DNA replication and sister chromatid cohesion 1

Overview


Name	DNA replication and sister chromatid cohesion 1
Smed ID	SMED30017245
Length (bp)	1226

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of DNA replication and sister chromatid cohesion 1 (SMED30017245) t-SNE clustered cells

Violin plots show distribution of expression levels for DNA replication and sister chromatid cohesion 1 (SMED30017245) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of DNA replication and sister chromatid cohesion 1 (SMED30017245) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30017245

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 6

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
X1 cell	SMED30017245	h1SMcG0003114	SmedASXL_009294	SmedAsxl_ww_GCZZ01	PMID:26114597 Zhu et al., 2015
X1 cell	SMED30017245	h1SMcG0003114	SmedASXL_009295	SmedAsxl_ww_GCZZ01	PMID:26114597 Zhu et al., 2015
parapharyngeal region	SMED30017245	h1SMcG0003114	dd_Smed_v6_17862_0_1	dd_Smed_v6	PMID:28171748 Stückemann et al., 2017
zeta neoblast	SMED30017245	h1SMcG0003114	dd_Smed_v4_17862_0_1	dd_Smed_v4	PMID:28292427 Wurtzel et al., 2017
neoblast	SMED30017245	h1SMcG0003114	SMED_31095_V2_1	GPL14150_gene_models	PMID:22385657 Wagner et al., 2012
neoblast	SMED30017245	h1SMcG0003114	SMED_31095_V2_1	GPL14150	PMID:22385657 Wagner et al., 2012

Note: Hover over icons to view figure legend

Homology

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BLAST of DNA replication and sister chromatid cohesion 1 vs. Ensembl Human
Match: DSCC1 (DNA replication and sister chromatid cohesion 1 [Source:HGNC Symbol;Acc:HGNC:24453])

HSP 1 Score: 93.2041 bits (230), Expect = 3.359e-20
Identity = 60/236 (25.42%), Postives = 118/236 (50.00%), Query Frame = 2

Query:  494 DENTNEEIYTFEKLLEVVIMSEEELKNALRELKVYNVDGHLRLLXXXXXXXXXXXXXECSFENDFSIFDVSQNNVQFMLNDLFPIEILDQTLNYYFVKLIEKDGDTIWKINIIEVTRCFAEFILNKSDEMKLEEFLVMWNEKLPEDLNGDINNLHGLVIINETSQPNSVKLVKFLTLSDEPEERFKELFLQKSHWQQEDLEGYIKDLVPPGMSASQLIMRFCRCINNAKIKTFSKR 1201
            ++++N   YT E LL+ +  SEEE+   L+ L    + G+ R+L  DY   ++  + +      +S   V  N     L  L P E+++  L  Y  K ++ +G+  ++++  ++ R  A  +L  + +  L EF  +W + +PE +   ++ L GL +++  S+P  + L+K   L ++ +ERF  LF  +  W +ED+  YI+DL     +   L+ ++        +K ++ R
Sbjct:  155 EKDSNSSKYTTEDLLDQIQASEEEIMTQLQVLNACKIGGYWRILEFDYEMKLLNHVTQLVDSESWSFGKVPLNTCLQELGPLEPEEMIEHCLKCYGKKYVD-EGEVYFELDADKICRAAARMLLQNAVKFNLAEFQEVWQQSVPEGMVTSLDQLKGLALVDRHSRPEIIFLLKVDDLPEDNQERFNSLFSLREKWTEEDIAPYIQDLCGEKQTIGALLTKYSHSSMQNGVKVYNSR 389

[Close]

BLAST of DNA replication and sister chromatid cohesion 1 vs. Ensembl Fly
Match: CG11788 (gene:FBgn0034495 transcript:FBtr0086277)

HSP 1 Score: 80.8777 bits (198), Expect = 2.453e-16
Identity = 60/227 (26.43%), Postives = 111/227 (48.90%), Query Frame = 2

Query:  515 IYTFEKLLEVVIMSEEELKNALRELKVYNVDGHLRLLXXXXXXXXXXXXXECSFENDFSIFDVSQNNVQFMLNDLFPIEILDQTLNYYFVKLIEKDGDTIWKINIIEVTRCFAEFILNKSDEMKLEEFLVMWNEKLPEDLNGDINNLHGLVIIN-ETSQPNSVKLVKFLTLSDEPEERFKELFLQKSHWQQEDLEGYIKDLVPPGMSASQLIMRFCRCINNAKIKTF 1192
            ++TF +LL+ V  S  +    L + +   +DG +R++  +Y Y II  ++    EN +++ +V +      L  + P +++    + Y +      G   ++ ++  V+R  A+ IL      + EEF+  W E LPE ++ D+  L GL I + E +QP    L + L L     +R + LF  K  W  E++E YI+    P +S S L+ +  R + +  ++ F
Sbjct:  198 LFTFSQLLDTVQCSRGQFMEGLNQYRAIELDGRMRVMEYEYEYRIINMMLGLISENSWALDEVEREETINALKGIAPEDVVAGLFDIYTIPSERCPGKFEYQESL--VSRIVAQNILQPGLRFRNEEFMRTWQEVLPEGMSCDLKYLRGLGICDKEGAQPCIRSLAEEL-LPTNISDRMRALFKTKKRWTMEEMEPYIECFTTPNLSVSTLLAKHARSLTDGGVRYF 421

[Close]

BLAST of DNA replication and sister chromatid cohesion 1 vs. Ensembl Zebrafish
Match: dscc1 (DNA replication and sister chromatid cohesion 1 [Source:NCBI gene;Acc:447872])

HSP 1 Score: 97.8265 bits (242), Expect = 5.468e-22
Identity = 60/228 (26.32%), Postives = 114/228 (50.00%), Query Frame = 2

Query:  518 YTFEKLLEVVIMSEEELKNALRELKVYNVDGHLRLLXXXXXXXXXXXXXECSFENDFSIFDVSQNNVQFMLNDLFPIEILDQTLNYYFVKLIEKDGDTIWKINIIEVTRCFAEFILNKSDEMKLEEFLVMWNEKLPEDLNGDINNLHGLVIINETSQPNSVKLVKFLTLSDEPEERFKELFLQKSHWQQEDLEGYIKDLVPPGMSASQLIMRFCRCINNAKIKTFSKR 1201
            Y+ E LLE +  S+EEL+  L  +    +DG  R++  DY   ++  + +      +S   V  +     L  L P  +++  LN Y  +  ++D   ++ ++  +V R  A+ +L  + +  L EF  +W + +PE +   ++ L GL +I+ +S+P ++ L++   L ++  ERF  LF  +  W Q+D+E YI+DL     +   L+ +  R      IK ++ R
Sbjct:  159 YSMEDLLERIQASKEELEAHLGNVHACEIDGFWRIMDFDYEMKLLGHVTQLVDSESWSFSKVPLSVCLEELGSLEPKAMIEHCLNCYGRRHSDEDNQVMYALDEDKVCRATAQLLLQNAVKFNLSEFQEVWQQSVPEGMGTRLDQLRGLALIDRSSKPETISLLRVEDLPEDTLERFNSLFSLREKWTQDDIEPYIQDLCGEKQTTGALLTKHARSSMQNGIKVYNSR 386

[Close]

BLAST of DNA replication and sister chromatid cohesion 1 vs. Ensembl Xenopus
Match: dscc1 (DNA replication and sister chromatid cohesion 1 [Source:NCBI gene;Acc:448100])

HSP 1 Score: 94.7449 bits (234), Expect = 8.224e-21
Identity = 65/236 (27.54%), Postives = 118/236 (50.00%), Query Frame = 2

Query:  497 ENTNEEIYTFEKLLEVVIMSEEELKNALRELKVYNVDGHLRLLXXXXXXXXXXXXXECSFENDFSIFDVSQNNVQFMLNDLFPIEILDQTLNYYFVKLI-EKDGDTIWKINIIEVTRCFAEFILNKSDEMKLEEFLVMWNEKLPEDLNGDINNLHGLVIINETSQPNSVKLVKFLTLSDEPEERFKELFLQKSHWQQEDLEGYIKDLVPPGMSASQLIMRFCRCINNAKIKTFSKR 1201
            E+ +  ++T E LL ++  S EEL + L+ +   +++G  RLL  DY   ++  I +      +S   V        L  L P E+++  L  Y  +LI E  G   + ++  ++ R  A  +L  + +  L EF  +W + +PE +N  ++ L GL +++ TS+P ++ L+K   L ++ +ERF  LF  +  W + D+  YIKDL     +   L+ ++ R      IK ++ R
Sbjct:  152 ESQDNSLHTTEDLLNMIQASNEELVDHLKAIHACSINGFWRLLDFDYEMKLLNHITQLIDSESWSFSKVPLPVCLQELRSLEPEEMIEHCLTCYGKRLIDEGTGGDFFALDEDKICRATALMLLQNAVKFNLAEFQEVWQQSVPEGMNTRLDQLKGLALVDRTSRPETIFLLKTEDLPEDTQERFNTLFGMREKWAEADIAPYIKDLCGEKQTIGALLTKYARSSMQNGIKLYNSR 387

[Close]

BLAST of DNA replication and sister chromatid cohesion 1 vs. Ensembl Mouse
Match: Dscc1 (DNA replication and sister chromatid cohesion 1 [Source:MGI Symbol;Acc:MGI:1919357])

HSP 1 Score: 92.0485 bits (227), Expect = 6.303e-20
Identity = 62/236 (26.27%), Postives = 117/236 (49.58%), Query Frame = 2

Query:  494 DENTNEEIYTFEKLLEVVIMSEEELKNALRELKVYNVDGHLRLLXXXXXXXXXXXXXECSFENDFSIFDVSQNNVQFMLNDLFPIEILDQTLNYYFVKLIEKDGDTIWKINIIEVTRCFAEFILNKSDEMKLEEFLVMWNEKLPEDLNGDINNLHGLVIINETSQPNSVKLVKFLTLSDEPEERFKELFLQKSHWQQEDLEGYIKDLVPPGMSASQLIMRFCRCINNAKIKTFSKR 1201
            +E+ +   YT E LL  +  SEEE+   L+ L    + G+ R+L  DY   ++  + +      +S+  V        L  L P E+++  L  Y  + ++KD D  ++++  ++ R  AE +L  + +  L EF  +W + +PE +   ++ L GL +++  S+P  + L+K   L +  ++RF  LF  +  W +ED+  YI+DL     +   L+ ++ R      IK ++ R
Sbjct:  161 EEDASRSKYTTEDLLNHIQASEEEIMAQLQVLNACEIGGYWRILEFDYEIKLLNHVTQLVDSESWSLDRVPLTVCLQELGPLEPEEMIEHCLKCYGKRYVDKD-DVYFELDADKICRVTAEMLLQNAVKFNLAEFQEVWQQSVPEGMTTRLDQLKGLALVDRNSRPEIIFLLKVDDLPEGTQDRFNSLFSLREKWTEEDITPYIQDLCGEKQTIGALLTKYSRSSMQNGIKVYNSR 395

[Close]

BLAST of DNA replication and sister chromatid cohesion 1 vs. Ensembl Mouse
Match: Dscc1 (DNA replication and sister chromatid cohesion 1 [Source:MGI Symbol;Acc:MGI:1919357])

HSP 1 Score: 77.411 bits (189), Expect = 6.551e-15
Identity = 40/151 (26.49%), Postives = 80/151 (52.98%), Query Frame = 2

Query:  749 EILDQTLNYYFVKLIEKDGDTIWKINIIEVTRCFAEFILNKSDEMKLEEFLVMWNEKLPEDLNGDINNLHGLVIINETSQPNSVKLVKFLTLSDEPEERFKELFLQKSHWQQEDLEGYIKDLVPPGMSASQLIMRFCRCINNAKIKTFSKR 1201
            E+++  L  Y  + ++KD D  ++++  ++ R  AE +L  + +  L EF  +W + +PE +   ++ L GL +++  S+P  + L+K   L +  ++RF  LF  +  W +ED+  YI+DL     +   L+ ++ R      IK ++ R
Sbjct:  309 EMIEHCLKCYGKRYVDKD-DVYFELDADKICRVTAEMLLQNAVKFNLAEFQEVWQQSVPEGMTTRLDQLKGLALVDRNSRPEIIFLLKVDDLPEGTQDRFNSLFSLREKWTEEDITPYIQDLCGEKQTIGALLTKYSRSSMQNGIKVYNSR 458

[Close]

BLAST of DNA replication and sister chromatid cohesion 1 vs. UniProt/SwissProt
Match: sp|Q66I84|DCC1_DANRE (Sister chromatid cohesion protein DCC1 OS=Danio rerio OX=7955 GN=dscc1 PE=2 SV=1)

HSP 1 Score: 98.5969 bits (244), Expect = 2.111e-21
Identity = 61/228 (26.75%), Postives = 114/228 (50.00%), Query Frame = 2

Query:  518 YTFEKLLEVVIMSEEELKNALRELKVYNVDGHLRLLXXXXXXXXXXXXXECSFENDFSIFDVSQNNVQFMLNDLFPIEILDQTLNYYFVKLIEKDGDTIWKINIIEVTRCFAEFILNKSDEMKLEEFLVMWNEKLPEDLNGDINNLHGLVIINETSQPNSVKLVKFLTLSDEPEERFKELFLQKSHWQQEDLEGYIKDLVPPGMSASQLIMRFCRCINNAKIKTFSKR 1201
            Y+ E LLE +  S+EEL+  L  +    +DG  R+L  DY   ++  + +      +S   V  +     L  L P  +++  LN Y  +  ++D   ++ ++  +V R  A+ +L  + +  L EF  +W + +PE +   ++ L GL +I+ +S+P ++ L++   L ++  ERF  LF  +  W Q+D+E YI+DL     +   L+ +  R      IK ++ R
Sbjct:  159 YSMEDLLERIQASKEELEAHLGNVHACEIDGFWRILDFDYEMKLLGHVTQLVDSESWSFSKVPLSVCLEELGSLEPKAMIEHCLNCYGRRHSDEDNQVMYALDEDKVCRATAQLLLQNAVKFNLSEFQEVWQQSVPEGMGTRLDQLRGLALIDRSSKPETISLLRVEDLPEDTLERFNSLFSLREKWTQDDIEPYIQDLCGEKQTTGALLTKHARSSMQNGIKVYNSR 386

[Close]

BLAST of DNA replication and sister chromatid cohesion 1 vs. UniProt/SwissProt
Match: sp|Q6GMB0|DCC1_XENLA (Sister chromatid cohesion protein DCC1 OS=Xenopus laevis OX=8355 GN=dscc1 PE=2 SV=1)

HSP 1 Score: 97.4413 bits (241), Expect = 5.823e-21
Identity = 65/229 (28.38%), Postives = 116/229 (50.66%), Query Frame = 2

Query:  515 IYTFEKLLEVVIMSEEELKNALRELKVYNVDGHLRLLXXXXXXXXXXXXXECSFENDFSIFDVSQNNVQFMLNDLFPIEILDQTLNYYFVKLIEKDGDTIWKINIIEVTRCFAEFILNKSDEMKLEEFLVMWNEKLPEDLNGDINNLHGLVIINETSQPNSVKLVKFLTLSDEPEERFKELFLQKSHWQQEDLEGYIKDLVPPGMSASQLIMRFCRCINNAKIKTFSKR 1201
            +YT E LL V+  S EEL + L+ +   N+ G  RLL  DY   ++  I +      +S   V        L  L P E+++  L  Y  +L+E+ GD  + ++  ++ R  A  +L  + +  L EF  +W + +P+ +N  ++ L GL +++ TS+P ++ L++   L ++ +ERF  LF  +  W + D+  YI+DL     +   L+ ++ R      IK F+ R
Sbjct:  159 LYTTEDLLSVIQSSTEELMDHLKAIHACNIKGIWRLLDFDYEMKLLNHITQLIDSESWSFSKVPLQVCLQELRSLEPEEMIEHCLTCYGKRLMEEGGD-CFALDEDKICRATALMLLQNAVKFNLAEFQEVWQQSVPDGMNTRLDQLKGLALVDRTSRPETIFLLQTEDLPEDTQERFNTLFGMREKWTEADIAPYIQDLCGEKQTIGALLTKYARSSMQNGIKLFNSR 386

[Close]

BLAST of DNA replication and sister chromatid cohesion 1 vs. UniProt/SwissProt
Match: sp|Q6GL75|DCC1_XENTR (Sister chromatid cohesion protein DCC1 OS=Xenopus tropicalis OX=8364 GN=dscc1 PE=2 SV=1)

HSP 1 Score: 94.7449 bits (234), Expect = 4.357e-20
Identity = 65/236 (27.54%), Postives = 118/236 (50.00%), Query Frame = 2

Query:  497 ENTNEEIYTFEKLLEVVIMSEEELKNALRELKVYNVDGHLRLLXXXXXXXXXXXXXECSFENDFSIFDVSQNNVQFMLNDLFPIEILDQTLNYYFVKLI-EKDGDTIWKINIIEVTRCFAEFILNKSDEMKLEEFLVMWNEKLPEDLNGDINNLHGLVIINETSQPNSVKLVKFLTLSDEPEERFKELFLQKSHWQQEDLEGYIKDLVPPGMSASQLIMRFCRCINNAKIKTFSKR 1201
            E+ +  ++T E LL ++  S EEL + L+ +   +++G  RLL  DY   ++  I +      +S   V        L  L P E+++  L  Y  +LI E  G   + ++  ++ R  A  +L  + +  L EF  +W + +PE +N  ++ L GL +++ TS+P ++ L+K   L ++ +ERF  LF  +  W + D+  YIKDL     +   L+ ++ R      IK ++ R
Sbjct:  152 ESQDNSLHTTEDLLNMIQASNEELVDHLKAIHACSINGFWRLLDFDYEMKLLNHITQLIDSESWSFSKVPLPVCLQELRSLEPEEMIEHCLTCYGKRLIDEGTGGDFFALDEDKICRATALMLLQNAVKFNLAEFQEVWQQSVPEGMNTRLDQLKGLALVDRTSRPETIFLLKTEDLPEDTQERFNTLFGMREKWAEADIAPYIKDLCGEKQTIGALLTKYARSSMQNGIKLYNSR 387

[Close]

BLAST of DNA replication and sister chromatid cohesion 1 vs. UniProt/SwissProt
Match: sp|Q9BVC3|DCC1_HUMAN (Sister chromatid cohesion protein DCC1 OS=Homo sapiens OX=9606 GN=DSCC1 PE=1 SV=2)

HSP 1 Score: 93.2041 bits (230), Expect = 1.613e-19
Identity = 60/236 (25.42%), Postives = 118/236 (50.00%), Query Frame = 2

Query:  494 DENTNEEIYTFEKLLEVVIMSEEELKNALRELKVYNVDGHLRLLXXXXXXXXXXXXXECSFENDFSIFDVSQNNVQFMLNDLFPIEILDQTLNYYFVKLIEKDGDTIWKINIIEVTRCFAEFILNKSDEMKLEEFLVMWNEKLPEDLNGDINNLHGLVIINETSQPNSVKLVKFLTLSDEPEERFKELFLQKSHWQQEDLEGYIKDLVPPGMSASQLIMRFCRCINNAKIKTFSKR 1201
            ++++N   YT E LL+ +  SEEE+   L+ L    + G+ R+L  DY   ++  + +      +S   V  N     L  L P E+++  L  Y  K ++ +G+  ++++  ++ R  A  +L  + +  L EF  +W + +PE +   ++ L GL +++  S+P  + L+K   L ++ +ERF  LF  +  W +ED+  YI+DL     +   L+ ++        +K ++ R
Sbjct:  155 EKDSNSSKYTTEDLLDQIQASEEEIMTQLQVLNACKIGGYWRILEFDYEMKLLNHVTQLVDSESWSFGKVPLNTCLQELGPLEPEEMIEHCLKCYGKKYVD-EGEVYFELDADKICRAAARMLLQNAVKFNLAEFQEVWQQSVPEGMVTSLDQLKGLALVDRHSRPEIIFLLKVDDLPEDNQERFNSLFSLREKWTEEDIAPYIQDLCGEKQTIGALLTKYSHSSMQNGVKVYNSR 389

[Close]

BLAST of DNA replication and sister chromatid cohesion 1 vs. UniProt/SwissProt
Match: sp|Q14AI0|DCC1_MOUSE (Sister chromatid cohesion protein DCC1 OS=Mus musculus OX=10090 GN=DSCC1 PE=2 SV=1)

HSP 1 Score: 92.0485 bits (227), Expect = 4.409e-19
Identity = 62/236 (26.27%), Postives = 117/236 (49.58%), Query Frame = 2

Query:  494 DENTNEEIYTFEKLLEVVIMSEEELKNALRELKVYNVDGHLRLLXXXXXXXXXXXXXECSFENDFSIFDVSQNNVQFMLNDLFPIEILDQTLNYYFVKLIEKDGDTIWKINIIEVTRCFAEFILNKSDEMKLEEFLVMWNEKLPEDLNGDINNLHGLVIINETSQPNSVKLVKFLTLSDEPEERFKELFLQKSHWQQEDLEGYIKDLVPPGMSASQLIMRFCRCINNAKIKTFSKR 1201
            +E+ +   YT E LL  +  SEEE+   L+ L    + G+ R+L  DY   ++  + +      +S+  V        L  L P E+++  L  Y  + ++KD D  ++++  ++ R  AE +L  + +  L EF  +W + +PE +   ++ L GL +++  S+P  + L+K   L +  ++RF  LF  +  W +ED+  YI+DL     +   L+ ++ R      IK ++ R
Sbjct:  161 EEDASRSKYTTEDLLNHIQASEEEIMAQLQVLNACEIGGYWRILEFDYEIKLLNHVTQLVDSESWSLDRVPLTVCLQELGPLEPEEMIEHCLKCYGKRYVDKD-DVYFELDADKICRVTAEMLLQNAVKFNLAEFQEVWQQSVPEGMTTRLDQLKGLALVDRNSRPEIIFLLKVDDLPEGTQDRFNSLFSLREKWTEEDITPYIQDLCGEKQTIGALLTKYSRSSMQNGIKVYNSR 395

[Close]

BLAST of DNA replication and sister chromatid cohesion 1 vs. TrEMBL
Match: T1FMB4 (Uncharacterized protein OS=Helobdella robusta OX=6412 GN=20209963 PE=4 SV=1)

HSP 1 Score: 105.531 bits (262), Expect = 2.331e-31
Identity = 67/263 (25.48%), Postives = 132/263 (50.19%), Query Frame = 2

Query:  413 FYEVNLRKSKIGQVYKILQRSILYHHIDENTNEEIYTFEKLLEVVIMSEEELKNALRELKVYNVDGHLRLLXXXXXXXXXXXXXECSFENDFSIFDVSQNNVQFMLNDLFPIEILDQTLNYYFVKLIEKDGDTIWKINIIEVTRCFAEFILNKSDEMKLEEFLVMWNEKLPEDLNGDINNLHGLVIINETSQPNSVKLVKFLTLSDEPEERFKELFLQKSHWQQEDLEGYIKDLVPPGMSASQLIMRFCRCINNAKIKTFSKR 1201
            +YE+  R++++ ++ + L     Y   D + ++ +Y+FE LL+ V  S +EL++ L+ L    + G+ RLL  +Y+  +   ++    EN +S   +    ++  L +L+  EI D  +  +    IE DG     +N ++  R +AE IL  + +  L EF   W   +P+ +  D+N L  L +I+  S+P  ++      L ++ + RF+ LF  K  W  E++  Y++D      +   L+M++ R   +  +K +S +
Sbjct:  131 YYELKARRARLKRLKEKLDEHP-YSACDTDQHD-LYSFEDLLDEVQTSHKELEDGLKSLHACQIGGYWRLLDFEYLCSLFRSVLAIVDENGWSYHCIPSRQLEQALMELYKREITDHVMGLF---TIEHDGKETCSLNELDTCRLYAEMILKTTAKFNLVEFCETWQLSVPDGMVTDLNQLKNLAVIDRDSKPEVIRYFPACDLPEDLQARFQVLFKTKEKWTFEEITPYLEDSCTGNTNVGNLLMKYARLSTSRGVKVYSSK 388

HSP 2 Score: 60.4622 bits (145), Expect = 2.331e-31
Identity = 36/85 (42.35%), Postives = 54/85 (63.53%), Query Frame = 3

Query:   72 DILNLIKCSPESFSKISQTIVFGEDFAKEGCYIFKXXXXXXXXXXXXXQPNSFVIKGKTNDIAVLCTNNKSYEIREAETSNALLI 326
            ++LN  K          Q+  FGE+   E  Y+F+I+  +LE L S+    SFVI+G  ND AVLCT +K++++RE+ETSN+LL+
Sbjct:   16 ELLNFAKIDKNYMKNYVQSFYFGENLHHEDVYLFEIDKSLLEDLKSS---RSFVIRGGANDTAVLCTESKTFDLRESETSNSLLL 97

[Close]

BLAST of DNA replication and sister chromatid cohesion 1 vs. TrEMBL
Match: D6WSW4 (Sister chromatid cohesion protein DCC1-like Protein OS=Tribolium castaneum OX=7070 GN=TcasGA2_TC030592 PE=4 SV=2)

HSP 1 Score: 112.849 bits (281), Expect = 1.582e-28
Identity = 75/283 (26.50%), Postives = 144/283 (50.88%), Query Frame = 2

Query:  359 RKRAFINQLITVSSTCNKFYEVNLRKSKIGQVYKILQRSILY--HHIDENTNEEIYTFEKLLEVVIMSEEELKNALRELKVYNVDGHLRLLXXXXXXXXXXXXXECSFENDFSIFDVSQNNVQFMLNDLFPIEILDQTLNYYFVKLIEKDGDTIWKINIIEVTRCFAEFILNKSDEMKLEEFLVMWNEKLPEDLNGDINNLHGLVIINETSQPNSVKLVKFLTLSDEPEERFKELFLQKSHWQQEDLEGYIKDLVPPGMSASQLIMRFCRCINNAKIKTFSKR 1201
            ++RA   Q +TVS     +  V   K  + ++  +L +S+     H  E  NE++Y ++ L++++  S++EL++ L+++ V  ++G +RLL ++Y +  +  +++   EN +++ ++  +     L D+ P  IL    + Y  +    DG  ++     E+ R FA+ +L  + +  LEEFL  W E +PE +  D   LHG+ II+  S P  +       L +E   RF +LF  K  W   ++  YI+ +    M  + L+ +F R  N+  +K +S +
Sbjct:  110 KERAL--QTVTVSGVFYDYLSVTPGKPHLKKLRDLLDKSVYKGPEHEYEIKNEDLYGYDDLIKIIQASDQELESVLKQMNVVTINGKIRLLDVEYHFRALSYMLKLIEENSWNLDEIDFDETLNSLRDIIPETILKNLFDKYTTESKIVDGLQLYSYKEREICRFFAQILLYGAGKFNLEEFLQAWRESVPEGMTCDEELLHGIAIIDRKSDPPVISAFPEEELPEEINARFNKLFKAKEKWTVPEITPYIQRVATDKMDVNALLAKFARASNSQGVKFYSAK 390

HSP 2 Score: 43.8986 bits (102), Expect = 1.582e-28
Identity = 30/93 (32.26%), Postives = 45/93 (48.39%), Query Frame = 3

Query:   57 TQNCEDI---LNLIKCSPESFSKISQTIVFGEDFAKEGCYIFKXXXXXXXXXXXXXQPNSFVIKGKTNDIAVLCTNNKSYEIREAETSNALLI 326
            T++ +D+   L L K         SQT+ F  D     C  FK        L    Q  +  IKG  ++  VLCT +++Y++  AETSN+LL+
Sbjct:    6 TRDLDDVNEMLKLAKLGENDVLSTSQTVYFTSD--NLNCDNFKFLELDQHLLEEIKQGQTLYIKGDDDENVVLCTKDRTYDVTGAETSNSLLL 96

[Close]

BLAST of DNA replication and sister chromatid cohesion 1 vs. TrEMBL
Match: A0A023F1I3 (Uncharacterized protein (Fragment) OS=Triatoma infestans OX=30076 PE=2 SV=1)

HSP 1 Score: 92.4337 bits (228), Expect = 6.484e-28
Identity = 67/270 (24.81%), Postives = 132/270 (48.89%), Query Frame = 2

Query:  413 FYEVNLRKSKIGQVYKIL-QRSILYHHIDE-NTNEEIYTFEKLLEVVIMSEEELKNALRELKVYNVDGHLRLLXXXXXXXXXXXXXECSFENDFSIFDVSQNNVQFMLNDLFPIEILDQTLNYYFVKLIE--KDGDTIWKINIIEVTRCFAEFILNKSDEMKLEEFLVMWNEKLPEDLNGDINNLHGLVIINETSQPNSVKLVKFLTLSDEP---EERFKELFLQKSHWQQEDLEGYIKDLVPPGMSASQLIMRFCRCINNAKIKTFSKR 1201
            +YE+   K ++ ++  +L +R      ++E + ++  Y+ + L+E +  SEEE+K  L ++   ++ G  RLL   Y +  +  ++    EN + + ++       +LN+L P EI    +  Y     E    GDT+ +I   +  R    ++L ++ +  L++FL  W + +PE L  ++  L GL +    ++P   +L+ +    D P   +ERF  LF Q+  W   ++E YI++L     S+  ++ +F R  +    K +S R
Sbjct:  121 YYELKKIKPRLSRIRHLLNERQYKGSELEEQDQSDGYYSIDDLIERIQASEEEIKQGLSDIDAVSIKGKWRLLEDQYHFRALSFMLNLLDENSWKVNEIPLGETLEILNELLPKEIASHIVEMYLEPTGEFNDAGDTLMQIKEDKTCRYLGGYLLRQAAKFSLKDFLEAWQQSVPEGLTTNLKQLAGLALYTLETKP---QLIWYFPEEDLPVDLQERFSVLFKQREKWNFNEIEPYIRNLSSEKQSSHAILTKFARVSHINGTKYYSSR 387

HSP 2 Score: 62.003 bits (149), Expect = 6.484e-28
Identity = 35/91 (38.46%), Postives = 53/91 (58.24%), Query Frame = 3

Query:   54 STQNCEDILNLIKCSPESFSKISQTIVFGEDFAKEGCYIFKXXXXXXXXXXXXXQPNSFVIKGKTNDIAVLCTNNKSYEIREAETSNALLI 326
            + ++ E ++   K        ISQ I FG+ F K     +K+     + L S  + +  + KG+ ND AVLCTNNK+YE++EAETSN+LL+
Sbjct:    5 TVEDVETVIGHAKLDVSELRPISQVIYFGKKFEK-----YKLLELDADVLESLKKGDRVMFKGEANDKAVLCTNNKTYEVKEAETSNSLLL 90

[Close]

BLAST of DNA replication and sister chromatid cohesion 1 vs. TrEMBL
Match: A0A067REG9 (Sister chromatid cohesion protein DCC1 OS=Zootermopsis nevadensis OX=136037 GN=L798_02371 PE=4 SV=1)

HSP 1 Score: 106.301 bits (264), Expect = 9.467e-28
Identity = 70/274 (25.55%), Postives = 149/274 (54.38%), Query Frame = 2

Query:  407 NKFYEVNLRKSKIGQVYKILQRSIL----YHHIDENTNEEIYTFEKLLEVVIMSEEELKNALRELKVYNVDGHLRLLXXXXXXXXXXXXXECSFENDFSIFDVSQNNVQFMLNDLFPIEILDQTLNYYFVKLI--EKDGDTIWKINIIEVTRCFAEFILNKSDEMKLEEFLVMWNEKLPEDLNGDINNLHGLVIINETSQPNSVKLVKFLTLSDEPE---ERFKELFLQKSHWQQEDLEGYIKDLVPPGMSASQLIMRFCRCINNAKIKTFSKR 1201
            +K+YE+ + K K+ +V+++L++ +     Y      T  ++YTF+ LL+ V  S+ ELK  L+E   + ++G  R L  +Y + ++  I+    EN + I  V++      L  L P++ILDQ  ++Y  + +   K+G+ ++++    V R  AE +L ++ +  LEEFL+ W + +PE +      L G+ ++++ S+P   +++ + + +D PE   ER + LF  +  W  +++  Y++ L    ++ + L+ ++ R  +   ++ +S +
Sbjct:  137 HKYYELRICKPKLRKVHQLLEKCLYRGPEYEDDIVKTGVKLYTFQDLLDNVQASKLELKAELKENMAFCINGAWRFLEHEYHFRVLSYILNFVDENSWPINQVNKTETLQSLAALVPMDILDQCFSWYAEETVAASKEGEPLYRLLEARVCRFLAEVLLRQAGKFNLEEFLLSWQQSVPEGMQTSEKYLEGMALMDKNSKP---EVIWYFSEADLPEDINERIRILFQTREKWTLDEIRPYVQRLATEKVNVNALLTKYARASSVGGVRYYSAK 407

HSP 2 Score: 47.3654 bits (111), Expect = 9.467e-28
Identity = 31/92 (33.70%), Postives = 51/92 (55.43%), Query Frame = 3

Query:   60 QNCEDILNLI---KCSPESFSKISQTIVFGEDFAKEGCYIFKXXXXXXXXXXXXXQPNSFVIKGKTNDIAVLCTNNKSYEIREAETSNALLI 326
            +  ED+ N+I   K S +    ++Q + F      +  Y F   +  L +   N Q  S V +G  ++ AVLCTN ++Y+++EAETSN+LL+
Sbjct:   19 RTVEDVQNVIQHAKLSDDELHPLTQVLSFAPKIEVQEKYKFLELDSTLLNNLQNGQ--SLVFRGTKDENAVLCTNKQTYDVKEAETSNSLLL 108

[Close]

BLAST of DNA replication and sister chromatid cohesion 1 vs. TrEMBL
Match: A0A1S3IFT1 (sister chromatid cohesion protein DCC1 isoform X2 OS=Lingula unguis OX=7574 GN=LOC106163620 PE=4 SV=1)

HSP 1 Score: 107.457 bits (267), Expect = 2.553e-27
Identity = 73/281 (25.98%), Postives = 139/281 (49.47%), Query Frame = 2

Query:  392 VSSTCNKFYEVNLRKSKIGQVYKILQRSILYH---HIDENTNEEIYTFEKLLEVVIMSEEELKNALRELKVYNVDGHLRLLXXXXXXXXXXXXXECSFENDFSIFDVSQNNVQFMLNDLFPIEILDQTLNYYFVKLIEKDG--------DTIWKINIIEVTRCFAEFILNKSDEMKLEEFLVMWNEKLPEDLNGDINNLHGLVIINETSQPNSVKLVKFLTLSDEPEERFKELFLQKSHWQQEDLEGYIKDLVPPGMSASQLIMRFCRCINNAKIKTFSKR 1201
            VS+    ++E+   K ++ ++ ++L+ ++        DEN +   Y++  L E+V  SE E++  L+ L+   +DG++R+L  DY+  ++  I     END++   +        L DL+   I+   L+ Y  K     G        D  + +   ++ R +AE +L  S++  L+EFL+ W E +P  +  D   L GL +I++TS+P  +       L ++ E RF  LF  +  W +E++  YIKD+    M    L+M++ R   +  +K ++ +
Sbjct:   79 VSAILYNYFELRPIKPRLKKMKELLEENVYSGPECEEDENHHGRKYSYADLKELVQASEGEIQEGLKALQAVEIDGYIRMLDFDYLQKVLSSIAGLVEENDWTTDHLPLRTCLEELQDLYDRHIIIHVLDCYGTKSDPGGGKNMEADSADVEYALCESKICRFYAEILLRASEKFNLQEFLLTWQESVPVGMKTDSCQLEGLALIDKTSRPEVIIYFPVEELPEDIEARFNALFRVREKWTKEEITPYIKDVATEKMGTGALLMKYARASTSNGVKVYNSK 359

HSP 2 Score: 44.669 bits (104), Expect = 2.553e-27
Identity = 19/35 (54.29%), Postives = 27/35 (77.14%), Query Frame = 3

Query:  222 NSFVIKGKTNDIAVLCTNNKSYEIREAETSNALLI 326
            +   I+G   D AV+CTN K++EI+EAETSN++LI
Sbjct:   24 DRLTIRGDKTDSAVVCTNRKTFEIKEAETSNSVLI 58

[Close]

BLAST of DNA replication and sister chromatid cohesion 1 vs. Ensembl Cavefish
Match: dscc1 (DNA replication and sister chromatid cohesion 1 [Source:NCBI gene;Acc:103022231])

HSP 1 Score: 94.3597 bits (233), Expect = 7.172e-21
Identity = 61/231 (26.41%), Postives = 113/231 (48.92%), Query Frame = 2

Query:  509 EEIYTFEKLLEVVIMSEEELKNALRELKVYNVDGHLRLLXXXXXXXXXXXXXECSFENDFSIFDVSQNNVQFMLNDLFPIEILDQTLNYYFVKLIEKDGDTIWKINIIEVTRCFAEFILNKSDEMKLEEFLVMWNEKLPEDLNGDINNLHGLVIINETSQPNSVKLVKFLTLSDEPEERFKELFLQKSHWQQEDLEGYIKDLVPPGMSASQLIMRFCRCINNAKIKTFSKR 1201
            E  YT + LL+ +  S EEL+  L  +    ++G  R+L  DY   ++  + +      +S   V   +    L  L P  +++  LN Y  +    +G+ ++ ++  +V R  A  +L  + +  L EF  +W + +P+ +   ++ L GL +++ +S+P +V L+K   L D+  ERF  LF  +  W Q+D+E YI+DL     +   L+ +  R      IK ++ R
Sbjct:  168 ESKYTMQDLLDRIQSSREELEAHLHTIHACEINGCWRILEFDYELKLLGHVTQLVDSESWSFSKVPLRSCLEELGPLEPTAMIEHCLNCYGRRYNTDEGEVMFALDEDKVCRAMALMLLQNAVKFNLSEFQEVWQQSVPDGMATRLDQLRGLALVDRSSRPETVFLLKVEDLPDDTLERFNALFSLREKWTQDDIEPYIQDLCGEKQTTGALLTKHARSSVQNGIKVYNSR 398

[Close]

BLAST of DNA replication and sister chromatid cohesion 1 vs. Ensembl Cavefish
Match: dscc1 (DNA replication and sister chromatid cohesion 1 [Source:NCBI gene;Acc:103022231])

HSP 1 Score: 84.3445 bits (207), Expect = 1.213e-17
Identity = 54/200 (27.00%), Postives = 101/200 (50.50%), Query Frame = 2

Query:  509 EEIYTFEKLLEVVIMSEEELKNALRELKVYNVDGHLRLLXXXXXXXXXXXXXECSFENDFSIFDVSQNNVQFMLNDLFPIEILDQTLNYYFVKLIEKDGDTIWKINIIEVTRCFAEFILNKSDEMKLEEFLVMWNEKLPEDLNGDINNLHGLVIINETSQPNSVKLVKFLTLSDEPEERFKELFLQKSHWQQEDLEGYIK 1108
            E  YT + LL+ +  S EEL+  L  +    ++G  R+L  DY   ++  + +      +S   V   +    L  L P  +++  LN Y  +    +G+ ++ ++  +V R  A  +L  + +  L EF  +W + +P+ +   ++ L GL +++ +S+P +V L+K   L D+  ERF  LF  +  W Q+D+E YI+
Sbjct:  168 ESKYTMQDLLDRIQSSREELEAHLHTIHACEINGCWRILEFDYELKLLGHVTQLVDSESWSFSKVPLRSCLEELGPLEPTAMIEHCLNCYGRRYNTDEGEVMFALDEDKVCRAMALMLLQNAVKFNLSEFQEVWQQSVPDGMATRLDQLRGLALVDRSSRPETVFLLKVEDLPDDTLERFNALFSLREKWTQDDIEPYIQ 367

[Close]

BLAST of DNA replication and sister chromatid cohesion 1 vs. Ensembl Sea Lamprey
Match: dscc1 (DNA replication and sister chromatid cohesion 1 [Source:NCBI gene;Acc:447872])

HSP 1 Score: 102.834 bits (255), Expect = 6.989e-25
Identity = 67/270 (24.81%), Postives = 129/270 (47.78%), Query Frame = 2

Query:  407 NKFYEVNLRKSKIGQVYKILQRSILYHHIDENT--NEEIYTFEKLLEVVIMSEEELKNALRELKVYNVDGHLRLLXXXXXXXXXXXXXECSFENDFSIFDVSQNNVQFMLNDLFPIEILDQTLNYYFVKLIEKDG---DTIWKINIIEVTRCFAEFILNKSDEMKLEEFLVMWNEKLPEDLNGDINNLHGLVIINETSQPNSVKLVKFLTLSDEPEERFKELFLQKSHWQQEDLEGYIKDLVPPGMSASQLIMRFCRCINNAKIKTFSKR 1201
            N + EV   + ++ ++  +L         +E     ++ YT   LL+ V  SE EL+  L+ L    +DG  R+L +DY   ++  + +      +S   V        L  L P ++++  LN Y  +  E++G   + ++ ++   V R  A  +L    +  L EF  +W + +PE ++  +  L G+ ++   ++P  + L++   L D+P+ERF +LF  +  W +ED+  Y++DL     S S L+ +  R   +  +K F+ R
Sbjct:   66 NSYLEVRRCRPRLKKLRSLLGECPFSGPENEAQYEGQQKYTTADLLDRVQASEVELQAGLKALNACQIDGRWRMLDLDYEMRLLSLLTQLVDSESWSFRHVPLRVCLDELGVLEPRDMIEHCLNCYGERTDEEEGGAAEVVYSLHEDRVCRALAVMLLKGCVKFNLAEFCDVWRQSVPEGMDAQLGQLQGVALVERAARPEVISLLRVEDLPDDPQERFSKLFSLRDKWTEEDIAPYVRDLCAEKQSVSALLTKHARSSMHNGVKVFNSR 335

[Close]

BLAST of DNA replication and sister chromatid cohesion 1 vs. Ensembl Yeast
Match: DCC1 (Subunit of a complex with Ctf8p and Ctf18p; shares some components with Replication Factor C; required for sister chromatid cohesion and telomere length maintenance [Source:SGD;Acc:S000000521])

HSP 1 Score: 56.6102 bits (135), Expect = 2.245e-9
Identity = 42/143 (29.37%), Postives = 71/143 (49.65%), Query Frame = 2

Query:  749 EILDQTLNYYFVKLIEKDGDTIWKINIIEVTRCFAEFILNK---SDEMKLEEFLVMWNEKLPE--DLNGDINNLHGLVIINETSQPNSVKLVKFLTLSDEPEERFKELFLQKSHWQQEDLEGYIKDLVPPGMSASQLIMRFCR 1162
            EI++  LN + V+  E + +T W++ I  + + +    L K      M ++EFL+ W    P     + DI+ L G    +      +V+ +   TL  +P+ERFK LF  +S W  ED++  I++L   GM     IM++ R
Sbjct:  229 EIIETVLNKFAVQEQEAENNT-WRLRIPFIAQWYGIQALRKYVSGISMPIDEFLIKWKSLFPPFFPCDIDIDMLRGY---HFKPTDKTVQYIAKSTLPMDPKERFKVLFRLQSQWDLEDIKPLIEELNSRGMKIDSFIMKYAR 367

[Close]

BLAST of DNA replication and sister chromatid cohesion 1 vs. Ensembl Nematostella
Match: EDO31491 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SXS6])

HSP 1 Score: 87.0409 bits (214), Expect = 2.030e-21
Identity = 66/266 (24.81%), Postives = 135/266 (50.75%), Query Frame = 2

Query:  392 VSSTCNKFYEVNLRKSKIGQVYKILQRSILYHHIDENTNEEI-------YTFEKLLEVVIMSEEELKNALRELKVYNVDGHLRLLXXXXXXXXXXXXXECSFENDFSIFDVSQNNVQFMLNDLFPIEILDQTLNYYFVKLIEKDGDTIWKINIIE--VTRCFAEFILNKSDEMKLEEFLVMWNEKLPEDLNGDINNLHGLVIINETSQPNSVKLVKFLTLSDEPEERFKELFLQKSHWQQEDLEGYIKDLVPPGMSASQLIMRFCR 1162
            VSS  +++ EV   + ++ ++ ++L++++      EN  +++       +T + LL VV  SE+E+K  L +L    ++GH RLL  DY     ++I+    E  +    V  +     L +L P  + +  L +Y  KL +   + +   +++E  + R +AE++L  +      EF+  W + +P+ +   + +L G+ + +  S P  +       L +EPE RF +LF  ++ W  ++++ YI+DLV  G   + L++++ R
Sbjct:   78 VSSCHSEYLEVRSGRPRLQKLRRLLEQAMYKGPEYENKGDDMTDGIREKFTLDDLLNVVQGSEQEIKQKLDKLGALEINGHWRLLEKDYEERATMRILTYLEEMAWDYQRVPLDECCDGLKELQPSFVTEYCLRHY-GKLCDGCMEEV-HYHLLEDKICRFYAEYLLRPAGRFNYHEFMESWQQSVPDGMTTTLEHLQGIALTDMKSHPPVIWHFPASDLPEEPEIRFNKLFKTRNKWTFDEIQPYIRDLVGTGQPLNSLLLKYAR 341

HSP 2 Score: 33.113 bits (74), Expect = 2.030e-21
Identity = 14/37 (37.84%), Postives = 26/37 (70.27%), Query Frame = 3

Query:  216 QPNSFVIKGKTNDIAVLCTNNKSYEIREAETSNALLI 326
            Q  S VI+G+  + A+L + + ++E++ A+TSN LL+
Sbjct:   20 QGESLVIRGENQEEALLFSKDTTFEVKLADTSNTLLL 56

[Close]

BLAST of DNA replication and sister chromatid cohesion 1 vs. Ensembl Nematostella
Match: EDO27880 (pep supercontig:ASM20922v1:NEMVEscaffold_3045:5789:8211:-1 gene:NEMVEDRAFT_v1g149608 transcript:EDO27880 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 68.9366 bits (167), Expect = 3.025e-14
Identity = 29/111 (26.13%), Postives = 60/111 (54.05%), Query Frame = 2

Query:  833 EVTRCFAEFILNKSDEMKLEEFLVMWNEKLPEDLNGDINNLHGLVIINETSQPNSVKLVKFLTLSDEPEERFKELFLQKSHWQQEDLEGYIKDLVPPGMSASQLIMRFCRC 1165
            ++ R +AE++L  +      EF+  W + +P+ +   + +L G+ + +  S P  +       L +EPE RF +LF  ++ W  ++++ YI+DLV  G   + L++++ R 
Sbjct:   10 KICRFYAEYLLRPAGRFNYHEFMESWQQSVPDGMTTTLEHLQGIALTDMKSHPPVIWHFPASDLPEEPEIRFNKLFKTRNKWTFDEIQPYIRDLVGTGQPLNSLLLKYARS 120

[Close]

BLAST of DNA replication and sister chromatid cohesion 1 vs. Ensembl Medaka
Match: dscc1 (DNA replication and sister chromatid cohesion 1 [Source:NCBI gene;Acc:101155795])

HSP 1 Score: 105.916 bits (263), Expect = 7.161e-25
Identity = 67/238 (28.15%), Postives = 123/238 (51.68%), Query Frame = 2

Query:  497 ENTNEEIYTFEKLLEVVIMSEEELKNALRELKVYNVDGHLRLLXXXXXXXXXXXXXECSFENDFSIFDVSQNNVQFMLNDLFPIE---ILDQTLNYYFVKLIEKDGDTIWKINIIEVTRCFAEFILNKSDEMKLEEFLVMWNEKLPEDLNGDINNLHGLVIINETSQPNSVKLVKFLTLSDEPEERFKELFLQKSHWQQEDLEGYIKDLVPPGMSASQLIMRFCRCINNAKIKTFSKR 1201
            E   E  YT + LLE +  SEEE+K+ L  +    +DG+ R+L  DY   ++  + +      +S   V    +Q  L++L P+E   +++  LN Y  +  E D +  + +N  +V R  A  +L  + +  L+EF  +W + +PE ++  ++ L G+ +++ TS P ++ L++   L ++ +ERF  LF  +  W +ED+  YI+DL     S   L+ ++ R      +K F+ R
Sbjct:  153 EEKTENRYTMQDLLERIQASEEEIKSHLEIIHASQIDGYWRVLDFDYEMKLLGHVTQLVDSESWSFNKVP---LQTSLDELAPLEPRQMIEHCLNCYGKRYTEND-EVFYALNETKVCRGLALLLLQNAIKFNLKEFQEVWQQSVPEGMSTRLDQLKGVALVDRTSHPETIGLLRVEDLPEDTQERFSHLFTLREKWTEEDITPYIRDLCGEKQSTGALLTKYARSSMQNGMKVFNSR 386

[Close]

BLAST of DNA replication and sister chromatid cohesion 1 vs. Planmine SMEST
Match: SMESG000022220.1 (SMESG000022220.1)

HSP 1 Score: 455.292 bits (1170), Expect = 5.488e-169
Identity = 248/267 (92.88%), Postives = 250/267 (93.63%), Query Frame = 2

Query:  341 IKFQ*QRKRAFINQLITVSSTCNKFYEVNLRKSKIGQVYKILQRSILYHHIDENTNEEIYTFEKLLEVVIMSEEELKNALRELKVYNVDGHLRLLXXXXXXXXXXXXXECSFENDFSIFDVSQNNVQFMLNDLFPIEILDQTLNYYFVKLIEKDGDTIWK------INIIEVTRCFAEFILNKSDEMKLEEFLVMWNEKLPEDLNGDINNLHGLVIINETSQPNSVKLVKFLTLSDEPEERFKELFLQKSHWQQEDLEGYIKDLVPP 1123
            + F  + K  FINQLITVSSTCNKFYEVNLRKSKIGQVYKILQRSILYHHIDENTNEEIYTFEKLLEVVIMSEEELKNALRELKVYNVDGHLRLLYIDYIYDIIVKIIECSFENDFSIFDVSQNNVQ MLNDLFPIEILDQTLNYYFVKLIEKD DTIWK      I  I VTRCFAEFILNKSDEMKLEEFLVMWNEKLPEDLNGDINNLHGLVIINETSQPNSVKLVKFLTLSDEPEERFKELFLQKSHWQQEDLEGYIKDLVPP
Sbjct:   99 LNFNNKEKEPFINQLITVSSTCNKFYEVNLRKSKIGQVYKILQRSILYHHIDENTNEEIYTFEKLLEVVIMSEEELKNALRELKVYNVDGHLRLLYIDYIYDIIVKIIECSFENDFSIFDVSQNNVQSMLNDLFPIEILDQTLNYYFVKLIEKDRDTIWKINIIELIIKISVTRCFAEFILNKSDEMKLEEFLVMWNEKLPEDLNGDINNLHGLVIINETSQPNSVKLVKFLTLSDEPEERFKELFLQKSHWQQEDLEGYIKDLVPP 365

HSP 2 Score: 159.073 bits (401), Expect = 5.488e-169
Identity = 92/93 (98.92%), Postives = 93/93 (100.00%), Query Frame = 3

Query:   48 MISTQNCEDILNLIKCSPESFSKISQTIVFGEDFAKEGCYIFKXXXXXXXXXXXXXQPNSFVIKGKTNDIAVLCTNNKSYEIREAETSNALLI 326
            M+STQNCEDILNLIKCSPESFSKISQTIVFGEDFAKEGCYIFKINNEILESLNSNSQPNSFVIKGKTNDIAVLCTNNKSYEIREAETSNALLI
Sbjct:    1 MLSTQNCEDILNLIKCSPESFSKISQTIVFGEDFAKEGCYIFKINNEILESLNSNSQPNSFVIKGKTNDIAVLCTNNKSYEIREAETSNALLI 93

[Close]

BLAST of DNA replication and sister chromatid cohesion 1 vs. Planmine SMEST
Match: SMESG000048533.1 (SMESG000048533.1)

HSP 1 Score: 159.844 bits (403), Expect = 2.271e-78
Identity = 92/93 (98.92%), Postives = 93/93 (100.00%), Query Frame = 3

Query:   48 MISTQNCEDILNLIKCSPESFSKISQTIVFGEDFAKEGCYIFKXXXXXXXXXXXXXQPNSFVIKGKTNDIAVLCTNNKSYEIREAETSNALLI 326
            M+STQNCEDILNLIKCSPESFSKISQTIVFGEDFAKEGCYIFKINNEILESLNSNSQPNSFVIKGKTNDIAVLCTNNKSYEIREAETSNALLI
Sbjct:    1 MLSTQNCEDILNLIKCSPESFSKISQTIVFGEDFAKEGCYIFKINNEILESLNSNSQPNSFVIKGKTNDIAVLCTNNKSYEIREAETSNALLI 93

HSP 2 Score: 152.14 bits (383), Expect = 2.271e-78
Identity = 77/85 (90.59%), Postives = 79/85 (92.94%), Query Frame = 2

Query:  341 IKFQ*QRKRAFINQLITVSSTCNKFYEVNLRKSKIGQVYKILQRSILYHHIDENTNEEIYTFEKLLEVVIMSEEELKNALRELKV 595
            + F  + K  FINQLITVSSTCNKFYEVNLRKSKIGQVYKILQRSILYHHIDENTNEEIYTFEKLLEVVIMSEEELKNALRELKV
Sbjct:   99 LNFNNKEKEPFINQLITVSSTCNKFYEVNLRKSKIGQVYKILQRSILYHHIDENTNEEIYTFEKLLEVVIMSEEELKNALRELKV 183

HSP 3 Score: 226.483 bits (576), Expect = 2.045e-70
Identity = 107/109 (98.17%), Postives = 109/109 (100.00%), Query Frame = 2

Query:  830 IEVTRCFAEFILNKSDEMKLEEFLVMWNEKLPEDLNGDINNLHGLVIINETSQPNSVKLVKFLTLSDEPEERFKELFLQKSHWQQEDLEGYIKDLVPPGMSASQLIMRF 1156
            ++VTRCFAEFILNKSDEMKLEEFLVMWNEKLPEDLNGDINNLHGLVIINETSQPNSVKLVKFLTLSDEPEERFKELFLQKSHWQQEDLEGYIKDLVPPGMSASQLIMRF
Sbjct:  181 LKVTRCFAEFILNKSDEMKLEEFLVMWNEKLPEDLNGDINNLHGLVIINETSQPNSVKLVKFLTLSDEPEERFKELFLQKSHWQQEDLEGYIKDLVPPGMSASQLIMRF 289

[Close]

BLAST of DNA replication and sister chromatid cohesion 1 vs. Planmine SMEST
Match: SMESG000022220.1 (SMESG000022220.1)

HSP 1 Score: 158.688 bits (400), Expect = 7.521e-78
Identity = 92/93 (98.92%), Postives = 93/93 (100.00%), Query Frame = 3

Query:   48 MISTQNCEDILNLIKCSPESFSKISQTIVFGEDFAKEGCYIFKXXXXXXXXXXXXXQPNSFVIKGKTNDIAVLCTNNKSYEIREAETSNALLI 326
            M+STQNCEDILNLIKCSPESFSKISQTIVFGEDFAKEGCYIFKINNEILESLNSNSQPNSFVIKGKTNDIAVLCTNNKSYEIREAETSNALLI
Sbjct:    1 MLSTQNCEDILNLIKCSPESFSKISQTIVFGEDFAKEGCYIFKINNEILESLNSNSQPNSFVIKGKTNDIAVLCTNNKSYEIREAETSNALLI 93

HSP 2 Score: 151.754 bits (382), Expect = 7.521e-78
Identity = 77/85 (90.59%), Postives = 79/85 (92.94%), Query Frame = 2

Query:  341 IKFQ*QRKRAFINQLITVSSTCNKFYEVNLRKSKIGQVYKILQRSILYHHIDENTNEEIYTFEKLLEVVIMSEEELKNALRELKV 595
            + F  + K  FINQLITVSSTCNKFYEVNLRKSKIGQVYKILQRSILYHHIDENTNEEIYTFEKLLEVVIMSEEELKNALRELKV
Sbjct:   99 LNFNNKEKEPFINQLITVSSTCNKFYEVNLRKSKIGQVYKILQRSILYHHIDENTNEEIYTFEKLLEVVIMSEEELKNALRELKV 183

HSP 3 Score: 202.216 bits (513), Expect = 3.801e-62
Identity = 96/98 (97.96%), Postives = 98/98 (100.00%), Query Frame = 2

Query:  830 IEVTRCFAEFILNKSDEMKLEEFLVMWNEKLPEDLNGDINNLHGLVIINETSQPNSVKLVKFLTLSDEPEERFKELFLQKSHWQQEDLEGYIKDLVPP 1123
            ++VTRCFAEFILNKSDEMKLEEFLVMWNEKLPEDLNGDINNLHGLVIINETSQPNSVKLVKFLTLSDEPEERFKELFLQKSHWQQEDLEGYIKDLVPP
Sbjct:  181 LKVTRCFAEFILNKSDEMKLEEFLVMWNEKLPEDLNGDINNLHGLVIINETSQPNSVKLVKFLTLSDEPEERFKELFLQKSHWQQEDLEGYIKDLVPP 278

The following BLAST results are available for this feature:

BLAST of DNA replication and sister chromatid cohesion 1 vs. Ensembl Human
BLAST of DNA replication and sister chromatid cohesion 1 vs. Ensembl Celegans
BLAST of DNA replication and sister chromatid cohesion 1 vs. Ensembl Fly
BLAST of DNA replication and sister chromatid cohesion 1 vs. Ensembl Zebrafish
BLAST of DNA replication and sister chromatid cohesion 1 vs. Ensembl Xenopus
BLAST of DNA replication and sister chromatid cohesion 1 vs. Ensembl Mouse
BLAST of DNA replication and sister chromatid cohesion 1 vs. UniProt/SwissProt
BLAST of DNA replication and sister chromatid cohesion 1 vs. TrEMBL
BLAST of DNA replication and sister chromatid cohesion 1 vs. Ensembl Cavefish
BLAST of DNA replication and sister chromatid cohesion 1 vs. Ensembl Sea Lamprey
BLAST of DNA replication and sister chromatid cohesion 1 vs. Ensembl Yeast
BLAST of DNA replication and sister chromatid cohesion 1 vs. Ensembl Nematostella
BLAST of DNA replication and sister chromatid cohesion 1 vs. Ensembl Medaka
BLAST of DNA replication and sister chromatid cohesion 1 vs. Planmine SMEST

BLAST of DNA replication and sister chromatid cohesion 1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 1


Match Name	E-value	Identity	Description
DSCC1	3.359e-20	25.42	DNA replication and sister chromatid cohesion 1 [S...	[more]

BLAST of DNA replication and sister chromatid cohesion 1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of DNA replication and sister chromatid cohesion 1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 1


Match Name	E-value	Identity	Description
CG11788	2.453e-16	26.43	gene:FBgn0034495 transcript:FBtr0086277	[more]

BLAST of DNA replication and sister chromatid cohesion 1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 1


Match Name	E-value	Identity	Description
dscc1	5.468e-22	26.32	DNA replication and sister chromatid cohesion 1 [S...	[more]

BLAST of DNA replication and sister chromatid cohesion 1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 1


Match Name	E-value	Identity	Description
dscc1	8.224e-21	27.54	DNA replication and sister chromatid cohesion 1 [S...	[more]

BLAST of DNA replication and sister chromatid cohesion 1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 2


Match Name	E-value	Identity	Description
Dscc1	6.303e-20	26.27	DNA replication and sister chromatid cohesion 1 [S...	[more]
Dscc1	6.551e-15	26.49	DNA replication and sister chromatid cohesion 1 [S...	[more]

BLAST of DNA replication and sister chromatid cohesion 1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q66I84\|DCC1_DANRE	2.111e-21	26.75	Sister chromatid cohesion protein DCC1 OS=Danio re...	[more]
sp\|Q6GMB0\|DCC1_XENLA	5.823e-21	28.38	Sister chromatid cohesion protein DCC1 OS=Xenopus ...	[more]
sp\|Q6GL75\|DCC1_XENTR	4.357e-20	27.54	Sister chromatid cohesion protein DCC1 OS=Xenopus ...	[more]
sp\|Q9BVC3\|DCC1_HUMAN	1.613e-19	25.42	Sister chromatid cohesion protein DCC1 OS=Homo sap...	[more]
sp\|Q14AI0\|DCC1_MOUSE	4.409e-19	26.27	Sister chromatid cohesion protein DCC1 OS=Mus musc...	[more]

BLAST of DNA replication and sister chromatid cohesion 1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
T1FMB4	2.331e-31	25.48	Uncharacterized protein OS=Helobdella robusta OX=6...	[more]
D6WSW4	1.582e-28	26.50	Sister chromatid cohesion protein DCC1-like Protei...	[more]
A0A023F1I3	6.484e-28	24.81	Uncharacterized protein (Fragment) OS=Triatoma inf...	[more]
A0A067REG9	9.467e-28	25.55	Sister chromatid cohesion protein DCC1 OS=Zootermo...	[more]
A0A1S3IFT1	2.553e-27	25.98	sister chromatid cohesion protein DCC1 isoform X2 ...	[more]

BLAST of DNA replication and sister chromatid cohesion 1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 2


Match Name	E-value	Identity	Description
dscc1	7.172e-21	26.41	DNA replication and sister chromatid cohesion 1 [S...	[more]
dscc1	1.213e-17	27.00	DNA replication and sister chromatid cohesion 1 [S...	[more]

BLAST of DNA replication and sister chromatid cohesion 1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1


Match Name	E-value	Identity	Description
dscc1	6.989e-25	24.81	DNA replication and sister chromatid cohesion 1 [S...	[more]

BLAST of DNA replication and sister chromatid cohesion 1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1


Match Name	E-value	Identity	Description
DCC1	2.245e-9	29.37	Subunit of a complex with Ctf8p and Ctf18p; shares...	[more]

BLAST of DNA replication and sister chromatid cohesion 1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 2


Match Name	E-value	Identity	Description
EDO31491	2.030e-21	24.81	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO27880	3.025e-14	26.13	pep supercontig:ASM20922v1:NEMVEscaffold_3045:5789...	[more]

BLAST of DNA replication and sister chromatid cohesion 1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 1


Match Name	E-value	Identity	Description
dscc1	7.161e-25	28.15	DNA replication and sister chromatid cohesion 1 [S...	[more]

BLAST of DNA replication and sister chromatid cohesion 1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 3


Match Name	E-value	Identity	Description
SMESG000022220.1	5.488e-169	92.88	SMESG000022220.1	[more]
SMESG000048533.1	2.271e-78	98.92	SMESG000048533.1	[more]
SMESG000022220.1	7.521e-78	98.92	SMESG000022220.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence
protein sequence

transcript sequence

>SMED30017245 ID=SMED30017245|Name=DNA replication and sister chromatid cohesion 1|organism=Schmidtea mediterranea sexual|type=transcript|length=1226bp
ATTATTATATCTTTGATTATTTTATTATTTTTTATAATAATTTTAAGATG
ATCTCTACACAAAATTGTGAAGATATTCTTAATTTAATTAAATGCTCGCC
CGAATCTTTCAGCAAAATAAGTCAGACAATTGTTTTTGGAGAAGATTTTG
CTAAAGAAGGATGCTACATTTTCAAAATTAATAATGAAATCTTGGAATCT
TTAAATTCAAATTCTCAACCTAATTCGTTTGTTATCAAAGGCAAAACCAA
TGATATAGCTGTATTATGTACTAACAATAAAAGCTACGAAATTCGAGAAG
CTGAAACATCAAACGCATTGTTAATATTGCCAAATTTGGAATTAAATTTC
AATAACAAAGAAAAAGAGCCTTTATTAATCAGCTAATAACAGTATCATCA
ACATGTAATAAATTTTATGAAGTCAATTTGCGAAAATCCAAAATCGGTCA
AGTCTATAAAATTTTACAGCGCTCGATTCTTTATCATCATATAGATGAAA
ACACAAACGAAGAAATTTACACGTTTGAAAAGTTGTTAGAAGTCGTTATA
ATGAGTGAGGAAGAATTAAAAAATGCTTTGCGTGAACTTAAGGTTTATAA
TGTTGATGGCCATTTACGATTACTTTATATTGATTATATATATGACATTA
TAGTCAAAATAATTGAATGTTCATTTGAAAATGATTTTAGTATTTTTGAT
GTTTCACAAAATAATGTGCAATTTATGTTAAATGATTTATTTCCCATTGA
GATTTTAGATCAAACTTTGAACTATTATTTTGTAAAACTGATAGAAAAAG
ATGGAGATACTATTTGGAAAATTAATATTATTGAGGTAACACGATGTTTT
GCAGAATTTATACTTAATAAGTCAGATGAAATGAAACTGGAAGAATTTTT
AGTGATGTGGAATGAAAAGCTTCCTGAAGATTTGAATGGAGACATAAACA
ATTTACATGGGCTTGTTATTATCAATGAAACATCGCAACCAAATTCTGTT
AAATTAGTGAAATTTCTAACACTTTCTGATGAACCCGAAGAAAGATTTAA
GGAGCTGTTTCTACAGAAATCTCATTGGCAACAAGAAGATCTTGAAGGAT
ATATCAAAGATCTTGTTCCCCCCGGAATGTCTGCTTCTCAGCTAATTATG
CGGTTTTGTAGGTGCATCAATAATGCAAAAATTAAAACATTTTCAAAGCG
TTAATAAATATTTCAGTGTCTTCCAC

protein sequence of SMED30017245-orf-1

>SMED30017245-orf-1 ID=SMED30017245-orf-1|Name=SMED30017245-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=128bp
YYIFDYFIIFYNNFKMISTQNCEDILNLIKCSPESFSKISQTIVFGEDFA
KEGCYIFKINNEILESLNSNSQPNSFVIKGKTNDIAVLCTNNKSYEIREA
ETSNALLILPNLELNFNNKEKEPLLIS*

protein sequence of SMED30017245-orf-2

>SMED30017245-orf-2 ID=SMED30017245-orf-2|Name=SMED30017245-orf-2|organism=Schmidtea mediterranea sexual|type=polypeptide|length=218bp
MSEEELKNALRELKVYNVDGHLRLLYIDYIYDIIVKIIECSFENDFSIFD
VSQNNVQFMLNDLFPIEILDQTLNYYFVKLIEKDGDTIWKINIIEVTRCF
AEFILNKSDEMKLEEFLVMWNEKLPEDLNGDINNLHGLVIINETSQPNSV
KLVKFLTLSDEPEERFKELFLQKSHWQQEDLEGYIKDLVPPGMSASQLIM
RFCRCINNAKIKTFSKR*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **biological process**
Term	Definition
GO:0007064	mitotic sister chromatid cohesion
GO:0006260	DNA replication
GO:0006275	regulation of DNA replication
GO:0007049	cell cycle
GO:0034088	maintenance of mitotic sister chromatid cohesion

Vocabulary: **cellular component**
Term	Definition
GO:0031390	Ctf18 RFC-like complex
GO:0000785	chromatin
GO:0005634	nucleus

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000014	zeta neoblast
PLANA:0000420	parapharyngeal region
PLANA:0000429	neoblast
PLANA:0002109	X1 cell

Vocabulary: **INTERPRO**
Term	Definition
IPR019128	Dcc1

Vocabulary: **molecular function**
Term	Definition
GO:0003677	DNA binding

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR019128	Sister chromatid cohesion protein Dcc1	PFAM	PF09724	Dcc1	coord: 58..122 e-value: 1.0E-14 score: 54.6

Main menu

DNA replication and sister chromatid cohesion 1

Zeng et. al., 2018

▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 6

Owlery

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