++ + L GWG+P I ++IW   R    +T CWD     +    W++ V  +  ++ N   FI ++ +L  K+         ++ ++RKL +S LVLM +FG++ ++F+     E    + + +Q++M  E L NS QGF +A+++CFCN EV  EIK+ +          R +RS  TT
Sbjct:   31 ITKEEQILLLWNAKALCEKLLSSSASKAHAINKLLNLPFADGLCLPEWDGVVCWPEGL-PGNTVSISCPEYIQDFNHKGHAYRRCDMNGSWELVPGNNRTWANYTECAKYLFNETKEREVFDRLYLIYTVGYSISLGSLTVAVLILGYFRRLHCTRNYIHMHLFISFMLRAGSIFVKDAVLYSGSALEETELISEEDLKFITEIPPADKMQFVGCKVVVTFFLYFLATNYYWILVEGLYLHSLIFM-AFISDKKYLWGFTLFGWGVPAIFVLIWARERATVADTGCWDLSAGYLK---WIVQVPILAAIMVNFGLFINIVRVLATKLRETNAGRCDTRQQYRKLLKSTLVLMPLFGVHYIVFMAFPYTE---VSGILWQVQMHYELLFNSFQGFFVAIIYCFCNGEVQAEIKKSWSRWTLALDFKRKARSGSTT 456          

Query:  124 IEHDSQETLLRKAQENCNSKISNFSIAKLSLNTSFCRPVWDGVVCWYGYFQSGKTASQPCPHYIDKFIRKGKVYKRCTVNGEWFRRANSTKPWTDFGECKQ---STNKEPALF-FVVTISNIGFFISITSVLLGIFILRFFKNLHCDRNTIHINLFVACLLRS-----------CFSLFSQLQTNNETN---------------TFCKVFMSMHNYLIMANFTWVFVEALYLHNVLTLHTFKETSGVVFLYILVGWGXXXXXXXXXXXXXXVFDNTYCWDAGDSQITLDMWVLFVYPVLLLIQNIIFFIKLIVILHAKM--VTHQLTASQNKFRKLARSILVLMVVFGIYQLIFVPLDLIENMHNNKVTFQIKMCAEHLINSAQGFLLAMMFCFCNSEVLKEIKRKFEN-------HRNSRSLQTT 1284
            I  + Q  LL  A+  C          KL  +   C P WDGVVCW      G T S  CP YI  F  KG  Y+RC +NG W     + + W ++ EC +   +  KE  +F  +  I  +G+ IS+ S+ + + IL +F+ LHC RN IH++LF++ +LR+             S   + +  +E +                 CKV ++   Y +  N+ W+ VE LYLH+++ +  F      ++ + L GWG+P I ++IW   R    +T CWD     +    W++ V  +  ++ N   FI ++ +L  K+         ++ ++RKL +S LVLM +FG++ ++F+     E    + + +Q++M  E L NS QGF +A+++CFCN EV  EIK+ +          R +RS  TT
Sbjct:   44 ITKEEQILLLWNAKALCE---------KLLSSNGLCLPEWDGVVCWPEGL-PGNTVSISCPEYIQDFNHKGHAYRRCDMNGSWELVPGNNRTWANYTECAKYLFNETKEREVFDRLYLIYTVGYSISLGSLTVAVLILGYFRRLHCTRNYIHMHLFISFMLRAGSIFVKDAVLYSGSALEETELISEEDLKFITEIPPADKMQFVGCKVVVTFFLYFLATNYYWILVEGLYLHSLIFM-AFISDKKYLWGFTLFGWGVPAIFVLIWARERATVADTGCWDLSAGYLK---WIVQVPILAAIMVNFGLFINIVRVLATKLRETNAGRCDTRQQYRKLLKSTLVLMPLFGVHYIVFMAFPYTEV---SGILWQVQMHYELLFNSFQGFFVAIIYCFCNGEVQAEIKKSWSRWTLALDFKRKARSGSTT 452          

Query:  133 DSQETLLRKAQENCNSKISNFSIAKLSLNTSFCRPVWDGVVCWYGYFQSGKTASQPCPHYIDKFIRKGKVYKRCTVNGEWFRRANSTKPWTDFGEC--KQSTNKEPALFF--VVTISNIGFFISITSVLLGIFILRFFKNLHCDRNTIHINLFVACLLRSCFSLF---------------SQLQTNNETNTF-------------CKVFMSMHNYLIMANFTWVFVEALYLHNVLTLHTFKETSGVVFLYILVGWGXXXXXXXXXXXXXXVFDNTYCWD--AGDSQITLDMWVLFVYPVLLLIQ-NIIFFIKLIVILHAKM-----VTHQLTASQNKFRKLARSILVLMVVFGIYQLIFVPLDLIENMHNNKVTFQIKMCAEHLINSAQGFLLAMMFCFCNSEVLKEIKR 1242
            + Q  L+ KA+  C   I+    A+L      C P WDG++CW      GK ++ PCP Y+  F  KG  ++ CT NG W     S K W ++ +C  +   N     FF  +  +  +G+ IS  S+ + I I+ +F+ LHC RN IH++LFV+ +LR+  S+F                 L    +   F             CK+ + M  Y +  N+ W+ VE LYLHN++ +  F +T   ++ +I +GWG P + ++ W + R    +T CW+  AGD  I       +  P+L  I  N I F+  + +L  K+     V H +   + ++RKLA+S LVL++VFG++ ++FV     +    + + ++I+M  E   NS QGF +++++C+CN EV  E+K+
Sbjct:   35 EEQIVLVMKAKMQCELNIT----AQLQEGEGNCFPEWDGIICW-PRGTVGKMSAVPCPPYVYDFNHKGVAFRHCTPNGTWDSIHGSNKTWANYSDCFLQPDINIGKQEFFESLYILYTVGYSISFGSLAVAILIIGYFRRLHCTRNYIHLHLFVSFMLRA-MSIFVKDRVAQAHLGVEALQSLVMQGDLQNFIGGPSVDKSQYVGCKIAVVMFIYFLATNYYWILVEGLYLHNLIFVSFFSDTK-YLWGFISIGWGFPAVFVVAWAVARATLADTRCWELSAGDRWI-------YQAPILAAIGLNFILFLNTVRVLATKIWETNAVGHDM---RKQYRKLAKSTLVLVLVFGVHYIVFV----CQPHSFSGLWWEIRMHCELFFNSFQGFFVSIVYCYCNGEVQAEVKK 423          

Query:  229 CRPVWDGVVCWYGYFQSGKTASQPCPHYIDKFIRKGKVYKRCTVNGEWFRRANSTKPWTDFGEC----KQSTNKEPALFFVVTISNIGFFISITSVLLGIFILRFFKNLHCDRNTIHINLFVACLLRSC---------FSLFSQLQTNNETN--------------------TFCKVFMSMHNYLIMANFTWVFVEALYLHNVLTLHTFKETSGVVFLYILVGWGXXXXXXXXXXXXXXVFDNTYCWDAGDSQITLDMWVLFVYPVLLLIQNIIFFIKLIVILHAKM--VTHQLTASQNKFRKLARSILVLMVVFGIYQLIFVPLDLIENMHNNKVTFQIKMCAEHLINSAQGFLLAMMFCFCNSEVLKEIKRKF 1248
            C P WD +VCW      G+  + PCP YI  F  KG  Y+RC  NG W       + W ++ EC       T +      +  I  +G+ +S+ S+ + + IL +F+ LHC RN IH+++F++ +LR+          +S F+  +    T                       C+V ++   Y +  N+ W+ VE LYLH+++ +  F E    ++ + + GWGLP + + +W+ +R    NT CWD          W++ V  +  ++ N I FI +I +L  K+         ++ ++RKL RS LVL+ +FG++  +F+ L   E    +   +QI+M  E L NS QGF +A+++CFCN EV  EI++ +
Sbjct:  108 CLPEWDNIVCW-PLGAPGEVVAVPCPDYIYDFNHKGHAYRRCDRNGSWEVVPGHNRTWANYSECLKFMTNETREREVFDRLGMIYTVGYSMSLASLTVAVLILAYFRRLHCTRNYIHMHMFLSFMLRAASIFVKDAVLYSGFTLDEAERLTEEELHIIAQVPPPPAAAAVGYAGCRVAVTFFLYFLATNYYWILVEGLYLHSLIFMAFFSEKK-YLWGFTIFGWGLPAVFVAVWVGVRATLANTGCWDLSSGH---KKWIIQVPILASVVLNFILFINIIRVLATKLRETNAGRCDTRQQYRKLLRSTLVLVPLFGVHYTVFMALPYTEV---SGTLWQIQMHYEMLFNSFQGFFVAIIYCFCNGEVQAEIRKSW 474          

Query:  229 CRPVWDGVVCWYGYFQSGKTASQPCPHYIDKFIRKGKVYKRCTVNGEWFRRANSTKPWTDFGEC----KQSTNKEPALFFVVTISNIGFFISITSVLLGIFILRFFKNLHCDRNTIHINLFVACLLRSC---------FSLFSQLQTNNETN--------------------TFCKVFMSMHNYLIMANFTWVFVEALYLHNVLTLHTFKETSGVVFLYILVGWGXXXXXXXXXXXXXXVFDNTYCWDAGDSQITLDMWVLFVYPVLLLIQNIIFFIKLIVILHAKM--VTHQLTASQNKFRKLARSILVLMVVFGIYQLIFVPLDLIENMHNNKVTFQIKMCAEHLINSAQGFLLAMMFCFCNSEVLKEIKRKF 1248
            C P WD +VCW      G+  + PCP YI  F  KG  Y+RC  NG W       + W ++ EC       T +      +  I  +G+ +S+ S+ + + IL +F+ LHC RN IH+++F++ +LR+          +S F+  +    T                       C+V ++   Y +  N+ W+ VE LYLH+++ +  F E    ++ + + GWGLP + + +W+ +R    NT CWD          W++ V  +  ++ N I FI +I +L  K+         ++ ++RKL RS LVL+ +FG++  +F+ L   E    +   +QI+M  E L NS QGF +A+++CFCN EV  EI++ +
Sbjct:  108 CLPEWDNIVCW-PLGAPGEVVAVPCPDYIYDFNHKGHAYRRCDRNGSWEVVPGHNRTWANYSECLKFMTNETREREVFDRLGMIYTVGYSMSLASLTVAVLILAYFRRLHCTRNYIHMHMFLSFMLRAASIFVKDAVLYSGFTLDEAERLTEEELHIIAQVPPPPAAAAVGYAGCRVAVTFFLYFLATNYYWILVEGLYLHSLIFMAFFSEKK-YLWGFTIFGWGLPAVFVAVWVGVRATLANTGCWDLSSGH---KKWIIQVPILASVVLNFILFINIIRVLATKLRETNAGRCDTRQQYRKLLRSTLVLVPLFGVHYTVFMALPYTEV---SGTLWQIQMHYEMLFNSFQGFFVAIIYCFCNGEVQAEIRKSW 474          

Query:  229 CRPVWDGVVCWYGYFQSGKTASQPCPHYIDKFIRKGKVYKRCTVNGEWFRRANSTKPWTDFGEC----KQSTNKEPALFFVVTISNIGFFISITSVLLGIFILRFFKNLHCDRNTIHINLFVACLLRSC---------FSLFSQLQTNNETN--------------------TFCKVFMSMHNYLIMANFTWVFVEALYLHNVLTLHTFKETSGVVFLYILVGWGXXXXXXXXXXXXXXVFDNTYCWDAGDSQITLDMWVLFVYPVLLLIQNIIFFIKLIVILHAKM--VTHQLTASQNKFRKLARSILVLMVVFGIYQLIFVPLDLIENMHNNKVTFQIKMCAEHLINSAQGFLLAMMFCFCNSEVLKEIKRKF 1248
            C P WD +VCW      G+  + PCP YI  F  KG  Y+RC  NG W       + W ++ EC       T +      +  I  +G+ +S+ S+ + + IL +F+ LHC RN IH+++F++ +LR+          +S F+  +    T                       C+V ++   Y +  N+ W+ VE LYLH+++ +  F E    ++ + + GWGLP + + +W+ +R    NT CWD          W++ V  +  ++ N I FI +I +L  K+         ++ ++RKL RS LVL+ +FG++  +F+ L   E    +   +QI+M  E L NS QGF +A+++CFCN EV  EI++ +
Sbjct:  108 CLPEWDNIVCW-PLGAPGEVVAVPCPDYIYDFNHKGHAYRRCDRNGSWEVVPGHNRTWANYSECLKFMTNETREREVFDRLGMIYTVGYSMSLASLTVAVLILAYFRRLHCTRNYIHMHMFLSFMLRAASIFVKDAVLYSGFTLDEAERLTEEELHIIAQVPPPPAAAAVGYAGCRVAVTFFLYFLATNYYWILVEGLYLHSLIFMAFFSEKK-YLWGFTIFGWGLPAVFVAVWVGVRATLANTGCWDLSSGH---KKWIIQVPILASVVLNFILFINIIRVLATKLRETNAGRCDTRQQYRKLLRSTLVLVPLFGVHYTVFMALPYTEV---SGTLWQIQMHYEMLFNSFQGFFVAIIYCFCNGEVQAEIRKSW 474          

Query:  217 NTSFCRPVWDGVVCWYGYFQSGKTASQPCPHYIDKFI-RKGKVYKRCTVNGEWFRRANSTKPWTDFGEC-----KQSTNKEPALFFVVTISNIGFFISITSVLLGIFILRFFKNLHCDRNTIHINLFVACLLRSC---------FSLFSQLQTNNETNTF--CKVFMSMHNYLIMANFTWVFVEALYLHNVLTLHTFKETSGVVFLYILVGWGXXXXXXXXXXXXXXVFDNTYCWDAGDSQITLDMWVLFVYPVLL-LIQNIIFFIKLIVILHAKMVTHQLTA-SQNKFRKLARSILVLMVVFGIYQLIFVPLDLIENMHNNKVTFQIKMCAEHLINSAQGFLLAMMFCFCNSEVLKEIKRKFE-------NHRNSRSLQTTDEVKIRENSYRKRRGNR-DSLKQTDHQV 1365
            N   C  VWD + CW      G+T + PCP     F  R G + K CT +G W      ++ + DF +       +  +K      V  I  +G+ +S+ S+  G  I+  F+ LHC RN IH+NLF++ +LR+          +S    L+ +++  ++  CK+ +    Y IMANF W+ VE LYLH +L        S     Y+L+GWG+P + I  W   RL  ++T CWD  D  I    W +   P+L+ ++ N   FI ++ IL  K+ +  +    Q+++++LA+S L+L+ +FG++ ++F    +         T+QI    E  + S QG ++A+++CF NSEV  E+KR++          R+ R    +      E++ +  RG+R  S  Q++  V
Sbjct:   47 NQRACSGVWDNITCWRPA-DVGETVTVPCPKVFSNFYSRPGNISKNCTSDG-W------SETFPDFIDACGYNDPEDESKISFYILVKAIYTLGYSVSLMSLTTGSIIICLFRKLHCTRNYIHLNLFLSFMLRAISVLVKDSVLYSSSGLLRCHDQPASWVGCKLSLVFFQYCIMANFYWLLVEGLYLHTLLV--AILPPSRCFLAYLLIGWGIPSVCIGAWTATRLSLEDTGCWDTNDHSIP---WWVIRMPILISIVVNFALFISIVRILLQKLTSPDVGGNDQSQYKRLAKSTLLLIPLFGVHYMVFAAFPI-----GISSTYQILF--ELCVGSFQGLVVAVLYCFLNSEVQCELKRRWRGLCLTQAGSRDYRLHSWSMSRNGSESALQIHRGSRTQSFLQSETSV 436          

Query:  127 EHDSQETLLRKAQENCNSKISNFSIAKLSLNTSFCRPVWDGVVCWYGYFQSGKTASQPCPHYIDKFIRKGKVYKRCTVNGEWFRRANSTKPWTDFGEC----KQSTNKEPALFFVVTISNIGFFISITSVLLGIFILRFFKNLHCDRNTIHINLFVACLLRSC------FSLFSQLQTN-------NETNTF-------------CKVFMSMHNYLIMANFTWVFVEALYLHNVLTLHTFKETSGVVFLYILVGWGXXXXXXXXXXXXXXVFDNTYCWDAGDSQITLDMWVLFVYPVLLLIQNIIFFIKLIVILHAKM--VTHQLTASQNKFRKLARSILVLMVVFGIYQLIFVPLDLIENMHNNKVTFQIKMCAEHLINSAQGFLLAMMFCFCNSEVLKEIKRKFEN-------HRNSRSLQTT 1284
            +    E L  +A+E+   ++S+ S     L   FC P WD +VCW      GK  + PCP YI  F  KG+ Y+RC  NG W     + + W ++ EC       T +      +  I  +G+ IS+ S+ + + IL +F+ LHC RN IH++LFV+ +LR+         L+S + T+        E   F             C+V +++  Y +  N+ W+ VE LYLH+++ +  F E    ++ + L GWGLP + + +W+ +R    NT CWD          W++ V  +  ++ N I FI +I +L  K+         ++ ++RKL +S LVLM +FG++ ++F+     E    + + +Q++M  E L NS QGF +A+++CFCN EV  EIK+ +          R +RS  +T
Sbjct:   77 KEKPAEKLYSQAEES--REVSDRS----RLQDGFCLPEWDNIVCWPAGV-PGKVVAVPCPDYIYDFNHKGRAYRRCDSNGSWELVPGNNRTWANYSECVKFLTNETREREVFDRLGMIYTVGYSISLGSLTVAVLILGYFRRLHCTRNYIHMHLFVSFMLRAVSIFIKDAVLYSGVSTDEIERITEEELRAFTEPPPADKAGFVGCRVAVTVFLYFLTTNYYWILVEGLYLHSLIFMAFFSEKK-YLWGFTLFGWGLPAVFVAVWVTVRATLANTECWDLSSGN---KKWIIQVPILAAIVVNFILFINIIRVLATKLRETNAGRCDTRQQYRKLLKSTLVLMPLFGVHYIVFMATPYTE---VSGILWQVQMHYEMLFNSFQGFFVAIIYCFCNGEVQAEIKKSWSRWTLALDFKRKARSGSST 487          

Query:  133 DSQETLLRKAQENCNSKISNFSIAKLSLNTSFCRPVWDGVVCWYGYFQSGKTASQPCPHYIDKFIRKGKVYKRCTVNGEWFRRANSTKPWTDFGEC--KQSTNKEPALFF--VVTISNIGFFISITSVLLGIFILRFFKNLHCDRNTIHINLFVACLLRSCFSLF---------------SQLQTNNETNTF-------------CKVFMSMHNYLIMANFTWVFVEALYLHNVLTLHTFKETSGVVFLYILVGWGXXXXXXXXXXXXXXVFDNTYCWD--AGDSQITLDMWVLFVYPVLLLIQ-NIIFFIKLIVILHAKM-----VTHQLTASQNKFRKLARSILVLMVVFGIYQLIFVPLDLIENMHNNKVTFQIKMCAEHLINSAQGFLLAMMFCFCNSEVLKEIKRKF 1248
            + Q  L+ KA+  C   I+    A+       C P WDG++CW     +GKT++ PCP Y+  F  KG  ++ CT NG W     S K W ++ +C  +   N     FF  +  +  +G+ IS  S+ + I I+ +F+ LHC RN IH++LFV+ +LR+  S+F                 L    +   F             CK+ + M  Y +  N+ W+ VE LYLHN++ +  F +T   ++ +IL+GWG P + ++ W + R    +T CW+  AGD  I       +  P+L  I  N I F+  + +L  K+     V H +   + ++RKLA+S LVL++VFG++ ++F+     +    + + ++I+M  E   NS QGF +++++C+CN EV  E+K+ +
Sbjct:   35 EEQIVLVMKAKMQCELNIT----AQFQEGEGNCFPEWDGLICW-PRGTAGKTSAMPCPSYVYDFNHKGVAFRHCTPNGTWDFIHGSNKTWANYSDCFLQPDINIGKQEFFENLYILYTVGYSISFGSLAVAILIIGYFRRLHCTRNYIHLHLFVSFMLRA-XSIFVKDRVAQAHLGVEALQSLVMQGDLQNFIGGPSVDKSQYVGCKIAVVMFIYFLATNYYWILVEGLYLHNLIFVSFFSDTK-YLWGFILIGWGFPAVFVVAWAVARATLADTRCWELSAGDRWI-------YXXPILAAIGLNFILFLNTVRVLATKIWETNAVGHDM---RKQYRKLAKSTLVLVLVFGVHYIVFI----CQPHSFSGLWWEIRMHCELFFNSFQGFFVSIVYCYCNGEVQAEVKKTW 425          

Query:  133 DSQETLLRKAQENCNSKISNFSIAKLSLNTSFCRPVWDGVVCWYGYFQSGKTASQPCPHYIDKFIRKGKVYKRCTVNGEWFRRANSTKPWTDFGEC--KQSTNKEPALFF--VVTISNIGFFISITSVLLGIFILRFFKNLHCDRNTIHINLFVACLLRSCFSLF---------------SQLQTNNETNTF-------------CKVFMSMHNYLIMANFTWVFVEALYLHNVLTLHTFKETSGVVFLYILVGWGXXXXXXXXXXXXXXVFDNTYCWD--AGDSQITLDMWVLFVYPVLLLIQ-NIIFFIKLIVILHAKM-----VTHQLTASQNKFRKLARSILVLMVVFGIYQLIFVPLDLIENMHNNKVTFQIKMCAEHLINSAQGFLLAMMFCFCNSEVLKEIKR 1242
            + Q  L+ KA+  C   I+    A+L      C P WDG++CW      GK ++ PCP Y+  F  KG  ++ CT NG W     S K W ++ +C  +   N     FF  +  +  +G+ IS  S+ + I I+ +F+ LHC RN IH++LFV+ +LR+  S+F                 L    +   F             CK+ + M  Y +  N+ W+ VE LYLHN++ +  F +T   ++ +I +GWG P + ++ W + R    +T CW+  AGD  I       +  P+L  I  N I F+  + +L  K+     V H +   + ++RKLA+S LVL++VFG++ ++FV     +    + + ++I+M  E   NS QGF +++++C+CN EV  E+K+
Sbjct:   35 EEQIVLVMKAKMQCELNIT----AQLQEGEGNCFPEWDGIICW-PRGTVGKMSAVPCPPYVYDFNHKGVAFRHCTPNGTWDSIHGSNKTWANYSDCFLQPDINIGKQEFFESLYILYTVGYSISFGSLAVAILIIGYFRRLHCTRNYIHLHLFVSFMLRA-MSIFVKDRVAQAHLGVEALQSLVMQGDLQNFIGGPSVDKSQYVGCKIAVVMFIYFLATNYYWILVEGLYLHNLIFVSFFSDTK-YLWGFISIGWGFPAVFVVAWAVARATLADTRCWELSAGDRWI-------YQAPILAAIGLNFILFLNTVRVLATKIWETNAVGHDM---RKQYRKLAKSTLVLVLVFGVHYIVFV----CQPHSFSGLWWEIRMHCELFFNSFQGFFVSIVYCYCNGEVQAEVKK 423          

Query:   34 FAMRLFVWILLTFIWCPFLQGKSIRKLEYKIEHDSQETLLRKAQENCNSKISNFSIAKLSLNTSFCRPVWDGVVCWYGYFQSGKTASQPCPHYIDKFIRKGKVYKRCTVNGEWFRRANSTKPWTDFGECKQ------STNKEPALFFVVTISNIGFFISITSVLLGIFILRFFKNLHCDRNTIHINLFVACLLRSCF---------------SLFSQLQTNNETNTF------------CKVFMSMHNYLIMANFTWVFVEALYLHNVLTLHTFKETSGVVFLYILVGWGXXXXXXXXXXXXXXVFDNTYCWD--AGDSQITLDMWVLFVYPVLLLIQ-NIIFFIKLIVILHAKM-----VTHQLTASQNKFRKLARSILVLMVVFGIYQLIFVPLDLIENMHN-NKVTFQIKMCAEHLINSAQGFLLAMMFCFCNSEVLKEIKR 1242
                L VW  L    C  L  ++    +  I  + Q  L+ KA+  C   I+    A+L      C P WDG++CW      GK ++ PCP YI  F  KG  ++ C  NG W    +  K W ++ +C +      S  K+     +  +  +G+ IS  S+ + I I+ +F+ LHC RN IH++LFV+ +LR+                  L S +  ++  N+             CK+ + M  Y +  N+ W+ VE LYLHN++ +  F +T   ++ +IL+GWG P   +  W + R    +  CW+  AGD +     W+ +  P+L  I  N I F+  + +L  K+     V H    ++ ++RKLA+S LVL++VFG++ ++FV L      H+   + ++I+M  E   NS QGF +++++C+CN EV  E+K+
Sbjct:    4 LGASLHVWGWLMLGSC--LLARAQLDSDGTITIEEQIVLVLKAKVQCELNIT----AQLQEGEGNCFPEWDGLICW-PRGTVGKISAVPCPPYIYDFNHKGVAFRHCNPNGTWDFMHSLNKTWANYSDCLRFLQPDISIGKQEFFERLYVMYTVGYSISFGSLAVAILIIGYFRRLHCTRNYIHMHLFVSFMLRATSIFVKDRVVHAHIGVKELESLIMQDDPQNSIEATSVDKSQYIGCKIAVVMFIYFLATNYYWILVEGLYLHNLIFVAFFSDTK-YLWGFILIGWGFPAAFVAAWAVARATLADARCWELSAGDIK-----WI-YQAPILAAIGLNFILFLNTVRVLATKIWETNAVGHD---TRKQYRKLAKSTLVLVLVFGVHYIVFVCLP-----HSFTGLGWEIRMHCELFFNSFQGFFVSIIYCYCNGEVQAEVKK 426          

Query:  229 CRPVWDGVVCWYGYFQSGKTASQPCPHYIDKFIRKGKVYKRCTVNGEWFRRANSTKPWTDFGEC----KQSTNKEPALFFVVTISNIGFFISITSVLLGIFILRFFKNLHCDRNTIHINLFVACLLRSC---------FSLFSQLQTNNETN--------------------TFCKVFMSMHNYLIMANFTWVFVEALYLHNVLTLHTFKETSGVVFLYILVGWGXXXXXXXXXXXXXXVFDNTYCWDAGDSQITLDMWVLFVYPVLLLIQNIIFFIKLIVILHAKM--VTHQLTASQNKFRKLARSILVLMVVFGIYQLIFVPLDLIENMHNNKVTFQIKMCAEHLINSAQGFLLAMMFCFCNSEVLKEIKRKF 1248
            C P WD +VCW      G+  + PCP YI  F  KG  Y+RC  NG W       + W ++ EC       T +      +  I  +G+ +S+ S+ + + IL +F+ LHC RN IH+++F++ +LR+          +S F+  +    T                       C+V ++   Y +  N+ W+ VE LYLH+++ +  F E    ++ + + GWGLP + + +W+ +R    NT CWD          W++ V  +  ++ N I FI +I +L  K+         ++ ++RKL RS LVL+ +FG++  +F+ L   E    +   +QI+M  E L NS QGF +A+++CFCN EV  EI++ +
Sbjct:  108 CLPEWDNIVCW-PLGAPGEVVAVPCPDYIYDFNHKGHAYRRCDRNGSWEVVPGHNRTWANYSECLKFMTNETREREVFDRLGMIYTVGYSMSLASLTVAVLILAYFRRLHCTRNYIHMHMFLSFMLRAASIFVKDAVLYSGFTLDEAERLTEEELHIIAQVPPPPAAAAVGYAGCRVAVTFFLYFLATNYYWILVEGLYLHSLIFMAFFSEKK-YLWGFTIFGWGLPAVFVAVWVGVRATLANTGCWDLSSGH---KKWIIQVPILASVVLNFILFINIIRVLATKLRETNAGRCDTRQQYRKLLRSTLVLVPLFGVHYTVFMALPYTEV---SGTLWQIQMHYEMLFNSFQGFFVAIIYCFCNGEVQAEIRKSW 474          

Query:   88 LQGKSIRKLEYKIEHDSQETLLRKAQENCNSKISNFSIAKLSLNTSFCRPVWDGVVCWYGYFQSGKTASQPCPHYIDKFIRKGKVYKRCTVNGEWFRRANSTKPWTDFGECKQ-----STNKEPALFF-VVTISNIGFFISITSVLLGIFILRFFKNLHCDRNTIHINLFVACLLRSCF--------------------------SLFSQLQTNNETNTFCKVFMSMHNYLIMANFTWVFVEALYLHNVLTLHTFKETSGVVFLYILVGWGXXXXXXXXXXXXXXVFDNTYCWDAGDSQITLDMWVLFVYPVLLLIQNIIFFIKLIVILHAKM--VTHQLTASQNKFRKLARSILVLMVVFGIYQLIFVPLDLIENMHNNKVTFQIKMCAEHLINSAQGFLLAMMFCFCNSEVLKEIKRKFENHRNSRSLQTTDEVKIRENSY 1314
            L  + + +++  +  + Q  LL KA+  C   + +    +  L   +C P WDG+VCW     SGK  S  CP YI  F  +G+ Y+RC+ NG W   A + K W ++ EC +     + N+E  +F  +  I  +G+ +S+ S+++ + IL +F+ LHC RN IH++LFV+ +LR+                            S+     +N      CK  +++  Y +  N+ W+ VE LYLH+++ + TF      ++ + ++GWG+P + + +W  +R  F +T CWD     +    W+  V  +  ++ N + F+ +I +L  K+         ++ ++RKL +S LVLM +FG++ +IF  +   E    + + +QI+M  E L NS QGFL+A+++CFCN EV  EIK+ +   R + +L    + +   N+Y
Sbjct:    5 LTSRPLGRMDDVLTKEEQIALLFKAKRKCEGLVKS---RQGKLPDGYCSPEWDGIVCW-PEGASGKLVSTSCPDYIYDFNHRGRTYRRCSSNGTWEISAANNKTWANYSECAKFLYHYNQNQEKDVFHRLYLIYTVGYSVSLGSLIVAVLILGYFRRLHCTRNYIHMHLFVSYMLRAVSIFVKDVVLYSGSALEDVQRVTVEELKSITEAPPSNKAHFIGCKAAVTLFMYFLATNYFWILVEGLYLHSLIFM-TFFSDRKYLWGFTMIGWGVPAMFVSVWATVRATFADTECWDLSAGNLK---WIYQVPILAAVVVNFVLFLNIIRVLATKLRETNAGRCDTRQQYRKLLKSTLVLMPLFGVHYIIFNAMPYTEV---SGIPWQIQMHYEMLFNSFQGFLVAIIYCFCNGEVQAEIKKSWS--RRTLALDFKRKARSGSNTY 434          

Query:  133 DSQETLLRKAQENCNSKISNFSIAKLSLNTSFCRPVWDGVVCWYGYFQSGKTASQPCPHYIDKFIRKGKVYKRCTVNGEWFRRANSTKPWTDFGECKQ-----STNKEPALF-FVVTISNIGFFISITSVLLGIFILRFFKNLHCDRNTIHINLFVACLLRSCF--------------------------SLFSQLQTNNETNTFCKVFMSMHNYLIMANFTWVFVEALYLHNVLTLHTFKETSGVVFLYILVGWGXXXXXXXXXXXXXXVFDNTYCWDAGDSQITLDMWVLFVYPVLLLIQNIIFFIKLIVILHAKMVTHQLT--ASQNKFRKLARSILVLMVVFGIYQLIFVPLDLIENMHNNKVTFQIKMCAEHLINSAQGFLLAMMFCFCNSEVLKEIKRKFENHRNSRSLQTTDEVKIRENSY 1314
            + Q  LL  A+  C   I     ++   +  FC P WDG+VCW      G+T +  CP YI  F  KG  Y+RC VNG W   A S K W ++ EC       + N+E  +F  +  I  IG+ IS+ S+++ + IL +F+ LHC RN IH++LFV+ +LR+                            S+     TN      CKV +++  Y +  N+ W+ VE LYLH+++ +  F +    +  + ++GWG+P + + +W  +R    +T CWD     +    W++ V  +  ++ N + F+ +I +L  K+         S+ ++RKL +S LVLM +FG++ ++F+ +   E    + V +QI+M  E L NS QGF +A+++CFCN EV  EIK+ +   R S +L    + +   N+Y
Sbjct:   31 EEQIYLLVNAKRKCERTIK----SRHKTSEGFCLPEWDGIVCW-PEGAPGRTITTTCPEYIYDFNHKGNAYRRCDVNGSW-ELAVSNKTWANYSECATYLSHYNQNQEREVFDRLYLIYTIGYSISLGSLMVAVVILGYFRRLHCTRNYIHMHLFVSFMLRAISIFVKDVVLYSGAALEEAERITVEDLKSITEAPPTNKTQFVGCKVVVTLFLYFLATNYYWILVEGLYLHSLIFMTFFSDRKKYLLGFTMIGWGVPAMFVTVWACVRATLADTECWDLSAGSLK---WIVQVPILTAIVVNFLLFLNIIRVLATKLRESNAGRCDSRQQYRKLLKSTLVLMPLFGVHYIVFMAMPYTE---VSGVPWQIQMHYEMLFNSFQGFFVAIIYCFCNGEVQAEIKKSWS--RRSLALDFKRKARSGSNTY 444          

Query:  139 QETLLRKAQENCNSKISNFSIAKLSLNTSFCRPVWDGVVCWYGYFQSGKTASQPCPHYIDKFIRKGKVYKRCTVNGEWFRRANSTKPWTDFGECKQSTNKE-PALFFV------VTISNIGFFISITSVLLGIFILRFFKNLHCDRNTIHINLFVACLLRSCFSLFSQ--------------------LQTNNE-TNTFCKVFMSMHNYLIMANFTWVFVEALYLHNVLTLHTFKETSGVVFLYILVGWGXXXXXXXXXXXXXXVFDNTYCWDAGDSQITLDMWVLFVYPVLLLIQNIIFFIKLIVILHAKMVTH-QLTASQNKFRKLARSILVLMVVFGIYQLIFVPLDLIENMHNNKVTFQIKMCAEHLINSAQGFLLAMMFCFCNSEVLKEIKRKFENHRNSRS 1272
            QE +  KA+ +C  ++ N       +    C   WD + CW     +G  A QPCP YI+KFI      K C  +GEWF  + +   WT++ +C  + N E P+   V      + ++N+G+ +SI  +L+ + ++ +FK LHC RNT+HINLFV  +LR+  S   +                    L  N++ T+  CK+ M+++ Y++ AN TW+FVE LYLH ++ +  F E S V   YI +GW  PL+ +I W+++R   D+  CW+   ++     W++      L++ N +FF+ ++ ++  KM T   + A   ++RK+A+S LVL+ +FGI+ ++F+    I+    + V   + +  E   NS QG  +A++FCF N EV  E+K+ ++ ++  R 
Sbjct:   15 QEQMRVKARLDCYQRMLN---ETAPIEGVHCPRRWDSIACWPPT-AAGVQAEQPCPDYINKFIVDENATKICKADGEWFISSETNHTWTNYSQCISTANPEVPSQLLVDHVPNLLILANVGYALSIVMLLVAVILMLYFKKLHCPRNTVHINLFVTFILRAVLSFLKENLMVQGVGLPQDVHTDKHGMLAFNHQGTHWECKLLMTVYMYILGANCTWIFVEGLYLHMLIFMAVFSENSSVA-QYIAIGWFSPLLFVIPWVVVRATLDDFMCWNVYTNKNYF--WIIRGPLTFLMVVNFLFFLNIVRVVFTKMSTGTAMEARGQRYRKMAKSTLVLIPLFGIHYMVFI---WIDPSRASDVVELVWLYFEMFFNSFQGVFIALLFCFFNGEVRAEVKKSWQRYQLRRG 411          

Query:  133 DSQETLLRKAQENCNSKISNFSIAKLSLNTSFCRPVWDGVVCWYGYFQSGKTASQPCPHYIDKFIRKGKVYKRCTVNGEWFRRANSTKPWTDFGECKQ-----STNKEPALFF-VVTISNIGFFISITSVLLGIFILRFFKNLHCDRNTIHINLFVACLLRSCF--------------------------SLFSQLQTNNETNTFCKVFMSMHNYLIMANFTWVFVEALYLHNVLTLHTFKETSGVVFLYILVGWGXXXXXXXXXXXXXXVFDNTYCWDAGDSQITLDMWVLFVYPVLLLIQNIIFFIKLIVILHAKM--VTHQLTASQNKFRKLARSILVLMVVFGIYQLIFVPLDLIENMHNNKVTFQIKMCAEHLINSAQGFLLAMMFCFCNSEVLKEIKRKFENHRNSRSLQTTDEVKIRENSY 1314
            + Q  LL KA+  C   + +    +  L   +C P WDG+VCW     SGK  S  CP YI  F  +G+ Y+RC+ NG W   A + K W ++ EC +     + N+E  +F  +  I  +G+ +S+ S+++ + IL +F+ LHC RN IH++LFV+ +LR+                            S+     +N      CK  +++  Y +  N+ W+ VE LYLH+++ + TF      ++ + ++GWG+P + + +W  +R  F +T CWD     +    W+  V  +  ++ N + F+ +I +L  K+         ++ ++RKL +S LVLM +FG++ +IF  +   E    + + +QI+M  E L NS QGFL+A+++CFCN EV  EIK+ +   R + +L    + +   N+Y
Sbjct:   26 EEQIALLFKAKRKCEGLVKS---RQGKLPDGYCSPEWDGIVCW-PEGASGKLVSTSCPDYIYDFNHRGRTYRRCSSNGTWEISAANNKTWANYSECAKFLYHYNQNQEKDVFHRLYLIYTVGYSVSLGSLIVAVLILGYFRRLHCTRNYIHMHLFVSYMLRAVSIFVKDVVLYSGSALEDVQRVTVEELKSITEAPPSNKAHFIGCKAAVTLFMYFLATNYFWILVEGLYLHSLIFM-TFFSDRKYLWGFTMIGWGVPAMFVSVWATVRATFADTECWDLSAGNLK---WIYQVPILAAVVVNFVLFLNIIRVLATKLRETNAGRCDTRQQYRKLLKSTLVLMPLFGVHYIIFNAMPYTEV---SGIPWQIQMHYEMLFNSFQGFLVAIIYCFCNGEVQAEIKKSWS--RRTLALDFKRKARSGSNTY 440          

Query:  133 DSQETLLRKAQENCNSKISNFSIAKLSLNTSFCRPVWDGVVCWYGYFQSGKTASQPCPHYIDKFIRKGKVYKRCTVNGEWFRRANSTKPWTDFGECKQ-----STNKEPALF-FVVTISNIGFFISITSVLLGIFILRFFKNLHCDRNTIHINLFVACLLRSCFSLF--------------------------SQLQTNNETN-TFCKVFMSMHNYLIMANFTWVFVEALYLHNVLTLHTFKETSGVVFLYILVGWGXXXXXXXXXXXXXXVFDNTYCWDAGDSQITLDMWVLFVYPVLLLIQNIIFFIKLIVILHAKM--VTHQLTASQNKFRKLARSILVLMVVFGIYQLIFVPLDLIENMHNNKVTFQIKMCAEHLINSAQGFLLAMMFCFCNSEVLKEIKRKFENHRNSRSLQTTDEVKIRENSY 1314
            + Q  LL KA+  C   ISN    K      +C P WDG+VCW      GK  S  CP YI  F  KG  Y+RC  NG W    N+ K W ++ EC +     + N E  +F  +  I  +G+ IS+ S+++ + IL +F+ LHC RN IH++LFV+ +LR   S+F                          ++    N+T    CKV +++  Y +  N+ W+ VE LYLH+++ + TF      ++ + L+GWG+P + + +W  +R    +T CWD     +    W++ V  +  ++ N + F+ +I +L  K+         ++ ++RKL +S LVLM +FG++ ++F+ +   E     +V +QI+M  E L NS QGF +A+++CFCN EV  E+K+ +   R + +L    + +   N+Y
Sbjct:   39 EEQIGLLFKAKRKCEVAISN----KHKPGDGYCSPEWDGIVCW-PEGSPGKLVSTACPEYIYDFNHKGLAYRRCDNNGTWELTTNNNKTWANYSECAKFLSHYNKNNEKEVFDRLYLIYTVGYSISLGSLMVAVVILGYFRRLHCTRNYIHMHLFVSFMLRG-ISIFVKDVVLYSGSALEDMERVSVEDLKSITEAPPANKTQFIGCKVAVTLFLYFLATNYYWILVEGLYLHSLIFM-TFFSDRKYLWGFTLIGWGVPAMFVTVWASVRATLADTECWDLSAGNLK---WIVQVPILTAIVVNFMLFLNIIRVLATKLRETNAGRCDTRQQYRKLLKSTLVLMPLFGVHYIVFMAMPYTEV---TEVPWQIQMHYEMLFNSFQGFFVAIIYCFCNGEVQAEMKKSWS--RRTLALDFKRKARSGSNTY 452          

Query:  133 DSQETLLRKAQENCNSKISNFSIAKLSLNTSFCRPVWDGVVCWYGYFQSGKTASQPCPHYIDKFIRKGKVYKRCTVNGEWFRRANSTKPWTDFGECKQ-----STNKEPALF-FVVTISNIGFFISITSVLLGIFILRFFKNLHCDRNTIHINLFVACLLRSCFSLF--------------------------SQLQTNNETN-TFCKVFMSMHNYLIMANFTWVFVEALYLHNVLTLHTFKETSGVVFLYILVGWGXXXXXXXXXXXXXXVFDNTYCWDAGDSQITLDMWVLFVYPVLLLIQNIIFFIKLIVILHAKMVTHQLT--ASQNKFRKLARSILVLMVVFGIYQLIFVPLDLIENMHNNKVTFQIKMCAEHLINSAQGFLLAMMFCFCNSEVLKEIKRKFENHRNSRSLQTTDEVKIRENSY 1314
            + Q  LL  A+  C   I     ++  L   FC P WDG++CW      G+T S  CP YI  F  KG  Y+RC +NG W    ++ K W ++ EC +       N+E  +F  +  I  IG+ IS+ S+++ + IL +F+ LHC RN IH++LFV+ +LR+  S+F                          ++    N+T    CK+ +++  Y +  N+ W+ VE LYLH+++ + TF      ++ + L+GWG+P + + +W  +R    +T CWD     +    W++ +  +  ++ N + F+ +I +L  K+         S+ ++RKL +S LVLM +FG++ ++F+ +   E    + + +QI+M  E L NS QGF +A+++CFCN EV  EIK+ +   R + +L    + +   N+Y
Sbjct:   24 EEQIYLLFNAKRKCERAIK----SRHRLPEGFCMPEWDGILCW-PEGAPGRTVSTACPEYIYDFNHKGHAYRRCDLNGSWELATSNNKTWANYSECAKFLHYNHQNQEREVFDRLYLIYTIGYSISLGSLMVAVVILGYFRRLHCTRNYIHMHLFVSFMLRA-ISIFVKDVVLYSGAVLEETERVTVEDLKSITEAPPANKTQFVGCKIAVTLFLYFLATNYYWILVEGLYLHSLIFM-TFFSDRKYLWGFTLIGWGVPAMFVTVWASVRATLADTECWDLSAGNLK---WIVQIPILTAIVVNFLLFLNIIRVLATKLRESNAGRCDSRQQYRKLLKSTLVLMPLFGVHYIVFMAMPYTEV---SGIPWQIQMHYEMLFNSFQGFFVAIIYCFCNGEVQAEIKKSWS--RRTLALDFKRKARSGSNTY 437          

Query:  133 DSQETLLRKAQENCNSKISNFSIAKLSLNTSFCRPVWDGVVCWYGYFQSGKTASQPCPHYIDKFIRKGKVYKRCTVNGEWFRRANSTKPWTDFGECKQ-----STNKEPALF-FVVTISNIGFFISITSVLLGIFILRFFKNLHCDRNTIHINLFVACLLRSCFSLF--------------------------SQLQTNNETN-TFCKVFMSMHNYLIMANFTWVFVEALYLHNVLTLHTFKETSGVVFLYILVGWGXXXXXXXXXXXXXXVFDNTYCWDAGDSQITLDMWVLFVYPVLLLIQNIIFFIKLIVILHAKMVTHQLT--ASQNKFRKLARSILVLMVVFGIYQLIFVPLDLIENMHNNKVTFQIKMCAEHLINSAQGFLLAMMFCFCNSEVLKEIKRKFENHRNSRSLQTTDEVKIRENSY 1314
            + Q  LL  A+  C   I     ++  L   FC P WDG++CW      G+T S  CP YI  F  KG  Y+RC +NG W    ++ K W ++ EC +       N+E  +F  +  I  IG+ IS+ S+++ + IL +F+ LHC RN IH++LFV+ +LR+  S+F                          ++    N+T    CK+ +++  Y +  N+ W+ VE LYLH+++ + TF      ++ + L+GWG+P + + +W  +R    +T CWD     +    W++ +  +  ++ N + F+ +I +L  K+         S+ ++RKL +S LVLM +FG++ ++F+ +   E    + + +QI+M  E L NS QGF +A+++CFCN EV  EIK+ +   R + +L    + +   N+Y
Sbjct:   38 EEQIYLLFNAKRKCERAIK----SRHRLPEGFCMPEWDGILCW-PEGAPGRTVSTACPEYIYDFNHKGHAYRRCDLNGSWELATSNNKTWANYSECAKFLHYNHQNQEREVFDRLYLIYTIGYSISLGSLMVAVVILGYFRRLHCTRNYIHMHLFVSFMLRA-ISIFVKDVVLYSGAVLEETERVTVEDLKSITEAPPANKTQFVGCKIAVTLFLYFLATNYYWILVEGLYLHSLIFM-TFFSDRKYLWGFTLIGWGVPAMFVTVWASVRATLADTECWDLSAGNLK---WIVQIPILTAIVVNFLLFLNIIRVLATKLRESNAGRCDSRQQYRKLLKSTLVLMPLFGVHYIVFMAMPYTEV---SGIPWQIQMHYEMLFNSFQGFFVAIIYCFCNGEVQAEIKKSWS--RRTLALDFKRKARSGSNTY 451          

Query:  121 KIEHDSQETLLRKAQENCNSKISNFSIAKLSLNTSFCRPVWDGVVCW-YGYFQSGKTASQPCPHYIDKFIRKGKVYKRCTVNGEWFRRANSTKPWTDFGECKQST--NKEPALFF--VVTISNIGFFISITSVLLGIFILRFFKNLHCDRNTIHINLFVACLLRSC--------------FSLFSQLQTNNETNTF------------CKVFMSMHNYLIMANFTWVFVEALYLHNVLTLHTFKETSGVVFLYILVGWGXXXXXXXXXXXXXXVFDNTYCWDAGDSQITLDMWVLFVYPVLLLIQ-NIIFFIKLIVILHAKM--VTHQLTASQNKFRKLARSILVLMVVFGIYQLIFVPLD-LIENMHNNKVTFQIKMCAEHLINSAQGFLLAMMFCFCNSEVLKEIKRKF 1248
            +I  + Q  +L  A+  C   +S+  +A        C   WDG++CW  GY   G  A  PCP YI  F   G  Y+RC  N  W    +  K W ++ EC +S   N+E  +FF  +  +  +G+ +S  S+L+ I I+ +F+ LHC RN IH++LFV+ +LR+                  F  +  NN TN              CKV + +  Y +  N+ W+ VE LYLH+++ +    +T   ++ + L+GWG+P + +  W I+R    ++ CW+     I    W+  V P+L  I  N I F+ ++ +L  K+         ++ ++RKLA+S LVL++VFG++ ++FV +   IE +      ++++M  E   NS QGF +++++CFCN EV  EIK+ +
Sbjct:   18 EITAEEQVQMLLDARLQCLQTVSSHDLA-----VDECPAEWDGLICWPRGY--PGTLAKVPCPRYIYDFNHAGHAYRRCDSNSSWLLGESLNKTWANYTECIKSPGPNRERQVFFERLHIMYTVGYAVSFGSLLVAILIIGYFRRLHCTRNYIHMHLFVSFMLRAVSIFVKDRVVHTSAGLQEFDAVLMNNFTNAVDVAPVDTSQYMGCKVTVLLFIYFLATNYYWILVEGLYLHSLIFMAFLSDTK-YLWGFTLIGWGVPAVFVATWAIVRATVADSRCWELSAGNIK---WIYQV-PILTAIGLNFILFVNIVRVLATKIRETNAGRYDTRKQYRKLAKSTLVLVLVFGVHYIVFVGMPHTIEGL-----GWEVRMYCELFFNSFQGFFVSIIYCFCNGEVQTEIKKTW 411          

Query:  121 KIEHDSQETLLRKAQENCNSKISNFSIAKLSLNTSFCRPVWDGVVCW-YGYFQSGKTASQPCPHYIDKFIRKGKVYKRCTVNGEWFRRANSTKPWTDFGECKQST--NKEPALFF--VVTISNIGFFISITSVLLGIFILRFFKNLHCDRNTIHINLFVACLLRSC--------------FSLFSQLQTNNETNTF------------CKVFMSMHNYLIMANFTWVFVEALYLHNVLTLHTFKETSGVVFLYILVGWGXXXXXXXXXXXXXXVFDNTYCWDAGDSQITLDMWVLFVYPVLLLIQ-NIIFFIKLIVILHAKM--VTHQLTASQNKFRKLARSILVLMVVFGIYQLIFVPLD-LIENMHNNKVTFQIKMCAEHLINSAQGFLLAMMFCFCNSEVLKEIKRKF 1248
            +I  + Q  +L  A+  C   +S+  +A        C   WDG++CW  GY   G  A  PCP YI  F   G  Y+RC  N  W    +  K W ++ EC +S   N+E  +FF  +  +  +G+ +S  S+L+ I I+ +F+ LHC RN IH++LFV+ +LR+                  F  +  NN TN              CKV + +  Y +  N+ W+ VE LYLH+++ +    +T   ++ + L+GWG+P + +  W I+R    ++ CW+     I    W+  V P+L  I  N I F+ ++ +L  K+         ++ ++RKLA+S LVL++VFG++ ++FV +   IE +      ++++M  E   NS QGF +++++CFCN EV  EIK+ +
Sbjct:   28 EITAEEQVQMLLDARLQCLQTVSSHDLA-----VDECPAEWDGLICWPRGY--PGTLAKVPCPRYIYDFNHAGHAYRRCDSNSSWLLGESLNKTWANYTECIKSPGPNRERQVFFERLHIMYTVGYAVSFGSLLVAILIIGYFRRLHCTRNYIHMHLFVSFMLRAVSIFVKDRVVHTSAGLQEFDAVLMNNFTNAVDVAPVDTSQYMGCKVTVLLFIYFLATNYYWILVEGLYLHSLIFMAFLSDTK-YLWGFTLIGWGVPAVFVATWAIVRATVADSRCWELSAGNIK---WIYQV-PILTAIGLNFILFVNIVRVLATKIRETNAGRYDTRKQYRKLAKSTLVLVLVFGVHYIVFVGMPHTIEGL-----GWEVRMYCELFFNSFQGFFVSIIYCFCNGEVQTEIKKTW 421          

Query:   46 LFVWILLTFIWCPFLQ-GKSIRKLEYKIEHDSQETLLRKAQENCNSKISNFSIAKLSLNTSFCRPVWDGVVCWYGYFQSGKTASQPCPHYIDKFIRKGKVYKRCTVNGEWFRRANSTKPWTDFGEC------KQSTNKEPALFFVVTISNIGFFISITSVLLGIFILRFFKNLHCDRNTIHINLFVACLLRSC---------FSLFSQLQTN------NETNTFCKVFMSMHNYLIMANFTWVFVEALYLHNVLTLHTFKETSGVVFLYILVGWGXXXXXXXXXXXXXXVFDNTYCWDAGDSQITLDMWVLFVYPVLLLIQNIIFFIKLIVILHAKM---VTHQLTASQNKFRKLARSILVLMVVFGIYQLIFVPLDLIENMHNNKVTFQIKMCAEHLINSAQGFLLAMMFCFCNSEVLKEIKRKFENHRNSRSLQTTDEVKIRENS 1311
            + V + +TFI+C  L   K++   +  I  D Q  LL  A+  C   I +    + S+  + C P WDG++CW    + G+  +  CP YI  F  +G  Y+ C V+G W +     + W+++ EC        +  +E     +  +   G+ IS+ S+L+ +FIL FFK LHC RN IH +LF + + R+          ++   +++T+            CK+ ++   Y +  N  W+ VE LYLH+++ +  F      ++   ++GWG+P + + IW+ +R    +T CWD     +    W+  V  +  ++ N   F+ +I +L +K+    T +L   Q ++RKL +S LVLM +FG++ ++F+ L   E      + +Q++M  E   NS QGF +A ++CFCN EV  E+K+ +   R S  L    + +I  ++
Sbjct:    2 MVVEVSVTFIFCCILMTAKALIDSDDVITRDEQIFLLIGARTKCERSIRS---QQGSIRENDCVPEWDGIICW-PRGKPGQLVAVLCPEYIYDFNHQGNAYRNCDVSGNWEQVPIINRTWSNYTECTTYLHSNHAGQQEAVFRRLHLMYTTGYSISLASLLVAVFILCFFKRLHCTRNYIHTHLFTSFICRAVSIFVKDAVLYTFAEEVETDYVVVDPRPPMVGCKLAVTFFLYFLATNHYWILVEGLYLHSLIFM-AFLSDKNYLWALTIIGWGVPALFVSIWVSVRASLADTQCWDISAGNLK---WIYQVPILAAIVVNFFLFLNIIRVLASKLWETNTGKLDPRQ-QYRKLLKSTLVLMPLFGVHYMVFMALPYTE---VTGLLWQVQMHYEMFFNSLQGFFVAFIYCFCNGEVQAEVKKAWL--RRSLVLDLKQKARITSSA 434          

Query:  124 IEHDSQETLLRKAQENCNSKISNFSIAKLSLNTSFCRPVWDGVVCWYGYFQSGKTASQPCPHYIDKFIRKGKVYKRCTVNGEWFRRANSTKPWTDFGECKQSTN------KEPALFFVVTISNIGFFISITSVLLGIFILRFFKNLHCDRNTIHINLFVACLLRSCFSLFSQ---LQTNNETN----------------TFCKVFMSMHNYLIMANFTWVFVEALYLHNVLTLHTFKETSGVVFLYILVGWGXXXXXXXXXXXXXXVFDNTYCWDAGDSQITLDMWVLFVY--PVLLLIQ-NIIFFIKLIVILHAKM--VTHQLTASQNKFRKLARSILVLMVVFGIYQLIFVPLDLIENMHNNKVTFQIKMCAEHLINSAQGFLLAMMFCFCNSEVLKEIKRKFENHRNSRSLQ 1278
            I  + Q  +L +A+ +C   I +      S   + C   WDG++CW  +   G    + CP YI  F   G  Y++C  NG W + + + + W ++ EC +  N      ++ ++  +  +  IG+ +S+ S+ + + IL  F+ LHC RN IH++LFV+ +LR+  S+F +   L ++NE                    C+V +++  Y +  ++ WV VE LYL++++ L TF   SG ++ + L+GWG P++ + +W   R    N+ CWD          W+ ++Y  P+L  +  N + F+ ++ +L  K+         S+ ++RKL +S LVLM +FG++ ++F  +   + +    + +QI+M  E   NS QGF +A+++CFCN EV  E+K+ +      ++L+
Sbjct:   16 ITKEEQMFMLTEAKTHCEKTIHS---TNASSADTHCTAEWDGLICW-PWGLPGSMVREKCPSYIYDFNAHGHAYRKCESNGTW-KMSTANRLWANYSECTEFLNPHVQAKEKESIHRLSILYTIGYSVSLASLAIALCILTVFRRLHCTRNYIHMHLFVSFMLRAA-SIFVKDGVLYSDNELRLATPGPSPPAEAPHIFAGCRVVVTLFLYCLATSYFWVLVEGLYLYSLIFL-TF-SASGRLWTFALIGWGFPVVFVFVWAAARATLANSQCWDLSAG------WLKWIYQAPILAAVAVNFVLFVNIVRVLATKLRETNAARQESRQQYRKLLKSTLVLMPLFGVHYVLFAAMPYTDVI---GLAWQIQMYYEMTFNSFQGFFVAIIYCFCNGEVRGEMKKLWSRWSLDQALK 413          

Query:  151 LRKAQENCNSKISNFSIAKLSLNTSFCRPVWDGVVCWYGYFQSGKTASQPCPHYIDKFIRKGKVYKRCTVNGEWFRRANSTKPWTDFGECKQSTNKEPAL---FFVVTISNIGFFISITSVLLGIFILRFFKNLHCDRNTIHINLFVACLLRSCFSL--FSQLQTNNE----TNTFCKVFMSMHNYLIMANFTWVFVEALYLHNVLTLHTFKETSGVVFLYILVGWGXXXXXXXXXXXXXXVFDNTYCWDAGDSQITLDMWVLFVYPVLLLIQNIIFFIKLIVILHAKM-VTHQLTASQNKFRKLARSILVLMVVFGIYQLIFVPLDLIENMHNNKVTFQIKMCAEHLINSAQGFLLAMMFCFCNSEVLKEIKR 1242
            + K Q  CN ++        S++   C   WDG +CW G   +G  A Q CP Y   F  + KV K C  +G+WFR  +S + W+++  C   T  +  +    F + ++  G  +SI  +L+ + I  +FK+L C R T+H NLF++ +L S  ++   + +  N E       +CKV    H Y++  N+ W+  E +YLH ++ +  F E    +F Y L+GWG P++  ++  + R ++ +  CW +  + +   ++++    V  L+ N+ F + ++ +L  K+ VTH+  A  + + K  R+ L+L+ + GI Q + VP    E        + +++   HLI   QGFL+A +FCFCN EV   +KR
Sbjct:   17 ISKMQYECNKRM--LLEPPYSVSRKHCNRTWDGWLCW-GDTMAGDVAVQHCPDYFPDFDLQEKVTKICNTDGQWFRHPDSNRTWSNYTLCNAFTADKLKMAVNLFYLAVTGHG--VSILVLLVSLTIFFYFKSLSCQRITLHKNLFMSYILNSIITIIQLTAVANNQELVASKPVWCKVLQFFHQYMMGCNYFWMLCEGIYLHTLIVVAVFAEKQH-LFWYYLLGWGFPIVPALMHAVARTIYYDDNCWISSATHL---LYIIHGPVVAALLVNLFFLLNIVRVLVTKLKVTHR--AETSMYMKAVRATLILVPLLGI-QFVLVPWK-PERFVGEIYDYIMQIFPTHLI---QGFLVATIFCFCNGEVQAALKR 374          

Query:  214 LNTSFCRPVWDGVVCWYGYFQSGKTASQPCPHY---IDKFIRKGKVYKRCTVNGEWFRRANSTKPWTDFGECKQSTN------KEPALFFVVT-ISNIGFFISITSVLLGIFILRFFKNLHCDRNTIHINLFVACLLRSCFSLFSQLQ-TNN-----------------ETNTFCKVFMSMHNYLIMANFTWVFVEALYLHNVLTLHTFKETSGVVFLYILVGWGXXXXXXXXXXXXXXVFDNTYCWDAGDSQITLDMWVLFVYPVLL-LIQNIIFFIKLIVILHAKMVTHQLTASQNKFR 1029
            L+  +C   +D   CW       K A  PCP Y   IDK +  G VY+ CT +G W  + N T  W D  EC    N      KE  L   +  +   G+ +S+ S+++ + IL  F+ LHC RN IH+NLF + +LR+   L      T+N                 E  T C+       Y I AN+ W+ VE  YLH +LT+  F +   + F Y+L+GWG P++ II W++ +L+++N  CW        + +W L   P+L  ++ N I F+K+I IL +K+   Q   S  K R
Sbjct:   28 LSGVYCNRTFDHYACWPDSLPDTKVAI-PCPSYLPWIDK-VEGGYVYRYCTRDGTWLTQDNVTAAWRDHSECLDDENNISTEGKEMYLLHALRLVYTTGYSVSLASLVVAMGILIMFRRLHCTRNYIHMNLFASFILRAISVLLKDAALTHNYTKRPQNASDWLGYFGYEGYTGCRATHVFMQYCIGANYFWLLVEGSYLHTLLTMCVFTKKKLIAF-YVLLGWGTPIMFIIPWMVSKLIYENQGCWGI---NTWMGIWWLIRGPILFSIVVNCILFVKIIKILLSKLKAQQSKFSNYKSR 322          

Query:  256 CWYGYFQSGKTASQPCPHYID--KFIRKGKVYKRCTVNGEWFRRANST--KPWTDFGECKQSTNKEPALFFVVTISNIGFFISITSVLLGIFILRFFKNLHCDRNTIHINLFVACLLRSCFSLFSQ---LQTNNETNTFCKVFMSMHNYLIMANFTWVFVEALYLHNVLTLHTFKETSGVVFLYILVGWGXXXXXXXXXXXXXXVFDNTYCWDAGDSQITLDMWVLFVYPVLL-LIQNIIFFIKLIVILHAKMVTHQLTASQNKFRKLARSILVLMVVFGI-YQLIFVPLDLIENMHNNKVTFQIKMCAEHLINSAQGFLLAMMFCFCNSEVLKEIKRKF----ENHR 1260
            CW    ++G+T + PCP   +  ++     V + C  NG W +R+N +  KP  D    K+  ++   +  +V  + +G  IS+ +++       + +++ C RN IH +L    +LR+   L  Q   L T      +C+V +++ NY  + NF W+FVE  YLH  + + T+        +++ +GW +P   II+W +++L +++  CW        +D   ++  P++L L+ N IF   ++ IL  K+     + +    RK  ++ LVL+ + GI Y L FV      N   + V+  I +     + S QGF +++ +CF N EV   +++++    +NHR
Sbjct:   52 CW-PESEAGRTVATPCPERFNGVRYDSSKSVIRECLANGTWAQRSNYSLCKPIID---AKKPNSQHYKIALIV--NYLGHCISLAALITAFGFFWWLRSIRCLRNAIHWHLVTTFILRNAAWLLLQIIDLSTQERNEPWCRVVITVFNYFQVTNFFWMFVEGCYLHTAIVM-TYSTDKLRKSIFVCIGWCIPAPIIIVWAMVKLFYEDEKCWFGKTEGKYIDY--IYQGPIILVLLVNFIFLFNIVRILMTKLRASTTSETIQYSRKAVKATLVLLPLLGITYMLFFV------NPGEDPVSQVIFIYVNSFLMSFQGFFVSVFYCFLNGEVRSALRKRWNRWMDNHR 384          

Query:  226 FCRPVWDGV-VCWYGYFQSGKTASQPCPHYID--KFIRKGKVYKRCTVNGEWFRRANSTKPWTDFGECKQSTNKEPALFFVVTISNIGFFISITSVLLGIFILRFFKNLHCDRNTIHINLFVACLLRSCFSLFSQL---QTNNETNTFCKVFMSMHNYLIMANFTWVFVEALYLHNVLTLHTFKETSGVVFLYILVGWGXXXXXXXXXXXXXXVFDNTYCWDAGDSQITLDMWVLFVYPVLL-LIQNIIFFIKLIVILHAKMVTHQLTASQNKFRKLARSILVLMVVFGI-YQLIFVPLDLIENMHNNKVTFQIKMCAEHLINSAQGFLLAMMFCFCNSEVLKEIKRKF----ENH----RNSRSLQ-TTDEVKIRENSYRK 1320
            FC    D +  CW    ++ +   +PCP   +  ++     VY+ C  +  W RR+N +         + S + + AL     ++ +G  +S+ +++    I    +++ C RN IH NL    +LR+      QL    T      +C + +++ NY  + NF W+FVE  YLH  + + T+       +++I +GW +P   IIIW +++L F++  CW        +D   ++  P++L L+ N IF   ++ IL  K+     T+   ++RK  ++ LVL+ + GI Y L FV      N   ++++  I +     + S QGF +++ +CF N EV   I++++    +NH    R +R++   T   +I  +S+++
Sbjct:   12 FCNATRDEIGTCWPSS-EASRVVIRPCPDRFNGVQYDTSKSVYRECMADATWARRSNYSLCEAIILSKRNSQHYKVAL----VVNYLGHCVSLLALMTAFTIFWCLRSIRCLRNAIHWNLMTTFILRNATWFLLQLIDLSTQERNEPWCCIIITIFNYFQVTNFFWMFVEGCYLHTAIVM-TYSTDKLRKWIFICIGWVIPAPIIIIWAMVKLHFEDEKCWFGKTPGKYIDY--IYQGPIILVLLINFIFLFNIVTILMTKL-RASTTSETIQYRKAVKATLVLLPLLGITYMLFFV------NPGEDEISQVIFLYVNSFLMSFQGFFVSVFYCFLNGEVRSAIRKRWHRWLDNHAIRARVTRAMSIPTSPTRISFHSFKR 378          

Query:  322 FIRKGKVYKRCTVNGEWFRRANSTK------PWTDFGECKQSTNKEPALF--FVVTISNIGFFISITSVLLGIFILRFFKNLHCDRNTIHINLFVACLLRSCFSLFSQLQTNNETNTFCKVFMSMHNYLIMANFTWVFVEALYLHNVLTLHTFKETSGVVFLYILVGWGXXXXXXXXXXXXXXVFDNTY--CWDAGDSQITLDMWVLFVYPVLLLIQNIIFFIKLIVILHAKMVTHQLTASQNK--FRKLARSILVLMVVFGIYQLI-FVPLDLIENMHNNKVTFQIKMCAEHLINSAQGFLLAMMFCFCNSEV 1224
            FI  G  +   ++ G      N+T+        T+F    +   K+P +   ++  I+ IG  +SI   +L I    F  +L  +R  IHINL  A L      LF    T+ E  + C     +  +  M+ FTW+ VE ++++  L +  F    G   +Y ++GWG  L      +        T   CW + +S     +W  FV P L++I   +  + +++ + A M+  +   S N    R L ++ + L+ + G+  L  F+  +      N  V F+       + NS QGFL+ + +C  +SEV
Sbjct:    1 FISDGSPHGSWSIEGCRLGPRNATQITCYCYHLTNFAILTRLKAKDPTVHDDYLTYITFIGLGLSIAGCVLTILTHLFLPSLRSERVFIHINLVTAILFAQI--LFIVGATHREPQSLCLSVAVLLYFFYMSVFTWMLVEGIHIY-CLVIRVFNSGRGRKKIYTVIGWGEFLSIFPSGMPAFRNSSTTSSRCWLSLESG---AIWA-FVAPALVVIAFNLVILFMVLRVTAVMLKDESQTSSNVCLSRALVKAFVTLLPILGLTWLFGFLAFN------NKTVMFEYLFA---IFNSMQGFLIFVFYCLLSSEV 298          

Query:  466 ISNIGFFISITSVLLGIFI-LRFFKNLHCDRNTIHINLFVACLLRSCFSLFSQLQTNNETNTFCKVFMSMHNYLIMANFTWVFVEALYLHNVLTLHTFKETSGVVFLYILVGWGXXXXXXXXXXXXXXVFDNTY------CWDAGDSQITLDMWVLFVYPVLLLIQNIIFFIKLIVILHAKMVTH--QLTASQNKFRKLARSILVLMVVFGIYQLIFVPLDLIENMHNNKVTFQIKMCAEHLINSAQGFLLAMMFCFCNSEV 1224
            IS IG  IS+ ++LL I + + F++++   R  + +N+ +A +   C  + ++  T   +   CK    + +Y ++A F W+  E   L+ ++      +    V  ++L GWG P I + I +         Y      CW + D+ +   +W      +++L+ NII F   +++L   M T   Q  +   K R   ++  V++ + GI  L F  L         K  F I       +NS QG ++ +  C  N +V
Sbjct:   61 ISTIGCAISLFAILLTIILTVAFWRSVRSPRAIVLLNICLA-VAAVCILVIAE-GTARNSQKGCKALAILLHYFLLAVFCWMLCEGALLYIIIVKVIGGKPEEKVKYFLLFGWGFPAIIVAISLGATQTKGYGYHGAQTACWLSVDNGL---IWAFVAPALVVLMINIIVF---VLVLRQTMGTRHVQNKSRDEKLRVAVKATAVILPLLGITWL-FGLLAFSAETVAFKYIFAI-------LNSLQGLMIFIFHCVLNKQV 306          

Query:  466 ISNIGFFISITSVLLGIFILRFFKNLHCDRNTIHINLFVACLLRSCFSLFSQLQTNNETNTFCKVFMSMHNYLIMANFTWVFVEALYLHNVLTLHTFKETSGVVFLYILVGWGXXXXXXXXXXXXXXVFDNT--YCWDAGDSQITLDMWVLFVYPVLLLIQNIIFFIKLIVILHAKM-----VTHQLTASQNKFRKLARSILVLMVVFGIYQLIFVPLDLIENMHNNKVTFQIKMCAEHLINSAQGFLLAMMFCFCNSEV 1224
            ++ IG  +SI  V L +  L     L  +R  IH NL +A  +     L    +   E+   CK++ ++  Y  M+ F+W+ VE ++L+ ++ +     T  ++  Y  +GWGLP+  ++I   +      T  +CW +        +W  F  P +++I      +  ++ L  K+     V+H+   S    R  AR  ++L+ + G+   IF     +E     +  F          NS QG ++    C  NSEV
Sbjct:   48 VTYIGCTLSILGVFLTVVTLISLPVLRSERTRIHCNLCIAVGVSQILFLAGGTEELVESKVGCKLYAALMFYAFMSVFSWMLVEGIHLYQMIIIAFI--TRAMMKFYYFIGWGLPMCIVVIASCISHKGYGTPNFCWLSLTDH---TIWA-FTGPAIVVILVNAVVLGAVLRLRTKLENNAEVSHRACLSILFLRTGARVSIMLLPLLGL-SWIFGLFTAMEGTLVIQYIFAAT-------NSLQGLMIFAFHCVGNSEV 293          

Query:  391 TKPWTDFGECKQSTN---KEPALFFVVTISNIGFFISITSVLLGIFILRFFKNLHCDRNTIHINLFVACLLRSCFSLFSQLQTNNETNTFCKVFMSMHNYLIMANFTWVFVEALYLHNVLTLHTFKETSGVVFLYILVGWGXXXXXXXXXXXXXXVFDNTY-----CWDAGDSQITLDMWVLFVYPVLLLIQNIIFFIKLIVILHAKMVTHQLTASQNK----FRKLARSILVLMVVFGIYQLIFVPLDLIENMHNNKVTFQIKMCAEHLINSAQGFLLAMMFCFCNSEV 1224
            T   T F    Q T+    EP    +  I+ IG  IS  ++L+ + I    ++L  +R+ IH+NL +A  L     L     T N+    C+V  +  +Y     FTW+  E ++L+ +  +  F+  +  +  Y + GWG      +I  I   +  N+Y     CW +    ++ D    F+ PV      II    LI+I+  K + +  +  +N      R   +  LVLM + G+       +  +  ++ + V FQ       + NS QGFL+ ++    N+EV
Sbjct:   20 THHLTSFAVLMQHTDIPLTEPEKLSLQIITYIGCGISSVALLITLVIFLSIESLSTERHRIHLNLVLALFLAQILFLSGINATGNKIG--CQVVAAFLHYFYTVAFTWMLNEGVHLY-LKVVKVFRIENVRLLHYYIFGWG---FPAVIVGISAAIKPNSYGTESICWLS----LSDDFVWAFIGPVTF----IIAINCLILIVVVKTIVNSASTVKNSDHAHIRAGVKGALVLMPLLGVSW-----ISGLLAVNKDTVFFQYVFA---ITNSFQGFLIFLLHVVFNTEV 287          

Query:  442 PALFFVVTISN-IGFFISITSVLLGIFILRFFKNLH-CDRNTIHINLFVACLLRSCFSLFSQLQTNNETNTFCKVFMSMHNYLIMANFTWVFVEALYLHNVLTLHTFKETSGVVFLYILVGWG--XXXXXXXXXXXXXXVFDNTYCWDAGDSQITLDMWVLFVYPVLLL--IQNIIFFIKLIVILHAKMVTHQLTASQNKFRKLARSILVLMVVFGIYQLIFVPLDLIENMH 1119
            P + F + I   IG  +S+  +L+        + L   + N IH NL  A ++     L    +TN+   T C++   + +Y     FTW+ VE ++++  L+     +T  + F Y L GWG    ++ I   +      +N +CW A D  +   +W  F  PV+++  + ++  F    +  H     +     ++ +R   R+  V++ + G+  L+F  L + ++M 
Sbjct: 2230 PQVAFALRIGTYIGIAVSVAILLIAFVSFVCLRGLKKSNANDIHKNLVAAIVIAEIIFLAGINRTND--TTACRLVAILLHYFFSTVFTWMLVEGVHMYRRLSEKRNIDTGRMNFYYFL-GWGCPAIVVGISAGLSTEGYGNNHFCWMATDGTL---IWT-FTIPVMIVVAVSSMERFFFFTLPSHETFTCYFYLLMRSLYRAGMRASAVVLPLLGV-SLVFAILMVNKDME 2453          

Query:  133 DSQETLLRKAQENCNSKISNFSIAKLSLNTSFCRPVWDGVVCWYGYFQSGKTASQPCPHYIDKFIRKGKVYKRCTVNGEWFRRANSTKPWTDFGECKQ------STNKEPALFFVVTISNIGFFISITSVLLGIFILRFFKNLHCDRNTIHINLFVACLLRSC------FSLFSQLQTNN-ETNTF-------------------CKVFMSMHNYLIMANFTWVFVEALYLHNVLTLHTFKETSGVVFLYILVGWGXXXXXXXXXXXXXXVFDNTYCWDAGDSQITLDMWVLFVYPVLLLIQNIIFFIKLIVILHAKM--VTHQLTASQNKFRKLARSILVLMVVFGIYQLIFVPLDLIENMHNNKVTFQIKMCAEHLINSAQGFLLAMMFCFCNSEVLKEIKRKFENHRNSRSLQTTDEVKIRENS 1311
            + Q T L  A+  C + I++ S     +   FC   WDG+VCW      GK  S  CP YI  F  KG  Y+RC  NG W  +A++ K W ++ EC +       ++++     +  I  +G+ +S+ S+++ + IL +F+ LHC RN IH++LFV+ +LR+         L+S+    N E  T                    CKV +++  Y +  N+ W+ VE LYLH+++ + TF      ++ + L+GWG+P + + IW  +R  F +T CWD     +    W+  V  ++ ++ N I F+ +I +L  K+         ++ ++RKL +S LVLM +FG++ +IF  +   E    + + + I+M  E L NS QGFL+A+++CFCN EV  EIK+ +    N R+L    + K R  S
Sbjct:   33 EEQITQLVIAKHTCENNIASRS----KIPNGFCSAEWDGIVCW-PEGPPGKLVSTACPEYIYDFNHKGLAYRRCDNNGTW-EQASANKTWANYNECAKFLYHYNHSHEKEVFHRLYLIYTVGYSVSLGSLMVAVVILGYFRRLHCTRNYIHMHLFVSYMLRAISIFVKDVVLYSESPLENMERVTLDDLKSITIAPPVNKTQFIACKVVVTLFMYFLATNYYWILVEGLYLHSLIFM-TFFSDRKYLWGFTLIGWGVPAVFVSIWATVRATFADTECWDLSAGNLK---WIYQVPILMAVVVNFILFLNIIRVLATKLRETNAGRCDTRQQYRKLLKSTLVLMPLFGVHYIIFNAMPYTEV---SGIPWLIQMHYEMLFNSFQGFLVAIIYCFCNGEVQAEIKKSW----NRRTLALDFKRKARSGS 442          

Query:  124 IEHDSQETLLRKAQENCNSKISNFSIAKLSLNTSFCRPVWDGVVCWYGYFQSGKTASQPCPHYIDKFIRKGKVYKRCTVNGEWFRRANSTKPWTDFGECKQ--STN----KEPALFFVVTISNIGFFISITSVLLGIFILRFFKNLHCDRNTIHINLFVACLLRSCFSLF--------------SQLQTNNETNTFCKVFMSMHNYLIMANFTWVFVEALYLHNVLTLHTFKETSGVVFLYILVGWGXXXXXXXXXXXXXXVFDNTYCWDAGDSQITLDMWVLFVYPVLLLIQNIIFFIKLIVILHAKMV---THQLTASQNKFRKLARSILVLMVVFGIYQLIFVPLDLIENMHNNKVTFQIKMCAEHLINSAQGFLLAMMFCFCNSEVLKEIKRKFENHRNSRSLQTTDEVKI 1299
            I  D Q  +L  AQ  C   I   +     +    C P WDG++CW    ++G+  S PCP YI  F  +G+ Y++C V G W    ++   W ++ EC +  ++N    +E     +  +  +G+ IS++S+L+ + IL +FK LHC RN IHI+LF + + R+  S+F              ++     +    CK  ++   Y +  N  W+  E LYLH+++ +    + + +  L I+ GWG+P + + +W+  R    +T CWD     +    W+  V  +  +  N + FI +I +L +K+    T +L   Q ++RKL RS LVLM +FG++ ++F+ +   E    N + +Q++M  E   NS+QGF +A ++CFCN EV  E+K+ +   R S +L    + +I
Sbjct:   29 ITRDEQIYVLTGAQARCERSIQTQTAI---IKEGDCVPEWDGIICW-PQSRAGQLVSVPCPEYIYDFNHRGRAYRQCDVTGNWELVTSNNHTWANYTECTRYLTSNHRSLQEKVFKRLHLMYTVGYSISLSSLLVAVSILCYFKRLHCTRNYIHIHLFTSFICRA-VSIFVKDSVLYSITDDSKAEFPAERQYTAGCKAAVTFFLYFLATNHYWILAEGLYLHSLIFMALLSDKNYLWVLTIM-GWGIPAVFVSVWVSARASLADTQCWDISAGNLK---WIYQVPILAGIFVNFLLFINIIRVLASKLWETNTGKLNPRQ-QYRKLLRSTLVLMPLFGVHYIVFMAIPYTE---VNGLLWQVQMHYEMFFNSSQGFFVAFIYCFCNGEVQAEVKKAWL--RRSLTLDLKQKARI 428          

Query:   37 AMRLFVWILLTFIWCPFLQGKSIRKLEYKIEHDSQETLLRKAQENCNSKISNFSIAKLSLNTSFCRPVWDGVVCWYGYFQSGKTASQPCPHYIDKFIRKGKVYKRCTVNGEWFRRANSTKPWTDFGEC-------KQSTNKEPALFFVVTISNIGFFISITSVLLGIFILRFFKNLHCDRNTIHINLFVACLLRSCFSLF----------------SQLQTNNETNTF----------CKVFMSMHNYLIMANFTWVFVEALYLHNVLTLHTFKETSGVVFLYILVGWGXXXXXXXXXXXXXXVFDNTYCWDAGDSQITLDMWVLFVYPVLLLIQ-NIIFFIKLIVILHAKM--VTHQLTASQNKFRKLARSILVLMVVFGIYQLIFVPLDLIENMHN-NKVTFQIKMCAEHLINSAQGFLLAMMFCFCNSEVLKEIKRKF 1248
            +     WIL  F++  ++  +     +  +    Q  +L + +  C     N S  + +     C P WDG++CW  +   G+    PCP YI  F  KG  Y++C VNG W       K WT++ EC       K    ++     +  +   G+ +S +S+L+ I I+ +F+ LHC RN IH++LFV+ +LR+  S+F                S L  N +T +           CK+ + +  Y +  N+ W+ VE LYLH+++ +  F+  S  ++ +I +GWG+P + + IW I+R    +  CW+     +    W+  V P+L  I  N I F+ ++ +L  K+         ++ ++RKLA+S LVL++VFGI+ +IFV +      H     +++++M  E   NS QGF +++++C+CN EV  EIK+ +
Sbjct:   15 SANFLTWILNFFLYWQWIDAQ--MGFDGPLSAQEQMLILYEVKIQC---YQNLSSMEPTTTDEVCPPDWDGLICW-PHGSPGQVTEVPCPSYIYDFNHKGHAYRKCDVNGSWVFVEQWNKTWTNYSECLSFLQPFKDEEARQDFFERLYVMYTTGYAVSFSSLLVAIMIIGYFRRLHCTRNYIHMHLFVSFMLRAV-SIFVKDKVVYSSAGLQDFDSALLDNLKTVSIASVDKSHYIGCKMTVVLFIYFLATNYYWILVEGLYLHSLIFM-AFRSDSKYLWGFIFIGWGVPAVFVAIWAIVRATLADARCWELSAGNVK---WIYQV-PILTAIGLNFILFVNIVRVLATKIRETNAGRYDTRKQYRKLAKSTLVLVLVFGIHYIIFVGMP-----HTFQGPSWEMRMYFELFFNSFQGFFVSIIYCYCNGEVQTEIKKTW 438          

Query:  151 LRKAQENCNSKISNFSIAKLSLNTSFCRPVWDGVVCWYGYFQSGKTASQPCPHYIDKF---IRKGKVYKRCTVNGEWFRRANSTKPWTDFGECKQSTNKEPALFFVVTISNIGFFISITSVLLGIFILRFFKNLHCDRNTIHINLFVACLLRSC------FSLFSQLQTNN-ETNTFCKVFMSMHNYLIMANFTWVFVEALYLHNVLTLHTFKETSGVVFLYILVGWGXXXXXXXXXXXXXXVFDNTYCWDAGDSQITLDMWVLFVYPVLLLIQNIIFFIKLIVILHAKMVTHQLTASQ-NKFRKLARSILVLMVVFGIYQLIFVPLDLIENMHNNKVTFQIKMCAEHLINSAQGFLLAMMFCFCNSEVLKEIKRKFENHRNSRSLQTTDEVKIRENSYRKRRGNRDSLKQT 1353
            + K +  C ++I N         T+ C   WD + CW G  + G+  + PCP Y+  F   +    V K CT NG    R +  +      EC  + N       V+  + +G  +S+ S+++ I IL  F+ LHC RN IH++LFV+ +L++         L+   +T+N + +  CK  + + +Y +MA++ W+ VE LYLH +L +  F E     + YI++GWG+P I I  W+I +   D+  CW+  D  +    W++ +   L ++ N + FI +I IL  KM    +   + N++ +LA+S L+L+ +FGI  ++F  +   ENMH      Q++M  + ++ S QGF++A+++CF N EV  EIKRK+      R L T  + K ++ S     GN  S + T
Sbjct:   19 IEKERSICEAQIEN--------KTTSCSVEWDNITCWPGA-EIGEVVTIPCPKYLFYFSEDMPPRNVSKTCTANGLTPIRVDYVR------ECGYNPNNTVEENSVMGYT-VGHSVSLISLMIAISILCLFRKLHCTRNYIHMHLFVSLILKAVTVFIKDVVLYDVGETDNCQGSVGCKAVVVIFHYGVMASYFWLLVEGLYLHALLAVSFFSERK-YFWWYIVIGWGVPTIFICAWVITKAYLDHPGCWETIDDNL---WWIIRIPISLSILVNFLLFICIIRILLQKMNCPDIGRRESNQYSRLAKSTLLLIPLFGINYILFAYIP--ENMH-----VQVRMVFDLVLGSFQGFVVAILYCFLNGEVQSEIKRKWRRWMLQRFLGT--DAKYQQPS-MGSNGNNSSTQIT 400          

Query:  151 LRKAQENCNSKISNFSIAKLSLNTSFCRPVWDGVVCWYGYFQSGKTASQPCPHYIDKF---IRKGKVYKRCTVNGEWFRRANSTKPWTDFGECKQSTNKEPALFFVVTISNIGFFISITSVLLGIFILRFFKNLHCDRNTIHINLFVACLLRSC------FSLFSQLQTNN-ETNTFCKVFMSMHNYLIMANFTWVFVEALYLHNVLTLHTFKETSGVVFLYILVGWGXXXXXXXXXXXXXXVFDNTYCWDAGDSQITLDMWVLFVYPVLLLIQNIIFFIKLIVILHAKMVTHQLTASQ-NKFRKLARSILVLMVVFGIYQLIFVPLDLIENMHNNKVTFQIKMCAEHLINSAQGFLLAMMFCFCNSEVLKEIKRKFENHRNSRSLQTTDEVKIRENSYRKRRGNRDSLKQT 1353
            + K +  C ++I N         T+ C   WD + CW G  + G+  + PCP Y+  F   +    V K CT NG    R +  +      EC  + N       V+  + +G  +S+ S+++ I IL  F+ LHC RN IH++LFV+ +L++         L+   +T+N + +  CK  + + +Y +MA++ W+ VE LYLH +L +  F E     + YI++GWG         I L   F    CW+  D  +    W++ +   L ++ N + FI +I IL  KM    +   + N++ +LA+S L+L+ +FGI  ++F  +   ENMH      Q++M  + ++ S QGF++A+++CF N EV  EIKRK+      R L T  + K ++ S     GN  S + T
Sbjct:   19 IEKERSICEAQIEN--------KTTSCSVEWDNITCWPGA-EIGEVVTIPCPKYLFYFSEDMPPRNVSKTCTANGLTPIRVDYVR------ECGYNPNNTVEENSVMGYT-VGHSVSLISLMIAISILCLFRKLHCTRNYIHMHLFVSLILKAVTVFIKDVVLYDVGETDNCQGSVGCKAVVVIFHYGVMASYFWLLVEGLYLHALLAVSFFSERK-YFWWYIVIGWG-------KCIELFSCFYCFRCWETIDDNL---WWIIRIPISLSILVNFLLFICIIRILLQKMNCPDIGRRESNQYSRLAKSTLLLIPLFGINYILFAYIP--ENMH-----VQVRMVFDLVLGSFQGFVVAILYCFLNGEVQSEIKRKWRRWMLQRFLGT--DAKYQQPS-MGSNGNNSSTQIT 393          

Query:   40 MRLFVWILLTFIWCPFLQGKSIRKLEYKIEHDSQETLLRKAQENCNSKISNFSIAKLSLNTSFCRPVWDGVVCWYGYFQSGKTASQPCPHYIDKFIRKGKVYKRCTVNGEWFRRANSTKPWTDFGECKQSTNKEPALFFVVTISNIGFFISITSVLLGIFILRFFKNLHCDRNTIHINLFVACLLRSCFSLFSQLQTNNETNTFCKVFMSMHNYLIMANFTWVFVEALYLHNVLTLHTFKETSGVVFLYILVGWGXXXXXXXXXXXXXXVFDNTYCWDAGDSQITLDMWVLFVYPVLLLIQNIIFFIKLIVILHAKMVTHQLTASQNKFRKLARSILVLMVVFGIYQLIFVPLDLIENMHNNKVTFQIKMCAEHLINSAQGFLLAMMFCFCNSEVLKEIKRKFENHRNSRSLQTTDEVKIRENSYRKRRGNRDSLKQTDHQVTCQFSVSE 1389
            MRLFVWILLTFIWCPFLQGKSIRKLEYKIEHDSQETLLRKAQENCNSKISNFSIAKLSLNTSFCRPVWDGVVCWYGYFQSGKTASQPCPHYIDKFIRKGKVYKRCTVNGEWFRRANSTKPWTDFGECKQSTNKEPALFFVVTISNIGFFISITSVLLGIFILRFFKNLHCDRNTIHINLFVACLLRSCFSLFSQLQTNNETNTFCKVFMSMHNYLIMANFTWVFVEALYLHNVLTLHTFKETSGVVFLYILVGWGLPLIAIIIWIILRLVFDNTYCWDAGDSQITLDMWVLFVYPVLLLIQNIIFFIKLIVILHAKMVTHQLTASQNKFRKLARSILVLMVVFGIYQLIFVPLDLIENMHNNKVTFQIKMCAEHLINSAQGFLLAMMFCFCNSEVLKEIKRKFENHRNSRSLQTTDEVKIRENSYRKRRGNRDSLKQTDHQVTCQFSVSE
Sbjct:    1 MRLFVWILLTFIWCPFLQGKSIRKLEYKIEHDSQETLLRKAQENCNSKISNFSIAKLSLNTSFCRPVWDGVVCWYGYFQSGKTASQPCPHYIDKFIRKGKVYKRCTVNGEWFRRANSTKPWTDFGECKQSTNKEPALFFVVTISNIGFFISITSVLLGIFILRFFKNLHCDRNTIHINLFVACLLRSCFSLFSQLQTNNETNTFCKVFMSMHNYLIMANFTWVFVEALYLHNVLTLHTFKETSGVVFLYILVGWGLPLIAIIIWIILRLVFDNTYCWDAGDSQITLDMWVLFVYPVLLLIQNIIFFIKLIVILHAKMVTHQLTASQNKFRKLARSILVLMVVFGIYQLIFVPLDLIENMHNNKVTFQIKMCAEHLINSAQGFLLAMMFCFCNSEVLKEIKRKFENHRNSRSLQTTDEVKIRENSYRKRRGNRDSLKQTDHQVTCQFSVSE 450          

Query:  118 YKIEHDSQETLLRKAQENCNSKIS--NFSIAKLSLNTSFCRPVWDGVVCWYGYFQSGKTASQPCPHYIDKFIRKGKVYKRCTVNGEWFRRANSTKPWTDFGECKQSTNKEPALFF--VVTISNIGFFISITSVLLGIFILRFFKNLHCDRNTIHINLFVACLLRSCFS-LFSQLQTNNETNTFCKVFMSMHNYLIMANFTWVFVEALYLHNVLTLHTFKETSGVVFLYILVGWGXXXXXXXXXXXXXXVFDNTYCWDAGDSQITLDMWVLFVYPVLLLIQNIIFFIKLIVILHAKMVTHQLTASQNKFRKLARSILVLMVVFGIYQLIFVPLDLIENMHNN---KVTFQIKMCAEHLINSAQGFLLAMMFCFCNSEVLKEIKRKFENHRNSRSLQTTDEVKIRENSYRKRRG 1329
            Y+I  D Q   + +    C  ++S  N+S+  +++N+  C   WDG++CW    ++GK  S  CP+Y+D F   G V K+CT NG W+ + N T  WT++ +CK   +      F  +  I  +G+ ISI S+++ I IL  F+ L C+RN IH+NLF A   R+ F  L S LQT      +C+    ++NY   A+F  +F EA+Y+HN++  HTF  +     +YI++ W +P   I IW +LR  F+N YCWD  + +   D W L  Y +LL + N + FI L   L +KM +H ++  + KF+KLARSI +L++VFG+Y ++FVP+++I  + +N   K T  IK+   H+ NS QGFL++++ CF NSEV +EIKR  +    SR  Q ++      N+ R RR 
Sbjct:   12 YQIPQDKQMESIIEEHIKCLGRMSFLNYSLDIVTINSK-CPVSWDGIMCW-PETEAGKLVSSRCPNYVDSFQINGTVTKKCTNNGTWYLKDNVT--WTNYSDCKSKIDSLAFKQFEKIEKIGQVGYAISILSLVIAIIILCSFRRLRCNRNYIHLNLFFAFFFRAIFHYLTSFLQTEK---IYCRALRVIYNYFTQASFQSIFTEAIYMHNMIFYHTFDSSKINTPVYIVLCWVVPGFVIGIWSLLRYKFNNVYCWDLSNDKHNRDFWFLNAYVILLTLVNSVIFIILTCSLCSKMNSH-ISTEREKFKKLARSICILVIVFGVYNVVFVPVEIICAIADNATAKKTELIKLYFHHIFNSCQGFLVSLLLCFVNSEVHREIKRFIQKILISRGFQNSNIYVF--NNIRSRRS 413          

Query:  118 YKIEHDSQETLLRKAQENCNSKIS--NFSIAKLSLNTSFCRPVWDGVVCWYGYFQSGKTASQPCPHYIDKFIRKGKVYKRCTVNGEWFRRANSTKPWTDFGECKQSTNKEPALFF--VVTISNIGFFISITSVLLGIFILRFFKNLHCDRNTIHINLFVACLLRSCFS-LFSQLQTNNETNTFCKVFMSMHNYLIMANFTWVFVEALYLHNVLTLHTFKETSGVVFLYILVGWGXXXXXXXXXXXXXXVFDNTYCWDAGDSQITLDMWVLFVYPVLLLIQNIIFFIKLIVILHAKMVTHQLTASQNKFRKLARSILVLMVVFGIYQLIFVPLDLIENMHNN---KVTFQIKMCAEHLINSAQGFLLAMMFCFCNSEVLKEIKRKFENHRNSRSLQTTDEVKIRENSYRKRRG 1329
            Y+I  D Q   + +    C  ++S  N+S+  +++N+  C   WDG++CW    ++GK  S  CP+Y+D F   G V K+CT NG W+ + N T  WT++ +CK   +      F  +  I  +G+ ISI S+++ I IL  F+ L C+RN IH+NLF A   R+ F  L S LQT      +C+    ++NY   A+F  +F EA+Y+HN++  HTF  +     +YI++ W +P   I IW +LR  F+N YCWD  + +   D W L  Y +LL + N + FI L   L +KM +H ++  + KF+KLARSI +L++VFG+Y ++FVP+++I  + +N   K T  IK+   H+ NS QGFL++++ CF NSEV +EIKR  +    SR  Q ++      N+ R RR 
Sbjct:   22 YQIPQDKQMESIIEEHIKCLGRMSFLNYSLDIVTINSK-CPVSWDGIMCW-PETEAGKLVSSRCPNYVDSFQINGTVTKKCTNNGTWYLKDNVT--WTNYSDCKSKIDSLAFKQFEKIEKIGQVGYAISILSLVIAIIILCSFRRLRCNRNYIHLNLFFAFFFRAIFHYLTSFLQTEK---IYCRALRVIYNYFTQASFQSIFTEAIYMHNMIFYHTFDSSKINTPVYIVLCWVVPGFVIGIWSLLRYKFNNVYCWDLSNDKHNRDFWFLNAYVILLTLVNSVIFIILTCSLCSKMNSH-ISTEREKFKKLARSICILVIVFGVYNVVFVPVEIICAIADNATAKKTELIKLYFHHIFNSCQGFLVSLLLCFVNSEVHREIKRFIQKILISRGFQNSNIYVF--NNIRSRRS 423          

Query:  118 YKIEHDSQETLLRKAQENCNSKIS--NFSIAKLSLNTSFCRPVWDGVVCWYGYFQSGKTASQPCPHYIDKFIRKGKVYKRCTVNGEWFRRANSTKPWTDFGECKQSTNKEPALFF--VVTISNIGFFISITSVLLGIFILRFFKNLHCDRNTIHINLFVACLLRSCFS-LFSQLQTNNETNTFCKVFMSMHNYLIMANFTWVFVEALYLHNVLTLHTFKETSGVVFLYILVGWGXXXXXXXXXXXXXXVFDNTYCWDAGDSQITLDMWVLFVYPVLLLIQNIIFFIKLIVILHAKMVTHQLTASQNKFRKLARSILVLMVVFGIYQLIFVPLDLIENMHNN---KVTFQIKMCAEHLINSAQGFLLAMMFCFCNSEVLKEIKRKFENHRNSRSLQTTDEVKIRENSYRKRRG 1329
            Y+I  D Q   + +    C  ++S  N+S+  +++N+  C   WDG++CW    ++GK  S  CP+Y+D F   G V K+CT NG W+ + N T  WT++ +CK   +      F  +  I  +G+ ISI S+++ I IL  F+ L C+RN IH+NLF A   R+ F  L S LQT      +C+    ++NY   A+F  +F EA+Y+HN++  HTF  +     +YI++ W +P   I IW +LR  F+N YCWD  + +   D W L  Y +LL + N + FI L   L +KM +H ++  + KF+KLARSI +L++VFG+Y ++FVP+++I  + +N   K T  IK+   H+ NS QGFL++++ CF NSEV +EIKR  +    SR  Q ++      N+ R RR 
Sbjct:   23 YQIPQDKQMESIIEEHIKCLGRMSFLNYSLDIVTINSK-CPVSWDGIMCW-PETEAGKLVSSRCPNYVDSFQINGTVTKKCTNNGTWYLKDNVT--WTNYSDCKSKIDSLAFKQFEKIEKIGQVGYAISILSLVIAIIILCSFRRLRCNRNYIHLNLFFAFFFRAIFHYLTSFLQTEK---IYCRALRVIYNYFTQASFQSIFTEAIYMHNMIFYHTFDSSKINTPVYIVLCWVVPGFVIGIWSLLRYKFNNVYCWDLSNDKHNRDFWFLNAYVILLTLVNSVIFIILTCSLCSKMNSH-ISTEREKFKKLARSICILVIVFGVYNVVFVPVEIICAIADNATAKKTELIKLYFHHIFNSCQGFLVSLLLCFVNSEVHREIKRFIQKILISRGFQNSNIYVF--NNIRSRRS 424          

Query:  118 YKIEHDSQETLLRKAQENCNSKIS--NFSIAKLSLNTSFCRPVWDGVVCWYGYFQSGKTASQPCPHYIDKFIRKGKVYKRCTVNGEWFRRANSTKPWTDFGECKQSTNKEPALFF--VVTISNIGFFISITSVLLGIFILRFFKNLHCDRNTIHINLFVACLLRSCFS-LFSQLQTNNETNTFCKVFMSMHNYLIMANFTWVFVEALYLHNVLTLHTFKETSGVVFLYILVGWGXXXXXXXXXXXXXXVFDNTYCWDAGDSQITLDMWVLFVYPVLLLIQNIIFFIKLIVILHAKMVTHQLTASQNKFRKLARSILVLMVVFGIYQLIFVPLDLIENMHNN---KVTFQIKMCAEHLINSAQGFLLAMMFCFCNSEVLKEIKRKFENHRNSRSLQTTDEVKIRENSYRKRRG 1329
            Y+I  D Q   + +    C  ++S  N+S+  +++N+  C   WDG++CW    ++GK  S  CP+Y+D F   G V K+CT NG W+ + N T  WT++ +CK   +      F  +  I  +G+ ISI S+++ I IL  F+ L C+RN IH+NLF A   R+ F  L S LQT      +C+    ++NY   A+F  +F EA+Y+HN++  HTF  +     +YI++ W +P   I IW +LR  F+N YCWD  + +   D W L  Y +LL + N + FI L   L +KM +H ++  + KF+KLARSI +L++VFG+Y ++FVP+++I  + +N   K T  IK+   H+ NS QGFL++++ CF NSEV +EIKR  +    SR  Q ++      N+ R RR 
Sbjct:   31 YQIPQDKQMESIIEEHIKCLGRMSFLNYSLDIVTINSK-CPVSWDGIMCW-PETEAGKLVSSRCPNYVDSFQINGTVTKKCTNNGTWYLKDNVT--WTNYSDCKSKIDSLAFKQFEKIEKIGQVGYAISILSLVIAIIILCSFRRLRCNRNYIHLNLFFAFFFRAIFHYLTSFLQTEK---IYCRALRVIYNYFTQASFQSIFTEAIYMHNMIFYHTFDSSKINTPVYIVLCWVVPGFVIGIWSLLRYKFNNVYCWDLSNDKHNRDFWFLNAYVILLTLVNSVIFIILTCSLCSKMNSH-ISTEREKFKKLARSICILVIVFGVYNVVFVPVEIICAIADNATAKKTELIKLYFHHIFNSCQGFLVSLLLCFVNSEVHREIKRFIQKILISRGFQNSNIYVF--NNIRSRRS 432