Disabled 2-interacting protein
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30017369 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 10
Homology
BLAST of Disabled 2-interacting protein vs. Ensembl Human
Match: DAB2IP (DAB2 interacting protein [Source:HGNC Symbol;Acc:HGNC:17294]) HSP 1 Score: 302.753 bits (774), Expect = 7.416e-85 Identity = 178/446 (39.91%), Postives = 251/446 (56.28%), Query Frame = 3
Query: 861 CLSQPEMNEWLTKIKQRINPNYKNSTRHEDLLQIWIQEAKQLIQKKRYYCEIKLDEMLYGRTTIKTVTDTVFWGEEFEFRGLQNINKITICLYKMTDNKKKHERSELVAQIEVPCADLTDSSPCEKWYSPPFQYSNLRLSQSELTNSQKVKLDELLKNAVDIAPMIRIKGRYRPLEILPNKFYDSLSDFLVKQSIPLVESLESHLKVKSKEDFVKILLVILKSKDCHIDFLADLVFIEVSKAEDN--LILRGNSIASKAMECYLKMVGEKYLATILKDLINEVIFEEIDCEVDPLRLNNSKENSQIFENQNKLLRLVENVWSKIYHNAHLIPNELKLVFTKIREKLSETKRGSSYSSPMIYQ-VISSCLFLRFICPAIMSPFLFGLSNEYPDNVSINRTFTLIAKSIQSLANFSQFPQSKETYMEFMQNFINKNSSSMRSFLKLIS 2189
C S E ++W+ +++ ++PN NS R E +L++W+ EAK L KK+Y CE+ LD++LY RTT K TD VFWGE FEF L + +T+ LY+ TD KKK ER+ + + +P A + EKWY P N K PMIRIK RY+ + ILP + Y ++ + + L +LE L K+KE+ L+ IL+S DFL DL+ EV + DN LI R N++A+KA+E YLK+VG+KYL L + I + + +CEVDP + + + + E+Q L E + KI ++ + P ELK VF R++ S R P I + +IS+ LFLRF+CPAIMSP LF L EYPD+ + RT TLIAK Q+LANF++F SKE YM FM F+ ++M+ FL IS
Sbjct: 60 CRSAAERDKWMENLRRAVHPNKDNSRRVEHILKLWVIEAKDLPAKKKYLCELCLDDVLYARTTGKLKTDNVFWGEHFEFHNLPPLRTVTVHLYRETDKKKKKERNSYLGLVSLPAASVAGRQFVEKWY--PVVTPNP-------------------KGGKGPGPMIRIKARYQTITILPMEMYKEFAEHITNHYLGLCAALEPILSAKTKEEMASALVHILQSTGKVKDFLTDLMMSEVDRCGDNEHLIFRENTLATKAIEEYLKLVGQKYLQDALGEFIKALYESDENCEVDPSKCS----AADLPEHQGNLKMCCELAFCKIINSYCVFPRELKEVFASWRQECSSRGR------PDISERLISASLFLRFLCPAIMSPSLFNLLQEYPDDRTA-RTLTLIAKVTQNLANFAKF-GSKEEYMSFMNQFLEHEWTNMQRFLLEIS 472
BLAST of Disabled 2-interacting protein vs. Ensembl Human
Match: DAB2IP (DAB2 interacting protein [Source:HGNC Symbol;Acc:HGNC:17294]) HSP 1 Score: 302.753 bits (774), Expect = 8.348e-85 Identity = 178/446 (39.91%), Postives = 251/446 (56.28%), Query Frame = 3
Query: 861 CLSQPEMNEWLTKIKQRINPNYKNSTRHEDLLQIWIQEAKQLIQKKRYYCEIKLDEMLYGRTTIKTVTDTVFWGEEFEFRGLQNINKITICLYKMTDNKKKHERSELVAQIEVPCADLTDSSPCEKWYSPPFQYSNLRLSQSELTNSQKVKLDELLKNAVDIAPMIRIKGRYRPLEILPNKFYDSLSDFLVKQSIPLVESLESHLKVKSKEDFVKILLVILKSKDCHIDFLADLVFIEVSKAEDN--LILRGNSIASKAMECYLKMVGEKYLATILKDLINEVIFEEIDCEVDPLRLNNSKENSQIFENQNKLLRLVENVWSKIYHNAHLIPNELKLVFTKIREKLSETKRGSSYSSPMIYQ-VISSCLFLRFICPAIMSPFLFGLSNEYPDNVSINRTFTLIAKSIQSLANFSQFPQSKETYMEFMQNFINKNSSSMRSFLKLIS 2189
C S E ++W+ +++ ++PN NS R E +L++W+ EAK L KK+Y CE+ LD++LY RTT K TD VFWGE FEF L + +T+ LY+ TD KKK ER+ + + +P A + EKWY P N K PMIRIK RY+ + ILP + Y ++ + + L +LE L K+KE+ L+ IL+S DFL DL+ EV + DN LI R N++A+KA+E YLK+VG+KYL L + I + + +CEVDP + + + + E+Q L E + KI ++ + P ELK VF R++ S R P I + +IS+ LFLRF+CPAIMSP LF L EYPD+ + RT TLIAK Q+LANF++F SKE YM FM F+ ++M+ FL IS
Sbjct: 93 CRSAAERDKWMENLRRAVHPNKDNSRRVEHILKLWVIEAKDLPAKKKYLCELCLDDVLYARTTGKLKTDNVFWGEHFEFHNLPPLRTVTVHLYRETDKKKKKERNSYLGLVSLPAASVAGRQFVEKWY--PVVTPNP-------------------KGGKGPGPMIRIKARYQTITILPMEMYKEFAEHITNHYLGLCAALEPILSAKTKEEMASALVHILQSTGKVKDFLTDLMMSEVDRCGDNEHLIFRENTLATKAIEEYLKLVGQKYLQDALGEFIKALYESDENCEVDPSKCS----AADLPEHQGNLKMCCELAFCKIINSYCVFPRELKEVFASWRQECSSRGR------PDISERLISASLFLRFLCPAIMSPSLFNLLQEYPDDRTA-RTLTLIAKVTQNLANFAKF-GSKEEYMSFMNQFLEHEWTNMQRFLLEIS 505
BLAST of Disabled 2-interacting protein vs. Ensembl Human
Match: DAB2IP (DAB2 interacting protein [Source:HGNC Symbol;Acc:HGNC:17294]) HSP 1 Score: 302.753 bits (774), Expect = 1.329e-84 Identity = 178/446 (39.91%), Postives = 251/446 (56.28%), Query Frame = 3
Query: 861 CLSQPEMNEWLTKIKQRINPNYKNSTRHEDLLQIWIQEAKQLIQKKRYYCEIKLDEMLYGRTTIKTVTDTVFWGEEFEFRGLQNINKITICLYKMTDNKKKHERSELVAQIEVPCADLTDSSPCEKWYSPPFQYSNLRLSQSELTNSQKVKLDELLKNAVDIAPMIRIKGRYRPLEILPNKFYDSLSDFLVKQSIPLVESLESHLKVKSKEDFVKILLVILKSKDCHIDFLADLVFIEVSKAEDN--LILRGNSIASKAMECYLKMVGEKYLATILKDLINEVIFEEIDCEVDPLRLNNSKENSQIFENQNKLLRLVENVWSKIYHNAHLIPNELKLVFTKIREKLSETKRGSSYSSPMIYQ-VISSCLFLRFICPAIMSPFLFGLSNEYPDNVSINRTFTLIAKSIQSLANFSQFPQSKETYMEFMQNFINKNSSSMRSFLKLIS 2189
C S E ++W+ +++ ++PN NS R E +L++W+ EAK L KK+Y CE+ LD++LY RTT K TD VFWGE FEF L + +T+ LY+ TD KKK ER+ + + +P A + EKWY P N K PMIRIK RY+ + ILP + Y ++ + + L +LE L K+KE+ L+ IL+S DFL DL+ EV + DN LI R N++A+KA+E YLK+VG+KYL L + I + + +CEVDP + + + + E+Q L E + KI ++ + P ELK VF R++ S R P I + +IS+ LFLRF+CPAIMSP LF L EYPD+ + RT TLIAK Q+LANF++F SKE YM FM F+ ++M+ FL IS
Sbjct: 123 CRSAAERDKWMENLRRAVHPNKDNSRRVEHILKLWVIEAKDLPAKKKYLCELCLDDVLYARTTGKLKTDNVFWGEHFEFHNLPPLRTVTVHLYRETDKKKKKERNSYLGLVSLPAASVAGRQFVEKWY--PVVTPNP-------------------KGGKGPGPMIRIKARYQTITILPMEMYKEFAEHITNHYLGLCAALEPILSAKTKEEMASALVHILQSTGKVKDFLTDLMMSEVDRCGDNEHLIFRENTLATKAIEEYLKLVGQKYLQDALGEFIKALYESDENCEVDPSKCS----AADLPEHQGNLKMCCELAFCKIINSYCVFPRELKEVFASWRQECSSRGR------PDISERLISASLFLRFLCPAIMSPSLFNLLQEYPDDRTA-RTLTLIAKVTQNLANFAKF-GSKEEYMSFMNQFLEHEWTNMQRFLLEIS 535
BLAST of Disabled 2-interacting protein vs. Ensembl Human
Match: DAB2IP (DAB2 interacting protein [Source:HGNC Symbol;Acc:HGNC:17294]) HSP 1 Score: 302.753 bits (774), Expect = 1.616e-84 Identity = 178/446 (39.91%), Postives = 251/446 (56.28%), Query Frame = 3
Query: 861 CLSQPEMNEWLTKIKQRINPNYKNSTRHEDLLQIWIQEAKQLIQKKRYYCEIKLDEMLYGRTTIKTVTDTVFWGEEFEFRGLQNINKITICLYKMTDNKKKHERSELVAQIEVPCADLTDSSPCEKWYSPPFQYSNLRLSQSELTNSQKVKLDELLKNAVDIAPMIRIKGRYRPLEILPNKFYDSLSDFLVKQSIPLVESLESHLKVKSKEDFVKILLVILKSKDCHIDFLADLVFIEVSKAEDN--LILRGNSIASKAMECYLKMVGEKYLATILKDLINEVIFEEIDCEVDPLRLNNSKENSQIFENQNKLLRLVENVWSKIYHNAHLIPNELKLVFTKIREKLSETKRGSSYSSPMIYQ-VISSCLFLRFICPAIMSPFLFGLSNEYPDNVSINRTFTLIAKSIQSLANFSQFPQSKETYMEFMQNFINKNSSSMRSFLKLIS 2189
C S E ++W+ +++ ++PN NS R E +L++W+ EAK L KK+Y CE+ LD++LY RTT K TD VFWGE FEF L + +T+ LY+ TD KKK ER+ + + +P A + EKWY P N K PMIRIK RY+ + ILP + Y ++ + + L +LE L K+KE+ L+ IL+S DFL DL+ EV + DN LI R N++A+KA+E YLK+VG+KYL L + I + + +CEVDP + + + + E+Q L E + KI ++ + P ELK VF R++ S R P I + +IS+ LFLRF+CPAIMSP LF L EYPD+ + RT TLIAK Q+LANF++F SKE YM FM F+ ++M+ FL IS
Sbjct: 156 CRSAAERDKWMENLRRAVHPNKDNSRRVEHILKLWVIEAKDLPAKKKYLCELCLDDVLYARTTGKLKTDNVFWGEHFEFHNLPPLRTVTVHLYRETDKKKKKERNSYLGLVSLPAASVAGRQFVEKWY--PVVTPNP-------------------KGGKGPGPMIRIKARYQTITILPMEMYKEFAEHITNHYLGLCAALEPILSAKTKEEMASALVHILQSTGKVKDFLTDLMMSEVDRCGDNEHLIFRENTLATKAIEEYLKLVGQKYLQDALGEFIKALYESDENCEVDPSKCS----AADLPEHQGNLKMCCELAFCKIINSYCVFPRELKEVFASWRQECSSRGR------PDISERLISASLFLRFLCPAIMSPSLFNLLQEYPDDRTA-RTLTLIAKVTQNLANFAKF-GSKEEYMSFMNQFLEHEWTNMQRFLLEIS 568
BLAST of Disabled 2-interacting protein vs. Ensembl Human
Match: DAB2IP (DAB2 interacting protein [Source:HGNC Symbol;Acc:HGNC:17294]) HSP 1 Score: 303.138 bits (775), Expect = 1.910e-84 Identity = 178/446 (39.91%), Postives = 251/446 (56.28%), Query Frame = 3
Query: 861 CLSQPEMNEWLTKIKQRINPNYKNSTRHEDLLQIWIQEAKQLIQKKRYYCEIKLDEMLYGRTTIKTVTDTVFWGEEFEFRGLQNINKITICLYKMTDNKKKHERSELVAQIEVPCADLTDSSPCEKWYSPPFQYSNLRLSQSELTNSQKVKLDELLKNAVDIAPMIRIKGRYRPLEILPNKFYDSLSDFLVKQSIPLVESLESHLKVKSKEDFVKILLVILKSKDCHIDFLADLVFIEVSKAEDN--LILRGNSIASKAMECYLKMVGEKYLATILKDLINEVIFEEIDCEVDPLRLNNSKENSQIFENQNKLLRLVENVWSKIYHNAHLIPNELKLVFTKIREKLSETKRGSSYSSPMIYQ-VISSCLFLRFICPAIMSPFLFGLSNEYPDNVSINRTFTLIAKSIQSLANFSQFPQSKETYMEFMQNFINKNSSSMRSFLKLIS 2189
C S E ++W+ +++ ++PN NS R E +L++W+ EAK L KK+Y CE+ LD++LY RTT K TD VFWGE FEF L + +T+ LY+ TD KKK ER+ + + +P A + EKWY P N K PMIRIK RY+ + ILP + Y ++ + + L +LE L K+KE+ L+ IL+S DFL DL+ EV + DN LI R N++A+KA+E YLK+VG+KYL L + I + + +CEVDP + + + + E+Q L E + KI ++ + P ELK VF R++ S R P I + +IS+ LFLRF+CPAIMSP LF L EYPD+ + RT TLIAK Q+LANF++F SKE YM FM F+ ++M+ FL IS
Sbjct: 184 CRSAAERDKWMENLRRAVHPNKDNSRRVEHILKLWVIEAKDLPAKKKYLCELCLDDVLYARTTGKLKTDNVFWGEHFEFHNLPPLRTVTVHLYRETDKKKKKERNSYLGLVSLPAASVAGRQFVEKWY--PVVTPNP-------------------KGGKGPGPMIRIKARYQTITILPMEMYKEFAEHITNHYLGLCAALEPILSAKTKEEMASALVHILQSTGKVKDFLTDLMMSEVDRCGDNEHLIFRENTLATKAIEEYLKLVGQKYLQDALGEFIKALYESDENCEVDPSKCS----AADLPEHQGNLKMCCELAFCKIINSYCVFPRELKEVFASWRQECSSRGR------PDISERLISASLFLRFLCPAIMSPSLFNLLQEYPDDRTA-RTLTLIAKVTQNLANFAKF-GSKEEYMSFMNQFLEHEWTNMQRFLLEIS 596
BLAST of Disabled 2-interacting protein vs. Ensembl Celegans
Match: gap-2 (Ras GTPase-activating protein gap-2 [Source:UniProtKB/Swiss-Prot;Acc:Q8MLZ5]) HSP 1 Score: 313.153 bits (801), Expect = 1.100e-89 Identity = 171/452 (37.83%), Postives = 268/452 (59.29%), Query Frame = 3
Query: 861 CLSQPEMNEWLTKIKQRINPNYKNSTRHEDLLQIWIQEAKQLIQKKRYYCEIKLDEMLYGRTTIKTVTDTVFWGEEFEFRGLQNINKITICLYKMTDNKKKHERSELVAQIEVPCADLTDSSPCEKWYSPPFQYSNLRLSQSELTNSQKVKLDELLKNAVDIAPMIRIKGRYRPLEILPNKFYDSLSDFLVKQSIPLVESLESHLKVKSKEDFVKILLVILKSKDCHIDFLADLVFIEVSKAE-DNLILRGNSIASKAMECYLKMVGEKYLATILKDLINEVIFEEIDCEVDPLRLNNSKENSQIFENQNKLLRLVENVWSKIYHNAHLIPNELKLVFTKIREKLSETKRGSSYSSPMIYQVISSCLFLRFICPAIMSPFLFGLSNEYPDNVSINRTFTLIAKSIQSLANFSQFPQSKETYMEFMQNFINKNSSSMRSFLKLISLNKSNGAK 2213
C + E +W+ +++ +NP R E+ + IWI EAK L K++YYCE+ LD+ LY +T+ K TD VFWGE FEF L I+++ + L++ +D+KKK + L+ + + L+ SP E+WY+ +S+ + + ++ K++ +P +RIK R++ + ILP + YD+L + L +PL E LE L V+ KED L+ ++ + +FL DL+ EV K + D+L+ RGN++A+KAME ++K+V + YL + L D I V+ E CEVDP +L N NS + +N+ L+R VE W+KI +N H +P L+ VF+ +R +L R + + +ISS +FLRF+CPAI+SP LF L +EYP + R TLIAK++Q+LANFS+F KE +MEFM F+++ M+ FL IS +G +
Sbjct: 106 CRTPLERAKWMENLRKTMNPRRDQQRRTENSMLIWILEAKGLPAKRKYYCEMTLDKTLYAKTSSKARTDNVFWGENFEFMMLPKIDEVCVSLFRESDSKKK--KDTLIGYVTIGIDQLSSRSPVERWYTVNTSHSD--------SGTSRIASALGGKSSSQESPSLRIKARWQSVHILPLRAYDNLLETLCYNYLPLCEQLEPVLNVRDKEDLATSLVRVMYKHNLAKEFLCDLIMKEVEKLDNDHLMFRGNTLATKAMESFMKLVADDYLDSTLSDFIKTVLQCEDSCEVDPQKLGNVS-NSSLEKNRALLMRYVEVAWTKILNNVHQLPKNLRDVFSALRCRLEAQNREA-----LADTLISSSIFLRFLCPAILSPSLFNLVSEYPSPTNA-RNLTLIAKTLQNLANFSKF-GGKEPHMEFMNEFVDREWHRMKDFLLRISSESKSGPE 539
BLAST of Disabled 2-interacting protein vs. Ensembl Celegans
Match: gap-2 (Ras GTPase-activating protein gap-2 [Source:UniProtKB/Swiss-Prot;Acc:Q8MLZ5]) HSP 1 Score: 313.153 bits (801), Expect = 1.388e-89 Identity = 171/450 (38.00%), Postives = 267/450 (59.33%), Query Frame = 3
Query: 861 CLSQPEMNEWLTKIKQRINPNYKNSTRHEDLLQIWIQEAKQLIQKKRYYCEIKLDEMLYGRTTIKTVTDTVFWGEEFEFRGLQNINKITICLYKMTDNKKKHERSELVAQIEVPCADLTDSSPCEKWYSPPFQYSNLRLSQSELTNSQKVKLDELLKNAVDIAPMIRIKGRYRPLEILPNKFYDSLSDFLVKQSIPLVESLESHLKVKSKEDFVKILLVILKSKDCHIDFLADLVFIEVSKAE-DNLILRGNSIASKAMECYLKMVGEKYLATILKDLINEVIFEEIDCEVDPLRLNNSKENSQIFENQNKLLRLVENVWSKIYHNAHLIPNELKLVFTKIREKLSETKRGSSYSSPMIYQVISSCLFLRFICPAIMSPFLFGLSNEYPDNVSINRTFTLIAKSIQSLANFSQFPQSKETYMEFMQNFINKNSSSMRSFLKLISLNKSNG 2207
C + E +W+ +++ +NP R E+ + IWI EAK L K++YYCE+ LD+ LY +T+ K TD VFWGE FEF L I+++ + L++ +D+KKK + L+ + + L+ SP E+WY+ +S+ + + ++ K++ +P +RIK R++ + ILP + YD+L + L +PL E LE L V+ KED L+ ++ + +FL DL+ EV K + D+L+ RGN++A+KAME ++K+V + YL + L D I V+ E CEVDP +L N NS + +N+ L+R VE W+KI +N H +P L+ VF+ +R +L R + + +ISS +FLRF+CPAI+SP LF L +EYP + R TLIAK++Q+LANFS+F KE +MEFM F+++ M+ FL IS +G
Sbjct: 114 CRTPLERAKWMENLRKTMNPRRDQQRRTENSMLIWILEAKGLPAKRKYYCEMTLDKTLYAKTSSKARTDNVFWGENFEFMMLPKIDEVCVSLFRESDSKKK--KDTLIGYVTIGIDQLSSRSPVERWYTVNTSHSD--------SGTSRIASALGGKSSSQESPSLRIKARWQSVHILPLRAYDNLLETLCYNYLPLCEQLEPVLNVRDKEDLATSLVRVMYKHNLAKEFLCDLIMKEVEKLDNDHLMFRGNTLATKAMESFMKLVADDYLDSTLSDFIKTVLQCEDSCEVDPQKLGNV-SNSSLEKNRALLMRYVEVAWTKILNNVHQLPKNLRDVFSALRCRLEAQNREA-----LADTLISSSIFLRFLCPAILSPSLFNLVSEYPSPTNA-RNLTLIAKTLQNLANFSKF-GGKEPHMEFMNEFVDREWHRMKDFLLRISSESKSG 545
BLAST of Disabled 2-interacting protein vs. Ensembl Celegans
Match: gap-2 (Ras GTPase-activating protein gap-2 [Source:UniProtKB/Swiss-Prot;Acc:Q8MLZ5]) HSP 1 Score: 313.923 bits (803), Expect = 2.863e-89 Identity = 171/450 (38.00%), Postives = 267/450 (59.33%), Query Frame = 3
Query: 861 CLSQPEMNEWLTKIKQRINPNYKNSTRHEDLLQIWIQEAKQLIQKKRYYCEIKLDEMLYGRTTIKTVTDTVFWGEEFEFRGLQNINKITICLYKMTDNKKKHERSELVAQIEVPCADLTDSSPCEKWYSPPFQYSNLRLSQSELTNSQKVKLDELLKNAVDIAPMIRIKGRYRPLEILPNKFYDSLSDFLVKQSIPLVESLESHLKVKSKEDFVKILLVILKSKDCHIDFLADLVFIEVSKAE-DNLILRGNSIASKAMECYLKMVGEKYLATILKDLINEVIFEEIDCEVDPLRLNNSKENSQIFENQNKLLRLVENVWSKIYHNAHLIPNELKLVFTKIREKLSETKRGSSYSSPMIYQVISSCLFLRFICPAIMSPFLFGLSNEYPDNVSINRTFTLIAKSIQSLANFSQFPQSKETYMEFMQNFINKNSSSMRSFLKLISLNKSNG 2207
C + E +W+ +++ +NP R E+ + IWI EAK L K++YYCE+ LD+ LY +T+ K TD VFWGE FEF L I+++ + L++ +D+KKK + L+ + + L+ SP E+WY+ +S+ + + ++ K++ +P +RIK R++ + ILP + YD+L + L +PL E LE L V+ KED L+ ++ + +FL DL+ EV K + D+L+ RGN++A+KAME ++K+V + YL + L D I V+ E CEVDP +L N NS + +N+ L+R VE W+KI +N H +P L+ VF+ +R +L R + + +ISS +FLRF+CPAI+SP LF L +EYP + R TLIAK++Q+LANFS+F KE +MEFM F+++ M+ FL IS +G
Sbjct: 206 CRTPLERAKWMENLRKTMNPRRDQQRRTENSMLIWILEAKGLPAKRKYYCEMTLDKTLYAKTSSKARTDNVFWGENFEFMMLPKIDEVCVSLFRESDSKKK--KDTLIGYVTIGIDQLSSRSPVERWYTVNTSHSD--------SGTSRIASALGGKSSSQESPSLRIKARWQSVHILPLRAYDNLLETLCYNYLPLCEQLEPVLNVRDKEDLATSLVRVMYKHNLAKEFLCDLIMKEVEKLDNDHLMFRGNTLATKAMESFMKLVADDYLDSTLSDFIKTVLQCEDSCEVDPQKLGNVS-NSSLEKNRALLMRYVEVAWTKILNNVHQLPKNLRDVFSALRCRLEAQNREA-----LADTLISSSIFLRFLCPAILSPSLFNLVSEYPSPTNA-RNLTLIAKTLQNLANFSKF-GGKEPHMEFMNEFVDREWHRMKDFLLRISSESKSG 637
BLAST of Disabled 2-interacting protein vs. Ensembl Celegans
Match: gap-2 (Ras GTPase-activating protein gap-2 [Source:UniProtKB/Swiss-Prot;Acc:Q8MLZ5]) HSP 1 Score: 313.923 bits (803), Expect = 5.858e-89 Identity = 171/450 (38.00%), Postives = 267/450 (59.33%), Query Frame = 3
Query: 861 CLSQPEMNEWLTKIKQRINPNYKNSTRHEDLLQIWIQEAKQLIQKKRYYCEIKLDEMLYGRTTIKTVTDTVFWGEEFEFRGLQNINKITICLYKMTDNKKKHERSELVAQIEVPCADLTDSSPCEKWYSPPFQYSNLRLSQSELTNSQKVKLDELLKNAVDIAPMIRIKGRYRPLEILPNKFYDSLSDFLVKQSIPLVESLESHLKVKSKEDFVKILLVILKSKDCHIDFLADLVFIEVSKAE-DNLILRGNSIASKAMECYLKMVGEKYLATILKDLINEVIFEEIDCEVDPLRLNNSKENSQIFENQNKLLRLVENVWSKIYHNAHLIPNELKLVFTKIREKLSETKRGSSYSSPMIYQVISSCLFLRFICPAIMSPFLFGLSNEYPDNVSINRTFTLIAKSIQSLANFSQFPQSKETYMEFMQNFINKNSSSMRSFLKLISLNKSNG 2207
C + E +W+ +++ +NP R E+ + IWI EAK L K++YYCE+ LD+ LY +T+ K TD VFWGE FEF L I+++ + L++ +D+KKK + L+ + + L+ SP E+WY+ +S+ + + ++ K++ +P +RIK R++ + ILP + YD+L + L +PL E LE L V+ KED L+ ++ + +FL DL+ EV K + D+L+ RGN++A+KAME ++K+V + YL + L D I V+ E CEVDP +L N NS + +N+ L+R VE W+KI +N H +P L+ VF+ +R +L R + + +ISS +FLRF+CPAI+SP LF L +EYP + R TLIAK++Q+LANFS+F KE +MEFM F+++ M+ FL IS +G
Sbjct: 246 CRTPLERAKWMENLRKTMNPRRDQQRRTENSMLIWILEAKGLPAKRKYYCEMTLDKTLYAKTSSKARTDNVFWGENFEFMMLPKIDEVCVSLFRESDSKKK--KDTLIGYVTIGIDQLSSRSPVERWYTVNTSHSD--------SGTSRIASALGGKSSSQESPSLRIKARWQSVHILPLRAYDNLLETLCYNYLPLCEQLEPVLNVRDKEDLATSLVRVMYKHNLAKEFLCDLIMKEVEKLDNDHLMFRGNTLATKAMESFMKLVADDYLDSTLSDFIKTVLQCEDSCEVDPQKLGNVS-NSSLEKNRALLMRYVEVAWTKILNNVHQLPKNLRDVFSALRCRLEAQNREA-----LADTLISSSIFLRFLCPAILSPSLFNLVSEYPSPTNA-RNLTLIAKTLQNLANFSKF-GGKEPHMEFMNEFVDREWHRMKDFLLRISSESKSG 677
BLAST of Disabled 2-interacting protein vs. Ensembl Celegans
Match: gap-2 (Ras GTPase-activating protein gap-2 [Source:UniProtKB/Swiss-Prot;Acc:Q8MLZ5]) HSP 1 Score: 313.923 bits (803), Expect = 1.044e-88 Identity = 171/450 (38.00%), Postives = 267/450 (59.33%), Query Frame = 3
Query: 861 CLSQPEMNEWLTKIKQRINPNYKNSTRHEDLLQIWIQEAKQLIQKKRYYCEIKLDEMLYGRTTIKTVTDTVFWGEEFEFRGLQNINKITICLYKMTDNKKKHERSELVAQIEVPCADLTDSSPCEKWYSPPFQYSNLRLSQSELTNSQKVKLDELLKNAVDIAPMIRIKGRYRPLEILPNKFYDSLSDFLVKQSIPLVESLESHLKVKSKEDFVKILLVILKSKDCHIDFLADLVFIEVSKAE-DNLILRGNSIASKAMECYLKMVGEKYLATILKDLINEVIFEEIDCEVDPLRLNNSKENSQIFENQNKLLRLVENVWSKIYHNAHLIPNELKLVFTKIREKLSETKRGSSYSSPMIYQVISSCLFLRFICPAIMSPFLFGLSNEYPDNVSINRTFTLIAKSIQSLANFSQFPQSKETYMEFMQNFINKNSSSMRSFLKLISLNKSNG 2207
C + E +W+ +++ +NP R E+ + IWI EAK L K++YYCE+ LD+ LY +T+ K TD VFWGE FEF L I+++ + L++ +D+KKK + L+ + + L+ SP E+WY+ +S+ + + ++ K++ +P +RIK R++ + ILP + YD+L + L +PL E LE L V+ KED L+ ++ + +FL DL+ EV K + D+L+ RGN++A+KAME ++K+V + YL + L D I V+ E CEVDP +L N NS + +N+ L+R VE W+KI +N H +P L+ VF+ +R +L R + + +ISS +FLRF+CPAI+SP LF L +EYP + R TLIAK++Q+LANFS+F KE +MEFM F+++ M+ FL IS +G
Sbjct: 295 CRTPLERAKWMENLRKTMNPRRDQQRRTENSMLIWILEAKGLPAKRKYYCEMTLDKTLYAKTSSKARTDNVFWGENFEFMMLPKIDEVCVSLFRESDSKKK--KDTLIGYVTIGIDQLSSRSPVERWYTVNTSHSD--------SGTSRIASALGGKSSSQESPSLRIKARWQSVHILPLRAYDNLLETLCYNYLPLCEQLEPVLNVRDKEDLATSLVRVMYKHNLAKEFLCDLIMKEVEKLDNDHLMFRGNTLATKAMESFMKLVADDYLDSTLSDFIKTVLQCEDSCEVDPQKLGNV-SNSSLEKNRALLMRYVEVAWTKILNNVHQLPKNLRDVFSALRCRLEAQNREA-----LADTLISSSIFLRFLCPAILSPSLFNLVSEYPSPTNA-RNLTLIAKTLQNLANFSKF-GGKEPHMEFMNEFVDREWHRMKDFLLRISSESKSG 726
BLAST of Disabled 2-interacting protein vs. Ensembl Fly
Match: raskol (gene:FBgn0261570 transcript:FBtr0302836) HSP 1 Score: 316.62 bits (810), Expect = 5.048e-88 Identity = 162/444 (36.49%), Postives = 264/444 (59.46%), Query Frame = 3
Query: 861 CLSQPEMNEWLTKIKQRINPNYKNSTRHEDLLQIWIQEAKQLIQKKRYYCEIKLDEMLYGRTTIKTVTDTVFWGEEFEFRGLQNINKITICLYKMTDNKKKHERSELVAQIEVPCADLTDSSPCEKWYSPPFQYSNLRLSQSELTNSQKVKLDELLKNAVDIAPMIRIKGRYRPLEILPNKFYDSLSDFLVKQSIPLVESLESHLKVKSKEDFVKILLVILKSKDCHIDFLADLVFIEVSKAEDN-LILRGNSIASKAMECYLKMVGEKYLATILKDLINEVIFEEIDCEVDPLRLNNSKENSQIFENQNKLLRLVENVWSKIYHNAHLIPNELKLVFTKIREKLSETKRGSSYSSPMIYQVISSCLFLRFICPAIMSPFLFGLSNEYPDNVSINRTFTLIAKSIQSLANFSQFPQSKETYMEFMQNFINKNSSSMRSFLKLIS 2189
C S+ E + W+ +++ I PN +++ R ++ L++W+ EAK L KKRY+CE++LD+ LYGRT++K TD +FWGE F+F + IN IT+ +++ D KKK ++ + V +++P D+T PCE+WY + L ++ K E L P +RIK R++ +ILP Y + +L + + E+LE + VK+KED + L++++ ++ FL D+V +++ + D L RGNS+A+K+ME +LK+ GE+YL L INE+I E DCEVDP + + S S + Q L V W I+ + P +L+ F RE+L + R M +IS+ +FLRF+CPAI+SP LF +++E P + R TL+AK++Q+LANF++F Q KE +MEF+ +F+ + ++ M+ FL++IS
Sbjct: 276 CGSRQERDLWIYSLRKSIAPNAEHTRRTDNSLKMWVYEAKNLPPKKRYFCELQLDKTLYGRTSVKLQTDLLFWGEHFDFPDIPEINVITVNVFREVDKKKKRDKYQFVGSVKIPVHDVTSRLPCEQWYPILSDKAGDSLGRTSGGGGSGSKDKEQL-------PTLRIKCRFQSTDILPINVYGNFLTYLKENYKRVCETLEPVIGVKAKEDIGQALVLLMHAQGLAGAFLTDVVALDLLRVGDQRLTFRGNSLATKSMEAFLKLTGEQYLQDTLSAPINELIQSERDCEVDPTKTSGSSAGS-LQRQQAALRGAVRGAWQCIFESHKHFPAQLRNCFATFRERLQQLGR-----QDMADNLISASIFLRFLCPAILSPSLFNITSELP-SARATRNLTLVAKTLQTLANFTRF-QGKENFMEFLNDFLEQEAARMQQFLEIIS 704
BLAST of Disabled 2-interacting protein vs. Ensembl Fly
Match: raskol (gene:FBgn0261570 transcript:FBtr0340629) HSP 1 Score: 316.62 bits (810), Expect = 5.405e-88 Identity = 162/444 (36.49%), Postives = 264/444 (59.46%), Query Frame = 3
Query: 861 CLSQPEMNEWLTKIKQRINPNYKNSTRHEDLLQIWIQEAKQLIQKKRYYCEIKLDEMLYGRTTIKTVTDTVFWGEEFEFRGLQNINKITICLYKMTDNKKKHERSELVAQIEVPCADLTDSSPCEKWYSPPFQYSNLRLSQSELTNSQKVKLDELLKNAVDIAPMIRIKGRYRPLEILPNKFYDSLSDFLVKQSIPLVESLESHLKVKSKEDFVKILLVILKSKDCHIDFLADLVFIEVSKAEDN-LILRGNSIASKAMECYLKMVGEKYLATILKDLINEVIFEEIDCEVDPLRLNNSKENSQIFENQNKLLRLVENVWSKIYHNAHLIPNELKLVFTKIREKLSETKRGSSYSSPMIYQVISSCLFLRFICPAIMSPFLFGLSNEYPDNVSINRTFTLIAKSIQSLANFSQFPQSKETYMEFMQNFINKNSSSMRSFLKLIS 2189
C S+ E + W+ +++ I PN +++ R ++ L++W+ EAK L KKRY+CE++LD+ LYGRT++K TD +FWGE F+F + IN IT+ +++ D KKK ++ + V +++P D+T PCE+WY + L ++ K E L P +RIK R++ +ILP Y + +L + + E+LE + VK+KED + L++++ ++ FL D+V +++ + D L RGNS+A+K+ME +LK+ GE+YL L INE+I E DCEVDP + + S S + Q L V W I+ + P +L+ F RE+L + R M +IS+ +FLRF+CPAI+SP LF +++E P + R TL+AK++Q+LANF++F Q KE +MEF+ +F+ + ++ M+ FL++IS
Sbjct: 276 CGSRQERDLWIYSLRKSIAPNAEHTRRTDNSLKMWVYEAKNLPPKKRYFCELQLDKTLYGRTSVKLQTDLLFWGEHFDFPDIPEINVITVNVFREVDKKKKRDKYQFVGSVKIPVHDVTSRLPCEQWYPILSDKAGDSLGRTSGGGGSGSKDKEQL-------PTLRIKCRFQSTDILPINVYGNFLTYLKENYKRVCETLEPVIGVKAKEDIGQALVLLMHAQGLAGAFLTDVVALDLLRVGDQRLTFRGNSLATKSMEAFLKLTGEQYLQDTLSAPINELIQSERDCEVDPTKTSGSSAGS-LQRQQAALRGAVRGAWQCIFESHKHFPAQLRNCFATFRERLQQLGR-----QDMADNLISASIFLRFLCPAILSPSLFNITSELP-SARATRNLTLVAKTLQTLANFTRF-QGKENFMEFLNDFLEQEAARMQQFLEIIS 704
BLAST of Disabled 2-interacting protein vs. Ensembl Fly
Match: raskol (gene:FBgn0261570 transcript:FBtr0340631) HSP 1 Score: 315.464 bits (807), Expect = 1.042e-87 Identity = 162/444 (36.49%), Postives = 264/444 (59.46%), Query Frame = 3
Query: 861 CLSQPEMNEWLTKIKQRINPNYKNSTRHEDLLQIWIQEAKQLIQKKRYYCEIKLDEMLYGRTTIKTVTDTVFWGEEFEFRGLQNINKITICLYKMTDNKKKHERSELVAQIEVPCADLTDSSPCEKWYSPPFQYSNLRLSQSELTNSQKVKLDELLKNAVDIAPMIRIKGRYRPLEILPNKFYDSLSDFLVKQSIPLVESLESHLKVKSKEDFVKILLVILKSKDCHIDFLADLVFIEVSKAEDN-LILRGNSIASKAMECYLKMVGEKYLATILKDLINEVIFEEIDCEVDPLRLNNSKENSQIFENQNKLLRLVENVWSKIYHNAHLIPNELKLVFTKIREKLSETKRGSSYSSPMIYQVISSCLFLRFICPAIMSPFLFGLSNEYPDNVSINRTFTLIAKSIQSLANFSQFPQSKETYMEFMQNFINKNSSSMRSFLKLIS 2189
C S+ E + W+ +++ I PN +++ R ++ L++W+ EAK L KKRY+CE++LD+ LYGRT++K TD +FWGE F+F + IN IT+ +++ D KKK ++ + V +++P D+T PCE+WY + L ++ K E L P +RIK R++ +ILP Y + +L + + E+LE + VK+KED + L++++ ++ FL D+V +++ + D L RGNS+A+K+ME +LK+ GE+YL L INE+I E DCEVDP + + S S + Q L V W I+ + P +L+ F RE+L + R M +IS+ +FLRF+CPAI+SP LF +++E P + R TL+AK++Q+LANF++F Q KE +MEF+ +F+ + ++ M+ FL++IS
Sbjct: 249 CGSRQERDLWIYSLRKSIAPNAEHTRRTDNSLKMWVYEAKNLPPKKRYFCELQLDKTLYGRTSVKLQTDLLFWGEHFDFPDIPEINVITVNVFREVDKKKKRDKYQFVGSVKIPVHDVTSRLPCEQWYPILSDKAGDSLGRTSGGGGSGSKDKEQL-------PTLRIKCRFQSTDILPINVYGNFLTYLKENYKRVCETLEPVIGVKAKEDIGQALVLLMHAQGLAGAFLTDVVALDLLRVGDQRLTFRGNSLATKSMEAFLKLTGEQYLQDTLSAPINELIQSERDCEVDPTKTSGSSAGS-LQRQQAALRGAVRGAWQCIFESHKHFPAQLRNCFATFRERLQQLGR-----QDMADNLISASIFLRFLCPAILSPSLFNITSELP-SARATRNLTLVAKTLQTLANFTRF-QGKENFMEFLNDFLEQEAARMQQFLEIIS 677
BLAST of Disabled 2-interacting protein vs. Ensembl Fly
Match: raskol (gene:FBgn0261570 transcript:FBtr0340630) HSP 1 Score: 315.464 bits (807), Expect = 1.169e-87 Identity = 162/444 (36.49%), Postives = 264/444 (59.46%), Query Frame = 3
Query: 861 CLSQPEMNEWLTKIKQRINPNYKNSTRHEDLLQIWIQEAKQLIQKKRYYCEIKLDEMLYGRTTIKTVTDTVFWGEEFEFRGLQNINKITICLYKMTDNKKKHERSELVAQIEVPCADLTDSSPCEKWYSPPFQYSNLRLSQSELTNSQKVKLDELLKNAVDIAPMIRIKGRYRPLEILPNKFYDSLSDFLVKQSIPLVESLESHLKVKSKEDFVKILLVILKSKDCHIDFLADLVFIEVSKAEDN-LILRGNSIASKAMECYLKMVGEKYLATILKDLINEVIFEEIDCEVDPLRLNNSKENSQIFENQNKLLRLVENVWSKIYHNAHLIPNELKLVFTKIREKLSETKRGSSYSSPMIYQVISSCLFLRFICPAIMSPFLFGLSNEYPDNVSINRTFTLIAKSIQSLANFSQFPQSKETYMEFMQNFINKNSSSMRSFLKLIS 2189
C S+ E + W+ +++ I PN +++ R ++ L++W+ EAK L KKRY+CE++LD+ LYGRT++K TD +FWGE F+F + IN IT+ +++ D KKK ++ + V +++P D+T PCE+WY + L ++ K E L P +RIK R++ +ILP Y + +L + + E+LE + VK+KED + L++++ ++ FL D+V +++ + D L RGNS+A+K+ME +LK+ GE+YL L INE+I E DCEVDP + + S S + Q L V W I+ + P +L+ F RE+L + R M +IS+ +FLRF+CPAI+SP LF +++E P + R TL+AK++Q+LANF++F Q KE +MEF+ +F+ + ++ M+ FL++IS
Sbjct: 258 CGSRQERDLWIYSLRKSIAPNAEHTRRTDNSLKMWVYEAKNLPPKKRYFCELQLDKTLYGRTSVKLQTDLLFWGEHFDFPDIPEINVITVNVFREVDKKKKRDKYQFVGSVKIPVHDVTSRLPCEQWYPILSDKAGDSLGRTSGGGGSGSKDKEQL-------PTLRIKCRFQSTDILPINVYGNFLTYLKENYKRVCETLEPVIGVKAKEDIGQALVLLMHAQGLAGAFLTDVVALDLLRVGDQRLTFRGNSLATKSMEAFLKLTGEQYLQDTLSAPINELIQSERDCEVDPTKTSGSSAGS-LQRQQAALRGAVRGAWQCIFESHKHFPAQLRNCFATFRERLQQLGR-----QDMADNLISASIFLRFLCPAILSPSLFNITSELP-SARATRNLTLVAKTLQTLANFTRF-QGKENFMEFLNDFLEQEAARMQQFLEIIS 686
BLAST of Disabled 2-interacting protein vs. Ensembl Fly
Match: raskol (gene:FBgn0261570 transcript:FBtr0302837) HSP 1 Score: 315.464 bits (807), Expect = 1.212e-87 Identity = 162/444 (36.49%), Postives = 264/444 (59.46%), Query Frame = 3
Query: 861 CLSQPEMNEWLTKIKQRINPNYKNSTRHEDLLQIWIQEAKQLIQKKRYYCEIKLDEMLYGRTTIKTVTDTVFWGEEFEFRGLQNINKITICLYKMTDNKKKHERSELVAQIEVPCADLTDSSPCEKWYSPPFQYSNLRLSQSELTNSQKVKLDELLKNAVDIAPMIRIKGRYRPLEILPNKFYDSLSDFLVKQSIPLVESLESHLKVKSKEDFVKILLVILKSKDCHIDFLADLVFIEVSKAEDN-LILRGNSIASKAMECYLKMVGEKYLATILKDLINEVIFEEIDCEVDPLRLNNSKENSQIFENQNKLLRLVENVWSKIYHNAHLIPNELKLVFTKIREKLSETKRGSSYSSPMIYQVISSCLFLRFICPAIMSPFLFGLSNEYPDNVSINRTFTLIAKSIQSLANFSQFPQSKETYMEFMQNFINKNSSSMRSFLKLIS 2189
C S+ E + W+ +++ I PN +++ R ++ L++W+ EAK L KKRY+CE++LD+ LYGRT++K TD +FWGE F+F + IN IT+ +++ D KKK ++ + V +++P D+T PCE+WY + L ++ K E L P +RIK R++ +ILP Y + +L + + E+LE + VK+KED + L++++ ++ FL D+V +++ + D L RGNS+A+K+ME +LK+ GE+YL L INE+I E DCEVDP + + S S + Q L V W I+ + P +L+ F RE+L + R M +IS+ +FLRF+CPAI+SP LF +++E P + R TL+AK++Q+LANF++F Q KE +MEF+ +F+ + ++ M+ FL++IS
Sbjct: 282 CGSRQERDLWIYSLRKSIAPNAEHTRRTDNSLKMWVYEAKNLPPKKRYFCELQLDKTLYGRTSVKLQTDLLFWGEHFDFPDIPEINVITVNVFREVDKKKKRDKYQFVGSVKIPVHDVTSRLPCEQWYPILSDKAGDSLGRTSGGGGSGSKDKEQL-------PTLRIKCRFQSTDILPINVYGNFLTYLKENYKRVCETLEPVIGVKAKEDIGQALVLLMHAQGLAGAFLTDVVALDLLRVGDQRLTFRGNSLATKSMEAFLKLTGEQYLQDTLSAPINELIQSERDCEVDPTKTSGSSAGS-LQRQQAALRGAVRGAWQCIFESHKHFPAQLRNCFATFRERLQQLGR-----QDMADNLISASIFLRFLCPAILSPSLFNITSELP-SARATRNLTLVAKTLQTLANFTRF-QGKENFMEFLNDFLEQEAARMQQFLEIIS 710
BLAST of Disabled 2-interacting protein vs. Ensembl Zebrafish
Match: syngap1b (synaptic Ras GTPase activating protein 1b [Source:ZFIN;Acc:ZDB-GENE-100921-2]) HSP 1 Score: 301.982 bits (772), Expect = 5.892e-84 Identity = 205/592 (34.63%), Postives = 297/592 (50.17%), Query Frame = 3
Query: 627 VLDNQSLVQTLHSSLTNHQNFCFQIIKKEQTLDLAKPFCSVTVGXXXXXXXXXXXXXXXXXXXXXXXXXXTDSVINIRCLSQPEMNEWLTKIKQRINPNYKNSTRHEDLLQIWIQEAKQLIQKKRYYCEIKLDEMLYGRTTIKTVTDTVFWGEEFEFRGLQNINKITICLYKMTDNKKKHERSELVAQIEVPCADLTDSSPCEKWYSPPFQYSNLRLSQSELTNSQKVKLDELLKNAVDIAPMIRIKGRYRPLEILPNKFYDSLSDFLVKQSIPLVESLESHLKVKSKEDFVKILLVILKSKDCHIDFLADLVFIEVSKAED--NLILRGNSIASKAMECYLKMVGEKYLATILKDLINEVIFEEIDCEVDPLRLNNSKENSQIFENQNKLLRLVENVWSKIYHNAHLIPNELKLVFTKIREKLSETKRGSSYSSPMIYQVISSCLFLRFICPAIMSPFLFGLSNEYPDNVSINRTFTLIAKSIQSLANFSQFPQSKETYMEFMQNFINKNSSSMRSFLKLIS-LNKSNGAKSMESQDVLYLLLETDKINYSPTKDDRYIDIGYHLA-------ELMFQLN----IHLKDIP 2360
LD ++++ +HSS+ Q +CF++I T A C S E ++W+ +++ + PN NS R +++L++WI EA++L KKRYYCE+ LD+MLY RTT K TDTVFWGE FEF L + + + LYK TD K++ E+S + + +P + +T E+WY P Q S L++ K+ I +R+K R++ + ILP + Y ++++ L LE L VKSKE+ L+ IL+S DFL+D+ EV + D +LI R N++A+KA+E YLK++G KYL +L D I + E +CEVDP+R S + E+Q L E KI ++ P ELK VF R + +E R + ++IS LFLRF+CPAIMSP LF L+ EYPD +RT TLIAK +Q+LANFS+F SKE YM FM F+ SM+ FL IS L+ + A + E YID+G L+ E+M QL+ I L +P
Sbjct: 85 TLDEDAIIKPVHSSILG-QEYCFEVITASGTKCFA-------------------------------------------CRSAAERDKWIENLQRAVKPNKDNSRRVDNVLKLWIIEARELPPKKRYYCELCLDDMLYARTTSKPRTDTVFWGEHFEFNNLPAVRNLRLHLYKETDKKRRKEKSTYLGLVSIPISSITGRQFVEQWY-PVIQPSV--LAKGGGVGGGKI-----------INASLRLKSRFQTMSILPMELYKEFAEYVTNNYRTLCAVLEPLLSVKSKEEVACALVHILQSTGKAKDFLSDMAMCEVDRFIDREHLIFRENTLATKAIEEYLKLIGHKYLKDVLGDFIRALYESEENCEVDPMR----TPPSILPEHQANLRMCCELALCKIINSYCAFPRELKEVFASWRVRCAERGRED-----IADRLISGSLFLRFLCPAIMSPSLFNLTQEYPDE-QTSRTLTLIAKVVQNLANFSKF-GSKEEYMCFMNEFLEMEWGSMQQFLYEISNLDSVSNAGAFEG----------------------YIDLGRELSILHSLLWEVMAQLSKDAIIKLGPLP 585
BLAST of Disabled 2-interacting protein vs. Ensembl Zebrafish
Match: syngap1b (synaptic Ras GTPase activating protein 1b [Source:ZFIN;Acc:ZDB-GENE-100921-2]) HSP 1 Score: 301.597 bits (771), Expect = 3.825e-83 Identity = 202/581 (34.77%), Postives = 293/581 (50.43%), Query Frame = 3
Query: 627 VLDNQSLVQTLHSSLTNHQNFCFQIIKKEQTLDLAKPFCSVTVGXXXXXXXXXXXXXXXXXXXXXXXXXXTDSVINIRCLSQPEMNEWLTKIKQRINPNYKNSTRHEDLLQIWIQEAKQLIQKKRYYCEIKLDEMLYGRTTIKTVTDTVFWGEEFEFRGLQNINKITICLYKMTDNKKKHERSELVAQIEVPCADLTDSSPCEKWYSPPFQYSNLRLSQSELTNSQKVKLDELLKNAVDIAPMIRIKGRYRPLEILPNKFYDSLSDFLVKQSIPLVESLESHLKVKSKEDFVKILLVILKSKDCHIDFLADLVFIEVSKAED--NLILRGNSIASKAMECYLKMVGEKYLATILKDLINEVIFEEIDCEVDPLRLNNSKENSQIFENQNKLLRLVENVWSKIYHNAHLIPNELKLVFTKIREKLSETKRGSSYSSPMIYQVISSCLFLRFICPAIMSPFLFGLSNEYPDNVSINRTFTLIAKSIQSLANFSQFPQSKETYMEFMQNFINKNSSSMRSFLKLIS-LNKSNGAKSMESQDVLYLLLETDKINYSPTKDDRYIDIGYHLA-------ELMFQLN 2339
LD ++++ +HSS+ Q +CF++I T A C S E ++W+ +++ + PN NS R +++L++WI EA++L KKRYYCE+ LD+MLY RTT K TDTVFWGE FEF L + + + LYK TD K++ E+S + + +P + +T E+WY P Q S L++ K+ I +R+K R++ + ILP + Y ++++ L LE L VKSKE+ L+ IL+S DFL+D+ EV + D +LI R N++A+KA+E YLK++G KYL +L D I + E +CEVDP+R S + E+Q L E KI ++ P ELK VF R + +E R + ++IS LFLRF+CPAIMSP LF L+ EYPD +RT TLIAK +Q+LANFS+F SKE YM FM F+ SM+ FL IS L+ + A + E YID+G L+ E+M QL+
Sbjct: 284 TLDEDAIIKPVHSSILG-QEYCFEVITASGTKCFA-------------------------------------------CRSAAERDKWIENLQRAVKPNKDNSRRVDNVLKLWIIEARELPPKKRYYCELCLDDMLYARTTSKPRTDTVFWGEHFEFNNLPAVRNLRLHLYKETDKKRRKEKSTYLGLVSIPISSITGRQFVEQWY-PVIQPSV--LAKGGGVGGGKI-----------INASLRLKSRFQTMSILPMELYKEFAEYVTNNYRTLCAVLEPLLSVKSKEEVACALVHILQSTGKAKDFLSDMAMCEVDRFIDREHLIFRENTLATKAIEEYLKLIGHKYLKDVLGDFIRALYESEENCEVDPMR----TPPSILPEHQANLRMCCELALCKIINSYCAFPRELKEVFASWRVRCAERGRED-----IADRLISGSLFLRFLCPAIMSPSLFNLTQEYPDE-QTSRTLTLIAKVVQNLANFSKF-GSKEEYMCFMNEFLEMEWGSMQQFLYEISNLDSVSNAGAFEG----------------------YIDLGRELSILHSLLWEVMAQLS 773
BLAST of Disabled 2-interacting protein vs. Ensembl Zebrafish
Match: dab2ipa (DAB2 interacting protein a [Source:ZFIN;Acc:ZDB-GENE-081104-516]) HSP 1 Score: 296.59 bits (758), Expect = 1.283e-82 Identity = 180/446 (40.36%), Postives = 257/446 (57.62%), Query Frame = 3
Query: 861 CLSQPEMNEWLTKIKQRINPNYKNSTRHEDLLQIWIQEAKQLIQKKRYYCEIKLDEMLYGRTTIKTVTDTVFWGEEFEFRGLQNINKITICLYKMTDNKKKHERSELVAQIEVPCADLTDSSPCEKWYSPPFQYSNLRLSQSELTNSQKVKLDELLKNAVDIAPMIRIKGRYRPLEILPNKFYDSLSDFLVKQSIPLVESLESHLKVKSKEDFVKILLVILKSKDCHIDFLADLVFIEVSKAEDN--LILRGNSIASKAMECYLKMVGEKYLATILKDLINEVIFEEIDCEVDPLRLNNSKENSQIFENQNKLLRLVENVWSKIYHNAHLIPNELKLVFTKIREKLSETKRGSSYSSPMIYQ-VISSCLFLRFICPAIMSPFLFGLSNEYPDNVSINRTFTLIAKSIQSLANFSQFPQSKETYMEFMQNFINKNSSSMRSFLKLIS 2189
C S E ++W+ +++ ++PN N+ R E++L+ WI EAK L KK+Y+CE+ LD+ LY RTT K TD VFWGE FEF L ++ IT+ LYK TD KKK +++ V + +P A +T EKWYS N K K PM+R+K RY+ + ILP + Y ++++ + + LE L VK+KE+ L+ IL+S DFL DL+ EV + DN LI R N++A+KA+E YLK+VG+KYL L + I + + +CEVDP + + +S + E+Q+ L E + KI ++ + P ELK VF R++ S R P I + +IS+ LFLRF+CPAIMSP LF L EYPD+ + RT TLIAK Q+LANF++F SKE YM FM F+ ++M+ FL IS
Sbjct: 128 CRSAAERDKWMENLRRAVHPNKDNTRRVENMLKCWIIEAKDLPAKKKYFCELCLDDTLYARTTCKLKTDNVFWGEHFEFNNLPSVKSITVHLYKETDKKKKKDKNNYVGLVNIPIATVTGRQFVEKWYS------------VSTPNPNKGK---------SPGPMVRMKSRYQSMSILPMELYKEFAEYITNNYMLMCSVLEPALSVKNKEEMACALVHILQSTGKAKDFLTDLMMSEVDRCGDNEHLIFRENTLATKAIEEYLKLVGQKYLQDALGEFIKALYESDENCEVDPSKCS----SSDLHEHQSNLKMCCELAFCKIINSYCVFPRELKEVFASWRQECSSRGR------PDISERLISASLFLRFLCPAIMSPSLFSLMQEYPDDRTA-RTLTLIAKVTQNLANFTKF-GSKEEYMSFMNQFLEHEWTNMQRFLLEIS 540
BLAST of Disabled 2-interacting protein vs. Ensembl Zebrafish
Match: dab2ipa (DAB2 interacting protein a [Source:ZFIN;Acc:ZDB-GENE-081104-516]) HSP 1 Score: 296.204 bits (757), Expect = 1.671e-82 Identity = 180/446 (40.36%), Postives = 257/446 (57.62%), Query Frame = 3
Query: 861 CLSQPEMNEWLTKIKQRINPNYKNSTRHEDLLQIWIQEAKQLIQKKRYYCEIKLDEMLYGRTTIKTVTDTVFWGEEFEFRGLQNINKITICLYKMTDNKKKHERSELVAQIEVPCADLTDSSPCEKWYSPPFQYSNLRLSQSELTNSQKVKLDELLKNAVDIAPMIRIKGRYRPLEILPNKFYDSLSDFLVKQSIPLVESLESHLKVKSKEDFVKILLVILKSKDCHIDFLADLVFIEVSKAEDN--LILRGNSIASKAMECYLKMVGEKYLATILKDLINEVIFEEIDCEVDPLRLNNSKENSQIFENQNKLLRLVENVWSKIYHNAHLIPNELKLVFTKIREKLSETKRGSSYSSPMIYQ-VISSCLFLRFICPAIMSPFLFGLSNEYPDNVSINRTFTLIAKSIQSLANFSQFPQSKETYMEFMQNFINKNSSSMRSFLKLIS 2189
C S E ++W+ +++ ++PN N+ R E++L+ WI EAK L KK+Y+CE+ LD+ LY RTT K TD VFWGE FEF L ++ IT+ LYK TD KKK +++ V + +P A +T EKWYS N K K PM+R+K RY+ + ILP + Y ++++ + + LE L VK+KE+ L+ IL+S DFL DL+ EV + DN LI R N++A+KA+E YLK+VG+KYL L + I + + +CEVDP + + +S + E+Q+ L E + KI ++ + P ELK VF R++ S R P I + +IS+ LFLRF+CPAIMSP LF L EYPD+ + RT TLIAK Q+LANF++F SKE YM FM F+ ++M+ FL IS
Sbjct: 140 CRSAAERDKWMENLRRAVHPNKDNTRRVENMLKCWIIEAKDLPAKKKYFCELCLDDTLYARTTCKLKTDNVFWGEHFEFNNLPSVKSITVHLYKETDKKKKKDKNNYVGLVNIPIATVTGRQFVEKWYS------------VSTPNPNKGK---------SPGPMVRMKSRYQSMSILPMELYKEFAEYITNNYMLMCSVLEPALSVKNKEEMACALVHILQSTGKAKDFLTDLMMSEVDRCGDNEHLIFRENTLATKAIEEYLKLVGQKYLQDALGEFIKALYESDENCEVDPSKCS----SSDLHEHQSNLKMCCELAFCKIINSYCVFPRELKEVFASWRQECSSRGR------PDISERLISASLFLRFLCPAIMSPSLFSLMQEYPDDRTA-RTLTLIAKVTQNLANFTKF-GSKEEYMSFMNQFLEHEWTNMQRFLLEIS 552
BLAST of Disabled 2-interacting protein vs. Ensembl Zebrafish
Match: dab2ipb (DAB2 interacting protein b [Source:ZFIN;Acc:ZDB-GENE-030131-2449]) HSP 1 Score: 288.5 bits (737), Expect = 4.774e-80 Identity = 176/446 (39.46%), Postives = 256/446 (57.40%), Query Frame = 3
Query: 861 CLSQPEMNEWLTKIKQRINPNYKNSTRHEDLLQIWIQEAKQLIQKKRYYCEIKLDEMLYGRTTIKTVTDTVFWGEEFEFRGLQNINKITICLYKMTDNKKKHERSELVAQIEVPCADLTDSSPCEKWYSPPFQYSNLRLSQSELTNSQKVKLDELLKNAVDIAPMIRIKGRYRPLEILPNKFYDSLSDFLVKQSIPLVESLESHLKVKSKEDFVKILLVILKSKDCHIDFLADLVFIEVSKAEDN--LILRGNSIASKAMECYLKMVGEKYLATILKDLINEVIFEEIDCEVDPLRLNNSKENSQIFENQNKLLRLVENVWSKIYHNAHLIPNELKLVFTKIREKLSETKRGSSYSSPMIYQ-VISSCLFLRFICPAIMSPFLFGLSNEYPDNVSINRTFTLIAKSIQSLANFSQFPQSKETYMEFMQNFINKNSSSMRSFLKLIS 2189
C S E ++W+ +++ I+PN NS R E++L++WI EAK L KK+Y+CE+ LD+ LY RTT K TD VFWGE FEF L + IT+ +Y+ +D KKK +++ V + +P +T EKWY +SQ N K K PM+RIK RY+ + ILP + Y +++ + L LE + VK+KE+ L+ IL+S DFL DL+ EV + +N LI R N++ +KA+E YLK+VG+KYL L + I + + +CEVDP + + +S + E+Q+ L E + KI + + P ELK VF R++ R P I + +IS+ LFLRF+CPAIMSP LF L+ EYPD+ + RT TLIAK Q+LANF++F +KE YM FM F+ + ++M+ FL IS
Sbjct: 112 CRSAAERDKWMENLRRAIHPNKDNSRRVENMLRLWIIEAKDLPAKKKYFCELCLDDSLYARTTCKMKTDNVFWGEHFEFNNLPAVQSITVHVYRDSDKKKKKDKNNYVGLVSIPVVTVTSRQLVEKWYP---------VSQ---PNPGKGKA---------AGPMVRIKARYQSMNILPMELYKEFAEYTTNNYMLLCSVLEPVISVKNKEEMACALVHILQSTGKAKDFLTDLMMSEVDRCGENEHLIFRENTLGTKAIEEYLKLVGQKYLQDALGEFIKALYESDENCEVDPSKCS----SSDLPEHQSNLRMCCELAFCKIIESYRVFPRELKEVFASWRQECGNRGR------PDISERLISASLFLRFLCPAIMSPSLFNLTQEYPDDRTA-RTLTLIAKVTQNLANFTKF-GNKEEYMSFMNQFLEQEWTNMQRFLLEIS 524
BLAST of Disabled 2-interacting protein vs. Ensembl Xenopus
Match: SYNGAP1 (synaptic Ras GTPase activating protein 1 [Source:NCBI gene;Acc:100038210]) HSP 1 Score: 298.901 bits (764), Expect = 1.586e-83 Identity = 198/567 (34.92%), Postives = 289/567 (50.97%), Query Frame = 3
Query: 630 LDNQSLVQTLHSSLTNHQNFCFQIIKKEQTLDLAKPFCSVTVGXXXXXXXXXXXXXXXXXXXXXXXXXXTDSVINIRCLSQPEMNEWLTKIKQRINPNYKNSTRHEDLLQIWIQEAKQLIQKKRYYCEIKLDEMLYGRTTIKTVTDTVFWGEEFEFRGLQNINKITICLYKMTDNKKKHERSELVAQIEVPCADLTDSSPCEKWYSPPFQYSNLRLSQSELTNSQKVKLDELLKNAVDIAPMIRIKGRYRPLEILPNKFYDSLSDFLVKQSIPLVESLESHLKVKSKEDFVKILLVILKSKDCHIDFLADLVFIEVSKAED--NLILRGNSIASKAMECYLKMVGEKYLATILKDLINEVIFEEIDCEVDPLRLNNSKENSQIFENQNKLLRLVENVWSKIYHNAHLIPNELKLVFTKIREKLSETKRGSSYSSPMIYQVISSCLFLRFICPAIMSPFLFGLSNEYPDNVSINRTFTLIAKSIQSLANFSQFPQSKETYMEFMQNFINKNSSSMRSFLKLISLNKSNGAKSMESQDVLYLLLETDKINYSPTKDDRYIDIGYHLAEL 2324
LD S+V+ +HSS+ Q FCF++ T A C S E ++W+ +++ + PN NS R +++L++WI EA+ L KKRYYCE+ LD++LY RTT K DTVFWGE FEF L + + + LYK TD K++ E+S V + VP A ++ E+WY P Q ++ + S P IR+K RY+ + ILP + Y ++++ L LE L VKSKE+ L+ IL+S DFL+D+ EV + D +LILR N++A+KA+E YLK++G++YL + + I + E DCEVDP+R S + ++Q L E K++++ + P ELK VF R + +E R + ++IS+ LFLRF+CPAIMSP LF L EYPD +RT TLIAK IQ+LANF+ SKE YM FM F+ ++M++FL IS + D L T+ IN+ + YID+G L+ L
Sbjct: 103 LDEDSVVKPVHSSILG-QEFCFEVTTSSGTKCFA-------------------------------------------CRSAAERDKWIENLQRAVKPNKDNSRRVDNVLKLWIIEARDLPPKKRYYCELCLDDILYARTTSKPRNDTVFWGEHFEFNNLPAVRNLRLHLYKDTDKKRRKEKSNYVGMVNVPIASISGRHFVEQWY-PVSQPTSYKGKSS--------------------CPSIRLKSRYQTMSILPMELYKEFAEYVTNNYRMLCAVLEPVLSVKSKEEVACALVHILQSTGKAKDFLSDMAMTEVDRFLDREHLILRENTLATKAIEEYLKLIGQRYLKEAIGEFIRALYESEEDCEVDPMRC----PPSALPDHQANLRMCCELALCKVFNSHCVFPRELKEVFASWRMRCAERGRED-----IADRLISASLFLRFLCPAIMSPSLFSLMQEYPDE-QTSRTLTLIAKVIQNLANFNYKFSSKEEYMSFMNEFLETELANMQNFLYEIS-----------NLDSL-----TNSINF-----EGYIDLGRELSTL 573
BLAST of Disabled 2-interacting protein vs. Ensembl Xenopus
Match: SYNGAP1 (synaptic Ras GTPase activating protein 1 [Source:NCBI gene;Acc:100038210]) HSP 1 Score: 299.286 bits (765), Expect = 1.909e-83 Identity = 198/567 (34.92%), Postives = 289/567 (50.97%), Query Frame = 3
Query: 630 LDNQSLVQTLHSSLTNHQNFCFQIIKKEQTLDLAKPFCSVTVGXXXXXXXXXXXXXXXXXXXXXXXXXXTDSVINIRCLSQPEMNEWLTKIKQRINPNYKNSTRHEDLLQIWIQEAKQLIQKKRYYCEIKLDEMLYGRTTIKTVTDTVFWGEEFEFRGLQNINKITICLYKMTDNKKKHERSELVAQIEVPCADLTDSSPCEKWYSPPFQYSNLRLSQSELTNSQKVKLDELLKNAVDIAPMIRIKGRYRPLEILPNKFYDSLSDFLVKQSIPLVESLESHLKVKSKEDFVKILLVILKSKDCHIDFLADLVFIEVSKAED--NLILRGNSIASKAMECYLKMVGEKYLATILKDLINEVIFEEIDCEVDPLRLNNSKENSQIFENQNKLLRLVENVWSKIYHNAHLIPNELKLVFTKIREKLSETKRGSSYSSPMIYQVISSCLFLRFICPAIMSPFLFGLSNEYPDNVSINRTFTLIAKSIQSLANFSQFPQSKETYMEFMQNFINKNSSSMRSFLKLISLNKSNGAKSMESQDVLYLLLETDKINYSPTKDDRYIDIGYHLAEL 2324
LD S+V+ +HSS+ Q FCF++ T A C S E ++W+ +++ + PN NS R +++L++WI EA+ L KKRYYCE+ LD++LY RTT K DTVFWGE FEF L + + + LYK TD K++ E+S V + VP A ++ E+WY P Q ++ + S P IR+K RY+ + ILP + Y ++++ L LE L VKSKE+ L+ IL+S DFL+D+ EV + D +LILR N++A+KA+E YLK++G++YL + + I + E DCEVDP+R S + ++Q L E K++++ + P ELK VF R + +E R + ++IS+ LFLRF+CPAIMSP LF L EYPD +RT TLIAK IQ+LANF+ SKE YM FM F+ ++M++FL IS + D L T+ IN+ + YID+G L+ L
Sbjct: 118 LDEDSVVKPVHSSILG-QEFCFEVTTSSGTKCFA-------------------------------------------CRSAAERDKWIENLQRAVKPNKDNSRRVDNVLKLWIIEARDLPPKKRYYCELCLDDILYARTTSKPRNDTVFWGEHFEFNNLPAVRNLRLHLYKDTDKKRRKEKSNYVGMVNVPIASISGRHFVEQWY-PVSQPTSYKGKSS--------------------CPSIRLKSRYQTMSILPMELYKEFAEYVTNNYRMLCAVLEPVLSVKSKEEVACALVHILQSTGKAKDFLSDMAMTEVDRFLDREHLILRENTLATKAIEEYLKLIGQRYLKEAIGEFIRALYESEEDCEVDPMRC----PPSALPDHQANLRMCCELALCKVFNSHCVFPRELKEVFASWRMRCAERGRED-----IADRLISASLFLRFLCPAIMSPSLFSLMQEYPDE-QTSRTLTLIAKVIQNLANFNYKFSSKEEYMSFMNEFLETELANMQNFLYEIS-----------NLDSL-----TNSINF-----EGYIDLGRELSTL 588
BLAST of Disabled 2-interacting protein vs. Ensembl Xenopus
Match: SYNGAP1 (synaptic Ras GTPase activating protein 1 [Source:NCBI gene;Acc:100038210]) HSP 1 Score: 298.901 bits (764), Expect = 2.943e-83 Identity = 198/567 (34.92%), Postives = 289/567 (50.97%), Query Frame = 3
Query: 630 LDNQSLVQTLHSSLTNHQNFCFQIIKKEQTLDLAKPFCSVTVGXXXXXXXXXXXXXXXXXXXXXXXXXXTDSVINIRCLSQPEMNEWLTKIKQRINPNYKNSTRHEDLLQIWIQEAKQLIQKKRYYCEIKLDEMLYGRTTIKTVTDTVFWGEEFEFRGLQNINKITICLYKMTDNKKKHERSELVAQIEVPCADLTDSSPCEKWYSPPFQYSNLRLSQSELTNSQKVKLDELLKNAVDIAPMIRIKGRYRPLEILPNKFYDSLSDFLVKQSIPLVESLESHLKVKSKEDFVKILLVILKSKDCHIDFLADLVFIEVSKAED--NLILRGNSIASKAMECYLKMVGEKYLATILKDLINEVIFEEIDCEVDPLRLNNSKENSQIFENQNKLLRLVENVWSKIYHNAHLIPNELKLVFTKIREKLSETKRGSSYSSPMIYQVISSCLFLRFICPAIMSPFLFGLSNEYPDNVSINRTFTLIAKSIQSLANFSQFPQSKETYMEFMQNFINKNSSSMRSFLKLISLNKSNGAKSMESQDVLYLLLETDKINYSPTKDDRYIDIGYHLAEL 2324
LD S+V+ +HSS+ Q FCF++ T A C S E ++W+ +++ + PN NS R +++L++WI EA+ L KKRYYCE+ LD++LY RTT K DTVFWGE FEF L + + + LYK TD K++ E+S V + VP A ++ E+WY P Q ++ + S P IR+K RY+ + ILP + Y ++++ L LE L VKSKE+ L+ IL+S DFL+D+ EV + D +LILR N++A+KA+E YLK++G++YL + + I + E DCEVDP+R S + ++Q L E K++++ + P ELK VF R + +E R + ++IS+ LFLRF+CPAIMSP LF L EYPD +RT TLIAK IQ+LANF+ SKE YM FM F+ ++M++FL IS + D L T+ IN+ + YID+G L+ L
Sbjct: 95 LDEDSVVKPVHSSILG-QEFCFEVTTSSGTKCFA-------------------------------------------CRSAAERDKWIENLQRAVKPNKDNSRRVDNVLKLWIIEARDLPPKKRYYCELCLDDILYARTTSKPRNDTVFWGEHFEFNNLPAVRNLRLHLYKDTDKKRRKEKSNYVGMVNVPIASISGRHFVEQWY-PVSQPTSYKGKSS--------------------CPSIRLKSRYQTMSILPMELYKEFAEYVTNNYRMLCAVLEPVLSVKSKEEVACALVHILQSTGKAKDFLSDMAMTEVDRFLDREHLILRENTLATKAIEEYLKLIGQRYLKEAIGEFIRALYESEEDCEVDPMRC----PPSALPDHQANLRMCCELALCKVFNSHCVFPRELKEVFASWRMRCAERGRED-----IADRLISASLFLRFLCPAIMSPSLFSLMQEYPDE-QTSRTLTLIAKVIQNLANFNYKFSSKEEYMSFMNEFLETELANMQNFLYEIS-----------NLDSL-----TNSINF-----EGYIDLGRELSTL 565
BLAST of Disabled 2-interacting protein vs. Ensembl Xenopus
Match: SYNGAP1 (synaptic Ras GTPase activating protein 1 [Source:NCBI gene;Acc:100038210]) HSP 1 Score: 298.13 bits (762), Expect = 3.790e-83 Identity = 198/567 (34.92%), Postives = 289/567 (50.97%), Query Frame = 3
Query: 630 LDNQSLVQTLHSSLTNHQNFCFQIIKKEQTLDLAKPFCSVTVGXXXXXXXXXXXXXXXXXXXXXXXXXXTDSVINIRCLSQPEMNEWLTKIKQRINPNYKNSTRHEDLLQIWIQEAKQLIQKKRYYCEIKLDEMLYGRTTIKTVTDTVFWGEEFEFRGLQNINKITICLYKMTDNKKKHERSELVAQIEVPCADLTDSSPCEKWYSPPFQYSNLRLSQSELTNSQKVKLDELLKNAVDIAPMIRIKGRYRPLEILPNKFYDSLSDFLVKQSIPLVESLESHLKVKSKEDFVKILLVILKSKDCHIDFLADLVFIEVSKAED--NLILRGNSIASKAMECYLKMVGEKYLATILKDLINEVIFEEIDCEVDPLRLNNSKENSQIFENQNKLLRLVENVWSKIYHNAHLIPNELKLVFTKIREKLSETKRGSSYSSPMIYQVISSCLFLRFICPAIMSPFLFGLSNEYPDNVSINRTFTLIAKSIQSLANFSQFPQSKETYMEFMQNFINKNSSSMRSFLKLISLNKSNGAKSMESQDVLYLLLETDKINYSPTKDDRYIDIGYHLAEL 2324
LD S+V+ +HSS+ Q FCF++ T A C S E ++W+ +++ + PN NS R +++L++WI EA+ L KKRYYCE+ LD++LY RTT K DTVFWGE FEF L + + + LYK TD K++ E+S V + VP A ++ E+WY P Q ++ + S P IR+K RY+ + ILP + Y ++++ L LE L VKSKE+ L+ IL+S DFL+D+ EV + D +LILR N++A+KA+E YLK++G++YL + + I + E DCEVDP+R S + ++Q L E K++++ + P ELK VF R + +E R + ++IS+ LFLRF+CPAIMSP LF L EYPD +RT TLIAK IQ+LANF+ SKE YM FM F+ ++M++FL IS + D L T+ IN+ + YID+G L+ L
Sbjct: 182 LDEDSVVKPVHSSILG-QEFCFEVTTSSGTKCFA-------------------------------------------CRSAAERDKWIENLQRAVKPNKDNSRRVDNVLKLWIIEARDLPPKKRYYCELCLDDILYARTTSKPRNDTVFWGEHFEFNNLPAVRNLRLHLYKDTDKKRRKEKSNYVGMVNVPIASISGRHFVEQWY-PVSQPTSYKGKSS--------------------CPSIRLKSRYQTMSILPMELYKEFAEYVTNNYRMLCAVLEPVLSVKSKEEVACALVHILQSTGKAKDFLSDMAMTEVDRFLDREHLILRENTLATKAIEEYLKLIGQRYLKEAIGEFIRALYESEEDCEVDPMRC----PPSALPDHQANLRMCCELALCKVFNSHCVFPRELKEVFASWRMRCAERGRED-----IADRLISASLFLRFLCPAIMSPSLFSLMQEYPDE-QTSRTLTLIAKVIQNLANFNYKFSSKEEYMSFMNEFLETELANMQNFLYEIS-----------NLDSL-----TNSINF-----EGYIDLGRELSTL 652
BLAST of Disabled 2-interacting protein vs. Ensembl Xenopus
Match: SYNGAP1 (synaptic Ras GTPase activating protein 1 [Source:NCBI gene;Acc:100038210]) HSP 1 Score: 298.901 bits (764), Expect = 4.770e-83 Identity = 198/567 (34.92%), Postives = 289/567 (50.97%), Query Frame = 3
Query: 630 LDNQSLVQTLHSSLTNHQNFCFQIIKKEQTLDLAKPFCSVTVGXXXXXXXXXXXXXXXXXXXXXXXXXXTDSVINIRCLSQPEMNEWLTKIKQRINPNYKNSTRHEDLLQIWIQEAKQLIQKKRYYCEIKLDEMLYGRTTIKTVTDTVFWGEEFEFRGLQNINKITICLYKMTDNKKKHERSELVAQIEVPCADLTDSSPCEKWYSPPFQYSNLRLSQSELTNSQKVKLDELLKNAVDIAPMIRIKGRYRPLEILPNKFYDSLSDFLVKQSIPLVESLESHLKVKSKEDFVKILLVILKSKDCHIDFLADLVFIEVSKAED--NLILRGNSIASKAMECYLKMVGEKYLATILKDLINEVIFEEIDCEVDPLRLNNSKENSQIFENQNKLLRLVENVWSKIYHNAHLIPNELKLVFTKIREKLSETKRGSSYSSPMIYQVISSCLFLRFICPAIMSPFLFGLSNEYPDNVSINRTFTLIAKSIQSLANFSQFPQSKETYMEFMQNFINKNSSSMRSFLKLISLNKSNGAKSMESQDVLYLLLETDKINYSPTKDDRYIDIGYHLAEL 2324
LD S+V+ +HSS+ Q FCF++ T A C S E ++W+ +++ + PN NS R +++L++WI EA+ L KKRYYCE+ LD++LY RTT K DTVFWGE FEF L + + + LYK TD K++ E+S V + VP A ++ E+WY P Q ++ + S P IR+K RY+ + ILP + Y ++++ L LE L VKSKE+ L+ IL+S DFL+D+ EV + D +LILR N++A+KA+E YLK++G++YL + + I + E DCEVDP+R S + ++Q L E K++++ + P ELK VF R + +E R + ++IS+ LFLRF+CPAIMSP LF L EYPD +RT TLIAK IQ+LANF+ SKE YM FM F+ ++M++FL IS + D L T+ IN+ + YID+G L+ L
Sbjct: 181 LDEDSVVKPVHSSILG-QEFCFEVTTSSGTKCFA-------------------------------------------CRSAAERDKWIENLQRAVKPNKDNSRRVDNVLKLWIIEARDLPPKKRYYCELCLDDILYARTTSKPRNDTVFWGEHFEFNNLPAVRNLRLHLYKDTDKKRRKEKSNYVGMVNVPIASISGRHFVEQWY-PVSQPTSYKGKSS--------------------CPSIRLKSRYQTMSILPMELYKEFAEYVTNNYRMLCAVLEPVLSVKSKEEVACALVHILQSTGKAKDFLSDMAMTEVDRFLDREHLILRENTLATKAIEEYLKLIGQRYLKEAIGEFIRALYESEEDCEVDPMRC----PPSALPDHQANLRMCCELALCKVFNSHCVFPRELKEVFASWRMRCAERGRED-----IADRLISASLFLRFLCPAIMSPSLFSLMQEYPDE-QTSRTLTLIAKVIQNLANFNYKFSSKEEYMSFMNEFLETELANMQNFLYEIS-----------NLDSL-----TNSINF-----EGYIDLGRELSTL 651
BLAST of Disabled 2-interacting protein vs. Ensembl Mouse
Match: Dab2ip (disabled 2 interacting protein [Source:MGI Symbol;Acc:MGI:1916851]) HSP 1 Score: 303.523 bits (776), Expect = 2.760e-85 Identity = 178/446 (39.91%), Postives = 252/446 (56.50%), Query Frame = 3
Query: 861 CLSQPEMNEWLTKIKQRINPNYKNSTRHEDLLQIWIQEAKQLIQKKRYYCEIKLDEMLYGRTTIKTVTDTVFWGEEFEFRGLQNINKITICLYKMTDNKKKHERSELVAQIEVPCADLTDSSPCEKWYSPPFQYSNLRLSQSELTNSQKVKLDELLKNAVDIAPMIRIKGRYRPLEILPNKFYDSLSDFLVKQSIPLVESLESHLKVKSKEDFVKILLVILKSKDCHIDFLADLVFIEVSKAEDN--LILRGNSIASKAMECYLKMVGEKYLATILKDLINEVIFEEIDCEVDPLRLNNSKENSQIFENQNKLLRLVENVWSKIYHNAHLIPNELKLVFTKIREKLSETKRGSSYSSPMIYQ-VISSCLFLRFICPAIMSPFLFGLSNEYPDNVSINRTFTLIAKSIQSLANFSQFPQSKETYMEFMQNFINKNSSSMRSFLKLIS 2189
C S E ++W+ +++ ++PN NS R E +L++W+ EAK L KK+Y CE+ LD++LY RTT K TD VFWGE FEF L + +T+ LY+ TD KKK ER+ + + +P A + EKWY P N K PMIRIK RY+ + ILP + Y ++ + + L +LE L K+KE+ L+ IL+S DFL DL+ EV + DN LI R N++A+KA+E YLK+VG+KYL L + I + + +CEVDP + + ++ + E+Q L E + KI ++ + P ELK VF R++ S R P I + +IS+ LFLRF+CPAIMSP LF L EYPD+ + RT TLIAK Q+LANF++F SKE YM FM F+ ++M+ FL IS
Sbjct: 60 CRSAAERDKWMENLRRAVHPNKDNSRRVEHILKLWVIEAKDLPAKKKYLCELCLDDVLYARTTSKLKTDNVFWGEHFEFHNLPPLRTVTVHLYRETDKKKKKERNSYLGLVSLPAASVAGRQFVEKWY--PVVTPNP-------------------KGGKGPGPMIRIKARYQTVSILPMEMYKEFAEHITNHYLGLCAALEPILSAKTKEEMASALVHILQSTGKVKDFLTDLMMSEVDRCGDNEHLIFRENTLATKAIEEYLKLVGQKYLQDALGEFIKALYESDENCEVDPSKCS----SADLPEHQGNLKMCCELAFCKIINSYCVFPRELKEVFASWRQECSSRGR------PDISERLISASLFLRFLCPAIMSPSLFNLLQEYPDDRTA-RTLTLIAKVTQNLANFAKF-GSKEEYMSFMNQFLEHEWTNMQRFLLEIS 472
BLAST of Disabled 2-interacting protein vs. Ensembl Mouse
Match: Dab2ip (disabled 2 interacting protein [Source:MGI Symbol;Acc:MGI:1916851]) HSP 1 Score: 303.138 bits (775), Expect = 4.414e-85 Identity = 178/446 (39.91%), Postives = 252/446 (56.50%), Query Frame = 3
Query: 861 CLSQPEMNEWLTKIKQRINPNYKNSTRHEDLLQIWIQEAKQLIQKKRYYCEIKLDEMLYGRTTIKTVTDTVFWGEEFEFRGLQNINKITICLYKMTDNKKKHERSELVAQIEVPCADLTDSSPCEKWYSPPFQYSNLRLSQSELTNSQKVKLDELLKNAVDIAPMIRIKGRYRPLEILPNKFYDSLSDFLVKQSIPLVESLESHLKVKSKEDFVKILLVILKSKDCHIDFLADLVFIEVSKAEDN--LILRGNSIASKAMECYLKMVGEKYLATILKDLINEVIFEEIDCEVDPLRLNNSKENSQIFENQNKLLRLVENVWSKIYHNAHLIPNELKLVFTKIREKLSETKRGSSYSSPMIYQ-VISSCLFLRFICPAIMSPFLFGLSNEYPDNVSINRTFTLIAKSIQSLANFSQFPQSKETYMEFMQNFINKNSSSMRSFLKLIS 2189
C S E ++W+ +++ ++PN NS R E +L++W+ EAK L KK+Y CE+ LD++LY RTT K TD VFWGE FEF L + +T+ LY+ TD KKK ER+ + + +P A + EKWY P N K PMIRIK RY+ + ILP + Y ++ + + L +LE L K+KE+ L+ IL+S DFL DL+ EV + DN LI R N++A+KA+E YLK+VG+KYL L + I + + +CEVDP + + ++ + E+Q L E + KI ++ + P ELK VF R++ S R P I + +IS+ LFLRF+CPAIMSP LF L EYPD+ + RT TLIAK Q+LANF++F SKE YM FM F+ ++M+ FL IS
Sbjct: 78 CRSAAERDKWMENLRRAVHPNKDNSRRVEHILKLWVIEAKDLPAKKKYLCELCLDDVLYARTTSKLKTDNVFWGEHFEFHNLPPLRTVTVHLYRETDKKKKKERNSYLGLVSLPAASVAGRQFVEKWY--PVVTPNP-------------------KGGKGPGPMIRIKARYQTVSILPMEMYKEFAEHITNHYLGLCAALEPILSAKTKEEMASALVHILQSTGKVKDFLTDLMMSEVDRCGDNEHLIFRENTLATKAIEEYLKLVGQKYLQDALGEFIKALYESDENCEVDPSKCS----SADLPEHQGNLKMCCELAFCKIINSYCVFPRELKEVFASWRQECSSRGR------PDISERLISASLFLRFLCPAIMSPSLFNLLQEYPDDRTA-RTLTLIAKVTQNLANFAKF-GSKEEYMSFMNQFLEHEWTNMQRFLLEIS 490
BLAST of Disabled 2-interacting protein vs. Ensembl Mouse
Match: Dab2ip (disabled 2 interacting protein [Source:MGI Symbol;Acc:MGI:1916851]) HSP 1 Score: 303.523 bits (776), Expect = 5.202e-85 Identity = 178/446 (39.91%), Postives = 252/446 (56.50%), Query Frame = 3
Query: 861 CLSQPEMNEWLTKIKQRINPNYKNSTRHEDLLQIWIQEAKQLIQKKRYYCEIKLDEMLYGRTTIKTVTDTVFWGEEFEFRGLQNINKITICLYKMTDNKKKHERSELVAQIEVPCADLTDSSPCEKWYSPPFQYSNLRLSQSELTNSQKVKLDELLKNAVDIAPMIRIKGRYRPLEILPNKFYDSLSDFLVKQSIPLVESLESHLKVKSKEDFVKILLVILKSKDCHIDFLADLVFIEVSKAEDN--LILRGNSIASKAMECYLKMVGEKYLATILKDLINEVIFEEIDCEVDPLRLNNSKENSQIFENQNKLLRLVENVWSKIYHNAHLIPNELKLVFTKIREKLSETKRGSSYSSPMIYQ-VISSCLFLRFICPAIMSPFLFGLSNEYPDNVSINRTFTLIAKSIQSLANFSQFPQSKETYMEFMQNFINKNSSSMRSFLKLIS 2189
C S E ++W+ +++ ++PN NS R E +L++W+ EAK L KK+Y CE+ LD++LY RTT K TD VFWGE FEF L + +T+ LY+ TD KKK ER+ + + +P A + EKWY P N K PMIRIK RY+ + ILP + Y ++ + + L +LE L K+KE+ L+ IL+S DFL DL+ EV + DN LI R N++A+KA+E YLK+VG+KYL L + I + + +CEVDP + + ++ + E+Q L E + KI ++ + P ELK VF R++ S R P I + +IS+ LFLRF+CPAIMSP LF L EYPD+ + RT TLIAK Q+LANF++F SKE YM FM F+ ++M+ FL IS
Sbjct: 127 CRSAAERDKWMENLRRAVHPNKDNSRRVEHILKLWVIEAKDLPAKKKYLCELCLDDVLYARTTSKLKTDNVFWGEHFEFHNLPPLRTVTVHLYRETDKKKKKERNSYLGLVSLPAASVAGRQFVEKWY--PVVTPNP-------------------KGGKGPGPMIRIKARYQTVSILPMEMYKEFAEHITNHYLGLCAALEPILSAKTKEEMASALVHILQSTGKVKDFLTDLMMSEVDRCGDNEHLIFRENTLATKAIEEYLKLVGQKYLQDALGEFIKALYESDENCEVDPSKCS----SADLPEHQGNLKMCCELAFCKIINSYCVFPRELKEVFASWRQECSSRGR------PDISERLISASLFLRFLCPAIMSPSLFNLLQEYPDDRTA-RTLTLIAKVTQNLANFAKF-GSKEEYMSFMNQFLEHEWTNMQRFLLEIS 539
BLAST of Disabled 2-interacting protein vs. Ensembl Mouse
Match: Dab2ip (disabled 2 interacting protein [Source:MGI Symbol;Acc:MGI:1916851]) HSP 1 Score: 303.908 bits (777), Expect = 5.269e-85 Identity = 178/446 (39.91%), Postives = 252/446 (56.50%), Query Frame = 3
Query: 861 CLSQPEMNEWLTKIKQRINPNYKNSTRHEDLLQIWIQEAKQLIQKKRYYCEIKLDEMLYGRTTIKTVTDTVFWGEEFEFRGLQNINKITICLYKMTDNKKKHERSELVAQIEVPCADLTDSSPCEKWYSPPFQYSNLRLSQSELTNSQKVKLDELLKNAVDIAPMIRIKGRYRPLEILPNKFYDSLSDFLVKQSIPLVESLESHLKVKSKEDFVKILLVILKSKDCHIDFLADLVFIEVSKAEDN--LILRGNSIASKAMECYLKMVGEKYLATILKDLINEVIFEEIDCEVDPLRLNNSKENSQIFENQNKLLRLVENVWSKIYHNAHLIPNELKLVFTKIREKLSETKRGSSYSSPMIYQ-VISSCLFLRFICPAIMSPFLFGLSNEYPDNVSINRTFTLIAKSIQSLANFSQFPQSKETYMEFMQNFINKNSSSMRSFLKLIS 2189
C S E ++W+ +++ ++PN NS R E +L++W+ EAK L KK+Y CE+ LD++LY RTT K TD VFWGE FEF L + +T+ LY+ TD KKK ER+ + + +P A + EKWY P N K PMIRIK RY+ + ILP + Y ++ + + L +LE L K+KE+ L+ IL+S DFL DL+ EV + DN LI R N++A+KA+E YLK+VG+KYL L + I + + +CEVDP + + ++ + E+Q L E + KI ++ + P ELK VF R++ S R P I + +IS+ LFLRF+CPAIMSP LF L EYPD+ + RT TLIAK Q+LANF++F SKE YM FM F+ ++M+ FL IS
Sbjct: 184 CRSAAERDKWMENLRRAVHPNKDNSRRVEHILKLWVIEAKDLPAKKKYLCELCLDDVLYARTTSKLKTDNVFWGEHFEFHNLPPLRTVTVHLYRETDKKKKKERNSYLGLVSLPAASVAGRQFVEKWY--PVVTPNP-------------------KGGKGPGPMIRIKARYQTVSILPMEMYKEFAEHITNHYLGLCAALEPILSAKTKEEMASALVHILQSTGKVKDFLTDLMMSEVDRCGDNEHLIFRENTLATKAIEEYLKLVGQKYLQDALGEFIKALYESDENCEVDPSKCS----SADLPEHQGNLKMCCELAFCKIINSYCVFPRELKEVFASWRQECSSRGR------PDISERLISASLFLRFLCPAIMSPSLFNLLQEYPDDRTA-RTLTLIAKVTQNLANFAKF-GSKEEYMSFMNQFLEHEWTNMQRFLLEIS 596
BLAST of Disabled 2-interacting protein vs. Ensembl Mouse
Match: Dab2ip (disabled 2 interacting protein [Source:MGI Symbol;Acc:MGI:1916851]) HSP 1 Score: 303.523 bits (776), Expect = 6.272e-85 Identity = 178/446 (39.91%), Postives = 252/446 (56.50%), Query Frame = 3
Query: 861 CLSQPEMNEWLTKIKQRINPNYKNSTRHEDLLQIWIQEAKQLIQKKRYYCEIKLDEMLYGRTTIKTVTDTVFWGEEFEFRGLQNINKITICLYKMTDNKKKHERSELVAQIEVPCADLTDSSPCEKWYSPPFQYSNLRLSQSELTNSQKVKLDELLKNAVDIAPMIRIKGRYRPLEILPNKFYDSLSDFLVKQSIPLVESLESHLKVKSKEDFVKILLVILKSKDCHIDFLADLVFIEVSKAEDN--LILRGNSIASKAMECYLKMVGEKYLATILKDLINEVIFEEIDCEVDPLRLNNSKENSQIFENQNKLLRLVENVWSKIYHNAHLIPNELKLVFTKIREKLSETKRGSSYSSPMIYQ-VISSCLFLRFICPAIMSPFLFGLSNEYPDNVSINRTFTLIAKSIQSLANFSQFPQSKETYMEFMQNFINKNSSSMRSFLKLIS 2189
C S E ++W+ +++ ++PN NS R E +L++W+ EAK L KK+Y CE+ LD++LY RTT K TD VFWGE FEF L + +T+ LY+ TD KKK ER+ + + +P A + EKWY P N K PMIRIK RY+ + ILP + Y ++ + + L +LE L K+KE+ L+ IL+S DFL DL+ EV + DN LI R N++A+KA+E YLK+VG+KYL L + I + + +CEVDP + + ++ + E+Q L E + KI ++ + P ELK VF R++ S R P I + +IS+ LFLRF+CPAIMSP LF L EYPD+ + RT TLIAK Q+LANF++F SKE YM FM F+ ++M+ FL IS
Sbjct: 156 CRSAAERDKWMENLRRAVHPNKDNSRRVEHILKLWVIEAKDLPAKKKYLCELCLDDVLYARTTSKLKTDNVFWGEHFEFHNLPPLRTVTVHLYRETDKKKKKERNSYLGLVSLPAASVAGRQFVEKWY--PVVTPNP-------------------KGGKGPGPMIRIKARYQTVSILPMEMYKEFAEHITNHYLGLCAALEPILSAKTKEEMASALVHILQSTGKVKDFLTDLMMSEVDRCGDNEHLIFRENTLATKAIEEYLKLVGQKYLQDALGEFIKALYESDENCEVDPSKCS----SADLPEHQGNLKMCCELAFCKIINSYCVFPRELKEVFASWRQECSSRGR------PDISERLISASLFLRFLCPAIMSPSLFNLLQEYPDDRTA-RTLTLIAKVTQNLANFAKF-GSKEEYMSFMNQFLEHEWTNMQRFLLEIS 568
BLAST of Disabled 2-interacting protein vs. UniProt/SwissProt
Match: sp|Q8MLZ5|GAP2_CAEEL (Ras GTPase-activating protein gap-2 OS=Caenorhabditis elegans OX=6239 GN=gap-2 PE=2 SV=2) HSP 1 Score: 313.153 bits (801), Expect = 5.006e-87 Identity = 171/450 (38.00%), Postives = 267/450 (59.33%), Query Frame = 3
Query: 861 CLSQPEMNEWLTKIKQRINPNYKNSTRHEDLLQIWIQEAKQLIQKKRYYCEIKLDEMLYGRTTIKTVTDTVFWGEEFEFRGLQNINKITICLYKMTDNKKKHERSELVAQIEVPCADLTDSSPCEKWYSPPFQYSNLRLSQSELTNSQKVKLDELLKNAVDIAPMIRIKGRYRPLEILPNKFYDSLSDFLVKQSIPLVESLESHLKVKSKEDFVKILLVILKSKDCHIDFLADLVFIEVSKAE-DNLILRGNSIASKAMECYLKMVGEKYLATILKDLINEVIFEEIDCEVDPLRLNNSKENSQIFENQNKLLRLVENVWSKIYHNAHLIPNELKLVFTKIREKLSETKRGSSYSSPMIYQVISSCLFLRFICPAIMSPFLFGLSNEYPDNVSINRTFTLIAKSIQSLANFSQFPQSKETYMEFMQNFINKNSSSMRSFLKLISLNKSNG 2207
C + E +W+ +++ +NP R E+ + IWI EAK L K++YYCE+ LD+ LY +T+ K TD VFWGE FEF L I+++ + L++ +D+KKK + L+ + + L+ SP E+WY+ +S+ + + ++ K++ +P +RIK R++ + ILP + YD+L + L +PL E LE L V+ KED L+ ++ + +FL DL+ EV K + D+L+ RGN++A+KAME ++K+V + YL + L D I V+ E CEVDP +L N NS + +N+ L+R VE W+KI +N H +P L+ VF+ +R +L R + + +ISS +FLRF+CPAI+SP LF L +EYP + R TLIAK++Q+LANFS+F KE +MEFM F+++ M+ FL IS +G
Sbjct: 365 CRTPLERAKWMENLRKTMNPRRDQQRRTENSMLIWILEAKGLPAKRKYYCEMTLDKTLYAKTSSKARTDNVFWGENFEFMMLPKIDEVCVSLFRESDSKKK--KDTLIGYVTIGIDQLSSRSPVERWYTVNTSHSD--------SGTSRIASALGGKSSSQESPSLRIKARWQSVHILPLRAYDNLLETLCYNYLPLCEQLEPVLNVRDKEDLATSLVRVMYKHNLAKEFLCDLIMKEVEKLDNDHLMFRGNTLATKAMESFMKLVADDYLDSTLSDFIKTVLQCEDSCEVDPQKLGNV-SNSSLEKNRALLMRYVEVAWTKILNNVHQLPKNLRDVFSALRCRLEAQNREA-----LADTLISSSIFLRFLCPAILSPSLFNLVSEYPSPTNA-RNLTLIAKTLQNLANFSKF-GGKEPHMEFMNEFVDREWHRMKDFLLRISSESKSG 796
BLAST of Disabled 2-interacting protein vs. UniProt/SwissProt
Match: sp|Q8T498|GAP2_DROME (Ras GTPase-activating protein raskol OS=Drosophila melanogaster OX=7227 GN=raskol PE=1 SV=3) HSP 1 Score: 315.079 bits (806), Expect = 1.387e-86 Identity = 162/444 (36.49%), Postives = 264/444 (59.46%), Query Frame = 3
Query: 861 CLSQPEMNEWLTKIKQRINPNYKNSTRHEDLLQIWIQEAKQLIQKKRYYCEIKLDEMLYGRTTIKTVTDTVFWGEEFEFRGLQNINKITICLYKMTDNKKKHERSELVAQIEVPCADLTDSSPCEKWYSPPFQYSNLRLSQSELTNSQKVKLDELLKNAVDIAPMIRIKGRYRPLEILPNKFYDSLSDFLVKQSIPLVESLESHLKVKSKEDFVKILLVILKSKDCHIDFLADLVFIEVSKAEDN-LILRGNSIASKAMECYLKMVGEKYLATILKDLINEVIFEEIDCEVDPLRLNNSKENSQIFENQNKLLRLVENVWSKIYHNAHLIPNELKLVFTKIREKLSETKRGSSYSSPMIYQVISSCLFLRFICPAIMSPFLFGLSNEYPDNVSINRTFTLIAKSIQSLANFSQFPQSKETYMEFMQNFINKNSSSMRSFLKLIS 2189
C S+ E + W+ +++ I PN +++ R ++ L++W+ EAK L KKRY+CE++LD+ LYGRT++K TD +FWGE F+F + IN IT+ +++ D KKK ++ + V +++P D+T PCE+WY + L ++ K E L P +RIK R++ +ILP Y + +L + + E+LE + VK+KED + L++++ ++ FL D+V +++ + D L RGNS+A+K+ME +LK+ GE+YL L INE+I E DCEVDP + + S S + Q L V W I+ + P +L+ F RE+L + R M +IS+ +FLRF+CPAI+SP LF +++E P + R TL+AK++Q+LANF++F Q KE +MEF+ +F+ + ++ M+ FL++IS
Sbjct: 273 CGSRQERDLWIYSLRKSIAPNAEHTRRTDNSLKMWVYEAKNLPPKKRYFCELQLDKTLYGRTSVKLQTDLLFWGEHFDFPDIPEINVITVNVFREVDKKKKRDKYQFVGSVKIPVHDVTSRLPCEQWYPILSDKAGDSLGRTSGGGGSGSKDKEQL-------PTLRIKCRFQSTDILPINVYGNFLTYLKENYKRVCETLEPVIGVKAKEDIGQALVLLMHAQGLAGAFLTDVVALDLLRVGDQRLTFRGNSLATKSMEAFLKLTGEQYLQDTLSAPINELIQSERDCEVDPTKTSGSSAGS-LQRQQAALRGAVRGAWQCIFESHKHFPAQLRNCFATFRERLQQLGR-----QDMADNLISASIFLRFLCPAILSPSLFNITSELP-SARATRNLTLVAKTLQTLANFTRF-QGKENFMEFLNDFLEQEAARMQQFLEIIS 701
BLAST of Disabled 2-interacting protein vs. UniProt/SwissProt
Match: sp|Q3UHC7|DAB2P_MOUSE (Disabled homolog 2-interacting protein OS=Mus musculus OX=10090 GN=Dab2ip PE=1 SV=1) HSP 1 Score: 303.908 bits (777), Expect = 5.452e-84 Identity = 178/446 (39.91%), Postives = 252/446 (56.50%), Query Frame = 3
Query: 861 CLSQPEMNEWLTKIKQRINPNYKNSTRHEDLLQIWIQEAKQLIQKKRYYCEIKLDEMLYGRTTIKTVTDTVFWGEEFEFRGLQNINKITICLYKMTDNKKKHERSELVAQIEVPCADLTDSSPCEKWYSPPFQYSNLRLSQSELTNSQKVKLDELLKNAVDIAPMIRIKGRYRPLEILPNKFYDSLSDFLVKQSIPLVESLESHLKVKSKEDFVKILLVILKSKDCHIDFLADLVFIEVSKAEDN--LILRGNSIASKAMECYLKMVGEKYLATILKDLINEVIFEEIDCEVDPLRLNNSKENSQIFENQNKLLRLVENVWSKIYHNAHLIPNELKLVFTKIREKLSETKRGSSYSSPMIYQ-VISSCLFLRFICPAIMSPFLFGLSNEYPDNVSINRTFTLIAKSIQSLANFSQFPQSKETYMEFMQNFINKNSSSMRSFLKLIS 2189
C S E ++W+ +++ ++PN NS R E +L++W+ EAK L KK+Y CE+ LD++LY RTT K TD VFWGE FEF L + +T+ LY+ TD KKK ER+ + + +P A + EKWY P N K PMIRIK RY+ + ILP + Y ++ + + L +LE L K+KE+ L+ IL+S DFL DL+ EV + DN LI R N++A+KA+E YLK+VG+KYL L + I + + +CEVDP + + ++ + E+Q L E + KI ++ + P ELK VF R++ S R P I + +IS+ LFLRF+CPAIMSP LF L EYPD+ + RT TLIAK Q+LANF++F SKE YM FM F+ ++M+ FL IS
Sbjct: 184 CRSAAERDKWMENLRRAVHPNKDNSRRVEHILKLWVIEAKDLPAKKKYLCELCLDDVLYARTTSKLKTDNVFWGEHFEFHNLPPLRTVTVHLYRETDKKKKKERNSYLGLVSLPAASVAGRQFVEKWY--PVVTPNP-------------------KGGKGPGPMIRIKARYQTVSILPMEMYKEFAEHITNHYLGLCAALEPILSAKTKEEMASALVHILQSTGKVKDFLTDLMMSEVDRCGDNEHLIFRENTLATKAIEEYLKLVGQKYLQDALGEFIKALYESDENCEVDPSKCS----SADLPEHQGNLKMCCELAFCKIINSYCVFPRELKEVFASWRQECSSRGR------PDISERLISASLFLRFLCPAIMSPSLFNLLQEYPDDRTA-RTLTLIAKVTQNLANFAKF-GSKEEYMSFMNQFLEHEWTNMQRFLLEIS 596
BLAST of Disabled 2-interacting protein vs. UniProt/SwissProt
Match: sp|Q5VWQ8|DAB2P_HUMAN (Disabled homolog 2-interacting protein OS=Homo sapiens OX=9606 GN=DAB2IP PE=1 SV=2) HSP 1 Score: 303.138 bits (775), Expect = 9.174e-84 Identity = 178/446 (39.91%), Postives = 251/446 (56.28%), Query Frame = 3
Query: 861 CLSQPEMNEWLTKIKQRINPNYKNSTRHEDLLQIWIQEAKQLIQKKRYYCEIKLDEMLYGRTTIKTVTDTVFWGEEFEFRGLQNINKITICLYKMTDNKKKHERSELVAQIEVPCADLTDSSPCEKWYSPPFQYSNLRLSQSELTNSQKVKLDELLKNAVDIAPMIRIKGRYRPLEILPNKFYDSLSDFLVKQSIPLVESLESHLKVKSKEDFVKILLVILKSKDCHIDFLADLVFIEVSKAEDN--LILRGNSIASKAMECYLKMVGEKYLATILKDLINEVIFEEIDCEVDPLRLNNSKENSQIFENQNKLLRLVENVWSKIYHNAHLIPNELKLVFTKIREKLSETKRGSSYSSPMIYQ-VISSCLFLRFICPAIMSPFLFGLSNEYPDNVSINRTFTLIAKSIQSLANFSQFPQSKETYMEFMQNFINKNSSSMRSFLKLIS 2189
C S E ++W+ +++ ++PN NS R E +L++W+ EAK L KK+Y CE+ LD++LY RTT K TD VFWGE FEF L + +T+ LY+ TD KKK ER+ + + +P A + EKWY P N K PMIRIK RY+ + ILP + Y ++ + + L +LE L K+KE+ L+ IL+S DFL DL+ EV + DN LI R N++A+KA+E YLK+VG+KYL L + I + + +CEVDP + + + + E+Q L E + KI ++ + P ELK VF R++ S R P I + +IS+ LFLRF+CPAIMSP LF L EYPD+ + RT TLIAK Q+LANF++F SKE YM FM F+ ++M+ FL IS
Sbjct: 184 CRSAAERDKWMENLRRAVHPNKDNSRRVEHILKLWVIEAKDLPAKKKYLCELCLDDVLYARTTGKLKTDNVFWGEHFEFHNLPPLRTVTVHLYRETDKKKKKERNSYLGLVSLPAASVAGRQFVEKWY--PVVTPNP-------------------KGGKGPGPMIRIKARYQTITILPMEMYKEFAEHITNHYLGLCAALEPILSAKTKEEMASALVHILQSTGKVKDFLTDLMMSEVDRCGDNEHLIFRENTLATKAIEEYLKLVGQKYLQDALGEFIKALYESDENCEVDPSKCS----AADLPEHQGNLKMCCELAFCKIINSYCVFPRELKEVFASWRQECSSRGR------PDISERLISASLFLRFLCPAIMSPSLFNLLQEYPDDRTA-RTLTLIAKVTQNLANFAKF-GSKEEYMSFMNQFLEHEWTNMQRFLLEIS 596
BLAST of Disabled 2-interacting protein vs. UniProt/SwissProt
Match: sp|Q6P730|DAB2P_RAT (Disabled homolog 2-interacting protein OS=Rattus norvegicus OX=10116 GN=Dab2ip PE=1 SV=1) HSP 1 Score: 292.352 bits (747), Expect = 4.598e-81 Identity = 174/433 (40.18%), Postives = 244/433 (56.35%), Query Frame = 3
Query: 900 IKQRINPNYKNSTRHEDLLQIWIQEAKQLIQKKRYYCEIKLDEMLYGRTTIKTVTDTVFWGEEFEFRGLQNINKITICLYKMTDNKKKHERSELVAQIEVPCADLTDSSPCEKWYSPPFQYSNLRLSQSELTNSQKVKLDELLKNAVDIAPMIRIKGRYRPLEILPNKFYDSLSDFLVKQSIPLVESLESHLKVKSKEDFVKILLVILKSKDCHIDFLADLVFIEVSKAEDN--LILRGNSIASKAMECYLKMVGEKYLATILKDLINEVIFEEIDCEVDPLRLNNSKENSQIFENQNKLLRLVENVWSKIYHNAHLIPNELKLVFTKIREKLSETKRGSSYSSPMIYQ-VISSCLFLRFICPAIMSPFLFGLSNEYPDNVSINRTFTLIAKSIQSLANFSQFPQSKETYMEFMQNFINKNSSSMRSFLKLIS 2189
+++ ++PN NS R E +L++W+ EAK L KK+Y CE+ LD++LY RTT K TD VFWGE FEF L + +T+ LY+ TD KKK ER+ + + +P A + EKWY P N K PMIRIK RY+ + ILP + Y ++ + + L +LE L K+KE+ L+ IL+S DFL DL+ EV + DN LI R N++A+KA+E YLK+VG+KYL L + I + + +CEVDP + + + + E+Q L E + KI ++ + P ELK VF R++ S R P I + +IS+ LFLRF+CPAIMSP LF L EYPD+ + RT TLIAK Q+LANF++F SKE YM FM F+ ++M+ FL IS
Sbjct: 4 LRRAVHPNKDNSRRVEHILKLWVIEAKDLPAKKKYLCELCLDDVLYARTTGKLKTDNVFWGEHFEFHNLPPLRTVTVHLYRETDKKKKKERNSYLGLVSLPAASVAGRQFVEKWY--PVVTPNP-------------------KGGKGPGPMIRIKARYQTITILPMEMYKEFAEHITNHYLGLCAALEPILSAKTKEEMASALVHILQSTGKVKDFLTDLMMSEVDRCGDNEHLIFRENTLATKAIEEYLKLVGQKYLQDALGEFIKALYESDENCEVDPSKCS----AADLPEHQGNLKMCCELAFCKIINSYCVFPRELKEVFASWRQECSSRGR------PDISERLISASLFLRFLCPAIMSPSLFNLLQEYPDDRTA-RTLTLIAKVTQNLANFAKF-GSKEEYMSFMNQFLEHEWTNMQRFLLEIS 403
BLAST of Disabled 2-interacting protein vs. TrEMBL
Match: A0A0N4WQW6 (Ras-GAP domain-containing protein OS=Haemonchus placei OX=6290 GN=HPLM_LOCUS13836 PE=4 SV=1) HSP 1 Score: 323.553 bits (828), Expect = 1.501e-91 Identity = 175/445 (39.33%), Postives = 262/445 (58.88%), Query Frame = 3
Query: 873 PEMNEWLTKIKQRINPNYKNSTRHEDLLQIWIQEAKQLIQKKRYYCEIKLDEMLYGRTTIKTVTDTVFWGEEFEFRGLQNINKITICLYKMTDNKKKHERSELVAQIEVPCADLTDSSPCEKWYS-PPFQYSNLRLSQSELTNSQKVKLDELLKNAVDIAPMIRIKGRYRPLEILPNKFYDSLSDFLVKQSIPLVESLESHLKVKSKEDFVKILLVILKSKDCHIDFLADLVFIEVSKAE-DNLILRGNSIASKAMECYLKMVGEKYLATILKDLINEVIFEEIDCEVDPLRLNNSKENSQIFENQNKLLRLVENVWSKIYHNAHLIPNELKLVFTKIREKLSETKRGSSYSSPMIYQVISSCLFLRFICPAIMSPFLFGLSNEYPDNVSINRTFTLIAKSIQSLANFSQFPQSKETYMEFMQNFINKNSSSMRSFLKLISLNKS 2201
P + ++ +++ +NP R E+ LQ+W+ EAK + K+RYYCE+ LD+ LY RT+ K + D VFWGE F+F LQ ++++ I LY+ D KKK ER+ L+ I + L+ P E+WY+ + RL+ + T S +L P +RIK R++ + ILP + YD +L + L LE L VK+KED L+ +L + DFL +LV EV + D+L+ RGNS+A+KAME Y+K++ ++YL ++L D ++ V+ CEVDPL+LN S + +N+ +L RLVE W KI ++ P EL+LVF +R++L R S + +ISS +FLR++CPAI+SP LF L EYP V+ R TLIAK++Q+LANF++F KE YMEFM F+ + M+ FL+ IS +S
Sbjct: 25 PTLKVTISSLRRTMNPRRDAQRRVENALQLWVLEAKGVPAKRRYYCELCLDKTLYARTSSKPLVDNVFWGEHFDFTMLQKMDEVCINLYREGDPKKKKERATLIGYILIAIEQLSSRHPVERWYTVTTTSDTGNRLASALSTKSTNQEL-----------PAVRIKARWQSISILPLRAYDDFLHYLSCNYLSLCNHLEPVLSVKAKEDLATALVRVLHKQKLANDFLCELVMSEVDSLDNDHLMFRGNSLATKAMEAYMKLIADEYLQSVLGDFVHNVLSSNETCEVDPLKLNGVS-TSTLDKNRAQLTRLVELAWEKIINSTSAFPMELRLVFGSLRDRLESQGRSS-----LADTLISSSIFLRYLCPAILSPSLFNLVTEYPSGVTA-RNLTLIAKTLQNLANFTKF-GGKEHYMEFMNGFVEREWQRMKDFLRRISTGQS 450
BLAST of Disabled 2-interacting protein vs. TrEMBL
Match: W2T147 (C2 domain protein OS=Necator americanus OX=51031 GN=NECAME_03697 PE=4 SV=1) HSP 1 Score: 320.857 bits (821), Expect = 6.958e-90 Identity = 175/431 (40.60%), Postives = 253/431 (58.70%), Query Frame = 3
Query: 912 INPNYKNSTRHEDLLQIWIQEAKQLIQKKRYYCEIKLDEMLYGRTTIKTVTDTVFWGEEFEFRGLQNINKITICLYKMTDNKKKHERSELVAQIEVPCADLTDSSPCEKWYSPPFQYSNLRLSQSELTNSQKVKLDELLKNAVDIAPMIRIKGRYRPLEILPNKFYDSLSDFLVKQSIPLVESLESHLKVKSKEDFVKILLVILKSKDCHIDFLADLVFIEVSKAE-DNLILRGNSIASKAMECYLKMVGEKYLATILKDLINEVIFEEIDCEVDPLRLNNSKENSQIFENQNKLLRLVENVWSKIYHNAHLIPNELKLVFTKIREKLSETKRGSSYSSPMIYQVISSCLFLRFICPAIMSPFLFGLSNEYPDNVSINRTFTLIAKSIQSLANFSQFPQSKETYMEFMQNFINKNSSSMRSFLKLISLNKS 2201
+NP R E+ LQ+W+ EAK + K+RYYCE+ LD+ LY RT+ K + D VFWGE F+F LQ ++++ I LY+ D KKK ERS L+ I + L+ P E+WY+ + SE N L K+A P +RIK R++ + ILP + YD +L +PL LE L V++KED L+ +L + DFL +LV EV + D+L+ RGNS+A+KAME Y+K++ ++YL ++L + I V+ CEVDPL+LN + S + +N+ L RLVE W +I + P EL++VF +RE+L R S + +ISS +FLR++CPAI+SP LF L EYP V+ R TLIAK++Q+LANF++F KE YMEFM F+ + M+ FL+ IS +S
Sbjct: 1 MNPRRDAQRRVENALQLWVLEAKGVPAKRRYYCELCLDKTLYARTSSKPLVDNVFWGEHFDFTMLQKMDEVCINLYREGDPKKKKERSTLIGYILIAIEQLSSRHPVERWYT--------VTTTSESGNRLASALG--TKSANQEQPAVRIKARWQSIGILPLRAYDDFLHYLSCNYLPLCIHLEPVLTVRAKEDLATALVRVLHKQKLANDFLCELVMSEVDSLDNDHLMFRGNSLATKAMEAYMKLIADEYLQSVLGEFIQNVLSSNESCEVDPLKLNGAS-TSTLEKNRIHLTRLVELAWDRIIGSTSAFPMELRMVFGSLRERLESQGRSS-----LADTLISSSIFLRYLCPAILSPSLFNLVTEYPSGVTA-RNLTLIAKTLQNLANFTKF-GGKEHYMEFMNGFVEREWQRMKDFLRRISTGQS 413
BLAST of Disabled 2-interacting protein vs. TrEMBL
Match: A0A0N4ZZ53 (Ras-GAP domain-containing protein OS=Parastrongyloides trichosuri OX=131310 PE=4 SV=1) HSP 1 Score: 326.25 bits (835), Expect = 1.791e-89 Identity = 179/448 (39.96%), Postives = 270/448 (60.27%), Query Frame = 3
Query: 861 CLSQPEMNEWLTKIKQRINPNYKNSTRHEDLLQIWIQEAKQLIQKKRYYCEIKLDEMLYGRTTIKTVTDTVFWGEEFEFRGLQNINKITICLYKMTDNKKKHERSELVAQIEVPCADLTDSSPCEKWYSPPFQYSNLRLSQSELTNSQKVKLDELLKNAVDIAPMIRIKGRYRPLEILPNKFYDSLSDFLVKQSIPLVESLESHLKVKSKEDFVKILLVILKSKDCHIDFLADLVFIEVSKAE-DNLILRGNSIASKAMECYLKMVGEKYLATILKDLINEVIFEEIDCEVDPLRLNNSKENSQIFENQNKLLRLVENVWSKIYHNAHLIPNELKLVFTKIREKLSETKRGSSYSSPMIYQVISSCLFLRFICPAIMSPFLFGLSNEYPDNVSINRTFTLIAKSIQSLANFSQFPQSKETYMEFMQNFINKNSSSMRSFLKLISLNKS 2201
C +Q E +W+ +++ +NP S R E+ LQIW+ EAK + K+ Y+CEI LD+ LY RT+ K +D FWGE F+F L N+ + I LYK D+KK+ +R+ LV +++ L P E+WY+ +++ +N K+ + + K + + A IR+K R++ +++LP YD L F+ + +PL +LE L VK+KEDF L+ +L + C +FL DL+ EV + ++L+ RGNS+A+KAME Y+K+V + YL L D I V+ +CEVDP++L NS N + N+ +L+ L E WSKI + P ELK VF +R +L + RG + +ISS +FLR++CPAI+SP LF L +E+P N ++R TLIAK+IQ+LANF++F KE YMEFM +F+ + +M SFL IS N S
Sbjct: 178 CRTQSERAKWIENLRRTMNPRRDQSRRTENALQIWVLEAKGIQSKRNYFCEICLDKTLYARTSSKPKSDICFWGEYFDFSMLPNVEDVCINLYKEADSKKRKDRTTLVGYVQIKMDQLLSRYPVERWYT-------VKVGSEGFSN--KLTSNWVSKTSSEQAS-IRVKARFQTVDVLPMHVYDHLLYFIKENYLPLCLALEPMLSVKAKEDFANSLVKVLHKQRCVKEFLCDLIMSEVDVLDNEHLMFRGNSLATKAMEGYMKLVADDYLQETLGDFIKMVLEGNDNCEVDPMKLPNSSSN-LLDRNRQQLIFLCEAAWSKIIVSLKFFPTELKQVFDLLRRRLIASNRGE-----LADNLISSSIFLRYLCPAILSPSLFSLVSEFP-NPQVSRNLTLIAKTIQTLANFNKF-GGKEHYMEFMNDFVTREWDNMHSFLLKISSNNS 607
BLAST of Disabled 2-interacting protein vs. TrEMBL
Match: A0A482WUJ0 (Uncharacterized protein OS=Laodelphax striatellus OX=195883 GN=LSTR_LSTR012709 PE=4 SV=1) HSP 1 Score: 320.472 bits (820), Expect = 1.945e-89 Identity = 188/553 (34.00%), Postives = 301/553 (54.43%), Query Frame = 3
Query: 861 CLSQPEMNEWLTKIKQRINPNYKNSTRHEDLLQIWIQEAKQLIQKKRYYCEIKLDEMLYGRTTIKTVTDTVFWGEEFEFRGLQNINKITICLYKMTDNKKKHERSELVAQIEVPCADLTDSSPCEKWYSPPFQYSNLRLSQSELTNSQKVKLDELLKNAVDIAPMIRIKGRYRPLEILPNKFYDSLSDFLVKQSIPLVESLESHLKVKSKEDFVKILLVILKSKDCHIDFLADLVFIEVSKAED-NLILRGNSIASKAMECYLKMVGEKYLATILKDLI-NEVIFEEIDCEVDPLRLNNSKENSQIFENQNKLLRLVENVWSKIYHNAHLIPNELKLVFTKIREKLSETKRGSSYSSPMIYQVISSCLFLRFICPAIMSPFLFGLSNEYPDNVSINRTFTLIAKSIQSLANFSQFPQSKETYMEFMQNFINKNSSSMRSFLKLISLNKSNGAKSMESQDVLYLLLETDKINYSPTKD-DRYIDIGYHLAELMFQLNIHLKDIPDKEYTPTLTEARTIIENI----------TKLSVHNESDCESDSSNISNFN 2480
C + E ++W+ +++ + P+ +++ R ++ L+IWI EAK + KKRY+CE+ LD+ LY RT++K + FWGE F+F L +N I+I LY+ D KKK +++ LV + +P D+T EKWY SE K A+ P +RIK R++ ++ILP + Y +L + E LE + VK+KED L+ +++ + +FL D+V +++ + ED L RGNS+A+KAME YLK+ GE+YL T LKDL+ + DCEVDPL+ + + + NQ L VE W+KI + P EL+ F +RE+L+ + R + +IS+C+FLRF+CPAI+SP LF +++EYP N R TL+AK++Q+LANF++F Q KE +MEFM +F+ + + +M++FL +IS S +T + + D DRYID+G L+ L L+ + + +++ +++ + T L V+ +C+S NI FN
Sbjct: 123 CRTAEERDKWVYSLRKTVQPDQEHTRRTDNSLKIWILEAKGVPNKKRYFCELCLDKTLYARTSVKQKGELCFWGEHFDFLNLPLVNMISINLYREADRKKKRDKNVLVGSVSIPVHDVTSRYLTEKWYP----------VVSE-------------KGALKDPPALRIKCRFQKVDILPVRVYQEFLQYLKSDYKSICEVLEPVIGVKAKEDIATALVHVMQRERLAKEFLTDIVMMDIERIEDERLTFRGNSLATKAMEAYLKLTGEQYLHTTLKDLVTGGGVLAGGDCEVDPLK---AGSGAALARNQANLRNAVETTWAKILASHAQFPVELRQCFQMLRERLTASCRMD-----ICDNLISACIFLRFLCPAILSPSLFNITSEYP-NEKAARNLTLVAKTLQTLANFTRF-QGKENFMEFMNDFLEREAPAMKNFLHMISSGVSK---------------DTSQCGGTVGSDLDRYIDLGKQLSILHALLSECVAKVSAARAN-EVSQLHCVLDRVQGALADPIARTDLVVNGGGNCQSLQRNIFRFN 626
BLAST of Disabled 2-interacting protein vs. TrEMBL
Match: A0A2R5LKT9 (Putative gtpase-activating protein (Fragment) OS=Ornithodoros turicata OX=34597 PE=4 SV=1) HSP 1 Score: 321.627 bits (823), Expect = 1.183e-88 Identity = 173/444 (38.96%), Postives = 259/444 (58.33%), Query Frame = 3
Query: 861 CLSQPEMNEWLTKIKQRINPNYKNSTRHEDLLQIWIQEAKQLIQKKRYYCEIKLDEMLYGRTTIKTVTDTVFWGEEFEFRGLQNINKITICLYKMTDNKKKHERSELVAQIEVPCADLTDSSPCEKWYSPPFQYSNLRLSQSELTNSQKVKLDELLKNAVDIAPMIRIKGRYRPLEILPNKFYDSLSDFLVKQSIPLVESLESHLKVKSKEDFVKILLVILKSKDCHIDFLADLVFIEVSKAED-NLILRGNSIASKAMECYLKMVGEKYLATILKDLINEVIFEEIDCEVDPLRLNNSKENSQIFENQNKLLRLVENVWSKIYHNAHLIPNELKLVFTKIREKLSETKRGSSYSSPMIYQVISSCLFLRFICPAIMSPFLFGLSNEYPDNVSINRTFTLIAKSIQSLANFSQFPQSKETYMEFMQNFINKNSSSMRSFLKLIS 2189
C + E W+ +I++ I PN + R E+ L++WI E K + KKRY+CE+ LD+ LY RT K ++ FWGE FEF L N+ IT+ LY+ D KK+ E+S L+ +++P + + P EKWY V +++ N P +RIK RY LEILP K Y + +L Q L + LE + V+ KE+ L+ +++ ++ +FL +V ++ K +D +L RGNS+A+KAME Y+K++GEKYL L D++ V+ DCEVDP+++ N N + +Q +L+ VE W KI ++A P ELK VF RE+L + + +IS+ +FLRF+CPAI+SP LFGL+ EYP + +R TLIAK+IQ+LANF++F KE YMEFM +F+ K S+M++FL+ IS
Sbjct: 137 CRTGHEYRSWMHRIRRTIEPNEEMMRRKENCLRLWILEGKGIATKKRYFCELCLDDTLYARTASKQKSNICFWGEHFEFTNLPNVTTITVHLYREADKKKRREKSTLIGSVDIPVSAVNSRHPTEKWYP--------------------VTMEK--ANGGKDCPSLRIKCRYHTLEILPLKTYANFLQYLKTQYQSLCDLLEPAISVRIKEEIATALVHVMQKENIAREFLTGVVMSDIDKIDDQHLTFRGNSLATKAMEAYMKLLGEKYLQDTLGDVVRTVVDSSEDCEVDPIKVPN---NVVLQRHQGRLMSYVEMAWLKIINSAPSFPVELKDVFHTYRERLVAAGK-----EDLCDNLISASIFLRFLCPAILSPSLFGLTTEYPGERA-SRNLTLIAKTIQTLANFTKF-GGKENYMEFMNDFVEKEWSTMKTFLRQIS 548
BLAST of Disabled 2-interacting protein vs. Ensembl Cavefish
Match: syngap1b (synaptic Ras GTPase activating protein 1b [Source:ZFIN;Acc:ZDB-GENE-100921-2]) HSP 1 Score: 300.827 bits (769), Expect = 1.513e-83 Identity = 178/445 (40.00%), Postives = 254/445 (57.08%), Query Frame = 3
Query: 861 CLSQPEMNEWLTKIKQRINPNYKNSTRHEDLLQIWIQEAKQLIQKKRYYCEIKLDEMLYGRTTIKTVTDTVFWGEEFEFRGLQNINKITICLYKMTDNKKKHERSELVAQIEVPCADLTDSSPCEKWYSPPFQYSNLRLSQSELTNSQKVKLDELLKNAVDIAPMIRIKGRYRPLEILPNKFYDSLSDFLVKQSIPLVESLESHLKVKSKEDFVKILLVILKSKDCHIDFLADLVFIEVSKAED--NLILRGNSIASKAMECYLKMVGEKYLATILKDLINEVIFEEIDCEVDPLRLNNSKENSQIFENQNKLLRLVENVWSKIYHNAHLIPNELKLVFTKIREKLSETKRGSSYSSPMIYQVISSCLFLRFICPAIMSPFLFGLSNEYPDNVSINRTFTLIAKSIQSLANFSQFPQSKETYMEFMQNFINKNSSSMRSFLKLIS 2189
C S E ++W+ +++ + PN NS R +++L++WI EA++L KKRYYCE+ LD+MLY RTT K TDTVFWGE FEF L + + + LYK TD K++ E+S + + +P + +T E+WY P Q S L++ K+ I +R+K RY+ + ILP + Y ++++ L LE L VKSKE+ L+ IL+S DFL+D+ EV + D +LI R N++A+KA+E YLK++G KYL L D I + E +CEVDP+R S + ++Q L E KI ++ + P ELK VF R + +E R + ++IS LFLRF+CPA+MSP LF L+ EYPD +RT TLIAK +Q+LANFS+F SKE YM FM F+ SM+ FL IS
Sbjct: 148 CRSAAERDKWIENLQRAVKPNKDNSRRVDNVLKLWIIEARELPPKKRYYCELCLDDMLYARTTSKPRTDTVFWGEHFEFNNLPAVRNLRLHLYKETDKKRRKEKSTYLGLVSIPISSITGRQFVEQWY-PVIQPSV--LAKGGGVGGGKI-----------INASLRLKSRYQTMSILPMELYKEFAEYVTNNYRTLCAVLEPLLSVKSKEEVACALVHILQSTGKAKDFLSDMAMCEVDRFIDREHLIFRENTLATKAIEEYLKLIGHKYLKDALGDFIRALYESEENCEVDPMR----TPPSVLADHQANLRMCCELALCKIVNSHCVFPRELKEVFASWRVRCAERGRED-----IADRLISGSLFLRFLCPAVMSPSLFNLTQEYPDE-QTSRTLTLIAKVMQNLANFSKF-GSKEEYMCFMNEFLEMEWGSMQQFLYEIS 567
BLAST of Disabled 2-interacting protein vs. Ensembl Cavefish
Match: syngap1b (synaptic Ras GTPase activating protein 1b [Source:ZFIN;Acc:ZDB-GENE-100921-2]) HSP 1 Score: 300.442 bits (768), Expect = 1.900e-83 Identity = 178/445 (40.00%), Postives = 254/445 (57.08%), Query Frame = 3
Query: 861 CLSQPEMNEWLTKIKQRINPNYKNSTRHEDLLQIWIQEAKQLIQKKRYYCEIKLDEMLYGRTTIKTVTDTVFWGEEFEFRGLQNINKITICLYKMTDNKKKHERSELVAQIEVPCADLTDSSPCEKWYSPPFQYSNLRLSQSELTNSQKVKLDELLKNAVDIAPMIRIKGRYRPLEILPNKFYDSLSDFLVKQSIPLVESLESHLKVKSKEDFVKILLVILKSKDCHIDFLADLVFIEVSKAED--NLILRGNSIASKAMECYLKMVGEKYLATILKDLINEVIFEEIDCEVDPLRLNNSKENSQIFENQNKLLRLVENVWSKIYHNAHLIPNELKLVFTKIREKLSETKRGSSYSSPMIYQVISSCLFLRFICPAIMSPFLFGLSNEYPDNVSINRTFTLIAKSIQSLANFSQFPQSKETYMEFMQNFINKNSSSMRSFLKLIS 2189
C S E ++W+ +++ + PN NS R +++L++WI EA++L KKRYYCE+ LD+MLY RTT K TDTVFWGE FEF L + + + LYK TD K++ E+S + + +P + +T E+WY P Q S L++ K+ I +R+K RY+ + ILP + Y ++++ L LE L VKSKE+ L+ IL+S DFL+D+ EV + D +LI R N++A+KA+E YLK++G KYL L D I + E +CEVDP+R S + ++Q L E KI ++ + P ELK VF R + +E R + ++IS LFLRF+CPA+MSP LF L+ EYPD +RT TLIAK +Q+LANFS+F SKE YM FM F+ SM+ FL IS
Sbjct: 152 CRSAAERDKWIENLQRAVKPNKDNSRRVDNVLKLWIIEARELPPKKRYYCELCLDDMLYARTTSKPRTDTVFWGEHFEFNNLPAVRNLRLHLYKETDKKRRKEKSTYLGLVSIPISSITGRQFVEQWY-PVIQPSV--LAKGGGVGGGKI-----------INASLRLKSRYQTMSILPMELYKEFAEYVTNNYRTLCAVLEPLLSVKSKEEVACALVHILQSTGKAKDFLSDMAMCEVDRFIDREHLIFRENTLATKAIEEYLKLIGHKYLKDALGDFIRALYESEENCEVDPMR----TPPSVLADHQANLRMCCELALCKIVNSHCVFPRELKEVFASWRVRCAERGRED-----IADRLISGSLFLRFLCPAVMSPSLFNLTQEYPDE-QTSRTLTLIAKVMQNLANFSKF-GSKEEYMCFMNEFLEMEWGSMQQFLYEIS 571
BLAST of Disabled 2-interacting protein vs. Ensembl Cavefish
Match: syngap1b (synaptic Ras GTPase activating protein 1b [Source:ZFIN;Acc:ZDB-GENE-100921-2]) HSP 1 Score: 300.827 bits (769), Expect = 2.054e-83 Identity = 178/445 (40.00%), Postives = 254/445 (57.08%), Query Frame = 3
Query: 861 CLSQPEMNEWLTKIKQRINPNYKNSTRHEDLLQIWIQEAKQLIQKKRYYCEIKLDEMLYGRTTIKTVTDTVFWGEEFEFRGLQNINKITICLYKMTDNKKKHERSELVAQIEVPCADLTDSSPCEKWYSPPFQYSNLRLSQSELTNSQKVKLDELLKNAVDIAPMIRIKGRYRPLEILPNKFYDSLSDFLVKQSIPLVESLESHLKVKSKEDFVKILLVILKSKDCHIDFLADLVFIEVSKAED--NLILRGNSIASKAMECYLKMVGEKYLATILKDLINEVIFEEIDCEVDPLRLNNSKENSQIFENQNKLLRLVENVWSKIYHNAHLIPNELKLVFTKIREKLSETKRGSSYSSPMIYQVISSCLFLRFICPAIMSPFLFGLSNEYPDNVSINRTFTLIAKSIQSLANFSQFPQSKETYMEFMQNFINKNSSSMRSFLKLIS 2189
C S E ++W+ +++ + PN NS R +++L++WI EA++L KKRYYCE+ LD+MLY RTT K TDTVFWGE FEF L + + + LYK TD K++ E+S + + +P + +T E+WY P Q S L++ K+ I +R+K RY+ + ILP + Y ++++ L LE L VKSKE+ L+ IL+S DFL+D+ EV + D +LI R N++A+KA+E YLK++G KYL L D I + E +CEVDP+R S + ++Q L E KI ++ + P ELK VF R + +E R + ++IS LFLRF+CPA+MSP LF L+ EYPD +RT TLIAK +Q+LANFS+F SKE YM FM F+ SM+ FL IS
Sbjct: 221 CRSAAERDKWIENLQRAVKPNKDNSRRVDNVLKLWIIEARELPPKKRYYCELCLDDMLYARTTSKPRTDTVFWGEHFEFNNLPAVRNLRLHLYKETDKKRRKEKSTYLGLVSIPISSITGRQFVEQWY-PVIQPSV--LAKGGGVGGGKI-----------INASLRLKSRYQTMSILPMELYKEFAEYVTNNYRTLCAVLEPLLSVKSKEEVACALVHILQSTGKAKDFLSDMAMCEVDRFIDREHLIFRENTLATKAIEEYLKLIGHKYLKDALGDFIRALYESEENCEVDPMR----TPPSVLADHQANLRMCCELALCKIVNSHCVFPRELKEVFASWRVRCAERGRED-----IADRLISGSLFLRFLCPAVMSPSLFNLTQEYPDE-QTSRTLTLIAKVMQNLANFSKF-GSKEEYMCFMNEFLEMEWGSMQQFLYEIS 640
BLAST of Disabled 2-interacting protein vs. Ensembl Cavefish
Match: syngap1b (synaptic Ras GTPase activating protein 1b [Source:ZFIN;Acc:ZDB-GENE-100921-2]) HSP 1 Score: 300.442 bits (768), Expect = 2.105e-83 Identity = 178/445 (40.00%), Postives = 254/445 (57.08%), Query Frame = 3
Query: 861 CLSQPEMNEWLTKIKQRINPNYKNSTRHEDLLQIWIQEAKQLIQKKRYYCEIKLDEMLYGRTTIKTVTDTVFWGEEFEFRGLQNINKITICLYKMTDNKKKHERSELVAQIEVPCADLTDSSPCEKWYSPPFQYSNLRLSQSELTNSQKVKLDELLKNAVDIAPMIRIKGRYRPLEILPNKFYDSLSDFLVKQSIPLVESLESHLKVKSKEDFVKILLVILKSKDCHIDFLADLVFIEVSKAED--NLILRGNSIASKAMECYLKMVGEKYLATILKDLINEVIFEEIDCEVDPLRLNNSKENSQIFENQNKLLRLVENVWSKIYHNAHLIPNELKLVFTKIREKLSETKRGSSYSSPMIYQVISSCLFLRFICPAIMSPFLFGLSNEYPDNVSINRTFTLIAKSIQSLANFSQFPQSKETYMEFMQNFINKNSSSMRSFLKLIS 2189
C S E ++W+ +++ + PN NS R +++L++WI EA++L KKRYYCE+ LD+MLY RTT K TDTVFWGE FEF L + + + LYK TD K++ E+S + + +P + +T E+WY P Q S L++ K+ I +R+K RY+ + ILP + Y ++++ L LE L VKSKE+ L+ IL+S DFL+D+ EV + D +LI R N++A+KA+E YLK++G KYL L D I + E +CEVDP+R S + ++Q L E KI ++ + P ELK VF R + +E R + ++IS LFLRF+CPA+MSP LF L+ EYPD +RT TLIAK +Q+LANFS+F SKE YM FM F+ SM+ FL IS
Sbjct: 222 CRSAAERDKWIENLQRAVKPNKDNSRRVDNVLKLWIIEARELPPKKRYYCELCLDDMLYARTTSKPRTDTVFWGEHFEFNNLPAVRNLRLHLYKETDKKRRKEKSTYLGLVSIPISSITGRQFVEQWY-PVIQPSV--LAKGGGVGGGKI-----------INASLRLKSRYQTMSILPMELYKEFAEYVTNNYRTLCAVLEPLLSVKSKEEVACALVHILQSTGKAKDFLSDMAMCEVDRFIDREHLIFRENTLATKAIEEYLKLIGHKYLKDALGDFIRALYESEENCEVDPMR----TPPSVLADHQANLRMCCELALCKIVNSHCVFPRELKEVFASWRVRCAERGRED-----IADRLISGSLFLRFLCPAVMSPSLFNLTQEYPDE-QTSRTLTLIAKVMQNLANFSKF-GSKEEYMCFMNEFLEMEWGSMQQFLYEIS 641
BLAST of Disabled 2-interacting protein vs. Ensembl Cavefish
Match: syngap1b (synaptic Ras GTPase activating protein 1b [Source:ZFIN;Acc:ZDB-GENE-100921-2]) HSP 1 Score: 301.212 bits (770), Expect = 2.112e-83 Identity = 178/445 (40.00%), Postives = 254/445 (57.08%), Query Frame = 3
Query: 861 CLSQPEMNEWLTKIKQRINPNYKNSTRHEDLLQIWIQEAKQLIQKKRYYCEIKLDEMLYGRTTIKTVTDTVFWGEEFEFRGLQNINKITICLYKMTDNKKKHERSELVAQIEVPCADLTDSSPCEKWYSPPFQYSNLRLSQSELTNSQKVKLDELLKNAVDIAPMIRIKGRYRPLEILPNKFYDSLSDFLVKQSIPLVESLESHLKVKSKEDFVKILLVILKSKDCHIDFLADLVFIEVSKAED--NLILRGNSIASKAMECYLKMVGEKYLATILKDLINEVIFEEIDCEVDPLRLNNSKENSQIFENQNKLLRLVENVWSKIYHNAHLIPNELKLVFTKIREKLSETKRGSSYSSPMIYQVISSCLFLRFICPAIMSPFLFGLSNEYPDNVSINRTFTLIAKSIQSLANFSQFPQSKETYMEFMQNFINKNSSSMRSFLKLIS 2189
C S E ++W+ +++ + PN NS R +++L++WI EA++L KKRYYCE+ LD+MLY RTT K TDTVFWGE FEF L + + + LYK TD K++ E+S + + +P + +T E+WY P Q S L++ K+ I +R+K RY+ + ILP + Y ++++ L LE L VKSKE+ L+ IL+S DFL+D+ EV + D +LI R N++A+KA+E YLK++G KYL L D I + E +CEVDP+R S + ++Q L E KI ++ + P ELK VF R + +E R + ++IS LFLRF+CPA+MSP LF L+ EYPD +RT TLIAK +Q+LANFS+F SKE YM FM F+ SM+ FL IS
Sbjct: 222 CRSAAERDKWIENLQRAVKPNKDNSRRVDNVLKLWIIEARELPPKKRYYCELCLDDMLYARTTSKPRTDTVFWGEHFEFNNLPAVRNLRLHLYKETDKKRRKEKSTYLGLVSIPISSITGRQFVEQWY-PVIQPSV--LAKGGGVGGGKI-----------INASLRLKSRYQTMSILPMELYKEFAEYVTNNYRTLCAVLEPLLSVKSKEEVACALVHILQSTGKAKDFLSDMAMCEVDRFIDREHLIFRENTLATKAIEEYLKLIGHKYLKDALGDFIRALYESEENCEVDPMR----TPPSVLADHQANLRMCCELALCKIVNSHCVFPRELKEVFASWRVRCAERGRED-----IADRLISGSLFLRFLCPAVMSPSLFNLTQEYPDE-QTSRTLTLIAKVMQNLANFSKF-GSKEEYMCFMNEFLEMEWGSMQQFLYEIS 641
BLAST of Disabled 2-interacting protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000945.1 (pep scaffold:Pmarinus_7.0:GL477254:323984:383899:1 gene:ENSPMAG00000000852.1 transcript:ENSPMAT00000000945.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 252.292 bits (643), Expect = 6.377e-69 Identity = 171/443 (38.60%), Postives = 250/443 (56.43%), Query Frame = 3
Query: 861 CLSQPEMNEWLTKIKQRINPNYKNSTRHEDLLQIWIQEAKQLIQKKRYYCEIKLDEMLYGRTTIKTVTDTVFWGEEFEFRGLQNINKITICLYKMTDNKKKHERSELVAQIEVPCADLTDSSP-CEKWYSPPFQYSNLRLSQSELTNSQKVKLDELLKNAVDIAPMIRIKGRYRPLEILPNKFYDSLSDFLVKQSIPLVESLESHLKVKSKEDFVKILLVILKSKDCHIDFLADLVFIEVSKAEDN--LILRGNSIASKAMECYLKMVGEKYLATILKDLINEVIFE-EIDCEVDPLRLNNSKENSQIFENQNKLLRLVENVWSKIYHNAHLIPNELKLVFTKIREKLSETKRGSSYSSPMIYQVISSCLFLRFICPAIMSPFLFGLSNEYPDNVSINRTFTLIAKSIQSLANFSQFPQSKETYMEFMQNFINKNSSSMRSFL 2177
C S E ++W+ +++ + PN N R E+ L++WI EAK+L KK+Y+CEI LD+ LY RT K D +FWGE FEF L + I + LYK TD KKK E+S V + + T EKWY P N K AV P +RIK R++ L ILP + Y ++FL +PL LE L VKSKE+ + L+ L + +FLA+LV EV++ +N L+ R N++A+KA+E YLKMVG+ YL L+ +++ + +CEV+ + + ++++ +++N L E + KI + + P EL+ VF+ R +L E + + S ++IS+ LFLRF+CPAIMSP LFGLS EYPD + RT TLIAK +Q+LANF++F +KE YM FM F+ + M+ FL
Sbjct: 16 CRSAAEQDKWMENLRRIVQPNKDNIQRVENDLKVWIIEAKELPAKKKYFCEICLDDTLYARTASKAKVDNLFWGEHFEFSNLPAVKHIMVHLYKDTDKKKKKEKSSYVGLVNISVEGGTSGRQFVEKWY--PLSTPNPGKG----------------KGAV---PTVRIKWRHQQLSILPMERYKEFAEFLSASCLPLCLLLEPVLGVKSKEELARALVRFLHTTGRVKEFLAELVIAEVTRCSENEHLLFRENTLATKAIEEYLKMVGQWYLHDALEGEFVRALYDSDENCEVELSKCS----SAELADHRNNLRMCCELAFCKILSSCCVFPAELRDVFSSWR-RLCEARGRAEISE----RLISASLFLRFLCPAIMSPSLFGLSQEYPDERTA-RTLTLIAKVVQNLANFTKF-GNKEDYMTFMNGFLEQEWGRMKQFL 426
BLAST of Disabled 2-interacting protein vs. Ensembl Yeast
Match: BUD2 (GTPase activating factor for Rsr1p/Bud1p; plays a role in spindle position checkpoint distinct from its role in bud site selection; required for both axial and bipolar budding patterns; mutants exhibit random budding in all cell types; contains two PH-like domains [Source:SGD;Acc:S000001575]) HSP 1 Score: 106.686 bits (265), Expect = 1.141e-23 Identity = 103/407 (25.31%), Postives = 188/407 (46.19%), Query Frame = 3
Query: 1035 YGRTTIKTVTDTVFWGEEFEFRGLQNINKITICLYKMTDNKKKHERSELVAQIEVPCADLTDSS-------PCEKWYSPPFQYSNLRLSQSE-----LTNSQKVKLDELLKNAVDIAPMIRIKGRYRPLEILPNKFYDSLSDF-----LVKQSIPLVESLESHLKVKS------KEDFVKILLVILKSKDCHIDFLADLVFIEVSKAEDNLILRGNSIASKAMECYLKMVGEKYLATILKDLINEVIFEEIDCEVDPLRL---NNSKENSQIFENQNKLLRLVENVWSKIYHNAHLIPNELKLVFTKIREKLSETKRGSSYSSPMIYQVISSCLFLRFICPAIMSPFLFGLSNEYPDNVSINRTFTLIAKSIQSLANFSQFPQSKETYMEFMQNFINKNSSSMRSFL 2177
+ RT++ + + FW EEF+F L + + + ++ + +R L+ +I++ + D+ P + FQ + + S L ++ VKL++LL NA L ++ N Y S S L + SI ++ +S +++ ++ KI + + ++D SK N + RGNSI +K++E Y VG +YL+ L ++ E+I CE+DP R+ + K+ I +N +L V +W ++Y ++ +P E++ V R+KL + +I IS LFLRF CP I++P LF ++ N + R TLI+K + +L+ +QF +KE ++ M NFI+K + + ++
Sbjct: 372 WARTSMVSNSSNPFWREEFQFNELLRLTNSYLEIKQLFHDLNNKKRLRLIGKIKITQEIINDTRYNKETRLPIMDVDNKNFQIGTICIKISSNLNFILPSTNFVKLEKLLMNA--------------NLSMVSNLIYKSSSSMENDNKLTQTSIIFLDIFQSLSRIEEWFHVLIDKELAKIDGTVSRINQKNLD----------SKHVFNSLFRGNSILTKSIEQYFFRVGNEYLSKALSAILKEIIESNKSCELDPARVKEKDEVKKRKIIADNYKRLYSWVTKIWKRLYATSNDLPIEIRNVLKIFRQKLEIICIDDTLQ--IILNGISGLLFLRFFCPVILNPKLFKYVSQNL-NETARRNLTLISKVLLNLSTLTQFA-NKEPWLMKMNNFIDKRHNDLLDYI 750
BLAST of Disabled 2-interacting protein vs. Ensembl Yeast
Match: IRA1 (GTPase-activating protein; negatively regulates RAS by converting it from GTP- to the GDP-bound inactive form, required for reducing cAMP levels under nutrient limiting conditions, mediates membrane association of adenylate cyclase; mutations cause catalase T deficiency, defective glycogen synthesis and defective trehalose accumulation; IRA1 has a paralog, IRA2, that arose from the whole genome duplication; defects in human homolog NF1 are associated with neurofibromatosis [Source:SGD;Acc:S000000344]) HSP 1 Score: 51.9878 bits (123), Expect = 8.545e-7 Identity = 52/177 (29.38%), Postives = 84/177 (47.46%), Query Frame = 3
Query: 1584 AEDNLILRGNSIASKAMECYLKMVGEKYLATILKDLINEVIFEEIDCEVDPLRLN--NSKENSQIFENQNKLLRLVENVWSKIYHNAHLIPNELKLVFTKIREKLSETKRGSSYSSP-MIYQVISSCLFLRFICPAIMSPFLFGLSNEYPDNVSI------NRTFTLIAKSIQSLAN 2087
A + ILR NS A++A+ Y + G KYL L+ ++ ++ + E+D ++ NS++ +FE + RL++ + S I P EL + I +S + P Y + S +FLRFI PA++SP +N+ I + F +AK IQSLAN
Sbjct: 1743 ARSDDILRRNSCATRALSLYTRSRGNKYLIKTLRPVLQGIVDNKESFEIDKMKPGSENSEKMLDLFEKY--MTRLIDAITSSIDD----FPIELVDICKTIYN-------AASVNFPEYAYIAVGSFVFLRFIGPALVSP--------DSENIIIVTHAHDRKPFITLAKVIQSLAN 1898
BLAST of Disabled 2-interacting protein vs. Ensembl Nematostella
Match: EDO35799 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SKG2]) HSP 1 Score: 282.722 bits (722), Expect = 5.705e-79 Identity = 169/448 (37.72%), Postives = 244/448 (54.46%), Query Frame = 3
Query: 861 CLSQPEMNEWLTKIKQRINPNYKNSTRHEDLLQIWIQEAKQLIQ--KKRYYCEIKLDEMLYGRTTIKTVTDTVFWGEEFEFRGLQNINKITICLYKMTDNKKKHERSELVAQIEVPCADLTDSSPCEKWYSPPFQYSNLRLSQSELTNSQKVKLDELLKNAVDIAPMIRIKGRYRPLEILPNKFYDSLSDFLVKQSIPLVESLESHLKVKSKEDFVKILLVILKSKDCHIDFLADLVFIEVSK---AEDNLILRGNSIASKAMECYLKMVGEKYLATILKDLINEVIFEEIDCEVDPLRLNNSKENSQIFENQNKLLRLVENVWSKIYHNAHLIPNELKLVFTKIREKLSETKRGSSYSSPMIYQVISSCLFLRFICPAIMSPFLFGLSNEYPDNVSINRTFTLIAKSIQSLANFSQFPQSKETYMEFMQNFINKNSSSMRSFLKLIS 2189
C S E+N+W+ IK+ I P R + L +W+ EAK + KKRY+CE+ LD+MLY RTT KT DT+FWGE F F L +++ IT+ +YK + K K E+ +LV + +P DL S EKW+ +D K D + IR+K +Y+ + ILP Y+ + +L + L +LES + K K++ ++L +L+ +FL D+V EV++ A++NL+ RGNS A+KAM+ Y+KMVGE + L D + V DCEVDP + N I NQ L E W+ I ++ + P +L+ F + R+ R + S + ++IS+ +FLRF+CPAIMSP LF L EYP N I RT TLIAK IQ+LANF++F KE YM FM +F+ MR F+ IS
Sbjct: 36 CRSAQELNKWVNSIKKSIQPARDQQNRMDISLSVWVCEAKGAMTTPKKRYFCELLLDKMLYARTTSKTKVDTLFWGENFSFDDLLDLSTITVNIYKDLEAKNKKEKRKLVGTVNIPVRDLDSSQEVEKWFP----------------------VDMTTKGNAD-SGSIRLKIKYQKIHILPLTTYNEMLSYLSNNYMHLCGTLESAVSSKVKDEIAGVILRVLQPVGKAQEFLVDIVMDEVNRLGSADENLVFRGNSFATKAMDTYMKMVGE---SETLGDFVQSVYAMSEDCEVDPAK----SVNGSIQSNQENLKAFAEKAWNHILCSSCIFPCDLQDTFHEFRQ------RSINGSRDLSNKLISASIFLRFLCPAIMSPSLFHLVQEYP-NERILRTLTLIAKVIQNLANFTKF-GGKEDYMGFMNDFVQNEFDKMREFVATIS 445
BLAST of Disabled 2-interacting protein vs. Ensembl Nematostella
Match: EDO36190 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SJB4]) HSP 1 Score: 127.487 bits (319), Expect = 5.154e-30 Identity = 122/455 (26.81%), Postives = 215/455 (47.25%), Query Frame = 3
Query: 861 CLSQPEM-NEWLTKIKQRINPNYKN------STRHEDLLQIWIQEAKQLIQKK--RYYCEIKLDEMLYGRTTIKTV-TDTVFWGEEFEFRGL-QNINKITICLYKMTDNKKKHERSELVAQIEVPCADLTDSSPCEKWYSPPFQYSNLRLSQSELTNSQKVKLDELLKNAVDIAPMIRIKGRYRPLEILPNKFYDSLSDFLVKQSIPLVESLESHLKVKSKEDFVKILLVILKSKDCHIDFLADLVFIEVSKAEDNLIL-RGNSIASKAMECYLKMVGEKYLATILKDLINEVIFEEIDCEVDPLRLNNSKENSQIFENQNKLLRLVENVWSKIYHNAHLIPNELKLVFTKIREKLSETKRGSSYSSPMIYQVISSCLFLRFICPAIMSPFLFGLSNEYPDNVSINRTFTLIAKSIQSLANFSQFPQSKETYMEFMQNFINKNSSSMRSFLKLIS 2189
C P++ NEW+ + Q+I K+ + L++ + EA +L K YC + L+E+ RT KT T W EEF+F L +++ T+ LY NK + L+ + VP L + WY P ++ ++E+ N +RI+ ++ I+P + Y++L + L+ + + V +L K + LL I + + I L + E+ K ++ L RG S+A+ M+ Y+KMV YL +KD+I +++ + CE++P ++ ++ + N +LL + I+ +A P L+ +F +++ + K + + + +V+S LFLR CPAIM+P L +E P + + RT TL+AK +Q LAN +F +KE+ M + F+ KN M SF+ +S
Sbjct: 201 CADTPDLANEWMDAV-QKICGKSKSLDVIDVDVKQLRSLELNVIEAHKLPLNKVSHPYCMVSLNEVKTCRT--KTFEGQTPLWNEEFKFNDLPSDVSSFTLSLY----NKSWRTKDVLIGHVLVPLNKLPKGQTVDDWY--PLAAASH--GKAEVGN-------------------VRIRVKFTHEIIMPVEEYEALKEILLDEDLVAVTALGQ--VCKDRVVLASTLLKIFRHEKQEIFLLKTMNAREIEKQDEQATLFRGASLATSLMDQYMKMVAIPYLQHTIKDVILKILECKQSCELNPAKM---EKGADTVVNLKQLLEFLFEAIDAIFTSAEECPKTLRYLFGCLQQNV---KDKWADNQTVRTRVVSGFLFLRLFCPAIMNPKTCNLMSELP-SATAARTLTLVAKCLQKLANLVEF-GAKESCMTPVNPFMQKNRERMVSFMDELS 615
BLAST of Disabled 2-interacting protein vs. Ensembl Nematostella
Match: EDO43446 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RYE3]) HSP 1 Score: 120.168 bits (300), Expect = 1.740e-27 Identity = 89/288 (30.90%), Postives = 152/288 (52.78%), Query Frame = 3
Query: 1356 IRIKGRYRPLEILPNKFYDSLSDFLVK-QSIPLVESLESHLK---VKSKEDFVKILLVILKSKDCHIDFLADLVFIEVSKAED-NLILRGNSIASKAMECYLKMVGEKYLATILKDLINEVIFEEIDCEVDPLRLNNSKENSQIFENQNKLLRLVENVWSKIYHNAHLIPNELKLVFTKIREKLSETKRGSSYSSPMIYQVISSCLFLRFICPAIMSPFLFGLSNEYPDNVSINRTFTLIAKSIQSLANFSQ---FPQSKETYMEFMQNFI--NKNSSSMRSFLKLIS 2189
+R+K Y + P+ +Y+ L + +++ + V + +++ VK K + L+ + + +DF+ +V EV+ D N + RGNS+ +KA++ ++K G +YL +K L++E+ E CE+DP RL ++ + +N L V + + I +A P + VF IRE S +R S + Y +S +FLRF PAI++P LF + NE+PD + + RT TL +K+IQSL N Q KE YME ++ I + ++++ FL IS
Sbjct: 276 LRLKVCYTEDYVFPSSYYEPLREAILEIEGHKDVTTTPAYILSEIVKDKLTAARALVRVFTHHNKVVDFIKAVVDHEVNTTADCNTLFRGNSLGTKAIDEFMKHAGMQYLHETIKTLVDEIYEERKCCEIDPSRL---RDGDSLPQNLANLQGYVNKLCAAITCSAMACPTAMSKVFVTIRE--SAVQRFSD-EPDVRYTAVSGFVFLRFFAPAILNPKLFQMRNEHPDPL-VARTLTLASKAIQSLGNLVSSVICGQVKEPYMESLKAMILDQDHITAVKRFLDAIS 556
BLAST of Disabled 2-interacting protein vs. Ensembl Nematostella
Match: EDO40933 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S5U4]) HSP 1 Score: 57.7658 bits (138), Expect = 3.020e-8 Identity = 60/233 (25.75%), Postives = 115/233 (49.36%), Query Frame = 3
Query: 1572 EVSKAED-NLILRGNSIASKAMECYLKMV-GEKYLATILKDLINEVIFEE-IDCEVDPLR----------------LNNSKENSQIFENQNKLLRLVENVWSK----IYHNAHLIPNELKLVFTKIREKLSETKRGSSYSSPMIYQVISSCLFLRFICPAIMSPFLFGLSNEYPDNVSINRTFTLIAKSIQSLAN----FSQFPQSKETYMEFMQNFINKNSSSMRSFLKLIS 2189
E +++E+ N +LR N+ S+ M Y + G++YL L++ +N+++ +E + E++P++ L + ++ ++ ++ ++++ S I + +P ++ + I+E E + + I +I LRFI PAI++P + L N+ P ++ R TLIAK +QS+AN S F KE YM+ +Q F + M+SFL +S
Sbjct: 147 EFAESENFNSLLRANTAISRMMTTYTRRGPGQEYLKCTLEEPLNDLMSQEDLVLEINPIKVYIELYGHPMDESSLTLERAMDDPEVMFRTKLRIKKLQDISSLFLGIIISSLSQVPYGIQWLCRAIKELAME--KFPEATPEQINAMIGGFFLLRFINPAIVTPTAYMLVNKQP-TYTMRRNLTLIAKILQSMANKNVVSSHF---KEEYMQPLQPFAINHVDLMQSFLSDLS 373
BLAST of Disabled 2-interacting protein vs. Ensembl Medaka
Match: ENSORLT00000022035.2 (disabled homolog 2-interacting protein-like [Source:NCBI gene;Acc:101175325]) HSP 1 Score: 311.612 bits (797), Expect = 2.753e-88 Identity = 184/491 (37.47%), Postives = 273/491 (55.60%), Query Frame = 3
Query: 861 CLSQPEMNEWLTKIKQRINPNYKNSTRHEDLLQIWIQEAKQLIQKKRYYCEIKLDEMLYGRTTIKTVTDTVFWGEEFEFRGLQNINKITICLYKMTDNKKKHERSELVAQIEVPCADLTDSSPCEKWYSPPFQYSNLRLSQSELTNSQKVKLDELLKNAVDIAPMIRIKGRYRPLEILPNKFYDSLSDFLVKQSIPLVESLESHLKVKSKEDFVKILLVILKSKDCHIDFLADLVFIEVSKAEDN--LILRGNSIASKAMECYLKMVGEKYLATILKDLINEVIFEEIDCEVDPLRLNNSKENSQIFENQNKLLRLVENVWSKIYHNAHLIPNELKLVFTKIREKLSETKRGSSYSSPMIYQ-VISSCLFLRFICPAIMSPFLFGLSNEYPDNVSINRTFTLIAKSIQSLANFSQFPQSKETYMEFMQNFINKNSSSMRSFLKLISLNKSNGAKSMESQDVLYLLLETDKINYSPTKDDRYIDIGYHLAEL 2324
C S E ++W+ +++ ++PN NS R E++L +W+ EAK L KKRY+CE+ LD+ LY RT+ K TD +FWGE F+F L ++N IT+ LYK TD K+K ++S V + +P + +T EKWYS V ++ I P +R+K RY+ + ILP + Y ++++ + L +LE+ + +++KE+ L+ IL S DFL DL+ EV + DN LI R N++A+K++E YLK++G+KYL L + I + + +CEVDP R + S + E+Q L E + KI + + P ELK VF R++ S R P I + +IS+ LFLRF+CPA+MSP LF L EYPD + RT TLIAK IQ+LANFS+F +KE YM FM +F+ + SSM+ FL+ IS D +N++ D YID+G L+ L
Sbjct: 58 CRSAAERDKWMENLRRAVHPNKDNSRRLENVLTVWVIEAKDLPAKKRYFCELCLDDSLYARTSCKLKTDNIFWGEHFDFCSLPSVNSITLHLYKDTDRKRKKDKSSYVGLVNIPVSTVTGRQLVEKWYS--------------------VSTPSTIRGKSSI-PNVRVKARYQSIIILPMEQYKEFAEYISSNYLLLCSTLEASISLRAKEELAAALVHILHSTGKAKDFLTDLMMSEVDRCRDNDQLIFRENTLATKSIEEYLKLIGQKYLQDALGEFIKALYESDENCEVDPARCS----TSDLAEHQANLRMCCELAFCKILDSYRVFPRELKEVFASWRQECSNRGR------PDISERLISASLFLRFLCPAVMSPSLFDLMQEYPDERTA-RTLTLIAKVIQNLANFSKF-GTKEEYMLFMNDFVERQWSSMQRFLQEIS--------------------NPDGLNHTAGFDG-YIDLGRELSSL 494
BLAST of Disabled 2-interacting protein vs. Ensembl Medaka
Match: syngap1b (ras/Rap GTPase-activating protein SynGAP [Source:NCBI gene;Acc:101163690]) HSP 1 Score: 300.056 bits (767), Expect = 3.598e-83 Identity = 192/515 (37.28%), Postives = 279/515 (54.17%), Query Frame = 3
Query: 861 CLSQPEMNEWLTKIKQRINPNYKNSTRHEDLLQIWIQEAKQLIQKKRYYCEIKLDEMLYGRTTIKTVTDTVFWGEEFEFRGLQNINKITICLYKMTDNKKKHERSELVAQIEVPCADLTDSSPCEKWYSPPFQYSNLRLSQSELTNSQKVKLDELLKNAVDIAPMIRIKGRYRPLEILPNKFYDSLSDFLVKQSIPLVESLESHLKVKSKEDFVKILLVILKSKDCHIDFLADLVFIEVSKAED--NLILRGNSIASKAMECYLKMVGEKYLATILKDLINEVIFEEIDCEVDPLRLNNSKENSQIFENQNKLLRL-VENVWSKIYHNAHLIPNELKLVFTKIREKLSETKRGSSYSSPMIYQVISSCLFLRFICPAIMSPFLFGLSNEYPDNVSINRTFTLIAKSIQSLANFSQFPQSKETYMEFMQNFINKNSSSMRSFLKLIS-LNKSNGAKSMESQDVLYLLLETDKINYSPTKDDRYIDIGYHLA-------ELMFQLN----IHLKDIP 2360
C S E ++W+ +++ + PN NS R +++L++WI EA++L KKRYYCE+ LD+MLY RTT K TDTVFWGE FEF L + + + LYK TD K++ E+S + + +P + +T E+WY P Q S LT V +++ + +R+K R++ + ILP + Y ++++ L LE L VKSKE+ L+ IL+S DFL+D+ EV + D +LI R N++A+KA+E YLK++G KYL + + I + E +CEVDP+R++ S I + LR+ E KI ++ + P ELK VF R + +E R + ++IS LFLRF+CPAIMSP LF L+ EYPD +RT TLIAK +Q+LANFS+F SKE YM FM F+ SM+ FL IS L+ + A E YID+G L+ E+M QL+ I L +P
Sbjct: 220 CRSAAERDKWIENLQRAVKPNKDNSRRVDNVLKLWIIEARELPAKKRYYCELCLDDMLYARTTSKPRTDTVFWGEHFEFNNLPAVRNLRLHLYKETDKKRRKEKSTYLGLVSIPISSITGRQFVEQWY-PVIQ-------PSVLTKGAGVGGGKIINAS------LRLKSRFQTMNILPMELYKEFAEYVTNNYRTLCAVLEPVLSVKSKEEVACALVHILQSTGKAKDFLSDMAMCEVDRFIDREHLIFRENTLATKAIEEYLKLIGHKYLKDAIGEFIRALYESEENCEVDPMRISPS-----ILPDHQANLRMCCELALCKIVNSHCVFPRELKEVFASWRVRCAERGRED-----IADRLISGSLFLRFLCPAIMSPSLFNLTQEYPDE-QTSRTLTLIAKVVQNLANFSKF-GSKEEYMCFMNEFLEMEWGSMQQFLYEISNLDSVSNAGGFEG----------------------YIDLGRELSILHSLLWEVMAQLSKDAIIKLGPLP 686
BLAST of Disabled 2-interacting protein vs. Ensembl Medaka
Match: ENSORLT00000037743.1 (ras/Rap GTPase-activating protein SynGAP [Source:NCBI gene;Acc:101160492]) HSP 1 Score: 296.975 bits (759), Expect = 1.271e-82 Identity = 180/458 (39.30%), Postives = 257/458 (56.11%), Query Frame = 3
Query: 861 CLSQPEMNEWLTKIKQRINPNYKNSTRHEDLLQIWIQEAKQLIQKKRYYCEIKLDEMLYGRTTIKTVTDTVFWGEEFEFRGLQNINKITICLYKMTDNKKKHERSELVAQIEVPCADLTDSSPCEKWYSPPFQYSNLRLSQSELTNSQKVKLDELLKNAVDIAPMIRIKGRYRPLEILPNKFYDSLSDFLVKQSIPLVESLESHLKVKSKEDFVKILLVILKSKDCHIDFLADLVFIEVSKAED--NLILRGNSIASKAMECYLKMVGEKYLATILKDLINEVIFEEIDCEVDPLRLNNSKENSQIFENQNKLLRLVENVWSKIYHNAHLIPNELKLVFTKIREKLSETKRGSSYSSPMIYQVISSCLFLRFICPAIMSPFLFGLSNEYPDNVSINRTFTLIAKSIQSLANFSQFPQSKETYMEFMQNFINKNSSSMRSFLKLIS-LNKSNGAKSMES 2225
C S E ++W+ +++ + PN NS R +++L++WI EA+ L KKRYYCE+ LD+MLY RTT K TDTVFWGE FEF L I + + LYK TD K++ E+S + + +P + +T E+WY P Q S L++ S KV I +RIK RY+ + ILP + Y ++++ L LE L VKSKE+ L+ IL+S +FL+D+ E + D +LI R N++A+KA+E YLK++G +YL + D I + E +CEVDP+R+ S + ++Q L E + KI ++ + P ELK VF R + +E R S +ISS LFLRF+CPAIMSP LF L EYP + +RT TLIA+ +Q+LA+FS+F KE YM FM F+ SM+ FL IS L+ A E
Sbjct: 83 CRSASERDKWIENLQRAVKPNKDNSRRVDNVLKLWIIEARDLPAKKRYYCELCLDDMLYARTTSKPRTDTVFWGEHFEFNNLPTIRSLRLHLYKETDKKRRKEKSTYIGLVSIPISSITGRQFVEQWY-PVIQSSV--LAKGGGVGSTKV-----------INASLRIKSRYQTMNILPMELYKEFAEYITNNYRTLCAVLEPLLSVKSKEEVAFALVHILQSTGKTKEFLSDMAMCEADRFMDREHLIFRENTLATKAVEEYLKLIGHRYLKEAIGDFIRALYESEENCEVDPMRV----PPSVLADHQANLRMCCELLLCKIINSLCIFPRELKEVFASWRARCAERGREDLADS-----LISSSLFLRFMCPAIMSPSLFSLMQEYPAERT-SRTLTLIARVMQNLASFSKF-GPKEEYMYFMNEFLEMEWGSMQQFLYEISNLDTGGNAGGFEG 515
BLAST of Disabled 2-interacting protein vs. Ensembl Medaka
Match: ENSORLT00000003989.2 (ras/Rap GTPase-activating protein SynGAP [Source:NCBI gene;Acc:101160492]) HSP 1 Score: 297.36 bits (760), Expect = 1.645e-82 Identity = 189/503 (37.57%), Postives = 270/503 (53.68%), Query Frame = 3
Query: 861 CLSQPEMNEWLTKIKQRINPNYKNSTRHEDLLQIWIQEAKQLIQKKRYYCEIKLDEMLYGRTTIKTVTDTVFWGEEFEFRGLQNINKITICLYKMTDNKKKHERSELVAQIEVPCADLTDSSPCEKWYSPPFQYSNLRLSQSELTNSQKVKLDELLKNAVDIAPMIRIKGRYRPLEILPNKFYDSLSDFLVKQSIPLVESLESHLKVKSKEDFVKILLVILKSKDCHIDFLADLVFIEVSKAED--NLILRGNSIASKAMECYLKMVGEKYLATILKDLINEVIFEEIDCEVDPLRLNNSKENSQIFENQNKLLRLVENVWSKIYHNAHLIPNELKLVFTKIREKLSETKRGSSYSSPMIYQVISSCLFLRFICPAIMSPFLFGLSNEYPDNVSINRTFTLIAKSIQSLANFSQFPQSKETYMEFMQNFINKNSSSMRSFLKLIS-LNKSNGAKSMESQDVLYLLLETDKINYSPTKDDRYIDIGYHLA-------ELMFQLN 2339
C S E ++W+ +++ + PN NS R +++L++WI EA+ L KKRYYCE+ LD+MLY RTT K TDTVFWGE FEF L I + + LYK TD K++ E+S + + +P + +T E+WY P Q S L++ S KV I +RIK RY+ + ILP + Y ++++ L LE L VKSKE+ L+ IL+S +FL+D+ E + D +LI R N++A+KA+E YLK++G +YL + D I + E +CEVDP+R+ S + ++Q L E + KI ++ + P ELK VF R + +E R S +ISS LFLRF+CPAIMSP LF L EYP + +RT TLIA+ +Q+LA+FS+F KE YM FM F+ SM+ FL IS L+ A E YID+G L+ E+M QL+
Sbjct: 167 CRSASERDKWIENLQRAVKPNKDNSRRVDNVLKLWIIEARDLPAKKRYYCELCLDDMLYARTTSKPRTDTVFWGEHFEFNNLPTIRSLRLHLYKETDKKRRKEKSTYIGLVSIPISSITGRQFVEQWY-PVIQSSV--LAKGGGVGSTKV-----------INASLRIKSRYQTMNILPMELYKEFAEYITNNYRTLCAVLEPLLSVKSKEEVAFALVHILQSTGKTKEFLSDMAMCEADRFMDREHLIFRENTLATKAVEEYLKLIGHRYLKEAIGDFIRALYESEENCEVDPMRV----PPSVLADHQANLRMCCELLLCKIINSLCIFPRELKEVFASWRARCAERGREDLADS-----LISSSLFLRFMCPAIMSPSLFSLMQEYPAERT-SRTLTLIARVMQNLASFSKF-GPKEEYMYFMNEFLEMEWGSMQQFLYEISNLDTGGNAGGFEG----------------------YIDLGRELSMLHSLLWEVMGQLS 622
BLAST of Disabled 2-interacting protein vs. Ensembl Medaka
Match: ENSORLT00000039029.1 (ras/Rap GTPase-activating protein SynGAP [Source:NCBI gene;Acc:101160492]) HSP 1 Score: 296.975 bits (759), Expect = 2.881e-82 Identity = 189/503 (37.57%), Postives = 270/503 (53.68%), Query Frame = 3
Query: 861 CLSQPEMNEWLTKIKQRINPNYKNSTRHEDLLQIWIQEAKQLIQKKRYYCEIKLDEMLYGRTTIKTVTDTVFWGEEFEFRGLQNINKITICLYKMTDNKKKHERSELVAQIEVPCADLTDSSPCEKWYSPPFQYSNLRLSQSELTNSQKVKLDELLKNAVDIAPMIRIKGRYRPLEILPNKFYDSLSDFLVKQSIPLVESLESHLKVKSKEDFVKILLVILKSKDCHIDFLADLVFIEVSKAED--NLILRGNSIASKAMECYLKMVGEKYLATILKDLINEVIFEEIDCEVDPLRLNNSKENSQIFENQNKLLRLVENVWSKIYHNAHLIPNELKLVFTKIREKLSETKRGSSYSSPMIYQVISSCLFLRFICPAIMSPFLFGLSNEYPDNVSINRTFTLIAKSIQSLANFSQFPQSKETYMEFMQNFINKNSSSMRSFLKLIS-LNKSNGAKSMESQDVLYLLLETDKINYSPTKDDRYIDIGYHLA-------ELMFQLN 2339
C S E ++W+ +++ + PN NS R +++L++WI EA+ L KKRYYCE+ LD+MLY RTT K TDTVFWGE FEF L I + + LYK TD K++ E+S + + +P + +T E+WY P Q S L++ S KV I +RIK RY+ + ILP + Y ++++ L LE L VKSKE+ L+ IL+S +FL+D+ E + D +LI R N++A+KA+E YLK++G +YL + D I + E +CEVDP+R+ S + ++Q L E + KI ++ + P ELK VF R + +E R S +ISS LFLRF+CPAIMSP LF L EYP + +RT TLIA+ +Q+LA+FS+F KE YM FM F+ SM+ FL IS L+ A E YID+G L+ E+M QL+
Sbjct: 167 CRSASERDKWIENLQRAVKPNKDNSRRVDNVLKLWIIEARDLPAKKRYYCELCLDDMLYARTTSKPRTDTVFWGEHFEFNNLPTIRSLRLHLYKETDKKRRKEKSTYIGLVSIPISSITGRQFVEQWY-PVIQSSV--LAKGGGVGSTKV-----------INASLRIKSRYQTMNILPMELYKEFAEYITNNYRTLCAVLEPLLSVKSKEEVAFALVHILQSTGKTKEFLSDMAMCEADRFMDREHLIFRENTLATKAVEEYLKLIGHRYLKEAIGDFIRALYESEENCEVDPMRV----PPSVLADHQANLRMCCELLLCKIINSLCIFPRELKEVFASWRARCAERGREDLADS-----LISSSLFLRFMCPAIMSPSLFSLMQEYPAERT-SRTLTLIARVMQNLASFSKF-GPKEEYMYFMNEFLEMEWGSMQQFLYEISNLDTGGNAGGFEG----------------------YIDLGRELSMLHSLLWEVMGQLS 622
BLAST of Disabled 2-interacting protein vs. Planmine SMEST
Match: SMESG000043888.1 (SMESG000043888.1) HSP 1 Score: 2365.88 bits (6130), Expect = 0.000e+0 Identity = 1254/1266 (99.05%), Postives = 1258/1266 (99.37%), Query Frame = 3
Query: 117 MNFSDRNHFSRKSDPTYRNKKSKEAPVSDNMDSIQNIKRKGASLVRPDFNRQNSLGISNREYTSKRISVFENTKSDGGNHSGGTKIMNFXXXXXXXXXXXXXXXXXXXDSQQVFYNQSISSKSDDHLNVLTDENSFHFVKSANLVLKTKDNTLYVKEYSTNKEFNLKSLTVLDNQSLVQTLHSSLTNHQNFCFQIIKKEQTLDLAKPFCSVTVGXXXXXXXXXXXXXXXXXXXXXXXXXXTDSVINIRCLSQPEMNEWLTKIKQRINPNYKNSTRHEDLLQIWIQEAKQLIQKKRYYCEIKLDEMLYGRTTIKTVTDTVFWGEEFEFRGLQNINKITICLYKMTDNKKKHERSELVAQIEVPCADLTDSSPCEKWYSPPFQYSNLRLSQSELTNSQKVKLDELLKNAVDIAPMIRIKGRYRPLEILPNKFYDSLSDFLVKQSIPLVESLESHLKVKSKEDFVKILLVILKSKDCHIDFLADLVFIEVSKAEDNLILRGNSIASKAMECYLKMVGEKYLATILKDLINEVIFEEIDCEVDPLRLNNSKENSQIFENQNKLLRLVENVWSKIYHNAHLIPNELKLVFTKIREKLSETKRGSSYSSPMIYQVISSCLFLRFICPAIMSPFLFGLSNEYPDNVSINRTFTLIAKSIQSLANFSQFPQSKETYMEFMQNFINKNSSSMRSFLKLISLNKSNGAKSMESQDVLYLLLETDKINYSPTKDDRYIDIGYHLAELMFQLNIHLKDIPDKEYTPTLTEARTIIENITKLSVHNESDCESDSSNISNFNGVASRIPMLISKSDKTANNHYKPLIRIQSQNHSRPMSLMKQKSEIEENFSYIPTKEMETNEPTEERKPQFNNGNYVDFEHFEENRIYDEPCHESIVTTSPCIAKYLNEEEINDDWYKMVKECXXXXXXXXXXLLEDHSNYTQNSSGYQTLANISPDYFENSKIQSQNSDDYIQVENSTXXXXXXXXXXXXXXXXXXIHHKLAYKRIKKGSPLVKKTSSYYTDFKTSNSLNVTSPTDISDIPNVFCTSYETLASSENLSETENLTIPESKSFQAIYQKKSGSNNNLQSLQHEISISTSHDSVNGLLSSKTKFRSRNSQSFQNIFSTNIDLDPLISNEWKRIKLMMKIFNIQKPNQYQGSVIEQYKQRTTDENLLELFLRKKIQINDSDIINYLPTAYRLLKSVHKNGKLTTDVLTQYLMHANHRIQASLITQHLSETNPEPNNEXXXXXXXXXXXXXAHREFSNLSSHSLPFPITKYSK 3914
MNFSDRNHFSRKSDPTYRNKKSKEAPVSDNMDSIQNIKRKGASLVRPD NRQNSLGISNREYTSKRISVFENTKSDGGNHSGGTKIMNFIKSSLNLAKSKSKSKLNISDSQQVFYNQSISSKSDDHLNVLTDENSFHFVKSANLVLKTKDNTLYVKEYSTNKEFNLKSLTVLDNQSLVQTLHSSLTNHQNFCFQIIKKEQTLDLAKPFCSVTVGTSQTTQISKSISFNSSFSSLKPESLETDSVINIRCLSQPEMNEWLTKIKQRINPNYKNSTRHEDLLQIWIQEAKQLIQKKRYYCEIKLDEMLYGRTTIKTVTDTVFWGEEFEFRGLQNINKITICLYKMTDNKKKHERSELVAQIEVPCADLTDSSPCEKWYSPPFQYSNLRLSQSELTNSQKVKLDELLKNAVDIAPMIRIKGRYRPLEILPNKFYDSLSDFLVKQSIPLVESLESHLKVKSKEDFVKILLVILKSKDCHIDFLADLVFIEVSKAEDNLILRGNSIASKAMECYLKMVGEKYLAT+LKDLINEVIFEEIDCEVDPLRLNNSKENSQIFENQNKLLRLVENVWSKIYHNAHLIPNELKLVFTKIREKLSETKRGSSYSSPMIYQVISSCLFLRFICPAIMSPFLFGLSNEYPDNVSINRTFTLIAKSIQSLANFSQFPQSKETYMEFMQNFINKNSSSMRSFLKLISLNKSNGAKSMESQDVLYLLLETD INYSPTKDDRYIDIGYHLAELMFQLNIHLKDIPDKEYTPTLTEARTIIENITKLSVHNESDCESDSSNISNFNGVASRIPMLISKSDKTANN+YKPLIRIQSQNHSRPMSL+KQKSEIEENFSYIPTKEMET EPTEERKPQFNNGNYVDFEHFEENRIYDEPCHESIVTTSPCIAKYLNEEEINDDWYKMVKECSNTSANSNNSLLEDHSNYTQNSSGYQTLANISPDYFENSKIQSQNSDDYIQVENSTSVLASSLPVKLSSSKSSPIHHKLAYKRIKKGSPLVKKTSSY TDFKTSNSLNVTSPTDISDIPNVFCTSYETLASSENLSETENLTIPESKSFQAIYQKKSGSNNNLQSLQHEISISTS DSVNGL SSKTKF+SRNSQSFQNIFSTNIDLDPLISNEWKRIKLMMKIFNIQKPNQYQGSVIEQYKQRT DENLLELFLRKKIQINDSDIINYLPTAYRLLKSVHKNGKLTTDVLTQYLMHANHRIQASLITQHLSETNPEPNNESKSSISKKSRDSKA REFSNLSSHSLPFPITKYSK
Sbjct: 1 MNFSDRNHFSRKSDPTYRNKKSKEAPVSDNMDSIQNIKRKGASLVRPDLNRQNSLGISNREYTSKRISVFENTKSDGGNHSGGTKIMNFIKSSLNLAKSKSKSKLNISDSQQVFYNQSISSKSDDHLNVLTDENSFHFVKSANLVLKTKDNTLYVKEYSTNKEFNLKSLTVLDNQSLVQTLHSSLTNHQNFCFQIIKKEQTLDLAKPFCSVTVGTSQTTQISKSISFNSSFSSLKPESLETDSVINIRCLSQPEMNEWLTKIKQRINPNYKNSTRHEDLLQIWIQEAKQLIQKKRYYCEIKLDEMLYGRTTIKTVTDTVFWGEEFEFRGLQNINKITICLYKMTDNKKKHERSELVAQIEVPCADLTDSSPCEKWYSPPFQYSNLRLSQSELTNSQKVKLDELLKNAVDIAPMIRIKGRYRPLEILPNKFYDSLSDFLVKQSIPLVESLESHLKVKSKEDFVKILLVILKSKDCHIDFLADLVFIEVSKAEDNLILRGNSIASKAMECYLKMVGEKYLATLLKDLINEVIFEEIDCEVDPLRLNNSKENSQIFENQNKLLRLVENVWSKIYHNAHLIPNELKLVFTKIREKLSETKRGSSYSSPMIYQVISSCLFLRFICPAIMSPFLFGLSNEYPDNVSINRTFTLIAKSIQSLANFSQFPQSKETYMEFMQNFINKNSSSMRSFLKLISLNKSNGAKSMESQDVLYLLLETDNINYSPTKDDRYIDIGYHLAELMFQLNIHLKDIPDKEYTPTLTEARTIIENITKLSVHNESDCESDSSNISNFNGVASRIPMLISKSDKTANNNYKPLIRIQSQNHSRPMSLVKQKSEIEENFSYIPTKEMETKEPTEERKPQFNNGNYVDFEHFEENRIYDEPCHESIVTTSPCIAKYLNEEEINDDWYKMVKECSNTSANSNNSLLEDHSNYTQNSSGYQTLANISPDYFENSKIQSQNSDDYIQVENSTSVLASSLPVKLSSSKSSPIHHKLAYKRIKKGSPLVKKTSSYSTDFKTSNSLNVTSPTDISDIPNVFCTSYETLASSENLSETENLTIPESKSFQAIYQKKSGSNNNLQSLQHEISISTSQDSVNGLFSSKTKFKSRNSQSFQNIFSTNIDLDPLISNEWKRIKLMMKIFNIQKPNQYQGSVIEQYKQRTIDENLLELFLRKKIQINDSDIINYLPTAYRLLKSVHKNGKLTTDVLTQYLMHANHRIQASLITQHLSETNPEPNNESKSSISKKSRDSKARREFSNLSSHSLPFPITKYSK 1266
BLAST of Disabled 2-interacting protein vs. Planmine SMEST
Match: SMESG000037132.1 (SMESG000037132.1) HSP 1 Score: 364.385 bits (934), Expect = 3.705e-106 Identity = 218/574 (37.98%), Postives = 331/574 (57.67%), Query Frame = 3
Query: 861 CLSQPEMNEWLTKIKQRINPNYKNSTRHEDLLQIWIQEAKQLIQKKRYYCEIKLDEMLYGRTTIKTVTDTVFWGEEFEFRGLQNINKITICLYKMT-DNKKKHERSE--LVAQIEVPCADLTDSSPCEKWYSPPFQY--SNLRLSQSELTNS-------------QKVKLDELLKNAVDIA-----PMIRIKGRYRPLEILPNKFYDSLSDFLVKQSIPLVESLESHLKVKSKEDFVKILLVILKSKDCHIDFLADLVFIEVSKAE-DNLILRGNSIASKAMECYLKMVGEKYLATILKDLINEVIFEEIDCEVDPLR----------------LNNSKENSQ----IFENQNKLLRLVENVWSKIYHNAHLIPNELKLVFTKIREKLSETKRGSSY----SSPMIYQVISSCLFLRFICPAIMSPFLFGLSNEYPDNVSINRTFTLIAKSIQSLANFSQFPQSKETYMEFMQNFINKNSSSMRSFLKLI--------SLNKSNGAKSMESQDVLYLLLETDKINYSPTKDDRYIDIGYHLAELMFQLNIHLKDIPDKEYTPTLTEARTIIENI 2414
C S+ E +W++ + + + PN +N R E L +WIQEAK + KKRY+CEI LDE L+ +TT KT+TD +FWGEEF L+ +N +TI L+K + DN+ K ++S+ L+ Q+ + D++ + E+WY Y S + S +++S Q + L ++ ++ PMIRIK RY+ +++LP Y L +FL + ++ L++ +++HLKVK+KED L+ +L + +FL+DL+F E+ K++ +N+ILRGN+IASKA+E YLK++GEKYL+ IL D +N + + DCEVDP R L N ++S + + Q L+ V+ +W+KI ++ P ELK VF +R++L + R ++ S + +++SSC+FLRFICPAI++P LFGL EYPDN + RTFTL+AK IQSLANFS SKE+YM FM FI ++M+SFLK I S +K N S+++ E N S T IDI LA+L Q +L+ IP ++YT + II +I
Sbjct: 248 CSSESERKKWMSVLTRVVRPNLQNERRQEISLNLWIQEAKNVPLKKRYFCEIYLDETLHAKTTTKTMTDLLFWGEEFNLCHLEQVNTVTILLWKASSDNRAKKKKSQQHLICQVNIETKDISARNNVERWYPASCSYNSSGTEIVHSNMSHSIISSTDSTPTSTLQSMHSTNLSQSTASLSNSDHLPMIRIKARYQNIDVLPINKYSHLLEFLKQHAVQLLQEMDAHLKVKNKEDLAISLINVLHKQGIAAEFLSDLLFQEIKKSDNENMILRGNTIASKAIEVYLKLIGEKYLSLILSDFVNRISQGDEDCEVDPQRSKCEFFSNSSLNECQSLQNGDKSSHFHPMLLQRQESLMMNVDMIWAKILSSSIYFPRELKSVFVSLRKRLEQMDRTANQMDNSQSNLYERIVSSCIFLRFICPAILTPSLFGLLPEYPDNPKVLRTFTLVAKCIQSLANFSDLTGSKESYMLFMNTFIENKFTTMQSFLKEISSSTDDDYSRSKWNEPSSVDASKENGGYWE----NLSSTLSLDSIDISLCLAKLHRQFEEYLQVIPVQKYTGNIEMLINIIADI 817
BLAST of Disabled 2-interacting protein vs. Planmine SMEST
Match: SMESG000037132.1 (SMESG000037132.1) HSP 1 Score: 364.385 bits (934), Expect = 5.259e-106 Identity = 218/574 (37.98%), Postives = 331/574 (57.67%), Query Frame = 3
Query: 861 CLSQPEMNEWLTKIKQRINPNYKNSTRHEDLLQIWIQEAKQLIQKKRYYCEIKLDEMLYGRTTIKTVTDTVFWGEEFEFRGLQNINKITICLYKMT-DNKKKHERSE--LVAQIEVPCADLTDSSPCEKWYSPPFQY--SNLRLSQSELTNS-------------QKVKLDELLKNAVDIA-----PMIRIKGRYRPLEILPNKFYDSLSDFLVKQSIPLVESLESHLKVKSKEDFVKILLVILKSKDCHIDFLADLVFIEVSKAE-DNLILRGNSIASKAMECYLKMVGEKYLATILKDLINEVIFEEIDCEVDPLR----------------LNNSKENSQ----IFENQNKLLRLVENVWSKIYHNAHLIPNELKLVFTKIREKLSETKRGSSY----SSPMIYQVISSCLFLRFICPAIMSPFLFGLSNEYPDNVSINRTFTLIAKSIQSLANFSQFPQSKETYMEFMQNFINKNSSSMRSFLKLI--------SLNKSNGAKSMESQDVLYLLLETDKINYSPTKDDRYIDIGYHLAELMFQLNIHLKDIPDKEYTPTLTEARTIIENI 2414
C S+ E +W++ + + + PN +N R E L +WIQEAK + KKRY+CEI LDE L+ +TT KT+TD +FWGEEF L+ +N +TI L+K + DN+ K ++S+ L+ Q+ + D++ + E+WY Y S + S +++S Q + L ++ ++ PMIRIK RY+ +++LP Y L +FL + ++ L++ +++HLKVK+KED L+ +L + +FL+DL+F E+ K++ +N+ILRGN+IASKA+E YLK++GEKYL+ IL D +N + + DCEVDP R L N ++S + + Q L+ V+ +W+KI ++ P ELK VF +R++L + R ++ S + +++SSC+FLRFICPAI++P LFGL EYPDN + RTFTL+AK IQSLANFS SKE+YM FM FI ++M+SFLK I S +K N S+++ E N S T IDI LA+L Q +L+ IP ++YT + II +I
Sbjct: 248 CSSESERKKWMSVLTRVVRPNLQNERRQEISLNLWIQEAKNVPLKKRYFCEIYLDETLHAKTTTKTMTDLLFWGEEFNLCHLEQVNTVTILLWKASSDNRAKKKKSQQHLICQVNIETKDISARNNVERWYPASCSYNSSGTEIVHSNMSHSIISSTDSTPTSTLQSMHSTNLSQSTASLSNSDHLPMIRIKARYQNIDVLPINKYSHLLEFLKQHAVQLLQEMDAHLKVKNKEDLAISLINVLHKQGIAAEFLSDLLFQEIKKSDNENMILRGNTIASKAIEVYLKLIGEKYLSLILSDFVNRISQGDEDCEVDPQRSKCEFFSNSSLNECQSLQNGDKSSHFHPMLLQRQESLMMNVDMIWAKILSSSIYFPRELKSVFVSLRKRLEQMDRTANQMDNSQSNLYERIVSSCIFLRFICPAILTPSLFGLLPEYPDNPKVLRTFTLVAKCIQSLANFSDLTGSKESYMLFMNTFIENKFTTMQSFLKEISSSTDDDYSRSKWNEPSSVDASKENGGYWE----NLSSTLSLDSIDISLCLAKLHRQFEEYLQVIPVQKYTGNIEMLINIIADI 817
BLAST of Disabled 2-interacting protein vs. Planmine SMEST
Match: SMESG000037132.1 (SMESG000037132.1) HSP 1 Score: 363.614 bits (932), Expect = 6.861e-106 Identity = 218/574 (37.98%), Postives = 331/574 (57.67%), Query Frame = 3
Query: 861 CLSQPEMNEWLTKIKQRINPNYKNSTRHEDLLQIWIQEAKQLIQKKRYYCEIKLDEMLYGRTTIKTVTDTVFWGEEFEFRGLQNINKITICLYKMT-DNKKKHERSE--LVAQIEVPCADLTDSSPCEKWYSPPFQY--SNLRLSQSELTNS-------------QKVKLDELLKNAVDIA-----PMIRIKGRYRPLEILPNKFYDSLSDFLVKQSIPLVESLESHLKVKSKEDFVKILLVILKSKDCHIDFLADLVFIEVSKAE-DNLILRGNSIASKAMECYLKMVGEKYLATILKDLINEVIFEEIDCEVDPLR----------------LNNSKENSQ----IFENQNKLLRLVENVWSKIYHNAHLIPNELKLVFTKIREKLSETKRGSSY----SSPMIYQVISSCLFLRFICPAIMSPFLFGLSNEYPDNVSINRTFTLIAKSIQSLANFSQFPQSKETYMEFMQNFINKNSSSMRSFLKLI--------SLNKSNGAKSMESQDVLYLLLETDKINYSPTKDDRYIDIGYHLAELMFQLNIHLKDIPDKEYTPTLTEARTIIENI 2414
C S+ E +W++ + + + PN +N R E L +WIQEAK + KKRY+CEI LDE L+ +TT KT+TD +FWGEEF L+ +N +TI L+K + DN+ K ++S+ L+ Q+ + D++ + E+WY Y S + S +++S Q + L ++ ++ PMIRIK RY+ +++LP Y L +FL + ++ L++ +++HLKVK+KED L+ +L + +FL+DL+F E+ K++ +N+ILRGN+IASKA+E YLK++GEKYL+ IL D +N + + DCEVDP R L N ++S + + Q L+ V+ +W+KI ++ P ELK VF +R++L + R ++ S + +++SSC+FLRFICPAI++P LFGL EYPDN + RTFTL+AK IQSLANFS SKE+YM FM FI ++M+SFLK I S +K N S+++ E N S T IDI LA+L Q +L+ IP ++YT + II +I
Sbjct: 248 CSSESERKKWMSVLTRVVRPNLQNERRQEISLNLWIQEAKNVPLKKRYFCEIYLDETLHAKTTTKTMTDLLFWGEEFNLCHLEQVNTVTILLWKASSDNRAKKKKSQQHLICQVNIETKDISARNNVERWYPASCSYNSSGTEIVHSNMSHSIISSTDSTPTSTLQSMHSTNLSQSTASLSNSDHLPMIRIKARYQNIDVLPINKYSHLLEFLKQHAVQLLQEMDAHLKVKNKEDLAISLINVLHKQGIAAEFLSDLLFQEIKKSDNENMILRGNTIASKAIEVYLKLIGEKYLSLILSDFVNRISQGDEDCEVDPQRSKCEFFSNSSLNECQSLQNGDKSSHFHPMLLQRQESLMMNVDMIWAKILSSSIYFPRELKSVFVSLRKRLEQMDRTANQMDNSQSNLYERIVSSCIFLRFICPAILTPSLFGLLPEYPDNPKVLRTFTLVAKCIQSLANFSDLTGSKESYMLFMNTFIENKFTTMQSFLKEISSSTDDDYSRSKWNEPSSVDASKENGGYWE----NLSSTLSLDSIDISLCLAKLHRQFEEYLQVIPVQKYTGNIEMLINIIADI 817
BLAST of Disabled 2-interacting protein vs. Planmine SMEST
Match: SMESG000037132.1 (SMESG000037132.1) HSP 1 Score: 363.999 bits (933), Expect = 7.259e-106 Identity = 218/574 (37.98%), Postives = 331/574 (57.67%), Query Frame = 3
Query: 861 CLSQPEMNEWLTKIKQRINPNYKNSTRHEDLLQIWIQEAKQLIQKKRYYCEIKLDEMLYGRTTIKTVTDTVFWGEEFEFRGLQNINKITICLYKMT-DNKKKHERSE--LVAQIEVPCADLTDSSPCEKWYSPPFQY--SNLRLSQSELTNS-------------QKVKLDELLKNAVDIA-----PMIRIKGRYRPLEILPNKFYDSLSDFLVKQSIPLVESLESHLKVKSKEDFVKILLVILKSKDCHIDFLADLVFIEVSKAE-DNLILRGNSIASKAMECYLKMVGEKYLATILKDLINEVIFEEIDCEVDPLR----------------LNNSKENSQ----IFENQNKLLRLVENVWSKIYHNAHLIPNELKLVFTKIREKLSETKRGSSY----SSPMIYQVISSCLFLRFICPAIMSPFLFGLSNEYPDNVSINRTFTLIAKSIQSLANFSQFPQSKETYMEFMQNFINKNSSSMRSFLKLI--------SLNKSNGAKSMESQDVLYLLLETDKINYSPTKDDRYIDIGYHLAELMFQLNIHLKDIPDKEYTPTLTEARTIIENI 2414
C S+ E +W++ + + + PN +N R E L +WIQEAK + KKRY+CEI LDE L+ +TT KT+TD +FWGEEF L+ +N +TI L+K + DN+ K ++S+ L+ Q+ + D++ + E+WY Y S + S +++S Q + L ++ ++ PMIRIK RY+ +++LP Y L +FL + ++ L++ +++HLKVK+KED L+ +L + +FL+DL+F E+ K++ +N+ILRGN+IASKA+E YLK++GEKYL+ IL D +N + + DCEVDP R L N ++S + + Q L+ V+ +W+KI ++ P ELK VF +R++L + R ++ S + +++SSC+FLRFICPAI++P LFGL EYPDN + RTFTL+AK IQSLANFS SKE+YM FM FI ++M+SFLK I S +K N S+++ E N S T IDI LA+L Q +L+ IP ++YT + II +I
Sbjct: 248 CSSESERKKWMSVLTRVVRPNLQNERRQEISLNLWIQEAKNVPLKKRYFCEIYLDETLHAKTTTKTMTDLLFWGEEFNLCHLEQVNTVTILLWKASSDNRAKKKKSQQHLICQVNIETKDISARNNVERWYPASCSYNSSGTEIVHSNMSHSIISSTDSTPTSTLQSMHSTNLSQSTASLSNSDHLPMIRIKARYQNIDVLPINKYSHLLEFLKQHAVQLLQEMDAHLKVKNKEDLAISLINVLHKQGIAAEFLSDLLFQEIKKSDNENMILRGNTIASKAIEVYLKLIGEKYLSLILSDFVNRISQGDEDCEVDPQRSKCEFFSNSSLNECQSLQNGDKSSHFHPMLLQRQESLMMNVDMIWAKILSSSIYFPRELKSVFVSLRKRLEQMDRTANQMDNSQSNLYERIVSSCIFLRFICPAILTPSLFGLLPEYPDNPKVLRTFTLVAKCIQSLANFSDLTGSKESYMLFMNTFIENKFTTMQSFLKEISSSTDDDYSRSKWNEPSSVDASKENGGYWE----NLSSTLSLDSIDISLCLAKLHRQFEEYLQVIPVQKYTGNIEMLINIIADI 817 The following BLAST results are available for this feature:
BLAST of Disabled 2-interacting protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Disabled 2-interacting protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Disabled 2-interacting protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Disabled 2-interacting protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Disabled 2-interacting protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Disabled 2-interacting protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Disabled 2-interacting protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Disabled 2-interacting protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Disabled 2-interacting protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Disabled 2-interacting protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 1
BLAST of Disabled 2-interacting protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 2
BLAST of Disabled 2-interacting protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 4
BLAST of Disabled 2-interacting protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Disabled 2-interacting protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30017369 ID=SMED30017369|Name=Disabled 2-interacting protein|organism=Schmidtea mediterranea sexual|type=transcript|length=4074bpback to top protein sequence of SMED30017369-orf-1 >SMED30017369-orf-1 ID=SMED30017369-orf-1|Name=SMED30017369-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=1267bp MNFSDRNHFSRKSDPTYRNKKSKEAPVSDNMDSIQNIKRKGASLVRPDFNback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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