Ig-like domain-containing protein

Overview


Name	Ig-like domain-containing protein
Smed ID	SMED30017278
Length (bp)	2231

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of Ig-like domain-containing protein (SMED30017278) t-SNE clustered cells

Violin plots show distribution of expression levels for Ig-like domain-containing protein (SMED30017278) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Ig-like domain-containing protein (SMED30017278) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Ig-like domain-containing protein (SMED30017278) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30017278

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 6

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
head region	SMED30017278	SMESG000001734.1	SmedASXL_011581	SmedAsxl_ww_GCZZ01	PMID:27034770 Currie et al., 2016
nervous system	SMED30017278	SMESG000001734.1	dd_Smed_v4_10042_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30017278	SMESG000001734.1	dd_Smed_v4_10042_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
neuron	SMED30017278	SMESG000001734.1	dd_Smed_v4_10042_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
head region	SMED30017278	SMESG000001734.1	dd_Smed_v6_10042_0_1	dd_Smed_v6	PMID:28171748 Stückemann et al., 2017
head region	SMED30017278	SMESG000001734.1	OX_Smed_1.0.13184	ox_Smed_v2	PMID:24238224 Kao et al., 2013

Note: Hover over icons to view figure legend

Homology

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BLAST of Ig-like domain-containing protein vs. Ensembl Human
Match: LRRC4B (leucine rich repeat containing 4B [Source:HGNC Symbol;Acc:HGNC:25042])

HSP 1 Score: 63.929 bits (154), Expect = 8.119e-10
Identity = 64/270 (23.70%), Postives = 110/270 (40.74%), Query Frame = 3

Query:  453 CSLQAIESRAFSQIIYLETLDLSFNKLTELEPFTFADL-NLKFLRLDGNLNLKLTANSFKELRVDXXXXXXXXXXXXPFTVLEPISTGLIQLILTSNRFTTLESRYETLFQRLSRFGLDDNRFDCSQCSLIWMANTMKAIYYKNQNKDQQTIIYPKCHQPYKLKDKFIHSLSSSDFQCPKPSIEK--ISIFILPNNTAQLICTASDVQSSVIWSQVFEPNDKDFLLIEQRKQILSNSAHSNKLVINK--NQDIDVFLCTVTSLIGNASST 1247
            C+L+ I +   + ++ LE L+LS N+L  + P +F  L +L+ L L       +  N+F +L+                         L +L L+ N   +L     T   RL R  L+ N + C+ C ++W++      ++  +     T    +CH P  LK ++I  L  S F C  P I +    + +     A+L C      +SV W     PN    L+     ++  +  H   L       QD   + C VT+  GN +++
Sbjct:  217 CNLKDIPN--LTALVRLEELELSGNRLDLIRPGSFQGLTSLRKLWLMHAQVATIERNAFDDLK------------------------SLEELNLSHNNLMSLPHDLFTPLHRLERVHLNHNPWHCN-CDVLWLS------WWLKETVPSNTTCCARCHAPAGLKGRYIGELDQSHFTCYAPVIVEPPTDLNVTEGMAAELKCRTGTSMTSVNW---LTPNGT--LMTHGSYRVRISVLHDGTLNFTNVTVQDTGQYTCMVTNSAGNTTAS 448

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Query:  453 CSLQAIESRAFSQIIYLETLDLSFNKLTELEPFTFADL-NLKFLRLDGNLNLKLTANSFKELRVDXXXXXXXXXXXXPFTVLEPISTGLIQLILTSNRFTTLESRYETLFQRLSRFGLDDNRFDCSQCSLIWMANTMKAIYYKNQNKDQQTIIYPKCHQPYKLKDKFIHSLSSSDFQCPKPSIEK--ISIFILPNNTAQLICTASDVQSSVIWSQVFEPNDKDFLLIEQRKQILSNSAHSNKLVINK--NQDIDVFLCTVTSLIGNASST 1247
            C+L+ I +   + ++ LE L+LS N+L  + P +F  L +L+ L L       +  N+F +L+                         L +L L+ N   +L     T   RL R  L+ N + C+ C ++W++      ++  +     T    +CH P  LK ++I  L  S F C  P I +    + +     A+L C      +SV W     PN    L+     ++  +  H   L       QD   + C VT+  GN +++
Sbjct:  217 CNLKDIPN--LTALVRLEELELSGNRLDLIRPGSFQGLTSLRKLWLMHAQVATIERNAFDDLK------------------------SLEELNLSHNNLMSLPHDLFTPLHRLERVHLNHNPWHCN-CDVLWLS------WWLKETVPSNTTCCARCHAPAGLKGRYIGELDQSHFTCYAPVIVEPPTDLNVTEGMAAELKCRTGTSMTSVNW---LTPNGT--LMTHGSYRVRISVLHDGTLNFTNVTVQDTGQYTCMVTNSAGNTTAS 448

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Query:  453 CSLQAIESRAFSQIIYLETLDLSFNKLTELEPFTFADL-NLKFLRLDGNLNLKLTANSFKELRVDXXXXXXXXXXXXPFTVLEPISTGLIQLILTSNRFTTLESRYETLFQRLSRFGLDDNRFDCSQCSLIWMANTMKAIYYKNQNKDQQTIIYPKCHQPYKLKDKFIHSLSSSDFQCPKPSIEK--ISIFILPNNTAQLICTASDVQSSVIWSQVFEPNDKDFLLIEQRKQILSNSAHSNKLVINK--NQDIDVFLCTVTSLIGNASST 1247
            C+L+ I +   + ++ LE L+LS N+L  + P +F  L +L+ L L       +  N+F +L+                         L +L L+ N   +L     T   RL R  L+ N + C+ C ++W++      ++  +     T    +CH P  LK ++I  L  S F C  P I +    + +     A+L C      +SV W     PN    L+     ++  +  H   L       QD   + C VT+  GN +++
Sbjct:  217 CNLKDIPN--LTALVRLEELELSGNRLDLIRPGSFQGLTSLRKLWLMHAQVATIERNAFDDLK------------------------SLEELNLSHNNLMSLPHDLFTPLHRLERVHLNHNPWHCN-CDVLWLS------WWLKETVPSNTTCCARCHAPAGLKGRYIGELDQSHFTCYAPVIVEPPTDLNVTEGMAAELKCRTGTSMTSVNW---LTPNGT--LMTHGSYRVRISVLHDGTLNFTNVTVQDTGQYTCMVTNSAGNTTAS 448

[Close]

BLAST of Ig-like domain-containing protein vs. Ensembl Human
Match: SLIT1 (slit guidance ligand 1 [Source:HGNC Symbol;Acc:HGNC:11085])

HSP 1 Score: 58.151 bits (139), Expect = 2.882e-8
Identity = 70/284 (24.65%), Postives = 114/284 (40.14%), Query Frame = 3

Query:  240 CPPVCNQMACNMGILTCSETGLSEIPKLIPPKTNKILLINQDFSEAGTLTRLNLSDYSSXXXXXXXXXXQNCSLQAIESRAFSQIIYLETLDLSFNKLTELEPFTFADLNLKFLRLDGNLNLKLT--------ANSFKELRVDXXXXXXXXXXXXPFTVLEPISTGLIQLILTSNRFTTLESRYETLFQRLSRFGLDDNRFDCSQCSLIWMANTMKAIYYKNQNKDQQTI-IYPKCHQPYKLKDKFIHSLSSSDFQC-PKPSIEKISIFILPNNTAQLICTASD 1061
            CP +C    C    + C  TGL  IPK IP  T ++ L          +TR++ +D++  K       ++N  + A+E  AF  +  LE L L+ N+L  L    F + N    RLD + N            A   K L++D   +         F  L     GL  L L +N  TT+         +L  F L  N   C  C L W++  +         + + TI ++ +C  P  L+   +  +  S+F C  +    ++    L + +   +CT S+
Sbjct:   34 CPALC---TCTGTTVDCHGTGLQAIPKNIPRNTERLEL------NGNNITRIHKNDFAGLKQLRVLQLMEN-QIGAVERGAFDDMKELERLRLNRNQLHMLPELLFQN-NQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGA--FRALR----GLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHLFC-DCHLAWLSQWL---------RQRPTIGLFTQCSGPASLRGLNVAEVQKSEFSCSGQGEAGRVPTCTLSSGSCPAMCTCSN 290

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BLAST of Ig-like domain-containing protein vs. Ensembl Human
Match: LRRC4C (leucine rich repeat containing 4C [Source:HGNC Symbol;Acc:HGNC:29317])

HSP 1 Score: 58.151 bits (139), Expect = 4.809e-8
Identity = 63/268 (23.51%), Postives = 112/268 (41.79%), Query Frame = 3

Query:  453 CSLQAIESRAFSQIIYLETLDLSFNKLTELEPFTFADL-NLKFLRLDGNLNLKLTANSFKELRVDXXXXXXXXXXXXPFTVLEPISTGLIQLILTSNRFTTLESRYETLFQRLSRFGLDDNRFDCSQCSLIWMANTMKAIYYKNQNKDQQTIIYPKCHQPYKLKDKFIHSLSSSDFQCPKPSIEK--ISIFILPNNTAQLICTASDVQSSVIWSQVFEPNDKDFLLIEQRKQILSNSAHSNKLVINKNQDIDVFLCTVTSLIGNASST 1247
            C+L+ I +   + +I L+ LDLS N L+ + P +F  L +L+ L +  +    +  N+F  L+                         L+++ L  N  T L     T    L R  L  N ++C+ C ++W++  +K +   N      T    +C+ P  LK ++I  L  + F C  P I +    + +     A+L C AS   +SV W     PN         + +I   S  +        QD  ++ C V++ +GN +++
Sbjct:  207 CNLREIPN--LTPLIKLDELDLSGNHLSAIRPGSFQGLMHLQKLWMIQSQIQVIERNAFDNLQ------------------------SLVEINLAHNNLTLLPHDLFTPLHHLERIHLHHNPWNCN-CDILWLSWWIKDMAPSN------TACCARCNTPPNLKGRYIGELDQNYFTCYAPVIVEPPADLNVTEGMAAELKCRASTSLTSVSW---ITPNGTVMTHGAYKVRIAVLSDGTLNFTNVTVQDTGMYTCMVSNSVGNTTAS 438

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BLAST of Ig-like domain-containing protein vs. Ensembl Celegans
Match: slt-1 (Slit homolog 1 protein [Source:UniProtKB/Swiss-Prot;Acc:G5EFX6])

HSP 1 Score: 50.0618 bits (118), Expect = 7.470e-6
Identity = 42/129 (32.56%), Postives = 62/129 (48.06%), Query Frame = 3

Query:  237 ICPPVCNQMACNMGILTCSETGLSEIPKLIPPKTNKILL----INQ----DFSEAGTLTRLNLSDYSSXXXXXXXXXXQNCSLQAIESRAFSQIIYLETLDLSFNKLTELEPFTFADLN-LKFLRLDGN 596
            +CPP C   +C   ++ CS   L+  P  IP  T ++ L    IN+    D +   +LT+L+LS                  L ++E+  FS +  L TL +S+NKL  L+P  F  LN L+ L L GN
Sbjct:  676 LCPPKC---SCLDRVVRCSNKNLTSFPSRIPFDTTELYLDANYINEIPAHDLNRLYSLTKLDLSHNR---------------LISLENNTFSNLTRLSTLIISYNKLRCLQPLAFNGLNALRILSLHGN 786

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BLAST of Ig-like domain-containing protein vs. Ensembl Fly
Match: sli (gene:FBgn0264089 transcript:FBtr0330734)

HSP 1 Score: 60.8474 bits (146), Expect = 5.150e-9
Identity = 75/314 (23.89%), Postives = 126/314 (40.13%), Query Frame = 3

Query:  240 CPPVCNQMACNMGILTCSETGLSEIPKLIPPKTNKILLINQDFSEAGTLTRLNLSDYSSXXXXXXXXXXQNCSLQAIESRAFSQIIYLETLDLSFNKLTELEPFTFADLNLKFLRLDGNLNLKLT--------ANSFKELRVDXXXXXXXXXXXXPFTVLEPIS-TGLIQL---ILTSNRFTTLESRYETLFQRLSRFGLDDNRFDCSQCSLIWMANTMKAIYYKNQNKDQQTIIYPKCHQPYKLKDKFIHSLSSSDFQCPKPSIEKISIFILPNNTAQLICTASDV-----QSSVIWSQVFEPNDKDFLLIEQ 1130
            CP VC+    N   + CS  GL+ +P+ I     ++ L      +   LT +  +D+             N  +  IE  +F  ++ LE L L+ N+L  + P  F   +   LRLD + N+  T        A S + L++D+             T L+  +  GL++L    L +N  T+L         RL    L DN F C  C L W++  +++          +   Y +C  P +LK + +  L   +F+C   + E   +     N+    C  +D      + S+    V  P+D   L +EQ
Sbjct:   73 CPRVCSCTGLN---VDCSHRGLTSVPRKISADVERLEL------QGNNLTVIYETDFQRLTKLRMLQLTDN-QIHTIERNSFQDLVSLERLRLNNNRLKAI-PENFVTSSASLLRLDISNNVITTVGRRVFKGAQSLRSLQLDNNQ----------ITCLDEHAFKGLVELEILTLNNNNLTSLPHNIFGGLGRLRALRLSDNPFACD-CHLSWLSRFLRSA--------TRLAPYTRCQSPSQLKGQNVADLHDQEFKCSGLT-EHAPMECGAENSCPHPCRCADGIVDCREKSLTSVPVTLPDDTTELRLEQ 355

HSP 2 Score: 54.6842 bits (130), Expect = 3.442e-7
Identity = 62/257 (24.12%), Postives = 96/257 (37.35%), Query Frame = 3

Query:  240 CPPVCNQMACNMGILTCSETGLSEIPKLIPPKTNKILLINQDFSEAG--------TLTRLNLSDYSSXXXXXXXXXXQNCSLQAIESRAFSQIIYLETLDLSFNKLTELEPFTFADL-NLKFLRLDGNLNLKLTANSFKELRVDXXXXXXXXXXXXPFTVLEPISTGLIQLILTSNRFTTLESRYETLFQRLSRFGLDDNRFDCSQCSLIWMANTMKAIYYKNQNKDQQTIIYPKCHQPYKLKDKFIHSLSSSDFQC 983
            CPP C    C   ++ CS   L EIP+ IP +T+++ L + +  +          +LTRL+LS               N  +  + +  F+ +  L TL +S+NKL  L+    + L NL+ L L GN    L   SF++L+                                                 L+   L  N   C  C L W ++ +K  Y +            +C +P ++KDK I S  SS F C
Sbjct:  739 CPPSC---TCTGTVVRCSRNQLKEIPRGIPAETSELYLESNEIEQIHYERIRHLRSLTRLDLS---------------NNQITILSNYTFANLTKLSTLIISYNKLQCLQRHALSGLNNLRVLSLHGNRISMLPEGSFEDLKS------------------------------------------------LTHIALGSNPLYCD-CGLKWFSDWIKLDYVEPG--------IARCAEPEQMKDKLILSTPSSSFVC 920

[Close]

BLAST of Ig-like domain-containing protein vs. Ensembl Fly
Match: sli (gene:FBgn0264089 transcript:FBtr0330733)

HSP 1 Score: 60.4622 bits (145), Expect = 6.077e-9
Identity = 76/314 (24.20%), Postives = 125/314 (39.81%), Query Frame = 3

Query:  240 CPPVCNQMACNMGILTCSETGLSEIPKLIPPKTNKILLINQDFSEAGTLTRLNLSDYSSXXXXXXXXXXQNCSLQAIESRAFSQIIYLETLDLSFNKLTELEPFTFADLNLKFLRLDGNLNLKLT--------ANSFKELRVDXXXXXXXXXXXXPFTVL-EPISTGLIQL---ILTSNRFTTLESRYETLFQRLSRFGLDDNRFDCSQCSLIWMANTMKAIYYKNQNKDQQTIIYPKCHQPYKLKDKFIHSLSSSDFQCPKPSIEKISIFILPNNTAQLICTASDV-----QSSVIWSQVFEPNDKDFLLIEQ 1130
            CP VC+    N   + CS  GL+ +P+ I     ++ L      +   LT +  +D+             N  +  IE  +F  ++ LE L L+ N+L  + P  F   +   LRLD + N+  T        A S + L++D+             T L E    GL++L    L +N  T+L         RL    L DN F C  C L W++  +++          +   Y +C  P +LK + +  L   +F+C   + E   +     N+    C  +D      + S+    V  P+D   L +EQ
Sbjct:   73 CPRVCSCTGLN---VDCSHRGLTSVPRKISADVERLEL------QGNNLTVIYETDFQRLTKLRMLQLTDN-QIHTIERNSFQDLVSLERLRLNNNRLKAI-PENFVTSSASLLRLDISNNVITTVGRRVFKGAQSLRSLQLDNNQ----------ITCLDEHAFKGLVELEILTLNNNNLTSLPHNIFGGLGRLRALRLSDNPFAC-DCHLSWLSRFLRSA--------TRLAPYTRCQSPSQLKGQNVADLHDQEFKCSGLT-EHAPMECGAENSCPHPCRCADGIVDCREKSLTSVPVTLPDDTTELRLEQ 355

HSP 2 Score: 53.5286 bits (127), Expect = 7.938e-7
Identity = 62/257 (24.12%), Postives = 96/257 (37.35%), Query Frame = 3

Query:  240 CPPVCNQMACNMGILTCSETGLSEIPKLIPPKTNKILLINQDFSEAG--------TLTRLNLSDYSSXXXXXXXXXXQNCSLQAIESRAFSQIIYLETLDLSFNKLTELEPFTFADL-NLKFLRLDGNLNLKLTANSFKELRVDXXXXXXXXXXXXPFTVLEPISTGLIQLILTSNRFTTLESRYETLFQRLSRFGLDDNRFDCSQCSLIWMANTMKAIYYKNQNKDQQTIIYPKCHQPYKLKDKFIHSLSSSDFQC 983
            CPP C    C   ++ CS   L EIP+ IP +T+++ L + +  +          +LTRL+LS               N  +  + +  F+ +  L TL +S+NKL  L+    + L NL+ L L GN    L   SF++L+                                                 L+   L  N   C  C L W ++ +K  Y +            +C +P ++KDK I S  SS F C
Sbjct:  739 CPPSC---TCTGTVVRCSRNQLKEIPRGIPAETSELYLESNEIEQIHYERIRHLRSLTRLDLS---------------NNQITILSNYTFANLTKLSTLIISYNKLQCLQRHALSGLNNLRVLSLHGNRISMLPEGSFEDLK------------------------------------------------SLTHIALGSNPLYC-DCGLKWFSDWIKLDYVEPG--------IARCAEPEQMKDKLILSTPSSSFVC 920

[Close]

BLAST of Ig-like domain-containing protein vs. Ensembl Fly
Match: sli (gene:FBgn0264089 transcript:FBtr0330731)

HSP 1 Score: 60.4622 bits (145), Expect = 6.077e-9
Identity = 76/314 (24.20%), Postives = 125/314 (39.81%), Query Frame = 3

Query:  240 CPPVCNQMACNMGILTCSETGLSEIPKLIPPKTNKILLINQDFSEAGTLTRLNLSDYSSXXXXXXXXXXQNCSLQAIESRAFSQIIYLETLDLSFNKLTELEPFTFADLNLKFLRLDGNLNLKLT--------ANSFKELRVDXXXXXXXXXXXXPFTVL-EPISTGLIQL---ILTSNRFTTLESRYETLFQRLSRFGLDDNRFDCSQCSLIWMANTMKAIYYKNQNKDQQTIIYPKCHQPYKLKDKFIHSLSSSDFQCPKPSIEKISIFILPNNTAQLICTASDV-----QSSVIWSQVFEPNDKDFLLIEQ 1130
            CP VC+    N   + CS  GL+ +P+ I     ++ L      +   LT +  +D+             N  +  IE  +F  ++ LE L L+ N+L  + P  F   +   LRLD + N+  T        A S + L++D+             T L E    GL++L    L +N  T+L         RL    L DN F C  C L W++  +++          +   Y +C  P +LK + +  L   +F+C   + E   +     N+    C  +D      + S+    V  P+D   L +EQ
Sbjct:   73 CPRVCSCTGLN---VDCSHRGLTSVPRKISADVERLEL------QGNNLTVIYETDFQRLTKLRMLQLTDN-QIHTIERNSFQDLVSLERLRLNNNRLKAI-PENFVTSSASLLRLDISNNVITTVGRRVFKGAQSLRSLQLDNNQ----------ITCLDEHAFKGLVELEILTLNNNNLTSLPHNIFGGLGRLRALRLSDNPFAC-DCHLSWLSRFLRSA--------TRLAPYTRCQSPSQLKGQNVADLHDQEFKCSGLT-EHAPMECGAENSCPHPCRCADGIVDCREKSLTSVPVTLPDDTTELRLEQ 355

HSP 2 Score: 53.5286 bits (127), Expect = 7.938e-7
Identity = 62/257 (24.12%), Postives = 96/257 (37.35%), Query Frame = 3

Query:  240 CPPVCNQMACNMGILTCSETGLSEIPKLIPPKTNKILLINQDFSEAG--------TLTRLNLSDYSSXXXXXXXXXXQNCSLQAIESRAFSQIIYLETLDLSFNKLTELEPFTFADL-NLKFLRLDGNLNLKLTANSFKELRVDXXXXXXXXXXXXPFTVLEPISTGLIQLILTSNRFTTLESRYETLFQRLSRFGLDDNRFDCSQCSLIWMANTMKAIYYKNQNKDQQTIIYPKCHQPYKLKDKFIHSLSSSDFQC 983
            CPP C    C   ++ CS   L EIP+ IP +T+++ L + +  +          +LTRL+LS               N  +  + +  F+ +  L TL +S+NKL  L+    + L NL+ L L GN    L   SF++L+                                                 L+   L  N   C  C L W ++ +K  Y +            +C +P ++KDK I S  SS F C
Sbjct:  739 CPPSC---TCTGTVVRCSRNQLKEIPRGIPAETSELYLESNEIEQIHYERIRHLRSLTRLDLS---------------NNQITILSNYTFANLTKLSTLIISYNKLQCLQRHALSGLNNLRVLSLHGNRISMLPEGSFEDLK------------------------------------------------SLTHIALGSNPLYC-DCGLKWFSDWIKLDYVEPG--------IARCAEPEQMKDKLILSTPSSSFVC 920

[Close]

BLAST of Ig-like domain-containing protein vs. Ensembl Fly
Match: sli (gene:FBgn0264089 transcript:FBtr0330730)

HSP 1 Score: 59.3066 bits (142), Expect = 1.226e-8
Identity = 71/306 (23.20%), Postives = 118/306 (38.56%), Query Frame = 3

Query:  240 CPPVCNQMACNMGILTCSETGLSEIPKLIPPKTNKILLINQDFSEAGTLTRLNLSDYSSXXXXXXXXXXQNCSLQAIESRAFSQIIYLETLDLSFNKLTELEPFTFADL-NLKFLRLDGNLNLKLTANSFKELRVDXXXXXXXXXXXXPFTVLEPISTGLIQL---ILTSNRFTTLESRYETLFQRLSRFGLDDNRFDCSQCSLIWMANTMKAIYYKNQNKDQQTIIYPKCHQPYKLKDKFIHSLSSSDFQCPKPSIEKISIFILPNNTAQLICTASDV-----QSSVIWSQVFEPNDKDFLLIEQ 1130
            CP VC+    N   + CS  GL+ +P+ I     ++ L      +   LT +  +D+             N  +  IE  +F  ++ LE LD+S N +T +    F    +L+ L+LD N    L  ++FK                           GL++L    L +N  T+L         RL    L DN F C  C L W++  +++          +   Y +C  P +LK + +  L   +F+C   + E   +     N+    C  +D      + S+    V  P+D   L +EQ
Sbjct:   73 CPRVCSCTGLN---VDCSHRGLTSVPRKISADVERLEL------QGNNLTVIYETDFQRLTKLRMLQLTDN-QIHTIERNSFQDLVSLERLDISNNVITTVGRRVFKGAQSLRSLQLDNNQITCLDEHAFK---------------------------GLVELEILTLNNNNLTSLPHNIFGGLGRLRALRLSDNPFACD-CHLSWLSRFLRSA--------TRLAPYTRCQSPSQLKGQNVADLHDQEFKCSGLT-EHAPMECGAENSCPHPCRCADGIVDCREKSLTSVPVTLPDDTTELRLEQ 331

HSP 2 Score: 53.5286 bits (127), Expect = 7.264e-7
Identity = 62/257 (24.12%), Postives = 96/257 (37.35%), Query Frame = 3

Query:  240 CPPVCNQMACNMGILTCSETGLSEIPKLIPPKTNKILLINQDFSEAG--------TLTRLNLSDYSSXXXXXXXXXXQNCSLQAIESRAFSQIIYLETLDLSFNKLTELEPFTFADL-NLKFLRLDGNLNLKLTANSFKELRVDXXXXXXXXXXXXPFTVLEPISTGLIQLILTSNRFTTLESRYETLFQRLSRFGLDDNRFDCSQCSLIWMANTMKAIYYKNQNKDQQTIIYPKCHQPYKLKDKFIHSLSSSDFQC 983
            CPP C    C   ++ CS   L EIP+ IP +T+++ L + +  +          +LTRL+LS               N  +  + +  F+ +  L TL +S+NKL  L+    + L NL+ L L GN    L   SF++L+                                                 L+   L  N   C  C L W ++ +K  Y +            +C +P ++KDK I S  SS F C
Sbjct:  715 CPPSC---TCTGTVVRCSRNQLKEIPRGIPAETSELYLESNEIEQIHYERIRHLRSLTRLDLS---------------NNQITILSNYTFANLTKLSTLIISYNKLQCLQRHALSGLNNLRVLSLHGNRISMLPEGSFEDLK------------------------------------------------SLTHIALGSNPLYCD-CGLKWFSDWIKLDYVEPG--------IARCAEPEQMKDKLILSTPSSSFVC 896

[Close]

BLAST of Ig-like domain-containing protein vs. Ensembl Fly
Match: sli (gene:FBgn0264089 transcript:FBtr0330729)

HSP 1 Score: 59.3066 bits (142), Expect = 1.292e-8
Identity = 71/306 (23.20%), Postives = 118/306 (38.56%), Query Frame = 3

Query:  240 CPPVCNQMACNMGILTCSETGLSEIPKLIPPKTNKILLINQDFSEAGTLTRLNLSDYSSXXXXXXXXXXQNCSLQAIESRAFSQIIYLETLDLSFNKLTELEPFTFADL-NLKFLRLDGNLNLKLTANSFKELRVDXXXXXXXXXXXXPFTVLEPISTGLIQL---ILTSNRFTTLESRYETLFQRLSRFGLDDNRFDCSQCSLIWMANTMKAIYYKNQNKDQQTIIYPKCHQPYKLKDKFIHSLSSSDFQCPKPSIEKISIFILPNNTAQLICTASDV-----QSSVIWSQVFEPNDKDFLLIEQ 1130
            CP VC+    N   + CS  GL+ +P+ I     ++ L      +   LT +  +D+             N  +  IE  +F  ++ LE LD+S N +T +    F    +L+ L+LD N    L  ++FK                           GL++L    L +N  T+L         RL    L DN F C  C L W++  +++          +   Y +C  P +LK + +  L   +F+C   + E   +     N+    C  +D      + S+    V  P+D   L +EQ
Sbjct:   73 CPRVCSCTGLN---VDCSHRGLTSVPRKISADVERLEL------QGNNLTVIYETDFQRLTKLRMLQLTDN-QIHTIERNSFQDLVSLERLDISNNVITTVGRRVFKGAQSLRSLQLDNNQITCLDEHAFK---------------------------GLVELEILTLNNNNLTSLPHNIFGGLGRLRALRLSDNPFACD-CHLSWLSRFLRSA--------TRLAPYTRCQSPSQLKGQNVADLHDQEFKCSGLT-EHAPMECGAENSCPHPCRCADGIVDCREKSLTSVPVTLPDDTTELRLEQ 331

HSP 2 Score: 53.5286 bits (127), Expect = 7.653e-7
Identity = 62/257 (24.12%), Postives = 96/257 (37.35%), Query Frame = 3

Query:  240 CPPVCNQMACNMGILTCSETGLSEIPKLIPPKTNKILLINQDFSEAG--------TLTRLNLSDYSSXXXXXXXXXXQNCSLQAIESRAFSQIIYLETLDLSFNKLTELEPFTFADL-NLKFLRLDGNLNLKLTANSFKELRVDXXXXXXXXXXXXPFTVLEPISTGLIQLILTSNRFTTLESRYETLFQRLSRFGLDDNRFDCSQCSLIWMANTMKAIYYKNQNKDQQTIIYPKCHQPYKLKDKFIHSLSSSDFQC 983
            CPP C    C   ++ CS   L EIP+ IP +T+++ L + +  +          +LTRL+LS               N  +  + +  F+ +  L TL +S+NKL  L+    + L NL+ L L GN    L   SF++L+                                                 L+   L  N   C  C L W ++ +K  Y +            +C +P ++KDK I S  SS F C
Sbjct:  715 CPPSC---TCTGTVVRCSRNQLKEIPRGIPAETSELYLESNEIEQIHYERIRHLRSLTRLDLS---------------NNQITILSNYTFANLTKLSTLIISYNKLQCLQRHALSGLNNLRVLSLHGNRISMLPEGSFEDLK------------------------------------------------SLTHIALGSNPLYCD-CGLKWFSDWIKLDYVEPG--------IARCAEPEQMKDKLILSTPSSSFVC 896

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BLAST of Ig-like domain-containing protein vs. Ensembl Zebrafish
Match: lrrc4ba (leucine rich repeat containing 4Ba [Source:ZFIN;Acc:ZDB-GENE-080327-25])

HSP 1 Score: 62.7734 bits (151), Expect = 9.643e-10
Identity = 85/398 (21.36%), Postives = 154/398 (38.69%), Query Frame = 3

Query:  453 CSLQAIESRAFSQIIYLETLDLSFNKLTELEPFTFADL-NLKFLRLDGNLNLKLTANSFKELRVDXXXXXXXXXXXXPFTVLEPISTGLIQLILTSNRFTTLESRYETLFQRLSRFGLDDNRFDCSQCSLIWMANTMKAIYYKNQNKDQQTIIYPKCHQPYKLKDKFIHSLSSSDFQCPKPSIEK--ISIFILPNNTAQLICTASDVQSSVIWSQVFEPNDKDFLLIEQRKQILSNSAHSNKLVINKN--QDIDVFLCTVTSLIGNASSTR--------LQISWPKYKTQFRLLNNSHRNVWNDPLTPMPGEKYPKNYFF----------------QPQFS--------------LIEMISGVVGTFIATLIVFITMLRCIFYRIRLFSKNSQLRDHQ 1517
            C L+ I +   + ++ LE L+LS N+L  + P +F  L +L+ L L  +    +  N+F +L+                         L +L L+ N   +L     T  Q+L R  L+ N + C+ C ++W++      ++  +     T    +CH P  LK K+I  L  S F C  P I +    + +     A+L C      +SV W     PN    L+     ++  +  H   L       +D   + C VT+  GN ++T         + +++  + T      +S    +N+    +PG   P  + +                +P F+              +++    ++G F+A   +   ML  +FY++R   K  QL  H 
Sbjct:  207 CGLKDIPN--LTPLVRLEELELSGNRLEIIRPGSFQGLESLRKLWLMHSQMSVIERNAFDDLK------------------------NLEELNLSHNSLHSLPHDLFTPLQKLERVHLNHNPWVCN-CDVLWLS------WWLKETVPSNTTCCARCHAPPYLKGKYIGELDQSHFTCYAPVIVEPPTDLNVTEGMAAELKCRTGTSMTSVNW---ITPNGT--LMTHGSYRVRISVLHDGTLNFTNVTLRDTGQYTCMVTNSAGNTTATAVLNVTAADVSVNYTYFTTVTVETEDSALRTFNETFIHIPGPT-PSGHLWHEVVPTTASSLSIFATKPTFTVPISEPSYPSGLDDVMKTTKIIIGCFVAITFMAAVML-VVFYKLR---KQHQLHKHH 561

[Close]

Query:  453 CSLQAIESRAFSQIIYLETLDLSFNKLTELEPFTFADL-NLKFLRLDGNLNLKLTANSFKELRVDXXXXXXXXXXXXPFTVLEPISTGLIQLILTSNRFTTLESRYETLFQRLSRFGLDDNRFDCSQCSLIWMANTMKAIYYKNQNKDQQTIIYPKCHQPYKLKDKFIHSLSSSDFQCPKPSIEK--ISIFILPNNTAQLICTASDVQSSVIWSQVFEPNDKDFLLIEQRKQILSNSAHSNKLVINKN--QDIDVFLCTVTSLIGNASSTR--------LQISWPKYKTQFRLLNNSHRNVWNDPLTPMPGEKYPKNYFF----------------QPQFS--------------LIEMISGVVGTFIATLIVFITMLRCIFYRIRLFSKNSQLRDHQ 1517
            C L+ I +   + ++ LE L+LS N+L  + P +F  L +L+ L L  +    +  N+F +L+                         L +L L+ N   +L     T  Q+L R  L+ N + C+ C ++W++      ++  +     T    +CH P  LK K+I  L  S F C  P I +    + +     A+L C      +SV W     PN    L+     ++  +  H   L       +D   + C VT+  GN ++T         + +++  + T      +S    +N+    +PG   P  + +                +P F+              +++    ++G F+A   +   ML  +FY++R   K  QL  H 
Sbjct:  207 CGLKDIPN--LTPLVRLEELELSGNRLEIIRPGSFQGLESLRKLWLMHSQMSVIERNAFDDLK------------------------NLEELNLSHNSLHSLPHDLFTPLQKLERVHLNHNPWVCN-CDVLWLS------WWLKETVPSNTTCCARCHAPPYLKGKYIGELDQSHFTCYAPVIVEPPTDLNVTEGMAAELKCRTGTSMTSVNW---ITPNGT--LMTHGSYRVRISVLHDGTLNFTNVTLRDTGQYTCMVTNSAGNTTATAVLNVTAADVSVNYTYFTTVTVETEDSALRTFNETFIHIPGPT-PSGHLWHEVVPTTASSLSIFATKPTFTVPISEPSYPSGLDDVMKTTKIIIGCFVAITFMAAVML-VVFYKLR---KQHQLHKHH 561

[Close]

BLAST of Ig-like domain-containing protein vs. Ensembl Zebrafish
Match: lrrc4ba (leucine rich repeat containing 4Ba [Source:ZFIN;Acc:ZDB-GENE-080327-25])

HSP 1 Score: 61.2326 bits (147), Expect = 3.762e-9
Identity = 67/272 (24.63%), Postives = 112/272 (41.18%), Query Frame = 3

Query:  453 CSLQAIESRAFSQIIYLETLDLSFNKLTELEPFTFADL-NLKFLRLDGNLNLKLTANSFKELRVDXXXXXXXXXXXXPFTVLEPISTGLIQLILTSNRFTTLESRYETLFQRLSRFGLDDNRFDCSQCSLIWMANTMKAIYYKNQNKDQQTIIYPKCHQPYKLKDKFIHSLSSSDFQCPKPSIEK--ISIFILPNNTAQLICTASDVQSSVIWSQVFEPNDKDFLLIEQRKQILSNSAHSNKLVINKN--QDIDVFLCTVTSLIGNASSTRL 1253
            C L+ I +   + ++ LE L+LS N+L  + P +F  L +L+ L L  +    +  N+F +L+                         L +L L+ N   +L     T  Q+L R  L+ N + C+ C ++W++  +K     N      T    +CH P  LK K+I  L  S F C  P I +    + +     A+L C      +SV W     PN    L+     ++  +  H   L       +D   + C VT+  GN ++T +
Sbjct:  200 CGLKDIPN--LTPLVRLEELELSGNRLEIIRPGSFQGLESLRKLWLMHSQMSVIERNAFDDLK------------------------NLEELNLSHNSLHSLPHDLFTPLQKLERVHLNHNPWVCN-CDVLWLSWWLKETVPSN------TTCCARCHAPPYLKGKYIGELDQSHFTCYAPVIVEPPTDLNVTEGMAAELKCRTGTSMTSVNW---ITPNGT--LMTHGSYRVRISVLHDGTLNFTNVTLRDTGQYTCMVTNSAGNTTATAV 433

[Close]

BLAST of Ig-like domain-containing protein vs. Ensembl Zebrafish
Match: lrrc4ba (leucine rich repeat containing 4Ba [Source:ZFIN;Acc:ZDB-GENE-080327-25])

HSP 1 Score: 60.8474 bits (146), Expect = 4.900e-9
Identity = 67/270 (24.81%), Postives = 111/270 (41.11%), Query Frame = 3

Query:  453 CSLQAIESRAFSQIIYLETLDLSFNKLTELEPFTFADL-NLKFLRLDGNLNLKLTANSFKELRVDXXXXXXXXXXXXPFTVLEPISTGLIQLILTSNRFTTLESRYETLFQRLSRFGLDDNRFDCSQCSLIWMANTMKAIYYKNQNKDQQTIIYPKCHQPYKLKDKFIHSLSSSDFQCPKPSIEK--ISIFILPNNTAQLICTASDVQSSVIWSQVFEPNDKDFLLIEQRKQILSNSAHSNKLVINKN--QDIDVFLCTVTSLIGNASST 1247
            C L+ I +   + ++ LE L+LS N+L  + P +F  L +L+ L L  +    +  N+F +L+                         L +L L+ N   +L     T  Q+L R  L+ N + C+ C ++W++  +K     N      T    +CH P  LK K+I  L  S F C  P I +    + +     A+L C      +SV W     PN    L+     ++  +  H   L       +D   + C VT+  GN ++T
Sbjct:  200 CGLKDIPN--LTPLVRLEELELSGNRLEIIRPGSFQGLESLRKLWLMHSQMSVIERNAFDDLK------------------------NLEELNLSHNSLHSLPHDLFTPLQKLERVHLNHNPWVCN-CDVLWLSWWLKETVPSN------TTCCARCHAPPYLKGKYIGELDQSHFTCYAPVIVEPPTDLNVTEGMAAELKCRTGTSMTSVNW---ITPNGT--LMTHGSYRVRISVLHDGTLNFTNVTLRDTGQYTCMVTNSAGNTTAT 431

[Close]

BLAST of Ig-like domain-containing protein vs. Ensembl Zebrafish
Match: lrrc4ba (leucine rich repeat containing 4Ba [Source:ZFIN;Acc:ZDB-GENE-080327-25])

HSP 1 Score: 60.8474 bits (146), Expect = 5.013e-9
Identity = 67/270 (24.81%), Postives = 111/270 (41.11%), Query Frame = 3

Query:  453 CSLQAIESRAFSQIIYLETLDLSFNKLTELEPFTFADL-NLKFLRLDGNLNLKLTANSFKELRVDXXXXXXXXXXXXPFTVLEPISTGLIQLILTSNRFTTLESRYETLFQRLSRFGLDDNRFDCSQCSLIWMANTMKAIYYKNQNKDQQTIIYPKCHQPYKLKDKFIHSLSSSDFQCPKPSIEK--ISIFILPNNTAQLICTASDVQSSVIWSQVFEPNDKDFLLIEQRKQILSNSAHSNKLVINKN--QDIDVFLCTVTSLIGNASST 1247
            C L+ I +   + ++ LE L+LS N+L  + P +F  L +L+ L L  +    +  N+F +L+                         L +L L+ N   +L     T  Q+L R  L+ N + C+ C ++W++  +K     N      T    +CH P  LK K+I  L  S F C  P I +    + +     A+L C      +SV W     PN    L+     ++  +  H   L       +D   + C VT+  GN ++T
Sbjct:  200 CGLKDIPN--LTPLVRLEELELSGNRLEIIRPGSFQGLESLRKLWLMHSQMSVIERNAFDDLK------------------------NLEELNLSHNSLHSLPHDLFTPLQKLERVHLNHNPWVCN-CDVLWLSWWLKETVPSN------TTCCARCHAPPYLKGKYIGELDQSHFTCYAPVIVEPPTDLNVTEGMAAELKCRTGTSMTSVNW---ITPNGT--LMTHGSYRVRISVLHDGTLNFTNVTLRDTGQYTCMVTNSAGNTTAT 431

[Close]

BLAST of Ig-like domain-containing protein vs. Ensembl Xenopus
Match: lrrc4b (leucine rich repeat containing 4B [Source:NCBI gene;Acc:100124949])

HSP 1 Score: 62.3882 bits (150), Expect = 2.245e-9
Identity = 65/270 (24.07%), Postives = 110/270 (40.74%), Query Frame = 3

Query:  453 CSLQAIESRAFSQIIYLETLDLSFNKLTELEPFTFADL-NLKFLRLDGNLNLKLTANSFKELRVDXXXXXXXXXXXXPFTVLEPISTGLIQLILTSNRFTTLESRYETLFQRLSRFGLDDNRFDCSQCSLIWMANTMKAIYYKNQNKDQQTIIYPKCHQPYKLKDKFIHSLSSSDFQCPKPSIEK--ISIFILPNNTAQLICTASDVQSSVIWSQVFEPNDKDFLLIEQRKQILSNSAHSNKLVINK--NQDIDVFLCTVTSLIGNASST 1247
            C+L+ I +   + ++ LE L+LS N+L  + P +F  L +L+ L L       +  N+F +L+                         L +L L+ N   +L     T   RL R  L+ N + C+ C ++W++      ++  +     T    +CH P  LK ++I  L  S F C  P I +    + +     A+L C      +SV W     PN    L+     ++  +  H   L       QD   + C VT+  GN ++T
Sbjct:  202 CNLKDIPN--LTALVRLEELELSGNRLEMIRPGSFQGLTSLRKLWLMHAHVTIIERNAFDDLK------------------------SLEELNLSHNNLMSLPHDLFTPLHRLERVHLNHNPWHCN-CDVLWLS------WWLKETVPNNTTCCARCHSPPNLKMRYIGELDQSHFTCYAPVIVEPPTDLNVTEGMAAELKCRTGTSMTSVNW---LTPNGT--LMTHGSYRVRISVLHDGTLNFTNVTVQDTGQYTCMVTNSAGNTTAT 433

[Close]

BLAST of Ig-like domain-containing protein vs. Ensembl Xenopus
Match: lrrc4 (leucine rich repeat containing 4 [Source:NCBI gene;Acc:100493671])

HSP 1 Score: 57.3806 bits (137), Expect = 7.061e-8
Identity = 95/415 (22.89%), Postives = 157/415 (37.83%), Query Frame = 3

Query:  240 CPPVC---NQMACNMGILTCSETGLSEIPKLIPPKT-------NKILLINQD-------------------------FSEAGTLTRLNL---------SDYSSXXXXXXXXXXQNCSLQAIESRAFSQIIYLETLDLS-FNKLTELEPFTFADL-NLKFLRLD--------------GNLNLKLTANSFKELRVDXXXXXXXXX----XXXPFTVLEPIS----TGLIQLILTSNRFTTLESRYETLFQRLSRFGLDDNRFDCSQCSLIWMANTMKAIYYKNQNKDQQTIIYPKCHQPYKLKDKFIHSLSSSDFQCPKPSIEKI--SIFILPNNTAQLICTASDVQSSVIWSQVFEPNDKDFLLIEQRKQILSNSAHSNKLVINKN---------QDIDVFLCTVTSLIGNASST 1247
            CP VC   NQ +     + C+  GLSE+P+ IP  T       N I +I  D                         F+   +L  L L         S       K+ ++ ++N  +++I S AF+++  L  LDL    KL  +    F  L NLK+L L               G   L+++ N+F E++  S   L         +     +E  +    T L++L L  N  T+L        + L    L  N +DC  C ++W++      ++  +     +    +CH P  ++ K++  +  S FQC  P I      + I     A+L C  S   SSV W            L+     +   S H    ++N            D  V+ C VT++ GN++++
Sbjct:   40 CPSVCSCSNQFS----KVVCTRRGLSEVPQGIPSNTRSLNLMENNIQMIQADTFRHLHHLEVLQLGRNSIRQIEVGAFNGLASLNTLELFDNWLTVIPSGAFEYLSKLRELWLRNNPIESIPSYAFNRVPSLMRLDLGELKKLEYISEGAFEGLYNLKYLNLGMCNIRDMPNLTPLVGLEELEISGNNFPEIKPGSFHGLRSLKKLWIMNSQINTIERNAFDDLTSLVELNLAHNNVTSLPHDLFAPLKYLVELHLHHNPWDC-DCDVLWLS------WWLREYIPTNSTCCGRCHSPPHMRGKYVVEVDHSMFQCSAPFIMDAPRDLNISEGRMAELKCRTS-AMSSVRW------------LLPNGTVLTHASNHPRITILNDGTLNFSQVLLTDTGVYTCMVTNVAGNSNAS 430

[Close]

BLAST of Ig-like domain-containing protein vs. Ensembl Xenopus
Match: LINGO2 (leucine rich repeat and Ig domain containing 2 [Source:NCBI gene;Acc:100490134])

HSP 1 Score: 54.299 bits (129), Expect = 6.720e-7
Identity = 78/304 (25.66%), Postives = 118/304 (38.82%), Query Frame = 3

Query:  363 DFSEAGTLTRLNLSDYSSXXXXXXXXXXQNCSLQAIESRAFSQIIYLETLDLSFNKLTELEPFTFADL-NLKFLRLDGNLNLKLTANSFKELRVDXXXXXXXXXXXXPFTVLEPISTGLIQLILTSNRFTTLESRYETLFQ---RLSRFGLDDNRFDCSQCSLIWMANTMKAIYYKNQNKDQQTIIYPKCHQPYKLKDKFIHSLSSSD----FQCPKPSI---EKISIFILPNNTAQLICTA-SDVQSSVIWSQVFEPNDKDFLLIEQ-RKQILSNSAHSNKLVINKNQDIDVFLCTVTSLIGN 1235
            D   A +L  LNL+  S          I N +L  I   A   +IYL  L+LS+N +  ++   F+DL  L+ L L G     +  ++F+ LR               F  L  +S  L++         TLE   E  FQ    L    +DDN   C  C LIWM      +++  Q         P C  P  LK+     L ++     F C KP I   E + + +      Q+ C A  D Q  + W     P  +   L    R  +L N   + ++   + QD   ++C  ++  GN
Sbjct:  243 DLVPANSLYGLNLTFLS----------ITNTNLSTIPYHALKHLIYLTHLNLSYNPIGIIDTGVFSDLVRLQELHLVGAQLRTIEPHAFQGLR---------------FLRLLNVSQNLLE---------TLE---ENAFQSPKALEVLCIDDNPLVC-DCRLIWMLQRHPMLHFGGQQ--------PMCSSPDSLKESSYKVLDAAVLSFYFTCKKPKIRDREMLQVHVDEGQRVQMNCNADGDPQPMISW---VTPRRRTVSLKSNGRTTVLGNG--TLEIRYAQIQDTGTYICVASNAAGN 495

[Close]

BLAST of Ig-like domain-containing protein vs. Ensembl Xenopus
Match: polr1e (polymerase (RNA) I polypeptide E [Source:Xenbase;Acc:XB-GENE-1003651])

HSP 1 Score: 53.9138 bits (128), Expect = 1.003e-6
Identity = 56/274 (20.44%), Postives = 107/274 (39.05%), Query Frame = 3

Query:  459 LQAIESRAFSQIIYLETLDLSFNKLTELEPFTFADLNLKFLRLDGNLNLKLTANSFKELRVDXXXXXXXXXXXXPFTVLEPISTGLIQLILTSNRFTTLESRYETLFQRLSRFGLDDNRFDCSQCSLIWMANTMKAIYYKNQNKDQQTIIYPKCHQPYKLKDKFIHSLSSSDFQCPKPSI--EKISIFILPNNTAQLICTA-SDVQSSVIWSQVFEPNDKDFLLIEQRKQILSNSAHSNKLVINKNQDID--VFLCTVTSLIGNASSTRLQISW 1265
            +Q+I+ +AF  +  LE L L FN++  LEP +F  L                                                 L +L L +NR T L     +  + + R  LD N   C  C ++W+A+ +K IY ++ N          C  P +L+ + + +++ S+  C +P I  E   + +   NT    C A  + +  +IW +    N+ +  + +  +  L N      L+I   ++ D  ++ C   ++ G   +  + + +
Sbjct:  181 IQSIDRQAFKGLASLEQLYLHFNQIETLEPESFNYL-----------------------------------------------PKLERLFLHNNRITHLVPGTFSQLESMKRLRLDSNALHCD-CEILWLADLLK-IYSESGNAQAAAT----CEYPRRLQGRSVSTITPSELNCERPRITSEPQDVDVTFGNTVYFTCRAEGNPKPEIIWLR----NNNELSMKDDSRLNLLNDG---TLMIQNTKETDQGIYQCMAKNVAGEVKTHEVTLRY 394

[Close]

BLAST of Ig-like domain-containing protein vs. Ensembl Xenopus
Match: polr1e (polymerase (RNA) I polypeptide E [Source:Xenbase;Acc:XB-GENE-1003651])

HSP 1 Score: 53.9138 bits (128), Expect = 1.273e-6
Identity = 56/274 (20.44%), Postives = 108/274 (39.42%), Query Frame = 3

Query:  459 LQAIESRAFSQIIYLETLDLSFNKLTELEPFTFADLNLKFLRLDGNLNLKLTANSFKELRVDXXXXXXXXXXXXPFTVLEPISTGLIQLILTSNRFTTLESRYETLFQRLSRFGLDDNRFDCSQCSLIWMANTMKAIYYKNQNKDQQTIIYPKCHQPYKLKDKFIHSLSSSDFQCPKPSI--EKISIFILPNNTAQLICTA-SDVQSSVIWSQVFEPNDKDFLLIEQRKQILSNSAHSNKLVINKNQDID--VFLCTVTSLIGNASSTRLQISW 1265
            +Q+I+ +AF  +  LE L L FN++  LEP +F  L                                                 L +L L +NR T L     +  + + R  LD N   C  C ++W+A+ +K IY ++ N          C  P +L+ + + +++ S+  C +P I  E   + +   NT    C A  + +  +IW      N++  +  + R  +L++      L+I   ++ D  ++ C   ++ G   +  + + +
Sbjct:  120 IQSIDRQAFKGLASLEQLYLHFNQIETLEPESFNYL-----------------------------------------------PKLERLFLHNNRITHLVPGTFSQLESMKRLRLDSNALHCD-CEILWLADLLK-IYSESGNAQAAAT----CEYPRRLQGRSVSTITPSELNCERPRITSEPQDVDVTFGNTVYFTCRAEGNPKPEIIW---LRNNNELSMKDDSRLNLLNDGT----LMIQNTKETDQGIYQCMAKNVAGEVKTHEVTLRY 333

[Close]

BLAST of Ig-like domain-containing protein vs. Ensembl Mouse
Match: Lrrc4b (leucine rich repeat containing 4B [Source:MGI Symbol;Acc:MGI:3027390])

HSP 1 Score: 63.929 bits (154), Expect = 5.557e-10
Identity = 66/270 (24.44%), Postives = 110/270 (40.74%), Query Frame = 3

Query:  453 CSLQAIESRAFSQIIYLETLDLSFNKLTELEPFTFADL-NLKFLRLDGNLNLKLTANSFKELRVDXXXXXXXXXXXXPFTVLEPISTGLIQLILTSNRFTTLESRYETLFQRLSRFGLDDNRFDCSQCSLIWMANTMKAIYYKNQNKDQQTIIYPKCHQPYKLKDKFIHSLSSSDFQCPKPSIEK--ISIFILPNNTAQLICTASDVQSSVIWSQVFEPNDKDFLLIEQRKQILSNSAHSNKLVINK--NQDIDVFLCTVTSLIGNASST 1247
            C+L+ I +   + ++ LE L+LS N+L  + P +F  L +L+ L L       +  N+F +L+                         L +L L+ N   +L     T   RL R  L+ N + C+ C ++W++  +K     N      T    +CH P  LK ++I  L  S F C  P I +    + +     A+L C      +SV W     PN    L+     ++  +  H   L       QD   + C VT+  GN +++
Sbjct:  219 CNLKDIPN--LTALVRLEELELSGNRLDLIRPGSFQGLTSLRKLWLMHAQVATIERNAFDDLK------------------------SLEELNLSHNNLMSLPHDLFTPLHRLERVHLNHNPWHCN-CDVLWLSWWLKETVPSN------TTCCARCHAPAGLKGRYIGELDQSHFTCYAPVIVEPPTDLNVTEGMAAELKCRTGTSMTSVNW---LTPNGT--LMTHGSYRVRISVLHDGTLNFTNVTVQDTGQYTCMVTNSAGNTTAS 450

[Close]

BLAST of Ig-like domain-containing protein vs. Ensembl Mouse
Match: Slit1 (slit guidance ligand 1 [Source:MGI Symbol;Acc:MGI:1315203])

HSP 1 Score: 60.8474 bits (146), Expect = 2.613e-9
Identity = 64/250 (25.60%), Postives = 100/250 (40.00%), Query Frame = 3

Query:  240 CPPVCNQMACNMGILTCSETGLSEIPKLIPPKTNKILLINQDFSEAGTLTRLNLSDYSSXXXXXXXXXXQNCSLQAIESRAFSQIIYLETLDLSFNKLTELEPFTF-ADLNLKFLRLDGNLNLKLTANSFKELRVDXXXXXXXXXXXXPFTVLEPISTGLIQLILTSNRFTTLESRYETLFQRLSRFGLDDNRFDCSQCSLIWMANTMKAIYYKNQNKDQQTI-IYPKCHQPYKLKDKFIHSLSSSDFQC 983
            CP +C    C    + C  TGL  IPK IP  T ++ L          +TR++ +D++  K       ++N  + A+E  AF  +  LE LDLS N L  +    F    +LK L+LD N    +   +F+ LR                        GL  L L +N  TT+         +L  F L  N   C  C L W++  +         + + TI ++ +C  P  L+   +  +   +F C
Sbjct:   34 CPALC---TCTGTTVDCHGTGLQAIPKNIPRNTERLEL------NGNNITRIHKNDFAGLKQLRVLQLMEN-QIGAVERGAFDDMKELERLDLSENFLQAVPRKAFRGATDLKNLQLDKNRISCIEEGAFRALR------------------------GLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHLFC-DCHLAWLSQWL---------RQRPTIGLFTQCSGPASLRGLNVAEVQKGEFSC 239

[Close]

BLAST of Ig-like domain-containing protein vs. Ensembl Mouse
Match: Lrrc4c (leucine rich repeat containing 4C [Source:MGI Symbol;Acc:MGI:2442636])

HSP 1 Score: 57.3806 bits (137), Expect = 6.131e-8
Identity = 61/268 (22.76%), Postives = 110/268 (41.04%), Query Frame = 3

Query:  453 CSLQAIESRAFSQIIYLETLDLSFNKLTELEPFTFADL-NLKFLRLDGNLNLKLTANSFKELRVDXXXXXXXXXXXXPFTVLEPISTGLIQLILTSNRFTTLESRYETLFQRLSRFGLDDNRFDCSQCSLIWMANTMKAIYYKNQNKDQQTIIYPKCHQPYKLKDKFIHSLSSSDFQCPKPSIEK--ISIFILPNNTAQLICTASDVQSSVIWSQVFEPNDKDFLLIEQRKQILSNSAHSNKLVINKNQDIDVFLCTVTSLIGNASST 1247
            C+L+ I +   + +I L+ LDLS N L+ + P +F  L +L+ L +  +    +  N+F  L+                         L+++ L  N  T L     T    L R  L  N ++C+ C ++W++      ++        T    +C+ P  LK ++I  L  + F C  P I +    + +     A+L C AS   +SV W     PN         + +I   S  +        QD  ++ C V++ +GN +++
Sbjct:  207 CNLREIPN--LTPLIKLDELDLSGNHLSAIRPGSFQGLMHLQKLWMIQSQIQVIERNAFDNLQ------------------------SLVEINLAHNNLTLLPHDLFTPLHHLERIHLHHNPWNCN-CDILWLS------WWIRDMAPSNTACCARCNTPPNLKGRYIGELDQNYFTCYAPVIVEPPADLNVTEGMAAELKCRASTSLTSVSW---ITPNGTVMTHGAYKVRIAVLSDGTLNFTNVTVQDTGMYTCMVSNSVGNTTAS 438

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Query:  453 CSLQAIESRAFSQIIYLETLDLSFNKLTELEPFTFADL-NLKFLRLDGNLNLKLTANSFKELRVDXXXXXXXXXXXXPFTVLEPISTGLIQLILTSNRFTTLESRYETLFQRLSRFGLDDNRFDCSQCSLIWMANTMKAIYYKNQNKDQQTIIYPKCHQPYKLKDKFIHSLSSSDFQCPKPSIEK--ISIFILPNNTAQLICTASDVQSSVIWSQVFEPNDKDFLLIEQRKQILSNSAHSNKLVINKNQDIDVFLCTVTSLIGNASST 1247
            C+L+ I +   + +I L+ LDLS N L+ + P +F  L +L+ L +  +    +  N+F  L+                         L+++ L  N  T L     T    L R  L  N ++C+ C ++W++      ++        T    +C+ P  LK ++I  L  + F C  P I +    + +     A+L C AS   +SV W     PN         + +I   S  +        QD  ++ C V++ +GN +++
Sbjct:  207 CNLREIPN--LTPLIKLDELDLSGNHLSAIRPGSFQGLMHLQKLWMIQSQIQVIERNAFDNLQ------------------------SLVEINLAHNNLTLLPHDLFTPLHHLERIHLHHNPWNCN-CDILWLS------WWIRDMAPSNTACCARCNTPPNLKGRYIGELDQNYFTCYAPVIVEPPADLNVTEGMAAELKCRASTSLTSVSW---ITPNGTVMTHGAYKVRIAVLSDGTLNFTNVTVQDTGMYTCMVSNSVGNTTAS 438

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Query:  453 CSLQAIESRAFSQIIYLETLDLSFNKLTELEPFTFADL-NLKFLRLDGNLNLKLTANSFKELRVDXXXXXXXXXXXXPFTVLEPISTGLIQLILTSNRFTTLESRYETLFQRLSRFGLDDNRFDCSQCSLIWMANTMKAIYYKNQNKDQQTIIYPKCHQPYKLKDKFIHSLSSSDFQCPKPSIEK--ISIFILPNNTAQLICTASDVQSSVIWSQVFEPNDKDFLLIEQRKQILSNSAHSNKLVINKNQDIDVFLCTVTSLIGNASST 1247
            C+L+ I +   + +I L+ LDLS N L+ + P +F  L +L+ L +  +    +  N+F  L+                         L+++ L  N  T L     T    L R  L  N ++C+ C ++W++      ++        T    +C+ P  LK ++I  L  + F C  P I +    + +     A+L C AS   +SV W     PN         + +I   S  +        QD  ++ C V++ +GN +++
Sbjct:  207 CNLREIPN--LTPLIKLDELDLSGNHLSAIRPGSFQGLMHLQKLWMIQSQIQVIERNAFDNLQ------------------------SLVEINLAHNNLTLLPHDLFTPLHHLERIHLHHNPWNCN-CDILWLS------WWIRDMAPSNTACCARCNTPPNLKGRYIGELDQNYFTCYAPVIVEPPADLNVTEGMAAELKCRASTSLTSVSW---ITPNGTVMTHGAYKVRIAVLSDGTLNFTNVTVQDTGMYTCMVSNSVGNTTAS 438

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BLAST of Ig-like domain-containing protein vs. UniProt/SwissProt
Match: sp|P0C192|LRC4B_MOUSE (Leucine-rich repeat-containing protein 4B OS=Mus musculus OX=10090 GN=Lrrc4b PE=1 SV=1)

HSP 1 Score: 63.929 bits (154), Expect = 3.887e-9
Identity = 66/270 (24.44%), Postives = 110/270 (40.74%), Query Frame = 3

Query:  453 CSLQAIESRAFSQIIYLETLDLSFNKLTELEPFTFADL-NLKFLRLDGNLNLKLTANSFKELRVDXXXXXXXXXXXXPFTVLEPISTGLIQLILTSNRFTTLESRYETLFQRLSRFGLDDNRFDCSQCSLIWMANTMKAIYYKNQNKDQQTIIYPKCHQPYKLKDKFIHSLSSSDFQCPKPSIEK--ISIFILPNNTAQLICTASDVQSSVIWSQVFEPNDKDFLLIEQRKQILSNSAHSNKLVINK--NQDIDVFLCTVTSLIGNASST 1247
            C+L+ I +   + ++ LE L+LS N+L  + P +F  L +L+ L L       +  N+F +L+                         L +L L+ N   +L     T   RL R  L+ N + C+ C ++W++  +K     N      T    +CH P  LK ++I  L  S F C  P I +    + +     A+L C      +SV W     PN    L+     ++  +  H   L       QD   + C VT+  GN +++
Sbjct:  219 CNLKDIPN--LTALVRLEELELSGNRLDLIRPGSFQGLTSLRKLWLMHAQVATIERNAFDDLK------------------------SLEELNLSHNNLMSLPHDLFTPLHRLERVHLNHNPWHCN-CDVLWLSWWLKETVPSN------TTCCARCHAPAGLKGRYIGELDQSHFTCYAPVIVEPPTDLNVTEGMAAELKCRTGTSMTSVNW---LTPNGT--LMTHGSYRVRISVLHDGTLNFTNVTVQDTGQYTCMVTNSAGNTTAS 450

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BLAST of Ig-like domain-containing protein vs. UniProt/SwissProt
Match: sp|Q9NT99|LRC4B_HUMAN (Leucine-rich repeat-containing protein 4B OS=Homo sapiens OX=9606 GN=LRRC4B PE=2 SV=3)

HSP 1 Score: 63.929 bits (154), Expect = 3.899e-9
Identity = 64/270 (23.70%), Postives = 110/270 (40.74%), Query Frame = 3

Query:  453 CSLQAIESRAFSQIIYLETLDLSFNKLTELEPFTFADL-NLKFLRLDGNLNLKLTANSFKELRVDXXXXXXXXXXXXPFTVLEPISTGLIQLILTSNRFTTLESRYETLFQRLSRFGLDDNRFDCSQCSLIWMANTMKAIYYKNQNKDQQTIIYPKCHQPYKLKDKFIHSLSSSDFQCPKPSIEK--ISIFILPNNTAQLICTASDVQSSVIWSQVFEPNDKDFLLIEQRKQILSNSAHSNKLVINK--NQDIDVFLCTVTSLIGNASST 1247
            C+L+ I +   + ++ LE L+LS N+L  + P +F  L +L+ L L       +  N+F +L+                         L +L L+ N   +L     T   RL R  L+ N + C+ C ++W++      ++  +     T    +CH P  LK ++I  L  S F C  P I +    + +     A+L C      +SV W     PN    L+     ++  +  H   L       QD   + C VT+  GN +++
Sbjct:  217 CNLKDIPN--LTALVRLEELELSGNRLDLIRPGSFQGLTSLRKLWLMHAQVATIERNAFDDLK------------------------SLEELNLSHNNLMSLPHDLFTPLHRLERVHLNHNPWHCN-CDVLWLS------WWLKETVPSNTTCCARCHAPAGLKGRYIGELDQSHFTCYAPVIVEPPTDLNVTEGMAAELKCRTGTSMTSVNW---LTPNGT--LMTHGSYRVRISVLHDGTLNFTNVTVQDTGQYTCMVTNSAGNTTAS 448

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BLAST of Ig-like domain-containing protein vs. UniProt/SwissProt
Match: sp|P0CC10|LRC4B_RAT (Leucine-rich repeat-containing protein 4B OS=Rattus norvegicus OX=10116 GN=Lrrc4b PE=1 SV=1)

HSP 1 Score: 63.929 bits (154), Expect = 4.093e-9
Identity = 66/270 (24.44%), Postives = 110/270 (40.74%), Query Frame = 3

Query:  453 CSLQAIESRAFSQIIYLETLDLSFNKLTELEPFTFADL-NLKFLRLDGNLNLKLTANSFKELRVDXXXXXXXXXXXXPFTVLEPISTGLIQLILTSNRFTTLESRYETLFQRLSRFGLDDNRFDCSQCSLIWMANTMKAIYYKNQNKDQQTIIYPKCHQPYKLKDKFIHSLSSSDFQCPKPSIEK--ISIFILPNNTAQLICTASDVQSSVIWSQVFEPNDKDFLLIEQRKQILSNSAHSNKLVINK--NQDIDVFLCTVTSLIGNASST 1247
            C+L+ I +   + ++ LE L+LS N+L  + P +F  L +L+ L L       +  N+F +L+                         L +L L+ N   +L     T   RL R  L+ N + C+ C ++W++  +K     N      T    +CH P  LK ++I  L  S F C  P I +    + +     A+L C      +SV W     PN    L+     ++  +  H   L       QD   + C VT+  GN +++
Sbjct:  219 CNLKDIPN--LTALVRLEELELSGNRLDLIRPGSFQGLTSLRKLWLMHAQVATIERNAFDDLK------------------------SLEELNLSHNNLMSLPHDLFTPLHRLERVHLNHNPWHCN-CDVLWLSWWLKETVPSN------TTCCARCHAPAGLKGRYIGELDQSHFTCYAPVIVEPPTDLNVTEGMAAELKCRTGTSMTSVNW---LTPNGT--LMTHGSYRVRISVLHDGTLNFTNVTVQDTGQYTCMVTNSAGNTTAS 450

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BLAST of Ig-like domain-containing protein vs. UniProt/SwissProt
Match: sp|P24014|SLIT_DROME (Protein slit OS=Drosophila melanogaster OX=7227 GN=sli PE=1 SV=2)

HSP 1 Score: 60.4622 bits (145), Expect = 6.091e-8
Identity = 76/314 (24.20%), Postives = 125/314 (39.81%), Query Frame = 3

Query:  240 CPPVCNQMACNMGILTCSETGLSEIPKLIPPKTNKILLINQDFSEAGTLTRLNLSDYSSXXXXXXXXXXQNCSLQAIESRAFSQIIYLETLDLSFNKLTELEPFTFADLNLKFLRLDGNLNLKLT--------ANSFKELRVDXXXXXXXXXXXXPFTVL-EPISTGLIQL---ILTSNRFTTLESRYETLFQRLSRFGLDDNRFDCSQCSLIWMANTMKAIYYKNQNKDQQTIIYPKCHQPYKLKDKFIHSLSSSDFQCPKPSIEKISIFILPNNTAQLICTASDV-----QSSVIWSQVFEPNDKDFLLIEQ 1130
            CP VC+    N   + CS  GL+ +P+ I     ++ L      +   LT +  +D+             N  +  IE  +F  ++ LE L L+ N+L  + P  F   +   LRLD + N+  T        A S + L++D+             T L E    GL++L    L +N  T+L         RL    L DN F C  C L W++  +++          +   Y +C  P +LK + +  L   +F+C   + E   +     N+    C  +D      + S+    V  P+D   L +EQ
Sbjct:   73 CPRVCSCTGLN---VDCSHRGLTSVPRKISADVERLEL------QGNNLTVIYETDFQRLTKLRMLQLTDN-QIHTIERNSFQDLVSLERLRLNNNRLKAI-PENFVTSSASLLRLDISNNVITTVGRRVFKGAQSLRSLQLDNNQ----------ITCLDEHAFKGLVELEILTLNNNNLTSLPHNIFGGLGRLRALRLSDNPFAC-DCHLSWLSRFLRSA--------TRLAPYTRCQSPSQLKGQNVADLHDQEFKCSGLT-EHAPMECGAENSCPHPCRCADGIVDCREKSLTSVPVTLPDDTTELRLEQ 355

HSP 2 Score: 53.5286 bits (127), Expect = 7.957e-6
Identity = 62/257 (24.12%), Postives = 96/257 (37.35%), Query Frame = 3

Query:  240 CPPVCNQMACNMGILTCSETGLSEIPKLIPPKTNKILLINQDFSEAG--------TLTRLNLSDYSSXXXXXXXXXXQNCSLQAIESRAFSQIIYLETLDLSFNKLTELEPFTFADL-NLKFLRLDGNLNLKLTANSFKELRVDXXXXXXXXXXXXPFTVLEPISTGLIQLILTSNRFTTLESRYETLFQRLSRFGLDDNRFDCSQCSLIWMANTMKAIYYKNQNKDQQTIIYPKCHQPYKLKDKFIHSLSSSDFQC 983
            CPP C    C   ++ CS   L EIP+ IP +T+++ L + +  +          +LTRL+LS               N  +  + +  F+ +  L TL +S+NKL  L+    + L NL+ L L GN    L   SF++L+                                                 L+   L  N   C  C L W ++ +K  Y +            +C +P ++KDK I S  SS F C
Sbjct:  739 CPPSC---TCTGTVVRCSRNQLKEIPRGIPAETSELYLESNEIEQIHYERIRHLRSLTRLDLS---------------NNQITILSNYTFANLTKLSTLIISYNKLQCLQRHALSGLNNLRVLSLHGNRISMLPEGSFEDLK------------------------------------------------SLTHIALGSNPLYC-DCGLKWFSDWIKLDYVEPG--------IARCAEPEQMKDKLILSTPSSSFVC 920

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BLAST of Ig-like domain-containing protein vs. UniProt/SwissProt
Match: sp|Q9HCJ2|LRC4C_HUMAN (Leucine-rich repeat-containing protein 4C OS=Homo sapiens OX=9606 GN=LRRC4C PE=1 SV=1)

HSP 1 Score: 58.151 bits (139), Expect = 2.310e-7
Identity = 63/268 (23.51%), Postives = 112/268 (41.79%), Query Frame = 3

Query:  453 CSLQAIESRAFSQIIYLETLDLSFNKLTELEPFTFADL-NLKFLRLDGNLNLKLTANSFKELRVDXXXXXXXXXXXXPFTVLEPISTGLIQLILTSNRFTTLESRYETLFQRLSRFGLDDNRFDCSQCSLIWMANTMKAIYYKNQNKDQQTIIYPKCHQPYKLKDKFIHSLSSSDFQCPKPSIEK--ISIFILPNNTAQLICTASDVQSSVIWSQVFEPNDKDFLLIEQRKQILSNSAHSNKLVINKNQDIDVFLCTVTSLIGNASST 1247
            C+L+ I +   + +I L+ LDLS N L+ + P +F  L +L+ L +  +    +  N+F  L+                         L+++ L  N  T L     T    L R  L  N ++C+ C ++W++  +K +   N      T    +C+ P  LK ++I  L  + F C  P I +    + +     A+L C AS   +SV W     PN         + +I   S  +        QD  ++ C V++ +GN +++
Sbjct:  207 CNLREIPN--LTPLIKLDELDLSGNHLSAIRPGSFQGLMHLQKLWMIQSQIQVIERNAFDNLQ------------------------SLVEINLAHNNLTLLPHDLFTPLHHLERIHLHHNPWNCN-CDILWLSWWIKDMAPSN------TACCARCNTPPNLKGRYIGELDQNYFTCYAPVIVEPPADLNVTEGMAAELKCRASTSLTSVSW---ITPNGTVMTHGAYKVRIAVLSDGTLNFTNVTVQDTGMYTCMVSNSVGNTTAS 438

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BLAST of Ig-like domain-containing protein vs. TrEMBL
Match: A0A5P8I4L0 (PXDN-like protein OS=Schmidtea mediterranea OX=79327 PE=2 SV=1)

HSP 1 Score: 213.772 bits (543), Expect = 1.751e-57
Identity = 158/475 (33.26%), Postives = 251/475 (52.84%), Query Frame = 3

Query:  240 CPPVCNQMACNMGILTCSETGLSEIPKLIPPKTNKILLINQDFSEAGTLTRLNLSDYSSXXXXXXXXXXQNCSLQAIESRAFSQIIYLETLDLSFNKLTELEPFTFADLNLKFLRLDGNLNLKLTANSFKELRVDXXXXXXXXXXXXPFTVLEPISTGLIQLILTSNRFTTLESRYETLFQRLSRFGLDDNRFDCSQCSLIWMANTM----KAIYYKNQNKDQQTIIYPKCHQPYKLKDKFIHSLSSSDFQCPKPSIEKISIFILPNNTAQLICTASDVQSS---VIWSQVFEPNDKDFLLIEQRKQILSN--SAHSNKLVINKNQDIDVFLCTVTSLIGNASSTRLQISWPKYKTQFRLLNNSHRNV------WNDPLTPMPGEK---YPKNYFFQPQFSLIEMISGVVGTFIATLIVFITMLRCIFYRIRLFSKNSQLRDHQLSLTSSKKDKRKQYMTYEPPVYSDSQTYDIP 1610
            CP VC++MAC  G+L C++ GL +IP ++  KT+KI++ NQ FS +  LT  N S+Y    +KI KI +Q C L +I S  FS +  L  LDLS N L E+ P TF  L+L+FLRLD N  ++    SF+ L V  LSL  C+L+ L F V   IS  L +LILT+N+   ++ R+  LF+ L    +++N F+C+ C+L W+ + +    KAI   N +  ++     +C+ P ++K K I  L   DF C  P ++ I +F+   ++A+L C +     S   VIW            + E +   +    S     L + +   ID + C + +   +  +  + I WP      + +NN+ +++       ND +  +P      + ++ F++ QF+L+EMI GVVGTF  T+I+F+ + R                   L++T  + DK+K Y++YE  + SDSQTYDIP
Sbjct:   26 CPSVCHEMACQTGVLACTDGGLLQIPPVLHQKTHKIIVSNQRFS-SPHLTYSNFSNYGPPNYKIEKIALQFCELVSIASNCFSHLTDLRVLDLSHNLLGEIPPDTFKALHLQFLRLDDNKMIQFHRFSFRGLNVAELSLFDCNLTELDFEVFSEISERLKKLILTNNKLNVIDKRFRILFENLPDLQINENPFNCT-CNLRWLNSVLVSRKKAI---NLSSSKRIPNQAQCNYPDRVKGKQIADLDLKDFDCDSPRLKLIDVFMTSTSSAKLTCISEPKAHSSPDVIW------------MTEHKNTYVPEIQSIEKASLSVLRKSRIDKYKCVIKN-NNDYVTVVISIHWP-----VKRVNNASQSLNTLGVSPNDMIPYLPNANSTLHVRSVFYEKQFTLLEMIGGVVGTFTITMILFLCIYR------------------HLAMTMKRNDKKKWYLSYETAIGSDSQTYDIP 459

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BLAST of Ig-like domain-containing protein vs. TrEMBL
Match: I1ZIL5 (Slit-2 OS=Schmidtea mediterranea OX=79327 PE=2 SV=1)

HSP 1 Score: 212.231 bits (539), Expect = 9.933e-57
Identity = 169/494 (34.21%), Postives = 257/494 (52.02%), Query Frame = 3

Query:  240 CPPVCNQMACNMGILTCSETGLSEIPKLIPPKTNKILLINQDFSEAGTLTRLNLSDYSSXXXXXXXXXXQNCSLQAIESRAFSQIIYLETLDLSFNKLTELEPFTFADLNLKFLRLDGNLNLKLTANSFKELRVDXXXXXXXXXXXXPFTVLEPISTGLIQLILTSNRFTTLESRYETLFQRLSRFGLDDNRFDCSQCSLIWMANTMKAIYYKNQNKDQQTIIY---PKCHQPYKLKDKFIHSLSSSDFQCPKPSIEKISIFILPNNTAQLICTASDVQSS-VIWSQVFEPNDKDFLLIEQRKQILSNSAHSNKLVINKNQDIDVFLCTVTSLIGNASSTRLQISWPKYKTQF---------RLLN--NSHRNVWNDPLTPMPGEKYPKNYFFQPQFSLIEMISGVVGTFIATLIVFITMLRCIFYRIRLFSKNSQLRDHQLSLTSSKKDKRKQYMTYEPPVYSDSQTYDIPTL-PVNQSTLGHFIDFKTQQTL 1673
            CP +CNQ AC + +L C   GL +IP   P    K++L NQ+F     LT  NLS Y S++  + K+TI NCSL +IES AFS +IYL+ LDLS N+L  + P TF  L+LK L LD N NL+L  +SF+ L V SLS+  CHL  L    ++ IS  L  L L  NR   L + ++ LF+ L    L++N F+CS C L W+A T++    +  N  + +++    P C  P  LK   I +LS   FQC  P +++I I +    TA++ C + D+ +S V W   +  +   +   +Q     ++  +   ++++K  + D + C + +  GNA +  ++I WP    ++           +N  N   N+    +     +K   NY +  Q++ IEM+  + GTFI TL+ FI +   I YR     KNS+               +     YE  VYS+SQTYD+P + P ++S  G  +DFKTQQ +
Sbjct:   35 CPELCNQGACKLTMLLCETPGLLQIPMNPPRGIQKVILSNQNFLYP-RLTYTNLSRYGSEEIILKKLTISNCSLTSIESEAFSHLIYLQELDLSSNRLLFIYPNTFKSLSLKTLVLDSNRNLQLAKDSFRGLVVQSLSMKDCHLKILTHESIKQISGYLTTLNLADNRLEYLSNDFDLLFRGLDNLNLENNLFNCS-CQLKWLALTLQTRTKRRDNSPKHSLLRLTNPVCEYPKNLKGSSIENLSIVSFQCQIPKLQRIDIKVTSEITAEISCISDDMSNSQVKWRYRYNLSPLFYRYPDQ-----NSGVNQASIIVSKKSEFDFYSCLIINENGNA-TVDIKIKWPTLNKEYVESPINSPPNTVNQFNLRNNITKSSVILKEFDKLHVNYLWIKQYTFIEMVLAICGTFIITLVTFILLYVVINYR----RKNSR--------------SKNILKGYEVGVYSESQTYDVPQMSPYHESNTGRLLDFKTQQEI 502

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BLAST of Ig-like domain-containing protein vs. TrEMBL
Match: A0A0R3TNY6 (Ig-like domain-containing protein OS=Rodentolepis nana OX=102285 GN=HNAJ_LOCUS9134 PE=4 SV=1)

HSP 1 Score: 144.436 bits (363), Expect = 3.681e-32
Identity = 138/462 (29.87%), Postives = 222/462 (48.05%), Query Frame = 3

Query:  249 VCNQMACNMGILTCSETG-LSEIPKLIPPKTNKILLINQDFSEAGTLTRLNLSDYSSXXXXXXXXXXQNCSLQAIESRAFSQIIYLETLDLSFNKLTELEPFTFADLNLKFLRLDGNLNLKLTANSFKELRVDXXXXXXXXXXXXPFTVLEPI--STGLIQLILTSNRFTTLESRYETLFQRLSRFGLDDNRFDCSQCSLIWMANTMKAIYYKNQNKDQQTII------------YPKCHQPYKLKDKFIHSLSSSDFQCPKPSIEKISI----FILP-----NNTAQLICTASDVQSSVIWSQVFEPNDKDFLLIEQRKQILSNSAHSNKLVI---------------NKNQDIDVFLCTVTSLIGNASSTRLQISWPKYKTQFRLLNNSHRNVWNDPLTPMPGEKYPK------------NYFFQPQFSLIEMISGVVGTFIATLIVFITMLRCIFYRIR 1481
            +C+   C  G ++C E G L  +P  +PP   K+++++Q F ++  L+R N+S YS     I ++TI +C L+AIESR FS +  L  LD+S N L+ ++  TF+ L L  LRLD N  L L A +F+ L V SLS+  C L  L F V  P+  S  L  L LTSN  TTL+ R+E  F+ LS   L  N F C  C L+W++ T++    +  N D   +I            +P C  P +L+ K I +L+S+DF C  P ++ + +    F +      N TA ++   +   S  +    F+ +     L+      LS S H +  V+                  +  ++F C      GN S+  L + WP ++    ++ +   +  N P+ P     Y +             +FF  +F+++E+I  VVGTF AT+++F+     ++ R R
Sbjct:   34 ICD--GCIYGSISCQEAGRLHMLPNDLPPGIRKVIIVSQRF-DSQFLSRQNISSYSLPGTVIQELTIMDCGLRAIESRTFSGLNSLTKLDVSKNSLSRIQGNTFSGLRLDLLRLDDNQGLTLDAEAFENLTVSSLSMQNCGLRSLSFEVFRPLLQSGTLTTLRLTSNSLTTLDIRFEPFFRNLSFLSLAKNPFTC-DCKLMWLSRTLQR-KRREDNDDAFPMINDDILLIEPDDDHPICESPSRLRGKQIVTLASTDFYCGPPQMKALEVDFSSFRVGGGETVNTTAGIVIKCAAQGSPEMQLAWFQRDRWGNGLVP-----LSGSKHVSPGVVEVSISRSLLAKNSTGGSEELGELFTCMGIDTYGNTSAD-LSLRWPAFQPT-SIVPSQPSDKRNSPVPPAGDADYLEVDQKSFKTDRLDEFFFMKKFTVLELIGAVVGTFTATIMLFLMGYILLYMRHR 483

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BLAST of Ig-like domain-containing protein vs. TrEMBL
Match: W6U6F3 (Immunoglobulin superfamily member OS=Echinococcus granulosus OX=6210 GN=EGR_08348 PE=4 SV=1)

HSP 1 Score: 140.969 bits (354), Expect = 5.024e-31
Identity = 136/452 (30.09%), Postives = 217/452 (48.01%), Query Frame = 3

Query:  264 ACNMGILTCSETGLSE-IPKLIPPKTNKILLINQDFSEAGTLTRLNLSDYSSXXXXXXXXXXQNCSLQAIESRAFSQIIYLETLDLSFNKLTELEPFTFADLNLKFLRLDGNLNLKLTANSFKELRVDXXXXXXXXXXXXPFTVLEPI--STGLIQLILTSNRFTTLESRYETLFQRLSRFGLDDNRFDCSQCSLIWMANTMKAI-------YYKNQNKDQQTII----YPKCHQPYKLKDKFIHSLSSSDFQCPKPSIEKISIFILPNNTAQ-----------LICTA-SDVQSSVIWSQVFEPNDKDFLLIEQRK---QILSNSAHSNKLVINKNQDID----VFLCTVTSLIGNASSTRLQISWPKYKTQFRLLNNSHRNVWNDPLTPMPGE-KYPKN------------YFFQPQFSLIEMISGVVGTFIATLIVFITMLRCIFYRIR 1481
             C  G ++C E  L   +P  +P    K+++++Q F ++  L+R N+S Y+     I ++TI +C L+AIE+  FS +  L  LDLS N L+ ++  TF+ L L  LRLD N  L L + +F+ L V SLS+  C L  L + V +P+  S  L  L LTSN  TTL++R+E  F+ LS   L  N F C  C L+W++ T++          ++  N D+  I+    +P C  P +L+ K I SLS+ DF C  P +  + +        Q           + C A    +  + W +     D+   L   R+    ++  S   + L  N N + +    +F C      GN S+  L + WP       L ++   N  N P+ P  G+ KY  N            +FF  +F+++E+I  VVGTF AT+++F+     ++ R R
Sbjct:   37 GCTYGSISCQEADLLHMLPNDLPNGIEKVIIVSQRF-DSQFLSRQNISSYTLPGVNIHELTIMHCGLRAIEAGTFSGLSSLTKLDLSKNSLSRIQGHTFSGLRLDLLRLDDNQGLTLDSEAFENLTVSSLSMQNCGLRSLSYEVFQPLVQSRSLTTLRLTSNSLTTLDARFEPFFRNLSFLSLARNPFVC-DCKLVWLSQTLQRKRRADSDDAFRRLNDDRLLIVPDDDHPVCESPNRLRGKQIVSLSTRDFFCGPPQMRTLEVDFSDLRVGQSETFNMTGVVLIKCAAQGSPEMQLAWFRRDGRGDEPIRLPGLRQVASGVVEVSISHSLLAKNSNSETEDAGQLFTCLGVDTYGNTSAD-LSLRWPALPLLSPLPSSPTSNNRN-PMEPSSGDSKYLNNDKGYFQSDHLDEFFFMKKFTILELIGAVVGTFTATILLFLMGYILLYMRHR 484

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BLAST of Ig-like domain-containing protein vs. TrEMBL
Match: A0A068YC11 (Variable lymphocyte receptor OS=Echinococcus multilocularis OX=6211 GN=EmuJ_000739800 PE=4 SV=1)

HSP 1 Score: 137.502 bits (345), Expect = 7.821e-30
Identity = 136/453 (30.02%), Postives = 218/453 (48.12%), Query Frame = 3

Query:  264 ACNMGILTCSETGLSE-IPKLIPPKTNKILLINQDFSEAGTLTRLNLSDYSSXXXXXXXXXXQNCSLQAIESRAFSQIIYLETLDLSFNKLTELEPFTFADLNLKFLRLDGNLNLKLTANSFKELRVDXXXXXXXXXXXXPFTVLEPI--STGLIQLILTSNRFTTLESRYETLFQRLSRFGLDDNRFDCSQCSLIWMANTMKAI-------YYKNQNKDQQTII----YPKCHQPYKLKDKFIHSLSSSDFQCPKPSIEKISIFILPNNTAQ-----------LICTA-SDVQSSVIWSQVFEPNDKDFLLIEQRKQILSNS-----AHSNKLVINKNQDID---VFLCTVTSLIGNASSTRLQISWPKYKTQFRLLNNSHRNVWNDPLTPMPGE-KYPKN------------YFFQPQFSLIEMISGVVGTFIATLIVFITMLRCIFYRIR 1481
             C  G ++C E  L   +P  +P    K+++++Q F ++  L+R N+S Y+     I ++TI +C L+AIE+  FS +  L  LDLS N L+ ++  TF+ L L  LRLD N  L L + +F+ L V SLS+  C L  L + V +P+  S  L  L LTSN  TTL++R+E  F+ LS   L  N F C  C L+W++ T++          ++  N D+  I+    +P C  P  L+ K I SLS+ DF C  P +  + +        Q           + C A    +  + W +  +    + + +   +Q+ S       +HS     +K++  D   +F C      GN S+  L + WP       L ++   N  N P+ P  G+ KY  N            YFF  +F+++E+I  VVGTF AT+++F+     ++ R R
Sbjct:   37 GCTYGSISCQEADLLHMLPNNLPNGIEKVIIVSQRF-DSQFLSRQNISSYTLPGVNIHELTIMHCGLRAIEAGTFSGLSSLTKLDLSKNSLSRIQGHTFSGLRLDLLRLDDNQGLTLDSEAFENLTVSSLSMQNCGLRSLSYEVFQPLVQSRSLTTLRLTSNSLTTLDARFEPFFRNLSFLSLARNPFVC-DCKLVWLSRTLQRKRRADSDDAFRRLNDDRLLIVPDDDHPVCESPNHLRGKHIVSLSTRDFFCGPPQMRALEVDFSDLRVGQSETFNMTGVVLIKCAAQGSPEMQLAWFRR-DRRGGEPIRLPGLRQVASGVVEVSISHSLFAKNSKSETEDAGQLFTCLGVDTYGNTSAD-LSLRWPALPLLSPLPSSPTSNNRN-PMEPSSGDSKYLNNDKGYFQSDRLDEYFFMKKFTILELIGAVVGTFTATILLFLMGYILLYMRHR 484

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BLAST of Ig-like domain-containing protein vs. Ensembl Cavefish
Match: lrrc4cb (leucine-rich repeat-containing protein 4C-like [Source:NCBI gene;Acc:103034014])

HSP 1 Score: 63.1586 bits (152), Expect = 7.619e-10
Identity = 76/311 (24.44%), Postives = 132/311 (42.44%), Query Frame = 3

Query:  447 QNCSLQAIESRAFSQIIYLETLDLS-FNKLTELEPFTFADL-NLKFLRLDGNLNLKLTANSFKELRVDXXXXXXXXXXXXPFTVLEPIS-TGLIQL-----------ILTSNRFTTLESRYE----------------TLFQRLSRFGLDDNRFDCSQCSLIWMANTMKAIYYKNQNKDQQTIIYPKCHQPYKLKDKFIHSLSSSDFQCPKPSIEK--ISIFILPNNTAQLICTASDVQSSVIWSQVFEPNDKDFLLIEQRKQILSNSAHSNKLVINKN----------QDIDVFLCTVTSLIGNASSTRL 1253
            +N  +++I S AF+++  L  LDL    +L+ +    F  L NL++L L G  NLK   N    +R+D L + G        TV+ P S  GL+ L           I+  N F  L+S  E                T  + L R  L  N ++C+ C ++W++      ++  +     T    +C+ P  LK ++I  L  S FQC  P I +    + +      +L C  + + +SV W     PN            +L++ A   ++ +  +          QD+  + C V++++GN S++ L
Sbjct:  157 RNNPIESIPSYAFNRLPSLRRLDLGELKRLSYVSDGAFEGLGNLRYLNL-GMCNLKEVPNIQPLVRLDELEMSGNQ-----LTVIRPGSFKGLVHLHKLWMMHAQVQIIERNSFDDLQSLGELNLAHNNLTFVPHDLFTPLRHLQRVHLHHNPWNCN-CDILWLS------WWLRETVPTNTSCCARCYSPPSLKGRYIGELDQSYFQCYAPVIVESPADLNVTEGTAVELKCRTNSL-TSVSW---LTPNGS----------VLTHGASKGRVTVQNDGTLNFTSVTMQDMGTYTCKVSNMLGNVSASVL 440

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BLAST of Ig-like domain-containing protein vs. Ensembl Cavefish
Match: lrrc4ba (leucine-rich repeat-containing protein 4B-like [Source:NCBI gene;Acc:103034410])

HSP 1 Score: 62.003 bits (149), Expect = 1.877e-9
Identity = 65/272 (23.90%), Postives = 112/272 (41.18%), Query Frame = 3

Query:  453 CSLQAIESRAFSQIIYLETLDLSFNKLTELEPFTFADL-NLKFLRLDGNLNLKLTANSFKELRVDXXXXXXXXXXXXPFTVLEPISTGLIQLILTSNRFTTLESRYETLFQRLSRFGLDDNRFDCSQCSLIWMANTMKAIYYKNQNKDQQTIIYPKCHQPYKLKDKFIHSLSSSDFQCPKPSIEK--ISIFILPNNTAQLICTASDVQSSVIWSQVFEPNDKDFLLIEQRKQILSNSAHSNKLVINKN--QDIDVFLCTVTSLIGNASSTRL 1253
            C L+ I +   + ++ LE L+LS N+L  + P +F  L +L+ L L  +    +  N+F +L+                         L +L L+ N   +L     T  Q+L R  L+ N + C+ C ++W++      ++  +     T    +CH P  LK K+I  L  S F C  P I +    + +     A+L C      +SV W     PN    L+     ++  +  H   L       +D   + C VT+  GN ++T +
Sbjct:  200 CGLKDIPN--LTPLVRLEELELSGNRLEIIRPGSFQGLESLRKLWLMHSQMTVIERNAFDDLK------------------------SLEELNLSHNSLHSLPHDLFTPLQKLERVHLNHNPWVCN-CDVLWLS------WWLKETVPSNTTCCARCHAPPYLKGKYIGELDQSHFTCYAPVIVEPPTDLNVTEGMAAELKCRTGTSMTSVNW---ITPNGT--LMTHGSYRVRISVLHDGTLNFTNVTLRDTGQYTCMVTNSAGNTTATAV 433

[Close]

Query:  453 CSLQAIESRAFSQIIYLETLDLSFNKLTELEPFTFADL-NLKFLRLDGNLNLKLTANSFKELRVDXXXXXXXXXXXXPFTVLEPISTGLIQLILTSNRFTTLESRYETLFQRLSRFGLDDNRFDCSQCSLIWMANTMKAIYYKNQNKDQQTIIYPKCHQPYKLKDKFIHSLSSSDFQCPKPSIEK--ISIFILPNNTAQLICTASDVQSSVIWSQVFEPNDKDFLLIEQRKQILSNSAHSNKLVINKN--QDIDVFLCTVTSLIGNASSTRL 1253
            C L+ I +   + ++ LE L+LS N+L  + P +F  L +L+ L L  +    +  N+F +L+                         L +L L+ N   +L     T  Q+L R  L+ N + C+ C ++W++      ++  +     T    +CH P  LK K+I  L  S F C  P I +    + +     A+L C      +SV W     PN    L+     ++  +  H   L       +D   + C VT+  GN ++T +
Sbjct:  200 CGLKDIPN--LTPLVRLEELELSGNRLEIIRPGSFQGLESLRKLWLMHSQMTVIERNAFDDLK------------------------SLEELNLSHNSLHSLPHDLFTPLQKLERVHLNHNPWVCN-CDVLWLS------WWLKETVPSNTTCCARCHAPPYLKGKYIGELDQSHFTCYAPVIVEPPTDLNVTEGMAAELKCRTGTSMTSVNW---ITPNGT--LMTHGSYRVRISVLHDGTLNFTNVTLRDTGQYTCMVTNSAGNTTATAV 433

[Close]

BLAST of Ig-like domain-containing protein vs. Ensembl Cavefish
Match: lrrc4ba (leucine-rich repeat-containing protein 4B-like [Source:NCBI gene;Acc:103034410])

HSP 1 Score: 61.2326 bits (147), Expect = 2.515e-9
Identity = 65/272 (23.90%), Postives = 112/272 (41.18%), Query Frame = 3

Query:  453 CSLQAIESRAFSQIIYLETLDLSFNKLTELEPFTFADL-NLKFLRLDGNLNLKLTANSFKELRVDXXXXXXXXXXXXPFTVLEPISTGLIQLILTSNRFTTLESRYETLFQRLSRFGLDDNRFDCSQCSLIWMANTMKAIYYKNQNKDQQTIIYPKCHQPYKLKDKFIHSLSSSDFQCPKPSIEK--ISIFILPNNTAQLICTASDVQSSVIWSQVFEPNDKDFLLIEQRKQILSNSAHSNKLVINKN--QDIDVFLCTVTSLIGNASSTRL 1253
            C L+ I +   + ++ LE L+LS N+L  + P +F  L +L+ L L  +    +  N+F +L+                         L +L L+ N   +L     T  Q+L R  L+ N + C+ C ++W++      ++  +     T    +CH P  LK K+I  L  S F C  P I +    + +     A+L C      +SV W     PN    L+     ++  +  H   L       +D   + C VT+  GN ++T +
Sbjct:  187 CGLKDIPN--LTPLVRLEELELSGNRLEIIRPGSFQGLESLRKLWLMHSQMTVIERNAFDDLK------------------------SLEELNLSHNSLHSLPHDLFTPLQKLERVHLNHNPWVCN-CDVLWLS------WWLKETVPSNTTCCARCHAPPYLKGKYIGELDQSHFTCYAPVIVEPPTDLNVTEGMAAELKCRTGTSMTSVNW---ITPNGT--LMTHGSYRVRISVLHDGTLNFTNVTLRDTGQYTCMVTNSAGNTTATAV 420

[Close]

BLAST of Ig-like domain-containing protein vs. Ensembl Cavefish
Match: lrrc4bb (leucine rich repeat containing 4Bb [Source:ZFIN;Acc:ZDB-GENE-091116-44])

HSP 1 Score: 60.077 bits (144), Expect = 6.764e-9
Identity = 71/283 (25.09%), Postives = 120/283 (42.40%), Query Frame = 3

Query:  447 QNCSLQAIESRAFSQIIYLETLDLS-FNKLTELEPFTFADL-NLKFLRLDGNLNLKLTANSFKELRVDXXXXXX----XXXXXXPFTVLEPIS----TGLIQLILTSNRFTTLESRYETLFQRLSRFGLDDNRFDCSQCSLIWMANTMKAIYYKNQNKDQQTIIYPKCHQPYKLKDKFIHSLSSSDFQCPKPSIEK--ISIFILPNNTAQLICTASDVQSSVIWSQVFEPNDKDFLLIEQRKQILSNSAHSNKLVINK--NQDIDVFLCTVTSLIGNASSTRL 1253
            +N  ++ + + AF ++  L  LDL    KL+ +    F  L NL+FL L G   LK   N    +R++ L L G         LP +++E  +      L +L L+ N   +L     T  Q+L R  L+ N + C+ C ++W++      ++  +     +    +CH P   K ++I  L   DF C  P I +    + +     A+L C      +SV W     PN    L+     ++  +  H   L       QD   + C VT+  GN ++T +
Sbjct:  148 RNNPIETLPAYAFHRVPSLRRLDLGELRKLSFISEAAFEGLVNLRFLNL-GMCGLKDVPNLTPLVRLEELELSGNQLGLVAQSLPLSLIERNAFDDLKNLEELNLSHNSLHSLPHDLFTPLQQLERVHLNHNPWVCN-CDVLWLS------WWLKETVPDNSTCCARCHAPPGTKGRYIGDLDQRDFTCYAPVIVEPPTDLNVTEGMAAELKCRTGTSMTSVNW---LTPNGT--LMTHGAYKVRISVLHDGTLNFTNVTMQDTGPYTCMVTNSAGNTTATAV 417

[Close]

BLAST of Ig-like domain-containing protein vs. Ensembl Sea Lamprey
Match: pxdn (peroxidasin [Source:ZFIN;Acc:ZDB-GENE-140415-2])

HSP 1 Score: 71.633 bits (174), Expect = 4.398e-13
Identity = 61/275 (22.18%), Postives = 108/275 (39.27%), Query Frame = 3

Query:  459 LQAIESRAFSQIIYLETLDLSFNKLTELEPFTFADLNLKFLRLDGNLNLKLTANSFKELRVDXXXXXXXXXXXXPFTVLEPISTGLIQLILTSNRFTTLESRYETLFQRLSRFGLDDNRFDCSQCSLIWMANTMKAIYYKNQNKDQQTIIYPKCHQPYKLKDKFIHSLSSSDFQCPKPSI--EKISIFILPNNTAQLICTA-SDVQSSVIWSQVFEPNDKDFLLIE-QRKQILSNSAHSNKLVIN--KNQDIDVFLCTVTSLIGNASSTRLQISW 1265
            +Q+I+  AF  ++ LE L + FN +  LEP TF DL                                                 L +L L +NR + + +   T    L R  LD NR  C  C L+W+A  ++A           T+    C  P +L+ + + S+++ +F C  P I  E   + + P NT  L C A  + + ++IW      N  +  + E +R+ +L +      L+I   ++ D   + C   ++ G   +  + + +
Sbjct:   59 IQSIDRHAFKGLVSLEQLYIHFNHIEVLEPNTFVDL-----------------------------------------------PKLERLFLHNNRLSRIATGTFTQLSSLRRLRLDSNRLVCD-CELVWLAELLRAFAGSG-----GTLAAATCEHPRRLQGRSVSSITAQEFHCESPRITSEPHDVDVTPGNTVYLRCRAEGNPKPAIIWLH----NSNEIAMAEDERRNLLQDGT----LMIRDTRHTDQGTYQCMARNVAGEVKAPEVVLRY 272

[Close]

BLAST of Ig-like domain-containing protein vs. Ensembl Sea Lamprey
Match: lrrc4ba (leucine rich repeat containing 4Ba [Source:ZFIN;Acc:ZDB-GENE-080327-25])

HSP 1 Score: 56.9954 bits (136), Expect = 1.252e-8
Identity = 69/282 (24.47%), Postives = 111/282 (39.36%), Query Frame = 3

Query:  453 CSLQAIESRAFSQIIYLETLDLSFNKLTELEPFTFADL-NLKFLRLDGNLNLKLTANSFKELRVDXXXXXXXXXXXXPFTVLEPISTGLIQLILTSNRFTTLESRYETLFQRLSRFGLDDNRFDCSQCSLIWMANTMKAIYYKNQNKDQQTIIYPKCHQPYKLKDKFIHSLSSSDFQCPKPSIE--KISIFILPNNTAQLICTASDVQSSVIWSQVFEPNDKDFLLIEQRKQILSNSAHSNKLVINKN--QDIDVFLCTVTSLIGNA-SSTRLQISWPKYKT 1280
            C+L+ +     S ++ LE L+LS N++  L P +F  L NL+ L +  +    +  N+F EL+                         L +L L  N   +L     +  Q+L R  L  N + C  C ++W++      ++  +N         +C  P   K   +  L SS F C  P IE     + I     A+L C A    SSV W     PN     +     +I  +  H   L       QD  ++ C V + +GN+ +S  L ++ P   T
Sbjct:  162 CNLREVPK--LSPLVRLEELELSGNRIEILRPGSFQGLANLRKLWIMHSEVRLVERNAFDELQ------------------------SLKELNLAHNSLMSLPHDLFSPLQKLERVHLHHNPWTC-DCDILWLS------WWLRENVPNNATCCARCALPADRKAINLWELDSSRFTCYPPLIEVPPSDVNISEGMAAELRCRAPSSASSVTW---ITPNGTS--MTHGSYKIRISVLHDGTLNFTNVTVQDTGIYTCLVANSVGNSTASATLNVTAPDTGT 405

[Close]

BLAST of Ig-like domain-containing protein vs. Ensembl Medaka
Match: lrrc4bb (leucine-rich repeat-containing protein 4B [Source:NCBI gene;Acc:101159140])

HSP 1 Score: 64.3142 bits (155), Expect = 3.874e-10
Identity = 72/278 (25.90%), Postives = 114/278 (41.01%), Query Frame = 3

Query:  453 CSLQAIESRAFSQIIYLETLDLSFNKLTELEPFTFADL-NLKFLRLDGNLNLKLTANSFKELRVDXXXXXXXXXXXXPFTVLEPISTGLIQLILTSNRFTTLESRYETLFQRLSRFGLDDNRFDCSQCSLIWMANTMKAIYYKNQNKDQQTIIYPKCHQPYKLKDKFIHSLSSSDFQCPKPSIEK--ISIFILPNNTAQLICTASDVQSSVIWSQVFEPNDKDFLLIEQRKQILSNSAHSNKLVINK--NQDIDVFLCTVTSLIGN-ASSTRLQISWP 1268
            C L+ I +   + ++ LE L+LS N+L  + P +F  L +L+ L L  +    +  N+F EL+                         L +L L+ N   +L     T   +L R  L+ N + C+ C ++W++  +K     N      T    +CH P  LK K+I  L  S F C  P I +    + +     A+L C      +SV W   F PN    L+     ++  +  H   L       QD   + C VT+  GN  +S  L +S P
Sbjct:  199 CGLKDIPN--LTPLVKLEELELSGNQLGIVRPGSFQGLVSLRKLWLMHSRVSVIERNAFDELK------------------------SLEELNLSHNSLHSLPHDLFTPLHQLERVHLNHNPWVCN-CDVLWLSWWLKETVPSN------TTCCARCHAPPGLKGKYIGELDQSHFPCYAPVIVEPPTDLNVTEGMAAELKCRTGTSMTSVNW---FTPNGT--LMTHGSYRVRISVLHDGTLNFTNVTVQDTGQYTCMVTNSAGNTTASAVLNVSAP 438

[Close]

BLAST of Ig-like domain-containing protein vs. Ensembl Medaka
Match: lrrc4.2 (leucine rich repeat containing 4 [Source:NCBI gene;Acc:101167534])

HSP 1 Score: 62.003 bits (149), Expect = 1.557e-9
Identity = 102/452 (22.57%), Postives = 170/452 (37.61%), Query Frame = 3

Query:  453 CSLQAIESRAFSQIIYLETLDLSFNKLTELEPFTFADL-NLKFLRLDGNLNLKLTANSFKELRVDXXXXXXXXXXXXPFTVLEPISTGLIQLILTSNRFTTLESRYETLFQRLSRFGLDDNRFDCSQCSLIWMANTMKAIYYKNQNKDQQTIIYPKCHQPYKLKDKFIHSLSSSDFQCPKPSI--EKISIFILPNNTAQLICTASDVQSSVIWSQVFEPNDKDFLLIEQRKQILSNSAHSNKLVINKN---------QDIDVFLCTVTSLIGNA-SSTRLQISWPKYKTQFRLLNNSHRNVWN-------DPL---TPMPGEKYPKN-YFFQPQF------------------------------SLIEMISG---VVGTFIATLIVFITMLRCIFYRIRLFSKNSQLRDHQLSLTSSKKDKRKQYMTYEPPV-------YSDSQTYDIPTL 1616
            C+L+ +     S ++ LE L++S N   EL+P+ F  L NL+ L +  +    +  N+F ++                        T L++L L  N  ++L     T  Q L    L  N + C  C ++W++  ++      +N    +    +CH P  ++ + +  +  + FQC  P I      + I     A+L C  +   SSV W            L+     +   SAH    V+N            D  ++ C V+++ GN+ +S  L IS  +       LN S+ + +        DP    TP P    P +   FQP F                              SL EM+     ++G F+A  +V   ML   FY++R   K  Q R    ++ +++  +  Q     PPV        SD     +PTL
Sbjct:  206 CNLRELPH--LSPLVGLEELEISDNVFPELKPWAFHGLKNLRKLWIMNSAITTIERNAFDDI------------------------TALVELNLAHNNLSSLPHNLFTPLQYLVELHLHHNPWSC-DCDVVWLSAWLR------ENIPTNSTCCGRCHTPIHIRGRHLVEIDQTTFQCSAPFILDAPRDLNISAARVAELRCRTA-AMSSVRW------------LLPNGTVLTHGSAHPRISVLNDGTLNFSNVLPSDTGIYTCMVSNMAGNSNASAYLNISNAE-------LNTSNLSYFTTVTVEVLDPTVEETPKPKPTVPASPSVFQPVFISTPTVLFQNTQTPRQVSVPSPRAPAEPAASLDEMMKTTKIIIGCFVAVTLVAAAML-IAFYKLR---KRHQQRS---TVAAARTIEIIQMEEQVPPVPPTSRSSGSDDTGLALPTL 597

[Close]

BLAST of Ig-like domain-containing protein vs. Ensembl Medaka
Match: lrrc4cb (leucine rich repeat containing 4C [Source:NCBI gene;Acc:101160634])

HSP 1 Score: 58.5362 bits (140), Expect = 2.209e-8
Identity = 75/311 (24.12%), Postives = 130/311 (41.80%), Query Frame = 3

Query:  447 QNCSLQAIESRAFSQIIYLETLDLS-FNKLTELEPFTFADL-NLKFLRLDGNLNLKLTANSFKELRVDXXXXXXXXXXXXPFTVLEPIS-TGL---------------------------IQLILTSNRFTTLESRYETLFQRLSRFGLDDNRFDCSQCSLIWMANTMKAIYYKNQNKDQQTIIYPKCHQPYKLKDKFIHSLSSSDFQCPKPSIEK--ISIFILPNNTAQLICTASDVQSSVIWSQVFEPNDKDFLLIEQRKQILSNSAHSNKL-VINKN---------QDIDVFLCTVTSLIGNASSTRL 1253
            +N  +++I S AF+++  L  LDL    +L+ +    F DL NL++L L G  NLK   N    ++++ L + G        TV++P S TGL                           ++L L  N  T L     T    L R  L  N ++C+ C ++W++      ++  +     T    +CH P   K ++I  L  S FQC  P I +    + +     A+L C  + + +S+ W     PN            ++++ A+  +L V+N           QD   + C V++  GN S++ +
Sbjct:  157 RNNPIESIPSYAFNRVPSLRRLDLGELKRLSYISELAFKDLSNLRYLNL-GMCNLKEIPNIIPLVKLEELEMSGNQ-----LTVIKPSSFTGLANLQKLWMMHSQVQTIERNSFDDLQSLVELNLAHNNLTFLPHDLFTPLHHLERVHLHHNPWNCN-CDILWLS------WWLKETVPANTSCCARCHTPSVFKGRYIGELDHSYFQCDVPVIVEPPSDLNVTEGMGAELKCRTNSM-TSISW---LTPNGS----------MVTHGAYKVRLSVLNDGTLNFTSVTMQDTGTYTCMVSNTAGNISASAV 440

[Close]

BLAST of Ig-like domain-containing protein vs. Ensembl Medaka
Match: slit1a (slit guidance ligand 1 [Source:NCBI gene;Acc:101164917])

HSP 1 Score: 58.151 bits (139), Expect = 3.375e-8
Identity = 73/303 (24.09%), Postives = 117/303 (38.61%), Query Frame = 3

Query:  225 NKKIICPPVCNQMACNMGILTCSETGLSEIPKLIPPKTNKILLINQDFSEAGTLTRLNLSDYSSXXXXXXXXXXQNCSLQAIESRAFSQIIYLETLDLSFNKLTELEPFTFADLNLKFLRLDGNLNLKLTANSFKELRVDXXXXXXXXXXXXPFTVLEPIS-----------------TGLIQLILTS---NRFTTLESRYETLFQRLSRFGLDDNRFDCSQCSLIWMANTMKAIYYKNQNKDQQTIIYPKCHQPYKLKDKFIHSLSSSDFQCPKPSIEKISIFILPNNTAQLICTASDVQSS 1073
            N   +CPP C    C   ++ CS   L++IP+ IP  T+++ L N + +                            SL A  + AF  +  L+ ++LS NK+TE+E  TF   +         + L LTAN    +R               F  LE +                  TGL  + L S   N+ TT+        Q LS   L  N F+C  C L W+ + +++      N        P+C +P  LK+  +  ++  DF+C +   E+ S    P   ++  C  + V+ S
Sbjct:  511 NSDPVCPPKCR---CESNVVDCSNLKLTKIPEHIPSSTSELRLNNNEIT----------------------------SLDA--NGAFKNLAQLKKINLSNNKITEIEDGTFEGASAV-------IELHLTANQIDSVRSGM------------FRGLEGLRMLMLRNNKISCVHNDSFTGLHNVRLLSLYDNQLTTITPGAFDTLQTLSTLNLLANSFNC-DCRLAWLGDWLRSRKIVTGN--------PRCQRPAFLKEIPLQDVALPDFRCDE-GQEESSCIPRPQCPSECTCLETVVRCS 751

[Close]

BLAST of Ig-like domain-containing protein vs. Ensembl Medaka
Match: slit1a (slit guidance ligand 1 [Source:NCBI gene;Acc:101164917])

HSP 1 Score: 57.7658 bits (138), Expect = 3.966e-8
Identity = 73/303 (24.09%), Postives = 117/303 (38.61%), Query Frame = 3

Query:  225 NKKIICPPVCNQMACNMGILTCSETGLSEIPKLIPPKTNKILLINQDFSEAGTLTRLNLSDYSSXXXXXXXXXXQNCSLQAIESRAFSQIIYLETLDLSFNKLTELEPFTFADLNLKFLRLDGNLNLKLTANSFKELRVDXXXXXXXXXXXXPFTVLEPIS-----------------TGLIQLILTS---NRFTTLESRYETLFQRLSRFGLDDNRFDCSQCSLIWMANTMKAIYYKNQNKDQQTIIYPKCHQPYKLKDKFIHSLSSSDFQCPKPSIEKISIFILPNNTAQLICTASDVQSS 1073
            N   +CPP C    C   ++ CS   L++IP+ IP  T+++ L N + +                            SL A  + AF  +  L+ ++LS NK+TE+E  TF   +         + L LTAN    +R               F  LE +                  TGL  + L S   N+ TT+        Q LS   L  N F+C  C L W+ + +++      N        P+C +P  LK+  +  ++  DF+C +   E+ S    P   ++  C  + V+ S
Sbjct:  510 NSDPVCPPKCR---CESNVVDCSNLKLTKIPEHIPSSTSELRLNNNEIT----------------------------SLDA--NGAFKNLAQLKKINLSNNKITEIEDGTFEGASAV-------IELHLTANQIDSVRSGM------------FRGLEGLRMLMLRNNKISCVHNDSFTGLHNVRLLSLYDNQLTTITPGAFDTLQTLSTLNLLANSFNC-DCRLAWLGDWLRSRKIVTGN--------PRCQRPAFLKEIPLQDVALPDFRCDE-GQEESSCIPRPQCPSECTCLETVVRCS 750

[Close]

BLAST of Ig-like domain-containing protein vs. Planmine SMEST
Match: SMESG000001734.1 (SMESG000001734.1)

HSP 1 Score: 1009.98 bits (2610), Expect = 0.000e+0
Identity = 519/522 (99.43%), Postives = 521/522 (99.81%), Query Frame = 3

Query:  126 MLNLLTLSKTFLFYAQWILLSTTSSANIDFSHDNKKIICPPVCNQMACNMGILTCSETGLSEIPKLIPPKTNKILLINQDFSEAGTLTRLNLSDYSSXXXXXXXXXXQNCSLQAIESRAFSQIIYLETLDLSFNKLTELEPFTFADLNLKFLRLDGNLNLKLTANSFKELRVDXXXXXXXXXXXXPFTVLEPISTGLIQLILTSNRFTTLESRYETLFQRLSRFGLDDNRFDCSQCSLIWMANTMKAIYYKNQNKDQQTIIYPKCHQPYKLKDKFIHSLSSSDFQCPKPSIEKISIFILPNNTAQLICTASDVQSSVIWSQVFEPNDKDFLLIEQRKQILSNSAHSNKLVINKNQDIDVFLCTVTSLIGNASSTRLQISWPKYKTQFRLLNNSHRNVWNDPLTPMPGEKYPKNYFFQPQFSLIEMISGVVGTFIATLIVFITMLRCIFYRIRLFSKNSQLRDHQLSLTSSKKDKRKQYMTYEPPVYSDSQTYDIPTLPVNQSTLGHFIDFKTQQTLYSEKNQ 1691
            MLNLL LSKTFLFYAQWILLSTTSSANI+FSHDNKKIICPPVCNQMACNMGILTCSETGLSEIPKLIPPKTNKILLINQDFSEAGTLTRLNLSDYSSKKHKITKITIQNCSLQAIESRAFSQIIYLETLDLSFNKLTELEPFTFADLNLKFLRLDGNLNLKLTANSFKELRVDSLSLLGCHLSHLPFTVLEPISTGLIQLILTSNRFTTLESRYETLFQRLSRFGLDDNRFDCSQCSLIWMANTMK+IYYKNQNKDQQTIIYPKCHQPYKLKDKFIHSLSSSDFQCPKPSIEKISIFILPNNTAQLICTASDVQSSVIWSQVFEPNDKDFLLIEQRKQILSNSAHSNKLVINKNQDIDVFLCTVTSLIGNASSTRLQISWPKYKTQFRLLNNSHRNVWNDPLTPMPGEKYPKNYFFQPQFSLIEMISGVVGTFIATLIVFITMLRCIFYRIRLFSKNSQLRDHQLSLTSSKKDKRKQYMTYEPPVYSDSQTYDIPTLPVNQSTLGHFIDFKTQQTLYSEKNQ
Sbjct:    1 MLNLLILSKTFLFYAQWILLSTTSSANIEFSHDNKKIICPPVCNQMACNMGILTCSETGLSEIPKLIPPKTNKILLINQDFSEAGTLTRLNLSDYSSKKHKITKITIQNCSLQAIESRAFSQIIYLETLDLSFNKLTELEPFTFADLNLKFLRLDGNLNLKLTANSFKELRVDSLSLLGCHLSHLPFTVLEPISTGLIQLILTSNRFTTLESRYETLFQRLSRFGLDDNRFDCSQCSLIWMANTMKSIYYKNQNKDQQTIIYPKCHQPYKLKDKFIHSLSSSDFQCPKPSIEKISIFILPNNTAQLICTASDVQSSVIWSQVFEPNDKDFLLIEQRKQILSNSAHSNKLVINKNQDIDVFLCTVTSLIGNASSTRLQISWPKYKTQFRLLNNSHRNVWNDPLTPMPGEKYPKNYFFQPQFSLIEMISGVVGTFIATLIVFITMLRCIFYRIRLFSKNSQLRDHQLSLTSSKKDKRKQYMTYEPPVYSDSQTYDIPTLPVNQSTLGHFIDFKTQQTLYSEKNQ 522

[Close]

BLAST of Ig-like domain-containing protein vs. Planmine SMEST
Match: SMESG000025920.1 (SMESG000025920.1)

HSP 1 Score: 261.151 bits (666), Expect = 1.623e-78
Identity = 182/511 (35.62%), Postives = 280/511 (54.79%), Query Frame = 3

Query:  213 FSHDNKKIICPPVCNQMACNMGILTCSETGLSEIPKLIPPKTNKILLINQDFSEAGTLTRLNLSDYSSXXXXXXXXXXQNCSLQAIESRAFSQIIYLETLDLSFNKLTELEPFTFADLNLKFLRLDGNLNLKLTANSFKELRVDXXXXXXXXXXXXPFTVLEPISTGLIQLILTSNRFTTLESRYETLFQRLSRFGLDDNRFDCSQCSLIWMANTMKAIYYKNQN-----KDQQTIIYPKCHQPYKLKDKFIHSLSSSDFQCPKPSIEKISIFILPNNTAQLI--CTASDVQSSVIWSQVFEPNDKDFLLIEQRKQILSNSAHSNKLVINKNQDIDVFLCTVTSLIGNASSTRLQISWPKYKTQFRLLNNSHRNVWNDPLTPMPGEKYPKNYFFQPQFSLIEMISGVVGTFIATLIVFITMLRCIFYRI--------------RLFSKNSQLRDHQLSLTSSKKD-KRKQYMTYEPPVYSDSQTYDIPTLPVNQSTLGHFIDFKTQQTLYS 1679
            F H +    CP  CN+ AC+ G+L+CS++GL+ IP ++PP  + + LINQDFS+AG LT  N+S Y   K KI+KITIQ+C L  I   +FS + YLE LDLS+N+L ++ P TF  LNLKFLRLDGN+NLK   +SF++  +  LSL+ C L  L F  L+PI   L +LIL+SN   T++SRY+ LF RL    LD+N F+C+ C L W+A T+ +  +KN N     K Q   ++PKC++P  L ++F+H +   +F C  PSI+ I + I   N  +LI  C +      V+W Q  +  D             SN A SN +V++  +      C + +  GN  ST++ I WP+    F  ++     V     +P       K     PQFSL+E+++ + GTF+    +F+ ++R +  R               +  +K+S +  + L++ ++  + +  +Y       + +SQTYD+P  P +      FIDFKT Q +++
Sbjct:   19 FFHKSSSFNCPNFCNKDACDNGVLSCSKSGLTSIPNVLPPNVDNVQLINQDFSQAGELTYSNISSYGPPKFKISKITIQHCRLVGIAPESFSHLNYLEILDLSYNRLAQILPRTFESLNLKFLRLDGNMNLKFHCSSFQKSIIRHLSLVNCSLKILDFCTLKPIIGVLKKLILSSNLLQTIDSRYDFLFNRLLVLRLDNNLFNCADCRLKWLAKTL-STRFKNYNFSIEKKIQIDKVFPKCNRPTFLAERFLHQIDEQEFSCRTPSIKSIDLKI--ENIEKLILSCHSQSKNDYVMWYQDSKIED-------------SNRAQSN-IVLHSGKAYRQLKCLINNPNGNI-STKINIGWPR----FVQIDEPESTV-----SPPDETNSNKGVLHIPQFSLLELLAAIFGTFMIFFFIFVCVIRYLLNRKENHYVQYPVIIDCNKYINKSSLIDHNNLTINATYPECELIRYDVSSSTSFCNSQTYDVPVYPNSV-----FIDFKTHQQIHT 497

[Close]

BLAST of Ig-like domain-containing protein vs. Planmine SMEST
Match: SMESG000035909.1 (SMESG000035909.1)

HSP 1 Score: 226.098 bits (575), Expect = 2.036e-65
Identity = 163/488 (33.40%), Postives = 257/488 (52.66%), Query Frame = 3

Query:  240 CPPVCNQMACNMGILTCSETGLSEIPKLIPPKTNKILLINQDFSEAGTLTRLNLSDYSSXXXXXXXXXXQNCSLQAIESRAFSQIIYLETLDLSFNKLTELEPFTFADLNLKFLRLDGNLNLKLTANSFKELRVDXXXXXXXXXXXXPFTVLEPISTGLIQLILTSNRFTTLESRYETLFQRLSRFGLDDNRFDCSQCSLIWMANTM--KAIYYKNQNKDQQTIIYPKCHQPYKLKDKFIHSLSSSDFQCPKPSIEKISIFILPNNTAQLICTASDVQSSVIWSQVFEPNDKDFLLIEQRKQILSNS---AHSNKLVINKNQDIDVFLCTVTSLIGNASSTRLQISWPK--YKTQFRLLNNSHRNVWNDPLTPMPGEKYPKNYFFQPQFSLIEMISGVVGTFIATLIVFITMLRCIFYRIRLFSKNSQLRDHQLSLTSSKKDKRKQYMTYEPPVYSDSQTYDIPTLP-----VNQSTLGHFIDFKTQQ 1667
            CP VC +MAC  GILTC + GL  IP+ +P  T K+LL+   F     ++  N + Y+        +   NCS+ +IE   F ++  L+TLDLS NK+  ++P+TF+ L L FLRLD N N++L  NSF  L+V  LSL  C L+ L +     +   L +L LT N    +++++  +F+ L    L++N  DCS C + W++  +  +    K++ KD       +C  P  L +K IH L+ S + C  PS+ ++ +FIL N++A+L C  +  Q+S I    F+          +  +IL NS    +++ + I +    D + C+  +L GN S+  ++I WP+  +KT +     + +         +P   Y K++FFQ QF+L+EMI GVVGTF  TL++F+ + RC   + R                   K+ RK+ + YE  +YSDSQTYDIP  P       Q++  H++DFK  Q
Sbjct:   60 CPSVCQEMACKTGILTCPDGGLKSIPEFLPASTTKVLLVGHIFDNP-QISGANFTKYAVFNIAKLTLL--NCSINSIEPFTFLRMTQLQTLDLSKNKIKLIQPYTFSGLTLSFLRLDENKNIELRKNSFSGLKVKKLSLNDCDLNDLNYDSFADLIGNLERLTLTQNNLRVIDAKFTNIFRSLIELELNNNPLDCS-CDMKWLSGVLRHRQTIQKDKKKDDNL---ARCATPQDLTNKLIHLLNDSSYICGTPSLVELDLFILSNDSAKLSCVTARNQNSRIMWHFFD---------TEGYRILQNSMSQMYNSTIKIKRKYQTDKYFCSAHNLNGN-STIEIRIKWPQLYHKTTYYPTGVNKK---------LPHPSYDKDFFFQRQFTLLEMIGGVVGTFTGTLLLFLLIYRCFIQKHR-------------------KESRKRKL-YETVIYSDSQTYDIPHQPYYPIHAYQTSPAHYLDFKNPQ 501

[Close]

BLAST of Ig-like domain-containing protein vs. Planmine SMEST
Match: SMESG000033458.1 (SMESG000033458.1)

HSP 1 Score: 224.557 bits (571), Expect = 7.151e-65
Identity = 169/494 (34.21%), Postives = 257/494 (52.02%), Query Frame = 3

Query:  240 CPPVCNQMACNMGILTCSETGLSEIPKLIPPKTNKILLINQDFSEAGTLTRLNLSDYSSXXXXXXXXXXQNCSLQAIESRAFSQIIYLETLDLSFNKLTELEPFTFADLNLKFLRLDGNLNLKLTANSFKELRVDXXXXXXXXXXXXPFTVLEPISTGLIQLILTSNRFTTLESRYETLFQRLSRFGLDDNRFDCSQCSLIWMANTMKAIYYKNQNKDQQTIIY---PKCHQPYKLKDKFIHSLSSSDFQCPKPSIEKISIFILPNNTAQLICTASDVQSS-VIWSQVFEPNDKDFLLIEQRKQILSNSAHSNKLVINKNQDIDVFLCTVTSLIGNASSTRLQISWPKYKTQF---------RLLN--NSHRNVWNDPLTPMPGEKYPKNYFFQPQFSLIEMISGVVGTFIATLIVFITMLRCIFYRIRLFSKNSQLRDHQLSLTSSKKDKRKQYMTYEPPVYSDSQTYDIPTL-PVNQSTLGHFIDFKTQQTL 1673
            CP +CNQ AC + +L C   GL +IP   P    K++L NQ+F     LT  NLS Y S++  + K+TI NCSL +IES AFS +IYL+ LDLS N+L  + P TF  L+LK L LD N NL+L  +SF+ L V SLS+  CHL  L    ++ IS  L  L L  NR   L + ++ LF+ L    L++N F+CS C L W+A T++    +  N  + +++    P C  P  LK   I +LS   FQC  P +++I I +    TA++ C + D+ +S V W   +  +   +   +Q     ++  +   ++++K  + D + C + +  GNA +  ++I WP    ++           +N  N   N+    +     +K   NY +  Q++ IEM+  + GTFI TL+ FI +   I YR     KNS+               +     YE  VYS+SQTYD+P + P ++S  G  +DFKTQQ +
Sbjct:   35 CPELCNQGACKLTMLLCETPGLLQIPMNPPRGIQKVILSNQNFLYP-RLTYTNLSRYGSEEIILKKLTISNCSLTSIESEAFSHLIYLQELDLSSNRLLFIYPNTFKSLSLKTLVLDSNRNLQLAKDSFRGLVVQSLSMKDCHLKILTHESIKQISGYLTTLNLADNRLEYLSNDFDLLFRGLDNLNLENNPFNCS-CQLKWLALTLQTRTKRRDNSPKHSLLRLTNPVCEYPKNLKGSSIENLSIVSFQCQIPKLQRIDIKVTSEITAEISCISDDMSNSQVKWRYRYNLSPLFYRYPDQ-----NSGLNQASIIVSKKSEFDFYSCLIINENGNA-TVDIKIKWPTLNKEYVESPIKSPPNTVNQFNLRNNITKSSVILKEFDKLHVNYLWIKQYTFIEMVLAICGTFIITLVTFILLYVVINYR----RKNSR--------------SKNILKGYEVGVYSESQTYDVPQMSPYHESNTGRLLDFKTQQEI 502

[Close]

BLAST of Ig-like domain-containing protein vs. Planmine SMEST
Match: SMESG000026559.1 (SMESG000026559.1)

HSP 1 Score: 215.312 bits (547), Expect = 1.371e-61
Identity = 158/475 (33.26%), Postives = 252/475 (53.05%), Query Frame = 3

Query:  240 CPPVCNQMACNMGILTCSETGLSEIPKLIPPKTNKILLINQDFSEAGTLTRLNLSDYSSXXXXXXXXXXQNCSLQAIESRAFSQIIYLETLDLSFNKLTELEPFTFADLNLKFLRLDGNLNLKLTANSFKELRVDXXXXXXXXXXXXPFTVLEPISTGLIQLILTSNRFTTLESRYETLFQRLSRFGLDDNRFDCSQCSLIWMANTM----KAIYYKNQNKDQQTIIYPKCHQPYKLKDKFIHSLSSSDFQCPKPSIEKISIFILPNNTAQLICTASDVQSS---VIWSQVFEPNDKDFLLIEQRKQILSN--SAHSNKLVINKNQDIDVFLCTVTSLIGNASSTRLQISWPKYKTQFRLLNNSHRNV------WNDPLTPMPGEK---YPKNYFFQPQFSLIEMISGVVGTFIATLIVFITMLRCIFYRIRLFSKNSQLRDHQLSLTSSKKDKRKQYMTYEPPVYSDSQTYDIP 1610
            CP VC++MAC  G+L C++ GL +IP ++  KT+KI++ NQ FS    LT  N S+Y    +KI KI +Q C L +I S  FS +  L  LDLS N L E+ P TF  L+L+FLRLD N  ++    SF+ L V  LSL  C+L+ L F V   IS  L +LILT+N+   ++ R+  LF+ L    +++N F+C+ C+L W+ + +    KAI   N +  ++     +C+ P ++K K I  L   DF C  P ++ I +F+   ++A+L C +     S   VIW            + E R   +    S+ +  L + +   ID + C + +   +  +  + I WP      + +NN+ +++       ND +  +P      + ++ F++ QF+L+EMI G+VGTF  T+I+F+ + R                   L++T  + DK+K Y++YE  + SDSQTYDIP
Sbjct:   26 CPSVCHEMACQTGVLACTDGGLLQIPPVLHQKTHKIIVSNQRFSSPH-LTYSNFSNYGPPNYKIEKIALQFCELVSIASNCFSHLTDLRVLDLSHNLLGEIPPDTFKALHLQFLRLDDNKMIQFHRFSFRGLNVAELSLFDCNLTELDFEVFSEISERLKKLILTNNKLNVIDKRFRILFENLPDLQINENPFNCT-CNLRWLNSVLVSRKKAI---NLSSSKRIPNQAQCNYPDRVKGKQIADLDLKDFDCDSPRLKLIDVFMTSTSSAKLTCISEPKAHSSPDVIW------------MAEHRNTYVPEIQSSENASLSVLRKSRIDKYKCVIKN-NNDYVTVVISIHWP-----VKRVNNASQSLNTLGVSPNDMIPYLPNANSTLHVRSVFYEKQFTLLEMIGGIVGTFTITMILFLCIYR------------------HLAMTMKRNDKKKWYLSYETAIGSDSQTYDIP 459

The following BLAST results are available for this feature:

BLAST of Ig-like domain-containing protein vs. Ensembl Human
BLAST of Ig-like domain-containing protein vs. Ensembl Celegans
BLAST of Ig-like domain-containing protein vs. Ensembl Fly
BLAST of Ig-like domain-containing protein vs. Ensembl Zebrafish
BLAST of Ig-like domain-containing protein vs. Ensembl Xenopus
BLAST of Ig-like domain-containing protein vs. Ensembl Mouse
BLAST of Ig-like domain-containing protein vs. UniProt/SwissProt
BLAST of Ig-like domain-containing protein vs. TrEMBL
BLAST of Ig-like domain-containing protein vs. Ensembl Cavefish
BLAST of Ig-like domain-containing protein vs. Ensembl Sea Lamprey
BLAST of Ig-like domain-containing protein vs. Ensembl Yeast
BLAST of Ig-like domain-containing protein vs. Ensembl Nematostella
BLAST of Ig-like domain-containing protein vs. Ensembl Medaka
BLAST of Ig-like domain-containing protein vs. Planmine SMEST

BLAST of Ig-like domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
LRRC4B	8.119e-10	23.70	leucine rich repeat containing 4B [Source:HGNC Sym...	[more]
LRRC4B	8.119e-10	23.70	leucine rich repeat containing 4B [Source:HGNC Sym...	[more]
LRRC4B	8.119e-10	23.70	leucine rich repeat containing 4B [Source:HGNC Sym...	[more]
SLIT1	2.882e-8	24.65	slit guidance ligand 1 [Source:HGNC Symbol;Acc:HGN...	[more]
LRRC4C	4.809e-8	23.51	leucine rich repeat containing 4C [Source:HGNC Sym...	[more]

BLAST of Ig-like domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 1


Match Name	E-value	Identity	Description
slt-1	7.470e-6	32.56	Slit homolog 1 protein [Source:UniProtKB/Swiss-Pr...	[more]

BLAST of Ig-like domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
sli	5.150e-9	23.89	gene:FBgn0264089 transcript:FBtr0330734	[more]
sli	6.077e-9	24.20	gene:FBgn0264089 transcript:FBtr0330733	[more]
sli	6.077e-9	24.20	gene:FBgn0264089 transcript:FBtr0330731	[more]
sli	1.226e-8	23.20	gene:FBgn0264089 transcript:FBtr0330730	[more]
sli	1.292e-8	23.20	gene:FBgn0264089 transcript:FBtr0330729	[more]

BLAST of Ig-like domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
lrrc4ba	9.643e-10	21.36	leucine rich repeat containing 4Ba [Source:ZFIN;Ac...	[more]
lrrc4ba	9.643e-10	21.36	leucine rich repeat containing 4Ba [Source:ZFIN;Ac...	[more]
lrrc4ba	3.762e-9	24.63	leucine rich repeat containing 4Ba [Source:ZFIN;Ac...	[more]
lrrc4ba	4.900e-9	24.81	leucine rich repeat containing 4Ba [Source:ZFIN;Ac...	[more]
lrrc4ba	5.013e-9	24.81	leucine rich repeat containing 4Ba [Source:ZFIN;Ac...	[more]

BLAST of Ig-like domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
lrrc4b	2.245e-9	24.07	leucine rich repeat containing 4B [Source:NCBI gen...	[more]
lrrc4	7.061e-8	22.89	leucine rich repeat containing 4 [Source:NCBI gene...	[more]
LINGO2	6.720e-7	25.66	leucine rich repeat and Ig domain containing 2 [So...	[more]
polr1e	1.003e-6	20.44	polymerase (RNA) I polypeptide E [Source:Xenbase;A...	[more]
polr1e	1.273e-6	20.44	polymerase (RNA) I polypeptide E [Source:Xenbase;A...	[more]

BLAST of Ig-like domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Lrrc4b	5.557e-10	24.44	leucine rich repeat containing 4B [Source:MGI Symb...	[more]
Slit1	2.613e-9	25.60	slit guidance ligand 1 [Source:MGI Symbol;Acc:MGI:...	[more]
Lrrc4c	6.131e-8	22.76	leucine rich repeat containing 4C [Source:MGI Symb...	[more]
Lrrc4c	6.131e-8	22.76	leucine rich repeat containing 4C [Source:MGI Symb...	[more]
Lrrc4c	6.131e-8	22.76	leucine rich repeat containing 4C [Source:MGI Symb...	[more]

BLAST of Ig-like domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|P0C192\|LRC4B_MOUSE	3.887e-9	24.44	Leucine-rich repeat-containing protein 4B OS=Mus m...	[more]
sp\|Q9NT99\|LRC4B_HUMAN	3.899e-9	23.70	Leucine-rich repeat-containing protein 4B OS=Homo ...	[more]
sp\|P0CC10\|LRC4B_RAT	4.093e-9	24.44	Leucine-rich repeat-containing protein 4B OS=Rattu...	[more]
sp\|P24014\|SLIT_DROME	6.091e-8	24.20	Protein slit OS=Drosophila melanogaster OX=7227 GN...	[more]
sp\|Q9HCJ2\|LRC4C_HUMAN	2.310e-7	23.51	Leucine-rich repeat-containing protein 4C OS=Homo ...	[more]

BLAST of Ig-like domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A5P8I4L0	1.751e-57	33.26	PXDN-like protein OS=Schmidtea mediterranea OX=793...	[more]
I1ZIL5	9.933e-57	34.21	Slit-2 OS=Schmidtea mediterranea OX=79327 PE=2 SV=...	[more]
A0A0R3TNY6	3.681e-32	29.87	Ig-like domain-containing protein OS=Rodentolepis ...	[more]
W6U6F3	5.024e-31	30.09	Immunoglobulin superfamily member OS=Echinococcus ...	[more]
A0A068YC11	7.821e-30	30.02	Variable lymphocyte receptor OS=Echinococcus multi...	[more]

BLAST of Ig-like domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
lrrc4cb	7.619e-10	24.44	leucine-rich repeat-containing protein 4C-like [So...	[more]
lrrc4ba	1.877e-9	23.90	leucine-rich repeat-containing protein 4B-like [So...	[more]
lrrc4ba	1.877e-9	23.90	leucine-rich repeat-containing protein 4B-like [So...	[more]
lrrc4ba	2.515e-9	23.90	leucine-rich repeat-containing protein 4B-like [So...	[more]
lrrc4bb	6.764e-9	25.09	leucine rich repeat containing 4Bb [Source:ZFIN;Ac...	[more]

BLAST of Ig-like domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 2


Match Name	E-value	Identity	Description
pxdn	4.398e-13	22.18	peroxidasin [Source:ZFIN;Acc:ZDB-GENE-140415-2]	[more]
lrrc4ba	1.252e-8	24.47	leucine rich repeat containing 4Ba [Source:ZFIN;Ac...	[more]

BLAST of Ig-like domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Ig-like domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Ig-like domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
lrrc4bb	3.874e-10	25.90	leucine-rich repeat-containing protein 4B [Source:...	[more]
lrrc4.2	1.557e-9	22.57	leucine rich repeat containing 4 [Source:NCBI gene...	[more]
lrrc4cb	2.209e-8	24.12	leucine rich repeat containing 4C [Source:NCBI gen...	[more]
slit1a	3.375e-8	24.09	slit guidance ligand 1 [Source:NCBI gene;Acc:10116...	[more]
slit1a	3.966e-8	24.09	slit guidance ligand 1 [Source:NCBI gene;Acc:10116...	[more]

BLAST of Ig-like domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000001734.1	0.000e+0	99.43	SMESG000001734.1	[more]
SMESG000025920.1	1.623e-78	35.62	SMESG000025920.1	[more]
SMESG000035909.1	2.036e-65	33.40	SMESG000035909.1	[more]
SMESG000033458.1	7.151e-65	34.21	SMESG000033458.1	[more]
SMESG000026559.1	1.371e-61	33.26	SMESG000026559.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30017278 ID=SMED30017278|Name=Ig-like domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=2231bp
GAACCAGATTTACGGATTTATGAAATATAGATTCCTTTGTCAATTAGACA
AGTCATTGAAATGTTTATGTATGGATATCAATTTAGTAATATTATTTTAT
TTACTAAATGCCCATAAATTATGAAATGTTGAATTTGTTGACACTGTCGA
AAACATTTCTTTTCTATGCTCAATGGATTCTTCTATCAACCACGTCCAGT
GCAAACATTGATTTTAGTCATGACAATAAAAAAATTATTTGTCCTCCAGT
TTGTAACCAAATGGCTTGCAATATGGGAATTCTTACTTGTTCAGAAACTG
GTTTGTCTGAAATTCCGAAGCTAATTCCTCCAAAAACAAATAAAATCTTG
TTGATCAATCAAGATTTTTCCGAAGCGGGAACTTTGACTCGATTAAATCT
CAGCGATTATAGTTCAAAGAAACATAAAATCACGAAAATTACAATTCAGA
ATTGTTCTTTACAAGCTATAGAATCAAGAGCCTTTTCACAAATAATTTAC
CTCGAAACTTTGGATCTTTCGTTTAACAAATTGACAGAACTTGAACCTTT
TACCTTTGCCGATTTGAATTTGAAATTTCTTCGACTAGATGGCAACTTGA
ATTTAAAATTAACCGCAAACTCATTTAAAGAACTCCGAGTTGATTCTTTA
TCACTCCTTGGTTGCCATTTGAGCCATTTGCCTTTTACTGTCTTGGAGCC
GATTTCCACAGGTCTTATCCAATTGATTCTAACAAGCAATCGGTTCACGA
CTCTTGAATCAAGATATGAAACATTATTTCAGCGGCTTTCTCGTTTCGGT
TTAGACGATAATCGTTTTGACTGCAGTCAGTGTTCACTGATCTGGATGGC
AAACACCATGAAAGCTATATATTATAAAAATCAAAACAAAGACCAACAAA
CGATTATTTATCCCAAATGTCATCAACCGTACAAACTAAAGGATAAGTTT
ATTCACAGCCTATCAAGTTCAGATTTTCAATGTCCGAAACCTTCGATAGA
GAAGATCAGCATTTTTATTCTCCCAAACAATACTGCACAATTGATTTGCA
CCGCCTCAGATGTGCAATCAAGTGTTATTTGGAGTCAAGTTTTTGAACCA
AATGATAAAGATTTTCTGTTGATCGAGCAGCGAAAACAAATTTTATCTAA
TTCGGCTCATTCAAACAAACTAGTGATCAATAAAAACCAAGATATCGACG
TGTTTTTGTGCACCGTAACCAGTTTAATTGGAAATGCTTCTAGTACGAGG
TTGCAAATTTCTTGGCCGAAATACAAAACTCAATTCCGTCTTTTGAACAA
TAGCCATAGAAATGTTTGGAATGATCCTTTGACTCCAATGCCCGGAGAAA
AATATCCGAAGAACTACTTTTTCCAACCGCAATTCTCCTTGATAGAAATG
ATATCTGGAGTAGTTGGAACCTTTATTGCTACGTTGATTGTGTTTATTAC
AATGTTGCGTTGTATTTTCTATCGAATAAGACTATTTTCAAAGAATTCCC
AACTTCGAGATCATCAATTGAGTTTGACAAGTTCGAAAAAAGACAAACGA
AAACAATATATGACATATGAGCCTCCGGTTTACTCTGATAGTCAAACTTA
TGACATTCCAACCCTGCCTGTGAACCAATCCACTCTAGGTCATTTCATTG
ACTTCAAAACTCAACAAACATTATATAGTGAAAAAAATCAGTGATAACAA
ATAAAAATCAAAAAAAAGGCACTTACTAAAAAAAGAATTATCATCTGTAG
TTTGAAACATTTATATTTAAAATAATACAAACAATTATTGAGTTTTCCAA
CAACGAATTTGATTGTTTATTTTTAATAGTAAATTTTGTTTATTAAAAAA
CAAAATTTGTTTACAGTATTTTCAGTTTCGACAACTATTTCGTCGGAGGA
TTGATGAAAAATTAAAATATTTTTTAGCATATCACAAAAAAGTTGTAAAA
AATATCTCGTGTAAATTATGTTTTCAAGTAAAATCGCGTTTTAATATTTA
TTTATTTTCGTCAATTGAATAATTCGTGCGCATAGTAATGTGTTGATGTA
AACTTATATTTTTTATACAATACGTAAGCACGTGTCTGATAGTAGCGTTG
TTTTGTTTACTTGATAAATGACAGTCAGTAACCCTGTCAAAGTCATGACC
GTTGTATACATTTCTGTGATTAGTTTACTGCGTACTTTGACAGGTTAGGA
CGACAGAATAAAGTTTTATTTTTTTATTAAT

protein sequence of SMED30017278-orf-1

>SMED30017278-orf-1 ID=SMED30017278-orf-1|Name=SMED30017278-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=529bp
MPINYEMLNLLTLSKTFLFYAQWILLSTTSSANIDFSHDNKKIICPPVCN
QMACNMGILTCSETGLSEIPKLIPPKTNKILLINQDFSEAGTLTRLNLSD
YSSKKHKITKITIQNCSLQAIESRAFSQIIYLETLDLSFNKLTELEPFTF
ADLNLKFLRLDGNLNLKLTANSFKELRVDSLSLLGCHLSHLPFTVLEPIS
TGLIQLILTSNRFTTLESRYETLFQRLSRFGLDDNRFDCSQCSLIWMANT
MKAIYYKNQNKDQQTIIYPKCHQPYKLKDKFIHSLSSSDFQCPKPSIEKI
SIFILPNNTAQLICTASDVQSSVIWSQVFEPNDKDFLLIEQRKQILSNSA
HSNKLVINKNQDIDVFLCTVTSLIGNASSTRLQISWPKYKTQFRLLNNSH
RNVWNDPLTPMPGEKYPKNYFFQPQFSLIEMISGVVGTFIATLIVFITML
RCIFYRIRLFSKNSQLRDHQLSLTSSKKDKRKQYMTYEPPVYSDSQTYDI
PTLPVNQSTLGHFIDFKTQQTLYSEKNQ*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000099	neuron
PLANA:0000418	head

Vocabulary: **INTERPRO**
Term	Definition
IPR036179	Ig-like_dom_sf
IPR032675	LRR_dom_sf
IPR001611	Leu-rich_rpt
IPR007110	Ig-like_dom

Vocabulary: **molecular function**
Term	Definition
GO:0005515	protein binding

Vocabulary: **cellular component**
Term	Definition
GO:0016020	membrane
GO:0016021	integral component of membrane

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR001611	Leucine-rich repeat	PFAM	PF13855	LRR_8	coord: 108..163 e-value: 3.1E-10 score: 39.7
IPR001611	Leucine-rich repeat	PROSITE	PS51450	LRR	coord: 131..152 score: 8.089
IPR001611	Leucine-rich repeat	PROSITE	PS51450	LRR	coord: 202..223 score: 4.778
IPR001611	Leucine-rich repeat	PROSITE	PS51450	LRR	coord: 154..175 score: 4.793
IPR032675	Leucine-rich repeat domain superfamily	GENE3D	G3DSA:3.80.10.10		coord: 42..167 e-value: 1.9E-15 score: 58.4
IPR032675	Leucine-rich repeat domain superfamily	GENE3D	G3DSA:3.80.10.10		coord: 168..294 e-value: 2.8E-12 score: 48.4
None	No IPR available	PANTHER	PTHR45842	FAMILY NOT NAMED	coord: 29..378
None	No IPR available	SUPERFAMILY	SSF52058	L domain-like	coord: 53..296
None	No IPR available	TMHMM	TMhelix		coord: 432..454
IPR007110	Immunoglobulin-like domain	PROSITE	PS50835	IG_LIKE	coord: 295..385 score: 7.94
IPR036179	Immunoglobulin-like domain superfamily	SUPERFAMILY	SSF48726	Immunoglobulin	coord: 293..380

Main menu

Ig-like domain-containing protein

Zeng et. al., 2018

▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 6

Owlery

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