X-linked retinitis pigmentosa GTPase regulator-like protein

Query: 3004 IRQISLGKNHALILTESGSLYSAGTNECGQLGIENHVLKQNSFVNKNQCLSIIHPMLINIELNSDECIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHGDIDDQFVSKRLIFDFNNSGSGQEFPIELSMGCFHSVILTNKGFVYCFGNNSYGQLGV-QTLQKSLVPNLVDRLPP-AVIHVDTKYFHTVCCTASNEIFTWGIHPNIWQNSLNHEKSHGEISIPESIYTGDLLSNQKIAQISCGTCHASILTDKQFVYCFGSNVWGQLGLGNRKDNKN 3852
            +++++ G NH++ L E G +Y+ G N  GQLG E          NK + +  +          +D+ I  +A G+ HS A+       +    +F+WG G  GQLG    +D     RLI   N     Q+  +++S G +H + L   G  + +G NS+GQLG+ +       P  V  L    +  V     H+   + S  +F WG++ N  Q  L+ EK        ES     LL  QK+  ISCG  H ++LT    V+ FG+   GQLG  +  D  N
Sbjct:   36 VKEVACGGNHSVFLLEDGEVYTCGLNTKGQLGHEREG-------NKPEQIGAL----------ADQHIIHVACGESHSLAL-------SDRGQLFSWGAGSDGQLGLMTTEDSVAVPRLIQKLN-----QQTILQVSCGNWHCLALAADGQFFTWGKNSHGQLGLGKEFPSQASPQRVRSLEGIPLAQVAAGGAHSFALSLSGAVFGWGMN-NAGQLGLSDEKDR------ESPCHVKLLRTQKVVYISCGEEHTAVLTKSGGVFTFGAGSCGQLGHDSMNDEVN 284          

Query: 3193 SDECIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGH---GDIDDQFVSKRLIFDFNNSGSGQEFPIELSMGCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKSL-VPNLVDRL-PPAVIHVDTKYFHTVCCTASNEIFTWGIHPNIWQNSLNHEKSHGEISI---------PESIYTGDLLSNQKIAQISCGTCHASILTDKQFVYCFGSNVWGQLGLGNRKDNKNLVEVNI--PVPIDFVSSDDGITIAMSKSENSTKLFVWGRCGHSLIQEHIKNPVSDTLKPQLLIE 4038
            SD  +  +A G  HS  ++       ++  V+T G    GQLGH   G+  +Q                 +  I ++ G  HS+ L+++G ++ +G  S GQLG+ T + S+ VP L+ +L    ++ V    +H +   A  + FTWG            + SHG++ +         P+ + +   L    +AQ++ G  H+  L+    V+ +G N  GQLGL + KD ++   V +     + ++S  +  T  ++KS      F  G CG     +   + ++D + P+ ++E
Sbjct:   32 SDRSVKEVACGGNHSVFLL-------EDGEVYTCGLNTKGQLGHEREGNKPEQI-----------GALADQHIIHVACGESHSLALSDRGQLFSWGAGSDGQLGLMTTEDSVAVPRLIQKLNQQTILQVSCGNWHCLALAADGQFFTWG------------KNSHGQLGLGKEFPSQASPQRVRS---LEGIPLAQVAAGGAHSFALSLSGAVFGWGMNNAGQLGLSDEKDRESPCHVKLLRTQKVVYISCGEEHTAVLTKS-GGVFTFGAGSCG-----QLGHDSMNDEVNPRRVLE 290          

Query: 2974 PKSIESGKEI-IRQISLGKNHALILTESGSLYSAGTNECGQLGIENHVLKQNSFVNKNQCLSIIHPMLINIELNSDECIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHGDIDDQFVSKRLIFDFNNSGSGQEFPIELSMGCFHSV-ILTNKGFVYCFGNNSYGQLGV 3498
            P+ + S + I + Q++ G  H+  L+ SG+++  G N  GQLG+ +   +++                 +++L   + +  I+ G+ H+  +       T++  VFT+G G  GQLGH  ++D+ V+ R + +   S   Q     ++ G  H++  + + G +Y FG  + GQLG 
Sbjct:  181 PQRVRSLEGIPLAQVAAGGAHSFALSLSGAVFGWGMNNAGQLGLSDEKDRESP---------------CHVKLLRTQKVVYISCGEEHTAVL-------TKSGGVFTFGAGSCGQLGHDSMNDE-VNPRRVLELMGSEVTQ-----IACGRQHTLAFVPSSGLIYAFGCGARGQLGT 329          

Query: 2971 LPKSIES-GKEIIRQISLGKNHALILTESGSLYSAGTNECGQLGIENHVLKQNSFVNKNQCLSIIHPMLINIELNSDECIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHGDIDDQ--------FVSKRLIFDFNNSGSGQEFPIELSMGCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKSLVPNLV-DRLPPAVIHVDTKYFHTVC-CTASNEIFTWG 3624
            +P+ I+   ++ I Q+S G  H L L   G  ++ G N  GQLG+      Q S   + + L  I              +  +AAG  HS A+ +S +       VF WG    GQLG  D  D+          ++++++              +S G  H+ +LT  G V+ FG  S GQLG  ++   + P  V + +   V  +     HT+    +S  I+ +G
Sbjct:  127 VPRLIQKLNQQTILQVSCGNWHCLALAADGQFFTWGKNSHGQLGLGKEFPSQAS-PQRVRSLEGIP-------------LAQVAAGGAHSFALSLSGA-------VFGWGMNNAGQLGLSDEKDRESPCHVKLLRTQKVVY--------------ISCGEEHTAVLTKSGGVFTFGAGSCGQLGHDSMNDEVNPRRVLELMGSEVTQIACGRQHTLAFVPSSGLIYAFG 320          

Query: 3004 IRQISLGKNHALILTESGSLYSAGTNECGQLGIENHVLKQNSFVNKNQCLSIIHPMLINIELNSDECIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHGDIDDQFVSKRLIFDFNNSGSGQEFPIELSMGCFHSVILTNKGFVYCFGNNSYGQLGV-QTLQKSLVPNLVDRLPP-AVIHVDTKYFHTVCCTASNEIFTWGIHPNIWQNSLNHEKSHGEISIPESIYTGDLLSNQKIAQISCGTCHASILTDKQFVYCFGSNVWGQLGLGNRKDNKN 3852
            +++++ G NH++ L E G +Y+ G N  GQLG E          NK + +  +          +D+ I  +A G+ HS A+       +    +F+WG G  GQLG    +D     RLI   N     Q+  +++S G +H + L   G  + +G NS+GQLG+ +       P  V  L    +  V     H+   + S  +F WG++ N  Q  L+ EK        ES     LL  QK+  ISCG  H ++LT    V+ FG+   GQLG  +  D  N
Sbjct:   36 VKEVACGGNHSVFLLEDGEVYTCGLNTKGQLGHEREG-------NKPEQIGAL----------ADQHIIHVACGESHSLAL-------SDRGQLFSWGAGSDGQLGLMTTEDSVAVPRLIQKLN-----QQTILQVSCGNWHCLALAADGQFFTWGKNSHGQLGLGKEFPSQASPQRVRSLEGIPLAQVAAGGAHSFALSLSGAVFGWGMN-NAGQLGLSDEKDR------ESPCHVKLLRTQKVVYISCGEEHTAVLTKSGGVFTFGAGSCGQLGHDSMNDEVN 284          

Query: 3193 SDECIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGH---GDIDDQFVSKRLIFDFNNSGSGQEFPIELSMGCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKSL-VPNLVDRL-PPAVIHVDTKYFHTVCCTASNEIFTWGIHPNIWQNSLNHEKSHGEISI---------PESIYTGDLLSNQKIAQISCGTCHASILTDKQFVYCFGSNVWGQLGLGNRKDNKNLVEVNI--PVPIDFVSSDDGITIAMSKSENSTKLFVWGRCGHSLIQEHIKNPVSDTLKPQLLIE 4038
            SD  +  +A G  HS  ++       ++  V+T G    GQLGH   G+  +Q                 +  I ++ G  HS+ L+++G ++ +G  S GQLG+ T + S+ VP L+ +L    ++ V    +H +   A  + FTWG            + SHG++ +         P+ + +   L    +AQ++ G  H+  L+    V+ +G N  GQLGL + KD ++   V +     + ++S  +  T  ++KS      F  G CG     +   + ++D + P+ ++E
Sbjct:   32 SDRSVKEVACGGNHSVFLL-------EDGEVYTCGLNTKGQLGHEREGNKPEQI-----------GALADQHIIHVACGESHSLALSDRGQLFSWGAGSDGQLGLMTTEDSVAVPRLIQKLNQQTILQVSCGNWHCLALAADGQFFTWG------------KNSHGQLGLGKEFPSQASPQRVRS---LEGIPLAQVAAGGAHSFALSLSGAVFGWGMNNAGQLGLSDEKDRESPCHVKLLRTQKVVYISCGEEHTAVLTKS-GGVFTFGAGSCG-----QLGHDSMNDEVNPRRVLE 290          

Query: 2974 PKSIESGKEI-IRQISLGKNHALILTESGSLYSAGTNECGQLGIENHVLKQNSFVNKNQCLSIIHPMLINIELNSDECIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHGDIDDQFVSKRLIFDFNNSGSGQEFPIELSMGCFHSV-ILTNKGFVYCFGNNSYGQLGV 3498
            P+ + S + I + Q++ G  H+  L+ SG+++  G N  GQLG+ +   +++                 +++L   + +  I+ G+ H+  +       T++  VFT+G G  GQLGH  ++D+ V+ R + +   S   Q     ++ G  H++  + + G +Y FG  + GQLG 
Sbjct:  181 PQRVRSLEGIPLAQVAAGGAHSFALSLSGAVFGWGMNNAGQLGLSDEKDRESP---------------CHVKLLRTQKVVYISCGEEHTAVL-------TKSGGVFTFGAGSCGQLGHDSMNDE-VNPRRVLELMGSEVTQ-----IACGRQHTLAFVPSSGLIYAFGCGARGQLGT 329          

Query: 2971 LPKSIES-GKEIIRQISLGKNHALILTESGSLYSAGTNECGQLGIENHVLKQNSFVNKNQCLSIIHPMLINIELNSDECIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHGDIDDQ--------FVSKRLIFDFNNSGSGQEFPIELSMGCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKSLVPNLV-DRLPPAVIHVDTKYFHTVC-CTASNEIFTWG 3624
            +P+ I+   ++ I Q+S G  H L L   G  ++ G N  GQLG+      Q S   + + L  I              +  +AAG  HS A+ +S +       VF WG    GQLG  D  D+          ++++++              +S G  H+ +LT  G V+ FG  S GQLG  ++   + P  V + +   V  +     HT+    +S  I+ +G
Sbjct:  127 VPRLIQKLNQQTILQVSCGNWHCLALAADGQFFTWGKNSHGQLGLGKEFPSQAS-PQRVRSLEGIP-------------LAQVAAGGAHSFALSLSGA-------VFGWGMNNAGQLGLSDEKDRESPCHVKLLRTQKVVY--------------ISCGEEHTAVLTKSGGVFTFGAGSCGQLGHDSMNDEVNPRRVLELMGSEVTQIACGRQHTLAFVPSSGLIYAFG 320          

Query: 3004 IRQISLGKNHALILTESGSLYSAGTNECGQLGIENHVLKQNSFVNKNQCLSIIHPMLINIELNSDECIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHGDIDDQFVSKRLIFDFNNSGSGQEFPIELSMGCFHSVILTNKGFVYCFGNNSYGQLGV-QTLQKSLVPNLVDRLPP-AVIHVDTKYFHTVCCTASNEIFTWGIHPNIWQNSLNHEKSHGEISIPESIYTGDLLSNQKIAQISCGTCHASILTDKQFVYCFGSNVWGQLGLGNRKDNKN 3852
            +++++ G NH++ L E G +Y+ G N  GQLG E          NK + +  +          +D+ I  +A G+ HS A+       +    +F+WG G  GQLG    +D     RLI   N     Q+  +++S G +H + L   G  + +G NS+GQLG+ +       P  V  L    +  V     H+   + S  +F WG++ N  Q  L+ EK        ES     LL  QK+  ISCG  H ++LT    V+ FG+   GQLG  +  D  N
Sbjct:   36 VKEVACGGNHSVFLLEDGEVYTCGLNTKGQLGHEREG-------NKPEQIGAL----------ADQHIIHVACGESHSLAL-------SDRGQLFSWGAGSDGQLGLMTTEDSVAVPRLIQKLN-----QQTILQVSCGNWHCLALAADGQFFTWGKNSHGQLGLGKEFPSQASPQRVRSLEGIPLAQVAAGGAHSFALSLSGAVFGWGMN-NAGQLGLSDEKDR------ESPCHVKLLRTQKVVYISCGEEHTAVLTKSGGVFTFGAGSCGQLGHDSMNDEVN 284          

Query: 3193 SDECIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGH---GDIDDQFVSKRLIFDFNNSGSGQEFPIELSMGCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKSL-VPNLVDRL-PPAVIHVDTKYFHTVCCTASNEIFTWGIHPNIWQNSLNHEKSHGEISI---------PESIYTGDLLSNQKIAQISCGTCHASILTDKQFVYCFGSNVWGQLGLGNRKDNKNLVEVNI--PVPIDFVSSDDGITIAMSKSENSTKLFVWGRCGHSLIQEHIKNPVSDTLKPQLLIE 4038
            SD  +  +A G  HS  ++       ++  V+T G    GQLGH   G+  +Q                 +  I ++ G  HS+ L+++G ++ +G  S GQLG+ T + S+ VP L+ +L    ++ V    +H +   A  + FTWG            + SHG++ +         P+ + +   L    +AQ++ G  H+  L+    V+ +G N  GQLGL + KD ++   V +     + ++S  +  T  ++KS      F  G CG     +   + ++D + P+ ++E
Sbjct:   32 SDRSVKEVACGGNHSVFLL-------EDGEVYTCGLNTKGQLGHEREGNKPEQI-----------GALADQHIIHVACGESHSLALSDRGQLFSWGAGSDGQLGLMTTEDSVAVPRLIQKLNQQTILQVSCGNWHCLALAADGQFFTWG------------KNSHGQLGLGKEFPSQASPQRVRS---LEGIPLAQVAAGGAHSFALSLSGAVFGWGMNNAGQLGLSDEKDRESPCHVKLLRTQKVVYISCGEEHTAVLTKS-GGVFTFGAGSCG-----QLGHDSMNDEVNPRRVLE 290          

Query: 2974 PKSIESGKEI-IRQISLGKNHALILTESGSLYSAGTNECGQLGIENHVLKQNSFVNKNQCLSIIHPMLINIELNSDECIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHGDIDDQFVSKRLIFDFNNSGSGQEFPIELSMGCFHSV-ILTNKGFVYCFGNNSYGQLGV 3498
            P+ + S + I + Q++ G  H+  L+ SG+++  G N  GQLG+ +   +++                 +++L   + +  I+ G+ H+  +       T++  VFT+G G  GQLGH  ++D+ V+ R + +   S   Q     ++ G  H++  + + G +Y FG  + GQLG 
Sbjct:  181 PQRVRSLEGIPLAQVAAGGAHSFALSLSGAVFGWGMNNAGQLGLSDEKDRESP---------------CHVKLLRTQKVVYISCGEEHTAVL-------TKSGGVFTFGAGSCGQLGHDSMNDE-VNPRRVLELMGSEVTQ-----IACGRQHTLAFVPSSGLIYAFGCGARGQLGT 329          

Query: 2971 LPKSIES-GKEIIRQISLGKNHALILTESGSLYSAGTNECGQLGIENHVLKQNSFVNKNQCLSIIHPMLINIELNSDECIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHGDIDDQ--------FVSKRLIFDFNNSGSGQEFPIELSMGCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKSLVPNLV-DRLPPAVIHVDTKYFHTVC-CTASNEIFTWG 3624
            +P+ I+   ++ I Q+S G  H L L   G  ++ G N  GQLG+      Q S   + + L  I P+              +AAG  HS A+ +S +       VF WG    GQLG  D  D+          ++++++              +S G  H+ +LT  G V+ FG  S GQLG  ++   + P  V + +   V  +     HT+    +S  I+ +G
Sbjct:  127 VPRLIQKLNQQTILQVSCGNWHCLALAADGQFFTWGKNSHGQLGLGKEFPSQAS-PQRVRSLEGI-PLA------------QVAAGGAHSFALSLSGA-------VFGWGMNNAGQLGLSDEKDRESPCHVKLLRTQKVVY--------------ISCGEEHTAVLTKSGGVFTFGAGSCGQLGHDSMNDEVNPRRVLELMGSEVTQIACGRQHTLAFVPSSGLIYAFG 320          

Query: 2998 EIIRQISL---GKNHALILTESGSLYSAGTNECGQLGIENHVLKQNSFVNKNQCLSIIHPMLINIELNSDECIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHGDIDDQFVSKRLIFDFNNSGSGQEFPIELSMGCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKSLVPNLVDRLPPAVIHVDTKYFHTVCCTA---SNEIFTWGIHPNIWQNSLNHEKSHGEISIPESIYTGDLLSNQKIAQISCGTCHASILTDKQFVYCFGSNVWGQLGLGNRKDNKNLVEVNIPVPIDFVSSDDGITIAMSKSENSTK-------LFVWGRC-GHSLIQEHI 3993
            ++IRQ  +     N  L  T +  ++  GTN CG LG+                 S I P  ++  LN  +    IA   Y SG  +V     T    VFTWG   + QLG+G  +   V   +  + +N     +  IE++ G +HS++LT+ G V+ +G N+ GQ+G  +     +P  V       + V T     +CC A   + E++ WG + N  Q  L +    G    P  +     L   ++ +++CG  H  +LTD+  VY +G+N +GQLG GN+ +       + P P+  V  D  I IA   S +++        +++WG+C G S+I  H+
Sbjct:   48 QLIRQACVFGSAGNEVLYTTVNDEIFVLGTNCCGCLGL-------------GDVQSTIEPRRLD-SLNGKK----IACLSYGSGPHIVLA---TTEGEVFTWGHNAYSQLGNGTTNHGLVPCHISTNLSN-----KQVIEVACGSYHSLVLTSDGEVFAWGYNNSGQVGSGSTVNQPIPRRVTGCLQNKV-VVTIACGQMCCMAVVDTGEVYVWGYNGN-GQLGLGNS---GNQPTPCRVAA---LQGIRVQRVACGYAHTLVLTDEGQVYAWGANSYGQLGTGNKSNQ------SYPTPVT-VEKDRIIEIAACHSTHTSAAKTQGGHVYMWGQCRGQSVILPHL 352          

Query: 2998 EIIRQISL---GKNHALILTESGSLYSAGTNECGQLGIENHVLKQNSFVNKNQCLSIIHPMLINIELNSDECIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHGDIDDQFVSKRLIFDFNNSGSGQEFPIELSMGCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKSLVPNLVDRLPPAVIHVDTKYFHTVCCTA---SNEIFTWGIHPNIWQNSLNHEKSHGEISIPESIYTGDLLSNQKIAQISCGTCHASILTDKQFVYCFGSNVWGQLGLGNRKDNKNLVEVNIPVPIDFVSSDDGITIAMSKSENSTK-------LFVWGRC-GHSLIQEHIKN 3999
            ++IRQ  +     N  L  T +  ++  GTN CG LG+                 S I P  ++  LN  +    IA   Y SG  +V     T    VFTWG   + QLG+G  +   V   +  + +N     +  IE++ G +HS++LT+ G V+ +G N+ GQ+G  +     +P  V       + V T     +CC A   + E++ WG + N  Q  L +    G    P  +     L   ++ +++CG  H  +LTD+  VY +G+N +GQLG GN+ +       + P P+  V  D  I IA   S +++        +++WG+C G S+I  H+ +
Sbjct:   19 QLIRQACVFGSAGNEVLYTTVNDEIFVLGTNCCGCLGL-------------GDVQSTIEPRRLD-SLNGKK----IACLSYGSGPHIVLA---TTEGEVFTWGHNAYSQLGNGTTNHGLVPCHISTNLSN-----KQVIEVACGSYHSLVLTSDGEVFAWGYNNSGQVGSGSTVNQPIPRRVTGCLQNKV-VVTIACGQMCCMAVVDTGEVYVWGYNGN-GQLGLGNS---GNQPTPCRVAA---LQGIRVQRVACGYAHTLVLTDEGQVYAWGANSYGQLGTGNKSNQ------SYPTPVT-VEKDRIIEIAACHSTHTSAAKTQGGHVYMWGQCRGQSVILPHLTH 325          

Query: 2971 LPKSIESGKEIIRQISLGKNHALILTESGSLYSAGTNECGQLGIENHVLKQNSFVNKNQCLSIIHPMLINIELNSD-ECIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHGDIDD--QFVSKR---LIFDFNNSGSGQEFPIELSMGCFHSVILTNKGFVYCFGNNSYGQLGVQT-LQKSLVPNLVDRLPPAVIHVDTKYFHTVCCTASNEIFTWGIHPNIWQ------------------------NSLNHEKSHGEISIPESIYTGDL-------LSNQKIAQISCGTCHASILTDKQFVYCFGSNVWGQLGLGNRKDNKNLVEVNIPVPIDFVSSDDGITIAMSKSENSTKLFVWGR 3963
            LP+ +E      R I+ G  H L+L+ SG L + G N  GQ G+  H  +          ++ +H      +++ D   I  IA G +HS  I    S       ++T+GWGV GQLGHG  ++  Q V  R   LI              +++ G  H+V+LT+ G V   G+ SYGQ+GV   ++K      +   P  V  + T Y+H++C T  N +F WG +P   +                         S N       +++P  I   DL         +  I  ++CG  H++++T +  +Y +G  +  QLG GN+ +     +V  P    +V+   G    ++ +++ + +F WG+
Sbjct:  761 LPRVLEYPGGRPRAIACGAEHILVLSSSGQLSAWGGNRFGQCGV-GHSFR----------IANLH------QVDGDWPAIEKIACGQFHSAFICSDGS-------LWTFGWGVWGQLGHGGRNNSNQLVPTRVNGLICKVT----------QIACGRAHTVVLTDTGRVLVCGSGSYGQMGVDDDIKKVFAFTPLPLGPLRVRDIATHYYHSICITEDNRVFEWGRNPQELKMRMFVMKKIRSAQLKNTEDPSSPSPSTNGSTPRVNLNLPAEIPREDLGLREVKHFLDGNIVSVACGLSHSALITSEGTLYTWGKGLDYQLGHGNKNERMEPHQVFEPNGAKWVNVSLGNNHTIASTDDGS-VFAWGK 1094          

Query: 3196 DECIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHGDIDDQFVSKRLIFDFNNSGSGQEFPIELSMGCFHSVILTNKGFVYCFGNNSYGQLGVQT 3504
            D  I S+A G  HS  I       T    ++TWG G+  QLGHG+ +++    + +F+ N    G ++ + +S+G  H++  T+ G V+ +G N +GQ GV T
Sbjct: 1015 DGNIVSVACGLSHSALI-------TSEGTLYTWGKGLDYQLGHGNKNERMEPHQ-VFEPN----GAKW-VNVSLGNNHTIASTDDGSVFAWGKNDFGQCGVLT 1104          

Query: 2959 RILLLPKSIESGKEIIRQISLGKNHALILTESGSLYSAGTNECGQLGIENHVLKQNSFVNKNQCLSIIHPMLINIELNSDECIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHGDIDDQFV---SKRLIFDFNNSGSGQEFPIELSMGCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKSLVPNLVDRLPPA-VIHVDTKYFHTVCCTASNEIFTWGIHPNIWQNSLNHEKSHGEISIPE-----SIYTGDLLSNQKIAQISCGTCHASILTDKQFVYCFGSNVWGQLGLG---NRKDNKNLVEVNIPVPIDFVSSDDGITIAMSKS 3930
            RI+  P  ++     +  ++ G+ H + LT+ G ++S G+N  GQLG  +    + SF         I+P    +   S   I  I+AG  H+ ++       T +  VF WG   HGQLG   ++ +F    + R + + N+        ++++ G  H + L   G V+ +G  + G    + + +   P  V++L    ++ V     H +  +AS  +FTWG            + + GE+ I +     S+     +    + + +CG  H  +LT     + FGS+  GQ G G    ++ N   V   I   +  +++    TIA+ K 
Sbjct:   30 RIIGAPNDMDG--TAVTSVTCGEQHTVFLTKDGKMWSVGSNMDGQLGRGSRT--EGSFS--------IYP----VSWTSSAKIIQISAGRSHTVSV-------TDDGRVFAWGSNEHGQLG---MESKFTWQGTPRRVQEINDI-------VQVASGSNHCIALDEGGRVFVWGEQADG----RCIHR---PEPVEQLSGVPIVRVLAGARHCLALSASGAVFTWG------------QNNSGELGIDDLRPQTSVQHVHQMDGLGVVEAACGDNHTVLLTHCGRTFSFGSDALGQCGFGKKVEKRTNPTAVSDLIGSHVTRIAAGACHTIAICKG 313          

Query: 3469 GNNSYGQLGVQTLQKSL-VPNLVDRLP-----PAVIHVDTKYFHTVCCTASNEIFTWGIHPNIWQNSLNHEKSHGEISIPESIYTGDLLSNQKIAQISCGTCHASILTDKQFVYCFGSNVWGQLGLGNR----KDNKNLVEVNIPVPIDFVSSDDGITIAMSKSENSTKLFVW-----GRCGH 3972
            G+   GQLGV+  + ++ VP  +   P      AV  V     HTV  T   ++  W +  N+        ++ G  SI    Y     S+ KI QIS G  H   +TD   V+ +GSN  GQLG+ ++       + + E+N     D V    G    ++  E   ++FVW     GRC H
Sbjct:    9 GHTGEGQLGVRLSESTIQVPERIIGAPNDMDGTAVTSVTCGEQHTVFLTKDGKM--WSVGSNMDGQLGRGSRTEGSFSI----YPVSWTSSAKIIQISAGRSHTVSVTDDGRVFAWGSNEHGQLGMESKFTWQGTPRRVQEIN-----DIVQVASGSNHCIALDEGG-RVFVWGEQADGRCIH 179          

Query: 2959 RILLLPKSIESGKEIIRQISLGKNHALILTESGSLYSAGTNECGQLGIENHVLKQNSFVNKNQCLSIIHPMLINIELNSDECIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHGDIDDQFV---SKRLIFDFNNSGSGQEFPIELSMGCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKSLVPNLVDRLPPA-VIHVDTKYFHTVCCTASNEIFTWGIHPNIWQNSLNHEKSHGEISIPE-----SIYTGDLLSNQKIAQISCGTCHASILTDKQFVYCFGSNVWGQLGLG---NRKDNKNLVEVNIPVPIDFVSSDDGITIAMSKS 3930
            RI+  P  ++     +  ++ G+ H + LT+ G ++S G+N  GQLG  +    + SF         I+P    +   S   I  I+AG  H+ ++       T +  VF WG   HGQLG   ++ +F    + R + + N+        ++++ G  H + L   G V+ +G  + G    + + +   P  V++L    ++ V     H +  +AS  +FTWG            + + GE+ I +     S+     +    + + +CG  H  +LT     + FGS+  GQ G G    ++ N   V   I   +  +++    TIA+ K 
Sbjct:   30 RIIGAPNDMDG--TAVTSVTCGEQHTVFLTKDGKMWSVGSNMDGQLGRGSRT--EGSFS--------IYP----VSWTSSAKIIQISAGRSHTVSV-------TDDGRVFAWGSNEHGQLG---MESKFTWQGTPRRVQEINDI-------VQVASGSNHCIALDEGGRVFVWGEQADG----RCIHR---PEPVEQLSGVPIVRVLAGARHCLALSASGAVFTWG------------QNNSGELGIDDLRPQTSVQHVHQMDGLGVVEAACGDNHTVLLTHCGRTFSFGSDALGQCGFGKKVEKRTNPTAVSDLIGSHVTRIAAGACHTIAICKG 313          

Query: 3469 GNNSYGQLGVQTLQKSL-VPNLVDRLP-----PAVIHVDTKYFHTVCCTASNEIFTWGIHPNIWQNSLNHEKSHGEISIPESIYTGDLLSNQKIAQISCGTCHASILTDKQFVYCFGSNVWGQLGLGNR----KDNKNLVEVNIPVPIDFVSSDDGITIAMSKSENSTKLFVW-----GRCGH 3972
            G+   GQLGV+  + ++ VP  +   P      AV  V     HTV  T   ++  W +  N+        ++ G  SI    Y     S+ KI QIS G  H   +TD   V+ +GSN  GQLG+ ++       + + E+N     D V    G    ++  E   ++FVW     GRC H
Sbjct:    9 GHTGEGQLGVRLSESTIQVPERIIGAPNDMDGTAVTSVTCGEQHTVFLTKDGKM--WSVGSNMDGQLGRGSRTEGSFSI----YPVSWTSSAKIIQISAGRSHTVSVTDDGRVFAWGSNEHGQLGMESKFTWQGTPRRVQEIN-----DIVQVASGSNHCIALDEGG-RVFVWGEQADGRCIH 179          

Query: 3406 ELSMGCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKSLVPNLVDRLPPAVIHV--DTKYFHTVCCTASNEIFTWGIHPNIWQNSLNHEKSHGEISIPESIYTGDLLSNQKIAQISCGTCHASILTDKQFVYCFGSNVWGQLGLGNRK-----------DNKNLVEVNIPVPIDFVSSDDGITIAMSKSENSTKLFVWGRCGHSLIQEHIKNPVSDTLKPQLLIEY-QHVVDNHLAWKNCFGIDTVVNGIPKIISKKQLMIIFLN 4155
            ++++   H+++LTN   ++ FG+NS GQLG     K     LV+ L    I       YF  +CC     + T+G   N     L   K   + + P  +   + L  + I  I CG  H   + +      +GSN +GQLGL   +            NK +V          + SDDG  IAM  S    KL +  R G     +  K P     KP +L  + + VVD        F + +  +G+  I+   Q+MI   N
Sbjct:  433 QVALSKTHTMVLTNDNELFGFGDNSCGQLGFGKFSKMENGRLVESLKGRDIQSVGVGNYFSVICCDRGT-LLTFGTAKN-----LGLGKDAKDSAKPMLL---EQLLRENIKDIYCGHDHVVAVLESGECLGWGSNQYGQLGLPTLEHFFAPTKIPMPSNKKIVYGKAGKDATMLLSDDGSLIAMG-SNKHNKLNLTQRVG--FFTKEKKTPNDYVNKPTILQGFPERVVD--------FSVGSYHSGV--ILESGQVMIFGRN 674          

Query: 3406 ELSMGCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKSLVPNLVDRLPPAVIHV--DTKYFHTVCCTASNEIFTWGIHPNIWQNSLNHEKSHGEISIPESIYTGDLLSNQKIAQISCGTCHASILTDKQFVYCFGSNVWGQLGLGNRK-----------DNKNLVEVNIPVPIDFVSSDDGITIAMSKSENSTKLFVWGRCGHSLIQEHIKNPVSDTLKPQLLIEY-QHVVDNHLAWKNCFGIDTVVNGIPKIISKKQLMIIFLN 4155
            ++++   H+++LTN   ++ FG+NS GQLG     K     LV+ L    I       YF  +CC     + T+G   N     L   K   + + P  +   + L  + I  I CG  H   + +      +GSN +GQLGL   +            NK +V          + SDDG  IAM  S    KL +  R G     +  K P     KP +L  + + VVD        F + +  +G+  I+   Q+MI   N
Sbjct:  471 QVALSKTHTMVLTNDNELFGFGDNSCGQLGFGKFSKMENGRLVESLKGRDIQSVGVGNYFSVICCDRGT-LLTFGTAKN-----LGLGKDAKDSAKPMLL---EQLLRENIKDIYCGHDHVVAVLESGECLGWGSNQYGQLGLPTLEHFFAPTKIPMPSNKKIVYGKAGKDATMLLSDDGSLIAMG-SNKHNKLNLTQRVG--FFTKEKKTPNDYVNKPTILQGFPERVVD--------FSVGSYHSGV--ILESGQVMIFGRN 712          

Query: 3013 ISLGKNHALILTESGSLYSAGTNECGQLGIENHVLKQNSFVNKNQCLSIIHPMLINIELNSDECIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHGDIDDQFVSKRL--IFDFNNSGSGQEFPIELSMGCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKSLVPNLVDRLPP-AVIHVDTKYFHTVCCTASNEIFTWGIHPNIWQNSLNHEKSHGEISIPESIYTGDLLSNQKIAQISCGTCHASILTDKQFVYCFGSNVWGQLGLGNRK--DNKNLVEVNIPVPIDFVSSDDGITIAMSKSENSTKL 3948
            ++ G  H L LT  G +Y+ G  E G+LG  N              +S   P L+   LN    +  IA G  HS AI       T + HV TWG G +G+LGHGD +DQ   K +  +  +      +   I    G   ++ +T+   V+ +G+  YG+LG        +P  ++ L    V+ V+     +V  T S  ++TWG           H   HG +           L  +KI  I+ G+ H    +D   VY +G N  GQLG G         LV       I  V+     T+A+S S+ S +L
Sbjct: 4141 VNSGGKHCLALTTEGEVYAWGEGEDGKLGHGNR-------------MSYDRPKLVE-HLNG-MSVADIACGSAHSAAI-------TASGHVLTWGKGRYGRLGHGDSEDQLRPKLVEALLGY------RAIDIACGSGDAQTLCITDDDNVWSWGDGDYGKLGRGGSDGCKLPYKIESLAGLGVVKVECGSQFSVALTKSGAVYTWG-------KGDFHRLGHGSVDHVRRPKKVAALQGKKIISIATGSLHCVACSDSGEVYTWGDNDEGQLGDGTVTAIQRPRLVAALQGKHIVKVTCGSAHTLALSTSQLSERL 4422          

Query: 3001 IIRQISL--GKNHALILTESGSLYSAGTNECGQLGIENHVLKQNSFVNKNQCLSIIHPMLINIELNSDECIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHGDIDDQFVSKRLIFDFNNSGSGQEFPIELSMGC--FHSVILTNKGFVYCFGNNSYGQLGVQTLQKSLVPNLVDRLPP-AVIHVDTKYFHTVCCTASNEIFTWGIHPNIWQNSLNHEKSHG---EISIPESIYTGDLLSNQKIAQISCGTCHASILTDKQFVYCFGSNVWGQLGLGNRKDNK 3849
            +++++++  G  HAL LT  G ++S G  E G+LG  N               ++  P L+  E    + I  +A G  HS AI       +    ++TWG G +G+LGHGD   Q   K +      + +G+   ++++ G     ++ LT  G V+ +G+  +G+LG    + S  P+ ++RL    V+ ++     ++  T + E++TWG           +   HG    +  P+ I     L  +++  ++ G  H   +TD   VY +G N  GQ G GN   NK
Sbjct: 3072 VVKKVAVHSGGKHALALTLDGKVFSWGEGEDGKLGHGNRT-------------TLDKPRLV--EALRAKKIRDVACGSSHSAAI-------SSQGELYTWGLGEYGRLGHGDNTTQLKPKLV-----TALAGRRV-VQVACGSRDAQTLALTEDGAVFSWGDGDFGKLGRGGSEGSDTPHEIERLSGIGVVQIECGAQFSLALTRAGEVWTWG-------KGDYYRLGHGGDQHVRKPQPIGG---LRGRRVIHVAVGALHCLAVTDAGQVYAWGDNDHGQQGSGNTFVNK 3324          

Query: 3202 CIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHGDIDDQ-------FVSKRLIFDFNNSGSGQEFPIELSMGCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKSLVPNLVDRLPPAVIHVDTKYFHTVCCTASNEIFTWGIHPNIWQNSLNH---EKSHGEISIPESIYTGDLLSNQKIAQISCGTCHASILTDKQFVYCFGSN 3807
            C+ S+  G  +S AI       T   ++ TWG G + +LGHG+ DD+        +S  ++ D           + L  G  HS+ LT++G V+ +G+  YG+LG      SL P LV+ L P V  V      +V  ++  +++TWG         L H   E+S    S+P  + +   L +++I  ++    H   L+    V+ +G N
Sbjct:  669 CVQSVYCGCSYSAAI-------TCGGNLLTWGRGTYARLGHGNSDDRSLPTLVVALSDHMVVD-----------VALGSGDAHSLALTSEGLVFAWGDGDYGKLGNGNCNGSLQPILVESL-PRVQRVFAGSQFSVALSSEGQLYTWGK-----ATCLGHQLVERSVQGCSVPRLVSS---LQHKRIVDVAVSVAHCLALSSSGEVFGWGRN 853          

Query: 3013 ISLGKNHALILTESGSLY---SAGTNECGQLGIEN--HVLKQNSFVNKNQCLSIIHPMLINIELNSDECIFSIAAGDYHSGAIVVSTSHTTQNSH--------VFTWGWGVHGQLG--HGDIDDQFVSKRLIFDFNNSGSGQEFPIELSMGCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKSLVPNLVDRLPPAVIH---VDTKYFHTVCCTASNEIFTWGIHPNIWQNSLNHEKSHGEISIPESIYTGDLLSNQKIAQISCGTCHASILTDKQFVYCFGSNVWGQLGLGN 3834
            +  G +  L++ +  + Y        +C   GI+   H +K   FV + Q   + H +L N +  + E    +  G   +GA  VSTSH    +         V  WG     QLG   G       SK  +  F+ + S    PI ++ G     I++  G VY  G  + G+LG+       +P+ +  L   V+    V +   H +  T   ++F+WG          + +  HG  +  +     + L  +KI  ++CG+ H++ ++ +  +Y +G   +G+LG G+
Sbjct: 2890 VPAGASRVLLMQQVPTYYPWVEVVVKQCQNNGIQCKIHGIK---FVGRRQQPDLQH-ILANAQFLASEYSAGVGPGST-AGAGAVSTSHEEAAAAPEQDLPCTVMVWGLNDKEQLGGLKG-------SKVKVPTFSQTISRLR-PIHIAGGSKSLFIVSQDGKVYACGEGTNGRLGLGVTHNVPLPHQLPVLRQYVVKKVAVHSGGKHALALTLDGKVFSWG-------EGEDGKLGHGNRTTLDKPRLVEALRAKKIRDVACGSSHSAAISSQGELYTWGLGEYGRLGHGD 3161          

Query: 2932 LGFIKEKSNRILLLPKSIE-SGKEIIRQISLGKNHALILTESGSLYSAGTNECGQLGIENHVLKQNSFVNKNQCLSIIHPMLINIELNSDECIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHG---------DIDDQFVSKRLIFDFNNSGSGQEFPIELSMGCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKSLVPNLVDRL------PPAVIHVDTKYFHTVCCTASNEIFTWGIHPNIWQNSLNHEKSHGEISIPESIYTGDLLSNQKIAQISCGTCHASILTDKQFVYCFGSNVWGQLGLG---NRKDNKNLVEVNIPVPIDFVSSDDGITIAMSKSENSTKLFVWGRCGH 3972
            LG I+++    +L P  I  +    ++Q++ G  H L LT +G +Y+ G+N+  QLG        +    K   +S   P L+  EL  D  I  I  G  HS A+       +    V +WG    GQLGH           +  Q V+K +              ++++ G  HS+ LT+ G +Y +G+N YGQLGV +       N   RL      P A I       H+   + S  +F WG + N  Q  LN E +    S P  + T   L    +  ++CG   +  LT++  V+  G+  +GQLG G   N    + ++E+ +   I  V+  +  T+A+  S      F  G  G 
Sbjct:   20 LGGIEDEQ---ILTPSQIPWTPDTAVQQVACGHRHTLFLTATGKVYACGSNDYSQLG--------HDLPTKRPRMS---PFLLIPELQ-DYVIIQICCGSRHSLAL-------SDWGQVLSWGDNDCGQLGHATDKEIVQLPKVVRQLVTKTV--------------VQIACGNNHSLALTSCGELYSWGSNIYGQLGVNSPNDLTHCNYPLRLTTLLGIPLAAIACGGN--HSFLISKSGAVFGWGRN-NCGQLGLNDETNR---SYPTQLKT---LRTLGVRFVACGDEFSVFLTNEGGVFTCGAGAYGQLGHGFSSNEMLPRMVMEL-MGSTITQVACGNRHTLALVPSRGRVYAFGLGSSGQ 339          

Query: 3283 VFTWGWGVHGQLGHGDIDDQFVSKRLIFDFNNSGSGQEFPIELSMGCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKS-------LVPNLVDRLPPAVIHVDTKYFHTVCCTASNEIFTWGIHPNIWQNSLNHEKSHGEISIPESIYTGDLLSNQKIAQISCGTCHASILTDKQFVYCFGSNVWGQLGLGNRKDNKNLVEVNIP--------VPIDFVSSDDGITIAMSKSENSTKLFVWGR--CGH 3972
            ++ WG   HGQLG G I+D+ +       +    + Q+    ++ G  H++ LT  G VY  G+N Y QLG     K        L+P L D +   +I +     H++  +   ++ +WG +       L H      + +P+ +     L  + + QI+CG  H+  LT    +Y +GSN++GQLG+ +  D   L   N P        +P+  ++     +  +SK   S  +F WGR  CG 
Sbjct:    7 LYCWGSTSHGQLGLGGIEDEQILTPSQIPWTPDTAVQQ----VACGHRHTLFLTATGKVYACGSNDYSQLGHDLPTKRPRMSPFLLIPELQDYV---IIQICCGSRHSLALSDWGQVLSWGDNDC---GQLGHATDKEIVQLPKVVRQ---LVTKTVVQIACGNNHSLALTSCGELYSWGSNIYGQLGVNSPND---LTHCNYPLRLTTLLGIPLAAIACGGNHSFLISK---SGAVFGWGRNNCGQ 234          

Query: 2944 KEKSNRILLLPKSIESGKEIIRQISLGKNHALILTESGSLYSAGTNECGQLGIENHVLKQNSFVNKNQCLSIIHPMLINIELNSDECIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHGDIDDQFVSKRLIFDFNNSGSGQEFPIELSM-----------GCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKSLVPNLVDRLPP-AVIHVDTKYFHTVCCTASNEIFTWGIHPNIWQNSLNHEKSHGEISIPESIYTGDLLSNQKIAQISCGTCHA-SILTDKQFVYCFGSNVWGQLGLGNRK 3840
            + + +  LL+P   E    +I QI  G  H+L L++ G + S G N+CGQLG   H   +       Q   ++  ++        + +  IA G+ HS A+       T    +++WG  ++GQLG    +D               +   +P+ L+            G  HS +++  G V+ +G N+ GQLG+        P  +  L    V  V      +V  T    +FT G         L H  S  E+ +P  +     L    I Q++CG  H  +++  +  VY FG    GQLG  + K
Sbjct:   80 RPRMSPFLLIP---ELQDYVIIQICCGSRHSLALSDWGQVLSWGDNDCGQLG---HATDKEIV----QLPKVVRQLVT-------KTVVQIACGNNHSLAL-------TSCGELYSWGSNIYGQLGVNSPNDL--------------THCNYPLRLTTLLGIPLAAIACGGNHSFLISKSGAVFGWGRNNCGQLGLNDETNRSYPTQLKTLRTLGVRFVACGDEFSVFLTNEGGVFTCGAGA---YGQLGHGFSSNEM-LPRMVME---LMGSTITQVACGNRHTLALVPSRGRVYAFGLGSSGQLGTRSTK 346          

Query: 3004 IRQISLGKNHALILTESGSLYSAGTNECGQLGIENHVLKQNSFVNKNQCLSIIHPMLINIELNSDECIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHGDIDDQFVSKRLIFDFNNSGSGQEFPIELSMGCFHSVILT-NKGFVYCFGNNSYGQLGVQTLQKSLVPNLV 3534
            +  I+ G NH+ ++++SG+++  G N CGQLG+ +      S+  + + L  +              +  +A GD  S  +       T    VFT G G +GQLGHG   ++ +  R++ +   S   Q     ++ G  H++ L  ++G VY FG  S GQLG ++ +  ++P +V
Sbjct:  205 LAAIACGGNHSFLISKSGAVFGWGRNNCGQLGLNDET--NRSYPTQLKTLRTLG-------------VRFVACGDEFSVFL-------TNEGGVFTCGAGAYGQLGHGFSSNEML-PRMVMELMGSTITQ-----VACGNRHTLALVPSRGRVYAFGLGSSGQLGTRSTKSLMLPQVV 354          

Query: 2932 LGFIKEKSNRILLLPKSIE-SGKEIIRQISLGKNHALILTESGSLYSAGTNECGQLGIENHVLKQNSFVNKNQCLSIIHPMLINIELNSDECIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHG---------DIDDQFVSKRLIFDFNNSGSGQEFPIELSMGCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKSLVPNLVDRL------PPAVIHVDTKYFHTVCCTASNEIFTWGIHPNIWQNSLNHEKSHGEISIPESIYTGDLLSNQKIAQISCGTCHASILTDKQFVYCFGSNVWGQLGLG---NRKDNKNLVEVNIPVPIDFVSSDDGITIAMSKSENSTKLFVWGRCGH 3972
            LG I+++    +L P  I  +    ++Q++ G  H L LT +G +Y+ G+N+  QLG +               L    P+LI  EL  D  I  I  G  HS A+       +    V +WG    GQLGH           +  Q V+K +              ++++ G  HS+ LT+ G +Y +G+N YGQLGV +       N   RL      P A I       H+   + S  +F WG + N  Q  LN E +    S P  + T   L    +  ++CG   +  LT++  V+  G+  +GQLG G   N    + ++E+ +   I  V+  +  T+A+  S      F  G  G 
Sbjct:   20 LGGIEDEQ---ILTPSQIPWTPDTAVQQVACGHRHTLFLTATGKVYACGSNDYSQLGHD---------------LPTKRPLLIP-ELQ-DYVIIQICCGSRHSLAL-------SDWGQVLSWGDNDCGQLGHATDKEIVQLPKVVRQLVTKTV--------------VQIACGNNHSLALTSCGELYSWGSNIYGQLGVNSPNDLTHCNYPLRLTTLLGIPLAAIACGGN--HSFLISKSGAVFGWGRN-NCGQLGLNDETNR---SYPTQLKT---LRTLGVRFVACGDEFSVFLTNEGGVFTCGAGAYGQLGHGFSSNEMLPRMVMEL-MGSTITQVACGNRHTLALVPSRGRVYAFGLGSSGQ 334          

Query: 3283 VFTWGWGVHGQLGHGDIDDQFVSKRLIFDFNNSGSGQEFPIELSMGCFHSVILTNKGFVYCFGNNSYGQLG--VQTLQKSLVPNLVDRLPPAVIHVDTKYFHTVCCTASNEIFTWGIHPNIWQNSLNHEKSHGEISIPESIYTGDLLSNQKIAQISCGTCHASILTDKQFVYCFGSNVWGQLGLGNRKDNKNLVEVNIP--------VPIDFVSSDDGITIAMSKSENSTKLFVWGR--CGH 3972
            ++ WG   HGQLG G I+D+ +       +    + Q+    ++ G  H++ LT  G VY  G+N Y QLG  + T +  L+P L D +   +I +     H++  +   ++ +WG +       L H      + +P+ +     L  + + QI+CG  H+  LT    +Y +GSN++GQLG+ +  D   L   N P        +P+  ++     +  +SK   S  +F WGR  CG 
Sbjct:    7 LYCWGSTSHGQLGLGGIEDEQILTPSQIPWTPDTAVQQ----VACGHRHTLFLTATGKVYACGSNDYSQLGHDLPTKRPLLIPELQDYV---IIQICCGSRHSLALSDWGQVLSWGDNDC---GQLGHATDKEIVQLPKVVRQ---LVTKTVVQIACGNNHSLALTSCGELYSWGSNIYGQLGVNSPND---LTHCNYPLRLTTLLGIPLAAIACGGNHSFLISK---SGAVFGWGRNNCGQ 229          

Query: 2953 SNRILLLPKSIESGKEIIRQISLGKNHALILTESGSLYSAGTNECGQLGIENHVLKQNSFVNKNQCLSIIHPMLINIELNSDECIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHGDIDDQFVSKRLIFDFNNSGSGQEFPIELSM-----------GCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKSLVPNLVDRLPP-AVIHVDTKYFHTVCCTASNEIFTWGIHPNIWQNSLNHEKSHGEISIPESIYTGDLLSNQKIAQISCGTCHA-SILTDKQFVYCFGSNVWGQLGLGNRK 3840
            + R LL+P   E    +I QI  G  H+L L++ G + S G N+CGQLG   H   +       Q   ++  ++        + +  IA G+ HS A+       T    +++WG  ++GQLG    +D               +   +P+ L+            G  HS +++  G V+ +G N+ GQLG+        P  +  L    V  V      +V  T    +FT G         L H  S  E+ +P  +     L    I Q++CG  H  +++  +  VY FG    GQLG  + K
Sbjct:   78 TKRPLLIP---ELQDYVIIQICCGSRHSLALSDWGQVLSWGDNDCGQLG---HATDKEIV----QLPKVVRQLVT-------KTVVQIACGNNHSLAL-------TSCGELYSWGSNIYGQLGVNSPNDL--------------THCNYPLRLTTLLGIPLAAIACGGNHSFLISKSGAVFGWGRNNCGQLGLNDETNRSYPTQLKTLRTLGVRFVACGDEFSVFLTNEGGVFTCGAGA---YGQLGHGFSSNEM-LPRMVME---LMGSTITQVACGNRHTLALVPSRGRVYAFGLGSSGQLGTRSTK 341          

Query: 3004 IRQISLGKNHALILTESGSLYSAGTNECGQLGIENHVLKQNSFVNKNQCLSIIHPMLINIELNSDECIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHGDIDDQFVSKRLIFDFNNSGSGQEFPIELSMGCFHSVILT-NKGFVYCFGNNSYGQLGVQTLQKSLVPNLV 3534
            +  I+ G NH+ ++++SG+++  G N CGQLG+ +      S+  + + L  +              +  +A GD  S  +       T    VFT G G +GQLGHG   ++ +  R++ +   S   Q     ++ G  H++ L  ++G VY FG  S GQLG ++ +  ++P +V
Sbjct:  200 LAAIACGGNHSFLISKSGAVFGWGRNNCGQLGLNDET--NRSYPTQLKTLRTLG-------------VRFVACGDEFSVFL-------TNEGGVFTCGAGAYGQLGHGFSSNEMLP-RMVMELMGSTITQ-----VACGNRHTLALVPSRGRVYAFGLGSSGQLGTRSTKSLMLPQVV 349          

Query: 2932 LGFIKEKSNRILLLPKSIE-SGKEIIRQISLGKNHALILTESGSLYSAGTNECGQLGIENHVLKQNSFVNKNQCLSIIHPMLINIELNSDECIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHG---------DIDDQFVSKRLIFDFNNSGSGQEFPIELSMGCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKSLVPNLVDRL------PPAVIHVDTKYFHTVCCTASNEIFTWGIHPNIWQNSLNHEKSHGEISIPESIYTGDLLSNQKIAQISCGTCHASILTDKQFVYCFGSNVWGQLGLG---NRKDNKNLVEVNIPVPIDFVSSDDGITIAMSKSENSTKLFVWGRCGH 3972
            LG I+++    +L P  I  +    ++Q++ G  H L LT +G +Y+ G+N+  QLG +               L    P+LI  EL  D  I  I  G  HS A+       +    V +WG    GQLGH           +  Q V+K +              ++++ G  HS+ LT+ G +Y +G+N YGQLGV +       N   RL      P A I       H+   + S  +F WG + N  Q  LN E +    S P  + T   L    +  ++CG   +  LT++  V+  G+  +GQLG G   N    + ++E+ +   I  V+  +  T+A+  S      F  G  G 
Sbjct:   20 LGGIEDEQ---ILTPSQIPWTPDTAVQQVACGHRHTLFLTATGKVYACGSNDYSQLGHD---------------LPTKRPLLIP-ELQ-DYVIIQICCGSRHSLAL-------SDWGQVLSWGDNDCGQLGHATDKEIVQLPKVVRQLVTKTV--------------VQIACGNNHSLALTSCGELYSWGSNIYGQLGVNSPNDLTHCNYPLRLTTLLGIPLAAIACGGN--HSFLISKSGAVFGWGRN-NCGQLGLNDETNR---SYPTQLKT---LRTLGVRFVACGDEFSVFLTNEGGVFTCGAGAYGQLGHGFSSNEMLPRMVMEL-MGSTITQVACGNRHTLALVPSRGRVYAFGLGSSGQ 334          

Query: 3283 VFTWGWGVHGQLGHGDIDDQFVSKRLIFDFNNSGSGQEFPIELSMGCFHSVILTNKGFVYCFGNNSYGQLG--VQTLQKSLVPNLVDRLPPAVIHVDTKYFHTVCCTASNEIFTWGIHPNIWQNSLNHEKSHGEISIPESIYTGDLLSNQKIAQISCGTCHASILTDKQFVYCFGSNVWGQLGLGNRKDNKNLVEVNIP--------VPIDFVSSDDGITIAMSKSENSTKLFVWGR--CGH 3972
            ++ WG   HGQLG G I+D+ +       +    + Q+    ++ G  H++ LT  G VY  G+N Y QLG  + T +  L+P L D +   +I +     H++  +   ++ +WG +       L H      + +P+ +     L  + + QI+CG  H+  LT    +Y +GSN++GQLG+ +  D   L   N P        +P+  ++     +  +SK   S  +F WGR  CG 
Sbjct:    7 LYCWGSTSHGQLGLGGIEDEQILTPSQIPWTPDTAVQQ----VACGHRHTLFLTATGKVYACGSNDYSQLGHDLPTKRPLLIPELQDYV---IIQICCGSRHSLALSDWGQVLSWGDNDC---GQLGHATDKEIVQLPKVVRQ---LVTKTVVQIACGNNHSLALTSCGELYSWGSNIYGQLGVNSPND---LTHCNYPLRLTTLLGIPLAAIACGGNHSFLISK---SGAVFGWGRNNCGQ 229          

Query: 2953 SNRILLLPKSIESGKEIIRQISLGKNHALILTESGSLYSAGTNECGQLGIENHVLKQNSFVNKNQCLSIIHPMLINIELNSDECIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHGDIDDQFVSKRLIFDFNNSGSGQEFPIELSM-----------GCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKSLVPNLVDRLPP-AVIHVDTKYFHTVCCTASNEIFTWGIHPNIWQNSLNHEKSHGEISIPESIYTGDLLSNQKIAQISCGTCHA-SILTDKQFVYCFGSNVWGQLGLGNRK 3840
            + R LL+P   E    +I QI  G  H+L L++ G + S G N+CGQLG   H   +       Q   ++  ++        + +  IA G+ HS A+       T    +++WG  ++GQLG    +D               +   +P+ L+            G  HS +++  G V+ +G N+ GQLG+        P  +  L    V  V      +V  T    +FT G         L H  S  E+ +P  +     L    I Q++CG  H  +++  +  VY FG    GQLG  + K
Sbjct:   78 TKRPLLIP---ELQDYVIIQICCGSRHSLALSDWGQVLSWGDNDCGQLG---HATDKEIV----QLPKVVRQLVT-------KTVVQIACGNNHSLAL-------TSCGELYSWGSNIYGQLGVNSPNDL--------------THCNYPLRLTTLLGIPLAAIACGGNHSFLISKSGAVFGWGRNNCGQLGLNDETNRSYPTQLKTLRTLGVRFVACGDEFSVFLTNEGGVFTCGAGA---YGQLGHGFSSNEM-LPRMVME---LMGSTITQVACGNRHTLALVPSRGRVYAFGLGSSGQLGTRSTK 341          

Query: 3004 IRQISLGKNHALILTESGSLYSAGTNECGQLGIENHVLKQNSFVNKNQCLSIIHPMLINIELNSDECIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHGDIDDQFVSKRLIFDFNNSGSGQEFPIELSMGCFHSVILT-NKGFVYCFGNNSYGQLGVQTLQKSLVPNLV 3534
            +  I+ G NH+ ++++SG+++  G N CGQLG+ +      S+  + + L  +              +  +A GD  S  +       T    VFT G G +GQLGHG   ++ +  R++ +   S   Q     ++ G  H++ L  ++G VY FG  S GQLG ++ +  ++P +V
Sbjct:  200 LAAIACGGNHSFLISKSGAVFGWGRNNCGQLGLNDET--NRSYPTQLKTLRTLG-------------VRFVACGDEFSVFL-------TNEGGVFTCGAGAYGQLGHGFSSNEMLP-RMVMELMGSTITQ-----VACGNRHTLALVPSRGRVYAFGLGSSGQLGTRSTKSLMLPQVV 349          

Query: 3004 IRQISLGKNHALILTESGSLYSAGTNECGQLGIENHVLKQNSFVNKNQCLSIIHPMLINIELNSDECIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHGDIDD----QFVSKRLIFDFNNSGSGQEFPIELSMGCFHSVILTNK-----------GFVYCFGNNSYGQLGVQTLQ----KSLVPNLVDRLPPAVIHVDTKYFHTVCCTASNEIFTWGIHP 3633
            +  I  G+ H LILT +G LYS G N   QLGI  H+               + PML+      +  I  + AG YH+ A+         +  ++ WGWG++GQLG G  ++    Q VS    F F          +++S+G  H+++L                ++ FG+N +GQLG         K+ +P  ++    ++  + TK+F  +     + +FTWG  P
Sbjct: 1175 VHAIKCGRQHTLILTNNG-LYSLGNNNLCQLGIGRHMQM------------ALQPMLVTALDGMN--ITMLEAGQYHNAAVA--------DGKLYMWGWGIYGQLGQGSCENIATPQLVS---FFKFKKI-------LQISLGHAHTLVLCGAPNSHMEANHCGNELFVFGSNHFGQLGTGNSDHGDTKTNLPVRLEVGDCSLRLIHTKFFTNLAVDEQDRLFTWGSSP 1370          

Query: 3427 HSVILTNKGFVYCFGNNSYGQLGV-QTLQKSLVPNLVDRLPPAVIHV--DTKYFHTVCCTASNEIFTWGIHPNIWQNSLNHEKSHGEISIPESIYTGDLLSNQKIAQISCGTCHASILTDK-----------QFVYCFGSNVWGQLGLGNRKDNKNLVEVNIPVPIDFVSSDDGITIAMSK------SENSTKLFVWGRCGHSL 3978
            H++ILTN G +Y  GNN+  QLG+ + +Q +L P LV  L    I +    +Y +         ++ WGI+  + Q S  +      I+ P+ +        +KI QIS G  H  +L                ++ FGSN +GQLG GN        + N+PV ++    D  + +  +K       +   +LF WG    +L
Sbjct: 1184 HTLILTNNG-LYSLGNNNLCQLGIGRHMQMALQPMLVTALDGMNITMLEAGQYHNAAVADGKLYMWGWGIYGQLGQGSCEN------IATPQLV---SFFKFKKILQISLGHAHTLVLCGAPNSHMEANHCGNELFVFGSNHFGQLGTGNSDHGD--TKTNLPVRLEV--GDCSLRLIHTKFFTNLAVDEQDRLFTWGSSPQAL 1373          

Query: 3004 IRQISLGKNHALILTESGSLYSAGTNECGQLGIENHVLKQNSFVNKNQCLSIIHPMLINIELNSDECIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHGDIDDQFVSKRLI---------------------------FDFNNSGSGQ--------------------EFPI-ELSMGCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKSLVPNLVDRL-PPAVIHVDTKYFHTVCCTASNEIFTWGIHPNIWQNSLNHEKSHGEISIPESIYTGDLLSNQKIAQISCGTCHA-SILTDKQFVYCFGSNVWGQLGLGNRKDNKNLVEVNIPVPI 3882
            +++++ G  H+L L   GS+Y+ G+N CGQLG +    K  S            P L+   L++ + I  ++ G  HS A+        +   VF WG G  GQLG G  ++     RLI                           F +  + SGQ                      P+ ++S G  HS  L+  G V+ +G NS GQLG+   Q   VP  +  L    V+++     HT   T    +FT+G   N  +  L H+ +  E  +P  +     L   +++QI+CG  H  + +     +Y FG N  GQLG G R   K+      PVP+
Sbjct:   36 LKEVACGNQHSLFLLHDGSVYTCGSNSCGQLGHD----KGGS-----------RPELVG-ALDAQK-ISGVSCGQAHSLAV-------NEQGQVFAWGAGDGGQLGLGTAEEAVRVPRLIKKLCEHRISQVMCGNHHCIALSKDGQLFVWGENSSGQLGLGKGEPSTLSPQPLKSLCGIPLTQISAGGDHSFALSFSGAVFGWGKNSAGQLGLNDEQDRAVPCHIKFLRSQKVVYISCGEEHTAALTKEGGLFTFG---NGSKGQLGHDSTRNE-PLPRRVME---LMGTEVSQIACGRNHTLAFVPSTGLIYAFGCNTQGQLGTGIRGSAKS------PVPV 341          

Query: 3004 IRQISLGKNHALILTESGSLYSAGTNECGQLGIENHVLKQNSFVNKNQCLSIIHPMLINIELNSDECIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHGDIDDQFVSKRLIFDFNNSGSGQEFPIELSMGCFHSV-ILTNKGFVYCFGNNSYGQLGVQTLQKSLVPNLVDRLPPAVIHVDTKYFHTVCCTASNEIFTWGIH 3630
            + QIS G +H+  L+ SG+++  G N  GQLG+ +   +Q+  V          P  I   L S + ++ I+ G+ H+ A+       T+   +FT+G G  GQLGH    ++ + +R++       S      +++ G  H++  + + G +Y FG N+ GQLG      +  P  V  + P  I     Y  T  CT + +I + G H
Sbjct:  192 LTQISAGGDHSFALSFSGAVFGWGKNSAGQLGLND---EQDRAV----------PCHIKF-LRSQKVVY-ISCGEEHTAAL-------TKEGGLFTFGNGSKGQLGHDSTRNEPLPRRVMELMGTEVS------QIACGRNHTLAFVPSTGLIYAFGCNTQGQLGTGIRGSAKSPVPVSNIQPLCI--GNAYTRTEHCTIA-KIHSGGDH 370          

Query: 3202 CIF------SIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGH----------GDIDDQFVSKRLIFDFNNSGSGQEFPIELSMGCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKSL-VPNLVDRLPPAVI-HVDTKYFHTVCCTASNEIFTWGIHPNIWQNSLNHEKSHGEISI----PESIYTGDL--LSNQKIAQISCGTCHASILTDKQFVYCFGSNVWGQLGLGNRKDNKNLVEVNIPVPIDFVSSDDGITIAMSKSENST-----KLFVWG 3960
            C+F       +A G+ HS  ++        +  V+T G    GQLGH          G +D Q +S                   +S G  HS+ +  +G V+ +G    GQLG+ T ++++ VP L+ +L    I  V     H +  +   ++F WG            E S G++ +    P ++    L  L    + QIS G  H+  L+    V+ +G N  GQLGL + +D        +P  I F+ S   + I+  +   +       LF +G
Sbjct:   29 CVFDGRGLKEVACGNQHSLFLL-------HDGSVYTCGSNSCGQLGHDKGGSRPELVGALDAQKISG------------------VSCGQAHSLAVNEQGQVFAWGAGDGGQLGLGTAEEAVRVPRLIKKLCEHRISQVMCGNHHCIALSKDGQLFVWG------------ENSSGQLGLGKGEPSTLSPQPLKSLCGIPLTQISAGGDHSFALSFSGAVFGWGKNSAGQLGLNDEQDRA------VPCHIKFLRSQKVVYISCGEEHTAALTKEGGLFTFG 267          

Query: 2998 EIIRQISLGKNHALILTESGSLYSAGTNECGQLGIENHVLKQNSFVNKNQCLSIIHPMLINIELNSDECIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHGDIDDQFVSKRLIFDFNNSGSGQEFPIE-LSMGCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKSLVPNLVDRLPPAVIHVDTKYFHTVCCTASNEIFTWGIHPNIWQNSLNHEKSHGEISIPESIYTGDLLSNQ------KIAQISCGTCHASILTDKQFVYCFGSNVWGQLGLGNRKDNKNLVEVNIPVPIDFVSSDDGITIAMSKSENSTKL---------FVWGRCGH-SLIQEHIKNPVSDTLKPQLLIEYQHVVDNHLAWKNCFGIDTVVNGIPKIISKKQLMI 4143
            ++  +IS G  H  ++TE+G L+  G+N  GQLG     L   + VNK  C+  +    + +           A G  H+   +V TS      +++  G    GQLG GD +D+  S  L+  FN  G     PI+ L+ G   S  LT  G +Y +G+NS GQ+G+     +L P  V  +   V  V   Y+H+   T    ++T+G            EK  G++ +         +  Q      ++ Q++CG  H   LT+ + VY FG   +GQLG G       + E  +P  ++      G     +  EN T L         F  GR G   L +E+  N    TL P+ L  + H V        C G   +V   P+      L++
Sbjct:   36 DVPLRISCGDEHTALVTENGKLFMFGSNNWGQLG-----LGTKTTVNKPTCVKALKSERVKL----------TACGRTHT---LVFTSR----GNLYACGGNNEGQLGLGDCNDR-TSFHLVEFFNKQG-----PIKMLAAGSNTSAALTQDGRLYMWGDNSEGQIGLGKESNALTPQEVS-VGKRVFWVSCGYYHSAFVTVDGALYTFG------------EKDSGKLGLSTEKLANHKVPQQVTDIPDRVVQVACGGGHTVALTENE-VYSFGLGQFGQLGHGTF-----IFESRLPRVVEHFRK--GRVKHAACGENHTALITDNGLLYTFGDGRHGKLGLGEENFTNQFKPTLCPRFLDYHVHSV-------TCGGCHMLVLAKPRTERPDDLIL 378          

Query: 3325 GDIDDQFVSKRLIFDFNNSGSGQ----------EFPIELSMGCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKSLVPNLVDRLPPAVIHVDTKYFHTVCCTASNEIFTWGIHPNIWQNSLNHEK--SHGEISIPESIYTGDLLSNQ-KIAQISCGTCHASILTDKQFVYCFGSNVWGQLGLGNRKDNKNLVEVNIPVPIDFVS 3894
            G+ +D+      +F F  S              + P+ +S G  H+ ++T  G ++ FG+N++GQLG+ T      P  V  L    + +      T C      +FT     N++    N+E     G+ +   S +  +  + Q  I  ++ G+  ++ LT    +Y +G N  GQ+GLG   +     EV++   + +VS
Sbjct:    3 GETEDEIPESGAVFTFGKSKFADNAPSKFWLKNDVPLRISCGDEHTALVTENGKLFMFGSNNWGQLGLGTKTTVNKPTCVKALKSERVKL------TACGRTHTLVFT--SRGNLYACGGNNEGQLGLGDCNDRTSFHLVEFFNKQGPIKMLAAGSNTSAALTQDGRLYMWGDNSEGQIGLGKESNALTPQEVSVGKRVFWVS 197          

Query: 2998 EIIRQISLGKNHALILTESGSLYSAGTNECGQLGIENHVLKQNSFVNKNQCLSIIHPMLINIELNSDECIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHGDIDDQF------VSKRLIFDFNNSGSGQEFPIELSMGCFHSVILTNKGFVYCFGNNSYGQLGVQT--LQKSLVPNLVDRLPPAVIHVDTKYFHTVCCTASNEIFTWGIHPNIWQNSLNHEKSHGEISIPESIYTGDLLSNQKIAQISCGTCHASILTDKQFVYCFGSNVWGQLGLG 3831
            E ++  + G+ H L+ T  G+LY+ G N  GQLG+               C       L+    N    I  +AAG   S A+       TQ+  ++ WG    GQ+G G   +        V KR+ +              +S G +HS  +T  G +Y FG    G+LG+ T  L    VP  V  +P  V+ V     HTV  T  NE++++G+     Q  L H     E  +P  +   +     ++   +CG  H +++TD   +Y FG    G+LGLG
Sbjct:   88 ERVKLTACGRTHTLVFTSRGNLYACGGNNEGQLGL-------------GDCNDRTSFHLVEF-FNKQGPIKMLAAGSNTSAAL-------TQDGRLYMWGDNSEGQIGLGKESNALTPQEVSVGKRVFW--------------VSCGYYHSAFVTVDGALYTFGEKDSGKLGLSTEKLANHKVPQQVTDIPDRVVQVACGGGHTVALT-ENEVYSFGLG-QFGQ--LGHGTFIFESRLPRVV---EHFRKGRVKHAACGENHTALITDNGLLYTFGDGRHGKLGLG 331          

Query: 3010 QISLGKNHALILTESGSLYSAGTNECGQLGIENHVLKQNSFVNKNQCLSIIHPMLINIELNSDECIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHGDIDDQFVSKRLIFDFNNSGSGQEFPIE-LSMGCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKSLVPNLVDRLPPAVIHVDTKYFHTVCCTASNEIFTWGIHPNIWQNSLNHEKSHGEISIPESIYTGDLLSNQ------KIAQISCGTCHASILTDKQFVYCFGSNVWGQLGLGNRKDNKNLVEVNIPVPIDFVSSDDGITIAMSKSENSTKL---------FVWGRCGH-SLIQEHIKNPVSDTLKPQLLIEYQHVVDNHLAWKNCFGIDTVVNGIPKIISKKQLMI 4143
            +IS G  H  ++TE+G L+  G+N  GQLG     L   + VNK  C+  +    + +           A G  H+   +V TS      +++  G    GQLG GD +D+  S  L+  FN  G     PI+ L+ G   S  LT  G +Y +G+NS GQ+G+     +L P  V  +   V  V   Y+H+   T    ++T+G            EK  G++ +         +  Q      ++ Q++CG  H   LT+ + VY FG   +GQLG G       + E  +P  ++      G     +  EN T L         F  GR G   L +E+  N    TL P+ L  + H V        C G   +V   P+      L++
Sbjct:   40 RISCGDEHTALVTENGKLFMFGSNNWGQLG-----LGTKTTVNKPTCVKALKSERVKL----------TACGRTHT---LVFTSR----GNLYACGGNNEGQLGLGDCNDR-TSFHLVEFFNKQG-----PIKMLAAGSNTSAALTQDGRLYMWGDNSEGQIGLGKESNALTPQEVS-VGKRVFWVSCGYYHSAFVTVDGALYTFG------------EKDSGKLGLSTEKLANHKVPQQVTDIPDRVVQVACGGGHTVALTENE-VYSFGLGQFGQLGHGTF-----IFESRLPRVVEHFRK--GRVKHAACGENHTALITDNGLLYTFGDGRHGKLGLGEENFTNQFKPTLCPRFLDYHVHSV-------TCGGCHMLVLAKPRTERPDDLIL 378          

Query: 3325 GDIDDQFVSKRLIFDFNNSGSGQ----------EFPIELSMGCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKSLVPNLVDRLPPAVIHVDT-KYFHTVCCTASNEIFTWGIHPNIWQNSLNHEKSHGEISIPESIYTGDLLSNQ-KIAQISCGTCHASILTDKQFVYCFGSNVWGQLGLGNRKDNKNLVEVNI 3870
            G+ +D+      +F F  S              + P+ +S G  H+ ++T  G ++ FG+N++GQLG+ T      P  V  L    + +      HT+  T+   ++  G + N  Q  L      G+ +   S +  +  + Q  I  ++ G+  ++ LT    +Y +G N  GQ+GLG   +     EV++
Sbjct:    3 GETEDEIPESGAVFTFGKSKFADNAPSKFWLKNDVPLRISCGDEHTALVTENGKLFMFGSNNWGQLGLGTKTTVNKPTCVKALKSERVKLTACGRTHTLVFTSRGNLYACGGN-NEGQLGL------GDCNDRTSFHLVEFFNKQGPIKMLAAGSNTSAALTQDGRLYMWGDNSEGQIGLGKESNALTPQEVSV 189          

Query: 2932 LGFIKEKSNRILLLPKSIE--SGKEIIRQISLGKNHALILTESGSLYSAGTNECGQLGIENHVLKQNSFVNKNQCLSIIHPMLINIELNSDECIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHGDIDDQFVSKRLIFDFNNSGSGQEFPIELSMGCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKSLV--PNLVDRLPPAVI-HVDTKYFHTVCCTASNEIFTWGIHPNIWQNSLNHEKSHGEISIPESIYTGDLLSNQKIAQISCGTCHASILTDKQFVYCFGSNVWGQLG 3825
            LG I E+   +LL P+  E   GK + R +  G+ H + L E G++Y+ G N+ GQLG E    K    V+ +                  + I +++ G+ H+ A+            VF WG G  GQLG   ++D     R +   +     Q     ++ G +HS+ L   G ++ +G N YGQLG+   Q + V  P ++  L       +     H+   T S  IF WG +    Q  L           P  + T   L +Q++  I CG  H + LT +  V+ FG+  +GQLG
Sbjct:   14 LGGIDEE---VLLEPRRCEFFEGKRV-RDVGCGRRHTVFLLEDGTVYTCGCNDLGQLGHEKARKKPEQVVSLDA-----------------QNIVAVSCGEAHTLAL-------NDKGQVFAWGLGSDGQLGLSIVEDCLRVPRTVKSLSEVHITQ-----VACGYWHSLALARGGEIFSWGQNKYGQLGLGQ-QGACVCSPQVIQSLQGIPFGQISAGGAHSFGLTLSGAIFGWGRN-KFGQLGLGDNDDR---RFPVLLKT---LRSQQVVYICCGEDHTAALTKEGGVFTFGAGGYGQLG 275          

Query: 3283 VFTWGWGVHGQLGHGDIDDQFVSKRLIFDFNNSGSGQEFPIELSMGCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKSLVPNLVDRLPPA-VIHVDTKYFHTVCCTASNEIFTWGIHPNIWQNSLNHEKSHGEISIPESIYTGDLLSNQKIAQISCGTCHASILTDKQFVYCFGSNVWGQLGLGNRKD---NKNLVEVNIPVPIDFVSSDDGITIAMSKSENSTKLFVWGR 3963
            +  WG    GQLG G ID++ + +    +F      ++    +  G  H+V L   G VY  G N  GQLG +  +K   P  V  L    ++ V     HT+      ++F WG+  +     L        + +P ++ +   LS   I Q++CG  H+  L     ++ +G N +GQLGLG +     +  +++    +P   +S+    +  ++    S  +F WGR
Sbjct:    1 MLCWGNASFGQLGLGGIDEEVLLEPRRCEFFEGKRVRD----VGCGRRHTVFLLEDGTVYTCGCNDLGQLGHEKARKK--PEQVVSLDAQNIVAVSCGEAHTLALNDKGQVFAWGLGSD---GQLGLSIVEDCLRVPRTVKS---LSEVHITQVACGYWHSLALARGGEIFSWGQNKYGQLGLGQQGACVCSPQVIQSLQGIPFGQISAGGAHSFGLTL---SGAIFGWGR 216          

Query: 3271 QNSHVFTWGWGVHGQLGHGDI---DDQFVSKRLIFDFNNSGSGQEFPIELSMGCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKSL-VPNLVDRLPPA-VIHVDTKYFHTVCCTASNEIFTWGIHPNIWQNSLNHEKSHGEISIPESIYTGDLLSNQKIAQISCGTCHASILTDKQFVYCFGSNVWGQLGLGNRKDNKNLVEVNIPVPIDFVSSDDGITIAMSKSENST-----KLFVWGRCGHSLIQEHIKNPVSDTLKPQLLIEYQHVVDNHLA 4068
            ++  V+T G    GQLGH       +Q VS     D  N        + +S G  H++ L +KG V+ +G  S GQLG+  ++  L VP  V  L    +  V   Y+H++      EIF+WG +       L   +    +  P+ I +   L      QIS G  H+  LT    ++ +G N +GQLGLG+  D +       PV +  + S   + I   +   +       +F +G  G+  +     N  +  + P+ + E    V + +A
Sbjct:   51 EDGTVYTCGCNDLGQLGHEKARKKPEQVVS----LDAQNI-------VAVSCGEAHTLALNDKGQVFAWGLGSDGQLGLSIVEDCLRVPRTVKSLSEVHITQVACGYWHSLALARGGEIFSWGQNK---YGQLGLGQQGACVCSPQVIQS---LQGIPFGQISAGGAHSFGLTLSGAIFGWGRNKFGQLGLGDNDDRR------FPVLLKTLRSQQVVYICCGEDHTAALTKEGGVFTFGAGGYGQLGH---NSTNHEVNPRKVFELMGSVVSQIA 300          

Query: 2974 PKSIESGKEI-IRQISLGKNHALILTESGSLYSAGTNECGQLGIENHVLKQNSFVNKNQCLSIIHPMLINIELNSDECIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHGDIDDQFVSKRLIFDFNNSGSGQEFPIELSMGCFHSV-ILTNKGFVYCFGNNSYGQLGVQTLQKSLVPNLV 3534
            P+ I+S + I   QIS G  H+  LT SG+++  G N+ GQLG+ ++  ++              P+L+   L S + ++ I  G+ H+ A+       T+   VFT+G G +GQLGH   + + V+ R +F+   S   Q     ++ G  H++  + + G +  FG    GQLG ++    + P  V
Sbjct:  181 PQVIQSLQGIPFGQISAGGAHSFGLTLSGAIFGWGRNKFGQLGLGDNDDRR-------------FPVLLKT-LRSQQVVY-ICCGEDHTAAL-------TKEGGVFTFGAGGYGQLGHNSTNHE-VNPRKVFELMGSVVSQ-----IACGRQHTLAFIPSSGKIDSFGLGGNGQLGTRSTCNRISPTPV 341          

Query: 2974 PKSIESGKEI-IRQISL--GKNHALILTESGSLYSAGTNECGQLGIENHVLKQNSFVNKNQCLSIIHPMLINIELNSDECIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHGDIDDQFVSK--------RLIFDFNNSGSGQEFPIELSMGCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKSLVPNLVDRLPP-AVIHVDTKYFHTVCCTASNEIFTWGIHPNIWQNSLNHEKSHG---EISIPESIYTGDLLSNQKIAQISCGTCHASILTDKQFVYCFGSNVWGQLGLG--NRKDNKNLVEVNIPVPIDFVSSDDGITIAMSKSE--NSTKL 3948
            P  +ES + + IR++++  G  H L L+  G LYS G  E G+LG            N++ C     P +I   L   E +  IAAG  HS  I       T +  ++TWG G +G+LGHGD +DQ   K        R+I     SG  Q            ++ LT+   V+ +G+  YG+LG        VP  +D L    V+ V+     +V  T S  ++TWG           H   HG    +  P  +     L  +K+  I+ G+ H    T+   VY +G N  GQLG G  N      LV       I+ V+     T+A S S+  N+ KL
Sbjct: 4024 PTLLESIQHVFIRKVAVNSGGKHCLALSSEGELYSWGEAEDGKLG----------HGNRSPC---DRPRVIE-SLRGVEVV-DIAAGGAHSACI-------TASGELYTWGKGRYGRLGHGDSEDQLKPKLVEALQGHRVIDVACGSGDAQ------------TLCLTDDDMVWSWGDGDYGKLGRGGSDGCKVPMKIDSLTGLGVVKVECGSQFSVALTKSGAVYTWG-------KGDYHRLGHGSDDHVRRPRQVQG---LQGKKVIAIATGSLHCVCCTEDGEVYTWGDNDEGQLGDGTTNAIQRPRLVAALQGKKINRVACGSAHTLAWSTSKPTNAGKL 4323          

Query: 2974 PKSIESGK-EIIRQISLGKNHALILTESGSLYSAGTNECGQLGIENHVLKQNSFVNKNQCLSIIHPMLINIELNSDECIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHGDIDDQFVSKRLIFDFNNSGSGQEFPIELSMGCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKSLVPNLVDRLP-PAVIHVDTKYFHTVCCTASNEIFTWGIHPNIWQNSLNHEKSHGEISIPESIYTGDLLSNQKIAQISCGTCHA 3762
            P+ IE+ K + IR I+ G +H+  +T SG LYS G  E G+LG  ++  +             + P L+ + L     +  +A G   +  + +     T    VF+WG G  G+LG G  +   + +  I   N  G  Q     +  G   S+ LT  G V+ +G   Y +LG  T      P +V+ L    ++HV     H +  T + ++F WG       ++ + ++ +G  ++         L  QKI +++CG+ H+
Sbjct: 3084 PRLIEALKTKRIRDIACGSSHSAAITSSGELYSWGLGEYGRLGHGDNTTQ-------------LRPKLVKVLLGHR--VVQVACGSRDAQTLAL-----TDEGMVFSWGDGDFGKLGRGGSEGCNIPQN-IERLNGQGVCQ-----IECGAQFSLALTKSGVVWTWGKGDYFRLGHGTDVHVRKPQMVEGLRGKKIVHVAVGALHCLAVTETGQVFAWG-------DNDHGQQGNGTTTVNRKPTLVQGLEGQKITRVACGSSHS 3315          

Query: 2953 SNRILLLPKSIES-GKEIIRQISL--GKNHALILTESGSLYSAGTNECGQLGIENHVLKQNSFVNKNQCLSIIHPMLINIELNSDECIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHGDIDDQFVSKRLIFDFNNSGSGQEFPIELSMGC--FHSVILTNKGFVYCFGNNSYGQLGVQTLQKSLVPNLVDRLP-PAVIHVDTKYFHTVCCTASNEIFTWGIHPNIWQNSLNHEKSHG---EISIPESIYTGDLLSNQKIAQISCGTCHASILTDKQFVYCFGSNVWGQLGLGNRKDNK 3849
            S+  + +P+ I +    +++++++  G  HA+ LT  G ++S G  + G+LG   H  + N             P LI  E    + I  IA G  HS AI       T +  +++WG G +G+LGHGD   Q   K +     +        ++++ G     ++ LT++G V+ +G+  +G+LG    +   +P  ++RL    V  ++     ++  T S  ++TWG               HG    +  P+ +   + L  +KI  ++ G  H   +T+   V+ +G N  GQ G G    N+
Sbjct: 3023 SSGTIPIPRQISALSNYVVKKVAVHSGGRHAMALTVDGKVFSWGEGDDGKLG---HFSRMNC----------DKPRLI--EALKTKRIRDIACGSSHSAAI-------TSSGELYSWGLGEYGRLGHGDNTTQLRPKLVKVLLGHR------VVQVACGSRDAQTLALTDEGMVFSWGDGDFGKLGRGGSEGCNIPQNIERLNGQGVCQIECGAQFSLALTKSGVVWTWG-------KGDYFRLGHGTDVHVRKPQMV---EGLRGKKIVHVAVGALHCLAVTETGQVFAWGDNDHGQQGNGTTTVNR 3292          

Query: 3031 HALILTESGSLYSAGTNECGQLGIENHVLKQNSFVNKNQCLSIIHPMLINIELNSDECIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHGDIDDQFVSKRLIFDFNNSGSGQEFPIELSMGCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKSLVPNLVDRLPPA-VIHVDTKYFHTVCCTASNEIFTWGIHPNIWQNSLNHEKSHG---EISIPESIYTGDLLSNQKIAQISCGTCHASILTDKQFVYCFGSN 3807
            H L L+ +G ++S G  + G+LG  +      +++ +   +S+     +  +      +  IA G  +S AI       T +  + TWG G +G+LGHG  +DQ  +  L+         +   +    G   ++ +T  G V+ +G+  YG+LG         P LV++L    ++ V      +V  T   +++TWG          N    HG    +  P+ +   D L  +++  I+ G+ H   LT++  V+ +GSN
Sbjct:  496 HYLALSVNGEVFSWGCGDGGRLGHGD-----TTYLEEPTMISVFSGRPVGKQ------VVHIACGSTYSAAI-------TADGELHTWGRGNYGRLGHGSSEDQ-TTPMLVTALKGL---KVIDVACGSGDAQTLAVTENGQVWSWGDGDYGKLGRGGSDGCKTPKLVEKLQDLDIVKVCCGSQFSVALTKDGQVYTWG-------KGDNQRLGHGTDEHVRYPKLL---DSLQGKRVVDIAVGSTHCLALTEEGEVHSWGSN 726          

Query: 3028 NHALILTESGSLYSAGTNECGQLGIENHVLKQNSFVNKNQCLSIIHPMLINIELNSDECIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHGDIDDQFVSKRLIFDFNNSGSGQEFPIELSMGCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKSLVPNLVDRL--PPAVIHVDTKYFHTVCCTASNEIFTWGIHPNIWQNSLNHEKSHGEISIPESIYTGDLLSNQKIAQISCGTCHASILTDKQFVYCFGSNVWGQLGLGNRKDNKNLVEVNIPVP--IDFVSSDDGITIAMSKSENSTKLFVWGRC-GHSLIQEHI 3993
            N  L LT++  ++  GTN  G LG  +               SI+ P    I++ S + I S++   Y SG  VV     T +  V++WG   + QLG+G  +      ++  +  N  +     I ++ G  HS++LT  G VY +G N+ GQ+G  +     +P  V        VI +      ++    + E++ WG + N  Q  L    S G    P  I     L   ++ Q+ CG  H   LTD+  +Y +G+N +GQLG GN+ +    V+V +     ++  +     T A +KS+ S ++++WG+C G S+I  H+
Sbjct:   31 NEVLYLTKNDEVFVMGTNSSGCLGTGD-------------AQSILEPR--RIDMLSGKRIVSLS---YGSGPHVVIV---TSDGEVYSWGHNAYSQLGNGSTNQALSPCQVSTNLINKKA-----ISVACGSHHSMVLTCDGEVYAWGYNNSGQVGSGSTANQPIPRKVTSCLQNKTVIGIACGQMSSMAVVDNGEVYAWGYNGN-GQLGLG---SSGNQPTPCRIAA---LQGIRVEQVVCGYAHTLALTDEGVMYAWGANSYGQLGTGNKSNQSYPVQVIVDKERIVEIAACHSSHTSA-AKSQ-SGQVYMWGQCRGQSVITPHL 322          

Query: 2935 GFIKEKSNRILLLPKSIE--SGKEIIRQISLGKN-HALILTESGSLYSAGTNECGQLGIENHVLKQNSFVNKNQCLSIIHPMLINIELNSDECIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHGDIDDQFVSKRLIFDFNNSGSGQEFPIELSMGCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKSLVPNLVDRLPP-AVIHVDTKYFHTVCCTASNEIFTWG 3624
            G +     + +L P+ I+  SGK I+  +S G   H +I+T  G +YS G N   QLG            + NQ LS   P  ++  L + + I S+A G +HS  +       T +  V+ WG+   GQ+G G   +Q + +++     N     +  I ++ G   S+ + + G VY +G N  GQLG+ +      P  +  L    V  V   Y HT+  T    ++ WG
Sbjct:   51 GCLGTGDAQSILEPRRIDMLSGKRIV-SLSYGSGPHVVIVTSDGEVYSWGHNAYSQLGNG----------STNQALS---PCQVSTNLINKKAI-SVACGSHHSMVL-------TCDGEVYAWGYNNSGQVGSGSTANQPIPRKVTSCLQN-----KTVIGIACGQMSSMAVVDNGEVYAWGYNGNGQLGLGSSGNQPTPCRIAALQGIRVEQVVCGYAHTLALTDEGVMYAWG 257          

Query: 3013 ISLGKNHALILTESGSLYSAGTNECGQLGIENHVLKQNSFVNKNQCLSIIHPMLINIELNSDECIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHGDIDDQFVSKRLIFDFNNSGSGQEFPIE-LSMGCFHSVILTNKGFVYCFGNNSYGQLGV--QTLQKSLVPNLVDRLPPAVIHVDTKYFHTVCCTASNEIFTWG 3624
            ++ G +H+++LT  G +Y+ G N  GQ+G         S    NQ +    P  +   L  ++ +  IA G   S A+V        N  V+ WG+  +GQLG G   +Q    R+        + Q   +E +  G  H++ LT++G +Y +G NSYGQLG   ++ Q   V  +VD+     I        +   + S +++ WG
Sbjct:  132 VACGSHHSMVLTCDGEVYAWGYNNSGQVG---------SGSTANQPI----PRKVTSCLQ-NKTVIGIACGQMSSMAVV-------DNGEVYAWGYNGNGQLGLGSSGNQPTPCRI-------AALQGIRVEQVVCGYAHTLALTDEGVMYAWGANSYGQLGTGNKSNQSYPVQVIVDKERIVEIAACHSSHTSAAKSQSGQVYMWG 310          

Query: 3028 NHALILTESGSLYSAGTNECGQLGIENHVLKQNSFVNKNQCLSIIHPMLINIELNSDECIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHGDIDDQFVSKRLIFDFNNSGSGQEFPIELSMGCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKSLVPNLVDRL--PPAVIHVDTKYFHTVCCTASNEIFTWGIHPNIWQNSLNHEKSHGEISIPESIYTGDLLSNQKIAQISCGTCHASILTDKQFVYCFGSNVWGQLGLGNRKDNKNLVEVNIPVP--IDFVSSDDGITIAMSKSENSTKLFVWGRC-GHSLIQEHI 3993
            N  L LT++  ++  GTN  G LG  +               SI+ P    I++ S + I S++   Y SG  VV     T +  V++WG   + QLG+G  +      ++  +  N  +     I ++ G  HS++LT  G VY +G N+ GQ+G  +     +P  V        VI +      ++    + E++ WG + N  Q  L    S G    P  I     L   ++ Q+ CG  H   LTD+  +Y +G+N +GQLG GN+ +    V+V +     ++  +     T A +KS+ S ++++WG+C G S+I  H+
Sbjct:   52 NEVLYLTKNDEVFVMGTNSSGCLGTGD-------------AQSILEPR--RIDMLSGKRIVSLS---YGSGPHVVIV---TSDGEVYSWGHNAYSQLGNGSTNQALSPCQVSTNLINKKA-----ISVACGSHHSMVLTCDGEVYAWGYNNSGQVGSGSTANQPIPRKVTSCLQNKTVIGIACGQMSSMAVVDNGEVYAWGYNGN-GQLGLG---SSGNQPTPCRIAA---LQGIRVEQVVCGYAHTLALTDEGVMYAWGANSYGQLGTGNKSNQSYPVQVIVDKERIVEIAACHSSHTSA-AKSQ-SGQVYMWGQCRGQSVITPHL 343          

Query: 2935 GFIKEKSNRILLLPKSIE--SGKEIIRQISLGKN-HALILTESGSLYSAGTNECGQLGIENHVLKQNSFVNKNQCLSIIHPMLINIELNSDECIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHGDIDDQFVSKRLIFDFNNSGSGQEFPIELSMGCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKSLVPNLVDRLPP-AVIHVDTKYFHTVCCTASNEIFTWG 3624
            G +     + +L P+ I+  SGK I+  +S G   H +I+T  G +YS G N   QLG            + NQ LS   P  ++  L + + I S+A G +HS  +       T +  V+ WG+   GQ+G G   +Q + +++     N     +  I ++ G   S+ + + G VY +G N  GQLG+ +      P  +  L    V  V   Y HT+  T    ++ WG
Sbjct:   72 GCLGTGDAQSILEPRRIDMLSGKRIV-SLSYGSGPHVVIVTSDGEVYSWGHNAYSQLGNG----------STNQALS---PCQVSTNLINKKAI-SVACGSHHSMVL-------TCDGEVYAWGYNNSGQVGSGSTANQPIPRKVTSCLQN-----KTVIGIACGQMSSMAVVDNGEVYAWGYNGNGQLGLGSSGNQPTPCRIAALQGIRVEQVVCGYAHTLALTDEGVMYAWG 278          

Query: 3013 ISLGKNHALILTESGSLYSAGTNECGQLGIENHVLKQNSFVNKNQCLSIIHPMLINIELNSDECIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHGDIDDQFVSKRLIFDFNNSGSGQEFPIE-LSMGCFHSVILTNKGFVYCFGNNSYGQLGV--QTLQKSLVPNLVDRLPPAVIHVDTKYFHTVCCTASNEIFTWG 3624
            ++ G +H+++LT  G +Y+ G N  GQ+G         S    NQ +    P  +   L  ++ +  IA G   S A+V        N  V+ WG+  +GQLG G   +Q    R+        + Q   +E +  G  H++ LT++G +Y +G NSYGQLG   ++ Q   V  +VD+     I        +   + S +++ WG
Sbjct:  153 VACGSHHSMVLTCDGEVYAWGYNNSGQVG---------SGSTANQPI----PRKVTSCLQ-NKTVIGIACGQMSSMAVV-------DNGEVYAWGYNGNGQLGLGSSGNQPTPCRI-------AALQGIRVEQVVCGYAHTLALTDEGVMYAWGANSYGQLGTGNKSNQSYPVQVIVDKERIVEIAACHSSHTSAAKSQSGQVYMWG 331          

Query: 3028 NHALILTESGSLYSAGTNECGQLGIENHVLKQNSFVNKNQCLSIIHPMLINIELNSDECIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHGDIDDQFVSKRLIFDFNNSGSGQEFPIELSMGCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKSLVPNLVDRL--PPAVIHVDTKYFHTVCCTASNEIFTWGIHPNIWQNSLNHEKSHGEISIPESIYTGDLLSNQKIAQISCGTCHASILTDKQFVYCFGSNVWGQLGLGNRKDNKNLVEVNIPVP--IDFVSSDDGITIAMSKSENSTKLFVWGRC-GHSLIQEHI 3993
            N  L LT++  ++  GTN  G LG  +               SI+ P    I++ S + I S++   Y SG  VV     T +  V++WG   + QLG+G  +      ++  +  N  +     I ++ G  HS++LT  G VY +G N+ GQ+G  +     +P  V        VI +      ++    + E++ WG + N  Q  L    S G    P  I     L   ++ Q+ CG  H   LTD+  +Y +G+N +GQLG GN+ +    V+V +     ++  +     T A +KS+ S ++++WG+C G S+I  H+
Sbjct:   43 NEVLYLTKNDEVFVMGTNSSGCLGTGD-------------AQSILEPR--RIDMLSGKRIVSLS---YGSGPHVVIV---TSDGEVYSWGHNAYSQLGNGSTNQALSPCQVSTNLINKKA-----ISVACGSHHSMVLTCDGEVYAWGYNNSGQVGSGSTANQPIPRKVTSCLQNKTVIGIACGQMSSMAVVDNGEVYAWGYNGN-GQLGLG---SSGNQPTPCRIAA---LQGIRVEQVVCGYAHTLALTDEGVMYAWGANSYGQLGTGNKSNQSYPVQVIVDKERIVEIAACHSSHTSA-AKSQ-SGQVYMWGQCRGQSVITPHL 334          

Query: 2935 GFIKEKSNRILLLPKSIE--SGKEIIRQISLGKN-HALILTESGSLYSAGTNECGQLGIENHVLKQNSFVNKNQCLSIIHPMLINIELNSDECIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHGDIDDQFVSKRLIFDFNNSGSGQEFPIELSMGCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKSLVPNLVDRLPP-AVIHVDTKYFHTVCCTASNEIFTWG 3624
            G +     + +L P+ I+  SGK I+  +S G   H +I+T  G +YS G N   QLG            + NQ LS   P  ++  L + + I S+A G +HS  +       T +  V+ WG+   GQ+G G   +Q + +++     N     +  I ++ G   S+ + + G VY +G N  GQLG+ +      P  +  L    V  V   Y HT+  T    ++ WG
Sbjct:   63 GCLGTGDAQSILEPRRIDMLSGKRIV-SLSYGSGPHVVIVTSDGEVYSWGHNAYSQLGNG----------STNQALS---PCQVSTNLINKKAI-SVACGSHHSMVL-------TCDGEVYAWGYNNSGQVGSGSTANQPIPRKVTSCLQN-----KTVIGIACGQMSSMAVVDNGEVYAWGYNGNGQLGLGSSGNQPTPCRIAALQGIRVEQVVCGYAHTLALTDEGVMYAWG 269          

Query: 3013 ISLGKNHALILTESGSLYSAGTNECGQLGIENHVLKQNSFVNKNQCLSIIHPMLINIELNSDECIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHGDIDDQFVSKRLIFDFNNSGSGQEFPIE-LSMGCFHSVILTNKGFVYCFGNNSYGQLGV--QTLQKSLVPNLVDRLPPAVIHVDTKYFHTVCCTASNEIFTWG 3624
            ++ G +H+++LT  G +Y+ G N  GQ+G         S    NQ +    P  +   L  ++ +  IA G   S A+V        N  V+ WG+  +GQLG G   +Q    R+        + Q   +E +  G  H++ LT++G +Y +G NSYGQLG   ++ Q   V  +VD+     I        +   + S +++ WG
Sbjct:  144 VACGSHHSMVLTCDGEVYAWGYNNSGQVG---------SGSTANQPI----PRKVTSCLQ-NKTVIGIACGQMSSMAVV-------DNGEVYAWGYNGNGQLGLGSSGNQPTPCRI-------AALQGIRVEQVVCGYAHTLALTDEGVMYAWGANSYGQLGTGNKSNQSYPVQVIVDKERIVEIAACHSSHTSAAKSQSGQVYMWG 322          

Query: 2956 NRILLLPKSIE--SGKEIIRQISLGKN-HALILTESGSLYSAGTNECGQLGIENHVLKQNSFVNKNQCLSIIHPMLINIELNSDECIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHGDIDDQFVSKRLIFDFNNSGSGQEFPIELSMGCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKSLVP-NLVDRLPPAVIHVDTKYFHTVCCTASNEIFTWGIHPNIWQNSLNHEKSHGEISIPESIYTGDLLSNQKIAQISCGTCHASILTDKQFVYCFGSNVWGQLGLGNRKDNKNLVEVNIPVPIDFVSSDDGITIAMSKSENSTKLFVWGRC-GHSLIQEHI 3993
            N+  ++P+ ++   GK I+  +S G   H L+  E G +YS G N   QLG  N +               + P+ + +EL + + +  +A G +HS A+       T +  VF WG+   GQ+G G   +Q V +R+     +     +  + ++ G   S+ +T+ G VYC+G N  GQLG+      L+P  LV             + H VC                                              I Q+  G  H   L+D+  +Y +G+N  GQLG+GN+ +    V+V     +  V++     I+ +KS+ S ++++WG C G SL+  H+
Sbjct:  128 NQSTIIPRRLDVLCGKRIV-DLSYGSGPHILVCNEDGEVYSWGHNGYSQLGNGNAIQG-------------VAPVQVCMELLAKK-VVQVACGSHHSMAL-------TSDGEVFCWGYNNCGQVGSGTTANQSVPRRVSATLQS-----KVVVSIAAGQSSSMAVTDNGHVYCWGYNGTGQLGIGNTGNQLMPCRLV-------------FAHPVC----------------------------------------------IIQVVLGYAHTLALSDQGVLYAWGANSHGQLGIGNKSNQTAPVKVGTNERMVEVTACHSTNISAAKSQ-SGQVYMWGLCRGQSLLSPHL 391          

Query: 2998 EIIRQISLGKNHALILTESGSLYSAGTNECGQLGIENHVLKQNSFVNKNQCLSIIHPMLINIELNSDECIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHG-DIDDQFVSKRLIFDFNNSGSGQEFPIELSMGCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKSLVPNLVDRL-PPAVIHVDTKYFHTVCCTASNEIFTWGI--HPNIWQNSLNHEKSHGEISIPESIYTGDLLSNQKIAQISCGTCHA-SILTDKQFVYCFGSNVWGQLGLGNRKDNKN 3852
            +II  +S G+ H L L + G ++S G    GQ+G+         ++   +          NI+  SD  I  +A G +HS A+       +++S +F+WG   +GQLG G +I  +   + +      S SG  F   ++ G  HS  LT  G ++ +G N +GQLG+       VP L+  L    +IH+     HT   T    +FT+G   +  +  NS NHE +      P  ++    L    + QI+CG  H  + +     +Y FG    GQLG G+  + K+
Sbjct:   84 QIIVAVSCGEAHTLALNDKGQVFSWGHAVYGQIGLST----AEEYIRVPR----------NIKSLSDVQIVQVACGHHHSLAL-------SKDSDIFSWGQNQYGQLGLGLEIKKECAPRHI-----KSLSGIPFA-HIAAGGGHSFALTISGAIFGWGRNKFGQLGLTDETDRNVPALLKSLRSQKIIHICCGEDHTAALTKEGGVFTFGAGGYGQLGHNSTNHEVN------PRKVFE---LMGSIVTQIACGRQHTLAFVPSSGRIYSFGLGGNGQLGTGSTINRKS 337          

Query: 3004 IRQISLGKNHALILTESGSLYSAGTNECGQLGIENHVLKQNSFVNKNQCLSIIHPMLINIELNSDECIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHGDIDDQFVSKRLIFDFNNSGSGQEFPIELSMGCFHSVILTNKGFVYCFGNNSYGQLGVQ-TLQKSLVPNLVDRLPP-AVIHVDTKYFHTVCCTASNEIFTWGIHPNIWQNSLNHEKSHGEISIPESIYTGDLLSNQKIAQISCGTCHASILTDKQFVYCFGSNVWGQLG 3825
            +R +  G  H + + + G++Y+ G N+ GQLG +    K                    +     + I +++ G+ H+ A+            VF+WG  V+GQ+G    ++     R I   ++        ++++ G  HS+ L+    ++ +G N YGQLG+   ++K   P  +  L      H+     H+   T S  IF WG +    Q  L  E      ++ +S      L +QKI  I CG  H + LT +  V+ FG+  +GQLG
Sbjct:   36 VRDVGCGSRHTVFVLDDGTVYTCGCNDLGQLGHDKSRRKPE-----------------QVGALDAQIIVAVSCGEAHTLAL-------NDKGQVFSWGHAVYGQIGLSTAEEYIRVPRNIKSLSDVQI-----VQVACGHHHSLALSKDSDIFSWGQNQYGQLGLGLEIKKECAPRHIKSLSGIPFAHIAAGGGHSFALTISGAIFGWGRN-KFGQLGLTDETDRNVPALLKS------LRSQKIIHICCGEDHTAALTKEGGVFTFGAGGYGQLG 275          

Query: 3283 VFTWGWGVHGQLGHGDIDDQFV--SKRLIFDFNNSGSGQEFPIELSMGCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKSLVPNLVDRLPPAVI-HVDTKYFHTVCCTASNEIFTWGIHPNIWQNSLNHEKSHGEISIPESIYTGDLLSNQKIAQISCGTCHASILTDKQFVYCFGSNVWGQLGLG---NRKDNKNLVEVNIPVPIDFVSSDDGITIAMSKSENSTKLFVWGR 3963
            +  WG    GQLG G ID++ V   +R  F  N +        ++  G  H+V + + G VY  G N  GQLG    ++   P  V  L   +I  V     HT+      ++F+WG H    Q  L+  + +  I +P +I +   LS+ +I Q++CG  H+  L+    ++ +G N +GQLGLG    ++     ++    +P   +++  G + A++    S  +F WGR
Sbjct:    1 MLCWGNTSFGQLGLGGIDEEVVLEPRRCDFFINKNVR------DVGCGSRHTVFVLDDGTVYTCGCNDLGQLGHDKSRRK--PEQVGALDAQIIVAVSCGEAHTLALNDKGQVFSWG-HAVYGQIGLSTAEEY--IRVPRNIKS---LSDVQIVQVACGHHHSLALSKDSDIFSWGQNQYGQLGLGLEIKKECAPRHIKSLSGIPFAHIAAGGGHSFALTI---SGAIFGWGR 216          

Query: 2971 LPKSIESGKEI-IRQISLGKNHALILTESGSLYSAGTNECGQLGIENHVLKQNSFVNKNQCLSIIHPMLINIELNSDECIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHGDIDDQFVSKRLIFDFNNSGSGQEFPIELSMGCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKSLVPNLVDRLPPAVI-HVDTKYFHTVC-CTASNEIFTWGIHPN 3636
            +P++I+S  ++ I Q++ G +H+L L++   ++S G N+ GQLG+   +        K +C         +I+  S      IAAG  HS A+ +S +       +F WG    GQLG  D  D+ V   L      S   Q+  I +  G  H+  LT +G V+ FG   YGQLG  +    + P  V  L  +++  +     HT+    +S  I+++G+  N
Sbjct:  127 VPRNIKSLSDVQIVQVACGHHHSLALSKDSDIFSWGQNQYGQLGLGLEI--------KKECAPR------HIKSLSGIPFAHIAAGGGHSFALTISGA-------IFGWGRNKFGQLGLTDETDRNVPALL-----KSLRSQKI-IHICCGEDHTAALTKEGGVFTFGAGGYGQLGHNSTNHEVNPRKVFELMGSIVTQIACGRQHTLAFVPSSGRIYSFGLGGN 324          

Query: 3181 IELNSDECIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGH----------GDIDDQFVSKRLIFDFNNSGSGQEFPIELSMGCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKSL-VPNLVDRLPPA-VIHVDTKYFHTVCCTASNEIFTWGIHPNIWQNSLNHEKSHGEIS---IPESIYTGDLLSNQKIAQISCGTCHASILTDKQFVYCFGSNVWGQLGLGNRKDNKNLVEVNIPVPIDFVSSDDGITIAMSKSENST-----KLFVWGRCGHS 3975
            + L    C F I       G     T     +  V+T G    GQLGH          G +D Q +                  + +S G  H++ L +KG V+ +G+  YGQ+G+ T ++ + VP  +  L    ++ V   + H++  +  ++IF+WG      QN         EI     P  I +   LS    A I+ G  H+  LT    ++ +G N +GQLGL +  D       N+P  +  + S   I I   +   +       +F +G  G+ 
Sbjct:   21 VVLEPRRCDFFINKNVRDVGCGSRHTVFVLDDGTVYTCGCNDLGQLGHDKSRRKPEQVGALDAQII------------------VAVSCGEAHTLALNDKGQVFSWGHAVYGQIGLSTAEEYIRVPRNIKSLSDVQIVQVACGHHHSLALSKDSDIFSWG------QNQYGQLGLGLEIKKECAPRHIKS---LSGIPFAHIAAGGGHSFALTISGAIFGWGRNKFGQLGLTDETDR------NVPALLKSLRSQKIIHICCGEDHTAALTKEGGVFTFGAGGYG 272          

Query: 3004 IRQISLGKNHALILTESGSLYSAGTNECGQLGIENHVLKQNSFVNKNQCLSIIHPMLINIELNSDECIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHGDIDDQFVSKRLIFDFNNSGSGQEFPIELSMGCFHSVILTNKGFVYCFGNNSYGQLGV-QTLQKSLVPNLVDRLPP-AVIHVDTKYFHTVCCTASNEIFTWGIHPNIWQNSLNHEKSHGEISIPESIYTGDLLSNQKIAQISCGTCHASILTDKQFVYCFGSNVWGQLGLGNRKDNKN 3852
            I++++ G NH++ L E G +Y+ G N  GQLG E          NK + +  +          +D+ I  +A G+ HS A+       +    +F+WG G  GQLG    +D     RLI   N     Q+  +++S G +H + L   G  + +G NS+GQLG+ +       P  V  L    +  V     H+   + S  +F WG++ N  Q  L+ EK        ES     LL  QK+  ISCG  H ++LT    V+ FG+   GQLG  +  D  N
Sbjct:   36 IKEVACGGNHSVFLLEDGEVYTCGVNTKGQLGHEREG-------NKPEQIGAL----------ADQHIIHVACGESHSLAL-------SDRGQLFSWGAGSDGQLGLMTTEDSVAVPRLIQKLN-----QQTILQVSCGNWHCLALAADGQFFTWGKNSHGQLGLGKEFPSQTSPQRVRSLEGIPLAQVAAGGAHSFALSLSGAVFGWGMN-NAGQLGLSDEKDR------ESPCHVKLLRTQKVVYISCGEEHTAVLTKSGGVFTFGAGSCGQLGHDSVNDEVN 284          

Query: 3193 SDECIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGH---GDIDDQFVSKRLIFDFNNSGSGQEFPIELSMGCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKSL-VPNLVDRL-PPAVIHVDTKYFHTVCCTASNEIFTWGIHPNIWQNSLNHEKSHGEISI---------PESIYTGDLLSNQKIAQISCGTCHASILTDKQFVYCFGSNVWGQLGLGNRKDNKNLVEVNI--PVPIDFVSSDDGITIAMSKSENSTKLFVWGRCGHSLIQEHIKNPVSDTLKPQLLIE 4038
            SD  I  +A G  HS  ++       ++  V+T G    GQLGH   G+  +Q                 +  I ++ G  HS+ L+++G ++ +G  S GQLG+ T + S+ VP L+ +L    ++ V    +H +   A  + FTWG            + SHG++ +         P+ + +   L    +AQ++ G  H+  L+    V+ +G N  GQLGL + KD ++   V +     + ++S  +  T  ++KS      F  G CG     +   + V+D + P+ ++E
Sbjct:   32 SDRSIKEVACGGNHSVFLL-------EDGEVYTCGVNTKGQLGHEREGNKPEQI-----------GALADQHIIHVACGESHSLALSDRGQLFSWGAGSDGQLGLMTTEDSVAVPRLIQKLNQQTILQVSCGNWHCLALAADGQFFTWG------------KNSHGQLGLGKEFPSQTSPQRVRS---LEGIPLAQVAAGGAHSFALSLSGAVFGWGMNNAGQLGLSDEKDRESPCHVKLLRTQKVVYISCGEEHTAVLTKS-GGVFTFGAGSCG-----QLGHDSVNDEVNPRRVLE 290          

Query: 2974 PKSIESGKEI-IRQISLGKNHALILTESGSLYSAGTNECGQLGIENHVLKQNSFVNKNQCLSIIHPMLINIELNSDECIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHGDIDDQFVSKRLIFDFNNSGSGQEFPIELSMGCFHSVILT-NKGFVYCFGNNSYGQLGV 3498
            P+ + S + I + Q++ G  H+  L+ SG+++  G N  GQLG+ +   +++                 +++L   + +  I+ G+ H+  +       T++  VFT+G G  GQLGH  ++D+ V+ R + +   S   Q     ++ G  H++ L  + G +Y FG  + GQLG 
Sbjct:  181 PQRVRSLEGIPLAQVAAGGAHSFALSLSGAVFGWGMNNAGQLGLSDEKDRESP---------------CHVKLLRTQKVVYISCGEEHTAVL-------TKSGGVFTFGAGSCGQLGHDSVNDE-VNPRRVLELMGSEVTQ-----IACGRQHTLALVPSSGLIYAFGCGAKGQLGT 329          

Query: 2971 LPKSIES-GKEIIRQISLGKNHALILTESGSLYSAGTNECGQLGIENHVLKQNSFVNKNQCLSIIHPMLINIELNSDECIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHGDIDDQ--------FVSKRLIFDFNNSGSGQEFPIELSMGCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKSLVPNLV-DRLPPAVIHVDTKYFHTVCCTASNE-IFTWG 3624
            +P+ I+   ++ I Q+S G  H L L   G  ++ G N  GQLG+      Q S   + + L  I              +  +AAG  HS A+ +S +       VF WG    GQLG  D  D+          ++++++              +S G  H+ +LT  G V+ FG  S GQLG  ++   + P  V + +   V  +     HT+    S+  I+ +G
Sbjct:  127 VPRLIQKLNQQTILQVSCGNWHCLALAADGQFFTWGKNSHGQLGLGKEFPSQTS-PQRVRSLEGIP-------------LAQVAAGGAHSFALSLSGA-------VFGWGMNNAGQLGLSDEKDRESPCHVKLLRTQKVVY--------------ISCGEEHTAVLTKSGGVFTFGAGSCGQLGHDSVNDEVNPRRVLELMGSEVTQIACGRQHTLALVPSSGLIYAFG 320          

Query: 3004 IRQISLGKNHALILTESGSLYSAGTNECGQLGIENHVLKQNSFVNKNQCLSIIHPMLINIELNSDECIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHGDIDDQFVSKRLIFDFNNSGSGQEFPIELSMGCFHSVILTNKGFVYCFGNNSYGQLGV-QTLQKSLVPNLVDRLPP-AVIHVDTKYFHTVCCTASNEIFTWGIHPNIWQNSLNHEKSHGEISIPESIYTGDLLSNQKIAQISCGTCHASILTDKQFVYCFGSNVWGQLGLGNRKDNKN 3852
            I++++ G NH++ L E G +Y+ G N  GQLG E          NK + +  +          +D+ I  +A G+ HS A+       +    +F+WG G  GQLG    +D     RLI   N     Q+  +++S G +H + L   G  + +G NS+GQLG+ +       P  V  L    +  V     H+   + S  +F WG++ N  Q  L+ EK        ES     LL  QK+  ISCG  H ++LT    V+ FG+   GQLG  +  D  N
Sbjct:   36 IKEVACGGNHSVFLLEDGEVYTCGVNTKGQLGHEREG-------NKPEQIGAL----------ADQHIIHVACGESHSLAL-------SDRGQLFSWGAGSDGQLGLMTTEDSVAVPRLIQKLN-----QQTILQVSCGNWHCLALAADGQFFTWGKNSHGQLGLGKEFPSQTSPQRVRSLEGIPLAQVAAGGAHSFALSLSGAVFGWGMN-NAGQLGLSDEKDR------ESPCHVKLLRTQKVVYISCGEEHTAVLTKSGGVFTFGAGSCGQLGHDSVNDEVN 284          

Query: 3193 SDECIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGH---GDIDDQFVSKRLIFDFNNSGSGQEFPIELSMGCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKSL-VPNLVDRL-PPAVIHVDTKYFHTVCCTASNEIFTWGIHPNIWQNSLNHEKSHGEISI---------PESIYTGDLLSNQKIAQISCGTCHASILTDKQFVYCFGSNVWGQLGLGNRKDNKNLVEVNI--PVPIDFVSSDDGITIAMSKSENSTKLFVWGRCGHSLIQEHIKNPVSDTLKPQLLIE 4038
            SD  I  +A G  HS  ++       ++  V+T G    GQLGH   G+  +Q                 +  I ++ G  HS+ L+++G ++ +G  S GQLG+ T + S+ VP L+ +L    ++ V    +H +   A  + FTWG            + SHG++ +         P+ + +   L    +AQ++ G  H+  L+    V+ +G N  GQLGL + KD ++   V +     + ++S  +  T  ++KS      F  G CG     +   + V+D + P+ ++E
Sbjct:   32 SDRSIKEVACGGNHSVFLL-------EDGEVYTCGVNTKGQLGHEREGNKPEQI-----------GALADQHIIHVACGESHSLALSDRGQLFSWGAGSDGQLGLMTTEDSVAVPRLIQKLNQQTILQVSCGNWHCLALAADGQFFTWG------------KNSHGQLGLGKEFPSQTSPQRVRS---LEGIPLAQVAAGGAHSFALSLSGAVFGWGMNNAGQLGLSDEKDRESPCHVKLLRTQKVVYISCGEEHTAVLTKS-GGVFTFGAGSCG-----QLGHDSVNDEVNPRRVLE 290          

Query: 2974 PKSIESGKEI-IRQISLGKNHALILTESGSLYSAGTNECGQLGIENHVLKQNSFVNKNQCLSIIHPMLINIELNSDECIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHGDIDDQFVSKRLIFDFNNSGSGQEFPIELSMGCFHSVILT-NKGFVYCFGNNSYGQLG 3495
            P+ + S + I + Q++ G  H+  L+ SG+++  G N  GQLG+ +   +++                 +++L   + +  I+ G+ H+  +       T++  VFT+G G  GQLGH  ++D+ V+ R + +   S   Q     ++ G  H++ L  + G +Y FG  + GQLG
Sbjct:  181 PQRVRSLEGIPLAQVAAGGAHSFALSLSGAVFGWGMNNAGQLGLSDEKDRESP---------------CHVKLLRTQKVVYISCGEEHTAVL-------TKSGGVFTFGAGSCGQLGHDSVNDE-VNPRRVLELMGSEVTQ-----IACGRQHTLALVPSSGLIYAFGCGAKGQLG 328          

Query: 2971 LPKSIES-GKEIIRQISLGKNHALILTESGSLYSAGTNECGQLGIENHVLKQNSFVNKNQCLSIIHPMLINIELNSDECIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHGDIDDQ--------FVSKRLIFDFNNSGSGQEFPIELSMGCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKSLVPNLV-DRLPPAVIHVDTKYFHTVCCTASNE-IFTWG 3624
            +P+ I+   ++ I Q+S G  H L L   G  ++ G N  GQLG+      Q S   + + L  I              +  +AAG  HS A+ +S +       VF WG    GQLG  D  D+          ++++++              +S G  H+ +LT  G V+ FG  S GQLG  ++   + P  V + +   V  +     HT+    S+  I+ +G
Sbjct:  127 VPRLIQKLNQQTILQVSCGNWHCLALAADGQFFTWGKNSHGQLGLGKEFPSQTS-PQRVRSLEGIP-------------LAQVAAGGAHSFALSLSGA-------VFGWGMNNAGQLGLSDEKDRESPCHVKLLRTQKVVY--------------ISCGEEHTAVLTKSGGVFTFGAGSCGQLGHDSVNDEVNPRRVLELMGSEVTQIACGRQHTLALVPSSGLIYAFG 320          

Query: 3004 IRQISLGKNHALILTESGSLYSAGTNECGQLGIENHVLKQNSFVNKNQCLSIIHPMLINIELNSDECIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHGDIDDQFVSKRLIFDFNNSGSGQEFPIELSMGCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKSLVPNLVDRL-PPAVIHVDTKYFHTVCCTASNEIFTWGI--HPNIWQNSLNHEKSHGEISIPESIYTGDLLSNQKIAQISCGTCHAS-ILTDKQFVYCFGSNVWGQLGLGNRKDNK-------NLVEVNIPVPIDFVSSD 3900
            I  ++ G+ H L L + G +Y+ G +  GQLG++             +C+ +      NI+  SD  I  +A G YHS A+       ++ S VF WG   +GQLG G    +  S +LI     S  G  F ++++ G  HS +LT  G ++ +G N +GQLG+       VPNL+  L    ++++     HT   T    +FT+G   +  +  NS +HE +      P  ++    L    + Q++CG  H S  +     +Y FG    GQLG G+  + K       N    N   P D  S D
Sbjct:   86 IVAVACGEAHTLALNDKGQVYAWGLDSDGQLGLQG----------SEECIRVPR----NIKSLSDIQIVQVACGYYHSLAL-------SKASEVFCWGQNKYGQLGLGIDCQKQTSPQLI----KSLLGIPF-MQVAAGGAHSFVLTLSGAIFGWGRNKFGQLGLNDENDRYVPNLLKSLRSQKIVYICCGEDHTAALTKEGGVFTFGAGGYGQLGHNSTSHEIN------PRKVFE---LMGSIVTQVACGRQHTSAFVPSSGRIYSFGLGGNGQLGTGSTSNRKSPFTVKGNWFSYNGQCPQDIGSED 360          

Query: 3283 VFTWGWGVHGQLGHGDIDDQFVSKRLIFDFNNSGSGQEFPIELSMGCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKSLVPNLVDRLPPA-VIHVDTKYFHTVCCTASNEIFTWGIHPNIWQNSLNHEKSHGEISIPESIYTGDLLSNQKIAQISCGTCHASILTDKQFVYCFGSNVWGQLGLG---NRKDNKNLVEVNIPVPIDFVSSDDGITIAMSKSENSTKLFVWGR 3963
            +  WG   +GQLG G ID++ V +    DF  +   ++    +  G  H+V + + G VY  G N  GQLG +  +K   P  V  L    ++ V     HT+      +++ WG+  +     L  + S   I +P +I +   LS+ +I Q++CG  H+  L+    V+C+G N +GQLGLG    ++ +  L++  + +P   V++    +  ++    S  +F WGR
Sbjct:    1 MLCWGNASYGQLGLGGIDEEIVLEPRRSDFFVNKKVRD----VGCGLRHTVFVLDDGTVYTCGCNDLGQLGHEKSRKK--PEQVVALDAQNIVAVACGEAHTLALNDKGQVYAWGLDSD---GQLGLQGSEECIRVPRNIKS---LSDIQIVQVACGYYHSLALSKASEVFCWGQNKYGQLGLGIDCQKQTSPQLIKSLLGIPFMQVAAGGAHSFVLTL---SGAIFGWGR 216          

Query: 2947 EKSNRILLLPKSIESGKEI-IRQISLGKNHALILTESGSLYSAGTNECGQLGIENHVLKQNSFVNKNQCLSIIHPMLINIELNSDECIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHGDIDDQFVSKRLIFDFNNSGSGQEFPIELSMGCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKSLVPNLVDRLPPAVI-HVDTKYFHTVC-CTASNEIFTWGIHPN 3636
            + S   + +P++I+S  +I I Q++ G  H+L L+++  ++  G N+ GQLG+     KQ S            P LI   L        +AAG  HS  + +S +       +F WG    GQLG  D +D++V   L      S   Q+  + +  G  H+  LT +G V+ FG   YGQLG  +    + P  V  L  +++  V     HT     +S  I+++G+  N
Sbjct:  119 QGSEECIRVPRNIKSLSDIQIVQVACGYYHSLALSKASEVFCWGQNKYGQLGLGIDCQKQTS------------PQLIKSLLGIP--FMQVAAGGAHSFVLTLSGA-------IFGWGRNKFGQLGLNDENDRYVPNLL-----KSLRSQKI-VYICCGEDHTAALTKEGGVFTFGAGGYGQLGHNSTSHEINPRKVFELMGSIVTQVACGRQHTSAFVPSSGRIYSFGLGGN 324          

Query: 3004 IRQISLGKNHALILTESGSLYSAGTNECGQLGIENHVLKQNSFVNKNQCLSIIHPMLINIELNSDECIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHGDIDDQFVSKRLIFDFNNSGSGQEFPIELSMGCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKSLVPNLVDRL-PPAVIHVDTKYFHTVCCTASNEIFTWGI--HPNIWQNSLNHEKSHGEISIPESIYTGDLLSNQKIAQISCGTCHAS-ILTDKQFVYCFGSNVWGQLGLGNRKDNK-------NLVEVNIPVPIDFVSSD 3900
            I  ++ G+ H L L + G +Y+ G +  GQLG++             +C+ +      NI+  SD  I  +A G YHS A+       ++ S VF WG   +GQLG G    +  S +LI     S  G  F ++++ G  HS +LT  G ++ +G N +GQLG+       VPNL+  L    ++++     HT   T    +FT+G   +  +  NS +HE +      P  ++    L    + Q++CG  H S  +     +Y FG    GQLG G+  + K       N    N   P D  S D
Sbjct:   86 IVAVACGEAHTLALNDKGQVYAWGLDSDGQLGLQG----------SEECIRVPR----NIKSLSDIQIVQVACGYYHSLAL-------SKASEVFCWGQNKYGQLGLGIDCQKQTSPQLI----KSLLGIPF-MQVAAGGAHSFVLTLSGAIFGWGRNKFGQLGLNDENDRYVPNLLKSLRSQKIVYICCGEDHTAALTKEGGVFTFGAGGYGQLGHNSTSHEIN------PRKVFE---LMGSIVTQVACGRQHTSAFVPSSGRIYSFGLGGNGQLGTGSTSNRKSPFTVKGNWFSYNGQCPQDIGSED 360          

Query: 3283 VFTWGWGVHGQLGHGDIDDQFVSKRLIFDFNNSGSGQEFPIELSMGCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKSLVPNLVDRLPPA-VIHVDTKYFHTVCCTASNEIFTWGIHPNIWQNSLNHEKSHGEISIPESIYTGDLLSNQKIAQISCGTCHASILTDKQFVYCFGSNVWGQLGLG---NRKDNKNLVEVNIPVPIDFVSSDDGITIAMSKSENSTKLFVWGR 3963
            +  WG   +GQLG G ID++ V +    DF  +   ++    +  G  H+V + + G VY  G N  GQLG +  +K   P  V  L    ++ V     HT+      +++ WG+  +     L  + S   I +P +I +   LS+ +I Q++CG  H+  L+    V+C+G N +GQLGLG    ++ +  L++  + +P   V++    +  ++    S  +F WGR
Sbjct:    1 MLCWGNASYGQLGLGGIDEEIVLEPRRSDFFVNKKVRD----VGCGLRHTVFVLDDGTVYTCGCNDLGQLGHEKSRKK--PEQVVALDAQNIVAVACGEAHTLALNDKGQVYAWGLDSD---GQLGLQGSEECIRVPRNIKS---LSDIQIVQVACGYYHSLALSKASEVFCWGQNKYGQLGLGIDCQKQTSPQLIKSLLGIPFMQVAAGGAHSFVLTL---SGAIFGWGR 216          

Query: 2947 EKSNRILLLPKSIESGKEI-IRQISLGKNHALILTESGSLYSAGTNECGQLGIENHVLKQNSFVNKNQCLSIIHPMLINIELNSDECIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHGDIDDQFVSKRLIFDFNNSGSGQEFPIELSMGCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKSLVPNLVDRLPPAVI-HVDTKYFHTVC-CTASNEIFTWGIHPN 3636
            + S   + +P++I+S  +I I Q++ G  H+L L+++  ++  G N+ GQLG+     KQ S            P LI   L        +AAG  HS  + +S +       +F WG    GQLG  D +D++V   L      S   Q+  + +  G  H+  LT +G V+ FG   YGQLG  +    + P  V  L  +++  V     HT     +S  I+++G+  N
Sbjct:  119 QGSEECIRVPRNIKSLSDIQIVQVACGYYHSLALSKASEVFCWGQNKYGQLGLGIDCQKQTS------------PQLIKSLLGIP--FMQVAAGGAHSFVLTLSGA-------IFGWGRNKFGQLGLNDENDRYVPNLL-----KSLRSQKI-VYICCGEDHTAALTKEGGVFTFGAGGYGQLGHNSTSHEINPRKVFELMGSIVTQVACGRQHTSAFVPSSGRIYSFGLGGN 324          

Query: 2998 EIIRQISL---GKNHALILTESGSLYSAGTNECGQLGIENHVLKQNSFVNKNQCLSIIHPMLINIELNSDECIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHGDIDDQFVSKRLIFDFNNSGSGQEFPIELSMGCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKSLVPNLVDRL--PPAVIHVDTKYFHTVCCTASNEIFTWGIHPNIWQNSLNHEKSHGEISIPESIYTGDLLSNQKIAQISCGTCHASILTDKQFVYCFGSNVWGQLGLGNRKDNKNLVEVNIPVPIDFVSSDDGITIAMSKSENSTK-------LFVWGRC-GHSLIQEH 3990
            ++IRQ  +     N  L  T +  ++  GTN  G LG+                 S I P  ++  L   +    IA+  Y SG  +V     T +  VFTWG   + QLG+G  +   V   +  + +N     +  IE++ G +HS++LT+ G V+ +G N+ GQ+G  +     +P  V        V+++      ++    + E++ WG + N  Q  L    S G    P  +     L   ++ +++CG  H  +LTD+  +Y +G+N +GQLG GN+ +       + P P+  V  D  I IA   S +++        +++WG+C G S+I  H
Sbjct:   43 QLIRQACVFGSAGNEVLYTTVNDEIFVLGTNCSGCLGV-------------GDIQSTIEPRRLD-SLTGKK----IASLSYGSGPHIVLA---TTDGEVFTWGHNAYSQLGNGTTNHGLVPCHISTNLSN-----KQVIEVACGSYHSLVLTSDGEVFAWGYNNSGQVGSGSTANQPIPRRVTGCLQNKVVMNIACGQMCSMAVVDTGEVYVWGYNGN-GQLGLG---SSGNQPTPCRVAA---LQGIRVQRVACGYAHTLVLTDEGQIYAWGANSYGQLGTGNKSNQ------SYPTPV-VVEKDRIIEIAACHSAHTSAAKTQGGHVYMWGQCRGQSVILPH 346          

Query: 2971 LPKSIESGKEIIRQISLGKNHALILTESGSLYSAGTNECGQLGIENHVLKQNSFVNKNQCLSIIHPMLINIELNSD-ECIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHGDIDD--QFVSKR---LIFDFNNSGSGQEFPIELSMGCFHSVILTNKGFVYCFGNNSYGQLGVQT-LQKSLVPNLVDRLPPAVIHVDTKYFHTVCCTASNEIFTWGIHPNIWQ------------------------NSLNHEKSHGEISIPESIYTGDL-------LSNQKIAQISCGTCHASILTDKQFVYCFGSNVWGQLGLGNRKDNKNLVEVNIPVPIDFVSSDDGITIAMSKSENSTKLFVWGR 3963
            LP+ +E      R I+ G  H L+L+ SG L + G N  GQ G+  H  +          ++ +H      +++ D   I  IA G +HS  I    S       ++T+GWGV GQLGHG  ++  Q V  R   LI              +++ G  H+V+LT+ G V   G+ SYGQ+GV   ++K      +   P  V  + T Y+H++C T  N +F WG +P   +                         S N       +++P  I   DL         +  I  ++CG  H++++T +  +Y +G  +  QLG GN+ +     +V  P    +V+   G    ++ +++ + +F WG+
Sbjct:  761 LPRVLEYPGGRPRAIACGAEHILVLSSSGQLSAWGGNRFGQCGV-GHSFR----------IANLH------QVDGDWPAIEKIACGQFHSAFICSDGS-------LWTFGWGVWGQLGHGGRNNSNQLVPTRVNGLICKVT----------QIACGRAHTVVLTDTGRVLVCGSGSYGQMGVDDDIKKVFAFTPLPLGPLRVRDIATHYYHSICITEDNRVFEWGRNPQELKMRMFVMKKIRSAQLKNTEDPSSPSPSTNGSTPRVNLNLPAEIPREDLGLREVKHFLDGNIVSVACGLSHSALITSEGTLYTWGKGLDYQLGHGNKNERMEPHQVFEPNGAKWVNVSLGNNHTIASTDDGS-VFAWGK 1094          

Query: 3004 IRQISLGKNHALILTESGSLYSAGTNECGQLGIENHVLKQNSFVNKNQCLSIIHPMLINIELNSDECIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHGDIDDQFVSKRLIFDFNNSGSGQEFPIELSMGCFHSVILTNKGFVYCFGNNSYGQLGV-QTLQKSLVPNLVDRLPP-AVIHVDTKYFHTVCCTASNEIFTWGIHPNIWQNSLNHEKSHGEISIPESIYTGDLLSNQKIAQISCGTCHASILTDKQFVYCFGSNVWGQLGLGNRKDNKN 3852
            +++++ G NH++ L E G +Y+ G N  GQLG E          NK + +  +          +D+ I  +A G+ HS A+       +    +F+WG G  GQLG    +D     RLI   N     Q+  +++S G +H + L   G  + +G NS+GQLG+ +       P  V  L    +  V     H+   + S  +F WG++ N  Q  L+ EK        ES     LL  QK+  ISCG  H ++LT    V+ FG+   GQLG  +  D  N
Sbjct:   36 VKEVACGGNHSVFLLEDGEVYTCGLNTKGQLGHEREG-------NKPEQIGAL----------ADQHIIHVACGESHSLAL-------SDRGQLFSWGAGSDGQLGLMTTEDSVAVPRLIQKLN-----QQTILQVSCGNWHCLALAADGQFFTWGKNSHGQLGLGKEFPSQASPQRVRSLEGIPLAQVAAGGAHSFALSLSGAVFGWGMN-NAGQLGLSDEKDR------ESPCHVKLLRTQKVVYISCGEEHTAVLTKSGGVFTFGAGSCGQLGHDSMNDEVN 284          

Query: 3193 SDECIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGH---GDIDDQFVSKRLIFDFNNSGSGQEFPIELSMGCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKSL-VPNLVDRL-PPAVIHVDTKYFHTVCCTASNEIFTWGIHPNIWQNSLNHEKSHGEISI---------PESIYTGDLLSNQKIAQISCGTCHASILTDKQFVYCFGSNVWGQLGLGNRKDNKNLVEVNI--PVPIDFVSSDDGITIAMSKSENSTKLFVWGRCGHSLIQEHIKNPVSDTLKPQLLIE 4038
            SD  +  +A G  HS  ++       ++  V+T G    GQLGH   G+  +Q                 +  I ++ G  HS+ L+++G ++ +G  S GQLG+ T + S+ VP L+ +L    ++ V    +H +   A  + FTWG            + SHG++ +         P+ + +   L    +AQ++ G  H+  L+    V+ +G N  GQLGL + KD ++   V +     + ++S  +  T  ++KS      F  G CG     +   + ++D + P+ ++E
Sbjct:   32 SDRSVKEVACGGNHSVFLL-------EDGEVYTCGLNTKGQLGHEREGNKPEQI-----------GALADQHIIHVACGESHSLALSDRGQLFSWGAGSDGQLGLMTTEDSVAVPRLIQKLNQQTILQVSCGNWHCLALAADGQFFTWG------------KNSHGQLGLGKEFPSQASPQRVRS---LEGIPLAQVAAGGAHSFALSLSGAVFGWGMNNAGQLGLSDEKDRESPCHVKLLRTQKVVYISCGEEHTAVLTKS-GGVFTFGAGSCG-----QLGHDSMNDEVNPRRVLE 290          

Query: 2974 PKSIESGKEI-IRQISLGKNHALILTESGSLYSAGTNECGQLGIENHVLKQNSFVNKNQCLSIIHPMLINIELNSDECIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHGDIDDQFVSKRLIFDFNNSGSGQEFPIELSMGCFHSV-ILTNKGFVYCFGNNSYGQLGV 3498
            P+ + S + I + Q++ G  H+  L+ SG+++  G N  GQLG+ +   +++                 +++L   + +  I+ G+ H+  +       T++  VFT+G G  GQLGH  ++D+ V+ R + +   S   Q     ++ G  H++  + + G +Y FG  + GQLG 
Sbjct:  181 PQRVRSLEGIPLAQVAAGGAHSFALSLSGAVFGWGMNNAGQLGLSDEKDRESP---------------CHVKLLRTQKVVYISCGEEHTAVL-------TKSGGVFTFGAGSCGQLGHDSMNDE-VNPRRVLELMGSEVTQ-----IACGRQHTLAFVPSSGLIYAFGCGARGQLGT 329          

Query: 2971 LPKSIES-GKEIIRQISLGKNHALILTESGSLYSAGTNECGQLGIENHVLKQNSFVNKNQCLSIIHPMLINIELNSDECIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHGDIDDQ--------FVSKRLIFDFNNSGSGQEFPIELSMGCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKSLVPNLV-DRLPPAVIHVDTKYFHTVC-CTASNEIFTWG 3624
            +P+ I+   ++ I Q+S G  H L L   G  ++ G N  GQLG+      Q S   + + L  I              +  +AAG  HS A+ +S +       VF WG    GQLG  D  D+          ++++++              +S G  H+ +LT  G V+ FG  S GQLG  ++   + P  V + +   V  +     HT+    +S  I+ +G
Sbjct:  127 VPRLIQKLNQQTILQVSCGNWHCLALAADGQFFTWGKNSHGQLGLGKEFPSQAS-PQRVRSLEGIP-------------LAQVAAGGAHSFALSLSGA-------VFGWGMNNAGQLGLSDEKDRESPCHVKLLRTQKVVY--------------ISCGEEHTAVLTKSGGVFTFGAGSCGQLGHDSMNDEVNPRRVLELMGSEVTQIACGRQHTLAFVPSSGLIYAFG 320          

Query: 3004 IRQISLGKNHALILTESGSLYSAGTNECGQLGIENHVLKQNSFV-NKNQCLSIIHPMLINIELNSDECIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHGDIDDQFVSKRLIFDFNNSGSGQEFPIELSMGCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKSLVPNLVDRLPPAVI-HVDTKYFHTVCCTASNEIFTWGIHPNIWQ--------NSLNHEKSHGEISIPESIYTGDLLSNQKIAQISCGTCHASILTDKQFVYCFGSNVWGQLGLGNRKDNKNLVEVNIPVPIDFVSSD 3900
            I+QI+ G +H L +T  G + S G N+ GQLG+ +    ++S V  K Q    I              I  +AAG  H+ A+       T++  ++ WGWG +G LG GD  D+ V +R+      + +G E    ++ G  H++ ++  G +Y +G + YGQLG   L+  L+P+ ++ L  + I  +   + HT+  T+  +++ WG     W         N+L+ + S  ++  P+         +QK+ Q+SCG  H   +T++  V+ +G    GQLG+G        V+ N P  I+ +S D
Sbjct:  122 IKQIACGDSHCLAVTMEGEVQSWGRNQNGQLGLGD---TEDSLVPQKIQAFEGIR-------------IKMVAAGAEHTAAV-------TEDGDLYGWGWGRYGNLGLGDRTDRLVPERV------TSTGGEKMSMVACGWRHTISVSYSGALYTYGWSKYGQLGHGDLEDHLIPHKLEALSNSFISQISGGWRHTMALTSDGKLYGWG-----WNKFGQVGVGNNLD-QCSPVQVRFPD---------DQKVVQVSCGWRHTLAVTERNNVFAWGRGTNGQLGIGES------VDRNFPKIIEALSVD 380          

Query: 2992 GKEIIRQISLGKNHALILTESG-SLYSAGTNECGQLGIENHVLKQNSFVNKNQCLSIIHPMLINIELNSDECIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHGDIDDQFVSKRLIFDFNNSGSGQEF-PIELSM---GCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKSLVPNLVDRLPPAVIH-VDTKYFHTVCCTASNEIFTWGIHPNIWQNSLNHEKSHGEIS---IPESIYTGDLLSNQKIAQISCGTCHASILTDKQFVYCFGSNVWGQLGLGNRKDNKNLVEVNIPVPIDFVSSDDGI--TIAMSKSENSTKLFVWGR 3963
            G +I+  ++ G +H +  ++SG  +YS G  + G+LG  N     +S +     +  +H + I            IA GD H  A+       T    V +WG   +GQLG GD +D  V +++          Q F  I + M   G  H+  +T  G +Y +G   YG LG+      LVP  V       +  V   + HT+  + S  ++T+G     W  S   +  HG++    IP  +   + LSN  I+QIS G  H   LT    +Y +G N +GQ+G+GN  D  + V+V  P     V    G   T+A+++  N   +F WGR
Sbjct:   66 GHQIV-SVTCGADHTVAYSQSGMEVYSWGWGDFGRLGHGN-----SSDLFTPLPIKALHGIRIK----------QIACGDSHCLAV-------TMEGEVQSWGRNQNGQLGLGDTEDSLVPQKI----------QAFEGIRIKMVAAGAEHTAAVTEDGDLYGWGWGRYGNLGLGDRTDRLVPERVTSTGGEKMSMVACGWRHTISVSYSGALYTYG-----W--SKYGQLGHGDLEDHLIPHKL---EALSNSFISQISGGWRHTMALTSDGKLYGWGWNKFGQVGVGNNLDQCSPVQVRFPDDQKVVQVSCGWRHTLAVTERNN---VFAWGR 354          

Query: 2941 IKEKSNRILLLPKSIES-GKEIIRQISLGKNHALILTESGSLYSAGTNECGQLG---IENHVLKQNSFVNKNQCLSIIHPMLINIELNSDECIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHGDIDDQFVSKRLIFDFNNSGSGQEFPIELSMGCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKSLVPNLVDRL 3543
            + ++++R  L+P+ + S G E +  ++ G  H + ++ SG+LY+ G ++ GQLG   +E+H++                     +E  S+  I  I+ G  H+ A+       T +  ++ WGW   GQ+G G+  DQ    ++ F  +      +  +++S G  H++ +T +  V+ +G  + GQLG+        P +++ L
Sbjct:  206 LGDRTDR--LVPERVTSTGGEKMSMVACGWRHTISVSYSGALYTYGWSKYGQLGHGDLEDHLIPH------------------KLEALSNSFISQISGGWRHTMAL-------TSDGKLYGWGWNKFGQVGVGNNLDQCSPVQVRFPDD------QKVVQVSCGWRHTLAVTERNNVFAWGRGTNGQLGIGESVDRNFPKIIEAL 377          

Query: 2998 EIIRQISL---GKNHALILTESGSLYSAGTNECGQLGIENHVLKQNSFVNKNQCLSIIHPMLINIELNSDECIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHGDIDDQFVSKRLIFDFNNSGSGQEFPIELSMGCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKSLVPNLVDRLPPAVIHVDTKYFHTVCCTA---SNEIFTWGIHPNIWQNSLNHEKSHGEISIPESIYTGDLLSNQKIAQISCGTCHASILTDKQFVYCFGSNVWGQLGLGNRKDNKNLVEVNIPVPIDFVSSDDGITIAMSKSENSTK-------LFVWGRC-GHSLIQEHI 3993
            ++IRQ  +     N  L  T +  ++  GTN CG LG+                 S I P  ++  LN  +    IA   Y SG  +V     T    VFTWG   + QLG+G  +   V   +  + +N     +  IE++ G +HS++LT+ G V+ +G N+ GQ+G  +     +P  V       + V T     +CC A   + E++ WG + N  Q  L +    G    P  +     L   ++ +++CG  H  +LTD+  VY +G+N +GQLG GN+ +       + P P+  V  D  I IA   S +++        +++WG+C G S+I  H+
Sbjct:   43 QLIRQACVFGSAGNEVLYTTVNDEIFVLGTNCCGCLGL-------------GDVQSTIEPRRLD-SLNGKK----IACLSYGSGPHIVLA---TTEGEVFTWGHNAYSQLGNGTTNHGLVPCHISTNLSN-----KQVIEVACGSYHSLVLTSDGEVFAWGYNNSGQVGSGSTVNQPIPRRVTGCLQNKV-VVTIACGQMCCMAVVDTGEVYVWGYNGN-GQLGLGNS---GNQPTPCRVAA---LQGIRVQRVACGYAHTLVLTDEGQVYAWGANSYGQLGTGNKSNQ------SYPTPVT-VEKDRIIEIAACHSTHTSAAKTQGGHVYMWGQCRGQSVILPHL 347          

Query: 2998 EIIRQISL---GKNHALILTESGSLYSAGTNECGQLGIENHVLKQNSFVNKNQCLSIIHPMLINIELNSDECIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHGDIDDQFVSKRLIFDFNNSGSGQEFPIELSMGCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKSLVPNLVDRLPPAVIHVDTKYFHTVCCTA---SNEIFTWGIHPNIWQNSLNHEKSHGEISIPESIYTGDLLSNQKIAQISCGTCHASILTDKQFVYCFGSNVWGQLGLGNRKDNKNLVEVNIPVPIDFVSSDDGITIAMSKSENSTK-------LFVWGRC-GHSLIQEHI 3993
            ++IRQ  +     N  L  T +  ++  GTN CG LG+                 S I P  ++  LN  +    IA   Y SG  +V     T    VFTWG   + QLG+G  +   V   +  + +N     +  IE++ G +HS++LT+ G V+ +G N+ GQ+G  +     +P  V       + V T     +CC A   + E++ WG + N  Q  L +    G    P  +     L   ++ +++CG  H  +LTD+  VY +G+N +GQLG GN+ +       + P P+  V  D  I IA   S +++        +++WG+C G S+I  H+
Sbjct:   43 QLIRQACVFGSAGNEVLYTTVNDEIFVLGTNCCGCLGL-------------GDVQSTIEPRRLD-SLNGKK----IACLSYGSGPHIVLA---TTEGEVFTWGHNAYSQLGNGTTNHGLVPCHISTNLSN-----KQVIEVACGSYHSLVLTSDGEVFAWGYNNSGQVGSGSTVNQPIPRRVTGCLQNKV-VVTIACGQMCCMAVVDTGEVYVWGYNGN-GQLGLGNS---GNQPTPCRVAA---LQGIRVQRVACGYAHTLVLTDEGQVYAWGANSYGQLGTGNKSNQ------SYPTPVT-VEKDRIIEIAACHSTHTSAAKTQGGHVYMWGQCRGQSVILPHL 347          

Query: 2965 LLLPKSIESGKEI---IRQISLGKNHALILTESGSLYSAGTNECGQLGIENHVLKQNSFVNKNQCLSIIHPMLINIELNSDECIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHGDIDDQFVSKRLIFDFNNSGSGQEFPI-ELSMGCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKSLVPNLVDRLPPAVIHVDTKYFHTVCCTASNEIFTWGIHPNIWQNSLNHEKSHGEISIP-----ESIYTGDLLS----NQKIAQISCGTCHASILTDKQFVYCFGSNVWGQLGLGNRKDNKNLVEVNIPVPI------DFVSSDDGITIAMSKSENSTKLFVWGR 3963
            + LP  +E+   +   +  +S G  H ++LT+ G +Y  G++  GQ+G+                 +   PML+   L+  E + ++  G YH+ A+       T    V++WGWGVHGQLG GD +DQ + K +  D+ N     EF + ++S G  HS+ LT KG VY  G   +GQLG+    K   P  + RLP  +I V T+YFH+V  TA+N +++WG HP   + S ++ +   +   P     ES     L+     N K++Q++CG+ H   LT    VY +G NV GQLG+G++      +E  IPV +      +F+S   G    M+  +N  +++VWGR
Sbjct:  818 ICLPSRVETLHMLQIKVTSVSCGGKHTIVLTQQG-VYGWGSSVYGQIGVGTR-------------HTYTRPMLLQTLLDIGESVIAVDCGQYHTLAL-------TDAGCVYSWGWGVHGQLGLGDPEDQLIPKNI--DYLN-----EFGVVKISAGYCHSLFLTAKGDVYSCGCAYFGQLGIGDNSKRTTPVKIIRLPEVIIAVSTRYFHSVAITANNRVYSWGCHPYSLRFSAHNMRRARQQGQPMLDPLESFLCPILIDTSFVNGKLSQVACGSFHTVALTTDGEVYVWGRNVDGQLGIGHK------IEERIPVMLTKLNDKEFLSVRCGGEYTMA-VDNDYQVWVWGR 1134          

Query: 3214 IAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHGDIDDQFVSKRLIFDFNNSGSGQEFPIE---LSMGCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKSLVPNLVDRL---PPAVIHVDTKYFHTVCCTASNEIFTWGIHPNIWQNSLNHEKSHGEIS--------IPESIYTGDLLSNQKIAQISCGTCHASILTDKQFVYCFGSNVWGQLGLGNRKDNKNLVE-VNIPVPIDFVSSDDGITIAMSKSENSTKLFVWGRCGHSL 3978
            I AG  H  +I        +N  ++TWG    G+LGHGD+    V K  I   +   +     I+   +S G  H+++LT +G VY +G++ YGQ+GV T      P L+  L     +VI VD   +HT+  T +  +++WG     W         HG++         IP++I   D L+   + +IS G CH+  LT K  VY  G   +GQLG+G+       V+ + +P  I  VS+    ++A++    + +++ WG   +SL
Sbjct:  781 IGAGPEHGASI--------RNGDLYTWGLTRDGRLGHGDL----VGKNSICLPSRVETLHMLQIKVTSVSCGGKHTIVLTQQG-VYGWGSSVYGQIGVGTRHTYTRPMLLQTLLDIGESVIAVDCGQYHTLALTDAGCVYSWG-----W-------GVHGQLGLGDPEDQLIPKNI---DYLNEFGVVKISAGYCHSLFLTAKGDVYSCGCAYFGQLGIGDNSKRTTPVKIIRLPEVIIAVSTRYFHSVAITA---NNRVYSWGCHPYSL 1019          

Query:  160 TGNLYFIQQSLEDGSIKVKKLIWITDSKISAFSINPTCDWIVIAYRNGMLCILPIGTLMGRIQKKSEYWKPNDVTYLLDKLKSGTFITCMKWWTSYKKKNMCIIGRSDGDLLIIDLENGMTLIEETFPDYIYSIDLLITKDKTLSYCFITTKIQSQWKLLLEEIHEKKDITDSDIGYEFMDFSSYHSHNIINXXXXXXXXXXXQRNPSYLPSKLYQFPQSTFLKSQYVNGKCFLGAYDQISGIYKLFECDNLDSSIYEFQLPLSVVDICVTEDLLYLI--IEQVKRRSESNNKNAIFTEPQ 1056
            + N   ++    + S ++K++ W  +  I +   +PT  W+++      + I+P   L+    + ++ W  ND T +     +G  +T + WW + +   + I G   G++++IDL     +   +    +  +DL+    +  +   IT    +QWKLLLE        + S   +  M+ +S                   +    + P K  QF +S  L  Q   G+ F+ A+   +  +++F+     S  + ++LP    ++  T+ L++ I  I   +    SN K  I +E Q
Sbjct:   52 SNNYLLLRHKTANKSPEIKQIPWPAEKTIISMCFDPTVVWLLVITDTPDIYIIPALCLLEPKSRVNQLWATNDATQITLNKPTG-MVTKVCWWHTLEDDQIAIYGTKAGEIVLIDLLRRRMVACTSIHGQVIDLDLIQDDQQMTTVLLITGNSGNQWKLLLE--------SRSQQNWRPMNETSLLGSERRLPSITNIMMNSDELKGMFTPVKFTQFDRSVILYPQNAKGRHFVTAHCDKTSTFQVFDSHLEHSPFFIYKLPFGTYNVIFTDCLMFAISSIHGQRLLVLSNQKAEISSEDQ 343          

Query: 3004 IRQISLGKNHALILTESGSLYSAGTNECGQLGI-ENHVLKQNSFVNKNQCLSIIHPMLINIELNSDECIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHGDIDDQFVSKRLIFDFNNSGSGQEFPIELSMGCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKSLVPNLVDRLPPAVIHVDTKYFHTVCCTASNEIFTWGIHP-NIWQ--NSLNHEKSHGE----------ISIPESIYTGDLLSNQKIAQISCGTCHASILTDKQFVYCFGSNVWGQLGLGNRKDNKNLVEVNIPVPIDFVSSDDGITIAMSKSENSTKLF-------VWGR 3963
            +  ++ G  H L LT+ G +Y  G ++ GQ+G+  +H+ K+              PML+   L SD  + +I  G YHS A+       T +  ++TWGWGVHGQLGHG+ +D  + K + +  N +       ++++ G  HS++LT  G V+ FG   +GQLG+    K+  P  V  LP AV  + TK+FH +  T +N+I+TWG+HP N+ Q  +S+   +  G            S+ +S Y      + +I ++ CG+ H+ +LT+   VY +G N+ GQLG G+R+D +        +P    S +D   +A++     T  F        WG+
Sbjct:  149 VDAVACGCEHTLALTQQG-VYGWGNSKYGQVGVGTSHIYKR--------------PMLLET-LQSDT-VVAIDCGQYHSLAL-------TADHQIYTWGWGVHGQLGHGNPEDCLIPKHVTYLLNLA------VVQIAGGYAHSLVLTESGDVWSFGCGYFGQLGLGMNNKTTYPQKV-LLPTAVTAIGTKFFHCIAVTVTNKIYTWGLHPQNLRQIASSIRSARLAGSNDQDQNAFMFPSLVDSTYV-----HGQITKVCCGSLHSVLLTEDGSVYLWGRNLEGQLGTGSRQDER--------IPKMVTSINDQQIVAIASGGEFTLAFSSDGCIWAWGK 445          

Query: 3214 IAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHGDIDDQFVSKRLIFDFNNSGSGQEFPIE-LSMGCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKSLVPNLVDRL-PPAVIHVDTKYFHTVCCTASNEIFTWGIHPNIWQNSLNHEKSHG---EISIPESIYTGDLLSNQKIAQISCGTCHASILTDKQFVYCFGSNVWGQLGLGNRKDNKNLVEVNIPVPIDFVSSDDGITIAMSKSENSTKLFVWG 3960
            IA G  H   I        +N  V+T G    G+LG GDI         + + +      +  ++ ++ GC H++ LT +G VY +GN+ YGQ+GV T      P L++ L    V+ +D   +H++  TA ++I+TWG     W   ++ +  HG   +  IP+ +     L N  + QI+ G  H+ +LT+   V+ FG   +GQLGLG         +V +P  +  + +     IA++ +    K++ WG
Sbjct:   98 IACGPKHCAVI--------RNGDVYTCGKSQGGRLGVGDIPQNACPPVRVENLHT----LQLKVDAVACGCEHTLALTQQG-VYGWGNSKYGQVGVGTSHIYKRPMLLETLQSDTVVAIDCGQYHSLALTADHQIYTWG-----W--GVHGQLGHGNPEDCLIPKHV---TYLLNLAVVQIAGGYAHSLVLTESGDVWSFGCGYFGQLGLGMNNKTTYPQKVLLPTAVTAIGTKFFHCIAVTVTN---KIYTWG 325          

Query: 2995 KEIIRQISLGKNHALILTESGSLYSAGTNECGQLGIENHVLKQNSFVNKNQCLSIIHPMLINIELNSDECIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHGDIDDQFVSKRLIFDFNNSGSGQEFPIELSMGCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKSLVPNLVDRLPPAVIHVDTKYFHTVCCTASNEIFTWGIHPNIW-------QNSLNHEKSHG---EISIPESIYTGDLLSNQKIAQISCGTCHASILTDKQFVYCFGSNVWGQLGLGNRKDNKNLVEVNI--PVPIDFVSSDDGITIAMSKSENSTKLFVWGR 3963
            K  +  ++ G  H L L+  G +YS G+++ GQ+G+  +    + +  +        PML+  E  S EC  S+  G YHS A+       T +  VFTWGWGVHGQLGHGD ++Q V K LI     +   +   I+L+ G  H+++L+ +G VY FG   +GQLG+   QK  VP+ +  LP  + ++   +F +V  T  + ++ WGIHPNI        + +   E + G   +   P  + T ++L   KI Q+SCG+ H  +LT    VY +G N  GQLG  + ++     +V     V I  V S     +A++   +  +++ WGR
Sbjct:  833 KICVTSVTCGGEHILALSSQG-VYSWGSSKYGQVGVGAY----HHYYTR--------PMLV--ESLSSECCVSLVCGQYHSVAL-------TNDGKVFTWGWGVHGQLGHGDAENQSVPK-LISCLPTAKEIRT--IQLAAGYAHTMVLSQQGDVYSFGCGYFGQLGLGQRQKKSVPSHIT-LPEKISYIAANFFSSVAVTQDSSVYCWGIHPNIIRYAAQMSRRAPGQEAADGFGDDYLSPLLVDTSNVLG--KIVQVSCGSYHFVLLTSDGVVYTWGRNTDGQLGFVSYQNISFPTQVTAISDVHISHVYSGSDFNVALN---SDGEVWGWGR 1136          

Query:  106 FSDNFALLCIYQSSSSS------DTGNLYFIQQSLEDGSIKVKKLIWITDSKISAFSINPTCDWIVIAYRNGMLCILPIGTLMGRIQKKSEYWKPNDVTYLLDKLKSGTFITCMKWWTSYKKKNMCIIGRSDGDLLIIDLENGMTLIEETFPDYIYSIDLLITKDKTLSYCFITTKIQSQWKLLLEEIHEKKDITDSDIGYEFMDFSSYHSHNIINXXXXXXXXXXXQRNPSYLPSKLYQFPQSTFLKSQYVNGKCFLGAYDQISGIYKLFECDNLDSSIYEFQLPLSVVDICVTEDLLYL 990
            F  N A     Q+  +S        G+L  I  S+     K + L W+    I +   +P+  W+++      + I+P  +LM    K    WK +D T++  K   G F + + WW +    ++ I+G S G+L+ ++L     L   +   YI  +DL+   ++   +  +T+K  SQW+LLLE+++  +   + ++  +    S+  +++ + S   + +  +    P Y P    QF +S  L  QY  G+  + A+   +  Y++++C    S +Y ++LPL   +   T+ L++L
Sbjct:   23 FQPNIAQFAWRQARDTSLLALVCSNGHL-LIYWSVPGQRPKSRLLPWLEQRPIVSLCFDPSATWLLVITTQIDMFIIPALSLMDPQSKVDATWKRDDATHIRFKKPKG-FPSALCWWHTLTGYDVAIVGTSLGELVFVNLHTKRVLANTSIQSYIVKLDLIFDDEQVSRHLLVTSKKGSQWQLLLEKLNRSEWYQEIELVSKSSLLSADDTYSNVVSIIDRAAGYQDLFWPVYFP----QFGRSIQLSPQYAKGRQLVAAHCCRTCSYQIYDCSIQRSPLYIYKLPLGAHNTVFTDRLIFL 317          

Query: 3271 QNSHVFTWGWGVHGQLGHGDIDDQFVSKRLIFDFNNSGSGQEFPI---ELSMGCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKSLV-PNLVDRLPP-AVIHVDTKYFHTVCCTASNEIFTWGIHPNIWQNSLNHEKSHGEI---SIPESIYTGDLLSNQKIAQISCGTCHASILTDKQFVYCFGSNVWGQLGLGNRKDNKNLVEVNIPVPIDFVSSDDGITIAMSKSENSTKLFVWG 3960
            +N  ++TWG    G LGHGD+     S+  +   +   +     I    ++ G  H + L+++G VY +G++ YGQ+GV         P LV+ L     + +    +H+V  T   ++FTWG     W   ++ +  HG+    S+P+ I         +  Q++ G  H  +L+ +  VY FG   +GQLGLG R+       + +P  I +++++   ++A+++    + ++ WG
Sbjct:  794 RNGDLYTWGKSNSGCLGHGDL----TSEDTVMPVSRVETLHMLKICVTSVTCGGEHILALSSQG-VYSWGSSKYGQVGVGAYHHYYTRPMLVESLSSECCVSLVCGQYHSVALTNDGKVFTWG-----W--GVHGQLGHGDAENQSVPKLISCLPTAKEIRTIQLAAGYAHTMVLSQQGDVYSFGCGYFGQLGLGQRQKKSVPSHITLPEKISYIAANFFSSVAVTQ---DSSVYCWG 1016          

Query: 3004 IRQISLGKNHALILTESGSLYSAGTNECGQLGI-ENHVLKQNSFVNKNQCLSIIHPMLI-NIELNSDECIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHGDIDDQFVSKRLIFDFNNSGSGQEFPIELSMGCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKSLVPNLVD-RLPPAVIHVDTKYFHTVCCTASNEIFTWGIHP-NIWQ--NSLNHEKSHG----------EISIPESIYTGDLLSNQKIAQISCGTCHASILTDKQFVYCFGSNVWGQLGLGNRKDNKNLVEVNIPVPIDFVSSDDGITIAMSKSENST-----KLFVWGR 3963
            +  ++ G  H L LT+ G +Y  G +  GQ+G+   HV ++              PML+  ++L   E + S+  G YHS A+       T++  V++WGWGVHGQLGHGD +D  + + + +  N         ++++ G  HS+ LT  G V+ FG   +GQLG+ T  K+ +P  +       +I + T YFH +  +A+N +F WG+HP N+ Q  +S+   +  G          + S+ ++ Y      + KI ++ CG+ H  +L D   +Y +G N+ GQLG G+R+D +      IP  +  ++    +++A     N +      ++VWG+
Sbjct:  862 VEAVACGCEHTLALTQQG-VYGWGNSRYGQVGVGTRHVYRR--------------PMLVEGLQL---EVVVSVQCGHYHSLAL-------TEDHQVYSWGWGVHGQLGHGDPEDCLIPQHVRYLMNTG------VVKVAAGYAHSLALTESGQVWSFGCGYFGQLGLGTNSKTSIPERISFPTTSPMIAIGTNYFHGLAVSATNRVFQWGLHPHNLRQVASSMRMARHAGVHVSEQNHFLQPSLVDTTYV-----HGKITKLCCGSLHNVLLADDGVIYIWGRNLEGQLGTGSRQDER------IPKMLTCINDQQIVSVASGGEFNVSFDSEGGIWVWGK 1160          

Query: 3214 IAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHGDIDDQFVSKRLIFDFNNSGSGQEFPIE-LSMGCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKSLVPNLVDRLP-PAVIHVDTKYFHTVCCTASNEIFTWGIHPNIWQNSLNHEKSHGEIS---IPESIYTGDLLSNQKIAQISCGTCHASILTDKQFVYCFGSNVWGQLGLGNRKDNKNLVEVNIPVPIDFVSSDDGITIAMS-----KSENSTKLFVWGRCGHSLIQ 3984
            +A G  H+ AI        +N  ++TWG  + G+LGHGD+     +   +   +      +  +E ++ GC H++ LT +G VY +GN+ YGQ+GV T      P LV+ L    V+ V   ++H++  T  +++++WG     W   ++ +  HG+     IP+ +     L N  + +++ G  H+  LT+   V+ FG   +GQLGLG         + +IP  I F ++   I I  +         + ++F WG   H+L Q
Sbjct:  811 VACGPKHAAAI--------RNGDLYTWGRSLQGRLGHGDVPQAVCTPTRVETLHM----LKLRVEAVACGCEHTLALTQQG-VYGWGNSRYGQVGVGTRHVYRRPMLVEGLQLEVVVSVQCGHYHSLALTEDHQVYSWG-----W--GVHGQLGHGDPEDCLIPQHVR---YLMNTGVVKVAAGYAHSLALTESGQVWSFGCGYFGQLGLGTNS------KTSIPERISFPTTSPMIAIGTNYFHGLAVSATNRVFQWGLHPHNLRQ 1048          

Query:  211 VKKLIWITDSKISAFSINPTCDWIVIAYRNG-MLCILPIGTLMGRIQKKSEYWKPNDVTYLLDKLKSGTFITCMKWWTSYKKKNMCIIGRSDGDLLIIDLENGMTLIEETFPDYIYSIDLLITKDKTLSYCFITTKIQSQWKLLLEEIHEKK----DITDSDIGYEFMDFSSYHSHNIINXXXXXXXXXXXQRNPS-YLPSKLYQFPQSTFLKSQYVNGKCFLGAYDQISGIYKLFECDNLDSSIYEFQLPLSVVDICVTEDLLYLIIEQVKRR 1014
            +K++ W+ D +I++   +PT  W++I   +   + ILP  +++      ++ +K  DVT    K+ SG  +TC  WW +   + + IIG   G++L+IDLE      + T    I  I L     +  +   ITT   +QW++LLE          D+  +++GY+ +D  S    +I++         + + N S + PS+   F   T L  QY  G+ F+ A+  +S   ++ + D   S ++ ++LP    ++ +T+ L++ ++   + R
Sbjct:   65 IKQVSWLPDKRIASMCFDPTLTWLLIVTESSNEIYILPALSIVNPNAVVNQIFKTEDVTVRSFKMTSG-HVTCAVWWQTLDGRQVAIIGTKVGEILLIDLEKEEEPRKVTIDVTITDISLSQDDQQINTTLLITTVTGNQWRMLLESRTSASTFFPDLYLNEMGYDNIDGRSIPPRSILD---------ETEENSSLFSPSQFANFQPPTVLWPQYARGRHFITAHCTVSSTLQVLDSDAEHSPLFVYKLPGGARNVILTDKLIFTMLSDSRER 328          

Query: 3013 ISLGKNHALILTESGSLYSAGTNECGQLGI-ENHVLKQNSFVNKNQCLSIIHPMLINIELNSDECIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHGDIDDQFVSKRLIFDFNNSGSGQEFPIELSMGCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKSLVPNLVDRLPPAVIHVDTKYFHTVCCTASNEIFTWGIHP---NIWQNSLNHEKSHGEIS--------IPESIYTGDLLSNQKIAQISCGTCHASILTDKQFVYCFGSNVWGQLGLGNRKDNK 3849
            ++ G  H L LT+ G +++ G+++ GQ+GI   H+  +              PM +N +L+S +C+ S+  G YHS A+ V       +  V++WGWGVHGQLGHG I+D  V   +      + S ++  I +  G  H+V L+++G VY FG   +GQLG+ T +K  +P  +  L   V+ V TK+FH +  T SN +F+WG HP       +S+   +  G +         +P+ + T     + +I Q  CG+ H++++T    VY +G N+ GQ+G   R+D K
Sbjct:  850 VACGGEHTLALTQQG-VFAWGSSQYGQVGIGTRHIYSR--------------PMQVN-KLSSVQCV-SVETGQYHSLALTV-------DGEVYSWGWGVHGQLGHGSIEDALVPSHV-----QALSDKQI-IRVCGGYCHTVALSSEGEVYSFGCGFFGQLGLATNKKQTLPVRIHALKGKVVLVSTKFFHNIAVTQSNHVFSWGCHPFNLRFAAHSIRKARQAGAVVGDPVDHFLLPDLVDT--CFVHGRITQAVCGSSHSALVTLDGDVYTWGRNMDGQIGNNTRQDMK 1108          

Query:  217 KLIWITDSKISAFSINPTCDWIVIAYRNGMLCILPIGTLMGRIQKKSEYWKPNDVTYLLDKLKSGTFITCMKWWTSYKKKNMCIIGRSDGDLLIIDLENGMTLIEETFPDYIYSIDLLITKDKTLSYCFITTKIQSQWKLLLE-EIHEKKDITDS---DIGYEFMDFSSYHSHNIINXXXXXXXXXXXQRNPSYLPSKLYQFPQSTFLKSQYVNGKCFLGAYDQISGIYKLFECDNLDSSIYEFQLPLSVVDICVTEDLLY 987
            +L W  D  IS+   +PT  W+++   +  L I+P   +M    K ++ W+ +DVT    K   G   T + WW +   + + IIG   G+++ +DL    TL +      I  ID++    +  +   IT +   QWKLLLE   HE   + D    D+GY  +D          N      +    Q    +LP + YQF +S FL  QY  G+ F+ A+   +  Y++++ D   + ++ ++LP    ++ +T+ +++
Sbjct:   64 QLPWPQDKPISSMCFDPTVTWLLVLAEDATLFIIPALPIMDPTAKVNQLWREDDVTITKVKRPKGV-PTALLWWHTLDDRQIAIIGTKIGEIIFVDLVTRKTLYDINCDCKIMQIDIVEDDQQMTTNLLITDQSGVQWKLLLESRTHEILSLPDKELLDLGYNTVDGR--------NLPIISITTPSDQTRDLFLPLRFYQFQRSVFLSPQYAKGRHFVAAHCDKTNTYQIYDSDVEHNPLFVYKLPFGAYNVILTDKVIF 315          

Query: 3271 QNSHVFTWGWGVHGQLGHGDI-DDQFVSKRLIFDFNNSGSGQEFPIELSMGCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKSLVPNLVDRLPPA-VIHVDTKYFHTVCCTASNEIFTWGIHPNIWQNSLNHEKSHGEIS---IPESIYTGDLLSNQKIAQISCGTCHASILTDKQFVYCFGSNVWGQLGLGNRKDNKNLVEVN-IPVPIDFVSSDDGITIAMSKSENSTKLFVWG 3960
            +N  ++TWG   HG+LGHGD+  D  VS     +  +    Q   I ++ G  H++ LT +G V+ +G++ YGQ+G+ T      P  V++L     + V+T  +H++  T   E+++WG     W   ++ +  HG I    +P  +     LS+++I ++  G CH   L+ +  VY FG   +GQLGL   K     V ++ +   +  VS+     IA+++S +   +F WG
Sbjct:  805 RNGDLYTWGRTSHGRLGHGDLAPDNTVSPPCRVETLH--MLQVRVISVACGGEHTLALTQQG-VFAWGSSQYGQVGIGTRHIYSRPMQVNKLSSVQCVSVETGQYHSLALTVDGEVYSWG-----W--GVHGQLGHGSIEDALVPSHVQA---LSDKQIIRVCGGYCHTVALSSEGEVYSFGCGFFGQLGLATNKKQTLPVRIHALKGKVVLVSTKFFHNIAVTQSNH---VFSWG 1024          

Query: 3004 IRQISLGKNHALILTESGSLYSAGTNECGQLGIENHVLKQNSFVNKNQCLSIIHPMLINIELNSDECIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHGDIDDQFVSKRLI---------------------------FDFNNSGSGQ--------------------EFPI-ELSMGCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKSLVPNLVDRL-PPAVIHVDTKYFHTVCCTASNEIFTWGIHPNIWQNSLNHEKSHGEISIPESIYTGDLLSNQKIAQISCGTCHA-SILTDKQFVYCFGSNVWGQLGLGNRKDNKNLVEVNIPVPI 3882
            +++++    H+L L   GS+YS G+N  GQLG E    K               P L+ + L++ + I  +A GD HS A+        +   VF WG G  GQLG G +++     RLI                           F +  + SGQ                      P+ ++S G  HS  L+  G V+ +G NS GQLG+   Q   VP  +  L    V+++     HT   T    +FT+G   N  +  L H+ ++ E  +P  +     L   +++QI CG  H  + +     VY FG N  GQLGL NR + +      IP+P+
Sbjct:   35 LKEVACRGQHSLFLLHDGSVYSCGSNSHGQLGHEKPGNK---------------PELV-VALDAQK-IAGVACGDAHSLAV-------NEQGQVFAWGTGEKGQLGLGTVEEAVRVPRLIKKLCEHRISQVMCGNQHCIALAKDGQLFTWGQNSSGQLGLGKGEPSSLSPQPLKSLCGIPLAQISAGGDHSFALSLSGAVFGWGRNSAGQLGLNDEQDRAVPCHIKFLRSQKVVYISCGDEHTAALTKDGGLFTFG---NGSRGQLGHDSTNNE-PLPRRVLE---LMGTEVSQIVCGKHHTLAFVPSTGLVYAFGCNAHGQLGLANRGNAR------IPLPV 340          

Query: 3004 IRQISLGKNHALILTESGSLYSAGTNECGQLGIENHVLKQNSFVNKNQCLSIIHPMLINIELNSDECIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHGDIDDQFVSKRLIFDFNNSGSGQEFPIELSMGCFHSV-ILTNKGFVYCFGNNSYGQLGVQTLQKSLVPNLVDRLPPAVI 3558
            + QIS G +H+  L+ SG+++  G N  GQLG+ +   +Q+  V          P  I   L S + ++ I+ GD H+ A+       T++  +FT+G G  GQLGH   +++ + +R++       S      ++  G  H++  + + G VY FG N++GQLG+     + +P  V  + P  +
Sbjct:  191 LAQISAGGDHSFALSLSGAVFGWGRNSAGQLGLND---EQDRAV----------PCHIKF-LRSQKVVY-ISCGDEHTAAL-------TKDGGLFTFGNGSRGQLGHDSTNNEPLPRRVLELMGTEVS------QIVCGKHHTLAFVPSTGLVYAFGCNAHGQLGLANRGNARIPLPVRNIQPPYL 348          

Query: 3283 VFTWGWGVHGQLGHGDIDDQFVSKRLIFDFNNSGSGQEFPIELSMGCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKSLVPNLVDRLPPAVIH-VDTKYFHTVCCTASNEIFTWGIHPNIWQNSLNHEKSHGEISIPESIYTGDLLSNQKIAQISCGTCHASILTDKQFVYCFGSNVWGQLGLGNRKD---NKNLVEVNIPVPIDFVSSDDGITIAMSKSENSTKLFVWGR 3963
            +  WG    GQLG GD +      R    F  SG G +   E++    HS+ L + G VY  G+NS+GQLG +  +    P LV  L    I  V     H++      ++F WG      +  L        + +P  I     L   +I+Q+ CG  H   L     ++ +G N  GQLGLG  +    +   ++    +P+  +S+    + A+S    S  +F WGR
Sbjct:    1 MLCWGSSAWGQLGLGDAEPVVAEPRSCRMF--SGRGLK---EVACRGQHSLFLLHDGSVYSCGSNSHGQLGHE--KPGNKPELVVALDAQKIAGVACGDAHSLAVNEQGQVFAWGTGE---KGQLGLGTVEEAVRVPRLIKK---LCEHRISQVMCGNQHCIALAKDGQLFTWGQNSSGQLGLGKGEPSSLSPQPLKSLCGIPLAQISAGGDHSFALSL---SGAVFGWGR 215          

Query: 3271 QNSHVFTWGWGVHGQLGHGDIDDQFVSKRLIFDFNNSGSGQEFPIELSMGCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKSL-VPNLVDRLPPAVI-HVDTKYFHTVCCTASNEIFTWGIHPNIWQNSLNHEKSHGEISI----PESIYTGDL--LSNQKIAQISCGTCHASILTDKQFVYCFGSNVWGQLGLGNRKDNKNLVEVNIPVPIDFVSSDDGITIAMSKSENST-----KLFVWG 3960
             +  V++ G   HGQLGH    ++     L+   +     Q+    ++ G  HS+ +  +G V+ +G    GQLG+ T+++++ VP L+ +L    I  V     H +      ++FTWG            + S G++ +    P S+    L  L    +AQIS G  H+  L+    V+ +G N  GQLGL + +D        +P  I F+ S   + I+      +       LF +G
Sbjct:   50 HDGSVYSCGSNSHGQLGHEKPGNK---PELVVALD----AQKI-AGVACGDAHSLAVNEQGQVFAWGTGEKGQLGLGTVEEAVRVPRLIKKLCEHRISQVMCGNQHCIALAKDGQLFTWG------------QNSSGQLGLGKGEPSSLSPQPLKSLCGIPLAQISAGGDHSFALSLSGAVFGWGRNSAGQLGLNDEQDRA------VPCHIKFLRSQKVVYISCGDEHTAALTKDGGLFTFG 266          

Query: 2974 PKSIE--SGKEIIRQISLGKNHALILTESGSLYSAGTNECGQLGIENHVLKQNSFVNKNQCLSIIHPMLINIELNSDECIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHGDIDDQFVSKRLI---------------------------FDFNNSGSGQ--------------------EFPI-ELSMGCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKSLVPNLVDRL-PPAVIHVDTKYFHTVCCTASNEIFTWGIHPNIWQNSLNHEKSHGEISIPESIYTGDLLSNQKIAQISCGTCHA-SILTDKQFVYCFGSNVWGQLGLGNRKDNKNLVEVNIPVPI 3882
            P+S    SG+ + ++++    H+L L   GS+YS G+N  GQLG E    K               P L+ + L++ + I  +A GD HS A+        +   VF WG G  GQLG G +++     RLI                           F +  + SGQ                      P+ ++S G  HS  L+  G V+ +G NS GQLG+   Q   VP  +  L    V+++     HT   T    +FT+G   N  +  L H+ ++ E  +P  +     L   +++QI CG  H  + +     VY FG N  GQLGL NR + +      IP+P+
Sbjct:   24 PRSCRMFSGRGL-KEVACRGQHSLFLLHDGSVYSCGSNSHGQLGHEKPGNK---------------PELV-VALDAQK-IAGVACGDAHSLAV-------NEQGQVFAWGTGEKGQLGLGTVEEAVRVPRLIKKLCEHRISQVMCGNQHCIALAKDGQLFTWGQNSSGQLGLGKGEPSSLSPQPLKSLCGIPLAQISAGGDHSFALSLSGAVFGWGRNSAGQLGLNDEQDRAVPCHIKFLRSQKVVYISCGDEHTAALTKDGGLFTFG---NGSRGQLGHDSTNNE-PLPRRVLE---LMGTEVSQIVCGKHHTLAFVPSTGLVYAFGCNAHGQLGLANRGNAR------IPLPV 340          

Query: 3283 VFTWGWGVHGQLGHGDIDDQFVSKRLIFDFNNSGSGQEFPIELSMGCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKSLVPNLVDRLPP-AVIHVDTKYFHTVCCTASNEIFTWGIHPNIWQNSLNHEKSHGEISIPESIYTGDLLSNQKIAQISCGTCHASILTDKQFVYCFGSNVWGQLGLGNRKD---NKNLVEVNIPVPIDFVSSDDGITIAMSKSENSTKLFVWGR 3963
            +  WG    GQLG GD +      R    F  SG G +   E++    HS+ L + G VY  G+NS+GQLG +  +    P LV  L    +  V     H++      ++F WG      +  L        + +P  I     L   +I+Q+ CG  H   L     ++ +G N  GQLGLG  +    +   ++    +P+  +S+    + A+S    S  +F WGR
Sbjct:    1 MLCWGSSAWGQLGLGDAEPVVAEPRSCRMF--SGRGLK---EVACRGQHSLFLLHDGSVYSCGSNSHGQLGHE--KPGNKPELVVALDAQKIAGVACGDAHSLAVNEQGQVFAWGTGE---KGQLGLGTVEEAVRVPRLIKK---LCEHRISQVMCGNQHCIALAKDGQLFTWGQNSSGQLGLGKGEPSSLSPQPLKSLCGIPLAQISAGGDHSFALSL---SGAVFGWGR 215          

Query: 3271 QNSHVFTWGWGVHGQLGHGDIDDQFVSKRLIFDFNNSGSGQEFPIELSMGCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKSL-VPNLVDRLPPAVI-HVDTKYFHTVCCTASNEIFTWGIHPNIWQNSLNHEKSHGEISI----PESIYTGDL--LSNQKIAQISCGTCHASILTDKQFVYCFGSNVWGQLGLGNRKDNKNLVEVNIPVPIDFVSSDDGITIAMSKSENST-----KLFVWG 3960
             +  V++ G   HGQLGH    ++     L+   +     Q+    ++ G  HS+ +  +G V+ +G    GQLG+ T+++++ VP L+ +L    I  V     H +      ++FTWG            + S G++ +    P S+    L  L    +AQIS G  H+  L+    V+ +G N  GQLGL + +D        +P  I F+ S   + I+      +       LF +G
Sbjct:   50 HDGSVYSCGSNSHGQLGHEKPGNK---PELVVALD----AQKI-AGVACGDAHSLAVNEQGQVFAWGTGEKGQLGLGTVEEAVRVPRLIKKLCEHRISQVMCGNQHCIALAKDGQLFTWG------------QNSSGQLGLGKGEPSSLSPQPLKSLCGIPLAQISAGGDHSFALSLSGAVFGWGRNSAGQLGLNDEQDRA------VPCHIKFLRSQKVVYISCGDEHTAALTKDGGLFTFG 266          

Query: 2974 PKSIE--SGKEIIRQISLGKNHALILTESGSLYSAGTNECGQLGIENHVLKQNSFVNKNQCLSIIHPMLINIELNSDECIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHGDIDDQFVSKRLI---------------------------FDFNNSGSGQ--------------------EFPI-ELSMGCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKSLVPNLVDRL-PPAVIHVDTKYFHTVCCTASNEIFTWGIHPNIWQNSLNHEKSHGEISIPESIYTGDLLSNQKIAQISCGTCHA-SILTDKQFVYCFGSNVWGQLGLGNRKDNKNLVEVNIPVPI 3882
            P+S    SG+ + ++++    H+L L   GS+YS G+N  GQLG E    K               P L+ + L++ + I  +A GD HS A+        +   VF WG G  GQLG G +++     RLI                           F +  + SGQ                      P+ ++S G  HS  L+  G V+ +G NS GQLG+   Q   VP  +  L    V+++     HT   T    +FT+G   N  +  L H+ ++ E  +P  +     L   +++QI CG  H  + +     VY FG N  GQLGL NR + +      IP+P+
Sbjct:   24 PRSCRMFSGRGL-KEVACRGQHSLFLLHDGSVYSCGSNSHGQLGHEKPGNK---------------PELV-VALDAQK-IAGVACGDAHSLAV-------NEQGQVFAWGTGEKGQLGLGTVEEAVRVPRLIKKLCEHRISQVMCGNQHCIALAKDGQLFTWGQNSSGQLGLGKGEPSSLSPQPLKSLCGIPLAQISAGGDHSFALSLSGAVFGWGRNSAGQLGLNDEQDRAVPCHIKFLRSQKVVYISCGDEHTAALTKDGGLFTFG---NGSRGQLGHDSTNNE-PLPRRVLE---LMGTEVSQIVCGKHHTLAFVPSTGLVYAFGCNAHGQLGLANRGNAR------IPLPV 340          

Query: 3004 IRQISLGKNHALILTESGSLYSAGTNECGQLGIENHVLKQNSFVNKNQCLSIIHPMLINIELNSDECIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHGDIDDQFVSKRLIFDFNNSGSGQEFPIELSMGCFHSV-ILTNKGFVYCFGNNSYGQLGVQTLQKSLVPNLVDRLPPAVIHVDTKYFHTV 3588
            + QIS G +H+  L+ SG+++  G N  GQLG+ +   +Q+  V          P  I   L S + ++ I+ GD H+ A+       T++  +FT+G G  GQLGH   +++ + +R++       S      ++  G  H++  + + G VY FG N++GQLG+     + +P  V  + P  +       H V
Sbjct:  191 LAQISAGGDHSFALSLSGAVFGWGRNSAGQLGLND---EQDRAV----------PCHIKF-LRSQKVVY-ISCGDEHTAAL-------TKDGGLFTFGNGSRGQLGHDSTNNEPLPRRVLELMGTEVS------QIVCGKHHTLAFVPSTGLVYAFGCNAHGQLGLANRGNARIPLPVRNIQPPYLSSSQTSGHDV 358          

Query: 3283 VFTWGWGVHGQLGHGDIDDQFVSKRLIFDFNNSGSGQEFPIELSMGCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKSLVPNLVDRL-PPAVIHVDTKYFHTVCCTASNEIFTWGIHPNIWQNSLNHEKSHGEISIPESIYTGDLLSNQKIAQISCGTCHASILTDKQFVYCFGSNVWGQLGLGNRKD---NKNLVEVNIPVPIDFVSSDDGITIAMSKSENSTKLFVWGR 3963
            +  WG    GQLG GD +      R    F  SG G +   E++    HS+ L + G VY  G+NS+GQLG +  +    P LV  L    +  V     H++      ++F WG      +  L        + +P  I     L   +I+Q+ CG  H   L     ++ +G N  GQLGLG  +    +   ++    +P+  +S+    + A+S    S  +F WGR
Sbjct:    1 MLCWGSSAWGQLGLGDAEPVVAEPRSCRMF--SGRGLK---EVACRGQHSLFLLHDGSVYSCGSNSHGQLGHE--KPGNKPELVVALDAQKIAGVACGDAHSLAVNEQGQVFAWGTGE---KGQLGLGTVEEAVRVPRLIKK---LCEHRISQVMCGNQHCIALAKDGQLFTWGQNSSGQLGLGKGEPSSLSPQPLKSLCGIPLAQISAGGDHSFALSL---SGAVFGWGR 215          

Query: 3271 QNSHVFTWGWGVHGQLGHGDIDDQFVSKRLIFDFNNSGSGQEFPIELSMGCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKSL-VPNLVDRLPPAVI-HVDTKYFHTVCCTASNEIFTWGIHPNIWQNSLNHEKSHGEISI----PESIYTGDL--LSNQKIAQISCGTCHASILTDKQFVYCFGSNVWGQLGLGNRKDNKNLVEVNIPVPIDFVSSDDGITIAMSKSENST-----KLFVWG 3960
             +  V++ G   HGQLGH    ++     L+   +     Q+    ++ G  HS+ +  +G V+ +G    GQLG+ T+++++ VP L+ +L    I  V     H +      ++FTWG            + S G++ +    P S+    L  L    +AQIS G  H+  L+    V+ +G N  GQLGL + +D        +P  I F+ S   + I+      +       LF +G
Sbjct:   50 HDGSVYSCGSNSHGQLGHEKPGNK---PELVVALD----AQKI-AGVACGDAHSLAVNEQGQVFAWGTGEKGQLGLGTVEEAVRVPRLIKKLCEHRISQVMCGNQHCIALAKDGQLFTWG------------QNSSGQLGLGKGEPSSLSPQPLKSLCGIPLAQISAGGDHSFALSLSGAVFGWGRNSAGQLGLNDEQDRA------VPCHIKFLRSQKVVYISCGDEHTAALTKDGGLFTFG 266          

Query: 2998 EIIRQISLGKNHALILTESGSLYSAGTNECGQLGIENHVLKQNSFVNKNQCLSIIHPMLINIELNSDECIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHGDIDDQFVSKRLIFDFNNSGSGQEFPIELSMGCFHSVILTNKGFVYCFGNNSYGQLGVQT--LQKSLVPNLVDRLPPAVIHVDTKYFHTVCCTASNEIFTWGIHPNIWQNSLNHEKSHGEISIPESIYTGDLLSNQKIAQISCGTCHASILTDKQFVYCFGSNVWGQLGLGN 3834
            E +R  + G NH L+ T  G +++AG N  GQLG+  H  ++ SF         +HP      L        ++AG   S A+       T++  +F WG    GQLG G  +     K L  D + +G        +S G  HS ++T+ G VY FG  + G+LG+    L     P  V  L   V+ V     HT+  T  NE++ +G H    Q  L       +   P   +        ++  ++CG  H +++TD   +Y FG   +G+LGLG+
Sbjct:  115 ERVRFTACGTNHTLVSTSRGEIFAAGRNSEGQLGL-GHCEERTSFQQ-------LHPFCDGAPLKQ------LSAGCNTSAAL-------TEDGRLFMWGDNSVGQLGLGSENLVLFPKLLKVDRSVTG--------ISCGLNHSALITDIGDVYTFGEAADGRLGLSADQLANHRQPQRVGSLE-GVLQVSCGGTHTLALT-ENELYAFG-HGEFGQLGLGTFDFQADSPAPVGHF-----RKGRVTHVTCGENHTALITDGGLLYTFGDGRYGKLGLGD 358          

Query: 3013 ISLGKNHALILTESGSLYSAGTNECGQLGIENHVLKQNSFVNKNQCLSIIHPMLINIELNSDECIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHGDIDDQFVSKRLIFDFNNSGSGQEFPI-ELSMGCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKSLVPNL--VDRLPPAVIHVDTKYFHTVCCTASNEIFTWGIHPNIWQNSLNHEKSHGEISIPESIYTGDLLSNQK----------IAQISCGTCHASILTDKQFVYCFGSNVWGQLGLGNRKDNKNLVEVNIPVPIDFVSSDDGITIAMSKSENSTKLFVWG 3960
            IS G +H+  +TE G L+  G+N  GQLG+E+                I  P+ +   L  +   F+ A G  H+   +VSTS       +F  G    GQLG G  +++  S + +  F +       P+ +LS GC  S  LT  G ++ +G+NS GQLG+ +    L P L  VDR   +V  +     H+   T   +++T+G            E + G + +     + D L+N +          + Q+SCG  H   LT+ + +Y FG   +GQLGLG         + + P P+       G    ++  EN T L   G
Sbjct:   68 ISCGHSHSAFVTEHGRLFVFGSNSSGQLGLESKG-------------PITKPVCVKA-LKHERVRFT-ACGTNHT---LVSTSR----GEIFAAGRNSEGQLGLGHCEER-TSFQQLHPFCDGA-----PLKQLSAGCNTSAALTEDGRLFMWGDNSVGQLGLGSENLVLFPKLLKVDR---SVTGISCGLNHSALITDIGDVYTFG------------EAADGRLGL-----SADQLANHRQPQRVGSLEGVLQVSCGGTHTLALTENE-LYAFGHGEFGQLGLGTFD-----FQADSPAPVGHFRK--GRVTHVTCGENHTALITDG 340          

Query: 3262 HTTQNSHVFTWGWGVHGQLGHGDIDDQFVSKRLIFDFNNSGSGQEFPIELSMGCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKSLVPNLVDRLPPAVIHVDT-KYFHTVCCTASNEIFTWGIHPNIWQNSLNHEKSHGEISIPESIYTGDLLSNQKIAQISCGTCHASILTDKQFVYCFGSNVWGQLGLGN 3834
             TT++  VFT+G           I D   SK   F   N     + P+ +S G  HS  +T  G ++ FG+NS GQLG+++      P  V  L    +        HT+  T+  EIF  G +    Q  L H +             G  L      Q+S G   ++ LT+   ++ +G N  GQLGLG+
Sbjct:   35 QTTESGAVFTFG--------KSQIADSVPSK---FWLKN-----DKPVLISCGHSHSAFVTEHGRLFVFGSNSSGQLGLESKGPITKPVCVKALKHERVRFTACGTNHTLVSTSRGEIFAAGRNSE-GQLGLGHCEERTSFQQLHPFCDGAPLK-----QLSAGCNTSAALTEDGRLFMWGDNSVGQLGLGS 204          

Query: 2932 LGFIKEKSNRILLLPK--SIESGKEIIRQISLGKNHALILTESGSLYSAGTNECGQLGIENHVLKQNSFVNKNQCLSIIHPMLINIELNSDECIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHGDIDDQFVSKRLIFDFNNSGSGQEFPIELSMGCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKS-LVPNLVDRL---PPAVIHVDTKYFHTVCCTASNEIFTWGIHPNIWQNSLNHEKSHGEISIPESIYTGDLLSNQKIAQISCGTCHASILTDKQFVYCFGSNVWGQLG 3825
            LG I E+   I++ P+  S  +GK ++  +  G+ H + L   G++Y+ G N+ GQLG E    K    V  +                  + I +++ G+ H+ A+            VF WG    GQLG  +++D     R I   +     +   ++++ G  HS+ L+ +G ++ +G N YGQLG+     S L P LV  L   P A I       H+   T S  +F WG +    Q  LN    + +   P  + T   L +Q++  I CG  H + LT +  V+ FG+  +GQLG
Sbjct:   14 LGGIDEE---IVVEPRKCSFFNGK-LVWDVGCGRRHTVFLLGDGTVYTCGCNDLGQLGHEKTRKKPEQVVALDA-----------------QNIVAVSCGESHTLAL-------NDKGQVFAWGQASEGQLGLANMEDCVRVPRNIKSLS-----EVHIVQVTCGYRHSLALSRRGQIFSWGQNKYGQLGLGKEGPSVLTPQLVQSLLGIPFAQISAGGA--HSFGLTLSGAVFGWGRN-KFGQLGLN---DNSDRCAPCLLKT---LRSQRVVYICCGEDHTAALTKEGGVFTFGAGGYGQLG 275          

Query: 3283 VFTWGWGVHGQLGHGDIDDQFVSKRLIFDFNNSGSGQEFPIELSMGCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKSLVPNLVDRLPPA-VIHVDTKYFHTVCCTASNEIFTWGIHPNIWQNSLNHEKSHGEISIPESIYTGDLLSNQKIAQISCGTCHASILTDKQFVYCFGSNVWGQLGLGNRKDN---KNLVEVNIPVPIDFVSSDDGITIAMSKSENSTKLFVWGR 3963
            +  WG   +GQLG G ID++ V +     F N     +   ++  G  H+V L   G VY  G N  GQLG +  +K   P  V  L    ++ V     HT+      ++F WG      +  L        + +P +I +   LS   I Q++CG  H+  L+ +  ++ +G N +GQLGLG    +     LV+  + +P   +S+    +  ++    S  +F WGR
Sbjct:    1 MLCWGNASYGQLGLGGIDEEIVVEPRKCSFFNG----KLVWDVGCGRRHTVFLLGDGTVYTCGCNDLGQLGHEKTRKK--PEQVVALDAQNIVAVSCGESHTLALNDKGQVFAWG---QASEGQLGLANMEDCVRVPRNIKS---LSEVHIVQVTCGYRHSLALSRRGQIFSWGQNKYGQLGLGKEGPSVLTPQLVQSLLGIPFAQISAGGAHSFGLTL---SGAVFGWGR 216          

Query: 2971 LPKSIESGKEI-IRQISLGKNHALILTESGSLYSAGTNECGQLGIENHVLKQNSFVNKNQCLSIIHPMLINIELNSDECIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHGDIDDQFV--------SKRLIFDFNNSGSGQEFPIELSMGCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKSLVPNLVDRLPPAVI-HVDTKYFHTVC-CTASNEIFTWGIHPN 3636
            +P++I+S  E+ I Q++ G  H+L L+  G ++S G N+ GQLG+              +  S++ P L+   L        I+AG  HS  + +S +       VF WG    GQLG  D  D+          S+R+++              +  G  H+  LT +G V+ FG   YGQLG  T    + P  V  L   V+  +     HT+    +S +I ++G+  N
Sbjct:  127 VPRNIKSLSEVHIVQVTCGYRHSLALSRRGQIFSWGQNKYGQLGL------------GKEGPSVLTPQLVQSLLGIP--FAQISAGGAHSFGLTLSGA-------VFGWGRNKFGQLGLNDNSDRCAPCLLKTLRSQRVVY--------------ICCGEDHTAALTKEGGVFTFGAGGYGQLGHNTTNHEINPRKVFELMGNVVTQISCGRQHTMAFIPSSGKIDSFGLGGN 324          

Query: 3283 VFTWGWGVHGQLGHGDIDDQFVSKRLIFDFNNSGSGQEFPIELSMGCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKSL-VPNLVDRLPPA-VIHVDTKYFHTVCCTASNEIFTWGIHPNIWQNSLNHEKSHGEISIPESIYTGDLLSNQKIAQISCGTCHASILTDKQFVYCFGSNVWGQLGLGNRKDN--KNLVEVNIPVPIDFVSSDDGITIAMSKSENSTKLFVWGRCGHSLIQEHIKN 3999
            V+T G    GQLGH     +   + +  D  N        + +S G  H++ L +KG V+ +G  S GQLG+  ++  + VP  +  L    ++ V   Y H++  +   +IF+WG +       L   K    +  P+ + +   L     AQIS G  H+  LT    V+ +G N +GQLGL +  D     L++      + ++   +  T A++K      +F +G  G+  +  +  N
Sbjct:   55 VYTCGCNDLGQLGHEKTRKK-PEQVVALDAQNI-------VAVSCGESHTLALNDKGQVFAWGQASEGQLGLANMEDCVRVPRNIKSLSEVHIVQVTCGYRHSLALSRRGQIFSWGQNK---YGQLGLGKEGPSVLTPQLVQS---LLGIPFAQISAGGAHSFGLTLSGAVFGWGRNKFGQLGLNDNSDRCAPCLLKTLRSQRVVYICCGEDHTAALTKEGG---VFTFGAGGYGQLGHNTTN 280          

Query: 3463 CFGNNSYGQLGVQTLQKSLV--PNLVDRLPPAVI-HVDTKYFHTVCCTASNEIFTWGIHPNIWQNSLNHEKSHGEISIPESIYTGDLLSNQKIAQISCGTCHASILTDKQFVYCFGSNVWGQLGLGNRKDN-------KNLVEVNIPVPIDFVSSDDGITIAMSKSENSTKLFVWGRCGHSLIQEHIKNPVSDTLKPQLL 4032
            C+GN SYGQLG+  + + +V  P         ++  V     HTV       ++T G +       L HEK+  +   PE +     L  Q I  +SCG  H   L DK  V+ +G    GQLGL N +D        K+L EV+I      V    G   +++ S    ++F WG+  +  +    + P    L PQL+
Sbjct:    3 CWGNASYGQLGLGGIDEEIVVEPRKCSFFNGKLVWDVGCGRRHTVFLLGDGTVYTCGCND---LGQLGHEKTRKK---PEQVVA---LDAQNIVAVSCGESHTLALNDKGQVFAWGQASEGQLGLANMEDCVRVPRNIKSLSEVHI------VQVTCGYRHSLALSRRG-QIFSWGQNKYGQLGLGKEGP--SVLTPQLV 184          

Query: 2995 KEIIRQISLGKN---HALILTESGSLYSAGTNECGQLGIENHVLKQNSFVNKNQCLSIIHPMLINIELNSDECIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHGDIDDQFVSKRLIFDFNNSGSGQEFPIELSMGCFHSVILTNKG-FVYCFGNNSYGQLGVQTLQKSLVPNLVDRLPPAVIH-VDTKYFHTVCCTASNEIFTWGIHPNIWQNSLNHEKSHGEISIPESIYTGDLLSNQKIAQISCGTCHASILTDKQFVYCFGSNVWGQLGLGN 3834
            +  +++IS  +    H L +T  G ++S G  + G+LG        NS   K       +P LI   L   + +  ++AG  HS ++       T++  ++TWG G  G+LGHGD + + +   L+ D +N G       +++ G  H++ ++  G  V+ FG    G+LG     +   P +++ L    I  V      ++  T++ +++ WG         L    S      P+ I   + L+  +I  ISCG  H   LT    VY +G+N  GQ G G+
Sbjct:  461 QRAVKKISSSRGSDGHTLAVTMEGEVFSWGDGDYGKLG------HGNSSTQK-------YPKLIQGPLQG-KVVVCVSAGYRHSASV-------TEDGELYTWGEGDFGRLGHGDSNSRNIPT-LVKDISNVG-------QVACGSSHTIAVSQDGRIVWSFGGGDNGKLGHGDTNRVYKPKVIEALQGMFIRKVCAGSQSSLALTSTGQLYAWGC-----GACLGCGSSEATALRPKLI---EDLACTRIVDISCGDSHCLALTHDNEVYAWGNNSMGQCGQGH 708          

Query: 2971 LPKSIESGKE-IIRQISLGKNHALILTESGSLYSAGTNECGQLGIENHVLKQNSFVNKNQCLSIIHPMLINIELNSDECIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHGDIDDQFV-------------SKRLIFDFNNSGSGQEFPI------ELSMGCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKSLVPNLV---DRLPPAVIHVDTKYFHTVCCTASNEIFTWGIHPNIWQNSLNHEKSHGEISIPESIYTGDLLSNQKIAQISCGTCHASILTDKQFVYCFGSNVWGQLGLGNRKDNKN 3852
            +P+ I++ KE +I   + G++H L LT++G++Y+ G N  GQLG+             NQ  ++  P  I   + S   +  +A G   S  I         + ++F++G   +GQLGH + D +++              +RL      +  GQ   +      +++ G  H++ L  +G V+ +G   YG+LG    +  L+P LV   DR  PAV  V   Y  T        ++ WG          +   S      P++++    L    +  ++CG     I +D+  +       +G+LG G  K   +
Sbjct:   96 VPRIIDTLKECVIVDGACGRSHTLCLTDTGTVYAFGENRLGQLGL------------GNQTDAVPSPTQI---VYSGRQVVKVACGAEFSVFIDC-------DGNLFSFGCPEYGQLGH-NTDGRYIVRAQRIEFVCELAPRRLARFIEKTRDGQVLTVRGVVVRDVACGANHTIALDTRGRVFTWGFGGYGRLGHAEQKDELLPRLVKLLDRPAPAVNSVRAGYSCTFAINVVGTLYFWG----------STNTSRDPTMYPKAVHD---LCGTHVRSLACGKSSILITSDESTMSWGPWPTYGELGYGEGKQRSS 376          

Query: 3283 VFTWGWGVHGQLGHGDIDDQFVSKRLIFDFNNSGSGQEFPIELSMGCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKSLVPNLVDRLPPAVIHVDTKYFHTVCCT-------ASNEIFTWGIHPNIWQNSLNHEKSHGEISIPESIYTGDLLSNQKIAQ--------------------ISCGTCHASILTDKQFVYCFGSNVWGQLGLGNRKDN--KNLVE-VNIPVP-IDFVSSDDGITIAMSKSENSTKLFVWG 3960
            V++WG G  GQLGHGD     V  R+I             ++ + G  H++ LT+ G VY FG N  GQLG+   Q   VP+     P  +++   +     C             +F++G  P   Q  L H      I   + I     L+ +++A+                    ++CG  H   L  +  V+ +G   +G+LG   +KD     LV+ ++ P P ++ V +    T A++       L+ WG
Sbjct:   75 VYSWGRGEKGQLGHGDTCRVDV-PRIIDTLKEC-----VIVDGACGRSHTLCLTDTGTVYAFGENRLGQLGLGN-QTDAVPS-----PTQIVYSGRQVVKVACGAEFSVFIDCDGNLFSFGC-PEYGQ--LGHNTDGRYIVRAQRIEFVCELAPRRLARFIEKTRDGQVLTVRGVVVRDVACGANHTIALDTRGRVFTWGFGGYGRLGHAEQKDELLPRLVKLLDRPAPAVNSVRAGYSCTFAINVVGT---LYFWG 313          

Query: 3427 HSVILTNKGFVYCFGNNSYGQLGVQTLQKSLVPNLVDRLPPAVIHVDTK--YFHTVCCTASNEIFTWGIHPNIWQNSLNHEKSHGEISIPESIYTGDLLSNQKIAQISCGTCHASILTDKQFVYCFGSNVWGQLGLGNRKDNKNLVEVNIPVPIDFV 3891
            HS++++ +G VY +G    GQLG     +  VP ++D L   VI VD      HT+C T +  ++ +G +  + Q  L ++     +  P  I    + S +++ +++CG   +  +     ++ FG   +GQ  LG+  D + +V       I+FV
Sbjct:   65 HSLLISTRGLVYSWGRGEKGQLGHGDTCRVDVPRIIDTLKECVI-VDGACGRSHTLCLTDTGTVYAFGEN-RLGQLGLGNQTD--AVPSPTQI----VYSGRQVVKVACGAEFSVFIDCDGNLFSFGCPEYGQ--LGHNTDGRYIVRAQ---RIEFV 208          

Query: 2926 KLLGFIKEKSNRILLLPKSIESGKEI-IRQISLGKNHALILTESGSLYSAGTNECGQLGIENHVLKQNSFVNKNQCLSIIHPMLIN-IELNSDECIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHGDIDDQFVSKRLIFDFNNSGSGQEFPIELSMGCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKSLVPNLVDRLPPAVIHVDTKYFHTVCCTASNEIFTWGIHPNIWQNSLNHEKSHGEISIPESIYTGDLLSNQKIAQISCGTCHASILTDKQFVYCFGSNVWGQLGLGNRKDNKNLVEVNIPVP---IDFVSSDDGITIAMSKSENSTKLFVWG 3960
            K++G +  K       PK ++    + +RQ++ G    + LTE G ++S G++  G +G            N    + ++ PM +    +N    +  I+ GD H  A+       T++  V+ WG G +G+LG      +F  KR+        S +    E+  G   +  LT +G V   GNN + +LG+      L             + +T  FH V            + P + +                       LS  KI  IS G  H++++     +  FG N  GQLG G+ K +  +V    P+    I  VS  DG TIA ++++N   ++ WG
Sbjct:  382 KMVGQLGHKDKASYRQPKRVDKLLGLAVRQVACGDEFTVCLTEQGEVFSFGSDYYGCMG-----------CNGELGVEVLEPMPVQFFNINP---VTQISCGDCHVMAL-------TRSGAVYAWGCGEYGRLGLETDATEFYPKRVPL------SNRWKITEVCCGTDGTFFLTAQGKVLACGNNEFNKLGLNQCTSGLR------------NRETSVFHEVIMK---------LMPTLVKQ----------------------LSIYKIRSISGGKTHSAVIDVCGRLLTFGHNKHGQLGTGDFKKHLGIVLHKGPLVGKLITMVSCGDGFTIAATEADN--HIYAWG 659          

Query: 2932 LGFIKEKSNRI-----LLLPKSI-----ESGKEIIRQISLGKNHALILTES-GSLYSAGTN---ECGQLGIENHVLKQNSFVNKNQCLSIIHPMLINIELNSDECIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHGDIDDQFVSKRLIFDFNNSGSGQEFPIELSMGCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKSLVPNLVDRLP-PAVIHVDTKYFHTVCCTASNE---IFTWGIHPNIWQNSLNHEKSHGEISIPESIYT-GDLLSNQKIAQISCGTCHASILTDKQFVYCFGSNVWGQLGLGNRKDNKNLVEVNIPVPIDFVSSDDGITIAMSKS 3930
            +GF + +S+R      +L P  +     E  +  + Q++ G+ H+L+LT++ G+++S G N   +CG++ IE+ V K +  ++K   +  I   ++ +    D  +F                   T+   ++  GWG  GQ G G  +     KRL  D     SG+      S G F  + ++  G ++ +GN+ Y QL   T   ++  N+   +P   V  V         C   NE   +F WG    I        ++     IP S++   +   + ++  + CG  H + +  +  ++ +G N+ G LG+G   D      V +   +  V+     ++A++K+
Sbjct:  104 IGFHRSRSDRTKSYDYILEPSPVPLPLVEHQQTRVLQVACGRAHSLVLTDNEGAVFSMGNNAYGQCGRVIIEDEVYKGSRLIHK---IEGIEGKVVEVVCGQDHSLFR------------------TEKGELYACGWGADGQTGLGSYEMCSTPKRLGGDL----SGEPVAQVASYGDF-CLAVSESGELFGWGNSEYRQLAAIT--DAVQINVPKHIPLKNVGKVKMAAAGGTICGILNEEGEVFVWGY--GILGKGPRLSETETPEQIPPSLFGRTEFDPDIRVKTLRCGLHHFAAVNTRGELFSWGKNMRGCLGIGRPDDQYFPWRVTVAGEVVDVACGVDHSVALAKT 425          

Query: 3004 IRQISLGKNHALILTESGSL--YSAGTNECGQLGIENHVLKQNSFVNKNQCLSIIHPMLIN--IELNSDECIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHGDIDD----QFVSKRLIFDFNNSGSGQEFPIELSMGCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKSLVPNLVDRLPPAVIHVDTKYFHTVC--CTASNEIFTWGIHPNIWQNSLNHEK-SHG-----------EISIPESIYTGDLLSNQKIAQISCGTCHASILTDKQFVYCFGSNVWGQLGLGNRKDNKNLVEVNIPVPIDF--------VSSDDGITIAMSKSENSTKLFVW-----GRCGHSLIQEHIKNPV 4005
            + Q+++G+     +T SG L  + A     G   +   V               + P L++  +E  S   I  ++ GD  +  +       T    + T+G G  G LGHG   D    + V   L ++            ++S G  H + ++N+  V+ +G    G+LG+   +  L P  V   PP      T +    C   T+S ++   G   N   N L  +K SH            E S+  S      L   ++  ++ GT H++ +TD    Y FGSN  GQLG G R  ++       P P+D         V+  D  T+A+++     ++F W     GR G +  +  +  PV
Sbjct:  256 VLQVAVGRTQRAGVTRSGRLIVWEASPGTVGDAALPGSV-------------GSVQPQLVSRFLEGQSGVTIQHVSCGDLFTACL-------TDRGILMTYGSGSSGCLGHGSYSDVAQPKIVEALLGYEIT----------QMSCGMSHVLAVSNEQEVFAWGRGDNGRLGLGNQELHLCPQPVAVPPP--YEPCTAHCGIDCSMVTSSGKLLACGS--NRRYNKLGLDKISHDGDDAACPAEQTEESLVLSPVQSSPLDGARVVHVALGTAHSAAVTDTGTCYTFGSNQHGQLGGGARTSSR------APQPVDGLGGVKVVQVTCGDAFTVAVAE---GGQVFTWGKAARGRLGRTDGEACVPGPV 581          

Query: 2935 GFIKEKSNRILLLPKSIESGKEIIRQISLGKNHALILTESGSLYSAGTNECGQLGIENHVLKQNSFVN-KNQCLSIIHPMLINIELNSDECIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHGDIDD 3339
            G +  K  R L LP ++     +IR I+ G++H+LIL++ G LYS G  +  ++GI    L + ++ +   +  ++  P     +LN+     S+AAG +HS A+        QN   ++WG+G    +G G  +D
Sbjct:  315 GALVTKPKR-LALPDNV-----VIRSIAAGEHHSLILSQDGDLYSCGRLDMFEVGIPKDNLPEYTYKDVHGKARAVPLP----TKLNNVPKFKSVAAGSHHSVAVA-------QNGIAYSWGFGETYAVGLGPFED 433          

Query: 3013 ISLGKNHALILTESGSLYSAGTNECGQLGIENHVLKQNSFVNKNQCLSIIHPMLINIELNSDECIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHGDIDDQFVSKRLIFDFNNSGSGQEFPIELSMGCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKSLVPNLVDRLPPAVIH-VDTKYFHTVCCTASNEIFTWGIHPNIWQNSLNHEKSHGEISIPESIYTGDLLSNQKIAQISCGTCHASILTDKQFVYCFGSNVWGQLGLGNRKDNKNLVEVNIPVPIDFVSSDD---GITIAMSKSENSTKLFVWGR--CGHSL 3978
            ++ G  H L L   G +YS G++E GQLG             +        P+ +  EL+  +CI ++  G YHS A+       + +  V++WGWGVHGQLG   I+D  +   +      S SG  F  +L+ G  H+ +LT +G VY FG   YGQLG+ T  K  +P LV  L    I+ +    F TV  ++  ++F WG  P+ +                            +   I CG  H   +T+ + V+ +G N  GQLG     D+     V   +   FV++       ++AM   + + +++VWGR   G SL
Sbjct:   92 VACGIEHTLALCRDG-VYSWGSSEYGQLG-------------QGDTQQHTRPVYVT-ELSDKKCI-AVVCGHYHSLAL-------SADQQVYSWGWGVHGQLGLDSIEDALLPSHV-----TSLSGA-FVTQLAAGYSHTAVLTTEGKVYTFGGGLYGQLGLGTTSKQTLPQLVQALEKDRIYLICCGSFETVAVSSEQKLFNWGRSPHYF----------------------------RFHMIHCGNWHYLAVTEARQVFTWGFNDHGQLGHSTSMDHLLFPTVVQKLNESFVATASVGAEFSVAM---DATGQVWVWGRSDSGQSL 359          

Query: 3214 IAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHGDIDDQFVSKRLIFDFNNSGSGQEFPIELSMGCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKSLVPNLVDRLP-PAVIHVDTKYFHTVCCTASNEIFTWG--IHPNIWQNSLNHEKSHGEISIPESIYTGDLLSNQKIAQISCGTCHASILTDKQFVYCFGSNVWGQLGL--GNRKDNKNLVEVNIPVPIDFVSSDDGITIAMSKSENSTKLFVWGRCGH 3972
            ++ G +H+  +  S         V+TWG    G+LGHGD+ ++   K + F        +   + ++ G  H++ L   G VY +G++ YGQLG    Q+   P  V  L     I V   ++H++  +A  ++++WG  +H  +  +S+       +  +P  + +   LS   + Q++ G  H ++LT +  VY FG  ++GQLGL   +++    LV+      I  +      T+A+S  +   KLF WGR  H
Sbjct:   35 LSCGQHHTAVVSAS-------GDVYTWGKSHKGRLGHGDLIEE-EGKSMPFRVEILHMHRIKVLSVACGIEHTLALCRDG-VYSWGSSEYGQLGQGDTQQHTRPVYVTELSDKKCIAVVCGHYHSLALSADQQVYSWGWGVHGQLGLDSIE------DALLPSHVTS---LSGAFVTQLAAGYSHTAVLTTEGKVYTFGGGLYGQLGLGTTSKQTLPQLVQALEKDRIYLICCGSFETVAVSSEQ---KLFNWGRSPH 271          

Query: 3163 HPMLINIELNSDECIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHGDIDDQFVSKRLIFDFNNSGSGQEFPIELSMGC--FHSVIL---TNKGFVYCFGNNSYGQLGV--QTLQKSLVPNLVDRLPPAVIHVDTKYFHTVCCTASNEIFTWGIHPNIWQNSLNHEKSHGEISIPESIYTGDLLSNQKIAQISCGTCHASILTDKQFVYCFGSNVWGQLG--LGNRKDNKNL--VEVNIPVPIDF----VSSDDGITIAMSKSENSTKLFVWGR 3963
            HP ++   L  D  I  +A G  H+ A+       +++  VF+WG G  G+LG G + D+F   R+         G E      + C  FHS  +   + +G ++ FG N YGQLG+    L  S +  +       +  V    FH+        ++ WG + +    + N+  +    S+P  +  G+ L +  + +++CG  H++ +T K  ++C G N +GQLG  L + +D+     V V + VP DF    V+  D  T  ++   +  ++F WGR
Sbjct:  230 HPHVVEALLGKD--IRKVACGATHTLAL-------SKDGEVFSWGSGYGGRLGQGHLRDRFTPIRIC--------GLESLNLTQVACNEFHSAAVCACSKQGALFSFGENDYGQLGIPEDKLLTSYIQCVSSLSEHKISRVACGSFHSAALAEHGSLWLWGCNESGQLGNGNYTST----SLPSLLEAGNDLRHDAVMEVACGDQHSAFITKKGRMFCCGDNTYGQLGAHLNDNQDDHVTYNVAVRVRVPTDFRCVHVACGDSHTAVVT---DGGEIFTWGR 487          

Query: 2974 PKSIES--GKEIIRQISLGKNHALILTESGSLYSAGTNECGQLGIENHVLKQNSFVNKNQCLSIIHPMLINIELNSDECIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHGDIDDQFVSKRLIFDFNNSGSG-QEFPI-ELSMGCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKSLVPNLV----DRLPPAVIHVDTKYFHTVCCTASNEIFTWG--IHPNIWQNSLNHEKSHGEISIPESIYTGDLLSNQKIAQISCGTCHASILTDKQFVYCFGSNVWGQLGLGNRKDNKNLVEVNI 3870
            P  +E+  GK+I R+++ G  H L L++ G ++S G+   G+LG       Q    ++   + I     +N+          +A  ++HS A+       ++   +F++G   +GQLG           +L+  +    S   E  I  ++ G FHS  L   G ++ +G N  GQLG      + +P+L+    D    AV+ V     H+   T    +F  G   +  +  +  +++  H   ++   +    + ++ +   ++CG  H +++TD   ++ +G    G+LG G+  +     E+ I
Sbjct:  231 PHVVEALLGKDI-RKVACGATHTLALSKDGEVFSWGSGYGGRLG-------QGHLRDRFTPIRICGLESLNLT--------QVACNEFHSAAVCA----CSKQGALFSFGENDYGQLG-------IPEDKLLTSYIQCVSSLSEHKISRVACGSFHSAALAEHGSLWLWGCNESGQLGNGNYTSTSLPSLLEAGNDLRHDAVMEVACGDQHSAFITKKGRMFCCGDNTYGQLGAHLNDNQDDHVTYNVAVRVR---VPTDFRCVHVACGDSHTAVVTDGGEIFTWGRGKGGRLGHGDNLNRHLPTEIEI 509          

Query: 2971 LPKSIESGKEI----IRQISLGKNHALILTESGSLYSAGTNECGQLGIENHVLKQNSFVNKNQCLSIIHPMLINIELNSDECIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHGD 3330
            LP  +E+G ++    + +++ G  H+  +T+ G ++  G N  GQLG         + +N NQ   + + + + + + +D     +A GD H+  +       T    +FTWG G  G+LGHGD
Sbjct:  390 LPSLLEAGNDLRHDAVMEVACGDQHSAFITKKGRMFCCGDNTYGQLG---------AHLNDNQDDHVTYNVAVRVRVPTDFRCVHVACGDSHTAVV-------TDGGEIFTWGRGKGGRLGHGD 497          

Query: 2914 RCQIKLLGFIKEKSNRILLLPKSIESGK--EIIRQISLGKNHALILTESGSLYSAGTNECGQLGIENHVLKQNSFVNKNQCLSIIHPMLINIELNSDECIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHGDIDD---QFVSKRLIFDFNNSGSGQEFPIELSMGCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKSL---VPNL-VDRLPPAVIHVDTKYFHTVCCTASNEIFTWGIHPNIWQNSLNHEKSHGEISIPESIYTGDLLSNQKIAQISCGTCHASILTDKQFVYCFGSNVWGQLG 3825
            +C    LG + E     +  P+ +E+ +    +R++S G NH   L + G++Y+ G+NE GQLG      ++ S  N     +I               I  +  G  H+ A+       +    VF WG   +GQ+G G       Q + K L       G  +   ++++ GC HS+ LT  G ++C+G+NS GQLG+     S+    P L ++ +P  +I       H+   ++S  +F WG      +N       H     P       L S Q +  +SCG  H ++LT    V+ FG    GQLG
Sbjct:    6 KCSEGQLG-VGETEQEFISTPRLLENLEFSSNVREVSCGWNHTAFLCKDGTVYTCGSNEFGQLG------QEKSHTNPESVHAI-----------ETFTITKVTCGKAHTVAV-------SDQGLVFAWGDNSYGQIGLGSKVKEKVQTIPKML------KGLAKMSVVQIACGCNHSMALTISGHLFCWGDNSSGQLGIGKTHSSMSEPAPVLSLNGVPFMLISAGGA--HSFALSSSGALFGWG------KNEYGQLGVHDTTDRPLPTLLKSLRS-QGVCYVSCGEKHTAVLTSDGGVFTFGCGTSGQLG 278          

Query: 3283 VFTWGWGVHGQLGHGDIDDQFVS-KRLIFDFNNSGSGQEFPIELSMGCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKSLVPNLVDRLPP-AVIHVDTKYFHTVCCTASNEIFTWGIHPNIWQNSLNHEKSHGEISIPESIYTGDLLSNQKIAQISCGTCHASILTDKQFVYCFGSNVWGQLGLG----NRKDNKNLVEVNIPVPIDFVSSDDGITIAMSKSENSTKLFVWGR--CGHSLIQEHIKNPVSDTLK 4020
            +F WG    GQLG G+ + +F+S  RL+ +   S + +E    +S G  H+  L   G VY  G+N +GQLG +    +  P  V  +    +  V     HTV  +    +F WG + +  Q  L  +      +IP+ +     L+   + QI+CG  H+  LT    ++C+G N  GQLG+G    +  +   ++ +N  VP   +S+    + A+S   +S  LF WG+   G   + +    P+   LK
Sbjct:    1 MFCWGKCSEGQLGVGETEQEFISTPRLLENLEFSSNVRE----VSCGWNHTAFLCKDGTVYTCGSNEFGQLGQEKSHTN--PESVHAIETFTITKVTCGKAHTVAVSDQGLVFAWGDN-SYGQIGLGSKVKEKVQTIPKMLKG---LAKMSVVQIACGCNHSMALTISGHLFCWGDNSSGQLGIGKTHSSMSEPAPVLSLN-GVPFMLISAGGAHSFALS---SSGALFGWGKNEYGQLGVHDTTDRPLPTLLK 240          

Query: 2920 QIKLLGFIKEKSNRILLLPKSIES-GKEIIRQISLGKNHALILTESGSLYSAGTNECGQLGIENHVLKQNSFVNKNQCLSIIHPMLINIELNSDECIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHGDIDDQFVSKRLIFDFNNSGSGQEFPIELSMGCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKSLVPNLVDRLPPAVI-HVDTKYFHTVC-CTASNEIFTWG-------------------IHPNIWQNSLNHEKSHGEISIPESIYTGDLLSNQKIAQISCGTCHASILTDKQFVYCFGSNVWGQLGLGNRKDNKNLVEVNIPVPIDFVSSDDGITIAMSKSENSTKL---FVWGRCGHSLIQEHIKNPVSDTLKPQLLIEYQHVVDNHL 4065
            QI L   +KEK   I   PK ++   K  + QI+ G NH++ LT SG L+  G N  GQLGI             +  +S   P+L    LN    +  I+AG  HS A+  S +       +F WG   +GQLG  D  D+ +   L+    + G        +S G  H+ +LT+ G V+ FG  + GQLG  +      P  V  L  +V+  +     HT+    +S  ++T+G                        W  S N +    E      +YT        + +I  G  H   +        +G    G   +   + +++++ +++PV +D V      TIA   S+ S KL   F    C +    +++ +P    + P L+  Y H + +HL
Sbjct:  116 QIGLGSKVKEKVQTI---PKMLKGLAKMSVVQIACGCNHSMALTISGHLFCWGDNSSGQLGIGK----------THSSMSEPAPVL---SLNGVPFML-ISAGGAHSFALSSSGA-------LFGWGKNEYGQLGVHDTTDRPLPT-LLKSLRSQGV-----CYVSCGEKHTAVLTSDGGVFTFGCGTSGQLGHNSNHHEYTPRKVFELMGSVVTQIACGRAHTLALVPSSGRVYTFGRGGDGQLGLGVTNNCNSPMTAKGPWLRSNNIKSMLPEADGDSVVYT--------VRRIDAGGDHCFAMASS-----YGDETDGPEDMRLPRPSQSILHLSVPVTMDLVKR---ATIASDLSDVSEKLEIIFSSLACLNGSFLDNVVHPYVMPIHPCLIPLYVHFIHSHL 476          

Query: 3031 HALILTESGSLYSAGTNECGQLGIENHVLKQNSFVNKNQCLSIIHPMLINIELNSDECIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHGDIDDQFVSKRLIFDFNNSGSGQEFPIELSMGCFHSVILTNKG-FVYCFGNNSYGQLGVQTLQKSLVPNLVDRLPPAVIHVDTKYFHTVCC--------TASNEIFTWGIHPNIWQNSLNHEKSHGEISIPESIYTGDLLSNQKIAQISCGTCHASILTDKQFVYCFGSNVWGQLGLGN 3834
            H L LT  G +YS G  + G+LG  N           +Q   I  P L+   L  ++ +  IAAG  HS A+       T++  ++TWG G +G+LGHGD + + V  + + D  N G       +++ G  H+V ++  G  V+ FG+   G+LG     +   P +++ L   VI         VCC        T++ +++ WG  P++   S++   +  ++ +         L +  +  IS G  H   LT    VY +G+N  GQ G G+
Sbjct:  461 HTLALTLDGKVYSWGDGDYGKLGHGN-----------SQTQKI--PKLVEGALG-NKVVCCIAAGYRHSAAV-------TEDGELYTWGEGDYGRLGHGDNNSRNVPVQ-VKDVANVG-------QVACGSAHTVCVSQDGQTVWSFGSGDNGKLGHSDTNRVYKPKVIEALQGMVI-------RKVCCGSQCSLALTSTGQVYVWGCGPSLGTGSVDATSATPKLLLA--------LQSHSVVDISVGDSHCVALTQDNNVYAWGNNSMGQCGQGH 693          

Query: 3274 NSHVFTWGWGVHGQLGHGDIDDQFVSKRLIFDFNNSGSGQEFPIELSMGCFHSVILTNKGFVYCFGNNSYGQLGV-----QTLQKSLVPNLVDR-LPPAVIHVDTKYFHTVCCTASNEIFTWGIHPNIWQNSLNHEKSHGEISIPESIYTGDLLSNQKIAQISCGTCHASILTDKQFVYCFGSNVWGQLGLGNRKDNKNLVEVNIPVPIDFVSSDDGITIAMSKSENSTKLFVW-------GRCGHS 3975
            N  V+ WG     QL  G +D   V K L   F   GS Q+    +  G + + ++   GFV+  G  SYG+LG+     QT  K L  N  +  L  +V        HT+  T   ++++WG   +     L H  S  +  IP+ +     L N+ +  I+ G  H++ +T+   +Y +G   +G+LG G+       V+V     +  V+     T+ +S+   +    VW       G+ GHS
Sbjct:  363 NEEVYVWGSNSSHQLAEGSMDKILVPK-LATSF---GSAQQ----IEAGQYCTFVIFPDGFVHACGKGSYGRLGLGDSTNQTQLKRL--NFDNECLVKSVSSSKGSDGHTLALTLDGKVYSWG---DGDYGKLGHGNSQTQ-KIPKLVEGA--LGNKVVCCIAAGYRHSAAVTEDGELYTWGEGDYGRLGHGDNNSRNVPVQVKDVANVGQVACGSAHTVCVSQDGQT----VWSFGSGDNGKLGHS 589          

Query: 2971 LPKSIES-GKEIIRQISL--GKNHALILTESGSLYSAGTNECGQLGIENHVLKQNSFVNKNQCLSIIHPMLINIELNSDECIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHGDIDDQFVSKRLIFDFNNSGSGQEFP----IELSMGC--FHSVILTNKGFVYCFGNNSYGQLGVQTLQKSLVPNLVDRLP-PAVIHVDTKYFHTVCCTASNEIFTWGIHPNIWQNSLNHEKSHGEISIPESIYTGDLLSNQKIAQISCGTCHASILTDKQFVYCFGSNVWGQLGLGNRKDNKNLVEVN 3867
            +P+ IE+    ++R++S+  G  HA+ LT  G L+S G  E G+LG  N              ++  HP LI+   +S  C+  ++ G  HS AI+ S         ++TWG G +G+LGHGD       K++          Q F     I+++ G     ++ LT+ G V+ +G+  +G+LG    +   VPN V++L    V  V      ++  + S  ++TWG           +   HG  +        D L  +KI  ++ G  H   +TD   V+ +G N  GQ G      N+    VN
Sbjct: 2497 VPRQIENLSSFMVRKVSVHSGGRHAMALTIEGKLFSWGEGEDGKLGHGNR-------------MNCDHPKLIDTFKSS--CVRDMSCGSSHSAAILSS-------GELYTWGLGEYGRLGHGDNYTHLKPKKV----------QSFTSHRVIDIACGSRDAQTLALTDDGTVWSWGDGDFGKLGRGGSEGCSVPNPVEKLQGQGVCKVACGAQFSLALSTSGLVWTWG-------KGDYYRLGHGNDTHVRKPQIVDGLRGKKIVDVAVGALHCLAVTDSGQVFAWGDNDHGQQGNNTTTVNRRPQLVN 2766          

Query: 3001 IIRQISL--GKNHALILTESGSLYSAGTNECGQLGIENHVLKQNSFVNKNQCLSIIHPMLINIELNSDECIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHGDIDDQFVSK--------RLIFDFNNSGSGQEFPIELSMGCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKSLVPNLVDRLPP-AVIHVDTKYFHTVCCTASNEIFTWGIHPNIWQNSLNHEKSHG---EISIPESIYTGDLLSNQKIAQISCGTCHASILTDKQFVYCFGSNVWGQLGLG 3831
            ++R++++  G  HA+ L+  G +YS G  + G+LG            N+N C     P +I  E    + +  I+ G  HS  I       TQN  ++TWG G +G+LGHGD +DQ + K        R+I     SG  Q            ++ LT+   V+ +G+  YG+LG        +P  V+ L    V  V+     +V  T S  ++TWG           +   HG    +  P+ +     L  +K+  I+ G+ H    TD   VY +G N  GQLG G
Sbjct: 3440 VVRKVAVHSGGKHAMALSADGDVYSWGEGDDGKLG----------HGNRNSC---DRPRVI--EALRGKGVIDISCGGSHSACI-------TQNHELYTWGKGRYGRLGHGDSEDQLLPKVVEALRGNRVIDVACGSGDAQ------------TLCLTDDDCVWSWGDGDYGKLGRGGSDGCKIPMKVESLIGLGVSKVECGSQFSVALTRSGAVYTWG-------KGDYYRLGHGVDDHVRRPKRVAA---LQGKKVITIATGSLHCVASTDTGEVYTWGDNDEGQLGDG 3686          

Query: 3031 HALILTESGSLYSAGTNECGQLGIENHVLKQNSFVNKNQCLSIIHPMLINIELNSDECIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHGDIDDQFVSKRLIFDFNNSGSGQEFPIELSMGC--FHSVILTNKGFVYCFGNNSYGQLGVQTLQKSLVPNLVDRLPP-AVIHVDTKYFHTVCCTASNEIFTWGIHPNIWQNSLNHEKSHGEISIPESIYTGDLLSNQKIAQISCGTCHASILTDKQFVYCFGSNVWGQLG 3825
            H L LT  G +YS G+ + G+LG  +   ++              P L+   L   + I  I+ G  HS A+       T    ++TWG G +G+LGHG  +DQ V   +      SG      I+++ G    H++   + G V+ +G+  YG+LG         P  ++RL    V  V      ++  T    ++TWG         L H  +   +  P+ +   + L  + +  +S G+ H   LTD   VYC+G N  GQLG
Sbjct:   28 HFLALTREGEVYSWGSGDGGKLGHGDTSPRE-------------EPTLVT-GLAGKQVI-RISCGSTHSAAV-------TSEGELYTWGRGNYGRLGHGSSEDQLVPVLV------SGLRGHHIIDVACGSGDAHTLAAADDGTVWSWGDGDYGKLGRGGSDGCKNPKSIERLQGLGVCKVYCGAQFSLALTRDGSVWTWGKGEGF---RLGH-GTEDHVRHPKLV---EALDGKHVVDVSVGSIHCLALTDAGEVYCWGRNDQGQLG 260          

Query: 2974 PKSIESGKE-IIRQISLGKNHALILTESGSLYSAGTNECGQLGIENHVLKQNSFVNKNQCLSIIHPMLINIE----------LNSDECIFSIAAGDY-------HSGAIVVSTSHTTQ-------------------NSHVFTWGWGVHGQLGHGDIDDQFVSKRLIFDFNNSGSGQEFPIELSMGCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKSLVPNLVDRLPPAVIHVDTKYFHTVCCTASNEI 3612
            PK I++ K   +R +S G +H+  +  SG LY+ G  E G+LG  ++     + +   +  S     +I+I           L  D  ++S   GD+         G  V +     Q                   +  V+TWG G + +LGHG+  D  V K  I D    G   +  +++++G  H + +T+ G V+ +G+N +GQ G  T         V+R P  V  ++ +    V C +S+ I
Sbjct: 2552 PKLIDTFKSSCVRDMSCGSSHSAAILSSGELYTWGLGEYGRLGHGDNY----THLKPKKVQSFTSHRVIDIACGSRDAQTLALTDDGTVWSWGDGDFGKLGRGGSEGCSVPNPVEKLQGQGVCKVACGAQFSLALSTSGLVWTWGKGDYYRLGHGN--DTHVRKPQIVD----GLRGKKIVDVAVGALHCLAVTDSGQVFAWGDNDHGQQGNNT-------TTVNRRPQLVNGLEGQKITRVACGSSHSI 2784          

Query: 3268 TQNSHVFTWGWGVHGQLGHGDIDDQFVSKRLIFDFNNSGSGQEFPIELSMGCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKSLVPNLVDRLP-PAVIHV--DTKYFHTVCCTASNEIFTWGIHPNIWQNSLNHEKSHGEISIPESIYTGDLLSNQKIAQISCGTCHASILTDKQFVYCFGSNVWGQLGLGNRK-----------DNKNLVEVNI 3870
            T+   V++WG G  G+LGHGD      S R         +G++  I +S G  HS  +T++G +Y +G  +YG+LG  + +  LVP LV  L    +I V   +   HT+       +++WG         L    S G    P+SI   + L    + ++ CG   +  LT    V+ +G     +LG G              D K++V+V++
Sbjct:   33 TREGEVYSWGSGDGGKLGHGD-----TSPREEPTLVTGLAGKQV-IRISCGSTHSAAVTSEGELYTWGRGNYGRLGHGSSEDQLVPVLVSGLRGHHIIDVACGSGDAHTLAAADDGTVWSWGDGD---YGKLGRGGSDG-CKNPKSI---ERLQGLGVCKVYCGAQFSLALTRDGSVWTWGKGEGFRLGHGTEDHVRHPKLVEALDGKHVVDVSV 234          

Query: 2989 SGKEIIRQISLGKNHALILTESGSLYSAGTNECGQLGIENHVLKQNSFVNKNQCLSIIHPMLIN-------------------IELNSDECIFSIAAGDY----------------------------HSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHGDIDDQFVSKRLIFDFNNSGSGQEFPIELSMGCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKSLVPNLVDRL 3543
            +GK++IR IS G  H+  +T  G LY+ G    G+LG   H   ++  V          P+L++                   +    D  ++S   GDY                            + GA    +   T++  V+TWG G   +LGHG  +D     +L+   +      +  +++S+G  H + LT+ G VYC+G N  GQLG    Q    P LV  L
Sbjct:   67 AGKQVIR-ISCGSTHSAAVTSEGELYTWGRGNYGRLG---HGSSEDQLV----------PVLVSGLRGHHIIDVACGSGDAHTLAAADDGTVWSWGDGDYGKLGRGGSDGCKNPKSIERLQGLGVCKVYCGAQF--SLALTRDGSVWTWGKGEGFRLGHG-TEDHVRHPKLVEALDG-----KHVVDVSVGSIHCLALTDAGEVYCWGRNDQGQLGDIDCQIRPEPTLVSGL 276          

Query: 2932 LGFIKEKSNRILLLPKSIE--SGKEIIRQISLGKNHALILTESGSLYSAGTNECGQLGIENHVLKQNSFVNKNQCLSIIHPMLINIELNSDECIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHGDIDDQFVSKRLIFDFNNSGSGQEFPIELSMGCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKSL-VPNLVDRL---PPAVIHVDTKYFHTVCCTASNEIFTWGIHPNIWQNSLNHEKSHGEISIPESIYTGDLLSNQKIAQISCGTCHASILTDKQFVYCFGSNVWGQLG 3825
            LG I E+   I++ P+  E   GK + R +  G+ H   L E G++Y+ G N+ GQLG E    K    V  +                  + I +++ G+ H+ A+            VF+WG G  GQLG  + ++     R I   ++    Q     ++ G +HS+ L+  G ++ +G N YGQLG+    +S+ VP  +  L   P A I       H+   T S  +F WG +    Q  LN        ++ ++      L +Q++  ISCG  H + LT +  V+ FG+  +GQLG
Sbjct:   14 LGGIDEE---IVVEPRKCEFFHGKRV-RDVGCGRRHTAFLLEDGTVYTCGCNDLGQLGHEKSRKKPEQVVALDA-----------------QIIVALSCGESHTLAL-------NDKGQVFSWGLGSDGQLGLNNFEECIRVPRNIKSLSDVQVAQ-----VACGYWHSLALSKGGHIFSWGQNRYGQLGLGMTGQSISVPQHLQSLQGIPFAQIAAGGA--HSFALTLSGAVFGWGRN-KFGQLGLNDTNDRCFPALLKA------LRSQRVIYISCGEDHTAALTKEGGVFTFGAGGYGQLG 275          

Query: 3283 VFTWGWGVHGQLGHGDIDDQFVSKRLIFDFNNSGSGQEFPIELSMGCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKSLVPNLVDRLPPAVI-HVDTKYFHTVCCTASNEIFTWGIHPNIWQNSLNHEKSHGEISIPESIYTGDLLSNQKIAQISCGTCHASILTDKQFVYCFGSNVWGQLGLGNRKDNKNLVEVNIP--------VPIDFVSSDDGITIAMSKSENSTKLFVWGR 3963
            +  WG   +GQLG G ID++ V +    +F +    ++    +  G  H+  L   G VY  G N  GQLG +  +K   P  V  L   +I  +     HT+      ++F+WG+  +      N E+    I +P +I +   LS+ ++AQ++CG  H+  L+    ++ +G N +GQLGLG    +     +++P        +P   +++    + A++    S  +F WGR
Sbjct:    1 MLCWGNASYGQLGLGGIDEEIVVEPRKCEFFHGKRVRD----VGCGRRHTAFLLEDGTVYTCGCNDLGQLGHEKSRKK--PEQVVALDAQIIVALSCGESHTLALNDKGQVFSWGLGSDGQLGLNNFEEC---IRVPRNIKS---LSDVQVAQVACGYWHSLALSKGGHIFSWGQNRYGQLGLGMTGQS-----ISVPQHLQSLQGIPFAQIAAGGAHSFALTL---SGAVFGWGR 216          

Query: 3256 TSHTTQNSHVFTWGWGVHGQLGHGDIDDQFVSKRLIFDFNNSGSGQEFPIELSMGCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKSL-VPNLVDRLPPA-VIHVDTKYFHTVCCTASNEIFTWGIHPNIWQN---SLNHEKSHGEISIPESIYTGDLLSNQKIAQISCGTCHASILTDKQFVYCFGSNVWGQLGLGNRKDN--KNLVEVNIPVPIDFVSSDDGITIAMSKSENSTKLFVWGRCGHSLIQEHIKN 3999
            T+   ++  V+T G    GQLGH +   +   + +  D        +  + LS G  H++ L +KG V+ +G  S GQLG+   ++ + VP  +  L    V  V   Y+H++  +    IF+WG      QN    L    +   IS+P+ + +   L     AQI+ G  H+  LT    V+ +G N +GQLGL +  D     L++      + ++S  +  T A++K      +F +G  G+  +  +  N
Sbjct:   46 TAFLLEDGTVYTCGCNDLGQLGH-EKSRKKPEQVVALD-------AQIIVALSCGESHTLALNDKGQVFSWGLGSDGQLGLNNFEECIRVPRNIKSLSDVQVAQVACGYWHSLALSKGGHIFSWG------QNRYGQLGLGMTGQSISVPQHLQS---LQGIPFAQIAAGGAHSFALTLSGAVFGWGRNKFGQLGLNDTNDRCFPALLKALRSQRVIYISCGEDHTAALTKEGG---VFTFGAGGYGQLGHNSTN 280          

Query: 2971 LPKSIESGKEI-IRQISLGKNHALILTESGSLYSAGTNECGQLGIENHVLKQNSFVNKNQCLSIIHPMLINIELNSDECI--FSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHGDIDDQ--------FVSKRLIFDFNNSGSGQEFPIELSMGCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKSLVPNLVDRLPPAVI-HVDTKYFHTVCCTASN---EIFTWGIHPNIWQNSLNHEKSHGEISIP 3690
            +P++I+S  ++ + Q++ G  H+L L++ G ++S G N  GQLG+              Q +S+         L S + I    IAAG  HS A+ +S +       VF WG    GQLG  D +D+          S+R+I+              +S G  H+  LT +G V+ FG   YGQLG  +    + P  V  L   V+  +     HT+  T S+   + F  G +  +   S  + KS   +  P
Sbjct:  127 VPRNIKSLSDVQVAQVACGYWHSLALSKGGHIFSWGQNRYGQLGLGM----------TGQSISVPQ------HLQSLQGIPFAQIAAGGAHSFALTLSGA-------VFGWGRNKFGQLGLNDTNDRCFPALLKALRSQRVIY--------------ISCGEDHTAALTKEGGVFTFGAGGYGQLGHNSTNHEVNPRKVFELMGNVVTQIACGRQHTLAFTPSSGKMDSFGLGGNGQLGTRSTCNRKSPAPVKGP 344          

Query: 2932 LGFIKEKSNRILLLPKSIE--SGKEIIRQISLGKNHALILTESGSLYSAGTNECGQLGIENHVLKQNSFVNKNQCLSIIHPMLINIELNSDECIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHGDIDDQFVSKRLIFDFNNSGSGQEFPIELSMGCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKSL-VPNLVDRL---PPAVIHVDTKYFHTVCCTASNEIFTWGIHPNIWQNSLNHEKSHGEISIPESIYTGDLLSNQKIAQISCGTCHASILTDKQFVYCFGSNVWGQLG 3825
            LG I E+   I++ P+  E   GK + R +  G+ H   L E G++Y+ G N+ GQLG E    K    V  +                  + I +++ G+ H+ A+            VF+WG G  GQLG  + ++     R I   ++    Q     ++ G +HS+ L+  G ++ +G N YGQLG+    +S+ VP  +  L   P A I       H+   T S  +F WG +    Q  LN        ++ ++      L +Q++  ISCG  H + LT +  V+ FG+  +GQLG
Sbjct:   14 LGGIDEE---IVVEPRKCEFFHGKRV-RDVGCGRRHTAFLLEDGTVYTCGCNDLGQLGHEKSRKKPEQVVALDA-----------------QIIVALSCGESHTLAL-------NDKGQVFSWGLGSDGQLGLNNFEECIRVPRNIKSLSDVQVAQ-----VACGYWHSLALSKGGHIFSWGQNRYGQLGLGMTGQSISVPQHLQSLQGIPFAQIAAGGA--HSFALTLSGAVFGWGRN-KFGQLGLNDTNDRCFPALLKA------LRSQRVIYISCGEDHTAALTKEGGVFTFGAGGYGQLG 275          

Query: 3283 VFTWGWGVHGQLGHGDIDDQFVSKRLIFDFNNSGSGQEFPIELSMGCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKSLVPNLVDRLPPAVI-HVDTKYFHTVCCTASNEIFTWGIHPNIWQNSLNHEKSHGEISIPESIYTGDLLSNQKIAQISCGTCHASILTDKQFVYCFGSNVWGQLGLGNRKDNKNLVEVNIP--------VPIDFVSSDDGITIAMSKSENSTKLFVWGR 3963
            +  WG   +GQLG G ID++ V +    +F +    ++    +  G  H+  L   G VY  G N  GQLG +  +K   P  V  L   +I  +     HT+      ++F+WG+  +      N E+    I +P +I +   LS+ ++AQ++CG  H+  L+    ++ +G N +GQLGLG    +     +++P        +P   +++    + A++    S  +F WGR
Sbjct:    1 MLCWGNASYGQLGLGGIDEEIVVEPRKCEFFHGKRVRD----VGCGRRHTAFLLEDGTVYTCGCNDLGQLGHEKSRKK--PEQVVALDAQIIVALSCGESHTLALNDKGQVFSWGLGSDGQLGLNNFEEC---IRVPRNIKS---LSDVQVAQVACGYWHSLALSKGGHIFSWGQNRYGQLGLGMTGQS-----ISVPQHLQSLQGIPFAQIAAGGAHSFALTL---SGAVFGWGR 216          

Query: 3256 TSHTTQNSHVFTWGWGVHGQLGHGDIDDQFVSKRLIFDFNNSGSGQEFPIELSMGCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKSL-VPNLVDRLPPA-VIHVDTKYFHTVCCTASNEIFTWGIHPNIWQN---SLNHEKSHGEISIPESIYTGDLLSNQKIAQISCGTCHASILTDKQFVYCFGSNVWGQLGLGNRKDN--KNLVEVNIPVPIDFVSSDDGITIAMSKSENSTKLFVWGRCGHSLIQEHIKN 3999
            T+   ++  V+T G    GQLGH +   +   + +  D        +  + LS G  H++ L +KG V+ +G  S GQLG+   ++ + VP  +  L    V  V   Y+H++  +    IF+WG      QN    L    +   IS+P+ + +   L     AQI+ G  H+  LT    V+ +G N +GQLGL +  D     L++      + ++S  +  T A++K      +F +G  G+  +  +  N
Sbjct:   46 TAFLLEDGTVYTCGCNDLGQLGH-EKSRKKPEQVVALD-------AQIIVALSCGESHTLALNDKGQVFSWGLGSDGQLGLNNFEECIRVPRNIKSLSDVQVAQVACGYWHSLALSKGGHIFSWG------QNRYGQLGLGMTGQSISVPQHLQS---LQGIPFAQIAAGGAHSFALTLSGAVFGWGRNKFGQLGLNDTNDRCFPALLKALRSQRVIYISCGEDHTAALTKEGG---VFTFGAGGYGQLGHNSTN 280          

Query: 2971 LPKSIESGKEI-IRQISLGKNHALILTESGSLYSAGTNECGQLGIENHVLKQNSFVNKNQCLSIIHPMLINIELNSDECI--FSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHGDIDDQ--------FVSKRLIFDFNNSGSGQEFPIELSMGCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKSLVPNLVDRLPPAVI-HVDTKYFHTVCCTASN---EIFTWGIHPNIWQNSLNHEKSHGEISIP 3690
            +P++I+S  ++ + Q++ G  H+L L++ G ++S G N  GQLG+              Q +S+         L S + I    IAAG  HS A+ +S +       VF WG    GQLG  D +D+          S+R+I+              +S G  H+  LT +G V+ FG   YGQLG  +    + P  V  L   V+  +     HT+  T S+   + F  G +  +   S  + KS   +  P
Sbjct:  127 VPRNIKSLSDVQVAQVACGYWHSLALSKGGHIFSWGQNRYGQLGLGM----------TGQSISVPQ------HLQSLQGIPFAQIAAGGAHSFALTLSGA-------VFGWGRNKFGQLGLNDTNDRCFPALLKALRSQRVIY--------------ISCGEDHTAALTKEGGVFTFGAGGYGQLGHNSTNHEVNPRKVFELMGNVVTQIACGRQHTLAFTPSSGKMDSFGLGGNGQLGTRSTCNRKSPAPVKGP 344          

Query: 2959 RILLLPKSIESGKEI-IRQISLGKNHALILTESGSLYSAGTNECGQLGIENHVLKQNSFVNKNQCLSIIHPMLINIELNSDECIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHGDIDDQFVSKRL-IFDFNNSGSGQEFPIELSMGCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKSLVPNLVDRLPPA-VIHVDTKYFHTVCCTASNEIFTWGIHPNIWQNSLNHEK-SHGEISIPESIYTGDLLSNQKIAQISCG-TCH-ASILTDKQF---VYCFGSNVWGQLGLGN 3834
            + L LP+ +E+   I + Q++ G  H + LT+ G +Y+ G N  GQLG+     K+   ++  QC+  +  M +            ++AG  HS A+ VS S       VF WG    GQLG GD  D+     +   +   + S       +S G  H+ ILT  G V+ FG+  +GQLG  + +  L P LV  L  A V  +    +HT+    +N+I+++G +    QN L     SH  + +P  +     +   KI  I  G  C  A + TD++F     C  +N   QL L N
Sbjct:  103 QALYLPRMLEAFCRIPVSQVACGSRHTVALTKEGQVYTWGQNSRGQLGLG----KKGCSISSPQCVRSLSGMPL----------VQVSAGGDHSFALSVSGS-------VFGWGRNDCGQLGLGDSQDRCTPTSVDSLNLKKTTS-------ISCGKDHTAILTKHGTVFTFGSGQFGQLGHNSSRNELRPRLVAELWGAKVTRIACGRYHTLVLQENNKIYSFGCND---QNQLGRSNDSHPSVPLP--VLLPQDIGGTKIRTIFAGENCSFAPLTTDEKFHRDSNCDNANNKAQLCLEN 370          

Query: 3412 SMGCFHS--VILTNKGFVYCFGNNSYGQLGVQTLQKSLVPNLVD---RLPPAVIHVDTKYFHTVCCTASNEIFTWGIHPNIWQNSLNHEKSHGEISIPESIYTGDLLSNQKIAQISCGTCHASILTDKQFVYCFGSNVWGQLGLGNRKDNKNLVEVNIPVPIDFVSSDDGITIAMSKSENS--TKLFVWGRCGHSLIQEHIKNPVSDTLKPQLLIE 4038
            ++GC     ++L+ KG VY           V   Q   +P +++   R+P + +   ++  HTV  T   +++TWG +    +  L   K    IS P+ + +   LS   + Q+S G  H+  L+    V+ +G N  GQLGLG+ +D         P  +D ++     +I+  K   +  TK       G     +   N   + L+P+L+ E
Sbjct:   79 AVGCGDDEVILLSEKGSVY----------RVDVTQALYLPRMLEAFCRIPVSQVACGSR--HTVALTKEGQVYTWGQNS---RGQLGLGKKGCSISSPQCVRS---LSGMPLVQVSAGGDHSFALSVSGSVFGWGRNDCGQLGLGDSQDR------CTPTSVDSLNLKKTTSISCGKDHTAILTKHGTVFTFGSGQFGQLGHNSSRNELRPRLVAE 270          

Query: 2998 EIIRQISLGKNHALILTESGSLYSAGTNECGQLGIENHVLKQNSFVNKNQCLSIIHPMLINIE-LNSDECIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHGDIDDQFVSKRLIFDFNNSGSGQEFPIE-LSMGCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKS--LVPNLVDRLPPAVIHVDTKYFHTVCCTASNEIFTWGIHPNIWQNSLNHEKSHGEISIPESIYTGDLLSNQKIAQISCGTCHASILTDKQFVYCFGSNVWGQLGLG 3831
            E I+ ++ G+NH LI T  G +Y+ G N  GQLG+ +   K +                  +E  +S   I  +AAG   S A+ VS         +F WG    GQ+G G  + Q  S + +      G G+  P+  +S G +HS  +T  G +Y FG    G+LG+ T Q S   VP  V  +  AV  V     HTV  T  + +FT+G+        L H     E  +P  +   +     ++ Q++CG  H +++TD   +Y FG    G+L LG
Sbjct:   88 ERIKLVACGRNHTLICTAKGQVYACGGNSEGQLGLGDWEEKTS---------------FQRVEFFDSQGAIQMLAAGSNTSAALTVS-------GKLFMWGDNSEGQIGLGK-ESQASSPQEV------GVGR--PVSWVSCGYYHSAFVTVDGALYTFGERDSGKLGLGTEQLSGHRVPQRVKSIKEAVKQVACGGGHTVALT-DDAVFTFGLG---QFGQLGHGTFIFESRLPRLV---EHFKKGRVCQVACGENHTAVITDDGLLYTFGDGRHGKLALG 331          

Query: 2998 EIIRQISLGKNHALILTESGSLYSAGTNECGQLGIENHVLKQNSFVNKNQCLSIIHPMLINIELNSDECIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHGDIDDQFVSKRLIFDFNNSGSGQEFPIELSMGCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKSLVPNLVDRLPPAVIHVDTKYFHTVCCTASNEIFTWGIHPNIWQNSLNHEKSHGEISIPESIYTGDLLSN------QKIAQISCGTCHASILTDKQFVYCFGSNVWGQLGLGNRKDNKNLVEVNIPVPIDFVSSDDGITIAMSKSENSTK-------LFVWGRCGH---SLIQEHIKNPVSDTLKPQLL 4032
            ++ R+I+ G  H  ++TE+G L+  G+N  GQLG+ + +      VNK  C+  +    I +          +A G  H       T   T    V+  G    GQLG GD +++   +R+ F F++ G+ Q     L+ G   S  LT  G ++ +G+NS GQ+G+    ++  P  V    P V  V   Y+H+   T    ++T+G            E+  G++ +     +G  +        + + Q++CG  H   LTD   V+ FG   +GQLG G       + E  +P  ++      G    ++  EN T        L+ +G   H   +L +E+  N    TL P+ L
Sbjct:   36 DVPRKIACGDEHTALITENGRLFMFGSNNWGQLGLGSKLT-----VNKPTCVKALKSERIKL----------VACGRNH-------TLICTAKGQVYACGGNSEGQLGLGDWEEKTSFQRVEF-FDSQGAIQ----MLAAGSNTSAALTVSGKLFMWGDNSEGQIGLGKESQASSPQEVGVGRP-VSWVSCGYYHSAFVTVDGALYTFG------------ERDSGKLGLGTEQLSGHRVPQRVKSIKEAVKQVACGGGHTVALTDDA-VFTFGLGQFGQLGHGTF-----IFESRLPRLVEHFKK--GRVCQVACGENHTAVITDDGLLYTFGDGRHGKLALGEENFTNQFKPTLCPRFL 348          

Query: 2965 LLLPKSIESGKEIIRQISL---GKNHALILTESGSLYSAGTNECGQLGIENHVLKQNSFVNKNQCLSIIHPMLINIELNSDECIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHG----DIDDQFVSKRLIFDFNNSGSGQEFPIELSMGCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKSLVPNLVDRL--PPAVIHVDTKYFHTVCCTASNEIFTWGIHPNIWQNSLNHEKSHGEISIPESIYTGDLLSNQKIAQISCGTCHASILTDKQFVYCFGSNVWGQLGLGNRKDNK--NLVEVNIPVPIDFVSSDDGITIAMSKSENSTKLFVWGRC-GHSLIQEHI 3993
            LL P+ +     +IRQ  +     N AL +T +  +++ GTN  G LG+ +               S I P  I++      C   I +  Y +G  VV     T +  VF WG   + QLG+G     +    VS  L+        G+    E++ G  H++ LT  G V+ +G N+ GQ+G  +      P  V        V++V      ++    + EI+ WG + N  Q  L +   +G    P  I     L    + Q++CG  H   LTD+ FVY +G+N +GQLG GN+ +     L+  +    ++  +     T A +K++ S ++ +WG+C G ++   H+
Sbjct:   12 LLPPEELR----LIRQACVFGSAANEALYVTVNDEVFALGTNCSGCLGLGD-------------LQSTIEPRRIDVL-----CGKKIVSLSYGTGPHVVIA---TADGEVFAWGHNGYSQLGNGTTNHGLTPALVSTNLL--------GKRV-TEVACGSHHTIALTADGEVFAWGYNNSGQVGSGSTANQPTPRRVSSCLQSKVVVNVGCGQLCSMAVLDNGEIYGWGYNCN-GQLGLGN---NGNQQTPCRIAA---LQGVNVVQVACGYAHTLALTDEGFVYAWGANSYGQLGTGNKSNQALPTLINTDKERMVEVAACHTSHTSA-AKTQ-SGQVLMWGQCRGQAVSSPHL 323          

Query:  304 MLCILPIGTLMGRIQKKSEYWKPNDVTYLLDKLKSGTFITCMKWWTSYKKKNMCIIGRSDGDLLIIDLENGMTLIEETFPDYIYSIDLLITKDKTLSYCFITTKIQSQWKLLLEEIHEKKDITDSDIGYEFMDFSSYHSHNIINXXXXXXXXXXXQRNPSYLPSKLYQFPQSTFLKSQYVNGKCFLGAYDQISGIYKLFECDNLDSSIYEFQLPLSVVDICVTEDLLYLIIEQVKRRSESNNKNAIFTEPQCLKLCIICRQYAHSRIMEFSPISNKSTDIPLLKCSTASKGFSRSIFVEFELPGVYSKEDILSVINFPVFFNFSCLEKIVPENLFTLTPTQLRENLPNNFRKFSTISSLSKEQLYSKWTVDDIKLIAPIFIISSFDISVCYMSQCFEDKFIDNLLSYNLSKAEWLGVGLKLDMNELYRYTAQLLASGIAHLNNKVTKSRKVLILEYFELASASLQTVLNCISQFWPIEKCLIYFLSQLTQINKMSPTNRVFLSNAIIPMFGHVMSDPLDSFGGIEKRTNKYHEKFRRFIVGNCYFNDLKAAKTMFQFGLLDEAFYIAKEKGCVLELFSFIIENNYNTDWFTCFTEENTIKKYLGFDRDFVLNNLGLVELEIVARSEPKFIKALAEFICDLFMRRSDSTNLFSFHTTMHLCSVFNPYGSIIDTLFRIFASENSVDYLSLRKDSEMSLKSFPQRTSSTESLTDMTAFSETIKIKREIGPLLLTFCLLVISKDNQIDEIQDYLYFIQMFTIIHSANENQXXXXXXXXXXXDKPENRYDSLVNLITLKKNIKQQRNILSKFWSNLMAPKLLFLRDELCISISIMDVDLFEENEKSILIKEKSNKKSEIVKKNSTFSLVESKPSQRCQIKLLGFIKEKSNRILLLPKSIESGKEIIRQISLGKNHALILTESGSLYSAGTNECGQLGIENHVLKQNSFVNKNQCLSIIHPMLINIELNSDECIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHGDIDDQFVSKRLIFDFNNSGSGQEFPIELSMGCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKSLVPNLVDRLPPAVIHVDTKYFHTVCCTASNEIFTWGIHPNIWQNSLNHEKSHGEISIPESIYTGDLLSNQKIAQISCGTCHASILTDKQFVYCFGSNVWGQLGLGNRKDNKNLVEVNIPVPIDFVSSDDGITIAMSKSENSTKLFVWGRCGHSLIQEHIKNPVSDTLKPQLLIEYQHVVDNHLAWKNCFGIDTVVNGIPKIISKKQLMIIFLNFSKYIDRTKFLKVFERLKEYDIISDYYLMNELLIQSLFWRIQSIISRLSMKNNDRLKAIENDIKITFKFYLKLSNYEKYQNLKNPILSMITGFFKQHNLPWDIYEQIIRFLIPTQSFLIATQFTKFSLDVLSSDFLRDLFLNVTSETIHDVVSNDNIKRIELSSNDIDHFYELIRAGNAETIYDAANDHKVVFFSGCNHAFVIGRYREIQLKQIVDKLRKRQLNLSVQMIQRLYNDSSIFPDCLDCLSQKFK 4911
            MLCILPIGTLMGRIQKKSEYWKPNDVTYLLDKLKSGTFITCMKWWTSYKKKNMCIIGRSDGDLLIIDLE+GMTLIEETFPDYIYSIDLLITKDKTLSYCFITTKIQSQWKLLLEEIHEKKDITDSD+GYEFMDFSSYHSHNIINSKAFKKSKKKKQRNPSYLPSKLYQFPQSTFLKSQYVNGKCFLGAYDQISG YKLFECDNLDSSIYEFQLPLSVVDICVTEDLLYLIIEQVKRRSESNNKN+IFTEPQCLKLCIICRQYAHSRIMEFSPISNKSTDIPLLKCSTASKGFSRSIFVEFELPG+YSKEDILSVINFPVFFNFSCLEKIVPENLFTLTPTQLRENLPNNFRKFSTISSLSKEQLYSKWTVDDIKLIAPIFIISSFDISVCYMSQCFEDKFIDNLLSYNLSKAEWLGVGLKLDMNELYRYTAQLLASGIAHLNNKVTKSRKVLILEYFELASASLQTVLNCISQFWPIEKCLIYFLSQLTQINKMSPTNRVFLSNAIIPMFGHVMSDPLDSFGGIEKRTNKYHEKFRRFIVGNCYFNDLKAAKTMFQFGLLDEAFYIAKEKGCVLELFSFIIENNYNTDWFTCFTEENTIKKYLGFDRDFVLNNLGLVELEIVARSEPKFIKALAEFICDLFMRRSDSTNLFSFHTTMHLCSVFNPYGSIIDTLFRIFASENSVDYLSLRKDSEMSLKSFPQRTSSTESLTDMTAFSETIKIKREIGPLLLTFCLLVISKDNQIDEIQDYLYFIQMFTIIHSANENQESSLSSISSELDKPENRYDSLVNLITLKKNIKQQRNILSKFWSNLMAPKLLFLRDELCISISIMDVDLFEENEKSILIKEKSNKKSEIVKKNSTFSLVESKPSQRCQIKLLGFIKEKSNRILLLPKSIESGKEIIRQISLGKNHALILTESGSLYSAGTNECGQLGIENHVLKQNSFVNKNQCLSIIHPMLINIELNSDECIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHGDIDDQFV KRLIFDFNNSGSGQEFPIELSMGCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKSLVPNLVDRLPP VIHVDTKYFHTVCCTASNEIFTWGIHPNIWQNSLNHEKSHGEISIPESIYTGDLLSNQKIAQISCGTCHASILTDKQFVYCFGSNVWGQLGLGNRKDNKNLVEVNIPVPIDFVSSDDGITIAMSKSENSTKLFVWGRCGHSLIQEHIKNPVSDTLKPQLLIEYQHVVDNHLAWKNCFGIDTVVNGIPKIISKKQLMIIFLNFSKYIDRTKFLKVFERLKEYDIISDYYLMNELLIQSLFWRIQSIISRLSMKNNDR KAIENDIKITFKFYLKLSNYEKYQNLKNPILSMITGFFKQHNLPWDIYE+IIRFLIPTQSFLIATQFTKFSLDVLSSDFLRDLFLNVTSETIHDVVSNDNIKRIELSSNDIDHFYELIRAGNAETIYDAANDHKVVFFSGCNHAFVIGRYREIQLKQIVDKLRKRQLNLSVQMIQRLYNDSSIFPDCLDCLSQKFK
Sbjct:    1 MLCILPIGTLMGRIQKKSEYWKPNDVTYLLDKLKSGTFITCMKWWTSYKKKNMCIIGRSDGDLLIIDLESGMTLIEETFPDYIYSIDLLITKDKTLSYCFITTKIQSQWKLLLEEIHEKKDITDSDMGYEFMDFSSYHSHNIINSKAFKKSKKKKQRNPSYLPSKLYQFPQSTFLKSQYVNGKCFLGAYDQISGKYKLFECDNLDSSIYEFQLPLSVVDICVTEDLLYLIIEQVKRRSESNNKNSIFTEPQCLKLCIICRQYAHSRIMEFSPISNKSTDIPLLKCSTASKGFSRSIFVEFELPGLYSKEDILSVINFPVFFNFSCLEKIVPENLFTLTPTQLRENLPNNFRKFSTISSLSKEQLYSKWTVDDIKLIAPIFIISSFDISVCYMSQCFEDKFIDNLLSYNLSKAEWLGVGLKLDMNELYRYTAQLLASGIAHLNNKVTKSRKVLILEYFELASASLQTVLNCISQFWPIEKCLIYFLSQLTQINKMSPTNRVFLSNAIIPMFGHVMSDPLDSFGGIEKRTNKYHEKFRRFIVGNCYFNDLKAAKTMFQFGLLDEAFYIAKEKGCVLELFSFIIENNYNTDWFTCFTEENTIKKYLGFDRDFVLNNLGLVELEIVARSEPKFIKALAEFICDLFMRRSDSTNLFSFHTTMHLCSVFNPYGSIIDTLFRIFASENSVDYLSLRKDSEMSLKSFPQRTSSTESLTDMTAFSETIKIKREIGPLLLTFCLLVISKDNQIDEIQDYLYFIQMFTIIHSANENQESSLSSISSELDKPENRYDSLVNLITLKKNIKQQRNILSKFWSNLMAPKLLFLRDELCISISIMDVDLFEENEKSILIKEKSNKKSEIVKKNSTFSLVESKPSQRCQIKLLGFIKEKSNRILLLPKSIESGKEIIRQISLGKNHALILTESGSLYSAGTNECGQLGIENHVLKQNSFVNKNQCLSIIHPMLINIELNSDECIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHGDIDDQFVPKRLIFDFNNSGSGQEFPIELSMGCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKSLVPNLVDRLPPTVIHVDTKYFHTVCCTASNEIFTWGIHPNIWQNSLNHEKSHGEISIPESIYTGDLLSNQKIAQISCGTCHASILTDKQFVYCFGSNVWGQLGLGNRKDNKNLVEVNIPVPIDFVSSDDGITIAMSKSENSTKLFVWGRCGHSLIQEHIKNPVSDTLKPQLLIEYQHVVDNHLAWKNCFGIDTVVNGIPKIISKKQLMIIFLNFSKYIDRTKFLKVFERLKEYDIISDYYLMNELLIQSLFWRIQSIISRLSMKNNDRFKAIENDIKITFKFYLKLSNYEKYQNLKNPILSMITGFFKQHNLPWDIYEKIIRFLIPTQSFLIATQFTKFSLDVLSSDFLRDLFLNVTSETIHDVVSNDNIKRIELSSNDIDHFYELIRAGNAETIYDAANDHKVVFFSGCNHAFVIGRYREIQLKQIVDKLRKRQLNLSVQMIQRLYNDSSIFPDCLDCLSQKFK 1536          

Query: 2932 LGFIKEKSNRILLLPKSIESGKEIIRQISLGKNHALILTESGSLYSAGTNECGQLGIENHVLKQNSFVNKNQCLSIIHPMLINIELNSDECIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHGDIDDQFVSK--RLIFDFN----NSGSGQEFPIELSMGCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKSLVPNLVDRLPPA-VIHVDTKYFHTVCCTASNEIFTWGI--HPNIWQNSLNHEKSHGEISIPESIYTGDLLSNQKIAQISCGTCHASILTDKQFVYCFGSNVWGQLGLGNRKDN 3846
            LG    +S +  +L   +E    +   ++ G  H L L  +G +Y+ G  E  +LG++  V              ++ P L+   + ++  I  IAAG  HS AI       +++  ++TWG G +G+LGHG+ DDQ   K    +  ++      GSG    + ++      + L     V+ +G+  YG+LG        +P  ++ L  A VI VD     ++  TAS E++TWG   +  +   S NH +       PE +     L+ +KI  ++CG+ H    T+   VY +G N  GQLG G    N
Sbjct: 4195 LGIGSTESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGED---------VLTPTLVKSLVKAE--IIDIAAGGSHSAAI-------SRSGELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWGDGDYGKLGRGGFDICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRK------PEKVAQ---LNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTN 4481          

Query: 2962 ILLLPKSIES-GKEIIRQISL--GKNHALILTESGSLYSAGTNECGQLGIENHVLKQNSFVNKNQCLSIIHPMLINIELNSDECIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHGDIDDQFVSKRLIFDFNNSGSGQEFPIELSMGC--FHSVILTNKGFVYCFGNNSYGQLGVQTLQKSLVPNLVDRLPPA-VIHVDTKYFHTVCCTASNEIFTWGIHPNIWQNSLNHEKSHG-EISIPESIYTGDLLSNQKIAQISCGTCHASILTDKQFVYCFGSNVWGQLGLG 3831
            +++ PK +E+  K  I ++++  G  HA+ LT++G  +S G  + G+LG  N  LK N            +P    I+    + +  +A G  HS AIV          H++TWG G +G+LGHGD      + RL  +   S    +  ++++ G     ++ LT+   V+ +G+  +G+LG       L+P  ++ +  + VI ++     +   T + +++TWG           +   HG +  I E +   D L   KI  ++ G  H   +TD+  VY +G N  GQ G G
Sbjct: 3200 VIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLG-HNSRLKLN------------YPR--KIKYFKGKRVVDVACGSSHSAAIVFG-------GHLYTWGLGDYGRLGHGD-----TAMRLHPELVKSLRDYKV-VQVACGSRDAQTLALTSDFTVWSWGDGDFGKLGRGGSSGCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWG-------KGDYYRLGHGTDKHIREPMQIED-LKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNG 3460          

Query: 2935 GFIKEKSNRILLLPKSIE--SGKEIIRQISLGKNHALILTESGSLYSAGTNECGQLGIENHVLKQNSFVNKNQCLSIIHPMLI-------------------NIELNSDECIFSIAAGDY-------HSGAIVV-------------------STSHTTQNSHVFTWGWGVHGQLGHGDIDDQFVSKRLIFDFNNSGSGQEFPIELSMGCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKSLVPNLVDRL-PPAVIHVDTKYFHTVCCTASN 3606
            G +   S   L  P+ I+   GK ++  ++ G +H+  +   G LY+ G  + G+LG  +  ++             +HP L+                    + L SD  ++S   GD+        SG ++                    S+   T+N  V+TWG G + +LGHG  D        I D   +       + L++G  H + +T++G VY +G+N +GQ G  T+  ++ P LV  L    + HV     H+V  TAS+
Sbjct: 3245 GKLGHNSRLKLNYPRKIKYFKGKRVV-DVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMR-------------LHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWGDGDFGKLGRGGSSGCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHG-TDKHIREPMQIEDLKKTK-----IVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAWTASD 3496          

Query: 2872 KNSTFSLVESKPSQRCQIKLLGFIKEKSNRILLLPKSIESGKEIIRQISLGKNHALILTESGSLYSAGTNECGQLGIENHVLKQNSFVNKNQCLSIIHPMLINIELNSDECIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHGDIDDQFVSKRLIFDFNNSGSGQEFPIELSMGCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKSLVP---NLVDRLPPAVIHVDTKYFHTVCCTASNEIFTWG 3624
            + S F +VE +P +                   LP+ +   K  I++I        +L++ G LY   T+      I+    K N+  ++  CL     +    +L S   +  + A  Y S  + V     T+   V++WG    G+LG GD  D+   +  I D  +    Q    +++ G  HS+ILT  G +Y  G N  GQLG   ++   +P      D +   V  +      ++C +    IFTWG
Sbjct:  434 RESKFEIVEIRPDK-------------------LPRELNE-KFRIKKIVCSGVDTYVLSDCGWLYEVNTS--SDDVIDTFTFKHNAINHQFDCLKNDSVL----KLWSKNRVIDVDANIYSSHVLAV-----TEAGQVYSWGTNTSGKLGQGDTKDR--KRPTIIDTFSRCHLQ--VKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 652          

Query: 3004 IRQISLGKNHALILTESGSLYSAGTNECGQLGIENHVLKQNSF----VNK--NQCLSIIHPMLINI-------------ELNSDECI-FSIAAGDYHSGAIVVSTS----HT---TQNSHVFTWGWGVHGQLGHGDIDDQFVSKRLIFDFNNSGSGQEFPIE-LSMGCFHSVILTNKGFVYCFGNNSYGQLGVQ-TLQKSLVPNLVDRL-PPAVIHVDTKYFHTVCCTASNEIFTWGIHPNIWQNSLNHEKSHGEISIPESIYTGDLLSNQKIAQISCGTCHA-SILTDKQFVYCFGSNVWGQLGL 3828
            I +IS G +H L L ++G LYS G NE  +LG + +  K N       +K  +      H  ++               EL  D+   FSI      +G  +V  +    HT   T+NS +F+WG    GQLG GD  D   + + I + +N       PI+ ++ G   S +LT  GF+Y +G+N+YGQLG   T     +P +V  L    +++V     H    +    +FTWG H    Q  L H     + SIP  +   DLL + K++QI CG  H  + +     VY FG   +GQLG+
Sbjct:  455 IEKISCGFDHTLFLLKNGKLYSCGNNEFKKLGHDCNKFKPNQIQMLDAHKLIDASAGYDHNAVVTDLGLVFTWGKNSFGELGRDKLSDFSIKLVQSLTGHFIVQVACGHDHTLALTKNSEIFSWGANTCGQLGLGDNFDMVSTPQQIKNLSN------LPIKSITAGDKFSFVLTPSGFLYSWGSNNYGQLGRDLTTSYESLPLMVKHLRKQPIVYVSVGQNHVAALSIDGGVFTWG-HGRYGQ--LGHNNFENK-SIPCIVM--DLLGS-KVSQIECGMNHTLAYMVSTGTVYAFGLGKFGQLGI 747          

Query: 3037 LILTESGSLYSAGTNECGQLGIENHVLKQNSFVNKNQCLSIIHPMLINIELNSDECIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHGDIDDQFVSKRLIFDFNNSGSGQEFPIELSMGCFHSVILTNKGFVYCFGNNSYGQLGVQTLQK---SLVPNLVDRLPPAVIHVDTKYFHTVCCTASNEIFTWGIHPNIWQNSLNHEKSHGEISIPESIYTGDLLSNQKIAQISCGTCHASILTDKQFVYCFGSNVWGQLG 3825
            +I+ +  S++S G    GQLGI+       S+  K             I+  S   I  I+ G  H+  ++       +N  +++ G     +LGH D +    ++  + D +         I+ S G  H+ ++T+ G V+ +G NS+G+LG   L      LV +L       ++ V   + HT+  T ++EIF+WG +       L    +   +S P+ I     LSN  I  I+ G   + +LT   F+Y +GSN +GQLG
Sbjct:  412 IIILKMISIFSFGAASYGQLGIDPRNKDYYSYPQK-------------IDKISSSDIEKISCGFDHTLFLL-------KNGKLYSCGNNEFKKLGH-DCNKFKPNQIQMLDAHKL-------IDASAGYDHNAVVTDLGLVFTWGKNSFGELGRDKLSDFSIKLVQSLTGHF---IVQVACGHDHTLALTKNSEIFSWGANTC---GQLGLGDNFDMVSTPQQIKN---LSNLPIKSITAGDKFSFVLTPSGFLYSWGSNNYGQLG 640          

Query: 3283 VFTWGWGVHGQLGHGDIDDQFVSKRLIFDFNNSGSGQEFPIELSMGCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKSLVPNLVDRLPP-AVIHVDTKYFHTVCCTASNEIFTWGIHPNIWQNSLNHEKSHGEISIPE----SIYTGDLLSNQKIAQISCGTCHASILTDKQFVYCFGSNVWGQLGLGNRKDNKNLVEVNIPV------PIDFVSSDDGITIAMSKSENSTKLFVW-----GRCGHSLIQEHIKNPVS-DTLKPQLLIEYQHVVDNHLA 4068
            +F++G   +GQLG    +  + S     D  +S   ++    +S G  H++ L   G +Y  GNN + +LG         PN +  L    +I     Y H    T    +FTWG            + S GE+   +    SI     L+   I Q++CG  H   LT    ++ +G+N  GQLGLG   DN ++V     +      PI  +++ D  +  ++    S  L+ W     G+ G  L   +   P+    L+ Q ++ Y  V  NH+A
Sbjct:  420 IFSFGAASYGQLGIDPRNKDYYSYPQKIDKISSSDIEK----ISCGFDHTLFLLKNGKLYSCGNNEFKKLGHDC--NKFKPNQIQMLDAHKLIDASAGYDHNAVVTDLGLVFTWG------------KNSFGELGRDKLSDFSIKLVQSLTGHFIVQVACGHDHTLALTKNSEIFSWGANTCGQLGLG---DNFDMVSTPQQIKNLSNLPIKSITAGDKFSFVLTP---SGFLYSWGSNNYGQLGRDLTTSYESLPLMVKHLRKQPIV-YVSVGQNHVA 673          

Query: 3004 IRQISLGKNHALILTESGSLYSAGTNECGQLGIENHVLKQNSF--------------VNKNQC---LSIIHPMLINI--ELNSDECI-FSIAAGDYHSGAIVVSTS----HT---TQNSHVFTWGWGVHGQLGHGDIDDQFVSKRLIFDFNNSGSGQEFPIE-LSMGCFHSVILTNKGFVYCFGNNSYGQLGVQ-TLQKSLVPNLVDRL-PPAVIHVDTKYFHTVCCTASNEIFTWGIHPNIWQNSLNHEKSHGEISIPESIYTGDLLSNQKIAQISCGTCHA-SILTDKQFVYCFGSNVWGQLGL 3828
            I +IS G +H L L ++G LYS G NE  +LG + +  K N                 + N     L ++     N   EL  D+   FSI      +G  +V  +    HT   T+NS +F+WG    GQLG GD  D   + + I + +N       PI+ ++ G   S +LT  GF+Y +G+N+YGQLG   T     +P +V  L    +++V     H    +    +FTWG H    Q  L H     + SIP  +   DLL + K++QI CG  H  + +     VY FG   +GQLG+
Sbjct:  171 IEKISCGFDHTLFLLKNGKLYSCGNNEFKKLGHDCNKFKPNQIQMLDAHKLIDASAGYDHNAVVTDLGLVFTWGKNSFGELGRDKLSDFSIKLVQSLTGHFIVQVACGHDHTLALTKNSEIFSWGANTCGQLGLGDNFDMVSTPQQIKNLSN------LPIKSITAGDKFSFVLTPSGFLYSWGSNNYGQLGRDLTTSYESLPLMVKHLRKQPIVYVSVGQNHVAALSIDGGVFTWG-HGRYGQ--LGHNNFENK-SIPCIVM--DLLGS-KVSQIECGMNHTLAYMVSTGTVYAFGLGKFGQLGI 463          

Query: 3037 LILTESGSLYSAGTNECGQLGIENHVLKQNSFVNKNQCLSIIHPMLINIELNSDECIFSIAAGDYHSGAIVVSTSHTTQNSHVFTWGWGVHGQLGHGDIDDQFVSKRLIFDFNNSGSGQEFPIELSMGCFHSVILTNKGFVYCFGNNSYGQLGVQTLQK---SLVPNLVDRLPPAVIHVDTKYFHTVCCTASNEIFTWGIHPNIWQNSLNHEKSHGEISIPESIYTGDLLSNQKIAQISCGTCHASILTDKQFVYCFGSNVWGQLG 3825
            +I+ +  S++S G    GQLGI+       S+  K             I+  S   I  I+ G  H       T    +N  +++ G     +LGH D +    ++  + D +         I+ S G  H+ ++T+ G V+ +G NS+G+LG   L      LV +L       ++ V   + HT+  T ++EIF+WG +       L    +   +S P+ I     LSN  I  I+ G   + +LT   F+Y +GSN +GQLG
Sbjct:  128 IIILKMISIFSFGAASYGQLGIDPRNKDYYSYPQK-------------IDKISSSDIEKISCGFDH-------TLFLLKNGKLYSCGNNEFKKLGH-DCNKFKPNQIQMLDAHKL-------IDASAGYDHNAVVTDLGLVFTWGKNSFGELGRDKLSDFSIKLVQSLTGHF---IVQVACGHDHTLALTKNSEIFSWGANT---CGQLGLGDNFDMVSTPQQIKN---LSNLPIKSITAGDKFSFVLTPSGFLYSWGSNNYGQLG 356          

Query: 3283 VFTWGWGVHGQLGHGDIDDQFVSKRLIFDFNNSGSGQEFPIELSMGCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKSLVPNLVDRLPP-AVIHVDTKYFHTVCCTASNEIFTWGIHPNIWQNSLNHEKSHGEISIPE----SIYTGDLLSNQKIAQISCGTCHASILTDKQFVYCFGSNVWGQLGLGNRKDNKNLVEVNIPV------PIDFVSSDDGITIAMSKSENSTKLFVW-----GRCGHSLIQEHIKNPVSDTLKPQLLIEYQHVVDNHLA 4068
            +F++G   +GQLG    +  + S     D  +S   ++    +S G  H++ L   G +Y  GNN + +LG         PN +  L    +I     Y H    T    +FTWG            + S GE+   +    SI     L+   I Q++CG  H   LT    ++ +G+N  GQLGLG   DN ++V     +      PI  +++ D  +  ++    S  L+ W     G+ G  L   +   P+      +  I Y  V  NH+A
Sbjct:  136 IFSFGAASYGQLGIDPRNKDYYSYPQKIDKISSSDIEK----ISCGFDHTLFLLKNGKLYSCGNNEFKKLGHDC--NKFKPNQIQMLDAHKLIDASAGYDHNAVVTDLGLVFTWG------------KNSFGELGRDKLSDFSIKLVQSLTGHFIVQVACGHDHTLALTKNSEIFSWGANTCGQLGLG---DNFDMVSTPQQIKNLSNLPIKSITAGDKFSFVLTP---SGFLYSWGSNNYGQLGRDLTTSYESLPLMVKHLRKQPIVYVSVGQNHVA 389          

Query: 3004 IRQISLGKNHALILTESGSLYSAGTNECGQLGIENHVLKQNSF--------------VNKNQC---LSIIHPMLINI--ELNSDECI-FSIAAGDYHSGAIVVSTS----HT---TQNSHVFTWGWGVHGQLGHGDIDDQFVSKRLIFDFNNSGSGQEFPIE-LSMGCFHSVILTNKGFVYCFGNNSYGQLGVQ-TLQKSLVPNLVDRL-PPAVIHVDTKYFHTVCCTASNEIFTWGIHPNIWQNSLNHEKSHGEISIPESIYTGDLLSNQKIAQISCGTCHA-SILTDKQFVYCFGSNVWGQLGL 3828
            I +IS G +H L L ++G LYS G NE  +LG + +  K N                 + N     L ++     N   EL  D+   FSI      +G  +V  +    HT   T+NS +F+WG    GQLG GD  D   + + I + +N       PI+ ++ G   S +LT  GF+Y +G+N+YGQLG   T     +P +V  L    +++V     H    +    +FTWG H    Q  L H     + SIP  +   DLL + K++QI CG  H  + +     VY FG   +GQLG+
Sbjct:   39 IEKISCGFDHTLFLLKNGKLYSCGNNEFKKLGHDCNKFKPNQIQMLDAHKLIDASAGYDHNAVVTDLGLVFTWGKNSFGELGRDKLSDFSIKLVQSLTGHFIVQVACGHDHTLALTKNSEIFSWGANTCGQLGLGDNFDMVSTPQQIKNLSN------LPIKSITAGDKFSFVLTPSGFLYSWGSNNYGQLGRDLTTSYESLPLMVKHLRKQPIVYVSVGQNHVAALSIDGGVFTWG-HGRYGQ--LGHNNFENK-SIPCIVM--DLLGS-KVSQIECGMNHTLAYMVSTGTVYAFGLGKFGQLGI 331          

Query: 3283 VFTWGWGVHGQLGHGDIDDQFVSKRLIFDFNNSGSGQEFPIELSMGCFHSVILTNKGFVYCFGNNSYGQLGVQTLQKSLVPNLVDRLPP-AVIHVDTKYFHTVCCTASNEIFTWGIHPNIWQNSLNHEKSHGEISIPE----SIYTGDLLSNQKIAQISCGTCHASILTDKQFVYCFGSNVWGQLGLGNRKDN-------KNLVEVNIPVPIDFVSSDDGITIAMSKSENSTKLFVW-----GRCGHSLIQEHIKNPVSDTLKPQLLIEYQHVVDNHLA 4068
            +F++G   +GQLG    +  + S     D  +S   ++    +S G  H++ L   G +Y  GNN + +LG         PN +  L    +I     Y H    T    +FTWG            + S GE+   +    SI     L+   I Q++CG  H   LT    ++ +G+N  GQLGLG+  D        KNL      +PI  +++ D  +  ++    S  L+ W     G+ G  L   +   P+      +  I Y  V  NH+A
Sbjct:    4 IFSFGAASYGQLGIDPRNKDYYSYPQKIDKISSSDIEK----ISCGFDHTLFLLKNGKLYSCGNNEFKKLGHDC--NKFKPNQIQMLDAHKLIDASAGYDHNAVVTDLGLVFTWG------------KNSFGELGRDKLSDFSIKLVQSLTGHFIVQVACGHDHTLALTKNSEIFSWGANTCGQLGLGDNFDMVSTPQQIKNLSN----LPIKSITAGDKFSFVLTP---SGFLYSWGSNNYGQLGRDLTTSYESLPLMVKHLRKQPIVYVSVGQNHVA 257