Adenylosuccinate lyase

Overview
NameAdenylosuccinate lyase
Smed IDSMED30017371
Length (bp)2714
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Adenylosuccinate lyase (SMED30017371) t-SNE clustered cells

Violin plots show distribution of expression levels for Adenylosuccinate lyase (SMED30017371) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Adenylosuccinate lyase (SMED30017371) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Adenylosuccinate lyase (SMED30017371) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30017371

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 9

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
X1 cellSMED30017371SMESG000014474.1 SmedASXL_007767SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
X2 cellSMED30017371SMESG000014474.1 SmedASXL_007767SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
pharynxSMED30017371SMESG000014474.1 dd_Smed_v4_2280_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
protonephridiaSMED30017371SMESG000014474.1 dd_Smed_v4_2280_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
nervous systemSMED30017371SMESG000014474.1 dd_Smed_v4_2280_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30017371SMESG000014474.1 dd_Smed_v4_2280_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30017371SMESG000014474.1 dd_Smed_v4_2280_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30017371SMESG000014474.1 dd_Smed_v4_2280_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
muscle cellSMED30017371SMESG000014474.1 dd_Smed_v4_2280_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Adenylosuccinate lyase vs. Ensembl Human
Match: ADSL (adenylosuccinate lyase [Source:HGNC Symbol;Acc:HGNC:291])

HSP 1 Score: 310.842 bits (795), Expect = 1.756e-95
Identity = 155/266 (58.27%), Postives = 202/266 (75.94%), Query Frame = 1 
Query: 1423 NQVEELDVLVSAKAGFLHHFLVTGQTYPRKLDFTIXXXXXXXXXXXHKICTDIRILANMKEIEEPFDSDQDGSSAMPYKRNPMRCERICSLARHVMTQCFNPLMTASIQWMERTLDDSANRRICIPEAFLATDGMLMTFDNVSAGLVVYQRMIEQHITAELPFMSTEAILVKMVQMGEDRQVCHEKIKRISQEAAVNVKEYGKGNDFIERLRAEPYFAKIHGDIEEVLNPYNFTGRSAEQVDRFLKTALKPLDK-YKHLFDEKTEL 2217
            ++VE+LD +V+ KAGF   F++TGQTY RK+D  +LS LA L AS+HKICTDIR+LAN+KE+EEPF+  Q GSSAMPYKRNPMR ER CSLARH+MT   +PL TAS+QW ERTLDDSANRRIC+ EAFL  D +L T  N+S GLVVY ++IE+ I  ELPFM+TE I++ MV+ G  RQ CHEKI+ +SQ+AA  VK+ G  ND IER++ + YF+ IH  ++ +L+P +FTGR+++QV RFL+  + PL K Y+ +   K EL
Sbjct:  231 HKVEQLDKMVTEKAGFKRAFIITGQTYTRKVDIEVLSVLASLGASVHKICTDIRLLANLKEMEEPFEKQQIGSSAMPYKRNPMRSERCCSLARHLMTLVMDPLQTASVQWFERTLDDSANRRICLAEAFLTADTILNTLQNISEGLVVYPKVIERRIRQELPFMATENIIMAMVKAGGSRQDCHEKIRVLSQQAASVVKQEGGDNDLIERIQVDAYFSPIHSQLDHLLDPSSFTGRASQQVQRFLEEEVYPLLKPYESVMKVKAEL 496
[Close]
BLAST of Adenylosuccinate lyase vs. Ensembl Human
Match: ADSL (adenylosuccinate lyase [Source:HGNC Symbol;Acc:HGNC:291])

HSP 1 Score: 310.071 bits (793), Expect = 1.970e-95
Identity = 155/266 (58.27%), Postives = 202/266 (75.94%), Query Frame = 1 
Query: 1423 NQVEELDVLVSAKAGFLHHFLVTGQTYPRKLDFTIXXXXXXXXXXXHKICTDIRILANMKEIEEPFDSDQDGSSAMPYKRNPMRCERICSLARHVMTQCFNPLMTASIQWMERTLDDSANRRICIPEAFLATDGMLMTFDNVSAGLVVYQRMIEQHITAELPFMSTEAILVKMVQMGEDRQVCHEKIKRISQEAAVNVKEYGKGNDFIERLRAEPYFAKIHGDIEEVLNPYNFTGRSAEQVDRFLKTALKPLDK-YKHLFDEKTEL 2217
            ++VE+LD +V+ KAGF   F++TGQTY RK+D  +LS LA L AS+HKICTDIR+LAN+KE+EEPF+  Q GSSAMPYKRNPMR ER CSLARH+MT   +PL TAS+QW ERTLDDSANRRIC+ EAFL  D +L T  N+S GLVVY ++IE+ I  ELPFM+TE I++ MV+ G  RQ CHEKI+ +SQ+AA  VK+ G  ND IER++ + YF+ IH  ++ +L+P +FTGR+++QV RFL+  + PL K Y+ +   K EL
Sbjct:  217 HKVEQLDKMVTEKAGFKRAFIITGQTYTRKVDIEVLSVLASLGASVHKICTDIRLLANLKEMEEPFEKQQIGSSAMPYKRNPMRSERCCSLARHLMTLVMDPLQTASVQWFERTLDDSANRRICLAEAFLTADTILNTLQNISEGLVVYPKVIERRIRQELPFMATENIIMAMVKAGGSRQDCHEKIRVLSQQAASVVKQEGGDNDLIERIQVDAYFSPIHSQLDHLLDPSSFTGRASQQVQRFLEEEVYPLLKPYESVMKVKAEL 482
[Close]
BLAST of Adenylosuccinate lyase vs. Ensembl Human
Match: ADSL (adenylosuccinate lyase [Source:HGNC Symbol;Acc:HGNC:291])

HSP 1 Score: 307.76 bits (787), Expect = 1.688e-94
Identity = 151/254 (59.45%), Postives = 196/254 (77.17%), Query Frame = 1 
Query: 1423 NQVEELDVLVSAKAGFLHHFLVTGQTYPRKLDFTIXXXXXXXXXXXHKICTDIRILANMKEIEEPFDSDQDGSSAMPYKRNPMRCERICSLARHVMTQCFNPLMTASIQWMERTLDDSANRRICIPEAFLATDGMLMTFDNVSAGLVVYQRMIEQHITAELPFMSTEAILVKMVQMGEDRQVCHEKIKRISQEAAVNVKEYGKGNDFIERLRAEPYFAKIHGDIEEVLNPYNFTGRSAEQVDRFLKTALKPLDK 2184
            ++VE+LD +V+ KAGF   F++TGQTY RK+D  +LS LA L AS+HKICTDIR+LAN+KE+EEPF+  Q GSSAMPYKRNPMR ER CSLARH+MT   +PL TAS+QW ERTLDDSANRRIC+ EAFL  D +L T  N+S GLVVY ++IE+ I  ELPFM+TE I++ MV+ G  RQ CHEKI+ +SQ+AA  VK+ G  ND IER++ + YF+ IH  ++ +L+P +FTGR+++QV RFL+  + PL K
Sbjct:  217 HKVEQLDKMVTEKAGFKRAFIITGQTYTRKVDIEVLSVLASLGASVHKICTDIRLLANLKEMEEPFEKQQIGSSAMPYKRNPMRSERCCSLARHLMTLVMDPLQTASVQWFERTLDDSANRRICLAEAFLTADTILNTLQNISEGLVVYPKVIERRIRQELPFMATENIIMAMVKAGGSRQDCHEKIRVLSQQAASVVKQEGGDNDLIERIQVDAYFSPIHSQLDHLLDPSSFTGRASQQVQRFLEEEVYPLLK 470
[Close]
BLAST of Adenylosuccinate lyase vs. Ensembl Human
Match: ADSL (adenylosuccinate lyase [Source:HGNC Symbol;Acc:HGNC:291])

HSP 1 Score: 307.375 bits (786), Expect = 2.015e-94
Identity = 151/254 (59.45%), Postives = 196/254 (77.17%), Query Frame = 1 
Query: 1423 NQVEELDVLVSAKAGFLHHFLVTGQTYPRKLDFTIXXXXXXXXXXXHKICTDIRILANMKEIEEPFDSDQDGSSAMPYKRNPMRCERICSLARHVMTQCFNPLMTASIQWMERTLDDSANRRICIPEAFLATDGMLMTFDNVSAGLVVYQRMIEQHITAELPFMSTEAILVKMVQMGEDRQVCHEKIKRISQEAAVNVKEYGKGNDFIERLRAEPYFAKIHGDIEEVLNPYNFTGRSAEQVDRFLKTALKPLDK 2184
            ++VE+LD +V+ KAGF   F++TGQTY RK+D  +LS LA L AS+HKICTDIR+LAN+KE+EEPF+  Q GSSAMPYKRNPMR ER CSLARH+MT   +PL TAS+QW ERTLDDSANRRIC+ EAFL  D +L T  N+S GLVVY ++IE+ I  ELPFM+TE I++ MV+ G  RQ CHEKI+ +SQ+AA  VK+ G  ND IER++ + YF+ IH  ++ +L+P +FTGR+++QV RFL+  + PL K
Sbjct:  217 HKVEQLDKMVTEKAGFKRAFIITGQTYTRKVDIEVLSVLASLGASVHKICTDIRLLANLKEMEEPFEKQQIGSSAMPYKRNPMRSERCCSLARHLMTLVMDPLQTASVQWFERTLDDSANRRICLAEAFLTADTILNTLQNISEGLVVYPKVIERRIRQELPFMATENIIMAMVKAGGSRQDCHEKIRVLSQQAASVVKQEGGDNDLIERIQVDAYFSPIHSQLDHLLDPSSFTGRASQQVQRFLEEEVYPLLK 470
[Close]
BLAST of Adenylosuccinate lyase vs. Ensembl Human
Match: ADSL (adenylosuccinate lyase [Source:HGNC Symbol;Acc:HGNC:291])

HSP 1 Score: 301.982 bits (772), Expect = 6.427e-94
Identity = 155/280 (55.36%), Postives = 202/280 (72.14%), Query Frame = 1 
Query: 1423 NQVEELDVLVSAKAGFLHHFLVTGQTYPRKLDFTIXXXXXXXXXXXHKICTDIRILANMKEIEEPFDSDQDGSSAMPYKRNPMRCERICSLARHVMTQCFNPLMTASIQWMERTLDDSAN--------------RRICIPEAFLATDGMLMTFDNVSAGLVVYQRMIEQHITAELPFMSTEAILVKMVQMGEDRQVCHEKIKRISQEAAVNVKEYGKGNDFIERLRAEPYFAKIHGDIEEVLNPYNFTGRSAEQVDRFLKTALKPLDK-YKHLFDEKTEL 2217
            ++VE+LD +V+ KAGF   F++TGQTY RK+D  +LS LA L AS+HKICTDIR+LAN+KE+EEPF+  Q GSSAMPYKRNPMR ER CSLARH+MT   +PL TAS+QW ERTLDDSAN              RRIC+ EAFL  D +L T  N+S GLVVY ++IE+ I  ELPFM+TE I++ MV+ G  RQ CHEKI+ +SQ+AA  VK+ G  ND IER++ + YF+ IH  ++ +L+P +FTGR+++QV RFL+  + PL K Y+ +   K EL
Sbjct:   80 HKVEQLDKMVTEKAGFKRAFIITGQTYTRKVDIEVLSVLASLGASVHKICTDIRLLANLKEMEEPFEKQQIGSSAMPYKRNPMRSERCCSLARHLMTLVMDPLQTASVQWFERTLDDSANRSVAQGHHIHQVEWRRICLAEAFLTADTILNTLQNISEGLVVYPKVIERRIRQELPFMATENIIMAMVKAGGSRQDCHEKIRVLSQQAASVVKQEGGDNDLIERIQVDAYFSPIHSQLDHLLDPSSFTGRASQQVQRFLEEEVYPLLKPYESVMKVKAEL 359
[Close]
BLAST of Adenylosuccinate lyase vs. Ensembl Celegans
Match: adsl-1 (Adenylosuccinate lyase [Source:UniProtKB/Swiss-Prot;Acc:Q21774])

HSP 1 Score: 185.267 bits (469), Expect = 2.461e-50
Identity = 102/257 (39.69%), Postives = 156/257 (60.70%), Query Frame = 1 
Query: 1423 NQVEELDVLVSAKAGFLHHFLVTGQTYPRKLDFTIXXXXXXXXXXXHKICTDIRILANMKEIEEPFDSDQDGSSAMPYKRNPMRCERICSLARHVMTQCFNPLMTASIQWMERTLDDSANRRICIPEAFLATDGMLMTFDNVSAGLVVYQRMIEQHITAELPFMSTEAILVKMVQMGEDRQVCHEKIKRISQEAAVNVKEYGKGNDFIERLRAEPYFAKIHGDIEEVL-NPYNFTGRSAEQVDRFLKTALKP-LDKY 2187
            ++VE LD LV+ KA F + FL+TGQTY R+ D  ++ +L+ L A+  K+CTDIR+L    E+ EPF+ DQ GSSAMPYK+NPM+ ER C+L+R ++      L   + Q +ERTLDDSA RR+ IP+  L  + +L T  N+  GL V    +++ +  E+ F+  E  ++ + + G DRQ  H  I++ + EA   ++   K +  I +  A+P+F  +   +  ++ NP NFTGR   Q + F+   LKP +DKY
Sbjct:  213 SKVEALDELVTKKANFSNRFLITGQTYSRQQDSQLVFSLSLLGAAAKKVCTDIRVLQAFGELLEPFEKDQIGSSAMPYKKNPMKSERCCALSRKLINAPQEALTILADQGLERTLDDSAGRRMLIPDVLLTAEALLTTLQNIFEGLSVQTDNVKKIVEDEIAFLGLEKAMMMLTEEGVDRQQAHAVIRKTALEAK-QLQATQKVD--IRQTMADPFFDSVRDRVVGLVNNPINFTGRCVSQTESFIAKELKPTIDKY 466
[Close]
BLAST of Adenylosuccinate lyase vs. Ensembl Celegans
Match: adsl-1 (Adenylosuccinate lyase [Source:UniProtKB/Swiss-Prot;Acc:Q21774])

HSP 1 Score: 185.267 bits (469), Expect = 2.461e-50
Identity = 102/257 (39.69%), Postives = 156/257 (60.70%), Query Frame = 1 
Query: 1423 NQVEELDVLVSAKAGFLHHFLVTGQTYPRKLDFTIXXXXXXXXXXXHKICTDIRILANMKEIEEPFDSDQDGSSAMPYKRNPMRCERICSLARHVMTQCFNPLMTASIQWMERTLDDSANRRICIPEAFLATDGMLMTFDNVSAGLVVYQRMIEQHITAELPFMSTEAILVKMVQMGEDRQVCHEKIKRISQEAAVNVKEYGKGNDFIERLRAEPYFAKIHGDIEEVL-NPYNFTGRSAEQVDRFLKTALKP-LDKY 2187
            ++VE LD LV+ KA F + FL+TGQTY R+ D  ++ +L+ L A+  K+CTDIR+L    E+ EPF+ DQ GSSAMPYK+NPM+ ER C+L+R ++      L   + Q +ERTLDDSA RR+ IP+  L  + +L T  N+  GL V    +++ +  E+ F+  E  ++ + + G DRQ  H  I++ + EA   ++   K +  I +  A+P+F  +   +  ++ NP NFTGR   Q + F+   LKP +DKY
Sbjct:  213 SKVEALDELVTKKANFSNRFLITGQTYSRQQDSQLVFSLSLLGAAAKKVCTDIRVLQAFGELLEPFEKDQIGSSAMPYKKNPMKSERCCALSRKLINAPQEALTILADQGLERTLDDSAGRRMLIPDVLLTAEALLTTLQNIFEGLSVQTDNVKKIVEDEIAFLGLEKAMMMLTEEGVDRQQAHAVIRKTALEAK-QLQATQKVD--IRQTMADPFFDSVRDRVVGLVNNPINFTGRCVSQTESFIAKELKPTIDKY 466
[Close]
BLAST of Adenylosuccinate lyase vs. Ensembl Celegans
Match: adsl-1 (Adenylosuccinate lyase [Source:UniProtKB/Swiss-Prot;Acc:Q21774])

HSP 1 Score: 134.42 bits (337), Expect = 6.752e-34
Identity = 67/139 (48.20%), Postives = 94/139 (67.63%), Query Frame = 1 
Query: 1423 NQVEELDVLVSAKAGFLHHFLVTGQTYPRKLDFTIXXXXXXXXXXXHKICTDIRILANMKEIEEPFDSDQDGSSAMPYKRNPMRCERICSLARHVMTQCFNPLMTASIQWMERTLDDSANRRICIPEAFLATDGMLMTF 1839
            ++VE LD LV+ KA F + FL+TGQTY R+ D  ++ +L+ L A+  K+CTDIR+L    E+ EPF+ DQ GSSAMPYK+NPM+ ER C+L+R ++      L   + Q +ERTLDDSA RR+ IP+  L  + +L T 
Sbjct:  213 SKVEALDELVTKKANFSNRFLITGQTYSRQQDSQLVFSLSLLGAAAKKVCTDIRVLQAFGELLEPFEKDQIGSSAMPYKKNPMKSERCCALSRKLINAPQEALTILADQGLERTLDDSAGRRMLIPDVLLTAEALLTTL 351
[Close]
BLAST of Adenylosuccinate lyase vs. Ensembl Fly
Match: AdSL (gene:FBgn0038467 transcript:FBtr0083373)

HSP 1 Score: 272.322 bits (695), Expect = 1.359e-81
Identity = 142/267 (53.18%), Postives = 197/267 (73.78%), Query Frame = 1 
Query: 1426 QVEELDVLVSAKAGFLHHFLVTGQTYPRKLDFTIXXXXXXXXXXXHKICTDIRILANMKEIEEPFDSDQDGSSAMPYKRNPMRCERICSLARHVMTQCFNPLMTASIQWMERTLDDSANRRICIPEAFLATDGMLMTFDNVSAGLVVYQRMIEQHITAELPFMSTEAILVKMVQMGEDRQVCHEKIKRISQEAAVNVKEYGKGNDFIERLRAEPYFAKIHGDIEEVLNPYNFTGRSAEQVDRFLKTALKP-LDKYKHLFDEKTELKV 2223
            +V++LD LV+  AGF   + VTGQTY RK+D  I++ALA L  ++HK+C+D+RILA+ KE+EEPF+S Q GSSAMPYKRNPMR ER C+LARH++T   +   T + QW+ERTLDDSANRR+ + EAFLA D  L+T  N+S GLVVY ++IE+HI+ ELPFMSTE I++ MV+ G DRQVCHEKI+ +SQEA   VK++GK ND + R+R +PYF+ I   ++ +L+   FTGR+++QV  F+K  ++P L +Y        ++K+
Sbjct:  213 KVKQLDQLVTELAGFKKAYAVTGQTYSRKVDVEIVAALASLGTTIHKMCSDLRILASRKELEEPFESTQIGSSAMPYKRNPMRSERCCALARHLITLFSSAANTHATQWLERTLDDSANRRLTLSEAFLAADAALLTLLNISQGLVVYPKVIERHISQELPFMSTENIIMAMVKAGGDRQVCHEKIRVLSQEAGAQVKQHGKDNDLVVRVRKDPYFSPILEQLDTILDAKTFTGRASDQVGEFVKEEVEPVLARYSEALKNVQDVKL 479
[Close]
BLAST of Adenylosuccinate lyase vs. Ensembl Zebrafish
Match: adsl (adenylosuccinate lyase [Source:ZFIN;Acc:ZDB-GENE-030131-6363])

HSP 1 Score: 315.079 bits (806), Expect = 2.072e-97
Identity = 155/269 (57.62%), Postives = 205/269 (76.21%), Query Frame = 1 
Query: 1420 YNQVEELDVLVSAKAGFLHHFLVTGQTYPRKLDFTIXXXXXXXXXXXHKICTDIRILANMKEIEEPFDSDQDGSSAMPYKRNPMRCERICSLARHVMTQCFNPLMTASIQWMERTLDDSANRRICIPEAFLATDGMLMTFDNVSAGLVVYQRMIEQHITAELPFMSTEAILVKMVQMGEDRQVCHEKIKRISQEAAVNVKEYGKGNDFIERLRAEPYFAKIHGDIEEVLNPYNFTGRSAEQVDRFLKTALKP-LDKYKHLFDEKTELKV 2223
            +++VEELD +V+  AGF   +LVTGQTY RK+D   L  L+ LAA++HKICTDIR+LAN+KEIEEPF+ +Q GSSAMPYKRNPMR ER CSLARH+M    NPL TA++QW+ERTLDDSANRRI +PEAFL  D +L T  N++ GLVVY ++IE+HI  ELPFM+TE I++ MV+ G +RQ CHEKI+ +SQ+AA  VK+ G  ND + R++A+PYFA I G+++ +L+P  F GR+ +QV RFL   ++P L+ YK   D K EL++
Sbjct:  214 HDKVEELDKMVTEMAGFKKSYLVTGQTYSRKVDIDSLCVLSSLAATIHKICTDIRLLANLKEIEEPFEKEQIGSSAMPYKRNPMRAERCCSLARHLMALVSNPLQTAAVQWLERTLDDSANRRISLPEAFLTADIILSTLQNITEGLVVYPKVIERHIRHELPFMATENIIMAMVKAGGNRQDCHEKIRVLSQQAAAVVKQEGGDNDLLARVQADPYFAPILGELDALLDPKTFIGRAPQQVTRFLSEEVRPVLEPYKSKMDVKIELEL 482
[Close]
BLAST of Adenylosuccinate lyase vs. Ensembl Zebrafish
Match: adsl (adenylosuccinate lyase [Source:ZFIN;Acc:ZDB-GENE-030131-6363])

HSP 1 Score: 305.449 bits (781), Expect = 7.728e-94
Identity = 154/275 (56.00%), Postives = 204/275 (74.18%), Query Frame = 1 
Query: 1420 YNQVEELDVLVSAKAGFLHHFLVTGQTYPRKLDFTIXXXXXXXXXXXHKICTDIRILANMKEIEEPFDSDQDGSSAMPYKRNPMRCERICSLARHVMTQCFNPLMTASIQWMERTLDDSANRR------ICIPEAFLATDGMLMTFDNVSAGLVVYQRMIEQHITAELPFMSTEAILVKMVQMGEDRQVCHEKIKRISQEAAVNVKEYGKGNDFIERLRAEPYFAKIHGDIEEVLNPYNFTGRSAEQVDRFLKTALKP-LDKYKHLFDEKTELKV 2223
            +++VEELD +V+  AGF   +LVTGQTY RK+D   L  L+ LAA++HKICTDIR+LAN+KEIEEPF+ +Q GSSAMPYKRNPMR ER CSLARH+M    NPL TA++QW+ERTLDDSANR       I +PEAFL  D +L T  N++ GLVVY ++IE+HI  ELPFM+TE I++ MV+ G +RQ CHEKI+ +SQ+AA  VK+ G  ND + R++A+PYFA I G+++ +L+P  F GR+ +QV RFL   ++P L+ YK   D K EL++
Sbjct:  214 HDKVEELDKMVTEMAGFKKSYLVTGQTYSRKVDIDSLCVLSSLAATIHKICTDIRLLANLKEIEEPFEKEQIGSSAMPYKRNPMRAERCCSLARHLMALVSNPLQTAAVQWLERTLDDSANRHCSHRLMISLPEAFLTADIILSTLQNITEGLVVYPKVIERHIRHELPFMATENIIMAMVKAGGNRQDCHEKIRVLSQQAAAVVKQEGGDNDLLARVQADPYFAPILGELDALLDPKTFIGRAPQQVTRFLSEEVRPVLEPYKSKMDVKIELEL 488
[Close]
BLAST of Adenylosuccinate lyase vs. Ensembl Zebrafish
Match: adsl (adenylosuccinate lyase [Source:ZFIN;Acc:ZDB-GENE-030131-6363])

HSP 1 Score: 305.064 bits (780), Expect = 1.185e-93
Identity = 154/275 (56.00%), Postives = 204/275 (74.18%), Query Frame = 1 
Query: 1420 YNQVEELDVLVSAKAGFLHHFLVTGQTYPRKLDFTIXXXXXXXXXXXHKICTDIRILANMKEIEEPFDSDQDGSSAMPYKRNPMRCERICSLARHVMTQCFNPLMTASIQWMERTLDDSANRR------ICIPEAFLATDGMLMTFDNVSAGLVVYQRMIEQHITAELPFMSTEAILVKMVQMGEDRQVCHEKIKRISQEAAVNVKEYGKGNDFIERLRAEPYFAKIHGDIEEVLNPYNFTGRSAEQVDRFLKTALKP-LDKYKHLFDEKTELKV 2223
            +++VEELD +V+  AGF   +LVTGQTY RK+D   L  L+ LAA++HKICTDIR+LAN+KEIEEPF+ +Q GSSAMPYKRNPMR ER CSLARH+M    NPL TA++QW+ERTLDDSANR       I +PEAFL  D +L T  N++ GLVVY ++IE+HI  ELPFM+TE I++ MV+ G +RQ CHEKI+ +SQ+AA  VK+ G  ND + R++A+PYFA I G+++ +L+P  F GR+ +QV RFL   ++P L+ YK   D K EL++
Sbjct:  214 HDKVEELDNMVTEMAGFKKSYLVTGQTYSRKVDIDSLCVLSSLAATIHKICTDIRLLANLKEIEEPFEKEQIGSSAMPYKRNPMRAERCCSLARHLMALVSNPLQTAAVQWLERTLDDSANRHCSHRLMISLPEAFLTADIILSTLQNITEGLVVYPKVIERHIRHELPFMATENIIMAMVKAGGNRQDCHEKIRVLSQQAAAVVKQEGGDNDLLARVQADPYFAPILGELDALLDPKTFIGRAPQQVTRFLSEEVRPVLEPYKSKMDVKIELEL 488
[Close]
BLAST of Adenylosuccinate lyase vs. Ensembl Xenopus
Match: adsl (adenylosuccinate lyase [Source:NCBI gene;Acc:448055])

HSP 1 Score: 313.153 bits (801), Expect = 7.009e-97
Identity = 155/267 (58.05%), Postives = 205/267 (76.78%), Query Frame = 1 
Query: 1420 YNQVEELDVLVSAKAGFLHHFLVTGQTYPRKLDFTIXXXXXXXXXXXHKICTDIRILANMKEIEEPFDSDQDGSSAMPYKRNPMRCERICSLARHVMTQCFNPLMTASIQWMERTLDDSANRRICIPEAFLATDGMLMTFDNVSAGLVVYQRMIEQHITAELPFMSTEAILVKMVQMGEDRQVCHEKIKRISQEAAVNVKEYGKGNDFIERLRAEPYFAKIHGDIEEVLNPYNFTGRSAEQVDRFLKTALKP-LDKYKHLFDEKTEL 2217
            +++VEELD +V++KAGF   ++VTGQTY RK+D  +LS LA L A++HKICTDIR+LAN+KE+EEPF+ +Q GSSAMPYKRNPMR ER CSLARH+MT   NPL TAS+QW ERTLDDSANRR+C+ EAFL  D +L T  N+S GLVVY ++IE+ I  ELPFM+TE I++ MV+ G +RQ CHE+I+ +SQ+AA  VK+ G  ND I R++++ YFA IH  +E++L+P +FTGR+ +QV +FLK  + P L  Y+   D K EL
Sbjct:  191 HDKVEELDRMVTSKAGFKRAYIVTGQTYSRKVDVEVLSVLASLGATVHKICTDIRLLANLKELEEPFEKEQIGSSAMPYKRNPMRSERCCSLARHLMTLIMNPLQTASVQWFERTLDDSANRRVCLAEAFLTADIILSTLQNISEGLVVYPKVIERRIRQELPFMATENIIMAMVKNGGNRQDCHERIRVLSQQAAAVVKQEGGDNDLIFRIQSDSYFAPIHAHLEQLLDPKSFTGRAPQQVLKFLKEEVIPLLSPYQSKMDVKIEL 457
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BLAST of Adenylosuccinate lyase vs. Ensembl Xenopus
Match: adsl (adenylosuccinate lyase [Source:NCBI gene;Acc:448055])

HSP 1 Score: 312.383 bits (799), Expect = 2.137e-96
Identity = 155/269 (57.62%), Postives = 206/269 (76.58%), Query Frame = 1 
Query: 1420 YNQVEELDVLVSAKAGFLHHFLVTGQTYPRKLDFTIXXXXXXXXXXXHKICTDIRILANMKEIEEPFDSDQDGSSAMPYKRNPMRCERICSLARHVMTQCFNPLMTASIQWMERTLDDSANRRICIPEAFLATDGMLMTFDNVSAGLVVYQRMIEQHITAELPFMSTEAILVKMVQMGEDRQVCHEKIKRISQEAAVNVKEYGKGNDFIERLRAEPYFAKIHGDIEEVLNPYNFTGRSAEQVDRFLKTALKP-LDKYKHLFDEKTELKV 2223
            +++VEELD +V++KAGF   ++VTGQTY RK+D  +LS LA L A++HKICTDIR+LAN+KE+EEPF+ +Q GSSAMPYKRNPMR ER CSLARH+MT   NPL TAS+QW ERTLDDSANRR+C+ EAFL  D +L T  N+S GLVVY ++IE+ I  ELPFM+TE I++ MV+ G +RQ CHE+I+ +SQ+AA  VK+ G  ND I R++++ YFA IH  +E++L+P +FTGR+ +QV +FLK  + P L  Y+   D K EL +
Sbjct:  212 HDKVEELDRMVTSKAGFKRAYIVTGQTYSRKVDVEVLSVLASLGATVHKICTDIRLLANLKELEEPFEKEQIGSSAMPYKRNPMRSERCCSLARHLMTLIMNPLQTASVQWFERTLDDSANRRVCLAEAFLTADIILSTLQNISEGLVVYPKVIERRIRQELPFMATENIIMAMVKNGGNRQDCHERIRVLSQQAAAVVKQEGGDNDLIFRIQSDSYFAPIHAHLEQLLDPKSFTGRAPQQVLKFLKEEVIPLLSPYQSKMDVKIELDL 480
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BLAST of Adenylosuccinate lyase vs. Ensembl Xenopus
Match: adsl (adenylosuccinate lyase [Source:NCBI gene;Acc:448055])

HSP 1 Score: 312.768 bits (800), Expect = 3.285e-96
Identity = 155/269 (57.62%), Postives = 206/269 (76.58%), Query Frame = 1 
Query: 1420 YNQVEELDVLVSAKAGFLHHFLVTGQTYPRKLDFTIXXXXXXXXXXXHKICTDIRILANMKEIEEPFDSDQDGSSAMPYKRNPMRCERICSLARHVMTQCFNPLMTASIQWMERTLDDSANRRICIPEAFLATDGMLMTFDNVSAGLVVYQRMIEQHITAELPFMSTEAILVKMVQMGEDRQVCHEKIKRISQEAAVNVKEYGKGNDFIERLRAEPYFAKIHGDIEEVLNPYNFTGRSAEQVDRFLKTALKP-LDKYKHLFDEKTELKV 2223
            +++VEELD +V++KAGF   ++VTGQTY RK+D  +LS LA L A++HKICTDIR+LAN+KE+EEPF+ +Q GSSAMPYKRNPMR ER CSLARH+MT   NPL TAS+QW ERTLDDSANRR+C+ EAFL  D +L T  N+S GLVVY ++IE+ I  ELPFM+TE I++ MV+ G +RQ CHE+I+ +SQ+AA  VK+ G  ND I R++++ YFA IH  +E++L+P +FTGR+ +QV +FLK  + P L  Y+   D K EL +
Sbjct:  235 HDKVEELDRMVTSKAGFKRAYIVTGQTYSRKVDVEVLSVLASLGATVHKICTDIRLLANLKELEEPFEKEQIGSSAMPYKRNPMRSERCCSLARHLMTLIMNPLQTASVQWFERTLDDSANRRVCLAEAFLTADIILSTLQNISEGLVVYPKVIERRIRQELPFMATENIIMAMVKNGGNRQDCHERIRVLSQQAAAVVKQEGGDNDLIFRIQSDSYFAPIHAHLEQLLDPKSFTGRAPQQVLKFLKEEVIPLLSPYQSKMDVKIELDL 503
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BLAST of Adenylosuccinate lyase vs. Ensembl Xenopus
Match: adsl (adenylosuccinate lyase [Source:NCBI gene;Acc:448055])

HSP 1 Score: 301.597 bits (771), Expect = 4.023e-92
Identity = 146/247 (59.11%), Postives = 194/247 (78.54%), Query Frame = 1 
Query: 1420 YNQVEELDVLVSAKAGFLHHFLVTGQTYPRKLDFTIXXXXXXXXXXXHKICTDIRILANMKEIEEPFDSDQDGSSAMPYKRNPMRCERICSLARHVMTQCFNPLMTASIQWMERTLDDSANRRICIPEAFLATDGMLMTFDNVSAGLVVYQRMIEQHITAELPFMSTEAILVKMVQMGEDRQVCHEKIKRISQEAAVNVKEYGKGNDFIERLRAEPYFAKIHGDIEEVLNPYNFTGRSAEQVDRFLK 2160
            +++VEELD +V++KAGF   ++VTGQTY RK+D  +LS LA L A++HKICTDIR+LAN+KE+EEPF+ +Q GSSAMPYKRNPMR ER CSLARH+MT   NPL TAS+QW ERTLDDSANRR+C+ EAFL  D +L T  N+S GLVVY ++IE+ I  ELPFM+TE I++ MV+ G +RQ CHE+I+ +SQ+AA  VK+ G  ND I R++++ YFA IH  +E++L+P +FTGR+ +QV +  K
Sbjct:  235 HDKVEELDRMVTSKAGFKRAYIVTGQTYSRKVDVEVLSVLASLGATVHKICTDIRLLANLKELEEPFEKEQIGSSAMPYKRNPMRSERCCSLARHLMTLIMNPLQTASVQWFERTLDDSANRRVCLAEAFLTADIILSTLQNISEGLVVYPKVIERRIRQELPFMATENIIMAMVKNGGNRQDCHERIRVLSQQAAAVVKQEGGDNDLIFRIQSDSYFAPIHAHLEQLLDPKSFTGRAPQQVRQISK 481
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BLAST of Adenylosuccinate lyase vs. Ensembl Xenopus
Match: adsl (adenylosuccinate lyase [Source:NCBI gene;Acc:448055])

HSP 1 Score: 300.827 bits (769), Expect = 6.030e-92
Identity = 149/253 (58.89%), Postives = 197/253 (77.87%), Query Frame = 1 
Query: 1420 YNQVEELDVLVSAKAGFLHHFLVTGQTYPRKLDFTIXXXXXXXXXXXHKICTDIRILANMKEIEEPFDSDQDGSSAMPYKRNPMRCERICSLARHVMTQCFNPLMTASIQWMERTLDDSANRRICIPEAFLATDGMLMTFDNVSAGLVVYQRMIEQHITAELPFMSTEAILVKMVQMGEDRQVCHEKIKRISQEAAVNVKEYGKGNDFIERLRAEPYFAKIHGDIEEVLNPYNFTGRSAEQVDRFLKTALKPL 2178
            +++VEELD +V++KAGF   ++VTGQTY RK+D  +LS LA L A++HKICTDIR+LAN+KE+EEPF+ +Q GSSAMPYKRNPMR ER CSLARH+MT   NPL TAS+QW ERTLDDSANRR+C+ EAFL  D +L T  N+S GLVVY ++IE+ I  ELPFM+TE I++ MV+ G +RQ CHE+I+ +SQ+AA  VK+ G  ND I R++++ YFA IH  +E++L+P +FTGR+ +QV R  K  L P+
Sbjct:  191 HDKVEELDRMVTSKAGFKRAYIVTGQTYSRKVDVEVLSVLASLGATVHKICTDIRLLANLKELEEPFEKEQIGSSAMPYKRNPMRSERCCSLARHLMTLIMNPLQTASVQWFERTLDDSANRRVCLAEAFLTADIILSTLQNISEGLVVYPKVIERRIRQELPFMATENIIMAMVKNGGNRQDCHERIRVLSQQAAAVVKQEGGDNDLIFRIQSDSYFAPIHAHLEQLLDPKSFTGRAPQQV-RQTKKILIPV 442
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BLAST of Adenylosuccinate lyase vs. Ensembl Mouse
Match: Adsl (adenylosuccinate lyase [Source:MGI Symbol;Acc:MGI:103202])

HSP 1 Score: 313.153 bits (801), Expect = 6.861e-97
Identity = 157/267 (58.80%), Postives = 201/267 (75.28%), Query Frame = 1 
Query: 1420 YNQVEELDVLVSAKAGFLHHFLVTGQTYPRKLDFTIXXXXXXXXXXXHKICTDIRILANMKEIEEPFDSDQDGSSAMPYKRNPMRCERICSLARHVMTQCFNPLMTASIQWMERTLDDSANRRICIPEAFLATDGMLMTFDNVSAGLVVYQRMIEQHITAELPFMSTEAILVKMVQMGEDRQVCHEKIKRISQEAAVNVKEYGKGNDFIERLRAEPYFAKIHGDIEEVLNPYNFTGRSAEQVDRFLKTALKPLDK-YKHLFDEKTEL 2217
            + +VE+LD +V+ KAGF   F++TGQTY RK+D  +LS LA L AS+HKICTDIR+LAN+KE+EEPF+  Q GSSAMPYKRNPMR ER CSLARH+M    +PL TAS+QW ERTLDDSANRRIC+ EAFL  D +L T  N+S GLVVY ++IE+ I  ELPFM+TE I++ MV+ G  RQ CHEKI+ +SQ+AA  VK+ G  ND IER+RA+ YF+ IH  +E +L+P +FTGR+ +QV RFL+  ++PL K Y +    K EL
Sbjct:  201 HQKVEQLDKMVTEKAGFKRAFIITGQTYTRKVDIEVLSVLASLGASVHKICTDIRLLANLKEMEEPFEKQQIGSSAMPYKRNPMRSERCCSLARHLMALTMDPLQTASVQWFERTLDDSANRRICLAEAFLTADTILNTLQNISEGLVVYPKVIERRIRQELPFMATENIIMAMVKAGGSRQDCHEKIRVLSQQAAAVVKQEGGDNDLIERIRADAYFSPIHSQLEHLLDPSSFTGRAPQQVHRFLEEEVRPLLKPYGNEMAVKAEL 467
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BLAST of Adenylosuccinate lyase vs. Ensembl Mouse
Match: Adsl (adenylosuccinate lyase [Source:MGI Symbol;Acc:MGI:103202])

HSP 1 Score: 313.153 bits (801), Expect = 1.035e-96
Identity = 157/267 (58.80%), Postives = 201/267 (75.28%), Query Frame = 1 
Query: 1420 YNQVEELDVLVSAKAGFLHHFLVTGQTYPRKLDFTIXXXXXXXXXXXHKICTDIRILANMKEIEEPFDSDQDGSSAMPYKRNPMRCERICSLARHVMTQCFNPLMTASIQWMERTLDDSANRRICIPEAFLATDGMLMTFDNVSAGLVVYQRMIEQHITAELPFMSTEAILVKMVQMGEDRQVCHEKIKRISQEAAVNVKEYGKGNDFIERLRAEPYFAKIHGDIEEVLNPYNFTGRSAEQVDRFLKTALKPLDK-YKHLFDEKTEL 2217
            + +VE+LD +V+ KAGF   F++TGQTY RK+D  +LS LA L AS+HKICTDIR+LAN+KE+EEPF+  Q GSSAMPYKRNPMR ER CSLARH+M    +PL TAS+QW ERTLDDSANRRIC+ EAFL  D +L T  N+S GLVVY ++IE+ I  ELPFM+TE I++ MV+ G  RQ CHEKI+ +SQ+AA  VK+ G  ND IER+RA+ YF+ IH  +E +L+P +FTGR+ +QV RFL+  ++PL K Y +    K EL
Sbjct:  216 HQKVEQLDKMVTEKAGFKRAFIITGQTYTRKVDIEVLSVLASLGASVHKICTDIRLLANLKEMEEPFEKQQIGSSAMPYKRNPMRSERCCSLARHLMALTMDPLQTASVQWFERTLDDSANRRICLAEAFLTADTILNTLQNISEGLVVYPKVIERRIRQELPFMATENIIMAMVKAGGSRQDCHEKIRVLSQQAAAVVKQEGGDNDLIERIRADAYFSPIHSQLEHLLDPSSFTGRAPQQVHRFLEEEVRPLLKPYGNEMAVKAEL 482
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BLAST of Adenylosuccinate lyase vs. Ensembl Mouse
Match: Adsl (adenylosuccinate lyase [Source:MGI Symbol;Acc:MGI:103202])

HSP 1 Score: 233.802 bits (595), Expect = 5.648e-68
Identity = 116/183 (63.39%), Postives = 143/183 (78.14%), Query Frame = 1 
Query: 1420 YNQVEELDVLVSAKAGFLHHFLVTGQTYPRKLDFTIXXXXXXXXXXXHKICTDIRILANMKEIEEPFDSDQDGSSAMPYKRNPMRCERICSLARHVMTQCFNPLMTASIQWMERTLDDSANRRICIPEAFLATDGMLMTFDNVSAGLVVYQRMIEQHITAELPFMSTEAILVKMVQMGEDRQV 1968
            + +VE+LD +V+ KAGF   F++TGQTY RK+D  +LS LA L AS+HKICTDIR+LAN+KE+EEPF+  Q GSSAMPYKRNPMR ER CSLARH+M    +PL TAS+QW ERTLDDSANRRIC+ EAFL  D +L T  N+S GLVVY ++IE+ I  ELPFM+TE I++ MV+ G  RQV
Sbjct:  216 HQKVEQLDKMVTEKAGFKRAFIITGQTYTRKVDIEVLSVLASLGASVHKICTDIRLLANLKEMEEPFEKQQIGSSAMPYKRNPMRSERCCSLARHLMALTMDPLQTASVQWFERTLDDSANRRICLAEAFLTADTILNTLQNISEGLVVYPKVIERRIRQELPFMATENIIMAMVKAGGSRQV 398
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BLAST of Adenylosuccinate lyase vs. Ensembl Mouse
Match: Adsl (adenylosuccinate lyase [Source:MGI Symbol;Acc:MGI:103202])

HSP 1 Score: 130.954 bits (328), Expect = 5.309e-35
Identity = 65/97 (67.01%), Postives = 80/97 (82.47%), Query Frame = 1 
Query: 1420 YNQVEELDVLVSAKAGFLHHFLVTGQTYPRKLDFTIXXXXXXXXXXXHKICTDIRILANMKEIEEPFDSDQDGSSAMPYKRNPMRCERICSLARHVM 1710
            + +VE+LD +V+ KAGF   F++TGQTY RK+D  +LS LA L AS+HKICTDIR+LAN+KE+EEPF+  Q GSSAMPYKRNPMR ER CSLARH+M
Sbjct:   36 HQKVEQLDKMVTEKAGFKRAFIITGQTYTRKVDIEVLSVLASLGASVHKICTDIRLLANLKEMEEPFEKQQIGSSAMPYKRNPMRSERCCSLARHLM 132
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BLAST of Adenylosuccinate lyase vs. Ensembl Mouse
Match: Adsl (adenylosuccinate lyase [Source:MGI Symbol;Acc:MGI:103202])

HSP 1 Score: 58.5362 bits (140), Expect = 8.396e-11
Identity = 25/35 (71.43%), Postives = 28/35 (80.00%), Query Frame = 1 
Query: 1681 RICSLARHVMTQCFNPLMTASIQWMERTLDDSANR 1785
            R CSLARH+M    +PL TAS+QW ERTLDDSANR
Sbjct:    2 RCCSLARHLMALTMDPLQTASVQWFERTLDDSANR 36
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BLAST of Adenylosuccinate lyase vs. UniProt/SwissProt
Match: sp|P21265|PUR8_CHICK (Adenylosuccinate lyase OS=Gallus gallus OX=9031 GN=ADSL PE=2 SV=2)

HSP 1 Score: 323.553 bits (828), Expect = 9.786e-100
Identity = 160/269 (59.48%), Postives = 208/269 (77.32%), Query Frame = 1 
Query: 1420 YNQVEELDVLVSAKAGFLHHFLVTGQTYPRKLDFTIXXXXXXXXXXXHKICTDIRILANMKEIEEPFDSDQDGSSAMPYKRNPMRCERICSLARHVMTQCFNPLMTASIQWMERTLDDSANRRICIPEAFLATDGMLMTFDNVSAGLVVYQRMIEQHITAELPFMSTEAILVKMVQMGEDRQVCHEKIKRISQEAAVNVKEYGKGNDFIERLRAEPYFAKIHGDIEEVLNPYNFTGRSAEQVDRFLKTALKP-LDKYKHLFDEKTELKV 2223
            +++VEELD LV+AKAGF   ++VTGQTY RK+D  +LS LA L AS+HKICTDIR+LAN+KEIEEPF+ DQ GSSAMPYKRNPMR ER CSLARH+MT   +PL TAS+QW ERTLDDSANRR+C+ EAFL  D +L T  N+S GLVVY ++I++ I  ELPFM+TE I++ MV+ G +RQ CHEKI+ +SQ+AA  VK+ G  NDFI R+RA+PYF+ IH  ++ +L+P +FTGR+ +QV +FLK  ++P L  Y+ +   K EL +
Sbjct:  217 HSKVEELDRLVTAKAGFKRSYMVTGQTYSRKVDIEVLSVLASLGASVHKICTDIRLLANLKEIEEPFEKDQIGSSAMPYKRNPMRSERCCSLARHLMTLVLDPLQTASVQWFERTLDDSANRRVCLAEAFLTADIILSTLQNISEGLVVYPKVIDRRIRQELPFMATENIIMAMVKAGGNRQDCHEKIRVLSQQAAAVVKQEGGDNDFIARVRADPYFSPIHEHLDSLLDPSSFTGRAPQQVAKFLKEEVRPALIPYQSMMGGKIELTL 485
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BLAST of Adenylosuccinate lyase vs. UniProt/SwissProt
Match: sp|P54822|PUR8_MOUSE (Adenylosuccinate lyase OS=Mus musculus OX=10090 GN=Adsl PE=1 SV=2)

HSP 1 Score: 313.153 bits (801), Expect = 7.243e-96
Identity = 157/267 (58.80%), Postives = 201/267 (75.28%), Query Frame = 1 
Query: 1420 YNQVEELDVLVSAKAGFLHHFLVTGQTYPRKLDFTIXXXXXXXXXXXHKICTDIRILANMKEIEEPFDSDQDGSSAMPYKRNPMRCERICSLARHVMTQCFNPLMTASIQWMERTLDDSANRRICIPEAFLATDGMLMTFDNVSAGLVVYQRMIEQHITAELPFMSTEAILVKMVQMGEDRQVCHEKIKRISQEAAVNVKEYGKGNDFIERLRAEPYFAKIHGDIEEVLNPYNFTGRSAEQVDRFLKTALKPLDK-YKHLFDEKTEL 2217
            + +VE+LD +V+ KAGF   F++TGQTY RK+D  +LS LA L AS+HKICTDIR+LAN+KE+EEPF+  Q GSSAMPYKRNPMR ER CSLARH+M    +PL TAS+QW ERTLDDSANRRIC+ EAFL  D +L T  N+S GLVVY ++IE+ I  ELPFM+TE I++ MV+ G  RQ CHEKI+ +SQ+AA  VK+ G  ND IER+RA+ YF+ IH  +E +L+P +FTGR+ +QV RFL+  ++PL K Y +    K EL
Sbjct:  216 HQKVEQLDKMVTEKAGFKRAFIITGQTYTRKVDIEVLSVLASLGASVHKICTDIRLLANLKEMEEPFEKQQIGSSAMPYKRNPMRSERCCSLARHLMALTMDPLQTASVQWFERTLDDSANRRICLAEAFLTADTILNTLQNISEGLVVYPKVIERRIRQELPFMATENIIMAMVKAGGSRQDCHEKIRVLSQQAAAVVKQEGGDNDLIERIRADAYFSPIHSQLEHLLDPSSFTGRAPQQVHRFLEEEVRPLLKPYGNEMAVKAEL 482
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BLAST of Adenylosuccinate lyase vs. UniProt/SwissProt
Match: sp|Q8HXY5|PUR8_MACFA (Adenylosuccinate lyase OS=Macaca fascicularis OX=9541 GN=ADSL PE=2 SV=1)

HSP 1 Score: 311.997 bits (798), Expect = 1.779e-95
Identity = 156/266 (58.65%), Postives = 203/266 (76.32%), Query Frame = 1 
Query: 1423 NQVEELDVLVSAKAGFLHHFLVTGQTYPRKLDFTIXXXXXXXXXXXHKICTDIRILANMKEIEEPFDSDQDGSSAMPYKRNPMRCERICSLARHVMTQCFNPLMTASIQWMERTLDDSANRRICIPEAFLATDGMLMTFDNVSAGLVVYQRMIEQHITAELPFMSTEAILVKMVQMGEDRQVCHEKIKRISQEAAVNVKEYGKGNDFIERLRAEPYFAKIHGDIEEVLNPYNFTGRSAEQVDRFLKTALKPLDK-YKHLFDEKTEL 2217
            ++VE+LD +V+ KAGF   F++TGQTY RK+D  +LS LA L AS+HKICTDIR+LAN+KE+EEPF+  Q GSSAMPYKRNPMR ER CSLARH+MT   +PL TAS+QW ERTLDDSANRRIC+ EAFL  D +L T  N+S GLVVY ++IE+ I  ELPFM+TE I++ MV+ G  RQ CHEKI+ +SQ+AA  VK+ G  ND IER++A+ YF+ IH  ++ +L+P +FTGR+++QV RFL+  + PL K Y+ +   K EL
Sbjct:  217 HKVEQLDKMVTDKAGFKRAFIITGQTYTRKVDIEVLSVLASLGASVHKICTDIRLLANLKEMEEPFEKQQIGSSAMPYKRNPMRSERCCSLARHLMTLVMDPLQTASVQWFERTLDDSANRRICLAEAFLTADTILNTLQNISEGLVVYPKVIERRIRQELPFMATENIIMAMVKAGGSRQDCHEKIRVLSQQAASVVKQEGGDNDLIERIQADAYFSPIHSQLDRLLDPSSFTGRASQQVQRFLEEEVYPLLKPYESVMKVKAEL 482
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BLAST of Adenylosuccinate lyase vs. UniProt/SwissProt
Match: sp|P30566|PUR8_HUMAN (Adenylosuccinate lyase OS=Homo sapiens OX=9606 GN=ADSL PE=1 SV=2)

HSP 1 Score: 310.071 bits (793), Expect = 9.460e-95
Identity = 155/266 (58.27%), Postives = 202/266 (75.94%), Query Frame = 1 
Query: 1423 NQVEELDVLVSAKAGFLHHFLVTGQTYPRKLDFTIXXXXXXXXXXXHKICTDIRILANMKEIEEPFDSDQDGSSAMPYKRNPMRCERICSLARHVMTQCFNPLMTASIQWMERTLDDSANRRICIPEAFLATDGMLMTFDNVSAGLVVYQRMIEQHITAELPFMSTEAILVKMVQMGEDRQVCHEKIKRISQEAAVNVKEYGKGNDFIERLRAEPYFAKIHGDIEEVLNPYNFTGRSAEQVDRFLKTALKPLDK-YKHLFDEKTEL 2217
            ++VE+LD +V+ KAGF   F++TGQTY RK+D  +LS LA L AS+HKICTDIR+LAN+KE+EEPF+  Q GSSAMPYKRNPMR ER CSLARH+MT   +PL TAS+QW ERTLDDSANRRIC+ EAFL  D +L T  N+S GLVVY ++IE+ I  ELPFM+TE I++ MV+ G  RQ CHEKI+ +SQ+AA  VK+ G  ND IER++ + YF+ IH  ++ +L+P +FTGR+++QV RFL+  + PL K Y+ +   K EL
Sbjct:  217 HKVEQLDKMVTEKAGFKRAFIITGQTYTRKVDIEVLSVLASLGASVHKICTDIRLLANLKEMEEPFEKQQIGSSAMPYKRNPMRSERCCSLARHLMTLVMDPLQTASVQWFERTLDDSANRRICLAEAFLTADTILNTLQNISEGLVVYPKVIERRIRQELPFMATENIIMAMVKAGGSRQDCHEKIRVLSQQAASVVKQEGGDNDLIERIQVDAYFSPIHSQLDHLLDPSSFTGRASQQVQRFLEEEVYPLLKPYESVMKVKAEL 482
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BLAST of Adenylosuccinate lyase vs. UniProt/SwissProt
Match: sp|A3KN12|PUR8_BOVIN (Adenylosuccinate lyase OS=Bos taurus OX=9913 GN=ADSL PE=2 SV=1)

HSP 1 Score: 309.301 bits (791), Expect = 2.707e-94
Identity = 153/268 (57.09%), Postives = 203/268 (75.75%), Query Frame = 1 
Query: 1423 NQVEELDVLVSAKAGFLHHFLVTGQTYPRKLDFTIXXXXXXXXXXXHKICTDIRILANMKEIEEPFDSDQDGSSAMPYKRNPMRCERICSLARHVMTQCFNPLMTASIQWMERTLDDSANRRICIPEAFLATDGMLMTFDNVSAGLVVYQRMIEQHITAELPFMSTEAILVKMVQMGEDRQVCHEKIKRISQEAAVNVKEYGKGNDFIERLRAEPYFAKIHGDIEEVLNPYNFTGRSAEQVDRFLKTALKPLDK-YKHLFDEKTELKV 2223
             +VE+LD +V+ KAGF   F++TGQTY RK+D  +LS LA L AS+HKICTDIR+LAN+KE+EEPF+  Q GSSAMPYKRNPMR ER CSLARH+M    +PL TAS+QW ERTLDDSANRRIC+ EAFL  D +L T  N+S GLVVY ++IE+ +  ELPFM+TE I++ MV+ G +RQ C EKI+ +SQ+AA  VK+ G  ND IER++A+ YF+ IH  ++ +L+P +FTGR+++QV RFL+  + PL K Y+ +   K EL++
Sbjct:  223 QKVEQLDKMVTEKAGFKRAFIITGQTYTRKVDIEVLSVLASLGASVHKICTDIRLLANLKEMEEPFEKQQIGSSAMPYKRNPMRSERCCSLARHLMALVMDPLQTASVQWFERTLDDSANRRICLAEAFLTADTVLNTLQNISEGLVVYPKVIERRVQQELPFMATENIIMAMVKAGGNRQDCREKIRVLSQQAAAVVKQEGGDNDLIERIQADAYFSPIHSQLDHLLDPSSFTGRASQQVQRFLEEEVCPLLKPYESVMKVKAELRL 490
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BLAST of Adenylosuccinate lyase vs. TrEMBL
Match: A0A091TLB3 (Adenylosuccinate lyase (Fragment) OS=Pelecanus crispus OX=36300 GN=N334_11387 PE=4 SV=1)

HSP 1 Score: 326.25 bits (835), Expect = 1.710e-100
Identity = 162/269 (60.22%), Postives = 207/269 (76.95%), Query Frame = 1 
Query: 1420 YNQVEELDVLVSAKAGFLHHFLVTGQTYPRKLDFTIXXXXXXXXXXXHKICTDIRILANMKEIEEPFDSDQDGSSAMPYKRNPMRCERICSLARHVMTQCFNPLMTASIQWMERTLDDSANRRICIPEAFLATDGMLMTFDNVSAGLVVYQRMIEQHITAELPFMSTEAILVKMVQMGEDRQVCHEKIKRISQEAAVNVKEYGKGNDFIERLRAEPYFAKIHGDIEEVLNPYNFTGRSAEQVDRFLKTALKP-LDKYKHLFDEKTELKV 2223
            +++VEELD LV+AKAGF   ++VTGQTY RK+D  +LS LA L AS+HKICTDIR+LAN+KEIEEPF+ DQ GSSAMPYKRNPMR ER CSLARH+MT   +PL TAS+QW ERTLDDSANRR+C+ EAFL  D +L T  N+S GLVVY ++IE+ I  ELPFM+TE I++ MV+ G +RQ CHEKI+ +SQ+AA  VK+ G  NDFI R+RA+PYF+ IH  +E +L+P +FTGR+ +QV +FLK  ++P L  Y+     K EL +
Sbjct:   57 HSKVEELDRLVTAKAGFKRAYMVTGQTYSRKVDIEVLSVLASLGASIHKICTDIRLLANLKEIEEPFEKDQIGSSAMPYKRNPMRSERCCSLARHLMTLVLDPLQTASVQWFERTLDDSANRRVCLAEAFLTADIILSTLQNISEGLVVYPKVIERRIRQELPFMATENIIMAMVKAGGNRQDCHEKIRVLSQQAAAVVKQEGGDNDFIARVRADPYFSPIHKQLESLLDPSSFTGRAPQQVAKFLKEEVRPALIPYQSKMGGKIELAL 325
[Close]
BLAST of Adenylosuccinate lyase vs. TrEMBL
Match: A0A094ME25 (Adenylosuccinate lyase (Fragment) OS=Antrostomus carolinensis OX=279965 GN=N321_10974 PE=4 SV=1)

HSP 1 Score: 323.939 bits (829), Expect = 1.352e-99
Identity = 161/269 (59.85%), Postives = 207/269 (76.95%), Query Frame = 1 
Query: 1420 YNQVEELDVLVSAKAGFLHHFLVTGQTYPRKLDFTIXXXXXXXXXXXHKICTDIRILANMKEIEEPFDSDQDGSSAMPYKRNPMRCERICSLARHVMTQCFNPLMTASIQWMERTLDDSANRRICIPEAFLATDGMLMTFDNVSAGLVVYQRMIEQHITAELPFMSTEAILVKMVQMGEDRQVCHEKIKRISQEAAVNVKEYGKGNDFIERLRAEPYFAKIHGDIEEVLNPYNFTGRSAEQVDRFLKTALKP-LDKYKHLFDEKTELKV 2223
            +++VEELD LV+AKAGF   ++VTGQTY RK+D  +LS LA L AS+HKICTDIR+LAN+KEIEEPF+ DQ GSSAMPYKRNPMR ER CSLARH+MT   +PL TAS+QW ERTLDDSANRR+C+ EAFL  D +L T  N+S GLVVY ++IE+ I  ELPFM+TE I++ MV+ G +RQ CHEKI+ +SQ+AA  VK+ G  NDFI R++A+PYF+ IH  +E +L+P +FTGR+ +QV +FLK  ++P L  Y+     K EL +
Sbjct:   57 HSKVEELDRLVTAKAGFKRAYMVTGQTYSRKVDIEVLSVLASLGASIHKICTDIRLLANLKEIEEPFEKDQIGSSAMPYKRNPMRSERCCSLARHLMTLVLDPLQTASVQWFERTLDDSANRRVCLAEAFLTADIILSTLQNISEGLVVYPKVIERRIRQELPFMATENIIMAMVKAGGNRQDCHEKIRVLSQKAAAVVKQEGGDNDFIARVQADPYFSPIHKQLESLLDPSSFTGRAPQQVAKFLKEEVRPALIPYQSKMGGKIELAL 325
[Close]
BLAST of Adenylosuccinate lyase vs. TrEMBL
Match: G3W610 (Adenylosuccinate lyase OS=Sarcophilus harrisii OX=9305 GN=ADSL PE=3 SV=1)

HSP 1 Score: 327.02 bits (837), Expect = 5.437e-99
Identity = 162/269 (60.22%), Postives = 207/269 (76.95%), Query Frame = 1 
Query: 1420 YNQVEELDVLVSAKAGFLHHFLVTGQTYPRKLDFTIXXXXXXXXXXXHKICTDIRILANMKEIEEPFDSDQDGSSAMPYKRNPMRCERICSLARHVMTQCFNPLMTASIQWMERTLDDSANRRICIPEAFLATDGMLMTFDNVSAGLVVYQRMIEQHITAELPFMSTEAILVKMVQMGEDRQVCHEKIKRISQEAAVNVKEYGKGNDFIERLRAEPYFAKIHGDIEEVLNPYNFTGRSAEQVDRFLKTALKPLDK-YKHLFDEKTELKV 2223
            + +VEELD +V+ KAGF   F++TGQTY RK+D  +LS LA L AS+HKICTDIR+LAN+KE+EEPF+  Q GSSAMPYKRNPMRCER CSLARH+MT   +PL TAS+QW+ERTLDDSANRR+C+ EAFL  D +L T  NVS GLVVY ++IE+ I  ELPFM+TE I++ MV+ G  RQ CHE+I+ +SQEAA  VK+ G  ND I R+RA+PYF+ IH  +E +L+P +FTGR+A+QV+RFLK  ++ L K Y+   D K EL +
Sbjct:  183 HQKVEELDRMVTEKAGFRRAFIITGQTYTRKVDIEVLSVLASLGASVHKICTDIRLLANLKELEEPFEKQQIGSSAMPYKRNPMRCERCCSLARHLMTLVADPLQTASVQWLERTLDDSANRRLCLAEAFLTADTILNTLQNVSEGLVVYPKVIERRIRQELPFMATENIIMAMVKAGGSRQDCHERIRVLSQEAAAVVKQEGGDNDLIARIRADPYFSPIHAQLERLLDPSSFTGRAAQQVERFLKEEVQHLLKSYQSQMDVKVELSL 451
[Close]
BLAST of Adenylosuccinate lyase vs. TrEMBL
Match: A0A0A0A2J8 (Adenylosuccinate lyase (Fragment) OS=Charadrius vociferus OX=50402 GN=N301_05942 PE=3 SV=1)

HSP 1 Score: 325.479 bits (833), Expect = 9.602e-99
Identity = 162/269 (60.22%), Postives = 207/269 (76.95%), Query Frame = 1 
Query: 1420 YNQVEELDVLVSAKAGFLHHFLVTGQTYPRKLDFTIXXXXXXXXXXXHKICTDIRILANMKEIEEPFDSDQDGSSAMPYKRNPMRCERICSLARHVMTQCFNPLMTASIQWMERTLDDSANRRICIPEAFLATDGMLMTFDNVSAGLVVYQRMIEQHITAELPFMSTEAILVKMVQMGEDRQVCHEKIKRISQEAAVNVKEYGKGNDFIERLRAEPYFAKIHGDIEEVLNPYNFTGRSAEQVDRFLKTALKP-LDKYKHLFDEKTELKV 2223
            +++VEELD LV+AKAGF   ++VTGQTY RK+D  +LS LA L AS+HKICTDIR+LAN+KEIEEPF+ DQ GSSAMPYKRNPMR ER CSLARH+MT   +PL TAS+QW ERTLDDSANRR+C+ EAFL  D +L T  N+S GLVVY ++IE+ I  ELPFM+TE I++ MV+ G +RQ CHEKI+ +SQ+AA  VK+ G  NDFI R+RA+PYF+ IH  +E +L+P +FTGR+ +QV +FLK  ++P L  Y+     K EL +
Sbjct:  166 HSKVEELDRLVTAKAGFKRSYMVTGQTYSRKVDIEVLSVLASLGASIHKICTDIRLLANLKEIEEPFEKDQIGSSAMPYKRNPMRSERCCSLARHLMTLVLDPLQTASVQWFERTLDDSANRRVCLAEAFLTADIILSTLQNISEGLVVYPKVIERRIRQELPFMATENIIMAMVKAGGNRQDCHEKIRVLSQQAAAVVKQEGGDNDFIARVRADPYFSPIHKQLESLLDPSSFTGRAPQQVAKFLKEEVRPALIPYQSKMGGKIELAL 434
[Close]
BLAST of Adenylosuccinate lyase vs. TrEMBL
Match: A0A093H8I5 (Adenylosuccinate lyase (Fragment) OS=Struthio camelus australis OX=441894 GN=N308_03303 PE=3 SV=1)

HSP 1 Score: 325.479 bits (833), Expect = 1.249e-98
Identity = 162/269 (60.22%), Postives = 207/269 (76.95%), Query Frame = 1 
Query: 1420 YNQVEELDVLVSAKAGFLHHFLVTGQTYPRKLDFTIXXXXXXXXXXXHKICTDIRILANMKEIEEPFDSDQDGSSAMPYKRNPMRCERICSLARHVMTQCFNPLMTASIQWMERTLDDSANRRICIPEAFLATDGMLMTFDNVSAGLVVYQRMIEQHITAELPFMSTEAILVKMVQMGEDRQVCHEKIKRISQEAAVNVKEYGKGNDFIERLRAEPYFAKIHGDIEEVLNPYNFTGRSAEQVDRFLKTALKP-LDKYKHLFDEKTELKV 2223
            +++VEELD LV+AKAGF   ++VTGQTY RK+D  +LS LA L AS+HKICTDIR+LAN+KEIEEPF+ DQ GSSAMPYKRNPMR ER CSLARH+MT   +PL TAS+QW ERTLDDSANRR+C+ EAFL  D +L T  N+S GLVVY ++IE+ I  ELPFM+TE I++ MV+ G +RQ CHEKI+ +SQ+AA  VK+ G  ND I R+RA+PYF+ IHG +E +L+P +FTGR+ +QV +FLK  ++P L  Y+     K EL +
Sbjct:  166 HSKVEELDRLVTAKAGFKRAYIVTGQTYSRKVDIEVLSVLASLGASIHKICTDIRLLANLKEIEEPFEKDQIGSSAMPYKRNPMRSERCCSLARHLMTLILDPLQTASVQWFERTLDDSANRRVCLAEAFLTADIILSTLQNISEGLVVYPKVIERRIRQELPFMATENIIMAMVKAGGNRQDCHEKIRVLSQQAAAVVKQEGGDNDLIARVRADPYFSPIHGRLESLLDPSSFTGRAPQQVAKFLKEEVQPALMPYQSKMGGKIELAL 434
[Close]
BLAST of Adenylosuccinate lyase vs. Ensembl Cavefish
Match: adsl (adenylosuccinate lyase [Source:NCBI gene;Acc:103028733])

HSP 1 Score: 306.99 bits (785), Expect = 1.608e-94
Identity = 153/269 (56.88%), Postives = 202/269 (75.09%), Query Frame = 1 
Query: 1420 YNQVEELDVLVSAKAGFLHHFLVTGQTYPRKLDFTIXXXXXXXXXXXHKICTDIRILANMKEIEEPFDSDQDGSSAMPYKRNPMRCERICSLARHVMTQCFNPLMTASIQWMERTLDDSANRRICIPEAFLATDGMLMTFDNVSAGLVVYQRMIEQHITAELPFMSTEAILVKMVQMGEDRQVCHEKIKRISQEAAVNVKEYGKGNDFIERLRAEPYFAKIHGDIEEVLNPYNFTGRSAEQVDRFLKTALKP-LDKYKHLFDEKTELKV 2223
            +++VEELD  V+  AGF   +LVTGQTY RK+D   LS LA L A++HKICTDIR+LAN+KEIEEPF+ +Q GSSAMPYKRNPMR ER CSLARH++    +PL TA++QW+ERTLDDSANRRI +PE+FL  D +L T  N++ GLVVY ++IE+HI  ELPFM+TE +++ MVQ G +RQ CHEKI+ +SQ+AA  VK+ G  ND + R+RA+PYF  I   ++ +L+P  F GR+ +QV RFL   +KP L+ YK+  D K EL++
Sbjct:  214 HDKVEELDRKVTEMAGFKKSYLVTGQTYSRKVDIDSLSVLASLGATVHKICTDIRLLANLKEIEEPFEKEQIGSSAMPYKRNPMRAERCCSLARHLVALVSDPLQTAAVQWLERTLDDSANRRISLPESFLTADIILSTLQNITEGLVVYPKVIERHIRHELPFMATENLIMAMVQAGGNRQDCHEKIRVLSQQAAAVVKQEGGDNDLLARVRADPYFTPILNQLDALLDPKTFIGRAPQQVTRFLTEEVKPVLEPYKNKMDVKIELEL 482
[Close]
BLAST of Adenylosuccinate lyase vs. Ensembl Cavefish
Match: adsl (adenylosuccinate lyase [Source:NCBI gene;Acc:103028733])

HSP 1 Score: 230.72 bits (587), Expect = 5.186e-67
Identity = 114/183 (62.30%), Postives = 145/183 (79.23%), Query Frame = 1 
Query: 1420 YNQVEELDVLVSAKAGFLHHFLVTGQTYPRKLDFTIXXXXXXXXXXXHKICTDIRILANMKEIEEPFDSDQDGSSAMPYKRNPMRCERICSLARHVMTQCFNPLMTASIQWMERTLDDSANRRICIPEAFLATDGMLMTFDNVSAGLVVYQRMIEQHITAELPFMSTEAILVKMVQMGEDRQV 1968
            +++VEELD  V+  AGF   +LVTGQTY RK+D   LS LA L A++HKICTDIR+LAN+KEIEEPF+ +Q GSSAMPYKRNPMR ER CSLARH++    +PL TA++QW+ERTLDDSANRRI +PE+FL  D +L T  N++ GLVVY ++IE+HI  ELPFM+TE +++ MVQ G +RQV
Sbjct:  214 HDKVEELDRKVTEMAGFKKSYLVTGQTYSRKVDIDSLSVLASLGATVHKICTDIRLLANLKEIEEPFEKEQIGSSAMPYKRNPMRAERCCSLARHLVALVSDPLQTAAVQWLERTLDDSANRRISLPESFLTADIILSTLQNITEGLVVYPKVIERHIRHELPFMATENLIMAMVQAGGNRQV 396
[Close]
BLAST of Adenylosuccinate lyase vs. Ensembl Yeast
Match: ADE13 (Adenylosuccinate lyase; catalyzes two steps in the 'de novo' purine nucleotide biosynthetic pathway; expression is repressed by adenine and activated by Bas1p and Pho2p; mutations in human ortholog ADSL cause adenylosuccinase deficiency; human ADSL can complement yeast ADE13 null mutant [Source:SGD;Acc:S000004351])

HSP 1 Score: 266.929 bits (681), Expect = 1.739e-80
Identity = 137/272 (50.37%), Postives = 190/272 (69.85%), Query Frame = 1 
Query: 1420 YNQVEELDVLVSAKAGFLHHFLVTGQTYPRKLDFTIXXXXXXXXXXXHKICTDIRILANMKEIEEPFDSDQDGSSAMPYKRNPMRCERICSLARHVMTQCFNPLMTASIQWMERTLDDSANRRICIPEAFLATDGMLMTFDNVSAGLVVYQRMIEQHITAELPFMSTEAILVKMVQMGEDRQVCHEKIKRISQEAAVNVKEYGKGNDFIERLRAEPYFAKIHGDIEEVLNPYNFTGRSAEQVDRFLK----TALKPLDKYKHLFDEKTELKV 2223
            +++VE LD  V+   GF   + VTGQTY RK+D  +L+ L+  AA+ HK+ TDIR+LAN+KE+EEPF+  Q GSSAM YKRNPMRCER+CSLARH+ +   + + TAS+QW ERTLDDSA RRI +P AFL  D +L T  N+S+GLVVY ++IE+ I  ELPFM+TE I++ MV+    RQ  HE+I+ +S +AA  VKE G  ND IER++ + +F  I  +++ +L P  F GR+ +QV++F++     AL+P  KY  L DE+ +L V
Sbjct:  213 HDKVEALDERVTELLGFDKVYPVTGQTYSRKIDIDVLAPLSSFAATAHKMATDIRLLANLKEVEEPFEKSQIGSSAMAYKRNPMRCERVCSLARHLGSLFSDAVQTASVQWFERTLDDSAIRRISLPSAFLTADILLSTLLNISSGLVVYPKVIERRIKGELPFMATENIIMAMVEKNASRQEVHERIRVLSHQAAAVVKEEGGENDLIERVKRDEFFKPIWEELDSLLEPSTFVGRAPQQVEKFVQKDVNNALQPFQKY--LNDEQVKLNV 482
[Close]
BLAST of Adenylosuccinate lyase vs. Ensembl Nematostella
Match: EDO44892 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RUF4])

HSP 1 Score: 283.493 bits (724), Expect = 4.532e-86
Identity = 146/269 (54.28%), Postives = 189/269 (70.26%), Query Frame = 1 
Query: 1420 YNQVEELDVLVSAKAGFLHHFLVTGQTYPRKLDFTIXXXXXXXXXXXHKICTDIRILANMKEIEEPFDSDQDGSSAMPYKRNPMRCERICSLARHVMTQCFNPLMTASIQWMERTLDDSANRRICIPEAFLATDGMLMTFDNVSAGLVVYQRMIEQHITAELPFMSTEAILVKMVQMGEDRQVCHEKIKRISQEAAVNVKEYGKGNDFIERLRAEPYFAKIHGDIEEVLNPYNFTGRSAEQVDRFLKTALKP-LDKYKHLFDEKTELKV 2223
            + +VE LD LV+  AGF   ++VTGQTY RK+D   L+AL+ L AS+HKICTDIR+LAN KEIEEPF+ DQ GSSAMPYKRNPMR ER CSLARH+MT       TAS+QW+ERTLDDSANRRI + E FL  D +L T  NV  GLVVY ++I +HI  ELPFM+TE +++ MV+ GE RQ CHEK++ +S EA   VKE+G+ ND + R++   YFA IH  + ++L+   F GR+ EQV +FL+   +P L  +      K+E+ V
Sbjct:  215 HGKVERLDELVTEMAGFKLTYIVTGQTYSRKVDLDCLAALSSLGASVHKICTDIRLLANRKEIEEPFEKDQIGSSAMPYKRNPMRSERCCSLARHLMTLVSGAQQTASVQWLERTLDDSANRRIILAEGFLTADIVLSTLQNVFEGLVVYPKVINRHIMQELPFMATENVIMAMVKAGESRQECHEKMRVLSYEAGAQVKEHGRDNDLVARIKECDYFAPIHDHLGDLLDAKTFIGRAPEQVTKFLEIEARPALQPFHAQLHGKSEIDV 483
[Close]
BLAST of Adenylosuccinate lyase vs. Ensembl Medaka
Match: adsl (adenylosuccinate lyase [Source:NCBI gene;Acc:111947783])

HSP 1 Score: 308.531 bits (789), Expect = 4.301e-95
Identity = 154/269 (57.25%), Postives = 204/269 (75.84%), Query Frame = 1 
Query: 1420 YNQVEELDVLVSAKAGFLHHFLVTGQTYPRKLDFTIXXXXXXXXXXXHKICTDIRILANMKEIEEPFDSDQDGSSAMPYKRNPMRCERICSLARHVMTQCFNPLMTASIQWMERTLDDSANRRICIPEAFLATDGMLMTFDNVSAGLVVYQRMIEQHITAELPFMSTEAILVKMVQMGEDRQVCHEKIKRISQEAAVNVKEYGKGNDFIERLRAEPYFAKIHGDIEEVLNPYNFTGRSAEQVDRFLKTALKP-LDKYKHLFDEKTELKV 2223
            +++VEELD +V+  AGF   +LVTGQTY RK+D   LS+LA L AS+HKICTDIR+LAN+KEIEEPF+ +Q GSSAMPYKRNPMR ER CSLARH++    +PL TAS+QW+ERTLDDSANRRI +PE+FL  D +L T  N++ GLVVY ++IE+HI  ELPFM+TE I++ MVQ G +RQ CHEKI+ +SQEAA  VK+ G+ ND + R++ +PYF  I G ++ +L+P  F GR+ +QV RFL   ++P L+ +K   D K EL++
Sbjct:  213 HDKVEELDRMVTEMAGFKKAYLVTGQTYSRKVDVDSLSSLASLGASVHKICTDIRLLANLKEIEEPFEKEQIGSSAMPYKRNPMRAERCCSLARHLVALMADPLQTASVQWLERTLDDSANRRISLPESFLTADIILSTLQNITEGLVVYPKVIERHIRHELPFMATENIIMAMVQAGGNRQDCHEKIRVLSQEAAAVVKQEGRDNDLLARVQQDPYFTPILGQLDALLDPKTFIGRAPQQVTRFLSEEIRPLLEPFKAKMDVKIELEL 481
[Close]
BLAST of Adenylosuccinate lyase vs. Planmine SMEST
Match: SMESG000014474.1 (SMESG000014474.1)

HSP 1 Score: 533.487 bits (1373), Expect = 0.000e+0
Identity = 265/268 (98.88%), Postives = 267/268 (99.63%), Query Frame = 1 
Query: 1420 YNQVEELDVLVSAKAGFLHHFLVTGQTYPRKLDFTIXXXXXXXXXXXHKICTDIRILANMKEIEEPFDSDQDGSSAMPYKRNPMRCERICSLARHVMTQCFNPLMTASIQWMERTLDDSANRRICIPEAFLATDGMLMTFDNVSAGLVVYQRMIEQHITAELPFMSTEAILVKMVQMGEDRQVCHEKIKRISQEAAVNVKEYGKGNDFIERLRAEPYFAKIHGDIEEVLNPYNFTGRSAEQVDRFLKTALKPLDKYKHLFDEKTELKV 2223
            + +VEELDVLVSAKAGFLHHFLVTGQTYPRKLDFTILSALAGLAASLHKICTDIRILANMKEIEEPFDSDQDGSSAMPYKRNPMRCERICSLARHVMTQCFNPLMTASIQWMERTLDDSANRRICIPEAFLATDGMLMTFDNVSAGLVVYQRMIEQHITAELPFMSTEAILVKMVQMGEDRQVCHEKIKRISQEAAVNVKEYGKGNDFIERLRAEPYFAKIHGDIEEVLNPYNFTGRSAEQVDRFLKTALKPLDKYKHLFDEKTELKV
Sbjct:  211 HEKVEELDVLVSAKAGFLHHFLVTGQTYPRKLDFTILSALAGLAASLHKICTDIRILANMKEIEEPFDSDQDGSSAMPYKRNPMRCERICSLARHVMTQCFNPLMTASIQWMERTLDDSANRRICIPEAFLATDGMLMTFDNVSAGLVVYQRMIEQHITAELPFMSTEAILVKMVQMGEDRQVCHEKIKRISQEAAVNVKEYGKGNDFIERLRAEPYFAKIHGDIEEVLNPYNFTGRSAEQVDRFLKTALKPLDKYKHLFDEKTELKV 478
[Close]
BLAST of Adenylosuccinate lyase vs. Planmine SMEST
Match: SMESG000014474.1 (SMESG000014474.1)

HSP 1 Score: 524.242 bits (1349), Expect = 4.341e-178
Identity = 265/279 (94.98%), Postives = 267/279 (95.70%), Query Frame = 1 
Query: 1420 YNQVEELDVLVSAKAGFLHHFLVTGQTYPRKLDFTIXXXXXXXXXXXHKICTDIRILANMKEIEEPFDSDQD-----------GSSAMPYKRNPMRCERICSLARHVMTQCFNPLMTASIQWMERTLDDSANRRICIPEAFLATDGMLMTFDNVSAGLVVYQRMIEQHITAELPFMSTEAILVKMVQMGEDRQVCHEKIKRISQEAAVNVKEYGKGNDFIERLRAEPYFAKIHGDIEEVLNPYNFTGRSAEQVDRFLKTALKPLDKYKHLFDEKTELKV 2223
            + +VEELDVLVSAKAGFLHHFLVTGQTYPRKLDFTILSALAGLAASLHKICTDIRILANMKEIEEPFDSDQD           GSSAMPYKRNPMRCERICSLARHVMTQCFNPLMTASIQWMERTLDDSANRRICIPEAFLATDGMLMTFDNVSAGLVVYQRMIEQHITAELPFMSTEAILVKMVQMGEDRQVCHEKIKRISQEAAVNVKEYGKGNDFIERLRAEPYFAKIHGDIEEVLNPYNFTGRSAEQVDRFLKTALKPLDKYKHLFDEKTELKV
Sbjct:  211 HEKVEELDVLVSAKAGFLHHFLVTGQTYPRKLDFTILSALAGLAASLHKICTDIRILANMKEIEEPFDSDQDAFGDVVDYWPDGSSAMPYKRNPMRCERICSLARHVMTQCFNPLMTASIQWMERTLDDSANRRICIPEAFLATDGMLMTFDNVSAGLVVYQRMIEQHITAELPFMSTEAILVKMVQMGEDRQVCHEKIKRISQEAAVNVKEYGKGNDFIERLRAEPYFAKIHGDIEEVLNPYNFTGRSAEQVDRFLKTALKPLDKYKHLFDEKTELKV 489
The following BLAST results are available for this feature:
BLAST of Adenylosuccinate lyase vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ADSL1.756e-9558.27adenylosuccinate lyase [Source:HGNC Symbol;Acc:HGN... [more]
ADSL1.970e-9558.27adenylosuccinate lyase [Source:HGNC Symbol;Acc:HGN... [more]
ADSL1.688e-9459.45adenylosuccinate lyase [Source:HGNC Symbol;Acc:HGN... [more]
ADSL2.015e-9459.45adenylosuccinate lyase [Source:HGNC Symbol;Acc:HGN... [more]
ADSL6.427e-9455.36adenylosuccinate lyase [Source:HGNC Symbol;Acc:HGN... [more]
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BLAST of Adenylosuccinate lyase vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 3
Match NameE-valueIdentityDescription
adsl-12.461e-5039.69Adenylosuccinate lyase [Source:UniProtKB/Swiss-Pr... [more]
adsl-12.461e-5039.69Adenylosuccinate lyase [Source:UniProtKB/Swiss-Pr... [more]
adsl-16.752e-3448.20Adenylosuccinate lyase [Source:UniProtKB/Swiss-Pr... [more]
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BLAST of Adenylosuccinate lyase vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 1
Match NameE-valueIdentityDescription
AdSL1.359e-8153.18gene:FBgn0038467 transcript:FBtr0083373[more]
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BLAST of Adenylosuccinate lyase vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 3
Match NameE-valueIdentityDescription
adsl2.072e-9757.62adenylosuccinate lyase [Source:ZFIN;Acc:ZDB-GENE-0... [more]
adsl7.728e-9456.00adenylosuccinate lyase [Source:ZFIN;Acc:ZDB-GENE-0... [more]
adsl1.185e-9356.00adenylosuccinate lyase [Source:ZFIN;Acc:ZDB-GENE-0... [more]
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BLAST of Adenylosuccinate lyase vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
adsl7.009e-9758.05adenylosuccinate lyase [Source:NCBI gene;Acc:44805... [more]
adsl2.137e-9657.62adenylosuccinate lyase [Source:NCBI gene;Acc:44805... [more]
adsl3.285e-9657.62adenylosuccinate lyase [Source:NCBI gene;Acc:44805... [more]
adsl4.023e-9259.11adenylosuccinate lyase [Source:NCBI gene;Acc:44805... [more]
adsl6.030e-9258.89adenylosuccinate lyase [Source:NCBI gene;Acc:44805... [more]
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BLAST of Adenylosuccinate lyase vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Adsl6.861e-9758.80adenylosuccinate lyase [Source:MGI Symbol;Acc:MGI:... [more]
Adsl1.035e-9658.80adenylosuccinate lyase [Source:MGI Symbol;Acc:MGI:... [more]
Adsl5.648e-6863.39adenylosuccinate lyase [Source:MGI Symbol;Acc:MGI:... [more]
Adsl5.309e-3567.01adenylosuccinate lyase [Source:MGI Symbol;Acc:MGI:... [more]
Adsl8.396e-1171.43adenylosuccinate lyase [Source:MGI Symbol;Acc:MGI:... [more]
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BLAST of Adenylosuccinate lyase vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|P21265|PUR8_CHICK9.786e-10059.48Adenylosuccinate lyase OS=Gallus gallus OX=9031 GN... [more]
sp|P54822|PUR8_MOUSE7.243e-9658.80Adenylosuccinate lyase OS=Mus musculus OX=10090 GN... [more]
sp|Q8HXY5|PUR8_MACFA1.779e-9558.65Adenylosuccinate lyase OS=Macaca fascicularis OX=9... [more]
sp|P30566|PUR8_HUMAN9.460e-9558.27Adenylosuccinate lyase OS=Homo sapiens OX=9606 GN=... [more]
sp|A3KN12|PUR8_BOVIN2.707e-9457.09Adenylosuccinate lyase OS=Bos taurus OX=9913 GN=AD... [more]
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BLAST of Adenylosuccinate lyase vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A091TLB31.710e-10060.22Adenylosuccinate lyase (Fragment) OS=Pelecanus cri... [more]
A0A094ME251.352e-9959.85Adenylosuccinate lyase (Fragment) OS=Antrostomus c... [more]
G3W6105.437e-9960.22Adenylosuccinate lyase OS=Sarcophilus harrisii OX=... [more]
A0A0A0A2J89.602e-9960.22Adenylosuccinate lyase (Fragment) OS=Charadrius vo... [more]
A0A093H8I51.249e-9860.22Adenylosuccinate lyase (Fragment) OS=Struthio came... [more]
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BLAST of Adenylosuccinate lyase vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 2
Match NameE-valueIdentityDescription
adsl1.608e-9456.88adenylosuccinate lyase [Source:NCBI gene;Acc:10302... [more]
adsl5.186e-6762.30adenylosuccinate lyase [Source:NCBI gene;Acc:10302... [more]
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BLAST of Adenylosuccinate lyase vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Adenylosuccinate lyase vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1
Match NameE-valueIdentityDescription
ADE131.739e-8050.37Adenylosuccinate lyase; catalyzes two steps in the... [more]
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BLAST of Adenylosuccinate lyase vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1
Match NameE-valueIdentityDescription
EDO448924.532e-8654.28Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Adenylosuccinate lyase vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 1
Match NameE-valueIdentityDescription
adsl4.301e-9557.25adenylosuccinate lyase [Source:NCBI gene;Acc:11194... [more]
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BLAST of Adenylosuccinate lyase vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 2
Match NameE-valueIdentityDescription
SMESG000014474.10.000e+098.88SMESG000014474.1[more]
SMESG000014474.14.341e-17894.98SMESG000014474.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30017371 ID=SMED30017371|Name=Adenylosuccinate lyase|organism=Schmidtea mediterranea sexual|type=transcript|length=2714bp
TATTTTTATTATTATTATTATTTTAGAAGAAATATTGTACAAAGGATAGA
ATTAACCTATTACTTACTAGTATGCCAAAATTGTAGTGTGAAGATCAGAA
GTTGGGTATTATTTAAGTATGCTTGTGTGTCTGGATGGTGAATAGATATA
ATGTTTGTCACGGGTACTCTTACTCCATTCCCCCCGTGTGCTGCCGTGAA
TGCAGCCTGTTATGCCGTCTCCCACTGGTAATTGGCAATCGATATTTGCC
GAATGCCCCTCTAATATGCTCACCTGCCCAATTAATCCCCGGCTTATTGG
ATTATTAGAAATCCTCACTCATCGCCACTTAACAAATGCTACAAAGTGTG
ATTTATTTCATATTTTCAGAATAATGAATGTCACGGTTCCGATAAGGTAT
ATTTGTGCTCGCTTATGGTGCCGACTAGTTGCACAATGCACTCGCGTTGC
TAGCACATTAAATCAGCGGTTATATTCTCGTAATTCGTTTCACCCGCCCC
TTCGAGTCACTCGTATTTGCTCCGTCACTGCTGCACATTTAACATGCTCA
CTGATTAATTTTCAATTGATATTAAATAAGGATTTCTAAAATAAAATTTG
TGAAACACAATATTCAGATCTTCAATTTCTTTTTTAAATATATCCGGAAC
CATTTCCAGTAATCTGTTGATATTTCACCTCATTTCCAGTAACCTGTAAC
CATATTCCAAATTTCTAAAATAATAAAGTTTTTTAAGTGAATCTTAATTA
AAATGCTCCTTGGTGTTTCTCTCGTATCAACAGAAAGATGGGATGCGATA
AAGCGCTTGAAATATCCACAAATTGCATATTTTCTAAATCGAAAATGCCC
GTAATCAGTGATTGCTGTCCATAATTTGTGTCCGCCTGTGTGCATTTTAT
TATAGGATTATGTTTGTGTTTGTTATTTTCCGACCAAAATTGTTATTCTA
TATCGTAAATGCCCTTAATTTATACCTATTGCCCATAATCCGTTTCCTTA
TTCCAAGTAGTGATGTAACCTAACCTAGATTTATTATCTCATATAGTTGA
CCTTAATTTGTGGCTGATTGTCCGTAATTAATGCGCTTTGTTGTATTTGT
GAGCCACCTCAATTTCCCAGGTGCCAGTCAAGGATTGACCTATATCCAAC
GTGGCACATTATACATCCATATTAAATTATTGATGGAAAGGAATAGCAAA
CCAAAATCGATAATTATAATGTAATTTCTAAATCTAGGAATATAAGTGAT
TGATAATATCGAATTTTCACTTGCTAGCTGTGCTTTCTATAGGTTTACCA
ATGTAAAATCAATTCTAGAATTCCATCTCAGAGATACAAAACTCAATTAT
TTTCACCATTACCTCTTTTTTATCTTTATAATTTGTATTTCGACCTCGAT
AACGCGAAATTATGTATTCTATAATCAGGTCGAGGAGTTGGACGTTCTTG
TTAGTGCTAAGGCTGGGTTTCTTCACCATTTCCTGGTAACCGGGCAAACT
TATCCTCGTAAATTGGACTTTACCATTCTGTCAGCGCTGGCTGGCCTTGC
AGCCTCGCTGCACAAAATATGCACCGATATCCGAATACTGGCCAATATGA
AGGAAATTGAAGAGCCGTTTGATTCTGATCAGGATGGGTCTAGTGCTATG
CCGTATAAGCGTAACCCAATGCGATGTGAGCGCATCTGTTCTCTTGCTAG
ACATGTAATGACCCAGTGTTTTAACCCGTTGATGACCGCGTCCATCCAAT
GGATGGAACGCACATTGGATGACTCTGCCAATCGCAGGATTTGCATTCCG
GAAGCATTTCTAGCCACTGACGGTATGCTGATGACATTTGATAATGTTTC
AGCTGGACTCGTCGTTTATCAAAGGATGATCGAGCAACATATAACCGCGG
AATTGCCCTTCATGTCGACTGAAGCCATTTTAGTGAAAATGGTTCAAATG
GGCGAGGATCGGCAGGTTTGCCATGAGAAAATCAAACGAATTAGTCAAGA
AGCAGCAGTGAATGTCAAGGAGTACGGTAAAGGGAACGACTTCATTGAAC
GACTGCGTGCTGAGCCATATTTTGCCAAAATCCATGGAGATATTGAAGAG
GTATTGAATCCGTATAATTTCACTGGGCGATCAGCGGAACAAGTTGATCG
GTTCCTCAAGACCGCCTTGAAACCATTGGACAAATATAAACATCTGTTCG
ATGAGAAAACCGAATTGAAAGTTTAGTCAAGGAAGCAACTTAGCAGCACC
CAGTTGGATTCTGGCAAAAATTTAGTTTTTTATTTCAAATTTGTAATCCT
GTTGAAATTTGTGTACATTTTTTGATAATCTGAATTTAGTAAATTGTTTG
TTGACTTTTATTGATTTGTTTTTATTATCGATTGTTGTTCGGTGTTTCAT
ATTGATTATTGGGATTTAATGTTGATCGATTTTTGAATTTGATTTAGTCC
CTAGTTGGATTTAATTTGTACATAACTGAATTAGTACTCAGTGAAATTAA
TTTTCTTGCAATAGCTATCATATCAAAGGCCACGATTTCACCAAACCAGA
AGTTTAACAATTCTGCTATATAAACTTATAGATTATTGGTACATATGTGG
CAGTTGTCTCAAAGTAATTTGTTTTTAATTGTGAATTTAAAATATTGGAA
ACTTGGGTGTTAATTGCATTATTAATCTTGGTATTTGTTGGAATTTATAA
TACGTGATCGAAAG
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protein sequence of SMED30017371-orf-1

>SMED30017371-orf-1 ID=SMED30017371-orf-1|Name=SMED30017371-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=130bp
MQPVMPSPTGNWQSIFAECPSNMLTCPINPRLIGLLEILTHRHLTNATKC
DLFHIFRIMNVTVPIRYICARLWCRLVAQCTRVASTLNQRLYSRNSFHPP
LRVTRICSVTAAHLTCSLINFQLILNKDF*
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protein sequence of SMED30017371-orf-2

>SMED30017371-orf-2 ID=SMED30017371-orf-2|Name=SMED30017371-orf-2|organism=Schmidtea mediterranea sexual|type=polypeptide|length=210bp
MKEIEEPFDSDQDGSSAMPYKRNPMRCERICSLARHVMTQCFNPLMTASI
QWMERTLDDSANRRICIPEAFLATDGMLMTFDNVSAGLVVYQRMIEQHIT
AELPFMSTEAILVKMVQMGEDRQVCHEKIKRISQEAAVNVKEYGKGNDFI
ERLRAEPYFAKIHGDIEEVLNPYNFTGRSAEQVDRFLKTALKPLDKYKHL
FDEKTELKV*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000020protonephridia
PLANA:0000429neoblast
PLANA:0002109X1 cell
PLANA:0002111X2 cell
Vocabulary: INTERPRO
TermDefinition
IPR000362Fumarate_lyase_fam
IPR019468AdenyloSucc_lyase_C
IPR022761Fumarate_lyase_N
IPR020557Fumarate_lyase_CS
IPR008948L-Aspartase-like
Vocabulary: molecular function
TermDefinition
GO:0003824catalytic activity
GO:0004018N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity
GO:0016829lyase activity
GO:0070626(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity
Vocabulary: cellular component
TermDefinition
GO:0005829cytosol
Vocabulary: biological process
TermDefinition
GO:0006164purine nucleotide biosynthetic process
GO:0006189'de novo' IMP biosynthetic process
GO:0009152purine ribonucleotide biosynthetic process
GO:0044208'de novo' AMP biosynthetic process
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR019468Adenylosuccinate lyase C-terminalSMARTSM00998ADSL_C_2coord: 103..187
e-value: 4.9E-20
score: 82.6
IPR019468Adenylosuccinate lyase C-terminalPFAMPF10397ADSL_Ccoord: 104..186
e-value: 2.3E-14
score: 53.7
NoneNo IPR availableGENE3DG3DSA:1.20.200.10coord: 1..101
e-value: 1.2E-34
score: 121.7
NoneNo IPR availableGENE3DG3DSA:1.10.40.30coord: 102..175
e-value: 1.3E-21
score: 78.2
NoneNo IPR availablePANTHERPTHR43172FAMILY NOT NAMEDcoord: 1..195
IPR022761Fumarate lyase, N-terminalPFAMPF00206Lyase_1coord: 4..38
e-value: 1.2E-5
score: 24.8
IPR020557Fumarate lyase, conserved sitePROSITEPS00163FUMARATE_LYASEScoord: 14..23
IPR008948L-Aspartase-likeSUPERFAMILYSSF48557L-aspartase-likecoord: 2..188