Amiloride-sensitive sodium channel subunit gamma

Overview
NameAmiloride-sensitive sodium channel subunit gamma
Smed IDSMED30017185
Length (bp)1675
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Amiloride-sensitive sodium channel subunit gamma (SMED30017185) t-SNE clustered cells

Violin plots show distribution of expression levels for Amiloride-sensitive sodium channel subunit gamma (SMED30017185) in cells (dots) of each of the 12 neoblast clusters.

 

back to top

 

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

back to top
Anatomical Expression

PAGE et. al., 2020



SMED30017185

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 3

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
prepharyngeal regionSMED30017185h1SMcG0000982 SmedASXL_004595SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016		whole organism asexual adult RNA-sequencing evidence
parapharyngeal regionSMED30017185h1SMcG0000982 SmedASXL_004595SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016		whole organism asexual adult RNA-sequencing evidence
parapharyngeal regionSMED30017185h1SMcG0000982 dd_Smed_v6_29341_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017		whole organism asexual adult RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. Ensembl Human
Match: SCNN1B (sodium channel epithelial 1 beta subunit [Source:HGNC Symbol;Acc:HGNC:10600])

HSP 1 Score: 56.6102 bits (135), Expect = 9.523e-8
Identity = 73/372 (19.62%), Postives = 129/372 (34.68%), Query Frame = 2 
Query:  467 QDFILKCSFGHVDCDFYIWKLHRHPSKFNCYSFT--PPENLLGTA--GKMNGMTLLLHYGKEN-LSFLRKLEKTFQFRGFYVAFHDSNSIPNFENHPLQVDVGKRTFIEIFTKKYQFIKRKQFNCVSNEESIHMINKINNYSTG----KCYNDLVQANFLEKCNCLS-IYHYPINERLGNFTEVLRSGCLSLGLPVQTLKDLISQYQSNSTLLNLLRKRVQCFRYFISSPAYINQHKHCLPLCNQTEFMNSYFNSDWPHDPYEAKLYIMKSLKRNLQLSLKYEYDEQMLRKWITFYEDLFSKPSNFSDYSETETTVKSRFALVHLYFRDSHVELMKQELVYPQITLWSEIGGAMGMWIGCSFFSIVYVAKVV 1552
            +  IL C FG   C++  +    +P   NCY F     E  L +A  G   G+ L+L  G+E+ + FL          G  +  H+  S P   +  +    G  T I +   K Q +      C  N   + + N  ++Y+T      C     Q + +  CNC   +Y  P  E+  N                   +D        S L   + +R  C                C   CN T++  +   +DWP +  E  ++ + S +R                                 D S   T  +     +++YF++ +   +++      + L S +GG  G W+G S   ++   +++
Sbjct:  243 EQMILACLFGAEPCNYRNFTSIFYPHYGNCYIFNWGMTEKALPSANPGTEFGLKLILDIGQEDYVPFLASTA------GVRLMLHEQRSYPFIRDEGIYAMSGTETSIGVLVDKLQRMGEPYSPCTVNGSEVPVQNFYSDYNTTYSIQACLRSCFQDHMIRNCNCGHYLYPLPRGEKYCNN------------------RDFPDWAHCYSDLQMSVAQRETCI-------------GMCKESCNDTQYKMTISMADWPSEASEDWIFHVLSQER---------------------------------DQSTNITLSRKGIVKLNIYFQEFNYRTIEESAANNIVWLLSNLGGQFGFWMGGSVLCLIEFGEII 544
[Close]
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. Ensembl Human
Match: SCNN1B (sodium channel epithelial 1 beta subunit [Source:HGNC Symbol;Acc:HGNC:10600])

HSP 1 Score: 56.225 bits (134), Expect = 1.228e-7
Identity = 73/372 (19.62%), Postives = 129/372 (34.68%), Query Frame = 2 
Query:  467 QDFILKCSFGHVDCDFYIWKLHRHPSKFNCYSFT--PPENLLGTA--GKMNGMTLLLHYGKEN-LSFLRKLEKTFQFRGFYVAFHDSNSIPNFENHPLQVDVGKRTFIEIFTKKYQFIKRKQFNCVSNEESIHMINKINNYSTG----KCYNDLVQANFLEKCNCLS-IYHYPINERLGNFTEVLRSGCLSLGLPVQTLKDLISQYQSNSTLLNLLRKRVQCFRYFISSPAYINQHKHCLPLCNQTEFMNSYFNSDWPHDPYEAKLYIMKSLKRNLQLSLKYEYDEQMLRKWITFYEDLFSKPSNFSDYSETETTVKSRFALVHLYFRDSHVELMKQELVYPQITLWSEIGGAMGMWIGCSFFSIVYVAKVV 1552
            +  IL C FG   C++  +    +P   NCY F     E  L +A  G   G+ L+L  G+E+ + FL          G  +  H+  S P   +  +    G  T I +   K Q +      C  N   + + N  ++Y+T      C     Q + +  CNC   +Y  P  E+  N                   +D        S L   + +R  C                C   CN T++  +   +DWP +  E  ++ + S +R                                 D S   T  +     +++YF++ +   +++      + L S +GG  G W+G S   ++   +++
Sbjct:  216 EQMILACLFGAEPCNYRNFTSIFYPHYGNCYIFNWGMTEKALPSANPGTEFGLKLILDIGQEDYVPFLASTA------GVRLMLHEQRSYPFIRDEGIYAMSGTETSIGVLVDKLQRMGEPYSPCTVNGSEVPVQNFYSDYNTTYSIQACLRSCFQDHMIRNCNCGHYLYPLPRGEKYCNN------------------RDFPDWAHCYSDLQMSVAQRETCI-------------GMCKESCNDTQYKMTISMADWPSEASEDWIFHVLSQER---------------------------------DQSTNITLSRKGIVKLNIYFQEFNYRTIEESAANNIVWLLSNLGGQFGFWMGGSVLCLIEFGEII 517
[Close]
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. Ensembl Human
Match: SCNN1B (sodium channel epithelial 1 beta subunit [Source:HGNC Symbol;Acc:HGNC:10600])

HSP 1 Score: 55.8398 bits (133), Expect = 1.541e-7
Identity = 73/372 (19.62%), Postives = 129/372 (34.68%), Query Frame = 2 
Query:  467 QDFILKCSFGHVDCDFYIWKLHRHPSKFNCYSFT--PPENLLGTA--GKMNGMTLLLHYGKEN-LSFLRKLEKTFQFRGFYVAFHDSNSIPNFENHPLQVDVGKRTFIEIFTKKYQFIKRKQFNCVSNEESIHMINKINNYSTG----KCYNDLVQANFLEKCNCLS-IYHYPINERLGNFTEVLRSGCLSLGLPVQTLKDLISQYQSNSTLLNLLRKRVQCFRYFISSPAYINQHKHCLPLCNQTEFMNSYFNSDWPHDPYEAKLYIMKSLKRNLQLSLKYEYDEQMLRKWITFYEDLFSKPSNFSDYSETETTVKSRFALVHLYFRDSHVELMKQELVYPQITLWSEIGGAMGMWIGCSFFSIVYVAKVV 1552
            +  IL C FG   C++  +    +P   NCY F     E  L +A  G   G+ L+L  G+E+ + FL          G  +  H+  S P   +  +    G  T I +   K Q +      C  N   + + N  ++Y+T      C     Q + +  CNC   +Y  P  E+  N                   +D        S L   + +R  C                C   CN T++  +   +DWP +  E  ++ + S +R                                 D S   T  +     +++YF++ +   +++      + L S +GG  G W+G S   ++   +++
Sbjct:  288 EQMILACLFGAEPCNYRNFTSIFYPHYGNCYIFNWGMTEKALPSANPGTEFGLKLILDIGQEDYVPFLASTA------GVRLMLHEQRSYPFIRDEGIYAMSGTETSIGVLVDKLQRMGEPYSPCTVNGSEVPVQNFYSDYNTTYSIQACLRSCFQDHMIRNCNCGHYLYPLPRGEKYCNN------------------RDFPDWAHCYSDLQMSVAQRETCI-------------GMCKESCNDTQYKMTISMADWPSEASEDWIFHVLSQER---------------------------------DQSTNITLSRKGIVKLNIYFQEFNYRTIEESAANNIVWLLSNLGGQFGFWMGGSVLCLIEFGEII 589
[Close]
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. Ensembl Celegans
Match: asic-2 (Degenerin-like protein asic-2 [Source:UniProtKB/Swiss-Prot;Acc:Q22851])

HSP 1 Score: 69.707 bits (169), Expect = 2.708e-12
Identity = 93/489 (19.02%), Postives = 176/489 (35.99%), Query Frame = 2 
Query:  110 IFWLIVFTIVLTGFIIHTYYLYQRYIEEPIANILDITSNRVNWPAVTICPTNRIDGDRLQQN------NSSLWESDFFKLKTF----WQEF-DRNLSVNIREEISENLSAEYMYLNSNESKAARFPFRQPQDFILKCSFGHVDCDFYIWKLHRHPSKFNCYSFTPPENL---LGTAGKMNGMTLLLHYGKENLSFLRKLEKTFQFRGFYVAFHDSNSIPNFENHPLQVDVGKRTFIEIFTKKYQFIKRKQFNCVSNEESIHMINKINNYSTGKCYNDLVQANFLEKCNCLSIYHYPINERLGNFTEVLRSGCLSLGLPVQTLKDLISQYQSNSTLLNLLRKRVQCFRYFISSPAYINQHKHCLPLCNQTEFMNSYFNSDWPHDPYEAKLYIMKSLKRNLQLSLKYEYDEQMLRKWITFYEDLFSKPSNFSDYSETETTVKSRFALVHLYFRDSHVELMKQELVYPQITLWSEIGGAMGMWIGCSFFSIV 1534
            IFW+ +F  VL  F    Y L  ++   P     +I   +  +P VT+C  N      ++ N      N+ +       + TF    W  + D + + ++    ++ L  E   ++      A + +    D I  CSF  + C    +     P    CYSF    +L   +   G   G+ L+L   +   +       T +  G  +  +   S P  +++ +   VG  + + +   +    K+    CV  E       K   Y+   C+N   Q + + KC C        N RL   +    + C  +   +  L+ L     S++  ++LL   V+C               +C P C+++ +  +   + +P   Y    Y+  S    +                        S  S FS  S+ +    +   ++ ++      EL  +   Y    + +++GG  G+W+G S  S+V
Sbjct:   35 IFWIAIFLFVLGMFAYELYILIAKFFSYPATVNTEILFEKQIFPVVTVCNMNPYKYSVVKSNSAFSSVNTLMTTYSDATVGTFSTDKWGLYADNDETYDLDSRAADALVLEANLISDTAKVPALYTY---ADLIQDCSFAGIPCSESDFTKFIDPVYGACYSFNEDASLNYSVSREGIQFGLKLMLTVTQTKTNGNTDSLPTTKLAGARIGVNSRGSSPGLDSNGIDAGVGYESAVSVSLTQNVRAKKPYGTCVDREPDSSDYYKDFIYTLETCFNGCKQRDTIAKCQCA-------NPRLALGS--TDTACQPIKADLDCLQTLKGNQTSSTPNIDLL---VEC---------------NCNPPCDESTYTPTVSLAQFPSTSY----YVATSSTAGVG--------------------SCSSTNSKFSSKSDCQKWYNNNGMIIQVFLETLSYELYTETAGYTVSNVINDLGGQAGLWLGLSVISVV 469
[Close]
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. Ensembl Celegans
Match: unc-105 (Degenerin-like protein unc-105 [Source:UniProtKB/Swiss-Prot;Acc:Q09274])

HSP 1 Score: 62.7734 bits (151), Expect = 4.614e-10
Identity = 78/367 (21.25%), Postives = 138/367 (37.60%), Query Frame = 2 
Query:  470 DFILKCSFGHVDCDF-YIWKLHRHPSKFNCYSFT---PPENLLGTAGKMNGMTLLLHYGKENLSFLRKLEKTFQFRGFYVAFHDSNSIPNFENHPLQVDVGKRTFIEIFTKKYQFIKRKQFNCV-SNEESIHMINKINNYSTGKCYNDLVQANFLEKCNCLSIYHYPINERLGNFTEVLRSGCLSLGLPVQTLKDLISQYQSNSTL-LNLLRKRVQCFRYFISSPAYINQHKHCLPLCNQTEFMNSYFNSDWPHDPYEAKLYIMKSLKRNLQLSLKYEYDEQMLRKWITFYEDLFSKPSNFSDYSETETTVKSRFALVHLYFRDSHVELMKQELVYPQITLWSEIGGAMGMWIGCSFFSIVYVAKVV 1552
            + +LKCSF   DC     + LH   +  NCY+F      E     AG   G+ +LL+    N+S   +   T +  GF +  HD + +P  +        G  +   +  K++  ++    +C    E++   +     YS   C+    Q   +E C C     YP+ E  GN T+           P Q +     +   N+TL L  L         +      I    +C   C +T +  +Y ++ WP         +M+ L  +     KY  +  M++    FYE+L                               + E M++   Y   ++ +++GG  G+WIG S  S++ +  ++
Sbjct:  415 ELVLKCSFNQKDCQMDRDFTLHYDNTFGNCYTFNYNRTAEVASHRAGANYGLRVLLY---ANVS---EYLPTTEAVGFRITVHDKHIVPFPDAFGYSAPTGFMSSFGVRMKQFIRLEPPYGHCRHGGEDAATFVYTGFQYSVEACHRSCAQKVIVEACGCADPM-YPVAEMFGNNTK-----------PCQAVNMDQRECLRNTTLWLGEL---------YSKGKEAIIPDCYCHQPCQETNYEVTYSSARWP----SGSAKVMECLPGDFLCLEKYRKNAAMVQ---IFYEEL-------------------------------NYETMQESPAYTLTSVLADLGGLTGLWIGASVVSLLEIVTLI 716
[Close]
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. Ensembl Celegans
Match: unc-105 (Degenerin-like protein unc-105 [Source:UniProtKB/Swiss-Prot;Acc:Q09274])

HSP 1 Score: 62.7734 bits (151), Expect = 4.614e-10
Identity = 78/367 (21.25%), Postives = 138/367 (37.60%), Query Frame = 2 
Query:  470 DFILKCSFGHVDCDF-YIWKLHRHPSKFNCYSFT---PPENLLGTAGKMNGMTLLLHYGKENLSFLRKLEKTFQFRGFYVAFHDSNSIPNFENHPLQVDVGKRTFIEIFTKKYQFIKRKQFNCV-SNEESIHMINKINNYSTGKCYNDLVQANFLEKCNCLSIYHYPINERLGNFTEVLRSGCLSLGLPVQTLKDLISQYQSNSTL-LNLLRKRVQCFRYFISSPAYINQHKHCLPLCNQTEFMNSYFNSDWPHDPYEAKLYIMKSLKRNLQLSLKYEYDEQMLRKWITFYEDLFSKPSNFSDYSETETTVKSRFALVHLYFRDSHVELMKQELVYPQITLWSEIGGAMGMWIGCSFFSIVYVAKVV 1552
            + +LKCSF   DC     + LH   +  NCY+F      E     AG   G+ +LL+    N+S   +   T +  GF +  HD + +P  +        G  +   +  K++  ++    +C    E++   +     YS   C+    Q   +E C C     YP+ E  GN T+           P Q +     +   N+TL L  L         +      I    +C   C +T +  +Y ++ WP         +M+ L  +     KY  +  M++    FYE+L                               + E M++   Y   ++ +++GG  G+WIG S  S++ +  ++
Sbjct:  415 ELVLKCSFNQKDCQMDRDFTLHYDNTFGNCYTFNYNRTAEVASHRAGANYGLRVLLY---ANVS---EYLPTTEAVGFRITVHDKHIVPFPDAFGYSAPTGFMSSFGVRMKQFIRLEPPYGHCRHGGEDAATFVYTGFQYSVEACHRSCAQKVIVEACGCADPM-YPVAEMFGNNTK-----------PCQAVNMDQRECLRNTTLWLGEL---------YSKGKEAIIPDCYCHQPCQETNYEVTYSSARWP----SGSAKVMECLPGDFLCLEKYRKNAAMVQ---IFYEEL-------------------------------NYETMQESPAYTLTSVLADLGGLTGLWIGASVVSLLEIVTLI 716
[Close]
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. Ensembl Celegans
Match: unc-105 (Degenerin-like protein unc-105 [Source:UniProtKB/Swiss-Prot;Acc:Q09274])

HSP 1 Score: 62.7734 bits (151), Expect = 4.692e-10
Identity = 78/367 (21.25%), Postives = 138/367 (37.60%), Query Frame = 2 
Query:  470 DFILKCSFGHVDCDF-YIWKLHRHPSKFNCYSFT---PPENLLGTAGKMNGMTLLLHYGKENLSFLRKLEKTFQFRGFYVAFHDSNSIPNFENHPLQVDVGKRTFIEIFTKKYQFIKRKQFNCV-SNEESIHMINKINNYSTGKCYNDLVQANFLEKCNCLSIYHYPINERLGNFTEVLRSGCLSLGLPVQTLKDLISQYQSNSTL-LNLLRKRVQCFRYFISSPAYINQHKHCLPLCNQTEFMNSYFNSDWPHDPYEAKLYIMKSLKRNLQLSLKYEYDEQMLRKWITFYEDLFSKPSNFSDYSETETTVKSRFALVHLYFRDSHVELMKQELVYPQITLWSEIGGAMGMWIGCSFFSIVYVAKVV 1552
            + +LKCSF   DC     + LH   +  NCY+F      E     AG   G+ +LL+    N+S   +   T +  GF +  HD + +P  +        G  +   +  K++  ++    +C    E++   +     YS   C+    Q   +E C C     YP+ E  GN T+           P Q +     +   N+TL L  L         +      I    +C   C +T +  +Y ++ WP         +M+ L  +     KY  +  M++    FYE+L                               + E M++   Y   ++ +++GG  G+WIG S  S++ +  ++
Sbjct:  357 ELVLKCSFNQKDCQMDRDFTLHYDNTFGNCYTFNYNRTAEVASHRAGANYGLRVLLY---ANVS---EYLPTTEAVGFRITVHDKHIVPFPDAFGYSAPTGFMSSFGVRMKQFIRLEPPYGHCRHGGEDAATFVYTGFQYSVEACHRSCAQKVIVEACGCADPM-YPVAEMFGNNTK-----------PCQAVNMDQRECLRNTTLWLGEL---------YSKGKEAIIPDCYCHQPCQETNYEVTYSSARWP----SGSAKVMECLPGDFLCLEKYRKNAAMVQ---IFYEEL-------------------------------NYETMQESPAYTLTSVLADLGGLTGLWIGASVVSLLEIVTLI 658
[Close]
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. Ensembl Celegans
Match: unc-105 (Degenerin-like protein unc-105 [Source:UniProtKB/Swiss-Prot;Acc:Q09274])

HSP 1 Score: 62.7734 bits (151), Expect = 4.692e-10
Identity = 78/367 (21.25%), Postives = 138/367 (37.60%), Query Frame = 2 
Query:  470 DFILKCSFGHVDCDF-YIWKLHRHPSKFNCYSFT---PPENLLGTAGKMNGMTLLLHYGKENLSFLRKLEKTFQFRGFYVAFHDSNSIPNFENHPLQVDVGKRTFIEIFTKKYQFIKRKQFNCV-SNEESIHMINKINNYSTGKCYNDLVQANFLEKCNCLSIYHYPINERLGNFTEVLRSGCLSLGLPVQTLKDLISQYQSNSTL-LNLLRKRVQCFRYFISSPAYINQHKHCLPLCNQTEFMNSYFNSDWPHDPYEAKLYIMKSLKRNLQLSLKYEYDEQMLRKWITFYEDLFSKPSNFSDYSETETTVKSRFALVHLYFRDSHVELMKQELVYPQITLWSEIGGAMGMWIGCSFFSIVYVAKVV 1552
            + +LKCSF   DC     + LH   +  NCY+F      E     AG   G+ +LL+    N+S   +   T +  GF +  HD + +P  +        G  +   +  K++  ++    +C    E++   +     YS   C+    Q   +E C C     YP+ E  GN T+           P Q +     +   N+TL L  L         +      I    +C   C +T +  +Y ++ WP         +M+ L  +     KY  +  M++    FYE+L                               + E M++   Y   ++ +++GG  G+WIG S  S++ +  ++
Sbjct:  357 ELVLKCSFNQKDCQMDRDFTLHYDNTFGNCYTFNYNRTAEVASHRAGANYGLRVLLY---ANVS---EYLPTTEAVGFRITVHDKHIVPFPDAFGYSAPTGFMSSFGVRMKQFIRLEPPYGHCRHGGEDAATFVYTGFQYSVEACHRSCAQKVIVEACGCADPM-YPVAEMFGNNTK-----------PCQAVNMDQRECLRNTTLWLGEL---------YSKGKEAIIPDCYCHQPCQETNYEVTYSSARWP----SGSAKVMECLPGDFLCLEKYRKNAAMVQ---IFYEEL-------------------------------NYETMQESPAYTLTSVLADLGGLTGLWIGASVVSLLEIVTLI 658
[Close]
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. Ensembl Zebrafish
Match: asic4b (acid-sensing (proton-gated) ion channel family member 4b [Source:NCBI gene;Acc:407667])

HSP 1 Score: 58.9214 bits (141), Expect = 1.014e-8
Identity = 64/290 (22.07%), Postives = 113/290 (38.97%), Query Frame = 2 
Query:  113 FWLIVFTIVLTGFIIHTYYLYQRYIEEP-IANILDITSNRVNWPAVTICPTNRIDGDRLQQNNSSLWESDFFKLKTFWQEFDRNLSVNIREEISENLSAEYMYLNSNESKAARFPFRQPQDFILKCSFGHVDC---DFYIWKLHRHPSKFNCYSF----TPPENLLGTAGKMNGMTLLLHYGK-ENLSFLRKLEKTFQFRGFYVAFHDSNSIPNFENHPLQVDVGKRTFIEIFTKKYQFIKRKQFNCVSNEESIHMINKINNYSTGKCYNDLVQANFLEKCNCLSIYHYP 955
             W +   + L  F+    +    Y+E P +A + + T   + +PA+T+C  NR          S+L ++D + L         NL+    +    +  +E  Y   N     +    Q +D +  C+F   +C   DF +     +     CY+F    T P+ +    G  NG+ ++L   + E L   R+  +T    G  V  H  N  P        V  G +TF+    ++  ++ +   NC ++ E +  I   + YS   C           +CNC  + H P
Sbjct:   72 LWGLALLVSLGLFLYQATWSAATYLERPHLAALREETRRELTFPAITLCNVNRF-------RFSALTDADIYHLA--------NLTGLPPKSRKGHRPSELQYPPPNMLDIFQRTGHQLEDMLKSCNFSGQNCSSEDFSVV----YTRYGKCYTFNGNKTSPKRVR-QGGTGNGLEMMLDIQQDEYLPIWRETNETTLEAGIRVQIHSQNEPPYIHQLGFGVSPGFQTFVSCQEQRLTYLPQPWGNCRASSEPV--IPGYDTYSVSACRLHCESTQVQRECNC-RMVHMP 338
[Close]
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. Ensembl Zebrafish
Match: asic4a (acid-sensing (proton-gated) ion channel family member 4a [Source:NCBI gene;Acc:407668])

HSP 1 Score: 54.6842 bits (130), Expect = 2.053e-7
Identity = 95/482 (19.71%), Postives = 167/482 (34.65%), Query Frame = 2 
Query:  113 FWLIVFTIVLTGFIIHTYYLYQRYIEEPIANIL-DITSNRVNWPAVTICPTNRIDGDRLQQNNSSLWESDFFKLKTFWQEFDRNLSVNIREEISENLSAEYMYLNSNESKAARFPFRQPQDFILKCSFGHVDC---DF-YIWKLHRHPSKFNCYSFTPPENLLGTAGKMNGMTLLLHYGKEN-LSFLRKLEKTFQFRGFYVAFHDSNSIPNFENHPLQVDVGKRTFIEIFTKKYQFIKRKQFNCVSNEESIHMINKINNYSTGKCYNDLVQANFLEKCNCLSIYHYPINERLGNFTEVLRSGCLSLGLPVQTLKDLISQYQSNSTLLNLLRKRVQCFRYFISSPAYINQHKHCLPLCNQTEFMNSYFNSDWPHDPYEAKLYIMKSLKRNLQLSLKYEYDEQMLRKWITFYEDLFSKPSNFSDYSETETTVKSRFALVHLYFRDSHVELMKQELVYPQITLWSEIGGAMGMWIGCSFFSIVYV 1540
             W + F + L  F+         Y+E P    L +  +  + +PAVTIC  NR          S+L ++D + L         NL+    +    +   +  Y   +          Q ++ +  C+F   +C   DF  ++  +     FN    T  +   G  G  NG+ ++L   +++ L   ++  +T    G  V  H  +  P        V  G +TF+    ++  ++ +   NC S  E   MI   + YS   C         L +C C  + H P +  +   +++    C+   L        + Q  S  T          CF               C   CN T +              E  +  + S      LS KY+  E  +R                             F ++ ++F   + E ++Q+  Y    L  +IGG MG++IG S  +I+ +
Sbjct:   68 LWALAFLVSLALFLYQAAKCAISYLEHPHVTALNEEATPEMVFPAVTICNINRF-------RFSALTDADIYHLA--------NLTGLPPKNKDGHKPTDLEYPAPDMQDIFNRTGHQLEEMLKSCNFSGQNCSAEDFTVVYTRYGKCYTFNGNKTTSRKTKQGGMG--NGLEIMLDIQQDDYLPIWKETNETSLEAGIRVQIHSQDEPPYIHQLGFGVSPGFQTFVSCQEQRLTYLPQPWGNCRSTSE--QMIPGYDTYSISACRLRCETLEVLRECKC-RMVHMPGDANICTPSDI---KCVDKAL-------ALLQKSSGDT----------CF---------------CETPCNLTRYGK------------ELSMVKIPSKGSARYLSRKYDKSEDYIR---------------------------DNFLVLDIFFEALNYETIEQKKAYDVAGLLGDIGGQMGLFIGASVLTILEI 455
[Close]
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. Ensembl Xenopus
Match: foxe3 (forkhead box E3 [Source:Xenbase;Acc:XB-GENE-480592])

HSP 1 Score: 57.7658 bits (138), Expect = 3.624e-8
Identity = 76/372 (20.43%), Postives = 132/372 (35.48%), Query Frame = 2 
Query:  467 QDFILKCSFGHVDCDFYIWKLHRHPSKFNCYSFTP--PENLLGT--AGKMNGMTLLLHYG-KENLSFLRKLEKTFQFRGFYVAFHDSNSIPNFENHPLQVDVGKRTFIEIFTKKYQFIKRKQFNCVSNEESIHM-INKINNYSTGKCYNDLVQANFLEKCNCLSIYHYPI--NERLGNFTEVLRSG-CLSLGLPVQTLKDLISQYQSNSTLLNLLRKRVQCFRYFISSPAYINQHKHCLPLCNQTEFMNSYFNSDWPHDPYEAKLYIMKSLKRNLQLSLKYEYDEQMLRKWITFYEDLFSKPSNFSDYSETETTVKSRFALVHLYFRDSHVELMKQELVYPQITLWSEIGGAMGMWIGCSFFSIVYVAKVVY 1555
            ++FI  C F    C    +K   HP   +C++ TP   EN L +  AGK  G++L +    K N+  L       Q  G  +  H+ N  P  E+    +  G  T I +   + + +  K   C S+  ++ + +    +Y+   C N   Q    E C C   Y YP+       N+ +    G C                YQ    +L+    R  CF               C   C +T +  S   + WP    +   +++  L+  + L                F  D+                       +++Y+ +   + +++    P   L S +GG    W G S  S+V +A++V+
Sbjct:  235 KNFIFSCDFIQKPCTLREYKFFHHPIYGSCFTVTPQGKENALYSPRAGKKYGLSLKMKVDQKHNMPLLS------QAAGARIMIHNPNQPPRVEHQGFDIRPGTETSIGVKQDEVRHLGGKYGPCASDGNNLGLKLLYSTSYTLQACLNSCFQYKMTETCGC-GYYFYPLPPGTEYCNYNKHPGWGHCF---------------YQLYEKMLD---HRHHCF-------------TQCPMQCTKTRYQLSAGTAQWPSPTSKVCAFLLLELECKVTL--------------FNFRSDILK---------------------INVYYEELSYQSVEETPAMPVTLLLSNMGGQWSWWFGSSVLSVVEIAELVF 533
[Close]
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. Ensembl Mouse
Match: Scnn1g (sodium channel, nonvoltage-gated 1 gamma [Source:MGI Symbol;Acc:MGI:104695])

HSP 1 Score: 51.9878 bits (123), Expect = 1.686e-6
Identity = 73/371 (19.68%), Postives = 133/371 (35.85%), Query Frame = 2 
Query:  467 QDFILKCSFGHVDCDFYIWKLHRHPSKFNCYSFTPPENLLGTAGKMNGMTLLLHYGKENLSFLRKLEKT---FQFRGFYVAFHDSNSIPNFENHPLQVDVGKRTFIEIFTKKYQFIKRKQFNCVSNEESIHMINKIN-NYSTGKCYNDLVQANFLEKCNCLSIYHYPINERLGNFTEVLRSGCLSLGLPVQTLKDLISQYQSNSTLLNLLRKRVQCFRYFISSPAYINQHKHCLPLCNQT----EFMNSYFNSDWPHDPYEAKLYIMKSLKRNLQLSLKYEYDEQMLRKWITFYEDLFSKPSNFSDYSETETTVKSRFALVHLYFRDSHVELMKQELVYPQITLWSEIGGAMGMWIGCSFFSIVYVAKVVY 1555
            ++ ++ C F  + CD   + L  HP   NCY+F   EN    +  M G      YG + + ++ + E         G  V  H  N  P  E+   +++    T I +   +   +      C  +   + + N  N  YS   C     Q   +EKC C   Y  P+     N+                        YQ +   +         + Y+    A++ +   C  +C Q+    E+  +   + WP +  E  L  + +  ++ Q++ K    +  L K + FY+DL  +       S  E+   S             +E+           L S  GG +G+W+ CS   ++ + +V +
Sbjct:  260 EELLVTCFFDGMSCDARNFTLFHHPMYGNCYTFNNRENATILSTSMGGS----EYGLQVILYINEDEYNPFLVSSTGAKVLVHQQNEYPFIEDVGTEIETAMSTSIGMHLTESFKLSEPYSQCTEDGSDVPVTNIYNAAYSLQICLYSCFQTKMVEKCGCAQ-YSQPL-PPAANY----------------------CNYQQHPNWM---------YCYYQLYQAFVREELGCQSVCKQSCSFKEWTLTTSLAQWPSEASEKWLLNVLTWDQSQQINKKLNKTD--LAKLLIFYKDLNQR-------SIMESPANS-------------IEM-----------LLSNFGGQLGLWMSCSVVCVIEIIEVFF 560
[Close]
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. UniProt/SwissProt
Match: sp|Q22851|ASIC2_CAEEL (Degenerin-like protein asic-2 OS=Caenorhabditis elegans OX=6239 GN=asic-2 PE=3 SV=1)

HSP 1 Score: 69.707 bits (169), Expect = 3.445e-11
Identity = 93/489 (19.02%), Postives = 176/489 (35.99%), Query Frame = 2 
Query:  110 IFWLIVFTIVLTGFIIHTYYLYQRYIEEPIANILDITSNRVNWPAVTICPTNRIDGDRLQQN------NSSLWESDFFKLKTF----WQEF-DRNLSVNIREEISENLSAEYMYLNSNESKAARFPFRQPQDFILKCSFGHVDCDFYIWKLHRHPSKFNCYSFTPPENL---LGTAGKMNGMTLLLHYGKENLSFLRKLEKTFQFRGFYVAFHDSNSIPNFENHPLQVDVGKRTFIEIFTKKYQFIKRKQFNCVSNEESIHMINKINNYSTGKCYNDLVQANFLEKCNCLSIYHYPINERLGNFTEVLRSGCLSLGLPVQTLKDLISQYQSNSTLLNLLRKRVQCFRYFISSPAYINQHKHCLPLCNQTEFMNSYFNSDWPHDPYEAKLYIMKSLKRNLQLSLKYEYDEQMLRKWITFYEDLFSKPSNFSDYSETETTVKSRFALVHLYFRDSHVELMKQELVYPQITLWSEIGGAMGMWIGCSFFSIV 1534
            IFW+ +F  VL  F    Y L  ++   P     +I   +  +P VT+C  N      ++ N      N+ +       + TF    W  + D + + ++    ++ L  E   ++      A + +    D I  CSF  + C    +     P    CYSF    +L   +   G   G+ L+L   +   +       T +  G  +  +   S P  +++ +   VG  + + +   +    K+    CV  E       K   Y+   C+N   Q + + KC C        N RL   +    + C  +   +  L+ L     S++  ++LL   V+C               +C P C+++ +  +   + +P   Y    Y+  S    +                        S  S FS  S+ +    +   ++ ++      EL  +   Y    + +++GG  G+W+G S  S+V
Sbjct:   35 IFWIAIFLFVLGMFAYELYILIAKFFSYPATVNTEILFEKQIFPVVTVCNMNPYKYSVVKSNSAFSSVNTLMTTYSDATVGTFSTDKWGLYADNDETYDLDSRAADALVLEANLISDTAKVPALYTY---ADLIQDCSFAGIPCSESDFTKFIDPVYGACYSFNEDASLNYSVSREGIQFGLKLMLTVTQTKTNGNTDSLPTTKLAGARIGVNSRGSSPGLDSNGIDAGVGYESAVSVSLTQNVRAKKPYGTCVDREPDSSDYYKDFIYTLETCFNGCKQRDTIAKCQCA-------NPRLALGS--TDTACQPIKADLDCLQTLKGNQTSSTPNIDLL---VEC---------------NCNPPCDESTYTPTVSLAQFPSTSY----YVATSSTAGVG--------------------SCSSTNSKFSSKSDCQKWYNNNGMIIQVFLETLSYELYTETAGYTVSNVINDLGGQAGLWLGLSVISVV 469
[Close]
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. UniProt/SwissProt
Match: sp|K7FQW8|SCNNB_PELSI (Amiloride-sensitive sodium channel subunit beta OS=Pelodiscus sinensis OX=13735 GN=SCNN1B PE=3 SV=1)

HSP 1 Score: 67.0106 bits (162), Expect = 2.219e-10
Identity = 80/372 (21.51%), Postives = 136/372 (36.56%), Query Frame = 2 
Query:  461 QPQDFILKCSFGHVDCDFYIWKLHRHPSKFNCYSFT---PPENLLGT-AGKMNGMTLLLHYGKENLSFLRKLEKTFQFRGFYVAFHDSNSIPNFENHPLQVDVGKRTFIEIFTKKYQFIKRKQFNCVSNEESIHMINKINNYSTG----KCYNDLVQANFLEKCNCLSIYHYPINERLGNFTEVLRSGCLSLGLPVQTLKDLISQYQSNSTLLNLLRKRVQCFRYFISSPAYINQHKHCLPLCNQTEFMNSYFNSDWPHDPYEAKLYIMKSLKRNLQLSLKYEYDEQMLRKWITFYEDLFSKPSNFSDYSETETTVKSRFALVHLYFRDSHVELMKQELVYPQITLWSEIGGAMGMWIGCSFFSIVYVAKVV 1552
            QP+D IL C +G   C +  +    HP   NCY F      E L  +  G   G+ L+L   +++  ++  L  T    G  +  H+  S P  ++  +    G  T I +   + + +     +C  N   + + N  N Y+T      C     QA   E C C   Y +P+ E +        S C S   P     D    Y S       LR  +   ++ I S         C   CN  ++  +   +DWP +  E   Y        +Q  L YE D+                       S   T  ++    +++YF++ +   + +      + L S +GG  G W+G S   ++   +++
Sbjct:  258 QPEDMILACLYGAEPCSYRNFTPIYHPDHGNCYIFNWGKDEEALFSSNPGAEFGLKLILDISQQD--YIPYLTST---AGARLMLHEQRSFPFLKDLGIYAMSGTETSIGVLVDELERMGFPYSDCTMNGSDVPVKNLYNEYNTTYSIQACLRSCFQAQMFETCGC-GHYLFPLPEGV--------SYCNSEDDP-----DWAYCYSS-------LRSSIGHRQFCIDS---------CKETCNDIQYKMTISMADWPSEASEEFQY--------MQHPLTYERDQ-----------------------SRNATLDRNGIIKLNIYFQEYNYRTISESAATTIVWLLSSLGGQFGFWMGGSVLCLIEFGEII 563
[Close]
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. UniProt/SwissProt
Match: sp|Q09274|UN105_CAEEL (Degenerin-like protein unc-105 OS=Caenorhabditis elegans OX=6239 GN=unc-105 PE=1 SV=3)

HSP 1 Score: 62.7734 bits (151), Expect = 5.870e-9
Identity = 78/367 (21.25%), Postives = 138/367 (37.60%), Query Frame = 2 
Query:  470 DFILKCSFGHVDCDF-YIWKLHRHPSKFNCYSFT---PPENLLGTAGKMNGMTLLLHYGKENLSFLRKLEKTFQFRGFYVAFHDSNSIPNFENHPLQVDVGKRTFIEIFTKKYQFIKRKQFNCV-SNEESIHMINKINNYSTGKCYNDLVQANFLEKCNCLSIYHYPINERLGNFTEVLRSGCLSLGLPVQTLKDLISQYQSNSTL-LNLLRKRVQCFRYFISSPAYINQHKHCLPLCNQTEFMNSYFNSDWPHDPYEAKLYIMKSLKRNLQLSLKYEYDEQMLRKWITFYEDLFSKPSNFSDYSETETTVKSRFALVHLYFRDSHVELMKQELVYPQITLWSEIGGAMGMWIGCSFFSIVYVAKVV 1552
            + +LKCSF   DC     + LH   +  NCY+F      E     AG   G+ +LL+    N+S   +   T +  GF +  HD + +P  +        G  +   +  K++  ++    +C    E++   +     YS   C+    Q   +E C C     YP+ E  GN T+           P Q +     +   N+TL L  L         +      I    +C   C +T +  +Y ++ WP         +M+ L  +     KY  +  M++    FYE+L                               + E M++   Y   ++ +++GG  G+WIG S  S++ +  ++
Sbjct:  415 ELVLKCSFNQKDCQMDRDFTLHYDNTFGNCYTFNYNRTAEVASHRAGANYGLRVLLY---ANVS---EYLPTTEAVGFRITVHDKHIVPFPDAFGYSAPTGFMSSFGVRMKQFIRLEPPYGHCRHGGEDAATFVYTGFQYSVEACHRSCAQKVIVEACGCADPM-YPVAEMFGNNTK-----------PCQAVNMDQRECLRNTTLWLGEL---------YSKGKEAIIPDCYCHQPCQETNYEVTYSSARWP----SGSAKVMECLPGDFLCLEKYRKNAAMVQ---IFYEEL-------------------------------NYETMQESPAYTLTSVLADLGGLTGLWIGASVVSLLEIVTLI 716
[Close]
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. UniProt/SwissProt
Match: sp|H1AFJ5|SCNNA_NEOFS (Amiloride-sensitive sodium channel subunit alpha OS=Neoceratodus forsteri OX=7892 GN=scnn1a PE=1 SV=1)

HSP 1 Score: 61.2326 bits (147), Expect = 1.867e-8
Identity = 80/375 (21.33%), Postives = 140/375 (37.33%), Query Frame = 2 
Query:  461 QPQDFILKCSFGHVDCDFYIWKLHRHPSKFNCYSFTPPENLLGTA----GKMNGMTLLLHYGKEN-LSFLRKLEKTFQFRGFYVAFHDSNSIPNFENHPLQVDVGKRTFIEIFTKKYQFIKRKQFNCVSNEESIHMINKIN-NYSTGKCYNDLVQANFLEKCNCLSIYHYPINERLGNFTEVLRSGCLSLGLPVQTLKDLISQYQSNSTLLNLLRKRVQCFRYFISSPAYINQH----KHCLPLCNQTEFMNSYFNSDWPHDPYEAKLYIMKSLKRNLQLSLKYEYDEQMLRKWITFYEDLFSKPSNFSDYSETETTVKSRFALVHLYFRDSHVELMKQELVYPQITLWSEIGGAMGMWIGCSFFSIVYVAKVVY 1555
            Q  +F+  C F  V C    +   RHP   NCY++   ++    A    G  NG++L+L   + + L FL  +       G  V  HD N  P  E+  L +  G  T I +  +    +     NC    + I ++N  N +Y+   C     QA  +++C C   Y YP           L SG               ++Y S S      R +   + Y+    A+        + C   C  T++  +   + WP    E+                           WIT    + S+ + ++  S  +   K     +++YF + + + M +   +  +TL S +G    +W G S  S+V + ++V+
Sbjct:  244 QISNFVYACEFNKVSCGVENYTRFRHPVYGNCYTYNDGQSATPWASFVPGVGNGLSLVLRTEQNDFLPFLSTVA------GARVLVHDQNQPPFMEDSGLDIRPGVETSIGMKKEIISRLGGVYGNCTDGSD-IDVVNLYNSDYNQQACVRSCFQATIVQQCGC-GYYFYP-----------LPSG---------------AEYCSYS------RNKSWGYCYYKLYKAFAADELGCFRRCRKPCQYTDYKMTAGYAQWPSSVSES---------------------------WIT---SILSQENQYNMTSGRKNIAK-----LNVYFYELNYQTMGESPSFTVVTLLSNMGSQWSLWFGSSVLSVVEMGELVF 543
[Close]
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. UniProt/SwissProt
Match: sp|Q25011|FANA_CORAP (FMRFamide-activated amiloride-sensitive sodium channel OS=Cornu aspersum OX=6535 PE=2 SV=1)

HSP 1 Score: 60.077 bits (144), Expect = 4.177e-8
Identity = 84/409 (20.54%), Postives = 159/409 (38.88%), Query Frame = 2 
Query:  467 QDFILKCSFGHVDCDFYIWKLHRHPSKFNCYSFTPPENL-LGTAGKMNGMTLLLHYGKENLSFLRKLEKTFQF-------RGFYVAFHDSNSIPNFENHPLQVDVGKRTFIEIFTKKYQFIKRKQFNCVSNEESIHMINKINNYSTGKCYNDLVQANFLEKCNCLSIYHYPINERLGNFTEVLRSGCLSLGLPV-----QTLKDLISQYQS-NSTLLNLLRKRVQCFRYFISSPAYINQHKH---------------CLPLCNQTEFMNSYFNSDWPHDPYEAKLYIMKSLKRNLQ------LSLKYEYDEQM-------LRKWITFYEDLFSKPSNFSD---YSETETTVKSRFALVHLYFRDSHVELMKQELVYPQITLWSEIGGAMGMWIGCSFFSIVYVAKVVYK 1558
            +D ++ C F    C    +      + FNC++F   + L +   G  NG++L+    K++   L      + F        G  V  H   S+P+  +H + +  G  + + +    +  +     NC ++     M+N I  Y          +  F     CL +      +RL     + R GC S  LP       T   +I  +Q  N    N    + +  R FI +P    + +                C   C++T ++ S   S WP + Y+    + +  K+  Q      +   YEY E++       L +  +  +D+ SK  + S+     E    ++     +++Y  D  V   +Q   Y    L+++IGG +G+W+G S  +I+ + ++V +
Sbjct:  179 EDMLMHCRFNRELCHVSNFSTFFDGNYFNCFTFNSGQRLQMHATGPENGLSLIFSVEKDDP--LPGTYGVYNFDNNILHSAGVRVVVHAPGSMPSPVDHGIDIPPGYSSSVGLKAILHTRLPYPYGNCTND-----MLNGIKQY----------KYTFFA---CLQL----CKQRL----IIQRCGCKSSALPEVPSYNATFCGVIKDWQEINRNHSNEDHNQSEEDRAFIPTPYLACEEREQKNLNNDRTYELSCGCFQPCSETSYLKSVSLSYWPLEFYQLSA-VERFFKQERQAGQNHFMKTAYEYLEKLAHPSQKHLARNDSHMDDILSKSYSLSEKEMAKEASDLIRQNMLRLNIYLEDLSVVEYRQLPAYGLADLFADIGGTLGLWMGISVLTIMELIELVIR 558
[Close]
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. TrEMBL
Match: A0A1I8IIE8 (RRM domain-containing protein OS=Macrostomum lignano OX=282301 PE=3 SV=1)

HSP 1 Score: 115.161 bits (287), Expect = 5.477e-23
Identity = 112/510 (21.96%), Postives = 206/510 (40.39%), Query Frame = 2 
Query:  116 WLIVFTIVLTGFIIHTYYLYQRYIEEPIANILDITSNRVNWPAVTICPTNRIDGDRLQQN------NSSLWESDFFKLKTFW---QEFDRNLSVNIREEISENLSAEYMYLNSNESKAARFPFRQPQDFILKCSFGHVDCDFYIWKLHRHPSKFNCYSFTPPENLLGTAGKMNGMTLLLHYGKENLSFLRKLEKTFQFRGFYVAFHDSNSIPN-FENHPLQVDVGKRTFIEIFTKKYQFIKRKQFNCVSNEESIHMINKIN-----NYSTGKCYNDLVQANFLEKCNCLSIYHYPINERLGNFTEVLRSGCLSLGLPVQTLKDLISQYQSNSTLLNLLRKRVQCFRYFISSPAYINQHKH--------CLPLCNQTEFMNSYFNSDWPHDPYEAKLYIMKSLKRNLQLSLKYEYDEQMLRKWITFYEDLFSKPSNFSDYSETETTVKSRFALVHLYFRDSHVELMKQELVYPQITLWSEIGGAMGMWIGCSFFS----IVYVAKVVYKHF 1564
            WL +      GF  H + L+ RY+E P+     +   +  +P VTIC T+     R QQN      N S  E     ++TFW   +  D N+S+N   ++  ++ +    LN           +Q Q+ IL C F    C +  + L+  P+ F+CY+F P E  L   G+ +G   ++ Y  +  +F+   E      GF    H+  + P   E   +Q D    T++++   +   +K    +  +N +++  +++ N      Y+   C  +  Q      C+C+S    P+   L +   V    C S+    ++L + I Q  +      + R +    R           HK         C   C    +   +  + WP    E    + ++++R + L+ +   D   L +      D   +P+            +  FA + +Y   +   +M++   YP   L S+IGG +G+W+G S  S    +   A++++ HF
Sbjct:   55 WLFIILAAGAGFTAHLFALFSRYLERPVNTETSVYGTKFVFPDVTICATSHFSRLRYQQNPPVPSLNISTHEL-LHHIRTFWDPGENADTNISIN--ADVMHSIKSYLRELNIT---------KQRQEMILHCDFAGDSCSYRNFSLYVDPNYFSCYTFAPTERHLIVGGERDGGLNVIMYVGDVKNFITGEESLSYSEGFRAVIHEPGTRPELLEGFYVQRDTS--TYVQLGYTEEVVLKNCSLD--ANFQTVKFVDRYNRITEYRYTIRDCLVNTYQTYLRTNCSCVS-EALPLPANLNSNLSV--PFCHSISR--ESLMESIDQQAATEAEAAIERNQAAEHRRACHDSVVSEIHKKTSGLAPDVCPLRCKNVRYEMRFTQNRWPSACNETSQALAEAVERTIALAAEQGDDLTTLVEIQRRMSDEHREPA-----------FRESFAKLTIYTHSTMGSVMRESWAYPDRNLASDIGGILGLWLGVSIISTFEFLELFARLLFWHF 532
[Close]
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. TrEMBL
Match: A0A267EP27 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig015385g2 PE=3 SV=1)

HSP 1 Score: 111.694 bits (278), Expect = 5.076e-22
Identity = 136/596 (22.82%), Postives = 222/596 (37.25%), Query Frame = 2 
Query:   20 CHKFSFMNLKTIQNSRIFSLMKELRYQPIVIFWLIVFTIVLTGFIIHTYYLYQRYIEEPIANILDITSNRVNWPAVTIC---PTN----RIDGDRLQQNNSSLWESDFFKLKTFWQEFDRNLSVNIREEISENLSAEYMYLNSNESKAARFPFRQPQDFILKCSFGHVDCDFYIWKLHRHPSKFNCYSFTPPENLLGTAGKMNGMTLLLHYGK---------------------------ENLSFLRKLEKTFQFRGFYVAFHDSNSIPNFENHPLQVDVGKRTFIEIFTKKYQFIKRKQFNCVSNEESIHMINKIN----------NYSTGKCYNDLVQANFLEKCNCLSIYHYPINERLGNFTEVLR-----------SGCLSLGLPVQTL---------------KDLISQYQSNSTLLNLLRKRVQCFRYFI---SSPAY------INQHKHCLPLCNQTEFMNSYFNSDWPH--DPYE-AKLYIMKSL---KRNLQLSLKYEYDEQMLRKWITFYEDLFSKPSNFSDYSETETTVKSRFALVHLYFRDSHVELMKQELVYPQITLWSEIGGAMGMWIGCSFFSIVYVAKVV 1552
            C    F    TI      S M + +     IFWL VF + L   I+H  +   +++E P    LD   +   +P VTIC   PT         ++     +     D      + Q +D    +  +EEI  +         S  +K   F      + ++KCSF   DC    + L ++P   NCY+F PPE  L T    +G+ LLL+ G                             N  F R L   ++  G  + FH+ ++ P        V  G+ + IE+   + + + +    CV  E  +  +  ++          N   G C  +  Q +  ++C C S +  P+      F  + R           S  L LGL V  +               K  I    +NS L+    +RV C    +   S P Y       +  +  L  C + E+ + +  + WP   D  E  +  I+ +L   K NL    K + + + L        DLF   SN    ++ E  VK  F  + L+  +  V + ++E  Y       E+GG +G+W+G SF  ++ V + V
Sbjct:   21 CQMSGFCQRTTIHG---LSHMYQSKTSKRKIFWLTVFVLGLVATIVHLTFHAMQFLESPTIITLDHEGSEFEFPDVTICSQTPTTSRFYERGTEKFPNIQNGFTAMDLLLYPVYNQTYDSVHLLPYKEEILLHKRLIQHQYASMPTKHKGFAL---DELVIKCSFHKSDCRLQ-FTLLQNPYYLNCYTFQPPERNLKTTRPEDGLLLLLYIGNAQKNNIFPGKNATITSRSRPTSQKRETSNDWFARILLPEYEPAGVKIVFHEKDAFPALRAAGSIVGAGQFSEIELGMIQERKLNKGSSPCVDTEPKVWFLTSLDESGWPVFREFNAEPGDCIYEFQQRDLYKECGCTS-HRVPLQRDHKMFNSIDRGDQVGWCYNSTSLLLDLGLDVNQIVKSVKGDPAKLVNISKTAIQSSHANSRLVERYLRRVNCHDSLLDRFSDPHYNSIQQCTDGGEKALYACQKNEYKSVHSTASWPRYSDIQEIIEEDILPALLIPKNNLSDGNKTKVEYRPL------AHDLFDFDSNGQWIAQVE-LVKENFVKLQLHPVEVLVNVHREEPAYSIWEALGELGGIIGLWLGMSFLGVIEVCEFV 601
[Close]
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. TrEMBL
Match: A0A267GSY3 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig015385g1 PE=3 SV=1)

HSP 1 Score: 110.153 bits (274), Expect = 1.548e-21
Identity = 137/595 (23.03%), Postives = 222/595 (37.31%), Query Frame = 2 
Query:   20 CHKFSFMNLKTIQNSRIFSLMKELRYQPIVIFWLIVFTIVLTGFIIHTYYLYQRYIEEPIANILDITSNRVNWPAVTIC---PTN----RIDGDRLQQNNSSLWESDFFKLKTFWQEFDRNLSVNIREEISENLSAEYMYLNSNESKAARFPFRQPQDFILKCSFGHVDCDFYIWKLHRHPSKFNCYSFTPPENLLGTAGKMNGMTLLLHYGKE---------------------------NLSFLRKLEKTFQFRGFYVAFHDSNSIPNFENHPLQVDVGKRTFIEIFTKKYQFIKRKQFNCVSNEESIHMINKIN----------NYSTGKCYNDLVQANFLEKCNCLSIYHYPINERLGNFTEVLR-----------SGCLSLGLPVQTL---------------KDLISQYQSNSTLLNLLRKRVQCFRYFI---SSPAYINQHKHC-------LPLCNQTEFMNSYFNSDWPH--DPYE-AKLYIMKSL---KRNLQLSLKYEYDEQMLRKWITFYEDLFSKPSNFSDYSETETTVKSRFALVHLYFRDSHVELMKQELVYPQITLWSEIGGAMGMWIGCSFFSIVYVAK 1546
            C    F    TI      S M + +     IFWL VF + L   I+H  +   +++E P    LD   +   +P VTIC   PT         ++     +     D      + Q +D    +  +EEI  +         S  +K   F      + ++KCSF   DC    + L ++P   NCY+F PPE  L T    +G+ LLL+ G                             N  F R L   ++  G  + FH+ ++ P        V  G+ + IE+   + + + +    CV  E  +  +  ++          N   G C  +  Q +  ++C C S +  P+      F  + R           S  L LGL V  +               K  I    +NS L+    +RV C    +   S P Y N  + C       L  C + E+ + +  + WP   D  E  +  I+ +L   K NL    K + + + L        DLF   SN    ++ E  VK  F  + L+  +  V + ++E  Y       E+GG +G+W+G SF  ++ V +
Sbjct:   22 CQVSGFCQRTTIHG---LSHMYQSKTSKRKIFWLTVFVLGLVATIVHLTFHAMQFLESPTIITLDHEGSEFEFPDVTICSQTPTTSRFYERGTEKFPNIQNGFTAMDLLLYPVYNQTYDSVHLLPYKEEILLHKRLIQHQYASMPTKHKGFAL---DELVIKCSFHKSDCRLQ-FTLLQNPYYLNCYTFQPPERNLKTTRPEDGLLLLLYIGNAQKNNIFPGKNATITSRSRPTSQKRETGNDWFARILLPEYEPAGVKIVFHEKDAFPALRAAGSIVGAGQFSEIELGMIQERKLNKGSSPCVDTEPKVWFLTSLDESGWPVFREFNAEPGDCIYEFQQRDLYKECGCTS-HRVPLQRDHKMFNSIDRGDQVGWCYNSTSLLLDLGLDVNQIVKSVKGDPAKLVNISKTAIQSSHANSRLVERYLRRVNCHDSLLDRFSDPHY-NSIQQCTDGGEKALYACQKNEYKSVHSTASWPRYSDIQEIIEEDILPALLIPKNNLSDGNKTKVEYRPLA------HDLFDFDSNGQWTAQVE-LVKENFVKLQLHPVEVLVNVHREEPAYSIWEALGELGGIIGLWLGMSFLGVIEVCE 600
[Close]
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. TrEMBL
Match: A0A267G3Q5 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig003120g3 PE=3 SV=1)

HSP 1 Score: 102.834 bits (255), Expect = 2.796e-19
Identity = 109/495 (22.02%), Postives = 206/495 (41.62%), Query Frame = 2 
Query:  110 IFWLIVFTIVLTGFIIHTYYLYQRYIEEPIANILDITSNRVNWPAVTICPTNRIDGDRLQQN------NSSLWE--SDFFKLKTFWQEFDRNLSVNIREEISENLSAEYMYLNSNESKAARFPF-RQPQDFILKCSFGHVDCDFYIWKLHRHPSKFNCYSFTPPENLLGTAGKMNGMTLLLHYGKENLSFLRKLEKTFQFRGFYVAFHDSNSIPNFENHPLQVDVGKRTFIEI-FTKKYQFIKRKQFNCVSNEESIHMINKINN--YSTGKCYNDLVQANFL-EKCNCLSIYHYPINERLGNFTEVLRSGC---------LSLGLPVQTLKDLISQYQSNSTLLNLLRKRVQCFRYFISSPAYINQHKHCLPLCNQTEFMNSYFNSDWPHDPYEAKLYIMKSLKRNLQLSLKYEYDEQMLRKWITFYEDLFSKPSNFSDYSETETTVKSRFALVHLYFRDSHVELMKQELVYPQITLWSEIGGAMGMWIGCSFFS 1528
            I WL++     +GF  H   L+ R+ E P+   + + S    +P ++IC T+     R ++N      N  + E  SD   +++FW   + + S     EI+ +L      LNS +S        +Q Q+ IL C F    C +  +  +  P+ F+C++F+P E  L   G+ +G   ++ Y  + ++F+ + +     +GF    H+  + P        V     T++++ +T++    K  +   +   E +    K+    YS   C  +L Q NFL E C C+S    P+  +  N T    + C          S G        +  + + +   +N + K+V        S     +  +C   CN T +      + WP+D  E +  + ++ +R +  +       ++L + +   E L + P               RFA + +Y   +   ++++   Y    L S+IGG +G+W+G S  S
Sbjct:   66 IVWLLIIITAFSGFSAHLISLFSRFNEGPVNTEISVYSTNFVFPDISICATSHFSLRRYERNPKIRSLNKPIKELVSD---IRSFWDPNNESDS-----EINGDL------LNSLKSYLHEVNITKQSQEMILHCDFAGTICSYINFTEYIDPNYFSCFTFSPRERHLLVGGERDGGLSVIMYVGDMMNFISEEDSLRYSKGFRAVIHEKGTRPEML-EGFYVQEHACTYVQLGYTEEVVLRKCAEEESLQPLEFVDRYGKVTQYRYSVRDCQVNLYQ-NFLNESCRCVSEI-LPLPAKFRNITRHNITFCHHINEERLKQSRGAKSNDSSSVREKQECHDNAINEIHKQV--------SAKKTKKDSYCPLKCNNTRYEMRVMQNKWPNDANETRQALWEATQRTMHEARSRGDSTEVLEEIM---EHLKNDPYAL-----------QRFAKLTVYSHSTMGNIVRENWAYLARNLASDIGGILGLWLGVSIIS 521
[Close]
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. TrEMBL
Match: A0A267GVL0 (Uncharacterized protein (Fragment) OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig005363g1 PE=3 SV=1)

HSP 1 Score: 101.679 bits (252), Expect = 8.494e-19
Identity = 118/531 (22.22%), Postives = 205/531 (38.61%), Query Frame = 2 
Query:  110 IFWLIVFTIVLTGFIIHTYYLYQRYIEEPIANILDITSNRVNWPAVTICPTNRID--------------GDRLQQNNSSLWE-SDFFKLKTFWQEFDRNLSVNIREEISENLSAEYMYLNSNESKAARFPFRQPQDFILKCSFGHVDCDFYIWKLHRHPSKFNCYSFTPPENLLGTAGKMNGMTLLLHYGKENLSFLRKLEKTFQFRGFYVAFHDSNSIPNFENHPLQVDVGKRTFIEIFTKKYQFIKRKQFNCVSNEESIHMINKINNY-------------STGKCYNDLVQANFLEKCNCLSIYHYP----------------INERLGNFTEVLRSGCLSLGLPVQTLKD-------LISQYQSNSTLLNLLRKRVQCFRYFISSPAYINQHKHCLP-LC--NQTEFMNSYFNSDWPHDPYEAKLYIMKSLKRNLQLSLKYEYDEQMLRKWITFYEDLFSKPSNFSDYSETETTVKSRFALVHLYFRDSHVELMKQELVYPQITLWSEIGGAMGMWIGCSFFSIVYV 1540
            + W +V   V  GFI+H   L Q+Y   P++  L+  ++   +P VTIC TN +                 R +     +++ S FF L     + D N SV +    S       + LN    ++ + P   P + +L C F  + C +  + +++    F C +F P  N + +AG  NG+ LL++    + SF    E+     G  V  H     PN     +   +  +T   I T   + + R  + C+   ES+     I +Y             ST  C   ++Q  +L+ C CL+  H P                INE +  F ++      S      T+++       L+    +N  + N    R+ C++  +          H  P LC     E M  Y+   WP+    +   +       L  +     D + L+  ++ Y                E+ VK    ++ LY RD  V++  +   YP    +S++GG +G+WIG S  ++V +
Sbjct:   74 VLWALVVVGVCVGFILHLSMLVQQYTSYPVSTELEARTDFFEFPDVTICSTNYLSVTYGYDPVPSPVAVPGRARGLVDMIYDVSRFFHL---LNQTDMNASVPVNPYSSYRHGK--LALNKIAYRSKQLP--DPYEIVLLCRFNSIPCSYLNFTIYKDDELFKCMTFAPLNNTVVSAGPGNGLYLLMY--TYSSSFFTDEEEIDDIPGMKVVLHPRGVKPNMNGPHVMSPLKYKTEAVIDTSIQEKVDRSSYRCL---ESLPNATYITDYSQLTGPENETFRGSTEDCRVRIMQQEYLDTCGCLAT-HLPKPADLYYMAQPGVCHDINEHV-LFRDIFYRRPTS-SYTYYTIRNDSWYKYPLMDYVATNYDMYNGTIARLDCYQRVLDRQNREGVDTHGCPVLCRVKSHEVMPRYYQ--WPNSVKYSGKAVSNLATEALNEAKARGLDVRGLKDLVSNY----------------ESRVKYYAGVLDLYPRDLIVQMSIESWAYPLRNFFSDLGGILGLWIGASIVTLVEI 571
[Close]
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. Ensembl Cavefish
Match: asic4b (acid-sensing ion channel 4 [Source:NCBI gene;Acc:103044180])

HSP 1 Score: 49.2914 bits (116), Expect = 8.158e-6
Identity = 61/276 (22.10%), Postives = 106/276 (38.41%), Query Frame = 2 
Query:  161 TYYLYQR------YIEEP-IANILDITSNRVNWPAVTICPTNRIDGDRLQQNNSSLWESDFFKLKTFWQEFDRNLSVNIREEISENLSAEYMYLNSNESKAARFPFRQPQDFILKCSFGHVDCDFYIWKLHRHPSKFNCYSFT---PPENLLGTAGKMNGMTLLLHYGK-ENLSFLRKLEKTFQFRGFYVAFHDSNSIPNFENHPLQVDVGKRTFIEIFTKKYQFIKRKQFNCVSNEESIHMINKINNYSTGKCYNDLVQANFLEKCNCLSIYHYP 955
            T +LYQ       Y+E P +A + + +   + +PAVT+C  NR          S+L ++D + L         NL+    +    +   E  Y   +     +    Q +D +  C+F   +C  + + +  +     CY+F             G  NG+ L+L   + E L   R+  +T    G  V  H  +  P        V  G +TF+    ++  ++ +   NC ++ E +  I   + YS   C           +CNC  I H P
Sbjct:   85 TVFLYQASQSTAAYLEHPHLAALGEESRRELTFPAVTLCNVNRF-------RFSALTDADIYHLA--------NLTGLPPKSRGGHRPGELQYPPPDMLDIFQRTGHQLEDMLKSCNFSGQNCSVHDFSV-VYTRYGKCYTFNGNRTSAKRTRQGGMGNGLELMLDIQQDEYLPIWRETNETTLEAGIRVQIHSQDEPPYIHQLGFGVSPGFQTFVSCQEQRLSYLPQPWGNCRASTEPV--IPGYDTYSVSACRLHCESIQVQRECNCRMI-HMP 341
[Close]
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. Ensembl Nematostella
Match: EDO42137 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S2F2])

HSP 1 Score: 72.0182 bits (175), Expect = 2.231e-13
Identity = 110/510 (21.57%), Postives = 192/510 (37.65%), Query Frame = 2 
Query:  110 IFWLIVFTIVLTGFIIHTYYLYQRYIEEPIANILDIT-SNRVNWPAVTICPTNRIDGDRLQQNNSSLWE---SDFFKLKTFWQEFDRNLSVNIRE---EISENLSAEYMYLNSNESKAARFPFRQPQDFILKCSFGHVDC----DFYI---WKLHRHPSKFNCYSFTPPENLLG---------TAGKMNGMTLLLHYGKENLSFLRKLEKTFQFRGFYVAFHDSNSIPNFENHPLQVDVGKRTFIEIFTKKYQFIKRKQFNCVSNEESIHMINKI------NNYSTGKCYNDLVQANFLEKCNCLSIYHYPINERLGNFTEVLRSGCLSLGLPVQTLKDLISQYQSNSTLLNLLRKRVQCFRYFISSPAYINQHKHCLPLCNQTEFMNSYFNSDWPHDPYEAKLYIMKSLKRNLQLSLKYEYDEQMLRKWITFYEDLFSKPSNFSDYSETETTVKSRFALVHLYFRDSHVELMKQELVYPQITLWSEIGGAMGMWIGCSFFSIVYVAKVV 1552
            ++W++        F+     L  +Y  +PI     +  + ++++P VTIC  N +   RL     + ++   ++  K         RN  V+ ++   E ++     +     ++ +       Q +D +L C+F  V+C    D  I   W    + +  NCY F   +   G           G+ NG+TL L     NL     LE   +  G  V   D   +P      +++  G+ T I++   K Q  +   F   S E S  M +K         YS   C    + A  +E+C                       GC +   P    +++    + NST+++ L K    F          +  + C P C++  F  +  ++ WP   +E                 KY Y    LR  +     + S  S +   SE         A VH+Y+ +    L+++ L Y  ++L S+IGG MGMWIG S  +   + ++V
Sbjct:   40 LYWVMFCLAAYCVFVWQLVGLVNQYNSKPIKTRTQLKHAQKLDFPVVTICNMNVLRASRLPPKLRTKFDQIINNTNKTSPRNSSNSRNAFVDPQDLSFEETKKFEILHAVTAHDDYRELVSAAHQLEDILLSCNFNGVNCRNSKDPTIPTYWTQTWNDNFGNCYMFNSVKTHNGEKVDLYSSSVPGESNGLTLQL-----NLEQNEYLEGITEVAGMKVTISDQGVLPFPGQQGIRIMPGQSTGIQM--TKLQTRRIDPFKNRSCESSNEMSDKNLFFGYNMTYSIMACKYSCLNARKIERC-----------------------GCTNYNTPEMQKRNIPLCNRLNSTIIDCLNKAYDTFEDG-------SCDRECPPSCSEVSFDLTVSSARWPARSFEVT---------------KYAY---FLR--VRVLNKIASSSSKYFVNSEN-------IAQVHVYYGELDYLLVQETLAYTFMSLLSDIGGQMGMWIGISALTCAELIELV 485
[Close]
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. Ensembl Nematostella
Match: EDO30894 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SZH6])

HSP 1 Score: 52.373 bits (124), Expect = 3.114e-7
Identity = 72/355 (20.28%), Postives = 128/355 (36.06%), Query Frame = 2 
Query:  116 WLIVFTIVLTGFIIHTYYLYQRYIEEPIANILDITSNR-VNWPAVTICPTNRIDGDRLQQNNSSLWESDFFKLKTFWQEFDRNLSVNIREEISENLSAEYMYLNSNESKAARFPFRQPQDFILK------CSFGHVDCDFYIWKLHRHPSKFNCYSFTPPENL---LGTAGKMNGMTLLLHY-GKENLSFLRKLEKTFQFRGFYVAFHDSNSIPNFENHPLQVDVGKRTFIEIFTKKYQFIKRKQFNCVSNEESIHMINKINNYSTGKCYNDLVQANFLEKCNCLSIYHYPINERLGNFTEVLRSGCLSLGLPVQTLKDLISQYQSNSTLLNLLRKRVQCFRYFISSPAYINQHK 1147
            WL V      GFI  ++     +   P++ ++    ++ +N+PAVTIC  N I   R  QN  +L+                    N+  + S N+    ++L       +   +    D IL       C +   +C    +    H    +C++F         + + G ++G+ L L+   K+++S L  L+      GF V  HD    P  E     +  G  TF  +  K        +  C  N    +    + NY+   C    +    ++KC C  I+           +E + SG L+  L       L+  Y          R+  +CF+     P Y  +++
Sbjct:    1 WLFVVLAGFAGFIYQSFLSITSFYSWPVSTVMMTEWHKEMNFPAVTICNFNPISKSRYAQNYGNLF--------------------NLSTQDSNNIINGIIFLIGPMLGKSLRSYAHSIDGILSLKWLEPCKYSGKECGKNSFSTFEHLRYGSCHTFNSDGQFGLKVDSIGPISGLQLRLNVEEKDHVSNLYGLQA-----GFKVLVHDPREHPMIEETGFALQPGTHTFCSVRMKYVNLKAPYRTECGENITDFNRYFNV-NYTMAICSKQCLHDYGIKKCGCQPIFEIT--------SEFMDSGSLTHCL-------LLGPYP---------REAAECFKKSCPVPCYYTKYE 305
[Close]
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. Planmine SMEST
Match: SMESG000074775.1 (SMESG000074775.1)

HSP 1 Score: 1028.08 bits (2657), Expect = 0.000e+0
Identity = 492/496 (99.19%), Postives = 494/496 (99.60%), Query Frame = 2 
Query:   80 MKELRYQPIVIFWLIVFTIVLTGFIIHTYYLYQRYIEEPIANILDITSNRVNWPAVTICPTNRIDGDRLQQNNSSLWESDFFKLKTFWQEFDRNLSVNIREEISENLSAEYMYLNSNESKAARFPFRQPQDFILKCSFGHVDCDFYIWKLHRHPSKFNCYSFTPPENLLGTAGKMNGMTLLLHYGKENLSFLRKLEKTFQFRGFYVAFHDSNSIPNFENHPLQVDVGKRTFIEIFTKKYQFIKRKQFNCVSNEESIHMINKINNYSTGKCYNDLVQANFLEKCNCLSIYHYPINERLGNFTEVLRSGCLSLGLPVQTLKDLISQYQSNSTLLNLLRKRVQCFRYFISSPAYINQHKHCLPLCNQTEFMNSYFNSDWPHDPYEAKLYIMKSLKRNLQLSLKYEYDEQMLRKWITFYEDLFSKPSNFSDYSETETTVKSRFALVHLYFRDSHVELMKQELVYPQITLWSEIGGAMGMWIGCSFFSIVYVAKVVYKHFF 1567
            MKELRYQPIVIFWLIVFTIVLTGFIIHTYYLYQRYIEEPIANILDITSNRVNWPAVTICPTNRIDGDRLQQ+NSSLWESDFFKLKTFWQEFDRNLSVNIREEISENLSAEYMYLNSNESKAARFPFRQPQDFILKCSFGHVDCDFYIWKLHRHPSKFNCYSFTPPENLLGTAGKMNGMTLLLHYGKENLSFLRKLEKTFQFRGFYVAFHDSNSIPNFENHPLQVDVGKRTFIEIFTKKYQFIKRKQFNCVSNEESIHMINKINNYS GKCYNDLVQANFLEKCNCLSIYHYPINERLGNFTEVLRSGCLSLGLPVQTLKDLISQYQSNSTLLNLLRKRVQCFRYFISSPAYINQHKHCLPLCNQTEFMNSYFNSDWPHDPYEAKLYIMKSLKRNLQLSLKYEYDEQMLRKWITFYEDLFSKPSNFSDYSETETT+KSRFALVHLYFRDSHVE MKQELVYPQITLWSEIGGAMGMWIGCSFFSIVYVAKVVYKHFF
Sbjct:    1 MKELRYQPIVIFWLIVFTIVLTGFIIHTYYLYQRYIEEPIANILDITSNRVNWPAVTICPTNRIDGDRLQQSNSSLWESDFFKLKTFWQEFDRNLSVNIREEISENLSAEYMYLNSNESKAARFPFRQPQDFILKCSFGHVDCDFYIWKLHRHPSKFNCYSFTPPENLLGTAGKMNGMTLLLHYGKENLSFLRKLEKTFQFRGFYVAFHDSNSIPNFENHPLQVDVGKRTFIEIFTKKYQFIKRKQFNCVSNEESIHMINKINNYSMGKCYNDLVQANFLEKCNCLSIYHYPINERLGNFTEVLRSGCLSLGLPVQTLKDLISQYQSNSTLLNLLRKRVQCFRYFISSPAYINQHKHCLPLCNQTEFMNSYFNSDWPHDPYEAKLYIMKSLKRNLQLSLKYEYDEQMLRKWITFYEDLFSKPSNFSDYSETETTIKSRFALVHLYFRDSHVEFMKQELVYPQITLWSEIGGAMGMWIGCSFFSIVYVAKVVYKHFF 496
[Close]
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. Planmine SMEST
Match: SMESG000074769.1 (SMESG000074769.1)

HSP 1 Score: 1023.08 bits (2644), Expect = 0.000e+0
Identity = 490/496 (98.79%), Postives = 492/496 (99.19%), Query Frame = 2 
Query:   80 MKELRYQPIVIFWLIVFTIVLTGFIIHTYYLYQRYIEEPIANILDITSNRVNWPAVTICPTNRIDGDRLQQNNSSLWESDFFKLKTFWQEFDRNLSVNIREEISENLSAEYMYLNSNESKAARFPFRQPQDFILKCSFGHVDCDFYIWKLHRHPSKFNCYSFTPPENLLGTAGKMNGMTLLLHYGKENLSFLRKLEKTFQFRGFYVAFHDSNSIPNFENHPLQVDVGKRTFIEIFTKKYQFIKRKQFNCVSNEESIHMINKINNYSTGKCYNDLVQANFLEKCNCLSIYHYPINERLGNFTEVLRSGCLSLGLPVQTLKDLISQYQSNSTLLNLLRKRVQCFRYFISSPAYINQHKHCLPLCNQTEFMNSYFNSDWPHDPYEAKLYIMKSLKRNLQLSLKYEYDEQMLRKWITFYEDLFSKPSNFSDYSETETTVKSRFALVHLYFRDSHVELMKQELVYPQITLWSEIGGAMGMWIGCSFFSIVYVAKVVYKHFF 1567
            MKELRYQPIVIFWLIVFTIVLTGFIIHTYYLYQRYIEEPIANILDITSNRVNWPAVTICPTNRIDGDRLQQ+NSSLWESDFFKLKTFWQEFDRNLSVNIREEISENLSAEYMYLNSNESKAARFPFRQPQDFILKCSFGHVDCDFYIWKLHRHPSKFNCYSFTPPENLLGTAGKMNGMTLLLHYGKENLSFLRKLEKTFQFRGFYVA HDSN IPNFENHPLQVDVGKRTFIEIFTKKYQFIKRKQFNCVSNEESIHMINKINNYS GKCYNDLVQANFLEKCNCLSIYHYPINERLGNFTEVLRSGCLSLGLPVQTLKDLISQYQSNSTLLNLLRKRVQCFRYFISSPAYINQHKHCLPLCNQTEFMNSYFNSDWPHDPYEAKLYIMKSLKRNLQLSLKYEYDEQMLRKWITFYEDLFSKPSNFSDYSETETT+KSRFALVHLYFRDSHVE MKQELVYPQITLWSEIGGAMGMWIGCSFFSIVYVAKVVYKHFF
Sbjct:    1 MKELRYQPIVIFWLIVFTIVLTGFIIHTYYLYQRYIEEPIANILDITSNRVNWPAVTICPTNRIDGDRLQQSNSSLWESDFFKLKTFWQEFDRNLSVNIREEISENLSAEYMYLNSNESKAARFPFRQPQDFILKCSFGHVDCDFYIWKLHRHPSKFNCYSFTPPENLLGTAGKMNGMTLLLHYGKENLSFLRKLEKTFQFRGFYVALHDSNLIPNFENHPLQVDVGKRTFIEIFTKKYQFIKRKQFNCVSNEESIHMINKINNYSMGKCYNDLVQANFLEKCNCLSIYHYPINERLGNFTEVLRSGCLSLGLPVQTLKDLISQYQSNSTLLNLLRKRVQCFRYFISSPAYINQHKHCLPLCNQTEFMNSYFNSDWPHDPYEAKLYIMKSLKRNLQLSLKYEYDEQMLRKWITFYEDLFSKPSNFSDYSETETTIKSRFALVHLYFRDSHVEFMKQELVYPQITLWSEIGGAMGMWIGCSFFSIVYVAKVVYKHFF 496
[Close]
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. Planmine SMEST
Match: SMESG000029017.1 (SMESG000029017.1)

HSP 1 Score: 69.707 bits (169), Expect = 2.412e-12
Identity = 66/353 (18.70%), Postives = 149/353 (42.21%), Query Frame = 2 
Query:  524 KLHRHPSKFNCYSFTPPENLLGTAGKMNGMTLLLHYGKENLSFLRKLEKTF------QFRGFYVAFHDSNSIPNFENHPLQVDVGKRTFIEIFTKKYQFIKRKQFNCVSNEESIHMINKINNYSTGKCYNDLVQANFLEKCNCLSIY---HYPINERLGNFTEVLRSGCLSLGLPVQTLKDLISQYQSNSTLLNLLRKRVQCFRYFISSPAYINQHKHCLPLCNQTEFMNSYFNSDWPHDPYEAKLYIMKSLKRNLQLSLKYEYDEQMLRKWITFYEDLFSKPSNFSDYSETETTVKSRFALVHLYFRDSHVELMKQELVYPQITLWSEIGGAMGMWIGCSFFSIVYVAKVVY 1555
            ++  H + FNC++  P + + GT   ++ + ++        S + +L+  F      +  G  +  H++ + P+ +     +  GK   I     K++F+      C  +++ I  ++++ NY+  +C +  +Q   LE+CNCLS     H   NE+      V R          +T+ ++       S  +N ++ R               Q   C P CN   +  +   + W   P   KL  +  +++ +++ ++   D+     + +F E+   K  N+ +  + ++  + RF  + L  ++ +  +  ++L+     L S IGG   ++IG +    + + + +Y
Sbjct:   36 RMFSHRNYFNCWTVEPKKTMSGTFHDISSLIVVASLIPS--SLIPELKDAFVMDILERGEGLKIVLHETGTYPDIDKDGFNIQPGKLNEIAYEPIKWKFLSTPVKICRDDQKEIIDLDRVFNYTFTQCVDAALQKLLLEECNCLSSLWPRHKTPNEKFPYCFNVWR----------ETVNEINETIICTSNFMNNMKARKLSV-----------QMNKCFPRCNFFTYSTTLSITKWL--PSIQKLDRIHRVQQEVEMLVRNRTDKTFKDNFSSFLEN---KYQNYRNSLDNDSLNEDRFTYIKLIRKNKNTTIKIEKLILDVAILLSRIGGLCSLFIGLTVAFFIELIEFIY 360
[Close]
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. Planmine SMEST
Match: SMESG000028687.1 (SMESG000028687.1)

HSP 1 Score: 63.929 bits (154), Expect = 2.016e-10
Identity = 118/534 (22.10%), Postives = 213/534 (39.89%), Query Frame = 2 
Query:   44 LKTIQNSRIFSLMKELR--YQPIVIFWLIVFTIVLTGFIIHTYYLYQRYIEEPIANILDITSN-RVNWPAVTICPTNRIDGDRLQQNNSSLWESDFFKLKTFW--QEFDRNLS-VNIREEISENLSAEYM----------YLNSNESKAARFPFRQPQDFILKCSFGHV--------DCD-FYIWKLHRHPSKFNCYSFTPPENLLGTAGKMNGMTLLLHYGKENLSFLRKLEKTF--QFRGFYVAFHDSNSIPNFENHPLQVDVGKRTFIEIFTKKYQFIKRKQFNCVSNEES--IHMINKINNYSTGKCYNDLVQANFLEKCNCLSIYHYPINERLGNFTEVLRSGCLSLGLPVQTLKDLISQYQSNSTLLNLLRKRVQCFRY---FISSPAYINQHKHCLPLCNQTEFMNSYFNSDWPHDPYEAKLYIMKSLKRNLQLSLKYEYDEQMLRKWITFYEDLFSKPSNFSDYSET---ETTVKSRFALVHLYFRDSHVELMKQELVYPQITLWSEIGGAMGMWIGCSFFSIVYV 1540
            L+  +N+ I  + K ++  ++P+   W+  F ++L+GF +   +L ++Y    + +   I +N +  +P+ T+C     +   L +N  ++     FKLK     +EF +N++   I+   ++N    Y           YL S  +K+      + QD I+ C   ++        DCD    W+   H    NCY F   E+L      +  M L L       + +         Q  G  +  H SN+ PNF    + +  G  T I++ T   +  K   +   SN+    I +  ++  YS   C    +Q +    CNC +I  YP N     F   L S    +      L D   + +  +T+  +  K   C  Y    + S         C   C+   +      S WP   ++ +    K+ K  L        D+Q L  +   Y     +  N+S+  +    E T++ +   V +   + +V L++++ V    +  S+ GG   +WIG + FSIV +
Sbjct:   47 LRFCENTTIRGVPKIIKSKHKPLRYMWMTCFILLLSGFSVCFIFLLKQYFAYDVIHPPRILTNSQAPFPSFTVC-----NLRPLARNIDTI-----FKLKNLKTPREFAKNVNNYAIKYFYNKNNLTLYGHASSIMLMGGYLESVPNKSYVELGHKKQDLIIHCRVTYMIGSKPHSKDCDELGKWRRIIHAQYVNCYMFDLIESLSNATNTLE-MFLYLDESINQATCIDCFSSDVKSQLSGALILIHRSNTFPNFNRDMINLQPGTLTEIKLKTIHNRH-KLPPYGRCSNKTPKWIKVFGELYAYSEDLCKLITIQGDLNHFCNCNAI-EYPFNYSSLKFCSALPSFSQRVSCN-NRLNDRKCETELKNTVKQISCKAKACLIYNNDIVPS---------CKLPCSFYSYETDRSTSTWPTKSWQLQWISTKAAKPLL--------DKQELDNY--RYAVKLQEKGNYSEALKILNKENTMEQKILAVMINRPNYNVHLVEEKEVLSLTSFLSQAGGLFSIWIGMTLFSIVEI 547
[Close]
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. Planmine SMEST
Match: SMESG000024270.1 (SMESG000024270.1)

HSP 1 Score: 63.5438 bits (153), Expect = 2.238e-10
Identity = 109/543 (20.07%), Postives = 209/543 (38.49%), Query Frame = 2 
Query:   20 CHKFSFMNLKTIQNSRIFSLMKELRYQPIVIFWLIVFTIVLTGFIIHTYYLYQRYIEEPIANILDITSNRVNWPAVTICPTNRIDGDRLQQNNSSLWESDFFKLKTFWQEFDRNLSVNIREEISENLSAEYMYLNSNESKAARFPFRQPQDFILKCSFGHVDCDFYIWKLHRHPSKFN-CYSFTPPENLLGTAGKMN---GMTLLLHYGKENLSFLRKLEKTFQFR---------GFYVAFHDSNSIPNFENHPLQVDVGKRTFIEIFTKKYQFIKRKQFNCVSNEESIHMINKINNYSTG------KCYNDLVQANFLEKCNCLSIYHYPINERLGNFTEVLRSGCLSLGLPVQTLKDLISQYQSNSTLLNLLRKRVQCFRYFISSPAYINQHKHCLPLCNQTEFMNSYFNSDWP----HDPYEAKLYIMKSLKRNLQLSLKYEYDEQMLRKWITFYEDLFSKPSNFSDYSE-----TETTVKSRFALVHLYFRDSHVELMKQELVYPQITLWSEIGGAMGMWIGCSFFSIVYVAKVVYKHF 1564
            CH+ +F  L  I  +R      ++R +   +FW+ +      GF+I+ YYL  +Y+E PI   +     R  +P ++IC TN I           L   ++     + +  D   S  +      NL AEY+++   +     F        I+ CS+   DC +  ++  RH   F  C++F   + ++    K+N   GM  +  + +  +     + + F            G  V  HD ++ P F  +   +D   +  + I +K++  +  +   C  ++E    ++   N ST        C    +Q N ++ C C+   H+P               CL     V  LKD + +  +  T   L +    C++                 LC+   F +    S +P       + + L I+  L+RN    +KY    ++  K +           N +   +      E  V   F ++ +      ++ +++ + YP   L S++GG +G+W+G S  +I     +++  F
Sbjct:   23 CHRSTFHGLSQIARAR------KIRQR---VFWITICGGASLGFLINIYYLLDKYLETPILTNVIQNYQRFIFPDISICFTNPIYYPPKDSEAHKLLMDNYQNYLYYKKNMDPFFSNRV------NL-AEYLFMTKTD-----FYGHHAWGSIVSCSYMGHDCSYKHFET-RHIYPFGVCHTFNSTKIMMKDIRKINSFSGMQSVKPFFQITVYKAVDMGENFNVDPFDDVTIPGGILVMIHDEHTFP-FIGNSYILDAYSQIDLRITSKQHLNVNNR---CKISQEFYTYMDLFENKSTAFSAKTEDCVYITIQINVMKNCQCI-WQHFPTI-----LVPPSTRYCLDGTFSVNHLKDCLRKTHAEITEEYLPK----CYQ----------------DLCDHKVFESVISQSKFPAVTERGTHASWLKILADLERN---EMKYFGQSELRTKALKMINASTRMTLNKAHKMQRIDLLDEEFVDRNFMMLRVVPNSFFMDKVEETMEYPISRLLSDVGGCVGLWVGASLITIFEFLDLIFDFF 510
The following BLAST results are available for this feature:
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 3
Match NameE-valueIdentityDescription
SCNN1B9.523e-819.62sodium channel epithelial 1 beta subunit [Source:H... [more]
SCNN1B1.228e-719.62sodium channel epithelial 1 beta subunit [Source:H... [more]
SCNN1B1.541e-719.62sodium channel epithelial 1 beta subunit [Source:H... [more]
back to top
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
asic-22.708e-1219.02Degenerin-like protein asic-2 [Source:UniProtKB/S... [more]
unc-1054.614e-1021.25Degenerin-like protein unc-105 [Source:UniProtKB/... [more]
unc-1054.614e-1021.25Degenerin-like protein unc-105 [Source:UniProtKB/... [more]
unc-1054.692e-1021.25Degenerin-like protein unc-105 [Source:UniProtKB/... [more]
unc-1054.692e-1021.25Degenerin-like protein unc-105 [Source:UniProtKB/... [more]
back to top
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0
Match NameE-valueIdentityDescription
back to top
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 2
Match NameE-valueIdentityDescription
asic4b1.014e-822.07acid-sensing (proton-gated) ion channel family mem... [more]
asic4a2.053e-719.71acid-sensing (proton-gated) ion channel family mem... [more]
back to top
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 1
Match NameE-valueIdentityDescription
foxe33.624e-820.43forkhead box E3 [Source:Xenbase;Acc:XB-GENE-480592... [more]
back to top
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 1
Match NameE-valueIdentityDescription
Scnn1g1.686e-619.68sodium channel, nonvoltage-gated 1 gamma [Source:M... [more]
back to top
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q22851|ASIC2_CAEEL3.445e-1119.02Degenerin-like protein asic-2 OS=Caenorhabditis el... [more]
sp|K7FQW8|SCNNB_PELSI2.219e-1021.51Amiloride-sensitive sodium channel subunit beta OS... [more]
sp|Q09274|UN105_CAEEL5.870e-921.25Degenerin-like protein unc-105 OS=Caenorhabditis e... [more]
sp|H1AFJ5|SCNNA_NEOFS1.867e-821.33Amiloride-sensitive sodium channel subunit alpha O... [more]
sp|Q25011|FANA_CORAP4.177e-820.54FMRFamide-activated amiloride-sensitive sodium cha... [more]
back to top
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A1I8IIE85.477e-2321.96RRM domain-containing protein OS=Macrostomum ligna... [more]
A0A267EP275.076e-2222.82Uncharacterized protein OS=Macrostomum lignano OX=... [more]
A0A267GSY31.548e-2123.03Uncharacterized protein OS=Macrostomum lignano OX=... [more]
A0A267G3Q52.796e-1922.02Uncharacterized protein OS=Macrostomum lignano OX=... [more]
A0A267GVL08.494e-1922.22Uncharacterized protein (Fragment) OS=Macrostomum ... [more]
back to top
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 1
Match NameE-valueIdentityDescription
asic4b8.158e-622.10acid-sensing ion channel 4 [Source:NCBI gene;Acc:1... [more]
back to top
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
back to top
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
back to top
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 2
Match NameE-valueIdentityDescription
EDO421372.231e-1321.57Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO308943.114e-720.28Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
back to top
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 0
Match NameE-valueIdentityDescription
back to top
BLAST of Amiloride-sensitive sodium channel subunit gamma vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000074775.10.000e+099.19SMESG000074775.1[more]
SMESG000074769.10.000e+098.79SMESG000074769.1[more]
SMESG000029017.12.412e-1218.70SMESG000029017.1[more]
SMESG000028687.12.016e-1022.10SMESG000028687.1[more]
SMESG000024270.12.238e-1020.07SMESG000024270.1[more]
back to top
Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30017185 ID=SMED30017185|Name=Amiloride-sensitive sodium channel subunit gamma|organism=Schmidtea mediterranea sexual|type=transcript|length=1675bp
TAAGACGTAAAAAATCTGTTGTCACAAATTTTCATTCATGAATTTGAAAA
CAATCCAAAATTCCAGAATTTTTTCATTAATGAAAGAATTAAGATATCAA
CCAATTGTTATTTTTTGGTTGATTGTTTTCACAATTGTATTAACGGGATT
TATCATTCATACGTATTATCTCTACCAACGGTACATCGAGGAGCCGATTG
CAAACATCTTAGATATCACCTCGAACAGAGTAAATTGGCCGGCGGTCACG
ATTTGTCCCACTAATCGCATCGACGGTGATCGACTCCAGCAAAACAACTC
CAGTTTATGGGAAAGTGATTTTTTTAAACTCAAAACATTTTGGCAAGAAT
TTGACCGAAACCTCTCTGTAAATATTCGAGAAGAAATCTCAGAAAACCTT
TCAGCAGAATACATGTACTTAAACTCCAACGAATCCAAAGCAGCGCGATT
TCCGTTCCGGCAACCGCAGGATTTCATCTTGAAATGTAGTTTCGGTCATG
TCGACTGTGATTTTTATATTTGGAAGTTACATAGACATCCTTCAAAATTC
AATTGTTATTCATTTACCCCTCCGGAAAACCTTCTTGGAACTGCTGGGAA
AATGAATGGTATGACTTTGTTACTCCACTATGGAAAAGAAAATCTATCTT
TTCTGAGGAAATTGGAGAAAACTTTCCAATTTCGAGGGTTTTATGTTGCT
TTTCATGATTCGAATTCGATTCCGAATTTCGAAAACCATCCTTTGCAAGT
CGATGTAGGAAAAAGAACCTTTATTGAAATATTTACAAAGAAATATCAAT
TTATCAAACGTAAACAATTCAATTGTGTATCTAACGAAGAATCGATTCAC
ATGATAAACAAAATAAACAACTATTCCACGGGTAAATGTTACAACGACTT
AGTTCAGGCGAACTTTTTAGAAAAATGCAATTGCTTGTCCATTTATCACT
ACCCTATAAATGAAAGGCTAGGTAACTTCACTGAGGTTTTAAGATCAGGA
TGCCTTTCGCTTGGACTACCGGTTCAAACTCTCAAAGACTTAATTAGCCA
ATATCAATCAAATTCTACCTTACTCAACCTTTTACGAAAAAGAGTTCAGT
GCTTTCGATATTTTATCAGCAGTCCCGCCTATATTAATCAACACAAACAT
TGCCTTCCGTTGTGCAATCAGACCGAATTTATGAATTCCTATTTCAACTC
GGACTGGCCTCATGATCCTTATGAAGCTAAGTTGTATATTATGAAAAGCT
TGAAGCGTAATCTTCAATTGAGTTTAAAATATGAGTATGATGAACAAATG
TTAAGGAAGTGGATCACTTTTTATGAGGATTTATTTAGCAAACCTAGCAA
CTTCAGCGATTACTCTGAAACGGAAACTACTGTTAAATCAAGATTTGCTT
TAGTTCATTTATATTTTCGAGATTCTCACGTAGAATTAATGAAACAGGAA
TTAGTTTATCCCCAAATAACCCTATGGTCAGAAATTGGCGGAGCAATGGG
CATGTGGATCGGATGCAGTTTCTTTTCCATCGTATATGTCGCCAAGGTTG
TTTATAAGCACTTTTTCTAAAGATATATTAAAGACATGAAACCATTTTAG
GCGTGAATTTTTCTTTAGGAAAACTATATTTTATCTCTAACTAAGCTGAT
AGATAAATATATAAAGCACTCCCGT
back to top

protein sequence of SMED30017185-orf-1

>SMED30017185-orf-1 ID=SMED30017185-orf-1|Name=SMED30017185-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=511bp
MNLKTIQNSRIFSLMKELRYQPIVIFWLIVFTIVLTGFIIHTYYLYQRYI
EEPIANILDITSNRVNWPAVTICPTNRIDGDRLQQNNSSLWESDFFKLKT
FWQEFDRNLSVNIREEISENLSAEYMYLNSNESKAARFPFRQPQDFILKC
SFGHVDCDFYIWKLHRHPSKFNCYSFTPPENLLGTAGKMNGMTLLLHYGK
ENLSFLRKLEKTFQFRGFYVAFHDSNSIPNFENHPLQVDVGKRTFIEIFT
KKYQFIKRKQFNCVSNEESIHMINKINNYSTGKCYNDLVQANFLEKCNCL
SIYHYPINERLGNFTEVLRSGCLSLGLPVQTLKDLISQYQSNSTLLNLLR
KRVQCFRYFISSPAYINQHKHCLPLCNQTEFMNSYFNSDWPHDPYEAKLY
IMKSLKRNLQLSLKYEYDEQMLRKWITFYEDLFSKPSNFSDYSETETTVK
SRFALVHLYFRDSHVELMKQELVYPQITLWSEIGGAMGMWIGCSFFSIVY
VAKVVYKHFF*
back to top
Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000420parapharyngeal region
Vocabulary: INTERPRO
TermDefinition
IPR001873ENaC
Vocabulary: cellular component
TermDefinition
GO:0016020membrane
GO:0016021integral component of membrane
Vocabulary: molecular function
TermDefinition
GO:0005272sodium channel activity
Vocabulary: biological process
TermDefinition
GO:0006814sodium ion transport
GO:0006810transport
GO:0006811ion transport
GO:0035725sodium ion transmembrane transport
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR001873Epithelial sodium channelPRINTSPR01078AMINACHANNELcoord: 63..79
score: 35.53
coord: 161..177
score: 32.24
coord: 187..205
score: 21.89
coord: 147..158
score: 43.67
coord: 279..290
score: 30.67
coord: 290..307
score: 22.22
coord: 217..235
score: 21.26
IPR001873Epithelial sodium channelPFAMPF00858ASCcoord: 25..499
e-value: 3.1E-59
score: 201.1
IPR001873Epithelial sodium channelPANTHERPTHR11690AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATEDcoord: 25..503
NoneNo IPR availableGENE3DG3DSA:1.10.3590.10coord: 76..217
e-value: 3.9E-49
score: 169.7
NoneNo IPR availableGENE3DG3DSA:1.10.287.820coord: 255..376
e-value: 3.9E-49
score: 169.7
NoneNo IPR availableGENE3DG3DSA:2.60.470.10coord: 54..472
e-value: 3.9E-49
score: 169.7
NoneNo IPR availableGENE3DG3DSA:1.10.287.770coord: 25..499
e-value: 3.9E-49
score: 169.7
NoneNo IPR availableTMHMMTMhelixcoord: 23..45
NoneNo IPR availableTMHMMTMhelixcoord: 477..499