Cyclin-C

Overview


Name	Cyclin-C
Smed ID	SMED30017453
Length (bp)	997

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of Cyclin-C (SMED30017453) t-SNE clustered cells

Violin plots show distribution of expression levels for Cyclin-C (SMED30017453) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Cyclin-C (SMED30017453) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Cyclin-C (SMED30017453) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30017453

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 4

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
posterior side	SMED30017453	SMESG000028921.1	dd_Smed_v4_4978_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
posterior muscle cell	SMED30017453	SMESG000028921.1	dd_Smed_v4_4978_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30017453	SMESG000028921.1 SMESG000028920.1	Contig48849	newmark_ests	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30017453	SMESG000028921.1 SMESG000028920.1	Contig48849	uc_Smed_v2	PMID:29674431 Fincher et al., 2018

Note: Hover over icons to view figure legend

Homology

[Close]

BLAST of Cyclin-C vs. Ensembl Human
Match: CCNC (cyclin C [Source:HGNC Symbol;Acc:HGNC:1581])

HSP 1 Score: 147.517 bits (371), Expect = 6.480e-73
Identity = 74/119 (62.18%), Postives = 88/119 (73.95%), Query Frame = 1

Query:   13 MAGNFWRSSHCLEWLLDKQYVLKNRESDIKELGGEDEYQKLMIFFTGVTFSFGEKLGLRQQVIATAVTYFKRFYAMYSLKSVDPWLMGQTALFLASKIEEFGLVSQKSIIQTCNSLNKN 369
            MAGNFW+SSH L+W+LDKQ +LK R+ D+K L  E+EY KL IFFT V  + GE L LRQQVIATA  YFKRFYA YSLKS+DP LM  T +FLASK+EEFG+VS   +I    S+ K 
Sbjct:    1 MAGNFWQSSHYLQWILDKQDLLKERQKDLKFLS-EEEYWKLQIFFTNVIQALGEHLKLRQQVIATATVYFKRFYARYSLKSIDPVLMAPTCVFLASKVEEFGVVSNTRLIAAATSVLKT 118

HSP 2 Score: 147.517 bits (371), Expect = 6.480e-73
Identity = 67/151 (44.37%), Postives = 105/151 (69.54%), Query Frame = 3

Query:  357 FKQKFSQYFPREYPHKIQDVLDCEFILVEVLDCSLIVFHPYRSLLLYSENLSTSPNYQHDSSILQKAWKIVNDSLRTDLMLYYPPYLISLGCLFLACVMDKKNEEAIQSWFADLLVDFSKVMEVVKTMTGLYCLWKNCDDDKDIFNLLSKM 809
             K +FS  FP+E+P+++  +L+CEF L+E++DC LIV+HPYR LL Y +++        +  +L  AW+IVND+ RTDL L YPP++I+L CL +ACV+ +K+    + WFA+L VD  K++E+++ +  LY  WKN D+ K++  +LSKM
Sbjct:  116 LKTRFSYAFPKEFPYRMNHILECEFYLLELMDCCLIVYHPYRPLLQYVQDMG------QEDMLLPLAWRIVNDTYRTDLCLLYPPFMIALACLHVACVVQQKDA---RQWFAELSVDMEKILEIIRVILKLYEQWKNFDERKEMATILSKM 257

[Close]

Query:   13 MAGNFWRSSHCLEWLLDKQYVLKNRESDIKELGGEDEYQKLMIFFTGVTFSFGEKLGLRQQVIATAVTYFKRFYAMYSLKSVDPWLMGQTALFLASKIEEFGLVSQKSIIQTCNSLNKN 369
            MAGNFW+SSH L+W+LDKQ +LK R+ D+K L  E+EY KL IFFT V  + GE L LRQQVIATA  YFKRFYA YSLKS+DP LM  T +FLASK+EEFG+VS   +I    S+ K 
Sbjct:    1 MAGNFWQSSHYLQWILDKQDLLKERQKDLKFLS-EEEYWKLQIFFTNVIQALGEHLKLRQQVIATATVYFKRFYARYSLKSIDPVLMAPTCVFLASKVEEFGVVSNTRLIAAATSVLKT 118

HSP 2 Score: 147.517 bits (371), Expect = 6.480e-73
Identity = 67/151 (44.37%), Postives = 105/151 (69.54%), Query Frame = 3

Query:  357 FKQKFSQYFPREYPHKIQDVLDCEFILVEVLDCSLIVFHPYRSLLLYSENLSTSPNYQHDSSILQKAWKIVNDSLRTDLMLYYPPYLISLGCLFLACVMDKKNEEAIQSWFADLLVDFSKVMEVVKTMTGLYCLWKNCDDDKDIFNLLSKM 809
             K +FS  FP+E+P+++  +L+CEF L+E++DC LIV+HPYR LL Y +++        +  +L  AW+IVND+ RTDL L YPP++I+L CL +ACV+ +K+    + WFA+L VD  K++E+++ +  LY  WKN D+ K++  +LSKM
Sbjct:  116 LKTRFSYAFPKEFPYRMNHILECEFYLLELMDCCLIVYHPYRPLLQYVQDMG------QEDMLLPLAWRIVNDTYRTDLCLLYPPFMIALACLHVACVVQQKDA---RQWFAELSVDMEKILEIIRVILKLYEQWKNFDERKEMATILSKM 257

[Close]

BLAST of Cyclin-C vs. Ensembl Human
Match: CCNC (cyclin C [Source:HGNC Symbol;Acc:HGNC:1581])

HSP 1 Score: 147.517 bits (371), Expect = 9.812e-73
Identity = 67/151 (44.37%), Postives = 105/151 (69.54%), Query Frame = 3

Query:  357 FKQKFSQYFPREYPHKIQDVLDCEFILVEVLDCSLIVFHPYRSLLLYSENLSTSPNYQHDSSILQKAWKIVNDSLRTDLMLYYPPYLISLGCLFLACVMDKKNEEAIQSWFADLLVDFSKVMEVVKTMTGLYCLWKNCDDDKDIFNLLSKM 809
             K +FS  FP+E+P+++  +L+CEF L+E++DC LIV+HPYR LL Y +++        +  +L  AW+IVND+ RTDL L YPP++I+L CL +ACV+ +K+    + WFA+L VD  K++E+++ +  LY  WKN D+ K++  +LSKM
Sbjct:  116 LKTRFSYAFPKEFPYRMNHILECEFYLLELMDCCLIVYHPYRPLLQYVQDMG------QEDMLLPLAWRIVNDTYRTDLCLLYPPFMIALACLHVACVVQQKDA---RQWFAELSVDMEKILEIIRVILKLYEQWKNFDERKEMATILSKM 257

HSP 2 Score: 146.747 bits (369), Expect = 9.812e-73
Identity = 74/119 (62.18%), Postives = 88/119 (73.95%), Query Frame = 1

Query:   13 MAGNFWRSSHCLEWLLDKQYVLKNRESDIKELGGEDEYQKLMIFFTGVTFSFGEKLGLRQQVIATAVTYFKRFYAMYSLKSVDPWLMGQTALFLASKIEEFGLVSQKSIIQTCNSLNKN 369
            MAGNFW+SSH L+W+LDKQ +LK R+ D+K L  E+EY KL IFFT V  + GE L LRQQVIATA  YFKRFYA YSLKS+DP LM  T +FLASK+EEFG+VS   +I    S+ K 
Sbjct:    1 MAGNFWQSSHYLQWILDKQDLLKERQKDLKFLS-EEEYWKLQIFFTNVIQALGEHLKLRQQVIATATVYFKRFYARYSLKSIDPVLMAPTCVFLASKVEEFGVVSNTRLIAAATSVLKT 118

[Close]

BLAST of Cyclin-C vs. Ensembl Human
Match: CCNC (cyclin C [Source:HGNC Symbol;Acc:HGNC:1581])

HSP 1 Score: 146.747 bits (369), Expect = 4.482e-71
Identity = 74/119 (62.18%), Postives = 88/119 (73.95%), Query Frame = 1

Query:   13 MAGNFWRSSHCLEWLLDKQYVLKNRESDIKELGGEDEYQKLMIFFTGVTFSFGEKLGLRQQVIATAVTYFKRFYAMYSLKSVDPWLMGQTALFLASKIEEFGLVSQKSIIQTCNSLNKN 369
            MAGNFW+SSH L+W+LDKQ +LK R+ D+K L  E+EY KL IFFT V  + GE L LRQQVIATA  YFKRFYA YSLKS+DP LM  T +FLASK+EEFG+VS   +I    S+ K 
Sbjct:    1 MAGNFWQSSHYLQWILDKQDLLKERQKDLKFLS-EEEYWKLQIFFTNVIQALGEHLKLRQQVIATATVYFKRFYARYSLKSIDPVLMAPTCVFLASKVEEFGVVSNTRLIAAATSVLKT 118

HSP 2 Score: 141.739 bits (356), Expect = 4.482e-71
Identity = 67/151 (44.37%), Postives = 104/151 (68.87%), Query Frame = 3

Query:  357 FKQKFSQYFPREYPHKIQDVLDCEFILVEVLDCSLIVFHPYRSLLLYSENLSTSPNYQHDSSILQKAWKIVNDSLRTDLMLYYPPYLISLGCLFLACVMDKKNEEAIQSWFADLLVDFSKVMEVVKTMTGLYCLWKNCDDDKDIFNLLSKM 809
             K +FS  FP+E+P+++  +L+CEF L+E++DC LIV+HPYR LL Y +++        +  +L  AW IVND+ RTDL L YPP++I+L CL +ACV+ +K+    + WFA+L VD  K++E+++ +  LY  WKN D+ K++  +LSKM
Sbjct:  116 LKTRFSYAFPKEFPYRMNHILECEFYLLELMDCCLIVYHPYRPLLQYVQDMG------QEDMLLPLAW-IVNDTYRTDLCLLYPPFMIALACLHVACVVQQKDA---RQWFAELSVDMEKILEIIRVILKLYEQWKNFDERKEMATILSKM 256

[Close]

BLAST of Cyclin-C vs. Ensembl Human
Match: CCNC (cyclin C [Source:HGNC Symbol;Acc:HGNC:1581])

HSP 1 Score: 147.132 bits (370), Expect = 3.418e-57
Identity = 74/119 (62.18%), Postives = 88/119 (73.95%), Query Frame = 1

Query:   13 MAGNFWRSSHCLEWLLDKQYVLKNRESDIKELGGEDEYQKLMIFFTGVTFSFGEKLGLRQQVIATAVTYFKRFYAMYSLKSVDPWLMGQTALFLASKIEEFGLVSQKSIIQTCNSLNKN 369
            MAGNFW+SSH L+W+LDKQ +LK R+ D+K L  E+EY KL IFFT V  + GE L LRQQVIATA  YFKRFYA YSLKS+DP LM  T +FLASK+EEFG+VS   +I    S+ K 
Sbjct:    1 MAGNFWQSSHYLQWILDKQDLLKERQKDLKFLS-EEEYWKLQIFFTNVIQALGEHLKLRQQVIATATVYFKRFYARYSLKSIDPVLMAPTCVFLASKVEEFGVVSNTRLIAAATSVLKT 118

HSP 2 Score: 95.1301 bits (235), Expect = 3.418e-57
Identity = 42/89 (47.19%), Postives = 64/89 (71.91%), Query Frame = 3

Query:  360 KQKFSQYFPREYPHKIQDVLDCEFILVEVLDCSLIVFHPYRSLLLYSENLSTSPNYQHDSSILQKAWKIVNDSLRTDLMLYYPPYLISL 626
            K +FS  FP+E+P+++  +L+CEF L+E++DC LIV+HPYR LL Y +++        +  +L  AW+IVND+ RTDL L YPP++I+L
Sbjct:  117 KTRFSYAFPKEFPYRMNHILECEFYLLELMDCCLIVYHPYRPLLQYVQDMG------QEDMLLPLAWRIVNDTYRTDLCLLYPPFMIAL 199

[Close]

BLAST of Cyclin-C vs. Ensembl Celegans
Match: cic-1 (Cyclin-C [Source:UniProtKB/Swiss-Prot;Acc:Q9TYP2])

HSP 1 Score: 96.6709 bits (239), Expect = 8.223e-23
Identity = 64/178 (35.96%), Postives = 93/178 (52.25%), Query Frame = 1

Query:   13 MAGNFWRSSHCLEWLLDKQYVLKNRESDIKELGGEDEYQKLMIFFTGVTFSFGEK---------LGLRQQVIATAVTYFKRFYAMYSLKSVDPWLMGQTALFLASKIEEFGLVSQKSIIQTCNSLNKNSPNISPENILIKFKMYWTVNLS*LKSWIVL*LCFIHTDLYSCILKISLHH 519
            MA NFW+SSHC +W+ DK  + K R  D+K +  E+EY +L IF+     +   +           LRQQVIATA+ YFKRFY   S + + P+L+  TALFLA K+EE   +S  S +       KN+  + P+   + F+   T      K+ +V    FI  ++  C L +  HH
Sbjct:    1 MALNFWKSSHCQQWIFDKTEIWKQRAEDMK-IYNEEEYNRLNIFWANFITAVATEGAHSQANVGCKLRQQVIATAIIYFKRFYLRQSFRDMCPFLVASTALFLACKVEEHTTLSVSSFL-------KNTAIVLPKRWGVTFETTST------KNGVVYDSEFILVEILDCCLVV--HH 162

HSP 2 Score: 94.3597 bits (233), Expect = 5.211e-22
Identity = 52/143 (36.36%), Postives = 85/143 (59.44%), Query Frame = 3

Query:  414 VLDCEFILVEVLDCSLIVFHPYRSLLLYSENL------STSPN--YQHDSSILQKAWKIVNDSLRTDLMLYYPPYLISLGCLFLACVMDKKNEEAIQSWFADLLVDFSKVMEVVKTMTGLYCLWKNCDDDKDIFNLLSKMPKP 818
            V D EFILVE+LDC L+V H  R +    E+L      ST  N   +   +I  +  K+ NDSLR D+ L +PP++I L  + +A  +  + EE +++W  ++  DF KV + V+ +  +Y LWK+ D+ +++  L++K+PKP
Sbjct:  143 VYDSEFILVEILDCCLVVHHASRPMFELLEDLKQFTQQSTIANQPIKDLEAIEAQCQKVANDSLRCDVSLIFPPHVIGLSSIMVAMELMGRGEE-LEAWLVEVDTDFEKVTDCVEQIYKMYTLWKSFDEKEEVKKLMAKLPKP 284

[Close]

BLAST of Cyclin-C vs. Ensembl Celegans
Match: cyl-1 (cyclin L [Source:UniProtKB/TrEMBL;Acc:G5EBX3])

HSP 1 Score: 58.5362 bits (140), Expect = 2.359e-9
Identity = 36/120 (30.00%), Postives = 57/120 (47.50%), Query Frame = 3

Query:  408 QDVLDCEFILVEVLDCSLIVFHPYRSLLLYSENLSTSPNYQHDSSILQKAWKIVNDSLRTDLMLYYPPYLISLGCLFLACVMDKKNEEAIQS----WFADLLVDFSKVMEVVKTMTGLYC 755
            Q +++ E  ++  L   + V HP+R ++ Y   L  +   Q    ILQ++W  +ND LRTD+ + Y P  I+  C+FLA     +N  A+ S    WF         V  +   + GLY 
Sbjct:  214 QHMINSERRILATLGFVVHVKHPHRLIVAYGHTLGIT---QSRPDILQRSWNYMNDGLRTDIFMRYKPETIACACIFLAA-RTVENPIALPSTPFHWFEAFDTSDRDVEAIALQLVGLYA 329

[Close]

Query:  408 QDVLDCEFILVEVLDCSLIVFHPYRSLLLYSENLSTSPNYQHDSSILQKAWKIVNDSLRTDLMLYYPPYLISLGCLFLACVMDKKNEEAIQS----WFADLLVDFSKVMEVVKTMTGLYC 755
            Q +++ E  ++  L   + V HP+R ++ Y   L  +   Q    ILQ++W  +ND LRTD+ + Y P  I+  C+FLA     +N  A+ S    WF         V  +   + GLY 
Sbjct:  214 QHMINSERRILATLGFVVHVKHPHRLIVAYGHTLGIT---QSRPDILQRSWNYMNDGLRTDIFMRYKPETIACACIFLAA-RTVENPIALPSTPFHWFEAFDTSDRDVEAIALQLVGLYA 329

[Close]

BLAST of Cyclin-C vs. Ensembl Celegans
Match: ccnk-1 (CyCliN K [Source:UniProtKB/TrEMBL;Acc:O17869])

HSP 1 Score: 40.4318 bits (93), Expect = 1.112e-8
Identity = 27/85 (31.76%), Postives = 45/85 (52.94%), Query Frame = 3

Query:  390 EYPHKIQDVLDCEFILVEVLDCSLIVFHPYRSLLLYSENLSTSPNYQHDSSILQKAWKIVNDSLRTDLMLYYPPYLISLGCLFLA 644
            +Y + + DV+  E +L+  L   L V  PY +LL Y + +    N +  +  +Q AW  +NDS+ T L +   P +I++  L LA
Sbjct:  111 KYQNLVDDVMGLERVLLHSLKFDLHVALPYDALLDY-KMMFPDMNREKITDAVQIAWTFINDSIYTTLCITTEPQMIAIALLHLA 194

HSP 2 Score: 37.3502 bits (85), Expect = 1.112e-8
Identity = 20/64 (31.25%), Postives = 30/64 (46.88%), Query Frame = 1

Query:  190 QQVIATAVTYFKRFYAMYSLKSVDPWLMGQTALFLASKIEEFGLVSQKSIIQTCNSLNKNSPNI 381
            +  I  A  YF RFY ++S +S    +   + LFLA K+E+F     K     C +   + P I
Sbjct:   49 RPTIGVAAVYFHRFYMIHSFQSFSREVTALSCLFLAGKVEDFP----KKCKDVCQAAVTHYPEI 108

[Close]

Query:  390 EYPHKIQDVLDCEFILVEVLDCSLIVFHPYRSLLLYSENLSTSPNYQHDSSILQKAWKIVNDSLRTDLMLYYPPYLISLGCLFLA 644
            +Y + + DV+  E +L+  L   L V  PY +LL Y + +    N +  +  +Q AW  +NDS+ T L +   P +I++  L LA
Sbjct:  111 KYQNLVDDVMGLERVLLHSLKFDLHVALPYDALLDY-KMMFPDMNREKITDAVQIAWTFINDSIYTTLCITTEPQMIAIALLHLA 194

HSP 2 Score: 37.3502 bits (85), Expect = 1.112e-8
Identity = 20/64 (31.25%), Postives = 30/64 (46.88%), Query Frame = 1

Query:  190 QQVIATAVTYFKRFYAMYSLKSVDPWLMGQTALFLASKIEEFGLVSQKSIIQTCNSLNKNSPNI 381
            +  I  A  YF RFY ++S +S    +   + LFLA K+E+F     K     C +   + P I
Sbjct:   49 RPTIGVAAVYFHRFYMIHSFQSFSREVTALSCLFLAGKVEDFP----KKCKDVCQAAVTHYPEI 108

[Close]

BLAST of Cyclin-C vs. Ensembl Fly
Match: CycC (gene:FBgn0004597 transcript:FBtr0083010)

HSP 1 Score: 136.732 bits (343), Expect = 1.904e-65
Identity = 65/115 (56.52%), Postives = 82/115 (71.30%), Query Frame = 1

Query:   13 MAGNFWRSSHCLEWLLDKQYVLKNRESDIKELGGEDEYQKLMIFFTGVTFSFGEKLGLRQQVIATAVTYFKRFYAMYSLKSVDPWLMGQTALFLASKIEEFGLVSQKSIIQTCNS 357
            MAGNFW+SSH  +W+LDK  +L+ R+ D+  L  EDEYQK+ IFF  V    GE+L LRQQVIATA  YFKRFYA  SLK++DP L+  T + LASK+EEFG++S   +I  C S
Sbjct:    1 MAGNFWQSSHSQQWILDKPDLLRERQHDLLALN-EDEYQKVFIFFANVIQVLGEQLKLRQQVIATATVYFKRFYARNSLKNIDPLLLAPTCILLASKVEEFGVISNSRLISICQS 114

HSP 2 Score: 132.109 bits (331), Expect = 1.904e-65
Identity = 67/151 (44.37%), Postives = 99/151 (65.56%), Query Frame = 3

Query:  357 FKQKFSQYFPREYPHKIQDVLDCEFILVEVLDCSLIVFHPYRSLLLYSENLSTSPNYQHDSSILQKAWKIVNDSLRTDLMLYYPPYLISLGCLFLACVMDKKNEEAIQSWFADLLVDFSKVMEVVKTMTGLYCLWKNCDDDKDIFNLLSKM 809
             K KFS  + +E+P++   +L+CEF L+E LDC LIV+ PYR LL   +++        +  +L  +W+IVNDSLRTD+ L YPPY I++ CL +ACV+ +K+  A + WFA+L VD  KV E+V+ +  LY LWK+  +  +I  LLSK+
Sbjct:  116 IKTKFSYAYAQEFPYRTNHILECEFYLLENLDCCLIVYQPYRPLLQLVQDMG------QEDQLLTLSWRIVNDSLRTDVCLLYPPYQIAIACLQIACVILQKD--ATKQWFAELNVDLDKVQEIVRAIVNLYELWKDWKEKDEIQMLLSKI 258

[Close]

BLAST of Cyclin-C vs. Ensembl Fly
Match: CycK (gene:FBgn0025674 transcript:FBtr0344022)

HSP 1 Score: 45.8246 bits (107), Expect = 1.273e-12
Identity = 30/93 (32.26%), Postives = 49/93 (52.69%), Query Frame = 3

Query:  408 QDVLDCEFILVEVLDCSLIVFHPYRSLLLYSENLSTSPNYQHDSSILQKAWKIVNDSLRTDLMLYYPPYLISLGCLFLACVMDKKNEEAIQSW 686
            ++V+  E IL++ +   L V HPY  LL Y++      + Q    ++Q AW  VNDSL T + L + P +I++  + LA  + K     +Q W
Sbjct:  118 EEVMTLERILLQTIKFDLQVEHPYTFLLKYAKCFKG--DQQKLQKMVQMAWNFVNDSLSTVVCLQWEPEIIAVALIHLASKLSKFT---VQDW 205

HSP 2 Score: 45.4394 bits (106), Expect = 1.273e-12
Identity = 25/80 (31.25%), Postives = 36/80 (45.00%), Query Frame = 1

Query:  169 GEKLGLRQQVIATAVTYFKRFYAMYSLKSVDPWLMGQTALFLASKIEEFGLVSQKSIIQTCNSLNKNSPNISPENILIKF 408
            G K+GL    +AT V YF RFY  +S +S   ++     LF A K+EE          + C  + K +  I  +N    F
Sbjct:   41 GTKMGLGHNTMATGVVYFHRFYMFHSFRSFPRYVTACCCLFFAGKVEE--------TPKKCRDIIKTARGILTDNYFYSF 112

[Close]

BLAST of Cyclin-C vs. Ensembl Fly
Match: CycK (gene:FBgn0025674 transcript:FBtr0085942)

HSP 1 Score: 45.8246 bits (107), Expect = 1.273e-12
Identity = 30/93 (32.26%), Postives = 49/93 (52.69%), Query Frame = 3

Query:  408 QDVLDCEFILVEVLDCSLIVFHPYRSLLLYSENLSTSPNYQHDSSILQKAWKIVNDSLRTDLMLYYPPYLISLGCLFLACVMDKKNEEAIQSW 686
            ++V+  E IL++ +   L V HPY  LL Y++      + Q    ++Q AW  VNDSL T + L + P +I++  + LA  + K     +Q W
Sbjct:  118 EEVMTLERILLQTIKFDLQVEHPYTFLLKYAKCFKG--DQQKLQKMVQMAWNFVNDSLSTVVCLQWEPEIIAVALIHLASKLSKFT---VQDW 205

HSP 2 Score: 45.4394 bits (106), Expect = 1.273e-12
Identity = 25/80 (31.25%), Postives = 36/80 (45.00%), Query Frame = 1

Query:  169 GEKLGLRQQVIATAVTYFKRFYAMYSLKSVDPWLMGQTALFLASKIEEFGLVSQKSIIQTCNSLNKNSPNISPENILIKF 408
            G K+GL    +AT V YF RFY  +S +S   ++     LF A K+EE          + C  + K +  I  +N    F
Sbjct:   41 GTKMGLGHNTMATGVVYFHRFYMFHSFRSFPRYVTACCCLFFAGKVEE--------TPKKCRDIIKTARGILTDNYFYSF 112

[Close]

BLAST of Cyclin-C vs. Ensembl Fly
Match: CycK (gene:FBgn0025674 transcript:FBtr0085941)

HSP 1 Score: 45.8246 bits (107), Expect = 1.273e-12
Identity = 30/93 (32.26%), Postives = 49/93 (52.69%), Query Frame = 3

Query:  408 QDVLDCEFILVEVLDCSLIVFHPYRSLLLYSENLSTSPNYQHDSSILQKAWKIVNDSLRTDLMLYYPPYLISLGCLFLACVMDKKNEEAIQSW 686
            ++V+  E IL++ +   L V HPY  LL Y++      + Q    ++Q AW  VNDSL T + L + P +I++  + LA  + K     +Q W
Sbjct:  118 EEVMTLERILLQTIKFDLQVEHPYTFLLKYAKCFKG--DQQKLQKMVQMAWNFVNDSLSTVVCLQWEPEIIAVALIHLASKLSKFT---VQDW 205

HSP 2 Score: 45.4394 bits (106), Expect = 1.273e-12
Identity = 25/80 (31.25%), Postives = 36/80 (45.00%), Query Frame = 1

Query:  169 GEKLGLRQQVIATAVTYFKRFYAMYSLKSVDPWLMGQTALFLASKIEEFGLVSQKSIIQTCNSLNKNSPNISPENILIKF 408
            G K+GL    +AT V YF RFY  +S +S   ++     LF A K+EE          + C  + K +  I  +N    F
Sbjct:   41 GTKMGLGHNTMATGVVYFHRFYMFHSFRSFPRYVTACCCLFFAGKVEE--------TPKKCRDIIKTARGILTDNYFYSF 112

[Close]

BLAST of Cyclin-C vs. Ensembl Fly
Match: CycT (gene:FBgn0025455 transcript:FBtr0333124)

HSP 1 Score: 45.0542 bits (105), Expect = 8.657e-8
Identity = 31/108 (28.70%), Postives = 50/108 (46.30%), Query Frame = 1

Query:   76 LKNRESDIKELGGEDE--YQKLMIFFTGVTFSFGEKLGLRQQVIATAVTYFKRFYAMYSLKSVDPWLMGQTALFLASKIEEFGLVSQKSIIQTCNSLNKNSPNISPEN 393
            L N  S    + G+DE  Y+++  +        G++L + Q  I TA+ Y  RFYA +S        M   +LFLA+K+EE      + +     + NK  P  + +N
Sbjct:   52 LANSPSRRCGIKGDDELQYRQMTAYLIQ---EMGQRLQVSQLCINTAIVYMHRFYAFHSFTHFHRNSMASASLFLAAKVEE----QPRKLEHVIRAANKCLPPTTEQN 152

HSP 2 Score: 30.0314 bits (66), Expect = 8.657e-8
Identity = 25/124 (20.16%), Postives = 62/124 (50.00%), Query Frame = 3

Query:  387 REYPHKIQDVLDCEFILVEVLDCSLIVFHPYRSLLLYSENLSTSPNYQHDSSILQKAWKIVNDSLR-TDLMLYYPPYLISLGCLFLACVMDK----KNEEAIQSWFADLLVDFSKVMEVVKTMT 743
            + Y    Q+++  E +L++ L   + + HP+  ++   + +    +      + Q ++ + ++SL  T + L Y P +++  C++LAC   +    ++ E  + WF    VD +  ++++K +T
Sbjct:  151 QNYAELAQELVFNENVLLQTLGFDVAIDHPHTHVVRTCQLVKACKD------LAQTSYFLASNSLHLTSMCLQYRPTVVACFCIYLACKWSRWEIPQSTEG-KHWF--YYVDKTVSLDLLKQLT 265

[Close]

BLAST of Cyclin-C vs. Ensembl Zebrafish
Match: ccnc (cyclin C [Source:ZFIN;Acc:ZDB-GENE-030131-7369])

HSP 1 Score: 144.05 bits (362), Expect = 6.839e-71
Identity = 72/119 (60.50%), Postives = 87/119 (73.11%), Query Frame = 1

Query:   13 MAGNFWRSSHCLEWLLDKQYVLKNRESDIKELGGEDEYQKLMIFFTGVTFSFGEKLGLRQQVIATAVTYFKRFYAMYSLKSVDPWLMGQTALFLASKIEEFGLVSQKSIIQTCNSLNKN 369
            MAGNFW+SSH L+W+LDKQ ++K R+ D+K L  E+EY KL IFF  V  + GE L LRQQVIATA  YFKRFYA YSLKS+DP LM  T +FLASK+EEFG+VS   +I    S+ K 
Sbjct:    1 MAGNFWQSSHYLQWVLDKQDLMKERQKDLKFLT-EEEYWKLQIFFANVIQALGEHLKLRQQVIATATVYFKRFYARYSLKSIDPVLMAPTCVFLASKVEEFGVVSNTRLISAATSVLKT 118

HSP 2 Score: 143.665 bits (361), Expect = 6.839e-71
Identity = 66/150 (44.00%), Postives = 104/150 (69.33%), Query Frame = 3

Query:  360 KQKFSQYFPREYPHKIQDVLDCEFILVEVLDCSLIVFHPYRSLLLYSENLSTSPNYQHDSSILQKAWKIVNDSLRTDLMLYYPPYLISLGCLFLACVMDKKNEEAIQSWFADLLVDFSKVMEVVKTMTGLYCLWKNCDDDKDIFNLLSKM 809
            K +FS  FP+E+P ++  +L+CEF L+E++DC LIV+HPYR LL Y +++        +  +L  AW+IVND+ RTDL L YPP++I+L CL +ACV+ +K+    + WFA+L VD  K++E+++ +  LY  WKN DD K+I  +++K+
Sbjct:  117 KTRFSYAFPKEFPFRMNHILECEFYLLELMDCCLIVYHPYRPLLQYVQDMG------QEDMLLPLAWRIVNDTYRTDLCLLYPPFMIALACLHVACVVQQKDA---RQWFAELSVDMEKILEIIRVILKLYDQWKNFDDRKEIAAVINKV 257

[Close]

BLAST of Cyclin-C vs. Ensembl Zebrafish
Match: ccnk (cyclin K [Source:NCBI gene;Acc:569432])

HSP 1 Score: 55.4546 bits (132), Expect = 1.060e-16
Identity = 35/103 (33.98%), Postives = 48/103 (46.60%), Query Frame = 1

Query:   52 WLLDKQYVLKNRESDIKELGGEDEYQKLMIFFTGVTFSFGEKLGLRQQVIATAVTYFKRFYAMYSLKSVDPWLMGQTALFLASKIEEFGLVSQKSIIQTCNSL 360
            W  DK+ +         +   E  Y++    F    F  G +LGL    +AT +TYF RFY  +S K    ++ G   LFLA K+EE      K II+T  SL
Sbjct:   26 WYWDKKDLAHTPSQSDLDPATEARYRREGARFI---FDVGTRLGLHYDTLATGITYFHRFYMFHSFKQFPRYVTGACCLFLAGKVEETPKKC-KDIIKTARSL 124

HSP 2 Score: 50.447 bits (119), Expect = 1.060e-16
Identity = 33/93 (35.48%), Postives = 52/93 (55.91%), Query Frame = 3

Query:  408 QDVLDCEFILVEVLDCSLIVFHPYRSLLLYSENLSTSPNYQHDSSILQKAWKIVNDSLRTDLMLYYPPYLISLGCLFLACVMDKKNEEAIQSW 686
            ++V+  E IL++ +   L V HPY+ LL Y++ L    N      ++Q AW  VNDSL T L L + P +I++  ++LA  + K +   IQ W
Sbjct:  139 EEVMVLERILLQTIKFDLQVEHPYQFLLRYAKQLKGDKNKVQ--KLVQMAWTFVNDSLCTMLSLQWEPEIIAVAVMYLAGRLCKFD---IQEW 226

[Close]

BLAST of Cyclin-C vs. Ensembl Zebrafish
Match: ccnk (cyclin K [Source:NCBI gene;Acc:569432])

HSP 1 Score: 55.4546 bits (132), Expect = 1.416e-16
Identity = 35/103 (33.98%), Postives = 48/103 (46.60%), Query Frame = 1

Query:   52 WLLDKQYVLKNRESDIKELGGEDEYQKLMIFFTGVTFSFGEKLGLRQQVIATAVTYFKRFYAMYSLKSVDPWLMGQTALFLASKIEEFGLVSQKSIIQTCNSL 360
            W  DK+ +         +   E  Y++    F    F  G +LGL    +AT +TYF RFY  +S K    ++ G   LFLA K+EE      K II+T  SL
Sbjct:   26 WYWDKKDLAHTPSQSDLDPATEARYRREGARFI---FDVGTRLGLHYDTLATGITYFHRFYMFHSFKQFPRYVTGACCLFLAGKVEETPKKC-KDIIKTARSL 124

HSP 2 Score: 49.6766 bits (117), Expect = 1.416e-16
Identity = 33/93 (35.48%), Postives = 52/93 (55.91%), Query Frame = 3

Query:  408 QDVLDCEFILVEVLDCSLIVFHPYRSLLLYSENLSTSPNYQHDSSILQKAWKIVNDSLRTDLMLYYPPYLISLGCLFLACVMDKKNEEAIQSW 686
            ++V+  E IL++ +   L V HPY+ LL Y++ L    N      ++Q AW  VNDSL T L L + P +I++  ++LA  + K +   IQ W
Sbjct:  139 EEVMVLERILLQTIKFDLQVEHPYQFLLRYAKQLKGDKNKVQ--KLVQMAWTFVNDSLCTMLSLQWEPEIIAVAVMYLAGRLCKFD---IQEW 226

[Close]

BLAST of Cyclin-C vs. Ensembl Zebrafish
Match: ccnq (cyclin Q [Source:NCBI gene;Acc:553650])

HSP 1 Score: 50.8322 bits (120), Expect = 1.822e-7
Identity = 29/83 (34.94%), Postives = 44/83 (53.01%), Query Frame = 1

Query:  109 GGED-EYQKLMIFFTGVTFSFGEKLGLRQQVIATAVTYFKRFYAMYSLKSVDPWLMGQTALFLASKIEEFGLVSQKSIIQTCN 354
              ED EY K            G KLG+R   +ATA   + RF+   SL+  +P+L+  +A++LA K+EE  L + + II  C+
Sbjct:   19 SAEDVEYSKTHFRVCRFITETGVKLGMRSVPMATACVLYHRFFQSASLQIYEPYLVAMSAIYLAGKVEEQHLRT-RDIINVCH 100

HSP 2 Score: 23.8682 bits (50), Expect = 1.822e-7
Identity = 14/69 (20.29%), Postives = 33/69 (47.83%), Query Frame = 3

Query:  411 DVLDCEFILVEVLDCSLIVFHPYRSLLLYSENLSTSPNYQ--HDSSILQKAWKIVNDSLRTDLMLYYPP 611
             ++ CE +++  L+  +   HP++ LL Y  ++ +  N      + I + A  ++ DS    + + + P
Sbjct:  122 SIVQCELLILRQLNFQVTFEHPHKYLLHYLLSVRSLLNRHAWSRTPIAETALAVLKDSYHGSVCVRHRP 190

[Close]

Query:  109 GGED-EYQKLMIFFTGVTFSFGEKLGLRQQVIATAVTYFKRFYAMYSLKSVDPWLMGQTALFLASKIEEFGLVSQKSIIQTCN 354
              ED EY K            G KLG+R   +ATA   + RF+   SL+  +P+L+  +A++LA K+EE  L + + II  C+
Sbjct:   19 SAEDVEYSKTHFRVCRFITETGVKLGMRSVPMATACVLYHRFFQSASLQIYEPYLVAMSAIYLAGKVEEQHLRT-RDIINVCH 100

HSP 2 Score: 23.8682 bits (50), Expect = 1.822e-7
Identity = 14/69 (20.29%), Postives = 33/69 (47.83%), Query Frame = 3

Query:  411 DVLDCEFILVEVLDCSLIVFHPYRSLLLYSENLSTSPNYQ--HDSSILQKAWKIVNDSLRTDLMLYYPP 611
             ++ CE +++  L+  +   HP++ LL Y  ++ +  N      + I + A  ++ DS    + + + P
Sbjct:  122 SIVQCELLILRQLNFQVTFEHPHKYLLHYLLSVRSLLNRHAWSRTPIAETALAVLKDSYHGSVCVRHRP 190

[Close]

BLAST of Cyclin-C vs. Ensembl Xenopus
Match: ccnc (cyclin C [Source:NCBI gene;Acc:394762])

HSP 1 Score: 146.747 bits (369), Expect = 3.053e-72
Identity = 74/119 (62.18%), Postives = 88/119 (73.95%), Query Frame = 1

Query:   13 MAGNFWRSSHCLEWLLDKQYVLKNRESDIKELGGEDEYQKLMIFFTGVTFSFGEKLGLRQQVIATAVTYFKRFYAMYSLKSVDPWLMGQTALFLASKIEEFGLVSQKSIIQTCNSLNKN 369
            MAGNFW+SSH L+W+LDKQ +LK R+ D+K L  E+EY KL IFFT V  + GE L LRQQVIATA  YFKRFYA YSLKS+DP LM  T +FLASK+EEFG+VS   +I    S+ K 
Sbjct:    1 MAGNFWQSSHYLQWILDKQDLLKERQKDLKFLS-EEEYWKLQIFFTNVIQALGEHLKLRQQVIATATVYFKRFYARYSLKSIDPVLMAPTCVFLASKVEEFGVVSNTRLISAATSVLKT 118

HSP 2 Score: 145.976 bits (367), Expect = 3.053e-72
Identity = 66/151 (43.71%), Postives = 105/151 (69.54%), Query Frame = 3

Query:  357 FKQKFSQYFPREYPHKIQDVLDCEFILVEVLDCSLIVFHPYRSLLLYSENLSTSPNYQHDSSILQKAWKIVNDSLRTDLMLYYPPYLISLGCLFLACVMDKKNEEAIQSWFADLLVDFSKVMEVVKTMTGLYCLWKNCDDDKDIFNLLSKM 809
             K +FS  FP+E+P+++  +L+CEF L+E++DC LIV+HPYR LL Y +++        +  +L  AW+IVND+ RTDL L YPP++I+L CL +ACV+ +K+    + WFA+L VD  K++E+++ +  LY  WKN D+ K++  +L+KM
Sbjct:  116 LKTRFSYAFPKEFPYRMNHILECEFYLLELMDCCLIVYHPYRPLLQYVQDMG------QEDMLLPLAWRIVNDTYRTDLCLLYPPFMIALACLHVACVVQQKDA---RQWFAELSVDMEKILEIIRVILKLYEQWKNFDERKEMATILNKM 257

[Close]

BLAST of Cyclin-C vs. Ensembl Xenopus
Match: ccnc (cyclin C [Source:NCBI gene;Acc:394762])

HSP 1 Score: 129.798 bits (325), Expect = 3.750e-60
Identity = 66/109 (60.55%), Postives = 79/109 (72.48%), Query Frame = 1

Query:   43 CLEWLLDKQYVLKNRESDIKELGGEDEYQKLMIFFTGVTFSFGEKLGLRQQVIATAVTYFKRFYAMYSLKSVDPWLMGQTALFLASKIEEFGLVSQKSIIQTCNSLNKN 369
            CL+W+LDKQ +LK R+ D+K L  E+EY KL IFFT V  + GE L LRQQVIATA  YFKRFYA YSLKS+DP LM  T +FLASK+EEFG+VS   +I    S+ K 
Sbjct:    6 CLQWILDKQDLLKERQKDLKFLS-EEEYWKLQIFFTNVIQALGEHLKLRQQVIATATVYFKRFYARYSLKSIDPVLMAPTCVFLASKVEEFGVVSNTRLISAATSVLKT 113

HSP 2 Score: 122.479 bits (306), Expect = 3.750e-60
Identity = 60/151 (39.74%), Postives = 94/151 (62.25%), Query Frame = 3

Query:  357 FKQKFSQYFPREYPHKIQDVLDCEFILVEVLDCSLIVFHPYRSLLLYSENLSTSPNYQHDSSILQKAWKIVNDSLRTDLMLYYPPYLISLGCLFLACVMDKKNEEAIQSWFADLLVDFSKVMEVVKTMTGLYCLWKNCDDDKDIFNLLSKM 809
             K +FS  FP+E+P+++              DC LIV+HPYR LL Y +++        +  +L  AW+IVND+ RTDL L YPP++I+L CL +ACV+ +K+    + WFA+L VD  K++E+++ +  LY  WKN D+ K++  +L+KM
Sbjct:  111 LKTRFSYAFPKEFPYRMNH------------DCCLIVYHPYRPLLQYVQDMG------QEDMLLPLAWRIVNDTYRTDLCLLYPPFMIALACLHVACVVQQKDA---RQWFAELSVDMEKILEIIRVILKLYEQWKNFDERKEMATILNKM 240

[Close]

BLAST of Cyclin-C vs. Ensembl Xenopus
Match: ccnk (cyclin K [Source:NCBI gene;Acc:779776])

HSP 1 Score: 52.373 bits (124), Expect = 6.950e-16
Identity = 37/105 (35.24%), Postives = 48/105 (45.71%), Query Frame = 1

Query:   52 WLLDKQYVLKNRESDIKELGGEDEYQKLMIFFTGVTFSF--GEKLGLRQQVIATAVTYFKRFYAMYSLKSVDPWLMGQTALFLASKIEEFGLVSQKSIIQTCNSL 360
            W  DK    K+      +L G D   +      G  F F  G +LGL    +AT + YF RFY  +S K    ++ G   LFLA K+EE      K II+T  SL
Sbjct:  136 WYWDK----KDLAHTPSQLEGLDPATEARYRREGARFIFDVGTRLGLHYDTLATGIIYFHRFYMFHSFKQFPRYVTGACCLFLAGKVEETPKKC-KDIIKTARSL 235

HSP 2 Score: 51.2174 bits (121), Expect = 6.950e-16
Identity = 34/98 (34.69%), Postives = 53/98 (54.08%), Query Frame = 3

Query:  408 QDVLDCEFILVEVLDCSLIVFHPYRSLLLYSENLSTSPNYQHDSSILQKAWKIVNDSLRTDLMLYYPPYLISLGCLFLACVMDKKNEEAIQSWFADLL 701
            ++V+  E IL++ +   L V HPY+ LL Y++ L    N      ++Q AW  VNDSL T L L + P +I++  ++LA  + K     IQ W +  L
Sbjct:  250 EEVMVLERILLQTIKFDLQVEHPYQFLLRYAKQLKGDKN--KIQKLVQMAWTFVNDSLCTTLSLQWEPEIIAVAVMYLAGRLCKFE---IQEWTSKPL 342

[Close]

BLAST of Cyclin-C vs. Ensembl Xenopus
Match: ccnk (cyclin K [Source:NCBI gene;Acc:779776])

HSP 1 Score: 52.373 bits (124), Expect = 7.384e-16
Identity = 28/67 (41.79%), Postives = 36/67 (53.73%), Query Frame = 1

Query:  160 FSFGEKLGLRQQVIATAVTYFKRFYAMYSLKSVDPWLMGQTALFLASKIEEFGLVSQKSIIQTCNSL 360
            F  G +LGL    +AT + YF RFY  +S K    ++ G   LFLA K+EE      K II+T  SL
Sbjct:   58 FDVGTRLGLHYDTLATGIIYFHRFYMFHSFKQFPRYVTGACCLFLAGKVEETPKKC-KDIIKTARSL 123

HSP 2 Score: 51.2174 bits (121), Expect = 7.384e-16
Identity = 34/98 (34.69%), Postives = 53/98 (54.08%), Query Frame = 3

Query:  408 QDVLDCEFILVEVLDCSLIVFHPYRSLLLYSENLSTSPNYQHDSSILQKAWKIVNDSLRTDLMLYYPPYLISLGCLFLACVMDKKNEEAIQSWFADLL 701
            ++V+  E IL++ +   L V HPY+ LL Y++ L    N      ++Q AW  VNDSL T L L + P +I++  ++LA  + K     IQ W +  L
Sbjct:  138 EEVMVLERILLQTIKFDLQVEHPYQFLLRYAKQLKGDKN--KIQKLVQMAWTFVNDSLCTTLSLQWEPEIIAVAVMYLAGRLCKFE---IQEWTSKPL 230

[Close]

BLAST of Cyclin-C vs. Ensembl Xenopus
Match: ccnk (cyclin K [Source:NCBI gene;Acc:779776])

HSP 1 Score: 51.9878 bits (123), Expect = 7.699e-16
Identity = 28/67 (41.79%), Postives = 36/67 (53.73%), Query Frame = 1

Query:  160 FSFGEKLGLRQQVIATAVTYFKRFYAMYSLKSVDPWLMGQTALFLASKIEEFGLVSQKSIIQTCNSL 360
            F  G +LGL    +AT + YF RFY  +S K    ++ G   LFLA K+EE      K II+T  SL
Sbjct:   58 FDVGTRLGLHYDTLATGIIYFHRFYMFHSFKQFPRYVTGACCLFLAGKVEETPKKC-KDIIKTARSL 123

HSP 2 Score: 51.2174 bits (121), Expect = 7.699e-16
Identity = 34/98 (34.69%), Postives = 53/98 (54.08%), Query Frame = 3

Query:  408 QDVLDCEFILVEVLDCSLIVFHPYRSLLLYSENLSTSPNYQHDSSILQKAWKIVNDSLRTDLMLYYPPYLISLGCLFLACVMDKKNEEAIQSWFADLL 701
            ++V+  E IL++ +   L V HPY+ LL Y++ L    N      ++Q AW  VNDSL T L L + P +I++  ++LA  + K     IQ W +  L
Sbjct:  138 EEVMVLERILLQTIKFDLQVEHPYQFLLRYAKQLKGDKN--KIQKLVQMAWTFVNDSLCTTLSLQWEPEIIAVAVMYLAGRLCKFE---IQEWTSKPL 230

[Close]

BLAST of Cyclin-C vs. Ensembl Mouse
Match: Ccnc (cyclin C [Source:MGI Symbol;Acc:MGI:1858199])

HSP 1 Score: 147.517 bits (371), Expect = 5.787e-73
Identity = 67/151 (44.37%), Postives = 105/151 (69.54%), Query Frame = 3

Query:  357 FKQKFSQYFPREYPHKIQDVLDCEFILVEVLDCSLIVFHPYRSLLLYSENLSTSPNYQHDSSILQKAWKIVNDSLRTDLMLYYPPYLISLGCLFLACVMDKKNEEAIQSWFADLLVDFSKVMEVVKTMTGLYCLWKNCDDDKDIFNLLSKM 809
             K +FS  FP+E+P+++  +L+CEF L+E++DC LIV+HPYR LL Y +++        +  +L  AW+IVND+ RTDL L YPP++I+L CL +ACV+ +K+    + WFA+L VD  K++E+++ +  LY  WKN D+ K++  +LSKM
Sbjct:  116 LKTRFSYAFPKEFPYRMNHILECEFYLLELMDCCLIVYHPYRPLLQYVQDMG------QEDVLLPLAWRIVNDTYRTDLCLLYPPFMIALACLHVACVVQQKDA---RQWFAELSVDMEKILEIIRVILKLYEQWKNFDERKEMATILSKM 257

HSP 2 Score: 147.132 bits (370), Expect = 5.787e-73
Identity = 74/119 (62.18%), Postives = 88/119 (73.95%), Query Frame = 1

Query:   13 MAGNFWRSSHCLEWLLDKQYVLKNRESDIKELGGEDEYQKLMIFFTGVTFSFGEKLGLRQQVIATAVTYFKRFYAMYSLKSVDPWLMGQTALFLASKIEEFGLVSQKSIIQTCNSLNKN 369
            MAGNFW+SSH L+W+LDKQ +LK R+ D+K L  E+EY KL IFFT V  + GE L LRQQVIATA  YFKRFYA YSLKS+DP LM  T +FLASK+EEFG+VS   +I    S+ K 
Sbjct:    1 MAGNFWQSSHYLQWILDKQDLLKERQKDLKFLS-EEEYWKLQIFFTNVIQALGEHLKLRQQVIATATVYFKRFYARYSLKSIDPVLMAPTCVFLASKVEEFGVVSNTRLIAATTSVLKT 118

[Close]

Query:  357 FKQKFSQYFPREYPHKIQDVLDCEFILVEVLDCSLIVFHPYRSLLLYSENLSTSPNYQHDSSILQKAWKIVNDSLRTDLMLYYPPYLISLGCLFLACVMDKKNEEAIQSWFADLLVDFSKVMEVVKTMTGLYCLWKNCDDDKDIFNLLSKM 809
             K +FS  FP+E+P+++  +L+CEF L+E++DC LIV+HPYR LL Y +++        +  +L  AW+IVND+ RTDL L YPP++I+L CL +ACV+ +K+    + WFA+L VD  K++E+++ +  LY  WKN D+ K++  +LSKM
Sbjct:  116 LKTRFSYAFPKEFPYRMNHILECEFYLLELMDCCLIVYHPYRPLLQYVQDMG------QEDVLLPLAWRIVNDTYRTDLCLLYPPFMIALACLHVACVVQQKDA---RQWFAELSVDMEKILEIIRVILKLYEQWKNFDERKEMATILSKM 257

HSP 2 Score: 147.132 bits (370), Expect = 5.787e-73
Identity = 74/119 (62.18%), Postives = 88/119 (73.95%), Query Frame = 1

Query:   13 MAGNFWRSSHCLEWLLDKQYVLKNRESDIKELGGEDEYQKLMIFFTGVTFSFGEKLGLRQQVIATAVTYFKRFYAMYSLKSVDPWLMGQTALFLASKIEEFGLVSQKSIIQTCNSLNKN 369
            MAGNFW+SSH L+W+LDKQ +LK R+ D+K L  E+EY KL IFFT V  + GE L LRQQVIATA  YFKRFYA YSLKS+DP LM  T +FLASK+EEFG+VS   +I    S+ K 
Sbjct:    1 MAGNFWQSSHYLQWILDKQDLLKERQKDLKFLS-EEEYWKLQIFFTNVIQALGEHLKLRQQVIATATVYFKRFYARYSLKSIDPVLMAPTCVFLASKVEEFGVVSNTRLIAATTSVLKT 118

[Close]

BLAST of Cyclin-C vs. Ensembl Mouse
Match: Ccnc (cyclin C [Source:MGI Symbol;Acc:MGI:1858199])

HSP 1 Score: 147.517 bits (371), Expect = 8.065e-73
Identity = 67/151 (44.37%), Postives = 105/151 (69.54%), Query Frame = 3

Query:  357 FKQKFSQYFPREYPHKIQDVLDCEFILVEVLDCSLIVFHPYRSLLLYSENLSTSPNYQHDSSILQKAWKIVNDSLRTDLMLYYPPYLISLGCLFLACVMDKKNEEAIQSWFADLLVDFSKVMEVVKTMTGLYCLWKNCDDDKDIFNLLSKM 809
             K +FS  FP+E+P+++  +L+CEF L+E++DC LIV+HPYR LL Y +++        +  +L  AW+IVND+ RTDL L YPP++I+L CL +ACV+ +K+    + WFA+L VD  K++E+++ +  LY  WKN D+ K++  +LSKM
Sbjct:  116 LKTRFSYAFPKEFPYRMNHILECEFYLLELMDCCLIVYHPYRPLLQYVQDMG------QEDVLLPLAWRIVNDTYRTDLCLLYPPFMIALACLHVACVVQQKDA---RQWFAELSVDMEKILEIIRVILKLYEQWKNFDERKEMATILSKM 257

HSP 2 Score: 146.362 bits (368), Expect = 8.065e-73
Identity = 74/119 (62.18%), Postives = 88/119 (73.95%), Query Frame = 1

Query:   13 MAGNFWRSSHCLEWLLDKQYVLKNRESDIKELGGEDEYQKLMIFFTGVTFSFGEKLGLRQQVIATAVTYFKRFYAMYSLKSVDPWLMGQTALFLASKIEEFGLVSQKSIIQTCNSLNKN 369
            MAGNFW+SSH L+W+LDKQ +LK R+ D+K L  E+EY KL IFFT V  + GE L LRQQVIATA  YFKRFYA YSLKS+DP LM  T +FLASK+EEFG+VS   +I    S+ K 
Sbjct:    1 MAGNFWQSSHYLQWILDKQDLLKERQKDLKFLS-EEEYWKLQIFFTNVIQALGEHLKLRQQVIATATVYFKRFYARYSLKSIDPVLMAPTCVFLASKVEEFGVVSNTRLIAATTSVLKT 118

[Close]

BLAST of Cyclin-C vs. Ensembl Mouse
Match: Ccnc (cyclin C [Source:MGI Symbol;Acc:MGI:1858199])

HSP 1 Score: 147.132 bits (370), Expect = 8.482e-73
Identity = 67/151 (44.37%), Postives = 105/151 (69.54%), Query Frame = 3

Query:  357 FKQKFSQYFPREYPHKIQDVLDCEFILVEVLDCSLIVFHPYRSLLLYSENLSTSPNYQHDSSILQKAWKIVNDSLRTDLMLYYPPYLISLGCLFLACVMDKKNEEAIQSWFADLLVDFSKVMEVVKTMTGLYCLWKNCDDDKDIFNLLSKM 809
             K +FS  FP+E+P+++  +L+CEF L+E++DC LIV+HPYR LL Y +++        +  +L  AW+IVND+ RTDL L YPP++I+L CL +ACV+ +K+    + WFA+L VD  K++E+++ +  LY  WKN D+ K++  +LSKM
Sbjct:  116 LKTRFSYAFPKEFPYRMNHILECEFYLLELMDCCLIVYHPYRPLLQYVQDMG------QEDVLLPLAWRIVNDTYRTDLCLLYPPFMIALACLHVACVVQQKDA---RQWFAELSVDMEKILEIIRVILKLYEQWKNFDERKEMATILSKM 257

HSP 2 Score: 146.747 bits (369), Expect = 8.482e-73
Identity = 74/119 (62.18%), Postives = 88/119 (73.95%), Query Frame = 1

Query:   13 MAGNFWRSSHCLEWLLDKQYVLKNRESDIKELGGEDEYQKLMIFFTGVTFSFGEKLGLRQQVIATAVTYFKRFYAMYSLKSVDPWLMGQTALFLASKIEEFGLVSQKSIIQTCNSLNKN 369
            MAGNFW+SSH L+W+LDKQ +LK R+ D+K L  E+EY KL IFFT V  + GE L LRQQVIATA  YFKRFYA YSLKS+DP LM  T +FLASK+EEFG+VS   +I    S+ K 
Sbjct:    1 MAGNFWQSSHYLQWILDKQDLLKERQKDLKFLS-EEEYWKLQIFFTNVIQALGEHLKLRQQVIATATVYFKRFYARYSLKSIDPVLMAPTCVFLASKVEEFGVVSNTRLIAATTSVLKT 118

[Close]

BLAST of Cyclin-C vs. Ensembl Mouse
Match: Ccnk (cyclin K [Source:MGI Symbol;Acc:MGI:1276106])

HSP 1 Score: 53.9138 bits (128), Expect = 2.730e-16
Identity = 39/119 (32.77%), Postives = 53/119 (44.54%), Query Frame = 1

Query:   10 IMAGNFWRSSHCLEWLLDKQYVLKNRESDIKELGGEDEYQKLMIFFTGVTFSF--GEKLGLRQQVIATAVTYFKRFYAMYSLKSVDPWLMGQTALFLASKIEEFGLVSQKSIIQTCNSL 360
            + + N   +  C  W  DK    K+      +L G D   +      G  F F  G +LGL    +AT + YF RFY  +S K    ++ G   LFLA K+EE      K II+T  SL
Sbjct:   12 VTSANLDHTKPC--WYWDK----KDLAHTPSQLEGLDPATEARYRREGARFIFDVGTRLGLHYDTLATGIIYFHRFYMFHSFKQFPRYVTGACCLFLAGKVEETPKKC-KDIIKTARSL 123

HSP 2 Score: 50.447 bits (119), Expect = 2.730e-16
Identity = 33/93 (35.48%), Postives = 51/93 (54.84%), Query Frame = 3

Query:  408 QDVLDCEFILVEVLDCSLIVFHPYRSLLLYSENLSTSPNYQHDSSILQKAWKIVNDSLRTDLMLYYPPYLISLGCLFLACVMDKKNEEAIQSW 686
            ++V+  E IL++ +   L V HPY+ LL Y++ L    N      ++Q AW  VNDSL T L L + P +I++  ++LA  + K     IQ W
Sbjct:  138 EEVMVLERILLQTIKFDLQVEHPYQFLLKYAKQLKGDKN--KIQKLVQMAWTFVNDSLCTTLSLQWEPEIIAVAVMYLAGRLCKFE---IQEW 225

[Close]

BLAST of Cyclin-C vs. UniProt/SwissProt
Match: sp|Q3ZCK5|CCNC_BOVIN (Cyclin-C OS=Bos taurus OX=9913 GN=CCNC PE=2 SV=1)

HSP 1 Score: 148.673 bits (374), Expect = 1.712e-72
Identity = 69/151 (45.70%), Postives = 105/151 (69.54%), Query Frame = 3

Query:  357 FKQKFSQYFPREYPHKIQDVLDCEFILVEVLDCSLIVFHPYRSLLLYSENLSTSPNYQHDSSILQKAWKIVNDSLRTDLMLYYPPYLISLGCLFLACVMDKKNEEAIQSWFADLLVDFSKVMEVVKTMTGLYCLWKNCDDDKDIFNLLSKM 809
             K +FS  FP+E+P+K+  VL+CEF L+E++DC LIV+HPYR LL Y +++        +  +L  AW+IVND+ RTDL L YPP++I+L CL +ACV+ +K+    + WFA+L VD  K++E+++ +  LY  WKN D+ K++  +LSKM
Sbjct:  116 LKTRFSYAFPKEFPYKMNHVLECEFYLLELMDCCLIVYHPYRPLLQYVQDMG------QEDMLLPLAWRIVNDTYRTDLCLLYPPFMIALACLHVACVVQQKDA---RQWFAELSVDMEKILEIIRVILKLYEQWKNFDERKEMATILSKM 257

HSP 2 Score: 146.747 bits (369), Expect = 1.712e-72
Identity = 74/119 (62.18%), Postives = 88/119 (73.95%), Query Frame = 1

Query:   13 MAGNFWRSSHCLEWLLDKQYVLKNRESDIKELGGEDEYQKLMIFFTGVTFSFGEKLGLRQQVIATAVTYFKRFYAMYSLKSVDPWLMGQTALFLASKIEEFGLVSQKSIIQTCNSLNKN 369
            MAGNFW+SSH L+W+LDKQ +LK R+ D+K L  E+EY KL IFFT V  + GE L LRQQVIATA  YFKRFYA YSLKS+DP LM  T +FLASK+EEFG+VS   +I    S+ K 
Sbjct:    1 MAGNFWQSSHYLQWILDKQDLLKERQKDLKFLS-EEEYWKLQIFFTNVIQALGEHLKLRQQVIATATVYFKRFYARYSLKSIDPVLMAPTCVFLASKVEEFGVVSNTRLIAAATSVLKT 118

[Close]

BLAST of Cyclin-C vs. UniProt/SwissProt
Match: sp|P24863|CCNC_HUMAN (Cyclin-C OS=Homo sapiens OX=9606 GN=CCNC PE=1 SV=2)

HSP 1 Score: 147.517 bits (371), Expect = 4.231e-72
Identity = 67/151 (44.37%), Postives = 105/151 (69.54%), Query Frame = 3

Query:  357 FKQKFSQYFPREYPHKIQDVLDCEFILVEVLDCSLIVFHPYRSLLLYSENLSTSPNYQHDSSILQKAWKIVNDSLRTDLMLYYPPYLISLGCLFLACVMDKKNEEAIQSWFADLLVDFSKVMEVVKTMTGLYCLWKNCDDDKDIFNLLSKM 809
             K +FS  FP+E+P+++  +L+CEF L+E++DC LIV+HPYR LL Y +++        +  +L  AW+IVND+ RTDL L YPP++I+L CL +ACV+ +K+    + WFA+L VD  K++E+++ +  LY  WKN D+ K++  +LSKM
Sbjct:  116 LKTRFSYAFPKEFPYRMNHILECEFYLLELMDCCLIVYHPYRPLLQYVQDMG------QEDMLLPLAWRIVNDTYRTDLCLLYPPFMIALACLHVACVVQQKDA---RQWFAELSVDMEKILEIIRVILKLYEQWKNFDERKEMATILSKM 257

HSP 2 Score: 146.747 bits (369), Expect = 4.231e-72
Identity = 74/119 (62.18%), Postives = 88/119 (73.95%), Query Frame = 1

Query:   13 MAGNFWRSSHCLEWLLDKQYVLKNRESDIKELGGEDEYQKLMIFFTGVTFSFGEKLGLRQQVIATAVTYFKRFYAMYSLKSVDPWLMGQTALFLASKIEEFGLVSQKSIIQTCNSLNKN 369
            MAGNFW+SSH L+W+LDKQ +LK R+ D+K L  E+EY KL IFFT V  + GE L LRQQVIATA  YFKRFYA YSLKS+DP LM  T +FLASK+EEFG+VS   +I    S+ K 
Sbjct:    1 MAGNFWQSSHYLQWILDKQDLLKERQKDLKFLS-EEEYWKLQIFFTNVIQALGEHLKLRQQVIATATVYFKRFYARYSLKSIDPVLMAPTCVFLASKVEEFGVVSNTRLIAAATSVLKT 118

[Close]

BLAST of Cyclin-C vs. UniProt/SwissProt
Match: sp|P55168|CCNC_CHICK (Cyclin-C OS=Gallus gallus OX=9031 GN=CCNC PE=3 SV=1)

HSP 1 Score: 147.517 bits (371), Expect = 4.484e-72
Identity = 67/151 (44.37%), Postives = 105/151 (69.54%), Query Frame = 3

Query:  357 FKQKFSQYFPREYPHKIQDVLDCEFILVEVLDCSLIVFHPYRSLLLYSENLSTSPNYQHDSSILQKAWKIVNDSLRTDLMLYYPPYLISLGCLFLACVMDKKNEEAIQSWFADLLVDFSKVMEVVKTMTGLYCLWKNCDDDKDIFNLLSKM 809
             K +FS  FP+E+P+++  +L+CEF L+E++DC LIV+HPYR LL Y +++        +  +L  AW+IVND+ RTDL L YPP++I+L CL +ACV+ +K+    + WFA+L VD  K++E+++ +  LY  WKN D+ K++  +LSKM
Sbjct:  116 LKTRFSYAFPKEFPYRMNHILECEFYLLELMDCCLIVYHPYRPLLQYVQDMG------QEDMLLPLAWRIVNDTYRTDLCLLYPPFMIALACLHVACVVQQKDA---RQWFAELSVDMEKILEIIRVILKLYEQWKNFDERKEMATILSKM 257

HSP 2 Score: 146.747 bits (369), Expect = 4.484e-72
Identity = 74/119 (62.18%), Postives = 88/119 (73.95%), Query Frame = 1

Query:   13 MAGNFWRSSHCLEWLLDKQYVLKNRESDIKELGGEDEYQKLMIFFTGVTFSFGEKLGLRQQVIATAVTYFKRFYAMYSLKSVDPWLMGQTALFLASKIEEFGLVSQKSIIQTCNSLNKN 369
            MAGNFW+SSH L+W+LDKQ +LK R+ D+K L  E+EY KL IFFT V  + GE L LRQQVIATA  YFKRFYA YSLKS+DP LM  T +FLASK+EEFG+VS   +I    S+ K 
Sbjct:    1 MAGNFWQSSHYLQWILDKQDLLKERQKDLKFLS-EEEYWKLQIFFTNVIQALGEHLKLRQQVIATATVYFKRFYARYSLKSIDPVLMAPTCVFLASKVEEFGVVSNTRLISAATSVLKT 118

[Close]

BLAST of Cyclin-C vs. UniProt/SwissProt
Match: sp|Q4KLA0|CCNC_XENLA (Cyclin-C OS=Xenopus laevis OX=8355 GN=ccnc PE=2 SV=1)

HSP 1 Score: 147.132 bits (370), Expect = 4.636e-72
Identity = 67/151 (44.37%), Postives = 106/151 (70.20%), Query Frame = 3

Query:  357 FKQKFSQYFPREYPHKIQDVLDCEFILVEVLDCSLIVFHPYRSLLLYSENLSTSPNYQHDSSILQKAWKIVNDSLRTDLMLYYPPYLISLGCLFLACVMDKKNEEAIQSWFADLLVDFSKVMEVVKTMTGLYCLWKNCDDDKDIFNLLSKM 809
             K +FS  FP+E+P+++  +L+CEF L+E++DC LIV+HPYR LL Y +++        +  +L  AW+IVND+ RTDL L YPP++I+L CL +ACV+ +K+    + WFA+L VD  K++E+++ +  LY  WKN D+ K++ ++LSKM
Sbjct:  116 LKTRFSYAFPKEFPYRMNHILECEFYLLELMDCCLIVYHPYRPLLQYVQDMG------QEDMLLPLAWRIVNDTYRTDLCLLYPPFMIALACLHVACVVQQKDA---RQWFAELSVDMEKILEIIRVILKLYEQWKNFDERKEMASILSKM 257

HSP 2 Score: 146.747 bits (369), Expect = 4.636e-72
Identity = 74/119 (62.18%), Postives = 88/119 (73.95%), Query Frame = 1

Query:   13 MAGNFWRSSHCLEWLLDKQYVLKNRESDIKELGGEDEYQKLMIFFTGVTFSFGEKLGLRQQVIATAVTYFKRFYAMYSLKSVDPWLMGQTALFLASKIEEFGLVSQKSIIQTCNSLNKN 369
            MAGNFW+SSH L+W+LDKQ +LK R+ D+K L  E+EY KL IFFT V  + GE L LRQQVIATA  YFKRFYA YSLKS+DP LM  T +FLASK+EEFG+VS   +I    S+ K 
Sbjct:    1 MAGNFWQSSHYLQWILDKQDLLKERQKDLKFLS-EEEYWKLQIFFTNVIQALGEHLKLRQQVIATATVYFKRFYARYSLKSIDPVLMAPTCVFLASKVEEFGVVSNTRLISAATSVLKT 118

[Close]

BLAST of Cyclin-C vs. UniProt/SwissProt
Match: sp|Q62447|CCNC_MOUSE (Cyclin-C OS=Mus musculus OX=10090 GN=Ccnc PE=2 SV=4)

HSP 1 Score: 147.517 bits (371), Expect = 4.792e-72
Identity = 67/151 (44.37%), Postives = 105/151 (69.54%), Query Frame = 3

Query:  357 FKQKFSQYFPREYPHKIQDVLDCEFILVEVLDCSLIVFHPYRSLLLYSENLSTSPNYQHDSSILQKAWKIVNDSLRTDLMLYYPPYLISLGCLFLACVMDKKNEEAIQSWFADLLVDFSKVMEVVKTMTGLYCLWKNCDDDKDIFNLLSKM 809
             K +FS  FP+E+P+++  +L+CEF L+E++DC LIV+HPYR LL Y +++        +  +L  AW+IVND+ RTDL L YPP++I+L CL +ACV+ +K+    + WFA+L VD  K++E+++ +  LY  WKN D+ K++  +LSKM
Sbjct:  116 LKTRFSYAFPKEFPYRMNHILECEFYLLELMDCCLIVYHPYRPLLQYVQDMG------QEDVLLPLAWRIVNDTYRTDLCLLYPPFMIALACLHVACVVQQKDA---RQWFAELSVDMEKILEIIRVILKLYEQWKNFDERKEMATILSKM 257

HSP 2 Score: 146.362 bits (368), Expect = 4.792e-72
Identity = 74/119 (62.18%), Postives = 88/119 (73.95%), Query Frame = 1

Query:   13 MAGNFWRSSHCLEWLLDKQYVLKNRESDIKELGGEDEYQKLMIFFTGVTFSFGEKLGLRQQVIATAVTYFKRFYAMYSLKSVDPWLMGQTALFLASKIEEFGLVSQKSIIQTCNSLNKN 369
            MAGNFW+SSH L+W+LDKQ +LK R+ D+K L  E+EY KL IFFT V  + GE L LRQQVIATA  YFKRFYA YSLKS+DP LM  T +FLASK+EEFG+VS   +I    S+ K 
Sbjct:    1 MAGNFWQSSHYLQWILDKQDLLKERQKDLKFLS-EEEYWKLQIFFTNVIQALGEHLKLRQQVIATATVYFKRFYARYSLKSIDPVLMAPTCVFLASKVEEFGVVSNTRLIAATTSVLKT 118

[Close]

BLAST of Cyclin-C vs. TrEMBL
Match: D2DJV1 (CyclinC-like protein (Fragment) OS=Schmidtea mediterranea OX=79327 PE=2 SV=1)

HSP 1 Score: 261.536 bits (667), Expect = 4.997e-103
Identity = 131/161 (81.37%), Postives = 131/161 (81.37%), Query Frame = 3

Query:  360 KQKFSQYFPREYPHKIQDVLDCEFILVEVLDCSLIVFHPYRSLLLYSENLSTSPNYQHDSSILQKAWKIVNDSLRTDLMLYYPPYLISLGCLFLACVMDKKNEEAIQSWFADLLVDFSKVMEVVKTMTGLYCLWKNCDDDKDIFNLLSKMPKPKIHNANQQ 842
            KQKFSQYFPREYPHKIQDVLDCEFILVEVLDCSLIVFHPYRSLLLYSENLSTSPNYQHDS                              CLFLACVMDKKNEEAIQSWFADLLVDFSKVMEVVKTMTGLYCLWKNCDDDKDIFNLLSKMPKPKIHNANQQ
Sbjct:   90 KQKFSQYFPREYPHKIQDVLDCEFILVEVLDCSLIVFHPYRSLLLYSENLSTSPNYQHDSR-----------------------------CLFLACVMDKKNEEAIQSWFADLLVDFSKVMEVVKTMTGLYCLWKNCDDDKDIFNLLSKMPKPKIHNANQQ 221

HSP 2 Score: 143.28 bits (360), Expect = 4.997e-103
Identity = 71/76 (93.42%), Postives = 73/76 (96.05%), Query Frame = 1

Query:  136 MIFFTGVTFSFGEKLGLRQQVIATAVTYFKRFYAMYSLKSVDPWLMGQTALFLASKIEEFGLVSQKSIIQTCNSLN 363
            MIFFTGVTFSFGEKLGLRQQVIATAVTYFKRFYAMYS   VDPWLMGQTALFLASKIEEFGLVSQKSIIQTCNS++
Sbjct:    1 MIFFTGVTFSFGEKLGLRQQVIATAVTYFKRFYAMYS---VDPWLMGQTALFLASKIEEFGLVSQKSIIQTCNSVS 73

[Close]

BLAST of Cyclin-C vs. TrEMBL
Match: A0A0L8IHF8 (Uncharacterized protein OS=Octopus bimaculoides OX=37653 GN=OCBIM_22004206mg PE=3 SV=1)

HSP 1 Score: 158.688 bits (400), Expect = 4.767e-74
Identity = 76/154 (49.35%), Postives = 106/154 (68.83%), Query Frame = 3

Query:  360 KQKFSQYFPREYPHKIQDVLDCEFILVEVLDCSLIVFHPYRSLLLYSENLSTSPNYQHDSSILQKAWKIVNDSLRTDLMLYYPPYLISLGCLFLACVMDKKNEEAIQSWFADLLVDFSKVMEVVKTMTGLYCLWKNCDDDKDIFNLLSKMPKPK 821
            K KFS  + +EYP++I  VL+CEF L+E++DC L+++HPYR L+ Y  +L        D ++L  AW+IVNDSLRTD+ L YPPYLI+L CL +ACV+  K+    + WFA+L VD  KV+E+ K +   Y LWKN ++ K+I  +L KMPKPK
Sbjct:  117 KTKFSHAYTQEYPYRINSVLECEFYLLEMMDCCLVLYHPYRPLIQYCADLG------QDDNLLPVAWRIVNDSLRTDVCLMYPPYLIALACLHIACVIQDKDG---RQWFAELSVDMDKVLEITKQILAFYELWKNYEEKKEIIAVLVKMPKPK 261

HSP 2 Score: 149.828 bits (377), Expect = 4.767e-74
Identity = 66/119 (55.46%), Postives = 92/119 (77.31%), Query Frame = 1

Query:   13 MAGNFWRSSHCLEWLLDKQYVLKNRESDIKELGGEDEYQKLMIFFTGVTFSFGEKLGLRQQVIATAVTYFKRFYAMYSLKSVDPWLMGQTALFLASKIEEFGLVSQKSIIQTCNSLNKN 369
            MAGNFW+SSH  +WLLD+Q +L+ R++D+K L  EDEYQK+M+F++    + GE+L +RQQVIA+A  YFKRFYA  SL+S+DPWLM  T +FLASK+EEFG++S   ++ TC ++ K 
Sbjct:    1 MAGNFWQSSHYQQWLLDRQDILRERQADLKVLS-EDEYQKIMVFYSNFIQALGEQLKMRQQVIASATVYFKRFYARNSLRSIDPWLMAPTCIFLASKVEEFGVISNNKLMTTCQNVVKT 118

[Close]

BLAST of Cyclin-C vs. TrEMBL
Match: T1IVG7 (Uncharacterized protein OS=Strigamia maritima OX=126957 PE=3 SV=1)

HSP 1 Score: 163.696 bits (413), Expect = 1.768e-73
Identity = 80/178 (44.94%), Postives = 116/178 (65.17%), Query Frame = 3

Query:  360 KQKFSQYFPREYPHKIQDVLDCEFILVEVLDCSLIVFHPYRSLLLYSENLSTSPNYQHDSSILQKAWKIVNDSLRTDLMLYYPPYLISLGCLFLACVMDKKNEEAIQSWFADLLVDFSKVMEVVKTMTGLYCLWKNCDDDKDIFNLLSKMPKPKIHNANQQHNISHQQVSNNNVMKSN 893
            K KF+    +EYP++IQ+V++CEF L+E++DC L+++ PYR L+ Y+++L       H+ +IL  AW+IVNDSLRTD+ L YPPYLISL CL +ACV+ +K+   ++ WFA+L VD  K++E+ + +  LY LWK  D+ K+I  LL+KMPK K              V  NN   SN
Sbjct:  117 KTKFNYAHSQEYPYRIQNVVECEFFLLEMMDCCLVIYLPYRPLIQYAQDLG------HEDTILPLAWRIVNDSLRTDVCLLYPPYLISLACLHMACVIQQKD---VKQWFAELNVDMEKILEITRYILALYELWKGFDERKEIQALLAKMPKAKTQPPGLNTGGPQNNVDPNNPQSSN 285

HSP 2 Score: 142.51 bits (358), Expect = 1.768e-73
Identity = 67/122 (54.92%), Postives = 90/122 (73.77%), Query Frame = 1

Query:   13 MAGNFWRSSHCLEWLLDKQYVLKNRESDIKELGGEDEYQKLMIFFTGVTFSFGEKLGLRQQVIATAVTYFKRFYAMYSLKSVDPWLMGQTALFLASKIEEFGLVSQKSIIQTCNSLNKNSPN 378
            MAGNFW SSH  +WLLDKQ +++ R+ D+  L  E+EYQK++IFF  +  + GE+L +RQQVIATA TYFKRFYA  SLK +DP+L+  T +FLASK+EEFG++S   +I TC ++ K   N
Sbjct:    1 MAGNFWHSSHYQQWLLDKQDLIRERQVDMAVLT-EEEYQKIIIFFANLIQTLGEQLKVRQQVIATATTYFKRFYARNSLKCIDPFLLAPTCIFLASKVEEFGMISNSRLISTCQTVIKTKFN 121

[Close]

BLAST of Cyclin-C vs. TrEMBL
Match: V4B3J3 (Uncharacterized protein OS=Lottia gigantea OX=225164 GN=LOTGIDRAFT_211728 PE=3 SV=1)

HSP 1 Score: 155.221 bits (391), Expect = 1.705e-72
Identity = 71/156 (45.51%), Postives = 111/156 (71.15%), Query Frame = 3

Query:  360 KQKFSQYFPREYPHKIQDVLDCEFILVEVLDCSLIVFHPYRSLLLYSENLSTSPNYQHDSSILQKAWKIVNDSLRTDLMLYYPPYLISLGCLFLACVMDKKNEEAIQSWFADLLVDFSKVMEVVKTMTGLYCLWKNCDDDKDIFNLLSKMPKPKIH 827
            K KF   F  +YP++IQ+VL+CEF L+E++DC LI++ PYR L  Y  +L      + ++ +LQ +W+IVNDSLRTD+ L YPPYLI++ CL +ACV+ +K+   ++ WFA+L VD  K++E+ + +  LY +WK  D+ K+I  +L+K+PKPK++
Sbjct:  117 KTKFPHAFNGDYPYRIQNVLECEFYLLEMMDCCLILYQPYRPLTQYCNDL------KPETDLLQVSWRIVNDSLRTDIPLLYPPYLIAIACLHMACVIKQKD---VKQWFAELSVDMDKILEISRQILALYEMWKTYDEKKEIAGILAKIPKPKLN 263

HSP 2 Score: 147.902 bits (372), Expect = 1.705e-72
Identity = 67/119 (56.30%), Postives = 89/119 (74.79%), Query Frame = 1

Query:   13 MAGNFWRSSHCLEWLLDKQYVLKNRESDIKELGGEDEYQKLMIFFTGVTFSFGEKLGLRQQVIATAVTYFKRFYAMYSLKSVDPWLMGQTALFLASKIEEFGLVSQKSIIQTCNSLNKN 369
            MAGNFW SSH  +W+LDKQ +++ R++D+K +  EDEY K+MIFF     + GE+L +RQQVIATA  YFKRFYA  SLK +DPWLM  T++FLASK+EEFG++S   +I TC ++ K 
Sbjct:    1 MAGNFWHSSHYQQWVLDKQDLMRERQADLK-VVSEDEYSKVMIFFANFIQALGEQLKVRQQVIATATVYFKRFYARNSLKCIDPWLMAPTSIFLASKVEEFGVISNSRLISTCQTVVKT 118

[Close]

BLAST of Cyclin-C vs. TrEMBL
Match: A0A4W5KWB1 (Cyclin C OS=Hucho hucho OX=62062 PE=3 SV=1)

HSP 1 Score: 157.532 bits (397), Expect = 4.111e-72
Identity = 75/178 (42.13%), Postives = 120/178 (67.42%), Query Frame = 3

Query:  357 FKQKFSQYFPREYPHKIQDVLDCEFILVEVLDCSLIVFHPYRSLLLYSENLSTSPNYQHDSSILQKAWKIVNDSLRTDLMLYYPPYLISLGCLFLACVMDKKNEEAIQSWFADLLVDFSKVMEVVKTMTGLYCLWKNCDDDKDIFNLLSKMPKPKIHNANQQHNISHQQVSNNNVMKS 890
             K +FS  FP+E+P+++  +L+CEF L+E++DC LIV+HPYR LL Y +++        +  +L  AW+IVND+ RTDL L YPP++I+L CL +ACV+ +K+    + WFA+L VD  K++E+++ +  LY  WKN DD K++  +L+KMPKP+    N +++ S     NN+ ++S
Sbjct:  116 LKTRFSYAFPKEFPYRMNHILECEFYLLELMDCCLIVYHPYRPLLQYVQDMG------QEDMLLPLAWRIVNDTYRTDLCLLYPPFMIALACLHVACVVQQKDA---RQWFAELSVDMEKILEIIRVILKLYDQWKNFDDRKEMAAVLNKMPKPR-PPPNSENDQSSSGNQNNSYIQS 283

HSP 2 Score: 144.436 bits (363), Expect = 4.111e-72
Identity = 72/118 (61.02%), Postives = 86/118 (72.88%), Query Frame = 1

Query:   13 MAGNFWRSSHCLEWLLDKQYVLKNRESDIKELGGEDEYQKLMIFFTGVTFSFGEKLGLRQQVIATAVTYFKRFYAMYSLKSVDPWLMGQTALFLASKIEEFGLVSQKSIIQTCNSLNK 366
            MAGNFW+SSH L+W+LDKQ ++K R+ DIK +  ED Y KL IFF  V  + GE L LRQQVIATA  YFKRFYA YSLKS+DP LM  T +FLASK+EEFG+VS   +I    S+ K
Sbjct:    1 MAGNFWQSSHYLQWVLDKQDLMKERQKDIKFMSEED-YWKLQIFFANVIQALGEHLKLRQQVIATATVYFKRFYARYSLKSIDPVLMAPTCVFLASKVEEFGVVSNTRLISAATSVLK 117

[Close]

BLAST of Cyclin-C vs. Ensembl Cavefish
Match: ccnk (cyclin K [Source:NCBI gene;Acc:103046138])

HSP 1 Score: 52.373 bits (124), Expect = 7.829e-16
Identity = 28/67 (41.79%), Postives = 36/67 (53.73%), Query Frame = 1

Query:  160 FSFGEKLGLRQQVIATAVTYFKRFYAMYSLKSVDPWLMGQTALFLASKIEEFGLVSQKSIIQTCNSL 360
            F  G +LGL    +AT + YF RFY  +S K    ++ G   LFLA K+EE      K II+T  SL
Sbjct:   58 FDVGTRLGLHYDTLATGIIYFHRFYMFHSFKQFPRYVTGACCLFLAGKVEETPKKC-KDIIKTARSL 123

HSP 2 Score: 50.0618 bits (118), Expect = 7.829e-16
Identity = 33/93 (35.48%), Postives = 52/93 (55.91%), Query Frame = 3

Query:  408 QDVLDCEFILVEVLDCSLIVFHPYRSLLLYSENLSTSPNYQHDSSILQKAWKIVNDSLRTDLMLYYPPYLISLGCLFLACVMDKKNEEAIQSW 686
            ++V+  E IL++ +   L V HPY+ LL Y++ L    N      ++Q AW  VNDSL T L L + P +I++  ++LA  + K +   IQ W
Sbjct:  138 EEVMVLERILLQTIKFDLQVEHPYQFLLRYAKQLKGDKNKVQ--KLVQMAWTFVNDSLCTMLSLQWEPEIIAIAVMYLAGRLCKFD---IQEW 225

[Close]

BLAST of Cyclin-C vs. Ensembl Cavefish
Match: ccnq (cyclin Q [Source:NCBI gene;Acc:103022361])

HSP 1 Score: 46.2098 bits (108), Expect = 3.278e-7
Identity = 21/62 (33.87%), Postives = 38/62 (61.29%), Query Frame = 1

Query:  169 GEKLGLRQQVIATAVTYFKRFYAMYSLKSVDPWLMGQTALFLASKIEEFGLVSQKSIIQTCN 354
            G KLG+R   +ATA + + +F+   +L   +P+L+  + ++LA K+EE  L + + II  C+
Sbjct:   45 GVKLGMRSVPVATACSLYHKFFQSATLDVYEPYLVAMSCIYLAGKVEEQHLRT-RDIINVCH 105

HSP 2 Score: 26.9498 bits (58), Expect = 3.278e-7
Identity = 16/69 (23.19%), Postives = 33/69 (47.83%), Query Frame = 3

Query:  411 DVLDCEFILVEVLDCSLIVFHPYRSLLLYSENLSTSPNYQ--HDSSILQKAWKIVNDSLRTDLMLYYPP 611
             V+ CE +++  L+  +   HP++ LL Y  ++    N      + I + AW ++ DS    + + + P
Sbjct:  127 SVVQCELLILRQLNFQVSFEHPHKYLLHYLLSVRNLLNRHAWSRTPIAETAWALLKDSYHGPVCVRHRP 195

[Close]

BLAST of Cyclin-C vs. Ensembl Cavefish
Match: ccnt2b (cyclin-T2-like [Source:NCBI gene;Acc:103028284])

HSP 1 Score: 41.5874 bits (96), Expect = 5.544e-7
Identity = 19/49 (38.78%), Postives = 28/49 (57.14%), Query Frame = 1

Query:  166 FGEKLGLRQQVIATAVTYFKRFYAMYSLKSVDPWLMGQTALFLASKIEE 312
             G++L + Q  I TA+ Y  RFY + S       ++  T LFLA+K+EE
Sbjct:   62 MGQRLNVSQLTINTAIVYMHRFYMLNSFTKFHRNIISPTTLFLAAKVEE 110

HSP 2 Score: 31.187 bits (69), Expect = 5.544e-7
Identity = 20/86 (23.26%), Postives = 44/86 (51.16%), Query Frame = 3

Query:  393 YPHKIQDVLDCEFILVEVLDCSLIVFHPYRSLLLYSENLSTSPNYQHDSSILQKAWKIVNDSLR-TDLMLYYPPYLISLGCLFLAC 647
            Y  + Q+++  E I+++ L   + + HP+  ++  S+ +  S +      + Q ++ +  +SL  T   L Y P +++  C+ LAC
Sbjct:  140 YLQQAQELVLLETIVLQTLGFEITIEHPHTDVVRCSQLVRASKD------LAQTSYFMATNSLHLTTFCLQYKPTVVACVCIHLAC 219

[Close]

BLAST of Cyclin-C vs. Ensembl Cavefish
Match: ccnt2a (cyclin T2 [Source:NCBI gene;Acc:103023729])

HSP 1 Score: 41.5874 bits (96), Expect = 8.537e-7
Identity = 19/49 (38.78%), Postives = 28/49 (57.14%), Query Frame = 1

Query:  166 FGEKLGLRQQVIATAVTYFKRFYAMYSLKSVDPWLMGQTALFLASKIEE 312
             G++L + Q  I TA+ Y  RFY  +S       ++  T LFLA+K+EE
Sbjct:   47 MGQRLNVSQLTINTAIVYMHRFYMYHSFTKFHRNIISPTTLFLAAKVEE 95

HSP 2 Score: 30.0314 bits (66), Expect = 8.537e-7
Identity = 28/121 (23.14%), Postives = 58/121 (47.93%), Query Frame = 3

Query:  393 YPHKIQDVLDCEFILVEVLDCSLIVFHPYRSLLLYSENLSTSPNYQHDSSILQKAWKIVNDSLR-TDLMLYYPPYLISLGCLFLACVMDKKN---EEAIQSWFADLLVDFSKVMEVVKTMT 743
            Y  + Q+++  E I+++ L   + + HP+  ++  S+ +  S +      + Q ++ +  +SL  T   L Y P +I+  C+ L C   K+        +SW+    VD S  +E++  +T
Sbjct:  125 YLQQAQELVILETIVLQTLGFEITIEHPHTDVVKCSQLVRASKD------LAQTSYFMATNSLHLTTFCLQYKPTVIACVCIHLVCKWSKREIPLSTDGKSWWE--YVDNSVTIELLDELT 237

[Close]

BLAST of Cyclin-C vs. Ensembl Cavefish
Match: ccnt2b (cyclin-T2-like [Source:NCBI gene;Acc:103028284])

HSP 1 Score: 41.5874 bits (96), Expect = 9.758e-7
Identity = 19/49 (38.78%), Postives = 28/49 (57.14%), Query Frame = 1

Query:  166 FGEKLGLRQQVIATAVTYFKRFYAMYSLKSVDPWLMGQTALFLASKIEE 312
             G++L + Q  I TA+ Y  RFY + S       ++  T LFLA+K+EE
Sbjct:   58 MGQRLNVSQLTINTAIVYMHRFYMLNSFTKFHRNIISPTTLFLAAKVEE 106

HSP 2 Score: 30.0314 bits (66), Expect = 9.758e-7
Identity = 19/86 (22.09%), Postives = 43/86 (50.00%), Query Frame = 3

Query:  393 YPHKIQDVLDCEFILVEVLDCSLIVFHPYRSLLLYSENLSTSPNYQHDSSILQKAWKIVNDSLR-TDLMLYYPPYLISLGCLFLAC 647
            Y  + Q+++  E I+++ L   + + HP+  ++  S+ +     +     + Q ++ +  +SL  T   L Y P +++  C+ LAC
Sbjct:  136 YLQQAQELVLLETIVLQTLGFEITIEHPHTDVVRCSQLVRGRCFHLSSKDLAQTSYFMATNSLHLTTFCLQYKPTVVACVCIHLAC 221

[Close]

BLAST of Cyclin-C vs. Ensembl Sea Lamprey
Match: ccnc (cyclin C [Source:ZFIN;Acc:ZDB-GENE-030131-7369])

HSP 1 Score: 139.043 bits (349), Expect = 1.318e-63
Identity = 68/160 (42.50%), Postives = 105/160 (65.62%), Query Frame = 3

Query:  357 FKQKFSQYFPREYPHKIQDVLDCEFILVEVLDCSLIVFHPYRSLLLYSENLSTSPNYQHDSSILQKAWKIVNDSLRTDLMLYYPPYLISLGCLFLACVMDKKN------EEAIQS---WFADLLVDFSKVMEVVKTMTGLYCLWKNCDDDKDIFNLLSKM 809
            FK KFS  F +++P ++  VL+CEF L+E++DC LIV+HPYR+L  Y  ++        D  +LQ AWKIVND+ RTDL L YPP++I+L  L +AC + +K       +E ++    WFA+L VD  K++E+ + +  LY +W++ D+ K+I ++LSKM
Sbjct:  104 FKNKFSYAFSKDFPFRVNHVLECEFYLLELMDCCLIVYHPYRALTQYVHDMGP------DEQLLQIAWKIVNDTYRTDLCLMYPPFMIALASLHMACAIQQKEPPKEHQKEVLRDGRHWFAELSVDMDKILEITRAILKLYEVWQSYDEKKEIASILSKM 257

HSP 2 Score: 121.324 bits (303), Expect = 1.318e-63
Identity = 58/107 (54.21%), Postives = 78/107 (72.90%), Query Frame = 1

Query:   49 EWLLDKQYVLKNRESDIKELGGEDEYQKLMIFFTGVTFSFGEKLGLRQQVIATAVTYFKRFYAMYSLKSVDPWLMGQTALFLASKIEEFGLVSQKSIIQTCNSLNKN 369
            +W+LDKQ ++K R+ D+K L  E+EY K+ IFF  V  + GE+L LRQQVIATA  YFKRFYA YSL+ +DP LM  T +FLASK+EEFG++S   +I   +++ KN
Sbjct:    1 QWILDKQDIMKERQKDLKNLT-EEEYWKIHIFFANVIQALGEQLKLRQQVIATATVYFKRFYARYSLQCIDPVLMAPTCVFLASKVEEFGVISNSRLITAASTVFKN 106

[Close]

BLAST of Cyclin-C vs. Ensembl Sea Lamprey
Match: ENSPMAT00000003409.1 (pep scaffold:Pmarinus_7.0:GL483875:8555:11659:-1 gene:ENSPMAG00000003120.1 transcript:ENSPMAT00000003409.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 47.7506 bits (112), Expect = 6.889e-14
Identity = 35/98 (35.71%), Postives = 51/98 (52.04%), Query Frame = 3

Query:  405 IQDVLDCEFILVEVLDCSLIVFHPYRSLLLYSENLSTSPNYQHDSSILQK----AWKIVNDSLRTDLMLYYPPYLISLGCLFLACVMDKKNEEAIQSW 686
            +++V+  E IL++ +   L + HPY  LL Y++ L        D S LQK    AW  VNDSL T L L + P +I +  ++LA  + K     IQ W
Sbjct:  120 LEEVMVLERILLQTIKFDLQLEHPYHFLLKYAKQLKAG-----DKSKLQKLVQMAWTFVNDSLCTMLCLQWEPEIIGVAVMYLAGRLCKFE---IQEW 209

HSP 2 Score: 45.8246 bits (107), Expect = 6.889e-14
Identity = 28/71 (39.44%), Postives = 36/71 (50.70%), Query Frame = 1

Query:  160 FSFGEKLGL----RQQVIATAVTYFKRFYAMYSLKSVDPWLMGQTALFLASKIEEFGLVSQKSIIQTCNSL 360
            F  G +LGL        +AT + YF RFY  +S K    ++ G   LFLA K+EE      K II+T  SL
Sbjct:   38 FDVGTRLGLYPLSHYDTLATGMVYFHRFYMFHSFKQFPRYVTGACCLFLAGKVEETP-KKCKDIIKTARSL 107

[Close]

BLAST of Cyclin-C vs. Ensembl Sea Lamprey
Match: ENSPMAT00000003411.1 (pep scaffold:Pmarinus_7.0:GL483875:8648:11677:-1 gene:ENSPMAG00000003120.1 transcript:ENSPMAT00000003411.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 46.595 bits (109), Expect = 1.106e-13
Identity = 28/71 (39.44%), Postives = 36/71 (50.70%), Query Frame = 1

Query:  160 FSFGEKLGLRQQ----VIATAVTYFKRFYAMYSLKSVDPWLMGQTALFLASKIEEFGLVSQKSIIQTCNSL 360
            F  G +LGL        +AT + YF RFY  +S K    ++ G   LFLA K+EE      K II+T  SL
Sbjct:   44 FDVGTRLGLLHDRHYDTLATGMVYFHRFYMFHSFKQFPRYVTGACCLFLAGKVEETP-KKCKDIIKTARSL 113

HSP 2 Score: 46.595 bits (109), Expect = 1.106e-13
Identity = 32/85 (37.65%), Postives = 47/85 (55.29%), Query Frame = 3

Query:  402 KIQDVLDCEFILVEVLDCSLIVFHPYRSLLLYSENLSTSPNYQHDSSILQK----AWKIVNDSLRTDLMLYYPPYLISLGCLFLA 644
            K ++V+  E IL++ +   L + HPY  LL Y++ L      + D S LQK    AW  VNDSL T L L + P +I +  ++LA
Sbjct:  127 KQEEVMVLERILLQTIKFDLQLEHPYHFLLKYAKQL------KGDKSKLQKLVQMAWTFVNDSLCTMLCLQWEPEIIGVAVMYLA 205

[Close]

BLAST of Cyclin-C vs. Ensembl Sea Lamprey
Match: ccnq (cyclin Q [Source:NCBI gene;Acc:553650])

HSP 1 Score: 44.669 bits (104), Expect = 2.360e-8
Identity = 29/90 (32.22%), Postives = 47/90 (52.22%), Query Frame = 1

Query:  169 GEKLGLRQQVIATAVTYFKRFYAMYSLKSVDPWLMGQTALFLASKIEEFGLVSQKSIIQTCNSLNKNSPNISPENILIKF-KMYWTVNLS 435
            G KLG+R   +ATA T +  F++  SL   DP L+  + L+LA K EE   V  + II   +       +++P+  L++  K +W +  S
Sbjct:   21 GVKLGMRSVPLATACTLYHAFFSEVSLDDYDPHLVAASCLYLAGKAEE-QHVRLRDIINVVHR------HLNPDKELLQLSKEFWELRDS 103

HSP 2 Score: 30.0314 bits (66), Expect = 2.360e-8
Identity = 17/68 (25.00%), Postives = 36/68 (52.94%), Query Frame = 3

Query:  414 VLDCEFILVEVLDCSLIVFHPYRSLLLYSENLS---TSPNYQHDSSILQKAWKIVNDS-LRTDLMLYY 605
            ++ CE +++ VL   +   HP++ LL Y  +L     +  ++    + + AW +++DS LR   +L +
Sbjct:  104 LVQCELLILRVLKFQISFTHPHKYLLYYLTSLRNWMGTWAWERAGPLAETAWALLSDSYLRGGAILRH 171

[Close]

BLAST of Cyclin-C vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007549.1 (pep scaffold:Pmarinus_7.0:GL483420:1071:10573:1 gene:ENSPMAG00000006818.1 transcript:ENSPMAT00000007549.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 45.0542 bits (105), Expect = 1.277e-7
Identity = 20/45 (44.44%), Postives = 29/45 (64.44%), Query Frame = 1

Query:  178 LGLRQQVIATAVTYFKRFYAMYSLKSVDPWLMGQTALFLASKIEE 312
            L   Q VI TA+ Y  RF+  +S K V   L+ Q+A+FLA+K+E+
Sbjct:    1 LNRPQLVINTAIVYMHRFFMFHSFKDVHKHLLAQSAIFLAAKVED 45

HSP 2 Score: 27.335 bits (59), Expect = 1.277e-7
Identity = 17/61 (27.87%), Postives = 29/61 (47.54%), Query Frame = 3

Query:  384 PREYP---------HKIQDVLDCEFILVEVLDCSLIVFHPYRSLLLYSENLSTSPNYQHDS 539
            PRE P          K QD++  E +L++ L   + V HP+  ++  S+ +  S +  H S
Sbjct:   63 PREAPLNPKHLVYLQKAQDLIMLETMLLQTLGFDVTVVHPHTHVVKCSQLVRASKDLAHTS 123

[Close]

BLAST of Cyclin-C vs. Ensembl Yeast
Match: SSN8 (Cyclin-like component of the RNA polymerase II holoenzyme; involved in phosphorylation of the RNA polymerase II C-terminal domain; forms a kinase-cyclin pair in the RNAPII holoenzyme with Ssn3p; required for both entry into and execution of the meiotic program; involved in glucose repression and telomere maintenance; cyclin homolog 35% identical to human cyclin C [Source:SGD;Acc:S000004970])

HSP 1 Score: 65.4698 bits (158), Expect = 6.337e-19
Identity = 47/152 (30.92%), Postives = 68/152 (44.74%), Query Frame = 3

Query:  381 FPREYPHKIQDVLDCEFILVEVLDCSLIVFHPYRSLLLYSENLSTSP-NYQHDSSILQKAWKIVNDSLRTDLMLYYPPYLISLGCLFLAC-------------------VMDKKNEE-----AIQSWFADLLVDFSKVMEVVKTMTGLYCLW 761
            +P   P     V + EF L+E L+  LIV HPY+SL    + L   P      S  LQ  W ++NDS   D+ L YPP++I++ CLF+                     + D KN       A   + A+ LVD  +VM+ ++    LY  W
Sbjct:  149 WPEFIPPDPTKVTEFEFYLLEELESYLIVHHPYQSLKQIVQVLKQPPFQITLSSDDLQNCWSLINDSYINDVHLLYPPHIIAVACLFITISIHGKPTKGSSLASAASEAIRDPKNSSSPVQIAFNRFMAESLVDLEEVMDTIQEQITLYDHW 300

HSP 2 Score: 44.669 bits (104), Expect = 6.337e-19
Identity = 33/133 (24.81%), Postives = 55/133 (41.35%), Query Frame = 1

Query:   13 MAGNFWRSSHCLEWLLDKQYVLKNRES-----------------DIKELGGE----------------DEYQKLMIFFTGVTFSFGEKLGLRQQVIATAVTYFKRFYAMYSLKSVDPWLMGQTALFLASKIEE 312
            M+G+FW S+    W   K  + K R+                  D K+ G E                D+   L I+   +    G +L +RQ  +ATA  Y  RF    S++ ++ +++  T ++LA K+EE
Sbjct:    1 MSGSFWTSTQRHHWQYTKASLAKERQKLWLLECQLFPQGLNIVMDSKQNGIEQSITKNIPITHRDLHYDKDYNLRIYCYFLIMKLGRRLNIRQYALATAHIYLSRFLIKASVREINLYMLVTTCVYLACKVEE 133

[Close]

BLAST of Cyclin-C vs. Ensembl Yeast
Match: CCL1 (Cyclin associated with protein kinase Kin28p; Kin28p is the TFIIH-associated carboxy-terminal domain (CTD) kinase involved in transcription initiation at RNA polymerase II promoters; human homolog CCNH allows growth of yeast ccl1 temperature-sensitive mutant at restrictive temperature [Source:SGD;Acc:S000006229])

HSP 1 Score: 45.0542 bits (105), Expect = 1.262e-9
Identity = 24/75 (32.00%), Postives = 40/75 (53.33%), Query Frame = 1

Query:  133 LMIFFTGVTFSFGEKLGLRQQVIATAVTYFKRFYAMYSLKSVDPWLMGQTALFLASKIEEFGLVSQKSIIQTCNS 357
            L+ F+        + L L  +V+ATA+++F+RF+   S+  +DP  +  T +FLA K E +  +S  S  Q   S
Sbjct:  116 LVNFYAKKVQVIAQHLNLPTEVVATAISFFRRFFLENSVMQIDPKSIVHTTIFLACKSENY-FISVDSFAQKAKS 189

HSP 2 Score: 33.4982 bits (75), Expect = 1.262e-9
Identity = 27/85 (31.76%), Postives = 40/85 (47.06%), Query Frame = 3

Query:  414 VLDCEFILVEVLDCSLIVFHPYRSL---------LLYSENLSTSPNYQHDSSILQKAWKIVNDSLRTDLMLYYPPYLISLGCLFL 641
            VL  EF L+E L  SL+  HPY+ L         +LY +      NY     I  +  K +  +L TD++ +Y P  I+L  L +
Sbjct:  194 VLKFEFKLLESLKFSLLNHHPYKPLHGFFLDIQNVLYGK---VDLNYM--GQIYDRCKKRITAALLTDVVYFYTPPQITLATLLI 273

[Close]

BLAST of Cyclin-C vs. Ensembl Nematostella
Match: EDO32917 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7STP9])

HSP 1 Score: 142.51 bits (358), Expect = 7.071e-65
Identity = 68/160 (42.50%), Postives = 107/160 (66.88%), Query Frame = 3

Query:  360 KQKFSQYFPRE-YPHKIQDVLDCEFILVEVLDCSLIVFHPYRSLLLYSENLSTSPNYQHDSSILQKAWKIVNDSLRTDLMLYYPPYLISLGCLFLACVMDKKNEEAIQSWFADLLVDFSKVMEVVKTMTGLYCLWKNCDDDKDIFNLLSKMPKPKIHNAN 836
            K K+S  F  E +P+++  VL+CEF L+E+LDC LI++HPYR L  Y  +L        + +IL  AW+I+NDSLRTD+ L YPPYLI+L  + +ACV+ +K+    + WFA+L VD  +++E+   +  LY +WKN ++ ++I  +L+K PKPK+  ++
Sbjct:  117 KNKYSYAFQMEQFPYRMNQVLECEFYLLEMLDCCLIIYHPYRPLTQYVSDLGM------EEAILPTAWRIINDSLRTDIFLIYPPYLIALAAIHMACVIQQKDS---KQWFAELSVDMDQIVEITHHILRLYEIWKNFEEKQEIRGILNKAPKPKVRPSS 267

HSP 2 Score: 123.25 bits (308), Expect = 7.071e-65
Identity = 60/119 (50.42%), Postives = 81/119 (68.07%), Query Frame = 1

Query:   13 MAGNFWRSSHCLEWLLDKQYVLKNRESDIKELGGEDEYQKLMIFFTGVTFSFGEKLGLRQQVIATAVTYFKRFYAMYSLKSVDPWLMGQTALFLASKIEEFGLVSQKSIIQTCNSLNKN 369
            MA NFW SSHC +W+LD   ++  R+ D++ L  E EYQK+ IF++    S GE L LRQQVIATA  +FKRFY+  SLKS+DP L+  T ++LASK+EE G +S   +I   +S+ KN
Sbjct:    1 MAANFWLSSHCNQWMLDVDEIMIGRQQDLQFLT-EVEYQKVHIFYSNFMQSLGEHLDLRQQVIATATVFFKRFYSKNSLKSIDPLLIAPTCVYLASKVEECGAISNNKLISASSSVVKN 118

[Close]

BLAST of Cyclin-C vs. Ensembl Nematostella
Match: EDO45644 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RSI9])

HSP 1 Score: 49.2914 bits (116), Expect = 1.168e-14
Identity = 26/72 (36.11%), Postives = 41/72 (56.94%), Query Frame = 1

Query:  169 GEKLGLRQQVIATAVTYFKRFYAMYSLKSVDPWLMGQTALFLASKIEEFGLVSQKSIIQTC-NSLNKNSPNI 381
            G KL L Q  +++A   + +F+     K  DP+L+G TA++LASK EE      + +I  C  S +K+SP +
Sbjct:   28 GAKLSLPQNAMSSACVLYHQFWKGCDPKDFDPYLIGMTAIYLASKAEECP-CKVRDVINVCYRSSHKDSPCL 98

HSP 2 Score: 47.7506 bits (112), Expect = 1.168e-14
Identity = 33/117 (28.21%), Postives = 63/117 (53.85%), Query Frame = 3

Query:  408 QDVLDCEFILVEVLDCSLIVFHPYRSLLLYSENLS--TSPNYQHDSSILQKAWKIVNDSLRTDLMLYYPPYLISLGCLFLA--CV-MDKKNEEAIQSWFADLLVDFSKVMEVVKTMT 743
            + V++CE +++ VL   +   +P++ LL Y + L   T P     S + Q +W  + DS    L L YPP  +++  L  A  CV ++  ++EA++ W+  L  D +   E+++++T
Sbjct:  109 ESVVNCELLMLRVLGFRVSYDNPHKYLLHYLKVLQDWTCPGMWERSQVPQISWSYLLDSHHIPLCLEYPPAHVAVALLHFAVECVGLEVPSQEAVRPWWKALCSDVTP--ELIQSIT 223

[Close]

BLAST of Cyclin-C vs. Ensembl Nematostella
Match: EDO48578 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RIW0])

HSP 1 Score: 56.9954 bits (136), Expect = 3.765e-12
Identity = 29/64 (45.31%), Postives = 37/64 (57.81%), Query Frame = 1

Query:  169 GEKLGLRQQVIATAVTYFKRFYAMYSLKSVDPWLMGQTALFLASKIEEFGLVSQKSIIQTCNSL 360
            G K+GLR   +AT   YF RFY + S K+   W+ G   LFLA K+EE      + II+T NSL
Sbjct:   41 GNKMGLRYDTMATGAVYFHRFYMIQSFKNFPRWVTGAACLFLAGKVEETP-KKCRDIIKTANSL 103

HSP 2 Score: 31.5722 bits (70), Expect = 3.765e-12
Identity = 27/87 (31.03%), Postives = 44/87 (50.57%), Query Frame = 3

Query:  396 PHKIQDVLDCEFILVEVLDCSLIVFHPYRSLLLYSENLSTSPNYQHDSSILQKAWKIVNDSLRTDLMLYYPPYLISLGCLFLACVMD 656
            P   ++V+  E IL++ +   L V HPY  LL   + L    +    + ++Q AW  +NDSL T L L +   +I+   L LA  ++
Sbjct:  114 PDPKEEVMIYERILLQTIKFDLQVEHPYPCLLKLGKGLKG--DRAKLNKLVQMAWTFINDSLSTTLCLKHRSEVIANAMLALAAKLN 198

[Close]

BLAST of Cyclin-C vs. Ensembl Nematostella
Match: EDO42905 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S058])

HSP 1 Score: 44.2838 bits (103), Expect = 1.011e-9
Identity = 21/76 (27.63%), Postives = 38/76 (50.00%), Query Frame = 1

Query:  166 FGEKLGLRQQVIATAVTYFKRFYAMYSLKSVDPWLMGQTALFLASKIEEFGLVSQKSIIQTCNSLNKNSPNISPEN 393
             G++L + Q  I T++ Y  RFY  +  +      M    LFL++K+EE     +  I      L+++ P ++PE+
Sbjct:   49 MGQRLSVSQLTINTSIVYMHRFYMCHPFQKFHRHAMAPCCLFLSAKVEEQPRKLEHVIRVAHACLHRDGPPLNPES 124

HSP 2 Score: 35.8094 bits (81), Expect = 1.011e-9
Identity = 23/87 (26.44%), Postives = 46/87 (52.87%), Query Frame = 3

Query:  390 EYPHKIQDVLDCEFILVEVLDCSLIVFHPYRSLLLYSENLSTSPNYQHDSSILQKAWKIVNDSLR-TDLMLYYPPYLISLGCLFLAC 647
            EY  + QD+++ E IL++ L   + V HP+  ++   + +  S +      + Q ++ +  +SL  T L L + P +++  C+ LAC
Sbjct:  126 EYLQQAQDLIENESILLQTLGFEVTVHHPHTYVVKGIQLVRASKD------LGQASYFMATNSLHLTTLCLQFKPPVVACACIHLAC 206

[Close]

BLAST of Cyclin-C vs. Ensembl Medaka
Match: ccnc (cyclin C [Source:NCBI gene;Acc:101157177])

HSP 1 Score: 147.132 bits (370), Expect = 6.063e-72
Identity = 68/151 (45.03%), Postives = 105/151 (69.54%), Query Frame = 3

Query:  357 FKQKFSQYFPREYPHKIQDVLDCEFILVEVLDCSLIVFHPYRSLLLYSENLSTSPNYQHDSSILQKAWKIVNDSLRTDLMLYYPPYLISLGCLFLACVMDKKNEEAIQSWFADLLVDFSKVMEVVKTMTGLYCLWKNCDDDKDIFNLLSKM 809
             K +FS  FP+E+P+++  +L+CEF L+E++DC LIV+HPYR LL Y +++        +  +L  AW+IVND+ RTDL L YPP++I+L CL +ACV+ +K+    + WFA+L VD  K++E+++ +  LY  WKN DD K+I  +L+KM
Sbjct:  116 LKTRFSYAFPKEFPYRMNHILECEFYLLELMDCCLIVYHPYRPLLQYVQDMG------QEDMLLPLAWRIVNDTYRTDLCLLYPPFMIALACLHVACVVQQKDA---RQWFAELSVDMDKILEIIRVILKLYDQWKNFDDRKEIAAVLNKM 257

HSP 2 Score: 143.665 bits (361), Expect = 6.063e-72
Identity = 72/119 (60.50%), Postives = 87/119 (73.11%), Query Frame = 1

Query:   13 MAGNFWRSSHCLEWLLDKQYVLKNRESDIKELGGEDEYQKLMIFFTGVTFSFGEKLGLRQQVIATAVTYFKRFYAMYSLKSVDPWLMGQTALFLASKIEEFGLVSQKSIIQTCNSLNKN 369
            MAGNFW+SSH L+W+LDKQ ++K R+ D+K L  E+EY KL IFF  V  + GE L LRQQVIATA  YFKRFYA YSLKS+DP LM  T +FLASK+EEFG+VS   +I    S+ K 
Sbjct:    1 MAGNFWQSSHYLQWVLDKQDLIKERQKDLKFLS-EEEYWKLQIFFANVIQALGEHLKLRQQVIATATVYFKRFYARYSLKSIDPVLMAPTCVFLASKVEEFGVVSNTRLISAATSVLKT 118

[Close]

BLAST of Cyclin-C vs. Ensembl Medaka
Match: ccnc (cyclin C [Source:NCBI gene;Acc:101157177])

HSP 1 Score: 144.436 bits (363), Expect = 3.181e-64
Identity = 72/119 (60.50%), Postives = 87/119 (73.11%), Query Frame = 1

Query:   13 MAGNFWRSSHCLEWLLDKQYVLKNRESDIKELGGEDEYQKLMIFFTGVTFSFGEKLGLRQQVIATAVTYFKRFYAMYSLKSVDPWLMGQTALFLASKIEEFGLVSQKSIIQTCNSLNKN 369
            MAGNFW+SSH L+W+LDKQ ++K R+ D+K L  E+EY KL IFF  V  + GE L LRQQVIATA  YFKRFYA YSLKS+DP LM  T +FLASK+EEFG+VS   +I    S+ K 
Sbjct:    1 MAGNFWQSSHYLQWVLDKQDLIKERQKDLKFLS-EEEYWKLQIFFANVIQALGEHLKLRQQVIATATVYFKRFYARYSLKSIDPVLMAPTCVFLASKVEEFGVVSNTRLISAATSVLKT 118

HSP 2 Score: 120.553 bits (301), Expect = 3.181e-64
Identity = 56/121 (46.28%), Postives = 84/121 (69.42%), Query Frame = 3

Query:  357 FKQKFSQYFPREYPHKIQDVLDCEFILVEVLDCSLIVFHPYRSLLLYSENLSTSPNYQHDSSILQKAWKIVNDSLRTDLMLYYPPYLISLGCLFLACVMDKKNEEAIQSWFADLLVDFSKV 719
             K +FS  FP+E+P+++  +L+CEF L+E++DC LIV+HPYR LL Y +++        +  +L  AW+IVND+ RTDL L YPP++I+L CL +ACV+ +K+    + WFA+L VD  KV
Sbjct:  116 LKTRFSYAFPKEFPYRMNHILECEFYLLELMDCCLIVYHPYRPLLQYVQDMG------QEDMLLPLAWRIVNDTYRTDLCLLYPPFMIALACLHVACVVQQKDA---RQWFAELSVDMDKV 227

[Close]

BLAST of Cyclin-C vs. Ensembl Medaka
Match: ccnk (cyclin K [Source:NCBI gene;Acc:101155650])

HSP 1 Score: 53.5286 bits (127), Expect = 1.022e-15
Identity = 36/104 (34.62%), Postives = 51/104 (49.04%), Query Frame = 1

Query:   52 WLLDKQYVLKN-RESDIKELGGEDEYQKLMIFFTGVTFSFGEKLGLRQQVIATAVTYFKRFYAMYSLKSVDPWLMGQTALFLASKIEEFGLVSQKSIIQTCNSL 360
            W  DK+ +     +S+  + G E  Y++    F    F  G +LGL    +AT + YF RFY  +S K    ++ G   LFLA K+EE      K II+T  SL
Sbjct:   39 WYWDKKDLAHTPSQSEGLDPGTEARYRREGARFI---FDVGTRLGLHYDTLATGIIYFHRFYMFHSFKQFPRYVTGACCLFLAGKVEETPKKC-KDIIKTARSL 138

HSP 2 Score: 48.521 bits (114), Expect = 1.022e-15
Identity = 34/93 (36.56%), Postives = 50/93 (53.76%), Query Frame = 3

Query:  408 QDVLDCEFILVEVLDCSLIVFHPYRSLLLYSENLSTSPNYQHDSSILQKAWKIVNDSLRTDLMLYYPPYLISLGCLFLACVMDKKNEEAIQSW 686
            ++V+  E IL++ +   L V HPY  LL Y + L    N      +LQ AW  VNDSL T L L + P +I++  ++LA  + K +   IQ W
Sbjct:  153 EEVMVLERILLQTIKFDLQVEHPYMFLLRYVKQLKGDKN--KVCKVLQMAWTFVNDSLCTMLSLQWEPEIIAVAVMYLAGRLCKFD---IQEW 240

[Close]

BLAST of Cyclin-C vs. Ensembl Medaka
Match: ccnq (cyclin Q [Source:NCBI gene;Acc:101174665])

HSP 1 Score: 43.8986 bits (102), Expect = 4.835e-8
Identity = 20/69 (28.99%), Postives = 37/69 (53.62%), Query Frame = 1

Query:  166 FGEKLGLRQQVIATAVTYFKRFYAMYSLKSVDPWLMGQTALFLASKIEEFGLVSQKSIIQTCNSLNKNS 372
             G KLG+    +ATA   + RF+    L+  +P+L+  + ++LA K+EE  + ++  +  +    NK S
Sbjct:   49 IGVKLGMHSIPVATACVLYHRFFKRVCLREYEPYLVAMSCVYLAGKVEEQHIRTRDIVNVSHRYFNKGS 117

HSP 2 Score: 31.9574 bits (71), Expect = 4.835e-8
Identity = 16/80 (20.00%), Postives = 41/80 (51.25%), Query Frame = 3

Query:  411 DVLDCEFILVEVLDCSLIVFHPYRSLLLYSENLSTSPNYQ--HDSSILQKAWKIVNDSLRTDLMLYYPPYLISLGCLFLA 644
             V+ CE +++  L   + + HP++ LL +  ++ +  N      + + + +W ++ D    ++ + + P  I++  L+LA
Sbjct:  132 SVVQCELLILRQLGFHVSIEHPHKYLLHFLLSVKSLVNRHAWSRTPVAETSWALLRDCYHGNMSIRHTPQHIAIATLYLA 211

[Close]

Query:  166 FGEKLGLRQQVIATAVTYFKRFYAMYSLKSVDPWLMGQTALFLASKIEEFGLVSQKSIIQTCNSLNKNS 372
             G KLG+    +ATA   + RF+    L+  +P+L+  + ++LA K+EE  + ++  +  +    NK S
Sbjct:   49 IGVKLGMHSIPVATACVLYHRFFKRVCLREYEPYLVAMSCVYLAGKVEEQHIRTRDIVNVSHRYFNKGS 117

HSP 2 Score: 31.9574 bits (71), Expect = 4.835e-8
Identity = 16/80 (20.00%), Postives = 41/80 (51.25%), Query Frame = 3

Query:  411 DVLDCEFILVEVLDCSLIVFHPYRSLLLYSENLSTSPNYQ--HDSSILQKAWKIVNDSLRTDLMLYYPPYLISLGCLFLA 644
             V+ CE +++  L   + + HP++ LL +  ++ +  N      + + + +W ++ D    ++ + + P  I++  L+LA
Sbjct:  132 SVVQCELLILRQLGFHVSIEHPHKYLLHFLLSVKSLVNRHAWSRTPVAETSWALLRDCYHGNMSIRHTPQHIAIATLYLA 211

[Close]

BLAST of Cyclin-C vs. Planmine SMEST
Match: SMESG000028921.1 (SMESG000028921.1)

HSP 1 Score: 393.66 bits (1010), Expect = 1.221e-175
Identity = 188/188 (100.00%), Postives = 188/188 (100.00%), Query Frame = 3

Query:  360 KQKFSQYFPREYPHKIQDVLDCEFILVEVLDCSLIVFHPYRSLLLYSENLSTSPNYQHDSSILQKAWKIVNDSLRTDLMLYYPPYLISLGCLFLACVMDKKNEEAIQSWFADLLVDFSKVMEVVKTMTGLYCLWKNCDDDKDIFNLLSKMPKPKIHNANQQHNISHQQVSNNNVMKSNVIQHQASRTK 923
            KQKFSQYFPREYPHKIQDVLDCEFILVEVLDCSLIVFHPYRSLLLYSENLSTSPNYQHDSSILQKAWKIVNDSLRTDLMLYYPPYLISLGCLFLACVMDKKNEEAIQSWFADLLVDFSKVMEVVKTMTGLYCLWKNCDDDKDIFNLLSKMPKPKIHNANQQHNISHQQVSNNNVMKSNVIQHQASRTK
Sbjct:  118 KQKFSQYFPREYPHKIQDVLDCEFILVEVLDCSLIVFHPYRSLLLYSENLSTSPNYQHDSSILQKAWKIVNDSLRTDLMLYYPPYLISLGCLFLACVMDKKNEEAIQSWFADLLVDFSKVMEVVKTMTGLYCLWKNCDDDKDIFNLLSKMPKPKIHNANQQHNISHQQVSNNNVMKSNVIQHQASRTK 305

HSP 2 Score: 242.662 bits (618), Expect = 1.221e-175
Identity = 116/118 (98.31%), Postives = 117/118 (99.15%), Query Frame = 1

Query:   13 MAGNFWRSSHCLEWLLDKQYVLKNRESDIKELGGEDEYQKLMIFFTGVTFSFGEKLGLRQQVIATAVTYFKRFYAMYSLKSVDPWLMGQTALFLASKIEEFGLVSQKSIIQTCNSLNK 366
            MAGNFWRSSHCLEWLLDKQYVLKNRESDIKELGGEDEYQKLMIFFTGVTFSFGEKLGLRQQVIATAVTYFKRFYAMYSLKSVDPWLMGQTALFLASKIEEFGLVSQKSIIQTCNS+ K
Sbjct:    1 MAGNFWRSSHCLEWLLDKQYVLKNRESDIKELGGEDEYQKLMIFFTGVTFSFGEKLGLRQQVIATAVTYFKRFYAMYSLKSVDPWLMGQTALFLASKIEEFGLVSQKSIIQTCNSVIK 118

[Close]

BLAST of Cyclin-C vs. Planmine SMEST
Match: SMESG000004055.1 (SMESG000004055.1)

HSP 1 Score: 55.4546 bits (132), Expect = 1.303e-17
Identity = 32/113 (28.32%), Postives = 62/113 (54.87%), Query Frame = 3

Query:  408 QDVLDCEFILVEVLDCSLIVFHPYRSLLLYSENLSTSPNYQHDSSILQKAWKIVNDSLRTDLMLYYPPYLISLGCLFLACVMDKK------NEEAIQSWFADLLVDFS-KVME 725
            ++++  E IL++ +   L V HPY+ LL Y + +       +   ++Q +W  +NDSLRT+L L + P +++   L+LA  ++K+      N++  Q W+   +   + +VME
Sbjct:  123 EEIMTMERILLKTIKFDLQVSHPYKYLLNYVQKIKG--KQTNVERLVQMSWTFINDSLRTNLCLKWEPEIVACAVLYLATKLNKQEIESWENQQVGQKWWESFVEGMTIEVME 233

HSP 2 Score: 52.7582 bits (125), Expect = 1.303e-17
Identity = 29/68 (42.65%), Postives = 38/68 (55.88%), Query Frame = 1

Query:  115 EDEYQKLMIFFTGVTF--SFGEKLGLRQQVIATAVTYFKRFYAMYSLKSVDPWLMGQTALFLASKIEE 312
            ED+Y+       G TF    G KLGL+    ATA+ YF RFY  +S K++  +L     LFLA K+EE
Sbjct:   31 EDKYRN-----EGATFISELGNKLGLKYDTCATAMVYFHRFYMFHSFKTMPRFLTASCCLFLAGKVEE 93

[Close]

BLAST of Cyclin-C vs. Planmine SMEST
Match: SMESG000064359.1 (SMESG000064359.1)

HSP 1 Score: 40.4318 bits (93), Expect = 2.848e-7
Identity = 28/117 (23.93%), Postives = 57/117 (48.72%), Query Frame = 1

Query:   25 FWRSSHCLEWLLDKQYVLKNRE---------------SDIKE--LGGEDEYQKLMIFFTGVTFSFGEKLG-LRQQVIATAVTYFKRFYAMYSLKSVDPWLMGQTALFLASKIEEFGL 321
            F +S+    W+  K+ + + R+                DI+   + G++E + + +F + +   + + +  L  QV   +VTYF+RF+  +S+    P  +  TA+++A KI EF +
Sbjct:    3 FEKSTQSARWIFSKEQLFELRKKANNNSKAQLRKYFNDDIQHCFINGDEELKVVNLFLSMIRHFYRKFVPTLPIQVFGVSVTYFRRFFLKHSVMDFHPREIIVTAIYIACKILEFSI 119

HSP 2 Score: 32.7278 bits (73), Expect = 2.848e-7
Identity = 24/103 (23.30%), Postives = 46/103 (44.66%), Query Frame = 3

Query:  414 VLDCEFILVEVLDCSLIVFHPY---RSLLLYSENLST--------SPNYQHD--------------SSILQKAWKIVNDSLRTDLMLYYPPYLISLGCLFLAC 647
            + + E+ L++ LD  L V+ PY   +S ++     S         S +Y+ +              +  +Q  + I+ND   TDLM+ + P  ++LG + + C
Sbjct:  139 IYNSEWFLIDQLDFDLWVYTPYEPFKSFMVEFRTFSIEKELMNVMSDHYEGELNRIINDPTLNRQFNDTVQSGYNIINDWYETDLMMIFKPNDVALGVVEVCC 241

The following BLAST results are available for this feature:

BLAST of Cyclin-C vs. Ensembl Human
BLAST of Cyclin-C vs. Ensembl Celegans
BLAST of Cyclin-C vs. Ensembl Fly
BLAST of Cyclin-C vs. Ensembl Zebrafish
BLAST of Cyclin-C vs. Ensembl Xenopus
BLAST of Cyclin-C vs. Ensembl Mouse
BLAST of Cyclin-C vs. UniProt/SwissProt
BLAST of Cyclin-C vs. TrEMBL
BLAST of Cyclin-C vs. Ensembl Cavefish
BLAST of Cyclin-C vs. Ensembl Sea Lamprey
BLAST of Cyclin-C vs. Ensembl Yeast
BLAST of Cyclin-C vs. Ensembl Nematostella
BLAST of Cyclin-C vs. Ensembl Medaka
BLAST of Cyclin-C vs. Planmine SMEST

BLAST of Cyclin-C vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
CCNC	6.480e-73	62.18	cyclin C [Source:HGNC Symbol;Acc:HGNC:1581]	[more]
CCNC	6.480e-73	62.18	cyclin C [Source:HGNC Symbol;Acc:HGNC:1581]	[more]
CCNC	9.812e-73	44.37	cyclin C [Source:HGNC Symbol;Acc:HGNC:1581]	[more]
CCNC	4.482e-71	62.18	cyclin C [Source:HGNC Symbol;Acc:HGNC:1581]	[more]
CCNC	3.418e-57	62.18	cyclin C [Source:HGNC Symbol;Acc:HGNC:1581]	[more]

BLAST of Cyclin-C vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
cic-1	8.223e-23	35.96	Cyclin-C [Source:UniProtKB/Swiss-Prot;Acc:Q9TYP2]	[more]
cyl-1	2.359e-9	30.00	cyclin L [Source:UniProtKB/TrEMBL;Acc:G5EBX3]	[more]
cyl-1	2.359e-9	30.00	cyclin L [Source:UniProtKB/TrEMBL;Acc:G5EBX3]	[more]
ccnk-1	1.112e-8	31.76	CyCliN K [Source:UniProtKB/TrEMBL;Acc:O17869]	[more]
ccnk-1	1.112e-8	31.76	CyCliN K [Source:UniProtKB/TrEMBL;Acc:O17869]	[more]

BLAST of Cyclin-C vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
CycC	1.904e-65	56.52	gene:FBgn0004597 transcript:FBtr0083010	[more]
CycK	1.273e-12	32.26	gene:FBgn0025674 transcript:FBtr0344022	[more]
CycK	1.273e-12	32.26	gene:FBgn0025674 transcript:FBtr0085942	[more]
CycK	1.273e-12	32.26	gene:FBgn0025674 transcript:FBtr0085941	[more]
CycT	8.657e-8	28.70	gene:FBgn0025455 transcript:FBtr0333124	[more]

BLAST of Cyclin-C vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ccnc	6.839e-71	60.50	cyclin C [Source:ZFIN;Acc:ZDB-GENE-030131-7369]	[more]
ccnk	1.060e-16	33.98	cyclin K [Source:NCBI gene;Acc:569432]	[more]
ccnk	1.416e-16	33.98	cyclin K [Source:NCBI gene;Acc:569432]	[more]
ccnq	1.822e-7	34.94	cyclin Q [Source:NCBI gene;Acc:553650]	[more]
ccnq	1.822e-7	34.94	cyclin Q [Source:NCBI gene;Acc:553650]	[more]

BLAST of Cyclin-C vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ccnc	3.053e-72	62.18	cyclin C [Source:NCBI gene;Acc:394762]	[more]
ccnc	3.750e-60	60.55	cyclin C [Source:NCBI gene;Acc:394762]	[more]
ccnk	6.950e-16	35.24	cyclin K [Source:NCBI gene;Acc:779776]	[more]
ccnk	7.384e-16	41.79	cyclin K [Source:NCBI gene;Acc:779776]	[more]
ccnk	7.699e-16	41.79	cyclin K [Source:NCBI gene;Acc:779776]	[more]

BLAST of Cyclin-C vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Ccnc	5.787e-73	44.37	cyclin C [Source:MGI Symbol;Acc:MGI:1858199]	[more]
Ccnc	5.787e-73	44.37	cyclin C [Source:MGI Symbol;Acc:MGI:1858199]	[more]
Ccnc	8.065e-73	44.37	cyclin C [Source:MGI Symbol;Acc:MGI:1858199]	[more]
Ccnc	8.482e-73	44.37	cyclin C [Source:MGI Symbol;Acc:MGI:1858199]	[more]
Ccnk	2.730e-16	32.77	cyclin K [Source:MGI Symbol;Acc:MGI:1276106]	[more]

BLAST of Cyclin-C vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q3ZCK5\|CCNC_BOVIN	1.712e-72	45.70	Cyclin-C OS=Bos taurus OX=9913 GN=CCNC PE=2 SV=1	[more]
sp\|P24863\|CCNC_HUMAN	4.231e-72	44.37	Cyclin-C OS=Homo sapiens OX=9606 GN=CCNC PE=1 SV=2	[more]
sp\|P55168\|CCNC_CHICK	4.484e-72	44.37	Cyclin-C OS=Gallus gallus OX=9031 GN=CCNC PE=3 SV=...	[more]
sp\|Q4KLA0\|CCNC_XENLA	4.636e-72	44.37	Cyclin-C OS=Xenopus laevis OX=8355 GN=ccnc PE=2 SV...	[more]
sp\|Q62447\|CCNC_MOUSE	4.792e-72	44.37	Cyclin-C OS=Mus musculus OX=10090 GN=Ccnc PE=2 SV=...	[more]

BLAST of Cyclin-C vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
D2DJV1	4.997e-103	81.37	CyclinC-like protein (Fragment) OS=Schmidtea medit...	[more]
A0A0L8IHF8	4.767e-74	49.35	Uncharacterized protein OS=Octopus bimaculoides OX...	[more]
T1IVG7	1.768e-73	44.94	Uncharacterized protein OS=Strigamia maritima OX=1...	[more]
V4B3J3	1.705e-72	45.51	Uncharacterized protein OS=Lottia gigantea OX=2251...	[more]
A0A4W5KWB1	4.111e-72	42.13	Cyclin C OS=Hucho hucho OX=62062 PE=3 SV=1	[more]

BLAST of Cyclin-C vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ccnk	7.829e-16	41.79	cyclin K [Source:NCBI gene;Acc:103046138]	[more]
ccnq	3.278e-7	33.87	cyclin Q [Source:NCBI gene;Acc:103022361]	[more]
ccnt2b	5.544e-7	38.78	cyclin-T2-like [Source:NCBI gene;Acc:103028284]	[more]
ccnt2a	8.537e-7	38.78	cyclin T2 [Source:NCBI gene;Acc:103023729]	[more]
ccnt2b	9.758e-7	38.78	cyclin-T2-like [Source:NCBI gene;Acc:103028284]	[more]

BLAST of Cyclin-C vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ccnc	1.318e-63	42.50	cyclin C [Source:ZFIN;Acc:ZDB-GENE-030131-7369]	[more]
ENSPMAT00000003409.1	6.889e-14	35.71	pep scaffold:Pmarinus_7.0:GL483875:8555:11659:-1 g...	[more]
ENSPMAT00000003411.1	1.106e-13	39.44	pep scaffold:Pmarinus_7.0:GL483875:8648:11677:-1 g...	[more]
ccnq	2.360e-8	32.22	cyclin Q [Source:NCBI gene;Acc:553650]	[more]
ENSPMAT00000007549.1	1.277e-7	44.44	pep scaffold:Pmarinus_7.0:GL483420:1071:10573:1 ge...	[more]

BLAST of Cyclin-C vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 2


Match Name	E-value	Identity	Description
SSN8	6.337e-19	30.92	Cyclin-like component of the RNA polymerase II hol...	[more]
CCL1	1.262e-9	32.00	Cyclin associated with protein kinase Kin28p; Kin2...	[more]

BLAST of Cyclin-C vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 4


Match Name	E-value	Identity	Description
EDO32917	7.071e-65	42.50	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO45644	1.168e-14	36.11	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO48578	3.765e-12	45.31	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO42905	1.011e-9	27.63	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of Cyclin-C vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ccnc	6.063e-72	45.03	cyclin C [Source:NCBI gene;Acc:101157177]	[more]
ccnc	3.181e-64	60.50	cyclin C [Source:NCBI gene;Acc:101157177]	[more]
ccnk	1.022e-15	34.62	cyclin K [Source:NCBI gene;Acc:101155650]	[more]
ccnq	4.835e-8	28.99	cyclin Q [Source:NCBI gene;Acc:101174665]	[more]
ccnq	4.835e-8	28.99	cyclin Q [Source:NCBI gene;Acc:101174665]	[more]

BLAST of Cyclin-C vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 3


Match Name	E-value	Identity	Description
SMESG000028921.1	1.221e-175	100.00	SMESG000028921.1	[more]
SMESG000004055.1	1.303e-17	28.32	SMESG000004055.1	[more]
SMESG000064359.1	2.848e-7	23.93	SMESG000064359.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence
protein sequence

transcript sequence

>SMED30017453 ID=SMED30017453|Name=Cyclin-C|organism=Schmidtea mediterranea sexual|type=transcript|length=997bp
CTCAATCAAATTATGGCTGGAAATTTTTGGCGAAGTTCTCATTGTTTGGA
ATGGCTTCTTGATAAACAGTATGTTCTGAAGAATAGAGAAAGTGACATTA
AGGAGTTGGGTGGTGAAGATGAATATCAAAAGCTTATGATATTTTTTACC
GGGGTTACTTTTTCTTTTGGTGAGAAGTTGGGCCTTCGACAACAAGTTAT
AGCAACTGCTGTTACTTATTTTAAAAGATTTTATGCAATGTATTCATTGA
AGTCAGTTGATCCTTGGTTAATGGGTCAAACTGCACTATTTCTAGCTTCT
AAAATAGAAGAATTTGGTTTAGTATCTCAAAAAAGTATTATTCAGACATG
TAATAGTTTAAACAAAAATTCTCCCAATATTTCCCCAGAGAATATCCTCA
TAAAATTCAAGATGTATTGGACTGTGAATTTATCTTAGTTGAAGTCTTGG
ATTGTTCTTTAATTGTGTTTCATCCATACAGATCTTTACTCTTGTATTCT
GAAAATCTCTCTACATCACCAAATTATCAACACGATTCTAGTATTTTACA
AAAAGCTTGGAAAATTGTAAATGATAGTTTACGAACAGATCTGATGCTAT
ATTATCCGCCGTATCTCATCTCTCTGGGATGTCTGTTTTTGGCGTGCGTA
ATGGACAAGAAGAATGAAGAAGCAATTCAATCGTGGTTTGCAGATCTATT
GGTGGATTTCAGCAAAGTAATGGAAGTTGTGAAAACCATGACAGGTTTAT
ATTGTCTGTGGAAAAATTGTGATGATGATAAAGACATTTTTAACTTACTA
TCAAAAATGCCAAAACCAAAAATTCACAATGCCAATCAACAGCATAATAT
TTCCCATCAACAAGTATCCAACAATAACGTAATGAAATCCAATGTAATTC
AGCATCAAGCCTCTCGTACTAAATGAATATAAACGAAATAATTTCCTTTG
ATTTGTTTGTAATTTATAAGATTTTTAAATAAATGTTTTTATGAAAA

protein sequence of SMED30017453-orf-1

>SMED30017453-orf-1 ID=SMED30017453-orf-1|Name=SMED30017453-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=111bp
MLYYPPYLISLGCLFLACVMDKKNEEAIQSWFADLLVDFSKVMEVVKTMT
GLYCLWKNCDDDKDIFNLLSKMPKPKIHNANQQHNISHQQVSNNNVMKSN
VIQHQASRTK*

protein sequence of SMED30017453-orf-2

>SMED30017453-orf-2 ID=SMED30017453-orf-2|Name=SMED30017453-orf-2|organism=Schmidtea mediterranea sexual|type=polypeptide|length=146bp
LNQIMAGNFWRSSHCLEWLLDKQYVLKNRESDIKELGGEDEYQKLMIFFT
GVTFSFGEKLGLRQQVIATAVTYFKRFYAMYSLKSVDPWLMGQTALFLAS
KIEEFGLVSQKSIIQTCNSLNKNSPNISPENILIKFKMYWTVNLS*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **biological process**
Term	Definition
GO:0000079	regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0006357	regulation of transcription from RNA polymerase II promoter
GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0045737	positive regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:1901409	positive regulation of phosphorylation of RNA polymerase II C-terminal domain

Vocabulary: **cellular component**
Term	Definition
GO:0042025	host cell nucleus
GO:0000307	cyclin-dependent protein kinase holoenzyme complex
GO:0005634	nucleus
GO:0016592	mediator complex

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000101	muscle cell
PLANA:0000142	posterior region of the whole animal

Vocabulary: **INTERPRO**
Term	Definition
IPR043198	Cyclin/Ssn8
IPR028367	CyclinC/Ssn8
IPR036915	Cyclin-like_sf
IPR013763	Cyclin-like
IPR006671	Cyclin_N

Vocabulary: **molecular function**
Term	Definition
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
None	No IPR available	GENE3D	G3DSA:1.10.472.10		coord: 25..141 e-value: 1.8E-27 score: 97.7
IPR006671	Cyclin, N-terminal	PFAM	PF00134	Cyclin_N	coord: 55..118 e-value: 9.8E-10 score: 38.3
IPR043198	Cyclin/Cyclin-like subunit Ssn8	PANTHER	PTHR10026	CYCLIN	coord: 9..127
IPR028367	Cyclin C/cyclin-like subunit Ssn8	PANTHER	PTHR10026:SF7	CYCLIN-C	coord: 9..127
IPR013763	Cyclin-like	CDD	cd00043	CYCLIN	coord: 56..123 e-value: 3.72666E-10 score: 51.4705
IPR036915	Cyclin-like superfamily	SUPERFAMILY	SSF47954	Cyclin-like	coord: 8..121