jagunal

Overview
Namejagunal (AHY82410.1)
Smed IDSMED30017352
Length (bp)701
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of jagunal (SMED30017352) t-SNE clustered cells

Violin plots show distribution of expression levels for jagunal (SMED30017352) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of jagunal (SMED30017352) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for jagunal (SMED30017352) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30017352

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 2

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
muscle cellSMED30017352h1SMcG0013823 dd_Smed_v4_3028_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30017352h1SMcG0013823 dd_Smed_v4_3028_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of jagunal vs. Ensembl Human
Match: JAGN1 (jagunal homolog 1 [Source:HGNC Symbol;Acc:HGNC:26926])

HSP 1 Score: 98.5969 bits (244), Expect = 4.384e-25
Identity = 59/194 (30.41%), Postives = 100/194 (51.55%), Query Frame = 2 
Query:   59 MASKTGARPTGTDGSDFRHREKVANQYNISPFLKKRLRFVYSCHTIVWLIILLKFIPEIFRNLGISLEYFKSVNLPSPDTWEFVWFLGSLTPSIFGYLSLSKNRVFLLRVSLFGTMIFGFIPISVGVCYKALELY----DFYQTKVSNSNIFGLPLVVVWYIFFCGCIQIHGFSLFFGLKLLRTW-TGQLHKKN 625
            MAS+ G R  GTDGSDF+HRE+VA  Y +S  LK  ++ +   H ++WL+++ K       ++G  L       +  P  WE+ + L S+ PS+ G LS  +N +  L +S+    +F   P+     Y ++E++      Y+   +   +FG   V + Y+     +Q+H + L++  KLL +W T    KK+
Sbjct:    1 MASRAGPRAAGTDGSDFQHRERVAMHYQMSVTLKYEIKKLIYVHLVIWLLLVAKM------SVG-HLRLLSHDQVAMPYQWEYPYLL-SILPSLLGLLSFPRNNISYLVLSMISMGLFSIAPL----IYGSMEMFPAAQQLYRHGKAYRFLFGFSAVSIMYLVLVLAVQVHAWQLYYSKKLLDSWFTSTQEKKH 182
[Close]
BLAST of jagunal vs. Ensembl Human
Match: JAGN1 (jagunal homolog 1 [Source:HGNC Symbol;Acc:HGNC:26926])

HSP 1 Score: 46.9802 bits (110), Expect = 3.987e-7
Identity = 24/49 (48.98%), Postives = 28/49 (57.14%), Query Frame = 2 
Query:   59 MASKTGARPTGTDGSDFRHREKVANQYNISPFLKKRLRFV-YSCHTIVW 202
            MAS+ G R  GTDGSDF+HRE+VA  Y +  F       V YSC    W
Sbjct:    1 MASRAGPRAAGTDGSDFQHRERVAMHYQMRLFYSNLYPSVQYSCLAYSW 49
[Close]
BLAST of jagunal vs. Ensembl Celegans
Match: K05C4.2 (pep chromosome:WBcel235:I:14720597:14721979:-1 gene:WBGene00010579.1 transcript:K05C4.2.2 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:K05C4.2)

HSP 1 Score: 110.538 bits (275), Expect = 6.300e-30
Identity = 60/184 (32.61%), Postives = 99/184 (53.80%), Query Frame = 2 
Query:   65 SKTGARPTGTDGSDFRHREKVANQYNISPFLKKRLRFVYSCHTIVWLIILLKFIPEIFR-NLGISLEYFKSVNLPSPDTWEFVWFLGSLTPSIFGYLSLSKNRVFLLRVSLFGTMIFGFIPISVGVCYKALELYDFYQT-KVSNSNIFG--LPLVVVWYIFFCGCIQIHGFSLFFGLKLLRTWT 604
            S  G R  GTDG+DF++R++VA  Y  S   K  L++ +  H ++ + + LK   E+ R N G    +F  +++PS   WE+VW   S  P +    S  +N++ +L  + +   + G  P  +G+  +  EL ++ Q  + SN+  F    P+V++WYIFF   +QIHGFS++F   L   W 
Sbjct:    2 SSRGVRAAGTDGTDFQNRQRVAQHYQESAQYKSILKWFFVPHFLILVFMWLKVGSELLRTNFGWKNAFFDRLDMPSAYPWEYVWCF-SFIPIVLAIYSFQRNKLKILHYAYYAEFVVGIFPCMIGLGGQLPELMEYAQDMEGSNTPTFKGIFPMVIIWYIFFAVALQIHGFSMYFMHHLAAAWA 184
[Close]
BLAST of jagunal vs. Ensembl Celegans
Match: K05C4.2 (pep chromosome:WBcel235:I:14720588:14721355:-1 gene:WBGene00010579.1 transcript:K05C4.2.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:K05C4.2)

HSP 1 Score: 110.538 bits (275), Expect = 6.300e-30
Identity = 60/184 (32.61%), Postives = 99/184 (53.80%), Query Frame = 2 
Query:   65 SKTGARPTGTDGSDFRHREKVANQYNISPFLKKRLRFVYSCHTIVWLIILLKFIPEIFR-NLGISLEYFKSVNLPSPDTWEFVWFLGSLTPSIFGYLSLSKNRVFLLRVSLFGTMIFGFIPISVGVCYKALELYDFYQT-KVSNSNIFG--LPLVVVWYIFFCGCIQIHGFSLFFGLKLLRTWT 604
            S  G R  GTDG+DF++R++VA  Y  S   K  L++ +  H ++ + + LK   E+ R N G    +F  +++PS   WE+VW   S  P +    S  +N++ +L  + +   + G  P  +G+  +  EL ++ Q  + SN+  F    P+V++WYIFF   +QIHGFS++F   L   W 
Sbjct:    2 SSRGVRAAGTDGTDFQNRQRVAQHYQESAQYKSILKWFFVPHFLILVFMWLKVGSELLRTNFGWKNAFFDRLDMPSAYPWEYVWCF-SFIPIVLAIYSFQRNKLKILHYAYYAEFVVGIFPCMIGLGGQLPELMEYAQDMEGSNTPTFKGIFPMVIIWYIFFAVALQIHGFSMYFMHHLAAAWA 184
[Close]
BLAST of jagunal vs. Ensembl Fly
Match: jagn (gene:FBgn0037374 transcript:FBtr0078624)

HSP 1 Score: 99.3673 bits (246), Expect = 1.548e-25
Identity = 56/196 (28.57%), Postives = 99/196 (50.51%), Query Frame = 2 
Query:   59 MASKTGARPTGTDGSDFRHREKVANQYNISPFLKKRLRFVYSCHTIVWLIILLKFIPEIFRNLGISLEYFKSVNLPSPDTWEFVWFLGSLTPSIFGYLSLSKNRVFLLRVSLFGTMIFGFIPISVGVCYKALELYDFY----QTKVSNSNIF---GLPLVVVWYIFFCGCIQIHGFSLFFGLKLLRTWTGQLHKKN 625
            MA++ G    GTDG+DF  R++VA  Y IS   K RL++    H +++ ++L K   +I  +L I +   + + +P P  WE+VW   SL  S  G  +   N+V  ++  +   ++F  +P+     Y   ++++F       ++  ++IF   G P  V WY F     Q+HGF+L+F   L++ W  +   + 
Sbjct:    1 MATRGGPMVAGTDGNDFEFRQRVAGTYQISLLNKSRLKYCIFFHALLFFVMLAKLTSDILDHLDIFVLEIEELEVPPPLWWEYVW-AASLLTSFLGLSAARGNKVREMQKYMVAILLFAILPLFYCFAYYFSDVWEFATLDKSVELDETDIFVWRGYPYGVFWYAFCFVGFQVHGFTLYFAYNLVKAWKARTATRK 195
[Close]
BLAST of jagunal vs. Ensembl Fly
Match: jagn (gene:FBgn0037374 transcript:FBtr0078625)

HSP 1 Score: 99.3673 bits (246), Expect = 1.548e-25
Identity = 56/196 (28.57%), Postives = 99/196 (50.51%), Query Frame = 2 
Query:   59 MASKTGARPTGTDGSDFRHREKVANQYNISPFLKKRLRFVYSCHTIVWLIILLKFIPEIFRNLGISLEYFKSVNLPSPDTWEFVWFLGSLTPSIFGYLSLSKNRVFLLRVSLFGTMIFGFIPISVGVCYKALELYDFY----QTKVSNSNIF---GLPLVVVWYIFFCGCIQIHGFSLFFGLKLLRTWTGQLHKKN 625
            MA++ G    GTDG+DF  R++VA  Y IS   K RL++    H +++ ++L K   +I  +L I +   + + +P P  WE+VW   SL  S  G  +   N+V  ++  +   ++F  +P+     Y   ++++F       ++  ++IF   G P  V WY F     Q+HGF+L+F   L++ W  +   + 
Sbjct:    1 MATRGGPMVAGTDGNDFEFRQRVAGTYQISLLNKSRLKYCIFFHALLFFVMLAKLTSDILDHLDIFVLEIEELEVPPPLWWEYVW-AASLLTSFLGLSAARGNKVREMQKYMVAILLFAILPLFYCFAYYFSDVWEFATLDKSVELDETDIFVWRGYPYGVFWYAFCFVGFQVHGFTLYFAYNLVKAWKARTATRK 195
[Close]
BLAST of jagunal vs. Ensembl Zebrafish
Match: jagn1b (jagunal homolog 1b [Source:NCBI gene;Acc:445190])

HSP 1 Score: 102.834 bits (255), Expect = 6.208e-27
Identity = 56/185 (30.27%), Postives = 95/185 (51.35%), Query Frame = 2 
Query:   59 MASKTGARPTGTDGSDFRHREKVANQYNISPFLKKRLRFVYSCHTIVWLIILLKFIPEIFRNLGISLEYFKSVNLPSPDTWEFVWFLGSLTPSIFGYLSLSKNRVFLLRVSLFGTMIFGFIPISVGVCYKALELYDFYQTKVSNSN----IFGLPLVVVWYIFFCGCIQIHGFSLFFGLKLLRTW 601
            MAS+ G R TGTDGSD++HRE+VA+ Y +S  LK  ++ +   H +VW ++  + +          L       + SP  WE+ + L S+ P++F +++L KN +  L +S+    +F   PI     Y  +E++   Q    +      IFG   V + Y+     +Q+HG+ +++  KLL  W
Sbjct:    1 MASRAGPRATGTDGSDYQHRERVASHYQMSVALKSEIKKLNIAHAVVWFLVAAQVLVS-------QLNLVSHKVVASPYQWEYTYLL-SIIPTVFSFMALPKNNISYLVISMISGGLFCIGPI----LYGGMEMFPVAQQLYRHGKAYRFIFGFSAVSIMYLVLIISVQVHGWQIYYSKKLLDAW 173
[Close]
BLAST of jagunal vs. Ensembl Zebrafish
Match: jagn1b (jagunal homolog 1b [Source:NCBI gene;Acc:445190])

HSP 1 Score: 102.834 bits (255), Expect = 6.208e-27
Identity = 56/185 (30.27%), Postives = 95/185 (51.35%), Query Frame = 2 
Query:   59 MASKTGARPTGTDGSDFRHREKVANQYNISPFLKKRLRFVYSCHTIVWLIILLKFIPEIFRNLGISLEYFKSVNLPSPDTWEFVWFLGSLTPSIFGYLSLSKNRVFLLRVSLFGTMIFGFIPISVGVCYKALELYDFYQTKVSNSN----IFGLPLVVVWYIFFCGCIQIHGFSLFFGLKLLRTW 601
            MAS+ G R TGTDGSD++HRE+VA+ Y +S  LK  ++ +   H +VW ++  + +          L       + SP  WE+ + L S+ P++F +++L KN +  L +S+    +F   PI     Y  +E++   Q    +      IFG   V + Y+     +Q+HG+ +++  KLL  W
Sbjct:    1 MASRAGPRATGTDGSDYQHRERVASHYQMSVALKSEIKKLNIAHAVVWFLVAAQVLVS-------QLNLVSHKVVASPYQWEYTYLL-SIIPTVFSFMALPKNNISYLVISMISGGLFCIGPI----LYGGMEMFPVAQQLYRHGKAYRFIFGFSAVSIMYLVLIISVQVHGWQIYYSKKLLDAW 173
[Close]
BLAST of jagunal vs. Ensembl Zebrafish
Match: jagn1a (jagunal homolog 1a [Source:NCBI gene;Acc:449830])

HSP 1 Score: 97.8265 bits (242), Expect = 5.160e-25
Identity = 61/195 (31.28%), Postives = 97/195 (49.74%), Query Frame = 2 
Query:   59 MASKTGARPTGTDGSDFRHREKVANQYNISPFLKKRLRFVYSCHTIVWLIILLKFIPEIFRNLGISLEYFKSVNLPS-PDTWEFVWFLGSLTPSIFGYLSLSKNRVFLLRVSLFGTMIFGFIPISVGVCYKALELYDFYQTKVSNSN----IFGLPLVVVWYIFFCGCIQIHGFSLFFGLKLLRTW-TGQLHKKN 625
            MAS+ G R  GTDG DF+HREKVA+ Y +S   K  ++ +   H ++W+++  +        + +S     S +L + P  WE+ + L SL PS  G L++ KN +  L +S+    +F   P+  G    A+E++   Q    +      IFG   V V Y+     IQ+H + +++  KLL  W    L KK 
Sbjct:    1 MASRAGPRAAGTDGGDFKHREKVASHYQMSASSKSEIKKLTVVHFLIWILVAAQ--------VAVSHLNLVSHDLVAMPYQWEYPYLL-SLVPSFIGALAMPKNNISYLVISMISAGLFSVAPLIFG----AMEMFPLAQQLYRHGKAYRFIFGFSAVSVMYLLMVIAIQVHAWQIYYSKKLLDAWFNSTLEKKK 182
[Close]
BLAST of jagunal vs. Ensembl Zebrafish
Match: jagn1a (jagunal homolog 1a [Source:NCBI gene;Acc:449830])

HSP 1 Score: 97.8265 bits (242), Expect = 5.160e-25
Identity = 61/195 (31.28%), Postives = 97/195 (49.74%), Query Frame = 2 
Query:   59 MASKTGARPTGTDGSDFRHREKVANQYNISPFLKKRLRFVYSCHTIVWLIILLKFIPEIFRNLGISLEYFKSVNLPS-PDTWEFVWFLGSLTPSIFGYLSLSKNRVFLLRVSLFGTMIFGFIPISVGVCYKALELYDFYQTKVSNSN----IFGLPLVVVWYIFFCGCIQIHGFSLFFGLKLLRTW-TGQLHKKN 625
            MAS+ G R  GTDG DF+HREKVA+ Y +S   K  ++ +   H ++W+++  +        + +S     S +L + P  WE+ + L SL PS  G L++ KN +  L +S+    +F   P+  G    A+E++   Q    +      IFG   V V Y+     IQ+H + +++  KLL  W    L KK 
Sbjct:    1 MASRAGPRAAGTDGGDFKHREKVASHYQMSASSKSEIKKLTVVHFLIWILVAAQ--------VAVSHLNLVSHDLVAMPYQWEYPYLL-SLVPSFIGALAMPKNNISYLVISMISAGLFSVAPLIFG----AMEMFPLAQQLYRHGKAYRFIFGFSAVSVMYLLMVIAIQVHAWQIYYSKKLLDAWFNSTLEKKK 182
[Close]
BLAST of jagunal vs. Ensembl Xenopus
Match: jagn1 (jagunal homolog 1 [Source:NCBI gene;Acc:431675])

HSP 1 Score: 109.768 bits (273), Expect = 2.429e-29
Identity = 61/193 (31.61%), Postives = 98/193 (50.78%), Query Frame = 2 
Query:   59 MASKTGARPTGTDGSDFRHREKVANQYNISPFLKKRLRFVYSCHTIVWLIILLKFIPEIFRNLGISLEYFKSVNLPSPDTWEFVWFLGSLTPSIFGYLSLSKNRVFLLRVSLFGTMIFGFIPISVGVCYKALELYDFYQTKVSNSN----IFGLPLVVVWYIFFCGCIQIHGFSLFFGLKLLRTWTGQLHKKN 625
            MAS+ G R TGTDGSDF+HRE+VA+ Y +S  LK  ++ +   H ++WL+I  +      + +   L       +  P  WE+ + L SL PS+FG +S  +N +  L +S+  T +F   P+     Y  LE++   Q    +      IFG   + V Y+     +Q+HG+ +++  KLL  W     +K 
Sbjct:    1 MASRAGPRATGTDGSDFQHRERVASHYQMSASLKNEIKKLIYAHLVIWLLIAAQMCVSHLKLVSKDL-------VAMPYQWEYPYLL-SLVPSLFGLVSFPRNNISYLVISMISTGLFSIAPL----IYGTLEMFPMAQQLYRHGKAYRFIFGFSAISVMYLLMVVAVQVHGWQIYYSKKLLDAWFTNTQEKK 181
[Close]
BLAST of jagunal vs. Ensembl Mouse
Match: Jagn1 (jagunal homolog 1 [Source:MGI Symbol;Acc:MGI:1915017])

HSP 1 Score: 100.138 bits (248), Expect = 8.067e-26
Identity = 58/193 (30.05%), Postives = 98/193 (50.78%), Query Frame = 2 
Query:   59 MASKTGARPTGTDGSDFRHREKVANQYNISPFLKKRLRFVYSCHTIVWLIILLKFIPEIFRNLGISLEYFKSVNLPSPDTWEFVWFLGSLTPSIFGYLSLSKNRVFLLRVSLFGTMIFGFIPISVGVCYKALELY----DFYQTKVSNSNIFGLPLVVVWYIFFCGCIQIHGFSLFFGLKLLRTWTGQLHKKN 625
            MAS+ G R  GTDGSDF+HRE+VA  Y +S  LK  ++ +   H ++WL+++ K       ++G  L       +  P  WE+ + L S+ PS+ G LS  +N +  L +S+    +F   P+     Y ++E++      Y+   +   +FG   V V Y+     +Q+H + L++  KLL +W     +K 
Sbjct:    1 MASRAGPRAAGTDGSDFQHRERVAMHYQMSVTLKYEIKKLIYVHLVIWLLLVAKM------SVG-HLRLLSHDQVAMPYQWEYPYLL-SIVPSVLGLLSFPRNNISYLVLSMISMGLFSIAPL----IYGSMEMFPAAQQLYRHGKAYRFLFGFSAVSVMYLVLVLAVQVHAWQLYYSKKLLDSWFTSTQEKK 181
[Close]
BLAST of jagunal vs. Ensembl Mouse
Match: Jagn1 (jagunal homolog 1 [Source:MGI Symbol;Acc:MGI:1915017])

HSP 1 Score: 45.0542 bits (105), Expect = 2.124e-6
Identity = 18/29 (62.07%), Postives = 22/29 (75.86%), Query Frame = 2 
Query:   59 MASKTGARPTGTDGSDFRHREKVANQYNI 145
            MAS+ G R  GTDGSDF+HRE+VA  Y +
Sbjct:    1 MASRAGPRAAGTDGSDFQHRERVAMHYQM 29
[Close]
BLAST of jagunal vs. UniProt/SwissProt
Match: sp|Q9XUU9|JAGN_CAEEL (Protein jagunal homolog OS=Caenorhabditis elegans OX=6239 GN=K05C4.2 PE=3 SV=1)

HSP 1 Score: 110.538 bits (275), Expect = 8.014e-29
Identity = 60/184 (32.61%), Postives = 99/184 (53.80%), Query Frame = 2 
Query:   65 SKTGARPTGTDGSDFRHREKVANQYNISPFLKKRLRFVYSCHTIVWLIILLKFIPEIFR-NLGISLEYFKSVNLPSPDTWEFVWFLGSLTPSIFGYLSLSKNRVFLLRVSLFGTMIFGFIPISVGVCYKALELYDFYQT-KVSNSNIFG--LPLVVVWYIFFCGCIQIHGFSLFFGLKLLRTWT 604
            S  G R  GTDG+DF++R++VA  Y  S   K  L++ +  H ++ + + LK   E+ R N G    +F  +++PS   WE+VW   S  P +    S  +N++ +L  + +   + G  P  +G+  +  EL ++ Q  + SN+  F    P+V++WYIFF   +QIHGFS++F   L   W 
Sbjct:    2 SSRGVRAAGTDGTDFQNRQRVAQHYQESAQYKSILKWFFVPHFLILVFMWLKVGSELLRTNFGWKNAFFDRLDMPSAYPWEYVWCF-SFIPIVLAIYSFQRNKLKILHYAYYAEFVVGIFPCMIGLGGQLPELMEYAQDMEGSNTPTFKGIFPMVIIWYIFFAVALQIHGFSMYFMHHLAAAWA 184
[Close]
BLAST of jagunal vs. UniProt/SwissProt
Match: sp|Q6NVQ1|JAGN1_XENTR (Protein jagunal homolog 1 OS=Xenopus tropicalis OX=8364 GN=jagn1 PE=2 SV=1)

HSP 1 Score: 109.768 bits (273), Expect = 1.287e-28
Identity = 61/193 (31.61%), Postives = 98/193 (50.78%), Query Frame = 2 
Query:   59 MASKTGARPTGTDGSDFRHREKVANQYNISPFLKKRLRFVYSCHTIVWLIILLKFIPEIFRNLGISLEYFKSVNLPSPDTWEFVWFLGSLTPSIFGYLSLSKNRVFLLRVSLFGTMIFGFIPISVGVCYKALELYDFYQTKVSNSN----IFGLPLVVVWYIFFCGCIQIHGFSLFFGLKLLRTWTGQLHKKN 625
            MAS+ G R TGTDGSDF+HRE+VA+ Y +S  LK  ++ +   H ++WL+I  +      + +   L       +  P  WE+ + L SL PS+FG +S  +N +  L +S+  T +F   P+     Y  LE++   Q    +      IFG   + V Y+     +Q+HG+ +++  KLL  W     +K 
Sbjct:    1 MASRAGPRATGTDGSDFQHRERVASHYQMSASLKNEIKKLIYAHLVIWLLIAAQMCVSHLKLVSKDL-------VAMPYQWEYPYLL-SLVPSLFGLVSFPRNNISYLVISMISTGLFSIAPL----IYGTLEMFPMAQQLYRHGKAYRFIFGFSAISVMYLLMVVAVQVHGWQIYYSKKLLDAWFTNTQEKK 181
[Close]
BLAST of jagunal vs. UniProt/SwissProt
Match: sp|P0C655|JAGN_CAEBR (Protein jagunal homolog OS=Caenorhabditis briggsae OX=6238 GN=CBG19742 PE=3 SV=1)

HSP 1 Score: 107.071 bits (266), Expect = 1.642e-27
Identity = 59/184 (32.07%), Postives = 99/184 (53.80%), Query Frame = 2 
Query:   65 SKTGARPTGTDGSDFRHREKVANQYNISPFLKKRLRFVYSCHTIVWLIILLKFIPEIFR-NLGISLEYFKSVNLPSPDTWEFVWFLGSLTPSIFGYLSLSKNRVFLLRVSLFGTMIFGFIPISVGVCYKALELYDFYQT-KVSNSNIFG--LPLVVVWYIFFCGCIQIHGFSLFFGLKLLRTWT 604
            S  G R  GTDG+DF++R+++A  Y  S   K  L++ +  H ++ + + LK   E  R N G    +F+ +++P+   WE+VW L S  P +    S  +N++ +L  + +   I G  P  +G+  +  EL ++    + SN+  F    P+V++WYIFF   +QIHGFS++F   L   W 
Sbjct:    2 SSRGVRAAGTDGNDFQNRQRIAQHYQESAQYKSVLKWFFVPHFLILVFMWLKVGSEFLRYNFGWKNAFFERLDMPAAYPWEYVWCL-SFIPIVLALSSFQRNKLKVLHYAYYAEFICGIFPCMIGLGGQLPELLEYANDMEGSNTPTFKGIFPMVIIWYIFFAVALQIHGFSMYFMHHLAAAWA 184
[Close]
BLAST of jagunal vs. UniProt/SwissProt
Match: sp|Q5M7C7|JAGN1_XENLA (Protein jagunal homolog 1 OS=Xenopus laevis OX=8355 GN=jagn1 PE=2 SV=1)

HSP 1 Score: 106.686 bits (265), Expect = 1.760e-27
Identity = 61/193 (31.61%), Postives = 97/193 (50.26%), Query Frame = 2 
Query:   59 MASKTGARPTGTDGSDFRHREKVANQYNISPFLKKRLRFVYSCHTIVWLIILLKFIPEIFRNLGISLEYFKSVNLPSPDTWEFVWFLGSLTPSIFGYLSLSKNRVFLLRVSLFGTMIFGFIPISVGVCYKALELYDFYQTKVSNSN----IFGLPLVVVWYIFFCGCIQIHGFSLFFGLKLLRTWTGQLHKKN 625
            MAS+ G R TG+DGSDF+HREKVA  Y +S  LK  ++ +   H I+W++I  +      + +   L       +  P  WE+ + L SL PS+FG  S  +N +  L +S+  T +F   P+     Y  LE++   Q    +      IFG   + V Y+     +Q+HG+ +++  KLL +W     +K 
Sbjct:    1 MASRAGPRATGSDGSDFQHREKVAGHYKMSASLKNEIKKLIYAHLIIWMLIAAQMCVSHLKLVSKDL-------VAMPYQWEYPYLL-SLVPSLFGLFSFPRNNISYLVISMISTGLFSIGPL----IYGTLEMFPMAQQLYRHGKAYRFIFGFSAISVMYLVMVVAVQVHGWQIYYSKKLLDSWFTNTQEKK 181
[Close]
BLAST of jagunal vs. UniProt/SwissProt
Match: sp|Q297K8|JAGN_DROPS (Protein jagunal OS=Drosophila pseudoobscura pseudoobscura OX=46245 GN=jagn PE=3 SV=1)

HSP 1 Score: 103.605 bits (257), Expect = 4.123e-26
Identity = 58/196 (29.59%), Postives = 100/196 (51.02%), Query Frame = 2 
Query:   59 MASKTGARPTGTDGSDFRHREKVANQYNISPFLKKRLRFVYSCHTIVWLIILLKFIPEIFRNLGISLEYFKSVNLPSPDTWEFVWFLGSLTPSIFGYLSLSKNRVFLLRVSLFGTMIFGFIPISVGVCYKALELYDFY----QTKVSNSNIF---GLPLVVVWYIFFCGCIQIHGFSLFFGLKLLRTWTGQLHKKN 625
            MA++ G    GTDG+DF  R++VA  Y IS   K RL++    H +++ ++L K   +I   L I +   + + +PSP  WE+VW  GSL  S  G  +   N+V  ++  +   ++F  +P+     Y   ++++F       ++  ++IF   G P  V WY F     Q+HGF+L+F   L++ W  +   + 
Sbjct:    1 MATRGGPMVAGTDGNDFEFRQRVAGTYQISLLNKSRLKYCIFFHALLFFVMLAKLTSDILDRLDIFVLEIEELEVPSPLWWEYVW-AGSLLTSFLGLSAARGNKVREMQKYMIAILVFAILPLLYCFAYYFSDVWEFATMDKSVELDETDIFIWRGYPYGVFWYAFCFVGFQVHGFTLYFAYNLVKVWKARTATRK 195
[Close]
BLAST of jagunal vs. TrEMBL
Match: A0A023ZT88 (Jagunal (Fragment) OS=Schmidtea mediterranea OX=79327 PE=2 SV=1)

HSP 1 Score: 378.637 bits (971), Expect = 7.030e-132
Identity = 186/186 (100.00%), Postives = 186/186 (100.00%), Query Frame = 2 
Query:   59 MASKTGARPTGTDGSDFRHREKVANQYNISPFLKKRLRFVYSCHTIVWLIILLKFIPEIFRNLGISLEYFKSVNLPSPDTWEFVWFLGSLTPSIFGYLSLSKNRVFLLRVSLFGTMIFGFIPISVGVCYKALELYDFYQTKVSNSNIFGLPLVVVWYIFFCGCIQIHGFSLFFGLKLLRTWTGQLH 616
            MASKTGARPTGTDGSDFRHREKVANQYNISPFLKKRLRFVYSCHTIVWLIILLKFIPEIFRNLGISLEYFKSVNLPSPDTWEFVWFLGSLTPSIFGYLSLSKNRVFLLRVSLFGTMIFGFIPISVGVCYKALELYDFYQTKVSNSNIFGLPLVVVWYIFFCGCIQIHGFSLFFGLKLLRTWTGQLH
Sbjct:    1 MASKTGARPTGTDGSDFRHREKVANQYNISPFLKKRLRFVYSCHTIVWLIILLKFIPEIFRNLGISLEYFKSVNLPSPDTWEFVWFLGSLTPSIFGYLSLSKNRVFLLRVSLFGTMIFGFIPISVGVCYKALELYDFYQTKVSNSNIFGLPLVVVWYIFFCGCIQIHGFSLFFGLKLLRTWTGQLH 186
[Close]
BLAST of jagunal vs. TrEMBL
Match: A0A5K3FLT1 (Uncharacterized protein OS=Mesocestoides corti OX=53468 PE=4 SV=1)

HSP 1 Score: 190.274 bits (482), Expect = 1.468e-57
Identity = 92/191 (48.17%), Postives = 128/191 (67.02%), Query Frame = 2 
Query:   59 MASKTGARPTGTDGSDFRHREKVANQYNISPFLKKRLRFVYSCHTIVWLIILLKFIPEIFRNLG-ISLEYFKSVNLPSPDTWEFVWFLGSLTPSIFGYLSLSKNRVFLLRVSLFGTMIFGFIPISVGVCYKALELYDFYQTKVSNSNIFGLPLVVVWYIFFCGCIQIHGFSLFFGLKLLRTWTGQLHKKNL 628
            MAS+ GARP G+DGSDF+HRE+V   Y+ S   KKRLR  +  H  +W ++ +K +P+I    G +S  + +   LP  D WE+ W  GS+ P +FGYLS  KN+V+L+R+SL GT++FGF+PI +G   +A EL D+Y TK S  N+F  P VV+ YIFF  CIQIH FSL+F  KL+  W+ +L KK++
Sbjct:    1 MASRCGARPIGSDGSDFQHRERVVEPYSQSSLFKKRLRTTFFLHIALWFLVAMKLLPDILFKFGLVSRLFMRKYPLPPNDLWEYAWAFGSVLPVLFGYLSFGKNKVYLIRLSLLGTIVFGFVPIVMGCFLRAYELMDYYYTKQSRHNLFNFPFVVLIYIFFSICIQIHSFSLYFSWKLMTIWS-RLSKKHV 190
[Close]
BLAST of jagunal vs. TrEMBL
Match: A0A0X3P821 (Protein jagunal homolog 1 OS=Schistocephalus solidus OX=70667 GN=JAGN1 PE=4 SV=1)

HSP 1 Score: 189.889 bits (481), Expect = 2.344e-57
Identity = 93/190 (48.95%), Postives = 128/190 (67.37%), Query Frame = 2 
Query:   59 MASKTGARPTGTDGSDFRHREKVANQYNISPFLKKRLRFVYSCHTIVWLIILLKFIPEIFRNLG-ISLEYFKSVNLPSPDTWEFVWFLGSLTPSIFGYLSLSKNRVFLLRVSLFGTMIFGFIPISVGVCYKALELYDFYQTKVSNSNIFGLPLVVVWYIFFCGCIQIHGFSLFFGLKLLRTWTGQLHKKN 625
            M+S+ G RP GTDG+DF+HRE+VA QYN SP  K+R+R V      VWL+I+ K +PE+    G +S  + +  +LP  D WE+ W  GS+ P IF YLSL KN+V L+R+SL G + FG +PI+VG   K+ EL +FY T++S  N FG P +V+ YIFF  C+Q+H F+LFFG KLL  W+ ++  KN
Sbjct:    1 MSSRYGPRPVGTDGTDFKHRERVAQQYNQSPLFKRRIRTVLYLQVSVWLLIVAKLLPELCIRFGFVSKNFMRKWSLPPADLWEYAWAAGSIFPVIFSYLSLPKNKVSLMRISLLGHVTFGIVPIAVGCFQKSFELINFYYTRLSTYNFFGFPFIVLVYIFFSVCVQLHFFTLFFGYKLLGMWS-RVSTKN 189
[Close]
BLAST of jagunal vs. TrEMBL
Match: A0A0R3SLR1 (Uncharacterized protein OS=Hymenolepis diminuta OX=6216 GN=HDID_LOCUS5874 PE=4 SV=1)

HSP 1 Score: 188.734 bits (478), Expect = 6.815e-57
Identity = 87/190 (45.79%), Postives = 124/190 (65.26%), Query Frame = 2 
Query:   59 MASKTGARPTGTDGSDFRHREKVANQYNISPFLKKRLRFVYSCHTIVWLIILLKFIPEIFRNLG-ISLEYFKSVNLPSPDTWEFVWFLGSLTPSIFGYLSLSKNRVFLLRVSLFGTMIFGFIPISVGVCYKALELYDFYQTKVSNSNIFGLPLVVVWYIFFCGCIQIHGFSLFFGLKLLRTWTGQLHKKN 625
            MAS+ G RP G+DGSDF+HRE+V   YN SP  K+RLR  ++ H  +WL++  K +PE+    G +S  + +   LP  + WE+ W  GS+ P +FG+ + SKNRV+L+R+SL GT++FGF+P+ +G   +A EL DFY T+ S  + F  P VV+ YIFF    QIH F L+F  KL+  W+ +L KKN
Sbjct:    1 MASRFGPRPAGSDGSDFQHRERVVEPYNQSPLFKRRLRTTFTLHITIWLLVAAKVLPEVLFRFGFVSRAFIRRYGLPPNELWEYAWLFGSILPVVFGHFAFSKNRVYLIRLSLIGTIVFGFVPVIMGCFLRAFELMDFYYTRNSRHDFFNFPFVVILYIFFSIAFQIHCFELYFSYKLMTMWS-RLSKKN 189
[Close]
BLAST of jagunal vs. TrEMBL
Match: A0A0R3WK47 (Uncharacterized protein OS=Hydatigena taeniaeformis OX=6205 GN=TTAC_LOCUS1078 PE=4 SV=1)

HSP 1 Score: 187.963 bits (476), Expect = 1.509e-56
Identity = 90/189 (47.62%), Postives = 129/189 (68.25%), Query Frame = 2 
Query:   59 MASKTGARPTGTDGSDFRHREKVANQYNISPFLKKRLRFVYSCHTIVWLIILLKFIPEI-FRNLGISLEYFKSVNLPSPDTWEFVWFLGSLTPSIFGYLSLSKNRVFLLRVSLFGTMIFGFIPISVGVCYKALELYDFYQTKVSNSNIFGLPLVVVWYIFFCGCIQIHGFSLFFGLKLLRTWTGQLHKK 622
            MAS+ GARP G+DGSDF+HRE++   YN S   KKRLR   + H  +W++++LK +PEI FR   +S  + +  ++P  + WE+ W  GS+ P  FGYLS +KN+V+L+R+SL GT++FGF+PI +G   +A EL D+Y TK S  + F  P VV+ Y+FF  CIQIH F+L+F  KL+  W+ +L KK
Sbjct:    1 MASRYGARPVGSDGSDFQHRERIVEPYNQSSLFKKRLRTALTLHIALWVLVVLKILPEILFRFRLVSRAFMRKHSVPLNELWEYAWCFGSIIPVFFGYLSFTKNKVYLIRLSLIGTIVFGFVPIIMGCFLRASELMDYYYTKNSRHDFFNFPFVVILYVFFSVCIQIHCFTLYFSWKLMTIWS-RLSKK 188
[Close]
BLAST of jagunal vs. Ensembl Cavefish
Match: jagn1b (protein jagunal homolog 1-B [Source:NCBI gene;Acc:103039031])

HSP 1 Score: 102.449 bits (254), Expect = 8.226e-27
Identity = 60/195 (30.77%), Postives = 98/195 (50.26%), Query Frame = 2 
Query:   59 MASKTGARPTGTDGSDFRHREKVANQYNISPFLKKRLRFVYSCHTIVWLIILLKFIPEIFRNLGISLEYFKSVNLPSPDTWEFVWFLGSLTPSIFGYLSLSKNRVFLLRVSLFGTMIFGFIPISVGVCYKALELYDFYQTKVSNSN----IFGLPLVVVWYIFFCGCIQIHGFSLFFGLKLLRTW--TGQLHKKN 625
            MAS+ G R TGTDGSDF+HRE+VA+ Y +S  LK  ++ +   H ++W ++  + +          L       + SP  WE+ + L S+ P+   +++L +N +  L +S+    +F   PI     Y  +E++   Q    +      IFG   V V Y+     +Q+HG+ +++  KLL TW  T Q  KK 
Sbjct:    1 MASRAGPRATGTDGSDFQHRERVASHYQMSVALKSEIKKLNLVHAVLWALVAAQVLVS-------QLNLVSHRVVASPYQWEYPYLL-SIIPTAVSFMALPRNNISYLVISMISAGLFCVAPI----IYGGMEMFPVAQQLYRHGKAYRFIFGFSAVSVLYLLMVIAVQVHGWQIYYSKKLLDTWFTTTQDKKKK 183
[Close]
BLAST of jagunal vs. Ensembl Cavefish
Match: jagn1a (protein jagunal homolog 1-A [Source:NCBI gene;Acc:103032247])

HSP 1 Score: 85.1149 bits (209), Expect = 3.558e-20
Identity = 55/193 (28.50%), Postives = 92/193 (47.67%), Query Frame = 2 
Query:   59 MASKTGARPTGTDGSDFRHREKVANQYNISPFLKKRLRFVYSCHTIVWLIILLKFIPEIFRNLGISLEYFKSVNLPSPDTWEFVWFLGSLTPSIFGYLSLSKNRVFLLRVSLFGTMIFGFIPISVGVCYKALELYDFYQTKVSNSN----IFGLPLVVVWYIFFCGCIQIHGFSLFFGLKLLRTWTGQLHKKN 625
            M S+ G R  GTDGSDF+HREKVA+ Y +S  LK  ++ +   H ++W ++  + +    + L   +       +  P  WE+ + L  L   I G L++ KN +  L +S+    +F   P+  G    A+E++   Q    +      IFG   V V Y+     +Q+H + +++  KLL  W     +K 
Sbjct:    1 MTSRAGPRAAGTDGSDFKHREKVASHYQMSASLKSEIKKLTVVHVLIWALVAAQVVVAHLKLLSHDV-------VAMPYQWEYPYLLSLLPSLI-GALAMPKNNISYLVISMISAGLFSVAPLIFG----AMEMFPVAQQLYRHGKAYRFIFGFSAVSVMYLLMIVAVQVHAWQIYYSKKLLDAWFNSTQEKK 181
[Close]
BLAST of jagunal vs. Ensembl Sea Lamprey
Match: jagn1b (jagunal homolog 1b [Source:NCBI gene;Acc:445190])

HSP 1 Score: 45.0542 bits (105), Expect = 2.161e-6
Identity = 38/157 (24.20%), Postives = 73/157 (46.50%), Query Frame = 2 
Query:  146 SPFLKKRLRFVYSCHTIVWLIILLKFIPEIFRNLGISLEYFKSVNLPSPDTWEFVWFLGSLTPSIFGYLSLSKNRVFLLRVSLFGTMIFGFIPI---SVGVCYKALELYDFYQTKVSNSNIFGLPLVVVWYIFFCGCIQIHGFSLFFGLKLLRTWTG 607
            S  L+  +R +   H  +W ++LL+ I    R +  SL       +  P  WE+ + L S+ P++    ++ +   + + +++  T +    P+   SV +   A +LY   Q KV   +I G   V V Y      +Q+H + L++  +LL+ W+ 
Sbjct:    1 SSSLESEVRMLVYVHVALWALVLLQVIVSSLRLVPSSL-------VARPYLWEYPYLL-SVAPALLTIGAMRRRSTYHMVLAMAMTSLVSLGPLVYGSVEMFPMARQLYT--QGKVYR-HILGFSAVSVLYFAMVIAVQVHAWQLYYCKQLLQVWSS 146
[Close]
BLAST of jagunal vs. Ensembl Nematostella
Match: EDO32175 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SVU8])

HSP 1 Score: 84.7297 bits (208), Expect = 1.704e-20
Identity = 55/191 (28.80%), Postives = 93/191 (48.69%), Query Frame = 2 
Query:   59 MASKTGARPTGTDGSDFRHREKVANQYNISPFLKKRLRFVYSCHTIVWLIILLKFIPEIFRNLGISLEYFKSVNLPSPDTWEFVWFLGSLTPSIFGYLSLSKNRVFLLRVSLFGTMIFGFIPISVGVCYKALE-LYDFYQTKVSNSNIFG-LPLVVVWYIFFCGCIQIHGFSLFFGLKLLRTWTGQLHKKN 625
            MAS+ G R +GTDGSDF HRE+VA+ Y  S   K +++F    H    + ++      I R + I           +PD W  +W + S+ P+I G   L KN+  ++ V   GTM+ G  P+  G  +  ++ + +F +     ++ +  LP+ +    F    IQ H  S+++  KL+  W  +  K +
Sbjct:    1 MASRGGPRASGTDGSDFSHRERVASHYRESVRQKAKMKFCILIHMFFGVCVVGWMGLAISRAVKI-----------APDPWILLWLI-SVFPAIAGLSGLPKNQTKMMHVYSIGTMVTGIAPLMYGATFGIMQVMENFKRGHAPGTDDWRVLPMKMAMVAF---VIQAHAVSIYYSNKLISAWNTKGEKSS 176
[Close]
BLAST of jagunal vs. Ensembl Medaka
Match: JAGN1 (jagunal homolog 1 [Source:NCBI gene;Acc:101162195])

HSP 1 Score: 101.679 bits (252), Expect = 1.564e-26
Identity = 63/195 (32.31%), Postives = 101/195 (51.79%), Query Frame = 2 
Query:   59 MASKTGARPTGTDGSDFRHREKVANQYNISPFLKKRLRFVYSCHTIVWLIILLKFIPEIFRNLGISLEYFKSVNLPSPDTWEFVWFLGSLTPSIFGYLSLSKNRVFLLRVSLFGTMIFGFIPISVGVCYKALELYDFYQTKVSNSN----IFGLPLVVVWYIFFCGCIQIHGFSLFFGLKLLRTW--TGQLHKKN 625
            MAS+ G R  GTDGSDF+HRE+VA+ Y +S  LK  +R +   H ++W+++  + I        +SL   K V   SP  WE+ + L S+ P+ F +L+L +N +  L +S+    +F   P+     Y ++E++   Q    +      IFG   V V Y+     +Q+H + +++  KLL  W  T Q  KK 
Sbjct:    1 MASRAGPRAEGTDGSDFQHRERVASHYQMSVSLKSEIRKLNIVHLLIWVLMAAQVIAS-----QLSLVSHKVV--ASPYQWEYPYLL-SIIPTAFSFLALPRNNISHLVISMISAGLFCVAPL----IYGSMEMFPVAQQLFRHGKAYRFIFGFSAVSVMYLVIVIAVQVHAWQIYYSKKLLDQWFTTTQDKKKK 183
[Close]
BLAST of jagunal vs. Ensembl Medaka
Match: JAGN1 (jagunal homolog 1 [Source:NCBI gene;Acc:101162195])

HSP 1 Score: 101.679 bits (252), Expect = 1.564e-26
Identity = 63/195 (32.31%), Postives = 101/195 (51.79%), Query Frame = 2 
Query:   59 MASKTGARPTGTDGSDFRHREKVANQYNISPFLKKRLRFVYSCHTIVWLIILLKFIPEIFRNLGISLEYFKSVNLPSPDTWEFVWFLGSLTPSIFGYLSLSKNRVFLLRVSLFGTMIFGFIPISVGVCYKALELYDFYQTKVSNSN----IFGLPLVVVWYIFFCGCIQIHGFSLFFGLKLLRTW--TGQLHKKN 625
            MAS+ G R  GTDGSDF+HRE+VA+ Y +S  LK  +R +   H ++W+++  + I        +SL   K V   SP  WE+ + L S+ P+ F +L+L +N +  L +S+    +F   P+     Y ++E++   Q    +      IFG   V V Y+     +Q+H + +++  KLL  W  T Q  KK 
Sbjct:    1 MASRAGPRAEGTDGSDFQHRERVASHYQMSVSLKSEIRKLNIVHLLIWVLMAAQVIAS-----QLSLVSHKVV--ASPYQWEYPYLL-SIIPTAFSFLALPRNNISHLVISMISAGLFCVAPL----IYGSMEMFPVAQQLFRHGKAYRFIFGFSAVSVMYLVIVIAVQVHAWQIYYSKKLLDQWFTTTQDKKKK 183
[Close]
BLAST of jagunal vs. Ensembl Medaka
Match: jagn1a (protein jagunal homolog 1-A [Source:NCBI gene;Acc:101164850])

HSP 1 Score: 68.1662 bits (165), Expect = 8.045e-14
Identity = 55/193 (28.50%), Postives = 89/193 (46.11%), Query Frame = 2 
Query:   59 MASKTGARPTGTDGSDFRHREKVANQYNISPFLKKRLRFVYSCHTIVWLIILLKFIPEIFRNLGISLEYFKSVNLPSPDTWEFVWFLGSLTPSIFGYLSLSKNRVFLLRVSLFGTMIFGFIPISVGVCYKALELYDFYQTKVSNSN----IFGLPLVVVWYIFFCGCIQIHGFSLFFGLKLLRTWTGQLHKKN 625
            MAS+   R  GT+G  F+ +EKVA  Y +S  LK  +R +   H ++WL++  +     FR +           + +P  WE+  +L S  P +   LSL KN +  L +S+    +F   P+     Y  +E++   Q    +      IFG   V V YI     +Q+H + L++  KLL +W     +K 
Sbjct:    1 MASRV--RTAGTNGGGFKPKEKVAPLYQMSASLKSEVRKLNLVHLLIWLLVAAQVTVSHFRLVSHD-------TVSTPYQWEYP-YLLSALPLLCSSLSLPKNNISYLVISMISAGLFSVAPL----IYGGMEMFPVAQQLYRHGKAYRFIFGFSAVTVMYIIMVVAVQVHAWQLYYMKKLLDSWFDATQEKK 179
[Close]
BLAST of jagunal vs. Planmine SMEST
Match: SMESG000059090.1 (SMESG000059090.1)

HSP 1 Score: 386.726 bits (992), Expect = 1.315e-138
Identity = 190/190 (100.00%), Postives = 190/190 (100.00%), Query Frame = 2 
Query:   59 MASKTGARPTGTDGSDFRHREKVANQYNISPFLKKRLRFVYSCHTIVWLIILLKFIPEIFRNLGISLEYFKSVNLPSPDTWEFVWFLGSLTPSIFGYLSLSKNRVFLLRVSLFGTMIFGFIPISVGVCYKALELYDFYQTKVSNSNIFGLPLVVVWYIFFCGCIQIHGFSLFFGLKLLRTWTGQLHKKNL 628
            MASKTGARPTGTDGSDFRHREKVANQYNISPFLKKRLRFVYSCHTIVWLIILLKFIPEIFRNLGISLEYFKSVNLPSPDTWEFVWFLGSLTPSIFGYLSLSKNRVFLLRVSLFGTMIFGFIPISVGVCYKALELYDFYQTKVSNSNIFGLPLVVVWYIFFCGCIQIHGFSLFFGLKLLRTWTGQLHKKNL
Sbjct:    1 MASKTGARPTGTDGSDFRHREKVANQYNISPFLKKRLRFVYSCHTIVWLIILLKFIPEIFRNLGISLEYFKSVNLPSPDTWEFVWFLGSLTPSIFGYLSLSKNRVFLLRVSLFGTMIFGFIPISVGVCYKALELYDFYQTKVSNSNIFGLPLVVVWYIFFCGCIQIHGFSLFFGLKLLRTWTGQLHKKNL 190
[Close]
BLAST of jagunal vs. Planmine SMEST
Match: SMESG000035775.1 (SMESG000035775.1)

HSP 1 Score: 75.8702 bits (185), Expect = 7.094e-17
Identity = 48/190 (25.26%), Postives = 94/190 (49.47%), Query Frame = 2 
Query:   59 MASKTGARPTGTDGSDF-RHREKVANQYNISPFLKKRLRFVYSCHTIVWLIILLKFIPEIFRNLGISLEYFKSVNLPSPDTWEFVWFLGSLTPSIFGYLSLSKNRVFLLRVSLFGTMIFGFIPISVGVCYKALELYDFYQTKVSNSNIFGLPLVVVWYIFFCGCIQIHGFSLFFGLKLLRTWTGQLHKKN 625
            M SK   +     GS+   +R++ + + +I+   K+R+ F+      +W+++L++ I + F  +         + L     WE VW  G++   I   +S+    +  LR S    + F  +PI   +  +  +LY  +  +  +++ +   +V+VWY+FF   +Q+HGF+L+FG  LL  W+    KK+
Sbjct:    1 MTSKFHRKNAAKRGSNSDSNRDQSSGKCSIAT-QKRRISFLNFLQMFLWILLLIRQISQ-FYQIKFENSILSHLLLSEHSPWEIVWLAGTIFVVIITQISIRTRSLTYLRFSDILIVCFNIVPIIYAIVIQFQQLYSLFSDENKSADKY---VVIVWYLFFLISVQVHGFALYFGESLLSQWSTNSQKKH 185
The following BLAST results are available for this feature:
BLAST of jagunal vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 2
Match NameE-valueIdentityDescription
JAGN14.384e-2530.41jagunal homolog 1 [Source:HGNC Symbol;Acc:HGNC:269... [more]
JAGN13.987e-748.98jagunal homolog 1 [Source:HGNC Symbol;Acc:HGNC:269... [more]
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BLAST of jagunal vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 2
Match NameE-valueIdentityDescription
K05C4.26.300e-3032.61pep chromosome:WBcel235:I:14720597:14721979:-1 gen... [more]
K05C4.26.300e-3032.61pep chromosome:WBcel235:I:14720588:14721355:-1 gen... [more]
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BLAST of jagunal vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 2
Match NameE-valueIdentityDescription
jagn1.548e-2528.57gene:FBgn0037374 transcript:FBtr0078624[more]
jagn1.548e-2528.57gene:FBgn0037374 transcript:FBtr0078625[more]
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BLAST of jagunal vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 4
Match NameE-valueIdentityDescription
jagn1b6.208e-2730.27jagunal homolog 1b [Source:NCBI gene;Acc:445190][more]
jagn1b6.208e-2730.27jagunal homolog 1b [Source:NCBI gene;Acc:445190][more]
jagn1a5.160e-2531.28jagunal homolog 1a [Source:NCBI gene;Acc:449830][more]
jagn1a5.160e-2531.28jagunal homolog 1a [Source:NCBI gene;Acc:449830][more]
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BLAST of jagunal vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 1
Match NameE-valueIdentityDescription
jagn12.429e-2931.61jagunal homolog 1 [Source:NCBI gene;Acc:431675][more]
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BLAST of jagunal vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 2
Match NameE-valueIdentityDescription
Jagn18.067e-2630.05jagunal homolog 1 [Source:MGI Symbol;Acc:MGI:19150... [more]
Jagn12.124e-662.07jagunal homolog 1 [Source:MGI Symbol;Acc:MGI:19150... [more]
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BLAST of jagunal vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q9XUU9|JAGN_CAEEL8.014e-2932.61Protein jagunal homolog OS=Caenorhabditis elegans ... [more]
sp|Q6NVQ1|JAGN1_XENTR1.287e-2831.61Protein jagunal homolog 1 OS=Xenopus tropicalis OX... [more]
sp|P0C655|JAGN_CAEBR1.642e-2732.07Protein jagunal homolog OS=Caenorhabditis briggsae... [more]
sp|Q5M7C7|JAGN1_XENLA1.760e-2731.61Protein jagunal homolog 1 OS=Xenopus laevis OX=835... [more]
sp|Q297K8|JAGN_DROPS4.123e-2629.59Protein jagunal OS=Drosophila pseudoobscura pseudo... [more]
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BLAST of jagunal vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A023ZT887.030e-132100.00Jagunal (Fragment) OS=Schmidtea mediterranea OX=79... [more]
A0A5K3FLT11.468e-5748.17Uncharacterized protein OS=Mesocestoides corti OX=... [more]
A0A0X3P8212.344e-5748.95Protein jagunal homolog 1 OS=Schistocephalus solid... [more]
A0A0R3SLR16.815e-5745.79Uncharacterized protein OS=Hymenolepis diminuta OX... [more]
A0A0R3WK471.509e-5647.62Uncharacterized protein OS=Hydatigena taeniaeformi... [more]
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BLAST of jagunal vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 2
Match NameE-valueIdentityDescription
jagn1b8.226e-2730.77protein jagunal homolog 1-B [Source:NCBI gene;Acc:... [more]
jagn1a3.558e-2028.50protein jagunal homolog 1-A [Source:NCBI gene;Acc:... [more]
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BLAST of jagunal vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1
Match NameE-valueIdentityDescription
jagn1b2.161e-624.20jagunal homolog 1b [Source:NCBI gene;Acc:445190][more]
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BLAST of jagunal vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of jagunal vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1
Match NameE-valueIdentityDescription
EDO321751.704e-2028.80Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of jagunal vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 3
Match NameE-valueIdentityDescription
JAGN11.564e-2632.31jagunal homolog 1 [Source:NCBI gene;Acc:101162195][more]
JAGN11.564e-2632.31jagunal homolog 1 [Source:NCBI gene;Acc:101162195][more]
jagn1a8.045e-1428.50protein jagunal homolog 1-A [Source:NCBI gene;Acc:... [more]
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BLAST of jagunal vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 2
Match NameE-valueIdentityDescription
SMESG000059090.11.315e-138100.00SMESG000059090.1[more]
SMESG000035775.17.094e-1725.26SMESG000035775.1[more]
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Cross References
External references for this transcript
DatabaseAccession
SmedGD GBrowseSMED30017352
GenBankAHY82410.1
Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30017352 ID=SMED30017352|Name=jagunal|organism=Schmidtea mediterranea sexual|type=transcript|length=701bp
ATTCTATTTTAACTTGTTTTAACTAGTTGTAAATTTAAATTCAAATTATA
CAATACACATGGCATCAAAAACAGGAGCAAGGCCAACAGGAACAGATGGA
TCTGACTTTCGTCACAGGGAAAAAGTTGCTAACCAATATAATATAAGCCC
GTTTTTGAAAAAGCGATTGAGATTCGTCTATTCATGCCATACTATTGTTT
GGTTGATTATTCTTCTGAAATTTATCCCAGAAATTTTTCGAAATTTAGGA
ATTAGTTTAGAATATTTTAAAAGTGTCAATTTGCCTTCTCCTGATACCTG
GGAATTTGTTTGGTTTTTGGGAAGTTTAACTCCATCAATATTTGGTTATT
TATCCCTGTCGAAGAATAGAGTTTTTTTGTTAAGGGTTTCTCTGTTTGGA
ACAATGATTTTTGGGTTTATTCCTATTTCAGTCGGCGTCTGCTATAAAGC
CCTGGAATTATATGATTTCTATCAAACAAAAGTTTCAAATAGCAATATTT
TTGGATTACCTTTGGTGGTTGTGTGGTATATTTTCTTTTGTGGATGTATT
CAAATTCATGGATTTTCCTTATTCTTTGGACTGAAACTATTGCGTACTTG
GACTGGCCAACTTCACAAAAAGAATTTATAATAACCAATCAAATTCATTT
GTTTTTTTAAATAAACGTATGACATTTATTTTGAATATAAATTGCGAAGC
A
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protein sequence of SMED30017352-orf-1

>SMED30017352-orf-1 ID=SMED30017352-orf-1|Name=SMED30017352-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=191bp
MASKTGARPTGTDGSDFRHREKVANQYNISPFLKKRLRFVYSCHTIVWLI
ILLKFIPEIFRNLGISLEYFKSVNLPSPDTWEFVWFLGSLTPSIFGYLSL
SKNRVFLLRVSLFGTMIFGFIPISVGVCYKALELYDFYQTKVSNSNIFGL
PLVVVWYIFFCGCIQIHGFSLFFGLKLLRTWTGQLHKKNL*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: INTERPRO
TermDefinition
IPR009787Jagunal
Vocabulary: cellular component
TermDefinition
GO:0005789endoplasmic reticulum membrane
GO:0016020membrane
GO:0016021integral component of membrane
Vocabulary: biological process
TermDefinition
GO:0007029endoplasmic reticulum organization
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR009787Protein jagunalPFAMPF07086Jagunalcoord: 1..182
e-value: 3.1E-60
score: 203.5
IPR009787Protein jagunalPANTHERPTHR20955UNCHARACTERIZEDcoord: 1..188
NoneNo IPR availableTMHMMTMhelixcoord: 81..100
NoneNo IPR availableTMHMMTMhelixcoord: 39..61
NoneNo IPR availableTMHMMTMhelixcoord: 153..175
NoneNo IPR availableTMHMMTMhelixcoord: 105..127