E3 ubiquitin-protein ligase TRAF7
Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30017322 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 2
Homology
BLAST of E3 ubiquitin-protein ligase TRAF7 vs. Ensembl Human
Match: MAPKBP1 (mitogen-activated protein kinase binding protein 1 [Source:HGNC Symbol;Acc:HGNC:29536]) HSP 1 Score: 48.1358 bits (113), Expect = 8.825e-7 Identity = 21/61 (34.43%), Postives = 36/61 (59.02%), Query Frame = 1 Query: 1 TGTYNKNIQIFNINTGEHLFSLAGHVAQVNGLCLTSTETHLVSVADDGCINIWELDRKTLI 183 T +KN+ IF+ ++GE + ++ GH V G+ ++ HL+SV+ D CI +W L + I Sbjct: 672 TSCSDKNLSIFDFSSGECVATMFGHSEIVTGMKFSNDCKHLISVSGDSCIFVWRLSSEMTI 732
BLAST of E3 ubiquitin-protein ligase TRAF7 vs. Ensembl Human
Match: MAPKBP1 (mitogen-activated protein kinase binding protein 1 [Source:HGNC Symbol;Acc:HGNC:29536]) HSP 1 Score: 48.1358 bits (113), Expect = 8.918e-7 Identity = 21/61 (34.43%), Postives = 36/61 (59.02%), Query Frame = 1 Query: 1 TGTYNKNIQIFNINTGEHLFSLAGHVAQVNGLCLTSTETHLVSVADDGCINIWELDRKTLI 183 T +KN+ IF+ ++GE + ++ GH V G+ ++ HL+SV+ D CI +W L + I Sbjct: 672 TSCSDKNLSIFDFSSGECVATMFGHSEIVTGMKFSNDCKHLISVSGDSCIFVWRLSSEMTI 732
BLAST of E3 ubiquitin-protein ligase TRAF7 vs. Ensembl Human
Match: MAPKBP1 (mitogen-activated protein kinase binding protein 1 [Source:HGNC Symbol;Acc:HGNC:29536]) HSP 1 Score: 48.1358 bits (113), Expect = 8.919e-7 Identity = 21/61 (34.43%), Postives = 36/61 (59.02%), Query Frame = 1 Query: 1 TGTYNKNIQIFNINTGEHLFSLAGHVAQVNGLCLTSTETHLVSVADDGCINIWELDRKTLI 183 T +KN+ IF+ ++GE + ++ GH V G+ ++ HL+SV+ D CI +W L + I Sbjct: 678 TSCSDKNLSIFDFSSGECVATMFGHSEIVTGMKFSNDCKHLISVSGDSCIFVWRLSSEMTI 738
BLAST of E3 ubiquitin-protein ligase TRAF7 vs. Ensembl Human
Match: PLRG1 (pleiotropic regulator 1 [Source:HGNC Symbol;Acc:HGNC:9089]) HSP 1 Score: 47.3654 bits (111), Expect = 1.125e-6 Identity = 25/101 (24.75%), Postives = 53/101 (52.48%), Query Frame = 1 Query: 1 TGTYNKNIQIFNINTGEHLFSLAGHVAQVNGLCLTSTETHLVSVADDGCINIWELDRKTLIQSINVGSNYCAKAVSIIG-------DVLFICGSDAEIKIY 282 TG+ ++ I+I+++ +G+ SL GH++ V G+ +++ +L S +D + W+L+ +I+ +Y ++ G DVL C D+ +I+ Sbjct: 212 TGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVSTRSPYLFSCGEDKQVKCWDLEYNKVIR------HYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIW 306
BLAST of E3 ubiquitin-protein ligase TRAF7 vs. Ensembl Human
Match: PLRG1 (pleiotropic regulator 1 [Source:HGNC Symbol;Acc:HGNC:9089]) HSP 1 Score: 47.3654 bits (111), Expect = 1.128e-6 Identity = 25/101 (24.75%), Postives = 53/101 (52.48%), Query Frame = 1 Query: 1 TGTYNKNIQIFNINTGEHLFSLAGHVAQVNGLCLTSTETHLVSVADDGCINIWELDRKTLIQSINVGSNYCAKAVSIIG-------DVLFICGSDAEIKIY 282 TG+ ++ I+I+++ +G+ SL GH++ V G+ +++ +L S +D + W+L+ +I+ +Y ++ G DVL C D+ +I+ Sbjct: 221 TGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVSTRSPYLFSCGEDKQVKCWDLEYNKVIR------HYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIW 315
BLAST of E3 ubiquitin-protein ligase TRAF7 vs. Ensembl Celegans
Match: lis-1 (Lissencephaly-1 homolog [Source:UniProtKB/Swiss-Prot;Acc:Q9NDC9]) HSP 1 Score: 54.6842 bits (130), Expect = 1.438e-9 Identity = 29/95 (30.53%), Postives = 51/95 (53.68%), Query Frame = 1 Query: 1 TGTYNKNIQIFNINTGEHLFSLAGHVAQVNGLCLTSTETHLVSVADDGCINIWELDRKTLIQSINVGSNYCAKAVSIIGDVLFICGS-DAEIKIY 282 +G+ +++I+ +NINTG+ LF+L H V GL +L+SVADD + +WEL + +++I ++ + I GS D K++ Sbjct: 307 SGSRDRSIKAWNINTGDVLFTLLAHENWVRGLAFHPKGKYLISVADDKTLRVWELSAQRCMKAIEAHEHFVSTVAFHQTSPFVITGSVDMSCKVW 401
BLAST of E3 ubiquitin-protein ligase TRAF7 vs. Ensembl Fly
Match: Lis-1 (gene:FBgn0015754 transcript:FBtr0087241) HSP 1 Score: 49.6766 bits (117), Expect = 8.373e-8 Identity = 22/71 (30.99%), Postives = 42/71 (59.15%), Query Frame = 1 Query: 1 TGTYNKNIQIFNINTGEHLFSLAGHVAQVNGLCLTSTETHLVSVADDGCINIWELDRKTLIQSINVGSNYC 213 +G+ +K I+I++++ G L +L+GH V GL +LVS +DD I +W+L K ++++ ++C Sbjct: 314 SGSRDKTIRIWDVSVGLCLLTLSGHDNWVRGLAFHPGGKYLVSASDDKTIRVWDLRNKRCMKTLYAHQHFC 384
BLAST of E3 ubiquitin-protein ligase TRAF7 vs. Ensembl Fly
Match: Lis-1 (gene:FBgn0015754 transcript:FBtr0304747) HSP 1 Score: 49.6766 bits (117), Expect = 8.373e-8 Identity = 22/71 (30.99%), Postives = 42/71 (59.15%), Query Frame = 1 Query: 1 TGTYNKNIQIFNINTGEHLFSLAGHVAQVNGLCLTSTETHLVSVADDGCINIWELDRKTLIQSINVGSNYC 213 +G+ +K I+I++++ G L +L+GH V GL +LVS +DD I +W+L K ++++ ++C Sbjct: 314 SGSRDKTIRIWDVSVGLCLLTLSGHDNWVRGLAFHPGGKYLVSASDDKTIRVWDLRNKRCMKTLYAHQHFC 384
BLAST of E3 ubiquitin-protein ligase TRAF7 vs. Ensembl Fly
Match: Lis-1 (gene:FBgn0015754 transcript:FBtr0087240) HSP 1 Score: 49.6766 bits (117), Expect = 8.373e-8 Identity = 22/71 (30.99%), Postives = 42/71 (59.15%), Query Frame = 1 Query: 1 TGTYNKNIQIFNINTGEHLFSLAGHVAQVNGLCLTSTETHLVSVADDGCINIWELDRKTLIQSINVGSNYC 213 +G+ +K I+I++++ G L +L+GH V GL +LVS +DD I +W+L K ++++ ++C Sbjct: 314 SGSRDKTIRIWDVSVGLCLLTLSGHDNWVRGLAFHPGGKYLVSASDDKTIRVWDLRNKRCMKTLYAHQHFC 384
BLAST of E3 ubiquitin-protein ligase TRAF7 vs. Ensembl Fly
Match: Lis-1 (gene:FBgn0015754 transcript:FBtr0087236) HSP 1 Score: 49.6766 bits (117), Expect = 8.373e-8 Identity = 22/71 (30.99%), Postives = 42/71 (59.15%), Query Frame = 1 Query: 1 TGTYNKNIQIFNINTGEHLFSLAGHVAQVNGLCLTSTETHLVSVADDGCINIWELDRKTLIQSINVGSNYC 213 +G+ +K I+I++++ G L +L+GH V GL +LVS +DD I +W+L K ++++ ++C Sbjct: 314 SGSRDKTIRIWDVSVGLCLLTLSGHDNWVRGLAFHPGGKYLVSASDDKTIRVWDLRNKRCMKTLYAHQHFC 384
BLAST of E3 ubiquitin-protein ligase TRAF7 vs. Ensembl Fly
Match: Prp19 (gene:FBgn0261119 transcript:FBtr0086723) HSP 1 Score: 47.7506 bits (112), Expect = 4.034e-7 Identity = 22/93 (23.66%), Postives = 46/93 (49.46%), Query Frame = 1 Query: 1 TGTYNKNIQIFNINTGEHLFSLAGHVAQVNGLCLTSTETHLVSVADDGCINIWELDRKTLIQSINVGSNYCAKAVSI--IGDVLFICGSDAEI 273 TGT + ++I+++ ++ + GH ++ + + +L + ADD C+ +W+L + ++I + Y K + G L I GSD + Sbjct: 367 TGTVDSQVKIWDLKEQSNVANFPGHTGPISAISFSENGYYLATAADDACVKLWDLRKLKNFKTIQLDDGYEVKDLCFDQSGTYLAIAGSDVRV 459
BLAST of E3 ubiquitin-protein ligase TRAF7 vs. Ensembl Zebrafish
Match: mapkbp1 (mitogen-activated protein kinase binding protein 1 [Source:ZFIN;Acc:ZDB-GENE-120207-1]) HSP 1 Score: 48.9062 bits (115), Expect = 3.034e-7 Identity = 22/55 (40.00%), Postives = 33/55 (60.00%), Query Frame = 1 Query: 1 TGTYNKNIQIFNINTGEHLFSLAGHVAQVNGLCLTSTETHLVSVADDGCINIWEL 165 T +KNI IF+ TGE + ++ GH V G+ T+ HL++V+ D CI +W L Sbjct: 678 TSCSDKNISIFDFYTGECVATMFGHSEVVTGMKFTNDCRHLITVSGDSCIFVWRL 732
BLAST of E3 ubiquitin-protein ligase TRAF7 vs. Ensembl Zebrafish
Match: plrg1 (pleiotropic regulator 1 [Source:ZFIN;Acc:ZDB-GENE-040426-2787]) HSP 1 Score: 46.595 bits (109), Expect = 1.354e-6 Identity = 25/96 (26.04%), Postives = 53/96 (55.21%), Query Frame = 1 Query: 1 TGTYNKNIQIFNINTGEHLFSLAGHVAQVNGLCLTSTETHLVSVADDGCINIWELDRKTLIQSI--NVGSNYCAKAVSIIGDVLFICGSDAEIKIY 282 TG+ ++ I+I+++ +G+ SL GH++ V G+ +++ +L S +D + W+L+ +I+ ++ + Y I DVL C DA +++ Sbjct: 212 TGSADRTIKIWDLASGKLKLSLTGHISTVRGVAVSNRSPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYDLDLHPTI-DVLVTCSRDATARVW 306
BLAST of E3 ubiquitin-protein ligase TRAF7 vs. Ensembl Zebrafish
Match: plrg1 (pleiotropic regulator 1 [Source:ZFIN;Acc:ZDB-GENE-040426-2787]) HSP 1 Score: 46.595 bits (109), Expect = 1.356e-6 Identity = 25/96 (26.04%), Postives = 53/96 (55.21%), Query Frame = 1 Query: 1 TGTYNKNIQIFNINTGEHLFSLAGHVAQVNGLCLTSTETHLVSVADDGCINIWELDRKTLIQSI--NVGSNYCAKAVSIIGDVLFICGSDAEIKIY 282 TG+ ++ I+I+++ +G+ SL GH++ V G+ +++ +L S +D + W+L+ +I+ ++ + Y I DVL C DA +++ Sbjct: 218 TGSADRTIKIWDLASGKLKLSLTGHISTVRGVAVSNRSPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYDLDLHPTI-DVLVTCSRDATARVW 312
BLAST of E3 ubiquitin-protein ligase TRAF7 vs. Ensembl Zebrafish
Match: wdr62 (WD repeat domain 62 [Source:ZFIN;Acc:ZDB-GENE-060503-291]) HSP 1 Score: 46.2098 bits (108), Expect = 2.255e-6 Identity = 20/58 (34.48%), Postives = 34/58 (58.62%), Query Frame = 1 Query: 1 TGTYNKNIQIFNINTGEHLFSLAGHVAQVNGLCLTSTETHLVSVADDGCINIWELDRK 174 T +KNI +F+ +GE + +L GH V G+ + HL++V+ D C+ +W LD + Sbjct: 683 TSCSDKNICVFDYESGECVATLFGHSEIVTGMKFSQDCRHLITVSGDSCVFVWRLDSQ 740
BLAST of E3 ubiquitin-protein ligase TRAF7 vs. Ensembl Zebrafish
Match: wdr62 (WD repeat domain 62 [Source:ZFIN;Acc:ZDB-GENE-060503-291]) HSP 1 Score: 46.2098 bits (108), Expect = 2.257e-6 Identity = 20/58 (34.48%), Postives = 34/58 (58.62%), Query Frame = 1 Query: 1 TGTYNKNIQIFNINTGEHLFSLAGHVAQVNGLCLTSTETHLVSVADDGCINIWELDRK 174 T +KNI +F+ +GE + +L GH V G+ + HL++V+ D C+ +W LD + Sbjct: 683 TSCSDKNICVFDYESGECVATLFGHSEIVTGMKFSQDCRHLITVSGDSCVFVWRLDSQ 740
BLAST of E3 ubiquitin-protein ligase TRAF7 vs. Ensembl Xenopus
Match: stam (signal transducing adaptor molecule [Source:Xenbase;Acc:XB-GENE-482429]) HSP 1 Score: 46.9802 bits (110), Expect = 1.771e-6 Identity = 25/101 (24.75%), Postives = 52/101 (51.49%), Query Frame = 1 Query: 1 TGTYNKNIQIFNINTGEHLFSLAGHVAQVNGLCLTSTETHLVSVADDGCINIWELDRKTLIQSINVGSNYCAKAVSIIG-------DVLFICGSDAEIKIY 282 TG+ ++ I+I+++ +G+ SL GH++ V G+ ++ +L S +D + W+L+ +I+ +Y ++ G DVL C D+ +I+ Sbjct: 186 TGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVSGRSPYLFSCGEDKQVKCWDLEYNKVIR------HYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIW 280
BLAST of E3 ubiquitin-protein ligase TRAF7 vs. Ensembl Xenopus
Match: stam (signal transducing adaptor molecule [Source:Xenbase;Acc:XB-GENE-482429]) HSP 1 Score: 46.9802 bits (110), Expect = 1.782e-6 Identity = 25/101 (24.75%), Postives = 52/101 (51.49%), Query Frame = 1 Query: 1 TGTYNKNIQIFNINTGEHLFSLAGHVAQVNGLCLTSTETHLVSVADDGCINIWELDRKTLIQSINVGSNYCAKAVSIIG-------DVLFICGSDAEIKIY 282 TG+ ++ I+I+++ +G+ SL GH++ V G+ ++ +L S +D + W+L+ +I+ +Y ++ G DVL C D+ +I+ Sbjct: 206 TGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVSGRSPYLFSCGEDKQVKCWDLEYNKVIR------HYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIW 300
BLAST of E3 ubiquitin-protein ligase TRAF7 vs. Ensembl Xenopus
Match: stam (signal transducing adaptor molecule [Source:Xenbase;Acc:XB-GENE-482429]) HSP 1 Score: 46.9802 bits (110), Expect = 1.787e-6 Identity = 25/101 (24.75%), Postives = 52/101 (51.49%), Query Frame = 1 Query: 1 TGTYNKNIQIFNINTGEHLFSLAGHVAQVNGLCLTSTETHLVSVADDGCINIWELDRKTLIQSINVGSNYCAKAVSIIG-------DVLFICGSDAEIKIY 282 TG+ ++ I+I+++ +G+ SL GH++ V G+ ++ +L S +D + W+L+ +I+ +Y ++ G DVL C D+ +I+ Sbjct: 214 TGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVSGRSPYLFSCGEDKQVKCWDLEYNKVIR------HYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIW 308
BLAST of E3 ubiquitin-protein ligase TRAF7 vs. Ensembl Xenopus
Match: stam (signal transducing adaptor molecule [Source:Xenbase;Acc:XB-GENE-482429]) HSP 1 Score: 46.9802 bits (110), Expect = 1.792e-6 Identity = 25/101 (24.75%), Postives = 52/101 (51.49%), Query Frame = 1 Query: 1 TGTYNKNIQIFNINTGEHLFSLAGHVAQVNGLCLTSTETHLVSVADDGCINIWELDRKTLIQSINVGSNYCAKAVSIIG-------DVLFICGSDAEIKIY 282 TG+ ++ I+I+++ +G+ SL GH++ V G+ ++ +L S +D + W+L+ +I+ +Y ++ G DVL C D+ +I+ Sbjct: 224 TGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVSGRSPYLFSCGEDKQVKCWDLEYNKVIR------HYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIW 318
BLAST of E3 ubiquitin-protein ligase TRAF7 vs. Ensembl Xenopus
Match: stam (signal transducing adaptor molecule [Source:Xenbase;Acc:XB-GENE-482429]) HSP 1 Score: 46.9802 bits (110), Expect = 1.805e-6 Identity = 25/101 (24.75%), Postives = 52/101 (51.49%), Query Frame = 1 Query: 1 TGTYNKNIQIFNINTGEHLFSLAGHVAQVNGLCLTSTETHLVSVADDGCINIWELDRKTLIQSINVGSNYCAKAVSIIG-------DVLFICGSDAEIKIY 282 TG+ ++ I+I+++ +G+ SL GH++ V G+ ++ +L S +D + W+L+ +I+ +Y ++ G DVL C D+ +I+ Sbjct: 250 TGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVSGRSPYLFSCGEDKQVKCWDLEYNKVIR------HYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIW 344
BLAST of E3 ubiquitin-protein ligase TRAF7 vs. Ensembl Mouse
Match: Mapkbp1 (mitogen-activated protein kinase binding protein 1 [Source:MGI Symbol;Acc:MGI:1347004]) HSP 1 Score: 48.1358 bits (113), Expect = 6.121e-7 Identity = 21/61 (34.43%), Postives = 36/61 (59.02%), Query Frame = 1 Query: 1 TGTYNKNIQIFNINTGEHLFSLAGHVAQVNGLCLTSTETHLVSVADDGCINIWELDRKTLI 183 T +KN+ IF+ ++GE + ++ GH V G+ ++ HL+SV+ D CI +W L + I Sbjct: 673 TSCSDKNLSIFDFSSGECVATMFGHSEIVTGMKFSNDCKHLISVSGDSCIFVWRLSSEMTI 733
BLAST of E3 ubiquitin-protein ligase TRAF7 vs. Ensembl Mouse
Match: Mapkbp1 (mitogen-activated protein kinase binding protein 1 [Source:MGI Symbol;Acc:MGI:1347004]) HSP 1 Score: 48.1358 bits (113), Expect = 6.122e-7 Identity = 21/61 (34.43%), Postives = 36/61 (59.02%), Query Frame = 1 Query: 1 TGTYNKNIQIFNINTGEHLFSLAGHVAQVNGLCLTSTETHLVSVADDGCINIWELDRKTLI 183 T +KN+ IF+ ++GE + ++ GH V G+ ++ HL+SV+ D CI +W L + I Sbjct: 679 TSCSDKNLSIFDFSSGECVATMFGHSEIVTGMKFSNDCKHLISVSGDSCIFVWRLSSEMTI 739
BLAST of E3 ubiquitin-protein ligase TRAF7 vs. Ensembl Mouse
Match: Plrg1 (pleiotropic regulator 1 [Source:MGI Symbol;Acc:MGI:1858197]) HSP 1 Score: 47.3654 bits (111), Expect = 7.350e-7 Identity = 25/101 (24.75%), Postives = 53/101 (52.48%), Query Frame = 1 Query: 1 TGTYNKNIQIFNINTGEHLFSLAGHVAQVNGLCLTSTETHLVSVADDGCINIWELDRKTLIQSINVGSNYCAKAVSIIG-------DVLFICGSDAEIKIY 282 TG+ ++ I+I+++ +G+ SL GH++ V G+ +++ +L S +D + W+L+ +I+ +Y ++ G DVL C D+ +I+ Sbjct: 220 TGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVSTRSPYLFSCGEDKQVKCWDLEYNKVIR------HYHGHLSAVYGLDLHPTLDVLVTCSRDSTARIW 314
BLAST of E3 ubiquitin-protein ligase TRAF7 vs. Ensembl Mouse
Match: Plrg1 (pleiotropic regulator 1 [Source:MGI Symbol;Acc:MGI:1858197]) HSP 1 Score: 47.3654 bits (111), Expect = 7.721e-7 Identity = 25/101 (24.75%), Postives = 53/101 (52.48%), Query Frame = 1 Query: 1 TGTYNKNIQIFNINTGEHLFSLAGHVAQVNGLCLTSTETHLVSVADDGCINIWELDRKTLIQSINVGSNYCAKAVSIIG-------DVLFICGSDAEIKIY 282 TG+ ++ I+I+++ +G+ SL GH++ V G+ +++ +L S +D + W+L+ +I+ +Y ++ G DVL C D+ +I+ Sbjct: 211 TGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVSTRSPYLFSCGEDKQVKCWDLEYNKVIR------HYHGHLSAVYGLDLHPTLDVLVTCSRDSTARIW 305
BLAST of E3 ubiquitin-protein ligase TRAF7 vs. Ensembl Mouse
Match: Plrg1 (pleiotropic regulator 1 [Source:MGI Symbol;Acc:MGI:1858197]) HSP 1 Score: 47.3654 bits (111), Expect = 7.742e-7 Identity = 25/101 (24.75%), Postives = 53/101 (52.48%), Query Frame = 1 Query: 1 TGTYNKNIQIFNINTGEHLFSLAGHVAQVNGLCLTSTETHLVSVADDGCINIWELDRKTLIQSINVGSNYCAKAVSIIG-------DVLFICGSDAEIKIY 282 TG+ ++ I+I+++ +G+ SL GH++ V G+ +++ +L S +D + W+L+ +I+ +Y ++ G DVL C D+ +I+ Sbjct: 220 TGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVSTRSPYLFSCGEDKQVKCWDLEYNKVIR------HYHGHLSAVYGLDLHPTLDVLVTCSRDSTARIW 314
BLAST of E3 ubiquitin-protein ligase TRAF7 vs. UniProt/SwissProt
Match: sp|Q42384|PRL1_ARATH (Protein pleiotropic regulatory locus 1 OS=Arabidopsis thaliana OX=3702 GN=PRL1 PE=1 SV=1) HSP 1 Score: 56.6102 bits (135), Expect = 3.514e-9 Identity = 29/96 (30.21%), Postives = 56/96 (58.33%), Query Frame = 1 Query: 1 TGTYNKNIQIFNINTGEHLFSLAGHVAQVNGLCLTSTETHLVSVADDGCINIWELDRKTLIQSI--NVGSNYCAKAVSIIGDVLFICGSDAEIKIY 282 TG+ ++ I+I+++ TG +L GH+ QV GL +++ T++ S DD + W+L++ +I+S ++ YC A+ DVL G D+ +++ Sbjct: 193 TGSADRTIKIWDVATGVLKLTLTGHIEQVRGLAVSNRHTYMFSAGDDKQVKCWDLEQNKVIRSYHGHLSGVYCL-ALHPTLDVLLTGGRDSVCRVW 287
BLAST of E3 ubiquitin-protein ligase TRAF7 vs. UniProt/SwissProt
Match: sp|Q39190|PRL2_ARATH (Protein pleiotropic regulator PRL2 OS=Arabidopsis thaliana OX=3702 GN=PRL2 PE=2 SV=2) HSP 1 Score: 55.0694 bits (131), Expect = 1.246e-8 Identity = 28/96 (29.17%), Postives = 56/96 (58.33%), Query Frame = 1 Query: 1 TGTYNKNIQIFNINTGEHLFSLAGHVAQVNGLCLTSTETHLVSVADDGCINIWELDRKTLIQSI--NVGSNYCAKAVSIIGDVLFICGSDAEIKIY 282 TG+ ++ I+I+++ TG +L GH+ QV GL +++ T++ S DD + W+L++ +I+S ++ YC A+ DV+ G D+ +++ Sbjct: 187 TGSADRTIKIWDVATGVLKLTLTGHIGQVRGLAVSNRHTYMFSAGDDKQVKCWDLEQNKVIRSYHGHLHGVYCL-ALHPTLDVVLTGGRDSVCRVW 281
BLAST of E3 ubiquitin-protein ligase TRAF7 vs. UniProt/SwissProt
Match: sp|A8XZJ9|LIS1_CAEBR (Lissencephaly-1 homolog OS=Caenorhabditis briggsae OX=6238 GN=lis-1 PE=3 SV=2) HSP 1 Score: 55.0694 bits (131), Expect = 1.370e-8 Identity = 30/95 (31.58%), Postives = 53/95 (55.79%), Query Frame = 1 Query: 1 TGTYNKNIQIFNINTGEHLFSLAGHVAQVNGLCLTSTETHLVSVADDGCINIWELDRKTLIQSINVGSNYCAKAVSIIGDVLFICGS-DAEIKIY 282 +G+ +++I+ +NI+TGE +F+L+ H V GL +LVSVADD + IWEL + +++I ++ + + I GS D K++ Sbjct: 293 SGSRDRSIKAWNISTGEVIFTLSAHENWVRGLAFHPKGKYLVSVADDKMMRIWELSAQRCMKAIEAHEHFVSTVAFHQTNPYVITGSVDMSCKVW 387
BLAST of E3 ubiquitin-protein ligase TRAF7 vs. UniProt/SwissProt
Match: sp|Q9NDC9|LIS1_CAEEL (Lissencephaly-1 homolog OS=Caenorhabditis elegans OX=6239 GN=lis-1 PE=1 SV=1) HSP 1 Score: 54.6842 bits (130), Expect = 1.829e-8 Identity = 29/95 (30.53%), Postives = 51/95 (53.68%), Query Frame = 1 Query: 1 TGTYNKNIQIFNINTGEHLFSLAGHVAQVNGLCLTSTETHLVSVADDGCINIWELDRKTLIQSINVGSNYCAKAVSIIGDVLFICGS-DAEIKIY 282 +G+ +++I+ +NINTG+ LF+L H V GL +L+SVADD + +WEL + +++I ++ + I GS D K++ Sbjct: 307 SGSRDRSIKAWNINTGDVLFTLLAHENWVRGLAFHPKGKYLISVADDKTLRVWELSAQRCMKAIEAHEHFVSTVAFHQTSPFVITGSVDMSCKVW 401
BLAST of E3 ubiquitin-protein ligase TRAF7 vs. UniProt/SwissProt
Match: sp|Q17N69|LIS1_AEDAE (Lissencephaly-1 homolog OS=Aedes aegypti OX=7159 GN=AAEL000770 PE=3 SV=2) HSP 1 Score: 51.9878 bits (123), Expect = 1.528e-7 Identity = 26/95 (27.37%), Postives = 52/95 (54.74%), Query Frame = 1 Query: 1 TGTYNKNIQIFNINTGEHLFSLAGHVAQVNGLCLTSTETHLVSVADDGCINIWELDRKTLIQSINVGSNYCAKAVSIIGDVLFICGS-DAEIKIY 282 +G+ +K I+++++N+G LF+L GH V G+ +++S +DD + IW+L K ++++ S++C I GS D +K++ Sbjct: 312 SGSRDKTIRVWDVNSGLCLFTLVGHDNWVRGIVFHPGGKYMLSASDDKTLRIWDLRNKRCMKTLYAHSHFCTSLDMHKSHPYVISGSVDTTVKVW 406
BLAST of E3 ubiquitin-protein ligase TRAF7 vs. TrEMBL
Match: A0A2C9L330 (Uncharacterized protein OS=Biomphalaria glabrata OX=6526 GN=106068930 PE=4 SV=1) HSP 1 Score: 67.0106 bits (162), Expect = 2.603e-10 Identity = 35/96 (36.46%), Postives = 56/96 (58.33%), Query Frame = 1 Query: 1 TGTYNKNIQIFNINTGEHLFSLAGHVAQVNGLCLTSTETHLVSVADDGCINIWELDRKTLIQSINVGSNYCAKAVSIIGDVLFICGSDAEIKIYRY 288 +GTYN+NI IFNI+T E + +L GH+ V L ++ + L S + D I +W L++ IQ+++ A+++ GD L D EIK++RY Sbjct: 491 SGTYNQNIHIFNIDTHEFVLNLCGHLGTVTTLVISPSGRFLFSASHDSNIQMWGLEKLLPIQTLSRHQG-SVNALTLHGDFLLSGSEDHEIKVFRY 585
BLAST of E3 ubiquitin-protein ligase TRAF7 vs. TrEMBL
Match: A0A1S3I5A2 (E3 ubiquitin-protein ligase TRAF7 OS=Lingula unguis OX=7574 GN=LOC106161133 PE=4 SV=1) HSP 1 Score: 66.6254 bits (161), Expect = 3.044e-10 Identity = 34/98 (34.69%), Postives = 56/98 (57.14%), Query Frame = 1 Query: 4 GTYNKNIQIFNINTGEHLFSLAGHVAQVNGLCLTSTETHLVSVADDGCINIWELDRKTLIQSINVGSNYCAKAVSIIGDVLFICGSDAEIKIYRYDRM 297 GTYN+ +Q+F++N+ EH SL GH+ V GL ++ + L + +DD I +W L+ I S++ A+S+ GD L D EIK++++ M Sbjct: 451 GTYNRCVQLFDVNSYEHTQSLKGHIGCVRGLVVSPSGRFLFTASDDHTIQVWNLENNLPIMSLSRHEG-PVNALSLHGDFLLSGSDDTEIKVFKHFEM 547
BLAST of E3 ubiquitin-protein ligase TRAF7 vs. TrEMBL
Match: A0A2C9L378 (Uncharacterized protein OS=Biomphalaria glabrata OX=6526 GN=106068930 PE=4 SV=1) HSP 1 Score: 66.6254 bits (161), Expect = 3.724e-10 Identity = 35/95 (36.84%), Postives = 55/95 (57.89%), Query Frame = 1 Query: 4 GTYNKNIQIFNINTGEHLFSLAGHVAQVNGLCLTSTETHLVSVADDGCINIWELDRKTLIQSINVGSNYCAKAVSIIGDVLFICGSDAEIKIYRY 288 GTYN+NI IFNI+T E + +L GH+ V L ++ + L S + D I +W L++ IQ+++ A+++ GD L D EIK++RY Sbjct: 489 GTYNQNIHIFNIDTHEFVLNLCGHLGTVTTLVISPSGRFLFSASHDSNIQMWGLEKLLPIQTLSRHQG-SVNALTLHGDFLLSGSEDHEIKVFRY 582
BLAST of E3 ubiquitin-protein ligase TRAF7 vs. TrEMBL
Match: K1RIF0 (E3 ubiquitin-protein ligase TRAF7 OS=Crassostrea gigas OX=29159 GN=CGI_10011877 PE=4 SV=1) HSP 1 Score: 65.855 bits (159), Expect = 7.450e-10 Identity = 36/92 (39.13%), Postives = 53/92 (57.61%), Query Frame = 1 Query: 4 GTYNKNIQIFNINTGEHLFSLAGHVAQVNGLCLTSTETHLVSVADDGCINIWELDRKTLIQSINVGSNYCAKAVSIIGDVLFICGSDAEIKI 279 GTYN+NIQ+FN++ +H+FSL GH+ V L +T + LVS + D I IW L+ IQ+++ + AV + D L D EIK+ Sbjct: 487 GTYNRNIQVFNLSNNQHVFSLRGHIGVVTSLTVTPSGHFLVSSSSDQTIMIWNLENMLPIQTLHRHES-GVNAVILFRDFLLSGSEDNEIKV 577
BLAST of E3 ubiquitin-protein ligase TRAF7 vs. TrEMBL
Match: A0A1S3I5C6 (E3 ubiquitin-protein ligase TRAF7-like isoform X1 OS=Lingula unguis OX=7574 GN=LOC106161152 PE=4 SV=1) HSP 1 Score: 65.4698 bits (158), Expect = 8.032e-10 Identity = 33/98 (33.67%), Postives = 56/98 (57.14%), Query Frame = 1 Query: 4 GTYNKNIQIFNINTGEHLFSLAGHVAQVNGLCLTSTETHLVSVADDGCINIWELDRKTLIQSINVGSNYCAKAVSIIGDVLFICGSDAEIKIYRYDRM 297 GTYN+ +Q+F++N+ EH SL GH+ V GL ++ + L + +DD I +W L+ I S++ A+++ GD L D EIK++++ M Sbjct: 497 GTYNRCVQLFDVNSYEHTQSLKGHIGCVRGLVVSPSGRFLFTASDDHTIQVWNLENNLPIMSLSRHEG-PVNALTLHGDFLLSGSDDTEIKVFKHFEM 593
BLAST of E3 ubiquitin-protein ligase TRAF7 vs. Ensembl Cavefish
Match: mapkbp1 (mitogen-activated protein kinase-binding protein 1 [Source:NCBI gene;Acc:103030470]) HSP 1 Score: 49.6766 bits (117), Expect = 1.059e-7 Identity = 23/62 (37.10%), Postives = 37/62 (59.68%), Query Frame = 1 Query: 1 TGTYNKNIQIFNINTGEHLFSLAGHVAQVNGLCLTSTETHLVSVADDGCINIWELDRKTLIQ 186 T +KNI IF+ +GE + ++ GH V G+ T+ HL+SV+ D CI +W L+ + I+ Sbjct: 672 TSCSDKNISIFDFYSGECVATMFGHSELVTGMKFTNDCKHLISVSGDSCIFVWRLNPELTIK 733
BLAST of E3 ubiquitin-protein ligase TRAF7 vs. Ensembl Cavefish
Match: mapkbp1 (mitogen-activated protein kinase-binding protein 1 [Source:NCBI gene;Acc:103030470]) HSP 1 Score: 49.6766 bits (117), Expect = 1.059e-7 Identity = 23/62 (37.10%), Postives = 37/62 (59.68%), Query Frame = 1 Query: 1 TGTYNKNIQIFNINTGEHLFSLAGHVAQVNGLCLTSTETHLVSVADDGCINIWELDRKTLIQ 186 T +KNI IF+ +GE + ++ GH V G+ T+ HL+SV+ D CI +W L+ + I+ Sbjct: 678 TSCSDKNISIFDFYSGECVATMFGHSELVTGMKFTNDCKHLISVSGDSCIFVWRLNPELTIK 739
BLAST of E3 ubiquitin-protein ligase TRAF7 vs. Ensembl Cavefish
Match: plrg1 (pleiotropic regulator 1 [Source:NCBI gene;Acc:103042237]) HSP 1 Score: 48.1358 bits (113), Expect = 3.766e-7 Identity = 26/96 (27.08%), Postives = 53/96 (55.21%), Query Frame = 1 Query: 1 TGTYNKNIQIFNINTGEHLFSLAGHVAQVNGLCLTSTETHLVSVADDGCINIWELDRKTLIQSI--NVGSNYCAKAVSIIGDVLFICGSDAEIKIY 282 TG+ ++ I+I+++ +G+ SL GH++ V G+ ++S +L S +D + W+L+ +I+ ++ + Y I DVL C DA +++ Sbjct: 202 TGSADRTIKIWDLASGKLKLSLTGHISTVRGVAVSSRSPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYDLDLHPTI-DVLVTCSRDATARVW 296
BLAST of E3 ubiquitin-protein ligase TRAF7 vs. Ensembl Cavefish
Match: plrg1 (pleiotropic regulator 1 [Source:NCBI gene;Acc:103042237]) HSP 1 Score: 48.1358 bits (113), Expect = 3.788e-7 Identity = 26/96 (27.08%), Postives = 53/96 (55.21%), Query Frame = 1 Query: 1 TGTYNKNIQIFNINTGEHLFSLAGHVAQVNGLCLTSTETHLVSVADDGCINIWELDRKTLIQSI--NVGSNYCAKAVSIIGDVLFICGSDAEIKIY 282 TG+ ++ I+I+++ +G+ SL GH++ V G+ ++S +L S +D + W+L+ +I+ ++ + Y I DVL C DA +++ Sbjct: 221 TGSADRTIKIWDLASGKLKLSLTGHISTVRGVAVSSRSPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYDLDLHPTI-DVLVTCSRDATARVW 315
BLAST of E3 ubiquitin-protein ligase TRAF7 vs. Ensembl Cavefish
Match: ENSAMXT00000006286.2 (mitogen-activated protein kinase-binding protein 1-like [Source:NCBI gene;Acc:103025404]) HSP 1 Score: 47.3654 bits (111), Expect = 7.709e-7 Identity = 22/55 (40.00%), Postives = 32/55 (58.18%), Query Frame = 1 Query: 1 TGTYNKNIQIFNINTGEHLFSLAGHVAQVNGLCLTSTETHLVSVADDGCINIWEL 165 T +KNI + + +TGE L ++ GH + + TS HL+SV+ D CI IW L Sbjct: 676 TSCSDKNISLLDFSTGECLATMFGHSEIITSIKFTSDCRHLISVSGDSCIFIWRL 730
BLAST of E3 ubiquitin-protein ligase TRAF7 vs. Ensembl Sea Lamprey
Match: plrg1 (pleiotropic regulator 1 [Source:ZFIN;Acc:ZDB-GENE-040426-2787]) HSP 1 Score: 53.9138 bits (128), Expect = 6.425e-10 Identity = 30/96 (31.25%), Postives = 54/96 (56.25%), Query Frame = 1 Query: 1 TGTYNKNIQIFNINTGEHLFSLAGHVAQVNGLCLTSTETHLVSVADDGCINIWELDRKTLIQSINVGSNYCAKAVSI--IGDVLFICGSDAEIKIY 282 TG+ ++ I+I+ + TG+ SL GH++ V G+ ++S +L S +D I W+L+ +I+ + G A A+ + DVL CG DA +++ Sbjct: 230 TGSADRTIKIWELATGKLKLSLTGHISTVRGVAVSSRSPYLFSCGEDKQIKCWDLEYNKVIRHYH-GHLSAAYALDLHPTIDVLVTCGRDATARVW 324
BLAST of E3 ubiquitin-protein ligase TRAF7 vs. Ensembl Sea Lamprey
Match: mapkbp1 (mitogen-activated protein kinase binding protein 1 [Source:ZFIN;Acc:ZDB-GENE-120207-1]) HSP 1 Score: 43.1282 bits (100), Expect = 4.701e-6 Identity = 20/55 (36.36%), Postives = 31/55 (56.36%), Query Frame = 1 Query: 1 TGTYNKNIQIFNINTGEHLFSLAGHVAQVNGLCLTSTETHLVSVADDGCINIWEL 165 T +KN+ +F+ TGE + S GH V G+ + HL+SV+ D C+ +W L Sbjct: 641 TSCSDKNLTLFDFYTGECVASAFGHSEIVTGMKFSHDCKHLISVSGDSCMFLWRL 695
BLAST of E3 ubiquitin-protein ligase TRAF7 vs. Ensembl Yeast
Match: PRP46 (Member of the NineTeen Complex (NTC); this complex contains Prp19p and stabilizes U6 snRNA in catalytic forms of the spliceosome containing U2, U5, and U6 snRNAs [Source:SGD;Acc:S000006072]) HSP 1 Score: 45.8246 bits (107), Expect = 2.630e-7 Identity = 26/96 (27.08%), Postives = 54/96 (56.25%), Query Frame = 1 Query: 1 TGTYNKNIQIFNINTGEHLFSLAGHVAQVNGLCLTSTETHLVSVADDGCINIWELDRKTLIQSINVGSNYCAKAVSI--IGDVLFICGSDAEIKIY 282 TG+ + ++++++ TG+ +LAGHV V + ++ +L SV++D + W+L++ +I+ G + VSI D++ G D+ IK++ Sbjct: 157 TGSNDTTMKVWDLATGKLKTTLAGHVMTVRDVAVSDRHPYLFSVSEDKTVKCWDLEKNQIIRDY-YGHLSGVRTVSIHPTLDLIATAGRDSVIKLW 251
BLAST of E3 ubiquitin-protein ligase TRAF7 vs. Ensembl Yeast
Match: DIP2 (Nucleolar protein; specifically associated with the U3 snoRNA, part of the large ribonucleoprotein complex known as the small subunit (SSU) processome, required for 18S rRNA biogenesis, part of the active pre-rRNA processing complex [Source:SGD;Acc:S000004119]) HSP 1 Score: 42.3578 bits (98), Expect = 4.784e-6 Identity = 24/97 (24.74%), Postives = 50/97 (51.55%), Query Frame = 1 Query: 1 TGTYNKNIQIFNINTGEHLFSLAGHVAQVNGLCLTSTETHLVSVADDGCINIWELDRKTLIQSINVGSNYCAKAVSIIGDVLFICGSDAEIKIYRYD 291 +G+ + NI ++++ L+ L H + G E L+S + DG I +W+L I++ + C +++ D+L G+D+++KI++ D Sbjct: 138 SGSKDSNIIVWDLVGEVGLYKLRSHKDSITGF-WCQGEDWLISTSKDGMIKLWDLKTHQCIETHIAHTGECW-GLAVKDDLLITTGTDSQVKIWKLD 232
BLAST of E3 ubiquitin-protein ligase TRAF7 vs. Ensembl Nematostella
Match: EDO33344 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SSI1]) HSP 1 Score: 54.299 bits (129), Expect = 1.038e-9 Identity = 28/96 (29.17%), Postives = 54/96 (56.25%), Query Frame = 1 Query: 1 TGTYNKNIQIFNINTGEHLFSLAGHVAQVNGLCLTSTETHLVSVADDGCINIWELDRKTLIQSI--NVGSNYCAKAVSIIGDVLFICGSDAEIKIY 282 TG+ ++ I+I+++ +G+ SL GH++ V GL ++ +L S +D + W+L+ +I+ ++ + Y A I DVL CG DA +++ Sbjct: 226 TGSADRTIKIWDLGSGKLKLSLTGHISTVRGLVVSPRHPYLFSAGEDKLVKCWDLEYNKVIRHYHGHLSAVYDADIHPTI-DVLLTCGRDATTRVW 320
BLAST of E3 ubiquitin-protein ligase TRAF7 vs. Ensembl Nematostella
Match: EDO46331 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RQB4]) HSP 1 Score: 47.3654 bits (111), Expect = 2.273e-7 Identity = 27/95 (28.42%), Postives = 47/95 (49.47%), Query Frame = 1 Query: 1 TGTYNKNIQIFNINTGEHLFSLAGHVAQVNGLCLTST-ETHLVSVADDGCINIWELDRKTLIQSINVGSNYCAKAVSIIGDVLFICGSDAEIKIY 282 T + +K + +++ TG + L GH + VN C + ++VS +DD I +W+ ++ Q+ A A S D +F G D EIK++ Sbjct: 118 TASTDKTVALWDYETGARMKRLKGHTSFVNSCCPSRRGMQYVVSGSDDSTIKLWDTRKRGCAQTFQNVFQVTAVAFSDASDQIFSGGIDNEIKVW 212
BLAST of E3 ubiquitin-protein ligase TRAF7 vs. Ensembl Nematostella
Match: EDO37089 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SGX8]) HSP 1 Score: 46.595 bits (109), Expect = 4.226e-7 Identity = 30/97 (30.93%), Postives = 48/97 (49.48%), Query Frame = 1 Query: 4 GTYNKNIQIFNINTGEHLFSLAGHVAQVNGLCLTSTETHLVSVADDGCINIWELDRKTLIQSINVGSNYCAKAVSIIGDVLFICGSDAEIKIYRYDR 294 GTYN+NI +F++N +H+ +L H V GL ++ L S + D + +W LD +Q+++ V + D+L D EIK R R Sbjct: 409 GTYNQNIHVFDVNGLQHVKALTTHFGTVTGLVVSG--RLLFSASYDTTVQVWNLDTMLPMQTLS-RHEASVNCVVVHKDLLLSGSEDTEIKESRKLR 502
BLAST of E3 ubiquitin-protein ligase TRAF7 vs. Ensembl Nematostella
Match: EDO49767 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RFR6]) HSP 1 Score: 45.8246 bits (107), Expect = 6.643e-7 Identity = 25/96 (26.04%), Postives = 54/96 (56.25%), Query Frame = 1 Query: 1 TGTYNKNIQIFNINTGEHLFSLAGHVAQVNGLCLTSTETHLVSVADDGCINIWELDRKTLIQSINVG--SNYCAKAVSIIGDVLFICGSDAEIKIY 282 + + ++ ++I+N+ T H+ +L GH V +C + + +S ++D + IW+L+ ++S+ VG S+ A AV+ G + G D ++K++ Sbjct: 156 SASQDRTLRIWNLETFAHVSTLRGHSETVYCVCCSPDDKFAISGSEDTMVKIWDLESAKEVRSL-VGHTSDIFAVAVTPDGSKVISSGDDTQVKVW 250 HSP 2 Score: 42.743 bits (99), Expect = 9.430e-6 Identity = 19/56 (33.93%), Postives = 33/56 (58.93%), Query Frame = 1 Query: 1 TGTYNKNIQIFNINTGEHLFSLAGHVAQVNGLCLTSTETHLVSVADDGCINIWELD 168 + +Y+K ++I+++ T + SL GH V G+ +TS LVS + D + IW L+ Sbjct: 114 SSSYDKTVKIWDVETCAFVNSLDGHDGHVRGIAITSDGRRLVSASQDRTLRIWNLE 169
BLAST of E3 ubiquitin-protein ligase TRAF7 vs. Ensembl Nematostella
Match: EDO47404 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RLW2]) HSP 1 Score: 46.2098 bits (108), Expect = 7.483e-7 Identity = 22/94 (23.40%), Postives = 48/94 (51.06%), Query Frame = 1 Query: 1 TGTYNKNIQIFNINTGEHLFSLAGHVAQVNGLCLTSTETHLVSVADDGCINIWELDRKTLIQSINVGSNYCAKAVSIIGDVLFICGSDAEIKIY 282 TGT + I+I+++ ++ GH ++ + + +L + ADD + +W+L + ++IN+ + KA+S ++ + EI+IY Sbjct: 371 TGTSDSIIKIWDLKERTNVAKFPGHSGPISDITFSENGYYLATSADDSVVKLWDLRKLKNFKTINLADRFEVKALSFDQSGTYLAVAGTEIQIY 464
BLAST of E3 ubiquitin-protein ligase TRAF7 vs. Ensembl Medaka
Match: wdr62 (WD repeat-containing protein 62 [Source:NCBI gene;Acc:101162822]) HSP 1 Score: 49.6766 bits (117), Expect = 1.215e-7 Identity = 25/56 (44.64%), Postives = 33/56 (58.93%), Query Frame = 1 Query: 1 TGTYNKNIQIFNINTGEHLFSLAGHVAQVNGLCLTSTETHLVSVADDGCINIWELD 168 T NKNI++F+ TGE + SL GH V L + T LVS + D CI +W+LD Sbjct: 681 TSCSNKNIEVFDYETGECVASLFGHSEAVTCLRFSWDCTRLVSASADSCIFVWKLD 736
BLAST of E3 ubiquitin-protein ligase TRAF7 vs. Ensembl Medaka
Match: plrg1 (pleiotropic regulator 1 [Source:NCBI gene;Acc:101163300]) HSP 1 Score: 48.521 bits (114), Expect = 2.814e-7 Identity = 26/96 (27.08%), Postives = 53/96 (55.21%), Query Frame = 1 Query: 1 TGTYNKNIQIFNINTGEHLFSLAGHVAQVNGLCLTSTETHLVSVADDGCINIWELDRKTLIQSI--NVGSNYCAKAVSIIGDVLFICGSDAEIKIY 282 TG+ ++ I+I+++ +G+ SL GH++ V G+ ++S +L S +D + W+L+ +I+ ++ + Y I DVL C DA +++ Sbjct: 217 TGSADRTIKIWDLASGKLKLSLTGHISTVRGVAVSSRSPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYDLDLHPTI-DVLMTCSRDATARVW 311
BLAST of E3 ubiquitin-protein ligase TRAF7 vs. Ensembl Medaka
Match: mapkbp1 (mitogen-activated protein kinase-binding protein 1 [Source:NCBI gene;Acc:105356884]) HSP 1 Score: 46.2098 bits (108), Expect = 2.033e-6 Identity = 21/62 (33.87%), Postives = 35/62 (56.45%), Query Frame = 1 Query: 1 TGTYNKNIQIFNINTGEHLFSLAGHVAQVNGLCLTSTETHLVSVADDGCINIWELDRKTLIQ 186 T +KNI IF+ +GE + ++ GH + GL + HL++V+ D CI +W L + I+ Sbjct: 679 TSCSDKNISIFDFFSGECVATMFGHSEIITGLKFSGDCKHLITVSGDSCIFVWRLSPEMTIR 740
BLAST of E3 ubiquitin-protein ligase TRAF7 vs. Ensembl Medaka
Match: mapkbp1 (mitogen-activated protein kinase-binding protein 1 [Source:NCBI gene;Acc:105356884]) HSP 1 Score: 46.2098 bits (108), Expect = 2.035e-6 Identity = 21/62 (33.87%), Postives = 35/62 (56.45%), Query Frame = 1 Query: 1 TGTYNKNIQIFNINTGEHLFSLAGHVAQVNGLCLTSTETHLVSVADDGCINIWELDRKTLIQ 186 T +KNI IF+ +GE + ++ GH + GL + HL++V+ D CI +W L + I+ Sbjct: 679 TSCSDKNISIFDFFSGECVATMFGHSEIITGLKFSGDCKHLITVSGDSCIFVWRLSPEMTIR 740
BLAST of E3 ubiquitin-protein ligase TRAF7 vs. Ensembl Medaka
Match: mapkbp1 (mitogen-activated protein kinase-binding protein 1 [Source:NCBI gene;Acc:105356884]) HSP 1 Score: 46.2098 bits (108), Expect = 2.036e-6 Identity = 21/62 (33.87%), Postives = 35/62 (56.45%), Query Frame = 1 Query: 1 TGTYNKNIQIFNINTGEHLFSLAGHVAQVNGLCLTSTETHLVSVADDGCINIWELDRKTLIQ 186 T +KNI IF+ +GE + ++ GH + GL + HL++V+ D CI +W L + I+ Sbjct: 685 TSCSDKNISIFDFFSGECVATMFGHSEIITGLKFSGDCKHLITVSGDSCIFVWRLSPEMTIR 746
BLAST of E3 ubiquitin-protein ligase TRAF7 vs. Planmine SMEST
Match: SMESG000069927.1 (SMESG000069927.1) HSP 1 Score: 208.764 bits (530), Expect = 1.081e-65 Identity = 100/100 (100.00%), Postives = 100/100 (100.00%), Query Frame = 1 Query: 4 GTYNKNIQIFNINTGEHLFSLAGHVAQVNGLCLTSTETHLVSVADDGCINIWELDRKTLIQSINVGSNYCAKAVSIIGDVLFICGSDAEIKIYRYDRMFS 303 GTYNKNIQIFNINTGEHLFSLAGHVAQVNGLCLTSTETHLVSVADDGCINIWELDRKTLIQSINVGSNYCAKAVSIIGDVLFICGSDAEIKIYRYDRMFS Sbjct: 478 GTYNKNIQIFNINTGEHLFSLAGHVAQVNGLCLTSTETHLVSVADDGCINIWELDRKTLIQSINVGSNYCAKAVSIIGDVLFICGSDAEIKIYRYDRMFS 577
BLAST of E3 ubiquitin-protein ligase TRAF7 vs. Planmine SMEST
Match: SMESG000069927.1 (SMESG000069927.1) HSP 1 Score: 208.379 bits (529), Expect = 1.472e-65 Identity = 100/100 (100.00%), Postives = 100/100 (100.00%), Query Frame = 1 Query: 4 GTYNKNIQIFNINTGEHLFSLAGHVAQVNGLCLTSTETHLVSVADDGCINIWELDRKTLIQSINVGSNYCAKAVSIIGDVLFICGSDAEIKIYRYDRMFS 303 GTYNKNIQIFNINTGEHLFSLAGHVAQVNGLCLTSTETHLVSVADDGCINIWELDRKTLIQSINVGSNYCAKAVSIIGDVLFICGSDAEIKIYRYDRMFS Sbjct: 482 GTYNKNIQIFNINTGEHLFSLAGHVAQVNGLCLTSTETHLVSVADDGCINIWELDRKTLIQSINVGSNYCAKAVSIIGDVLFICGSDAEIKIYRYDRMFS 581
BLAST of E3 ubiquitin-protein ligase TRAF7 vs. Planmine SMEST
Match: SMESG000080852.1 (SMESG000080852.1) HSP 1 Score: 54.299 bits (129), Expect = 2.052e-9 Identity = 29/61 (47.54%), Postives = 35/61 (57.38%), Query Frame = 1 Query: 1 TGTY------NKNIQIFNINTGEHLFSLAGHVAQVNGLCLTSTETHLVSVADDGCINIWEL 165 +GTY +K I I N TGE L S+AGH GLC HLVSV+ DGCI +W+L Sbjct: 1123 SGTYIATSGSDKYISILNFATGELLASVAGHSEVAVGLCFLGDLKHLVSVSSDGCIFVWKL 1183 HSP 2 Score: 44.2838 bits (103), Expect = 7.775e-6 Identity = 29/90 (32.22%), Postives = 43/90 (47.78%), Query Frame = 1 Query: 1 TGTYNKN--IQIFNINTGEHLFSLAGHVAQVNGLCLTSTETHLVSVA--DDGCINIWELDRKTLIQSINVGSNYCAKAVSIIGDVLFICG 258 TG K+ ++I+++ T LF +GH +V L + +VSV +D IN+WEL+ T + S V S A A S G G Sbjct: 530 TGESGKSPKVRIWSVETHSQLFEFSGHNYRVGALAFSHNSRFVVSVGSQEDTSINVWELNTNTKMASSKVTSKVIAIAFSEAGQFFVTVG 619
BLAST of E3 ubiquitin-protein ligase TRAF7 vs. Planmine SMEST
Match: SMESG000080852.1 (SMESG000080852.1) HSP 1 Score: 54.299 bits (129), Expect = 2.090e-9 Identity = 29/61 (47.54%), Postives = 35/61 (57.38%), Query Frame = 1 Query: 1 TGTY------NKNIQIFNINTGEHLFSLAGHVAQVNGLCLTSTETHLVSVADDGCINIWEL 165 +GTY +K I I N TGE L S+AGH GLC HLVSV+ DGCI +W+L Sbjct: 1092 SGTYIATSGSDKYISILNFATGELLASVAGHSEVAVGLCFLGDLKHLVSVSSDGCIFVWKL 1152 HSP 2 Score: 44.2838 bits (103), Expect = 7.695e-6 Identity = 29/90 (32.22%), Postives = 43/90 (47.78%), Query Frame = 1 Query: 1 TGTYNKN--IQIFNINTGEHLFSLAGHVAQVNGLCLTSTETHLVSVA--DDGCINIWELDRKTLIQSINVGSNYCAKAVSIIGDVLFICG 258 TG K+ ++I+++ T LF +GH +V L + +VSV +D IN+WEL+ T + S V S A A S G G Sbjct: 499 TGESGKSPKVRIWSVETHSQLFEFSGHNYRVGALAFSHNSRFVVSVGSQEDTSINVWELNTNTKMASSKVTSKVIAIAFSEAGQFFVTVG 588
BLAST of E3 ubiquitin-protein ligase TRAF7 vs. Planmine SMEST
Match: SMESG000080852.1 (SMESG000080852.1) HSP 1 Score: 54.299 bits (129), Expect = 2.094e-9 Identity = 29/61 (47.54%), Postives = 35/61 (57.38%), Query Frame = 1 Query: 1 TGTY------NKNIQIFNINTGEHLFSLAGHVAQVNGLCLTSTETHLVSVADDGCINIWEL 165 +GTY +K I I N TGE L S+AGH GLC HLVSV+ DGCI +W+L Sbjct: 1160 SGTYIATSGSDKYISILNFATGELLASVAGHSEVAVGLCFLGDLKHLVSVSSDGCIFVWKL 1220 HSP 2 Score: 44.2838 bits (103), Expect = 7.707e-6 Identity = 29/90 (32.22%), Postives = 43/90 (47.78%), Query Frame = 1 Query: 1 TGTYNKN--IQIFNINTGEHLFSLAGHVAQVNGLCLTSTETHLVSVA--DDGCINIWELDRKTLIQSINVGSNYCAKAVSIIGDVLFICG 258 TG K+ ++I+++ T LF +GH +V L + +VSV +D IN+WEL+ T + S V S A A S G G Sbjct: 567 TGESGKSPKVRIWSVETHSQLFEFSGHNYRVGALAFSHNSRFVVSVGSQEDTSINVWELNTNTKMASSKVTSKVIAIAFSEAGQFFVTVG 656 The following BLAST results are available for this feature:
BLAST of E3 ubiquitin-protein ligase TRAF7 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of E3 ubiquitin-protein ligase TRAF7 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 1
BLAST of E3 ubiquitin-protein ligase TRAF7 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of E3 ubiquitin-protein ligase TRAF7 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of E3 ubiquitin-protein ligase TRAF7 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of E3 ubiquitin-protein ligase TRAF7 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of E3 ubiquitin-protein ligase TRAF7 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of E3 ubiquitin-protein ligase TRAF7 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of E3 ubiquitin-protein ligase TRAF7 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of E3 ubiquitin-protein ligase TRAF7 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 2
BLAST of E3 ubiquitin-protein ligase TRAF7 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 2
BLAST of E3 ubiquitin-protein ligase TRAF7 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of E3 ubiquitin-protein ligase TRAF7 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of E3 ubiquitin-protein ligase TRAF7 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30017322 ID=SMED30017322|Name=E3 ubiquitin-protein ligase TRAF7|organism=Schmidtea mediterranea sexual|type=transcript|length=378bpback to top protein sequence of SMED30017322-orf-1 >SMED30017322-orf-1 ID=SMED30017322-orf-1|Name=SMED30017322-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=102bp TGTYNKNIQIFNINTGEHLFSLAGHVAQVNGLCLTSTETHLVSVADDGCIback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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