WD repeat-containing protein on Y chromosome

Query:  419 IEERIDLTVLEELKAAFENAEYDRSGKLDLSEFKALLKEKLQLPTFEDIQTETLFKKIDWASSGAINWDEFCTYMQLEYAEKEETYLKAREMAFCLPA--RIENTP--HRENVIRITSTSDGS-FIAGSTDGILSFWSNTLELKKCKSVVTIEQSQRVKSKWIIDFLIMNEFNKIIVATGDREIEFFELSSFEPYC---RIHSLENVPLCLDYYVDKDNLDDCLILWGDRKGCVNILHLHATGECLRTWKKQPRS-----EGIAGIGMENVLS--NPSIKFYRWKVH-NDWVLKLKYYDSLRQIISCSNDEATALVIGCVEGSTQLDQQMKLKSMHQTKSKDMTFGNMLQPKRRISTDQTVFNIYKGIQTFDFGKSKNVLVTGGLDRIIRLWNPYVNSKPTGMLRGHNKPLVYVHIAEQENRIFSICADKCVKVWDLHDHNCLLTVRPKGHRIRGDMQSCHYSDFAKSLMIATDQVSMLNIKINPFVAEKQLDERHQRASYLGGCYFEQISQNTVLVNKPPVLHTDVAVTHKDPVTCCKYNEAFNQVVTCCEGSTVKLWNLSTGEKVFEFNEAHEDSGVTCLTFDSXXXXXXXXXXDGMVRMWNFNNGHCLTELKKEESDLKYAEISAVEYVEI-SRNKFIVSVGWDRAINVYIDQCEPGMHKSYYPQSRWLDDMSNGHKEDILTLATLKGHLLATADYHGTIIVWNLM---SGHVFF----------------KLIS--------PVAXXXXXXXX-----XXXXXSINKLLFLQSRAKNK--SSASLVASGPYGLVHFWNVKEGGILYGRFKGGTESGQSLTAMIACKDQDIDDKLLFIGDRFGFISVWDIENY----ANNKVETDCPELLRRWRAHVSSITSLDLVLQSQ--VLITSSDDCTVRVWTFEGEYVGTFGQTEMWDLTN 3034
            +E ++ +    +++ AFE+ +  +   +   +F   + E +   T E+     LF K+D A  G INWD+  +++ LE  E++E     R  A  +P    +E  P  H++ + ++    + S ++  S +G+L+ W   L+L++   + +   + ++K  W+   + +   NKI VA   +E+ F++L S E +    ++  L+  P+C+DY+ D  + ++ ++ +GD  G V  +   A    L +  ++P S     E    I    +LS  +        K+H  DWV ++ Y  SL  IIS +     ++V+   E S                            K+R+  + T FNI +GI  FD+    N++ T G++  + LWNPYV SKP G+L GH+  ++ V    +  ++FS   DK +++WD+             H++     +C +                   K   F      DE H      G  +    +Q  +L  K     +    +H+  VTC  YN    QV++   GSTV  W + TG+K+ +F   H ++ ++ +  D+   RLLTG  DG V++W+F NG+C          L   +  AV+  +I    K I+  GW+RAI V+  Q     ++ +     W   +   H +DIL  A L    L T  Y G I++WN     + HV                  KL+S        P+AD             +   ++ +L FL++R        A+LV+ G  G V FW++ +  +L   F   +  G  + +       D  ++ L  GD  G++ +W+IE Y    + NK+ T  P L+R ++ H   I+SL++       ++I+SS DC++ V       V  FGQ + W + N
Sbjct:   38 LENQLSVGDFVKIQKAFESPQPRKIICMSREDFTQKMTEIVGWGTKEEYGE--LFDKVDVAQDGFINWDKLTSFILLELYEQDE-----RAKATVVPQWKDLEFLPVKHKDTIQKVIFLKNSSHYLTISKEGLLAIWGEHLKLQETFPITS--DATKLKHLWVTSLVSLENVNKIAVAFTSKEVCFYDLLSKEEFACQYKLQGLKGTPICMDYWYDPLDANESILSFGDITGKVQAIAFTAA---LISLFERPASACEDGEATMTINWAELLSGCHKCCHILEHKLHQGDWVRQVTYNASLDAIISSTTSNTNSVVMAWREKS----------------------------KKRL--NMTSFNIAQGIHAFDYHSRLNLIATAGINNKVCLWNPYVVSKPVGVLWGHSASVIAVQFFVERKQLFSFSKDKVLRLWDIQ------------HQLSIQRIACSFP------------------KSQDFRCLFHFDEAH------GRLFISFNNQLALLAMKSEA--SKRVKSHEKAVTCVLYNSILKQVISSDTGSTVSFWMIDTGQKIKQFTGCHGNAEISTMALDANETRLLTGSTDGTVKIWDF-NGYC-------HHTLNVGQDGAVDISQILILKKKILVTGWERAITVFRPQ---NFNQFFIQPEEWKGGIQ--HHDDILCAAFLPPQTLVTGSYDGEIVLWNNSTENAHHVLHPDYQRLLKSKLDTKPQKLLSAGRSQPSHPMADHSTTGVRNFEIDTEGKNAVMRLCFLKARKNTAVTGGANLVSCGGSGYVRFWDIYKKQLL-AEFLAHSGVGSIIMST------DKMNRYLTTGDLDGWLKIWNIEEYCLNSSKNKI-TKAPTLIRSFQPHEDRISSLEMCEPGGQLLIISSSADCSICVTGVCNAPVWIFGQAKHWHIEN 865          

Query:  446 LEELKAAFENAEYDRSGKLDLSEFKALLKEKLQLPTFEDIQTETLFKKIDWASSGAINWDEFCTYMQLEYAEKEETYLKAREMAFCLPARIENTPHRENVIRIT-----STSDGSFIAGSTDGILSFWSNTLELKKCKSVVTIEQSQRVKSK--WIIDFLIMNEFNKIIVATGDREIEFFELSSFEPYC----RIHSLENVPLCLDYYVDKDNLDDCLILWGDRKGCVNILHLHATGECLRTWKKQPRS---EGIAGIGMENVLSNPSI--KFYRWK-VHNDWVLKLKYYDSLRQIISCSNDEATALVIGCVEGSTQLDQQMKLKSMHQTKSKDMTFGNMLQPKRRISTDQTVFNIYKGIQTFDFGKSKNVLVTGGLDRIIRLWNPYVNSKPTGMLRGHNKPLVYVHIAEQENRIF-SICADKCVKVWDLHDHNCLLTVRPKGHRIRG-DMQSCHYSDFAKSLMIATDQVSMLNIKINPFVAEKQLDERHQRASYLGGCYFEQISQNTVLVNKPPVLHTDVAVTHKDPVTCCKYNEAFNQVVTCCEGSTVKLWNLSTGEKVFEFN-EAHEDSGVTCLTFDSXXXXXXXXXXDGMVRMWNFNNGHCLTELKKEESDLKYAEISAVEYVEISRNKFIVSVGWDRAINVYIDQCEPGMHKSYYPQSRWLDDMSNGHKEDILTLATLKGHLLATADYHGTIIVWN 2488
            L +++  FE  + + +G L +  F   +K+ L   +  D   + LF K+D    G + W ++  YM  E+  KE+       + F LP  +    H   V+++          G F+  + DGIL FWS +  L    S   + Q+Q++ ++  W+ID + ++  N + VA+  ++I+FF++S  +  C        L++  L +DY+ D      C   +GD KG V +         L   +  PR+   +    + ++ +L+  S   + YR K +H +W  ++K+   +  ++SCS  E ++LV+  +                               K R+S    V  + KGI  FD+   +N LVTGG D  IRLWNP+V+ +P  +++GH   + ++ +  + N I  S+  DK ++VWD+ D+ CL +   K   +    + S ++ +   +L+ +T  + +L                          Y E  +Q  +   K          TH  P+    Y++ F QVV+ C   TV +W + TG K  EF     +   +T +  D + R LLTG RDG ++MWN+N G CL      E      EIS +    I  NK     GW + I  ++      +   Y+ Q+         H EDIL++A  +   L T+ Y G I+ WN
Sbjct:   54 LAKIEKMFEE-DINSTGALGMDAFIKAMKKVLS--SVSDEMLKELFLKVDSDCEGFVTWQKYVDYMMREFQGKEDMRKSQYRLHFYLPMTVVPLNHGCEVVKVVFLIHRFKKIGCFLTVTKDGILQFWSESFSL---MSSFRLNQTQQLYNQPMWVIDMVCLHNMNLVAVASTRQKIDFFDISDHK--CVRAFTFVDLDSCALVMDYWSDYHRGVFC---YGDAKGNVIVFTSENMTSGLFNPRILPRASKWDHWIKVSLQKLLNEKSALHRSYRLKALHPNWCEQVKFIPQMNVVVSCSAIEKSSLVLTILPAKA-------------------------SKKPRLS----VLRLRKGILCFDYCPDRNFLVTGGYDAFIRLWNPFVSKRPVWLMKGHQTSVTHILVDSRNNSILISVSKDKNIRVWDMLDYICLQSFCGKFFALGNCPITSAYFFEKDNTLICSTYSIGILK------------------------GYLE--AQGLIKARK--------RTTHCSPLCAVLYSKIFKQVVSGCLRGTVSVWEVVTGRKTMEFAVSGGQHVEMTAMALDESERCLLTGLRDGTMKMWNYNIGKCLLTFPSPEQ----LEISGI----IHMNKVFYVTGWSKRITHFLFHKTKPVLLCYHWQTY--------HTEDILSMAKYRNQFLGTSSYSGDILFWN 664          

Query: 2573 SINKLLFLQSRAKNKSSASLVASGPYGLVHFWNVKEGGILYGRFKGGTESGQSLTAMIACKDQDIDDKLLFIGDRFGFISVWDIENY-------------------ANNKVETDCPE-----------------------------LLRRWRAHVSSITSLDLVLQSQVLITSSDDCTVRVWTFEGEYVGTFG 3007
            S+ K++FLQ+R +   +A+L++S   G ++ W++ E G L G+F    ++G  +   +A    D +D +L  GD  G+I +WDI++Y                   A+NK     P+                             LL  W+ H++S+  +  V   Q++I++  D  V+ W   G+ +GTFG
Sbjct:  801 SVEKIIFLQTRPRLPHTAALLSSCMDGYIYAWSLHENGGLLGKFPVDLDNGDVVVGAMAT---DKNDWILITGDCKGYIKIWDIKDYCALIDKQPFQSSGAKVVSEAHNKFRLLIPQQLGTNFPHYIPLEDKEVVAGHTISLVPPTLLMTWKGHLNSVADILYVDNFQLVISAGQDRDVKAWKLSGDAIGTFG 990          

Query: 1418 QPKRRISTDQTVFNIYKGIQTFDFGKSKNVLVTGGLDRIIRLWNPYVNSKPTGMLRGHNKPLVYVHIAEQENRIFSICADKCVKVWDLHDHNCLLTVRPKGHRIRGDMQSCHYSDFAKSLMIATDQVSMLNIKINPFVAEKQLDERHQRASYLGGCYFEQISQNTVLVNKPPVLHTDVAVTHKDPVTCCKYNEAFNQVVTCCEGSTVKLWNLSTGEKVFEFNEAHEDSGVTCLTFDSXXXXXXXXXXDGMVRMWNFNNGHCLTELKKEESDLKYAEISAVEYVEI-SRNKFIVSVGWDRAINVYIDQCEPGMHKSYYPQSRWLDDMSNGHKEDILTLATLKGHLLATADYHGTIIVWNLM---SGHVFF----------------KLIS--------PVAXXXXXXXX-----XXXXXSINKLLFLQSRAKNK--SSASLVASGPYGLVHFWNVKEGGILYGRFKGGTESGQSLTAMIACKDQDIDDKLLFIGDRFGFISVWDIENY----ANNKVETDCPELLRRWRAHVSSITSLDLVLQSQ--VLITSSDDCTVRVWTFEGEYVGTFGQTEMWDLTN 3034
            + K+R+  + T FNI +GI  FD+    N++ T G++  + LWNPYV SKP G+L GH+  ++ V    +  ++FS   DK +++WD+             H++     +C +                   K   F      DE H      G  +    +Q  +L  K     +    +H+  VTC  YN    QV++   GSTV  W + TG+K+ +F   H ++ ++ +  D+   RLLTG  DG V++W+F NG+C          L   +  AV+  +I    K I+  GW+RAI V+  Q     ++ +     W   +   H +DIL  A L    L T  Y G I++WN     + HV                  KL+S        P+AD             +   ++ +L FL++R        A+LV+ G  G V FW++ +  +L   F   +  G  + +       D  ++ L  GD  G++ +W+IE Y    + NK+ T  P L+R ++ H   I+SL++       ++I+SS DC++ V       V  FGQ + W + N
Sbjct:    6 KSKKRL--NMTSFNIAQGIHAFDYHSRLNLIATAGINNKVCLWNPYVVSKPVGVLWGHSASVIAVQFFVERKQLFSFSKDKVLRLWDIQ------------HQLSIQRIACSFP------------------KSQDFRCLFHFDEAH------GRLFISFNNQLALLAMKSEA--SKRVKSHEKAVTCVLYNSILKQVISSDTGSTVSFWMIDTGQKIKQFTGCHGNAEISTMALDANETRLLTGSTDGTVKIWDF-NGYC-------HHTLNVGQDGAVDISQILILKKKILVTGWERAITVFRPQ---NFNQFFIQPEEWKGGIQ--HHDDILCAAFLPPQTLVTGSYDGEIVLWNNSTENAHHVLHPDYQRLLKSKLDTKPQKLLSAGRSQPSHPMADHSTTGVRNFEIDTEGKNAVMRLCFLKARKNTAVTGGANLVSCGGSGYVRFWDIYKKQLL-AEFLAHSGVGSIIMST------DKMNRYLTTGDLDGWLKIWNIEEYCLNSSKNKI-TKAPTLIRSFQPHEDRISSLEMCEPGGQLLIISSSADCSICVTGVCNAPVWIFGQAKHWHIEN 524          

Query:  926 IIVATGDREIEFFELSSFEPYC---RIHSLENVPLCLDYYVDKDNLDDCLILWGDRKGCVNILHLHATGECLRTWKKQPRS-----EGIAGIGMENVLS--NPSIKFYRWKVHN-DWVLKLKYYDSLRQIISCSNDEATALVIGCVEGSTQLDQQMKLKSMHQTKSKDMTFGNMLQPKRRISTDQTVFNIYKGIQTFDFGKSKNVLVTGGLDRIIRLWNPYVNSKPTGMLRGHNKPLVYVHIAEQENRIFSICADKCVKVWDLHDHNCLLTVRPKGHRIRGDMQSCHYSDFAKSLMIATDQVSMLNIKINPFVAEKQLDERHQRASYLGGCYFEQISQNTVLVNKPPVLHTDVAVTHKDPVTCCKYNEAFNQVVTCCEGSTVKLWNLSTGEKVFEFNEAHEDSGVTCLTFDSXXXXXXXXXXDGMVRMWNFNNGHCLTELKKEESDLKYAEISAVEYVEI-SRNKFIVSVGWD-----------RAINVYIDQCEPGMHKSYYPQSRWLDDMSNGHKEDILTLATLKGHLLATADYHGTIIVWNLM---SGHVFF----------------KLIS--------PVAXXXXXXXX-----XXXXXSINKLLFLQSRAKNK--SSASLVASGPYGLVHFWNVKEGGILYGRFKGGTESGQSLTAMIACKDQDIDDKLLFIGDRFGFISVWDIE 2827
            I VA   +E+ F++L S E +    ++  L+  P+C+DY+ D  + ++ ++ +GD  G V  +   A    L +  ++P S     E    I    +LS  +        K+H  DWV ++ Y  SL  IIS +     ++V+   E S                            K+R+  + T FNI +GI  FD+    N++ T G++  + LWNPYV SKP G+L GH+  ++ V    +  ++FS   DK +++WD+             H++     +C +                   K   F      DE H      G  +    +Q  +L  K     +    +H+  VTC  YN    QV++   GSTV  W + TG+K+ +F   H ++ ++ +  D+   RLLTG  DG V++W+F NG+C          L   +  AV+  +I    K I+  GW+           RAI V+  Q     ++ +     W   +   H +DIL  A L    L T  Y G I++WN     + HV                  KL+S        P+AD             +   ++ +L FL++R        A+LV+ G  G V FW++ +  +L   F   +  G  + +       D  ++ L  GD  G++ +W+IE
Sbjct:    1 IAVAFTSKEVCFYDLLSKEEFACQYKLQGLKGTPICMDYWYDPLDANESILSFGDITGKVQAIAFTAA---LISLFERPASACEDGEATMTINWAELLSGCHKCCHILEHKLHQGDWVRQVTYNASLDAIISSTTSNTNSVVMAWREKS----------------------------KKRL--NMTSFNIAQGIHAFDYHSRLNLIATAGINNKVCLWNPYVVSKPVGVLWGHSASVIAVQFFVERKQLFSFSKDKVLRLWDIQ------------HQLSIQRIACSFP------------------KSQDFRCLFHFDEAH------GRLFISFNNQLALLAMKSEA--SKRVKSHEKAVTCVLYNSILKQVISSDTGSTVSFWMIDTGQKIKQFTGCHGNAEISTMALDANETRLLTGSTDGTVKIWDF-NGYC-------HHTLNVGQDGAVDISQILILKKKILVTGWERYDYASWKTIGRAITVFRPQ---NFNQFFIQPEEWKGGIQ--HHDDILCAAFLPPQTLVTGSYDGEIVLWNNSTENAHHVLHPDYQRLLKSKLDTKPQKLLSAGRSQPSHPMADHSTTGVRNFEIDTEGKNAVMRLCFLKARKNTAVTGGANLVSCGGSGYVRFWDIYKKQLL-AEFLAHSGVGSIIMST------DKMNRYLTTGDLDGWLKIWNIE 600          

Query:  419 IEERIDLTVLEELKAAFENAEYDRSGKLDLSEFKALLKEKLQLPTFEDIQTETLFKKIDWASSGAINWDEFCTYMQLEYAEKEETYLKAREMAFCLPA--RIENTP--HRENVIRITSTSDGS-FIAGSTDGILSFWSNTLELKKCKSVVTIEQSQRVKSKWIIDFLIMNEFNKIIVATGDREIEFFELSSFEPYC---RIHSLENVPLCLDYYVDKDNLDDCLILWGDRKGCVNILHLHATGECLRTWKKQPRS-----EGIAGIGMENVLS--NPSIKFYRWKVHN-DWVLKLKYYDSLRQIISCSNDEATALVIGCVEGSTQLDQQMKLKSMHQTKSKDMTFGNMLQPKRRISTDQTVFNIYKGIQTFDFGKSKNVLVTGGLDRIIRLWNPYVNSKPTGMLRGHNKPLVYVHIAEQENRIFSICADKCVKVWDLHDHNCLLTVR---PKGHRIRGDMQSCHYSDFAKSLMIA-TDQVSMLNIK 1816
            +E ++ +    +++ AFE+ +  +   +   +F   + E +   T E+     LF K+D A  G INWD+  +++ LE  E++E     R  A  +P    +E  P  H++ + ++    + S ++  S +G+L+ W   L+L++   + +   + ++K  W+   + +   NKI VA   +E+ F++L S E +    ++  L+  P+C+DY+ D  + ++ ++ +GD  G V  +   A    L +  ++P S     E    I    +LS  +        K+H  DWV ++ Y  SL  IIS +     ++V+   E S                            K+R+  + T FNI +GI  FD+    N++ T G++  + LWNPYV SKP G+L GH+  ++ V    +  ++FS   DK +++WD+     +  +    PK    R      H+ +    L I+  +Q+++L +K
Sbjct:   38 LENQLSVGDFVKIQKAFESPQPRKIICMSREDFTQKMTEIVGWGTKEEYGE--LFDKVDVAQDGFINWDKLTSFILLELYEQDE-----RAKATVVPQWKDLEFLPVKHKDTIQKVIFLKNSSHYLTISKEGLLAIWGEHLKLQETFPITS--DATKLKHLWVTSLVSLENVNKIAVAFTSKEVCFYDLLSKEEFACQYKLQGLKGTPICMDYWYDPLDANESILSFGDITGKVQAIAFTAA---LISLFERPASACEDGEATMTINWAELLSGCHKCCHILEHKLHQGDWVRQVTYNASLDAIISSTTSNTNSVVMAWREKS----------------------------KKRL--NMTSFNIAQGIHAFDYHSRLNLIATAGINNKVCLWNPYVVSKPVGVLWGHSASVIAVQFFVERKQLFSFSKDKVLRLWDIQHQLSIQRIACSFPKSQDFRCLF---HFDEAHGRLFISFNNQLALLAMK 478          

Query: 1580 LRGHNKPLVYVHIAEQENRIFSICADKCVKVWDLHDHNCLLTVRPKGHRIRGDMQSCHYSDFAKSLMIATDQVSMLNIKINPFVAEKQLDERHQRASYLGGCYFEQISQNTVLVNKPPVLHTDVAVTHKDPVTCCKYNEAFNQVVTCCEGSTVKLWNLSTGEKVFEFNEAHEDSGVTCLTFDSXXXXXXXXXXDGMVRMWNFNNGHCLTELKKEESDLKYAEISAVEYVEISRN-KFIVSVGWDRAINVY 2326
            L GH K +     +     + +  ADK VK+W++    C  T+   GH++   +    +S  ++ ++ A+D  ++   KI   V  +                                  T     H + V CC +N   + VV+     +V++W++ TG  +     AH D  V+ ++F+  G  + +G  DG+VR+W+  NG C+  L  +E+         V +V+ S N K+I++   D  + ++
Sbjct:   83 LEGHTKSISSAKFSPCGKYLGTSSADKTVKIWNMDHMICERTLT--GHKL--GVNDIAWSSDSRCVVSASDDKTL---KIFEIVTSRM---------------------------------TKTLKGHNNYVFCCNFNPQSSLVVSGSFDESVRIWDVKTGMCIKTL-PAHSDP-VSAVSFNRDGSLIASGSYDGLVRIWDTANGQCIKTLVDDEN-------PPVAFVKFSPNGKYILASNLDSTLKLW 283          

Query: 1580 LRGHNKPLVYVHIAEQENRIFSICADKCVKVWDLHDHNCLLTVRPKGHRIRGDMQSCHYSDFAKSLMIATDQVSMLNIKINPFVAEKQLDERHQRASYLGGCYFEQISQNTVLVNKPPVLHTDVAVTHKDPVTCCKYNEAFNQVVTCCEGSTVKLWNLSTGEKVFEFNEAHEDSGVTCLTFDSXXXXXXXXXXDGMVRMWNFNNGHCLTELKKEESDLKYAEISAVEYVEISRN-KFIVSVGWDRAINVY 2326
            L GH K +     +     + +  ADK VK+W++    C  T+   GH++   +    +S  ++ ++ A+D  ++   KI   V  +                                  T     H + V CC +N   + VV+     +V++W++ TG  +     AH D  V+ ++F+  G  + +G  DG+VR+W+  NG C+  L  +E+         V +V+ S N K+I++   D  + ++
Sbjct:   83 LEGHTKSISSAKFSPCGKYLGTSSADKTVKIWNMDHMICERTLT--GHKL--GVNDIAWSSDSRCVVSASDDKTL---KIFEIVTSRM---------------------------------TKTLKGHNNYVFCCNFNPQSSLVVSGSFDESVRIWDVKTGMCIKTL-PAHSDP-VSAVSFNRDGSLIASGSYDGLVRIWDTANGQCIKTLVDDEN-------PPVAFVKFSPNGKYILASNLDSTLKLW 283          

Query: 1466 KGIQTFDFGKSKNVLVTGGLDRIIRLWNPYVNSKPTGM---LRGHNKPLVYVHIAEQENRIFSICADKCVKVWDLHDHNCLLTVRPKGH 1723
            K +   D  +S  ++ TGG+D++++LW    +    G+   L GH + +  V  A+  +++ S   D  +K+W++ + +CL T+   GH
Sbjct:  478 KDVNCVDISESDALIATGGMDKLVKLWQVDTHKMQLGIAGTLSGHRRGVGDVKFAKNSHKLASCSGDMTIKIWNISEKSCLQTI--SGH 564          

Query: 1442 DQTVFNIYKGIQTFDFGKSKNVLVTGGLDRIIRLWNPYVNSKPTGMLRGHNKPLVYVHIAEQENRIFSICADKCVKVWDLHDHNCLLT----VRPKGHRIRGDMQSCHYSDFAKSLMIATDQVSMLNIKINPFVAEKQLDERHQRASYLGGCYFEQISQNTVLVNKPPVLHTDVAVTHKDPVTCCKYNEAFNQVVTCCEGSTVKLWNLSTGEKVFEFNEAHE--------DSGVTCLTFDSXXXXXXXXXXDGMVRMWNFNNGHCLTELKKEESDLKYAEISAVEYVEISRNKFIVSVGWDRAINVYIDQCEPGMHKSYYPQSRWLDDMSNGHKEDILTLATLKGHLLATADYHGTIIVWNLMSGHVF 2509
            +++ F I  G+ TF   +S N++VTGG D  +R+W+ Y+ ++P+ +L GHN  +V V +  +EN+++S+   K +KVWDLH+H  L T    VR   H    D+ + +Y    + L++A  +  +++IK  P V     D                                    TH  PV+   YN  F  +V+C   S + +W+  TG +       H         D  +T   FD   + LLTG RDG +++WN+NN   +  +    S +   E++AV +V + R   I+++GWDR +  + D     + + Y    +W       H +DI       G  + TA Y G II W L +G  +
Sbjct:  317 ERSNFRIPLGVSTFFVAESHNIVVTGGPDTFVRIWDVYIPTEPSAILTGHNGGIVLVFVQPEENKVYSVDYQKIIKVWDLHEHTLLQTYGDLVRLIHHS-ETDL-TYYYHSHLRELVVAGRK--LISIKCCPRVRVDLTD----------------------------------GNTHAAPVSVVLYNRLFRNIVSCGLDSYIIVWDPWTGRRKIIMKSCHTKMIYGEIIDIEITAACFDPLEQFLLTGARDGSLKIWNYNNAVVVRNM----SIMPDQEVTAVIWV-VDR---ILAMGWDRQVTEFNDV----VGREYGDPKKW----PKFHTDDITCADVKLGEGVVTATYSGEIIFWKLETGQPY 630          

Query: 2573 SINKLLFLQSRAKNKSSASLVASGPYGLVHFWNVKEGGILYGRFKGGTESGQSLTAMIACKDQDIDDKLLFIGDRFGFISVWDIENY------------------------------ANNKVETDC-PELLRRWRAHVSSITSLDLVLQSQVLITSSDDCTVRVWTFEGEYVGTFGQTEMWDLTNP 3037
            S+  +LFLQ+R +     S+  S   G +  ++  + G     F    ++G  +  M  C D+   ++ L+ G  FG+I VW I N+                              A   V     P L+  ++ H+ +I S+  +   +++ T S D + R+WT  G Y+GT G    W    P
Sbjct:  699 SVQAVLFLQTRPQTLKHGSVFISLDTGFIQVYSHHQRGGYIVEFLAVHKTGDCVLTM--CTDRK--NRYLYTGTAFGYIKVWYIVNFCVPESEKTHVCMPKLRLEFIFLRKELFMTRAKRAVRNQAEPLLVSSYKGHLKAINSIAFINLPKIIFTGSHDYSCRLWTQGGRYLGTLGTVLPWSRLTP 880          

Query: 1580 LRGHNKPLVYVHIAEQENRIFSICADKCVKVWDLHDHNCLLTVRPKGHRIRGDMQSCHYSDFAKSLMIATDQVSMLNIKINPFVAEKQLDERHQRASYLGGCYFEQISQNTVLVNKPPVLHTDVAVTHKDPVTCCKYNEAFNQVVTCCEGSTVKLWNLSTGEKVFEFNEAHEDSGVTCLTFDSXXXXXXXXXXDGMVRMWNFNNGHCLTELKKEESDLKYAEISAVEYVEISRN-KFIVSVGWDRAINVYIDQCEPGMHKSYYPQSRWLDDMSNGHKED----ILTLATLKGHLLATADYHGTIIVWNLMSGHVFFKL 2518
            L GH K +  V  +     + S  ADK +K+W  +D     T+   GH++   +    +S  ++ L+  +D  ++   K+      K L      ++Y                                 V CC +N   N +V+     +V++W++ TG K  +   AH D  V+ + F+  G  +++   DG+ R+W+  +G CL  L  +++         V +V+ S N K+I++   D  + ++ D  +    K+Y            GHK +        +   G  + +      + +WNL S  V  KL
Sbjct:   68 LAGHTKAVSAVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTIS--GHKL--GISDVAWSSDSRLLVSGSDDKTL---KVWELSTGKSLKTLKGHSNY---------------------------------VFCCNFNPQSNLIVSGSFDESVRIWDVRTG-KCLKTLPAHSDP-VSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDN-------PPVSFVKFSPNGKYILAATLDNTLKLW-DYSKGKCLKTY-----------TGHKNEKYCIFANFSVTGGKWIVSGSEDNMVYIWNLQSKEVVQKL 324          

Query: 1580 LRGHNKPLVYVHIAEQENRIFSICADKCVKVWDLHDHNCLLTVRPKGHRIRGDMQSCHYSDFAKSLMIATDQVSMLNIKINPFVAEKQLDERHQRASYLGGCYFEQISQNTVLVNKPPVLHTDVAVTHKDPVTCCKYNEAFNQVVTCCEGSTVKLWNLSTGEKVFEFNEAHEDSGVTCLTFDSXXXXXXXXXXDGMVRMWNFNNGHCLTELKKEESDLKYAEISAVEYVEISRN-KFIVSVGWDRAINVYIDQCEPGMHKSYYPQSRWLDDMSNGHKED----ILTLATLKGHLLATADYHGTIIVWNLMSGHVFFKL 2518
            L GH K +  V  +     + S  ADK +K+W  +D     T+   GH++   +    +S  ++ L+  +D  ++   K+      K L      ++Y                                 V CC +N   N +V+     +V++W++ TG K  +   AH D  V+ + F+  G  +++   DG+ R+W+  +G CL  L  +++         V +V+ S N K+I++   D  + ++ D  +    K+Y            GHK +        +   G  + +      + +WNL S  V  KL
Sbjct:   68 LAGHTKAVSAVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTIS--GHKL--GISDVAWSSDSRLLVSGSDDKTL---KVWELSTGKSLKTLKGHSNY---------------------------------VFCCNFNPQSNLIVSGSFDESVRIWDVRTG-KCLKTLPAHSDP-VSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDN-------PPVSFVKFSPNGKYILAATLDNTLKLW-DYSKGKCLKTY-----------TGHKNEKYCIFANFSVTGGKWIVSGSEDNMVYIWNLQSKEVVQKL 324          

Query: 1481 FDFGK----SKNVLVTGGLDRIIRLWNPYVNS--KPTGMLRGHNKPLVYVHIAEQENRIFSICADKCVKVWDLH--DHNCLLTVRPKGHRIRGDMQSCHYSDFAKSLMIATD--QVSMLNIKINPFVAEKQLDERHQR-----ASYLGGCYFEQISQNTVL----VNKPPVLHTDVAVTHKDPVTCCKYNEAFNQVVTCCEGSTVKLWNLSTGEKVFEFNEAHEDSGVTCLTFDSXXXXXXXXXXDGMVRMWNFNNGHCLTELKKEESDLKYAEISAVEYVEISRNKFIVSVGWDRAINVYIDQCEP 2344
            FDF K     K+ LVTGGLD ++++W+   ++  K    L+GH   +V V ++     I S   D  + +WD    D   LL+  P       D+ +  +S   K ++   +  ++SM +++     AE+ LD ++ +     A    G Y    + + ++    V    V+ T     H  PV    ++     ++T  +   +KL++++  + V   +  H  S V C+ F   G+   +   D  V++W+ +   CL     E +D    ++  V Y     N  + S   D+++N+Y   C P
Sbjct:   42 FDFDKKEARPKDFLVTGGLDDLVKVWDLQEDNTLKLRHKLKGHALGVVSVAVSSDGQTIASSSLDSTMCLWDARSGDKKHLLSFGPV------DLWTVQFSPCNKYVISGLNDGKISMYSVETGK--AEQTLDAQNGKYTLSIAYSPDGKYIASGAIDGIITIFDVAAGKVVQT--LEGHAMPVRSLCFSPNSQLLLTASDDGHMKLYDVTHSDVVGTLS-GHA-SWVLCVAFSEDGKHFASSSSDNSVKIWDTSERKCLHTF-AEHTD----QVWGVRYSP--GNDKVASASEDKSLNIYY--CPP 327          

Query:  431 IDLTVLEELKAAFENAEYDRSG--KLDLSEFKALLKEKLQLPTFEDIQTETLFKKIDWASSGAINWDEFCTYMQLEYAEKEETYLKAREMAFCLPARIENTPHRENVIRITSTSDGSFIAGSTDGILSFWSNTLELKKCKSVVTIEQSQRVKSKWIIDFLIMNEFNKIIVATGDREIEFFELSSFEPYCRIHSLENVPLCLDYYVDKDNLDDCLILWGDRKGCVNILHLHATGECLRTWKKQPRSEGIAGIGMENVLSNPSIKFYRWKVHNDWVLKLKYYDSLRQIISCSNDEATALVIGCVEGSTQLDQQMK-LKSMHQTKSKDMTFGNMLQPKRRISTDQTVFNIYKGIQTFDFGKSKNVLVTGGLDRIIRLWNPYVNSKPTGMLRGHNKPLVYVHIAEQENRIFSICADKCVKVWDLHDHNCLLTVRPKGHRIRGDMQSCHYSDFAKSLMIATDQVSMLNIKINPFVAEKQLDERHQRASYLGGCYFEQISQNTVLVNKPPVLHTDVAVTHKDPVTCCKYNEAFNQVVTCCEGSTVKLWNLSTGEKVFEFNEAHEDSGVTCLTFDSXXXXXXXXXXDGMVRMWNFNNGHCLTELKKEESDLKYAEISAVEYVEISRNKFIVSVGWDRAINVYIDQCEPGMHKSYYPQSRWLDDMSNGHKEDILTLATLKGHLLATADYHGTIIVWNLMSGHVFFKLISPVAXXXXXXXXXXXXXSINKLLFLQSRA---KNKSSASLVASGPYGLVHFWNVKEGGILYGRFKGGTESGQSLTAMIACKDQDIDDKLLFIGDRFGFISVWDIENYANNKVETDCPELLRRWRAHVSSITSLDLVLQSQVLITSSDDCTVRVWTFEGEYVGTFGQTEMWDLTNPKTFQHPMVPYDVLVHPQSLPDHPVLGPRMTIEQRKEQSKAESTHKAKMTKQHALQSENSTFTHKNVIYIDDEEINQQIEQKIYKEGKGKRLRFERMKPRNALSEDGGPNEYRSLQVFELAKTP 3406
            + +  L+ +K AF+  E+ ++G   LD +EF+ +++    L T +D Q + LF KID+   G I W E CTY+ LE  +KEET  +++  AF LPA ++     E ++RI    +G+ +    DG++SFW+  L LK  K++   E+S   +  W  DF++M E+NK+I+ATG RE++F+E SS EP C++ +LE VPL LDY   +   D+C+I++GD +GCVNIL + +  E LR WK+ P+ + I  I +++ + +P + F RWKVH DWV K+KY++S+  I+S S  E TALVIG +  ST   +QM+    +   +S  +T        +R + +QT+F + KG+ TFD  K+ N+LVTGG+D+++R+W PYV   PTG+L+GH+ P+ YV +  +   I+S+  D   K+W + D  CL T  P   +I+G++ +C YS  AK L IA+D +++L++K  P     Q+                                    V+HK+PV CC Y+E F QVV+C EGS +K+W++ TG  +FEF  AH DS +TC+TFD++GRRL+TGGRDG++++WNFNNG C+  L +E    K  EI    Y+ +  N F++SVGW R I++Y+D  E        P   W DDM NGHKEDIL +A    HLLAT  + G IIVWN++SG +  +  +P +   + +    ++ S+  L+FL++RA   +  SSA LV+SG  G V+FW+V  GG     F+  +   Q +T +   +    DD +LF  D  GFI V++++ YA    E + PE +  WRAH+ SIT L +V + Q L+TSS DC+VR+W   G+Y+GTFGQ E W +  P +++HP VPY++L+ P S+P HPVL   +         K+E+ +K         Q +N T +    I ++D +I        ++   G+R R    K  N  S   G  +Y +L+  +L   P
Sbjct:    2 VSINDLKHIKQAFD--EFAKAGIDMLDYAEFQTVMRSCPSLKTVKDTQIQHLFMKIDYTGDGKIEWHEICTYIFLENKKKEETVHRSKMAAFVLPAIVKFLNCGEPLLRIHFPPNGTVVTLREDGLVSFWTPKLHLKSKKNLFP-ERSITRRPNWATDFVLMPEYNKLIIATGSRELQFYEFSSLEPCCQLSALETVPLNLDYCSTRP--DECVIVYGDTEGCVNILLMKSIREKLRLWKRSPQVDNIPNISIDHAVESPEVTFIRWKVHQDWVSKVKYFESISSIVSSSAHEETALVIGSIHPSTYKQEQMRGTAEVSDERSTKVT--------QRATCNQTIFIVPKGVTTFDLCKNLNLLVTGGMDKVVRMWIPYVPRNPTGILKGHSAPVAYVCVTSENGHIYSVSTDNTAKIWHIKDQTCLFTAHPNSSQIKGELSACIYSSAAKGLYIASDSIALLSLKTKPQPKGIQI------------------------------------VSHKEPVLCCGYSEQFRQVVSCSEGSVIKIWDVETGALIFEFGCAHGDSAITCMTFDTSGRRLMTGGRDGLIKLWNFNNGQCVKILSREG---KCPEICDCSYLTLHGNTFVISVGWSRRIDIYLDSKEETQFIQ-RPTPSWQDDMRNGHKEDILCIAHCTPHLLATGSFDGEIIVWNVVSGRIQCRFQTPQS--QKISSSHVQNTSVLSLIFLKTRAFVPELASSAWLVSSGSRGYVNFWSVLNGGKFVASFQ-ASHLQQQITKLALTQ----DDSMLFTADHVGFIYVYNVKQYAMGP-EQNPPEKINFWRAHIRSITGLKIVDKDQFLLTSSMDCSVRLWNIHGDYIGTFGQEEDWRIETPSSWKHPAVPYEILIDPLSMPSHPVLDEEINQSDVLSSEKSENVNK---------QLDNQTDSDPPTI-LNDRDIEDGSISSWFRSEPGRRQRHAIFKHLNRASNRTGLKDYNTLKDLDLIVMP 928          

Query:  476 AEYDRSGKLDLSEFKALLKEKLQLPTFEDIQ---TETLFKKIDWASSGAINWDEFCTYMQLEYAEKEETYLKAREMAFCLPARIENTPHRE----NVIRITSTSDGSFIAGSTDGILSFWSNTLE----LKKCKSVVTIEQSQRVKSKWIIDFLIMNEFNKIIVATGDREIEFFELSSFEPYCRIH--SLENVPLCLDYYVDKDNL-DDCLILWGDRKGCVNILHLHATGECLRTWKKQPRSEGIAGIGMENVLSNPSIKFYRW--KVHNDWVLKLKYYDSLRQIISCSNDEATALVIGCVEGSTQLDQQMKLKSMHQTKSKDMTFGNMLQPKRRISTDQTVFNIYKGIQTFDFGKSKNVLVTGGLDRIIRLWNPYVNSKPTGMLRGHNKPLVYVHIAEQENRIFSICADKCVKVWDLHDHNCLLTVRPKGHRIRGDMQSCHYSDFAKSLMIATDQVSMLNIKINPFVAEKQLDERHQRASYLGGCYFEQISQNTVLVNKPPVLHTDVAVTHKDPVTCCKYNEAFNQVVTCCEGSTVKLWNLSTGEKVFEFNEAHEDSGVTCLTFDSXXXXXXXXXXDGMVRMWNFNNGHCLTELKKEESDLKYAEISAVEYVEISRNKFIVSVGWDRAINVYIDQCEPGMHKSYYPQSRWLDDMSNGHKEDILTL--ATLKGHLLATADYHGTIIVWNLMSGHVFFKLISPVAXXXXXXXXXXXXXSINKLLFLQSRAKNK--SSASLVASGPYGLVHFWNVKEGGILYGRFKGGTESGQSLTAMIACKDQDIDDKLLFIGDRFGFISVWDIENYANNKVETDC----PELLRRWRAHVSSITSLDLVL-QSQVLITS-SDDCTVRVWTFEGEYVGTFGQTEMWDLTNPKTFQ 3049
            +E   +  +   ++   LKE     T +D Q    E  F ++  +  G + W  F T+M   Y    ++    + +    P   + T +++     V+ +T +    +++ S  G L  W+  L     L+           ++    W+ D + M   +KI VAT +R I FF++++   + +IH   L +    L Y+ + +   + C+++WGD KG VN+L      + L       +S G   I ++++  + ++  Y+   K+H+  + ++ Y      II+ S+  A+A+VI        +D   K                          ++ V+ I KG++ FDF  S  +LVT G+   +RLWN YV S+PT +LR H   +V V I +   +IFS   D  +K+WD+    C+ T+      I+  + S     F   L +++D V ++  +   +VA  QLD+   R                               +  D  TC  YN    QV   C  ST+ +W++ TG +  E   AH +  V+C+  D   RRL+T   +G +++WN  N             +   E++    +    +  +++ GW R I  Y            Y ++         H EDIL +    + G LLAT  Y G II+W L     F ++                 L +++LLFLQSRA+      A+++ S   G V  W+V      +G+F    +SG+++T        D ++ LL  GD  G I VWDI  YA N  + +     P LL  W  H  +I S +++L +S+  I S S D    +WT EG  VG FG+ + WDL+NP T+Q
Sbjct:   62 SERVSANSMSFEDYFCCLKEA----TGQDYQRSDVEDFFNEMSISCDGRVEWQTFQTFMLQHYKHITQSMQPCQNLPISHPLIRKCTYNKQEAIVRVLALTRSPPMRYVSVSKRGTLIAWNRHLNHLKPLEMWGEAFNKRHHRKRFQGWVTDAVYMANVHKIAVATLNRGIHFFDVTTASGFEQIHLYGLTHFASALCYWYETEAPGEKCVLMWGDEKGSVNLLWFLQPFKGLFAMPFTIQS-GPVKISLQDIYMHSALASYQHIPKIHSMLINRILYEPRDDIIITSSDSSASAVVI--------IDVNQK-------------------------REKYVWRIEKGVKCFDFSCSLGLLVTAGVGPAVRLWNRYVTSRPTAVLRSHQTTVVDVVIHQALGKIFSYSKDAVLKIWDIPSQQCVKTLHLNFPNIQAGV-SPEQGSFPLLLNLSSDPVLLVTCR--EYVALLQLDKTETR-------------------------------SRSDLYTCALYNPHLQQVA--CADSTLTVWDVKTGIRRMEIRNAHGNEEVSCMALDVHQRRLITAATNGTIKVWNLLN----GLNLHNLEPVSNKEVTG---IICHHDDQLLATGWSRLITQY----SIAFSSDIYIKANLSWKSGCQHSEDILAMDHCPVLG-LLATGSYDGEIIIWALALQKPFTRV-------------QTVHLPVHRLLFLQSRAQQSHLRKAAVLLSSQAGFVCCWSVCGPRHNHGQFYVPDKSGENVTGF----STDPENNLLVTGDTTGCIKVWDIAQYALNNGDMESAAGFPPLLHSWSGHERAIVSSEVLLYESRFFILSVSMDRRACLWTHEGSCVGCFGEEQQWDLSNPDTYQ 842          

Query: 1580 LRGHNKPLVYVHIAEQENRIFSICADKCVKVWDLHDHNCLLTVRPKGHRIRGDMQSCHYSDFAKSLMIATDQVSMLNIKINPFVAEKQLDERHQRASYLGGCYFEQISQNTVLVNKPPVLHTDVAVTHKDPVTCCKYNEAFNQVVTCCEGSTVKLWNLSTGEKVFEFNEAHEDSGVTCLTFDSXXXXXXXXXXDGMVRMWNFNNGHCLTELKKEESDLKYAEISAVEYVEISRN-KFIVSVGWDRAINVYIDQCEPGMHKSYYPQSRWLDDMSNGHKED----ILTLATLKGHLLATADYHGTIIVWNLMSGHVFFKL 2518
            L GH K +  V  +     + S  ADK +K+W  +D     T+   GH++   +    +S  +  L+ A+D  ++   KI    + K L      ++Y                                 V CC +N   N +V+     +V++W++ TG K  +   AH D  V+ + F+  G  +++   DG+ R+W+  +G CL  L  +++         V +V+ S N K+I++   D  + ++ D  +    K+Y            GHK +        +   G  + +      + +WNL +  +  KL
Sbjct:   41 LAGHTKAVSSVKFSPSGEWLASSSADKLIKIWGAYDGKFEKTIS--GHKL--GISDVAWSSDSNLLVSASDDKTL---KIWDVSSGKCLKTLKGHSNY---------------------------------VFCCNFNPQSNLIVSGSFDESVRIWDVKTG-KCLKTLPAHSDP-VSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDN-------PPVSFVKFSPNGKYILAATLDNTLKLW-DYSKGKCLKTY-----------TGHKNEKYCIFANFSVTGGKWIVSGSEDNMVYIWNLQTKEIVQKL 297          

Query: 1469 GIQTFDFGKSKNVLVTGGLDRIIRLW------NPYVNSKPTGMLRGHNKPLVYVHIAEQENRIFSICADKCVKVWDLHDHNCLLTVRPKGHRIRGDMQSCHYSDFAKSLMIATDQVSMLNIKINPFVAEKQLDERHQRASYLGGCYFEQISQNTVLVNKPPVLHTDVAVTHKDPVTCCKYNEAFNQVVTCCEGSTVKLWNLSTGEKVFEFNEAHEDSGVTCLTFDSXXXXXXXXXXDGMVRMWNFNNGHCLTELK 2215
            G+       + N L T G D IIR+W      +PY+ S     +  H   +  + +      + S  +D  VKVW+ H   C+ T+R              + D+ K+L  A D+           VA   LD +          +   ++  T L      + T     +KD +     N+    +V+      +++W+  T  K+ +  + H D+ V  L  +  G + L+G  DG +R+W+     C+   +
Sbjct:   32 GVNALQLDPALNRLFTAGRDSIIRIWSVNQHKDPYIAS-----MEHHTDWVNDIVLCCNGKTLISASSDTTVKVWNAHKGFCMSTLRT-------------HKDYVKALAYAKDK---------ELVASAGLDRQ---------IFLWDVNTLTALTASNNTVTTSSLSGNKDSIYSLAMNQMGTVIVSGSTEKVLRVWDPRTCAKLMKL-KGHTDN-VKSLLLNRDGTQCLSGSSDGTIRLWSLGQQRCIATYR 248          

Query: 1469 GIQTFDFGKSKNVLVTGGLDRIIRLW------NPYVNSKPTGMLRGHNKPLVYVHIAEQENRIFSICADKCVKVWDLHDHNCLLTVRPKGHRIRGDMQSCHYSDFAKSLMIATDQVSMLNIKINPFVAEKQLDERHQRASYLGGCYFEQISQNTVLVNKPPVLHTDVAVTHKDPVTCCKYNEAFNQVVTCCEGSTVKLWNLSTGEKVFEFNEAHEDSGVTCLTFDSXXXXXXXXXXDGMVRMWNFNNGHCLTELK 2215
            G+       + N L T G D IIR+W      +PY+ S     +  H   +  + +      + S  +D  VKVW+ H   C+ T+R              + D+ K+L  A D+           VA   LD +          +   ++  T L      + T     +KD +     N+    +V+      +++W+  T  K+ +  + H D+ V  L  +  G + L+G  DG +R+W+     C+   +
Sbjct:   30 GVNALQLDPALNRLFTAGRDSIIRIWSVNQHKDPYIAS-----MEHHTDWVNDIVLCCNGKTLISASSDTTVKVWNAHKGFCMSTLRT-------------HKDYVKALAYAKDK---------ELVASAGLDRQ---------IFLWDVNTLTALTASNNTVTTSSLSGNKDSIYSLAMNQMGTVIVSGSTEKVLRVWDPRTCAKLMKL-KGHTDN-VKSLLLNRDGTQCLSGSSDGTIRLWSLGQQRCIATYR 246          

Query:  680 KAREMAFCLPARIENTPHRENVIRITSTSDGSFIAGSTDGILSFWSNTLELKKCKSVVTIEQSQRVKSKWIIDFLIMNEFNKIIVATGDREIEFFELSSFEPYCRIHSLENVPLCLDYYVDKDNLDDCLILWGDRKGCVNILHLHATGECLRTWKKQPRSEGIAGIGMENVLSNPSIKFYRWKVHNDWVLKLKYYDSLRQIISCSNDEATALVIGCVEGSTQLDQQMK-LKSMHQTKSKDMTFGNMLQPKRRISTDQTVFNIYKGIQTFDFGKSKNVLVTGGLDRIIRLWNPYVNSKPTGMLRGHNKPLVYVHIAEQENRIFSICADKCVKVWDLHDHNCLLTVRPKGHRIRGDMQSCHYSDFAKSLMIATDQVSMLNIKINPFVAEKQLDERHQRASYLGGCYFEQISQNTVLVNKPPVLHTDV-AVTHKDPVTCCKYNEAFNQVVTCCEGSTVKLWNLSTGEKVFEFNEAHEDSGVTCLTFDSXXXXXXXXXXDGMVRMWNFNNG--HCLTELKKEESDLKYAEISAVEYVEISRNKFIVSVGWDRAINVYIDQCEPGMHKSYYPQSRWLDDMSNGHKEDILTLATLKGHLLATADYHGTIIVWNLMSGHVFFKLISPVAXXXXXXXXXXXXXSINKLLFLQSRAKNKSSASLVASGPYGLVHFWNVKEGGILYGRFKGGTESGQSLTAMIACKDQDI--DDKLLFIGDRFGFISVWDIENYANNKVETDCPELLRRWRAHVSSITSLDLVLQSQVLITSSDDCTVRVWTFEGEYVGTFGQTEMWDLTNPKTFQHPMVPYDVLVHPQSLPDHPVLGPRMTIEQRKEQSKAESTHKAKMTKQHALQSENSTFTHKNV---IYIDDEEINQQIEQ-KIYKEGKGKRLRFERMKPRNALSEDGGPNEYRSLQVFEL-AKTPSPRQP 3421
            + ++++F LPA +  TPHRE +I+I+   D S +    DG++S W++ L+LKK + ++   + Q  K KWI D  +M ++NK+IV T DRE+ F+ELS+FEPYC+I  LE +PL L Y     + D+ ++ +GD +GC+N++ + +  E +R+W K    + I  + M+ + S   +K  RWKVHNDWV +++Y +++  IIS SND+ TALVIGCVEG+  + +++K L     T+SK       + PKR IS D+++F + +G++ FDF K  N+LVTGGLDRI+R+WNPYV   PTG LRGH+ P+ ++ IA++ ++I+S+  D  V VWD+ +H CL+ V  K  +I+G++ +C +S   ++L IATD  SML ++ +                                     + H DV +V+HK+PVTCC+YN+   QVV+C EGS +K+W+L TG+ V E   AH  + +TCL  D+TG R+ +  +DG ++ W+ ++    CLT LK+  +D          Y  +   +F++S G  + I ++ DQ +  + ++ YP   W+ +M N HK +IL +A+   +L+A++   G I +W++ SG++   L  P    +   +    DL I KL+FL SR      A L ASGP G + FW++ +GG ++G F        S     A +D  I  DD  L   D+  ++ +W+I  YA +  E   P L+  WRAH   IT +  V + ++++TSS DCTVR+W+ +GE +GTFGQ+E+W+    +++          +  QS         R   ++    S   + H +   +Q+     N +++ + +   + +DD++I +++ + + +   +GK    ++++        G  N Y+SLQ+ +L + T + R+P
Sbjct:   16 RNKKVSFHLPATVAETPHREPLIQISPMPDNSLLVVGQDGLISVWTSDLKLKKNRFILDENKQQNRKMKWIADLTLMPQYNKLIVGTCDRELRFYELSNFEPYCQIIGLETLPLHLGY--STRDTDEGVLYFGDEQGCINVILISSVAETIRSWTKCQIIDDIPSVSMDIIESAGHVKLIRWKVHNDWVTQIRYVNAIDSIISSSNDDYTALVIGCVEGTKNMQKRLKDLMDSSSTRSKRSMLSGNVPPKRNIS-DESLFKVKRGVKAFDFCKENNILVTGGLDRIVRIWNPYVPGWPTGSLRGHSSPITFLQIADENSKIYSVSTDCTVMVWDIEEHTCLINVISKASQIKGEIATCFFSSQFRALYIATDSFSMLQLQHS-------------------------------------ITHPDVPSVSHKEPVTCCQYNQYLEQVVSCSEGSVIKIWDLLTGKLVSEVRGAHGSAAITCLALDNTGSRMFSVAKDGSLKQWDLSSTSVSCLTTLKEAVADSLTDGQYDCTYAWLHNKRFMISAGCGKQITIFPDQQDSAVVENQYPNHTWISNMRNKHKGEILCVASCPPNLVASSSSDGEIFIWDVTSGNMMCSLGIP-KQEELSNETGSSDLIIQKLIFLSSRDWKNECAVLAASGPNGQITFWHIFDGGKVFGSFP-------SSHYQTAVRDMAISEDDSTLCAADQLFYVYIWNISQYALHGPEAHPPPLIHCWRAHQCDITRVVPVSKYKLVVTSSVDCTVRLWSMKGEPIGTFGQSELWEAKKRESW----------IGQQS-------DGRANTDEHPSASGCGAQHSSSSEEQN-----NKSYSPEFIGISVPVDDKDIAEELHRSRSHSAQRGKMFGPKQVELHQTC---GKLNAYQSLQICDLMSVTTNVRRP 867          

Query:  107 KIKIRPSSASGNIQTHQSYTTGLYDKKCLFLKDKIKESLPDSNKLKKAGTHIGFLKESQRI-------IEPKDEIRKPRRRTIEIVDGMDITKFIGREM--SLSLRKHNLLDKIEERIDLTVLEELKAAFENAEYDRSGKLDLSEFKALLKEKLQLPTFEDIQTETLFKKIDWASSGAINWDEFCTYMQLEYAEKEETYLKAREMAFCLPARIENTPHRENVIRITSTSDGSFIAGSTDGILSFWSNTLELKKCKSVVTIEQSQRVKSKWIIDFLIMNEFNKIIVATGDREIEFFELSSFEPYCRIHSLENVPLCLDYYVDKDNLDDCLILWGDRKGCVNILHLHATGECLRTWKKQPRSEGIA-GIGMENVLSNPSIKFYRWKVHNDWVLKLKYYDSLRQIISCSNDEATALVIGCVEGSTQLDQQMKLKSMHQTKSK----DMTFGNMLQPKRRISTDQTVFNIYKGIQTFDFGKSKNVLVTGGLDRIIRLWNPYVNSKPTGMLRGHNKPLVYVHIAEQENRIFSICAD---KCVKVWDLHDHNCLLTVRPKGHRIRGDMQ-SCHYSDFAKSLMIATDQVSMLNIKINPFVAEKQLDERHQRASYLGGCYFEQISQNTVLV---------------------NKP-PVLHTDVAVTHKDPVTCCKYNEAFNQVVTCCEGSTVKLWNLSTGEKVFEFNEA-HEDSG 2104
            K K+R SSA G ++T    +     ++   ++ + K +L  S  +       GF++E   +       +E +   RK RR ++ +V+ +   + +  +   + +LRK    +K+E ++ L  L++LK AF+  E +    LD+ +FK +LK+   L    D Q E LF KID+ +SG I WDEFCTYMQL+Y+E EE+  ++R ++F LPA +    H + ++R+    D + I    DG + FWS  L+LK+ K++   E+S +   KW+ DF IM ++NK+I+ TGDRE++F+ELS+ EPYC+I  LE +PL LDY     + D+CLIL+GD +GCVNIL L + G+ LR WKK PR + I   IG++N + +P + F  WKVH DWV ++KYYDS++ IIS SNDEATALVIGC  G+T ++QQMK    H   +K      T G    P++R + DQT F++YKG++TF F K  +++VTGG+DRIIR+WN YV ++ TGMLRGH  P+  + I+ +EN+IFSI  D   K VKVWD      L       +   GD   +C   D +   +I   +   L I  +         +R  ++  +  C + +I++N  ++                      +P P    D+   H++ + C   N   N + +      + +WN+ +G      N   H D+G
Sbjct:    4 KKKVRHSSALGKLETSNVPSLFGEIRQINGVQQRAKTALGAS--ITHTAPPNGFIEECSNLHLDLPDWLEKELIRRKQRRHSLGLVENVTEKESLQNQSDPARNLRK----EKMERQVTLEQLKKLKDAFKELENNGHKSLDVEKFKWVLKKCTGLQGANDEQIEKLFMKIDFTASGKIRWDEFCTYMQLDYSELEESNSRSRRISFILPATVHEMIHGDPILRVFPMPDNTLIMLREDGHIYFWSTQLKLKRDKAI--FEKSVKKMPKWVTDFTIMLQYNKLILGTGDRELQFYELSNLEPYCQITGLETMPLKLDYCA--TDTDECLILYGDDQGCVNILLLSSVGQTLRMWKKMPRPDNIVPTIGIDNAILSPHVSFISWKVHGDWVTQMKYYDSIKAIISASNDEATALVIGCTTGTTNVEQQMKDIKDHMKDTKWKKGPATIG---PPQKRAAGDQTAFHVYKGVKTFAFCKKNSLVVTGGMDRIIRMWNVYVPARVTGMLRGHTAPIFSLDISSEENKIFSIATDNTIKVVKVWDFETGKQLFEF----NGAHGDAGITCSTFDHSGRRLITGGRDGRLKIWNHNTGQCLHTLKRGAKSDEVCDCTYAEINKNRYIMAVGWDRRINMYYDSENDLHHFQEPQPCWQDDLIRGHREDILCIAQNPP-NLLASSSYDGEIIVWNMISGHIHCRLNSPIHADAG 692          

Query: 1931 PVLHTDVAVTHKDPVTCCKYNEAFNQVVTCCEGST---VKLWNLSTGEKVFEFNEAHEDSGVTCLTFDSXXXXXXXXXXDGMVRMWNFNNGHCLTELKKEESDLKYAEISAVEYVEISRNKFIVSVGWDRAINVYIDQCEPGMHKSYYPQSRWLDDMSNGHKEDILTLATLKGHLLATADYHGTIIVWNLMSGHVFFKLISPVAXXXXXXXXXXXXXSINKLLFLQSRAKN-KSSASLVASGPYGLVHFWNVKEGGILYGRFKGGTESGQSLTAMIACKDQDIDDKLLFIGDRFGFISVWDIENYANNKVETDCPELLRRWRAHVSSITSLDLVLQSQVLITSSDDCTVRVWTFEGEYVGTFGQTEMWDLTNPKTFQHPMVPYDVLVHPQSLPDHPVLGPRMTIEQRKEQSKAESTHKAKMTKQHALQSENSTFTHKNVIYIDDEEINQQIEQKIYKEGKGKRLRFERMKPRNALSEDGGPNEYRSLQVFELAKTP 3406
            P   T +   H  P+     +   N++ +    +T   VK+W+  TG+++FEFN AH D+G+TC TFD +GRRL+TGGRDG +++WN N G CL  LK+     K  E+    Y EI++N++I++VGWDR IN+Y D  E  +H    PQ  W DD+  GH+EDIL +A    +LLA++ Y G IIVWN++SGH+  +L SP+     D      D S++K+LFL++R KN + +ASL+++GP G V+FW++ +GG +   FK      Q+ +  +     + DD L+F  D  G+I V+DI  YA  + E +  +L+  WRAHV +IT L+++ + +V+++SS D  VR+W   GE++GTFGQ ++W++  P +++HPMVP+++L+ P+S+P HPVL      E+  + S+  S  K +  +   +Q E S     +V  I +E+IN++I+ +   + +GKRLR ER    +   + GGPN + +L+ F+LA  P
Sbjct:  489 PARVTGMLRGHTAPIFSLDISSEENKIFSIATDNTIKVVKVWDFETGKQLFEFNGAHGDAGITCSTFDHSGRRLITGGRDGRLKIWNHNTGQCLHTLKR---GAKSDEVCDCTYAEINKNRYIMAVGWDRRINMYYD-SENDLHHFQEPQPCWQDDLIRGHREDILCIAQNPPNLLASSSYDGEIIVWNMISGHIHCRLNSPI---HADAGKQFTDRSVSKILFLRTRTKNQRPTASLLSNGPQGSVNFWSLLQGGKMIASFKPSRMGSQASSLAV-----NEDDTLMFAADHTGYIYVYDITEYAMQETEKEPAKLVTLWRAHVDTITHLEVIDEDKVILSSSMDGAVRLWGLSGEFIGTFGQMDLWEIFTPASWKHPMVPFEILIDPESMPTHPVL------EEPADISEIISPEKKEAQEASHVQKEISYNPKLSVPAITEEDINEEIKNQHLSQSQGKRLRQERHVITHKPLDHGGPNTFHTLRYFDLANNP 966          

Query:  230 SNKLKKAGTHIGFLKESQRIIEPKDEIRKPRRRTIEIVDGMDITKFIGREMSLSL-RKHNLLDKIEERIDLTVLEELKAAFENAEYD-------------------------RSGKLDLSEFKALLKEKLQLPTFEDIQTETLFKKIDWASSGAINWDEFCTYMQLEYAEKEE------TYLKAREMAFCLPARIENTPHRENVIRITSTSDGSFIAGSTDGILSFWSNTLELKKCKSVVT-IEQSQRVKSK---WIIDFLIMNEFNKIIVATGDREIEFFELSSFEPYCRIH--SLENVPLCLDYYVDKDNLDD-CLILWGDRKGCVNILHL--HATGECLRTWKKQPRSEGIAGIGMENVLSNPSIKFYRW--KVHNDWVLKLKYYDSLRQIISCSNDEATALVIGCVEGSTQLDQQMKLKSMHQTKSKDMTFGNMLQPKRRISTDQTVFNIYKGIQTFDFGKSKNVLVTGGLDRIIRLWNPYVNSKPTGMLRGHNKPLVYVHIAEQENRIFSICADKCVKVWDLHDHNCLLTVRPKGHRIR-GDMQSCHYSDFAKSLMIATDQVSMLNIKINPFVAEKQLDERHQRASYLGGCYFEQISQNTVLVNKPPVLHTDVAVTHKDPVTCCKYNEAFNQVVTCCEGSTVKLWNLSTGEKVFEFNEAHEDSGVTCLTFDSXXXXXXXXXXDGMVRMWNFNNGHCLTELKKEESDLKYAEISAVEYVEISRNKFIVSVGWDRAINVYIDQCEPGMHKSYYPQSR-WLDDMSNGHKEDILTLATLKG-HLLATADYHGTIIVWNLMSGHVFFKLISPVAXXXXXXXXXXXXXSINKLLFLQSRAKNKSSASLVASGPYGLVHFWNVKEGGILYGRFKGGTESGQSLTAMIACKDQDIDDKLLFIGDRFGFISVWDIENY---ANNKVETDCPELLRRWRAHVSSITSLD-LVLQSQVLITS-SDDCTVRVWTFEGEYVGTFGQTEMWDLTNPKTF 3046
            +N L++    +  L+E +  +         +++ ++   G  + KF   E  LS  R  NL  ++EE+  L  L  L+ AF     D                          +G + L EF+ +L +      F+D   E LF ++D +  G ++W EFCTY+ L+Y +++       T+L    +  C   + E T     ++ I+S      ++ S  G+L+ W   L  +K   V      SQ  K +   W+ D + +   NKI +AT  R+I FF++S+   +   H  +L +VP    Y+ +K + +   L+LWG   G VN+L L    TG   + + + P   G   I M+ +  +  +  Y+    VH + + KL Y    + II+ S    ++L+I        ++Q+ K+ +                           + I KG+Q FD+ ++ N+LVTGG D  +RLWN YV  +P  +L  H+  ++ V I +   +IFS   D  +KVWD+    CL T+  K   I+ G +Q      F   L++ T+   +L +  + ++   +L     RA    G +F                      TH+ PVTC  Y+   + +VT  E STV +W++ TG K      AH    VTC+  D   RRL+TG R+G +++WN  NGH L +L+  E     AEI+ +  V    N F+ +VGW+R I  Y     P  ++ Y P +  W       H+EDILT        LLATA + G II+WN  +  ++  L                   ++KL FLQ R+  + +A LV+S   G + +W V  GG  +G F    E+  S+  + +    D  +++L  GD  G + VWDI  Y   A  +  T  P LL  W AH S++ S++  +  S+  I S S D T ++WT +G+ VGTFGQ++ W L++P ++
Sbjct:   11 ANALQRQLLSVTLLQELEHFL---------KKQGLQKCSGQKV-KFCNEESILSFDRNENL--RLEEKFRLDDLRLLQEAFAKHNSDGKETNCKEESDDLRATRRRAKQEARPAGNMTLDEFRRVLCDLFGSECFDD-DMELLFNEVDTSCDGYVDWGEFCTYLLLQYRKRDYRMIGRVTFLGQPVIRLCTRNKQEPT---SRILAISSPPPMWLLSVSKTGVLTTWDLALHPQKSYEVAAEYPDSQAGKRRFKCWVTDAVHLPNANKIAIATTSRDIHFFDVSTMNLFEEFHLFALNHVPTTFSYWYNKQSPESRSLLLWGGDNGAVNVLWLLQPQTGVFEKPFSQHP---GPTKIYMQELKDHSKLLSYQVIPDVHPEAITKLIYCPEKQLIITSSGSAQSSLLI------MDINQKGKVYT---------------------------WKINKGVQCFDYCRALNLLVTGGFDHKVRLWNQYVTCRPIAVLPEHSMAILDVMIYQPLGQIFSFSKDSVLKVWDIPSQTCLHTLVLKFPCIQPGRIQEQGSFPF---LLVPTNPSRLL-VCYSDYIGILRL----ARAEPTEGTFF----------------------THRAPVTCLLYSSFCHLIVTGSEDSTVAVWDVETGAKSLLLGNAHGQEEVTCMALDKAQRRLITGARNGTIKIWNIQNGHNLHQLEPVED----AEITCI--VASQENVFL-TVGWNRKIVTYDI---PKTNEVYVPANHSW--KGGQLHQEDILTADFCPSLGLLATASFDGEIILWNAETQRLYLYL--------RQCPQARSPAPVDKLFFLQKRSAKREAAILVSSEA-GTLRWWRVTNGGQEWGSFYAQDEADCSVLGLAS----DKANRVLVSGDTLGLVQVWDISAYGLQAAAQTYTCRPPLLYSWGAHDSAVVSVEHFLYDSEPFIASGSSDKTAKLWTVDGKQVGTFGQSKCWKLSDPTSY 893          

Query:  449 EELKAAFENA--EYDRSGKLDLSEFKALLKEKLQLPTFEDIQTETLFKKIDWASSGAINWDEFCTYMQLEYAEKEE------TYLKAREMAFCLPARIENTPHRENVIRITSTSDGSFIAGSTDGILSFWSNTLELKKCKSVVT-IEQSQRVKSK---WIIDFLIMNEFNKIIVATGDREIEFFELSSFEPYCRIH--SLENVPLCLDYYVDKDNLDD-CLILWGDRKGCVNILHL--HATGECLRTWKKQPRSEGIAGIGMENVLSNPSIKFYRW--KVHNDWVLKLKYYDSLRQIISCSNDEATALVIGCVEGSTQLDQQMKLKSMHQTKSKDMTFGNMLQPKRRISTDQTVFNIYKGIQTFDFGKSKNVLVTGGLDRIIRLWNPYVNSKPTGMLRGHNKPLVYVHIAEQENRIFSICADKCVKVWDLHDHNCLLTVRPKGHRIR-GDMQSCHYSDFAKSLMIATDQVSMLNIKINPFVAEKQLDERHQRASYLGGCYFEQISQNTVLVNKPPVLHTDVAVTHKDPVTCCKYNEAFNQVVTCCEGSTVKLWNLSTGEKVFEFNEAHEDSGVTCLTFDSXXXXXXXXXXDGMVRMWNFNNGHCLTELKKEESDLKYAEISAVEYVEISRNKFIVSVGWDRAINVYIDQCEPGMHKSYYPQSR-WLDDMSNGHKEDILTLATLKG-HLLATADYHGTIIVWNLMSGHVFFKLISPVAXXXXXXXXXXXXXSINKLLFLQSRAKNKSSASLVASGPYGLVHFWNVKEGGILYGRFKGGTESGQSLTAMIACKDQDIDDKLLFIGDRFGFISVWDIENY---ANNKVETDCPELLRRWRAHVSSITSLD-LVLQSQVLITS-SDDCTVRVWTFEGEYVGTFGQTEMWDLTNPKTF 3046
            ++L+A    A  E   +G + L EF+ +L +      F+D   E LF ++D +  G ++W EFCTY+ L+Y +++       T+L    +  C   + E T     ++ I+S      ++ S  G+L+ W   L  +K   V      SQ  K +   W+ D + +   NKI +AT  R+I FF++S+   +   H  +L +VP    Y+ +K + +   L+LWG   G VN+L L    TG   + + + P   G   I M+ +  +  +  Y+    VH + + KL Y    + II+ S    ++L+I        ++Q+ K+ +                           + I KG+Q FD+ ++ N+LVTGG D  +RLWN YV  +P  +L  H+  ++ V I +   +IFS   D  +KVWD+    CL T+  K   I+ G +Q      F   L++ T+   +L +  + ++   +L     RA    G +F                      TH+ PVTC  Y+   + +VT  E STV +W++ TG K      AH    VTC+  D   RRL+TG R+G +++WN  NGH L +L+  E     AEI+ +  V    N F+ +VGW+R I  Y     P  ++ Y P +  W       H+EDILT        LLATA + G II+WN  +  ++  L                   ++KL FLQ R+  + +A LV+S   G + +W V  GG  +G F    E+  S+  + +    D  +++L  GD  G + VWDI  Y   A  +  T  P LL  W AH S++ S++  +  S+  I S S D T ++WT +G+ VGTFGQ++ W L++P ++
Sbjct:   63 DDLRATRRRAKQEARPAGNMTLDEFRRVLCDLFGSECFDD-DMELLFNEVDTSCDGYVDWGEFCTYLLLQYRKRDYRMIGRVTFLGQPVIRLCTRNKQEPT---SRILAISSPPPMWLLSVSKTGVLTTWDLALHPQKSYEVAAEYPDSQAGKRRFKCWVTDAVHLPNANKIAIATTSRDIHFFDVSTMNLFEEFHLFALNHVPTTFSYWYNKQSPESRSLLLWGGDNGAVNVLWLLQPQTGVFEKPFSQHP---GPTKIYMQELKDHSKLLSYQVIPDVHPEAITKLIYCPEKQLIITSSGSAQSSLLI------MDINQKGKVYT---------------------------WKINKGVQCFDYCRALNLLVTGGFDHKVRLWNQYVTCRPIAVLPEHSMAILDVMIYQPLGQIFSFSKDSVLKVWDIPSQTCLHTLVLKFPCIQPGRIQEQGSFPF---LLVPTNPSRLL-VCYSDYIGILRL----ARAEPTEGTFF----------------------THRAPVTCLLYSSFCHLIVTGSEDSTVAVWDVETGAKSLLLGNAHGQEEVTCMALDKAQRRLITGARNGTIKIWNIQNGHNLHQLEPVED----AEITCI--VASQENVFL-TVGWNRKIVTYDI---PKTNEVYVPANHSW--KGGQLHQEDILTADFCPSLGLLATASFDGEIILWNAETQRLYLYL--------RQCPQARSPAPVDKLFFLQKRSAKREAAILVSSEA-GTLRWWRVTNGGQEWGSFYAQDEADCSVLGLAS----DKANRVLVSGDTLGLVQVWDISAYGLQAAAQTYTCRPPLLYSWGAHDSAVVSVEHFLYDSEPFIASGSSDKTAKLWTVDGKQVGTFGQSKCWKLSDPTSY 860          

Query:  776 FIAGSTDGILSFWSNTLELKKCKSVVT-IEQSQRVKSK---WIIDFLIMNEFNKIIVATGDREIEFFELSSFEPYCRIH--SLENVPLCLDYYVDKDNLDD-CLILWGDRKGCVNILHL--HATGECLRTWKKQPRSEGIAGIGMENVLSNPSIKFYRW--KVHNDWVLKLKYYDSLRQIISCSNDEATALVIGCVEGSTQLDQQMKLKSMHQTKSKDMTFGNMLQPKRRISTDQTVFNIYKGIQTFDFGKSKNVLVTGGLDRIIRLWNPYVNSKPTGMLRGHNKPLVYVHIAEQENRIFSICADKCVKVWDLHDHNCLLTVRPKGHRIR-GDMQSCHYSDFAKSLMIATDQVSMLNIKINPFVAEKQLDERHQRASYLGGCYFEQISQNTVLVNKPPVLHTDVAVTHKDPVTCCKYNEAFNQVVTCCEGSTVKLWNLSTGEKVFEFNEAHEDSGVTCLTFDSXXXXXXXXXXDGMVRMWNFNNGHCLTELKKEESDLKYAEISAVEYVEISRNKFIVSVGWDRAINVYIDQCEPGMHKSYYPQSR-WLDDMSNGHKEDILTLATLKG-HLLATADYHGTIIVWNLMSGHVFFKLISPVAXXXXXXXXXXXXXSINKLLFLQSRAKNKSSASLVASGPYGLVHFWNVKEGGILYGRFKGGTESGQSLTAMIACKDQDIDDKLLFIGDRFGFISVWDIENY---ANNKVETDCPELLRRWRAHVSSITSLD-LVLQSQVLITS-SDDCTVRVWTFEGEYVGTFGQTEMWDLTNPKTF 3046
             ++ S  G+L+ W   L  +K   V      SQ  K +   W+ D + +   NKI +AT  R+I FF++S+   +   H  +L +VP    Y+ +K + +   L+LWG   G VN+L L    TG   + + + P   G   I M+ +  +  +  Y+    VH + + KL Y    + II+ S    ++L+I        ++Q+ K+ +                           + I KG+Q FD+ ++ N+LVTGG D  +RLWN YV  +P  +L  H+  ++ V I +   +IFS   D  +KVWD+    CL T+  K   I+ G +Q      F   L++ T+   +L +  + ++   +L     RA    G +F                      TH+ PVTC  Y+   + +VT  E STV +W++ TG K      AH    VTC+  D   RRL+TG R+G +++WN  NGH L +L+  E     AEI+ +  V    N F+ +VGW+R I  Y     P  ++ Y P +  W       H+EDILT        LLATA + G II+WN  +  ++  L                   ++KL FLQ R+  + +A LV+S   G + +W V  GG  +G F    E+  S+  + +    D  +++L  GD  G + VWDI  Y   A  +  T  P LL  W AH S++ S++  +  S+  I S S D T ++WT +G+ VGTFGQ++ W L++P ++
Sbjct:    3 LLSVSKTGVLTTWDLALHPQKSYEVAAEYPDSQAGKRRFKCWVTDAVHLPNANKIAIATTSRDIHFFDVSTMNLFEEFHLFALNHVPTTFSYWYNKQSPESRSLLLWGGDNGAVNVLWLLQPQTGVFEKPFSQHP---GPTKIYMQELKDHSKLLSYQVIPDVHPEAITKLIYCPEKQLIITSSGSAQSSLLI------MDINQKGKVYT---------------------------WKINKGVQCFDYCRALNLLVTGGFDHKVRLWNQYVTCRPIAVLPEHSMAILDVMIYQPLGQIFSFSKDSVLKVWDIPSQTCLHTLVLKFPCIQPGRIQEQGSFPF---LLVPTNPSRLL-VCYSDYIGILRL----ARAEPTEGTFF----------------------THRAPVTCLLYSSFCHLIVTGSEDSTVAVWDVETGAKSLLLGNAHGQEEVTCMALDKAQRRLITGARNGTIKIWNIQNGHNLHQLEPVED----AEITCI--VASQENVFL-TVGWNRKIVTYDI---PKTNEVYVPANHSW--KGGQLHQEDILTADFCPSLGLLATASFDGEIILWNAETQRLYLYL--------RQCPQARSPAPVDKLFFLQKRSAKREAAILVSSEA-GTLRWWRVTNGGQEWGSFYAQDEADCSVLGLAS----DKANRVLVSGDTLGLVQVWDISAYGLQAAAQTYTCRPPLLYSWGAHDSAVVSVEHFLYDSEPFIASGSSDKTAKLWTVDGKQVGTFGQSKCWKLSDPTSY 687          

Query: 1085 KGCVNILHLHATGECLRTWKKQPRSEGIAGIGMENVLSNPSIKFYRWKVHNDWVLKLKYYDSLRQIISCSNDEATALVIGCV----------EGSTQLDQQM-KLKSMHQTKSKDMTFGNMLQPKRRISTDQTVFNIYKGIQTFDFGKSKNVLVTGGLDRIIRLWNPYVNSKPTGMLRGHNKPLVYVHIAEQENRIFSICADKCVKVWDLHDHNCLLTVRPKGHRIRGDMQSCHYSDFAKSLMIATDQVSMLNIKINPFVAEKQLDERHQRASYLGGCYFEQISQNTVLVNKPPVLHTDVAVTHKDPVTCCKYNEAFNQVVTCCEGSTVKLWNLSTGEKVFEFNEAHEDSGVTCLTFDSXXXXXXXXXXDGMVRMWNFNNGHCLTELKKEESDLKYAEISAVEYVEISRNKFIVSVGWDRAINVYIDQCEPGMHKSYYPQSRWLDDMSNGHKEDILTLATLKGHLLATADYHGTIIVWNLMSGHVFFKLISPVAXXXXXXXXXXXXXSINKLLFLQSRAK--NKSSASLVASGPYGLVHFWNVKEGGILYGRFKGGTESGQSLTAMIACKDQDIDDKLLFIGDRFGFISVWDIENYANNKVETDCPELLRRWRAHVSSITSLDLVLQSQVLITSSDDCTVRVWTFEGEYVGTFGQTEMWDLTNPKTFQHPMVPYDVLVHPQSLPDHPVLG---PRMTIEQRKEQSKAESTHKAKMTKQHALQSENSTFTHKNVIYIDDEEINQQIEQKIYKEGKGK----RLRFERMKPRNALSEDGGPNEYRSLQVFELA 3397
            +GCVNIL L + GE LRTWKK PR E +  I + +V+++P+ ++ RWKVH D+V +L YY+S++ +IS SN E TALVIG +           G+T + +++ +++++ +      +   +  P+R+   ++TVF ++KG++ F F + KN+LVTGGLDRIIR+WNPY+  KPTG+LRGH  P++YVH+A +EN++FS+ AD  VKVWDL  H C  T+  K   I+G++ +C Y    ++L +AT  ++ L++K+   V E  L   HQ                                   +PV CC+YN AF  VV+CCE S VK+W+  TG +V EF   H ++G+TCLTFDS+GRRL+TGGRDG +++W++NNGHCL  L+ +E+    +E+    Y+E++RN+ +++VGWDR INVY D      H    PQ  W DD+++GHKEDIL +A     LLAT+ Y G IIVWN++SGH++ KL +P + +D        D S+++L FL++R    + +SA+L+++GP G V FW +  G  L   F    E  Q    ++        D L ++ D+ GFI V+DI+ Y     E   P  +  WRAHVS +TSL+L+    ++++SS DCTVR+W+ +G Y+GTFGQ   WD+  P ++ HP VP+++L  P+S+P H VL    P   +E R+EQ              H  + ++     K       E +  + E K  K         RL   R KPR  + E   P+ Y++L+  ELA
Sbjct:    5 QGCVNILFLASVGELLRTWKKMPRVEDMPSITLHSVMASPNAEYVRWKVHGDFVSQLNYYESMKAVISSSNHEPTALVIGSLLNRLEHGGFTVGATDIKEKLNEIRNVGKNVKMGNSSACLALPQRQAECNRTVFRVHKGVKAFSFCRRKNLLVTGGLDRIIRVWNPYLPGKPTGVLRGHRAPVMYVHVAFEENKVFSMSADNTVKVWDLETHGCCCTISSKASGIKGELTACLYLPGPRALCVATGTLAFLHLKVGS-VPESHLVRSHQ-----------------------------------EPVVCCRYNPAFRHVVSCCEASVVKVWDFETGRQVSEFIGTHGNAGITCLTFDSSGRRLVTGGRDGCLKIWSYNNGHCLHTLQHDENQ---SEVCDCTYMEVNRNRCVIAVGWDRRINVYFD-IPRDFHHFRKPQPHWQDDLNHGHKEDILCVAQCPPFLLATSSYDGEIIVWNVISGHMYCKLNTP-SPMDGQDHREGPDRSVSQLAFLKTRLTKLDSASAALISNGPGGSVCFWKLFSGSGLVANFTPSREKAQVSGIVVTS-----GDTLAYLADQHGFIHVYDIQEYGLQGTELQAPNTVTSWRAHVSMVTSLELIEGGSIVLSSSLDCTVRLWSQDGAYIGTFGQNHPWDVFTPDSWGHPRVPFEILTDPRSMPTHRVLETDVPAGCLEGRQEQ-------------DHGTEEKDPCEAEKTPNPPSPEGLTVEAEAKADKSRWAAFCHGRLLSARRKPRWKMPELRWPSIYQALRCHELA 736          

Query: 1493 KSKNVLVTGGLDRIIRLWNPYVNSKPTGMLRGHNKPLVYVHIAEQENRIFSICADKCVKVWDLHDHNCLLTVRPKGHRIRGDMQSCHYSDFAKSLMIATDQVSMLNIKINPFVAEKQLDERHQRASYLGGCYFEQISQNTVLVNKPPVLHTDVAVTHKDPVTCCKYNEAFNQVVTCCEGSTVKLWNLSTGEKVFEFNEAHEDSGVTCLTFDSXXXXXXXXXXDGMVRMWNFNNGHCLTELKKEESDLKYAEISAVEYVEISRNKFIVSVGWDRAINVYIDQCEPGMHKSYYPQSRWLDDMSNGHKEDILTLATLKGHLLATADYHGTIIVWNLMSGHVFFKLISPVAXXXXXXXXXXXXXSINKLLFLQSRAK--NKSSASLVASGPYGLVHFWNVKEGGILYGRFKGGTESGQSLTAMIACKDQDIDDKLLFIGDRFGFISVWDIENYANNKVETDCPELLRRWRAHVSSITSLDLVLQSQVLITSSDDCTVRVWTFEGEYVGTFGQTEMWDLTNPKTFQHPMVPYDVLVHPQSLPDHPVLG---PRMTIEQRKEQSKAESTHKAKMTKQHALQSENSTFTHKNVIYIDDEEINQQIEQKIYKEGKGK----RLRFERMKPRNALSEDGGPNEYRSLQVFELA 3397
            + KN+LVTGGLDRIIR+WNPY+  KPTG+LRGH  P++YVH+A +EN++FS+ AD  VKVWDL  H C  T+  K   I+G++ +C Y    ++L +AT  ++ L++K+   V E  L   HQ                                   +PV CC+YN AF  VV+CCE S VK+W+  TG +V EF   H ++G+TCLTFDS+GRRL+TGGRDG +++W++NNGHCL  L+ +E+    +E+    Y+E++RN+ +++VGWDR INVY D      H    PQ  W DD+++GHKEDIL +A     LLAT+ Y G IIVWN++SGH++ KL +P + +D        D S+++L FL++R    + +SA+L+++GP G V FW +  G  L   F    E  Q    ++        D L ++ D+ GFI V+DI+ Y     E   P  +  WRAHVS +TSL+L+    ++++SS DCTVR+W+ +G Y+GTFGQ   WD+  P ++ HP VP+++L  P+S+P H VL    P   +E R+EQ              H  + ++     K       E +  + E K  K         RL   R KPR  + E   P+ Y++L+  ELA
Sbjct:   10 RRKNLLVTGGLDRIIRVWNPYLPGKPTGVLRGHRAPVMYVHVAFEENKVFSMSADNTVKVWDLETHGCCCTISSKASGIKGELTACLYLPGPRALCVATGTLAFLHLKVGS-VPESHLVRSHQ-----------------------------------EPVVCCRYNPAFRHVVSCCEASVVKVWDFETGRQVSEFIGTHGNAGITCLTFDSSGRRLVTGGRDGCLKIWSYNNGHCLHTLQHDENQ---SEVCDCTYMEVNRNRCVIAVGWDRRINVYFD-IPRDFHHFRKPQPHWQDDLNHGHKEDILCVAQCPPFLLATSSYDGEIIVWNVISGHMYCKLNTP-SPMDGQDHREGPDRSVSQLAFLKTRLTKLDSASAALISNGPGGSVCFWKLFSGSGLVANFTPSREKAQVSGIVVTS-----GDTLAYLADQHGFIHVYDIQEYGLQGTELQAPNTVTSWRAHVSMVTSLELIEGGSIVLSSSLDCTVRLWSQDGAYIGTFGQNHPWDVFTPDSWGHPRVPFEILTDPRSMPTHRVLETDVPAGCLEGRQEQ-------------DHGTEEKDPCEAEKTPNPPSPEGLTVEAEAKADKSRWAAFCHGRLLSARRKPRWKMPELRWPSIYQALRCHELA 594          

Query:  188 CLFLKDKIKESLPDSNKLKKAGTHIGFLKESQRIIEPKDEIRKPRRRTIEIVDGMDITKFIGREMSLSLRKHNL-LDKIEERIDLTVLEELKAAFENAEYDRSGKLDLSEFKALLKEKLQLPTFEDIQTETLFKKIDWASSGAINWDEFCTYMQLEYAEKEETYLKAREMAFCLPARIENTPHRENVIRITSTSD-----GSFIAGSTDGILSFWSNTLELKKCKSVVTIEQSQRV--KSKWIIDFLIMNEFNKIIVATGDREIEFFELSSFEPYC----RIHSLENVPLCLDYYVDKDNLDDCLILWGDRKGCVNILHLHATGECLRTWKKQPRS---EGIAGIGMENVLSN--PSIKFYRWK-VHNDWVLKLKYYDSLRQIISCSNDEATALVIGCVEGSTQLDQQMKLKSMHQTKSKDMTFGNMLQP-KRRISTDQTVFNIYKGIQTFDFGKSKNVLVTGGLDRIIRLWNPYVNSKPTGMLRGHNKPLVYVHIAEQENRIF-SICADKCVKVWDLHDHNCLLTVRPKGHRIRGDMQSCHYSDFAKSLMIATDQVSMLNIKINPFVAEKQLDERHQRASYLGGCYFEQISQNTVLVNKPPVLHTDVAVTHKDPVTCCKYNEAFNQVVTCCEGSTVKLWNLSTGEKVFEFN-EAHEDSGVTCLTFDSXXXXXXXXXXDGMVRMWNFNNGHCLTELKKEESDLKYAEISAVEYVEISRNKFIVSVGWDRAINVYIDQCEPGMHKSYYPQSRWLDDMSNGHKEDILTLATLKGHLLATADYHGTIIVWNL 2491
            CL L    +   P     +K G       + Q++ +P    +K   R++ + D                  HN  +++ +++     L +L+  FE  E D +G L    F  ++K  L   +  +   E LF K+D   +G + W ++  YM  E+  KEE       + F LP  +    H   V+++   +      G F+  + DGIL FWS T  + +      + QS++   +  W+ID   ++  + I VA+ + +IEFF++  ++  C     +  L++  + +DY+ D      C   +GD KG   I         L   +  PR+   +    + ++ +L+   P  + +R K +H +W  ++KY   L  + SCS  E ++LV+  + G                           +P K R+S+     N+ KGI  FD+   +N L TGG D  IRLWNP V+ KP  +++GH   + ++ +  +   I  SI  DK ++VWDL D+ CL +   K   +     +  Y   + +L+ +T  + +L                          Y E  SQ          L T    TH  P+    Y++ F QVV+ C    V +W++STG+K  E      ++S +T +  D + R LLTG RDG ++MWN+N G CL      +      EIS + ++    NK   + GW + I  +  Q        Y+ QS         H EDIL++   +   L T+ Y+G I+ WN+
Sbjct:   45 CLLLFFPFRARWPRLMSSEKPGES----PKPQKMAQPGGSQKKETSRSVPVTDPTS---------------HNSEINQRDQQFSDMHLADLQKVFEK-EADENGALKKEGFIRIMKGVLS--SMSEEMLELLFLKVDSDCNGFVTWQKYVDYMMREFQGKEEMRKSQYRLRFHLPMTVIPLHHGSEVVKVACLTKRFKKMGRFLTVTKDGILQFWSETFSMLES---FHLSQSKQYGHQQMWVIDVAYLHNMSLIAVASTELKIEFFDIGGYK--CIRAFTVIDLDSCVMVMDYWTDCHKAVFC---YGDTKGNATIFISDNVAGGLFNPQILPRASKWDHWFTVSLKKLLNEKAPLYRSFRMKGLHPNWCQQVKYIPQLNVVASCSAVEKSSLVLIILPGK--------------------------EPEKPRLSS----LNLRKGILCFDYCPDRNFLATGGYDPHIRLWNPLVSKKPVWLMKGHQTSVTHLLVNSRNASILISISRDKNIRVWDLQDYVCLQSFCGKLFPLGNCPITSTYFYRSSTLICSTYNIGILR------------------------GYLE--SQGP--------LKTGRMTTHNTPLCAVLYSKIFKQVVSGCLQGLVSVWDISTGKKRMEIPVSGIQESELTAMALDQSERCLLTGLRDGTMQMWNYNTGECLMTFPNPDR----VEISGIVHM----NKVFYTTGWSKRITNFTFQKITQALSCYHWQSF--------HTEDILSMDKYQNQFLGTSSYNGDIVFWNV 723          

Query: 2573 SINKLLFLQSRAKNKSSASLVASGPYGLVHFWNVKEGGILYGRFKGGTESGQSLTAMIACKDQDIDDKLLFIGDRFGFISVWDIENY-----------ANNKVETDC-------------------------------------PELLRRWRAHVSSITSLDLVLQSQVLITSSDDCTVRVWTFEGEYVGTFG 3007
            S+ K+LFLQ+R +   +A+L++S   G ++ W++   G L G+F    E G+S+   +A    D +D +L  GD  G I +WDI++Y           + N +  D                                      P LL  W +H+ S+T +  V   Q+++++  D  V+ W   G+ +GTFG
Sbjct:  851 SVEKILFLQTRPRLPHTAALLSSSIDGFIYAWSIHGNGGLLGKFSVDNEVGESVVGAMAT---DENDWILLTGDSKGNIKIWDIKDYCYFIDQQPLQSSGNSLSVDTENKFRLLIPKQLQVCSEHHLPQEEKEVVEGQTFSLVPPPLLITWNSHLDSVTDILYVNSFQLVVSAGQDRDVKAWRLSGDAIGTFG 1040          

Query: 1448 TVFNIYKGIQTFDFGKSKNVLVTGGLDRIIRLWNPYVNSKPTGMLRGHNKPLVYVHIAEQENRIFSICADKCVKVWDLHDHNCLLTVRPKGHRIRGDMQSCHYSDFAKSLMIATDQVSMLNIKINPFVAEKQLDERHQRASYLGGCYFEQISQNTVLVNKPPVLHTDVAVTHKDPVTCCKYNEAFNQVVTCCEGSTVKLWNLSTGEKVFEFNEAHEDSGVTCLTFDSXXXXXXXXXXDGMVRMWNFNNGHCLTELKKEESDLKYAEISAVEYVEISRNKFIVSVGWDRAINVYIDQCEPGMHKSYYPQS-RWLDDMSNGHKEDILTLATLKGHLLATADYHGTIIVWN---------LMSGHVFFKLISPVAXXXXXXXXXXXXXS-----------------------INKLLFLQSRAKNKSS--ASLVASGPYGLVHFWNVKEGGILYGRFKGGTESGQSLTAMIACKDQDIDDKLLFIGDRFGFISVWDIENYANNKVE---TDCPELLRRWRAHVSSITSLDLVLQSQ--VLITSSDDCTVRVWTFEGEYVGTFGQTEMWDLTNPKTFQHPMVPYDVLVHPQSLPDHPVLGPRMTIEQRKEQSKAESTHKAKMTKQHALQSENSTFTHKNVIYIDDEEINQQIEQKIYKEGKGKRLRFERMKPRNALSEDGGPNEYRSLQVFELAKTPSPRQPEIL 3430
            T FNI +GI  FD+    N++ T G++  + LWNPYV SKP G+L GH+  ++ V    +  ++FS   DK +++WD+             H++     +C +                   K   F    Q DE H      G  +    +Q  +L  K     +    +H   V+C  YN    QV++   GSTV  W + TG+K+ +F   H ++ ++ +  D+   RLLTG  DG V++W+F NG+C   L   +  +   +IS +  ++    K I+ VGW+RA+ V+     P     ++ QS  W   +   H++DIL  A      L T  Y G I++WN         L  G+   +L S V    +  +      S                       + +L FL++R    ++  A+LV+ G  G V FW+  +  +L   F      G  + +       D  ++ L  GD  G++ +W+IE Y  N  E   T  P LLR  + H   I+SL++       ++I+SS DC+V V          FGQ   W++ N   F  P    + L+  ++  +   + P  +    KE+   +ST  + +T++     +NST       ++  EE+N  ++ K     +   L+ +  KP          + + SL +  L + P  ++P  L
Sbjct:   22 TSFNIAQGIHAFDYHSRLNLIATAGINNKVCLWNPYVLSKPVGVLWGHSASVIAVQFFAERKQLFSFSRDKVLRLWDIQ------------HQLSIQRITCSFP------------------KSQDFRCLFQFDETH------GRLFISFNNQLALLAIKNEA--SKRVKSHLKAVSCVLYNSLLKQVISSDVGSTVSFWMIETGQKIKQFAGCHGNAEISTMALDANKTRLLTGSTDGTVKVWDF-NGYCHYTLNVGQDGV--VDISQILVLK----KTILVVGWERALIVF----RPQNFNQFFIQSEEWKGGVH--HQDDILCAAFSPPQTLVTGSYDGEIVLWNNNTENAHHALHPGYQ-RQLTSMVDVEAQKLNSRRSCESHGVADQATQAARNVKIDTEGNNAVMRLCFLEARKTKAATGGANLVSCGASGYVRFWDTFK-KVLLAEFLAHAGVGSIIMST------DKLNQYLATGDSDGWLKIWNIEEYCTNSTESKITQPPPLLRSSQPHEDRISSLEMCESCGRLLIISSSADCSVCVTGLSSAPALIFGQASHWNIEN--HFSLPERDTN-LIESKNQEERMKVNPLFS----KEELCLDSTEHSLLTEE---DEDNST-------HLSTEEMNFSLKYK-----RRNSLKKKAYKPCYGEIIQTSTSTFGSLCLRTLKELPEVKKPAFL 641          

Query:  413 DKIEERIDLTVLEELKAAFENAEYDRSGKLDLSEFKALLKEKLQLPTFEDIQTETLFKKIDWASSGAINWDEFCTYMQLEYAEKEETYLKAREMAFCLPA--RIENTP--HRENVIRITSTSDGS-FIAGSTDGILSFWSNTLELKKCKSVVTIEQSQRVKSKWIIDFLIMNEFNKIIVATGDREIEFFELSSFEPY-C--RIHSLENVPLCLDYYVDKDNLDDCLILWGDRKGCVNILHLHATGECL--RTWKKQPRSEGIAGIGMENVLS--NPSIKFYRWKVHN-DWVLKLKYYDSLRQIISCSNDEATALVIGCVEGSTQLDQQMKLKSMHQTKSKDMTFGNMLQPKRRISTDQTVFNIYKGIQTFDFGKSKNVLVTGGLDRIIRLWNPYVNSKPTGMLRGHNKPLVYVHIAEQENRIFSICADKCVKVWDLHDHNCLLTVR---PKGHRIRGDMQSCHYSDFAKSLMIA-TDQVSMLNIK 1816
            D  E ++ +    +++  FE+ +  ++  +   EF   + E +   T E+     LF K+D A  G I+WD+  +++ L   E++E     R  A  +P    +E  P  H++ + ++      S ++  S +G+L  W   L+L++  S+     + ++K  W+   + +   NKI VA   REI F++L S E + C  ++  L+  P+C+DY+ D  +  D ++ +GD  G V  +   A    L  R        E    I    ++S  +      +  +H+ DWV ++ Y  SL   IS +      +V+   E S +L   +K+ S                           FNI +GI  FD+    N++ T G++  + LWNPYV SKP G+L GH+  ++ V    +  ++FS   DK +++WD+     +  +    PK    R   Q   + +    L I+  +Q+++L IK
Sbjct:   44 DLFENKLSVEDFVKIQQVFESQDPSQTICMPREEFVQKMAETVGWGTKEEYGE--LFDKVDVARDGFIDWDKLTSFILLLLYERDE-----RAKATVVPQWKDLEFLPGKHKDTIQKVVFLKSSSRYLTVSKEGLLGIWGENLKLQE--SLPITSDAIKLKHLWVTSLVSLENVNKIAVAFTSREICFYDLLSKEEFPCQYKLQGLQGAPICMDYWYDPIDPKDSILSFGDITGKVQAVAFTAAMISLFERPANACDNEEATMTIDWAELVSGCHKCCHVLQHTLHHGDWVRQVTYNASLDAFISSTMSGINTVVLAWREKSKKL---LKMTS---------------------------FNIAQGIHAFDYHSRLNLIATAGINNKVCLWNPYVLSKPVGVLWGHSASVIAVQFFAERKQLFSFSRDKVLRLWDIQHQLSIQRITCSFPKSQDFRCLFQ---FDETHGRLFISFNNQLALLAIK 486          

Query: 1418 QPKRRISTDQTVFNIYKGIQTFDFGKSKNVLVTGGLDRIIRLWNPYVNSKPTGMLRGHNKPLVYVHIAEQENRIFSICADKCVKVWDLHDHNCLLTVRPKGHRIRGDMQSCHYSDFAKSLMIATDQVSMLNIKINPFVAEKQLDERHQRASYLGGCYFEQISQNTVLVNKPPVLHTDVAVTHKDPVTCCKYNEAFNQVVTCCEGSTVKLWNLSTGEKVFEFNEAHEDSGVTCLTFDSXXXXXXXXXXDGMVRMWNFNNGHCLTELKKEESDLKYAEISAVEYVEI-SRNKFIVSVGWDRAINVYIDQCEPGMHKSYYPQSRWLDDMSNGHKEDILTLATLKGHLLATADYHGTIIVWNLM---SGHVFF----------------KLIS--------PVAXXXXXXXX-----XXXXXSINKLLFLQSRAKNK--SSASLVASGPYGLVHFWNVKEGGILYGRFKGGTESGQSLTAMIACKDQDIDDKLLFIGDRFGFISVWDIENY----ANNKVETDCPELLRRWRAHVSSITSLDLVLQSQ--VLITSSDDCTVRVWTFEGEYVGTFGQTEMWDLTN 3034
            + K+R+  + T FNI +GI  FD+    N++ T G++  + LWNPYV SKP G+L GH+  ++ V    +  ++FS   DK +++WD+             H++     +C +                   K   F      DE H      G  +    +Q  +L  K     +    +H+  VTC  YN    QV++   GSTV  W + TG+K+ +F   H ++ ++ +  D+   RLLTG  DG V++W+F NG+C          L   +  AV+  +I    K I+  GW+RAI V+  Q     ++ +     W   +   H +DIL  A L    L T  Y G I++WN     + HV                  KL+S        P+AD             +   ++ +L FL++R        A+LV+ G  G V FW++ +  +L   F   +  G  + +       D  ++ L  GD  G++ +W+IE Y    + NK+ T  P L+R ++ H   I+SL++       ++I+SS DC++ V       V  FGQ + W + N
Sbjct:    6 KSKKRL--NMTSFNIAQGIHAFDYHSRLNLIATAGINNKVCLWNPYVVSKPVGVLWGHSASVIAVQFFVERKQLFSFSKDKVLRLWDIQ------------HQLSIQRIACSFP------------------KSQDFRCLFHFDEAH------GRLFISFNNQLALLAMKSEA--SKRVKSHEKAVTCVLYNSILKQVISSDTGSTVSFWMIDTGQKIKQFTGCHGNAEISTMALDANETRLLTGSTDGTVKIWDF-NGYC-------HHTLNVGQDGAVDISQILILKKKILVTGWERAITVFRPQ---NFNQFFIQPEEWKGGIQ--HHDDILCAAFLPPQTLVTGSYDGEIVLWNNSTENAHHVLHPDYQRLLKSKLDTKPQKLLSAGRSQPSHPMADHSTTGVRNFEIDTEGKNAVMRLCFLKARKNTAVTGGANLVSCGGSGYVRFWDIYKKQLL-AEFLAHSGVGSIIMST------DKMNRYLTTGDLDGWLKIWNIEEYCLNSSKNKI-TKAPTLIRSFQPHEDRISSLEMCEPGGQLLIISSSADCSICVTGVCNAPVWIFGQAKHWHIEN 524          

Query:  554 FEDIQTETLFKKIDWASSGAINWDEFCTYMQLEYAEKEETYLK-AREMAFCLPARIENTPHRENVIRITST-----------SDGSFIAGSTDGILSFWSNTLELKKCKSVVTIEQSQRVKSKWIIDFLIMNEFNKIIVATGDREIEFFEL--SSFEPYCRIHSLENVPLCLDYYVDKDNLDDCLILWGDRKGCVNILHLHATGECLRTWKKQP----RSEGIAGIGMENVL--SNPSIKFYRW-KVHNDWVLKLKYYDSLRQIISCSNDEATALVIGCVEGSTQLDQQMKLKSMHQTKSKDMTFGNMLQPKRRISTDQTVFNIYKGIQTFDFGKSKNVLVTGGLDRIIRLWNPYVNSKPTGMLRGHNKPLVYVHIAEQENRIFSICADKCVKVWDLHDHNCLLTVRPKGHRIRGDMQSC-HYSDFAKSLMIATDQVSMLNIKINPFVAEKQLDERHQRASYLGGCYFEQISQNTVLVNKPPVLHTDVAVTHKDPVTCCKYNEAFNQVVTCCEGSTVKLWNLSTGEKVFEFNEAH--------EDSGVTCLTFDSXXXXXXXXXXDGMVRMWNFNNGHCLTELKKEESDLKYAEISAVEYVEISRNKFIVSVGWDRAINVYIDQCEPGMHKSYYPQSRWLDDMSNGHKEDILTLATLKGH--LLATADYHGTIIVWNLMSGHVF--FKLISP------------------------------------VAXXXXXXXXXXXXXSINKLLFLQSRAKNKSSASLVASGPYGLVHFWNVKEGGILYGRFKGGTESGQSLTAMIACKDQDIDDKLLFIGDRFGFISVWDIE---NYANNKVE-------------------TDCPELLRRWRAHVSSITSLDLVLQSQVLITSSDDCTVRVWTFEGEYVGTFGQTEMW-----DLTNPKTFQHPMVP 3064
            F D + ETLF KI+        WDE  +Y+ L +   +   ++ + ++   L   ++       VI+I  +           S G +   + + +++FW    + +K     +++  +R K+ WI+D  ++ + N   VA  + E+  +++  S F     ++ + N    L Y+         ++  GD KG + ++  +         +K+P     +  +  +   ++L  S P ++   + ++  D V +L++ +     ++CS ++  A         ++      +   H TK   +                T   + KG+  F +   K+ LVTGG D  +R+W+      P   L GHN  +V++ + +   +I+S+   K VK+WD+ +   + T       +   + +C +Y+D  + L+I  ++V  L+    P                                 K P+  TD   +H  P++   YN  F  +++C   S + +W+ +   K+    +AH        E   +T   FD   + LLTG RDG +++WNFN+G C++ +  +E      E++AV +   S    I+++GW+ A+ V       GM    +P+     D    H +DIL  +        +AT  Y G I+ W + +G  +  F    P                                       +          L+I++LLFL+SR  +    +L++S   G++  ++    G   G F     +G  + +M      D  +K LF G   G++  W +E   N A  K++                      P LL  ++AH + IT+L  +  +++L+++S D T+R+W+  G Y+G  G    W     D+  PK +   + P
Sbjct:   64 FSDEEFETLFMKINTDRDNFCQWDELISYLILGFHNDDPLAVQESLDLPISLDMSVKLGRQTYPVIKIEYSPMVSYDGTVNWSQGFWATSTQEAVINFWKRDWKHEKTGKAFSVDL-KRAKT-WILDTAVLPDLNYFCVACLEHELRIYDIIGSGFTLKIIVNRIPNPINALKYHFSASTRSKLIM--GDYKGVLRVVEFYPE-------RKEPFKFDAASTVTRLSFRDLLNGSYPQMECVDYGRLLPDIVRQLQFVEPTYSFLACSENDPLA------PSGSRKKLYTSVIIQHLTKLDKI----------------TKIKVPKGVTCFAYDHVKDFLVTGGPDGELRMWDIRRPENPVASLSGHNAGVVFMFLQDGSQKIYSMDTKKIVKIWDVLNRILIQTYSQFSTTLYKTVPACAYYNDLNRELVIGANKV--LSAPCCP---------------------------------KIPLEVTD-GESHTQPISVLLYNPLFKVLISCGLDSYIIVWDHTMNRKLTIITDAHTQVVNGLLEQVQITAACFDPKLQLLLTGARDGTLKVWNFNSGSCMSSMSIQEG----CEVTAVFWEPTS----ILAMGWNHAV-VEFPVGTTGMD---FPRGI---DWQKLHSDDILCASVTHSEPKAIATCSYTGEIVFWLMETGQPYQRFNAAKPQQKIPVNAMTTKIGKPKRRSRMSVFMPQEQLRQRRLTRIVMPVKAEQLRQLTIHELLFLESRPMHPEVGTLLSSLDTGVIQVYSHHVDGGFLGSFNAVHMAGDRVVSMTT----DPYNKFLFTGSYLGYVKTWLLEASFNRAALKMQFPFLLDDIIPGRAKRSVANQPLPWLLNSYQAHRNCITALSYIPATKLLLSASSDHTIRIWSLAGRYIGLLGSPVKWATIDADVPIPKEYGFRIPP 909          

Query: 1442 DQTVFNIYKGIQTFDFGKSKNVLVTGGLDRIIRLWNPYVNSKPTGMLRGHNKPLVYVHIAEQENRIFSICADKCVKVWDLHDHNCLLTVRPKGHRIRGDMQS-----CHYSDFAKSLMIATDQVSMLNIKINPFVAEKQLDERHQRASYLGGCYFEQISQNTVLVNKPPVLHTDVAVTHKDPVTCCKYNEAFNQVVTCCEGSTVKLWNLSTGEKVFEFNEAHE--------DSGVTCLTFDSXXXXXXXXXXDGMVRMWNFNNGHCLTELKKEESDLKYAEISAVEYVEISRNKFIVSVGWDRAINVYIDQCEPGMHKSYYPQSRWLDDMSNGHKEDILTLATLKGHLLATADYHGTIIVWNLMSGHVF--FKLISPVAXXXXXXXX-------------------------------------XXXXXSINKLLFLQSRAKNKSSASLVASGPYGLVHFWNVKEGGILYGRFKGGTESGQSLTAMIACKDQDIDDKLLFIGDRFGFISVWDIENYANNKVETD--C-----------------------------PELLRRWRAHVSSITSLDLVLQSQVLITSSDDCTVRVWTFEGEYVGTFGQTEMWDLTNP 3037
            D+  F I  G+  F   +SKN+LVTGG D  +R+W+ Y++S+P+ +L GHN  +V V +  +EN+++S+   K +KVWDL +H  L T    G  +R    S      +Y    + L++A  +  ++ IK  P V     D                                    TH  PV+   YN  F  +VTC   S + +W+  TG +       H         D  +T   FD   + LLTG RDG +++WN+NN   +  +  +       E++AV +V I R   I+++GWDR +  + D       + Y    +W    +  H +DI       G  + TA Y G II W L +G  +  + +++P   ++   +                                       +  +S+  +LFLQ R   K   S+  S   G +  ++  + G    +F    + G  +  M +    D  ++ L+ G  FG+I +W I NY   + E    C                             P L+  ++ H+ +I S+  +   ++L T S D + R+WT  G Y+GT G    W    P
Sbjct:  326 DRNNFRIPLGVSVFYVAESKNILVTGGPDTFVRIWDVYISSEPSAILTGHNGGIVAVFVQPEENKVYSVDYHKVIKVWDLQEHTLLQTF---GELVRIIHHSETDIKYYYHSHLRDLLVAGRK--LIQIKCCPRVRVDLTDGN----------------------------------THAAPVSVVLYNRLFRNIVTCGLDSYIIVWDPWTGRRKIIMKNCHTKMIYGEIIDIEITAACFDPLEQFLLTGARDGSLKIWNYNNAVVVRNMSIQPDQ----EVTAVIWV-IDR---ILAMGWDRQVTEFNDVAG----REYGDPKKW----AKFHTDDITCADVKLGEGVVTATYSGEIIFWKLETGQPYRRYNVMNPYQFIELKLNTEEEKLTRRSKRISSLMGAGRRTLVLQNFKPDEIKDYGANIPVSVQAVLFLQKRPMTKDHGSVFISLDTGYIQVYSHHQHGGFIKQFFAVHKVGDCVLTMAS----DRKNRFLYTGTAFGYIKIWHIVNYCIPQAEKTEVCMPRLRLDFIFLRKDLFLTRAKRVIRNQPEPMLVSSYKGHLKAINSIGFINLPKILFTGSHDYSCRLWTQGGRYLGTLGTVLPWSKLTP 881          

Query: 1442 DQTVFNIYKGIQTFDFGKSKNVLVTGGLDRIIRLWNPYVNSKPTGMLRGHNKPLVYVHIAEQENRIFSICADKCVKVWDLHDHNCLLT----VRPKGHRIRGDMQSCHYSDFAKSLMIATDQVSMLNIKINPFVAEKQLDERHQRASYLGGCYFEQISQNTVLVNKPPVLHTDVAVTHKDPVTCCKYNEAFNQVVTCCEGSTVKLWNLSTGEKVFEFNEAHE--------DSGVTCLTFDSXXXXXXXXXXDGMVRMWNFNNGHCLTELKKEESDLKYAEISAVEYVEISRNKFIVSVGWDRAINVYIDQCEPGMHKSYYPQSRWLDDMSNGHKEDILTLATLKGHLLATADYHGTIIVWNLMSGHVF--FKLISP-------------------------------------VAXXXXXXXXXXXXXSINKLLFLQSRAKNKSSASLVASGPYGLVHFWNVKEGGILYGRFKGGTESGQSLTAMIACKDQDIDDKLLFIGDRFGFISVWDIENYANNKVETD--C-----------------------------PELLRRWRAHVSSITSLDLVLQSQVLITSSDDCTVRVWTFEGEYVGTFGQTEMWDLTNP 3037
            D+  F I  G+  F   + KN+LVTGG D  +R+W+ Y++S+P+ +L GHN  +V V +  +EN+++S+   K +KVWDL +H  L T    VR   H    D++  ++S   + LM+A  +  ++ IK  P V     D                                    TH  PV+   YN  F  +VTC   S + +W+  TG +       H         D  +T   FD   + LLTG RDG +++WN+NN   +  +  +       E++AV +V + R   I+++GWDR +  + D       + Y    +W    +  H +DI       G  + TA Y G II W L +G  +  + ++ P                                     +   +      +  +S+  +LFLQ R   K   S+  S   G++  ++  + G    +F    ++G  +  M      D  ++ L+ G  FG+I VW I NY   K E    C                             P L+  ++ H+ +I S+  +   +++ + S D + R+WT  G Y+GT G    W    P
Sbjct:  318 DRNNFRIPLGVSVFYVSEIKNILVTGGPDTFVRIWDVYISSEPSAILTGHNGGIVAVFVQPEENKVYSVDYHKIIKVWDLQEHTLLQTYGDLVRII-HHSETDIKYYYHSHL-RELMVAGRK--LIQIKCCPRVRVDLTDGN----------------------------------THAAPVSVVLYNRLFRNIVTCGLDSYIIVWDPWTGRRKIIMKNCHTKMIYGETIDIEITAACFDPLEQFLLTGARDGSLKIWNYNNAVVVRNMSIQPDQ----EVTAVIWV-VDR---ILAMGWDRQVTEFNDV----EGREYGDPKKW----AKFHTDDITCADVKLGEGVVTATYSGEIIFWKLETGQPYRRYNVMDPSRFIELKLNAEEEKLTRRSKRMSSLIGVNRRSTSVQAIKPDEIKDYGANIPVSVQAVLFLQRRPMTKEHGSVFISLDTGIIQVYSHHQHGGYIKQFTAVHKTGDCVLTMAT----DRKNRFLYTGTAFGYIKVWHIVNYCIPKAEQTYVCMPRLRLEFIFLRKELFLTRAKRMVRFQPEPMLVSSYKGHLKAINSIGFINLPKIIFSGSHDYSCRLWTQGGRYLGTLGTVLPWSKLTP 873          

Query: 1442 DQTVFNIYKGIQTFDFGKSKNVLVTGGLDRIIRLWNPYVNSKPTGMLRGHNKPLVYVHIAEQENRIFSICADKCVKVWDLHDHNCLLTVRPKGHRIRGDMQS-----CHYSDFAKSLMIATDQVSMLNIKINPFVAEKQLDERHQRASYLGGCYFEQISQNTVLVNKPPVLHTDVAVTHKDPVTCCKYNEAFNQVVTCCEGSTVKLWNLSTGEKVFEFNEAHE--------DSGVTCLTFDSXXXXXXXXXXDGMVRMWNFNNGHCLTELKKEESDLKYAEISAVEYVEISRNKFIVSVGWDRAINVYIDQCEPGMHKSYYPQSRWLDDMSNGHKEDILTLATLKGHLLATADYHGTIIVWNLMSGHVF--FKLISP-------------------------------------VAXXXXXXXXXXXXXSINKLLFLQSRAKNKSSASLVASGPYGLVHFWNVKEGGILYGRFKGGTESGQSLTAMIACKDQDIDDKLLFIGDRFGFISVWDIENYANNKVETD--C-----------------------------PELLRRWRAHVSSITSLDLVLQSQVLITSSDDCTVRVWTFEGEYVGTFGQTEMWDLTNP 3037
            D+  F I  G+  F   + KN+LVTGG D  +R+W+ Y++S+P+ +L GHN  +V V +  +EN+++S+   K +KVWDL +H  L T    G  +R    S      +Y    + LM+A  +  ++ +K  P V     D                                    TH  PV+   YN  F  +VTC   S + +W+  TG +       H         D  +T   FD   + LLTG RDG +++WN+NN   +  +  +       E++AV +V + R   I+++GWDR +  + D       + Y    +W    +  H +DI       G  + TA Y G II W L +G  +  + ++ P                                     +   +      +  +S+  +LFLQ R   K   S+  S   G++  ++  + G     F    + G  +  M      D  ++ L+ G  FG+I +W I NY   + E    C                             P L+  ++ H+ +I S+  +   ++L + S D + R+WT  G Y+GT G    W   +P
Sbjct:  318 DRNNFRIPLGVSVFYVSEVKNILVTGGPDTFVRIWDVYISSEPSAILTGHNGGIVAVFVQPEENKVYSVDYHKIIKVWDLQEHTLLQTY---GELVRIIHHSEMDIKYYYHSHLRELMVAGRK--LIQVKCCPRVRVDLTDGN----------------------------------THAAPVSVVLYNRLFRNIVTCGLDSYIIVWDPWTGRRKIIMKNCHTKMIYGETIDIEITAACFDPLEQFLLTGARDGSLKIWNYNNSVVVRNMSIQMDQ----EVTAVIWV-VDR---ILAMGWDRQVTEFNDV----EGREYGDPKKW----AKFHTDDITCADVKLGEGVVTATYSGEIIFWKLETGQPYRRYNVMDPSQFIELKLTAEEEKLSRRSKRISSLLGANRRSASMLAIKPDEIKDYGANIPVSVQAVLFLQKRPMTKDHGSVFISLDTGIIQVYSHHQHGGHIKEFIAVHKVGDCVLTMAT----DRKNRFLYTGTAFGYIKIWHIVNYCIPEAEKTHVCMPKLRLDFIFLRKELFLTRAKRMVRNQPEPMLVSSYKGHLKAINSIGFINLPKILFSGSHDYSCRLWTQSGRYLGTLGTVLPWSKLSP 873          

Query:   50 TFKMSSVRVPIGGPVIKPSKIKIRPSSASGNIQTHQSYTTGLYDKKCLFLKDKIKESLPDSNKL--KKAGTHIGFLKE--SQRIIEPKDEIRKPRRRTIEIVDGMDITKFIGREMSLSLRK-HNLLDKIEERIDLTVLEELKAAFENAEYDRSGKLDLSEFKALLKEKLQLPTFEDIQTETLFKKIDWASSGAINWDEFCTYMQLEYAEKEETYLKAREMAFCLPARIENTPHRENVIRITSTSDGSFIAGSTDGILSFWSNTLELKKCKSVVTIE-QSQRVKSKWIIDFLIMNEFNKIIVATGDREIEFFELSSFEPYCRIHSLENVPLCLDYYVDKDNLDDCLILWGDRKGCVNILHLHATGECLRTWKKQPRSEG-IAGIGMENVLSNPSIKFYRWKVHNDWVLKLKYYDSLRQIISCSNDEATALVIGCVEGSTQLDQQMK-LKSMHQTKSKDMTFGNMLQPKRRISTDQTVFNIYKGIQTFDFGKSKNVLVTGGLDRIIRLWNPYVNSKPTGMLRGHNKPLVYVHIAEQENRIFSICADKCVKVWDLHDHNCLLTVRPKGHRIRGDMQSCHYSDFAKSLMIATDQVSMLNIKINPFVAEKQLDERHQRASYLGGCYFEQISQNTVLVNKPPVLHTDVAVTHKDPVTCCKYNEAFNQVVTCCEGSTVKLWNLSTGEKVFEFNEAHEDSGVTCLTFDSXXXXXXXXXXDGMVRMWNFNNGHCLTELKK--EESDLKYAEISAVEYVEISRNKFIVSVGWDRAINVYIDQC-EPGMHKSYYPQSRWLDDMSNGHKEDILTLATLKGHLLATADYHGTIIVWNLMSGHVFFKLISPVAXXXXXXXXXXXXXSINKLLFLQSRAKNKSSASLVASGPYGLVHFWNVKEGGILYGRFKGGTESGQSLTAMIACKDQDIDDKLLFIGDRFGFISVWDIENYANNKVETDCPELLRRWRAHVSSITSLDLVLQSQVLITSSDDCTVRVWTFEGEYVGTFGQTEMWDLTNPKTFQHPMVPYDVLVHPQSLPDHPVLGPRMTIEQRKEQSKAESTHKAKMTKQHALQSENSTFTHKNVIYIDDEEINQQIEQKIYKEGKGKRLRFERMKPRNALSEDGGPNEYRSLQVFELAKTPSPRQP 3421
            + KM S R       + P K +IRP+SAS N+QTH SYTTGLYD     L+     SL   N+   ++  T  G  +E  S R ++  + ++ PRR T+  V+G+     I R  ++ +     L DKIEE+I++  LEELK+AF +A+ +R+G LDL EFK LLKE+L L   +D Q ++LF KIDW+S GAI+WDEFCTYMQLEYAEKE++YL+A+E++F LPA+IE+ PHR+ V+RIT TSDG+FIA S +G ++FWS+  ELK+ +SVV  +  S R KSKWI DF +M  FNK+IV TGDREI+FFELSSF+PYC+I+ LE VPL LDY       D+CLIL+GD  GCVNI  + + GECLRTWKK    +G IA I ++ V+S  ++ F RW+VH DWV ++KYY  + Q+ISCSN  +TALVIG   GST ++QQ++ +K ++ ++ K+         K+R+  D+TVF +YKG++ FDF K+KNV+VTGG+DRIIRLWNPYV+ KPT MLRGH  P+ Y+ IAE++NRI+SI  D+C++VWD+ DH CLLT+RPK H+IRGD+Q+ +YS+ ++SL +ATDQ++++N+K             H+ +                       L+ D+ V+HKDPVTCCKYN  F Q+VTCC GS VKLW+  TG  +FE+ EAH +  +TC+TFD+T RRL+TGGRDG +++WN+NNGHCL  LKK  +++++   EI  V Y+E+++N+++++VGWD+ IN+Y D   +  +    +P   WLDD+ NGHKED+L++A    +LLAT  Y G +IVWN++SGH+F  L  P      +   +D D++I KL+FLQ+RA  K + +LV SGP   +H WNV +GG L  +F+G +  G  ++ +++    +  + +L+  D  GFI  W++ +Y   +   + PELL +WR HV S+ S+DLV  + VL+TSS DCTVR+WT +G Y+GT GQ+E WDL NP TFQHPMVPY+VL+ P SLP HPVL         ++QS  +  H+    K     S    F  K    +DDE+I   +E++ + +G GKRLR E+ K      E  G + ++ +   +L   P    P
Sbjct:    4 SVKMPSNREISPFSPLPPIKKRIRPTSASANLQTHPSYTTGLYDN---VLR---TSSLATGNQTIKQRPHTQAGGPREQNSYRPVDTHENVKHPRRLTLGTVEGIAELDSILRVGNIQISAAQQLKDKIEEKINIDTLEELKSAFMSADVNRTGSLDLEEFKKLLKEQLGLGPSKDAQIDSLFMKIDWSSEGAISWDEFCTYMQLEYAEKEDSYLRAKEVSFHLPAKIESIPHRDLVLRITDTSDGTFIACSQEGTVTFWSSNTELKRTRSVVNQDIMSNRTKSKWITDFCLMPHFNKLIVGTGDREIQFFELSSFDPYCQIYGLETVPLKLDY--SSTGHDECLILFGDNVGCVNIFVIKSAGECLRTWKKMTVPDGFIATIHLDAVISGFNVNFIRWQVHEDWVGQIKYYHDIGQVISCSNHPSTALVIGSTTGSTHVEQQLREIKDVNYSQEKNKQKAAYNIVKKRLGADETVFKVYKGVKVFDFSKAKNVIVTGGMDRIIRLWNPYVSLKPTAMLRGHAAPIFYLTIAEEDNRIYSISTDRCIRVWDIQDHTCLLTIRPKSHKIRGDLQAVYYSNISRSLAVATDQMAIMNLK-------------HKSS-----------------------LNADMVVSHKDPVTCCKYNPEFKQIVTCCCGSIVKLWDFETGSLIFEYGEAHGEEAITCMTFDNTKRRLITGGRDGSLKIWNYNNGHCLRVLKKKAKKNNVHTDEICDVTYIEMNKNRYVIAVGWDKRINIYYDTVNDTNIQYVQHPTPYWLDDLKNGHKEDVLSIAHCLPNLLATGSYDGEVIVWNMVSGHIFCHL-RPPPPPGYEDQNLDGDMNIAKLIFLQTRASKKDAGALVVSGPRAHIHIWNVSQGGTLMAQFQGSSIKGSMVSQLVS----NSANTVLYSSDTSGFIYAWNLTDYCLTRPAHEPPELLYKWRGHVESVASMDLVESNNVLVTSSSDCTVRLWTHQGHYIGTLGQSEQWDLYNPSTFQHPMVPYEVLIDPLSLPSHPVL--------LEKQSTHDIIHQGDEDKSLRSVSPQVVFNTKQSYVVDDEKIKALLEERPFDKGTGKRLRHEKHK--KMRDESSGTSVWQEISCHQLQDPPKRESP 1079          

Query:  107 KIKIRPSSASGNIQTHQSYTTGLYDKKCLFLKDKIKESLPDSNKLKKAG----THIGFLKESQRIIEPKDE-----IRKPRRRTIEIVDGMDITKFIGR-EMSLSLRKHNLLDKIEERIDLTVLEELKAAFENAEYDRSGKLDLSEFKALLKEKLQLPTFEDIQTETLFKKIDWASSGAINWDEFCTYMQLEYAEKEETYLKAREMAFCLPARIENTPHRENVIRITSTSDGSFIAGSTDGILSFWSNTLELKKCKSVVTIEQSQRVKSKWIIDFLIMNEFNKIIVATGDREIEFFELSSFEPYCRIHSLENVPLCLDYYVDKDNLDDCLILWGDRKGCVNILHLHATGECLRTWKKQPRSEGIAGIGMENVLSNPSIKFYRWKVHNDWVLKLKYYDSLRQIISCSNDEATALVIGCVEGSTQLDQQMKLKSMHQTKSKDMTFGNMLQPKRRISTDQTVFNIYKGIQTFDFGKSKNVLVTGGLDRIIRLWNPYVNSKPTGMLRGHNKPLVYVHIAEQENRIFSICADKCVKVWDLHDHNCLLTVRPKGHRIRGDMQSCHYSDFAKSLMIATDQ-VSMLNIKINPFVAEKQLDERHQRASYLGGCYFEQISQNTVLVNKPPVLHTDVAVTHKDPVTCCKYNEAFNQVVTCCEGSTVKLWNLSTGEKVFEFNEAHEDSGVTCLTFDSXXXXXXXXXXDGMVRMWNFNNGHCLTELKKEESDLKYAEISAVEYVEISRNKFIVSVGWDRAINVYID--QCEPGMHKSYYPQSRWLDDMSNGHKEDILTLATLKGHLLATADYHGTIIVWNLMSGHVFFKLISPVAXXXXXXXXXXXXXSINKLLFLQSRAKNKSSASLVASGPYGLVHFWNVKEGGILYGRFKGGTESGQSLTAMIACKDQDIDDKLLFIGDRFGFISVWDIENYANNKVETDCPELLRRWRAHVSSITSLDLVLQSQVLITSSDDCTVRVWTFEGEYVGTFGQTEMWDLTNPKTFQHPMVPYDVLVHPQSLPDHPVLGP-RMTIEQRKEQSKAESTHKAKMTKQHALQSENSTFTHKNVIY---------IDDEEINQQIEQKIYKEGKGKRLRFERMKPRNALSEDGGPNEYRSLQVFELAKTPSPRQPE 3424
            K KIRPSSA+  +Q+H S+ T ++D       +    +   S +  +AG    TH    +   R   P+DE      ++PRR T+  VDG+   + I R  M        L  KIEE+I+L  LE LK AF  A+ D SG+L+L EFKALLKE+L L    D Q ++LF KIDW+S GAI WDEFCTYMQLEYAEKE++YL+++++AF LPA+I N   RE+++RIT TSDG+F+A S DG +SF    +++KK K ++  E   + K KWI DF+IMNEFNK +V TGDREI+F+ELSS +PYC++  L+ VPL LDY       D+CLIL+GD  GC+NIL +++ GECLRTWKK P+ +GIA + +++V+    +++ RW+VH DWV +LKYY ++ QIISCSN+  TALVIGC  GST ++ Q+K     + +++     N+ +P  R+  DQ+VF +YKG++ FDF K+KNV+VTGG+DRI+RLWNPYV  KPT +LRGHN P+ Y+ IAE+E+RIFSI  DKCVK+WD+ DHNCLLT+RPK H+I GD+Q+CHYS+ AKSL +ATDQ ++ LN++                                    + PVLH D+ +THK+PVTCCKYN +FNQV+TC EGS +KLW+  +G  +FEF +AH ++ +TC+TFDSTGRRLLTGGRDG +++WN+NNGHCL  LKK   D +  E+  + YVE++RN++++SVGWDR IN+Y D    +  +H    P   W DD  NGHKEDIL +A    +L+AT  Y G +IVWN++SGH+F  L + V   + + + +D D+S+NKL+FL+SR   K+SASL+ASGP+G +HFWNV +GG +  +FKG   SG  +T M      D  + +LF GD  GFI ++D++ Y  N      P L+  WR HV S+ +L++V +++V++T+S DCTVR+WTF  +Y+GT+GQ E WDL +P TFQHPMVPYDVL+ P SLP HP+      T +  K+ +K E       T Q  LQ +N  F   + I          + DE++N++  QK     +GK LR E+ K +   ++ GGPNEY  L+   L  TP P  P+
Sbjct:   86 KKKIRPSSAAAKLQSHPSFYTNIFD-------NSRPATATTSTRSPEAGQRPVTHAAGGRRQYRA-PPEDERLKEIAKQPRRLTLGAVDGISELEHIPRPSMGNGAISAQLKSKIEEQINLDTLEILKQAFVEADEDGSGELELDEFKALLKERLHLKGTNDAQIDSLFMKIDWSSDGAITWDEFCTYMQLEYAEKEDSYLRSKDVAFHLPAKIINC--RESILRITDTSDGTFVACSLDGNVSFMGTNMDIKKHKCLINNEPGLKQKQKWITDFVIMNEFNKFLVGTGDREIQFYELSSLDPYCQVSGLDTVPLKLDYC--STGTDECLILYGDSLGCINILLVNSAGECLRTWKKAPKHDGIASVSLDSVIKVQKVQYLRWQVHGDWVQQLKYYHNIGQIISCSNNANTALVIGCTTGSTHVEAQLKETKDPEDRARRT---NVAKP--RLEADQSVFYVYKGVKCFDFCKNKNVIVTGGMDRIVRLWNPYVPGKPTALLRGHNAPIFYLFIAEEESRIFSISTDKCVKIWDIQDHNCLLTIRPKAHKIHGDLQACHYSNIAKSLAVATDQKLAALNLR------------------------------------QKPVLHADITITHKEPVTCCKYNPSFNQVITCSEGSVIKLWDFESGAGIFEFGDAHGEAAITCMTFDSTGRRLLTGGRDGTIKIWNYNNGHCLRMLKK---DAETDEVCDLTYVEMNRNRYVISVGWDRTINIYSDDANADSNIHLVQNPNLFWADDKKNGHKEDILAIAQSPPNLIATGSYDGEVIVWNMVSGHIFCHLRAAVP-PNYEDESLDGDMSVNKLVFLKSRESRKASASLIASGPHGHIHFWNVFQGGSMMAQFKGSKSSGGMITTMAT----DDANTMLFCGDSLGFILIYDVDGYCLNGKTKAPPTLIHSWRGHVDSVLNLEMVEKNKVILTASMDCTVRMWTFNSDYIGTYGQPEPWDLYDPSTFQHPMVPYDVLIDPMSLPPHPIFDQISETPDLLKDTTKTEDAPVRTPTPQ-VLQGKNQFFVDDDTIARQLKDLSGTLKDEKLNEEEIQKF----RGKWLRHEKTKIKP--TDRGGPNEYHMLKWSPLKDTPMPPPPK 1146          

Query:   50 TFKMSSVRVPIGGPVIKPSKIKIRPSSASGNIQTHQSYTTGLYDKKCLFLKDKIKESLPDSNKLKKAGTHI--GFLKE--SQRIIEPKDEIRKPRRRTIEIVDGMDITKFIGREMSLSLRK-HNLLDKIEERIDLTVLEELKAAFENAEYDRSGKLDLSEFKALLKEKLQLPTFEDIQTETLFKKIDWASSGAINWDEFCTYMQLEYAEKEETYLKAREMAFCLPARIENTPHRENVIRITSTSDGSFIAGSTDGILSFWSNTLELKKCKSVVTIE-QSQRVKSKWIIDFLIMNEFNKIIVATGDREIEFFELSSFEPYCRIHSLENVPLCLDYYVDKDNLDDCLILWGDRKGCVNILHLHATGECLRTWKKQPRSEG-IAGIGMENVLSNPSIKFYRWKVHNDWVLKLKYYDSLRQIISCSNDEATALVIGCVEGSTQLDQQMK-LKSMHQTKSKDMTFGNMLQPKRRISTDQTVFNIYKGIQTFDFGKSKNVLVTGGLDRIIRLWNPYVNSKPTGMLRGHNKPLVYVHIAEQENRIFSICADKCVKVWDLHDHNCLLTVRPKGHRIRGDMQSCHYSDFAKSLMIATDQVSMLNIKINPFVAEKQLDERHQRASYLGGCYFEQISQNTVLVNKPPVLHTDVAVTHKDPVTCCKYNEAFNQVVTCCEGSTVKLWNLSTGEKVFEFNEAHEDSGVTCLTFDSXXXXXXXXXXDGMVRMWNFNNGHCLTELKKEESDLKYA---EISAVEYVEISRNKFIVSVGWDRAINVYIDQC-EPGMHKSYYPQSRWLDDMSNGHKEDILTLATLKGHLLATADYHGTIIVWNLMSGHVFFKLISPVAXXXXXXXXXXXXXSINKLLFLQSRAKNKSSASLVASGPYGLVHFWNVKEGGILYGRFKGGTESGQSLTAMIACKDQDIDDKLLFIGDRFGFISVWDIENYANNKVETDCPELLRRWRAHVSSITSLDLVLQSQVLITSSDDCTVRVWTFEGEYVGTFGQTEMWDLTNPKTFQHPMVPYDVLVHPQSLPDHPVLGPRMTIEQRKEQSKAESTHKAKMTKQHALQSENSTFTHKNVIYIDDEEINQQIEQKIYKEGKGKRLRFERMKPRNALSEDGGPNEYRSLQVFELAKTPSPRQP 3421
            + KM S R       + P K +IRP+SAS N+QTH SYTTGLYD     L+     SL   N+  K   H   G  +E  S R ++  + ++ PRR T+  V+G+     I R  ++ +     L DKIEE+I++  LEELK+AF +A+ +R+G LDL EFK LLKE+L L   +D Q ++LF KIDW+S GAI+WDEFCTYMQLEYAEKE++YL+A+E++F LPA+IE+ PHR+ V+RIT TSDG+FIA S +G ++FWS+  ELK+ +SVV  +  S R KSKWI DF +M  FNK+IV TGDREI+FFELSSF+PYC+I+ LE VPL LDY       D+CLIL+GD  GCVNI  + + GECLRTWKK    +G IA I ++ V+S  ++ F RW+VH DWV ++KYY  + Q+ISCSN  +TALVIG   GST ++QQ++ +K ++ ++ K+         K+R+  D+TVF +YKG++ FDF K+KNV+VTGG+DRIIRLWNPYV+ KPT MLRGH  P+ Y+ IAE++NRI+SI  D+C++VWD+ DH CLLT+RPK H+IRGD+Q+ +YS+ ++SL +ATDQ++++N+K             H+ +                       L+ D+ V+HKDPVTCCKYN  F Q+VTCC GS VKLW+  TG  +FE+ EAH +  +TC+TFD+T RRL+TGGRDG +++WN+NNGHCL  LKK+          EI  V Y+E+++N+++++VGWD+ IN+Y D   +  +    +P   WLDD+ NGHKED+L++A    +LLAT  Y G +IVWN++SGH+F  L  P      +   +D D++I KL+FLQ+RA  K + +LV SGP   +H WNV +GG L  +F+G +  G  ++ +++    +  + +L+  D  GFI  W++ +Y   +   + PELL +WR HV S+ S+DLV  + VL+TSS DCTVR+WT +G Y+GT GQ+E WDL NP TFQHPMVPY+VL+ P SLP HPVL         ++QS  +  H+    K     S    F  K    +DDE+I   +E++ + +G GKRLR E+ K      E  G + ++ +   +L   P    P
Sbjct:    4 SVKMPSNREISPFSPLPPIKKRIRPTSASANLQTHPSYTTGLYDN---VLR---TSSLATGNQTIKQRPHTQAGGPREQNSYRPVDTHENVKHPRRLTLGTVEGIAELDSILRVGNIQISAAQQLKDKIEEKINIDTLEELKSAFMSADVNRTGSLDLEEFKKLLKEQLGLGPSKDAQIDSLFMKIDWSSEGAISWDEFCTYMQLEYAEKEDSYLRAKEVSFHLPAKIESIPHRDLVLRITDTSDGTFIACSQEGTVTFWSSNTELKRTRSVVNQDIMSNRTKSKWITDFCLMPHFNKLIVGTGDREIQFFELSSFDPYCQIYGLETVPLKLDY--SSTGHDECLILFGDNVGCVNIFVIKSAGECLRTWKKMTVPDGFIATIHLDAVISGFNVNFIRWQVHEDWVGQIKYYHDIGQVISCSNHPSTALVIGSTTGSTHVEQQLREIKDVNYSQEKNKQKAAYNIVKKRLGADETVFKVYKGVKVFDFSKAKNVIVTGGMDRIIRLWNPYVSLKPTAMLRGHAAPIFYLTIAEEDNRIYSISTDRCIRVWDIQDHTCLLTIRPKSHKIRGDLQAVYYSNISRSLAVATDQMAIMNLK-------------HKSS-----------------------LNADMVVSHKDPVTCCKYNPEFKQIVTCCCGSIVKLWDFETGSLIFEYGEAHGEEAITCMTFDNTKRRLITGGRDGSLKIWNYNNGHCLRVLKKKAKKNNAVHTDEICDVTYIEMNKNRYVIAVGWDKRINIYYDTVNDTNIQYVQHPTPYWLDDLKNGHKEDVLSIAHCLPNLLATGSYDGEVIVWNMVSGHIFCHL-RPPPPPGYEDQNLDGDMNIAKLIFLQTRASKKDAGALVVSGPRAHIHIWNVSQGGTLMAQFQGSSIKGSMVSQLVS----NSANTVLYSSDTSGFIYAWNLTDYCLTRPAHEPPELLYKWRGHVESVASMDLVESNNVLVTSSSDCTVRLWTHQGHYIGTLGQSEQWDLYNPSTFQHPMVPYEVLIDPLSLPSHPVL--------LEKQSTHDIIHQGDEDKSLRSVSPQVVFNTKQSYVVDDEKIKALLEERPFDKGTGKRLRHEKHK--KMRDESSGTSVWQEISCHQLQDPPKRESP 1080          

Query:  389 SLRKHNLLDKIEERIDLTVLEELKAAFENAEYDRSGKLDLSEFKALLKEKLQLPTFEDIQTETLFKKIDWASSGAINWDEFCTYMQLEYAEKEETYLKAREMAFCLPARIENTPHRENVIRITSTSDGSFIAGSTDGILSFWSNTLELKKCKSVVTIEQSQRVKSKWIIDFLIMNEFNKIIVATGDREIEFFELSSFEPYCRIHSLENVPLCLDYYVDKDNLDDCLILWGDRKGCVNILHLHATGECLRTWKKQPRSEGIAGIGMENVLSNPSIKFYRWKVHNDWVLKLKYYDSLRQIISCSNDEATALVIGCVEGSTQLDQQMKLKSMHQT------KSKDMTFGNMLQPKRRISTDQTVFNIYKGIQTFDFGKSKNVLVTGGLDRIIRLWNPYVNSKPTGMLRGHNKPLVYVHIAEQENRIFSICADKCVKVWDLHDHNCLLTVRPKGHRIRGDMQSCHYSDFAKSLMIATDQVSMLNIKINPFVAEKQLDERHQRASYLGGCYFEQISQNTVLVNKPPVLHTDVAVTHKDPVTCCKYNEAFNQVVTCCEGSTVKLWNLSTGEKVFEFNEAHEDSGVTCLTFDSXXXXXXXXXXDGMVRMWNFNNGHCLTELKKEESDLKYAEISAVEYVEISRN---------------KFIVSVGWDRAINVY-IDQCEPGMHKSYYPQSRWLDDMSNGHKEDILTLATLKGHLLATADYHGTIIVWNLMSGHVFFKLISPVAXXXXXXXXXXXXXSINKLLFLQSRAKNKSSASLVASGPYGLVHFWNVKEGGILYGRFKGGTESGQSLTAMIACKDQDIDDKLLFIGDRFGFISVWDIENYANNKVETDCPELLRRWRAHVSSITSLDLVLQSQVLITSSDDCTVRVWTFEGEYVGTFGQTEMWDLTNPKTFQHPMVPYDVLVHPQSLPDHPVLGPRMTIEQRKEQSKAESTHKAKMTKQHALQSENSTFTHKNVIYIDDEEINQQIEQKIYKEGKGKRLRFERMKPRNALSEDGGPNEYRSLQVFELAKTPSPRQPEI 3427
            +L +  L  KIEE+I++  L  LK AFE A+ D SG+LDL EFK LLK KL+L   ++ Q + LF KID++S G I WDEFCTYMQLEYAEKE++Y + ++++F LPARIE TPHR+ V++IT  SDG+ +A S DG +SFW+  L+LK+ +S+V  + + + K KWI D ++M +FNKIIV TGDREI+F+ELSSFEPYC+I  LE VPL +DY       D+CLIL+GD  GC+NIL +  TGECLR WKK P+ EGIA +G+E V      KF RWKVH DWV ++KYYD + Q+ISCSN   TALVIGC  GST +DQQ+K      T      K K+ T      PK R+ +DQ VF +YKG++TF F K KN LVTGG+DRI+R+WNPYV +KPTGMLRGHN P+ Y+ ++E+++RIFSI  DKCVKVWD+ D NCL+TVRPK H+IRGD+QSC+YS   K L++ATDQ+S+L IK                                      P+L  ++ +TH+DPV   +YN  F Q++TC   STVKLW+  +G  +F+F+ AH D+ +TCL FD+TGRR +TG RDG +++WN+NNGHCL  L KE  +    EI +  Y+E+++N               +++VSVGWD  +N+Y  DQ +  +  +  PQ  W DD+ NGHKEDIL++A    +LLAT+ Y G +IVWN++SGH+F  L +PV         +D DLSINKLLFL+SRA  K +ASL+A GP G +HFWNV  GG LY +F G   +G  +TAM   K    +D +LF  D  GFI  W++E Y      TD PEL+  WR HV SIT++D++ + +++I+SS DCTVR+WT EG YVGT GQ + WD+ NP TFQHPMVPYDVLV P+SLP HPV+  ++ +E+     K +   + K+        + S F       +DD  I +QI+QK + +G GKR+R ERMK R    +  GP+EYR LQ F L +TP  + PEI
Sbjct:   71 ALAEDALKKKIEEKINIDTLNLLKQAFEEADEDGSGELDLDEFKVLLKSKLKLEGTKEQQIDALFYKIDYSSDGLITWDEFCTYMQLEYAEKEDSYRRLKDVSFQLPARIETTPHRDTVLKITDASDGTILACSQDGTVSFWNGNLDLKRVRSIVPNDPAMKPKQKWITDMVLMPQFNKIIVVTGDREIQFYELSSFEPYCQISGLETVPLKIDYC--GTGPDECLILYGDSIGCINILSIENTGECLRLWKKMPKVEGIATVGIEAVAGGGMTKFIRWKVHGDWVQEVKYYDEIGQVISCSNHSQTALVIGCTSGSTNVDQQLKDTKDSNTLVDNSSKGKNKTNTAYAVPKERLPSDQHVFRVYKGVKTFAFSKDKNTLVTGGMDRIVRMWNPYVPAKPTGMLRGHNAPIFYLFVSEEDDRIFSISTDKCVKVWDIQDQNCLVTVRPKSHKIRGDLQSCYYSAPNKCLVVATDQISLLAIKSR------------------------------------PILQAEIVLTHRDPVHTARYNPQFKQIITCSAASTVKLWDFESGNPIFDFSNAHGDAAITCLCFDNTGRRCITGARDGCLKIWNYNNGHCLRVLMKESGN---DEICSCAYIEMNKNRKLLDVNTEIEIRPQRYVVSVGWDHRVNIYSDDQDDDDVRHTIDPQPPWQDDLENGHKEDILSVAFCPPNLLATSSYDGEVIVWNMVSGHIFCHLFAPVP-KGYKDQSLDGDLSINKLLFLRSRAYKKDAASLIAGGPRGYLHFWNVFHGGSLYAQFTGTKHTGAMVTAMELYK----NDTILFTADSVGFIYCWNVEGYCAKSKATDSPELITYWRGHVESITNIDVIEEHKMMISSSLDCTVRLWTIEGHYVGTLGQPDPWDVFNPNTFQHPMVPYDVLVDPKSLPSHPVIAGKLNLEEVLHGDKKKDKVEEKIPPAPVYGEQTSYF-------VDDATIAEQIKQKPFNKGTGKRVRHERMKARQMKIDRDGPSEYRLLQTFPLVETPDIKPPEI 1052          

Query:  416 KIEERIDLTVLEELKAAFENAEYDRSGKLDLSEFKALLKEKLQLPTFEDIQTETLFKKIDWASSGAINWDEFCTYMQLEYAEKEETYLKAREMAFCLPARIENTPHRENVIRITSTSDGSFIAGSTDGILSFWSNTLELKKCKSVVTIEQSQRVKSKWIIDFLIMNEFNKIIVATGDREIEFFELSSFEPYCRIHSLENVPLCLDYYVDKDNLDDCLILWGDRKGCVNILHLHATGECLRTWKKQPRSEG-IAGIGMENVLSNPSIKFYRWKVHNDWVLKLKYYDSLRQIISCSNDEATALVIGCVEGSTQLDQQMK-LKSMH-QTKSKDMTFGNMLQPKRRISTDQTVFNIYKGIQTFDFGKSKNVLVTGGLDRIIRLWNPYVNSKPTGMLRGHNKPLVYVHIAEQENRIFSICADKCVKVWDLHDHNCLLTVRPKGHRIRGDMQSCHYSDFAKSLMIATDQVSMLNIKINPFVAEKQLDERHQRASYLGGCYFEQISQNTVLVNKPPVLHTDVAVTHKDPVTCCKYNEAFNQVVTCCEGSTVKLWNLSTGEKVFEFNEAHEDSGVTCLTFDSXXXXXXXXXXDGMVRMWNFNNGHCLTELKKE-------ESDLKYAEISAVEYVEISRNKFIVSVGWDRAINVYIDQ-CEPGMHKSYYPQSRWLDDMSNGHKEDILTLATLKGHLLATADYHGTIIVWNLMSGHVFFKLISPVAXXXXXXXXXXXXXSINKLLFLQSRAKNKSSASLVASGPYGLVHFWNVKEGGILYGRFKGGTESGQSLTAMIACKDQDIDDKLLFIGDRFGFISVWDIENYANNKVETDCPELLRRWRAHVSSITSLDLVLQSQVLITSSDDCTVRVWTFEGEYVGTFGQTEMWDLTNPKTFQHPMVPYDVLVHPQSLPDHPVLGPRMTIEQRKEQSKAESTHKA------KMTKQHALQSENSTFTHKNVIYIDDEEINQQIEQKIYKEGKGKRLRFERMK 3328
            +IEE+I++  LE LK AF  A+ + SG+L+L EFK LLK +L LP   + Q + LF KIDW+S G+I WDEFCTYMQLEYAEKE++YL+A+E+ F  PARIEN PHR+ ++RIT TSDG+FIA S +G ++FWS++ ELK+ + VV  E + R K KWI DF+IM+ FNKIIV TGDREI+FFELSSFEPYC+I  L+ VPL LDY       D+CLIL+GD +GCVNIL + + GECLR   K    EG IA IG++ V + P+++F RW+VH+DWV ++KYY  + Q+ISCSN+   ALVIGC  GST ++QQ+K L+ +    K++  T+      K R+  DQ VF +YKG++ FDF K KN+++TGG+DRIIRLWNPYV+ KPT MLRGHN P+ ++HIA+Q++RI+S+  D+C+KVWD+ D  CLLTVRPK HRIRGD+Q+ HYS  ++++ +ATDQ+++L +             RH+ +++L                       D+ ++HKDPVTCCKYN +F QVVTCC GS VKLW+L TG  +FE+ +AH+ S +TC+TFD+T RRL+TGGRDG++++WN+NNGHCL  LKK+       E D    EI  + YVE+++N++++SVGWDR IN+Y D   +  +H   +P   W DD  +GHKED+L +A    +LLATA Y G IIVWN++SGH+F  L  P +    +   +D DL I++LLFL++RA  K + SLVASGP G +H W+V +GG L  +F G    G S++AM+  K     + +L+  D  GF+ VWDI  Y   K     PE++  WR HV  IT L+LV Q +VL++SS DCTVR+WTF+G Y+GTFGQ   WD+ NP T+QHPMVPYDVLV P SLP HPV+  R            ESTH+       K  +   + S    +  K   +I DE+I+  ++++ + +  GKRLR E+ K
Sbjct:  271 EIEEKINIDTLETLKQAFAAADRNHSGELELDEFKKLLKAQLHLPPNRENQIDALFMKIDWSSEGSITWDEFCTYMQLEYAEKEDSYLRAKEVVFQTPARIENIPHRDPILRITGTSDGTFIACSHEGYVTFWSSSAELKRTRCVVNTESTSRTKPKWITDFVIMSHFNKIIVGTGDREIQFFELSSFEPYCQISGLDTVPLKLDY--SSTGYDECLILYGDTQGCVNILIIKSAGECLRQMVKH---EGFIASIGLDAVANGPNVQFIRWQVHDDWVQQIKYYHEIGQVISCSNNPNKALVIGCTVGSTHVEQQLKELRDLGCAEKARSKTYYAYNNTKTRLEADQAVFKVYKGVKCFDFSKDKNIIITGGMDRIIRLWNPYVSHKPTAMLRGHNAPIFFLHIADQDDRIYSLSTDRCLKVWDIQDQTCLLTVRPKSHRIRGDLQAVHYSPVSRAIAVATDQMAVLCL-------------RHKSSTHL-----------------------DIVMSHKDPVTCCKYNSSFKQVVTCCSGSVVKLWDLETGAPIFEYGDAHDGSAITCMTFDNTLRRLITGGRDGVLKIWNYNNGHCLRTLKKKTENTDFNEQDSSQNEICDLTYVEMNKNRYVISVGWDRRINIYYDSVADSNIHHVQHPVPYWADDERDGHKEDVLAIAHCLPNLLATASYDGEIIVWNIVSGHIFCHL-RPPSPPGYEDQSLDGDLGISRLLFLKTRAYKKDAGSLVASGPRGHIHIWSVFQGGQLLAQFPGSKVPGASVSAMVTNK----VNTVLYTADSLGFVYVWDISTYCLEKSADGPPEVIATWRGHVEHITCLELVEQHKVLLSSSVDCTVRIWTFDGHYIGTFGQPVPWDVYNPATYQHPMVPYDVLVDPMSLPVHPVIAQR------------ESTHEVIHLDSKKDGEDKRIPSPPPQYGSKQQFFISDEQISAMLKERPFDKATGKRLRHEKNK 1200          

Query:  119 RPSSASGNIQTHQSYTTGLYDKKCLFLKDKIKESLPDSNKLKKAGTHIGFLKESQRIIEPKDEIRKP------RRRTIEIVDGMDITKFIGREMSLSLRKHNLLD-KIEERIDLTVLEELKAAFENAEYDRSGKLDLSEFKALLKEKLQLPTFEDIQTETLFKKIDWASSGAINWDEFCTYMQLEYAEKEETYLKAREMAFCLPARIENTPHRENVIRITSTSDGSFIAGSTDGILSFWSNTLELKKCKSVVTIEQSQRVKSKWIIDFLIMNEFNKIIVATGDREIEFFELSSFEPYCRIHSLENVPLCLDYYVDKDNLDDCLILWGDRKGCVNILHLHATGECLRTWKKQPRSEGIAGIGMENVLSNPSIKFYRWKVHNDWVLKLKYYDSLRQIISCSNDEATALVIGCVEGSTQLDQQMK--LKSMHQTKSKDMTFGNMLQPKRRISTDQTVFNIYKGIQTFDFGKSKNVLVTGGLDRIIRLWNPYVNSKPTGMLRGHNKPLVYVHIAEQENRIFSICADKCVKVWDLHDHNCLLTVRPKGHRIRGDMQSCHYSDFAKSLMIATDQVSMLNIKINPFVAEKQLDERHQRASYLGGCYFEQISQNTVLVNKPPVLHTDVAVTHKDPVTCCKYNEAFNQVVTCCEGSTVKLWNLSTGEKVFEFNEAHEDSGVTCLTFDSXXXXXXXXXXDGMVRMWNFNNGHCLTELKKEESDLKYAEISAVEYVEISRNKFIVSVGWDRAINVYIDQCEPGMHKSYYPQSRWLDDMSNGHKEDILTLATLKGHLLATADYHGTIIVWNLMSGHVFFKLISPVAXXXXXXXXXXXXXSINKLLFLQSRAKNKSSASLVASGPY---GLVHFWNVKEGGILYGRFKGGTESGQSLTAMIACKDQDIDDKLLFIGDRFGFISVWDIENYANNKVETDCPELLRRWRAHVSSITSLDLVLQSQVLITSSDDCTVRVWTFEGEYVGTFGQTEMWDLTNPKTFQHPMVPYDVLVHPQSLPDHPVLGPRMTIEQRKEQSKAESTHKAKMTKQHALQSENSTFTHKNVIYIDDEEINQQIEQKIYKEGKGKRLRFERMKPRNALSEDGGPNEYRSLQVFELAKTPS 3409
            RPSSA G IQT         +   +  +       P    +K+ G+ +   K S++ + P D + +       RR ++ + D    TK I ++ S+     +L   KIE+R+ L  L +LK AFE+ E   +  LDL  F+  ++  L L    D Q   LF KID++  G++ WDEFCTYMQLEY EKEE  ++++++AF LPA ++   H E +++I   SDG  +    DG +S+WS+TL+L+K KSV   E+    K+KW  D + M ++NK+I+ TGDREI+ +ELSS EP+C+I+SLE VPL LDY       D+C +++GD +GCV+I+ + + GE LR WKK P+ E +  I +++ + +P+I + RWKVH DWV K+KY+ S+  ++S SN EA+ALVIGC+  ST ++QQM+   ++  + K K   FG +  P++R++ DQTVF+IYKG++TFDF  ++N+L+TGG+DR+IR+WNPYV   PTG+L+GH+ P+ Y+HIA ++ R+FS+  D   ++WD+ D +CL    PK   +RG++ +C YS   + L I+TD +++L++K     AE Q            G Y                       +HK+ V CC Y+  F QVV+C EGS +K+W++ TG ++FEF  AH  S VTC+TFD  GRRL+TGGRDG +R+WNFNNGHCL  L +E+      EI    Y+++ RN F++SVGW R I+VY+D  E   H    P+  W DD+  GH+ED+L +A    +LLAT  Y G II+WNL+SG +  + ++P        D    D S+  L+FL++RA + + +S  +       G VHFWNV+ GG     F       Q     +       DD+LLF GD  G++ V+DI++ A   +  D P  +  WRAH+SSIT L L+   QVL+TSS DCTVR+W+  GE++GTFGQ E W L    +++HP VPY+VL+ P SLP H  L  +  I+   +   +EST           +S++       +    D E+ ++I    Y + +  R R E  K  N   +  GP  Y +L+ +++   P+
Sbjct:   42 RPSSAQGRIQTQ--------NVSSVLTETGPGPGAPGPVLIKQTGSELQE-KRSEKSVNP-DWLERALLKQEYRRHSLPLGDA---TKLITQQRSIRNPASSLSKLKIEQRVSLENLTKLKLAFEDYEKAGTRSLDLPRFRQTIRRCLGLRDITDAQIRELFMKIDYSGQGSVEWDEFCTYMQLEYTEKEELVVRSKQVAFALPATMKPLSHGEPILKIHQISDGMIVTLKEDGAVSYWSSTLQLRKSKSVFH-ERPIGRKAKWATDLVTMPQYNKLIIGTGDREIQLYELSSLEPHCQINSLETVPLKLDYCYT--GPDECAVVYGDAQGCVSIILMTSVGETLRLWKKLPKVENVPSISIDHAVQSPNITYIRWKVHEDWVTKVKYFQSIPAVVSTSNHEASALVIGCILPSTNIEQQMREIKEACREGKGKKAGFG-VSSPQQRVACDQTVFSIYKGVKTFDFCTTRNLLITGGMDRLIRMWNPYVPGSPTGILKGHSAPIFYLHIATEDGRVFSVSTDNSARIWDIQDQSCLFAAHPKASFLRGELTACLYSPAVRGLYISTDSLALLSLKTK---AEPQ------------GSY---------------------TTSHKEAVLCCGYSAGFRQVVSCSEGSVIKVWDVDTGNEMFEFGGAHGLSAVTCMTFDPKGRRLVTGGRDGCLRIWNFNNGHCLKTLSREDG---APEICDCCYLQVHRNTFVMSVGWARRIDVYLDSAEDTRHVQ-RPKPAWEDDLMKGHREDVLCVAQCPPYLLATGSYDGEIIMWNLVSGRIQSRFLTPPP--PNAEDPQTVDRSVLSLVFLRTRAIDAAFSSAASLLSSGAQGQVHFWNVQNGGKFVQSFNASRLQQQIRKLAVTA-----DDRLLFAGDDVGYVCVYDIQHCA-LALRQDPPPTVNFWRAHISSITGLHLIESEQVLLTSSTDCTVRLWSITGEFIGTFGQRERWSLHTASSWKHPAVPYEVLIDPLSLPSHCRLDGK--IQTLSDVLSSESTEDT--------ESDSPNKVRNRLPSSSDREM-EEINSAFYPQHRKWR-RHEIFKHANKSPDHAGPKLYHALKCYDVDDVPA 1073          

Query: 1451 VFNIYKGIQTFDFGKSKNVLVTGGLDRIIRLWNPYVNSKPTGMLRGHNKPLVYVHIAEQENRIFSICADKCVKVWDLHDHNCLLTVRPKGHRIRGDMQSCHYSDFAKSLMIATDQVSMLNIKINPFVAEKQLDERHQRASYLGGCYFEQISQNTVLVNKPPVLHTDVAVTHKDPVTCCKYNEAFNQVVTCCEGSTVKLWNLSTGEKVFEFNEAHEDSGVTCLTFDSXXXXXXXXXXDGMVRMWNFNNGHCLTELKKEESDLKYAEISAVEYVEISRNKFIVSVGWDRAINVYIDQCEPGMHKSYYPQS-RWLDDMSNGHKEDILTLATLKG-HLLATADYHGTIIVWNLMSGHVFFKLISPVAXXXXXXXXXXXXXSINKLLFLQSRAKNKS--SASLVASGPYGLVHFWNVKEGGILYGRFKGGTESGQSLTAMIACKDQDIDDKLLFIGDRFGFISVWDIENYA---NNKVETDCPELLRRWRAHVSSITSLDLVLQSQ--VLITSSDDCTVRVWTFEGEYVGTFGQTEMWDLTNPKTFQ 3049
            ++ I KGI  FD   S  +LVT GLD  +R+WN YV S+P  +L GH   +V V I +  ++IFS   D  +K+WD+    C+ T+  +   I+    +C     +  L+++      L I    +++  +L                   QN     +P               +C  Y     QVVT C  S+V +W+++TG K  E N AH    +T +T D + RRL+T   +G +++W+  NG  L +L+     +  AE++ V  +    +  +++VGW R +  Y      G H  Y      W       H EDIL      G  LLAT  Y G IIVW L +     +L  P+               I++LLFLQ R +++   + +L+ S   G + +W++      + +F       + + A+      + D+ LL  GD  G I VW+I  Y     ++V ++ P L+  WRAH  ++ S++++   +   L++ S D    +WT  G  VG+FGQ  +WDL +  T++
Sbjct:  319 IWKIEKGILCFDISWSLGLLVTAGLDPALRIWNRYVTSRPAAVLHGHRTTVVDVVIHQTLDKIFSYSKDAVLKMWDICSQQCVKTLSLRFPNIQ---PACFPEQGSFPLLLSLAAAPALLISCREYLSLLRL-------------------QNPTSNCRPSTF------------SCTLYIPKLKQVVTACAKSSVVVWDVNTGRKCMELNNAHGQEEITAMTADPSQRRLITAASNGTIKVWSLQNGRPLHKLEA----VSDAEVTGVICLH---DDQLLAVGWSRLVARY---SIGGSHDMYVKADVSW--KSGRLHSEDILAADHCAGKRLLATGSYDGEIIVWTLDTQRPVARLQRPLP--------GRVYPPIDRLLFLQKRVEDQQWRNRALLLSSQAGYICWWSICGPTHNHAKFYVPQREDERVNAL----RTNHDNSLLITGDTTGSIQVWNISQYGLYDGDEVVSEQPPLVHTWRAHEEAVVSMEVLEHGKDLFLVSVSVDLNACLWTSCGVCVGSFGQELLWDLNDLHTYR 802          

Query:  488 RSGKLDLSEFKALLKEKLQLPTFEDIQTETLFKKIDWASSGAINWDEFCTYMQLEYAEKEETYLKAREMAFCLPARIENTPH--RENVIRITSTSDGS---FIAGSTDGILSFW-SNTLE----LKKCKSVVTIEQSQRVKSKWIIDFLIMNEFNKIIVATGDREIEFFELSS 976
            ++G  DL + +  L  ++   ++     E L  ++D +  G   W++ CTY+  + A  E+     + +    P  I +  H  RE V RI   S      +I  S  G L+ W S++L+    L+ C        S R    WI D + M   +K+ VA+  R+I   ++SS
Sbjct:   65 KTGSSDLEQLRTALTAEVGEESWNS-SLEELVNELDLSCEGGDGWEKLCTYVLQKSAHNEDLSEPKQSIISSDPL-IRHCRHVKREPVTRIVEVSQPPPLRYITISKGGTLTVWNSSSLQAIRSLELCGGAGETGGSGRQFRGWITDAVYMPNIHKVAVASMSRDIHLIDVSS 235          

Query: 1997 AFNQVVTCCEGSTVKLWNLSTGEKVFEFNEAHEDSGVTCLTFDSXXXXXXXXXXDGMVRMWNFNNGHCLTELKKEESDLKYAEISAVEYVEISRNKFIVSVGWDRAINVYIDQCEPGMH-KSYYPQSRWLDDMSNGHKEDILTLATLKG-HLLATADYHGTIIVWNLMSGHVFFKLISPVAXXXXXXXXXXXXXSINKLLFLQSRAKNKS--SASLVASGPYGLVHFWNVKEGGILYGRFKGGTESGQSLTAMIACKDQDIDDKLLFIGDRFGFISVWDIENYANNKVETDCPELLRRWRAHVSSITSLDLVLQSQ--VLITSSDDCTVRVWTFEGEYVGTFGQTEMWDLTNPKTFQHPM 3058
            A   VVT C  S+V +W+++TG K  E N AH    +T +T D + RRL+T   +G +++W+  NG  L +L+     +  AE++ V  +    +  +++VGW R +  Y      G H +  Y ++         H EDIL      G  LLAT  Y G IIVW L +     +L  P+               I++LLFLQ R +++   + +L+ S   G + +W++      + +F       + + A+      + D+ LL  GD  G I VW+I  Y     +   P L+  WRAH  ++ S++++   +   L++ S D    +WT  G  VG+FGQ  +WDL +  T++ P+
Sbjct:  113 AAAPVVTACAKSSVVVWDVNTGRKCMELNNAHGQEEITAMTADPSQRRLITAASNGTIKVWSLQNGRPLHKLEA----VSDAEVTGVICLH---DDQLLAVGWSRLVARY---SIGGSHVRDMYVKADVSWKSGRLHSEDILAADHCAGKRLLATGSYDGEIIVWTLDTQRPVARLQRPLP--------GRVYPPIDRLLFLQKRVEDQQWRNRALLLSSQAGYICWWSICGPTHNHAKFYVPQREDERVNAL----RTNHDNSLLITGDTTGSIQVWNISQYGLYDGDEQ-PPLVHTWRAHEEAVVSMEVLEHGKDLFLVSVSVDLNACLWTSCGVCVGSFGQELLWDLNDLHTYRLPL 449          

Query:  578 LFKKIDWASSGAINWDEFCTYMQLEYAEKEETYLKAREMAFCLPARIENTPHRENVIRITSTSD-GSFIAGSTDGILSFWSNTLELKKCKSVVTIEQSQRVKSKWIIDFLIMNEFNKIIVATGDREIEFFELSS--FEPYCRIHSLENVPLCLDYYVDKDNLDDCLILWGDRKGCVNILHLHATGECLRT 1138
            LF  +D +  G +NW+   +Y  L  +EK+E ++K   +    PAR    PHR+ +  IT   + G ++  S DG L+ W     L   +S      + R K  W    +++    KI V+   +EI F++L S  F    ++H L   P+ L Y+   D  D  ++ +GD  G V       +G C R+
Sbjct:   61 LFDSVDVSREGWVNWERLTSYFLLGLSEKDE-HIKTTAVLRWRPARTLPVPHRDRLHSITHLPNAGRYLTLSKDGTLTVWEEK-NLTLLRSHRLTNDTVRPKDLWATGLVLLPNVQKIAVSFTSKEICFYDLMSKDFNLQYKLHGLHYTPISLHYWYHPDRPDQAVLSFGDAGGQV-------SGVCFRS 241          

Query: 1580 LRGHNKPLVYVHIAEQENRIFSICADKCVKVWDLHDHNCLLTVRPKGHRIRGDMQSCHYSDFAKSLMIATDQVSMLNIKINPFVAEKQLDERHQRASYLGGCYFEQISQNTVLVNKPPVLHTDVAVTHKDPVTCCKYNEAFNQVVTCCEGSTVKLWNLSTGEKVFEFNEAHEDSGVTCLTFDSXXXXXXXXXXDGMVRMWNFNNGHCLTELKKEESDLKYAEISAVEYVEISRN-KFIVSVGWDRAINVYIDQCEPGMHKSYYPQSRWLDDMSNGHKED----ILTLATLKGHLLATADYHGTIIVWNLMSGHVFFKL 2518
            L GH K +  V  +     + S  ADK +K+W  +D     T+   GH++   +    +S  +  L+ A+D  ++   KI    + K L      ++Y                                 V CC +N   N +V+     +V++W++ TG K  +   AH D  V+ + F+  G  +++   DG+ R+W+  +G CL  L  +++         V +V+ S N K+I++   D  + ++ D  +    K+Y            GHK +        +   G  + +      + +WNL +  +  KL
Sbjct:   41 LAGHTKAVSSVKFSPSGEWLASSSADKLIKIWGAYDGKFEKTIS--GHKL--GISDVAWSSDSNLLVSASDDKTL---KIWDVSSGKCLKTLKGHSNY---------------------------------VFCCNFNPQSNLIVSGSFDESVRIWDVKTG-KCLKTLPAHSDP-VSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDN-------PPVSFVKFSPNGKYILAATLDNTLKLW-DYSKGKCLKTY-----------TGHKNEKYCIFANFSVTGGKWIVSGSEDNMVYIWNLQTKEIVQKL 297          

Query: 1493 KSKNVLVTGGLDRIIRLWNPYVNSKPTGMLRGHNKPLVYVHIAEQENRIFSICADKCVKVWDLHDHNCLLTVRPKGHRIRGDMQSCHYSDFAKSLMIATDQ-VSMLNIKINPFVAEKQLDERHQRASYLGGCYFEQISQNTVLVNKPPVLHTDVAVTHKDPVTCCKYNEAFNQVVTCCEGSTVKLWNLSTGEKVFEFNEAHEDSGVTCLTFDSXXXXXXXXXXDGMVRMWNFNNGHCLTELKKEESDLKYAEISAVEYVEISRNKFIVSVGWDRAINVYIDQCEPGMHKSYYPQSRWLDDMSNGHKEDILTLATLKGHLLATADYHGTIIVWNLMSGHVFFKLISPVAXXXXXXXXXXXXXSINKLLFLQSRAKNKSSASL-VASGPYGLVHFWNVKEGGILYGRFKGGTESGQSLTAMIACKDQDIDDKLLFIGDRFGFISVWDIENYANNKVETDCPELLRRWRAHVSSITSLDLVLQSQVLITSSDDCTVRVWTFEGEYVGTFGQTEMWDLTNPKTFQHPMVPYDVLVHP 3085
            K ++++VTGG+DR +RLWNPYV  +PTG+LRGH  P+ Y+ I E+ +RIFS+ +D+ VKVWD  +  CL +V PK   +RG++ +CHY   A++L +AT+  V++L+++          D  H  A                            A +H++PV CC+Y+  F QVV+C E S VKLW+L +G   FEF  AH +S +TC+ FDS+GRRL+TGGRDG +++WN+NNG CL  L+K+ +     EI    YV +++NK+I+SVGWD+ IN+++D  E       +PQ  W DD+  GH+ED+L +A     LLAT+ Y G +IVWNL+SGHV  +L  P A    D    D+  S++K++FL+SR  +K  A+L VASGP G +HFWNV  GG L+ RF  G +        + C    + D +L   D+ G +  WD+ +YA    E + P+L+  WRAHVS+ITS+D++ + ++L+T++ DC+VR+W+ +G +VGTFGQ  +WD+ N  T+ HPM P ++LV P
Sbjct:    9 KERSLVVTGGMDRTVRLWNPYVPGRPTGVLRGHTSPICYLSICEETSRIFSVGSDRNVKVWDAQEQTCLCSVSPKMSGLRGEVSACHYLPAARALCVATEGGVALLSVR----------DGLHMDAG--------------------------AATSHREPVRCCRYSAEFRQVVSCSEDSVVKLWDLDSGLPTFEFCGAHGESAITCMAFDSSGRRLITGGRDGCLKVWNYNNGQCLRTLRKQRN---AEEICDCTYVVVNKNKYIISVGWDKRINIFLDSQE-DQQLIQFPQPHWADDLRKGHREDVLCVAQCPPSLLATSSYDGEVIVWNLVSGHVSCRLPPPPAQRSADPAEDDDL-SVSKVIFLKSRVAHKDRAALLVASGPRGFIHFWNVYHGGRLFARFPAGRQGRP-----VCCLASALGDSVLLAADQTGHVYAWDVSSYAMQGPEEEPPQLVSLWRAHVSAITSMDVIEEHKLLLTAALDCSVRLWSVDGAFVGTFGQDTLWDIHNRATWSHPMGPLEILVDP 495          

Query: 1469 GIQTFDFGKSKNVLVTGGLDRIIRLWN-------PYVNSKPTGMLRGHNKPLVYVHIAEQENRIFSICADKCVKVWDLHDHNCLLTVRPKGHRIRGDMQSCHYSDFAKSLMIATDQVSMLNIKINPFVAEKQLDERHQRASYLGGCYFEQISQNTVLVNKPPVLHTDVAVTHKDPVTCCKYNEAFNQVVTCCEGSTVKLWNLSTGEKVFEFNEAHEDSGVTCLTFDSXXXXXXXXXXDGMVRMWNFNNGHCLTELK 2215
            G+       S N L T G D I+R+WN       P++ S     +  H   +  V +      + S  +D  VKVW+ H   C+ T+R              + D+ K+L  A D+           VA   LD +          +   ++  T L      + T     +KD +     N+    +V+      +++W+  T  K+ +  + H D+ V  L  +  G + L+G  DG +R+W+     C+   +
Sbjct:   32 GVNALQLDHSLNRLFTAGRDSIVRIWNVSQHKQDPFIAS-----MEHHTDWVNDVVLCCNGRTLISASSDTTVKVWNAHKGFCMSTLRT-------------HKDYVKALAYAKDKEQ---------VASAGLDRQ---------IFLWDVNTLTALTASNNTVTTSSLSGNKDSIYSLAMNQMGTIIVSGSTEKVLRVWDPRTCAKLMKL-KGHTDN-VKALLLNRDGTQCLSGSSDGTIRLWSLGQQRCIATYR 249          

Query: 1469 GIQTFDFGKSKNVLVTGGLDRIIRLWN-------PYVNSKPTGMLRGHNKPLVYVHIAEQENRIFSICADKCVKVWDLHDHNCLLTVRPKGHRIRGDMQSCHYSDFAKSLMIATDQVSMLNIKINPFVAEKQLDERHQRASYLGGCYFEQISQNTVLVNKPPVLHTDVAVTHKDPVTCCKYNEAFNQVVTCCEGSTVKLWNLSTGEKVFEFNEAHEDSGVTCLTFDSXXXXXXXXXXDGMVRMWNFNNGHCLTELK 2215
            G+       S N L T G D I+R+WN       P++ S     +  H   +  V +      + S  +D  VKVW+ H   C+ T+R              + D+ K+L  A D+           VA   LD +          +   ++  T L      + T     +KD +     N+    +V+      +++W+  T  K+ +  + H D+ V  L  +  G + L+G  DG +R+W+     C+   +
Sbjct:   32 GVNALQLDHSLNRLFTAGRDSIVRIWNVSQHKQDPFIAS-----MEHHTDWVNDVVLCCNGRTLISASSDTTVKVWNAHKGFCMSTLRT-------------HKDYVKALAYAKDKEQ---------VASAGLDRQ---------IFLWDVNTLTALTASNNTVTTSSLSGNKDSIYSLAMNQMGTIIVSGSTEKVLRVWDPRTCAKLMKL-KGHTDN-VKALLLNRDGTQCLSGSSDGTIRLWSLGQQRCIATYR 249          

Query: 1835 EKQLDERHQRASYLGGCYFEQISQNTVLVNKPPVLHTDVAVTHKDPVTCCKYNEAFNQVVTCCEGSTVKLWNLSTGEKVFEFN-EAHEDSGVTCLTFDSXXXXXXXXXXDGMVRMWNFNNGHCLTELKKEESDLKYAEISAVEYVEISRNKFIVSVGWDRAINVYIDQCEPGMHKSYYPQSRWLDDMSNGHKEDI-LTLATLKGHLLATADYHGTIIVWNLMSGHVFFKLISPVAXXXXXXXXXXXXXSINKLLFLQSRAKNKSSASLVASGPYGL-------VHFWNVKEG--------------GILY---GRFKGGTESGQSLTAMIACKDQDIDDKLLFIGDRFGFISVWDIENYANNKVETDCPELLRRWRAHVSSITSLDLVLQSQVLITSSDDCTVRVW 2974
            E +L+E  +     GG    Q    +  + +PP  +      H+ PVT   ++  F+ +V+  E +T+K+W+  TG+  FE   + H DS V  ++FD +G+ L +   D  V++W+F +  CL  +   + +     +S+V +  +     +VS   D+ +            K +  Q+ +      GH+E + +      G L+A+     T+ VW   +     +L                  + + ++   + A+ K        GPY L       +  W++  G              G+L+   G+F            +++C     DDK L          VWD   Y N + +       +   AH   +TSLD    +  +IT S D +V+VW
Sbjct:    6 ESKLNEAKEEFVSGGGPLGGQRRDPSEWIPRPPEKY--ALSGHRSPVTRVIFHPVFSVIVSASEDATIKVWDYETGD--FERTLKGHTDS-VQDISFDLSGKMLASCSADMTVKLWDFQSFECLRTMHGHDHN-----VSSVAF--MPNGDHLVSASRDKTM------------KMWEVQTGYCVKTFTGHREWVRMVRPNQDGSLIASCSNDQTVRVWVTATKECKAELRE---HEHVVECVSWAPDAASPVILEATGAEAKKGGK---PGPYLLSGSRDKTIKMWDISTGICVITLVGHDNWVRGVLFHPGGKF------------ILSCA----DDKTL---------RVWD---YKNKRCQ-------KSLAAHEHFVTSLDFHKTAPYVITGSVDQSVKVW 346          

Query: 1961 HKDPVTCCKYNEAFNQVVTCCEGSTVKLWNLSTGEKVFEFNEAHEDSGVTCLTFDSXXXXXXXXXXDGMVRMWNFNNGHCL 2203
            H D VT   YN   N  V+C    T+KLW+  +   V  ++ AH  + V  + F    + +L+ G+D MVR+W  + G  L
Sbjct:  265 HTDAVTGVAYNPTANSYVSCSRDGTIKLWDGVSSRCVATYDRAHGGAPVCSVVFSRNAKYVLSSGKDSMVRLWELSAGRAL 345          

Query: 1469 GIQTFDFGKSKNVLVTGGLDRIIRLWNPYVNSKPTGMLRGHNKPLVYVHIAEQENRIFSICADKCVKVWDLHDHNCLLTVRPKGHRIRGDMQSCHYSDFAKSLMIATDQVSMLNIKINPF--VAEKQLDERHQRASYLGGCYFEQISQNTVLVNKP---PVLHTDVAVTHKDPV----TCCKYNEAF-NQVVTCCEGSTVKLWNLSTGEKVFEFNEAHEDSGVTCLTFDSXXXXXXXXXXDGMVRMWNFNNGHCL 2203
            G++T  F   K  L+TG LD+ IR+WN Y+  +     RGH+  ++ V     +  I S  ADK VKVW +    C  T+R  GH    +    H   F+         + M +I+ N    V    + +  +             + NT   + P   P + TD A     P     T    N  +   +++C   +T+KLW++ TG K       H + GV  +  D+   R+++G  DG +++W+  +G C+
Sbjct:  344 GVKTLYFDDRK--LITGSLDKTIRVWN-YITGECISTYRGHSDSVLSVD--SYQKVIVSGSADKTVKVWHVESRTC-YTLR--GHTEWVNCVKLHPKSFSCFSCSDDTTIRMWDIRTNSCLKVFRGHVGQVQKIIPLTIKDVENLATDNTSDGSSPQDDPTM-TDGADESDTPSNEQETVLDENIPYPTHLLSCGLDNTIKLWDVKTG-KCIRTQFGHVE-GVWDIAADN--FRIISGSHDGSIKVWDLQSGKCM 585          

Query: 1490 GKSKNVLVTGGLDRIIRLWNPYVNSKPTGMLRGHNKPLVYVHIAEQENRIFSICADKCVKVWDLHDHNCLLTVRPKGH 1723
            G S+ ++VT   D  + LWNP  ++KP   + GH K + +V  +     I S   D  +K+WD  D   + T R  GH
Sbjct:  368 GNSEEMMVTASDDYTMFLWNPLKSTKPIARMTGHQKLVNHVAFSPDGRYIVSASFDNSIKLWDGRDGKFISTFR--GH 443          

Query:  467 FENAEYDRSGKLDLSEFKALLKEKLQLPTFEDIQTETLFKKIDWASSGAINWDEFCTYMQLEYAEKEETYLKAREMAFCLPARIENTPHRENVIRITSTSDGSFIAGSTDGILSFWSNTLELKKCKSVVTIEQSQRVKSKWIIDFLIMNEFNKIIVATGDREIEFFELSSFEPYCRIHSLENVPLCLDYYVDKDNLDDCLILWGDRKGCVNILHLHATGECLRTWKKQPRSEGIAGIGMENVLSNPSIKFYRWKVHNDWVLKLKYYDSLRQIISCSNDEATALVIGCVEGSTQLDQQMKLKSMHQTKSKDMTFGNML--QPKRRISTDQTVFNIYKGIQTFDFGKSKNVLVTGGLDRIIRLWNPYVNSKPTGMLRGHNKPLVYVHIAEQENRIFSICADKCVKVWDLHDHNCLLTVRPKGHRIRGDMQSCHYSDFAKSLMIAT-DQVSMLNIKINPFVAEKQLDERHQRASYLGGCYFEQISQNTVLVNKPPVLHTDVAVTHKDPVTCCKYNEAFNQVVTCCEGSTVKLWNLSTGEKVFEFNEAHEDSGVTCLTFDSXXXXXXXXXXDGMVRMWNFNNGHCLTELKKEESDLKYAEISAVEYVEISRNKFIVSVGWDRAINVYIDQCEPGMHKSYYPQSRWLDDMSNGHKEDILTLATLKGHLLATADYHGTIIVWNLMSGHVFFKLISPVAXXXXXXXXXXXXXSINKLLFLQSRAKNKSSASLVASGPYGLVHFWNVKEGGILYGRFKGGTESGQSLTAMIACKDQDIDDKLLFIGDRFGFISVWDIENY 2833
             + A+ D SG LDL EFK +++         D Q   LF KID +S G INWDEFCT+MQLEYAEKEE+Y +++E +F LPA  EN+  RE VIR+  TSD +F+  S DG++SFWS  LE K+ K +    +S   K+KWI D+++M  FNK I++TGDREI+FFELS+FEPYC+I  LE  PL +DY     + D+C+I++GD +GCVNI  +H+TGE LR WKK P+ EGIA + +++V+++ + KF RWKVHNDWV +LKYYDSLR +ISCSN + TALVIG   GST ++ Q++  +  Q + K      +   QP+RR+ +DQTVF +YKG++TFDF K KN++VTGG+DR++R+WNPYV SKPTG+LRGH  P+ ++ I  +++RIFSI  DK VKVWDLHD +CLLTVRPK H+IRGD+ + HY+  ++ L +AT DQV++L +K  P                                        D+  THK+ VTC KYN++F  VVT  EGS  ++W++ TG  VFEFN+ H D+ +TC+ FDST RRL++GGRDG +R+WN+NNGHC+  L+KE+      E++ + Y+ + +N++I+SVGWDR INV+ D  +   H    P   W DD+ NGHKEDIL++A    +LLAT+ Y G II+WN +SGH+F  + SP+                           NK SA+LVASGP G VHFWNV  GG LY  F+    S       ++C   D D+K L   D  GF+ VWD+E+Y
Sbjct:    1 MQEADTDGSGTLDLDEFKDVIQALFGFKFKNDDQMTALFMKIDSSSDGEINWDEFCTFMQLEYAEKEESYFRSKETSFQLPALTENSSQREQVIRVCHTSDNNFLVVSQDGLVSFWSQNLEFKRMKHI----ESSSKKTKWITDYVLMPHFNKFIISTGDREIQFFELSTFEPYCQISGLETTPLRVDYC--SPSTDECIIIYGDSQGCVNIFIMHSTGETLRNWKKMPKVEGIASVNIDSVVNSENTKFIRWKVHNDWVAQLKYYDSLRAVISCSNHQETALVIGQTTGSTHIEAQLRENTTSQGERKKNVAAVVRDNQPRRRLDSDQTVFRVYKGVKTFDFCKEKNLIVTGGMDRLVRMWNPYVPSKPTGILRGHTAPIFHLFIVAEDDRIFSISTDKTVKVWDLHDQSCLLTVRPKAHKIRGDVSAIHYNPSSRGLAVATSDQVALLPLKTKPSAR-------------------------------------DMTTTHKEAVTCLKYNKSFKHVVTASEGSVCRVWDVETGHAVFEFNQLHGDTAITCMAFDSTERRLISGGRDGRLRIWNYNNGHCIRTLEKEKD---IDEVTDLTYIVMHKNRYIISVGWDRRINVFSDDTD-DFHHVQRPYIDWSDDLLNGHKEDILSVAVCPPNLLATSSYDGEIIIWNRVSGHIFCHIHSPL-------------------------PSNKESATLVASGPQGYVHFWNVYNGGQLYAAFRASQYS-------VSCMATDSDNKRLVTTDSAGFLYVWDVEDY 713          

Query:  416 KIEERIDLTVLEELKAAF--ENAEYDRSGKLDLSEFKALLKEKLQLPTFEDIQTETLFKKIDWASSGAINWDEFCTYMQLEYAEKEETYLKAREMAFCLPARIENTPHRENVIRITSTSDGS-FIAGSTDGILSFWSNTLELKKCKSVVTIEQSQRVKSK--WIIDFLIMNEFNKIIVATGDREIEFFELSS---FEPYCRIHSLENVPLCLDYYVDKDNLDDCLILWGDRKGCVNILHLHATGECLRTWKKQPRSEGIAGIGMENVLSNPSIKFYRWKVHNDWVLKLKYYDSLRQIISCSNDEATALVIGCVEGSTQLDQQMKLKSMHQTKSKDMTFGNMLQPKRRISTDQTVFNIYKGIQTFDFGKSKNVLVTGGLDRIIRLWNPYVNSKPTGMLRGHNKPLVYVHIAEQENRIFSICADKCVKVWDLHDHNCLLTVRPKGHRIRGDMQSCHYSDFAKSLMIATDQVSMLNIKINPFVAEKQLDERHQRASYLGGCYFEQISQNTVLVNKPPVLHTDVAVTHKDPVTCCKYNEAFNQVVTCCEGSTVKLWNLSTGEKVFEFNEAHEDSGVTCLTFDSXXXXXXXXXXDGMVRMWNFNNGHCLTELKKEESDLKYAEISAVEYVEISRNKFIVSVGWDRAINVYIDQCEPGMHKSYYPQSRWLDDMSNGHKEDILTLATLKGHLLATADYHGTIIVWNLMSGHVFFKLISPVAXXXXX-------XXXXXXXXSINKLLFLQSRAKNKSS--ASLVASGPYGLVHFWNVKEGGILYGRFKGGTESGQSLTAMIACKDQDIDDKLLFIGDRFGFISVWDIENYANNKVE---TDCPELLRRWRAHVSSITSLDLVLQSQ--VLITSSDDCTVRVWTFEGEYVGTFGQTEMWDL 3028
            K+  R+ +  L+ ++ AF    +   R   LD+ +F  +L   L     E+   E LF KID A  G ++WD+F ++M LEY EK++  +K  ++      R  ++PH+E + RI+   + S +++ S +GIL  WS  L +K+ ++V        VK +  W+ DF+ M    K+ +A   +EI  ++LSS   F    RI +L++ PLCLD Y + D  ++ ++ +GD  G VN L   A    L     QP        G + V+                     Y   L   ISCS     +LV+G +E         K KS  +T                     T F I +G+  FD+ +  N++ T G++  + LWNPYV SKP G+LRGH + +V VH  E   ++ S+  DK +++WD H   CL   R  G   +G  +                      + I  F      DE H   S L   + +Q+   T++V KP V   D  ++H+ PVT   YN  FNQVVT C GS + +W + TG+KV +F  AH ++ +T +T D+T  RL T   DG V++W+F NGHC + L     D   AEI                                                S  H++DIL++A      +A+A Y G I++WN+ S      L++                   D   ++ KL+FL SR    SS  A+LV+    G+V FWN ++   L   F     +G SLT  +     D  +  L  GD  G I VWDI  Y   + +   T  P LL++++ H   I  + L+ +++  +++T+S DC+  +W  EG  +G FGQ E W +
Sbjct:   40 KLVSRLTMHDLKAIQDAFTINQSGQQRELSLDVDQFCEILSIVLNKGVREEY--EELFNKIDVAKEGFVDWDKFSSHMLLEYYEKDDR-MKTTQVPQWRELRNISSPHKEVIRRISPLINPSRYLSVSKEGILCLWS--LGMKQLRTVQVQPDQDEVKQRDLWVTDFIPMQNLYKLAIALTSKEIAIYDLSSKSEFNCQFRIKNLDDTPLCLD-YCNPDKPNEAILAFGDVSGQVNALLFSAVNIALFDRPAQP-------AGSKQVM---------------------YSAHLDCFISCSTSYKGSLVLGWIE---------KTKSNMRT---------------------TAFKIPQGVNAFDYNEKANLVATAGVNHHVCLWNPYVISKPVGVLRGHMQSVVAVHFIESRGQLISLSKDKVLRIWDTHLQVCLQ--RLSGMFPKGPAE----------------------VSITMF-----YDEEH---SKLFTAFNQQL---TLMVMKPEV--KDRVMSHEQPVTAAIYNSKFNQVVTACAGSVITMWMIDTGQKVKQFANAHGNAEITTITQDATETRLFTASADGTVKIWDF-NGHCHSILMAGNGD--PAEI------------------------------------------------SQEHQDDILSVAYSPPTTIASASYDGEIVIWNMNSEQASRHLVAEKRRKPPRSSRRNRLRADSDIGSAVTKLIFLNSRPLPTSSPGANLVSCCGSGIVRFWNSQKHAFL-AEFLAHQHAG-SLTMAV-----DGTNSYLVTGDADGLIKVWDISEYCVEEPDNTITQPPPLLKQFQPHTDIINHIGLLTRNERLLVLTASSDCSAALWDIEGRQIGVFGQEEHWKI 773          

Query:  776 FIAGSTDGILSFWSNTLELKKCKSVVTIEQSQRVKSKWIIDFLIMNEFNKIIVATGDREIEFFELSSFEPYCRIHS---LENVPLCLDYYVDKDN-LDDCLILWGDRKGCVNILHLHATGECLRTWKKQPRSEGIAGIGME-NVLSNPSIKFYRWKVHNDWVLKLKYYDSLRQIISCSNDEATALVIGCVEGSTQLDQQMKLKSMHQTKSKDMTFGNMLQPKRRISTDQTVFNIYKGIQTFDFGKSKNVLVTGGLDRIIRLWNPYVNSKPTGMLRGHNKPLVYVHIAEQENRIFSICADKCVKVWDLHDHNCLLTV-----RPKGHRIRGDMQSCHYSDFAKSLMIATDQVSMLNIKINPFVAEKQLDERHQRASYLGGCYFEQISQNTVLVNKPPVLHTDVAVTHKDPVTCCKYNEAFNQVVTCCEGSTVKLWNLSTGEKVFEFNEAHEDSG-VTCLTFDSXXXXXXXXXXDGMVRMWNFNNGHCLTELKKEESDLKYAE-ISAVEYVEISRNKFIVSVGWDRAINVYID 2332
            +I  S  GI+  WSN                   +S W+     +    +I  AT +R I  ++  +      I+    +EN P C+     K N +++  IL+GD +G VNIL + +    ++    +  S   A + +E N LS+   +  R K  +DWVLK+KY+  L     CS   + + ++G V                     D    N   P R +        + KG+  FD+    NV+VT G D+I+R+W+P + ++PTG L GH   +V + + E++ ++ S+   +  +VWDL    CL        RP   RI              S M+                     D +H R   + GC        T  +         V  TH  P++   YN   NQV++ C    +K+W + TG+ V++  +AH  S  VT +  D+TG RL+TG  DG ++ W+F +G    +   E +  +    I+ + Y  +   + ++   W + I +  D
Sbjct:  150 YITASQKGIICQWSNK------------------ESSWVTGCGFLPSLRRI-AATSERAIALWDYRAKRKQSTIYQIKPMENSPQCMTCIPWKANSMNEDTILFGDDQGYVNILTISSKDLHMKNSSAKGDS---AVVTIEPNKLSS---EIKRRKFFDDWVLKIKYFPQLEMFGCCSPGSSCSFILGGV---------------------DRVLNN--GPVREL-------GVPKGVNCFDYCTRANVIVTAGADKIVRIWHPLIFTRPTGKLLGHLFTIVEIAVNEKDQQLISLSTARVFRVWDLQTLTCLQVFTDNEERPGEKRI--------------SAML--------------------FDAKHDR--LITGCSVIDTWPLTRAIQD----SLQVPHTHDRPISQLLYNPQMNQVISVCTEGVMKVWEMETGQMVYQVTDAHGTSNEVTAMNVDNTGYRLITGAYDGSIKAWDFGSGQLYKKYPDEPAKKRQENTITGLVYHTVDNKRCVLVSSWGQGITLLED 585          

Query: 2618 SSASLVASGPYGLVHFWNVKEGGILYGRFKGGTESGQSLTAMIACKDQDIDDKLLFIGDRFGFISVWDIENYANNKVETDCPELLRRWRAHVSSITSLDLVLQSQVLITSSDDCTVRVWTFE-GEYVGTFGQTEMWDLTNPKTFQH-PMVPYDVLVHP 3085
            S  +LV++   G + FW +   G L    +  T    S    + C D D   + +  GD  G+++VWD     N   +  C      WRAH++ +  ++ V  +  ++T+S D +VRVW  + G ++G FGQ  +W L + K+    P+ PYD+   P
Sbjct:  783 SDPALVSAHHDGYLRFWTLS--GRLLTEIRAVTRRQASAVTSL-CTDADC--RHVISGDAKGYVTVWD-----NVIKQVVC------WRAHLTRVVGVEHVDSADAVVTASTDLSVRVWYRDTGHFIGFFGQPRLWHLPSAKSVPSTPVRPYDITESP 924          

Query:  398 KHNLLDKIEERIDLTVLEELKAAFENAEYDRSGKLDLSEFK-ALLKEKLQLPTFEDIQTETLFKKIDWASSGAINWDEFCTYMQLEYAEKEETYLKAREMAFCLPARIENTPHRENVIRIT-------------STSDGSFIAGSTDGILSFWSNTLELKKCKSVVTIEQSQRVKSKWIIDFLIMNEFNKIIVATGDREIEFFELS--SFEPYCRIHSLENVPLCLDYYVDKDNLDDCLILWGDRKGCVNILHLHAT 1120
            KH+ + ++E++++   LE L+  FE A+ D  G LD  EF+ A++K        +D Q    F K+D    G ++W+EFC+YM LE   K+      REM F  PAR   + HR+N+ RIT               + G ++  S +G+L FWS  L   +  +V    + +  KS WI D +++    KI V++ DREI F++ S  S E    +  LEN  LC+DY+ D  + +  ++L+GD  G V+ +   A 
Sbjct:   45 KHHAI-RLEDQMNNEHLEVLQRIFEEADEDGGGGLDYEEFRRAMIKTMSCKEVPDDNQLAITFMKVDANCDGTVDWEEFCSYMLLENQLKDVMTSDEREMEFPHPAREIPSAHRDNIARITYFAKMSHGPDESGDNNVGRYVTVSREGVLHFWSMDLNPIRTITVSNASEGKASKSVWITDCVVLPNAKKIAVSSADREIAFYDCSANSVEKQFVLSGLENCALCMDYWYDPRHPNQSILLFGDSGGKVSCIKFSAV 300          

Query: 2402 HKEDILTLATLKGHLLATADYHGTIIVWNLMSGHVFFKLISPVAXXXXXXXXXXXXXSINKLLFLQSRA--KNKSSASLVASGPYGLVHFWNVKEGGILYGRFKGGTESGQSLTAMIACKDQDIDDKLLFIGDRFGFISVWDIENYANNKVET----DCPELLRRWRAHVSSITSLDLVLQSQ--VLITSSDDCTVRVWTFEGEYVGTFGQTEMWDLTNPK 3040
            H++DIL  A    +LLAT  + G II+   +   +F +            +     L ++ LLFL SRA  K + SA LV+S   G + FW +       G F   +E   S+ A+      D  + +L  GD  G ISVWDI +Y  ++ E+      P  +  W AH  ++ SL++V + +   L++SS DCT R+WT +G+YVG FGQ    D+ + +
Sbjct:   13 HQDDILASAYCSPNLLATGSFDGDIILILKLIKLLFCR----------RKETKGGCLPVDTLLFLSSRAQWKTQDSAILVSS-ESGSLEFWCLYGAARPMGMFYAASEDSASVLALA----TDPSNDILVSGDSAGRISVWDITSYCISRAESIIAQGSPPCVITWHAHGGAVVSLEVVSRDEKLFLVSSSVDCTARLWTLDGKYVGMFGQVRHVDVISGR 218          

Query: 1460 IYKGIQTFDFGKSKNVLVTGGLDRIIRLWNPYVNSKPTGMLRGHNKPLVYVHIAEQENRIFSICADKCVKVWDLHDHNCLLTVRPKGHRIRGDMQSCHYSDFAKSLMIATDQVSMLNIKINPFVAEKQLDERHQRASYLGGCYFEQISQNTVLVNKPPVLHTDVAVTHKDPVTCCKYNEAFNQVVTCCEGSTVKLWNLSTGEKVFEFNEAHEDSGVTCLTFDSXXXXXXXXXXDGMVRMWNFNNGHCLTELKKEESDLKYAEISAVEYVEISRNKFIVSVGWDRAINVYIDQCEPGMHKSYYPQSRWLDDMSNGHKEDILTLATLKGHLLATADYHGTIIVWNLMSGHVFFKLISPV 2530
            ++  + T     +  +LVTGG+DR+IRLW+P+   KPTG+L+GH+ P+ ++ I+ ++++I S+  D  VK     D  CL T   K   I G++ +CHYS   KSL IA D +++L +K   F   ++L E                                   +H +PV CC Y+E F QVV+C EGS +K+W+L TG +      +   + +TC+T D  GRRL+TG RDG +++WNFN+G CL  LKK  ++             ++ N            N+Y            Y  + ++    NGHK+DIL +A     LLAT+   G IIVWN +SG +  + + PV
Sbjct:    8 LWSPVGTVSRVMNPKMLVTGGMDRLIRLWHPHFPGKPTGILKGHSAPIFFLWISSEDSQIVSVSVDCTVK-----DECCLFTGESKASSIYGEISACHYSPAMKSLYIAADSIAVLKLKPRSFFPRRRLTE-----------------------------------SHNEPVLCCCYSEEFRQVVSCGEGSVLKVWDLDTGRQGPVSERSSHGATITCMTMDDKGRRLITGRRDGSLKIWNFNSGQCLKTLKKGHAN------HCTTMQTMNSN------------NLY----------KRYKATTFVSFQINGHKDDILCVAHCPPSLLATSSCDGEIIVWNAVSGCILCRFVGPV 296          

Query: 2903 TSLDLVLQSQVLITSSDDCTVRVWTFEGEYVGTFGQTEMWDLTNPKTFQHPMVPYDVLVHPQSLPDHPVLG-----PRMTIEQRKEQSKAE 3160
            +SL +V   QV++TSS D TVR+W+  GE +GTFGQ E+W++    ++ HP  PY+VL+ P S+P+H  L      P+     + E  + E
Sbjct:  323 SSLQIVDSDQVVLTSSTDHTVRLWSAYGECIGTFGQPEIWNIHVSSSWMHPTDPYEVLIDPLSMPNHGTLNGKPRQPKPITRDKTEPDRGE 413          

Query:  608 GAINWDEFCTYMQLEYAEKEETYLKAREMAFCLPARIENTPHRENVIRITS-TSDGSFIAGSTDGILSFWS--NTLELKKCKSVVTIEQSQRVKSK--WIIDFLIMNEFNKIIVATGDREIEFFELSS---FEPYCRIHSLENVPLCLDYYVDKDNLDDCLILWGDRKGCVNILHLHAT------GECLRTWKKQPRSEGIAGIGMENVLS--NPSIKFYRWKVHND-WVLKLKYYDSLRQIISCSNDEATALVIGCVEGSTQLDQQMKLKSMHQTKSKDMTFGNMLQPKRRISTDQTVFNIYKGIQTFDFGKSKNVLVTGGLDRIIRLWNPYVNSKPTGMLRGHNKPLVYVHIAEQENRIFSICADKCVKVWDLHDHNCLLTV 1708
            G ++W   C+++ LE   ++    K   +    P R    PHR++V ++    S   ++  S  G +  W   +   L  C+      Q+  V S+  W+ D +++    KI V+    E+ F++L S   F    ++  L   P CLDY++D  + D  ++  GD  G V+ LH  +         CL     Q  S+    +  + ++   +   +    K H   WV K+ Y  SLR   SCS    +++VIG                      +D   G M     RI    T +   KG+   D+ +  N++ T GLD  + LWNPYV S+P   L GH   +  V   + ++++ S   DK + +WD+    C+  V
Sbjct:   84 GHVDWGALCSFL-LEETWRKLNQTKDFNVPLWKPRRTLTCPHRDSVQKVLYLQSSDQYLTVSKGGKVVLWQEVDLSVLSTCRL-----QNSTVASRDLWVTDVVLLQNVQKIAVSFTCEEVCFYDLRSKQDFPCKYKLQGLRFAPWCLDYWMDPCDADQAVLTIGDTGGQVSALHFTSAQTSLFESRCL-----QLDSDSAKVVSWDQLVKGRHSCCRMETHKAHAPAWVRKVLYLSSLRAFASCSTRPQSSMVIGW---------------------RDEGAGKM-----RI----TSYVTRKGVWDIDYHRQWNLIATAGLDDQVLLWNPYVTSEPVCALAGHLNEVTAVRFMQTKDQLLSFSKDKVLCLWDVSSQLCVQRV 426          

Query:  608 GAINWDEFCTYMQLEYAEKEETYLKAREMAFCLPARIENTPHRENVIRITS-TSDGSFIAGSTDGILSFWS--NTLELKKCKSVVTIEQSQRVKSK--WIIDFLIMNEFNKIIVATGDREIEFFELSS---FEPYCRIHSLENVPLCLDYYVDKDNLDDCLILWGDRKGCVNILHLHAT------GECLRTWKKQPRSEGIAGIGMENVLS--NPSIKFYRWKVHND-WVLKLKYYDSLRQIISCSNDEATALVIGCVEGSTQLDQQMKLKSMHQTKSKDMTFGNMLQPKRRISTDQTVFNIYKGIQTFDFGKSKNVLVTGGLDRIIRLWNPYVNSKPTGMLRGHNKPLVYVHIAEQENRIFSICADKCVKVWDLHDHNCLLTV 1708
            G ++W   C+++ LE   ++    K   +    P R    PHR++V ++    S   ++  S  G +  W   +   L  C+      Q+  V S+  W+ D +++    KI V+    E+ F++L S   F    ++  L   P CLDY++D  + D  ++  GD  G V+ LH  +         CL     Q  S+    +  + ++   +   +    K H   WV K+ Y  SLR   SCS    +++VIG                      +D   G M     RI    T +   KG+   D+ +  N++ T GLD  + LWNPYV S+P   L GH   +  V   + ++++ S   DK + +WD+    C+  V
Sbjct:   84 GHVDWGALCSFL-LEETWRKLNQTKDFNVPLWKPRRTLTCPHRDSVQKVLYLQSSDQYLTVSKGGKVVLWQEVDLSVLSTCRL-----QNSTVASRDLWVTDVVLLQNVQKIAVSFTCEEVCFYDLRSKQDFPCKYKLQGLRFAPWCLDYWMDPCDADQAVLTIGDTGGQVSALHFTSAQTSLFESRCL-----QLDSDSAKVVSWDQLVKGRHSCCRMETHKAHAPAWVRKVLYLSSLRAFASCSTRPQSSMVIGW---------------------RDEGAGKM-----RI----TSYVTRKGVWDIDYHRQWNLIATAGLDDQVLLWNPYVTSEPVCALAGHLNEVTAVRFMQTKDQLLSFSKDKVLCLWDVSSQLCVQRV 426          

Query:  608 GAINWDEFCTYMQLEYAEKEETYLKAREMAFCLPARIENTPHRENVIRITS-TSDGSFIAGSTDGILSFWS--NTLELKKCKSVVTIEQSQRVKSK--WIIDFLIMNEFNKIIVATGDREIEFFELSS---FEPYCRIHSLENVPLCLDYYVDKDNLDDCLILWGDRKGCVNILHLHAT------GECLRTWKKQPRSEGIAGIGMENVLS--NPSIKFYRWKVHND-WVLKLKYYDSLRQIISCSNDEATALVIGCVEGSTQLDQQMKLKSMHQTKSKDMTFGNMLQPKRRISTDQTVFNIYKGIQTFDFGKSKNVLVTGGLDRIIRLWNPYVNSKPTGMLRGHNKPLVYVHIAEQENRIFSICADKCVKVWDLHDHNCLLTV 1708
            G ++W   C+++ LE   ++    K   +    P R    PHR++V ++    S   ++  S  G +  W   +   L  C+      Q+  V S+  W+ D +++    KI V+    E+ F++L S   F    ++  L   P CLDY++D  + D  ++  GD  G V+ LH  +         CL     Q  S+    +  + ++   +   +    K H   WV K+ Y  SLR   SCS    +++VIG                      +D   G M     RI    T +   KG+   D+ +  N++ T GLD  + LWNPYV S+P   L GH   +  V   + ++++ S   DK + +WD+    C+  V
Sbjct:   84 GHVDWGALCSFL-LEETWRKLNQTKDFNVPLWKPRRTLTCPHRDSVQKVLYLQSSDQYLTVSKGGKVVLWQEVDLSVLSTCRL-----QNSTVASRDLWVTDVVLLQNVQKIAVSFTCEEVCFYDLRSKQDFPCKYKLQGLRFAPWCLDYWMDPCDADQAVLTIGDTGGQVSALHFTSAQTSLFESRCL-----QLDSDSAKVVSWDQLVKGRHSCCRMETHKAHAPAWVRKVLYLSSLRAFASCSTRPQSSMVIGW---------------------RDEGAGKM-----RI----TSYVTRKGVWDIDYHRQWNLIATAGLDDQVLLWNPYVTSEPVCALAGHLNEVTAVRFMQTKDQLLSFSKDKVLCLWDVSSQLCVQRV 426          

Query:  485 DRSGKLDLSEFKALLKEKLQLPTFEDIQTETLFKKIDWASSGAINWDEFCTYMQLEYAEKEETYLKAREMAFCLPA-RIENTPHRENVIRITSTSDGS---FIAGSTDGILSFWSNTLELKKCKSVVT-IEQSQRVKSKWIIDFLIMNEFNKIIVATGDREIEFFELSSFEPYCRIHSLEN----VPLCLDYYVDKDNLDDCLILWGDRKGCVNILHLHATGECLRTWKKQPRSE-GIAGIGMENVLSNPSIKFYR--WKVHNDWVLKLKYYDSLRQIISCSNDEATALVIGCVEGSTQLDQQMKLKSMHQTKSKDMTFGNMLQPKRRISTDQTVFNIYKGIQTFDFGKSKNVLVTGGLDRIIRLWNPYVNSKPTGMLRGHNKPLVYVHIAEQENRIFSICAD 1657
            D+   + L EFK  L     +   E+   E LF +ID + +G + W + C+Y+  EY E++        +    P   + +   RE  +RI S S      +I  S  G ++ WS++L + +   V    E S R++  W+ D   M   +++ + T  R+  F ++S  + +  +H          +C  +   +      L+L GD KG V+++    T + L  +K+  ++E G   I   ++  + ++   R    +H   + ++ +      I++ S  E T++V             MK+ SM Q                    +  ++   +G   FD+  S  +LVTGG DR IRLW+ YV   P  +L+GH   ++ V I +   +IFS   D
Sbjct:   68 DKQPGIKLEEFKKSLSS---VTCSEESWIEELFCEIDISHAGEVTWQQLCSYLLQEYKERQRASTPPAALLDAQPQFTLCSQNKREPTVRILSISQQPPLRYITVSKGGHITVWSSSLRILQTFMVSGDPEHSSRLRG-WVTDAAYMRGLHRVAIVTDHRDAHFVKVSPTDIFEDVHLFGFRCVLTAVCFGFDSQRPEQPPLLLL-GDEKGGVHLMWFLNTSKGL--FKRASKTERGPQRILFSDLDDHDNMVSCRHIANIHRAAINRVMFDPGANVIMTSSESETTSVVF------------MKV-SMKQ--------------------EPYIWKFSQGALCFDYSSSLQLLVTGGKDRKIRLWSRYVTFSPLAVLQGHQASVMDVAIYQPVEQIFSYSRD 430          

Query:   59 MSSVRVPIGGPVIKPSKIKIRPSSASGNIQTHQSYTTGLYDKKCLFLKDKIKESLPDSNKLKKAGTHIGFLKESQRIIEPKDEIRKPRRRTIEIVDGMDITKFIGREMSLSLRKHNLLDKIEERIDLTVLEELKAAFENAEYDRSGKLDLSEFKALLKEKLQLPTFEDIQTETLFKKIDWASSGAINWDEFCTYMQLEYAEKEETYLKAREMAFCLPARIENTPHRENVIRITSTSDGSFIAGSTDGILSFWSNTLELKKCKSVVTIEQSQRVKSKWIIDFLIMNEFNKIIVATGDREIEFFELSSFEPYCRIHSLENVPLCLDYYVDKDNLDDCLILWGDRKGCVNILHLHATGECLRTWKKQPRSEGIAGIGMENVLSNPSIKFYRWKVHNDWVLKLKYYDSLRQIISCSNDEATALVIGCVEGSTQLDQQMKLKSMHQTKSKDMTFGNMLQPKRRISTDQTVFNIYKGIQTFDFGKSKNVLVTGGLDRIIRLWNPYVNSKPTGMLRGHNKPLVYVHIAEQENRIFSICADKCVKVWDLHDHNCLLTVRPKGHRIRGDMQSCHYSDFAKSLMIATDQVSMLNIKINPFVAEKQLDERHQRASYLGGCYFEQISQNTVLVNKPPVLHTDVAVTHKDPVTCCKYNEAFNQVVTCCEGSTVKLWNLSTGEKVFEFNEAHEDSGVTCLTFDSXXXXXXXXXXDGMVRMWNFNNGHCLTELKKEESDLKYAEISAVEYVEISRNKFIVSVGWDRAINVYIDQCEPGMHKSYYPQSRWLDDMSNGHKEDILTLATLKGHLLATADYHGTIIVWNLMSGHVFFKLISPVAXXXXXXXXXXXXXSINKLLFLQSRAKNKSSASLVASGPYGLVHFWNVKEGGILYGRFKGGTESGQSLTAMIACKDQDIDDKLLFIGDRFGFISVWDIENYANNKVETDCPELLRRWRAHVSSITSLDLVLQSQVLITSSDDCTVRVWTFEGEYVGTFGQTEMWDLTNPKTFQHPMVPYDVLVHPQSLPDHPVLGPRMTIEQRKEQSKAESTHKAKMTKQHALQSENSTFTHKNVIYIDDEEINQQIEQKIYKEGKGKRLRFERMKPRNALSEDGGPNEYRSLQVFELAKTPSPRQPEILNQKK 3442
            MSSVRVPIGGPVIKPSKIKIRPSSASGNIQTHQSYTTGLYDKKCLFLKDKIKESLPDSNKLKKAGTHIGFLKESQRIIEPKDEIRKPRRRTIEIVDGMDITKFIGREMSLSLRKHNLLDKIEERIDLTVLEELKAAFENAEYDRSGKLDLSEFKALLKEKLQLPTFEDIQTETLFKKIDWASSGAINWDEFCTYMQLEYAEKEETYLKAREMAFCLPARIENTPHRENVIRITSTSDGSFIAGSTDGILSFWSNTLELKKCKSVVTIEQSQRVKSKWIIDFLIMNEFNKIIVATGDREIEFFELSSFEPYCRIHSLENVPLCLDYYVDKDNLDDCLILWGDRKGCVNILHLHATGECLRTWKKQPRSEGIAGIGMENVLSNPSIKFYRWKVHNDWVLKLKYYDSLRQIISCSNDEATALVIGCVEGSTQLDQQMKLKSMHQTKSKDMTFGNMLQPKRRISTDQTVFNIYKGIQTFDFGKSKNVLVTGGLDRIIRLWNPYVNSKPTGMLRGHNKPLVYVHIAEQENRIFSICADKCVKVWDLHDHNCLLTVRPKGHRIRGDMQSCHYSDFAKSLMIATDQVSMLNIKINPFVAEKQLDERHQRASYLGGCYFEQISQNTVLVNKPPVLHTDVAVTHKDPVTCCKYNEAFNQVVTCCEGSTVKLWNLSTGEKVFEFNEAHEDSGVTCLTFDSTGRRLLTGGRDGMVRMWNFNNGHCLTELKKEESDLKYAEISAVEYVEISRNKFIVSVGWDRAINVYIDQCEPGMHKSYYPQSRWLDDMSNGHKEDILTLATLKGHLLATADYHGTIIVWNLMSGHVFFKLISPVADLDEDTDYIDEDLSINKLLFLQSRAKNKSSASLVASGPYGLVHFWNVKEGGILYGRFKGGTESGQSLTAMIACKDQDIDDKLLFIGDRFGFISVWDIENYANNKVETDCPELLRRWRAHVSSITSLDLVLQSQVLITSSDDCTVRVWTFEGEYVGTFGQTEMWDLTNPKTFQHPMVPYDVLVHPQSLPDHPVLGPRMTIEQRKEQSKAESTHKAKMTKQHALQSENSTFTHKNVIYIDDEEINQQIEQKIYKEGKGKRLRFERMKPRNALSEDGGPNEYRSLQVFELAKTPSPRQPEILNQKK
Sbjct:    1 MSSVRVPIGGPVIKPSKIKIRPSSASGNIQTHQSYTTGLYDKKCLFLKDKIKESLPDSNKLKKAGTHIGFLKESQRIIEPKDEIRKPRRRTIEIVDGMDITKFIGREMSLSLRKHNLLDKIEERIDLTVLEELKAAFENAEYDRSGKLDLSEFKALLKEKLQLPTFEDIQTETLFKKIDWASSGAINWDEFCTYMQLEYAEKEETYLKAREMAFCLPARIENTPHRENVIRITSTSDGSFIAGSTDGILSFWSNTLELKKCKSVVTIEQSQRVKSKWIIDFLIMNEFNKIIVATGDREIEFFELSSFEPYCRIHSLENVPLCLDYYVDKDNLDDCLILWGDRKGCVNILHLHATGECLRTWKKQPRSEGIAGIGMENVLSNPSIKFYRWKVHNDWVLKLKYYDSLRQIISCSNDEATALVIGCVEGSTQLDQQMKLKSMHQTKSKDMTFGNMLQPKRRISTDQTVFNIYKGIQTFDFGKSKNVLVTGGLDRIIRLWNPYVNSKPTGMLRGHNKPLVYVHIAEQENRIFSICADKCVKVWDLHDHNCLLTVRPKGHRIRGDMQSCHYSDFAKSLMIATDQVSMLNIKINPFVAEKQLDERHQRASYLGGCYFEQISQNTVLVNKPPVLHTDVAVTHKDPVTCCKYNEAFNQVVTCCEGSTVKLWNLSTGEKVFEFNEAHEDSGVTCLTFDSTGRRLLTGGRDGMVRMWNFNNGHCLTELKKEESDLKYAEISAVEYVEISRNKFIVSVGWDRAINVYIDQCEPGMHKSYYPQSRWLDDMSNGHKEDILTLATLKGHLLATADYHGTIIVWNLMSGHVFFKLISPVADLDEDTDYIDEDLSINKLLFLQSRAKNKSSASLVASGPYGLVHFWNVKEGGILYGRFKGGTESGQSLTAMIACKDQDIDDKLLFIGDRFGFISVWDIENYANNKVETDCPELLRRWRAHVSSITSLDLVLQSQVLITSSDDCTVRVWTFEGEYVGTFGQTEMWDLTNPKTFQHPMVPYDVLVHPQSLPDHPVLGPRMTIEQRKEQSKAESTHKAKMTKQHALQSENSTFTHKNVIYIDDEEINQQIEQKIYKEGKGKRLRFERMKPRNALSEDGGPNEYRSLQVFELAKTPSPRQPEILNQKK 1128          

Query:   59 MSSVRVPIGGPVIKPSKIKIRPSSASGNIQTHQSYTTGLYDKKCLFLKDKIKESLPDSNKLKKAGTHIGFLKESQRIIEPKDEIRKPRRRTIEIVDGMDITKFIGREMSLSLRKHNLLDKIEERIDLTVLEELKAAFENAEYDRSGKLDLSEFKALLKEKLQLPTFEDIQTETLFKKIDWASSGAINWDEFCTYMQLEYAEKEETYLKAREMAFCLPARIENTPHRENVIRITSTSDGSFIAGSTDGILSFWSNTLELKKCKSVVTIEQSQRVKSKWIIDFLIMNEFNKIIVATGDREIEFFELSSFEPYCRIHSLENVPLCLDYYVDKDNLDDCLILWGDRKGCVNILHLHATGECLRTWKKQPRSEGIAGIGMENVLSNPSIKFYRWKVHNDWVLKLKYYDSLRQIISCSNDEATALVIGCVEGSTQLDQQMKLKSMHQTKSKDMTFGNMLQPKRRISTDQTVFNIYKGIQTFDFGKSKNVLVTGGLDRIIRLWNPYVNSKPTGMLRGHNKPLVYVHIAEQENRIFSICADKCVKVWDLHDHNCLLTVRPKGHRIRGDMQSCHYSDFAKSLMIATDQVSMLNIKINPFVAEKQLDERHQRASYLGGCYFEQISQNTVLVNKPPVLHTDVAVTHKDPVTCCKYNEAFNQVVTCCEGSTVKLWNLSTGEKVFEFNEAHEDSGVTCLTFDSXXXXXXXXXXDGMVRMWNFNNGHCLTELKKEESDLKYAEISAVEYVEISRNKFIVSVGWDRAINVYIDQCEPGMHKSYYPQSRWLDDMSNGHKEDILTLATLKGHLLATADYHGTIIVWNLMSGHVFFKLISPVAXXXXXXXXXXXXXSINKLLFLQSRAKNKSSASLVASGPYGLVHFWNVKEGGILYGRFKGGTESGQSLTAMIACKDQDIDDKLLFIGDRFGFISVWDIENYANNKVETDCPELLRRWRAHVSSITSLDLVLQSQVLITSSDDCTVRVWTFEGEYVGTFGQTEMWDLTNPKTFQHPMVPYDVLVHPQSLPDHPVLGPRMTIEQRKEQSKAESTHKAKMTKQHALQSENSTFTHKNVIYIDDEEINQQIEQKIYKEGKGKRLRFERMKPRNALSEDGGPNEYRSLQVFELAKTPSPRQPEILNQKK 3442
            MSSVRVPIGGPVIKPSKIKIRPSSASGNIQTHQSYTTGLYDKKCLFLKDKIKESLPDSNKLKKAGTHIGFLKESQRIIEPKDEIRKPRRRTIEIVDGMDITKFIGREMSLSLRKHNLLDKIEERIDLTVLEELKAAFENAEYDRSGKLDLSEFKALLKEKLQLPTFEDIQTETLFKKIDWASSGAINWDEFCTYMQLEYAEKEETYLKAREMAFCLPARIENTPHRENVIRITSTSDGSFIAGSTDGILSFWSNTLELKKCKSVVTIEQSQRVKSKWIIDFLIMNEFNKIIVATGDREIEFFELSSFEPYCRIHSLENVPLCLDYYVDKDNLDDCLILWGDRKGCVNILHLHATGECLRTWKKQPRSEGIAGIGMENVLSNPSIKFYRWKVHNDWVLKLKYYDSLRQIISCSNDEATALVIGCVEGSTQLDQQMKLKSMHQTKSKDMTFGNMLQPKRRISTDQTVFNIYKGIQTFDFGKSKNVLVTGGLDRIIRLWNPYVNSKPTGMLRGHNKPLVYVHIAEQENRIFSICADKCVKVWDLHDHNCLLTVRPKGHRIRGDMQSCHYSDFAKSLMIATDQVSMLNIKI                                     PVLHTDVAVTHKDPVTCCKYNEAFNQVVTCCEGSTVKLWNLSTGEKVFEFNEAHEDSGVTCLTFDSTGRRLLTGGRDGMVRMWNFNNGHCLTELKKEESDLKYAEISAVEYVEISRNKFIVSVGWDRAINVYIDQCEPGMHKSYYPQSRWLDDMSNGHKEDILTLATLKGHLLATADYHGTIIVWNLMSGHVFFKLISPVADLDEDTDYIDEDLSINKLLFLQSRAKNKSSASLVASGPYGLVHFWNVKEGGILYGRFKGGTESGQSLTAMIACKDQDIDDKLLFIGDRFGFISVWDIENYANNKVETDCPELLRRWRAHVSSITSLDLVLQSQVLITSSDDCTVRVWTFEGEYVGTFGQTEMWDLTNPKTFQHPMVPYDVLVHPQSLPDHPVLGPRMTIEQRKEQSKAESTHKAKMTKQHALQSENSTFTHKNVIYIDDEEINQQIEQKIYKEGKGKRLRFERMKPRNALSEDGGPNEYRSLQVFELAKTPSPRQPEILNQKK
Sbjct:    1 MSSVRVPIGGPVIKPSKIKIRPSSASGNIQTHQSYTTGLYDKKCLFLKDKIKESLPDSNKLKKAGTHIGFLKESQRIIEPKDEIRKPRRRTIEIVDGMDITKFIGREMSLSLRKHNLLDKIEERIDLTVLEELKAAFENAEYDRSGKLDLSEFKALLKEKLQLPTFEDIQTETLFKKIDWASSGAINWDEFCTYMQLEYAEKEETYLKAREMAFCLPARIENTPHRENVIRITSTSDGSFIAGSTDGILSFWSNTLELKKCKSVVTIEQSQRVKSKWIIDFLIMNEFNKIIVATGDREIEFFELSSFEPYCRIHSLENVPLCLDYYVDKDNLDDCLILWGDRKGCVNILHLHATGECLRTWKKQPRSEGIAGIGMENVLSNPSIKFYRWKVHNDWVLKLKYYDSLRQIISCSNDEATALVIGCVEGSTQLDQQMKLKSMHQTKSKDMTFGNMLQPKRRISTDQTVFNIYKGIQTFDFGKSKNVLVTGGLDRIIRLWNPYVNSKPTGMLRGHNKPLVYVHIAEQENRIFSICADKCVKVWDLHDHNCLLTVRPKGHRIRGDMQSCHYSDFAKSLMIATDQVSMLNIKIK------------------------------------PVLHTDVAVTHKDPVTCCKYNEAFNQVVTCCEGSTVKLWNLSTGEKVFEFNEAHEDSGVTCLTFDSTGRRLLTGGRDGMVRMWNFNNGHCLTELKKEESDLKYAEISAVEYVEISRNKFIVSVGWDRAINVYIDQCEPGMHKSYYPQSRWLDDMSNGHKEDILTLATLKGHLLATADYHGTIIVWNLMSGHVFFKLISPVADLDEDTDYIDEDLSINKLLFLQSRAKNKSSASLVASGPYGLVHFWNVKEGGILYGRFKGGTESGQSLTAMIACKDQDIDDKLLFIGDRFGFISVWDIENYANNKVETDCPELLRRWRAHVSSITSLDLVLQSQVLITSSDDCTVRVWTFEGEYVGTFGQTEMWDLTNPKTFQHPMVPYDVLVHPQSLPDHPVLGPRMTIEQRKEQSKAESTHKAKMTKQHALQSENSTFTHKNVIYIDDEEINQQIEQKIYKEGKGKRLRFERMKPRNALSEDGGPNEYRSLQVFELAKTPSPRQPEILNQKK 1092          

Query:  413 DKIEERIDLTVLEELKAAF-ENAEYDRSGKLDLSEFKALLKEKLQLPTFEDIQTETLFKKIDWASSGAINWDEFCTYMQLEYAEKEETYLKAREMAFCLPARIE----NTPHRENVIRITSTSD-GSFIAGSTDGILSFWSNTLELKKCKSVVTIEQSQRVKSKWIIDFLIMNEFNKIIVATGDREIEFFELS---SFEPYCRIHSLENVPLCLDYYVDKDNLDDCLILWGDRKGCVNILHLHATGECL--RTWKKQPRSEGIAGIGMENVLSNPSIK---FYRWKVHNDWVLKLKYYDSLRQIISCSNDEATALVIGCVEGSTQLDQQMKLKSMHQTKSKDMTFGNMLQPKRRISTDQTVFNIYKGIQTFDFGKSKNVLVTGGLDRIIRLWNPYVNSKPTGMLRGHNKPLVYVHIAEQENRIFSICADKCVKVWDLHDHNCL---LTVRPKGHRIRGDMQSCHYSDFAKSLMIATDQVSMLNIKINPFVAEKQLDERHQRASYLGGCYFEQISQNTVLVNKPPVLHTDVAVTHKDPVTCCKYNEAFNQVVTCCEGSTVKLWNLSTGEKVFEFNE-AHEDSGVTCLTFDSXXXXXXXXXXDGMVRMWNFNNGHCLTELKKEESDLKYAEISAVEYVEISRNKFIVSVGWDRAINVYIDQCEPGMHKSYYPQSRWLDDMSNGHKEDILTLATLKGHLLATADYHGTIIVWNLMS 2497
            +K+E ++++  LE L+ AF  +  ++RS   +  EF   L   L   T E+     LF KID    G ++W++F ++M LE+ EK++     R  +  LP   E    + PH++ + RI    +   ++  S +G +  W +  +L+K     T  +S R +  W+ DF  +   NK+ V+   +EI F++++    F    ++ +L  +P+C+DY+   DN  + ++ WGD  G +N++        L  R   K    +    I   N + + SIK   ++  K H DWV K+ Y  +L   +SC+ +  T++VI  +E     +      S     SKD    ++  P+ R  +  + F +++GI +F + ++ N++ T G++  + LWNPYV SKP G+LRGH   +  V   +    + S   DK +++WD+    C+     V PKG            S      +I   ++     K+  F+            ++  G         T+L  KP V   D   +H+ P+  C YN  +NQVVT C+G  +  W + TG++V    E     + +TC+T DST  RL TG  DG V++W+F NGHC   L     +    +IS +  ++    + ++  G+ ++I  +          S  P   W    +  HK+DIL+ A++  H +AT  Y G II+WN+ S
Sbjct:   16 NKLELKLNIKDLETLQEAFFMDGSHNRSQHFNGEEFVEALSLVLCKGTREEYSD--LFDKIDITREGYVDWEKFASHMLLEFYEKDD-----RTKSSSLPQWKELKTLSGPHKDVIQRIVLVRNLNRYLTISKEGNVGLWGSDCKLQKVAKTHT--ESCRSRDLWVTDFAFLGNVNKVAVSFTSKEISFYDMNVKLEFNCQVKLENLFRIPICMDYWHHPDNNGEAIMAWGDTGGYINVILWSNISSSLFERVSSKASDKDENTIIISINDIIHGSIKTCTYFSHKAHQDWVRKVSYIPNLECFVSCATNWNTSMVICWMEKYNPSNS----TSSEMAGSKDEFISDI--PESRGFSRTSCFTVHQGINSFAYNENLNLIATAGVNFQVCLWNPYVISKPNGLLRGHMASVTDVQFNKARGHLISFSKDKILRIWDVQLQVCIQRYAGVFPKGQE----------SALMNPRIILYSKMFYHEEKLRLFI------------TFNFGL--------TMLEMKPDV--KDKISSHEKPLIGCLYNSLYNQVVTACQGGIIYCWMVDTGQRVKTITEICGPQAELTCITQDSTQTRLYTGATDGNVKIWDF-NGHCYNTLIVANGNP--VDISQIVILK----RCVLVFGFSKSITAFWTSSFKDHKVSPSP---WKGVQT--HKDDILSGASIPPHAVATGSYDGEIIIWNINS 669          

Query:  413 DKIEERIDLTVLEELKAAF-ENAEYDRSGKLDLSEFKALLKEKLQLPTFEDIQTETLFKKIDWASSGAINWDEFCTYMQLEYAEKEETYLKAREMAFCLPARIE----NTPHRENVIRITSTSD-GSFIAGSTDGILSFWSNTLELKKCKSVVTIEQSQRVKSKWIIDFLIMNEFNKIIVATGDREIEFFELS---SFEPYCRIHSLENVPLCLDYYVDKDNLDDCLILWGDRKGCVNILHLHATGECL--RTWKKQPRSEGIAGIGMENVLSNPSIK---FYRWKVHNDWVLKLKYYDSLRQIISCSNDEATALVIGCVEGSTQLDQQMKLKSMHQTKSKDMTFGNMLQPKRRISTDQTVFNIYKGIQTFDFGKSKNVLVTGGLDRIIRLWNPYVNSKPTGMLRGHNKPLVYVHIAEQENRIFSICADKCVKVWDLHDHNCL---LTVRPKGHRIRGDMQSCHYSDFAKSLMIATDQVSMLNIKINPFVAEKQLDERHQRASYLGGCYFEQISQNTVLVNKPPVLHTDVAVTHKDPVTCCKYNEAFNQVVTCCEGSTVKLWNLSTGEKVFEFNE-AHEDSGVTCLTFDSXXXXXXXXXXDGMVRMWNFNNGHCLTELKKEESDLKYAEISAVEYVEISRNKFIVSVGWDRAINVYIDQCEPGMHKSYYPQSRWLDDMSNGHKEDILTLATLKGHLLATADYHGTIIVWNLMS 2497
            +K+E ++++  LE L+ AF  +  ++RS   +  EF   L   L   T E+     LF KID    G ++W++F ++M LE+ EK++     R  +  LP   E    + PH++ + RI    +   ++  S +G +  W +  +L+K     T  +S R +  W+ DF  +   NK+ V+   +EI F++++    F    ++ +L  +P+C+DY+   DN  + ++ WGD  G +N++        L  R   K    +    I   N + + SIK   ++  K H DWV K+ Y  +L   +SC+ +  T++VI  +E     +      S     SKD    ++  P+ R  +  + F +++GI +F + ++ N++ T G++  + LWNPYV SKP G+LRGH   +  V   +    + S   DK +++WD+    C+     V PKG  +   M    Y +    L I        N  +                              T+L  KP V   D   +H+ P+  C YN  +NQVVT C+G  +  W + TG++V    E     + +TC+T DST  RL TG  DG V++W+F NGHC   L     +    +IS +    +   + ++  G+ ++I  +          S  P   W    +  HK+DIL+ A++  H +AT  Y G II+WN+ S
Sbjct:   16 NKLELKLNIKDLETLQEAFFMDGSHNRSQHFNGEEFVEALSLVLCKGTREEYSD--LFDKIDITREGYVDWEKFASHMLLEFYEKDD-----RTKSSSLPQWKELKTLSGPHKDVIQRIVLVRNLNRYLTISKEGNVGLWGSDCKLQKVAKTHT--ESCRSRDLWVTDFAFLGNVNKVAVSFTSKEISFYDMNVKLEFNCQVKLENLFRIPICMDYWHHPDNNGEAIMAWGDTGGYINVILWSNISSSLFERVSSKASDKDENTIIISINDIIHGSIKTCTYFSHKAHQDWVRKVSYIPNLECFVSCATNWNTSMVICWMEKYNPSNS----TSSEMAGSKDEFISDI--PESRGFSRTSCFTVHQGINSFAYNENLNLIATAGVNFQVCLWNPYVISKPNGLLRGHMASVTDVQFNKARGHLISFSKDKILRIWDVQLQVCIQRYAGVFPKGQEMYSKM---FYHEEKLRLFIT------FNFGL------------------------------TMLEMKPDV--KDKISSHEKPLIGCLYNSLYNQVVTACQGGIIYCWMVDTGQRVKTITEICGPQAELTCITQDSTQTRLYTGATDGNVKIWDF-NGHCYNTLIVANGNP--VDISQI----VILKRCVLVFGFSKSITAFWTSSFKDHKVSPSP---WKGVQT--HKDDILSGASIPPHAVATGSYDGEIIIWNINS 660          

Query: 2573 SINKLLFLQSRAKNK--SSASLVASGPYGLVHFWNVKEGGILYGRFKGGTESGQSLTAMIACKDQDIDDKLLFIGDRFGFISVWDIENYANNKVET----DCPELLRRWRAHVSSITSLDLVLQ--SQVLITSSDDCTVRVWTFEGEYVGTFGQTEMWDL 3028
            +I++L++L+SR K K    A+L++ G  G+V FWN  EG ++ G F     +   +       + D+ ++ L  GD  G+I VWDI +Y   + E       P L+ +W++H   I+ +    +    ++ITSS D +  +W   G  +G FGQ   W L
Sbjct:  761 NISRLIYLESRKKIKHGGGANLISCGGNGIVRFWNSAEGWLI-GEFVAHENASNIIM------NTDVSNQYLVTGDMDGYIRVWDILSYCQTESENQKIMSPPTLISQWQSHSDEISGISFCFKFSRTLIITSSADQSAALWELNGVLIGRFGQEHRWKL 913          

Query:  413 DKIEERIDLTVLEELKAAF-ENAEYDRSGKLDLSEFKALLKEKLQLPTFEDIQTETLFKKIDWASSGAINWDEFCTYMQLEYAEKEETYLKAREMAFCLPARIE----NTPHRENVIRITSTSD-GSFIAGSTDGILSFWSNTLELKKCKSVVTIEQSQRVKSKWIIDFLIMNEFNKIIVATGDREIEFFELS---SFEPYCRIHSLENVPLCLDYYVDKDNLDDCLILWGDRKGCVNILHLHATGECL--RTWKKQPRSEGIAGIGMENVLSNPSIK---FYRWKVHNDWVLKLKYYDSLRQIISCSNDEATALVIGCVEGSTQLDQQMKLKSMHQTKSKDMTFGNMLQPKRRISTDQTVFNIYKGIQTFDFGKSKNVLVTGGLDRIIRLWNPYVNSKPTGMLRGHNKPLVYVHIAEQENRIFSICADKCVKVWDLHDHNCLLTVRPKGHRIRGDMQSCHYSDFAKSLMIATDQVSMLNIKINPFVAEKQLDERHQRASYLGGCYFEQISQNTVLVNKPPVLHTDVAVTHKDPVTCCKYNEAFNQVVTCCEGSTVKLWNLSTGEKVFEFNE-AHEDSGVTCLTFDSXXXXXXXXXXDGMVRMWNFNNGHCLTELKKEESDLKYAEISAVEYVEISRNKFIVSVGWDRAINVYIDQCEPGMHKSYYPQSRWLDDMSNGHKEDILTLATLKGHLLATADYHGTIIVWNLMS 2497
            +K+E ++++  LE L+ AF  +  ++RS   +  EF   L   L   T E+     LF KID    G ++W++F ++M LE+ EK++     R  +  LP   E    + PH++ + RI    +   ++  S +G +  W +  +L+K     T  +S R +  W+ DF  +   NK+ V+   +EI F++++    F    ++ +L  +P+C+DY+   DN  + ++ WGD  G +N++        L  R   K    +    I   N + + SIK   ++  K H DWV K+ Y  +L   +SC+ +  T++VI  +E     +      S     SKD    ++  P+ R  +  + F +++GI +F + ++ N++ T G++  + LWNPYV SKP G+LRGH   +  V   +    + S   DK +++WD+    C+        R  G       S      +I   ++     K+  F+            ++  G         T+L  KP V   D   +H+ P+  C YN  +NQVVT C+G  +  W + TG++V    E     + +TC+T DST  RL TG  DG V++W+F NGHC   L     +    +IS +    +   + ++  G+ ++I  +          S  P   W    +  HK+DIL+ A++  H +AT  Y G II+WN+ S
Sbjct:   16 NKLELKLNIKDLETLQEAFFMDGSHNRSQHFNGEEFVEALSLVLCKGTREEYSD--LFDKIDITREGYVDWEKFASHMLLEFYEKDD-----RTKSSSLPQWKELKTLSGPHKDVIQRIVLVRNLNRYLTISKEGNVGLWGSDCKLQKVAKTHT--ESCRSRDLWVTDFAFLGNVNKVAVSFTSKEISFYDMNVKLEFNCQVKLENLFRIPICMDYWHHPDNNGEAIMAWGDTGGYINVILWSNISSSLFERVSSKASDKDENTIIISINDIIHGSIKTCTYFSHKAHQDWVRKVSYIPNLECFVSCATNWNTSMVICWMEKYNPSNS----TSSEMAGSKDEFISDI--PESRGFSRTSCFTVHQGINSFAYNENLNLIATAGVNFQVCLWNPYVISKPNGLLRGHMASVTDVQFNKARGHLISFSKDKILRIWDVQLQVCI-------QRYAGVFPKGQESALMNPRIILYSKMFYHEEKLRLFI------------TFNFGL--------TMLEMKPDV--KDKISSHEKPLIGCLYNSLYNQVVTACQGGIIYCWMVDTGQRVKTITEICGPQAELTCITQDSTQTRLYTGATDGNVKIWDF-NGHCYNTLIVANGNP--VDISQI----VILKRCVLVFGFSKSITAFWTSSFKDHKVSPSP---WKGVQT--HKDDILSGASIPPHAVATGSYDGEIIIWNINS 669          

Query: 2573 SINKLLFLQSRAKNK--SSASLVASGPYGLVHFWNVKEGGILYGRFKGGTESGQSLTAMIACKDQDIDDKLLFIGDRFGFISVWDIENYANNKVET----DCPELLRRWRAHVSSITSLDLVLQ--SQVLITSSDDCTVRVWTFEGEYVGTFGQTEMWDL 3028
            +I++L++L+SR K K    A+L++ G  G+V FWN  EG ++ G F     +   +       + D+ ++ L  GD  G+I VWDI +Y   + E       P L+ +W++H   I+ +    +    ++ITSS D +  +W   G  +G FGQ   W L
Sbjct:  764 NISRLIYLESRKKIKHGGGANLISCGGNGIVRFWNSAEGWLI-GEFVAHENASNIIM------NTDVSNQYLVTGDMDGYIRVWDILSYCQTESENQKIMSPPTLISQWQSHSDEISGISFCFKFSRTLIITSSADQSAALWELNGVLIGRFGQEHRWKL 916