Tyrosine-protein kinase
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30017367 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 3
Homology
BLAST of Tyrosine-protein kinase vs. Ensembl Human
Match: CSK (C-terminal Src kinase [Source:HGNC Symbol;Acc:HGNC:2444]) HSP 1 Score: 361.688 bits (927), Expect = 3.382e-119 Identity = 192/474 (40.51%), Postives = 268/474 (56.54%), Query Frame = 1
Query: 79 ALYNFEGQKAEDLPFSKGEKLKVLKIISDPNWITCSNNKQHQGLVPVNHVKLSPSLNIED-----PWYHGKVSRSLAEERLMPCENGTFLIRSSDKFPGDYTICVKFND-VQFYHVIYSNKGYTLDEDSWFASMPELIEHYQKDADGLCCTLTK--CYESPKSRLDYLDENVLNIKFEEIKLGPKIGCGEFSEVLQGEYQDTVVAVKCLKKPINFAEKTLFTFEFSLMAKLNHPHLVTFKG-ISSSNESVYIITEYMENGSLVNYLRSRGRTVIKTNDQIKFAIDSCSGMCYLEEHCLVHRDLAARNILLNAKLVAKVSDFGLARVDDXXXXXXXXXXXXXXXXXXXXXKTPSPKLMLNVVNDLVSLPTSSVDDNTTSVGRIPVKWTAPEALTHNKYTNKSDVWSFGILLWEIFSFGRTPYPRIYANNVKQHLLNGYRMESPEDTPNDIYELMRDCWALEPEKRPTFCEIHKIL 1473
A YNF G +DLPF KG+ L ++ + DPNW N +G++P N+V+ + PW+HGK++R AE L P E G FL+R S +PGDYT+CV + V+ Y ++Y ++DE+ +F ++ +L+EHY DADGLC L K E + D + + +E+KL IG GEF +V+ G+Y+ VAVKC+K N A F E S+M +L H +LV G I +YI+TEYM GSLV+YLRSRGR+V+ + +KF++D C M YLE + VHRDLAARN+L++ VAKVSDFGL + SS D G++PVKWTAPEAL K++ KSDVWSFGILLWEI+SFGR PYPRI +V + GY+M++P+ P +YE+M++CW L+ RP+F ++ + L
Sbjct: 16 AKYNFHGTAEQDLPFCKGDVLTIVAVTKDPNWYKAKNKVGREGIIPANYVQKREGVKAGTKLSLMPWFHGKITREQAERLLYPPETGLFLVRESTNYPGDYTLCVSCDGKVEHYRIMYHASKLSIDEEVYFENLMQLVEHYTSDADGLCTRLIKPKVMEGTVAAQDEFYRSGWALNMKELKLLQTIGKGEFGDVMLGDYRGNKVAVKCIK---NDATAQAFLAEASVMTQLRHSNLVQLLGVIVEEKGGLYIVTEYMAKGSLVDYLRSRGRSVLGGDCLLKFSLDVCEAMEYLEGNNFVHRDLAARNVLVSEDNVAKVSDFGLTK------------------------------------------EASSTQDT----GKLPVKWTAPEALREKKFSTKSDVWSFGILLWEIYSFGRVPYPRIPLKDVVPRVEKGYKMDAPDGCPPAVYEVMKNCWHLDAAMRPSFLQLREQL 440
BLAST of Tyrosine-protein kinase vs. Ensembl Human
Match: CSK (C-terminal Src kinase [Source:HGNC Symbol;Acc:HGNC:2444]) HSP 1 Score: 361.688 bits (927), Expect = 3.382e-119 Identity = 192/474 (40.51%), Postives = 268/474 (56.54%), Query Frame = 1
Query: 79 ALYNFEGQKAEDLPFSKGEKLKVLKIISDPNWITCSNNKQHQGLVPVNHVKLSPSLNIED-----PWYHGKVSRSLAEERLMPCENGTFLIRSSDKFPGDYTICVKFND-VQFYHVIYSNKGYTLDEDSWFASMPELIEHYQKDADGLCCTLTK--CYESPKSRLDYLDENVLNIKFEEIKLGPKIGCGEFSEVLQGEYQDTVVAVKCLKKPINFAEKTLFTFEFSLMAKLNHPHLVTFKG-ISSSNESVYIITEYMENGSLVNYLRSRGRTVIKTNDQIKFAIDSCSGMCYLEEHCLVHRDLAARNILLNAKLVAKVSDFGLARVDDXXXXXXXXXXXXXXXXXXXXXKTPSPKLMLNVVNDLVSLPTSSVDDNTTSVGRIPVKWTAPEALTHNKYTNKSDVWSFGILLWEIFSFGRTPYPRIYANNVKQHLLNGYRMESPEDTPNDIYELMRDCWALEPEKRPTFCEIHKIL 1473
A YNF G +DLPF KG+ L ++ + DPNW N +G++P N+V+ + PW+HGK++R AE L P E G FL+R S +PGDYT+CV + V+ Y ++Y ++DE+ +F ++ +L+EHY DADGLC L K E + D + + +E+KL IG GEF +V+ G+Y+ VAVKC+K N A F E S+M +L H +LV G I +YI+TEYM GSLV+YLRSRGR+V+ + +KF++D C M YLE + VHRDLAARN+L++ VAKVSDFGL + SS D G++PVKWTAPEAL K++ KSDVWSFGILLWEI+SFGR PYPRI +V + GY+M++P+ P +YE+M++CW L+ RP+F ++ + L
Sbjct: 16 AKYNFHGTAEQDLPFCKGDVLTIVAVTKDPNWYKAKNKVGREGIIPANYVQKREGVKAGTKLSLMPWFHGKITREQAERLLYPPETGLFLVRESTNYPGDYTLCVSCDGKVEHYRIMYHASKLSIDEEVYFENLMQLVEHYTSDADGLCTRLIKPKVMEGTVAAQDEFYRSGWALNMKELKLLQTIGKGEFGDVMLGDYRGNKVAVKCIK---NDATAQAFLAEASVMTQLRHSNLVQLLGVIVEEKGGLYIVTEYMAKGSLVDYLRSRGRSVLGGDCLLKFSLDVCEAMEYLEGNNFVHRDLAARNVLVSEDNVAKVSDFGLTK------------------------------------------EASSTQDT----GKLPVKWTAPEALREKKFSTKSDVWSFGILLWEIYSFGRVPYPRIPLKDVVPRVEKGYKMDAPDGCPPAVYEVMKNCWHLDAAMRPSFLQLREQL 440
BLAST of Tyrosine-protein kinase vs. Ensembl Human
Match: CSK (C-terminal Src kinase [Source:HGNC Symbol;Acc:HGNC:2444]) HSP 1 Score: 361.688 bits (927), Expect = 3.382e-119 Identity = 192/474 (40.51%), Postives = 268/474 (56.54%), Query Frame = 1
Query: 79 ALYNFEGQKAEDLPFSKGEKLKVLKIISDPNWITCSNNKQHQGLVPVNHVKLSPSLNIED-----PWYHGKVSRSLAEERLMPCENGTFLIRSSDKFPGDYTICVKFND-VQFYHVIYSNKGYTLDEDSWFASMPELIEHYQKDADGLCCTLTK--CYESPKSRLDYLDENVLNIKFEEIKLGPKIGCGEFSEVLQGEYQDTVVAVKCLKKPINFAEKTLFTFEFSLMAKLNHPHLVTFKG-ISSSNESVYIITEYMENGSLVNYLRSRGRTVIKTNDQIKFAIDSCSGMCYLEEHCLVHRDLAARNILLNAKLVAKVSDFGLARVDDXXXXXXXXXXXXXXXXXXXXXKTPSPKLMLNVVNDLVSLPTSSVDDNTTSVGRIPVKWTAPEALTHNKYTNKSDVWSFGILLWEIFSFGRTPYPRIYANNVKQHLLNGYRMESPEDTPNDIYELMRDCWALEPEKRPTFCEIHKIL 1473
A YNF G +DLPF KG+ L ++ + DPNW N +G++P N+V+ + PW+HGK++R AE L P E G FL+R S +PGDYT+CV + V+ Y ++Y ++DE+ +F ++ +L+EHY DADGLC L K E + D + + +E+KL IG GEF +V+ G+Y+ VAVKC+K N A F E S+M +L H +LV G I +YI+TEYM GSLV+YLRSRGR+V+ + +KF++D C M YLE + VHRDLAARN+L++ VAKVSDFGL + SS D G++PVKWTAPEAL K++ KSDVWSFGILLWEI+SFGR PYPRI +V + GY+M++P+ P +YE+M++CW L+ RP+F ++ + L
Sbjct: 16 AKYNFHGTAEQDLPFCKGDVLTIVAVTKDPNWYKAKNKVGREGIIPANYVQKREGVKAGTKLSLMPWFHGKITREQAERLLYPPETGLFLVRESTNYPGDYTLCVSCDGKVEHYRIMYHASKLSIDEEVYFENLMQLVEHYTSDADGLCTRLIKPKVMEGTVAAQDEFYRSGWALNMKELKLLQTIGKGEFGDVMLGDYRGNKVAVKCIK---NDATAQAFLAEASVMTQLRHSNLVQLLGVIVEEKGGLYIVTEYMAKGSLVDYLRSRGRSVLGGDCLLKFSLDVCEAMEYLEGNNFVHRDLAARNVLVSEDNVAKVSDFGLTK------------------------------------------EASSTQDT----GKLPVKWTAPEALREKKFSTKSDVWSFGILLWEIYSFGRVPYPRIPLKDVVPRVEKGYKMDAPDGCPPAVYEVMKNCWHLDAAMRPSFLQLREQL 440
BLAST of Tyrosine-protein kinase vs. Ensembl Human
Match: MATK (megakaryocyte-associated tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:6906]) HSP 1 Score: 318.546 bits (815), Expect = 3.049e-102 Identity = 174/472 (36.86%), Postives = 261/472 (55.30%), Query Frame = 1
Query: 103 KAEDLPFSKGEKLKVLKIISDPNWITCSNNKQHQ-GLVPVNHVKLSPSLNIED-----PWYHGKVSRSLAEERLMPCENGTFLIRSSDKFPGDYTICVKFN-DVQFYHVIYSNKGYTLDEDSWFASMPELIEHYQKDADGLCCTLT--KCYESPKSRLDYLDENVLNIKFEEIKLGPKIGCGEFSEVLQGEYQDTVVAVKCLKKPINFAEKTLFTFEFSLMAKLNHPHLVTFKGISSSNESVYIITEYMENGSLVNYLRSRGRTVIKTNDQIKFAIDSCSGMCYLEEHCLVHRDLAARNILLNAKLVAKVSDFGLARVDDXXXXXXXXXXXXXXXXXXXXXKTPSPKLMLNVVNDLVSLPTSSVDDNTTSVGRIPVKWTAPEALTHNKYTNKSDVWSFGILLWEIFSFGRTPYPRIYANNVKQHLLNGYRMESPEDTPNDIYELMRDCWALEPEKRPTFCEIHKILHKKMKS 1491
K +L F KG+ + +L+ + +W ++ Q GL+ ++ +L+ + PW+HGK+S A ++L P E+G FL+R S + PGDY +CV F DV Y V++ + T+DE +F ++ +++EHY KD +C L K KS + L + + + LG +IG GEF VLQGEY VAVK +K + F E ++M K+ H +LV G+ ++ +YI+ E++ G+LVN+LR+RGR ++ T ++F++ GM YLE LVHRDLAARNIL++ LVAKVSDFGLA+ + +D + R+PVKWTAPEAL H K+T+KSDVWSFG+LLWE+FS+GR PYP++ V + + GYRME PE P ++ LM CW EP +RP F ++ + L ++++S
Sbjct: 22 KPGELAFRKGDVVTILEACENKSWYRVKHHTSGQEGLLAAGALREREALSADPKLSLMPWFHGKISGQEAVQQLQPPEDGLFLVRESARHPGDYVLCVSFGRDVIHYRVLHRDGHLTIDEAVFFCNLMDMVEHYSKDKGAICTKLVRPKRKHGTKSAEEELARAGWLLNLQHLTLGAQIGEGEFGAVLQGEYLGQKVAVKNIKCDVT---AQAFLDETAVMTKMQHENLVRLLGVIL-HQGLYIVMEHVSKGNLVNFLRTRGRALVNTAQLLQFSLHVAEGMEYLESKKLVHRDLAARNILVSEDLVAKVSDFGLAKAE-----------------------------------------RKGLDSS-----RLPVKWTAPEALKHGKFTSKSDVWSFGVLLWEVFSYGRAPYPKMSLKEVSEAVEKGYRMEPPEGCPGPVHVLMSSCWEAEPARRPPFRKLAEKLARELRS 443
BLAST of Tyrosine-protein kinase vs. Ensembl Human
Match: MATK (megakaryocyte-associated tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:6906]) HSP 1 Score: 318.161 bits (814), Expect = 1.239e-101 Identity = 174/472 (36.86%), Postives = 261/472 (55.30%), Query Frame = 1
Query: 103 KAEDLPFSKGEKLKVLKIISDPNWITCSNNKQHQ-GLVPVNHVKLSPSLNIED-----PWYHGKVSRSLAEERLMPCENGTFLIRSSDKFPGDYTICVKFN-DVQFYHVIYSNKGYTLDEDSWFASMPELIEHYQKDADGLCCTLT--KCYESPKSRLDYLDENVLNIKFEEIKLGPKIGCGEFSEVLQGEYQDTVVAVKCLKKPINFAEKTLFTFEFSLMAKLNHPHLVTFKGISSSNESVYIITEYMENGSLVNYLRSRGRTVIKTNDQIKFAIDSCSGMCYLEEHCLVHRDLAARNILLNAKLVAKVSDFGLARVDDXXXXXXXXXXXXXXXXXXXXXKTPSPKLMLNVVNDLVSLPTSSVDDNTTSVGRIPVKWTAPEALTHNKYTNKSDVWSFGILLWEIFSFGRTPYPRIYANNVKQHLLNGYRMESPEDTPNDIYELMRDCWALEPEKRPTFCEIHKILHKKMKS 1491
K +L F KG+ + +L+ + +W ++ Q GL+ ++ +L+ + PW+HGK+S A ++L P E+G FL+R S + PGDY +CV F DV Y V++ + T+DE +F ++ +++EHY KD +C L K KS + L + + + LG +IG GEF VLQGEY VAVK +K + F E ++M K+ H +LV G+ ++ +YI+ E++ G+LVN+LR+RGR ++ T ++F++ GM YLE LVHRDLAARNIL++ LVAKVSDFGLA+ + +D + R+PVKWTAPEAL H K+T+KSDVWSFG+LLWE+FS+GR PYP++ V + + GYRME PE P ++ LM CW EP +RP F ++ + L ++++S
Sbjct: 63 KPGELAFRKGDVVTILEACENKSWYRVKHHTSGQEGLLAAGALREREALSADPKLSLMPWFHGKISGQEAVQQLQPPEDGLFLVRESARHPGDYVLCVSFGRDVIHYRVLHRDGHLTIDEAVFFCNLMDMVEHYSKDKGAICTKLVRPKRKHGTKSAEEELARAGWLLNLQHLTLGAQIGEGEFGAVLQGEYLGQKVAVKNIKCDVT---AQAFLDETAVMTKMQHENLVRLLGVIL-HQGLYIVMEHVSKGNLVNFLRTRGRALVNTAQLLQFSLHVAEGMEYLESKKLVHRDLAARNILVSEDLVAKVSDFGLAKAE-----------------------------------------RKGLDSS-----RLPVKWTAPEALKHGKFTSKSDVWSFGVLLWEVFSYGRAPYPKMSLKEVSEAVEKGYRMEPPEGCPGPVHVLMSSCWEAEPARRPPFRKLAEKLARELRS 484
BLAST of Tyrosine-protein kinase vs. Ensembl Celegans
Match: csk-1 (Tyrosine-protein kinase csk-1 [Source:UniProtKB/Swiss-Prot;Acc:G5ECJ6]) HSP 1 Score: 318.931 bits (816), Expect = 6.083e-102 Identity = 182/512 (35.55%), Postives = 265/512 (51.76%), Query Frame = 1
Query: 94 EGQKAEDLPFSKGEKLKVLKIISDPNWITCSNNKQHQGLVPVNHV--------------------KLSPSLNI--------------EDPWYHGKVSRSLAEERLMPCENGTFLIRSSDKFPGDYTICVKFND-VQFYHVIYSNKG-YTLDEDSWFASMPELIEHYQKDADGLCCTLTK---CYESP-----------------KSRLDYLDENVLNIKFEEIKLGPKIGCGEFSEVLQGEYQDTVVAVKCLKKPINFAEKTLFTFEFSLMAKLNHPHLVTFKGISSSNESVYIITEYMENGSLVNYLRSRGRTVIKTNDQIKFAIDSCSGMCYLEEHCLVHRDLAARNILLNAKLVAKVSDFGLARVDDXXXXXXXXXXXXXXXXXXXXXKTPSPKLMLNVVNDLVSLPTSSVDDNTTSVGRIPVKWTAPEALTHNKYTNKSDVWSFGILLWEIFSFGRTPYPRIYANNVKQHLLNGYRMESPEDTPNDIYELMRDCWALEPEKRPTFCEI 1461
G A D F K + +++L +DP W N Q +GLV + V ++P PW+H +SR E+ L +GTFL+R S FPGD+T+C+ F+ V+ Y + ++ G T D++ +F+++ +L+ HY++DADGLC L C + + R L I +I +G IG GEF +V G Y++ VA+K K+ N +L E M L+HP+LVT G+ + +VY+ITEYM NG+L++ LRSRGR ++ + FA+D C GMCYLE +VHRDLAARN+LL+ LVAKVSDFGLA+ ++ + ++ G+ P+KWTAPEAL H+++T KSDVWSFGILLWEIFSFGR PYPRI +V +++ GYRME+PE P +I+++M + WAL + RP+F ++
Sbjct: 61 HGMPARDNVFRKDDHVRILGNTTDPAWYRARNANQEEGLVHADCVVRINGQAYDNGIVRMRASGCDVAPGAASTTSSTSSHHSTAANHQPWFHSMISRENTEKLLRGKPDGTFLVRESTNFPGDFTLCMSFHGKVEHYRIEQTSGGQLTCDKEEYFSNLTQLVSHYKRDADGLCHRLVTPIICETATFSSNGSSSFGSSSTVDLEDRTSVFRHAGLVISSNDIDVGDTIGHGEFGDVRLGTYKNRKVALKVSKRHGNGMLDSLLD-EAKFMVGLSHPNLVTLVGVVLDDVNVYMITEYMANGNLIDLLRSRGRHALERRQLMMFAMDICQGMCYLESKQIVHRDLAARNVLLDDDLVAKVSDFGLAK-------------------------------------------KANSQSHDSASGKFPIKWTAPEALRHSQFTTKSDVWSFGILLWEIFSFGRVPYPRIPIQDVVRYIEKGYRMEAPEGCPPEIFKVMNETWALSAQDRPSFGQV 528
BLAST of Tyrosine-protein kinase vs. Ensembl Celegans
Match: csk-1 (Tyrosine-protein kinase csk-1 [Source:UniProtKB/Swiss-Prot;Acc:G5ECJ6]) HSP 1 Score: 318.931 bits (816), Expect = 6.083e-102 Identity = 182/512 (35.55%), Postives = 265/512 (51.76%), Query Frame = 1
Query: 94 EGQKAEDLPFSKGEKLKVLKIISDPNWITCSNNKQHQGLVPVNHV--------------------KLSPSLNI--------------EDPWYHGKVSRSLAEERLMPCENGTFLIRSSDKFPGDYTICVKFND-VQFYHVIYSNKG-YTLDEDSWFASMPELIEHYQKDADGLCCTLTK---CYESP-----------------KSRLDYLDENVLNIKFEEIKLGPKIGCGEFSEVLQGEYQDTVVAVKCLKKPINFAEKTLFTFEFSLMAKLNHPHLVTFKGISSSNESVYIITEYMENGSLVNYLRSRGRTVIKTNDQIKFAIDSCSGMCYLEEHCLVHRDLAARNILLNAKLVAKVSDFGLARVDDXXXXXXXXXXXXXXXXXXXXXKTPSPKLMLNVVNDLVSLPTSSVDDNTTSVGRIPVKWTAPEALTHNKYTNKSDVWSFGILLWEIFSFGRTPYPRIYANNVKQHLLNGYRMESPEDTPNDIYELMRDCWALEPEKRPTFCEI 1461
G A D F K + +++L +DP W N Q +GLV + V ++P PW+H +SR E+ L +GTFL+R S FPGD+T+C+ F+ V+ Y + ++ G T D++ +F+++ +L+ HY++DADGLC L C + + R L I +I +G IG GEF +V G Y++ VA+K K+ N +L E M L+HP+LVT G+ + +VY+ITEYM NG+L++ LRSRGR ++ + FA+D C GMCYLE +VHRDLAARN+LL+ LVAKVSDFGLA+ ++ + ++ G+ P+KWTAPEAL H+++T KSDVWSFGILLWEIFSFGR PYPRI +V +++ GYRME+PE P +I+++M + WAL + RP+F ++
Sbjct: 61 HGMPARDNVFRKDDHVRILGNTTDPAWYRARNANQEEGLVHADCVVRINGQAYDNGIVRMRASGCDVAPGAASTTSSTSSHHSTAANHQPWFHSMISRENTEKLLRGKPDGTFLVRESTNFPGDFTLCMSFHGKVEHYRIEQTSGGQLTCDKEEYFSNLTQLVSHYKRDADGLCHRLVTPIICETATFSSNGSSSFGSSSTVDLEDRTSVFRHAGLVISSNDIDVGDTIGHGEFGDVRLGTYKNRKVALKVSKRHGNGMLDSLLD-EAKFMVGLSHPNLVTLVGVVLDDVNVYMITEYMANGNLIDLLRSRGRHALERRQLMMFAMDICQGMCYLESKQIVHRDLAARNVLLDDDLVAKVSDFGLAK-------------------------------------------KANSQSHDSASGKFPIKWTAPEALRHSQFTTKSDVWSFGILLWEIFSFGRVPYPRIPIQDVVRYIEKGYRMEAPEGCPPEIFKVMNETWALSAQDRPSFGQV 528
BLAST of Tyrosine-protein kinase vs. Ensembl Celegans
Match: csk-1 (Tyrosine-protein kinase csk-1 [Source:UniProtKB/Swiss-Prot;Acc:G5ECJ6]) HSP 1 Score: 318.931 bits (816), Expect = 5.977e-101 Identity = 182/511 (35.62%), Postives = 265/511 (51.86%), Query Frame = 1
Query: 97 GQKAEDLPFSKGEKLKVLKIISDPNWITCSNNKQHQGLVPVNHV--------------------KLSPSLNI--------------EDPWYHGKVSRSLAEERLMPCENGTFLIRSSDKFPGDYTICVKFND-VQFYHVIYSNKGY-TLDEDSWFASMPELIEHYQKDADGLCCTLTK---CYESP-----------------KSRLDYLDENVLNIKFEEIKLGPKIGCGEFSEVLQGEYQDTVVAVKCLKKPINFAEKTLFTFEFSLMAKLNHPHLVTFKGISSSNESVYIITEYMENGSLVNYLRSRGRTVIKTNDQIKFAIDSCSGMCYLEEHCLVHRDLAARNILLNAKLVAKVSDFGLARVDDXXXXXXXXXXXXXXXXXXXXXKTPSPKLMLNVVNDLVSLPTSSVDDNTTSVGRIPVKWTAPEALTHNKYTNKSDVWSFGILLWEIFSFGRTPYPRIYANNVKQHLLNGYRMESPEDTPNDIYELMRDCWALEPEKRPTFCEI 1461
G A D F K + +++L +DP W N Q +GLV + V ++P PW+H +SR E+ L +GTFL+R S FPGD+T+C+ F+ V+ Y + ++ G T D++ +F+++ +L+ HY++DADGLC L C + + R L I +I +G IG GEF +V G Y++ VA+K K+ N +L E M L+HP+LVT G+ + +VY+ITEYM NG+L++ LRSRGR ++ + FA+D C GMCYLE +VHRDLAARN+LL+ LVAKVSDFGLA+ ++ + ++ G+ P+KWTAPEAL H+++T KSDVWSFGILLWEIFSFGR PYPRI +V +++ GYRME+PE P +I+++M + WAL + RP+F ++
Sbjct: 147 GMPARDNVFRKDDHVRILGNTTDPAWYRARNANQEEGLVHADCVVRINGQAYDNGIVRMRASGCDVAPGAASTTSSTSSHHSTAANHQPWFHSMISRENTEKLLRGKPDGTFLVRESTNFPGDFTLCMSFHGKVEHYRIEQTSGGQLTCDKEEYFSNLTQLVSHYKRDADGLCHRLVTPIICETATFSSNGSSSFGSSSTVDLEDRTSVFRHAGLVISSNDIDVGDTIGHGEFGDVRLGTYKNRKVALKVSKRHGNGMLDSLLD-EAKFMVGLSHPNLVTLVGVVLDDVNVYMITEYMANGNLIDLLRSRGRHALERRQLMMFAMDICQGMCYLESKQIVHRDLAARNVLLDDDLVAKVSDFGLAK-------------------------------------------KANSQSHDSASGKFPIKWTAPEALRHSQFTTKSDVWSFGILLWEIFSFGRVPYPRIPIQDVVRYIEKGYRMEAPEGCPPEIFKVMNETWALSAQDRPSFGQV 613
BLAST of Tyrosine-protein kinase vs. Ensembl Celegans
Match: csk-1 (Tyrosine-protein kinase csk-1 [Source:UniProtKB/Swiss-Prot;Acc:G5ECJ6]) HSP 1 Score: 318.931 bits (816), Expect = 5.977e-101 Identity = 182/511 (35.62%), Postives = 265/511 (51.86%), Query Frame = 1
Query: 97 GQKAEDLPFSKGEKLKVLKIISDPNWITCSNNKQHQGLVPVNHV--------------------KLSPSLNI--------------EDPWYHGKVSRSLAEERLMPCENGTFLIRSSDKFPGDYTICVKFND-VQFYHVIYSNKGY-TLDEDSWFASMPELIEHYQKDADGLCCTLTK---CYESP-----------------KSRLDYLDENVLNIKFEEIKLGPKIGCGEFSEVLQGEYQDTVVAVKCLKKPINFAEKTLFTFEFSLMAKLNHPHLVTFKGISSSNESVYIITEYMENGSLVNYLRSRGRTVIKTNDQIKFAIDSCSGMCYLEEHCLVHRDLAARNILLNAKLVAKVSDFGLARVDDXXXXXXXXXXXXXXXXXXXXXKTPSPKLMLNVVNDLVSLPTSSVDDNTTSVGRIPVKWTAPEALTHNKYTNKSDVWSFGILLWEIFSFGRTPYPRIYANNVKQHLLNGYRMESPEDTPNDIYELMRDCWALEPEKRPTFCEI 1461
G A D F K + +++L +DP W N Q +GLV + V ++P PW+H +SR E+ L +GTFL+R S FPGD+T+C+ F+ V+ Y + ++ G T D++ +F+++ +L+ HY++DADGLC L C + + R L I +I +G IG GEF +V G Y++ VA+K K+ N +L E M L+HP+LVT G+ + +VY+ITEYM NG+L++ LRSRGR ++ + FA+D C GMCYLE +VHRDLAARN+LL+ LVAKVSDFGLA+ ++ + ++ G+ P+KWTAPEAL H+++T KSDVWSFGILLWEIFSFGR PYPRI +V +++ GYRME+PE P +I+++M + WAL + RP+F ++
Sbjct: 147 GMPARDNVFRKDDHVRILGNTTDPAWYRARNANQEEGLVHADCVVRINGQAYDNGIVRMRASGCDVAPGAASTTSSTSSHHSTAANHQPWFHSMISRENTEKLLRGKPDGTFLVRESTNFPGDFTLCMSFHGKVEHYRIEQTSGGQLTCDKEEYFSNLTQLVSHYKRDADGLCHRLVTPIICETATFSSNGSSSFGSSSTVDLEDRTSVFRHAGLVISSNDIDVGDTIGHGEFGDVRLGTYKNRKVALKVSKRHGNGMLDSLLD-EAKFMVGLSHPNLVTLVGVVLDDVNVYMITEYMANGNLIDLLRSRGRHALERRQLMMFAMDICQGMCYLESKQIVHRDLAARNVLLDDDLVAKVSDFGLAK-------------------------------------------KANSQSHDSASGKFPIKWTAPEALRHSQFTTKSDVWSFGILLWEIFSFGRVPYPRIPIQDVVRYIEKGYRMEAPEGCPPEIFKVMNETWALSAQDRPSFGQV 613
BLAST of Tyrosine-protein kinase vs. Ensembl Celegans
Match: src-2 (Tyrosine protein-kinase src-2 [Source:UniProtKB/Swiss-Prot;Acc:O45539]) HSP 1 Score: 265.388 bits (677), Expect = 1.036e-81 Identity = 164/468 (35.04%), Postives = 244/468 (52.14%), Query Frame = 1
Query: 73 LTALYNFEGQKAEDLPFSKGEKLKVLKIISDPNWITCSNNKQHQGLVPVNHVKLSPSLNIEDPWYHGKVSRSLAEERLMPC--ENGTFLIRSSDKFPGDYTICVKFND-VQFYHV-IYSNKGYTLDEDSWFASMPELIEHYQKDADGLCCTL-TKCY--ESPKSRLDYLDENVLNIKFEEIKLGPKIGCGEFSEVLQGEYQDTV-VAVKCLKKPINFAEKTLFTFEFSLMAKLNHPHLVTFKGISSSNESVYIITEYMENGSLVNYLRSRGRTVIKTNDQIKFAIDSCSGMCYLEEHCLVHRDLAARNILLNAKLVAKVSDFGLARVDDXXXXXXXXXXXXXXXXXXXXXKTPSPKLMLNVVNDLVSLPTSSVDDNTTSVGRIPVKWTAPEALTHNKYTNKSDVWSFGILLWEIFSFGRTPYPRIYANNVKQHLLNGYRMESPEDTPNDIYELMRDCWALEPEKRPTF 1452
AL+ ++ + +DL F K + L++L W G +P N+V S+ + PWY GK+ R AE+ L+ E+G FL+R S+ D ++ V+ ND V+ Y + + GY + FA++ +LI HYQ++ADGLC L C E+P++ D+ + ++L +IG G+F EV +G + V VAVK LK A+ T F E +M KL HP L++ + + +E + I+TE M+ +L+ +L+ RGR + ++ + +GM YLEE +HRDLAARNIL+N L K++DFGLAR+ LM + + R P+KWTAPEA +N++T KSDVWSFGILL EI +FGR PYP + V Q + GYRM P P +Y++M+ CW +P+KRPTF
Sbjct: 62 FVALFQYDARTDDDLSFKKDDILEILNDTQGDWWFARHKATGRTGYIPSNYVAREKSIESQ-PWYFGKMRRIDAEKCLLHTLNEHGAFLVRDSESRQHDLSLSVRENDSVKHYRIRQLDHGGYFIARRRPFATLHDLIAHYQREADGLCVNLGAPCAKSEAPQTTTFTYDDQ-WEVDRRSVRLIRQIGAGQFGEVWEGRWNVNVPVAVKKLKA--GTADPTDFLAEAQIMKKLRHPKLLSLYAVCTRDEPILIVTELMQE-NLLTFLQRRGRQC-QMPQLVEISAQVAAGMAYLEEMNFIHRDLAARNILINNSLSVKIADFGLARI-----------------------------LM------------KENEYEARTGARFPIKWTAPEAANYNRFTTKSDVWSFGILLTEIVTFGRLPYPGMTNAEVLQQVDAGYRMPCPAGCPVTLYDIMQQCWRSDPDKRPTF 482
BLAST of Tyrosine-protein kinase vs. Ensembl Fly
Match: Csk (gene:FBgn0262081 transcript:FBtr0300549) HSP 1 Score: 328.561 bits (841), Expect = 1.794e-103 Identity = 188/438 (42.92%), Postives = 251/438 (57.31%), Query Frame = 1
Query: 217 VNHVKLSPS--------------LNIEDPWYHGKVSRSLAEERLMPCENGTFLIRSSDKFPGDYTICVKFND-VQFYHVIYSNKGYTLDEDSWFASMPELIEHYQKDADGLCCTLTKCYESPK--------SRLDYLDENVLNIKFEEIKLGPKIGCGEFSEVLQGEYQDTVVAVKCLKKPINFAEKTLFTFEFSLMAKLNHPHLVTFKGISSSNESVYIITEYMENGSLVNYLRSRGRTVIKTNDQIKFAIDSCSGMCYLEEHCLVHRDLAARNILLNAKLVAKVSDFGLARVDDXXXXXXXXXXXXXXXXXXXXXKTPSPKLMLNVVNDLVSLPTSSVDDNTTSVGRIPVKWTAPEALTHNKYTNKSDVWSFGILLWEIFSFGRTPYPRIYANNVKQHLLNGYRMESPEDTPNDIYELMRDCWALEPEKRPTFCEI 1461
+NH LSP+ LN PW+HG ++R AE L P E+G FL+R S FPGDYT+CV F V+ Y V Y T+D++ +F ++ +L+ HY+ DADGLC L KC PK + D++D+ + I E++L IG GEF +V+ G ++ VAVK LK + F E S+M L H +LV F G+ +++ +Y++TEYM GSLV+YLRSRGR I DQI FA D+ SGM YLE +VHRDLAARN+L++ VAKVSDFGLAR + N+ D+ LP +KWTAPEAL + +++NKSD+WSFGILLWEI+SFGR PYPRI +V +H+ GY+ME+PE P +IYE+MR W L P KRPTF E+
Sbjct: 327 MNHASLSPTALAPQQGRSRCEVKLNAM-PWFHGSITRDEAEHLLQPREDGLFLVRESTNFPGDYTLCVCFQSKVEHYRVKYLENKLTIDDEEYFENLGQLVAHYEADADGLCTQLIKCL--PKLGKQEFCINSKDFVDKGWV-IPEAELQLRESIGKGEFGDVMLGILRNEKVAVKMLK---DEGAVQKFLAEASVMTTLEHDNLVKFIGLVFTSKHLYLVTEYMSKGSLVDYLRSRGRQHITKKDQIIFAYDTASGMEYLEAKKVVHRDLAARNVLISEDCVAKVSDFGLAREE-----------------------------CYNL--DVGKLP---------------IKWTAPEALKNGRFSNKSDMWSFGILLWEIYSFGRVPYPRIPLADVVKHVEVGYKMEAPEGCPPEIYEMMRQAWDLNPAKRPTFAEL 711
BLAST of Tyrosine-protein kinase vs. Ensembl Fly
Match: Csk (gene:FBgn0262081 transcript:FBtr0300547) HSP 1 Score: 328.561 bits (841), Expect = 1.794e-103 Identity = 188/438 (42.92%), Postives = 251/438 (57.31%), Query Frame = 1
Query: 217 VNHVKLSPS--------------LNIEDPWYHGKVSRSLAEERLMPCENGTFLIRSSDKFPGDYTICVKFND-VQFYHVIYSNKGYTLDEDSWFASMPELIEHYQKDADGLCCTLTKCYESPK--------SRLDYLDENVLNIKFEEIKLGPKIGCGEFSEVLQGEYQDTVVAVKCLKKPINFAEKTLFTFEFSLMAKLNHPHLVTFKGISSSNESVYIITEYMENGSLVNYLRSRGRTVIKTNDQIKFAIDSCSGMCYLEEHCLVHRDLAARNILLNAKLVAKVSDFGLARVDDXXXXXXXXXXXXXXXXXXXXXKTPSPKLMLNVVNDLVSLPTSSVDDNTTSVGRIPVKWTAPEALTHNKYTNKSDVWSFGILLWEIFSFGRTPYPRIYANNVKQHLLNGYRMESPEDTPNDIYELMRDCWALEPEKRPTFCEI 1461
+NH LSP+ LN PW+HG ++R AE L P E+G FL+R S FPGDYT+CV F V+ Y V Y T+D++ +F ++ +L+ HY+ DADGLC L KC PK + D++D+ + I E++L IG GEF +V+ G ++ VAVK LK + F E S+M L H +LV F G+ +++ +Y++TEYM GSLV+YLRSRGR I DQI FA D+ SGM YLE +VHRDLAARN+L++ VAKVSDFGLAR + N+ D+ LP +KWTAPEAL + +++NKSD+WSFGILLWEI+SFGR PYPRI +V +H+ GY+ME+PE P +IYE+MR W L P KRPTF E+
Sbjct: 327 MNHASLSPTALAPQQGRSRCEVKLNAM-PWFHGSITRDEAEHLLQPREDGLFLVRESTNFPGDYTLCVCFQSKVEHYRVKYLENKLTIDDEEYFENLGQLVAHYEADADGLCTQLIKCL--PKLGKQEFCINSKDFVDKGWV-IPEAELQLRESIGKGEFGDVMLGILRNEKVAVKMLK---DEGAVQKFLAEASVMTTLEHDNLVKFIGLVFTSKHLYLVTEYMSKGSLVDYLRSRGRQHITKKDQIIFAYDTASGMEYLEAKKVVHRDLAARNVLISEDCVAKVSDFGLAREE-----------------------------CYNL--DVGKLP---------------IKWTAPEALKNGRFSNKSDMWSFGILLWEIYSFGRVPYPRIPLADVVKHVEVGYKMEAPEGCPPEIYEMMRQAWDLNPAKRPTFAEL 711
BLAST of Tyrosine-protein kinase vs. Ensembl Fly
Match: Csk (gene:FBgn0262081 transcript:FBtr0300548) HSP 1 Score: 328.561 bits (841), Expect = 1.794e-103 Identity = 188/438 (42.92%), Postives = 251/438 (57.31%), Query Frame = 1
Query: 217 VNHVKLSPS--------------LNIEDPWYHGKVSRSLAEERLMPCENGTFLIRSSDKFPGDYTICVKFND-VQFYHVIYSNKGYTLDEDSWFASMPELIEHYQKDADGLCCTLTKCYESPK--------SRLDYLDENVLNIKFEEIKLGPKIGCGEFSEVLQGEYQDTVVAVKCLKKPINFAEKTLFTFEFSLMAKLNHPHLVTFKGISSSNESVYIITEYMENGSLVNYLRSRGRTVIKTNDQIKFAIDSCSGMCYLEEHCLVHRDLAARNILLNAKLVAKVSDFGLARVDDXXXXXXXXXXXXXXXXXXXXXKTPSPKLMLNVVNDLVSLPTSSVDDNTTSVGRIPVKWTAPEALTHNKYTNKSDVWSFGILLWEIFSFGRTPYPRIYANNVKQHLLNGYRMESPEDTPNDIYELMRDCWALEPEKRPTFCEI 1461
+NH LSP+ LN PW+HG ++R AE L P E+G FL+R S FPGDYT+CV F V+ Y V Y T+D++ +F ++ +L+ HY+ DADGLC L KC PK + D++D+ + I E++L IG GEF +V+ G ++ VAVK LK + F E S+M L H +LV F G+ +++ +Y++TEYM GSLV+YLRSRGR I DQI FA D+ SGM YLE +VHRDLAARN+L++ VAKVSDFGLAR + N+ D+ LP +KWTAPEAL + +++NKSD+WSFGILLWEI+SFGR PYPRI +V +H+ GY+ME+PE P +IYE+MR W L P KRPTF E+
Sbjct: 327 MNHASLSPTALAPQQGRSRCEVKLNAM-PWFHGSITRDEAEHLLQPREDGLFLVRESTNFPGDYTLCVCFQSKVEHYRVKYLENKLTIDDEEYFENLGQLVAHYEADADGLCTQLIKCL--PKLGKQEFCINSKDFVDKGWV-IPEAELQLRESIGKGEFGDVMLGILRNEKVAVKMLK---DEGAVQKFLAEASVMTTLEHDNLVKFIGLVFTSKHLYLVTEYMSKGSLVDYLRSRGRQHITKKDQIIFAYDTASGMEYLEAKKVVHRDLAARNVLISEDCVAKVSDFGLAREE-----------------------------CYNL--DVGKLP---------------IKWTAPEALKNGRFSNKSDMWSFGILLWEIYSFGRVPYPRIPLADVVKHVEVGYKMEAPEGCPPEIYEMMRQAWDLNPAKRPTFAEL 711
BLAST of Tyrosine-protein kinase vs. Ensembl Fly
Match: Csk (gene:FBgn0262081 transcript:FBtr0299728) HSP 1 Score: 328.561 bits (841), Expect = 1.794e-103 Identity = 188/438 (42.92%), Postives = 251/438 (57.31%), Query Frame = 1
Query: 217 VNHVKLSPS--------------LNIEDPWYHGKVSRSLAEERLMPCENGTFLIRSSDKFPGDYTICVKFND-VQFYHVIYSNKGYTLDEDSWFASMPELIEHYQKDADGLCCTLTKCYESPK--------SRLDYLDENVLNIKFEEIKLGPKIGCGEFSEVLQGEYQDTVVAVKCLKKPINFAEKTLFTFEFSLMAKLNHPHLVTFKGISSSNESVYIITEYMENGSLVNYLRSRGRTVIKTNDQIKFAIDSCSGMCYLEEHCLVHRDLAARNILLNAKLVAKVSDFGLARVDDXXXXXXXXXXXXXXXXXXXXXKTPSPKLMLNVVNDLVSLPTSSVDDNTTSVGRIPVKWTAPEALTHNKYTNKSDVWSFGILLWEIFSFGRTPYPRIYANNVKQHLLNGYRMESPEDTPNDIYELMRDCWALEPEKRPTFCEI 1461
+NH LSP+ LN PW+HG ++R AE L P E+G FL+R S FPGDYT+CV F V+ Y V Y T+D++ +F ++ +L+ HY+ DADGLC L KC PK + D++D+ + I E++L IG GEF +V+ G ++ VAVK LK + F E S+M L H +LV F G+ +++ +Y++TEYM GSLV+YLRSRGR I DQI FA D+ SGM YLE +VHRDLAARN+L++ VAKVSDFGLAR + N+ D+ LP +KWTAPEAL + +++NKSD+WSFGILLWEI+SFGR PYPRI +V +H+ GY+ME+PE P +IYE+MR W L P KRPTF E+
Sbjct: 327 MNHASLSPTALAPQQGRSRCEVKLNAM-PWFHGSITRDEAEHLLQPREDGLFLVRESTNFPGDYTLCVCFQSKVEHYRVKYLENKLTIDDEEYFENLGQLVAHYEADADGLCTQLIKCL--PKLGKQEFCINSKDFVDKGWV-IPEAELQLRESIGKGEFGDVMLGILRNEKVAVKMLK---DEGAVQKFLAEASVMTTLEHDNLVKFIGLVFTSKHLYLVTEYMSKGSLVDYLRSRGRQHITKKDQIIFAYDTASGMEYLEAKKVVHRDLAARNVLISEDCVAKVSDFGLAREE-----------------------------CYNL--DVGKLP---------------IKWTAPEALKNGRFSNKSDMWSFGILLWEIYSFGRVPYPRIPLADVVKHVEVGYKMEAPEGCPPEIYEMMRQAWDLNPAKRPTFAEL 711
BLAST of Tyrosine-protein kinase vs. Ensembl Fly
Match: Csk (gene:FBgn0262081 transcript:FBtr0300546) HSP 1 Score: 329.331 bits (843), Expect = 6.549e-103 Identity = 188/438 (42.92%), Postives = 251/438 (57.31%), Query Frame = 1
Query: 217 VNHVKLSPS--------------LNIEDPWYHGKVSRSLAEERLMPCENGTFLIRSSDKFPGDYTICVKFND-VQFYHVIYSNKGYTLDEDSWFASMPELIEHYQKDADGLCCTLTKCYESPK--------SRLDYLDENVLNIKFEEIKLGPKIGCGEFSEVLQGEYQDTVVAVKCLKKPINFAEKTLFTFEFSLMAKLNHPHLVTFKGISSSNESVYIITEYMENGSLVNYLRSRGRTVIKTNDQIKFAIDSCSGMCYLEEHCLVHRDLAARNILLNAKLVAKVSDFGLARVDDXXXXXXXXXXXXXXXXXXXXXKTPSPKLMLNVVNDLVSLPTSSVDDNTTSVGRIPVKWTAPEALTHNKYTNKSDVWSFGILLWEIFSFGRTPYPRIYANNVKQHLLNGYRMESPEDTPNDIYELMRDCWALEPEKRPTFCEI 1461
+NH LSP+ LN PW+HG ++R AE L P E+G FL+R S FPGDYT+CV F V+ Y V Y T+D++ +F ++ +L+ HY+ DADGLC L KC PK + D++D+ + I E++L IG GEF +V+ G ++ VAVK LK + F E S+M L H +LV F G+ +++ +Y++TEYM GSLV+YLRSRGR I DQI FA D+ SGM YLE +VHRDLAARN+L++ VAKVSDFGLAR + N+ D+ LP +KWTAPEAL + +++NKSD+WSFGILLWEI+SFGR PYPRI +V +H+ GY+ME+PE P +IYE+MR W L P KRPTF E+
Sbjct: 409 MNHASLSPTALAPQQGRSRCEVKLNAM-PWFHGSITRDEAEHLLQPREDGLFLVRESTNFPGDYTLCVCFQSKVEHYRVKYLENKLTIDDEEYFENLGQLVAHYEADADGLCTQLIKCL--PKLGKQEFCINSKDFVDKGWV-IPEAELQLRESIGKGEFGDVMLGILRNEKVAVKMLK---DEGAVQKFLAEASVMTTLEHDNLVKFIGLVFTSKHLYLVTEYMSKGSLVDYLRSRGRQHITKKDQIIFAYDTASGMEYLEAKKVVHRDLAARNVLISEDCVAKVSDFGLAREE-----------------------------CYNL--DVGKLP---------------IKWTAPEALKNGRFSNKSDMWSFGILLWEIYSFGRVPYPRIPLADVVKHVEVGYKMEAPEGCPPEIYEMMRQAWDLNPAKRPTFAEL 793
BLAST of Tyrosine-protein kinase vs. Ensembl Zebrafish
Match: csk (C-terminal Src kinase [Source:ZFIN;Acc:ZDB-GENE-061103-493]) HSP 1 Score: 358.221 bits (918), Expect = 5.078e-118 Identity = 193/480 (40.21%), Postives = 267/480 (55.62%), Query Frame = 1
Query: 64 GDFLTALYNFEGQKAEDLPFSKGEKLKVLKIISDPNWITCSNNKQHQGLVPVNHVKLSPSLNIED-----PWYHGKVSRSLAEERLMPCENGTFLIRSSDKFPGDYTICVKFND-VQFYHVIYSNKGYTLDEDSWFASMPELIEHYQKDADGLCCTLTK--CYESPKSRLDYLDENVLNIKFEEIKLGPKIGCGEFSEVLQGEYQDTVVAVKCLKKPINFAEKTLFTFEFSLMAKLNHPHLVTFKG-ISSSNESVYIITEYMENGSLVNYLRSRGRTVIKTNDQIKFAIDSCSGMCYLEEHCLVHRDLAARNILLNAKLVAKVSDFGLARVDDXXXXXXXXXXXXXXXXXXXXXKTPSPKLMLNVVNDLVSLPTSSVDDNTTSVGRIPVKWTAPEALTHNKYTNKSDVWSFGILLWEIFSFGRTPYPRIYANNVKQHLLNGYRMESPEDTPNDIYELMRDCWALEPEKRPTFCEIHKILH 1476
G A YNF G +DLP KG+ L ++ + DPNW N+ +G +P N+V+ + PW+HGK++R AE L P E G FL+R S +PGDYT+CV + V+ Y +IY N ++DE+ +F ++ +L+EHY KDADGLC L K E + D + + +E+KL IG GEF +V+ G+Y+ VAVKC+K + A F E S+M +L H +LV G I S+YI+TEYM GSLV+YLRSRGRTVI + I F++D C M YLE + VHRDLAARN+L++ +AKVSDFGL + SS D ++PVKWT+PEAL K++ KSDVWS+GILLWEI+SFGR PYPRI V + GY+M+SP+ P +Y++M+ CW L+ RP+F ++ + L
Sbjct: 11 GTECVARYNFPGTADQDLPMCKGDVLTIVGVTKDPNWYRAKNSAGREGTIPANYVQKREGVKSASKLSLMPWFHGKITREQAERLLYPPETGLFLVRESTNYPGDYTLCVSCDGKVEHYRIIYHNGKLSIDEEEYFENLMQLMEHYTKDADGLCTRLIKPKIMEGTVAAQDEFSRSGWALNRKELKLIQTIGKGEFGDVMVGDYRGKKVAVKCIK---HDATAQAFVAEASVMTQLRHNNLVQLLGVIVEEKGSLYIVTEYMAKGSLVDYLRSRGRTVIGGDRLINFSMDVCKAMEYLEANNFVHRDLAARNVLVSEDNIAKVSDFGLTK------------------------------------------EASSTQDT----AKLPVKWTSPEALREKKFSTKSDVWSYGILLWEIYSFGRVPYPRIPLKEVVPRVEKGYKMDSPDGCPPVVYDIMKQCWTLDAVVRPSFRDLREKLQ 441
BLAST of Tyrosine-protein kinase vs. Ensembl Zebrafish
Match: matk (megakaryocyte-associated tyrosine kinase [Source:ZFIN;Acc:ZDB-GENE-070705-183]) HSP 1 Score: 297.745 bits (761), Expect = 9.480e-95 Identity = 169/470 (35.96%), Postives = 259/470 (55.11%), Query Frame = 1
Query: 103 KAEDLPFSKGEKLKVLKIISDPNWITCSNNKQHQGLVPVNHVKLSPSLNIED-----PWYHGKVSRSLAEERLMPCENGTFLIRSSDKFPGDYTICVKFNDVQF-YHVIYSNKGYTLDEDSWFASMPELIEHYQKDADGLCCTLTK--CYESPKSRLDYLDENVLNIKFEEIKLGPKIGCGEFSEVLQGEYQDTVVAVKCLKKPINFAEKTLFTFEFSLMAKLNHPHLVTFKGISSSNESVYIITEYMENGSLVNYLRSRGRTVIKTNDQIKFAIDSCSGMCYLEEHCLVHRDLAARNILLNAKLVAKVSDFGLARVDDXXXXXXXXXXXXXXXXXXXXXKTPSPKLMLNVVNDLVSLPTSSVDDNTTSVGRIPVKWTAPEALTHNKYTNKSDVWSFGILLWEIFSFGRTPYPRIYANNVKQHLLNGYRMESPEDTPNDIYELMRDCWALEPEKRPTFCEIHKILHKKMK 1488
K ++ + KG+ +L ++ + N +G V ++++ +L I+ PW+HGK++ A ++L P E+G FL+R S + PGD+ +CV F+ F Y VIY + T+D +F ++ ++IE Y ++ + L K E KS L ++ + ++ LG IG GEF V GEY VAVK +K + F E S+M L+H +LV G+ N ++I+TE M G+LVN+LRSRGR + ++FA+D C GM +LE L+HRDLA RNIL++ VAK+SDFGLARV + +VD++ ++PVKWTAPEAL + K++ +SDVWS+G+LLWEIFS+GR PYP++ N VK+ + GYRM+ P++ P D+Y +M CW EP+KRP+F ++ + L K++K
Sbjct: 25 KDGEISYHKGD---ILTLVGKGEYTARHNTTGEEGQVSGSNLREREALRIDPKLSLMPWFHGKIAGQQAVDKLKPTEDGLFLVRESVRHPGDFVLCVCFSQKVFHYRVIYQDNKLTIDNMQFFDNLIDMIEFYSRNRGAIATLLLKPKKKEGLKSAETKLLKSGWLLDLSKLTLGEIIGEGEFGAVFAGEYTGQRVAVKIIKCDVT---AQAFLEETSVMTNLHHKNLVPLLGVILHN-GLHIVTELMTKGNLVNFLRSRGRFAVSVIQLLRFALDVCEGMEHLESKKLLHRDLAGRNILVSEDGVAKISDFGLARVG-----------------------------------------SMAVDNS-----KLPVKWTAPEALKNKKFSTQSDVWSYGVLLWEIFSYGRQPYPKMTVNEVKECVEKGYRMDPPDECPADVYSIMTSCWQTEPKKRPSFHKLRERLEKELK 441
BLAST of Tyrosine-protein kinase vs. Ensembl Zebrafish
Match: matk (megakaryocyte-associated tyrosine kinase [Source:ZFIN;Acc:ZDB-GENE-070705-183]) HSP 1 Score: 295.819 bits (756), Expect = 4.701e-94 Identity = 168/459 (36.60%), Postives = 253/459 (55.12%), Query Frame = 1
Query: 121 FSKGEKLKVLKIISDPNWITCSNNKQHQGLVPVNHVKLSPSLNIEDPWYHGKVSRSLAEERLMPCENGTFLIRSSDKFPGDYTICVKFNDVQF-YHVIYSNKGYTLDEDSWFASMPELIEHYQKDADGLCCTLTK--CYESPKSRLDYLDENVLNIKFEEIKLGPKIGCGEFSEVLQGEYQDTVVAVKCLKKPINFAEKTLFTFEFSLMAKLNHPHLVTFKGISSSNESVYIITEYMENGSLVNYLRSRGRTVIKTNDQIKFAIDSCSGMCYLEEHCLVHRDLAARNILLNAKLVAKVSDFGLARVDDXXXXXXXXXXXXXXXXXXXXXKTPSPKLMLNVVNDLVSLPTSSVDDNTTSVGRIPVKWTAPEALTHNKYTNKSDVWSFGILLWEIFSFGRTPYPRIYANNVKQHLLNGYRMESPEDTPNDIYELMRDCWALEPEKRPTFCEIHKILHKKMK 1488
KGE + ++ SN ++ + L ++ P L++ PW+HGK++ A ++L P E+G FL+R S + PGD+ +CV F+ F Y VIY + T+D +F ++ ++IE Y ++ + L K E KS L ++ + ++ LG IG GEF V GEY VAVK +K + F E S+M L+H +LV G+ N ++I+TE M G+LVN+LRSRGR + ++FA+D C GM +LE L+HRDLA RNIL++ VAK+SDFGLARV + +VD++ ++PVKWTAPEAL + K++ +SDVWS+G+LLWEIFS+GR PYP++ N VK+ + GYRM+ P++ P D+Y +M CW EP+KRP+F ++ + L K++K
Sbjct: 37 MRKGEYTARHNTTGEEGQVSGSNLREREAL------RIDPKLSLM-PWFHGKIAGQQAVDKLKPTEDGLFLVRESVRHPGDFVLCVCFSQKVFHYRVIYQDNKLTIDNMQFFDNLIDMIEFYSRNRGAIATLLLKPKKKEGLKSAETKLLKSGWLLDLSKLTLGEIIGEGEFGAVFAGEYTGQRVAVKIIKCDVT---AQAFLEETSVMTNLHHKNLVPLLGVILHN-GLHIVTELMTKGNLVNFLRSRGRFAVSVIQLLRFALDVCEGMEHLESKKLLHRDLAGRNILVSEDGVAKISDFGLARVG-----------------------------------------SMAVDNS-----KLPVKWTAPEALKNKKFSTQSDVWSYGVLLWEIFSYGRQPYPKMTVNEVKECVEKGYRMDPPDECPADVYSIMTSCWQTEPKKRPSFHKLRERLEKELK 438
BLAST of Tyrosine-protein kinase vs. Ensembl Zebrafish
Match: lyn (LYN proto-oncogene, Src family tyrosine kinase [Source:ZFIN;Acc:ZDB-GENE-040912-7]) HSP 1 Score: 282.337 bits (721), Expect = 5.305e-88 Identity = 166/480 (34.58%), Postives = 254/480 (52.92%), Query Frame = 1
Query: 70 FLTALYNFEGQKAEDLPFSKGEKLKVLKIISDPNWITCSNNKQHQGLVPVNHVKLSPSLNIEDPWYHGKVSRSLAEERLMPCEN--GTFLIRSSDKFPGDYTICVKFNDVQFYHVI-------YSNKGYTLDEDSWFASMPELIEHYQKDADGLCCTLTKCYESPKSRLDYLDENVLNIKFEEIKLGPKIGCGEFSEVLQGEYQD-TVVAVKCLKKPINFAEKTLFTFEFSLMAKLNHPHLVTFKGISSSNESVYIITEYMENGSLVNYLRSRGRTVIKTNDQIKFAIDSCSGMCYLEEHCLVHRDLAARNILLNAKLVAKVSDFGLARVDDXXXXXXXXXXXXXXXXXXXXXKTPSPKLMLNVVNDLVSLPTSSVDDNTTSV--GRIPVKWTAPEALTHNKYTNKSDVWSFGILLWEIFSFGRTPYPRIYANNVKQHLLNGYRMESPEDTPNDIYELMRDCWALEPEKRPTFCEIHKIL 1473
+ ALY +E A+DL F KGEKLK+++ + W S + +G +P N+V + ++ E+ W++ ++R AE +L+ N G++LIR S+ G Y++ ++ D Q V+ N GY + F+ + +I+HY K +DGLC L K E PK++ + D++ I + IK+ K+G G+F EV Y + T VAVK LK E F E +LM L H LV + + E +YIITEYM NGSL+++L+S+ + I+ I F+ GM Y+E+ +HRDL A N+L++ L+ K++DFGLARV + DD T+ + P+KWTAPEA+ + +T KSD+WSFG+LL+EI ++G+ PYP + + V + GYRM PE+ P ++YE+M CW +PE RPTF I +L
Sbjct: 65 IVVALYPYEAIHADDLGFKKGEKLKIIEEHGE-WWKARSLTTRKEGFIPSNYVAEADTMETEE-WFYKDITRKDAERQLLAPANKPGSYLIRESETSKGSYSLSIRDVDAQGQDVVKHYKIRSLDNGGYYISPKITFSDISSMIKHYHKQSDGLCRKLDKACEKPKAQKPW-DKDAWEISKDSIKMVKKLGAGQFGEVWMAFYNNSTKVAVKTLKPGTMSVE--AFLEEANLMKTLQHDRLVRLYAVVTKTEPIYIITEYMANGSLLDFLKSQAGSKIQLPKLIDFSAQIAEGMAYIEKKNYIHRDLRAANVLVSEMLLCKIADFGLARVIE--------------------------------------------DDQYTAREGAKFPIKWTAPEAINYGSFTIKSDMWSFGVLLYEIITYGKIPYPGMSNSEVMSSVQRGYRMPRPENCPVELYEIMTTCWKNKPEDRPTFDYIQSVL 495
BLAST of Tyrosine-protein kinase vs. Ensembl Zebrafish
Match: frk (fyn-related Src family tyrosine kinase [Source:ZFIN;Acc:ZDB-GENE-110411-7]) HSP 1 Score: 276.174 bits (705), Expect = 1.284e-85 Identity = 183/489 (37.42%), Postives = 255/489 (52.15%), Query Frame = 1
Query: 79 ALYNFEGQKAEDLPFSKGEKLKVLKIISDPNW------ITCSNNKQHQGLVPVNHVKLSPSLNIEDPWYHGKVSRSLAEERLMPCEN--GTFLIRSSDKFPGDYTICVKFNDVQFYHVI---YSNKGYTLDEDSWFASMPELIEHYQKDADGLCCTLTK-CYESPKSRLDYLDENVLN---IKFEEIKLGPKIGCGEFSEVLQGEYQDTV-VAVKCLKKPINFAEKTLFTFEFSLMAKLNHPHLVTFKGISSSNESVYIITEYMENGSLVNYLRSRGRTVIKTNDQIKFAIDSCSGMCYLEEHCLVHRDLAARNILLNAKLVAKVSDFGLARVDDXXXXXXXXXXXXXXXXXXXXXKTPSPKLMLNVVNDLVSLPTSSVDDNTTSVGRIPVKWTAPEALTHNKYTNKSDVWSFGILLWEIFSFGRTPYPRIYANNVKQHLLNGYRMESPEDTPNDIYELMRDCWALEPEKRPTFCEIHKILHKKMKSFL 1497
ALY++ + +DL F+ G+KL+ I +W S NK+ G +P N+V SL+ E PWY + RS AE+ L+ EN G FLIR+ + PG+ ++ V+ +DV+ H N GY L F ++ EL+EHY K DGLC L + C +S L N ++ I+ +KL ++G G+F EV +G + DT VAVK LK P N K F E +M KL H L+ + + E +YIITE M NGSL+ YL++ ++ +DQI SGM YLE +HRDLAARN+L+ V KV+DFGLARV ++ +++ + + PVKWTAPEA+ NK+T KSDVWSFGILL+EI +FG+TPYP + V Q L GYRM SP + +Y++M DCW P RPTF + L K++ F
Sbjct: 59 ALYDYTARTDDDLSFNAGDKLE--PITKGEDWWFSKAITGISANKK--GYIPANYVAPVESLDAE-PWYFPETKRSDAEKMLISQENKKGAFLIRNCESQPGELSLSVR-DDVKVKHYKIRKLDNGGYYLSTARNFPTLRELVEHYSKHEDGLCVRLAEPCKKSVAPETHGLSYNTVDQWEIERSSVKLLKQLGAGQFGEVFEGLWNDTTPVAVKTLK-PGNMDPKD-FLREAQIMKKLRHSKLIQLYAVCTLEEPIYIITELMSNGSLLEYLQNDRGATLRMSDQIDMGAQVASGMAYLELQNYIHRDLAARNVLVGDNNVCKVADFGLARV-----------------------------FQMDNEDNVYEAKEGT---------KFPVKWTAPEAINENKFTIKSDVWSFGILLYEIVTFGQTPYPTMTNFQVVQQLPKGYRMSSPPNCHKCLYDIMLDCWKDVPADRPTF----ETLQWKLEDFF 497
BLAST of Tyrosine-protein kinase vs. Ensembl Xenopus
Match: csk (C-terminal Src kinase [Source:NCBI gene;Acc:100216174]) HSP 1 Score: 365.155 bits (936), Expect = 1.658e-120 Identity = 196/492 (39.84%), Postives = 279/492 (56.71%), Query Frame = 1
Query: 52 PLKPGDFLTALYNFEGQKAEDLPFSKGEKLKVLKIISDPNWITCSNNKQHQGLVPVNHVKLSPSLNIED-----PWYHGKVSRSLAEERLMPCENGTFLIRSSDKFPGDYTICVKF-NDVQFYHVIYSNKGYTLDEDSWFASMPELIEHYQKDADGLCCTLTK--CYESPKSRLDYLDENVLNIKFEEIKLGPKIGCGEFSEVLQGEYQDTVVAVKCLKKPINFAEKTLFTFEFSLMAKLNHPHLVTFKGISSSNES-VYIITEYMENGSLVNYLRSRGRTVIKTNDQIKFAIDSCSGMCYLEEHCLVHRDLAARNILLNAKLVAKVSDFGLARVDDXXXXXXXXXXXXXXXXXXXXXKTPSPKLMLNVVNDLVSLPTSSVDDNTTSVGRIPVKWTAPEALTHNKYTNKSDVWSFGILLWEIFSFGRTPYPRIYANNVKQHLLNGYRMESPEDTPNDIYELMRDCWALEPEKRPTFCEIHKIL-HKKMKSFL 1497
P + G A Y+F+G+ +DL FSKGE L ++ + DPNW N G +P N+V+ + PW+HGK++R AE L P E G FL+R S +PGDYT+CV V+ Y +IYS+ ++DE+ +F ++ +L+EHY DADGLC L K E + D + +K ++KL IG GEF +V+ GE+Q VAVKC+K N A F E +M +L H +LV G+ ++S ++I+TE+M GSLV+YLRSRGR+V+ +KF++D GM YLE + VHRDLAARN+L++ + +AKVSDFGL + S++ D + ++PVKWTAPEAL ++ KSDVWSFGILLWEI+SFGR PYPRI +V + NGY+M++P+ P +Y+LM+ CW L+P++RPTF + + L H K K
Sbjct: 13 PWQAGTECIANYDFQGKAEQDLHFSKGEVLTIVAVTKDPNWYKAKNKVGRVGFIPANYVQKREGVKSGTKLSLMPWFHGKITREQAERLLYPPETGLFLVRESTNYPGDYTLCVSCEGKVEHYRIIYSSGKLSIDEEEYFENLMQLVEHYTNDADGLCTNLMKPKLVEGTVAAQDEFSRSGWALKMRDLKLLHTIGKGEFGDVMLGEHQGVKVAVKCIK---NDATAQAFVAEAMVMTQLQHNNLVQLLGVIVEDKSGLFIVTEFMAKGSLVDYLRSRGRSVLGGECLLKFSLDVSEGMAYLESNNFVHRDLAARNVLVSEENIAKVSDFGLTK------------------------------------------EASAIQDTS----KLPVKWTAPEALRDKLFSTKSDVWSFGILLWEIYSFGRVPYPRIALKDVVPKVENGYKMDAPDGCPPVVYDLMKQCWHLDPKQRPTFRNLREQLEHIKAKELF 455
BLAST of Tyrosine-protein kinase vs. Ensembl Xenopus
Match: csk (C-terminal Src kinase [Source:NCBI gene;Acc:100216174]) HSP 1 Score: 362.073 bits (928), Expect = 2.239e-119 Identity = 196/498 (39.36%), Postives = 281/498 (56.43%), Query Frame = 1
Query: 40 LLHMPLKPGDFLTALYNFEGQKAEDLPFSKGEKLKVLKIISDPNWITCSNNKQHQGLVPVNHVKLSPSLNIED-----PWYHGKVSRSLAEERLMPCENGTFLIRSSDKFPGDYTICVKF-NDVQFYHVIYSNKGYTLDEDSWFASMPELIEHYQKDADGLCCTLTK--CYESPKSRLDYLDENVLNIKFEEIKLGPKIGCGEFSEVLQGEYQDTVVAVKCLKKPINFAEKTLFTFEFSLMAKLNHPHLVTFKGISSSNES-VYIITEYMENGSLVNYLRSRGRTVIKTNDQIKFAIDSCSGMCYLEEHCLVHRDLAARNILLNAKLVAKVSDFGLARVDDXXXXXXXXXXXXXXXXXXXXXKTPSPKLMLNVVNDLVSLPTSSVDDNTTSVGRIPVKWTAPEALTHNK--YTNKSDVWSFGILLWEIFSFGRTPYPRIYANNVKQHLLNGYRMESPEDTPNDIYELMRDCWALEPEKRPTFCEIHKIL-HKKMKSFL 1497
++ P + G A Y+F+G+ +DL FSKGE L ++ + DPNW N G +P N+V+ + PW+HGK++R AE L P E G FL+R S +PGDYT+CV V+ Y +IYS+ ++DE+ +F ++ +L+EHY DADGLC L K E + D + +K ++KL IG GEF +V+ GE+Q VAVKC+K N A F E +M +L H +LV G+ ++S ++I+TE+M GSLV+YLRSRGR+V+ +KF++D GM YLE + VHRDLAARN+L++ + +AKVSDFGL + S++ D + ++PVKWTAPEAL ++ KSDVWSFGILLWEI+SFGR PYPRI +V + NGY+M++P+ P +Y+LM+ CW L+P++RPTF + + L H K K
Sbjct: 3 VVQAPWQAGTECIANYDFQGKAEQDLHFSKGEVLTIVAVTKDPNWYKAKNKVGRVGFIPANYVQKREGVKSGTKLSLMPWFHGKITREQAERLLYPPETGLFLVRESTNYPGDYTLCVSCEGKVEHYRIIYSSGKLSIDEEEYFENLMQLVEHYTNDADGLCTNLMKPKLVEGTVAAQDEFSRSGWALKMRDLKLLHTIGKGEFGDVMLGEHQGVKVAVKCIK---NDATAQAFVAEAMVMTQLQHNNLVQLLGVIVEDKSGLFIVTEFMAKGSLVDYLRSRGRSVLGGECLLKFSLDVSEGMAYLESNNFVHRDLAARNVLVSEENIAKVSDFGLTK------------------------------------------EASAIQDTS----KLPVKWTAPEALRDKASLFSTKSDVWSFGILLWEIYSFGRVPYPRIALKDVVPKVENGYKMDAPDGCPPVVYDLMKQCWHLDPKQRPTFRNLREQLEHIKAKELF 451
BLAST of Tyrosine-protein kinase vs. Ensembl Xenopus
Match: csk (C-terminal Src kinase [Source:NCBI gene;Acc:100216174]) HSP 1 Score: 340.887 bits (873), Expect = 9.647e-112 Identity = 182/460 (39.57%), Postives = 260/460 (56.52%), Query Frame = 1
Query: 148 LKIISDPNWITCSNNKQHQGLVPVNHVKLSPSLNIED-----PWYHGKVSRSLAEERLMPCENGTFLIRSSDKFPGDYTICVKF-NDVQFYHVIYSNKGYTLDEDSWFASMPELIEHYQKDADGLCCTLTK--CYESPKSRLDYLDENVLNIKFEEIKLGPKIGCGEFSEVLQGEYQDTVVAVKCLKKPINFAEKTLFTFEFSLMAKLNHPHLVTFKGISSSNES-VYIITEYMENGSLVNYLRSRGRTVIKTNDQIKFAIDSCSGMCYLEEHCLVHRDLAARNILLNAKLVAKVSDFGLARVDDXXXXXXXXXXXXXXXXXXXXXKTPSPKLMLNVVNDLVSLPTSSVDDNTTSVGRIPVKWTAPEALTHNKYTNKSDVWSFGILLWEIFSFGRTPYPRIYANNVKQHLLNGYRMESPEDTPNDIYELMRDCWALEPEKRPTFCEIHKIL-HKKMKSFL 1497
+ ++ DPNW N G +P N+V+ + PW+HGK++R AE L P E G FL+R S +PGDYT+CV V+ Y +IYS+ ++DE+ +F ++ +L+EHY DADGLC L K E + D + +K ++KL IG GEF +V+ GE+Q VAVKC+K N A F E +M +L H +LV G+ ++S ++I+TE+M GSLV+YLRSRGR+V+ +KF++D GM YLE + VHRDLAARN+L++ + +AKVSDFGL + S++ D + ++PVKWTAPEAL ++ KSDVWSFGILLWEI+SFGR PYPRI +V + NGY+M++P+ P +Y+LM+ CW L+P++RPTF + + L H K K
Sbjct: 1 MSVVQDPNWYKAKNKVGRVGFIPANYVQKREGVKSGTKLSLMPWFHGKITREQAERLLYPPETGLFLVRESTNYPGDYTLCVSCEGKVEHYRIIYSSGKLSIDEEEYFENLMQLVEHYTNDADGLCTNLMKPKLVEGTVAAQDEFSRSGWALKMRDLKLLHTIGKGEFGDVMLGEHQGVKVAVKCIK---NDATAQAFVAEAMVMTQLQHNNLVQLLGVIVEDKSGLFIVTEFMAKGSLVDYLRSRGRSVLGGECLLKFSLDVSEGMAYLESNNFVHRDLAARNVLVSEENIAKVSDFGLTK------------------------------------------EASAIQDTS----KLPVKWTAPEALRDKLFSTKSDVWSFGILLWEIYSFGRVPYPRIALKDVVPKVENGYKMDAPDGCPPVVYDLMKQCWHLDPKQRPTFRNLREQLEHIKAKELF 411
BLAST of Tyrosine-protein kinase vs. Ensembl Xenopus
Match: csk (C-terminal Src kinase [Source:NCBI gene;Acc:100216174]) HSP 1 Score: 301.982 bits (772), Expect = 2.710e-96 Identity = 177/496 (35.69%), Postives = 264/496 (53.23%), Query Frame = 1
Query: 40 LLHMPLKPGDFLTALYNFEGQKAEDLPFSKGEKLKVLKIISDPNWITCSNNKQHQGLVPVNHVKLSPSLNIED-----PWYHGKVSRSLAEERLMPCENGTFLIRSSDKFPGDYTICVKF-NDVQFYHVIYSNKGYTLDEDSWFASMPELIEHYQKDADGLCCTLTK--CYESPKSRLDYLDENVLNIKFEEIKLGPKIGCGEFSEVLQGEYQDTVVAVKCLKKPINFAEKTLFTFEFSLMAKLNHPHLVTFKGISSSNES-VYIITEYMENGSLVNYLRSRGRTVIKTNDQIKFAIDSCSGMCYLEEHCLVHRDLAARNILLNAKLVAKVSDFGLARVDDXXXXXXXXXXXXXXXXXXXXXKTPSPKLMLNVVNDLVSLPTSSVDDNTTSVGRIPVKWTAPEALTHNKYTNKSDVWSFGILLWEIFSFGRTPYPRIYANNVKQHLLNGYRMESPEDTPNDIYELMRDCWALEPEKRPTFCEIHKIL-HKKMKSFL 1497
++ P + G A Y+F+G+ +DL FSKGE L ++ + DPNW N G +P N+V+ + PW+HGK++R AE L P E G FL+R S +PGDYT+CV V+ Y +IYS+ ++DE+ +F ++ +L+EHY DADGLC L K E + D + +K ++KL IG GEF +V+ GE+Q VAVKC+K N A F E +M +L H +LV G+ ++S ++I+TE+M GSLV+YLRSRGR+V+ +KF++D GM YLE + VHRDLAARN+L++ + +AKVSDFGL + S++ D + ++PVKWTAPEAL +K+ V ++ S R + +V + NGY+M++P+ P +Y+LM+ CW L+P++RPTF + + L H K K
Sbjct: 3 VVQAPWQAGTECIANYDFQGKAEQDLHFSKGEVLTIVAVTKDPNWYKAKNKVGRVGFIPANYVQKREGVKSGTKLSLMPWFHGKITREQAERLLYPPETGLFLVRESTNYPGDYTLCVSCEGKVEHYRIIYSSGKLSIDEEEYFENLMQLVEHYTNDADGLCTNLMKPKLVEGTVAAQDEFSRSGWALKMRDLKLLHTIGKGEFGDVMLGEHQGVKVAVKCIK---NDATAQAFVAEAMVMTQLQHNNLVQLLGVIVEDKSGLFIVTEFMAKGSLVDYLRSRGRSVLGGECLLKFSLDVSEGMAYLESNNFVHRDLAARNVLVSEENIAKVSDFGLTK------------------------------------------EASAIQDTS----KLPVKWTAPEAL-----RDKASV--------KLPSITRQSTRAL--KDVVPKVENGYKMDAPDGCPPVVYDLMKQCWHLDPKQRPTFRNLREQLEHIKAKELF 434
BLAST of Tyrosine-protein kinase vs. Ensembl Xenopus
Match: gpn2 (GPN-loop GTPase 2 [Source:Xenbase;Acc:XB-GENE-5751862]) HSP 1 Score: 288.115 bits (736), Expect = 1.602e-90 Identity = 168/460 (36.52%), Postives = 247/460 (53.70%), Query Frame = 1
Query: 103 KAEDLPFSKGEKLKVLKIISDPNWITCSNNKQ-HQGLVPVNHVKLSPSLNIED-----PWYHGKVSRSLAEERLMPCENGTFLIRSSDKFPGDYTICVKFNDVQFYHVIYSNKGYTLDED--SWFASMPELIEHYQKDADGLCCTLTK--CYESPKSRLDYLDENVLNIKFEEIKLGPKIGCGEFSEVLQGEYQDTVVAVKCLKKPINFAEKTLFTFEFSLMAKLNHPHLVTFKGISSSNESVYIITEYMENGSLVNYLRSRGRTVIKTNDQIKFAIDSCSGMCYLEEHCLVHRDLAARNILLNAKLVAKVSDFGLARVDDXXXXXXXXXXXXXXXXXXXXXKTPSPKLMLNVVNDLVSLPTSSVDDNTTSVGRIPVKWTAPEALTHNKYTNKSDVWSFGILLWEIFSFGRTPYPRIYANNVKQHLLNGYRMESPEDTPNDIYELMRDCWALEPEKRPTF 1452
K ++L F KG+ + ++ + W ++ +GL+ V+ P + ++ PW+HG ++ A ++L P ENG FL+R S + PGDY +CV F D + H SN+G L+ D F ++ ++IE+Y L L K C + S L + + F+ + LG KIG GEF +VLQGEY VA+K +K + F E + M KL H +LV G+ N + ++ E M G+LVNYLRSRGR+++ + F++D GM YLE LVHRDLAARNIL++ K AK+SDFGL++ P DD + R+P+KWTAPEAL + K++++SDVWSFG+LLWE++S+GR PYP++ V + + GYRME+PE+ P IY +M+ CW +P KRPTF
Sbjct: 21 KPKELAFHKGDLVTIVSTCQEKGWYYAHHDGSGMEGLIWSGAVRERPPIKVDAKLSVMPWFHGAITGVQAVQQLQPKENGLFLVRESVRHPGDYVLCVCFKD-EVTHYRISNQGGKLNIDLTQNFNNLMDMIEYYSAHQGVLTTRLIKPKCKQGMISAEQKLAKAGWLLNFQNLTLGKKIGEGEFGDVLQGEYMGRPVAIKNIKCDMTAQN---FLSETATMTKLQHKNLVNLLGVILKN-GLLLVMELMSKGNLVNYLRSRGRSMVPPYQLLIFSMDIVQGMEYLELKRLVHRDLAARNILVSEKGEAKISDFGLSK------------------------------------------PQLQQDD----LSRLPIKWTAPEALQNYKFSSRSDVWSFGVLLWEVYSYGRAPYPKMSVREVIEAVKKGYRMEAPENCPPMIYSIMKSCWEADPGKRPTF 429
BLAST of Tyrosine-protein kinase vs. Ensembl Mouse
Match: Csk (c-src tyrosine kinase [Source:MGI Symbol;Acc:MGI:88537]) HSP 1 Score: 362.844 bits (930), Expect = 9.079e-120 Identity = 193/474 (40.72%), Postives = 267/474 (56.33%), Query Frame = 1
Query: 79 ALYNFEGQKAEDLPFSKGEKLKVLKIISDPNWITCSNNKQHQGLVPVNHVKLSPSLNIED-----PWYHGKVSRSLAEERLMPCENGTFLIRSSDKFPGDYTICVKF-NDVQFYHVIYSNKGYTLDEDSWFASMPELIEHYQKDADGLCCTLTK--CYESPKSRLDYLDENVLNIKFEEIKLGPKIGCGEFSEVLQGEYQDTVVAVKCLKKPINFAEKTLFTFEFSLMAKLNHPHLVTFKG-ISSSNESVYIITEYMENGSLVNYLRSRGRTVIKTNDQIKFAIDSCSGMCYLEEHCLVHRDLAARNILLNAKLVAKVSDFGLARVDDXXXXXXXXXXXXXXXXXXXXXKTPSPKLMLNVVNDLVSLPTSSVDDNTTSVGRIPVKWTAPEALTHNKYTNKSDVWSFGILLWEIFSFGRTPYPRIYANNVKQHLLNGYRMESPEDTPNDIYELMRDCWALEPEKRPTFCEIHKIL 1473
A YNF G +DLPF KG+ L ++ + DPNW N +G++P N+V+ + PW+HGK++R AE L P E G FL+R S +PGDYT+CV V+ Y ++Y ++DE+ +F ++ +L+EHY DADGLC L K E + D + + +E+KL IG GEF +V+ G+Y+ VAVKC+K N A F E S+M +L H +LV G I +YI+TEYM GSLV+YLRSRGR+V+ + +KF++D C M YLE + VHRDLAARN+L++ VAKVSDFGL + SS D G++PVKWTAPEAL K++ KSDVWSFGILLWEI+SFGR PYPRI +V + GY+M++P+ P +YE+M++CW L+ RPTF ++ + L
Sbjct: 16 AKYNFHGTAEQDLPFCKGDVLTIVAVTKDPNWYKAKNKVGREGIIPANYVQKREGVKAGTKLSLMPWFHGKITREQAERLLYPPETGLFLVRESTNYPGDYTLCVSCEGKVEHYRIMYHASKLSIDEEVYFENLMQLVEHYTTDADGLCTRLIKPKVMEGTVAAQDEFYRSGWALNMKELKLLQTIGKGEFGDVMLGDYRGNKVAVKCIK---NDATAQAFLAEASVMTQLRHSNLVQLLGVIVEEKGGLYIVTEYMAKGSLVDYLRSRGRSVLGGDCLLKFSLDVCEAMEYLEGNNFVHRDLAARNVLVSEDNVAKVSDFGLTK------------------------------------------EASSTQDT----GKLPVKWTAPEALREKKFSTKSDVWSFGILLWEIYSFGRVPYPRIPLKDVVPRVEKGYKMDAPDGCPPAVYEVMKNCWHLDAATRPTFLQLREQL 440
BLAST of Tyrosine-protein kinase vs. Ensembl Mouse
Match: Csk (c-src tyrosine kinase [Source:MGI Symbol;Acc:MGI:88537]) HSP 1 Score: 362.844 bits (930), Expect = 9.079e-120 Identity = 193/474 (40.72%), Postives = 267/474 (56.33%), Query Frame = 1
Query: 79 ALYNFEGQKAEDLPFSKGEKLKVLKIISDPNWITCSNNKQHQGLVPVNHVKLSPSLNIED-----PWYHGKVSRSLAEERLMPCENGTFLIRSSDKFPGDYTICVKF-NDVQFYHVIYSNKGYTLDEDSWFASMPELIEHYQKDADGLCCTLTK--CYESPKSRLDYLDENVLNIKFEEIKLGPKIGCGEFSEVLQGEYQDTVVAVKCLKKPINFAEKTLFTFEFSLMAKLNHPHLVTFKG-ISSSNESVYIITEYMENGSLVNYLRSRGRTVIKTNDQIKFAIDSCSGMCYLEEHCLVHRDLAARNILLNAKLVAKVSDFGLARVDDXXXXXXXXXXXXXXXXXXXXXKTPSPKLMLNVVNDLVSLPTSSVDDNTTSVGRIPVKWTAPEALTHNKYTNKSDVWSFGILLWEIFSFGRTPYPRIYANNVKQHLLNGYRMESPEDTPNDIYELMRDCWALEPEKRPTFCEIHKIL 1473
A YNF G +DLPF KG+ L ++ + DPNW N +G++P N+V+ + PW+HGK++R AE L P E G FL+R S +PGDYT+CV V+ Y ++Y ++DE+ +F ++ +L+EHY DADGLC L K E + D + + +E+KL IG GEF +V+ G+Y+ VAVKC+K N A F E S+M +L H +LV G I +YI+TEYM GSLV+YLRSRGR+V+ + +KF++D C M YLE + VHRDLAARN+L++ VAKVSDFGL + SS D G++PVKWTAPEAL K++ KSDVWSFGILLWEI+SFGR PYPRI +V + GY+M++P+ P +YE+M++CW L+ RPTF ++ + L
Sbjct: 16 AKYNFHGTAEQDLPFCKGDVLTIVAVTKDPNWYKAKNKVGREGIIPANYVQKREGVKAGTKLSLMPWFHGKITREQAERLLYPPETGLFLVRESTNYPGDYTLCVSCEGKVEHYRIMYHASKLSIDEEVYFENLMQLVEHYTTDADGLCTRLIKPKVMEGTVAAQDEFYRSGWALNMKELKLLQTIGKGEFGDVMLGDYRGNKVAVKCIK---NDATAQAFLAEASVMTQLRHSNLVQLLGVIVEEKGGLYIVTEYMAKGSLVDYLRSRGRSVLGGDCLLKFSLDVCEAMEYLEGNNFVHRDLAARNVLVSEDNVAKVSDFGLTK------------------------------------------EASSTQDT----GKLPVKWTAPEALREKKFSTKSDVWSFGILLWEIYSFGRVPYPRIPLKDVVPRVEKGYKMDAPDGCPPAVYEVMKNCWHLDAATRPTFLQLREQL 440
BLAST of Tyrosine-protein kinase vs. Ensembl Mouse
Match: Csk (c-src tyrosine kinase [Source:MGI Symbol;Acc:MGI:88537]) HSP 1 Score: 362.844 bits (930), Expect = 9.079e-120 Identity = 193/474 (40.72%), Postives = 267/474 (56.33%), Query Frame = 1
Query: 79 ALYNFEGQKAEDLPFSKGEKLKVLKIISDPNWITCSNNKQHQGLVPVNHVKLSPSLNIED-----PWYHGKVSRSLAEERLMPCENGTFLIRSSDKFPGDYTICVKF-NDVQFYHVIYSNKGYTLDEDSWFASMPELIEHYQKDADGLCCTLTK--CYESPKSRLDYLDENVLNIKFEEIKLGPKIGCGEFSEVLQGEYQDTVVAVKCLKKPINFAEKTLFTFEFSLMAKLNHPHLVTFKG-ISSSNESVYIITEYMENGSLVNYLRSRGRTVIKTNDQIKFAIDSCSGMCYLEEHCLVHRDLAARNILLNAKLVAKVSDFGLARVDDXXXXXXXXXXXXXXXXXXXXXKTPSPKLMLNVVNDLVSLPTSSVDDNTTSVGRIPVKWTAPEALTHNKYTNKSDVWSFGILLWEIFSFGRTPYPRIYANNVKQHLLNGYRMESPEDTPNDIYELMRDCWALEPEKRPTFCEIHKIL 1473
A YNF G +DLPF KG+ L ++ + DPNW N +G++P N+V+ + PW+HGK++R AE L P E G FL+R S +PGDYT+CV V+ Y ++Y ++DE+ +F ++ +L+EHY DADGLC L K E + D + + +E+KL IG GEF +V+ G+Y+ VAVKC+K N A F E S+M +L H +LV G I +YI+TEYM GSLV+YLRSRGR+V+ + +KF++D C M YLE + VHRDLAARN+L++ VAKVSDFGL + SS D G++PVKWTAPEAL K++ KSDVWSFGILLWEI+SFGR PYPRI +V + GY+M++P+ P +YE+M++CW L+ RPTF ++ + L
Sbjct: 16 AKYNFHGTAEQDLPFCKGDVLTIVAVTKDPNWYKAKNKVGREGIIPANYVQKREGVKAGTKLSLMPWFHGKITREQAERLLYPPETGLFLVRESTNYPGDYTLCVSCEGKVEHYRIMYHASKLSIDEEVYFENLMQLVEHYTTDADGLCTRLIKPKVMEGTVAAQDEFYRSGWALNMKELKLLQTIGKGEFGDVMLGDYRGNKVAVKCIK---NDATAQAFLAEASVMTQLRHSNLVQLLGVIVEEKGGLYIVTEYMAKGSLVDYLRSRGRSVLGGDCLLKFSLDVCEAMEYLEGNNFVHRDLAARNVLVSEDNVAKVSDFGLTK------------------------------------------EASSTQDT----GKLPVKWTAPEALREKKFSTKSDVWSFGILLWEIYSFGRVPYPRIPLKDVVPRVEKGYKMDAPDGCPPAVYEVMKNCWHLDAATRPTFLQLREQL 440
BLAST of Tyrosine-protein kinase vs. Ensembl Mouse
Match: Matk (megakaryocyte-associated tyrosine kinase [Source:MGI Symbol;Acc:MGI:99259]) HSP 1 Score: 317.39 bits (812), Expect = 6.595e-102 Identity = 174/472 (36.86%), Postives = 262/472 (55.51%), Query Frame = 1
Query: 103 KAEDLPFSKGEKLKVLKIISDPNWITCSNNKQHQ-GLVPVNHVKLSPSLNIED-----PWYHGKVSRSLAEERLMPCENGTFLIRSSDKFPGDYTICVKFN-DVQFYHVIYSNKGYTLDEDSWFASMPELIEHYQKDADGLCCTLTKCY--ESPKSRLDYLDENVLNIKFEEIKLGPKIGCGEFSEVLQGEYQDTVVAVKCLKKPINFAEKTLFTFEFSLMAKLNHPHLVTFKGISSSNESVYIITEYMENGSLVNYLRSRGRTVIKTNDQIKFAIDSCSGMCYLEEHCLVHRDLAARNILLNAKLVAKVSDFGLARVDDXXXXXXXXXXXXXXXXXXXXXKTPSPKLMLNVVNDLVSLPTSSVDDNTTSVGRIPVKWTAPEALTHNKYTNKSDVWSFGILLWEIFSFGRTPYPRIYANNVKQHLLNGYRMESPEDTPNDIYELMRDCWALEPEKRPTFCEIHKILHKKMKS 1491
K +L F KG+ + +L+ D +W ++ Q GL+ ++ +L+ + PW+HGK+S A ++L P E+G FL+R S + PGDY +CV F DV Y V++ + T+DE F ++ +++EHY KD +C L K + KS + L + + + + LG +IG GEF VLQGEY VAVK +K + F E ++M KL H +LV G+ + +YI+ E++ G+LVN+LR+RGR ++ T+ ++FA+ GM YLE LVHRDLAARNIL++ LVAKVSDFGLA+ + +D + R+PVKWTAPEAL + ++++KSDVWSFG+LLWE+FS+GR PYP++ V + + GYRME P+ P ++ LM CW EP +RP F +I + L ++++S
Sbjct: 22 KPGELAFRKGDMVTILEACEDKSWYRAKHHGSGQEGLLAAAALRQREALSTDPKLSLMPWFHGKISGQEAIQQLQPPEDGLFLVRESARHPGDYVLCVSFGRDVIHYRVLHRDGHLTIDEAVCFCNLMDMVEHYTKDKGAICTKLVKPRRKQGAKSAEEELAKAGWLLDLQHLTLGAQIGEGEFGAVLQGEYLGQKVAVKNIKCDVT---AQAFLDETAVMTKLQHRNLVRLLGVIL-HHGLYIVMEHVSKGNLVNFLRTRGRALVSTSQLLQFALHVAEGMEYLESKKLVHRDLAARNILVSEDLVAKVSDFGLAKAE-----------------------------------------RKGLDSS-----RLPVKWTAPEALKNGRFSSKSDVWSFGVLLWEVFSYGRAPYPKMSLKEVSEAVEKGYRMEPPDGCPGSVHTLMGSCWEAEPARRPPFRKIVEKLGRELRS 443
BLAST of Tyrosine-protein kinase vs. Ensembl Mouse
Match: Matk (megakaryocyte-associated tyrosine kinase [Source:MGI Symbol;Acc:MGI:99259]) HSP 1 Score: 317.39 bits (812), Expect = 6.595e-102 Identity = 174/472 (36.86%), Postives = 262/472 (55.51%), Query Frame = 1
Query: 103 KAEDLPFSKGEKLKVLKIISDPNWITCSNNKQHQ-GLVPVNHVKLSPSLNIED-----PWYHGKVSRSLAEERLMPCENGTFLIRSSDKFPGDYTICVKFN-DVQFYHVIYSNKGYTLDEDSWFASMPELIEHYQKDADGLCCTLTKCY--ESPKSRLDYLDENVLNIKFEEIKLGPKIGCGEFSEVLQGEYQDTVVAVKCLKKPINFAEKTLFTFEFSLMAKLNHPHLVTFKGISSSNESVYIITEYMENGSLVNYLRSRGRTVIKTNDQIKFAIDSCSGMCYLEEHCLVHRDLAARNILLNAKLVAKVSDFGLARVDDXXXXXXXXXXXXXXXXXXXXXKTPSPKLMLNVVNDLVSLPTSSVDDNTTSVGRIPVKWTAPEALTHNKYTNKSDVWSFGILLWEIFSFGRTPYPRIYANNVKQHLLNGYRMESPEDTPNDIYELMRDCWALEPEKRPTFCEIHKILHKKMKS 1491
K +L F KG+ + +L+ D +W ++ Q GL+ ++ +L+ + PW+HGK+S A ++L P E+G FL+R S + PGDY +CV F DV Y V++ + T+DE F ++ +++EHY KD +C L K + KS + L + + + + LG +IG GEF VLQGEY VAVK +K + F E ++M KL H +LV G+ + +YI+ E++ G+LVN+LR+RGR ++ T+ ++FA+ GM YLE LVHRDLAARNIL++ LVAKVSDFGLA+ + +D + R+PVKWTAPEAL + ++++KSDVWSFG+LLWE+FS+GR PYP++ V + + GYRME P+ P ++ LM CW EP +RP F +I + L ++++S
Sbjct: 22 KPGELAFRKGDMVTILEACEDKSWYRAKHHGSGQEGLLAAAALRQREALSTDPKLSLMPWFHGKISGQEAIQQLQPPEDGLFLVRESARHPGDYVLCVSFGRDVIHYRVLHRDGHLTIDEAVCFCNLMDMVEHYTKDKGAICTKLVKPRRKQGAKSAEEELAKAGWLLDLQHLTLGAQIGEGEFGAVLQGEYLGQKVAVKNIKCDVT---AQAFLDETAVMTKLQHRNLVRLLGVIL-HHGLYIVMEHVSKGNLVNFLRTRGRALVSTSQLLQFALHVAEGMEYLESKKLVHRDLAARNILVSEDLVAKVSDFGLAKAE-----------------------------------------RKGLDSS-----RLPVKWTAPEALKNGRFSSKSDVWSFGVLLWEVFSYGRAPYPKMSLKEVSEAVEKGYRMEPPDGCPGSVHTLMGSCWEAEPARRPPFRKIVEKLGRELRS 443
BLAST of Tyrosine-protein kinase vs. UniProt/SwissProt
Match: sp|P41239|CSK_CHICK (Tyrosine-protein kinase CSK OS=Gallus gallus OX=9031 GN=CSK PE=2 SV=1) HSP 1 Score: 368.237 bits (944), Expect = 4.017e-121 Identity = 196/482 (40.66%), Postives = 275/482 (57.05%), Query Frame = 1
Query: 79 ALYNFEGQKAEDLPFSKGEKLKVLKIISDPNWITCSNNKQHQGLVPVNHVKLSPSLNIE-----DPWYHGKVSRSLAEERLMPCENGTFLIRSSDKFPGDYTICVKF-NDVQFYHVIYSNKGYTLDEDSWFASMPELIEHYQKDADGLCCTLTK--CYESPKSRLDYLDENVLNIKFEEIKLGPKIGCGEFSEVLQGEYQDTVVAVKCLKKPINFAEKTLFTFEFSLMAKLNHPHLVTFKGISSSNES-VYIITEYMENGSLVNYLRSRGRTVIKTNDQIKFAIDSCSGMCYLEEHCLVHRDLAARNILLNAKLVAKVSDFGLARVDDXXXXXXXXXXXXXXXXXXXXXKTPSPKLMLNVVNDLVSLPTSSVDDNTTSVGRIPVKWTAPEALTHNKYTNKSDVWSFGILLWEIFSFGRTPYPRIYANNVKQHLLNGYRMESPEDTPNDIYELMRDCWALEPEKRPTFCEIH-KILHKKMKSF 1494
A YNF G +DLPFSKG+ L ++ + DPNW N +G++P N+V+ + PW+HGK++R AE L P E G FL+R S +PGDYT+CV V+ Y +IYS+ ++DE+ +F ++ +L+EHY DADGLC L K E + D + + +++KL IG GEF +V+ G+Y+ VAVKC+K N A F E S+M +L H +LV G+ +S +YI+TEYM GSLV+YLRSRGR+V+ + +KF++D C M YLE + VHRDLAARN+L++ +AKVSDFGL + SS D G++PVKWTAPEAL K++ KSDVWSFGILLWEI+SFGR PYPRI +V + GY+M+ P+ P +YE+M+ CW L+P RP+F ++ +++H K K
Sbjct: 16 AKYNFHGTAEQDLPFSKGDVLTIVAVTKDPNWYKAKNKVGREGIIPANYVQKREGVKAGIKLSLMPWFHGKITREQAERLLYPPETGLFLVRESTNYPGDYTLCVSCEGKVEHYRIIYSSSKLSIDEEVYFENLMQLVEHYTTDADGLCSRLIKPKVMEGTVAAQDEFSRSGWALNMKDLKLLQIIGKGEFGDVMLGDYRGNKVAVKCIK---NDATAQAFLAEASVMTQLRHSNLVQLLGVIVEEKSGLYIVTEYMAKGSLVDYLRSRGRSVLGGDCLLKFSLDVCEAMEYLEANNFVHRDLAARNVLVSEDNIAKVSDFGLTK------------------------------------------EASSTQDT----GKLPVKWTAPEALREKKFSTKSDVWSFGILLWEIYSFGRVPYPRIPLKDVVPRVEKGYKMDPPDGCPAIVYEVMKKCWTLDPGHRPSFHQLREQLVHIKEKEL 448
BLAST of Tyrosine-protein kinase vs. UniProt/SwissProt
Match: sp|P41241|CSK_MOUSE (Tyrosine-protein kinase CSK OS=Mus musculus OX=10090 GN=Csk PE=1 SV=2) HSP 1 Score: 362.844 bits (930), Expect = 6.351e-119 Identity = 193/474 (40.72%), Postives = 267/474 (56.33%), Query Frame = 1
Query: 79 ALYNFEGQKAEDLPFSKGEKLKVLKIISDPNWITCSNNKQHQGLVPVNHVKLSPSLNIED-----PWYHGKVSRSLAEERLMPCENGTFLIRSSDKFPGDYTICVKF-NDVQFYHVIYSNKGYTLDEDSWFASMPELIEHYQKDADGLCCTLTK--CYESPKSRLDYLDENVLNIKFEEIKLGPKIGCGEFSEVLQGEYQDTVVAVKCLKKPINFAEKTLFTFEFSLMAKLNHPHLVTFKG-ISSSNESVYIITEYMENGSLVNYLRSRGRTVIKTNDQIKFAIDSCSGMCYLEEHCLVHRDLAARNILLNAKLVAKVSDFGLARVDDXXXXXXXXXXXXXXXXXXXXXKTPSPKLMLNVVNDLVSLPTSSVDDNTTSVGRIPVKWTAPEALTHNKYTNKSDVWSFGILLWEIFSFGRTPYPRIYANNVKQHLLNGYRMESPEDTPNDIYELMRDCWALEPEKRPTFCEIHKIL 1473
A YNF G +DLPF KG+ L ++ + DPNW N +G++P N+V+ + PW+HGK++R AE L P E G FL+R S +PGDYT+CV V+ Y ++Y ++DE+ +F ++ +L+EHY DADGLC L K E + D + + +E+KL IG GEF +V+ G+Y+ VAVKC+K N A F E S+M +L H +LV G I +YI+TEYM GSLV+YLRSRGR+V+ + +KF++D C M YLE + VHRDLAARN+L++ VAKVSDFGL + SS D G++PVKWTAPEAL K++ KSDVWSFGILLWEI+SFGR PYPRI +V + GY+M++P+ P +YE+M++CW L+ RPTF ++ + L
Sbjct: 16 AKYNFHGTAEQDLPFCKGDVLTIVAVTKDPNWYKAKNKVGREGIIPANYVQKREGVKAGTKLSLMPWFHGKITREQAERLLYPPETGLFLVRESTNYPGDYTLCVSCEGKVEHYRIMYHASKLSIDEEVYFENLMQLVEHYTTDADGLCTRLIKPKVMEGTVAAQDEFYRSGWALNMKELKLLQTIGKGEFGDVMLGDYRGNKVAVKCIK---NDATAQAFLAEASVMTQLRHSNLVQLLGVIVEEKGGLYIVTEYMAKGSLVDYLRSRGRSVLGGDCLLKFSLDVCEAMEYLEGNNFVHRDLAARNVLVSEDNVAKVSDFGLTK------------------------------------------EASSTQDT----GKLPVKWTAPEALREKKFSTKSDVWSFGILLWEIYSFGRVPYPRIPLKDVVPRVEKGYKMDAPDGCPPAVYEVMKNCWHLDAATRPTFLQLREQL 440
BLAST of Tyrosine-protein kinase vs. UniProt/SwissProt
Match: sp|Q0VBZ0|CSK_BOVIN (Tyrosine-protein kinase CSK OS=Bos taurus OX=9913 GN=CSK PE=2 SV=1) HSP 1 Score: 362.073 bits (928), Expect = 1.201e-118 Identity = 192/481 (39.92%), Postives = 272/481 (56.55%), Query Frame = 1
Query: 64 GDFLTALYNFEGQKAEDLPFSKGEKLKVLKIISDPNWITCSNNKQHQGLVPVNHVKLSPSLNIED-----PWYHGKVSRSLAEERLMPCENGTFLIRSSDKFPGDYTICVKFND-VQFYHVIYSNKGYTLDEDSWFASMPELIEHYQKDADGLCCTLTK--CYESPKSRLDYLDENVLNIKFEEIKLGPKIGCGEFSEVLQGEYQDTVVAVKCLKKPINFAEKTLFTFEFSLMAKLNHPHLVTFKGISSSNES-VYIITEYMENGSLVNYLRSRGRTVIKTNDQIKFAIDSCSGMCYLEEHCLVHRDLAARNILLNAKLVAKVSDFGLARVDDXXXXXXXXXXXXXXXXXXXXXKTPSPKLMLNVVNDLVSLPTSSVDDNTTSVGRIPVKWTAPEALTHNKYTNKSDVWSFGILLWEIFSFGRTPYPRIYANNVKQHLLNGYRMESPEDTPNDIYELMRDCWALEPEKRPTFCEIHKILHK 1479
G A YNF G +DLPF KG+ L ++ + DPNW N +G++P N+V+ + PW+HGK++R AE L P E G FL+R S +PGDYT+CV + V+ Y ++Y ++DE+ +F ++ +L+EHY DADGLC L K E + D + + +++KL IG GEF +V+ G+Y+ VAVKC+K N A F E S+M +L H +LV G+ +S +YI+TEYM GSLV+YLRSRGR+V+ + +KF++D C M YLE + VHRDLAARN+L++ VAKVSDFGL + SS D G++PVKWTAPEAL K++ KSDVWSFGILLWEI+SFGR PYPRI +V + GY+M++P+ P +YE+M++CW L+ RP+F ++ + L +
Sbjct: 11 GTECIAKYNFHGTAEQDLPFCKGDVLTIVAVTKDPNWYKAKNKVGREGIIPANYVQKREGVKAGTKLSLMPWFHGKITREQAERLLCPPETGLFLVRESTNYPGDYTLCVSCDGKVEHYRIMYHASKLSIDEEVYFENLMQLVEHYTSDADGLCTRLIKPKVMEGTVAAQDEFFRSGWALNMKDLKLLQTIGKGEFGDVMLGDYRGNKVAVKCIK---NDATAQAFLAEASVMTQLRHSNLVQLLGVIVEEKSGLYIVTEYMAKGSLVDYLRSRGRSVLGGDCLLKFSLDVCEAMEYLEGNNFVHRDLAARNVLVSEDNVAKVSDFGLTK------------------------------------------EASSTQDT----GKLPVKWTAPEALREKKFSTKSDVWSFGILLWEIYSFGRVPYPRIPLKDVVPRVEKGYKMDAPDGCPPAVYEVMKNCWHLDAATRPSFLQLREQLER 442
BLAST of Tyrosine-protein kinase vs. UniProt/SwissProt
Match: sp|P41240|CSK_HUMAN (Tyrosine-protein kinase CSK OS=Homo sapiens OX=9606 GN=CSK PE=1 SV=1) HSP 1 Score: 361.688 bits (927), Expect = 1.624e-118 Identity = 192/474 (40.51%), Postives = 268/474 (56.54%), Query Frame = 1
Query: 79 ALYNFEGQKAEDLPFSKGEKLKVLKIISDPNWITCSNNKQHQGLVPVNHVKLSPSLNIED-----PWYHGKVSRSLAEERLMPCENGTFLIRSSDKFPGDYTICVKFND-VQFYHVIYSNKGYTLDEDSWFASMPELIEHYQKDADGLCCTLTK--CYESPKSRLDYLDENVLNIKFEEIKLGPKIGCGEFSEVLQGEYQDTVVAVKCLKKPINFAEKTLFTFEFSLMAKLNHPHLVTFKG-ISSSNESVYIITEYMENGSLVNYLRSRGRTVIKTNDQIKFAIDSCSGMCYLEEHCLVHRDLAARNILLNAKLVAKVSDFGLARVDDXXXXXXXXXXXXXXXXXXXXXKTPSPKLMLNVVNDLVSLPTSSVDDNTTSVGRIPVKWTAPEALTHNKYTNKSDVWSFGILLWEIFSFGRTPYPRIYANNVKQHLLNGYRMESPEDTPNDIYELMRDCWALEPEKRPTFCEIHKIL 1473
A YNF G +DLPF KG+ L ++ + DPNW N +G++P N+V+ + PW+HGK++R AE L P E G FL+R S +PGDYT+CV + V+ Y ++Y ++DE+ +F ++ +L+EHY DADGLC L K E + D + + +E+KL IG GEF +V+ G+Y+ VAVKC+K N A F E S+M +L H +LV G I +YI+TEYM GSLV+YLRSRGR+V+ + +KF++D C M YLE + VHRDLAARN+L++ VAKVSDFGL + SS D G++PVKWTAPEAL K++ KSDVWSFGILLWEI+SFGR PYPRI +V + GY+M++P+ P +YE+M++CW L+ RP+F ++ + L
Sbjct: 16 AKYNFHGTAEQDLPFCKGDVLTIVAVTKDPNWYKAKNKVGREGIIPANYVQKREGVKAGTKLSLMPWFHGKITREQAERLLYPPETGLFLVRESTNYPGDYTLCVSCDGKVEHYRIMYHASKLSIDEEVYFENLMQLVEHYTSDADGLCTRLIKPKVMEGTVAAQDEFYRSGWALNMKELKLLQTIGKGEFGDVMLGDYRGNKVAVKCIK---NDATAQAFLAEASVMTQLRHSNLVQLLGVIVEEKGGLYIVTEYMAKGSLVDYLRSRGRSVLGGDCLLKFSLDVCEAMEYLEGNNFVHRDLAARNVLVSEDNVAKVSDFGLTK------------------------------------------EASSTQDT----GKLPVKWTAPEALREKKFSTKSDVWSFGILLWEIYSFGRVPYPRIPLKDVVPRVEKGYKMDAPDGCPPAVYEVMKNCWHLDAAMRPSFLQLREQL 440
BLAST of Tyrosine-protein kinase vs. UniProt/SwissProt
Match: sp|P32577|CSK_RAT (Tyrosine-protein kinase CSK OS=Rattus norvegicus OX=10116 GN=Csk PE=1 SV=1) HSP 1 Score: 361.303 bits (926), Expect = 2.369e-118 Identity = 192/474 (40.51%), Postives = 267/474 (56.33%), Query Frame = 1
Query: 79 ALYNFEGQKAEDLPFSKGEKLKVLKIISDPNWITCSNNKQHQGLVPVNHVKLSPSLNIED-----PWYHGKVSRSLAEERLMPCENGTFLIRSSDKFPGDYTICVKF-NDVQFYHVIYSNKGYTLDEDSWFASMPELIEHYQKDADGLCCTLTK--CYESPKSRLDYLDENVLNIKFEEIKLGPKIGCGEFSEVLQGEYQDTVVAVKCLKKPINFAEKTLFTFEFSLMAKLNHPHLVTFKG-ISSSNESVYIITEYMENGSLVNYLRSRGRTVIKTNDQIKFAIDSCSGMCYLEEHCLVHRDLAARNILLNAKLVAKVSDFGLARVDDXXXXXXXXXXXXXXXXXXXXXKTPSPKLMLNVVNDLVSLPTSSVDDNTTSVGRIPVKWTAPEALTHNKYTNKSDVWSFGILLWEIFSFGRTPYPRIYANNVKQHLLNGYRMESPEDTPNDIYELMRDCWALEPEKRPTFCEIHKIL 1473
A YNF G +DLPF KG+ L ++ + DPNW N +G++P N+V+ + PW+HGK++R AE L P E G FL+R S +PGDYT+CV V+ Y ++Y ++DE+ +F ++ +L+EHY DADGLC L K E + D + + +E+KL IG GEF +V+ G+Y+ VAVKC+K N A F E S+M +L H +LV G I +YI+TEYM GSLV+YLRSRGR+V+ + +KF++D C M YLE + VHRDLAARN+L++ VAKVSDFGL + SS D G++PVKWTAPEAL K++ KSDVWSFGILLWEI+SFGR PYPRI +V + GY+M++P+ P +Y++M++CW L+ RPTF ++ + L
Sbjct: 16 AKYNFHGTAEQDLPFCKGDVLTIVAVTKDPNWYKAKNKVGREGIIPANYVQKREGVKAGTKLSLMPWFHGKITREQAERLLYPPETGLFLVRESTNYPGDYTLCVSCEGKVEHYRIMYHASKLSIDEEVYFENLMQLVEHYTTDADGLCTRLIKPKVMEGTVAAQDEFYRSGWALNMKELKLLQTIGKGEFGDVMLGDYRGNKVAVKCIK---NDATAQAFLAEASVMTQLRHSNLVQLLGVIVEEKGGLYIVTEYMAKGSLVDYLRSRGRSVLGGDCLLKFSLDVCEAMEYLEGNNFVHRDLAARNVLVSEDNVAKVSDFGLTK------------------------------------------EASSTQDT----GKLPVKWTAPEALREKKFSTKSDVWSFGILLWEIYSFGRVPYPRIPLKDVVPRVEKGYKMDAPDGCPPAVYDVMKNCWHLDAATRPTFLQLREQL 440
BLAST of Tyrosine-protein kinase vs. TrEMBL
Match: A0A1S3ICC4 (Tyrosine-protein kinase OS=Lingula unguis OX=7574 GN=LOC106176351 PE=3 SV=1) HSP 1 Score: 405.216 bits (1040), Expect = 4.814e-133 Identity = 209/482 (43.36%), Postives = 283/482 (58.71%), Query Frame = 1
Query: 58 KPGDFLTALYNFEGQKAEDLPFSKGEKLKVLKIISDPNWITCSNNKQHQGLVPVNHVKLSPSLNIED-PWYHGKVSRSLAEERLMPCENGTFLIRSSDKFPGDYTICVKF-NDVQFYHVIYSNKGYTLDEDSWFASMPELIEHYQKDADGLCCTLTKCYESPKSRLDY-LDENVL-----NIKFEEIKLGPKIGCGEFSEVLQGEYQDTVVAVKCLKKPINFAEKTLFTFEFSLMAKLNHPHLVTFKGISSSNESVYIITEYMENGSLVNYLRSRGRTVIKTNDQIKFAIDSCSGMCYLEEHCLVHRDLAARNILLNAKLVAKVSDFGLARVDDXXXXXXXXXXXXXXXXXXXXXKTPSPKLMLNVVNDLVSLPTSSVDDNTTSVGRIPVKWTAPEALTHNKYTNKSDVWSFGILLWEIFSFGRTPYPRIYANNVKQHLLNGYRMESPEDTPNDIYELMRDCWALEPEKRPTFCEIHKILHK 1479
+PG + A Y F+G EDLPF KG+ L ++K DP W + +G++P N+V+ + + PW+HGK+ R AEE L P E G FL+R S +PGDYT+CV N V+ YH+IY T+DE+ +F ++ EL+EHY+ DADGLC L K K ++Y +D+ +IK +++ G IG GEF +V +GE++ VA+K LK N A++ F E SLM L H +LV G+ E +YI+TE+M G+LV+YLR+RGR+VI D + FA D+C GM YLE LVHRDLAARN+L++ VAKVSDFGLAR D+ + G+ P+KWTAPEAL NK+TNKSD+WSFGIL+WEI+SFGR PYPRI +V H+ GYRME PE PN++YE+MR W L+P +RPTF ++ L K
Sbjct: 13 QPGQEVLARYTFQGNSREDLPFQKGDVLTIIKATRDPMWYHARRSDNKEGMIPANYVQKRSEVKLHAMPWFHGKIKREQAEELLQPREEGLFLVRESTNYPGDYTLCVAHKNSVEHYHIIYKLNKLTIDEEEYFDNLNELVEHYKNDADGLCTKLRKSVPKTKGGMEYTVDKRQFMDAGWSIKEKDLIKGETIGRGEFGDVRKGEFKGVPVAIKYLKDTDNAAQQ--FLAEASLMTSLKHRNLVQLIGVVLGQE-IYIVTEFMAKGNLVDYLRTRGRSVITKRDLLNFASDTCEGMAYLETKSLVHRDLAARNVLISEDGVAKVSDFGLAR----------------------------------------------RADSNQAGGKFPIKWTAPEALRENKFTNKSDMWSFGILIWEIYSFGRVPYPRIPLADVVMHVERGYRMEKPEGCPNEVYEVMRKAWDLDPARRPTFADVKVELEK 445
BLAST of Tyrosine-protein kinase vs. TrEMBL
Match: L7M1U7 (Tyrosine-protein kinase OS=Rhipicephalus pulchellus OX=72859 PE=2 SV=1) HSP 1 Score: 394.43 bits (1012), Expect = 6.527e-129 Identity = 208/481 (43.24%), Postives = 282/481 (58.63%), Query Frame = 1
Query: 55 LKPGDFLTALYNFEGQKAEDLPFSKGEKLKVLKIISDPNWITCSNNKQHQGLVPVNHVKLSPSLNIED-PWYHGKVSRSLAEERLMPCENGTFLIRSSDKFPGDYTICVKF-NDVQFYHVIYSNKGYTLDEDSWFASMPELIEHYQKDADGLCCTLTKCYESPKSRLDYLDENVLN-----IKFEEIKLGPKIGCGEFSEVLQGEYQDTVVAVKCLKKPINFAEKTLFTFEFSLMAKLNHPHLVTFKGISSSNESVYIITEYMENGSLVNYLRSRGRTVIKTNDQIKFAIDSCSGMCYLEEHCLVHRDLAARNILLNAKLVAKVSDFGLARVDDXXXXXXXXXXXXXXXXXXXXXKTPSPKLMLNVVNDLVSLPTSSVDDNTTSVGRIPVKWTAPEALTHNKYTNKSDVWSFGILLWEIFSFGRTPYPRIYANNVKQHLLNGYRMESPEDTPNDIYELMRDCWALEPEKRPTFCEIHKILH 1476
L PG + A YNF G+ AEDL F+KG+ + ++ D NW + +GL+P+N++ + + PW+HGK+SR AE L P E+G FL+R S +PGDYT+CV F + V+ Y VIY T+DE+ +F +P+LIEHY++DADGLC L++ L +D IK +++++ IG GEF +VL Y+ VAVK +K+ + K + E SLM L HP+LV G+ S+ I+TEYM GSLV+YLRSRGR + DQI FA D+C+GM YLE +VHRDLAARN+L++ VAKVSDFGLA+ + DN G+ P+KWTAPEAL NK++NKSD+WSFGILLWEI+SFGR PYPRI +V +H+ GYRMESPE P+D+YELMR W EP++RPTF ++ + L
Sbjct: 2 LPPGTEVVARYNFNGKSAEDLSFTKGDIMTIVSETPDCNWFRARHTDGREGLIPLNYILRRAEVKLNSMPWFHGKISRERAEMLLQPREDGLFLVRESTNYPGDYTLCVCFRSKVEHYRVIYRMGKLTIDEEEYFEGLPQLIEHYEQDADGLCTRLSRSVPKQGGEL-AIDHRAFEMAGWAIKKQDLQVIENIGKGEFGDVLLATYKGQKVAVKKIKE----SGKNMLIAEASLMTSLRHPNLVQLLGLVIEENSLQIVTEYMAKGSLVDYLRSRGRLHVTRIDQINFATDTCAGMAYLESKHVVHRDLAARNVLISDDGVAKVSDFGLAKDE---------------------------------------------SDNLEG-GKFPIKWTAPEALKCNKFSNKSDMWSFGILLWEIYSFGRVPYPRIPLADVVRHVSKGYRMESPEGCPSDVYELMRAAWQEEPQERPTFAQVLRKLQ 431
BLAST of Tyrosine-protein kinase vs. TrEMBL
Match: A0A224YUT6 (Tyrosine-protein kinase OS=Rhipicephalus zambeziensis OX=60191 PE=3 SV=1) HSP 1 Score: 393.66 bits (1010), Expect = 1.086e-128 Identity = 207/481 (43.04%), Postives = 282/481 (58.63%), Query Frame = 1
Query: 55 LKPGDFLTALYNFEGQKAEDLPFSKGEKLKVLKIISDPNWITCSNNKQHQGLVPVNHVKLSPSLNIED-PWYHGKVSRSLAEERLMPCENGTFLIRSSDKFPGDYTICVKF-NDVQFYHVIYSNKGYTLDEDSWFASMPELIEHYQKDADGLCCTLTKCYESPKSRLDYLDENVLN-----IKFEEIKLGPKIGCGEFSEVLQGEYQDTVVAVKCLKKPINFAEKTLFTFEFSLMAKLNHPHLVTFKGISSSNESVYIITEYMENGSLVNYLRSRGRTVIKTNDQIKFAIDSCSGMCYLEEHCLVHRDLAARNILLNAKLVAKVSDFGLARVDDXXXXXXXXXXXXXXXXXXXXXKTPSPKLMLNVVNDLVSLPTSSVDDNTTSVGRIPVKWTAPEALTHNKYTNKSDVWSFGILLWEIFSFGRTPYPRIYANNVKQHLLNGYRMESPEDTPNDIYELMRDCWALEPEKRPTFCEIHKILH 1476
L PG + A YNF G+ EDL F+KG+ + ++ D NW + +GL+P+N++ + + PW+HGK+SR AE L P E+G FL+R S +PGDYT+CV F + V+ Y VIY T+DE+ +F +P+LIEHY++DADGLC L++ L +D IK +++++ IG GEF +VL Y+ VAVK +K+ + K + E SLM L HP+LV G+ + S+ I+TEYM GSLV+YLRSRGR + DQI FA D+C+GM YLE +VHRDLAARN+L++ VAKVSDFGLA+ + DN G+ P+KWTAPEAL NK++NKSD+WSFGILLWEI+SFGR PYPRI +V +H+ GYRMESPE P+D+YELMR W EP++RPTF ++ + L
Sbjct: 2 LPPGTEVVARYNFNGKSTEDLSFTKGDIMTIVSETPDCNWFRARHTDGREGLIPLNYILRRAEVKLNSMPWFHGKISRERAEMLLQPREDGLFLVRESTNYPGDYTLCVCFRSKVEHYRVIYRMGKLTIDEEEYFEGLPQLIEHYEQDADGLCTRLSRSVPKQGGEL-AIDHRAFEMAGWAIKKQDLQVVENIGKGEFGDVLLATYKGQKVAVKKIKE----SGKNMLIAEASLMTSLRHPNLVQLLGLVIEDNSLQIVTEYMAKGSLVDYLRSRGRLHVTRVDQINFATDTCAGMAYLESKHVVHRDLAARNVLISDDGVAKVSDFGLAKDE---------------------------------------------SDNLEG-GKFPIKWTAPEALKCNKFSNKSDMWSFGILLWEIYSFGRVPYPRIPLADVVRHVSKGYRMESPEGCPSDVYELMRAAWQEEPQERPTFAQVLRKLQ 431
BLAST of Tyrosine-protein kinase vs. TrEMBL
Match: A0A131YWK3 (Tyrosine-protein kinase OS=Rhipicephalus appendiculatus OX=34631 PE=3 SV=1) HSP 1 Score: 393.66 bits (1010), Expect = 1.086e-128 Identity = 207/481 (43.04%), Postives = 282/481 (58.63%), Query Frame = 1
Query: 55 LKPGDFLTALYNFEGQKAEDLPFSKGEKLKVLKIISDPNWITCSNNKQHQGLVPVNHVKLSPSLNIED-PWYHGKVSRSLAEERLMPCENGTFLIRSSDKFPGDYTICVKF-NDVQFYHVIYSNKGYTLDEDSWFASMPELIEHYQKDADGLCCTLTKCYESPKSRLDYLDENVLN-----IKFEEIKLGPKIGCGEFSEVLQGEYQDTVVAVKCLKKPINFAEKTLFTFEFSLMAKLNHPHLVTFKGISSSNESVYIITEYMENGSLVNYLRSRGRTVIKTNDQIKFAIDSCSGMCYLEEHCLVHRDLAARNILLNAKLVAKVSDFGLARVDDXXXXXXXXXXXXXXXXXXXXXKTPSPKLMLNVVNDLVSLPTSSVDDNTTSVGRIPVKWTAPEALTHNKYTNKSDVWSFGILLWEIFSFGRTPYPRIYANNVKQHLLNGYRMESPEDTPNDIYELMRDCWALEPEKRPTFCEIHKILH 1476
L PG + A YNF G+ EDL F+KG+ + ++ D NW + +GL+P+N++ + + PW+HGK+SR AE L P E+G FL+R S +PGDYT+CV F + V+ Y VIY T+DE+ +F +P+LIEHY++DADGLC L++ L +D IK +++++ IG GEF +VL Y+ VAVK +K+ + K + E SLM L HP+LV G+ + S+ I+TEYM GSLV+YLRSRGR + DQI FA D+C+GM YLE +VHRDLAARN+L++ VAKVSDFGLA+ + DN G+ P+KWTAPEAL NK++NKSD+WSFGILLWEI+SFGR PYPRI +V +H+ GYRMESPE P+D+YELMR W EP++RPTF ++ + L
Sbjct: 2 LPPGTEVVARYNFNGKSTEDLSFTKGDIMTIVSETPDCNWFRARHTDGREGLIPLNYILRRAEVKLNSMPWFHGKISRERAEMLLQPREDGLFLVRESTNYPGDYTLCVCFRSKVEHYRVIYRMGKLTIDEEEYFEGLPQLIEHYEQDADGLCTRLSRSVPKQGGEL-AIDHRAFEMAGWAIKKQDLQVVENIGKGEFGDVLLATYKGQKVAVKKIKE----SGKNMLIAEASLMTSLRHPNLVQLLGLVIEDNSLQIVTEYMAKGSLVDYLRSRGRLHVTRVDQINFATDTCAGMAYLESKHVVHRDLAARNVLISDDGVAKVSDFGLAKDE---------------------------------------------SDNLEG-GKFPIKWTAPEALKCNKFSNKSDMWSFGILLWEIYSFGRVPYPRIPLADVVRHVSKGYRMESPEGCPSDVYELMRAAWQEEPQERPTFAQVLRKLQ 431
BLAST of Tyrosine-protein kinase vs. TrEMBL
Match: A0A1Z5KWJ4 (Tyrosine-protein kinase (Fragment) OS=Ornithodoros moubata OX=6938 PE=3 SV=1) HSP 1 Score: 393.275 bits (1009), Expect = 1.484e-128 Identity = 206/476 (43.28%), Postives = 276/476 (57.98%), Query Frame = 1
Query: 55 LKPGDFLTALYNFEGQKAEDLPFSKGEKLKVLKIISDPNWITCSNNKQHQGLVPVNHVKLSPSLNIED-PWYHGKVSRSLAEERLMPCENGTFLIRSSDKFPGDYTICVKF-NDVQFYHVIYSNKGYTLDEDSWFASMPELIEHYQKDADGLCCTLTKCYESPKSRLDYLDENVLN-----IKFEEIKLGPKIGCGEFSEVLQGEYQDTVVAVKCLKKPINFAEKTLFTFEFSLMAKLNHPHLVTFKGISSSNESVYIITEYMENGSLVNYLRSRGRTVIKTNDQIKFAIDSCSGMCYLEEHCLVHRDLAARNILLNAKLVAKVSDFGLARVDDXXXXXXXXXXXXXXXXXXXXXKTPSPKLMLNVVNDLVSLPTSSVDDNTTSVGRIPVKWTAPEALTHNKYTNKSDVWSFGILLWEIFSFGRTPYPRIYANNVKQHLLNGYRMESPEDTPNDIYELMRDCWALEPEKRPTFCEI 1461
L G + A YNF + EDL F+KG+ + ++ DPNW +N +GL+P+N++ + + PW+HGK++R AE L P E+G FL+R S +PGDYT+CV + V+ Y VIY T+DE+ +F +P+LIEHYQ DADGLC L++ L +D IK +++ + IG GEF +VL Y+ VAVK +K+ + K + E SLM L HP+LV G+ + S+ I+TEYM GSLV+YLRSRGR + DQI FA D+C+GM YLE +VHRDLAARN+L++ +AKVSDFGLAR + DN G+ P+KWTAPEAL N+++NKSD+WSFGILLWEI+SFGR PYPRI +V +H+ GYRMESPE P DIYELMR W +P+KRPTF E+
Sbjct: 2 LPSGTEVVARYNFIAKSREDLSFTKGDLMTIVSGTPDPNWFRAKHNDGREGLIPLNYILRRAEVKLNSMPWFHGKITRDKAEALLSPREDGLFLVRESTNYPGDYTLCVCYRGKVEHYRVIYRENKLTIDEEEYFEGLPQLIEHYQNDADGLCTRLSRSVPKQDGEL-VIDHRAFEMAGWAIKKQDLHVIENIGKGEFGDVLLANYKGQKVAVKKIKE----SGKNMLIAEASLMTSLRHPNLVQLLGLVIEDNSLQIVTEYMSKGSLVDYLRSRGRLHVTKQDQINFATDTCAGMAYLESKHVVHRDLAARNVLISEDCIAKVSDFGLARDE---------------------------------------------SDNLEG-GKFPIKWTAPEALKCNRFSNKSDMWSFGILLWEIYSFGRVPYPRIPLADVVRHVSKGYRMESPEGCPTDIYELMRSAWQEDPDKRPTFAEV 426
BLAST of Tyrosine-protein kinase vs. Ensembl Cavefish
Match: csk (tyrosine-protein kinase CSK [Source:NCBI gene;Acc:103033740]) HSP 1 Score: 357.836 bits (917), Expect = 5.515e-118 Identity = 192/481 (39.92%), Postives = 266/481 (55.30%), Query Frame = 1
Query: 61 PGDFLTALYNFEGQKAEDLPFSKGEKLKVLKIISDPNWITCSNNKQHQGLVPVNHVKLSPSLNIED-----PWYHGKVSRSLAEERLMPCENGTFLIRSSDKFPGDYTICVKFND-VQFYHVIYSNKGYTLDEDSWFASMPELIEHYQKDADGLCCTLTK--CYESPKSRLDYLDENVLNIKFEEIKLGPKIGCGEFSEVLQGEYQDTVVAVKCLKKPINFAEKTLFTFEFSLMAKLNHPHLVTFKG-ISSSNESVYIITEYMENGSLVNYLRSRGRTVIKTNDQIKFAIDSCSGMCYLEEHCLVHRDLAARNILLNAKLVAKVSDFGLARVDDXXXXXXXXXXXXXXXXXXXXXKTPSPKLMLNVVNDLVSLPTSSVDDNTTSVGRIPVKWTAPEALTHNKYTNKSDVWSFGILLWEIFSFGRTPYPRIYANNVKQHLLNGYRMESPEDTPNDIYELMRDCWALEPEKRPTFCEIHKILH 1476
PG A YNF G +DLP KG+ L ++ + DPNW N +G +P N+V+ + PW+HGK++R AE L P E G FL+R S FPGDYT+CV + V+ Y ++Y N ++DE+ +F ++ +L+EHY KDADGLC L K E + D + + +E+KL IG GEF +V+ G+Y+ T VAVKC+K + A F E S+M ++ H +LV G I S+YI+TEYM GSLV+YLRSRGRT+I + +KF+++ C M YLE + VHRDLAARN+L++ +AKVSDFGL + SS D ++PVKWTAPEAL ++ KSDVWS+GILLWEI+SFGR PYPRI +V + GY+M++P+ P +Y +M+ CW L+ RPTF + L
Sbjct: 10 PGTECVARYNFPGTTDQDLPLCKGDVLTIIGVTKDPNWYKAKNTVGREGTIPANYVQKREGVKSGGKLSLMPWFHGKITREQAERLLYPPETGLFLVRESTNFPGDYTLCVSCDGKVEHYRIVYQNCKLSIDEEEFFENLMQLVEHYTKDADGLCTRLIKPKLMEGTVAAQDEFSRSGWALNRKELKLLQAIGKGEFGDVMVGDYRGTKVAVKCIK---HDATAQAFVAEASVMTQMRHNNLVQLLGVIVEEKGSLYIVTEYMAKGSLVDYLRSRGRTIIGGDCLLKFSMNVCEAMEYLEANNFVHRDLAARNVLVSDDNIAKVSDFGLTK------------------------------------------EASSTQDT----AKLPVKWTAPEALREKTFSTKSDVWSYGILLWEIYSFGRVPYPRIPLKDVVPRVEKGYKMDAPDGCPPAVYNIMKQCWTLDVNMRPTFNALRDSLQ 441
BLAST of Tyrosine-protein kinase vs. Ensembl Cavefish
Match: CSK (C-terminal Src kinase [Source:NCBI gene;Acc:103023502]) HSP 1 Score: 354.755 bits (909), Expect = 7.664e-117 Identity = 190/484 (39.26%), Postives = 271/484 (55.99%), Query Frame = 1
Query: 64 GDFLTALYNFEGQKAEDLPFSKGEKLKVLKIISDPNWITCSNNKQHQGLVPVNHVKLSPSLNIED-----PWYHGKVSRSLAEERLMPCENGTFLIRSSDKFPGDYTICVKF-NDVQFYHVIYSNKGYTLDEDSWFASMPELIEHYQKDADGLCCTLTK--CYESPKSRLDYLDENVLNIKFEEIKLGPKIGCGEFSEVLQGEYQDTVVAVKCLKKPINFAEKTLFTFEFSLMAKLNHPHLVTFKG-ISSSNESVYIITEYMENGSLVNYLRSRGRTVIKTNDQIKFAIDSCSGMCYLEEHCLVHRDLAARNILLNAKLVAKVSDFGLARVDDXXXXXXXXXXXXXXXXXXXXXKTPSPKLMLNVVNDLVSLPTSSVDDNTTSVGRIPVKWTAPEALTHNKYTNKSDVWSFGILLWEIFSFGRTPYPRIYANNVKQHLLNGYRMESPEDTPNDIYELMRDCWALEPEKRPTFCEIHKILHKKMK 1488
G A YNF+G +DLPF KG+ L ++ + DPNW N +G +P N+V+ + PW+HGK++R AE L P E G +L+R S +PGDYT+CV V+ Y +IY N ++DE+ +F ++ +L+EHY KDADGLC L K E + D + + +++KL IG GEF +V+ G+Y+ T VAVKC+K A F E S+M +L H +LV G I S++I+TEYM GSLV+YLRSRGRTV+ + +KF++D C M YLE + VHRDLAARN+L++ +AKVSDFGL + SS D ++PVKWT+PEAL +++ KSDVWS+G+LLWEI+SFGR PYPRI V + GY+M++P+ P +Y+LM+ CW L+ RP+F ++L +K++
Sbjct: 11 GTECVAKYNFQGTTEQDLPFCKGDVLTIIGVTKDPNWYKAKNTVGREGTIPANYVQKREGVKSGGKLSLMPWFHGKITRDQAERLLYPPETGLYLVRESTNYPGDYTLCVSCEGKVEHYRIIYHNGKLSIDEEEFFENLMQLVEHYTKDADGLCTRLIKPKLMEGTVAAQDEFSRSGWALSRKDLKLIQTIGKGEFGDVMVGDYRGTKVAVKCIKHD---ATAQAFIAEASVMTQLRHNNLVQLLGVIVEERGSLFIVTEYMAKGSLVDYLRSRGRTVLGGDCLLKFSLDVCEAMEYLEVNNFVHRDLAARNVLVSEDNIAKVSDFGLTK------------------------------------------EASSTQDT----AKLPVKWTSPEALREKRFSTKSDVWSYGVLLWEIYSFGRVPYPRIPLKEVVPRVEKGYKMDAPDGCPAVVYDLMKQCWTLDSVMRPSF----RMLREKLQ 441
BLAST of Tyrosine-protein kinase vs. Ensembl Cavefish
Match: CSK (C-terminal Src kinase [Source:NCBI gene;Acc:103023502]) HSP 1 Score: 354.755 bits (909), Expect = 9.386e-117 Identity = 190/484 (39.26%), Postives = 272/484 (56.20%), Query Frame = 1
Query: 64 GDFLTALYNFEGQKAEDLPFSKGEKLKVLKIISDPNWITCSNNKQHQGLVPVNHVKLSPSLNIED-----PWYHGKVSRSLAEERLMPCENGTFLIRSSDKFPGDYTICVKF-NDVQFYHVIYSNKGYTLDEDSWFASMPELIEHYQKDADGLCCTLTK--CYESPKSRLDYLDENVLNIKFEEIKLGPKIGCGEFSEVLQGEYQDTVVAVKCLKKPINFAEKTLFTFEFSLMAKLNHPHLVTFKG-ISSSNESVYIITEYMENGSLVNYLRSRGRTVIKTNDQIKFAIDSCSGMCYLEEHCLVHRDLAARNILLNAKLVAKVSDFGLARVDDXXXXXXXXXXXXXXXXXXXXXKTPSPKLMLNVVNDLVSLPTSSVDDNTTSVGRIPVKWTAPEALTHNKYTNKSDVWSFGILLWEIFSFGRTPYPRIYANNVKQHLLNGYRMESPEDTPNDIYELMRDCWALEPEKRPTFCEIHKILHKKMK 1488
G A YNF+G +DLPF KG+ L ++ + DPNW N +G +P N+V+ + PW+HGK++R AE L P E G +L+R S +PGDYT+CV V+ Y +IY N ++DE+ +F ++ +L+EHY KDADGLC L K E + D + + +++KL IG GEF +V+ G+Y+ T VAVKC+K + A F E S+M +L H +LV G I S++I+TEYM GSLV+YLRSRGRTV+ + +KF++D C M YLE + VHRDLAARN+L++ +AKVSDFGL + SS D ++PVKWT+PEAL +++ KSDVWS+G+LLWEI+SFGR PYPRI V + GY+M++P+ P +Y+LM+ CW L+ RP+F ++L +K++
Sbjct: 14 GTECVAKYNFQGTTEQDLPFCKGDVLTIIGVTKDPNWYKAKNTVGREGTIPANYVQKREGVKSGGKLSLMPWFHGKITRDQAERLLYPPETGLYLVRESTNYPGDYTLCVSCEGKVEHYRIIYHNGKLSIDEEEFFENLMQLVEHYTKDADGLCTRLIKPKLMEGTVAAQDEFSRSGWALSRKDLKLIQTIGKGEFGDVMVGDYRGTKVAVKCIK---HDATAQAFIAEASVMTQLRHNNLVQLLGVIVEERGSLFIVTEYMAKGSLVDYLRSRGRTVLGGDCLLKFSLDVCEAMEYLEVNNFVHRDLAARNVLVSEDNIAKVSDFGLTK------------------------------------------EASSTQDT----AKLPVKWTSPEALREKRFSTKSDVWSYGVLLWEIYSFGRVPYPRIPLKEVVPRVEKGYKMDAPDGCPAVVYDLMKQCWTLDSVMRPSF----RMLREKLQ 444
BLAST of Tyrosine-protein kinase vs. Ensembl Cavefish
Match: matk (megakaryocyte-associated tyrosine kinase [Source:NCBI gene;Acc:103034670]) HSP 1 Score: 317.775 bits (813), Expect = 1.769e-102 Identity = 183/486 (37.65%), Postives = 261/486 (53.70%), Query Frame = 1
Query: 58 KPGDFLTALYNFEGQKAEDLPFSKGEKLKVLKIISDPNWI--TCSNNKQHQGLVPVNHVKLSPSLNIED-----PWYHGKVSRSLAEERLMPCENGTFLIRSSDKFPGDYTICVKF-NDVQFYHVIYSNKGYTLDEDSWFASMPELIEHYQKDADGLCCTLTKCYESPKSRLDYLD--ENVLNIKFEEIKLGPKIGCGEFSEVLQGEYQDTVVAVKCLKKPINFAEKTLFTFEFSLMAKLNHPHLVTFKGISSSNESVYIITEYMENGSLVNYLRSRGRTVIKTNDQIKFAIDSCSGMCYLEEHCLVHRDLAARNILLNAKLVAKVSDFGLARVDDXXXXXXXXXXXXXXXXXXXXXKTPSPKLMLNVVNDLVSLPTSSVDDNTTSVGRIPVKWTAPEALTHNKYTNKSDVWSFGILLWEIFSFGRTPYPRIYANNVKQHLLNGYRMESPEDTPNDIYELMRDCWALEPEKRPTFCEIHKILHKKM 1485
+PG A + K ++ + KG+ L +L ++ I N +G++ + V+ L ++ PW+HGK+S A +L P E+G FL+R S + PGDY +CV F +V Y VIY + T+D F ++ +++E Y K+ L TL K + +R L + + + LG IG GEF V +GEY VAVK +K + F E S+M KL H +LV G+ N +YI+TE+M G+LVNYLRSRGR+VI T + +A++ C GM YLE LVHRDLAARNILL+ VAKVSDFGLA+VD S DNT ++PVKWTAPE L + K + +SDVWS+G+LLWEIFS+G PYP++ VK+ + GYRME+PE P ++Y +MRDCW EP+ RP+F ++ ++L ++
Sbjct: 7 QPGTQCVAKCDHTKPKGNEIAYLKGDILTILDVLETGKSIFRARHNRTGEEGVLSASKVREREVLRVDPNLSLMPWFHGKISGPEAVSKLRPMEDGLFLVRESIRHPGDYVLCVSFKQEVIHYRVIYQDSKLTIDSTQHFYNLIDMVEFYSKNKGALVTTLQKPKQKEGARSAALQLYKTGWLLDLAGLTLGESIGEGEFGAVYEGEYMGRKVAVKNIKSDVT---AQAFLGETSVMTKLQHKNLVQLLGVILHN-GLYIVTEFMAKGNLVNYLRSRGRSVISTVQLLHYALEVCEGMEYLECKKLVHRDLAARNILLSEDNVAKVSDFGLAKVD------------------------------------------SQAFDNT----KLPVKWTAPEGLKNKKISTRSDVWSYGVLLWEIFSYGMQPYPKMSLQEVKEQVEQGYRMEAPEACPPEVYTIMRDCWEKEPKMRPSFHKLRELLQAEV 442
BLAST of Tyrosine-protein kinase vs. Ensembl Cavefish
Match: matk (megakaryocyte-associated tyrosine kinase [Source:NCBI gene;Acc:103034670]) HSP 1 Score: 312.383 bits (799), Expect = 1.140e-100 Identity = 172/423 (40.66%), Postives = 240/423 (56.74%), Query Frame = 1
Query: 226 VKLSPSLNIEDPWYHGKVSRSLAEERLMPCENGTFLIRSSDKFPGDYTICVKF-NDVQFYHVIYSNKGYTLDEDSWFASMPELIEHYQKDADGLCCTLTKCYESPKSRLDYLD--ENVLNIKFEEIKLGPKIGCGEFSEVLQGEYQDTVVAVKCLKKPINFAEKTLFTFEFSLMAKLNHPHLVTFKGISSSNESVYIITEYMENGSLVNYLRSRGRTVIKTNDQIKFAIDSCSGMCYLEEHCLVHRDLAARNILLNAKLVAKVSDFGLARVDDXXXXXXXXXXXXXXXXXXXXXKTPSPKLMLNVVNDLVSLPTSSVDDNTTSVGRIPVKWTAPEALTHNKYTNKSDVWSFGILLWEIFSFGRTPYPRIYANNVKQHLLNGYRMESPEDTPNDIYELMRDCWALEPEKRPTFCEIHKILHKKM 1485
+++ P+L++ PW+HGK+S A +L P E+G FL+R S + PGDY +CV F +V Y VIY + T+D F ++ +++E Y K+ L TL K + +R L + + + LG IG GEF V +GEY VAVK +K + F E S+M KL H +LV G+ N +YI+TE+M G+LVNYLRSRGR+VI T + +A++ C GM YLE LVHRDLAARNILL+ VAKVSDFGLA+VD S DNT ++PVKWTAPE L + K + +SDVWS+G+LLWEIFS+G PYP++ VK+ + GYRME+PE P ++Y +MRDCW EP+ RP+F ++ ++L ++
Sbjct: 44 LRVDPNLSLM-PWFHGKISGPEAVSKLRPMEDGLFLVRESIRHPGDYVLCVSFKQEVIHYRVIYQDSKLTIDSTQHFYNLIDMVEFYSKNKGALVTTLQKPKQKEGARSAALQLYKTGWLLDLAGLTLGESIGEGEFGAVYEGEYMGRKVAVKNIKSDVT---AQAFLGETSVMTKLQHKNLVQLLGVILHN-GLYIVTEFMAKGNLVNYLRSRGRSVISTVQLLHYALEVCEGMEYLECKKLVHRDLAARNILLSEDNVAKVSDFGLAKVD------------------------------------------SQAFDNT----KLPVKWTAPEGLKNKKISTRSDVWSYGVLLWEIFSYGMQPYPKMSLQEVKEQVEQGYRMEAPEACPPEVYTIMRDCWEKEPKMRPSFHKLRELLQAEV 415
BLAST of Tyrosine-protein kinase vs. Ensembl Sea Lamprey
Match: hck (HCK proto-oncogene, Src family tyrosine kinase [Source:ZFIN;Acc:ZDB-GENE-090313-72]) HSP 1 Score: 270.781 bits (691), Expect = 4.404e-85 Identity = 164/483 (33.95%), Postives = 252/483 (52.17%), Query Frame = 1
Query: 67 DFLTALYNFEGQKAEDLPFSKGEKLKVLKIISDPNWITCSNNKQHQGLVPVNHVKLSPSLNIEDPWYHGKVSRSLAEERLMPCEN--GTFLIRSSDKFPGDYTICVKFNDVQFYHVIYSNKGYTLDEDSWFAS----MPEL---IEHYQKDADGLCCTLTKCYESPKSRLDYLDENVLNIKFEEIKLGPKIGCGEFSEVLQGEYQD-TVVAVKCLKKPINFAEKTLFTFEFSLMAKLNHPHLVTFKGISSSNESVYIITEYMENGSLVNYLRSRGRTVIKTNDQIKFAIDSCSGMCYLEEHCLVHRDLAARNILLNAKLVAKVSDFGLARVDDXXXXXXXXXXXXXXXXXXXXXKTPSPKLMLNVVNDLVSLPTSSVDDNTTSV---GRIPVKWTAPEALTHNKYTNKSDVWSFGILLWEIFSFGRTPYPRIYANNVKQHLLNGYRMESPEDTPNDIYELMRDCWALEPEKRPTFCEIHKILH 1476
+ + ALY+FE +D+ F KG+K+++++ + W+ + H+G +P N+V + SL E+ W+ VSR E L+ N G +L+R S+ G Y++ V+ D+ V+ K TLD +F S P+L I+HY +DGLC L + S K + +++ I + +KL ++G G+F EV G Y + T VA+K +K P + + + F E +LM L HP LV + + E +YI+TE+MENGSL++YL+S + + I A GM ++E +HRDL A NIL+N +L +K++DFGLAR+ ++DN + + P+KWTAPEA+ + ++ KSDVWSFGILL EI +FGR PYP + ++V + L GYRM PE P +Y +M DCW PE+RPTF + +L
Sbjct: 1 ELVVALYDFEQLNPDDMGFKKGDKMRIIQERGE-WWMAELMDGSHKGYIPSNYVAKANSLETEE-WFFSGVSRKEGERLLLAPGNSIGAYLLRDSESNKGSYSLSVRDYDITNGDVVRHYKIRTLDNGGYFISARLTFPDLFALIQHYTAHSDGLCQKLLRPCVSKKPQ-QLWEKDAWEIPRDSLKLSKRLGAGQFGEVWMGIYNNRTKVAIKTMK-PGSMSPEA-FLDEANLMKTLQHPRLVRLYAVVT-QEPIYIVTEFMENGSLLDYLKSTEGSTLPMPKMIDMAAQIAEGMAFIERKNYIHRDLRAANILVNEQLASKIADFGLARI---------------------------------------------IEDNEYTAREGAKFPIKWTAPEAINYGSFSIKSDVWSFGILLTEIITFGRIPYPGMSNSDVIRQLERGYRMPCPEQAPKQLYGVMMDCWKERPEERPTFEYLQGVLE 432
BLAST of Tyrosine-protein kinase vs. Ensembl Sea Lamprey
Match: frk (fyn-related Src family tyrosine kinase [Source:ZFIN;Acc:ZDB-GENE-110411-7]) HSP 1 Score: 262.307 bits (669), Expect = 1.278e-81 Identity = 165/477 (34.59%), Postives = 251/477 (52.62%), Query Frame = 1
Query: 76 TALYNFEGQKAEDLPFSKGEKLKVLKIISDPNW------ITCSNNKQH-QGLVPVNHVKLSPSLNIEDPWYHGKVSRSLAEERLMPCEN--GTFLIRSSDKFPGDYTICVK-FNDVQFYHV--IYSNKGYTLDEDSWFASMPELIEHYQKDADGLCCTLTK---CYESPKS-RLDYLDENVLNIKFEEIKLGPKIGCGEFSEVLQGEYQD-TVVAVKCLKKPINFAEKTLFTFEFSLMAKLNHPHLVTFKGISSSNESVYIITEYMENGSLVNYLRSRGRTVIKTNDQIKFAIDSCSGMCYLEEHCLVHRDLAARNILLNAKLVAKVSDFGLARVDDXXXXXXXXXXXXXXXXXXXXXKTPSPKLMLNVVNDLVSLPTSSVDDNTTSVG-RIPVKWTAPEALTHNKYTNKSDVWSFGILLWEIFSFGRTPYPRIYANNVKQHLLNGYRMESPEDTPNDIYELMRDCWALEPEKRPTF 1452
ALY+++G+ EDL F +GE L+V + W + SN + + +G +P N+V SL+ E PW+ G + R+ AE+ L+ N G FLIR S+ DY++ V+ + V+ Y + + N G+ + F ++ EL+++Y+ ++DGLC L K E+P + L Y + I I+L ++G G F EV QG + + T+VAVK LK +K F E +M +L H +L+ + S E +YIITE M +GSL++YLR +K + + A +GM YLE +HRDLAARNIL+ V KV+DFGLAR+ + D+ G ++P+KWTAPEA+ ++++ KSDVWSFGILL+E+ ++GR PYP + V + L GYRM P++ P Y +M +CW + E+RPTF
Sbjct: 2 VALYDYDGRTNEDLSFKEGELLEVTDKTNSDWWYAQKKTASTSNERYNTRGYIPANYVAEYQSLDAE-PWFFGDIKRADAEKYLLADVNTTGAFLIRQSESRKTDYSLSVRDGSTVKHYRIRQLDENGGFFISRRVTFQNLIELVQYYKSNSDGLCMALQKPCVVIEAPTTIGLSYNTVDKWEIPRASIQLQKRLGAGMFGEVWQGLWNNSTLVAVKTLKP--GAMKKEEFIGEAQIMKQLRHANLIQLYAVCSQEEPIYIITELMRHGSLLDYLRGPLGKQLKAPELVDMARQIAAGMAYLESQNYIHRDLAARNILVGEGKVCKVADFGLARI----------------------------------------IKVRYEDEYEGKAGAKVPIKWTAPEAVNFHRFSVKSDVWSFGILLYELITYGRMPYPEMGNMEVLKQLDRGYRMPQPDNCPPLFYSIMLECWNKKEEERPTF 435
BLAST of Tyrosine-protein kinase vs. Ensembl Sea Lamprey
Match: clul1 (clusterin-like 1 (retinal) [Source:ZFIN;Acc:ZDB-GENE-031118-57]) HSP 1 Score: 254.218 bits (648), Expect = 1.844e-78 Identity = 162/490 (33.06%), Postives = 243/490 (49.59%), Query Frame = 1
Query: 70 FLTALYNFEGQKAEDLPFSKGEKLKVLK-------IISDPNWITC-SNNKQHQGLVPVNHVKLSPSLNIEDPWYHGKVSRSLAEERLMPCEN--GTFLIRSSDKFPGDYTIC------VKFNDVQFYHVI-YSNKGYTLDEDSWFASMPELIEHYQKDADGLCCTLTKCYESPKSRLDYLDENVLNIKFEEIKLGPKIGCGEFSEVLQGEYQDTV-VAVKCLKKPINFAEKTLFTFEFSLMAKLNHPHLVTFKGISSSNESVYIITEYMENGSLVNYLRSRGRTVIKTNDQIKFAIDSCSGMCYLEEHCLVHRDLAARNILLNAKLVAKVSDFGLARVDDXXXXXXXXXXXXXXXXXXXXXKTPSPKLMLNVVNDLVSLPTSSVDDNTTSV---GRIPVKWTAPEALTHNKYTNKSDVWSFGILLWEIFSFGRTPYPRIYANNVKQHLLNGYRMESPEDTPNDIYELMRDCWALEPEKRPTFCEIHKILH 1476
ALY+++ + +DL F KGEK +++ + + +W S + ++G +P N+V + S+ E+ WY GKVSR AE +L+ N GTFLIR S+ G Y++ VK ++V+ Y + N GY + + F ++ +L++HY + ADGLC LT + K + L + + + +KL K+G G F EV G + T VA+K LK E F E +M KL H LV + S E +YI+TE+M GSL+++L+ +K + A +GM Y+E +HRDL A NIL+ L+ K++DFGLAR+ ++DN + + P+KWTAPEA ++T KSDVWSFGILL E+ + GR PYP + V + + GYRM P P ++ELM CW +PE+RPTF + L
Sbjct: 17 LFVALYDYDARTQDDLSFRKGEKFQIINNTIEVAVVYREGDWWEARSLSTGNKGYIPSNYVAPADSVQAEE-WYFGKVSRKDAERQLLCPGNPRGTFLIRESETTKGAYSLSIRDWDEVKGDNVKHYKIRKLDNGGYYITTRAQFDTLQKLVQHYSEHADGLCYKLTLVCPNEKPQTQGLARDAWEMPRDSLKLELKLGQGCFGEVWAGTWNGTTKVAIKTLKPGTMSPEA--FLEEAQIMKKLRHDKLVQLYAVVS-EEPIYIVTEFMSKGSLLDFLKEGDGRYLKLPQLVDMAAQIAAGMAYIERMNYIHRDLRAANILVGDNLICKIADFGLARL---------------------------------------------IEDNEYTARQGAKFPIKWTAPEAAMFGRFTIKSDVWSFGILLTELVTKGRVPYPGMVNREVLEQVERGYRMPCPPSCPESLHELMMQCWKKDPEERPTFEYLQAFLE 457
BLAST of Tyrosine-protein kinase vs. Ensembl Sea Lamprey
Match: hck (HCK proto-oncogene, Src family tyrosine kinase [Source:ZFIN;Acc:ZDB-GENE-090313-72]) HSP 1 Score: 252.292 bits (643), Expect = 2.817e-77 Identity = 160/484 (33.06%), Postives = 256/484 (52.89%), Query Frame = 1
Query: 64 GDFLTALYNFEGQKAEDLPFSKGEKLKVLKIISDPNWITCSNNKQHQGLVPVNHVKLSPSLNIEDPWYHGKVSRSLAEERLMPCEN--GTFLIRSSDKFPGDYTICVKFNDVQFYHVIYSNKGYTLDEDSWFAS-------MPELIEHYQKDADGLCCTLTKCYESPKSRLDYLDENVLNIKFEEIKLGPKIGCGEFSEVLQGEY-QDTVVAVKCLKKPINFAEKTLFTFEFSLMAKLNHPHLVTFKGISSSNESVYIITEYMENGSLVNYLRSRGRTVIKTNDQIKFAIDSCSGMCYLEEHCLVHRDLAARNILLNAKLVAKVSDFGLARVDDXXXXXXXXXXXXXXXXXXXXXKTPSPKLMLNVVNDLVSLPTSSVDDNTTSV---GRIPVKWTAPEALTHNKYTNKSDVWSFGILLWEIFSFGRTPYPRIYANNVKQHLLNGYRMESPEDTPNDIYELMRDCWALEPEKRPTFCEIHKILH 1476
G + ALY+++ A+DL F +G++L +++ +D W S + +G +P N V S+ E+ W+ +SR AE +L+ C N G++LIR S+ G Y++ V+ + V+ + K TLD+ +F + + EL+ +Y ADGLC L K + + + + +++ I E IKL K+G G+F +V G Y + T VAVK +K P + A + F E +LM L H LV + + +E ++I+TEYME GSL+++L++ + +K I GM ++E+ +HRDL A NIL+N LV K++DFGLAR+ ++DN + + P+KWTAPEA+ + ++ KSDVWSFGILL E+ +FGR PYP + V + L GYRM P++ P ++Y +M++CW +PE+RPTF + +L
Sbjct: 65 GLLVVALYDYDPIHADDLCFRRGDQLVIVEEGND-WWKARSVATKKEGYIPSNFVAKVNSIEKEE-WFFKGLSRKDAERQLLLCGNKIGSYLIRDSETNKGSYSLSVRDHIVEVGDTVKHYKIRTLDKGGYFITSRITFHTLQELVVYYHLKADGLCQKLGKPCIAIQPQKPW-EKDAWEIPRESIKLEKKLGAGQFGDVWMGVYNKKTKVAVKMMK-PGSMAPQA-FLEEANLMKTLQHDKLVRLHAVVT-DEPIFIVTEYMEKGSLLDFLKTSEGSRLKQPKMIDMCAQVAEGMAFIEDKNYIHRDLRAANILVNVNLVCKIADFGLARI---------------------------------------------IEDNEYTAREGAKFPIKWTAPEAINYGSFSIKSDVWSFGILLTEMVTFGRIPYPGMTNPEVIRSLERGYRMPKPDNCPCELYSIMQECWRQKPEERPTFEYLQSLLE 497
BLAST of Tyrosine-protein kinase vs. Ensembl Sea Lamprey
Match: abl1 (c-abl oncogene 1, non-receptor tyrosine kinase [Source:ZFIN;Acc:ZDB-GENE-100812-9]) HSP 1 Score: 251.521 bits (641), Expect = 5.767e-73 Identity = 165/495 (33.33%), Postives = 246/495 (49.70%), Query Frame = 1
Query: 28 TKEFLLHMPLKPGD--FLTALYNFEGQKAEDLPFSKGEKLKVLKIISDPNWITCSNNKQHQGLVPVNHVKLSPSLNIEDPWYHGKVSRSLAEERLMPCENGTFLIRSSDKFPGDYTICVKFNDVQFYHVI--YSNKGYTLDEDSWFASMPELIEHYQKDADGLCCTLTKCYESPKSRLDYL-----DENVLNIKFEEIKLGPKIGCGEFSEVLQG---EYQDTVVAVKCLKKPINFAEKTLFTFEFSLMAKLNHPHLVTFKGISSSNESVYIITEYMENGSLVNYLRSRGRTVIKTNDQIKFAIDSCSGMCYLEEHCLVHRDLAARNILLNAKLVAKVSDFGLARVDDXXXXXXXXXXXXXXXXXXXXXKTPSPKLMLNVVNDLVSLPTSSVDDNTTSVG-RIPVKWTAPEALTHNKYTNKSDVWSFGILLWEIFSFGRTPYPRIYANNVKQHLLNGYRMESPEDTPNDIYELMRDCWALEPEKRPTFCEIHKIL 1473
+KE LL +P P D ALY+F L +KGEKL+VL + W +++ QG VP N++ SL WYHG +SR+ AE L NG+FL+R S+ PG +I ++ +++ I S+ Y + +S F+++ EL+ H+ ADGL L Y +PK + + I+ +I + K+G G++ EV +G +Y TV AVK L + E F E ++M ++ HP+LV G+ + YI+TE+M +G+L++YLR R + + A S M YLE+ +HRDLAARN L+ + KV+DFGL+R LM D T G + P+KWTAPE+L +NK+ +FG+LLWEI ++G +PYP + + V + L GYRME PE P +Y+LM+ CW RP+F EIH+
Sbjct: 24 SKENLLSVPGDPDDTNLFVALYDFVASGDNTLSITKGEKLRVLGYNQNGEWCEV-HSRNGQGWVPSNYITPVNSLEKHS-WYHGPISRNAAEYLLSSGINGSFLLRESESSPGQLSISLRCEGRVYHYRINTASDGKYFVSSESRFSTLAELVHHHSSVADGLIVPLH--YPAPKRTKPTVYGVSPTYDRWEIERTDITMKHKLGGGQYGEVYEGLKKKYSRTV-AVKTLNPREDTMEVEEFLKEAAMMKEIKHPNLVQLLGVCTREPPFYIVTEFMTHGNLLDYLRECNRDEVTAVVLLHMATQISSAMEYLEKKNFIHRDLAARNCLVAESHMVKVADFGLSR------------------------------LMTG-------------DTYTARAGAKFPIKWTAPESLAYNKFCAPVSCSAFGVLLWEIATYGMSPYPGVDLSQVYERLERGYRMEQPEGCPPRVYQLMQACWQWNAADRPSFAEIHQTF 470
BLAST of Tyrosine-protein kinase vs. Ensembl Yeast
Match: CMK1 (Calmodulin-dependent protein kinase; may play a role in stress response, many Ca++/calmodulin dependent phosphorylation substrates demonstrated in vitro, amino acid sequence similar to mammalian Cam Kinase II; CMK1 has a paralog, CMK2, that arose from the whole genome duplication [Source:SGD;Acc:S000001910]) HSP 1 Score: 77.0258 bits (188), Expect = 1.509e-15 Identity = 75/306 (24.51%), Postives = 121/306 (39.54%), Query Frame = 1
Query: 598 LGPKIGCGEFSEVLQGEYQDTV--VAVKCL-KKPINFAEKTLFTF--EFSLMAKLNHPHLVTFKGISSSNESVYIITEYMENGSLVNYLRSRGRTVIKTNDQIKFAIDSCSGMCYLEEHCLVHRDLAARNILLNAK-----LVAKVSDFGLARVDDXXXXXXXXXXXXXXXXXXXXXKTPSPKLMLNVVNDLVSLPTSSVDDNTTSVGRIPVKWTAPEALTHNKYTNKSDVWSFGILLWEIFSFGRTPYPRIYANNVKQHLLNGYRMESP--------EDTPNDIYELMRDCWALEPEKRPTFCEI 1461
G +G G F V Q + +T VAVK L KK + + L E ++ +L+HP++V FK S + YIIT+ + G L + + +G+ D ++ ++ S + Y+ +VHRDL N+L K LV V+DFG+A+ L +L+ P S+ + APE LT + + D+WS G++ + + Y A V+ L E P + N + + L+P KRPT E+
Sbjct: 39 FGKTLGAGTFGVVRQAKNTETGEDVAVKILIKKALKGNKVQLEALYDELDILQRLHHPNIVAFKDWFESKDKFYIITQLAKGGELFDRILKKGK--FTEEDAVRILVEILSAVKYMHSQNIVHRDLKPENLLYIDKSDESPLV--VADFGIAK-------------------------------RLKSDEELLYKPAGSLG------------YVAPEVLTQDGHGKPCDIWSIGVITYTLL----CGYSAFRAERVQDFLDECTTGEYPVKFHRPYWDSVSNKAKQFILKALNLDPSKRPTAAEL 293
BLAST of Tyrosine-protein kinase vs. Ensembl Yeast
Match: CDC15 (Protein kinase of the Mitotic Exit Network; localized to the spindle pole bodies at late anaphase; promotes mitotic exit by directly switching on the kinase activity of Dbf2p; required for spindle disassembly after meiosis II; relocalizes to the cytoplasm upon DNA replication stress [Source:SGD;Acc:S000000072]) HSP 1 Score: 78.1814 bits (191), Expect = 1.630e-15 Identity = 73/292 (25.00%), Postives = 120/292 (41.10%), Query Frame = 1
Query: 598 LGPKIGCGEFSEVLQG--EYQDTVVAVKCLKKPINFAEKTLFTFEFSLMAKLNHPHLVTFKGISSSNESVYIITEYMENGSLVNYLRSRGRTVIKTNDQIKFAIDSCSGMCYLEEHCLVHRDLAARNILLNAKLVAKVSDFGLARVDDXXXXXXXXXXXXXXXXXXXXXKTPSPKLMLNVVNDLVSLPTSSVDDNTTSVGRIPVKWTAPEALTHNKYTNKSDVWSFGILLWEIFSFGRTPYPRIYANNVKQHLLNGYRMESPEDTPNDIYELMRDCWALEPEKRPTFCEIHK 1467
L IG G + V + ++ D VVA+K + N E E SL+ LNH ++V + G + +YI+ EY NGSL L SR T + N+ + + G+ YL ++HRD+ A NILL+A K++DFG++ + V + ++L + + W APE L + + SD+WS G + E+ + PY + N+ + N P + + + C+ KRPT ++ K
Sbjct: 27 LKQVIGRGSYGVVYKAINKHTDQVVAIKEVVYE-NDEELNDIMAEISLLKNLNHNNIVKYHGFIRKSYELYILLEYCANGSL-RRLISRSSTGLSENESKTYVTQTLLGLKYLHGEGVIHRDIKAANILLSADNTVKLADFGVSTI---------------------------------VNSSALTLAGT-------------LNWMAPEILGNRGASTLSDIWSLGATVVEMLT-KNPPYHNLTDANIYYAVEND-TYYPPSSFSEPLKDFLSKCFVKNMYKRPTADQLLK 268
BLAST of Tyrosine-protein kinase vs. Ensembl Yeast
Match: KIN1 (Serine/threonine protein kinase involved in regulation of exocytosis; localizes to the cytoplasmic face of the plasma membrane; KIN1 has a paralog, KIN2, that arose from the whole genome duplication [Source:SGD;Acc:S000002529]) HSP 1 Score: 77.7962 bits (190), Expect = 1.911e-15 Identity = 67/271 (24.72%), Postives = 120/271 (44.28%), Query Frame = 1
Query: 652 QDTVVAVKCLKKPINFAEKTLFTFEFSLMAKLNHPHLVTFKGISSSNESVYIITEYMENGSLVNYLRSRGRTVIKTNDQIKFAIDSCSGMCYLEEHCLVHRDLAARNILLNAKLVAKVSDFGLARVDDXXXXXXXXXXXXXXXXXXXXXKTPSPKLMLNVVNDLVSLPTSSVDDNTTSVGRIPVKWTAPEALTHNKYTN-KSDVWSFGILLWEIFSFGRTPYPRIYANNVKQHLLNGYRMESPEDTPNDIYELMRDCWALEPEKRPTFCEI 1461
QD + K L+K I+ ++T+ E SL L HPH+ + + + Y++ EY+ G L++Y+ G I+ + KFA S + YL + +VHRDL NI+++ K+ DFGL+ + D S K + L + APE L N YT + DVWSFG++L+ + G+ P+ ++ + + + G ++E P+ ++ L+ ++P++R T ++
Sbjct: 172 QDVLERQKKLEKEISRDKRTIR--EASLGQILYHPHICRLFEMCTLSNHFYMLFEYVSGGQLLDYIIQHGS--IREHQARKFARGIASALIYLHANNIVHRDLKIENIMISDSSEIKIIDFGLSNIYD------------------------SRKQLHTFCGSLY--------------------FAAPELLKANPYTGPEVDVWSFGVVLF-VLVCGKVPFDDENSSVLHEKIKQG-KVEYPQHLSIEVISLLSKMLVVDPKRRATLKQV 392
BLAST of Tyrosine-protein kinase vs. Ensembl Yeast
Match: SSK2 (MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway; interacts with Ssk1p, leading to autophosphorylation and activation of Ssk2p which phosphorylates Pbs2p; also mediates actin cytoskeleton recovery from osmotic stress; a HOG-independent function of Ssk2p mediates the calcium-sensitive phenotype of the ptp2 msg5 double disruptant; SSK2 has a paralog, SSK22, that arose from the whole genome duplication [Source:SGD;Acc:S000005314]) HSP 1 Score: 78.1814 bits (191), Expect = 2.017e-15 Identity = 74/297 (24.92%), Postives = 128/297 (43.10%), Query Frame = 1
Query: 610 IGCGEFSEVLQGEYQDT--VVAVKCLKKPINFAEKTLFTF---EFSLMAKLNHPHLVTFKGISSSNESVYIITEYMENGSLVNYLRSRGRTVIKTNDQIKFAIDSCSGMCYLEEHCLVHRDLAARNILLNAKLVAKVSDFGLAR--VDDXXXXXXXXXXXXXXXXXXXXXKTPSPKLMLNVVNDLVSLPTSSVDDNTTSVGRIPVKWTAPEALTHNKYTNK---SDVWSFGILLWEIFSFGRTPYPRIYAN-NVKQHLLNGYRMESP--EDTPNDIYELMRDCWALEPEKRPTFCEI 1461
IG G F V D ++AVK + + + + +F E S++ LNHP++V++ G+ + V I EY E GSL L GR + Q+ + + G+ YL E +VHRD+ NILL+ V K DFG A+ ++ + + K + N N L+ + + + + APE++T + K DVWS G ++ E+ + GR P+ + + H+ G+ + P ++ + + + C P KR + E+
Sbjct: 1272 IGGGTFGRVYSAVDLDNGEILAVKEINIQDSKSMQKIFPLIKEEMSVLEILNHPNIVSYYGVEVHRDKVNIFMEYCEGGSLAALLE-HGRIEDEMVTQV-YTLQLLEGLAYLHESGIVHRDVKPENILLDFNGVIKYVDFGAAKKIANNGTRLASMNKIENADGEHEDVTHVSDSKAVKNNENALLDMMGTPM-------------YMAPESITGSTTKGKLGADDVWSLGCVVLEMIT-GRRPWANLDNEWAIMYHVAAGHTPQFPTKDEVSSAGMKFLERCLIQNPSKRASAVEL 1552
BLAST of Tyrosine-protein kinase vs. Ensembl Yeast
Match: BCK1 (MAPKKK acting in the protein kinase C signaling pathway; the kinase C signaling pathway controls cell integrity; upon activation by Pkc1p phosphorylates downstream kinases Mkk1p and Mkk2p; MAPKKK is an acronym for mitogen-activated protein (MAP) kinase kinase kinase [Source:SGD;Acc:S000003631]) HSP 1 Score: 77.0258 bits (188), Expect = 3.724e-15 Identity = 83/312 (26.60%), Postives = 131/312 (41.99%), Query Frame = 1
Query: 601 GPKIGCGEFS------EVLQGEYQDTVVAVKCLKKP--INFAEKTLFTFE-----FSLMAKLNHPHLVTFKGISSSNESVYIITEYMENGSLVNYLRSRGR---TVIKTNDQIKFAIDSCSGMCYLEEHCLVHRDLAARNILLNAKLVAKVSDFGLARVDDXXXXXXXXXXXXXXXXXXXXXKTPSPKLMLNVVNDLVSLPTSSVDDNTTSVGRIPVKWTAPEAL-THNKYTNKSDVWSFGILLWEIFSFGRTPYPRIYANNVKQHLLNGYRMES----PEDTPNDIYELMRD----CWALEPEKRPTFCEI 1461
G IG G F V GE ++AVK ++ P + E L T E S + L+H ++V + G + N + EY+ GS+ + +R GR +IK G+ YL ++HRD+ A N+LL+ + K+SDFG++R D+ S N+ R V W APE + T Y+ K D+WS G ++ E+F+ G+ P+ + V + + +S PEDT I ++ R+ C+ + PEKRPT E+
Sbjct: 1178 GEMIGKGSFGAVYLCLNVTTGE----MMAVKQVEVPKYSSQNEAILSTVEALRSEVSTLKDLDHLNIVQYLGFENKNNIYSLFLEYVAGGSVGSLIRMYGRFDEPLIK-----HLTTQVLKGLAYLHSKGILHRDMKADNLLLDQDGICKISDFGISRKS----------------------------------KDIYS--------NSDMTMRGTVFWMAPEMVDTKQGYSAKVDIWSLGCIVLEMFA-GKRPWSNL---EVVAAMFKIGKSKSAPPIPEDTLPLISQIGRNFLDACFEINPEKRPTANEL 1434
BLAST of Tyrosine-protein kinase vs. Ensembl Nematostella
Match: EDO47195 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RN18]) HSP 1 Score: 191.045 bits (484), Expect = 1.963e-56 Identity = 111/307 (36.16%), Postives = 160/307 (52.12%), Query Frame = 1
Query: 577 IKFEEIKLGPKIGCGEFSEVLQGEYQ--DTVVAVKCLKKPINFAEKTLFTFEFSLMAKLNHPHLVTFKGISSSNESVYIITEYMENGSLVNYLRSRGRTVIKTNDQIKFAIDSCSGMCYLEEHCLVHRDLAARNILLNAKLVAKVSDFGLARVDDXXXXXXXXXXXXXXXXXXXXXKTPSPKLMLNVVNDLVSLPTSSVDDNTTSVGRIPVKWTAPEALTHNKYTNKSDVWSFGILLWEIFSFGRTPYPRIYANNVKQHLLNGYRMESPEDTPNDIYELMRDCWALEPEKRPTFCEIHKILHKKMKS 1491
I+ EI + K+G G++ EV +G ++ + VAVK L++ E+ F E S+M + H +LV G+ + YIITE+M NG+L++YLRS + + A S M YLE +HRDLAARN L+ + KV+DFGL+R+ V D+ + + + P+KWTAPEAL HN ++ KSDVW+FGILLWE+ ++G +PYP I + V L GYRM PE P ++Y LM+ CW +P RP+F EIH+ L+ S
Sbjct: 9 IERTEIAMKHKLGGGQYGEVYEGTWKKYNKTVAVKTLREETMEVEE--FLKEASVMKGIKHQNLVQLLGVCTREPPFYIITEFMMNGNLLDYLRSPKGKDLDAVTLMYMATQVGSAMSYLESMNFIHRDLAARNCLVGDNNLVKVADFGLSRL---------------------------------VSEDIYTAHQGA---------KFPIKWTAPEALAHNTFSIKSDVWAFGILLWELATYGMSPYPGIDLSQVYDKLDGGYRMPCPEGCPPEVYSLMQTCWCWDPNSRPSFKEIHEKLNTMFPS 271
BLAST of Tyrosine-protein kinase vs. Ensembl Nematostella
Match: EDO33736 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SRD7]) HSP 1 Score: 192.971 bits (489), Expect = 6.858e-56 Identity = 113/311 (36.33%), Postives = 162/311 (52.09%), Query Frame = 1
Query: 577 IKFEEIKLGPKIGCGEFSEVLQG-----EYQDTVVAVKCLKKPINFAEKTLFTFEFSLMAKLNHPHLVTFKGISSSNESVYIITEYMENGSLVNYLRSR-GRTVIKTNDQIKFAIDSCSGMCYLEEHCLVHRDLAARNILLNAKLVAKVSDFGLARVDDXXXXXXXXXXXXXXXXXXXXXKTPSPKLMLNVVNDLVSLPTSSVDDNTTSVGRIPVKWTAPEALTHNKYTNKSDVWSFGILLWEIFSFGRTPYPRIYANNVKQHLLNGYRMESPEDTPNDIYELMRDCWALEPEKRPTFCEIHKILHKKMKS 1491
I +++KL IG GEF++V +G + VAVK LK + + F E S+M + +HP+++ KG+ + + IITE++ENGSL N+L+S GR + T + +GM YL E +HRDLAARNIL++ L AKVSDFGL+R +L P + + T G+IPV+WTAPEA+ + K+++ SDVWS+GILLWEI SFG PY V + GYR+ +P P I+ LM DCW E RP F +I + + ++S
Sbjct: 22 INKDDLKLEIIIGGGEFADVYRGVLTNEDKTQEKVAVKILKPGSSHKNREDFCVEASIMGQFDHPNVIALKGVITRTRPMMIITEFLENGSLDNFLKSNDGR--LTTLQLVGIGRGVAAGMAYLSEMNFIHRDLAARNILVSDNLAAKVSDFGLSR-------------------------------------ELDDSPENEQSEYQTQGGKIPVRWTAPEAIRYRKFSSASDVWSYGILLWEIMSFGERPYWTWDNFQVMDRVEGGYRLPAPMKCPKVIHNLMLDCWDKEKTSRPKFADIVRRFDEVIRS 293
BLAST of Tyrosine-protein kinase vs. Ensembl Nematostella
Match: EDO28980 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T4Y3]) HSP 1 Score: 177.178 bits (448), Expect = 9.676e-51 Identity = 98/260 (37.69%), Postives = 138/260 (53.08%), Query Frame = 1
Query: 715 FTFEFSLMAKLNHPHLVTFKGISSSNESVYIITEYMENGSLVNYLRSR-GRTVIKTNDQIKFAIDSCSGMCYLEEHCLVHRDLAARNILLNAKLVAKVSDFGLARVDDXXXXXXXXXXXXXXXXXXXXXKTPSPKLMLNVVNDLVSLPTSSVDDNTTSVGRIPVKWTAPEALTHNKYTNKSDVWSFGILLWEIFSFGRTPYPRIYANNVKQHLLNGYRMESPEDTPNDIYELMRDCWALEPEKRPTFCEIHKILHKKMKS 1491
F E S+M + +HP+++ KG+ + + IITE++ENGSL N+L+S GR + T + +GM YL E +HRDLAARNIL++ L AKVSDFGL+R +L P + + T G+IPV+WTAPEA+ + K+++ SDVWS+GILLWEI SFG PY V + GYR+ +P P I+ LM DCW E RP F +I + L + ++S
Sbjct: 10 FCVEASIMGQFDHPNVIALKGVITRTRPMMIITEFLENGSLDNFLKSNDGR--LTTLQLVGIGRGVAAGMAYLSEMNFIHRDLAARNILVSDNLAAKVSDFGLSR-------------------------------------ELDDSPENEQSEYQTQGGKIPVRWTAPEAIRYRKFSSASDVWSYGILLWEIMSFGERPYWTWDNFQVMDRVEGGYRLPAPMKCPKVIHNLMLDCWDKEKTSRPKFADIVRRLDEVIRS 230
BLAST of Tyrosine-protein kinase vs. Ensembl Nematostella
Match: EDO49126 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RGW8]) HSP 1 Score: 172.555 bits (436), Expect = 6.564e-49 Identity = 108/327 (33.03%), Postives = 152/327 (46.48%), Query Frame = 1
Query: 577 IKFEEIKLGPKIGCGEFSEVLQG---------EYQDTVVAVKCLKKPINFAEKTLFTFEFSLMAKLN-HPHLVTFKGISSSNESVYIITEYMENGSLVNYLRS-----------RGRT---VIKTNDQIKFAIDSCSGMCYLEEHCLVHRDLAARNILLNAKLVAKVSDFGLARVDDXXXXXXXXXXXXXXXXXXXXXKTPSPKLMLNVVNDLVSLPTSSVDDNTTSVGRIPVKWTAPEALTHNKYTNKSDVWSFGILLWEIFSFGRTPYPRIYANNVKQHLLNGYRMESPEDTPNDIYELMRDCWALEPEKRPTFCEIHKILHKKM 1485
+ + I G +G G F +V + E ++TVVAVK L ++ F E +M +L H ++V+ G + + +ITEY G L NYLR+ GR + ND + FA GM YL + VHRDLAARNIL+ + K+SDFGL R + SS + G++P+KW APEA+ N +T KSDVW+FG++LWEI + G +PYP + L NGYRME P+ ++Y +MR CWA PE RPTF ++ L + M
Sbjct: 13 VDYSSIAFGEVVGSGAFGKVTKATIVGLPGGPENKETVVAVKKLNAMATMEDRRNFLSEIEMMKQLGKHLNIVSILGCVTHAGQLCLITEYCPYGDLRNYLRAIRDKVSTRDSLAGRAPGRELTQNDLLSFARQIAVGMEYLSQKMFVHRDLAARNILICEDNLVKISDFGLTR----------------------------------------DVYESSEYHKMHNTGKLPLKWMAPEAIFQNVHTTKSDVWAFGVVLWEIVTLGGSPYPGQSGKEFYKKLKNGYRMEKPDMCSPELYAMMRSCWASSPEDRPTFTKLRNQLEQLM 299
BLAST of Tyrosine-protein kinase vs. Ensembl Nematostella
Match: EDO33731 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SRD2]) HSP 1 Score: 169.474 bits (428), Expect = 1.297e-48 Identity = 100/276 (36.23%), Postives = 144/276 (52.17%), Query Frame = 1
Query: 568 VLNIKFEEIKLGPKIGCGEFSEVLQG-----EYQDTVVAVKCLKKPINFAEKTLFTFEFSLMAKLNHPHLVTFKGISSSNESVYIITEYMENGSLVNYLRSR-GRTVIKTNDQIKFAIDSCSGMCYLEEHCLVHRDLAARNILLNAKLVAKVSDFGLARVDDXXXXXXXXXXXXXXXXXXXXXKTPSPKLMLNVVNDLVSLPTSSVDDNTTSVGRIPVKWTAPEALTHNKYTNKSDVWSFGILLWEIFSFGRTPYPRIYANNVKQHLLNGYRMESP 1377
+ I +++KL IG GEF++V +G + VAVK LK + + F E S+M + +HP+++ KG+ + + IITE++ENGSL N+L+S GR + T + +GM YL E +HRDLAARNIL++ L AKVSDFGL+R +L P + + T G+IPV+WTAPEA+ + K+++ SDVWS+GILLWEI SFG PY V + GYR+ +P
Sbjct: 22 AMEINKDDLKLEIIIGGGEFADVYRGVLTNEDKTQEKVAVKILKPGSSHKNREDFCVEASIMGQFDHPNVIALKGVITRTRPMMIITEFLENGSLDNFLKSNDGR--LTTLQLVGIGRGVAAGMAYLSEMNFIHRDLAARNILVSDNLAAKVSDFGLSR-------------------------------------ELDDSPENEQSEYQTQGGKIPVRWTAPEAIRYRKFSSASDVWSYGILLWEIMSFGERPYWTWDNFQVMDRVEGGYRLPAP 258
BLAST of Tyrosine-protein kinase vs. Ensembl Medaka
Match: ENSORLT00000006131.2 (tyrosine-protein kinase CSK [Source:NCBI gene;Acc:101158271]) HSP 1 Score: 370.548 bits (950), Expect = 6.149e-123 Identity = 201/490 (41.02%), Postives = 274/490 (55.92%), Query Frame = 1
Query: 52 PLKPGDFLTALYNFEGQKAEDLPFSKGEKLKVLKIISDPNWITCSNNKQHQGLVPVNHVKLSPSLNIED-----PWYHGKVSRSLAEERLMPCENGTFLIRSSDKFPGDYTICVKFND-VQFYHVIYSNKGYTLDEDSWFASMPELIEHYQKDADGLCCTLTK--CYESPKSRLDYLDENVLNIKFEEIKLGPKIGCGEFSEVLQGEYQDTVVAVKCLKKPINFAEKTLFTFEFSLMAKLNHPHLVTFKG-ISSSNESVYIITEYMENGSLVNYLRSRGRTVIKTNDQIKFAIDSCSGMCYLEEHCLVHRDLAARNILLNAKLVAKVSDFGLARVDDXXXXXXXXXXXXXXXXXXXXXKTPSPKLMLNVVNDLVSLPTSSVDDNTTSVGRIPVKWTAPEALTHNKYTNKSDVWSFGILLWEIFSFGRTPYPRIYANNVKQHLLNGYRMESPEDTPNDIYELMRDCWALEPEKRPTFCE----IHKILHKK 1482
P G A Y+F+G +DLPF+KG+ L ++ + DPNW N +G +P N+V+ + + PW+HGK++R AE L P E G FL+R S FPGDYT+CV + V+ Y +IY N T+DE+ +F ++ +L+EHY KDADGLC L K E + D + ++ +++KL IG GEF +V+ G+Y+ T VAVKC+K N A F E S+M ++ H +LV G I N S+YI+TEYM G LV+YLRSRGRTV+ +KFAID C M YLE + VHRDLAARN+L++ +AKVSDFGL + SS D ++PVKWTAPEAL ++ KSDVWS+GILLWEI+SFGR PYPRI +V + GY+M+ P+ P +Y +M+ CW L+P RP+F +H I HKK
Sbjct: 7 PWPQGTECVARYSFKGTSEQDLPFNKGDILTIIVVTKDPNWYKAKNAAGQEGTIPANYVQKREGVKTDGKLSLMPWFHGKITRDQAERLLNPPETGLFLVRESTNFPGDYTLCVSCDGKVEHYRIIYHNGKLTIDEEVYFENLMQLMEHYTKDADGLCTKLIKPKLEEGTVAAQDEFSRSGWSMNRKDLKLQQVIGKGEFGDVMVGDYRGTKVAVKCIK---NDATAQAFIAEASVMTQMRHNNLVQLLGVIVEENGSLYIVTEYMAKGCLVDYLRSRGRTVLGGEALLKFAIDVCEAMAYLETNNFVHRDLAARNVLVSDDNIAKVSDFGLTK------------------------------------------EASSTQD----TAKLPVKWTAPEALREKNFSTKSDVWSYGILLWEIYSFGRVPYPRIPLKDVVPRVEKGYKMDCPDGCPEVVYNIMKQCWNLDPGARPSFQMLKEWLHHISHKK 447
BLAST of Tyrosine-protein kinase vs. Ensembl Medaka
Match: CSK (C-terminal Src kinase [Source:NCBI gene;Acc:101160398]) HSP 1 Score: 367.081 bits (941), Expect = 1.237e-121 Identity = 196/491 (39.92%), Postives = 277/491 (56.42%), Query Frame = 1
Query: 43 LHMPLKPGDFLTALYNFEGQKAEDLPFSKGEKLKVLKIISDPNWITCSNNKQHQGLVPVNHVKLSPSLNIED-----PWYHGKVSRSLAEERLMPCENGTFLIRSSDKFPGDYTICVKFND-VQFYHVIYSNKGYTLDEDSWFASMPELIEHYQKDADGLCCTLTK--CYESPKSRLDYLDENVLNIKFEEIKLGPKIGCGEFSEVLQGEYQDTVVAVKCLKKPINFAEKTLFTFEFSLMAKLNHPHLVTFKG-ISSSNESVYIITEYMENGSLVNYLRSRGRTVIKTNDQIKFAIDSCSGMCYLEEHCLVHRDLAARNILLNAKLVAKVSDFGLARVDDXXXXXXXXXXXXXXXXXXXXXKTPSPKLMLNVVNDLVSLPTSSVDDNTTSVGRIPVKWTAPEALTHNKYTNKSDVWSFGILLWEIFSFGRTPYPRIYANNVKQHLLNGYRMESPEDTPNDIYELMRDCWALEPEKRPTFCEIHKILHKKMK 1488
+H P G A YNF+ +DLPF KG+ L ++ + DPNW N +G +P N+V+ + PW+HGK++R AE L P E G FL+R S +PGDYT+CV + V+ Y +IY N T+DE+ +F ++ +L+EHY KDADGLC L K E + D + + +E+KL IG GEF +V+ G+Y+ T VAVKC+K N A F E S+M +L H +LV G I S+YI+TEYM GSLV+YLRSRGR+V+ + +KF++D C M YLE + VHRDLAARN+L++ +AKVSDFGL + SS+ D ++PVKWT+PEAL +++ KSDVWS+GILLWEI+SFGR PYPRI +V + GY+M++P+ P +Y+LM+ CW L+ RP+F ++L +K++
Sbjct: 4 IHAPWTSGTECVAKYNFQTANEQDLPFCKGDVLTIIGVTRDPNWYRARNTTGREGTIPANYVQKREGVKSGGKLSLMPWFHGKITREQAERLLYPPETGLFLVRESTNYPGDYTLCVSCDGKVEHYRIIYHNGKLTIDEEEYFENLMQLVEHYTKDADGLCTRLIKPKLMEGTVAAQDEFSRSGWALNRKELKLLQTIGKGEFGDVILGDYRGTRVAVKCIK---NDATAQAFIAEASVMTQLRHNNLVQLLGVIVEERGSLYIVTEYMAKGSLVDYLRSRGRSVLGGDCLLKFSLDVCEAMEYLEANNFVHRDLAARNVLVSDDNIAKVSDFGLTK------------------------------------------EASSIQDT----AKLPVKWTSPEALREKRFSTKSDVWSYGILLWEIYSFGRVPYPRIPLKDVVPRVEKGYKMDAPDGCPPVVYDLMKQCWTLDAAMRPSF----RMLREKLQ 441
BLAST of Tyrosine-protein kinase vs. Ensembl Medaka
Match: CSK (C-terminal Src kinase [Source:NCBI gene;Acc:101160398]) HSP 1 Score: 320.472 bits (820), Expect = 1.408e-104 Identity = 172/413 (41.65%), Postives = 241/413 (58.35%), Query Frame = 1
Query: 262 WYHGKVSRSLAEERLMPCENGTFLIRSSDKFPGDYTICVKFN-DVQFYHVIYSNKGYTLDEDSWFASMPELIEHYQKDADGLCCTLTK--CYESPKSRLDYLDENVLNIKFEEIKLGPKIGCGEFSEVLQGEYQDTVVAVKCLKKPINFAEKTLFTFEFSLMAKLNHPHLVTFKG-ISSSNESVYIITEYMENGSLVNYLRSRGRTVIKTNDQIKFAIDSCSGMCYLEEHCLVHRDLAARNILLNAKLVAKVSDFGLARVDDXXXXXXXXXXXXXXXXXXXXXKTPSPKLMLNVVNDLVSLPTSSVDDNTTSVGRIPVKWTAPEALTHNKYTNKSDVWSFGILLWEIFSFGRTPYPRIYANNVKQHLLNGYRMESPEDTPNDIYELMRDCWALEPEKRPTFCEIHKILHKKMK 1488
W+HGK++R AE L P E G FL+R S +PGDYT+CV + V+ Y +IY N T+DE+ +F ++ +L+EHY KDADGLC L K E + D + + +E+KL IG GEF +V+ G+Y+ T VAVKC+K N A F E S+M +L H +LV G I S+YI+TEYM GSLV+YLRSRGR+V+ + +KF++D C M YLE + VHRDLAARN+L++ +AKVSDFGL + SS+ D ++PVKWT+PEAL +++ KSDVWS+GILLWEI+SFGR PYPRI +V + GY+M++P+ P +Y+LM+ CW L+ RP+F ++L +K++
Sbjct: 2 WFHGKITREQAERLLYPPETGLFLVRESTNYPGDYTLCVSCDGKVEHYRIIYHNGKLTIDEEEYFENLMQLVEHYTKDADGLCTRLIKPKLMEGTVAAQDEFSRSGWALNRKELKLLQTIGKGEFGDVILGDYRGTRVAVKCIK---NDATAQAFIAEASVMTQLRHNNLVQLLGVIVEERGSLYIVTEYMAKGSLVDYLRSRGRSVLGGDCLLKFSLDVCEAMEYLEANNFVHRDLAARNVLVSDDNIAKVSDFGLTK------------------------------------------EASSIQDT----AKLPVKWTSPEALREKRFSTKSDVWSYGILLWEIYSFGRVPYPRIPLKDVVPRVEKGYKMDAPDGCPPVVYDLMKQCWTLDAAMRPSF----RMLREKLQ 361
BLAST of Tyrosine-protein kinase vs. Ensembl Medaka
Match: matk (megakaryocyte-associated tyrosine kinase [Source:NCBI gene;Acc:101164299]) HSP 1 Score: 301.212 bits (770), Expect = 6.423e-96 Identity = 174/470 (37.02%), Postives = 264/470 (56.17%), Query Frame = 1
Query: 103 KAEDLPFSKGEKLKVLKIISDPNWITCSNNKQ-HQGLVPVNHVKLSPSLNIED-----PWYHGKVSRSLAEERLMPCENGTFLIRSSDKFPGDYTICVKFN-DVQFYHVIYSNKGYTLDEDSWFASMPELIEHYQKDADGLCCTLTKCYESPKSRLDYLDENVLN--IKFEEIKLGPKIGCGEFSEVLQGEYQDTVVAVKCLKKPINFAEKTLFTFEFSLMAKLNHPHLVTFKGISSSNESVYIITEYMENGSLVNYLRSRGRTVIKTNDQIKFAIDSCSGMCYLEEHCLVHRDLAARNILLNAKLVAKVSDFGLARVDDXXXXXXXXXXXXXXXXXXXXXKTPSPKLMLNVVNDLVSLPTSSVDDNTTSVGRIPVKWTAPEALTHNKYTNKSDVWSFGILLWEIFSFGRTPYPRIYANNVKQHLLNGYRMESPEDTPNDIYELMRDCWALEPEKRPTFCEIHKILHKKM 1485
K +L +SKG+ L ++ + + +N +GL+ HV+ +L ++ PW+HGK+S S A +L P E+G FL+R S + PGDY +CV F+ +V Y VIY + T+D +F ++ ++IE Y K+ D + TLTK + ++ L+ + + + +++LG IG GEF V +GEY VAVK +K + F E ++M KL H +LV G+ N+ ++I+TE M G+LVN+LR+RGR+V+ + ++++D C GM YLE LVHRDLAARNIL++ AK+SDFGL +V S D ++P+KWTAPEALT K++ KSDVWS+G+LLWEIFS+GR PYP++ +V+ + GYRME+PED P ++Y LM+ CW EP +RP F ++ + L ++M
Sbjct: 19 KPGELAYSKGDVLTIVACSARKRYYRAKHNATGEEGLINATHVREREALRVDPSLSLMPWFHGKISGSEAVCQLQPAEDGLFLVRESVRHPGDYVLCVSFSGEVIHYRVIYQDNKLTIDNKQYFYNLIDMIEFYSKNKDSIATTLTKPKQKQGTKSAELELSKMGWLLDMTKLRLGGIIGEGEFGAVYEGEYVGQRVAVKTIKCDVT---AQAFLQETAVMTKLQHKNLVRLLGVIL-NKGLHIVTELMIKGNLVNFLRTRGRSVVTSIQLFRYSLDVCEGMEYLESKKLVHRDLAARNILVSDDNAAKISDFGLTKV------------------------------------------VSKEADK----AKLPIKWTAPEALTKEKFSTKSDVWSYGVLLWEIFSYGRQPYPKMSLKDVQAKVEAGYRMEAPEDCPANVYSLMKLCWEQEPRRRPGFPKLREKLEREM 438
BLAST of Tyrosine-protein kinase vs. Ensembl Medaka
Match: matk (megakaryocyte-associated tyrosine kinase [Source:NCBI gene;Acc:101164299]) HSP 1 Score: 301.212 bits (770), Expect = 6.423e-96 Identity = 174/470 (37.02%), Postives = 264/470 (56.17%), Query Frame = 1
Query: 103 KAEDLPFSKGEKLKVLKIISDPNWITCSNNKQ-HQGLVPVNHVKLSPSLNIED-----PWYHGKVSRSLAEERLMPCENGTFLIRSSDKFPGDYTICVKFN-DVQFYHVIYSNKGYTLDEDSWFASMPELIEHYQKDADGLCCTLTKCYESPKSRLDYLDENVLN--IKFEEIKLGPKIGCGEFSEVLQGEYQDTVVAVKCLKKPINFAEKTLFTFEFSLMAKLNHPHLVTFKGISSSNESVYIITEYMENGSLVNYLRSRGRTVIKTNDQIKFAIDSCSGMCYLEEHCLVHRDLAARNILLNAKLVAKVSDFGLARVDDXXXXXXXXXXXXXXXXXXXXXKTPSPKLMLNVVNDLVSLPTSSVDDNTTSVGRIPVKWTAPEALTHNKYTNKSDVWSFGILLWEIFSFGRTPYPRIYANNVKQHLLNGYRMESPEDTPNDIYELMRDCWALEPEKRPTFCEIHKILHKKM 1485
K +L +SKG+ L ++ + + +N +GL+ HV+ +L ++ PW+HGK+S S A +L P E+G FL+R S + PGDY +CV F+ +V Y VIY + T+D +F ++ ++IE Y K+ D + TLTK + ++ L+ + + + +++LG IG GEF V +GEY VAVK +K + F E ++M KL H +LV G+ N+ ++I+TE M G+LVN+LR+RGR+V+ + ++++D C GM YLE LVHRDLAARNIL++ AK+SDFGL +V S D ++P+KWTAPEALT K++ KSDVWS+G+LLWEIFS+GR PYP++ +V+ + GYRME+PED P ++Y LM+ CW EP +RP F ++ + L ++M
Sbjct: 19 KPGELAYSKGDVLTIVACSARKRYYRAKHNATGEEGLINATHVREREALRVDPSLSLMPWFHGKISGSEAVCQLQPAEDGLFLVRESVRHPGDYVLCVSFSGEVIHYRVIYQDNKLTIDNKQYFYNLIDMIEFYSKNKDSIATTLTKPKQKQGTKSAELELSKMGWLLDMTKLRLGGIIGEGEFGAVYEGEYVGQRVAVKTIKCDVT---AQAFLQETAVMTKLQHKNLVRLLGVIL-NKGLHIVTELMIKGNLVNFLRTRGRSVVTSIQLFRYSLDVCEGMEYLESKKLVHRDLAARNILVSDDNAAKISDFGLTKV------------------------------------------VSKEADK----AKLPIKWTAPEALTKEKFSTKSDVWSYGVLLWEIFSYGRQPYPKMSLKDVQAKVEAGYRMEAPEDCPANVYSLMKLCWEQEPRRRPGFPKLREKLEREM 438
BLAST of Tyrosine-protein kinase vs. Planmine SMEST
Match: SMESG000016115.1 (SMESG000016115.1) HSP 1 Score: 954.896 bits (2467), Expect = 0.000e+0 Identity = 483/483 (100.00%), Postives = 483/483 (100.00%), Query Frame = 1
Query: 49 MPLKPGDFLTALYNFEGQKAEDLPFSKGEKLKVLKIISDPNWITCSNNKQHQGLVPVNHVKLSPSLNIEDPWYHGKVSRSLAEERLMPCENGTFLIRSSDKFPGDYTICVKFNDVQFYHVIYSNKGYTLDEDSWFASMPELIEHYQKDADGLCCTLTKCYESPKSRLDYLDENVLNIKFEEIKLGPKIGCGEFSEVLQGEYQDTVVAVKCLKKPINFAEKTLFTFEFSLMAKLNHPHLVTFKGISSSNESVYIITEYMENGSLVNYLRSRGRTVIKTNDQIKFAIDSCSGMCYLEEHCLVHRDLAARNILLNAKLVAKVSDFGLARVDDXXXXXXXXXXXXXXXXXXXXXKTPSPKLMLNVVNDLVSLPTSSVDDNTTSVGRIPVKWTAPEALTHNKYTNKSDVWSFGILLWEIFSFGRTPYPRIYANNVKQHLLNGYRMESPEDTPNDIYELMRDCWALEPEKRPTFCEIHKILHKKMKSFL 1497
MPLKPGDFLTALYNFEGQKAEDLPFSKGEKLKVLKIISDPNWITCSNNKQHQGLVPVNHVKLSPSLNIEDPWYHGKVSRSLAEERLMPCENGTFLIRSSDKFPGDYTICVKFNDVQFYHVIYSNKGYTLDEDSWFASMPELIEHYQKDADGLCCTLTKCYESPKSRLDYLDENVLNIKFEEIKLGPKIGCGEFSEVLQGEYQDTVVAVKCLKKPINFAEKTLFTFEFSLMAKLNHPHLVTFKGISSSNESVYIITEYMENGSLVNYLRSRGRTVIKTNDQIKFAIDSCSGMCYLEEHCLVHRDLAARNILLNAKLVAKVSDFGLARVDDSRTNSENCNNNLNSNSKNHSSKTPSPKLMLNVVNDLVSLPTSSVDDNTTSVGRIPVKWTAPEALTHNKYTNKSDVWSFGILLWEIFSFGRTPYPRIYANNVKQHLLNGYRMESPEDTPNDIYELMRDCWALEPEKRPTFCEIHKILHKKMKSFL
Sbjct: 1 MPLKPGDFLTALYNFEGQKAEDLPFSKGEKLKVLKIISDPNWITCSNNKQHQGLVPVNHVKLSPSLNIEDPWYHGKVSRSLAEERLMPCENGTFLIRSSDKFPGDYTICVKFNDVQFYHVIYSNKGYTLDEDSWFASMPELIEHYQKDADGLCCTLTKCYESPKSRLDYLDENVLNIKFEEIKLGPKIGCGEFSEVLQGEYQDTVVAVKCLKKPINFAEKTLFTFEFSLMAKLNHPHLVTFKGISSSNESVYIITEYMENGSLVNYLRSRGRTVIKTNDQIKFAIDSCSGMCYLEEHCLVHRDLAARNILLNAKLVAKVSDFGLARVDDSRTNSENCNNNLNSNSKNHSSKTPSPKLMLNVVNDLVSLPTSSVDDNTTSVGRIPVKWTAPEALTHNKYTNKSDVWSFGILLWEIFSFGRTPYPRIYANNVKQHLLNGYRMESPEDTPNDIYELMRDCWALEPEKRPTFCEIHKILHKKMKSFL 483
BLAST of Tyrosine-protein kinase vs. Planmine SMEST
Match: SMESG000016115.1 (SMESG000016115.1) HSP 1 Score: 479.174 bits (1232), Expect = 1.356e-168 Identity = 254/254 (100.00%), Postives = 254/254 (100.00%), Query Frame = 1
Query: 736 MAKLNHPHLVTFKGISSSNESVYIITEYMENGSLVNYLRSRGRTVIKTNDQIKFAIDSCSGMCYLEEHCLVHRDLAARNILLNAKLVAKVSDFGLARVDDXXXXXXXXXXXXXXXXXXXXXKTPSPKLMLNVVNDLVSLPTSSVDDNTTSVGRIPVKWTAPEALTHNKYTNKSDVWSFGILLWEIFSFGRTPYPRIYANNVKQHLLNGYRMESPEDTPNDIYELMRDCWALEPEKRPTFCEIHKILHKKMKSFL 1497
MAKLNHPHLVTFKGISSSNESVYIITEYMENGSLVNYLRSRGRTVIKTNDQIKFAIDSCSGMCYLEEHCLVHRDLAARNILLNAKLVAKVSDFGLARVDDSRTNSENCNNNLNSNSKNHSSKTPSPKLMLNVVNDLVSLPTSSVDDNTTSVGRIPVKWTAPEALTHNKYTNKSDVWSFGILLWEIFSFGRTPYPRIYANNVKQHLLNGYRMESPEDTPNDIYELMRDCWALEPEKRPTFCEIHKILHKKMKSFL
Sbjct: 1 MAKLNHPHLVTFKGISSSNESVYIITEYMENGSLVNYLRSRGRTVIKTNDQIKFAIDSCSGMCYLEEHCLVHRDLAARNILLNAKLVAKVSDFGLARVDDSRTNSENCNNNLNSNSKNHSSKTPSPKLMLNVVNDLVSLPTSSVDDNTTSVGRIPVKWTAPEALTHNKYTNKSDVWSFGILLWEIFSFGRTPYPRIYANNVKQHLLNGYRMESPEDTPNDIYELMRDCWALEPEKRPTFCEIHKILHKKMKSFL 254
BLAST of Tyrosine-protein kinase vs. Planmine SMEST
Match: SMESG000016115.1 (SMESG000016115.1) HSP 1 Score: 411.379 bits (1056), Expect = 1.117e-142 Identity = 194/194 (100.00%), Postives = 194/194 (100.00%), Query Frame = 1
Query: 49 MPLKPGDFLTALYNFEGQKAEDLPFSKGEKLKVLKIISDPNWITCSNNKQHQGLVPVNHVKLSPSLNIEDPWYHGKVSRSLAEERLMPCENGTFLIRSSDKFPGDYTICVKFNDVQFYHVIYSNKGYTLDEDSWFASMPELIEHYQKDADGLCCTLTKCYESPKSRLDYLDENVLNIKFEEIKLGPKIGCGEFS 630
MPLKPGDFLTALYNFEGQKAEDLPFSKGEKLKVLKIISDPNWITCSNNKQHQGLVPVNHVKLSPSLNIEDPWYHGKVSRSLAEERLMPCENGTFLIRSSDKFPGDYTICVKFNDVQFYHVIYSNKGYTLDEDSWFASMPELIEHYQKDADGLCCTLTKCYESPKSRLDYLDENVLNIKFEEIKLGPKIGCGEFS
Sbjct: 1 MPLKPGDFLTALYNFEGQKAEDLPFSKGEKLKVLKIISDPNWITCSNNKQHQGLVPVNHVKLSPSLNIEDPWYHGKVSRSLAEERLMPCENGTFLIRSSDKFPGDYTICVKFNDVQFYHVIYSNKGYTLDEDSWFASMPELIEHYQKDADGLCCTLTKCYESPKSRLDYLDENVLNIKFEEIKLGPKIGCGEFS 194
BLAST of Tyrosine-protein kinase vs. Planmine SMEST
Match: SMESG000059351.1 (SMESG000059351.1) HSP 1 Score: 295.049 bits (754), Expect = 1.356e-94 Identity = 163/420 (38.81%), Postives = 234/420 (55.71%), Query Frame = 1
Query: 262 WYHGKVSRSLAEERLMPCENGTFLIRSSDKFPGDYTICVKFND-VQFYHVIYSNKG-YTLDEDSWFASMPELIEHYQKDADGLCCTLTKCYESPKSRL-------DYLDENVLNIKFEEIKLGPKIGCGEFSEVLQGEYQDTVVAVKCLKKPINFAEKTLFTF-EFSLMAKLNHPHLVTFKGISSSNESVYIITEYMENGSLVNYLRSRGRTVIKTNDQIKFAIDSCSGMCYLEEHCLVHRDLAARNILLNAKLVAKVSDFGLARVDDXXXXXXXXXXXXXXXXXXXXXKTPSPKLMLNVVNDLVSLPTSSVDDNTTSVGRIPVKWTAPEALTHNKYTNKSDVWSFGILLWEIFSFGRTPYPRIYANNVKQHLLNGYRMESPEDTPNDIYELMRDCWALEPEKRPTFCEIHKILHKKMKS 1491
WYHG ++R AE+ L P E G FLIR S +PGD+T+CV + D VQ Y +IY K YT+DE+ +F+S+ EL+E Y DA+GL LTK PKS L Y + + + L +G G+F+EV + Y ++A KC+ I ++ T E S+M + H +LV F G+ ++ +Y++TEYM NGSLVNYLR+RG++ I +Q+ F+I+ GM YLE+ LVHRDLA RNILL+ +VAK++DFGL R DS GR+P+KWTAPEA+ +N+++ SD+WSFG++LWEI+SFG+ PY I +V + G+R+ P++ P +IY LM W + P RP F + HK+L + S
Sbjct: 16 WYHGPITRETAEQLLHPREEGLFLIRESVNYPGDFTLCVCYQDGVQHYRIIYDKKQRYTIDEEEYFSSLEELVEFYISDANGLVTCLTK--PLPKSGLPIYPPVIHYFQQAGWVFPRDGLDLEECLGKGDFAEVFKAHYNGKILAAKCV---IQSSDLTFVGIKEASVMTTVRHQNLVQFHGLVIDSDKIYLLTEYMLNGSLVNYLRTRGKSGITPINQLMFSINVACGMSYLEQKDLVHRDLACRNILLDKNMVAKIADFGLCRETDSYELG----------------------------------------------GRVPIKWTAPEAVKNNQFSPMSDMWSFGVVLWEIYSFGKLPYSGISVQHVMSEIEQGFRLPCPQNCPPEIYSLMDAAWVINPAHRPNFKQAHKVLTTILNS 384
BLAST of Tyrosine-protein kinase vs. Planmine SMEST
Match: SMESG000045588.1 (SMESG000045588.1) HSP 1 Score: 246.514 bits (628), Expect = 2.324e-74 Identity = 165/490 (33.67%), Postives = 250/490 (51.02%), Query Frame = 1
Query: 73 LTALYNFEGQKAEDLPFSKGEKLKVLKIISDPNWITCSNNKQHQGLVPVNHVKL---SPSLNIEDPWYHGKVSRSLAEERLMPCEN--GTFLIRS-SDKFPGDYTICVK-FNDVQFYHVIYSNKGYTLDED--------SWFASMPELIEHYQKDADGLCCTLT-KCYESPKSRLDYLDENVLNIKFEEIKLGPKIGCGEFSEVLQGEYQDTV-VAVKCLKKPINFAEKTLFTFEFSLMAKLNHPHLVTFKGISSS--NESVYIITEYMENGSLVNYLRSRGRTVIKTNDQIKFAIDSCSGMCYLEEHCLVHRDLAARNILLNAKLVAKVSDFGLARVDDXXXXXXXXXXXXXXXXXXXXXKTPSPKLMLNVVNDLVSLPTSSVDDNTTSVGRIPVKWTAPEALTHNKYTNKSDVWSFGILLWEIFSFGRTPYPRIYANNVKQHLLNGYRMESPEDT----PNDIYELMRDCWALEPEKRPTFCEIHKIL 1473
+ AL+++E + +DL FSKG+ + + +S+ W+ + G +P N+V L SPS + + WY ++ A+++L+ N GT++IR SD Y + V+ F+ + Y+V+ K TLD + S F ++ LI++YQ + DGLCC LT C + K + + D + + + I+L +G G F EV G++ ++V VAVK LK N +++ F E LM KLNHP +V G+ + + V+IITE M NG+L+NYLRS ++ N+ + GM YLE VHRDL A NIL++ L KV+DFGLARV D N + + P+KWTAPEA +++ KSDVWSFG+L++EI ++GRTPYP I V + GYR+ +P P+++Y + CW PE RPTF + I
Sbjct: 69 VRALFSYEARHTDDLEFSKGDLMYISSDMSEAWWLALHATTKKTGYIPSNYVVLDDGSPSSH--EGWY--DITHKEADKKLLRMGNPIGTYIIRPCSDS--KHYALSVRHFDTTKNYYVVKHYKIRTLDNNLGFYISNRSKFPNISSLIKYYQTNTDGLCCKLTLSCPQRHKPPIQFKD---IEVSRDCIRLERVLGNGSFGEVYLGKWNNSVEVAVKQLKP--NSMDRSRFIAEAELMHKLNHPRIVQILGVCTQPPEQPVFIITELMANGALLNYLRSPEGQKLRLNEMLDMMSQIAEGMAYLESRNFVHRDLRAANILVDEDLSVKVADFGLARVTDDVY-------------------------------------------NADTGTKFPIKWTAPEAGMQRRFSVKSDVWSFGVLMYEIVTYGRTPYPGIPNRQVLDEVSKGYRLPNPAGGKIVCPDELYAIKLKCWDAYPENRPTFSHLQDIF 504 The following BLAST results are available for this feature:
BLAST of Tyrosine-protein kinase vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Tyrosine-protein kinase vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Tyrosine-protein kinase vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Tyrosine-protein kinase vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Tyrosine-protein kinase vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Tyrosine-protein kinase vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Tyrosine-protein kinase vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Tyrosine-protein kinase vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Tyrosine-protein kinase vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Tyrosine-protein kinase vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Tyrosine-protein kinase vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 5
BLAST of Tyrosine-protein kinase vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Tyrosine-protein kinase vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Tyrosine-protein kinase vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30017367 ID=SMED30017367|Name=Tyrosine-protein kinase|organism=Schmidtea mediterranea sexual|type=transcript|length=1731bpback to top protein sequence of SMED30017367-orf-1 >SMED30017367-orf-1 ID=SMED30017367-orf-1|Name=SMED30017367-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=500bp IYINLICSSTKEFLLHMPLKPGDFLTALYNFEGQKAEDLPFSKGEKLKVLback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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