c-SKI_SMAD_bind domain-containing protein

Overview


Name	c-SKI_SMAD_bind domain-containing protein
Smed ID	SMED30017315
Length (bp)	1314

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of c-SKI_SMAD_bind domain-containing protein (SMED30017315) t-SNE clustered cells

Violin plots show distribution of expression levels for c-SKI_SMAD_bind domain-containing protein (SMED30017315) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of c-SKI_SMAD_bind domain-containing protein (SMED30017315) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for c-SKI_SMAD_bind domain-containing protein (SMED30017315) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30017315

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 5

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
head region	SMED30017315	h1SMcG0000207	SmedASXL_004727	SmedAsxl_ww_GCZZ01	PMID:27034770 Currie et al., 2016
nervous system	SMED30017315	h1SMcG0000207	dd_Smed_v4_19617_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30017315	h1SMcG0000207	dd_Smed_v4_19617_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
non-ciliated neuron	SMED30017315	h1SMcG0000207	dd_Smed_v4_19617_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
head region	SMED30017315	h1SMcG0000207	dd_Smed_v6_19617_0_1	dd_Smed_v6	PMID:28171748 Stückemann et al., 2017

Note: Hover over icons to view figure legend

Homology

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BLAST of c-SKI_SMAD_bind domain-containing protein vs. Ensembl Human
Match: SKI (SKI proto-oncogene [Source:HGNC Symbol;Acc:HGNC:10896])

HSP 1 Score: 114.775 bits (286), Expect = 9.504e-27
Identity = 63/210 (30.00%), Postives = 98/210 (46.67%), Query Frame = 3

Query:   90 TELENHFLISFANGSNIKILMPHLIRSFFQDIDYPTINQLLTFLSIKCCQCTPEQLRILHTTKILSSDVNQCGLIDKVDAKRLCKFIHNTNL------TSIRSTSSLFV------IPIIHYCFGRQQAFLYPDLYVKSNSRCIKCASCSQIFTTCEFVKHTHLKINHINTVHWGFHSLNWRYFIYIYIFNADVEYHKNATLILDNIKSAF 683
            T LE   +  F  G   ++ +P ++ S  +D     IN +   L I C +CT +QL IL    IL      CGLI K DA+RLC  +             + ++ +L +      + + H CFG+ +  L P+LY   ++ CI+C  C  ++   +FV H+H  + +  T HWGF S NWR +I +       E        LD++K  F
Sbjct:  103 TVLEGETISCFVVGGEKRLCLPQILNSVLRDFSLQQINAVCDELHIYCSRCTADQLEILKVMGILPFSAPSCGLITKTDAERLCNALLYGGAYPPPCKKELAASLALGLELSERSVRVYHECFGKCKGLLVPELYSSPSAACIQCLDCRLMYPPHKFVVHSHKALEN-RTCHWGFDSANWRAYILLSQDYTGKEEQARLGRCLDDVKEKF 311

[Close]

BLAST of c-SKI_SMAD_bind domain-containing protein vs. Ensembl Human
Match: SKIL (SKI like proto-oncogene [Source:HGNC Symbol;Acc:HGNC:10897])

HSP 1 Score: 110.153 bits (274), Expect = 2.916e-25
Identity = 65/223 (29.15%), Postives = 101/223 (45.29%), Query Frame = 3

Query:   90 TELENHFLISFANGSNIKILMPHLIRSFFQDIDYPTINQLLTFLSIKCCQCTPEQLRILHTTKILSSDVNQCGLIDKVDAKRLC-------KFIHN-------TNLTSIRSTSSLFVIPIIHYCFGRQQAFLYPDLYVKSNSRCIKCASCSQIFTTCEFVKHTHLKINHINTVHWGFHSLNWRYFIYIYIFNADVEYHKNATLILDNIKSAFLKEDMKKMKNK 716
            T LE   +  F  G   ++ +P ++ S  ++     IN +   L I C +CT +QL IL    IL  +   CGLI   DA+RLC        F  N       ++L  ++ T S F +   H C G+ Q    P  YV+ ++ CI+C  C  +F    FV H+H   +   T HWGF S  W  ++++          K   +IL+ +K  F     K+ ++K
Sbjct:  147 TVLEGESISCFQVGGEKRLCLPQVLNSVLREFTLQQINTVCDELYIYCSRCTSDQLHILKVLGILPFNAPSCGLITLTDAQRLCNALLRPRTFPQNGSVLPAKSSLAQLKETGSAFEVE--HECLGKCQGLFAPQFYVQPDAPCIQCLECCGMFAPQTFVMHSHRSPDK-RTCHWGFESAKWHCYLHVNQKYLGTPEEKKLKIILEEMKEKFSMRSGKRNQSK 366

[Close]

Query:   90 TELENHFLISFANGSNIKILMPHLIRSFFQDIDYPTINQLLTFLSIKCCQCTPEQLRILHTTKILSSDVNQCGLIDKVDAKRLC-------KFIHN-------TNLTSIRSTSSLFVIPIIHYCFGRQQAFLYPDLYVKSNSRCIKCASCSQIFTTCEFVKHTHLKINHINTVHWGFHSLNWRYFIYIYIFNADVEYHKNATLILDNIKSAFLKEDMKKMKNK 716
            T LE   +  F  G   ++ +P ++ S  ++     IN +   L I C +CT +QL IL    IL  +   CGLI   DA+RLC        F  N       ++L  ++ T S F +   H C G+ Q    P  YV+ ++ CI+C  C  +F    FV H+H   +   T HWGF S  W  ++++          K   +IL+ +K  F     K+ ++K
Sbjct:  147 TVLEGESISCFQVGGEKRLCLPQVLNSVLREFTLQQINTVCDELYIYCSRCTSDQLHILKVLGILPFNAPSCGLITLTDAQRLCNALLRPRTFPQNGSVLPAKSSLAQLKETGSAFEVE--HECLGKCQGLFAPQFYVQPDAPCIQCLECCGMFAPQTFVMHSHRSPDK-RTCHWGFESAKWHCYLHVNQKYLGTPEEKKLKIILEEMKEKFSMRSGKRNQSK 366

[Close]

BLAST of c-SKI_SMAD_bind domain-containing protein vs. Ensembl Human
Match: SKIL (SKI like proto-oncogene [Source:HGNC Symbol;Acc:HGNC:10897])

HSP 1 Score: 110.153 bits (274), Expect = 2.982e-25
Identity = 65/223 (29.15%), Postives = 101/223 (45.29%), Query Frame = 3

Query:   90 TELENHFLISFANGSNIKILMPHLIRSFFQDIDYPTINQLLTFLSIKCCQCTPEQLRILHTTKILSSDVNQCGLIDKVDAKRLC-------KFIHN-------TNLTSIRSTSSLFVIPIIHYCFGRQQAFLYPDLYVKSNSRCIKCASCSQIFTTCEFVKHTHLKINHINTVHWGFHSLNWRYFIYIYIFNADVEYHKNATLILDNIKSAFLKEDMKKMKNK 716
            T LE   +  F  G   ++ +P ++ S  ++     IN +   L I C +CT +QL IL    IL  +   CGLI   DA+RLC        F  N       ++L  ++ T S F +   H C G+ Q    P  YV+ ++ CI+C  C  +F    FV H+H   +   T HWGF S  W  ++++          K   +IL+ +K  F     K+ ++K
Sbjct:  147 TVLEGESISCFQVGGEKRLCLPQVLNSVLREFTLQQINTVCDELYIYCSRCTSDQLHILKVLGILPFNAPSCGLITLTDAQRLCNALLRPRTFPQNGSVLPAKSSLAQLKETGSAFEVE--HECLGKCQGLFAPQFYVQPDAPCIQCLECCGMFAPQTFVMHSHRSPDK-RTCHWGFESAKWHCYLHVNQKYLGTPEEKKLKIILEEMKEKFSMRSGKRNQSK 366

[Close]

BLAST of c-SKI_SMAD_bind domain-containing protein vs. Ensembl Human
Match: SKIL (SKI like proto-oncogene [Source:HGNC Symbol;Acc:HGNC:10897])

HSP 1 Score: 110.153 bits (274), Expect = 3.175e-25
Identity = 65/223 (29.15%), Postives = 101/223 (45.29%), Query Frame = 3

Query:   90 TELENHFLISFANGSNIKILMPHLIRSFFQDIDYPTINQLLTFLSIKCCQCTPEQLRILHTTKILSSDVNQCGLIDKVDAKRLC-------KFIHN-------TNLTSIRSTSSLFVIPIIHYCFGRQQAFLYPDLYVKSNSRCIKCASCSQIFTTCEFVKHTHLKINHINTVHWGFHSLNWRYFIYIYIFNADVEYHKNATLILDNIKSAFLKEDMKKMKNK 716
            T LE   +  F  G   ++ +P ++ S  ++     IN +   L I C +CT +QL IL    IL  +   CGLI   DA+RLC        F  N       ++L  ++ T S F +   H C G+ Q    P  YV+ ++ CI+C  C  +F    FV H+H   +   T HWGF S  W  ++++          K   +IL+ +K  F     K+ ++K
Sbjct:  127 TVLEGESISCFQVGGEKRLCLPQVLNSVLREFTLQQINTVCDELYIYCSRCTSDQLHILKVLGILPFNAPSCGLITLTDAQRLCNALLRPRTFPQNGSVLPAKSSLAQLKETGSAFEVE--HECLGKCQGLFAPQFYVQPDAPCIQCLECCGMFAPQTFVMHSHRSPDK-RTCHWGFESAKWHCYLHVNQKYLGTPEEKKLKIILEEMKEKFSMRSGKRNQSK 346

[Close]

BLAST of c-SKI_SMAD_bind domain-containing protein vs. Ensembl Fly
Match: Snoo (gene:FBgn0085450 transcript:FBtr0343409)

HSP 1 Score: 130.183 bits (326), Expect = 4.889e-32
Identity = 76/216 (35.19%), Postives = 109/216 (50.46%), Query Frame = 3

Query:   90 TELENHFLISFANGSNIKILMPHLIRSFFQDIDYPTINQLLTFLSIKCCQCTPEQLRILHTTKILSSDVNQCGLIDKVDAKRLC-KFIHNTNLTSIRSTSSL----FVIPIIHYCFGRQQAFLYPDLYVKSNSRCIKCASCSQIFTTCEFVKHTHLKI-NHINTVHWGFHSLNWRYFIYIYIFNADVEYHKNATLILDNIKSAFLKEDMKKMKNKL 719
            T+LE   +  F+ G  +++ +P  + +   D     IN++   L I C QCT +QL      KIL SDV   GLI + DA+RLC   +H ++  S     SL        + H CFG+ +    PD+Y      CIKC  C   F+  +FV H H K  NH  T HWGF S NW  ++++ +   DVE  +   +ILD +K   LKE M K + +L
Sbjct:  119 TKLEGKTIGCFSVGGEMRLCLPQFLNNVLNDFSLEQINRIFDELGIYCSQCTHDQLVEFKAAKILPSDVKASGLITRTDAERLCAALLHRSDRNSYVPIESLAKGALSFHVYHKCFGKCEGICTPDMYSYQKPTCIKCLECDGWFSPQKFVGHVHRKFENH--TCHWGFDSRNWHDYLHVAL---DVENREKYQIILDQLKEVELKE-MHKAQREL 328

[Close]

BLAST of c-SKI_SMAD_bind domain-containing protein vs. Ensembl Fly
Match: Snoo (gene:FBgn0085450 transcript:FBtr0112717)

HSP 1 Score: 130.183 bits (326), Expect = 4.889e-32
Identity = 76/216 (35.19%), Postives = 109/216 (50.46%), Query Frame = 3

Query:   90 TELENHFLISFANGSNIKILMPHLIRSFFQDIDYPTINQLLTFLSIKCCQCTPEQLRILHTTKILSSDVNQCGLIDKVDAKRLC-KFIHNTNLTSIRSTSSL----FVIPIIHYCFGRQQAFLYPDLYVKSNSRCIKCASCSQIFTTCEFVKHTHLKI-NHINTVHWGFHSLNWRYFIYIYIFNADVEYHKNATLILDNIKSAFLKEDMKKMKNKL 719
            T+LE   +  F+ G  +++ +P  + +   D     IN++   L I C QCT +QL      KIL SDV   GLI + DA+RLC   +H ++  S     SL        + H CFG+ +    PD+Y      CIKC  C   F+  +FV H H K  NH  T HWGF S NW  ++++ +   DVE  +   +ILD +K   LKE M K + +L
Sbjct:  119 TKLEGKTIGCFSVGGEMRLCLPQFLNNVLNDFSLEQINRIFDELGIYCSQCTHDQLVEFKAAKILPSDVKASGLITRTDAERLCAALLHRSDRNSYVPIESLAKGALSFHVYHKCFGKCEGICTPDMYSYQKPTCIKCLECDGWFSPQKFVGHVHRKFENH--TCHWGFDSRNWHDYLHVAL---DVENREKYQIILDQLKEVELKE-MHKAQREL 328

[Close]

BLAST of c-SKI_SMAD_bind domain-containing protein vs. Ensembl Fly
Match: Snoo (gene:FBgn0085450 transcript:FBtr0112719)

HSP 1 Score: 130.183 bits (326), Expect = 4.889e-32
Identity = 76/216 (35.19%), Postives = 109/216 (50.46%), Query Frame = 3

Query:   90 TELENHFLISFANGSNIKILMPHLIRSFFQDIDYPTINQLLTFLSIKCCQCTPEQLRILHTTKILSSDVNQCGLIDKVDAKRLC-KFIHNTNLTSIRSTSSL----FVIPIIHYCFGRQQAFLYPDLYVKSNSRCIKCASCSQIFTTCEFVKHTHLKI-NHINTVHWGFHSLNWRYFIYIYIFNADVEYHKNATLILDNIKSAFLKEDMKKMKNKL 719
            T+LE   +  F+ G  +++ +P  + +   D     IN++   L I C QCT +QL      KIL SDV   GLI + DA+RLC   +H ++  S     SL        + H CFG+ +    PD+Y      CIKC  C   F+  +FV H H K  NH  T HWGF S NW  ++++ +   DVE  +   +ILD +K   LKE M K + +L
Sbjct:  119 TKLEGKTIGCFSVGGEMRLCLPQFLNNVLNDFSLEQINRIFDELGIYCSQCTHDQLVEFKAAKILPSDVKASGLITRTDAERLCAALLHRSDRNSYVPIESLAKGALSFHVYHKCFGKCEGICTPDMYSYQKPTCIKCLECDGWFSPQKFVGHVHRKFENH--TCHWGFDSRNWHDYLHVAL---DVENREKYQIILDQLKEVELKE-MHKAQREL 328

[Close]

BLAST of c-SKI_SMAD_bind domain-containing protein vs. Ensembl Fly
Match: Snoo (gene:FBgn0085450 transcript:FBtr0112718)

HSP 1 Score: 130.183 bits (326), Expect = 4.889e-32
Identity = 76/216 (35.19%), Postives = 109/216 (50.46%), Query Frame = 3

Query:   90 TELENHFLISFANGSNIKILMPHLIRSFFQDIDYPTINQLLTFLSIKCCQCTPEQLRILHTTKILSSDVNQCGLIDKVDAKRLC-KFIHNTNLTSIRSTSSL----FVIPIIHYCFGRQQAFLYPDLYVKSNSRCIKCASCSQIFTTCEFVKHTHLKI-NHINTVHWGFHSLNWRYFIYIYIFNADVEYHKNATLILDNIKSAFLKEDMKKMKNKL 719
            T+LE   +  F+ G  +++ +P  + +   D     IN++   L I C QCT +QL      KIL SDV   GLI + DA+RLC   +H ++  S     SL        + H CFG+ +    PD+Y      CIKC  C   F+  +FV H H K  NH  T HWGF S NW  ++++ +   DVE  +   +ILD +K   LKE M K + +L
Sbjct:  119 TKLEGKTIGCFSVGGEMRLCLPQFLNNVLNDFSLEQINRIFDELGIYCSQCTHDQLVEFKAAKILPSDVKASGLITRTDAERLCAALLHRSDRNSYVPIESLAKGALSFHVYHKCFGKCEGICTPDMYSYQKPTCIKCLECDGWFSPQKFVGHVHRKFENH--TCHWGFDSRNWHDYLHVAL---DVENREKYQIILDQLKEVELKE-MHKAQREL 328

[Close]

BLAST of c-SKI_SMAD_bind domain-containing protein vs. Ensembl Fly
Match: fuss (gene:FBgn0039932 transcript:FBtr0301336)

HSP 1 Score: 70.8626 bits (172), Expect = 1.099e-12
Identity = 42/134 (31.34%), Postives = 66/134 (49.25%), Query Frame = 3

Query:  141 KILMPHLIRSFFQDIDYPTINQLLTFLSIKCCQCTPEQLRILHTTKILSSDVNQCGLIDKVDAKRLCKFIHNTNLTSIRSTSSLFVIPIIHYC-FGRQQAFLYPDLYVKSNSRCIKCASCSQIFTTCEFVKHTH 539
            ++ +  +  +  +   Y  I+     L I C QCTP QL IL     +     +CG+I + +A+RLCK     N T  R     F   + H C +G + +FL P  Y  S ++CIKC+ C   F+  +F+ H+H
Sbjct:   46 RLCLAQISNTLLKQFSYNEIHNRRVALGITCVQCTPVQLEILRRAGAMPVSSRRCGMITRREAERLCKSFLGDN-TPPRLPDD-FAFNVQHKCAWGCRGSFL-PSRYNSSRAKCIKCSYCGMFFSPNKFIFHSH 176

[Close]

BLAST of c-SKI_SMAD_bind domain-containing protein vs. Ensembl Zebrafish
Match: skia (v-ski avian sarcoma viral oncogene homolog a [Source:ZFIN;Acc:ZDB-GENE-990715-9])

HSP 1 Score: 121.324 bits (303), Expect = 3.599e-29
Identity = 66/208 (31.73%), Postives = 96/208 (46.15%), Query Frame = 3

Query:   90 TELENHFLISFANGSNIKILMPHLIRSFFQDIDYPTINQLLTFLSIKCCQCTPEQLRILHTTKILSSDVNQCGLIDKVDAKRLCKFIHNTNLTSIRSTSSLF----------VIPIIHYCFGRQQAFLYPDLYVKSNSRCIKCASCSQIFTTCEFVKHTHLKINHINTVHWGFHSLNWRYFIYIYIFNADVEYHKNATLILDNIKSAF 683
            T LE   +  F  G   ++ +P ++ +  +D     IN +   L I C +CT +QL IL    IL      CGLI K DA+RLC  +         S   L+             I H CFG+ +  L P+LY   N+ CI+C  C  ++ T +FV H+H  + +  T HWGF S NWR ++ +       E       +LD+IK  F
Sbjct:   86 TVLEGETISCFVVGGEKRLCLPQILNTVLRDFSLQQINSVCDDLHIYCSRCTADQLEILKVMGILPFAAPSCGLITKTDAERLCNALIYGGTYPPHSKKELYGSIELELTEKSFKIYHECFGKCKGLLVPELYTSPNAPCIQCMDCRLMYPTHKFVVHSHKSLEN-RTCHWGFDSANWRAYVLLSPDYTGKEEKARLEQLLDDIKEKF 292

[Close]

BLAST of c-SKI_SMAD_bind domain-containing protein vs. Ensembl Zebrafish
Match: skib (v-ski avian sarcoma viral oncogene homolog b [Source:ZFIN;Acc:ZDB-GENE-990715-10])

HSP 1 Score: 117.087 bits (292), Expect = 1.162e-27
Identity = 69/211 (32.70%), Postives = 102/211 (48.34%), Query Frame = 3

Query:   90 TELENHFLISFANGSNIKILMPHLIRSFFQDIDYPTINQLLTFLSIKCCQCTPEQLRILHTTKILSSDVNQCGLIDKVDAKRLC-KFIHNTNLT---------SIRSTSSLFVIPIIHYCFGRQQAFLYPDLYVKSNSRCIKCASCSQIFTTCEFVKHTHLKINHINTVHWGFHSLNWRYFIYIYIFNAD-VEYHKNATL--ILDNIKSAF 683
            T LE   +  F  G   ++ +P ++ S  +D     IN +   L I C +CT +QL IL    IL      CGLI + DA+RLC   I+              SI    +     + H CFG+ +    P+LY   N+ CI+C  C  +F T +FV H+H ++ +  T HWGF S NWR +I   + + D  E  +N+TL  +L  +K  F
Sbjct:   82 TVLERETISCFVVGGEKRLCLPQILNSVLRDFSLQQINSVCDDLHIYCSRCTADQLEILKVMGILPFSAPSCGLITQTDAERLCNALIYGGTFPPHADKELSCSIELERTEKSFKVYHECFGKCKGLFVPELYTSPNAACIQCLDCRLMFPTHKFVVHSHKRLEN-RTCHWGFDSSNWRAYI---LLDQDYSEKEENSTLQQLLTELKGKF 288

[Close]

BLAST of c-SKI_SMAD_bind domain-containing protein vs. Ensembl Zebrafish
Match: skilb (SKI-like proto-oncogene b [Source:ZFIN;Acc:ZDB-GENE-080723-40])

HSP 1 Score: 105.916 bits (263), Expect = 4.130e-24
Identity = 58/216 (26.85%), Postives = 100/216 (46.30%), Query Frame = 3

Query:   72 SKIIQLTELENHFLISFANGSNIKILMPHLIRSFFQDIDYPTINQLLTFLSIKCCQCTPEQLRILHTTKILSSDVNQCGLIDKVDAKRLCKFIHNTNLTSI------RSTSSLFVIPIIHYCFGRQQAFLYPDLYVKSNSRCIKCASCSQIFTTCEFVKHTHLKINHINTVHWGFHSLNWRYFIYI---YIFNADVEYHKNATLILDNIKSAFLKE 692
            S  + +  LE   +  F+ G  +++ +P L+ +  +D     IN +   L + C +C   QL IL    IL      CGLI   DA+RLC  + +     +      +         + H C G+ Q    P LY   ++ C++C+ C  +F T  FV H+H + +   T HWGF S  W  ++ +   ++  AD E  + +   L+++K+ F +E
Sbjct:  120 STDLSMCSLEGESISCFSVGGELRLCLPQLLNTILRDFSLQQINSVCDQLYLYCSRCDATQLHILKVLGILPPGTPSCGLITLTDAQRLCNTLLHPGEEPLDREQEEKDGEESGGFWVEHQCLGKCQGLFVPQLYSSPDAPCVRCSQCRMLFCTERFVMHSHRQPDK-RTCHWGFDSAKWACYLQLAQRHLGTADEEKLQQS---LEDMKAKFQQE 331

[Close]

Query:   72 SKIIQLTELENHFLISFANGSNIKILMPHLIRSFFQDIDYPTINQLLTFLSIKCCQCTPEQLRILHTTKILSSDVNQCGLIDKVDAKRLCKFIHNTNLTSI------RSTSSLFVIPIIHYCFGRQQAFLYPDLYVKSNSRCIKCASCSQIFTTCEFVKHTHLKINHINTVHWGFHSLNWRYFIYI---YIFNADVEYHKNATLILDNIKSAFLKE 692
            S  + +  LE   +  F+ G  +++ +P L+ +  +D     IN +   L + C +C   QL IL    IL      CGLI   DA+RLC  + +     +      +         + H C G+ Q    P LY   ++ C++C+ C  +F T  FV H+H + +   T HWGF S  W  ++ +   ++  AD E  + +   L+++K+ F +E
Sbjct:  120 STDLSMCSLEGESISCFSVGGELRLCLPQLLNTILRDFSLQQINSVCDQLYLYCSRCDATQLHILKVLGILPPGTPSCGLITLTDAQRLCNTLLHPGEEPLDREQEEKDGEESGGFWVEHQCLGKCQGLFVPQLYSSPDAPCVRCSQCRMLFCTERFVMHSHRQPDK-RTCHWGFDSAKWACYLQLAQRHLGTADEEKLQQS---LEDMKAKFQQE 331

[Close]

BLAST of c-SKI_SMAD_bind domain-containing protein vs. Ensembl Zebrafish
Match: skila (SKI-like proto-oncogene a [Source:ZFIN;Acc:ZDB-GENE-070912-548])

HSP 1 Score: 103.219 bits (256), Expect = 1.281e-23
Identity = 58/209 (27.75%), Postives = 94/209 (44.98%), Query Frame = 3

Query:   96 LENHFLISFANGSNIKILMPHLIRSFFQDIDYPTINQLLTFLSIKCCQCTPEQLRILHTTKILSSDVNQCGLIDKVDAKRLCKFI--HNTNLTS-----------IRSTSSLFVIPIIHYCFGRQQAFLYPDLYVKSNSRCIKCASCSQIFTTCEFVKHTHLKINHINTVHWGFHSLNWRYFIYIYIFNADVEYHKNATLILDNIKSAF 683
            LE   +  F  G   ++ +P ++ S  +D     IN +   L + C +C  EQL IL    IL  +   CGLI   DA+RLC  +     N+++           ++ + + F   + H C G+ Q    P  YV+ ++ CI+C  C  +F+   FV H+H K     T HWGF S  W  ++ +   +   +       +LD +K  F
Sbjct:  159 LEGESISCFVVGGEKRLCLPQVLNSVLRDFSLQQINAVCDELYVYCSRCDAEQLHILKVLGILPFNAPSCGLITLTDAQRLCNALLRPGANISADPNSKLPGQGLLKESDASFQ--VEHQCLGKCQGLFVPHFYVQPDAPCIQCMECQLLFSPQNFVMHSH-KSPDKRTCHWGFDSAKWPCYLQLGRKHEGTQEEPQLKQLLDEMKEKF 364

[Close]

BLAST of c-SKI_SMAD_bind domain-containing protein vs. Ensembl Xenopus
Match: ENSXETT00000042147.1 (SKI-like proto-oncogene [Source:NCBI gene;Acc:100492636])

HSP 1 Score: 113.62 bits (283), Expect = 2.056e-26
Identity = 66/219 (30.14%), Postives = 101/219 (46.12%), Query Frame = 3

Query:   90 TELENHFLISFANGSNIKILMPHLIRSFFQDIDYPTINQLLTFLSIKCCQCTPEQLRILHTTKILSSDVNQCGLIDKVDAKRLC-------KFIHNT-------NLTSIRSTSSLFVIPIIHYCFGRQQAFLYPDLYVKSNSRCIKCASCSQIFTTCEFVKHTHLKINHINTVHWGFHSLNWRYFIYIYIFNADVEYHKNATLILDNIKSAFLKEDMKK 704
            TELE   +  F  G   ++ +P ++ S  +D     IN +   + I C +CT +QL IL    IL  +   CGLI   DA+RLC        F  N        +L  ++ T S F +   H C G+ Q    P L+ + ++ CI+C  C  +F+T  FV H+H   +   T HWGF S  W  ++++     D    K    +L  +K  F K++  K
Sbjct:  129 TELEGESISCFMVGGEKRLCLPQVLNSVLRDFSLQQINIVCDEMYIYCSRCTSDQLHILKVLGILPFNAPSCGLITLTDAQRLCNALLRPQTFPQNGSLLPAKNSLAQLKETGSAFEVE--HDCLGKCQGLFAPHLFSQPDAPCIQCLECYGMFSTQTFVMHSHRSPDK-RTCHWGFDSAKWHCYVHLSPKYLDTPEGKKMNALLKEMKEKFNKKNQPK 344

[Close]

BLAST of c-SKI_SMAD_bind domain-containing protein vs. Ensembl Xenopus
Match: SKI (SKI proto-oncogene [Source:NCBI gene;Acc:100486949])

HSP 1 Score: 110.153 bits (274), Expect = 3.132e-25
Identity = 61/212 (28.77%), Postives = 93/212 (43.87%), Query Frame = 3

Query:   96 LENHFLISFANGSNIKILMPHLIRSFFQDIDYPTINQLLTFLSIKCCQCTPEQLRILHTTKILSSDVNQCGLIDKVDAKRLCKFIHNTNLTSIRSTSSLFVIP-------------IIHYCFGRQQAFLYPDLYVKSNSRCIKCASCSQIFTTCEFVKHTHLKINHINTVHWGFHSLNWRYFIYIYIFNADV---EYHKNATLILDNIKSAF 683
            LE   +  F  G   ++ +P ++ S  +D     IN +   L + C +CT +QL IL    IL      CGLI K DA+RLC  +        R        P             + H CFG+ +    P+LY   ++ CI+C  C  ++   +FV H+H  + +  T HWGF S NWR +I +   N      E     + +L+ +K  F
Sbjct:   88 LEGETISCFVVGGEKRLCLPQILNSVLRDFSLQQINAVCDELHVYCSRCTADQLEILKVMGILPFSAPSCGLITKTDAERLCNALLYGGSYPPRCAKKSDFPPGPLELELTESSFRVYHECFGKCRGLFVPELYGHPSAPCIQCLDCRLMYPPHKFVVHSHKALEN-RTCHWGFDSANWRAYILLARDNPGAGGEEEQARLSRLLEEMKEKF 298

[Close]

BLAST of c-SKI_SMAD_bind domain-containing protein vs. Ensembl Xenopus
Match: arg1 (arginase 1 [Source:Xenbase;Acc:XB-GENE-966913])

HSP 1 Score: 69.3218 bits (168), Expect = 1.410e-12
Identity = 39/143 (27.27%), Postives = 63/143 (44.06%), Query Frame = 3

Query:  111 LISFANGSNIKILMPHLIRSFFQDIDYPTINQLLTFLSIKCCQCTPEQLRILHTTKILSSDVNQCGLIDKVDAKRLCKFIHNTNLTSIRSTSSLFVIPIIHYCFGRQQAFLYPDLYVKSNSRCIKCASCSQIFTTCEFVKHTH 539
            ++S       ++ +  +  +  ++  Y  I+     L I C QCTP QL IL     +     +CG+I K +A+RLCK     N          F   + H C    +    P  Y  S ++CIKC  C+  F+  +F+ H+H
Sbjct:   51 IVSLVIDGQERLCLAQISNTLLKNYSYNEIHNRRVALGITCVQCTPVQLEILRRAGAMPISSRRCGMITKREAERLCKSFLGENRPP--KLPDNFAFDVSHECAWGCRGSFIPARYNSSRAKCIKCTYCNMYFSPNKFIFHSH 191

[Close]

BLAST of c-SKI_SMAD_bind domain-containing protein vs. Ensembl Xenopus
Match: SKOR1 (SKI family transcriptional corepressor 1 [Source:NCBI gene;Acc:100491438])

HSP 1 Score: 70.4774 bits (171), Expect = 2.669e-12
Identity = 53/203 (26.11%), Postives = 90/203 (44.33%), Query Frame = 3

Query:  111 LISFANGSNIKILMPHLIRSFFQDIDYPTINQLLTFLSIKCCQCTPEQLRILHTTKILSSDVNQCGLIDKVDAKRLCK-FIHNTNLTSIRSTSSLFVIPIIHYC-FGRQQAFLYPDLYVKSNSRCIKCASCSQIFTTCEFVKHTHLKINHINTVHWGFHSLNWRYFIYIYIFNADVEYHKNATLILDNIKSAFLKEDMKKMKN 713
            ++S       ++ +  +  +  +   Y  I+     L I C QCTP QL IL     +     +CG+I K +A+RLCK F+       +      F   + H C +G + +F+ P  Y  S ++CIKCA C   F+  +F+ H+H   +   T     +  +WR  + +           N T   D++  ++  ED+K M N
Sbjct:   47 IVSLVIDGQERLCLAQISNTLLKSYSYNEIHNRRVALGITCVQCTPVQLEILRRAGAMPISSRRCGMITKREAERLCKSFLGEHRPPKLPEN---FAFDVAHECAWGCRGSFI-PARYNSSRAKCIKCAYCGLYFSPNKFIFHSHRTPDSKYTQPDAANFNSWRRHLRL-----------NDTTPSDDLSHSW--EDVKAMFN 232

[Close]

BLAST of c-SKI_SMAD_bind domain-containing protein vs. Ensembl Xenopus
Match: SKOR1 (SKI family transcriptional corepressor 1 [Source:NCBI gene;Acc:100491438])

HSP 1 Score: 70.0922 bits (170), Expect = 2.840e-12
Identity = 53/203 (26.11%), Postives = 90/203 (44.33%), Query Frame = 3

Query:  111 LISFANGSNIKILMPHLIRSFFQDIDYPTINQLLTFLSIKCCQCTPEQLRILHTTKILSSDVNQCGLIDKVDAKRLCK-FIHNTNLTSIRSTSSLFVIPIIHYC-FGRQQAFLYPDLYVKSNSRCIKCASCSQIFTTCEFVKHTHLKINHINTVHWGFHSLNWRYFIYIYIFNADVEYHKNATLILDNIKSAFLKEDMKKMKN 713
            ++S       ++ +  +  +  +   Y  I+     L I C QCTP QL IL     +     +CG+I K +A+RLCK F+       +      F   + H C +G + +F+ P  Y  S ++CIKCA C   F+  +F+ H+H   +   T     +  +WR  + +           N T   D++  ++  ED+K M N
Sbjct:   47 IVSLVIDGQERLCLAQISNTLLKSYSYNEIHNRRVALGITCVQCTPVQLEILRRAGAMPISSRRCGMITKREAERLCKSFLGEHRPPKLPEN---FAFDVAHECAWGCRGSFI-PARYNSSRAKCIKCAYCGLYFSPNKFIFHSHRTPDSKYTQPDAANFNSWRRHLRL-----------NDTTPSDDLSHSW--EDVKAMFN 232

[Close]

BLAST of c-SKI_SMAD_bind domain-containing protein vs. Ensembl Mouse
Match: Ski (ski sarcoma viral oncogene homolog (avian) [Source:MGI Symbol;Acc:MGI:98310])

HSP 1 Score: 119.013 bits (297), Expect = 2.595e-28
Identity = 73/256 (28.52%), Postives = 113/256 (44.14%), Query Frame = 3

Query:   90 TELENHFLISFANGSNIKILMPHLIRSFFQDIDYPTINQLLTFLSIKCCQCTPEQLRILHTTKILSSDVNQCGLIDKVDAKRLCKFIHNTNL------TSIRSTSSLFV------IPIIHYCFGRQQAFLYPDLYVKSNSRCIKCASCSQIFTTCEFVKHTHLKINHINTVHWGFHSLNWRYFIYIYIFNADVEYHKNATLILDNIKSAFLKEDMKKMKNKLPWRPKNLRINIPPISTNKVNSIFQEMKPIFKRKD 821
            T LE   +  F  G   ++ +P ++ S  +D     IN +   L I C +CT +QL IL    IL      CGLI K DA+RLC  +             + ++ +L +      + + H CFG+ +  L P+LY   ++ CI+C  C  ++   +FV H+H  + +  T HWGF S NWR +I +       E        LD++K  F  +   K K ++P      R++ PP S            P    KD
Sbjct:  103 TVLEGETISCFVVGGEKRLCLPQILNSVLRDFSLQQINSVCDELHIYCSRCTADQLEILKVMGILPFSAPSCGLITKTDAERLCNALLYGGAYPPPCKKELAASLALGLELSERSVRVYHECFGKCKGLLVPELYSSPSAACIQCLDCRLMYPPHKFVVHSHKALEN-RTCHWGFDSANWRAYILLSQDYTGKEEQARLGRCLDDVKEKF--DYANKYKRRVP------RVSEPPASIRPKTDDTSSQSPASSEKD 349

[Close]

BLAST of c-SKI_SMAD_bind domain-containing protein vs. Ensembl Mouse
Match: Ski (ski sarcoma viral oncogene homolog (avian) [Source:MGI Symbol;Acc:MGI:98310])

HSP 1 Score: 117.472 bits (293), Expect = 8.323e-28
Identity = 71/253 (28.06%), Postives = 111/253 (43.87%), Query Frame = 3

Query:   99 ENHFLISFANGSNIKILMPHLIRSFFQDIDYPTINQLLTFLSIKCCQCTPEQLRILHTTKILSSDVNQCGLIDKVDAKRLCKFIHNTNL------TSIRSTSSLFV------IPIIHYCFGRQQAFLYPDLYVKSNSRCIKCASCSQIFTTCEFVKHTHLKINHINTVHWGFHSLNWRYFIYIYIFNADVEYHKNATLILDNIKSAFLKEDMKKMKNKLPWRPKNLRINIPPISTNKVNSIFQEMKPIFKRKD 821
            E   +  F  G   ++ +P ++ S  +D     IN +   L I C +CT +QL IL    IL      CGLI K DA+RLC  +             + ++ +L +      + + H CFG+ +  L P+LY   ++ CI+C  C  ++   +FV H+H  + +  T HWGF S NWR +I +       E        LD++K  F  +   K K ++P      R++ PP S            P    KD
Sbjct:   54 EGETISCFVVGGEKRLCLPQILNSVLRDFSLQQINSVCDELHIYCSRCTADQLEILKVMGILPFSAPSCGLITKTDAERLCNALLYGGAYPPPCKKELAASLALGLELSERSVRVYHECFGKCKGLLVPELYSSPSAACIQCLDCRLMYPPHKFVVHSHKALEN-RTCHWGFDSANWRAYILLSQDYTGKEEQARLGRCLDDVKEKF--DYANKYKRRVP------RVSEPPASIRPKTDDTSSQSPASSEKD 297

[Close]

BLAST of c-SKI_SMAD_bind domain-containing protein vs. Ensembl Mouse
Match: Skil (SKI-like [Source:MGI Symbol;Acc:MGI:106203])

HSP 1 Score: 112.849 bits (281), Expect = 1.949e-26
Identity = 65/223 (29.15%), Postives = 103/223 (46.19%), Query Frame = 3

Query:   90 TELENHFLISFANGSNIKILMPHLIRSFFQDIDYPTINQLLTFLSIKCCQCTPEQLRILHTTKILSSDVNQCGLIDKVDAKRLC-------KFIHN-------TNLTSIRSTSSLFVIPIIHYCFGRQQAFLYPDLYVKSNSRCIKCASCSQIFTTCEFVKHTHLKINHINTVHWGFHSLNWRYFIYIYIFNADVEYHKNATLILDNIKSAFLKEDMKKMKNK 716
            T LE   +  F  G   ++ +P ++ S  ++     IN +   L I C +CT +QL IL    IL  +   CGLI   DA+RLC        F  N       ++L  ++ T S F +   H C G+ Q    P  YV+ ++ CI+C  C  +F    FV H+H   +   T HWGF S  W  ++++          K   +IL+ +K  F   + K++++K
Sbjct:   64 TLLEGESISCFQVGGEKRLCLPQVLNSVLREFSLQQINTVCDELYIYCSRCTSDQLHILKVLGILPFNAPSCGLITLTDAQRLCNALLRPRTFPQNGSILPAKSSLAQLKETGSAFEVE--HECLGKCQGLFAPQFYVQPDAPCIQCLECCGMFAPQTFVMHSHRSPDK-RTCHWGFESAKWHCYLHVNQKYLGTPEEKKLKIILEEMKEKFSMRNGKRIQSK 283

[Close]

BLAST of c-SKI_SMAD_bind domain-containing protein vs. Ensembl Mouse
Match: Skil (SKI-like [Source:MGI Symbol;Acc:MGI:106203])

HSP 1 Score: 112.464 bits (280), Expect = 3.523e-26
Identity = 65/223 (29.15%), Postives = 103/223 (46.19%), Query Frame = 3

Query:   90 TELENHFLISFANGSNIKILMPHLIRSFFQDIDYPTINQLLTFLSIKCCQCTPEQLRILHTTKILSSDVNQCGLIDKVDAKRLC-------KFIHN-------TNLTSIRSTSSLFVIPIIHYCFGRQQAFLYPDLYVKSNSRCIKCASCSQIFTTCEFVKHTHLKINHINTVHWGFHSLNWRYFIYIYIFNADVEYHKNATLILDNIKSAFLKEDMKKMKNK 716
            T LE   +  F  G   ++ +P ++ S  ++     IN +   L I C +CT +QL IL    IL  +   CGLI   DA+RLC        F  N       ++L  ++ T S F +   H C G+ Q    P  YV+ ++ CI+C  C  +F    FV H+H   +   T HWGF S  W  ++++          K   +IL+ +K  F   + K++++K
Sbjct:  144 TLLEGESISCFQVGGEKRLCLPQVLNSVLREFSLQQINTVCDELYIYCSRCTSDQLHILKVLGILPFNAPSCGLITLTDAQRLCNALLRPRTFPQNGSILPAKSSLAQLKETGSAFEVE--HECLGKCQGLFAPQFYVQPDAPCIQCLECCGMFAPQTFVMHSHRSPDK-RTCHWGFESAKWHCYLHVNQKYLGTPEEKKLKIILEEMKEKFSMRNGKRIQSK 363

[Close]

BLAST of c-SKI_SMAD_bind domain-containing protein vs. Ensembl Mouse
Match: Skil (SKI-like [Source:MGI Symbol;Acc:MGI:106203])

HSP 1 Score: 112.079 bits (279), Expect = 4.690e-26
Identity = 65/223 (29.15%), Postives = 103/223 (46.19%), Query Frame = 3

Query:   90 TELENHFLISFANGSNIKILMPHLIRSFFQDIDYPTINQLLTFLSIKCCQCTPEQLRILHTTKILSSDVNQCGLIDKVDAKRLC-------KFIHN-------TNLTSIRSTSSLFVIPIIHYCFGRQQAFLYPDLYVKSNSRCIKCASCSQIFTTCEFVKHTHLKINHINTVHWGFHSLNWRYFIYIYIFNADVEYHKNATLILDNIKSAFLKEDMKKMKNK 716
            T LE   +  F  G   ++ +P ++ S  ++     IN +   L I C +CT +QL IL    IL  +   CGLI   DA+RLC        F  N       ++L  ++ T S F +   H C G+ Q    P  YV+ ++ CI+C  C  +F    FV H+H   +   T HWGF S  W  ++++          K   +IL+ +K  F   + K++++K
Sbjct:  144 TLLEGESISCFQVGGEKRLCLPQVLNSVLREFSLQQINTVCDELYIYCSRCTSDQLHILKVLGILPFNAPSCGLITLTDAQRLCNALLRPRTFPQNGSILPAKSSLAQLKETGSAFEVE--HECLGKCQGLFAPQFYVQPDAPCIQCLECCGMFAPQTFVMHSHRSPDK-RTCHWGFESAKWHCYLHVNQKYLGTPEEKKLKIILEEMKEKFSMRNGKRIQSK 363

[Close]

BLAST of c-SKI_SMAD_bind domain-containing protein vs. UniProt/SwissProt
Match: sp|Q60698|SKI_MOUSE (Ski oncogene OS=Mus musculus OX=10090 GN=Ski PE=1 SV=2)

HSP 1 Score: 119.013 bits (297), Expect = 1.696e-27
Identity = 73/256 (28.52%), Postives = 113/256 (44.14%), Query Frame = 3

Query:   90 TELENHFLISFANGSNIKILMPHLIRSFFQDIDYPTINQLLTFLSIKCCQCTPEQLRILHTTKILSSDVNQCGLIDKVDAKRLCKFIHNTNL------TSIRSTSSLFV------IPIIHYCFGRQQAFLYPDLYVKSNSRCIKCASCSQIFTTCEFVKHTHLKINHINTVHWGFHSLNWRYFIYIYIFNADVEYHKNATLILDNIKSAFLKEDMKKMKNKLPWRPKNLRINIPPISTNKVNSIFQEMKPIFKRKD 821
            T LE   +  F  G   ++ +P ++ S  +D     IN +   L I C +CT +QL IL    IL      CGLI K DA+RLC  +             + ++ +L +      + + H CFG+ +  L P+LY   ++ CI+C  C  ++   +FV H+H  + +  T HWGF S NWR +I +       E        LD++K  F  +   K K ++P      R++ PP S            P    KD
Sbjct:  101 TVLEGETISCFVVGGEKRLCLPQILNSVLRDFSLQQINSVCDELHIYCSRCTADQLEILKVMGILPFSAPSCGLITKTDAERLCNALLYGGAYPPPCKKELAASLALGLELSERSVRVYHECFGKCKGLLVPELYSSPSAACIQCLDCRLMYPPHKFVVHSHKALEN-RTCHWGFDSANWRAYILLSQDYTGKEEQARLGRCLDDVKEKF--DYANKYKRRVP------RVSEPPASIRPKTDDTSSQSPASSEKD 347

[Close]

BLAST of c-SKI_SMAD_bind domain-containing protein vs. UniProt/SwissProt
Match: sp|P12755|SKI_HUMAN (Ski oncogene OS=Homo sapiens OX=9606 GN=SKI PE=1 SV=1)

HSP 1 Score: 114.775 bits (286), Expect = 4.564e-26
Identity = 63/210 (30.00%), Postives = 98/210 (46.67%), Query Frame = 3

Query:   90 TELENHFLISFANGSNIKILMPHLIRSFFQDIDYPTINQLLTFLSIKCCQCTPEQLRILHTTKILSSDVNQCGLIDKVDAKRLCKFIHNTNL------TSIRSTSSLFV------IPIIHYCFGRQQAFLYPDLYVKSNSRCIKCASCSQIFTTCEFVKHTHLKINHINTVHWGFHSLNWRYFIYIYIFNADVEYHKNATLILDNIKSAF 683
            T LE   +  F  G   ++ +P ++ S  +D     IN +   L I C +CT +QL IL    IL      CGLI K DA+RLC  +             + ++ +L +      + + H CFG+ +  L P+LY   ++ CI+C  C  ++   +FV H+H  + +  T HWGF S NWR +I +       E        LD++K  F
Sbjct:  103 TVLEGETISCFVVGGEKRLCLPQILNSVLRDFSLQQINAVCDELHIYCSRCTADQLEILKVMGILPFSAPSCGLITKTDAERLCNALLYGGAYPPPCKKELAASLALGLELSERSVRVYHECFGKCKGLLVPELYSSPSAACIQCLDCRLMYPPHKFVVHSHKALEN-RTCHWGFDSANWRAYILLSQDYTGKEEQARLGRCLDDVKEKF 311

[Close]

BLAST of c-SKI_SMAD_bind domain-containing protein vs. UniProt/SwissProt
Match: sp|P17863|SKI_AVIES (Transforming protein Ski OS=Avian erythroblastosis virus (strain Sloan-Kettering) OX=11862 GN=V-SKI PE=1 SV=1)

HSP 1 Score: 112.079 bits (279), Expect = 9.351e-26
Identity = 73/246 (29.67%), Postives = 111/246 (45.12%), Query Frame = 3

Query:   90 TELENHFLISFANGSNIKILMPHLIRSFFQDIDYPTINQLLTFLSIKCCQCTPEQLRILHTTKILSSDVNQCGLIDKVDAKRLCKFIHNTNL------TSIRSTSSLFVIP----IIHYCFGRQQAFLYPDLYVKSNSRCIKCASCSQIFTTCEFVKHTHLKINHINTVHWGFHSLNWRYFIYIYIFNADVEYHKNATLILDNIKSAFLKEDMKKMKNKLPWRPKNLRINIPPISTNKVNSIFQEM 797
            T LE   +  F  G   ++ +P ++ S  +D     IN +   L I C +CT +QL IL    IL      CGLI K DA+RLC  +               ST  L +      + H CFG+ +  L P+LY   ++ CI+C  C  ++   +FV H+H  + +  T HWGF S NWR +I +       E       +LD +K  F  +   K K K P   ++ R+ +      + N +F+ M
Sbjct:   65 TILEGETISCFVVGGEKRLCLPQILNSVLRDFSLQQINSVCDELHIYCSRCTADQLEILKVMGILPFSAPSCGLITKTDAERLCNALLYGGTYPPHCKKEFSSTIELELTEKSFKVYHECFGKCKGLLVPELYSNPSAACIQCLDCRLMYPPHKFVVHSHKSLEN-RTCHWGFDSANWRSYILLSQDYTGKEEKARLGQLLDEMKEKF--DYNNKYKRKAPRNRESPRVQL------RRNKMFKTM 301

[Close]

BLAST of c-SKI_SMAD_bind domain-containing protein vs. UniProt/SwissProt
Match: sp|Q9TUG2|SKI_HORSE (Ski oncogene OS=Equus caballus OX=9796 GN=SKI PE=2 SV=1)

HSP 1 Score: 112.849 bits (281), Expect = 1.907e-25
Identity = 70/243 (28.81%), Postives = 111/243 (45.68%), Query Frame = 3

Query:   90 TELENHFLISFANGSNIKILMPHLIRSFFQDIDYPTINQLLTFLSIKCCQCTPEQLRILHTTKILSSDVNQCGLIDKVDAKRLCKFIHNTNL------TSIRSTSSLFV------IPIIHYCFGRQQAFLYPDLYVKSNSRCIKCASCSQIFTTCEFVKHTHLKINHINTVHWGFHSLNWRYFIYIYIFNADVEYHKNATLILDNIKSAFLKEDMKKMKNKLPWRPKNLRINI-PPISTNKVN 779
            T LE   +  F  G   ++ +P ++ S  +D     IN +   L   C +CT +QL IL    IL      CGLI K DA+RLC  +             + ++ +L +      + + H CFG+ +  L P+LY   ++ CI+C  C  ++   +FV H+H  + +  T HWGF S NWR +I +       E        LD++K  F  +   K K ++P      R++  PP S  K +
Sbjct:  103 TVLEGETISCFVVGGEKRLCLPQILNSVLRDFSLQQINSVCDELHTYCSRCTADQLEILKVMGILPFSAPSCGLITKTDAERLCNALLYGGAYPPPCKKELAASLALGLELSERSVRVYHECFGKCKGLLVPELYSSPSAACIQCLDCRLMYPPHKFVVHSHKALEN-RTCHWGFDSANWRAYILLSQDYTGKEEQTRLGRCLDDVKEKF--DYGNKYKRRVP------RVSSEPPASIRKTD 336

[Close]

BLAST of c-SKI_SMAD_bind domain-containing protein vs. UniProt/SwissProt
Match: sp|P49140|SKI_CHICK (Ski oncogene OS=Gallus gallus OX=9031 GN=SKI PE=1 SV=1)

HSP 1 Score: 112.849 bits (281), Expect = 1.917e-25
Identity = 63/208 (30.29%), Postives = 95/208 (45.67%), Query Frame = 3

Query:   96 LENHFLISFANGSNIKILMPHLIRSFFQDIDYPTINQLLTFLSIKCCQCTPEQLRILHTTKILSSDVNQCGLIDKVDAKRLCKFI------------HNTNLTSIRSTSSLFVIPIIHYCFGRQQAFLYPDLYVKSNSRCIKCASCSQIFTTCEFVKHTHLKINHINTVHWGFHSLNWRYFIYIYIFNADVEYHKNATLILDNIKSAF 683
            LE   +  F  G   ++ +P ++ S  +D     IN +   L I C +CT +QL IL    IL      CGLI K DA+RLC  +              ++   +  T   F   + H CFG+ +  L P+LY   ++ CI+C  C  ++   +FV H+H  + +  T HWGF S NWR +I +       E       +LD +K  F
Sbjct:   88 LEGETISCFVVGGEKRLCLPQILNSVLRDFSLQQINSVCDELHIYCSRCTADQLEILKVMGILPFSAPSCGLITKTDAERLCNALLYGGTYPPHCKKEFSSTIELELTEKSFK--VYHECFGKCKGLLVPELYSNPSAACIQCLDCRLMYPPHKFVVHSHKSLEN-RTCHWGFDSANWRSYILLSQDYTGKEEKARLGQLLDEMKEKF 292

[Close]

BLAST of c-SKI_SMAD_bind domain-containing protein vs. TrEMBL
Match: A0A1Y1MFT2 (c-SKI_SMAD_bind domain-containing protein OS=Photinus pyralis OX=7054 GN=PPYR_13790 PE=4 SV=1)

HSP 1 Score: 142.895 bits (359), Expect = 2.527e-33
Identity = 75/199 (37.69%), Postives = 101/199 (50.75%), Query Frame = 3

Query:   90 TELENHFLISFANGSNIKILMPHLIRSFFQDIDYPTINQLLTFLSIKCCQCTPEQLRILHTTKILSSDVNQCGLIDKVDAKRLC-KFIHNTNLTSIRSTSSLFVIPIIHYCFGRQQAFLYPDLYVKSNSRCIKCASCSQIFTTCEFVKHTHLKINHINTVHWGFHSLNWRYFIYIYIFNADVEYHKNATLILDNIKSAF 683
            T LE   +  F  G   ++ +P ++ S  +D     INQ    L I C +CTPEQL +L    IL S    CGLI K DA+RLC   +H     S+R         + H CFG+ +    PDLY   ++RCI+C  CS  FT  +FV H H  + +  TVHWGF S NWR +++I     D   H+  T  LD IK  +
Sbjct:   72 TTLEGETISCFVVGGEKRLCLPQVLNSVLRDFSLMQINQECDQLQIYCSRCTPEQLNVLKNQGILPSSAPSCGLITKTDAERLCSALLHCQVYPSLRPPKGTLSFTVYHECFGKCRGICVPDLYTGKDARCIECMDCSGAFTPQQFVCHVHRDLEN-RTVHWGFDSSNWRSYLHICKDQID---HERLTKYLDVIKDQY 266

[Close]

BLAST of c-SKI_SMAD_bind domain-containing protein vs. TrEMBL
Match: A0A482VDX3 (Ski Sno and/or c-SKI SMAD bind domain containing protein OS=Asbolus verrucosus OX=1661398 GN=BDFB_011750 PE=4 SV=1)

HSP 1 Score: 138.658 bits (348), Expect = 3.225e-33
Identity = 76/234 (32.48%), Postives = 112/234 (47.86%), Query Frame = 3

Query:   90 TELENHFLISFANGSNIKILMPHLIRSFFQDIDYPTINQLLTFLSIKCCQCTPEQLRILHTTKILSSDVNQCGLIDKVDAKRLC-KFIHNTNLTSIRSTSSLFVIPIIHYCFGRQQAFLYPDLYVKSNSRCIKCASCSQIFTTCEFVKHTHLKINHINTVHWGFHSLNWRYFIYIYIFNADVEYHKNATLILDNIKSAFLKEDMKKMKNKLPWR-PKNL--------RINIPPI 761
            T LE   +  F  G   ++ +P ++ S  +D   P IN     L I C +CTPEQL +L    IL S     GLI K DA+RLC   +H  ++  IR         + H CFG+ +   +P+L+   N++CI+C  C   F+  +FV H H   +   TVHWGF S NWR ++ +     D + H+     +D +K  F          K+P+  P+N+          NIPPI
Sbjct:   73 TILEGETISCFVVGGEKRLCLPQVLNSVLRDFSLPQINHECDQLQIYCSRCTPEQLNVLKNGGILPSGAASSGLITKTDAERLCSALLHGQDIPQIRPRKGSVSFTVYHKCFGKCRGVCFPELFTSKNAKCIECTECRGGFSPQQFVCHVHKHFSENRTVHWGFDSANWRVYLRVA---KDQQDHEQCVKYIDELKEQF--------DGKMPFPLPQNIYAGIKRKQHPNIPPI 295

[Close]

BLAST of c-SKI_SMAD_bind domain-containing protein vs. TrEMBL
Match: A0A1Z5LAJ0 (Transforming protein Ski (Fragment) OS=Ornithodoros moubata OX=6938 PE=4 SV=1)

HSP 1 Score: 140.584 bits (353), Expect = 1.433e-32
Identity = 70/240 (29.17%), Postives = 119/240 (49.58%), Query Frame = 3

Query:   90 TELENHFLISFANGSNIKILMPHLIRSFFQDIDYPTINQLLTFLSIKCCQCTPEQLRILHTTKILSSDVNQCGLIDKVDAKRLC-KFIHNTNLTSIRSTSSLFVIPIIHYCFGRQQAFLYPDLYVKSNSRCIKCASCSQIFTTCEFVKHTHLKINHINTVHWGFHSLNWRYFIYIYIFNADVEYHKNATLILDNIKSAFLKEDMKKMKNKLPWRPKNLRINIPPISTNKVNSIFQEMKPI 806
            T LENH +  F  G   ++ +P ++ +  +D     IN +   L I C +C  EQL +L  +++L S    CGLI K DA+RLC + +H++      +    F +P+ H CFG     L+PD Y + ++ C++C+ CS +F+   FV H H +     T HWGF S NWR ++ +       +     T ++D++K+ F+ +  +K              N PP+  +K     ++  P+
Sbjct:   94 TILENHTISCFCVGGERRLCLPQILTTVLRDFTLQQINGVCDDLQIFCSRCNAEQLEVLKVSRVLPSCAPSCGLITKTDAERLCAELLHSSGDPVDETVLGTFQVPVYHECFGGTHGDLFPDAYTEYDAACVRCSECSAMFSPRRFVCHAH-RGRENRTCHWGFDSANWRAYVLLDEEQVGGQDVVRLTRVMDDVKAKFVTDGKRKQ-------------NPPPVEASKKKMRAEDEAPL 319

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BLAST of c-SKI_SMAD_bind domain-containing protein vs. TrEMBL
Match: A0A1B6GH89 (c-SKI_SMAD_bind domain-containing protein (Fragment) OS=Cuerna arida OX=1464854 GN=g.22114 PE=4 SV=1)

HSP 1 Score: 135.961 bits (341), Expect = 3.102e-32
Identity = 72/212 (33.96%), Postives = 107/212 (50.47%), Query Frame = 3

Query:   90 TELENHFLISFANGSNIKILMPHLIRSFFQDIDYPTINQLLTFLSIKCCQCTPEQLRILHTTKILSSDVNQCGLIDKVDAKRLCKFIHNTNLTSIR--STSSLFVIPIIHYCFGRQQAFLYPDLYVKSNSRCIKCASCSQIFTTCEFVKHTHLKINHINTVHWGFHSLNWRYFIYIYIFNADVEYHKNATLILDNIKSAFLKEDMKKMKNKL 719
            T LE   +  F  G   ++ +PH++ S  +D   P INQ+   L I C +C PEQL  L  + IL S    CGLI K DA+RLC  + + N  S R    +    I + H CFG+ +    P+LY  ++++CI+C  C  +FT   FV H H  + +  T HWGF S NWR ++ +     D   H+    +LD  K  F   +  K + ++
Sbjct:   87 TVLEGESISCFVVGGEKRLCLPHILNSVLRDFSLPQINQVCDELQIFCSRCNPEQLEELKVSGILPSTAPSCGLITKTDAERLCSALLHRNAPSARLLDKAVTIQIKVYHECFGKCRGVCMPELYTDTSAQCIECTECHGLFTPQTFVCHAHRYLEN-RTCHWGFDSSNWRAYLLLVEDQPD---HERRAKLLDFFKEQFTDPEHNKKRKEM 294

[Close]

BLAST of c-SKI_SMAD_bind domain-containing protein vs. TrEMBL
Match: A0A484B881 (c-SKI_SMAD_bind domain-containing protein OS=Drosophila navojoa OX=7232 GN=AWZ03_009060 PE=4 SV=1)

HSP 1 Score: 134.035 bits (336), Expect = 4.583e-32
Identity = 76/224 (33.93%), Postives = 113/224 (50.45%), Query Frame = 3

Query:   87 LTELENHFLISFANGSNIKILMPHLIRSFFQDIDYPTINQLLTFLSIKCCQCTPEQLRILHTTKILSSDVNQCGLIDKVDAKRLC-KFIHNTNLTSIRSTSSL----FVIPIIHYCFGRQQAFLYPDLYVKSNSRCIKCASCSQIFTTCEFVKHTHLKINHINTVHWGFHSLNWRYFIYIYIFNADVEYHKNATLILDNIKSAFLKEDMKKMKNKLPWRPKNLR 743
            +T LE   +  F+ G  +++ +P  + +   D     IN +   L I C QCTPEQL      KIL SDV   GLI + DA+RLC   +H ++  S     SL        + H CFG+ +    PD+Y      CI+C  C+  F+  +FV H H K+ +  T HWGF S NW  ++++ +   DVE  +    ILD +K   LKE M K + +L  + + +R
Sbjct:   95 VTRLEGKAIGCFSMGGEMRLCLPQFLNNVLSDFTLDQINGIFEDLGISCSQCTPEQLVEFKAAKILPSDVKGSGLITRTDAERLCAALLHRSDRNSYVPVESLGKGALSFQVYHKCFGKCEGICTPDMYSYQKPTCIQCLECNCWFSPQKFVGHVHRKVEN-RTCHWGFDSRNWHDYLHVAL---DVENREKYQRILDQLKEVELKE-MHKAQCELDHKKRKVR 313

[Close]

BLAST of c-SKI_SMAD_bind domain-containing protein vs. Ensembl Cavefish
Match: skib (ski oncogene-like [Source:NCBI gene;Acc:103031474])

HSP 1 Score: 125.561 bits (314), Expect = 1.704e-30
Identity = 65/205 (31.71%), Postives = 97/205 (47.32%), Query Frame = 3

Query:   90 TELENHFLISFANGSNIKILMPHLIRSFFQDIDYPTINQLLTFLSIKCCQCTPEQLRILHTTKILSSDVNQCGLIDKVDAKRLC-KFIHNTNLTSIRSTSSLFV------IPIIHYCFGRQQAFLYPDLYVKSNSRCIKCASCSQIFTTCEFVKHTHLKINHINTVHWGFHSLNWRYFIYIYIFNADVEYHKNATLILDNIKSAF 683
            T LE   +  F  G   ++ +P ++ +  +D     IN +   L + C +CT EQL +L    +L      CGLI + DA+RLC   +H   L S    ++L +      +P+ H CFGR      P+LY    + C++CA C  +F    FV H+H +  +  T HWGF S NWR +I +    A    H      LD +K  F
Sbjct:   83 TVLERETISCFVVGGEKRLCLPQILNTVLRDFSLQQINAVCDELHVYCSRCTAEQLEVLKVVGVLPFSAPSCGLITQTDAERLCNALVHGGALPSRGGPAALELATTDKSVPVYHECFGRCDGVFVPELYSGPGAACVQCADCGLMFPARRFVVHSHRRREN-RTCHWGFDSANWRAYILLDRDRAPPTEHTELQRRLDRLKEKF 286

[Close]

BLAST of c-SKI_SMAD_bind domain-containing protein vs. Ensembl Cavefish
Match: skib (ski oncogene-like [Source:NCBI gene;Acc:103031474])

HSP 1 Score: 124.79 bits (312), Expect = 2.629e-30
Identity = 65/205 (31.71%), Postives = 97/205 (47.32%), Query Frame = 3

Query:   90 TELENHFLISFANGSNIKILMPHLIRSFFQDIDYPTINQLLTFLSIKCCQCTPEQLRILHTTKILSSDVNQCGLIDKVDAKRLC-KFIHNTNLTSIRSTSSLFV------IPIIHYCFGRQQAFLYPDLYVKSNSRCIKCASCSQIFTTCEFVKHTHLKINHINTVHWGFHSLNWRYFIYIYIFNADVEYHKNATLILDNIKSAF 683
            T LE   +  F  G   ++ +P ++ +  +D     IN +   L + C +CT EQL +L    +L      CGLI + DA+RLC   +H   L S    ++L +      +P+ H CFGR      P+LY    + C++CA C  +F    FV H+H +  +  T HWGF S NWR +I +    A    H      LD +K  F
Sbjct:   83 TVLERETISCFVVGGEKRLCLPQILNTVLRDFSLQQINAVCDELHVYCSRCTAEQLEVLKVVGVLPFSAPSCGLITQTDAERLCNALVHGGALPSRGGPAALELATTDKSVPVYHECFGRCDGVFVPELYSGPGAACVQCADCGLMFPARRFVVHSHRRREN-RTCHWGFDSANWRAYILLDRDRAPPTEHTELQRRLDRLKEKF 286

[Close]

BLAST of c-SKI_SMAD_bind domain-containing protein vs. Ensembl Cavefish
Match: skia (ski oncogene [Source:NCBI gene;Acc:103046211])

HSP 1 Score: 116.701 bits (291), Expect = 1.331e-27
Identity = 58/186 (31.18%), Postives = 85/186 (45.70%), Query Frame = 3

Query:   90 TELENHFLISFANGSNIKILMPHLIRSFFQDIDYPTINQLLTFLSIKCCQCTPEQLRILHTTKILSSDVNQCGLIDKVDAKRLC-KFIHNTNL-----------TSIRSTSSLFVIPIIHYCFGRQQAFLYPDLYVKSNSRCIKCASCSQIFTTCEFVKHTHLKINHINTVHWGFHSLNWRYFIYI 611
            T LE   +  F  G   ++ +P ++ +  +++    IN +   L I C +CT EQL IL    +L      CGLI K DA+RLC   +H                 +    +   I + H CFGR    L P+LY   ++ CI+CA C  +     FV H H    +  T HWGF S NWR ++ +
Sbjct:  108 TVLEGETISCFVVGGEKRLCLPQILNTVLRELSLQQINSVCDQLHIYCSRCTAEQLEILKVVGVLPFSAPSCGLITKTDAERLCNALVHGAGYPGKLAQEQEVEAEVHEGKAEAGIKVYHECFGRCAGVLLPELYTSPSAPCIRCAHCGLLLAPRRFVAHAHGTPEN-RTCHWGFDSDNWRAYVLL 292

[Close]

BLAST of c-SKI_SMAD_bind domain-containing protein vs. Ensembl Cavefish
Match: skila (SKI like proto-oncogene [Source:NCBI gene;Acc:103032490])

HSP 1 Score: 106.301 bits (264), Expect = 3.477e-24
Identity = 58/213 (27.23%), Postives = 94/213 (44.13%), Query Frame = 3

Query:   96 LENHFLISFANGSNIKILMPHLIRSFFQDIDYPTINQLLTFLSIKCCQCTPEQLRILHTTKILSSDVNQCGLIDKVDAKRLCKFIHNTNL------TSIRSTSSLFVIPIIHYCFGRQQAFLYPDLYVKSNSRCIKCASCSQIFTTCEFVKHTHLKINHINTVHWGFHSLNWRYFIYIYIFNADVEYHKNATLILDNIKSAFLKEDMKKMKNK 716
            LE   +  F  G   ++ +P ++ S  +D     IN +   L + C +C  EQL IL    IL  +   CGLI   DA+RLC  +           + +++  S     + H C G+ Q    P  YV+ ++ CI+C  C  +F+   FV H+H   +   T HWGF S  W  ++ +               +LD +K+ F    +K+  +K
Sbjct:  154 LEGESISCFVVGGEKRLCLPQVLNSVLRDFSLQQINAVCDELYVYCSRCDAEQLHILKVLGILPFNAPSCGLITLTDAQRLCNALLRPGTAIHVEQSMLKAKDSEAGFQVEHQCLGKCQGLFVPQFYVQPDAPCIRCMECQLLFSPQNFVMHSHCSPDK-RTCHWGFDSAKWACYLQLSRRYQGAAEEPKLRQLLDEMKNKFHSPTLKRTLDK 365

[Close]

BLAST of c-SKI_SMAD_bind domain-containing protein vs. Ensembl Cavefish
Match: skilb (ski-like protein [Source:NCBI gene;Acc:103027845])

HSP 1 Score: 99.3673 bits (246), Expect = 6.275e-22
Identity = 65/247 (26.32%), Postives = 106/247 (42.91%), Query Frame = 3

Query:   96 LENHFLISFANGSNIKILMPHLIRSFFQDIDYPTINQLLTFLSIKCCQCTPEQLRILHTTKILSSDVNQCGLIDKVDAKRLCKFIHNTNLTSIRSTSSLFVIP-------------------IIHYCFGRQQAFLYPDLYVKSNSRCIKCASCSQIFTTCEFVKHTHLKINHINTVHWGFHSLNWRYFIYIYIFNADVEYHKNATLILDNIKSAFLKEDMKKMKNKLPWRPKNLRINIPPISTNKVN 779
            LE   +  F+ G  +++ +P ++ +  +D     IN +   L + C +C   QL++L    +L      CGLI   DA+RLC    NT L    S +   V+                    + H C G+ Q    P  Y    S CI+C+ C ++F    FV H+H + +   T HWGF S  W  ++ +         ++ AT      + A LK+ ++ MK K  +R   L   +P + T +V 
Sbjct:  162 LEGETISCFSVGGELRLCLPQVLNTVLRDFSLHQINSVCDQLYLYCSRCDASQLQVLKILGVLPPGAPSCGLITLTDAQRLC----NTLLHPGESNAPAGVLKGHSVGEDEEKEAEEGGAFWVEHQCLGKCQGLFVPRFYASPGSPCIRCSQCRRLFCPERFVMHSHWQPDK-RTCHWGFDSAKWACYLQLG------RRYQGAT------EEARLKQLLETMKMK--FRGIPLEAKLPHLETAQVQ 389

[Close]

BLAST of c-SKI_SMAD_bind domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001301.1 (pep scaffold:Pmarinus_7.0:GL481803:9978:11426:-1 gene:ENSPMAG00000001172.1 transcript:ENSPMAT00000001301.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 66.6254 bits (161), Expect = 3.516e-12
Identity = 37/144 (25.69%), Postives = 65/144 (45.14%), Query Frame = 3

Query:  111 LISFANGSNIKILMPHLIRSFFQDIDYPTINQLLTFLSIKCCQCTPEQLRILHTTKILSSDVNQCGLIDKVDAKRLCK-FIHNTNLTSIRSTSSLFVIPIIHYCFGRQQAFLYPDLYVKSNSRCIKCASCSQIFTTCEFVKHTH 539
            ++S       ++ +  +  +  +   Y  I+     L I C QCTP QL +L     +     +CG+I + +A+RLCK F+ +     +      F   + H C    +    P  Y  S ++CIKC+ C   F+  +F+ H+H
Sbjct:   18 IVSLVIDGQERLCLAQISNTLLKSYSYNEIHNRRVALGITCVQCTPVQLELLRRAGAMPVSSRRCGMITRREAERLCKSFLGDHEPPRLPEN---FAFDVTHECAWGCRGSFVPARYNSSRAKCIKCSLCGLFFSPNKFIFHSH 158

[Close]

BLAST of c-SKI_SMAD_bind domain-containing protein vs. Ensembl Nematostella
Match: EDO41836 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S373])

HSP 1 Score: 83.9593 bits (206), Expect = 3.457e-19
Identity = 48/160 (30.00%), Postives = 73/160 (45.62%), Query Frame = 3

Query:  141 KILMPHLIRSFFQDIDYPTINQLLTFLSIKCCQCTPEQLRILHTTKILSSDVNQCGLIDKVDAKRLCKFIHNTNLTSIRSTSSLFVI---PIIHYCFGRQQAFLYPDLYVKSNSRCIKCASCSQIFTTCEFVKHTHLKINHINTVHWGFHSLNWRYFIYI 611
            ++    L+    +      IN     L I C +CTP+QL +L    +L       GLI K DA RL   +  +N+      S LF +    + H CFG     L  +LY    + C+ C+ C  +F+   FV H H     ++T HWGF S NW+ ++ +
Sbjct:    4 RLCYKELVEKILKGFSSQVINATRDRLQIFCPRCTPQQLEVLKLAGVLPWSCASAGLIAKSDAFRLIGALTGSNVP--HRNSRLFSVDSLEVYHECFGGCVGTLEIELYTDPYAECVTCSQCDGVFSPRTFVTHHHTS-GEVHTCHWGFDSANWKLYLML 160

[Close]

BLAST of c-SKI_SMAD_bind domain-containing protein vs. Ensembl Medaka
Match: skib (ski oncogene [Source:NCBI gene;Acc:101171238])

HSP 1 Score: 121.324 bits (303), Expect = 3.691e-29
Identity = 66/207 (31.88%), Postives = 99/207 (47.83%), Query Frame = 3

Query:   90 TELENHFLISFANGSNIKILMPHLIRSFFQDIDYPTINQLLTFLSIKCCQCTPEQLRILHTTKILSSDVNQCGLIDKVDAKRLCKFI--------H-NTNLTSIRSTSSLFVIPIIHYCFGRQQAFLYPDLYVKSNSRCIKCASCSQIFTTCEFVKHTHLKINHINTVHWGFHSLNWRYFIYIYIFNADVEYHKNATLILDNIKSAF 683
            T LE   +  F  G   ++ +P ++ S  +D     IN +   L I C +CT +QL IL    IL      CGLI + DA+RLC  +        H N +L S+    +     + H CFGR +    P+LY    + CI+C  C  +F   +FV H+H ++ +  TVHWGF S NWR ++ +     D E   +   +L  +K  F
Sbjct:   81 TVLEREPISCFVVGGEKRLCLPQILNSVLRDFSLQQINSVCDDLHIYCSRCTADQLEILKVVGILPFSAPSCGLITQTDAERLCNALIYGGTYPPHCNKDLGSLELERTERSFKVYHECFGRCKGLFVPELYSSPAAACIQCMDCRLMFPPHKFVVHSHKRLEN-RTVHWGFDSSNWRVYVLLDADYTDKEEKSHLEQLLKELKGKF 286

[Close]

BLAST of c-SKI_SMAD_bind domain-containing protein vs. Ensembl Medaka
Match: skia (SKI proto-oncogene [Source:NCBI gene;Acc:101164645])

HSP 1 Score: 120.553 bits (301), Expect = 6.216e-29
Identity = 68/212 (32.08%), Postives = 96/212 (45.28%), Query Frame = 3

Query:   90 TELENHFLISFANGSNIKILMPHLIRSFFQDIDYPTINQLLTFLSIKCCQCTPEQLRILHTTKILSSDVNQCGLIDKVDAKRLC--------------KFIHNTNLTSIRSTSSLFVIPIIHYCFGRQQAFLYPDLYVKSNSRCIKCASCSQIFTTCEFVKHTHLKINHINTVHWGFHSLNWRYFIYIYIFNADVEYHKNATLILDNIKSAF 683
            T LE   +  F  G   ++ +P ++ +  +D     IN +   L I C +CT +QL IL    IL      CGLI K DA+RLC              K +       ++ T   F   + H CFG+ +  L P+LY   ++ CI+C  C  ++ T +FV H+H K     T HWGF S NWR +I +       E       ILD IK  F
Sbjct:   82 TVLEGETISCFVVGGEKRLCLPQILNTVLRDFSLQQINSVCDELHIYCSRCTADQLEILKVMGILPFSAPSCGLITKTDAERLCNALIYGGAFPPRAKKELGGAGALELQLTDRSFK--VYHECFGKCKGLLVPELYGSPSAACIQCLDCRLMYPTHKFVVHSH-KAQENRTCHWGFDSANWRAYILLSQDYTGKEEKARLEQILDEIKEKF 290

[Close]

BLAST of c-SKI_SMAD_bind domain-containing protein vs. Ensembl Medaka
Match: skia (SKI proto-oncogene [Source:NCBI gene;Acc:101164645])

HSP 1 Score: 120.553 bits (301), Expect = 6.482e-29
Identity = 68/212 (32.08%), Postives = 96/212 (45.28%), Query Frame = 3

Query:   90 TELENHFLISFANGSNIKILMPHLIRSFFQDIDYPTINQLLTFLSIKCCQCTPEQLRILHTTKILSSDVNQCGLIDKVDAKRLC--------------KFIHNTNLTSIRSTSSLFVIPIIHYCFGRQQAFLYPDLYVKSNSRCIKCASCSQIFTTCEFVKHTHLKINHINTVHWGFHSLNWRYFIYIYIFNADVEYHKNATLILDNIKSAF 683
            T LE   +  F  G   ++ +P ++ +  +D     IN +   L I C +CT +QL IL    IL      CGLI K DA+RLC              K +       ++ T   F   + H CFG+ +  L P+LY   ++ CI+C  C  ++ T +FV H+H K     T HWGF S NWR +I +       E       ILD IK  F
Sbjct:   82 TVLEGETISCFVVGGEKRLCLPQILNTVLRDFSLQQINSVCDELHIYCSRCTADQLEILKVMGILPFSAPSCGLITKTDAERLCNALIYGGAFPPRAKKELGGAGALELQLTDRSFK--VYHECFGKCKGLLVPELYGSPSAACIQCLDCRLMYPTHKFVVHSH-KAQENRTCHWGFDSANWRAYILLSQDYTGKEEKARLEQILDEIKEKF 290

[Close]

BLAST of c-SKI_SMAD_bind domain-containing protein vs. Ensembl Medaka
Match: skila (SKI like proto-oncogene [Source:NCBI gene;Acc:111949033])

HSP 1 Score: 103.605 bits (257), Expect = 2.764e-23
Identity = 58/206 (28.16%), Postives = 89/206 (43.20%), Query Frame = 3

Query:   96 LENHFLISFANGSNIKILMPHLIRSFFQDIDYPTINQLLTFLSIKCCQCTPEQLRILHTTKILSSDVNQCGLIDKVDAKRLCKFI----------HNTNLTSIRSTSSLFVIPIIHYCFGRQQAFLYPDLYVKSNSRCIKCASCSQIFTTCEFVKHTHLKINHINTVHWGFHSLNWRYFIYIYIFNADVEYHKNATLILDNIKSAF 683
            LE   +  F  G   ++ +P ++ S  +D     IN +   L + C +C  EQL IL    IL  +   CGLI   DA+RLC  +           +  L+ ++ + + F   + H C G  Q    P  Y +  + CI+C  C  +F+   FV H+H K     T HWGF S  W  ++ +              L+LD +K  F
Sbjct:  152 LEGESISCFVVGGEKRLCLPQVLNSVLRDFSLQQINTVCDELYVYCSRCDAEQLHILKVLGILPFNAPSCGLITLTDAQRLCNALLRPGAVLPPDPSGKLSVLKESETSFQ--VEHQCLGMCQGLFAPQFYSQPEAPCIQCVECQLLFSPQTFVMHSH-KSPDKRTCHWGFDSAKWPCYLQLARKYQGTAEEPKLKLLLDEVKEKF 354

[Close]

BLAST of c-SKI_SMAD_bind domain-containing protein vs. Ensembl Medaka
Match: skor1b (SKI family transcriptional corepressor 1 [Source:NCBI gene;Acc:101171078])

HSP 1 Score: 69.707 bits (169), Expect = 2.781e-12
Identity = 41/144 (28.47%), Postives = 70/144 (48.61%), Query Frame = 3

Query:  111 LISFANGSNIKILMPHLIRSFFQDIDYPTINQLLTFLSIKCCQCTPEQLRILHTTKILSSDVNQCGLIDKVDAKRLCKFIHNTNLTSIRSTSSLFVIPIIHYC-FGRQQAFLYPDLYVKSNSRCIKCASCSQIFTTCEFVKHTH 539
            ++S       ++ +  +  +  ++  Y  I+     L I C QCTP QL IL     +     +CG+I K +A+RLCK     +  S       F   + H C +G + +F+ P  Y  S ++CIKC+ C+  F+  +F+ H+H
Sbjct:   56 IVSLVIDGQERLCLAQISNTLLKNYSYNEIHNRRVALGITCVQCTPVQLEILRRAGAMPISSRRCGMITKREAERLCKSFLGAH--SPPKLPENFAFDVSHECAWGSRGSFI-PARYNSSRAKCIKCSYCNMYFSPNKFIFHSH 196

[Close]

BLAST of c-SKI_SMAD_bind domain-containing protein vs. Planmine SMEST
Match: SMESG000070642.1 (SMESG000070642.1)

HSP 1 Score: 792.727 bits (2046), Expect = 0.000e+0
Identity = 412/413 (99.76%), Postives = 413/413 (100.00%), Query Frame = 3

Query:   66 MESKIIQLTELENHFLISFANGSNIKILMPHLIRSFFQDIDYPTINQLLTFLSIKCCQCTPEQLRILHTTKILSSDVNQCGLIDKVDAKRLCKFIHNTNLTSIRSTSSLFVIPIIHYCFGRQQAFLYPDLYVKSNSRCIKCASCSQIFTTCEFVKHTHLKINHINTVHWGFHSLNWRYFIYIYIFNADVEYHKNATLILDNIKSAFLKEDMKKMKNKLPWRPKNLRINIPPISTNKVNSIFQEMKPIFKRKDVIRSNTDQITFIPNVYIDSKDNXXXXXXXXXXXXXXXXXXXXXXNKESKLNSLANISEERLNILQKINEYKRIISTEKSKNYLGRHSTKFCNRKFQPKYILLSRFQKNESDKMETEIGPSTNKCTYEMSFHIRNQLHKSVFEKLNYLMQITEQRKQRKSAR 1304
            MESKIIQLTELENHFLISFANGSNIKILMPHLIRSFFQDIDYPTINQLLTFLSIKCCQCTPEQLRILHTTKILSSDVNQCGLIDKVDAKRLCKFIHNTNLTSIRSTSSLFVIPIIHYCFGRQQAFLYPDLYVKSNSRCIKCASCSQIFTTCEFVKHTHLKINHINTVHWGFHSLNWRYFIYIYIFNADVEYHKNATLILDNIKSAFLKEDMKKMKNKLPWRPKNLRINIPPISTNKVNSIFQEMKPIFKRKDVIRSNTDQITFIPNVYIDSKDNLSCDSLTDSVLDDDDDEYEDLSNKESKLNSLANISEERLNILQKINEYKRIISTEKSKNYLGRHSTKFCNRKFQPKYILLSRFQKNES+KMETEIGPSTNKCTYEMSFHIRNQLHKSVFEKLNYLMQITEQRKQRKSAR
Sbjct:    1 MESKIIQLTELENHFLISFANGSNIKILMPHLIRSFFQDIDYPTINQLLTFLSIKCCQCTPEQLRILHTTKILSSDVNQCGLIDKVDAKRLCKFIHNTNLTSIRSTSSLFVIPIIHYCFGRQQAFLYPDLYVKSNSRCIKCASCSQIFTTCEFVKHTHLKINHINTVHWGFHSLNWRYFIYIYIFNADVEYHKNATLILDNIKSAFLKEDMKKMKNKLPWRPKNLRINIPPISTNKVNSIFQEMKPIFKRKDVIRSNTDQITFIPNVYIDSKDNLSCDSLTDSVLDDDDDEYEDLSNKESKLNSLANISEERLNILQKINEYKRIISTEKSKNYLGRHSTKFCNRKFQPKYILLSRFQKNESEKMETEIGPSTNKCTYEMSFHIRNQLHKSVFEKLNYLMQITEQRKQRKSAR 413

[Close]

BLAST of c-SKI_SMAD_bind domain-containing protein vs. Planmine SMEST
Match: SMESG000018825.1 (SMESG000018825.1)

HSP 1 Score: 168.318 bits (425), Expect = 5.843e-46
Identity = 106/291 (36.43%), Postives = 155/291 (53.26%), Query Frame = 3

Query:   96 LENHFLISFANGSNIKILMPHLIRSFFQDIDYPTINQLLTFLSIKCCQCTPEQLRILHTTKILSSDVNQCGLIDKVDAKRLCKFIH--NTNLTSIRST----SSLFVIPIIHYCFGRQQAFLYPDLYVKSNSRCIKCASCSQIFTTCEFVKHTHLKINHI-NTVHWGFHSLNWRYFIYIYI--FNADVEYHKNATLILDNIKSAFLKEDMKKMKN---KLPWRP-KNLRINIPPISTNKVNSIFQEMKPIFKR---KDVIRSNT---------DQIT---FIPNVYIDSKD 884
            +EN  +  F      +I +P L+R    + D   I+Q +T L I C QC  +Q+++LH  +I    + +CGLI K DA+RLCK++   N N ++I  T    S    I ++H CFG Q+  LYP LY  S+++CIKCA+C   F T EFV HTH K++ + NT HWGF S NWR  + IY    N +VE   +   ILD +K+ + ++++KK       L WRP +  ++  PP    K N  F   KP   R    DV R  +         D+++   F+PNVY+   D
Sbjct:    2 IENELIAGFNVWGERRICLPQLLRFVLPEFDINVIDQAVTDLRINCFQCNNQQIKMLHDNEIFPKHIVRCGLIRKSDAERLCKYLFQPNQNYSTISETNQKLSQQESIQVVHTCFGEQRGILYPVLYNSSDAKCIKCATCENFFKTFEFVGHTH-KLDEVSNTFHWGFDSNNWRLLLQIYTDPENGNVEMLNDKKSILDKVKALYYEDEIKKRNQTNINLVWRPSRKFKLPNPP----KPN--FNSPKPPHLRDGLADVYRKTSNSSLNVSKFDKLSNNNFVPNVYLQPPD 285

[Close]

BLAST of c-SKI_SMAD_bind domain-containing protein vs. Planmine SMEST
Match: SMESG000067290.1 (SMESG000067290.1)

HSP 1 Score: 114.775 bits (286), Expect = 1.962e-27
Identity = 61/194 (31.44%), Postives = 101/194 (52.06%), Query Frame = 3

Query:   90 TELENHFLISFANGSNIKILMPHLIRSFFQDIDYPTINQLLTFLSIKCCQCTPEQLRILHTTKILSSDVNQCGLIDKVDAKRLCKFI-------------HNTNLTSIRSTSSLFV---IPIIHYCFGRQQAFLYPDLYVKSNSRCIKCASCSQIFTTCEFVKHTHL----KINHINTVHWGFHSLNWRYFIYI 611
            T L   ++ SF N     + +P ++ +  ++ID   IN+ +  + I C +C  E+L +LH   IL   V  CGLI + +A+R+ KF              +N  +TS + TS       I + H CFG+Q+  ++P  Y  +N++CI+C  CS++ +  +FV HTH     K +     HWGF S NWR+++ +
Sbjct:  116 TLLNKTYIASFNNDGEKLLCLPQIL-NLLKNIDISDINEAINSMGIICTECDEERLSVLHKHNILPKQVTCCGLISQSNAERMLKFFTSIGIDINSSEMNNNNTITSDKITSDSAAYHQIRVTHDCFGQQKGIIFPLKYTHANAQCIECLECSKMMSPSDFVGHTHQEFGSKWSETEVCHWGFDSSNWRWYLRL 308

[Close]

BLAST of c-SKI_SMAD_bind domain-containing protein vs. Planmine SMEST
Match: SMESG000002232.1 (SMESG000002232.1)

HSP 1 Score: 88.5817 bits (218), Expect = 1.746e-19
Identity = 60/191 (31.41%), Postives = 96/191 (50.26%), Query Frame = 3

Query:  162 IRSFFQDIDYPTINQLLTFLSIKCCQCTPEQLRILHTTKILSSDVNQCGLIDKVDAKRLCKFIHNTN-----LTSIRSTSSLFVIPIIHYCFGR---QQAFLYPDLYVKSNSRCIKCASCSQIFTTCEFVKHTHLKINHINTVHWGFHSLNWRYFIYIYI--FNADVEYHKNATLILDNIKSAFLKEDMKK 704
            +R    + D+  I+Q++T L I C QC  +Q+++L   +I    + +CG+I K DA+RLCK++   N     +T   +  + F +      F R    +  LYP LY  S+++CIKCA       T E            NT  WGF S NWR  + IY    N +VE   +   +LD +K+ + ++++KK
Sbjct:    1 MRLTLPEFDFNVIDQVVTDLRINCFQCNNQQIKMLRDNEIFLKHIVRCGIIRKSDAERLCKYLFQPNQNYSTITKCLANKNRFRL------FTRVLENKVVLYPVLYSSSDAKCIKCA-------TYEVS----------NTFRWGFDSNNWRLLLQIYTDPENGNVEMINDMKSVLDKVKALYYEDEIKK 168

[Close]

BLAST of c-SKI_SMAD_bind domain-containing protein vs. Planmine SMEST
Match: SMESG000037051.1 (SMESG000037051.1)

HSP 1 Score: 80.8777 bits (198), Expect = 7.470e-18
Identity = 57/169 (33.73%), Postives = 84/169 (49.70%), Query Frame = 3

Query:  303 CGLIDKVDAKRLCKFIHNTNLTSIRSTSSLFVIPIIHYCFGRQQAFLYPDLYVKSNSRCIKCASCSQIFTTCEFVKHTHLKINHI-NTVHWGFHSLNWRYFIYIYI--FNADVEYHKNATLILDNIKSAFLKEDMKKMKNKLPWRPKNLRINIPPISTNKVNSIFQEMK 800
            CG I K D +  CK+     L  + + + L    + H   G Q+  L+P LY  S+++CI CA C  +F T EF+ HTH K++ + NT HWGF S NWR  + +Y+   NA VE       +L+++KS   K  M K +        +  +N   +  NKV      MK
Sbjct:   13 CGPIRKSDTECSCKY-----LPLLSNPTKLQQNQVAHPYPGEQRGVLHPMLYNSSDAKCINCAMCENLFKTFEFIDHTH-KLDEVSNTFHWGFCSNNWRLLLQVYVDPENAIVE-------VLNDMKSILQKTAMMKCEVTFTENGNDEMLNDMKLILNKVKYCITRMK 168

The following BLAST results are available for this feature:

BLAST of c-SKI_SMAD_bind domain-containing protein vs. Ensembl Human
BLAST of c-SKI_SMAD_bind domain-containing protein vs. Ensembl Celegans
BLAST of c-SKI_SMAD_bind domain-containing protein vs. Ensembl Fly
BLAST of c-SKI_SMAD_bind domain-containing protein vs. Ensembl Zebrafish
BLAST of c-SKI_SMAD_bind domain-containing protein vs. Ensembl Xenopus
BLAST of c-SKI_SMAD_bind domain-containing protein vs. Ensembl Mouse
BLAST of c-SKI_SMAD_bind domain-containing protein vs. UniProt/SwissProt
BLAST of c-SKI_SMAD_bind domain-containing protein vs. TrEMBL
BLAST of c-SKI_SMAD_bind domain-containing protein vs. Ensembl Cavefish
BLAST of c-SKI_SMAD_bind domain-containing protein vs. Ensembl Sea Lamprey
BLAST of c-SKI_SMAD_bind domain-containing protein vs. Ensembl Yeast
BLAST of c-SKI_SMAD_bind domain-containing protein vs. Ensembl Nematostella
BLAST of c-SKI_SMAD_bind domain-containing protein vs. Ensembl Medaka
BLAST of c-SKI_SMAD_bind domain-containing protein vs. Planmine SMEST

BLAST of c-SKI_SMAD_bind domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
SKI	9.504e-27	30.00	SKI proto-oncogene [Source:HGNC Symbol;Acc:HGNC:10...	[more]
SKIL	2.916e-25	29.15	SKI like proto-oncogene [Source:HGNC Symbol;Acc:HG...	[more]
SKIL	2.916e-25	29.15	SKI like proto-oncogene [Source:HGNC Symbol;Acc:HG...	[more]
SKIL	2.982e-25	29.15	SKI like proto-oncogene [Source:HGNC Symbol;Acc:HG...	[more]
SKIL	3.175e-25	29.15	SKI like proto-oncogene [Source:HGNC Symbol;Acc:HG...	[more]

BLAST of c-SKI_SMAD_bind domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of c-SKI_SMAD_bind domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Snoo	4.889e-32	35.19	gene:FBgn0085450 transcript:FBtr0343409	[more]
Snoo	4.889e-32	35.19	gene:FBgn0085450 transcript:FBtr0112717	[more]
Snoo	4.889e-32	35.19	gene:FBgn0085450 transcript:FBtr0112719	[more]
Snoo	4.889e-32	35.19	gene:FBgn0085450 transcript:FBtr0112718	[more]
fuss	1.099e-12	31.34	gene:FBgn0039932 transcript:FBtr0301336	[more]

BLAST of c-SKI_SMAD_bind domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
skia	3.599e-29	31.73	v-ski avian sarcoma viral oncogene homolog a [Sour...	[more]
skib	1.162e-27	32.70	v-ski avian sarcoma viral oncogene homolog b [Sour...	[more]
skilb	4.130e-24	26.85	SKI-like proto-oncogene b [Source:ZFIN;Acc:ZDB-GEN...	[more]
skilb	4.130e-24	26.85	SKI-like proto-oncogene b [Source:ZFIN;Acc:ZDB-GEN...	[more]
skila	1.281e-23	27.75	SKI-like proto-oncogene a [Source:ZFIN;Acc:ZDB-GEN...	[more]

BLAST of c-SKI_SMAD_bind domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ENSXETT00000042147.1	2.056e-26	30.14	SKI-like proto-oncogene [Source:NCBI gene;Acc:1004...	[more]
SKI	3.132e-25	28.77	SKI proto-oncogene [Source:NCBI gene;Acc:100486949...	[more]
arg1	1.410e-12	27.27	arginase 1 [Source:Xenbase;Acc:XB-GENE-966913]	[more]
SKOR1	2.669e-12	26.11	SKI family transcriptional corepressor 1 [Source:N...	[more]
SKOR1	2.840e-12	26.11	SKI family transcriptional corepressor 1 [Source:N...	[more]

BLAST of c-SKI_SMAD_bind domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Ski	2.595e-28	28.52	ski sarcoma viral oncogene homolog (avian) [Source...	[more]
Ski	8.323e-28	28.06	ski sarcoma viral oncogene homolog (avian) [Source...	[more]
Skil	1.949e-26	29.15	SKI-like [Source:MGI Symbol;Acc:MGI:106203]	[more]
Skil	3.523e-26	29.15	SKI-like [Source:MGI Symbol;Acc:MGI:106203]	[more]
Skil	4.690e-26	29.15	SKI-like [Source:MGI Symbol;Acc:MGI:106203]	[more]

BLAST of c-SKI_SMAD_bind domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q60698\|SKI_MOUSE	1.696e-27	28.52	Ski oncogene OS=Mus musculus OX=10090 GN=Ski PE=1 ...	[more]
sp\|P12755\|SKI_HUMAN	4.564e-26	30.00	Ski oncogene OS=Homo sapiens OX=9606 GN=SKI PE=1 S...	[more]
sp\|P17863\|SKI_AVIES	9.351e-26	29.67	Transforming protein Ski OS=Avian erythroblastosis...	[more]
sp\|Q9TUG2\|SKI_HORSE	1.907e-25	28.81	Ski oncogene OS=Equus caballus OX=9796 GN=SKI PE=2...	[more]
sp\|P49140\|SKI_CHICK	1.917e-25	30.29	Ski oncogene OS=Gallus gallus OX=9031 GN=SKI PE=1 ...	[more]

BLAST of c-SKI_SMAD_bind domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A1Y1MFT2	2.527e-33	37.69	c-SKI_SMAD_bind domain-containing protein OS=Photi...	[more]
A0A482VDX3	3.225e-33	32.48	Ski Sno and/or c-SKI SMAD bind domain containing p...	[more]
A0A1Z5LAJ0	1.433e-32	29.17	Transforming protein Ski (Fragment) OS=Ornithodoro...	[more]
A0A1B6GH89	3.102e-32	33.96	c-SKI_SMAD_bind domain-containing protein (Fragmen...	[more]
A0A484B881	4.583e-32	33.93	c-SKI_SMAD_bind domain-containing protein OS=Droso...	[more]

BLAST of c-SKI_SMAD_bind domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
skib	1.704e-30	31.71	ski oncogene-like [Source:NCBI gene;Acc:103031474]	[more]
skib	2.629e-30	31.71	ski oncogene-like [Source:NCBI gene;Acc:103031474]	[more]
skia	1.331e-27	31.18	ski oncogene [Source:NCBI gene;Acc:103046211]	[more]
skila	3.477e-24	27.23	SKI like proto-oncogene [Source:NCBI gene;Acc:1030...	[more]
skilb	6.275e-22	26.32	ski-like protein [Source:NCBI gene;Acc:103027845]	[more]

BLAST of c-SKI_SMAD_bind domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1


Match Name	E-value	Identity	Description
ENSPMAT00000001301.1	3.516e-12	25.69	pep scaffold:Pmarinus_7.0:GL481803:9978:11426:-1 g...	[more]

BLAST of c-SKI_SMAD_bind domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of c-SKI_SMAD_bind domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1


Match Name	E-value	Identity	Description
EDO41836	3.457e-19	30.00	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of c-SKI_SMAD_bind domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
skib	3.691e-29	31.88	ski oncogene [Source:NCBI gene;Acc:101171238]	[more]
skia	6.216e-29	32.08	SKI proto-oncogene [Source:NCBI gene;Acc:101164645...	[more]
skia	6.482e-29	32.08	SKI proto-oncogene [Source:NCBI gene;Acc:101164645...	[more]
skila	2.764e-23	28.16	SKI like proto-oncogene [Source:NCBI gene;Acc:1119...	[more]
skor1b	2.781e-12	28.47	SKI family transcriptional corepressor 1 [Source:N...	[more]

BLAST of c-SKI_SMAD_bind domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000070642.1	0.000e+0	99.76	SMESG000070642.1	[more]
SMESG000018825.1	5.843e-46	36.43	SMESG000018825.1	[more]
SMESG000067290.1	1.962e-27	31.44	SMESG000067290.1	[more]
SMESG000002232.1	1.746e-19	31.41	SMESG000002232.1	[more]
SMESG000037051.1	7.470e-18	33.73	SMESG000037051.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30017315 ID=SMED30017315|Name=c-SKI_SMAD_bind domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=1314bp
GAAAAATATCATATCTATTAGTATTTTATATTCATAATATATTACTTAAA
ATATAAAGCTTACTAATGGAATCAAAAATAATCCAACTAACTGAACTGGA
AAATCATTTCCTCATCTCTTTTGCAAATGGATCTAATATCAAAATCCTCA
TGCCACATCTAATAAGATCTTTCTTTCAAGACATAGATTATCCAACAATA
AACCAACTACTAACGTTTCTTAGTATCAAATGTTGTCAATGTACCCCAGA
ACAACTTCGAATTCTTCATACAACAAAGATTCTCTCATCCGATGTCAACC
AGTGTGGTCTTATTGACAAAGTCGATGCAAAGAGACTGTGTAAATTTATC
CATAACACCAATCTCACCTCTATTAGATCTACTTCATCTTTATTTGTCAT
ACCGATTATACATTATTGTTTTGGAAGACAACAAGCATTTCTTTATCCCG
ACCTCTACGTGAAATCGAATTCAAGATGTATAAAATGTGCCTCGTGTTCT
CAGATCTTTACCACCTGTGAGTTCGTCAAACATACCCATTTGAAAATTAA
TCATATCAACACTGTACATTGGGGATTTCATTCACTAAATTGGAGATATT
TTATTTACATATACATTTTCAATGCCGACGTAGAGTACCACAAAAATGCG
ACACTAATATTAGATAACATCAAATCTGCCTTTCTCAAAGAAGACATGAA
AAAAATGAAAAATAAATTACCCTGGAGACCGAAAAATTTAAGAATCAACA
TTCCACCTATTTCTACAAACAAAGTAAATTCAATTTTTCAAGAAATGAAA
CCTATTTTCAAAAGAAAAGACGTCATCAGATCAAACACAGATCAAATAAC
ATTTATACCGAATGTTTATATTGACTCGAAAGACAATTTAAGTTGTGATT
CTCTCACAGATTCGGTTCTTGATGACGATGATGATGAATATGAAGATCTG
TCAAATAAAGAATCAAAATTGAATTCACTGGCAAACATATCAGAGGAAAG
ATTAAATATTTTACAAAAGATAAATGAATACAAAAGAATCATATCAACAG
AAAAATCAAAAAATTATTTAGGAAGGCATTCTACAAAGTTCTGCAACCGG
AAATTTCAACCAAAATATATCCTTTTATCAAGATTTCAAAAAAATGAATC
AGATAAAATGGAAACTGAGATTGGGCCGTCGACAAATAAATGTACCTACG
AAATGAGTTTCCACATTCGAAATCAACTGCATAAATCAGTTTTCGAAAAA
CTGAACTATTTAATGCAAATTACGGAGCAGCGAAAACAGAGAAAAAGTGC
TCGATAAAATTTAG

protein sequence of SMED30017315-orf-1

>SMED30017315-orf-1 ID=SMED30017315-orf-1|Name=SMED30017315-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=414bp
MESKIIQLTELENHFLISFANGSNIKILMPHLIRSFFQDIDYPTINQLLT
FLSIKCCQCTPEQLRILHTTKILSSDVNQCGLIDKVDAKRLCKFIHNTNL
TSIRSTSSLFVIPIIHYCFGRQQAFLYPDLYVKSNSRCIKCASCSQIFTT
CEFVKHTHLKINHINTVHWGFHSLNWRYFIYIYIFNADVEYHKNATLILD
NIKSAFLKEDMKKMKNKLPWRPKNLRINIPPISTNKVNSIFQEMKPIFKR
KDVIRSNTDQITFIPNVYIDSKDNLSCDSLTDSVLDDDDDEYEDLSNKES
KLNSLANISEERLNILQKINEYKRIISTEKSKNYLGRHSTKFCNRKFQPK
YILLSRFQKNESDKMETEIGPSTNKCTYEMSFHIRNQLHKSVFEKLNYLM
QITEQRKQRKSAR*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000099	neuron
PLANA:0000418	head

Vocabulary: **INTERPRO**
Term	Definition
IPR014890	c-SKI_SMAD4-bd_dom
IPR003380	SKI/SNO/DAC
IPR010919	SAND-like_dom_sf
IPR009061	DNA-bd_dom_put_sf

Vocabulary: **molecular function**
Term	Definition
GO:0046332	SMAD binding

Main menu

c-SKI_SMAD_bind domain-containing protein

Zeng et. al., 2018

▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 5

Owlery

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