Thioredoxin

Overview
NameThioredoxin
Smed IDSMED30017237
Length (bp)516
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Thioredoxin (SMED30017237) t-SNE clustered cells

Violin plots show distribution of expression levels for Thioredoxin (SMED30017237) in cells (dots) of each of the 12 neoblast clusters.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30017237

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 2

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
reproductive organSMED30017237SMESG000023196.1 Contig46762newmark_estsPMID:28434803
Rouhana et al., 2017		whole organism adult hermaphrodite RNA-sequencing evidence
reproductive organSMED30017237SMESG000023196.1 Contig46762uc_Smed_v2PMID:28434803
Rouhana et al., 2017		whole organism adult hermaphrodite RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Thioredoxin vs. Ensembl Human
Match: TXN (thioredoxin [Source:HGNC Symbol;Acc:HGNC:12435])

HSP 1 Score: 83.5741 bits (205), Expect = 8.338e-21
Identity = 37/100 (37.00%), Postives = 56/100 (56.00%), Query Frame = 3 
Query:  120 VIHISSMNDFVRRIDQNGK--IIADFSASWCGPCNNIAPIYEDLSETYDKISFLKIDVDSQSDIATLYNITSLPTFVFFNHGAQIHMIIGADVNQLKSNL 413
            V  I S   F   +D  G   ++ DFSA+WCGPC  I P +  LSE Y  + FL++DVD   D+A+   +  +PTF FF  G ++    GA+  +L++ +
Sbjct:    2 VKQIESKTAFQEALDAAGDKLVVVDFSATWCGPCKMIKPFFHSLSEKYSNVIFLEVDVDDCQDVASECEVKCMPTFQFFKKGQKVGEFSGANKEKLEATI 101
[Close]
BLAST of Thioredoxin vs. Ensembl Human
Match: TXNDC2 (thioredoxin domain containing 2 [Source:HGNC Symbol;Acc:HGNC:16470])

HSP 1 Score: 67.0106 bits (162), Expect = 5.963e-13
Identity = 35/104 (33.65%), Postives = 55/104 (52.88%), Query Frame = 3 
Query:  129 ISSMNDFVRRIDQNGK--IIADFSASWCGPCNNIAPIYEDLSETYDKISFLKIDVDSQSDIATLYNITSLPTFVFFNHGAQIHMIIGADVNQLKSNLEKFNAEI 434
            I S  DF   + + G+  +  DFSA+WCGPC  I P +  LS  ++ + FL++D D+  ++     I  +PTF F+    ++  + GA    LK  LE   AE+
Sbjct:  453 ILSKEDFEASLKEAGERLVAVDFSATWCGPCRTIRPFFHALSVKHEDVVFLEVDADNCEEVVRECAIMCVPTFQFYKKEEKVDELCGA----LKEKLEAVIAEL 552
[Close]
BLAST of Thioredoxin vs. Ensembl Human
Match: TXNDC2 (thioredoxin domain containing 2 [Source:HGNC Symbol;Acc:HGNC:16470])

HSP 1 Score: 67.0106 bits (162), Expect = 6.334e-13
Identity = 35/104 (33.65%), Postives = 55/104 (52.88%), Query Frame = 3 
Query:  129 ISSMNDFVRRIDQNGK--IIADFSASWCGPCNNIAPIYEDLSETYDKISFLKIDVDSQSDIATLYNITSLPTFVFFNHGAQIHMIIGADVNQLKSNLEKFNAEI 434
            I S  DF   + + G+  +  DFSA+WCGPC  I P +  LS  ++ + FL++D D+  ++     I  +PTF F+    ++  + GA    LK  LE   AE+
Sbjct:  438 ILSKEDFEASLKEAGERLVAVDFSATWCGPCRTIRPFFHALSVKHEDVVFLEVDADNCEEVVRECAIMCVPTFQFYKKEEKVDELCGA----LKEKLEAVIAEL 537
[Close]
BLAST of Thioredoxin vs. Ensembl Human
Match: TXN2 (thioredoxin 2 [Source:HGNC Symbol;Acc:HGNC:17772])

HSP 1 Score: 63.929 bits (154), Expect = 1.085e-12
Identity = 27/92 (29.35%), Postives = 53/92 (57.61%), Query Frame = 3 
Query:  153 RRIDQNGKIIADFSASWCGPCNNIAPIYEDL-SETYDKISFLKIDVDSQSDIATLYNITSLPTFVFFNHGAQIHMIIG-ADVNQLKSNLEKF 422
            R ++    ++ DF A WCGPC  + P  E + ++ + K+   K+D+D  +D+A  Y ++++PT +   +G  +   +G  D +QL++ L+K 
Sbjct:   73 RVVNSETPVVVDFHAQWCGPCKILGPRLEKMVAKQHGKVVMAKVDIDDHTDLAIEYEVSAVPTVLAMKNGDVVDKFVGIKDEDQLEAFLKKL 164
[Close]
BLAST of Thioredoxin vs. Ensembl Human
Match: TXN2 (thioredoxin 2 [Source:HGNC Symbol;Acc:HGNC:17772])

HSP 1 Score: 63.929 bits (154), Expect = 1.085e-12
Identity = 27/92 (29.35%), Postives = 53/92 (57.61%), Query Frame = 3 
Query:  153 RRIDQNGKIIADFSASWCGPCNNIAPIYEDL-SETYDKISFLKIDVDSQSDIATLYNITSLPTFVFFNHGAQIHMIIG-ADVNQLKSNLEKF 422
            R ++    ++ DF A WCGPC  + P  E + ++ + K+   K+D+D  +D+A  Y ++++PT +   +G  +   +G  D +QL++ L+K 
Sbjct:   73 RVVNSETPVVVDFHAQWCGPCKILGPRLEKMVAKQHGKVVMAKVDIDDHTDLAIEYEVSAVPTVLAMKNGDVVDKFVGIKDEDQLEAFLKKL 164
[Close]
BLAST of Thioredoxin vs. Ensembl Celegans
Match: trx-1 (Thioredoxin-1 [Source:UniProtKB/Swiss-Prot;Acc:Q09433])

HSP 1 Score: 90.1225 bits (222), Expect = 8.659e-24
Identity = 41/108 (37.96%), Postives = 69/108 (63.89%), Query Frame = 3 
Query:  117 PVIHISSMNDFVRRIDQNGK--IIADFSASWCGPCNNIAPIYEDLSETYDKISFLKIDVDSQSDIATLYNITSLPTFVFFNHGAQIHMIIGADVNQLKSN-LEKFNAE 431
            P++ ++ M+DF + I Q+ +  II DF A+WCGPC  IAP+Y++L+ T+  I F K+DVD   D+ + Y++  +PTF+F  +G  I  + G   ++L+   LE  +A+
Sbjct:    7 PILELADMSDFEQLIRQHPEKIIILDFYATWCGPCKAIAPLYKELATTHKGIIFCKVDVDEAEDLCSKYDVKMMPTFIFTKNGDAIEALEGCVEDELRQKVLEHVSAQ 114
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BLAST of Thioredoxin vs. Ensembl Celegans
Match: Y55F3AR.2 (pep chromosome:WBcel235:IV:1094545:1096723:1 gene:WBGene00021933.1 transcript:Y55F3AR.2.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:Y55F3AR.2)

HSP 1 Score: 93.9745 bits (232), Expect = 9.935e-24
Identity = 46/105 (43.81%), Postives = 65/105 (61.90%), Query Frame = 3 
Query:  114 MPVIHISSMNDFVRRIDQ-NGK-IIADFSASWCGPCNNIAPIYEDLSETYDKISFLKIDVDSQSDIATLYNITSLPTFVFFNHGAQIHMIIGADVNQLKSNLEKF 422
            MPVI ++  +DF R+    NGK +  DF+ASWCGPC  IAPI+ DL+  Y    FLK+DVD     A  Y + ++PTF+ F +G +   I GAD + L+S + K+
Sbjct:    1 MPVIVVNGDSDFDRKFSAGNGKAVFVDFTASWCGPCQYIAPIFSDLANQYKGSVFLKVDVDECRGTAATYGVNAMPTFIAFVNGQKKATIQGADESGLRSMVAKY 105
[Close]
BLAST of Thioredoxin vs. Ensembl Celegans
Match: png-1 (Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase [Source:UniProtKB/Swiss-Prot;Acc:Q9TW67])

HSP 1 Score: 94.3597 bits (233), Expect = 7.226e-23
Identity = 44/122 (36.07%), Postives = 68/122 (55.74%), Query Frame = 3 
Query:  114 MPVIHISSM---NDFVRRIDQNGKIIADFSASWCGPCNNIAPIYEDLSETYDKISFLKIDVDSQSDIATLYNITSLPTFVFFNHGAQIHMIIGADVNQLKSNLEKFNAEIDKKISTMSESVK 470
            MPV  + S+   N+ + R D N  II DF A+WCGPC  I+PI+E  S  Y   +FLK++ D   DI   YNI+++PTF+F  +  Q+ M+ GA+   +   + +  +      +  S+S K
Sbjct:    1 MPVTEVGSLPELNNILERSDANRLIIIDFFANWCGPCRMISPIFEQFSAEYGNATFLKVNCDVARDIVQRYNISAMPTFIFLKNRQQVDMVRGANQQAIAEKIRQHYSPTPANPNAASDSEK 122
[Close]
BLAST of Thioredoxin vs. Ensembl Celegans
Match: trx-1 (Thioredoxin-1 [Source:UniProtKB/Swiss-Prot;Acc:Q09433])

HSP 1 Score: 81.6481 bits (200), Expect = 2.158e-20
Identity = 39/100 (39.00%), Postives = 63/100 (63.00%), Query Frame = 3 
Query:  141 NDFVRRIDQNGK--IIADFSASWCGPCNNIAPIYEDLSETYDKISFLKIDVDSQSDIATLYNITSLPTFVFFNHGAQIHMIIGADVNQLKSN-LEKFNAE 431
            +DF + I Q+ +  II DF A+WCGPC  IAP+Y++L+ T+  I F K+DVD   D+ + Y++  +PTF+F  +G  I  + G   ++L+   LE  +A+
Sbjct:   16 SDFEQLIRQHPEKIIILDFYATWCGPCKAIAPLYKELATTHKGIIFCKVDVDEAEDLCSKYDVKMMPTFIFTKNGDAIEALEGCVEDELRQKVLEHVSAQ 115
[Close]
BLAST of Thioredoxin vs. Ensembl Celegans
Match: txl-1 (ThioredoXin-Like; Thioredoxin-like protein; Thioredoxin-like protein TXL [Source:UniProtKB/TrEMBL;Acc:G5EES9])

HSP 1 Score: 84.3445 bits (207), Expect = 6.097e-20
Identity = 39/105 (37.14%), Postives = 61/105 (58.10%), Query Frame = 3 
Query:  114 MPVIHISSMNDFVRRIDQNG--KIIADFSASWCGPCNNIAPIYEDLSETYDKISFLKIDVDSQSDIATLYNITSLPTFVFFNHGAQIHMIIGADVNQLKSNLEKF 422
            MPVI++    DF  ++   G   +I DF+A WCGPC  IAP +E LS  Y    FLK+DV+     ++   + S+PTF+ F  G ++  + GAD   L++ ++K+
Sbjct:    1 MPVINVKDDEDFRNQLSLAGLKSVIVDFTAVWCGPCKMIAPTFEALSNQYLGAVFLKVDVEICEKTSSENGVNSMPTFMVFQSGVRVEQMKGADAKALETMVKKY 105
[Close]
BLAST of Thioredoxin vs. Ensembl Fly
Match: Txl (gene:FBgn0035631 transcript:FBtr0077098)

HSP 1 Score: 87.8113 bits (216), Expect = 3.850e-21
Identity = 41/104 (39.42%), Postives = 63/104 (60.58%), Query Frame = 3 
Query:  114 MPVIHISSMNDFVRRIDQNG--KIIADFSASWCGPCNNIAPIYEDLSETYDKISFLKIDVDSQSDIATLYNITSLPTFVFFNHGAQIHMIIGADVNQLKSNLEK 419
            M V  I+  + F   + Q G   ++ DF+ASWCGPC  IAPI+E     Y K  FLK+DVD   D A    ++++PTF+F+ +  +I  + GADVN L++ +++
Sbjct:    1 MSVRVINDESHFQAELAQAGIQLVVVDFTASWCGPCKRIAPIFETFPTKYPKAIFLKVDVDKCQDTAAGQGVSAMPTFIFYRNRTKIDRVQGADVNGLEAKIQE 104
[Close]
BLAST of Thioredoxin vs. Ensembl Fly
Match: Trx-2 (gene:FBgn0040070 transcript:FBtr0079840)

HSP 1 Score: 77.7962 bits (190), Expect = 7.343e-19
Identity = 36/81 (44.44%), Postives = 53/81 (65.43%), Query Frame = 3 
Query:  168 NGKIIA-DFSASWCGPCNNIAPIYEDLSETY-DKISFLKIDVDSQSDIATLYNITSLPTFVFFNHGAQIHMIIGADVNQLK 404
            +GK++  DF A+WCGPC  I+P   +LS  + D +  LK+DVD   DIA  YNI+S+PTFVF  +G ++    GA+  +L+
Sbjct:   19 SGKLVVLDFFATWCGPCKMISPKLVELSTQFADNVVVLKVDVDECEDIAMEYNISSMPTFVFLKNGVKVEEFAGANAKRLE 99
[Close]
BLAST of Thioredoxin vs. Ensembl Fly
Match: Trx-2 (gene:FBgn0040070 transcript:FBtr0079839)

HSP 1 Score: 77.7962 bits (190), Expect = 7.343e-19
Identity = 36/81 (44.44%), Postives = 53/81 (65.43%), Query Frame = 3 
Query:  168 NGKIIA-DFSASWCGPCNNIAPIYEDLSETY-DKISFLKIDVDSQSDIATLYNITSLPTFVFFNHGAQIHMIIGADVNQLK 404
            +GK++  DF A+WCGPC  I+P   +LS  + D +  LK+DVD   DIA  YNI+S+PTFVF  +G ++    GA+  +L+
Sbjct:   19 SGKLVVLDFFATWCGPCKMISPKLVELSTQFADNVVVLKVDVDECEDIAMEYNISSMPTFVFLKNGVKVEEFAGANAKRLE 99
[Close]
BLAST of Thioredoxin vs. Ensembl Fly
Match: TrxT (gene:FBgn0029752 transcript:FBtr0070755)

HSP 1 Score: 77.7962 bits (190), Expect = 2.013e-18
Identity = 33/82 (40.24%), Postives = 52/82 (63.41%), Query Frame = 3 
Query:  177 IIADFSASWCGPCNNIAPIYEDLSETY-DKISFLKIDVDSQSDIATLYNITSLPTFVFFNHGAQIHMIIGADVNQLKSNLEK 419
            ++ DF A WCGPC  IAP  ++L++ Y D++  LK++VD   DI   YN+ S+PTFVF   G  + + +G + ++L   +EK
Sbjct:   23 VVIDFYADWCGPCKIIAPKLDELAQQYSDRVVVLKVNVDENEDITVEYNVNSMPTFVFIKGGNVLELFVGCNSDKLAKLMEK 104
[Close]
BLAST of Thioredoxin vs. Ensembl Fly
Match: TrxT (gene:FBgn0029752 transcript:FBtr0340478)

HSP 1 Score: 77.7962 bits (190), Expect = 2.013e-18
Identity = 33/82 (40.24%), Postives = 52/82 (63.41%), Query Frame = 3 
Query:  177 IIADFSASWCGPCNNIAPIYEDLSETY-DKISFLKIDVDSQSDIATLYNITSLPTFVFFNHGAQIHMIIGADVNQLKSNLEK 419
            ++ DF A WCGPC  IAP  ++L++ Y D++  LK++VD   DI   YN+ S+PTFVF   G  + + +G + ++L   +EK
Sbjct:   23 VVIDFYADWCGPCKIIAPKLDELAQQYSDRVVVLKVNVDENEDITVEYNVNSMPTFVFIKGGNVLELFVGCNSDKLAKLMEK 104
[Close]
BLAST of Thioredoxin vs. Ensembl Zebrafish
Match: TXN (zgc:56493 [Source:ZFIN;Acc:ZDB-GENE-030131-8581])

HSP 1 Score: 75.0998 bits (183), Expect = 1.101e-17
Identity = 32/83 (38.55%), Postives = 53/83 (63.86%), Query Frame = 3 
Query:  177 IIADFSASWCGPCNNIAPIYEDLSET--YDKISFLKIDVDSQSDIATLYNITSLPTFVFFNHGAQIHMIIGADVNQLKSNLEK 419
            ++ DF+A+WCGPC +IAP Y+ LSE   Y  + FLK+DVD   D+A    I  +PTF F+ +G ++    G++  +L+  +++
Sbjct:   23 VVVDFTATWCGPCQSIAPFYKGLSENPDYSNVVFLKVDVDDAQDVAQSCEIKCMPTFHFYKNGKKLDDFSGSNQTKLEEMVKQ 105
[Close]
BLAST of Thioredoxin vs. Ensembl Zebrafish
Match: txn (thioredoxin [Source:ZFIN;Acc:ZDB-GENE-040718-162])

HSP 1 Score: 72.7886 bits (177), Expect = 6.702e-17
Identity = 33/86 (38.37%), Postives = 55/86 (63.95%), Query Frame = 3 
Query:  177 IIADFSASWCGPCNNIAPIYEDLSETYDK--ISFLKIDVDSQSDIATLYNITSLPTFVFFNHGAQIHMIIGADVNQLKSNLEKFNA 428
            ++ DF+A+WCGPC  I P ++ LSE  +   + FLK+DVD   D+A L  I+ +PTF F+ +G ++    G++ ++L+   EK N+
Sbjct:   23 VVVDFTATWCGPCQTIGPYFKLLSEKPENKNVVFLKVDVDDAQDVAALCGISCMPTFHFYKNGKKVDEFSGSNQSKLE---EKINS 105
[Close]
BLAST of Thioredoxin vs. Ensembl Zebrafish
Match: txn (thioredoxin [Source:ZFIN;Acc:ZDB-GENE-040718-162])

HSP 1 Score: 72.7886 bits (177), Expect = 7.398e-17
Identity = 33/86 (38.37%), Postives = 55/86 (63.95%), Query Frame = 3 
Query:  177 IIADFSASWCGPCNNIAPIYEDLSETYDK--ISFLKIDVDSQSDIATLYNITSLPTFVFFNHGAQIHMIIGADVNQLKSNLEKFNA 428
            ++ DF+A+WCGPC  I P ++ LSE  +   + FLK+DVD   D+A L  I+ +PTF F+ +G ++    G++ ++L+   EK N+
Sbjct:   21 VVVDFTATWCGPCQTIGPYFKLLSEKPENKNVVFLKVDVDDAQDVAALCGISCMPTFHFYKNGKKVDEFSGSNQSKLE---EKINS 103
[Close]
BLAST of Thioredoxin vs. Ensembl Zebrafish
Match: txn2 (thioredoxin 2 [Source:ZFIN;Acc:ZDB-GENE-040426-1795])

HSP 1 Score: 63.5438 bits (153), Expect = 9.842e-13
Identity = 30/97 (30.93%), Postives = 54/97 (55.67%), Query Frame = 3 
Query:  141 NDFVRR-IDQNGKIIADFSASWCGPCNNIAPIYED-LSETYDKISFLKIDVDSQSDIATLYNITSLPTFVFFNHGAQIHMIIG-ADVNQLKSNLEKF 422
            +DF  R I+    ++ DF A WCGPC  + P  E  +++   +++  K+D+D  +D+A  Y ++++PT +    G  I   +G  D +QL + +EK 
Sbjct:   67 DDFTERVINSELPVLIDFHAQWCGPCKILGPRLEKAIAKQKGRVTMAKVDIDEHTDLAIEYGVSAVPTVIAMRGGDVIDQFVGIKDEDQLDTFVEKL 163
[Close]
BLAST of Thioredoxin vs. Ensembl Zebrafish
Match: txnl1 (thioredoxin-like 1 [Source:ZFIN;Acc:ZDB-GENE-040426-701])

HSP 1 Score: 59.3066 bits (142), Expect = 1.244e-10
Identity = 27/80 (33.75%), Postives = 45/80 (56.25%), Query Frame = 3 
Query:  180 IADFSASWCGPCNNIAPIYEDLSETYDKISFLKIDVDSQSDIATLYNITSLPTFVFFNHGAQIHMIIGADVNQLKSNLEK 419
            +  F+ S C PC  IAP +  LS  Y ++ FL++DV      A   NI++ PTF+FF +  ++    GAD + L+  +++
Sbjct:   26 VVKFTMSGCRPCVRIAPAFNMLSNKYPQVVFLEVDVHVCQATAAANNISATPTFLFFRNKVRVDQYQGADASGLEEKIKQ 105
[Close]
BLAST of Thioredoxin vs. Ensembl Xenopus
Match: btg5.3 (B-cell translocation gene 5, gene 3 [Source:Xenbase;Acc:XB-GENE-5805799])

HSP 1 Score: 91.2781 bits (225), Expect = 5.498e-24
Identity = 36/82 (43.90%), Postives = 53/82 (64.63%), Query Frame = 3 
Query:  177 IIADFSASWCGPCNNIAPIYEDLSETYDKISFLKIDVDSQSDIATLYNITSLPTFVFFNHGAQIHMIIGADVNQLKSNLEKF 422
            ++ DF+A WCGPC  IAP +E LS  +  I   K+DVD  SD+A +  I+S+PTF+FF  G Q+    GAD+ +LK  +++ 
Sbjct:   21 VVIDFTAKWCGPCQRIAPDFEKLSTEFPDIVLYKVDVDDASDVAQVCGISSMPTFIFFKSGKQVERFSGADIKKLKETIKRL 102
[Close]
BLAST of Thioredoxin vs. Ensembl Xenopus
Match: ENSXETT00000029198.1 (MGC80314 protein [Source:NCBI gene;Acc:100170420])

HSP 1 Score: 80.8777 bits (198), Expect = 7.498e-20
Identity = 33/92 (35.87%), Postives = 58/92 (63.04%), Query Frame = 3 
Query:  120 VIHISSMNDFVRRIDQNGK--IIADFSASWCGPCNNIAPIYEDLSETYDKISFLKIDVDSQSDIATLYNITSLPTFVFFNHGAQIHMIIGAD 389
            V H+ S+++F   + + G   ++ DF+A+WCGPC  I+P++E LS     + F+K+DVD   D+A   ++  +PTF F+ +G ++H   GA+
Sbjct:    2 VRHVESLDEFQNILKEAGDKLVVVDFTATWCGPCKMISPVFEKLSVENPDVVFIKVDVDDAQDVAAHCDVKCMPTFHFYKNGQKVHEFSGAN 93
[Close]
BLAST of Thioredoxin vs. Ensembl Xenopus
Match: btg5.3 (B-cell translocation gene 5, gene 3 [Source:Xenbase;Acc:XB-GENE-5805799])

HSP 1 Score: 79.7221 bits (195), Expect = 2.527e-19
Identity = 36/94 (38.30%), Postives = 58/94 (61.70%), Query Frame = 3 
Query:  120 VIHISSMNDFVRRIDQNGK--IIADFSASWCGPCNNIAPIYEDLSETYDKISFLKIDVDSQSDIATLYNITSLPTFVFFNHGAQI-----HMII 380
            V +++S+ ++   +   G+  ++ DF+A WCGPC  IAP +E LS  +  I   K+DVD  SD+A +  I+S+PTF+FF  G Q+     H++I
Sbjct:    2 VKYLASVEEYQCALKDAGEKLVVIDFTAKWCGPCQRIAPDFEKLSTEFPDIVLYKVDVDDASDVAQVCGISSMPTFIFFKSGKQVFYSRAHLLI 95
[Close]
BLAST of Thioredoxin vs. Ensembl Xenopus
Match: tnfsf13b (TNF superfamily member 13b [Source:Xenbase;Acc:XB-GENE-482353])

HSP 1 Score: 61.2326 bits (147), Expect = 1.158e-11
Identity = 29/101 (28.71%), Postives = 55/101 (54.46%), Query Frame = 3 
Query:  129 ISSMNDFVRRI-DQNGKIIADFSASWCGPCNNIAPIYED-LSETYDKISFLKIDVDSQSDIATLYNITSLPTFVFFNHGAQIHMIIG-ADVNQLKSNLEKF 422
            +   +DF  R+      ++ DF A WCGPC  +AP  E  +++   K+   K+D+D  +D+A  + ++++PT +   +G  +   +G  D +QL + L+K 
Sbjct:   67 VQDADDFQERVVGSETPVVVDFHAQWCGPCKILAPRLEKVVAKQQGKVVMAKVDIDDHTDLALEFEVSAVPTVLAIKNGDVVDKFVGLKDEDQLDAFLKKL 167
[Close]
BLAST of Thioredoxin vs. Ensembl Xenopus
Match: fabp2 (fatty acid binding protein 2 [Source:Xenbase;Acc:XB-GENE-485137])

HSP 1 Score: 58.5362 bits (140), Expect = 3.409e-11
Identity = 29/82 (35.37%), Postives = 42/82 (51.22%), Query Frame = 3 
Query:  177 IIADFSASWCGPCNNIAPIYEDLSETYDKISFLKIDVDSQSDIATLYNITSLPTFVFFNHGAQIHMIIGADVNQLKSNLEKF 422
            ++ +FS+  CG C  +AP YE L   Y  I   K+ +D    +     ITS PTFVF+    +I    GAD+ QL+  + K 
Sbjct:   23 VLVNFSSHKCGQCTIVAPEYEKLCTEYPDILLYKV-LDDAPKLCQHCEITSTPTFVFYKDRLKIKQFSGADIVQLRETIRKL 103
[Close]
BLAST of Thioredoxin vs. Ensembl Mouse
Match: Txn1 (thioredoxin 1 [Source:MGI Symbol;Acc:MGI:98874])

HSP 1 Score: 75.0998 bits (183), Expect = 9.769e-18
Identity = 28/82 (34.15%), Postives = 50/82 (60.98%), Query Frame = 3 
Query:  177 IIADFSASWCGPCNNIAPIYEDLSETYDKISFLKIDVDSQSDIATLYNITSLPTFVFFNHGAQIHMIIGADVNQLKSNLEKF 422
            ++ DFSA+WCGPC  I P +  L + Y  + FL++DVD   D+A    +  +PTF F+  G ++    GA+  +L++++ ++
Sbjct:   23 VVVDFSATWCGPCKMIKPFFHSLCDKYSNVVFLEVDVDDCQDVAADCEVKCMPTFQFYKKGQKVGEFSGANKEKLEASITEY 104
[Close]
BLAST of Thioredoxin vs. Ensembl Mouse
Match: Txndc8 (thioredoxin domain containing 8 [Source:MGI Symbol;Acc:MGI:1914652])

HSP 1 Score: 73.559 bits (179), Expect = 1.330e-16
Identity = 27/67 (40.30%), Postives = 44/67 (65.67%), Query Frame = 3 
Query:  168 NGKIIADFSASWCGPCNNIAPIYEDLSETYDKISFLKIDVDSQSDIATLYNITSLPTFVFFNHGAQI 368
            N  ++ +FSA WCGPC  IAP+++ +S  Y  ++F ++DVDS  ++A   +IT LPTF  F +  ++
Sbjct:   46 NKLVVVEFSAKWCGPCKTIAPVFQAMSLKYQNVTFAQVDVDSSKELAEHCDITMLPTFQMFKYTQKV 112
[Close]
BLAST of Thioredoxin vs. Ensembl Mouse
Match: Txn2 (thioredoxin 2 [Source:MGI Symbol;Acc:MGI:1929468])

HSP 1 Score: 63.929 bits (154), Expect = 3.792e-13
Identity = 27/92 (29.35%), Postives = 53/92 (57.61%), Query Frame = 3 
Query:  153 RRIDQNGKIIADFSASWCGPCNNIAPIYEDL-SETYDKISFLKIDVDSQSDIATLYNITSLPTFVFFNHGAQIHMIIG-ADVNQLKSNLEKF 422
            R ++    ++ DF A WCGPC  + P  E + ++ + K+   K+D+D  +D+A  Y ++++PT +   +G  +   +G  D +QL++ L+K 
Sbjct:   37 RVVNSETPVVVDFHAQWCGPCKILGPRLEKMVAKQHGKVVMAKVDIDDHTDLAIEYEVSAVPTVLAIKNGDVVDKFVGIKDEDQLEAFLKKL 128
[Close]
BLAST of Thioredoxin vs. Ensembl Mouse
Match: Txn2 (thioredoxin 2 [Source:MGI Symbol;Acc:MGI:1929468])

HSP 1 Score: 63.929 bits (154), Expect = 8.355e-13
Identity = 27/92 (29.35%), Postives = 53/92 (57.61%), Query Frame = 3 
Query:  153 RRIDQNGKIIADFSASWCGPCNNIAPIYEDL-SETYDKISFLKIDVDSQSDIATLYNITSLPTFVFFNHGAQIHMIIG-ADVNQLKSNLEKF 422
            R ++    ++ DF A WCGPC  + P  E + ++ + K+   K+D+D  +D+A  Y ++++PT +   +G  +   +G  D +QL++ L+K 
Sbjct:   73 RVVNSETPVVVDFHAQWCGPCKILGPRLEKMVAKQHGKVVMAKVDIDDHTDLAIEYEVSAVPTVLAIKNGDVVDKFVGIKDEDQLEAFLKKL 164
[Close]
BLAST of Thioredoxin vs. Ensembl Mouse
Match: Txn2 (thioredoxin 2 [Source:MGI Symbol;Acc:MGI:1929468])

HSP 1 Score: 63.929 bits (154), Expect = 8.355e-13
Identity = 27/92 (29.35%), Postives = 53/92 (57.61%), Query Frame = 3 
Query:  153 RRIDQNGKIIADFSASWCGPCNNIAPIYEDL-SETYDKISFLKIDVDSQSDIATLYNITSLPTFVFFNHGAQIHMIIG-ADVNQLKSNLEKF 422
            R ++    ++ DF A WCGPC  + P  E + ++ + K+   K+D+D  +D+A  Y ++++PT +   +G  +   +G  D +QL++ L+K 
Sbjct:   73 RVVNSETPVVVDFHAQWCGPCKILGPRLEKMVAKQHGKVVMAKVDIDDHTDLAIEYEVSAVPTVLAIKNGDVVDKFVGIKDEDQLEAFLKKL 164
[Close]
BLAST of Thioredoxin vs. UniProt/SwissProt
Match: sp|Q7KQL8|THIO_PLAF7 (Thioredoxin OS=Plasmodium falciparum (isolate 3D7) OX=36329 GN=PF14_0545 PE=1 SV=1)

HSP 1 Score: 99.7525 bits (247), Expect = 1.412e-26
Identity = 44/100 (44.00%), Postives = 66/100 (66.00%), Query Frame = 3 
Query:  129 ISSMNDFVRRIDQNGKIIADFSASWCGPCNNIAPIYEDLSETYDKISFLKIDVDSQSDIATLYNITSLPTFVFFNHGAQIHMIIGADVNQLKSNLEKFNA 428
            ++S  +F   I QN  +I DF A WCGPC  IAP YE+ S+TY K+ F+K+DVD  S++    NITS+PTF  + +G+ +  ++GA+ + LK  +EK+ A
Sbjct:    5 VTSQAEFDSIISQNELVIVDFFAEWCGPCKRIAPFYEECSKTYTKMVFIKVDVDEVSEVTEKENITSMPTFKVYKNGSSVDTLLGANDSALKQLIEKYAA 104
[Close]
BLAST of Thioredoxin vs. UniProt/SwissProt
Match: sp|P42115|THIO_NEUCR (Thioredoxin OS=Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) OX=367110 GN=trx PE=3 SV=1)

HSP 1 Score: 96.6709 bits (239), Expect = 4.498e-25
Identity = 46/123 (37.40%), Postives = 72/123 (58.54%), Query Frame = 3 
Query:  120 VIHISSMNDFVRRIDQNGKIIADFSASWCGPCNNIAPIYEDLSETY---DKISFLKIDVDSQSDIATLYNITSLPTFVFFNHGAQIH-----MIIGADVNQLKSNLEKFNAEIDKKISTMSES 464
            V HI+S  +F   ++    ++ADF A WCGPC  IAP+Y   ++T+   + ++F KI+VDS   +A  Y ++++PTF+FF +G Q+      MI GADVN L++  EK      +K +    S
Sbjct:    5 VKHINSAQEFANLLNTTQYVVADFYADWCGPCKAIAPMYAQFAKTFSIPNFLAFAKINVDSVQQVAQHYRVSAMPTFLFFKNGKQVAVNGSVMIQGADVNSLRAAAEKMGRLAKEKAAAAGSS 127
[Close]
BLAST of Thioredoxin vs. UniProt/SwissProt
Match: sp|Q1RQI9|THIO_MALSM (Thioredoxin (Fragment) OS=Malassezia sympodialis OX=76777 PE=1 SV=1)

HSP 1 Score: 93.5893 bits (231), Expect = 4.945e-24
Identity = 42/102 (41.18%), Postives = 67/102 (65.69%), Query Frame = 3 
Query:  129 ISSMNDFVRRIDQNGKIIADFSASWCGPCNNIAPIYEDLSET--YDKISFLKIDVDSQSDIATLYNITSLPTFVFFNHGAQIHMIIGADVNQLKSNLEKFNA 428
            ISS + F +    +  ++ DF A+WCGPC  I P++E +S+T   DK+ F K+DVD QS IA    I ++PTFVFF +G +I  ++GAD ++L++ + + +A
Sbjct:    4 ISSYDQFKQVTGGDKVVVIDFWATWCGPCKMIGPVFEKISDTPAGDKVGFYKVDVDEQSQIAQEVGIRAMPTFVFFKNGQKIDTVVGADPSKLQAAITQHSA 105
[Close]
BLAST of Thioredoxin vs. UniProt/SwissProt
Match: sp|Q0DKF1|TRH42_ORYSJ (Thioredoxin H4-2 OS=Oryza sativa subsp. japonica OX=39947 GN=Os05g0169000 PE=2 SV=1)

HSP 1 Score: 89.7373 bits (221), Expect = 2.613e-22
Identity = 42/100 (42.00%), Postives = 69/100 (69.00%), Query Frame = 3 
Query:  129 ISSMNDFVRRIDQ---NGKII-ADFSASWCGPCNNIAPIYEDLSETYDKISFLKIDVDSQSDIATLYNITSLPTFVFFNHGAQIHMIIGADVNQLKSNLE 416
            I+S  D+ R+I++   +GKI+ A+FSASWCGPC  IAPIY ++S+TY ++ FL IDVD   D ++ ++I + PTF F  +  Q+  ++GA+  +L+  ++
Sbjct:   27 ITSKEDWDRKIEEANKDGKIVVANFSASWCGPCRVIAPIYAEMSKTYPQLMFLTIDVDDLMDFSSSWDIRATPTFFFIKNEKQVDKLVGANKPELEKKVQ 126
[Close]
BLAST of Thioredoxin vs. UniProt/SwissProt
Match: sp|Q38879|TRXH2_ARATH (Thioredoxin H2 OS=Arabidopsis thaliana OX=3702 GN=TRX2 PE=2 SV=2)

HSP 1 Score: 88.9669 bits (219), Expect = 5.703e-22
Identity = 35/89 (39.33%), Postives = 56/89 (62.92%), Query Frame = 3 
Query:  162 DQNGKIIADFSASWCGPCNNIAPIYEDLSETYDKISFLKIDVDSQSDIATLYNITSLPTFVFFNHGAQIHMIIGADVNQLKSNLEKFNA 428
            + N  ++ DFSASWCGPC  I P    +++ ++ + F+K+DVD   D+A  +N+T++PTFV    G +I  IIGA  ++L+  + K  A
Sbjct:   45 ESNKLLVVDFSASWCGPCRMIEPAIHAMADKFNDVDFVKLDVDELPDVAKEFNVTAMPTFVLVKRGKEIERIIGAKKDELEKKVSKLRA 133
[Close]
BLAST of Thioredoxin vs. TrEMBL
Match: A0A061BCE4 (Thioredoxin OS=Cyberlindnera fabianii OX=36022 GN=BON22_3281 PE=3 SV=1)

HSP 1 Score: 105.531 bits (262), Expect = 5.604e-26
Identity = 44/101 (43.56%), Postives = 63/101 (62.38%), Query Frame = 3 
Query:  120 VIHISSMNDFVRRIDQNGKIIADFSASWCGPCNNIAPIYEDLSETYDKISFLKIDVDSQSDIATLYNITSLPTFVFFNHGAQIHMIIGADVNQLKSNLEKF 422
            +  IS++ +F++RID     + DF A WCGPC  IAP+ E  SE Y  + FLK+DVD   DIA  Y IT++PTFV +  G  +  I+GA  + +K  +EK+
Sbjct:   31 IPEISTLKEFLQRIDTPKLTVTDFHAQWCGPCKAIAPVIEKFSEKYTNVQFLKVDVDEAGDIAQEYGITAMPTFVLYKDGEPLGKIVGAAPDNVKKAIEKY 131
[Close]
BLAST of Thioredoxin vs. TrEMBL
Match: A0A1J1H8P7 (Thioredoxin OS=Plasmodium relictum OX=85471 GN=TRX1 PE=3 SV=1)

HSP 1 Score: 102.834 bits (255), Expect = 2.900e-25
Identity = 47/100 (47.00%), Postives = 63/100 (63.00%), Query Frame = 3 
Query:  129 ISSMNDFVRRIDQNGKIIADFSASWCGPCNNIAPIYEDLSETYDKISFLKIDVDSQSDIATLYNITSLPTFVFFNHGAQIHMIIGADVNQLKSNLEKFNA 428
            ISS  DF   I QN  +I DF A WCGPC  IAP YE+ S+ Y KI F+K+DVD  S++    NITS+PTF  + +G  +  ++GA+   LK  +EK+ A
Sbjct:    5 ISSQADFEAVISQNDIVIVDFFAEWCGPCKRIAPFYEECSKKYTKIVFVKVDVDEASEVTEKENITSMPTFKVYKNGTAVETLLGANDTALKQLIEKYAA 104
[Close]
BLAST of Thioredoxin vs. TrEMBL
Match: A0A1Y2CJT7 (Thioredoxin-domain-containing protein OS=Neocallimastix californiae OX=1754190 GN=LY90DRAFT_457404 PE=4 SV=1)

HSP 1 Score: 105.145 bits (261), Expect = 3.003e-25
Identity = 42/103 (40.78%), Postives = 71/103 (68.93%), Query Frame = 3 
Query:  114 MPVIHISSMNDFVRRIDQNGKIIADFSASWCGPCNNIAPIYEDLSETYDKISFLKIDVDSQSDIATLYNITSLPTFVFFNHGAQIHMIIGADVNQLKSNLEKF 422
            MP+IH+SS  ++ + + Q    + DF A WCGPC  IAP +E+LS TY   +FLK+++D  + +A+  +++S+PTF+F+  G  +H I GA+V +L+S ++K+
Sbjct:    1 MPIIHVSSEVEYNKYVSQGKLTVVDFFADWCGPCKAIAPRFENLSNTYRNANFLKVNIDEMNSLASGLSVSSIPTFIFYKSGKTLHRITGANVAELESTIKKY 103
[Close]
BLAST of Thioredoxin vs. TrEMBL
Match: A0A367JRN7 (Thioredoxin OS=Rhizopus stolonifer OX=4846 GN=TRX2_2 PE=3 SV=1)

HSP 1 Score: 102.449 bits (254), Expect = 5.045e-25
Identity = 41/104 (39.42%), Postives = 63/104 (60.58%), Query Frame = 3 
Query:  114 MPVIHISSMNDFVRRIDQNGKIIADFSASWCGPCNNIAPIYEDLSETYDKISFLKIDVDSQSDIATLYNITSLPTFVFFNHGAQIHMIIGADVNQLKSNLEKFN 425
            MP+I I S   F + I  N  I+ DF A WCGPC  IAP  E  + TY  + FLK+DVD+  + A  Y IT++PT +FF  G ++  ++GA++ +++  +E+  
Sbjct:    1 MPIIEIGSHETFQKVIQHNKLIVVDFYAVWCGPCKAIAPRMESFAATYSDVVFLKVDVDTLKETAAQYQITAMPTILFFKQGQKLGQVVGANIKEIQDKIEQLR 104
[Close]
BLAST of Thioredoxin vs. TrEMBL
Match: A0A1J1GQR9 (Thioredoxin OS=Plasmodium gallinaceum OX=5849 GN=PGAL8A_00216500 PE=3 SV=1)

HSP 1 Score: 102.064 bits (253), Expect = 6.986e-25
Identity = 47/100 (47.00%), Postives = 61/100 (61.00%), Query Frame = 3 
Query:  129 ISSMNDFVRRIDQNGKIIADFSASWCGPCNNIAPIYEDLSETYDKISFLKIDVDSQSDIATLYNITSLPTFVFFNHGAQIHMIIGADVNQLKSNLEKFNA 428
            ISS  DF   I QN  +I DF A WCGPC  IAP YE+ SE Y  I F+K+DVD  S++    NITS+PTF  +  G  +  ++GA+   LK  +EK+ A
Sbjct:    5 ISSQADFEDIISQNDVVIVDFFAEWCGPCKRIAPFYEECSEKYKNIVFIKVDVDEASEVTEKENITSMPTFKVYKKGVSVETLLGANDTALKQLIEKYAA 104
[Close]
BLAST of Thioredoxin vs. Ensembl Cavefish
Match: txn (thioredoxin-like [Source:NCBI gene;Acc:103039731])

HSP 1 Score: 79.337 bits (194), Expect = 1.893e-19
Identity = 40/106 (37.74%), Postives = 60/106 (56.60%), Query Frame = 3 
Query:  114 MPVIHISSMNDFVRRIDQNGK--IIADFSASWCGPCNNIAPIYEDLSETYD--KISFLKIDVDSQSDIATLYNITSLPTFVFFNHGAQIHMIIGADVNQLKSNLEK 419
            MPVI I   + F + +   G   ++ DF+A+WCGPC  IAP Y++LS+      + FLK+DVD   D+A    I  +PTF F+ +G +I    G + ++L   L K
Sbjct:    1 MPVIEIEDKDSFDKALRDAGSKLVVVDFTATWCGPCKMIAPYYKELSDNPQNSNVVFLKVDVDDAQDVAAHCEIKCMPTFHFYKNGKKIDEFSGGNRDKLVEILNK 106
[Close]
BLAST of Thioredoxin vs. Ensembl Cavefish
Match: zgc:56493 (thioredoxin-like [Source:NCBI gene;Acc:103040975])

HSP 1 Score: 75.8702 bits (185), Expect = 4.431e-18
Identity = 36/100 (36.00%), Postives = 58/100 (58.00%), Query Frame = 3 
Query:  120 VIHISSMNDFVRRIDQNGK--IIADFSASWCGPCNNIAPIYEDLSETYD--KISFLKIDVDSQSDIATLYNITSLPTFVFFNHGAQIHMIIGADVNQLKS 407
            +I I     F + + + G   ++ DF+A+WCGPC +IAP Y+ LSE  D   + FLK+DVD   D+A    I  +PTF F+ +G ++    G++  +L+ 
Sbjct:    2 IIVIEDQEGFDKALAEAGDKLVVVDFTATWCGPCQSIAPFYKGLSEKPDNGNVVFLKVDVDDAQDVAQSCEIKCMPTFHFYKNGKKVDEFSGSNQAKLEE 101
[Close]
BLAST of Thioredoxin vs. Ensembl Cavefish
Match: txn2 (thioredoxin 2 [Source:NCBI gene;Acc:103028978])

HSP 1 Score: 64.3142 bits (155), Expect = 4.505e-13
Identity = 30/102 (29.41%), Postives = 57/102 (55.88%), Query Frame = 3 
Query:  126 HISSMNDFVRR-IDQNGKIIADFSASWCGPCNNIAPIYED-LSETYDKISFLKIDVDSQSDIATLYNITSLPTFVFFNHGAQIHMIIG-ADVNQLKSNLEKF 422
            ++   +DF  R I+ +  ++ DF A WCGPC  + P  E  +++   +++  K+D+D  +D+A  Y ++++PT +    G  I   +G  D +QL S ++K 
Sbjct:   62 NVQDQDDFTERVINSDLPVVIDFHAQWCGPCKILGPRLEKAIAKQKGRVTMAKVDIDEHTDLAIEYGVSAVPTVIAMRGGDVIDQFVGIKDEDQLDSFVKKL 163
[Close]
BLAST of Thioredoxin vs. Ensembl Cavefish
Match: txnl1 (thioredoxin like 1 [Source:NCBI gene;Acc:103021638])

HSP 1 Score: 58.5362 bits (140), Expect = 2.422e-10
Identity = 26/80 (32.50%), Postives = 45/80 (56.25%), Query Frame = 3 
Query:  180 IADFSASWCGPCNNIAPIYEDLSETYDKISFLKIDVDSQSDIATLYNITSLPTFVFFNHGAQIHMIIGADVNQLKSNLEK 419
            +  F+ + C PC  IAP +  LS  Y ++ FL++DV      A   NI++ PTF+FF +  ++    GAD + L+  +++
Sbjct:   26 VVKFTMAGCRPCLRIAPAFNMLSSKYPQVVFLEVDVHVCQGTAAANNISATPTFLFFRNKVRVDQYQGADASGLEDKIKQ 105
[Close]
BLAST of Thioredoxin vs. Ensembl Cavefish
Match: txnl1 (thioredoxin like 1 [Source:NCBI gene;Acc:103021638])

HSP 1 Score: 58.5362 bits (140), Expect = 2.526e-10
Identity = 26/80 (32.50%), Postives = 45/80 (56.25%), Query Frame = 3 
Query:  180 IADFSASWCGPCNNIAPIYEDLSETYDKISFLKIDVDSQSDIATLYNITSLPTFVFFNHGAQIHMIIGADVNQLKSNLEK 419
            +  F+ + C PC  IAP +  LS  Y ++ FL++DV      A   NI++ PTF+FF +  ++    GAD + L+  +++
Sbjct:   26 VVKFTMAGCRPCLRIAPAFNMLSSKYPQVVFLEVDVHVCQGTAAANNISATPTFLFFRNKVRVDQYQGADASGLEDKIKQ 105
[Close]
BLAST of Thioredoxin vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007779.1 (pep scaffold:Pmarinus_7.0:GL477155:15795:22678:-1 gene:ENSPMAG00000007027.1 transcript:ENSPMAT00000007779.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 70.8626 bits (172), Expect = 6.924e-17
Identity = 35/106 (33.02%), Postives = 57/106 (53.77%), Query Frame = 3 
Query:  120 VIHISSMNDF--VRRIDQNGKIIADFSASWCGPCNNIAPIYEDLSET--YDKISFLKIDVDSQSDIATLYNITSLPTFVFFNHGAQIHMIIGADVNQLKSNLEKFN 425
              + SS +DF  ++    +  II  F+A WCGPC  I   Y  ++E   Y+ + F ++DVD  +D+ + + I  +PTFVFF  G Q+  + G     L+  +EK+ 
Sbjct:    2 TFYFSSQSDFDEIKGCAGSRLIILFFTAKWCGPCQQIKEPYHTMAEKEEYNAV-FCEVDVDEAADLLSSFGINCMPTFVFFKDGIQLEKLEGGSQGNLRKRIEKYE 106
[Close]
BLAST of Thioredoxin vs. Ensembl Sea Lamprey
Match: ENSPMAT00000009652.1 (pep scaffold:Pmarinus_7.0:GL478563:4231:10899:-1 gene:ENSPMAG00000008707.1 transcript:ENSPMAT00000009652.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 68.5514 bits (166), Expect = 4.924e-16
Identity = 34/93 (36.56%), Postives = 59/93 (63.44%), Query Frame = 3 
Query:  144 DFVRRIDQNGK--IIADFSASWCGPCNNIAPIYEDLSETYDKISFLKIDVDSQSDIATLYNITSLPTFVFFNHGAQIHMIIGADVNQLKSNLE 416
            ++ + ++QN    ++ DFSA+WCGPC  I+PI+   +  Y  + F  +DVD   DIA L NI ++PTF+FF +  ++  ++GA+ + L+  L+
Sbjct:   10 EYKQVLEQNKHKLVVIDFSATWCGPCKIISPIFHAFANEYHNVVFCVVDVDDAPDIAELCNIKAMPTFIFFKNNEKVGEVMGANKDHLEKTLK 102
[Close]
BLAST of Thioredoxin vs. Ensembl Sea Lamprey
Match: txn2 (thioredoxin 2 [Source:ZFIN;Acc:ZDB-GENE-040426-1795])

HSP 1 Score: 70.4774 bits (171), Expect = 5.650e-16
Identity = 31/102 (30.39%), Postives = 59/102 (57.84%), Query Frame = 3 
Query:  126 HISSMNDFVRRI-DQNGKIIADFSASWCGPCNNIAPIYEDL-SETYDKISFLKIDVDSQSDIATLYNITSLPTFVFFNHGAQIHMIIGA-DVNQLKSNLEKF 422
            H+  ++DF  R+ + +  ++ DF A WCGPC  + P  E L ++   K+   K+D+D  +D+A  Y ++++PT +   +G+ +   +G  D +QL+  L+K 
Sbjct:   71 HVQDVDDFTERVVNSDTPVVVDFHAQWCGPCKILGPRLEKLVAKQSGKVLMAKVDIDDHTDLAVEYGVSAVPTVLAMRNGSVVDKFVGVRDEDQLEVFLKKL 172
[Close]
BLAST of Thioredoxin vs. Ensembl Sea Lamprey
Match: glrx3 (glutaredoxin 3 [Source:NCBI gene;Acc:449777])

HSP 1 Score: 56.6102 bits (135), Expect = 2.287e-10
Identity = 23/97 (23.71%), Postives = 51/97 (52.58%), Query Frame = 3 
Query:  180 IADFSASWCGPCNNIAPIYEDLSETYDKISFLKIDVDSQSDIATLYNITSLPTFVFFNHGAQIHMIIGADVNQLKSNLEKFNAEIDKKISTMSESVK 470
            +  F A+W   C  +  + E+L+  +  +SF+K++ ++  ++A  +N+ ++PTF+FF  G  +  + GA   +L   +++  A +     T +   K
Sbjct:   11 LVHFWATWAPQCAQMNDVMEELATEHPAVSFVKLEAEAVPELALKHNVKAVPTFIFFKAGQPVERLDGAHAPELVKKVQQLVASLPHATPTTTAVAK 107
[Close]
BLAST of Thioredoxin vs. Ensembl Sea Lamprey
Match: txndc5 (thioredoxin domain containing 5 [Source:ZFIN;Acc:ZDB-GENE-040426-1951])

HSP 1 Score: 51.6026 bits (122), Expect = 1.323e-8
Identity = 21/71 (29.58%), Postives = 38/71 (53.52%), Query Frame = 3 
Query:  168 NGKIIADFSASWCGPCNNIAPIYEDLSET----YDKISFLKIDVDSQSDIATLYNITSLPTFVFFNHGAQI 368
            +G     F A WCG C N+AP +EDL++       K++  K+D  S++ + +  ++   PT + +  G Q+
Sbjct:  311 DGITFVKFYAPWCGHCKNLAPTWEDLAKKEFSGLSKVTIAKVDCTSEAQLCSKQHVRGYPTLLLYVGGKQV 381

HSP 2 Score: 49.2914 bits (116), Expect = 9.819e-8
Identity = 25/94 (26.60%), Postives = 42/94 (44.68%), Query Frame = 3 
Query:  189 FSASWCGPCNNIAPIYEDLSETYD---KISFLKIDVDSQSDIATLYNITSLPTFVFFNHGAQIHMIIGADVNQLKSNLEKFNAEIDKKISTMSE 461
            F A WCG C  + P +E L+ T++   K+   K+D  +  DI     +   PT ++F  G ++    G      K +L+     +D +I    E
Sbjct:  193 FFAPWCGHCKALIPAWEQLASTFEYSGKVKIAKVDCTAHQDICNENQVRGYPTLLWFKDGEKVDQYRG------KRDLDSLKVFVDTQIQIEPE 280
[Close]
BLAST of Thioredoxin vs. Ensembl Yeast
Match: TRX1 (Cytoplasmic thioredoxin isoenzyme; part of thioredoxin system which protects cells against oxidative and reductive stress; forms LMA1 complex with Pbi2p; acts as a cofactor for Tsa1p; required for ER-Golgi transport and vacuole inheritance; with Trx2p, facilitates mitochondrial import of small Tims Tim9p, Tim10p, Tim13p by maintaining them in reduced form; abundance increases iunder DNA replication stress; TRX1 has a paralog, TRX2, that arose from the whole genome duplication [Source:SGD;Acc:S000004033])

HSP 1 Score: 82.8037 bits (203), Expect = 8.319e-22
Identity = 33/98 (33.67%), Postives = 57/98 (58.16%), Query Frame = 3 
Query:  120 VIHISSMNDFVRRIDQNGKIIADFSASWCGPCNNIAPIYEDLSETYDKISFLKIDVDSQSDIATLYNITSLPTFVFFNHGAQIHMIIGADVNQLKSNL 413
            V    + ++F   I Q+  ++ DF A+WCGPC  IAP+ E  SE Y +  F K+DVD   D+A    ++++PT + F +G ++  ++GA+   +K  +
Sbjct:    2 VTQFKTASEFDSAIAQDKLVVVDFYATWCGPCKMIAPMIEKFSEQYPQADFYKLDVDELGDVAQKNEVSAMPTLLLFKNGKEVAKVVGANPAAIKQAI 99
[Close]
BLAST of Thioredoxin vs. Ensembl Yeast
Match: TRX2 (Cytoplasmic thioredoxin isoenzyme; part of thioredoxin system which protects cells against oxidative and reductive stress; forms LMA1 complex with Pbi2p; acts as a cofactor for Tsa1p; required for ER-Golgi transport and vacuole inheritance; with Trx1p, facilitates mitochondrial import of small Tims Tim9p, Tim10p, Tim13p by maintaining them in reduced form; abundance increases under DNA replication stress; TRX2 has a paralog, TRX1, that arose from the whole genome duplication [Source:SGD;Acc:S000003441])

HSP 1 Score: 80.8777 bits (198), Expect = 5.878e-21
Identity = 33/99 (33.33%), Postives = 58/99 (58.59%), Query Frame = 3 
Query:  120 VIHISSMNDFVRRIDQNGK-IIADFSASWCGPCNNIAPIYEDLSETYDKISFLKIDVDSQSDIATLYNITSLPTFVFFNHGAQIHMIIGADVNQLKSNL 413
            V  + S +++   +    K ++ DF A+WCGPC  IAP+ E  +E Y   +F K+DVD  SD+A    ++S+PT +F+  G ++  ++GA+   +K  +
Sbjct:    2 VTQLKSASEYDSALASGDKLVVVDFFATWCGPCKMIAPMIEKFAEQYSDAAFYKLDVDEVSDVAQKAEVSSMPTLIFYKGGKEVTRVVGANPAAIKQAI 100
[Close]
BLAST of Thioredoxin vs. Ensembl Yeast
Match: TRX3 (Mitochondrial thioredoxin; highly conserved oxidoreductase required to maintain the redox homeostasis of the cell, forms the mitochondrial thioredoxin system with Trr2p, redox state is maintained by both Trr2p and Glr1p [Source:SGD;Acc:S000000679])

HSP 1 Score: 81.2629 bits (199), Expect = 6.486e-21
Identity = 36/99 (36.36%), Postives = 56/99 (56.57%), Query Frame = 3 
Query:  120 VIHISSMNDFVRRIDQNGKIIADFSASWCGPCNNIAPIYEDLSETYDKISFLKIDVDSQSDIATLYNITSLPTFVFFNHGAQIHMIIGADVNQLKSNLE 416
            +  ++++ +F   I QN K++ DF A+WCGPC  + P    L + Y  + F+K DVD   DIA    +T++PTFV    G  I  IIGA+   L+  ++
Sbjct:   27 ITKLTNLTEFRNLIKQNDKLVIDFYATWCGPCKMMQPHLTKLIQAYPDVRFVKCDVDESPDIAKECEVTAMPTFVLGKDGQLIGKIIGANPTALEKGIK 125
[Close]
BLAST of Thioredoxin vs. Ensembl Yeast
Match: GRX4 (Glutathione-dependent oxidoreductase; hydroperoxide and superoxide-radical responsive; monothiol glutaredoxin subfamily member along with Grx3p and Grx5p; protects cells from oxidative damage; with Grx3p, binds to Aft1p in iron-replete conditions, promoting its dissociation from promoters; mutant has increased aneuploidy tolerance; transcription regulated by Yap5p; GRX4 has a paralog, GRX3, that arose from the whole genome duplication [Source:SGD;Acc:S000000976])

HSP 1 Score: 62.003 bits (149), Expect = 1.334e-12
Identity = 33/106 (31.13%), Postives = 52/106 (49.06%), Query Frame = 3 
Query:  114 MPVIHISSMNDFVRRIDQNGK---IIADFSASWCGPCNNIAPIYEDLSET--YDKISFLKIDVDSQSDIATLYNITSLPTFVFFNHGAQIHMIIGADVNQLKSNLE 416
            M V+ I S + F +    N     I+  F A W  PC  ++ + E +SE    + + FL ID D   +I+ L+ I ++P FVF  +G  +  I  AD  +   +LE
Sbjct:    1 MTVVEIKSQDQFTQLTTTNAANKLIVLYFKAQWADPCKTMSQVLEAVSEKVRQEDVRFLSIDADEHPEISDLFEIAAVPYFVFIQNGTIVKEISAADPKEFVKSLE 106
[Close]
BLAST of Thioredoxin vs. Ensembl Yeast
Match: GRX3 (Glutathione-dependent oxidoreductase; hydroperoxide and superoxide-radical responsive; monothiol glutaredoxin subfamily member along with Grx4p and Grx5p; protects cells from oxidative damage; with Grx4p, binds to Aft1p in iron-replete conditions, promoting its dissociation from promoters; evidence exists indicating that the translation start site is not Met1 as currently annotated, but rather Met36; GRX3 has a paralog, GRX4, that arose from the whole genome duplication [Source:SGD;Acc:S000002505])

HSP 1 Score: 56.9954 bits (136), Expect = 6.901e-11
Identity = 33/106 (31.13%), Postives = 52/106 (49.06%), Query Frame = 3 
Query:  114 MPVIHISSMNDFVRRIDQNGK---IIADFSASWCGPCNNIAPIYEDLSE--TYDKISFLKIDVDSQSDIATLYNITSLPTFVFFNHGAQIHMIIGADVNQLKSNLE 416
            MPVI I+    F            I+  F  SW  PC  +  ++E +S   +   +SFL ID D  S+I+ L+ I+++P F+  + G  +  + GAD  +  S LE
Sbjct:    1 MPVIEINDQEQFTYLTTTAAGDKLIVLYFHTSWAEPCKALKQVFEAISNEPSNSNVSFLSIDADENSEISELFEISAVPYFIIIHKGTILKELSGADPKEYVSLLE 106
[Close]
BLAST of Thioredoxin vs. Ensembl Nematostella
Match: EDO41852 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S3A4])

HSP 1 Score: 88.9669 bits (219), Expect = 6.440e-22
Identity = 37/82 (45.12%), Postives = 56/82 (68.29%), Query Frame = 3 
Query:  177 IIADFSASWCGPCNNIAPIYEDLSETYDKISFLKIDVDSQSDIATLYNITSLPTFVFFNHGAQIHMIIGADVNQLKSNLEKF 422
            ++ADF+ASWCGPC +IAP+Y  LSE Y +  FLKIDVD   ++A    +T++PTF FF +  ++  + GAD   L+  ++K+
Sbjct:   30 VVADFTASWCGPCKSIAPVYSGLSEKYKQAVFLKIDVDVCQELAAKQGVTAMPTFQFFKNKVKVDEVRGADPKALEDAIKKW 111
[Close]
BLAST of Thioredoxin vs. Ensembl Nematostella
Match: EDO46139 (Thioredoxin [Source:UniProtKB/TrEMBL;Acc:A7RQN2])

HSP 1 Score: 80.1073 bits (196), Expect = 3.387e-20
Identity = 32/102 (31.37%), Postives = 60/102 (58.82%), Query Frame = 3 
Query:  120 VIHISSMNDFVRRIDQNGKIIADFSASWCGPCNNIAPIYEDLSETYDKISFLKIDVDSQSDIATLYNITSLPTFVFFNHGAQIHMIIGADVNQLKSNLEKFN 425
            ++ +++  +F + +  N     DF+A+WCGPC  I P +E++++ +  +   K+DVD  S+ A    IT++PTF F+ +G  +  ++GA  ++LK    K N
Sbjct:    1 MLQLNTKGEFDKFLKDNEVAAIDFTATWCGPCRMIGPKFEEMAKEFKGVKCAKVDVDVNSETAESEGITAMPTFRFYKNGEMVDEVVGASESKLKELFAKHN 102
[Close]
BLAST of Thioredoxin vs. Ensembl Nematostella
Match: EDO33372 (Thioredoxin [Source:UniProtKB/TrEMBL;Acc:A7SSF5])

HSP 1 Score: 73.1738 bits (178), Expect = 1.530e-17
Identity = 34/91 (37.36%), Postives = 57/91 (62.64%), Query Frame = 3 
Query:  147 FVRRIDQNGK--IIADFSASWCGPCNNIAPIYEDLSETYDKISFLKIDVDSQSDIATLYNITSLPTFVFFNHGAQIHMIIGADVNQLKSNL 413
            F   I++ G   ++ DF+A+WCGPC +IAP++ +LS  +  + FLK+DVD     A    I ++PTF F+++ A+I  + GAD   L++ +
Sbjct:   16 FSVEIERAGSRLVVIDFTATWCGPCKSIAPVFTNLSMKFMDVVFLKVDVDQCQLTAESCGIRAMPTFHFYHNKAKIDELRGADPGALENKI 106
[Close]
BLAST of Thioredoxin vs. Ensembl Nematostella
Match: EDO45413 (Thioredoxin [Source:UniProtKB/TrEMBL;Acc:A7RT76])

HSP 1 Score: 68.9366 bits (167), Expect = 1.024e-15
Identity = 29/83 (34.94%), Postives = 53/83 (63.86%), Query Frame = 3 
Query:  177 IIADFSASWCGPCNNIAPIYEDLS-ETYDKISFLKIDVDSQSDIATLYNITSLPTFVFFNHGAQIHMIIGADVNQLKSNLEKF 422
            ++ DF A WCGPC  I P ++ ++ E +  + F KIDVD   +++    IT++PTFVF+ +G ++  ++GA+  +L+  + K+
Sbjct:   33 VVIDFYAEWCGPCRQIKPKFKKMALEEFKDVFFAKIDVDELEELSEDEQITAMPTFVFYKNGQKLEKLVGANEVKLRELILKY 115
[Close]
BLAST of Thioredoxin vs. Ensembl Nematostella
Match: EDO28362 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T6P3])

HSP 1 Score: 63.5438 bits (153), Expect = 6.626e-14
Identity = 31/76 (40.79%), Postives = 45/76 (59.21%), Query Frame = 3 
Query:  168 NGKI--IADFSASWCGPCNNIAPIYEDLSETY-DKISFLKIDVDSQSDIATLYNITSLPTFVFFNHGAQIHMIIGA 386
             GK+  I DF A WCGPC  +API E LSE Y +KI+  KID +++ +++  + I S+P+ +F        M  GA
Sbjct:    6 EGKVPAIIDFYADWCGPCKMLAPILEQLSEEYGEKINIYKIDTEAEQELSAAFGIRSIPSMLFCPMDEDPQMANGA 81
[Close]
BLAST of Thioredoxin vs. Ensembl Medaka
Match: ENSORLT00000009496.2 (thioredoxin [Source:NCBI gene;Acc:101173415])

HSP 1 Score: 80.4925 bits (197), Expect = 6.354e-20
Identity = 37/103 (35.92%), Postives = 64/103 (62.14%), Query Frame = 3 
Query:  120 VIHISSMNDFVRRIDQNGK--IIADFSASWCGPCNNIAPIYEDLSETYD--KISFLKIDVDSQSDIATLYNITSLPTFVFFNHGAQIHMIIGADVNQLKSNLE 416
            V  ++ + +F + ++  G   ++ DF+ASWCGPC  IAP+Y+ +SE+ D   + FLK+DVD ++D++    I  +PTF F+  G ++    GA+V  L+  L+
Sbjct:    2 VREVADLAEFKKILEDAGDKLVVVDFTASWCGPCKQIAPLYKQMSESDDNKNVVFLKVDVD-EADVSVFCEIKCMPTFHFYKGGKKVDEFSGANVATLEEKLK 103
[Close]
BLAST of Thioredoxin vs. Ensembl Medaka
Match: txn2 (thioredoxin 2 [Source:NCBI gene;Acc:101164313])

HSP 1 Score: 58.9214 bits (141), Expect = 4.511e-11
Identity = 27/100 (27.00%), Postives = 53/100 (53.00%), Query Frame = 3 
Query:  129 ISSMNDFVRRI-DQNGKIIADFSASWCGPCNNIAPIYED-LSETYDKISFLKIDVDSQSDIATLYNITSLPTFVFFNHGAQIHMIIG-ADVNQLKSNLEK 419
            +    DF  R+ +    ++ DF A WCGPC  + P  E  +++   +++  K+D+D  +D+A  Y ++++PT +    G  +   +G  D ++L S + K
Sbjct:   69 VQDTEDFTERVVNSQLPVLVDFHAQWCGPCKILGPRLEKAVAKQKGRVAMAKVDIDEHTDLAIEYGVSAVPTVIAMRGGDVVDHFVGIKDDDELDSFVSK 168
[Close]
BLAST of Thioredoxin vs. Ensembl Medaka
Match: txn2 (thioredoxin 2 [Source:NCBI gene;Acc:101164313])

HSP 1 Score: 58.9214 bits (141), Expect = 4.714e-11
Identity = 27/100 (27.00%), Postives = 53/100 (53.00%), Query Frame = 3 
Query:  129 ISSMNDFVRRI-DQNGKIIADFSASWCGPCNNIAPIYED-LSETYDKISFLKIDVDSQSDIATLYNITSLPTFVFFNHGAQIHMIIG-ADVNQLKSNLEK 419
            +    DF  R+ +    ++ DF A WCGPC  + P  E  +++   +++  K+D+D  +D+A  Y ++++PT +    G  +   +G  D ++L S + K
Sbjct:   73 VQDTEDFTERVVNSQLPVLVDFHAQWCGPCKILGPRLEKAVAKQKGRVAMAKVDIDEHTDLAIEYGVSAVPTVIAMRGGDVVDHFVGIKDDDELDSFVSK 172
[Close]
BLAST of Thioredoxin vs. Ensembl Medaka
Match: glrx3 (glutaredoxin 3 [Source:NCBI gene;Acc:449777])

HSP 1 Score: 59.3066 bits (142), Expect = 1.475e-10
Identity = 26/101 (25.74%), Postives = 57/101 (56.44%), Query Frame = 3 
Query:  120 VIHISSMNDFVRRIDQNGKIIA--DFSASWCGPCNNIAPIYEDLSETYDKISFLKIDVDSQSDIATLYNITSLPTFVFFNHGAQIHMIIGADVNQLKSNLE 416
            V+  +S   F   + + GK +A   F A+W   C ++  +  +L++ +   +F+K++ ++  D++  Y+I+S+PTF+FF  G ++  + GA   +L   ++
Sbjct:   11 VLEATSRQQFEDFLAKAGKNLAVVHFQAAWAPQCGDMNEVMAELAKAHAHATFVKLEAEAVPDVSEKYDISSVPTFIFFKGGEKVDRLDGAHAAELTKKVQ 111
[Close]
BLAST of Thioredoxin vs. Ensembl Medaka
Match: txnl1 (thioredoxin like 1 [Source:NCBI gene;Acc:101158293])

HSP 1 Score: 57.7658 bits (138), Expect = 3.816e-10
Identity = 30/99 (30.30%), Postives = 50/99 (50.51%), Query Frame = 3 
Query:  129 ISSMNDFVRRIDQNGK--IIADFSASWCGPCNNIAPIYEDLSETYDKISFLKIDVDSQSDIATLYNITSLPTFVFFNHGAQIHMIIGADVNQLKSNLEK 419
            I S  DF   +   G   ++  F+ + C PC  I+P +  LS  Y  + FL++DV      A   NI++ PTF+FF +  ++    GAD   L+  +++
Sbjct:    7 IGSDPDFQPELAAAGSRLVVVKFTMAGCRPCVRISPAFNALSNKYPHVVFLEVDVHVCQATAAANNISATPTFLFFRNRVRVDQYQGADAAGLEEKIKQ 105
[Close]
BLAST of Thioredoxin vs. Planmine SMEST
Match: SMESG000023196.1 (SMESG000023196.1)

HSP 1 Score: 262.307 bits (669), Expect = 1.885e-91
Identity = 127/127 (100.00%), Postives = 127/127 (100.00%), Query Frame = 3 
Query:  114 MPVIHISSMNDFVRRIDQNGKIIADFSASWCGPCNNIAPIYEDLSETYDKISFLKIDVDSQSDIATLYNITSLPTFVFFNHGAQIHMIIGADVNQLKSNLEKFNAEIDKKISTMSESVKSKRCCLLI 494
            MPVIHISSMNDFVRRIDQNGKIIADFSASWCGPCNNIAPIYEDLSETYDKISFLKIDVDSQSDIATLYNITSLPTFVFFNHGAQIHMIIGADVNQLKSNLEKFNAEIDKKISTMSESVKSKRCCLLI
Sbjct:    1 MPVIHISSMNDFVRRIDQNGKIIADFSASWCGPCNNIAPIYEDLSETYDKISFLKIDVDSQSDIATLYNITSLPTFVFFNHGAQIHMIIGADVNQLKSNLEKFNAEIDKKISTMSESVKSKRCCLLI 127
[Close]
BLAST of Thioredoxin vs. Planmine SMEST
Match: SMESG000023196.1 (SMESG000023196.1)

HSP 1 Score: 246.128 bits (627), Expect = 3.729e-85
Identity = 119/119 (100.00%), Postives = 119/119 (100.00%), Query Frame = 3 
Query:  138 MNDFVRRIDQNGKIIADFSASWCGPCNNIAPIYEDLSETYDKISFLKIDVDSQSDIATLYNITSLPTFVFFNHGAQIHMIIGADVNQLKSNLEKFNAEIDKKISTMSESVKSKRCCLLI 494
            MNDFVRRIDQNGKIIADFSASWCGPCNNIAPIYEDLSETYDKISFLKIDVDSQSDIATLYNITSLPTFVFFNHGAQIHMIIGADVNQLKSNLEKFNAEIDKKISTMSESVKSKRCCLLI
Sbjct:    1 MNDFVRRIDQNGKIIADFSASWCGPCNNIAPIYEDLSETYDKISFLKIDVDSQSDIATLYNITSLPTFVFFNHGAQIHMIIGADVNQLKSNLEKFNAEIDKKISTMSESVKSKRCCLLI 119
[Close]
BLAST of Thioredoxin vs. Planmine SMEST
Match: SMESG000023196.1 (SMESG000023196.1)

HSP 1 Score: 226.483 bits (576), Expect = 2.545e-77
Identity = 109/111 (98.20%), Postives = 110/111 (99.10%), Query Frame = 3 
Query:  114 MPVIHISSMNDFVRRIDQNGKIIADFSASWCGPCNNIAPIYEDLSETYDKISFLKIDVDSQSDIATLYNITSLPTFVFFNHGAQIHMIIGADVNQLKSNLEKFNAEIDKKI 446
            MPVIHISSMNDFVRRIDQNGKIIADFSASWCGPCNNIAPIYEDLSETYDKISFLKIDVDSQSDIATLYNITSLPTFVFFNHGAQIHMIIGADVNQLKSNLEKFNAEIDK +
Sbjct:    1 MPVIHISSMNDFVRRIDQNGKIIADFSASWCGPCNNIAPIYEDLSETYDKISFLKIDVDSQSDIATLYNITSLPTFVFFNHGAQIHMIIGADVNQLKSNLEKFNAEIDKHL 111
[Close]
BLAST of Thioredoxin vs. Planmine SMEST
Match: SMESG000023196.1 (SMESG000023196.1)

HSP 1 Score: 209.92 bits (533), Expect = 5.026e-71
Identity = 101/103 (98.06%), Postives = 102/103 (99.03%), Query Frame = 3 
Query:  138 MNDFVRRIDQNGKIIADFSASWCGPCNNIAPIYEDLSETYDKISFLKIDVDSQSDIATLYNITSLPTFVFFNHGAQIHMIIGADVNQLKSNLEKFNAEIDKKI 446
            MNDFVRRIDQNGKIIADFSASWCGPCNNIAPIYEDLSETYDKISFLKIDVDSQSDIATLYNITSLPTFVFFNHGAQIHMIIGADVNQLKSNLEKFNAEIDK +
Sbjct:    1 MNDFVRRIDQNGKIIADFSASWCGPCNNIAPIYEDLSETYDKISFLKIDVDSQSDIATLYNITSLPTFVFFNHGAQIHMIIGADVNQLKSNLEKFNAEIDKHL 103
[Close]
BLAST of Thioredoxin vs. Planmine SMEST
Match: SMESG000039109.1 (SMESG000039109.1)

HSP 1 Score: 75.8702 bits (185), Expect = 2.981e-18
Identity = 36/100 (36.00%), Postives = 60/100 (60.00%), Query Frame = 3 
Query:  129 ISSMNDFVRRIDQNGK--IIADFSASWCGPCNNIAPIYEDLSE--TYDKISFLKIDVDSQSDIATLYNITSLPTFVFFNHGAQIHMIIGADVNQLKSNLE 416
            + S  +F   ID NG   +I DF A WCGPC  ++P ++  ++   +  + FLK+DVD   ++A  Y+I+ +PTF+FF +G +I    GA+ ++L   L+
Sbjct:    5 VESEEEFQDFIDGNGSKLVIVDFWAEWCGPCRLMSPAFDKFAKDSQFKDVIFLKVDVDELGELAEKYDISCMPTFIFFRNGEKIDEFSGANKDKLLEMLK 104
The following BLAST results are available for this feature:
BLAST of Thioredoxin vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
TXN8.338e-2137.00thioredoxin [Source:HGNC Symbol;Acc:HGNC:12435][more]
TXNDC25.963e-1333.65thioredoxin domain containing 2 [Source:HGNC Symbo... [more]
TXNDC26.334e-1333.65thioredoxin domain containing 2 [Source:HGNC Symbo... [more]
TXN21.085e-1229.35thioredoxin 2 [Source:HGNC Symbol;Acc:HGNC:17772][more]
TXN21.085e-1229.35thioredoxin 2 [Source:HGNC Symbol;Acc:HGNC:17772][more]
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BLAST of Thioredoxin vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
trx-18.659e-2437.96Thioredoxin-1 [Source:UniProtKB/Swiss-Prot;Acc:Q0... [more]
Y55F3AR.29.935e-2443.81pep chromosome:WBcel235:IV:1094545:1096723:1 gene:... [more]
png-17.226e-2336.07Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagin... [more]
trx-12.158e-2039.00Thioredoxin-1 [Source:UniProtKB/Swiss-Prot;Acc:Q0... [more]
txl-16.097e-2037.14ThioredoXin-Like; Thioredoxin-like protein; Thiore... [more]
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BLAST of Thioredoxin vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Txl3.850e-2139.42gene:FBgn0035631 transcript:FBtr0077098[more]
Trx-27.343e-1944.44gene:FBgn0040070 transcript:FBtr0079840[more]
Trx-27.343e-1944.44gene:FBgn0040070 transcript:FBtr0079839[more]
TrxT2.013e-1840.24gene:FBgn0029752 transcript:FBtr0070755[more]
TrxT2.013e-1840.24gene:FBgn0029752 transcript:FBtr0340478[more]
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BLAST of Thioredoxin vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
TXN1.101e-1738.55zgc:56493 [Source:ZFIN;Acc:ZDB-GENE-030131-8581][more]
txn6.702e-1738.37thioredoxin [Source:ZFIN;Acc:ZDB-GENE-040718-162][more]
txn7.398e-1738.37thioredoxin [Source:ZFIN;Acc:ZDB-GENE-040718-162][more]
txn29.842e-1330.93thioredoxin 2 [Source:ZFIN;Acc:ZDB-GENE-040426-179... [more]
txnl11.244e-1033.75thioredoxin-like 1 [Source:ZFIN;Acc:ZDB-GENE-04042... [more]
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BLAST of Thioredoxin vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
btg5.35.498e-2443.90B-cell translocation gene 5, gene 3 [Source:Xenbas... [more]
ENSXETT00000029198.17.498e-2035.87MGC80314 protein [Source:NCBI gene;Acc:100170420][more]
btg5.32.527e-1938.30B-cell translocation gene 5, gene 3 [Source:Xenbas... [more]
tnfsf13b1.158e-1128.71TNF superfamily member 13b [Source:Xenbase;Acc:XB-... [more]
fabp23.409e-1135.37fatty acid binding protein 2 [Source:Xenbase;Acc:X... [more]
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BLAST of Thioredoxin vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Txn19.769e-1834.15thioredoxin 1 [Source:MGI Symbol;Acc:MGI:98874][more]
Txndc81.330e-1640.30thioredoxin domain containing 8 [Source:MGI Symbol... [more]
Txn23.792e-1329.35thioredoxin 2 [Source:MGI Symbol;Acc:MGI:1929468][more]
Txn28.355e-1329.35thioredoxin 2 [Source:MGI Symbol;Acc:MGI:1929468][more]
Txn28.355e-1329.35thioredoxin 2 [Source:MGI Symbol;Acc:MGI:1929468][more]
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BLAST of Thioredoxin vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q7KQL8|THIO_PLAF71.412e-2644.00Thioredoxin OS=Plasmodium falciparum (isolate 3D7)... [more]
sp|P42115|THIO_NEUCR4.498e-2537.40Thioredoxin OS=Neurospora crassa (strain ATCC 2469... [more]
sp|Q1RQI9|THIO_MALSM4.945e-2441.18Thioredoxin (Fragment) OS=Malassezia sympodialis O... [more]
sp|Q0DKF1|TRH42_ORYSJ2.613e-2242.00Thioredoxin H4-2 OS=Oryza sativa subsp. japonica O... [more]
sp|Q38879|TRXH2_ARATH5.703e-2239.33Thioredoxin H2 OS=Arabidopsis thaliana OX=3702 GN=... [more]
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BLAST of Thioredoxin vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A061BCE45.604e-2643.56Thioredoxin OS=Cyberlindnera fabianii OX=36022 GN=... [more]
A0A1J1H8P72.900e-2547.00Thioredoxin OS=Plasmodium relictum OX=85471 GN=TRX... [more]
A0A1Y2CJT73.003e-2540.78Thioredoxin-domain-containing protein OS=Neocallim... [more]
A0A367JRN75.045e-2539.42Thioredoxin OS=Rhizopus stolonifer OX=4846 GN=TRX2... [more]
A0A1J1GQR96.986e-2547.00Thioredoxin OS=Plasmodium gallinaceum OX=5849 GN=P... [more]
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BLAST of Thioredoxin vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
txn1.893e-1937.74thioredoxin-like [Source:NCBI gene;Acc:103039731][more]
zgc:564934.431e-1836.00thioredoxin-like [Source:NCBI gene;Acc:103040975][more]
txn24.505e-1329.41thioredoxin 2 [Source:NCBI gene;Acc:103028978][more]
txnl12.422e-1032.50thioredoxin like 1 [Source:NCBI gene;Acc:103021638... [more]
txnl12.526e-1032.50thioredoxin like 1 [Source:NCBI gene;Acc:103021638... [more]
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BLAST of Thioredoxin vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSPMAT00000007779.16.924e-1733.02pep scaffold:Pmarinus_7.0:GL477155:15795:22678:-1 ... [more]
ENSPMAT00000009652.14.924e-1636.56pep scaffold:Pmarinus_7.0:GL478563:4231:10899:-1 g... [more]
txn25.650e-1630.39thioredoxin 2 [Source:ZFIN;Acc:ZDB-GENE-040426-179... [more]
glrx32.287e-1023.71glutaredoxin 3 [Source:NCBI gene;Acc:449777][more]
txndc51.323e-829.58thioredoxin domain containing 5 [Source:ZFIN;Acc:Z... [more]
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BLAST of Thioredoxin vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 5
Match NameE-valueIdentityDescription
TRX18.319e-2233.67Cytoplasmic thioredoxin isoenzyme; part of thiored... [more]
TRX25.878e-2133.33Cytoplasmic thioredoxin isoenzyme; part of thiored... [more]
TRX36.486e-2136.36Mitochondrial thioredoxin; highly conserved oxidor... [more]
GRX41.334e-1231.13Glutathione-dependent oxidoreductase; hydroperoxid... [more]
GRX36.901e-1131.13Glutathione-dependent oxidoreductase; hydroperoxid... [more]
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BLAST of Thioredoxin vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO418526.440e-2245.12Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO461393.387e-2031.37Thioredoxin [Source:UniProtKB/TrEMBL;Acc:A7RQN2][more]
EDO333721.530e-1737.36Thioredoxin [Source:UniProtKB/TrEMBL;Acc:A7SSF5][more]
EDO454131.024e-1534.94Thioredoxin [Source:UniProtKB/TrEMBL;Acc:A7RT76][more]
EDO283626.626e-1440.79Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Thioredoxin vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSORLT00000009496.26.354e-2035.92thioredoxin [Source:NCBI gene;Acc:101173415][more]
txn24.511e-1127.00thioredoxin 2 [Source:NCBI gene;Acc:101164313][more]
txn24.714e-1127.00thioredoxin 2 [Source:NCBI gene;Acc:101164313][more]
glrx31.475e-1025.74glutaredoxin 3 [Source:NCBI gene;Acc:449777][more]
txnl13.816e-1030.30thioredoxin like 1 [Source:NCBI gene;Acc:101158293... [more]
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BLAST of Thioredoxin vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000023196.11.885e-91100.00SMESG000023196.1[more]
SMESG000023196.13.729e-85100.00SMESG000023196.1[more]
SMESG000023196.12.545e-7798.20SMESG000023196.1[more]
SMESG000023196.15.026e-7198.06SMESG000023196.1[more]
SMESG000039109.12.981e-1836.00SMESG000039109.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30017237 ID=SMED30017237|Name=Thioredoxin|organism=Schmidtea mediterranea sexual|type=transcript|length=516bp
CAAAATAAAAATTTATTCTTGTTTAGATTAATCAGATTCTGATTTAATAA
TTAAATAATTTTTGTCTAATTTGCATTAATCATTCGATTTGAGTCGTTCA
GAAAACCGTCTAAATGCCAGTTATCCACATAAGCTCCATGAATGATTTCG
TGCGCAGAATTGATCAAAATGGAAAAATCATTGCTGATTTCTCAGCTTCC
TGGTGTGGACCTTGCAATAATATTGCTCCCATATATGAAGATTTAAGTGA
AACTTATGACAAAATATCATTTTTAAAAATTGACGTTGATTCACAATCAG
ATATTGCTACTCTTTACAATATAACATCCTTGCCAACTTTTGTATTTTTC
AACCACGGAGCACAGATCCACATGATTATAGGGGCCGATGTTAACCAACT
GAAAAGTAATTTGGAGAAATTTAATGCAGAAATAGACAAAAAAATTTCTA
CTATGTCTGAATCAGTGAAATCTAAAAGATGCTGTCTACTTATCTAAATT
CCTGTTAAAATCAAAG
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protein sequence of SMED30017237-orf-1

>SMED30017237-orf-1 ID=SMED30017237-orf-1|Name=SMED30017237-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=128bp
MPVIHISSMNDFVRRIDQNGKIIADFSASWCGPCNNIAPIYEDLSETYDK
ISFLKIDVDSQSDIATLYNITSLPTFVFFNHGAQIHMIIGADVNQLKSNL
EKFNAEIDKKISTMSESVKSKRCCLLI*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000499cell
PLANA:0002089reproductive organ
Vocabulary: INTERPRO
TermDefinition
IPR036249Thioredoxin-like_sf
IPR012336Thioredoxin-like_fold
IPR013766Thioredoxin_domain
IPR017937Thioredoxin_CS
Vocabulary: biological process
TermDefinition
GO:0045454cell redox homeostasis
GO:0006662glycerol ether metabolic process
GO:0034599cellular response to oxidative stress
GO:0055114oxidation-reduction process
GO:0098869cellular oxidant detoxification
Vocabulary: molecular function
TermDefinition
GO:0004791thioredoxin-disulfide reductase activity
GO:0015035protein disulfide oxidoreductase activity
GO:0016671oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor
GO:0047134protein-disulfide reductase activity
Vocabulary: cellular component
TermDefinition
GO:0005829cytosol
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 93..113
NoneNo IPR availablePRINTSPR00421THIOREDOXINcoord: 22..30
score: 43.27
coord: 30..39
score: 62.33
coord: 69..80
score: 33.98
NoneNo IPR availablePANTHERPTHR46115:SF1THIOREDOXIN-LIKE PROTEIN 1coord: 1..112
NoneNo IPR availablePANTHERPTHR46115FAMILY NOT NAMEDcoord: 1..112
NoneNo IPR availableCDDcd02947TRX_familycoord: 11..101
e-value: 8.11905E-32
score: 106.103
IPR036249Thioredoxin-like superfamilyGENE3DG3DSA:3.40.30.10coord: 1..112
e-value: 8.3E-31
score: 108.1
IPR036249Thioredoxin-like superfamilySUPERFAMILYSSF52833Thioredoxin-likecoord: 2..105
IPR013766Thioredoxin domainPFAMPF00085Thioredoxincoord: 8..101
e-value: 8.2E-24
score: 83.6
IPR013766Thioredoxin domainPROSITEPS51352THIOREDOXIN_2coord: 1..112
score: 11.555
IPR017937Thioredoxin, conserved sitePROSITEPS00194THIOREDOXIN_1coord: 23..41