von Willebrand factor A domain containing 3B
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30017387 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 9
Homology
BLAST of von Willebrand factor A domain containing 3B vs. Ensembl Human
Match: VWA3B (von Willebrand factor A domain containing 3B [Source:HGNC Symbol;Acc:HGNC:28385]) HSP 1 Score: 538.495 bits (1386), Expect = 1.238e-162 Identity = 355/1110 (31.98%), Postives = 564/1110 (50.81%), Query Frame = 3
Query: 210 VSSEQWLNKFGLKASNLDSSSLYPRLGFARLEGFNDVLKKPIHSRYGDNLFPKHFR-EDGLTFNVVAKKEKLLQVQQELENAVQLYQQRLEWLSSESRRLFGVIEEHCVTXXXXXXXXXXRDFDQFICAIERFLNEQIRCIAKFNLIRVQENKCQLSNNLLPVSKDNLANGIDWLWQIDRTSATNSANLVEALIRASNNKENEALYLITEDLSSDGSREVLREKVKQLKIPLNIISYNCKDPEFISYLKCLVLMTGGRFHSYLFNLEVDAYESSPLDSENPKANLLL--KKKVYGGSIGGIGTRNDCVAVFSEIEEAKALINQIKSLINQIPEKKGIYDNHYHHKHPLRVWNHAYGQKEWESCCSYKKPHPCRYCVDDNSQSKLAVHIPR--EEYMSSQEWLAKYGLKSRKLDFFDVLSGVCFRHCDGVVDVLEPPPVDKLDFMEQQNATLHQKLINAKYCDKFAHVKWKDGSLVHVQMSSDVHRLYSERMKLCLLAITRRIEWLRQGSRELFGTIMEDQVYILIDISASMEPHISFVKDKLYTLIQEQLRHKSKINFVAFNTKALPWRDRLVDVTEANLKSAWQWLEGLTCQGSTNTLSALQFAIKDRNCQGIYLLTDGRPDQPTKTVLSQIRLQYRLPIHTISFNCADLEANTFLCELARETGGRFHYFNEISGGADCTNENELEAWESEDIKLLKSEYRLGFDSLEKVTKLRDECHKLAWKSEVVRKKEQKSTRKTMA----PGCNQNPYFSQISPSRPKCENREIKYPRPIKAKNTFRKQQKEQENDPIWSGTIKLLNLDSTTVASQSDAY---QSFLEALSSRDEN---EQEWVIDETQEIIDRQ-TERYKKILEDEYNEAMSXXXXXXXXXXXXXXXXXXXQWLHIYGLVPQHMTILDALAPTIVKVRPKYVPIIDKYVMSKVFEEILPISHVVTEGSPKRGYKPVVRLVNPLAVDLKAYQEKLENLMNKYRKKLRKLIQIHIGDSTLNAFDEMLVKYPLGNDDVKRWVMKAFRDANWPMGEEELEMFMNEIYIGQKYFIQAGDLLRIRGKTGPGKG-GKDETPEFEPFDGELQNTNEPFSKVLLAAMKGATILAPGPEDGYYY 3488
+SSE+WL GLK++ L + ++GF E + L +P+ SRY D LFP+ +R EDG +N+ AK E + Q + L AV+ Y+QR++WL+S+SR++FGVI E CVTI++D + + D A+ L EQ+ I +FN+IRV + + N PV++ ++A I W+ ++ + A ++AL+ A +K E++Y + S+E+L ++ ++ P+ +S+N + I++LK L T RFH++ E + P S N++ +K+ G G G R D V+ E+EEA + + QI+ L+ + P P VD S++ +V I E+ S+ WL KYGLK++KL +DVL+ FRH DGVVD+ P + + Q +A ++K ++AKYC +F H WKDGSLVHV ++ + + YSER+ L I RRI+WL+ GS+ LFG + D +YILID S SM+ + VKDK+ IQEQL++KSK NFV F+ +A+ WR++L +V E NL+ A W+ + STNTLSAL+ A D+ Q IYLLTDGRPDQP +TV+ Q++ +PI+TISFN D AN FL E+A TGG FH++N C + EA ++ED+ LL E G LEK+ L E + W + + K ++ + P P S + ++ N +K P + + +K+ E+ ++ +L S+ + + D S ALS ++ + +EW+ D++ E + R+ ++ Y D +E WL YGLV + +T++DAL+ V YVP++DK+V+SKVF+E+ P++HV + + + L+NP L Y+ K+E + Y K+L K++ + D P+ + K + +A NWP+ +EL M +EI G+ Y QA +L K K G+ + + P +P +KG ++A E+G+Y+
Sbjct: 34 ISSEKWLQLHGLKSNKLTLKQILSQIGFPHCEDYVASLGRPVASRYADGLFPQLYRAEDGRVYNLTAKSELIYQFVEHLTQAVESYKQRMDWLTSKSRQIFGVILEQCVTIVLDFGGILEGELDLCREALTMVLQEQVAHITEFNIIRVSQEPVKWQENATPVTEQSIATAISWVEKLTVELTVSEAGRLDALLEAGRDKTIESIYYFVVGDVPEESKELLLQRALEIPCPVYTVSFNARGEGTIAFLKDLSAKTHSRFHAFAERTECVEF---PAFSTKDGDNVMTWNSRKLKGKLPPGAGVREDVFLVWQEMEEACSTLAQIQRLVAE-------------------------------------PPKPDVATVDCESETT-SVEIASNPEDTWDSKTWLQKYGLKAQKLSLYDVLADCSFRHADGVVDIKAKPENESV----QTSAETNKKTVHAKYCSRFVHAPWKDGSLVHVNITKEKCKWYSERIHTALARIRRRIKWLQDGSQSLFGRLHNDCIYILIDTSHSMKSKLDLVKDKIIQFIQEQLKYKSKFNFVKFDGQAVAWREQLAEVNEDNLEQAQSWIRDIKIGSSTNTLSALKTAFADKETQAIYLLTDGRPDQPPETVIDQVKRFQEIPIYTISFNYNDEIANRFLKEVAALTGGEFHFYN-----FGCKDPTPPEAVQNEDLTLLVKEMEQGHSDLEKMQDLYSESLIMDWWYNAEKDGDSKHQKEICSMISTPEKCAKPQ-SDVDSTQTSSLNM-LKGPWGLSDQKVQKKKVLHAESTKTSLLRSQMSSLRSSACSERKDGLSNASSRRTALSDKEMSILLAEEWLDDKSSEKVTREGSQVYDHDSSDVSSE----------------------NWLKTYGLVAKKLTLMDALSVAAVPHSSTYVPVLDKHVVSKVFDEVFPLAHVCNDTNK-------MTLINPQGAKLNIYKRKVEQAIQSYEKRLNKIVWRALSQEEKEKLD---ANKPIQYLENKTVLNQALERLNWPISLKELSMLESEILAGKMYIQQAMELQEAAKKNYANKAPGEQQKLQGNPTKKTKSKRPDP--------LKGQKVIARCDENGFYF 1051 HSP 2 Score: 131.339 bits (329), Expect = 1.076e-29 Identity = 82/298 (27.52%), Postives = 149/298 (50.00%), Query Frame = 3
Query: 1335 NSQSKLAVHIPREEYMSSQEWLAKYGLKSRKLDFFDVLSGVCFRHCDGVVDVLEPPPVDKLDFMEQQNATLHQKLINAKYCDK-FAHV-KWKDGSLVHVQMSSDVHRLYSERMKLCLLAITRRIEWLRQGSRELFGTIMEDQVYILIDISASMEPHISFVKDKLYTLIQEQLRHKSKINFVAFNTKALPWRDRLVDVTEANLKSAWQWLEGLTCQ---GSTNTLSALQFAIKDRNCQGIYLLTDGRPDQPTKTVLSQIRLQYRLPIHTISFNCADLEANTFLCELARETGGRFHYFNE 2213
N+++ LA + +SS++WL +GLKS KL +LS + F HC+ V L P + ++Y D F + + +DG + ++ S++ + E + + + +R++WL SR++FG I+E V I++D +E + ++ L ++QEQ+ H ++ N + + + + W++ VTE ++ +A W+E LT + L AL A +D+ + IY G + +K +L Q L+ P++T+SFN FL +L+ +T RFH F E
Sbjct: 23 NTKTDLA----EQSLISSEKWLQLHGLKSNKLTLKQILSQIGFPHCEDYVASLGRP-------------------VASRYADGLFPQLYRAEDGRVYNLTAKSELIYQFVEHLTQAVESYKQRMDWLTSKSRQIFGVILEQCVTIVLDFGGILEGELDLCREALTMVLQEQVAHITEFNIIRVSQEPVKWQENATPVTEQSIATAISWVEKLTVELTVSEAGRLDALLEAGRDKTIESIYYFVVGDVPEESKELLLQRALEIPCPVYTVSFNARGEGTIAFLKDLSAKTHSRFHAFAE 297
BLAST of von Willebrand factor A domain containing 3B vs. Ensembl Human
Match: VWA3B (von Willebrand factor A domain containing 3B [Source:HGNC Symbol;Acc:HGNC:28385]) HSP 1 Score: 397.512 bits (1020), Expect = 1.793e-120 Identity = 230/630 (36.51%), Postives = 350/630 (55.56%), Query Frame = 3
Query: 210 VSSEQWLNKFGLKASNLDSSSLYPRLGFARLEGFNDVLKKPIHSRYGDNLFPKHFR-EDGLTFNVVAKKEKLLQVQQELENAVQLYQQRLEWLSSESRRLFGVIEEHCVTXXXXXXXXXXRDFDQFICAIERFLNEQIRCIAKFNLIRVQENKCQLSNNLLPVSKDNLANGIDWLWQIDRTSATNSANLVEALIRASNNKENEALYLITEDLSSDGSREVLREKVKQLKIPLNIISYNCKDPEFISYLKCLVLMTGGRFHSYLFNLEVDAYESSPLDSENPKANLLL--KKKVYGGSIGGIGTRNDCVAVFSEIEEAKALINQIKSLINQIPEKKGIYDNHYHHKHPLRVWNHAYGQKEWESCCSYKKPHPCRYCVDDNSQSKLAVHIPR--EEYMSSQEWLAKYGLKSRKLDFFDVLSGVCFRHCDGVVDVLEPPPVDKLDFMEQQNATLHQKLINAKYCDKFAHVKWKDGSLVHVQMSSDVHRLYSERMKLCLLAITRRIEWLRQGSRELFGTIMEDQVYILIDISASMEPHISFVKDKLYTLIQEQLRHKSKINFVAFNTKALPWRDRLVDVTEANLKSAWQWLEGLTCQGSTNTLSALQFAIKDRNCQGIYLLTDGRPDQPTKTVL 2084
+SSE+WL GLK++ L + ++GF E + L +P+ SRY D LFP+ +R EDG +N+ AK E + Q + L AV+ Y+QR++WL+S+SR++FGVI E CVTI++D + + D A+ L EQ+ I +FN+IRV + + N PV++ ++A I W+ ++ + A ++AL+ A +K E++Y + S+E+L ++ ++ P+ +S+N + I++LK L T RFH++ E + P S N++ +K+ G G G R D V+ E+EEA + + QI+ L+ + P P VD S++ +V I E+ S+ WL KYGLK++KL +DVL+ FRH DGVVD+ P + + Q +A ++K ++AKYC +F H WKDGSLVHV ++ + + YSER+ L I RRI+WL+ GS+ LFG + D +YILID S SM+ + VKDK+ IQEQL++KSK NFV F+ +A+ WR++L +V E NL+ A W+ + STNTLSAL+ A D+ Q IYLLTDGRPDQ T + L
Sbjct: 34 ISSEKWLQLHGLKSNKLTLKQILSQIGFPHCEDYVASLGRPVASRYADGLFPQLYRAEDGRVYNLTAKSELIYQFVEHLTQAVESYKQRMDWLTSKSRQIFGVILEQCVTIVLDFGGILEGELDLCREALTMVLQEQVAHITEFNIIRVSQEPVKWQENATPVTEQSIATAISWVEKLTVELTVSEAGRLDALLEAGRDKTIESIYYFVVGDVPEESKELLLQRALEIPCPVYTVSFNARGEGTIAFLKDLSAKTHSRFHAFAERTECVEF---PAFSTKDGDNVMTWNSRKLKGKLPPGAGVREDVFLVWQEMEEACSTLAQIQRLVAE-------------------------------------PPKPDVATVDCESETT-SVEIASNPEDTWDSKTWLQKYGLKAQKLSLYDVLADCSFRHADGVVDIKAKPENESV----QTSAETNKKTVHAKYCSRFVHAPWKDGSLVHVNITKEKCKWYSERIHTALARIRRRIKWLQDGSQSLFGRLHNDCIYILIDTSHSMKSKLDLVKDKIIQFIQEQLKYKSKFNFVKFDGQAVAWREQLAEVNEDNLEQAQSWIRDIKIGSSTNTLSALKTAFADKETQAIYLLTDGRPDQGTSSHL 618 HSP 2 Score: 130.183 bits (326), Expect = 4.925e-30 Identity = 82/298 (27.52%), Postives = 149/298 (50.00%), Query Frame = 3
Query: 1335 NSQSKLAVHIPREEYMSSQEWLAKYGLKSRKLDFFDVLSGVCFRHCDGVVDVLEPPPVDKLDFMEQQNATLHQKLINAKYCDK-FAHV-KWKDGSLVHVQMSSDVHRLYSERMKLCLLAITRRIEWLRQGSRELFGTIMEDQVYILIDISASMEPHISFVKDKLYTLIQEQLRHKSKINFVAFNTKALPWRDRLVDVTEANLKSAWQWLEGLTCQ---GSTNTLSALQFAIKDRNCQGIYLLTDGRPDQPTKTVLSQIRLQYRLPIHTISFNCADLEANTFLCELARETGGRFHYFNE 2213
N+++ LA + +SS++WL +GLKS KL +LS + F HC+ V L P + ++Y D F + + +DG + ++ S++ + E + + + +R++WL SR++FG I+E V I++D +E + ++ L ++QEQ+ H ++ N + + + + W++ VTE ++ +A W+E LT + L AL A +D+ + IY G + +K +L Q L+ P++T+SFN FL +L+ +T RFH F E
Sbjct: 23 NTKTDLA----EQSLISSEKWLQLHGLKSNKLTLKQILSQIGFPHCEDYVASLGRP-------------------VASRYADGLFPQLYRAEDGRVYNLTAKSELIYQFVEHLTQAVESYKQRMDWLTSKSRQIFGVILEQCVTIVLDFGGILEGELDLCREALTMVLQEQVAHITEFNIIRVSQEPVKWQENATPVTEQSIATAISWVEKLTVELTVSEAGRLDALLEAGRDKTIESIYYFVVGDVPEESKELLLQRALEIPCPVYTVSFNARGEGTIAFLKDLSAKTHSRFHAFAE 297
BLAST of von Willebrand factor A domain containing 3B vs. Ensembl Human
Match: VWA3B (von Willebrand factor A domain containing 3B [Source:HGNC Symbol;Acc:HGNC:28385]) HSP 1 Score: 185.267 bits (469), Expect = 9.884e-50 Identity = 108/333 (32.43%), Postives = 184/333 (55.26%), Query Frame = 3
Query: 210 VSSEQWLNKFGLKASNLDSSSLYPRLGFARLEGFNDVLKKPIHSRYGDNLFPKHFR-EDGLTFNVVAKKEKLLQVQQELENAVQLYQQRLEWLSSESRRLFGVIEEHCVTXXXXXXXXXXRDFDQFICAIERFLNEQIRCIAKFNLIRVQENKCQLSNNLLPVSKDNLANGIDWLWQIDRTSATNSANLVEALIRASNNKENEALYLITEDLSSDGSREVLREKVKQLKIPLNIISYNCKDPEFISYLKCLVLMTGGRFHSYLFNLEVDAYESSPLDSENPKANLLL--KKKVYGGSIGGIGTRNDCVAVFSEIEEAKALINQIKSLINQIPE 1199
+SSE+WL GLK++ L + ++GF E + L +P+ SRY D LFP+ +R EDG +N+ AK E + Q + L AV+ Y+QR++WL+S+SR++FGVI E CVTI++D + + D A+ L EQ+ I +FN+IRV + + N PV++ ++A I W+ ++ + A ++AL+ A +K E++Y + S+E+L ++ ++ P+ +S+N + I++LK L T RFH++ E + P S N++ +K+ G G G R D V+ E+EEA + + QI+ L+ + P+
Sbjct: 34 ISSEKWLQLHGLKSNKLTLKQILSQIGFPHCEDYVASLGRPVASRYADGLFPQLYRAEDGRVYNLTAKSELIYQFVEHLTQAVESYKQRMDWLTSKSRQIFGVILEQCVTIVLDFGGILEGELDLCREALTMVLQEQVAHITEFNIIRVSQEPVKWQENATPVTEQSIATAISWVEKLTVELTVSEAGRLDALLEAGRDKTIESIYYFVVGDVPEESKELLLQRALEIPCPVYTVSFNARGEGTIAFLKDLSAKTHSRFHAFAERTECVEF---PAFSTKDGDNVMTWNSRKLKGKLPPGAGVREDVFLVWQEMEEACSTLAQIQRLVAEPPK 363 HSP 2 Score: 129.798 bits (325), Expect = 6.073e-31 Identity = 82/298 (27.52%), Postives = 149/298 (50.00%), Query Frame = 3
Query: 1335 NSQSKLAVHIPREEYMSSQEWLAKYGLKSRKLDFFDVLSGVCFRHCDGVVDVLEPPPVDKLDFMEQQNATLHQKLINAKYCDK-FAHV-KWKDGSLVHVQMSSDVHRLYSERMKLCLLAITRRIEWLRQGSRELFGTIMEDQVYILIDISASMEPHISFVKDKLYTLIQEQLRHKSKINFVAFNTKALPWRDRLVDVTEANLKSAWQWLEGLTCQ---GSTNTLSALQFAIKDRNCQGIYLLTDGRPDQPTKTVLSQIRLQYRLPIHTISFNCADLEANTFLCELARETGGRFHYFNE 2213
N+++ LA + +SS++WL +GLKS KL +LS + F HC+ V L P + ++Y D F + + +DG + ++ S++ + E + + + +R++WL SR++FG I+E V I++D +E + ++ L ++QEQ+ H ++ N + + + + W++ VTE ++ +A W+E LT + L AL A +D+ + IY G + +K +L Q L+ P++T+SFN FL +L+ +T RFH F E
Sbjct: 23 NTKTDLA----EQSLISSEKWLQLHGLKSNKLTLKQILSQIGFPHCEDYVASLGRP-------------------VASRYADGLFPQLYRAEDGRVYNLTAKSELIYQFVEHLTQAVESYKQRMDWLTSKSRQIFGVILEQCVTIVLDFGGILEGELDLCREALTMVLQEQVAHITEFNIIRVSQEPVKWQENATPVTEQSIATAISWVEKLTVELTVSEAGRLDALLEAGRDKTIESIYYFVVGDVPEESKELLLQRALEIPCPVYTVSFNARGEGTIAFLKDLSAKTHSRFHAFAE 297
BLAST of von Willebrand factor A domain containing 3B vs. Ensembl Human
Match: VWA3B (von Willebrand factor A domain containing 3B [Source:HGNC Symbol;Acc:HGNC:28385]) HSP 1 Score: 176.407 bits (446), Expect = 1.697e-44 Identity = 141/506 (27.87%), Postives = 232/506 (45.85%), Query Frame = 3
Query: 2007 AIKDRNCQGIYLLTDGRPDQPTKTVLSQIRLQYRLPIHTISFNCADLEANTFLCELARETGGRFHYFNEISGGADCTNENELEAWESEDIKLLKSEYRLGFDSLEKVTKLRDECHKLAWKSEVVRKKEQKSTRKTMA----PGCNQNPYFSQISPSRPKCENREIKYPRPIKAKNTFRKQQKEQENDPIWSGTIKLLNLDSTTVASQSDAY---QSFLEALSSRDEN---EQEWVIDETQEIIDRQ-TERYKKILEDEYNEAMSXXXXXXXXXXXXXXXXXXXQWLHIYGLVPQHMTILDALAPTIVKVRPKYVPIIDKYVMSKVFEEILPISHVVTEGSPKRGYKPVVRLVNPLAVDLKAYQEKLENLMNKYRKKLRKLIQIHIGDSTLNAFDEMLVKYPLGNDDVKRWVMKAFRDANWPMGEEELEMFMNEIYIGQKYFIQAGDLLRIRGKTGPGKG-GKDETPEFEPFDGELQNTNEPFSKVLLAAMKGATILAPGPEDGYYY 3488
A D+ Q IYLLTDGRPDQP +TV+ Q++ +PI+TISFN D AN FL E+A TGG FH++N C + EA ++ED+ LL E G LEK+ L E + W + + K ++ + P P S + ++ N +K P + + +K+ E+ ++ +L S+ + + D S ALS ++ + +EW+ D++ E + R+ ++ Y D +E WL YGLV + +T++DAL+ V YVP++DK+V+SKVF+E+ P++HV + + + L+NP L Y+ K+E + Y K+L K++ + D P+ + K + +A NWP+ +EL M +EI G+ Y QA +L K K G+ + + P +P +KG ++A E+G+Y+
Sbjct: 4 AFADKETQAIYLLTDGRPDQPPETVIDQVKRFQEIPIYTISFNYNDEIANRFLKEVAALTGGEFHFYN-----FGCKDPTPPEAVQNEDLTLLVKEMEQGHSDLEKMQDLYSESLIMDWWYNAEKDGDSKHQKEICSMISTPEKCAKPQ-SDVDSTQTSSLNM-LKGPWGLSDQKVQKKKVLHAESTKTSLLRSQMSSLRSSACSERKDGLSNASSRRTALSDKEMSILLAEEWLDDKSSEKVTREGSQVYDHDSSDVSSE----------------------NWLKTYGLVAKKLTLMDALSVAAVPHSSTYVPVLDKHVVSKVFDEVFPLAHVCNDTNK-------MTLINPQGAKLNIYKRKVEQAIQSYEKRLNKIVWRALSQEEKEKLD---ANKPIQYLENKTVLNQALERLNWPISLKELSMLESEILAGKMYIQQAMELQEAAKKNYANKAPGEQQKLQGNPTKKTKSKRPDP--------LKGQKVIARCDENGFYF 462
BLAST of von Willebrand factor A domain containing 3B vs. Ensembl Human
Match: VWA3A (von Willebrand factor A domain containing 3A [Source:HGNC Symbol;Acc:HGNC:27088]) HSP 1 Score: 173.326 bits (438), Expect = 1.441e-42 Identity = 118/363 (32.51%), Postives = 181/363 (49.86%), Query Frame = 3
Query: 1353 AVHIPREEYM-SSQEWLAKYGLKSRKLDFFDVLSGVCFRHCDGVVDVLEPPPVDKLDFMEQQNATLHQKLINAKYCDKFAHVKWKDGSLVHVQMSSDVHRLYSERMKLCLLAITRRIEWLRQGSRELFGTIMEDQVYILIDISASMEPHISFVKDKLYTLIQEQLRH-KSKINFVAFNTKALPWRDRLVDVTEANLKSAWQWLEGLTCQGSTNTLSALQFAIKDRNCQGIYLLTDGRPDQPTKTVLSQI---RLQYRLPIHTISFNCADLEANTFLCELARETGGRFH----------YFNEISGGADCTNENELEAWESEDIKLLKSEYRLGFDSLEKVTKLRDECHKLAWKSEVVRKKEQK 2396
++ +PR++ + SSQEW+AKYGLK KL+ + C G Q+ +AK+C F V+ G + H+Q + +Y ++ L +R++WL GSR LFGT++E +V IL+D S SM P++ VK +L LI EQLR N ++F W+D LV+ T+A A QW+ L QGST+ L AL A + +G+YLLTDG+PD VL+++ R + + +HTIS NC+D A FL +LA TGGR+H + ++ G + L +E +D+++L E +TK R W+++ R + QK
Sbjct: 850 SIDLPRKDTVCSSQEWVAKYGLKKLKLEISRCMGPNCTHQKSG------------------------QRSASAKHCSIFPSVEIH-GVVRHIQWTPREMEVYIRHLEKVLRRYVQRLQWLLSGSRRLFGTVLESKVCILLDTSGSMGPYLQQVKTELVLLIWEQLRKCCDSFNLLSFAESFQSWQDTLVETTDAACHEAMQWVTHLQAQGSTSILQALLKAFSFHDLEGLYLLTDGKPDTSCSLVLNEVQKLREKRDVKVHTISLNCSDRAAVEFLRKLASFTGGRYHCPVGEDTLSKIHSLLTKGFINEKDPTLPPFEGDDLRILAQE----------ITKARS----FLWQAQSFRSQLQK 1173 HSP 2 Score: 168.703 bits (426), Expect = 3.717e-41 Identity = 194/811 (23.92%), Postives = 344/811 (42.42%), Query Frame = 3
Query: 216 SEQWLNKFGLKASNLDSSSLYPRLGFARLEGFNDVLKKPIHSRYGDNLFPKHFREDGLTFNVVAKKEKLLQVQQELENAVQLYQQRLEWLSSESRRLFGVIEEHCVTXXXXXXXXXXR-DFDQFICAIERFLNEQIRCIAKFNLIRVQENKCQLSNNLLPVSKDNLANGIDWLWQIDRTSATNSANLVEALIRASNNKENEALYLITEDLSSDGSREVLREKVKQLKIP----LNIISYNCKDPEFISYLKCLVLMTGGRFHSYLFNLEVDAYESSPLD---SENPKANLLLKKKVYGGSIGGIGTRNDCVAVFSEIEEAKALINQIKSLINQIPEKKGIYDNHYHHKHPLRVWNHAYGQKEWESCCSYKKPHPCRYCVDDNSQSKLAVHIPREEYMSSQEWLAKYGLKSRKLDFFDVLSGVCFRHCDGVVDVLEPPPVDKLDFMEQQNATLHQKLINAKYCDKFAHVKWKDGSLVHVQMSSDVHRLYSERMKLCLLAITRRIEWLRQGSRELFGTIMEDQVYILIDISASMEPHISFVKDKLYTLIQEQLRHKSKINFVAFNTKALPWRDRLVDVTEANLKSAWQWLEGLTCQGSTNTLSALQFAI----KDRN---CQGIYLLTDGRPDQPTKTV---LSQIRLQYRLPIHTISFNCADLEANT--------------FLCELARETGGRFHYFNEISGGADCTNENELEAWESEDIKLLKSEYRLGFDSLEK----VTKLRDECHKLAWKSEVVRKKEQ----KSTRKTMAPGCNQNPYFSQIS----PSRPKCENREIKYPRPIKAK 2516
SE WL+ LK L + L + G LE +V++K S +HF + +L + +++YQ+R++WL+ S++ FG+I+ V+I+ID+ + ++F + ++EQ+ K ++ N L + + VS L W + +NL++AL + K ++L I D E+L + ++Q + ++ I+Y C D + LK L G +H Y + +++ Y S +D +E KA LL + + + C A+ +EE I LI+ +P+ H PL + P + S+ EWL GLK++KL + VL+ F + V +L+ + ++T+H+K + +W DG++ ++ + Y +++ + RRIEWL SR ++GT+ E +V +L+DISA+ +I ++ L L++EQL +K N +AF + WR +V V+ NL+SAW+W L C+GS N LSAL+ A+ KD++ QGIYL T G PDQ T+ +++ L ++ F + + +T E+ R GGRFH+F + +ES+DI + SE + +K + L++ K+ S + ++K + +S K + P P +++S P R K + RP+ ++
Sbjct: 90 SEDWLSAHSLKCQKLTLADLISQ-GTEVLEEGTNVVQKICFS----TQIIRHF-------------------ESKLSDTIEVYQERIQWLTENSKKAFGLIKGARVSILIDVSAISSGPQKEEFQKDLMSLIDEQLSHKEKLFVLSFGTNAGSLWPDPMEVSASTLQELKLW---VKTLQPDGGSNLLQALKKIFTLKGLDSLVAIMRS-CPDQPSEILSDYIQQSTMGRDLIIHFITYRCDDQMPPAVLKNLAEAVRGYYHCY--SPKMEHYTSRDMDELLAEIQKAQSLLSH------VQALQHSSPCEALTCTMEEISTEITN-GPLISLLPKPP-------KHDAPL------------------------------------TIEFPNLDKTSA-EWLKVNGLKAKKLSLYQVLAPNAFSPVEEFVPILQ----------KTVSSTIHEKAM--------IQFEWHDGTVKNIHVDPPFLYKYQQQLSRAMRMYERRIEWLSLASRRIWGTVCEKRVVVLLDISATNSMYIIHIQHSLRLLLEEQLSNKDCFNLIAFGSTIESWRPEMVPVSHNNLQSAWRWALNLRCRGSRNVLSALRKAVEVDFKDKDKHQSQGIYLFTGGIPDQDMPTLSAYMAEACGGCDLQLNVCLFYVGEPKMDTTPPARYASHTDTAAAYKEVTRAAGGRFHWFGDTG------------IYESDDINSIMSEMEKALNYSQKCAFLMASLKNHSGKVLGSSALPKEKPKTLQLRSQPKKLCPPRPTVPLGARMSIKDDPDREKSPPLKSLKWRPLSSR 789 HSP 3 Score: 83.5741 bits (205), Expect = 4.382e-15 Identity = 73/266 (27.44%), Postives = 127/266 (47.74%), Query Frame = 3
Query: 213 SSEQWLNKFGLKASNLDSSSLYPRLGFARLEGFNDVLKKPIH---SRYGDNLFPKHFREDGLTFNVVAKKEKLLQVQQELENAVQLYQQRLEWLSSESRRLFGVIEEHCVTXXXXXXXXXXRDFDQFICAIERFLNEQIR-CIAKFNLIRVQENKCQLSNNLLPVSKDNLANGIDWLWQIDRTSATNSANLVEALIRASNNKENEALYLITEDLSSDGSREVLREKVKQLK----IPLNIISYNCKDPEFISYLKCLVLMTGGRFH 986
SS++W+ K+GLK L+ +R G N +K S ++FP G+ ++ ++ + LE ++ Y QRL+WL S SRRLFG + E V I++D Q + + EQ+R C FNL+ E+ + L+ + + W+ + A S ++++AL++A + + E LYL+T D D S ++ +V++L+ + ++ IS NC D + +L+ L TGGR+H
Sbjct: 861 SSQEWVAKYGLKKLKLE---------ISRCMGPNCTHQKSGQRSASAKHCSIFPS-VEIHGVVRHIQWTPREMEVYIRHLEKVLRRYVQRLQWLLSGSRRLFGTVLESKVCILLDTSGSMGPYLQQVKTELVLLIWEQLRKCCDSFNLLSFAESFQSWQDTLVETTDAACHEAMQWVTHLQ---AQGSTSILQALLKAFSFHDLEGLYLLT-DGKPDTSCSLVLNEVQKLREKRDVKVHTISLNCSDRAAVEFLRKLASFTGGRYH 1112 HSP 4 Score: 74.7146 bits (182), Expect = 2.103e-12 Identity = 74/303 (24.42%), Postives = 130/303 (42.90%), Query Frame = 3
Query: 204 LQVSSEQWLNKFGLKASNLDSSSLYPRLGFARLEGFNDVLKKPIHSRYGDNLFPKHFREDGLTFNVVAKKEKLLQVQQELENAVQLYQQRLEWLSSESRRLFGVIEEHCVTXXXXXXXXXXRDFDQFICAIERFLNEQIRCIAKFNLIRVQENKCQLSNNLLPVSKDNLANGIDWLWQIDRTSATNSANLVEALIRA-------SNNKENEALYLITEDLSSDGSREV---LREKVKQLKIPLNIISYNCKDPEF--------------ISYLKCLVLMTGGRFHSYLFNLEVDAYESSPLDS 1040
L +S +WL GLKA L + F+ +E F +L+K + S + + DG N+ L + QQ+L A+++Y++R+EWLS SRR++G + E V +++DI N ++ L EQ+ FNLI ++PVS +NL + W W ++ S N++ AL +A + +++ +YL T + + + E + LN+ + +P+ + K + GGRFH + + YES ++S
Sbjct: 403 LDKTSAEWLKVNGLKAKKLSLYQVLAPNAFSPVEEFVPILQKTVSSTIHEKAMIQFEWHDGTVKNIHVDPPFLYKYQQQLSRAMRMYERRIEWLSLASRRIWGTVCEKRVVVLLDISATNSMYIIHIQHSLRLLLEEQLSNKDCFNLIAFGSTIESWRPEMVPVSHNNLQSA--WRWALN-LRCRGSRNVLSALRKAVEVDFKDKDKHQSQGIYLFTGGIPDQDMPTLSAYMAEACGGCDLQLNVCLFYVGEPKMDTTPPARYASHTDTAAAYKEVTRAAGGRFHWF---GDTGIYESDDINS 699
BLAST of von Willebrand factor A domain containing 3B vs. Ensembl Zebrafish
Match: vwa3a (von Willebrand factor A domain containing 3A [Source:ZFIN;Acc:ZDB-GENE-131121-527]) HSP 1 Score: 162.925 bits (411), Expect = 1.299e-42 Identity = 108/346 (31.21%), Postives = 181/346 (52.31%), Query Frame = 3
Query: 1293 SYKKPHPCRYCVDDNSQSKLAVHIPREEYM-SSQEWLAKYGLKSRKLDFFDVLSGVCFRHCDGVVDVLEPPPVDKLDFMEQQNATLHQKLINAKYCDKFAHVKWKDGSLVHVQMSSDVHRLYSERMKLCLLAITRRIEWLRQGSRELFGTIMEDQVYILIDISASMEPHISFVKDKLYTLIQEQLRHKS-KINFVAFNTKALPWRDRLVDVTEANLKSAWQWLEGLTCQGSTNTLSALQFAIKDRNCQGIYLLTDGRPDQPTKTVLSQ---IRLQYRLPIHTISFNCADLEANTFLCELARETGGRFHYFNEISGG-------ADCTNENELEAWESEDIKLLKSE 2294
SY KP R +S ++ +P+ E + S+++WL ++G+++ LD +LSG RH D +V P V Q+ ++AKYC F ++ +G++ H+ +S + Y + + +L +R++WL GSR +FG+++E +V +L+D+S SM ++ L LI +QL S + N +AF+ WR LV TE A QWL + GS++TL+ALQ A + G+YL++DGR D +L++ +R + +HTI+ NC+D ++ FL LA + GGRFH E + +D ++ L +E +D+K L E
Sbjct: 57 SYPKPKSVR-------KSIASIKLPKHEGICSTKQWLKRFGIRNLHLDLHRLLSGPECRHQDTLV-----PSV--------------QRRVSAKYCAIFPSIQI-NGAVKHLHLSPAELKQYISQTETLMLRYCQRLQWLLTGSRRMFGSVLEKEVCLLLDVSGSMASCFPELQKGLTLLIWDQLHANSVRFNMLAFSRGLCMWRPALVQSTEDQCVHAVQWLSQINTHGSSSTLTALQTACGLADGVGVYLISDGRSDCSHSLILTEMETLRREKSFTVHTIALNCSDRSSSDFLKRLAHKNGGRFHQAPESTDPDLIREQLSDPSSALNLPEFEGDDLKRLTEE 375 HSP 2 Score: 77.0258 bits (188), Expect = 8.129e-14 Identity = 65/263 (24.71%), Postives = 124/263 (47.15%), Query Frame = 3
Query: 213 SSEQWLNKFGLKASNLDSSSLYPRLGFARLEGFNDVLKKPIHSRYGDNLFPKHFREDGLTFNVVAKKEKLLQVQQELENAVQLYQQRLEWLSSESRRLFGVIEEHCVTXXXXXXXXXXRDFDQFICAIERFLNEQIRC-IAKFNLIRVQENKCQLSNNLLPVSKDNLANGIDWLWQIDRTSATNSANLVEALIRASNNKENEALYLITEDLSSDGSREVLREKVKQLK----IPLNIISYNCKDPEFISYLKCLVLMTGGRFH 986
S++QWL +FG++ +LD L + +++ + ++Y +FP + +G ++ +L Q + E + Y QRL+WL + SRR+FG + E V +++D+ F + + + +Q+ +FN++ C L+ ++D + + WL QI+ S++ + AL A + +YLI+ D SD S ++ +++ L+ ++ I+ NC D +LK L GGRFH
Sbjct: 81 STKQWLKRFGIRNLHLDLHRLLSGPECRHQDTLVPSVQRRVSAKYC-AIFPS-IQINGAVKHLHLSPAELKQYISQTETLMLRYCQRLQWLLTGSRRMFGSVLEKEVCLLLDVSGSMASCFPELQKGLTLLIWDQLHANSVRFNMLAFSRGLCMWRPALVQSTEDQCVHAVQWLSQIN---THGSSSTLTALQTACGLADGVGVYLIS-DGRSDCSHSLILTEMETLRREKSFTVHTIALNCSDRSSSDFLKRLAHKNGGRFH 337
BLAST of von Willebrand factor A domain containing 3B vs. Ensembl Zebrafish
Match: si:dkey-8l13.5 (si:dkey-8l13.5 [Source:ZFIN;Acc:ZDB-GENE-141216-349]) HSP 1 Score: 65.4698 bits (158), Expect = 5.259e-10 Identity = 51/205 (24.88%), Postives = 87/205 (42.44%), Query Frame = 3
Query: 1755 VYILIDISASMEPHISFVKDKLY-TLIQEQLRHKSKINFVAFNTKALPWRDRLVDVTEANLKSAWQWLEGLTCQGSTNTLSALQFAIKDRNCQGIYLLTDGRPDQPTKTVLSQIRLQYRLPIHTISFN---CADLEANTFLCELARETGGRFHYFNEISGGADCTNENELEAWESEDIKLLKSEYRLGFDSLEKVTKLRDECHKL 2357
+ ++D S M + VK+ + TL+ + S N ++F+ KA PW R++ + + A W+ L + +AL A D C ++L+T PD PT+ + S + R P+HT + + + + FL L+ T G + S G E++ LL S DS++K T D H +
Sbjct: 24 ISFVLDCSEGMSGVLGAVKNLIIQTLLTKASLRDSLFNIISFSYKATPWSSRMLPCSPDVVYEALSWIHTLQTSSGRDFHTALALAFSDPACHSVHLVTSSVPDNPTQCLASLSTMVTR-PVHTFYISDKTSINSDTSDFLQCLSSTTRGSCYIMALNSAGG------------VEEVSLLHSTD----DSIQKTTYAEDTLHSM 211
BLAST of von Willebrand factor A domain containing 3B vs. Ensembl Xenopus
Match: ENSXETT00000049307.1 (pep primary_assembly:Xenopus_tropicalis_v9.1:2:109671931:109699265:1 gene:ENSXETG00000020946.1 transcript:ENSXETT00000049307.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 440.269 bits (1131), Expect = 7.408e-133 Identity = 273/790 (34.56%), Postives = 420/790 (53.16%), Query Frame = 3
Query: 195 DAKLQVSSEQWLNKFGLKASNLDSSSLYPRLGFARLEGFNDVLKKPIHSRYGDNLFPKHFREDGLTFNVVAKKEKLLQVQQELENAVQLYQQRLEWLSSESRRLFGVIEEHCVTXXXXXXXXXXRDFDQFICAIERFLNEQIRCIAKFNLIRVQENKCQLSNNLLPVSKDNLANGIDWLWQIDRTSATN---SAN-LVEALIRASNNKENEALYLITEDLSSDGSREVLREKVKQLKIPLNIISYNCKDPEFISYLKCLVLMTGGRFHSYLFNLEVDAYESSPLDSENPKANLLLKKKVYGGSIGGIGT---------RNDCVAVFSEIEEAKALINQIKSLINQIPEKKGIYDNHYHHKHPLRVWNHAYGQKEWESCCSYKKPHPCRYCVDDNSQSKLAVHIPREEYMSSQEWLAKYGLKSRKLDFFDVLSGVCFRHCDGVVDVLEPPPVDKLDFMEQQNATLHQKLINAKYCDKFAHVKWKDGSLVHVQMSSDVHRLYSERMKLCLLAITRRIEWLRQGSRELFGTIMEDQVYILIDISASMEPHISFVKDKLYTLIQEQLRHKSKINFVAFNTKALPWRDRLVDVTEANLKSAWQWLEGLTCQGSTNTLSALQFAIKDRNCQGIYLLTDGRPDQPTKTVLSQIRLQYRLPIHTISFNCADLEANTFLCELARETGGRFHYFNEISGGADCTNENELEAWESEDIKLLKSEYRLGFDSLEKVTKLRDECHKLAWKSEVVRKKEQKSTRKTMAP----GCNQNPYFSQISPSRPKCENREIKYPRPIKA 2513
DA SS +WL GLK L + +LGF + E + L +P+ SRY LFP+ + G +N+ AKKE+ LQ + L N ++LY +RL WL+S SR +FGVI+E+ V +++ +K F+ + A + EQ+ I+ FN+I V + + + + VS+D++ ++W+ N +AN L EAL+ + EA+Y T + S+ +++L + V P++ +SYN + E I++LK + T GR H Y ++ + N LK K ++ T + D + E++EA+ ++ Q++ ++ + +NH L I E+Y+SS++WL KYGLK++KL F+DV + FRH DGVVD+ P + + Q +A KLINAKYCD+F H +WKDGS+VH+ ++ + R Y ERMK L + RRI+WL+QGSRELFGTI+ED+VYILID S SM+ + VK+K++ LI+EQL+HK NFV F++K W+ RL VTE L+ A W++ L STNTL ALQ A D + + IYLLTDGRPDQP +T+L+Q+ Q +PIHTISF+C D++AN+FL +L+ +T GRFH + ++ + + + SEDI LL++E + G L+KV K EC L W ++ KS + P P Q++ S + ++ ++ K+
Sbjct: 6 DAHTLTSSSKWLKTHGLKKKKLSMMKILSQLGFQQKEDYVSKLGRPVSSRYSQGLFPQ-YNFAGKIYNLTAKKEQFLQKVESLTNTIELYNERLGWLTSGSRAIFGVIQENSVIFVLECGCLSKEQFEMYQDAFCLLIREQVAHISNFNIIWVSQVPEKWHDKQVHVSQDSIETAVEWVHNTQHPPVENPECAANALSEALLY-----QVEAVYYFTAEDISEVKKQLLLKYVSDSPCPVHFVSYNPQKEETITFLKEISHQTSGRCHVY--------------KADCKQLNTALKLKEVNAALPTSTTEKTHEELDLQQDEFLMMKELDEAQNILKQLQDILTNFYPSDDVINNH------------------------------------------LMPEIKVEDYVSSKQWLIKYGLKAQKLQFYDVFADCAFRHSDGVVDIKTKPEDESM----QTDADTKMKLINAKYCDQFVHTQWKDGSVVHLYITKEKWRWYEERMKTVLEQMERRIQWLQQGSRELFGTILEDRVYILIDTSHSMKDKLFLVKEKMFQLIEEQLKHKLMFNFVKFDSKVEAWKSRLAKVTEDTLQEASCWVKELQVGSSTNTLRALQVAFNDSSTEAIYLLTDGRPDQPAETILAQVNFQKSVPIHTISFSCNDVDANSFLYQLSCKTEGRFHCYT-----SNLRDPKAPQPFVSEDICLLQNEIKQGKADLQKVQKFYTECLILDWYHNGDKETPYKSNHEKAQPVQEMTTASTPLHRQMNTSLRQLRRKKTRHAEQTKS 724 HSP 2 Score: 109.383 bits (272), Expect = 3.240e-23 Identity = 131/526 (24.90%), Postives = 219/526 (41.63%), Query Frame = 3
Query: 105 KNIVSTIKRTDAVI----VPEIDMKLYPTKVWNPDAKLQVSSEQWLNKFGLKASNLDSSSLYPRLGFARLEGFNDVLKKP---------------IHSRYGDNLFPKHFREDGLTFNVVAKKEKLLQVQQELENAVQLYQQRLEWLSSESRRLFGVIEEHCVTXXXXXXXXXXRDFDQFICAIER---FLNEQIRCIAKFNLIRVQENKCQLSNNLLPVSKDNLANGIDWLWQIDRTSATNSANLVEALIRASNNKENEALYLITEDLSSDGSREVLREKVKQLKIPLNIISYNCKDPEFISYLKCLVLMTGGRFHSYLFNLEVDAYESSPLDSEN----------PKANLLLKKKVY-----------GGSIGGIGTRNDCVAVFSEIEEAKA-LINQIKSLINQIPEKKGIYDNHYHHKHPLRVWNHAYGQKEWESCCSYKKPHPCRY-----------------CVDDNSQSKLAVHIPREEY-MSSQEWLAKYGLKSRKLDFFDVLSGVCFRHCDGVVDVLE 1496
++I++ +D VI +PEI ++ Y VSS+QWL K+GLKA L ++ F +G D+ KP I+++Y D ++ DG ++ KEK ++ ++ ++ ++R++WL SR LFG I E V I+ID + K D+ E+ + EQ++ FN ++ + L V++D L W+ ++ S+TN+ + AL A N+ EA+YL+T+ + +L + Q +P++ IS++C D + S+L L T GRFH Y NL D P SE+ KA+L +K Y G + ++ E+ A L Q+ + + Q+ KK H + ++G K ES P R +D N+ K + P++ MSS WL +GL +R+L D L+ H V +L+
Sbjct: 325 QDILTNFYPSDDVINNHLMPEIKVEDY------------VSSKQWLIKYGLKAQKLQFYDVFADCAFRHSDGVVDIKTKPEDESMQTDADTKMKLINAKYCDQFVHTQWK-DGSVVHLYITKEKWRWYEERMKTVLEQMERRIQWLQQGSRELFGTILEDRVYILIDTSHSMK---DKLFLVKEKMFQLIEEQLKHKLMFNFVKFDSKVEAWKSRLAKVTEDTLQEASCWVKELQVGSSTNT---LRALQVAFNDSSTEAIYLLTDGRPDQPAETILAQVNFQKSVPIHTISFSCNDVDANSFLYQLSCKTEGRFHCYTSNLR-DPKAPQPFVSEDICLLQNEIKQGKADLQKVQKFYTECLILDWYHNGDKETPYKSNHEKAQPVQEMTTASTPLHRQMNTSLRQLRRKKT---RHAEQTKSSLLRAQSHGVKLGESPTEINMPQETREGFLSNSMKPTTDLKECNIIDSNTSLKKSKKSPKDCLDMSSSRWLKIHGLVARRLTIMDSLAPTTVPHTAKYVPILD 827 HSP 3 Score: 62.3882 bits (150), Expect = 8.442e-9 Identity = 26/46 (56.52%), Postives = 37/46 (80.43%), Query Frame = 3
Query: 2823 QWLHIYGLVPQHMTILDALAPTIVKVRPKYVPIIDKYVMSKVFEEI 2960
+WL I+GLV + +TI+D+LAPT V KYVPI+DK++ SKVF+E+
Sbjct: 793 RWLKIHGLVARRLTIMDSLAPTTVPHTAKYVPILDKHIFSKVFDEV 838
BLAST of von Willebrand factor A domain containing 3B vs. Ensembl Xenopus
Match: muc4 (mucin 4, cell surface associated [Source:Xenbase;Acc:XB-GENE-852599]) HSP 1 Score: 159.073 bits (401), Expect = 1.085e-41 Identity = 106/351 (30.20%), Postives = 167/351 (47.58%), Query Frame = 3
Query: 1335 NSQSKLAVHIPREEYMSSQEWLAKYGLKSRKLDFFDVLSGVCFRHCDGVVDVLEPPPVDKLDFMEQQNATLHQKLINAKYCDKFAHVKWKDGSLVHVQMSSDVHRLYSERMKLCLLAITRRIEWLRQGSRELFGTIMEDQVYILIDISASMEPHISFVKDKLYTLIQEQLRHKSKINFVAFNTKALPWRDRLVDVTEANLKSAWQWLEGLTCQGSTNTLSALQFAI-------KDRNCQGIYLLTDGRPDQPTKTV---LSQIRLQYRLPIHTISF-----NCADLEANT-----FLCELARETGGRFHYFNEISGGADCTNENELEAWESEDIKLLKSEYRLGFDSLEKV 2327
N L + IP +S EWL K GLK++KL + +L+ + + V +L+ + ++TLH++ +W DG++ ++ + V R Y ++ +RI+WL GSR L+G + E +V +L+DIS S HI ++ L L++EQ+ +K N +AF ++ W+ +V T NL+ AW+W+ L C+G N L A++ A+ +++ QGIYL T G PDQ TV LS+ L +H F N DL +T L +LA + GRFH+F+E ES+DI L SE + KV
Sbjct: 22 NHDGPLNIEIPNFSPKTSAEWLKKNGLKAKKLSLYQILAPNAYSLVEEFVPILQ----------KTVSSTLHER--------AMMQFEWHDGTVKNIHVDPPVLREYQRQLAKMARTYEKRIDWLTNGSRRLWGAVCEKRVVLLVDISLSNSMHIIHIQHSLRLLLEEQMSNKDLFNIIAFGSEITSWKSEMVPPTAENLQRAWKWVLSLNCEGGRNVLGAMRRAVEVNFIDNENQESQGIYLFTSGVPDQDLHTVSAYLSEATSGSDLQLHVCLFSVGEMNVEDLTEDTNNTTGILKDLAHISNGRFHWFDEKG------------LIESDDISFLISEMEKAMNYSSKV 342 HSP 2 Score: 69.707 bits (169), Expect = 1.448e-11 Identity = 70/301 (23.26%), Postives = 131/301 (43.52%), Query Frame = 3
Query: 213 SSEQWLNKFGLKASNLDSSSLYPRLGFARLEGFNDVLKKPIHSRYGDNLFPKHFREDGLTFNVVAKKEKLLQVQQELENAVQLYQQRLEWLSSESRRLFGVIEEHCVTXXXXXXXXXXRDFDQFICAIERFLNEQIRCIAKFNLIRVQENKCQLSNNLLPVSKDNLANGIDWLWQIDRTSATNSANLVEALIRA-------SNNKENEALYLITEDLSSDGSREV---LREKVKQLKIPLNIISYNCKDPEF----------ISYLKCLVLMTGGRFHSYLFNLEVDAYESSPLDSENPKA 1055
+S +WL K GLKA L + ++ +E F +L+K + S + + DG N+ L + Q++L + Y++R++WL++ SRRL+G + E V +++DI N ++ L EQ+ FN+I + ++P + +NL W+ ++ N++ A+ RA + N+E++ +YL T + V L E + L++ ++ + LK L ++ GRFH + +++ + S L SE KA
Sbjct: 38 TSAEWLKKNGLKAKKLSLYQILAPNAYSLVEEFVPILQKTVSSTLHERAMMQFEWHDGTVKNIHVDPPVLREYQRQLAKMARTYEKRIDWLTNGSRRLWGAVCEKRVVLLVDISLSNSMHIIHIQHSLRLLLEEQMSNKDLFNIIAFGSEITSWKSEMVPPTAENLQRAWKWVLSLN---CEGGRNVLGAMRRAVEVNFIDNENQESQGIYLFTSGVPDQDLHTVSAYLSEATSGSDLQLHVCLFSVGEMNVEDLTEDTNNTTGILKDLAHISNGRFHWFDEKGLIESDDISFLISEMEKA 335
BLAST of von Willebrand factor A domain containing 3B vs. Ensembl Xenopus
Match: muc4 (mucin 4, cell surface associated [Source:Xenbase;Acc:XB-GENE-852599]) HSP 1 Score: 154.451 bits (389), Expect = 8.481e-39 Identity = 109/353 (30.88%), Postives = 170/353 (48.16%), Query Frame = 3
Query: 1335 NSQSKLAVHIPREEYMSSQEWLAKYGLKSRKLDFFDVLSGVCFRHCDGVVDVLEPPPVDKLDFMEQQNATLHQKLINAKYCDKFAHVKWKDGSLVHVQMSSDVHRLYSERMKLCLLAIT--RRIEWLRQGSRELFGTIMEDQVYILIDISASMEPHISFVKDKLYTLIQEQLRHKSKINFVAFNTKALPWRDRLVDVTEANLKSAWQWLEGLTCQGSTNTLSALQFAI-------KDRNCQGIYLLTDGRPDQPTKTV---LSQIRLQYRLPIHTISF-----NCADLEANT-----FLCELARETGGRFHYFNEISGGADCTNENELEAWESEDIKLLKSEYRLGFDSLEKV 2327
N L + IP +S EWL K GLK++KL + +L+ + + V +L+ + ++TLH++ +W DG++ ++ + V R Y +L +A T +RI+WL GSR L+G + E +V +L+DIS S HI ++ L L++EQ+ +K N +AF ++ W+ +V T NL+ AW+W+ L C+G N L A++ A+ +++ QGIYL T G PDQ TV LS+ L +H F N DL +T L +LA + GRFH+F+E ES+DI L SE + KV
Sbjct: 159 NHDGPLNIEIPNFSPKTSAEWLKKNGLKAKKLSLYQILAPNAYSLVEEFVPILQ----------KTVSSTLHER--------AMMQFEWHDGTVKNIHVDPPVLREY----QLAKMARTYEKRIDWLTNGSRRLWGAVCEKRVVLLVDISLSNSMHIIHIQHSLRLLLEEQMSNKDLFNIIAFGSEITSWKSEMVPPTAENLQRAWKWVLSLNCEGGRNVLGAMRRAVEVNFIDNENQESQGIYLFTSGVPDQDLHTVSAYLSEATSGSDLQLHVCLFSVGEMNVEDLTEDTNNTTGILKDLAHISNGRFHWFDEKG------------LIESDDISFLISEMEKAMNYSSKV 477 HSP 2 Score: 63.5438 bits (153), Expect = 2.493e-9 Identity = 70/301 (23.26%), Postives = 129/301 (42.86%), Query Frame = 3
Query: 213 SSEQWLNKFGLKASNLDSSSLYPRLGFARLEGFNDVLKKPIHSRYGDNLFPKHFREDGLTFNVVAKKEKLLQVQQELENAVQLYQQRLEWLSSESRRLFGVIEEHCVTXXXXXXXXXXRDFDQFICAIERFLNEQIRCIAKFNLIRVQENKCQLSNNLLPVSKDNLANGIDWLWQIDRTSATNSANLVEALIRA-------SNNKENEALYLITEDLSSDGSREV---LREKVKQLKIPLNIISYNCKDPEF----------ISYLKCLVLMTGGRFHSYLFNLEVDAYESSPLDSENPKA 1055
+S +WL K GLKA L + ++ +E F +L+K + S + + DG N+ L + Q L + Y++R++WL++ SRRL+G + E V +++DI N ++ L EQ+ FN+I + ++P + +NL W+ ++ N++ A+ RA + N+E++ +YL T + V L E + L++ ++ + LK L ++ GRFH + +++ + S L SE KA
Sbjct: 175 TSAEWLKKNGLKAKKLSLYQILAPNAYSLVEEFVPILQKTVSSTLHERAMMQFEWHDGTVKNIHVDPPVLREYQ--LAKMARTYEKRIDWLTNGSRRLWGAVCEKRVVLLVDISLSNSMHIIHIQHSLRLLLEEQMSNKDLFNIIAFGSEITSWKSEMVPPTAENLQRAWKWVLSLN---CEGGRNVLGAMRRAVEVNFIDNENQESQGIYLFTSGVPDQDLHTVSAYLSEATSGSDLQLHVCLFSVGEMNVEDLTEDTNNTTGILKDLAHISNGRFHWFDEKGLIESDDISFLISEMEKA 470
BLAST of von Willebrand factor A domain containing 3B vs. Ensembl Xenopus
Match: muc4 (mucin 4, cell surface associated [Source:Xenbase;Acc:XB-GENE-852599]) HSP 1 Score: 143.28 bits (360), Expect = 1.264e-35 Identity = 89/321 (27.73%), Postives = 155/321 (48.29%), Query Frame = 3
Query: 1137 EIEEAKALINQIKSLINQIPEKKGIYDNHYHHKHPLRVWNHAY---GQKEWESCCSYKKPHPCRYCVDD-NSQSKLAVHIPREEYMSSQEWLAKYGLKSRKLDFFDVLSGVCFRHCDGVVDVLEPPPVDKLDFMEQQNATLHQKLINAKYCDKFAHVKWKDGSLVHVQMSSDVHRLYSERMKLCLLAITRRIEWLRQGSRELFGTIMEDQVYILIDISASMEPHISFVKDKLYTLIQEQLRHKSKINFVAFNTKALPWRDRLVDVTEANLKSAWQWLEGLTCQGSTNTLSALQFAI-------KDRNCQGIYLLTDGRPDQ 2066
+++E +L+ + S +Q E Y +++ A+ GQ + CS+ P + N L + IP +S EWL K GLK++KL + +L+ + + V +L+ + ++TLH++ +W DG++ ++ + V R Y ++ +RI+WL GSR L+G + E +V +L+DIS S HI ++ L L++EQ+ +K N +AF ++ W+ +V T NL+ AW+W+ L C+G N L A++ A+ +++ QGIYL T G PDQ
Sbjct: 97 QVQELDSLVIVVSSCPDQTEEALSDYIQQCTIGRTIQIHIIAFDSLGQVIYLCACSWGNVSPSAFLPKPPNHDGPLNIEIPNFSPKTSAEWLKKNGLKAKKLSLYQILAPNAYSLVEEFVPILQ----------KTVSSTLHER--------AMMQFEWHDGTVKNIHVDPPVLREYQRQLAKMARTYEKRIDWLTNGSRRLWGAVCEKRVVLLVDISLSNSMHIIHIQHSLRLLLEEQMSNKDLFNIIAFGSEITSWKSEMVPPTAENLQRAWKWVLSLNCEGGRNVLGAMRRAVEVNFIDNENQESQGIYLFTSGVPDQ 399 HSP 2 Score: 67.781 bits (164), Expect = 8.766e-11 Identity = 53/217 (24.42%), Postives = 101/217 (46.54%), Query Frame = 3
Query: 213 SSEQWLNKFGLKASNLDSSSLYPRLGFARLEGFNDVLKKPIHSRYGDNLFPKHFREDGLTFNVVAKKEKLLQVQQELENAVQLYQQRLEWLSSESRRLFGVIEEHCVTXXXXXXXXXXRDFDQFICAIERFLNEQIRCIAKFNLIRVQENKCQLSNNLLPVSKDNLANGIDWLWQIDRTSATNSANLVEALIRA-------SNNKENEALYLITEDL 842
+S +WL K GLKA L + ++ +E F +L+K + S + + DG N+ L + Q++L + Y++R++WL++ SRRL+G + E V +++DI N ++ L EQ+ FN+I + ++P + +NL W+ ++ N++ A+ RA + N+E++ +YL T +
Sbjct: 183 TSAEWLKKNGLKAKKLSLYQILAPNAYSLVEEFVPILQKTVSSTLHERAMMQFEWHDGTVKNIHVDPPVLREYQRQLAKMARTYEKRIDWLTNGSRRLWGAVCEKRVVLLVDISLSNSMHIIHIQHSLRLLLEEQMSNKDLFNIIAFGSEITSWKSEMVPPTAENLQRAWKWVLSLN---CEGGRNVLGAMRRAVEVNFIDNENQESQGIYLFTSGV 396
BLAST of von Willebrand factor A domain containing 3B vs. Ensembl Mouse
Match: Vwa3b (von Willebrand factor A domain containing 3B [Source:MGI Symbol;Acc:MGI:1918103]) HSP 1 Score: 499.975 bits (1286), Expect = 8.105e-150 Identity = 369/1215 (30.37%), Postives = 584/1215 (48.07%), Query Frame = 3
Query: 210 VSSEQWLNKFGLKASNLDSSSLYPRLGFARLEGFNDVLKKPIHSRYGDNLFPKHFR-EDGLTFNVVAKKEKLLQVQQELENAVQLYQQRLEWLSSESRRLFGVIEEHCVTXXXXXXXXXXRDFDQFICAIERFLNEQIRCIAKFNLIRVQENKCQLSNNLLPVSKDNLANGIDWLWQID-RTSATNSANLVEALIRASNNKENEALYLITEDLSSDGSREVLREKVKQLKIPLNIISYNCKDPEFISYLKCLVLMTGGRFHSYLFNLEVDAYESSPLDSENPKANLLL-KKKVYGGSIGGIGTRNDCVAVFSEIEEAKALINQIKSLINQIPEKKGIYDNHYHHKHPLRVWNHAYGQKEWESCCSYKKPHPCRYCVDDNSQSKLAVHIPREEYMSSQEWLAKYGLKSRKLDFFDVLSGVCFRHCDGVVDVLEPPPVDKLDFMEQQNATLHQKLINAKYCDKFAHVKWKDGSLVHVQMSSDVHRLYSERMKLCLLAITRRIEWLRQGSRELFGTIMEDQVYILIDISASMEPHISFVKDKLYTLIQEQLRHKSKINFVAFNTKALPWRDRLVDVTEANLKSAWQWLEGLTCQGSTNTLSALQFAIKDRNCQGIYLLTDGRPDQPTKTVLSQIRLQYRLPIHTISFNCADLEANTFLCELARETGGRFHYFNEISGGADCTNENELEAWESEDIKLLKSEYRLGFDSLEKVTKLRDECHKLAW------KSEVVRKKEQKSTRKTMAPGCNQNPYFSQISPSRPKCENREIKYPRPIKAKNTFRKQQKEQENDPIWSGTIKLLNLDSTTVASQSDAYQSFLEALSSRDENEQEWVIDETQEIIDRQTERYKKILEDEYNEAMSXXXXXXXXXXXXXXXXXXXQWLHIYGLVPQHMTILDALAPTIVKVRPKYVPIIDKYVMSKVFEEILPISHVVTEGSPKRGYKPVVRLVNPLAVDLKAYQEKLENLMNKYRKKLRKLIQIHIGDSTLNAFDEMLVKYPLGNDDVKRWVMKAFRDANWPMGEEELEMFMNEIYIGQKYFIQAGDLLRIRGKTGPGKGGKDETPEFEPFDGELQNTNEPFSKV---LLAAMKGATILAPGPEDGYYYDAQIINWPNCDFVDVQFNMFAGITSVPVPDCVILPEKYA----RITAGMTALIKVYNMDNDRTFYLPGIITSSKIVHPGLNEERYHVTLYNGLESTVRPDEVVAISKENY 3806
+SSE+WL GLK+ L + ++GF + E + L++ + SRY D LFP+ + EDG +N+ AK E + Q L AV+ Y+QR++WL+S SR++FGVI E VTI++D + + + A++ L EQ+ I +FN+I V + + V++ ++A I W+ ++ + ++AL+ A +K EA+Y +++L V ++ P+ +S+N + E I++LK L T RFH++ E + + S +E ++ +K+ G G G R D ++ E+EEA ++ Q++SL+++ P+ S P C+ ++ ++ E+ SQ+WL KYGLK++KL F+DVL+ FRH DGVVD+ P + + Q +A ++K I+AKYC +F H+ WKDGSLVHV ++ + ++ Y ER+ L I RRI+WL+ GS LFG + +Y+LID S SM+ ++ VKDK+ IQEQLR+KSK NFV F+ +A+ WR++L +V E NLK A W+ G+ STNTL+AL+ A D Q IYLLTDGRPDQP + V+ ++L +PI ISF+ D AN FL ELA TGG F +N G D + + ED+ LL E G LEK+ +L E + W ++ +KE S T N P ++ S P K+ K QK+ K+L+ +ST + +F + + N + K L+D+ +E+ S + WL +GLV + +TI DALA +V YVPI++K V+SKVF+E+ P++HV + + L+NP ++L Y++ +E + Y K L K++ + + D + L N DV + KA NWP+ +EL + NEI +G+ Y QA +L K K +++ +LQ P K+ L +KG ++A E+G+Y+ + + V F G T V VP I+P A ++ G K+ FY+P I+ + H +E+ Y V N ++ IS+ Y
Sbjct: 7 LSSERWLQLHGLKSKKLTLKQILSQIGFPQSEDYVTSLRRLVASRYADGLFPQIYTAEDGRLYNLTAKTELICQFVDYLTQAVESYKQRMDWLTSGSRQIFGVILEQRVTIVLDFGDVLMEELNLCRDALKMVLQEQVALITRFNMIWVSAEPVKWQEYAILVTEHSIAAAISWIEKMTFEPKPVREVSGLDALLEAGKDKTIEAIYYFVVGDVPQEFQKLLLTGVLEIPYPVCTVSFNARGEETIAFLKDLSTKTHSRFHAFAERTECEEF--SAFSTEGVDGSMTWNSRKLKGRLPPGAGVREDVFLIWREMEEACRILAQVRSLVDKAPQ-------------------------------SDVSPADCKSRPAESKENA-------EDTWESQKWLQKYGLKAQKLTFYDVLAHCSFRHADGVVDIKAKPENESV----QTSADTNKKTIHAKYCSRFIHIPWKDGSLVHVNITKEKYKWYRERIHTALAMIQRRIKWLQNGSHILFGKARGECIYVLIDTSCSMKSRLNLVKDKIIQFIQEQLRYKSKFNFVTFDGQAIAWREKLAEVNEDNLKQAQSWIRGIKVGSSTNTLNALKIAFADEETQVIYLLTDGRPDQPPEMVMDHVKLFQNIPICAISFSYNDEVANEFLKELAALTGGEFRAYN--FGCKDPIQDT-----QDEDLNLLLQEMEQGHSDLEKMQELYMESLVVDWWYNADKDTDSKHQKEILSMVSTPEERANSQPDADSLASSPPNVSTGSWKFLE--------EKTQKK-----------KILHAESTKTSLLRSHISNFKSSSNKDSSNSSSRSHTSALSNREMSVLLTNKCLDDKLSESASGNGSQVSGHTSSDTSSKT--WLQTHGLVAKKLTIADALAGAMVPHSSTYVPILNKNVVSKVFDEVFPLAHVCNNSNK-------MVLINPHGINLNIYKQNVEQAIKSYEKCLNKIVWQALSEEEKEKLDAIKPIQYLENKDV---LNKALERLNWPISLKELSVLENEILVGKMYIQQALELQETSRKNYQSKTLQEQQ--------KLQGY--PTKKIKSRKLDPLKGQKVIARCEENGFYFPGVVKKCVSSSHALVDFRY--GDTKV-VPISFIMPVGGAMPCPQLQVGDYVFAKIMT-SKGFDFYVPAIVIALP-NHNVASEKFYTVLKCNNRREFCPRSALIKISQNKY 1124 HSP 2 Score: 119.398 bits (298), Expect = 3.459e-26 Identity = 80/311 (25.72%), Postives = 152/311 (48.87%), Query Frame = 3
Query: 1362 IPREEYMSSQEWLAKYGLKSRKLDFFDVLSGVCFRHCDGVVDVLEPPPVDKLDFMEQQNATLHQKLINAKYCDK-FAHV-KWKDGSLVHVQMSSDVHRLYSERMKLCLLAITRRIEWLRQGSRELFGTIMEDQVYILIDISASMEPHISFVKDKLYTLIQEQLRHKSKINFVAFNTKALPWRDRLVDVTEANLKSAWQWLEGLTCQG----STNTLSALQFAIKDRNCQGIYLLTDGRPDQPTKTVLSQIRLQYRLPIHTISFNCADLEANTFLCELARETGGRFHYFNEISGGADCTNENELEAWESEDI 2276
+ + +SS+ WL +GLKS+KL +LS + F + V L ++L+ ++Y D F + +DG L ++ +++ + + + + + +R++WL GSR++FG I+E +V I++D + ++ +D L ++QEQ+ ++ N + + + + W++ + VTE ++ +A W+E +T + + L AL A KD+ + IY G Q + +L L+ P+ T+SFN E FL +L+ +T RFH F A+ T E A+ +E +
Sbjct: 1 MAEQSLLSSERWLQLHGLKSKKLTLKQILSQIGFPQSEDYVTSL-------------------RRLVASRYADGLFPQIYTAEDGRLYNLTAKTELICQFVDYLTQAVESYKQRMDWLTSGSRQIFGVILEQRVTIVLDFGDVLMEELNLCRDALKMVLQEQVALITRFNMIWVSAEPVKWQEYAILVTEHSIAAAISWIEKMTFEPKPVREVSGLDALLEAGKDKTIEAIYYFVVGDVPQEFQKLLLTGVLEIPYPVCTVSFNARGEETIAFLKDLSTKTHSRFHAF------AERTECEEFSAFSTEGV 286
BLAST of von Willebrand factor A domain containing 3B vs. Ensembl Mouse
Match: Vwa3b (von Willebrand factor A domain containing 3B [Source:MGI Symbol;Acc:MGI:1918103]) HSP 1 Score: 499.975 bits (1286), Expect = 1.075e-149 Identity = 368/1215 (30.29%), Postives = 586/1215 (48.23%), Query Frame = 3
Query: 210 VSSEQWLNKFGLKASNLDSSSLYPRLGFARLEGFNDVLKKPIHSRYGDNLFPKHFR-EDGLTFNVVAKKEKLLQVQQELENAVQLYQQRLEWLSSESRRLFGVIEEHCVTXXXXXXXXXXRDFDQFICAIERFLNEQIRCIAKFNLIRVQENKCQLSNNLLPVSKDNLANGIDWLWQID-RTSATNSANLVEALIRASNNKENEALYLITEDLSSDGSREVLREKVKQLKIPLNIISYNCKDPEFISYLKCLVLMTGGRFHSYLFNLEVDAYESSPLDSENPKANLLL-KKKVYGGSIGGIGTRNDCVAVFSEIEEAKALINQIKSLINQIPEKKGIYDNHYHHKHPLRVWNHAYGQKEWESCCSYKKPHPCRYCVDDNSQSKLAVHIPREEYMSSQEWLAKYGLKSRKLDFFDVLSGVCFRHCDGVVDVLEPPPVDKLDFMEQQNATLHQKLINAKYCDKFAHVKWKDGSLVHVQMSSDVHRLYSERMKLCLLAITRRIEWLRQGSRELFGTIMEDQVYILIDISASMEPHISFVKDKLYTLIQEQLRHKSKINFVAFNTKALPWRDRLVDVTEANLKSAWQWLEGLTCQGSTNTLSALQFAIKDRNCQGIYLLTDGRPDQPTKTVLSQIRLQYRLPIHTISFNCADLEANTFLCELARETGGRFHYFNEISGGADCTNENELEAWESEDIKLLKSEYRLGFDSLEKVTKLRDECHKLAW------KSEVVRKKEQKSTRKTMAPGCNQNPYFSQISPSRPKCENREIKYPRPIKAKNTFRKQQKEQENDPIWSGTIKLLNLDSTTVASQSDAYQSFLEALSSRDENEQEWVIDETQEIIDRQTERYKKILEDEYNEAMSXXXXXXXXXXXXXXXXXXXQWLHIYGLVPQHMTILDALAPTIVKVRPKYVPIIDKYVMSKVFEEILPISHVVTEGSPKRGYKPVVRLVNPLAVDLKAYQEKLENLMNKYRKKLRKLIQIHIGDSTLNAFDEMLVKYPLGNDDVKRWVMKAFRDANWPMGEEELEMFMNEIYIGQKYFIQAGDLLRIRGKTGPGKGGKDETPEFEPFDGELQNTNEPFSKV---LLAAMKGATILAPGPEDGYYYDAQIINWPNCDFVDVQFNMFAGITSVPVPDCVILPEKYA----RITAGMTALIKVYNMDNDRTFYLPGIITSSKIVHPGLNEERYHVTLYNGLESTVRPDEVVAISKENY 3806
+SSE+WL GLK+ L + ++GF + E + L++ + SRY D LFP+ + EDG +N+ AK E + Q L AV+ Y+QR++WL+S SR++FGVI E VTI++D + + + A++ L EQ+ I +FN+I V + + V++ ++A I W+ ++ + ++AL+ A +K EA+Y +++L V ++ P+ +S+N + E I++LK L T RFH++ E + + S +E ++ +K+ G G G R D ++ E+EEA ++ Q++SL+++ P+ S P C+ ++ ++ E+ SQ+WL KYGLK++KL F+DVL+ FRH DGVVD+ P + + Q +A ++K I+AKYC +F H+ WKDGSLVHV ++ + ++ Y ER+ L I RRI+WL+ GS LFG + +Y+LID S SM+ ++ VKDK+ IQEQLR+KSK NFV F+ +A+ WR++L +V E NLK A W+ G+ STNTL+AL+ A D Q IYLLTDGRPDQP + V+ ++L +PI ISF+ D AN FL ELA TGG F +N C ++ ++ + ED+ LL E G LEK+ +L E + W ++ +KE S T N P ++ S P K+ K QK+ K+L+ +ST + +F + + N + K L+D+ +E+ S + WL +GLV + +TI DALA +V YVPI++K V+SKVF+E+ P++HV + + L+NP ++L Y++ +E + Y K L K++ + + D + L N DV + KA NWP+ +EL + NEI +G+ Y QA +L K K +++ +LQ P K+ L +KG ++A E+G+Y+ + + V F G T V VP I+P A ++ G K+ FY+P I+ + H +E+ Y V N ++ IS+ Y
Sbjct: 7 LSSERWLQLHGLKSKKLTLKQILSQIGFPQSEDYVTSLRRLVASRYADGLFPQIYTAEDGRLYNLTAKTELICQFVDYLTQAVESYKQRMDWLTSGSRQIFGVILEQRVTIVLDFGDVLMEELNLCRDALKMVLQEQVALITRFNMIWVSAEPVKWQEYAILVTEHSIAAAISWIEKMTFEPKPVREVSGLDALLEAGKDKTIEAIYYFVVGDVPQEFQKLLLTGVLEIPYPVCTVSFNARGEETIAFLKDLSTKTHSRFHAFAERTECEEF--SAFSTEGVDGSMTWNSRKLKGRLPPGAGVREDVFLIWREMEEACRILAQVRSLVDKAPQ-------------------------------SDVSPADCKSRPAESKENA-------EDTWESQKWLQKYGLKAQKLTFYDVLAHCSFRHADGVVDIKAKPENESV----QTSADTNKKTIHAKYCSRFIHIPWKDGSLVHVNITKEKYKWYRERIHTALAMIQRRIKWLQNGSHILFGKARGECIYVLIDTSCSMKSRLNLVKDKIIQFIQEQLRYKSKFNFVTFDGQAIAWREKLAEVNEDNLKQAQSWIRGIKVGSSTNTLNALKIAFADEETQVIYLLTDGRPDQPPEMVMDHVKLFQNIPICAISFSYNDEVANEFLKELAALTGGEFRAYN-----FGC--KDPIQDTQDEDLNLLLQEMEQGHSDLEKMQELYMESLVVDWWYNADKDTDSKHQKEILSMVSTPEERANSQPDADSLASSPPNVSTGSWKFLE--------EKTQKK-----------KILHAESTKTSLLRSHISNFKSSSNKDSSNSSSRSHTSALSNREMSVLLTNKCLDDKLSESASGNGSQVSGHTSSDTSSKT--WLQTHGLVAKKLTIADALAGAMVPHSSTYVPILNKNVVSKVFDEVFPLAHVCNNSNK-------MVLINPHGINLNIYKQNVEQAIKSYEKCLNKIVWQALSEEEKEKLDAIKPIQYLENKDV---LNKALERLNWPISLKELSVLENEILVGKMYIQQALELQETSRKNYQSKTLQEQQ--------KLQGY--PTKKIKSRKLDPLKGQKVIARCEENGFYFPGVVKKCVSSSHALVDFRY--GDTKV-VPISFIMPVGGAMPCPQLQVGDYVFAKIMT-SKGFDFYVPAIVIALP-NHNVASEKFYTVLKCNNRREFCPRSALIKISQNKY 1124 HSP 2 Score: 119.013 bits (297), Expect = 4.787e-26 Identity = 80/311 (25.72%), Postives = 152/311 (48.87%), Query Frame = 3
Query: 1362 IPREEYMSSQEWLAKYGLKSRKLDFFDVLSGVCFRHCDGVVDVLEPPPVDKLDFMEQQNATLHQKLINAKYCDK-FAHV-KWKDGSLVHVQMSSDVHRLYSERMKLCLLAITRRIEWLRQGSRELFGTIMEDQVYILIDISASMEPHISFVKDKLYTLIQEQLRHKSKINFVAFNTKALPWRDRLVDVTEANLKSAWQWLEGLTCQ----GSTNTLSALQFAIKDRNCQGIYLLTDGRPDQPTKTVLSQIRLQYRLPIHTISFNCADLEANTFLCELARETGGRFHYFNEISGGADCTNENELEAWESEDI 2276
+ + +SS+ WL +GLKS+KL +LS + F + V L ++L+ ++Y D F + +DG L ++ +++ + + + + + +R++WL GSR++FG I+E +V I++D + ++ +D L ++QEQ+ ++ N + + + + W++ + VTE ++ +A W+E +T + + L AL A KD+ + IY G Q + +L L+ P+ T+SFN E FL +L+ +T RFH F A+ T E A+ +E +
Sbjct: 1 MAEQSLLSSERWLQLHGLKSKKLTLKQILSQIGFPQSEDYVTSL-------------------RRLVASRYADGLFPQIYTAEDGRLYNLTAKTELICQFVDYLTQAVESYKQRMDWLTSGSRQIFGVILEQRVTIVLDFGDVLMEELNLCRDALKMVLQEQVALITRFNMIWVSAEPVKWQEYAILVTEHSIAAAISWIEKMTFEPKPVREVSGLDALLEAGKDKTIEAIYYFVVGDVPQEFQKLLLTGVLEIPYPVCTVSFNARGEETIAFLKDLSTKTHSRFHAF------AERTECEEFSAFSTEGV 286
BLAST of von Willebrand factor A domain containing 3B vs. Ensembl Mouse
Match: Vwa3b (von Willebrand factor A domain containing 3B [Source:MGI Symbol;Acc:MGI:1918103]) HSP 1 Score: 418.313 bits (1074), Expect = 1.657e-126 Identity = 253/721 (35.09%), Postives = 391/721 (54.23%), Query Frame = 3
Query: 210 VSSEQWLNKFGLKASNLDSSSLYPRLGFARLEGFNDVLKKPIHSRYGDNLFPKHFR-EDGLTFNVVAKKEKLLQVQQELENAVQLYQQRLEWLSSESRRLFGVIEEHCVTXXXXXXXXXXRDFDQFICAIERFLNEQIRCIAKFNLIRVQENKCQLSNNLLPVSKDNLANGIDWLWQID-RTSATNSANLVEALIRASNNKENEALYLITEDLSSDGSREVLREKVKQLKIPLNIISYNCKDPEFISYLKCLVLMTGGRFHSYLFNLEVDAYESSPLDSENPKANLLL-KKKVYGGSIGGIGTRNDCVAVFSEIEEAKALINQIKSLINQIPEKKGIYDNHYHHKHPLRVWNHAYGQKEWESCCSYKKPHPCRYCVDDNSQSKLAVHIPREEYMSSQEWLAKYGLKSRKLDFFDVLSGVCFRHCDGVVDVLEPPPVDKLDFMEQQNATLHQKLINAKYCDKFAHVKWKDGSLVHVQMSSDVHRLYSERMKLCLLAITRRIEWLRQGSRELFGTIMEDQVYILIDISASMEPHISFVKDKLYTLIQEQLRHKSKINFVAFNTKALPWRDRLVDVTEANLKSAWQWLEGLTCQGSTNTLSALQFAIKDRNCQGIYLLTDGRPDQPTKTVLSQIRLQYRLPIHTISFNCADLEANTFLCELARETGGRFHYFNEISGGADCTNENELEAWESEDIKLLKSEYRLGFDSLEKVTKLRDECHKLAW 2363
+SSE+WL GLK+ L + ++GF + E + L++ + SRY D LFP+ + EDG +N+ AK E + Q L AV+ Y+QR++WL+S SR++FGVI E VTI++D + + + A++ L EQ+ I +FN+I V + + V++ ++A I W+ ++ + ++AL+ A +K EA+Y +++L V ++ P+ +S+N + E I++LK L T RFH++ E + + S +E ++ +K+ G G G R D ++ E+EEA ++ Q++SL+++ P+ S P C+ ++ ++ E+ SQ+WL KYGLK++KL F+DVL+ FRH DGVVD+ P + + Q +A ++K I+AKYC +F H+ WKDGSLVHV ++ + ++ Y ER+ L I RRI+WL+ GS LFG + +Y+LID S SM+ ++ VKDK+ IQEQLR+KSK NFV F+ +A+ WR++L +V E NLK A W+ G+ STNTL+AL+ A D Q IYLLTDGRPDQP + V+ ++L +PI ISF+ D AN FL ELA TGG F +N G D + + ED+ LL E G LEK+ +L E + W
Sbjct: 7 LSSERWLQLHGLKSKKLTLKQILSQIGFPQSEDYVTSLRRLVASRYADGLFPQIYTAEDGRLYNLTAKTELICQFVDYLTQAVESYKQRMDWLTSGSRQIFGVILEQRVTIVLDFGDVLMEELNLCRDALKMVLQEQVALITRFNMIWVSAEPVKWQEYAILVTEHSIAAAISWIEKMTFEPKPVREVSGLDALLEAGKDKTIEAIYYFVVGDVPQEFQKLLLTGVLEIPYPVCTVSFNARGEETIAFLKDLSTKTHSRFHAFAERTECEEF--SAFSTEGVDGSMTWNSRKLKGRLPPGAGVREDVFLIWREMEEACRILAQVRSLVDKAPQ-------------------------------SDVSPADCKSRPAESKENA-------EDTWESQKWLQKYGLKAQKLTFYDVLAHCSFRHADGVVDIKAKPENESV----QTSADTNKKTIHAKYCSRFIHIPWKDGSLVHVNITKEKYKWYRERIHTALAMIQRRIKWLQNGSHILFGKARGECIYVLIDTSCSMKSRLNLVKDKIIQFIQEQLRYKSKFNFVTFDGQAIAWREKLAEVNEDNLKQAQSWIRGIKVGSSTNTLNALKIAFADEETQVIYLLTDGRPDQPPEMVMDHVKLFQNIPICAISFSYNDEVANEFLKELAALTGGEFRAYN--FGCKDPIQDT-----QDEDLNLLLQEMEQGHSDLEKMQELYMESLVVDW 676 HSP 2 Score: 118.242 bits (295), Expect = 3.598e-26 Identity = 76/290 (26.21%), Postives = 144/290 (49.66%), Query Frame = 3
Query: 1362 IPREEYMSSQEWLAKYGLKSRKLDFFDVLSGVCFRHCDGVVDVLEPPPVDKLDFMEQQNATLHQKLINAKYCDK-FAHV-KWKDGSLVHVQMSSDVHRLYSERMKLCLLAITRRIEWLRQGSRELFGTIMEDQVYILIDISASMEPHISFVKDKLYTLIQEQLRHKSKINFVAFNTKALPWRDRLVDVTEANLKSAWQWLEGLTCQG----STNTLSALQFAIKDRNCQGIYLLTDGRPDQPTKTVLSQIRLQYRLPIHTISFNCADLEANTFLCELARETGGRFHYFNE 2213
+ + +SS+ WL +GLKS+KL +LS + F + V L ++L+ ++Y D F + +DG L ++ +++ + + + + + +R++WL GSR++FG I+E +V I++D + ++ +D L ++QEQ+ ++ N + + + + W++ + VTE ++ +A W+E +T + + L AL A KD+ + IY G Q + +L L+ P+ T+SFN E FL +L+ +T RFH F E
Sbjct: 1 MAEQSLLSSERWLQLHGLKSKKLTLKQILSQIGFPQSEDYVTSL-------------------RRLVASRYADGLFPQIYTAEDGRLYNLTAKTELICQFVDYLTQAVESYKQRMDWLTSGSRQIFGVILEQRVTIVLDFGDVLMEELNLCRDALKMVLQEQVALITRFNMIWVSAEPVKWQEYAILVTEHSIAAAISWIEKMTFEPKPVREVSGLDALLEAGKDKTIEAIYYFVVGDVPQEFQKLLLTGVLEIPYPVCTVSFNARGEETIAFLKDLSTKTHSRFHAFAE 271
BLAST of von Willebrand factor A domain containing 3B vs. Ensembl Mouse
Match: Vwa3a (von Willebrand factor A domain containing 3A [Source:MGI Symbol;Acc:MGI:3041229]) HSP 1 Score: 166.392 bits (420), Expect = 1.326e-40 Identity = 177/723 (24.48%), Postives = 300/723 (41.49%), Query Frame = 3
Query: 216 SEQWLNKFGLKASNLDSSSLYPRLGFARLEGFNDVLKKPIHSRYGDNLFPK-HFREDGLTFNVVAKKEKLLQVQQELENAVQLYQQRLEWLSSESRRLFGVIEEHCVTXXX-XXXXXXXRDFDQFICAIERFLNEQIRCIAKFNLIRVQENKCQLSNNLLPVSKDNLANGIDWLWQIDRTSATNSANLVEALIRASNNKENEALYLITEDLSSDGSREVLREKVKQLKIP----LNIISYNCKDPEFISYLKCLVLMTGGRFHSYLFNLEVDAYESSPLDSENPKANLLLKKKVYGGSIGGIGTRNDCVAVFSEIEEAKALINQIKSLINQIPEKKGIYDNHYHHKHPLRVWNHAYGQKEWESCCSYKKPHPCRYCVDDNSQSKLAVHIPREEYMSSQEWLAKYGLKSRKLDFFDVLSGVCFRHCDGVVDVLEPPPVDKLDFMEQQNATLHQKLINAKYCDKFAHVKWKDGSLVHVQMSSDVHRLYSERMKLCLLAITRRIEWLRQGSRELFGTIMEDQVYILIDISASMEPHISFVKDKLYTLIQEQLRHKSKINFVAFNTKALPWRDRLVDVTEANLKSAWQWLEGLTCQGSTNTLSALQFAI----KDRN---CQGIYLLTDGRPDQPTKTVLSQIRLQYR---LPIHTISFNCADLEANTF--LC------------ELARETGGRFHYFNEISGGADCTNENELEAWESEDIKLLKSE 2294
SE WL LK L + L + G LE N N PK HF + + + L + ++LYQQR+ WL+ S++ FG+I+ V ++I + + +F + ++EQ+ K ++ L + + VS L W + S+NL++AL + +KE +L +I D E L + ++Q + +++ +Y C D + LK L GG +H Y +P++ L T D V + E +A+ L++Q+++L H +P + + E K P ++ L + P + S+ EWL GLK++KL + VL+ F + V +L+ + AT+H+K + +W DG++ ++ + V Y +++ + R++WL SR ++GT+ + +V IL+D+S + +I ++ L L++EQL +K N +AF + WR +V V+ NL+ AW+W GL CQGS N L AL+ AI KD+N QGIYL T G PDQ + + + Y L ++ F + + +T C E+ + GRFH+F E +ES+DI + SE
Sbjct: 63 SEDWLAMHSLKFEKLTLADLISQ-GTVELEDCN-------------NAVPKVHF-----------TTQTIHHFKSRLSDTIELYQQRMRWLTENSKKAFGLIKGSRVGLLIDSSQVSSGSQTKEFQNDLTGLIDEQLSLKEKLYVLSFGVTINPLWPDPMEVSTSTLQELKLW---VKTLQPEGSSNLLQALKKVFAHKELNSLVIILRS-CPDQPSEFLSDFIQQSTLGRSVFIHVTTYKCDDHVPSAVLKNLTDALGGYYHCY-----------------SPESELY--------------TSRDVVELQVETHKAQGLLSQVQALC---------------HNNPCEELSCMIKEISIEIA---KGPFTSLLPKPPKHEAPLTIKFPDLDKTSA-EWLKINGLKAKKLSLYQVLAPNAFNPVEEFVPILQ----------KTVAATIHEKAM--------VQFEWHDGTVKNIHVDPPVLFEYQKQLGKAVQIYEHRLQWLSLTSRRIWGTVCQRRVVILLDVSVTNSMYIIHIQHSLRLLLEEQLSNKDYFNIIAFGSTIESWRPEMVAVSHDNLQRAWRWALGLQCQGSRNVLGALRKAIEVDFKDKNKHESQGIYLFTGGIPDQDVHILSAYVAEAYGGCDLQLNVCLFYVGEPQMDTTPPACYASRTDTATAYKEITQAARGRFHWFGETG------------IYESDDINAIVSE 676 HSP 2 Score: 161.384 bits (407), Expect = 3.788e-39 Identity = 115/349 (32.95%), Postives = 175/349 (50.14%), Query Frame = 3
Query: 1353 AVHIPREEYM-SSQEWLAKYGLKSRKLDFFDVLSGVCFRHCDGVVDVLEPPPVDKLDFMEQQNATLHQKLINAKYCDKFAHVKWKDGSLVHVQMSSDVHRLYSERMKLCLLAITRRIEWLRQGSRELFGTIMEDQVYILIDISASMEPHISFVKDKLYTLIQEQLR-HKSKINFVAFNTKALPWRDRLVDVTEANLKSAWQWLEGLTCQGSTNTLSALQFAIKDRNCQGIYLLTDGRPDQPTKTVLSQIRL---QYRLPIHTISFNCADLEANTFLCELARETGGRFH------YFNEISG----GADCTNENELEAWESEDIKLLKSEYRLGFDSLEKVTKLRDECHK 2354
++ +PR++ + SSQEW A LK KL+ L C R+ V P + A++C F ++ +G + H+Q + Y M+ +R+ WL GSR LFGTI+E V IL+D S SM PH+ ++K +L LI EQLR H ++ N ++F W+D LV+ TEA A QW+ L QGST+ L+AL A ++ QG+YLLTDG+PD +L+ ++ + + +HTIS AD A FL ELA +GGR+H + I G G + +L +E +D++LL E+ + L++ R + K
Sbjct: 814 SIQLPRKDTVCSSQEWTATCRLKRLKLELSKCLGPNC-RYQKSV----RGPAL-------------------AEHCTLFPSIEI-NGVVRHIQWTLWEMETYITCMEKVTRCYVQRLHWLLSGSRRLFGTILERNVCILLDTSGSMGPHLQWIKTELVLLIWEQLRKHCARFNLLSFAEDLQLWQDTLVESTEAACHKAMQWVAHLQAQGSTSVLAALTKAFSFQDVQGLYLLTDGKPDTSCSLILNTVQSFQKERGVKVHTISLTSADRTATEFLRELASLSGGRYHCPVSDKALSGIQGLLTRGFIKERDPKLPLFEGDDLRLLAEEFTRARNLLKQAQVFRSQLLK 1137 HSP 3 Score: 77.0258 bits (188), Expect = 2.635e-13 Identity = 86/329 (26.14%), Postives = 136/329 (41.34%), Query Frame = 3
Query: 1386 SQEWLAKYGLKSRKLDFFDVLS--GVCFRHCDGVVDVLEPPPVDKLDFMEQQNATLHQKLINAKYCDKFAHVKWKDGSLVHVQMSSDVHRLYSERMKLCLLAITRRIEWLRQGSRELFGTIMEDQVYILIDIS-ASMEPHISFVKDKLYTLIQEQLRHKSKINFVAFNTKALP-WRDRLVDVTEANLKSAWQWLEGLTCQGSTNTLSALQFAIKDRNCQGIYLLTDGRPDQPTKTV---LSQIRLQYRLPIHTISFNCADLEANTFLCELARETGGRFHYFNEISGGADCTNENELEAWESEDIKLLKSEYRLGFDSLEKVTKLRDECH 2351
S++WLA + LK KL D++S V C+ V K+ F Q T+H H K + SD LY +RM+ WL + S++ FG I +V +LID S S ++ L LI EQL K K+ ++F P W D + +V+ + L+ W++ L +GS+N L AL+ + + ++ PDQP++ + + Q L + IH ++ C D + L L GG +H ++ E E + S D+ L+ E L +V L CH
Sbjct: 63 SEDWLAMHSLKFEKLTLADLISQGTVELEDCNNAVP--------KVHFTTQ---TIH-------------HFKSR---------LSDTIELYQQRMR-----------WLTENSKKAFGLIKGSRVGLLIDSSQVSSGSQTKEFQNDLTGLIDEQLSLKEKLYVLSFGVTINPLWPDPM-EVSTSTLQELKLWVKTLQPEGSSNLLQALKKVFAHKELNSLVIILRSCPDQPSEFLSDFIQQSTLGRSVFIHVTTYKCDDHVPSAVLKNLTDALGGYYHCYSP-----------ESELYTSRDVVELQVETHKAQGLLSQVQAL---CH 332 HSP 4 Score: 70.8626 bits (172), Expect = 1.814e-11 Identity = 63/227 (27.75%), Postives = 101/227 (44.49%), Query Frame = 3
Query: 174 PTKVWNPDAKLQVSSEQWLNKFGLKASNLDSSSLYPRLGFARLEGFNDVLKKPIHSRYGDNLFPKHFREDGLTFNVVAKKEKLLQVQQELENAVQLYQQRLEWLSSESRRLFGVIEEHCVTXXXXXXXXXXRDFDQFICAIERFLNEQIRCIAKFNLIRVQENKCQLSNNLLPVSKDNLANGIDWLWQIDRTSATNSANLVEALIRA-------SNNKENEALYLIT 833
P + PD L +S +WL GLKA L + F +E F +L+K + + + + DG N+ L + Q++L AVQ+Y+ RL+WLS SRR++G + + V I++D+ N ++ L EQ+ FN+I ++ VS DNL W W + S N++ AL +A N E++ +YL T
Sbjct: 368 PLTIKFPD--LDKTSAEWLKINGLKAKKLSLYQVLAPNAFNPVEEFVPILQKTVAATIHEKAMVQFEWHDGTVKNIHVDPPVLFEYQKQLGKAVQIYEHRLQWLSLTSRRIWGTVCQRRVVILLDVSVTNSMYIIHIQHSLRLLLEEQLSNKDYFNIIAFGSTIESWRPEMVAVSHDNLQRA--WRWALG-LQCQGSRNVLGALRKAIEVDFKDKNKHESQGIYLFT 589 HSP 5 Score: 63.1586 bits (152), Expect = 4.535e-9 Identity = 53/188 (28.19%), Postives = 90/188 (47.87%), Query Frame = 3
Query: 441 LENAVQLYQQRLEWLSSESRRLFGVIEEHCVTXXXXXXXXXXRDFDQFICAIERFLNEQIR--CIAKFNLIRVQENKCQLSNNLLPVSKDNLANGIDWLWQIDRTSATNSANLVEALIRASNNKENEALYLITEDLSSDGSREVLREKV----KQLKIPLNIISYNCKDPEFISYLKCLVLMTGGRFH 986
+E + Y QRL WL S SRRLFG I E V I++D + + EQ+R C A+FNL+ E+ + L+ ++ + W+ + A S +++ AL +A + ++ + LYL+T D D S ++ V K+ + ++ IS D +L+ L ++GGR+H
Sbjct: 894 MEKVTRCYVQRLHWLLSGSRRLFGTILERNVCILLDTSGSMGPHLQWIKTELVLLIWEQLRKHC-ARFNLLSFAEDLQLWQDTLVESTEAACHKAMQWVAHLQ---AQGSTSVLAALTKAFSFQDVQGLYLLT-DGKPDTSCSLILNTVQSFQKERGVKVHTISLTSADRTATEFLRELASLSGGRYH 1076
BLAST of von Willebrand factor A domain containing 3B vs. Ensembl Mouse
Match: Vwa3a (von Willebrand factor A domain containing 3A [Source:MGI Symbol;Acc:MGI:3041229]) HSP 1 Score: 166.392 bits (420), Expect = 1.326e-40 Identity = 177/723 (24.48%), Postives = 300/723 (41.49%), Query Frame = 3
Query: 216 SEQWLNKFGLKASNLDSSSLYPRLGFARLEGFNDVLKKPIHSRYGDNLFPK-HFREDGLTFNVVAKKEKLLQVQQELENAVQLYQQRLEWLSSESRRLFGVIEEHCVTXXX-XXXXXXXRDFDQFICAIERFLNEQIRCIAKFNLIRVQENKCQLSNNLLPVSKDNLANGIDWLWQIDRTSATNSANLVEALIRASNNKENEALYLITEDLSSDGSREVLREKVKQLKIP----LNIISYNCKDPEFISYLKCLVLMTGGRFHSYLFNLEVDAYESSPLDSENPKANLLLKKKVYGGSIGGIGTRNDCVAVFSEIEEAKALINQIKSLINQIPEKKGIYDNHYHHKHPLRVWNHAYGQKEWESCCSYKKPHPCRYCVDDNSQSKLAVHIPREEYMSSQEWLAKYGLKSRKLDFFDVLSGVCFRHCDGVVDVLEPPPVDKLDFMEQQNATLHQKLINAKYCDKFAHVKWKDGSLVHVQMSSDVHRLYSERMKLCLLAITRRIEWLRQGSRELFGTIMEDQVYILIDISASMEPHISFVKDKLYTLIQEQLRHKSKINFVAFNTKALPWRDRLVDVTEANLKSAWQWLEGLTCQGSTNTLSALQFAI----KDRN---CQGIYLLTDGRPDQPTKTVLSQIRLQYR---LPIHTISFNCADLEANTF--LC------------ELARETGGRFHYFNEISGGADCTNENELEAWESEDIKLLKSE 2294
SE WL LK L + L + G LE N N PK HF + + + L + ++LYQQR+ WL+ S++ FG+I+ V ++I + + +F + ++EQ+ K ++ L + + VS L W + S+NL++AL + +KE +L +I D E L + ++Q + +++ +Y C D + LK L GG +H Y +P++ L T D V + E +A+ L++Q+++L H +P + + E K P ++ L + P + S+ EWL GLK++KL + VL+ F + V +L+ + AT+H+K + +W DG++ ++ + V Y +++ + R++WL SR ++GT+ + +V IL+D+S + +I ++ L L++EQL +K N +AF + WR +V V+ NL+ AW+W GL CQGS N L AL+ AI KD+N QGIYL T G PDQ + + + Y L ++ F + + +T C E+ + GRFH+F E +ES+DI + SE
Sbjct: 63 SEDWLAMHSLKFEKLTLADLISQ-GTVELEDCN-------------NAVPKVHF-----------TTQTIHHFKSRLSDTIELYQQRMRWLTENSKKAFGLIKGSRVGLLIDSSQVSSGSQTKEFQNDLTGLIDEQLSLKEKLYVLSFGVTINPLWPDPMEVSTSTLQELKLW---VKTLQPEGSSNLLQALKKVFAHKELNSLVIILRS-CPDQPSEFLSDFIQQSTLGRSVFIHVTTYKCDDHVPSAVLKNLTDALGGYYHCY-----------------SPESELY--------------TSRDVVELQVETHKAQGLLSQVQALC---------------HNNPCEELSCMIKEISIEIA---KGPFTSLLPKPPKHEAPLTIKFPDLDKTSA-EWLKINGLKAKKLSLYQVLAPNAFNPVEEFVPILQ----------KTVAATIHEKAM--------VQFEWHDGTVKNIHVDPPVLFEYQKQLGKAVQIYEHRLQWLSLTSRRIWGTVCQRRVVILLDVSVTNSMYIIHIQHSLRLLLEEQLSNKDYFNIIAFGSTIESWRPEMVAVSHDNLQRAWRWALGLQCQGSRNVLGALRKAIEVDFKDKNKHESQGIYLFTGGIPDQDVHILSAYVAEAYGGCDLQLNVCLFYVGEPQMDTTPPACYASRTDTATAYKEITQAARGRFHWFGETG------------IYESDDINAIVSE 676 HSP 2 Score: 161.384 bits (407), Expect = 3.788e-39 Identity = 115/349 (32.95%), Postives = 175/349 (50.14%), Query Frame = 3
Query: 1353 AVHIPREEYM-SSQEWLAKYGLKSRKLDFFDVLSGVCFRHCDGVVDVLEPPPVDKLDFMEQQNATLHQKLINAKYCDKFAHVKWKDGSLVHVQMSSDVHRLYSERMKLCLLAITRRIEWLRQGSRELFGTIMEDQVYILIDISASMEPHISFVKDKLYTLIQEQLR-HKSKINFVAFNTKALPWRDRLVDVTEANLKSAWQWLEGLTCQGSTNTLSALQFAIKDRNCQGIYLLTDGRPDQPTKTVLSQIRL---QYRLPIHTISFNCADLEANTFLCELARETGGRFH------YFNEISG----GADCTNENELEAWESEDIKLLKSEYRLGFDSLEKVTKLRDECHK 2354
++ +PR++ + SSQEW A LK KL+ L C R+ V P + A++C F ++ +G + H+Q + Y M+ +R+ WL GSR LFGTI+E V IL+D S SM PH+ ++K +L LI EQLR H ++ N ++F W+D LV+ TEA A QW+ L QGST+ L+AL A ++ QG+YLLTDG+PD +L+ ++ + + +HTIS AD A FL ELA +GGR+H + I G G + +L +E +D++LL E+ + L++ R + K
Sbjct: 814 SIQLPRKDTVCSSQEWTATCRLKRLKLELSKCLGPNC-RYQKSV----RGPAL-------------------AEHCTLFPSIEI-NGVVRHIQWTLWEMETYITCMEKVTRCYVQRLHWLLSGSRRLFGTILERNVCILLDTSGSMGPHLQWIKTELVLLIWEQLRKHCARFNLLSFAEDLQLWQDTLVESTEAACHKAMQWVAHLQAQGSTSVLAALTKAFSFQDVQGLYLLTDGKPDTSCSLILNTVQSFQKERGVKVHTISLTSADRTATEFLRELASLSGGRYHCPVSDKALSGIQGLLTRGFIKERDPKLPLFEGDDLRLLAEEFTRARNLLKQAQVFRSQLLK 1137 HSP 3 Score: 77.0258 bits (188), Expect = 2.635e-13 Identity = 86/329 (26.14%), Postives = 136/329 (41.34%), Query Frame = 3
Query: 1386 SQEWLAKYGLKSRKLDFFDVLS--GVCFRHCDGVVDVLEPPPVDKLDFMEQQNATLHQKLINAKYCDKFAHVKWKDGSLVHVQMSSDVHRLYSERMKLCLLAITRRIEWLRQGSRELFGTIMEDQVYILIDIS-ASMEPHISFVKDKLYTLIQEQLRHKSKINFVAFNTKALP-WRDRLVDVTEANLKSAWQWLEGLTCQGSTNTLSALQFAIKDRNCQGIYLLTDGRPDQPTKTV---LSQIRLQYRLPIHTISFNCADLEANTFLCELARETGGRFHYFNEISGGADCTNENELEAWESEDIKLLKSEYRLGFDSLEKVTKLRDECH 2351
S++WLA + LK KL D++S V C+ V K+ F Q T+H H K + SD LY +RM+ WL + S++ FG I +V +LID S S ++ L LI EQL K K+ ++F P W D + +V+ + L+ W++ L +GS+N L AL+ + + ++ PDQP++ + + Q L + IH ++ C D + L L GG +H ++ E E + S D+ L+ E L +V L CH
Sbjct: 63 SEDWLAMHSLKFEKLTLADLISQGTVELEDCNNAVP--------KVHFTTQ---TIH-------------HFKSR---------LSDTIELYQQRMR-----------WLTENSKKAFGLIKGSRVGLLIDSSQVSSGSQTKEFQNDLTGLIDEQLSLKEKLYVLSFGVTINPLWPDPM-EVSTSTLQELKLWVKTLQPEGSSNLLQALKKVFAHKELNSLVIILRSCPDQPSEFLSDFIQQSTLGRSVFIHVTTYKCDDHVPSAVLKNLTDALGGYYHCYSP-----------ESELYTSRDVVELQVETHKAQGLLSQVQAL---CH 332 HSP 4 Score: 70.8626 bits (172), Expect = 1.814e-11 Identity = 63/227 (27.75%), Postives = 101/227 (44.49%), Query Frame = 3
Query: 174 PTKVWNPDAKLQVSSEQWLNKFGLKASNLDSSSLYPRLGFARLEGFNDVLKKPIHSRYGDNLFPKHFREDGLTFNVVAKKEKLLQVQQELENAVQLYQQRLEWLSSESRRLFGVIEEHCVTXXXXXXXXXXRDFDQFICAIERFLNEQIRCIAKFNLIRVQENKCQLSNNLLPVSKDNLANGIDWLWQIDRTSATNSANLVEALIRA-------SNNKENEALYLIT 833
P + PD L +S +WL GLKA L + F +E F +L+K + + + + DG N+ L + Q++L AVQ+Y+ RL+WLS SRR++G + + V I++D+ N ++ L EQ+ FN+I ++ VS DNL W W + S N++ AL +A N E++ +YL T
Sbjct: 368 PLTIKFPD--LDKTSAEWLKINGLKAKKLSLYQVLAPNAFNPVEEFVPILQKTVAATIHEKAMVQFEWHDGTVKNIHVDPPVLFEYQKQLGKAVQIYEHRLQWLSLTSRRIWGTVCQRRVVILLDVSVTNSMYIIHIQHSLRLLLEEQLSNKDYFNIIAFGSTIESWRPEMVAVSHDNLQRA--WRWALG-LQCQGSRNVLGALRKAIEVDFKDKNKHESQGIYLFT 589 HSP 5 Score: 63.1586 bits (152), Expect = 4.535e-9 Identity = 53/188 (28.19%), Postives = 90/188 (47.87%), Query Frame = 3
Query: 441 LENAVQLYQQRLEWLSSESRRLFGVIEEHCVTXXXXXXXXXXRDFDQFICAIERFLNEQIR--CIAKFNLIRVQENKCQLSNNLLPVSKDNLANGIDWLWQIDRTSATNSANLVEALIRASNNKENEALYLITEDLSSDGSREVLREKV----KQLKIPLNIISYNCKDPEFISYLKCLVLMTGGRFH 986
+E + Y QRL WL S SRRLFG I E V I++D + + EQ+R C A+FNL+ E+ + L+ ++ + W+ + A S +++ AL +A + ++ + LYL+T D D S ++ V K+ + ++ IS D +L+ L ++GGR+H
Sbjct: 894 MEKVTRCYVQRLHWLLSGSRRLFGTILERNVCILLDTSGSMGPHLQWIKTELVLLIWEQLRKHC-ARFNLLSFAEDLQLWQDTLVESTEAACHKAMQWVAHLQ---AQGSTSVLAALTKAFSFQDVQGLYLLT-DGKPDTSCSLILNTVQSFQKERGVKVHTISLTSADRTATEFLRELASLSGGRYH 1076
BLAST of von Willebrand factor A domain containing 3B vs. UniProt/SwissProt
Match: sp|Q502W6|VWA3B_HUMAN (von Willebrand factor A domain-containing protein 3B OS=Homo sapiens OX=9606 GN=VWA3B PE=1 SV=3) HSP 1 Score: 538.495 bits (1386), Expect = 5.947e-162 Identity = 355/1110 (31.98%), Postives = 564/1110 (50.81%), Query Frame = 3
Query: 210 VSSEQWLNKFGLKASNLDSSSLYPRLGFARLEGFNDVLKKPIHSRYGDNLFPKHFR-EDGLTFNVVAKKEKLLQVQQELENAVQLYQQRLEWLSSESRRLFGVIEEHCVTXXXXXXXXXXRDFDQFICAIERFLNEQIRCIAKFNLIRVQENKCQLSNNLLPVSKDNLANGIDWLWQIDRTSATNSANLVEALIRASNNKENEALYLITEDLSSDGSREVLREKVKQLKIPLNIISYNCKDPEFISYLKCLVLMTGGRFHSYLFNLEVDAYESSPLDSENPKANLLL--KKKVYGGSIGGIGTRNDCVAVFSEIEEAKALINQIKSLINQIPEKKGIYDNHYHHKHPLRVWNHAYGQKEWESCCSYKKPHPCRYCVDDNSQSKLAVHIPR--EEYMSSQEWLAKYGLKSRKLDFFDVLSGVCFRHCDGVVDVLEPPPVDKLDFMEQQNATLHQKLINAKYCDKFAHVKWKDGSLVHVQMSSDVHRLYSERMKLCLLAITRRIEWLRQGSRELFGTIMEDQVYILIDISASMEPHISFVKDKLYTLIQEQLRHKSKINFVAFNTKALPWRDRLVDVTEANLKSAWQWLEGLTCQGSTNTLSALQFAIKDRNCQGIYLLTDGRPDQPTKTVLSQIRLQYRLPIHTISFNCADLEANTFLCELARETGGRFHYFNEISGGADCTNENELEAWESEDIKLLKSEYRLGFDSLEKVTKLRDECHKLAWKSEVVRKKEQKSTRKTMA----PGCNQNPYFSQISPSRPKCENREIKYPRPIKAKNTFRKQQKEQENDPIWSGTIKLLNLDSTTVASQSDAY---QSFLEALSSRDEN---EQEWVIDETQEIIDRQ-TERYKKILEDEYNEAMSXXXXXXXXXXXXXXXXXXXQWLHIYGLVPQHMTILDALAPTIVKVRPKYVPIIDKYVMSKVFEEILPISHVVTEGSPKRGYKPVVRLVNPLAVDLKAYQEKLENLMNKYRKKLRKLIQIHIGDSTLNAFDEMLVKYPLGNDDVKRWVMKAFRDANWPMGEEELEMFMNEIYIGQKYFIQAGDLLRIRGKTGPGKG-GKDETPEFEPFDGELQNTNEPFSKVLLAAMKGATILAPGPEDGYYY 3488
+SSE+WL GLK++ L + ++GF E + L +P+ SRY D LFP+ +R EDG +N+ AK E + Q + L AV+ Y+QR++WL+S+SR++FGVI E CVTI++D + + D A+ L EQ+ I +FN+IRV + + N PV++ ++A I W+ ++ + A ++AL+ A +K E++Y + S+E+L ++ ++ P+ +S+N + I++LK L T RFH++ E + P S N++ +K+ G G G R D V+ E+EEA + + QI+ L+ + P P VD S++ +V I E+ S+ WL KYGLK++KL +DVL+ FRH DGVVD+ P + + Q +A ++K ++AKYC +F H WKDGSLVHV ++ + + YSER+ L I RRI+WL+ GS+ LFG + D +YILID S SM+ + VKDK+ IQEQL++KSK NFV F+ +A+ WR++L +V E NL+ A W+ + STNTLSAL+ A D+ Q IYLLTDGRPDQP +TV+ Q++ +PI+TISFN D AN FL E+A TGG FH++N C + EA ++ED+ LL E G LEK+ L E + W + + K ++ + P P S + ++ N +K P + + +K+ E+ ++ +L S+ + + D S ALS ++ + +EW+ D++ E + R+ ++ Y D +E WL YGLV + +T++DAL+ V YVP++DK+V+SKVF+E+ P++HV + + + L+NP L Y+ K+E + Y K+L K++ + D P+ + K + +A NWP+ +EL M +EI G+ Y QA +L K K G+ + + P +P +KG ++A E+G+Y+
Sbjct: 34 ISSEKWLQLHGLKSNKLTLKQILSQIGFPHCEDYVASLGRPVASRYADGLFPQLYRAEDGRVYNLTAKSELIYQFVEHLTQAVESYKQRMDWLTSKSRQIFGVILEQCVTIVLDFGGILEGELDLCREALTMVLQEQVAHITEFNIIRVSQEPVKWQENATPVTEQSIATAISWVEKLTVELTVSEAGRLDALLEAGRDKTIESIYYFVVGDVPEESKELLLQRALEIPCPVYTVSFNARGEGTIAFLKDLSAKTHSRFHAFAERTECVEF---PAFSTKDGDNVMTWNSRKLKGKLPPGAGVREDVFLVWQEMEEACSTLAQIQRLVAE-------------------------------------PPKPDVATVDCESETT-SVEIASNPEDTWDSKTWLQKYGLKAQKLSLYDVLADCSFRHADGVVDIKAKPENESV----QTSAETNKKTVHAKYCSRFVHAPWKDGSLVHVNITKEKCKWYSERIHTALARIRRRIKWLQDGSQSLFGRLHNDCIYILIDTSHSMKSKLDLVKDKIIQFIQEQLKYKSKFNFVKFDGQAVAWREQLAEVNEDNLEQAQSWIRDIKIGSSTNTLSALKTAFADKETQAIYLLTDGRPDQPPETVIDQVKRFQEIPIYTISFNYNDEIANRFLKEVAALTGGEFHFYN-----FGCKDPTPPEAVQNEDLTLLVKEMEQGHSDLEKMQDLYSESLIMDWWYNAEKDGDSKHQKEICSMISTPEKCAKPQ-SDVDSTQTSSLNM-LKGPWGLSDQKVQKKKVLHAESTKTSLLRSQMSSLRSSACSERKDGLSNASSRRTALSDKEMSILLAEEWLDDKSSEKVTREGSQVYDHDSSDVSSE----------------------NWLKTYGLVAKKLTLMDALSVAAVPHSSTYVPVLDKHVVSKVFDEVFPLAHVCNDTNK-------MTLINPQGAKLNIYKRKVEQAIQSYEKRLNKIVWRALSQEEKEKLD---ANKPIQYLENKTVLNQALERLNWPISLKELSMLESEILAGKMYIQQAMELQEAAKKNYANKAPGEQQKLQGNPTKKTKSKRPDP--------LKGQKVIARCDENGFYF 1051 HSP 2 Score: 131.339 bits (329), Expect = 5.165e-29 Identity = 82/298 (27.52%), Postives = 149/298 (50.00%), Query Frame = 3
Query: 1335 NSQSKLAVHIPREEYMSSQEWLAKYGLKSRKLDFFDVLSGVCFRHCDGVVDVLEPPPVDKLDFMEQQNATLHQKLINAKYCDK-FAHV-KWKDGSLVHVQMSSDVHRLYSERMKLCLLAITRRIEWLRQGSRELFGTIMEDQVYILIDISASMEPHISFVKDKLYTLIQEQLRHKSKINFVAFNTKALPWRDRLVDVTEANLKSAWQWLEGLTCQ---GSTNTLSALQFAIKDRNCQGIYLLTDGRPDQPTKTVLSQIRLQYRLPIHTISFNCADLEANTFLCELARETGGRFHYFNE 2213
N+++ LA + +SS++WL +GLKS KL +LS + F HC+ V L P + ++Y D F + + +DG + ++ S++ + E + + + +R++WL SR++FG I+E V I++D +E + ++ L ++QEQ+ H ++ N + + + + W++ VTE ++ +A W+E LT + L AL A +D+ + IY G + +K +L Q L+ P++T+SFN FL +L+ +T RFH F E
Sbjct: 23 NTKTDLA----EQSLISSEKWLQLHGLKSNKLTLKQILSQIGFPHCEDYVASLGRP-------------------VASRYADGLFPQLYRAEDGRVYNLTAKSELIYQFVEHLTQAVESYKQRMDWLTSKSRQIFGVILEQCVTIVLDFGGILEGELDLCREALTMVLQEQVAHITEFNIIRVSQEPVKWQENATPVTEQSIATAISWVEKLTVELTVSEAGRLDALLEAGRDKTIESIYYFVVGDVPEESKELLLQRALEIPCPVYTVSFNARGEGTIAFLKDLSAKTHSRFHAFAE 297
BLAST of von Willebrand factor A domain containing 3B vs. UniProt/SwissProt
Match: sp|A6NCI4|VWA3A_HUMAN (von Willebrand factor A domain-containing protein 3A OS=Homo sapiens OX=9606 GN=VWA3A PE=2 SV=3) HSP 1 Score: 173.326 bits (438), Expect = 6.921e-42 Identity = 118/363 (32.51%), Postives = 181/363 (49.86%), Query Frame = 3
Query: 1353 AVHIPREEYM-SSQEWLAKYGLKSRKLDFFDVLSGVCFRHCDGVVDVLEPPPVDKLDFMEQQNATLHQKLINAKYCDKFAHVKWKDGSLVHVQMSSDVHRLYSERMKLCLLAITRRIEWLRQGSRELFGTIMEDQVYILIDISASMEPHISFVKDKLYTLIQEQLRH-KSKINFVAFNTKALPWRDRLVDVTEANLKSAWQWLEGLTCQGSTNTLSALQFAIKDRNCQGIYLLTDGRPDQPTKTVLSQI---RLQYRLPIHTISFNCADLEANTFLCELARETGGRFH----------YFNEISGGADCTNENELEAWESEDIKLLKSEYRLGFDSLEKVTKLRDECHKLAWKSEVVRKKEQK 2396
++ +PR++ + SSQEW+AKYGLK KL+ + C G Q+ +AK+C F V+ G + H+Q + +Y ++ L +R++WL GSR LFGT++E +V IL+D S SM P++ VK +L LI EQLR N ++F W+D LV+ T+A A QW+ L QGST+ L AL A + +G+YLLTDG+PD VL+++ R + + +HTIS NC+D A FL +LA TGGR+H + ++ G + L +E +D+++L E +TK R W+++ R + QK
Sbjct: 850 SIDLPRKDTVCSSQEWVAKYGLKKLKLEISRCMGPNCTHQKSG------------------------QRSASAKHCSIFPSVEIH-GVVRHIQWTPREMEVYIRHLEKVLRRYVQRLQWLLSGSRRLFGTVLESKVCILLDTSGSMGPYLQQVKTELVLLIWEQLRKCCDSFNLLSFAESFQSWQDTLVETTDAACHEAMQWVTHLQAQGSTSILQALLKAFSFHDLEGLYLLTDGKPDTSCSLVLNEVQKLREKRDVKVHTISLNCSDRAAVEFLRKLASFTGGRYHCPVGEDTLSKIHSLLTKGFINEKDPTLPPFEGDDLRILAQE----------ITKARS----FLWQAQSFRSQLQK 1173 HSP 2 Score: 168.703 bits (426), Expect = 1.785e-40 Identity = 194/811 (23.92%), Postives = 344/811 (42.42%), Query Frame = 3
Query: 216 SEQWLNKFGLKASNLDSSSLYPRLGFARLEGFNDVLKKPIHSRYGDNLFPKHFREDGLTFNVVAKKEKLLQVQQELENAVQLYQQRLEWLSSESRRLFGVIEEHCVTXXXXXXXXXXR-DFDQFICAIERFLNEQIRCIAKFNLIRVQENKCQLSNNLLPVSKDNLANGIDWLWQIDRTSATNSANLVEALIRASNNKENEALYLITEDLSSDGSREVLREKVKQLKIP----LNIISYNCKDPEFISYLKCLVLMTGGRFHSYLFNLEVDAYESSPLD---SENPKANLLLKKKVYGGSIGGIGTRNDCVAVFSEIEEAKALINQIKSLINQIPEKKGIYDNHYHHKHPLRVWNHAYGQKEWESCCSYKKPHPCRYCVDDNSQSKLAVHIPREEYMSSQEWLAKYGLKSRKLDFFDVLSGVCFRHCDGVVDVLEPPPVDKLDFMEQQNATLHQKLINAKYCDKFAHVKWKDGSLVHVQMSSDVHRLYSERMKLCLLAITRRIEWLRQGSRELFGTIMEDQVYILIDISASMEPHISFVKDKLYTLIQEQLRHKSKINFVAFNTKALPWRDRLVDVTEANLKSAWQWLEGLTCQGSTNTLSALQFAI----KDRN---CQGIYLLTDGRPDQPTKTV---LSQIRLQYRLPIHTISFNCADLEANT--------------FLCELARETGGRFHYFNEISGGADCTNENELEAWESEDIKLLKSEYRLGFDSLEK----VTKLRDECHKLAWKSEVVRKKEQ----KSTRKTMAPGCNQNPYFSQIS----PSRPKCENREIKYPRPIKAK 2516
SE WL+ LK L + L + G LE +V++K S +HF + +L + +++YQ+R++WL+ S++ FG+I+ V+I+ID+ + ++F + ++EQ+ K ++ N L + + VS L W + +NL++AL + K ++L I D E+L + ++Q + ++ I+Y C D + LK L G +H Y + +++ Y S +D +E KA LL + + + C A+ +EE I LI+ +P+ H PL + P + S+ EWL GLK++KL + VL+ F + V +L+ + ++T+H+K + +W DG++ ++ + Y +++ + RRIEWL SR ++GT+ E +V +L+DISA+ +I ++ L L++EQL +K N +AF + WR +V V+ NL+SAW+W L C+GS N LSAL+ A+ KD++ QGIYL T G PDQ T+ +++ L ++ F + + +T E+ R GGRFH+F + +ES+DI + SE + +K + L++ K+ S + ++K + +S K + P P +++S P R K + RP+ ++
Sbjct: 90 SEDWLSAHSLKCQKLTLADLISQ-GTEVLEEGTNVVQKICFS----TQIIRHF-------------------ESKLSDTIEVYQERIQWLTENSKKAFGLIKGARVSILIDVSAISSGPQKEEFQKDLMSLIDEQLSHKEKLFVLSFGTNAGSLWPDPMEVSASTLQELKLW---VKTLQPDGGSNLLQALKKIFTLKGLDSLVAIMRS-CPDQPSEILSDYIQQSTMGRDLIIHFITYRCDDQMPPAVLKNLAEAVRGYYHCY--SPKMEHYTSRDMDELLAEIQKAQSLLSH------VQALQHSSPCEALTCTMEEISTEITN-GPLISLLPKPP-------KHDAPL------------------------------------TIEFPNLDKTSA-EWLKVNGLKAKKLSLYQVLAPNAFSPVEEFVPILQ----------KTVSSTIHEKAM--------IQFEWHDGTVKNIHVDPPFLYKYQQQLSRAMRMYERRIEWLSLASRRIWGTVCEKRVVVLLDISATNSMYIIHIQHSLRLLLEEQLSNKDCFNLIAFGSTIESWRPEMVPVSHNNLQSAWRWALNLRCRGSRNVLSALRKAVEVDFKDKDKHQSQGIYLFTGGIPDQDMPTLSAYMAEACGGCDLQLNVCLFYVGEPKMDTTPPARYASHTDTAAAYKEVTRAAGGRFHWFGDTG------------IYESDDINSIMSEMEKALNYSQKCAFLMASLKNHSGKVLGSSALPKEKPKTLQLRSQPKKLCPPRPTVPLGARMSIKDDPDREKSPPLKSLKWRPLSSR 789 HSP 3 Score: 83.5741 bits (205), Expect = 2.104e-14 Identity = 73/266 (27.44%), Postives = 127/266 (47.74%), Query Frame = 3
Query: 213 SSEQWLNKFGLKASNLDSSSLYPRLGFARLEGFNDVLKKPIH---SRYGDNLFPKHFREDGLTFNVVAKKEKLLQVQQELENAVQLYQQRLEWLSSESRRLFGVIEEHCVTXXXXXXXXXXRDFDQFICAIERFLNEQIR-CIAKFNLIRVQENKCQLSNNLLPVSKDNLANGIDWLWQIDRTSATNSANLVEALIRASNNKENEALYLITEDLSSDGSREVLREKVKQLK----IPLNIISYNCKDPEFISYLKCLVLMTGGRFH 986
SS++W+ K+GLK L+ +R G N +K S ++FP G+ ++ ++ + LE ++ Y QRL+WL S SRRLFG + E V I++D Q + + EQ+R C FNL+ E+ + L+ + + W+ + A S ++++AL++A + + E LYL+T D D S ++ +V++L+ + ++ IS NC D + +L+ L TGGR+H
Sbjct: 861 SSQEWVAKYGLKKLKLE---------ISRCMGPNCTHQKSGQRSASAKHCSIFPS-VEIHGVVRHIQWTPREMEVYIRHLEKVLRRYVQRLQWLLSGSRRLFGTVLESKVCILLDTSGSMGPYLQQVKTELVLLIWEQLRKCCDSFNLLSFAESFQSWQDTLVETTDAACHEAMQWVTHLQ---AQGSTSILQALLKAFSFHDLEGLYLLT-DGKPDTSCSLVLNEVQKLREKRDVKVHTISLNCSDRAAVEFLRKLASFTGGRYH 1112 HSP 4 Score: 74.7146 bits (182), Expect = 1.010e-11 Identity = 74/303 (24.42%), Postives = 130/303 (42.90%), Query Frame = 3
Query: 204 LQVSSEQWLNKFGLKASNLDSSSLYPRLGFARLEGFNDVLKKPIHSRYGDNLFPKHFREDGLTFNVVAKKEKLLQVQQELENAVQLYQQRLEWLSSESRRLFGVIEEHCVTXXXXXXXXXXRDFDQFICAIERFLNEQIRCIAKFNLIRVQENKCQLSNNLLPVSKDNLANGIDWLWQIDRTSATNSANLVEALIRA-------SNNKENEALYLITEDLSSDGSREV---LREKVKQLKIPLNIISYNCKDPEF--------------ISYLKCLVLMTGGRFHSYLFNLEVDAYESSPLDS 1040
L +S +WL GLKA L + F+ +E F +L+K + S + + DG N+ L + QQ+L A+++Y++R+EWLS SRR++G + E V +++DI N ++ L EQ+ FNLI ++PVS +NL + W W ++ S N++ AL +A + +++ +YL T + + + E + LN+ + +P+ + K + GGRFH + + YES ++S
Sbjct: 403 LDKTSAEWLKVNGLKAKKLSLYQVLAPNAFSPVEEFVPILQKTVSSTIHEKAMIQFEWHDGTVKNIHVDPPFLYKYQQQLSRAMRMYERRIEWLSLASRRIWGTVCEKRVVVLLDISATNSMYIIHIQHSLRLLLEEQLSNKDCFNLIAFGSTIESWRPEMVPVSHNNLQSA--WRWALN-LRCRGSRNVLSALRKAVEVDFKDKDKHQSQGIYLFTGGIPDQDMPTLSAYMAEACGGCDLQLNVCLFYVGEPKMDTTPPARYASHTDTAAAYKEVTRAAGGRFHWF---GDTGIYESDDINS 699
BLAST of von Willebrand factor A domain containing 3B vs. UniProt/SwissProt
Match: sp|Q3UVV9|VWA3A_MOUSE (von Willebrand factor A domain-containing protein 3A OS=Mus musculus OX=10090 GN=Vwa3a PE=2 SV=1) HSP 1 Score: 166.392 bits (420), Expect = 9.272e-40 Identity = 177/723 (24.48%), Postives = 300/723 (41.49%), Query Frame = 3
Query: 216 SEQWLNKFGLKASNLDSSSLYPRLGFARLEGFNDVLKKPIHSRYGDNLFPK-HFREDGLTFNVVAKKEKLLQVQQELENAVQLYQQRLEWLSSESRRLFGVIEEHCVTXXX-XXXXXXXRDFDQFICAIERFLNEQIRCIAKFNLIRVQENKCQLSNNLLPVSKDNLANGIDWLWQIDRTSATNSANLVEALIRASNNKENEALYLITEDLSSDGSREVLREKVKQLKIP----LNIISYNCKDPEFISYLKCLVLMTGGRFHSYLFNLEVDAYESSPLDSENPKANLLLKKKVYGGSIGGIGTRNDCVAVFSEIEEAKALINQIKSLINQIPEKKGIYDNHYHHKHPLRVWNHAYGQKEWESCCSYKKPHPCRYCVDDNSQSKLAVHIPREEYMSSQEWLAKYGLKSRKLDFFDVLSGVCFRHCDGVVDVLEPPPVDKLDFMEQQNATLHQKLINAKYCDKFAHVKWKDGSLVHVQMSSDVHRLYSERMKLCLLAITRRIEWLRQGSRELFGTIMEDQVYILIDISASMEPHISFVKDKLYTLIQEQLRHKSKINFVAFNTKALPWRDRLVDVTEANLKSAWQWLEGLTCQGSTNTLSALQFAI----KDRN---CQGIYLLTDGRPDQPTKTVLSQIRLQYR---LPIHTISFNCADLEANTF--LC------------ELARETGGRFHYFNEISGGADCTNENELEAWESEDIKLLKSE 2294
SE WL LK L + L + G LE N N PK HF + + + L + ++LYQQR+ WL+ S++ FG+I+ V ++I + + +F + ++EQ+ K ++ L + + VS L W + S+NL++AL + +KE +L +I D E L + ++Q + +++ +Y C D + LK L GG +H Y +P++ L T D V + E +A+ L++Q+++L H +P + + E K P ++ L + P + S+ EWL GLK++KL + VL+ F + V +L+ + AT+H+K + +W DG++ ++ + V Y +++ + R++WL SR ++GT+ + +V IL+D+S + +I ++ L L++EQL +K N +AF + WR +V V+ NL+ AW+W GL CQGS N L AL+ AI KD+N QGIYL T G PDQ + + + Y L ++ F + + +T C E+ + GRFH+F E +ES+DI + SE
Sbjct: 63 SEDWLAMHSLKFEKLTLADLISQ-GTVELEDCN-------------NAVPKVHF-----------TTQTIHHFKSRLSDTIELYQQRMRWLTENSKKAFGLIKGSRVGLLIDSSQVSSGSQTKEFQNDLTGLIDEQLSLKEKLYVLSFGVTINPLWPDPMEVSTSTLQELKLW---VKTLQPEGSSNLLQALKKVFAHKELNSLVIILRS-CPDQPSEFLSDFIQQSTLGRSVFIHVTTYKCDDHVPSAVLKNLTDALGGYYHCY-----------------SPESELY--------------TSRDVVELQVETHKAQGLLSQVQALC---------------HNNPCEELSCMIKEISIEIA---KGPFTSLLPKPPKHEAPLTIKFPDLDKTSA-EWLKINGLKAKKLSLYQVLAPNAFNPVEEFVPILQ----------KTVAATIHEKAM--------VQFEWHDGTVKNIHVDPPVLFEYQKQLGKAVQIYEHRLQWLSLTSRRIWGTVCQRRVVILLDVSVTNSMYIIHIQHSLRLLLEEQLSNKDYFNIIAFGSTIESWRPEMVAVSHDNLQRAWRWALGLQCQGSRNVLGALRKAIEVDFKDKNKHESQGIYLFTGGIPDQDVHILSAYVAEAYGGCDLQLNVCLFYVGEPQMDTTPPACYASRTDTATAYKEITQAARGRFHWFGETG------------IYESDDINAIVSE 676 HSP 2 Score: 161.384 bits (407), Expect = 2.649e-38 Identity = 115/349 (32.95%), Postives = 175/349 (50.14%), Query Frame = 3
Query: 1353 AVHIPREEYM-SSQEWLAKYGLKSRKLDFFDVLSGVCFRHCDGVVDVLEPPPVDKLDFMEQQNATLHQKLINAKYCDKFAHVKWKDGSLVHVQMSSDVHRLYSERMKLCLLAITRRIEWLRQGSRELFGTIMEDQVYILIDISASMEPHISFVKDKLYTLIQEQLR-HKSKINFVAFNTKALPWRDRLVDVTEANLKSAWQWLEGLTCQGSTNTLSALQFAIKDRNCQGIYLLTDGRPDQPTKTVLSQIRL---QYRLPIHTISFNCADLEANTFLCELARETGGRFH------YFNEISG----GADCTNENELEAWESEDIKLLKSEYRLGFDSLEKVTKLRDECHK 2354
++ +PR++ + SSQEW A LK KL+ L C R+ V P + A++C F ++ +G + H+Q + Y M+ +R+ WL GSR LFGTI+E V IL+D S SM PH+ ++K +L LI EQLR H ++ N ++F W+D LV+ TEA A QW+ L QGST+ L+AL A ++ QG+YLLTDG+PD +L+ ++ + + +HTIS AD A FL ELA +GGR+H + I G G + +L +E +D++LL E+ + L++ R + K
Sbjct: 814 SIQLPRKDTVCSSQEWTATCRLKRLKLELSKCLGPNC-RYQKSV----RGPAL-------------------AEHCTLFPSIEI-NGVVRHIQWTLWEMETYITCMEKVTRCYVQRLHWLLSGSRRLFGTILERNVCILLDTSGSMGPHLQWIKTELVLLIWEQLRKHCARFNLLSFAEDLQLWQDTLVESTEAACHKAMQWVAHLQAQGSTSVLAALTKAFSFQDVQGLYLLTDGKPDTSCSLILNTVQSFQKERGVKVHTISLTSADRTATEFLRELASLSGGRYHCPVSDKALSGIQGLLTRGFIKERDPKLPLFEGDDLRLLAEEFTRARNLLKQAQVFRSQLLK 1137 HSP 3 Score: 77.0258 bits (188), Expect = 1.843e-12 Identity = 86/329 (26.14%), Postives = 136/329 (41.34%), Query Frame = 3
Query: 1386 SQEWLAKYGLKSRKLDFFDVLS--GVCFRHCDGVVDVLEPPPVDKLDFMEQQNATLHQKLINAKYCDKFAHVKWKDGSLVHVQMSSDVHRLYSERMKLCLLAITRRIEWLRQGSRELFGTIMEDQVYILIDIS-ASMEPHISFVKDKLYTLIQEQLRHKSKINFVAFNTKALP-WRDRLVDVTEANLKSAWQWLEGLTCQGSTNTLSALQFAIKDRNCQGIYLLTDGRPDQPTKTV---LSQIRLQYRLPIHTISFNCADLEANTFLCELARETGGRFHYFNEISGGADCTNENELEAWESEDIKLLKSEYRLGFDSLEKVTKLRDECH 2351
S++WLA + LK KL D++S V C+ V K+ F Q T+H H K + SD LY +RM+ WL + S++ FG I +V +LID S S ++ L LI EQL K K+ ++F P W D + +V+ + L+ W++ L +GS+N L AL+ + + ++ PDQP++ + + Q L + IH ++ C D + L L GG +H ++ E E + S D+ L+ E L +V L CH
Sbjct: 63 SEDWLAMHSLKFEKLTLADLISQGTVELEDCNNAVP--------KVHFTTQ---TIH-------------HFKSR---------LSDTIELYQQRMR-----------WLTENSKKAFGLIKGSRVGLLIDSSQVSSGSQTKEFQNDLTGLIDEQLSLKEKLYVLSFGVTINPLWPDPM-EVSTSTLQELKLWVKTLQPEGSSNLLQALKKVFAHKELNSLVIILRSCPDQPSEFLSDFIQQSTLGRSVFIHVTTYKCDDHVPSAVLKNLTDALGGYYHCYSP-----------ESELYTSRDVVELQVETHKAQGLLSQVQAL---CH 332 HSP 4 Score: 70.8626 bits (172), Expect = 1.269e-10 Identity = 63/227 (27.75%), Postives = 101/227 (44.49%), Query Frame = 3
Query: 174 PTKVWNPDAKLQVSSEQWLNKFGLKASNLDSSSLYPRLGFARLEGFNDVLKKPIHSRYGDNLFPKHFREDGLTFNVVAKKEKLLQVQQELENAVQLYQQRLEWLSSESRRLFGVIEEHCVTXXXXXXXXXXRDFDQFICAIERFLNEQIRCIAKFNLIRVQENKCQLSNNLLPVSKDNLANGIDWLWQIDRTSATNSANLVEALIRA-------SNNKENEALYLIT 833
P + PD L +S +WL GLKA L + F +E F +L+K + + + + DG N+ L + Q++L AVQ+Y+ RL+WLS SRR++G + + V I++D+ N ++ L EQ+ FN+I ++ VS DNL W W + S N++ AL +A N E++ +YL T
Sbjct: 368 PLTIKFPD--LDKTSAEWLKINGLKAKKLSLYQVLAPNAFNPVEEFVPILQKTVAATIHEKAMVQFEWHDGTVKNIHVDPPVLFEYQKQLGKAVQIYEHRLQWLSLTSRRIWGTVCQRRVVILLDVSVTNSMYIIHIQHSLRLLLEEQLSNKDYFNIIAFGSTIESWRPEMVAVSHDNLQRA--WRWALG-LQCQGSRNVLGALRKAIEVDFKDKNKHESQGIYLFT 589 HSP 5 Score: 63.1586 bits (152), Expect = 3.172e-8 Identity = 53/188 (28.19%), Postives = 90/188 (47.87%), Query Frame = 3
Query: 441 LENAVQLYQQRLEWLSSESRRLFGVIEEHCVTXXXXXXXXXXRDFDQFICAIERFLNEQIR--CIAKFNLIRVQENKCQLSNNLLPVSKDNLANGIDWLWQIDRTSATNSANLVEALIRASNNKENEALYLITEDLSSDGSREVLREKV----KQLKIPLNIISYNCKDPEFISYLKCLVLMTGGRFH 986
+E + Y QRL WL S SRRLFG I E V I++D + + EQ+R C A+FNL+ E+ + L+ ++ + W+ + A S +++ AL +A + ++ + LYL+T D D S ++ V K+ + ++ IS D +L+ L ++GGR+H
Sbjct: 894 MEKVTRCYVQRLHWLLSGSRRLFGTILERNVCILLDTSGSMGPHLQWIKTELVLLIWEQLRKHC-ARFNLLSFAEDLQLWQDTLVESTEAACHKAMQWVAHLQ---AQGSTSVLAALTKAFSFQDVQGLYLLT-DGKPDTSCSLILNTVQSFQKERGVKVHTISLTSADRTATEFLRELASLSGGRYH 1076
BLAST of von Willebrand factor A domain containing 3B vs. UniProt/SwissProt
Match: sp|A1A5Q7|VWA3A_RAT (von Willebrand factor A domain-containing protein 3A OS=Rattus norvegicus OX=10116 GN=Vwa3a PE=2 SV=1) HSP 1 Score: 163.696 bits (413), Expect = 1.105e-39 Identity = 173/698 (24.79%), Postives = 291/698 (41.69%), Query Frame = 3
Query: 216 SEQWLNKFGLKASNLDSSSLYPRLGFARLEGFNDVLKKPIHSRYGDNLFPKHFREDGLTFNVVAKKEKLLQVQQELENAVQLYQQRLEWLSSESRRLFGVIEEHCVTXXXXXXXXXXR-DFDQFICAIERFLNEQIRCIAKFNLIRVQENKCQLSNNLLPVSKDNLANGIDWLWQIDRTSATNSANLVEALIRASNNKENEALYLITEDLSSDGSREVLREKVKQLKIP----LNIISYNCKDPEFISYLKCLVLMTGGRFHSYLFNLEVDAYESSPLD---SENPKANLLLKKKVYGGSIGGIGTRNDCVAVFSEIEEAKALINQIKSLINQIPEKKGIYDNHYHHKHPLRVWNHAYGQKEWESCCSYKKPHPCRYCVDDNSQSKLAVHIPREEYMSSQEWLAKYGLKSRKLDFFDVLSGVCFRHCDGVVDVLEPPPVDKLDFMEQQNATLHQKLINAKYCDKFAHVKWKDGSLVHVQMSSDVHRLYSERMKLCLLAITRRIEWLRQGSRELFGTIMEDQVYILIDISASMEPHISFVKDKLYTLIQEQLRHKSKINFVAFNTKALPWRDRLVDVTEANLKSAWQWLEGLTCQGSTNTLSALQFAI----KDRN---CQGIYLLTDGRPDQPTKTV---LSQIRLQYRLPIHTISFNCADLEANTF--LC------------ELARETGGRFHYFNE 2213
SE WL LK L + L + G LE N+ + K HF + + L + ++LYQQR+ WL+ S++ FG+I+ V ++ID + ++F + ++EQ+ K ++ L + + VS L W + S+NL++AL + KE +L I D E L + ++Q + ++I++Y C D + LK L GG +H Y + E + Y S +D +E KA L + + + N C EE +I +I + I + P + P P ++ ++ L + P + S+ EWL GLK++KL + VL+ F + V +L+ + AT+H+K + +W DG++ ++ + V Y +++ + +R++WL SR +GT+ + +V IL+D+S + I ++ L L++EQL +K N +AF + WR +V V+ NL+ AW+W GL CQGS N L AL+ AI KD+ QGIYL T G PDQ + +++ L ++ F + + NT C E+ + GRFH+F E
Sbjct: 63 SEDWLAMHSLKFEKLTLADLISQ-GTVELEDQNNAVPK------------VHF-----------TTQTIYHFTSRLSDTIELYQQRMRWLTENSKKAFGLIKGSRVGLLIDSSQVSSGPQTEEFQNDLTSLIDEQLSLKEKLYVLTFGGTTNFLWPDPVEVSASTLQELKLW---VKTLQPEGSSNLLQALKKVLARKELNSLVAILRS-CPDQPSEFLSDFIQQSTLGRSLFIHIVTYKCDDHVPSAILKNLTDALGGHYHCY--SPESELYTSRDVDELLAETHKAQGLFSQ------LQALCHNNPC-------EELSCMIEEISTEIAKGPFTSLL-------------------------------PKPPKH------EAPLTIKFPDLDKTSA-EWLKINGLKAKKLGLYQVLAPNAFNPVEEFVPILQ----------KTVGATIHEKAM--------VQFEWHDGTVKNIHVDPPVLFEYQKQLGKAVQIYEKRLQWLSLTSRRFWGTVCQRRVVILLDVSVTNSMFIIHIQHSLRLLLEEQLSNKDYFNIIAFGSTVESWRPEMVAVSHDNLQRAWRWALGLQCQGSRNVLGALRKAIEVDFKDKTKHESQGIYLFTGGVPDQDVHILSAYVAEACGGCDLQLNVCLFYVGEPQMNTTPPACYASRTDTAAAYKEVTQAACGRFHWFGE 661 HSP 2 Score: 83.1889 bits (204), Expect = 1.872e-14 Identity = 97/378 (25.66%), Postives = 155/378 (41.01%), Query Frame = 3
Query: 1386 SQEWLAKYGLKSRKLDFFDVLSGVCFRHCDGVVDVLEPPPVDKLDFMEQQNATLHQKLINAKYCDKFAHVKWKDGSLVHVQMS-SDVHRLYSERMKLCLLAITRRIEWLRQGSRELFGTIMEDQVYILIDIS-ASMEPHISFVKDKLYTLIQEQLRHKSKINFVAFN-TKALPWRDRLVDVTEANLKSAWQWLEGLTCQGSTNTLSALQFAIKDRNCQGIYLLTDGRPDQPTKTV---LSQIRLQYRLPIHTISFNCADLEANTFLCELARETGGRFHYFNEISGGADCTNENELEAWESEDIKLLKSEYRLGFDSLEKVTKLRDECHKLAWKSEVVRKKEQKSTRKTMAPGCNQNPYFSQISPSRPKCEN-REIKYP 2498
S++WLA + LK KL D++S G V+ +E QN + V + ++ H SD LY +RM+ WL + S++ FG I +V +LID S S P ++ L +LI EQL K K+ + F T W D V+V+ + L+ W++ L +GS+N L AL+ + + + + PDQP++ + + Q L L IH +++ C D + L L GG +H ++ E E + S D+ L +E ++ L CH + E+ E+ ST P F+ + P PK E IK+P
Sbjct: 63 SEDWLAMHSLKFEKLTLADLIS-------QGTVE------------LEDQN-------------NAVPKVHFTTQTIYHFTSRLSDTIELYQQRMR-----------WLTENSKKAFGLIKGSRVGLLIDSSQVSSGPQTEEFQNDLTSLIDEQLSLKEKLYVLTFGGTTNFLWPDP-VEVSASTLQELKLWVKTLQPEGSSNLLQALKKVLARKELNSLVAILRSCPDQPSEFLSDFIQQSTLGRSLFIHIVTYKCDDHVPSAILKNLTDALGGHYHCYSP-----------ESELYTSRDVDELLAETHKAQGLFSQLQAL---CHNNPCE-ELSCMIEEISTEIAKGP-------FTSLLPKPPKHEAPLTIKFP 374 HSP 3 Score: 68.1662 bits (165), Expect = 7.933e-10 Identity = 62/227 (27.31%), Postives = 100/227 (44.05%), Query Frame = 3
Query: 174 PTKVWNPDAKLQVSSEQWLNKFGLKASNLDSSSLYPRLGFARLEGFNDVLKKPIHSRYGDNLFPKHFREDGLTFNVVAKKEKLLQVQQELENAVQLYQQRLEWLSSESRRLFGVIEEHCVTXXXXXXXXXXRDFDQFICAIERFLNEQIRCIAKFNLIRVQENKCQLSNNLLPVSKDNLANGIDWLWQIDRTSATNSANLVEALIRA-------SNNKENEALYLIT 833
P + PD L +S +WL GLKA L + F +E F +L+K + + + + DG N+ L + Q++L AVQ+Y++RL+WLS SRR +G + + V I++D+ N ++ L EQ+ FN+I ++ VS DNL W W + S N++ AL +A E++ +YL T
Sbjct: 368 PLTIKFPD--LDKTSAEWLKINGLKAKKLGLYQVLAPNAFNPVEEFVPILQKTVGATIHEKAMVQFEWHDGTVKNIHVDPPVLFEYQKQLGKAVQIYEKRLQWLSLTSRRFWGTVCQRRVVILLDVSVTNSMFIIHIQHSLRLLLEEQLSNKDYFNIIAFGSTVESWRPEMVAVSHDNLQRA--WRWALG-LQCQGSRNVLGALRKAIEVDFKDKTKHESQGIYLFT 589
BLAST of von Willebrand factor A domain containing 3B vs. UniProt/SwissProt
Match: sp|Q29052|ITIH1_PIG (Inter-alpha-trypsin inhibitor heavy chain H1 OS=Sus scrofa OX=9823 GN=ITIH1 PE=2 SV=1) HSP 1 Score: 66.2402 bits (160), Expect = 3.794e-9 Identity = 78/293 (26.62%), Postives = 125/293 (42.66%), Query Frame = 3
Query: 1422 RKLDFFDVLSGV----CFRHCDGVVDVLEPPPVDKLD----FMEQQNATLHQKLINAKYCDKFAHVKWKD--------GSLVHVQMSSDVHRLYS-ERMKLCLLAITRRIEWLRQGSRELFGTIMEDQVYILIDISASMEPH-ISFVKDKLYTLIQEQLRHKSKINFVAFNTKALPWRDRLVDVTEANLKSAWQWLEGLTCQGSTNTLSALQFAIKDRN-CQG-----------IYLLTDGRPDQPT---KTVLSQIR--LQYRLPIHTISFNCADLEANTFLCELARETGGR 2195
RKL +D++ V +H + VD+ EP + KLD F+ ++ A +LI + K HV ++ + ++ D Y R KLC L + + L T + V +IDIS+SME + K+ L ++ + L+ + V F + WR LV + ANL +A ++ + GSTN L I+ N QG + +LTDG P + +L +R ++ R P++ + F D+E N FL A E GR
Sbjct: 162 RKLTQYDIVIKVKPKQLVQHFEIDVDIFEPQGISKLDAQASFLSKEAAA---QLIKKSFSGKKGHVLFRPTVGQQQSCSTCSTTLLNGDFKVTYDVNREKLCDLLVANNYFAHFFAPQNL--TKLNKNVVFVIDISSSMEGQKVKQTKEALLKILSD-LKPGDYFDLVLFGSAVQSWRGSLVQASTANLDAARSYVRQFSLAGSTNLNGGLLRGIEILNKAQGSLPEFSNRASILIMLTDGEPTEGVTDRSQILKNVRDAIRGRFPLYNLGFG-HDVEWN-FLEVRALENNGR 446
BLAST of von Willebrand factor A domain containing 3B vs. TrEMBL
Match: A0A267H1B9 (VWFA domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig024046g1 PE=4 SV=1) HSP 1 Score: 878.241 bits (2268), Expect = 0.000e+0 Identity = 479/1063 (45.06%), Postives = 665/1063 (62.56%), Query Frame = 3
Query: 174 PTKVWNPDAKLQVSSEQWLNKFGLKASNLDSSSLYPRLGFARLEGFNDVLKKPIHSRYGDNLFPKHFREDGLTFNVVAKKEKLLQVQQELENAVQLYQQRLEWLSSESRRLFGVIEEHCVTXXXXXXXXXXRDFDQFICAIERFLNEQIRCIAKFNLIRVQENKCQLSNNLLPVSKDNLANGIDWLWQIDRTSATNSANLVEALIRASNNKENEALYLITEDLSSDGSREVLREKVKQL-KIPLNIISYNCKDPEFISYLKCLVLMTGGRFHSYLFNLEVDAYESSPLDSENPKANLLLKKKVYGGSIGGIGTRNDCVAVFSEIEEAKALINQIKSLINQIPEKKGIYDNHYHHKHPLRVWNHAYGQKEWESCCSYKKPHPCRYCVDDNSQSKLAVHIPREEYMSSQEWLAKYGLKSRKLDFFDVLSGVCFRHCDGVVDVLEPPPVDKLDFMEQQNATLHQKLINAKYCDKFAHVKWKDGSLVHVQMSSDVHRLYSERMKLCLLAITRRIEWLRQGSRELFGTIMEDQVYILIDISASMEPHISFVKDKLYTLIQEQLRHKSKINFVAFNTKALPWRDRLVDVTEANLKSAWQWLEGLTCQGSTNTLSALQFAIKDRNCQGIYLLTDGRPDQPTKTVLSQIRLQYRLPIHTISFNCADLEANTFLCELARETGGRFHYFNEISGGADCTNENELEAWESEDIKLLKSEYRLGFDSLEKVTKLRDECHKLAWKSEVVRKKEQKSTRKTMAPGCNQNPYFSQISPSRPKCENREIKYPRPIKAKNTFRKQQKEQENDPIWSGTIKLLNLDSTTVASQSDAYQSFLEALSSRDENEQEWVIDETQEIIDRQTERYKKILEDEYNEAMSXXXXXXXXXXXXXXXXXXXQWLHIYGLVPQHMTILDALAPTIVKVRPKYVPIIDKYVMSKVFEEILPISHVVTEGSPKRGYKPVVRLVNPLAVDLKAYQEKLENLMNKYRKKLRKLIQIHIGDSTLNAFDEMLVKYPLGN-----DDVKRWVMKAFRDANWPMGEEELEMFMNEIYIGQKYFIQAGDLLRI-RGKTGP 3341
P + W D + + S+ WL K+GLK + LD+ S+ +LGF L F+ VLKKPI SRYGDNLF + R+DG +N+ A KEKL QV+Q L +AV++Y++R+EWL+SESRR+FGVI EH V II+DIKN + R FD ++CA ER L EQI AKFNLIR + S PV+++ + N IDWLWQ+DR + T+ + VE +IRA+ + + EA+YL TE SSD SRE+L +KVK ++P ++++YNC+ + + +L+ + +TGGRFH Y +EVD++E PLD E KAN++LK+K+YGG G G R D VF E+EEA+ L+ Q++ ++ P+ + + K P + + H +EEYM S EWL ++G+ ++KLDFFD+L+GV FRHCDGVV+V+ P + + E+ A + KLINA+YCD+FAHV KDG+++HVQ++ ++HR+Y ERM +CL +I RRI+WLR+GSRELFGTI+EDQVY LID SASMEP I FVKDKLY LIQEQLRHK ++NFVAFNTKA PW+DRLV+VTE +L++AW W++ L+C G+TNTL+AL+FA+ DR +YLLTDGRPDQP KTVLSQ +L RLPIHTISFNC D EAN FL +LAR+TG RFH F +D N+ E+WESEDI+LL+ EY LG L++V LRDECH+LAWK E + + ++ P C P Q +P+R ++ P A+ T K+ + P Q L + R E+ WV+ ET+E++ RQ ER E ++ K+ ++++++ KQWL +GL Q MTILDAL+PTIV+ RPKYVPI+++ V+++VF++I+PI++ SP+ + ++LVNP AVDLKAY+ KL L+ KY K+L LI + T DE L K G D K +A A WP+ E ++ + E+ + Y QA DL R+ GK P
Sbjct: 74 PGERWEIDVRDLIPSDSWLAKYGLKKNRLDAHSIAAQLGFQHLTEFDSVLKKPISSRYGDNLFQRLLRDDGKVYNITAGKEKLKQVEQRLLHAVRMYRRRMEWLTSESRRIFGVIYEHSVCIILDIKNMSPRAFDTYLCAAERVLKEQIIHKAKFNLIRCADEVQYFSTRCQPVTRETVQNAIDWLWQLDRLAPTSPTDTVEGVIRAAADPDIEAIYLFTEGSSSDASREILIDKVKSCSEVPFHVVAYNCQSSDTLRFLRGVCELTGGRFHCYSITMEVDSFEGLPLDPETNKANIVLKRKLYGGVPAGGGIRADVFKVFEELEEARNLLAQVQHVLANTPDPQAL------------------------------KESPV-------ERDTVTAHERKEEYMKSSEWLQRFGIVAKKLDFFDILAGVSFRHCDGVVNVMRAPDGNP-EAREKAGALIQPKLINARYCDRFAHVLGKDGTVLHVQVTPELHRIYEERMNVCLESIQRRIDWLREGSRELFGTIVEDQVYFLIDTSASMEPSIGFVKDKLYILIQEQLRHKLRVNFVAFNTKAYPWKDRLVEVTEQSLQTAWNWIKALSCFGTTNTLAALKFALSDRQTHAVYLLTDGRPDQPFKTVLSQAQLHNRLPIHTISFNCRDREANQFLFQLARDTGARFHIF------SDQANDGGPESWESEDIRLLREEYELGKGYLDRVAALRDECHRLAWKRETAADSPEGAVARS-TPRCLDRP---QSAPNR-------VQKKTPRSARQTTGKRGGAKVQPPA----------------------QPLLAINADRSED---WVLPETREMLARQRERDAL----RQQEHQRQQHRQRNKEMLREENMSSKQWLKRHGLAAQRMTILDALSPTIVQHRPKYVPILNRMVLARVFDDIMPIAY----ASPRNRHS--IQLVNPAAVDLKAYKTKLRKLVEKYNKRLDSLI---LSSLTKEQLDE-LSKQCDGEERPDFDSNKAAFYQALEQARWPVSESDVFLLEKEVEKARLYLQQADDLQRVSSGKETP 1042
BLAST of von Willebrand factor A domain containing 3B vs. TrEMBL
Match: A0A1S3J9G4 (von Willebrand factor A domain-containing protein 3B OS=Lingula unguis OX=7574 GN=LOC106171300 PE=4 SV=1) HSP 1 Score: 857.055 bits (2213), Expect = 0.000e+0 Identity = 505/1330 (37.97%), Postives = 748/1330 (56.24%), Query Frame = 3
Query: 132 TDAVIVPEIDMKLYPTKVWNPDAKLQVSSEQWLNKFGLKASNLDSSSLYPRLGFARLEGFNDVLKKPIHSRYGDNLFPKHFREDGLTFNVVAKKEKLLQVQQELENAVQLYQQRLEWLSSESRRLFGVIEEHCVTXXXXXXXXXXRDFDQFICAIERFLNEQIRCIAKFNLIRVQENKCQLSNNLLPVSKDNLANGIDWLWQIDRTSATNSANLVEALIRASNNKENEALYLITEDLSSDGSREVLREKVKQLKIPLNIISYNCKDPEFISYLKCLVLMTGGRFHSYLFNLEVDAYESSPLDSENPKANLLLKKKVYGGSIGGIGTRNDCVAVFSEIEEAKALINQIKSLINQIPEKKGIYDNHYHHKHPLRVWNHAYGQKEWESCCSY--KKPHPCRYCVDDNSQSKLAVHI-------PREEYMSSQEWLAKYGLKSRKLDFFDVLSGVCFRHCDGVVDVLEPPPVDKLDFMEQQNATLHQKLINAKYCDKFAHVKWKDGSLVHVQMSSDVHRLYSERMKLCLLAITRRIEWLRQGSRELFGTIMEDQVYILIDISASMEPHISFVKDKLYTLIQEQLRHKSKINFVAFNTKALPWRDRLVDVTEANLKSAWQWLEGLTCQGSTNTLSALQFAIKDRNCQGIYLLTDGRPDQPTKTVLSQIRLQYRLPIHTISFNCADLEANTFLCELARETGGRFHYFNEISGGADCTNENELEAWESEDIKLLKSEYRLGFDSLEKVTKLRDECHKLAWKSEVVRK-----KEQKSTRKTMAPGCNQNPYFSQISPSRPKCEN--REIKYP--------------RPIKAKNTFRKQQKEQENDPIWSGTIKLLNLDSTTVASQSDAYQSFLEALSSRDE-NEQEWVIDETQEIIDRQTERYKKILEDEYNEAMSXXXXXXXXXXXXXXXXXXXQWLHIYGLVPQHMTILDALAPTIVKVRPKYVPIIDKYVMSKVFEEILPISHVVTEGSPKRGYKPVVRLVNPLAVDLKAYQEKLENLMNKYRKKLRKLIQIHIGDSTLNAFDEMLVKYPLGNDDVKRWVMKAFRDANWPMGEEELEMFMNEIYIGQKYFIQAGDLLRIRGKTG-------------------------------------PGKGGKDETP--------EFEPFDGELQN--------------TNEPFSKVLLAAMKGATILAPGPEDGYYYDAQIINWPNCDFVDVQF-----NMFAGITSVPVPDCVILPEKYARITAGMTALIKVYNMDNDRTFYLPGIITSSKIVHPGLNEERYH-VTLYNGLESTVRPDEVVAISKENYDRIIKNIED 3833
TD + PEI K P K W D + +SS++WL +GLK + LD+ S+ P +GF ++ ++ LKKPI SRYG+ +F K+ R DG TFN+ KE+L Q++ L AV LY++RLEWL++ESRR+FGVIEEHC+ I++DIKN + + FDQ+ A ER L EQ+ IAKFNLIR E+ L+PV++++L DWLW +DR +A ++ EA+++A ++ EA+YL TE +SDGSRE+LR K+ +PL++ SYN E + +LK L +TGG+FH+Y +E+DAYE P+D +AN++LK+K +GG G G R D + VF E+EEA+ ++QI++LI +P++K I S Y +KP R +++ + AV E+YMSS+EWL GLK++KL F+D+L GV F+HCDGVVD+ + P D DF Q +A + KLINA+YCDKFAHVKWK+G +VHVQ++ +VHR Y R+ + L ++ +RI+WL+QGSRELFGT++EDQ+YILID S SM P I FVKDKL+ L+QEQLRHK K N V+FN+K PW+DR V+V E NL++AW W++ L C GSTNTL+ALQFA+ D Q +YLLTDGRPDQP +++L+Q++LQ+ +P+HTISFNC+D EAN FLC+LA++TGGR+HY++E G D N + WESEDI+LL+ E LG ++L+K+ LRDEC LAWK E VR K + R + P N + + +RPK R + RP A R + + P + + L T S L LSS + EW++ ET+E+ D+Q +R LE+E E + KK +++ K WL GL+ + +TILDALAPT+++ K++P++D Y +SKVF++ +P +HV S +R + LVNP +VDLKAY+ K+ + KY+K+L ++ + + F P+ +D K +++A WP+ E ++ EI G+KY +Q+ L + K G KG + ++P ++E +Q+ T KVL ++G +++A DG YY +I + V+ + A +P V P + G L +V N + +R Y+PGI+ + + +++ R+ V LY G E+T + ++ ISK Y ++ I +
Sbjct: 43 TDESVNPEISTKKAPPKEWELDVRALISSKKWLMNYGLKRNRLDTHSIMPIIGFKHMDDYDYALKKPISSRYGEGMFSKYHRTDGTTFNLTCNKEQLKQIESRLIQAVLLYKRRLEWLTTESRRIFGVIEEHCICIVLDIKNLSPQQFDQYRSAFERVLVEQVAQIAKFNLIRSAEDMVMFKPELVPVTQESLQEAKDWLWNLDRCAAFSNTATCEAVLKAMTDRNVEAVYLFTEGSASDGSRELLRTKLHGGPLPLHVASYNATSVETVGFLKQLCEVTGGKFHAYGVIMEMDAYEGVPVDPNTNRANIVLKRKTFGGVPQGAGVREDVIKVFEELEEARNTLSQIQALIEDMPDQKMI--------------ERTKSDTALSSRGGYVPRKPLMTRQSSMTDTRGRKAVDYPPPPPKEKSEQYMSSKEWLEMNGLKAKKLGFYDILGGVAFKHCDGVVDLNQKP--DYHDF--QTDARVQPKLINARYCDKFAHVKWKNGKVVHVQVTPEVHRSYERRVNVVLDSLQQRIDWLQQGSRELFGTVIEDQIYILIDTSGSMAPSIQFVKDKLFVLMQEQLRHKQKFNLVSFNSKISPWKDRCVEVNEKNLQAAWTWIKNLECVGSTNTLAALQFALADHATQAVYLLTDGRPDQPPRSILAQVQLQHAVPLHTISFNCSDKEANQFLCQLAKDTGGRYHYYSE--HGQDPDNPS---PWESEDIRLLREELELGKENLQKIADLRDECAALAWKKENVRSCSRNHKLSSTDRVSTVPALNPSELYRSPGSNRPKSATGYRSTSHSTPTPPPRPSSATGYRPRSAGAGGRSARHRTVSCPRPASARRPLVAGHTRT--------SLLRTLSSSARFSSNEWLLPETRELFDKQAKR----LEEEV-EGKVVIEKKRKKRVSNPNNMSAKMWLKHNGLLAKKLTILDALAPTMIEQNAKHIPVLDAYALSKVFDDSMPFAHV----SNRRH----IHLVNPDSVDLKAYENKVSAAVEKYKKRLDAMVWKALPATEREQFGST---EPISFEDNKLALLQALERCGWPVKESDILAMEGEISQGRKYLLQSEGLRKASEKHGHIGCSEKSESENDDASSVASSPRSMSSKGSKSSKGSRSPKGSQTKSPRGSVASSKDYEGLGEAIQSKSVKEKDKVLSSPATQRKVRKVL-DTLRGQSVIARLETDGLYYPGMVIKCTDSRHALVELHDNGKHRIATRFIIPTGGAVSRPP----LREGDYVLARVKNSETERECYVPGIVQVTPL--RSMDQARFFTVQLYTGQEATCMRNYLIKISKTRYAFAVRYISE 1318
BLAST of von Willebrand factor A domain containing 3B vs. TrEMBL
Match: A0A1I8I366 (Uncharacterized protein OS=Macrostomum lignano OX=282301 PE=4 SV=1) HSP 1 Score: 849.736 bits (2194), Expect = 0.000e+0 Identity = 485/1131 (42.88%), Postives = 674/1131 (59.59%), Query Frame = 3
Query: 39 YRMYEMKNTPNVQISPTFDLPK-----------KNIVSTIKRTDAVIVPE---IDMKLYPTKVWNPDAKLQVSSEQWLNKFGLKASNLDSSSLYPRLGFARLEGFNDVLKKPIHSRYGDNLFPKHFREDGLTFNVVAKKEKLLQVQQELENAVQLYQQRLEWLSSESRRLFGVIEEHCVTXXXXXXXXXXRDFDQFICAIERFLNEQIRCIAKFNLIRVQENKCQLSNNLLPVSKDNLANGIDWLWQIDRTSATNSANLVEALIRASNNKENEALYLITEDLSSDGSREVLREKVKQL-KIPLNIISYNCKDPEFISYLKCLVLMTGGRFHSYLFNLEVDAYESSPLDSENPKANLLLKKKVYGGSIGGIGTRNDCVAVFSEIEEAKALINQIKSLINQIPEKKGIYDNHYHHKHPLRVWNHAYGQKEWESCCSYKKPHPCRYCVDDNSQSKLAVHIPREEYMSSQEWLAKYGLKSRKLDFFDVLSGVCFRHCDGVVDVLEPPPVDKLDFMEQQNATLHQKLINAKYCDKFAHVKWKDGSLVHVQMSSDVHRLYSERMKLCLLAITRRIEWLRQGSRELFGTIMEDQVYILIDISASMEPHISFVKDKLYTLIQEQLRHKSKINFVAFNTKALPWRDRLVDVTEANLKSAWQWLEGLTCQGSTNTLSALQFAIKDRNCQGIYLLTDGRPDQPTKTVLSQIRLQYRLPIHTISFNCADLEANTFLCELARETGGRFHYFNEISGGADCTNENELEAWESEDIKLLKSEYRLGFDSLEKVTKLRDECHKLAWKSEVVRKKEQKSTRKTMAPGCNQNPYFSQISPSRPKCENREIKYPRPIKAKNTFRKQQKEQENDPIWSGTIKLLNLDSTTVASQSDAYQSFLEALSSRDENEQEWVIDETQEIIDRQTERYKKILEDEYNEAMSXXXXXXXXXXXXXXXXXXXQWLHIYGLVPQHMTILDALAPTIVKVRPKYVPIIDKYVMSKVFEEILPISHVVTEGSPKRGYKPVVRLVNPLAVDLKAYQEKLENLMNKYRKKLRKLIQIHIGDSTLNAFDEMLVKYPLGN-----DDVKRWVMKAFRDANWPMGEEELEMFMNEIYIGQKYFIQAGDLLRIRGKTGPGKGGKDETPE 3371
+ + E TP +P F + K + +VS +D V E +D+ P + W D + + S+ WL K+GLK + LD+ S+ +LGF L F+ VLKKPI SRYGDNLF + R+DG +N+ A KEKL QV+Q L +AV++Y++R+EWL+SESRR+FGVI EH V II+DIKN + R FD ++CA ER L EQI AKFNLIR + S PV+++ + N IDWLWQ+DR + T+ + VE +IRA+ + + EA+YL TE SSD SRE+L +KVK ++P ++++YNC+ + + +L+ + +TGGRFH Y +EVD++E PLD E KAN++LK+K+YGG G G R D VF E+EEA+ L+ Q++ ++ P D + P+ + + H +EEYM S EWL ++G+ ++KLDFFD+L+GV FRHCDGVV+V+ P + + E+ A + KLINA+YCD+FAHV KDG+++HVQ++ ++HR+Y ERM +CL +I RRI+WLR+GSRELFGTI+EDQVY LID SASMEP I FVKDKLY LIQEQLRHK ++NFVAFNTKA PW+DRLV+VTE +L++AW W ++FA+ DR +YLLTDGRPDQP KTVLSQ +L RLPIHTISFNC D EAN FL +LAR+TG RFH F+ D N+ E+WESEDI+LL+ EY LG L++V LRDECH+LAWK E + + ++ P C P Q +P+R ++ P A+ T K+ P Q L + R E+ WV+ ET+E++ RQ ER E ++ K+ ++++++ KQWL +GL Q MTILDAL+PTIV+ RPKYVPI+++ V+++VF++I+PI++ SP+ + ++LVNP AVDLKAY+ KL L+ KY K+L LI + T DE L K G D K +A A WP+ E ++ + E+ + Y QA DL R+ GK ETPE
Sbjct: 1251 WSLAEAVETPAGGTAPAFHVSKQQQQSQDGGSIREVVSGRGGSDIVQTSEKYNVDVP-KPGERWEIDVRDLIPSDSWLAKYGLKKNRLDAHSIAAQLGFQHLTEFDSVLKKPISSRYGDNLFQRLLRDDGKVYNITAGKEKLKQVEQRLLHAVRMYRRRMEWLTSESRRIFGVIYEHSVCIILDIKNMSPRAFDTYLCAAERVLKEQIIHKAKFNLIRCADEVQYFSTRCQPVTRETVQNAIDWLWQLDRLAPTSPTDTVEGVIRAAADPDIEAIYLFTEGSSSDASREILIDKVKSCSEVPFHVVAYNCQSSDTLRFLRGVCELTGGRFHCYSITMEVDSFEGLPLDPETNKANIVLKRKLYGGVPAGGGIRADVFKVFEELEEARNLLAQVQHVLANTP------DPQASKESPV-------------------------------ERDTVTAHERKEEYMKSSEWLQRFGIVAKKLDFFDILAGVSFRHCDGVVNVMRAPDGNP-EAREKAGALIQPKLINARYCDRFAHVLGKDGTVLHVQVTPELHRIYEERMNVCLESIQRRIDWLREGSRELFGTIVEDQVYFLIDTSASMEPSIGFVKDKLYILIQEQLRHKLRVNFVAFNTKAYPWKDRLVEVTEQSLQTAWNW---------------IKFALSDRQTHAVYLLTDGRPDQPFKTVLSQAQLHNRLPIHTISFNCRDREANQFLFQLARDTGARFHIFS------DQANDGGPESWESEDIRLLREEYELGKGYLDRVAALRDECHRLAWKRETAADSPEGAVARST-PRCLDRP---QSAPNR-------VQKKTPRSARQTTGKRGGAMVQPPA----------------------QPLLAINADRSED---WVLPETREMLARQRERDAL----RQQEHQRQQHRQRNKEMLREENMSSKQWLKRHGLAAQRMTILDALSPTIVQHRPKYVPILNRMVLARVFDDIMPIAYA----SPRNRHS--IQLVNPAAVDLKAYKAKLRKLVEKYNKRLDSLI---LSSLTKEQLDE-LSKQCDGEERPDFDSNKAAFYQALEQARWPVSESDVFLLEKEVEKARLYLQQADDLQRV-------SSGK-ETPE 2263
BLAST of von Willebrand factor A domain containing 3B vs. TrEMBL
Match: A0A1S3HNE2 (von Willebrand factor A domain-containing protein 3B OS=Lingula unguis OX=7574 GN=LOC106156712 PE=4 SV=1) HSP 1 Score: 818.92 bits (2114), Expect = 0.000e+0 Identity = 485/1301 (37.28%), Postives = 719/1301 (55.27%), Query Frame = 3
Query: 279 PRLGFARLEGFNDVLKKPIHSRYGDNLFPKHFREDGLTFNVVAKKEKLLQVQQELENAVQLYQQRLEWLSSESRRLFGVIEEHCVTXXXXXXXXXXRDFDQFICAIERFLNEQIRCIAKFNLIRVQENKCQLSNNLLPVSKDNLANGIDWLWQIDRTSATNSANLVEALIRASNNKENEALYLITEDLSSDGSREVLREKVKQLKIPLNIISYNCKDPEFISYLKCLVLMTGGRFHSYLFNLEVDAYESSPLDSENPKANLLLKKKVYGGSIGGIGTRNDCVAVFSEIEEAKALINQIKSLINQIPEKKGIYDNHYHHKHPLRVWNHAYGQKEWESCCSY--KKPHPCRYCVDDNSQSKLAVHI-------PREEYMSSQEWLAKYGLKSRKLDFFDVLSGVCFRHCDGVVDVLEPPPVDKLDFMEQQNATLHQKLINAKYCDKFAHVKWKDGSLVHVQMSSDVHRLYSERMKLCLLAITRRIEWLRQGSRELFGTIMEDQVYILIDISASMEPHISFVKDKLYTLIQEQLRHKSKINFVAFNTKALPWRDRLVDVTEANLKSAWQWLEGLTCQGSTNTLSALQFAIKDRNCQGIYLLTDGRPDQPTKTVLSQIRLQYRLPIHTISFNCADLEANTFLCELARETGGRFHYFNEISGGADCTNENELEAWESEDIKLLKSEYRLGFDSLEKVTKLRDECHKLAWKSEVVRK-----KEQKSTRKTMAPGCNQNPYFSQISPSRPK------------------------------------CENREIKYPRPIKAKNTFRKQQKEQENDPIWSGTIKLLNLDSTTVASQSDAYQSFLEALSSRDE-NEQEWVIDETQEIIDRQTERYKKILEDEYNEAMSXXXXXXXXXXXXXXXXXXXQWLHIYGLVPQHMTILDALAPTIVKVRPKYVPIIDKYVMSKVFEEILPISHVVTEGSPKRGYKPVVRLVNPLAVDLKAYQEKLENLMNKYRKKLRKLIQIHIGDSTLNAFDEMLVKYPLGNDDVKRWVMKAFRDANWPMGEEELEMFMNEIYIGQKYFIQAGDLLRIRGKTG-------------------------------------PGKGGKDETP--------EFEPFDGELQN--------------TNEPFSKVLLAAMKGATILAPGPEDGYYYDAQIINWPNCDFVDVQF-----NMFAGITSVPVPDCVILPEKYARITAGMTALIKVYNMDNDRTFYLPGIITSSKIVHPGLNEERYH-VTLYNGLESTVRPDEVVAISKENYDRIIKNIED 3833
P +GF ++ ++ LKKPI SRYG+ +F K+ R DG TFN+ KE+L Q++ L AV LY++RLEWL++ESRR+FGVIEEHC+ I++DIKN + + FDQ+ A ER L EQ+ IAKFNLIR E+ L+PV++++L DWLW +DR +A ++ EA+++A ++ EA+YL TE +SDGSRE+LR K+ +PL++ SYN E + +LK L +TGG+FH+Y +E+DAYE P+D +AN++LK+K +GG G G R D + VF E+EEA+ ++QI++LI +P++K I S Y +KP R +++ + AV E+YMSS+EWL GLK++KL F+D+L GV F+HCDGVVD+ + P D DF Q +A + KLINA+YCDKFAHVKWK+G +VHVQ++ +VHR Y R+ + L ++ +RI+WL+QGSRELFGT++EDQ+YILID S SM P I FVKDKL+ L+QEQLRHK K N V+FN+K PW+DR V+V E NL++AW W++ L C GSTNTL+ALQFA+ D Q +YLLTDGRPDQP +++L+Q++LQ+ +P+HTISFNC+D EAN FLC+LA++TGGR+HY++E G D N + WESEDI+LL+ E LG ++L+K+ LRDEC LAWK E VR K + R + P N + + +RPK NR + PRP A+ P+ +G + S L LSS + EW++ ET+E+ D+Q +R LE+E E + KK +++ K WL GL+ + +TILDALAPT+++ K++P++D Y +SKVF++ +P +HV S +R + LVNP +VDLKAY+ K+ + KY+K+L ++ + + F P+ +D K +++A WP+ E ++ EI G+KY +Q+ L + K G KG + ++P ++E +Q+ T KVL ++G +++A DG YY +I + V+ + A +P V P + G L +V N + +R Y+PGI+ + + +++ R+ V LY G E+T + ++ ISK Y ++ I +
Sbjct: 2 PIIGFKHMDDYDYALKKPISSRYGEGMFSKYHRTDGTTFNLTCNKEQLKQIESRLIQAVLLYKRRLEWLTTESRRIFGVIEEHCICIVLDIKNLSPQQFDQYRSAFERVLVEQVAQIAKFNLIRSAEDMVMFKPELVPVTQESLQEAKDWLWNLDRCAAFSNTATCEAVLKAMTDRNVEAVYLFTEGSASDGSRELLRTKLHGGPLPLHVASYNATSVETVGFLKQLCEVTGGKFHAYGVIMEMDAYEGVPVDPNTNRANIVLKRKTFGGVPQGAGVREDVIKVFEELEEARNTLSQIQALIEDMPDQKMI--------------ERTKSDTALSSRGGYVPRKPLMTRQSSMTDTRGRKAVDYPPPPPKEKSEQYMSSKEWLEMNGLKAKKLGFYDILGGVAFKHCDGVVDLNQKP--DYHDF--QTDARVQPKLINARYCDKFAHVKWKNGKVVHVQVTPEVHRSYERRVNVVLDSLQQRIDWLQQGSRELFGTVIEDQIYILIDTSGSMAPSIQFVKDKLFVLMQEQLRHKQKFNLVSFNSKISPWKDRCVEVNEKNLQAAWTWIKNLECVGSTNTLAALQFALADHATQAVYLLTDGRPDQPPRSILAQVQLQHAVPLHTISFNCSDKEANQFLCQLAKDTGGRYHYYSE--HGQDPDNPS---PWESEDIRLLRKELELGKENLQKIADLRDECAALAWKKENVRSCSKNHKLSSTDRVSTVPALNPSELYRSPGSNRPKSATGYRSTSHSTPTPPPRPSSATGYRPRSAGAGGRSARNRTVSCPRPASARR------------PLVAGHTRT----------------SLLRTLSSSARFSSNEWLLPETRELFDKQAKR----LEEEV-EGKVVIEKKRKKRVSNPNNMSAKMWLKHNGLLAKKLTILDALAPTMIEQNAKHIPVLDAYALSKVFDDSMPFAHV----SNRRH----IHLVNPDSVDLKAYENKVSAAVEKYKKRLDAMVWKALPATEREQFGST---EPISFEDNKLALLQALERCGWPVKESDILAMEGEISQGRKYLLQSEGLRKASEKHGHIGCSEKSESENDDASSVASSPRSMSSKGSKSSKGSRSPKGSQTKSPRGSVASSKDYEGLGEAIQSKSVKEKDKVLSSPATQRKVRKVL-DTLRGQSVIARLETDGLYYPGMVIKCTDSRHALVELHDNGKHRIATRFIIPTGGAVSRPP----LREGDYVLARVKNSETERECYVPGIVQVTPL--RSMDQARFFTVQLYTGQEATCMRNYLIKISKTRYAFAVRYISE 1228 HSP 2 Score: 94.3597 bits (233), Expect = 3.567e-15 Identity = 90/326 (27.61%), Postives = 147/326 (45.09%), Query Frame = 3
Query: 210 VSSEQWLNKFGLKASNLDSSSLYPRLGFARLEGFNDVLKKP---------------IHSRYGDNLFPKHFR-EDGLTFNVVAKKEKLLQVQQELENAVQLYQQRLEWLSSESRRLFGVIEEHCVTXXXXXXXXXXRDFDQFICAIERFLNEQIRCIAKFNLIRVQENKCQLSNNLLPVSKDNLANGIDWLWQIDRTSATNSANLVEALIRASNNKENEALYLITEDLSSDGSREVLREKVKQLKIPLNIISYNCKDPEFISYLKCLVLMTGGRFHSYLFNLEVDAYESSPLDSENPKANLLLKKKVYGG--SIGGIGT-RNDCVAV 1130
+SS++WL GLKA L + + F +G D+ +KP I++RY D H + ++G +V E ++ + + QQR++WL SR LFG + E + I+ID + + EQ+R KFNL+ + + V++ NL W W I S N + AL A + +A+YL+T+ R +L + Q +PL+ IS+NC D E +L L TGGR+H Y + + D SP +SE+ + LL+K++ G ++ I R++C A+
Sbjct: 364 MSSKEWLEMNGLKAKKLGFYDILGGVAFKHCDGVVDLNQKPDYHDFQTDARVQPKLINARYCDKF--AHVKWKNGKVVHVQVTPEVHRSYERRVNVVLDSLQQRIDWLQQGSRELFGTVIEDQIYILIDTSGSMAPSIQFVKDKLFVLMQEQLRHKQKFNLVSFNSKISPWKDRCVEVNEKNLQAA--WTW-IKNLECVGSTNTLAALQFALADHATQAVYLLTDGRPDQPPRSILAQVQLQHAVPLHTISFNCSDKEANQFLCQLAKDTGGRYHYYSEHGQ-DPDNPSPWESEDIR---LLRKELELGKENLQKIADLRDECAAL 680
BLAST of von Willebrand factor A domain containing 3B vs. TrEMBL
Match: A0A210PHG3 (von Willebrand factor A domain-containing protein 3B OS=Mizuhopecten yessoensis OX=6573 GN=KP79_PYT12196 PE=4 SV=1) HSP 1 Score: 812.757 bits (2098), Expect = 0.000e+0 Identity = 446/1091 (40.88%), Postives = 657/1091 (60.22%), Query Frame = 3
Query: 150 PEIDMKLYPTKVWNPDAKLQVSSEQWLNKFGLKASNLDSSSLYPRLGFARLEGFNDVLKKPIHSRYGDNLFPKHFR-EDGLTFNVVAKKEKLLQVQQELENAVQLYQQRLEWLSSESRRLFGVIEEHCVTXXXXXXXXXXRDFDQFICAIERFLNEQIRCIAKFNLIRVQENKCQLSNNLLPVSKDNLANGIDWLWQIDRTSATNSANLVEALIRASNNKENEALYLITEDLSSDGSREVLREKVKQL--KIPLNIISYNCKDPEFISYLKCLVLMTGGRFHSYLFNLEVDAYESSPLDSENPKANLLLKKKVYGGSIGGIGTRNDCVAVFSEIEEAKALINQIKSLINQIPEKKGIYDNHYHHKHPLRVWNHAYGQKEWESCCSYKKPHPCRYCVDDNSQSKLAVHIPREEYMSSQEWLAKYGLKSRKLDFFDVLSGVCFRHCDGVVDVLEPPPVDKLDFMEQQNATLHQKLINAKYCDKFAHVKWKDGSLVHVQMSSDVHRLYSERMKLCLLAITRRIEWLRQGSRELFGTIMEDQVYILIDISASMEPHISFVKDKLYTLIQEQLRHKSKINFVAFNTKALPWRDRLVDVTEANLKSAWQWLEGLTCQGSTNTLSALQFAIKDRNCQGIYLLTDGRPDQPTKTVLSQIRLQYRLPIHTISFNCADLEANTFLCELARETGGRFHYFNEISGGADCTNENELEAWESEDIKLLKSEYRLGFDSLEKVTKLRDECHKLAWKSEV--VRKKEQK-----STRKTMAPGCNQNPYFSQISPSRPKCENREIKYPRPIKAKNTFRKQQKEQENDPIWSGTIKLLNLDSTTVASQSDAYQSFLEALSSRDE-----------NEQEWVIDETQEIIDRQTERYKK-------------ILEDEYNEAMSXXXXXXXXXXXXXXXXXXXQWLHIYGLVPQHMTILDALAPTIVKVRPKYVPIIDKYVMSKVFEEILPISHVVTEGSPKRGYKPVVRLVNPLAVDLKAYQEKLENLMNKYRKKLRKLIQIHIGDSTLNAF--DEMLVKYPLGNDDVKRWVMKAFRDANWPMGEEELEMFMNEIYIGQKYFIQAGDL 3314
P I K P+K W D + +S+++WL +GLK + + + P +GF + F+ LK+PI SRY LF K F DG TFNV ++ L Q++ L A+ LY++RLEWL+SESRRLFGVIEE VTI++DI+N + + FDQ+ A+ER + EQ+ +AKFNLIR ++ +PV+ D + +DW+W +DR + + + EA+++A +K NEA+YL TE S D +E+++EKV L KIP++ +SYNC + + +L+ TGG+FH+Y +E+D+YE PL+ KAN+LLKKK YGG G G R D + +F E+EEAK ++QI+SL+ ++PE K D+ V + +Q + P E+YMSS++WL K+GL +R+L+ +DVL+GV F+H DGVVD+ + P D +A KL+NAKYCD+F V+WKDG +VHVQ++ ++HR Y +RM + + A +R++WL QGSR LFGT++EDQ+YILID S+SM P I FVKDKL+ L+QEQLRHK K N VAFN+KA+ W++RLV+V E +LK AW+W++GL+C GSTNT +ALQFAI D Q IYLLTDGRPDQP +++++Q+++Q+ +P+HTISFNC D EAN FLC+LAR TGGR+HYF+E G D +++ +WESEDI+LLK E G +SL+KV +LRDEC L+WK EV +R+ + + R + P N + + +P PK + + P A KQ + S ++ S S S +S L A +R + +EW++ ET+++ ++Q R K+ ILE+ + + + K K ++ K WL +GLV + +TILDALAPT V KYVPI+DK+V++KVF+ +LP++HV + K + LVNPLAVDLK Y+ K+ + +N Y+++L K++ + T + F DE PL D+ + ++KA A WP+ E ++ + EI G K+ QA +L
Sbjct: 39 PAISEKKTPSKEWELDVRSLISTKKWLQNYGLKKNKISLKQILPTIGFKHSDDFDSSLKRPISSRYSSGLFSKIFSPSDGKTFNVTCSRQMLKQLEGRLLQAIALYKRRLEWLTSESRRLFGVIEEKGVTIVLDIRNMSPQQFDQYKIALERVIFEQLTQVAKFNLIRAVDDLVSYQEECVPVTFDTIQGAVDWVWSLDRLQSVSRSAACEAVLKAMADKNNEAVYLFTEGTSIDTCKEIMKEKVAALRRKIPVHCVSYNCGSSDTVRFLRDFAPCTGGKFHAYAVIMEMDSYEGEPLNPRTNKANILLKKKTYGGVPPGSGMREDVILLFEELEEAKNNLSQIQSLMEEVPEPKIQIDS-----------------------------------VIERTQ----LTDPEEQYMSSKDWLKKFGLAARRLELYDVLAGVAFKHMDGVVDIKQKP-----DHNTHTDAVRKPKLMNAKYCDRFPVVRWKDGGVVHVQVTPEIHRSYEQRMNVAVQAFHQRVDWLNQGSRALFGTVIEDQIYILIDTSSSMTPSIQFVKDKLFILMQEQLRHKMKFNLVAFNSKAISWQNRLVEVNEQSLKGAWKWIQGLSCWGSTNTYAALQFAISDPGTQAIYLLTDGRPDQPPRSIIAQVQMQHCVPVHTISFNCNDTEANQFLCDLARNTGGRYHYFSE-KGKLD---QDQPASWESEDIRLLKEEASRGRESLDKVEELRDECSNLSWKKEVESLRRCSRSHPKSLTDRVSAVPPLNTSDLYRSSTPPPPKTLSASMDSPLMSPAPP---KQSRAYSAHRSLSSSLDFQRPKSAVPTSGSKTERSPLSASHTRTSLLRTLNSTGNFSPEEWLLPETRQLFEKQAVRQKQLAIVLQRYDMSPYILEENDETRKTSSRRSKIKKNIKPHSMSSKMWLSKHGLVAKKLTILDALAPTFVSHSAKYVPILDKHVVAKVFDGVLPLAHVSSRSRQK------ITLVNPLAVDLKGYEAKVRSAINLYKRRLDKIVWEALSQDTKDGFGSDE-----PLSFDNNRLVLIKALDTAGWPIEESDILLLEEEIARGNKFLSQAEEL 1067
BLAST of von Willebrand factor A domain containing 3B vs. Ensembl Cavefish
Match: ENSAMXT00000042735.1 (von Willebrand factor A domain containing 3A [Source:NCBI gene;Acc:103035332]) HSP 1 Score: 164.081 bits (414), Expect = 4.215e-40 Identity = 109/328 (33.23%), Postives = 176/328 (53.66%), Query Frame = 3
Query: 1356 VHIPREEYM-SSQEWLAKYGLKSRKLDFFDVLSGVCFRHCDGVVDVLEPPPVDKLDFMEQQNATLHQKLINAKYCDKFAHVKWKDGSLVHVQMSSDVHRLYSERMKLCLLAITRRIEWLRQGSRELFGTIMEDQVYILIDISASMEPHISFVKDKLYTLIQEQLRHKS-KINFVAFNTKALPWRDRLVDVTEANLKSAWQWLEGLTCQGSTNTLSALQFAIKDRNCQGIYLLTDGRPDQPTKTVLSQ---IRLQYRLPIHTISFNCADLEANTFLCELARETGGRFHYFNEISGGADCT----------NENELEAWESEDIKLLKSE 2294
V IP++E + S+++WL +G++S+KLD ++SG H +V T+H K ++AKYC F V+ +GS+ H+ +S + Y +++ L +R++WL GSR +FG ++E V +++D+S SM P + ++ +L +LI EQL S + + VAF+ + W+ LV+ +E K A QWL L+ G T++L ALQ + G+YL+TDGR D VL + + + IHTI+FNC D A FL +LA +TGGRFH S A + ++EL ++E +D++ L E
Sbjct: 762 VTIPKQEDICSTKQWLKSFGIRSQKLDLHKLVSGPECTHRKKLVR------------------TVH-KSVSAKYCAIFPSVQ-VNGSVRHLLLSPAELKQYLIQVEKVLQRYAQRMQWLLSGSRRVFGCVVERAVCVVLDVSGSMAPCVPELQKELASLIWEQLHANSVRFSMVAFSGEVRVWQVELVEASEERCKEAVQWLGQLSTHGGTSSLQALQAGCAFGDSLGVYLITDGRNDCSCSLVLKEAERLTAGKHITIHTIAFNCQDRTAKEFLRKLAHKTGGRFHEAPSESHTAAASELLTSSFSVGEDSELPSFEGDDLRRLSEE 1069 HSP 2 Score: 159.458 bits (402), Expect = 1.182e-38 Identity = 145/659 (22.00%), Postives = 277/659 (42.03%), Query Frame = 3
Query: 375 REDGLTFNVVAKKEKLLQVQQELENAVQLYQQRLEWLSSESRRLFGVIEEHCVTXXXXXXXXXXRDFDQFICAIERF----------LNEQIRCIAKFNLIRVQENKCQLSNNLLPVSKDNLANGIDWLWQIDRTSATNSANLVEALIRASNNKENEALYLI---TEDLSSDGSREVLREKVKQLKIPLNIISYNCKDPEFISYLKCLVLMTGGRFHSYLFNLEVDAYESSPLDSENPKANLLLKKKVYGGSIGGIGTRNDCVAVFSEIEEAKALINQIKSLIN------QIPEKKGIYDNHYHHKHPLRVWNHAYGQKEWESCCSYKK----PHPCRYCVDDNSQSKLAVHIPREEYMSSQEWLAKYGLKSRKLDFFDVLSGVCFRHCDGVVDVLEPPPVDKLDFMEQQNATLHQKLINAKYCDKFAHVKWKDGSLVHVQMSSDVHRLYSERMKLCLLAITRRIEWLRQ-GSRELFGTIMEDQVYILIDISASMEPHISFVKDKLYTLIQEQLRHKSKINFVAFNTKALPWRDRLVDVTEANLKSAWQWLEGLTCQGSTNTLSALQFAIK------DRNCQGIYLLTDGRPDQPTKTV---LSQIRLQYRLPIHTISFNCADLEANTF-------------LCELARETGGRFHYFNE 2213
R+DG++ + +KL + Q L LY R++WL+ SR++FG+++ + D C+ ER + EQ R + + L V+ L W+ Q++ + S NL++AL A ++ + ++L +I D +D + ++V++ +++++YN + I +K + +T GR+H ++ ++G + + +D +++EI+ A+ +++ I + + +P I ++ C S PH + + L + P +S EWL G+K++KL + VL+ + + V +L + ++T+H+K + +W DG++ +V + + + Y +R+ + R WL GSR+++G + E +V++L+D+SA + ++ ++ L+QEQL N AF + W++++V T NL+ WQW++GL C G TL+A+Q A + G+YL T G PDQ TV +S++ RL IH I F ++ A + L LA + GRFH+ +
Sbjct: 91 RDDGVSTQLEIDSKKLFETQ--LYQVTDLYHSRIQWLNQGSRKMFGIVK--------GSRLGVLIDVSDVNCSEERLEDLQHHLLLLIEEQFRMKKVLHFMSFGTELSSLWTGPKEVTPLRLKESQQWVLQLE---PSGSCNLLQALKTACSHTQLDSLLIILGSCPDQDTDSIFNYMTQEVQEKVTSIHVVAYNTCNQVAIENVKNIAKVTEGRYH------------------------------IFSAALGVVDSSSDLEPLWAEIKSARDVLDHIHCMSHGQLEDLTVPVMSEISED--------------------LDCLSLSDLKSDPH--------DGSAALCIQPPTLLPTTSAEWLKTNGMKAKKLSLYQVLAPNVYSPKESFVPILR----------KTVHSTVHEKAM--------VQFEWHDGTVKNVHVDLPLLQNYQKRLLEAEQVLEDRAAWLSSTGSRQIWGAVCEQRVHVLLDMSAMNNHYQLHIQHAVHLLLQEQLPSTHSFNITAFGSDIKQWKEQMVPPTSENLQDVWQWIQGLECGGDRYTLAAIQHAAEAELSTDSSLTSGVYLFTTGMPDQDPVTVSTYMSEVCNNPRLKIHVILFAGENMLARSLTPRYVTWAETAQVLRGLAHASKGRFHWITD 660 HSP 3 Score: 93.2041 bits (230), Expect = 2.140e-18 Identity = 64/231 (27.71%), Postives = 112/231 (48.48%), Query Frame = 3
Query: 1572 YCDKFAHVKWKDGSLVHVQMSSDVHRLYSERMKLCLLAITRRIEWLRQGSRELFGTIMEDQVYILIDIS--ASMEPHISFVKDKLYTLIQEQLRHKSKINFVAFNTKALPWRDRLVDVTEANLKSAWQWLEGLTCQGSTNTLSALQFAIKDRNCQGIYLLTDGRPDQPTKTVLSQIRLQYR---LPIHTISFNCADLEANTFLCELARETGGRFHYFNEISGGADCTNENE 2249
+C A DG V Q+ D +L+ ++ RI+WL QGSR++FG + ++ +LID+S E + ++ L LI+EQ R K ++F++F T+ +VT LK + QW+ L GS N L AL+ A + ++ PDQ T ++ + + + + IH +++N + A + +A+ T GR+H F+ G D +++ E
Sbjct: 82 HCSTAATSSRDDG--VSTQLEIDSKKLFETQLYQVTDLYHSRIQWLNQGSRKMFGIVKGSRLGVLIDVSDVNCSEERLEDLQHHLLLLIEEQFRMKKVLHFMSFGTELSSLWTGPKEVTPLRLKESQQWVLQLEPSGSCNLLQALKTACSHTQLDSLLIILGSCPDQDTDSIFNYMTQEVQEKVTSIHVVAYNTCNQVAIENVKNIAKVTEGRYHIFSAALGVVDSSSDLE 310 HSP 4 Score: 80.8777 bits (198), Expect = 1.301e-14 Identity = 67/276 (24.28%), Postives = 127/276 (46.01%), Query Frame = 3
Query: 171 YPTKVWNPDAKLQVSSEQWLNKFGLKASNLDSSSLYPRLGFARLEGFNDVLKKPIHSRYGDNLFPKHFREDGLTFNVVAKKEKLLQVQQELENAVQLYQQRLEWLSSESRRLFGVIEEHCVTXXXXXXXXXXRDFDQFICAIERFLNEQIRC-IAKFNLIRVQENKCQLSNNLLPVSKDNLANGIDWLWQIDRTSATNSANLVEALIRASNNKENEALYLITEDLSSDGSREVLREKVKQLK---IPLNIISYNCKDPEFISYLKCLVLMTGGRFH 986
Y + V P + S++QWL FG+++ LD L + + K + ++Y +FP + +G +++ +L Q ++E +Q Y QR++WL S SRR+FG + E V +++D+ + + + EQ+ +F+++ L+ S++ + WL Q+ T+S ++AL ++ +YLIT+ + VL+E + I ++ I++NC+D +L+ L TGGRFH
Sbjct: 758 YISTVTIPKQEDICSTKQWLKSFGIRSQKLDLHKLVSGPECTHRKKLVRTVHKSVSAKYC-AIFPS-VQVNGSVRHLLLSPAELKQYLIQVEKVLQRYAQRMQWLLSGSRRVFGCVVERAVCVVLDVSGSMAPCVPELQKELASLIWEQLHANSVRFSMVAFSGEVRVWQVELVEASEERCKEAVQWLGQLSTHGGTSS---LQALQAGCAFGDSLGVYLITDGRNDCSCSLVLKEAERLTAGKHITIHTIAFNCQDRTAKEFLRKLAHKTGGRFH 1028 HSP 5 Score: 61.6178 bits (148), Expect = 1.145e-8 Identity = 68/289 (23.53%), Postives = 124/289 (42.91%), Query Frame = 3
Query: 192 PDAKLQVSSEQWLNKFGLKASNLDSSSLYPRLG---FARLEGFNDVLKKPIHSRYGDNLFPKHFREDGLTFNVVAKKEKLLQVQQELENAVQLYQQRLEWLSSE-SRRLFGVIEEHCVTXXXXXXXXXXRDFDQFICAIERFLNEQIRCIAKFNLIRVQENKCQLSNNLLPVSKDNLANGIDWLWQI----DRTSATNSANLVEALIRASNNKENEALYLITEDLSSDGSREV---LREKVKQLKIPLNIISYNCKD-------PEFISY------LKCLVLMTGGRFH 986
P L +S +WL G+KA L SLY L ++ E F +L+K +HS + + DG NV L Q+ L A Q+ + R WLSS SR+++G + E V +++D+ N A+ L EQ+ FN+ + Q ++P + +NL + W+ + DR + + EA + ++++ +YL T + V + E ++ +++I + ++ P ++++ L+ L + GRFH
Sbjct: 372 PPTLLPTTSAEWLKTNGMKAKKL---SLYQVLAPNVYSPKESFVPILRKTVHSTVHEKAMVQFEWHDGTVKNVHVDLPLLQNYQKRLLEAEQVLEDRAAWLSSTGSRQIWGAVCEQRVHVLLDMSAMNNHYQLHIQHAVHLLLQEQLPSTHSFNITAFGSDIKQWKEQMVPPTSENLQDVWQWIQGLECGGDRYTLAAIQHAAEAEL-STDSSLTSGVYLFTTGMPDQDPVTVSTYMSEVCNNPRLKIHVILFAGENMLARSLTPRYVTWAETAQVLRGLAHASKGRFH 656
BLAST of von Willebrand factor A domain containing 3B vs. Ensembl Cavefish
Match: ENSAMXT00000000373.2 (von Willebrand factor A domain containing 3A [Source:NCBI gene;Acc:103035332]) HSP 1 Score: 164.081 bits (414), Expect = 4.379e-40 Identity = 109/329 (33.13%), Postives = 176/329 (53.50%), Query Frame = 3
Query: 1353 AVHIPREEYM-SSQEWLAKYGLKSRKLDFFDVLSGVCFRHCDGVVDVLEPPPVDKLDFMEQQNATLHQKLINAKYCDKFAHVKWKDGSLVHVQMSSDVHRLYSERMKLCLLAITRRIEWLRQGSRELFGTIMEDQVYILIDISASMEPHISFVKDKLYTLIQEQLRHKS-KINFVAFNTKALPWRDRLVDVTEANLKSAWQWLEGLTCQGSTNTLSALQFAIKDRNCQGIYLLTDGRPDQPTKTVLSQ---IRLQYRLPIHTISFNCADLEANTFLCELARETGGRFHYFNEISGGADCT----------NENELEAWESEDIKLLKSE 2294
V IP++E + S+++WL +G++S+KLD ++SG H +V T+H K ++AKYC F V+ +GS+ H+ +S + Y +++ L +R++WL GSR +FG ++E V +++D+S SM P + ++ +L +LI EQL S + + VAF+ + W+ LV+ +E K A QWL L+ G T++L ALQ + G+YL+TDGR D VL + + + IHTI+FNC D A FL +LA +TGGRFH S A + ++EL ++E +D++ L E
Sbjct: 816 TVTIPKQEDICSTKQWLKSFGIRSQKLDLHKLVSGPECTHRKKLVR------------------TVH-KSVSAKYCAIFPSVQ-VNGSVRHLLLSPAELKQYLIQVEKVLQRYAQRMQWLLSGSRRVFGCVVERAVCVVLDVSGSMAPCVPELQKELASLIWEQLHANSVRFSMVAFSGEVRVWQVELVEASEERCKEAVQWLGQLSTHGGTSSLQALQAGCAFGDSLGVYLITDGRNDCSCSLVLKEAERLTAGKHITIHTIAFNCQDRTAKEFLRKLAHKTGGRFHEAPSESHTAAASELLTSSFSVGEDSELPSFEGDDLRRLSEE 1124 HSP 2 Score: 159.844 bits (403), Expect = 9.674e-39 Identity = 169/771 (21.92%), Postives = 317/771 (41.12%), Query Frame = 3
Query: 375 REDGLTFNVVAKKEKLLQVQQELENAVQLYQQRLEWLSSESRRLFGVIEEHCVTXXXXXXXXXXRDFDQFICAIERF----------LNEQIRCIAKFNLIRVQENKCQLSNNLLPVSKDNLANGIDWLWQIDRTSATNSANLVEALIRASNNKENEALYLI---TEDLSSDGSREVLREKVKQLKIPLNIISYNCKDPEFISYLKCLVLMTGGRFHSYLFNLEVDAYESSPLDSENPKANLLLKKKVYGGSIGGIGTRNDCVAVFSEIEEAKALINQIKSLIN------QIPEKKGIYDNHYHHKHPLRVWNHAYGQKEWESCCSYKK----PHPCRYCVDDNSQSKLAVHIPREEYMSSQEWLAKYGLKSRKLDFFDVLSGVCFRHCDGVVDVLEPPPVDKLDFMEQQNATLHQKLINAKYCDKFAHVKWKDGSLVHVQMSSDVHRLYSERMKLCLLAITRRIEWLRQ-GSRELFGTIMEDQVYILIDISASMEPHISFVKDKLYTLIQEQLRHKSKINFVAFNTKALPWRDRLVDVTEANLKSAWQWLEGLTCQGSTNTLSALQFAIK------DRNCQGIYLLTDGRPDQPTKTV---LSQIRLQYRLPIHTISFNCADLEANTF-------------LCELARETGGRFHYFNEISGGADCTNENELEAWESEDIKLLKSEYRLGFDSLEKVTKLRDECHKLAWKSEVVRKKEQKSTRKTMAP-GCNQN-PYFSQISPSRP------KCENREIKYP---RPIKAK 2516
R+DG++ + +KL + Q L LY R++WL+ SR++FG+++ + D C+ ER + EQ R + + L V+ L W+ Q++ + S NL++AL A ++ + ++L +I D +D + ++V++ +++++YN + I +K + +T GR+H ++ ++G + + +D +++EI+ A+ +++ I + + +P I ++ C S PH + + L + P +S EWL G+K++KL + VL+ + + V +L + ++T+H+K + +W DG++ +V + + + Y +R+ + R WL GSR+++G + E +V++L+D+SA + ++ ++ L+QEQL N AF + W++++V T NL+ WQW++GL C G TL+A+Q A + G+YL T G PDQ TV +S++ RL IH I F ++ A + L LA + GRFH+ + ES+D+ L E + +K +L D L +S E+ +++ P C+Q ++ P RP + E++E K RP AK
Sbjct: 91 RDDGVSTQLEIDSKKLFETQ--LYQVTDLYHSRIQWLNQGSRKMFGIVK--------GSRLGVLIDVSDVNCSEERLEDLQHHLLLLIEEQFRMKKVLHFMSFGTELSSLWTGPKEVTPLRLKESQQWVLQLE---PSGSCNLLQALKTACSHTQLDSLLIILGSCPDQDTDSIFNYMTQEVQEKVTSIHVVAYNTCNQVAIENVKNIAKVTEGRYH------------------------------IFSAALGVVDSSSDLEPLWAEIKSARDVLDHIHCMSHGQLEDLTVPVMSEISED--------------------LDCLSLSDLKSDPH--------DGSAALCIQPPTLLPTTSAEWLKTNGMKAKKLSLYQVLAPNVYSPKESFVPILR----------KTVHSTVHEKAM--------VQFEWHDGTVKNVHVDLPLLQNYQKRLLEAEQVLEDRAAWLSSTGSRQIWGAVCEQRVHVLLDMSAMNNHYQLHIQHAVHLLLQEQLPSTHSFNITAFGSDIKQWKEQMVPPTSENLQDVWQWIQGLECGGDRYTLAAIQHAAEAELSTDSSLTSGVYLFTTGMPDQDPVTVSTYMSEVCNNPRLKIHVILFAGENMLARSLTPRYVTWAETAQVLRGLAHASKGRFHWITDTG------------IVESDDVIALIGEMETAANYWQKCCELLD---SLVQRSSSRMDAEEAQSQECCNPVQCSQTWTRGHKLPPPRPTQLSLARLESKEGKRSQTWRPSSAK 757 HSP 3 Score: 93.2041 bits (230), Expect = 2.415e-18 Identity = 64/231 (27.71%), Postives = 112/231 (48.48%), Query Frame = 3
Query: 1572 YCDKFAHVKWKDGSLVHVQMSSDVHRLYSERMKLCLLAITRRIEWLRQGSRELFGTIMEDQVYILIDIS--ASMEPHISFVKDKLYTLIQEQLRHKSKINFVAFNTKALPWRDRLVDVTEANLKSAWQWLEGLTCQGSTNTLSALQFAIKDRNCQGIYLLTDGRPDQPTKTVLSQIRLQYR---LPIHTISFNCADLEANTFLCELARETGGRFHYFNEISGGADCTNENE 2249
+C A DG V Q+ D +L+ ++ RI+WL QGSR++FG + ++ +LID+S E + ++ L LI+EQ R K ++F++F T+ +VT LK + QW+ L GS N L AL+ A + ++ PDQ T ++ + + + + IH +++N + A + +A+ T GR+H F+ G D +++ E
Sbjct: 82 HCSTAATSSRDDG--VSTQLEIDSKKLFETQLYQVTDLYHSRIQWLNQGSRKMFGIVKGSRLGVLIDVSDVNCSEERLEDLQHHLLLLIEEQFRMKKVLHFMSFGTELSSLWTGPKEVTPLRLKESQQWVLQLEPSGSCNLLQALKTACSHTQLDSLLIILGSCPDQDTDSIFNYMTQEVQEKVTSIHVVAYNTCNQVAIENVKNIAKVTEGRYHIFSAALGVVDSSSDLE 310 HSP 4 Score: 80.8777 bits (198), Expect = 1.275e-14 Identity = 67/276 (24.28%), Postives = 127/276 (46.01%), Query Frame = 3
Query: 171 YPTKVWNPDAKLQVSSEQWLNKFGLKASNLDSSSLYPRLGFARLEGFNDVLKKPIHSRYGDNLFPKHFREDGLTFNVVAKKEKLLQVQQELENAVQLYQQRLEWLSSESRRLFGVIEEHCVTXXXXXXXXXXRDFDQFICAIERFLNEQIRC-IAKFNLIRVQENKCQLSNNLLPVSKDNLANGIDWLWQIDRTSATNSANLVEALIRASNNKENEALYLITEDLSSDGSREVLREKVKQLK---IPLNIISYNCKDPEFISYLKCLVLMTGGRFH 986
Y + V P + S++QWL FG+++ LD L + + K + ++Y +FP + +G +++ +L Q ++E +Q Y QR++WL S SRR+FG + E V +++D+ + + + EQ+ +F+++ L+ S++ + WL Q+ T+S ++AL ++ +YLIT+ + VL+E + I ++ I++NC+D +L+ L TGGRFH
Sbjct: 813 YISTVTIPKQEDICSTKQWLKSFGIRSQKLDLHKLVSGPECTHRKKLVRTVHKSVSAKYC-AIFPS-VQVNGSVRHLLLSPAELKQYLIQVEKVLQRYAQRMQWLLSGSRRVFGCVVERAVCVVLDVSGSMAPCVPELQKELASLIWEQLHANSVRFSMVAFSGEVRVWQVELVEASEERCKEAVQWLGQLSTHGGTSS---LQALQAGCAFGDSLGVYLITDGRNDCSCSLVLKEAERLTAGKHITIHTIAFNCQDRTAKEFLRKLAHKTGGRFH 1083 HSP 5 Score: 60.8474 bits (146), Expect = 1.684e-8 Identity = 68/289 (23.53%), Postives = 124/289 (42.91%), Query Frame = 3
Query: 192 PDAKLQVSSEQWLNKFGLKASNLDSSSLYPRLG---FARLEGFNDVLKKPIHSRYGDNLFPKHFREDGLTFNVVAKKEKLLQVQQELENAVQLYQQRLEWLSSE-SRRLFGVIEEHCVTXXXXXXXXXXRDFDQFICAIERFLNEQIRCIAKFNLIRVQENKCQLSNNLLPVSKDNLANGIDWLWQI----DRTSATNSANLVEALIRASNNKENEALYLITEDLSSDGSREV---LREKVKQLKIPLNIISYNCKD-------PEFISY------LKCLVLMTGGRFH 986
P L +S +WL G+KA L SLY L ++ E F +L+K +HS + + DG NV L Q+ L A Q+ + R WLSS SR+++G + E V +++D+ N A+ L EQ+ FN+ + Q ++P + +NL + W+ + DR + + EA + ++++ +YL T + V + E ++ +++I + ++ P ++++ L+ L + GRFH
Sbjct: 372 PPTLLPTTSAEWLKTNGMKAKKL---SLYQVLAPNVYSPKESFVPILRKTVHSTVHEKAMVQFEWHDGTVKNVHVDLPLLQNYQKRLLEAEQVLEDRAAWLSSTGSRQIWGAVCEQRVHVLLDMSAMNNHYQLHIQHAVHLLLQEQLPSTHSFNITAFGSDIKQWKEQMVPPTSENLQDVWQWIQGLECGGDRYTLAAIQHAAEAEL-STDSSLTSGVYLFTTGMPDQDPVTVSTYMSEVCNNPRLKIHVILFAGENMLARSLTPRYVTWAETAQVLRGLAHASKGRFH 656
BLAST of von Willebrand factor A domain containing 3B vs. Ensembl Cavefish
Match: si:dkey-8l13.5 (chromosome 18 C11orf16 homolog [Source:NCBI gene;Acc:103047275]) HSP 1 Score: 69.707 bits (169), Expect = 2.430e-11 Identity = 52/176 (29.55%), Postives = 84/176 (47.73%), Query Frame = 3
Query: 1719 SRELFGTIM--EDQVYILIDISASMEPHISFVKDKLY-TLIQEQLRHKSKINFVAFNTKALPWRDRLVDVTEANLKSAWQWLEGLTCQGSTNTLSALQFAIKDRNCQGIYLLTDGRPDQPTKTVLSQIRLQYRLPIHTISFNCAD---LEANT--FLCELARETGGRFHYFNEISG 2222
SR + +M + V +++D S +M + VK+ + TL+ + S N + F+ K PW D +V + A W+ LT + L+AL A D CQ ++L+T+ PD P + LS + P+HT F+ A+ L+++T FL L T G + N SG
Sbjct: 4 SRGVIPVLMGKDRNVTLILDTSEAMTAVLGTVKNLIVQTLLAKASLRNSLFNIITFSYKVTPWSDHMVPCAPDTVYEALGWIHTLTTSPGKDLLTALTTAFSDPACQSVHLVTNSLPDNP-ENCLSALSTCGTRPVHT--FHIAEKQALDSDTLDFLKCLTSATRGSCYRLNLNSG 176
BLAST of von Willebrand factor A domain containing 3B vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001432.1 (pep scaffold:Pmarinus_7.0:GL485617:3236:10216:1 gene:ENSPMAG00000001295.1 transcript:ENSPMAT00000001432.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 244.202 bits (622), Expect = 6.481e-71 Identity = 157/473 (33.19%), Postives = 234/473 (49.47%), Query Frame = 3
Query: 687 LPVSKDNLANGIDWLWQIDRTSA-TNSANLVEALIRASNNKENEALYLITEDLSSDGSREVLREKVKQLKIPLNIISYNCKDPE-FISYLKCLVLMTGGRFHSYLF-------NLEVD-AYESSPLD--SENPKANLLLKKKVYGGSIGGIGTRNDCVAVFSEIEEAKALINQIKSLINQIPEKKGIYDNHYHHKHPLRVWNHAYGQKEW-ESCCSYKKPHPCRYCVDDNSQSKLAVHIPREEYMSSQEWLAKYGLKSRKLDFFDVLSGVCFRHCDGVVDVLEPPPVDKLDFMEQQNATLHQKLINAKYCDKFAHVKWKDGSLVHVQMSSDVHRLYSERMKLCLLAITRRIEWLRQGSRELFGTIMEDQVYILIDISASMEPHISFVKDKLYTLIQEQLRHKSKINFVAFNTKALPWRDRLVDVTEANLKSAWQWLEGLTCQGSTNTLSALQFAIKDRNCQGIYLLTDGRPDQ 2066
+PV+ +L + WL ++ +A EAL A + EA+ L+ RE++R+ V+ P+++ + P S+L+ + +TGGRFH+ + +L D A +S D S +P + +V +G + D V+ E EEA ++ +I+ ++ +I ++ W E C S + E SS+ WLA+YGL++R L L FRH DGVVD + L+NA+YC F H W DG+LVHV + V+R Y+ R+ L I R+EWL++GSR LFG+I+ED+VYILID S SME + +K+KLY LI EQLR+KS N V F ++A WR ++VD TE++L A W+E L GST+TL AL+ A+ D +G+YLL+DGRPDQ
Sbjct: 6 VPVTPQSLLSASSWLRSLEAQAAPCGGTACAEALTHALGDPTVEAVCLVVAGPVEGVFRELMRKAVRTAGRPVHVACVDAAAPSPSRSFLREIADLTGGRFHTCVLTSFAESVSLARDTAVSASQGDHVSCDPPPTTSPRWRV------AVGVQQDVWEVWKEREEASQILGEIRLILREISAPSATSED----------------ADSWSEDCASVRSA---------------------EAEQSSRAWLARYGLEARGLALHTALGRCAFRHADGVVDSAHGDCA-----CACAQGRRRRVLVNARYCSCFVHTLWADGALVHVYVPERVYRDYAVRLTAALRLIQSRLEWLQRGSRALFGSIVEDRVYILIDTSLSMEDKLDLLKEKLYLLIDEQLRYKSGFNLVRFGSRAGAWRRQIVDTTESHLDDARAWVESLEAGGSTDTLGALRLALGDPATEGVYLLSDGRPDQ 430 HSP 2 Score: 63.1586 bits (152), Expect = 3.395e-10 Identity = 57/227 (25.11%), Postives = 96/227 (42.29%), Query Frame = 3
Query: 198 AKLQVSSEQWLNKFGLKASNLDSSSLYPRLGFARLEGFNDVL--------------KKPIHSRYGDNLFPKHFREDGLTFNVVAKKEKLLQVQQELENAVQLYQQRLEWLSSESRRLFGVIEEHCVTXXXXXXXXXXRDFDQFICAIERFLNEQIRCIAKFNLIRVQENKCQLSNNLLPVSKDNLANGIDWLWQIDRTSATNSANLVEALIRASNNKENEALYLITE 836
A+ + SS WL ++GL+A L + R F +G D + +++RY + F DG +V + L A++L Q RLEWL SR LFG I E V I+ID + D + ++EQ+R + FNL+R ++ ++ +L + W ++ A S + + AL A + E +YL+++
Sbjct: 203 AEAEQSSRAWLARYGLEARGLALHTALGRCAFRHADGVVDSAHGDCACACAQGRRRRVLVNARYC-SCFVHTLWADGALVHVYVPERVYRDYAVRLTAALRLIQSRLEWLQRGSRALFGSIVEDRVYILIDTSLSMEDKLDLLKEKLYLLIDEQLRYKSGFNLVRFGSRAGAWRRQIVDTTESHLDDARAW---VESLEAGGSTDTLGALRLALGDPATEGVYLLSD 425 HSP 3 Score: 50.0618 bits (118), Expect = 4.831e-6 Identity = 37/111 (33.33%), Postives = 50/111 (45.05%), Query Frame = 3
Query: 1896 WRDRLVDVTEANLKSAWQWLEGLTCQ----GSTNTLSALQFAIKDRNCQGIYLLTDGRPDQPTKTVLSQI-RLQYRLPIHTISFNCADLEA----NTFLCELARETGGRFH 2201
W++R V VT +L SA WL L Q G T AL A+ D + + L+ G P + V ++ R R + C D A +FL E+A TGGRFH
Sbjct: 1 WQERAVPVTPQSLLSASSWLRSLEAQAAPCGGTACAEALTHALGDPTVEAVCLVVAG----PVEGVFRELMRKAVRTAGRPVHVACVDAAAPSPSRSFLREIADLTGGRFH 107
BLAST of von Willebrand factor A domain containing 3B vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008921.1 (pep scaffold:Pmarinus_7.0:GL477596:1845:16253:1 gene:ENSPMAG00000008072.1 transcript:ENSPMAT00000008921.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 78.9518 bits (193), Expect = 3.883e-16 Identity = 45/168 (26.79%), Postives = 84/168 (50.00%), Query Frame = 3
Query: 1596 KWKDGSLVHVQMSSDVHRLYSERMKLCLLAITRRIEWLRQGSRELFGTIMEDQVYILIDISASMEPHISFVKDKLYTLIQEQLRHKSKINFVAFNTKALPWRDRLVDVTEANLKSAWQWLEGLTCQGSTNTLSALQFAIKDRNC--QGIYLLTDGRPDQPTKTVLSQI 2093
+W +G++ ++ + Y +++ + +R+ WL GSR ++GT+ E ++ +L+D+S ++ V+ + L+Q QL K N + F +R V + NL++AW W+ C G + L AL+ ++D +GIY+ T G PDQ V +
Sbjct: 8 EWHNGTVKNMHVDLPTLHNYQKQLGQAVRTYEQRVSWLSSGSRRIWGTVCEMRLAVLVDLSEMNANYLVHVQHSMRLLLQTQLTGKESFNIITFGMDIQAFRPSPVPPSPENLQAAWSWVLEWRCGGGRDLLGALRLLLEDPEGPPEGIYVFTSGVPDQDLVAVCGYV 175
BLAST of von Willebrand factor A domain containing 3B vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008919.1 (pep scaffold:Pmarinus_7.0:GL477596:1845:16253:1 gene:ENSPMAG00000008072.1 transcript:ENSPMAT00000008919.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 78.9518 bits (193), Expect = 4.077e-16 Identity = 44/159 (27.67%), Postives = 82/159 (51.57%), Query Frame = 3
Query: 1596 KWKDGSLVHVQMSSDVHRLYSERMKLCLLAITRRIEWLRQGSRELFGTIMEDQVYILIDISASMEPHISFVKDKLYTLIQEQLRHKSKINFVAFNTKALPWRDRLVDVTEANLKSAWQWLEGLTCQGSTNTLSALQFAIKDRNC--QGIYLLTDGRPDQ 2066
+W +G++ ++ + Y +++ + +R+ WL GSR ++GT+ E ++ +L+D+S ++ V+ + L+Q QL K N + F +R V + NL++AW W+ C G + L AL+ ++D +GIY+ T G PDQ
Sbjct: 8 EWHNGTVKNMHVDLPTLHNYQKQLGQAVRTYEQRVSWLSSGSRRIWGTVCEMRLAVLVDLSEMNANYLVHVQHSMRLLLQTQLTGKESFNIITFGMDIQAFRPSPVPPSPENLQAAWSWVLEWRCGGGRDLLGALRLLLEDPEGPPEGIYVFTSGVPDQ 166
BLAST of von Willebrand factor A domain containing 3B vs. Ensembl Sea Lamprey
Match: ENSPMAT00000003782.1 (pep scaffold:Pmarinus_7.0:GL476420:834400:835910:-1 gene:ENSPMAG00000003456.1 transcript:ENSPMAT00000003782.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 73.1738 bits (178), Expect = 1.227e-15 Identity = 41/97 (42.27%), Postives = 57/97 (58.76%), Query Frame = 3
Query: 2826 WLHIYGLVPQHMTILDALAPTIVKVRPKYVPIIDKYVMSKVFEEILPISHVVTEGSPKRGYKPVVRLVNPLAVDLKAYQEKLENLMNKYRKKLRKLI 3116
WL LV + +TI+DAL PT + V YVPI+ K V SKVF EI+P++ G+ V+LVNPLAV+L AY+ +L + Y K L ++
Sbjct: 5 WLARNSLVAKRLTIMDALQPTALPVSATYVPILGKNVHSKVFNEIMPLAFESHGGAR-------VQLVNPLAVNLTAYEARLTKQIEAYEKHLDSMV 94
BLAST of von Willebrand factor A domain containing 3B vs. Ensembl Nematostella
Match: EDO28327 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T6S8]) HSP 1 Score: 221.09 bits (562), Expect = 1.994e-60 Identity = 104/193 (53.89%), Postives = 135/193 (69.95%), Query Frame = 3
Query: 1785 MEPHISFVKDKLYTLIQEQLRHKSKINFVAFNTKALPWRDRLVDVTEANLKSAWQWLEGLTCQGSTNTLSALQFAIKDRNCQGIYLLTDGRPDQPTKTVLSQIRLQYRLPIHTISFNCADLEANTFLCELARETGGRFHYFNEISGGADCTNENELEAWESEDIKLLKSEYRLGFDSLEKVTKLRDECHKLAW 2363
M + VKDKLY L+QEQLRHK K N + ++T+ WRDRLVD NL +AWQW++GL+ GSTNTL+AL+ A+ D C+ IYLLTDGRPDQP ++L+Q+ L +PIHTISFNCAD EAN FLC+LA +T RFHYF+E D + N + +ESED++LL+ E G L+KV LR+EC +L W
Sbjct: 1 MSSRLFLVKDKLYRLMQEQLRHKVKFNLMKYDTRVQAWRDRLVDCNSHNLDNAWQWVKGLSTGGSTNTLAALKLALTDPQCRAIYLLTDGRPDQPPSSILAQVHLLNPVPIHTISFNCADTEANEFLCKLAADTNARFHYFSE-----DGYDVNGPKPFESEDLRLLREEIEKGLKDLKKVALLRNECSQLDW 188 HSP 2 Score: 88.5817 bits (218), Expect = 1.336e-17 Identity = 86/342 (25.15%), Postives = 151/342 (44.15%), Query Frame = 3
Query: 2673 EWVIDETQEIIDRQTERYKKILEDEYNEAMSXXXXXXXXXXXXXXXXXXXQWLHIYGLVPQHMTILDALAPTIVKVRPKYVPIIDKYVMSKVFEEI-------------------------------------LPISHVVTEGSPKRGYKPVVRLVNPLAVDLKAYQEKLENLMNKYRKKLRKLIQIHIGDSTLNAFDEMLVKYPLGNDDVKRWVMKAFRDANWPMGEEELEMFMNEIYIGQKYFIQAGDLLRIRGKTGPGKGGKDETPEFEPFDGELQNTNEPFSKVLLAA---------------MKGATILAPGPEDGYYYDAQIINWPNCDFVDVQFN 3542
+W++ ET+E + R E Y+K K+ K +D+ +K+WL YGL Q +TILDAL+PT++ KYVPI++K+++SKVF+++ LP++H T GS + V+LVNP AV+LKAY+ KL++ ++ +KL +L+ + D + E V L + + +MK + W + +E++ EI + Q+ DL +T + ++ + + E++N F ++ ++ +LA DG+YY + N +V+V FN
Sbjct: 242 DWMMRETREYLARNPEDYRKP-----RGRGRTKKRRTAKKDIDDRDMPVKKWLKKYGLAAQKLTILDALSPTLIPHTTKYVPILNKHILSKVFDQVFDQVIQGQIIPTLYPTHPNTYIPILDNHILSKVFDQVLPLAH--TSGSNRDE----VQLVNPQAVNLKAYEIKLQSAIDLLTRKLDELVYFGLSDQERVKYPEEKVPSFLQH---RESMMKDLEEQEWQVPQEDILALEREISQANTFMQQSMDL-----RTTSEQAAREIAEQQKRAREEMENKR--FKTIMEKPAAAPAQPTPQGNKFRLRHHKVLARNEVDGFYYPGLVSKCINSRYVEVDFN 562 HSP 3 Score: 59.3066 bits (142), Expect = 1.454e-8 Identity = 46/163 (28.22%), Postives = 74/163 (45.40%), Query Frame = 3
Query: 600 RFLNEQIRCIAKFNLIRVQENKCQLSNNLLPVSKDNLANGIDWLWQIDRTSATNSANLVEALIRASNNKENEALYLITEDLSSDGSREVLREKVKQLKIPLNIISYNCKDPEFISYLKCLVLMTGGRFHSYLFNLEVDAYESSPLDSENPKANLLLKKKVYGG 1088
R + EQ+R KFNL++ + L+ + NL N W W + S S N + AL A + + A+YL+T+ +L + +P++ IS+NC D E +L L T RFH Y D P +SE+ + LL++++ G
Sbjct: 14 RLMQEQLRHKVKFNLMKYDTRVQAWRDRLVDCNSHNLDNA--WQW-VKGLSTGGSTNTLAALKLALTDPQCRAIYLLTDGRPDQPPSSILAQVHLLNPVPIHTISFNCADTEANEFLCKLAADTNARFH-YFSEDGYDVNGPKPFESEDLR---LLREEIEKG 169
BLAST of von Willebrand factor A domain containing 3B vs. Ensembl Nematostella
Match: EDO41655 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S3S3]) HSP 1 Score: 100.138 bits (248), Expect = 7.892e-24 Identity = 60/164 (36.59%), Postives = 85/164 (51.83%), Query Frame = 3
Query: 1728 LFGTIMEDQVYILIDISASMEPHISFVKDKLYTLI--QEQLRHKSKINFVAFNTKALPWRDRLVDVTEANLKSAWQWLEGLTCQGSTNTLSALQFAIKDRNCQGIYLLTDGRPDQPTKTVLSQIR-LQYRLPIHTISFNC---ADLEANTFLCELARETGGRFH 2201
+FG I+E V L+D S SM + V++ L ++ + + N + FN + W DR+V T + A +W+ L C STNT+ AL A D Q IYL+TDG PDQ ++ +R L PIH I + C AD+ A FL +LA+ET G H
Sbjct: 15 IFGNILERNVVFLLDTSGSMYHCLDVVREHLIEILFFRATSGRDTMFNVIEFNEEVTKWADRMVQCTPRTVSVASEWINKLQCGTSTNTMGALLEAYDDDGMQAIYLVTDGMPDQRPGIIMENVRKLHKGRPIHAI-YLCGAKADVAAVEFLEDLAKETNGSLH 177
BLAST of von Willebrand factor A domain containing 3B vs. Planmine SMEST
Match: SMESG000047774.1 (SMESG000047774.1) HSP 1 Score: 3839.27 bits (9955), Expect = 0.000e+0 Identity = 2039/2157 (94.53%), Postives = 2042/2157 (94.67%), Query Frame = 3
Query: 45 MYEMKNTPNVQISPTFDLPKKNIVSTIKRTDAVIVPEIDMKLYPTKVWNPDAKLQVSSEQWLNKFGLKASNLDSSSLYPRLGFARLEGFNDVLKKPIHSRYGDNLFPKHFREDGLTFNVVAKKEKLLQVQQELENAVQLYQQRLEWLSSESRRLFGVIEEHCVTXXXXXXXXXXRDFDQFICAIERFLNEQIRCIAKFNLIRVQENKCQLSNNLLPVSKDNLANGIDWLWQIDRTSATNSANLVEALIRASNNKENEALYLITEDLSSDGSREVLREKVKQLKIPLNIISYNCKDPEFISYLKCLVLMTGGRFHSYLFNLEVDAYESSPLDSENPKANLLLKKKVYGGSIGGIGTRNDCVAVFSEIEEAKALINQIKSLINQIPEKKGIYDNHYHHKHPLRVWNHAYGQKEWESCCSYKKPHPCRYCVDDNSQSKLAVHIPREEYMSSQEWLAKYGLKSRKLDFFDVLSGVCFRHCDGVVDVLEPPPVDKLDFMEQQNATLHQKLINAKYCDKFAHVKWKDGSLVHVQMSSDVHRLYSERMKLCLLAITRRIEWLRQGSRELFGTIMEDQVYILIDISASMEPHISFVKDKLYTLIQEQLRHKSKINFVAFNTKALPWRDRLVDVTEANLKSAWQWLEGLTCQGSTNTLSALQFAIKDRNCQGIYLLTDGRPDQPTKTVLSQIRLQYRLPIHTISFNCADLEANTFLCELARETGGRFHYFNEISGGADCTNENELEAWESEDIKLLKSEYRLGFDSLEKVTKLRDECHKLAWKSEVVRKKEQKSTRKTMAPGCNQNPYFSQISPSRPKCENREIKYPRPIKAKNTFRKQQKEQENDPIWSGTIKLLNLDSTTVASQSDAYQSFLEALSSRDENEQEWVIDETQEIIDRQTERYKKILEDEYNEAMSXXXXXXXXXXXXXXXXXXXQWLHIYGLVPQHMTILDALAPTIVKVRPKYVPIIDKYVMSKVFEEILPISHVVTEGSPKRGYKPVVRLVNPLAVDLKAYQEKLENLMNKYRKKLRKLIQIHIGDSTLNAFDEMLVKYPLGNDDVKRWVMKAFRDANWPMGEEELEMFMNEIYIGQKYFIQAGDLLRIRGKTGPGKGGKDETPEFEPFDGELQNTNEPFSKVLLAAMKGATILAPGPEDGYYYDAQIINWPNCDFVDVQFNMFAGITSVPVPDCVILPEKYARITAGMTALIKVYNMDNDRTFYLPGIITSSKIVHPGLNEERYHVTLYNGLESTVRPDEVVAISKENYDRIIKNIEDKVANDYTGANATSMSASIVTYSDSRKKNLSTAADITNMXXXXXXXXXXXXXXGFELASATKSASKILKKASNRSLSNESKSAPRSEQQIRPKIPKYSNLSCAQIDIGDQHIPADLAQKLVIPQNQSQTIGYPNRPLISVNDLVLEENILVSQNYENQENPDVKQISPLSKENANRSQTSQLGYASENVMKDIKKQSGVIKSDMETEKNVINVDPVSEKTLEDNFMENALQGKGYSVFTENYKIKGSVTPESKVYXXXXXXXXXXXXXXXTSPLSTGEGTTPILLAEQFQYPYANVKNQDRHKKPESREEKEVGLAAQNNISKGVTVPLPNIQNQILSSHLSPDNQGLKGDPKSFEDNIMKAPKQISQIGIVEKSKSHSNEINDYSKPILDKADASPSKVVIQSEYEKRGEDNLXXXXXXXXXXXXXXGKRDSKKQDSGSLMCSPKDFCSKATKTKEKDKPSRNSLERKDSPKSNILADKNVSIYVQEGSKYVGSESSLKEYEGFADFDKQSKLDSSFNETKMTSQXXXXXXXXXXXXTQGNDALDVKSKEFMLPSESRKSEDQIPDPSIDK------------------KSKASKPPK-------------------------TQGNDALGIASKEIKSSIEYRRLESQVPTSSIEKKTKVLKPPKPQENDTFGIMSKEFKSSAESRNSEDQVXXXXXXXXXXXXXXXXXXXRAEIKNVNDRKEMLANEIGPKVVIENYDLPENDKIIQTXXXXXXXXXXXXXXXXICTDVCLKEKDVSQSSGSVVPRPADVEILQNDHYGVYNIILTPTTSIVFPQTHPGCKTFEIANVSLTVREIPGTLMSSITKDVKSLPAIAEIHKTYSYSSDELCKNCKLPKVPFGPDASHKLQRSKSS 6386
MYEMKNTPNVQISPTFDLPKKNIVSTIKRTDAVIVPEIDMKLYPTKVWNPDAKLQVSSEQWLNKFGLKASNLDSSSLYPRLGFARLEGFNDVLKKPIHSRYGDNLFPKHFREDGLTFNVVAKKEKLLQVQQELENAVQLYQQRLEWLSSESRRLFGVIEEHCVTIIIDIKNKNKRDFDQFICAIERFLNEQIRCIAKFNLIRVQENKCQLSNNLLPVSKDNLANGIDWLWQIDRTSATNSANLVEALIRASNNKENEALYLITEDLSSDGSREVLREKVKQLKIPLNIISYNCKDPEFISYLKCLVLMTGGRFHSYLFNLEVDAYESSPLDSENPKANLLLKKKVYGGSIGGIGTRNDCVAVFSEIEEAKALINQIKSLINQIPEKKGIYD DNSQSKLAVHIPREEYMSSQEWLAKYGLKSRKLDFFDVLSGVCFRHCDGVVDVLEPPPVDKLDFMEQQNATLHQKLINAKYCDKFAHVKWKDGSLVHVQMSSDVHRLYSERMKLCLLAITRRIEWLRQGSRELFGTIMEDQVYILIDISASMEPHISFVKDKLYTLIQEQLRHKSKINFVAFNTKALPWRDRLVDVTEANLKSAWQWLEGLTCQGSTNTLSALQFAIKDRNCQGIYLLTDGRPDQPTKTVLSQIRLQYRLPIHTISFNCADLEANTFLCELARETGGRFHYFNEISGGADCTNENELEAWESEDIKLLKSEYRLGFDSLEKVTKLRDECHKLAWKSEVVRKKEQKSTRKTMAPGCNQNPYFSQISPSRPKCENREIKYPRPIKAKNTFRKQQKEQENDPIWSGTIKLLNLDSTTVASQSDAYQSFLEALSSRDENEQEWVIDETQEIIDRQTERYKKILEDEYNEAMSKKQPNIKKDKPKQKDLTLKQWLHIYGLVPQHMTILDALAPTIVKVRPKYVPIIDKYVMSKVFEEILPISHVVTEGSPKRGYKPVVRLVNPLAVDLKAYQEKLENLMNKYRKKLRKLIQIHIGDSTLNAFDEMLVKYPL EELEMFMNEIYIGQKYFIQAGDLLRIRGKTGPGKGGKDETPEFEPFDGELQNTNEPFSKVLLAAMKGATILAPGPEDGYYYDAQIINWPNCDFVDVQFNMFAGITSVPVPDCVILPEKYARITAGMTALIKVYNMDNDRTFYLPGIITSSKIVHPGLNEERYHVTLYNGLESTVRPDEVVAISKENYDRIIKNIEDKVANDYTGANATSMSASIVTYSDSRKKNLSTAADITNMKSTSK STPKKRKKGFELASATKSASKILKKASNRSLSNESKSAPRSEQQIRPKIPKYSNLSCAQIDIGDQ IPADLAQKLVIPQNQSQTIGYPNRPLISVNDLVLEENILVSQNYENQENPDVKQISPLSKENANRSQTSQLGYASENVMKDIKKQSGV+KSDMETEKNVINVDPVSEKTLEDNFMENALQGKGYSVFTENYKIKGSVTPESKVYKSKLGKSEKLESRLKTSPLSTGEGTTPILLAEQFQYPYANVKNQDRHKKPESREEKEVGLAAQNNISKGVTVPLPNIQNQILSSHLSPDNQGLKGDPKSFEDNIMK PKQISQIGIVEKSKSHSNEINDYSKPILDKADASPSKVVIQSEYEKRGEDNLEN+EKEHQIEEEIEGKRDSKKQDSGSLMCSPKDFCSKATKTKEKDKPSRNSLERKDSPKSNILADKNVSIYVQEGSKYVGSESS KEYEGFADFDKQSKLDSSFNETKMTSQLL KAKAKHLPKTQGNDALDVKSKEFMLPSESRKSEDQIPDPSIDK KSK P TQGNDALGIASKEIKSSIEYRRLESQVP SSIEKKTKVLKPPKPQENDTFGIMSKEFKSSAESRNSEDQVSDSPIDKKTSKPSKKHHKKRAEIKNVNDRKEMLANEIGPKVVI+NYDLPENDKIIQTKAKEHHEKKKDKSKKSICTDVCLKEKDVSQSSGSVVPRPADVEILQNDHYGVYNIILTPTTSIVFPQTHP CKTFEIANVSLTVREIPGTLMSSITKDVKSLPAIAEIHKTYSYSSDELCKNCKLPKVPFGPDASHKLQRSKSS
Sbjct: 1 MYEMKNTPNVQISPTFDLPKKNIVSTIKRTDAVIVPEIDMKLYPTKVWNPDAKLQVSSEQWLNKFGLKASNLDSSSLYPRLGFARLEGFNDVLKKPIHSRYGDNLFPKHFREDGLTFNVVAKKEKLLQVQQELENAVQLYQQRLEWLSSESRRLFGVIEEHCVTIIIDIKNKNKRDFDQFICAIERFLNEQIRCIAKFNLIRVQENKCQLSNNLLPVSKDNLANGIDWLWQIDRTSATNSANLVEALIRASNNKENEALYLITEDLSSDGSREVLREKVKQLKIPLNIISYNCKDPEFISYLKCLVLMTGGRFHSYLFNLEVDAYESSPLDSENPKANLLLKKKVYGGSIGGIGTRNDCVAVFSEIEEAKALINQIKSLINQIPEKKGIYD--------------------------------------DNSQSKLAVHIPREEYMSSQEWLAKYGLKSRKLDFFDVLSGVCFRHCDGVVDVLEPPPVDKLDFMEQQNATLHQKLINAKYCDKFAHVKWKDGSLVHVQMSSDVHRLYSERMKLCLLAITRRIEWLRQGSRELFGTIMEDQVYILIDISASMEPHISFVKDKLYTLIQEQLRHKSKINFVAFNTKALPWRDRLVDVTEANLKSAWQWLEGLTCQGSTNTLSALQFAIKDRNCQGIYLLTDGRPDQPTKTVLSQIRLQYRLPIHTISFNCADLEANTFLCELARETGGRFHYFNEISGGADCTNENELEAWESEDIKLLKSEYRLGFDSLEKVTKLRDECHKLAWKSEVVRKKEQKSTRKTMAPGCNQNPYFSQISPSRPKCENREIKYPRPIKAKNTFRKQQKEQENDPIWSGTIKLLNLDSTTVASQSDAYQSFLEALSSRDENEQEWVIDETQEIIDRQTERYKKILEDEYNEAMSKKQPNIKKDKPKQKDLTLKQWLHIYGLVPQHMTILDALAPTIVKVRPKYVPIIDKYVMSKVFEEILPISHVVTEGSPKRGYKPVVRLVNPLAVDLKAYQEKLENLMNKYRKKLRKLIQIHIGDSTLNAFDEMLVKYPL----------------------EELEMFMNEIYIGQKYFIQAGDLLRIRGKTGPGKGGKDETPEFEPFDGELQNTNEPFSKVLLAAMKGATILAPGPEDGYYYDAQIINWPNCDFVDVQFNMFAGITSVPVPDCVILPEKYARITAGMTALIKVYNMDNDRTFYLPGIITSSKIVHPGLNEERYHVTLYNGLESTVRPDEVVAISKENYDRIIKNIEDKVANDYTGANATSMSASIVTYSDSRKKNLSTAADITNMKSTSKLSTPKKRKKGFELASATKSASKILKKASNRSLSNESKSAPRSEQQIRPKIPKYSNLSCAQIDIGDQQIPADLAQKLVIPQNQSQTIGYPNRPLISVNDLVLEENILVSQNYENQENPDVKQISPLSKENANRSQTSQLGYASENVMKDIKKQSGVMKSDMETEKNVINVDPVSEKTLEDNFMENALQGKGYSVFTENYKIKGSVTPESKVYKSKLGKSEKLESRLKTSPLSTGEGTTPILLAEQFQYPYANVKNQDRHKKPESREEKEVGLAAQNNISKGVTVPLPNIQNQILSSHLSPDNQGLKGDPKSFEDNIMKTPKQISQIGIVEKSKSHSNEINDYSKPILDKADASPSKVVIQSEYEKRGEDNLENVEKEHQIEEEIEGKRDSKKQDSGSLMCSPKDFCSKATKTKEKDKPSRNSLERKDSPKSNILADKNVSIYVQEGSKYVGSESSPKEYEGFADFDKQSKLDSSFNETKMTSQLLAKAKAKHLPKTQGNDALDVKSKEFMLPSESRKSEDQIPDPSIDKKSKASKPPKTQGNDALDVKSKEFMLPSESRKSDDQIPDPSIDKKSKASKPPKTQGNDALGIASKEIKSSIEYRRLESQVPASSIEKKTKVLKPPKPQENDTFGIMSKEFKSSAESRNSEDQVSDSPIDKKTSKPSKKHHKKRAEIKNVNDRKEMLANEIGPKVVIDNYDLPENDKIIQTKAKEHHEKKKDKSKKSICTDVCLKEKDVSQSSGSVVPRPADVEILQNDHYGVYNIILTPTTSIVFPQTHPVCKTFEIANVSLTVREIPGTLMSSITKDVKSLPAIAEIHKTYSYSSDELCKNCKLPKVPFGPDASHKLQRSKSS 2097
BLAST of von Willebrand factor A domain containing 3B vs. Planmine SMEST
Match: SMESG000047774.1 (SMESG000047774.1) HSP 1 Score: 3835.42 bits (9945), Expect = 0.000e+0 Identity = 2036/2154 (94.52%), Postives = 2039/2154 (94.66%), Query Frame = 3
Query: 54 MKNTPNVQISPTFDLPKKNIVSTIKRTDAVIVPEIDMKLYPTKVWNPDAKLQVSSEQWLNKFGLKASNLDSSSLYPRLGFARLEGFNDVLKKPIHSRYGDNLFPKHFREDGLTFNVVAKKEKLLQVQQELENAVQLYQQRLEWLSSESRRLFGVIEEHCVTXXXXXXXXXXRDFDQFICAIERFLNEQIRCIAKFNLIRVQENKCQLSNNLLPVSKDNLANGIDWLWQIDRTSATNSANLVEALIRASNNKENEALYLITEDLSSDGSREVLREKVKQLKIPLNIISYNCKDPEFISYLKCLVLMTGGRFHSYLFNLEVDAYESSPLDSENPKANLLLKKKVYGGSIGGIGTRNDCVAVFSEIEEAKALINQIKSLINQIPEKKGIYDNHYHHKHPLRVWNHAYGQKEWESCCSYKKPHPCRYCVDDNSQSKLAVHIPREEYMSSQEWLAKYGLKSRKLDFFDVLSGVCFRHCDGVVDVLEPPPVDKLDFMEQQNATLHQKLINAKYCDKFAHVKWKDGSLVHVQMSSDVHRLYSERMKLCLLAITRRIEWLRQGSRELFGTIMEDQVYILIDISASMEPHISFVKDKLYTLIQEQLRHKSKINFVAFNTKALPWRDRLVDVTEANLKSAWQWLEGLTCQGSTNTLSALQFAIKDRNCQGIYLLTDGRPDQPTKTVLSQIRLQYRLPIHTISFNCADLEANTFLCELARETGGRFHYFNEISGGADCTNENELEAWESEDIKLLKSEYRLGFDSLEKVTKLRDECHKLAWKSEVVRKKEQKSTRKTMAPGCNQNPYFSQISPSRPKCENREIKYPRPIKAKNTFRKQQKEQENDPIWSGTIKLLNLDSTTVASQSDAYQSFLEALSSRDENEQEWVIDETQEIIDRQTERYKKILEDEYNEAMSXXXXXXXXXXXXXXXXXXXQWLHIYGLVPQHMTILDALAPTIVKVRPKYVPIIDKYVMSKVFEEILPISHVVTEGSPKRGYKPVVRLVNPLAVDLKAYQEKLENLMNKYRKKLRKLIQIHIGDSTLNAFDEMLVKYPLGNDDVKRWVMKAFRDANWPMGEEELEMFMNEIYIGQKYFIQAGDLLRIRGKTGPGKGGKDETPEFEPFDGELQNTNEPFSKVLLAAMKGATILAPGPEDGYYYDAQIINWPNCDFVDVQFNMFAGITSVPVPDCVILPEKYARITAGMTALIKVYNMDNDRTFYLPGIITSSKIVHPGLNEERYHVTLYNGLESTVRPDEVVAISKENYDRIIKNIEDKVANDYTGANATSMSASIVTYSDSRKKNLSTAADITNMXXXXXXXXXXXXXXGFELASATKSASKILKKASNRSLSNESKSAPRSEQQIRPKIPKYSNLSCAQIDIGDQHIPADLAQKLVIPQNQSQTIGYPNRPLISVNDLVLEENILVSQNYENQENPDVKQISPLSKENANRSQTSQLGYASENVMKDIKKQSGVIKSDMETEKNVINVDPVSEKTLEDNFMENALQGKGYSVFTENYKIKGSVTPESKVYXXXXXXXXXXXXXXXTSPLSTGEGTTPILLAEQFQYPYANVKNQDRHKKPESREEKEVGLAAQNNISKGVTVPLPNIQNQILSSHLSPDNQGLKGDPKSFEDNIMKAPKQISQIGIVEKSKSHSNEINDYSKPILDKADASPSKVVIQSEYEKRGEDNLXXXXXXXXXXXXXXGKRDSKKQDSGSLMCSPKDFCSKATKTKEKDKPSRNSLERKDSPKSNILADKNVSIYVQEGSKYVGSESSLKEYEGFADFDKQSKLDSSFNETKMTSQXXXXXXXXXXXXTQGNDALDVKSKEFMLPSESRKSEDQIPDPSIDK------------------KSKASKPPK-------------------------TQGNDALGIASKEIKSSIEYRRLESQVPTSSIEKKTKVLKPPKPQENDTFGIMSKEFKSSAESRNSEDQVXXXXXXXXXXXXXXXXXXXRAEIKNVNDRKEMLANEIGPKVVIENYDLPENDKIIQTXXXXXXXXXXXXXXXXICTDVCLKEKDVSQSSGSVVPRPADVEILQNDHYGVYNIILTPTTSIVFPQTHPGCKTFEIANVSLTVREIPGTLMSSITKDVKSLPAIAEIHKTYSYSSDELCKNCKLPKVPFGPDASHKLQRSKSS 6386
MKNTPNVQISPTFDLPKKNIVSTIKRTDAVIVPEIDMKLYPTKVWNPDAKLQVSSEQWLNKFGLKASNLDSSSLYPRLGFARLEGFNDVLKKPIHSRYGDNLFPKHFREDGLTFNVVAKKEKLLQVQQELENAVQLYQQRLEWLSSESRRLFGVIEEHCVTIIIDIKNKNKRDFDQFICAIERFLNEQIRCIAKFNLIRVQENKCQLSNNLLPVSKDNLANGIDWLWQIDRTSATNSANLVEALIRASNNKENEALYLITEDLSSDGSREVLREKVKQLKIPLNIISYNCKDPEFISYLKCLVLMTGGRFHSYLFNLEVDAYESSPLDSENPKANLLLKKKVYGGSIGGIGTRNDCVAVFSEIEEAKALINQIKSLINQIPEKKGIYD DNSQSKLAVHIPREEYMSSQEWLAKYGLKSRKLDFFDVLSGVCFRHCDGVVDVLEPPPVDKLDFMEQQNATLHQKLINAKYCDKFAHVKWKDGSLVHVQMSSDVHRLYSERMKLCLLAITRRIEWLRQGSRELFGTIMEDQVYILIDISASMEPHISFVKDKLYTLIQEQLRHKSKINFVAFNTKALPWRDRLVDVTEANLKSAWQWLEGLTCQGSTNTLSALQFAIKDRNCQGIYLLTDGRPDQPTKTVLSQIRLQYRLPIHTISFNCADLEANTFLCELARETGGRFHYFNEISGGADCTNENELEAWESEDIKLLKSEYRLGFDSLEKVTKLRDECHKLAWKSEVVRKKEQKSTRKTMAPGCNQNPYFSQISPSRPKCENREIKYPRPIKAKNTFRKQQKEQENDPIWSGTIKLLNLDSTTVASQSDAYQSFLEALSSRDENEQEWVIDETQEIIDRQTERYKKILEDEYNEAMSKKQPNIKKDKPKQKDLTLKQWLHIYGLVPQHMTILDALAPTIVKVRPKYVPIIDKYVMSKVFEEILPISHVVTEGSPKRGYKPVVRLVNPLAVDLKAYQEKLENLMNKYRKKLRKLIQIHIGDSTLNAFDEMLVKYPL EELEMFMNEIYIGQKYFIQAGDLLRIRGKTGPGKGGKDETPEFEPFDGELQNTNEPFSKVLLAAMKGATILAPGPEDGYYYDAQIINWPNCDFVDVQFNMFAGITSVPVPDCVILPEKYARITAGMTALIKVYNMDNDRTFYLPGIITSSKIVHPGLNEERYHVTLYNGLESTVRPDEVVAISKENYDRIIKNIEDKVANDYTGANATSMSASIVTYSDSRKKNLSTAADITNMKSTSK STPKKRKKGFELASATKSASKILKKASNRSLSNESKSAPRSEQQIRPKIPKYSNLSCAQIDIGDQ IPADLAQKLVIPQNQSQTIGYPNRPLISVNDLVLEENILVSQNYENQENPDVKQISPLSKENANRSQTSQLGYASENVMKDIKKQSGV+KSDMETEKNVINVDPVSEKTLEDNFMENALQGKGYSVFTENYKIKGSVTPESKVYKSKLGKSEKLESRLKTSPLSTGEGTTPILLAEQFQYPYANVKNQDRHKKPESREEKEVGLAAQNNISKGVTVPLPNIQNQILSSHLSPDNQGLKGDPKSFEDNIMK PKQISQIGIVEKSKSHSNEINDYSKPILDKADASPSKVVIQSEYEKRGEDNLEN+EKEHQIEEEIEGKRDSKKQDSGSLMCSPKDFCSKATKTKEKDKPSRNSLERKDSPKSNILADKNVSIYVQEGSKYVGSESS KEYEGFADFDKQSKLDSSFNETKMTSQLL KAKAKHLPKTQGNDALDVKSKEFMLPSESRKSEDQIPDPSIDK KSK P TQGNDALGIASKEIKSSIEYRRLESQVP SSIEKKTKVLKPPKPQENDTFGIMSKEFKSSAESRNSEDQVSDSPIDKKTSKPSKKHHKKRAEIKNVNDRKEMLANEIGPKVVI+NYDLPENDKIIQTKAKEHHEKKKDKSKKSICTDVCLKEKDVSQSSGSVVPRPADVEILQNDHYGVYNIILTPTTSIVFPQTHP CKTFEIANVSLTVREIPGTLMSSITKDVKSLPAIAEIHKTYSYSSDELCKNCKLPKVPFGPDASHKLQRSKSS
Sbjct: 1 MKNTPNVQISPTFDLPKKNIVSTIKRTDAVIVPEIDMKLYPTKVWNPDAKLQVSSEQWLNKFGLKASNLDSSSLYPRLGFARLEGFNDVLKKPIHSRYGDNLFPKHFREDGLTFNVVAKKEKLLQVQQELENAVQLYQQRLEWLSSESRRLFGVIEEHCVTIIIDIKNKNKRDFDQFICAIERFLNEQIRCIAKFNLIRVQENKCQLSNNLLPVSKDNLANGIDWLWQIDRTSATNSANLVEALIRASNNKENEALYLITEDLSSDGSREVLREKVKQLKIPLNIISYNCKDPEFISYLKCLVLMTGGRFHSYLFNLEVDAYESSPLDSENPKANLLLKKKVYGGSIGGIGTRNDCVAVFSEIEEAKALINQIKSLINQIPEKKGIYD--------------------------------------DNSQSKLAVHIPREEYMSSQEWLAKYGLKSRKLDFFDVLSGVCFRHCDGVVDVLEPPPVDKLDFMEQQNATLHQKLINAKYCDKFAHVKWKDGSLVHVQMSSDVHRLYSERMKLCLLAITRRIEWLRQGSRELFGTIMEDQVYILIDISASMEPHISFVKDKLYTLIQEQLRHKSKINFVAFNTKALPWRDRLVDVTEANLKSAWQWLEGLTCQGSTNTLSALQFAIKDRNCQGIYLLTDGRPDQPTKTVLSQIRLQYRLPIHTISFNCADLEANTFLCELARETGGRFHYFNEISGGADCTNENELEAWESEDIKLLKSEYRLGFDSLEKVTKLRDECHKLAWKSEVVRKKEQKSTRKTMAPGCNQNPYFSQISPSRPKCENREIKYPRPIKAKNTFRKQQKEQENDPIWSGTIKLLNLDSTTVASQSDAYQSFLEALSSRDENEQEWVIDETQEIIDRQTERYKKILEDEYNEAMSKKQPNIKKDKPKQKDLTLKQWLHIYGLVPQHMTILDALAPTIVKVRPKYVPIIDKYVMSKVFEEILPISHVVTEGSPKRGYKPVVRLVNPLAVDLKAYQEKLENLMNKYRKKLRKLIQIHIGDSTLNAFDEMLVKYPL----------------------EELEMFMNEIYIGQKYFIQAGDLLRIRGKTGPGKGGKDETPEFEPFDGELQNTNEPFSKVLLAAMKGATILAPGPEDGYYYDAQIINWPNCDFVDVQFNMFAGITSVPVPDCVILPEKYARITAGMTALIKVYNMDNDRTFYLPGIITSSKIVHPGLNEERYHVTLYNGLESTVRPDEVVAISKENYDRIIKNIEDKVANDYTGANATSMSASIVTYSDSRKKNLSTAADITNMKSTSKLSTPKKRKKGFELASATKSASKILKKASNRSLSNESKSAPRSEQQIRPKIPKYSNLSCAQIDIGDQQIPADLAQKLVIPQNQSQTIGYPNRPLISVNDLVLEENILVSQNYENQENPDVKQISPLSKENANRSQTSQLGYASENVMKDIKKQSGVMKSDMETEKNVINVDPVSEKTLEDNFMENALQGKGYSVFTENYKIKGSVTPESKVYKSKLGKSEKLESRLKTSPLSTGEGTTPILLAEQFQYPYANVKNQDRHKKPESREEKEVGLAAQNNISKGVTVPLPNIQNQILSSHLSPDNQGLKGDPKSFEDNIMKTPKQISQIGIVEKSKSHSNEINDYSKPILDKADASPSKVVIQSEYEKRGEDNLENVEKEHQIEEEIEGKRDSKKQDSGSLMCSPKDFCSKATKTKEKDKPSRNSLERKDSPKSNILADKNVSIYVQEGSKYVGSESSPKEYEGFADFDKQSKLDSSFNETKMTSQLLAKAKAKHLPKTQGNDALDVKSKEFMLPSESRKSEDQIPDPSIDKKSKASKPPKTQGNDALDVKSKEFMLPSESRKSDDQIPDPSIDKKSKASKPPKTQGNDALGIASKEIKSSIEYRRLESQVPASSIEKKTKVLKPPKPQENDTFGIMSKEFKSSAESRNSEDQVSDSPIDKKTSKPSKKHHKKRAEIKNVNDRKEMLANEIGPKVVIDNYDLPENDKIIQTKAKEHHEKKKDKSKKSICTDVCLKEKDVSQSSGSVVPRPADVEILQNDHYGVYNIILTPTTSIVFPQTHPVCKTFEIANVSLTVREIPGTLMSSITKDVKSLPAIAEIHKTYSYSSDELCKNCKLPKVPFGPDASHKLQRSKSS 2094
BLAST of von Willebrand factor A domain containing 3B vs. Planmine SMEST
Match: SMESG000047774.1 (SMESG000047774.1) HSP 1 Score: 2140.93 bits (5546), Expect = 0.000e+0 Identity = 1064/1064 (100.00%), Postives = 1064/1064 (100.00%), Query Frame = 3
Query: 45 MYEMKNTPNVQISPTFDLPKKNIVSTIKRTDAVIVPEIDMKLYPTKVWNPDAKLQVSSEQWLNKFGLKASNLDSSSLYPRLGFARLEGFNDVLKKPIHSRYGDNLFPKHFREDGLTFNVVAKKEKLLQVQQELENAVQLYQQRLEWLSSESRRLFGVIEEHCVTXXXXXXXXXXRDFDQFICAIERFLNEQIRCIAKFNLIRVQENKCQLSNNLLPVSKDNLANGIDWLWQIDRTSATNSANLVEALIRASNNKENEALYLITEDLSSDGSREVLREKVKQLKIPLNIISYNCKDPEFISYLKCLVLMTGGRFHSYLFNLEVDAYESSPLDSENPKANLLLKKKVYGGSIGGIGTRNDCVAVFSEIEEAKALINQIKSLINQIPEKKGIYDNHYHHKHPLRVWNHAYGQKEWESCCSYKKPHPCRYCVDDNSQSKLAVHIPREEYMSSQEWLAKYGLKSRKLDFFDVLSGVCFRHCDGVVDVLEPPPVDKLDFMEQQNATLHQKLINAKYCDKFAHVKWKDGSLVHVQMSSDVHRLYSERMKLCLLAITRRIEWLRQGSRELFGTIMEDQVYILIDISASMEPHISFVKDKLYTLIQEQLRHKSKINFVAFNTKALPWRDRLVDVTEANLKSAWQWLEGLTCQGSTNTLSALQFAIKDRNCQGIYLLTDGRPDQPTKTVLSQIRLQYRLPIHTISFNCADLEANTFLCELARETGGRFHYFNEISGGADCTNENELEAWESEDIKLLKSEYRLGFDSLEKVTKLRDECHKLAWKSEVVRKKEQKSTRKTMAPGCNQNPYFSQISPSRPKCENREIKYPRPIKAKNTFRKQQKEQENDPIWSGTIKLLNLDSTTVASQSDAYQSFLEALSSRDENEQEWVIDETQEIIDRQTERYKKILEDEYNEAMSXXXXXXXXXXXXXXXXXXXQWLHIYGLVPQHMTILDALAPTIVKVRPKYVPIIDKYVMSKVFEEILPISHVVTEGSPKRGYKPVVRLVNPLAVDLKAYQEKLENLMNKYRKKLRKLIQIHIGDSTLNAFDEMLVKYPLGNDDVKRWVMKAFRDANWP 3236
MYEMKNTPNVQISPTFDLPKKNIVSTIKRTDAVIVPEIDMKLYPTKVWNPDAKLQVSSEQWLNKFGLKASNLDSSSLYPRLGFARLEGFNDVLKKPIHSRYGDNLFPKHFREDGLTFNVVAKKEKLLQVQQELENAVQLYQQRLEWLSSESRRLFGVIEEHCVTIIIDIKNKNKRDFDQFICAIERFLNEQIRCIAKFNLIRVQENKCQLSNNLLPVSKDNLANGIDWLWQIDRTSATNSANLVEALIRASNNKENEALYLITEDLSSDGSREVLREKVKQLKIPLNIISYNCKDPEFISYLKCLVLMTGGRFHSYLFNLEVDAYESSPLDSENPKANLLLKKKVYGGSIGGIGTRNDCVAVFSEIEEAKALINQIKSLINQIPEKKGIYDNHYHHKHPLRVWNHAYGQKEWESCCSYKKPHPCRYCVDDNSQSKLAVHIPREEYMSSQEWLAKYGLKSRKLDFFDVLSGVCFRHCDGVVDVLEPPPVDKLDFMEQQNATLHQKLINAKYCDKFAHVKWKDGSLVHVQMSSDVHRLYSERMKLCLLAITRRIEWLRQGSRELFGTIMEDQVYILIDISASMEPHISFVKDKLYTLIQEQLRHKSKINFVAFNTKALPWRDRLVDVTEANLKSAWQWLEGLTCQGSTNTLSALQFAIKDRNCQGIYLLTDGRPDQPTKTVLSQIRLQYRLPIHTISFNCADLEANTFLCELARETGGRFHYFNEISGGADCTNENELEAWESEDIKLLKSEYRLGFDSLEKVTKLRDECHKLAWKSEVVRKKEQKSTRKTMAPGCNQNPYFSQISPSRPKCENREIKYPRPIKAKNTFRKQQKEQENDPIWSGTIKLLNLDSTTVASQSDAYQSFLEALSSRDENEQEWVIDETQEIIDRQTERYKKILEDEYNEAMSKKQPNIKKDKPKQKDLTLKQWLHIYGLVPQHMTILDALAPTIVKVRPKYVPIIDKYVMSKVFEEILPISHVVTEGSPKRGYKPVVRLVNPLAVDLKAYQEKLENLMNKYRKKLRKLIQIHIGDSTLNAFDEMLVKYPLGNDDVKRWVMKAFRDANWP
Sbjct: 1 MYEMKNTPNVQISPTFDLPKKNIVSTIKRTDAVIVPEIDMKLYPTKVWNPDAKLQVSSEQWLNKFGLKASNLDSSSLYPRLGFARLEGFNDVLKKPIHSRYGDNLFPKHFREDGLTFNVVAKKEKLLQVQQELENAVQLYQQRLEWLSSESRRLFGVIEEHCVTIIIDIKNKNKRDFDQFICAIERFLNEQIRCIAKFNLIRVQENKCQLSNNLLPVSKDNLANGIDWLWQIDRTSATNSANLVEALIRASNNKENEALYLITEDLSSDGSREVLREKVKQLKIPLNIISYNCKDPEFISYLKCLVLMTGGRFHSYLFNLEVDAYESSPLDSENPKANLLLKKKVYGGSIGGIGTRNDCVAVFSEIEEAKALINQIKSLINQIPEKKGIYDNHYHHKHPLRVWNHAYGQKEWESCCSYKKPHPCRYCVDDNSQSKLAVHIPREEYMSSQEWLAKYGLKSRKLDFFDVLSGVCFRHCDGVVDVLEPPPVDKLDFMEQQNATLHQKLINAKYCDKFAHVKWKDGSLVHVQMSSDVHRLYSERMKLCLLAITRRIEWLRQGSRELFGTIMEDQVYILIDISASMEPHISFVKDKLYTLIQEQLRHKSKINFVAFNTKALPWRDRLVDVTEANLKSAWQWLEGLTCQGSTNTLSALQFAIKDRNCQGIYLLTDGRPDQPTKTVLSQIRLQYRLPIHTISFNCADLEANTFLCELARETGGRFHYFNEISGGADCTNENELEAWESEDIKLLKSEYRLGFDSLEKVTKLRDECHKLAWKSEVVRKKEQKSTRKTMAPGCNQNPYFSQISPSRPKCENREIKYPRPIKAKNTFRKQQKEQENDPIWSGTIKLLNLDSTTVASQSDAYQSFLEALSSRDENEQEWVIDETQEIIDRQTERYKKILEDEYNEAMSKKQPNIKKDKPKQKDLTLKQWLHIYGLVPQHMTILDALAPTIVKVRPKYVPIIDKYVMSKVFEEILPISHVVTEGSPKRGYKPVVRLVNPLAVDLKAYQEKLENLMNKYRKKLRKLIQIHIGDSTLNAFDEMLVKYPLGNDDVKRWVMKAFRDANWP 1064
BLAST of von Willebrand factor A domain containing 3B vs. Planmine SMEST
Match: SMESG000047774.1 (SMESG000047774.1) HSP 1 Score: 2133.99 bits (5528), Expect = 0.000e+0 Identity = 1061/1061 (100.00%), Postives = 1061/1061 (100.00%), Query Frame = 3
Query: 54 MKNTPNVQISPTFDLPKKNIVSTIKRTDAVIVPEIDMKLYPTKVWNPDAKLQVSSEQWLNKFGLKASNLDSSSLYPRLGFARLEGFNDVLKKPIHSRYGDNLFPKHFREDGLTFNVVAKKEKLLQVQQELENAVQLYQQRLEWLSSESRRLFGVIEEHCVTXXXXXXXXXXRDFDQFICAIERFLNEQIRCIAKFNLIRVQENKCQLSNNLLPVSKDNLANGIDWLWQIDRTSATNSANLVEALIRASNNKENEALYLITEDLSSDGSREVLREKVKQLKIPLNIISYNCKDPEFISYLKCLVLMTGGRFHSYLFNLEVDAYESSPLDSENPKANLLLKKKVYGGSIGGIGTRNDCVAVFSEIEEAKALINQIKSLINQIPEKKGIYDNHYHHKHPLRVWNHAYGQKEWESCCSYKKPHPCRYCVDDNSQSKLAVHIPREEYMSSQEWLAKYGLKSRKLDFFDVLSGVCFRHCDGVVDVLEPPPVDKLDFMEQQNATLHQKLINAKYCDKFAHVKWKDGSLVHVQMSSDVHRLYSERMKLCLLAITRRIEWLRQGSRELFGTIMEDQVYILIDISASMEPHISFVKDKLYTLIQEQLRHKSKINFVAFNTKALPWRDRLVDVTEANLKSAWQWLEGLTCQGSTNTLSALQFAIKDRNCQGIYLLTDGRPDQPTKTVLSQIRLQYRLPIHTISFNCADLEANTFLCELARETGGRFHYFNEISGGADCTNENELEAWESEDIKLLKSEYRLGFDSLEKVTKLRDECHKLAWKSEVVRKKEQKSTRKTMAPGCNQNPYFSQISPSRPKCENREIKYPRPIKAKNTFRKQQKEQENDPIWSGTIKLLNLDSTTVASQSDAYQSFLEALSSRDENEQEWVIDETQEIIDRQTERYKKILEDEYNEAMSXXXXXXXXXXXXXXXXXXXQWLHIYGLVPQHMTILDALAPTIVKVRPKYVPIIDKYVMSKVFEEILPISHVVTEGSPKRGYKPVVRLVNPLAVDLKAYQEKLENLMNKYRKKLRKLIQIHIGDSTLNAFDEMLVKYPLGNDDVKRWVMKAFRDANWP 3236
MKNTPNVQISPTFDLPKKNIVSTIKRTDAVIVPEIDMKLYPTKVWNPDAKLQVSSEQWLNKFGLKASNLDSSSLYPRLGFARLEGFNDVLKKPIHSRYGDNLFPKHFREDGLTFNVVAKKEKLLQVQQELENAVQLYQQRLEWLSSESRRLFGVIEEHCVTIIIDIKNKNKRDFDQFICAIERFLNEQIRCIAKFNLIRVQENKCQLSNNLLPVSKDNLANGIDWLWQIDRTSATNSANLVEALIRASNNKENEALYLITEDLSSDGSREVLREKVKQLKIPLNIISYNCKDPEFISYLKCLVLMTGGRFHSYLFNLEVDAYESSPLDSENPKANLLLKKKVYGGSIGGIGTRNDCVAVFSEIEEAKALINQIKSLINQIPEKKGIYDNHYHHKHPLRVWNHAYGQKEWESCCSYKKPHPCRYCVDDNSQSKLAVHIPREEYMSSQEWLAKYGLKSRKLDFFDVLSGVCFRHCDGVVDVLEPPPVDKLDFMEQQNATLHQKLINAKYCDKFAHVKWKDGSLVHVQMSSDVHRLYSERMKLCLLAITRRIEWLRQGSRELFGTIMEDQVYILIDISASMEPHISFVKDKLYTLIQEQLRHKSKINFVAFNTKALPWRDRLVDVTEANLKSAWQWLEGLTCQGSTNTLSALQFAIKDRNCQGIYLLTDGRPDQPTKTVLSQIRLQYRLPIHTISFNCADLEANTFLCELARETGGRFHYFNEISGGADCTNENELEAWESEDIKLLKSEYRLGFDSLEKVTKLRDECHKLAWKSEVVRKKEQKSTRKTMAPGCNQNPYFSQISPSRPKCENREIKYPRPIKAKNTFRKQQKEQENDPIWSGTIKLLNLDSTTVASQSDAYQSFLEALSSRDENEQEWVIDETQEIIDRQTERYKKILEDEYNEAMSKKQPNIKKDKPKQKDLTLKQWLHIYGLVPQHMTILDALAPTIVKVRPKYVPIIDKYVMSKVFEEILPISHVVTEGSPKRGYKPVVRLVNPLAVDLKAYQEKLENLMNKYRKKLRKLIQIHIGDSTLNAFDEMLVKYPLGNDDVKRWVMKAFRDANWP
Sbjct: 1 MKNTPNVQISPTFDLPKKNIVSTIKRTDAVIVPEIDMKLYPTKVWNPDAKLQVSSEQWLNKFGLKASNLDSSSLYPRLGFARLEGFNDVLKKPIHSRYGDNLFPKHFREDGLTFNVVAKKEKLLQVQQELENAVQLYQQRLEWLSSESRRLFGVIEEHCVTIIIDIKNKNKRDFDQFICAIERFLNEQIRCIAKFNLIRVQENKCQLSNNLLPVSKDNLANGIDWLWQIDRTSATNSANLVEALIRASNNKENEALYLITEDLSSDGSREVLREKVKQLKIPLNIISYNCKDPEFISYLKCLVLMTGGRFHSYLFNLEVDAYESSPLDSENPKANLLLKKKVYGGSIGGIGTRNDCVAVFSEIEEAKALINQIKSLINQIPEKKGIYDNHYHHKHPLRVWNHAYGQKEWESCCSYKKPHPCRYCVDDNSQSKLAVHIPREEYMSSQEWLAKYGLKSRKLDFFDVLSGVCFRHCDGVVDVLEPPPVDKLDFMEQQNATLHQKLINAKYCDKFAHVKWKDGSLVHVQMSSDVHRLYSERMKLCLLAITRRIEWLRQGSRELFGTIMEDQVYILIDISASMEPHISFVKDKLYTLIQEQLRHKSKINFVAFNTKALPWRDRLVDVTEANLKSAWQWLEGLTCQGSTNTLSALQFAIKDRNCQGIYLLTDGRPDQPTKTVLSQIRLQYRLPIHTISFNCADLEANTFLCELARETGGRFHYFNEISGGADCTNENELEAWESEDIKLLKSEYRLGFDSLEKVTKLRDECHKLAWKSEVVRKKEQKSTRKTMAPGCNQNPYFSQISPSRPKCENREIKYPRPIKAKNTFRKQQKEQENDPIWSGTIKLLNLDSTTVASQSDAYQSFLEALSSRDENEQEWVIDETQEIIDRQTERYKKILEDEYNEAMSKKQPNIKKDKPKQKDLTLKQWLHIYGLVPQHMTILDALAPTIVKVRPKYVPIIDKYVMSKVFEEILPISHVVTEGSPKRGYKPVVRLVNPLAVDLKAYQEKLENLMNKYRKKLRKLIQIHIGDSTLNAFDEMLVKYPLGNDDVKRWVMKAFRDANWP 1061
BLAST of von Willebrand factor A domain containing 3B vs. Planmine SMEST
Match: SMESG000047774.1 (SMESG000047774.1) HSP 1 Score: 2030.37 bits (5259), Expect = 0.000e+0 Identity = 1026/1064 (96.43%), Postives = 1026/1064 (96.43%), Query Frame = 3
Query: 45 MYEMKNTPNVQISPTFDLPKKNIVSTIKRTDAVIVPEIDMKLYPTKVWNPDAKLQVSSEQWLNKFGLKASNLDSSSLYPRLGFARLEGFNDVLKKPIHSRYGDNLFPKHFREDGLTFNVVAKKEKLLQVQQELENAVQLYQQRLEWLSSESRRLFGVIEEHCVTXXXXXXXXXXRDFDQFICAIERFLNEQIRCIAKFNLIRVQENKCQLSNNLLPVSKDNLANGIDWLWQIDRTSATNSANLVEALIRASNNKENEALYLITEDLSSDGSREVLREKVKQLKIPLNIISYNCKDPEFISYLKCLVLMTGGRFHSYLFNLEVDAYESSPLDSENPKANLLLKKKVYGGSIGGIGTRNDCVAVFSEIEEAKALINQIKSLINQIPEKKGIYDNHYHHKHPLRVWNHAYGQKEWESCCSYKKPHPCRYCVDDNSQSKLAVHIPREEYMSSQEWLAKYGLKSRKLDFFDVLSGVCFRHCDGVVDVLEPPPVDKLDFMEQQNATLHQKLINAKYCDKFAHVKWKDGSLVHVQMSSDVHRLYSERMKLCLLAITRRIEWLRQGSRELFGTIMEDQVYILIDISASMEPHISFVKDKLYTLIQEQLRHKSKINFVAFNTKALPWRDRLVDVTEANLKSAWQWLEGLTCQGSTNTLSALQFAIKDRNCQGIYLLTDGRPDQPTKTVLSQIRLQYRLPIHTISFNCADLEANTFLCELARETGGRFHYFNEISGGADCTNENELEAWESEDIKLLKSEYRLGFDSLEKVTKLRDECHKLAWKSEVVRKKEQKSTRKTMAPGCNQNPYFSQISPSRPKCENREIKYPRPIKAKNTFRKQQKEQENDPIWSGTIKLLNLDSTTVASQSDAYQSFLEALSSRDENEQEWVIDETQEIIDRQTERYKKILEDEYNEAMSXXXXXXXXXXXXXXXXXXXQWLHIYGLVPQHMTILDALAPTIVKVRPKYVPIIDKYVMSKVFEEILPISHVVTEGSPKRGYKPVVRLVNPLAVDLKAYQEKLENLMNKYRKKLRKLIQIHIGDSTLNAFDEMLVKYPLGNDDVKRWVMKAFRDANWP 3236
MYEMKNTPNVQISPTFDLPKKNIVSTIKRTDAVIVPEIDMKLYPTKVWNPDAKLQVSSEQWLNKFGLKASNLDSSSLYPRLGFARLEGFNDVLKKPIHSRYGDNLFPKHFREDGLTFNVVAKKEKLLQVQQELENAVQLYQQRLEWLSSESRRLFGVIEEHCVTIIIDIKNKNKRDFDQFICAIERFLNEQIRCIAKFNLIRVQENKCQLSNNLLPVSKDNLANGIDWLWQIDRTSATNSANLVEALIRASNNKENEALYLITEDLSSDGSREVLREKVKQLKIPLNIISYNCKDPEFISYLKCLVLMTGGRFHSYLFNLEVDAYESSPLDSENPKANLLLKKKVYGGSIGGIGTRNDCVAVFSEIEEAKALINQIKSLINQIPEKKGIYD DNSQSKLAVHIPREEYMSSQEWLAKYGLKSRKLDFFDVLSGVCFRHCDGVVDVLEPPPVDKLDFMEQQNATLHQKLINAKYCDKFAHVKWKDGSLVHVQMSSDVHRLYSERMKLCLLAITRRIEWLRQGSRELFGTIMEDQVYILIDISASMEPHISFVKDKLYTLIQEQLRHKSKINFVAFNTKALPWRDRLVDVTEANLKSAWQWLEGLTCQGSTNTLSALQFAIKDRNCQGIYLLTDGRPDQPTKTVLSQIRLQYRLPIHTISFNCADLEANTFLCELARETGGRFHYFNEISGGADCTNENELEAWESEDIKLLKSEYRLGFDSLEKVTKLRDECHKLAWKSEVVRKKEQKSTRKTMAPGCNQNPYFSQISPSRPKCENREIKYPRPIKAKNTFRKQQKEQENDPIWSGTIKLLNLDSTTVASQSDAYQSFLEALSSRDENEQEWVIDETQEIIDRQTERYKKILEDEYNEAMSKKQPNIKKDKPKQKDLTLKQWLHIYGLVPQHMTILDALAPTIVKVRPKYVPIIDKYVMSKVFEEILPISHVVTEGSPKRGYKPVVRLVNPLAVDLKAYQEKLENLMNKYRKKLRKLIQIHIGDSTLNAFDEMLVKYPLGNDDVKRWVMKAFRDANWP
Sbjct: 1 MYEMKNTPNVQISPTFDLPKKNIVSTIKRTDAVIVPEIDMKLYPTKVWNPDAKLQVSSEQWLNKFGLKASNLDSSSLYPRLGFARLEGFNDVLKKPIHSRYGDNLFPKHFREDGLTFNVVAKKEKLLQVQQELENAVQLYQQRLEWLSSESRRLFGVIEEHCVTIIIDIKNKNKRDFDQFICAIERFLNEQIRCIAKFNLIRVQENKCQLSNNLLPVSKDNLANGIDWLWQIDRTSATNSANLVEALIRASNNKENEALYLITEDLSSDGSREVLREKVKQLKIPLNIISYNCKDPEFISYLKCLVLMTGGRFHSYLFNLEVDAYESSPLDSENPKANLLLKKKVYGGSIGGIGTRNDCVAVFSEIEEAKALINQIKSLINQIPEKKGIYD--------------------------------------DNSQSKLAVHIPREEYMSSQEWLAKYGLKSRKLDFFDVLSGVCFRHCDGVVDVLEPPPVDKLDFMEQQNATLHQKLINAKYCDKFAHVKWKDGSLVHVQMSSDVHRLYSERMKLCLLAITRRIEWLRQGSRELFGTIMEDQVYILIDISASMEPHISFVKDKLYTLIQEQLRHKSKINFVAFNTKALPWRDRLVDVTEANLKSAWQWLEGLTCQGSTNTLSALQFAIKDRNCQGIYLLTDGRPDQPTKTVLSQIRLQYRLPIHTISFNCADLEANTFLCELARETGGRFHYFNEISGGADCTNENELEAWESEDIKLLKSEYRLGFDSLEKVTKLRDECHKLAWKSEVVRKKEQKSTRKTMAPGCNQNPYFSQISPSRPKCENREIKYPRPIKAKNTFRKQQKEQENDPIWSGTIKLLNLDSTTVASQSDAYQSFLEALSSRDENEQEWVIDETQEIIDRQTERYKKILEDEYNEAMSKKQPNIKKDKPKQKDLTLKQWLHIYGLVPQHMTILDALAPTIVKVRPKYVPIIDKYVMSKVFEEILPISHVVTEGSPKRGYKPVVRLVNPLAVDLKAYQEKLENLMNKYRKKLRKLIQIHIGDSTLNAFDEMLVKYPLGNDDVKRWVMKAFRDANWP 1026 The following BLAST results are available for this feature:
BLAST of von Willebrand factor A domain containing 3B vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of von Willebrand factor A domain containing 3B vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 0
BLAST of von Willebrand factor A domain containing 3B vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 0
BLAST of von Willebrand factor A domain containing 3B vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 2
BLAST of von Willebrand factor A domain containing 3B vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 4
BLAST of von Willebrand factor A domain containing 3B vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of von Willebrand factor A domain containing 3B vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of von Willebrand factor A domain containing 3B vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of von Willebrand factor A domain containing 3B vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 3
BLAST of von Willebrand factor A domain containing 3B vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 4
BLAST of von Willebrand factor A domain containing 3B vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of von Willebrand factor A domain containing 3B vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 2
BLAST of von Willebrand factor A domain containing 3B vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 0
BLAST of von Willebrand factor A domain containing 3B vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30017387 ID=SMED30017387|Name=von Willebrand factor A domain containing 3B|organism=Schmidtea mediterranea sexual|type=transcript|length=6464bpback to top protein sequence of SMED30017387-orf-1 >SMED30017387-orf-1 ID=SMED30017387-orf-1|Name=SMED30017387-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=2115bp MYEMKNTPNVQISPTFDLPKKNIVSTIKRTDAVIVPEIDMKLYPTKVWNPback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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