Serine/threonine-protein kinase OSR1
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30017401 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 2
Homology
BLAST of Serine/threonine-protein kinase OSR1 vs. Ensembl Human
Match: STK39 (serine/threonine kinase 39 [Source:HGNC Symbol;Acc:HGNC:17717]) HSP 1 Score: 339.732 bits (870), Expect = 3.040e-109 Identity = 202/500 (40.40%), Postives = 293/500 (58.60%), Query Frame = 2
Query: 146 WSNKREDYKINRSIGQGATSNVYEAECLPLNNRLCAMKIINLEKCNSSSLLEEIKREIKSMKNMKNENIVTYYASFVNGIELFIIMDVCQRGSLLDIIKRTQSKRDITYGVFDESTIATILKDVLRGLTYIHENGLVHRDLKCGNLLVKDDGIIQIADFGVAAFLAAQPMHTTGASLDNK-RFTFVGTPCWMAPEVMQQVKGHNQKADIWSLGITAIELAAGQAPYAKYAPMKVLMLTLQNESPDIDTAASSCNQYSNYGQKYRKFSKACLNKDPAMRPSAKELLQSPFIKSKAKDRDSLIKVLLSEDTLPFERQRSDE-NLCPEKTP--TKAFSGEWNFDLQPLGDHLNDIDNKESVDKTE----------------------------------NETFENSEPISYRITLRKRNPKKNNELEDISFDYVIGKDSVELLVRELVEADLLDGCDLLLVAHNMSELVANP-SVRERVFALNSP-PSTGVANEQELYGYAKV 1525
W R+ Y++ IG GAT+ V A C P R+ A+K INLEKC +S ++E+ +EI++M + N+VTYY SFV EL+++M + GS+LDIIK ++ + GV +E+ IATILK+VL GL Y+H NG +HRDLK GN+L+ +DG +QIADFGV+AFLA T G NK R TFVGTPCWMAPEVM+QV+G++ KAD+WS GITAIELA G APY KY PMKVLMLTLQN+ P ++T YG+ +RK CL KDP+ RP+A ELL+ F + KAK+R+ LI+ LL+ P QR+ + P + K G+W + + + + S +K+ NE + + + + LR RN +K EL DI F++ G+D+ + + +EL A L+DG D+++VA N+ ++V +P +++ F L S + + +E +L G+A++
Sbjct: 56 WPICRDAYELQEVIGSGATAVVQAALCKPRQERV-AIKRINLEKCQTS--MDELLKEIQAMSQCSHPNVVTYYTSFVVKDELWLVMKLLSGGSMLDIIKYIVNRGEHKNGVLEEAIIATILKEVLEGLDYLHRNGQIHRDLKAGNILLGEDGSVQIADFGVSAFLA-----TGGDVTRNKVRKTFVGTPCWMAPEVMEQVRGYDFKADMWSFGITAIELATGAAPYHKYPPMKVLMLTLQNDPPTLETGVEDKEMMKKYGKSFRKLLSLCLQKDPSKRPTAAELLKCKFFQ-KAKNREYLIEKLLTR--TPDIAQRAKKVRRVPGSSGHLHKTEDGDWEWSDDEMDEKSEEGKAAFSQEKSRRVKEENPEIAVSASTIPEQIQSLSVHDSQGPPNANEDYREASSCAVNLVLRLRNSRK--ELNDIRFEFTPGRDTADGVSQELFSAGLVDGHDVVIVAANLQKIVDDPKALKTLTFKLASGCDGSEIPDEVKLIGFAQL 542
BLAST of Serine/threonine-protein kinase OSR1 vs. Ensembl Human
Match: OXSR1 (oxidative stress responsive kinase 1 [Source:HGNC Symbol;Acc:HGNC:8508]) HSP 1 Score: 316.62 bits (810), Expect = 3.066e-101 Identity = 163/310 (52.58%), Postives = 212/310 (68.39%), Query Frame = 2
Query: 146 WSNKREDYKINRSIGQGATSNVYEAECLPLNNRLCAMKIINLEKCNSSSLLEEIKREIKSMKNMKNENIVTYYASFVNGIELFIIMDVCQRGSLLDIIKRTQSKRDITYGVFDESTIATILKDVLRGLTYIHENGLVHRDLKCGNLLVKDDGIIQIADFGVAAFLAAQPMHTTGASLDNK-RFTFVGTPCWMAPEVMQQVKGHNQKADIWSLGITAIELAAGQAPYAKYAPMKVLMLTLQNESPDIDTAASSCNQYSNYGQKYRKFSKACLNKDPAMRPSAKELLQSPFIKSKAKDRDSLIKVLLSEDTL 1072
WS R+DY++ IG GAT+ V A C P ++ A+K INLEKC +S ++E+ +EI++M + NIV+YY SFV EL+++M + GS+LDIIK +K + GV DESTIATIL++VL GL Y+H+NG +HRD+K GN+L+ +DG +QIADFGV+AFLA T G NK R TFVGTPCWMAPEVM+QV+G++ KADIWS GITAIELA G APY KY PMKVLMLTLQN+ P ++T YG+ +RK CL KDP RP+A ELL+ F + KAK+++ L E TL
Sbjct: 10 WSINRDDYELQEVIGSGATAVVQAAYCAPKKEKV-AIKRINLEKCQTS--MDELLKEIQAMSQCHHPNIVSYYTSFVVKDELWLVMKLLSGGSVLDIIKHIVAKGEHKSGVLDESTIATILREVLEGLEYLHKNGQIHRDVKAGNILLGEDGSVQIADFGVSAFLA-----TGGDITRNKVRKTFVGTPCWMAPEVMEQVRGYDFKADIWSFGITAIELATGAAPYHKYPPMKVLMLTLQNDPPSLETGVQDKEMLKKYGKSFRKMISLCLQKDPEKRPTAAELLRHKFFQ-KAKNKE-----FLQEKTL 305
BLAST of Serine/threonine-protein kinase OSR1 vs. Ensembl Human
Match: OXSR1 (oxidative stress responsive kinase 1 [Source:HGNC Symbol;Acc:HGNC:8508]) HSP 1 Score: 317.005 bits (811), Expect = 1.093e-100 Identity = 163/310 (52.58%), Postives = 212/310 (68.39%), Query Frame = 2
Query: 146 WSNKREDYKINRSIGQGATSNVYEAECLPLNNRLCAMKIINLEKCNSSSLLEEIKREIKSMKNMKNENIVTYYASFVNGIELFIIMDVCQRGSLLDIIKRTQSKRDITYGVFDESTIATILKDVLRGLTYIHENGLVHRDLKCGNLLVKDDGIIQIADFGVAAFLAAQPMHTTGASLDNK-RFTFVGTPCWMAPEVMQQVKGHNQKADIWSLGITAIELAAGQAPYAKYAPMKVLMLTLQNESPDIDTAASSCNQYSNYGQKYRKFSKACLNKDPAMRPSAKELLQSPFIKSKAKDRDSLIKVLLSEDTL 1072
WS R+DY++ IG GAT+ V A C P ++ A+K INLEKC +S ++E+ +EI++M + NIV+YY SFV EL+++M + GS+LDIIK +K + GV DESTIATIL++VL GL Y+H+NG +HRD+K GN+L+ +DG +QIADFGV+AFLA T G NK R TFVGTPCWMAPEVM+QV+G++ KADIWS GITAIELA G APY KY PMKVLMLTLQN+ P ++T YG+ +RK CL KDP RP+A ELL+ F + KAK+++ L E TL
Sbjct: 10 WSINRDDYELQEVIGSGATAVVQAAYCAPKKEKV-AIKRINLEKCQTS--MDELLKEIQAMSQCHHPNIVSYYTSFVVKDELWLVMKLLSGGSVLDIIKHIVAKGEHKSGVLDESTIATILREVLEGLEYLHKNGQIHRDVKAGNILLGEDGSVQIADFGVSAFLA-----TGGDITRNKVRKTFVGTPCWMAPEVMEQVRGYDFKADIWSFGITAIELATGAAPYHKYPPMKVLMLTLQNDPPSLETGVQDKEMLKKYGKSFRKMISLCLQKDPEKRPTAAELLRHKFFQ-KAKNKE-----FLQEKTL 305 HSP 2 Score: 60.077 bits (144), Expect = 7.729e-9 Identity = 39/100 (39.00%), Postives = 61/100 (61.00%), Query Frame = 2
Query: 1232 ENSEPISYRITLRKRNPKKNNELEDISFDYVIGKDSVELLVRELVEADLLDGCDLLLVAHNMSELVANP-SVRERVFALNSP-PSTGVANEQELYGYAKV 1525
E PIS + LR RN KK EL DI F++ G+D+ E + +EL+ A L+DG DL++VA N+ ++V P S R F L S + + ++ +L G+A++
Sbjct: 429 ETKIPIS--LVLRLRNSKK--ELNDIRFEFTPGRDTAEGVSQELISAGLVDGRDLVIVAANLQKIVEEPQSNRSVTFKLASGVEGSDIPDDGKLIGFAQL 524
BLAST of Serine/threonine-protein kinase OSR1 vs. Ensembl Human
Match: STK26 (serine/threonine kinase 26 [Source:HGNC Symbol;Acc:HGNC:18174]) HSP 1 Score: 197.978 bits (502), Expect = 5.866e-57 Identity = 113/293 (38.57%), Postives = 171/293 (58.36%), Query Frame = 2
Query: 185 IGQGATSNVYEAECLPLNNR---LCAMKIINLEKCNSSSLLEEIKREIKSMKNMKNENIVTYYASFVNGIELFIIMDVCQRGSLLDIIKRTQSKRDITYGVFDESTIATILKDVLRGLTYIHENGLVHRDLKCGNLLVKDDGIIQIADFGVAAFLAAQPMHTTGASLDNKRFTFVGTPCWMAPEVMQQVKGHNQKADIWSLGITAIELAAGQAPYAKYAPMKVLMLTLQNESPDIDTAASSCNQYSNYGQKYRKFSKACLNKDPAMRPSAKELLQSPFIKSKAKDRDSLIKVL 1054
IG+G+ V++ ++NR + A+KII+LE+ + +EI + + + YY S++ G +L+IIM+ GS LD+++ G FDE IAT+LK++L+GL Y+H +HRD+K N+L+ + G +++ADFGVA L + KR TFVGTP WMAPEV+QQ ++ KADIWSLGITAIELA G+ P + PM+VL L +N P + ++ + +++F ACLNKDP+ RP+AKELL+ FI +K L +++
Sbjct: 30 IGKGSFGEVFKG----IDNRTQQVVAIKIIDLEEAEDEIEDIQ--QEITVLSQCDSSYVTKYYGSYLKGSKLWIIMEYLGGGSALDLLRA---------GPFDEFQIATMLKEILKGLDYLHSEKKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQI---------KRNTFVGTPFWMAPEVIQQ-SAYDSKADIWSLGITAIELAKGEPPNSDMHPMRVLFLIPKNNPPTL---------VGDFTKSFKEFIDACLNKDPSFRPTAKELLKHKFIVKNSKKTSYLTELI 288
BLAST of Serine/threonine-protein kinase OSR1 vs. Ensembl Human
Match: STK26 (serine/threonine kinase 26 [Source:HGNC Symbol;Acc:HGNC:18174]) HSP 1 Score: 198.364 bits (503), Expect = 1.002e-56 Identity = 113/293 (38.57%), Postives = 171/293 (58.36%), Query Frame = 2
Query: 185 IGQGATSNVYEAECLPLNNR---LCAMKIINLEKCNSSSLLEEIKREIKSMKNMKNENIVTYYASFVNGIELFIIMDVCQRGSLLDIIKRTQSKRDITYGVFDESTIATILKDVLRGLTYIHENGLVHRDLKCGNLLVKDDGIIQIADFGVAAFLAAQPMHTTGASLDNKRFTFVGTPCWMAPEVMQQVKGHNQKADIWSLGITAIELAAGQAPYAKYAPMKVLMLTLQNESPDIDTAASSCNQYSNYGQKYRKFSKACLNKDPAMRPSAKELLQSPFIKSKAKDRDSLIKVL 1054
IG+G+ V++ ++NR + A+KII+LE+ + +EI + + + YY S++ G +L+IIM+ GS LD+++ G FDE IAT+LK++L+GL Y+H +HRD+K N+L+ + G +++ADFGVA L + KR TFVGTP WMAPEV+QQ ++ KADIWSLGITAIELA G+ P + PM+VL L +N P + ++ + +++F ACLNKDP+ RP+AKELL+ FI +K L +++
Sbjct: 30 IGKGSFGEVFKG----IDNRTQQVVAIKIIDLEEAEDEIEDIQ--QEITVLSQCDSSYVTKYYGSYLKGSKLWIIMEYLGGGSALDLLRA---------GPFDEFQIATMLKEILKGLDYLHSEKKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQI---------KRNTFVGTPFWMAPEVIQQ-SAYDSKADIWSLGITAIELAKGEPPNSDMHPMRVLFLIPKNNPPTL---------VGDFTKSFKEFIDACLNKDPSFRPTAKELLKHKFIVKNSKKTSYLTELI 288
BLAST of Serine/threonine-protein kinase OSR1 vs. Ensembl Celegans
Match: gck-3 (Germinal center kinase 3 [Source:UniProtKB/Swiss-Prot;Acc:G5EEN4]) HSP 1 Score: 323.168 bits (827), Expect = 2.729e-103 Identity = 165/343 (48.10%), Postives = 226/343 (65.89%), Query Frame = 2
Query: 146 WSNKREDYKINRSIGQGATSNVYEAECLPLNNRLCAMKIINLEKCNSSSLLEEIKREIKSMKNMKNENIVTYYASFVNGIELFIIMDVCQRGSLLDIIKR---TQSKRDITYGVFDESTIATILKDVLRGLTYIHENGLVHRDLKCGNLLVKDDGIIQIADFGVAAFLAAQPMHTTGASLDNK--RFTFVGTPCWMAPEVMQQVKGHNQKADIWSLGITAIELAAGQAPYAKYAPMKVLMLTLQNESPDIDTAASSCNQYSNYGQKYRKFSKACLNKDPAMRPSAKELLQSPFIKSKAKDRDSLIKVLLSE-DTLPFERQRSDENLCPEKTPTKAFSGEWNFD 1156
W + YK++ SIG GAT+ V+ A CLP N ++ A+K INLEKC +S ++E+ EI++M + N+V+YY SF+ EL+++M + GS+LDI+KR K +GV DE +IAT+L++VL+GL Y H NG +HRD+K GN+L+ DDG IQIADFGV+ +LA ++G L + R TFVGTPCWMAPEVM+QV+G++ KADIWSLGI AIELA G APY KY PMKVLMLTLQN+ P ++T A +QY YG+ ++ + CL KDPA RP+A ELL+ F K K KD+ L+ L+ ++P S + + K A G W F+
Sbjct: 101 WPTEPSAYKLDESIGVGATATVFTAYCLPRNEKV-AIKCINLEKCQTS--VDELSHEIQAMSQCNHPNVVSYYTSFIAQEELWVVMRLLNCGSMLDILKRKVKAIGKEQAQFGVLDEVSIATVLREVLKGLEYFHLNGQIHRDIKAGNILLADDGTIQIADFGVSGWLA-----SSGGDLSRQKVRHTFVGTPCWMAPEVMEQVQGYDFKADIWSLGILAIELATGTAPYHKYPPMKVLMLTLQNDPPTLETNAERKDQYKAYGKSFKTLIRDCLQKDPAKRPTASELLKYSFFK-KGKDKKYLVHTLIENLASVPVVAHHSSKKVASGKLRKDAH-GNWEFE 433
BLAST of Serine/threonine-protein kinase OSR1 vs. Ensembl Celegans
Match: gck-3 (Germinal center kinase 3 [Source:UniProtKB/Swiss-Prot;Acc:G5EEN4]) HSP 1 Score: 324.324 bits (830), Expect = 4.999e-103 Identity = 165/343 (48.10%), Postives = 226/343 (65.89%), Query Frame = 2
Query: 146 WSNKREDYKINRSIGQGATSNVYEAECLPLNNRLCAMKIINLEKCNSSSLLEEIKREIKSMKNMKNENIVTYYASFVNGIELFIIMDVCQRGSLLDIIKR---TQSKRDITYGVFDESTIATILKDVLRGLTYIHENGLVHRDLKCGNLLVKDDGIIQIADFGVAAFLAAQPMHTTGASLDNK--RFTFVGTPCWMAPEVMQQVKGHNQKADIWSLGITAIELAAGQAPYAKYAPMKVLMLTLQNESPDIDTAASSCNQYSNYGQKYRKFSKACLNKDPAMRPSAKELLQSPFIKSKAKDRDSLIKVLLSE-DTLPFERQRSDENLCPEKTPTKAFSGEWNFD 1156
W + YK++ SIG GAT+ V+ A CLP N ++ A+K INLEKC +S ++E+ EI++M + N+V+YY SF+ EL+++M + GS+LDI+KR K +GV DE +IAT+L++VL+GL Y H NG +HRD+K GN+L+ DDG IQIADFGV+ +LA ++G L + R TFVGTPCWMAPEVM+QV+G++ KADIWSLGI AIELA G APY KY PMKVLMLTLQN+ P ++T A +QY YG+ ++ + CL KDPA RP+A ELL+ F K K KD+ L+ L+ ++P S + + K A G W F+
Sbjct: 101 WPTEPSAYKLDESIGVGATATVFTAYCLPRNEKV-AIKCINLEKCQTS--VDELSHEIQAMSQCNHPNVVSYYTSFIAQEELWVVMRLLNCGSMLDILKRKVKAIGKEQAQFGVLDEVSIATVLREVLKGLEYFHLNGQIHRDIKAGNILLADDGTIQIADFGVSGWLA-----SSGGDLSRQKVRHTFVGTPCWMAPEVMEQVQGYDFKADIWSLGILAIELATGTAPYHKYPPMKVLMLTLQNDPPTLETNAERKDQYKAYGKSFKTLIRDCLQKDPAKRPTASELLKYSFFK-KGKDKKYLVHTLIENLASVPVVAHHSSKKVASGKLRKDAH-GNWEFE 433 HSP 2 Score: 59.6918 bits (143), Expect = 3.624e-9 Identity = 38/101 (37.62%), Postives = 59/101 (58.42%), Query Frame = 2
Query: 1244 PISYRITLRKRNPKKNNELEDISFDYVIGKDSVELLVRELVEADLLDGCDLLLVAHNMSELV----ANPSVRERVFALNSP-PSTGVANEQELYGYAKVLL 1531
P + + LR RN ++ EL DI FDY D+VE + ELV A+L+D DL++VA N+ +L+ + R FALNS + + +E+ L G+A++ L
Sbjct: 496 PETLNMVLRVRNQQR--ELNDIKFDYTKSADTVEGIAHELVTAELIDCHDLVIVAANLQKLIDFAESKSDRRSITFALNSGVHANEIPDERTLTGFAQISL 594
BLAST of Serine/threonine-protein kinase OSR1 vs. Ensembl Celegans
Match: gck-3 (Germinal center kinase 3 [Source:UniProtKB/Swiss-Prot;Acc:G5EEN4]) HSP 1 Score: 273.092 bits (697), Expect = 3.239e-85 Identity = 138/283 (48.76%), Postives = 185/283 (65.37%), Query Frame = 2
Query: 326 MKNMKNENIVTYYASFVNGIELFIIMDVCQRGSLLDIIKR---TQSKRDITYGVFDESTIATILKDVLRGLTYIHENGLVHRDLKCGNLLVKDDGIIQIADFGVAAFLAAQPMHTTGASLDNK--RFTFVGTPCWMAPEVMQQVKGHNQKADIWSLGITAIELAAGQAPYAKYAPMKVLMLTLQNESPDIDTAASSCNQYSNYGQKYRKFSKACLNKDPAMRPSAKELLQSPFIKSKAKDRDSLIKVLLSE-DTLPFERQRSDENLCPEKTPTKAFSGEWNFD 1156
M + N+V+YY SF+ EL+++M + GS+LDI+KR K +GV DE +IAT+L++VL+GL Y H NG +HRD+K GN+L+ DDG IQIADFGV+ +LA ++G L + R TFVGTPCWMAPEVM+QV+G++ KADIWSLGI AIELA G APY KY PMKVLMLTLQN+ P ++T A +QY YG+ ++ + CL KDPA RP+A ELL+ F K K KD+ L+ L+ ++P S + + K A G W F+
Sbjct: 1 MSQCNHPNVVSYYTSFIAQEELWVVMRLLNCGSMLDILKRKVKAIGKEQAQFGVLDEVSIATVLREVLKGLEYFHLNGQIHRDIKAGNILLADDGTIQIADFGVSGWLA-----SSGGDLSRQKVRHTFVGTPCWMAPEVMEQVQGYDFKADIWSLGILAIELATGTAPYHKYPPMKVLMLTLQNDPPTLETNAERKDQYKAYGKSFKTLIRDCLQKDPAKRPTASELLKYSFFK-KGKDKKYLVHTLIENLASVPVVAHHSSKKVASGKLRKDA-HGNWEFE 276 HSP 2 Score: 59.6918 bits (143), Expect = 3.343e-9 Identity = 38/101 (37.62%), Postives = 59/101 (58.42%), Query Frame = 2
Query: 1244 PISYRITLRKRNPKKNNELEDISFDYVIGKDSVELLVRELVEADLLDGCDLLLVAHNMSELV----ANPSVRERVFALNSP-PSTGVANEQELYGYAKVLL 1531
P + + LR RN ++ EL DI FDY D+VE + ELV A+L+D DL++VA N+ +L+ + R FALNS + + +E+ L G+A++ L
Sbjct: 339 PETLNMVLRVRNQQR--ELNDIKFDYTKSADTVEGIAHELVTAELIDCHDLVIVAANLQKLIDFAESKSDRRSITFALNSGVHANEIPDERTLTGFAQISL 437
BLAST of Serine/threonine-protein kinase OSR1 vs. Ensembl Celegans
Match: gck-1 (Germinal center kinase 1 [Source:UniProtKB/Swiss-Prot;Acc:H2L099]) HSP 1 Score: 206.453 bits (524), Expect = 2.740e-58 Identity = 116/293 (39.59%), Postives = 175/293 (59.73%), Query Frame = 2
Query: 185 IGQGATSNVYEAECLPLNNR---LCAMKIINLEKCNSSSLLEEIKREIKSMKNMKNENIVTYYASFVNGIELFIIMDVCQRGSLLDIIKRTQSKRDITYGVFDESTIATILKDVLRGLTYIHENGLVHRDLKCGNLLVKDDGIIQIADFGVAAFLAAQPMHTTGASLDNKRFTFVGTPCWMAPEVMQQVKGHNQKADIWSLGITAIELAAGQAPYAKYAPMKVLMLTLQNESPDIDTAASSCNQYSNYGQKYRKFSKACLNKDPAMRPSAKELLQSPFIKSKAKDRDSLIKVL 1054
IG+G+ VY+ ++NR + A+KII+LE+ +E+I++EI+ + ++ + Y+ SF+ G +L+IIM+ GS LD+ K G DES IA IL+++L+GL Y+H +HRD+K N+LV + G +++ADFGVA L KR TFVG+P WMAPE+++Q ++ KADIWSLGITAIELA G+ P++ PM+VL L +N P + Q S + + +++F + CLNKDP RPSA LL+ FIK +AK L+ ++
Sbjct: 20 IGRGSFGEVYKG----IDNRTGRVVAIKIIDLEQAEDE--IEDIQQEIQVLSQCDSQYVTKYFGSFLKGSKLWIIMEYLGGGSALDLTKS---------GKLDESHIAVILREILKGLEYLHSERKIHRDIKAANVLVSEHGDVKVADFGVAGQL---------TETVKKRITFVGSPFWMAPELIKQ-SSYDYKADIWSLGITAIELANGEPPHSDLHPMRVLFLIPKNPPPVL--------QGSQWSKPFKEFVEMCLNKDPENRPSASTLLKHQFIK-RAKKNSILVDLI 278
BLAST of Serine/threonine-protein kinase OSR1 vs. Ensembl Celegans
Match: gck-1 (Germinal center kinase 1 [Source:UniProtKB/Swiss-Prot;Acc:H2L099]) HSP 1 Score: 206.453 bits (524), Expect = 2.829e-58 Identity = 116/293 (39.59%), Postives = 175/293 (59.73%), Query Frame = 2
Query: 185 IGQGATSNVYEAECLPLNNR---LCAMKIINLEKCNSSSLLEEIKREIKSMKNMKNENIVTYYASFVNGIELFIIMDVCQRGSLLDIIKRTQSKRDITYGVFDESTIATILKDVLRGLTYIHENGLVHRDLKCGNLLVKDDGIIQIADFGVAAFLAAQPMHTTGASLDNKRFTFVGTPCWMAPEVMQQVKGHNQKADIWSLGITAIELAAGQAPYAKYAPMKVLMLTLQNESPDIDTAASSCNQYSNYGQKYRKFSKACLNKDPAMRPSAKELLQSPFIKSKAKDRDSLIKVL 1054
IG+G+ VY+ ++NR + A+KII+LE+ +E+I++EI+ + ++ + Y+ SF+ G +L+IIM+ GS LD+ K G DES IA IL+++L+GL Y+H +HRD+K N+LV + G +++ADFGVA L KR TFVG+P WMAPE+++Q ++ KADIWSLGITAIELA G+ P++ PM+VL L +N P + Q S + + +++F + CLNKDP RPSA LL+ FIK +AK L+ ++
Sbjct: 25 IGRGSFGEVYKG----IDNRTGRVVAIKIIDLEQAEDE--IEDIQQEIQVLSQCDSQYVTKYFGSFLKGSKLWIIMEYLGGGSALDLTKS---------GKLDESHIAVILREILKGLEYLHSERKIHRDIKAANVLVSEHGDVKVADFGVAGQL---------TETVKKRITFVGSPFWMAPELIKQ-SSYDYKADIWSLGITAIELANGEPPHSDLHPMRVLFLIPKNPPPVL--------QGSQWSKPFKEFVEMCLNKDPENRPSASTLLKHQFIK-RAKKNSILVDLI 283
BLAST of Serine/threonine-protein kinase OSR1 vs. Ensembl Fly
Match: fray (gene:FBgn0023083 transcript:FBtr0083638) HSP 1 Score: 335.495 bits (859), Expect = 8.592e-108 Identity = 166/307 (54.07%), Postives = 218/307 (71.01%), Query Frame = 2
Query: 143 VWSNKREDYKINRSIGQGATSNVYEAECLPLNNRLCAMKIINLEKCNSSSLLEEIKREIKSMKNMKNENIVTYYASFVNGIELFIIMDVCQRGSLLDIIKRTQSKRDITYGVFDESTIATILKDVLRGLTYIHENGLVHRDLKCGNLLVKDDGIIQIADFGVAAFLAAQPMHTTGASLDNK--RFTFVGTPCWMAPEVMQQVKGHNQKADIWSLGITAIELAAGQAPYAKYAPMKVLMLTLQNESPDIDTAASSCNQYSNYGQKYRKFSKACLNKDPAMRPSAKELLQSPFIKSKAKDRDSLIKVLL 1057
W N ++DY++ IG GAT+ V+ A C+P N + CA+K INLEK N+S ++E+ +EI++M + +EN+VTY+ SFV EL++++ + + GSLLDIIK + GVFDE+TIAT+LK+VL+GL Y H NG +HRD+K GN+L+ DDG IQIADFGV+A+LA TG L + R TFVGTPCWMAPEVM+Q G++ KADIWS GITAIE+A G APY KY PMKVLMLTLQN+ P +DT A +QY YG+ +RK CL K+P+ RP+A ELL+ F K KAKDR L + LL
Sbjct: 30 TWPNSKDDYELRDVIGVGATAVVHGAYCIPRNEK-CAIKRINLEKWNTS--MDELLKEIQAMSSCFHENVVTYHTSFVVREELWLVLRLLEGGSLLDIIKHKMRTSNCKQGVFDEATIATVLKEVLKGLEYFHSNGQIHRDIKAGNILIGDDGTIQIADFGVSAWLA------TGRDLSRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGITAIEMATGTAPYHKYPPMKVLMLTLQNDPPTLDTGADDKDQYKAYGKTFRKMIVECLQKEPSKRPTASELLKHAFFK-KAKDRKYLTQTLL 326 HSP 2 Score: 59.3066 bits (142), Expect = 7.099e-9 Identity = 34/91 (37.36%), Postives = 58/91 (63.74%), Query Frame = 2
Query: 1259 ITLRKRNPKKNNELEDISFDYVIGKDSVELLVRELVEADLLDGCDLLLVAHNMSELV-ANPSVRERVFALNSPPSTG-VANEQELYGYAKV 1525
+ LR RN ++ EL DI F++V+GKD+ E + ELV+A L+D D +A ++ +L+ A+ +++ F L+S G V +E+ L GYA++
Sbjct: 460 LVLRMRNLRR--ELHDIRFEFVVGKDTAEGIATELVDAGLVDALDTQPMATHLDQLIAASATMKTITFQLSSGVQPGEVPDERSLVGYAQI 548
BLAST of Serine/threonine-protein kinase OSR1 vs. Ensembl Fly
Match: fray (gene:FBgn0023083 transcript:FBtr0347418) HSP 1 Score: 335.495 bits (859), Expect = 8.592e-108 Identity = 166/307 (54.07%), Postives = 218/307 (71.01%), Query Frame = 2
Query: 143 VWSNKREDYKINRSIGQGATSNVYEAECLPLNNRLCAMKIINLEKCNSSSLLEEIKREIKSMKNMKNENIVTYYASFVNGIELFIIMDVCQRGSLLDIIKRTQSKRDITYGVFDESTIATILKDVLRGLTYIHENGLVHRDLKCGNLLVKDDGIIQIADFGVAAFLAAQPMHTTGASLDNK--RFTFVGTPCWMAPEVMQQVKGHNQKADIWSLGITAIELAAGQAPYAKYAPMKVLMLTLQNESPDIDTAASSCNQYSNYGQKYRKFSKACLNKDPAMRPSAKELLQSPFIKSKAKDRDSLIKVLL 1057
W N ++DY++ IG GAT+ V+ A C+P N + CA+K INLEK N+S ++E+ +EI++M + +EN+VTY+ SFV EL++++ + + GSLLDIIK + GVFDE+TIAT+LK+VL+GL Y H NG +HRD+K GN+L+ DDG IQIADFGV+A+LA TG L + R TFVGTPCWMAPEVM+Q G++ KADIWS GITAIE+A G APY KY PMKVLMLTLQN+ P +DT A +QY YG+ +RK CL K+P+ RP+A ELL+ F K KAKDR L + LL
Sbjct: 30 TWPNSKDDYELRDVIGVGATAVVHGAYCIPRNEK-CAIKRINLEKWNTS--MDELLKEIQAMSSCFHENVVTYHTSFVVREELWLVLRLLEGGSLLDIIKHKMRTSNCKQGVFDEATIATVLKEVLKGLEYFHSNGQIHRDIKAGNILIGDDGTIQIADFGVSAWLA------TGRDLSRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGITAIEMATGTAPYHKYPPMKVLMLTLQNDPPTLDTGADDKDQYKAYGKTFRKMIVECLQKEPSKRPTASELLKHAFFK-KAKDRKYLTQTLL 326 HSP 2 Score: 59.3066 bits (142), Expect = 7.099e-9 Identity = 34/91 (37.36%), Postives = 58/91 (63.74%), Query Frame = 2
Query: 1259 ITLRKRNPKKNNELEDISFDYVIGKDSVELLVRELVEADLLDGCDLLLVAHNMSELV-ANPSVRERVFALNSPPSTG-VANEQELYGYAKV 1525
+ LR RN ++ EL DI F++V+GKD+ E + ELV+A L+D D +A ++ +L+ A+ +++ F L+S G V +E+ L GYA++
Sbjct: 460 LVLRMRNLRR--ELHDIRFEFVVGKDTAEGIATELVDAGLVDALDTQPMATHLDQLIAASATMKTITFQLSSGVQPGEVPDERSLVGYAQI 548
BLAST of Serine/threonine-protein kinase OSR1 vs. Ensembl Fly
Match: fray (gene:FBgn0023083 transcript:FBtr0290210) HSP 1 Score: 335.495 bits (859), Expect = 8.592e-108 Identity = 166/307 (54.07%), Postives = 218/307 (71.01%), Query Frame = 2
Query: 143 VWSNKREDYKINRSIGQGATSNVYEAECLPLNNRLCAMKIINLEKCNSSSLLEEIKREIKSMKNMKNENIVTYYASFVNGIELFIIMDVCQRGSLLDIIKRTQSKRDITYGVFDESTIATILKDVLRGLTYIHENGLVHRDLKCGNLLVKDDGIIQIADFGVAAFLAAQPMHTTGASLDNK--RFTFVGTPCWMAPEVMQQVKGHNQKADIWSLGITAIELAAGQAPYAKYAPMKVLMLTLQNESPDIDTAASSCNQYSNYGQKYRKFSKACLNKDPAMRPSAKELLQSPFIKSKAKDRDSLIKVLL 1057
W N ++DY++ IG GAT+ V+ A C+P N + CA+K INLEK N+S ++E+ +EI++M + +EN+VTY+ SFV EL++++ + + GSLLDIIK + GVFDE+TIAT+LK+VL+GL Y H NG +HRD+K GN+L+ DDG IQIADFGV+A+LA TG L + R TFVGTPCWMAPEVM+Q G++ KADIWS GITAIE+A G APY KY PMKVLMLTLQN+ P +DT A +QY YG+ +RK CL K+P+ RP+A ELL+ F K KAKDR L + LL
Sbjct: 30 TWPNSKDDYELRDVIGVGATAVVHGAYCIPRNEK-CAIKRINLEKWNTS--MDELLKEIQAMSSCFHENVVTYHTSFVVREELWLVLRLLEGGSLLDIIKHKMRTSNCKQGVFDEATIATVLKEVLKGLEYFHSNGQIHRDIKAGNILIGDDGTIQIADFGVSAWLA------TGRDLSRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGITAIEMATGTAPYHKYPPMKVLMLTLQNDPPTLDTGADDKDQYKAYGKTFRKMIVECLQKEPSKRPTASELLKHAFFK-KAKDRKYLTQTLL 326 HSP 2 Score: 59.3066 bits (142), Expect = 7.099e-9 Identity = 34/91 (37.36%), Postives = 58/91 (63.74%), Query Frame = 2
Query: 1259 ITLRKRNPKKNNELEDISFDYVIGKDSVELLVRELVEADLLDGCDLLLVAHNMSELV-ANPSVRERVFALNSPPSTG-VANEQELYGYAKV 1525
+ LR RN ++ EL DI F++V+GKD+ E + ELV+A L+D D +A ++ +L+ A+ +++ F L+S G V +E+ L GYA++
Sbjct: 460 LVLRMRNLRR--ELHDIRFEFVVGKDTAEGIATELVDAGLVDALDTQPMATHLDQLIAASATMKTITFQLSSGVQPGEVPDERSLVGYAQI 548
BLAST of Serine/threonine-protein kinase OSR1 vs. Ensembl Fly
Match: fray (gene:FBgn0023083 transcript:FBtr0290107) HSP 1 Score: 335.495 bits (859), Expect = 8.592e-108 Identity = 166/307 (54.07%), Postives = 218/307 (71.01%), Query Frame = 2
Query: 143 VWSNKREDYKINRSIGQGATSNVYEAECLPLNNRLCAMKIINLEKCNSSSLLEEIKREIKSMKNMKNENIVTYYASFVNGIELFIIMDVCQRGSLLDIIKRTQSKRDITYGVFDESTIATILKDVLRGLTYIHENGLVHRDLKCGNLLVKDDGIIQIADFGVAAFLAAQPMHTTGASLDNK--RFTFVGTPCWMAPEVMQQVKGHNQKADIWSLGITAIELAAGQAPYAKYAPMKVLMLTLQNESPDIDTAASSCNQYSNYGQKYRKFSKACLNKDPAMRPSAKELLQSPFIKSKAKDRDSLIKVLL 1057
W N ++DY++ IG GAT+ V+ A C+P N + CA+K INLEK N+S ++E+ +EI++M + +EN+VTY+ SFV EL++++ + + GSLLDIIK + GVFDE+TIAT+LK+VL+GL Y H NG +HRD+K GN+L+ DDG IQIADFGV+A+LA TG L + R TFVGTPCWMAPEVM+Q G++ KADIWS GITAIE+A G APY KY PMKVLMLTLQN+ P +DT A +QY YG+ +RK CL K+P+ RP+A ELL+ F K KAKDR L + LL
Sbjct: 30 TWPNSKDDYELRDVIGVGATAVVHGAYCIPRNEK-CAIKRINLEKWNTS--MDELLKEIQAMSSCFHENVVTYHTSFVVREELWLVLRLLEGGSLLDIIKHKMRTSNCKQGVFDEATIATVLKEVLKGLEYFHSNGQIHRDIKAGNILIGDDGTIQIADFGVSAWLA------TGRDLSRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGITAIEMATGTAPYHKYPPMKVLMLTLQNDPPTLDTGADDKDQYKAYGKTFRKMIVECLQKEPSKRPTASELLKHAFFK-KAKDRKYLTQTLL 326 HSP 2 Score: 59.3066 bits (142), Expect = 7.099e-9 Identity = 34/91 (37.36%), Postives = 58/91 (63.74%), Query Frame = 2
Query: 1259 ITLRKRNPKKNNELEDISFDYVIGKDSVELLVRELVEADLLDGCDLLLVAHNMSELV-ANPSVRERVFALNSPPSTG-VANEQELYGYAKV 1525
+ LR RN ++ EL DI F++V+GKD+ E + ELV+A L+D D +A ++ +L+ A+ +++ F L+S G V +E+ L GYA++
Sbjct: 460 LVLRMRNLRR--ELHDIRFEFVVGKDTAEGIATELVDAGLVDALDTQPMATHLDQLIAASATMKTITFQLSSGVQPGEVPDERSLVGYAQI 548
BLAST of Serine/threonine-protein kinase OSR1 vs. Ensembl Fly
Match: fray (gene:FBgn0023083 transcript:FBtr0347417) HSP 1 Score: 335.495 bits (859), Expect = 8.592e-108 Identity = 166/307 (54.07%), Postives = 218/307 (71.01%), Query Frame = 2
Query: 143 VWSNKREDYKINRSIGQGATSNVYEAECLPLNNRLCAMKIINLEKCNSSSLLEEIKREIKSMKNMKNENIVTYYASFVNGIELFIIMDVCQRGSLLDIIKRTQSKRDITYGVFDESTIATILKDVLRGLTYIHENGLVHRDLKCGNLLVKDDGIIQIADFGVAAFLAAQPMHTTGASLDNK--RFTFVGTPCWMAPEVMQQVKGHNQKADIWSLGITAIELAAGQAPYAKYAPMKVLMLTLQNESPDIDTAASSCNQYSNYGQKYRKFSKACLNKDPAMRPSAKELLQSPFIKSKAKDRDSLIKVLL 1057
W N ++DY++ IG GAT+ V+ A C+P N + CA+K INLEK N+S ++E+ +EI++M + +EN+VTY+ SFV EL++++ + + GSLLDIIK + GVFDE+TIAT+LK+VL+GL Y H NG +HRD+K GN+L+ DDG IQIADFGV+A+LA TG L + R TFVGTPCWMAPEVM+Q G++ KADIWS GITAIE+A G APY KY PMKVLMLTLQN+ P +DT A +QY YG+ +RK CL K+P+ RP+A ELL+ F K KAKDR L + LL
Sbjct: 30 TWPNSKDDYELRDVIGVGATAVVHGAYCIPRNEK-CAIKRINLEKWNTS--MDELLKEIQAMSSCFHENVVTYHTSFVVREELWLVLRLLEGGSLLDIIKHKMRTSNCKQGVFDEATIATVLKEVLKGLEYFHSNGQIHRDIKAGNILIGDDGTIQIADFGVSAWLA------TGRDLSRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGITAIEMATGTAPYHKYPPMKVLMLTLQNDPPTLDTGADDKDQYKAYGKTFRKMIVECLQKEPSKRPTASELLKHAFFK-KAKDRKYLTQTLL 326 HSP 2 Score: 59.3066 bits (142), Expect = 7.099e-9 Identity = 34/91 (37.36%), Postives = 58/91 (63.74%), Query Frame = 2
Query: 1259 ITLRKRNPKKNNELEDISFDYVIGKDSVELLVRELVEADLLDGCDLLLVAHNMSELV-ANPSVRERVFALNSPPSTG-VANEQELYGYAKV 1525
+ LR RN ++ EL DI F++V+GKD+ E + ELV+A L+D D +A ++ +L+ A+ +++ F L+S G V +E+ L GYA++
Sbjct: 460 LVLRMRNLRR--ELHDIRFEFVVGKDTAEGIATELVDAGLVDALDTQPMATHLDQLIAASATMKTITFQLSSGVQPGEVPDERSLVGYAQI 548
BLAST of Serine/threonine-protein kinase OSR1 vs. Ensembl Zebrafish
Match: oxsr1a (oxidative stress responsive kinase 1a [Source:ZFIN;Acc:ZDB-GENE-070620-25]) HSP 1 Score: 348.206 bits (892), Expect = 4.334e-113 Identity = 212/514 (41.25%), Postives = 299/514 (58.17%), Query Frame = 2
Query: 146 WSNKREDYKINRSIGQGATSNVYEAECLPLNNRLCAMKIINLEKCNSSSLLEEIKREIKSMKNMKNENIVTYYASFVNGIELFIIMDVCQRGSLLDIIKRTQSKRDITYGVFDESTIATILKDVLRGLTYIHENGLVHRDLKCGNLLVKDDGIIQIADFGVAAFLAAQPMHTTGASLDNK-RFTFVGTPCWMAPEVMQQVKGHNQKADIWSLGITAIELAAGQAPYAKYAPMKVLMLTLQNESPDIDTAASSCNQYSNYGQKYRKFSKACLNKDPAMRPSAKELLQSPFIKSKAKDRDSLIKVLLSEDTLPFERQR----------------------SDENLCPEKTPTKA--------------------FSGEWNFDLQPLGDHLNDI----DNKESVDKTE-----NETFENSEPISYRITLRKRNPKKNNELEDISFDYVIGKDSVELLVRELVEADLLDGCDLLLVAHNMSELVANPSVRERV-FALNSP-PSTGVANEQELYGYAKV 1525
WS ++DY++ IG GAT+ V A C P ++ A+K INLEKC +S ++E+ +EI++M + NIV+YY SFV EL+++M + GS+LD IK SK + GV DE +IATIL++VL GL Y+H+NG +HRD+K GN+L+ +DG +QIADFGV+AFLA T G NK R TFVGTPCWMAPEVM+QV+G++ KAD+WS GITAIELA G APY KY PMKVLMLTLQN+ P ++T + YG+ +RK CL KDP RP+A ELL+ F +KAK+ D L + LL ER R SD+ L E KA F E + LQP ++ D+ ++ ++ T ++S I + LR RN KK EL DI F+++ G+D+ + + +ELV A L+DG DL++VA N+ ++V +P + V F L S S+ + ++ +L G+A++
Sbjct: 10 WSIDKDDYELQEVIGSGATAVVQAAYCKPRKEKV-AIKRINLEKCQTS--MDELLKEIQAMSQCHHPNIVSYYTSFVVKDELWLVMKLLSGGSVLDFIKYIISKGEHKSGVMDEPSIATILREVLEGLEYLHKNGQIHRDVKAGNILLGEDGSVQIADFGVSAFLA-----TGGDMTRNKVRKTFVGTPCWMAPEVMEQVRGYDFKADLWSFGITAIELATGAAPYHKYPPMKVLMLTLQNDPPCLETGVTDKEMVKKYGKSFRKMISLCLQKDPEKRPTAAELLKHKFF-TKAKNTDYLKEKLLERAPTIGERSRKVRRVPGSSGRLHKTEDGEWEWSDDELDVESEEGKAAVAALRSPRVKEEAVPNAEVFPAESSGFLQPAAVGQPEVPHAADDTATISASQAVAGPTTTGQDSAKIPISLVLRLRNTKK--ELNDIRFEFMPGRDTADGVSQELVSAGLVDGRDLVIVAANLQKIVDDPQTHKNVTFKLASGVDSSEIPDDVKLMGFAQL 512
BLAST of Serine/threonine-protein kinase OSR1 vs. Ensembl Zebrafish
Match: oxsr1b (oxidative stress responsive kinase 1b [Source:ZFIN;Acc:ZDB-GENE-040426-723]) HSP 1 Score: 345.51 bits (885), Expect = 5.398e-112 Identity = 212/522 (40.61%), Postives = 296/522 (56.70%), Query Frame = 2
Query: 146 WSNKREDYKINRSIGQGATSNVYEAECLPLNNRLCAMKIINLEKCNSSSLLEEIKREIKSMKNMKNENIVTYYASFVNGIELFIIMDVCQRGSLLDIIKRTQSKRDITYGVFDESTIATILKDVLRGLTYIHENGLVHRDLKCGNLLVKDDGIIQIADFGVAAFLAAQPMHTTGASLDNK-RFTFVGTPCWMAPEVMQQVKGHNQKADIWSLGITAIELAAGQAPYAKYAPMKVLMLTLQNESPDIDTAASSCNQYSNYGQKYRKFSKACLNKDPAMRPSAKELLQSPFIKSKAKDRDSLIKVLLSEDTLPFERQRSDENLCPEKTPT--KAFSGEWNFD-------------------------------LQPLGDHL---------NDIDNKESVDKTENETFENS-----------------EPISYRITLRKRNPKKNNELEDISFDYVIGKDSVELLVRELVEADLLDGCDLLLVAHNMSELVANPSVRERV-FALNSP-PSTGVANEQELYGYAKV 1525
WS ++DY++ IG GAT+ V A C+P ++ A+K INLEKC +S ++E+ +EI++M + NIV+YY SFV EL+++M + GS+LD+IK SK + GV DE +IAT+LK+VL+GL Y+H+NG +HRDLK GN+L+ +DG +QIADFGV+AFLA T G NK R TFVGTPCWMAPEVM+QVKG++ KADIWS GITAIELA G APY KY PMKVLMLTLQN+ P ++T + YG+ RK CL K+P RP++ ELL+ F + KAK+ + L + LL ER R + P + K GEW + QP G HL N ++ +T + S PIS + LR RN KK EL DI F+++ G+D+ + + +ELV A L+DG DL++VA N+ ++V P + V F L S + + ++ +L G+A++
Sbjct: 10 WSINKDDYELQEVIGSGATAVVQAAYCVPRKEKV-AIKRINLEKCQTS--MDELLKEIQAMSQCHHPNIVSYYTSFVVKDELWLVMKLLSGGSVLDVIKHIISKGEHKTGVLDEPSIATVLKEVLQGLEYLHKNGQIHRDLKAGNILLGEDGSVQIADFGVSAFLA-----TGGDMTRNKVRKTFVGTPCWMAPEVMEQVKGYDFKADIWSFGITAIELATGAAPYHKYPPMKVLMLTLQNDPPCLETGITDKEMVKKYGKSLRKMISQCLQKEPEKRPTSSELLKHKFFQ-KAKNNEFLQEKLLHRAPTITERARKVRRV-PGSSGRLHKTEDGEWEWSDDELDEESEEGKAAVAALRSPRVKEGENAEVFQPFGSHLQPELPQAAGQSPANTQNTGQTTGSSQAQSTAPNPTQASVPGGDASQSPIS--LVLRLRNLKK--ELNDIRFEFMPGRDTADGVSQELVSAGLVDGKDLVIVAANLQKIVEEPHSNKNVTFKLASGVEGSEIPDDNKLLGFAQL 517
BLAST of Serine/threonine-protein kinase OSR1 vs. Ensembl Zebrafish
Match: stk39 (serine threonine kinase 39 [Source:ZFIN;Acc:ZDB-GENE-140106-194]) HSP 1 Score: 343.969 bits (881), Expect = 3.376e-111 Identity = 207/482 (42.95%), Postives = 290/482 (60.17%), Query Frame = 2
Query: 104 SDSNAVDGSNQ---TIVWSNKREDYKINRSIGQGATSNVYEAECLPLNNRLCAMKIINLEKCNSSSLLEEIKREIKSMKNMKNENIVTYYASFVNGIELFIIMDVCQRGSLLDIIKRTQSKRDITYGVFDESTIATILKDVLRGLTYIHENGLVHRDLKCGNLLVKDDGIIQIADFGVAAFLAAQPMHTTGASLDNK-RFTFVGTPCWMAPEVMQQVKGHNQKADIWSLGITAIELAAGQAPYAKYAPMKVLMLTLQNESPDIDTAASSCNQYSNYGQKYRKFSKACLNKDPAMRPSAKELLQSPFIKSKAKDRDSLIKVLLSEDTLPFERQRSDE-NLCPEKTP--TKAFSGEWNFDLQPL------GDHLNDIDNKESVDKTENETFE---NSEPI---------------------SYRITLRKRNPKKNNELEDISFDYVIGKDSVELLVRELVEADLLDGCDLLLVAHNMSELVANP 1438
SDS A S Q T W +E Y++ IG GAT+ V A C P R+ A+K INLEKC +S ++E+ +EI++M + N+VTYY SFV EL+++M + GS+LDIIK T +K + GV DESTIA+ILK+VL GL Y+H+NG +HRD+K GN+L+ +DG +QIADFGV+AFL+ T G +K R TFVGTPCWMAPEVM+QV+G++ KADIWS GITAIELA G APY +Y PMKVLMLTLQN+ P ++T YG+ +RK CL KDPA RP+A ELL+ F + KAK+R+ L++ LL++ P QR+ + P + K G+W + + G + + V + EN+ E NS P+ + + LR RN KK EL DI F++ G+D+ + + +EL A L++G D+++VA N+ ++V +P
Sbjct: 45 SDSPAALQSPQPAPTTGWPIVKEAYELQEVIGSGATAVVQAALCSPRQERV-AIKRINLEKCQTS--MDELLKEIQAMSQCSHPNVVTYYTSFVVKDELWLVMKLLSGGSVLDIIKHTFNKGEHRNGVLDESTIASILKEVLEGLDYLHKNGQIHRDVKAGNILLGEDGSVQIADFGVSAFLS-----TGGDVTRHKVRKTFVGTPCWMAPEVMEQVRGYDFKADIWSFGITAIELATGSAPYHRYPPMKVLMLTLQNDPPSLETGVEDKEMLKKYGKSFRKLISLCLQKDPAKRPTAAELLKCKFFQ-KAKNREYLMEKLLTKG--PNISQRAKKVRRVPGSSGHLHKTEDGDWEWSDDEMDERSEEGKAAVNHERSRRVKENENQHGEVNANSLPLEDLSIQHPQVQPLEKPSSAHGAVNMVLRLRNSKK--ELNDIRFEFTPGQDTADGVSQELFSAGLVNGHDVVVVAANLQKIVEDP 513
BLAST of Serine/threonine-protein kinase OSR1 vs. Ensembl Zebrafish
Match: oxsr1a (oxidative stress responsive kinase 1a [Source:ZFIN;Acc:ZDB-GENE-070620-25]) HSP 1 Score: 237.269 bits (604), Expect = 2.450e-74 Identity = 116/213 (54.46%), Postives = 153/213 (71.83%), Query Frame = 2
Query: 296 LEEIKREIKSMKNMKNENIVTYYASFVNGIELFIIMDVCQRGSLLDIIKRTQSKRDITYGVFDESTIATILKDVLRGLTYIHENGLVHRDLKCGNLLVKDDGIIQIADFGVAAFLAAQPMHTTGASLDNK-RFTFVGTPCWMAPEVMQQVKGHNQKADIWSLGITAIELAAGQAPYAKYAPMKVLMLTLQNESPDIDTAASSCNQYSNYGQKY 931
++E+ +EI++M + NIV+YY SFV EL+++M + GS+LD IK SK + GV DE +IATIL++VL GL Y+H+NG +HRD+K GN+L+ +DG +QIADFGV+AFLA T G NK R TFVGTPCWMAPEVM+QV+G++ KAD+WS GITAIELA G APY KY PMKVLMLTLQN+ P ++T + YG+ +
Sbjct: 1 MDELLKEIQAMSQCHHPNIVSYYTSFVVKDELWLVMKLLSGGSVLDFIKYIISKGEHKSGVMDEPSIATILREVLEGLEYLHKNGQIHRDVKAGNILLGEDGSVQIADFGVSAFLA-----TGGDMTRNKVRKTFVGTPCWMAPEVMEQVRGYDFKADLWSFGITAIELATGAAPYHKYPPMKVLMLTLQNDPPCLETGVTDKEMVKKYGKSF 208
BLAST of Serine/threonine-protein kinase OSR1 vs. Ensembl Zebrafish
Match: stk25b (serine/threonine kinase 25b [Source:ZFIN;Acc:ZDB-GENE-040426-2537]) HSP 1 Score: 198.749 bits (504), Expect = 4.912e-57 Identity = 115/301 (38.21%), Postives = 173/301 (57.48%), Query Frame = 2
Query: 161 EDYKINRSIGQGATSNVYEAECLPLNNR---LCAMKIINLEKCNSSSLLEEIKREIKSMKNMKNENIVTYYASFVNGIELFIIMDVCQRGSLLDIIKRTQSKRDITYGVFDESTIATILKDVLRGLTYIHENGLVHRDLKCGNLLVKDDGIIQIADFGVAAFLAAQPMHTTGASLDNKRFTFVGTPCWMAPEVMQQVKGHNQKADIWSLGITAIELAAGQAPYAKYAPMKVLMLTLQNESPDIDTAASSCNQYSNYGQKYRKFSKACLNKDPAMRPSAKELLQSPFIKSKAKDRDSLIKVL 1054
E + IG+G+ VY+ +NNR + A+KII+LE+ + +EI + + + YY S++ G +L+IIM+ GS LD++K G +E+ IATIL+++L+GL Y+H +HRD+K N+L+ + G +++ADFGVA L + KR TFVGTP WMAPEV++Q ++ KADIWSLGITAIELA G+ P + PM+VL L +N P ++ +Y + +++F +ACLNKDP RP+AKELL+ FI K L +++
Sbjct: 18 EYFTKQERIGKGSFGEVYKG----INNRTKEVVAIKIIDLEEAEDEIEDIQ--QEITVLSQCDSPYVTKYYGSYLKGTKLWIIMEYLGGGSALDLLKP---------GPLEETYIATILREILKGLEYLHSERKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQI---------KRNTFVGTPFWMAPEVIKQ-SAYDFKADIWSLGITAIELAKGEPPNSDLHPMRVLFLIPKNTPPTLE---------GSYSKPFKEFVEACLNKDPRFRPTAKELLKHKFITRYTKKTSYLTELI 284
BLAST of Serine/threonine-protein kinase OSR1 vs. Ensembl Xenopus
Match: hipk3 (homeodomain interacting protein kinase 3 [Source:Xenbase;Acc:XB-GENE-1010053]) HSP 1 Score: 345.51 bits (885), Expect = 1.356e-110 Identity = 203/501 (40.52%), Postives = 294/501 (58.68%), Query Frame = 2
Query: 134 QTIVWSNKREDYKINRSIGQGATSNVYEAECLPLNNRLCAMKIINLEKCNSSSLLEEIKREIKSMKNMKNENIVTYYASFVNGIELFIIMDVCQRGSLLDIIKRTQSKRDITYGVFDESTIATILKDVLRGLTYIHENGLVHRDLKCGNLLVKDDGIIQIADFGVAAFLAAQPMHTTGASLDNK-RFTFVGTPCWMAPEVMQQVKGHNQKADIWSLGITAIELAAGQAPYAKYAPMKVLMLTLQNESPDIDTAASSCNQYSNYGQKYRKFSKACLNKDPAMRPSAKELLQSPFIKSKAKDRDSLI-KVLLSEDTLPFERQRSDENLCPEKTPTKAFSGEWNFDLQPLGDHLNDIDNKESVDKT--ENET-------------------------------FENSEPISYRITLRKRNPKKNNELEDISFDYVIGKDSVELLVRELVEADLLDGCDLLLVAHNMSELVANP-SVRERVFALNSP-PSTGVANEQELYGYAKV 1525
Q I W R+ Y++ IG GAT+ V A C P R+ A+K INLEKC +S ++E+ +EI++M + NIVTYY SFV EL+++M + GS+LDIIK + + GV +ES IATILK+VL GL Y+H NG +HRDLK GN+L+ +DG +QIADFGV++FLA T G NK R TFVGTPCWMAPEVM+QV+G++ KAD+WS GITAIELA G APY KY PMKVLMLTLQN+ P ++T YG+ +RK CL KDP+ RP+A ELL+ F + K+K+R+ LI K+L+ + ++ K G+W + L + ++ + S +K+ +NE+ E+ P + + LR RN +K EL DI F++ G+D+ + + +EL A L+DG D+++VA N+ +++ +P + + F L S T + +E +L G+A++
Sbjct: 124 QPIGWPICRDSYELQEVIGSGATAVVQAALCKPRQERV-AIKRINLEKCQTS--MDELLKEIQAMSQCSHPNIVTYYTSFVVKEELWLVMKLLSGGSMLDIIKHVVGRGEHKNGVLEESIIATILKEVLEGLDYLHRNGQIHRDLKAGNILLGEDGSVQIADFGVSSFLA-----TGGDVTRNKVRKTFVGTPCWMAPEVMEQVRGYDFKADMWSFGITAIELATGAAPYHKYPPMKVLMLTLQNDPPTLETGVEDKEMMRKYGKSFRKLISLCLQKDPSKRPTAAELLKCKFFQ-KSKNREYLIEKLLIKTPNIALRGKKVRRVPGSSGHLHKNEDGDWEWSDDELEEKSSEFKDSYSKEKSRRDNESNNAEITTDSNMQTRIQNLSLQDTQAQSNESHVESGLPSAVNLVLRLRNSRK--ELNDIRFEFTPGRDTADGVSQELFSAGLVDGHDVVIVAANLQKMIDDPLTYKSLTFKLVSGCDGTEIPDEVKLIGFAQL 613
BLAST of Serine/threonine-protein kinase OSR1 vs. Ensembl Xenopus
Match: sap130 (Sin3A associated protein 130kDa [Source:Xenbase;Acc:XB-GENE-6083596]) HSP 1 Score: 339.347 bits (869), Expect = 2.666e-110 Identity = 198/469 (42.22%), Postives = 283/469 (60.34%), Query Frame = 2
Query: 137 TIVWSNKREDYKINRSIGQGATSNVYEAECLPLNNRLCAMKIINLEKCNSSSLLEEIKREIKSMKNMKNENIVTYYASFVNGIELFIIMDVCQRGSLLDIIKRTQSKRDITYGVFDESTIATILKDVLRGLTYIHENGLVHRDLKCGNLLVKDDGIIQIADFGVAAFLAAQPMHTTGASLDNK-RFTFVGTPCWMAPEVMQQVKGHNQKADIWSLGITAIELAAGQAPYAKYAPMKVLMLTLQNESPDIDTAASSCNQYSNYGQKYRKFSKACLNKDPAMRPSAKELLQSPFIKSKAKDRDSLIKVLLSEDTLPFERQRSDENLCPEKTPT--KAFSGEWNFDLQPLGDHLNDIDNKESVDKTENETFENSEPISYRITLRKRNPKKNNELEDISFDYVIGKDSVELLVRELVEADLLDGCDLLLVAHNMSELVANPSVRERV-FALNSP--PSTGVANEQELYGYAKV 1525
++ WS R+DY++ IG GAT+ V A C P ++ A+K INLEKC +S ++E+ +EI++M + NIV+YY SFV EL+++M + GS+LDIIK +K + GV DE++IAT+LK+VL GL Y+H+NG +HRD+K GN+L+ +DG +QIADFGV+AFLA T G NK R TFVGTPCWMAPEVM+QV+G++ KADIWS GITAIELA G APY KY PMKVLMLTLQN+ P ++T YG+ +RK +CL KDP RP+A ELL+ F + + + L + P + +R P + K G W + +++D + K P + + + RN KK EL DI F++ G+D+ + + +ELV A L+DG DL++VA N+ ++V P V F L S PS + ++ +L G+A++
Sbjct: 8 SLPWSINRDDYELQEVIGSGATAVVQAAFCAPKKEKV-AIKRINLEKCQTS--MDELLKEIQAMSQCHHPNIVSYYTSFVVKDELWLVMKLLSGGSVLDIIKHIIAKGEHKNGVLDEASIATMLKEVLEGLEYLHKNGQIHRDVKAGNILLGEDGSVQIADFGVSAFLA-----TGGDITRNKVRKTFVGTPCWMAPEVMEQVRGYDFKADIWSFGITAIELATGAAPYHKYPPMKVLMLTLQNDPPTLETGVQDKEMLKKYGKSFRKMISSCLQKDPEKRPTAAELLKHKFFQKAKELGAEWVPSLFIFTSAPIQVRR-----VPGSSGRLHKTEDGGWEWS-------DDELDEESEEGKAAILQLRVRPPAKFPLYIN-RNTKK--ELNDIRFEFTPGRDTADGVSQELVSAGLVDGRDLVIVAANLQKIVDEPQTHRSVTFKLASGVDPSD-IPDDGKLVGFAQL 452
BLAST of Serine/threonine-protein kinase OSR1 vs. Ensembl Xenopus
Match: hipk3 (homeodomain interacting protein kinase 3 [Source:Xenbase;Acc:XB-GENE-1010053]) HSP 1 Score: 342.813 bits (878), Expect = 6.579e-110 Identity = 194/441 (43.99%), Postives = 275/441 (62.36%), Query Frame = 2
Query: 134 QTIVWSNKREDYKINRSIGQGATSNVYEAECLPLNNRLCAMKIINLEKCNSSSLLEEIKREIKSMKNMKNENIVTYYASFVNGIELFIIMDVCQRGSLLDIIKRTQSKRDITYGVFDESTIATILKDVLRGLTYIHENGLVHRDLKCGNLLVKDDGIIQIADFGVAAFLAAQPMHTTGASLDNK-RFTFVGTPCWMAPEVMQQVKGHNQKADIWSLGITAIELAAGQAPYAKYAPMKVLMLTLQNESPDIDTAASSCNQYSNYGQKYRKFSKACLNKDPAMRPSAKELLQSPFIKSKAKDRDSLI-KVLLSEDTLPFERQRSDENLCPEKTPTKAFSGEWNF---DLQPLGDHLNDIDNKESVD-KTENETFENSEPISYRITLRKRNPKKNNELEDISFDYVIGKDSVELLVRELVEADLLDGCDLLLVAHNMSELVANP 1438
Q I W R+ Y++ IG GAT+ V A C P R+ A+K INLEKC +S ++E+ +EI++M + NIVTYY SFV EL+++M + GS+LDIIK + + GV +ES IATILK+VL GL Y+H NG +HRDLK GN+L+ +DG +QIADFGV++FLA T G NK R TFVGTPCWMAPEVM+QV+G++ KAD+WS GITAIELA G APY KY PMKVLMLTLQN+ P ++T YG+ +RK CL KDP+ RP+A ELL+ F + K+K+R+ LI K+L+ + ++ K G+W + +L+ D +KE V ++ +N+E S +T +N +K EL DI F++ G+D+ + + +EL A L+DG D+++VA N+ +++ +P
Sbjct: 124 QPIGWPICRDSYELQEVIGSGATAVVQAALCKPRQERV-AIKRINLEKCQTS--MDELLKEIQAMSQCSHPNIVTYYTSFVVKEELWLVMKLLSGGSMLDIIKHVVGRGEHKNGVLEESIIATILKEVLEGLDYLHRNGQIHRDLKAGNILLGEDGSVQIADFGVSSFLA-----TGGDVTRNKVRKTFVGTPCWMAPEVMEQVRGYDFKADMWSFGITAIELATGAAPYHKYPPMKVLMLTLQNDPPTLETGVEDKEMMRKYGKSFRKLISLCLQKDPSKRPTAAELLKCKFFQ-KSKNREYLIEKLLIKTPNIALRGKKVRRVPGSSGHLHKNEDGDWEWSDDELEEKSSEFKDSYSKEKVIFNPTPKSVDNNELKS--LTFFIKNSRK--ELNDIRFEFTPGRDTADGVSQELFSAGLVDGHDVVIVAANLQKMIDDP 551
BLAST of Serine/threonine-protein kinase OSR1 vs. Ensembl Xenopus
Match: hipk3 (homeodomain interacting protein kinase 3 [Source:Xenbase;Acc:XB-GENE-1010053]) HSP 1 Score: 343.969 bits (881), Expect = 1.017e-109 Identity = 207/524 (39.50%), Postives = 296/524 (56.49%), Query Frame = 2
Query: 134 QTIVWSNKREDYKINRSIGQGATSNVYEAECLPLNNRLCAMKIINLEKCNSSSLLEEIKREIKSMKNMKNENIVTYYASFVNGIELFIIMDVCQRGSLLDIIKRTQSKRDITYGVFDESTIATILKDVLRGLTYIHENGLVHRDLKCGNLLVKDDGIIQIADFGVAAFLAAQPMHTTGASLDNK-RFTFVGTPCWMAPEVMQQVKGHNQKADIWSLGITAIELAAGQAPYAKYAPMKVLMLTLQNESPDIDTAASSCNQYSNYGQKYRKFSKACLNKDPAMRPSAKELLQSPFIKSKAKDRDSLIKVLL------------------SEDTLPFERQRSDENLCPEKTPT------KAFSGEWNFDLQPLGDHLNDIDNKESVDKT--ENET-------------------------------FENSEPISYRITLRKRNPKKNNELEDISFDYVIGKDSVELLVRELVEADLLDGCDLLLVAHNMSELVANP-SVRERVFALNSP-PSTGVANEQELYGYAKV 1525
Q I W R+ Y++ IG GAT+ V A C P R+ A+K INLEKC +S ++E+ +EI++M + NIVTYY SFV EL+++M + GS+LDIIK + + GV +ES IATILK+VL GL Y+H NG +HRDLK GN+L+ +DG +QIADFGV++FLA T G NK R TFVGTPCWMAPEVM+QV+G++ KAD+WS GITAIELA G APY KY PMKVLMLTLQN+ P ++T YG+ +RK CL KDP+ RP+A ELL+ F + K+K+R+ LI+ LL +P D N + P K G+W + L + ++ + S +K+ +NE+ E+ P + + LR RN +K EL DI F++ G+D+ + + +EL A L+DG D+++VA N+ +++ +P + + F L S T + +E +L G+A++
Sbjct: 124 QPIGWPICRDSYELQEVIGSGATAVVQAALCKPRQERV-AIKRINLEKCQTS--MDELLKEIQAMSQCSHPNIVTYYTSFVVKEELWLVMKLLSGGSMLDIIKHVVGRGEHKNGVLEESIIATILKEVLEGLDYLHRNGQIHRDLKAGNILLGEDGSVQIADFGVSSFLA-----TGGDVTRNKVRKTFVGTPCWMAPEVMEQVRGYDFKADMWSFGITAIELATGAAPYHKYPPMKVLMLTLQNDPPTLETGVEDKEMMRKYGKSFRKLISLCLQKDPSKRPTAAELLKCKFFQ-KSKNREYLIEKLLIKTPNIALRGKKAEQSPGKTSLMPGSETEQDNNRRVRRVPGSSGHLHKNEDGDWEWSDDELEEKSSEFKDSYSKEKSRRDNESNNAEITTDSNMQTRIQNLSLQDTQAQSNESHVESGLPSAVNLVLRLRNSRK--ELNDIRFEFTPGRDTADGVSQELFSAGLVDGHDVVIVAANLQKMIDDPLTYKSLTFKLVSGCDGTEIPDEVKLIGFAQL 636
BLAST of Serine/threonine-protein kinase OSR1 vs. Ensembl Xenopus
Match: hipk3 (homeodomain interacting protein kinase 3 [Source:Xenbase;Acc:XB-GENE-1010053]) HSP 1 Score: 332.028 bits (850), Expect = 1.042e-106 Identity = 193/470 (41.06%), Postives = 279/470 (59.36%), Query Frame = 2
Query: 134 QTIVWSNKREDYKINRSIGQGATSNVYEAECLPLNNRLCAMKIINLEKCNSSSLLEEIKREIKSMKNMKNENIVTYYASFVNGIELFIIMDVCQRGSLLDIIKRTQSKRDITYGVFDESTIATILKDVLRGLTYIHENGLVHRDLKCGNLLVKDDGIIQIADFGVAAFLAAQPMHTTGASLDNK-RFTFVGTPCWMAPEVMQQVKGHNQKADIWSLGITAIELAAGQAPYAKYAPMKVLMLTLQNESPDIDTAASSCNQYSNYGQKYRKFSKACLNKDPAMRPSAKELLQSPFIKSKAKDRDSLI-KVLLSEDTLPFERQRSDENLCPEKTPTKAFSGEWNFDLQPLGDHLNDIDNKESVDKT----------------ENETFENSE-------PIS------YRITLRK----RNPKKNNELEDISFDYVIGKDSVELLVRELVEADLLDGCDLLLVAHNMSELVANP 1438
Q I W R+ Y++ IG GAT+ V A C P R+ A+K INLEKC +S ++E+ +EI++M + NIVTYY SFV EL+++M + GS+LDIIK + + GV +ES IATILK+VL GL Y+H NG +HRDLK GN+L+ +DG +QIADFGV++FLA T G NK R TFVGTPCWMAPEVM+QV+G++ KAD+WS GITAIELA G APY KY PMKVLMLTLQN+ P ++T YG+ +RK CL KDP+ RP+A ELL+ F + K+K+R+ LI K+L+ + ++ K G+W + L + ++ + S +K+ +N + ++++ PI Y + + RN +K EL DI F++ G+D+ + + +EL A L+DG D+++VA N+ +++ +P
Sbjct: 16 QPIGWPICRDSYELQEVIGSGATAVVQAALCKPRQERV-AIKRINLEKCQTS--MDELLKEIQAMSQCSHPNIVTYYTSFVVKEELWLVMKLLSGGSMLDIIKHVVGRGEHKNGVLEESIIATILKEVLEGLDYLHRNGQIHRDLKAGNILLGEDGSVQIADFGVSSFLA-----TGGDVTRNKVRKTFVGTPCWMAPEVMEQVRGYDFKADMWSFGITAIELATGAAPYHKYPPMKVLMLTLQNDPPTLETGVEDKEMMRKYGKSFRKLISLCLQKDPSKRPTAAELLKCKFFQ-KSKNREYLIEKLLIKTPNIALRGKKVRRVPGSSGHLHKNEDGDWEWSDDELEEKSSEFKDSYSKEKSAFSPQITTDSNMQTRIQNLSLQDTQVRNGIALPIYLSFEFLYNLNVWSVFFFRNSRK--ELNDIRFEFTPGRDTADGVSQELFSAGLVDGHDVVIVAANLQKMIDDP 474
BLAST of Serine/threonine-protein kinase OSR1 vs. Ensembl Mouse
Match: Stk39 (serine/threonine kinase 39 [Source:MGI Symbol;Acc:MGI:1858416]) HSP 1 Score: 345.125 bits (884), Expect = 2.865e-111 Identity = 205/499 (41.08%), Postives = 294/499 (58.92%), Query Frame = 2
Query: 146 WSNKREDYKINRSIGQGATSNVYEAECLPLNNRLCAMKIINLEKCNSSSLLEEIKREIKSMKNMKNENIVTYYASFVNGIELFIIMDVCQRGSLLDIIKRTQSKRDITYGVFDESTIATILKDVLRGLTYIHENGLVHRDLKCGNLLVKDDGIIQIADFGVAAFLAAQPMHTTGASLDNK-RFTFVGTPCWMAPEVMQQVKGHNQKADIWSLGITAIELAAGQAPYAKYAPMKVLMLTLQNESPDIDTAASSCNQYSNYGQKYRKFSKACLNKDPAMRPSAKELLQSPFIKSKAKDRDSLIKVLLSEDTLPFERQRSDE-NLCPEKTP--TKAFSGEWNFDLQPLGDHLNDIDNKESVDKTENETFENSE---------------------------------PISYRITLRKRNPKKNNELEDISFDYVIGKDSVELLVRELVEADLLDGCDLLLVAHNMSELVANP-SVRERVFALNSP-PSTGVANEQELYGYAKV 1525
W R+ Y++ IG GAT+ V A C P R+ A+K INLEKC +S ++E+ +EI++M + N+VTYY SFV EL+++M + GS+LDIIK ++ + GV +E+ IATILK+VL GL Y+H NG +HRDLK GN+L+ +DG +QIADFGV+AFLA T G NK R TFVGTPCWMAPEVM+QV+G++ KAD+WS GITAIELA G APY KY PMKVLMLTLQN+ P ++T YG+ +RK CL KDP+ RP+A ELL+ F + KAK+R+ LI+ LL+ P QR+ + P + K G+W + + + + S +K+ ENSE P + + LR RN +K EL DI F++ G+D+ + + +EL A L+DG D+++VA N+ ++V +P +++ F L S + + +E +L G+A++
Sbjct: 68 WPICRDAYELQEVIGSGATAVVQAALCKPRQERV-AIKRINLEKCQTS--MDELLKEIQAMSQCSHPNVVTYYTSFVVKDELWLVMKLLSGGSMLDIIKYIVNRGEHKNGVLEEAIIATILKEVLEGLDYLHRNGQIHRDLKAGNILLGEDGSVQIADFGVSAFLA-----TGGDVTRNKVRKTFVGTPCWMAPEVMEQVRGYDFKADMWSFGITAIELATGAAPYHKYPPMKVLMLTLQNDPPTLETGVEDKEMMKKYGKSFRKLLSLCLQKDPSKRPTAAELLKCKFFQ-KAKNREYLIEKLLTR--TPDIAQRAKKVRRVPGSSGHLHKTEDGDWEWSDDEMDEKSEEGKAAASQEKSRRVKEENSEISVNAGGIPEQIQSLSVHDSQAQPNANEDYREGPCAVNLVLRLRNSRK--ELNDIRFEFTPGRDTADGVSQELFSAGLVDGHDVVIVAANLQKIVDDPKALKTLTFKLASGCDGSEIPDEVKLIGFAQL 553
BLAST of Serine/threonine-protein kinase OSR1 vs. Ensembl Mouse
Match: Oxsr1 (oxidative-stress responsive 1 [Source:MGI Symbol;Acc:MGI:1917378]) HSP 1 Score: 317.39 bits (812), Expect = 5.388e-101 Identity = 163/316 (51.58%), Postives = 214/316 (67.72%), Query Frame = 2
Query: 146 WSNKREDYKINRSIGQGATSNVYEAECLPLNNRLCAMKIINLEKCNSSSLLEEIKREIKSMKNMKNENIVTYYASFVNGIELFIIMDVCQRGSLLDIIKRTQSKRDITYGVFDESTIATILKDVLRGLTYIHENGLVHRDLKCGNLLVKDDGIIQIADFGVAAFLAAQPMHTTGASLDNK-RFTFVGTPCWMAPEVMQQVKGHNQKADIWSLGITAIELAAGQAPYAKYAPMKVLMLTLQNESPDIDTAASSCNQYSNYGQKYRKFSKACLNKDPAMRPSAKELLQSPFIKSKAKDRDSLIKVLLSEDTLPFERQR 1090
WS R+DY++ IG GAT+ V A C P R+ A+K INLEKC +S ++E+ +EI++M + NIV+YY SFV EL+++M + GS+LDIIK +K + GV DE TIATIL++VL GL Y+H+NG +HRD+K GN+L+ +DG +QIADFGV+AFLA T G NK R TFVGTPCWMAPEVM+QV+G++ KADIWS GITAIELA G APY KY PMKVLMLTLQN+ P ++T YG+ +RK CL KDP RP+A ELL+ F + KAK+++ L + +L ER +
Sbjct: 10 WSINRDDYELQEVIGSGATAVVQAAYCAPKKERV-AIKRINLEKCQTS--MDELLKEIQAMSQCHHPNIVSYYTSFVVKDELWLVMKLLSGGSVLDIIKHIVAKGEHKSGVLDEPTIATILREVLEGLEYLHKNGQIHRDVKAGNILLGEDGSVQIADFGVSAFLA-----TGGDITRNKVRKTFVGTPCWMAPEVMEQVRGYDFKADIWSFGITAIELATGAAPYHKYPPMKVLMLTLQNDPPSLETGVQDKEMLKKYGKSFRKMISLCLQKDPEKRPTAAELLRHKFFQ-KAKNKEFLQEKILQRAPTISERSK 316 HSP 2 Score: 59.6918 bits (143), Expect = 6.947e-9 Identity = 39/100 (39.00%), Postives = 61/100 (61.00%), Query Frame = 2
Query: 1232 ENSEPISYRITLRKRNPKKNNELEDISFDYVIGKDSVELLVRELVEADLLDGCDLLLVAHNMSELVANP-SVRERVFALNSP-PSTGVANEQELYGYAKV 1525
E PIS + LR RN KK EL DI F++ G+D+ E + +EL+ A L+DG DL++VA N+ ++V P S R F L S + + ++ +L G+A++
Sbjct: 429 ETKIPIS--LVLRLRNSKK--ELNDIRFEFTPGRDTAEGVSQELISAGLVDGRDLVIVAANLQKIVEEPQSNRSVTFKLASGVEGSDIPDDGKLIGFAQL 524
BLAST of Serine/threonine-protein kinase OSR1 vs. Ensembl Mouse
Match: Stk26 (serine/threonine kinase 26 [Source:MGI Symbol;Acc:MGI:1917665]) HSP 1 Score: 197.978 bits (502), Expect = 5.217e-57 Identity = 113/293 (38.57%), Postives = 171/293 (58.36%), Query Frame = 2
Query: 185 IGQGATSNVYEAECLPLNNR---LCAMKIINLEKCNSSSLLEEIKREIKSMKNMKNENIVTYYASFVNGIELFIIMDVCQRGSLLDIIKRTQSKRDITYGVFDESTIATILKDVLRGLTYIHENGLVHRDLKCGNLLVKDDGIIQIADFGVAAFLAAQPMHTTGASLDNKRFTFVGTPCWMAPEVMQQVKGHNQKADIWSLGITAIELAAGQAPYAKYAPMKVLMLTLQNESPDIDTAASSCNQYSNYGQKYRKFSKACLNKDPAMRPSAKELLQSPFIKSKAKDRDSLIKVL 1054
IG+G+ V++ ++NR + A+KII+LE+ + +EI + + + YY S++ G +L+IIM+ GS LD+++ G FDE IAT+LK++L+GL Y+H +HRD+K N+L+ + G +++ADFGVA L + KR TFVGTP WMAPEV+QQ ++ KADIWSLGITAIELA G+ P + PM+VL L +N P + ++ + +++F ACLNKDP+ RP+AKELL+ FI +K L +++
Sbjct: 30 IGKGSFGEVFKG----IDNRTQQVVAIKIIDLEEAEDEIEDIQ--QEITVLSQCDSSYVTKYYGSYLKGSKLWIIMEYLGGGSALDLLRA---------GPFDEFQIATMLKEILKGLDYLHSEKKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQI---------KRNTFVGTPFWMAPEVIQQ-SAYDSKADIWSLGITAIELAKGEPPNSDMHPMRVLFLIPKNNPPTL---------IGDFTKSFKEFIDACLNKDPSFRPTAKELLKHKFIVKNSKKTSYLTELI 288
BLAST of Serine/threonine-protein kinase OSR1 vs. Ensembl Mouse
Match: Stk26 (serine/threonine kinase 26 [Source:MGI Symbol;Acc:MGI:1917665]) HSP 1 Score: 197.978 bits (502), Expect = 9.378e-57 Identity = 113/293 (38.57%), Postives = 171/293 (58.36%), Query Frame = 2
Query: 185 IGQGATSNVYEAECLPLNNR---LCAMKIINLEKCNSSSLLEEIKREIKSMKNMKNENIVTYYASFVNGIELFIIMDVCQRGSLLDIIKRTQSKRDITYGVFDESTIATILKDVLRGLTYIHENGLVHRDLKCGNLLVKDDGIIQIADFGVAAFLAAQPMHTTGASLDNKRFTFVGTPCWMAPEVMQQVKGHNQKADIWSLGITAIELAAGQAPYAKYAPMKVLMLTLQNESPDIDTAASSCNQYSNYGQKYRKFSKACLNKDPAMRPSAKELLQSPFIKSKAKDRDSLIKVL 1054
IG+G+ V++ ++NR + A+KII+LE+ + +EI + + + YY S++ G +L+IIM+ GS LD+++ G FDE IAT+LK++L+GL Y+H +HRD+K N+L+ + G +++ADFGVA L + KR TFVGTP WMAPEV+QQ ++ KADIWSLGITAIELA G+ P + PM+VL L +N P + ++ + +++F ACLNKDP+ RP+AKELL+ FI +K L +++
Sbjct: 30 IGKGSFGEVFKG----IDNRTQQVVAIKIIDLEEAEDEIEDIQ--QEITVLSQCDSSYVTKYYGSYLKGSKLWIIMEYLGGGSALDLLRA---------GPFDEFQIATMLKEILKGLDYLHSEKKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQI---------KRNTFVGTPFWMAPEVIQQ-SAYDSKADIWSLGITAIELAKGEPPNSDMHPMRVLFLIPKNNPPTL---------IGDFTKSFKEFIDACLNKDPSFRPTAKELLKHKFIVKNSKKTSYLTELI 288
BLAST of Serine/threonine-protein kinase OSR1 vs. Ensembl Mouse
Match: Stk24 (serine/threonine kinase 24 [Source:MGI Symbol;Acc:MGI:2385007]) HSP 1 Score: 196.438 bits (498), Expect = 3.933e-56 Identity = 113/293 (38.57%), Postives = 172/293 (58.70%), Query Frame = 2
Query: 185 IGQGATSNVYEAECLPLNNR---LCAMKIINLEKCNSSSLLEEIKREIKSMKNMKNENIVTYYASFVNGIELFIIMDVCQRGSLLDIIKRTQSKRDITYGVFDESTIATILKDVLRGLTYIHENGLVHRDLKCGNLLVKDDGIIQIADFGVAAFLAAQPMHTTGASLDNKRFTFVGTPCWMAPEVMQQVKGHNQKADIWSLGITAIELAAGQAPYAKYAPMKVLMLTLQNESPDIDTAASSCNQYSNYGQKYRKFSKACLNKDPAMRPSAKELLQSPFIKSKAKDRDSLIKVL 1054
IG+G+ V++ ++NR + A+KII+LE+ + +EI + + + YY S++ +L+IIM+ GS LD+++ G DE IATIL+++L+GL Y+H +HRD+K N+L+ + G +++ADFGVA L + KR TFVGTP WMAPEV++Q ++ KADIWSLGITAIELA G+ P+++ PMKVL L +N P ++ NY + ++F +ACLNK+P+ RP+AKELL+ FI AK L +++
Sbjct: 30 IGKGSFGEVFKG----IDNRTQKVVAIKIIDLEEAEDEIEDIQ--QEITVLSQCDSPYVTKYYGSYLKDTKLWIIMEYLGGGSALDLLEP---------GPLDEIQIATILREILKGLDYLHSEKKIHRDIKAANVLLSEHGEVKLADFGVAGQLTDTQI---------KRNTFVGTPFWMAPEVIKQ-SAYDSKADIWSLGITAIELAKGEPPHSELHPMKVLFLIPKNNPPTLE---------GNYSKPLKEFVEACLNKEPSFRPTAKELLKHKFIIRNAKKTSYLTELI 288
BLAST of Serine/threonine-protein kinase OSR1 vs. UniProt/SwissProt
Match: sp|Q9Z1W9|STK39_MOUSE (STE20/SPS1-related proline-alanine-rich protein kinase OS=Mus musculus OX=10090 GN=Stk39 PE=1 SV=1) HSP 1 Score: 345.125 bits (884), Expect = 2.004e-110 Identity = 205/499 (41.08%), Postives = 294/499 (58.92%), Query Frame = 2
Query: 146 WSNKREDYKINRSIGQGATSNVYEAECLPLNNRLCAMKIINLEKCNSSSLLEEIKREIKSMKNMKNENIVTYYASFVNGIELFIIMDVCQRGSLLDIIKRTQSKRDITYGVFDESTIATILKDVLRGLTYIHENGLVHRDLKCGNLLVKDDGIIQIADFGVAAFLAAQPMHTTGASLDNK-RFTFVGTPCWMAPEVMQQVKGHNQKADIWSLGITAIELAAGQAPYAKYAPMKVLMLTLQNESPDIDTAASSCNQYSNYGQKYRKFSKACLNKDPAMRPSAKELLQSPFIKSKAKDRDSLIKVLLSEDTLPFERQRSDE-NLCPEKTP--TKAFSGEWNFDLQPLGDHLNDIDNKESVDKTENETFENSE---------------------------------PISYRITLRKRNPKKNNELEDISFDYVIGKDSVELLVRELVEADLLDGCDLLLVAHNMSELVANP-SVRERVFALNSP-PSTGVANEQELYGYAKV 1525
W R+ Y++ IG GAT+ V A C P R+ A+K INLEKC +S ++E+ +EI++M + N+VTYY SFV EL+++M + GS+LDIIK ++ + GV +E+ IATILK+VL GL Y+H NG +HRDLK GN+L+ +DG +QIADFGV+AFLA T G NK R TFVGTPCWMAPEVM+QV+G++ KAD+WS GITAIELA G APY KY PMKVLMLTLQN+ P ++T YG+ +RK CL KDP+ RP+A ELL+ F + KAK+R+ LI+ LL+ P QR+ + P + K G+W + + + + S +K+ ENSE P + + LR RN +K EL DI F++ G+D+ + + +EL A L+DG D+++VA N+ ++V +P +++ F L S + + +E +L G+A++
Sbjct: 68 WPICRDAYELQEVIGSGATAVVQAALCKPRQERV-AIKRINLEKCQTS--MDELLKEIQAMSQCSHPNVVTYYTSFVVKDELWLVMKLLSGGSMLDIIKYIVNRGEHKNGVLEEAIIATILKEVLEGLDYLHRNGQIHRDLKAGNILLGEDGSVQIADFGVSAFLA-----TGGDVTRNKVRKTFVGTPCWMAPEVMEQVRGYDFKADMWSFGITAIELATGAAPYHKYPPMKVLMLTLQNDPPTLETGVEDKEMMKKYGKSFRKLLSLCLQKDPSKRPTAAELLKCKFFQ-KAKNREYLIEKLLTR--TPDIAQRAKKVRRVPGSSGHLHKTEDGDWEWSDDEMDEKSEEGKAAASQEKSRRVKEENSEISVNAGGIPEQIQSLSVHDSQAQPNANEDYREGPCAVNLVLRLRNSRK--ELNDIRFEFTPGRDTADGVSQELFSAGLVDGHDVVIVAANLQKIVDDPKALKTLTFKLASGCDGSEIPDEVKLIGFAQL 553
BLAST of Serine/threonine-protein kinase OSR1 vs. UniProt/SwissProt
Match: sp|O88506|STK39_RAT (STE20/SPS1-related proline-alanine-rich protein kinase OS=Rattus norvegicus OX=10116 GN=Stk39 PE=1 SV=2) HSP 1 Score: 342.428 bits (877), Expect = 2.004e-109 Identity = 204/501 (40.72%), Postives = 293/501 (58.48%), Query Frame = 2
Query: 140 IVWSNKREDYKINRSIGQGATSNVYEAECLPLNNRLCAMKIINLEKCNSSSLLEEIKREIKSMKNMKNENIVTYYASFVNGIELFIIMDVCQRGSLLDIIKRTQSKRDITYGVFDESTIATILKDVLRGLTYIHENGLVHRDLKCGNLLVKDDGIIQIADFGVAAFLAAQPMHTTGASLDNK-RFTFVGTPCWMAPEVMQQVKGHNQKADIWSLGITAIELAAGQAPYAKYAPMKVLMLTLQNESPDIDTAASSCNQYSNYGQKYRKFSKACLNKDPAMRPSAKELLQSPFIKSKAKDRDSLIKVLLSEDTLPFERQRSDE-NLCPEKTP--TKAFSGEWNFDLQPLGDHLNDIDNKESVDKTENETFENSE---------------------------------PISYRITLRKRNPKKNNELEDISFDYVIGKDSVELLVRELVEADLLDGCDLLLVAHNMSELVANP-SVRERVFALNSP-PSTGVANEQELYGYAKV 1525
+ W R+ Y++ IG GAT+ V A C P R+ A+K INLEKC +S ++E+ +EI++M + N+VTYY SFV EL+++M + GS+LDIIK ++ + GV +E+ IATILK+VL GL Y+H NG +HRDLK GN+L+ +DG +QIADFGV+AFLA T G NK R TFVGTPCWMAPEVM+QV+G++ KAD+WS GITAIELA G APY KY PMKVLMLTLQN+ P ++T YG+ +RK CL KDP+ RP+A ELL+ F + KAK+R+ LI+ LL+ P QR+ + P + K G+W + + + + S +K+ EN E P + + LR RN +K EL DI F++ G+D+ + + +EL A L+DG D+++VA N+ ++V +P +++ F L S + +E +L G+A++
Sbjct: 63 VGWPICRDAYELQEVIGSGATAVVQAALCKPRQERV-AIKRINLEKCQTS--MDELLKEIQAMSQCSHPNVVTYYTSFVVKDELWLVMKLLSGGSMLDIIKYIVNRGEHKNGVLEEAIIATILKEVLEGLDYLHRNGQIHRDLKAGNILLGEDGSVQIADFGVSAFLA-----TGGDVTRNKVRKTFVGTPCWMAPEVMEQVRGYDFKADMWSFGITAIELATGAAPYHKYPPMKVLMLTLQNDPPTLETGVEDKEMMKKYGKSFRKLLSLCLQKDPSKRPTAAELLKCKFFQ-KAKNREYLIEKLLTR--TPDIAQRAKKVRRVPGSSGHLHKTEDGDWEWSDDEMDEKSEEGKAAASQEKSRRVKEENPEISVNAGGIPEQIQSLSVHDSQGQPNANEDYREGPCAVNLVLRLRNSRK--ELNDIRFEFTPGRDTADGVSQELFSAGLVDGHDVVIVAANLQKIVDDPKALKTLTFKLASGCDGAEIPDEVKLIGFAQL 550
BLAST of Serine/threonine-protein kinase OSR1 vs. UniProt/SwissProt
Match: sp|Q9UEW8|STK39_HUMAN (STE20/SPS1-related proline-alanine-rich protein kinase OS=Homo sapiens OX=9606 GN=STK39 PE=1 SV=3) HSP 1 Score: 339.732 bits (870), Expect = 1.460e-108 Identity = 202/500 (40.40%), Postives = 293/500 (58.60%), Query Frame = 2
Query: 146 WSNKREDYKINRSIGQGATSNVYEAECLPLNNRLCAMKIINLEKCNSSSLLEEIKREIKSMKNMKNENIVTYYASFVNGIELFIIMDVCQRGSLLDIIKRTQSKRDITYGVFDESTIATILKDVLRGLTYIHENGLVHRDLKCGNLLVKDDGIIQIADFGVAAFLAAQPMHTTGASLDNK-RFTFVGTPCWMAPEVMQQVKGHNQKADIWSLGITAIELAAGQAPYAKYAPMKVLMLTLQNESPDIDTAASSCNQYSNYGQKYRKFSKACLNKDPAMRPSAKELLQSPFIKSKAKDRDSLIKVLLSEDTLPFERQRSDE-NLCPEKTP--TKAFSGEWNFDLQPLGDHLNDIDNKESVDKTE----------------------------------NETFENSEPISYRITLRKRNPKKNNELEDISFDYVIGKDSVELLVRELVEADLLDGCDLLLVAHNMSELVANP-SVRERVFALNSP-PSTGVANEQELYGYAKV 1525
W R+ Y++ IG GAT+ V A C P R+ A+K INLEKC +S ++E+ +EI++M + N+VTYY SFV EL+++M + GS+LDIIK ++ + GV +E+ IATILK+VL GL Y+H NG +HRDLK GN+L+ +DG +QIADFGV+AFLA T G NK R TFVGTPCWMAPEVM+QV+G++ KAD+WS GITAIELA G APY KY PMKVLMLTLQN+ P ++T YG+ +RK CL KDP+ RP+A ELL+ F + KAK+R+ LI+ LL+ P QR+ + P + K G+W + + + + S +K+ NE + + + + LR RN +K EL DI F++ G+D+ + + +EL A L+DG D+++VA N+ ++V +P +++ F L S + + +E +L G+A++
Sbjct: 56 WPICRDAYELQEVIGSGATAVVQAALCKPRQERV-AIKRINLEKCQTS--MDELLKEIQAMSQCSHPNVVTYYTSFVVKDELWLVMKLLSGGSMLDIIKYIVNRGEHKNGVLEEAIIATILKEVLEGLDYLHRNGQIHRDLKAGNILLGEDGSVQIADFGVSAFLA-----TGGDVTRNKVRKTFVGTPCWMAPEVMEQVRGYDFKADMWSFGITAIELATGAAPYHKYPPMKVLMLTLQNDPPTLETGVEDKEMMKKYGKSFRKLLSLCLQKDPSKRPTAAELLKCKFFQ-KAKNREYLIEKLLTR--TPDIAQRAKKVRRVPGSSGHLHKTEDGDWEWSDDEMDEKSEEGKAAFSQEKSRRVKEENPEIAVSASTIPEQIQSLSVHDSQGPPNANEDYREASSCAVNLVLRLRNSRK--ELNDIRFEFTPGRDTADGVSQELFSAGLVDGHDVVIVAANLQKIVDDPKALKTLTFKLASGCDGSEIPDEVKLIGFAQL 542
BLAST of Serine/threonine-protein kinase OSR1 vs. UniProt/SwissProt
Match: sp|G5EEN4|GCK3_CAEEL (Germinal center kinase 3 OS=Caenorhabditis elegans OX=6239 GN=gck-3 PE=1 SV=1) HSP 1 Score: 324.324 bits (830), Expect = 6.359e-102 Identity = 165/343 (48.10%), Postives = 226/343 (65.89%), Query Frame = 2
Query: 146 WSNKREDYKINRSIGQGATSNVYEAECLPLNNRLCAMKIINLEKCNSSSLLEEIKREIKSMKNMKNENIVTYYASFVNGIELFIIMDVCQRGSLLDIIKR---TQSKRDITYGVFDESTIATILKDVLRGLTYIHENGLVHRDLKCGNLLVKDDGIIQIADFGVAAFLAAQPMHTTGASLDNK--RFTFVGTPCWMAPEVMQQVKGHNQKADIWSLGITAIELAAGQAPYAKYAPMKVLMLTLQNESPDIDTAASSCNQYSNYGQKYRKFSKACLNKDPAMRPSAKELLQSPFIKSKAKDRDSLIKVLLSE-DTLPFERQRSDENLCPEKTPTKAFSGEWNFD 1156
W + YK++ SIG GAT+ V+ A CLP N ++ A+K INLEKC +S ++E+ EI++M + N+V+YY SF+ EL+++M + GS+LDI+KR K +GV DE +IAT+L++VL+GL Y H NG +HRD+K GN+L+ DDG IQIADFGV+ +LA ++G L + R TFVGTPCWMAPEVM+QV+G++ KADIWSLGI AIELA G APY KY PMKVLMLTLQN+ P ++T A +QY YG+ ++ + CL KDPA RP+A ELL+ F K K KD+ L+ L+ ++P S + + K A G W F+
Sbjct: 101 WPTEPSAYKLDESIGVGATATVFTAYCLPRNEKV-AIKCINLEKCQTS--VDELSHEIQAMSQCNHPNVVSYYTSFIAQEELWVVMRLLNCGSMLDILKRKVKAIGKEQAQFGVLDEVSIATVLREVLKGLEYFHLNGQIHRDIKAGNILLADDGTIQIADFGVSGWLA-----SSGGDLSRQKVRHTFVGTPCWMAPEVMEQVQGYDFKADIWSLGILAIELATGTAPYHKYPPMKVLMLTLQNDPPTLETNAERKDQYKAYGKSFKTLIRDCLQKDPAKRPTASELLKYSFFK-KGKDKKYLVHTLIENLASVPVVAHHSSKKVASGKLRKDAH-GNWEFE 433 HSP 2 Score: 59.6918 bits (143), Expect = 4.610e-8 Identity = 38/101 (37.62%), Postives = 59/101 (58.42%), Query Frame = 2
Query: 1244 PISYRITLRKRNPKKNNELEDISFDYVIGKDSVELLVRELVEADLLDGCDLLLVAHNMSELV----ANPSVRERVFALNSP-PSTGVANEQELYGYAKVLL 1531
P + + LR RN ++ EL DI FDY D+VE + ELV A+L+D DL++VA N+ +L+ + R FALNS + + +E+ L G+A++ L
Sbjct: 496 PETLNMVLRVRNQQR--ELNDIKFDYTKSADTVEGIAHELVTAELIDCHDLVIVAANLQKLIDFAESKSDRRSITFALNSGVHANEIPDERTLTGFAQISL 594
BLAST of Serine/threonine-protein kinase OSR1 vs. UniProt/SwissProt
Match: sp|Q6P9R2|OXSR1_MOUSE (Serine/threonine-protein kinase OSR1 OS=Mus musculus OX=10090 GN=Oxsr1 PE=1 SV=1) HSP 1 Score: 317.39 bits (812), Expect = 3.769e-100 Identity = 163/316 (51.58%), Postives = 214/316 (67.72%), Query Frame = 2
Query: 146 WSNKREDYKINRSIGQGATSNVYEAECLPLNNRLCAMKIINLEKCNSSSLLEEIKREIKSMKNMKNENIVTYYASFVNGIELFIIMDVCQRGSLLDIIKRTQSKRDITYGVFDESTIATILKDVLRGLTYIHENGLVHRDLKCGNLLVKDDGIIQIADFGVAAFLAAQPMHTTGASLDNK-RFTFVGTPCWMAPEVMQQVKGHNQKADIWSLGITAIELAAGQAPYAKYAPMKVLMLTLQNESPDIDTAASSCNQYSNYGQKYRKFSKACLNKDPAMRPSAKELLQSPFIKSKAKDRDSLIKVLLSEDTLPFERQR 1090
WS R+DY++ IG GAT+ V A C P R+ A+K INLEKC +S ++E+ +EI++M + NIV+YY SFV EL+++M + GS+LDIIK +K + GV DE TIATIL++VL GL Y+H+NG +HRD+K GN+L+ +DG +QIADFGV+AFLA T G NK R TFVGTPCWMAPEVM+QV+G++ KADIWS GITAIELA G APY KY PMKVLMLTLQN+ P ++T YG+ +RK CL KDP RP+A ELL+ F + KAK+++ L + +L ER +
Sbjct: 10 WSINRDDYELQEVIGSGATAVVQAAYCAPKKERV-AIKRINLEKCQTS--MDELLKEIQAMSQCHHPNIVSYYTSFVVKDELWLVMKLLSGGSVLDIIKHIVAKGEHKSGVLDEPTIATILREVLEGLEYLHKNGQIHRDVKAGNILLGEDGSVQIADFGVSAFLA-----TGGDITRNKVRKTFVGTPCWMAPEVMEQVRGYDFKADIWSFGITAIELATGAAPYHKYPPMKVLMLTLQNDPPSLETGVQDKEMLKKYGKSFRKMISLCLQKDPEKRPTAAELLRHKFFQ-KAKNKEFLQEKILQRAPTISERSK 316 HSP 2 Score: 59.6918 bits (143), Expect = 4.859e-8 Identity = 39/100 (39.00%), Postives = 61/100 (61.00%), Query Frame = 2
Query: 1232 ENSEPISYRITLRKRNPKKNNELEDISFDYVIGKDSVELLVRELVEADLLDGCDLLLVAHNMSELVANP-SVRERVFALNSP-PSTGVANEQELYGYAKV 1525
E PIS + LR RN KK EL DI F++ G+D+ E + +EL+ A L+DG DL++VA N+ ++V P S R F L S + + ++ +L G+A++
Sbjct: 429 ETKIPIS--LVLRLRNSKK--ELNDIRFEFTPGRDTAEGVSQELISAGLVDGRDLVIVAANLQKIVEEPQSNRSVTFKLASGVEGSDIPDDGKLIGFAQL 524
BLAST of Serine/threonine-protein kinase OSR1 vs. TrEMBL
Match: A0A504YNK3 (Serine/threonine-protein kinase OSR1 OS=Fasciola gigantica OX=46835 GN=FGIG_03036 PE=4 SV=1) HSP 1 Score: 494.197 bits (1271), Expect = 2.129e-165 Identity = 243/370 (65.68%), Postives = 287/370 (77.57%), Query Frame = 2
Query: 113 NAVDGSNQTIVWSNKREDYKINRSIGQGATSNVYEAECLPLNNRLCAMKIINLEKCNSSSLLEEIKREIKSMKNMKNENIVTYYASFVNGIELFIIMDVCQRGSLLDIIKRTQSKRDITYGVFDESTIATILKDVLRGLTYIHENGLVHRDLKCGNLLVKDDGIIQIADFGVAAFLAAQPMHTTGASLDNKRFTFVGTPCWMAPEVMQQVKGHNQKADIWSLGITAIELAAGQAPYAKYAPMKVLMLTLQNESPDIDTAASSCNQYSNYGQKYRKFSKACLNKDPAMRPSAKELLQSPFIKSKAKDRDSLIKVLL-SEDTLPFERQRSDENLCPEKTPTKAFSGEWNFDLQPLGDHLNDIDNKESVDKTE 1219
N V + + W + ++ +SIGQGATS V+EA C P N+R CA+KIINLEKC++S+ LEEI REIKSMKNMKNENIV YYASFV+ EL I+MD+CQRGSLLD+IK TQSKRD++YGVFDE+TIATIL+DVLRGL YIHENGLVHRDLKCGNLLVKDDGIIQIADFGVA FLA QP+ TG S+D +RFTFVGTPCWMAPEVMQQ +G+NQKADIWSLGIT IE+A GQAPYAKYAPMKVLMLTLQN+ PDIDT A+ NQY NYGQK+RKF++ACL KDP R SA+ELL +IK+KAKDR+ L +VLL E P R + E+ K S EWNFD + +D++E D+ +
Sbjct: 8 NPVGVTEPAVQWPMTKSAFEFGKSIGQGATSVVFEALC-PANSRRCAIKIINLEKCSTSASLEEINREIKSMKNMKNENIVAYYASFVDATELCIVMDLCQRGSLLDVIKYTQSKRDVSYGVFDENTIATILRDVLRGLAYIHENGLVHRDLKCGNLLVKDDGIIQIADFGVAGFLATQPLTATG-SVDLRRFTFVGTPCWMAPEVMQQARGYNQKADIWSLGITTIEMATGQAPYAKYAPMKVLMLTLQNDPPDIDTVATVSNQYINYGQKFRKFTRACLLKDPGQRLSARELLGHTYIKAKAKDRELLCRVLLGGEIPPPVTRISKHSDDRTERRDPKNNSTEWNFDTIGRASSQHGLDSEEDSDEMD 375 HSP 2 Score: 136.346 bits (342), Expect = 3.331e-30 Identity = 82/122 (67.21%), Postives = 96/122 (78.69%), Query Frame = 2
Query: 1199 ESVDKTENETFENSEPI--SYRITLRKRNPKKNNELEDISFDYVIGKDSVELLVRELVEADLLDGCDLLLVAHNMSELVANPSVRERVFALNSPPSTG-VANEQELYGYAKVLLRFFGEPKP 1555
S+D E + E+ P SYRITLRKRN K+NNEL+DISF+YV GKDS ++L RELVEADLLDGCDLLLVAHNMSEL++NP+ RERVF LNSPP+ G V E EL+GYAKVL+R G P P
Sbjct: 483 HSLDNHEVLSGESDAPAGPSYRITLRKRNLKQNNELQDISFNYVPGKDSADVLARELVEADLLDGCDLLLVAHNMSELISNPAARERVFPLNSPPAPGQVPVESELHGYAKVLIRLVGSPVP 604
BLAST of Serine/threonine-protein kinase OSR1 vs. TrEMBL
Match: A0A4S2LUR6 (Protein kinase domain-containing protein OS=Opisthorchis felineus OX=147828 GN=CRM22_006110 PE=4 SV=1) HSP 1 Score: 492.656 bits (1267), Expect = 2.541e-165 Identity = 238/340 (70.00%), Postives = 273/340 (80.29%), Query Frame = 2
Query: 140 IVWSNKREDYKINRSIGQGATSNVYEAECLPLNNRLCAMKIINLEKCNSSSLLEEIKREIKSMKNMKNENIVTYYASFVNGIELFIIMDVCQRGSLLDIIKRTQSKRDITYGVFDESTIATILKDVLRGLTYIHENGLVHRDLKCGNLLVKDDGIIQIADFGVAAFLAAQPMHTTGASLDNKRFTFVGTPCWMAPEVMQQVKGHNQKADIWSLGITAIELAAGQAPYAKYAPMKVLMLTLQNESPDIDTAASSCNQYSNYGQKYRKFSKACLNKDPAMRPSAKELLQSPFIKSKAKDRDSLIKVLL-SEDTLPFERQRSDENLCPEKTPTKAFSGEWNFD 1156
+ W + Y +SIGQGATS V+EA C P+N R CA+KIINLEKC++S+ LEEI REIKSMKNMKNENIV YYASFV+ EL I+MD+CQRGSLLD+IK TQSKRDI+YGVFDE+TIATIL+DVLRGL YIHENGLVHRDLKCGNLLVKDDG+IQIADFGVA FLA QP+ T S+D +RFTFVGTPCWMAPEVMQQ +G+NQKADIWSLGIT IE+A GQAPYAKYAPMKVLMLTLQN+ PDIDT A+ NQY NYGQK+RKF++ACL KDP R SA+ELL +IK+KAKDR+ L +V+L E P R + EK K S EWNFD
Sbjct: 18 VQWPMTKSSYDFGKSIGQGATSTVFEASC-PVNGRKCAIKIINLEKCSTSASLEEINREIKSMKNMKNENIVAYYASFVDQTELCIVMDLCQRGSLLDVIKYTQSKRDISYGVFDENTIATILRDVLRGLAYIHENGLVHRDLKCGNLLVKDDGVIQIADFGVAGFLATQPLTATD-SVDLRRFTFVGTPCWMAPEVMQQARGYNQKADIWSLGITTIEMATGQAPYAKYAPMKVLMLTLQNDPPDIDTVATVSNQYINYGQKFRKFTRACLMKDPGQRLSARELLSHTYIKAKAKDRELLCRVMLGGEIPPPISRSNKHADDRSEKRGPKNNSTEWNFD 355 HSP 2 Score: 73.1738 bits (178), Expect = 9.298e-10 Identity = 33/41 (80.49%), Postives = 38/41 (92.68%), Query Frame = 2
Query: 1250 SYRITLRKRNPKKNNELEDISFDYVIGKDSVELLVRELVEA 1372
SYRITLRKRNPK+NNEL+DISF+YV GKDS ++L RELVEA
Sbjct: 491 SYRITLRKRNPKQNNELQDISFNYVPGKDSADVLARELVEA 531
BLAST of Serine/threonine-protein kinase OSR1 vs. TrEMBL
Match: A0A158QC04 (Protein kinase domain-containing protein OS=Hymenolepis diminuta OX=6216 GN=HDID_LOCUS773 PE=3 SV=1) HSP 1 Score: 488.804 bits (1257), Expect = 2.752e-165 Identity = 241/375 (64.27%), Postives = 286/375 (76.27%), Query Frame = 2
Query: 77 FSTLGLGTISDSNAVDGSNQTIVWSNKREDYKINRSIGQGATSNVYEAECLPLNNRLCAMKIINLEKCNSSSLLEEIKREIKSMKNMKNENIVTYYASFVNGIELFIIMDVCQRGSLLDIIKRTQSKRDITYGVFDESTIATILKDVLRGLTYIHENGLVHRDLKCGNLLVKDDGIIQIADFGVAAFLAAQPMHTTGASLDNKRFTFVGTPCWMAPEVMQQVKGHNQKADIWSLGITAIELAAGQAPYAKYAPMKVLMLTLQNESPDIDTAASSCNQYSNYGQKYRKFSKACLNKDPAMRPSAKELLQSPFIKSKAKDRDSLIKVLLSED--TLPFERQRSDENLCPEKTPTKAFSGEWNFDL-----QPLGDHL 1180
++L G+ +++N + W R Y+I +SIGQGATS V+EA C PLN R CAMKIINL+K N+S+ LEEI REIKSMKNMKNENIV YYASFV+ EL I+MD+CQRGSLLD+IK QSKRDITYGVFDE TIATILKDVLRGL YIHE GLVHRDLKCGNLLVKDDG+IQIADFGVA FLA+QP+ TG S+ +RFTFVGTPCWMAPEVMQQ G+N KAD+WS+GIT IE+A GQAPYAKY PMKVLMLTL+N+ PDIDT A+ NQY YG K+RKF+K+CL KDPA RP+AKELL ++KSKAKDR+ L +VLLS + T P ++ R E+ ++ F+ EW+FD P G H
Sbjct: 3 MTSLNFGSFAETN--------VQWPVVRSAYEIVKSIGQGATSTVHEAFCKPLN-RKCAMKIINLDKSNTSASLEEINREIKSMKNMKNENIVAYYASFVDKTELCIVMDLCQRGSLLDVIKFIQSKRDITYGVFDEYTIATILKDVLRGLAYIHEGGLVHRDLKCGNLLVKDDGVIQIADFGVAGFLASQPLSETG-SMGPRRFTFVGTPCWMAPEVMQQTGGYNHKADVWSIGITTIEMATGQAPYAKYTPMKVLMLTLKNDPPDIDTGATVSNQYVEYGHKFRKFTKSCLTKDPAQRPTAKELLSHSYVKSKAKDRELLCRVLLSGEVPTPPLKQNRHHEDRSEKRDKANVFT-EWDFDTIGRGGGPSGSHF 366
BLAST of Serine/threonine-protein kinase OSR1 vs. TrEMBL
Match: A0A4E0RBM9 (Serine/threonine-protein kinase OSR1 OS=Fasciola hepatica OX=6192 GN=D915_005022 PE=4 SV=1) HSP 1 Score: 493.812 bits (1270), Expect = 2.762e-165 Identity = 243/370 (65.68%), Postives = 287/370 (77.57%), Query Frame = 2
Query: 113 NAVDGSNQTIVWSNKREDYKINRSIGQGATSNVYEAECLPLNNRLCAMKIINLEKCNSSSLLEEIKREIKSMKNMKNENIVTYYASFVNGIELFIIMDVCQRGSLLDIIKRTQSKRDITYGVFDESTIATILKDVLRGLTYIHENGLVHRDLKCGNLLVKDDGIIQIADFGVAAFLAAQPMHTTGASLDNKRFTFVGTPCWMAPEVMQQVKGHNQKADIWSLGITAIELAAGQAPYAKYAPMKVLMLTLQNESPDIDTAASSCNQYSNYGQKYRKFSKACLNKDPAMRPSAKELLQSPFIKSKAKDRDSLIKVLL-SEDTLPFERQRSDENLCPEKTPTKAFSGEWNFDLQPLGDHLNDIDNKESVDKTE 1219
N V + + W + ++ +SIGQGATS V+EA C P N+R CA+KIINLEKC++S+ LEEI REIKSMKNMKNENIV YYASFV+ EL I+MD+CQRGSLLD+IK TQSKRD++YGVFDE+TIATIL+DVLRGL YIHENGLVHRDLKCGNLLVKDDGIIQIADFGVA FLA QP+ TG S+D +RFTFVGTPCWMAPEVMQQ +G+NQKADIWSLGIT IE+A GQAPYAKYAPMKVLMLTLQN+ PDIDT A+ NQY NYGQK+RKF++ACL KDP R SA+ELL +IK+KAKDR+ L +VLL E P R + E+ K S EWNFD + +D++E D+ +
Sbjct: 8 NPVGVTEPAVQWPMTKSAFEFGKSIGQGATSVVFEALC-PANSRRCAIKIINLEKCSTSASLEEINREIKSMKNMKNENIVAYYASFVDATELCIVMDLCQRGSLLDVIKYTQSKRDVSYGVFDENTIATILRDVLRGLAYIHENGLVHRDLKCGNLLVKDDGIIQIADFGVAGFLATQPLTATG-SVDLRRFTFVGTPCWMAPEVMQQARGYNQKADIWSLGITTIEMATGQAPYAKYAPMKVLMLTLQNDPPDIDTVATVSNQYINYGQKFRKFTRACLLKDPGQRLSARELLGHTYIKAKAKDRELLCRVLLGGEIPPPVTRISKHSDDRTERRDPKNNSTEWNFDTIGRASSQHGLDSEEDSDEMD 375 HSP 2 Score: 136.346 bits (342), Expect = 3.656e-30 Identity = 82/122 (67.21%), Postives = 96/122 (78.69%), Query Frame = 2
Query: 1199 ESVDKTENETFENSEPI--SYRITLRKRNPKKNNELEDISFDYVIGKDSVELLVRELVEADLLDGCDLLLVAHNMSELVANPSVRERVFALNSPPSTG-VANEQELYGYAKVLLRFFGEPKP 1555
S+D E + E+ P SYRITLRKRN K+NNEL+DISF+YV GKDS ++L RELVEADLLDGCDLLLVAHNMSEL++NP+ RERVF LNSPP+ G V E EL+GYAKVL+R G P P
Sbjct: 483 HSLDNHEVLSGESDAPAGPSYRITLRKRNLKQNNELQDISFNYVPGKDSADVLARELVEADLLDGCDLLLVAHNMSELISNPAARERVFPLNSPPAPGQVPVESELHGYAKVLIRLVGSPVP 604
BLAST of Serine/threonine-protein kinase OSR1 vs. TrEMBL
Match: A0A4S2LV50 (Protein kinase domain-containing protein OS=Opisthorchis felineus OX=147828 GN=CRM22_006110 PE=4 SV=1) HSP 1 Score: 493.041 bits (1268), Expect = 4.084e-165 Identity = 238/340 (70.00%), Postives = 273/340 (80.29%), Query Frame = 2
Query: 140 IVWSNKREDYKINRSIGQGATSNVYEAECLPLNNRLCAMKIINLEKCNSSSLLEEIKREIKSMKNMKNENIVTYYASFVNGIELFIIMDVCQRGSLLDIIKRTQSKRDITYGVFDESTIATILKDVLRGLTYIHENGLVHRDLKCGNLLVKDDGIIQIADFGVAAFLAAQPMHTTGASLDNKRFTFVGTPCWMAPEVMQQVKGHNQKADIWSLGITAIELAAGQAPYAKYAPMKVLMLTLQNESPDIDTAASSCNQYSNYGQKYRKFSKACLNKDPAMRPSAKELLQSPFIKSKAKDRDSLIKVLL-SEDTLPFERQRSDENLCPEKTPTKAFSGEWNFD 1156
+ W + Y +SIGQGATS V+EA C P+N R CA+KIINLEKC++S+ LEEI REIKSMKNMKNENIV YYASFV+ EL I+MD+CQRGSLLD+IK TQSKRDI+YGVFDE+TIATIL+DVLRGL YIHENGLVHRDLKCGNLLVKDDG+IQIADFGVA FLA QP+ T S+D +RFTFVGTPCWMAPEVMQQ +G+NQKADIWSLGIT IE+A GQAPYAKYAPMKVLMLTLQN+ PDIDT A+ NQY NYGQK+RKF++ACL KDP R SA+ELL +IK+KAKDR+ L +V+L E P R + EK K S EWNFD
Sbjct: 18 VQWPMTKSSYDFGKSIGQGATSTVFEASC-PVNGRKCAIKIINLEKCSTSASLEEINREIKSMKNMKNENIVAYYASFVDQTELCIVMDLCQRGSLLDVIKYTQSKRDISYGVFDENTIATILRDVLRGLAYIHENGLVHRDLKCGNLLVKDDGVIQIADFGVAGFLATQPLTATD-SVDLRRFTFVGTPCWMAPEVMQQARGYNQKADIWSLGITTIEMATGQAPYAKYAPMKVLMLTLQNDPPDIDTVATVSNQYINYGQKFRKFTRACLMKDPGQRLSARELLSHTYIKAKAKDRELLCRVMLGGEIPPPISRSNKHADDRSEKRGPKNNSTEWNFD 355 HSP 2 Score: 139.043 bits (349), Expect = 4.087e-31 Identity = 78/103 (75.73%), Postives = 88/103 (85.44%), Query Frame = 2
Query: 1250 SYRITLRKRNPKKNNELEDISFDYVIGKDSVELLVRELVEADLLDGCDLLLVAHNMSELVANPSVRERVFALNSPPSTG-VANEQELYGYAKVLLRFFGEPKP 1555
SYRITLRKRNPK+NNEL+DISF+YV GKDS ++L RELVEADLLDGCDLLLVAHNMSEL++NP RERVF LNSPP+ G V E EL+GYAKVL+R G P P
Sbjct: 491 SYRITLRKRNPKQNNELQDISFNYVPGKDSADVLARELVEADLLDGCDLLLVAHNMSELISNPGQRERVFPLNSPPAPGQVPVESELHGYAKVLIRLVGSPTP 593
BLAST of Serine/threonine-protein kinase OSR1 vs. Ensembl Cavefish
Match: stk39 (serine/threonine kinase 39 [Source:NCBI gene;Acc:103028154]) HSP 1 Score: 345.895 bits (886), Expect = 2.401e-112 Identity = 211/500 (42.20%), Postives = 301/500 (60.20%), Query Frame = 2
Query: 137 TIVWSNKREDYKINRSIGQGATSNVYEAECLPLNNRLCAMKIINLEKCNSSSLLEEIKREIKSMKNMKNENIVTYYASFVNGIELFIIMDVCQRGSLLDIIKRTQSKRDITYGVFDESTIATILKDVLRGLTYIHENGLVHRDLKCGNLLVKDDGIIQIADFGVAAFLAAQPMHTTGASLDNK-RFTFVGTPCWMAPEVMQQVKGHNQKADIWSLGITAIELAAGQAPYAKYAPMKVLMLTLQNESPDIDTAASSCNQYSNYGQKYRKFSKACLNKDPAMRPSAKELLQSPFIKSKAKDRDSLIKVLLSEDTLPFERQRSDE-NLCPEKTP--TKAFSGEWNFDLQPLGDHLNDIDNKESVD-------KTENETFE---NSEPI---------------------SYRITLRKRNPKKNNELEDISFDYVIGKDSVELLVRELVEADLLDGCDLLLVAHNMSELVANP-SVRERVFALNSP-PSTGVANEQELYGYAKV 1525
T W +E Y++ IG GAT+ V A C P R+ A+K INLEKC +S +EE+ +EI++M + N+VTYY SFV EL+++M + GS+LDIIK T S+ + GV DE TIA+ILK+VL GL Y+H+NG +HRD+K GN+L+ +DG +QIADFGV+AFLA T G +K R TFVGTPCWMAPEVM+QV+G++ KADIWS GITAIELA G APY +Y PMKVLMLTLQN+ P ++T YG+ +RK CL KDPA RP+A ELL+ F + KAK+R+ L++ LL + P QR+ + P + K G+W + + + + K +V+ K EN+ E N+ PI + + LR RN +K EL DI F++ G+D+ + + +EL A L++G D+++VA N+ ++V +P + + F L S ST + +E +L G+A++
Sbjct: 19 TTSWPIVKEAYELQEVIGSGATAVVQAALCTPRQERV-AVKRINLEKCQTS--MEELLKEIQAMSQCNHPNVVTYYTSFVVKDELWLVMKLLSGGSVLDIIKHTCSRGEHKNGVLDEPTIASILKEVLEGLDYLHKNGQIHRDVKAGNILLGEDGSVQIADFGVSAFLA-----TGGDVTRHKVRKTFVGTPCWMAPEVMEQVRGYDFKADIWSFGITAIELATGSAPYHRYPPMKVLMLTLQNDPPMLETGVEDKEMLKKYGKSFRKLITLCLQKDPAKRPTASELLKCKFFQ-KAKNREYLVEKLLCKG--PNISQRAKKVRRVPGSSGHLHKTEDGDWEWSDDEMDERSE--EGKAAVNQGRSRRVKEENQDGEVNANNVPIESLSIQHPQVQPLEKNPNTVGAVNMVLRLRNSRK--ELNDIRFEFTPGQDTADGVSQELFSAGLVNGHDVIVVAANLQKIVEDPVTYKVLTFKLASGCDSTEIPDEVKLIGFAQL 503
BLAST of Serine/threonine-protein kinase OSR1 vs. Ensembl Cavefish
Match: oxsr1b (oxidative stress responsive kinase 1 [Source:NCBI gene;Acc:103043241]) HSP 1 Score: 340.887 bits (873), Expect = 8.533e-111 Identity = 204/479 (42.59%), Postives = 293/479 (61.17%), Query Frame = 2
Query: 146 WSNKREDYKINRSIGQGATSNVYEAECLPLNNRLCAMKIINLEKCNSSSLLEEIKREIKSMKNMKNENIVTYYASFVNGIELFIIMDVCQRGSLLDIIKRTQSKRDITYGVFDESTIATILKDVLRGLTYIHENGLVHRDLKCGNLLVKDDGIIQIADFGVAAFLAAQPMHTTGASLDNK-RFTFVGTPCWMAPEVMQQVKGHNQKADIWSLGITAIELAAGQAPYAKYAPMKVLMLTLQNESPDIDTAASSCNQYSNYGQKYRKFSKACLNKDPAMRPSAKELLQSPFIKSKAKDRDSLIKVLLSEDTLPFERQRSDENLCPEKTPT--KAFSGEWNFD--------------LQPLGDHLNDIDNKESVDKTENETFENSEPISYRITLRKRNPKKNNELEDISFDYVIGKDSVELLVRELVEADLLDGCDLLLVAHNMSELVANPSVRERV-FALNSP-PSTGVANEQELYGYAKV 1525
WS ++DY++ IG GAT+ V A C+P ++ A+K INLEKC +S ++E+ +EI++M + NIV+YY SFV EL+++M + GS+LD+IK S+ + GV DE++IATILK+VL+GL Y+H+NG +HRDLK GN+L+ +DG +QIADFGV+AFL+ T G NK R TFVGTPCWMAPEVM+QVKG++ KADIWS GITAIELA G APY KY PMKVLMLTLQN+ P ++T + YG+ RK CL KDP RP++ ELL+ F + KAK+ + L + LL + ER + + P + K GEW + + L L+ + K V K+ + + + L RN KK EL DI F+++ G+D+ + + +ELV A L+DG DL++VA N+ ++V P + V F L S + + ++ +L G+A++
Sbjct: 10 WSICKDDYELQEVIGSGATAVVQAAYCVPRKEKV-AIKRINLEKCQTS--MDELLKEIQAMSQCHHPNIVSYYTSFVVKDELWLVMKLLSGGSVLDVIKHIISRGEHKTGVLDEASIATILKEVLQGLEYLHKNGQIHRDLKAGNILLGEDGSVQIADFGVSAFLS-----TGGDITRNKVRKTFVGTPCWMAPEVMEQVKGYDFKADIWSFGITAIELATGAAPYHKYPPMKVLMLTLQNDPPTLETGITDKEMVKKYGKSLRKMVSLCLQKDPEKRPTSLELLKHKFFQ-KAKNNEFLQEKLLQKAPTISERSKKVRRV-PGSSGRLHKTEDGEWEWSDDELDEESEEGKAAVAALRVKLDLLFLKAQVCKSLIRKASD----LFSLFLFARNLKK--ELNDIRFEFMPGRDTADGVSQELVSAGLVDGRDLVIVAANLQKIVDEPQTNKNVTFKLASGVEGSEIPDDVKLMGFAQL 472
BLAST of Serine/threonine-protein kinase OSR1 vs. Ensembl Cavefish
Match: stk39 (serine/threonine kinase 39 [Source:NCBI gene;Acc:103028154]) HSP 1 Score: 340.887 bits (873), Expect = 9.770e-110 Identity = 202/472 (42.80%), Postives = 284/472 (60.17%), Query Frame = 2
Query: 137 TIVWSNKREDYKINRSIGQGATSNVYEAECLPLNNRLCAMKIINLEKCNSSSLLEEIKREIKSMKNMKNENIVTYYASFVNGIELFIIMDVCQRGSLLDIIKRTQSKRDITYGVFDESTIATILKDVLRGLTYIHENGLVHRDLKCGNLLVKDDGIIQIADFGVAAFLAAQPMHTTGASLDNK-RFTFVGTPCWMAPEVMQQVKGHNQKADIWSLGITAIELAAGQAPYAKYAPMKVLMLTLQNESPDIDTAASSCNQYSNYGQKYRKFSKACLNKDPAMRPSAKELLQSPFIKSKAKDRDSLIKVLLSEDTLPFERQRSDENLCPEKTPT------KAFSGEWNFDLQPLGDHLNDIDNKESVD-------KTENETFE---NSEPI---------------------SYRITLRKRNPKKNNELEDISFDYVIGKDSVELLVRELVEADLLDGCDLLLVAHNMSELVANP 1438
T W +E Y++ IG GAT+ V A C P R+ A+K INLEKC +S +EE+ +EI++M + N+VTYY SFV EL+++M + GS+LDIIK T S+ + GV DE TIA+ILK+VL GL Y+H+NG +HRD+K GN+L+ +DG +QIADFGV+AFLA T G +K R TFVGTPCWMAPEVM+QV+G++ KADIWS GITAIELA G APY +Y PMKVLMLTLQN+ P ++T YG+ +RK CL KDPA RP+A ELL+ F + KAK+R+ L++ LL + P QR+ + + P K G+W + + + + K +V+ K EN+ E N+ PI + + LR RN +K EL DI F++ G+D+ + + +EL A L++G D+++VA N+ ++V +P
Sbjct: 19 TTSWPIVKEAYELQEVIGSGATAVVQAALCTPRQERV-AVKRINLEKCQTS--MEELLKEIQAMSQCNHPNVVTYYTSFVVKDELWLVMKLLSGGSVLDIIKHTCSRGEHKNGVLDEPTIASILKEVLEGLDYLHKNGQIHRDVKAGNILLGEDGSVQIADFGVSAFLA-----TGGDVTRHKVRKTFVGTPCWMAPEVMEQVRGYDFKADIWSFGITAIELATGSAPYHRYPPMKVLMLTLQNDPPMLETGVEDKEMLKKYGKSFRKLITLCLQKDPAKRPTASELLKCKFFQ-KAKNREYLVEKLLCKG--PNISQRAKKV---RRVPGSSGHLHKTEDGDWEWSDDEMDERSE--EGKAAVNQGRSRRVKEENQDGEVNANNVPIESLSIQHPQVQPLEKNPNTVGAVNMVLRLRNSRK--ELNDIRFEFTPGQDTADGVSQELFSAGLVNGHDVIVVAANLQKIVEDP 472
BLAST of Serine/threonine-protein kinase OSR1 vs. Ensembl Cavefish
Match: oxsr1b (oxidative stress responsive kinase 1 [Source:NCBI gene;Acc:103043241]) HSP 1 Score: 338.191 bits (866), Expect = 2.728e-109 Identity = 206/517 (39.85%), Postives = 297/517 (57.45%), Query Frame = 2
Query: 146 WSNKREDYKINRSIGQGATSNVYEAECLPLNNRLCAMKIINLEKCNSSSLLEEIKREIKSMKNMKNENIVTYYASFVNGIELFIIMDVCQRGSLLDIIKRTQSKRDITYGVFDESTIATILKDVLRGLTYIHENGLVHRDLKCGNLLVKDDGIIQIADFGVAAFLAAQPMHTTGASLDNK-RFTFVGTPCWMAPEVMQQVKGHNQKADIWSLGITAIELAAGQAPYAKYAPMKVLMLTLQNESPDIDTAASSCNQYSNYGQKYRKFSKACLNKDPAMRPSAKELLQSPFIKSKAKDRDSLIKVLLSEDTLPFERQRSDENLCPEKTPT--KAFSGEWNF--------------------------------DLQPLGDHLN-DIDNKESVDKTENETFENSE--PIS-----------------YRITLRKRNPKKNNELEDISFDYVIGKDSVELLVRELVEADLLDGCDLLLVAHNMSELVANPSVRERV-FALNSP-PSTGVANEQELYGYAKV 1525
WS ++DY++ IG GAT+ V A C+P ++ A+K INLEKC +S ++E+ +EI++M + NIV+YY SFV EL+++M + GS+LD+IK S+ + GV DE++IATILK+VL+GL Y+H+NG +HRDLK GN+L+ +DG +QIADFGV+AFL+ T G NK R TFVGTPCWMAPEVM+QVKG++ KADIWS GITAIELA G APY KY PMKVLMLTLQN+ P ++T + YG+ RK CL KDP RP++ ELL+ F + KAK+ + L + LL + ER + + P + K GEW + +P HL + V ++ + ++ P+S + LR RN KK EL DI F+++ G+D+ + + +ELV A L+DG DL++VA N+ ++V P + V F L S + + ++ +L G+A++
Sbjct: 10 WSICKDDYELQEVIGSGATAVVQAAYCVPRKEKV-AIKRINLEKCQTS--MDELLKEIQAMSQCHHPNIVSYYTSFVVKDELWLVMKLLSGGSVLDVIKHIISRGEHKTGVLDEASIATILKEVLQGLEYLHKNGQIHRDLKAGNILLGEDGSVQIADFGVSAFLS-----TGGDITRNKVRKTFVGTPCWMAPEVMEQVKGYDFKADIWSFGITAIELATGAAPYHKYPPMKVLMLTLQNDPPTLETGITDKEMVKKYGKSLRKMVSLCLQKDPEKRPTSLELLKHKFFQ-KAKNNEFLQEKLLQKAPTISERSKKVRRV-PGSSGRLHKTEDGEWEWSDDELDEESEEGKAAVAALRSPRVKEGSQNSEPTEPFSSHLQPGVPGPAEVPQSGGQPSAPAQALPVSTNPAQAPAPASDASNSPISLVLRLRNLKK--ELNDIRFEFMPGRDTADGVSQELVSAGLVDGRDLVIVAANLQKIVDEPQTNKNVTFKLASGVEGSEIPDDVKLMGFAQL 514
BLAST of Serine/threonine-protein kinase OSR1 vs. Ensembl Cavefish
Match: stk39 (serine/threonine kinase 39 [Source:NCBI gene;Acc:103028154]) HSP 1 Score: 317.39 bits (812), Expect = 6.296e-101 Identity = 163/308 (52.92%), Postives = 213/308 (69.16%), Query Frame = 2
Query: 137 TIVWSNKREDYKINRSIGQGATSNVYEAECLPLNNRLCAMKIINLEKCNSSSLLEEIKREIKSMKNMKNENIVTYYASFVNGIELFIIMDVCQRGSLLDIIKRTQSKRDITYGVFDESTIATILKDVLRGLTYIHENGLVHRDLKCGNLLVKDDGIIQIADFGVAAFLAAQPMHTTGASLDNK-RFTFVGTPCWMAPEVMQQVKGHNQKADIWSLGITAIELAAGQAPYAKYAPMKVLMLTLQNESPDIDTAASSCNQYSNYGQKYRKFSKACLNKDPAMRPSAKELLQSPFIKSKAKDRDSLIKVLL 1057
T W +E Y++ IG GAT+ V A C P R+ A+K INLEKC +S +EE+ +EI++M + N+VTYY SFV EL+++M + GS+LDIIK T S+ + GV DE TIA+ILK+VL GL Y+H+NG +HRD+K GN+L+ +DG +QIADFGV+AFLA T G +K R TFVGTPCWMAPEVM+QV+G++ KADIWS GITAIELA G APY +Y PMKVLMLTLQN+ P ++T YG+ +RK CL KDPA RP+A ELL+ F + KAK+R+ L++ LL
Sbjct: 19 TTSWPIVKEAYELQEVIGSGATAVVQAALCTPRQERV-AVKRINLEKCQTS--MEELLKEIQAMSQCNHPNVVTYYTSFVVKDELWLVMKLLSGGSVLDIIKHTCSRGEHKNGVLDEPTIASILKEVLEGLDYLHKNGQIHRDVKAGNILLGEDGSVQIADFGVSAFLA-----TGGDVTRHKVRKTFVGTPCWMAPEVMEQVRGYDFKADIWSFGITAIELATGSAPYHRYPPMKVLMLTLQNDPPMLETGVEDKEMLKKYGKSFRKLITLCLQKDPAKRPTASELLKCKFFQ-KAKNREYLVEKLL 317
BLAST of Serine/threonine-protein kinase OSR1 vs. Ensembl Sea Lamprey
Match: stk39 (serine threonine kinase 39 [Source:ZFIN;Acc:ZDB-GENE-140106-194]) HSP 1 Score: 233.417 bits (594), Expect = 1.260e-71 Identity = 118/207 (57.00%), Postives = 147/207 (71.01%), Query Frame = 2
Query: 476 VFDESTIATILKDVLRGLTYIHENGLVHRDLKCGNLLVKDDGIIQIADFGVAAFLAAQPMHTTGASLDNK-RFTFVGTPCWMAPEVMQQVKGHNQKADIWSLGITAIELAAGQAPYAKYAPMKVLMLTLQNESPDIDTAASSCNQYSNYGQKYRKFSKACLNKDPAMRPSAKELLQSPFIKSKAKDRDSLIKVLLSEDTLPFERQRS 1093
V +E IA+ILK+VL GL Y+H NG +HRD+K GN+L+ +DG IQIADFGV+AFLA T G NK R TFVGTPCWMAPEVM+QV+G++ KADIWS GITA+ELA+G APY KY PMKVLMLTLQN+ P ++T YG+ +RK CL KDPA RP+A ELL+S F + KAK+++ L + LL + P QRS
Sbjct: 1 VLEEPVIASILKEVLEGLDYLHRNGQIHRDVKAGNILLGEDGTIQIADFGVSAFLA-----TGGDVTRNKVRKTFVGTPCWMAPEVMEQVRGYDFKADIWSFGITAMELASGAAPYHKYPPMKVLMLTLQNDPPTLETGVEDKEMVKKYGKSFRKLISQCLQKDPAKRPTAAELLKSKFFQ-KAKNKEYLAEKLLHK--APTITQRS 199
BLAST of Serine/threonine-protein kinase OSR1 vs. Ensembl Sea Lamprey
Match: stk25a (serine/threonine kinase 25a [Source:ZFIN;Acc:ZDB-GENE-041010-92]) HSP 1 Score: 194.512 bits (493), Expect = 4.239e-56 Identity = 114/307 (37.13%), Postives = 176/307 (57.33%), Query Frame = 2
Query: 149 SNKREDYKINRSIGQGATSNVYEAECLPLNNR---LCAMKIINLEKCNSSSLLEEIKREIKSMKNMKNENIVTYYASFVNGIELFIIMDVCQRGSLLDIIKRTQSKRDITYGVFDESTIATILKDVLRGLTYIHENGLVHRDLK--CGNLLVKDDGIIQIADFGVAAFLAAQPMHTTGASLDNKRFTFVGTPCWMAPEVMQQVKGHNQKADIWSLGITAIELAAGQAPYAKYAPMKVLMLTLQNESPDIDTAASSCNQYSNYGQKYRKFSKACLNKDPAMRPSAKELLQSPFIKSKAKDRDSLIKVL 1054
++ E + IG+G+ V++ ++NR + A+KII+LE+ + +EI + + + Y+ S++ G +L+IIM+ GS LD+IK G +E IATIL+++L+GL Y+H +HRD+K N+L+ + G +++ADFGVA L + KR TFVGTP WMAPEV++Q ++ KADIWSLGITAIELA G+ P ++ PM+VL L +N P ++ NY + +++F +CLNKDP RP+AKELL+ FI+ AK L +++
Sbjct: 20 ADPEELFTKQERIGKGSFGEVFKG----IDNRTKEVVAIKIIDLEEAEDEIEDIQ--QEITVLSQCDSPYVTHYFGSYLKGTKLWIIMEYLGGGSALDLIKP---------GPLEEHQIATILREILKGLDYLHSERKIHRDIKGPAANVLLSEQGDVKLADFGVAGQLTDTQI---------KRNTFVGTPFWMAPEVIKQ-SAYDFKADIWSLGITAIELAKGEPPNSELHPMRVLFLIPKNNPPTLE---------GNYSKAFKEFVDSCLNKDPQFRPTAKELLKHKFIQRSAKKTSYLTELI 292
BLAST of Serine/threonine-protein kinase OSR1 vs. Ensembl Sea Lamprey
Match: MAP4K3 (mitogen-activated protein kinase kinase kinase kinase 3 [Source:HGNC Symbol;Acc:HGNC:6865]) HSP 1 Score: 174.096 bits (440), Expect = 2.069e-46 Identity = 106/305 (34.75%), Postives = 169/305 (55.41%), Query Frame = 2
Query: 158 REDYKINRSIGQGATSNVYEAECLPLNNRLCAMKIINLEKCNSSSLLEEIKREIKSMKNMKNENIVTYYASFVNGIELFIIMDVCQRGSLLDIIKRTQSKRDITYGVFDESTIATILKDVLRGLTYIHENGLVHRDLKCGNLLVKDDGIIQIADFGVAAFLAAQPMHTTGASLDNKRFTFVGTPCWMAPEV--MQQVKGHNQKADIWSLGITAIELAAGQAPYAKYAPMKVLMLTLQN--ESPDIDTAASSCNQYSNYGQKYRKFSKACLNKDPAMRPSAKELLQSPFIK---SKAKDRDSLIKV 1051
+ED+++ +G G +V++A + L A+KII LE + S+ I++EI MK K+ NIV YY S++ +L+I M+ C GSL DI T G E IA + ++ L+GL Y+H G +HRD+K N+L+ DDG +++ADFGV+A + A KR +F+GTP WMAPEV +++ G+N + D+W++GITAIELA Q P PM+ L L ++ + P + + + F K L K+P RP+A+++L +++ S+A+ + L +V
Sbjct: 11 QEDFELAERLGSGTYGDVHKARNVQ-TGELVAIKIIKLEPGDDFSV---IQQEIVMMKECKHTNIVAYYGSYLRHDKLWICMEHCGGGSLQDIYHVT--------GPLTERQIAYVTRETLQGLAYLHSEGKMHRDIKGANILLTDDGDVKLADFGVSAQITAT---------IAKRKSFIGTPYWMAPEVAAVERKGGYNHQCDVWAVGITAIELAELQPPMFDLHPMRALFLMSKSGFQPPKL-------RDKQKWSPVFHNFIKMALTKNPKKRPTAEKMLTHSYVQQPLSRAQALELLERV 287
BLAST of Serine/threonine-protein kinase OSR1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000010511.1 (pep scaffold:Pmarinus_7.0:GL476756:358747:414819:1 gene:ENSPMAG00000009510.1 transcript:ENSPMAT00000010511.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 160.614 bits (405), Expect = 8.535e-42 Identity = 94/260 (36.15%), Postives = 145/260 (55.77%), Query Frame = 2
Query: 245 LCAMKIINLEKCNSSSLLEEIKREIKSMKNMKNENIVTYYASFVNGIELFIIMDVCQRGSLLDIIKRTQSKRDITYGVFDESTIATILKDVLRGLTYIHENGLVHRDLKCGNLLVKDDGIIQIADFGVAAFLAAQPMHTTGASLDNKRFTFVGTPCWMAPEV--MQQVKGHNQKADIWSLGITAIELAAGQAPYAKYAPMKVLMLTLQN--ESPDIDTAASSCNQYSNYGQKYRKFSKACLNKDPAMRPSAKELLQSPFI 1012
L A+K+I LE + ++ I++EI M+ ++ NIV Y+ S++ +L+I M+ C GSL DI T G E IA + ++ L+GL Y+H +HRD+K N+L+ D G +++ADFGV+A + A KR +F+GTP WMAPEV +++ G+NQ+ D+W++GITAIELA Q P PM+ L L ++ + P + + + F K L K+P RP+A +LLQ PF+
Sbjct: 11 LSAIKVIKLESGDDFTV---IQQEIIMMQECQHINIVAYFGSYLRWDKLWICMEYCGGGSLQDIYHVT--------GPLSERQIAYVSRETLKGLAYLHSKCKMHRDIKGANILLTDHGEVKLADFGVSAQITAT---------IAKRMSFIGTPYWMAPEVAAVERKGGYNQQCDVWAVGITAIELAELQPPMFDLHPMRALFLMSKSNFQPPRLKDKV-------KWSGIFHNFIKQSLIKNPKKRPTADKLLQDPFV 243
BLAST of Serine/threonine-protein kinase OSR1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000169.1 (pep scaffold:Pmarinus_7.0:GL478331:850:46844:1 gene:ENSPMAG00000000147.1 transcript:ENSPMAT00000000169.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 152.14 bits (383), Expect = 3.767e-39 Identity = 89/281 (31.67%), Postives = 158/281 (56.23%), Query Frame = 2
Query: 242 RLCAMKIINLEKCNSSSLLEEIKREIKSMKNMKNE-NIVTYYASFV------NGIELFIIMDVCQRGSLLDIIKRTQSKRDITYGVFDESTIATILKDVLRGLTYIHENGLVHRDLKCGNLLVKDDGIIQIADFGVAAFLAAQPMHTTGASLDNKRFTFVGTPCWMAPEVM----QQVKGHNQKADIWSLGITAIELAAGQAPYAKYAPMKVLMLTLQNESPDIDTAASSCNQYSNYGQKYRKFSKACLNKDPAMRPSAKELLQSPFIKSKAKDRDSLIKV 1051
+L A+K++++ + EEIK EI +K + NI TYY +F+ + +L+++M+ C GS+ D++K T+ E IA I +++LRGL+++H + ++HRD+K N+L+ ++ +++ DFGV+A L T G +R TF+GTP WMAPEV+ ++ ++D+WSLG+TAIE+A G P PM+ L L +N P + + + +++ F+++CL K+ R ++LL+ PFI+ + +R I++
Sbjct: 9 QLAAIKVMDV----TEDEEEEIKLEINMLKKYSHHRNIATYYGAFIKKSPPGHDDQLWLVMEFCGAGSVTDLVKNTKG------NSLKEDWIAYICREILRGLSHLHAHRVIHRDIKGQNVLLTENAEVKLVDFGVSAQLD----RTVG-----RRNTFIGTPYWMAPEVIACDENPDATYDYRSDLWSLGVTAIEMAEGAPPLCDMHPMRALFLIPRNPPPRLKS--------KKWSKRFLSFAESCLVKNYLQRLPTEQLLKHPFIREQPNERQVRIQL 262
BLAST of Serine/threonine-protein kinase OSR1 vs. Ensembl Yeast
Match: SPS1 (Putative protein serine/threonine kinase; localizes to the nucleus and cytoplasm; required for efficient spore packaging, prospore membrane development and closure and localization of enzymes involved in spore wall synthesis; interacts with and required for Ssp1p phosphorylation and turnover; member of the GCKIII subfamily of STE20 kinases; multiply phosphorylated on S/T residues; interacts with 14-3-3 proteins, Bmh1p and Bmh2p; expressed at the end of meiosis [Source:SGD;Acc:S000002931]) HSP 1 Score: 172.555 bits (436), Expect = 9.913e-48 Identity = 101/285 (35.44%), Postives = 156/285 (54.74%), Query Frame = 2
Query: 167 YKINRSIGQGATSNVYEAECLPLNNRLCAMKIINLEKCNSSSLLEEIKREIKSMKNMKNENIVTYYASFVNGIELFIIMDVCQRGSLLDIIKRTQSKRDITYGVFDESTIATILKDVLRGLTYIHENGLVHRDLKCGNLLVKDDGIIQIADFGVAAFLAAQPMHTTGASLDNKRFTFVGTPCWMAPEVM-QQVKGHNQKADIWSLGITAIELAAGQAPYAKYAPMKVLMLTLQNESPDIDTAASSCNQYSNYGQKYRKFSKACLNKDPAMRPSAKELLQSPFIKS 1018
Y I IG+G +VY+A + + A+K++NLE +S +E + +EI + +K+ I Y A+ + + ++I+M+ C GS D++KR+ E ++ I+ +V GL Y+HE +HRD+K N+L+ ++G++++ DFGV+ + + KR TFVGTP WMAPEV+ +V G+N+KADIWSLGIT EL G P +KY PMKV+ + + P + S + F CL K PA RPSA LL F+K+
Sbjct: 18 YSIQSCIGRGNFGDVYKA-VDRVTQEIVAIKVVNLE--HSDEDIELLAQEIFFLAELKSPLITNYIATMLEDVSMWIVMEYCGGGSCSDLLKRSY------VNGLPEEKVSFIIHEVTLGLKYLHEQRKIHRDIKAANILLNEEGMVKLGDFGVSGHIRST----------LKRDTFVGTPYWMAPEVVCCEVDGYNEKADIWSLGITTYELLKGLPPLSKYDPMKVMTNLPKRKPPKLQGPFSDAA---------KDFVAGCLVKTPADRPSAYNLLSFEFVKN 274
BLAST of Serine/threonine-protein kinase OSR1 vs. Ensembl Yeast
Match: KIC1 (Protein kinase of the PAK/Ste20 family, required for cell integrity; physically interacts with Cdc31p (centrin), which is a component of the spindle pole body; part of the RAM network that regulates cellular polarity and morphogenesis [Source:SGD;Acc:S000001144]) HSP 1 Score: 172.94 bits (437), Expect = 4.578e-46 Identity = 103/325 (31.69%), Postives = 178/325 (54.77%), Query Frame = 2
Query: 167 YKINRSIGQGATSNVYEAECLPLNNRLCAMKIINLEKCNSSSLLEEIKREIKSMKNMKN-ENIVTYYASFVNGIELFIIMDVCQRGSLLDIIKRTQSKRDITYGVFDESTIATILKDVLRGLTYIHENGLVHRDLKCGNLLVKDDGIIQIADFGVAAFLAAQPMHTTGASLDNKRFTFVGTPCWMAPEVMQQVKGHNQKADIWSLGITAIELAAGQAPYAKYAPMKVLMLTLQNESPDIDTAASSCNQYSNYGQKYRKFSKACLNKDPAMRPSAKELLQSPFIKSKAKDRDSLIKVLLSEDTLPFERQRSD---ENLCPEKTPTK 1129
+K IG+G VY+ + R+ A+K++NL+ + S +E+++REI+ + ++K NI YY S++ L+IIM+ C GSL +++ G DE I I++++L L IH++ ++HRD+K N+L+ ++G +++ DFGVAA + + +R T GTP WMAPEV+ + ++ K DIWSLGIT E+A G PY ++ + L ++++ P ++ + Y ++F CL++DP R SA +LL+S FI++ S++K L+S L ++ ++ E PE P+K
Sbjct: 23 FKRTEVIGRGKFGVVYKGYNV-KTGRVYAIKVLNLD--SDSDEVEDVQREIQFLASLKQISNITRYYGSYLKDTSLWIIMEHCAGGSLRSLLRP---------GKIDEKYIGVIMRELLVALKCIHKDNVIHRDIKAANVLITNEGNVKLCDFGVAAQVNQTSL---------RRQTMAGTPYWMAPEVIMEGVYYDTKVDIWSLGITTYEIATGNPPYCDVEALRAMQLIIKSKPPRLEDRS--------YSTSLKEFIALCLDEDPKERLSADDLLKSKFIRAHKATPTSILKELISRYLLFRDKNKNKYKIEGSIPENEPSK 318
BLAST of Serine/threonine-protein kinase OSR1 vs. Ensembl Yeast
Match: STE20 (Cdc42p-activated signal transducing kinase; involved in pheromone response, pseudohyphal/invasive growth, vacuole inheritance, down-regulation of sterol uptake; GBB motif binds Ste4p; member of the PAK (p21-activated kinase) family [Source:SGD;Acc:S000000999]) HSP 1 Score: 161.77 bits (408), Expect = 1.992e-42 Identity = 103/290 (35.52%), Postives = 151/290 (52.07%), Query Frame = 2
Query: 185 IGQGATSNVYEAECLPLNNRLCAMKIINLEKCNSSSLLEEIKREIKSMKNMKNENIVTYYASFVNGIELFIIMDVCQRGSLLDIIKRTQSKRDITYGVFDESTIATILKDVLRGLTYIHENGLVHRDLKCGNLLVKDDGIIQIADFGVAAFLAAQPMHTTGASLDNKRFTFVGTPCWMAPEVMQQVKGHNQKADIWSLGITAIELAAGQAPYAKYAPMKVLMLTLQNESPDIDTAASSCNQYSNYGQKYRKFSKACLNKDPAMRPSAKELLQSPFIKSKAKDRDSLIKVL 1054
IGQGA+ VY A + N + A+K +NLEK L I EI MK K+ NIV + S+V +L++IM+ + GSL D++ T+ + E I + ++ L GL ++H G++HRD+K N+L+ +G I++ DFG A + L+ KR T VGTP WMAPEV+ + K + K DIWSLGI IE+ G+ PY P++ L L N +P + + N +KF CL +P R SA ELL +I A+ SL ++
Sbjct: 626 IGQGASGGVYTAYEIGTNVSV-AIKQMNLEKQPKKEL---IINEILVMKGSKHPNIVNFIDSYVLKGDLWVIMEYMEGGSLTDVV---------THCILTEGQIGAVCRETLSGLEFLHSKGVLHRDIKSDNILLSMEGDIKLTDFGFCAQI---------NELNLKRTTMVGTPYWMAPEVVSR-KEYGPKVDIWSLGIMIIEMIEGEPPYLNETPLRALYLIATNGTPKL-------KEPENLSSSLKKFLDWCLCVEPEDRASATELLHDEYITEIAEANSSLAPLV 885
BLAST of Serine/threonine-protein kinase OSR1 vs. Ensembl Yeast
Match: SKM1 (Member of the PAK family of serine/threonine protein kinases; similar to Ste20p; involved in down-regulation of sterol uptake; proposed to be a downstream effector of Cdc42p during polarized growth; SKM1 has a paralog, CLA4, that arose from the whole genome duplication [Source:SGD;Acc:S000005473]) HSP 1 Score: 146.747 bits (369), Expect = 9.390e-38 Identity = 100/328 (30.49%), Postives = 160/328 (48.78%), Query Frame = 2
Query: 86 LGLGTISDSNAVDGSNQTIVWS-NKREDYKINRSIGQGATSNVY----------------EAECLPLNNRLCAMKIINLEKCNSSSLLEEIKREIKSMKNMKNENIVTYYASFV-NGIELFIIMDVCQRGSLLDIIKRT-QSKRDITYGVFDESTIATILKDVLRGLTYIHENGLVHRDLKCGNLLVKDDGIIQIADFGVAAFLAAQPMHTTGASLDNKRFTFVGTPCWMAPEVMQQVKGHNQKADIWSLGITAIELAAGQAPYAKYAPMKVLMLTLQNESPDIDTAASSCNQYSNYGQKYRKFSKACLNKDPAMRPSAKELLQSPFI 1012
L L DSN + +T+ N R +++ GQGA+ VY ++ C + A+K I L + L I E+ M + + ENIV + +++ + EL++IM+ + G L DI+ +S +E+ +A I+K+ +GL ++H ++HRD+K N+L+ G+++I DFG L + +KR T VGTP WMAPE++ Q KG+++K D+WSLGI IE+ G+ PY P+K L L N SP + S Q ++F ACL + R S ++LL F+
Sbjct: 332 LELKNNDDSNEIIMKMKTVAIDVNPRPYFQLVEKAGQGASGAVYLSKRIKLPQENDPRFLKSHCHRVVGERVAIKQIRLSEQPKKQL---IMNELLVMNDSRQENIVNFLEAYIIDDEELWVIMEYMEGGCLTDILDAVARSNTGEHSSPLNENQMAYIVKETCQGLKFLHNKKIIHRDIKSDNILLNSQGLVKITDFGFCVELTEK---------RSKRATMVGTPYWMAPEIVNQ-KGYDEKVDVWSLGIMLIEMIEGEPPYLNEDPLKALYLIANNGSPKLRHPESVSKQ-------TKQFLDACLQVNVESRASVRKLLTFEFL 639
BLAST of Serine/threonine-protein kinase OSR1 vs. Ensembl Yeast
Match: CLA4 (Cdc42p-activated signal transducing kinase; member of the PAK (p21-activated kinase) family, along with Ste20p and Skm1p; involved in septin ring assembly, vacuole inheritance, cytokinesis, sterol uptake regulation; phosphorylates Cdc3p and Cdc10p; CLA4 has a paralog, SKM1, that arose from the whole genome duplication [Source:SGD;Acc:S000005242]) HSP 1 Score: 142.895 bits (359), Expect = 3.127e-36 Identity = 103/338 (30.47%), Postives = 173/338 (51.18%), Query Frame = 2
Query: 98 TISDSNAVDGSNQTIVWSNKREDYKINRSIGQGATSNVYEAE--CLP--------LNNRL--------CAMKIINLEKCNSSSLLEEIKREIKSMKNMKNENIVTYYASFV-NGIELFIIMDVCQRGSLLDIIKRTQSKRDITYGVFDESTIATILKDVLRGLTYIHENGLVHRDLKCGNLLVKDDGIIQIADFGVAAFLAAQPMHTTGASLDNKRFTFVGTPCWMAPEVMQQVKGHNQKADIWSLGITAIELAAGQAPYAKYAPMKVLMLTLQNESPDIDTAASSCNQYSNYGQKYRKFSKACLNKDPAMRPSAKELLQSPF--IKSKAKDRDSLIK 1048
T+S + + + V ++ + +K+ GQGA+ +VY AE +P +NN + A+K + L K L I EI MK+ +++NIV + +++ +L+++M+ + GSL DII+ + + D ++ E IA I+++ +GL ++H+ ++HRD+K N+L+ ++I DFG A L + +KR T VGTP WMAPEV++Q + +++K D+WSLGI IE+ G+ PY P+K L L N +P + S + ++F CL D R S +ELL F + KD SL++
Sbjct: 523 TMSTAEIMSKLKKVTVNADPSQCFKVIEKAGQGASGSVYLAERTHIPTESNMIELINNDIDEPHVGDKVAIKQMVLSKQPRKEL---IVNEILVMKDSRHKNIVNFLEAYLRTDDDLWVVMEFMEGGSLTDIIENSPTN-DNSHSPLTEPQIAYIVRETCQGLKFLHDKHIIHRDIKSDNVLLDTRARVKITDFGFCARLTDK---------RSKRATMVGTPYWMAPEVVKQ-REYDEKIDVWSLGIMTIEMLEGEPPYLNEDPLKALYLIATNGTPKLKHPES-------LSLEIKRFLSVCLCVDVRYRASTEELLHHGFFNMACDPKDLTSLLE 839
BLAST of Serine/threonine-protein kinase OSR1 vs. Ensembl Nematostella
Match: EDO33129 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7ST31]) HSP 1 Score: 337.806 bits (865), Expect = 1.324e-109 Identity = 204/513 (39.77%), Postives = 288/513 (56.14%), Query Frame = 2
Query: 146 WSNKREDYKINRSIGQGATSNVYEAECLPLNNRLCAMKIINLEKCNSSSLLEEIKREIKSMKNMKNENIVTYYASFVNGIELFIIMDVCQRGSLLDIIKR--TQSKRDITYGVFDESTIATILKDVLRGLTYIHENGLVHRDLKCGNLLVKDDGIIQIADFGVAAFLAAQPMHTTGASLDNKRFTFVGTPCWMAPEVM-QQVKGHNQKADIWSLGITAIELAAGQAPYAKYAPMKVLMLTLQNESPDIDTAA-SSCNQYSNYGQKYRKFSKACLNKDPAMRPSAKELLQSPFIKSKAKDRDSLIKVLLSEDTLPFERQRSDENLCPEKTPT------KAFSGEWNFDLQPLGDHLNDIDNKESVDKTENET--------------------------------------FEN-SEPISYRITLRKRNPKKNNELEDISFDYVIGKDSVELLVRELVEADLLDGCDLLLVAHNMSELVANPSVRERV-FALNSPPSTGVANEQELYGYAKVLLR 1534
W N ++DYK+ IG GAT+ V A C N R+ A+K I+LEKC +S ++E+ +EI +M +EN+V YY SFV EL+I+M + GS+LD+IK+ Q + GV +E IAT+L++VL+GL Y H+NGL+HRD+K GN+L+ DG +Q+ADFGV++ ++ T R TFVGTPCWMAPEVM QQV G+N KADIWS GITAIELA G APYAK+ MKVLMLTLQN+ P ++T A S Y Y + ++K CL K+PA RP A ELL++PF K KAK +D LSE +P + + ++ P + GEW + ++D + V + + + F S P +TLR RN KK EL DI FD+ GKD+ E + +ELV A L+DG DL++VA N+ ++V P + + F L S ++ +E+ L G+A++ +
Sbjct: 9 WPNTKDDYKLQEVIGYGATAVVQAAICESKNERV-AIKRIDLEKCGAS--IDEMMKEIHAMSQCNHENVVNYYTSFVVRQELWIVMRLLNGGSMLDVIKQRIKQQPGLVDEGVLEEDIIATVLREVLKGLEYFHKNGLIHRDVKAGNILLATDGSVQLADFGVSSAISDYGDRTK----PKMRKTFVGTPCWMAPEVMEQQVHGYNHKADIWSFGITAIELATGTAPYAKFPAMKVLMLTLQNDPPRMETCADGSTRDYKKYSKVFKKMVSLCLQKEPANRPDANELLKNPFFK-KAKGKD-----YLSEALVPLMPPLGERSQKVKRVPGSSGRLHRTEDGEWEWSDDEGEKDGTEVDTDDEVTQAQESSPPLPDIQVEPSSTQGEYASCYITLVALKQAVLVLWSYLFSGKSAPAQLDLTLRLRNEKK--ELNDIRFDFTFGKDTAEGVAQELVSAGLIDGQDLVIVAANLQKVVDEPQESKFLTFPLKSSGTSETPDEKALIGFAQLTIH 506
BLAST of Serine/threonine-protein kinase OSR1 vs. Ensembl Nematostella
Match: EDO31934 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SWI4]) HSP 1 Score: 189.889 bits (481), Expect = 1.195e-54 Identity = 112/285 (39.30%), Postives = 167/285 (58.60%), Query Frame = 2
Query: 185 IGQGATSNVYEAECLPLNNR---LCAMKIINLEKCNSSSLLEEIKREIKSMKNMKNENIVTYYASFVNGIELFIIMDVCQRGSLLDIIKRTQSKRDITYGVFDESTIATILKDVLRGLTYIHENGLVHRDLKCGNLLVKDDGIIQIADFGVAAFLAAQPMHTTGASLDNKRFTFVGTPCWMAPEVMQQVKGHNQKADIWSLGITAIELAAGQAPYAKYAPMKVLMLTLQNESPDIDTAASSCNQYSNYGQKYRKFSKACLNKDPAMRPSAKELLQSPFIKSKAKD 1030
IG+G+ V++ ++NR + A+KII+LE+ + +EI + + + Y+ S++ G +L+IIM+ GS LD++K G +E IATIL++VL+GL Y+H +HRD+K N+L+ + G +++ADFGVA L NKR TFVGTP WMAPEV++Q ++ KADIWSLGITAIELA G+ P + PM+VL L +N P++ N+ + +++F CLNKDP RP+AKELL+ FIK+ K+
Sbjct: 17 IGKGSFGEVFKG----IDNRTNEVVAIKIIDLEEAEDEIEDIQ--QEITVLSQCDSLYVTKYHGSYLKGTKLWIIMEYLGGGSALDLMKA---------GNIEEFYIATILREVLKGLDYLHTEKKLHRDIKAANVLMSETGDVKLADFGVAGQL---------TDTLNKRNTFVGTPFWMAPEVIKQ-SAYDSKADIWSLGITAIELAKGEPPNSDLHPMRVLFLIPKNNPPELT---------GNFSKAFKEFVSLCLNKDPNDRPTAKELLKHRFIKTAKKN 267
BLAST of Serine/threonine-protein kinase OSR1 vs. Ensembl Nematostella
Match: EDO33667 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SRJ0]) HSP 1 Score: 172.555 bits (436), Expect = 3.244e-47 Identity = 104/303 (34.32%), Postives = 161/303 (53.14%), Query Frame = 2
Query: 152 NKREDYKINRSIGQGATSNVYEAECLPLNNRLCAMKIINLEKCNSSSLLEEIKREIKSMKNMKNENIVTYYASFVNGIELFIIMDVCQRGSLLDIIKRTQSKRDITYGVFDESTIATILKDVLRGLTYIHENGLVHRDLKCGNLLVKDDGIIQIADFGVAAFLAAQPMHTTGASLDNKRFTFVGTPCWMAPEVMQQVKGHNQKADIWSLGITAIELAAGQAPYAKYAPMKVLMLTLQNESPDIDTAASSCNQYSNYGQKYRKFSKACLNKDPAMRPSAKELLQSPFIKSKAKDRDSLIKVLLS 1060
+ ++ Y IGQGA+ VY A + + + A+K +NL + L I EI M+ K+ NIV Y S++ G EL+++M+ GSL D++ T DE IA + ++ L+ L ++H NG++HRD+K N+L+ DG +++ DFG A + + NKR T VGTP WMAPEV+ + K + + D+WSLGI AIE+ G+ PY P++ L L N +P++ ++ F L D R SA+ELLQ PF+K +AK SL+ ++L+
Sbjct: 221 DPKKKYTKFEKIGQGASGTVYTAIEVATGHEV-AIKQMNLSQQPKKEL---IINEILVMRENKHPNIVNYVDSYLVGEELWVVMEYLAGGSLTDVVTET---------CMDEGQIAAVCRECLQALEFLHSNGVIHRDIKSDNILLGMDGQVKLTDFGFCATITPE---------QNKRSTMVGTPYWMAPEVVTR-KQYGPRVDVWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPEL-------AHPEKLSPVFKDFLAQSLEMDVEKRSSARELLQHPFLK-QAKPLASLVPLILA 492
BLAST of Serine/threonine-protein kinase OSR1 vs. Ensembl Nematostella
Match: EDO42845 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S0A9]) HSP 1 Score: 166.392 bits (420), Expect = 1.212e-46 Identity = 97/285 (34.04%), Postives = 156/285 (54.74%), Query Frame = 2
Query: 161 EDYKINRSIGQGATSNVYEAECLPLNNRLCAMKIINLEKCNSSSLLEEIKREIKSMKNMKNENIVTYYASFVNGIELFIIMDVCQRGSLLDIIKRTQSKRDITYGVFDESTIATILKDVLRGLTYIHENGLVHRDLKCGNLLVKDDGIIQIADFGVAAFLAAQPMHTTGASLDNKRFTFVGTPCWMAPEVMQQVKGHNQKADIWSLGITAIELAAGQAPYAKYAPMKVLMLTLQNESPDIDTAASSCNQYSNYGQKYRKFSKACLNKDPAMRPSAKELLQSPFIK 1015
E + + +G+G+ +V++A ++ + +++ +++ + L+EI +EI M+ + +V YY S+ +L+I+M+ C GS+ D++K I E I +LK L+GL Y+H +HRD+K GN+L+ +G ++ADFGVA L T A KR T +GTP WMAPEV+Q+V G++ ADIWSLGITA+E+A G+ PYA PM+ + + P + + ++ F CL K+P R +A ELLQ FI+
Sbjct: 22 EVFDVLEKLGEGSYGSVFKA----MHKE--SGQVVAIKQVPVDTDLQEIIKEISMMQQCDSPYVVKYYGSYFKNTDLWIVMEYCGAGSVSDLMK-------IRNKTLTEEEIKCVLKYTLKGLEYLHLRRKIHRDIKAGNILLNSEGHAKLADFGVAGQLT-----DTMA----KRNTVIGTPFWMAPEVIQEV-GYDCLADIWSLGITAMEMAEGKPPYADIHPMRAIFMIPTKPPPTFRDPG-------QWSEDFKDFVSKCLVKNPEERATATELLQHSFIQ 276
BLAST of Serine/threonine-protein kinase OSR1 vs. Ensembl Nematostella
Match: EDO49047 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RHW1]) HSP 1 Score: 153.68 bits (387), Expect = 4.055e-42 Identity = 97/324 (29.94%), Postives = 170/324 (52.47%), Query Frame = 2
Query: 149 SNKREDYKINRSIGQGATSNVYEAECLPLNNRLCAMKIINLEKCNSSSLLEEIKREIKSMKNMKNENIVTYYASFVNGIELFIIMDVCQRGSLLDIIKRTQSKRDITYGVFDESTIATILKDVLRGLTYIHENGLVHRDLKCGNLLVKDDGIIQIADFGVAAFLAAQPMHTTGASLDNKRFTFVGTPCWMAPEV--MQQVKGHNQKADIWSLGITAIELAAGQAPYAKYAPMKVLMLTLQNESPDIDTAASSCNQYSNYGQKYRKFSKACLNKDPAMRPSAKELLQSPFIKSKAKDRDSLIKVLLSEDTLPFERQRSDENLCPE 1114
N + + + +G G +V++A + + L A+K++ +E + E I++EI M+ ++ NI+ Y +++ +L+I M+ C GS+ D+ T G E+ I+ + + L+GL Y+HE L+HRD+K N+L+ +G +++ADFG++A + KR +F+GTP WMAPE+ +++ G++ K DIW++GITAIE+A Q P PM+ L + + I +++SN + F K L K+P RPSA ++L PF L K +L + + R+ ++NL P+
Sbjct: 12 GNPDKVFDLIEKVGGGTYGDVFKARVIATGD-LAAVKVVKVEPGDD---FELIQQEIAMMQQCRHNNIINYIGAYMRRDKLWIGMEYCGGGSIQDVYCVT--------GPCSETQISFVTVETLKGLAYLHEKSLMHRDIKGANILLTTNGEVKLADFGISARI---------TETMKKRKSFIGTPYWMAPEMAAVERTGGYDLKCDIWAVGITAIEMAELQPPMFDLHPMRALYII--GKKSFIPPTLKEKDKWSN---EMHHFIKVALIKNPKKRPSADKMLTHPFCCR------HLTKAVLQDLLDRYRRKSQEKNLQPD 303
BLAST of Serine/threonine-protein kinase OSR1 vs. Ensembl Medaka
Match: stk39 (serine/threonine kinase 39 [Source:NCBI gene;Acc:101156210]) HSP 1 Score: 346.665 bits (888), Expect = 1.140e-112 Identity = 211/497 (42.45%), Postives = 295/497 (59.36%), Query Frame = 2
Query: 137 TIVWSNKREDYKINRSIGQGATSNVYEAECLPLNNRLCAMKIINLEKCNSSSLLEEIKREIKSMKNMKNENIVTYYASFVNGIELFIIMDVCQRGSLLDIIKRTQSKRDITYGVFDESTIATILKDVLRGLTYIHENGLVHRDLKCGNLLVKDDGIIQIADFGVAAFLAAQPMHTTGASLDNK-RFTFVGTPCWMAPEVMQQVKGHNQKADIWSLGITAIELAAGQAPYAKYAPMKVLMLTLQNESPDIDTAASSCNQYSNYGQKYRKFSKACLNKDPAMRPSAKELLQSPFIKSKAKDRDSLIKVLLSEDTLPFERQRSDENLCPEKTP--TKAFSGEWNFDLQPLGDHLND-----------------IDNKE----------SVDKTENETFENSEPIS--YRITLRKRNPKKNNELEDISFDYVIGKDSVELLVRELVEADLLDGCDLLLVAHNMSELVANPSV-RERVFALNSP-PSTGVANEQELYGYAKV 1525
T W RE Y++ IG GAT+ V A C P R+ A+K INLEKC +S ++E+ +EI++M + NIVTYY SFV EL+++M + GS+LDI+K +SK D +E IATILK+VL GL Y+H NG +HRD+K GN+L+ +DG +QIADFGV+AFLA T G NK R TFVGTPCWMAPEVM+QV+G++ KADIWS GITAIELA G APY +Y PMKVLMLTLQN+ P ++T YG+ +RK CL K+PA RP+A ELL+ FI+ KAK+++ L++ LLS +R R + P + K G+W + L + + DN+E SV + E +EN+ + + LR RN KK EL DI F++ G+D+ + + +EL A L++G D+++VA N+ ++V NP+ R F L S T + +E +L G+A++
Sbjct: 19 TTSWPITREAYELQEVIGSGATAVVQAALCTPRQERV-AIKRINLEKCQTS--MDELLKEIQAMSQCHHPNIVTYYTSFVVKDELWLVMTLLSGGSMLDILKH-RSKEDEKNRALEEPIIATILKEVLEGLDYLHRNGQIHRDVKAGNILLGEDGSVQIADFGVSAFLA-----TGGDMTRNKVRKTFVGTPCWMAPEVMEQVRGYDFKADIWSFGITAIELATGSAPYHRYPPMKVLMLTLQNDPPSLETGVEDKEMLKKYGKSFRKLISMCLQKEPAKRPTAAELLKCKFIQ-KAKNKEYLVEKLLSGAPKISQRARKVRRV-PGSSGHLHKTEDGDWEWSDDELDEGSEEGKAAVNQGRSRRVKYEAKDNEEDANSVPIEGLSVQHPQVEPYENAAFLKGVVNMVLRLRNSKK--ELNDIRFEFTPGRDTADGVSQELYSAGLVNGLDVVIVAANLQKIVDNPTTYRVLTFKLASGCDDTEIPDEVKLIGFAQL 502
BLAST of Serine/threonine-protein kinase OSR1 vs. Ensembl Medaka
Match: oxsr1b (serine/threonine-protein kinase OSR1 [Source:NCBI gene;Acc:101156367]) HSP 1 Score: 320.857 bits (821), Expect = 1.618e-102 Identity = 167/324 (51.54%), Postives = 222/324 (68.52%), Query Frame = 2
Query: 122 DGSNQTIVWSNKREDYKINRSIGQGATSNVYEAECLPLNNRLCAMKIINLEKCNSSSLLEEIKREIKSMKNMKNENIVTYYASFVNGIELFIIMDVCQRGSLLDIIKRTQSKRDITYGVFDESTIATILKDVLRGLTYIHENGLVHRDLKCGNLLVKDDGIIQIADFGVAAFLAAQPMHTTGASLDNK-RFTFVGTPCWMAPEVMQQVKGHNQKADIWSLGITAIELAAGQAPYAKYAPMKVLMLTLQNESPDIDTAASSCNQYSNYGQKYRKFSKACLNKDPAMRPSAKELLQSPFIKSKAKDRDSLIKVLLSEDTLPFERQR 1090
D S+Q WS R+DY+++ IG GAT+ V A C+P ++ A+K INLEKC +S ++E+ +EI++M + NIVTYY SFV EL+++M + GS+LD+IK S+ + GV DE++IAT+LKDVL GL Y+H+NG +HRDLK GN+L+ DDG +QIADFGV+AFLAA G NK R TFVGTPCWMAPEVM+QV+G++ KADIWS GITAIELA G APY KY PMKVLMLTLQN+ P ++T + YG+ +RK +CL KDP RP++ ELL+ F + KAK+ + L LL + ER +
Sbjct: 4 DPSSQP--WSINRDDYELHEVIGSGATAVVQAAYCIPRKEKV-AIKRINLEKCQTS--MDELLKEIQAMSQCHHPNIVTYYTSFVVKDELWLVMKLLSGGSMLDVIKHIISRGEHKSGVLDEASIATVLKDVLDGLEYLHKNGQIHRDLKAGNILLGDDGSVQIADFGVSAFLAA-----GGDMTRNKVRKTFVGTPCWMAPEVMEQVRGYDFKADIWSFGITAIELATGAAPYHKYPPMKVLMLTLQNDPPTLETGITDKEMVKKYGKSFRKMISSCLQKDPEKRPTSLELLKHKFFQ-KAKNHEFLHDRLLQKAPTITERSK 316 HSP 2 Score: 55.4546 bits (132), Expect = 9.981e-8 Identity = 37/95 (38.95%), Postives = 61/95 (64.21%), Query Frame = 2
Query: 1244 PISYRITLRKRNPKKNNELEDISFDYVIGKDSVELLVRELVEADLLDGCDLLLVAHNMSELVANPSVRERV-FALNSPPSTGVANEQELYGYAKV 1525
PIS + LR RN KK EL DI F+++ G+D+ + + +ELV A L+DG D+++VA N+ ++V P + V F L S + V ++ +L G+A++
Sbjct: 425 PIS--LVLRLRNLKK--ELNDIRFEFMPGRDTADGVSQELVSAGLVDGRDVVIVAANLQKIVDEPQSNKSVTFKLAS-GTEEVPDDIKLMGFAQL 514
BLAST of Serine/threonine-protein kinase OSR1 vs. Ensembl Medaka
Match: oxsr1b (serine/threonine-protein kinase OSR1 [Source:NCBI gene;Acc:101156367]) HSP 1 Score: 320.087 bits (819), Expect = 3.460e-102 Identity = 167/324 (51.54%), Postives = 222/324 (68.52%), Query Frame = 2
Query: 122 DGSNQTIVWSNKREDYKINRSIGQGATSNVYEAECLPLNNRLCAMKIINLEKCNSSSLLEEIKREIKSMKNMKNENIVTYYASFVNGIELFIIMDVCQRGSLLDIIKRTQSKRDITYGVFDESTIATILKDVLRGLTYIHENGLVHRDLKCGNLLVKDDGIIQIADFGVAAFLAAQPMHTTGASLDNK-RFTFVGTPCWMAPEVMQQVKGHNQKADIWSLGITAIELAAGQAPYAKYAPMKVLMLTLQNESPDIDTAASSCNQYSNYGQKYRKFSKACLNKDPAMRPSAKELLQSPFIKSKAKDRDSLIKVLLSEDTLPFERQR 1090
D S+Q WS R+DY+++ IG GAT+ V A C+P ++ A+K INLEKC +S ++E+ +EI++M + NIVTYY SFV EL+++M + GS+LD+IK S+ + GV DE++IAT+LKDVL GL Y+H+NG +HRDLK GN+L+ DDG +QIADFGV+AFLAA G NK R TFVGTPCWMAPEVM+QV+G++ KADIWS GITAIELA G APY KY PMKVLMLTLQN+ P ++T + YG+ +RK +CL KDP RP++ ELL+ F + KAK+ + L LL + ER +
Sbjct: 4 DPSSQP--WSINRDDYELHEVIGSGATAVVQAAYCIPRKEKV-AIKRINLEKCQTS--MDELLKEIQAMSQCHHPNIVTYYTSFVVKDELWLVMKLLSGGSMLDVIKHIISRGEHKSGVLDEASIATVLKDVLDGLEYLHKNGQIHRDLKAGNILLGDDGSVQIADFGVSAFLAA-----GGDMTRNKVRKTFVGTPCWMAPEVMEQVRGYDFKADIWSFGITAIELATGAAPYHKYPPMKVLMLTLQNDPPTLETGITDKEMVKKYGKSFRKMISSCLQKDPEKRPTSLELLKHKFFQ-KAKNHEFLHDRLLQKAPTITERSK 316 HSP 2 Score: 52.7582 bits (125), Expect = 8.101e-7 Identity = 30/71 (42.25%), Postives = 47/71 (66.20%), Query Frame = 2
Query: 1244 PISYRITLRKRNPKKNNELEDISFDYVIGKDSVELLVRELVEADLLDGCDLLLVAHNMSELVANPSVRERV 1456
PIS + LR RN KK EL DI F+++ G+D+ + + +ELV A L+DG D+++VA N+ ++V P + V
Sbjct: 425 PIS--LVLRLRNLKK--ELNDIRFEFMPGRDTADGVSQELVSAGLVDGRDVVIVAANLQKIVDEPQSNKSV 491
BLAST of Serine/threonine-protein kinase OSR1 vs. Ensembl Medaka
Match: oxsr1a (serine/threonine-protein kinase OSR1 [Source:NCBI gene;Acc:101161509]) HSP 1 Score: 314.694 bits (805), Expect = 5.191e-100 Identity = 161/307 (52.44%), Postives = 214/307 (69.71%), Query Frame = 2
Query: 146 WSNKREDYKINRSIGQGATSNVYEAECLPLNNRLCAMKIINLEKCNSSSLLEEIKREIKSMKNMKNENIVTYYASFVNGIELFIIMDVCQRGSLLDIIKRTQSKRDITYGVFDESTIATILKDVLRGLTYIHENGLVHRDLKCGNLLVKDDGIIQIADFGVAAFLAAQPMHTTGASLDNK-RFTFVGTPCWMAPEVMQQVKGHNQKADIWSLGITAIELAAGQAPYAKYAPMKVLMLTLQNESPDIDTAASSCNQYSNYGQKYRKFSKACLNKDPAMRPSAKELLQSPFIKSKAKDRDSLIKVLLSE 1063
WS ++DY++ IG GAT+ V A C P ++ A+K INLEKC +S ++E+ +EI++M + NIV+YY SFV EL+++M + GS+LDIIK S+ + GV DE++IATILK+VL GL Y+H+NG +HRDLK GN+L+ +DG +QIADFGV+AFLA T G NK R TFVGTPCWMAPEVM+QV+G++ KADIWS GITAIELA G APY KY PMKVLMLTLQN+ P ++T + YG+ +RK CL KDP RP+A ELL+ F +KAK+ + L ++LL +
Sbjct: 10 WSIDKDDYELKEVIGSGATAVVQAAYCKPRKEKV-AIKRINLEKCQTS--MDELLKEIQAMSQCHHPNIVSYYTSFVVKDELWLVMKLLSGGSVLDIIKHIISRGEHKNGVLDEASIATILKEVLEGLEYLHKNGQIHRDLKAGNILLGEDGSVQIADFGVSAFLA-----TGGDMTRNKVRKTFVGTPCWMAPEVMEQVRGYDFKADIWSFGITAIELATGAAPYHKYPPMKVLMLTLQNDPPCLETGITDKEMVKKYGKSFRKMLALCLQKDPEKRPTAAELLKHKFF-TKAKNNEYLHEILLQK 307 HSP 2 Score: 60.8474 bits (146), Expect = 2.163e-9 Identity = 40/102 (39.22%), Postives = 64/102 (62.75%), Query Frame = 2
Query: 1226 TFENSEPISYRITLRKRNPKKNNELEDISFDYVIGKDSVELLVRELVEADLLDGCDLLLVAHNMSELVANP-SVRERVFALNSP-PSTGVANEQELYGYAKV 1525
F + PIS + LR RN KK EL DI F+++ G+DS + + +ELV A L+DG DL++VA N+ ++V +P S R F L S + + ++ +L G+A++
Sbjct: 423 AFSSGVPIS--LVLRLRNSKK--ELNDIRFEFMPGRDSADGVSQELVSAGLVDGRDLVIVAANLQKIVDDPQSNRSVTFKLASGVEESEIPDDIKLIGFAQL 520
BLAST of Serine/threonine-protein kinase OSR1 vs. Ensembl Medaka
Match: stk39 (serine/threonine kinase 39 [Source:NCBI gene;Acc:101156210]) HSP 1 Score: 311.612 bits (797), Expect = 1.278e-98 Identity = 162/309 (52.43%), Postives = 211/309 (68.28%), Query Frame = 2
Query: 137 TIVWSNKREDYKINRSIGQGATSNVYEAECLPLNNRLCAMKIINLEKCNSSSLLEEIKREIKSMKNMKNENIVTYYASFVNGIELFIIMDVCQRGSLLDIIKRTQSKRDITYGVFDESTIATILKDVLRGLTYIHENGLVHRDLKCGNLLVKDDGIIQIADFGVAAFLAAQPMHTTGASLDNK-RFTFVGTPCWMAPEVMQQVKGHNQKADIWSLGITAIELAAGQAPYAKYAPMKVLMLTLQNESPDIDTAASSCNQYSNYGQKYRKFSKACLNKDPAMRPSAKELLQSPFIKSKAKDRDSLIKVLLS 1060
T W RE Y++ IG GAT+ V A C P R+ A+K INLEKC +S ++E+ +EI++M + NIVTYY SFV EL+++M + GS+LDI+K +SK D +E IATILK+VL GL Y+H NG +HRD+K GN+L+ +DG +QIADFGV+AFLA T G NK R TFVGTPCWMAPEVM+QV+G++ KADIWS GITAIELA G APY +Y PMKVLMLTLQN+ P ++T YG+ +RK CL K+PA RP+A ELL+ FI+ KAK+++ L++ LLS
Sbjct: 19 TTSWPITREAYELQEVIGSGATAVVQAALCTPRQERV-AIKRINLEKCQTS--MDELLKEIQAMSQCHHPNIVTYYTSFVVKDELWLVMTLLSGGSMLDILKH-RSKEDEKNRALEEPIIATILKEVLEGLDYLHRNGQIHRDVKAGNILLGEDGSVQIADFGVSAFLA-----TGGDMTRNKVRKTFVGTPCWMAPEVMEQVRGYDFKADIWSFGITAIELATGSAPYHRYPPMKVLMLTLQNDPPSLETGVEDKEMLKKYGKSFRKLISMCLQKEPAKRPTAAELLKCKFIQ-KAKNKEYLVEKLLS 317 HSP 2 Score: 56.225 bits (134), Expect = 6.694e-8 Identity = 41/117 (35.04%), Postives = 68/117 (58.12%), Query Frame = 2
Query: 1187 IDNKESVDKTENETFENSEPIS--YRITLRKRNPKKNNELEDISFDYVIGKDSVELLVRELVEADLLDGCDLLLVAHNMSELVANPSV-RERVFALNSP-PSTGVANEQELYGYAKV 1525
+D K V T E +EN+ + + LR RN KK EL DI F++ G+D+ + + +EL A L++G D+++VA N+ ++V NP+ R F L S T + +E +L G+A++
Sbjct: 428 VDPKRGV-TTIVEPYENAAFLKGVVNMVLRLRNSKK--ELNDIRFEFTPGRDTADGVSQELYSAGLVNGLDVVIVAANLQKIVDNPTTYRVLTFKLASGCDDTEIPDEVKLIGFAQL 541
BLAST of Serine/threonine-protein kinase OSR1 vs. Planmine SMEST
Match: SMESG000052774.1 (SMESG000052774.1) HSP 1 Score: 1069.3 bits (2764), Expect = 0.000e+0 Identity = 514/514 (100.00%), Postives = 514/514 (100.00%), Query Frame = 2
Query: 47 MSRKFSITRKFSTLGLGTISDSNAVDGSNQTIVWSNKREDYKINRSIGQGATSNVYEAECLPLNNRLCAMKIINLEKCNSSSLLEEIKREIKSMKNMKNENIVTYYASFVNGIELFIIMDVCQRGSLLDIIKRTQSKRDITYGVFDESTIATILKDVLRGLTYIHENGLVHRDLKCGNLLVKDDGIIQIADFGVAAFLAAQPMHTTGASLDNKRFTFVGTPCWMAPEVMQQVKGHNQKADIWSLGITAIELAAGQAPYAKYAPMKVLMLTLQNESPDIDTAASSCNQYSNYGQKYRKFSKACLNKDPAMRPSAKELLQSPFIKSKAKDRDSLIKVLLSEDTLPFERQRSDENLCPEKTPTKAFSGEWNFDLQPLGDHLNDIDNKESVDKTENETFENSEPISYRITLRKRNPKKNNELEDISFDYVIGKDSVELLVRELVEADLLDGCDLLLVAHNMSELVANPSVRERVFALNSPPSTGVANEQELYGYAKVLLRFFGEPKPSEHITANSKYT 1588
MSRKFSITRKFSTLGLGTISDSNAVDGSNQTIVWSNKREDYKINRSIGQGATSNVYEAECLPLNNRLCAMKIINLEKCNSSSLLEEIKREIKSMKNMKNENIVTYYASFVNGIELFIIMDVCQRGSLLDIIKRTQSKRDITYGVFDESTIATILKDVLRGLTYIHENGLVHRDLKCGNLLVKDDGIIQIADFGVAAFLAAQPMHTTGASLDNKRFTFVGTPCWMAPEVMQQVKGHNQKADIWSLGITAIELAAGQAPYAKYAPMKVLMLTLQNESPDIDTAASSCNQYSNYGQKYRKFSKACLNKDPAMRPSAKELLQSPFIKSKAKDRDSLIKVLLSEDTLPFERQRSDENLCPEKTPTKAFSGEWNFDLQPLGDHLNDIDNKESVDKTENETFENSEPISYRITLRKRNPKKNNELEDISFDYVIGKDSVELLVRELVEADLLDGCDLLLVAHNMSELVANPSVRERVFALNSPPSTGVANEQELYGYAKVLLRFFGEPKPSEHITANSKYT
Sbjct: 1 MSRKFSITRKFSTLGLGTISDSNAVDGSNQTIVWSNKREDYKINRSIGQGATSNVYEAECLPLNNRLCAMKIINLEKCNSSSLLEEIKREIKSMKNMKNENIVTYYASFVNGIELFIIMDVCQRGSLLDIIKRTQSKRDITYGVFDESTIATILKDVLRGLTYIHENGLVHRDLKCGNLLVKDDGIIQIADFGVAAFLAAQPMHTTGASLDNKRFTFVGTPCWMAPEVMQQVKGHNQKADIWSLGITAIELAAGQAPYAKYAPMKVLMLTLQNESPDIDTAASSCNQYSNYGQKYRKFSKACLNKDPAMRPSAKELLQSPFIKSKAKDRDSLIKVLLSEDTLPFERQRSDENLCPEKTPTKAFSGEWNFDLQPLGDHLNDIDNKESVDKTENETFENSEPISYRITLRKRNPKKNNELEDISFDYVIGKDSVELLVRELVEADLLDGCDLLLVAHNMSELVANPSVRERVFALNSPPSTGVANEQELYGYAKVLLRFFGEPKPSEHITANSKYT 514
BLAST of Serine/threonine-protein kinase OSR1 vs. Planmine SMEST
Match: SMESG000066296.1 (SMESG000066296.1) HSP 1 Score: 667.537 bits (1721), Expect = 0.000e+0 Identity = 344/484 (71.07%), Postives = 400/484 (82.64%), Query Frame = 2
Query: 107 DSNAVDGSNQTIVWSNKREDYKINRSIGQGATSNVYEAECLPLNNRLCAMKIINLEKCNSSSLLEEIKREIKSMKNMKNENIVTYYASFVNGIELFIIMDVCQRGSLLDIIKRTQSKRDITYGVFDESTIATILKDVLRGLTYIHENGLVHRDLKCGNLLVKDDGIIQIADFGVAAFLAAQPMHTTGASLDNKRFTFVGTPCWMAPEVMQQVKGHNQKADIWSLGITAIELAAGQAPYAKYAPMKVLMLTLQNESPDIDTAASSCNQYSNYGQKYRKFSKACLNKDPAMRPSAKELLQSPFIKSKAKDRDSLIKVLLSEDTLPF-ERQRSDENLCPEKTPTKAFSGEWNFDLQPLGDHLNDIDNKESVDKTENETFENSEPISYRITLRKRNPKKNNELEDISFDYVIGKDSVELLVRELVEADLLDGCDLLLVAHNMSELVANPSVRERVFALNSPPSTGVANEQELYGYAKVLLRFFGEPKP 1555
D A D S+ + W N + DY I SIGQGATS VYEA C LNNR CAMKIINLEKC+SS+LL+EIK+EI+ M+N+KNENIVTYYAS V G EL I+MD+CQRGSLLDIIK TQ+KRDI+ GV DE+TIATI+KDVL+GL+YIHENGLVHRDLKCGNLLVKDD +IQIADFGVA FLAA+PM TG SLD+KRFTFVGTPCWMAPEVMQQVKG+NQKADIWS+GIT IE+A GQAPYAKY PMKVLMLTLQN+ PDIDTAA+S NQY+NYG KYRKF+K CL KDP+ RPSAKELLQSPFIKSK++DR+ L K+LL+ D P ER+ DE EK P K FSGEWNFD++ D + + + V K++ EN + YRITLRKRNPK+NNEL+DISF+YV+GKDSV++L RELVEADLLDGCDLLLVAHN+SELVA P++RERVFALNSPP++GV +E +L GYAKVLLRF E P
Sbjct: 3 DGTAPDASHPIVQWPNNKSDYIIKGSIGQGATSTVYEASCPILNNRKCAMKIINLEKCSSSTLLDEIKKEIRGMRNLKNENIVTYYASLVAGTELCILMDLCQRGSLLDIIKATQNKRDISSGVLDENTIATIMKDVLKGLSYIHENGLVHRDLKCGNLLVKDDAVIQIADFGVAGFLAARPMEATGMSLDDKRFTFVGTPCWMAPEVMQQVKGYNQKADIWSIGITVIEMATGQAPYAKYTPMKVLMLTLQNDPPDIDTAAASSNQYTNYGHKYRKFTKVCLCKDPSQRPSAKELLQSPFIKSKSRDRELLSKMLLNCDIPPAPERKVRDEK--QEKNP-KDFSGEWNFDIK-GKDDDSSSGDDQPVQKSKISVTEN---VFYRITLRKRNPKQNNELQDISFNYVLGKDSVDVLARELVEADLLDGCDLLLVAHNLSELVAEPTMRERVFALNSPPASGVISEADLNGYAKVLLRFAHEDLP 479
BLAST of Serine/threonine-protein kinase OSR1 vs. Planmine SMEST
Match: SMESG000010489.1 (SMESG000010489.1) HSP 1 Score: 192.2 bits (487), Expect = 6.938e-54 Identity = 110/287 (38.33%), Postives = 168/287 (58.54%), Query Frame = 2
Query: 167 YKINRSIGQGATSNVYEAECLPLNNRLCAMKIINLEKCNSSSLLEEIKREIKSMKNMKNENIVTYYASFVNGIELFIIMDVCQRGSLLDIIKRTQSKRDITYGVFDESTIATILKDVLRGLTYIHENGLVHRDLKCGNLLVKDDGIIQIADFGVAAFLAAQPMHTTGASLDNKRFTFVGTPCWMAPEVMQQVKGHNQKADIWSLGITAIELAAGQAPYAKYAPMKVLMLTLQNESPDIDTAASSCNQYSNYGQKYRKFSKACLNKDPAMRPSAKELLQSPFIKSKAK 1027
Y + IG+G+ V++ ++ + A+KII+LE+ + +EI + + + Y+ S++ +L+IIM+ GS +D++K G +E+ IA IL+++L+GL Y+H +HRD+K N+L+ ++G +++ADFGVA L +TT NKR TFVGTP WMAPEV++Q ++ KADIWSLGITAIELA G+ P++ PM+VL L +N SP +D ++ + +R F CLNK+P RPSA+ELL FIK K
Sbjct: 18 YDVLERIGKGSFGEVHKG-VNKIDKTIVAIKIIDLEEAEDEIEDIQ--QEINVLSQCDSPYVTKYFGSYLKVTKLWIIMEYLGGGSAMDLMKP---------GPLNETYIAIILREILKGLDYLHSQKKLHRDIKAANVLLSENGDVKLADFGVAGQLT----NTT-----NKRVTFVGTPFWMAPEVIKQ-SAYDFKADIWSLGITAIELAKGEPPHSNLHPMRVLFLIPKNPSPQLD---------GSFSKLFRDFVDCCLNKEPDNRPSARELLHHGFIKKAKK 273
BLAST of Serine/threonine-protein kinase OSR1 vs. Planmine SMEST
Match: SMESG000018196.1 (SMESG000018196.1) HSP 1 Score: 181.03 bits (458), Expect = 2.905e-50 Identity = 115/315 (36.51%), Postives = 175/315 (55.56%), Query Frame = 2
Query: 161 EDYKINRSIGQGATSNVYEAECLPLNNRLCAMKIINLEKCNSSSLLEEIKREIKSMKNMKNENIVTYYASFVNGIELFIIMDVCQRGSLLDIIKRTQSKRDITYGVFDESTIATILKDVLRGLTYIHENGLVHRDLKCGNLLVKDDGIIQIADFGVAAFLAAQPMHTTGASLDNKRFTFVGTPCWMAPEVMQQVKGHNQKADIWSLGITAIELAAGQAPYAKYAPMKVLMLTLQNESPDIDTAASSCNQYSNYGQKYRKFSKACLNKDPAMRPSAKELLQSPFIKSKAKDRDSLIKVLLSEDTLPFERQRSDENL 1105
E ++I +G+G+ +VY+A+ N A K++ ++ S L +I +EI M+ K++ IV YY SF + +L+I+M+ C GS+ DI+ R ++K +E IA IL+ L+GL YIH+ +HRD+K GN+L+ +DG ++ADFGVA L+ T A KR T +GTP WMAPEV+Q++ G++ ADIWSLGITAIE+A G+ PYA PM+ L + P + S + + F CL K+P RPSA +LL + A D LI + + + RQ ++ +
Sbjct: 15 EVFQIESKLGKGSYGSVYKAKHKK-NGFTVAAKLVPVD-----SELSDIVKEISIMQQCKSDYIVQYYGSFYDSHDLWIVMEYCGAGSVSDIM-RLRNK------TCNEEEIAIILQGSLKGLEYIHQLKKIHRDIKAGNILLTEDGNAKLADFGVAGQLS-----DTLA----KRNTVIGTPYWMAPEVIQEI-GYHYSADIWSLGITAIEMADGKPPYADIHPMRALFMIPSQPPPTLLNP-------SIWSPSFVNFITQCLVKNPDQRPSASQLLLNCEFIINASSPDHLIATIKQANEIRENRQHEEDTI 299
BLAST of Serine/threonine-protein kinase OSR1 vs. Planmine SMEST
Match: SMESG000029685.1 (SMESG000029685.1) HSP 1 Score: 183.726 bits (465), Expect = 6.115e-49 Identity = 109/297 (36.70%), Postives = 171/297 (57.58%), Query Frame = 2
Query: 140 IVWSNKREDYKINRSIGQGATSNVYEAECLPLNNRLCAMKIINLEKCNSSSLLEEIKREIKSMKNMKNENIVTYYASFVNGIELFIIMDVCQRGSLLDIIKRTQSKRDITYGVFDESTIATILKDVLRGLTYIHENGLVHRDLKCGNLLVKDDGIIQIADFGVAAFLAAQPMHTTGASLDNKRFTFVGTPCWMAPEV--MQQVKGHNQKADIWSLGITAIELAAGQAPYAKYAPMKVL-MLTLQNESPDIDTAASSCNQYSNYGQKYRKFSKACLNKDPAMRPSAKELLQSPFIKSK 1021
I+ + +EDYK+ ++IG G VY+A NN + A+KI+ K + ++ I +EI ++++ ++NIV Y+ S++ +L+I M+ C S+ DI T +R + +E+ IA + +D L GL Y+H+ G +HRD+K N+L+ +DG ++IADFGVAA + KR +F+GTP WMAPEV +++ G+++K DIW++GITAIE A Q P PMK L +L+++N A + + QK+ F K CLNK+ RP A LLQ F+ K
Sbjct: 16 IIKKDPKEDYKLIKNIGSGTYGEVYKA-IHRRNNTVSAVKIV---KVDIKDDIKAIAQEIHTLRDCNHKNIVKYFGSYLRKNKLWICMEFCGGFSIQDIY--TNIRRPL-----EENCIAYVTRDTLDGLAYMHKQGKIHRDIKGANILLTEDGQVKIADFGVAAQI---------TQTIQKRCSFIGTPYWMAPEVAAVERKGGYDEKCDIWAVGITAIEYAELQPPMFDLHPMKALHLLSMRN------YKAPVLQNKTKWSQKFHSFLKICLNKNEKRRPDAMTLLQHDFVTQK 286 The following BLAST results are available for this feature:
BLAST of Serine/threonine-protein kinase OSR1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Serine/threonine-protein kinase OSR1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Serine/threonine-protein kinase OSR1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Serine/threonine-protein kinase OSR1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Serine/threonine-protein kinase OSR1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Serine/threonine-protein kinase OSR1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Serine/threonine-protein kinase OSR1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Serine/threonine-protein kinase OSR1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Serine/threonine-protein kinase OSR1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Serine/threonine-protein kinase OSR1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Serine/threonine-protein kinase OSR1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 5
BLAST of Serine/threonine-protein kinase OSR1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Serine/threonine-protein kinase OSR1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Serine/threonine-protein kinase OSR1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30017401 ID=SMED30017401|Name=Serine/threonine-protein kinase OSR1|organism=Schmidtea mediterranea sexual|type=transcript|length=1790bpback to top protein sequence of SMED30017401-orf-1 >SMED30017401-orf-1 ID=SMED30017401-orf-1|Name=SMED30017401-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=515bp MSRKFSITRKFSTLGLGTISDSNAVDGSNQTIVWSNKREDYKINRSIGQGback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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